data_5AG1 # _entry.id 5AG1 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5AG1 PDBE EBI-62853 WWPDB D_1290062853 # _pdbx_database_related.db_name PDB _pdbx_database_related.db_id 5AG0 _pdbx_database_related.content_type unspecified _pdbx_database_related.details 'DYP-TYPE PEROXIDASE OF AURICULARIA AURICULA-JUDAE ( AAUDYPI) CRYSTALLIZED AT PH 6.5' # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 5AG1 _pdbx_database_status.deposit_site PDBE _pdbx_database_status.process_site PDBE _pdbx_database_status.SG_entry . _pdbx_database_status.recvd_initial_deposition_date 2015-01-27 _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_sf ? _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Strittmatter, E.' 1 'Piontek, K.' 2 'Plattner, D.A.' 3 # _citation.id primary _citation.title 'Crystallographic Trapping of a Covalently Modified Heme in a Dye-Decolorizing Peroxidase' _citation.journal_abbrev 'To be Published' _citation.journal_volume ? _citation.page_first ? _citation.page_last ? _citation.year ? _citation.journal_id_ASTM ? _citation.country ? _citation.journal_id_ISSN ? _citation.journal_id_CSD 0353 _citation.book_publisher ? _citation.pdbx_database_id_PubMed ? _citation.pdbx_database_id_DOI ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Strittmatter, E.' 1 primary 'Piontek, K.' 2 primary 'Plattner, D.A.' 3 # _cell.entry_id 5AG1 _cell.length_a 66.000 _cell.length_b 46.780 _cell.length_c 148.150 _cell.angle_alpha 90.00 _cell.angle_beta 100.53 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? # _symmetry.entry_id 5AG1 _symmetry.space_group_name_H-M 'P 1 21 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 4 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer nat 'DYE-DECOLORIZING PEROXIDASE' 46805.855 2 1.11.1.19 ? 'DYP-TYPE PEROXIDASE DOMAIN, RESIDUES 64-509' ;INCLUDING THE TWO PROTEIN CHAINS, THE CO- FACTOR DELTA-MESO NITROHEME, CARBOHYDRATE MOLECULES, CACODYLATE, FORMATE, GLYCEROL, NITRITE, AND WATER MOLECULES. ; 2 non-polymer syn 'CACODYLATE ION' 136.989 2 ? ? ? ? 3 non-polymer syn GLYCEROL 92.094 8 ? ? ? ? 4 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 6 ? ? ? ? 5 non-polymer syn 'DELTA-MESO NITROHEME' 659.469 2 ? ? ? ? 6 non-polymer syn 'FORMIC ACID' 46.025 1 ? ? ? ? 7 non-polymer syn 'NITRITE ION' 46.005 2 ? ? ? ? 8 water nat water 18.015 893 ? ? ? ? # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;SLNTDDIQGDILVGMHKQKQLFYFFAINDPATFKTHLASDIAPVVASVTQLSNVATQPLVALNIAFSNTGLLALGVTDNL GDSLFANGQAKDATSFKESTSSWVPQFAGTGIHGVIILASDTTDLIDQQVASIESTFGSSISKLYSLSASIRPGNEAGHE MFGFLDGIAQPAINGFNTPLPGQNIVDAGVIITGATNDPITRPSWAVGGSFLAFRQLEQLVPEFNKYLLDNAPAGSGSLQ ARADLLGARMVGRWKSGAPIDLTPTADDPALGADAQRNNNFTYSHAGFDLGSDQSHCPFSAHIRKTRPRADLGGSLTPPN LSAGANSIMRSGIPYGPEVTSAESASNTTTQERGLAFVAYQAQLSQGFHFLQQTWADNANFPPGKTPATVGLDPIIGQNN GQPRVVNGLLPSNSSASLSIPQFVVSHGGEYFFSPPISAIGGRLSA ; _entity_poly.pdbx_seq_one_letter_code_can ;SLNTDDIQGDILVGMHKQKQLFYFFAINDPATFKTHLASDIAPVVASVTQLSNVATQPLVALNIAFSNTGLLALGVTDNL GDSLFANGQAKDATSFKESTSSWVPQFAGTGIHGVIILASDTTDLIDQQVASIESTFGSSISKLYSLSASIRPGNEAGHE MFGFLDGIAQPAINGFNTPLPGQNIVDAGVIITGATNDPITRPSWAVGGSFLAFRQLEQLVPEFNKYLLDNAPAGSGSLQ ARADLLGARMVGRWKSGAPIDLTPTADDPALGADAQRNNNFTYSHAGFDLGSDQSHCPFSAHIRKTRPRADLGGSLTPPN LSAGANSIMRSGIPYGPEVTSAESASNTTTQERGLAFVAYQAQLSQGFHFLQQTWADNANFPPGKTPATVGLDPIIGQNN GQPRVVNGLLPSNSSASLSIPQFVVSHGGEYFFSPPISAIGGRLSA ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 SER n 1 2 LEU n 1 3 ASN n 1 4 THR n 1 5 ASP n 1 6 ASP n 1 7 ILE n 1 8 GLN n 1 9 GLY n 1 10 ASP n 1 11 ILE n 1 12 LEU n 1 13 VAL n 1 14 GLY n 1 15 MET n 1 16 HIS n 1 17 LYS n 1 18 GLN n 1 19 LYS n 1 20 GLN n 1 21 LEU n 1 22 PHE n 1 23 TYR n 1 24 PHE n 1 25 PHE n 1 26 ALA n 1 27 ILE n 1 28 ASN n 1 29 ASP n 1 30 PRO n 1 31 ALA n 1 32 THR n 1 33 PHE n 1 34 LYS n 1 35 THR n 1 36 HIS n 1 37 LEU n 1 38 ALA n 1 39 SER n 1 40 ASP n 1 41 ILE n 1 42 ALA n 1 43 PRO n 1 44 VAL n 1 45 VAL n 1 46 ALA n 1 47 SER n 1 48 VAL n 1 49 THR n 1 50 GLN n 1 51 LEU n 1 52 SER n 1 53 ASN n 1 54 VAL n 1 55 ALA n 1 56 THR n 1 57 GLN n 1 58 PRO n 1 59 LEU n 1 60 VAL n 1 61 ALA n 1 62 LEU n 1 63 ASN n 1 64 ILE n 1 65 ALA n 1 66 PHE n 1 67 SER n 1 68 ASN n 1 69 THR n 1 70 GLY n 1 71 LEU n 1 72 LEU n 1 73 ALA n 1 74 LEU n 1 75 GLY n 1 76 VAL n 1 77 THR n 1 78 ASP n 1 79 ASN n 1 80 LEU n 1 81 GLY n 1 82 ASP n 1 83 SER n 1 84 LEU n 1 85 PHE n 1 86 ALA n 1 87 ASN n 1 88 GLY n 1 89 GLN n 1 90 ALA n 1 91 LYS n 1 92 ASP n 1 93 ALA n 1 94 THR n 1 95 SER n 1 96 PHE n 1 97 LYS n 1 98 GLU n 1 99 SER n 1 100 THR n 1 101 SER n 1 102 SER n 1 103 TRP n 1 104 VAL n 1 105 PRO n 1 106 GLN n 1 107 PHE n 1 108 ALA n 1 109 GLY n 1 110 THR n 1 111 GLY n 1 112 ILE n 1 113 HIS n 1 114 GLY n 1 115 VAL n 1 116 ILE n 1 117 ILE n 1 118 LEU n 1 119 ALA n 1 120 SER n 1 121 ASP n 1 122 THR n 1 123 THR n 1 124 ASP n 1 125 LEU n 1 126 ILE n 1 127 ASP n 1 128 GLN n 1 129 GLN n 1 130 VAL n 1 131 ALA n 1 132 SER n 1 133 ILE n 1 134 GLU n 1 135 SER n 1 136 THR n 1 137 PHE n 1 138 GLY n 1 139 SER n 1 140 SER n 1 141 ILE n 1 142 SER n 1 143 LYS n 1 144 LEU n 1 145 TYR n 1 146 SER n 1 147 LEU n 1 148 SER n 1 149 ALA n 1 150 SER n 1 151 ILE n 1 152 ARG n 1 153 PRO n 1 154 GLY n 1 155 ASN n 1 156 GLU n 1 157 ALA n 1 158 GLY n 1 159 HIS n 1 160 GLU n 1 161 MET n 1 162 PHE n 1 163 GLY n 1 164 PHE n 1 165 LEU n 1 166 ASP n 1 167 GLY n 1 168 ILE n 1 169 ALA n 1 170 GLN n 1 171 PRO n 1 172 ALA n 1 173 ILE n 1 174 ASN n 1 175 GLY n 1 176 PHE n 1 177 ASN n 1 178 THR n 1 179 PRO n 1 180 LEU n 1 181 PRO n 1 182 GLY n 1 183 GLN n 1 184 ASN n 1 185 ILE n 1 186 VAL n 1 187 ASP n 1 188 ALA n 1 189 GLY n 1 190 VAL n 1 191 ILE n 1 192 ILE n 1 193 THR n 1 194 GLY n 1 195 ALA n 1 196 THR n 1 197 ASN n 1 198 ASP n 1 199 PRO n 1 200 ILE n 1 201 THR n 1 202 ARG n 1 203 PRO n 1 204 SER n 1 205 TRP n 1 206 ALA n 1 207 VAL n 1 208 GLY n 1 209 GLY n 1 210 SER n 1 211 PHE n 1 212 LEU n 1 213 ALA n 1 214 PHE n 1 215 ARG n 1 216 GLN n 1 217 LEU n 1 218 GLU n 1 219 GLN n 1 220 LEU n 1 221 VAL n 1 222 PRO n 1 223 GLU n 1 224 PHE n 1 225 ASN n 1 226 LYS n 1 227 TYR n 1 228 LEU n 1 229 LEU n 1 230 ASP n 1 231 ASN n 1 232 ALA n 1 233 PRO n 1 234 ALA n 1 235 GLY n 1 236 SER n 1 237 GLY n 1 238 SER n 1 239 LEU n 1 240 GLN n 1 241 ALA n 1 242 ARG n 1 243 ALA n 1 244 ASP n 1 245 LEU n 1 246 LEU n 1 247 GLY n 1 248 ALA n 1 249 ARG n 1 250 MET n 1 251 VAL n 1 252 GLY n 1 253 ARG n 1 254 TRP n 1 255 LYS n 1 256 SER n 1 257 GLY n 1 258 ALA n 1 259 PRO n 1 260 ILE n 1 261 ASP n 1 262 LEU n 1 263 THR n 1 264 PRO n 1 265 THR n 1 266 ALA n 1 267 ASP n 1 268 ASP n 1 269 PRO n 1 270 ALA n 1 271 LEU n 1 272 GLY n 1 273 ALA n 1 274 ASP n 1 275 ALA n 1 276 GLN n 1 277 ARG n 1 278 ASN n 1 279 ASN n 1 280 ASN n 1 281 PHE n 1 282 THR n 1 283 TYR n 1 284 SER n 1 285 HIS n 1 286 ALA n 1 287 GLY n 1 288 PHE n 1 289 ASP n 1 290 LEU n 1 291 GLY n 1 292 SER n 1 293 ASP n 1 294 GLN n 1 295 SER n 1 296 HIS n 1 297 CYS n 1 298 PRO n 1 299 PHE n 1 300 SER n 1 301 ALA n 1 302 HIS n 1 303 ILE n 1 304 ARG n 1 305 LYS n 1 306 THR n 1 307 ARG n 1 308 PRO n 1 309 ARG n 1 310 ALA n 1 311 ASP n 1 312 LEU n 1 313 GLY n 1 314 GLY n 1 315 SER n 1 316 LEU n 1 317 THR n 1 318 PRO n 1 319 PRO n 1 320 ASN n 1 321 LEU n 1 322 SER n 1 323 ALA n 1 324 GLY n 1 325 ALA n 1 326 ASN n 1 327 SER n 1 328 ILE n 1 329 MET n 1 330 ARG n 1 331 SER n 1 332 GLY n 1 333 ILE n 1 334 PRO n 1 335 TYR n 1 336 GLY n 1 337 PRO n 1 338 GLU n 1 339 VAL n 1 340 THR n 1 341 SER n 1 342 ALA n 1 343 GLU n 1 344 SER n 1 345 ALA n 1 346 SER n 1 347 ASN n 1 348 THR n 1 349 THR n 1 350 THR n 1 351 GLN n 1 352 GLU n 1 353 ARG n 1 354 GLY n 1 355 LEU n 1 356 ALA n 1 357 PHE n 1 358 VAL n 1 359 ALA n 1 360 TYR n 1 361 GLN n 1 362 ALA n 1 363 GLN n 1 364 LEU n 1 365 SER n 1 366 GLN n 1 367 GLY n 1 368 PHE n 1 369 HIS n 1 370 PHE n 1 371 LEU n 1 372 GLN n 1 373 GLN n 1 374 THR n 1 375 TRP n 1 376 ALA n 1 377 ASP n 1 378 ASN n 1 379 ALA n 1 380 ASN n 1 381 PHE n 1 382 PRO n 1 383 PRO n 1 384 GLY n 1 385 LYS n 1 386 THR n 1 387 PRO n 1 388 ALA n 1 389 THR n 1 390 VAL n 1 391 GLY n 1 392 LEU n 1 393 ASP n 1 394 PRO n 1 395 ILE n 1 396 ILE n 1 397 GLY n 1 398 GLN n 1 399 ASN n 1 400 ASN n 1 401 GLY n 1 402 GLN n 1 403 PRO n 1 404 ARG n 1 405 VAL n 1 406 VAL n 1 407 ASN n 1 408 GLY n 1 409 LEU n 1 410 LEU n 1 411 PRO n 1 412 SER n 1 413 ASN n 1 414 SER n 1 415 SER n 1 416 ALA n 1 417 SER n 1 418 LEU n 1 419 SER n 1 420 ILE n 1 421 PRO n 1 422 GLN n 1 423 PHE n 1 424 VAL n 1 425 VAL n 1 426 SER n 1 427 HIS n 1 428 GLY n 1 429 GLY n 1 430 GLU n 1 431 TYR n 1 432 PHE n 1 433 PHE n 1 434 SER n 1 435 PRO n 1 436 PRO n 1 437 ILE n 1 438 SER n 1 439 ALA n 1 440 ILE n 1 441 GLY n 1 442 GLY n 1 443 ARG n 1 444 LEU n 1 445 SER n 1 446 ALA n # _entity_src_nat.entity_id 1 _entity_src_nat.pdbx_src_id 1 _entity_src_nat.pdbx_alt_source_flag sample _entity_src_nat.pdbx_beg_seq_num ? _entity_src_nat.pdbx_end_seq_num ? _entity_src_nat.common_name 'EAR FUNGUS' _entity_src_nat.pdbx_organism_scientific 'AURICULARIA AURICULA-JUDAE' _entity_src_nat.pdbx_ncbi_taxonomy_id 29892 _entity_src_nat.genus ? _entity_src_nat.species ? _entity_src_nat.strain SXM9-C021 _entity_src_nat.tissue ? _entity_src_nat.tissue_fraction ? _entity_src_nat.pdbx_secretion ? _entity_src_nat.pdbx_fragment ? _entity_src_nat.pdbx_variant ? _entity_src_nat.pdbx_cell_line ? _entity_src_nat.pdbx_atcc ? _entity_src_nat.pdbx_cellular_location ? _entity_src_nat.pdbx_organ ? _entity_src_nat.pdbx_organelle ? _entity_src_nat.pdbx_cell ? _entity_src_nat.pdbx_plasmid_name ? _entity_src_nat.pdbx_plasmid_details ? _entity_src_nat.details 'GERMAN COLLECTION OF MICROORGANISMS (DSM), ACCESS NUMBER DSM 11326' # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code I2DBY1_9HOMO _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ? _struct_ref.pdbx_align_begin ? _struct_ref.pdbx_db_accession I2DBY1 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5AG1 A 1 ? 446 ? I2DBY1 64 ? 509 ? 3 448 2 1 5AG1 B 1 ? 446 ? I2DBY1 64 ? 509 ? 3 448 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CAC non-polymer . 'CACODYLATE ION' dimethylarsinate 'C2 H6 As O2 -1' 136.989 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FMT non-polymer . 'FORMIC ACID' ? 'C H2 O2' 46.025 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 N7H non-polymer . 'DELTA-MESO NITROHEME' ? 'C34 H29 Fe N5 O6' 659.469 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 NO2 non-polymer . 'NITRITE ION' ? 'N O2 -1' 46.005 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 5AG1 _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.2 _exptl_crystal.density_percent_sol 44 _exptl_crystal.description NONE # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method ? _exptl_crystal_grow.temp ? _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details '0.17 M SODIUM ACETATE TRIHYDRATE, 0.085 M SODIUM CACODYLATE PH 6.5, 25% (W/V) PEG 8000, 15% (V/V) GLYCEROL' # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 315r' _diffrn_detector.pdbx_collection_date 2013-06-28 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.939 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'ESRF BEAMLINE ID14-4' _diffrn_source.pdbx_synchrotron_site ESRF _diffrn_source.pdbx_synchrotron_beamline ID14-4 _diffrn_source.pdbx_wavelength 0.939 _diffrn_source.pdbx_wavelength_list ? # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 5AG1 _reflns.observed_criterion_sigma_I -3.0 _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 44.57 _reflns.d_resolution_high 1.85 _reflns.number_obs 75411 _reflns.number_all ? _reflns.percent_possible_obs 98.2 _reflns.pdbx_Rmerge_I_obs 0.10 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 10.11 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 3.2 # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 1.85 _reflns_shell.d_res_low 1.96 _reflns_shell.percent_possible_all 91.4 _reflns_shell.Rmerge_I_obs 0.51 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 2.10 _reflns_shell.pdbx_redundancy 2.8 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 5AG1 _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 71625 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 44.57 _refine.ls_d_res_high 1.85 _refine.ls_percent_reflns_obs 98.41 _refine.ls_R_factor_obs 0.17655 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.17451 _refine.ls_R_factor_R_free 0.21547 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.0 _refine.ls_number_reflns_R_free 3770 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.954 _refine.correlation_coeff_Fo_to_Fc_free 0.930 _refine.B_iso_mean 16.212 _refine.aniso_B[1][1] -0.33 _refine.aniso_B[2][2] 0.17 _refine.aniso_B[3][3] 0.38 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] -0.65 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ;HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. U VALUES REFINED INDIVIDUALLY PROTEIN WAS TREATED WITH PROLI NONOATE AND PERACETIC ACID PRIOR TO CRYSTALLIZATION. ; _refine.pdbx_starting_model 'PDB ENTRY 4AU9' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.145 _refine.pdbx_overall_ESU_R_Free 0.135 _refine.overall_SU_ML 0.093 _refine.pdbx_overall_phase_error ? _refine.overall_SU_B 3.131 _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6604 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 243 _refine_hist.number_atoms_solvent 893 _refine_hist.number_atoms_total 7740 _refine_hist.d_res_high 1.85 _refine_hist.d_res_low 44.57 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.003 0.019 ? 7097 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 0.674 1.985 ? 9708 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 6.781 5.000 ? 910 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 37.936 25.000 ? 292 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 11.719 15.000 ? 994 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 22.795 15.000 ? 28 'X-RAY DIFFRACTION' ? r_chiral_restr 0.051 0.200 ? 1086 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.008 0.021 ? 5521 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 0.862 1.918 ? 3616 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it 1.343 3.231 ? 4534 'X-RAY DIFFRACTION' ? r_mcangle_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_scbond_it 1.212 2.048 ? 3481 'X-RAY DIFFRACTION' ? r_scbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_scangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_scangle_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_long_range_B_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_long_range_B_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 1.850 _refine_ls_shell.d_res_low 1.898 _refine_ls_shell.number_reflns_R_work 4603 _refine_ls_shell.R_factor_R_work 0.291 _refine_ls_shell.percent_reflns_obs 86.49 _refine_ls_shell.R_factor_R_free 0.315 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 242 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? # _struct.entry_id 5AG1 _struct.title 'DyP-type peroxidase of Auricularia auricula-judae (AauDyPI) with meso- nitrated heme' _struct.pdbx_descriptor 'DYE-DECOLORIZING PEROXIDASE (E.C.1.11.1.19)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 5AG1 _struct_keywords.pdbx_keywords OXIDOREDUCTASE _struct_keywords.text 'OXIDOREDUCTASE, DYP, FUNGAL, HEME, GLYCOPROTEIN, NITRATION' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 3 ? E N N 3 ? F N N 3 ? G N N 3 ? H N N 4 ? I N N 4 ? J N N 4 ? K N N 4 ? L N N 5 ? M N N 6 ? N N N 7 ? O N N 2 ? P N N 3 ? Q N N 3 ? R N N 3 ? S N N 3 ? T N N 4 ? U N N 4 ? V N N 5 ? W N N 7 ? X N N 8 ? Y N N 8 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 GLN A 8 ? VAL A 13 ? GLN A 10 VAL A 15 1 ? 6 HELX_P HELX_P2 2 ASP A 29 ? ASP A 40 ? ASP A 31 ASP A 42 1 ? 12 HELX_P HELX_P3 3 ILE A 41 ? VAL A 44 ? ILE A 43 VAL A 46 5 ? 4 HELX_P HELX_P4 4 SER A 47 ? SER A 52 ? SER A 49 SER A 54 1 ? 6 HELX_P HELX_P5 5 ASN A 53 ? GLN A 57 ? ASN A 55 GLN A 59 5 ? 5 HELX_P HELX_P6 6 SER A 67 ? LEU A 74 ? SER A 69 LEU A 76 1 ? 8 HELX_P HELX_P7 7 ASP A 82 ? GLY A 88 ? ASP A 84 GLY A 90 1 ? 7 HELX_P HELX_P8 8 GLY A 88 ? ALA A 93 ? GLY A 90 ALA A 95 1 ? 6 HELX_P HELX_P9 9 THR A 94 ? LYS A 97 ? THR A 96 LYS A 99 5 ? 4 HELX_P HELX_P10 10 SER A 99 ? TRP A 103 ? SER A 101 TRP A 105 5 ? 5 HELX_P HELX_P11 11 VAL A 104 ? ALA A 108 ? VAL A 106 ALA A 110 5 ? 5 HELX_P HELX_P12 12 THR A 122 ? GLY A 138 ? THR A 124 GLY A 140 1 ? 17 HELX_P HELX_P13 13 PRO A 153 ? ALA A 157 ? PRO A 155 ALA A 159 5 ? 5 HELX_P HELX_P14 14 ASP A 187 ? ILE A 191 ? ASP A 189 ILE A 193 5 ? 5 HELX_P HELX_P15 15 PRO A 203 ? VAL A 207 ? PRO A 205 VAL A 209 5 ? 5 HELX_P HELX_P16 16 LEU A 220 ? ALA A 232 ? LEU A 222 ALA A 234 1 ? 13 HELX_P HELX_P17 17 SER A 238 ? GLY A 252 ? SER A 240 GLY A 254 1 ? 15 HELX_P HELX_P18 18 ASP A 268 ? ALA A 273 ? ASP A 270 ALA A 275 1 ? 6 HELX_P HELX_P19 19 ALA A 301 ? ARG A 307 ? ALA A 303 ARG A 309 1 ? 7 HELX_P HELX_P20 20 PRO A 308 ? GLY A 313 ? PRO A 310 GLY A 315 5 ? 6 HELX_P HELX_P21 21 ALA A 323 ? SER A 327 ? ALA A 325 SER A 329 5 ? 5 HELX_P HELX_P22 22 THR A 340 ? ASN A 347 ? THR A 342 ASN A 349 1 ? 8 HELX_P HELX_P23 23 GLY A 367 ? THR A 374 ? GLY A 369 THR A 376 1 ? 8 HELX_P HELX_P24 24 PRO A 436 ? GLY A 441 ? PRO A 438 GLY A 443 1 ? 6 HELX_P HELX_P25 25 GLY A 442 ? ALA A 446 ? GLY A 444 ALA A 448 5 ? 5 HELX_P HELX_P26 26 GLN B 8 ? VAL B 13 ? GLN B 10 VAL B 15 1 ? 6 HELX_P HELX_P27 27 ASP B 29 ? ASP B 40 ? ASP B 31 ASP B 42 1 ? 12 HELX_P HELX_P28 28 ILE B 41 ? VAL B 44 ? ILE B 43 VAL B 46 5 ? 4 HELX_P HELX_P29 29 SER B 47 ? ASN B 53 ? SER B 49 ASN B 55 1 ? 7 HELX_P HELX_P30 30 VAL B 54 ? GLN B 57 ? VAL B 56 GLN B 59 5 ? 4 HELX_P HELX_P31 31 SER B 67 ? LEU B 74 ? SER B 69 LEU B 76 1 ? 8 HELX_P HELX_P32 32 ASP B 82 ? GLY B 88 ? ASP B 84 GLY B 90 1 ? 7 HELX_P HELX_P33 33 GLY B 88 ? ALA B 93 ? GLY B 90 ALA B 95 1 ? 6 HELX_P HELX_P34 34 THR B 94 ? LYS B 97 ? THR B 96 LYS B 99 5 ? 4 HELX_P HELX_P35 35 SER B 99 ? TRP B 103 ? SER B 101 TRP B 105 5 ? 5 HELX_P HELX_P36 36 VAL B 104 ? ALA B 108 ? VAL B 106 ALA B 110 5 ? 5 HELX_P HELX_P37 37 THR B 122 ? GLY B 138 ? THR B 124 GLY B 140 1 ? 17 HELX_P HELX_P38 38 PRO B 153 ? ALA B 157 ? PRO B 155 ALA B 159 5 ? 5 HELX_P HELX_P39 39 ASP B 187 ? ILE B 191 ? ASP B 189 ILE B 193 5 ? 5 HELX_P HELX_P40 40 PRO B 203 ? VAL B 207 ? PRO B 205 VAL B 209 5 ? 5 HELX_P HELX_P41 41 LEU B 220 ? ALA B 232 ? LEU B 222 ALA B 234 1 ? 13 HELX_P HELX_P42 42 SER B 238 ? GLY B 252 ? SER B 240 GLY B 254 1 ? 15 HELX_P HELX_P43 43 ASP B 268 ? ASP B 274 ? ASP B 270 ASP B 276 1 ? 7 HELX_P HELX_P44 44 ALA B 301 ? ARG B 307 ? ALA B 303 ARG B 309 1 ? 7 HELX_P HELX_P45 45 PRO B 308 ? GLY B 313 ? PRO B 310 GLY B 315 5 ? 6 HELX_P HELX_P46 46 ALA B 323 ? SER B 327 ? ALA B 325 SER B 329 5 ? 5 HELX_P HELX_P47 47 THR B 340 ? ASN B 347 ? THR B 342 ASN B 349 1 ? 8 HELX_P HELX_P48 48 GLY B 367 ? THR B 374 ? GLY B 369 THR B 376 1 ? 8 HELX_P HELX_P49 49 PRO B 436 ? GLY B 441 ? PRO B 438 GLY B 443 1 ? 6 HELX_P HELX_P50 50 GLY B 442 ? ALA B 446 ? GLY B 444 ALA B 448 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order covale1 covale ? ? A ASN 280 ND2 ? ? ? 1_555 H NAG . C1 ? ? A ASN 282 A NAG 1454 1_555 ? ? ? ? ? ? ? 1.435 ? metalc1 metalc ? ? A HIS 302 NE2 ? ? ? 1_555 L N7H . FE ? ? A HIS 304 A N7H 1458 1_555 ? ? ? ? ? ? ? 1.887 ? covale2 covale ? ? A ASN 347 ND2 ? ? ? 1_555 J NAG . C1 ? ? A ASN 349 A NAG 1455 1_555 ? ? ? ? ? ? ? 1.435 ? covale3 covale ? ? A ASN 413 ND2 ? ? ? 1_555 K NAG . C1 ? ? A ASN 415 A NAG 1456 1_555 ? ? ? ? ? ? ? 1.443 ? covale4 covale ? ? H NAG . O4 ? ? ? 1_555 I NAG . C1 ? ? A NAG 1454 A NAG 1457 1_555 ? ? ? ? ? ? ? 1.437 ? metalc2 metalc ? ? L N7H . FE ? ? ? 1_555 N NO2 . O1 ? ? A N7H 1458 A NO2 1460 1_555 ? ? ? ? ? ? ? 2.261 ? covale5 covale ? ? B ASN 280 ND2 ? ? ? 1_555 T NAG . C1 ? ? B ASN 282 B NAG 1454 1_555 ? ? ? ? ? ? ? 1.440 ? metalc3 metalc ? ? B HIS 302 NE2 ? ? ? 1_555 V N7H . FE ? ? B HIS 304 B N7H 1456 1_555 ? ? ? ? ? ? ? 1.880 ? covale6 covale ? ? B ASN 347 ND2 ? ? ? 1_555 U NAG . C1 ? ? B ASN 349 B NAG 1455 1_555 ? ? ? ? ? ? ? 1.438 ? metalc4 metalc ? ? V N7H . FE ? ? ? 1_555 W NO2 . O1 ? ? B N7H 1456 B NO2 1457 1_555 ? ? ? ? ? ? ? 2.341 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PRO 318 A . ? PRO 320 A PRO 319 A ? PRO 321 A 1 4.43 2 PHE 381 A . ? PHE 383 A PRO 382 A ? PRO 384 A 1 1.94 3 THR 386 A . ? THR 388 A PRO 387 A ? PRO 389 A 1 -3.28 4 ALA 286 B . ? ALA 288 B GLY 287 B ? GLY 289 B 1 -19.77 5 PRO 318 B . ? PRO 320 B PRO 319 B ? PRO 321 B 1 -0.84 6 PHE 381 B . ? PHE 383 B PRO 382 B ? PRO 384 B 1 5.89 7 THR 386 B . ? THR 388 B PRO 387 B ? PRO 389 B 1 -2.47 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA ? 4 ? AB ? 2 ? AC ? 2 ? AD ? 2 ? AE ? 4 ? AF ? 4 ? AG ? 2 ? BA ? 4 ? BB ? 2 ? BC ? 2 ? BD ? 2 ? BE ? 4 ? BF ? 4 ? BG ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA 1 2 ? anti-parallel AA 2 3 ? anti-parallel AA 3 4 ? anti-parallel AB 1 2 ? parallel AC 1 2 ? anti-parallel AD 1 2 ? parallel AE 1 2 ? anti-parallel AE 2 3 ? anti-parallel AE 3 4 ? parallel AF 1 2 ? anti-parallel AF 2 3 ? anti-parallel AF 3 4 ? anti-parallel AG 1 2 ? anti-parallel BA 1 2 ? anti-parallel BA 2 3 ? anti-parallel BA 3 4 ? anti-parallel BB 1 2 ? parallel BC 1 2 ? anti-parallel BD 1 2 ? parallel BE 1 2 ? anti-parallel BE 2 3 ? anti-parallel BE 3 4 ? parallel BF 1 2 ? anti-parallel BF 2 3 ? anti-parallel BF 3 4 ? anti-parallel BG 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA 1 ALA A 61 ? PHE A 66 ? ALA A 63 PHE A 68 AA 2 GLY A 114 ? SER A 120 ? GLY A 116 SER A 122 AA 3 LYS A 19 ? ILE A 27 ? LYS A 21 ILE A 29 AA 4 ILE A 141 ? SER A 150 ? ILE A 143 SER A 152 AB 1 ALA A 172 ? ILE A 173 ? ALA A 174 ILE A 175 AB 2 ILE A 185 ? VAL A 186 ? ILE A 187 VAL A 188 AC 1 MET A 329 ? ARG A 330 ? MET A 331 ARG A 332 AC 2 GLY A 354 ? GLN A 361 ? GLY A 356 GLN A 363 AD 1 ILE A 333 ? TYR A 335 ? ILE A 335 TYR A 337 AD 2 GLY A 354 ? GLN A 361 ? GLY A 356 GLN A 363 AE 1 VAL A 424 ? SER A 434 ? VAL A 426 SER A 436 AE 2 SER A 210 ? GLN A 219 ? SER A 212 GLN A 221 AE 3 GLY A 354 ? GLN A 361 ? GLY A 356 GLN A 363 AE 4 ILE A 333 ? TYR A 335 ? ILE A 335 TYR A 337 AF 1 VAL A 424 ? SER A 434 ? VAL A 426 SER A 436 AF 2 SER A 210 ? GLN A 219 ? SER A 212 GLN A 221 AF 3 GLY A 354 ? GLN A 361 ? GLY A 356 GLN A 363 AF 4 MET A 329 ? ARG A 330 ? MET A 331 ARG A 332 AG 1 ARG A 404 ? ASN A 407 ? ARG A 406 ASN A 409 AG 2 SER A 417 ? ILE A 420 ? SER A 419 ILE A 422 BA 1 VAL B 60 ? PHE B 66 ? VAL B 62 PHE B 68 BA 2 GLY B 114 ? SER B 120 ? GLY B 116 SER B 122 BA 3 LYS B 19 ? ILE B 27 ? LYS B 21 ILE B 29 BA 4 ILE B 141 ? SER B 150 ? ILE B 143 SER B 152 BB 1 ALA B 172 ? ILE B 173 ? ALA B 174 ILE B 175 BB 2 ILE B 185 ? VAL B 186 ? ILE B 187 VAL B 188 BC 1 MET B 329 ? ARG B 330 ? MET B 331 ARG B 332 BC 2 GLY B 354 ? GLN B 361 ? GLY B 356 GLN B 363 BD 1 ILE B 333 ? TYR B 335 ? ILE B 335 TYR B 337 BD 2 GLY B 354 ? GLN B 361 ? GLY B 356 GLN B 363 BE 1 VAL B 424 ? SER B 434 ? VAL B 426 SER B 436 BE 2 SER B 210 ? GLN B 219 ? SER B 212 GLN B 221 BE 3 GLY B 354 ? GLN B 361 ? GLY B 356 GLN B 363 BE 4 ILE B 333 ? TYR B 335 ? ILE B 335 TYR B 337 BF 1 VAL B 424 ? SER B 434 ? VAL B 426 SER B 436 BF 2 SER B 210 ? GLN B 219 ? SER B 212 GLN B 221 BF 3 GLY B 354 ? GLN B 361 ? GLY B 356 GLN B 363 BF 4 MET B 329 ? ARG B 330 ? MET B 331 ARG B 332 BG 1 ARG B 404 ? ASN B 407 ? ARG B 406 ASN B 409 BG 2 SER B 417 ? ILE B 420 ? SER B 419 ILE B 422 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA 1 2 N ALA A 65 ? N ALA A 67 O VAL A 115 ? O VAL A 117 AA 2 3 N SER A 120 ? N SER A 122 O LYS A 19 ? O LYS A 21 AA 3 4 N ALA A 26 ? N ALA A 28 O SER A 142 ? O SER A 144 AB 1 2 O ALA A 172 ? O ALA A 174 N VAL A 186 ? N VAL A 188 AC 1 2 N MET A 329 ? N MET A 331 O TYR A 360 ? O TYR A 362 AD 1 2 N TYR A 335 ? N TYR A 337 O GLY A 354 ? O GLY A 356 AE 1 2 N SER A 434 ? N SER A 436 O SER A 210 ? O SER A 212 AE 2 3 N LEU A 217 ? N LEU A 219 O LEU A 355 ? O LEU A 357 AE 3 4 N ALA A 356 ? N ALA A 358 O ILE A 333 ? O ILE A 335 AF 1 2 N SER A 434 ? N SER A 436 O SER A 210 ? O SER A 212 AF 2 3 N LEU A 217 ? N LEU A 219 O LEU A 355 ? O LEU A 357 AF 3 4 N TYR A 360 ? N TYR A 362 O MET A 329 ? O MET A 331 AG 1 2 N VAL A 406 ? N VAL A 408 O LEU A 418 ? O LEU A 420 BA 1 2 N ALA B 65 ? N ALA B 67 O VAL B 115 ? O VAL B 117 BA 2 3 N SER B 120 ? N SER B 122 O LYS B 19 ? O LYS B 21 BA 3 4 N ALA B 26 ? N ALA B 28 O SER B 142 ? O SER B 144 BB 1 2 O ALA B 172 ? O ALA B 174 N VAL B 186 ? N VAL B 188 BC 1 2 N MET B 329 ? N MET B 331 O TYR B 360 ? O TYR B 362 BD 1 2 N TYR B 335 ? N TYR B 337 O GLY B 354 ? O GLY B 356 BE 1 2 N SER B 434 ? N SER B 436 O SER B 210 ? O SER B 212 BE 2 3 N LEU B 217 ? N LEU B 219 O LEU B 355 ? O LEU B 357 BE 3 4 N ALA B 356 ? N ALA B 358 O ILE B 333 ? O ILE B 335 BF 1 2 N SER B 434 ? N SER B 436 O SER B 210 ? O SER B 212 BF 2 3 N LEU B 217 ? N LEU B 219 O LEU B 355 ? O LEU B 357 BF 3 4 N TYR B 360 ? N TYR B 362 O MET B 329 ? O MET B 331 BG 1 2 N VAL B 406 ? N VAL B 408 O LEU B 418 ? O LEU B 420 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE CAC A 1449' AC2 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE CAC B 1449' AC3 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE GOL A 1450' AC4 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE GOL B 1450' AC5 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE GOL A 1451' AC6 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE GOL B 1451' AC7 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE GOL B 1452' AC8 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE GOL B 1453' AC9 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE GOL A 1452' BC1 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE GOL A 1453' BC2 Software ? ? ? ? 24 'BINDING SITE FOR RESIDUE N7H A 1458' BC3 Software ? ? ? ? 25 'BINDING SITE FOR RESIDUE N7H B 1456' BC4 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE FMT A 1459' BC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NO2 A 1460' BC6 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NO2 B 1457' BC7 Software ? ? ? ? 6 'Binding site for Poly-Saccharide residues NAG A1454 through NAG A1457 bound to ASN A 282' BC8 Software ? ? ? ? 6 'Binding site for Mono-Saccharide NAG A1455 bound to ASN A 349' BC9 Software ? ? ? ? 7 'Binding site for Mono-Saccharide NAG A1456 bound to ASN A 415' CC1 Software ? ? ? ? 7 'Binding site for Mono-Saccharide NAG B1454 bound to ASN B 282' CC2 Software ? ? ? ? 5 'Binding site for Mono-Saccharide NAG B1455 bound to ASN B 349' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 SER A 284 ? SER A 286 . ? 1_555 ? 2 AC1 4 HIS A 285 ? HIS A 287 . ? 1_555 ? 3 AC1 4 ALA A 286 ? ALA A 288 . ? 1_555 ? 4 AC1 4 HOH X . ? HOH A 2375 . ? 1_555 ? 5 AC2 2 HIS B 285 ? HIS B 287 . ? 1_555 ? 6 AC2 2 ALA B 286 ? ALA B 288 . ? 1_555 ? 7 AC3 8 ASP A 124 ? ASP A 126 . ? 1_555 ? 8 AC3 8 GLN A 128 ? GLN A 130 . ? 1_555 ? 9 AC3 8 HOH X . ? HOH A 2218 . ? 1_555 ? 10 AC3 8 HOH X . ? HOH A 2474 . ? 1_555 ? 11 AC3 8 HOH X . ? HOH A 2475 . ? 1_555 ? 12 AC3 8 SER B 150 ? SER B 152 . ? 1_555 ? 13 AC3 8 PRO B 337 ? PRO B 339 . ? 1_555 ? 14 AC3 8 GOL S . ? GOL B 1453 . ? 1_555 ? 15 AC4 10 LYS A 19 ? LYS A 21 . ? 1_555 ? 16 AC4 10 SER A 150 ? SER A 152 . ? 1_555 ? 17 AC4 10 PRO A 337 ? PRO A 339 . ? 1_555 ? 18 AC4 10 GLU A 338 ? GLU A 340 . ? 1_555 ? 19 AC4 10 HOH X . ? HOH A 2244 . ? 1_555 ? 20 AC4 10 HOH X . ? HOH A 2410 . ? 1_555 ? 21 AC4 10 HOH X . ? HOH A 2412 . ? 1_555 ? 22 AC4 10 ASP B 124 ? ASP B 126 . ? 1_555 ? 23 AC4 10 ASP B 127 ? ASP B 129 . ? 1_555 ? 24 AC4 10 GLN B 128 ? GLN B 130 . ? 1_555 ? 25 AC5 8 ARG A 152 ? ARG A 154 . ? 1_555 ? 26 AC5 8 GLU A 156 ? GLU A 158 . ? 1_555 ? 27 AC5 8 PHE A 162 ? PHE A 164 . ? 1_555 ? 28 AC5 8 GLY A 163 ? GLY A 165 . ? 1_555 ? 29 AC5 8 ASN A 225 ? ASN A 227 . ? 1_555 ? 30 AC5 8 LYS A 255 ? LYS A 257 . ? 1_555 ? 31 AC5 8 HOH X . ? HOH A 2307 . ? 1_555 ? 32 AC5 8 HOH X . ? HOH A 2476 . ? 1_555 ? 33 AC6 5 ARG A 443 ? ARG A 445 . ? 1_645 ? 34 AC6 5 PRO B 199 ? PRO B 201 . ? 1_555 ? 35 AC6 5 ILE B 200 ? ILE B 202 . ? 1_555 ? 36 AC6 5 THR B 201 ? THR B 203 . ? 1_555 ? 37 AC6 5 HOH Y . ? HOH B 2407 . ? 1_555 ? 38 AC7 10 ARG B 249 ? ARG B 251 . ? 1_555 ? 39 AC7 10 SER B 292 ? SER B 294 . ? 1_555 ? 40 AC7 10 ASP B 293 ? ASP B 295 . ? 1_555 ? 41 AC7 10 GLN B 294 ? GLN B 296 . ? 1_555 ? 42 AC7 10 SER B 295 ? SER B 297 . ? 1_555 ? 43 AC7 10 GLY B 408 ? GLY B 410 . ? 1_555 ? 44 AC7 10 LEU B 410 ? LEU B 412 . ? 1_555 ? 45 AC7 10 PRO B 411 ? PRO B 413 . ? 1_555 ? 46 AC7 10 SER B 414 ? SER B 416 . ? 1_555 ? 47 AC7 10 HOH Y . ? HOH B 2317 . ? 1_555 ? 48 AC8 7 GOL D . ? GOL A 1450 . ? 1_555 ? 49 AC8 7 HOH X . ? HOH A 2211 . ? 1_555 ? 50 AC8 7 SER B 148 ? SER B 150 . ? 1_555 ? 51 AC8 7 SER B 150 ? SER B 152 . ? 1_555 ? 52 AC8 7 TYR B 335 ? TYR B 337 . ? 1_555 ? 53 AC8 7 GLY B 336 ? GLY B 338 . ? 1_555 ? 54 AC8 7 HOH Y . ? HOH B 2180 . ? 1_555 ? 55 AC9 4 ALA A 270 ? ALA A 272 . ? 1_555 ? 56 AC9 4 ASP A 274 ? ASP A 276 . ? 1_555 ? 57 AC9 4 ARG A 277 ? ARG A 279 . ? 1_555 ? 58 AC9 4 HOH X . ? HOH A 2358 . ? 1_555 ? 59 BC1 5 GLY A 194 ? GLY A 196 . ? 1_555 ? 60 BC1 5 ALA A 195 ? ALA A 197 . ? 1_555 ? 61 BC1 5 THR A 196 ? THR A 198 . ? 1_555 ? 62 BC1 5 ASN A 197 ? ASN A 199 . ? 1_555 ? 63 BC1 5 ASP A 198 ? ASP A 200 . ? 1_555 ? 64 BC2 24 GLU A 160 ? GLU A 162 . ? 1_555 ? 65 BC2 24 PHE A 164 ? PHE A 166 . ? 1_555 ? 66 BC2 24 LEU A 165 ? LEU A 167 . ? 1_555 ? 67 BC2 24 ASP A 166 ? ASP A 168 . ? 1_555 ? 68 BC2 24 GLY A 167 ? GLY A 169 . ? 1_555 ? 69 BC2 24 ILE A 168 ? ILE A 170 . ? 1_555 ? 70 BC2 24 ALA A 169 ? ALA A 171 . ? 1_555 ? 71 BC2 24 GLN A 219 ? GLN A 221 . ? 1_555 ? 72 BC2 24 VAL A 251 ? VAL A 253 . ? 1_555 ? 73 BC2 24 ARG A 253 ? ARG A 255 . ? 1_555 ? 74 BC2 24 HIS A 302 ? HIS A 304 . ? 1_555 ? 75 BC2 24 THR A 306 ? THR A 308 . ? 1_555 ? 76 BC2 24 ARG A 307 ? ARG A 309 . ? 1_555 ? 77 BC2 24 ARG A 309 ? ARG A 311 . ? 1_555 ? 78 BC2 24 ARG A 330 ? ARG A 332 . ? 1_555 ? 79 BC2 24 LEU A 355 ? LEU A 357 . ? 1_555 ? 80 BC2 24 PHE A 357 ? PHE A 359 . ? 1_555 ? 81 BC2 24 PHE A 368 ? PHE A 370 . ? 1_555 ? 82 BC2 24 ILE A 396 ? ILE A 398 . ? 1_555 ? 83 BC2 24 NO2 N . ? NO2 A 1460 . ? 1_555 ? 84 BC2 24 HOH X . ? HOH A 2339 . ? 1_555 ? 85 BC2 24 HOH X . ? HOH A 2365 . ? 1_555 ? 86 BC2 24 HOH X . ? HOH A 2372 . ? 1_555 ? 87 BC2 24 HOH X . ? HOH A 2483 . ? 1_555 ? 88 BC3 25 GLU B 160 ? GLU B 162 . ? 1_555 ? 89 BC3 25 PHE B 164 ? PHE B 166 . ? 1_555 ? 90 BC3 25 LEU B 165 ? LEU B 167 . ? 1_555 ? 91 BC3 25 ASP B 166 ? ASP B 168 . ? 1_555 ? 92 BC3 25 GLY B 167 ? GLY B 169 . ? 1_555 ? 93 BC3 25 ILE B 168 ? ILE B 170 . ? 1_555 ? 94 BC3 25 ALA B 169 ? ALA B 171 . ? 1_555 ? 95 BC3 25 LEU B 217 ? LEU B 219 . ? 1_555 ? 96 BC3 25 GLN B 219 ? GLN B 221 . ? 1_555 ? 97 BC3 25 VAL B 251 ? VAL B 253 . ? 1_555 ? 98 BC3 25 ARG B 253 ? ARG B 255 . ? 1_555 ? 99 BC3 25 HIS B 302 ? HIS B 304 . ? 1_555 ? 100 BC3 25 THR B 306 ? THR B 308 . ? 1_555 ? 101 BC3 25 ARG B 307 ? ARG B 309 . ? 1_555 ? 102 BC3 25 ARG B 309 ? ARG B 311 . ? 1_555 ? 103 BC3 25 ARG B 330 ? ARG B 332 . ? 1_555 ? 104 BC3 25 PHE B 357 ? PHE B 359 . ? 1_555 ? 105 BC3 25 PHE B 368 ? PHE B 370 . ? 1_555 ? 106 BC3 25 ILE B 396 ? ILE B 398 . ? 1_555 ? 107 BC3 25 VAL B 424 ? VAL B 426 . ? 1_555 ? 108 BC3 25 NO2 W . ? NO2 B 1457 . ? 1_555 ? 109 BC3 25 HOH Y . ? HOH B 2273 . ? 1_555 ? 110 BC3 25 HOH Y . ? HOH B 2302 . ? 1_555 ? 111 BC3 25 HOH Y . ? HOH B 2309 . ? 1_555 ? 112 BC3 25 HOH Y . ? HOH B 2409 . ? 1_555 ? 113 BC4 2 ASN A 28 ? ASN A 30 . ? 1_555 ? 114 BC4 2 SER A 139 ? SER A 141 . ? 1_555 ? 115 BC5 6 ASP A 166 ? ASP A 168 . ? 1_555 ? 116 BC5 6 ARG A 330 ? ARG A 332 . ? 1_555 ? 117 BC5 6 LEU A 355 ? LEU A 357 . ? 1_555 ? 118 BC5 6 PHE A 357 ? PHE A 359 . ? 1_555 ? 119 BC5 6 N7H L . ? N7H A 1458 . ? 1_555 ? 120 BC5 6 HOH X . ? HOH A 2259 . ? 1_555 ? 121 BC6 6 ASP B 166 ? ASP B 168 . ? 1_555 ? 122 BC6 6 ARG B 330 ? ARG B 332 . ? 1_555 ? 123 BC6 6 PHE B 357 ? PHE B 359 . ? 1_555 ? 124 BC6 6 N7H V . ? N7H B 1456 . ? 1_555 ? 125 BC6 6 HOH Y . ? HOH B 2201 . ? 1_555 ? 126 BC6 6 HOH Y . ? HOH B 2344 . ? 1_555 ? 127 BC7 6 GLN A 276 ? GLN A 278 . ? 1_555 ? 128 BC7 6 ASN A 280 ? ASN A 282 . ? 1_555 ? 129 BC7 6 PRO A 318 ? PRO A 320 . ? 1_555 ? 130 BC7 6 HOH X . ? HOH A 2367 . ? 1_555 ? 131 BC7 6 HOH X . ? HOH A 2477 . ? 1_555 ? 132 BC7 6 HOH X . ? HOH A 2478 . ? 1_555 ? 133 BC8 6 LYS A 226 ? LYS A 228 . ? 1_555 ? 134 BC8 6 ASP A 230 ? ASP A 232 . ? 1_555 ? 135 BC8 6 ALA A 345 ? ALA A 347 . ? 1_555 ? 136 BC8 6 ASN A 347 ? ASN A 349 . ? 1_555 ? 137 BC8 6 HOH X . ? HOH A 2309 . ? 1_555 ? 138 BC8 6 HOH X . ? HOH A 2479 . ? 1_555 ? 139 BC9 7 ASN A 413 ? ASN A 415 . ? 1_555 ? 140 BC9 7 SER A 415 ? SER A 417 . ? 1_555 ? 141 BC9 7 HOH X . ? HOH A 2459 . ? 1_555 ? 142 BC9 7 HOH X . ? HOH A 2463 . ? 1_555 ? 143 BC9 7 HOH X . ? HOH A 2480 . ? 1_555 ? 144 BC9 7 HOH X . ? HOH A 2481 . ? 1_555 ? 145 BC9 7 HOH X . ? HOH A 2482 . ? 1_555 ? 146 CC1 7 GLN B 276 ? GLN B 278 . ? 1_555 ? 147 CC1 7 ARG B 277 ? ARG B 279 . ? 1_555 ? 148 CC1 7 ASN B 280 ? ASN B 282 . ? 1_555 ? 149 CC1 7 PRO B 318 ? PRO B 320 . ? 1_555 ? 150 CC1 7 HOH Y . ? HOH B 2304 . ? 1_555 ? 151 CC1 7 HOH Y . ? HOH B 2306 . ? 1_555 ? 152 CC1 7 HOH Y . ? HOH B 2408 . ? 1_555 ? 153 CC2 5 LYS B 226 ? LYS B 228 . ? 1_555 ? 154 CC2 5 ASP B 230 ? ASP B 232 . ? 1_555 ? 155 CC2 5 ALA B 345 ? ALA B 347 . ? 1_555 ? 156 CC2 5 ASN B 347 ? ASN B 349 . ? 1_555 ? 157 CC2 5 HOH Y . ? HOH B 2352 . ? 1_555 ? # _database_PDB_matrix.entry_id 5AG1 _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 5AG1 _atom_sites.fract_transf_matrix[1][1] 0.015152 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.002816 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.021377 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.006866 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol AS C FE N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . SER A 1 1 ? 67.463 16.212 25.220 1.00 50.17 ? 3 SER A N 1 ATOM 2 C CA . SER A 1 1 ? 68.955 16.173 25.220 1.00 50.71 ? 3 SER A CA 1 ATOM 3 C C . SER A 1 1 ? 69.479 15.148 26.222 1.00 44.72 ? 3 SER A C 1 ATOM 4 O O . SER A 1 1 ? 68.910 14.973 27.300 1.00 46.68 ? 3 SER A O 1 ATOM 5 C CB . SER A 1 1 ? 69.527 17.557 25.532 1.00 51.50 ? 3 SER A CB 1 ATOM 6 O OG . SER A 1 1 ? 68.892 18.124 26.664 1.00 53.89 ? 3 SER A OG 1 ATOM 7 N N . LEU A 1 2 ? 70.571 14.480 25.861 1.00 37.51 ? 4 LEU A N 1 ATOM 8 C CA . LEU A 1 2 ? 71.069 13.346 26.633 1.00 32.20 ? 4 LEU A CA 1 ATOM 9 C C . LEU A 1 2 ? 71.763 13.794 27.914 1.00 29.15 ? 4 LEU A C 1 ATOM 10 O O . LEU A 1 2 ? 72.576 14.717 27.903 1.00 28.45 ? 4 LEU A O 1 ATOM 11 C CB . LEU A 1 2 ? 72.035 12.508 25.792 1.00 31.04 ? 4 LEU A CB 1 ATOM 12 C CG . LEU A 1 2 ? 71.451 11.734 24.610 1.00 29.28 ? 4 LEU A CG 1 ATOM 13 C CD1 . LEU A 1 2 ? 72.568 11.127 23.778 1.00 26.01 ? 4 LEU A CD1 1 ATOM 14 C CD2 . LEU A 1 2 ? 70.484 10.661 25.087 1.00 28.96 ? 4 LEU A CD2 1 ATOM 15 N N . ASN A 1 3 ? 71.456 13.116 29.014 1.00 24.97 ? 5 ASN A N 1 ATOM 16 C CA . ASN A 1 3 ? 72.227 13.266 30.238 1.00 22.73 ? 5 ASN A CA 1 ATOM 17 C C . ASN A 1 3 ? 73.383 12.271 30.278 1.00 21.18 ? 5 ASN A C 1 ATOM 18 O O . ASN A 1 3 ? 73.217 11.133 30.720 1.00 18.02 ? 5 ASN A O 1 ATOM 19 C CB . ASN A 1 3 ? 71.330 13.080 31.461 1.00 21.02 ? 5 ASN A CB 1 ATOM 20 C CG . ASN A 1 3 ? 72.084 13.243 32.765 1.00 22.95 ? 5 ASN A CG 1 ATOM 21 O OD1 . ASN A 1 3 ? 73.260 13.607 32.775 1.00 24.11 ? 5 ASN A OD1 1 ATOM 22 N ND2 . ASN A 1 3 ? 71.413 12.962 33.874 1.00 22.66 ? 5 ASN A ND2 1 ATOM 23 N N . THR A 1 4 ? 74.549 12.699 29.806 1.00 19.22 ? 6 THR A N 1 ATOM 24 C CA . THR A 1 4 ? 75.662 11.779 29.603 1.00 19.06 ? 6 THR A CA 1 ATOM 25 C C . THR A 1 4 ? 76.367 11.452 30.911 1.00 18.23 ? 6 THR A C 1 ATOM 26 O O . THR A 1 4 ? 77.210 10.559 30.962 1.00 17.00 ? 6 THR A O 1 ATOM 27 C CB . THR A 1 4 ? 76.679 12.318 28.579 1.00 20.61 ? 6 THR A CB 1 ATOM 28 O OG1 . THR A 1 4 ? 77.286 13.517 29.080 1.00 22.11 ? 6 THR A OG1 1 ATOM 29 C CG2 . THR A 1 4 ? 75.995 12.609 27.256 1.00 22.44 ? 6 THR A CG2 1 ATOM 30 N N . ASP A 1 5 ? 76.018 12.182 31.965 1.00 17.90 ? 7 ASP A N 1 ATOM 31 C CA . ASP A 1 5 ? 76.437 11.829 33.314 1.00 18.80 ? 7 ASP A CA 1 ATOM 32 C C . ASP A 1 5 ? 75.831 10.494 33.735 1.00 18.18 ? 7 ASP A C 1 ATOM 33 O O . ASP A 1 5 ? 76.359 9.816 34.615 1.00 19.09 ? 7 ASP A O 1 ATOM 34 C CB . ASP A 1 5 ? 76.004 12.907 34.311 1.00 20.76 ? 7 ASP A CB 1 ATOM 35 C CG . ASP A 1 5 ? 76.926 14.112 34.311 1.00 23.51 ? 7 ASP A CG 1 ATOM 36 O OD1 . ASP A 1 5 ? 77.974 14.072 33.634 1.00 22.35 ? 7 ASP A OD1 1 ATOM 37 O OD2 . ASP A 1 5 ? 76.600 15.102 34.999 1.00 25.30 ? 7 ASP A OD2 1 ATOM 38 N N . ASP A 1 6 ? 74.688 10.155 33.146 1.00 16.01 ? 8 ASP A N 1 ATOM 39 C CA . ASP A 1 6 ? 73.877 9.046 33.631 1.00 14.97 ? 8 ASP A CA 1 ATOM 40 C C . ASP A 1 6 ? 73.889 7.852 32.678 1.00 13.92 ? 8 ASP A C 1 ATOM 41 O O . ASP A 1 6 ? 73.290 6.820 32.963 1.00 14.71 ? 8 ASP A O 1 ATOM 42 C CB . ASP A 1 6 ? 72.435 9.502 33.875 1.00 15.36 ? 8 ASP A CB 1 ATOM 43 C CG . ASP A 1 6 ? 71.713 8.635 34.890 1.00 15.58 ? 8 ASP A CG 1 ATOM 44 O OD1 . ASP A 1 6 ? 72.368 8.153 35.839 1.00 15.83 ? 8 ASP A OD1 1 ATOM 45 O OD2 . ASP A 1 6 ? 70.485 8.451 34.753 1.00 16.39 ? 8 ASP A OD2 1 ATOM 46 N N . ILE A 1 7 ? 74.540 8.013 31.531 1.00 11.85 ? 9 ILE A N 1 ATOM 47 C CA . ILE A 1 7 ? 74.624 6.941 30.549 1.00 10.69 ? 9 ILE A CA 1 ATOM 48 C C . ILE A 1 7 ? 75.964 6.227 30.684 1.00 10.25 ? 9 ILE A C 1 ATOM 49 O O . ILE A 1 7 ? 77.006 6.873 30.793 1.00 10.16 ? 9 ILE A O 1 ATOM 50 C CB . ILE A 1 7 ? 74.476 7.483 29.115 1.00 10.74 ? 9 ILE A CB 1 ATOM 51 C CG1 . ILE A 1 7 ? 73.155 8.246 28.965 1.00 11.52 ? 9 ILE A CG1 1 ATOM 52 C CG2 . ILE A 1 7 ? 74.567 6.354 28.099 1.00 10.49 ? 9 ILE A CG2 1 ATOM 53 C CD1 . ILE A 1 7 ? 72.991 8.921 27.619 1.00 11.90 ? 9 ILE A CD1 1 ATOM 54 N N . GLN A 1 8 ? 75.934 4.898 30.685 1.00 9.73 ? 10 GLN A N 1 ATOM 55 C CA . GLN A 1 8 ? 77.159 4.112 30.816 1.00 9.85 ? 10 GLN A CA 1 ATOM 56 C C . GLN A 1 8 ? 78.078 4.295 29.609 1.00 10.15 ? 10 GLN A C 1 ATOM 57 O O . GLN A 1 8 ? 77.622 4.343 28.470 1.00 9.87 ? 10 GLN A O 1 ATOM 58 C CB . GLN A 1 8 ? 76.828 2.631 31.035 1.00 9.60 ? 10 GLN A CB 1 ATOM 59 C CG . GLN A 1 8 ? 76.088 2.369 32.338 1.00 9.80 ? 10 GLN A CG 1 ATOM 60 C CD . GLN A 1 8 ? 76.180 0.923 32.786 1.00 9.94 ? 10 GLN A CD 1 ATOM 61 O OE1 . GLN A 1 8 ? 77.268 0.354 32.865 1.00 9.52 ? 10 GLN A OE1 1 ATOM 62 N NE2 . GLN A 1 8 ? 75.034 0.320 33.082 1.00 9.99 ? 10 GLN A NE2 1 ATOM 63 N N . GLY A 1 9 ? 79.377 4.420 29.872 1.00 10.90 ? 11 GLY A N 1 ATOM 64 C CA . GLY A 1 9 ? 80.322 4.899 28.869 1.00 10.89 ? 11 GLY A CA 1 ATOM 65 C C . GLY A 1 9 ? 80.388 4.059 27.607 1.00 10.66 ? 11 GLY A C 1 ATOM 66 O O . GLY A 1 9 ? 80.483 4.594 26.506 1.00 11.76 ? 11 GLY A O 1 ATOM 67 N N . ASP A 1 10 ? 80.354 2.740 27.761 1.00 12.01 ? 12 ASP A N 1 ATOM 68 C CA . ASP A 1 10 ? 80.561 1.838 26.629 1.00 11.55 ? 12 ASP A CA 1 ATOM 69 C C . ASP A 1 10 ? 79.509 2.033 25.537 1.00 11.71 ? 12 ASP A C 1 ATOM 70 O O . ASP A 1 10 ? 79.776 1.788 24.360 1.00 11.55 ? 12 ASP A O 1 ATOM 71 C CB . ASP A 1 10 ? 80.577 0.376 27.090 1.00 11.96 ? 12 ASP A CB 1 ATOM 72 C CG . ASP A 1 10 ? 81.193 -0.558 26.053 1.00 11.98 ? 12 ASP A CG 1 ATOM 73 O OD1 . ASP A 1 10 ? 82.235 -0.199 25.466 1.00 12.16 ? 12 ASP A OD1 1 ATOM 74 O OD2 . ASP A 1 10 ? 80.640 -1.652 25.828 1.00 11.91 ? 12 ASP A OD2 1 ATOM 75 N N . ILE A 1 11 ? 78.313 2.465 25.933 1.00 11.82 ? 13 ILE A N 1 ATOM 76 C CA . ILE A 1 11 ? 77.189 2.576 25.005 1.00 11.84 ? 13 ILE A CA 1 ATOM 77 C C . ILE A 1 11 ? 77.472 3.563 23.874 1.00 12.35 ? 13 ILE A C 1 ATOM 78 O O . ILE A 1 11 ? 77.238 3.259 22.704 1.00 11.99 ? 13 ILE A O 1 ATOM 79 C CB . ILE A 1 11 ? 75.885 2.982 25.729 1.00 11.95 ? 13 ILE A CB 1 ATOM 80 C CG1 . ILE A 1 11 ? 75.558 1.990 26.845 1.00 11.89 ? 13 ILE A CG1 1 ATOM 81 C CG2 . ILE A 1 11 ? 74.729 3.059 24.746 1.00 11.91 ? 13 ILE A CG2 1 ATOM 82 C CD1 . ILE A 1 11 ? 74.542 2.504 27.845 1.00 12.04 ? 13 ILE A CD1 1 ATOM 83 N N . LEU A 1 12 ? 78.025 4.723 24.219 1.00 12.73 ? 14 LEU A N 1 ATOM 84 C CA . LEU A 1 12 ? 78.136 5.818 23.258 1.00 13.39 ? 14 LEU A CA 1 ATOM 85 C C . LEU A 1 12 ? 79.570 6.145 22.842 1.00 15.16 ? 14 LEU A C 1 ATOM 86 O O . LEU A 1 12 ? 79.796 6.675 21.755 1.00 15.16 ? 14 LEU A O 1 ATOM 87 C CB . LEU A 1 12 ? 77.429 7.070 23.781 1.00 12.53 ? 14 LEU A CB 1 ATOM 88 C CG . LEU A 1 12 ? 75.903 6.973 23.857 1.00 12.95 ? 14 LEU A CG 1 ATOM 89 C CD1 . LEU A 1 12 ? 75.305 8.235 24.467 1.00 13.82 ? 14 LEU A CD1 1 ATOM 90 C CD2 . LEU A 1 12 ? 75.317 6.706 22.477 1.00 12.44 ? 14 LEU A CD2 1 ATOM 91 N N . VAL A 1 13 ? 80.538 5.845 23.701 1.00 16.26 ? 15 VAL A N 1 ATOM 92 C CA . VAL A 1 13 ? 81.920 6.233 23.416 1.00 17.68 ? 15 VAL A CA 1 ATOM 93 C C . VAL A 1 13 ? 82.933 5.094 23.492 1.00 19.44 ? 15 VAL A C 1 ATOM 94 O O . VAL A 1 13 ? 84.071 5.239 23.043 1.00 21.54 ? 15 VAL A O 1 ATOM 95 C CB . VAL A 1 13 ? 82.384 7.422 24.281 1.00 17.04 ? 15 VAL A CB 1 ATOM 96 C CG1 . VAL A 1 13 ? 81.565 8.665 23.959 1.00 17.04 ? 15 VAL A CG1 1 ATOM 97 C CG2 . VAL A 1 13 ? 82.298 7.086 25.761 1.00 17.04 ? 15 VAL A CG2 1 ATOM 98 N N . GLY A 1 14 ? 82.518 3.956 24.038 1.00 19.05 ? 16 GLY A N 1 ATOM 99 C CA . GLY A 1 14 ? 83.429 2.832 24.234 1.00 20.35 ? 16 GLY A CA 1 ATOM 100 C C . GLY A 1 14 ? 84.326 3.021 25.444 1.00 20.67 ? 16 GLY A C 1 ATOM 101 O O . GLY A 1 14 ? 84.400 4.114 26.004 1.00 21.70 ? 16 GLY A O 1 ATOM 102 N N . MET A 1 15 ? 85.026 1.959 25.832 1.00 19.56 ? 17 MET A N 1 ATOM 103 C CA . MET A 1 15 ? 85.741 1.925 27.109 1.00 21.46 ? 17 MET A CA 1 ATOM 104 C C . MET A 1 15 ? 87.100 2.627 27.061 1.00 23.38 ? 17 MET A C 1 ATOM 105 O O . MET A 1 15 ? 87.626 3.043 28.094 1.00 25.20 ? 17 MET A O 1 ATOM 106 C CB . MET A 1 15 ? 85.908 0.482 27.596 1.00 20.51 ? 17 MET A CB 1 ATOM 107 C CG . MET A 1 15 ? 84.613 -0.187 28.032 1.00 22.10 ? 17 MET A CG 1 ATOM 108 S SD . MET A 1 15 ? 83.692 0.777 29.250 1.00 25.79 ? 17 MET A SD 1 ATOM 109 C CE . MET A 1 15 ? 83.816 -0.278 30.692 1.00 20.29 ? 17 MET A CE 1 ATOM 110 N N . HIS A 1 16 ? 87.672 2.736 25.867 1.00 24.03 ? 18 HIS A N 1 ATOM 111 C CA . HIS A 1 16 ? 88.927 3.465 25.675 1.00 26.57 ? 18 HIS A CA 1 ATOM 112 C C . HIS A 1 16 ? 90.123 2.800 26.356 1.00 24.00 ? 18 HIS A C 1 ATOM 113 O O . HIS A 1 16 ? 91.018 3.489 26.843 1.00 24.90 ? 18 HIS A O 1 ATOM 114 C CB . HIS A 1 16 ? 88.799 4.905 26.182 1.00 29.50 ? 18 HIS A CB 1 ATOM 115 C CG . HIS A 1 16 ? 87.862 5.751 25.378 1.00 35.56 ? 18 HIS A CG 1 ATOM 116 N ND1 . HIS A 1 16 ? 86.983 6.642 25.956 1.00 40.33 ? 18 HIS A ND1 1 ATOM 117 C CD2 . HIS A 1 16 ? 87.664 5.840 24.041 1.00 41.03 ? 18 HIS A CD2 1 ATOM 118 C CE1 . HIS A 1 16 ? 86.284 7.244 25.010 1.00 41.91 ? 18 HIS A CE1 1 ATOM 119 N NE2 . HIS A 1 16 ? 86.676 6.774 23.839 1.00 43.00 ? 18 HIS A NE2 1 ATOM 120 N N . LYS A 1 17 ? 90.138 1.471 26.402 1.00 20.28 ? 19 LYS A N 1 ATOM 121 C CA . LYS A 1 17 ? 91.198 0.760 27.116 1.00 18.80 ? 19 LYS A CA 1 ATOM 122 C C . LYS A 1 17 ? 91.787 -0.384 26.296 1.00 17.65 ? 19 LYS A C 1 ATOM 123 O O . LYS A 1 17 ? 91.110 -0.961 25.443 1.00 16.46 ? 19 LYS A O 1 ATOM 124 C CB . LYS A 1 17 ? 90.695 0.240 28.464 1.00 18.04 ? 19 LYS A CB 1 ATOM 125 C CG . LYS A 1 17 ? 90.300 1.329 29.448 1.00 19.67 ? 19 LYS A CG 1 ATOM 126 C CD . LYS A 1 17 ? 91.517 2.012 30.056 1.00 20.58 ? 19 LYS A CD 1 ATOM 127 C CE . LYS A 1 17 ? 91.125 2.856 31.263 1.00 21.16 ? 19 LYS A CE 1 ATOM 128 N NZ . LYS A 1 17 ? 92.240 3.725 31.737 1.00 21.56 ? 19 LYS A NZ 1 ATOM 129 N N . GLN A 1 18 ? 93.039 -0.726 26.590 1.00 16.60 ? 20 GLN A N 1 ATOM 130 C CA . GLN A 1 18 ? 93.744 -1.803 25.896 1.00 17.02 ? 20 GLN A CA 1 ATOM 131 C C . GLN A 1 18 ? 93.081 -3.157 26.112 1.00 14.87 ? 20 GLN A C 1 ATOM 132 O O . GLN A 1 18 ? 93.037 -3.988 25.203 1.00 13.56 ? 20 GLN A O 1 ATOM 133 C CB . GLN A 1 18 ? 95.201 -1.878 26.365 1.00 18.93 ? 20 GLN A CB 1 ATOM 134 C CG . GLN A 1 18 ? 96.142 -0.922 25.653 1.00 22.32 ? 20 GLN A CG 1 ATOM 135 C CD . GLN A 1 18 ? 96.299 -1.251 24.182 1.00 23.66 ? 20 GLN A CD 1 ATOM 136 O OE1 . GLN A 1 18 ? 96.653 -2.374 23.818 1.00 30.49 ? 20 GLN A OE1 1 ATOM 137 N NE2 . GLN A 1 18 ? 96.024 -0.276 23.327 1.00 23.75 ? 20 GLN A NE2 1 ATOM 138 N N . LYS A 1 19 ? 92.631 -3.398 27.339 1.00 13.76 ? 21 LYS A N 1 ATOM 139 C CA . LYS A 1 19 ? 92.151 -4.716 27.738 1.00 13.22 ? 21 LYS A CA 1 ATOM 140 C C . LYS A 1 19 ? 90.704 -4.646 28.223 1.00 12.62 ? 21 LYS A C 1 ATOM 141 O O . LYS A 1 19 ? 90.303 -3.677 28.869 1.00 12.00 ? 21 LYS A O 1 ATOM 142 C CB . LYS A 1 19 ? 93.037 -5.287 28.849 1.00 13.66 ? 21 LYS A CB 1 ATOM 143 C CG . LYS A 1 19 ? 94.521 -5.303 28.522 1.00 13.64 ? 21 LYS A CG 1 ATOM 144 C CD . LYS A 1 19 ? 94.824 -6.250 27.371 1.00 13.07 ? 21 LYS A CD 1 ATOM 145 C CE . LYS A 1 19 ? 96.315 -6.292 27.077 1.00 13.94 ? 21 LYS A CE 1 ATOM 146 N NZ . LYS A 1 19 ? 96.655 -7.394 26.137 1.00 15.34 ? 21 LYS A NZ 1 ATOM 147 N N . GLN A 1 20 ? 89.931 -5.685 27.921 1.00 12.47 ? 22 GLN A N 1 ATOM 148 C CA . GLN A 1 20 ? 88.601 -5.835 28.496 1.00 12.49 ? 22 GLN A CA 1 ATOM 149 C C . GLN A 1 20 ? 88.355 -7.244 29.008 1.00 12.54 ? 22 GLN A C 1 ATOM 150 O O . GLN A 1 20 ? 88.820 -8.224 28.423 1.00 12.69 ? 22 GLN A O 1 ATOM 151 C CB . GLN A 1 20 ? 87.519 -5.455 27.481 1.00 13.16 ? 22 GLN A CB 1 ATOM 152 C CG . GLN A 1 20 ? 87.250 -3.963 27.419 1.00 13.39 ? 22 GLN A CG 1 ATOM 153 C CD . GLN A 1 20 ? 86.167 -3.595 26.426 1.00 12.63 ? 22 GLN A CD 1 ATOM 154 O OE1 . GLN A 1 20 ? 85.112 -4.237 26.358 1.00 13.01 ? 22 GLN A OE1 1 ATOM 155 N NE2 . GLN A 1 20 ? 86.408 -2.538 25.671 1.00 12.75 ? 22 GLN A NE2 1 ATOM 156 N N . LEU A 1 21 ? 87.634 -7.330 30.120 1.00 11.30 ? 23 LEU A N 1 ATOM 157 C CA . LEU A 1 21 ? 87.099 -8.593 30.597 1.00 11.15 ? 23 LEU A CA 1 ATOM 158 C C . LEU A 1 21 ? 85.580 -8.520 30.632 1.00 11.48 ? 23 LEU A C 1 ATOM 159 O O . LEU A 1 21 ? 85.004 -7.583 31.190 1.00 10.82 ? 23 LEU A O 1 ATOM 160 C CB . LEU A 1 21 ? 87.638 -8.908 31.997 1.00 11.22 ? 23 LEU A CB 1 ATOM 161 C CG . LEU A 1 21 ? 87.129 -10.206 32.623 1.00 11.20 ? 23 LEU A CG 1 ATOM 162 C CD1 . LEU A 1 21 ? 87.736 -11.407 31.910 1.00 11.29 ? 23 LEU A CD1 1 ATOM 163 C CD2 . LEU A 1 21 ? 87.447 -10.241 34.113 1.00 11.49 ? 23 LEU A CD2 1 ATOM 164 N N . PHE A 1 22 ? 84.935 -9.501 30.012 1.00 10.87 ? 24 PHE A N 1 ATOM 165 C CA . PHE A 1 22 ? 83.511 -9.708 30.193 1.00 10.00 ? 24 PHE A CA 1 ATOM 166 C C . PHE A 1 22 ? 83.279 -10.791 31.241 1.00 10.44 ? 24 PHE A C 1 ATOM 167 O O . PHE A 1 22 ? 83.587 -11.965 31.020 1.00 10.22 ? 24 PHE A O 1 ATOM 168 C CB . PHE A 1 22 ? 82.846 -10.091 28.871 1.00 9.37 ? 24 PHE A CB 1 ATOM 169 C CG . PHE A 1 22 ? 83.016 -9.063 27.787 1.00 10.45 ? 24 PHE A CG 1 ATOM 170 C CD1 . PHE A 1 22 ? 84.125 -9.090 26.957 1.00 10.20 ? 24 PHE A CD1 1 ATOM 171 C CD2 . PHE A 1 22 ? 82.059 -8.075 27.589 1.00 9.87 ? 24 PHE A CD2 1 ATOM 172 C CE1 . PHE A 1 22 ? 84.284 -8.149 25.955 1.00 10.22 ? 24 PHE A CE1 1 ATOM 173 C CE2 . PHE A 1 22 ? 82.206 -7.141 26.582 1.00 9.47 ? 24 PHE A CE2 1 ATOM 174 C CZ . PHE A 1 22 ? 83.321 -7.176 25.763 1.00 9.95 ? 24 PHE A CZ 1 ATOM 175 N N . TYR A 1 23 ? 82.773 -10.371 32.394 1.00 10.04 ? 25 TYR A N 1 ATOM 176 C CA . TYR A 1 23 ? 82.627 -11.236 33.561 1.00 10.93 ? 25 TYR A CA 1 ATOM 177 C C . TYR A 1 23 ? 81.141 -11.548 33.734 1.00 10.61 ? 25 TYR A C 1 ATOM 178 O O . TYR A 1 23 ? 80.361 -10.681 34.114 1.00 10.44 ? 25 TYR A O 1 ATOM 179 C CB . TYR A 1 23 ? 83.167 -10.495 34.791 1.00 11.27 ? 25 TYR A CB 1 ATOM 180 C CG . TYR A 1 23 ? 83.146 -11.255 36.103 1.00 12.82 ? 25 TYR A CG 1 ATOM 181 C CD1 . TYR A 1 23 ? 82.012 -11.261 36.907 1.00 13.32 ? 25 TYR A CD1 1 ATOM 182 C CD2 . TYR A 1 23 ? 84.305 -11.840 36.607 1.00 13.33 ? 25 TYR A CD2 1 ATOM 183 C CE1 . TYR A 1 23 ? 82.016 -11.879 38.148 1.00 13.98 ? 25 TYR A CE1 1 ATOM 184 C CE2 . TYR A 1 23 ? 84.315 -12.469 37.840 1.00 13.85 ? 25 TYR A CE2 1 ATOM 185 C CZ . TYR A 1 23 ? 83.167 -12.494 38.603 1.00 14.70 ? 25 TYR A CZ 1 ATOM 186 O OH . TYR A 1 23 ? 83.178 -13.100 39.844 1.00 14.47 ? 25 TYR A OH 1 ATOM 187 N N . PHE A 1 24 ? 80.740 -12.759 33.360 1.00 10.73 ? 26 PHE A N 1 ATOM 188 C CA . PHE A 1 24 ? 79.332 -13.139 33.398 1.00 10.59 ? 26 PHE A CA 1 ATOM 189 C C . PHE A 1 24 ? 79.010 -13.835 34.715 1.00 11.26 ? 26 PHE A C 1 ATOM 190 O O . PHE A 1 24 ? 79.657 -14.817 35.084 1.00 10.99 ? 26 PHE A O 1 ATOM 191 C CB . PHE A 1 24 ? 78.985 -14.056 32.226 1.00 10.38 ? 26 PHE A CB 1 ATOM 192 C CG . PHE A 1 24 ? 79.294 -13.464 30.879 1.00 10.36 ? 26 PHE A CG 1 ATOM 193 C CD1 . PHE A 1 24 ? 78.392 -12.616 30.258 1.00 9.94 ? 26 PHE A CD1 1 ATOM 194 C CD2 . PHE A 1 24 ? 80.480 -13.767 30.230 1.00 10.50 ? 26 PHE A CD2 1 ATOM 195 C CE1 . PHE A 1 24 ? 78.665 -12.080 29.015 1.00 9.88 ? 26 PHE A CE1 1 ATOM 196 C CE2 . PHE A 1 24 ? 80.757 -13.240 28.983 1.00 10.01 ? 26 PHE A CE2 1 ATOM 197 C CZ . PHE A 1 24 ? 79.848 -12.394 28.375 1.00 10.44 ? 26 PHE A CZ 1 ATOM 198 N N . PHE A 1 25 ? 78.003 -13.324 35.414 1.00 11.48 ? 27 PHE A N 1 ATOM 199 C CA . PHE A 1 25 ? 77.756 -13.731 36.788 1.00 11.85 ? 27 PHE A CA 1 ATOM 200 C C . PHE A 1 25 ? 76.329 -14.208 37.025 1.00 11.91 ? 27 PHE A C 1 ATOM 201 O O . PHE A 1 25 ? 75.420 -13.911 36.250 1.00 10.67 ? 27 PHE A O 1 ATOM 202 C CB . PHE A 1 25 ? 78.101 -12.595 37.759 1.00 11.69 ? 27 PHE A CB 1 ATOM 203 C CG . PHE A 1 25 ? 77.230 -11.377 37.608 1.00 11.51 ? 27 PHE A CG 1 ATOM 204 C CD1 . PHE A 1 25 ? 76.024 -11.280 38.284 1.00 11.79 ? 27 PHE A CD1 1 ATOM 205 C CD2 . PHE A 1 25 ? 77.641 -10.307 36.822 1.00 11.70 ? 27 PHE A CD2 1 ATOM 206 C CE1 . PHE A 1 25 ? 75.231 -10.150 38.164 1.00 11.55 ? 27 PHE A CE1 1 ATOM 207 C CE2 . PHE A 1 25 ? 76.858 -9.175 36.698 1.00 11.43 ? 27 PHE A CE2 1 ATOM 208 C CZ . PHE A 1 25 ? 75.648 -9.097 37.369 1.00 12.21 ? 27 PHE A CZ 1 ATOM 209 N N . ALA A 1 26 ? 76.142 -14.940 38.118 1.00 12.87 ? 28 ALA A N 1 ATOM 210 C CA . ALA A 1 26 ? 74.813 -15.182 38.659 1.00 12.96 ? 28 ALA A CA 1 ATOM 211 C C . ALA A 1 26 ? 74.670 -14.485 40.008 1.00 13.49 ? 28 ALA A C 1 ATOM 212 O O . ALA A 1 26 ? 75.660 -14.240 40.702 1.00 12.15 ? 28 ALA A O 1 ATOM 213 C CB . ALA A 1 26 ? 74.560 -16.676 38.800 1.00 13.18 ? 28 ALA A CB 1 ATOM 214 N N . ILE A 1 27 ? 73.438 -14.126 40.352 1.00 14.41 ? 29 ILE A N 1 ATOM 215 C CA . ILE A 1 27 ? 73.148 -13.544 41.656 1.00 15.58 ? 29 ILE A CA 1 ATOM 216 C C . ILE A 1 27 ? 72.652 -14.635 42.600 1.00 16.93 ? 29 ILE A C 1 ATOM 217 O O . ILE A 1 27 ? 71.667 -15.312 42.314 1.00 17.78 ? 29 ILE A O 1 ATOM 218 C CB . ILE A 1 27 ? 72.083 -12.435 41.552 1.00 15.41 ? 29 ILE A CB 1 ATOM 219 C CG1 . ILE A 1 27 ? 72.558 -11.327 40.609 1.00 15.08 ? 29 ILE A CG1 1 ATOM 220 C CG2 . ILE A 1 27 ? 71.773 -11.868 42.930 1.00 15.82 ? 29 ILE A CG2 1 ATOM 221 C CD1 . ILE A 1 27 ? 71.436 -10.502 40.014 1.00 16.05 ? 29 ILE A CD1 1 ATOM 222 N N . ASN A 1 28 ? 73.376 -14.851 43.692 1.00 19.25 ? 30 ASN A N 1 ATOM 223 C CA . ASN A 1 28 ? 73.033 -15.925 44.616 1.00 22.21 ? 30 ASN A CA 1 ATOM 224 C C . ASN A 1 28 ? 72.151 -15.425 45.753 1.00 23.18 ? 30 ASN A C 1 ATOM 225 O O . ASN A 1 28 ? 71.211 -16.102 46.174 1.00 25.09 ? 30 ASN A O 1 ATOM 226 C CB . ASN A 1 28 ? 74.300 -16.570 45.180 1.00 23.02 ? 30 ASN A CB 1 ATOM 227 C CG . ASN A 1 28 ? 75.136 -17.245 44.111 1.00 22.84 ? 30 ASN A CG 1 ATOM 228 O OD1 . ASN A 1 28 ? 74.604 -17.840 43.174 1.00 25.34 ? 30 ASN A OD1 1 ATOM 229 N ND2 . ASN A 1 28 ? 76.453 -17.154 44.246 1.00 23.99 ? 30 ASN A ND2 1 ATOM 230 N N . ASP A 1 29 ? 72.466 -14.232 46.244 1.00 22.14 ? 31 ASP A N 1 ATOM 231 C CA . ASP A 1 29 ? 71.765 -13.649 47.379 1.00 22.25 ? 31 ASP A CA 1 ATOM 232 C C . ASP A 1 29 ? 71.407 -12.200 47.049 1.00 20.22 ? 31 ASP A C 1 ATOM 233 O O . ASP A 1 29 ? 72.250 -11.312 47.154 1.00 18.26 ? 31 ASP A O 1 ATOM 234 C CB . ASP A 1 29 ? 72.654 -13.715 48.623 1.00 23.45 ? 31 ASP A CB 1 ATOM 235 C CG . ASP A 1 29 ? 71.985 -13.143 49.858 1.00 26.86 ? 31 ASP A CG 1 ATOM 236 O OD1 . ASP A 1 29 ? 70.815 -12.716 49.771 1.00 28.02 ? 31 ASP A OD1 1 ATOM 237 O OD2 . ASP A 1 29 ? 72.640 -13.114 50.920 1.00 29.96 ? 31 ASP A OD2 1 ATOM 238 N N . PRO A 1 30 ? 70.169 -11.976 46.584 1.00 19.97 ? 32 PRO A N 1 ATOM 239 C CA . PRO A 1 30 ? 69.707 -10.671 46.115 1.00 18.55 ? 32 PRO A CA 1 ATOM 240 C C . PRO A 1 30 ? 69.988 -9.559 47.118 1.00 17.28 ? 32 PRO A C 1 ATOM 241 O O . PRO A 1 30 ? 70.494 -8.501 46.745 1.00 16.21 ? 32 PRO A O 1 ATOM 242 C CB . PRO A 1 30 ? 68.198 -10.866 45.975 1.00 19.05 ? 32 PRO A CB 1 ATOM 243 C CG . PRO A 1 30 ? 68.031 -12.314 45.694 1.00 21.43 ? 32 PRO A CG 1 ATOM 244 C CD . PRO A 1 30 ? 69.158 -13.030 46.386 1.00 19.64 ? 32 PRO A CD 1 ATOM 245 N N . ALA A 1 31 ? 69.642 -9.793 48.379 1.00 17.40 ? 33 ALA A N 1 ATOM 246 C CA . ALA A 1 31 ? 69.714 -8.753 49.397 1.00 16.87 ? 33 ALA A CA 1 ATOM 247 C C . ALA A 1 31 ? 71.145 -8.266 49.580 1.00 15.96 ? 33 ALA A C 1 ATOM 248 O O . ALA A 1 31 ? 71.407 -7.064 49.586 1.00 16.03 ? 33 ALA A O 1 ATOM 249 C CB . ALA A 1 31 ? 69.153 -9.260 50.717 1.00 17.24 ? 33 ALA A CB 1 ATOM 250 N N . THR A 1 32 ? 72.068 -9.209 49.733 1.00 15.64 ? 34 THR A N 1 ATOM 251 C CA . THR A 1 32 ? 73.475 -8.883 49.906 1.00 15.12 ? 34 THR A CA 1 ATOM 252 C C . THR A 1 32 ? 74.047 -8.296 48.622 1.00 14.27 ? 34 THR A C 1 ATOM 253 O O . THR A 1 32 ? 74.813 -7.330 48.655 1.00 13.56 ? 34 THR A O 1 ATOM 254 C CB . THR A 1 32 ? 74.287 -10.126 50.316 1.00 15.93 ? 34 THR A CB 1 ATOM 255 O OG1 . THR A 1 32 ? 73.911 -10.526 51.639 1.00 15.70 ? 34 THR A OG1 1 ATOM 256 C CG2 . THR A 1 32 ? 75.777 -9.828 50.287 1.00 15.26 ? 34 THR A CG2 1 ATOM 257 N N . PHE A 1 33 ? 73.657 -8.873 47.489 1.00 14.18 ? 35 PHE A N 1 ATOM 258 C CA . PHE A 1 33 ? 74.082 -8.365 46.188 1.00 13.96 ? 35 PHE A CA 1 ATOM 259 C C . PHE A 1 33 ? 73.713 -6.890 46.045 1.00 14.11 ? 35 PHE A C 1 ATOM 260 O O . PHE A 1 33 ? 74.542 -6.065 45.654 1.00 13.36 ? 35 PHE A O 1 ATOM 261 C CB . PHE A 1 33 ? 73.442 -9.182 45.064 1.00 14.36 ? 35 PHE A CB 1 ATOM 262 C CG . PHE A 1 33 ? 73.958 -8.845 43.693 1.00 14.08 ? 35 PHE A CG 1 ATOM 263 C CD1 . PHE A 1 33 ? 73.377 -7.830 42.949 1.00 14.70 ? 35 PHE A CD1 1 ATOM 264 C CD2 . PHE A 1 33 ? 75.010 -9.558 43.139 1.00 14.68 ? 35 PHE A CD2 1 ATOM 265 C CE1 . PHE A 1 33 ? 73.846 -7.517 41.688 1.00 14.79 ? 35 PHE A CE1 1 ATOM 266 C CE2 . PHE A 1 33 ? 75.487 -9.250 41.877 1.00 15.58 ? 35 PHE A CE2 1 ATOM 267 C CZ . PHE A 1 33 ? 74.901 -8.230 41.148 1.00 15.69 ? 35 PHE A CZ 1 ATOM 268 N N . LYS A 1 34 ? 72.469 -6.564 46.388 1.00 14.10 ? 36 LYS A N 1 ATOM 269 C CA . LYS A 1 34 ? 71.963 -5.203 46.250 1.00 14.20 ? 36 LYS A CA 1 ATOM 270 C C . LYS A 1 34 ? 72.765 -4.229 47.108 1.00 14.74 ? 36 LYS A C 1 ATOM 271 O O . LYS A 1 34 ? 73.115 -3.136 46.661 1.00 14.00 ? 36 LYS A O 1 ATOM 272 C CB . LYS A 1 34 ? 70.484 -5.144 46.639 1.00 15.48 ? 36 LYS A CB 1 ATOM 273 C CG . LYS A 1 34 ? 69.533 -5.650 45.567 1.00 16.45 ? 36 LYS A CG 1 ATOM 274 C CD . LYS A 1 34 ? 68.130 -5.819 46.132 1.00 18.21 ? 36 LYS A CD 1 ATOM 275 C CE . LYS A 1 34 ? 67.125 -6.185 45.054 1.00 19.20 ? 36 LYS A CE 1 ATOM 276 N NZ . LYS A 1 34 ? 66.742 -5.005 44.230 1.00 18.95 ? 36 LYS A NZ 1 ATOM 277 N N . THR A 1 35 ? 73.047 -4.626 48.345 1.00 14.85 ? 37 THR A N 1 ATOM 278 C CA . THR A 1 35 ? 73.813 -3.785 49.257 1.00 15.82 ? 37 THR A CA 1 ATOM 279 C C . THR A 1 35 ? 75.122 -3.356 48.612 1.00 14.84 ? 37 THR A C 1 ATOM 280 O O . THR A 1 35 ? 75.497 -2.186 48.655 1.00 15.49 ? 37 THR A O 1 ATOM 281 C CB . THR A 1 35 ? 74.126 -4.519 50.575 1.00 17.98 ? 37 THR A CB 1 ATOM 282 O OG1 . THR A 1 35 ? 72.906 -4.801 51.269 1.00 18.77 ? 37 THR A OG1 1 ATOM 283 C CG2 . THR A 1 35 ? 75.026 -3.666 51.459 1.00 17.53 ? 37 THR A CG2 1 ATOM 284 N N . HIS A 1 36 ? 75.803 -4.309 47.986 1.00 14.99 ? 38 HIS A N 1 ATOM 285 C CA . HIS A 1 36 ? 77.117 -4.055 47.418 1.00 15.18 ? 38 HIS A CA 1 ATOM 286 C C . HIS A 1 36 ? 77.041 -3.448 46.023 1.00 14.76 ? 38 HIS A C 1 ATOM 287 O O . HIS A 1 36 ? 77.922 -2.688 45.621 1.00 15.42 ? 38 HIS A O 1 ATOM 288 C CB . HIS A 1 36 ? 77.946 -5.337 47.413 1.00 15.62 ? 38 HIS A CB 1 ATOM 289 C CG . HIS A 1 36 ? 78.365 -5.777 48.780 1.00 16.45 ? 38 HIS A CG 1 ATOM 290 N ND1 . HIS A 1 36 ? 79.262 -5.065 49.545 1.00 17.00 ? 38 HIS A ND1 1 ATOM 291 C CD2 . HIS A 1 36 ? 77.949 -6.809 49.550 1.00 16.74 ? 38 HIS A CD2 1 ATOM 292 C CE1 . HIS A 1 36 ? 79.410 -5.660 50.715 1.00 18.50 ? 38 HIS A CE1 1 ATOM 293 N NE2 . HIS A 1 36 ? 78.628 -6.724 50.742 1.00 16.82 ? 38 HIS A NE2 1 ATOM 294 N N . LEU A 1 37 ? 75.977 -3.769 45.294 1.00 14.13 ? 39 LEU A N 1 ATOM 295 C CA . LEU A 1 37 ? 75.710 -3.110 44.022 1.00 13.82 ? 39 LEU A CA 1 ATOM 296 C C . LEU A 1 37 ? 75.648 -1.598 44.222 1.00 14.21 ? 39 LEU A C 1 ATOM 297 O O . LEU A 1 37 ? 76.222 -0.834 43.446 1.00 13.87 ? 39 LEU A O 1 ATOM 298 C CB . LEU A 1 37 ? 74.405 -3.622 43.415 1.00 14.11 ? 39 LEU A CB 1 ATOM 299 C CG . LEU A 1 37 ? 74.044 -3.101 42.022 1.00 14.44 ? 39 LEU A CG 1 ATOM 300 C CD1 . LEU A 1 37 ? 75.100 -3.516 41.006 1.00 14.66 ? 39 LEU A CD1 1 ATOM 301 C CD2 . LEU A 1 37 ? 72.668 -3.598 41.606 1.00 13.65 ? 39 LEU A CD2 1 ATOM 302 N N . ALA A 1 38 ? 74.994 -1.176 45.300 1.00 13.72 ? 40 ALA A N 1 ATOM 303 C CA . ALA A 1 38 ? 74.841 0.243 45.587 1.00 15.60 ? 40 ALA A CA 1 ATOM 304 C C . ALA A 1 38 ? 76.129 0.869 46.128 1.00 16.83 ? 40 ALA A C 1 ATOM 305 O O . ALA A 1 38 ? 76.488 1.986 45.757 1.00 18.12 ? 40 ALA A O 1 ATOM 306 C CB . ALA A 1 38 ? 73.687 0.469 46.553 1.00 15.83 ? 40 ALA A CB 1 ATOM 307 N N A SER A 1 39 ? 76.822 0.141 46.998 0.50 17.53 ? 41 SER A N 1 ATOM 308 N N B SER A 1 39 ? 76.826 0.134 46.990 0.50 17.38 ? 41 SER A N 1 ATOM 309 C CA A SER A 1 39 ? 77.956 0.700 47.727 0.50 18.05 ? 41 SER A CA 1 ATOM 310 C CA B SER A 1 39 ? 77.953 0.690 47.732 0.50 17.84 ? 41 SER A CA 1 ATOM 311 C C A SER A 1 39 ? 79.258 0.602 46.939 0.50 18.35 ? 41 SER A C 1 ATOM 312 C C B SER A 1 39 ? 79.260 0.594 46.952 0.50 18.23 ? 41 SER A C 1 ATOM 313 O O A SER A 1 39 ? 80.086 1.510 46.981 0.50 18.93 ? 41 SER A O 1 ATOM 314 O O B SER A 1 39 ? 80.093 1.497 47.010 0.50 18.83 ? 41 SER A O 1 ATOM 315 C CB A SER A 1 39 ? 78.114 0.013 49.086 0.50 19.45 ? 41 SER A CB 1 ATOM 316 C CB B SER A 1 39 ? 78.101 -0.010 49.086 0.50 18.95 ? 41 SER A CB 1 ATOM 317 O OG A SER A 1 39 ? 77.010 0.288 49.929 0.50 19.69 ? 41 SER A OG 1 ATOM 318 O OG B SER A 1 39 ? 78.591 -1.331 48.926 0.50 19.10 ? 41 SER A OG 1 ATOM 319 N N . ASP A 1 40 ? 79.445 -0.513 46.241 1.00 18.38 ? 42 ASP A N 1 ATOM 320 C CA . ASP A 1 40 ? 80.734 -0.825 45.639 1.00 19.54 ? 42 ASP A CA 1 ATOM 321 C C . ASP A 1 40 ? 80.760 -0.596 44.133 1.00 19.28 ? 42 ASP A C 1 ATOM 322 O O . ASP A 1 40 ? 81.780 -0.189 43.580 1.00 20.06 ? 42 ASP A O 1 ATOM 323 C CB . ASP A 1 40 ? 81.142 -2.263 45.956 1.00 21.22 ? 42 ASP A CB 1 ATOM 324 C CG . ASP A 1 40 ? 81.385 -2.485 47.436 1.00 24.67 ? 42 ASP A CG 1 ATOM 325 O OD1 . ASP A 1 40 ? 81.807 -1.530 48.122 1.00 26.15 ? 42 ASP A OD1 1 ATOM 326 O OD2 . ASP A 1 40 ? 81.159 -3.617 47.910 1.00 27.18 ? 42 ASP A OD2 1 ATOM 327 N N . ILE A 1 41 ? 79.645 -0.874 43.469 1.00 17.20 ? 43 ILE A N 1 ATOM 328 C CA . ILE A 1 41 ? 79.616 -0.827 42.014 1.00 16.15 ? 43 ILE A CA 1 ATOM 329 C C . ILE A 1 41 ? 79.141 0.530 41.502 1.00 15.17 ? 43 ILE A C 1 ATOM 330 O O . ILE A 1 41 ? 79.844 1.193 40.744 1.00 15.32 ? 43 ILE A O 1 ATOM 331 C CB . ILE A 1 41 ? 78.745 -1.951 41.423 1.00 16.02 ? 43 ILE A CB 1 ATOM 332 C CG1 . ILE A 1 41 ? 79.296 -3.324 41.824 1.00 16.94 ? 43 ILE A CG1 1 ATOM 333 C CG2 . ILE A 1 41 ? 78.667 -1.822 39.910 1.00 15.51 ? 43 ILE A CG2 1 ATOM 334 C CD1 . ILE A 1 41 ? 80.653 -3.649 41.235 1.00 17.44 ? 43 ILE A CD1 1 ATOM 335 N N . ALA A 1 42 ? 77.971 0.959 41.961 1.00 15.28 ? 44 ALA A N 1 ATOM 336 C CA . ALA A 1 42 ? 77.347 2.180 41.457 1.00 16.47 ? 44 ALA A CA 1 ATOM 337 C C . ALA A 1 42 ? 78.308 3.367 41.392 1.00 16.19 ? 44 ALA A C 1 ATOM 338 O O . ALA A 1 42 ? 78.376 4.051 40.373 1.00 15.61 ? 44 ALA A O 1 ATOM 339 C CB . ALA A 1 42 ? 76.114 2.531 42.275 1.00 16.96 ? 44 ALA A CB 1 ATOM 340 N N . PRO A 1 43 ? 79.048 3.622 42.484 1.00 16.69 ? 45 PRO A N 1 ATOM 341 C CA . PRO A 1 43 ? 79.906 4.804 42.539 1.00 18.13 ? 45 PRO A CA 1 ATOM 342 C C . PRO A 1 43 ? 81.048 4.783 41.529 1.00 17.21 ? 45 PRO A C 1 ATOM 343 O O . PRO A 1 43 ? 81.647 5.822 41.266 1.00 20.73 ? 45 PRO A O 1 ATOM 344 C CB . PRO A 1 43 ? 80.468 4.765 43.965 1.00 18.33 ? 45 PRO A CB 1 ATOM 345 C CG . PRO A 1 43 ? 79.453 4.004 44.746 1.00 17.75 ? 45 PRO A CG 1 ATOM 346 C CD . PRO A 1 43 ? 78.928 2.965 43.796 1.00 17.10 ? 45 PRO A CD 1 ATOM 347 N N . VAL A 1 44 ? 81.376 3.612 40.991 1.00 17.14 ? 46 VAL A N 1 ATOM 348 C CA . VAL A 1 44 ? 82.540 3.493 40.111 1.00 16.36 ? 46 VAL A CA 1 ATOM 349 C C . VAL A 1 44 ? 82.177 3.102 38.684 1.00 15.74 ? 46 VAL A C 1 ATOM 350 O O . VAL A 1 44 ? 83.045 2.730 37.895 1.00 16.22 ? 46 VAL A O 1 ATOM 351 C CB . VAL A 1 44 ? 83.587 2.502 40.656 1.00 16.73 ? 46 VAL A CB 1 ATOM 352 C CG1 . VAL A 1 44 ? 84.158 2.997 41.978 1.00 17.16 ? 46 VAL A CG1 1 ATOM 353 C CG2 . VAL A 1 44 ? 82.990 1.112 40.803 1.00 16.69 ? 46 VAL A CG2 1 ATOM 354 N N . VAL A 1 45 ? 80.890 3.157 38.361 1.00 14.88 ? 47 VAL A N 1 ATOM 355 C CA . VAL A 1 45 ? 80.449 2.922 36.988 1.00 13.97 ? 47 VAL A CA 1 ATOM 356 C C . VAL A 1 45 ? 80.782 4.134 36.129 1.00 14.05 ? 47 VAL A C 1 ATOM 357 O O . VAL A 1 45 ? 80.374 5.254 36.439 1.00 14.83 ? 47 VAL A O 1 ATOM 358 C CB . VAL A 1 45 ? 78.934 2.651 36.913 1.00 13.50 ? 47 VAL A CB 1 ATOM 359 C CG1 . VAL A 1 45 ? 78.488 2.511 35.463 1.00 12.61 ? 47 VAL A CG1 1 ATOM 360 C CG2 . VAL A 1 45 ? 78.582 1.407 37.713 1.00 14.36 ? 47 VAL A CG2 1 ATOM 361 N N . ALA A 1 46 ? 81.519 3.907 35.047 1.00 12.97 ? 48 ALA A N 1 ATOM 362 C CA . ALA A 1 46 ? 82.031 5.001 34.229 1.00 13.17 ? 48 ALA A CA 1 ATOM 363 C C . ALA A 1 46 ? 80.972 5.520 33.262 1.00 12.67 ? 48 ALA A C 1 ATOM 364 O O . ALA A 1 46 ? 80.358 4.747 32.524 1.00 11.51 ? 48 ALA A O 1 ATOM 365 C CB . ALA A 1 46 ? 83.273 4.560 33.468 1.00 12.38 ? 48 ALA A CB 1 ATOM 366 N N . SER A 1 47 ? 80.775 6.834 33.263 1.00 12.57 ? 49 SER A N 1 ATOM 367 C CA . SER A 1 47 ? 79.751 7.460 32.436 1.00 12.51 ? 49 SER A CA 1 ATOM 368 C C . SER A 1 47 ? 80.340 7.901 31.107 1.00 12.92 ? 49 SER A C 1 ATOM 369 O O . SER A 1 47 ? 81.558 7.927 30.935 1.00 13.86 ? 49 SER A O 1 ATOM 370 C CB . SER A 1 47 ? 79.151 8.669 33.154 1.00 12.71 ? 49 SER A CB 1 ATOM 371 O OG . SER A 1 47 ? 80.114 9.699 33.282 1.00 13.76 ? 49 SER A OG 1 ATOM 372 N N . VAL A 1 48 ? 79.470 8.261 30.172 1.00 12.84 ? 50 VAL A N 1 ATOM 373 C CA . VAL A 1 48 ? 79.910 8.858 28.920 1.00 13.48 ? 50 VAL A CA 1 ATOM 374 C C . VAL A 1 48 ? 80.687 10.145 29.184 1.00 14.00 ? 50 VAL A C 1 ATOM 375 O O . VAL A 1 48 ? 81.773 10.353 28.638 1.00 14.36 ? 50 VAL A O 1 ATOM 376 C CB . VAL A 1 48 ? 78.720 9.141 27.986 1.00 13.92 ? 50 VAL A CB 1 ATOM 377 C CG1 . VAL A 1 48 ? 79.161 9.980 26.799 1.00 13.22 ? 50 VAL A CG1 1 ATOM 378 C CG2 . VAL A 1 48 ? 78.091 7.834 27.521 1.00 13.27 ? 50 VAL A CG2 1 ATOM 379 N N . THR A 1 49 ? 80.153 10.989 30.058 1.00 14.47 ? 51 THR A N 1 ATOM 380 C CA . THR A 1 49 ? 80.855 12.206 30.449 1.00 15.80 ? 51 THR A CA 1 ATOM 381 C C . THR A 1 49 ? 82.280 11.879 30.891 1.00 16.21 ? 51 THR A C 1 ATOM 382 O O . THR A 1 49 ? 83.248 12.490 30.433 1.00 15.94 ? 51 THR A O 1 ATOM 383 C CB . THR A 1 49 ? 80.130 12.935 31.596 1.00 16.55 ? 51 THR A CB 1 ATOM 384 O OG1 . THR A 1 49 ? 78.786 13.237 31.199 1.00 18.34 ? 51 THR A OG1 1 ATOM 385 C CG2 . THR A 1 49 ? 80.854 14.229 31.948 1.00 17.24 ? 51 THR A CG2 1 ATOM 386 N N . GLN A 1 50 ? 82.396 10.905 31.785 1.00 16.22 ? 52 GLN A N 1 ATOM 387 C CA . GLN A 1 50 ? 83.665 10.578 32.415 1.00 17.55 ? 52 GLN A CA 1 ATOM 388 C C . GLN A 1 50 ? 84.691 10.113 31.385 1.00 17.99 ? 52 GLN A C 1 ATOM 389 O O . GLN A 1 50 ? 85.842 10.559 31.395 1.00 16.96 ? 52 GLN A O 1 ATOM 390 C CB . GLN A 1 50 ? 83.448 9.492 33.462 1.00 19.96 ? 52 GLN A CB 1 ATOM 391 C CG . GLN A 1 50 ? 84.585 9.318 34.448 1.00 23.97 ? 52 GLN A CG 1 ATOM 392 C CD . GLN A 1 50 ? 84.292 8.221 35.448 1.00 29.19 ? 52 GLN A CD 1 ATOM 393 O OE1 . GLN A 1 50 ? 83.138 7.821 35.621 1.00 31.25 ? 52 GLN A OE1 1 ATOM 394 N NE2 . GLN A 1 50 ? 85.332 7.717 36.102 1.00 31.12 ? 52 GLN A NE2 1 ATOM 395 N N . LEU A 1 51 ? 84.258 9.234 30.483 1.00 16.93 ? 53 LEU A N 1 ATOM 396 C CA . LEU A 1 51 ? 85.148 8.630 29.499 1.00 17.02 ? 53 LEU A CA 1 ATOM 397 C C . LEU A 1 51 ? 85.450 9.571 28.337 1.00 17.82 ? 53 LEU A C 1 ATOM 398 O O . LEU A 1 51 ? 86.390 9.345 27.579 1.00 19.03 ? 53 LEU A O 1 ATOM 399 C CB . LEU A 1 51 ? 84.562 7.316 28.971 1.00 17.21 ? 53 LEU A CB 1 ATOM 400 C CG . LEU A 1 51 ? 84.447 6.159 29.967 1.00 17.36 ? 53 LEU A CG 1 ATOM 401 C CD1 . LEU A 1 51 ? 84.031 4.871 29.269 1.00 17.15 ? 53 LEU A CD1 1 ATOM 402 C CD2 . LEU A 1 51 ? 85.755 5.959 30.716 1.00 18.93 ? 53 LEU A CD2 1 ATOM 403 N N . SER A 1 52 ? 84.638 10.612 28.184 1.00 17.16 ? 54 SER A N 1 ATOM 404 C CA . SER A 1 52 ? 84.830 11.572 27.098 1.00 19.23 ? 54 SER A CA 1 ATOM 405 C C . SER A 1 52 ? 85.878 12.628 27.447 1.00 20.00 ? 54 SER A C 1 ATOM 406 O O . SER A 1 52 ? 86.278 13.419 26.596 1.00 21.18 ? 54 SER A O 1 ATOM 407 C CB . SER A 1 52 ? 83.507 12.250 26.738 1.00 18.33 ? 54 SER A CB 1 ATOM 408 O OG . SER A 1 52 ? 82.552 11.300 26.302 1.00 19.17 ? 54 SER A OG 1 ATOM 409 N N . ASN A 1 53 ? 86.310 12.641 28.703 1.00 20.45 ? 55 ASN A N 1 ATOM 410 C CA . ASN A 1 53 ? 87.297 13.611 29.170 1.00 21.66 ? 55 ASN A CA 1 ATOM 411 C C . ASN A 1 53 ? 88.658 12.949 29.382 1.00 20.72 ? 55 ASN A C 1 ATOM 412 O O . ASN A 1 53 ? 88.794 12.057 30.218 1.00 22.13 ? 55 ASN A O 1 ATOM 413 C CB . ASN A 1 53 ? 86.811 14.260 30.469 1.00 21.23 ? 55 ASN A CB 1 ATOM 414 C CG . ASN A 1 53 ? 87.688 15.416 30.915 1.00 23.12 ? 55 ASN A CG 1 ATOM 415 O OD1 . ASN A 1 53 ? 88.895 15.428 30.674 1.00 22.75 ? 55 ASN A OD1 1 ATOM 416 N ND2 . ASN A 1 53 ? 87.086 16.381 31.602 1.00 23.08 ? 55 ASN A ND2 1 ATOM 417 N N . VAL A 1 54 ? 89.659 13.384 28.622 1.00 20.92 ? 56 VAL A N 1 ATOM 418 C CA . VAL A 1 54 ? 90.984 12.769 28.682 1.00 20.38 ? 56 VAL A CA 1 ATOM 419 C C . VAL A 1 54 ? 91.606 12.893 30.069 1.00 19.81 ? 56 VAL A C 1 ATOM 420 O O . VAL A 1 54 ? 92.488 12.118 30.434 1.00 21.86 ? 56 VAL A O 1 ATOM 421 C CB . VAL A 1 54 ? 91.951 13.370 27.640 1.00 22.02 ? 56 VAL A CB 1 ATOM 422 C CG1 . VAL A 1 54 ? 91.481 13.056 26.227 1.00 21.93 ? 56 VAL A CG1 1 ATOM 423 C CG2 . VAL A 1 54 ? 92.094 14.870 27.846 1.00 20.71 ? 56 VAL A CG2 1 ATOM 424 N N . ALA A 1 55 ? 91.128 13.854 30.851 1.00 19.01 ? 57 ALA A N 1 ATOM 425 C CA . ALA A 1 55 ? 91.712 14.127 32.157 1.00 18.41 ? 57 ALA A CA 1 ATOM 426 C C . ALA A 1 55 ? 91.040 13.335 33.275 1.00 18.15 ? 57 ALA A C 1 ATOM 427 O O . ALA A 1 55 ? 91.473 13.399 34.423 1.00 18.80 ? 57 ALA A O 1 ATOM 428 C CB . ALA A 1 55 ? 91.669 15.619 32.458 1.00 18.34 ? 57 ALA A CB 1 ATOM 429 N N . THR A 1 56 ? 89.970 12.614 32.947 1.00 19.16 ? 58 THR A N 1 ATOM 430 C CA . THR A 1 56 ? 89.196 11.892 33.960 1.00 19.38 ? 58 THR A CA 1 ATOM 431 C C . THR A 1 56 ? 88.997 10.421 33.606 1.00 20.38 ? 58 THR A C 1 ATOM 432 O O . THR A 1 56 ? 87.967 9.829 33.929 1.00 19.57 ? 58 THR A O 1 ATOM 433 C CB . THR A 1 56 ? 87.814 12.537 34.210 1.00 20.48 ? 58 THR A CB 1 ATOM 434 O OG1 . THR A 1 56 ? 87.078 12.595 32.981 1.00 20.68 ? 58 THR A OG1 1 ATOM 435 C CG2 . THR A 1 56 ? 87.964 13.944 34.778 1.00 19.94 ? 58 THR A CG2 1 ATOM 436 N N . GLN A 1 57 ? 89.992 9.828 32.955 1.00 21.51 ? 59 GLN A N 1 ATOM 437 C CA . GLN A 1 57 ? 89.976 8.394 32.689 1.00 21.98 ? 59 GLN A CA 1 ATOM 438 C C . GLN A 1 57 ? 90.189 7.622 33.982 1.00 19.62 ? 59 GLN A C 1 ATOM 439 O O . GLN A 1 57 ? 91.185 7.827 34.669 1.00 21.70 ? 59 GLN A O 1 ATOM 440 C CB . GLN A 1 57 ? 91.065 8.027 31.677 1.00 24.22 ? 59 GLN A CB 1 ATOM 441 C CG . GLN A 1 57 ? 90.938 8.746 30.344 1.00 24.84 ? 59 GLN A CG 1 ATOM 442 C CD . GLN A 1 57 ? 89.621 8.450 29.654 1.00 26.13 ? 59 GLN A CD 1 ATOM 443 O OE1 . GLN A 1 57 ? 88.817 9.351 29.408 1.00 25.11 ? 59 GLN A OE1 1 ATOM 444 N NE2 . GLN A 1 57 ? 89.386 7.179 29.352 1.00 27.73 ? 59 GLN A NE2 1 ATOM 445 N N . PRO A 1 58 ? 89.255 6.721 34.318 1.00 19.00 ? 60 PRO A N 1 ATOM 446 C CA . PRO A 1 58 ? 89.453 5.857 35.477 1.00 17.97 ? 60 PRO A CA 1 ATOM 447 C C . PRO A 1 58 ? 90.567 4.844 35.228 1.00 16.94 ? 60 PRO A C 1 ATOM 448 O O . PRO A 1 58 ? 90.806 4.455 34.087 1.00 15.58 ? 60 PRO A O 1 ATOM 449 C CB . PRO A 1 58 ? 88.109 5.137 35.606 1.00 17.70 ? 60 PRO A CB 1 ATOM 450 C CG . PRO A 1 58 ? 87.566 5.110 34.218 1.00 17.59 ? 60 PRO A CG 1 ATOM 451 C CD . PRO A 1 58 ? 88.036 6.379 33.564 1.00 18.87 ? 60 PRO A CD 1 ATOM 452 N N . LEU A 1 59 ? 91.231 4.420 36.297 1.00 16.23 ? 61 LEU A N 1 ATOM 453 C CA . LEU A 1 59 ? 92.241 3.372 36.215 1.00 16.73 ? 61 LEU A CA 1 ATOM 454 C C . LEU A 1 59 ? 91.630 2.100 35.633 1.00 15.32 ? 61 LEU A C 1 ATOM 455 O O . LEU A 1 59 ? 92.188 1.481 34.725 1.00 15.39 ? 61 LEU A O 1 ATOM 456 C CB . LEU A 1 59 ? 92.812 3.094 37.607 1.00 17.04 ? 61 LEU A CB 1 ATOM 457 C CG . LEU A 1 59 ? 94.069 2.227 37.714 1.00 18.51 ? 61 LEU A CG 1 ATOM 458 C CD1 . LEU A 1 59 ? 95.155 2.722 36.772 1.00 18.81 ? 61 LEU A CD1 1 ATOM 459 C CD2 . LEU A 1 59 ? 94.572 2.221 39.150 1.00 19.15 ? 61 LEU A CD2 1 ATOM 460 N N . VAL A 1 60 ? 90.471 1.724 36.158 1.00 14.63 ? 62 VAL A N 1 ATOM 461 C CA . VAL A 1 60 ? 89.670 0.659 35.568 1.00 14.10 ? 62 VAL A CA 1 ATOM 462 C C . VAL A 1 60 ? 88.271 1.183 35.259 1.00 13.55 ? 62 VAL A C 1 ATOM 463 O O . VAL A 1 60 ? 87.575 1.669 36.148 1.00 13.11 ? 62 VAL A O 1 ATOM 464 C CB . VAL A 1 60 ? 89.567 -0.554 36.512 1.00 13.87 ? 62 VAL A CB 1 ATOM 465 C CG1 . VAL A 1 60 ? 88.706 -1.644 35.887 1.00 13.77 ? 62 VAL A CG1 1 ATOM 466 C CG2 . VAL A 1 60 ? 90.956 -1.089 36.832 1.00 14.12 ? 62 VAL A CG2 1 ATOM 467 N N . ALA A 1 61 ? 87.898 1.156 33.984 1.00 12.48 ? 63 ALA A N 1 ATOM 468 C CA . ALA A 1 61 ? 86.545 1.509 33.577 1.00 12.11 ? 63 ALA A CA 1 ATOM 469 C C . ALA A 1 61 ? 85.613 0.323 33.801 1.00 12.36 ? 63 ALA A C 1 ATOM 470 O O . ALA A 1 61 ? 85.916 -0.801 33.393 1.00 12.99 ? 63 ALA A O 1 ATOM 471 C CB . ALA A 1 61 ? 86.520 1.941 32.116 1.00 11.55 ? 63 ALA A CB 1 ATOM 472 N N . LEU A 1 62 ? 84.516 0.560 34.511 1.00 11.12 ? 64 LEU A N 1 ATOM 473 C CA . LEU A 1 62 ? 83.554 -0.501 34.791 1.00 11.38 ? 64 LEU A CA 1 ATOM 474 C C . LEU A 1 62 ? 82.166 -0.163 34.257 1.00 10.78 ? 64 LEU A C 1 ATOM 475 O O . LEU A 1 62 ? 81.646 0.926 34.495 1.00 10.75 ? 64 LEU A O 1 ATOM 476 C CB . LEU A 1 62 ? 83.493 -0.796 36.293 1.00 11.39 ? 64 LEU A CB 1 ATOM 477 C CG . LEU A 1 62 ? 82.589 -1.948 36.746 1.00 12.84 ? 64 LEU A CG 1 ATOM 478 C CD1 . LEU A 1 62 ? 83.048 -2.496 38.092 1.00 15.08 ? 64 LEU A CD1 1 ATOM 479 C CD2 . LEU A 1 62 ? 81.138 -1.494 36.825 1.00 12.21 ? 64 LEU A CD2 1 ATOM 480 N N . ASN A 1 63 ? 81.577 -1.103 33.526 1.00 10.76 ? 65 ASN A N 1 ATOM 481 C CA . ASN A 1 63 ? 80.171 -1.025 33.150 1.00 10.21 ? 65 ASN A CA 1 ATOM 482 C C . ASN A 1 63 ? 79.473 -2.301 33.605 1.00 10.01 ? 65 ASN A C 1 ATOM 483 O O . ASN A 1 63 ? 80.129 -3.318 33.838 1.00 10.00 ? 65 ASN A O 1 ATOM 484 C CB . ASN A 1 63 ? 80.035 -0.879 31.631 1.00 10.27 ? 65 ASN A CB 1 ATOM 485 C CG . ASN A 1 63 ? 80.036 0.570 31.168 1.00 10.81 ? 65 ASN A CG 1 ATOM 486 O OD1 . ASN A 1 63 ? 79.624 0.865 30.046 1.00 10.44 ? 65 ASN A OD1 1 ATOM 487 N ND2 . ASN A 1 63 ? 80.522 1.477 32.016 1.00 10.51 ? 65 ASN A ND2 1 ATOM 488 N N . ILE A 1 64 ? 78.152 -2.251 33.747 1.00 9.89 ? 66 ILE A N 1 ATOM 489 C CA . ILE A 1 64 ? 77.401 -3.425 34.197 1.00 9.78 ? 66 ILE A CA 1 ATOM 490 C C . ILE A 1 64 ? 76.036 -3.537 33.522 1.00 9.91 ? 66 ILE A C 1 ATOM 491 O O . ILE A 1 64 ? 75.353 -2.538 33.305 1.00 10.43 ? 66 ILE A O 1 ATOM 492 C CB . ILE A 1 64 ? 77.239 -3.443 35.732 1.00 10.09 ? 66 ILE A CB 1 ATOM 493 C CG1 . ILE A 1 64 ? 76.596 -4.755 36.188 1.00 10.23 ? 66 ILE A CG1 1 ATOM 494 C CG2 . ILE A 1 64 ? 76.427 -2.243 36.201 1.00 10.20 ? 66 ILE A CG2 1 ATOM 495 C CD1 . ILE A 1 64 ? 76.835 -5.075 37.647 1.00 10.66 ? 66 ILE A CD1 1 ATOM 496 N N . ALA A 1 65 ? 75.661 -4.756 33.155 1.00 9.56 ? 67 ALA A N 1 ATOM 497 C CA . ALA A 1 65 ? 74.406 -4.987 32.454 1.00 9.67 ? 67 ALA A CA 1 ATOM 498 C C . ALA A 1 65 ? 73.752 -6.271 32.946 1.00 9.73 ? 67 ALA A C 1 ATOM 499 O O . ALA A 1 65 ? 74.438 -7.200 33.382 1.00 9.58 ? 67 ALA A O 1 ATOM 500 C CB . ALA A 1 65 ? 74.638 -5.041 30.948 1.00 9.30 ? 67 ALA A CB 1 ATOM 501 N N . PHE A 1 66 ? 72.423 -6.304 32.906 1.00 9.59 ? 68 PHE A N 1 ATOM 502 C CA . PHE A 1 66 ? 71.660 -7.404 33.480 1.00 9.80 ? 68 PHE A CA 1 ATOM 503 C C . PHE A 1 66 ? 70.807 -8.105 32.428 1.00 9.99 ? 68 PHE A C 1 ATOM 504 O O . PHE A 1 66 ? 70.227 -7.459 31.555 1.00 9.21 ? 68 PHE A O 1 ATOM 505 C CB . PHE A 1 66 ? 70.780 -6.897 34.630 1.00 10.16 ? 68 PHE A CB 1 ATOM 506 C CG . PHE A 1 66 ? 71.563 -6.362 35.797 1.00 10.15 ? 68 PHE A CG 1 ATOM 507 C CD1 . PHE A 1 66 ? 71.990 -7.208 36.805 1.00 10.54 ? 68 PHE A CD1 1 ATOM 508 C CD2 . PHE A 1 66 ? 71.928 -5.025 35.851 1.00 10.65 ? 68 PHE A CD2 1 ATOM 509 C CE1 . PHE A 1 66 ? 72.744 -6.732 37.859 1.00 10.30 ? 68 PHE A CE1 1 ATOM 510 C CE2 . PHE A 1 66 ? 72.688 -4.542 36.900 1.00 10.53 ? 68 PHE A CE2 1 ATOM 511 C CZ . PHE A 1 66 ? 73.093 -5.396 37.908 1.00 10.45 ? 68 PHE A CZ 1 ATOM 512 N N . SER A 1 67 ? 70.760 -9.434 32.497 1.00 10.01 ? 69 SER A N 1 ATOM 513 C CA . SER A 1 67 ? 69.861 -10.206 31.648 1.00 9.96 ? 69 SER A CA 1 ATOM 514 C C . SER A 1 67 ? 68.447 -10.081 32.191 1.00 10.26 ? 69 SER A C 1 ATOM 515 O O . SER A 1 67 ? 68.246 -9.576 33.295 1.00 9.87 ? 69 SER A O 1 ATOM 516 C CB . SER A 1 67 ? 70.266 -11.679 31.653 1.00 10.40 ? 69 SER A CB 1 ATOM 517 O OG . SER A 1 67 ? 69.959 -12.271 32.907 1.00 10.95 ? 69 SER A OG 1 ATOM 518 N N . ASN A 1 68 ? 67.480 -10.618 31.456 1.00 10.68 ? 70 ASN A N 1 ATOM 519 C CA . ASN A 1 68 ? 66.111 -10.686 31.956 1.00 11.34 ? 70 ASN A CA 1 ATOM 520 C C . ASN A 1 68 ? 66.020 -11.464 33.266 1.00 11.44 ? 70 ASN A C 1 ATOM 521 O O . ASN A 1 68 ? 65.364 -11.028 34.211 1.00 10.70 ? 70 ASN A O 1 ATOM 522 C CB . ASN A 1 68 ? 65.178 -11.301 30.915 1.00 11.40 ? 70 ASN A CB 1 ATOM 523 C CG . ASN A 1 68 ? 63.783 -11.539 31.457 1.00 12.01 ? 70 ASN A CG 1 ATOM 524 O OD1 . ASN A 1 68 ? 63.042 -10.594 31.721 1.00 12.59 ? 70 ASN A OD1 1 ATOM 525 N ND2 . ASN A 1 68 ? 63.436 -12.806 31.673 1.00 11.76 ? 70 ASN A ND2 1 ATOM 526 N N . THR A 1 69 ? 66.695 -12.608 33.329 1.00 11.74 ? 71 THR A N 1 ATOM 527 C CA . THR A 1 69 ? 66.647 -13.433 34.533 1.00 11.69 ? 71 THR A CA 1 ATOM 528 C C . THR A 1 69 ? 67.371 -12.779 35.705 1.00 11.72 ? 71 THR A C 1 ATOM 529 O O . THR A 1 69 ? 66.978 -12.950 36.860 1.00 11.97 ? 71 THR A O 1 ATOM 530 C CB . THR A 1 69 ? 67.200 -14.850 34.292 1.00 12.45 ? 71 THR A CB 1 ATOM 531 O OG1 . THR A 1 69 ? 68.435 -14.770 33.574 1.00 13.69 ? 71 THR A OG1 1 ATOM 532 C CG2 . THR A 1 69 ? 66.204 -15.680 33.493 1.00 11.83 ? 71 THR A CG2 1 ATOM 533 N N . GLY A 1 70 ? 68.407 -12.003 35.400 1.00 10.84 ? 72 GLY A N 1 ATOM 534 C CA . GLY A 1 70 ? 69.087 -11.197 36.402 1.00 10.63 ? 72 GLY A CA 1 ATOM 535 C C . GLY A 1 70 ? 68.183 -10.146 37.017 1.00 11.07 ? 72 GLY A C 1 ATOM 536 O O . GLY A 1 70 ? 68.182 -9.954 38.232 1.00 11.01 ? 72 GLY A O 1 ATOM 537 N N . LEU A 1 71 ? 67.410 -9.462 36.178 1.00 11.22 ? 73 LEU A N 1 ATOM 538 C CA . LEU A 1 71 ? 66.438 -8.489 36.672 1.00 11.94 ? 73 LEU A CA 1 ATOM 539 C C . LEU A 1 71 ? 65.389 -9.167 37.544 1.00 12.74 ? 73 LEU A C 1 ATOM 540 O O . LEU A 1 71 ? 65.056 -8.680 38.632 1.00 13.65 ? 73 LEU A O 1 ATOM 541 C CB . LEU A 1 71 ? 65.772 -7.745 35.511 1.00 11.95 ? 73 LEU A CB 1 ATOM 542 C CG . LEU A 1 71 ? 66.677 -6.765 34.757 1.00 11.99 ? 73 LEU A CG 1 ATOM 543 C CD1 . LEU A 1 71 ? 65.943 -6.134 33.583 1.00 11.45 ? 73 LEU A CD1 1 ATOM 544 C CD2 . LEU A 1 71 ? 67.220 -5.693 35.693 1.00 11.93 ? 73 LEU A CD2 1 ATOM 545 N N . LEU A 1 72 ? 64.913 -10.324 37.097 1.00 12.77 ? 74 LEU A N 1 ATOM 546 C CA . LEU A 1 72 ? 63.967 -11.099 37.889 1.00 13.97 ? 74 LEU A CA 1 ATOM 547 C C . LEU A 1 72 ? 64.552 -11.492 39.245 1.00 14.70 ? 74 LEU A C 1 ATOM 548 O O . LEU A 1 72 ? 63.860 -11.452 40.260 1.00 14.32 ? 74 LEU A O 1 ATOM 549 C CB . LEU A 1 72 ? 63.503 -12.337 37.123 1.00 13.99 ? 74 LEU A CB 1 ATOM 550 C CG . LEU A 1 72 ? 62.595 -12.060 35.922 1.00 13.76 ? 74 LEU A CG 1 ATOM 551 C CD1 . LEU A 1 72 ? 62.154 -13.361 35.269 1.00 14.28 ? 74 LEU A CD1 1 ATOM 552 C CD2 . LEU A 1 72 ? 61.388 -11.241 36.349 1.00 14.12 ? 74 LEU A CD2 1 ATOM 553 N N . ALA A 1 73 ? 65.834 -11.845 39.264 1.00 14.67 ? 75 ALA A N 1 ATOM 554 C CA . ALA A 1 73 ? 66.482 -12.264 40.503 1.00 14.67 ? 75 ALA A CA 1 ATOM 555 C C . ALA A 1 73 ? 66.559 -11.106 41.493 1.00 14.74 ? 75 ALA A C 1 ATOM 556 O O . ALA A 1 73 ? 66.573 -11.313 42.708 1.00 14.82 ? 75 ALA A O 1 ATOM 557 C CB . ALA A 1 73 ? 67.870 -12.822 40.218 1.00 14.12 ? 75 ALA A CB 1 ATOM 558 N N . LEU A 1 74 ? 66.615 -9.887 40.964 1.00 14.99 ? 76 LEU A N 1 ATOM 559 C CA . LEU A 1 74 ? 66.672 -8.685 41.789 1.00 15.08 ? 76 LEU A CA 1 ATOM 560 C C . LEU A 1 74 ? 65.274 -8.189 42.162 1.00 15.61 ? 76 LEU A C 1 ATOM 561 O O . LEU A 1 74 ? 65.124 -7.116 42.749 1.00 16.97 ? 76 LEU A O 1 ATOM 562 C CB . LEU A 1 74 ? 67.439 -7.573 41.066 1.00 14.49 ? 76 LEU A CB 1 ATOM 563 C CG . LEU A 1 74 ? 68.950 -7.737 40.896 1.00 15.06 ? 76 LEU A CG 1 ATOM 564 C CD1 . LEU A 1 74 ? 69.506 -6.642 39.997 1.00 15.47 ? 76 LEU A CD1 1 ATOM 565 C CD2 . LEU A 1 74 ? 69.658 -7.739 42.242 1.00 14.85 ? 76 LEU A CD2 1 ATOM 566 N N . GLY A 1 75 ? 64.255 -8.962 41.808 1.00 14.94 ? 77 GLY A N 1 ATOM 567 C CA . GLY A 1 75 ? 62.875 -8.594 42.121 1.00 16.10 ? 77 GLY A CA 1 ATOM 568 C C . GLY A 1 75 ? 62.314 -7.520 41.207 1.00 16.83 ? 77 GLY A C 1 ATOM 569 O O . GLY A 1 75 ? 61.262 -6.944 41.486 1.00 17.04 ? 77 GLY A O 1 ATOM 570 N N . VAL A 1 76 ? 63.008 -7.252 40.106 1.00 15.15 ? 78 VAL A N 1 ATOM 571 C CA . VAL A 1 76 ? 62.543 -6.260 39.144 1.00 15.13 ? 78 VAL A CA 1 ATOM 572 C C . VAL A 1 76 ? 61.737 -6.925 38.034 1.00 15.95 ? 78 VAL A C 1 ATOM 573 O O . VAL A 1 76 ? 62.298 -7.562 37.141 1.00 15.66 ? 78 VAL A O 1 ATOM 574 C CB . VAL A 1 76 ? 63.711 -5.459 38.535 1.00 15.38 ? 78 VAL A CB 1 ATOM 575 C CG1 . VAL A 1 76 ? 63.188 -4.445 37.528 1.00 15.29 ? 78 VAL A CG1 1 ATOM 576 C CG2 . VAL A 1 76 ? 64.512 -4.765 39.633 1.00 14.43 ? 78 VAL A CG2 1 ATOM 577 N N . THR A 1 77 ? 60.416 -6.799 38.117 1.00 15.48 ? 79 THR A N 1 ATOM 578 C CA . THR A 1 77 ? 59.512 -7.585 37.284 1.00 16.28 ? 79 THR A CA 1 ATOM 579 C C . THR A 1 77 ? 58.876 -6.726 36.194 1.00 16.37 ? 79 THR A C 1 ATOM 580 O O . THR A 1 77 ? 58.037 -7.203 35.427 1.00 15.96 ? 79 THR A O 1 ATOM 581 C CB . THR A 1 77 ? 58.395 -8.225 38.126 1.00 17.28 ? 79 THR A CB 1 ATOM 582 O OG1 . THR A 1 77 ? 57.717 -7.204 38.866 1.00 16.82 ? 79 THR A OG1 1 ATOM 583 C CG2 . THR A 1 77 ? 58.975 -9.247 39.101 1.00 17.31 ? 79 THR A CG2 1 ATOM 584 N N . ASP A 1 78 ? 59.299 -5.466 36.121 1.00 14.37 ? 80 ASP A N 1 ATOM 585 C CA . ASP A 1 78 ? 58.778 -4.520 35.138 1.00 14.86 ? 80 ASP A CA 1 ATOM 586 C C . ASP A 1 78 ? 58.984 -5.010 33.706 1.00 14.48 ? 80 ASP A C 1 ATOM 587 O O . ASP A 1 78 ? 59.974 -5.679 33.400 1.00 14.53 ? 80 ASP A O 1 ATOM 588 C CB . ASP A 1 78 ? 59.448 -3.151 35.299 1.00 14.75 ? 80 ASP A CB 1 ATOM 589 C CG . ASP A 1 78 ? 59.348 -2.608 36.713 1.00 15.48 ? 80 ASP A CG 1 ATOM 590 O OD1 . ASP A 1 78 ? 58.520 -3.120 37.498 1.00 19.10 ? 80 ASP A OD1 1 ATOM 591 O OD2 . ASP A 1 78 ? 60.084 -1.651 37.036 1.00 15.18 ? 80 ASP A OD2 1 ATOM 592 N N . ASN A 1 79 ? 58.067 -4.625 32.826 1.00 14.10 ? 81 ASN A N 1 ATOM 593 C CA . ASN A 1 79 ? 58.203 -4.866 31.393 1.00 14.14 ? 81 ASN A CA 1 ATOM 594 C C . ASN A 1 79 ? 59.137 -3.839 30.746 1.00 14.45 ? 81 ASN A C 1 ATOM 595 O O . ASN A 1 79 ? 58.815 -2.654 30.681 1.00 14.30 ? 81 ASN A O 1 ATOM 596 C CB . ASN A 1 79 ? 56.822 -4.809 30.735 1.00 13.98 ? 81 ASN A CB 1 ATOM 597 C CG . ASN A 1 79 ? 56.849 -5.199 29.271 1.00 14.27 ? 81 ASN A CG 1 ATOM 598 O OD1 . ASN A 1 79 ? 57.910 -5.407 28.686 1.00 15.15 ? 81 ASN A OD1 1 ATOM 599 N ND2 . ASN A 1 79 ? 55.670 -5.295 28.668 1.00 14.30 ? 81 ASN A ND2 1 ATOM 600 N N . LEU A 1 80 ? 60.292 -4.302 30.271 1.00 14.03 ? 82 LEU A N 1 ATOM 601 C CA . LEU A 1 80 ? 61.271 -3.425 29.628 1.00 13.59 ? 82 LEU A CA 1 ATOM 602 C C . LEU A 1 80 ? 60.886 -3.111 28.187 1.00 13.02 ? 82 LEU A C 1 ATOM 603 O O . LEU A 1 80 ? 61.506 -2.267 27.545 1.00 13.71 ? 82 LEU A O 1 ATOM 604 C CB . LEU A 1 80 ? 62.667 -4.057 29.664 1.00 14.44 ? 82 LEU A CB 1 ATOM 605 C CG . LEU A 1 80 ? 63.538 -3.803 30.898 1.00 15.33 ? 82 LEU A CG 1 ATOM 606 C CD1 . LEU A 1 80 ? 64.047 -2.372 30.900 1.00 17.28 ? 82 LEU A CD1 1 ATOM 607 C CD2 . LEU A 1 80 ? 62.782 -4.110 32.183 1.00 15.15 ? 82 LEU A CD2 1 ATOM 608 N N . GLY A 1 81 ? 59.891 -3.826 27.670 1.00 12.22 ? 83 GLY A N 1 ATOM 609 C CA . GLY A 1 81 ? 59.319 -3.513 26.366 1.00 12.51 ? 83 GLY A CA 1 ATOM 610 C C . GLY A 1 81 ? 60.068 -4.152 25.213 1.00 12.57 ? 83 GLY A C 1 ATOM 611 O O . GLY A 1 81 ? 59.925 -3.737 24.062 1.00 13.51 ? 83 GLY A O 1 ATOM 612 N N . ASP A 1 82 ? 60.841 -5.189 25.514 1.00 12.37 ? 84 ASP A N 1 ATOM 613 C CA . ASP A 1 82 ? 61.616 -5.882 24.487 1.00 12.41 ? 84 ASP A CA 1 ATOM 614 C C . ASP A 1 82 ? 61.465 -7.394 24.632 1.00 12.12 ? 84 ASP A C 1 ATOM 615 O O . ASP A 1 82 ? 62.028 -7.998 25.544 1.00 11.90 ? 84 ASP A O 1 ATOM 616 C CB . ASP A 1 82 ? 63.091 -5.481 24.574 1.00 12.61 ? 84 ASP A CB 1 ATOM 617 C CG . ASP A 1 82 ? 63.870 -5.849 23.322 1.00 13.44 ? 84 ASP A CG 1 ATOM 618 O OD1 . ASP A 1 82 ? 64.052 -7.061 23.070 1.00 13.11 ? 84 ASP A OD1 1 ATOM 619 O OD2 . ASP A 1 82 ? 64.296 -4.925 22.592 1.00 13.00 ? 84 ASP A OD2 1 ATOM 620 N N A SER A 1 83 ? 60.665 -7.981 23.746 0.50 12.17 ? 85 SER A N 1 ATOM 621 N N B SER A 1 83 ? 60.718 -8.012 23.724 0.50 12.07 ? 85 SER A N 1 ATOM 622 C CA A SER A 1 83 ? 60.366 -9.409 23.782 0.50 12.28 ? 85 SER A CA 1 ATOM 623 C CA B SER A 1 83 ? 60.386 -9.427 23.866 0.50 11.91 ? 85 SER A CA 1 ATOM 624 C C A SER A 1 83 ? 61.642 -10.234 23.667 0.50 11.71 ? 85 SER A C 1 ATOM 625 C C B SER A 1 83 ? 61.557 -10.353 23.533 0.50 11.51 ? 85 SER A C 1 ATOM 626 O O A SER A 1 83 ? 61.870 -11.162 24.446 0.50 11.73 ? 85 SER A O 1 ATOM 627 O O B SER A 1 83 ? 61.640 -11.466 24.052 0.50 11.40 ? 85 SER A O 1 ATOM 628 C CB A SER A 1 83 ? 59.409 -9.773 22.643 0.50 13.40 ? 85 SER A CB 1 ATOM 629 C CB B SER A 1 83 ? 59.149 -9.784 23.042 0.50 12.61 ? 85 SER A CB 1 ATOM 630 O OG A SER A 1 83 ? 59.062 -11.146 22.684 0.50 14.42 ? 85 SER A OG 1 ATOM 631 O OG B SER A 1 83 ? 57.964 -9.459 23.750 0.50 12.89 ? 85 SER A OG 1 ATOM 632 N N . LEU A 1 84 ? 62.475 -9.882 22.694 1.00 11.25 ? 86 LEU A N 1 ATOM 633 C CA . LEU A 1 84 ? 63.722 -10.603 22.449 1.00 10.59 ? 86 LEU A CA 1 ATOM 634 C C . LEU A 1 84 ? 64.603 -10.628 23.696 1.00 10.43 ? 86 LEU A C 1 ATOM 635 O O . LEU A 1 84 ? 65.135 -11.673 24.071 1.00 10.20 ? 86 LEU A O 1 ATOM 636 C CB . LEU A 1 84 ? 64.483 -9.980 21.278 1.00 10.21 ? 86 LEU A CB 1 ATOM 637 C CG . LEU A 1 84 ? 63.841 -10.116 19.894 1.00 11.10 ? 86 LEU A CG 1 ATOM 638 C CD1 . LEU A 1 84 ? 64.673 -9.390 18.848 1.00 10.79 ? 86 LEU A CD1 1 ATOM 639 C CD2 . LEU A 1 84 ? 63.663 -11.580 19.518 1.00 10.84 ? 86 LEU A CD2 1 ATOM 640 N N . PHE A 1 85 ? 64.761 -9.473 24.335 1.00 10.37 ? 87 PHE A N 1 ATOM 641 C CA . PHE A 1 85 ? 65.479 -9.402 25.606 1.00 10.64 ? 87 PHE A CA 1 ATOM 642 C C . PHE A 1 85 ? 64.875 -10.350 26.636 1.00 10.88 ? 87 PHE A C 1 ATOM 643 O O . PHE A 1 85 ? 65.596 -11.056 27.340 1.00 11.36 ? 87 PHE A O 1 ATOM 644 C CB . PHE A 1 85 ? 65.490 -7.968 26.148 1.00 10.31 ? 87 PHE A CB 1 ATOM 645 C CG . PHE A 1 85 ? 65.983 -7.858 27.566 1.00 10.30 ? 87 PHE A CG 1 ATOM 646 C CD1 . PHE A 1 85 ? 67.313 -8.104 27.876 1.00 10.45 ? 87 PHE A CD1 1 ATOM 647 C CD2 . PHE A 1 85 ? 65.120 -7.490 28.586 1.00 10.18 ? 87 PHE A CD2 1 ATOM 648 C CE1 . PHE A 1 85 ? 67.770 -7.994 29.180 1.00 10.34 ? 87 PHE A CE1 1 ATOM 649 C CE2 . PHE A 1 85 ? 65.571 -7.380 29.890 1.00 10.16 ? 87 PHE A CE2 1 ATOM 650 C CZ . PHE A 1 85 ? 66.897 -7.632 30.188 1.00 9.96 ? 87 PHE A CZ 1 ATOM 651 N N . ALA A 1 86 ? 63.550 -10.374 26.713 1.00 10.85 ? 88 ALA A N 1 ATOM 652 C CA . ALA A 1 86 ? 62.869 -11.177 27.722 1.00 12.01 ? 88 ALA A CA 1 ATOM 653 C C . ALA A 1 86 ? 63.103 -12.668 27.492 1.00 12.26 ? 88 ALA A C 1 ATOM 654 O O . ALA A 1 86 ? 63.357 -13.417 28.434 1.00 12.86 ? 88 ALA A O 1 ATOM 655 C CB . ALA A 1 86 ? 61.380 -10.861 27.744 1.00 12.59 ? 88 ALA A CB 1 ATOM 656 N N . ASN A 1 87 ? 63.050 -13.088 26.232 1.00 13.51 ? 89 ASN A N 1 ATOM 657 C CA . ASN A 1 87 ? 63.219 -14.498 25.887 1.00 14.37 ? 89 ASN A CA 1 ATOM 658 C C . ASN A 1 87 ? 64.663 -14.991 25.996 1.00 13.46 ? 89 ASN A C 1 ATOM 659 O O . ASN A 1 87 ? 64.907 -16.182 26.191 1.00 12.74 ? 89 ASN A O 1 ATOM 660 C CB . ASN A 1 87 ? 62.669 -14.778 24.489 1.00 15.55 ? 89 ASN A CB 1 ATOM 661 C CG . ASN A 1 87 ? 61.159 -14.868 24.471 1.00 18.34 ? 89 ASN A CG 1 ATOM 662 O OD1 . ASN A 1 87 ? 60.549 -15.401 25.397 1.00 20.65 ? 89 ASN A OD1 1 ATOM 663 N ND2 . ASN A 1 87 ? 60.547 -14.352 23.414 1.00 19.27 ? 89 ASN A ND2 1 ATOM 664 N N . GLY A 1 88 ? 65.618 -14.074 25.860 1.00 12.72 ? 90 GLY A N 1 ATOM 665 C CA . GLY A 1 88 ? 67.032 -14.440 25.910 1.00 12.58 ? 90 GLY A CA 1 ATOM 666 C C . GLY A 1 88 ? 67.563 -14.876 24.558 1.00 12.16 ? 90 GLY A C 1 ATOM 667 O O . GLY A 1 88 ? 66.808 -15.346 23.711 1.00 12.64 ? 90 GLY A O 1 ATOM 668 N N . GLN A 1 89 ? 68.872 -14.745 24.359 1.00 12.08 ? 91 GLN A N 1 ATOM 669 C CA . GLN A 1 89 ? 69.459 -14.955 23.041 1.00 11.03 ? 91 GLN A CA 1 ATOM 670 C C . GLN A 1 89 ? 69.402 -16.412 22.593 1.00 11.53 ? 91 GLN A C 1 ATOM 671 O O . GLN A 1 89 ? 69.288 -16.692 21.401 1.00 11.07 ? 91 GLN A O 1 ATOM 672 C CB . GLN A 1 89 ? 70.901 -14.444 22.984 1.00 10.69 ? 91 GLN A CB 1 ATOM 673 C CG . GLN A 1 89 ? 71.428 -14.293 21.565 1.00 10.44 ? 91 GLN A CG 1 ATOM 674 C CD . GLN A 1 89 ? 72.889 -13.887 21.521 1.00 10.24 ? 91 GLN A CD 1 ATOM 675 O OE1 . GLN A 1 89 ? 73.753 -14.688 21.174 1.00 10.26 ? 91 GLN A OE1 1 ATOM 676 N NE2 . GLN A 1 89 ? 73.174 -12.650 21.909 1.00 10.58 ? 91 GLN A NE2 1 ATOM 677 N N . ALA A 1 90 ? 69.473 -17.336 23.546 1.00 12.15 ? 92 ALA A N 1 ATOM 678 C CA . ALA A 1 90 ? 69.431 -18.759 23.215 1.00 12.99 ? 92 ALA A CA 1 ATOM 679 C C . ALA A 1 90 ? 68.164 -19.120 22.441 1.00 13.39 ? 92 ALA A C 1 ATOM 680 O O . ALA A 1 90 ? 68.213 -19.877 21.475 1.00 14.02 ? 92 ALA A O 1 ATOM 681 C CB . ALA A 1 90 ? 69.567 -19.613 24.469 1.00 12.12 ? 92 ALA A CB 1 ATOM 682 N N . LYS A 1 91 ? 67.035 -18.545 22.840 1.00 14.46 ? 93 LYS A N 1 ATOM 683 C CA . LYS A 1 91 ? 65.776 -18.776 22.133 1.00 14.52 ? 93 LYS A CA 1 ATOM 684 C C . LYS A 1 91 ? 65.788 -18.149 20.737 1.00 15.05 ? 93 LYS A C 1 ATOM 685 O O . LYS A 1 91 ? 65.017 -18.538 19.860 1.00 15.16 ? 93 LYS A O 1 ATOM 686 C CB . LYS A 1 91 ? 64.599 -18.227 22.940 1.00 15.37 ? 93 LYS A CB 1 ATOM 687 C CG . LYS A 1 91 ? 64.153 -19.130 24.078 1.00 17.79 ? 93 LYS A CG 1 ATOM 688 C CD . LYS A 1 91 ? 62.642 -19.081 24.240 1.00 20.82 ? 93 LYS A CD 1 ATOM 689 C CE . LYS A 1 91 ? 62.226 -19.287 25.688 1.00 20.91 ? 93 LYS A CE 1 ATOM 690 N NZ . LYS A 1 91 ? 63.087 -20.286 26.378 1.00 20.33 ? 93 LYS A NZ 1 ATOM 691 N N . ASP A 1 92 ? 66.672 -17.179 20.536 1.00 13.93 ? 94 ASP A N 1 ATOM 692 C CA . ASP A 1 92 ? 66.718 -16.434 19.284 1.00 14.41 ? 94 ASP A CA 1 ATOM 693 C C . ASP A 1 92 ? 67.617 -17.102 18.238 1.00 14.26 ? 94 ASP A C 1 ATOM 694 O O . ASP A 1 92 ? 67.683 -16.651 17.097 1.00 15.19 ? 94 ASP A O 1 ATOM 695 C CB . ASP A 1 92 ? 67.187 -15.000 19.547 1.00 13.93 ? 94 ASP A CB 1 ATOM 696 C CG . ASP A 1 92 ? 66.627 -14.003 18.548 1.00 13.80 ? 94 ASP A CG 1 ATOM 697 O OD1 . ASP A 1 92 ? 65.617 -14.313 17.880 1.00 14.18 ? 94 ASP A OD1 1 ATOM 698 O OD2 . ASP A 1 92 ? 67.182 -12.890 18.454 1.00 13.10 ? 94 ASP A OD2 1 ATOM 699 N N . ALA A 1 93 ? 68.306 -18.174 18.621 1.00 14.39 ? 95 ALA A N 1 ATOM 700 C CA . ALA A 1 93 ? 69.323 -18.769 17.747 1.00 15.17 ? 95 ALA A CA 1 ATOM 701 C C . ALA A 1 93 ? 68.749 -19.243 16.413 1.00 15.76 ? 95 ALA A C 1 ATOM 702 O O . ALA A 1 93 ? 69.402 -19.135 15.373 1.00 15.72 ? 95 ALA A O 1 ATOM 703 C CB . ALA A 1 93 ? 70.053 -19.906 18.451 1.00 14.84 ? 95 ALA A CB 1 ATOM 704 N N A THR A 1 94 ? 67.536 -19.787 16.451 0.50 15.78 ? 96 THR A N 1 ATOM 705 N N B THR A 1 94 ? 67.528 -19.768 16.443 0.50 16.11 ? 96 THR A N 1 ATOM 706 C CA A THR A 1 94 ? 66.884 -20.278 15.242 0.50 15.96 ? 96 THR A CA 1 ATOM 707 C CA B THR A 1 94 ? 66.900 -20.284 15.231 0.50 16.32 ? 96 THR A CA 1 ATOM 708 C C A THR A 1 94 ? 66.698 -19.153 14.232 0.50 15.64 ? 96 THR A C 1 ATOM 709 C C B THR A 1 94 ? 66.611 -19.169 14.230 0.50 15.83 ? 96 THR A C 1 ATOM 710 O O A THR A 1 94 ? 66.808 -19.366 13.025 0.50 14.98 ? 96 THR A O 1 ATOM 711 O O B THR A 1 94 ? 66.581 -19.404 13.021 0.50 15.21 ? 96 THR A O 1 ATOM 712 C CB A THR A 1 94 ? 65.512 -20.902 15.551 0.50 16.75 ? 96 THR A CB 1 ATOM 713 C CB B THR A 1 94 ? 65.601 -21.049 15.543 0.50 17.37 ? 96 THR A CB 1 ATOM 714 O OG1 A THR A 1 94 ? 65.633 -21.805 16.657 0.50 16.94 ? 96 THR A OG1 1 ATOM 715 O OG1 B THR A 1 94 ? 64.745 -20.234 16.354 0.50 17.40 ? 96 THR A OG1 1 ATOM 716 C CG2 A THR A 1 94 ? 64.985 -21.654 14.339 0.50 16.37 ? 96 THR A CG2 1 ATOM 717 C CG2 B THR A 1 94 ? 65.911 -22.341 16.282 0.50 17.80 ? 96 THR A CG2 1 ATOM 718 N N . SER A 1 95 ? 66.421 -17.953 14.735 1.00 15.35 ? 97 SER A N 1 ATOM 719 C CA . SER A 1 95 ? 66.218 -16.787 13.876 1.00 15.07 ? 97 SER A CA 1 ATOM 720 C C . SER A 1 95 ? 67.448 -16.511 13.019 1.00 15.74 ? 97 SER A C 1 ATOM 721 O O . SER A 1 95 ? 67.345 -15.905 11.954 1.00 16.31 ? 97 SER A O 1 ATOM 722 C CB . SER A 1 95 ? 65.901 -15.545 14.712 1.00 15.30 ? 97 SER A CB 1 ATOM 723 O OG . SER A 1 95 ? 64.708 -15.714 15.450 1.00 16.20 ? 97 SER A OG 1 ATOM 724 N N . PHE A 1 96 ? 68.615 -16.901 13.524 1.00 14.43 ? 98 PHE A N 1 ATOM 725 C CA . PHE A 1 96 ? 69.875 -16.625 12.848 1.00 14.34 ? 98 PHE A CA 1 ATOM 726 C C . PHE A 1 96 ? 70.372 -17.862 12.116 1.00 14.74 ? 98 PHE A C 1 ATOM 727 O O . PHE A 1 96 ? 71.489 -17.884 11.603 1.00 14.44 ? 98 PHE A O 1 ATOM 728 C CB . PHE A 1 96 ? 70.929 -16.155 13.853 1.00 14.40 ? 98 PHE A CB 1 ATOM 729 C CG . PHE A 1 96 ? 70.483 -14.997 14.699 1.00 13.17 ? 98 PHE A CG 1 ATOM 730 C CD1 . PHE A 1 96 ? 69.698 -13.993 14.159 1.00 12.83 ? 98 PHE A CD1 1 ATOM 731 C CD2 . PHE A 1 96 ? 70.860 -14.906 16.026 1.00 13.14 ? 98 PHE A CD2 1 ATOM 732 C CE1 . PHE A 1 96 ? 69.291 -12.923 14.931 1.00 13.08 ? 98 PHE A CE1 1 ATOM 733 C CE2 . PHE A 1 96 ? 70.452 -13.841 16.807 1.00 12.88 ? 98 PHE A CE2 1 ATOM 734 C CZ . PHE A 1 96 ? 69.672 -12.846 16.256 1.00 13.54 ? 98 PHE A CZ 1 ATOM 735 N N . LYS A 1 97 ? 69.542 -18.900 12.097 1.00 14.41 ? 99 LYS A N 1 ATOM 736 C CA . LYS A 1 97 ? 69.886 -20.135 11.411 1.00 15.37 ? 99 LYS A CA 1 ATOM 737 C C . LYS A 1 97 ? 71.202 -20.696 11.929 1.00 14.62 ? 99 LYS A C 1 ATOM 738 O O . LYS A 1 97 ? 72.072 -21.086 11.153 1.00 13.55 ? 99 LYS A O 1 ATOM 739 C CB . LYS A 1 97 ? 69.975 -19.899 9.904 1.00 15.74 ? 99 LYS A CB 1 ATOM 740 C CG . LYS A 1 97 ? 68.661 -19.487 9.263 1.00 17.21 ? 99 LYS A CG 1 ATOM 741 C CD . LYS A 1 97 ? 68.773 -19.529 7.748 1.00 19.77 ? 99 LYS A CD 1 ATOM 742 C CE . LYS A 1 97 ? 67.569 -18.889 7.077 1.00 20.20 ? 99 LYS A CE 1 ATOM 743 N NZ . LYS A 1 97 ? 67.681 -18.975 5.595 1.00 21.81 ? 99 LYS A NZ 1 ATOM 744 N N . GLU A 1 98 ? 71.353 -20.718 13.248 1.00 14.78 ? 100 GLU A N 1 ATOM 745 C CA . GLU A 1 98 ? 72.524 -21.327 13.860 1.00 15.80 ? 100 GLU A CA 1 ATOM 746 C C . GLU A 1 98 ? 72.123 -22.352 14.911 1.00 16.54 ? 100 GLU A C 1 ATOM 747 O O . GLU A 1 98 ? 71.014 -22.311 15.444 1.00 16.74 ? 100 GLU A O 1 ATOM 748 C CB . GLU A 1 98 ? 73.451 -20.263 14.461 1.00 15.44 ? 100 GLU A CB 1 ATOM 749 C CG . GLU A 1 98 ? 72.957 -19.643 15.760 1.00 14.84 ? 100 GLU A CG 1 ATOM 750 C CD . GLU A 1 98 ? 73.811 -18.467 16.209 1.00 15.01 ? 100 GLU A CD 1 ATOM 751 O OE1 . GLU A 1 98 ? 74.048 -17.551 15.392 1.00 14.55 ? 100 GLU A OE1 1 ATOM 752 O OE2 . GLU A 1 98 ? 74.234 -18.446 17.386 1.00 14.62 ? 100 GLU A OE2 1 ATOM 753 N N . SER A 1 99 ? 73.021 -23.297 15.167 1.00 17.82 ? 101 SER A N 1 ATOM 754 C CA . SER A 1 99 ? 72.791 -24.331 16.163 1.00 18.97 ? 101 SER A CA 1 ATOM 755 C C . SER A 1 99 ? 73.496 -23.966 17.467 1.00 18.72 ? 101 SER A C 1 ATOM 756 O O . SER A 1 99 ? 74.589 -23.402 17.452 1.00 19.93 ? 101 SER A O 1 ATOM 757 C CB . SER A 1 99 ? 73.302 -25.677 15.641 1.00 20.95 ? 101 SER A CB 1 ATOM 758 O OG . SER A 1 99 ? 73.380 -26.634 16.681 1.00 22.72 ? 101 SER A OG 1 ATOM 759 N N . THR A 1 100 ? 72.866 -24.288 18.592 1.00 17.87 ? 102 THR A N 1 ATOM 760 C CA . THR A 1 100 ? 73.474 -24.062 19.899 1.00 17.26 ? 102 THR A CA 1 ATOM 761 C C . THR A 1 100 ? 74.474 -25.158 20.258 1.00 16.91 ? 102 THR A C 1 ATOM 762 O O . THR A 1 100 ? 75.039 -25.161 21.352 1.00 15.93 ? 102 THR A O 1 ATOM 763 C CB . THR A 1 100 ? 72.415 -23.973 21.012 1.00 18.43 ? 102 THR A CB 1 ATOM 764 O OG1 . THR A 1 100 ? 71.523 -25.090 20.915 1.00 17.58 ? 102 THR A OG1 1 ATOM 765 C CG2 . THR A 1 100 ? 71.622 -22.677 20.892 1.00 18.38 ? 102 THR A CG2 1 ATOM 766 N N . SER A 1 101 ? 74.694 -26.085 19.332 1.00 17.11 ? 103 SER A N 1 ATOM 767 C CA . SER A 1 101 ? 75.717 -27.102 19.519 1.00 16.62 ? 103 SER A CA 1 ATOM 768 C C . SER A 1 101 ? 77.111 -26.481 19.607 1.00 15.92 ? 103 SER A C 1 ATOM 769 O O . SER A 1 101 ? 77.980 -27.000 20.298 1.00 15.49 ? 103 SER A O 1 ATOM 770 C CB . SER A 1 101 ? 75.655 -28.153 18.406 1.00 17.42 ? 103 SER A CB 1 ATOM 771 O OG . SER A 1 101 ? 75.958 -27.587 17.143 1.00 18.88 ? 103 SER A OG 1 ATOM 772 N N . SER A 1 102 ? 77.308 -25.345 18.945 1.00 15.99 ? 104 SER A N 1 ATOM 773 C CA . SER A 1 102 ? 78.601 -24.661 18.989 1.00 15.70 ? 104 SER A CA 1 ATOM 774 C C . SER A 1 102 ? 78.712 -23.642 20.126 1.00 14.94 ? 104 SER A C 1 ATOM 775 O O . SER A 1 102 ? 79.762 -23.028 20.316 1.00 14.51 ? 104 SER A O 1 ATOM 776 C CB . SER A 1 102 ? 78.891 -23.980 17.652 1.00 16.36 ? 104 SER A CB 1 ATOM 777 O OG . SER A 1 102 ? 77.898 -23.013 17.355 1.00 18.58 ? 104 SER A OG 1 ATOM 778 N N . TRP A 1 103 ? 77.632 -23.470 20.882 1.00 13.62 ? 105 TRP A N 1 ATOM 779 C CA . TRP A 1 103 ? 77.559 -22.411 21.884 1.00 12.86 ? 105 TRP A CA 1 ATOM 780 C C . TRP A 1 103 ? 78.393 -22.735 23.124 1.00 13.15 ? 105 TRP A C 1 ATOM 781 O O . TRP A 1 103 ? 78.482 -23.893 23.536 1.00 12.82 ? 105 TRP A O 1 ATOM 782 C CB . TRP A 1 103 ? 76.103 -22.172 22.291 1.00 12.82 ? 105 TRP A CB 1 ATOM 783 C CG . TRP A 1 103 ? 75.361 -21.248 21.378 1.00 12.87 ? 105 TRP A CG 1 ATOM 784 C CD1 . TRP A 1 103 ? 75.410 -21.226 20.015 1.00 13.13 ? 105 TRP A CD1 1 ATOM 785 C CD2 . TRP A 1 103 ? 74.424 -20.235 21.763 1.00 12.19 ? 105 TRP A CD2 1 ATOM 786 N NE1 . TRP A 1 103 ? 74.581 -20.244 19.527 1.00 13.28 ? 105 TRP A NE1 1 ATOM 787 C CE2 . TRP A 1 103 ? 73.966 -19.620 20.580 1.00 12.61 ? 105 TRP A CE2 1 ATOM 788 C CE3 . TRP A 1 103 ? 73.949 -19.771 22.995 1.00 12.35 ? 105 TRP A CE3 1 ATOM 789 C CZ2 . TRP A 1 103 ? 73.056 -18.563 20.590 1.00 11.72 ? 105 TRP A CZ2 1 ATOM 790 C CZ3 . TRP A 1 103 ? 73.052 -18.710 23.006 1.00 11.91 ? 105 TRP A CZ3 1 ATOM 791 C CH2 . TRP A 1 103 ? 72.608 -18.125 21.809 1.00 12.26 ? 105 TRP A CH2 1 ATOM 792 N N . VAL A 1 104 ? 78.977 -21.707 23.735 1.00 12.01 ? 106 VAL A N 1 ATOM 793 C CA . VAL A 1 104 ? 79.432 -21.813 25.121 1.00 12.37 ? 106 VAL A CA 1 ATOM 794 C C . VAL A 1 104 ? 78.275 -22.326 25.978 1.00 12.52 ? 106 VAL A C 1 ATOM 795 O O . VAL A 1 104 ? 77.173 -21.782 25.925 1.00 12.22 ? 106 VAL A O 1 ATOM 796 C CB . VAL A 1 104 ? 79.909 -20.453 25.665 1.00 11.70 ? 106 VAL A CB 1 ATOM 797 C CG1 . VAL A 1 104 ? 80.297 -20.565 27.134 1.00 11.33 ? 106 VAL A CG1 1 ATOM 798 C CG2 . VAL A 1 104 ? 81.074 -19.926 24.839 1.00 11.42 ? 106 VAL A CG2 1 ATOM 799 N N . PRO A 1 105 ? 78.505 -23.410 26.735 1.00 12.82 ? 107 PRO A N 1 ATOM 800 C CA . PRO A 1 105 ? 77.395 -24.021 27.463 1.00 13.35 ? 107 PRO A CA 1 ATOM 801 C C . PRO A 1 105 ? 76.677 -23.017 28.361 1.00 12.62 ? 107 PRO A C 1 ATOM 802 O O . PRO A 1 105 ? 75.448 -23.015 28.427 1.00 12.06 ? 107 PRO A O 1 ATOM 803 C CB . PRO A 1 105 ? 78.083 -25.097 28.305 1.00 14.37 ? 107 PRO A CB 1 ATOM 804 C CG . PRO A 1 105 ? 79.281 -25.480 27.498 1.00 13.73 ? 107 PRO A CG 1 ATOM 805 C CD . PRO A 1 105 ? 79.728 -24.230 26.789 1.00 13.34 ? 107 PRO A CD 1 ATOM 806 N N . GLN A 1 106 ? 77.442 -22.150 29.014 1.00 13.20 ? 108 GLN A N 1 ATOM 807 C CA . GLN A 1 106 ? 76.877 -21.134 29.899 1.00 13.08 ? 108 GLN A CA 1 ATOM 808 C C . GLN A 1 106 ? 75.923 -20.172 29.184 1.00 12.50 ? 108 GLN A C 1 ATOM 809 O O . GLN A 1 106 ? 75.008 -19.631 29.804 1.00 12.67 ? 108 GLN A O 1 ATOM 810 C CB . GLN A 1 106 ? 77.990 -20.358 30.607 1.00 12.78 ? 108 GLN A CB 1 ATOM 811 C CG . GLN A 1 106 ? 78.792 -21.184 31.605 1.00 13.34 ? 108 GLN A CG 1 ATOM 812 C CD . GLN A 1 106 ? 80.049 -21.787 31.001 1.00 13.63 ? 108 GLN A CD 1 ATOM 813 O OE1 . GLN A 1 106 ? 80.013 -22.387 29.927 1.00 13.78 ? 108 GLN A OE1 1 ATOM 814 N NE2 . GLN A 1 106 ? 81.169 -21.633 31.695 1.00 13.97 ? 108 GLN A NE2 1 ATOM 815 N N . PHE A 1 107 ? 76.124 -19.971 27.883 1.00 12.04 ? 109 PHE A N 1 ATOM 816 C CA . PHE A 1 107 ? 75.243 -19.092 27.105 1.00 11.91 ? 109 PHE A CA 1 ATOM 817 C C . PHE A 1 107 ? 73.959 -19.801 26.690 1.00 12.47 ? 109 PHE A C 1 ATOM 818 O O . PHE A 1 107 ? 72.949 -19.154 26.403 1.00 12.67 ? 109 PHE A O 1 ATOM 819 C CB . PHE A 1 107 ? 75.942 -18.560 25.848 1.00 11.34 ? 109 PHE A CB 1 ATOM 820 C CG . PHE A 1 107 ? 76.961 -17.483 26.113 1.00 11.67 ? 109 PHE A CG 1 ATOM 821 C CD1 . PHE A 1 107 ? 76.746 -16.522 27.085 1.00 11.95 ? 109 PHE A CD1 1 ATOM 822 C CD2 . PHE A 1 107 ? 78.107 -17.397 25.337 1.00 11.57 ? 109 PHE A CD2 1 ATOM 823 C CE1 . PHE A 1 107 ? 77.681 -15.524 27.316 1.00 12.21 ? 109 PHE A CE1 1 ATOM 824 C CE2 . PHE A 1 107 ? 79.045 -16.402 25.559 1.00 11.22 ? 109 PHE A CE2 1 ATOM 825 C CZ . PHE A 1 107 ? 78.838 -15.472 26.561 1.00 11.85 ? 109 PHE A CZ 1 ATOM 826 N N . ALA A 1 108 ? 74.021 -21.122 26.570 1.00 13.39 ? 110 ALA A N 1 ATOM 827 C CA . ALA A 1 108 ? 72.896 -21.881 26.026 1.00 13.49 ? 110 ALA A CA 1 ATOM 828 C C . ALA A 1 108 ? 71.865 -22.166 27.114 1.00 15.54 ? 110 ALA A C 1 ATOM 829 O O . ALA A 1 108 ? 71.726 -23.299 27.580 1.00 15.48 ? 110 ALA A O 1 ATOM 830 C CB . ALA A 1 108 ? 73.379 -23.171 25.382 1.00 13.20 ? 110 ALA A CB 1 ATOM 831 N N . GLY A 1 109 ? 71.152 -21.120 27.516 1.00 15.75 ? 111 GLY A N 1 ATOM 832 C CA . GLY A 1 109 ? 70.337 -21.147 28.725 1.00 15.91 ? 111 GLY A CA 1 ATOM 833 C C . GLY A 1 109 ? 70.049 -19.734 29.190 1.00 15.77 ? 111 GLY A C 1 ATOM 834 O O . GLY A 1 109 ? 70.351 -18.771 28.483 1.00 15.96 ? 111 GLY A O 1 ATOM 835 N N . THR A 1 110 ? 69.503 -19.602 30.395 1.00 15.50 ? 112 THR A N 1 ATOM 836 C CA . THR A 1 110 ? 69.282 -18.286 30.988 1.00 15.30 ? 112 THR A CA 1 ATOM 837 C C . THR A 1 110 ? 69.801 -18.214 32.421 1.00 14.73 ? 112 THR A C 1 ATOM 838 O O . THR A 1 110 ? 69.294 -17.445 33.241 1.00 15.00 ? 112 THR A O 1 ATOM 839 C CB . THR A 1 110 ? 67.792 -17.899 30.960 1.00 16.02 ? 112 THR A CB 1 ATOM 840 O OG1 . THR A 1 110 ? 67.022 -18.896 31.644 1.00 16.22 ? 112 THR A OG1 1 ATOM 841 C CG2 . THR A 1 110 ? 67.301 -17.778 29.526 1.00 16.75 ? 112 THR A CG2 1 ATOM 842 N N . GLY A 1 111 ? 70.839 -18.993 32.707 1.00 14.33 ? 113 GLY A N 1 ATOM 843 C CA . GLY A 1 111 ? 71.469 -18.981 34.021 1.00 13.57 ? 113 GLY A CA 1 ATOM 844 C C . GLY A 1 111 ? 72.271 -17.720 34.293 1.00 12.92 ? 113 GLY A C 1 ATOM 845 O O . GLY A 1 111 ? 72.448 -17.323 35.446 1.00 12.24 ? 113 GLY A O 1 ATOM 846 N N . ILE A 1 112 ? 72.758 -17.082 33.233 1.00 12.15 ? 114 ILE A N 1 ATOM 847 C CA . ILE A 1 112 ? 73.514 -15.841 33.387 1.00 11.28 ? 114 ILE A CA 1 ATOM 848 C C . ILE A 1 112 ? 72.606 -14.661 33.724 1.00 11.24 ? 114 ILE A C 1 ATOM 849 O O . ILE A 1 112 ? 71.670 -14.347 32.986 1.00 11.61 ? 114 ILE A O 1 ATOM 850 C CB . ILE A 1 112 ? 74.341 -15.508 32.131 1.00 11.18 ? 114 ILE A CB 1 ATOM 851 C CG1 . ILE A 1 112 ? 75.460 -16.534 31.944 1.00 11.04 ? 114 ILE A CG1 1 ATOM 852 C CG2 . ILE A 1 112 ? 74.923 -14.105 32.239 1.00 10.38 ? 114 ILE A CG2 1 ATOM 853 C CD1 . ILE A 1 112 ? 76.128 -16.447 30.587 1.00 11.30 ? 114 ILE A CD1 1 ATOM 854 N N . HIS A 1 113 ? 72.920 -13.989 34.827 1.00 10.89 ? 115 HIS A N 1 ATOM 855 C CA . HIS A 1 113 ? 72.093 -12.905 35.336 1.00 11.02 ? 115 HIS A CA 1 ATOM 856 C C . HIS A 1 113 ? 72.604 -11.529 34.918 1.00 10.25 ? 115 HIS A C 1 ATOM 857 O O . HIS A 1 113 ? 71.864 -10.546 34.964 1.00 9.83 ? 115 HIS A O 1 ATOM 858 C CB . HIS A 1 113 ? 71.985 -12.987 36.859 1.00 11.11 ? 115 HIS A CB 1 ATOM 859 C CG . HIS A 1 113 ? 71.157 -14.137 37.340 1.00 11.67 ? 115 HIS A CG 1 ATOM 860 N ND1 . HIS A 1 113 ? 71.196 -14.592 38.640 1.00 12.32 ? 115 HIS A ND1 1 ATOM 861 C CD2 . HIS A 1 113 ? 70.284 -14.940 36.686 1.00 12.12 ? 115 HIS A CD2 1 ATOM 862 C CE1 . HIS A 1 113 ? 70.374 -15.619 38.770 1.00 12.23 ? 115 HIS A CE1 1 ATOM 863 N NE2 . HIS A 1 113 ? 69.813 -15.853 37.597 1.00 13.22 ? 115 HIS A NE2 1 ATOM 864 N N . GLY A 1 114 ? 73.863 -11.457 34.504 1.00 9.67 ? 116 GLY A N 1 ATOM 865 C CA . GLY A 1 114 ? 74.443 -10.176 34.119 1.00 9.16 ? 116 GLY A CA 1 ATOM 866 C C . GLY A 1 114 ? 75.866 -10.267 33.618 1.00 8.79 ? 116 GLY A C 1 ATOM 867 O O . GLY A 1 114 ? 76.476 -11.335 33.628 1.00 8.37 ? 116 GLY A O 1 ATOM 868 N N . VAL A 1 115 ? 76.396 -9.132 33.180 1.00 9.22 ? 117 VAL A N 1 ATOM 869 C CA . VAL A 1 115 ? 77.797 -9.042 32.810 1.00 9.21 ? 117 VAL A CA 1 ATOM 870 C C . VAL A 1 115 ? 78.413 -7.777 33.396 1.00 9.27 ? 117 VAL A C 1 ATOM 871 O O . VAL A 1 115 ? 77.802 -6.704 33.372 1.00 9.42 ? 117 VAL A O 1 ATOM 872 C CB . VAL A 1 115 ? 77.986 -9.078 31.278 1.00 9.23 ? 117 VAL A CB 1 ATOM 873 C CG1 . VAL A 1 115 ? 77.257 -7.918 30.616 1.00 9.27 ? 117 VAL A CG1 1 ATOM 874 C CG2 . VAL A 1 115 ? 79.465 -9.067 30.920 1.00 8.80 ? 117 VAL A CG2 1 ATOM 875 N N . ILE A 1 116 ? 79.573 -7.935 34.022 1.00 9.22 ? 118 ILE A N 1 ATOM 876 C CA . ILE A 1 116 ? 80.423 -6.802 34.339 1.00 9.65 ? 118 ILE A CA 1 ATOM 877 C C . ILE A 1 116 ? 81.483 -6.655 33.255 1.00 10.10 ? 118 ILE A C 1 ATOM 878 O O . ILE A 1 116 ? 82.189 -7.617 32.923 1.00 9.93 ? 118 ILE A O 1 ATOM 879 C CB . ILE A 1 116 ? 81.093 -6.951 35.720 1.00 10.01 ? 118 ILE A CB 1 ATOM 880 C CG1 . ILE A 1 116 ? 80.032 -7.137 36.808 1.00 9.87 ? 118 ILE A CG1 1 ATOM 881 C CG2 . ILE A 1 116 ? 81.946 -5.730 36.034 1.00 10.05 ? 118 ILE A CG2 1 ATOM 882 C CD1 . ILE A 1 116 ? 80.610 -7.356 38.192 1.00 10.58 ? 118 ILE A CD1 1 ATOM 883 N N . ILE A 1 117 ? 81.535 -5.472 32.653 1.00 10.47 ? 119 ILE A N 1 ATOM 884 C CA . ILE A 1 117 ? 82.601 -5.134 31.718 1.00 11.14 ? 119 ILE A CA 1 ATOM 885 C C . ILE A 1 117 ? 83.675 -4.355 32.468 1.00 11.95 ? 119 ILE A C 1 ATOM 886 O O . ILE A 1 117 ? 83.404 -3.284 33.016 1.00 12.01 ? 119 ILE A O 1 ATOM 887 C CB . ILE A 1 117 ? 82.077 -4.275 30.549 1.00 11.49 ? 119 ILE A CB 1 ATOM 888 C CG1 . ILE A 1 117 ? 80.951 -4.998 29.809 1.00 12.10 ? 119 ILE A CG1 1 ATOM 889 C CG2 . ILE A 1 117 ? 83.203 -3.932 29.585 1.00 11.93 ? 119 ILE A CG2 1 ATOM 890 C CD1 . ILE A 1 117 ? 80.315 -4.158 28.720 1.00 12.63 ? 119 ILE A CD1 1 ATOM 891 N N . LEU A 1 118 ? 84.849 -4.963 32.599 1.00 12.04 ? 120 LEU A N 1 ATOM 892 C CA . LEU A 1 118 ? 86.015 -4.287 33.160 1.00 12.48 ? 120 LEU A CA 1 ATOM 893 C C . LEU A 1 118 ? 86.992 -3.969 32.041 1.00 12.35 ? 120 LEU A C 1 ATOM 894 O O . LEU A 1 118 ? 87.271 -4.817 31.202 1.00 12.61 ? 120 LEU A O 1 ATOM 895 C CB . LEU A 1 118 ? 86.700 -5.169 34.207 1.00 12.15 ? 120 LEU A CB 1 ATOM 896 C CG . LEU A 1 118 ? 85.845 -5.589 35.403 1.00 13.50 ? 120 LEU A CG 1 ATOM 897 C CD1 . LEU A 1 118 ? 86.726 -6.132 36.519 1.00 14.29 ? 120 LEU A CD1 1 ATOM 898 C CD2 . LEU A 1 118 ? 85.036 -4.404 35.902 1.00 14.00 ? 120 LEU A CD2 1 ATOM 899 N N . ALA A 1 119 ? 87.492 -2.739 32.023 1.00 12.57 ? 121 ALA A N 1 ATOM 900 C CA . ALA A 1 119 ? 88.420 -2.309 30.988 1.00 11.92 ? 121 ALA A CA 1 ATOM 901 C C . ALA A 1 119 ? 89.581 -1.537 31.602 1.00 12.89 ? 121 ALA A C 1 ATOM 902 O O . ALA A 1 119 ? 89.378 -0.614 32.385 1.00 13.70 ? 121 ALA A O 1 ATOM 903 C CB . ALA A 1 119 ? 87.701 -1.453 29.961 1.00 12.52 ? 121 ALA A CB 1 ATOM 904 N N . SER A 1 120 ? 90.800 -1.936 31.260 1.00 12.93 ? 122 SER A N 1 ATOM 905 C CA . SER A 1 120 ? 91.990 -1.264 31.762 1.00 14.31 ? 122 SER A CA 1 ATOM 906 C C . SER A 1 120 ? 93.129 -1.461 30.776 1.00 15.28 ? 122 SER A C 1 ATOM 907 O O . SER A 1 120 ? 93.027 -2.262 29.849 1.00 14.88 ? 122 SER A O 1 ATOM 908 C CB . SER A 1 120 ? 92.380 -1.817 33.136 1.00 13.54 ? 122 SER A CB 1 ATOM 909 O OG . SER A 1 120 ? 93.300 -0.955 33.783 1.00 12.82 ? 122 SER A OG 1 ATOM 910 N N . ASP A 1 121 ? 94.207 -0.710 30.950 1.00 17.35 ? 123 ASP A N 1 ATOM 911 C CA . ASP A 1 121 ? 95.313 -0.808 30.013 1.00 18.75 ? 123 ASP A CA 1 ATOM 912 C C . ASP A 1 121 ? 96.232 -1.980 30.332 1.00 17.70 ? 123 ASP A C 1 ATOM 913 O O . ASP A 1 121 ? 97.088 -2.335 29.530 1.00 18.24 ? 123 ASP A O 1 ATOM 914 C CB . ASP A 1 121 ? 96.080 0.509 29.920 1.00 20.29 ? 123 ASP A CB 1 ATOM 915 C CG . ASP A 1 121 ? 95.344 1.546 29.089 1.00 21.98 ? 123 ASP A CG 1 ATOM 916 O OD1 . ASP A 1 121 ? 94.607 1.147 28.157 1.00 18.90 ? 123 ASP A OD1 1 ATOM 917 O OD2 . ASP A 1 121 ? 95.470 2.752 29.389 1.00 22.68 ? 123 ASP A OD2 1 ATOM 918 N N . THR A 1 122 ? 95.996 -2.626 31.470 1.00 18.27 ? 124 THR A N 1 ATOM 919 C CA . THR A 1 122 ? 96.677 -3.879 31.785 1.00 17.92 ? 124 THR A CA 1 ATOM 920 C C . THR A 1 122 ? 95.717 -4.917 32.360 1.00 17.87 ? 124 THR A C 1 ATOM 921 O O . THR A 1 122 ? 94.720 -4.572 32.996 1.00 18.55 ? 124 THR A O 1 ATOM 922 C CB . THR A 1 122 ? 97.835 -3.671 32.780 1.00 18.65 ? 124 THR A CB 1 ATOM 923 O OG1 . THR A 1 122 ? 97.313 -3.581 34.110 1.00 19.15 ? 124 THR A OG1 1 ATOM 924 C CG2 . THR A 1 122 ? 98.612 -2.404 32.451 1.00 19.54 ? 124 THR A CG2 1 ATOM 925 N N . THR A 1 123 ? 96.040 -6.192 32.170 1.00 17.03 ? 125 THR A N 1 ATOM 926 C CA . THR A 1 123 ? 95.219 -7.260 32.723 1.00 17.50 ? 125 THR A CA 1 ATOM 927 C C . THR A 1 123 ? 95.434 -7.424 34.226 1.00 17.03 ? 125 THR A C 1 ATOM 928 O O . THR A 1 123 ? 94.562 -7.930 34.926 1.00 15.88 ? 125 THR A O 1 ATOM 929 C CB . THR A 1 123 ? 95.450 -8.601 32.004 1.00 18.37 ? 125 THR A CB 1 ATOM 930 O OG1 . THR A 1 123 ? 96.815 -9.000 32.155 1.00 19.83 ? 125 THR A OG1 1 ATOM 931 C CG2 . THR A 1 123 ? 95.127 -8.475 30.522 1.00 18.15 ? 125 THR A CG2 1 ATOM 932 N N . ASP A 1 124 ? 96.580 -6.966 34.724 1.00 16.72 ? 126 ASP A N 1 ATOM 933 C CA . ASP A 1 124 ? 96.838 -6.973 36.165 1.00 17.69 ? 126 ASP A CA 1 ATOM 934 C C . ASP A 1 124 ? 95.836 -6.096 36.904 1.00 15.54 ? 126 ASP A C 1 ATOM 935 O O . ASP A 1 124 ? 95.329 -6.473 37.957 1.00 15.62 ? 126 ASP A O 1 ATOM 936 C CB . ASP A 1 124 ? 98.263 -6.500 36.472 1.00 19.35 ? 126 ASP A CB 1 ATOM 937 C CG . ASP A 1 124 ? 99.282 -7.620 36.395 1.00 21.21 ? 126 ASP A CG 1 ATOM 938 O OD1 . ASP A 1 124 ? 98.901 -8.756 36.043 1.00 23.12 ? 126 ASP A OD1 1 ATOM 939 O OD2 . ASP A 1 124 ? 100.466 -7.369 36.708 1.00 22.75 ? 126 ASP A OD2 1 ATOM 940 N N . LEU A 1 125 ? 95.572 -4.910 36.364 1.00 15.82 ? 127 LEU A N 1 ATOM 941 C CA . LEU A 1 125 ? 94.610 -4.000 36.978 1.00 15.00 ? 127 LEU A CA 1 ATOM 942 C C . LEU A 1 125 ? 93.197 -4.580 36.954 1.00 14.55 ? 127 LEU A C 1 ATOM 943 O O . LEU A 1 125 ? 92.469 -4.509 37.943 1.00 14.27 ? 127 LEU A O 1 ATOM 944 C CB . LEU A 1 125 ? 94.650 -2.627 36.304 1.00 14.90 ? 127 LEU A CB 1 ATOM 945 C CG . LEU A 1 125 ? 95.917 -1.809 36.572 1.00 14.99 ? 127 LEU A CG 1 ATOM 946 C CD1 . LEU A 1 125 ? 95.978 -0.579 35.678 1.00 15.50 ? 127 LEU A CD1 1 ATOM 947 C CD2 . LEU A 1 125 ? 96.013 -1.419 38.040 1.00 14.97 ? 127 LEU A CD2 1 ATOM 948 N N . ILE A 1 126 ? 92.834 -5.205 35.839 1.00 13.62 ? 128 ILE A N 1 ATOM 949 C CA . ILE A 1 126 ? 91.554 -5.898 35.741 1.00 13.05 ? 128 ILE A CA 1 ATOM 950 C C . ILE A 1 126 ? 91.441 -7.000 36.795 1.00 13.20 ? 128 ILE A C 1 ATOM 951 O O . ILE A 1 126 ? 90.454 -7.077 37.523 1.00 12.19 ? 128 ILE A O 1 ATOM 952 C CB . ILE A 1 126 ? 91.345 -6.501 34.336 1.00 12.43 ? 128 ILE A CB 1 ATOM 953 C CG1 . ILE A 1 126 ? 91.142 -5.381 33.312 1.00 12.34 ? 128 ILE A CG1 1 ATOM 954 C CG2 . ILE A 1 126 ? 90.163 -7.463 34.335 1.00 12.20 ? 128 ILE A CG2 1 ATOM 955 C CD1 . ILE A 1 126 ? 90.832 -5.867 31.913 1.00 12.38 ? 128 ILE A CD1 1 ATOM 956 N N . ASP A 1 127 ? 92.469 -7.836 36.887 1.00 13.50 ? 129 ASP A N 1 ATOM 957 C CA . ASP A 1 127 ? 92.430 -8.989 37.777 1.00 14.84 ? 129 ASP A CA 1 ATOM 958 C C . ASP A 1 127 ? 92.264 -8.575 39.236 1.00 13.62 ? 129 ASP A C 1 ATOM 959 O O . ASP A 1 127 ? 91.579 -9.248 40.003 1.00 13.28 ? 129 ASP A O 1 ATOM 960 C CB . ASP A 1 127 ? 93.681 -9.853 37.607 1.00 17.01 ? 129 ASP A CB 1 ATOM 961 C CG . ASP A 1 127 ? 93.645 -10.692 36.341 1.00 19.79 ? 129 ASP A CG 1 ATOM 962 O OD1 . ASP A 1 127 ? 92.549 -10.873 35.770 1.00 22.80 ? 129 ASP A OD1 1 ATOM 963 O OD2 . ASP A 1 127 ? 94.714 -11.183 35.924 1.00 23.38 ? 129 ASP A OD2 1 ATOM 964 N N . GLN A 1 128 ? 92.896 -7.473 39.623 1.00 12.92 ? 130 GLN A N 1 ATOM 965 C CA . GLN A 1 128 ? 92.810 -7.021 41.004 1.00 13.97 ? 130 GLN A CA 1 ATOM 966 C C . GLN A 1 128 ? 91.426 -6.451 41.293 1.00 13.71 ? 130 GLN A C 1 ATOM 967 O O . GLN A 1 128 ? 90.895 -6.607 42.391 1.00 12.63 ? 130 GLN A O 1 ATOM 968 C CB . GLN A 1 128 ? 93.889 -5.982 41.309 1.00 13.44 ? 130 GLN A CB 1 ATOM 969 C CG . GLN A 1 128 ? 94.084 -5.731 42.795 1.00 13.84 ? 130 GLN A CG 1 ATOM 970 C CD . GLN A 1 128 ? 94.495 -6.983 43.549 1.00 14.70 ? 130 GLN A CD 1 ATOM 971 O OE1 . GLN A 1 128 ? 95.391 -7.716 43.121 1.00 14.44 ? 130 GLN A OE1 1 ATOM 972 N NE2 . GLN A 1 128 ? 93.854 -7.225 44.689 1.00 13.87 ? 130 GLN A NE2 1 ATOM 973 N N . GLN A 1 129 ? 90.840 -5.814 40.285 1.00 13.17 ? 131 GLN A N 1 ATOM 974 C CA . GLN A 1 129 ? 89.486 -5.279 40.395 1.00 14.50 ? 131 GLN A CA 1 ATOM 975 C C . GLN A 1 129 ? 88.470 -6.409 40.544 1.00 13.43 ? 131 GLN A C 1 ATOM 976 O O . GLN A 1 129 ? 87.543 -6.316 41.346 1.00 13.80 ? 131 GLN A O 1 ATOM 977 C CB . GLN A 1 129 ? 89.159 -4.408 39.177 1.00 15.33 ? 131 GLN A CB 1 ATOM 978 C CG . GLN A 1 129 ? 87.804 -3.720 39.234 1.00 17.41 ? 131 GLN A CG 1 ATOM 979 C CD . GLN A 1 129 ? 87.674 -2.770 40.408 1.00 20.12 ? 131 GLN A CD 1 ATOM 980 O OE1 . GLN A 1 129 ? 86.867 -2.990 41.311 1.00 24.90 ? 131 GLN A OE1 1 ATOM 981 N NE2 . GLN A 1 129 ? 88.480 -1.714 40.409 1.00 21.41 ? 131 GLN A NE2 1 ATOM 982 N N . VAL A 1 130 ? 88.683 -7.501 39.814 1.00 13.48 ? 132 VAL A N 1 ATOM 983 C CA . VAL A 1 130 ? 87.868 -8.702 39.988 1.00 13.30 ? 132 VAL A CA 1 ATOM 984 C C . VAL A 1 130 ? 87.993 -9.257 41.405 1.00 13.51 ? 132 VAL A C 1 ATOM 985 O O . VAL A 1 130 ? 86.993 -9.562 42.043 1.00 13.01 ? 132 VAL A O 1 ATOM 986 C CB . VAL A 1 130 ? 88.241 -9.807 38.983 1.00 13.29 ? 132 VAL A CB 1 ATOM 987 C CG1 . VAL A 1 130 ? 87.474 -11.084 39.296 1.00 13.29 ? 132 VAL A CG1 1 ATOM 988 C CG2 . VAL A 1 130 ? 87.953 -9.349 37.561 1.00 13.54 ? 132 VAL A CG2 1 ATOM 989 N N . ALA A 1 131 ? 89.225 -9.404 41.885 1.00 13.04 ? 133 ALA A N 1 ATOM 990 C CA . ALA A 1 131 ? 89.457 -9.877 43.249 1.00 13.98 ? 133 ALA A CA 1 ATOM 991 C C . ALA A 1 131 ? 88.712 -9.015 44.266 1.00 14.37 ? 133 ALA A C 1 ATOM 992 O O . ALA A 1 131 ? 88.102 -9.530 45.200 1.00 15.49 ? 133 ALA A O 1 ATOM 993 C CB . ALA A 1 131 ? 90.949 -9.893 43.559 1.00 13.13 ? 133 ALA A CB 1 ATOM 994 N N . SER A 1 132 ? 88.779 -7.699 44.088 1.00 14.66 ? 134 SER A N 1 ATOM 995 C CA . SER A 1 132 ? 88.090 -6.773 44.980 1.00 16.50 ? 134 SER A CA 1 ATOM 996 C C . SER A 1 132 ? 86.577 -6.977 44.919 1.00 15.77 ? 134 SER A C 1 ATOM 997 O O . SER A 1 132 ? 85.906 -7.056 45.949 1.00 15.55 ? 134 SER A O 1 ATOM 998 C CB . SER A 1 132 ? 88.446 -5.327 44.629 1.00 18.08 ? 134 SER A CB 1 ATOM 999 O OG . SER A 1 132 ? 87.608 -4.419 45.321 1.00 22.33 ? 134 SER A OG 1 ATOM 1000 N N . ILE A 1 133 ? 86.048 -7.102 43.707 1.00 14.49 ? 135 ILE A N 1 ATOM 1001 C CA . ILE A 1 133 ? 84.617 -7.310 43.530 1.00 14.76 ? 135 ILE A CA 1 ATOM 1002 C C . ILE A 1 133 ? 84.153 -8.615 44.173 1.00 14.90 ? 135 ILE A C 1 ATOM 1003 O O . ILE A 1 133 ? 83.168 -8.633 44.909 1.00 16.24 ? 135 ILE A O 1 ATOM 1004 C CB . ILE A 1 133 ? 84.213 -7.270 42.044 1.00 15.04 ? 135 ILE A CB 1 ATOM 1005 C CG1 . ILE A 1 133 ? 84.206 -5.823 41.541 1.00 14.05 ? 135 ILE A CG1 1 ATOM 1006 C CG2 . ILE A 1 133 ? 82.854 -7.928 41.845 1.00 14.28 ? 135 ILE A CG2 1 ATOM 1007 C CD1 . ILE A 1 133 ? 84.306 -5.693 40.034 1.00 13.88 ? 135 ILE A CD1 1 ATOM 1008 N N . GLU A 1 134 ? 84.895 -9.694 43.939 1.00 14.52 ? 136 GLU A N 1 ATOM 1009 C CA . GLU A 1 134 ? 84.545 -10.992 44.511 1.00 14.33 ? 136 GLU A CA 1 ATOM 1010 C C . GLU A 1 134 ? 84.673 -10.983 46.033 1.00 14.56 ? 136 GLU A C 1 ATOM 1011 O O . GLU A 1 134 ? 83.910 -11.649 46.730 1.00 14.50 ? 136 GLU A O 1 ATOM 1012 C CB . GLU A 1 134 ? 85.401 -12.108 43.900 1.00 14.14 ? 136 GLU A CB 1 ATOM 1013 C CG . GLU A 1 134 ? 85.161 -12.317 42.410 1.00 14.55 ? 136 GLU A CG 1 ATOM 1014 C CD . GLU A 1 134 ? 85.879 -13.535 41.860 1.00 15.90 ? 136 GLU A CD 1 ATOM 1015 O OE1 . GLU A 1 134 ? 86.801 -14.042 42.534 1.00 15.99 ? 136 GLU A OE1 1 ATOM 1016 O OE2 . GLU A 1 134 ? 85.530 -13.980 40.745 1.00 17.47 ? 136 GLU A OE2 1 ATOM 1017 N N . SER A 1 135 ? 85.599 -10.177 46.542 1.00 14.78 ? 137 SER A N 1 ATOM 1018 C CA . SER A 1 135 ? 85.853 -10.119 47.978 1.00 16.71 ? 137 SER A CA 1 ATOM 1019 C C . SER A 1 135 ? 84.763 -9.345 48.716 1.00 17.40 ? 137 SER A C 1 ATOM 1020 O O . SER A 1 135 ? 84.386 -9.706 49.830 1.00 18.52 ? 137 SER A O 1 ATOM 1021 C CB . SER A 1 135 ? 87.230 -9.510 48.264 1.00 16.64 ? 137 SER A CB 1 ATOM 1022 O OG . SER A 1 135 ? 87.220 -8.100 48.099 1.00 18.00 ? 137 SER A OG 1 ATOM 1023 N N . THR A 1 136 ? 84.240 -8.298 48.086 1.00 17.51 ? 138 THR A N 1 ATOM 1024 C CA . THR A 1 136 ? 83.178 -7.507 48.704 1.00 19.54 ? 138 THR A CA 1 ATOM 1025 C C . THR A 1 136 ? 81.814 -8.178 48.572 1.00 17.59 ? 138 THR A C 1 ATOM 1026 O O . THR A 1 136 ? 81.033 -8.206 49.523 1.00 17.58 ? 138 THR A O 1 ATOM 1027 C CB . THR A 1 136 ? 83.113 -6.071 48.141 1.00 21.86 ? 138 THR A CB 1 ATOM 1028 O OG1 . THR A 1 136 ? 82.738 -6.110 46.760 1.00 25.17 ? 138 THR A OG1 1 ATOM 1029 C CG2 . THR A 1 136 ? 84.461 -5.378 48.277 1.00 20.53 ? 138 THR A CG2 1 ATOM 1030 N N . PHE A 1 137 ? 81.542 -8.746 47.401 1.00 16.38 ? 139 PHE A N 1 ATOM 1031 C CA . PHE A 1 137 ? 80.264 -9.406 47.151 1.00 15.57 ? 139 PHE A CA 1 ATOM 1032 C C . PHE A 1 137 ? 80.188 -10.761 47.839 1.00 16.63 ? 139 PHE A C 1 ATOM 1033 O O . PHE A 1 137 ? 79.109 -11.212 48.217 1.00 15.93 ? 139 PHE A O 1 ATOM 1034 C CB . PHE A 1 137 ? 80.023 -9.572 45.649 1.00 15.26 ? 139 PHE A CB 1 ATOM 1035 C CG . PHE A 1 137 ? 79.427 -8.359 44.993 1.00 15.10 ? 139 PHE A CG 1 ATOM 1036 C CD1 . PHE A 1 137 ? 80.236 -7.328 44.545 1.00 15.10 ? 139 PHE A CD1 1 ATOM 1037 C CD2 . PHE A 1 137 ? 78.055 -8.243 44.841 1.00 14.54 ? 139 PHE A CD2 1 ATOM 1038 C CE1 . PHE A 1 137 ? 79.689 -6.206 43.948 1.00 15.44 ? 139 PHE A CE1 1 ATOM 1039 C CE2 . PHE A 1 137 ? 77.502 -7.131 44.233 1.00 14.62 ? 139 PHE A CE2 1 ATOM 1040 C CZ . PHE A 1 137 ? 78.318 -6.106 43.797 1.00 14.45 ? 139 PHE A CZ 1 ATOM 1041 N N . GLY A 1 138 ? 81.335 -11.422 47.971 1.00 17.48 ? 140 GLY A N 1 ATOM 1042 C CA . GLY A 1 138 ? 81.386 -12.747 48.578 1.00 18.84 ? 140 GLY A CA 1 ATOM 1043 C C . GLY A 1 138 ? 80.517 -13.756 47.854 1.00 19.07 ? 140 GLY A C 1 ATOM 1044 O O . GLY A 1 138 ? 80.479 -13.794 46.624 1.00 19.34 ? 140 GLY A O 1 ATOM 1045 N N . SER A 1 139 ? 79.784 -14.554 48.622 1.00 19.60 ? 141 SER A N 1 ATOM 1046 C CA . SER A 1 139 ? 79.003 -15.650 48.062 1.00 19.15 ? 141 SER A CA 1 ATOM 1047 C C . SER A 1 139 ? 77.719 -15.182 47.379 1.00 18.44 ? 141 SER A C 1 ATOM 1048 O O . SER A 1 139 ? 76.981 -15.995 46.828 1.00 19.97 ? 141 SER A O 1 ATOM 1049 C CB . SER A 1 139 ? 78.659 -16.660 49.157 1.00 21.71 ? 141 SER A CB 1 ATOM 1050 O OG . SER A 1 139 ? 77.979 -16.020 50.224 1.00 23.88 ? 141 SER A OG 1 ATOM 1051 N N . SER A 1 140 ? 77.429 -13.885 47.444 1.00 16.83 ? 142 SER A N 1 ATOM 1052 C CA . SER A 1 140 ? 76.208 -13.359 46.829 1.00 17.36 ? 142 SER A CA 1 ATOM 1053 C C . SER A 1 140 ? 76.325 -13.312 45.308 1.00 17.78 ? 142 SER A C 1 ATOM 1054 O O . SER A 1 140 ? 75.330 -13.140 44.604 1.00 18.20 ? 142 SER A O 1 ATOM 1055 C CB . SER A 1 140 ? 75.864 -11.974 47.380 1.00 16.33 ? 142 SER A CB 1 ATOM 1056 O OG . SER A 1 140 ? 76.729 -10.980 46.854 1.00 17.59 ? 142 SER A OG 1 ATOM 1057 N N . ILE A 1 141 ? 77.546 -13.474 44.810 1.00 16.88 ? 143 ILE A N 1 ATOM 1058 C CA . ILE A 1 141 ? 77.799 -13.489 43.374 1.00 17.88 ? 143 ILE A CA 1 ATOM 1059 C C . ILE A 1 141 ? 78.526 -14.772 42.985 1.00 18.49 ? 143 ILE A C 1 ATOM 1060 O O . ILE A 1 141 ? 79.318 -15.304 43.765 1.00 18.17 ? 143 ILE A O 1 ATOM 1061 C CB . ILE A 1 141 ? 78.642 -12.273 42.945 1.00 18.37 ? 143 ILE A CB 1 ATOM 1062 C CG1 . ILE A 1 141 ? 78.612 -12.099 41.427 1.00 19.32 ? 143 ILE A CG1 1 ATOM 1063 C CG2 . ILE A 1 141 ? 80.074 -12.406 43.442 1.00 19.46 ? 143 ILE A CG2 1 ATOM 1064 C CD1 . ILE A 1 141 ? 79.252 -10.810 40.956 1.00 19.50 ? 143 ILE A CD1 1 ATOM 1065 N N . SER A 1 142 ? 78.200 -15.300 41.809 1.00 18.94 ? 144 SER A N 1 ATOM 1066 C CA . SER A 1 142 ? 78.939 -16.421 41.234 1.00 18.72 ? 144 SER A CA 1 ATOM 1067 C C . SER A 1 142 ? 79.388 -16.097 39.816 1.00 18.34 ? 144 SER A C 1 ATOM 1068 O O . SER A 1 142 ? 78.591 -15.649 38.990 1.00 16.05 ? 144 SER A O 1 ATOM 1069 C CB . SER A 1 142 ? 78.081 -17.688 41.219 1.00 19.69 ? 144 SER A CB 1 ATOM 1070 O OG . SER A 1 142 ? 78.190 -18.392 42.443 1.00 22.53 ? 144 SER A OG 1 ATOM 1071 N N . LYS A 1 143 ? 80.664 -16.335 39.537 1.00 17.63 ? 145 LYS A N 1 ATOM 1072 C CA . LYS A 1 143 ? 81.182 -16.209 38.184 1.00 17.31 ? 145 LYS A CA 1 ATOM 1073 C C . LYS A 1 143 ? 80.862 -17.469 37.389 1.00 16.69 ? 145 LYS A C 1 ATOM 1074 O O . LYS A 1 143 ? 81.277 -18.567 37.761 1.00 17.24 ? 145 LYS A O 1 ATOM 1075 C CB . LYS A 1 143 ? 82.693 -15.977 38.213 1.00 19.22 ? 145 LYS A CB 1 ATOM 1076 C CG . LYS A 1 143 ? 83.358 -16.056 36.848 1.00 21.55 ? 145 LYS A CG 1 ATOM 1077 C CD . LYS A 1 143 ? 84.858 -15.842 36.960 1.00 25.90 ? 145 LYS A CD 1 ATOM 1078 C CE . LYS A 1 143 ? 85.603 -16.505 35.815 1.00 28.81 ? 145 LYS A CE 1 ATOM 1079 N NZ . LYS A 1 143 ? 87.078 -16.352 35.970 1.00 32.01 ? 145 LYS A NZ 1 ATOM 1080 N N . LEU A 1 144 ? 80.110 -17.313 36.305 1.00 13.89 ? 146 LEU A N 1 ATOM 1081 C CA . LEU A 1 144 ? 79.690 -18.461 35.509 1.00 13.27 ? 146 LEU A CA 1 ATOM 1082 C C . LEU A 1 144 ? 80.582 -18.642 34.288 1.00 12.27 ? 146 LEU A C 1 ATOM 1083 O O . LEU A 1 144 ? 80.796 -19.759 33.830 1.00 11.71 ? 146 LEU A O 1 ATOM 1084 C CB . LEU A 1 144 ? 78.231 -18.320 35.066 1.00 13.49 ? 146 LEU A CB 1 ATOM 1085 C CG . LEU A 1 144 ? 77.145 -18.234 36.139 1.00 13.54 ? 146 LEU A CG 1 ATOM 1086 C CD1 . LEU A 1 144 ? 75.779 -18.201 35.472 1.00 13.51 ? 146 LEU A CD1 1 ATOM 1087 C CD2 . LEU A 1 144 ? 77.239 -19.403 37.108 1.00 14.74 ? 146 LEU A CD2 1 ATOM 1088 N N . TYR A 1 145 ? 81.049 -17.529 33.733 1.00 11.98 ? 147 TYR A N 1 ATOM 1089 C CA . TYR A 1 145 ? 81.874 -17.541 32.529 1.00 11.55 ? 147 TYR A CA 1 ATOM 1090 C C . TYR A 1 145 ? 82.539 -16.181 32.402 1.00 12.02 ? 147 TYR A C 1 ATOM 1091 O O . TYR A 1 145 ? 82.036 -15.183 32.922 1.00 11.88 ? 147 TYR A O 1 ATOM 1092 C CB . TYR A 1 145 ? 81.015 -17.816 31.286 1.00 11.27 ? 147 TYR A CB 1 ATOM 1093 C CG . TYR A 1 145 ? 81.793 -17.856 29.980 1.00 10.77 ? 147 TYR A CG 1 ATOM 1094 C CD1 . TYR A 1 145 ? 82.820 -18.775 29.787 1.00 10.89 ? 147 TYR A CD1 1 ATOM 1095 C CD2 . TYR A 1 145 ? 81.472 -17.006 28.926 1.00 11.25 ? 147 TYR A CD2 1 ATOM 1096 C CE1 . TYR A 1 145 ? 83.514 -18.834 28.590 1.00 11.32 ? 147 TYR A CE1 1 ATOM 1097 C CE2 . TYR A 1 145 ? 82.177 -17.041 27.733 1.00 10.83 ? 147 TYR A CE2 1 ATOM 1098 C CZ . TYR A 1 145 ? 83.194 -17.961 27.567 1.00 11.49 ? 147 TYR A CZ 1 ATOM 1099 O OH . TYR A 1 145 ? 83.893 -18.011 26.376 1.00 11.70 ? 147 TYR A OH 1 ATOM 1100 N N . SER A 1 146 ? 83.683 -16.141 31.735 1.00 11.96 ? 148 SER A N 1 ATOM 1101 C CA . SER A 1 146 ? 84.294 -14.866 31.404 1.00 12.48 ? 148 SER A CA 1 ATOM 1102 C C . SER A 1 146 ? 85.043 -14.958 30.086 1.00 12.28 ? 148 SER A C 1 ATOM 1103 O O . SER A 1 146 ? 85.424 -16.044 29.651 1.00 11.97 ? 148 SER A O 1 ATOM 1104 C CB . SER A 1 146 ? 85.232 -14.408 32.523 1.00 12.80 ? 148 SER A CB 1 ATOM 1105 O OG . SER A 1 146 ? 86.386 -15.226 32.581 1.00 13.30 ? 148 SER A OG 1 ATOM 1106 N N . LEU A 1 147 ? 85.217 -13.813 29.439 1.00 11.25 ? 149 LEU A N 1 ATOM 1107 C CA . LEU A 1 147 ? 85.982 -13.745 28.207 1.00 10.86 ? 149 LEU A CA 1 ATOM 1108 C C . LEU A 1 147 ? 86.933 -12.553 28.243 1.00 10.99 ? 149 LEU A C 1 ATOM 1109 O O . LEU A 1 147 ? 86.505 -11.416 28.445 1.00 10.95 ? 149 LEU A O 1 ATOM 1110 C CB . LEU A 1 147 ? 85.038 -13.644 27.007 1.00 10.60 ? 149 LEU A CB 1 ATOM 1111 C CG . LEU A 1 147 ? 85.700 -13.668 25.628 1.00 10.20 ? 149 LEU A CG 1 ATOM 1112 C CD1 . LEU A 1 147 ? 86.438 -14.980 25.413 1.00 9.60 ? 149 LEU A CD1 1 ATOM 1113 C CD2 . LEU A 1 147 ? 84.677 -13.432 24.527 1.00 10.08 ? 149 LEU A CD2 1 ATOM 1114 N N . SER A 1 148 ? 88.225 -12.824 28.076 1.00 10.87 ? 150 SER A N 1 ATOM 1115 C CA . SER A 1 148 ? 89.235 -11.769 27.984 1.00 11.25 ? 150 SER A CA 1 ATOM 1116 C C . SER A 1 148 ? 89.414 -11.306 26.543 1.00 11.95 ? 150 SER A C 1 ATOM 1117 O O . SER A 1 148 ? 89.439 -12.119 25.620 1.00 13.64 ? 150 SER A O 1 ATOM 1118 C CB . SER A 1 148 ? 90.576 -12.260 28.539 1.00 11.93 ? 150 SER A CB 1 ATOM 1119 O OG . SER A 1 148 ? 90.471 -12.592 29.913 1.00 12.58 ? 150 SER A OG 1 ATOM 1120 N N . ALA A 1 149 ? 89.533 -9.996 26.356 1.00 11.41 ? 151 ALA A N 1 ATOM 1121 C CA . ALA A 1 149 ? 89.703 -9.412 25.032 1.00 10.82 ? 151 ALA A CA 1 ATOM 1122 C C . ALA A 1 149 ? 90.790 -8.342 25.089 1.00 10.73 ? 151 ALA A C 1 ATOM 1123 O O . ALA A 1 149 ? 91.129 -7.848 26.162 1.00 10.50 ? 151 ALA A O 1 ATOM 1124 C CB . ALA A 1 149 ? 88.392 -8.803 24.554 1.00 10.37 ? 151 ALA A CB 1 ATOM 1125 N N A SER A 1 150 ? 91.309 -7.961 23.929 0.50 11.28 ? 152 SER A N 1 ATOM 1126 N N B SER A 1 150 ? 91.355 -8.012 23.933 0.50 10.53 ? 152 SER A N 1 ATOM 1127 C CA A SER A 1 150 ? 92.311 -6.905 23.866 0.50 11.78 ? 152 SER A CA 1 ATOM 1128 C CA B SER A 1 150 ? 92.408 -7.006 23.862 0.50 10.77 ? 152 SER A CA 1 ATOM 1129 C C A SER A 1 150 ? 92.387 -6.281 22.482 0.50 11.89 ? 152 SER A C 1 ATOM 1130 C C B SER A 1 150 ? 92.454 -6.349 22.490 0.50 10.95 ? 152 SER A C 1 ATOM 1131 O O A SER A 1 150 ? 92.123 -6.940 21.477 0.50 11.93 ? 152 SER A O 1 ATOM 1132 O O B SER A 1 150 ? 92.153 -6.980 21.478 0.50 11.07 ? 152 SER A O 1 ATOM 1133 C CB A SER A 1 150 ? 93.682 -7.446 24.270 0.50 12.47 ? 152 SER A CB 1 ATOM 1134 C CB B SER A 1 150 ? 93.768 -7.627 24.193 0.50 11.22 ? 152 SER A CB 1 ATOM 1135 O OG A SER A 1 150 ? 93.870 -8.760 23.777 0.50 14.14 ? 152 SER A OG 1 ATOM 1136 O OG B SER A 1 150 ? 94.817 -6.684 24.040 0.50 10.14 ? 152 SER A OG 1 ATOM 1137 N N A ILE A 1 151 ? 92.737 -5.001 22.440 0.50 12.17 ? 153 ILE A N 1 ATOM 1138 N N B ILE A 1 151 ? 92.813 -5.070 22.468 0.50 11.21 ? 153 ILE A N 1 ATOM 1139 C CA A ILE A 1 151 ? 93.211 -4.390 21.210 0.50 12.68 ? 153 ILE A CA 1 ATOM 1140 C CA B ILE A 1 151 ? 93.219 -4.416 21.233 0.50 11.68 ? 153 ILE A CA 1 ATOM 1141 C C A ILE A 1 151 ? 94.394 -5.201 20.692 0.50 12.73 ? 153 ILE A C 1 ATOM 1142 C C B ILE A 1 151 ? 94.455 -5.123 20.685 0.50 12.28 ? 153 ILE A C 1 ATOM 1143 O O A ILE A 1 151 ? 95.174 -5.742 21.476 0.50 12.50 ? 153 ILE A O 1 ATOM 1144 O O B ILE A 1 151 ? 95.334 -5.526 21.448 0.50 12.39 ? 153 ILE A O 1 ATOM 1145 C CB A ILE A 1 151 ? 93.652 -2.933 21.444 0.50 12.95 ? 153 ILE A CB 1 ATOM 1146 C CB B ILE A 1 151 ? 93.534 -2.928 21.472 0.50 11.75 ? 153 ILE A CB 1 ATOM 1147 C CG1 A ILE A 1 151 ? 92.601 -2.186 22.270 0.50 13.54 ? 153 ILE A CG1 1 ATOM 1148 C CG1 B ILE A 1 151 ? 92.282 -2.195 21.963 0.50 11.84 ? 153 ILE A CG1 1 ATOM 1149 C CG2 A ILE A 1 151 ? 93.897 -2.228 20.119 0.50 13.00 ? 153 ILE A CG2 1 ATOM 1150 C CG2 B ILE A 1 151 ? 94.078 -2.284 20.205 0.50 11.79 ? 153 ILE A CG2 1 ATOM 1151 C CD1 A ILE A 1 151 ? 91.310 -1.920 21.528 0.50 14.67 ? 153 ILE A CD1 1 ATOM 1152 C CD1 B ILE A 1 151 ? 92.490 -0.717 22.216 0.50 12.43 ? 153 ILE A CD1 1 ATOM 1153 N N . ARG A 1 152 ? 94.489 -5.333 19.373 1.00 11.97 ? 154 ARG A N 1 ATOM 1154 C CA . ARG A 1 152 ? 95.560 -6.111 18.766 1.00 12.39 ? 154 ARG A CA 1 ATOM 1155 C C . ARG A 1 152 ? 96.871 -5.324 18.787 1.00 13.59 ? 154 ARG A C 1 ATOM 1156 O O . ARG A 1 152 ? 96.862 -4.109 18.991 1.00 13.63 ? 154 ARG A O 1 ATOM 1157 C CB . ARG A 1 152 ? 95.177 -6.553 17.352 1.00 11.74 ? 154 ARG A CB 1 ATOM 1158 C CG . ARG A 1 152 ? 94.033 -7.561 17.329 1.00 11.68 ? 154 ARG A CG 1 ATOM 1159 C CD . ARG A 1 152 ? 93.807 -8.133 15.939 1.00 11.78 ? 154 ARG A CD 1 ATOM 1160 N NE . ARG A 1 152 ? 95.029 -8.711 15.395 1.00 12.40 ? 154 ARG A NE 1 ATOM 1161 C CZ . ARG A 1 152 ? 95.428 -8.569 14.136 1.00 13.54 ? 154 ARG A CZ 1 ATOM 1162 N NH1 . ARG A 1 152 ? 94.700 -7.858 13.280 1.00 12.98 ? 154 ARG A NH1 1 ATOM 1163 N NH2 . ARG A 1 152 ? 96.576 -9.104 13.746 1.00 13.81 ? 154 ARG A NH2 1 ATOM 1164 N N . PRO A 1 153 ? 98.008 -6.028 18.674 1.00 14.91 ? 155 PRO A N 1 ATOM 1165 C CA . PRO A 1 153 ? 99.287 -5.390 18.989 1.00 17.17 ? 155 PRO A CA 1 ATOM 1166 C C . PRO A 1 153 ? 99.837 -4.526 17.856 1.00 17.92 ? 155 PRO A C 1 ATOM 1167 O O . PRO A 1 153 ? 99.495 -4.728 16.687 1.00 17.24 ? 155 PRO A O 1 ATOM 1168 C CB . PRO A 1 153 ? 100.219 -6.575 19.261 1.00 16.82 ? 155 PRO A CB 1 ATOM 1169 C CG . PRO A 1 153 ? 99.601 -7.723 18.541 1.00 17.16 ? 155 PRO A CG 1 ATOM 1170 C CD . PRO A 1 153 ? 98.121 -7.494 18.600 1.00 16.30 ? 155 PRO A CD 1 ATOM 1171 N N . GLY A 1 154 ? 100.663 -3.551 18.219 1.00 18.48 ? 156 GLY A N 1 ATOM 1172 C CA . GLY A 1 154 ? 101.468 -2.821 17.248 1.00 20.92 ? 156 GLY A CA 1 ATOM 1173 C C . GLY A 1 154 ? 100.643 -2.091 16.208 1.00 21.36 ? 156 GLY A C 1 ATOM 1174 O O . GLY A 1 154 ? 99.725 -1.343 16.541 1.00 22.51 ? 156 GLY A O 1 ATOM 1175 N N . ASN A 1 155 ? 100.974 -2.316 14.942 1.00 23.48 ? 157 ASN A N 1 ATOM 1176 C CA . ASN A 1 155 ? 100.324 -1.617 13.841 1.00 24.55 ? 157 ASN A CA 1 ATOM 1177 C C . ASN A 1 155 ? 98.930 -2.165 13.562 1.00 21.32 ? 157 ASN A C 1 ATOM 1178 O O . ASN A 1 155 ? 98.164 -1.582 12.795 1.00 22.03 ? 157 ASN A O 1 ATOM 1179 C CB . ASN A 1 155 ? 101.185 -1.697 12.579 1.00 26.98 ? 157 ASN A CB 1 ATOM 1180 C CG . ASN A 1 155 ? 102.476 -0.911 12.706 1.00 32.06 ? 157 ASN A CG 1 ATOM 1181 O OD1 . ASN A 1 155 ? 102.550 0.066 13.452 1.00 34.21 ? 157 ASN A OD1 1 ATOM 1182 N ND2 . ASN A 1 155 ? 103.501 -1.331 11.973 1.00 35.24 ? 157 ASN A ND2 1 ATOM 1183 N N . GLU A 1 156 ? 98.601 -3.283 14.197 1.00 19.17 ? 158 GLU A N 1 ATOM 1184 C CA . GLU A 1 156 ? 97.280 -3.878 14.046 1.00 17.26 ? 158 GLU A CA 1 ATOM 1185 C C . GLU A 1 156 ? 96.302 -3.383 15.107 1.00 15.07 ? 158 GLU A C 1 ATOM 1186 O O . GLU A 1 156 ? 95.163 -3.836 15.163 1.00 13.71 ? 158 GLU A O 1 ATOM 1187 C CB . GLU A 1 156 ? 97.366 -5.406 14.065 1.00 17.00 ? 158 GLU A CB 1 ATOM 1188 C CG . GLU A 1 156 ? 98.075 -6.004 12.857 1.00 18.51 ? 158 GLU A CG 1 ATOM 1189 C CD . GLU A 1 156 ? 97.278 -5.863 11.570 1.00 19.78 ? 158 GLU A CD 1 ATOM 1190 O OE1 . GLU A 1 156 ? 96.054 -6.098 11.589 1.00 18.90 ? 158 GLU A OE1 1 ATOM 1191 O OE2 . GLU A 1 156 ? 97.879 -5.536 10.527 1.00 21.03 ? 158 GLU A OE2 1 ATOM 1192 N N . ALA A 1 157 ? 96.743 -2.449 15.947 1.00 14.83 ? 159 ALA A N 1 ATOM 1193 C CA . ALA A 1 157 ? 95.834 -1.825 16.907 1.00 14.66 ? 159 ALA A CA 1 ATOM 1194 C C . ALA A 1 157 ? 94.656 -1.174 16.186 1.00 14.50 ? 159 ALA A C 1 ATOM 1195 O O . ALA A 1 157 ? 94.841 -0.354 15.283 1.00 13.73 ? 159 ALA A O 1 ATOM 1196 C CB . ALA A 1 157 ? 96.567 -0.804 17.766 1.00 14.57 ? 159 ALA A CB 1 ATOM 1197 N N . GLY A 1 158 ? 93.444 -1.543 16.587 1.00 12.93 ? 160 GLY A N 1 ATOM 1198 C CA . GLY A 1 158 ? 92.241 -1.021 15.948 1.00 12.57 ? 160 GLY A CA 1 ATOM 1199 C C . GLY A 1 158 ? 91.733 -1.927 14.842 1.00 12.88 ? 160 GLY A C 1 ATOM 1200 O O . GLY A 1 158 ? 90.630 -1.737 14.331 1.00 13.20 ? 160 GLY A O 1 ATOM 1201 N N . HIS A 1 159 ? 92.529 -2.930 14.487 1.00 12.28 ? 161 HIS A N 1 ATOM 1202 C CA . HIS A 1 159 ? 92.110 -3.927 13.502 1.00 12.78 ? 161 HIS A CA 1 ATOM 1203 C C . HIS A 1 159 ? 91.535 -5.161 14.201 1.00 11.86 ? 161 HIS A C 1 ATOM 1204 O O . HIS A 1 159 ? 91.954 -5.513 15.301 1.00 12.16 ? 161 HIS A O 1 ATOM 1205 C CB . HIS A 1 159 ? 93.292 -4.320 12.608 1.00 12.93 ? 161 HIS A CB 1 ATOM 1206 C CG . HIS A 1 159 ? 93.879 -3.174 11.843 1.00 13.30 ? 161 HIS A CG 1 ATOM 1207 N ND1 . HIS A 1 159 ? 93.902 -3.133 10.466 1.00 13.86 ? 161 HIS A ND1 1 ATOM 1208 C CD2 . HIS A 1 159 ? 94.460 -2.023 12.262 1.00 13.43 ? 161 HIS A CD2 1 ATOM 1209 C CE1 . HIS A 1 159 ? 94.466 -2.005 10.069 1.00 14.00 ? 161 HIS A CE1 1 ATOM 1210 N NE2 . HIS A 1 159 ? 94.820 -1.317 11.139 1.00 13.71 ? 161 HIS A NE2 1 ATOM 1211 N N . GLU A 1 160 ? 90.556 -5.807 13.578 1.00 12.23 ? 162 GLU A N 1 ATOM 1212 C CA . GLU A 1 160 ? 90.069 -7.076 14.110 1.00 11.95 ? 162 GLU A CA 1 ATOM 1213 C C . GLU A 1 160 ? 90.886 -8.240 13.553 1.00 11.23 ? 162 GLU A C 1 ATOM 1214 O O . GLU A 1 160 ? 91.880 -8.025 12.856 1.00 10.60 ? 162 GLU A O 1 ATOM 1215 C CB . GLU A 1 160 ? 88.569 -7.254 13.865 1.00 12.26 ? 162 GLU A CB 1 ATOM 1216 C CG . GLU A 1 160 ? 88.142 -7.062 12.425 1.00 13.26 ? 162 GLU A CG 1 ATOM 1217 C CD . GLU A 1 160 ? 88.725 -8.121 11.519 1.00 13.39 ? 162 GLU A CD 1 ATOM 1218 O OE1 . GLU A 1 160 ? 88.385 -9.310 11.704 1.00 15.18 ? 162 GLU A OE1 1 ATOM 1219 O OE2 . GLU A 1 160 ? 89.542 -7.767 10.643 1.00 13.68 ? 162 GLU A OE2 1 ATOM 1220 N N . MET A 1 161 ? 90.519 -9.464 13.922 1.00 11.04 ? 163 MET A N 1 ATOM 1221 C CA . MET A 1 161 ? 91.410 -10.605 13.723 1.00 10.99 ? 163 MET A CA 1 ATOM 1222 C C . MET A 1 161 ? 91.661 -10.936 12.249 1.00 10.70 ? 163 MET A C 1 ATOM 1223 O O . MET A 1 161 ? 92.680 -11.539 11.917 1.00 10.91 ? 163 MET A O 1 ATOM 1224 C CB . MET A 1 161 ? 90.914 -11.837 14.487 1.00 11.19 ? 163 MET A CB 1 ATOM 1225 C CG . MET A 1 161 ? 91.263 -11.837 15.974 1.00 11.40 ? 163 MET A CG 1 ATOM 1226 S SD . MET A 1 161 ? 93.029 -12.026 16.294 1.00 12.63 ? 163 MET A SD 1 ATOM 1227 C CE . MET A 1 161 ? 93.101 -11.890 18.083 1.00 11.41 ? 163 MET A CE 1 ATOM 1228 N N . PHE A 1 162 ? 90.732 -10.564 11.371 1.00 11.08 ? 164 PHE A N 1 ATOM 1229 C CA . PHE A 1 162 ? 90.927 -10.785 9.935 1.00 11.05 ? 164 PHE A CA 1 ATOM 1230 C C . PHE A 1 162 ? 91.925 -9.787 9.357 1.00 11.20 ? 164 PHE A C 1 ATOM 1231 O O . PHE A 1 162 ? 92.396 -9.958 8.232 1.00 12.71 ? 164 PHE A O 1 ATOM 1232 C CB . PHE A 1 162 ? 89.607 -10.680 9.160 1.00 10.93 ? 164 PHE A CB 1 ATOM 1233 C CG . PHE A 1 162 ? 88.722 -11.889 9.282 1.00 10.30 ? 164 PHE A CG 1 ATOM 1234 C CD1 . PHE A 1 162 ? 89.263 -13.156 9.440 1.00 10.14 ? 164 PHE A CD1 1 ATOM 1235 C CD2 . PHE A 1 162 ? 87.346 -11.760 9.190 1.00 10.28 ? 164 PHE A CD2 1 ATOM 1236 C CE1 . PHE A 1 162 ? 88.443 -14.261 9.573 1.00 9.93 ? 164 PHE A CE1 1 ATOM 1237 C CE2 . PHE A 1 162 ? 86.521 -12.864 9.300 1.00 10.18 ? 164 PHE A CE2 1 ATOM 1238 C CZ . PHE A 1 162 ? 87.071 -14.116 9.493 1.00 9.98 ? 164 PHE A CZ 1 ATOM 1239 N N . GLY A 1 163 ? 92.175 -8.703 10.088 1.00 11.00 ? 165 GLY A N 1 ATOM 1240 C CA . GLY A 1 163 ? 93.169 -7.713 9.674 1.00 11.46 ? 165 GLY A CA 1 ATOM 1241 C C . GLY A 1 163 ? 92.602 -6.354 9.301 1.00 11.20 ? 165 GLY A C 1 ATOM 1242 O O . GLY A 1 163 ? 93.348 -5.434 8.963 1.00 11.33 ? 165 GLY A O 1 ATOM 1243 N N . PHE A 1 164 ? 91.282 -6.215 9.380 1.00 10.25 ? 166 PHE A N 1 ATOM 1244 C CA . PHE A 1 164 ? 90.614 -5.019 8.873 1.00 9.67 ? 166 PHE A CA 1 ATOM 1245 C C . PHE A 1 164 ? 90.441 -3.977 9.969 1.00 10.09 ? 166 PHE A C 1 ATOM 1246 O O . PHE A 1 164 ? 90.092 -4.317 11.098 1.00 10.04 ? 166 PHE A O 1 ATOM 1247 C CB . PHE A 1 164 ? 89.253 -5.382 8.277 1.00 9.36 ? 166 PHE A CB 1 ATOM 1248 C CG . PHE A 1 164 ? 89.345 -6.195 7.019 1.00 9.08 ? 166 PHE A CG 1 ATOM 1249 C CD1 . PHE A 1 164 ? 89.592 -7.557 7.076 1.00 8.79 ? 166 PHE A CD1 1 ATOM 1250 C CD2 . PHE A 1 164 ? 89.234 -5.590 5.780 1.00 8.79 ? 166 PHE A CD2 1 ATOM 1251 C CE1 . PHE A 1 164 ? 89.696 -8.306 5.919 1.00 8.52 ? 166 PHE A CE1 1 ATOM 1252 C CE2 . PHE A 1 164 ? 89.338 -6.331 4.619 1.00 8.57 ? 166 PHE A CE2 1 ATOM 1253 C CZ . PHE A 1 164 ? 89.578 -7.690 4.689 1.00 8.43 ? 166 PHE A CZ 1 ATOM 1254 N N . LEU A 1 165 ? 90.711 -2.716 9.640 1.00 10.26 ? 167 LEU A N 1 ATOM 1255 C CA . LEU A 1 165 ? 90.427 -1.619 10.553 1.00 11.56 ? 167 LEU A CA 1 ATOM 1256 C C . LEU A 1 165 ? 88.945 -1.609 10.898 1.00 12.87 ? 167 LEU A C 1 ATOM 1257 O O . LEU A 1 165 ? 88.086 -1.698 10.015 1.00 11.82 ? 167 LEU A O 1 ATOM 1258 C CB . LEU A 1 165 ? 90.839 -0.271 9.951 1.00 11.80 ? 167 LEU A CB 1 ATOM 1259 C CG . LEU A 1 165 ? 90.805 0.939 10.894 1.00 12.00 ? 167 LEU A CG 1 ATOM 1260 C CD1 . LEU A 1 165 ? 91.851 0.811 11.991 1.00 12.08 ? 167 LEU A CD1 1 ATOM 1261 C CD2 . LEU A 1 165 ? 91.009 2.229 10.112 1.00 11.76 ? 167 LEU A CD2 1 ATOM 1262 N N A ASP A 1 166 ? 88.657 -1.468 12.188 0.50 13.79 ? 168 ASP A N 1 ATOM 1263 N N B ASP A 1 166 ? 88.646 -1.553 12.188 0.50 14.18 ? 168 ASP A N 1 ATOM 1264 C CA A ASP A 1 166 ? 87.302 -1.602 12.708 0.50 15.96 ? 168 ASP A CA 1 ATOM 1265 C CA B ASP A 1 166 ? 87.265 -1.562 12.638 0.50 16.19 ? 168 ASP A CA 1 ATOM 1266 C C A ASP A 1 166 ? 86.962 -0.421 13.617 0.50 17.28 ? 168 ASP A C 1 ATOM 1267 C C B ASP A 1 166 ? 86.923 -0.250 13.330 0.50 17.18 ? 168 ASP A C 1 ATOM 1268 O O A ASP A 1 166 ? 87.856 0.218 14.176 0.50 19.33 ? 168 ASP A O 1 ATOM 1269 O O B ASP A 1 166 ? 87.767 0.640 13.451 0.50 18.01 ? 168 ASP A O 1 ATOM 1270 C CB A ASP A 1 166 ? 87.167 -2.917 13.480 0.50 17.12 ? 168 ASP A CB 1 ATOM 1271 C CB B ASP A 1 166 ? 87.018 -2.741 13.580 0.50 17.28 ? 168 ASP A CB 1 ATOM 1272 C CG A ASP A 1 166 ? 85.739 -3.209 13.888 0.50 18.07 ? 168 ASP A CG 1 ATOM 1273 C CG B ASP A 1 166 ? 87.713 -2.573 14.912 0.50 17.14 ? 168 ASP A CG 1 ATOM 1274 O OD1 A ASP A 1 166 ? 84.820 -2.554 13.350 0.50 17.87 ? 168 ASP A OD1 1 ATOM 1275 O OD1 B ASP A 1 166 ? 87.768 -1.431 15.415 0.50 18.35 ? 168 ASP A OD1 1 ATOM 1276 O OD2 A ASP A 1 166 ? 85.539 -4.091 14.749 0.50 19.61 ? 168 ASP A OD2 1 ATOM 1277 O OD2 B ASP A 1 166 ? 88.200 -3.583 15.459 0.50 19.34 ? 168 ASP A OD2 1 ATOM 1278 N N . GLY A 1 167 ? 85.673 -0.127 13.754 1.00 17.66 ? 169 GLY A N 1 ATOM 1279 C CA . GLY A 1 167 ? 85.235 1.033 14.523 1.00 18.40 ? 169 GLY A CA 1 ATOM 1280 C C . GLY A 1 167 ? 85.336 2.344 13.764 1.00 18.82 ? 169 GLY A C 1 ATOM 1281 O O . GLY A 1 167 ? 85.506 3.405 14.364 1.00 20.15 ? 169 GLY A O 1 ATOM 1282 N N . ILE A 1 168 ? 85.214 2.278 12.443 1.00 16.10 ? 170 ILE A N 1 ATOM 1283 C CA . ILE A 1 168 ? 85.121 3.483 11.628 1.00 15.22 ? 170 ILE A CA 1 ATOM 1284 C C . ILE A 1 168 ? 83.703 4.053 11.661 1.00 14.55 ? 170 ILE A C 1 ATOM 1285 O O . ILE A 1 168 ? 83.511 5.253 11.844 1.00 14.38 ? 170 ILE A O 1 ATOM 1286 C CB . ILE A 1 168 ? 85.505 3.198 10.162 1.00 15.13 ? 170 ILE A CB 1 ATOM 1287 C CG1 . ILE A 1 168 ? 86.952 2.707 10.073 1.00 16.06 ? 170 ILE A CG1 1 ATOM 1288 C CG2 . ILE A 1 168 ? 85.282 4.432 9.300 1.00 14.51 ? 170 ILE A CG2 1 ATOM 1289 C CD1 . ILE A 1 168 ? 87.285 2.013 8.767 1.00 15.11 ? 170 ILE A CD1 1 ATOM 1290 N N . ALA A 1 169 ? 82.716 3.183 11.460 1.00 12.82 ? 171 ALA A N 1 ATOM 1291 C CA . ALA A 1 169 ? 81.347 3.614 11.193 1.00 12.43 ? 171 ALA A CA 1 ATOM 1292 C C . ALA A 1 169 ? 80.452 3.445 12.417 1.00 11.52 ? 171 ALA A C 1 ATOM 1293 O O . ALA A 1 169 ? 80.355 2.358 12.981 1.00 11.69 ? 171 ALA A O 1 ATOM 1294 C CB . ALA A 1 169 ? 80.776 2.845 10.012 1.00 12.10 ? 171 ALA A CB 1 ATOM 1295 N N . GLN A 1 170 ? 79.820 4.536 12.838 1.00 10.71 ? 172 GLN A N 1 ATOM 1296 C CA . GLN A 1 170 ? 78.804 4.487 13.885 1.00 10.57 ? 172 GLN A CA 1 ATOM 1297 C C . GLN A 1 170 ? 77.728 5.503 13.532 1.00 10.41 ? 172 GLN A C 1 ATOM 1298 O O . GLN A 1 170 ? 78.011 6.488 12.851 1.00 10.46 ? 172 GLN A O 1 ATOM 1299 C CB . GLN A 1 170 ? 79.410 4.856 15.244 1.00 10.27 ? 172 GLN A CB 1 ATOM 1300 C CG . GLN A 1 170 ? 80.687 4.116 15.604 1.00 11.41 ? 172 GLN A CG 1 ATOM 1301 C CD . GLN A 1 170 ? 80.419 2.786 16.278 1.00 11.84 ? 172 GLN A CD 1 ATOM 1302 O OE1 . GLN A 1 170 ? 79.294 2.287 16.269 1.00 11.20 ? 172 GLN A OE1 1 ATOM 1303 N NE2 . GLN A 1 170 ? 81.460 2.196 16.857 1.00 13.92 ? 172 GLN A NE2 1 ATOM 1304 N N . PRO A 1 171 ? 76.492 5.278 13.999 1.00 10.23 ? 173 PRO A N 1 ATOM 1305 C CA . PRO A 1 171 ? 75.502 6.336 13.824 1.00 10.47 ? 173 PRO A CA 1 ATOM 1306 C C . PRO A 1 171 ? 75.878 7.550 14.663 1.00 10.94 ? 173 PRO A C 1 ATOM 1307 O O . PRO A 1 171 ? 76.412 7.405 15.765 1.00 10.84 ? 173 PRO A O 1 ATOM 1308 C CB . PRO A 1 171 ? 74.209 5.700 14.344 1.00 10.22 ? 173 PRO A CB 1 ATOM 1309 C CG . PRO A 1 171 ? 74.666 4.665 15.320 1.00 10.26 ? 173 PRO A CG 1 ATOM 1310 C CD . PRO A 1 171 ? 75.977 4.147 14.790 1.00 9.85 ? 173 PRO A CD 1 ATOM 1311 N N . ALA A 1 172 ? 75.660 8.741 14.117 1.00 11.56 ? 174 ALA A N 1 ATOM 1312 C CA . ALA A 1 172 ? 75.736 9.954 14.916 1.00 12.36 ? 174 ALA A CA 1 ATOM 1313 C C . ALA A 1 172 ? 74.375 10.220 15.547 1.00 13.08 ? 174 ALA A C 1 ATOM 1314 O O . ALA A 1 172 ? 73.344 10.106 14.885 1.00 12.82 ? 174 ALA A O 1 ATOM 1315 C CB . ALA A 1 172 ? 76.160 11.134 14.054 1.00 12.68 ? 174 ALA A CB 1 ATOM 1316 N N A ILE A 1 173 ? 74.384 10.577 16.827 0.50 13.59 ? 175 ILE A N 1 ATOM 1317 N N B ILE A 1 173 ? 74.372 10.564 16.830 0.50 13.55 ? 175 ILE A N 1 ATOM 1318 C CA A ILE A 1 173 ? 73.163 10.917 17.545 0.50 14.17 ? 175 ILE A CA 1 ATOM 1319 C CA B ILE A 1 173 ? 73.133 10.893 17.524 0.50 14.09 ? 175 ILE A CA 1 ATOM 1320 C C A ILE A 1 173 ? 72.851 12.404 17.395 0.50 14.86 ? 175 ILE A C 1 ATOM 1321 C C B ILE A 1 173 ? 72.825 12.385 17.431 0.50 14.86 ? 175 ILE A C 1 ATOM 1322 O O A ILE A 1 173 ? 73.627 13.254 17.829 0.50 15.25 ? 175 ILE A O 1 ATOM 1323 O O B ILE A 1 173 ? 73.584 13.218 17.924 0.50 15.43 ? 175 ILE A O 1 ATOM 1324 C CB A ILE A 1 173 ? 73.291 10.587 19.043 0.50 13.99 ? 175 ILE A CB 1 ATOM 1325 C CB B ILE A 1 173 ? 73.177 10.462 19.002 0.50 13.77 ? 175 ILE A CB 1 ATOM 1326 C CG1 A ILE A 1 173 ? 73.813 9.161 19.233 0.50 14.81 ? 175 ILE A CG1 1 ATOM 1327 C CG1 B ILE A 1 173 ? 73.026 8.942 19.116 0.50 13.93 ? 175 ILE A CG1 1 ATOM 1328 C CG2 A ILE A 1 173 ? 71.958 10.786 19.749 0.50 13.60 ? 175 ILE A CG2 1 ATOM 1329 C CG2 B ILE A 1 173 ? 72.082 11.164 19.792 0.50 13.99 ? 175 ILE A CG2 1 ATOM 1330 C CD1 A ILE A 1 173 ? 72.907 8.095 18.656 0.50 14.09 ? 175 ILE A CD1 1 ATOM 1331 C CD1 B ILE A 1 173 ? 73.152 8.418 20.529 0.50 12.74 ? 175 ILE A CD1 1 ATOM 1332 N N . ASN A 1 174 ? 71.719 12.709 16.770 1.00 15.26 ? 176 ASN A N 1 ATOM 1333 C CA . ASN A 1 174 ? 71.307 14.096 16.566 1.00 17.05 ? 176 ASN A CA 1 ATOM 1334 C C . ASN A 1 174 ? 71.307 14.878 17.877 1.00 17.64 ? 176 ASN A C 1 ATOM 1335 O O . ASN A 1 174 ? 70.764 14.420 18.882 1.00 17.88 ? 176 ASN A O 1 ATOM 1336 C CB . ASN A 1 174 ? 69.919 14.141 15.920 1.00 18.89 ? 176 ASN A CB 1 ATOM 1337 C CG . ASN A 1 174 ? 69.548 15.525 15.424 1.00 21.62 ? 176 ASN A CG 1 ATOM 1338 O OD1 . ASN A 1 174 ? 70.394 16.270 14.926 1.00 21.37 ? 176 ASN A OD1 1 ATOM 1339 N ND2 . ASN A 1 174 ? 68.271 15.873 15.548 1.00 21.28 ? 176 ASN A ND2 1 ATOM 1340 N N . GLY A 1 175 ? 71.966 16.032 17.878 1.00 18.32 ? 177 GLY A N 1 ATOM 1341 C CA . GLY A 1 175 ? 72.024 16.873 19.068 1.00 19.19 ? 177 GLY A CA 1 ATOM 1342 C C . GLY A 1 175 ? 73.137 16.492 20.027 1.00 20.14 ? 177 GLY A C 1 ATOM 1343 O O . GLY A 1 175 ? 73.399 17.206 20.992 1.00 21.93 ? 177 GLY A O 1 ATOM 1344 N N . PHE A 1 176 ? 73.793 15.363 19.763 1.00 18.52 ? 178 PHE A N 1 ATOM 1345 C CA . PHE A 1 176 ? 74.922 14.926 20.577 1.00 18.10 ? 178 PHE A CA 1 ATOM 1346 C C . PHE A 1 176 ? 76.229 14.928 19.792 1.00 18.67 ? 178 PHE A C 1 ATOM 1347 O O . PHE A 1 176 ? 77.177 15.630 20.147 1.00 16.88 ? 178 PHE A O 1 ATOM 1348 C CB . PHE A 1 176 ? 74.665 13.533 21.153 1.00 19.26 ? 178 PHE A CB 1 ATOM 1349 C CG . PHE A 1 176 ? 75.789 13.015 22.005 1.00 20.25 ? 178 PHE A CG 1 ATOM 1350 C CD1 . PHE A 1 176 ? 76.185 13.699 23.141 1.00 20.24 ? 178 PHE A CD1 1 ATOM 1351 C CD2 . PHE A 1 176 ? 76.445 11.840 21.672 1.00 19.31 ? 178 PHE A CD2 1 ATOM 1352 C CE1 . PHE A 1 176 ? 77.220 13.226 23.928 1.00 21.27 ? 178 PHE A CE1 1 ATOM 1353 C CE2 . PHE A 1 176 ? 77.481 11.362 22.453 1.00 19.94 ? 178 PHE A CE2 1 ATOM 1354 C CZ . PHE A 1 176 ? 77.867 12.054 23.584 1.00 20.34 ? 178 PHE A CZ 1 ATOM 1355 N N . ASN A 1 177 ? 76.287 14.112 18.743 1.00 17.92 ? 179 ASN A N 1 ATOM 1356 C CA . ASN A 1 177 ? 77.472 14.040 17.895 1.00 18.70 ? 179 ASN A CA 1 ATOM 1357 C C . ASN A 1 177 ? 77.446 15.126 16.827 1.00 19.43 ? 179 ASN A C 1 ATOM 1358 O O . ASN A 1 177 ? 76.393 15.441 16.280 1.00 21.89 ? 179 ASN A O 1 ATOM 1359 C CB . ASN A 1 177 ? 77.570 12.666 17.223 1.00 18.42 ? 179 ASN A CB 1 ATOM 1360 C CG . ASN A 1 177 ? 77.643 11.524 18.221 1.00 19.41 ? 179 ASN A CG 1 ATOM 1361 O OD1 . ASN A 1 177 ? 76.742 10.689 18.292 1.00 17.98 ? 179 ASN A OD1 1 ATOM 1362 N ND2 . ASN A 1 177 ? 78.738 11.460 18.972 1.00 20.06 ? 179 ASN A ND2 1 ATOM 1363 N N . THR A 1 178 ? 78.605 15.704 16.538 1.00 19.97 ? 180 THR A N 1 ATOM 1364 C CA . THR A 1 178 ? 78.772 16.465 15.309 1.00 20.39 ? 180 THR A CA 1 ATOM 1365 C C . THR A 1 178 ? 79.149 15.504 14.191 1.00 19.47 ? 180 THR A C 1 ATOM 1366 O O . THR A 1 178 ? 80.207 14.880 14.236 1.00 19.39 ? 180 THR A O 1 ATOM 1367 C CB . THR A 1 178 ? 79.860 17.546 15.453 1.00 22.21 ? 180 THR A CB 1 ATOM 1368 O OG1 . THR A 1 178 ? 79.452 18.505 16.437 1.00 23.19 ? 180 THR A OG1 1 ATOM 1369 C CG2 . THR A 1 178 ? 80.081 18.257 14.123 1.00 23.22 ? 180 THR A CG2 1 ATOM 1370 N N . PRO A 1 179 ? 78.251 15.335 13.214 1.00 18.73 ? 181 PRO A N 1 ATOM 1371 C CA . PRO A 1 179 ? 78.361 14.242 12.253 1.00 17.94 ? 181 PRO A CA 1 ATOM 1372 C C . PRO A 1 179 ? 79.592 14.369 11.363 1.00 17.45 ? 181 PRO A C 1 ATOM 1373 O O . PRO A 1 179 ? 80.018 15.480 11.044 1.00 16.97 ? 181 PRO A O 1 ATOM 1374 C CB . PRO A 1 179 ? 77.083 14.379 11.417 1.00 17.93 ? 181 PRO A CB 1 ATOM 1375 C CG . PRO A 1 179 ? 76.132 15.123 12.294 1.00 18.05 ? 181 PRO A CG 1 ATOM 1376 C CD . PRO A 1 179 ? 76.992 16.082 13.059 1.00 18.42 ? 181 PRO A CD 1 ATOM 1377 N N . LEU A 1 180 ? 80.175 13.229 11.005 1.00 15.33 ? 182 LEU A N 1 ATOM 1378 C CA . LEU A 1 180 ? 81.247 13.177 10.017 1.00 15.42 ? 182 LEU A CA 1 ATOM 1379 C C . LEU A 1 180 ? 80.666 13.003 8.619 1.00 13.99 ? 182 LEU A C 1 ATOM 1380 O O . LEU A 1 180 ? 79.542 12.529 8.466 1.00 13.76 ? 182 LEU A O 1 ATOM 1381 C CB . LEU A 1 180 ? 82.189 12.013 10.324 1.00 15.15 ? 182 LEU A CB 1 ATOM 1382 C CG . LEU A 1 180 ? 82.863 12.039 11.697 1.00 16.14 ? 182 LEU A CG 1 ATOM 1383 C CD1 . LEU A 1 180 ? 83.310 10.641 12.102 1.00 15.68 ? 182 LEU A CD1 1 ATOM 1384 C CD2 . LEU A 1 180 ? 84.037 13.007 11.692 1.00 16.32 ? 182 LEU A CD2 1 ATOM 1385 N N . PRO A 1 181 ? 81.444 13.362 7.589 1.00 13.97 ? 183 PRO A N 1 ATOM 1386 C CA . PRO A 1 181 ? 80.973 13.218 6.217 1.00 13.93 ? 183 PRO A CA 1 ATOM 1387 C C . PRO A 1 181 ? 80.518 11.792 5.905 1.00 13.13 ? 183 PRO A C 1 ATOM 1388 O O . PRO A 1 181 ? 81.298 10.848 6.048 1.00 14.01 ? 183 PRO A O 1 ATOM 1389 C CB . PRO A 1 181 ? 82.209 13.573 5.394 1.00 13.62 ? 183 PRO A CB 1 ATOM 1390 C CG . PRO A 1 181 ? 82.935 14.564 6.242 1.00 13.57 ? 183 PRO A CG 1 ATOM 1391 C CD . PRO A 1 181 ? 82.692 14.144 7.670 1.00 13.97 ? 183 PRO A CD 1 ATOM 1392 N N . GLY A 1 182 ? 79.263 11.647 5.492 1.00 12.47 ? 184 GLY A N 1 ATOM 1393 C CA . GLY A 1 182 ? 78.711 10.343 5.125 1.00 11.44 ? 184 GLY A CA 1 ATOM 1394 C C . GLY A 1 182 ? 78.014 9.625 6.268 1.00 11.14 ? 184 GLY A C 1 ATOM 1395 O O . GLY A 1 182 ? 77.237 8.698 6.046 1.00 11.36 ? 184 GLY A O 1 ATOM 1396 N N . GLN A 1 183 ? 78.296 10.051 7.495 1.00 11.27 ? 185 GLN A N 1 ATOM 1397 C CA . GLN A 1 183 ? 77.779 9.384 8.687 1.00 11.33 ? 185 GLN A CA 1 ATOM 1398 C C . GLN A 1 183 ? 76.260 9.524 8.772 1.00 11.88 ? 185 GLN A C 1 ATOM 1399 O O . GLN A 1 183 ? 75.718 10.598 8.518 1.00 11.54 ? 185 GLN A O 1 ATOM 1400 C CB . GLN A 1 183 ? 78.422 9.986 9.940 1.00 11.73 ? 185 GLN A CB 1 ATOM 1401 C CG . GLN A 1 183 ? 78.318 9.120 11.182 1.00 12.19 ? 185 GLN A CG 1 ATOM 1402 C CD . GLN A 1 183 ? 78.920 9.777 12.414 1.00 13.20 ? 185 GLN A CD 1 ATOM 1403 O OE1 . GLN A 1 183 ? 79.284 10.956 12.396 1.00 13.73 ? 185 GLN A OE1 1 ATOM 1404 N NE2 . GLN A 1 183 ? 79.021 9.016 13.497 1.00 11.84 ? 185 GLN A NE2 1 ATOM 1405 N N . ASN A 1 184 ? 75.573 8.445 9.142 1.00 12.10 ? 186 ASN A N 1 ATOM 1406 C CA . ASN A 1 184 ? 74.130 8.523 9.380 1.00 12.41 ? 186 ASN A CA 1 ATOM 1407 C C . ASN A 1 184 ? 73.820 9.327 10.641 1.00 13.18 ? 186 ASN A C 1 ATOM 1408 O O . ASN A 1 184 ? 74.633 9.396 11.562 1.00 12.21 ? 186 ASN A O 1 ATOM 1409 C CB . ASN A 1 184 ? 73.501 7.127 9.466 1.00 11.92 ? 186 ASN A CB 1 ATOM 1410 C CG . ASN A 1 184 ? 72.043 7.112 9.031 1.00 12.46 ? 186 ASN A CG 1 ATOM 1411 O OD1 . ASN A 1 184 ? 71.437 8.161 8.811 1.00 12.13 ? 186 ASN A OD1 1 ATOM 1412 N ND2 . ASN A 1 184 ? 71.479 5.916 8.884 1.00 12.37 ? 186 ASN A ND2 1 ATOM 1413 N N . ILE A 1 185 ? 72.653 9.964 10.654 1.00 14.11 ? 187 ILE A N 1 ATOM 1414 C CA . ILE A 1 185 ? 72.231 10.781 11.785 1.00 14.40 ? 187 ILE A CA 1 ATOM 1415 C C . ILE A 1 185 ? 70.872 10.293 12.270 1.00 14.51 ? 187 ILE A C 1 ATOM 1416 O O . ILE A 1 185 ? 69.922 10.211 11.493 1.00 14.53 ? 187 ILE A O 1 ATOM 1417 C CB . ILE A 1 185 ? 72.134 12.270 11.394 1.00 14.76 ? 187 ILE A CB 1 ATOM 1418 C CG1 . ILE A 1 185 ? 73.471 12.758 10.827 1.00 14.94 ? 187 ILE A CG1 1 ATOM 1419 C CG2 . ILE A 1 185 ? 71.716 13.113 12.589 1.00 14.10 ? 187 ILE A CG2 1 ATOM 1420 C CD1 . ILE A 1 185 ? 73.369 14.062 10.064 1.00 16.59 ? 187 ILE A CD1 1 ATOM 1421 N N . VAL A 1 186 ? 70.796 9.922 13.543 1.00 14.07 ? 188 VAL A N 1 ATOM 1422 C CA . VAL A 1 186 ? 69.613 9.245 14.066 1.00 13.79 ? 188 VAL A CA 1 ATOM 1423 C C . VAL A 1 186 ? 69.132 9.889 15.360 1.00 13.76 ? 188 VAL A C 1 ATOM 1424 O O . VAL A 1 186 ? 69.890 10.577 16.041 1.00 13.99 ? 188 VAL A O 1 ATOM 1425 C CB . VAL A 1 186 ? 69.880 7.746 14.325 1.00 13.61 ? 188 VAL A CB 1 ATOM 1426 C CG1 . VAL A 1 186 ? 70.439 7.079 13.079 1.00 13.46 ? 188 VAL A CG1 1 ATOM 1427 C CG2 . VAL A 1 186 ? 70.831 7.567 15.500 1.00 13.33 ? 188 VAL A CG2 1 ATOM 1428 N N . ASP A 1 187 ? 67.865 9.661 15.691 1.00 14.52 ? 189 ASP A N 1 ATOM 1429 C CA . ASP A 1 187 ? 67.325 10.068 16.982 1.00 14.11 ? 189 ASP A CA 1 ATOM 1430 C C . ASP A 1 187 ? 68.001 9.287 18.105 1.00 12.86 ? 189 ASP A C 1 ATOM 1431 O O . ASP A 1 187 ? 68.323 8.109 17.948 1.00 12.19 ? 189 ASP A O 1 ATOM 1432 C CB . ASP A 1 187 ? 65.814 9.829 17.026 1.00 15.74 ? 189 ASP A CB 1 ATOM 1433 C CG . ASP A 1 187 ? 65.043 10.764 16.107 1.00 18.34 ? 189 ASP A CG 1 ATOM 1434 O OD1 . ASP A 1 187 ? 65.440 11.941 15.980 1.00 20.36 ? 189 ASP A OD1 1 ATOM 1435 O OD2 . ASP A 1 187 ? 64.025 10.324 15.531 1.00 19.43 ? 189 ASP A OD2 1 ATOM 1436 N N . ALA A 1 188 ? 68.222 9.949 19.235 1.00 11.92 ? 190 ALA A N 1 ATOM 1437 C CA . ALA A 1 188 ? 68.847 9.305 20.385 1.00 11.18 ? 190 ALA A CA 1 ATOM 1438 C C . ALA A 1 188 ? 68.099 8.038 20.794 1.00 10.81 ? 190 ALA A C 1 ATOM 1439 O O . ALA A 1 188 ? 68.705 7.069 21.254 1.00 9.82 ? 190 ALA A O 1 ATOM 1440 C CB . ALA A 1 188 ? 68.930 10.271 21.555 1.00 10.91 ? 190 ALA A CB 1 ATOM 1441 N N . GLY A 1 189 ? 66.780 8.056 20.624 1.00 10.56 ? 191 GLY A N 1 ATOM 1442 C CA . GLY A 1 189 ? 65.930 6.942 21.047 1.00 10.88 ? 191 GLY A CA 1 ATOM 1443 C C . GLY A 1 189 ? 66.119 5.669 20.239 1.00 10.29 ? 191 GLY A C 1 ATOM 1444 O O . GLY A 1 189 ? 65.538 4.633 20.557 1.00 10.36 ? 191 GLY A O 1 ATOM 1445 N N . VAL A 1 190 ? 66.894 5.754 19.161 1.00 10.00 ? 192 VAL A N 1 ATOM 1446 C CA . VAL A 1 190 ? 67.298 4.560 18.422 1.00 9.51 ? 192 VAL A CA 1 ATOM 1447 C C . VAL A 1 190 ? 68.302 3.731 19.231 1.00 9.37 ? 192 VAL A C 1 ATOM 1448 O O . VAL A 1 190 ? 68.299 2.495 19.174 1.00 8.96 ? 192 VAL A O 1 ATOM 1449 C CB . VAL A 1 190 ? 67.886 4.923 17.044 1.00 9.57 ? 192 VAL A CB 1 ATOM 1450 C CG1 . VAL A 1 190 ? 68.532 3.706 16.393 1.00 9.71 ? 192 VAL A CG1 1 ATOM 1451 C CG2 . VAL A 1 190 ? 66.804 5.499 16.141 1.00 9.47 ? 192 VAL A CG2 1 ATOM 1452 N N . ILE A 1 191 ? 69.107 4.419 20.036 1.00 8.57 ? 193 ILE A N 1 ATOM 1453 C CA . ILE A 1 191 ? 70.162 3.782 20.815 1.00 8.79 ? 193 ILE A CA 1 ATOM 1454 C C . ILE A 1 191 ? 69.816 3.728 22.304 1.00 8.94 ? 193 ILE A C 1 ATOM 1455 O O . ILE A 1 191 ? 70.054 2.719 22.968 1.00 9.01 ? 193 ILE A O 1 ATOM 1456 C CB . ILE A 1 191 ? 71.507 4.526 20.642 1.00 8.61 ? 193 ILE A CB 1 ATOM 1457 C CG1 . ILE A 1 191 ? 71.922 4.556 19.168 1.00 8.40 ? 193 ILE A CG1 1 ATOM 1458 C CG2 . ILE A 1 191 ? 72.588 3.883 21.497 1.00 8.85 ? 193 ILE A CG2 1 ATOM 1459 C CD1 . ILE A 1 191 ? 71.784 3.226 18.456 1.00 8.60 ? 193 ILE A CD1 1 ATOM 1460 N N . ILE A 1 192 ? 69.255 4.820 22.818 1.00 8.70 ? 194 ILE A N 1 ATOM 1461 C CA . ILE A 1 192 ? 69.029 4.979 24.255 1.00 8.98 ? 194 ILE A CA 1 ATOM 1462 C C . ILE A 1 192 ? 67.548 4.788 24.572 1.00 9.62 ? 194 ILE A C 1 ATOM 1463 O O . ILE A 1 192 ? 66.699 5.496 24.029 1.00 9.28 ? 194 ILE A O 1 ATOM 1464 C CB . ILE A 1 192 ? 69.462 6.383 24.741 1.00 9.01 ? 194 ILE A CB 1 ATOM 1465 C CG1 . ILE A 1 192 ? 70.944 6.631 24.441 1.00 9.23 ? 194 ILE A CG1 1 ATOM 1466 C CG2 . ILE A 1 192 ? 69.185 6.553 26.228 1.00 8.81 ? 194 ILE A CG2 1 ATOM 1467 C CD1 . ILE A 1 192 ? 71.877 5.663 25.139 1.00 8.98 ? 194 ILE A CD1 1 ATOM 1468 N N . THR A 1 193 ? 67.240 3.854 25.467 1.00 9.92 ? 195 THR A N 1 ATOM 1469 C CA . THR A 1 193 ? 65.849 3.580 25.820 1.00 10.68 ? 195 THR A CA 1 ATOM 1470 C C . THR A 1 193 ? 65.225 4.772 26.539 1.00 11.30 ? 195 THR A C 1 ATOM 1471 O O . THR A 1 193 ? 65.799 5.311 27.485 1.00 10.49 ? 195 THR A O 1 ATOM 1472 C CB . THR A 1 193 ? 65.704 2.320 26.697 1.00 10.82 ? 195 THR A CB 1 ATOM 1473 O OG1 . THR A 1 193 ? 66.623 2.384 27.795 1.00 10.34 ? 195 THR A OG1 1 ATOM 1474 C CG2 . THR A 1 193 ? 65.963 1.061 25.881 1.00 10.12 ? 195 THR A CG2 1 ATOM 1475 N N . GLY A 1 194 ? 64.061 5.199 26.062 1.00 11.87 ? 196 GLY A N 1 ATOM 1476 C CA . GLY A 1 194 ? 63.359 6.320 26.673 1.00 13.17 ? 196 GLY A CA 1 ATOM 1477 C C . GLY A 1 194 ? 63.835 7.655 26.136 1.00 13.36 ? 196 GLY A C 1 ATOM 1478 O O . GLY A 1 194 ? 63.336 8.705 26.539 1.00 13.26 ? 196 GLY A O 1 ATOM 1479 N N . ALA A 1 195 ? 64.812 7.617 25.234 1.00 13.81 ? 197 ALA A N 1 ATOM 1480 C CA . ALA A 1 195 ? 65.350 8.839 24.647 1.00 14.37 ? 197 ALA A CA 1 ATOM 1481 C C . ALA A 1 195 ? 64.498 9.306 23.474 1.00 13.75 ? 197 ALA A C 1 ATOM 1482 O O . ALA A 1 195 ? 63.491 8.687 23.143 1.00 13.19 ? 197 ALA A O 1 ATOM 1483 C CB . ALA A 1 195 ? 66.792 8.635 24.212 1.00 14.45 ? 197 ALA A CB 1 ATOM 1484 N N . THR A 1 196 ? 64.921 10.395 22.842 1.00 14.92 ? 198 THR A N 1 ATOM 1485 C CA . THR A 1 196 ? 64.116 11.061 21.820 1.00 16.25 ? 198 THR A CA 1 ATOM 1486 C C . THR A 1 196 ? 63.580 10.107 20.760 1.00 15.65 ? 198 THR A C 1 ATOM 1487 O O . THR A 1 196 ? 64.347 9.458 20.047 1.00 15.57 ? 198 THR A O 1 ATOM 1488 C CB . THR A 1 196 ? 64.911 12.181 21.127 1.00 16.69 ? 198 THR A CB 1 ATOM 1489 O OG1 . THR A 1 196 ? 65.392 13.101 22.111 1.00 17.89 ? 198 THR A OG1 1 ATOM 1490 C CG2 . THR A 1 196 ? 64.028 12.925 20.132 1.00 17.70 ? 198 THR A CG2 1 ATOM 1491 N N . ASN A 1 197 ? 62.256 10.049 20.650 1.00 16.04 ? 199 ASN A N 1 ATOM 1492 C CA . ASN A 1 197 ? 61.590 9.273 19.607 1.00 15.56 ? 199 ASN A CA 1 ATOM 1493 C C . ASN A 1 197 ? 61.779 7.761 19.713 1.00 14.51 ? 199 ASN A C 1 ATOM 1494 O O . ASN A 1 197 ? 61.584 7.038 18.739 1.00 14.23 ? 199 ASN A O 1 ATOM 1495 C CB . ASN A 1 197 ? 61.989 9.773 18.218 1.00 17.79 ? 199 ASN A CB 1 ATOM 1496 C CG . ASN A 1 197 ? 61.458 11.162 17.929 1.00 20.16 ? 199 ASN A CG 1 ATOM 1497 O OD1 . ASN A 1 197 ? 60.687 11.719 18.714 1.00 21.62 ? 199 ASN A OD1 1 ATOM 1498 N ND2 . ASN A 1 197 ? 61.869 11.731 16.804 1.00 20.46 ? 199 ASN A ND2 1 ATOM 1499 N N . ASP A 1 198 ? 62.124 7.284 20.906 1.00 12.90 ? 200 ASP A N 1 ATOM 1500 C CA . ASP A 1 198 ? 61.893 5.888 21.261 1.00 12.72 ? 200 ASP A CA 1 ATOM 1501 C C . ASP A 1 198 ? 60.405 5.699 21.534 1.00 12.66 ? 200 ASP A C 1 ATOM 1502 O O . ASP A 1 198 ? 59.864 6.312 22.452 1.00 13.10 ? 200 ASP A O 1 ATOM 1503 C CB . ASP A 1 198 ? 62.717 5.505 22.499 1.00 12.50 ? 200 ASP A CB 1 ATOM 1504 C CG . ASP A 1 198 ? 62.451 4.084 22.969 1.00 12.40 ? 200 ASP A CG 1 ATOM 1505 O OD1 . ASP A 1 198 ? 61.849 3.301 22.204 1.00 12.05 ? 200 ASP A OD1 1 ATOM 1506 O OD2 . ASP A 1 198 ? 62.843 3.748 24.110 1.00 11.89 ? 200 ASP A OD2 1 ATOM 1507 N N . PRO A 1 199 ? 59.726 4.901 20.693 1.00 12.81 ? 201 PRO A N 1 ATOM 1508 C CA . PRO A 1 199 ? 58.271 4.797 20.732 1.00 12.85 ? 201 PRO A CA 1 ATOM 1509 C C . PRO A 1 199 ? 57.781 3.812 21.789 1.00 12.86 ? 201 PRO A C 1 ATOM 1510 O O . PRO A 1 199 ? 56.586 3.772 22.087 1.00 11.66 ? 201 PRO A O 1 ATOM 1511 C CB . PRO A 1 199 ? 57.926 4.276 19.337 1.00 13.40 ? 201 PRO A CB 1 ATOM 1512 C CG . PRO A 1 199 ? 59.116 3.468 18.947 1.00 13.83 ? 201 PRO A CG 1 ATOM 1513 C CD . PRO A 1 199 ? 60.302 4.177 19.544 1.00 13.21 ? 201 PRO A CD 1 ATOM 1514 N N . ILE A 1 200 ? 58.697 3.017 22.335 1.00 12.20 ? 202 ILE A N 1 ATOM 1515 C CA . ILE A 1 200 ? 58.338 1.953 23.267 1.00 11.79 ? 202 ILE A CA 1 ATOM 1516 C C . ILE A 1 200 ? 58.323 2.461 24.708 1.00 11.99 ? 202 ILE A C 1 ATOM 1517 O O . ILE A 1 200 ? 59.301 3.042 25.181 1.00 11.37 ? 202 ILE A O 1 ATOM 1518 C CB . ILE A 1 200 ? 59.337 0.784 23.177 1.00 11.80 ? 202 ILE A CB 1 ATOM 1519 C CG1 . ILE A 1 200 ? 59.494 0.315 21.726 1.00 11.50 ? 202 ILE A CG1 1 ATOM 1520 C CG2 . ILE A 1 200 ? 58.929 -0.348 24.110 1.00 12.33 ? 202 ILE A CG2 1 ATOM 1521 C CD1 . ILE A 1 200 ? 58.188 0.154 20.973 1.00 11.72 ? 202 ILE A CD1 1 ATOM 1522 N N . THR A 1 201 ? 57.225 2.217 25.416 1.00 11.83 ? 203 THR A N 1 ATOM 1523 C CA . THR A 1 201 ? 57.147 2.584 26.824 1.00 11.04 ? 203 THR A CA 1 ATOM 1524 C C . THR A 1 201 ? 58.159 1.787 27.642 1.00 11.32 ? 203 THR A C 1 ATOM 1525 O O . THR A 1 201 ? 58.249 0.565 27.507 1.00 10.93 ? 203 THR A O 1 ATOM 1526 C CB . THR A 1 201 ? 55.740 2.337 27.394 1.00 11.03 ? 203 THR A CB 1 ATOM 1527 O OG1 . THR A 1 201 ? 54.791 3.165 26.712 1.00 11.03 ? 203 THR A OG1 1 ATOM 1528 C CG2 . THR A 1 201 ? 55.707 2.650 28.890 1.00 11.08 ? 203 THR A CG2 1 ATOM 1529 N N . ARG A 1 202 ? 58.922 2.488 28.481 1.00 10.52 ? 204 ARG A N 1 ATOM 1530 C CA . ARG A 1 202 ? 59.874 1.848 29.390 1.00 10.08 ? 204 ARG A CA 1 ATOM 1531 C C . ARG A 1 202 ? 59.530 2.157 30.845 1.00 10.08 ? 204 ARG A C 1 ATOM 1532 O O . ARG A 1 202 ? 58.871 3.154 31.126 1.00 10.20 ? 204 ARG A O 1 ATOM 1533 C CB . ARG A 1 202 ? 61.293 2.340 29.101 1.00 9.97 ? 204 ARG A CB 1 ATOM 1534 C CG . ARG A 1 202 ? 61.604 2.504 27.621 1.00 10.05 ? 204 ARG A CG 1 ATOM 1535 C CD . ARG A 1 202 ? 61.908 1.166 26.967 1.00 10.20 ? 204 ARG A CD 1 ATOM 1536 N NE . ARG A 1 202 ? 62.256 1.327 25.555 1.00 9.95 ? 204 ARG A NE 1 ATOM 1537 C CZ . ARG A 1 202 ? 62.503 0.319 24.724 1.00 10.31 ? 204 ARG A CZ 1 ATOM 1538 N NH1 . ARG A 1 202 ? 62.437 -0.934 25.155 1.00 10.07 ? 204 ARG A NH1 1 ATOM 1539 N NH2 . ARG A 1 202 ? 62.792 0.565 23.452 1.00 10.31 ? 204 ARG A NH2 1 ATOM 1540 N N . PRO A 1 203 ? 60.008 1.320 31.780 1.00 9.89 ? 205 PRO A N 1 ATOM 1541 C CA . PRO A 1 203 ? 60.015 1.729 33.183 1.00 10.14 ? 205 PRO A CA 1 ATOM 1542 C C . PRO A 1 203 ? 60.823 3.010 33.344 1.00 10.06 ? 205 PRO A C 1 ATOM 1543 O O . PRO A 1 203 ? 61.838 3.182 32.677 1.00 9.48 ? 205 PRO A O 1 ATOM 1544 C CB . PRO A 1 203 ? 60.732 0.572 33.889 1.00 10.02 ? 205 PRO A CB 1 ATOM 1545 C CG . PRO A 1 203 ? 60.623 -0.588 32.956 1.00 10.32 ? 205 PRO A CG 1 ATOM 1546 C CD . PRO A 1 203 ? 60.628 0.001 31.576 1.00 10.40 ? 205 PRO A CD 1 ATOM 1547 N N . SER A 1 204 ? 60.375 3.904 34.220 1.00 10.56 ? 206 SER A N 1 ATOM 1548 C CA . SER A 1 204 ? 61.056 5.183 34.402 1.00 11.01 ? 206 SER A CA 1 ATOM 1549 C C . SER A 1 204 ? 62.547 5.028 34.726 1.00 11.46 ? 206 SER A C 1 ATOM 1550 O O . SER A 1 204 ? 63.375 5.813 34.253 1.00 11.21 ? 206 SER A O 1 ATOM 1551 C CB . SER A 1 204 ? 60.358 6.018 35.478 1.00 11.20 ? 206 SER A CB 1 ATOM 1552 O OG . SER A 1 204 ? 60.283 5.306 36.700 1.00 11.59 ? 206 SER A OG 1 ATOM 1553 N N . TRP A 1 205 ? 62.888 4.015 35.520 1.00 11.11 ? 207 TRP A N 1 ATOM 1554 C CA . TRP A 1 205 ? 64.279 3.809 35.949 1.00 11.31 ? 207 TRP A CA 1 ATOM 1555 C C . TRP A 1 205 ? 65.190 3.357 34.808 1.00 11.34 ? 207 TRP A C 1 ATOM 1556 O O . TRP A 1 205 ? 66.416 3.410 34.924 1.00 11.29 ? 207 TRP A O 1 ATOM 1557 C CB . TRP A 1 205 ? 64.354 2.805 37.105 1.00 11.34 ? 207 TRP A CB 1 ATOM 1558 C CG . TRP A 1 205 ? 63.788 1.459 36.770 1.00 11.21 ? 207 TRP A CG 1 ATOM 1559 C CD1 . TRP A 1 205 ? 62.530 1.002 37.049 1.00 11.05 ? 207 TRP A CD1 1 ATOM 1560 C CD2 . TRP A 1 205 ? 64.460 0.391 36.089 1.00 11.61 ? 207 TRP A CD2 1 ATOM 1561 N NE1 . TRP A 1 205 ? 62.376 -0.277 36.573 1.00 10.92 ? 207 TRP A NE1 1 ATOM 1562 C CE2 . TRP A 1 205 ? 63.543 -0.674 35.977 1.00 11.65 ? 207 TRP A CE2 1 ATOM 1563 C CE3 . TRP A 1 205 ? 65.742 0.237 35.553 1.00 11.50 ? 207 TRP A CE3 1 ATOM 1564 C CZ2 . TRP A 1 205 ? 63.873 -1.883 35.365 1.00 12.00 ? 207 TRP A CZ2 1 ATOM 1565 C CZ3 . TRP A 1 205 ? 66.067 -0.960 34.941 1.00 11.86 ? 207 TRP A CZ3 1 ATOM 1566 C CH2 . TRP A 1 205 ? 65.134 -2.002 34.847 1.00 11.97 ? 207 TRP A CH2 1 ATOM 1567 N N . ALA A 1 206 ? 64.589 2.916 33.707 1.00 10.98 ? 208 ALA A N 1 ATOM 1568 C CA . ALA A 1 206 ? 65.352 2.387 32.582 1.00 11.18 ? 208 ALA A CA 1 ATOM 1569 C C . ALA A 1 206 ? 65.620 3.436 31.498 1.00 10.61 ? 208 ALA A C 1 ATOM 1570 O O . ALA A 1 206 ? 66.278 3.151 30.496 1.00 10.91 ? 208 ALA A O 1 ATOM 1571 C CB . ALA A 1 206 ? 64.651 1.171 31.990 1.00 10.86 ? 208 ALA A CB 1 ATOM 1572 N N . VAL A 1 207 ? 65.122 4.651 31.706 1.00 10.59 ? 209 VAL A N 1 ATOM 1573 C CA . VAL A 1 207 ? 65.369 5.745 30.772 1.00 10.55 ? 209 VAL A CA 1 ATOM 1574 C C . VAL A 1 207 ? 66.829 6.195 30.838 1.00 10.64 ? 209 VAL A C 1 ATOM 1575 O O . VAL A 1 207 ? 67.314 6.604 31.892 1.00 11.57 ? 209 VAL A O 1 ATOM 1576 C CB . VAL A 1 207 ? 64.448 6.950 31.053 1.00 11.01 ? 209 VAL A CB 1 ATOM 1577 C CG1 . VAL A 1 207 ? 64.812 8.123 30.153 1.00 11.54 ? 209 VAL A CG1 1 ATOM 1578 C CG2 . VAL A 1 207 ? 62.991 6.554 30.863 1.00 10.92 ? 209 VAL A CG2 1 ATOM 1579 N N . GLY A 1 208 ? 67.522 6.108 29.706 1.00 9.96 ? 210 GLY A N 1 ATOM 1580 C CA . GLY A 1 208 ? 68.957 6.371 29.661 1.00 9.80 ? 210 GLY A CA 1 ATOM 1581 C C . GLY A 1 208 ? 69.793 5.111 29.496 1.00 9.48 ? 210 GLY A C 1 ATOM 1582 O O . GLY A 1 208 ? 71.022 5.178 29.427 1.00 9.40 ? 210 GLY A O 1 ATOM 1583 N N . GLY A 1 209 ? 69.129 3.959 29.450 1.00 9.22 ? 211 GLY A N 1 ATOM 1584 C CA . GLY A 1 209 ? 69.816 2.679 29.258 1.00 8.77 ? 211 GLY A CA 1 ATOM 1585 C C . GLY A 1 209 ? 69.925 2.258 27.801 1.00 9.11 ? 211 GLY A C 1 ATOM 1586 O O . GLY A 1 209 ? 69.603 3.025 26.893 1.00 8.83 ? 211 GLY A O 1 ATOM 1587 N N . SER A 1 210 ? 70.411 1.041 27.575 1.00 8.77 ? 212 SER A N 1 ATOM 1588 C CA . SER A 1 210 ? 70.484 0.479 26.233 1.00 8.74 ? 212 SER A CA 1 ATOM 1589 C C . SER A 1 210 ? 70.538 -1.045 26.322 1.00 8.56 ? 212 SER A C 1 ATOM 1590 O O . SER A 1 210 ? 71.012 -1.598 27.311 1.00 8.39 ? 212 SER A O 1 ATOM 1591 C CB . SER A 1 210 ? 71.720 1.012 25.503 1.00 8.88 ? 212 SER A CB 1 ATOM 1592 O OG . SER A 1 210 ? 71.657 0.742 24.112 1.00 9.44 ? 212 SER A OG 1 ATOM 1593 N N . PHE A 1 211 ? 70.023 -1.723 25.304 1.00 8.68 ? 213 PHE A N 1 ATOM 1594 C CA . PHE A 1 211 ? 70.190 -3.166 25.217 1.00 9.02 ? 213 PHE A CA 1 ATOM 1595 C C . PHE A 1 211 ? 71.531 -3.534 24.601 1.00 9.00 ? 213 PHE A C 1 ATOM 1596 O O . PHE A 1 211 ? 71.891 -3.060 23.521 1.00 9.77 ? 213 PHE A O 1 ATOM 1597 C CB . PHE A 1 211 ? 69.035 -3.818 24.457 1.00 9.03 ? 213 PHE A CB 1 ATOM 1598 C CG . PHE A 1 211 ? 67.720 -3.731 25.179 1.00 9.82 ? 213 PHE A CG 1 ATOM 1599 C CD1 . PHE A 1 211 ? 67.469 -4.527 26.284 1.00 10.26 ? 213 PHE A CD1 1 ATOM 1600 C CD2 . PHE A 1 211 ? 66.769 -2.802 24.799 1.00 10.03 ? 213 PHE A CD2 1 ATOM 1601 C CE1 . PHE A 1 211 ? 66.277 -4.422 26.977 1.00 10.76 ? 213 PHE A CE1 1 ATOM 1602 C CE2 . PHE A 1 211 ? 65.571 -2.696 25.482 1.00 10.60 ? 213 PHE A CE2 1 ATOM 1603 C CZ . PHE A 1 211 ? 65.329 -3.502 26.578 1.00 10.85 ? 213 PHE A CZ 1 ATOM 1604 N N . LEU A 1 212 ? 72.257 -4.388 25.309 1.00 9.04 ? 214 LEU A N 1 ATOM 1605 C CA . LEU A 1 212 ? 73.579 -4.835 24.910 1.00 8.98 ? 214 LEU A CA 1 ATOM 1606 C C . LEU A 1 212 ? 73.459 -6.247 24.347 1.00 8.66 ? 214 LEU A C 1 ATOM 1607 O O . LEU A 1 212 ? 73.070 -7.170 25.058 1.00 9.28 ? 214 LEU A O 1 ATOM 1608 C CB . LEU A 1 212 ? 74.499 -4.836 26.135 1.00 8.75 ? 214 LEU A CB 1 ATOM 1609 C CG . LEU A 1 212 ? 76.008 -5.039 25.965 1.00 8.81 ? 214 LEU A CG 1 ATOM 1610 C CD1 . LEU A 1 212 ? 76.690 -4.941 27.322 1.00 9.09 ? 214 LEU A CD1 1 ATOM 1611 C CD2 . LEU A 1 212 ? 76.320 -6.372 25.300 1.00 8.75 ? 214 LEU A CD2 1 ATOM 1612 N N . ALA A 1 213 ? 73.683 -6.392 23.044 1.00 8.68 ? 215 ALA A N 1 ATOM 1613 C CA . ALA A 1 213 ? 73.723 -7.712 22.429 1.00 8.58 ? 215 ALA A CA 1 ATOM 1614 C C . ALA A 1 213 ? 75.164 -8.201 22.371 1.00 8.66 ? 215 ALA A C 1 ATOM 1615 O O . ALA A 1 213 ? 75.988 -7.649 21.637 1.00 8.84 ? 215 ALA A O 1 ATOM 1616 C CB . ALA A 1 213 ? 73.110 -7.677 21.033 1.00 8.42 ? 215 ALA A CB 1 ATOM 1617 N N . PHE A 1 214 ? 75.475 -9.196 23.194 1.00 8.60 ? 216 PHE A N 1 ATOM 1618 C CA . PHE A 1 214 ? 76.811 -9.775 23.223 1.00 8.73 ? 216 PHE A CA 1 ATOM 1619 C C . PHE A 1 214 ? 76.863 -11.050 22.390 1.00 8.68 ? 216 PHE A C 1 ATOM 1620 O O . PHE A 1 214 ? 75.986 -11.910 22.504 1.00 8.53 ? 216 PHE A O 1 ATOM 1621 C CB . PHE A 1 214 ? 77.247 -10.070 24.661 1.00 8.76 ? 216 PHE A CB 1 ATOM 1622 C CG . PHE A 1 214 ? 78.632 -10.642 24.761 1.00 8.81 ? 216 PHE A CG 1 ATOM 1623 C CD1 . PHE A 1 214 ? 78.843 -12.005 24.624 1.00 8.85 ? 216 PHE A CD1 1 ATOM 1624 C CD2 . PHE A 1 214 ? 79.732 -9.808 24.898 1.00 8.68 ? 216 PHE A CD2 1 ATOM 1625 C CE1 . PHE A 1 214 ? 80.120 -12.532 24.670 1.00 8.81 ? 216 PHE A CE1 1 ATOM 1626 C CE2 . PHE A 1 214 ? 81.012 -10.330 24.949 1.00 8.84 ? 216 PHE A CE2 1 ATOM 1627 C CZ . PHE A 1 214 ? 81.207 -11.693 24.820 1.00 9.08 ? 216 PHE A CZ 1 ATOM 1628 N N . ARG A 1 215 ? 77.894 -11.162 21.557 1.00 8.66 ? 217 ARG A N 1 ATOM 1629 C CA . ARG A 1 215 ? 78.123 -12.352 20.746 1.00 8.76 ? 217 ARG A CA 1 ATOM 1630 C C . ARG A 1 215 ? 79.601 -12.740 20.772 1.00 9.16 ? 217 ARG A C 1 ATOM 1631 O O . ARG A 1 215 ? 80.473 -11.932 20.438 1.00 8.78 ? 217 ARG A O 1 ATOM 1632 C CB . ARG A 1 215 ? 77.687 -12.114 19.294 1.00 8.58 ? 217 ARG A CB 1 ATOM 1633 C CG . ARG A 1 215 ? 76.214 -11.775 19.122 1.00 9.01 ? 217 ARG A CG 1 ATOM 1634 C CD . ARG A 1 215 ? 75.365 -13.030 18.998 1.00 8.72 ? 217 ARG A CD 1 ATOM 1635 N NE . ARG A 1 215 ? 75.402 -13.586 17.646 1.00 8.91 ? 217 ARG A NE 1 ATOM 1636 C CZ . ARG A 1 215 ? 74.922 -14.781 17.318 1.00 9.43 ? 217 ARG A CZ 1 ATOM 1637 N NH1 . ARG A 1 215 ? 74.408 -15.568 18.253 1.00 9.02 ? 217 ARG A NH1 1 ATOM 1638 N NH2 . ARG A 1 215 ? 74.983 -15.204 16.060 1.00 9.75 ? 217 ARG A NH2 1 ATOM 1639 N N . GLN A 1 216 ? 79.880 -13.983 21.154 1.00 8.64 ? 218 GLN A N 1 ATOM 1640 C CA . GLN A 1 216 ? 81.230 -14.513 21.035 1.00 8.80 ? 218 GLN A CA 1 ATOM 1641 C C . GLN A 1 216 ? 81.389 -15.133 19.656 1.00 8.89 ? 218 GLN A C 1 ATOM 1642 O O . GLN A 1 216 ? 80.892 -16.231 19.401 1.00 8.65 ? 218 GLN A O 1 ATOM 1643 C CB . GLN A 1 216 ? 81.502 -15.560 22.115 1.00 9.25 ? 218 GLN A CB 1 ATOM 1644 C CG . GLN A 1 216 ? 82.922 -16.116 22.087 1.00 9.50 ? 218 GLN A CG 1 ATOM 1645 C CD . GLN A 1 216 ? 83.228 -16.993 23.288 1.00 10.91 ? 218 GLN A CD 1 ATOM 1646 O OE1 . GLN A 1 216 ? 82.798 -16.707 24.408 1.00 11.11 ? 218 GLN A OE1 1 ATOM 1647 N NE2 . GLN A 1 216 ? 83.996 -18.055 23.065 1.00 11.80 ? 218 GLN A NE2 1 ATOM 1648 N N . LEU A 1 217 ? 82.033 -14.400 18.755 1.00 8.31 ? 219 LEU A N 1 ATOM 1649 C CA . LEU A 1 217 ? 82.128 -14.818 17.364 1.00 8.38 ? 219 LEU A CA 1 ATOM 1650 C C . LEU A 1 217 ? 83.544 -15.270 17.022 1.00 8.71 ? 219 LEU A C 1 ATOM 1651 O O . LEU A 1 217 ? 84.430 -14.443 16.808 1.00 8.43 ? 219 LEU A O 1 ATOM 1652 C CB . LEU A 1 217 ? 81.701 -13.674 16.440 1.00 8.00 ? 219 LEU A CB 1 ATOM 1653 C CG . LEU A 1 217 ? 80.267 -13.177 16.652 1.00 8.15 ? 219 LEU A CG 1 ATOM 1654 C CD1 . LEU A 1 217 ? 79.930 -12.047 15.691 1.00 8.38 ? 219 LEU A CD1 1 ATOM 1655 C CD2 . LEU A 1 217 ? 79.272 -14.320 16.517 1.00 8.00 ? 219 LEU A CD2 1 ATOM 1656 N N . GLU A 1 218 ? 83.755 -16.583 16.971 1.00 9.18 ? 220 GLU A N 1 ATOM 1657 C CA . GLU A 1 218 ? 85.061 -17.116 16.611 1.00 9.86 ? 220 GLU A CA 1 ATOM 1658 C C . GLU A 1 218 ? 85.348 -16.828 15.147 1.00 9.90 ? 220 GLU A C 1 ATOM 1659 O O . GLU A 1 218 ? 84.466 -16.952 14.300 1.00 10.15 ? 220 GLU A O 1 ATOM 1660 C CB . GLU A 1 218 ? 85.141 -18.624 16.862 1.00 11.28 ? 220 GLU A CB 1 ATOM 1661 C CG . GLU A 1 218 ? 86.378 -19.258 16.236 1.00 11.64 ? 220 GLU A CG 1 ATOM 1662 C CD . GLU A 1 218 ? 86.604 -20.693 16.667 1.00 13.36 ? 220 GLU A CD 1 ATOM 1663 O OE1 . GLU A 1 218 ? 85.621 -21.371 17.036 1.00 13.65 ? 220 GLU A OE1 1 ATOM 1664 O OE2 . GLU A 1 218 ? 87.764 -21.155 16.594 1.00 13.49 ? 220 GLU A OE2 1 ATOM 1665 N N . GLN A 1 219 ? 86.573 -16.405 14.860 1.00 9.60 ? 221 GLN A N 1 ATOM 1666 C CA . GLN A 1 219 ? 86.986 -16.167 13.485 1.00 9.36 ? 221 GLN A CA 1 ATOM 1667 C C . GLN A 1 219 ? 88.043 -17.178 13.066 1.00 9.38 ? 221 GLN A C 1 ATOM 1668 O O . GLN A 1 219 ? 89.017 -17.396 13.781 1.00 9.70 ? 221 GLN A O 1 ATOM 1669 C CB . GLN A 1 219 ? 87.515 -14.744 13.330 1.00 9.62 ? 221 GLN A CB 1 ATOM 1670 C CG . GLN A 1 219 ? 86.446 -13.679 13.511 1.00 9.67 ? 221 GLN A CG 1 ATOM 1671 C CD . GLN A 1 219 ? 87.020 -12.278 13.564 1.00 10.47 ? 221 GLN A CD 1 ATOM 1672 O OE1 . GLN A 1 219 ? 87.105 -11.669 14.631 1.00 10.67 ? 221 GLN A OE1 1 ATOM 1673 N NE2 . GLN A 1 219 ? 87.417 -11.760 12.410 1.00 10.67 ? 221 GLN A NE2 1 ATOM 1674 N N . LEU A 1 220 ? 87.829 -17.815 11.919 1.00 9.31 ? 222 LEU A N 1 ATOM 1675 C CA . LEU A 1 220 ? 88.768 -18.801 11.404 1.00 9.26 ? 222 LEU A CA 1 ATOM 1676 C C . LEU A 1 220 ? 89.711 -18.147 10.403 1.00 8.93 ? 222 LEU A C 1 ATOM 1677 O O . LEU A 1 220 ? 89.468 -18.172 9.198 1.00 8.65 ? 222 LEU A O 1 ATOM 1678 C CB . LEU A 1 220 ? 88.019 -19.961 10.746 1.00 9.27 ? 222 LEU A CB 1 ATOM 1679 C CG . LEU A 1 220 ? 86.971 -20.654 11.619 1.00 9.70 ? 222 LEU A CG 1 ATOM 1680 C CD1 . LEU A 1 220 ? 86.199 -21.677 10.795 1.00 9.37 ? 222 LEU A CD1 1 ATOM 1681 C CD2 . LEU A 1 220 ? 87.636 -21.318 12.818 1.00 9.47 ? 222 LEU A CD2 1 ATOM 1682 N N . VAL A 1 221 ? 90.771 -17.540 10.922 1.00 8.60 ? 223 VAL A N 1 ATOM 1683 C CA . VAL A 1 221 ? 91.577 -16.603 10.152 1.00 8.96 ? 223 VAL A CA 1 ATOM 1684 C C . VAL A 1 221 ? 92.418 -17.300 9.081 1.00 9.13 ? 223 VAL A C 1 ATOM 1685 O O . VAL A 1 221 ? 92.406 -16.895 7.915 1.00 9.40 ? 223 VAL A O 1 ATOM 1686 C CB . VAL A 1 221 ? 92.457 -15.733 11.074 1.00 8.59 ? 223 VAL A CB 1 ATOM 1687 C CG1 . VAL A 1 221 ? 93.309 -14.770 10.256 1.00 8.25 ? 223 VAL A CG1 1 ATOM 1688 C CG2 . VAL A 1 221 ? 91.579 -14.970 12.057 1.00 8.61 ? 223 VAL A CG2 1 ATOM 1689 N N . PRO A 1 222 ? 93.126 -18.375 9.461 1.00 9.29 ? 224 PRO A N 1 ATOM 1690 C CA . PRO A 1 222 ? 93.914 -19.100 8.463 1.00 9.56 ? 224 PRO A CA 1 ATOM 1691 C C . PRO A 1 222 ? 93.038 -19.665 7.347 1.00 9.66 ? 224 PRO A C 1 ATOM 1692 O O . PRO A 1 222 ? 93.436 -19.656 6.181 1.00 9.60 ? 224 PRO A O 1 ATOM 1693 C CB . PRO A 1 222 ? 94.541 -20.237 9.275 1.00 9.89 ? 224 PRO A CB 1 ATOM 1694 C CG . PRO A 1 222 ? 94.616 -19.698 10.666 1.00 9.55 ? 224 PRO A CG 1 ATOM 1695 C CD . PRO A 1 222 ? 93.375 -18.866 10.828 1.00 9.30 ? 224 PRO A CD 1 ATOM 1696 N N . GLU A 1 223 ? 91.839 -20.117 7.703 1.00 10.05 ? 225 GLU A N 1 ATOM 1697 C CA . GLU A 1 223 ? 90.895 -20.651 6.726 1.00 10.63 ? 225 GLU A CA 1 ATOM 1698 C C . GLU A 1 223 ? 90.369 -19.553 5.791 1.00 10.44 ? 225 GLU A C 1 ATOM 1699 O O . GLU A 1 223 ? 90.275 -19.746 4.579 1.00 11.03 ? 225 GLU A O 1 ATOM 1700 C CB . GLU A 1 223 ? 89.737 -21.362 7.437 1.00 10.49 ? 225 GLU A CB 1 ATOM 1701 C CG . GLU A 1 223 ? 90.134 -22.656 8.139 1.00 10.70 ? 225 GLU A CG 1 ATOM 1702 C CD . GLU A 1 223 ? 90.593 -22.452 9.577 1.00 11.10 ? 225 GLU A CD 1 ATOM 1703 O OE1 . GLU A 1 223 ? 91.003 -21.324 9.942 1.00 11.15 ? 225 GLU A OE1 1 ATOM 1704 O OE2 . GLU A 1 223 ? 90.581 -23.439 10.343 1.00 11.23 ? 225 GLU A OE2 1 ATOM 1705 N N . PHE A 1 224 ? 90.061 -18.393 6.363 1.00 10.43 ? 226 PHE A N 1 ATOM 1706 C CA . PHE A 1 224 ? 89.682 -17.211 5.593 1.00 10.35 ? 226 PHE A CA 1 ATOM 1707 C C . PHE A 1 224 ? 90.766 -16.856 4.577 1.00 10.71 ? 226 PHE A C 1 ATOM 1708 O O . PHE A 1 224 ? 90.494 -16.704 3.381 1.00 10.04 ? 226 PHE A O 1 ATOM 1709 C CB . PHE A 1 224 ? 89.442 -16.041 6.554 1.00 10.43 ? 226 PHE A CB 1 ATOM 1710 C CG . PHE A 1 224 ? 89.126 -14.733 5.879 1.00 10.51 ? 226 PHE A CG 1 ATOM 1711 C CD1 . PHE A 1 224 ? 87.861 -14.485 5.376 1.00 11.31 ? 226 PHE A CD1 1 ATOM 1712 C CD2 . PHE A 1 224 ? 90.058 -13.706 5.867 1.00 10.76 ? 226 PHE A CD2 1 ATOM 1713 C CE1 . PHE A 1 224 ? 87.545 -13.256 4.824 1.00 11.42 ? 226 PHE A CE1 1 ATOM 1714 C CE2 . PHE A 1 224 ? 89.757 -12.479 5.302 1.00 11.25 ? 226 PHE A CE2 1 ATOM 1715 C CZ . PHE A 1 224 ? 88.494 -12.250 4.786 1.00 11.26 ? 226 PHE A CZ 1 ATOM 1716 N N . ASN A 1 225 ? 92.004 -16.767 5.050 1.00 10.36 ? 227 ASN A N 1 ATOM 1717 C CA . ASN A 1 225 ? 93.107 -16.359 4.195 1.00 9.80 ? 227 ASN A CA 1 ATOM 1718 C C . ASN A 1 225 ? 93.378 -17.359 3.076 1.00 9.52 ? 227 ASN A C 1 ATOM 1719 O O . ASN A 1 225 ? 93.645 -16.971 1.941 1.00 8.54 ? 227 ASN A O 1 ATOM 1720 C CB . ASN A 1 225 ? 94.365 -16.101 5.027 1.00 9.83 ? 227 ASN A CB 1 ATOM 1721 C CG . ASN A 1 225 ? 94.269 -14.819 5.833 1.00 10.23 ? 227 ASN A CG 1 ATOM 1722 O OD1 . ASN A 1 225 ? 93.584 -13.878 5.433 1.00 11.17 ? 227 ASN A OD1 1 ATOM 1723 N ND2 . ASN A 1 225 ? 94.935 -14.784 6.982 1.00 10.20 ? 227 ASN A ND2 1 ATOM 1724 N N . LYS A 1 226 ? 93.269 -18.645 3.390 1.00 9.89 ? 228 LYS A N 1 ATOM 1725 C CA . LYS A 1 226 ? 93.399 -19.688 2.378 1.00 10.41 ? 228 LYS A CA 1 ATOM 1726 C C . LYS A 1 226 ? 92.306 -19.582 1.316 1.00 10.21 ? 228 LYS A C 1 ATOM 1727 O O . LYS A 1 226 ? 92.583 -19.685 0.117 1.00 9.88 ? 228 LYS A O 1 ATOM 1728 C CB . LYS A 1 226 ? 93.384 -21.074 3.025 1.00 11.17 ? 228 LYS A CB 1 ATOM 1729 C CG . LYS A 1 226 ? 93.463 -22.226 2.032 1.00 12.77 ? 228 LYS A CG 1 ATOM 1730 C CD . LYS A 1 226 ? 93.340 -23.570 2.733 1.00 13.55 ? 228 LYS A CD 1 ATOM 1731 C CE . LYS A 1 226 ? 93.083 -24.692 1.739 1.00 15.22 ? 228 LYS A CE 1 ATOM 1732 N NZ . LYS A 1 226 ? 94.253 -24.900 0.842 1.00 16.06 ? 228 LYS A NZ 1 ATOM 1733 N N . TYR A 1 227 ? 91.068 -19.364 1.753 1.00 10.27 ? 229 TYR A N 1 ATOM 1734 C CA . TYR A 1 227 ? 89.953 -19.236 0.820 1.00 10.84 ? 229 TYR A CA 1 ATOM 1735 C C . TYR A 1 227 ? 90.173 -18.091 -0.161 1.00 11.01 ? 229 TYR A C 1 ATOM 1736 O O . TYR A 1 227 ? 89.917 -18.227 -1.360 1.00 11.14 ? 229 TYR A O 1 ATOM 1737 C CB . TYR A 1 227 ? 88.622 -19.051 1.556 1.00 11.46 ? 229 TYR A CB 1 ATOM 1738 C CG . TYR A 1 227 ? 87.428 -19.086 0.631 1.00 12.19 ? 229 TYR A CG 1 ATOM 1739 C CD1 . TYR A 1 227 ? 87.032 -17.949 -0.067 1.00 11.53 ? 229 TYR A CD1 1 ATOM 1740 C CD2 . TYR A 1 227 ? 86.727 -20.268 0.413 1.00 12.20 ? 229 TYR A CD2 1 ATOM 1741 C CE1 . TYR A 1 227 ? 85.969 -17.986 -0.949 1.00 11.69 ? 229 TYR A CE1 1 ATOM 1742 C CE2 . TYR A 1 227 ? 85.661 -20.314 -0.466 1.00 12.27 ? 229 TYR A CE2 1 ATOM 1743 C CZ . TYR A 1 227 ? 85.284 -19.170 -1.139 1.00 12.15 ? 229 TYR A CZ 1 ATOM 1744 O OH . TYR A 1 227 ? 84.247 -19.216 -2.040 1.00 12.64 ? 229 TYR A OH 1 ATOM 1745 N N . LEU A 1 228 ? 90.650 -16.962 0.350 1.00 11.21 ? 230 LEU A N 1 ATOM 1746 C CA . LEU A 1 228 ? 90.953 -15.817 -0.504 1.00 11.29 ? 230 LEU A CA 1 ATOM 1747 C C . LEU A 1 228 ? 92.011 -16.144 -1.557 1.00 11.68 ? 230 LEU A C 1 ATOM 1748 O O . LEU A 1 228 ? 91.863 -15.785 -2.731 1.00 12.50 ? 230 LEU A O 1 ATOM 1749 C CB . LEU A 1 228 ? 91.375 -14.609 0.335 1.00 10.62 ? 230 LEU A CB 1 ATOM 1750 C CG . LEU A 1 228 ? 90.332 -14.089 1.329 1.00 10.70 ? 230 LEU A CG 1 ATOM 1751 C CD1 . LEU A 1 228 ? 90.843 -12.849 2.045 1.00 10.95 ? 230 LEU A CD1 1 ATOM 1752 C CD2 . LEU A 1 228 ? 89.009 -13.798 0.635 1.00 10.71 ? 230 LEU A CD2 1 ATOM 1753 N N . LEU A 1 229 ? 93.066 -16.842 -1.143 1.00 12.12 ? 231 LEU A N 1 ATOM 1754 C CA . LEU A 1 229 ? 94.111 -17.266 -2.071 1.00 12.52 ? 231 LEU A CA 1 ATOM 1755 C C . LEU A 1 229 ? 93.549 -18.197 -3.141 1.00 12.87 ? 231 LEU A C 1 ATOM 1756 O O . LEU A 1 229 ? 93.848 -18.050 -4.327 1.00 12.99 ? 231 LEU A O 1 ATOM 1757 C CB . LEU A 1 229 ? 95.244 -17.980 -1.324 1.00 13.20 ? 231 LEU A CB 1 ATOM 1758 C CG . LEU A 1 229 ? 96.330 -17.134 -0.654 1.00 14.19 ? 231 LEU A CG 1 ATOM 1759 C CD1 . LEU A 1 229 ? 97.415 -18.038 -0.084 1.00 14.69 ? 231 LEU A CD1 1 ATOM 1760 C CD2 . LEU A 1 229 ? 96.931 -16.136 -1.633 1.00 13.53 ? 231 LEU A CD2 1 ATOM 1761 N N . ASP A 1 230 ? 92.757 -19.174 -2.711 1.00 13.00 ? 232 ASP A N 1 ATOM 1762 C CA . ASP A 1 230 ? 92.288 -20.229 -3.606 1.00 14.32 ? 232 ASP A CA 1 ATOM 1763 C C . ASP A 1 230 ? 91.210 -19.740 -4.568 1.00 14.18 ? 232 ASP A C 1 ATOM 1764 O O . ASP A 1 230 ? 91.045 -20.289 -5.656 1.00 14.67 ? 232 ASP A O 1 ATOM 1765 C CB . ASP A 1 230 ? 91.769 -21.420 -2.805 1.00 14.61 ? 232 ASP A CB 1 ATOM 1766 C CG . ASP A 1 230 ? 92.881 -22.191 -2.128 1.00 15.64 ? 232 ASP A CG 1 ATOM 1767 O OD1 . ASP A 1 230 ? 94.062 -21.926 -2.432 1.00 15.99 ? 232 ASP A OD1 1 ATOM 1768 O OD2 . ASP A 1 230 ? 92.575 -23.055 -1.283 1.00 17.21 ? 232 ASP A OD2 1 ATOM 1769 N N . ASN A 1 231 ? 90.494 -18.692 -4.176 1.00 12.91 ? 233 ASN A N 1 ATOM 1770 C CA . ASN A 1 231 ? 89.361 -18.219 -4.957 1.00 12.73 ? 233 ASN A CA 1 ATOM 1771 C C . ASN A 1 231 ? 89.564 -16.821 -5.531 1.00 12.77 ? 233 ASN A C 1 ATOM 1772 O O . ASN A 1 231 ? 88.657 -16.259 -6.143 1.00 13.91 ? 233 ASN A O 1 ATOM 1773 C CB . ASN A 1 231 ? 88.081 -18.277 -4.123 1.00 12.31 ? 233 ASN A CB 1 ATOM 1774 C CG . ASN A 1 231 ? 87.659 -19.697 -3.810 1.00 12.85 ? 233 ASN A CG 1 ATOM 1775 O OD1 . ASN A 1 231 ? 87.019 -20.359 -4.627 1.00 13.08 ? 233 ASN A OD1 1 ATOM 1776 N ND2 . ASN A 1 231 ? 88.062 -20.193 -2.645 1.00 12.11 ? 233 ASN A ND2 1 ATOM 1777 N N . ALA A 1 232 ? 90.755 -16.266 -5.330 1.00 12.98 ? 234 ALA A N 1 ATOM 1778 C CA . ALA A 1 232 ? 91.113 -14.981 -5.922 1.00 13.04 ? 234 ALA A CA 1 ATOM 1779 C C . ALA A 1 232 ? 90.750 -14.970 -7.403 1.00 13.70 ? 234 ALA A C 1 ATOM 1780 O O . ALA A 1 232 ? 91.077 -15.905 -8.130 1.00 12.61 ? 234 ALA A O 1 ATOM 1781 C CB . ALA A 1 232 ? 92.601 -14.715 -5.746 1.00 12.10 ? 234 ALA A CB 1 ATOM 1782 N N . PRO A 1 233 ? 90.093 -13.897 -7.860 1.00 14.96 ? 235 PRO A N 1 ATOM 1783 C CA . PRO A 1 233 ? 89.765 -13.799 -9.281 1.00 15.25 ? 235 PRO A CA 1 ATOM 1784 C C . PRO A 1 233 ? 91.025 -13.767 -10.144 1.00 15.86 ? 235 PRO A C 1 ATOM 1785 O O . PRO A 1 233 ? 92.060 -13.266 -9.708 1.00 14.61 ? 235 PRO A O 1 ATOM 1786 C CB . PRO A 1 233 ? 89.029 -12.459 -9.376 1.00 16.34 ? 235 PRO A CB 1 ATOM 1787 C CG . PRO A 1 233 ? 89.564 -11.657 -8.236 1.00 17.03 ? 235 PRO A CG 1 ATOM 1788 C CD . PRO A 1 233 ? 89.824 -12.643 -7.134 1.00 15.50 ? 235 PRO A CD 1 ATOM 1789 N N . ALA A 1 234 ? 90.941 -14.325 -11.348 1.00 16.73 ? 236 ALA A N 1 ATOM 1790 C CA . ALA A 1 234 ? 91.985 -14.138 -12.350 1.00 16.04 ? 236 ALA A CA 1 ATOM 1791 C C . ALA A 1 234 ? 92.280 -12.651 -12.536 1.00 15.99 ? 236 ALA A C 1 ATOM 1792 O O . ALA A 1 234 ? 91.448 -11.801 -12.216 1.00 16.90 ? 236 ALA A O 1 ATOM 1793 C CB . ALA A 1 234 ? 91.565 -14.764 -13.671 1.00 17.29 ? 236 ALA A CB 1 ATOM 1794 N N . GLY A 1 235 ? 93.466 -12.338 -13.043 1.00 14.73 ? 237 GLY A N 1 ATOM 1795 C CA . GLY A 1 235 ? 93.830 -10.948 -13.300 1.00 14.73 ? 237 GLY A CA 1 ATOM 1796 C C . GLY A 1 235 ? 95.327 -10.751 -13.413 1.00 14.91 ? 237 GLY A C 1 ATOM 1797 O O . GLY A 1 235 ? 96.107 -11.631 -13.036 1.00 14.49 ? 237 GLY A O 1 ATOM 1798 N N . SER A 1 236 ? 95.730 -9.594 -13.932 1.00 14.13 ? 238 SER A N 1 ATOM 1799 C CA . SER A 1 236 ? 97.143 -9.305 -14.157 1.00 14.61 ? 238 SER A CA 1 ATOM 1800 C C . SER A 1 236 ? 97.864 -8.878 -12.881 1.00 14.03 ? 238 SER A C 1 ATOM 1801 O O . SER A 1 236 ? 99.093 -8.848 -12.839 1.00 15.06 ? 238 SER A O 1 ATOM 1802 C CB . SER A 1 236 ? 97.312 -8.236 -15.241 1.00 14.61 ? 238 SER A CB 1 ATOM 1803 O OG . SER A 1 236 ? 96.634 -7.043 -14.888 1.00 15.26 ? 238 SER A OG 1 ATOM 1804 N N . GLY A 1 237 ? 97.100 -8.547 -11.846 1.00 13.91 ? 239 GLY A N 1 ATOM 1805 C CA . GLY A 1 237 ? 97.677 -8.251 -10.537 1.00 12.73 ? 239 GLY A CA 1 ATOM 1806 C C . GLY A 1 237 ? 98.380 -9.467 -9.964 1.00 12.47 ? 239 GLY A C 1 ATOM 1807 O O . GLY A 1 237 ? 98.203 -10.584 -10.454 1.00 13.17 ? 239 GLY A O 1 ATOM 1808 N N . SER A 1 238 ? 99.181 -9.258 -8.925 1.00 10.95 ? 240 SER A N 1 ATOM 1809 C CA . SER A 1 238 ? 99.829 -10.375 -8.248 1.00 11.35 ? 240 SER A CA 1 ATOM 1810 C C . SER A 1 238 ? 98.782 -11.226 -7.537 1.00 10.81 ? 240 SER A C 1 ATOM 1811 O O . SER A 1 238 ? 97.660 -10.780 -7.301 1.00 9.39 ? 240 SER A O 1 ATOM 1812 C CB . SER A 1 238 ? 100.878 -9.877 -7.251 1.00 10.94 ? 240 SER A CB 1 ATOM 1813 O OG . SER A 1 238 ? 100.272 -9.228 -6.145 1.00 10.04 ? 240 SER A OG 1 ATOM 1814 N N . LEU A 1 239 ? 99.145 -12.460 -7.210 1.00 10.72 ? 241 LEU A N 1 ATOM 1815 C CA . LEU A 1 239 ? 98.244 -13.324 -6.466 1.00 10.71 ? 241 LEU A CA 1 ATOM 1816 C C . LEU A 1 239 ? 97.796 -12.672 -5.162 1.00 10.32 ? 241 LEU A C 1 ATOM 1817 O O . LEU A 1 239 ? 96.627 -12.736 -4.807 1.00 10.04 ? 241 LEU A O 1 ATOM 1818 C CB . LEU A 1 239 ? 98.900 -14.674 -6.178 1.00 11.13 ? 241 LEU A CB 1 ATOM 1819 C CG . LEU A 1 239 ? 98.028 -15.638 -5.374 1.00 11.15 ? 241 LEU A CG 1 ATOM 1820 C CD1 . LEU A 1 239 ? 96.755 -15.971 -6.140 1.00 11.27 ? 241 LEU A CD1 1 ATOM 1821 C CD2 . LEU A 1 239 ? 98.807 -16.897 -5.032 1.00 11.37 ? 241 LEU A CD2 1 ATOM 1822 N N . GLN A 1 240 ? 98.726 -12.054 -4.442 1.00 11.04 ? 242 GLN A N 1 ATOM 1823 C CA . GLN A 1 240 ? 98.377 -11.450 -3.162 1.00 11.69 ? 242 GLN A CA 1 ATOM 1824 C C . GLN A 1 240 ? 97.402 -10.301 -3.362 1.00 11.24 ? 242 GLN A C 1 ATOM 1825 O O . GLN A 1 240 ? 96.463 -10.131 -2.583 1.00 11.49 ? 242 GLN A O 1 ATOM 1826 C CB . GLN A 1 240 ? 99.609 -10.955 -2.409 1.00 13.14 ? 242 GLN A CB 1 ATOM 1827 C CG . GLN A 1 240 ? 99.297 -10.533 -0.979 1.00 13.80 ? 242 GLN A CG 1 ATOM 1828 C CD . GLN A 1 240 ? 98.853 -11.699 -0.116 1.00 14.63 ? 242 GLN A CD 1 ATOM 1829 O OE1 . GLN A 1 240 ? 97.737 -11.714 0.411 1.00 18.39 ? 242 GLN A OE1 1 ATOM 1830 N NE2 . GLN A 1 240 ? 99.713 -12.703 0.004 1.00 14.35 ? 242 GLN A NE2 1 ATOM 1831 N N . ALA A 1 241 ? 97.629 -9.518 -4.413 1.00 10.49 ? 243 ALA A N 1 ATOM 1832 C CA . ALA A 1 241 ? 96.788 -8.366 -4.698 1.00 9.90 ? 243 ALA A CA 1 ATOM 1833 C C . ALA A 1 241 ? 95.363 -8.819 -4.972 1.00 9.80 ? 243 ALA A C 1 ATOM 1834 O O . ALA A 1 241 ? 94.407 -8.212 -4.492 1.00 10.01 ? 243 ALA A O 1 ATOM 1835 C CB . ALA A 1 241 ? 97.336 -7.583 -5.881 1.00 9.56 ? 243 ALA A CB 1 ATOM 1836 N N . ARG A 1 242 ? 95.226 -9.902 -5.730 1.00 9.59 ? 244 ARG A N 1 ATOM 1837 C CA . ARG A 1 242 ? 93.910 -10.379 -6.133 1.00 9.57 ? 244 ARG A CA 1 ATOM 1838 C C . ARG A 1 242 ? 93.190 -11.109 -4.999 1.00 9.44 ? 244 ARG A C 1 ATOM 1839 O O . ARG A 1 242 ? 91.964 -11.034 -4.882 1.00 8.88 ? 244 ARG A O 1 ATOM 1840 C CB . ARG A 1 242 ? 94.011 -11.249 -7.390 1.00 10.46 ? 244 ARG A CB 1 ATOM 1841 C CG . ARG A 1 242 ? 94.553 -10.491 -8.599 1.00 10.59 ? 244 ARG A CG 1 ATOM 1842 C CD . ARG A 1 242 ? 94.635 -11.364 -9.843 1.00 11.66 ? 244 ARG A CD 1 ATOM 1843 N NE . ARG A 1 242 ? 95.830 -12.210 -9.862 1.00 12.07 ? 244 ARG A NE 1 ATOM 1844 C CZ . ARG A 1 242 ? 95.827 -13.517 -9.614 1.00 12.10 ? 244 ARG A CZ 1 ATOM 1845 N NH1 . ARG A 1 242 ? 94.698 -14.136 -9.292 1.00 11.67 ? 244 ARG A NH1 1 ATOM 1846 N NH2 . ARG A 1 242 ? 96.956 -14.206 -9.675 1.00 12.93 ? 244 ARG A NH2 1 ATOM 1847 N N . ALA A 1 243 ? 93.957 -11.774 -4.137 1.00 8.98 ? 245 ALA A N 1 ATOM 1848 C CA . ALA A 1 243 ? 93.404 -12.316 -2.894 1.00 9.22 ? 245 ALA A CA 1 ATOM 1849 C C . ALA A 1 243 ? 92.919 -11.194 -1.981 1.00 9.71 ? 245 ALA A C 1 ATOM 1850 O O . ALA A 1 243 ? 91.819 -11.261 -1.427 1.00 9.85 ? 245 ALA A O 1 ATOM 1851 C CB . ALA A 1 243 ? 94.436 -13.173 -2.177 1.00 8.82 ? 245 ALA A CB 1 ATOM 1852 N N . ASP A 1 244 ? 93.759 -10.179 -1.804 1.00 10.20 ? 246 ASP A N 1 ATOM 1853 C CA . ASP A 1 244 ? 93.407 -9.028 -0.980 1.00 10.39 ? 246 ASP A CA 1 ATOM 1854 C C . ASP A 1 244 ? 92.141 -8.359 -1.510 1.00 9.84 ? 246 ASP A C 1 ATOM 1855 O O . ASP A 1 244 ? 91.299 -7.893 -0.735 1.00 9.97 ? 246 ASP A O 1 ATOM 1856 C CB . ASP A 1 244 ? 94.550 -8.006 -0.965 1.00 11.38 ? 246 ASP A CB 1 ATOM 1857 C CG . ASP A 1 244 ? 95.709 -8.420 -0.071 1.00 12.58 ? 246 ASP A CG 1 ATOM 1858 O OD1 . ASP A 1 244 ? 95.622 -9.456 0.624 1.00 14.15 ? 246 ASP A OD1 1 ATOM 1859 O OD2 . ASP A 1 244 ? 96.717 -7.686 -0.058 1.00 12.85 ? 246 ASP A OD2 1 ATOM 1860 N N . LEU A 1 245 ? 92.041 -8.259 -2.834 1.00 9.18 ? 247 LEU A N 1 ATOM 1861 C CA . LEU A 1 245 ? 90.878 -7.661 -3.474 1.00 9.10 ? 247 LEU A CA 1 ATOM 1862 C C . LEU A 1 245 ? 89.600 -8.420 -3.113 1.00 8.98 ? 247 LEU A C 1 ATOM 1863 O O . LEU A 1 245 ? 88.574 -7.813 -2.803 1.00 8.40 ? 247 LEU A O 1 ATOM 1864 C CB . LEU A 1 245 ? 91.063 -7.618 -4.996 1.00 9.16 ? 247 LEU A CB 1 ATOM 1865 C CG . LEU A 1 245 ? 89.824 -7.272 -5.822 1.00 9.87 ? 247 LEU A CG 1 ATOM 1866 C CD1 . LEU A 1 245 ? 89.381 -5.840 -5.560 1.00 9.76 ? 247 LEU A CD1 1 ATOM 1867 C CD2 . LEU A 1 245 ? 90.089 -7.499 -7.304 1.00 10.49 ? 247 LEU A CD2 1 ATOM 1868 N N . LEU A 1 246 ? 89.671 -9.747 -3.120 1.00 8.51 ? 248 LEU A N 1 ATOM 1869 C CA . LEU A 1 246 ? 88.493 -10.551 -2.804 1.00 8.66 ? 248 LEU A CA 1 ATOM 1870 C C . LEU A 1 246 ? 88.076 -10.360 -1.349 1.00 8.75 ? 248 LEU A C 1 ATOM 1871 O O . LEU A 1 246 ? 86.891 -10.205 -1.052 1.00 9.07 ? 248 LEU A O 1 ATOM 1872 C CB . LEU A 1 246 ? 88.734 -12.031 -3.111 1.00 8.18 ? 248 LEU A CB 1 ATOM 1873 C CG . LEU A 1 246 ? 87.543 -12.978 -2.902 1.00 8.32 ? 248 LEU A CG 1 ATOM 1874 C CD1 . LEU A 1 246 ? 86.344 -12.585 -3.754 1.00 8.31 ? 248 LEU A CD1 1 ATOM 1875 C CD2 . LEU A 1 246 ? 87.950 -14.415 -3.175 1.00 7.95 ? 248 LEU A CD2 1 ATOM 1876 N N . GLY A 1 247 ? 89.057 -10.336 -0.451 1.00 8.74 ? 249 GLY A N 1 ATOM 1877 C CA . GLY A 1 247 ? 88.806 -10.017 0.950 1.00 8.31 ? 249 GLY A CA 1 ATOM 1878 C C . GLY A 1 247 ? 88.085 -8.692 1.106 1.00 8.49 ? 249 GLY A C 1 ATOM 1879 O O . GLY A 1 247 ? 87.105 -8.590 1.845 1.00 8.21 ? 249 GLY A O 1 ATOM 1880 N N . ALA A 1 248 ? 88.576 -7.668 0.415 1.00 8.42 ? 250 ALA A N 1 ATOM 1881 C CA . ALA A 1 248 ? 88.004 -6.331 0.534 1.00 8.47 ? 250 ALA A CA 1 ATOM 1882 C C . ALA A 1 248 ? 86.583 -6.288 -0.019 1.00 8.60 ? 250 ALA A C 1 ATOM 1883 O O . ALA A 1 248 ? 85.725 -5.576 0.496 1.00 8.28 ? 250 ALA A O 1 ATOM 1884 C CB . ALA A 1 248 ? 88.886 -5.309 -0.167 1.00 8.25 ? 250 ALA A CB 1 ATOM 1885 N N . ARG A 1 249 ? 86.336 -7.044 -1.080 1.00 9.47 ? 251 ARG A N 1 ATOM 1886 C CA . ARG A 1 249 ? 85.009 -7.063 -1.678 1.00 9.75 ? 251 ARG A CA 1 ATOM 1887 C C . ARG A 1 249 ? 83.990 -7.822 -0.828 1.00 9.37 ? 251 ARG A C 1 ATOM 1888 O O . ARG A 1 249 ? 82.794 -7.536 -0.883 1.00 9.33 ? 251 ARG A O 1 ATOM 1889 C CB . ARG A 1 249 ? 85.068 -7.576 -3.120 1.00 11.51 ? 251 ARG A CB 1 ATOM 1890 C CG . ARG A 1 249 ? 85.513 -6.490 -4.092 1.00 12.60 ? 251 ARG A CG 1 ATOM 1891 C CD . ARG A 1 249 ? 85.529 -6.946 -5.538 1.00 13.35 ? 251 ARG A CD 1 ATOM 1892 N NE . ARG A 1 249 ? 84.197 -7.240 -6.060 1.00 13.06 ? 251 ARG A NE 1 ATOM 1893 C CZ . ARG A 1 249 ? 83.408 -6.362 -6.678 1.00 12.74 ? 251 ARG A CZ 1 ATOM 1894 N NH1 . ARG A 1 249 ? 83.757 -5.084 -6.771 1.00 13.34 ? 251 ARG A NH1 1 ATOM 1895 N NH2 . ARG A 1 249 ? 82.234 -6.756 -7.151 1.00 11.91 ? 251 ARG A NH2 1 ATOM 1896 N N . MET A 1 250 ? 84.475 -8.727 0.019 1.00 8.98 ? 252 MET A N 1 ATOM 1897 C CA . MET A 1 250 ? 83.626 -9.360 1.027 1.00 9.19 ? 252 MET A CA 1 ATOM 1898 C C . MET A 1 250 ? 83.264 -8.404 2.158 1.00 8.61 ? 252 MET A C 1 ATOM 1899 O O . MET A 1 250 ? 82.134 -8.404 2.643 1.00 8.74 ? 252 MET A O 1 ATOM 1900 C CB . MET A 1 250 ? 84.304 -10.604 1.607 1.00 9.90 ? 252 MET A CB 1 ATOM 1901 C CG . MET A 1 250 ? 84.255 -11.812 0.692 1.00 11.04 ? 252 MET A CG 1 ATOM 1902 S SD . MET A 1 250 ? 85.089 -13.236 1.422 1.00 12.93 ? 252 MET A SD 1 ATOM 1903 C CE . MET A 1 250 ? 85.204 -14.305 -0.009 1.00 12.02 ? 252 MET A CE 1 ATOM 1904 N N . VAL A 1 251 ? 84.239 -7.624 2.610 1.00 8.43 ? 253 VAL A N 1 ATOM 1905 C CA . VAL A 1 251 ? 84.034 -6.747 3.757 1.00 8.36 ? 253 VAL A CA 1 ATOM 1906 C C . VAL A 1 251 ? 83.335 -5.454 3.340 1.00 8.11 ? 253 VAL A C 1 ATOM 1907 O O . VAL A 1 251 ? 82.422 -4.984 4.022 1.00 7.52 ? 253 VAL A O 1 ATOM 1908 C CB . VAL A 1 251 ? 85.367 -6.415 4.461 1.00 8.56 ? 253 VAL A CB 1 ATOM 1909 C CG1 . VAL A 1 251 ? 85.157 -5.364 5.541 1.00 8.37 ? 253 VAL A CG1 1 ATOM 1910 C CG2 . VAL A 1 251 ? 85.988 -7.675 5.048 1.00 8.33 ? 253 VAL A CG2 1 ATOM 1911 N N . GLY A 1 252 ? 83.752 -4.904 2.203 1.00 7.84 ? 254 GLY A N 1 ATOM 1912 C CA . GLY A 1 252 ? 83.320 -3.572 1.781 1.00 7.96 ? 254 GLY A CA 1 ATOM 1913 C C . GLY A 1 252 ? 84.350 -2.499 2.086 1.00 7.89 ? 254 GLY A C 1 ATOM 1914 O O . GLY A 1 252 ? 84.167 -1.335 1.733 1.00 7.92 ? 254 GLY A O 1 ATOM 1915 N N . ARG A 1 253 ? 85.419 -2.887 2.776 1.00 7.81 ? 255 ARG A N 1 ATOM 1916 C CA . ARG A 1 253 ? 86.557 -1.998 3.019 1.00 7.98 ? 255 ARG A CA 1 ATOM 1917 C C . ARG A 1 253 ? 87.858 -2.770 2.845 1.00 8.41 ? 255 ARG A C 1 ATOM 1918 O O . ARG A 1 253 ? 87.902 -3.975 3.076 1.00 8.44 ? 255 ARG A O 1 ATOM 1919 C CB . ARG A 1 253 ? 86.514 -1.427 4.443 1.00 7.89 ? 255 ARG A CB 1 ATOM 1920 C CG . ARG A 1 253 ? 85.303 -0.571 4.756 1.00 7.93 ? 255 ARG A CG 1 ATOM 1921 C CD . ARG A 1 253 ? 85.441 0.097 6.118 1.00 8.25 ? 255 ARG A CD 1 ATOM 1922 N NE . ARG A 1 253 ? 84.318 0.993 6.382 1.00 8.06 ? 255 ARG A NE 1 ATOM 1923 C CZ . ARG A 1 253 ? 84.279 2.273 6.027 1.00 8.39 ? 255 ARG A CZ 1 ATOM 1924 N NH1 . ARG A 1 253 ? 85.324 2.831 5.427 1.00 8.44 ? 255 ARG A NH1 1 ATOM 1925 N NH2 . ARG A 1 253 ? 83.194 2.999 6.276 1.00 8.28 ? 255 ARG A NH2 1 ATOM 1926 N N . TRP A 1 254 ? 88.918 -2.071 2.450 1.00 8.90 ? 256 TRP A N 1 ATOM 1927 C CA . TRP A 1 254 ? 90.265 -2.621 2.534 1.00 8.99 ? 256 TRP A CA 1 ATOM 1928 C C . TRP A 1 254 ? 90.719 -2.634 3.990 1.00 9.17 ? 256 TRP A C 1 ATOM 1929 O O . TRP A 1 254 ? 90.098 -2.007 4.843 1.00 9.15 ? 256 TRP A O 1 ATOM 1930 C CB . TRP A 1 254 ? 91.230 -1.791 1.686 1.00 9.29 ? 256 TRP A CB 1 ATOM 1931 C CG . TRP A 1 254 ? 90.840 -1.744 0.244 1.00 9.52 ? 256 TRP A CG 1 ATOM 1932 C CD1 . TRP A 1 254 ? 90.002 -0.848 -0.348 1.00 9.60 ? 256 TRP A CD1 1 ATOM 1933 C CD2 . TRP A 1 254 ? 91.233 -2.665 -0.778 1.00 9.70 ? 256 TRP A CD2 1 ATOM 1934 N NE1 . TRP A 1 254 ? 89.880 -1.127 -1.688 1.00 9.86 ? 256 TRP A NE1 1 ATOM 1935 C CE2 . TRP A 1 254 ? 90.618 -2.246 -1.976 1.00 10.19 ? 256 TRP A CE2 1 ATOM 1936 C CE3 . TRP A 1 254 ? 92.066 -3.789 -0.803 1.00 9.30 ? 256 TRP A CE3 1 ATOM 1937 C CZ2 . TRP A 1 254 ? 90.788 -2.926 -3.181 1.00 10.16 ? 256 TRP A CZ2 1 ATOM 1938 C CZ3 . TRP A 1 254 ? 92.226 -4.470 -1.999 1.00 9.48 ? 256 TRP A CZ3 1 ATOM 1939 C CH2 . TRP A 1 254 ? 91.599 -4.030 -3.174 1.00 9.34 ? 256 TRP A CH2 1 ATOM 1940 N N . LYS A 1 255 ? 91.790 -3.365 4.275 1.00 9.89 ? 257 LYS A N 1 ATOM 1941 C CA . LYS A 1 255 ? 92.255 -3.511 5.650 1.00 10.02 ? 257 LYS A CA 1 ATOM 1942 C C . LYS A 1 255 ? 92.649 -2.175 6.282 1.00 10.14 ? 257 LYS A C 1 ATOM 1943 O O . LYS A 1 255 ? 92.628 -2.028 7.502 1.00 10.81 ? 257 LYS A O 1 ATOM 1944 C CB . LYS A 1 255 ? 93.416 -4.505 5.724 1.00 11.16 ? 257 LYS A CB 1 ATOM 1945 C CG . LYS A 1 255 ? 93.002 -5.944 5.461 1.00 12.00 ? 257 LYS A CG 1 ATOM 1946 C CD . LYS A 1 255 ? 94.186 -6.893 5.550 1.00 12.99 ? 257 LYS A CD 1 ATOM 1947 C CE . LYS A 1 255 ? 93.741 -8.329 5.328 1.00 14.83 ? 257 LYS A CE 1 ATOM 1948 N NZ . LYS A 1 255 ? 94.878 -9.288 5.395 1.00 16.00 ? 257 LYS A NZ 1 ATOM 1949 N N . SER A 1 256 ? 92.980 -1.195 5.449 1.00 10.00 ? 258 SER A N 1 ATOM 1950 C CA . SER A 1 256 ? 93.362 0.123 5.949 1.00 10.20 ? 258 SER A CA 1 ATOM 1951 C C . SER A 1 256 ? 92.137 0.882 6.448 1.00 9.94 ? 258 SER A C 1 ATOM 1952 O O . SER A 1 256 ? 92.263 1.907 7.120 1.00 10.18 ? 258 SER A O 1 ATOM 1953 C CB . SER A 1 256 ? 94.035 0.931 4.844 1.00 10.79 ? 258 SER A CB 1 ATOM 1954 O OG . SER A 1 256 ? 93.055 1.495 3.992 1.00 10.85 ? 258 SER A OG 1 ATOM 1955 N N . GLY A 1 257 ? 90.956 0.396 6.085 1.00 9.68 ? 259 GLY A N 1 ATOM 1956 C CA . GLY A 1 257 ? 89.719 1.120 6.354 1.00 10.31 ? 259 GLY A CA 1 ATOM 1957 C C . GLY A 1 257 ? 89.160 1.863 5.152 1.00 10.28 ? 259 GLY A C 1 ATOM 1958 O O . GLY A 1 257 ? 88.027 2.344 5.187 1.00 10.37 ? 259 GLY A O 1 ATOM 1959 N N . ALA A 1 258 ? 89.950 1.980 4.090 1.00 10.47 ? 260 ALA A N 1 ATOM 1960 C CA . ALA A 1 258 ? 89.463 2.632 2.876 1.00 10.35 ? 260 ALA A CA 1 ATOM 1961 C C . ALA A 1 258 ? 88.259 1.876 2.321 1.00 10.06 ? 260 ALA A C 1 ATOM 1962 O O . ALA A 1 258 ? 88.324 0.665 2.115 1.00 10.03 ? 260 ALA A O 1 ATOM 1963 C CB . ALA A 1 258 ? 90.567 2.731 1.832 1.00 10.44 ? 260 ALA A CB 1 ATOM 1964 N N . PRO A 1 259 ? 87.135 2.584 2.126 1.00 10.00 ? 261 PRO A N 1 ATOM 1965 C CA . PRO A 1 259 ? 85.932 1.964 1.574 1.00 10.02 ? 261 PRO A CA 1 ATOM 1966 C C . PRO A 1 259 ? 86.116 1.627 0.098 1.00 10.48 ? 261 PRO A C 1 ATOM 1967 O O . PRO A 1 259 ? 86.536 2.483 -0.683 1.00 10.76 ? 261 PRO A O 1 ATOM 1968 C CB . PRO A 1 259 ? 84.871 3.056 1.739 1.00 10.26 ? 261 PRO A CB 1 ATOM 1969 C CG . PRO A 1 259 ? 85.639 4.333 1.713 1.00 10.17 ? 261 PRO A CG 1 ATOM 1970 C CD . PRO A 1 259 ? 86.952 4.024 2.384 1.00 9.89 ? 261 PRO A CD 1 ATOM 1971 N N . ILE A 1 260 ? 85.843 0.381 -0.277 1.00 10.19 ? 262 ILE A N 1 ATOM 1972 C CA . ILE A 1 260 ? 86.082 -0.046 -1.651 1.00 10.60 ? 262 ILE A CA 1 ATOM 1973 C C . ILE A 1 260 ? 85.210 0.745 -2.619 1.00 10.78 ? 262 ILE A C 1 ATOM 1974 O O . ILE A 1 260 ? 85.578 0.944 -3.774 1.00 11.05 ? 262 ILE A O 1 ATOM 1975 C CB . ILE A 1 260 ? 85.838 -1.554 -1.848 1.00 10.83 ? 262 ILE A CB 1 ATOM 1976 C CG1 . ILE A 1 260 ? 84.359 -1.899 -1.659 1.00 10.36 ? 262 ILE A CG1 1 ATOM 1977 C CG2 . ILE A 1 260 ? 86.708 -2.363 -0.903 1.00 10.98 ? 262 ILE A CG2 1 ATOM 1978 C CD1 . ILE A 1 260 ? 84.047 -3.353 -1.935 1.00 11.07 ? 262 ILE A CD1 1 ATOM 1979 N N . ASP A 1 261 ? 84.062 1.211 -2.137 1.00 10.90 ? 263 ASP A N 1 ATOM 1980 C CA . ASP A 1 261 ? 83.166 2.016 -2.959 1.00 11.67 ? 263 ASP A CA 1 ATOM 1981 C C . ASP A 1 261 ? 83.879 3.225 -3.547 1.00 12.89 ? 263 ASP A C 1 ATOM 1982 O O . ASP A 1 261 ? 83.583 3.647 -4.666 1.00 13.53 ? 263 ASP A O 1 ATOM 1983 C CB . ASP A 1 261 ? 81.951 2.479 -2.155 1.00 11.82 ? 263 ASP A CB 1 ATOM 1984 C CG . ASP A 1 261 ? 80.877 3.098 -3.032 1.00 12.46 ? 263 ASP A CG 1 ATOM 1985 O OD1 . ASP A 1 261 ? 80.368 2.394 -3.928 1.00 12.24 ? 263 ASP A OD1 1 ATOM 1986 O OD2 . ASP A 1 261 ? 80.536 4.282 -2.822 1.00 12.98 ? 263 ASP A OD2 1 ATOM 1987 N N . LEU A 1 262 ? 84.795 3.801 -2.775 1.00 12.69 ? 264 LEU A N 1 ATOM 1988 C CA . LEU A 1 262 ? 85.547 4.970 -3.225 1.00 13.49 ? 264 LEU A CA 1 ATOM 1989 C C . LEU A 1 262 ? 86.886 4.609 -3.869 1.00 13.86 ? 264 LEU A C 1 ATOM 1990 O O . LEU A 1 262 ? 87.523 5.453 -4.501 1.00 13.71 ? 264 LEU A O 1 ATOM 1991 C CB . LEU A 1 262 ? 85.765 5.945 -2.067 1.00 13.04 ? 264 LEU A CB 1 ATOM 1992 C CG . LEU A 1 262 ? 84.500 6.531 -1.436 1.00 13.58 ? 264 LEU A CG 1 ATOM 1993 C CD1 . LEU A 1 262 ? 84.853 7.429 -0.260 1.00 13.88 ? 264 LEU A CD1 1 ATOM 1994 C CD2 . LEU A 1 262 ? 83.692 7.296 -2.474 1.00 14.41 ? 264 LEU A CD2 1 ATOM 1995 N N . THR A 1 263 ? 87.327 3.370 -3.677 1.00 12.99 ? 265 THR A N 1 ATOM 1996 C CA . THR A 1 263 ? 88.583 2.907 -4.264 1.00 13.44 ? 265 THR A CA 1 ATOM 1997 C C . THR A 1 263 ? 88.517 1.421 -4.625 1.00 12.81 ? 265 THR A C 1 ATOM 1998 O O . THR A 1 263 ? 89.026 0.572 -3.895 1.00 12.26 ? 265 THR A O 1 ATOM 1999 C CB . THR A 1 263 ? 89.792 3.200 -3.347 1.00 13.73 ? 265 THR A CB 1 ATOM 2000 O OG1 . THR A 1 263 ? 90.989 2.682 -3.941 1.00 15.09 ? 265 THR A OG1 1 ATOM 2001 C CG2 . THR A 1 263 ? 89.601 2.575 -1.968 1.00 12.67 ? 265 THR A CG2 1 ATOM 2002 N N . PRO A 1 264 ? 87.875 1.107 -5.762 1.00 12.89 ? 266 PRO A N 1 ATOM 2003 C CA . PRO A 1 264 ? 87.364 -0.244 -5.997 1.00 12.70 ? 266 PRO A CA 1 ATOM 2004 C C . PRO A 1 264 ? 88.443 -1.269 -6.334 1.00 13.34 ? 266 PRO A C 1 ATOM 2005 O O . PRO A 1 264 ? 88.210 -2.465 -6.186 1.00 12.75 ? 266 PRO A O 1 ATOM 2006 C CB . PRO A 1 264 ? 86.414 -0.063 -7.189 1.00 13.32 ? 266 PRO A CB 1 ATOM 2007 C CG . PRO A 1 264 ? 86.060 1.389 -7.188 1.00 14.27 ? 266 PRO A CG 1 ATOM 2008 C CD . PRO A 1 264 ? 87.288 2.091 -6.688 1.00 13.14 ? 266 PRO A CD 1 ATOM 2009 N N . THR A 1 265 ? 89.603 -0.811 -6.800 1.00 13.95 ? 267 THR A N 1 ATOM 2010 C CA . THR A 1 265 ? 90.597 -1.719 -7.371 1.00 15.17 ? 267 THR A CA 1 ATOM 2011 C C . THR A 1 265 ? 91.849 -1.900 -6.509 1.00 15.97 ? 267 THR A C 1 ATOM 2012 O O . THR A 1 265 ? 92.555 -2.900 -6.636 1.00 16.71 ? 267 THR A O 1 ATOM 2013 C CB . THR A 1 265 ? 90.997 -1.317 -8.807 1.00 16.33 ? 267 THR A CB 1 ATOM 2014 O OG1 . THR A 1 265 ? 91.590 -0.012 -8.799 1.00 20.16 ? 267 THR A OG1 1 ATOM 2015 C CG2 . THR A 1 265 ? 89.781 -1.308 -9.718 1.00 15.99 ? 267 THR A CG2 1 ATOM 2016 N N . ALA A 1 266 ? 92.107 -0.952 -5.612 1.00 15.73 ? 268 ALA A N 1 ATOM 2017 C CA . ALA A 1 266 ? 93.268 -1.046 -4.728 1.00 16.12 ? 268 ALA A CA 1 ATOM 2018 C C . ALA A 1 266 ? 93.042 -0.325 -3.405 1.00 14.15 ? 268 ALA A C 1 ATOM 2019 O O . ALA A 1 266 ? 92.208 0.578 -3.312 1.00 13.85 ? 268 ALA A O 1 ATOM 2020 C CB . ALA A 1 266 ? 94.514 -0.513 -5.419 1.00 17.56 ? 268 ALA A CB 1 ATOM 2021 N N . ASP A 1 267 ? 93.770 -0.753 -2.377 1.00 13.85 ? 269 ASP A N 1 ATOM 2022 C CA . ASP A 1 267 ? 93.742 -0.077 -1.085 1.00 13.26 ? 269 ASP A CA 1 ATOM 2023 C C . ASP A 1 267 ? 94.292 1.335 -1.240 1.00 14.72 ? 269 ASP A C 1 ATOM 2024 O O . ASP A 1 267 ? 95.066 1.613 -2.157 1.00 14.89 ? 269 ASP A O 1 ATOM 2025 C CB . ASP A 1 267 ? 94.558 -0.858 -0.047 1.00 13.37 ? 269 ASP A CB 1 ATOM 2026 C CG . ASP A 1 267 ? 94.250 -0.437 1.384 1.00 12.79 ? 269 ASP A CG 1 ATOM 2027 O OD1 . ASP A 1 267 ? 93.570 0.590 1.580 1.00 13.06 ? 269 ASP A OD1 1 ATOM 2028 O OD2 . ASP A 1 267 ? 94.693 -1.135 2.320 1.00 13.80 ? 269 ASP A OD2 1 ATOM 2029 N N . ASP A 1 268 ? 93.854 2.228 -0.361 1.00 15.10 ? 270 ASP A N 1 ATOM 2030 C CA . ASP A 1 268 ? 94.311 3.613 -0.355 1.00 15.19 ? 270 ASP A CA 1 ATOM 2031 C C . ASP A 1 268 ? 94.472 4.036 1.099 1.00 14.81 ? 270 ASP A C 1 ATOM 2032 O O . ASP A 1 268 ? 93.519 4.496 1.719 1.00 13.38 ? 270 ASP A O 1 ATOM 2033 C CB . ASP A 1 268 ? 93.285 4.508 -1.059 1.00 14.53 ? 270 ASP A CB 1 ATOM 2034 C CG . ASP A 1 268 ? 93.673 5.981 -1.046 1.00 16.19 ? 270 ASP A CG 1 ATOM 2035 O OD1 . ASP A 1 268 ? 94.553 6.378 -0.254 1.00 16.06 ? 270 ASP A OD1 1 ATOM 2036 O OD2 . ASP A 1 268 ? 93.073 6.753 -1.823 1.00 17.17 ? 270 ASP A OD2 1 ATOM 2037 N N . PRO A 1 269 ? 95.664 3.799 1.668 1.00 15.09 ? 271 PRO A N 1 ATOM 2038 C CA . PRO A 1 269 ? 95.878 3.909 3.106 1.00 14.83 ? 271 PRO A CA 1 ATOM 2039 C C . PRO A 1 269 ? 95.646 5.320 3.644 1.00 14.32 ? 271 PRO A C 1 ATOM 2040 O O . PRO A 1 269 ? 95.180 5.478 4.772 1.00 13.70 ? 271 PRO A O 1 ATOM 2041 C CB . PRO A 1 269 ? 97.345 3.507 3.272 1.00 15.81 ? 271 PRO A CB 1 ATOM 2042 C CG . PRO A 1 269 ? 97.610 2.598 2.119 1.00 17.49 ? 271 PRO A CG 1 ATOM 2043 C CD . PRO A 1 269 ? 96.809 3.172 0.985 1.00 15.99 ? 271 PRO A CD 1 ATOM 2044 N N . ALA A 1 270 ? 95.990 6.335 2.858 1.00 13.71 ? 272 ALA A N 1 ATOM 2045 C CA . ALA A 1 270 ? 95.742 7.715 3.269 1.00 14.39 ? 272 ALA A CA 1 ATOM 2046 C C . ALA A 1 270 ? 94.245 7.963 3.435 1.00 13.99 ? 272 ALA A C 1 ATOM 2047 O O . ALA A 1 270 ? 93.814 8.637 4.370 1.00 13.29 ? 272 ALA A O 1 ATOM 2048 C CB . ALA A 1 270 ? 96.343 8.692 2.268 1.00 14.03 ? 272 ALA A CB 1 ATOM 2049 N N . LEU A 1 271 ? 93.454 7.394 2.532 1.00 13.40 ? 273 LEU A N 1 ATOM 2050 C CA . LEU A 1 271 ? 92.004 7.496 2.611 1.00 13.81 ? 273 LEU A CA 1 ATOM 2051 C C . LEU A 1 271 ? 91.461 6.731 3.819 1.00 13.87 ? 273 LEU A C 1 ATOM 2052 O O . LEU A 1 271 ? 90.560 7.204 4.514 1.00 14.27 ? 273 LEU A O 1 ATOM 2053 C CB . LEU A 1 271 ? 91.375 6.965 1.323 1.00 14.19 ? 273 LEU A CB 1 ATOM 2054 C CG . LEU A 1 271 ? 89.879 6.649 1.332 1.00 14.71 ? 273 LEU A CG 1 ATOM 2055 C CD1 . LEU A 1 271 ? 89.068 7.881 1.707 1.00 15.35 ? 273 LEU A CD1 1 ATOM 2056 C CD2 . LEU A 1 271 ? 89.463 6.124 -0.036 1.00 14.89 ? 273 LEU A CD2 1 ATOM 2057 N N . GLY A 1 272 ? 92.011 5.547 4.065 1.00 13.54 ? 274 GLY A N 1 ATOM 2058 C CA . GLY A 1 272 ? 91.552 4.711 5.168 1.00 12.97 ? 274 GLY A CA 1 ATOM 2059 C C . GLY A 1 272 ? 91.694 5.388 6.518 1.00 14.05 ? 274 GLY A C 1 ATOM 2060 O O . GLY A 1 272 ? 90.884 5.175 7.417 1.00 14.64 ? 274 GLY A O 1 ATOM 2061 N N . ALA A 1 273 ? 92.721 6.218 6.655 1.00 14.81 ? 275 ALA A N 1 ATOM 2062 C CA . ALA A 1 273 ? 93.058 6.816 7.942 1.00 16.73 ? 275 ALA A CA 1 ATOM 2063 C C . ALA A 1 273 ? 92.298 8.116 8.186 1.00 17.80 ? 275 ALA A C 1 ATOM 2064 O O . ALA A 1 273 ? 92.335 8.669 9.285 1.00 19.74 ? 275 ALA A O 1 ATOM 2065 C CB . ALA A 1 273 ? 94.558 7.051 8.037 1.00 15.99 ? 275 ALA A CB 1 ATOM 2066 N N . ASP A 1 274 ? 91.606 8.596 7.158 1.00 16.57 ? 276 ASP A N 1 ATOM 2067 C CA . ASP A 1 274 ? 91.039 9.939 7.180 1.00 17.12 ? 276 ASP A CA 1 ATOM 2068 C C . ASP A 1 274 ? 89.546 9.904 7.500 1.00 15.55 ? 276 ASP A C 1 ATOM 2069 O O . ASP A 1 274 ? 88.724 9.639 6.626 1.00 14.49 ? 276 ASP A O 1 ATOM 2070 C CB . ASP A 1 274 ? 91.274 10.640 5.838 1.00 17.82 ? 276 ASP A CB 1 ATOM 2071 C CG . ASP A 1 274 ? 90.866 12.104 5.863 1.00 19.63 ? 276 ASP A CG 1 ATOM 2072 O OD1 . ASP A 1 274 ? 90.210 12.524 6.840 1.00 19.26 ? 276 ASP A OD1 1 ATOM 2073 O OD2 . ASP A 1 274 ? 91.210 12.837 4.908 1.00 20.98 ? 276 ASP A OD2 1 ATOM 2074 N N . ALA A 1 275 ? 89.205 10.210 8.749 1.00 14.25 ? 277 ALA A N 1 ATOM 2075 C CA . ALA A 1 275 ? 87.824 10.137 9.214 1.00 14.22 ? 277 ALA A CA 1 ATOM 2076 C C . ALA A 1 275 ? 86.916 11.104 8.464 1.00 14.18 ? 277 ALA A C 1 ATOM 2077 O O . ALA A 1 275 ? 85.700 10.940 8.449 1.00 14.15 ? 277 ALA A O 1 ATOM 2078 C CB . ALA A 1 275 ? 87.753 10.395 10.711 1.00 14.84 ? 277 ALA A CB 1 ATOM 2079 N N . GLN A 1 276 ? 87.513 12.109 7.834 1.00 15.33 ? 278 GLN A N 1 ATOM 2080 C CA . GLN A 1 276 ? 86.749 13.069 7.052 1.00 14.93 ? 278 GLN A CA 1 ATOM 2081 C C . GLN A 1 276 ? 86.407 12.544 5.657 1.00 14.52 ? 278 GLN A C 1 ATOM 2082 O O . GLN A 1 276 ? 85.590 13.136 4.954 1.00 14.54 ? 278 GLN A O 1 ATOM 2083 C CB . GLN A 1 276 ? 87.501 14.399 6.953 1.00 17.92 ? 278 GLN A CB 1 ATOM 2084 C CG . GLN A 1 276 ? 87.620 15.144 8.273 1.00 18.54 ? 278 GLN A CG 1 ATOM 2085 C CD . GLN A 1 276 ? 86.285 15.665 8.768 1.00 19.40 ? 278 GLN A CD 1 ATOM 2086 O OE1 . GLN A 1 276 ? 85.484 16.192 7.994 1.00 20.06 ? 278 GLN A OE1 1 ATOM 2087 N NE2 . GLN A 1 276 ? 86.042 15.529 10.066 1.00 20.40 ? 278 GLN A NE2 1 ATOM 2088 N N . ARG A 1 277 ? 87.005 11.419 5.267 1.00 13.55 ? 279 ARG A N 1 ATOM 2089 C CA . ARG A 1 277 ? 86.789 10.877 3.924 1.00 13.32 ? 279 ARG A CA 1 ATOM 2090 C C . ARG A 1 277 ? 86.306 9.426 3.897 1.00 12.85 ? 279 ARG A C 1 ATOM 2091 O O . ARG A 1 277 ? 85.613 9.016 2.962 1.00 11.86 ? 279 ARG A O 1 ATOM 2092 C CB . ARG A 1 277 ? 88.056 11.012 3.080 1.00 15.60 ? 279 ARG A CB 1 ATOM 2093 C CG . ARG A 1 277 ? 88.451 12.446 2.770 1.00 16.64 ? 279 ARG A CG 1 ATOM 2094 C CD . ARG A 1 277 ? 89.386 12.493 1.573 1.00 20.50 ? 279 ARG A CD 1 ATOM 2095 N NE . ARG A 1 277 ? 90.698 11.936 1.891 1.00 22.55 ? 279 ARG A NE 1 ATOM 2096 C CZ . ARG A 1 277 ? 91.410 11.178 1.063 1.00 23.35 ? 279 ARG A CZ 1 ATOM 2097 N NH1 . ARG A 1 277 ? 90.934 10.872 -0.138 1.00 22.95 ? 279 ARG A NH1 1 ATOM 2098 N NH2 . ARG A 1 277 ? 92.600 10.728 1.435 1.00 23.68 ? 279 ARG A NH2 1 ATOM 2099 N N . ASN A 1 278 ? 86.704 8.639 4.894 1.00 11.23 ? 280 ASN A N 1 ATOM 2100 C CA . ASN A 1 278 ? 86.590 7.188 4.792 1.00 11.21 ? 280 ASN A CA 1 ATOM 2101 C C . ASN A 1 278 ? 85.159 6.666 4.966 1.00 11.27 ? 280 ASN A C 1 ATOM 2102 O O . ASN A 1 278 ? 84.903 5.475 4.796 1.00 11.27 ? 280 ASN A O 1 ATOM 2103 C CB . ASN A 1 278 ? 87.554 6.489 5.756 1.00 10.91 ? 280 ASN A CB 1 ATOM 2104 C CG . ASN A 1 278 ? 87.235 6.771 7.210 1.00 11.31 ? 280 ASN A CG 1 ATOM 2105 O OD1 . ASN A 1 278 ? 86.192 7.338 7.526 1.00 11.94 ? 280 ASN A OD1 1 ATOM 2106 N ND2 . ASN A 1 278 ? 88.115 6.338 8.106 1.00 10.78 ? 280 ASN A ND2 1 ATOM 2107 N N . ASN A 1 279 ? 84.227 7.564 5.273 1.00 10.37 ? 281 ASN A N 1 ATOM 2108 C CA . ASN A 1 279 ? 82.812 7.196 5.345 1.00 10.34 ? 281 ASN A CA 1 ATOM 2109 C C . ASN A 1 279 ? 81.930 8.043 4.429 1.00 10.49 ? 281 ASN A C 1 ATOM 2110 O O . ASN A 1 279 ? 80.701 7.961 4.470 1.00 9.97 ? 281 ASN A O 1 ATOM 2111 C CB . ASN A 1 279 ? 82.307 7.265 6.785 1.00 10.37 ? 281 ASN A CB 1 ATOM 2112 C CG . ASN A 1 279 ? 81.268 6.202 7.085 1.00 10.38 ? 281 ASN A CG 1 ATOM 2113 O OD1 . ASN A 1 279 ? 81.208 5.170 6.414 1.00 9.76 ? 281 ASN A OD1 1 ATOM 2114 N ND2 . ASN A 1 279 ? 80.441 6.452 8.090 1.00 10.11 ? 281 ASN A ND2 1 ATOM 2115 N N . ASN A 1 280 ? 82.576 8.819 3.568 1.00 10.71 ? 282 ASN A N 1 ATOM 2116 C CA . ASN A 1 280 ? 81.893 9.810 2.752 1.00 11.47 ? 282 ASN A CA 1 ATOM 2117 C C . ASN A 1 280 ? 81.395 9.224 1.426 1.00 11.51 ? 282 ASN A C 1 ATOM 2118 O O . ASN A 1 280 ? 81.877 9.590 0.351 1.00 11.72 ? 282 ASN A O 1 ATOM 2119 C CB . ASN A 1 280 ? 82.831 10.996 2.507 1.00 12.98 ? 282 ASN A CB 1 ATOM 2120 C CG . ASN A 1 280 ? 82.132 12.172 1.860 1.00 14.96 ? 282 ASN A CG 1 ATOM 2121 O OD1 . ASN A 1 280 ? 80.948 12.418 2.094 1.00 14.56 ? 282 ASN A OD1 1 ATOM 2122 N ND2 . ASN A 1 280 ? 82.876 12.923 1.061 1.00 16.95 ? 282 ASN A ND2 1 ATOM 2123 N N . PHE A 1 281 ? 80.424 8.316 1.510 1.00 10.67 ? 283 PHE A N 1 ATOM 2124 C CA . PHE A 1 281 ? 79.886 7.643 0.327 1.00 10.72 ? 283 PHE A CA 1 ATOM 2125 C C . PHE A 1 281 ? 78.480 7.095 0.580 1.00 10.50 ? 283 PHE A C 1 ATOM 2126 O O . PHE A 1 281 ? 78.074 6.914 1.728 1.00 10.31 ? 283 PHE A O 1 ATOM 2127 C CB . PHE A 1 281 ? 80.817 6.508 -0.120 1.00 10.56 ? 283 PHE A CB 1 ATOM 2128 C CG . PHE A 1 281 ? 80.942 5.392 0.884 1.00 10.36 ? 283 PHE A CG 1 ATOM 2129 C CD1 . PHE A 1 281 ? 81.881 5.458 1.898 1.00 10.27 ? 283 PHE A CD1 1 ATOM 2130 C CD2 . PHE A 1 281 ? 80.123 4.274 0.808 1.00 10.43 ? 283 PHE A CD2 1 ATOM 2131 C CE1 . PHE A 1 281 ? 81.992 4.441 2.830 1.00 10.24 ? 283 PHE A CE1 1 ATOM 2132 C CE2 . PHE A 1 281 ? 80.232 3.251 1.734 1.00 9.77 ? 283 PHE A CE2 1 ATOM 2133 C CZ . PHE A 1 281 ? 81.173 3.332 2.741 1.00 9.80 ? 283 PHE A CZ 1 ATOM 2134 N N . THR A 1 282 ? 77.759 6.802 -0.501 1.00 11.09 ? 284 THR A N 1 ATOM 2135 C CA . THR A 1 282 ? 76.366 6.358 -0.411 1.00 11.45 ? 284 THR A CA 1 ATOM 2136 C C . THR A 1 282 ? 76.128 5.073 -1.201 1.00 11.59 ? 284 THR A C 1 ATOM 2137 O O . THR A 1 282 ? 75.062 4.462 -1.094 1.00 10.87 ? 284 THR A O 1 ATOM 2138 C CB . THR A 1 282 ? 75.396 7.427 -0.949 1.00 11.95 ? 284 THR A CB 1 ATOM 2139 O OG1 . THR A 1 282 ? 75.564 7.550 -2.367 1.00 13.55 ? 284 THR A OG1 1 ATOM 2140 C CG2 . THR A 1 282 ? 75.653 8.775 -0.293 1.00 11.29 ? 284 THR A CG2 1 ATOM 2141 N N . TYR A 1 283 ? 77.132 4.677 -1.984 1.00 11.36 ? 285 TYR A N 1 ATOM 2142 C CA . TYR A 1 283 ? 77.026 3.588 -2.959 1.00 11.02 ? 285 TYR A CA 1 ATOM 2143 C C . TYR A 1 283 ? 76.556 4.042 -4.342 1.00 12.08 ? 285 TYR A C 1 ATOM 2144 O O . TYR A 1 283 ? 76.595 3.272 -5.301 1.00 12.03 ? 285 TYR A O 1 ATOM 2145 C CB . TYR A 1 283 ? 76.171 2.429 -2.434 1.00 11.12 ? 285 TYR A CB 1 ATOM 2146 C CG . TYR A 1 283 ? 76.781 1.743 -1.226 1.00 10.74 ? 285 TYR A CG 1 ATOM 2147 C CD1 . TYR A 1 283 ? 78.092 1.283 -1.257 1.00 10.50 ? 285 TYR A CD1 1 ATOM 2148 C CD2 . TYR A 1 283 ? 76.063 1.597 -0.049 1.00 10.30 ? 285 TYR A CD2 1 ATOM 2149 C CE1 . TYR A 1 283 ? 78.666 0.687 -0.149 1.00 10.49 ? 285 TYR A CE1 1 ATOM 2150 C CE2 . TYR A 1 283 ? 76.628 0.997 1.065 1.00 9.75 ? 285 TYR A CE2 1 ATOM 2151 C CZ . TYR A 1 283 ? 77.928 0.546 1.008 1.00 10.12 ? 285 TYR A CZ 1 ATOM 2152 O OH . TYR A 1 283 ? 78.505 -0.039 2.112 1.00 10.00 ? 285 TYR A OH 1 ATOM 2153 N N . SER A 1 284 ? 76.121 5.295 -4.441 1.00 12.81 ? 286 SER A N 1 ATOM 2154 C CA . SER A 1 284 ? 75.752 5.875 -5.726 1.00 12.87 ? 286 SER A CA 1 ATOM 2155 C C . SER A 1 284 ? 76.973 6.390 -6.486 1.00 13.68 ? 286 SER A C 1 ATOM 2156 O O . SER A 1 284 ? 77.946 6.850 -5.883 1.00 12.14 ? 286 SER A O 1 ATOM 2157 C CB . SER A 1 284 ? 74.741 7.005 -5.531 1.00 14.78 ? 286 SER A CB 1 ATOM 2158 O OG . SER A 1 284 ? 74.426 7.622 -6.765 1.00 16.68 ? 286 SER A OG 1 ATOM 2159 N N . HIS A 1 285 ? 76.922 6.291 -7.811 1.00 13.78 ? 287 HIS A N 1 ATOM 2160 C CA . HIS A 1 285 ? 78.013 6.749 -8.662 1.00 13.84 ? 287 HIS A CA 1 ATOM 2161 C C . HIS A 1 285 ? 77.447 7.294 -9.964 1.00 14.76 ? 287 HIS A C 1 ATOM 2162 O O . HIS A 1 285 ? 76.642 6.633 -10.620 1.00 14.44 ? 287 HIS A O 1 ATOM 2163 C CB . HIS A 1 285 ? 78.986 5.600 -8.961 1.00 13.64 ? 287 HIS A CB 1 ATOM 2164 C CG . HIS A 1 285 ? 79.644 5.040 -7.739 1.00 13.70 ? 287 HIS A CG 1 ATOM 2165 N ND1 . HIS A 1 285 ? 80.731 5.640 -7.141 1.00 13.73 ? 287 HIS A ND1 1 ATOM 2166 C CD2 . HIS A 1 285 ? 79.331 3.973 -6.967 1.00 13.52 ? 287 HIS A CD2 1 ATOM 2167 C CE1 . HIS A 1 285 ? 81.069 4.958 -6.062 1.00 13.79 ? 287 HIS A CE1 1 ATOM 2168 N NE2 . HIS A 1 285 ? 80.226 3.950 -5.926 1.00 13.09 ? 287 HIS A NE2 1 ATOM 2169 N N . ALA A 1 286 ? 77.853 8.506 -10.327 1.00 15.90 ? 288 ALA A N 1 ATOM 2170 C CA . ALA A 1 286 ? 77.406 9.106 -11.580 1.00 15.87 ? 288 ALA A CA 1 ATOM 2171 C C . ALA A 1 286 ? 77.769 8.212 -12.759 1.00 16.43 ? 288 ALA A C 1 ATOM 2172 O O . ALA A 1 286 ? 78.887 7.706 -12.846 1.00 16.69 ? 288 ALA A O 1 ATOM 2173 C CB . ALA A 1 286 ? 78.006 10.495 -11.754 1.00 18.17 ? 288 ALA A CB 1 ATOM 2174 N N . GLY A 1 287 ? 76.801 7.981 -13.638 1.00 17.41 ? 289 GLY A N 1 ATOM 2175 C CA . GLY A 1 287 ? 77.028 7.179 -14.834 1.00 19.19 ? 289 GLY A CA 1 ATOM 2176 C C . GLY A 1 287 ? 76.753 5.700 -14.628 1.00 19.61 ? 289 GLY A C 1 ATOM 2177 O O . GLY A 1 287 ? 76.814 4.914 -15.574 1.00 20.09 ? 289 GLY A O 1 ATOM 2178 N N . PHE A 1 288 ? 76.456 5.315 -13.390 1.00 17.92 ? 290 PHE A N 1 ATOM 2179 C CA . PHE A 1 288 ? 76.228 3.907 -13.064 1.00 17.40 ? 290 PHE A CA 1 ATOM 2180 C C . PHE A 1 288 ? 74.831 3.671 -12.499 1.00 16.89 ? 290 PHE A C 1 ATOM 2181 O O . PHE A 1 288 ? 74.311 4.483 -11.734 1.00 16.39 ? 290 PHE A O 1 ATOM 2182 C CB . PHE A 1 288 ? 77.279 3.401 -12.073 1.00 17.04 ? 290 PHE A CB 1 ATOM 2183 C CG . PHE A 1 288 ? 78.677 3.397 -12.620 1.00 16.60 ? 290 PHE A CG 1 ATOM 2184 C CD1 . PHE A 1 288 ? 79.460 4.540 -12.565 1.00 16.91 ? 290 PHE A CD1 1 ATOM 2185 C CD2 . PHE A 1 288 ? 79.218 2.245 -13.167 1.00 16.52 ? 290 PHE A CD2 1 ATOM 2186 C CE1 . PHE A 1 288 ? 80.750 4.538 -13.064 1.00 17.76 ? 290 PHE A CE1 1 ATOM 2187 C CE2 . PHE A 1 288 ? 80.510 2.234 -13.660 1.00 16.87 ? 290 PHE A CE2 1 ATOM 2188 C CZ . PHE A 1 288 ? 81.278 3.381 -13.604 1.00 17.20 ? 290 PHE A CZ 1 ATOM 2189 N N . ASP A 1 289 ? 74.243 2.536 -12.860 1.00 17.66 ? 291 ASP A N 1 ATOM 2190 C CA . ASP A 1 289 ? 72.915 2.166 -12.388 1.00 18.83 ? 291 ASP A CA 1 ATOM 2191 C C . ASP A 1 289 ? 72.994 1.510 -11.010 1.00 17.14 ? 291 ASP A C 1 ATOM 2192 O O . ASP A 1 289 ? 73.537 0.417 -10.865 1.00 15.46 ? 291 ASP A O 1 ATOM 2193 C CB . ASP A 1 289 ? 72.254 1.219 -13.391 1.00 20.65 ? 291 ASP A CB 1 ATOM 2194 C CG . ASP A 1 289 ? 70.973 0.612 -12.865 1.00 24.54 ? 291 ASP A CG 1 ATOM 2195 O OD1 . ASP A 1 289 ? 70.186 1.335 -12.216 1.00 28.51 ? 291 ASP A OD1 1 ATOM 2196 O OD2 . ASP A 1 289 ? 70.746 -0.591 -13.111 1.00 26.37 ? 291 ASP A OD2 1 ATOM 2197 N N . LEU A 1 290 ? 72.458 2.188 -10.002 1.00 15.68 ? 292 LEU A N 1 ATOM 2198 C CA . LEU A 1 290 ? 72.571 1.723 -8.620 1.00 15.27 ? 292 LEU A CA 1 ATOM 2199 C C . LEU A 1 290 ? 72.085 0.285 -8.481 1.00 15.08 ? 292 LEU A C 1 ATOM 2200 O O . LEU A 1 290 ? 72.630 -0.492 -7.696 1.00 15.39 ? 292 LEU A O 1 ATOM 2201 C CB . LEU A 1 290 ? 71.790 2.641 -7.678 1.00 14.98 ? 292 LEU A CB 1 ATOM 2202 C CG . LEU A 1 290 ? 71.907 2.369 -6.175 1.00 15.18 ? 292 LEU A CG 1 ATOM 2203 C CD1 . LEU A 1 290 ? 73.309 2.686 -5.680 1.00 15.33 ? 292 LEU A CD1 1 ATOM 2204 C CD2 . LEU A 1 290 ? 70.874 3.176 -5.402 1.00 14.96 ? 292 LEU A CD2 1 ATOM 2205 N N . GLY A 1 291 ? 71.080 -0.073 -9.273 1.00 14.73 ? 293 GLY A N 1 ATOM 2206 C CA . GLY A 1 291 ? 70.416 -1.366 -9.149 1.00 13.29 ? 293 GLY A CA 1 ATOM 2207 C C . GLY A 1 291 ? 71.207 -2.550 -9.678 1.00 13.68 ? 293 GLY A C 1 ATOM 2208 O O . GLY A 1 291 ? 70.926 -3.696 -9.323 1.00 12.67 ? 293 GLY A O 1 ATOM 2209 N N . SER A 1 292 ? 72.196 -2.285 -10.529 1.00 14.07 ? 294 SER A N 1 ATOM 2210 C CA . SER A 1 292 ? 72.928 -3.364 -11.192 1.00 14.00 ? 294 SER A CA 1 ATOM 2211 C C . SER A 1 292 ? 74.446 -3.267 -11.044 1.00 13.35 ? 294 SER A C 1 ATOM 2212 O O . SER A 1 292 ? 75.161 -4.238 -11.286 1.00 13.68 ? 294 SER A O 1 ATOM 2213 C CB . SER A 1 292 ? 72.545 -3.449 -12.673 1.00 14.88 ? 294 SER A CB 1 ATOM 2214 O OG . SER A 1 292 ? 72.963 -2.292 -13.370 1.00 14.97 ? 294 SER A OG 1 ATOM 2215 N N . ASP A 1 293 ? 74.941 -2.092 -10.672 1.00 12.97 ? 295 ASP A N 1 ATOM 2216 C CA . ASP A 1 293 ? 76.379 -1.855 -10.660 1.00 12.49 ? 295 ASP A CA 1 ATOM 2217 C C . ASP A 1 293 ? 77.020 -2.405 -9.389 1.00 12.21 ? 295 ASP A C 1 ATOM 2218 O O . ASP A 1 293 ? 76.790 -1.892 -8.298 1.00 11.30 ? 295 ASP A O 1 ATOM 2219 C CB . ASP A 1 293 ? 76.683 -0.360 -10.794 1.00 13.01 ? 295 ASP A CB 1 ATOM 2220 C CG . ASP A 1 293 ? 78.160 -0.049 -10.625 1.00 13.57 ? 295 ASP A CG 1 ATOM 2221 O OD1 . ASP A 1 293 ? 78.993 -0.815 -11.153 1.00 14.19 ? 295 ASP A OD1 1 ATOM 2222 O OD2 . ASP A 1 293 ? 78.490 0.950 -9.948 1.00 14.37 ? 295 ASP A OD2 1 ATOM 2223 N N . GLN A 1 294 ? 77.824 -3.452 -9.537 1.00 11.27 ? 296 GLN A N 1 ATOM 2224 C CA . GLN A 1 294 ? 78.573 -3.996 -8.412 1.00 11.56 ? 296 GLN A CA 1 ATOM 2225 C C . GLN A 1 294 ? 80.071 -3.831 -8.609 1.00 11.70 ? 296 GLN A C 1 ATOM 2226 O O . GLN A 1 294 ? 80.868 -4.477 -7.926 1.00 11.32 ? 296 GLN A O 1 ATOM 2227 C CB . GLN A 1 294 ? 78.225 -5.469 -8.195 1.00 10.92 ? 296 GLN A CB 1 ATOM 2228 C CG . GLN A 1 294 ? 76.779 -5.677 -7.773 1.00 10.71 ? 296 GLN A CG 1 ATOM 2229 C CD . GLN A 1 294 ? 76.490 -7.095 -7.337 1.00 10.93 ? 296 GLN A CD 1 ATOM 2230 O OE1 . GLN A 1 294 ? 76.803 -7.486 -6.209 1.00 10.96 ? 296 GLN A OE1 1 ATOM 2231 N NE2 . GLN A 1 294 ? 75.808 -7.847 -8.194 1.00 11.62 ? 296 GLN A NE2 1 ATOM 2232 N N . SER A 1 295 ? 80.451 -2.967 -9.547 1.00 11.67 ? 297 SER A N 1 ATOM 2233 C CA . SER A 1 295 ? 81.861 -2.785 -9.885 1.00 12.37 ? 297 SER A CA 1 ATOM 2234 C C . SER A 1 295 ? 82.611 -1.992 -8.817 1.00 12.81 ? 297 SER A C 1 ATOM 2235 O O . SER A 1 295 ? 83.830 -2.106 -8.687 1.00 12.97 ? 297 SER A O 1 ATOM 2236 C CB . SER A 1 295 ? 82.010 -2.109 -11.249 1.00 12.89 ? 297 SER A CB 1 ATOM 2237 O OG . SER A 1 295 ? 81.659 -0.739 -11.179 1.00 13.05 ? 297 SER A OG 1 ATOM 2238 N N . HIS A 1 296 ? 81.884 -1.189 -8.048 1.00 12.57 ? 298 HIS A N 1 ATOM 2239 C CA . HIS A 1 296 ? 82.503 -0.430 -6.966 1.00 12.66 ? 298 HIS A CA 1 ATOM 2240 C C . HIS A 1 296 ? 82.468 -1.218 -5.657 1.00 12.11 ? 298 HIS A C 1 ATOM 2241 O O . HIS A 1 296 ? 83.466 -1.297 -4.940 1.00 11.95 ? 298 HIS A O 1 ATOM 2242 C CB . HIS A 1 296 ? 81.816 0.928 -6.800 1.00 12.55 ? 298 HIS A CB 1 ATOM 2243 C CG . HIS A 1 296 ? 81.949 1.820 -7.997 1.00 13.26 ? 298 HIS A CG 1 ATOM 2244 N ND1 . HIS A 1 296 ? 81.099 1.746 -9.079 1.00 13.79 ? 298 HIS A ND1 1 ATOM 2245 C CD2 . HIS A 1 296 ? 82.827 2.814 -8.276 1.00 13.95 ? 298 HIS A CD2 1 ATOM 2246 C CE1 . HIS A 1 296 ? 81.453 2.647 -9.979 1.00 14.19 ? 298 HIS A CE1 1 ATOM 2247 N NE2 . HIS A 1 296 ? 82.497 3.311 -9.515 1.00 14.44 ? 298 HIS A NE2 1 ATOM 2248 N N . CYS A 1 297 ? 81.321 -1.823 -5.370 1.00 11.68 ? 299 CYS A N 1 ATOM 2249 C CA . CYS A 1 297 ? 81.141 -2.614 -4.156 1.00 11.45 ? 299 CYS A CA 1 ATOM 2250 C C . CYS A 1 297 ? 80.007 -3.614 -4.372 1.00 11.42 ? 299 CYS A C 1 ATOM 2251 O O . CYS A 1 297 ? 78.929 -3.239 -4.833 1.00 11.57 ? 299 CYS A O 1 ATOM 2252 C CB . CYS A 1 297 ? 80.828 -1.700 -2.965 1.00 11.07 ? 299 CYS A CB 1 ATOM 2253 S SG . CYS A 1 297 ? 80.608 -2.543 -1.374 1.00 11.31 ? 299 CYS A SG 1 ATOM 2254 N N . PRO A 1 298 ? 80.262 -4.900 -4.083 1.00 11.44 ? 300 PRO A N 1 ATOM 2255 C CA . PRO A 1 298 ? 79.218 -5.917 -4.203 1.00 10.95 ? 300 PRO A CA 1 ATOM 2256 C C . PRO A 1 298 ? 78.003 -5.548 -3.362 1.00 10.73 ? 300 PRO A C 1 ATOM 2257 O O . PRO A 1 298 ? 78.154 -4.999 -2.269 1.00 10.50 ? 300 PRO A O 1 ATOM 2258 C CB . PRO A 1 298 ? 79.880 -7.172 -3.625 1.00 11.54 ? 300 PRO A CB 1 ATOM 2259 C CG . PRO A 1 298 ? 81.348 -6.933 -3.766 1.00 11.84 ? 300 PRO A CG 1 ATOM 2260 C CD . PRO A 1 298 ? 81.532 -5.457 -3.587 1.00 11.10 ? 300 PRO A CD 1 ATOM 2261 N N . PHE A 1 299 ? 76.810 -5.887 -3.842 1.00 10.49 ? 301 PHE A N 1 ATOM 2262 C CA . PHE A 1 299 ? 75.605 -5.728 -3.033 1.00 10.23 ? 301 PHE A CA 1 ATOM 2263 C C . PHE A 1 299 ? 75.706 -6.561 -1.754 1.00 10.09 ? 301 PHE A C 1 ATOM 2264 O O . PHE A 1 299 ? 75.039 -6.277 -0.760 1.00 9.90 ? 301 PHE A O 1 ATOM 2265 C CB . PHE A 1 299 ? 74.358 -6.126 -3.831 1.00 10.02 ? 301 PHE A CB 1 ATOM 2266 C CG . PHE A 1 299 ? 74.175 -5.347 -5.108 1.00 10.07 ? 301 PHE A CG 1 ATOM 2267 C CD1 . PHE A 1 299 ? 74.504 -4.002 -5.171 1.00 9.99 ? 301 PHE A CD1 1 ATOM 2268 C CD2 . PHE A 1 299 ? 73.633 -5.951 -6.230 1.00 10.14 ? 301 PHE A CD2 1 ATOM 2269 C CE1 . PHE A 1 299 ? 74.336 -3.286 -6.345 1.00 10.44 ? 301 PHE A CE1 1 ATOM 2270 C CE2 . PHE A 1 299 ? 73.455 -5.240 -7.405 1.00 10.13 ? 301 PHE A CE2 1 ATOM 2271 C CZ . PHE A 1 299 ? 73.801 -3.904 -7.461 1.00 10.02 ? 301 PHE A CZ 1 ATOM 2272 N N . SER A 1 300 ? 76.590 -7.553 -1.768 1.00 9.81 ? 302 SER A N 1 ATOM 2273 C CA . SER A 1 300 ? 76.662 -8.536 -0.693 1.00 9.61 ? 302 SER A CA 1 ATOM 2274 C C . SER A 1 300 ? 77.730 -8.231 0.360 1.00 8.92 ? 302 SER A C 1 ATOM 2275 O O . SER A 1 300 ? 77.851 -8.948 1.351 1.00 8.76 ? 302 SER A O 1 ATOM 2276 C CB . SER A 1 300 ? 76.892 -9.932 -1.272 1.00 9.61 ? 302 SER A CB 1 ATOM 2277 O OG . SER A 1 300 ? 77.936 -9.913 -2.227 1.00 10.17 ? 302 SER A OG 1 ATOM 2278 N N . ALA A 1 301 ? 78.530 -7.195 0.129 1.00 9.22 ? 303 ALA A N 1 ATOM 2279 C CA . ALA A 1 301 ? 79.596 -6.836 1.064 1.00 8.69 ? 303 ALA A CA 1 ATOM 2280 C C . ALA A 1 301 ? 79.058 -6.588 2.478 1.00 8.65 ? 303 ALA A C 1 ATOM 2281 O O . ALA A 1 301 ? 77.969 -6.028 2.639 1.00 8.67 ? 303 ALA A O 1 ATOM 2282 C CB . ALA A 1 301 ? 80.349 -5.614 0.554 1.00 8.81 ? 303 ALA A CB 1 ATOM 2283 N N . HIS A 1 302 ? 79.824 -6.998 3.493 1.00 8.42 ? 304 HIS A N 1 ATOM 2284 C CA . HIS A 1 302 ? 79.410 -6.876 4.911 1.00 8.21 ? 304 HIS A CA 1 ATOM 2285 C C . HIS A 1 302 ? 78.804 -5.511 5.229 1.00 7.80 ? 304 HIS A C 1 ATOM 2286 O O . HIS A 1 302 ? 77.681 -5.428 5.714 1.00 7.55 ? 304 HIS A O 1 ATOM 2287 C CB . HIS A 1 302 ? 80.585 -7.178 5.862 1.00 8.37 ? 304 HIS A CB 1 ATOM 2288 C CG . HIS A 1 302 ? 80.285 -6.965 7.326 1.00 8.60 ? 304 HIS A CG 1 ATOM 2289 N ND1 . HIS A 1 302 ? 79.254 -7.605 7.979 1.00 8.80 ? 304 HIS A ND1 1 ATOM 2290 C CD2 . HIS A 1 302 ? 80.966 -6.287 8.285 1.00 8.89 ? 304 HIS A CD2 1 ATOM 2291 C CE1 . HIS A 1 302 ? 79.275 -7.281 9.264 1.00 8.88 ? 304 HIS A CE1 1 ATOM 2292 N NE2 . HIS A 1 302 ? 80.312 -6.490 9.480 1.00 8.95 ? 304 HIS A NE2 1 ATOM 2293 N N . ILE A 1 303 ? 79.555 -4.440 4.996 1.00 7.58 ? 305 ILE A N 1 ATOM 2294 C CA . ILE A 1 303 ? 79.090 -3.122 5.419 1.00 7.57 ? 305 ILE A CA 1 ATOM 2295 C C . ILE A 1 303 ? 77.879 -2.631 4.627 1.00 8.12 ? 305 ILE A C 1 ATOM 2296 O O . ILE A 1 303 ? 77.066 -1.859 5.142 1.00 8.19 ? 305 ILE A O 1 ATOM 2297 C CB . ILE A 1 303 ? 80.211 -2.059 5.428 1.00 7.57 ? 305 ILE A CB 1 ATOM 2298 C CG1 . ILE A 1 303 ? 80.733 -1.784 4.015 1.00 7.78 ? 305 ILE A CG1 1 ATOM 2299 C CG2 . ILE A 1 303 ? 81.336 -2.467 6.367 1.00 7.16 ? 305 ILE A CG2 1 ATOM 2300 C CD1 . ILE A 1 303 ? 81.457 -0.458 3.902 1.00 7.54 ? 305 ILE A CD1 1 ATOM 2301 N N . ARG A 1 304 ? 77.738 -3.113 3.395 1.00 8.30 ? 306 ARG A N 1 ATOM 2302 C CA . ARG A 1 304 ? 76.588 -2.762 2.564 1.00 8.67 ? 306 ARG A CA 1 ATOM 2303 C C . ARG A 1 304 ? 75.343 -3.519 3.021 1.00 8.98 ? 306 ARG A C 1 ATOM 2304 O O . ARG A 1 304 ? 74.230 -2.995 2.975 1.00 9.02 ? 306 ARG A O 1 ATOM 2305 C CB . ARG A 1 304 ? 76.883 -3.057 1.087 1.00 9.07 ? 306 ARG A CB 1 ATOM 2306 C CG . ARG A 1 304 ? 75.844 -2.507 0.120 1.00 9.40 ? 306 ARG A CG 1 ATOM 2307 C CD . ARG A 1 304 ? 76.416 -2.354 -1.285 1.00 10.20 ? 306 ARG A CD 1 ATOM 2308 N NE . ARG A 1 304 ? 75.490 -1.660 -2.174 1.00 10.21 ? 306 ARG A NE 1 ATOM 2309 C CZ . ARG A 1 304 ? 75.804 -1.205 -3.383 1.00 10.39 ? 306 ARG A CZ 1 ATOM 2310 N NH1 . ARG A 1 304 ? 77.024 -1.384 -3.871 1.00 10.85 ? 306 ARG A NH1 1 ATOM 2311 N NH2 . ARG A 1 304 ? 74.897 -0.561 -4.104 1.00 10.39 ? 306 ARG A NH2 1 ATOM 2312 N N . LYS A 1 305 ? 75.548 -4.738 3.510 1.00 8.87 ? 307 LYS A N 1 ATOM 2313 C CA . LYS A 1 305 ? 74.457 -5.536 4.063 1.00 9.28 ? 307 LYS A CA 1 ATOM 2314 C C . LYS A 1 305 ? 73.946 -4.956 5.379 1.00 9.71 ? 307 LYS A C 1 ATOM 2315 O O . LYS A 1 305 ? 72.754 -5.047 5.678 1.00 10.92 ? 307 LYS A O 1 ATOM 2316 C CB . LYS A 1 305 ? 74.907 -6.984 4.274 1.00 8.88 ? 307 LYS A CB 1 ATOM 2317 C CG . LYS A 1 305 ? 74.900 -7.822 3.006 1.00 8.95 ? 307 LYS A CG 1 ATOM 2318 C CD . LYS A 1 305 ? 73.508 -8.363 2.714 1.00 8.91 ? 307 LYS A CD 1 ATOM 2319 C CE . LYS A 1 305 ? 73.574 -9.677 1.951 1.00 9.18 ? 307 LYS A CE 1 ATOM 2320 N NZ . LYS A 1 305 ? 72.243 -10.340 1.881 1.00 9.61 ? 307 LYS A NZ 1 ATOM 2321 N N . THR A 1 306 ? 74.847 -4.380 6.171 1.00 8.61 ? 308 THR A N 1 ATOM 2322 C CA . THR A 1 306 ? 74.496 -3.943 7.519 1.00 8.45 ? 308 THR A CA 1 ATOM 2323 C C . THR A 1 306 ? 74.158 -2.455 7.620 1.00 8.54 ? 308 THR A C 1 ATOM 2324 O O . THR A 1 306 ? 73.479 -2.039 8.559 1.00 8.53 ? 308 THR A O 1 ATOM 2325 C CB . THR A 1 306 ? 75.580 -4.303 8.547 1.00 8.12 ? 308 THR A CB 1 ATOM 2326 O OG1 . THR A 1 306 ? 76.836 -3.756 8.131 1.00 8.51 ? 308 THR A OG1 1 ATOM 2327 C CG2 . THR A 1 306 ? 75.705 -5.820 8.675 1.00 8.12 ? 308 THR A CG2 1 ATOM 2328 N N . ARG A 1 307 ? 74.663 -1.659 6.681 1.00 8.44 ? 309 ARG A N 1 ATOM 2329 C CA . ARG A 1 307 ? 74.128 -0.312 6.439 1.00 8.74 ? 309 ARG A CA 1 ATOM 2330 C C . ARG A 1 307 ? 73.977 -0.046 4.941 1.00 8.97 ? 309 ARG A C 1 ATOM 2331 O O . ARG A 1 307 ? 74.950 0.278 4.261 1.00 9.91 ? 309 ARG A O 1 ATOM 2332 C CB . ARG A 1 307 ? 74.994 0.773 7.094 1.00 8.90 ? 309 ARG A CB 1 ATOM 2333 C CG . ARG A 1 307 ? 74.358 2.163 7.040 1.00 8.78 ? 309 ARG A CG 1 ATOM 2334 C CD . ARG A 1 307 ? 75.361 3.305 7.170 1.00 8.80 ? 309 ARG A CD 1 ATOM 2335 N NE . ARG A 1 307 ? 74.742 4.579 6.797 1.00 9.06 ? 309 ARG A NE 1 ATOM 2336 C CZ . ARG A 1 307 ? 75.399 5.719 6.594 1.00 9.12 ? 309 ARG A CZ 1 ATOM 2337 N NH1 . ARG A 1 307 ? 76.701 5.796 6.824 1.00 8.91 ? 309 ARG A NH1 1 ATOM 2338 N NH2 . ARG A 1 307 ? 74.738 6.800 6.192 1.00 9.37 ? 309 ARG A NH2 1 ATOM 2339 N N . PRO A 1 308 ? 72.757 -0.225 4.418 1.00 8.97 ? 310 PRO A N 1 ATOM 2340 C CA . PRO A 1 308 ? 72.503 -0.242 2.976 1.00 9.08 ? 310 PRO A CA 1 ATOM 2341 C C . PRO A 1 308 ? 72.683 1.118 2.305 1.00 9.21 ? 310 PRO A C 1 ATOM 2342 O O . PRO A 1 308 ? 72.852 1.187 1.086 1.00 9.37 ? 310 PRO A O 1 ATOM 2343 C CB . PRO A 1 308 ? 71.037 -0.676 2.883 1.00 9.49 ? 310 PRO A CB 1 ATOM 2344 C CG . PRO A 1 308 ? 70.783 -1.426 4.148 1.00 9.96 ? 310 PRO A CG 1 ATOM 2345 C CD . PRO A 1 308 ? 71.613 -0.739 5.190 1.00 9.27 ? 310 PRO A CD 1 ATOM 2346 N N . ARG A 1 309 ? 72.596 2.188 3.089 1.00 9.09 ? 311 ARG A N 1 ATOM 2347 C CA . ARG A 1 309 ? 72.638 3.544 2.551 1.00 9.44 ? 311 ARG A CA 1 ATOM 2348 C C . ARG A 1 309 ? 71.665 3.720 1.380 1.00 10.00 ? 311 ARG A C 1 ATOM 2349 O O . ARG A 1 309 ? 70.470 3.452 1.521 1.00 10.05 ? 311 ARG A O 1 ATOM 2350 C CB . ARG A 1 309 ? 74.080 3.942 2.189 1.00 9.49 ? 311 ARG A CB 1 ATOM 2351 C CG . ARG A 1 309 ? 75.054 3.712 3.341 1.00 9.36 ? 311 ARG A CG 1 ATOM 2352 C CD . ARG A 1 309 ? 76.476 4.192 3.064 1.00 9.02 ? 311 ARG A CD 1 ATOM 2353 N NE . ARG A 1 309 ? 77.388 3.663 4.077 1.00 9.41 ? 311 ARG A NE 1 ATOM 2354 C CZ . ARG A 1 309 ? 78.419 4.321 4.599 1.00 9.31 ? 311 ARG A CZ 1 ATOM 2355 N NH1 . ARG A 1 309 ? 78.727 5.542 4.177 1.00 8.80 ? 311 ARG A NH1 1 ATOM 2356 N NH2 . ARG A 1 309 ? 79.154 3.749 5.544 1.00 9.51 ? 311 ARG A NH2 1 ATOM 2357 N N . ALA A 1 310 ? 72.162 4.173 0.233 1.00 10.14 ? 312 ALA A N 1 ATOM 2358 C CA . ALA A 1 310 ? 71.279 4.501 -0.890 1.00 10.63 ? 312 ALA A CA 1 ATOM 2359 C C . ALA A 1 310 ? 70.484 3.302 -1.407 1.00 10.95 ? 312 ALA A C 1 ATOM 2360 O O . ALA A 1 310 ? 69.527 3.469 -2.163 1.00 10.29 ? 312 ALA A O 1 ATOM 2361 C CB . ALA A 1 310 ? 72.060 5.150 -2.024 1.00 10.42 ? 312 ALA A CB 1 ATOM 2362 N N . ASP A 1 311 ? 70.882 2.095 -1.009 1.00 11.25 ? 313 ASP A N 1 ATOM 2363 C CA . ASP A 1 311 ? 70.167 0.888 -1.428 1.00 11.53 ? 313 ASP A CA 1 ATOM 2364 C C . ASP A 1 311 ? 68.736 0.876 -0.900 1.00 12.24 ? 313 ASP A C 1 ATOM 2365 O O . ASP A 1 311 ? 67.866 0.207 -1.458 1.00 12.82 ? 313 ASP A O 1 ATOM 2366 C CB . ASP A 1 311 ? 70.899 -0.376 -0.964 1.00 11.29 ? 313 ASP A CB 1 ATOM 2367 C CG . ASP A 1 311 ? 72.073 -0.734 -1.856 1.00 12.53 ? 313 ASP A CG 1 ATOM 2368 O OD1 . ASP A 1 311 ? 72.201 -0.145 -2.955 1.00 12.74 ? 313 ASP A OD1 1 ATOM 2369 O OD2 . ASP A 1 311 ? 72.864 -1.620 -1.460 1.00 12.79 ? 313 ASP A OD2 1 ATOM 2370 N N . LEU A 1 312 ? 68.502 1.589 0.196 1.00 12.54 ? 314 LEU A N 1 ATOM 2371 C CA . LEU A 1 312 ? 67.152 1.714 0.741 1.00 13.25 ? 314 LEU A CA 1 ATOM 2372 C C . LEU A 1 312 ? 66.586 3.106 0.497 1.00 13.50 ? 314 LEU A C 1 ATOM 2373 O O . LEU A 1 312 ? 65.740 3.582 1.252 1.00 14.27 ? 314 LEU A O 1 ATOM 2374 C CB . LEU A 1 312 ? 67.124 1.375 2.234 1.00 13.51 ? 314 LEU A CB 1 ATOM 2375 C CG . LEU A 1 312 ? 67.226 -0.115 2.582 1.00 13.97 ? 314 LEU A CG 1 ATOM 2376 C CD1 . LEU A 1 312 ? 67.100 -0.340 4.084 1.00 14.11 ? 314 LEU A CD1 1 ATOM 2377 C CD2 . LEU A 1 312 ? 66.173 -0.918 1.835 1.00 14.10 ? 314 LEU A CD2 1 ATOM 2378 N N . GLY A 1 313 ? 67.064 3.752 -0.562 1.00 13.65 ? 315 GLY A N 1 ATOM 2379 C CA . GLY A 1 313 ? 66.528 5.037 -0.991 1.00 14.77 ? 315 GLY A CA 1 ATOM 2380 C C . GLY A 1 313 ? 67.198 6.215 -0.312 1.00 14.47 ? 315 GLY A C 1 ATOM 2381 O O . GLY A 1 313 ? 68.236 6.068 0.336 1.00 14.56 ? 315 GLY A O 1 ATOM 2382 N N . GLY A 1 314 ? 66.596 7.391 -0.454 1.00 13.94 ? 316 GLY A N 1 ATOM 2383 C CA . GLY A 1 314 ? 67.150 8.601 0.135 1.00 13.52 ? 316 GLY A CA 1 ATOM 2384 C C . GLY A 1 314 ? 68.178 9.260 -0.763 1.00 13.75 ? 316 GLY A C 1 ATOM 2385 O O . GLY A 1 314 ? 68.181 9.055 -1.977 1.00 13.28 ? 316 GLY A O 1 ATOM 2386 N N . SER A 1 315 ? 69.051 10.060 -0.163 1.00 13.21 ? 317 SER A N 1 ATOM 2387 C CA . SER A 1 315 ? 69.983 10.885 -0.921 1.00 14.37 ? 317 SER A CA 1 ATOM 2388 C C . SER A 1 315 ? 71.060 10.049 -1.607 1.00 14.62 ? 317 SER A C 1 ATOM 2389 O O . SER A 1 315 ? 71.633 9.140 -1.006 1.00 13.76 ? 317 SER A O 1 ATOM 2390 C CB . SER A 1 315 ? 70.632 11.924 -0.009 1.00 14.83 ? 317 SER A CB 1 ATOM 2391 O OG . SER A 1 315 ? 71.480 12.785 -0.746 1.00 16.20 ? 317 SER A OG 1 ATOM 2392 N N . LEU A 1 316 ? 71.349 10.382 -2.861 1.00 15.06 ? 318 LEU A N 1 ATOM 2393 C CA . LEU A 1 316 ? 72.437 9.745 -3.594 1.00 15.35 ? 318 LEU A CA 1 ATOM 2394 C C . LEU A 1 316 ? 73.770 10.429 -3.308 1.00 15.36 ? 318 LEU A C 1 ATOM 2395 O O . LEU A 1 316 ? 74.834 9.849 -3.528 1.00 15.54 ? 318 LEU A O 1 ATOM 2396 C CB . LEU A 1 316 ? 72.145 9.752 -5.100 1.00 16.21 ? 318 LEU A CB 1 ATOM 2397 C CG . LEU A 1 316 ? 70.829 9.098 -5.528 1.00 17.18 ? 318 LEU A CG 1 ATOM 2398 C CD1 . LEU A 1 316 ? 70.750 8.964 -7.041 1.00 17.95 ? 318 LEU A CD1 1 ATOM 2399 C CD2 . LEU A 1 316 ? 70.653 7.745 -4.861 1.00 17.90 ? 318 LEU A CD2 1 ATOM 2400 N N . THR A 1 317 ? 73.709 11.651 -2.788 1.00 15.20 ? 319 THR A N 1 ATOM 2401 C CA . THR A 1 317 ? 74.906 12.335 -2.304 1.00 16.04 ? 319 THR A CA 1 ATOM 2402 C C . THR A 1 317 ? 74.980 12.282 -0.781 1.00 16.27 ? 319 THR A C 1 ATOM 2403 O O . THR A 1 317 ? 73.952 12.297 -0.104 1.00 17.05 ? 319 THR A O 1 ATOM 2404 C CB . THR A 1 317 ? 74.943 13.811 -2.755 1.00 17.26 ? 319 THR A CB 1 ATOM 2405 O OG1 . THR A 1 317 ? 73.814 14.504 -2.211 1.00 16.97 ? 319 THR A OG1 1 ATOM 2406 C CG2 . THR A 1 317 ? 74.907 13.908 -4.273 1.00 17.36 ? 319 THR A CG2 1 ATOM 2407 N N . PRO A 1 318 ? 76.201 12.213 -0.234 1.00 16.51 ? 320 PRO A N 1 ATOM 2408 C CA . PRO A 1 318 ? 76.377 12.109 1.213 1.00 16.86 ? 320 PRO A CA 1 ATOM 2409 C C . PRO A 1 318 ? 75.891 13.373 1.918 1.00 17.32 ? 320 PRO A C 1 ATOM 2410 O O . PRO A 1 318 ? 76.097 14.478 1.416 1.00 16.92 ? 320 PRO A O 1 ATOM 2411 C CB . PRO A 1 318 ? 77.896 11.961 1.378 1.00 17.27 ? 320 PRO A CB 1 ATOM 2412 C CG . PRO A 1 318 ? 78.409 11.570 0.031 1.00 16.74 ? 320 PRO A CG 1 ATOM 2413 C CD . PRO A 1 318 ? 77.487 12.229 -0.948 1.00 16.34 ? 320 PRO A CD 1 ATOM 2414 N N . PRO A 1 319 ? 75.261 13.210 3.077 1.00 17.06 ? 321 PRO A N 1 ATOM 2415 C CA . PRO A 1 319 ? 75.121 11.905 3.704 1.00 16.32 ? 321 PRO A CA 1 ATOM 2416 C C . PRO A 1 319 ? 73.785 11.258 3.358 1.00 15.81 ? 321 PRO A C 1 ATOM 2417 O O . PRO A 1 319 ? 72.750 11.925 3.370 1.00 15.63 ? 321 PRO A O 1 ATOM 2418 C CB . PRO A 1 319 ? 75.161 12.240 5.195 1.00 16.72 ? 321 PRO A CB 1 ATOM 2419 C CG . PRO A 1 319 ? 74.553 13.601 5.278 1.00 16.63 ? 321 PRO A CG 1 ATOM 2420 C CD . PRO A 1 319 ? 74.905 14.310 3.994 1.00 17.01 ? 321 PRO A CD 1 ATOM 2421 N N . ASN A 1 320 ? 73.809 9.962 3.065 1.00 13.49 ? 322 ASN A N 1 ATOM 2422 C CA . ASN A 1 320 ? 72.578 9.194 2.982 1.00 12.22 ? 322 ASN A CA 1 ATOM 2423 C C . ASN A 1 320 ? 72.048 8.866 4.375 1.00 12.29 ? 322 ASN A C 1 ATOM 2424 O O . ASN A 1 320 ? 72.816 8.514 5.270 1.00 11.61 ? 322 ASN A O 1 ATOM 2425 C CB . ASN A 1 320 ? 72.790 7.911 2.177 1.00 11.60 ? 322 ASN A CB 1 ATOM 2426 C CG . ASN A 1 320 ? 71.531 7.069 2.089 1.00 11.83 ? 322 ASN A CG 1 ATOM 2427 O OD1 . ASN A 1 320 ? 71.228 6.293 2.995 1.00 11.98 ? 322 ASN A OD1 1 ATOM 2428 N ND2 . ASN A 1 320 ? 70.770 7.249 1.017 1.00 12.17 ? 322 ASN A ND2 1 ATOM 2429 N N . LEU A 1 321 ? 70.735 8.982 4.553 1.00 12.28 ? 323 LEU A N 1 ATOM 2430 C CA . LEU A 1 321 ? 70.141 8.934 5.890 1.00 12.46 ? 323 LEU A CA 1 ATOM 2431 C C . LEU A 1 321 ? 69.121 7.809 6.056 1.00 12.43 ? 323 LEU A C 1 ATOM 2432 O O . LEU A 1 321 ? 68.355 7.797 7.023 1.00 11.62 ? 323 LEU A O 1 ATOM 2433 C CB . LEU A 1 321 ? 69.495 10.277 6.238 1.00 12.90 ? 323 LEU A CB 1 ATOM 2434 C CG . LEU A 1 321 ? 70.437 11.478 6.349 1.00 13.34 ? 323 LEU A CG 1 ATOM 2435 C CD1 . LEU A 1 321 ? 69.651 12.748 6.646 1.00 14.41 ? 323 LEU A CD1 1 ATOM 2436 C CD2 . LEU A 1 321 ? 71.493 11.228 7.416 1.00 13.44 ? 323 LEU A CD2 1 ATOM 2437 N N . SER A 1 322 ? 69.146 6.845 5.140 1.00 11.72 ? 324 SER A N 1 ATOM 2438 C CA . SER A 1 322 ? 68.167 5.759 5.136 1.00 11.38 ? 324 SER A CA 1 ATOM 2439 C C . SER A 1 322 ? 68.298 4.856 6.359 1.00 12.05 ? 324 SER A C 1 ATOM 2440 O O . SER A 1 322 ? 69.393 4.684 6.901 1.00 12.55 ? 324 SER A O 1 ATOM 2441 C CB . SER A 1 322 ? 68.302 4.917 3.863 1.00 11.82 ? 324 SER A CB 1 ATOM 2442 O OG . SER A 1 322 ? 69.393 4.015 3.973 1.00 11.60 ? 324 SER A OG 1 ATOM 2443 N N . ALA A 1 323 ? 67.181 4.247 6.756 1.00 10.98 ? 325 ALA A N 1 ATOM 2444 C CA . ALA A 1 323 ? 67.186 3.143 7.713 1.00 11.34 ? 325 ALA A CA 1 ATOM 2445 C C . ALA A 1 323 ? 67.874 3.503 9.025 1.00 11.29 ? 325 ALA A C 1 ATOM 2446 O O . ALA A 1 323 ? 68.607 2.691 9.593 1.00 11.06 ? 325 ALA A O 1 ATOM 2447 C CB . ALA A 1 323 ? 67.830 1.905 7.099 1.00 11.00 ? 325 ALA A CB 1 ATOM 2448 N N . GLY A 1 324 ? 67.639 4.719 9.506 1.00 11.42 ? 326 GLY A N 1 ATOM 2449 C CA . GLY A 1 324 ? 68.285 5.190 10.725 1.00 10.85 ? 326 GLY A CA 1 ATOM 2450 C C . GLY A 1 324 ? 67.860 4.390 11.938 1.00 11.55 ? 326 GLY A C 1 ATOM 2451 O O . GLY A 1 324 ? 68.644 4.181 12.867 1.00 11.57 ? 326 GLY A O 1 ATOM 2452 N N . ALA A 1 325 ? 66.617 3.921 11.921 1.00 11.55 ? 327 ALA A N 1 ATOM 2453 C CA . ALA A 1 325 ? 66.083 3.146 13.033 1.00 11.83 ? 327 ALA A CA 1 ATOM 2454 C C . ALA A 1 325 ? 66.739 1.770 13.125 1.00 11.73 ? 327 ALA A C 1 ATOM 2455 O O . ALA A 1 325 ? 66.623 1.091 14.145 1.00 11.38 ? 327 ALA A O 1 ATOM 2456 C CB . ALA A 1 325 ? 64.573 3.007 12.911 1.00 12.04 ? 327 ALA A CB 1 ATOM 2457 N N . ASN A 1 326 ? 67.409 1.355 12.054 1.00 11.59 ? 328 ASN A N 1 ATOM 2458 C CA . ASN A 1 326 ? 68.136 0.085 12.062 1.00 12.07 ? 328 ASN A CA 1 ATOM 2459 C C . ASN A 1 326 ? 69.631 0.232 12.359 1.00 12.37 ? 328 ASN A C 1 ATOM 2460 O O . ASN A 1 326 ? 70.436 -0.623 11.988 1.00 12.13 ? 328 ASN A O 1 ATOM 2461 C CB . ASN A 1 326 ? 67.910 -0.673 10.748 1.00 12.35 ? 328 ASN A CB 1 ATOM 2462 C CG . ASN A 1 326 ? 66.437 -0.903 10.455 1.00 12.99 ? 328 ASN A CG 1 ATOM 2463 O OD1 . ASN A 1 326 ? 65.893 -0.374 9.483 1.00 13.51 ? 328 ASN A OD1 1 ATOM 2464 N ND2 . ASN A 1 326 ? 65.778 -1.673 11.312 1.00 13.38 ? 328 ASN A ND2 1 ATOM 2465 N N . SER A 1 327 ? 69.995 1.311 13.045 1.00 11.58 ? 329 SER A N 1 ATOM 2466 C CA . SER A 1 327 ? 71.388 1.549 13.416 1.00 11.12 ? 329 SER A CA 1 ATOM 2467 C C . SER A 1 327 ? 71.751 0.867 14.735 1.00 10.59 ? 329 SER A C 1 ATOM 2468 O O . SER A 1 327 ? 70.915 0.746 15.628 1.00 10.85 ? 329 SER A O 1 ATOM 2469 C CB . SER A 1 327 ? 71.659 3.051 13.519 1.00 11.42 ? 329 SER A CB 1 ATOM 2470 O OG . SER A 1 327 ? 71.309 3.705 12.311 1.00 12.15 ? 329 SER A OG 1 ATOM 2471 N N . ILE A 1 328 ? 72.998 0.417 14.844 1.00 9.75 ? 330 ILE A N 1 ATOM 2472 C CA . ILE A 1 328 ? 73.544 -0.047 16.118 1.00 9.40 ? 330 ILE A CA 1 ATOM 2473 C C . ILE A 1 328 ? 74.841 0.693 16.442 1.00 9.41 ? 330 ILE A C 1 ATOM 2474 O O . ILE A 1 328 ? 75.584 1.074 15.538 1.00 8.80 ? 330 ILE A O 1 ATOM 2475 C CB . ILE A 1 328 ? 73.836 -1.560 16.086 1.00 9.20 ? 330 ILE A CB 1 ATOM 2476 C CG1 . ILE A 1 328 ? 74.791 -1.891 14.934 1.00 8.80 ? 330 ILE A CG1 1 ATOM 2477 C CG2 . ILE A 1 328 ? 72.541 -2.349 15.952 1.00 9.44 ? 330 ILE A CG2 1 ATOM 2478 C CD1 . ILE A 1 328 ? 75.316 -3.313 14.957 1.00 8.30 ? 330 ILE A CD1 1 ATOM 2479 N N . MET A 1 329 ? 75.103 0.905 17.731 1.00 9.64 ? 331 MET A N 1 ATOM 2480 C CA . MET A 1 329 ? 76.435 1.304 18.180 1.00 10.68 ? 331 MET A CA 1 ATOM 2481 C C . MET A 1 329 ? 77.267 0.058 18.467 1.00 10.17 ? 331 MET A C 1 ATOM 2482 O O . MET A 1 329 ? 76.812 -0.843 19.171 1.00 10.08 ? 331 MET A O 1 ATOM 2483 C CB . MET A 1 329 ? 76.346 2.159 19.446 1.00 11.85 ? 331 MET A CB 1 ATOM 2484 C CG . MET A 1 329 ? 75.759 3.544 19.229 1.00 12.90 ? 331 MET A CG 1 ATOM 2485 S SD . MET A 1 329 ? 76.872 4.680 18.375 1.00 14.83 ? 331 MET A SD 1 ATOM 2486 C CE . MET A 1 329 ? 78.457 4.227 19.069 1.00 15.32 ? 331 MET A CE 1 ATOM 2487 N N . ARG A 1 330 ? 78.470 -0.002 17.901 1.00 9.71 ? 332 ARG A N 1 ATOM 2488 C CA . ARG A 1 330 ? 79.326 -1.180 18.043 1.00 9.93 ? 332 ARG A CA 1 ATOM 2489 C C . ARG A 1 330 ? 80.493 -0.909 18.987 1.00 10.37 ? 332 ARG A C 1 ATOM 2490 O O . ARG A 1 330 ? 81.220 0.071 18.818 1.00 10.58 ? 332 ARG A O 1 ATOM 2491 C CB . ARG A 1 330 ? 79.848 -1.632 16.675 1.00 9.87 ? 332 ARG A CB 1 ATOM 2492 C CG . ARG A 1 330 ? 78.795 -2.310 15.809 1.00 9.64 ? 332 ARG A CG 1 ATOM 2493 C CD . ARG A 1 330 ? 79.319 -2.593 14.406 1.00 11.24 ? 332 ARG A CD 1 ATOM 2494 N NE . ARG A 1 330 ? 79.886 -1.393 13.798 1.00 10.28 ? 332 ARG A NE 1 ATOM 2495 C CZ . ARG A 1 330 ? 81.125 -1.306 13.328 1.00 10.77 ? 332 ARG A CZ 1 ATOM 2496 N NH1 . ARG A 1 330 ? 81.922 -2.364 13.350 1.00 11.63 ? 332 ARG A NH1 1 ATOM 2497 N NH2 . ARG A 1 330 ? 81.568 -0.156 12.841 1.00 11.20 ? 332 ARG A NH2 1 ATOM 2498 N N . SER A 1 331 ? 80.659 -1.765 19.991 1.00 10.67 ? 333 SER A N 1 ATOM 2499 C CA . SER A 1 331 ? 81.787 -1.638 20.911 1.00 11.21 ? 333 SER A CA 1 ATOM 2500 C C . SER A 1 331 ? 82.538 -2.954 21.054 1.00 10.77 ? 333 SER A C 1 ATOM 2501 O O . SER A 1 331 ? 83.009 -3.293 22.142 1.00 10.48 ? 333 SER A O 1 ATOM 2502 C CB . SER A 1 331 ? 81.318 -1.164 22.285 1.00 12.32 ? 333 SER A CB 1 ATOM 2503 O OG . SER A 1 331 ? 80.614 0.061 22.184 1.00 15.54 ? 333 SER A OG 1 ATOM 2504 N N . GLY A 1 332 ? 82.647 -3.689 19.954 1.00 10.35 ? 334 GLY A N 1 ATOM 2505 C CA . GLY A 1 332 ? 83.287 -5.001 19.976 1.00 10.47 ? 334 GLY A CA 1 ATOM 2506 C C . GLY A 1 332 ? 84.789 -4.884 20.128 1.00 10.61 ? 334 GLY A C 1 ATOM 2507 O O . GLY A 1 332 ? 85.366 -3.824 19.871 1.00 11.41 ? 334 GLY A O 1 ATOM 2508 N N . ILE A 1 333 ? 85.426 -5.979 20.531 1.00 10.14 ? 335 ILE A N 1 ATOM 2509 C CA . ILE A 1 333 ? 86.865 -5.988 20.754 1.00 10.06 ? 335 ILE A CA 1 ATOM 2510 C C . ILE A 1 333 ? 87.388 -7.401 20.533 1.00 9.57 ? 335 ILE A C 1 ATOM 2511 O O . ILE A 1 333 ? 86.704 -8.374 20.853 1.00 8.86 ? 335 ILE A O 1 ATOM 2512 C CB . ILE A 1 333 ? 87.217 -5.488 22.176 1.00 10.48 ? 335 ILE A CB 1 ATOM 2513 C CG1 . ILE A 1 333 ? 88.723 -5.567 22.427 1.00 10.98 ? 335 ILE A CG1 1 ATOM 2514 C CG2 . ILE A 1 333 ? 86.439 -6.258 23.233 1.00 10.41 ? 335 ILE A CG2 1 ATOM 2515 C CD1 . ILE A 1 333 ? 89.168 -4.858 23.690 1.00 12.29 ? 335 ILE A CD1 1 ATOM 2516 N N . PRO A 1 334 ? 88.552 -7.524 19.877 1.00 9.88 ? 336 PRO A N 1 ATOM 2517 C CA . PRO A 1 334 ? 89.020 -8.861 19.513 1.00 9.74 ? 336 PRO A CA 1 ATOM 2518 C C . PRO A 1 334 ? 89.411 -9.677 20.743 1.00 10.06 ? 336 PRO A C 1 ATOM 2519 O O . PRO A 1 334 ? 89.741 -9.105 21.782 1.00 10.26 ? 336 PRO A O 1 ATOM 2520 C CB . PRO A 1 334 ? 90.247 -8.577 18.639 1.00 9.68 ? 336 PRO A CB 1 ATOM 2521 C CG . PRO A 1 334 ? 90.004 -7.213 18.080 1.00 10.18 ? 336 PRO A CG 1 ATOM 2522 C CD . PRO A 1 334 ? 89.288 -6.463 19.168 1.00 10.78 ? 336 PRO A CD 1 ATOM 2523 N N . TYR A 1 335 ? 89.328 -11.002 20.641 1.00 10.07 ? 337 TYR A N 1 ATOM 2524 C CA . TYR A 1 335 ? 89.773 -11.874 21.727 1.00 9.94 ? 337 TYR A CA 1 ATOM 2525 C C . TYR A 1 335 ? 90.657 -12.999 21.206 1.00 9.83 ? 337 TYR A C 1 ATOM 2526 O O . TYR A 1 335 ? 90.673 -13.284 20.007 1.00 9.35 ? 337 TYR A O 1 ATOM 2527 C CB . TYR A 1 335 ? 88.582 -12.436 22.519 1.00 10.26 ? 337 TYR A CB 1 ATOM 2528 C CG . TYR A 1 335 ? 87.807 -13.536 21.817 1.00 10.53 ? 337 TYR A CG 1 ATOM 2529 C CD1 . TYR A 1 335 ? 86.717 -13.236 21.010 1.00 10.35 ? 337 TYR A CD1 1 ATOM 2530 C CD2 . TYR A 1 335 ? 88.128 -14.877 22.009 1.00 10.53 ? 337 TYR A CD2 1 ATOM 2531 C CE1 . TYR A 1 335 ? 85.998 -14.231 20.376 1.00 10.84 ? 337 TYR A CE1 1 ATOM 2532 C CE2 . TYR A 1 335 ? 87.416 -15.881 21.374 1.00 11.56 ? 337 TYR A CE2 1 ATOM 2533 C CZ . TYR A 1 335 ? 86.345 -15.551 20.563 1.00 11.52 ? 337 TYR A CZ 1 ATOM 2534 O OH . TYR A 1 335 ? 85.623 -16.538 19.929 1.00 11.89 ? 337 TYR A OH 1 ATOM 2535 N N . GLY A 1 336 ? 91.421 -13.608 22.107 1.00 9.61 ? 338 GLY A N 1 ATOM 2536 C CA . GLY A 1 336 ? 92.252 -14.751 21.752 1.00 9.33 ? 338 GLY A CA 1 ATOM 2537 C C . GLY A 1 336 ? 93.654 -14.369 21.321 1.00 9.93 ? 338 GLY A C 1 ATOM 2538 O O . GLY A 1 336 ? 93.968 -13.186 21.174 1.00 10.33 ? 338 GLY A O 1 ATOM 2539 N N . PRO A 1 337 ? 94.508 -15.377 21.095 1.00 10.19 ? 339 PRO A N 1 ATOM 2540 C CA . PRO A 1 337 ? 95.878 -15.122 20.680 1.00 10.63 ? 339 PRO A CA 1 ATOM 2541 C C . PRO A 1 337 ? 95.947 -14.713 19.215 1.00 10.71 ? 339 PRO A C 1 ATOM 2542 O O . PRO A 1 337 ? 95.049 -15.028 18.436 1.00 10.81 ? 339 PRO A O 1 ATOM 2543 C CB . PRO A 1 337 ? 96.553 -16.480 20.876 1.00 10.12 ? 339 PRO A CB 1 ATOM 2544 C CG . PRO A 1 337 ? 95.458 -17.463 20.644 1.00 10.36 ? 339 PRO A CG 1 ATOM 2545 C CD . PRO A 1 337 ? 94.216 -16.817 21.197 1.00 10.03 ? 339 PRO A CD 1 ATOM 2546 N N . GLU A 1 338 ? 97.011 -14.009 18.852 1.00 10.91 ? 340 GLU A N 1 ATOM 2547 C CA . GLU A 1 338 ? 97.350 -13.821 17.450 1.00 11.09 ? 340 GLU A CA 1 ATOM 2548 C C . GLU A 1 338 ? 97.497 -15.169 16.749 1.00 10.85 ? 340 GLU A C 1 ATOM 2549 O O . GLU A 1 338 ? 97.727 -16.192 17.394 1.00 10.24 ? 340 GLU A O 1 ATOM 2550 C CB . GLU A 1 338 ? 98.637 -13.009 17.331 1.00 11.59 ? 340 GLU A CB 1 ATOM 2551 C CG . GLU A 1 338 ? 98.485 -11.574 17.811 1.00 11.82 ? 340 GLU A CG 1 ATOM 2552 C CD . GLU A 1 338 ? 97.637 -10.741 16.868 1.00 12.44 ? 340 GLU A CD 1 ATOM 2553 O OE1 . GLU A 1 338 ? 98.049 -10.567 15.705 1.00 13.67 ? 340 GLU A OE1 1 ATOM 2554 O OE2 . GLU A 1 338 ? 96.553 -10.277 17.281 1.00 13.36 ? 340 GLU A OE2 1 ATOM 2555 N N . VAL A 1 339 ? 97.303 -15.176 15.433 1.00 10.58 ? 341 VAL A N 1 ATOM 2556 C CA . VAL A 1 339 ? 97.493 -16.384 14.644 1.00 9.88 ? 341 VAL A CA 1 ATOM 2557 C C . VAL A 1 339 ? 98.926 -16.892 14.801 1.00 10.26 ? 341 VAL A C 1 ATOM 2558 O O . VAL A 1 339 ? 99.887 -16.137 14.634 1.00 9.50 ? 341 VAL A O 1 ATOM 2559 C CB . VAL A 1 339 ? 97.210 -16.132 13.148 1.00 9.92 ? 341 VAL A CB 1 ATOM 2560 C CG1 . VAL A 1 339 ? 97.422 -17.410 12.351 1.00 9.87 ? 341 VAL A CG1 1 ATOM 2561 C CG2 . VAL A 1 339 ? 95.793 -15.606 12.956 1.00 10.31 ? 341 VAL A CG2 1 ATOM 2562 N N . THR A 1 340 ? 99.064 -18.166 15.149 1.00 10.51 ? 342 THR A N 1 ATOM 2563 C CA . THR A 1 340 ? 100.383 -18.756 15.354 1.00 11.22 ? 342 THR A CA 1 ATOM 2564 C C . THR A 1 340 ? 100.995 -19.236 14.043 1.00 12.52 ? 342 THR A C 1 ATOM 2565 O O . THR A 1 340 ? 100.298 -19.380 13.037 1.00 12.17 ? 342 THR A O 1 ATOM 2566 C CB . THR A 1 340 ? 100.330 -19.926 16.347 1.00 11.17 ? 342 THR A CB 1 ATOM 2567 O OG1 . THR A 1 340 ? 99.493 -20.962 15.820 1.00 11.10 ? 342 THR A OG1 1 ATOM 2568 C CG2 . THR A 1 340 ? 99.779 -19.462 17.686 1.00 11.07 ? 342 THR A CG2 1 ATOM 2569 N N . SER A 1 341 ? 102.301 -19.486 14.061 1.00 13.33 ? 343 SER A N 1 ATOM 2570 C CA . SER A 1 341 ? 103.005 -19.911 12.854 1.00 14.51 ? 343 SER A CA 1 ATOM 2571 C C . SER A 1 341 ? 102.514 -21.271 12.360 1.00 12.93 ? 343 SER A C 1 ATOM 2572 O O . SER A 1 341 ? 102.337 -21.470 11.161 1.00 13.38 ? 343 SER A O 1 ATOM 2573 C CB . SER A 1 341 ? 104.519 -19.930 13.084 1.00 15.68 ? 343 SER A CB 1 ATOM 2574 O OG . SER A 1 341 ? 104.840 -20.655 14.256 1.00 19.65 ? 343 SER A OG 1 ATOM 2575 N N . ALA A 1 342 ? 102.250 -22.186 13.288 1.00 12.54 ? 344 ALA A N 1 ATOM 2576 C CA . ALA A 1 342 ? 101.755 -23.516 12.929 1.00 12.56 ? 344 ALA A CA 1 ATOM 2577 C C . ALA A 1 342 ? 100.370 -23.448 12.289 1.00 12.42 ? 344 ALA A C 1 ATOM 2578 O O . ALA A 1 342 ? 100.054 -24.216 11.378 1.00 12.46 ? 344 ALA A O 1 ATOM 2579 C CB . ALA A 1 342 ? 101.727 -24.424 14.150 1.00 12.66 ? 344 ALA A CB 1 ATOM 2580 N N . GLU A 1 343 ? 99.538 -22.537 12.779 1.00 11.79 ? 345 GLU A N 1 ATOM 2581 C CA . GLU A 1 343 ? 98.199 -22.371 12.226 1.00 12.88 ? 345 GLU A CA 1 ATOM 2582 C C . GLU A 1 343 ? 98.260 -21.750 10.836 1.00 13.14 ? 345 GLU A C 1 ATOM 2583 O O . GLU A 1 343 ? 97.581 -22.199 9.913 1.00 12.32 ? 345 GLU A O 1 ATOM 2584 C CB . GLU A 1 343 ? 97.348 -21.499 13.144 1.00 12.01 ? 345 GLU A CB 1 ATOM 2585 C CG . GLU A 1 343 ? 96.954 -22.172 14.447 1.00 12.06 ? 345 GLU A CG 1 ATOM 2586 C CD . GLU A 1 343 ? 96.294 -21.204 15.402 1.00 12.18 ? 345 GLU A CD 1 ATOM 2587 O OE1 . GLU A 1 343 ? 97.001 -20.305 15.906 1.00 11.24 ? 345 GLU A OE1 1 ATOM 2588 O OE2 . GLU A 1 343 ? 95.064 -21.316 15.608 1.00 12.20 ? 345 GLU A OE2 1 ATOM 2589 N N . SER A 1 344 ? 99.084 -20.720 10.692 1.00 13.72 ? 346 SER A N 1 ATOM 2590 C CA . SER A 1 344 ? 99.233 -20.052 9.411 1.00 16.09 ? 346 SER A CA 1 ATOM 2591 C C . SER A 1 344 ? 99.746 -21.028 8.359 1.00 16.72 ? 346 SER A C 1 ATOM 2592 O O . SER A 1 344 ? 99.318 -20.994 7.207 1.00 16.37 ? 346 SER A O 1 ATOM 2593 C CB . SER A 1 344 ? 100.180 -18.857 9.532 1.00 18.41 ? 346 SER A CB 1 ATOM 2594 O OG . SER A 1 344 ? 100.259 -18.153 8.304 1.00 22.77 ? 346 SER A OG 1 ATOM 2595 N N . ALA A 1 345 ? 100.646 -21.914 8.775 1.00 15.77 ? 347 ALA A N 1 ATOM 2596 C CA . ALA A 1 345 ? 101.273 -22.869 7.871 1.00 15.63 ? 347 ALA A CA 1 ATOM 2597 C C . ALA A 1 345 ? 100.306 -23.967 7.436 1.00 15.11 ? 347 ALA A C 1 ATOM 2598 O O . ALA A 1 345 ? 100.284 -24.366 6.272 1.00 16.21 ? 347 ALA A O 1 ATOM 2599 C CB . ALA A 1 345 ? 102.503 -23.477 8.530 1.00 15.86 ? 347 ALA A CB 1 ATOM 2600 N N . SER A 1 346 ? 99.503 -24.450 8.377 1.00 14.21 ? 348 SER A N 1 ATOM 2601 C CA . SER A 1 346 ? 98.589 -25.558 8.120 1.00 13.48 ? 348 SER A CA 1 ATOM 2602 C C . SER A 1 346 ? 97.266 -25.084 7.521 1.00 12.46 ? 348 SER A C 1 ATOM 2603 O O . SER A 1 346 ? 96.470 -25.893 7.045 1.00 12.23 ? 348 SER A O 1 ATOM 2604 C CB . SER A 1 346 ? 98.308 -26.312 9.419 1.00 13.68 ? 348 SER A CB 1 ATOM 2605 O OG . SER A 1 346 ? 97.518 -25.520 10.286 1.00 13.98 ? 348 SER A OG 1 ATOM 2606 N N . ASN A 1 347 ? 97.021 -23.778 7.583 1.00 12.17 ? 349 ASN A N 1 ATOM 2607 C CA . ASN A 1 347 ? 95.731 -23.205 7.192 1.00 12.51 ? 349 ASN A CA 1 ATOM 2608 C C . ASN A 1 347 ? 94.588 -23.604 8.112 1.00 12.57 ? 349 ASN A C 1 ATOM 2609 O O . ASN A 1 347 ? 93.418 -23.481 7.742 1.00 12.61 ? 349 ASN A O 1 ATOM 2610 C CB . ASN A 1 347 ? 95.368 -23.598 5.762 1.00 12.56 ? 349 ASN A CB 1 ATOM 2611 C CG . ASN A 1 347 ? 96.408 -23.163 4.757 1.00 13.92 ? 349 ASN A CG 1 ATOM 2612 O OD1 . ASN A 1 347 ? 96.917 -22.044 4.813 1.00 13.06 ? 349 ASN A OD1 1 ATOM 2613 N ND2 . ASN A 1 347 ? 96.739 -24.055 3.835 1.00 15.71 ? 349 ASN A ND2 1 ATOM 2614 N N . THR A 1 348 ? 94.926 -24.061 9.313 1.00 12.15 ? 350 THR A N 1 ATOM 2615 C CA . THR A 1 348 ? 93.950 -24.695 10.194 1.00 13.10 ? 350 THR A CA 1 ATOM 2616 C C . THR A 1 348 ? 94.000 -24.082 11.589 1.00 12.50 ? 350 THR A C 1 ATOM 2617 O O . THR A 1 348 ? 95.033 -24.122 12.259 1.00 13.36 ? 350 THR A O 1 ATOM 2618 C CB . THR A 1 348 ? 94.208 -26.210 10.311 1.00 14.20 ? 350 THR A CB 1 ATOM 2619 O OG1 . THR A 1 348 ? 94.082 -26.818 9.020 1.00 14.68 ? 350 THR A OG1 1 ATOM 2620 C CG2 . THR A 1 348 ? 93.217 -26.854 11.275 1.00 13.89 ? 350 THR A CG2 1 ATOM 2621 N N . THR A 1 349 ? 92.878 -23.510 12.013 1.00 11.34 ? 351 THR A N 1 ATOM 2622 C CA . THR A 1 349 ? 92.745 -22.964 13.360 1.00 10.88 ? 351 THR A CA 1 ATOM 2623 C C . THR A 1 349 ? 92.787 -24.058 14.422 1.00 10.85 ? 351 THR A C 1 ATOM 2624 O O . THR A 1 349 ? 92.077 -25.061 14.319 1.00 10.46 ? 351 THR A O 1 ATOM 2625 C CB . THR A 1 349 ? 91.420 -22.193 13.510 1.00 10.49 ? 351 THR A CB 1 ATOM 2626 O OG1 . THR A 1 349 ? 91.385 -21.116 12.569 1.00 9.94 ? 351 THR A OG1 1 ATOM 2627 C CG2 . THR A 1 349 ? 91.273 -21.640 14.928 1.00 10.36 ? 351 THR A CG2 1 ATOM 2628 N N . THR A 1 350 ? 93.601 -23.847 15.453 1.00 10.75 ? 352 THR A N 1 ATOM 2629 C CA . THR A 1 350 ? 93.566 -24.693 16.643 1.00 11.05 ? 352 THR A CA 1 ATOM 2630 C C . THR A 1 350 ? 93.316 -23.879 17.906 1.00 11.06 ? 352 THR A C 1 ATOM 2631 O O . THR A 1 350 ? 92.844 -24.409 18.907 1.00 11.24 ? 352 THR A O 1 ATOM 2632 C CB . THR A 1 350 ? 94.873 -25.492 16.827 1.00 11.35 ? 352 THR A CB 1 ATOM 2633 O OG1 . THR A 1 350 ? 95.962 -24.592 17.067 1.00 11.52 ? 352 THR A OG1 1 ATOM 2634 C CG2 . THR A 1 350 ? 95.172 -26.339 15.598 1.00 11.43 ? 352 THR A CG2 1 ATOM 2635 N N . GLN A 1 351 ? 93.653 -22.594 17.862 1.00 11.22 ? 353 GLN A N 1 ATOM 2636 C CA . GLN A 1 351 ? 93.473 -21.724 19.016 1.00 11.42 ? 353 GLN A CA 1 ATOM 2637 C C . GLN A 1 351 ? 92.312 -20.765 18.771 1.00 11.56 ? 353 GLN A C 1 ATOM 2638 O O . GLN A 1 351 ? 92.297 -20.046 17.770 1.00 11.57 ? 353 GLN A O 1 ATOM 2639 C CB . GLN A 1 351 ? 94.758 -20.942 19.292 1.00 11.19 ? 353 GLN A CB 1 ATOM 2640 C CG . GLN A 1 351 ? 96.028 -21.777 19.163 1.00 11.96 ? 353 GLN A CG 1 ATOM 2641 C CD . GLN A 1 351 ? 96.047 -22.957 20.114 1.00 12.26 ? 353 GLN A CD 1 ATOM 2642 O OE1 . GLN A 1 351 ? 96.157 -24.110 19.691 1.00 11.64 ? 353 GLN A OE1 1 ATOM 2643 N NE2 . GLN A 1 351 ? 95.899 -22.678 21.405 1.00 11.50 ? 353 GLN A NE2 1 ATOM 2644 N N . GLU A 1 352 ? 91.321 -20.778 19.657 1.00 12.00 ? 354 GLU A N 1 ATOM 2645 C CA . GLU A 1 352 ? 90.132 -19.967 19.423 1.00 11.98 ? 354 GLU A CA 1 ATOM 2646 C C . GLU A 1 352 ? 90.448 -18.485 19.541 1.00 11.38 ? 354 GLU A C 1 ATOM 2647 O O . GLU A 1 352 ? 90.997 -18.029 20.549 1.00 10.54 ? 354 GLU A O 1 ATOM 2648 C CB . GLU A 1 352 ? 88.976 -20.338 20.355 1.00 13.82 ? 354 GLU A CB 1 ATOM 2649 C CG . GLU A 1 352 ? 87.691 -19.600 19.995 1.00 15.47 ? 354 GLU A CG 1 ATOM 2650 C CD . GLU A 1 352 ? 86.578 -19.800 21.003 1.00 17.11 ? 354 GLU A CD 1 ATOM 2651 O OE1 . GLU A 1 352 ? 86.710 -20.684 21.873 1.00 18.47 ? 354 GLU A OE1 1 ATOM 2652 O OE2 . GLU A 1 352 ? 85.570 -19.065 20.923 1.00 16.65 ? 354 GLU A OE2 1 ATOM 2653 N N . ARG A 1 353 ? 90.119 -17.749 18.486 1.00 10.55 ? 355 ARG A N 1 ATOM 2654 C CA . ARG A 1 353 ? 90.233 -16.297 18.476 1.00 9.87 ? 355 ARG A CA 1 ATOM 2655 C C . ARG A 1 353 ? 89.016 -15.737 17.753 1.00 9.62 ? 355 ARG A C 1 ATOM 2656 O O . ARG A 1 353 ? 88.315 -16.461 17.045 1.00 9.55 ? 355 ARG A O 1 ATOM 2657 C CB . ARG A 1 353 ? 91.511 -15.870 17.748 1.00 10.03 ? 355 ARG A CB 1 ATOM 2658 C CG . ARG A 1 353 ? 91.624 -16.408 16.329 1.00 10.12 ? 355 ARG A CG 1 ATOM 2659 C CD . ARG A 1 353 ? 92.946 -16.014 15.683 1.00 10.57 ? 355 ARG A CD 1 ATOM 2660 N NE . ARG A 1 353 ? 94.086 -16.556 16.419 1.00 10.28 ? 355 ARG A NE 1 ATOM 2661 C CZ . ARG A 1 353 ? 94.563 -17.785 16.255 1.00 10.42 ? 355 ARG A CZ 1 ATOM 2662 N NH1 . ARG A 1 353 ? 94.023 -18.593 15.349 1.00 9.40 ? 355 ARG A NH1 1 ATOM 2663 N NH2 . ARG A 1 353 ? 95.586 -18.202 16.991 1.00 9.79 ? 355 ARG A NH2 1 ATOM 2664 N N . GLY A 1 354 ? 88.761 -14.449 17.920 1.00 8.52 ? 356 GLY A N 1 ATOM 2665 C CA . GLY A 1 354 ? 87.706 -13.815 17.149 1.00 8.63 ? 356 GLY A CA 1 ATOM 2666 C C . GLY A 1 354 ? 87.341 -12.442 17.659 1.00 8.78 ? 356 GLY A C 1 ATOM 2667 O O . GLY A 1 354 ? 88.213 -11.653 18.029 1.00 8.65 ? 356 GLY A O 1 ATOM 2668 N N . LEU A 1 355 ? 86.042 -12.166 17.669 1.00 8.23 ? 357 LEU A N 1 ATOM 2669 C CA . LEU A 1 355 ? 85.524 -10.862 18.064 1.00 8.11 ? 357 LEU A CA 1 ATOM 2670 C C . LEU A 1 355 ? 84.537 -11.027 19.210 1.00 7.98 ? 357 LEU A C 1 ATOM 2671 O O . LEU A 1 355 ? 83.569 -11.788 19.107 1.00 7.80 ? 357 LEU A O 1 ATOM 2672 C CB . LEU A 1 355 ? 84.827 -10.191 16.876 1.00 8.00 ? 357 LEU A CB 1 ATOM 2673 C CG . LEU A 1 355 ? 84.292 -8.780 17.122 1.00 8.58 ? 357 LEU A CG 1 ATOM 2674 C CD1 . LEU A 1 355 ? 85.453 -7.810 17.297 1.00 9.05 ? 357 LEU A CD1 1 ATOM 2675 C CD2 . LEU A 1 355 ? 83.395 -8.335 15.978 1.00 8.68 ? 357 LEU A CD2 1 ATOM 2676 N N . ALA A 1 356 ? 84.806 -10.351 20.320 1.00 7.66 ? 358 ALA A N 1 ATOM 2677 C CA . ALA A 1 356 ? 83.793 -10.174 21.354 1.00 8.01 ? 358 ALA A CA 1 ATOM 2678 C C . ALA A 1 356 ? 82.833 -9.075 20.917 1.00 8.32 ? 358 ALA A C 1 ATOM 2679 O O . ALA A 1 356 ? 83.084 -7.887 21.141 1.00 8.31 ? 358 ALA A O 1 ATOM 2680 C CB . ALA A 1 356 ? 84.444 -9.829 22.688 1.00 7.87 ? 358 ALA A CB 1 ATOM 2681 N N . PHE A 1 357 ? 81.782 -9.475 20.207 1.00 8.87 ? 359 PHE A N 1 ATOM 2682 C CA . PHE A 1 357 ? 80.912 -8.527 19.527 1.00 9.01 ? 359 PHE A CA 1 ATOM 2683 C C . PHE A 1 357 ? 79.949 -7.900 20.524 1.00 9.11 ? 359 PHE A C 1 ATOM 2684 O O . PHE A 1 357 ? 79.321 -8.604 21.313 1.00 9.46 ? 359 PHE A O 1 ATOM 2685 C CB . PHE A 1 357 ? 80.139 -9.225 18.407 1.00 8.95 ? 359 PHE A CB 1 ATOM 2686 C CG . PHE A 1 357 ? 79.174 -8.330 17.688 1.00 9.26 ? 359 PHE A CG 1 ATOM 2687 C CD1 . PHE A 1 357 ? 79.581 -7.586 16.593 1.00 9.59 ? 359 PHE A CD1 1 ATOM 2688 C CD2 . PHE A 1 357 ? 77.847 -8.253 18.091 1.00 9.73 ? 359 PHE A CD2 1 ATOM 2689 C CE1 . PHE A 1 357 ? 78.693 -6.763 15.927 1.00 9.71 ? 359 PHE A CE1 1 ATOM 2690 C CE2 . PHE A 1 357 ? 76.949 -7.447 17.416 1.00 9.94 ? 359 PHE A CE2 1 ATOM 2691 C CZ . PHE A 1 357 ? 77.374 -6.696 16.336 1.00 9.58 ? 359 PHE A CZ 1 ATOM 2692 N N . VAL A 1 358 ? 79.877 -6.572 20.520 1.00 9.04 ? 360 VAL A N 1 ATOM 2693 C CA . VAL A 1 358 ? 78.951 -5.853 21.384 1.00 9.32 ? 360 VAL A CA 1 ATOM 2694 C C . VAL A 1 358 ? 78.196 -4.821 20.549 1.00 9.55 ? 360 VAL A C 1 ATOM 2695 O O . VAL A 1 358 ? 78.807 -3.972 19.901 1.00 9.45 ? 360 VAL A O 1 ATOM 2696 C CB . VAL A 1 358 ? 79.695 -5.145 22.538 1.00 9.86 ? 360 VAL A CB 1 ATOM 2697 C CG1 . VAL A 1 358 ? 78.713 -4.426 23.453 1.00 9.79 ? 360 VAL A CG1 1 ATOM 2698 C CG2 . VAL A 1 358 ? 80.531 -6.142 23.329 1.00 9.25 ? 360 VAL A CG2 1 ATOM 2699 N N . ALA A 1 359 ? 76.873 -4.940 20.515 1.00 8.98 ? 361 ALA A N 1 ATOM 2700 C CA . ALA A 1 359 ? 76.040 -3.952 19.838 1.00 9.21 ? 361 ALA A CA 1 ATOM 2701 C C . ALA A 1 359 ? 75.044 -3.360 20.818 1.00 9.24 ? 361 ALA A C 1 ATOM 2702 O O . ALA A 1 359 ? 74.397 -4.094 21.570 1.00 9.04 ? 361 ALA A O 1 ATOM 2703 C CB . ALA A 1 359 ? 75.310 -4.583 18.660 1.00 8.97 ? 361 ALA A CB 1 ATOM 2704 N N . TYR A 1 360 ? 74.920 -2.035 20.798 1.00 8.77 ? 362 TYR A N 1 ATOM 2705 C CA . TYR A 1 360 ? 73.922 -1.344 21.599 1.00 9.19 ? 362 TYR A CA 1 ATOM 2706 C C . TYR A 1 360 ? 72.803 -0.786 20.724 1.00 9.23 ? 362 TYR A C 1 ATOM 2707 O O . TYR A 1 360 ? 73.047 -0.300 19.613 1.00 8.80 ? 362 TYR A O 1 ATOM 2708 C CB . TYR A 1 360 ? 74.563 -0.216 22.412 1.00 8.78 ? 362 TYR A CB 1 ATOM 2709 C CG . TYR A 1 360 ? 75.505 -0.691 23.500 1.00 9.00 ? 362 TYR A CG 1 ATOM 2710 C CD1 . TYR A 1 360 ? 75.020 -1.141 24.723 1.00 9.12 ? 362 TYR A CD1 1 ATOM 2711 C CD2 . TYR A 1 360 ? 76.882 -0.689 23.301 1.00 8.90 ? 362 TYR A CD2 1 ATOM 2712 C CE1 . TYR A 1 360 ? 75.883 -1.558 25.723 1.00 9.44 ? 362 TYR A CE1 1 ATOM 2713 C CE2 . TYR A 1 360 ? 77.751 -1.101 24.295 1.00 9.02 ? 362 TYR A CE2 1 ATOM 2714 C CZ . TYR A 1 360 ? 77.248 -1.527 25.506 1.00 9.56 ? 362 TYR A CZ 1 ATOM 2715 O OH . TYR A 1 360 ? 78.118 -1.941 26.489 1.00 10.59 ? 362 TYR A OH 1 ATOM 2716 N N . GLN A 1 361 ? 71.577 -0.886 21.230 1.00 9.26 ? 363 GLN A N 1 ATOM 2717 C CA . GLN A 1 361 ? 70.387 -0.375 20.553 1.00 9.51 ? 363 GLN A CA 1 ATOM 2718 C C . GLN A 1 361 ? 69.242 -0.289 21.559 1.00 9.25 ? 363 GLN A C 1 ATOM 2719 O O . GLN A 1 361 ? 69.264 -0.961 22.592 1.00 9.20 ? 363 GLN A O 1 ATOM 2720 C CB . GLN A 1 361 ? 69.979 -1.302 19.407 1.00 9.48 ? 363 GLN A CB 1 ATOM 2721 C CG . GLN A 1 361 ? 69.698 -2.730 19.851 1.00 9.64 ? 363 GLN A CG 1 ATOM 2722 C CD . GLN A 1 361 ? 70.915 -3.627 19.743 1.00 9.48 ? 363 GLN A CD 1 ATOM 2723 O OE1 . GLN A 1 361 ? 71.293 -4.040 18.650 1.00 10.02 ? 363 GLN A OE1 1 ATOM 2724 N NE2 . GLN A 1 361 ? 71.526 -3.947 20.881 1.00 9.20 ? 363 GLN A NE2 1 ATOM 2725 N N . ALA A 1 362 ? 68.241 0.532 21.249 1.00 9.04 ? 364 ALA A N 1 ATOM 2726 C CA . ALA A 1 362 ? 67.062 0.656 22.100 1.00 9.32 ? 364 ALA A CA 1 ATOM 2727 C C . ALA A 1 362 ? 66.055 -0.455 21.835 1.00 9.61 ? 364 ALA A C 1 ATOM 2728 O O . ALA A 1 362 ? 65.284 -0.828 22.722 1.00 9.57 ? 364 ALA A O 1 ATOM 2729 C CB . ALA A 1 362 ? 66.410 2.017 21.916 1.00 9.34 ? 364 ALA A CB 1 ATOM 2730 N N . GLN A 1 363 ? 66.036 -0.953 20.600 1.00 9.77 ? 365 GLN A N 1 ATOM 2731 C CA . GLN A 1 363 ? 65.190 -2.093 20.248 1.00 9.92 ? 365 GLN A CA 1 ATOM 2732 C C . GLN A 1 363 ? 66.003 -3.194 19.572 1.00 9.67 ? 365 GLN A C 1 ATOM 2733 O O . GLN A 1 363 ? 66.485 -3.022 18.452 1.00 10.50 ? 365 GLN A O 1 ATOM 2734 C CB . GLN A 1 363 ? 64.052 -1.655 19.326 1.00 10.60 ? 365 GLN A CB 1 ATOM 2735 C CG . GLN A 1 363 ? 63.097 -0.646 19.945 1.00 10.98 ? 365 GLN A CG 1 ATOM 2736 C CD . GLN A 1 363 ? 62.003 -0.215 18.985 1.00 12.26 ? 365 GLN A CD 1 ATOM 2737 O OE1 . GLN A 1 363 ? 61.972 0.933 18.533 1.00 12.77 ? 365 GLN A OE1 1 ATOM 2738 N NE2 . GLN A 1 363 ? 61.106 -1.141 18.656 1.00 11.33 ? 365 GLN A NE2 1 ATOM 2739 N N . LEU A 1 364 ? 66.128 -4.334 20.240 1.00 9.28 ? 366 LEU A N 1 ATOM 2740 C CA . LEU A 1 364 ? 66.819 -5.480 19.655 1.00 9.86 ? 366 LEU A CA 1 ATOM 2741 C C . LEU A 1 364 ? 66.202 -5.915 18.328 1.00 10.55 ? 366 LEU A C 1 ATOM 2742 O O . LEU A 1 364 ? 66.911 -6.332 17.413 1.00 10.62 ? 366 LEU A O 1 ATOM 2743 C CB . LEU A 1 364 ? 66.864 -6.647 20.640 1.00 9.61 ? 366 LEU A CB 1 ATOM 2744 C CG . LEU A 1 364 ? 67.816 -6.446 21.823 1.00 10.19 ? 366 LEU A CG 1 ATOM 2745 C CD1 . LEU A 1 364 ? 67.469 -7.382 22.976 1.00 10.33 ? 366 LEU A CD1 1 ATOM 2746 C CD2 . LEU A 1 364 ? 69.260 -6.639 21.389 1.00 9.49 ? 366 LEU A CD2 1 ATOM 2747 N N . SER A 1 365 ? 64.890 -5.754 18.196 1.00 10.66 ? 367 SER A N 1 ATOM 2748 C CA . SER A 1 365 ? 64.200 -6.213 16.993 1.00 11.25 ? 367 SER A CA 1 ATOM 2749 C C . SER A 1 365 ? 64.532 -5.353 15.778 1.00 11.81 ? 367 SER A C 1 ATOM 2750 O O . SER A 1 365 ? 64.324 -5.775 14.638 1.00 11.37 ? 367 SER A O 1 ATOM 2751 C CB . SER A 1 365 ? 62.687 -6.241 17.212 1.00 11.07 ? 367 SER A CB 1 ATOM 2752 O OG . SER A 1 365 ? 62.171 -4.927 17.277 1.00 11.31 ? 367 SER A OG 1 ATOM 2753 N N . GLN A 1 366 ? 65.024 -4.140 16.030 1.00 12.04 ? 368 GLN A N 1 ATOM 2754 C CA . GLN A 1 366 ? 65.355 -3.196 14.963 1.00 13.39 ? 368 GLN A CA 1 ATOM 2755 C C . GLN A 1 366 ? 66.858 -3.144 14.699 1.00 11.99 ? 368 GLN A C 1 ATOM 2756 O O . GLN A 1 366 ? 67.296 -2.680 13.647 1.00 11.14 ? 368 GLN A O 1 ATOM 2757 C CB . GLN A 1 366 ? 64.850 -1.795 15.310 1.00 14.75 ? 368 GLN A CB 1 ATOM 2758 C CG . GLN A 1 366 ? 63.350 -1.718 15.533 1.00 16.60 ? 368 GLN A CG 1 ATOM 2759 C CD . GLN A 1 366 ? 62.558 -2.057 14.286 1.00 18.97 ? 368 GLN A CD 1 ATOM 2760 O OE1 . GLN A 1 366 ? 62.667 -1.378 13.265 1.00 21.30 ? 368 GLN A OE1 1 ATOM 2761 N NE2 . GLN A 1 366 ? 61.747 -3.107 14.365 1.00 21.44 ? 368 GLN A NE2 1 ATOM 2762 N N . GLY A 1 367 ? 67.639 -3.618 15.664 1.00 11.00 ? 369 GLY A N 1 ATOM 2763 C CA . GLY A 1 367 ? 69.090 -3.502 15.605 1.00 10.36 ? 369 GLY A CA 1 ATOM 2764 C C . GLY A 1 367 ? 69.767 -4.799 15.216 1.00 10.44 ? 369 GLY A C 1 ATOM 2765 O O . GLY A 1 367 ? 69.567 -5.312 14.111 1.00 10.58 ? 369 GLY A O 1 ATOM 2766 N N . PHE A 1 368 ? 70.565 -5.339 16.133 1.00 9.97 ? 370 PHE A N 1 ATOM 2767 C CA . PHE A 1 368 ? 71.384 -6.506 15.838 1.00 9.79 ? 370 PHE A CA 1 ATOM 2768 C C . PHE A 1 368 ? 70.570 -7.644 15.222 1.00 10.20 ? 370 PHE A C 1 ATOM 2769 O O . PHE A 1 368 ? 70.953 -8.206 14.194 1.00 9.64 ? 370 PHE A O 1 ATOM 2770 C CB . PHE A 1 368 ? 72.098 -7.001 17.097 1.00 9.93 ? 370 PHE A CB 1 ATOM 2771 C CG . PHE A 1 368 ? 72.515 -8.441 17.020 1.00 10.17 ? 370 PHE A CG 1 ATOM 2772 C CD1 . PHE A 1 368 ? 73.604 -8.820 16.254 1.00 10.51 ? 370 PHE A CD1 1 ATOM 2773 C CD2 . PHE A 1 368 ? 71.767 -9.427 17.645 1.00 10.62 ? 370 PHE A CD2 1 ATOM 2774 C CE1 . PHE A 1 368 ? 73.967 -10.149 16.145 1.00 10.57 ? 370 PHE A CE1 1 ATOM 2775 C CE2 . PHE A 1 368 ? 72.132 -10.757 17.552 1.00 10.91 ? 370 PHE A CE2 1 ATOM 2776 C CZ . PHE A 1 368 ? 73.228 -11.121 16.791 1.00 10.87 ? 370 PHE A CZ 1 ATOM 2777 N N . HIS A 1 369 ? 69.458 -7.988 15.862 1.00 10.00 ? 371 HIS A N 1 ATOM 2778 C CA . HIS A 1 369 ? 68.637 -9.117 15.428 1.00 10.55 ? 371 HIS A CA 1 ATOM 2779 C C . HIS A 1 369 ? 68.130 -8.893 14.006 1.00 10.78 ? 371 HIS A C 1 ATOM 2780 O O . HIS A 1 369 ? 68.182 -9.794 13.164 1.00 10.89 ? 371 HIS A O 1 ATOM 2781 C CB . HIS A 1 369 ? 67.471 -9.323 16.406 1.00 11.18 ? 371 HIS A CB 1 ATOM 2782 C CG . HIS A 1 369 ? 66.409 -10.255 15.906 1.00 11.84 ? 371 HIS A CG 1 ATOM 2783 N ND1 . HIS A 1 369 ? 66.213 -11.512 16.437 1.00 11.90 ? 371 HIS A ND1 1 ATOM 2784 C CD2 . HIS A 1 369 ? 65.439 -10.086 14.976 1.00 12.77 ? 371 HIS A CD2 1 ATOM 2785 C CE1 . HIS A 1 369 ? 65.194 -12.092 15.828 1.00 12.42 ? 371 HIS A CE1 1 ATOM 2786 N NE2 . HIS A 1 369 ? 64.705 -11.247 14.938 1.00 13.97 ? 371 HIS A NE2 1 ATOM 2787 N N . PHE A 1 370 ? 67.708 -7.663 13.725 1.00 10.63 ? 372 PHE A N 1 ATOM 2788 C CA . PHE A 1 370 ? 67.216 -7.295 12.400 1.00 11.17 ? 372 PHE A CA 1 ATOM 2789 C C . PHE A 1 370 ? 68.322 -7.381 11.352 1.00 10.66 ? 372 PHE A C 1 ATOM 2790 O O . PHE A 1 370 ? 68.141 -7.984 10.292 1.00 10.68 ? 372 PHE A O 1 ATOM 2791 C CB . PHE A 1 370 ? 66.633 -5.878 12.430 1.00 11.69 ? 372 PHE A CB 1 ATOM 2792 C CG . PHE A 1 370 ? 65.847 -5.516 11.202 1.00 13.04 ? 372 PHE A CG 1 ATOM 2793 C CD1 . PHE A 1 370 ? 64.545 -5.966 11.040 1.00 13.34 ? 372 PHE A CD1 1 ATOM 2794 C CD2 . PHE A 1 370 ? 66.408 -4.730 10.209 1.00 12.87 ? 372 PHE A CD2 1 ATOM 2795 C CE1 . PHE A 1 370 ? 63.820 -5.641 9.907 1.00 13.85 ? 372 PHE A CE1 1 ATOM 2796 C CE2 . PHE A 1 370 ? 65.683 -4.390 9.082 1.00 12.93 ? 372 PHE A CE2 1 ATOM 2797 C CZ . PHE A 1 370 ? 64.384 -4.840 8.933 1.00 13.44 ? 372 PHE A CZ 1 ATOM 2798 N N . LEU A 1 371 ? 69.462 -6.760 11.645 1.00 10.25 ? 373 LEU A N 1 ATOM 2799 C CA . LEU A 1 371 ? 70.602 -6.776 10.734 1.00 10.52 ? 373 LEU A CA 1 ATOM 2800 C C . LEU A 1 371 ? 71.027 -8.202 10.389 1.00 10.09 ? 373 LEU A C 1 ATOM 2801 O O . LEU A 1 371 ? 71.327 -8.510 9.233 1.00 10.34 ? 373 LEU A O 1 ATOM 2802 C CB . LEU A 1 371 ? 71.784 -5.999 11.328 1.00 10.54 ? 373 LEU A CB 1 ATOM 2803 C CG . LEU A 1 371 ? 71.912 -4.517 10.947 1.00 10.75 ? 373 LEU A CG 1 ATOM 2804 C CD1 . LEU A 1 371 ? 70.576 -3.804 11.085 1.00 10.79 ? 373 LEU A CD1 1 ATOM 2805 C CD2 . LEU A 1 371 ? 72.971 -3.825 11.800 1.00 10.44 ? 373 LEU A CD2 1 ATOM 2806 N N . GLN A 1 372 ? 71.069 -9.068 11.395 1.00 10.19 ? 374 GLN A N 1 ATOM 2807 C CA . GLN A 1 372 ? 71.499 -10.444 11.180 1.00 10.29 ? 374 GLN A CA 1 ATOM 2808 C C . GLN A 1 372 ? 70.481 -11.231 10.354 1.00 10.85 ? 374 GLN A C 1 ATOM 2809 O O . GLN A 1 372 ? 70.837 -11.874 9.367 1.00 10.90 ? 374 GLN A O 1 ATOM 2810 C CB . GLN A 1 372 ? 71.764 -11.146 12.512 1.00 10.23 ? 374 GLN A CB 1 ATOM 2811 C CG . GLN A 1 372 ? 72.211 -12.593 12.369 1.00 10.29 ? 374 GLN A CG 1 ATOM 2812 C CD . GLN A 1 372 ? 73.648 -12.717 11.895 1.00 10.31 ? 374 GLN A CD 1 ATOM 2813 O OE1 . GLN A 1 372 ? 74.576 -12.234 12.548 1.00 10.30 ? 374 GLN A OE1 1 ATOM 2814 N NE2 . GLN A 1 372 ? 73.836 -13.343 10.742 1.00 10.61 ? 374 GLN A NE2 1 ATOM 2815 N N . GLN A 1 373 ? 69.218 -11.184 10.763 1.00 10.68 ? 375 GLN A N 1 ATOM 2816 C CA . GLN A 1 373 ? 68.202 -12.055 10.173 1.00 11.42 ? 375 GLN A CA 1 ATOM 2817 C C . GLN A 1 373 ? 67.651 -11.513 8.857 1.00 11.36 ? 375 GLN A C 1 ATOM 2818 O O . GLN A 1 373 ? 67.581 -12.231 7.858 1.00 11.68 ? 375 GLN A O 1 ATOM 2819 C CB . GLN A 1 373 ? 67.056 -12.314 11.154 1.00 12.29 ? 375 GLN A CB 1 ATOM 2820 C CG . GLN A 1 373 ? 65.899 -13.089 10.535 1.00 13.79 ? 375 GLN A CG 1 ATOM 2821 C CD . GLN A 1 373 ? 64.737 -13.280 11.487 1.00 16.39 ? 375 GLN A CD 1 ATOM 2822 O OE1 . GLN A 1 373 ? 64.141 -14.358 11.552 1.00 18.96 ? 375 GLN A OE1 1 ATOM 2823 N NE2 . GLN A 1 373 ? 64.398 -12.231 12.220 1.00 15.91 ? 375 GLN A NE2 1 ATOM 2824 N N . THR A 1 374 ? 67.246 -10.250 8.858 1.00 11.12 ? 376 THR A N 1 ATOM 2825 C CA . THR A 1 374 ? 66.468 -9.722 7.746 1.00 11.26 ? 376 THR A CA 1 ATOM 2826 C C . THR A 1 374 ? 67.358 -9.233 6.610 1.00 11.03 ? 376 THR A C 1 ATOM 2827 O O . THR A 1 374 ? 66.949 -9.228 5.452 1.00 11.22 ? 376 THR A O 1 ATOM 2828 C CB . THR A 1 374 ? 65.500 -8.612 8.200 1.00 11.71 ? 376 THR A CB 1 ATOM 2829 O OG1 . THR A 1 374 ? 64.625 -9.133 9.208 1.00 12.88 ? 376 THR A OG1 1 ATOM 2830 C CG2 . THR A 1 374 ? 64.661 -8.126 7.030 1.00 11.93 ? 376 THR A CG2 1 ATOM 2831 N N . TRP A 1 375 ? 68.596 -8.871 6.937 1.00 10.75 ? 377 TRP A N 1 ATOM 2832 C CA . TRP A 1 375 ? 69.505 -8.317 5.938 1.00 10.34 ? 377 TRP A CA 1 ATOM 2833 C C . TRP A 1 375 ? 70.632 -9.280 5.576 1.00 9.82 ? 377 TRP A C 1 ATOM 2834 O O . TRP A 1 375 ? 70.701 -9.764 4.446 1.00 9.65 ? 377 TRP A O 1 ATOM 2835 C CB . TRP A 1 375 ? 70.072 -6.979 6.409 1.00 10.45 ? 377 TRP A CB 1 ATOM 2836 C CG . TRP A 1 375 ? 69.059 -5.876 6.404 1.00 10.77 ? 377 TRP A CG 1 ATOM 2837 C CD1 . TRP A 1 375 ? 67.779 -5.938 5.931 1.00 11.33 ? 377 TRP A CD1 1 ATOM 2838 C CD2 . TRP A 1 375 ? 69.256 -4.529 6.853 1.00 10.81 ? 377 TRP A CD2 1 ATOM 2839 N NE1 . TRP A 1 375 ? 67.161 -4.716 6.078 1.00 11.07 ? 377 TRP A NE1 1 ATOM 2840 C CE2 . TRP A 1 375 ? 68.046 -3.836 6.644 1.00 10.93 ? 377 TRP A CE2 1 ATOM 2841 C CE3 . TRP A 1 375 ? 70.331 -3.849 7.432 1.00 10.36 ? 377 TRP A CE3 1 ATOM 2842 C CZ2 . TRP A 1 375 ? 67.884 -2.494 6.990 1.00 11.18 ? 377 TRP A CZ2 1 ATOM 2843 C CZ3 . TRP A 1 375 ? 70.171 -2.515 7.767 1.00 10.79 ? 377 TRP A CZ3 1 ATOM 2844 C CH2 . TRP A 1 375 ? 68.961 -1.849 7.533 1.00 10.73 ? 377 TRP A CH2 1 ATOM 2845 N N . ALA A 1 376 ? 71.496 -9.574 6.544 1.00 9.38 ? 378 ALA A N 1 ATOM 2846 C CA . ALA A 1 376 ? 72.668 -10.416 6.302 1.00 9.34 ? 378 ALA A CA 1 ATOM 2847 C C . ALA A 1 376 ? 72.303 -11.824 5.827 1.00 9.39 ? 378 ALA A C 1 ATOM 2848 O O . ALA A 1 376 ? 72.998 -12.402 4.992 1.00 9.13 ? 378 ALA A O 1 ATOM 2849 C CB . ALA A 1 376 ? 73.539 -10.485 7.552 1.00 8.72 ? 378 ALA A CB 1 ATOM 2850 N N . ASP A 1 377 ? 71.228 -12.379 6.379 1.00 10.08 ? 379 ASP A N 1 ATOM 2851 C CA . ASP A 1 377 ? 70.868 -13.774 6.133 1.00 11.18 ? 379 ASP A CA 1 ATOM 2852 C C . ASP A 1 377 ? 69.862 -13.903 4.995 1.00 11.14 ? 379 ASP A C 1 ATOM 2853 O O . ASP A 1 377 ? 69.373 -14.998 4.702 1.00 11.36 ? 379 ASP A O 1 ATOM 2854 C CB . ASP A 1 377 ? 70.286 -14.405 7.399 1.00 11.86 ? 379 ASP A CB 1 ATOM 2855 C CG . ASP A 1 377 ? 71.340 -14.680 8.457 1.00 12.24 ? 379 ASP A CG 1 ATOM 2856 O OD1 . ASP A 1 377 ? 72.544 -14.502 8.169 1.00 13.34 ? 379 ASP A OD1 1 ATOM 2857 O OD2 . ASP A 1 377 ? 70.962 -15.073 9.582 1.00 13.10 ? 379 ASP A OD2 1 ATOM 2858 N N . ASN A 1 378 ? 69.543 -12.776 4.369 1.00 10.76 ? 380 ASN A N 1 ATOM 2859 C CA . ASN A 1 378 ? 68.496 -12.721 3.359 1.00 10.82 ? 380 ASN A CA 1 ATOM 2860 C C . ASN A 1 378 ? 69.096 -12.571 1.963 1.00 11.29 ? 380 ASN A C 1 ATOM 2861 O O . ASN A 1 378 ? 69.686 -11.539 1.641 1.00 11.07 ? 380 ASN A O 1 ATOM 2862 C CB . ASN A 1 378 ? 67.559 -11.550 3.672 1.00 10.73 ? 380 ASN A CB 1 ATOM 2863 C CG . ASN A 1 378 ? 66.455 -11.382 2.649 1.00 11.27 ? 380 ASN A CG 1 ATOM 2864 O OD1 . ASN A 1 378 ? 66.465 -12.003 1.586 1.00 10.79 ? 380 ASN A OD1 1 ATOM 2865 N ND2 . ASN A 1 378 ? 65.509 -10.500 2.955 1.00 12.30 ? 380 ASN A ND2 1 ATOM 2866 N N . ALA A 1 379 ? 68.966 -13.616 1.149 1.00 11.00 ? 381 ALA A N 1 ATOM 2867 C CA . ALA A 1 379 ? 69.628 -13.674 -0.152 1.00 11.82 ? 381 ALA A CA 1 ATOM 2868 C C . ALA A 1 379 ? 69.036 -12.698 -1.163 1.00 11.77 ? 381 ALA A C 1 ATOM 2869 O O . ALA A 1 379 ? 69.598 -12.496 -2.237 1.00 11.77 ? 381 ALA A O 1 ATOM 2870 C CB . ALA A 1 379 ? 69.597 -15.091 -0.707 1.00 11.60 ? 381 ALA A CB 1 ATOM 2871 N N . ASN A 1 380 ? 67.899 -12.099 -0.824 1.00 13.58 ? 382 ASN A N 1 ATOM 2872 C CA . ASN A 1 380 ? 67.320 -11.055 -1.663 1.00 14.63 ? 382 ASN A CA 1 ATOM 2873 C C . ASN A 1 380 ? 67.344 -9.684 -0.999 1.00 14.04 ? 382 ASN A C 1 ATOM 2874 O O . ASN A 1 380 ? 66.487 -8.843 -1.265 1.00 12.91 ? 382 ASN A O 1 ATOM 2875 C CB . ASN A 1 380 ? 65.891 -11.416 -2.073 1.00 17.36 ? 382 ASN A CB 1 ATOM 2876 C CG . ASN A 1 380 ? 65.848 -12.393 -3.232 1.00 20.95 ? 382 ASN A CG 1 ATOM 2877 O OD1 . ASN A 1 380 ? 65.312 -13.495 -3.110 1.00 24.51 ? 382 ASN A OD1 1 ATOM 2878 N ND2 . ASN A 1 380 ? 66.428 -11.999 -4.363 1.00 21.22 ? 382 ASN A ND2 1 ATOM 2879 N N . PHE A 1 381 ? 68.319 -9.469 -0.123 1.00 12.67 ? 383 PHE A N 1 ATOM 2880 C CA . PHE A 1 381 ? 68.591 -8.134 0.388 1.00 12.21 ? 383 PHE A CA 1 ATOM 2881 C C . PHE A 1 381 ? 70.009 -7.705 0.026 1.00 12.15 ? 383 PHE A C 1 ATOM 2882 O O . PHE A 1 381 ? 70.947 -8.487 0.171 1.00 11.50 ? 383 PHE A O 1 ATOM 2883 C CB . PHE A 1 381 ? 68.404 -8.083 1.907 1.00 12.16 ? 383 PHE A CB 1 ATOM 2884 C CG . PHE A 1 381 ? 68.486 -6.695 2.465 1.00 12.18 ? 383 PHE A CG 1 ATOM 2885 C CD1 . PHE A 1 381 ? 67.361 -5.884 2.494 1.00 12.45 ? 383 PHE A CD1 1 ATOM 2886 C CD2 . PHE A 1 381 ? 69.710 -6.150 2.813 1.00 12.09 ? 383 PHE A CD2 1 ATOM 2887 C CE1 . PHE A 1 381 ? 67.444 -4.574 2.927 1.00 12.21 ? 383 PHE A CE1 1 ATOM 2888 C CE2 . PHE A 1 381 ? 69.803 -4.837 3.240 1.00 12.66 ? 383 PHE A CE2 1 ATOM 2889 C CZ . PHE A 1 381 ? 68.669 -4.049 3.295 1.00 11.93 ? 383 PHE A CZ 1 ATOM 2890 N N . PRO A 1 382 ? 70.174 -6.467 -0.437 1.00 11.99 ? 384 PRO A N 1 ATOM 2891 C CA . PRO A 1 382 ? 69.081 -5.504 -0.572 1.00 12.05 ? 384 PRO A CA 1 ATOM 2892 C C . PRO A 1 382 ? 68.123 -5.836 -1.717 1.00 11.91 ? 384 PRO A C 1 ATOM 2893 O O . PRO A 1 382 ? 68.486 -6.574 -2.629 1.00 11.89 ? 384 PRO A O 1 ATOM 2894 C CB . PRO A 1 382 ? 69.817 -4.193 -0.886 1.00 12.11 ? 384 PRO A CB 1 ATOM 2895 C CG . PRO A 1 382 ? 71.098 -4.632 -1.520 1.00 12.08 ? 384 PRO A CG 1 ATOM 2896 C CD . PRO A 1 382 ? 71.481 -5.863 -0.752 1.00 11.82 ? 384 PRO A CD 1 ATOM 2897 N N . PRO A 1 383 ? 66.912 -5.257 -1.685 1.00 13.08 ? 385 PRO A N 1 ATOM 2898 C CA . PRO A 1 383 ? 65.886 -5.532 -2.688 1.00 13.37 ? 385 PRO A CA 1 ATOM 2899 C C . PRO A 1 383 ? 66.114 -4.757 -3.986 1.00 14.45 ? 385 PRO A C 1 ATOM 2900 O O . PRO A 1 383 ? 66.878 -3.793 -4.006 1.00 14.29 ? 385 PRO A O 1 ATOM 2901 C CB . PRO A 1 383 ? 64.603 -5.059 -2.006 1.00 14.30 ? 385 PRO A CB 1 ATOM 2902 C CG . PRO A 1 383 ? 65.049 -3.970 -1.090 1.00 13.70 ? 385 PRO A CG 1 ATOM 2903 C CD . PRO A 1 383 ? 66.432 -4.345 -0.630 1.00 13.41 ? 385 PRO A CD 1 ATOM 2904 N N . GLY A 1 384 ? 65.472 -5.198 -5.064 1.00 14.96 ? 386 GLY A N 1 ATOM 2905 C CA . GLY A 1 384 ? 65.418 -4.425 -6.302 1.00 15.04 ? 386 GLY A CA 1 ATOM 2906 C C . GLY A 1 384 ? 66.720 -4.383 -7.080 1.00 15.68 ? 386 GLY A C 1 ATOM 2907 O O . GLY A 1 384 ? 66.932 -3.484 -7.896 1.00 16.35 ? 386 GLY A O 1 ATOM 2908 N N . LYS A 1 385 ? 67.584 -5.370 -6.859 1.00 15.06 ? 387 LYS A N 1 ATOM 2909 C CA . LYS A 1 385 ? 68.851 -5.442 -7.586 1.00 14.49 ? 387 LYS A CA 1 ATOM 2910 C C . LYS A 1 385 ? 68.755 -6.351 -8.812 1.00 14.94 ? 387 LYS A C 1 ATOM 2911 O O . LYS A 1 385 ? 67.831 -7.156 -8.933 1.00 15.33 ? 387 LYS A O 1 ATOM 2912 C CB . LYS A 1 385 ? 69.983 -5.914 -6.666 1.00 14.35 ? 387 LYS A CB 1 ATOM 2913 C CG . LYS A 1 385 ? 70.242 -5.010 -5.469 1.00 13.93 ? 387 LYS A CG 1 ATOM 2914 C CD . LYS A 1 385 ? 70.497 -3.574 -5.896 1.00 14.01 ? 387 LYS A CD 1 ATOM 2915 C CE . LYS A 1 385 ? 71.129 -2.772 -4.768 1.00 13.63 ? 387 LYS A CE 1 ATOM 2916 N NZ . LYS A 1 385 ? 71.296 -1.334 -5.121 1.00 13.57 ? 387 LYS A NZ 1 ATOM 2917 N N . THR A 1 386 ? 69.709 -6.199 -9.725 1.00 14.50 ? 388 THR A N 1 ATOM 2918 C CA . THR A 1 386 ? 69.877 -7.130 -10.838 1.00 15.73 ? 388 THR A CA 1 ATOM 2919 C C . THR A 1 386 ? 71.332 -7.592 -10.884 1.00 14.90 ? 388 THR A C 1 ATOM 2920 O O . THR A 1 386 ? 72.232 -6.767 -10.995 1.00 16.22 ? 388 THR A O 1 ATOM 2921 C CB . THR A 1 386 ? 69.548 -6.447 -12.180 1.00 15.58 ? 388 THR A CB 1 ATOM 2922 O OG1 . THR A 1 386 ? 68.225 -5.897 -12.130 1.00 17.24 ? 388 THR A OG1 1 ATOM 2923 C CG2 . THR A 1 386 ? 69.642 -7.442 -13.329 1.00 16.69 ? 388 THR A CG2 1 ATOM 2924 N N . PRO A 1 387 ? 71.571 -8.896 -10.772 1.00 15.28 ? 389 PRO A N 1 ATOM 2925 C CA . PRO A 1 387 ? 70.524 -9.885 -10.540 1.00 14.81 ? 389 PRO A CA 1 ATOM 2926 C C . PRO A 1 387 ? 69.892 -9.743 -9.158 1.00 15.15 ? 389 PRO A C 1 ATOM 2927 O O . PRO A 1 387 ? 70.514 -9.200 -8.243 1.00 14.71 ? 389 PRO A O 1 ATOM 2928 C CB . PRO A 1 387 ? 71.281 -11.215 -10.627 1.00 15.18 ? 389 PRO A CB 1 ATOM 2929 C CG . PRO A 1 387 ? 72.435 -10.929 -11.529 1.00 15.70 ? 389 PRO A CG 1 ATOM 2930 C CD . PRO A 1 387 ? 72.825 -9.506 -11.251 1.00 14.80 ? 389 PRO A CD 1 ATOM 2931 N N . ALA A 1 388 ? 68.679 -10.269 -9.009 1.00 14.46 ? 390 ALA A N 1 ATOM 2932 C CA . ALA A 1 388 ? 67.904 -10.106 -7.786 1.00 14.80 ? 390 ALA A CA 1 ATOM 2933 C C . ALA A 1 388 ? 68.525 -10.833 -6.600 1.00 14.29 ? 390 ALA A C 1 ATOM 2934 O O . ALA A 1 388 ? 68.403 -10.384 -5.460 1.00 13.83 ? 390 ALA A O 1 ATOM 2935 C CB . ALA A 1 388 ? 66.471 -10.574 -8.001 1.00 15.40 ? 390 ALA A CB 1 ATOM 2936 N N . THR A 1 389 ? 69.160 -11.972 -6.869 1.00 14.26 ? 391 THR A N 1 ATOM 2937 C CA . THR A 1 389 ? 69.781 -12.769 -5.815 1.00 14.08 ? 391 THR A CA 1 ATOM 2938 C C . THR A 1 389 ? 71.137 -12.203 -5.411 1.00 13.88 ? 391 THR A C 1 ATOM 2939 O O . THR A 1 389 ? 72.149 -12.447 -6.074 1.00 13.73 ? 391 THR A O 1 ATOM 2940 C CB . THR A 1 389 ? 69.952 -14.240 -6.236 1.00 15.38 ? 391 THR A CB 1 ATOM 2941 O OG1 . THR A 1 389 ? 68.729 -14.723 -6.808 1.00 16.37 ? 391 THR A OG1 1 ATOM 2942 C CG2 . THR A 1 389 ? 70.317 -15.103 -5.030 1.00 15.17 ? 391 THR A CG2 1 ATOM 2943 N N . VAL A 1 390 ? 71.151 -11.464 -4.306 1.00 11.98 ? 392 VAL A N 1 ATOM 2944 C CA . VAL A 1 390 ? 72.376 -10.886 -3.778 1.00 11.57 ? 392 VAL A CA 1 ATOM 2945 C C . VAL A 1 390 ? 73.228 -11.965 -3.109 1.00 11.07 ? 392 VAL A C 1 ATOM 2946 O O . VAL A 1 390 ? 74.456 -11.953 -3.202 1.00 11.37 ? 392 VAL A O 1 ATOM 2947 C CB . VAL A 1 390 ? 72.060 -9.774 -2.762 1.00 11.77 ? 392 VAL A CB 1 ATOM 2948 C CG1 . VAL A 1 390 ? 73.305 -9.394 -1.973 1.00 11.62 ? 392 VAL A CG1 1 ATOM 2949 C CG2 . VAL A 1 390 ? 71.469 -8.564 -3.475 1.00 12.30 ? 392 VAL A CG2 1 ATOM 2950 N N . GLY A 1 391 ? 72.562 -12.929 -2.482 1.00 10.44 ? 393 GLY A N 1 ATOM 2951 C CA . GLY A 1 391 ? 73.246 -13.924 -1.672 1.00 10.20 ? 393 GLY A CA 1 ATOM 2952 C C . GLY A 1 391 ? 73.440 -13.405 -0.262 1.00 9.42 ? 393 GLY A C 1 ATOM 2953 O O . GLY A 1 391 ? 72.930 -12.337 0.089 1.00 9.31 ? 393 GLY A O 1 ATOM 2954 N N . LEU A 1 392 ? 74.166 -14.164 0.552 1.00 9.16 ? 394 LEU A N 1 ATOM 2955 C CA . LEU A 1 392 ? 74.306 -13.842 1.967 1.00 9.63 ? 394 LEU A CA 1 ATOM 2956 C C . LEU A 1 392 ? 75.529 -12.964 2.233 1.00 9.79 ? 394 LEU A C 1 ATOM 2957 O O . LEU A 1 392 ? 76.438 -12.890 1.409 1.00 10.72 ? 394 LEU A O 1 ATOM 2958 C CB . LEU A 1 392 ? 74.388 -15.123 2.800 1.00 9.70 ? 394 LEU A CB 1 ATOM 2959 C CG . LEU A 1 392 ? 73.242 -16.121 2.615 1.00 10.03 ? 394 LEU A CG 1 ATOM 2960 C CD1 . LEU A 1 392 ? 73.305 -17.201 3.684 1.00 10.00 ? 394 LEU A CD1 1 ATOM 2961 C CD2 . LEU A 1 392 ? 71.891 -15.423 2.636 1.00 10.00 ? 394 LEU A CD2 1 ATOM 2962 N N . ASP A 1 393 ? 75.533 -12.294 3.382 1.00 9.77 ? 395 ASP A N 1 ATOM 2963 C CA . ASP A 1 393 ? 76.730 -11.639 3.912 1.00 10.07 ? 395 ASP A CA 1 ATOM 2964 C C . ASP A 1 393 ? 77.855 -12.662 4.073 1.00 9.68 ? 395 ASP A C 1 ATOM 2965 O O . ASP A 1 393 ? 77.721 -13.617 4.837 1.00 10.52 ? 395 ASP A O 1 ATOM 2966 C CB . ASP A 1 393 ? 76.402 -10.998 5.269 1.00 10.13 ? 395 ASP A CB 1 ATOM 2967 C CG . ASP A 1 393 ? 77.515 -10.098 5.790 1.00 10.63 ? 395 ASP A CG 1 ATOM 2968 O OD1 . ASP A 1 393 ? 78.687 -10.526 5.790 1.00 10.36 ? 395 ASP A OD1 1 ATOM 2969 O OD2 . ASP A 1 393 ? 77.199 -8.990 6.277 1.00 10.59 ? 395 ASP A OD2 1 ATOM 2970 N N . PRO A 1 394 ? 78.969 -12.466 3.351 1.00 9.16 ? 396 PRO A N 1 ATOM 2971 C CA . PRO A 1 394 ? 80.056 -13.444 3.346 1.00 8.99 ? 396 PRO A CA 1 ATOM 2972 C C . PRO A 1 394 ? 80.790 -13.500 4.684 1.00 9.07 ? 396 PRO A C 1 ATOM 2973 O O . PRO A 1 394 ? 81.442 -14.499 4.985 1.00 9.56 ? 396 PRO A O 1 ATOM 2974 C CB . PRO A 1 394 ? 80.984 -12.930 2.240 1.00 9.09 ? 396 PRO A CB 1 ATOM 2975 C CG . PRO A 1 394 ? 80.723 -11.461 2.192 1.00 9.17 ? 396 PRO A CG 1 ATOM 2976 C CD . PRO A 1 394 ? 79.256 -11.314 2.477 1.00 9.03 ? 396 PRO A CD 1 ATOM 2977 N N . ILE A 1 395 ? 80.644 -12.456 5.495 1.00 8.48 ? 397 ILE A N 1 ATOM 2978 C CA . ILE A 1 395 ? 81.309 -12.399 6.796 1.00 8.79 ? 397 ILE A CA 1 ATOM 2979 C C . ILE A 1 395 ? 80.454 -13.003 7.909 1.00 8.95 ? 397 ILE A C 1 ATOM 2980 O O . ILE A 1 395 ? 80.921 -13.866 8.650 1.00 10.07 ? 397 ILE A O 1 ATOM 2981 C CB . ILE A 1 395 ? 81.731 -10.957 7.163 1.00 8.49 ? 397 ILE A CB 1 ATOM 2982 C CG1 . ILE A 1 395 ? 82.653 -10.376 6.082 1.00 7.95 ? 397 ILE A CG1 1 ATOM 2983 C CG2 . ILE A 1 395 ? 82.400 -10.911 8.530 1.00 8.46 ? 397 ILE A CG2 1 ATOM 2984 C CD1 . ILE A 1 395 ? 83.933 -11.159 5.872 1.00 8.33 ? 397 ILE A CD1 1 ATOM 2985 N N . ILE A 1 396 ? 79.201 -12.568 8.021 1.00 9.08 ? 398 ILE A N 1 ATOM 2986 C CA . ILE A 1 396 ? 78.352 -13.021 9.126 1.00 9.18 ? 398 ILE A CA 1 ATOM 2987 C C . ILE A 1 396 ? 77.110 -13.796 8.692 1.00 9.53 ? 398 ILE A C 1 ATOM 2988 O O . ILE A 1 396 ? 76.370 -14.297 9.531 1.00 9.36 ? 398 ILE A O 1 ATOM 2989 C CB . ILE A 1 396 ? 77.921 -11.862 10.039 1.00 9.45 ? 398 ILE A CB 1 ATOM 2990 C CG1 . ILE A 1 396 ? 77.098 -10.833 9.255 1.00 9.06 ? 398 ILE A CG1 1 ATOM 2991 C CG2 . ILE A 1 396 ? 79.133 -11.226 10.705 1.00 9.10 ? 398 ILE A CG2 1 ATOM 2992 C CD1 . ILE A 1 396 ? 76.244 -9.948 10.138 1.00 9.74 ? 398 ILE A CD1 1 ATOM 2993 N N . GLY A 1 397 ? 76.887 -13.895 7.385 1.00 9.62 ? 399 GLY A N 1 ATOM 2994 C CA . GLY A 1 397 ? 75.715 -14.595 6.867 1.00 10.38 ? 399 GLY A CA 1 ATOM 2995 C C . GLY A 1 397 ? 75.681 -16.058 7.268 1.00 10.41 ? 399 GLY A C 1 ATOM 2996 O O . GLY A 1 397 ? 76.694 -16.750 7.198 1.00 10.32 ? 399 GLY A O 1 ATOM 2997 N N . GLN A 1 398 ? 74.515 -16.528 7.704 1.00 11.44 ? 400 GLN A N 1 ATOM 2998 C CA . GLN A 1 398 ? 74.383 -17.897 8.198 1.00 12.22 ? 400 GLN A CA 1 ATOM 2999 C C . GLN A 1 398 ? 73.254 -18.653 7.499 1.00 13.60 ? 400 GLN A C 1 ATOM 3000 O O . GLN A 1 398 ? 72.220 -18.076 7.159 1.00 12.41 ? 400 GLN A O 1 ATOM 3001 C CB . GLN A 1 398 ? 74.184 -17.913 9.718 1.00 13.31 ? 400 GLN A CB 1 ATOM 3002 C CG . GLN A 1 398 ? 75.378 -17.380 10.498 1.00 12.99 ? 400 GLN A CG 1 ATOM 3003 C CD . GLN A 1 398 ? 75.266 -17.599 11.997 1.00 14.19 ? 400 GLN A CD 1 ATOM 3004 O OE1 . GLN A 1 398 ? 76.267 -17.835 12.674 1.00 15.67 ? 400 GLN A OE1 1 ATOM 3005 N NE2 . GLN A 1 398 ? 74.054 -17.487 12.528 1.00 13.91 ? 400 GLN A NE2 1 ATOM 3006 N N . ASN A 1 399 ? 73.483 -19.938 7.250 1.00 13.73 ? 401 ASN A N 1 ATOM 3007 C CA . ASN A 1 399 ? 72.437 -20.823 6.744 1.00 15.42 ? 401 ASN A CA 1 ATOM 3008 C C . ASN A 1 399 ? 72.579 -22.229 7.319 1.00 15.93 ? 401 ASN A C 1 ATOM 3009 O O . ASN A 1 399 ? 72.864 -23.183 6.593 1.00 16.20 ? 401 ASN A O 1 ATOM 3010 C CB . ASN A 1 399 ? 72.455 -20.870 5.213 1.00 16.48 ? 401 ASN A CB 1 ATOM 3011 C CG . ASN A 1 399 ? 71.228 -21.557 4.637 1.00 18.25 ? 401 ASN A CG 1 ATOM 3012 O OD1 . ASN A 1 399 ? 70.128 -21.458 5.187 1.00 20.53 ? 401 ASN A OD1 1 ATOM 3013 N ND2 . ASN A 1 399 ? 71.414 -22.268 3.534 1.00 17.38 ? 401 ASN A ND2 1 ATOM 3014 N N . ASN A 1 400 ? 72.447 -22.328 8.639 1.00 16.22 ? 402 ASN A N 1 ATOM 3015 C CA . ASN A 1 400 ? 72.460 -23.609 9.337 1.00 18.33 ? 402 ASN A CA 1 ATOM 3016 C C . ASN A 1 400 ? 73.663 -24.485 9.011 1.00 17.66 ? 402 ASN A C 1 ATOM 3017 O O . ASN A 1 400 ? 73.513 -25.661 8.689 1.00 18.57 ? 402 ASN A O 1 ATOM 3018 C CB . ASN A 1 400 ? 71.162 -24.373 9.081 1.00 19.43 ? 402 ASN A CB 1 ATOM 3019 C CG . ASN A 1 400 ? 69.954 -23.663 9.651 1.00 20.73 ? 402 ASN A CG 1 ATOM 3020 O OD1 . ASN A 1 400 ? 69.860 -23.448 10.861 1.00 23.18 ? 402 ASN A OD1 1 ATOM 3021 N ND2 . ASN A 1 400 ? 69.035 -23.266 8.780 1.00 23.67 ? 402 ASN A ND2 1 ATOM 3022 N N . GLY A 1 401 ? 74.855 -23.913 9.132 1.00 17.81 ? 403 GLY A N 1 ATOM 3023 C CA . GLY A 1 401 ? 76.091 -24.675 9.000 1.00 20.92 ? 403 GLY A CA 1 ATOM 3024 C C . GLY A 1 401 ? 76.510 -24.897 7.561 1.00 21.86 ? 403 GLY A C 1 ATOM 3025 O O . GLY A 1 401 ? 77.660 -25.247 7.289 1.00 25.28 ? 403 GLY A O 1 ATOM 3026 N N . GLN A 1 402 ? 75.577 -24.689 6.636 1.00 20.53 ? 404 GLN A N 1 ATOM 3027 C CA . GLN A 1 402 ? 75.844 -24.883 5.214 1.00 20.65 ? 404 GLN A CA 1 ATOM 3028 C C . GLN A 1 402 ? 76.741 -23.775 4.667 1.00 18.39 ? 404 GLN A C 1 ATOM 3029 O O . GLN A 1 402 ? 76.744 -22.660 5.186 1.00 16.37 ? 404 GLN A O 1 ATOM 3030 C CB . GLN A 1 402 ? 74.530 -24.924 4.430 1.00 22.35 ? 404 GLN A CB 1 ATOM 3031 C CG . GLN A 1 402 ? 73.652 -26.122 4.750 1.00 25.11 ? 404 GLN A CG 1 ATOM 3032 C CD . GLN A 1 402 ? 74.272 -27.433 4.307 1.00 28.51 ? 404 GLN A CD 1 ATOM 3033 O OE1 . GLN A 1 402 ? 74.313 -27.743 3.116 1.00 33.16 ? 404 GLN A OE1 1 ATOM 3034 N NE2 . GLN A 1 402 ? 74.764 -28.208 5.266 1.00 29.94 ? 404 GLN A NE2 1 ATOM 3035 N N . PRO A 1 403 ? 77.513 -24.081 3.614 1.00 17.27 ? 405 PRO A N 1 ATOM 3036 C CA . PRO A 1 403 ? 78.250 -23.016 2.936 1.00 16.23 ? 405 PRO A CA 1 ATOM 3037 C C . PRO A 1 403 ? 77.286 -21.930 2.465 1.00 14.53 ? 405 PRO A C 1 ATOM 3038 O O . PRO A 1 403 ? 76.148 -22.233 2.115 1.00 14.39 ? 405 PRO A O 1 ATOM 3039 C CB . PRO A 1 403 ? 78.877 -23.728 1.727 1.00 17.71 ? 405 PRO A CB 1 ATOM 3040 C CG . PRO A 1 403 ? 78.800 -25.190 2.032 1.00 18.43 ? 405 PRO A CG 1 ATOM 3041 C CD . PRO A 1 403 ? 77.578 -25.359 2.886 1.00 18.71 ? 405 PRO A CD 1 ATOM 3042 N N . ARG A 1 404 ? 77.723 -20.674 2.498 1.00 12.74 ? 406 ARG A N 1 ATOM 3043 C CA . ARG A 1 404 ? 76.877 -19.562 2.071 1.00 11.61 ? 406 ARG A CA 1 ATOM 3044 C C . ARG A 1 404 ? 77.066 -19.289 0.583 1.00 11.53 ? 406 ARG A C 1 ATOM 3045 O O . ARG A 1 404 ? 78.194 -19.254 0.089 1.00 11.09 ? 406 ARG A O 1 ATOM 3046 C CB . ARG A 1 404 ? 77.197 -18.297 2.876 1.00 11.40 ? 406 ARG A CB 1 ATOM 3047 C CG . ARG A 1 404 ? 76.849 -18.384 4.356 1.00 11.17 ? 406 ARG A CG 1 ATOM 3048 C CD . ARG A 1 404 ? 77.918 -19.110 5.164 1.00 11.44 ? 406 ARG A CD 1 ATOM 3049 N NE . ARG A 1 404 ? 79.282 -18.702 4.820 1.00 11.45 ? 406 ARG A NE 1 ATOM 3050 C CZ . ARG A 1 404 ? 79.790 -17.493 5.039 1.00 11.87 ? 406 ARG A CZ 1 ATOM 3051 N NH1 . ARG A 1 404 ? 79.045 -16.538 5.587 1.00 11.28 ? 406 ARG A NH1 1 ATOM 3052 N NH2 . ARG A 1 404 ? 81.047 -17.234 4.700 1.00 11.61 ? 406 ARG A NH2 1 ATOM 3053 N N . VAL A 1 405 ? 75.959 -19.134 -0.134 1.00 10.79 ? 407 VAL A N 1 ATOM 3054 C CA . VAL A 1 405 ? 76.021 -18.719 -1.530 1.00 10.63 ? 407 VAL A CA 1 ATOM 3055 C C . VAL A 1 405 ? 76.026 -17.200 -1.611 1.00 10.23 ? 407 VAL A C 1 ATOM 3056 O O . VAL A 1 405 ? 75.079 -16.543 -1.181 1.00 10.40 ? 407 VAL A O 1 ATOM 3057 C CB . VAL A 1 405 ? 74.842 -19.281 -2.346 1.00 11.51 ? 407 VAL A CB 1 ATOM 3058 C CG1 . VAL A 1 405 ? 74.900 -18.776 -3.780 1.00 12.32 ? 407 VAL A CG1 1 ATOM 3059 C CG2 . VAL A 1 405 ? 74.852 -20.804 -2.309 1.00 11.94 ? 407 VAL A CG2 1 ATOM 3060 N N . VAL A 1 406 ? 77.120 -16.647 -2.119 1.00 9.99 ? 408 VAL A N 1 ATOM 3061 C CA . VAL A 1 406 ? 77.301 -15.202 -2.163 1.00 9.92 ? 408 VAL A CA 1 ATOM 3062 C C . VAL A 1 406 ? 77.603 -14.749 -3.587 1.00 10.24 ? 408 VAL A C 1 ATOM 3063 O O . VAL A 1 406 ? 78.548 -15.228 -4.219 1.00 9.87 ? 408 VAL A O 1 ATOM 3064 C CB . VAL A 1 406 ? 78.436 -14.751 -1.222 1.00 9.81 ? 408 VAL A CB 1 ATOM 3065 C CG1 . VAL A 1 406 ? 78.484 -13.230 -1.125 1.00 9.53 ? 408 VAL A CG1 1 ATOM 3066 C CG2 . VAL A 1 406 ? 78.262 -15.372 0.157 1.00 9.44 ? 408 VAL A CG2 1 ATOM 3067 N N . ASN A 1 407 ? 76.779 -13.844 -4.104 1.00 10.65 ? 409 ASN A N 1 ATOM 3068 C CA . ASN A 1 407 ? 76.948 -13.366 -5.471 1.00 10.97 ? 409 ASN A CA 1 ATOM 3069 C C . ASN A 1 407 ? 77.560 -11.970 -5.523 1.00 10.67 ? 409 ASN A C 1 ATOM 3070 O O . ASN A 1 407 ? 77.572 -11.248 -4.526 1.00 9.77 ? 409 ASN A O 1 ATOM 3071 C CB . ASN A 1 407 ? 75.610 -13.383 -6.211 1.00 11.88 ? 409 ASN A CB 1 ATOM 3072 C CG . ASN A 1 407 ? 75.003 -14.771 -6.284 1.00 13.27 ? 409 ASN A CG 1 ATOM 3073 O OD1 . ASN A 1 407 ? 73.786 -14.925 -6.406 1.00 15.94 ? 409 ASN A OD1 1 ATOM 3074 N ND2 . ASN A 1 407 ? 75.849 -15.789 -6.226 1.00 12.59 ? 409 ASN A ND2 1 ATOM 3075 N N . GLY A 1 408 ? 78.098 -11.608 -6.682 1.00 10.15 ? 410 GLY A N 1 ATOM 3076 C CA . GLY A 1 408 ? 78.528 -10.233 -6.915 1.00 10.30 ? 410 GLY A CA 1 ATOM 3077 C C . GLY A 1 408 ? 79.973 -9.944 -6.551 1.00 10.68 ? 410 GLY A C 1 ATOM 3078 O O . GLY A 1 408 ? 80.476 -8.857 -6.837 1.00 10.25 ? 410 GLY A O 1 ATOM 3079 N N . LEU A 1 409 ? 80.656 -10.918 -5.953 1.00 10.36 ? 411 LEU A N 1 ATOM 3080 C CA . LEU A 1 409 ? 81.992 -10.684 -5.391 1.00 10.74 ? 411 LEU A CA 1 ATOM 3081 C C . LEU A 1 409 ? 83.059 -10.476 -6.464 1.00 11.40 ? 411 LEU A C 1 ATOM 3082 O O . LEU A 1 409 ? 84.047 -9.770 -6.242 1.00 11.74 ? 411 LEU A O 1 ATOM 3083 C CB . LEU A 1 409 ? 82.411 -11.837 -4.476 1.00 10.69 ? 411 LEU A CB 1 ATOM 3084 C CG . LEU A 1 409 ? 81.634 -12.016 -3.170 1.00 10.53 ? 411 LEU A CG 1 ATOM 3085 C CD1 . LEU A 1 409 ? 82.167 -13.215 -2.394 1.00 10.48 ? 411 LEU A CD1 1 ATOM 3086 C CD2 . LEU A 1 409 ? 81.691 -10.755 -2.319 1.00 10.11 ? 411 LEU A CD2 1 ATOM 3087 N N . LEU A 1 410 ? 82.871 -11.118 -7.613 1.00 11.50 ? 412 LEU A N 1 ATOM 3088 C CA . LEU A 1 410 ? 83.857 -11.088 -8.686 1.00 12.33 ? 412 LEU A CA 1 ATOM 3089 C C . LEU A 1 410 ? 83.544 -9.977 -9.683 1.00 12.85 ? 412 LEU A C 1 ATOM 3090 O O . LEU A 1 410 ? 82.535 -10.033 -10.385 1.00 12.27 ? 412 LEU A O 1 ATOM 3091 C CB . LEU A 1 410 ? 83.898 -12.438 -9.406 1.00 12.78 ? 412 LEU A CB 1 ATOM 3092 C CG . LEU A 1 410 ? 84.248 -13.658 -8.550 1.00 13.14 ? 412 LEU A CG 1 ATOM 3093 C CD1 . LEU A 1 410 ? 84.263 -14.919 -9.398 1.00 14.50 ? 412 LEU A CD1 1 ATOM 3094 C CD2 . LEU A 1 410 ? 85.589 -13.465 -7.856 1.00 13.39 ? 412 LEU A CD2 1 ATOM 3095 N N . PRO A 1 411 ? 84.427 -8.971 -9.764 1.00 13.78 ? 413 PRO A N 1 ATOM 3096 C CA . PRO A 1 411 ? 84.188 -7.770 -10.560 1.00 14.22 ? 413 PRO A CA 1 ATOM 3097 C C . PRO A 1 411 ? 83.819 -8.049 -12.019 1.00 14.38 ? 413 PRO A C 1 ATOM 3098 O O . PRO A 1 411 ? 83.012 -7.321 -12.597 1.00 14.40 ? 413 PRO A O 1 ATOM 3099 C CB . PRO A 1 411 ? 85.529 -7.034 -10.476 1.00 14.53 ? 413 PRO A CB 1 ATOM 3100 C CG . PRO A 1 411 ? 86.065 -7.431 -9.144 1.00 14.00 ? 413 PRO A CG 1 ATOM 3101 C CD . PRO A 1 411 ? 85.681 -8.879 -8.997 1.00 13.85 ? 413 PRO A CD 1 ATOM 3102 N N . SER A 1 412 ? 84.371 -9.113 -12.597 1.00 14.07 ? 414 SER A N 1 ATOM 3103 C CA . SER A 1 412 ? 84.218 -9.361 -14.033 1.00 14.70 ? 414 SER A CA 1 ATOM 3104 C C . SER A 1 412 ? 82.874 -9.990 -14.417 1.00 14.93 ? 414 SER A C 1 ATOM 3105 O O . SER A 1 412 ? 82.514 -10.027 -15.593 1.00 14.52 ? 414 SER A O 1 ATOM 3106 C CB . SER A 1 412 ? 85.369 -10.224 -14.556 1.00 15.07 ? 414 SER A CB 1 ATOM 3107 O OG . SER A 1 412 ? 85.266 -11.548 -14.071 1.00 16.36 ? 414 SER A OG 1 ATOM 3108 N N . ASN A 1 413 ? 82.146 -10.494 -13.426 1.00 13.79 ? 415 ASN A N 1 ATOM 3109 C CA . ASN A 1 413 ? 80.865 -11.159 -13.663 1.00 13.26 ? 415 ASN A CA 1 ATOM 3110 C C . ASN A 1 413 ? 80.024 -11.161 -12.393 1.00 13.44 ? 415 ASN A C 1 ATOM 3111 O O . ASN A 1 413 ? 80.223 -11.995 -11.511 1.00 12.44 ? 415 ASN A O 1 ATOM 3112 C CB . ASN A 1 413 ? 81.092 -12.598 -14.142 1.00 14.15 ? 415 ASN A CB 1 ATOM 3113 C CG . ASN A 1 413 ? 79.796 -13.325 -14.455 1.00 15.28 ? 415 ASN A CG 1 ATOM 3114 O OD1 . ASN A 1 413 ? 78.707 -12.760 -14.344 1.00 14.35 ? 415 ASN A OD1 1 ATOM 3115 N ND2 . ASN A 1 413 ? 79.910 -14.591 -14.852 1.00 17.42 ? 415 ASN A ND2 1 ATOM 3116 N N . SER A 1 414 ? 79.099 -10.211 -12.298 1.00 13.20 ? 416 SER A N 1 ATOM 3117 C CA . SER A 1 414 ? 78.308 -10.030 -11.087 1.00 14.06 ? 416 SER A CA 1 ATOM 3118 C C . SER A 1 414 ? 77.347 -11.187 -10.862 1.00 13.30 ? 416 SER A C 1 ATOM 3119 O O . SER A 1 414 ? 76.797 -11.340 -9.773 1.00 14.65 ? 416 SER A O 1 ATOM 3120 C CB . SER A 1 414 ? 77.542 -8.704 -11.128 1.00 14.33 ? 416 SER A CB 1 ATOM 3121 O OG . SER A 1 414 ? 76.490 -8.740 -12.082 1.00 14.76 ? 416 SER A OG 1 ATOM 3122 N N . SER A 1 415 ? 77.163 -12.012 -11.888 1.00 13.39 ? 417 SER A N 1 ATOM 3123 C CA . SER A 1 415 ? 76.316 -13.191 -11.765 1.00 13.77 ? 417 SER A CA 1 ATOM 3124 C C . SER A 1 415 ? 77.058 -14.373 -11.153 1.00 13.77 ? 417 SER A C 1 ATOM 3125 O O . SER A 1 415 ? 76.438 -15.356 -10.758 1.00 14.22 ? 417 SER A O 1 ATOM 3126 C CB . SER A 1 415 ? 75.731 -13.584 -13.123 1.00 13.52 ? 417 SER A CB 1 ATOM 3127 O OG . SER A 1 415 ? 74.802 -12.615 -13.570 1.00 14.25 ? 417 SER A OG 1 ATOM 3128 N N . ALA A 1 416 ? 78.383 -14.285 -11.085 1.00 13.54 ? 418 ALA A N 1 ATOM 3129 C CA . ALA A 1 416 ? 79.186 -15.406 -10.598 1.00 14.11 ? 418 ALA A CA 1 ATOM 3130 C C . ALA A 1 416 ? 78.973 -15.636 -9.102 1.00 14.32 ? 418 ALA A C 1 ATOM 3131 O O . ALA A 1 416 ? 79.129 -14.716 -8.296 1.00 14.32 ? 418 ALA A O 1 ATOM 3132 C CB . ALA A 1 416 ? 80.659 -15.182 -10.900 1.00 13.85 ? 418 ALA A CB 1 ATOM 3133 N N . SER A 1 417 ? 78.617 -16.866 -8.742 1.00 13.70 ? 419 SER A N 1 ATOM 3134 C CA . SER A 1 417 ? 78.375 -17.238 -7.351 1.00 14.11 ? 419 SER A CA 1 ATOM 3135 C C . SER A 1 417 ? 79.637 -17.799 -6.712 1.00 13.46 ? 419 SER A C 1 ATOM 3136 O O . SER A 1 417 ? 80.403 -18.510 -7.357 1.00 13.52 ? 419 SER A O 1 ATOM 3137 C CB . SER A 1 417 ? 77.273 -18.302 -7.267 1.00 15.40 ? 419 SER A CB 1 ATOM 3138 O OG . SER A 1 417 ? 75.993 -17.742 -7.488 1.00 16.04 ? 419 SER A OG 1 ATOM 3139 N N . LEU A 1 418 ? 79.824 -17.516 -5.429 1.00 13.61 ? 420 LEU A N 1 ATOM 3140 C CA . LEU A 1 418 ? 80.778 -18.266 -4.623 1.00 13.26 ? 420 LEU A CA 1 ATOM 3141 C C . LEU A 1 418 ? 80.054 -18.999 -3.505 1.00 13.52 ? 420 LEU A C 1 ATOM 3142 O O . LEU A 1 418 ? 79.125 -18.465 -2.893 1.00 12.61 ? 420 LEU A O 1 ATOM 3143 C CB . LEU A 1 418 ? 81.856 -17.345 -4.043 1.00 13.83 ? 420 LEU A CB 1 ATOM 3144 C CG . LEU A 1 418 ? 82.885 -16.777 -5.023 1.00 13.99 ? 420 LEU A CG 1 ATOM 3145 C CD1 . LEU A 1 418 ? 83.992 -16.045 -4.278 1.00 14.46 ? 420 LEU A CD1 1 ATOM 3146 C CD2 . LEU A 1 418 ? 83.456 -17.881 -5.897 1.00 14.31 ? 420 LEU A CD2 1 ATOM 3147 N N . SER A 1 419 ? 80.454 -20.243 -3.277 1.00 13.28 ? 421 SER A N 1 ATOM 3148 C CA . SER A 1 419 ? 79.935 -21.023 -2.166 1.00 13.88 ? 421 SER A CA 1 ATOM 3149 C C . SER A 1 419 ? 80.963 -21.020 -1.045 1.00 13.96 ? 421 SER A C 1 ATOM 3150 O O . SER A 1 419 ? 82.044 -21.585 -1.187 1.00 14.48 ? 421 SER A O 1 ATOM 3151 C CB . SER A 1 419 ? 79.651 -22.455 -2.615 1.00 15.66 ? 421 SER A CB 1 ATOM 3152 O OG . SER A 1 419 ? 79.206 -23.243 -1.527 1.00 17.58 ? 421 SER A OG 1 ATOM 3153 N N . ILE A 1 420 ? 80.649 -20.331 0.045 1.00 12.52 ? 422 ILE A N 1 ATOM 3154 C CA . ILE A 1 420 ? 81.662 -19.980 1.032 1.00 11.89 ? 422 ILE A CA 1 ATOM 3155 C C . ILE A 1 420 ? 81.357 -20.622 2.380 1.00 11.59 ? 422 ILE A C 1 ATOM 3156 O O . ILE A 1 420 ? 80.274 -20.430 2.932 1.00 11.82 ? 422 ILE A O 1 ATOM 3157 C CB . ILE A 1 420 ? 81.766 -18.453 1.204 1.00 11.53 ? 422 ILE A CB 1 ATOM 3158 C CG1 . ILE A 1 420 ? 81.698 -17.758 -0.160 1.00 11.14 ? 422 ILE A CG1 1 ATOM 3159 C CG2 . ILE A 1 420 ? 83.050 -18.083 1.930 1.00 11.60 ? 422 ILE A CG2 1 ATOM 3160 C CD1 . ILE A 1 420 ? 81.979 -16.271 -0.100 1.00 10.65 ? 422 ILE A CD1 1 ATOM 3161 N N . PRO A 1 421 ? 82.304 -21.416 2.900 1.00 12.00 ? 423 PRO A N 1 ATOM 3162 C CA . PRO A 1 421 ? 82.190 -21.938 4.258 1.00 12.58 ? 423 PRO A CA 1 ATOM 3163 C C . PRO A 1 421 ? 82.147 -20.786 5.247 1.00 13.19 ? 423 PRO A C 1 ATOM 3164 O O . PRO A 1 421 ? 82.663 -19.705 4.959 1.00 13.06 ? 423 PRO A O 1 ATOM 3165 C CB . PRO A 1 421 ? 83.490 -22.736 4.444 1.00 13.03 ? 423 PRO A CB 1 ATOM 3166 C CG . PRO A 1 421 ? 84.009 -22.977 3.068 1.00 13.82 ? 423 PRO A CG 1 ATOM 3167 C CD . PRO A 1 421 ? 83.577 -21.788 2.265 1.00 12.60 ? 423 PRO A CD 1 ATOM 3168 N N . GLN A 1 422 ? 81.529 -21.007 6.402 1.00 14.41 ? 424 GLN A N 1 ATOM 3169 C CA . GLN A 1 422 ? 81.561 -20.011 7.460 1.00 14.57 ? 424 GLN A CA 1 ATOM 3170 C C . GLN A 1 422 ? 83.004 -19.748 7.886 1.00 14.67 ? 424 GLN A C 1 ATOM 3171 O O . GLN A 1 422 ? 83.764 -20.687 8.128 1.00 15.78 ? 424 GLN A O 1 ATOM 3172 C CB . GLN A 1 422 ? 80.734 -20.476 8.658 1.00 15.57 ? 424 GLN A CB 1 ATOM 3173 C CG . GLN A 1 422 ? 79.231 -20.389 8.450 1.00 16.01 ? 424 GLN A CG 1 ATOM 3174 C CD . GLN A 1 422 ? 78.460 -20.546 9.746 1.00 17.81 ? 424 GLN A CD 1 ATOM 3175 O OE1 . GLN A 1 422 ? 78.885 -20.061 10.795 1.00 18.66 ? 424 GLN A OE1 1 ATOM 3176 N NE2 . GLN A 1 422 ? 77.321 -21.224 9.680 1.00 16.19 ? 424 GLN A NE2 1 ATOM 3177 N N . PHE A 1 423 ? 83.380 -18.473 7.943 1.00 14.07 ? 425 PHE A N 1 ATOM 3178 C CA . PHE A 1 423 ? 84.655 -18.058 8.530 1.00 14.30 ? 425 PHE A CA 1 ATOM 3179 C C . PHE A 1 423 ? 84.434 -17.539 9.942 1.00 12.89 ? 425 PHE A C 1 ATOM 3180 O O . PHE A 1 423 ? 85.383 -17.339 10.697 1.00 11.69 ? 425 PHE A O 1 ATOM 3181 C CB . PHE A 1 423 ? 85.291 -16.946 7.699 1.00 15.87 ? 425 PHE A CB 1 ATOM 3182 C CG . PHE A 1 423 ? 85.459 -17.289 6.250 1.00 17.77 ? 425 PHE A CG 1 ATOM 3183 C CD1 . PHE A 1 423 ? 86.099 -18.455 5.874 1.00 18.34 ? 425 PHE A CD1 1 ATOM 3184 C CD2 . PHE A 1 423 ? 85.022 -16.416 5.264 1.00 20.42 ? 425 PHE A CD2 1 ATOM 3185 C CE1 . PHE A 1 423 ? 86.268 -18.770 4.538 1.00 18.66 ? 425 PHE A CE1 1 ATOM 3186 C CE2 . PHE A 1 423 ? 85.200 -16.716 3.927 1.00 20.11 ? 425 PHE A CE2 1 ATOM 3187 C CZ . PHE A 1 423 ? 85.828 -17.894 3.564 1.00 19.38 ? 425 PHE A CZ 1 ATOM 3188 N N . VAL A 1 424 ? 83.178 -17.243 10.254 1.00 12.46 ? 426 VAL A N 1 ATOM 3189 C CA . VAL A 1 424 ? 82.796 -16.784 11.581 1.00 11.89 ? 426 VAL A CA 1 ATOM 3190 C C . VAL A 1 424 ? 81.844 -17.801 12.196 1.00 12.40 ? 426 VAL A C 1 ATOM 3191 O O . VAL A 1 424 ? 80.850 -18.180 11.578 1.00 13.16 ? 426 VAL A O 1 ATOM 3192 C CB . VAL A 1 424 ? 82.085 -15.420 11.512 1.00 11.78 ? 426 VAL A CB 1 ATOM 3193 C CG1 . VAL A 1 424 ? 81.555 -15.028 12.883 1.00 13.17 ? 426 VAL A CG1 1 ATOM 3194 C CG2 . VAL A 1 424 ? 83.034 -14.357 10.981 1.00 12.07 ? 426 VAL A CG2 1 ATOM 3195 N N . VAL A 1 425 ? 82.163 -18.252 13.404 1.00 11.53 ? 427 VAL A N 1 ATOM 3196 C CA . VAL A 1 425 ? 81.376 -19.280 14.066 1.00 10.89 ? 427 VAL A CA 1 ATOM 3197 C C . VAL A 1 425 ? 80.818 -18.721 15.366 1.00 11.03 ? 427 VAL A C 1 ATOM 3198 O O . VAL A 1 425 ? 81.574 -18.310 16.249 1.00 10.20 ? 427 VAL A O 1 ATOM 3199 C CB . VAL A 1 425 ? 82.228 -20.530 14.370 1.00 11.18 ? 427 VAL A CB 1 ATOM 3200 C CG1 . VAL A 1 425 ? 81.414 -21.558 15.143 1.00 11.40 ? 427 VAL A CG1 1 ATOM 3201 C CG2 . VAL A 1 425 ? 82.768 -21.133 13.078 1.00 12.11 ? 427 VAL A CG2 1 ATOM 3202 N N . SER A 1 426 ? 79.494 -18.637 15.450 1.00 11.41 ? 428 SER A N 1 ATOM 3203 C CA . SER A 1 426 ? 78.851 -18.180 16.671 1.00 10.84 ? 428 SER A CA 1 ATOM 3204 C C . SER A 1 426 ? 79.005 -19.197 17.786 1.00 10.78 ? 428 SER A C 1 ATOM 3205 O O . SER A 1 426 ? 78.618 -20.357 17.646 1.00 11.55 ? 428 SER A O 1 ATOM 3206 C CB . SER A 1 426 ? 77.368 -17.888 16.447 1.00 10.84 ? 428 SER A CB 1 ATOM 3207 O OG . SER A 1 426 ? 76.746 -17.535 17.674 1.00 10.59 ? 428 SER A OG 1 ATOM 3208 N N . HIS A 1 427 ? 79.552 -18.748 18.905 1.00 11.17 ? 429 HIS A N 1 ATOM 3209 C CA . HIS A 1 427 ? 79.508 -19.526 20.131 1.00 12.01 ? 429 HIS A CA 1 ATOM 3210 C C . HIS A 1 427 ? 78.486 -18.929 21.083 1.00 11.27 ? 429 HIS A C 1 ATOM 3211 O O . HIS A 1 427 ? 78.506 -19.190 22.285 1.00 10.63 ? 429 HIS A O 1 ATOM 3212 C CB . HIS A 1 427 ? 80.895 -19.602 20.767 1.00 13.13 ? 429 HIS A CB 1 ATOM 3213 C CG . HIS A 1 427 ? 81.895 -20.332 19.925 1.00 14.26 ? 429 HIS A CG 1 ATOM 3214 N ND1 . HIS A 1 427 ? 81.667 -21.600 19.436 1.00 17.31 ? 429 HIS A ND1 1 ATOM 3215 C CD2 . HIS A 1 427 ? 83.086 -19.942 19.415 1.00 15.46 ? 429 HIS A CD2 1 ATOM 3216 C CE1 . HIS A 1 427 ? 82.694 -21.977 18.695 1.00 17.63 ? 429 HIS A CE1 1 ATOM 3217 N NE2 . HIS A 1 427 ? 83.569 -20.988 18.666 1.00 15.42 ? 429 HIS A NE2 1 ATOM 3218 N N . GLY A 1 428 ? 77.580 -18.137 20.517 1.00 11.06 ? 430 GLY A N 1 ATOM 3219 C CA . GLY A 1 428 ? 76.418 -17.653 21.235 1.00 10.86 ? 430 GLY A CA 1 ATOM 3220 C C . GLY A 1 428 ? 76.721 -16.415 22.048 1.00 11.50 ? 430 GLY A C 1 ATOM 3221 O O . GLY A 1 428 ? 77.736 -15.744 21.833 1.00 11.27 ? 430 GLY A O 1 ATOM 3222 N N . GLY A 1 429 ? 75.864 -16.147 23.025 1.00 10.74 ? 431 GLY A N 1 ATOM 3223 C CA . GLY A 1 429 ? 75.919 -14.903 23.778 1.00 10.39 ? 431 GLY A CA 1 ATOM 3224 C C . GLY A 1 429 ? 74.623 -14.681 24.526 1.00 10.41 ? 431 GLY A C 1 ATOM 3225 O O . GLY A 1 429 ? 73.850 -15.614 24.744 1.00 10.07 ? 431 GLY A O 1 ATOM 3226 N N . GLU A 1 430 ? 74.379 -13.439 24.921 1.00 10.34 ? 432 GLU A N 1 ATOM 3227 C CA . GLU A 1 430 ? 73.169 -13.115 25.649 1.00 10.42 ? 432 GLU A CA 1 ATOM 3228 C C . GLU A 1 430 ? 72.765 -11.681 25.345 1.00 10.07 ? 432 GLU A C 1 ATOM 3229 O O . GLU A 1 430 ? 73.576 -10.890 24.843 1.00 9.54 ? 432 GLU A O 1 ATOM 3230 C CB . GLU A 1 430 ? 73.378 -13.327 27.154 1.00 10.68 ? 432 GLU A CB 1 ATOM 3231 C CG . GLU A 1 430 ? 72.124 -13.186 28.010 1.00 11.66 ? 432 GLU A CG 1 ATOM 3232 C CD . GLU A 1 430 ? 70.932 -13.963 27.471 1.00 12.44 ? 432 GLU A CD 1 ATOM 3233 O OE1 . GLU A 1 430 ? 70.223 -13.438 26.586 1.00 12.16 ? 432 GLU A OE1 1 ATOM 3234 O OE2 . GLU A 1 430 ? 70.657 -15.068 27.988 1.00 13.45 ? 432 GLU A OE2 1 ATOM 3235 N N . TYR A 1 431 ? 71.484 -11.392 25.550 1.00 9.09 ? 433 TYR A N 1 ATOM 3236 C CA . TYR A 1 431 ? 70.975 -10.029 25.517 1.00 9.10 ? 433 TYR A CA 1 ATOM 3237 C C . TYR A 1 431 ? 70.913 -9.464 26.930 1.00 8.66 ? 433 TYR A C 1 ATOM 3238 O O . TYR A 1 431 ? 70.335 -10.080 27.825 1.00 8.54 ? 433 TYR A O 1 ATOM 3239 C CB . TYR A 1 431 ? 69.575 -10.002 24.901 1.00 8.81 ? 433 TYR A CB 1 ATOM 3240 C CG . TYR A 1 431 ? 69.508 -10.485 23.467 1.00 8.74 ? 433 TYR A CG 1 ATOM 3241 C CD1 . TYR A 1 431 ? 70.477 -10.119 22.539 1.00 9.10 ? 433 TYR A CD1 1 ATOM 3242 C CD2 . TYR A 1 431 ? 68.448 -11.268 23.031 1.00 8.90 ? 433 TYR A CD2 1 ATOM 3243 C CE1 . TYR A 1 431 ? 70.400 -10.537 21.220 1.00 8.96 ? 433 TYR A CE1 1 ATOM 3244 C CE2 . TYR A 1 431 ? 68.359 -11.688 21.716 1.00 8.98 ? 433 TYR A CE2 1 ATOM 3245 C CZ . TYR A 1 431 ? 69.341 -11.328 20.817 1.00 8.94 ? 433 TYR A CZ 1 ATOM 3246 O OH . TYR A 1 431 ? 69.246 -11.750 19.509 1.00 9.38 ? 433 TYR A OH 1 ATOM 3247 N N . PHE A 1 432 ? 71.502 -8.286 27.121 1.00 8.74 ? 434 PHE A N 1 ATOM 3248 C CA . PHE A 1 432 ? 71.500 -7.627 28.426 1.00 8.96 ? 434 PHE A CA 1 ATOM 3249 C C . PHE A 1 432 ? 70.855 -6.247 28.327 1.00 8.97 ? 434 PHE A C 1 ATOM 3250 O O . PHE A 1 432 ? 70.668 -5.714 27.232 1.00 9.06 ? 434 PHE A O 1 ATOM 3251 C CB . PHE A 1 432 ? 72.929 -7.476 28.959 1.00 8.69 ? 434 PHE A CB 1 ATOM 3252 C CG . PHE A 1 432 ? 73.665 -8.780 29.119 1.00 9.06 ? 434 PHE A CG 1 ATOM 3253 C CD1 . PHE A 1 432 ? 74.411 -9.300 28.077 1.00 9.20 ? 434 PHE A CD1 1 ATOM 3254 C CD2 . PHE A 1 432 ? 73.654 -9.455 30.331 1.00 9.01 ? 434 PHE A CD2 1 ATOM 3255 C CE1 . PHE A 1 432 ? 75.116 -10.482 28.230 1.00 9.38 ? 434 PHE A CE1 1 ATOM 3256 C CE2 . PHE A 1 432 ? 74.348 -10.643 30.491 1.00 9.25 ? 434 PHE A CE2 1 ATOM 3257 C CZ . PHE A 1 432 ? 75.082 -11.158 29.438 1.00 9.02 ? 434 PHE A CZ 1 ATOM 3258 N N . PHE A 1 433 ? 70.507 -5.681 29.478 1.00 9.24 ? 435 PHE A N 1 ATOM 3259 C CA . PHE A 1 433 ? 70.142 -4.271 29.557 1.00 9.43 ? 435 PHE A CA 1 ATOM 3260 C C . PHE A 1 433 ? 71.159 -3.511 30.397 1.00 9.32 ? 435 PHE A C 1 ATOM 3261 O O . PHE A 1 433 ? 71.337 -3.802 31.580 1.00 8.60 ? 435 PHE A O 1 ATOM 3262 C CB . PHE A 1 433 ? 68.748 -4.107 30.161 1.00 9.66 ? 435 PHE A CB 1 ATOM 3263 C CG . PHE A 1 433 ? 68.276 -2.682 30.208 1.00 9.64 ? 435 PHE A CG 1 ATOM 3264 C CD1 . PHE A 1 433 ? 68.037 -1.983 29.036 1.00 9.58 ? 435 PHE A CD1 1 ATOM 3265 C CD2 . PHE A 1 433 ? 68.110 -2.032 31.419 1.00 9.83 ? 435 PHE A CD2 1 ATOM 3266 C CE1 . PHE A 1 433 ? 67.616 -0.666 29.072 1.00 9.93 ? 435 PHE A CE1 1 ATOM 3267 C CE2 . PHE A 1 433 ? 67.697 -0.714 31.462 1.00 9.74 ? 435 PHE A CE2 1 ATOM 3268 C CZ . PHE A 1 433 ? 67.454 -0.030 30.287 1.00 10.06 ? 435 PHE A CZ 1 ATOM 3269 N N . SER A 1 434 ? 71.846 -2.561 29.771 1.00 9.79 ? 436 SER A N 1 ATOM 3270 C CA . SER A 1 434 ? 72.719 -1.652 30.498 1.00 9.97 ? 436 SER A CA 1 ATOM 3271 C C . SER A 1 434 ? 71.895 -0.481 30.998 1.00 9.52 ? 436 SER A C 1 ATOM 3272 O O . SER A 1 434 ? 71.429 0.337 30.208 1.00 8.82 ? 436 SER A O 1 ATOM 3273 C CB . SER A 1 434 ? 73.846 -1.143 29.600 1.00 10.93 ? 436 SER A CB 1 ATOM 3274 O OG . SER A 1 434 ? 74.578 -2.219 29.040 1.00 13.88 ? 436 SER A OG 1 ATOM 3275 N N . PRO A 1 435 ? 71.642 -0.442 32.310 1.00 9.66 ? 437 PRO A N 1 ATOM 3276 C CA . PRO A 1 435 ? 70.774 0.589 32.855 1.00 9.23 ? 437 PRO A CA 1 ATOM 3277 C C . PRO A 1 435 ? 71.501 1.924 32.923 1.00 9.49 ? 437 PRO A C 1 ATOM 3278 O O . PRO A 1 435 ? 72.730 1.960 32.868 1.00 8.79 ? 437 PRO A O 1 ATOM 3279 C CB . PRO A 1 435 ? 70.469 0.077 34.263 1.00 9.69 ? 437 PRO A CB 1 ATOM 3280 C CG . PRO A 1 435 ? 71.657 -0.745 34.626 1.00 10.09 ? 437 PRO A CG 1 ATOM 3281 C CD . PRO A 1 435 ? 72.170 -1.346 33.346 1.00 9.63 ? 437 PRO A CD 1 ATOM 3282 N N . PRO A 1 436 ? 70.744 3.025 33.017 1.00 9.34 ? 438 PRO A N 1 ATOM 3283 C CA . PRO A 1 436 ? 71.350 4.297 33.392 1.00 9.73 ? 438 PRO A CA 1 ATOM 3284 C C . PRO A 1 436 ? 71.992 4.178 34.769 1.00 10.20 ? 438 PRO A C 1 ATOM 3285 O O . PRO A 1 436 ? 71.559 3.367 35.584 1.00 10.04 ? 438 PRO A O 1 ATOM 3286 C CB . PRO A 1 436 ? 70.156 5.254 33.448 1.00 9.46 ? 438 PRO A CB 1 ATOM 3287 C CG . PRO A 1 436 ? 68.983 4.377 33.727 1.00 9.88 ? 438 PRO A CG 1 ATOM 3288 C CD . PRO A 1 436 ? 69.272 3.070 33.043 1.00 9.70 ? 438 PRO A CD 1 ATOM 3289 N N . ILE A 1 437 ? 73.024 4.972 35.023 1.00 10.79 ? 439 ILE A N 1 ATOM 3290 C CA . ILE A 1 437 ? 73.807 4.808 36.239 1.00 11.23 ? 439 ILE A CA 1 ATOM 3291 C C . ILE A 1 437 ? 72.957 5.023 37.488 1.00 11.86 ? 439 ILE A C 1 ATOM 3292 O O . ILE A 1 437 ? 73.115 4.320 38.487 1.00 12.33 ? 439 ILE A O 1 ATOM 3293 C CB . ILE A 1 437 ? 75.039 5.734 36.242 1.00 11.43 ? 439 ILE A CB 1 ATOM 3294 C CG1 . ILE A 1 437 ? 75.961 5.367 35.075 1.00 11.67 ? 439 ILE A CG1 1 ATOM 3295 C CG2 . ILE A 1 437 ? 75.780 5.626 37.566 1.00 12.01 ? 439 ILE A CG2 1 ATOM 3296 C CD1 . ILE A 1 437 ? 77.003 6.417 34.740 1.00 11.40 ? 439 ILE A CD1 1 ATOM 3297 N N . SER A 1 438 ? 72.000 5.942 37.392 1.00 12.45 ? 440 SER A N 1 ATOM 3298 C CA . SER A 1 438 ? 71.096 6.245 38.496 1.00 12.41 ? 440 SER A CA 1 ATOM 3299 C C . SER A 1 438 ? 70.309 5.025 38.966 1.00 12.24 ? 440 SER A C 1 ATOM 3300 O O . SER A 1 438 ? 69.964 4.922 40.138 1.00 12.17 ? 440 SER A O 1 ATOM 3301 C CB . SER A 1 438 ? 70.136 7.373 38.108 1.00 13.15 ? 440 SER A CB 1 ATOM 3302 O OG . SER A 1 438 ? 69.450 7.059 36.907 1.00 14.04 ? 440 SER A OG 1 ATOM 3303 N N . ALA A 1 439 ? 70.057 4.086 38.060 1.00 11.87 ? 441 ALA A N 1 ATOM 3304 C CA . ALA A 1 439 ? 69.243 2.915 38.386 1.00 11.90 ? 441 ALA A CA 1 ATOM 3305 C C . ALA A 1 439 ? 70.038 1.859 39.155 1.00 12.03 ? 441 ALA A C 1 ATOM 3306 O O . ALA A 1 439 ? 69.463 1.018 39.843 1.00 12.33 ? 441 ALA A O 1 ATOM 3307 C CB . ALA A 1 439 ? 68.647 2.314 37.119 1.00 11.72 ? 441 ALA A CB 1 ATOM 3308 N N . ILE A 1 440 ? 71.361 1.906 39.035 1.00 12.47 ? 442 ILE A N 1 ATOM 3309 C CA . ILE A 1 440 ? 72.213 0.867 39.603 1.00 12.51 ? 442 ILE A CA 1 ATOM 3310 C C . ILE A 1 440 ? 72.179 0.901 41.129 1.00 13.41 ? 442 ILE A C 1 ATOM 3311 O O . ILE A 1 440 ? 71.861 -0.102 41.774 1.00 14.14 ? 442 ILE A O 1 ATOM 3312 C CB . ILE A 1 440 ? 73.662 0.977 39.088 1.00 12.77 ? 442 ILE A CB 1 ATOM 3313 C CG1 . ILE A 1 440 ? 73.706 0.688 37.586 1.00 13.09 ? 442 ILE A CG1 1 ATOM 3314 C CG2 . ILE A 1 440 ? 74.574 0.011 39.832 1.00 12.51 ? 442 ILE A CG2 1 ATOM 3315 C CD1 . ILE A 1 440 ? 74.950 1.203 36.897 1.00 14.84 ? 442 ILE A CD1 1 ATOM 3316 N N . GLY A 1 441 ? 72.410 2.081 41.694 1.00 14.18 ? 443 GLY A N 1 ATOM 3317 C CA . GLY A 1 441 ? 72.227 2.294 43.126 1.00 15.87 ? 443 GLY A CA 1 ATOM 3318 C C . GLY A 1 441 ? 70.835 2.789 43.479 1.00 16.38 ? 443 GLY A C 1 ATOM 3319 O O . GLY A 1 441 ? 70.523 2.999 44.653 1.00 16.25 ? 443 GLY A O 1 ATOM 3320 N N . GLY A 1 442 ? 70.003 2.991 42.461 1.00 15.30 ? 444 GLY A N 1 ATOM 3321 C CA . GLY A 1 442 ? 68.597 3.328 42.664 1.00 14.36 ? 444 GLY A CA 1 ATOM 3322 C C . GLY A 1 442 ? 67.695 2.106 42.682 1.00 13.39 ? 444 GLY A C 1 ATOM 3323 O O . GLY A 1 442 ? 67.767 1.288 43.602 1.00 14.48 ? 444 GLY A O 1 ATOM 3324 N N . ARG A 1 443 ? 66.869 1.959 41.647 1.00 12.66 ? 445 ARG A N 1 ATOM 3325 C CA . ARG A 1 443 ? 65.871 0.888 41.605 1.00 11.82 ? 445 ARG A CA 1 ATOM 3326 C C . ARG A 1 443 ? 66.473 -0.498 41.799 1.00 12.01 ? 445 ARG A C 1 ATOM 3327 O O . ARG A 1 443 ? 65.913 -1.327 42.514 1.00 12.57 ? 445 ARG A O 1 ATOM 3328 C CB . ARG A 1 443 ? 65.071 0.925 40.299 1.00 12.15 ? 445 ARG A CB 1 ATOM 3329 C CG . ARG A 1 443 ? 64.131 -0.261 40.114 1.00 11.72 ? 445 ARG A CG 1 ATOM 3330 C CD . ARG A 1 443 ? 63.065 -0.302 41.197 1.00 12.13 ? 445 ARG A CD 1 ATOM 3331 N NE . ARG A 1 443 ? 62.247 -1.513 41.132 1.00 12.18 ? 445 ARG A NE 1 ATOM 3332 C CZ . ARG A 1 443 ? 62.472 -2.609 41.852 1.00 11.87 ? 445 ARG A CZ 1 ATOM 3333 N NH1 . ARG A 1 443 ? 63.503 -2.656 42.681 1.00 12.18 ? 445 ARG A NH1 1 ATOM 3334 N NH2 . ARG A 1 443 ? 61.667 -3.658 41.740 1.00 10.93 ? 445 ARG A NH2 1 ATOM 3335 N N . LEU A 1 444 ? 67.592 -0.765 41.134 1.00 12.25 ? 446 LEU A N 1 ATOM 3336 C CA . LEU A 1 444 ? 68.135 -2.121 41.098 1.00 12.69 ? 446 LEU A CA 1 ATOM 3337 C C . LEU A 1 444 ? 68.703 -2.557 42.448 1.00 13.23 ? 446 LEU A C 1 ATOM 3338 O O . LEU A 1 444 ? 68.816 -3.750 42.722 1.00 14.06 ? 446 LEU A O 1 ATOM 3339 C CB . LEU A 1 444 ? 69.189 -2.260 39.997 1.00 12.83 ? 446 LEU A CB 1 ATOM 3340 C CG . LEU A 1 444 ? 68.666 -1.980 38.583 1.00 13.00 ? 446 LEU A CG 1 ATOM 3341 C CD1 . LEU A 1 444 ? 69.756 -2.192 37.545 1.00 13.51 ? 446 LEU A CD1 1 ATOM 3342 C CD2 . LEU A 1 444 ? 67.458 -2.853 38.284 1.00 12.55 ? 446 LEU A CD2 1 ATOM 3343 N N . SER A 1 445 ? 69.019 -1.588 43.301 1.00 13.39 ? 447 SER A N 1 ATOM 3344 C CA . SER A 1 445 ? 69.508 -1.881 44.646 1.00 15.03 ? 447 SER A CA 1 ATOM 3345 C C . SER A 1 445 ? 68.397 -1.817 45.691 1.00 16.30 ? 447 SER A C 1 ATOM 3346 O O . SER A 1 445 ? 68.635 -2.067 46.875 1.00 17.53 ? 447 SER A O 1 ATOM 3347 C CB . SER A 1 445 ? 70.630 -0.912 45.029 1.00 15.06 ? 447 SER A CB 1 ATOM 3348 O OG . SER A 1 445 ? 71.770 -1.097 44.209 1.00 15.48 ? 447 SER A OG 1 ATOM 3349 N N . ALA A 1 446 ? 67.189 -1.472 45.257 1.00 17.64 ? 448 ALA A N 1 ATOM 3350 C CA . ALA A 1 446 ? 66.086 -1.221 46.184 1.00 20.35 ? 448 ALA A CA 1 ATOM 3351 C C . ALA A 1 446 ? 65.378 -2.507 46.610 1.00 24.21 ? 448 ALA A C 1 ATOM 3352 O O . ALA A 1 446 ? 64.964 -2.640 47.762 1.00 28.57 ? 448 ALA A O 1 ATOM 3353 C CB . ALA A 1 446 ? 65.091 -0.241 45.581 1.00 18.32 ? 448 ALA A CB 1 ATOM 3354 O OXT . ALA A 1 446 ? 65.201 -3.440 45.823 1.00 24.05 ? 448 ALA A OXT 1 ATOM 3355 N N . LEU B 1 2 ? 131.789 -27.589 35.165 1.00 27.18 ? 4 LEU B N 1 ATOM 3356 C CA . LEU B 1 2 ? 130.300 -27.508 35.067 1.00 25.44 ? 4 LEU B CA 1 ATOM 3357 C C . LEU B 1 2 ? 129.860 -26.846 33.763 1.00 24.00 ? 4 LEU B C 1 ATOM 3358 O O . LEU B 1 2 ? 130.162 -25.678 33.513 1.00 23.29 ? 4 LEU B O 1 ATOM 3359 C CB . LEU B 1 2 ? 129.718 -26.757 36.269 1.00 26.10 ? 4 LEU B CB 1 ATOM 3360 C CG . LEU B 1 2 ? 128.206 -26.894 36.475 1.00 24.98 ? 4 LEU B CG 1 ATOM 3361 C CD1 . LEU B 1 2 ? 127.841 -28.318 36.870 1.00 24.23 ? 4 LEU B CD1 1 ATOM 3362 C CD2 . LEU B 1 2 ? 127.702 -25.906 37.515 1.00 24.55 ? 4 LEU B CD2 1 ATOM 3363 N N . ASN B 1 3 ? 129.153 -27.604 32.932 1.00 20.95 ? 5 ASN B N 1 ATOM 3364 C CA . ASN B 1 3 ? 128.712 -27.118 31.630 1.00 20.34 ? 5 ASN B CA 1 ATOM 3365 C C . ASN B 1 3 ? 127.370 -26.400 31.726 1.00 20.07 ? 5 ASN B C 1 ATOM 3366 O O . ASN B 1 3 ? 126.317 -27.004 31.521 1.00 20.46 ? 5 ASN B O 1 ATOM 3367 C CB . ASN B 1 3 ? 128.614 -28.283 30.645 1.00 20.13 ? 5 ASN B CB 1 ATOM 3368 C CG . ASN B 1 3 ? 128.215 -27.841 29.251 1.00 20.02 ? 5 ASN B CG 1 ATOM 3369 O OD1 . ASN B 1 3 ? 128.036 -26.651 28.987 1.00 20.56 ? 5 ASN B OD1 1 ATOM 3370 N ND2 . ASN B 1 3 ? 128.065 -28.803 28.351 1.00 22.41 ? 5 ASN B ND2 1 ATOM 3371 N N . THR B 1 4 ? 127.411 -25.112 32.048 1.00 19.46 ? 6 THR B N 1 ATOM 3372 C CA . THR B 1 4 ? 126.192 -24.361 32.330 1.00 18.57 ? 6 THR B CA 1 ATOM 3373 C C . THR B 1 4 ? 125.403 -24.062 31.059 1.00 17.90 ? 6 THR B C 1 ATOM 3374 O O . THR B 1 4 ? 124.248 -23.635 31.123 1.00 17.75 ? 6 THR B O 1 ATOM 3375 C CB . THR B 1 4 ? 126.496 -23.041 33.067 1.00 18.72 ? 6 THR B CB 1 ATOM 3376 O OG1 . THR B 1 4 ? 127.394 -22.253 32.280 1.00 18.71 ? 6 THR B OG1 1 ATOM 3377 C CG2 . THR B 1 4 ? 127.127 -23.318 34.428 1.00 18.76 ? 6 THR B CG2 1 ATOM 3378 N N . ASP B 1 5 ? 126.033 -24.266 29.907 1.00 17.79 ? 7 ASP B N 1 ATOM 3379 C CA . ASP B 1 5 ? 125.341 -24.151 28.628 1.00 17.52 ? 7 ASP B CA 1 ATOM 3380 C C . ASP B 1 5 ? 124.261 -25.218 28.494 1.00 16.32 ? 7 ASP B C 1 ATOM 3381 O O . ASP B 1 5 ? 123.344 -25.081 27.685 1.00 16.55 ? 7 ASP B O 1 ATOM 3382 C CB . ASP B 1 5 ? 126.322 -24.297 27.461 1.00 19.42 ? 7 ASP B CB 1 ATOM 3383 C CG . ASP B 1 5 ? 127.264 -23.115 27.331 1.00 22.43 ? 7 ASP B CG 1 ATOM 3384 O OD1 . ASP B 1 5 ? 127.159 -22.163 28.135 1.00 21.90 ? 7 ASP B OD1 1 ATOM 3385 O OD2 . ASP B 1 5 ? 128.119 -23.146 26.422 1.00 24.07 ? 7 ASP B OD2 1 ATOM 3386 N N . ASP B 1 6 ? 124.422 -26.319 29.221 1.00 14.33 ? 8 ASP B N 1 ATOM 3387 C CA . ASP B 1 6 ? 123.553 -27.478 29.031 1.00 13.74 ? 8 ASP B CA 1 ATOM 3388 C C . ASP B 1 6 ? 122.572 -27.657 30.186 1.00 12.49 ? 8 ASP B C 1 ATOM 3389 O O . ASP B 1 6 ? 121.790 -28.608 30.205 1.00 12.01 ? 8 ASP B O 1 ATOM 3390 C CB . ASP B 1 6 ? 124.380 -28.752 28.826 1.00 14.07 ? 8 ASP B CB 1 ATOM 3391 C CG . ASP B 1 6 ? 123.597 -29.847 28.125 1.00 15.30 ? 8 ASP B CG 1 ATOM 3392 O OD1 . ASP B 1 6 ? 122.696 -29.519 27.320 1.00 14.19 ? 8 ASP B OD1 1 ATOM 3393 O OD2 . ASP B 1 6 ? 123.872 -31.037 28.391 1.00 15.66 ? 8 ASP B OD2 1 ATOM 3394 N N . ILE B 1 7 ? 122.612 -26.732 31.142 1.00 10.89 ? 9 ILE B N 1 ATOM 3395 C CA . ILE B 1 7 ? 121.743 -26.795 32.314 1.00 10.11 ? 9 ILE B CA 1 ATOM 3396 C C . ILE B 1 7 ? 120.606 -25.790 32.174 1.00 9.61 ? 9 ILE B C 1 ATOM 3397 O O . ILE B 1 7 ? 120.825 -24.643 31.780 1.00 9.46 ? 9 ILE B O 1 ATOM 3398 C CB . ILE B 1 7 ? 122.523 -26.506 33.612 1.00 9.87 ? 9 ILE B CB 1 ATOM 3399 C CG1 . ILE B 1 7 ? 123.638 -27.538 33.797 1.00 10.15 ? 9 ILE B CG1 1 ATOM 3400 C CG2 . ILE B 1 7 ? 121.594 -26.518 34.817 1.00 9.17 ? 9 ILE B CG2 1 ATOM 3401 C CD1 . ILE B 1 7 ? 124.558 -27.243 34.958 1.00 9.96 ? 9 ILE B CD1 1 ATOM 3402 N N . GLN B 1 8 ? 119.385 -26.228 32.464 1.00 8.89 ? 10 GLN B N 1 ATOM 3403 C CA . GLN B 1 8 ? 118.230 -25.348 32.340 1.00 8.97 ? 10 GLN B CA 1 ATOM 3404 C C . GLN B 1 8 ? 118.276 -24.202 33.341 1.00 9.13 ? 10 GLN B C 1 ATOM 3405 O O . GLN B 1 8 ? 118.578 -24.402 34.518 1.00 9.20 ? 10 GLN B O 1 ATOM 3406 C CB . GLN B 1 8 ? 116.927 -26.134 32.481 1.00 8.93 ? 10 GLN B CB 1 ATOM 3407 C CG . GLN B 1 8 ? 116.700 -27.132 31.359 1.00 8.74 ? 10 GLN B CG 1 ATOM 3408 C CD . GLN B 1 8 ? 115.253 -27.566 31.252 1.00 8.94 ? 10 GLN B CD 1 ATOM 3409 O OE1 . GLN B 1 8 ? 114.346 -26.733 31.224 1.00 8.53 ? 10 GLN B OE1 1 ATOM 3410 N NE2 . GLN B 1 8 ? 115.028 -28.875 31.196 1.00 9.25 ? 10 GLN B NE2 1 ATOM 3411 N N . GLY B 1 9 ? 117.924 -23.009 32.876 1.00 9.12 ? 11 GLY B N 1 ATOM 3412 C CA . GLY B 1 9 ? 118.225 -21.777 33.601 1.00 9.28 ? 11 GLY B CA 1 ATOM 3413 C C . GLY B 1 9 ? 117.596 -21.666 34.978 1.00 9.46 ? 11 GLY B C 1 ATOM 3414 O O . GLY B 1 9 ? 118.202 -21.111 35.893 1.00 9.74 ? 11 GLY B O 1 ATOM 3415 N N . ASP B 1 10 ? 116.374 -22.171 35.129 1.00 9.63 ? 12 ASP B N 1 ATOM 3416 C CA . ASP B 1 10 ? 115.633 -21.993 36.382 1.00 10.00 ? 12 ASP B CA 1 ATOM 3417 C C . ASP B 1 10 ? 116.323 -22.701 37.545 1.00 10.06 ? 12 ASP B C 1 ATOM 3418 O O . ASP B 1 10 ? 116.149 -22.327 38.704 1.00 11.04 ? 12 ASP B O 1 ATOM 3419 C CB . ASP B 1 10 ? 114.186 -22.485 36.242 1.00 10.18 ? 12 ASP B CB 1 ATOM 3420 C CG . ASP B 1 10 ? 113.291 -22.022 37.388 1.00 11.24 ? 12 ASP B CG 1 ATOM 3421 O OD1 . ASP B 1 10 ? 113.407 -20.849 37.805 1.00 11.52 ? 12 ASP B OD1 1 ATOM 3422 O OD2 . ASP B 1 10 ? 112.432 -22.816 37.840 1.00 11.15 ? 12 ASP B OD2 1 ATOM 3423 N N . ILE B 1 11 ? 117.078 -23.748 37.234 1.00 10.19 ? 13 ILE B N 1 ATOM 3424 C CA . ILE B 1 11 ? 117.695 -24.574 38.266 1.00 10.45 ? 13 ILE B CA 1 ATOM 3425 C C . ILE B 1 11 ? 118.707 -23.805 39.117 1.00 11.32 ? 13 ILE B C 1 ATOM 3426 O O . ILE B 1 11 ? 118.658 -23.852 40.351 1.00 11.82 ? 13 ILE B O 1 ATOM 3427 C CB . ILE B 1 11 ? 118.360 -25.823 37.661 1.00 10.13 ? 13 ILE B CB 1 ATOM 3428 C CG1 . ILE B 1 11 ? 117.319 -26.670 36.926 1.00 9.69 ? 13 ILE B CG1 1 ATOM 3429 C CG2 . ILE B 1 11 ? 119.048 -26.641 38.742 1.00 10.07 ? 13 ILE B CG2 1 ATOM 3430 C CD1 . ILE B 1 11 ? 117.912 -27.679 35.971 1.00 9.30 ? 13 ILE B CD1 1 ATOM 3431 N N . LEU B 1 12 ? 119.599 -23.071 38.459 1.00 11.76 ? 14 LEU B N 1 ATOM 3432 C CA . LEU B 1 12 ? 120.723 -22.441 39.149 1.00 13.05 ? 14 LEU B CA 1 ATOM 3433 C C . LEU B 1 12 ? 120.603 -20.923 39.284 1.00 14.59 ? 14 LEU B C 1 ATOM 3434 O O . LEU B 1 12 ? 121.230 -20.329 40.162 1.00 14.49 ? 14 LEU B O 1 ATOM 3435 C CB . LEU B 1 12 ? 122.048 -22.807 38.475 1.00 13.33 ? 14 LEU B CB 1 ATOM 3436 C CG . LEU B 1 12 ? 122.481 -24.270 38.592 1.00 13.42 ? 14 LEU B CG 1 ATOM 3437 C CD1 . LEU B 1 12 ? 123.881 -24.457 38.027 1.00 13.63 ? 14 LEU B CD1 1 ATOM 3438 C CD2 . LEU B 1 12 ? 122.407 -24.739 40.039 1.00 12.76 ? 14 LEU B CD2 1 ATOM 3439 N N . VAL B 1 13 ? 119.823 -20.289 38.413 1.00 14.83 ? 15 VAL B N 1 ATOM 3440 C CA . VAL B 1 13 ? 119.734 -18.829 38.429 1.00 15.91 ? 15 VAL B CA 1 ATOM 3441 C C . VAL B 1 13 ? 118.322 -18.283 38.637 1.00 16.26 ? 15 VAL B C 1 ATOM 3442 O O . VAL B 1 13 ? 118.157 -17.150 39.077 1.00 17.83 ? 15 VAL B O 1 ATOM 3443 C CB . VAL B 1 13 ? 120.359 -18.186 37.173 1.00 16.69 ? 15 VAL B CB 1 ATOM 3444 C CG1 . VAL B 1 13 ? 121.782 -18.681 36.966 1.00 17.56 ? 15 VAL B CG1 1 ATOM 3445 C CG2 . VAL B 1 13 ? 119.507 -18.457 35.946 1.00 17.71 ? 15 VAL B CG2 1 ATOM 3446 N N . GLY B 1 14 ? 117.309 -19.074 38.302 1.00 15.50 ? 16 GLY B N 1 ATOM 3447 C CA . GLY B 1 14 ? 115.932 -18.580 38.280 1.00 16.55 ? 16 GLY B CA 1 ATOM 3448 C C . GLY B 1 14 ? 115.593 -17.904 36.963 1.00 17.73 ? 16 GLY B C 1 ATOM 3449 O O . GLY B 1 14 ? 116.482 -17.588 36.176 1.00 18.63 ? 16 GLY B O 1 ATOM 3450 N N . MET B 1 15 ? 114.307 -17.678 36.719 1.00 18.31 ? 17 MET B N 1 ATOM 3451 C CA . MET B 1 15 ? 113.849 -17.203 35.414 1.00 20.38 ? 17 MET B CA 1 ATOM 3452 C C . MET B 1 15 ? 114.085 -15.705 35.195 1.00 22.77 ? 17 MET B C 1 ATOM 3453 O O . MET B 1 15 ? 114.197 -15.248 34.057 1.00 24.49 ? 17 MET B O 1 ATOM 3454 C CB . MET B 1 15 ? 112.372 -17.541 35.207 1.00 19.12 ? 17 MET B CB 1 ATOM 3455 C CG . MET B 1 15 ? 112.097 -19.021 34.991 1.00 18.81 ? 17 MET B CG 1 ATOM 3456 S SD . MET B 1 15 ? 113.190 -19.754 33.757 1.00 19.52 ? 17 MET B SD 1 ATOM 3457 C CE . MET B 1 15 ? 112.017 -20.668 32.759 1.00 17.33 ? 17 MET B CE 1 ATOM 3458 N N . HIS B 1 16 ? 114.110 -14.941 36.282 1.00 24.55 ? 18 HIS B N 1 ATOM 3459 C CA . HIS B 1 16 ? 114.429 -13.517 36.207 1.00 29.24 ? 18 HIS B CA 1 ATOM 3460 C C . HIS B 1 16 ? 113.376 -12.715 35.445 1.00 25.63 ? 18 HIS B C 1 ATOM 3461 O O . HIS B 1 16 ? 113.715 -11.791 34.706 1.00 27.86 ? 18 HIS B O 1 ATOM 3462 C CB . HIS B 1 16 ? 115.797 -13.308 35.550 1.00 31.99 ? 18 HIS B CB 1 ATOM 3463 C CG . HIS B 1 16 ? 116.946 -13.362 36.508 1.00 37.86 ? 18 HIS B CG 1 ATOM 3464 N ND1 . HIS B 1 16 ? 117.958 -14.291 36.404 1.00 42.38 ? 18 HIS B ND1 1 ATOM 3465 C CD2 . HIS B 1 16 ? 117.245 -12.598 37.586 1.00 39.37 ? 18 HIS B CD2 1 ATOM 3466 C CE1 . HIS B 1 16 ? 118.831 -14.098 37.377 1.00 41.69 ? 18 HIS B CE1 1 ATOM 3467 N NE2 . HIS B 1 16 ? 118.422 -13.077 38.108 1.00 40.91 ? 18 HIS B NE2 1 ATOM 3468 N N . LYS B 1 17 ? 112.105 -13.073 35.612 1.00 23.10 ? 19 LYS B N 1 ATOM 3469 C CA . LYS B 1 17 ? 111.026 -12.380 34.909 1.00 19.43 ? 19 LYS B CA 1 ATOM 3470 C C . LYS B 1 17 ? 109.863 -12.031 35.835 1.00 18.95 ? 19 LYS B C 1 ATOM 3471 O O . LYS B 1 17 ? 109.684 -12.649 36.884 1.00 17.01 ? 19 LYS B O 1 ATOM 3472 C CB . LYS B 1 17 ? 110.527 -13.215 33.726 1.00 19.48 ? 19 LYS B CB 1 ATOM 3473 C CG . LYS B 1 17 ? 111.604 -13.565 32.710 1.00 19.99 ? 19 LYS B CG 1 ATOM 3474 C CD . LYS B 1 17 ? 111.968 -12.364 31.851 1.00 20.85 ? 19 LYS B CD 1 ATOM 3475 C CE . LYS B 1 17 ? 112.788 -12.784 30.642 1.00 21.87 ? 19 LYS B CE 1 ATOM 3476 N NZ . LYS B 1 17 ? 112.965 -11.672 29.667 1.00 21.53 ? 19 LYS B NZ 1 ATOM 3477 N N . GLN B 1 18 ? 109.066 -11.046 35.428 1.00 17.37 ? 20 GLN B N 1 ATOM 3478 C CA . GLN B 1 18 ? 107.951 -10.570 36.237 1.00 17.53 ? 20 GLN B CA 1 ATOM 3479 C C . GLN B 1 18 ? 106.846 -11.614 36.341 1.00 15.16 ? 20 GLN B C 1 ATOM 3480 O O . GLN B 1 18 ? 106.227 -11.769 37.394 1.00 14.44 ? 20 GLN B O 1 ATOM 3481 C CB . GLN B 1 18 ? 107.381 -9.273 35.654 1.00 19.68 ? 20 GLN B CB 1 ATOM 3482 C CG . GLN B 1 18 ? 108.251 -8.051 35.899 1.00 22.73 ? 20 GLN B CG 1 ATOM 3483 C CD . GLN B 1 18 ? 108.280 -7.648 37.360 1.00 24.65 ? 20 GLN B CD 1 ATOM 3484 O OE1 . GLN B 1 18 ? 107.240 -7.574 38.018 1.00 29.48 ? 20 GLN B OE1 1 ATOM 3485 N NE2 . GLN B 1 18 ? 109.475 -7.396 37.879 1.00 26.62 ? 20 GLN B NE2 1 ATOM 3486 N N . LYS B 1 19 ? 106.577 -12.300 35.235 1.00 12.71 ? 21 LYS B N 1 ATOM 3487 C CA . LYS B 1 19 ? 105.488 -13.269 35.186 1.00 12.03 ? 21 LYS B CA 1 ATOM 3488 C C . LYS B 1 19 ? 106.024 -14.664 34.889 1.00 11.00 ? 21 LYS B C 1 ATOM 3489 O O . LYS B 1 19 ? 107.004 -14.822 34.157 1.00 10.71 ? 21 LYS B O 1 ATOM 3490 C CB . LYS B 1 19 ? 104.454 -12.877 34.124 1.00 12.29 ? 21 LYS B CB 1 ATOM 3491 C CG . LYS B 1 19 ? 104.009 -11.423 34.175 1.00 13.30 ? 21 LYS B CG 1 ATOM 3492 C CD . LYS B 1 19 ? 103.209 -11.122 35.433 1.00 14.87 ? 21 LYS B CD 1 ATOM 3493 C CE . LYS B 1 19 ? 102.677 -9.697 35.416 1.00 18.12 ? 21 LYS B CE 1 ATOM 3494 N NZ . LYS B 1 19 ? 101.904 -9.391 36.651 1.00 18.06 ? 21 LYS B NZ 1 ATOM 3495 N N . GLN B 1 20 ? 105.384 -15.673 35.468 1.00 11.06 ? 22 GLN B N 1 ATOM 3496 C CA . GLN B 1 20 ? 105.631 -17.058 35.078 1.00 10.75 ? 22 GLN B CA 1 ATOM 3497 C C . GLN B 1 20 ? 104.316 -17.804 34.933 1.00 10.24 ? 22 GLN B C 1 ATOM 3498 O O . GLN B 1 20 ? 103.345 -17.513 35.631 1.00 10.81 ? 22 GLN B O 1 ATOM 3499 C CB . GLN B 1 20 ? 106.521 -17.767 36.106 1.00 11.23 ? 22 GLN B CB 1 ATOM 3500 C CG . GLN B 1 20 ? 107.937 -17.221 36.186 1.00 12.27 ? 22 GLN B CG 1 ATOM 3501 C CD . GLN B 1 20 ? 108.874 -18.110 36.992 1.00 12.45 ? 22 GLN B CD 1 ATOM 3502 O OE1 . GLN B 1 20 ? 109.943 -17.674 37.412 1.00 15.20 ? 22 GLN B OE1 1 ATOM 3503 N NE2 . GLN B 1 20 ? 108.481 -19.364 37.201 1.00 12.68 ? 22 GLN B NE2 1 ATOM 3504 N N . LEU B 1 21 ? 104.294 -18.769 34.023 1.00 9.97 ? 23 LEU B N 1 ATOM 3505 C CA . LEU B 1 21 ? 103.205 -19.727 33.943 1.00 9.67 ? 23 LEU B CA 1 ATOM 3506 C C . LEU B 1 21 ? 103.758 -21.131 34.150 1.00 9.42 ? 23 LEU B C 1 ATOM 3507 O O . LEU B 1 21 ? 104.795 -21.482 33.589 1.00 9.71 ? 23 LEU B O 1 ATOM 3508 C CB . LEU B 1 21 ? 102.522 -19.637 32.578 1.00 10.07 ? 23 LEU B CB 1 ATOM 3509 C CG . LEU B 1 21 ? 101.367 -20.614 32.343 1.00 10.52 ? 23 LEU B CG 1 ATOM 3510 C CD1 . LEU B 1 21 ? 100.166 -20.211 33.177 1.00 10.82 ? 23 LEU B CD1 1 ATOM 3511 C CD2 . LEU B 1 21 ? 101.004 -20.669 30.865 1.00 11.30 ? 23 LEU B CD2 1 ATOM 3512 N N . PHE B 1 22 ? 103.082 -21.917 34.982 1.00 9.24 ? 24 PHE B N 1 ATOM 3513 C CA . PHE B 1 22 ? 103.348 -23.348 35.079 1.00 9.02 ? 24 PHE B CA 1 ATOM 3514 C C . PHE B 1 22 ? 102.266 -24.110 34.323 1.00 8.84 ? 24 PHE B C 1 ATOM 3515 O O . PHE B 1 22 ? 101.092 -24.067 34.691 1.00 9.14 ? 24 PHE B O 1 ATOM 3516 C CB . PHE B 1 22 ? 103.383 -23.787 36.549 1.00 9.03 ? 24 PHE B CB 1 ATOM 3517 C CG . PHE B 1 22 ? 104.478 -23.137 37.349 1.00 9.04 ? 24 PHE B CG 1 ATOM 3518 C CD1 . PHE B 1 22 ? 104.265 -21.922 37.984 1.00 8.98 ? 24 PHE B CD1 1 ATOM 3519 C CD2 . PHE B 1 22 ? 105.724 -23.735 37.456 1.00 9.01 ? 24 PHE B CD2 1 ATOM 3520 C CE1 . PHE B 1 22 ? 105.270 -21.325 38.723 1.00 9.23 ? 24 PHE B CE1 1 ATOM 3521 C CE2 . PHE B 1 22 ? 106.739 -23.136 38.182 1.00 9.08 ? 24 PHE B CE2 1 ATOM 3522 C CZ . PHE B 1 22 ? 106.510 -21.930 38.818 1.00 9.35 ? 24 PHE B CZ 1 ATOM 3523 N N . TYR B 1 23 ? 102.664 -24.772 33.243 1.00 8.89 ? 25 TYR B N 1 ATOM 3524 C CA . TYR B 1 23 ? 101.723 -25.414 32.331 1.00 8.61 ? 25 TYR B CA 1 ATOM 3525 C C . TYR B 1 23 ? 101.890 -26.923 32.452 1.00 8.39 ? 25 TYR B C 1 ATOM 3526 O O . TYR B 1 23 ? 102.890 -27.474 32.002 1.00 7.67 ? 25 TYR B O 1 ATOM 3527 C CB . TYR B 1 23 ? 102.021 -24.966 30.893 1.00 8.85 ? 25 TYR B CB 1 ATOM 3528 C CG . TYR B 1 23 ? 101.060 -25.472 29.834 1.00 9.64 ? 25 TYR B CG 1 ATOM 3529 C CD1 . TYR B 1 23 ? 101.262 -26.697 29.208 1.00 10.13 ? 25 TYR B CD1 1 ATOM 3530 C CD2 . TYR B 1 23 ? 100.010 -24.678 29.387 1.00 10.38 ? 25 TYR B CD2 1 ATOM 3531 C CE1 . TYR B 1 23 ? 100.414 -27.139 28.205 1.00 10.19 ? 25 TYR B CE1 1 ATOM 3532 C CE2 . TYR B 1 23 ? 99.157 -25.112 28.385 1.00 10.41 ? 25 TYR B CE2 1 ATOM 3533 C CZ . TYR B 1 23 ? 99.363 -26.341 27.797 1.00 11.17 ? 25 TYR B CZ 1 ATOM 3534 O OH . TYR B 1 23 ? 98.521 -26.770 26.792 1.00 12.33 ? 25 TYR B OH 1 ATOM 3535 N N . PHE B 1 24 ? 100.935 -27.581 33.103 1.00 8.39 ? 26 PHE B N 1 ATOM 3536 C CA . PHE B 1 24 ? 101.060 -29.009 33.388 1.00 8.58 ? 26 PHE B CA 1 ATOM 3537 C C . PHE B 1 24 ? 100.321 -29.822 32.333 1.00 8.62 ? 26 PHE B C 1 ATOM 3538 O O . PHE B 1 24 ? 99.136 -29.599 32.087 1.00 8.79 ? 26 PHE B O 1 ATOM 3539 C CB . PHE B 1 24 ? 100.522 -29.335 34.783 1.00 8.62 ? 26 PHE B CB 1 ATOM 3540 C CG . PHE B 1 24 ? 101.233 -28.611 35.891 1.00 8.65 ? 26 PHE B CG 1 ATOM 3541 C CD1 . PHE B 1 24 ? 102.404 -29.122 36.432 1.00 8.54 ? 26 PHE B CD1 1 ATOM 3542 C CD2 . PHE B 1 24 ? 100.747 -27.405 36.372 1.00 8.58 ? 26 PHE B CD2 1 ATOM 3543 C CE1 . PHE B 1 24 ? 103.074 -28.446 37.439 1.00 8.26 ? 26 PHE B CE1 1 ATOM 3544 C CE2 . PHE B 1 24 ? 101.408 -26.728 37.383 1.00 8.51 ? 26 PHE B CE2 1 ATOM 3545 C CZ . PHE B 1 24 ? 102.575 -27.248 37.913 1.00 8.32 ? 26 PHE B CZ 1 ATOM 3546 N N . PHE B 1 25 ? 101.027 -30.756 31.703 1.00 8.88 ? 27 PHE B N 1 ATOM 3547 C CA . PHE B 1 25 ? 100.516 -31.408 30.499 1.00 9.31 ? 27 PHE B CA 1 ATOM 3548 C C . PHE B 1 25 ? 100.560 -32.932 30.572 1.00 9.38 ? 27 PHE B C 1 ATOM 3549 O O . PHE B 1 25 ? 101.302 -33.507 31.371 1.00 8.66 ? 27 PHE B O 1 ATOM 3550 C CB . PHE B 1 25 ? 101.254 -30.911 29.251 1.00 9.36 ? 27 PHE B CB 1 ATOM 3551 C CG . PHE B 1 25 ? 102.718 -31.265 29.222 1.00 9.34 ? 27 PHE B CG 1 ATOM 3552 C CD1 . PHE B 1 25 ? 103.146 -32.453 28.649 1.00 9.54 ? 27 PHE B CD1 1 ATOM 3553 C CD2 . PHE B 1 25 ? 103.668 -30.395 29.736 1.00 9.40 ? 27 PHE B CD2 1 ATOM 3554 C CE1 . PHE B 1 25 ? 104.490 -32.775 28.601 1.00 9.34 ? 27 PHE B CE1 1 ATOM 3555 C CE2 . PHE B 1 25 ? 105.016 -30.707 29.688 1.00 9.43 ? 27 PHE B CE2 1 ATOM 3556 C CZ . PHE B 1 25 ? 105.427 -31.906 29.128 1.00 9.51 ? 27 PHE B CZ 1 ATOM 3557 N N . ALA B 1 26 ? 99.717 -33.572 29.766 1.00 9.89 ? 28 ALA B N 1 ATOM 3558 C CA . ALA B 1 26 ? 99.855 -34.990 29.458 1.00 10.80 ? 28 ALA B CA 1 ATOM 3559 C C . ALA B 1 26 ? 100.310 -35.166 28.014 1.00 11.71 ? 28 ALA B C 1 ATOM 3560 O O . ALA B 1 26 ? 100.034 -34.324 27.159 1.00 12.00 ? 28 ALA B O 1 ATOM 3561 C CB . ALA B 1 26 ? 98.532 -35.714 29.680 1.00 11.09 ? 28 ALA B CB 1 ATOM 3562 N N . ILE B 1 27 ? 101.032 -36.252 27.760 1.00 12.07 ? 29 ILE B N 1 ATOM 3563 C CA . ILE B 1 27 ? 101.438 -36.622 26.411 1.00 13.10 ? 29 ILE B CA 1 ATOM 3564 C C . ILE B 1 27 ? 100.475 -37.674 25.862 1.00 15.01 ? 29 ILE B C 1 ATOM 3565 O O . ILE B 1 27 ? 100.229 -38.691 26.511 1.00 15.14 ? 29 ILE B O 1 ATOM 3566 C CB . ILE B 1 27 ? 102.870 -37.199 26.409 1.00 13.17 ? 29 ILE B CB 1 ATOM 3567 C CG1 . ILE B 1 27 ? 103.873 -36.129 26.851 1.00 13.07 ? 29 ILE B CG1 1 ATOM 3568 C CG2 . ILE B 1 27 ? 103.228 -37.749 25.034 1.00 12.60 ? 29 ILE B CG2 1 ATOM 3569 C CD1 . ILE B 1 27 ? 105.171 -36.685 27.396 1.00 13.30 ? 29 ILE B CD1 1 ATOM 3570 N N . ASN B 1 28 ? 99.926 -37.426 24.675 1.00 16.42 ? 30 ASN B N 1 ATOM 3571 C CA . ASN B 1 28 ? 98.930 -38.328 24.090 1.00 19.08 ? 30 ASN B CA 1 ATOM 3572 C C . ASN B 1 28 ? 99.507 -39.246 23.020 1.00 21.70 ? 30 ASN B C 1 ATOM 3573 O O . ASN B 1 28 ? 99.072 -40.388 22.867 1.00 26.47 ? 30 ASN B O 1 ATOM 3574 C CB . ASN B 1 28 ? 97.762 -37.535 23.503 1.00 18.28 ? 30 ASN B CB 1 ATOM 3575 C CG . ASN B 1 28 ? 97.080 -36.664 24.533 1.00 19.00 ? 30 ASN B CG 1 ATOM 3576 O OD1 . ASN B 1 28 ? 96.849 -37.092 25.661 1.00 21.83 ? 30 ASN B OD1 1 ATOM 3577 N ND2 . ASN B 1 28 ? 96.802 -35.418 24.167 1.00 18.38 ? 30 ASN B ND2 1 ATOM 3578 N N . ASP B 1 29 ? 100.460 -38.725 22.259 1.00 19.79 ? 31 ASP B N 1 ATOM 3579 C CA . ASP B 1 29 ? 100.968 -39.406 21.078 1.00 19.43 ? 31 ASP B CA 1 ATOM 3580 C C . ASP B 1 29 ? 102.477 -39.213 21.009 1.00 18.62 ? 31 ASP B C 1 ATOM 3581 O O . ASP B 1 29 ? 102.954 -38.204 20.490 1.00 17.07 ? 31 ASP B O 1 ATOM 3582 C CB . ASP B 1 29 ? 100.293 -38.838 19.828 1.00 20.51 ? 31 ASP B CB 1 ATOM 3583 C CG . ASP B 1 29 ? 100.943 -39.302 18.542 1.00 22.18 ? 31 ASP B CG 1 ATOM 3584 O OD1 . ASP B 1 29 ? 101.930 -40.066 18.595 1.00 22.18 ? 31 ASP B OD1 1 ATOM 3585 O OD2 . ASP B 1 29 ? 100.467 -38.883 17.466 1.00 27.63 ? 31 ASP B OD2 1 ATOM 3586 N N . PRO B 1 30 ? 103.230 -40.149 21.609 1.00 18.08 ? 32 PRO B N 1 ATOM 3587 C CA . PRO B 1 30 ? 104.661 -40.003 21.849 1.00 17.48 ? 32 PRO B CA 1 ATOM 3588 C C . PRO B 1 30 ? 105.450 -39.640 20.595 1.00 15.99 ? 32 PRO B C 1 ATOM 3589 O O . PRO B 1 30 ? 106.296 -38.745 20.637 1.00 14.80 ? 32 PRO B O 1 ATOM 3590 C CB . PRO B 1 30 ? 105.066 -41.387 22.352 1.00 17.39 ? 32 PRO B CB 1 ATOM 3591 C CG . PRO B 1 30 ? 103.849 -41.883 23.052 1.00 17.56 ? 32 PRO B CG 1 ATOM 3592 C CD . PRO B 1 30 ? 102.671 -41.325 22.300 1.00 18.82 ? 32 PRO B CD 1 ATOM 3593 N N . ALA B 1 31 ? 105.184 -40.330 19.490 1.00 15.48 ? 33 ALA B N 1 ATOM 3594 C CA . ALA B 1 31 ? 105.932 -40.096 18.259 1.00 15.30 ? 33 ALA B CA 1 ATOM 3595 C C . ALA B 1 31 ? 105.776 -38.652 17.790 1.00 14.35 ? 33 ALA B C 1 ATOM 3596 O O . ALA B 1 31 ? 106.755 -37.987 17.451 1.00 13.56 ? 33 ALA B O 1 ATOM 3597 C CB . ALA B 1 31 ? 105.494 -41.067 17.170 1.00 15.66 ? 33 ALA B CB 1 ATOM 3598 N N . THR B 1 32 ? 104.539 -38.167 17.784 1.00 14.35 ? 34 THR B N 1 ATOM 3599 C CA . THR B 1 32 ? 104.264 -36.782 17.412 1.00 13.86 ? 34 THR B CA 1 ATOM 3600 C C . THR B 1 32 ? 104.870 -35.813 18.425 1.00 12.93 ? 34 THR B C 1 ATOM 3601 O O . THR B 1 32 ? 105.544 -34.858 18.049 1.00 11.69 ? 34 THR B O 1 ATOM 3602 C CB . THR B 1 32 ? 102.750 -36.521 17.288 1.00 15.79 ? 34 THR B CB 1 ATOM 3603 O OG1 . THR B 1 32 ? 102.187 -37.423 16.327 1.00 15.32 ? 34 THR B OG1 1 ATOM 3604 C CG2 . THR B 1 32 ? 102.483 -35.084 16.853 1.00 14.24 ? 34 THR B CG2 1 ATOM 3605 N N . PHE B 1 33 ? 104.640 -36.075 19.710 1.00 12.64 ? 35 PHE B N 1 ATOM 3606 C CA . PHE B 1 33 ? 105.221 -35.258 20.776 1.00 11.78 ? 35 PHE B CA 1 ATOM 3607 C C . PHE B 1 33 ? 106.734 -35.120 20.611 1.00 12.16 ? 35 PHE B C 1 ATOM 3608 O O . PHE B 1 33 ? 107.281 -34.023 20.699 1.00 10.92 ? 35 PHE B O 1 ATOM 3609 C CB . PHE B 1 33 ? 104.899 -35.855 22.150 1.00 11.93 ? 35 PHE B CB 1 ATOM 3610 C CG . PHE B 1 33 ? 105.309 -34.980 23.303 1.00 12.45 ? 35 PHE B CG 1 ATOM 3611 C CD1 . PHE B 1 33 ? 104.448 -34.010 23.794 1.00 12.76 ? 35 PHE B CD1 1 ATOM 3612 C CD2 . PHE B 1 33 ? 106.559 -35.116 23.885 1.00 13.21 ? 35 PHE B CD2 1 ATOM 3613 C CE1 . PHE B 1 33 ? 104.828 -33.194 24.845 1.00 12.93 ? 35 PHE B CE1 1 ATOM 3614 C CE2 . PHE B 1 33 ? 106.944 -34.303 24.937 1.00 13.24 ? 35 PHE B CE2 1 ATOM 3615 C CZ . PHE B 1 33 ? 106.080 -33.334 25.409 1.00 13.19 ? 35 PHE B CZ 1 ATOM 3616 N N . LYS B 1 34 ? 107.406 -36.242 20.373 1.00 12.08 ? 36 LYS B N 1 ATOM 3617 C CA . LYS B 1 34 ? 108.860 -36.257 20.284 1.00 12.10 ? 36 LYS B CA 1 ATOM 3618 C C . LYS B 1 34 ? 109.386 -35.372 19.162 1.00 11.66 ? 36 LYS B C 1 ATOM 3619 O O . LYS B 1 34 ? 110.393 -34.692 19.328 1.00 10.93 ? 36 LYS B O 1 ATOM 3620 C CB . LYS B 1 34 ? 109.376 -37.684 20.103 1.00 12.47 ? 36 LYS B CB 1 ATOM 3621 C CG . LYS B 1 34 ? 109.337 -38.524 21.368 1.00 13.76 ? 36 LYS B CG 1 ATOM 3622 C CD . LYS B 1 34 ? 109.577 -39.990 21.035 1.00 15.52 ? 36 LYS B CD 1 ATOM 3623 C CE . LYS B 1 34 ? 109.741 -40.830 22.290 1.00 16.39 ? 36 LYS B CE 1 ATOM 3624 N NZ . LYS B 1 34 ? 111.052 -40.560 22.946 1.00 16.97 ? 36 LYS B NZ 1 ATOM 3625 N N . THR B 1 35 ? 108.738 -35.422 18.002 1.00 12.33 ? 37 THR B N 1 ATOM 3626 C CA . THR B 1 35 ? 109.164 -34.598 16.875 1.00 12.56 ? 37 THR B CA 1 ATOM 3627 C C . THR B 1 35 ? 109.182 -33.121 17.253 1.00 11.89 ? 37 THR B C 1 ATOM 3628 O O . THR B 1 35 ? 110.149 -32.409 16.979 1.00 11.45 ? 37 THR B O 1 ATOM 3629 C CB . THR B 1 35 ? 108.258 -34.789 15.643 1.00 14.14 ? 37 THR B CB 1 ATOM 3630 O OG1 . THR B 1 35 ? 108.306 -36.154 15.221 1.00 17.20 ? 37 THR B OG1 1 ATOM 3631 C CG2 . THR B 1 35 ? 108.725 -33.909 14.505 1.00 16.11 ? 37 THR B CG2 1 ATOM 3632 N N . HIS B 1 36 ? 108.103 -32.660 17.876 1.00 11.38 ? 38 HIS B N 1 ATOM 3633 C CA . HIS B 1 36 ? 107.980 -31.253 18.223 1.00 11.07 ? 38 HIS B CA 1 ATOM 3634 C C . HIS B 1 36 ? 108.796 -30.876 19.460 1.00 11.22 ? 38 HIS B C 1 ATOM 3635 O O . HIS B 1 36 ? 109.245 -29.740 19.588 1.00 11.15 ? 38 HIS B O 1 ATOM 3636 C CB . HIS B 1 36 ? 106.510 -30.866 18.391 1.00 11.44 ? 38 HIS B CB 1 ATOM 3637 C CG . HIS B 1 36 ? 105.709 -31.013 17.135 1.00 11.27 ? 38 HIS B CG 1 ATOM 3638 N ND1 . HIS B 1 36 ? 105.936 -30.241 16.017 1.00 11.41 ? 38 HIS B ND1 1 ATOM 3639 C CD2 . HIS B 1 36 ? 104.734 -31.889 16.796 1.00 11.43 ? 38 HIS B CD2 1 ATOM 3640 C CE1 . HIS B 1 36 ? 105.109 -30.609 15.055 1.00 11.29 ? 38 HIS B CE1 1 ATOM 3641 N NE2 . HIS B 1 36 ? 104.374 -31.613 15.500 1.00 11.37 ? 38 HIS B NE2 1 ATOM 3642 N N . LEU B 1 37 ? 109.025 -31.840 20.349 1.00 11.26 ? 39 LEU B N 1 ATOM 3643 C CA . LEU B 1 37 ? 109.953 -31.625 21.458 1.00 11.28 ? 39 LEU B CA 1 ATOM 3644 C C . LEU B 1 37 ? 111.329 -31.236 20.917 1.00 12.02 ? 39 LEU B C 1 ATOM 3645 O O . LEU B 1 37 ? 111.961 -30.295 21.404 1.00 12.04 ? 39 LEU B O 1 ATOM 3646 C CB . LEU B 1 37 ? 110.053 -32.877 22.334 1.00 10.63 ? 39 LEU B CB 1 ATOM 3647 C CG . LEU B 1 37 ? 110.816 -32.724 23.654 1.00 10.60 ? 39 LEU B CG 1 ATOM 3648 C CD1 . LEU B 1 37 ? 110.131 -31.721 24.578 1.00 9.88 ? 39 LEU B CD1 1 ATOM 3649 C CD2 . LEU B 1 37 ? 110.978 -34.068 24.344 1.00 9.87 ? 39 LEU B CD2 1 ATOM 3650 N N . ALA B 1 38 ? 111.759 -31.924 19.865 1.00 12.32 ? 40 ALA B N 1 ATOM 3651 C CA . ALA B 1 38 ? 113.086 -31.705 19.296 1.00 12.96 ? 40 ALA B CA 1 ATOM 3652 C C . ALA B 1 38 ? 113.148 -30.474 18.397 1.00 13.66 ? 40 ALA B C 1 ATOM 3653 O O . ALA B 1 38 ? 114.101 -29.701 18.462 1.00 13.23 ? 40 ALA B O 1 ATOM 3654 C CB . ALA B 1 38 ? 113.552 -32.938 18.537 1.00 13.88 ? 40 ALA B CB 1 ATOM 3655 N N A SER B 1 39 ? 112.123 -30.295 17.570 0.50 13.72 ? 41 SER B N 1 ATOM 3656 N N B SER B 1 39 ? 112.157 -30.319 17.524 0.50 13.49 ? 41 SER B N 1 ATOM 3657 C CA A SER B 1 39 ? 112.157 -29.271 16.532 0.50 14.35 ? 41 SER B CA 1 ATOM 3658 C CA B SER B 1 39 ? 112.179 -29.234 16.545 0.50 14.01 ? 41 SER B CA 1 ATOM 3659 C C A SER B 1 39 ? 111.655 -27.914 17.019 0.50 14.51 ? 41 SER B C 1 ATOM 3660 C C B SER B 1 39 ? 111.847 -27.893 17.188 0.50 14.05 ? 41 SER B C 1 ATOM 3661 O O A SER B 1 39 ? 111.973 -26.884 16.427 0.50 15.22 ? 41 SER B O 1 ATOM 3662 O O B SER B 1 39 ? 112.455 -26.872 16.870 0.50 14.44 ? 41 SER B O 1 ATOM 3663 C CB A SER B 1 39 ? 111.376 -29.723 15.293 0.50 14.24 ? 41 SER B CB 1 ATOM 3664 C CB B SER B 1 39 ? 111.203 -29.515 15.401 0.50 14.01 ? 41 SER B CB 1 ATOM 3665 O OG A SER B 1 39 ? 109.996 -29.880 15.579 0.50 14.24 ? 41 SER B OG 1 ATOM 3666 O OG B SER B 1 39 ? 111.432 -30.792 14.836 0.50 13.19 ? 41 SER B OG 1 ATOM 3667 N N . ASP B 1 40 ? 110.886 -27.905 18.105 1.00 14.33 ? 42 ASP B N 1 ATOM 3668 C CA . ASP B 1 40 ? 110.214 -26.682 18.523 1.00 15.04 ? 42 ASP B CA 1 ATOM 3669 C C . ASP B 1 40 ? 110.504 -26.236 19.956 1.00 14.85 ? 42 ASP B C 1 ATOM 3670 O O . ASP B 1 40 ? 110.612 -25.042 20.224 1.00 16.28 ? 42 ASP B O 1 ATOM 3671 C CB . ASP B 1 40 ? 108.711 -26.778 18.256 1.00 15.60 ? 42 ASP B CB 1 ATOM 3672 C CG . ASP B 1 40 ? 108.397 -26.897 16.772 1.00 17.37 ? 42 ASP B CG 1 ATOM 3673 O OD1 . ASP B 1 40 ? 108.626 -25.912 16.037 1.00 18.79 ? 42 ASP B OD1 1 ATOM 3674 O OD2 . ASP B 1 40 ? 107.995 -27.993 16.325 1.00 17.79 ? 42 ASP B OD2 1 ATOM 3675 N N . ILE B 1 41 ? 110.659 -27.189 20.867 1.00 13.71 ? 43 ILE B N 1 ATOM 3676 C CA . ILE B 1 41 ? 110.988 -26.853 22.251 1.00 13.23 ? 43 ILE B CA 1 ATOM 3677 C C . ILE B 1 41 ? 112.495 -26.753 22.485 1.00 13.17 ? 43 ILE B C 1 ATOM 3678 O O . ILE B 1 41 ? 112.987 -25.742 22.985 1.00 13.00 ? 43 ILE B O 1 ATOM 3679 C CB . ILE B 1 41 ? 110.362 -27.846 23.247 1.00 13.06 ? 43 ILE B CB 1 ATOM 3680 C CG1 . ILE B 1 41 ? 108.839 -27.842 23.112 1.00 13.03 ? 43 ILE B CG1 1 ATOM 3681 C CG2 . ILE B 1 41 ? 110.763 -27.493 24.673 1.00 12.55 ? 43 ILE B CG2 1 ATOM 3682 C CD1 . ILE B 1 41 ? 108.199 -26.509 23.441 1.00 13.30 ? 43 ILE B CD1 1 ATOM 3683 N N . ALA B 1 42 ? 113.227 -27.796 22.109 1.00 13.54 ? 44 ALA B N 1 ATOM 3684 C CA . ALA B 1 42 ? 114.654 -27.886 22.410 1.00 13.74 ? 44 ALA B CA 1 ATOM 3685 C C . ALA B 1 42 ? 115.429 -26.598 22.119 1.00 14.20 ? 44 ALA B C 1 ATOM 3686 O O . ALA B 1 42 ? 116.220 -26.153 22.949 1.00 13.97 ? 44 ALA B O 1 ATOM 3687 C CB . ALA B 1 42 ? 115.286 -29.064 21.684 1.00 13.58 ? 44 ALA B CB 1 ATOM 3688 N N . PRO B 1 43 ? 115.227 -26.012 20.926 1.00 14.10 ? 45 PRO B N 1 ATOM 3689 C CA . PRO B 1 43 ? 116.078 -24.897 20.510 1.00 14.74 ? 45 PRO B CA 1 ATOM 3690 C C . PRO B 1 43 ? 115.799 -23.607 21.280 1.00 14.89 ? 45 PRO B C 1 ATOM 3691 O O . PRO B 1 43 ? 116.580 -22.663 21.189 1.00 15.69 ? 45 PRO B O 1 ATOM 3692 C CB . PRO B 1 43 ? 115.721 -24.710 19.028 1.00 16.05 ? 45 PRO B CB 1 ATOM 3693 C CG . PRO B 1 43 ? 115.114 -26.006 18.608 1.00 15.64 ? 45 PRO B CG 1 ATOM 3694 C CD . PRO B 1 43 ? 114.391 -26.509 19.821 1.00 14.53 ? 45 PRO B CD 1 ATOM 3695 N N . VAL B 1 44 ? 114.703 -23.568 22.033 1.00 13.98 ? 46 VAL B N 1 ATOM 3696 C CA . VAL B 1 44 ? 114.322 -22.350 22.750 1.00 14.35 ? 46 VAL B CA 1 ATOM 3697 C C . VAL B 1 44 ? 114.303 -22.522 24.274 1.00 14.08 ? 46 VAL B C 1 ATOM 3698 O O . VAL B 1 44 ? 113.795 -21.662 24.995 1.00 14.54 ? 46 VAL B O 1 ATOM 3699 C CB . VAL B 1 44 ? 112.953 -21.816 22.281 1.00 14.57 ? 46 VAL B CB 1 ATOM 3700 C CG1 . VAL B 1 44 ? 112.994 -21.472 20.799 1.00 15.82 ? 46 VAL B CG1 1 ATOM 3701 C CG2 . VAL B 1 44 ? 111.856 -22.832 22.564 1.00 14.55 ? 46 VAL B CG2 1 ATOM 3702 N N . VAL B 1 45 ? 114.869 -23.620 24.767 1.00 12.42 ? 47 VAL B N 1 ATOM 3703 C CA . VAL B 1 45 ? 115.037 -23.791 26.211 1.00 12.24 ? 47 VAL B CA 1 ATOM 3704 C C . VAL B 1 45 ? 116.172 -22.910 26.730 1.00 12.68 ? 47 VAL B C 1 ATOM 3705 O O . VAL B 1 45 ? 117.269 -22.906 26.173 1.00 12.52 ? 47 VAL B O 1 ATOM 3706 C CB . VAL B 1 45 ? 115.302 -25.262 26.585 1.00 12.20 ? 47 VAL B CB 1 ATOM 3707 C CG1 . VAL B 1 45 ? 115.436 -25.414 28.094 1.00 12.23 ? 47 VAL B CG1 1 ATOM 3708 C CG2 . VAL B 1 45 ? 114.186 -26.150 26.056 1.00 12.15 ? 47 VAL B CG2 1 ATOM 3709 N N . ALA B 1 46 ? 115.886 -22.131 27.770 1.00 12.21 ? 48 ALA B N 1 ATOM 3710 C CA . ALA B 1 46 ? 116.854 -21.180 28.314 1.00 11.92 ? 48 ALA B CA 1 ATOM 3711 C C . ALA B 1 46 ? 117.853 -21.869 29.239 1.00 11.53 ? 48 ALA B C 1 ATOM 3712 O O . ALA B 1 46 ? 117.461 -22.564 30.177 1.00 10.71 ? 48 ALA B O 1 ATOM 3713 C CB . ALA B 1 46 ? 116.132 -20.063 29.058 1.00 11.67 ? 48 ALA B CB 1 ATOM 3714 N N . SER B 1 47 ? 119.136 -21.602 29.021 1.00 11.51 ? 49 SER B N 1 ATOM 3715 C CA . SER B 1 47 ? 120.202 -22.196 29.825 1.00 12.31 ? 49 SER B CA 1 ATOM 3716 C C . SER B 1 47 ? 120.623 -21.305 30.994 1.00 13.38 ? 49 SER B C 1 ATOM 3717 O O . SER B 1 47 ? 120.294 -20.120 31.040 1.00 14.52 ? 49 SER B O 1 ATOM 3718 C CB . SER B 1 47 ? 121.419 -22.497 28.949 1.00 12.79 ? 49 SER B CB 1 ATOM 3719 O OG . SER B 1 47 ? 122.106 -21.303 28.611 1.00 12.21 ? 49 SER B OG 1 ATOM 3720 N N . VAL B 1 48 ? 121.383 -21.880 31.921 1.00 14.37 ? 50 VAL B N 1 ATOM 3721 C CA . VAL B 1 48 ? 121.957 -21.128 33.033 1.00 15.25 ? 50 VAL B CA 1 ATOM 3722 C C . VAL B 1 48 ? 122.917 -20.046 32.539 1.00 16.57 ? 50 VAL B C 1 ATOM 3723 O O . VAL B 1 48 ? 122.904 -18.920 33.039 1.00 17.32 ? 50 VAL B O 1 ATOM 3724 C CB . VAL B 1 48 ? 122.689 -22.062 34.016 1.00 15.39 ? 50 VAL B CB 1 ATOM 3725 C CG1 . VAL B 1 48 ? 123.632 -21.271 34.912 1.00 14.21 ? 50 VAL B CG1 1 ATOM 3726 C CG2 . VAL B 1 48 ? 121.686 -22.852 34.844 1.00 14.61 ? 50 VAL B CG2 1 ATOM 3727 N N . THR B 1 49 ? 123.724 -20.380 31.535 1.00 16.98 ? 51 THR B N 1 ATOM 3728 C CA . THR B 1 49 ? 124.627 -19.407 30.923 1.00 18.41 ? 51 THR B CA 1 ATOM 3729 C C . THR B 1 49 ? 123.842 -18.210 30.403 1.00 19.44 ? 51 THR B C 1 ATOM 3730 O O . THR B 1 49 ? 124.163 -17.060 30.704 1.00 20.04 ? 51 THR B O 1 ATOM 3731 C CB . THR B 1 49 ? 125.418 -20.023 29.751 1.00 18.53 ? 51 THR B CB 1 ATOM 3732 O OG1 . THR B 1 49 ? 126.135 -21.177 30.206 1.00 18.82 ? 51 THR B OG1 1 ATOM 3733 C CG2 . THR B 1 49 ? 126.409 -19.008 29.187 1.00 18.69 ? 51 THR B CG2 1 ATOM 3734 N N . GLN B 1 50 ? 122.801 -18.499 29.630 1.00 19.19 ? 52 GLN B N 1 ATOM 3735 C CA . GLN B 1 50 ? 121.939 -17.476 29.057 1.00 21.42 ? 52 GLN B CA 1 ATOM 3736 C C . GLN B 1 50 ? 121.391 -16.523 30.116 1.00 21.45 ? 52 GLN B C 1 ATOM 3737 O O . GLN B 1 50 ? 121.465 -15.303 29.963 1.00 21.85 ? 52 GLN B O 1 ATOM 3738 C CB . GLN B 1 50 ? 120.780 -18.141 28.318 1.00 24.36 ? 52 GLN B CB 1 ATOM 3739 C CG . GLN B 1 50 ? 120.160 -17.302 27.217 1.00 28.67 ? 52 GLN B CG 1 ATOM 3740 C CD . GLN B 1 50 ? 119.421 -18.155 26.204 1.00 33.86 ? 52 GLN B CD 1 ATOM 3741 O OE1 . GLN B 1 50 ? 119.515 -19.385 26.226 1.00 35.00 ? 52 GLN B OE1 1 ATOM 3742 N NE2 . GLN B 1 50 ? 118.692 -17.508 25.302 1.00 34.77 ? 52 GLN B NE2 1 ATOM 3743 N N . LEU B 1 51 ? 120.800 -17.084 31.166 1.00 19.39 ? 53 LEU B N 1 ATOM 3744 C CA . LEU B 1 51 ? 120.108 -16.282 32.170 1.00 20.43 ? 53 LEU B CA 1 ATOM 3745 C C . LEU B 1 51 ? 121.073 -15.647 33.175 1.00 21.47 ? 53 LEU B C 1 ATOM 3746 O O . LEU B 1 51 ? 120.707 -14.714 33.887 1.00 22.55 ? 53 LEU B O 1 ATOM 3747 C CB . LEU B 1 51 ? 119.047 -17.117 32.895 1.00 18.46 ? 53 LEU B CB 1 ATOM 3748 C CG . LEU B 1 51 ? 117.949 -17.750 32.036 1.00 17.73 ? 53 LEU B CG 1 ATOM 3749 C CD1 . LEU B 1 51 ? 116.858 -18.358 32.909 1.00 17.83 ? 53 LEU B CD1 1 ATOM 3750 C CD2 . LEU B 1 51 ? 117.352 -16.732 31.078 1.00 17.78 ? 53 LEU B CD2 1 ATOM 3751 N N . SER B 1 52 ? 122.305 -16.148 33.218 1.00 22.13 ? 54 SER B N 1 ATOM 3752 C CA . SER B 1 52 ? 123.315 -15.650 34.152 1.00 22.35 ? 54 SER B CA 1 ATOM 3753 C C . SER B 1 52 ? 123.744 -14.225 33.814 1.00 23.68 ? 54 SER B C 1 ATOM 3754 O O . SER B 1 52 ? 124.235 -13.491 34.674 1.00 24.60 ? 54 SER B O 1 ATOM 3755 C CB . SER B 1 52 ? 124.542 -16.568 34.159 1.00 24.04 ? 54 SER B CB 1 ATOM 3756 O OG . SER B 1 52 ? 124.316 -17.717 34.954 1.00 24.96 ? 54 SER B OG 1 ATOM 3757 N N . ASN B 1 53 ? 123.590 -13.852 32.549 1.00 22.84 ? 55 ASN B N 1 ATOM 3758 C CA . ASN B 1 53 ? 123.918 -12.506 32.106 1.00 24.56 ? 55 ASN B CA 1 ATOM 3759 C C . ASN B 1 53 ? 122.658 -11.763 31.695 1.00 23.60 ? 55 ASN B C 1 ATOM 3760 O O . ASN B 1 53 ? 121.929 -12.211 30.811 1.00 24.13 ? 55 ASN B O 1 ATOM 3761 C CB . ASN B 1 53 ? 124.898 -12.545 30.927 1.00 24.15 ? 55 ASN B CB 1 ATOM 3762 C CG . ASN B 1 53 ? 125.959 -13.619 31.078 1.00 23.92 ? 55 ASN B CG 1 ATOM 3763 O OD1 . ASN B 1 53 ? 126.763 -13.590 32.008 1.00 23.49 ? 55 ASN B OD1 1 ATOM 3764 N ND2 . ASN B 1 53 ? 125.991 -14.552 30.135 1.00 26.55 ? 55 ASN B ND2 1 ATOM 3765 N N . VAL B 1 54 ? 122.411 -10.618 32.323 1.00 24.16 ? 56 VAL B N 1 ATOM 3766 C CA . VAL B 1 54 ? 121.271 -9.789 31.952 1.00 23.76 ? 56 VAL B CA 1 ATOM 3767 C C . VAL B 1 54 ? 121.233 -9.567 30.444 1.00 24.14 ? 56 VAL B C 1 ATOM 3768 O O . VAL B 1 54 ? 120.161 -9.486 29.843 1.00 23.52 ? 56 VAL B O 1 ATOM 3769 C CB . VAL B 1 54 ? 121.295 -8.428 32.671 1.00 24.91 ? 56 VAL B CB 1 ATOM 3770 C CG1 . VAL B 1 54 ? 120.279 -7.482 32.045 1.00 24.21 ? 56 VAL B CG1 1 ATOM 3771 C CG2 . VAL B 1 54 ? 121.021 -8.611 34.158 1.00 24.28 ? 56 VAL B CG2 1 ATOM 3772 N N . ALA B 1 55 ? 122.412 -9.508 29.833 1.00 23.18 ? 57 ALA B N 1 ATOM 3773 C CA . ALA B 1 55 ? 122.530 -9.151 28.425 1.00 23.36 ? 57 ALA B CA 1 ATOM 3774 C C . ALA B 1 55 ? 121.925 -10.203 27.500 1.00 22.91 ? 57 ALA B C 1 ATOM 3775 O O . ALA B 1 55 ? 121.442 -9.878 26.416 1.00 22.45 ? 57 ALA B O 1 ATOM 3776 C CB . ALA B 1 55 ? 123.986 -8.897 28.063 1.00 24.01 ? 57 ALA B CB 1 ATOM 3777 N N . THR B 1 56 ? 121.967 -11.465 27.920 1.00 21.67 ? 58 THR B N 1 ATOM 3778 C CA . THR B 1 56 ? 121.595 -12.574 27.040 1.00 20.83 ? 58 THR B CA 1 ATOM 3779 C C . THR B 1 56 ? 120.270 -13.221 27.431 1.00 21.89 ? 58 THR B C 1 ATOM 3780 O O . THR B 1 56 ? 119.888 -14.253 26.880 1.00 21.91 ? 58 THR B O 1 ATOM 3781 C CB . THR B 1 56 ? 122.687 -13.659 27.000 1.00 20.51 ? 58 THR B CB 1 ATOM 3782 O OG1 . THR B 1 56 ? 123.117 -13.956 28.334 1.00 20.69 ? 58 THR B OG1 1 ATOM 3783 C CG2 . THR B 1 56 ? 123.881 -13.184 26.180 1.00 19.71 ? 58 THR B CG2 1 ATOM 3784 N N . GLN B 1 57 ? 119.569 -12.613 28.381 1.00 22.04 ? 59 GLN B N 1 ATOM 3785 C CA . GLN B 1 57 ? 118.247 -13.095 28.767 1.00 23.76 ? 59 GLN B CA 1 ATOM 3786 C C . GLN B 1 57 ? 117.227 -12.872 27.653 1.00 22.25 ? 59 GLN B C 1 ATOM 3787 O O . GLN B 1 57 ? 117.158 -11.788 27.077 1.00 24.52 ? 59 GLN B O 1 ATOM 3788 C CB . GLN B 1 57 ? 117.796 -12.432 30.068 1.00 23.54 ? 59 GLN B CB 1 ATOM 3789 C CG . GLN B 1 57 ? 118.667 -12.808 31.256 1.00 25.18 ? 59 GLN B CG 1 ATOM 3790 C CD . GLN B 1 57 ? 118.335 -12.023 32.506 1.00 28.07 ? 59 GLN B CD 1 ATOM 3791 O OE1 . GLN B 1 57 ? 118.846 -12.314 33.589 1.00 30.50 ? 59 GLN B OE1 1 ATOM 3792 N NE2 . GLN B 1 57 ? 117.484 -11.014 32.363 1.00 25.99 ? 59 GLN B NE2 1 ATOM 3793 N N . PRO B 1 58 ? 116.443 -13.913 27.334 1.00 22.00 ? 60 PRO B N 1 ATOM 3794 C CA . PRO B 1 58 ? 115.529 -13.898 26.199 1.00 21.00 ? 60 PRO B CA 1 ATOM 3795 C C . PRO B 1 58 ? 114.216 -13.191 26.520 1.00 21.64 ? 60 PRO B C 1 ATOM 3796 O O . PRO B 1 58 ? 113.904 -12.963 27.687 1.00 22.82 ? 60 PRO B O 1 ATOM 3797 C CB . PRO B 1 58 ? 115.264 -15.381 25.965 1.00 20.36 ? 60 PRO B CB 1 ATOM 3798 C CG . PRO B 1 58 ? 115.324 -15.970 27.331 1.00 19.67 ? 60 PRO B CG 1 ATOM 3799 C CD . PRO B 1 58 ? 116.362 -15.178 28.087 1.00 20.99 ? 60 PRO B CD 1 ATOM 3800 N N . LEU B 1 59 ? 113.435 -12.897 25.486 1.00 20.73 ? 61 LEU B N 1 ATOM 3801 C CA . LEU B 1 59 ? 112.129 -12.270 25.654 1.00 22.00 ? 61 LEU B CA 1 ATOM 3802 C C . LEU B 1 59 ? 111.196 -13.171 26.458 1.00 21.42 ? 61 LEU B C 1 ATOM 3803 O O . LEU B 1 59 ? 110.561 -12.729 27.416 1.00 20.27 ? 61 LEU B O 1 ATOM 3804 C CB . LEU B 1 59 ? 111.512 -11.970 24.289 1.00 24.53 ? 61 LEU B CB 1 ATOM 3805 C CG . LEU B 1 59 ? 110.370 -10.953 24.232 1.00 27.18 ? 61 LEU B CG 1 ATOM 3806 C CD1 . LEU B 1 59 ? 110.686 -9.731 25.082 1.00 27.97 ? 61 LEU B CD1 1 ATOM 3807 C CD2 . LEU B 1 59 ? 110.105 -10.552 22.790 1.00 27.82 ? 61 LEU B CD2 1 ATOM 3808 N N . VAL B 1 60 ? 111.101 -14.431 26.045 1.00 18.63 ? 62 VAL B N 1 ATOM 3809 C CA . VAL B 1 60 ? 110.420 -15.450 26.831 1.00 16.90 ? 62 VAL B CA 1 ATOM 3810 C C . VAL B 1 60 ? 111.400 -16.554 27.215 1.00 15.69 ? 62 VAL B C 1 ATOM 3811 O O . VAL B 1 60 ? 112.049 -17.148 26.353 1.00 16.70 ? 62 VAL B O 1 ATOM 3812 C CB . VAL B 1 60 ? 109.227 -16.055 26.066 1.00 16.97 ? 62 VAL B CB 1 ATOM 3813 C CG1 . VAL B 1 60 ? 108.533 -17.116 26.909 1.00 17.15 ? 62 VAL B CG1 1 ATOM 3814 C CG2 . VAL B 1 60 ? 108.244 -14.964 25.669 1.00 18.50 ? 62 VAL B CG2 1 ATOM 3815 N N . ALA B 1 61 ? 111.552 -16.781 28.515 1.00 14.18 ? 63 ALA B N 1 ATOM 3816 C CA . ALA B 1 61 ? 112.362 -17.887 29.003 1.00 13.48 ? 63 ALA B CA 1 ATOM 3817 C C . ALA B 1 61 ? 111.507 -19.138 29.179 1.00 13.63 ? 63 ALA B C 1 ATOM 3818 O O . ALA B 1 61 ? 110.428 -19.090 29.769 1.00 13.78 ? 63 ALA B O 1 ATOM 3819 C CB . ALA B 1 61 ? 113.041 -17.513 30.309 1.00 12.65 ? 63 ALA B CB 1 ATOM 3820 N N . LEU B 1 62 ? 111.982 -20.256 28.642 1.00 12.55 ? 64 LEU B N 1 ATOM 3821 C CA . LEU B 1 62 ? 111.233 -21.499 28.714 1.00 11.41 ? 64 LEU B CA 1 ATOM 3822 C C . LEU B 1 62 ? 112.094 -22.605 29.315 1.00 10.46 ? 64 LEU B C 1 ATOM 3823 O O . LEU B 1 62 ? 113.248 -22.783 28.922 1.00 10.50 ? 64 LEU B O 1 ATOM 3824 C CB . LEU B 1 62 ? 110.729 -21.901 27.324 1.00 11.49 ? 64 LEU B CB 1 ATOM 3825 C CG . LEU B 1 62 ? 109.866 -23.162 27.226 1.00 11.58 ? 64 LEU B CG 1 ATOM 3826 C CD1 . LEU B 1 62 ? 109.002 -23.130 25.973 1.00 12.86 ? 64 LEU B CD1 1 ATOM 3827 C CD2 . LEU B 1 62 ? 110.733 -24.411 27.244 1.00 11.82 ? 64 LEU B CD2 1 ATOM 3828 N N . ASN B 1 63 ? 111.553 -23.282 30.325 1.00 8.89 ? 65 ASN B N 1 ATOM 3829 C CA . ASN B 1 63 ? 112.120 -24.531 30.830 1.00 8.27 ? 65 ASN B CA 1 ATOM 3830 C C . ASN B 1 63 ? 111.070 -25.636 30.734 1.00 7.87 ? 65 ASN B C 1 ATOM 3831 O O . ASN B 1 63 ? 109.874 -25.358 30.647 1.00 7.53 ? 65 ASN B O 1 ATOM 3832 C CB . ASN B 1 63 ? 112.555 -24.370 32.294 1.00 8.06 ? 65 ASN B CB 1 ATOM 3833 C CG . ASN B 1 63 ? 113.965 -23.812 32.437 1.00 8.29 ? 65 ASN B CG 1 ATOM 3834 O OD1 . ASN B 1 63 ? 114.536 -23.827 33.528 1.00 8.01 ? 65 ASN B OD1 1 ATOM 3835 N ND2 . ASN B 1 63 ? 114.536 -23.331 31.337 1.00 7.92 ? 65 ASN B ND2 1 ATOM 3836 N N . ILE B 1 64 ? 111.506 -26.889 30.778 1.00 7.58 ? 66 ILE B N 1 ATOM 3837 C CA . ILE B 1 64 ? 110.565 -28.003 30.728 1.00 7.38 ? 66 ILE B CA 1 ATOM 3838 C C . ILE B 1 64 ? 111.046 -29.186 31.568 1.00 7.80 ? 66 ILE B C 1 ATOM 3839 O O . ILE B 1 64 ? 112.243 -29.463 31.637 1.00 8.94 ? 66 ILE B O 1 ATOM 3840 C CB . ILE B 1 64 ? 110.304 -28.446 29.273 1.00 7.41 ? 66 ILE B CB 1 ATOM 3841 C CG1 . ILE B 1 64 ? 109.205 -29.511 29.215 1.00 7.29 ? 66 ILE B CG1 1 ATOM 3842 C CG2 . ILE B 1 64 ? 111.590 -28.929 28.619 1.00 7.44 ? 66 ILE B CG2 1 ATOM 3843 C CD1 . ILE B 1 64 ? 108.718 -29.815 27.810 1.00 7.13 ? 66 ILE B CD1 1 ATOM 3844 N N . ALA B 1 65 ? 110.116 -29.853 32.243 1.00 7.93 ? 67 ALA B N 1 ATOM 3845 C CA . ALA B 1 65 ? 110.469 -30.959 33.128 1.00 7.75 ? 67 ALA B CA 1 ATOM 3846 C C . ALA B 1 65 ? 109.437 -32.071 33.023 1.00 7.81 ? 67 ALA B C 1 ATOM 3847 O O . ALA B 1 65 ? 108.281 -31.826 32.682 1.00 7.30 ? 67 ALA B O 1 ATOM 3848 C CB . ALA B 1 65 ? 110.588 -30.474 34.568 1.00 7.72 ? 67 ALA B CB 1 ATOM 3849 N N . PHE B 1 66 ? 109.867 -33.298 33.290 1.00 8.02 ? 68 PHE B N 1 ATOM 3850 C CA . PHE B 1 66 ? 108.996 -34.448 33.114 1.00 8.31 ? 68 PHE B CA 1 ATOM 3851 C C . PHE B 1 66 ? 108.833 -35.233 34.402 1.00 8.41 ? 68 PHE B C 1 ATOM 3852 O O . PHE B 1 66 ? 109.778 -35.380 35.179 1.00 8.08 ? 68 PHE B O 1 ATOM 3853 C CB . PHE B 1 66 ? 109.522 -35.353 32.006 1.00 8.47 ? 68 PHE B CB 1 ATOM 3854 C CG . PHE B 1 66 ? 109.538 -34.699 30.657 1.00 9.03 ? 68 PHE B CG 1 ATOM 3855 C CD1 . PHE B 1 66 ? 110.619 -33.926 30.261 1.00 9.20 ? 68 PHE B CD1 1 ATOM 3856 C CD2 . PHE B 1 66 ? 108.452 -34.816 29.804 1.00 9.38 ? 68 PHE B CD2 1 ATOM 3857 C CE1 . PHE B 1 66 ? 110.641 -33.332 29.013 1.00 9.60 ? 68 PHE B CE1 1 ATOM 3858 C CE2 . PHE B 1 66 ? 108.455 -34.198 28.566 1.00 10.05 ? 68 PHE B CE2 1 ATOM 3859 C CZ . PHE B 1 66 ? 109.557 -33.465 28.166 1.00 10.20 ? 68 PHE B CZ 1 ATOM 3860 N N . SER B 1 67 ? 107.625 -35.736 34.621 1.00 8.45 ? 69 SER B N 1 ATOM 3861 C CA . SER B 1 67 ? 107.376 -36.649 35.721 1.00 8.42 ? 69 SER B CA 1 ATOM 3862 C C . SER B 1 67 ? 107.847 -38.041 35.331 1.00 8.72 ? 69 SER B C 1 ATOM 3863 O O . SER B 1 67 ? 108.178 -38.299 34.171 1.00 8.33 ? 69 SER B O 1 ATOM 3864 C CB . SER B 1 67 ? 105.885 -36.696 36.052 1.00 8.35 ? 69 SER B CB 1 ATOM 3865 O OG . SER B 1 67 ? 105.178 -37.382 35.036 1.00 8.20 ? 69 SER B OG 1 ATOM 3866 N N . ASN B 1 68 ? 107.854 -38.941 36.304 1.00 8.74 ? 70 ASN B N 1 ATOM 3867 C CA . ASN B 1 68 ? 108.143 -40.339 36.035 1.00 9.79 ? 70 ASN B CA 1 ATOM 3868 C C . ASN B 1 68 ? 107.244 -40.901 34.933 1.00 9.27 ? 70 ASN B C 1 ATOM 3869 O O . ASN B 1 68 ? 107.724 -41.536 33.993 1.00 9.28 ? 70 ASN B O 1 ATOM 3870 C CB . ASN B 1 68 ? 108.001 -41.166 37.315 1.00 9.91 ? 70 ASN B CB 1 ATOM 3871 C CG . ASN B 1 68 ? 108.215 -42.648 37.078 1.00 11.02 ? 70 ASN B CG 1 ATOM 3872 O OD1 . ASN B 1 68 ? 109.328 -43.087 36.780 1.00 11.41 ? 70 ASN B OD1 1 ATOM 3873 N ND2 . ASN B 1 68 ? 107.146 -43.430 37.212 1.00 10.90 ? 70 ASN B ND2 1 ATOM 3874 N N . THR B 1 69 ? 105.942 -40.640 35.031 1.00 9.40 ? 71 THR B N 1 ATOM 3875 C CA . THR B 1 69 ? 104.999 -41.182 34.058 1.00 9.38 ? 71 THR B CA 1 ATOM 3876 C C . THR B 1 69 ? 105.143 -40.521 32.691 1.00 9.62 ? 71 THR B C 1 ATOM 3877 O O . THR B 1 69 ? 104.791 -41.110 31.670 1.00 10.56 ? 71 THR B O 1 ATOM 3878 C CB . THR B 1 69 ? 103.537 -41.077 34.535 1.00 9.58 ? 71 THR B CB 1 ATOM 3879 O OG1 . THR B 1 69 ? 103.250 -39.728 34.925 1.00 10.12 ? 71 THR B OG1 1 ATOM 3880 C CG2 . THR B 1 69 ? 103.292 -42.014 35.704 1.00 9.77 ? 71 THR B CG2 1 ATOM 3881 N N . GLY B 1 70 ? 105.663 -39.298 32.673 1.00 9.34 ? 72 GLY B N 1 ATOM 3882 C CA . GLY B 1 70 ? 105.976 -38.623 31.417 1.00 9.55 ? 72 GLY B CA 1 ATOM 3883 C C . GLY B 1 70 ? 107.154 -39.260 30.704 1.00 9.88 ? 72 GLY B C 1 ATOM 3884 O O . GLY B 1 70 ? 107.094 -39.538 29.505 1.00 9.57 ? 72 GLY B O 1 ATOM 3885 N N . LEU B 1 71 ? 108.222 -39.519 31.451 1.00 10.07 ? 73 LEU B N 1 ATOM 3886 C CA . LEU B 1 71 ? 109.356 -40.271 30.922 1.00 9.99 ? 73 LEU B CA 1 ATOM 3887 C C . LEU B 1 71 ? 108.921 -41.636 30.391 1.00 9.98 ? 73 LEU B C 1 ATOM 3888 O O . LEU B 1 71 ? 109.336 -42.048 29.309 1.00 10.19 ? 73 LEU B O 1 ATOM 3889 C CB . LEU B 1 71 ? 110.449 -40.431 31.984 1.00 9.68 ? 73 LEU B CB 1 ATOM 3890 C CG . LEU B 1 71 ? 111.203 -39.155 32.386 1.00 9.97 ? 73 LEU B CG 1 ATOM 3891 C CD1 . LEU B 1 71 ? 112.306 -39.460 33.387 1.00 10.33 ? 73 LEU B CD1 1 ATOM 3892 C CD2 . LEU B 1 71 ? 111.768 -38.423 31.177 1.00 9.52 ? 73 LEU B CD2 1 ATOM 3893 N N . LEU B 1 72 ? 108.070 -42.327 31.143 1.00 10.24 ? 74 LEU B N 1 ATOM 3894 C CA . LEU B 1 72 ? 107.572 -43.633 30.710 1.00 10.60 ? 74 LEU B CA 1 ATOM 3895 C C . LEU B 1 72 ? 106.743 -43.526 29.432 1.00 10.54 ? 74 LEU B C 1 ATOM 3896 O O . LEU B 1 72 ? 106.856 -44.369 28.541 1.00 10.37 ? 74 LEU B O 1 ATOM 3897 C CB . LEU B 1 72 ? 106.774 -44.318 31.821 1.00 11.02 ? 74 LEU B CB 1 ATOM 3898 C CG . LEU B 1 72 ? 107.623 -44.809 32.998 1.00 11.79 ? 74 LEU B CG 1 ATOM 3899 C CD1 . LEU B 1 72 ? 106.763 -45.417 34.097 1.00 13.04 ? 74 LEU B CD1 1 ATOM 3900 C CD2 . LEU B 1 72 ? 108.680 -45.794 32.523 1.00 12.07 ? 74 LEU B CD2 1 ATOM 3901 N N . ALA B 1 73 ? 105.947 -42.465 29.329 1.00 10.01 ? 75 ALA B N 1 ATOM 3902 C CA . ALA B 1 73 ? 105.159 -42.208 28.130 1.00 10.32 ? 75 ALA B CA 1 ATOM 3903 C C . ALA B 1 73 ? 106.053 -42.036 26.906 1.00 10.53 ? 75 ALA B C 1 ATOM 3904 O O . ALA B 1 73 ? 105.659 -42.364 25.787 1.00 11.20 ? 75 ALA B O 1 ATOM 3905 C CB . ALA B 1 73 ? 104.280 -40.978 28.324 1.00 10.28 ? 75 ALA B CB 1 ATOM 3906 N N . LEU B 1 74 ? 107.247 -41.496 27.126 1.00 10.76 ? 76 LEU B N 1 ATOM 3907 C CA . LEU B 1 74 ? 108.210 -41.272 26.052 1.00 11.26 ? 76 LEU B CA 1 ATOM 3908 C C . LEU B 1 74 ? 109.052 -42.513 25.769 1.00 12.06 ? 76 LEU B C 1 ATOM 3909 O O . LEU B 1 74 ? 109.913 -42.503 24.888 1.00 13.02 ? 76 LEU B O 1 ATOM 3910 C CB . LEU B 1 74 ? 109.126 -40.094 26.399 1.00 11.17 ? 76 LEU B CB 1 ATOM 3911 C CG . LEU B 1 74 ? 108.453 -38.722 26.442 1.00 11.40 ? 76 LEU B CG 1 ATOM 3912 C CD1 . LEU B 1 74 ? 109.425 -37.649 26.909 1.00 11.22 ? 76 LEU B CD1 1 ATOM 3913 C CD2 . LEU B 1 74 ? 107.873 -38.376 25.078 1.00 12.24 ? 76 LEU B CD2 1 ATOM 3914 N N . GLY B 1 75 ? 108.788 -43.587 26.505 1.00 11.94 ? 77 GLY B N 1 ATOM 3915 C CA . GLY B 1 75 ? 109.525 -44.831 26.319 1.00 12.16 ? 77 GLY B CA 1 ATOM 3916 C C . GLY B 1 75 ? 110.880 -44.808 26.999 1.00 12.62 ? 77 GLY B C 1 ATOM 3917 O O . GLY B 1 75 ? 111.742 -45.642 26.720 1.00 13.20 ? 77 GLY B O 1 ATOM 3918 N N . VAL B 1 76 ? 111.069 -43.858 27.906 1.00 12.18 ? 78 VAL B N 1 ATOM 3919 C CA . VAL B 1 76 ? 112.307 -43.785 28.665 1.00 12.76 ? 78 VAL B CA 1 ATOM 3920 C C . VAL B 1 76 ? 112.166 -44.542 29.978 1.00 13.23 ? 78 VAL B C 1 ATOM 3921 O O . VAL B 1 76 ? 111.536 -44.059 30.920 1.00 12.88 ? 78 VAL B O 1 ATOM 3922 C CB . VAL B 1 76 ? 112.720 -42.328 28.941 1.00 12.51 ? 78 VAL B CB 1 ATOM 3923 C CG1 . VAL B 1 76 ? 114.069 -42.288 29.642 1.00 12.84 ? 78 VAL B CG1 1 ATOM 3924 C CG2 . VAL B 1 76 ? 112.769 -41.541 27.640 1.00 12.07 ? 78 VAL B CG2 1 ATOM 3925 N N . THR B 1 77 ? 112.740 -45.741 30.025 1.00 13.52 ? 79 THR B N 1 ATOM 3926 C CA . THR B 1 77 ? 112.541 -46.646 31.151 1.00 14.49 ? 79 THR B CA 1 ATOM 3927 C C . THR B 1 77 ? 113.750 -46.660 32.082 1.00 14.33 ? 79 THR B C 1 ATOM 3928 O O . THR B 1 77 ? 113.787 -47.416 33.055 1.00 14.19 ? 79 THR B O 1 ATOM 3929 C CB . THR B 1 77 ? 112.271 -48.083 30.669 1.00 15.16 ? 79 THR B CB 1 ATOM 3930 O OG1 . THR B 1 77 ? 113.319 -48.492 29.782 1.00 15.35 ? 79 THR B OG1 1 ATOM 3931 C CG2 . THR B 1 77 ? 110.940 -48.160 29.938 1.00 15.60 ? 79 THR B CG2 1 ATOM 3932 N N . ASP B 1 78 ? 114.740 -45.827 31.776 1.00 14.54 ? 80 ASP B N 1 ATOM 3933 C CA . ASP B 1 78 ? 115.970 -45.774 32.560 1.00 14.45 ? 80 ASP B CA 1 ATOM 3934 C C . ASP B 1 78 ? 115.667 -45.383 33.997 1.00 13.91 ? 80 ASP B C 1 ATOM 3935 O O . ASP B 1 78 ? 114.780 -44.568 34.251 1.00 13.92 ? 80 ASP B O 1 ATOM 3936 C CB . ASP B 1 78 ? 116.949 -44.765 31.958 1.00 14.92 ? 80 ASP B CB 1 ATOM 3937 C CG . ASP B 1 78 ? 117.344 -45.112 30.538 1.00 16.64 ? 80 ASP B CG 1 ATOM 3938 O OD1 . ASP B 1 78 ? 117.006 -46.226 30.076 1.00 18.89 ? 80 ASP B OD1 1 ATOM 3939 O OD2 . ASP B 1 78 ? 118.002 -44.274 29.888 1.00 15.68 ? 80 ASP B OD2 1 ATOM 3940 N N . ASN B 1 79 ? 116.414 -45.961 34.933 1.00 13.65 ? 81 ASN B N 1 ATOM 3941 C CA . ASN B 1 79 ? 116.308 -45.589 36.339 1.00 14.04 ? 81 ASN B CA 1 ATOM 3942 C C . ASN B 1 79 ? 117.102 -44.318 36.633 1.00 14.25 ? 81 ASN B C 1 ATOM 3943 O O . ASN B 1 79 ? 118.320 -44.285 36.457 1.00 12.27 ? 81 ASN B O 1 ATOM 3944 C CB . ASN B 1 79 ? 116.802 -46.733 37.231 1.00 15.65 ? 81 ASN B CB 1 ATOM 3945 C CG . ASN B 1 79 ? 116.487 -46.509 38.700 1.00 18.24 ? 81 ASN B CG 1 ATOM 3946 O OD1 . ASN B 1 79 ? 116.233 -45.383 39.129 1.00 18.29 ? 81 ASN B OD1 1 ATOM 3947 N ND2 . ASN B 1 79 ? 116.511 -47.584 39.482 1.00 20.16 ? 81 ASN B ND2 1 ATOM 3948 N N . LEU B 1 80 ? 116.403 -43.270 37.062 1.00 13.30 ? 82 LEU B N 1 ATOM 3949 C CA . LEU B 1 80 ? 117.032 -41.976 37.326 1.00 14.12 ? 82 LEU B CA 1 ATOM 3950 C C . LEU B 1 80 ? 117.680 -41.953 38.710 1.00 14.01 ? 82 LEU B C 1 ATOM 3951 O O . LEU B 1 80 ? 118.365 -40.993 39.069 1.00 14.32 ? 82 LEU B O 1 ATOM 3952 C CB . LEU B 1 80 ? 115.998 -40.850 37.217 1.00 14.48 ? 82 LEU B CB 1 ATOM 3953 C CG . LEU B 1 80 ? 115.668 -40.276 35.835 1.00 15.70 ? 82 LEU B CG 1 ATOM 3954 C CD1 . LEU B 1 80 ? 116.750 -39.306 35.386 1.00 19.64 ? 82 LEU B CD1 1 ATOM 3955 C CD2 . LEU B 1 80 ? 115.458 -41.366 34.793 1.00 15.65 ? 82 LEU B CD2 1 ATOM 3956 N N . GLY B 1 81 ? 117.440 -43.001 39.491 1.00 13.17 ? 83 GLY B N 1 ATOM 3957 C CA . GLY B 1 81 ? 118.110 -43.172 40.779 1.00 13.28 ? 83 GLY B CA 1 ATOM 3958 C C . GLY B 1 81 ? 117.405 -42.499 41.942 1.00 13.00 ? 83 GLY B C 1 ATOM 3959 O O . GLY B 1 81 ? 117.969 -42.364 43.029 1.00 13.06 ? 83 GLY B O 1 ATOM 3960 N N . ASP B 1 82 ? 116.162 -42.087 41.723 1.00 12.89 ? 84 ASP B N 1 ATOM 3961 C CA . ASP B 1 82 ? 115.402 -41.394 42.758 1.00 11.93 ? 84 ASP B CA 1 ATOM 3962 C C . ASP B 1 82 ? 114.030 -42.030 42.954 1.00 11.73 ? 84 ASP B C 1 ATOM 3963 O O . ASP B 1 82 ? 113.131 -41.839 42.140 1.00 11.83 ? 84 ASP B O 1 ATOM 3964 C CB . ASP B 1 82 ? 115.258 -39.911 42.404 1.00 11.63 ? 84 ASP B CB 1 ATOM 3965 C CG . ASP B 1 82 ? 114.914 -39.056 43.607 1.00 11.51 ? 84 ASP B CG 1 ATOM 3966 O OD1 . ASP B 1 82 ? 113.750 -39.100 44.048 1.00 11.18 ? 84 ASP B OD1 1 ATOM 3967 O OD2 . ASP B 1 82 ? 115.808 -38.340 44.106 1.00 11.30 ? 84 ASP B OD2 1 ATOM 3968 N N A SER B 1 83 ? 113.883 -42.794 44.033 0.50 11.70 ? 85 SER B N 1 ATOM 3969 N N B SER B 1 83 ? 113.869 -42.760 44.055 0.50 11.59 ? 85 SER B N 1 ATOM 3970 C CA A SER B 1 83 ? 112.643 -43.513 44.302 0.50 11.74 ? 85 SER B CA 1 ATOM 3971 C CA B SER B 1 83 ? 112.649 -43.523 44.308 0.50 11.54 ? 85 SER B CA 1 ATOM 3972 C C A SER B 1 83 ? 111.469 -42.561 44.495 0.50 11.31 ? 85 SER B C 1 ATOM 3973 C C B SER B 1 83 ? 111.448 -42.627 44.612 0.50 11.32 ? 85 SER B C 1 ATOM 3974 O O A SER B 1 83 ? 110.362 -42.823 44.023 0.50 11.59 ? 85 SER B O 1 ATOM 3975 O O B SER B 1 83 ? 110.307 -42.985 44.315 0.50 11.81 ? 85 SER B O 1 ATOM 3976 C CB A SER B 1 83 ? 112.792 -44.404 45.536 0.50 11.85 ? 85 SER B CB 1 ATOM 3977 C CB B SER B 1 83 ? 112.868 -44.527 45.444 0.50 11.44 ? 85 SER B CB 1 ATOM 3978 O OG A SER B 1 83 ? 111.561 -45.030 45.850 0.50 12.64 ? 85 SER B OG 1 ATOM 3979 O OG B SER B 1 83 ? 113.644 -45.632 45.007 0.50 11.28 ? 85 SER B OG 1 ATOM 3980 N N . LEU B 1 84 ? 111.703 -41.474 45.221 1.00 11.07 ? 86 LEU B N 1 ATOM 3981 C CA . LEU B 1 84 ? 110.642 -40.509 45.500 1.00 11.33 ? 86 LEU B CA 1 ATOM 3982 C C . LEU B 1 84 ? 110.086 -39.918 44.206 1.00 11.01 ? 86 LEU B C 1 ATOM 3983 O O . LEU B 1 84 ? 108.873 -39.804 44.032 1.00 10.61 ? 86 LEU B O 1 ATOM 3984 C CB . LEU B 1 84 ? 111.147 -39.400 46.423 1.00 10.52 ? 86 LEU B CB 1 ATOM 3985 C CG . LEU B 1 84 ? 111.351 -39.811 47.884 1.00 11.41 ? 86 LEU B CG 1 ATOM 3986 C CD1 . LEU B 1 84 ? 112.073 -38.710 48.645 1.00 11.19 ? 86 LEU B CD1 1 ATOM 3987 C CD2 . LEU B 1 84 ? 110.020 -40.138 48.546 1.00 11.10 ? 86 LEU B CD2 1 ATOM 3988 N N . PHE B 1 85 ? 110.983 -39.559 43.294 1.00 10.69 ? 87 PHE B N 1 ATOM 3989 C CA . PHE B 1 85 ? 110.578 -39.090 41.975 1.00 10.38 ? 87 PHE B CA 1 ATOM 3990 C C . PHE B 1 85 ? 109.767 -40.157 41.245 1.00 10.71 ? 87 PHE B C 1 ATOM 3991 O O . PHE B 1 85 ? 108.715 -39.870 40.678 1.00 10.72 ? 87 PHE B O 1 ATOM 3992 C CB . PHE B 1 85 ? 111.803 -38.693 41.149 1.00 9.45 ? 87 PHE B CB 1 ATOM 3993 C CG . PHE B 1 85 ? 111.530 -38.564 39.674 1.00 9.12 ? 87 PHE B CG 1 ATOM 3994 C CD1 . PHE B 1 85 ? 110.913 -37.434 39.166 1.00 9.23 ? 87 PHE B CD1 1 ATOM 3995 C CD2 . PHE B 1 85 ? 111.941 -39.550 38.791 1.00 9.46 ? 87 PHE B CD2 1 ATOM 3996 C CE1 . PHE B 1 85 ? 110.687 -37.301 37.807 1.00 9.52 ? 87 PHE B CE1 1 ATOM 3997 C CE2 . PHE B 1 85 ? 111.701 -39.433 37.431 1.00 9.26 ? 87 PHE B CE2 1 ATOM 3998 C CZ . PHE B 1 85 ? 111.084 -38.302 36.937 1.00 9.27 ? 87 PHE B CZ 1 ATOM 3999 N N . ALA B 1 86 ? 110.251 -41.392 41.275 1.00 10.83 ? 88 ALA B N 1 ATOM 4000 C CA . ALA B 1 86 ? 109.586 -42.476 40.563 1.00 11.72 ? 88 ALA B CA 1 ATOM 4001 C C . ALA B 1 86 ? 108.139 -42.640 41.016 1.00 12.12 ? 88 ALA B C 1 ATOM 4002 O O . ALA B 1 86 ? 107.253 -42.885 40.204 1.00 11.83 ? 88 ALA B O 1 ATOM 4003 C CB . ALA B 1 86 ? 110.355 -43.777 40.734 1.00 12.31 ? 88 ALA B CB 1 ATOM 4004 N N . ASN B 1 87 ? 107.901 -42.479 42.314 1.00 12.73 ? 89 ASN B N 1 ATOM 4005 C CA . ASN B 1 87 ? 106.602 -42.799 42.887 1.00 14.33 ? 89 ASN B CA 1 ATOM 4006 C C . ASN B 1 87 ? 105.616 -41.630 42.893 1.00 13.34 ? 89 ASN B C 1 ATOM 4007 O O . ASN B 1 87 ? 104.409 -41.829 43.017 1.00 14.17 ? 89 ASN B O 1 ATOM 4008 C CB . ASN B 1 87 ? 106.774 -43.382 44.288 1.00 15.52 ? 89 ASN B CB 1 ATOM 4009 C CG . ASN B 1 87 ? 107.375 -44.773 44.260 1.00 17.89 ? 89 ASN B CG 1 ATOM 4010 O OD1 . ASN B 1 87 ? 106.879 -45.659 43.561 1.00 20.71 ? 89 ASN B OD1 1 ATOM 4011 N ND2 . ASN B 1 87 ? 108.488 -44.954 44.960 1.00 17.96 ? 89 ASN B ND2 1 ATOM 4012 N N . GLY B 1 88 ? 106.126 -40.421 42.681 1.00 12.39 ? 90 GLY B N 1 ATOM 4013 C CA . GLY B 1 88 ? 105.271 -39.239 42.564 1.00 11.84 ? 90 GLY B CA 1 ATOM 4014 C C . GLY B 1 88 ? 104.984 -38.607 43.912 1.00 11.91 ? 90 GLY B C 1 ATOM 4015 O O . GLY B 1 88 ? 105.045 -39.273 44.946 1.00 11.17 ? 90 GLY B O 1 ATOM 4016 N N . GLN B 1 89 ? 104.668 -37.315 43.907 1.00 11.46 ? 91 GLN B N 1 ATOM 4017 C CA . GLN B 1 89 ? 104.487 -36.589 45.159 1.00 11.60 ? 91 GLN B CA 1 ATOM 4018 C C . GLN B 1 89 ? 103.216 -36.998 45.910 1.00 11.84 ? 91 GLN B C 1 ATOM 4019 O O . GLN B 1 89 ? 103.196 -37.018 47.141 1.00 12.04 ? 91 GLN B O 1 ATOM 4020 C CB . GLN B 1 89 ? 104.524 -35.077 44.932 1.00 11.67 ? 91 GLN B CB 1 ATOM 4021 C CG . GLN B 1 89 ? 104.610 -34.270 46.218 1.00 12.44 ? 91 GLN B CG 1 ATOM 4022 C CD . GLN B 1 89 ? 104.442 -32.783 45.988 1.00 12.80 ? 91 GLN B CD 1 ATOM 4023 O OE1 . GLN B 1 89 ? 103.469 -32.180 46.443 1.00 13.80 ? 91 GLN B OE1 1 ATOM 4024 N NE2 . GLN B 1 89 ? 105.400 -32.176 45.291 1.00 12.33 ? 91 GLN B NE2 1 ATOM 4025 N N . ALA B 1 90 ? 102.165 -37.350 45.177 1.00 12.06 ? 92 ALA B N 1 ATOM 4026 C CA . ALA B 1 90 ? 100.920 -37.760 45.821 1.00 13.17 ? 92 ALA B CA 1 ATOM 4027 C C . ALA B 1 90 ? 101.150 -38.925 46.787 1.00 13.90 ? 92 ALA B C 1 ATOM 4028 O O . ALA B 1 90 ? 100.639 -38.922 47.907 1.00 13.67 ? 92 ALA B O 1 ATOM 4029 C CB . ALA B 1 90 ? 99.862 -38.115 44.787 1.00 12.88 ? 92 ALA B CB 1 ATOM 4030 N N . LYS B 1 91 ? 101.960 -39.893 46.367 1.00 15.12 ? 93 LYS B N 1 ATOM 4031 C CA . LYS B 1 91 ? 102.287 -41.032 47.218 1.00 16.12 ? 93 LYS B CA 1 ATOM 4032 C C . LYS B 1 91 ? 103.187 -40.638 48.383 1.00 15.84 ? 93 LYS B C 1 ATOM 4033 O O . LYS B 1 91 ? 103.246 -41.333 49.397 1.00 14.99 ? 93 LYS B O 1 ATOM 4034 C CB . LYS B 1 91 ? 102.934 -42.151 46.401 1.00 18.79 ? 93 LYS B CB 1 ATOM 4035 C CG . LYS B 1 91 ? 102.020 -43.348 46.191 1.00 21.01 ? 93 LYS B CG 1 ATOM 4036 C CD . LYS B 1 91 ? 102.134 -43.903 44.783 1.00 25.87 ? 93 LYS B CD 1 ATOM 4037 C CE . LYS B 1 91 ? 100.849 -44.602 44.368 1.00 28.18 ? 93 LYS B CE 1 ATOM 4038 N NZ . LYS B 1 91 ? 100.754 -44.754 42.888 1.00 32.19 ? 93 LYS B NZ 1 ATOM 4039 N N . ASP B 1 92 ? 103.877 -39.513 48.238 1.00 14.64 ? 94 ASP B N 1 ATOM 4040 C CA . ASP B 1 92 ? 104.796 -39.050 49.268 1.00 14.75 ? 94 ASP B CA 1 ATOM 4041 C C . ASP B 1 92 ? 104.107 -38.165 50.309 1.00 14.87 ? 94 ASP B C 1 ATOM 4042 O O . ASP B 1 92 ? 104.718 -37.777 51.300 1.00 14.89 ? 94 ASP B O 1 ATOM 4043 C CB . ASP B 1 92 ? 105.963 -38.296 48.625 1.00 15.58 ? 94 ASP B CB 1 ATOM 4044 C CG . ASP B 1 92 ? 107.152 -38.166 49.548 1.00 15.92 ? 94 ASP B CG 1 ATOM 4045 O OD1 . ASP B 1 92 ? 107.308 -39.027 50.443 1.00 15.57 ? 94 ASP B OD1 1 ATOM 4046 O OD2 . ASP B 1 92 ? 107.944 -37.214 49.359 1.00 15.30 ? 94 ASP B OD2 1 ATOM 4047 N N . ALA B 1 93 ? 102.837 -37.844 50.079 1.00 14.94 ? 95 ALA B N 1 ATOM 4048 C CA . ALA B 1 93 ? 102.146 -36.840 50.884 1.00 16.39 ? 95 ALA B CA 1 ATOM 4049 C C . ALA B 1 93 ? 102.068 -37.231 52.361 1.00 16.54 ? 95 ALA B C 1 ATOM 4050 O O . ALA B 1 93 ? 102.121 -36.374 53.242 1.00 15.37 ? 95 ALA B O 1 ATOM 4051 C CB . ALA B 1 93 ? 100.757 -36.572 50.326 1.00 17.31 ? 95 ALA B CB 1 ATOM 4052 N N . THR B 1 94 ? 101.964 -38.527 52.632 1.00 18.89 ? 96 THR B N 1 ATOM 4053 C CA . THR B 1 94 ? 101.878 -39.000 54.013 1.00 18.82 ? 96 THR B CA 1 ATOM 4054 C C . THR B 1 94 ? 103.154 -38.697 54.793 1.00 18.15 ? 96 THR B C 1 ATOM 4055 O O . THR B 1 94 ? 103.119 -38.548 56.014 1.00 19.36 ? 96 THR B O 1 ATOM 4056 C CB . THR B 1 94 ? 101.579 -40.507 54.084 1.00 21.15 ? 96 THR B CB 1 ATOM 4057 O OG1 . THR B 1 94 ? 102.463 -41.209 53.203 1.00 23.26 ? 96 THR B OG1 1 ATOM 4058 C CG2 . THR B 1 94 ? 100.138 -40.784 53.678 1.00 21.37 ? 96 THR B CG2 1 ATOM 4059 N N . SER B 1 95 ? 104.273 -38.579 54.083 1.00 17.59 ? 97 SER B N 1 ATOM 4060 C CA . SER B 1 95 ? 105.543 -38.214 54.708 1.00 17.44 ? 97 SER B CA 1 ATOM 4061 C C . SER B 1 95 ? 105.457 -36.842 55.361 1.00 17.60 ? 97 SER B C 1 ATOM 4062 O O . SER B 1 95 ? 106.212 -36.533 56.281 1.00 19.09 ? 97 SER B O 1 ATOM 4063 C CB . SER B 1 95 ? 106.678 -38.220 53.678 1.00 17.07 ? 97 SER B CB 1 ATOM 4064 O OG . SER B 1 95 ? 106.794 -39.483 53.053 1.00 16.30 ? 97 SER B OG 1 ATOM 4065 N N . PHE B 1 96 ? 104.547 -36.012 54.862 1.00 16.82 ? 98 PHE B N 1 ATOM 4066 C CA . PHE B 1 96 ? 104.426 -34.642 55.337 1.00 17.19 ? 98 PHE B CA 1 ATOM 4067 C C . PHE B 1 96 ? 103.175 -34.478 56.194 1.00 18.53 ? 98 PHE B C 1 ATOM 4068 O O . PHE B 1 96 ? 102.746 -33.361 56.486 1.00 18.51 ? 98 PHE B O 1 ATOM 4069 C CB . PHE B 1 96 ? 104.408 -33.669 54.156 1.00 17.00 ? 98 PHE B CB 1 ATOM 4070 C CG . PHE B 1 96 ? 105.460 -33.957 53.122 1.00 16.45 ? 98 PHE B CG 1 ATOM 4071 C CD1 . PHE B 1 96 ? 106.754 -34.279 53.501 1.00 16.64 ? 98 PHE B CD1 1 ATOM 4072 C CD2 . PHE B 1 96 ? 105.158 -33.902 51.770 1.00 16.80 ? 98 PHE B CD2 1 ATOM 4073 C CE1 . PHE B 1 96 ? 107.726 -34.545 52.555 1.00 17.78 ? 98 PHE B CE1 1 ATOM 4074 C CE2 . PHE B 1 96 ? 106.126 -34.166 50.817 1.00 17.39 ? 98 PHE B CE2 1 ATOM 4075 C CZ . PHE B 1 96 ? 107.412 -34.487 51.210 1.00 16.60 ? 98 PHE B CZ 1 ATOM 4076 N N . LYS B 1 97 ? 102.616 -35.604 56.625 1.00 19.81 ? 99 LYS B N 1 ATOM 4077 C CA . LYS B 1 97 ? 101.412 -35.600 57.442 1.00 19.50 ? 99 LYS B CA 1 ATOM 4078 C C . LYS B 1 97 ? 100.352 -34.694 56.832 1.00 19.59 ? 99 LYS B C 1 ATOM 4079 O O . LYS B 1 97 ? 99.809 -33.810 57.495 1.00 19.95 ? 99 LYS B O 1 ATOM 4080 C CB . LYS B 1 97 ? 101.738 -35.176 58.873 1.00 20.83 ? 99 LYS B CB 1 ATOM 4081 C CG . LYS B 1 97 ? 102.776 -36.066 59.537 1.00 21.02 ? 99 LYS B CG 1 ATOM 4082 C CD . LYS B 1 97 ? 103.036 -35.646 60.972 1.00 23.90 ? 99 LYS B CD 1 ATOM 4083 C CE . LYS B 1 97 ? 104.015 -36.595 61.644 1.00 26.42 ? 99 LYS B CE 1 ATOM 4084 N NZ . LYS B 1 97 ? 104.491 -36.061 62.949 1.00 31.08 ? 99 LYS B NZ 1 ATOM 4085 N N . GLU B 1 98 ? 100.084 -34.909 55.551 1.00 19.32 ? 100 GLU B N 1 ATOM 4086 C CA . GLU B 1 98 ? 99.016 -34.200 54.869 1.00 20.14 ? 100 GLU B CA 1 ATOM 4087 C C . GLU B 1 98 ? 98.224 -35.157 53.987 1.00 19.83 ? 100 GLU B C 1 ATOM 4088 O O . GLU B 1 98 ? 98.731 -36.200 53.563 1.00 20.84 ? 100 GLU B O 1 ATOM 4089 C CB . GLU B 1 98 ? 99.576 -33.037 54.045 1.00 20.73 ? 100 GLU B CB 1 ATOM 4090 C CG . GLU B 1 98 ? 99.875 -33.375 52.594 1.00 19.56 ? 100 GLU B CG 1 ATOM 4091 C CD . GLU B 1 98 ? 100.634 -32.268 51.883 1.00 19.02 ? 100 GLU B CD 1 ATOM 4092 O OE1 . GLU B 1 98 ? 101.576 -31.708 52.483 1.00 17.71 ? 100 GLU B OE1 1 ATOM 4093 O OE2 . GLU B 1 98 ? 100.292 -31.959 50.721 1.00 18.54 ? 100 GLU B OE2 1 ATOM 4094 N N . SER B 1 99 ? 96.968 -34.806 53.742 1.00 20.04 ? 101 SER B N 1 ATOM 4095 C CA . SER B 1 99 ? 96.091 -35.606 52.902 1.00 21.42 ? 101 SER B CA 1 ATOM 4096 C C . SER B 1 99 ? 96.013 -34.981 51.515 1.00 21.12 ? 101 SER B C 1 ATOM 4097 O O . SER B 1 99 ? 96.153 -33.766 51.370 1.00 20.28 ? 101 SER B O 1 ATOM 4098 C CB . SER B 1 99 ? 94.697 -35.677 53.533 1.00 21.79 ? 101 SER B CB 1 ATOM 4099 O OG . SER B 1 99 ? 93.717 -36.046 52.582 1.00 22.98 ? 101 SER B OG 1 ATOM 4100 N N . THR B 1 100 ? 95.807 -35.809 50.495 1.00 20.30 ? 102 THR B N 1 ATOM 4101 C CA . THR B 1 100 ? 95.665 -35.308 49.131 1.00 20.79 ? 102 THR B CA 1 ATOM 4102 C C . THR B 1 100 ? 94.237 -34.861 48.822 1.00 22.61 ? 102 THR B C 1 ATOM 4103 O O . THR B 1 100 ? 93.941 -34.439 47.704 1.00 21.52 ? 102 THR B O 1 ATOM 4104 C CB . THR B 1 100 ? 96.101 -36.352 48.084 1.00 21.27 ? 102 THR B CB 1 ATOM 4105 O OG1 . THR B 1 100 ? 95.251 -37.502 48.168 1.00 22.58 ? 102 THR B OG1 1 ATOM 4106 C CG2 . THR B 1 100 ? 97.544 -36.771 48.313 1.00 21.09 ? 102 THR B CG2 1 ATOM 4107 N N . SER B 1 101 ? 93.355 -34.950 49.814 1.00 24.98 ? 103 SER B N 1 ATOM 4108 C CA . SER B 1 101 ? 91.936 -34.674 49.595 1.00 24.51 ? 103 SER B CA 1 ATOM 4109 C C . SER B 1 101 ? 91.649 -33.198 49.310 1.00 24.89 ? 103 SER B C 1 ATOM 4110 O O . SER B 1 101 ? 90.616 -32.863 48.734 1.00 27.77 ? 103 SER B O 1 ATOM 4111 C CB . SER B 1 101 ? 91.094 -35.171 50.774 1.00 25.05 ? 103 SER B CB 1 ATOM 4112 O OG . SER B 1 101 ? 91.525 -34.584 51.988 1.00 26.76 ? 103 SER B OG 1 ATOM 4113 N N . SER B 1 102 ? 92.573 -32.322 49.690 1.00 24.17 ? 104 SER B N 1 ATOM 4114 C CA . SER B 1 102 ? 92.431 -30.897 49.407 1.00 24.50 ? 104 SER B CA 1 ATOM 4115 C C . SER B 1 102 ? 93.288 -30.459 48.218 1.00 22.27 ? 104 SER B C 1 ATOM 4116 O O . SER B 1 102 ? 93.352 -29.274 47.887 1.00 20.83 ? 104 SER B O 1 ATOM 4117 C CB . SER B 1 102 ? 92.786 -30.066 50.643 1.00 28.47 ? 104 SER B CB 1 ATOM 4118 O OG . SER B 1 102 ? 94.175 -30.136 50.927 1.00 29.86 ? 104 SER B OG 1 ATOM 4119 N N . TRP B 1 103 ? 93.953 -31.420 47.585 1.00 19.02 ? 105 TRP B N 1 ATOM 4120 C CA . TRP B 1 103 ? 94.860 -31.123 46.479 1.00 17.03 ? 105 TRP B CA 1 ATOM 4121 C C . TRP B 1 103 ? 94.083 -30.686 45.246 1.00 16.10 ? 105 TRP B C 1 ATOM 4122 O O . TRP B 1 103 ? 92.931 -31.073 45.063 1.00 16.08 ? 105 TRP B O 1 ATOM 4123 C CB . TRP B 1 103 ? 95.694 -32.360 46.140 1.00 15.88 ? 105 TRP B CB 1 ATOM 4124 C CG . TRP B 1 103 ? 96.884 -32.552 47.023 1.00 16.06 ? 105 TRP B CG 1 ATOM 4125 C CD1 . TRP B 1 103 ? 97.038 -32.111 48.306 1.00 15.16 ? 105 TRP B CD1 1 ATOM 4126 C CD2 . TRP B 1 103 ? 98.091 -33.245 46.689 1.00 14.94 ? 105 TRP B CD2 1 ATOM 4127 N NE1 . TRP B 1 103 ? 98.268 -32.487 48.791 1.00 14.80 ? 105 TRP B NE1 1 ATOM 4128 C CE2 . TRP B 1 103 ? 98.934 -33.185 47.818 1.00 14.93 ? 105 TRP B CE2 1 ATOM 4129 C CE3 . TRP B 1 103 ? 98.543 -33.908 45.543 1.00 14.13 ? 105 TRP B CE3 1 ATOM 4130 C CZ2 . TRP B 1 103 ? 100.208 -33.756 47.832 1.00 14.49 ? 105 TRP B CZ2 1 ATOM 4131 C CZ3 . TRP B 1 103 ? 99.806 -34.478 45.560 1.00 13.87 ? 105 TRP B CZ3 1 ATOM 4132 C CH2 . TRP B 1 103 ? 100.623 -34.397 46.696 1.00 14.17 ? 105 TRP B CH2 1 ATOM 4133 N N . VAL B 1 104 ? 94.724 -29.896 44.389 1.00 14.81 ? 106 VAL B N 1 ATOM 4134 C CA . VAL B 1 104 ? 94.308 -29.815 42.998 1.00 15.18 ? 106 VAL B CA 1 ATOM 4135 C C . VAL B 1 104 ? 94.143 -31.235 42.470 1.00 15.13 ? 106 VAL B C 1 ATOM 4136 O O . VAL B 1 104 ? 95.083 -32.028 42.516 1.00 15.38 ? 106 VAL B O 1 ATOM 4137 C CB . VAL B 1 104 ? 95.355 -29.084 42.138 1.00 14.76 ? 106 VAL B CB 1 ATOM 4138 C CG1 . VAL B 1 104 ? 94.837 -28.895 40.720 1.00 15.05 ? 106 VAL B CG1 1 ATOM 4139 C CG2 . VAL B 1 104 ? 95.729 -27.752 42.768 1.00 14.60 ? 106 VAL B CG2 1 ATOM 4140 N N . PRO B 1 105 ? 92.932 -31.574 42.001 1.00 15.08 ? 107 PRO B N 1 ATOM 4141 C CA . PRO B 1 105 ? 92.625 -32.947 41.603 1.00 14.91 ? 107 PRO B CA 1 ATOM 4142 C C . PRO B 1 105 ? 93.694 -33.536 40.684 1.00 14.78 ? 107 PRO B C 1 ATOM 4143 O O . PRO B 1 105 ? 94.091 -34.687 40.853 1.00 14.83 ? 107 PRO B O 1 ATOM 4144 C CB . PRO B 1 105 ? 91.297 -32.803 40.856 1.00 15.38 ? 107 PRO B CB 1 ATOM 4145 C CG . PRO B 1 105 ? 90.653 -31.611 41.484 1.00 15.29 ? 107 PRO B CG 1 ATOM 4146 C CD . PRO B 1 105 ? 91.776 -30.673 41.837 1.00 15.04 ? 107 PRO B CD 1 ATOM 4147 N N . GLN B 1 106 ? 94.190 -32.733 39.749 1.00 15.49 ? 108 GLN B N 1 ATOM 4148 C CA . GLN B 1 106 ? 95.168 -33.209 38.775 1.00 15.25 ? 108 GLN B CA 1 ATOM 4149 C C . GLN B 1 106 ? 96.503 -33.614 39.406 1.00 14.51 ? 108 GLN B C 1 ATOM 4150 O O . GLN B 1 106 ? 97.242 -34.413 38.831 1.00 13.69 ? 108 GLN B O 1 ATOM 4151 C CB . GLN B 1 106 ? 95.389 -32.170 37.674 1.00 15.37 ? 108 GLN B CB 1 ATOM 4152 C CG . GLN B 1 106 ? 94.239 -32.063 36.682 1.00 16.68 ? 108 GLN B CG 1 ATOM 4153 C CD . GLN B 1 106 ? 93.074 -31.247 37.213 1.00 17.85 ? 108 GLN B CD 1 ATOM 4154 O OE1 . GLN B 1 106 ? 93.213 -30.493 38.178 1.00 16.95 ? 108 GLN B OE1 1 ATOM 4155 N NE2 . GLN B 1 106 ? 91.910 -31.408 36.592 1.00 19.81 ? 108 GLN B NE2 1 ATOM 4156 N N . PHE B 1 107 ? 96.802 -33.074 40.586 1.00 14.17 ? 109 PHE B N 1 ATOM 4157 C CA . PHE B 1 107 ? 98.035 -33.416 41.299 1.00 14.02 ? 109 PHE B CA 1 ATOM 4158 C C . PHE B 1 107 ? 97.894 -34.732 42.066 1.00 14.96 ? 109 PHE B C 1 ATOM 4159 O O . PHE B 1 107 ? 98.888 -35.389 42.387 1.00 13.16 ? 109 PHE B O 1 ATOM 4160 C CB . PHE B 1 107 ? 98.432 -32.300 42.275 1.00 14.17 ? 109 PHE B CB 1 ATOM 4161 C CG . PHE B 1 107 ? 99.036 -31.090 41.612 1.00 14.45 ? 109 PHE B CG 1 ATOM 4162 C CD1 . PHE B 1 107 ? 99.866 -31.225 40.509 1.00 14.62 ? 109 PHE B CD1 1 ATOM 4163 C CD2 . PHE B 1 107 ? 98.818 -29.823 42.129 1.00 14.90 ? 109 PHE B CD2 1 ATOM 4164 C CE1 . PHE B 1 107 ? 100.421 -30.111 39.900 1.00 15.57 ? 109 PHE B CE1 1 ATOM 4165 C CE2 . PHE B 1 107 ? 99.370 -28.706 41.527 1.00 15.12 ? 109 PHE B CE2 1 ATOM 4166 C CZ . PHE B 1 107 ? 100.171 -28.851 40.409 1.00 14.67 ? 109 PHE B CZ 1 ATOM 4167 N N . ALA B 1 108 ? 96.655 -35.090 42.388 1.00 14.93 ? 110 ALA B N 1 ATOM 4168 C CA . ALA B 1 108 ? 96.384 -36.215 43.272 1.00 15.86 ? 110 ALA B CA 1 ATOM 4169 C C . ALA B 1 108 ? 96.358 -37.520 42.484 1.00 17.06 ? 110 ALA B C 1 ATOM 4170 O O . ALA B 1 108 ? 95.319 -38.167 42.367 1.00 17.13 ? 110 ALA B O 1 ATOM 4171 C CB . ALA B 1 108 ? 95.067 -36.004 44.005 1.00 15.64 ? 110 ALA B CB 1 ATOM 4172 N N . GLY B 1 109 ? 97.514 -37.897 41.950 1.00 16.12 ? 111 GLY B N 1 ATOM 4173 C CA . GLY B 1 109 ? 97.608 -38.971 40.970 1.00 16.03 ? 111 GLY B CA 1 ATOM 4174 C C . GLY B 1 109 ? 98.921 -38.850 40.221 1.00 15.26 ? 111 GLY B C 1 ATOM 4175 O O . GLY B 1 109 ? 99.794 -38.082 40.619 1.00 15.86 ? 111 GLY B O 1 ATOM 4176 N N . THR B 1 110 ? 99.055 -39.576 39.118 1.00 14.39 ? 112 THR B N 1 ATOM 4177 C CA . THR B 1 110 ? 100.226 -39.433 38.264 1.00 13.60 ? 112 THR B CA 1 ATOM 4178 C C . THR B 1 110 ? 99.834 -39.265 36.797 1.00 12.29 ? 112 THR B C 1 ATOM 4179 O O . THR B 1 110 ? 100.540 -39.714 35.896 1.00 11.60 ? 112 THR B O 1 ATOM 4180 C CB . THR B 1 110 ? 101.213 -40.607 38.439 1.00 13.93 ? 112 THR B CB 1 ATOM 4181 O OG1 . THR B 1 110 ? 100.522 -41.849 38.258 1.00 14.96 ? 112 THR B OG1 1 ATOM 4182 C CG2 . THR B 1 110 ? 101.826 -40.580 39.833 1.00 14.47 ? 112 THR B CG2 1 ATOM 4183 N N . GLY B 1 111 ? 98.722 -38.572 36.563 1.00 11.82 ? 113 GLY B N 1 ATOM 4184 C CA . GLY B 1 111 ? 98.290 -38.265 35.205 1.00 11.27 ? 113 GLY B CA 1 ATOM 4185 C C . GLY B 1 111 ? 99.142 -37.200 34.540 1.00 10.63 ? 113 GLY B C 1 ATOM 4186 O O . GLY B 1 111 ? 99.236 -37.139 33.312 1.00 10.33 ? 113 GLY B O 1 ATOM 4187 N N . ILE B 1 112 ? 99.768 -36.353 35.348 1.00 10.14 ? 114 ILE B N 1 ATOM 4188 C CA . ILE B 1 112 ? 100.589 -35.274 34.803 1.00 9.71 ? 114 ILE B CA 1 ATOM 4189 C C . ILE B 1 112 ? 101.936 -35.811 34.335 1.00 9.24 ? 114 ILE B C 1 ATOM 4190 O O . ILE B 1 112 ? 102.656 -36.451 35.106 1.00 8.85 ? 114 ILE B O 1 ATOM 4191 C CB . ILE B 1 112 ? 100.809 -34.151 35.831 1.00 9.62 ? 114 ILE B CB 1 ATOM 4192 C CG1 . ILE B 1 112 ? 99.524 -33.342 36.009 1.00 10.14 ? 114 ILE B CG1 1 ATOM 4193 C CG2 . ILE B 1 112 ? 101.950 -33.241 35.392 1.00 9.45 ? 114 ILE B CG2 1 ATOM 4194 C CD1 . ILE B 1 112 ? 99.473 -32.563 37.307 1.00 11.16 ? 114 ILE B CD1 1 ATOM 4195 N N . HIS B 1 113 ? 102.264 -35.558 33.070 1.00 8.83 ? 115 HIS B N 1 ATOM 4196 C CA . HIS B 1 113 ? 103.484 -36.087 32.470 1.00 8.72 ? 115 HIS B CA 1 ATOM 4197 C C . HIS B 1 113 ? 104.635 -35.092 32.502 1.00 8.45 ? 115 HIS B C 1 ATOM 4198 O O . HIS B 1 113 ? 105.795 -35.475 32.379 1.00 8.46 ? 115 HIS B O 1 ATOM 4199 C CB . HIS B 1 113 ? 103.229 -36.548 31.032 1.00 9.18 ? 115 HIS B CB 1 ATOM 4200 C CG . HIS B 1 113 ? 102.383 -37.778 30.940 1.00 9.87 ? 115 HIS B CG 1 ATOM 4201 N ND1 . HIS B 1 113 ? 101.695 -38.129 29.799 1.00 10.67 ? 115 HIS B ND1 1 ATOM 4202 C CD2 . HIS B 1 113 ? 102.108 -38.737 31.855 1.00 10.05 ? 115 HIS B CD2 1 ATOM 4203 C CE1 . HIS B 1 113 ? 101.032 -39.251 30.014 1.00 10.84 ? 115 HIS B CE1 1 ATOM 4204 N NE2 . HIS B 1 113 ? 101.263 -39.639 31.256 1.00 10.30 ? 115 HIS B NE2 1 ATOM 4205 N N . GLY B 1 114 ? 104.320 -33.816 32.684 1.00 7.94 ? 116 GLY B N 1 ATOM 4206 C CA . GLY B 1 114 ? 105.369 -32.814 32.776 1.00 8.33 ? 116 GLY B CA 1 ATOM 4207 C C . GLY B 1 114 ? 104.861 -31.402 32.971 1.00 8.19 ? 116 GLY B C 1 ATOM 4208 O O . GLY B 1 114 ? 103.659 -31.165 33.096 1.00 7.90 ? 116 GLY B O 1 ATOM 4209 N N . VAL B 1 115 ? 105.795 -30.463 33.022 1.00 8.24 ? 117 VAL B N 1 ATOM 4210 C CA . VAL B 1 115 ? 105.450 -29.066 33.184 1.00 8.19 ? 117 VAL B CA 1 ATOM 4211 C C . VAL B 1 115 ? 106.326 -28.225 32.279 1.00 8.41 ? 117 VAL B C 1 ATOM 4212 O O . VAL B 1 115 ? 107.531 -28.458 32.169 1.00 7.86 ? 117 VAL B O 1 ATOM 4213 C CB . VAL B 1 115 ? 105.616 -28.604 34.647 1.00 8.26 ? 117 VAL B CB 1 ATOM 4214 C CG1 . VAL B 1 115 ? 107.026 -28.888 35.143 1.00 7.92 ? 117 VAL B CG1 1 ATOM 4215 C CG2 . VAL B 1 115 ? 105.272 -27.124 34.786 1.00 8.12 ? 117 VAL B CG2 1 ATOM 4216 N N . ILE B 1 116 ? 105.699 -27.294 31.573 1.00 8.44 ? 118 ILE B N 1 ATOM 4217 C CA . ILE B 1 116 ? 106.438 -26.261 30.878 1.00 9.09 ? 118 ILE B CA 1 ATOM 4218 C C . ILE B 1 116 ? 106.398 -25.004 31.730 1.00 9.22 ? 118 ILE B C 1 ATOM 4219 O O . ILE B 1 116 ? 105.331 -24.596 32.181 1.00 9.52 ? 118 ILE B O 1 ATOM 4220 C CB . ILE B 1 116 ? 105.823 -25.963 29.499 1.00 9.07 ? 118 ILE B CB 1 ATOM 4221 C CG1 . ILE B 1 116 ? 105.805 -27.233 28.649 1.00 9.29 ? 118 ILE B CG1 1 ATOM 4222 C CG2 . ILE B 1 116 ? 106.604 -24.861 28.802 1.00 9.23 ? 118 ILE B CG2 1 ATOM 4223 C CD1 . ILE B 1 116 ? 105.095 -27.072 27.321 1.00 9.23 ? 118 ILE B CD1 1 ATOM 4224 N N . ILE B 1 117 ? 107.569 -24.456 32.036 1.00 9.50 ? 119 ILE B N 1 ATOM 4225 C CA . ILE B 1 117 ? 107.636 -23.178 32.731 1.00 9.83 ? 119 ILE B CA 1 ATOM 4226 C C . ILE B 1 117 ? 107.919 -22.072 31.727 1.00 10.52 ? 119 ILE B C 1 ATOM 4227 O O . ILE B 1 117 ? 108.961 -22.078 31.069 1.00 10.45 ? 119 ILE B O 1 ATOM 4228 C CB . ILE B 1 117 ? 108.738 -23.169 33.803 1.00 10.43 ? 119 ILE B CB 1 ATOM 4229 C CG1 . ILE B 1 117 ? 108.558 -24.342 34.769 1.00 10.82 ? 119 ILE B CG1 1 ATOM 4230 C CG2 . ILE B 1 117 ? 108.730 -21.848 34.560 1.00 11.09 ? 119 ILE B CG2 1 ATOM 4231 C CD1 . ILE B 1 117 ? 109.783 -24.624 35.614 1.00 12.17 ? 119 ILE B CD1 1 ATOM 4232 N N . LEU B 1 118 ? 106.971 -21.151 31.583 1.00 10.69 ? 120 LEU B N 1 ATOM 4233 C CA . LEU B 1 118 ? 107.171 -19.967 30.755 1.00 11.91 ? 120 LEU B CA 1 ATOM 4234 C C . LEU B 1 118 ? 107.329 -18.740 31.638 1.00 11.93 ? 120 LEU B C 1 ATOM 4235 O O . LEU B 1 118 ? 106.596 -18.570 32.611 1.00 12.77 ? 120 LEU B O 1 ATOM 4236 C CB . LEU B 1 118 ? 105.995 -19.773 29.794 1.00 12.00 ? 120 LEU B CB 1 ATOM 4237 C CG . LEU B 1 118 ? 105.719 -20.908 28.807 1.00 13.04 ? 120 LEU B CG 1 ATOM 4238 C CD1 . LEU B 1 118 ? 104.443 -20.637 28.029 1.00 14.26 ? 120 LEU B CD1 1 ATOM 4239 C CD2 . LEU B 1 118 ? 106.886 -21.080 27.850 1.00 14.26 ? 120 LEU B CD2 1 ATOM 4240 N N . ALA B 1 119 ? 108.327 -17.919 31.330 1.00 12.43 ? 121 ALA B N 1 ATOM 4241 C CA . ALA B 1 119 ? 108.586 -16.704 32.090 1.00 12.72 ? 121 ALA B CA 1 ATOM 4242 C C . ALA B 1 119 ? 108.827 -15.535 31.142 1.00 13.16 ? 121 ALA B C 1 ATOM 4243 O O . ALA B 1 119 ? 109.525 -15.670 30.141 1.00 13.03 ? 121 ALA B O 1 ATOM 4244 C CB . ALA B 1 119 ? 109.784 -16.897 33.007 1.00 13.10 ? 121 ALA B CB 1 ATOM 4245 N N . SER B 1 120 ? 108.210 -14.399 31.442 1.00 14.04 ? 122 SER B N 1 ATOM 4246 C CA . SER B 1 120 ? 108.366 -13.206 30.623 1.00 14.24 ? 122 SER B CA 1 ATOM 4247 C C . SER B 1 120 ? 107.957 -11.998 31.444 1.00 14.95 ? 122 SER B C 1 ATOM 4248 O O . SER B 1 120 ? 107.352 -12.137 32.503 1.00 14.21 ? 122 SER B O 1 ATOM 4249 C CB . SER B 1 120 ? 107.491 -13.296 29.370 1.00 14.21 ? 122 SER B CB 1 ATOM 4250 O OG . SER B 1 120 ? 107.877 -12.325 28.412 1.00 15.85 ? 122 SER B OG 1 ATOM 4251 N N . ASP B 1 121 ? 108.281 -10.810 30.952 1.00 17.17 ? 123 ASP B N 1 ATOM 4252 C CA . ASP B 1 121 ? 107.959 -9.596 31.687 1.00 18.80 ? 123 ASP B CA 1 ATOM 4253 C C . ASP B 1 121 ? 106.519 -9.144 31.447 1.00 18.03 ? 123 ASP B C 1 ATOM 4254 O O . ASP B 1 121 ? 106.013 -8.279 32.155 1.00 19.28 ? 123 ASP B O 1 ATOM 4255 C CB . ASP B 1 121 ? 108.956 -8.481 31.364 1.00 20.95 ? 123 ASP B CB 1 ATOM 4256 C CG . ASP B 1 121 ? 110.301 -8.685 32.046 1.00 23.00 ? 123 ASP B CG 1 ATOM 4257 O OD1 . ASP B 1 121 ? 110.345 -9.327 33.119 1.00 22.13 ? 123 ASP B OD1 1 ATOM 4258 O OD2 . ASP B 1 121 ? 111.317 -8.198 31.510 1.00 27.61 ? 123 ASP B OD2 1 ATOM 4259 N N . THR B 1 122 ? 105.842 -9.772 30.490 1.00 17.33 ? 124 THR B N 1 ATOM 4260 C CA . THR B 1 122 ? 104.403 -9.562 30.324 1.00 17.58 ? 124 THR B CA 1 ATOM 4261 C C . THR B 1 122 ? 103.629 -10.869 30.188 1.00 18.06 ? 124 THR B C 1 ATOM 4262 O O . THR B 1 122 ? 104.141 -11.858 29.664 1.00 16.79 ? 124 THR B O 1 ATOM 4263 C CB . THR B 1 122 ? 104.081 -8.658 29.116 1.00 18.95 ? 124 THR B CB 1 ATOM 4264 O OG1 . THR B 1 122 ? 104.194 -9.411 27.902 1.00 18.26 ? 124 THR B OG1 1 ATOM 4265 C CG2 . THR B 1 122 ? 105.032 -7.471 29.066 1.00 18.25 ? 124 THR B CG2 1 ATOM 4266 N N . THR B 1 123 ? 102.373 -10.851 30.616 1.00 17.35 ? 125 THR B N 1 ATOM 4267 C CA . THR B 1 123 ? 101.511 -12.015 30.475 1.00 17.64 ? 125 THR B CA 1 ATOM 4268 C C . THR B 1 123 ? 101.168 -12.275 29.008 1.00 17.80 ? 125 THR B C 1 ATOM 4269 O O . THR B 1 123 ? 100.969 -13.420 28.602 1.00 16.09 ? 125 THR B O 1 ATOM 4270 C CB . THR B 1 123 ? 100.219 -11.861 31.296 1.00 18.62 ? 125 THR B CB 1 ATOM 4271 O OG1 . THR B 1 123 ? 99.679 -10.550 31.100 1.00 23.13 ? 125 THR B OG1 1 ATOM 4272 C CG2 . THR B 1 123 ? 100.511 -12.055 32.778 1.00 18.63 ? 125 THR B CG2 1 ATOM 4273 N N . ASP B 1 124 ? 101.111 -11.208 28.217 1.00 17.50 ? 126 ASP B N 1 ATOM 4274 C CA . ASP B 1 124 ? 100.788 -11.329 26.797 1.00 18.05 ? 126 ASP B CA 1 ATOM 4275 C C . ASP B 1 124 ? 101.802 -12.193 26.050 1.00 16.72 ? 126 ASP B C 1 ATOM 4276 O O . ASP B 1 124 ? 101.431 -13.041 25.240 1.00 16.77 ? 126 ASP B O 1 ATOM 4277 C CB . ASP B 1 124 ? 100.688 -9.950 26.145 1.00 20.26 ? 126 ASP B CB 1 ATOM 4278 C CG . ASP B 1 124 ? 99.336 -9.299 26.366 1.00 22.40 ? 126 ASP B CG 1 ATOM 4279 O OD1 . ASP B 1 124 ? 98.424 -9.984 26.873 1.00 22.91 ? 126 ASP B OD1 1 ATOM 4280 O OD2 . ASP B 1 124 ? 99.179 -8.108 26.017 1.00 25.41 ? 126 ASP B OD2 1 ATOM 4281 N N . LEU B 1 125 ? 103.083 -11.969 26.319 1.00 15.91 ? 127 LEU B N 1 ATOM 4282 C CA . LEU B 1 125 ? 104.131 -12.745 25.669 1.00 15.52 ? 127 LEU B CA 1 ATOM 4283 C C . LEU B 1 125 ? 104.036 -14.226 26.044 1.00 14.70 ? 127 LEU B C 1 ATOM 4284 O O . LEU B 1 125 ? 104.201 -15.101 25.193 1.00 14.25 ? 127 LEU B O 1 ATOM 4285 C CB . LEU B 1 125 ? 105.512 -12.178 26.001 1.00 15.91 ? 127 LEU B CB 1 ATOM 4286 C CG . LEU B 1 125 ? 105.828 -10.813 25.379 1.00 16.50 ? 127 LEU B CG 1 ATOM 4287 C CD1 . LEU B 1 125 ? 106.957 -10.109 26.117 1.00 16.88 ? 127 LEU B CD1 1 ATOM 4288 C CD2 . LEU B 1 125 ? 106.150 -10.951 23.899 1.00 16.41 ? 127 LEU B CD2 1 ATOM 4289 N N . ILE B 1 126 ? 103.727 -14.497 27.310 1.00 14.13 ? 128 ILE B N 1 ATOM 4290 C CA . ILE B 1 126 ? 103.498 -15.867 27.767 1.00 13.54 ? 128 ILE B CA 1 ATOM 4291 C C . ILE B 1 126 ? 102.305 -16.502 27.055 1.00 13.87 ? 128 ILE B C 1 ATOM 4292 O O . ILE B 1 126 ? 102.383 -17.639 26.595 1.00 12.56 ? 128 ILE B O 1 ATOM 4293 C CB . ILE B 1 126 ? 103.267 -15.926 29.292 1.00 13.77 ? 128 ILE B CB 1 ATOM 4294 C CG1 . ILE B 1 126 ? 104.559 -15.592 30.043 1.00 13.15 ? 128 ILE B CG1 1 ATOM 4295 C CG2 . ILE B 1 126 ? 102.746 -17.296 29.704 1.00 12.38 ? 128 ILE B CG2 1 ATOM 4296 C CD1 . ILE B 1 126 ? 104.418 -15.643 31.550 1.00 13.34 ? 128 ILE B CD1 1 ATOM 4297 N N . ASP B 1 127 ? 101.199 -15.764 26.976 1.00 15.36 ? 129 ASP B N 1 ATOM 4298 C CA . ASP B 1 127 ? 99.963 -16.290 26.403 1.00 15.91 ? 129 ASP B CA 1 ATOM 4299 C C . ASP B 1 127 ? 100.128 -16.624 24.920 1.00 14.75 ? 129 ASP B C 1 ATOM 4300 O O . ASP B 1 127 ? 99.595 -17.622 24.436 1.00 14.12 ? 129 ASP B O 1 ATOM 4301 C CB . ASP B 1 127 ? 98.810 -15.303 26.595 1.00 17.76 ? 129 ASP B CB 1 ATOM 4302 C CG . ASP B 1 127 ? 98.298 -15.270 28.025 1.00 20.45 ? 129 ASP B CG 1 ATOM 4303 O OD1 . ASP B 1 127 ? 98.726 -16.113 28.841 1.00 22.01 ? 129 ASP B OD1 1 ATOM 4304 O OD2 . ASP B 1 127 ? 97.457 -14.401 28.333 1.00 25.92 ? 129 ASP B OD2 1 ATOM 4305 N N . GLN B 1 128 ? 100.869 -15.789 24.201 1.00 14.36 ? 130 GLN B N 1 ATOM 4306 C CA . GLN B 1 128 ? 101.107 -16.037 22.788 1.00 14.61 ? 130 GLN B CA 1 ATOM 4307 C C . GLN B 1 128 ? 102.037 -17.234 22.597 1.00 15.29 ? 130 GLN B C 1 ATOM 4308 O O . GLN B 1 128 ? 101.897 -17.992 21.637 1.00 15.48 ? 130 GLN B O 1 ATOM 4309 C CB . GLN B 1 128 ? 101.690 -14.805 22.104 1.00 14.43 ? 130 GLN B CB 1 ATOM 4310 C CG . GLN B 1 128 ? 101.714 -14.911 20.589 1.00 14.73 ? 130 GLN B CG 1 ATOM 4311 C CD . GLN B 1 128 ? 100.320 -15.033 20.005 1.00 15.18 ? 130 GLN B CD 1 ATOM 4312 O OE1 . GLN B 1 128 ? 99.401 -14.321 20.418 1.00 13.41 ? 130 GLN B OE1 1 ATOM 4313 N NE2 . GLN B 1 128 ? 100.150 -15.948 19.050 1.00 13.67 ? 130 GLN B NE2 1 ATOM 4314 N N . GLN B 1 129 ? 102.977 -17.405 23.521 1.00 15.02 ? 131 GLN B N 1 ATOM 4315 C CA . GLN B 1 129 ? 103.877 -18.554 23.484 1.00 16.98 ? 131 GLN B CA 1 ATOM 4316 C C . GLN B 1 129 ? 103.127 -19.857 23.773 1.00 14.40 ? 131 GLN B C 1 ATOM 4317 O O . GLN B 1 129 ? 103.408 -20.890 23.168 1.00 14.31 ? 131 GLN B O 1 ATOM 4318 C CB . GLN B 1 129 ? 105.032 -18.367 24.473 1.00 20.41 ? 131 GLN B CB 1 ATOM 4319 C CG . GLN B 1 129 ? 106.168 -19.362 24.306 1.00 24.04 ? 131 GLN B CG 1 ATOM 4320 C CD . GLN B 1 129 ? 107.011 -19.085 23.075 1.00 26.99 ? 131 GLN B CD 1 ATOM 4321 O OE1 . GLN B 1 129 ? 107.676 -19.979 22.551 1.00 34.35 ? 131 GLN B OE1 1 ATOM 4322 N NE2 . GLN B 1 129 ? 106.973 -17.845 22.596 1.00 26.61 ? 131 GLN B NE2 1 ATOM 4323 N N . VAL B 1 130 ? 102.164 -19.802 24.687 1.00 12.78 ? 132 VAL B N 1 ATOM 4324 C CA . VAL B 1 130 ? 101.326 -20.961 24.973 1.00 12.26 ? 132 VAL B CA 1 ATOM 4325 C C . VAL B 1 130 ? 100.491 -21.339 23.756 1.00 11.69 ? 132 VAL B C 1 ATOM 4326 O O . VAL B 1 130 ? 100.380 -22.515 23.403 1.00 10.40 ? 132 VAL B O 1 ATOM 4327 C CB . VAL B 1 130 ? 100.378 -20.714 26.159 1.00 11.82 ? 132 VAL B CB 1 ATOM 4328 C CG1 . VAL B 1 130 ? 99.320 -21.804 26.216 1.00 11.66 ? 132 VAL B CG1 1 ATOM 4329 C CG2 . VAL B 1 130 ? 101.159 -20.665 27.465 1.00 11.73 ? 132 VAL B CG2 1 ATOM 4330 N N . ALA B 1 131 ? 99.910 -20.331 23.115 1.00 10.63 ? 133 ALA B N 1 ATOM 4331 C CA . ALA B 1 131 ? 99.148 -20.551 21.893 1.00 10.87 ? 133 ALA B CA 1 ATOM 4332 C C . ALA B 1 131 ? 100.005 -21.286 20.868 1.00 11.20 ? 133 ALA B C 1 ATOM 4333 O O . ALA B 1 131 ? 99.546 -22.224 20.217 1.00 12.10 ? 133 ALA B O 1 ATOM 4334 C CB . ALA B 1 131 ? 98.667 -19.222 21.327 1.00 10.42 ? 133 ALA B CB 1 ATOM 4335 N N . SER B 1 132 ? 101.252 -20.853 20.733 1.00 12.08 ? 134 SER B N 1 ATOM 4336 C CA . SER B 1 132 ? 102.146 -21.397 19.715 1.00 13.69 ? 134 SER B CA 1 ATOM 4337 C C . SER B 1 132 ? 102.545 -22.837 20.022 1.00 13.15 ? 134 SER B C 1 ATOM 4338 O O . SER B 1 132 ? 102.671 -23.666 19.120 1.00 13.45 ? 134 SER B O 1 ATOM 4339 C CB . SER B 1 132 ? 103.393 -20.524 19.584 1.00 15.31 ? 134 SER B CB 1 ATOM 4340 O OG . SER B 1 132 ? 104.186 -20.952 18.492 1.00 19.02 ? 134 SER B OG 1 ATOM 4341 N N . ILE B 1 133 ? 102.751 -23.122 21.302 1.00 12.05 ? 135 ILE B N 1 ATOM 4342 C CA . ILE B 1 133 ? 103.088 -24.464 21.757 1.00 11.59 ? 135 ILE B CA 1 ATOM 4343 C C . ILE B 1 133 ? 101.937 -25.430 21.487 1.00 11.61 ? 135 ILE B C 1 ATOM 4344 O O . ILE B 1 133 ? 102.132 -26.489 20.893 1.00 10.61 ? 135 ILE B O 1 ATOM 4345 C CB . ILE B 1 133 ? 103.442 -24.465 23.259 1.00 11.50 ? 135 ILE B CB 1 ATOM 4346 C CG1 . ILE B 1 133 ? 104.776 -23.745 23.482 1.00 12.53 ? 135 ILE B CG1 1 ATOM 4347 C CG2 . ILE B 1 133 ? 103.505 -25.886 23.797 1.00 11.77 ? 135 ILE B CG2 1 ATOM 4348 C CD1 . ILE B 1 133 ? 105.083 -23.438 24.934 1.00 12.70 ? 135 ILE B CD1 1 ATOM 4349 N N . GLU B 1 134 ? 100.727 -25.014 21.850 1.00 11.61 ? 136 GLU B N 1 ATOM 4350 C CA . GLU B 1 134 ? 99.537 -25.831 21.650 1.00 11.94 ? 136 GLU B CA 1 ATOM 4351 C C . GLU B 1 134 ? 99.267 -26.116 20.175 1.00 11.39 ? 136 GLU B C 1 ATOM 4352 O O . GLU B 1 134 ? 98.921 -27.239 19.808 1.00 11.45 ? 136 GLU B O 1 ATOM 4353 C CB . GLU B 1 134 ? 98.315 -25.176 22.304 1.00 11.83 ? 136 GLU B CB 1 ATOM 4354 C CG . GLU B 1 134 ? 98.372 -25.183 23.824 1.00 12.86 ? 136 GLU B CG 1 ATOM 4355 C CD . GLU B 1 134 ? 97.090 -24.711 24.480 1.00 14.39 ? 136 GLU B CD 1 ATOM 4356 O OE1 . GLU B 1 134 ? 96.221 -24.149 23.778 1.00 13.53 ? 136 GLU B OE1 1 ATOM 4357 O OE2 . GLU B 1 134 ? 96.967 -24.871 25.713 1.00 14.95 ? 136 GLU B OE2 1 ATOM 4358 N N . SER B 1 135 ? 99.411 -25.102 19.330 1.00 11.42 ? 137 SER B N 1 ATOM 4359 C CA . SER B 1 135 ? 99.171 -25.290 17.903 1.00 11.83 ? 137 SER B CA 1 ATOM 4360 C C . SER B 1 135 ? 100.258 -26.155 17.264 1.00 12.16 ? 137 SER B C 1 ATOM 4361 O O . SER B 1 135 ? 99.980 -26.956 16.370 1.00 11.93 ? 137 SER B O 1 ATOM 4362 C CB . SER B 1 135 ? 99.044 -23.945 17.181 1.00 11.94 ? 137 SER B CB 1 ATOM 4363 O OG . SER B 1 135 ? 100.307 -23.331 17.003 1.00 12.33 ? 137 SER B OG 1 ATOM 4364 N N . THR B 1 136 ? 101.488 -26.018 17.752 1.00 12.05 ? 138 THR B N 1 ATOM 4365 C CA . THR B 1 136 ? 102.602 -26.810 17.245 1.00 12.39 ? 138 THR B CA 1 ATOM 4366 C C . THR B 1 136 ? 102.427 -28.292 17.578 1.00 12.26 ? 138 THR B C 1 ATOM 4367 O O . THR B 1 136 ? 102.581 -29.156 16.716 1.00 11.28 ? 138 THR B O 1 ATOM 4368 C CB . THR B 1 136 ? 103.947 -26.321 17.810 1.00 13.97 ? 138 THR B CB 1 ATOM 4369 O OG1 . THR B 1 136 ? 104.206 -24.990 17.346 1.00 14.70 ? 138 THR B OG1 1 ATOM 4370 C CG2 . THR B 1 136 ? 105.078 -27.238 17.361 1.00 15.12 ? 138 THR B CG2 1 ATOM 4371 N N . PHE B 1 137 ? 102.103 -28.578 18.835 1.00 11.76 ? 139 PHE B N 1 ATOM 4372 C CA . PHE B 1 137 ? 101.967 -29.952 19.296 1.00 11.29 ? 139 PHE B CA 1 ATOM 4373 C C . PHE B 1 137 ? 100.633 -30.566 18.881 1.00 12.60 ? 139 PHE B C 1 ATOM 4374 O O . PHE B 1 137 ? 100.518 -31.786 18.739 1.00 12.20 ? 139 PHE B O 1 ATOM 4375 C CB . PHE B 1 137 ? 102.135 -30.024 20.815 1.00 10.98 ? 139 PHE B CB 1 ATOM 4376 C CG . PHE B 1 137 ? 103.569 -30.045 21.261 1.00 11.13 ? 139 PHE B CG 1 ATOM 4377 C CD1 . PHE B 1 137 ? 104.290 -28.869 21.375 1.00 10.94 ? 139 PHE B CD1 1 ATOM 4378 C CD2 . PHE B 1 137 ? 104.215 -31.248 21.496 1.00 11.13 ? 139 PHE B CD2 1 ATOM 4379 C CE1 . PHE B 1 137 ? 105.623 -28.887 21.751 1.00 11.36 ? 139 PHE B CE1 1 ATOM 4380 C CE2 . PHE B 1 137 ? 105.544 -31.273 21.883 1.00 11.24 ? 139 PHE B CE2 1 ATOM 4381 C CZ . PHE B 1 137 ? 106.250 -30.093 22.002 1.00 10.84 ? 139 PHE B CZ 1 ATOM 4382 N N . GLY B 1 138 ? 99.622 -29.719 18.706 1.00 12.62 ? 140 GLY B N 1 ATOM 4383 C CA . GLY B 1 138 ? 98.281 -30.188 18.387 1.00 14.05 ? 140 GLY B CA 1 ATOM 4384 C C . GLY B 1 138 ? 97.767 -31.190 19.404 1.00 14.35 ? 140 GLY B C 1 ATOM 4385 O O . GLY B 1 138 ? 97.938 -31.013 20.612 1.00 13.76 ? 140 GLY B O 1 ATOM 4386 N N . SER B 1 139 ? 97.181 -32.274 18.910 1.00 15.88 ? 141 SER B N 1 ATOM 4387 C CA . SER B 1 139 ? 96.534 -33.255 19.773 1.00 16.74 ? 141 SER B CA 1 ATOM 4388 C C . SER B 1 139 ? 97.534 -34.136 20.524 1.00 15.55 ? 141 SER B C 1 ATOM 4389 O O . SER B 1 139 ? 97.136 -34.997 21.309 1.00 16.22 ? 141 SER B O 1 ATOM 4390 C CB . SER B 1 139 ? 95.593 -34.137 18.953 1.00 18.42 ? 141 SER B CB 1 ATOM 4391 O OG . SER B 1 139 ? 96.295 -34.747 17.885 1.00 24.07 ? 141 SER B OG 1 ATOM 4392 N N . SER B 1 140 ? 98.825 -33.935 20.274 1.00 15.00 ? 142 SER B N 1 ATOM 4393 C CA . SER B 1 140 ? 99.855 -34.748 20.925 1.00 14.79 ? 142 SER B CA 1 ATOM 4394 C C . SER B 1 140 ? 100.078 -34.347 22.384 1.00 15.52 ? 142 SER B C 1 ATOM 4395 O O . SER B 1 140 ? 100.715 -35.072 23.149 1.00 15.27 ? 142 SER B O 1 ATOM 4396 C CB . SER B 1 140 ? 101.169 -34.711 20.142 1.00 14.27 ? 142 SER B CB 1 ATOM 4397 O OG . SER B 1 140 ? 101.842 -33.472 20.288 1.00 14.07 ? 142 SER B OG 1 ATOM 4398 N N . ILE B 1 141 ? 99.507 -33.213 22.774 1.00 16.04 ? 143 ILE B N 1 ATOM 4399 C CA . ILE B 1 141 ? 99.622 -32.721 24.143 1.00 16.04 ? 143 ILE B CA 1 ATOM 4400 C C . ILE B 1 141 ? 98.245 -32.354 24.689 1.00 16.09 ? 143 ILE B C 1 ATOM 4401 O O . ILE B 1 141 ? 97.395 -31.854 23.953 1.00 16.78 ? 143 ILE B O 1 ATOM 4402 C CB . ILE B 1 141 ? 100.539 -31.482 24.200 1.00 16.65 ? 143 ILE B CB 1 ATOM 4403 C CG1 . ILE B 1 141 ? 100.987 -31.198 25.632 1.00 17.89 ? 143 ILE B CG1 1 ATOM 4404 C CG2 . ILE B 1 141 ? 99.839 -30.266 23.615 1.00 16.81 ? 143 ILE B CG2 1 ATOM 4405 C CD1 . ILE B 1 141 ? 102.040 -30.112 25.722 1.00 18.45 ? 143 ILE B CD1 1 ATOM 4406 N N . SER B 1 142 ? 98.013 -32.637 25.968 1.00 15.73 ? 144 SER B N 1 ATOM 4407 C CA . SER B 1 142 ? 96.821 -32.154 26.660 1.00 15.36 ? 144 SER B CA 1 ATOM 4408 C C . SER B 1 142 ? 97.200 -31.287 27.852 1.00 14.53 ? 144 SER B C 1 ATOM 4409 O O . SER B 1 142 ? 98.082 -31.642 28.628 1.00 12.86 ? 144 SER B O 1 ATOM 4410 C CB . SER B 1 142 ? 95.958 -33.327 27.137 1.00 16.04 ? 144 SER B CB 1 ATOM 4411 O OG . SER B 1 142 ? 95.221 -33.896 26.068 1.00 18.62 ? 144 SER B OG 1 ATOM 4412 N N . LYS B 1 143 ? 96.529 -30.150 27.999 1.00 14.52 ? 145 LYS B N 1 ATOM 4413 C CA . LYS B 1 143 ? 96.676 -29.338 29.201 1.00 13.44 ? 145 LYS B CA 1 ATOM 4414 C C . LYS B 1 143 ? 95.830 -29.918 30.329 1.00 13.24 ? 145 LYS B C 1 ATOM 4415 O O . LYS B 1 143 ? 94.619 -30.070 30.188 1.00 13.34 ? 145 LYS B O 1 ATOM 4416 C CB . LYS B 1 143 ? 96.259 -27.891 28.934 1.00 14.47 ? 145 LYS B CB 1 ATOM 4417 C CG . LYS B 1 143 ? 96.517 -26.958 30.107 1.00 15.67 ? 145 LYS B CG 1 ATOM 4418 C CD . LYS B 1 143 ? 95.822 -25.620 29.918 1.00 17.87 ? 145 LYS B CD 1 ATOM 4419 C CE . LYS B 1 143 ? 95.944 -24.770 31.170 1.00 19.44 ? 145 LYS B CE 1 ATOM 4420 N NZ . LYS B 1 143 ? 96.029 -23.317 30.851 1.00 23.06 ? 145 LYS B NZ 1 ATOM 4421 N N . LEU B 1 144 ? 96.468 -30.218 31.454 1.00 11.79 ? 146 LEU B N 1 ATOM 4422 C CA . LEU B 1 144 ? 95.763 -30.790 32.597 1.00 11.71 ? 146 LEU B CA 1 ATOM 4423 C C . LEU B 1 144 ? 95.475 -29.731 33.653 1.00 11.36 ? 146 LEU B C 1 ATOM 4424 O O . LEU B 1 144 ? 94.445 -29.777 34.324 1.00 11.18 ? 146 LEU B O 1 ATOM 4425 C CB . LEU B 1 144 ? 96.575 -31.933 33.215 1.00 11.87 ? 146 LEU B CB 1 ATOM 4426 C CG . LEU B 1 144 ? 96.787 -33.156 32.322 1.00 12.89 ? 146 LEU B CG 1 ATOM 4427 C CD1 . LEU B 1 144 ? 97.417 -34.293 33.113 1.00 12.48 ? 146 LEU B CD1 1 ATOM 4428 C CD2 . LEU B 1 144 ? 95.471 -33.598 31.705 1.00 12.71 ? 146 LEU B CD2 1 ATOM 4429 N N . TYR B 1 145 ? 96.385 -28.771 33.776 1.00 9.92 ? 147 TYR B N 1 ATOM 4430 C CA . TYR B 1 145 ? 96.307 -27.753 34.818 1.00 9.94 ? 147 TYR B CA 1 ATOM 4431 C C . TYR B 1 145 ? 97.341 -26.675 34.518 1.00 9.87 ? 147 TYR B C 1 ATOM 4432 O O . TYR B 1 145 ? 98.369 -26.954 33.904 1.00 9.72 ? 147 TYR B O 1 ATOM 4433 C CB . TYR B 1 145 ? 96.590 -28.378 36.189 1.00 9.72 ? 147 TYR B CB 1 ATOM 4434 C CG . TYR B 1 145 ? 96.439 -27.420 37.350 1.00 9.98 ? 147 TYR B CG 1 ATOM 4435 C CD1 . TYR B 1 145 ? 95.223 -26.796 37.609 1.00 9.85 ? 147 TYR B CD1 1 ATOM 4436 C CD2 . TYR B 1 145 ? 97.513 -27.144 38.193 1.00 10.35 ? 147 TYR B CD2 1 ATOM 4437 C CE1 . TYR B 1 145 ? 95.082 -25.914 38.666 1.00 9.97 ? 147 TYR B CE1 1 ATOM 4438 C CE2 . TYR B 1 145 ? 97.384 -26.263 39.252 1.00 10.20 ? 147 TYR B CE2 1 ATOM 4439 C CZ . TYR B 1 145 ? 96.165 -25.652 39.484 1.00 10.51 ? 147 TYR B CZ 1 ATOM 4440 O OH . TYR B 1 145 ? 96.033 -24.784 40.547 1.00 10.76 ? 147 TYR B OH 1 ATOM 4441 N N . SER B 1 146 ? 97.073 -25.445 34.943 1.00 10.02 ? 148 SER B N 1 ATOM 4442 C CA . SER B 1 146 ? 98.112 -24.419 34.941 1.00 10.55 ? 148 SER B CA 1 ATOM 4443 C C . SER B 1 146 ? 97.984 -23.456 36.112 1.00 10.91 ? 148 SER B C 1 ATOM 4444 O O . SER B 1 146 ? 96.904 -23.286 36.681 1.00 11.50 ? 148 SER B O 1 ATOM 4445 C CB . SER B 1 146 ? 98.125 -23.655 33.613 1.00 10.97 ? 148 SER B CB 1 ATOM 4446 O OG . SER B 1 146 ? 96.955 -22.872 33.464 1.00 11.52 ? 148 SER B OG 1 ATOM 4447 N N . LEU B 1 147 ? 99.105 -22.846 36.481 1.00 10.29 ? 149 LEU B N 1 ATOM 4448 C CA . LEU B 1 147 ? 99.125 -21.837 37.525 1.00 10.41 ? 149 LEU B CA 1 ATOM 4449 C C . LEU B 1 147 ? 99.910 -20.631 37.037 1.00 10.83 ? 149 LEU B C 1 ATOM 4450 O O . LEU B 1 147 ? 101.078 -20.753 36.668 1.00 9.64 ? 149 LEU B O 1 ATOM 4451 C CB . LEU B 1 147 ? 99.759 -22.399 38.803 1.00 9.73 ? 149 LEU B CB 1 ATOM 4452 C CG . LEU B 1 147 ? 99.749 -21.478 40.029 1.00 10.45 ? 149 LEU B CG 1 ATOM 4453 C CD1 . LEU B 1 147 ? 98.326 -21.063 40.383 1.00 9.59 ? 149 LEU B CD1 1 ATOM 4454 C CD2 . LEU B 1 147 ? 100.423 -22.162 41.208 1.00 9.62 ? 149 LEU B CD2 1 ATOM 4455 N N . SER B 1 148 ? 99.252 -19.477 37.003 1.00 11.67 ? 150 SER B N 1 ATOM 4456 C CA . SER B 1 148 ? 99.925 -18.223 36.700 1.00 12.35 ? 150 SER B CA 1 ATOM 4457 C C . SER B 1 148 ? 100.498 -17.593 37.965 1.00 12.91 ? 150 SER B C 1 ATOM 4458 O O . SER B 1 148 ? 99.906 -17.687 39.042 1.00 14.53 ? 150 SER B O 1 ATOM 4459 C CB . SER B 1 148 ? 98.964 -17.255 36.007 1.00 13.78 ? 150 SER B CB 1 ATOM 4460 O OG . SER B 1 148 ? 98.417 -17.847 34.838 1.00 14.22 ? 150 SER B OG 1 ATOM 4461 N N . ALA B 1 149 ? 101.669 -16.982 37.836 1.00 12.25 ? 151 ALA B N 1 ATOM 4462 C CA . ALA B 1 149 ? 102.377 -16.434 38.987 1.00 11.75 ? 151 ALA B CA 1 ATOM 4463 C C . ALA B 1 149 ? 103.030 -15.111 38.610 1.00 11.58 ? 151 ALA B C 1 ATOM 4464 O O . ALA B 1 149 ? 103.199 -14.810 37.432 1.00 11.61 ? 151 ALA B O 1 ATOM 4465 C CB . ALA B 1 149 ? 103.422 -17.422 39.488 1.00 10.70 ? 151 ALA B CB 1 ATOM 4466 N N . SER B 1 150 ? 103.388 -14.323 39.616 1.00 11.06 ? 152 SER B N 1 ATOM 4467 C CA . SER B 1 150 ? 103.901 -12.981 39.379 1.00 11.97 ? 152 SER B CA 1 ATOM 4468 C C . SER B 1 150 ? 104.731 -12.469 40.549 1.00 12.05 ? 152 SER B C 1 ATOM 4469 O O . SER B 1 150 ? 104.405 -12.711 41.713 1.00 11.78 ? 152 SER B O 1 ATOM 4470 C CB . SER B 1 150 ? 102.748 -12.012 39.099 1.00 13.10 ? 152 SER B CB 1 ATOM 4471 O OG . SER B 1 150 ? 103.232 -10.707 38.831 1.00 12.95 ? 152 SER B OG 1 ATOM 4472 N N . ILE B 1 151 ? 105.804 -11.754 40.228 1.00 12.19 ? 153 ILE B N 1 ATOM 4473 C CA . ILE B 1 151 ? 106.449 -10.864 41.184 1.00 12.95 ? 153 ILE B CA 1 ATOM 4474 C C . ILE B 1 151 ? 105.426 -9.857 41.694 1.00 13.14 ? 153 ILE B C 1 ATOM 4475 O O . ILE B 1 151 ? 104.601 -9.361 40.926 1.00 12.14 ? 153 ILE B O 1 ATOM 4476 C CB . ILE B 1 151 ? 107.620 -10.107 40.525 1.00 13.69 ? 153 ILE B CB 1 ATOM 4477 C CG1 . ILE B 1 151 ? 108.557 -11.088 39.814 1.00 14.38 ? 153 ILE B CG1 1 ATOM 4478 C CG2 . ILE B 1 151 ? 108.381 -9.283 41.551 1.00 14.07 ? 153 ILE B CG2 1 ATOM 4479 C CD1 . ILE B 1 151 ? 109.070 -12.199 40.706 1.00 15.31 ? 153 ILE B CD1 1 ATOM 4480 N N . ARG B 1 152 ? 105.463 -9.581 42.995 1.00 12.20 ? 154 ARG B N 1 ATOM 4481 C CA . ARG B 1 152 ? 104.516 -8.663 43.605 1.00 12.67 ? 154 ARG B CA 1 ATOM 4482 C C . ARG B 1 152 ? 104.874 -7.216 43.271 1.00 13.83 ? 154 ARG B C 1 ATOM 4483 O O . ARG B 1 152 ? 105.999 -6.932 42.863 1.00 13.48 ? 154 ARG B O 1 ATOM 4484 C CB . ARG B 1 152 ? 104.454 -8.886 45.119 1.00 13.14 ? 154 ARG B CB 1 ATOM 4485 C CG . ARG B 1 152 ? 103.936 -10.265 45.505 1.00 13.16 ? 154 ARG B CG 1 ATOM 4486 C CD . ARG B 1 152 ? 103.626 -10.352 46.991 1.00 13.72 ? 154 ARG B CD 1 ATOM 4487 N NE . ARG B 1 152 ? 102.837 -9.206 47.425 1.00 13.59 ? 154 ARG B NE 1 ATOM 4488 C CZ . ARG B 1 152 ? 103.034 -8.548 48.560 1.00 13.83 ? 154 ARG B CZ 1 ATOM 4489 N NH1 . ARG B 1 152 ? 103.988 -8.933 49.400 1.00 13.96 ? 154 ARG B NH1 1 ATOM 4490 N NH2 . ARG B 1 152 ? 102.281 -7.496 48.848 1.00 14.24 ? 154 ARG B NH2 1 ATOM 4491 N N . PRO B 1 153 ? 103.893 -6.308 43.379 1.00 14.69 ? 155 PRO B N 1 ATOM 4492 C CA . PRO B 1 153 ? 104.024 -4.980 42.782 1.00 15.81 ? 155 PRO B CA 1 ATOM 4493 C C . PRO B 1 153 ? 104.897 -4.040 43.608 1.00 16.33 ? 155 PRO B C 1 ATOM 4494 O O . PRO B 1 153 ? 105.027 -4.216 44.819 1.00 15.63 ? 155 PRO B O 1 ATOM 4495 C CB . PRO B 1 153 ? 102.581 -4.467 42.740 1.00 16.36 ? 155 PRO B CB 1 ATOM 4496 C CG . PRO B 1 153 ? 101.865 -5.234 43.795 1.00 16.72 ? 155 PRO B CG 1 ATOM 4497 C CD . PRO B 1 153 ? 102.522 -6.581 43.846 1.00 14.99 ? 155 PRO B CD 1 ATOM 4498 N N . GLY B 1 154 ? 105.515 -3.070 42.938 1.00 17.01 ? 156 GLY B N 1 ATOM 4499 C CA . GLY B 1 154 ? 106.145 -1.935 43.611 1.00 17.69 ? 156 GLY B CA 1 ATOM 4500 C C . GLY B 1 154 ? 107.167 -2.320 44.663 1.00 18.87 ? 156 GLY B C 1 ATOM 4501 O O . GLY B 1 154 ? 108.099 -3.081 44.395 1.00 17.76 ? 156 GLY B O 1 ATOM 4502 N N . ASN B 1 155 ? 106.983 -1.793 45.870 1.00 21.11 ? 157 ASN B N 1 ATOM 4503 C CA . ASN B 1 155 ? 107.930 -1.992 46.963 1.00 22.64 ? 157 ASN B CA 1 ATOM 4504 C C . ASN B 1 155 ? 107.975 -3.427 47.464 1.00 20.18 ? 157 ASN B C 1 ATOM 4505 O O . ASN B 1 155 ? 108.858 -3.792 48.239 1.00 21.83 ? 157 ASN B O 1 ATOM 4506 C CB . ASN B 1 155 ? 107.593 -1.065 48.134 1.00 25.21 ? 157 ASN B CB 1 ATOM 4507 C CG . ASN B 1 155 ? 108.443 0.186 48.143 1.00 28.09 ? 157 ASN B CG 1 ATOM 4508 O OD1 . ASN B 1 155 ? 109.454 0.267 47.444 1.00 29.27 ? 157 ASN B OD1 1 ATOM 4509 N ND2 . ASN B 1 155 ? 108.038 1.171 48.935 1.00 33.46 ? 157 ASN B ND2 1 ATOM 4510 N N . GLU B 1 156 ? 106.975 -4.214 47.086 1.00 18.87 ? 158 GLU B N 1 ATOM 4511 C CA . GLU B 1 156 ? 106.884 -5.592 47.545 1.00 18.04 ? 158 GLU B CA 1 ATOM 4512 C C . GLU B 1 156 ? 107.446 -6.557 46.507 1.00 16.13 ? 158 GLU B C 1 ATOM 4513 O O . GLU B 1 156 ? 107.350 -7.775 46.662 1.00 15.05 ? 158 GLU B O 1 ATOM 4514 C CB . GLU B 1 156 ? 105.434 -5.948 47.882 1.00 19.36 ? 158 GLU B CB 1 ATOM 4515 C CG . GLU B 1 156 ? 104.879 -5.196 49.083 1.00 20.38 ? 158 GLU B CG 1 ATOM 4516 C CD . GLU B 1 156 ? 105.497 -5.654 50.389 1.00 23.15 ? 158 GLU B CD 1 ATOM 4517 O OE1 . GLU B 1 156 ? 105.597 -6.880 50.605 1.00 22.50 ? 158 GLU B OE1 1 ATOM 4518 O OE2 . GLU B 1 156 ? 105.893 -4.789 51.199 1.00 25.63 ? 158 GLU B OE2 1 ATOM 4519 N N . ALA B 1 157 ? 108.038 -6.011 45.449 1.00 15.44 ? 159 ALA B N 1 ATOM 4520 C CA . ALA B 1 157 ? 108.698 -6.842 44.448 1.00 14.94 ? 159 ALA B CA 1 ATOM 4521 C C . ALA B 1 157 ? 109.815 -7.643 45.104 1.00 14.66 ? 159 ALA B C 1 ATOM 4522 O O . ALA B 1 157 ? 110.679 -7.079 45.775 1.00 15.14 ? 159 ALA B O 1 ATOM 4523 C CB . ALA B 1 157 ? 109.248 -5.985 43.316 1.00 15.32 ? 159 ALA B CB 1 ATOM 4524 N N . GLY B 1 158 ? 109.781 -8.959 44.920 1.00 13.84 ? 160 GLY B N 1 ATOM 4525 C CA . GLY B 1 158 ? 110.753 -9.850 45.547 1.00 13.84 ? 160 GLY B CA 1 ATOM 4526 C C . GLY B 1 158 ? 110.311 -10.332 46.918 1.00 13.63 ? 160 GLY B C 1 ATOM 4527 O O . GLY B 1 158 ? 110.988 -11.145 47.544 1.00 14.21 ? 160 GLY B O 1 ATOM 4528 N N . HIS B 1 159 ? 109.193 -9.802 47.405 1.00 13.06 ? 161 HIS B N 1 ATOM 4529 C CA . HIS B 1 159 ? 108.598 -10.293 48.645 1.00 13.11 ? 161 HIS B CA 1 ATOM 4530 C C . HIS B 1 159 ? 107.521 -11.320 48.311 1.00 12.83 ? 161 HIS B C 1 ATOM 4531 O O . HIS B 1 159 ? 106.917 -11.270 47.238 1.00 13.06 ? 161 HIS B O 1 ATOM 4532 C CB . HIS B 1 159 ? 107.985 -9.141 49.447 1.00 13.28 ? 161 HIS B CB 1 ATOM 4533 C CG . HIS B 1 159 ? 108.978 -8.117 49.907 1.00 13.54 ? 161 HIS B CG 1 ATOM 4534 N ND1 . HIS B 1 159 ? 109.099 -7.743 51.229 1.00 13.88 ? 161 HIS B ND1 1 ATOM 4535 C CD2 . HIS B 1 159 ? 109.829 -7.326 49.214 1.00 13.71 ? 161 HIS B CD2 1 ATOM 4536 C CE1 . HIS B 1 159 ? 110.011 -6.793 51.334 1.00 13.54 ? 161 HIS B CE1 1 ATOM 4537 N NE2 . HIS B 1 159 ? 110.475 -6.527 50.126 1.00 14.52 ? 161 HIS B NE2 1 ATOM 4538 N N . GLU B 1 160 ? 107.287 -12.261 49.217 1.00 12.76 ? 162 GLU B N 1 ATOM 4539 C CA . GLU B 1 160 ? 106.168 -13.177 49.047 1.00 13.35 ? 162 GLU B CA 1 ATOM 4540 C C . GLU B 1 160 ? 104.916 -12.633 49.727 1.00 13.25 ? 162 GLU B C 1 ATOM 4541 O O . GLU B 1 160 ? 104.899 -11.488 50.184 1.00 12.22 ? 162 GLU B O 1 ATOM 4542 C CB . GLU B 1 160 ? 106.517 -14.587 49.532 1.00 14.51 ? 162 GLU B CB 1 ATOM 4543 C CG . GLU B 1 160 ? 107.100 -14.649 50.929 1.00 15.26 ? 162 GLU B CG 1 ATOM 4544 C CD . GLU B 1 160 ? 106.057 -14.390 51.996 1.00 16.04 ? 162 GLU B CD 1 ATOM 4545 O OE1 . GLU B 1 160 ? 105.001 -15.060 51.973 1.00 16.98 ? 162 GLU B OE1 1 ATOM 4546 O OE2 . GLU B 1 160 ? 106.290 -13.511 52.851 1.00 16.72 ? 162 GLU B OE2 1 ATOM 4547 N N . MET B 1 161 ? 103.852 -13.431 49.742 1.00 12.93 ? 163 MET B N 1 ATOM 4548 C CA . MET B 1 161 ? 102.524 -12.913 50.059 1.00 12.55 ? 163 MET B CA 1 ATOM 4549 C C . MET B 1 161 ? 102.363 -12.496 51.524 1.00 12.58 ? 163 MET B C 1 ATOM 4550 O O . MET B 1 161 ? 101.528 -11.648 51.838 1.00 13.28 ? 163 MET B O 1 ATOM 4551 C CB . MET B 1 161 ? 101.436 -13.911 49.651 1.00 12.41 ? 163 MET B CB 1 ATOM 4552 C CG . MET B 1 161 ? 101.053 -13.850 48.178 1.00 12.58 ? 163 MET B CG 1 ATOM 4553 S SD . MET B 1 161 ? 100.239 -12.299 47.733 1.00 12.91 ? 163 MET B SD 1 ATOM 4554 C CE . MET B 1 161 ? 100.257 -12.397 45.939 1.00 12.31 ? 163 MET B CE 1 ATOM 4555 N N . PHE B 1 162 ? 103.137 -13.102 52.421 1.00 13.14 ? 164 PHE B N 1 ATOM 4556 C CA . PHE B 1 162 ? 103.127 -12.687 53.830 1.00 13.56 ? 164 PHE B CA 1 ATOM 4557 C C . PHE B 1 162 ? 103.847 -11.351 54.002 1.00 13.48 ? 164 PHE B C 1 ATOM 4558 O O . PHE B 1 162 ? 103.713 -10.690 55.031 1.00 14.89 ? 164 PHE B O 1 ATOM 4559 C CB . PHE B 1 162 ? 103.770 -13.747 54.736 1.00 13.04 ? 164 PHE B CB 1 ATOM 4560 C CG . PHE B 1 162 ? 102.913 -14.961 54.962 1.00 13.41 ? 164 PHE B CG 1 ATOM 4561 C CD1 . PHE B 1 162 ? 101.535 -14.847 55.076 1.00 12.70 ? 164 PHE B CD1 1 ATOM 4562 C CD2 . PHE B 1 162 ? 103.490 -16.215 55.097 1.00 14.54 ? 164 PHE B CD2 1 ATOM 4563 C CE1 . PHE B 1 162 ? 100.747 -15.965 55.282 1.00 13.21 ? 164 PHE B CE1 1 ATOM 4564 C CE2 . PHE B 1 162 ? 102.709 -17.337 55.313 1.00 13.96 ? 164 PHE B CE2 1 ATOM 4565 C CZ . PHE B 1 162 ? 101.334 -17.213 55.401 1.00 13.64 ? 164 PHE B CZ 1 ATOM 4566 N N . GLY B 1 163 ? 104.645 -10.981 53.007 1.00 13.20 ? 165 GLY B N 1 ATOM 4567 C CA . GLY B 1 163 ? 105.289 -9.673 52.985 1.00 12.58 ? 165 GLY B CA 1 ATOM 4568 C C . GLY B 1 163 ? 106.794 -9.701 53.192 1.00 12.59 ? 165 GLY B C 1 ATOM 4569 O O . GLY B 1 163 ? 107.429 -8.651 53.281 1.00 12.45 ? 165 GLY B O 1 ATOM 4570 N N . PHE B 1 164 ? 107.373 -10.897 53.251 1.00 12.22 ? 166 PHE B N 1 ATOM 4571 C CA . PHE B 1 164 ? 108.803 -11.035 53.525 1.00 12.91 ? 166 PHE B CA 1 ATOM 4572 C C . PHE B 1 164 ? 109.649 -11.109 52.259 1.00 13.06 ? 166 PHE B C 1 ATOM 4573 O O . PHE B 1 164 ? 109.313 -11.830 51.318 1.00 12.30 ? 166 PHE B O 1 ATOM 4574 C CB . PHE B 1 164 ? 109.068 -12.254 54.407 1.00 13.22 ? 166 PHE B CB 1 ATOM 4575 C CG . PHE B 1 164 ? 108.490 -12.132 55.786 1.00 12.74 ? 166 PHE B CG 1 ATOM 4576 C CD1 . PHE B 1 164 ? 107.139 -12.343 56.004 1.00 12.78 ? 166 PHE B CD1 1 ATOM 4577 C CD2 . PHE B 1 164 ? 109.288 -11.772 56.856 1.00 13.11 ? 166 PHE B CD2 1 ATOM 4578 C CE1 . PHE B 1 164 ? 106.596 -12.200 57.267 1.00 13.18 ? 166 PHE B CE1 1 ATOM 4579 C CE2 . PHE B 1 164 ? 108.754 -11.629 58.121 1.00 12.84 ? 166 PHE B CE2 1 ATOM 4580 C CZ . PHE B 1 164 ? 107.406 -11.844 58.329 1.00 12.80 ? 166 PHE B CZ 1 ATOM 4581 N N . LEU B 1 165 ? 110.755 -10.369 52.248 1.00 13.03 ? 167 LEU B N 1 ATOM 4582 C CA . LEU B 1 165 ? 111.721 -10.466 51.160 1.00 13.72 ? 167 LEU B CA 1 ATOM 4583 C C . LEU B 1 165 ? 112.202 -11.903 51.031 1.00 14.36 ? 167 LEU B C 1 ATOM 4584 O O . LEU B 1 165 ? 112.575 -12.532 52.019 1.00 14.34 ? 167 LEU B O 1 ATOM 4585 C CB . LEU B 1 165 ? 112.910 -9.533 51.395 1.00 13.65 ? 167 LEU B CB 1 ATOM 4586 C CG . LEU B 1 165 ? 113.884 -9.397 50.221 1.00 14.06 ? 167 LEU B CG 1 ATOM 4587 C CD1 . LEU B 1 165 ? 113.191 -8.767 49.020 1.00 14.17 ? 167 LEU B CD1 1 ATOM 4588 C CD2 . LEU B 1 165 ? 115.124 -8.604 50.613 1.00 13.79 ? 167 LEU B CD2 1 ATOM 4589 N N A ASP B 1 166 ? 112.196 -12.415 49.805 0.50 15.22 ? 168 ASP B N 1 ATOM 4590 N N B ASP B 1 166 ? 112.153 -12.431 49.814 0.50 15.73 ? 168 ASP B N 1 ATOM 4591 C CA A ASP B 1 166 ? 112.494 -13.821 49.564 0.50 17.14 ? 168 ASP B CA 1 ATOM 4592 C CA B ASP B 1 166 ? 112.510 -13.822 49.578 0.50 17.42 ? 168 ASP B CA 1 ATOM 4593 C C A ASP B 1 166 ? 113.542 -13.977 48.465 0.50 18.49 ? 168 ASP B C 1 ATOM 4594 C C B ASP B 1 166 ? 113.702 -13.923 48.633 0.50 18.47 ? 168 ASP B C 1 ATOM 4595 O O A ASP B 1 166 ? 113.769 -13.059 47.675 0.50 20.04 ? 168 ASP B O 1 ATOM 4596 O O B ASP B 1 166 ? 114.191 -12.914 48.124 0.50 19.90 ? 168 ASP B O 1 ATOM 4597 C CB A ASP B 1 166 ? 111.214 -14.577 49.197 0.50 17.95 ? 168 ASP B CB 1 ATOM 4598 C CB B ASP B 1 166 ? 111.311 -14.596 49.022 0.50 18.72 ? 168 ASP B CB 1 ATOM 4599 C CG A ASP B 1 166 ? 111.417 -16.077 49.154 0.50 18.83 ? 168 ASP B CG 1 ATOM 4600 C CG B ASP B 1 166 ? 110.906 -14.129 47.637 0.50 19.19 ? 168 ASP B CG 1 ATOM 4601 O OD1 A ASP B 1 166 ? 112.571 -16.525 49.322 0.50 17.96 ? 168 ASP B OD1 1 ATOM 4602 O OD1 B ASP B 1 166 ? 111.796 -13.724 46.859 0.50 19.64 ? 168 ASP B OD1 1 ATOM 4603 O OD2 A ASP B 1 166 ? 110.425 -16.807 48.944 0.50 20.38 ? 168 ASP B OD2 1 ATOM 4604 O OD2 B ASP B 1 166 ? 109.698 -14.179 47.320 0.50 22.03 ? 168 ASP B OD2 1 ATOM 4605 N N . GLY B 1 167 ? 114.180 -15.143 48.419 1.00 19.24 ? 169 GLY B N 1 ATOM 4606 C CA . GLY B 1 167 ? 115.275 -15.377 47.485 1.00 18.28 ? 169 GLY B CA 1 ATOM 4607 C C . GLY B 1 167 ? 116.558 -14.674 47.884 1.00 17.51 ? 169 GLY B C 1 ATOM 4608 O O . GLY B 1 167 ? 117.360 -14.291 47.032 1.00 18.30 ? 169 GLY B O 1 ATOM 4609 N N . ILE B 1 168 ? 116.750 -14.490 49.184 1.00 16.37 ? 170 ILE B N 1 ATOM 4610 C CA . ILE B 1 168 ? 118.026 -14.015 49.698 1.00 15.09 ? 170 ILE B CA 1 ATOM 4611 C C . ILE B 1 168 ? 119.045 -15.150 49.722 1.00 14.05 ? 170 ILE B C 1 ATOM 4612 O O . ILE B 1 168 ? 120.175 -14.991 49.267 1.00 14.10 ? 170 ILE B O 1 ATOM 4613 C CB . ILE B 1 168 ? 117.886 -13.444 51.122 1.00 15.57 ? 170 ILE B CB 1 ATOM 4614 C CG1 . ILE B 1 168 ? 116.994 -12.199 51.112 1.00 15.94 ? 170 ILE B CG1 1 ATOM 4615 C CG2 . ILE B 1 168 ? 119.253 -13.103 51.692 1.00 14.97 ? 170 ILE B CG2 1 ATOM 4616 C CD1 . ILE B 1 168 ? 116.571 -11.741 52.492 1.00 16.75 ? 170 ILE B CD1 1 ATOM 4617 N N . ALA B 1 169 ? 118.634 -16.297 50.252 1.00 14.20 ? 171 ALA B N 1 ATOM 4618 C CA . ALA B 1 169 ? 119.576 -17.350 50.622 1.00 13.37 ? 171 ALA B CA 1 ATOM 4619 C C . ALA B 1 169 ? 119.500 -18.567 49.698 1.00 13.40 ? 171 ALA B C 1 ATOM 4620 O O . ALA B 1 169 ? 118.443 -19.178 49.547 1.00 14.49 ? 171 ALA B O 1 ATOM 4621 C CB . ALA B 1 169 ? 119.365 -17.760 52.071 1.00 13.62 ? 171 ALA B CB 1 ATOM 4622 N N . GLN B 1 170 ? 120.627 -18.896 49.070 1.00 12.79 ? 172 GLN B N 1 ATOM 4623 C CA . GLN B 1 170 ? 120.755 -20.102 48.252 1.00 12.67 ? 172 GLN B CA 1 ATOM 4624 C C . GLN B 1 170 ? 122.129 -20.726 48.496 1.00 12.26 ? 172 GLN B C 1 ATOM 4625 O O . GLN B 1 170 ? 123.068 -20.032 48.865 1.00 12.40 ? 172 GLN B O 1 ATOM 4626 C CB . GLN B 1 170 ? 120.618 -19.757 46.766 1.00 12.66 ? 172 GLN B CB 1 ATOM 4627 C CG . GLN B 1 170 ? 119.457 -18.832 46.434 1.00 13.61 ? 172 GLN B CG 1 ATOM 4628 C CD . GLN B 1 170 ? 118.178 -19.587 46.125 1.00 14.22 ? 172 GLN B CD 1 ATOM 4629 O OE1 . GLN B 1 170 ? 118.048 -20.769 46.448 1.00 13.02 ? 172 GLN B OE1 1 ATOM 4630 N NE2 . GLN B 1 170 ? 117.217 -18.900 45.508 1.00 15.03 ? 172 GLN B NE2 1 ATOM 4631 N N . PRO B 1 171 ? 122.260 -22.040 48.274 1.00 12.25 ? 173 PRO B N 1 ATOM 4632 C CA . PRO B 1 171 ? 123.606 -22.604 48.309 1.00 11.91 ? 173 PRO B CA 1 ATOM 4633 C C . PRO B 1 171 ? 124.451 -22.033 47.178 1.00 12.48 ? 173 PRO B C 1 ATOM 4634 O O . PRO B 1 171 ? 123.935 -21.798 46.083 1.00 13.34 ? 173 PRO B O 1 ATOM 4635 C CB . PRO B 1 171 ? 123.369 -24.102 48.093 1.00 11.32 ? 173 PRO B CB 1 ATOM 4636 C CG . PRO B 1 171 ? 122.037 -24.190 47.423 1.00 11.26 ? 173 PRO B CG 1 ATOM 4637 C CD . PRO B 1 171 ? 121.232 -23.052 47.981 1.00 11.28 ? 173 PRO B CD 1 ATOM 4638 N N . ALA B 1 172 ? 125.717 -21.742 47.465 1.00 12.08 ? 174 ALA B N 1 ATOM 4639 C CA . ALA B 1 172 ? 126.681 -21.433 46.418 1.00 12.49 ? 174 ALA B CA 1 ATOM 4640 C C . ALA B 1 172 ? 127.269 -22.728 45.874 1.00 13.45 ? 174 ALA B C 1 ATOM 4641 O O . ALA B 1 172 ? 127.689 -23.595 46.638 1.00 13.59 ? 174 ALA B O 1 ATOM 4642 C CB . ALA B 1 172 ? 127.783 -20.532 46.955 1.00 12.80 ? 174 ALA B CB 1 ATOM 4643 N N . ILE B 1 173 ? 127.249 -22.872 44.553 1.00 14.18 ? 175 ILE B N 1 ATOM 4644 C CA . ILE B 1 173 ? 127.829 -24.037 43.905 1.00 15.22 ? 175 ILE B CA 1 ATOM 4645 C C . ILE B 1 173 ? 129.330 -23.831 43.750 1.00 16.00 ? 175 ILE B C 1 ATOM 4646 O O . ILE B 1 173 ? 129.767 -22.939 43.024 1.00 15.65 ? 175 ILE B O 1 ATOM 4647 C CB . ILE B 1 173 ? 127.213 -24.271 42.513 1.00 15.55 ? 175 ILE B CB 1 ATOM 4648 C CG1 . ILE B 1 173 ? 125.709 -24.540 42.621 1.00 16.53 ? 175 ILE B CG1 1 ATOM 4649 C CG2 . ILE B 1 173 ? 127.931 -25.406 41.798 1.00 15.37 ? 175 ILE B CG2 1 ATOM 4650 C CD1 . ILE B 1 173 ? 125.351 -25.683 43.545 1.00 16.46 ? 175 ILE B CD1 1 ATOM 4651 N N . ASN B 1 174 ? 130.112 -24.631 44.467 1.00 16.95 ? 176 ASN B N 1 ATOM 4652 C CA . ASN B 1 174 ? 131.566 -24.541 44.401 1.00 18.03 ? 176 ASN B CA 1 ATOM 4653 C C . ASN B 1 174 ? 132.067 -24.686 42.969 1.00 18.76 ? 176 ASN B C 1 ATOM 4654 O O . ASN B 1 174 ? 131.780 -25.677 42.301 1.00 18.99 ? 176 ASN B O 1 ATOM 4655 C CB . ASN B 1 174 ? 132.210 -25.604 45.295 1.00 19.29 ? 176 ASN B CB 1 ATOM 4656 C CG . ASN B 1 174 ? 133.719 -25.473 45.361 1.00 20.82 ? 176 ASN B CG 1 ATOM 4657 O OD1 . ASN B 1 174 ? 134.259 -24.368 45.329 1.00 21.99 ? 176 ASN B OD1 1 ATOM 4658 N ND2 . ASN B 1 174 ? 134.408 -26.604 45.455 1.00 22.30 ? 176 ASN B ND2 1 ATOM 4659 N N . GLY B 1 175 ? 132.787 -23.675 42.495 1.00 19.30 ? 177 GLY B N 1 ATOM 4660 C CA . GLY B 1 175 ? 133.343 -23.696 41.151 1.00 19.48 ? 177 GLY B CA 1 ATOM 4661 C C . GLY B 1 175 ? 132.459 -23.002 40.133 1.00 19.74 ? 177 GLY B C 1 ATOM 4662 O O . GLY B 1 175 ? 132.841 -22.851 38.973 1.00 21.48 ? 177 GLY B O 1 ATOM 4663 N N . PHE B 1 176 ? 131.263 -22.603 40.555 1.00 18.28 ? 178 PHE B N 1 ATOM 4664 C CA . PHE B 1 176 ? 130.370 -21.842 39.692 1.00 17.98 ? 178 PHE B CA 1 ATOM 4665 C C . PHE B 1 176 ? 129.999 -20.503 40.322 1.00 18.69 ? 178 PHE B C 1 ATOM 4666 O O . PHE B 1 176 ? 130.170 -19.451 39.708 1.00 18.04 ? 178 PHE B O 1 ATOM 4667 C CB . PHE B 1 176 ? 129.110 -22.648 39.359 1.00 18.25 ? 178 PHE B CB 1 ATOM 4668 C CG . PHE B 1 176 ? 128.025 -21.833 38.714 1.00 18.39 ? 178 PHE B CG 1 ATOM 4669 C CD1 . PHE B 1 176 ? 128.217 -21.265 37.465 1.00 18.67 ? 178 PHE B CD1 1 ATOM 4670 C CD2 . PHE B 1 176 ? 126.827 -21.605 39.372 1.00 17.32 ? 178 PHE B CD2 1 ATOM 4671 C CE1 . PHE B 1 176 ? 127.234 -20.484 36.882 1.00 18.59 ? 178 PHE B CE1 1 ATOM 4672 C CE2 . PHE B 1 176 ? 125.836 -20.837 38.789 1.00 17.38 ? 178 PHE B CE2 1 ATOM 4673 C CZ . PHE B 1 176 ? 126.037 -20.281 37.539 1.00 17.51 ? 178 PHE B CZ 1 ATOM 4674 N N . ASN B 1 177 ? 129.508 -20.548 41.556 1.00 18.33 ? 179 ASN B N 1 ATOM 4675 C CA . ASN B 1 177 ? 129.107 -19.337 42.265 1.00 19.62 ? 179 ASN B CA 1 ATOM 4676 C C . ASN B 1 177 ? 130.271 -18.713 43.016 1.00 19.91 ? 179 ASN B C 1 ATOM 4677 O O . ASN B 1 177 ? 131.089 -19.415 43.608 1.00 20.49 ? 179 ASN B O 1 ATOM 4678 C CB . ASN B 1 177 ? 127.980 -19.638 43.254 1.00 18.52 ? 179 ASN B CB 1 ATOM 4679 C CG . ASN B 1 177 ? 126.671 -19.944 42.566 1.00 18.25 ? 179 ASN B CG 1 ATOM 4680 O OD1 . ASN B 1 177 ? 126.068 -20.992 42.796 1.00 17.49 ? 179 ASN B OD1 1 ATOM 4681 N ND2 . ASN B 1 177 ? 126.218 -19.026 41.718 1.00 18.66 ? 179 ASN B ND2 1 ATOM 4682 N N . THR B 1 178 ? 130.328 -17.387 42.999 1.00 21.11 ? 180 THR B N 1 ATOM 4683 C CA . THR B 1 178 ? 131.167 -16.645 43.927 1.00 20.91 ? 180 THR B CA 1 ATOM 4684 C C . THR B 1 178 ? 130.418 -16.450 45.235 1.00 19.84 ? 180 THR B C 1 ATOM 4685 O O . THR B 1 178 ? 129.443 -15.702 45.287 1.00 20.96 ? 180 THR B O 1 ATOM 4686 C CB . THR B 1 178 ? 131.539 -15.264 43.358 1.00 23.45 ? 180 THR B CB 1 ATOM 4687 O OG1 . THR B 1 178 ? 132.115 -15.424 42.058 1.00 25.18 ? 180 THR B OG1 1 ATOM 4688 C CG2 . THR B 1 178 ? 132.533 -14.570 44.264 1.00 23.60 ? 180 THR B CG2 1 ATOM 4689 N N . PRO B 1 179 ? 130.857 -17.143 46.294 1.00 18.94 ? 181 PRO B N 1 ATOM 4690 C CA . PRO B 1 179 ? 130.113 -17.191 47.547 1.00 19.20 ? 181 PRO B CA 1 ATOM 4691 C C . PRO B 1 179 ? 129.952 -15.808 48.174 1.00 18.69 ? 181 PRO B C 1 ATOM 4692 O O . PRO B 1 179 ? 130.865 -14.987 48.110 1.00 19.06 ? 181 PRO B O 1 ATOM 4693 C CB . PRO B 1 179 ? 130.984 -18.081 48.445 1.00 20.37 ? 181 PRO B CB 1 ATOM 4694 C CG . PRO B 1 179 ? 131.853 -18.853 47.508 1.00 21.20 ? 181 PRO B CG 1 ATOM 4695 C CD . PRO B 1 179 ? 132.103 -17.925 46.357 1.00 19.07 ? 181 PRO B CD 1 ATOM 4696 N N . LEU B 1 180 ? 128.785 -15.556 48.757 1.00 17.70 ? 182 LEU B N 1 ATOM 4697 C CA . LEU B 1 180 ? 128.568 -14.370 49.577 1.00 16.89 ? 182 LEU B CA 1 ATOM 4698 C C . LEU B 1 180 ? 128.825 -14.699 51.047 1.00 15.95 ? 182 LEU B C 1 ATOM 4699 O O . LEU B 1 180 ? 128.761 -15.862 51.447 1.00 15.80 ? 182 LEU B O 1 ATOM 4700 C CB . LEU B 1 180 ? 127.136 -13.857 49.399 1.00 16.43 ? 182 LEU B CB 1 ATOM 4701 C CG . LEU B 1 180 ? 126.686 -13.553 47.967 1.00 17.11 ? 182 LEU B CG 1 ATOM 4702 C CD1 . LEU B 1 180 ? 125.169 -13.494 47.880 1.00 16.22 ? 182 LEU B CD1 1 ATOM 4703 C CD2 . LEU B 1 180 ? 127.302 -12.248 47.488 1.00 16.54 ? 182 LEU B CD2 1 ATOM 4704 N N . PRO B 1 181 ? 129.109 -13.674 51.862 1.00 15.47 ? 183 PRO B N 1 ATOM 4705 C CA . PRO B 1 181 ? 129.357 -13.915 53.279 1.00 14.92 ? 183 PRO B CA 1 ATOM 4706 C C . PRO B 1 181 ? 128.237 -14.714 53.935 1.00 13.94 ? 183 PRO B C 1 ATOM 4707 O O . PRO B 1 181 ? 127.068 -14.329 53.857 1.00 13.82 ? 183 PRO B O 1 ATOM 4708 C CB . PRO B 1 181 ? 129.421 -12.504 53.859 1.00 14.54 ? 183 PRO B CB 1 ATOM 4709 C CG . PRO B 1 181 ? 129.980 -11.688 52.742 1.00 15.32 ? 183 PRO B CG 1 ATOM 4710 C CD . PRO B 1 181 ? 129.433 -12.289 51.472 1.00 15.97 ? 183 PRO B CD 1 ATOM 4711 N N . GLY B 1 182 ? 128.599 -15.823 54.572 1.00 13.14 ? 184 GLY B N 1 ATOM 4712 C CA . GLY B 1 182 ? 127.645 -16.637 55.313 1.00 12.30 ? 184 GLY B CA 1 ATOM 4713 C C . GLY B 1 182 ? 127.031 -17.745 54.473 1.00 12.68 ? 184 GLY B C 1 ATOM 4714 O O . GLY B 1 182 ? 126.519 -18.728 55.004 1.00 11.69 ? 184 GLY B O 1 ATOM 4715 N N . GLN B 1 183 ? 127.102 -17.588 53.155 1.00 12.40 ? 185 GLN B N 1 ATOM 4716 C CA . GLN B 1 183 ? 126.483 -18.530 52.226 1.00 13.00 ? 185 GLN B CA 1 ATOM 4717 C C . GLN B 1 183 ? 127.124 -19.911 52.349 1.00 12.69 ? 185 GLN B C 1 ATOM 4718 O O . GLN B 1 183 ? 128.344 -20.029 52.437 1.00 12.71 ? 185 GLN B O 1 ATOM 4719 C CB . GLN B 1 183 ? 126.635 -18.010 50.794 1.00 13.41 ? 185 GLN B CB 1 ATOM 4720 C CG . GLN B 1 183 ? 125.638 -18.573 49.795 1.00 13.38 ? 185 GLN B CG 1 ATOM 4721 C CD . GLN B 1 183 ? 125.818 -17.986 48.408 1.00 13.97 ? 185 GLN B CD 1 ATOM 4722 O OE1 . GLN B 1 183 ? 126.773 -17.249 48.149 1.00 14.44 ? 185 GLN B OE1 1 ATOM 4723 N NE2 . GLN B 1 183 ? 124.905 -18.320 47.500 1.00 12.91 ? 185 GLN B NE2 1 ATOM 4724 N N . ASN B 1 184 ? 126.306 -20.959 52.345 1.00 12.13 ? 186 ASN B N 1 ATOM 4725 C CA . ASN B 1 184 ? 126.842 -22.311 52.251 1.00 11.75 ? 186 ASN B CA 1 ATOM 4726 C C . ASN B 1 184 ? 127.464 -22.556 50.879 1.00 12.85 ? 186 ASN B C 1 ATOM 4727 O O . ASN B 1 184 ? 127.001 -22.020 49.870 1.00 12.64 ? 186 ASN B O 1 ATOM 4728 C CB . ASN B 1 184 ? 125.767 -23.360 52.558 1.00 11.97 ? 186 ASN B CB 1 ATOM 4729 C CG . ASN B 1 184 ? 126.344 -24.626 53.170 1.00 11.61 ? 186 ASN B CG 1 ATOM 4730 O OD1 . ASN B 1 184 ? 127.556 -24.831 53.161 1.00 12.53 ? 186 ASN B OD1 1 ATOM 4731 N ND2 . ASN B 1 184 ? 125.475 -25.502 53.666 1.00 11.47 ? 186 ASN B ND2 1 ATOM 4732 N N . ILE B 1 185 ? 128.560 -23.306 50.866 1.00 13.21 ? 187 ILE B N 1 ATOM 4733 C CA . ILE B 1 185 ? 129.246 -23.658 49.633 1.00 14.24 ? 187 ILE B CA 1 ATOM 4734 C C . ILE B 1 185 ? 129.218 -25.172 49.485 1.00 14.03 ? 187 ILE B C 1 ATOM 4735 O O . ILE B 1 185 ? 129.638 -25.894 50.390 1.00 14.21 ? 187 ILE B O 1 ATOM 4736 C CB . ILE B 1 185 ? 130.711 -23.180 49.652 1.00 14.83 ? 187 ILE B CB 1 ATOM 4737 C CG1 . ILE B 1 185 ? 130.774 -21.663 49.856 1.00 15.23 ? 187 ILE B CG1 1 ATOM 4738 C CG2 . ILE B 1 185 ? 131.425 -23.592 48.371 1.00 14.82 ? 187 ILE B CG2 1 ATOM 4739 C CD1 . ILE B 1 185 ? 132.061 -21.180 50.492 1.00 14.87 ? 187 ILE B CD1 1 ATOM 4740 N N . VAL B 1 186 ? 128.680 -25.650 48.367 1.00 12.98 ? 188 VAL B N 1 ATOM 4741 C CA . VAL B 1 186 ? 128.386 -27.069 48.216 1.00 13.18 ? 188 VAL B CA 1 ATOM 4742 C C . VAL B 1 186 ? 128.879 -27.603 46.875 1.00 13.14 ? 188 VAL B C 1 ATOM 4743 O O . VAL B 1 186 ? 129.042 -26.849 45.919 1.00 13.62 ? 188 VAL B O 1 ATOM 4744 C CB . VAL B 1 186 ? 126.876 -27.353 48.365 1.00 12.76 ? 188 VAL B CB 1 ATOM 4745 C CG1 . VAL B 1 186 ? 126.332 -26.675 49.615 1.00 12.47 ? 188 VAL B CG1 1 ATOM 4746 C CG2 . VAL B 1 186 ? 126.115 -26.887 47.131 1.00 12.11 ? 188 VAL B CG2 1 ATOM 4747 N N . ASP B 1 187 ? 129.115 -28.909 46.814 1.00 14.12 ? 189 ASP B N 1 ATOM 4748 C CA . ASP B 1 187 ? 129.425 -29.571 45.552 1.00 14.52 ? 189 ASP B CA 1 ATOM 4749 C C . ASP B 1 187 ? 128.259 -29.454 44.575 1.00 13.23 ? 189 ASP B C 1 ATOM 4750 O O . ASP B 1 187 ? 127.093 -29.533 44.969 1.00 13.43 ? 189 ASP B O 1 ATOM 4751 C CB . ASP B 1 187 ? 129.762 -31.043 45.792 1.00 15.36 ? 189 ASP B CB 1 ATOM 4752 C CG . ASP B 1 187 ? 130.999 -31.224 46.653 1.00 17.89 ? 189 ASP B CG 1 ATOM 4753 O OD1 . ASP B 1 187 ? 131.979 -30.476 46.452 1.00 19.14 ? 189 ASP B OD1 1 ATOM 4754 O OD2 . ASP B 1 187 ? 130.992 -32.118 47.527 1.00 19.17 ? 189 ASP B OD2 1 ATOM 4755 N N . ALA B 1 188 ? 128.577 -29.262 43.300 1.00 12.46 ? 190 ALA B N 1 ATOM 4756 C CA . ALA B 1 188 ? 127.557 -29.143 42.266 1.00 11.47 ? 190 ALA B CA 1 ATOM 4757 C C . ALA B 1 188 ? 126.576 -30.313 42.327 1.00 11.56 ? 190 ALA B C 1 ATOM 4758 O O . ALA B 1 188 ? 125.383 -30.153 42.057 1.00 10.96 ? 190 ALA B O 1 ATOM 4759 C CB . ALA B 1 188 ? 128.208 -29.071 40.893 1.00 11.28 ? 190 ALA B CB 1 ATOM 4760 N N . GLY B 1 189 ? 127.081 -31.484 42.703 1.00 11.03 ? 191 GLY B N 1 ATOM 4761 C CA . GLY B 1 189 ? 126.295 -32.708 42.659 1.00 10.31 ? 191 GLY B CA 1 ATOM 4762 C C . GLY B 1 189 ? 125.180 -32.752 43.686 1.00 10.39 ? 191 GLY B C 1 ATOM 4763 O O . GLY B 1 189 ? 124.329 -33.639 43.651 1.00 9.73 ? 191 GLY B O 1 ATOM 4764 N N . VAL B 1 190 ? 125.190 -31.807 44.618 1.00 10.45 ? 192 VAL B N 1 ATOM 4765 C CA . VAL B 1 190 ? 124.077 -31.660 45.545 1.00 9.83 ? 192 VAL B CA 1 ATOM 4766 C C . VAL B 1 190 ? 122.810 -31.198 44.823 1.00 9.73 ? 192 VAL B C 1 ATOM 4767 O O . VAL B 1 190 ? 121.706 -31.590 45.185 1.00 9.62 ? 192 VAL B O 1 ATOM 4768 C CB . VAL B 1 190 ? 124.417 -30.691 46.693 1.00 10.41 ? 192 VAL B CB 1 ATOM 4769 C CG1 . VAL B 1 190 ? 123.202 -30.476 47.586 1.00 9.23 ? 192 VAL B CG1 1 ATOM 4770 C CG2 . VAL B 1 190 ? 125.591 -31.231 47.497 1.00 10.46 ? 192 VAL B CG2 1 ATOM 4771 N N . ILE B 1 191 ? 122.984 -30.410 43.766 1.00 9.23 ? 193 ILE B N 1 ATOM 4772 C CA . ILE B 1 191 ? 121.854 -29.846 43.035 1.00 9.39 ? 193 ILE B CA 1 ATOM 4773 C C . ILE B 1 191 ? 121.715 -30.461 41.644 1.00 9.83 ? 193 ILE B C 1 ATOM 4774 O O . ILE B 1 191 ? 120.604 -30.686 41.162 1.00 9.45 ? 193 ILE B O 1 ATOM 4775 C CB . ILE B 1 191 ? 121.981 -28.316 42.903 1.00 9.40 ? 193 ILE B CB 1 ATOM 4776 C CG1 . ILE B 1 191 ? 122.126 -27.672 44.287 1.00 9.21 ? 193 ILE B CG1 1 ATOM 4777 C CG2 . ILE B 1 191 ? 120.790 -27.737 42.152 1.00 9.68 ? 193 ILE B CG2 1 ATOM 4778 C CD1 . ILE B 1 191 ? 120.949 -27.918 45.207 1.00 8.54 ? 193 ILE B CD1 1 ATOM 4779 N N . ILE B 1 192 ? 122.846 -30.715 40.995 1.00 9.94 ? 194 ILE B N 1 ATOM 4780 C CA . ILE B 1 192 ? 122.843 -31.172 39.607 1.00 10.32 ? 194 ILE B CA 1 ATOM 4781 C C . ILE B 1 192 ? 123.116 -32.671 39.544 1.00 10.71 ? 194 ILE B C 1 ATOM 4782 O O . ILE B 1 192 ? 124.146 -33.137 40.028 1.00 10.97 ? 194 ILE B O 1 ATOM 4783 C CB . ILE B 1 192 ? 123.916 -30.438 38.777 1.00 10.59 ? 194 ILE B CB 1 ATOM 4784 C CG1 . ILE B 1 192 ? 123.717 -28.918 38.856 1.00 10.56 ? 194 ILE B CG1 1 ATOM 4785 C CG2 . ILE B 1 192 ? 123.919 -30.931 37.336 1.00 10.17 ? 194 ILE B CG2 1 ATOM 4786 C CD1 . ILE B 1 192 ? 122.399 -28.436 38.287 1.00 10.28 ? 194 ILE B CD1 1 ATOM 4787 N N . THR B 1 193 ? 122.199 -33.428 38.950 1.00 10.37 ? 195 THR B N 1 ATOM 4788 C CA . THR B 1 193 ? 122.398 -34.872 38.825 1.00 11.04 ? 195 THR B CA 1 ATOM 4789 C C . THR B 1 193 ? 123.628 -35.197 37.977 1.00 11.02 ? 195 THR B C 1 ATOM 4790 O O . THR B 1 193 ? 123.777 -34.694 36.860 1.00 10.68 ? 195 THR B O 1 ATOM 4791 C CB . THR B 1 193 ? 121.155 -35.588 38.260 1.00 10.39 ? 195 THR B CB 1 ATOM 4792 O OG1 . THR B 1 193 ? 120.780 -35.003 37.006 1.00 10.58 ? 195 THR B OG1 1 ATOM 4793 C CG2 . THR B 1 193 ? 119.992 -35.474 39.229 1.00 10.57 ? 195 THR B CG2 1 ATOM 4794 N N . GLY B 1 194 ? 124.527 -36.004 38.534 1.00 10.90 ? 196 GLY B N 1 ATOM 4795 C CA . GLY B 1 194 ? 125.719 -36.442 37.812 1.00 11.65 ? 196 GLY B CA 1 ATOM 4796 C C . GLY B 1 194 ? 126.884 -35.474 37.905 1.00 12.78 ? 196 GLY B C 1 ATOM 4797 O O . GLY B 1 194 ? 127.969 -35.744 37.395 1.00 13.58 ? 196 GLY B O 1 ATOM 4798 N N . ALA B 1 195 ? 126.669 -34.346 38.571 1.00 12.66 ? 197 ALA B N 1 ATOM 4799 C CA . ALA B 1 195 ? 127.735 -33.370 38.761 1.00 13.26 ? 197 ALA B CA 1 ATOM 4800 C C . ALA B 1 195 ? 128.639 -33.759 39.929 1.00 13.20 ? 197 ALA B C 1 ATOM 4801 O O . ALA B 1 195 ? 128.430 -34.785 40.572 1.00 13.30 ? 197 ALA B O 1 ATOM 4802 C CB . ALA B 1 195 ? 127.155 -31.979 38.965 1.00 13.01 ? 197 ALA B CB 1 ATOM 4803 N N . THR B 1 196 ? 129.647 -32.935 40.193 1.00 14.13 ? 198 THR B N 1 ATOM 4804 C CA . THR B 1 196 ? 130.694 -33.280 41.150 1.00 14.11 ? 198 THR B CA 1 ATOM 4805 C C . THR B 1 196 ? 130.146 -33.831 42.462 1.00 13.91 ? 198 THR B C 1 ATOM 4806 O O . THR B 1 196 ? 129.362 -33.171 43.147 1.00 12.89 ? 198 THR B O 1 ATOM 4807 C CB . THR B 1 196 ? 131.601 -32.073 41.448 1.00 14.53 ? 198 THR B CB 1 ATOM 4808 O OG1 . THR B 1 196 ? 132.271 -31.679 40.246 1.00 17.08 ? 198 THR B OG1 1 ATOM 4809 C CG2 . THR B 1 196 ? 132.635 -32.429 42.504 1.00 14.74 ? 198 THR B CG2 1 ATOM 4810 N N . ASN B 1 197 ? 130.551 -35.055 42.790 1.00 14.24 ? 199 ASN B N 1 ATOM 4811 C CA . ASN B 1 197 ? 130.270 -35.659 44.094 1.00 15.41 ? 199 ASN B CA 1 ATOM 4812 C C . ASN B 1 197 ? 128.812 -36.052 44.327 1.00 13.63 ? 199 ASN B C 1 ATOM 4813 O O . ASN B 1 197 ? 128.404 -36.297 45.461 1.00 13.20 ? 199 ASN B O 1 ATOM 4814 C CB . ASN B 1 197 ? 130.777 -34.772 45.235 1.00 16.40 ? 199 ASN B CB 1 ATOM 4815 C CG . ASN B 1 197 ? 132.292 -34.769 45.341 1.00 20.10 ? 199 ASN B CG 1 ATOM 4816 O OD1 . ASN B 1 197 ? 132.876 -33.939 46.039 1.00 23.08 ? 199 ASN B OD1 1 ATOM 4817 N ND2 . ASN B 1 197 ? 132.939 -35.695 44.640 1.00 20.34 ? 199 ASN B ND2 1 ATOM 4818 N N . ASP B 1 198 ? 128.037 -36.130 43.249 1.00 12.66 ? 200 ASP B N 1 ATOM 4819 C CA . ASP B 1 198 ? 126.757 -36.837 43.276 1.00 12.28 ? 200 ASP B CA 1 ATOM 4820 C C . ASP B 1 198 ? 127.029 -38.344 43.281 1.00 12.34 ? 200 ASP B C 1 ATOM 4821 O O . ASP B 1 198 ? 127.565 -38.880 42.316 1.00 12.79 ? 200 ASP B O 1 ATOM 4822 C CB . ASP B 1 198 ? 125.915 -36.443 42.054 1.00 10.65 ? 200 ASP B CB 1 ATOM 4823 C CG . ASP B 1 198 ? 124.600 -37.205 41.965 1.00 11.18 ? 200 ASP B CG 1 ATOM 4824 O OD1 . ASP B 1 198 ? 124.162 -37.771 42.991 1.00 10.03 ? 200 ASP B OD1 1 ATOM 4825 O OD2 . ASP B 1 198 ? 124.006 -37.242 40.861 1.00 9.79 ? 200 ASP B OD2 1 ATOM 4826 N N . PRO B 1 199 ? 126.715 -39.020 44.397 1.00 13.01 ? 201 PRO B N 1 ATOM 4827 C CA . PRO B 1 199 ? 127.085 -40.429 44.542 1.00 13.19 ? 201 PRO B CA 1 ATOM 4828 C C . PRO B 1 199 ? 126.154 -41.371 43.780 1.00 13.91 ? 201 PRO B C 1 ATOM 4829 O O . PRO B 1 199 ? 126.457 -42.558 43.641 1.00 15.11 ? 201 PRO B O 1 ATOM 4830 C CB . PRO B 1 199 ? 126.959 -40.666 46.046 1.00 13.64 ? 201 PRO B CB 1 ATOM 4831 C CG . PRO B 1 199 ? 125.917 -39.696 46.485 1.00 14.05 ? 201 PRO B CG 1 ATOM 4832 C CD . PRO B 1 199 ? 126.097 -38.478 45.621 1.00 13.03 ? 201 PRO B CD 1 ATOM 4833 N N . ILE B 1 200 ? 125.028 -40.850 43.298 1.00 12.49 ? 202 ILE B N 1 ATOM 4834 C CA . ILE B 1 200 ? 124.015 -41.685 42.658 1.00 12.26 ? 202 ILE B CA 1 ATOM 4835 C C . ILE B 1 200 ? 124.272 -41.804 41.154 1.00 11.71 ? 202 ILE B C 1 ATOM 4836 O O . ILE B 1 200 ? 124.458 -40.800 40.470 1.00 11.15 ? 202 ILE B O 1 ATOM 4837 C CB . ILE B 1 200 ? 122.595 -41.126 42.896 1.00 12.64 ? 202 ILE B CB 1 ATOM 4838 C CG1 . ILE B 1 200 ? 122.358 -40.862 44.388 1.00 12.83 ? 202 ILE B CG1 1 ATOM 4839 C CG2 . ILE B 1 200 ? 121.540 -42.071 42.339 1.00 11.83 ? 202 ILE B CG2 1 ATOM 4840 C CD1 . ILE B 1 200 ? 122.260 -42.115 45.231 1.00 13.42 ? 202 ILE B CD1 1 ATOM 4841 N N . THR B 1 201 ? 124.319 -43.034 40.653 1.00 11.35 ? 203 THR B N 1 ATOM 4842 C CA . THR B 1 201 ? 124.510 -43.266 39.225 1.00 10.80 ? 203 THR B CA 1 ATOM 4843 C C . THR B 1 201 ? 123.276 -42.834 38.445 1.00 10.64 ? 203 THR B C 1 ATOM 4844 O O . THR B 1 201 ? 122.143 -43.133 38.834 1.00 10.12 ? 203 THR B O 1 ATOM 4845 C CB . THR B 1 201 ? 124.822 -44.743 38.924 1.00 11.64 ? 203 THR B CB 1 ATOM 4846 O OG1 . THR B 1 201 ? 126.091 -45.086 39.490 1.00 11.72 ? 203 THR B OG1 1 ATOM 4847 C CG2 . THR B 1 201 ? 124.865 -44.991 37.419 1.00 11.24 ? 203 THR B CG2 1 ATOM 4848 N N . ARG B 1 202 ? 123.503 -42.078 37.378 1.00 9.85 ? 204 ARG B N 1 ATOM 4849 C CA . ARG B 1 202 ? 122.420 -41.597 36.531 1.00 9.56 ? 204 ARG B CA 1 ATOM 4850 C C . ARG B 1 202 ? 122.646 -42.071 35.101 1.00 9.66 ? 204 ARG B C 1 ATOM 4851 O O . ARG B 1 202 ? 123.772 -42.368 34.716 1.00 9.77 ? 204 ARG B O 1 ATOM 4852 C CB . ARG B 1 202 ? 122.370 -40.069 36.553 1.00 9.62 ? 204 ARG B CB 1 ATOM 4853 C CG . ARG B 1 202 ? 122.656 -39.452 37.912 1.00 9.94 ? 204 ARG B CG 1 ATOM 4854 C CD . ARG B 1 202 ? 121.479 -39.612 38.862 1.00 9.27 ? 204 ARG B CD 1 ATOM 4855 N NE . ARG B 1 202 ? 121.706 -38.898 40.116 1.00 9.56 ? 204 ARG B NE 1 ATOM 4856 C CZ . ARG B 1 202 ? 120.784 -38.721 41.058 1.00 10.09 ? 204 ARG B CZ 1 ATOM 4857 N NH1 . ARG B 1 202 ? 119.565 -39.216 40.895 1.00 10.61 ? 204 ARG B NH1 1 ATOM 4858 N NH2 . ARG B 1 202 ? 121.089 -38.066 42.172 1.00 9.57 ? 204 ARG B NH2 1 ATOM 4859 N N . PRO B 1 203 ? 121.575 -42.121 34.297 1.00 9.53 ? 205 PRO B N 1 ATOM 4860 C CA . PRO B 1 203 ? 121.778 -42.270 32.858 1.00 9.81 ? 205 PRO B CA 1 ATOM 4861 C C . PRO B 1 203 ? 122.619 -41.110 32.332 1.00 9.44 ? 205 PRO B C 1 ATOM 4862 O O . PRO B 1 203 ? 122.433 -39.975 32.764 1.00 9.31 ? 205 PRO B O 1 ATOM 4863 C CB . PRO B 1 203 ? 120.357 -42.189 32.286 1.00 9.67 ? 205 PRO B CB 1 ATOM 4864 C CG . PRO B 1 203 ? 119.444 -42.465 33.435 1.00 9.81 ? 205 PRO B CG 1 ATOM 4865 C CD . PRO B 1 203 ? 120.157 -41.972 34.659 1.00 9.81 ? 205 PRO B CD 1 ATOM 4866 N N . SER B 1 204 ? 123.549 -41.387 31.423 1.00 9.39 ? 206 SER B N 1 ATOM 4867 C CA . SER B 1 204 ? 124.418 -40.330 30.904 1.00 9.56 ? 206 SER B CA 1 ATOM 4868 C C . SER B 1 204 ? 123.616 -39.129 30.393 1.00 10.07 ? 206 SER B C 1 ATOM 4869 O O . SER B 1 204 ? 124.007 -37.978 30.602 1.00 11.01 ? 206 SER B O 1 ATOM 4870 C CB . SER B 1 204 ? 125.344 -40.867 29.806 1.00 9.47 ? 206 SER B CB 1 ATOM 4871 O OG . SER B 1 204 ? 124.603 -41.421 28.735 1.00 8.81 ? 206 SER B OG 1 ATOM 4872 N N . TRP B 1 205 ? 122.488 -39.390 29.736 1.00 10.06 ? 207 TRP B N 1 ATOM 4873 C CA . TRP B 1 205 ? 121.691 -38.302 29.161 1.00 10.25 ? 207 TRP B CA 1 ATOM 4874 C C . TRP B 1 205 ? 121.097 -37.383 30.230 1.00 10.43 ? 207 TRP B C 1 ATOM 4875 O O . TRP B 1 205 ? 120.713 -36.250 29.934 1.00 10.49 ? 207 TRP B O 1 ATOM 4876 C CB . TRP B 1 205 ? 120.595 -38.836 28.231 1.00 10.39 ? 207 TRP B CB 1 ATOM 4877 C CG . TRP B 1 205 ? 119.581 -39.700 28.924 1.00 10.55 ? 207 TRP B CG 1 ATOM 4878 C CD1 . TRP B 1 205 ? 119.535 -41.064 28.932 1.00 10.47 ? 207 TRP B CD1 1 ATOM 4879 C CD2 . TRP B 1 205 ? 118.466 -39.257 29.710 1.00 10.51 ? 207 TRP B CD2 1 ATOM 4880 N NE1 . TRP B 1 205 ? 118.471 -41.497 29.687 1.00 10.50 ? 207 TRP B NE1 1 ATOM 4881 C CE2 . TRP B 1 205 ? 117.793 -40.408 30.168 1.00 10.53 ? 207 TRP B CE2 1 ATOM 4882 C CE3 . TRP B 1 205 ? 117.966 -37.997 30.066 1.00 10.67 ? 207 TRP B CE3 1 ATOM 4883 C CZ2 . TRP B 1 205 ? 116.658 -40.340 30.978 1.00 10.83 ? 207 TRP B CZ2 1 ATOM 4884 C CZ3 . TRP B 1 205 ? 116.836 -37.929 30.870 1.00 10.71 ? 207 TRP B CZ3 1 ATOM 4885 C CH2 . TRP B 1 205 ? 116.196 -39.096 31.319 1.00 10.54 ? 207 TRP B CH2 1 ATOM 4886 N N . ALA B 1 206 ? 121.076 -37.851 31.477 1.00 9.64 ? 208 ALA B N 1 ATOM 4887 C CA . ALA B 1 206 ? 120.508 -37.071 32.580 1.00 9.51 ? 208 ALA B CA 1 ATOM 4888 C C . ALA B 1 206 ? 121.535 -36.243 33.358 1.00 9.59 ? 208 ALA B C 1 ATOM 4889 O O . ALA B 1 206 ? 121.171 -35.478 34.252 1.00 8.91 ? 208 ALA B O 1 ATOM 4890 C CB . ALA B 1 206 ? 119.726 -37.970 33.526 1.00 9.59 ? 208 ALA B CB 1 ATOM 4891 N N . VAL B 1 207 ? 122.811 -36.381 33.011 1.00 9.29 ? 209 VAL B N 1 ATOM 4892 C CA . VAL B 1 207 ? 123.855 -35.587 33.652 1.00 9.37 ? 209 VAL B CA 1 ATOM 4893 C C . VAL B 1 207 ? 123.722 -34.118 33.262 1.00 9.65 ? 209 VAL B C 1 ATOM 4894 O O . VAL B 1 207 ? 123.741 -33.775 32.079 1.00 9.67 ? 209 VAL B O 1 ATOM 4895 C CB . VAL B 1 207 ? 125.264 -36.084 33.277 1.00 9.43 ? 209 VAL B CB 1 ATOM 4896 C CG1 . VAL B 1 207 ? 126.327 -35.140 33.831 1.00 9.27 ? 209 VAL B CG1 1 ATOM 4897 C CG2 . VAL B 1 207 ? 125.479 -37.500 33.791 1.00 9.24 ? 209 VAL B CG2 1 ATOM 4898 N N . GLY B 1 208 ? 123.557 -33.257 34.259 1.00 9.46 ? 210 GLY B N 1 ATOM 4899 C CA . GLY B 1 208 ? 123.285 -31.847 34.005 1.00 9.71 ? 210 GLY B CA 1 ATOM 4900 C C . GLY B 1 208 ? 121.866 -31.440 34.361 1.00 10.05 ? 210 GLY B C 1 ATOM 4901 O O . GLY B 1 208 ? 121.505 -30.267 34.255 1.00 10.05 ? 210 GLY B O 1 ATOM 4902 N N . GLY B 1 209 ? 121.059 -32.408 34.784 1.00 9.40 ? 211 GLY B N 1 ATOM 4903 C CA . GLY B 1 209 ? 119.677 -32.138 35.177 1.00 9.24 ? 211 GLY B CA 1 ATOM 4904 C C . GLY B 1 209 ? 119.515 -31.901 36.669 1.00 9.53 ? 211 GLY B C 1 ATOM 4905 O O . GLY B 1 209 ? 120.499 -31.831 37.407 1.00 9.45 ? 211 GLY B O 1 ATOM 4906 N N . SER B 1 210 ? 118.268 -31.732 37.102 1.00 9.17 ? 212 SER B N 1 ATOM 4907 C CA . SER B 1 210 ? 117.943 -31.592 38.520 1.00 9.10 ? 212 SER B CA 1 ATOM 4908 C C . SER B 1 210 ? 116.490 -31.989 38.761 1.00 9.22 ? 212 SER B C 1 ATOM 4909 O O . SER B 1 210 ? 115.668 -31.922 37.850 1.00 9.07 ? 212 SER B O 1 ATOM 4910 C CB . SER B 1 210 ? 118.174 -30.154 38.990 1.00 9.03 ? 212 SER B CB 1 ATOM 4911 O OG . SER B 1 210 ? 118.012 -30.050 40.394 1.00 9.24 ? 212 SER B OG 1 ATOM 4912 N N . PHE B 1 211 ? 116.174 -32.400 39.986 1.00 8.56 ? 213 PHE B N 1 ATOM 4913 C CA . PHE B 1 211 ? 114.803 -32.753 40.327 1.00 8.39 ? 213 PHE B CA 1 ATOM 4914 C C . PHE B 1 211 ? 114.055 -31.538 40.841 1.00 8.30 ? 213 PHE B C 1 ATOM 4915 O O . PHE B 1 211 ? 114.549 -30.801 41.701 1.00 8.10 ? 213 PHE B O 1 ATOM 4916 C CB . PHE B 1 211 ? 114.753 -33.874 41.368 1.00 8.05 ? 213 PHE B CB 1 ATOM 4917 C CG . PHE B 1 211 ? 115.204 -35.202 40.844 1.00 8.43 ? 213 PHE B CG 1 ATOM 4918 C CD1 . PHE B 1 211 ? 114.355 -35.980 40.066 1.00 8.50 ? 213 PHE B CD1 1 ATOM 4919 C CD2 . PHE B 1 211 ? 116.483 -35.669 41.113 1.00 8.46 ? 213 PHE B CD2 1 ATOM 4920 C CE1 . PHE B 1 211 ? 114.775 -37.199 39.569 1.00 8.42 ? 213 PHE B CE1 1 ATOM 4921 C CE2 . PHE B 1 211 ? 116.907 -36.892 40.623 1.00 8.44 ? 213 PHE B CE2 1 ATOM 4922 C CZ . PHE B 1 211 ? 116.054 -37.653 39.842 1.00 8.27 ? 213 PHE B CZ 1 ATOM 4923 N N . LEU B 1 212 ? 112.853 -31.355 40.312 1.00 8.31 ? 214 LEU B N 1 ATOM 4924 C CA . LEU B 1 212 ? 112.038 -30.187 40.588 1.00 8.26 ? 214 LEU B CA 1 ATOM 4925 C C . LEU B 1 212 ? 110.870 -30.608 41.473 1.00 8.62 ? 214 LEU B C 1 ATOM 4926 O O . LEU B 1 212 ? 110.003 -31.378 41.052 1.00 8.91 ? 214 LEU B O 1 ATOM 4927 C CB . LEU B 1 212 ? 111.520 -29.615 39.265 1.00 8.27 ? 214 LEU B CB 1 ATOM 4928 C CG . LEU B 1 212 ? 110.821 -28.256 39.241 1.00 8.27 ? 214 LEU B CG 1 ATOM 4929 C CD1 . LEU B 1 212 ? 110.457 -27.904 37.809 1.00 8.30 ? 214 LEU B CD1 1 ATOM 4930 C CD2 . LEU B 1 212 ? 109.576 -28.251 40.115 1.00 8.27 ? 214 LEU B CD2 1 ATOM 4931 N N . ALA B 1 213 ? 110.889 -30.169 42.726 1.00 8.80 ? 215 ALA B N 1 ATOM 4932 C CA . ALA B 1 213 ? 109.734 -30.356 43.596 1.00 8.72 ? 215 ALA B CA 1 ATOM 4933 C C . ALA B 1 213 ? 108.834 -29.134 43.485 1.00 8.74 ? 215 ALA B C 1 ATOM 4934 O O . ALA B 1 213 ? 109.236 -28.027 43.846 1.00 8.78 ? 215 ALA B O 1 ATOM 4935 C CB . ALA B 1 213 ? 110.175 -30.564 45.038 1.00 8.73 ? 215 ALA B CB 1 ATOM 4936 N N . PHE B 1 214 ? 107.650 -29.327 42.915 1.00 8.99 ? 216 PHE B N 1 ATOM 4937 C CA . PHE B 1 214 ? 106.653 -28.263 42.843 1.00 9.31 ? 216 PHE B CA 1 ATOM 4938 C C . PHE B 1 214 ? 105.594 -28.428 43.923 1.00 9.30 ? 216 PHE B C 1 ATOM 4939 O O . PHE B 1 214 ? 105.077 -29.524 44.132 1.00 8.99 ? 216 PHE B O 1 ATOM 4940 C CB . PHE B 1 214 ? 105.986 -28.232 41.463 1.00 9.12 ? 216 PHE B CB 1 ATOM 4941 C CG . PHE B 1 214 ? 104.957 -27.144 41.315 1.00 9.42 ? 216 PHE B CG 1 ATOM 4942 C CD1 . PHE B 1 214 ? 103.637 -27.368 41.659 1.00 9.36 ? 216 PHE B CD1 1 ATOM 4943 C CD2 . PHE B 1 214 ? 105.318 -25.889 40.852 1.00 10.21 ? 216 PHE B CD2 1 ATOM 4944 C CE1 . PHE B 1 214 ? 102.692 -26.364 41.542 1.00 9.60 ? 216 PHE B CE1 1 ATOM 4945 C CE2 . PHE B 1 214 ? 104.379 -24.877 40.737 1.00 10.11 ? 216 PHE B CE2 1 ATOM 4946 C CZ . PHE B 1 214 ? 103.062 -25.120 41.076 1.00 9.77 ? 216 PHE B CZ 1 ATOM 4947 N N . ARG B 1 215 ? 105.246 -27.320 44.572 1.00 9.61 ? 217 ARG B N 1 ATOM 4948 C CA . ARG B 1 215 ? 104.178 -27.298 45.564 1.00 9.79 ? 217 ARG B CA 1 ATOM 4949 C C . ARG B 1 215 ? 103.344 -26.032 45.391 1.00 9.31 ? 217 ARG B C 1 ATOM 4950 O O . ARG B 1 215 ? 103.884 -24.930 45.326 1.00 8.96 ? 217 ARG B O 1 ATOM 4951 C CB . ARG B 1 215 ? 104.771 -27.333 46.975 1.00 10.25 ? 217 ARG B CB 1 ATOM 4952 C CG . ARG B 1 215 ? 105.715 -28.499 47.220 1.00 10.27 ? 217 ARG B CG 1 ATOM 4953 C CD . ARG B 1 215 ? 104.964 -29.716 47.731 1.00 11.30 ? 217 ARG B CD 1 ATOM 4954 N NE . ARG B 1 215 ? 104.525 -29.535 49.112 1.00 11.57 ? 217 ARG B NE 1 ATOM 4955 C CZ . ARG B 1 215 ? 103.629 -30.302 49.722 1.00 11.91 ? 217 ARG B CZ 1 ATOM 4956 N NH1 . ARG B 1 215 ? 103.051 -31.303 49.071 1.00 12.23 ? 217 ARG B NH1 1 ATOM 4957 N NH2 . ARG B 1 215 ? 103.316 -30.069 50.991 1.00 12.49 ? 217 ARG B NH2 1 ATOM 4958 N N . GLN B 1 216 ? 102.032 -26.191 45.278 1.00 9.08 ? 218 GLN B N 1 ATOM 4959 C CA . GLN B 1 216 ? 101.148 -25.033 45.296 1.00 9.45 ? 218 GLN B CA 1 ATOM 4960 C C . GLN B 1 216 ? 100.714 -24.751 46.725 1.00 9.38 ? 218 GLN B C 1 ATOM 4961 O O . GLN B 1 216 ? 99.890 -25.470 47.288 1.00 9.67 ? 218 GLN B O 1 ATOM 4962 C CB . GLN B 1 216 ? 99.931 -25.259 44.406 1.00 9.50 ? 218 GLN B CB 1 ATOM 4963 C CG . GLN B 1 216 ? 98.953 -24.097 44.404 1.00 10.44 ? 218 GLN B CG 1 ATOM 4964 C CD . GLN B 1 216 ? 97.863 -24.270 43.369 1.00 11.12 ? 218 GLN B CD 1 ATOM 4965 O OE1 . GLN B 1 216 ? 98.079 -24.890 42.329 1.00 11.33 ? 218 GLN B OE1 1 ATOM 4966 N NE2 . GLN B 1 216 ? 96.678 -23.736 43.655 1.00 11.44 ? 218 GLN B NE2 1 ATOM 4967 N N . LEU B 1 217 ? 101.326 -23.743 47.331 1.00 9.71 ? 219 LEU B N 1 ATOM 4968 C CA . LEU B 1 217 ? 101.135 -23.488 48.749 1.00 10.13 ? 219 LEU B CA 1 ATOM 4969 C C . LEU B 1 217 ? 100.285 -22.241 48.963 1.00 10.94 ? 219 LEU B C 1 ATOM 4970 O O . LEU B 1 217 ? 100.772 -21.119 48.837 1.00 10.98 ? 219 LEU B O 1 ATOM 4971 C CB . LEU B 1 217 ? 102.489 -23.344 49.447 1.00 10.48 ? 219 LEU B CB 1 ATOM 4972 C CG . LEU B 1 217 ? 103.437 -24.538 49.280 1.00 10.19 ? 219 LEU B CG 1 ATOM 4973 C CD1 . LEU B 1 217 ? 104.749 -24.303 50.015 1.00 10.40 ? 219 LEU B CD1 1 ATOM 4974 C CD2 . LEU B 1 217 ? 102.770 -25.820 49.750 1.00 10.34 ? 219 LEU B CD2 1 ATOM 4975 N N . GLU B 1 218 ? 99.007 -22.442 49.259 1.00 11.98 ? 220 GLU B N 1 ATOM 4976 C CA . GLU B 1 218 ? 98.124 -21.324 49.557 1.00 12.17 ? 220 GLU B CA 1 ATOM 4977 C C . GLU B 1 218 ? 98.533 -20.662 50.867 1.00 12.86 ? 220 GLU B C 1 ATOM 4978 O O . GLU B 1 218 ? 98.848 -21.340 51.845 1.00 12.76 ? 220 GLU B O 1 ATOM 4979 C CB . GLU B 1 218 ? 96.664 -21.775 49.639 1.00 14.28 ? 220 GLU B CB 1 ATOM 4980 C CG . GLU B 1 218 ? 95.738 -20.683 50.160 1.00 15.18 ? 220 GLU B CG 1 ATOM 4981 C CD . GLU B 1 218 ? 94.268 -21.050 50.090 1.00 17.74 ? 220 GLU B CD 1 ATOM 4982 O OE1 . GLU B 1 218 ? 93.949 -22.252 50.008 1.00 19.30 ? 220 GLU B OE1 1 ATOM 4983 O OE2 . GLU B 1 218 ? 93.429 -20.127 50.127 1.00 19.16 ? 220 GLU B OE2 1 ATOM 4984 N N . GLN B 1 219 ? 98.503 -19.335 50.884 1.00 13.12 ? 221 GLN B N 1 ATOM 4985 C CA . GLN B 1 219 ? 98.839 -18.576 52.082 1.00 13.66 ? 221 GLN B CA 1 ATOM 4986 C C . GLN B 1 219 ? 97.638 -17.781 52.576 1.00 13.92 ? 221 GLN B C 1 ATOM 4987 O O . GLN B 1 219 ? 97.032 -17.014 51.824 1.00 12.92 ? 221 GLN B O 1 ATOM 4988 C CB . GLN B 1 219 ? 100.007 -17.630 51.805 1.00 13.36 ? 221 GLN B CB 1 ATOM 4989 C CG . GLN B 1 219 ? 101.335 -18.339 51.609 1.00 13.95 ? 221 GLN B CG 1 ATOM 4990 C CD . GLN B 1 219 ? 102.426 -17.406 51.131 1.00 14.31 ? 221 GLN B CD 1 ATOM 4991 O OE1 . GLN B 1 219 ? 102.701 -17.316 49.933 1.00 15.35 ? 221 GLN B OE1 1 ATOM 4992 N NE2 . GLN B 1 219 ? 103.040 -16.687 52.063 1.00 14.76 ? 221 GLN B NE2 1 ATOM 4993 N N . LEU B 1 220 ? 97.314 -17.955 53.852 1.00 13.82 ? 222 LEU B N 1 ATOM 4994 C CA . LEU B 1 220 ? 96.199 -17.250 54.464 1.00 14.23 ? 222 LEU B CA 1 ATOM 4995 C C . LEU B 1 220 ? 96.691 -15.979 55.148 1.00 13.88 ? 222 LEU B C 1 ATOM 4996 O O . LEU B 1 220 ? 96.988 -15.981 56.344 1.00 14.21 ? 222 LEU B O 1 ATOM 4997 C CB . LEU B 1 220 ? 95.496 -18.158 55.475 1.00 14.06 ? 222 LEU B CB 1 ATOM 4998 C CG . LEU B 1 220 ? 95.013 -19.508 54.935 1.00 14.60 ? 222 LEU B CG 1 ATOM 4999 C CD1 . LEU B 1 220 ? 94.543 -20.407 56.069 1.00 15.50 ? 222 LEU B CD1 1 ATOM 5000 C CD2 . LEU B 1 220 ? 93.901 -19.303 53.916 1.00 14.99 ? 222 LEU B CD2 1 ATOM 5001 N N . VAL B 1 221 ? 96.765 -14.893 54.386 1.00 13.33 ? 223 VAL B N 1 ATOM 5002 C CA . VAL B 1 221 ? 97.545 -13.728 54.794 1.00 13.48 ? 223 VAL B CA 1 ATOM 5003 C C . VAL B 1 221 ? 96.844 -12.889 55.866 1.00 14.38 ? 223 VAL B C 1 ATOM 5004 O O . VAL B 1 221 ? 97.452 -12.548 56.884 1.00 15.01 ? 223 VAL B O 1 ATOM 5005 C CB . VAL B 1 221 ? 97.943 -12.857 53.582 1.00 12.90 ? 223 VAL B CB 1 ATOM 5006 C CG1 . VAL B 1 221 ? 98.700 -11.617 54.034 1.00 13.12 ? 223 VAL B CG1 1 ATOM 5007 C CG2 . VAL B 1 221 ? 98.777 -13.669 52.599 1.00 12.40 ? 223 VAL B CG2 1 ATOM 5008 N N . PRO B 1 222 ? 95.551 -12.585 55.664 1.00 14.99 ? 224 PRO B N 1 ATOM 5009 C CA . PRO B 1 222 ? 94.789 -11.883 56.698 1.00 15.10 ? 224 PRO B CA 1 ATOM 5010 C C . PRO B 1 222 ? 94.769 -12.657 58.013 1.00 16.11 ? 224 PRO B C 1 ATOM 5011 O O . PRO B 1 222 ? 94.907 -12.064 59.087 1.00 15.06 ? 224 PRO B O 1 ATOM 5012 C CB . PRO B 1 222 ? 93.378 -11.813 56.105 1.00 15.32 ? 224 PRO B CB 1 ATOM 5013 C CG . PRO B 1 222 ? 93.598 -11.829 54.632 1.00 13.96 ? 224 PRO B CG 1 ATOM 5014 C CD . PRO B 1 222 ? 94.791 -12.717 54.409 1.00 14.07 ? 224 PRO B CD 1 ATOM 5015 N N . GLU B 1 223 ? 94.616 -13.974 57.917 1.00 16.11 ? 225 GLU B N 1 ATOM 5016 C CA . GLU B 1 223 ? 94.619 -14.840 59.088 1.00 15.71 ? 225 GLU B CA 1 ATOM 5017 C C . GLU B 1 223 ? 95.966 -14.807 59.812 1.00 16.58 ? 225 GLU B C 1 ATOM 5018 O O . GLU B 1 223 ? 96.022 -14.667 61.035 1.00 15.99 ? 225 GLU B O 1 ATOM 5019 C CB . GLU B 1 223 ? 94.252 -16.273 58.689 1.00 15.36 ? 225 GLU B CB 1 ATOM 5020 C CG . GLU B 1 223 ? 92.793 -16.455 58.291 1.00 15.81 ? 225 GLU B CG 1 ATOM 5021 C CD . GLU B 1 223 ? 92.535 -16.181 56.817 1.00 15.88 ? 225 GLU B CD 1 ATOM 5022 O OE1 . GLU B 1 223 ? 93.402 -15.570 56.152 1.00 15.21 ? 225 GLU B OE1 1 ATOM 5023 O OE2 . GLU B 1 223 ? 91.450 -16.562 56.326 1.00 15.48 ? 225 GLU B OE2 1 ATOM 5024 N N . PHE B 1 224 ? 97.046 -14.925 59.046 1.00 15.97 ? 226 PHE B N 1 ATOM 5025 C CA . PHE B 1 224 ? 98.404 -14.734 59.559 1.00 16.56 ? 226 PHE B CA 1 ATOM 5026 C C . PHE B 1 224 ? 98.527 -13.424 60.333 1.00 17.13 ? 226 PHE B C 1 ATOM 5027 O O . PHE B 1 224 ? 98.953 -13.412 61.491 1.00 16.38 ? 226 PHE B O 1 ATOM 5028 C CB . PHE B 1 224 ? 99.404 -14.762 58.397 1.00 17.18 ? 226 PHE B CB 1 ATOM 5029 C CG . PHE B 1 224 ? 100.838 -14.558 58.808 1.00 17.86 ? 226 PHE B CG 1 ATOM 5030 C CD1 . PHE B 1 224 ? 101.526 -15.549 59.491 1.00 19.15 ? 226 PHE B CD1 1 ATOM 5031 C CD2 . PHE B 1 224 ? 101.530 -13.427 58.406 1.00 18.03 ? 226 PHE B CD2 1 ATOM 5032 C CE1 . PHE B 1 224 ? 102.860 -15.387 59.821 1.00 19.22 ? 226 PHE B CE1 1 ATOM 5033 C CE2 . PHE B 1 224 ? 102.863 -13.258 58.730 1.00 19.55 ? 226 PHE B CE2 1 ATOM 5034 C CZ . PHE B 1 224 ? 103.530 -14.241 59.439 1.00 18.55 ? 226 PHE B CZ 1 ATOM 5035 N N . ASN B 1 225 ? 98.124 -12.327 59.698 1.00 17.49 ? 227 ASN B N 1 ATOM 5036 C CA . ASN B 1 225 ? 98.282 -10.993 60.274 1.00 18.27 ? 227 ASN B CA 1 ATOM 5037 C C . ASN B 1 225 ? 97.515 -10.817 61.582 1.00 19.17 ? 227 ASN B C 1 ATOM 5038 O O . ASN B 1 225 ? 98.004 -10.185 62.520 1.00 19.16 ? 227 ASN B O 1 ATOM 5039 C CB . ASN B 1 225 ? 97.836 -9.924 59.273 1.00 18.37 ? 227 ASN B CB 1 ATOM 5040 C CG . ASN B 1 225 ? 98.674 -9.921 58.011 1.00 19.53 ? 227 ASN B CG 1 ATOM 5041 O OD1 . ASN B 1 225 ? 99.834 -10.333 58.020 1.00 20.31 ? 227 ASN B OD1 1 ATOM 5042 N ND2 . ASN B 1 225 ? 98.094 -9.435 56.919 1.00 20.08 ? 227 ASN B ND2 1 ATOM 5043 N N . LYS B 1 226 ? 96.296 -11.348 61.623 1.00 19.57 ? 228 LYS B N 1 ATOM 5044 C CA . LYS B 1 226 ? 95.469 -11.272 62.820 1.00 20.79 ? 228 LYS B CA 1 ATOM 5045 C C . LYS B 1 226 ? 96.084 -12.081 63.958 1.00 21.43 ? 228 LYS B C 1 ATOM 5046 O O . LYS B 1 226 ? 96.142 -11.617 65.096 1.00 21.25 ? 228 LYS B O 1 ATOM 5047 C CB . LYS B 1 226 ? 94.050 -11.763 62.524 1.00 22.74 ? 228 LYS B CB 1 ATOM 5048 C CG . LYS B 1 226 ? 93.146 -11.836 63.746 1.00 26.43 ? 228 LYS B CG 1 ATOM 5049 C CD . LYS B 1 226 ? 91.921 -12.696 63.478 1.00 30.44 ? 228 LYS B CD 1 ATOM 5050 C CE . LYS B 1 226 ? 91.207 -13.068 64.770 1.00 34.10 ? 228 LYS B CE 1 ATOM 5051 N NZ . LYS B 1 226 ? 90.942 -11.874 65.621 1.00 35.19 ? 228 LYS B NZ 1 ATOM 5052 N N . TYR B 1 227 ? 96.562 -13.282 63.644 1.00 21.02 ? 229 TYR B N 1 ATOM 5053 C CA . TYR B 1 227 ? 97.189 -14.132 64.652 1.00 21.41 ? 229 TYR B CA 1 ATOM 5054 C C . TYR B 1 227 ? 98.346 -13.416 65.342 1.00 21.20 ? 229 TYR B C 1 ATOM 5055 O O . TYR B 1 227 ? 98.485 -13.478 66.566 1.00 22.63 ? 229 TYR B O 1 ATOM 5056 C CB . TYR B 1 227 ? 97.677 -15.452 64.048 1.00 20.75 ? 229 TYR B CB 1 ATOM 5057 C CG . TYR B 1 227 ? 98.212 -16.410 65.089 1.00 21.25 ? 229 TYR B CG 1 ATOM 5058 C CD1 . TYR B 1 227 ? 99.539 -16.356 65.497 1.00 20.79 ? 229 TYR B CD1 1 ATOM 5059 C CD2 . TYR B 1 227 ? 97.371 -17.316 65.719 1.00 21.31 ? 229 TYR B CD2 1 ATOM 5060 C CE1 . TYR B 1 227 ? 100.017 -17.198 66.487 1.00 20.66 ? 229 TYR B CE1 1 ATOM 5061 C CE2 . TYR B 1 227 ? 97.841 -18.169 66.701 1.00 21.73 ? 229 TYR B CE2 1 ATOM 5062 C CZ . TYR B 1 227 ? 99.162 -18.106 67.081 1.00 21.72 ? 229 TYR B CZ 1 ATOM 5063 O OH . TYR B 1 227 ? 99.622 -18.948 68.070 1.00 21.12 ? 229 TYR B OH 1 ATOM 5064 N N . LEU B 1 228 ? 99.178 -12.744 64.553 1.00 19.74 ? 230 LEU B N 1 ATOM 5065 C CA . LEU B 1 228 ? 100.303 -11.994 65.098 1.00 19.63 ? 230 LEU B CA 1 ATOM 5066 C C . LEU B 1 228 ? 99.810 -10.920 66.063 1.00 20.54 ? 230 LEU B C 1 ATOM 5067 O O . LEU B 1 228 ? 100.349 -10.762 67.159 1.00 19.37 ? 230 LEU B O 1 ATOM 5068 C CB . LEU B 1 228 ? 101.123 -11.352 63.977 1.00 18.37 ? 230 LEU B CB 1 ATOM 5069 C CG . LEU B 1 228 ? 101.798 -12.292 62.974 1.00 18.48 ? 230 LEU B CG 1 ATOM 5070 C CD1 . LEU B 1 228 ? 102.716 -11.504 62.049 1.00 16.99 ? 230 LEU B CD1 1 ATOM 5071 C CD2 . LEU B 1 228 ? 102.571 -13.384 63.697 1.00 17.62 ? 230 LEU B CD2 1 ATOM 5072 N N . LEU B 1 229 ? 98.774 -10.195 65.651 1.00 19.62 ? 231 LEU B N 1 ATOM 5073 C CA . LEU B 1 229 ? 98.179 -9.161 66.491 1.00 20.28 ? 231 LEU B CA 1 ATOM 5074 C C . LEU B 1 229 ? 97.626 -9.751 67.783 1.00 21.62 ? 231 LEU B C 1 ATOM 5075 O O . LEU B 1 229 ? 97.787 -9.172 68.859 1.00 23.64 ? 231 LEU B O 1 ATOM 5076 C CB . LEU B 1 229 ? 97.076 -8.415 65.733 1.00 19.59 ? 231 LEU B CB 1 ATOM 5077 C CG . LEU B 1 229 ? 97.523 -7.473 64.613 1.00 19.16 ? 231 LEU B CG 1 ATOM 5078 C CD1 . LEU B 1 229 ? 96.334 -7.021 63.778 1.00 19.18 ? 231 LEU B CD1 1 ATOM 5079 C CD2 . LEU B 1 229 ? 98.279 -6.276 65.168 1.00 18.14 ? 231 LEU B CD2 1 ATOM 5080 N N . ASP B 1 230 ? 96.989 -10.912 67.673 1.00 22.24 ? 232 ASP B N 1 ATOM 5081 C CA . ASP B 1 230 ? 96.320 -11.531 68.812 1.00 22.13 ? 232 ASP B CA 1 ATOM 5082 C C . ASP B 1 230 ? 97.306 -12.152 69.794 1.00 23.43 ? 232 ASP B C 1 ATOM 5083 O O . ASP B 1 230 ? 96.989 -12.327 70.968 1.00 21.88 ? 232 ASP B O 1 ATOM 5084 C CB . ASP B 1 230 ? 95.330 -12.596 68.341 1.00 23.21 ? 232 ASP B CB 1 ATOM 5085 C CG . ASP B 1 230 ? 94.077 -12.003 67.734 1.00 24.54 ? 232 ASP B CG 1 ATOM 5086 O OD1 . ASP B 1 230 ? 93.945 -10.760 67.720 1.00 24.21 ? 232 ASP B OD1 1 ATOM 5087 O OD2 . ASP B 1 230 ? 93.223 -12.784 67.267 1.00 27.55 ? 232 ASP B OD2 1 ATOM 5088 N N . ASN B 1 231 ? 98.485 -12.526 69.304 1.00 22.59 ? 233 ASN B N 1 ATOM 5089 C CA . ASN B 1 231 ? 99.440 -13.268 70.121 1.00 22.65 ? 233 ASN B CA 1 ATOM 5090 C C . ASN B 1 231 ? 100.778 -12.557 70.285 1.00 22.82 ? 233 ASN B C 1 ATOM 5091 O O . ASN B 1 231 ? 101.761 -13.161 70.713 1.00 23.78 ? 233 ASN B O 1 ATOM 5092 C CB . ASN B 1 231 ? 99.658 -14.667 69.551 1.00 22.24 ? 233 ASN B CB 1 ATOM 5093 C CG . ASN B 1 231 ? 98.381 -15.478 69.499 1.00 23.06 ? 233 ASN B CG 1 ATOM 5094 O OD1 . ASN B 1 231 ? 97.714 -15.545 68.464 1.00 23.80 ? 233 ASN B OD1 1 ATOM 5095 N ND2 . ASN B 1 231 ? 98.035 -16.105 70.616 1.00 21.60 ? 233 ASN B ND2 1 ATOM 5096 N N . ALA B 1 232 ? 100.811 -11.274 69.945 1.00 21.32 ? 234 ALA B N 1 ATOM 5097 C CA . ALA B 1 232 ? 102.029 -10.484 70.068 1.00 22.99 ? 234 ALA B CA 1 ATOM 5098 C C . ALA B 1 232 ? 102.548 -10.527 71.503 1.00 25.53 ? 234 ALA B C 1 ATOM 5099 O O . ALA B 1 232 ? 101.764 -10.522 72.451 1.00 23.61 ? 234 ALA B O 1 ATOM 5100 C CB . ALA B 1 232 ? 101.773 -9.050 69.637 1.00 21.98 ? 234 ALA B CB 1 ATOM 5101 N N . PRO B 1 233 ? 103.877 -10.601 71.667 1.00 26.84 ? 235 PRO B N 1 ATOM 5102 C CA . PRO B 1 233 ? 104.450 -10.599 73.009 1.00 28.31 ? 235 PRO B CA 1 ATOM 5103 C C . PRO B 1 233 ? 104.159 -9.292 73.737 1.00 27.60 ? 235 PRO B C 1 ATOM 5104 O O . PRO B 1 233 ? 104.176 -8.223 73.127 1.00 25.82 ? 235 PRO B O 1 ATOM 5105 C CB . PRO B 1 233 ? 105.956 -10.744 72.755 1.00 27.74 ? 235 PRO B CB 1 ATOM 5106 C CG . PRO B 1 233 ? 106.158 -10.301 71.343 1.00 28.73 ? 235 PRO B CG 1 ATOM 5107 C CD . PRO B 1 233 ? 104.906 -10.697 70.619 1.00 27.83 ? 235 PRO B CD 1 ATOM 5108 N N . ALA B 1 234 ? 103.855 -9.386 75.027 1.00 30.95 ? 236 ALA B N 1 ATOM 5109 C CA . ALA B 1 234 ? 103.777 -8.205 75.871 1.00 29.01 ? 236 ALA B CA 1 ATOM 5110 C C . ALA B 1 234 ? 105.081 -7.430 75.766 1.00 29.76 ? 236 ALA B C 1 ATOM 5111 O O . ALA B 1 234 ? 106.164 -8.015 75.750 1.00 33.14 ? 236 ALA B O 1 ATOM 5112 C CB . ALA B 1 234 ? 103.503 -8.599 77.315 1.00 30.20 ? 236 ALA B CB 1 ATOM 5113 N N . GLY B 1 235 ? 104.975 -6.113 75.655 1.00 29.05 ? 237 GLY B N 1 ATOM 5114 C CA . GLY B 1 235 ? 106.157 -5.280 75.508 1.00 29.08 ? 237 GLY B CA 1 ATOM 5115 C C . GLY B 1 235 ? 105.810 -3.810 75.461 1.00 28.37 ? 237 GLY B C 1 ATOM 5116 O O . GLY B 1 235 ? 104.644 -3.435 75.572 1.00 29.21 ? 237 GLY B O 1 ATOM 5117 N N . SER B 1 236 ? 106.827 -2.981 75.266 1.00 31.02 ? 238 SER B N 1 ATOM 5118 C CA . SER B 1 236 ? 106.667 -1.536 75.332 1.00 31.71 ? 238 SER B CA 1 ATOM 5119 C C . SER B 1 236 ? 106.077 -0.956 74.052 1.00 31.36 ? 238 SER B C 1 ATOM 5120 O O . SER B 1 236 ? 105.360 0.043 74.089 1.00 34.98 ? 238 SER B O 1 ATOM 5121 C CB . SER B 1 236 ? 108.013 -0.873 75.627 1.00 32.25 ? 238 SER B CB 1 ATOM 5122 O OG . SER B 1 236 ? 109.010 -1.346 74.741 1.00 32.84 ? 238 SER B OG 1 ATOM 5123 N N . GLY B 1 237 ? 106.403 -1.568 72.917 1.00 31.59 ? 239 GLY B N 1 ATOM 5124 C CA . GLY B 1 237 ? 106.034 -1.010 71.618 1.00 30.05 ? 239 GLY B CA 1 ATOM 5125 C C . GLY B 1 237 ? 104.548 -1.097 71.313 1.00 30.45 ? 239 GLY B C 1 ATOM 5126 O O . GLY B 1 237 ? 103.794 -1.774 72.018 1.00 29.48 ? 239 GLY B O 1 ATOM 5127 N N . SER B 1 238 ? 104.127 -0.426 70.245 1.00 29.15 ? 240 SER B N 1 ATOM 5128 C CA . SER B 1 238 ? 102.763 -0.565 69.741 1.00 27.61 ? 240 SER B CA 1 ATOM 5129 C C . SER B 1 238 ? 102.426 -2.024 69.453 1.00 26.64 ? 240 SER B C 1 ATOM 5130 O O . SER B 1 238 ? 103.316 -2.874 69.357 1.00 24.64 ? 240 SER B O 1 ATOM 5131 C CB . SER B 1 238 ? 102.562 0.282 68.484 1.00 29.33 ? 240 SER B CB 1 ATOM 5132 O OG . SER B 1 238 ? 103.081 -0.370 67.337 1.00 31.11 ? 240 SER B OG 1 ATOM 5133 N N . LEU B 1 239 ? 101.135 -2.317 69.338 1.00 25.26 ? 241 LEU B N 1 ATOM 5134 C CA . LEU B 1 239 ? 100.694 -3.676 69.051 1.00 25.22 ? 241 LEU B CA 1 ATOM 5135 C C . LEU B 1 239 ? 101.259 -4.178 67.725 1.00 23.69 ? 241 LEU B C 1 ATOM 5136 O O . LEU B 1 239 ? 101.705 -5.319 67.629 1.00 22.91 ? 241 LEU B O 1 ATOM 5137 C CB . LEU B 1 239 ? 99.167 -3.766 69.049 1.00 24.22 ? 241 LEU B CB 1 ATOM 5138 C CG . LEU B 1 239 ? 98.587 -5.172 68.880 1.00 23.95 ? 241 LEU B CG 1 ATOM 5139 C CD1 . LEU B 1 239 ? 99.059 -6.092 69.996 1.00 24.06 ? 241 LEU B CD1 1 ATOM 5140 C CD2 . LEU B 1 239 ? 97.066 -5.128 68.819 1.00 25.43 ? 241 LEU B CD2 1 ATOM 5141 N N . GLN B 1 240 ? 101.247 -3.319 66.710 1.00 24.01 ? 242 GLN B N 1 ATOM 5142 C CA . GLN B 1 240 ? 101.681 -3.713 65.370 1.00 25.69 ? 242 GLN B CA 1 ATOM 5143 C C . GLN B 1 240 ? 103.188 -3.951 65.309 1.00 26.29 ? 242 GLN B C 1 ATOM 5144 O O . GLN B 1 240 ? 103.657 -4.838 64.592 1.00 25.06 ? 242 GLN B O 1 ATOM 5145 C CB . GLN B 1 240 ? 101.271 -2.665 64.334 1.00 24.98 ? 242 GLN B CB 1 ATOM 5146 C CG . GLN B 1 240 ? 101.607 -3.046 62.898 1.00 25.41 ? 242 GLN B CG 1 ATOM 5147 C CD . GLN B 1 240 ? 100.987 -4.366 62.481 1.00 25.97 ? 242 GLN B CD 1 ATOM 5148 O OE1 . GLN B 1 240 ? 101.692 -5.341 62.220 1.00 24.88 ? 242 GLN B OE1 1 ATOM 5149 N NE2 . GLN B 1 240 ? 99.660 -4.408 62.427 1.00 23.74 ? 242 GLN B NE2 1 ATOM 5150 N N . ALA B 1 241 ? 103.940 -3.154 66.061 1.00 25.64 ? 243 ALA B N 1 ATOM 5151 C CA . ALA B 1 241 ? 105.378 -3.363 66.201 1.00 25.54 ? 243 ALA B CA 1 ATOM 5152 C C . ALA B 1 241 ? 105.679 -4.716 66.836 1.00 24.82 ? 243 ALA B C 1 ATOM 5153 O O . ALA B 1 241 ? 106.554 -5.449 66.375 1.00 25.18 ? 243 ALA B O 1 ATOM 5154 C CB . ALA B 1 241 ? 106.000 -2.240 67.019 1.00 25.36 ? 243 ALA B CB 1 ATOM 5155 N N . ARG B 1 242 ? 104.946 -5.050 67.892 1.00 23.06 ? 244 ARG B N 1 ATOM 5156 C CA . ARG B 1 242 ? 105.157 -6.313 68.587 1.00 21.61 ? 244 ARG B CA 1 ATOM 5157 C C . ARG B 1 242 ? 104.602 -7.497 67.799 1.00 20.83 ? 244 ARG B C 1 ATOM 5158 O O . ARG B 1 242 ? 105.105 -8.615 67.905 1.00 18.94 ? 244 ARG B O 1 ATOM 5159 C CB . ARG B 1 242 ? 104.554 -6.266 69.991 1.00 21.38 ? 244 ARG B CB 1 ATOM 5160 C CG . ARG B 1 242 ? 105.223 -5.255 70.910 1.00 22.90 ? 244 ARG B CG 1 ATOM 5161 C CD . ARG B 1 242 ? 104.623 -5.288 72.306 1.00 24.18 ? 244 ARG B CD 1 ATOM 5162 N NE . ARG B 1 242 ? 103.392 -4.507 72.392 1.00 23.41 ? 244 ARG B NE 1 ATOM 5163 C CZ . ARG B 1 242 ? 102.188 -5.027 72.610 1.00 23.82 ? 244 ARG B CZ 1 ATOM 5164 N NH1 . ARG B 1 242 ? 102.041 -6.337 72.762 1.00 24.39 ? 244 ARG B NH1 1 ATOM 5165 N NH2 . ARG B 1 242 ? 101.127 -4.236 72.671 1.00 25.16 ? 244 ARG B NH2 1 ATOM 5166 N N . ALA B 1 243 ? 103.570 -7.244 66.999 1.00 20.70 ? 245 ALA B N 1 ATOM 5167 C CA . ALA B 1 243 ? 103.083 -8.242 66.053 1.00 19.76 ? 245 ALA B CA 1 ATOM 5168 C C . ALA B 1 243 ? 104.147 -8.527 64.997 1.00 18.87 ? 245 ALA B C 1 ATOM 5169 O O . ALA B 1 243 ? 104.438 -9.685 64.690 1.00 19.32 ? 245 ALA B O 1 ATOM 5170 C CB . ALA B 1 243 ? 101.789 -7.774 65.398 1.00 18.30 ? 245 ALA B CB 1 ATOM 5171 N N . ASP B 1 244 ? 104.742 -7.464 64.467 1.00 18.31 ? 246 ASP B N 1 ATOM 5172 C CA . ASP B 1 244 ? 105.821 -7.589 63.497 1.00 18.17 ? 246 ASP B CA 1 ATOM 5173 C C . ASP B 1 244 ? 106.971 -8.420 64.057 1.00 18.37 ? 246 ASP B C 1 ATOM 5174 O O . ASP B 1 244 ? 107.503 -9.299 63.378 1.00 16.90 ? 246 ASP B O 1 ATOM 5175 C CB . ASP B 1 244 ? 106.330 -6.209 63.073 1.00 18.68 ? 246 ASP B CB 1 ATOM 5176 C CG . ASP B 1 244 ? 105.332 -5.457 62.209 1.00 21.62 ? 246 ASP B CG 1 ATOM 5177 O OD1 . ASP B 1 244 ? 104.387 -6.093 61.692 1.00 22.15 ? 246 ASP B OD1 1 ATOM 5178 O OD2 . ASP B 1 244 ? 105.497 -4.230 62.041 1.00 20.91 ? 246 ASP B OD2 1 ATOM 5179 N N . LEU B 1 245 ? 107.353 -8.134 65.299 1.00 18.04 ? 247 LEU B N 1 ATOM 5180 C CA . LEU B 1 245 ? 108.418 -8.875 65.964 1.00 17.39 ? 247 LEU B CA 1 ATOM 5181 C C . LEU B 1 245 ? 108.118 -10.367 65.990 1.00 17.37 ? 247 LEU B C 1 ATOM 5182 O O . LEU B 1 245 ? 108.983 -11.187 65.668 1.00 17.98 ? 247 LEU B O 1 ATOM 5183 C CB . LEU B 1 245 ? 108.632 -8.354 67.389 1.00 16.82 ? 247 LEU B CB 1 ATOM 5184 C CG . LEU B 1 245 ? 109.625 -9.132 68.256 1.00 16.89 ? 247 LEU B CG 1 ATOM 5185 C CD1 . LEU B 1 245 ? 111.004 -9.115 67.617 1.00 17.65 ? 247 LEU B CD1 1 ATOM 5186 C CD2 . LEU B 1 245 ? 109.680 -8.556 69.665 1.00 16.56 ? 247 LEU B CD2 1 ATOM 5187 N N . LEU B 1 246 ? 106.892 -10.720 66.371 1.00 16.44 ? 248 LEU B N 1 ATOM 5188 C CA . LEU B 1 246 ? 106.494 -12.121 66.409 1.00 16.61 ? 248 LEU B CA 1 ATOM 5189 C C . LEU B 1 246 ? 106.589 -12.758 65.027 1.00 16.67 ? 248 LEU B C 1 ATOM 5190 O O . LEU B 1 246 ? 107.087 -13.874 64.884 1.00 16.45 ? 248 LEU B O 1 ATOM 5191 C CB . LEU B 1 246 ? 105.082 -12.281 66.975 1.00 16.33 ? 248 LEU B CB 1 ATOM 5192 C CG . LEU B 1 246 ? 104.570 -13.720 67.085 1.00 17.36 ? 248 LEU B CG 1 ATOM 5193 C CD1 . LEU B 1 246 ? 105.571 -14.605 67.815 1.00 17.24 ? 248 LEU B CD1 1 ATOM 5194 C CD2 . LEU B 1 246 ? 103.211 -13.766 67.768 1.00 18.95 ? 248 LEU B CD2 1 ATOM 5195 N N . GLY B 1 247 ? 106.129 -12.034 64.011 1.00 16.30 ? 249 GLY B N 1 ATOM 5196 C CA . GLY B 1 247 ? 106.235 -12.493 62.629 1.00 15.25 ? 249 GLY B CA 1 ATOM 5197 C C . GLY B 1 247 ? 107.668 -12.779 62.221 1.00 15.58 ? 249 GLY B C 1 ATOM 5198 O O . GLY B 1 247 ? 107.965 -13.824 61.637 1.00 15.76 ? 249 GLY B O 1 ATOM 5199 N N . ALA B 1 248 ? 108.559 -11.840 62.520 1.00 14.89 ? 250 ALA B N 1 ATOM 5200 C CA . ALA B 1 248 ? 109.965 -11.984 62.176 1.00 15.39 ? 250 ALA B CA 1 ATOM 5201 C C . ALA B 1 248 ? 110.614 -13.132 62.943 1.00 15.81 ? 250 ALA B C 1 ATOM 5202 O O . ALA B 1 248 ? 111.481 -13.829 62.419 1.00 15.20 ? 250 ALA B O 1 ATOM 5203 C CB . ALA B 1 248 ? 110.712 -10.680 62.419 1.00 14.27 ? 250 ALA B CB 1 ATOM 5204 N N . ARG B 1 249 ? 110.165 -13.356 64.174 1.00 16.49 ? 251 ARG B N 1 ATOM 5205 C CA . ARG B 1 249 ? 110.684 -14.461 64.963 1.00 16.54 ? 251 ARG B CA 1 ATOM 5206 C C . ARG B 1 249 ? 110.173 -15.822 64.481 1.00 16.75 ? 251 ARG B C 1 ATOM 5207 O O . ARG B 1 249 ? 110.823 -16.843 64.691 1.00 17.31 ? 251 ARG B O 1 ATOM 5208 C CB . ARG B 1 249 ? 110.424 -14.243 66.458 1.00 18.17 ? 251 ARG B CB 1 ATOM 5209 C CG . ARG B 1 249 ? 111.500 -13.386 67.113 1.00 18.71 ? 251 ARG B CG 1 ATOM 5210 C CD . ARG B 1 249 ? 111.288 -13.216 68.607 1.00 20.72 ? 251 ARG B CD 1 ATOM 5211 N NE . ARG B 1 249 ? 111.546 -14.439 69.365 1.00 20.44 ? 251 ARG B NE 1 ATOM 5212 C CZ . ARG B 1 249 ? 112.752 -14.847 69.752 1.00 18.50 ? 251 ARG B CZ 1 ATOM 5213 N NH1 . ARG B 1 249 ? 113.837 -14.180 69.381 1.00 17.65 ? 251 ARG B NH1 1 ATOM 5214 N NH2 . ARG B 1 249 ? 112.875 -15.952 70.475 1.00 19.83 ? 251 ARG B NH2 1 ATOM 5215 N N . MET B 1 250 ? 109.071 -15.815 63.739 1.00 16.12 ? 252 MET B N 1 ATOM 5216 C CA . MET B 1 250 ? 108.586 -17.028 63.094 1.00 16.57 ? 252 MET B CA 1 ATOM 5217 C C . MET B 1 250 ? 109.401 -17.373 61.856 1.00 15.11 ? 252 MET B C 1 ATOM 5218 O O . MET B 1 250 ? 109.716 -18.537 61.619 1.00 13.68 ? 252 MET B O 1 ATOM 5219 C CB . MET B 1 250 ? 107.109 -16.897 62.722 1.00 17.24 ? 252 MET B CB 1 ATOM 5220 C CG . MET B 1 250 ? 106.160 -17.211 63.864 1.00 19.63 ? 252 MET B CG 1 ATOM 5221 S SD . MET B 1 250 ? 104.445 -16.886 63.424 1.00 22.82 ? 252 MET B SD 1 ATOM 5222 C CE . MET B 1 250 ? 103.661 -16.971 65.032 1.00 22.31 ? 252 MET B CE 1 ATOM 5223 N N . VAL B 1 251 ? 109.715 -16.357 61.057 1.00 14.82 ? 253 VAL B N 1 ATOM 5224 C CA . VAL B 1 251 ? 110.432 -16.559 59.802 1.00 14.91 ? 253 VAL B CA 1 ATOM 5225 C C . VAL B 1 251 ? 111.932 -16.719 60.034 1.00 14.73 ? 253 VAL B C 1 ATOM 5226 O O . VAL B 1 251 ? 112.572 -17.585 59.435 1.00 13.31 ? 253 VAL B O 1 ATOM 5227 C CB . VAL B 1 251 ? 110.181 -15.397 58.818 1.00 14.36 ? 253 VAL B CB 1 ATOM 5228 C CG1 . VAL B 1 251 ? 111.055 -15.541 57.583 1.00 14.56 ? 253 VAL B CG1 1 ATOM 5229 C CG2 . VAL B 1 251 ? 108.710 -15.344 58.433 1.00 13.75 ? 253 VAL B CG2 1 ATOM 5230 N N . GLY B 1 252 ? 112.481 -15.897 60.926 1.00 14.78 ? 254 GLY B N 1 ATOM 5231 C CA . GLY B 1 252 ? 113.925 -15.807 61.101 1.00 13.56 ? 254 GLY B CA 1 ATOM 5232 C C . GLY B 1 252 ? 114.476 -14.559 60.443 1.00 13.26 ? 254 GLY B C 1 ATOM 5233 O O . GLY B 1 252 ? 115.676 -14.290 60.498 1.00 12.66 ? 254 GLY B O 1 ATOM 5234 N N . ARG B 1 253 ? 113.591 -13.808 59.793 1.00 13.53 ? 255 ARG B N 1 ATOM 5235 C CA . ARG B 1 253 ? 113.966 -12.557 59.146 1.00 13.39 ? 255 ARG B CA 1 ATOM 5236 C C . ARG B 1 253 ? 112.841 -11.549 59.327 1.00 13.52 ? 255 ARG B C 1 ATOM 5237 O O . ARG B 1 253 ? 111.673 -11.924 59.373 1.00 14.90 ? 255 ARG B O 1 ATOM 5238 C CB . ARG B 1 253 ? 114.200 -12.774 57.649 1.00 13.43 ? 255 ARG B CB 1 ATOM 5239 C CG . ARG B 1 253 ? 115.469 -13.536 57.300 1.00 13.52 ? 255 ARG B CG 1 ATOM 5240 C CD . ARG B 1 253 ? 115.660 -13.583 55.790 1.00 13.62 ? 255 ARG B CD 1 ATOM 5241 N NE . ARG B 1 253 ? 116.806 -14.400 55.407 1.00 13.74 ? 255 ARG B NE 1 ATOM 5242 C CZ . ARG B 1 253 ? 118.067 -13.980 55.436 1.00 13.05 ? 255 ARG B CZ 1 ATOM 5243 N NH1 . ARG B 1 253 ? 118.351 -12.739 55.814 1.00 13.24 ? 255 ARG B NH1 1 ATOM 5244 N NH2 . ARG B 1 253 ? 119.047 -14.804 55.095 1.00 12.86 ? 255 ARG B NH2 1 ATOM 5245 N N . TRP B 1 254 ? 113.197 -10.273 59.418 1.00 13.36 ? 256 TRP B N 1 ATOM 5246 C CA . TRP B 1 254 ? 112.222 -9.205 59.258 1.00 14.07 ? 256 TRP B CA 1 ATOM 5247 C C . TRP B 1 254 ? 111.735 -9.182 57.813 1.00 13.68 ? 256 TRP B C 1 ATOM 5248 O O . TRP B 1 254 ? 112.361 -9.771 56.936 1.00 13.26 ? 256 TRP B O 1 ATOM 5249 C CB . TRP B 1 254 ? 112.841 -7.858 59.642 1.00 14.95 ? 256 TRP B CB 1 ATOM 5250 C CG . TRP B 1 254 ? 113.263 -7.803 61.083 1.00 15.64 ? 256 TRP B CG 1 ATOM 5251 C CD1 . TRP B 1 254 ? 114.468 -8.187 61.599 1.00 16.08 ? 256 TRP B CD1 1 ATOM 5252 C CD2 . TRP B 1 254 ? 112.455 -7.410 62.200 1.00 17.24 ? 256 TRP B CD2 1 ATOM 5253 N NE1 . TRP B 1 254 ? 114.466 -8.037 62.968 1.00 17.80 ? 256 TRP B NE1 1 ATOM 5254 C CE2 . TRP B 1 254 ? 113.243 -7.558 63.360 1.00 16.95 ? 256 TRP B CE2 1 ATOM 5255 C CE3 . TRP B 1 254 ? 111.144 -6.940 62.332 1.00 16.55 ? 256 TRP B CE3 1 ATOM 5256 C CZ2 . TRP B 1 254 ? 112.767 -7.244 64.632 1.00 18.53 ? 256 TRP B CZ2 1 ATOM 5257 C CZ3 . TRP B 1 254 ? 110.673 -6.624 63.597 1.00 17.69 ? 256 TRP B CZ3 1 ATOM 5258 C CH2 . TRP B 1 254 ? 111.482 -6.782 64.731 1.00 18.74 ? 256 TRP B CH2 1 ATOM 5259 N N . LYS B 1 255 ? 110.614 -8.513 57.567 1.00 13.79 ? 257 LYS B N 1 ATOM 5260 C CA . LYS B 1 255 ? 110.068 -8.426 56.214 1.00 14.02 ? 257 LYS B CA 1 ATOM 5261 C C . LYS B 1 255 ? 111.040 -7.750 55.250 1.00 14.19 ? 257 LYS B C 1 ATOM 5262 O O . LYS B 1 255 ? 110.971 -7.954 54.040 1.00 15.30 ? 257 LYS B O 1 ATOM 5263 C CB . LYS B 1 255 ? 108.721 -7.698 56.223 1.00 13.54 ? 257 LYS B CB 1 ATOM 5264 C CG . LYS B 1 255 ? 107.591 -8.531 56.804 1.00 13.87 ? 257 LYS B CG 1 ATOM 5265 C CD . LYS B 1 255 ? 106.290 -7.748 56.891 1.00 14.00 ? 257 LYS B CD 1 ATOM 5266 C CE . LYS B 1 255 ? 105.140 -8.656 57.303 1.00 14.82 ? 257 LYS B CE 1 ATOM 5267 N NZ . LYS B 1 255 ? 103.881 -7.887 57.524 1.00 15.93 ? 257 LYS B NZ 1 ATOM 5268 N N . SER B 1 256 ? 111.959 -6.960 55.796 1.00 14.12 ? 258 SER B N 1 ATOM 5269 C CA . SER B 1 256 ? 112.961 -6.264 54.988 1.00 14.92 ? 258 SER B CA 1 ATOM 5270 C C . SER B 1 256 ? 114.079 -7.201 54.541 1.00 14.79 ? 258 SER B C 1 ATOM 5271 O O . SER B 1 256 ? 114.916 -6.832 53.717 1.00 16.31 ? 258 SER B O 1 ATOM 5272 C CB . SER B 1 256 ? 113.574 -5.123 55.793 1.00 16.48 ? 258 SER B CB 1 ATOM 5273 O OG . SER B 1 256 ? 114.360 -5.645 56.850 1.00 15.99 ? 258 SER B OG 1 ATOM 5274 N N . GLY B 1 257 ? 114.131 -8.387 55.136 1.00 13.86 ? 259 GLY B N 1 ATOM 5275 C CA . GLY B 1 257 ? 115.181 -9.350 54.815 1.00 13.54 ? 259 GLY B CA 1 ATOM 5276 C C . GLY B 1 257 ? 116.329 -9.351 55.809 1.00 13.93 ? 259 GLY B C 1 ATOM 5277 O O . GLY B 1 257 ? 117.231 -10.184 55.726 1.00 12.96 ? 259 GLY B O 1 ATOM 5278 N N . ALA B 1 258 ? 116.306 -8.414 56.751 1.00 13.99 ? 260 ALA B N 1 ATOM 5279 C CA . ALA B 1 258 ? 117.295 -8.411 57.824 1.00 14.60 ? 260 ALA B CA 1 ATOM 5280 C C . ALA B 1 258 ? 117.128 -9.658 58.682 1.00 14.23 ? 260 ALA B C 1 ATOM 5281 O O . ALA B 1 258 ? 116.045 -9.911 59.206 1.00 15.08 ? 260 ALA B O 1 ATOM 5282 C CB . ALA B 1 258 ? 117.157 -7.155 58.675 1.00 14.80 ? 260 ALA B CB 1 ATOM 5283 N N . PRO B 1 259 ? 118.205 -10.442 58.834 1.00 14.17 ? 261 PRO B N 1 ATOM 5284 C CA . PRO B 1 259 ? 118.137 -11.645 59.656 1.00 14.60 ? 261 PRO B CA 1 ATOM 5285 C C . PRO B 1 259 ? 118.070 -11.301 61.141 1.00 15.00 ? 261 PRO B C 1 ATOM 5286 O O . PRO B 1 259 ? 118.907 -10.555 61.642 1.00 15.59 ? 261 PRO B O 1 ATOM 5287 C CB . PRO B 1 259 ? 119.454 -12.357 59.339 1.00 14.86 ? 261 PRO B CB 1 ATOM 5288 C CG . PRO B 1 259 ? 120.391 -11.259 58.966 1.00 14.53 ? 261 PRO B CG 1 ATOM 5289 C CD . PRO B 1 259 ? 119.552 -10.214 58.282 1.00 14.26 ? 261 PRO B CD 1 ATOM 5290 N N . ILE B 1 260 ? 117.082 -11.847 61.840 1.00 16.61 ? 262 ILE B N 1 ATOM 5291 C CA . ILE B 1 260 ? 116.886 -11.510 63.247 1.00 18.72 ? 262 ILE B CA 1 ATOM 5292 C C . ILE B 1 260 ? 118.084 -11.913 64.107 1.00 18.99 ? 262 ILE B C 1 ATOM 5293 O O . ILE B 1 260 ? 118.309 -11.347 65.176 1.00 19.83 ? 262 ILE B O 1 ATOM 5294 C CB . ILE B 1 260 ? 115.590 -12.121 63.814 1.00 18.43 ? 262 ILE B CB 1 ATOM 5295 C CG1 . ILE B 1 260 ? 115.654 -13.650 63.794 1.00 18.36 ? 262 ILE B CG1 1 ATOM 5296 C CG2 . ILE B 1 260 ? 114.382 -11.623 63.036 1.00 17.77 ? 262 ILE B CG2 1 ATOM 5297 C CD1 . ILE B 1 260 ? 114.441 -14.316 64.404 1.00 19.33 ? 262 ILE B CD1 1 ATOM 5298 N N . ASP B 1 261 ? 118.879 -12.855 63.610 1.00 19.03 ? 263 ASP B N 1 ATOM 5299 C CA . ASP B 1 261 ? 120.074 -13.301 64.322 1.00 20.28 ? 263 ASP B CA 1 ATOM 5300 C C . ASP B 1 261 ? 121.104 -12.182 64.455 1.00 21.29 ? 263 ASP B C 1 ATOM 5301 O O . ASP B 1 261 ? 121.907 -12.170 65.390 1.00 21.50 ? 263 ASP B O 1 ATOM 5302 C CB . ASP B 1 261 ? 120.700 -14.505 63.615 1.00 21.46 ? 263 ASP B CB 1 ATOM 5303 C CG . ASP B 1 261 ? 121.807 -15.148 64.431 1.00 21.12 ? 263 ASP B CG 1 ATOM 5304 O OD1 . ASP B 1 261 ? 121.497 -15.755 65.477 1.00 22.28 ? 263 ASP B OD1 1 ATOM 5305 O OD2 . ASP B 1 261 ? 122.983 -15.046 64.025 1.00 21.87 ? 263 ASP B OD2 1 ATOM 5306 N N . LEU B 1 262 ? 121.072 -11.239 63.518 1.00 19.85 ? 264 LEU B N 1 ATOM 5307 C CA . LEU B 1 262 ? 121.974 -10.094 63.554 1.00 20.28 ? 264 LEU B CA 1 ATOM 5308 C C . LEU B 1 262 ? 121.294 -8.844 64.115 1.00 21.09 ? 264 LEU B C 1 ATOM 5309 O O . LEU B 1 262 ? 121.955 -7.846 64.403 1.00 21.99 ? 264 LEU B O 1 ATOM 5310 C CB . LEU B 1 262 ? 122.538 -9.807 62.161 1.00 19.38 ? 264 LEU B CB 1 ATOM 5311 C CG . LEU B 1 262 ? 123.370 -10.920 61.520 1.00 19.71 ? 264 LEU B CG 1 ATOM 5312 C CD1 . LEU B 1 262 ? 124.018 -10.430 60.233 1.00 20.08 ? 264 LEU B CD1 1 ATOM 5313 C CD2 . LEU B 1 262 ? 124.420 -11.442 62.491 1.00 20.12 ? 264 LEU B CD2 1 ATOM 5314 N N . THR B 1 263 ? 119.972 -8.898 64.257 1.00 20.53 ? 265 THR B N 1 ATOM 5315 C CA . THR B 1 263 ? 119.215 -7.768 64.787 1.00 20.56 ? 265 THR B CA 1 ATOM 5316 C C . THR B 1 263 ? 117.897 -8.222 65.406 1.00 20.95 ? 265 THR B C 1 ATOM 5317 O O . THR B 1 263 ? 116.845 -8.145 64.776 1.00 21.20 ? 265 THR B O 1 ATOM 5318 C CB . THR B 1 263 ? 118.960 -6.695 63.714 1.00 21.67 ? 265 THR B CB 1 ATOM 5319 O OG1 . THR B 1 263 ? 118.263 -5.586 64.299 1.00 24.04 ? 265 THR B OG1 1 ATOM 5320 C CG2 . THR B 1 263 ? 118.144 -7.263 62.556 1.00 20.38 ? 265 THR B CG2 1 ATOM 5321 N N . PRO B 1 264 ? 117.960 -8.696 66.658 1.00 20.72 ? 266 PRO B N 1 ATOM 5322 C CA . PRO B 1 264 ? 116.934 -9.571 67.216 1.00 20.88 ? 266 PRO B CA 1 ATOM 5323 C C . PRO B 1 264 ? 115.623 -8.875 67.574 1.00 19.23 ? 266 PRO B C 1 ATOM 5324 O O . PRO B 1 264 ? 114.590 -9.535 67.655 1.00 20.04 ? 266 PRO B O 1 ATOM 5325 C CB . PRO B 1 264 ? 117.602 -10.132 68.476 1.00 20.62 ? 266 PRO B CB 1 ATOM 5326 C CG . PRO B 1 264 ? 119.062 -10.049 68.189 1.00 20.74 ? 266 PRO B CG 1 ATOM 5327 C CD . PRO B 1 264 ? 119.217 -8.771 67.421 1.00 20.40 ? 266 PRO B CD 1 ATOM 5328 N N . THR B 1 265 ? 115.658 -7.568 67.816 1.00 19.73 ? 267 THR B N 1 ATOM 5329 C CA . THR B 1 265 ? 114.477 -6.885 68.347 1.00 20.47 ? 267 THR B CA 1 ATOM 5330 C C . THR B 1 265 ? 114.104 -5.608 67.599 1.00 21.87 ? 267 THR B C 1 ATOM 5331 O O . THR B 1 265 ? 113.126 -4.945 67.941 1.00 21.89 ? 267 THR B O 1 ATOM 5332 C CB . THR B 1 265 ? 114.605 -6.587 69.855 1.00 20.16 ? 267 THR B CB 1 ATOM 5333 O OG1 . THR B 1 265 ? 115.783 -5.809 70.098 1.00 20.18 ? 267 THR B OG1 1 ATOM 5334 C CG2 . THR B 1 265 ? 114.678 -7.881 70.651 1.00 19.96 ? 267 THR B CG2 1 ATOM 5335 N N . ALA B 1 266 ? 114.865 -5.278 66.564 1.00 21.27 ? 268 ALA B N 1 ATOM 5336 C CA . ALA B 1 266 ? 114.478 -4.199 65.667 1.00 21.64 ? 268 ALA B CA 1 ATOM 5337 C C . ALA B 1 266 ? 114.859 -4.523 64.230 1.00 22.62 ? 268 ALA B C 1 ATOM 5338 O O . ALA B 1 266 ? 115.910 -5.107 63.971 1.00 20.83 ? 268 ALA B O 1 ATOM 5339 C CB . ALA B 1 266 ? 115.112 -2.887 66.104 1.00 22.92 ? 268 ALA B CB 1 ATOM 5340 N N . ASP B 1 267 ? 114.003 -4.126 63.294 1.00 21.57 ? 269 ASP B N 1 ATOM 5341 C CA . ASP B 1 267 ? 114.311 -4.269 61.879 1.00 20.81 ? 269 ASP B CA 1 ATOM 5342 C C . ASP B 1 267 ? 115.489 -3.375 61.503 1.00 21.45 ? 269 ASP B C 1 ATOM 5343 O O . ASP B 1 267 ? 115.781 -2.398 62.191 1.00 23.00 ? 269 ASP B O 1 ATOM 5344 C CB . ASP B 1 267 ? 113.083 -3.927 61.034 1.00 20.80 ? 269 ASP B CB 1 ATOM 5345 C CG . ASP B 1 267 ? 113.317 -4.127 59.549 1.00 21.39 ? 269 ASP B CG 1 ATOM 5346 O OD1 . ASP B 1 267 ? 114.199 -4.933 59.177 1.00 18.94 ? 269 ASP B OD1 1 ATOM 5347 O OD2 . ASP B 1 267 ? 112.621 -3.463 58.756 1.00 21.37 ? 269 ASP B OD2 1 ATOM 5348 N N . ASP B 1 268 ? 116.210 -3.764 60.457 1.00 21.24 ? 270 ASP B N 1 ATOM 5349 C CA . ASP B 1 268 ? 117.317 -2.971 59.936 1.00 21.42 ? 270 ASP B CA 1 ATOM 5350 C C . ASP B 1 268 ? 117.306 -3.033 58.413 1.00 20.93 ? 270 ASP B C 1 ATOM 5351 O O . ASP B 1 268 ? 117.994 -3.862 57.816 1.00 20.18 ? 270 ASP B O 1 ATOM 5352 C CB . ASP B 1 268 ? 118.649 -3.499 60.478 1.00 22.12 ? 270 ASP B CB 1 ATOM 5353 C CG . ASP B 1 268 ? 119.834 -2.635 60.076 1.00 23.00 ? 270 ASP B CG 1 ATOM 5354 O OD1 . ASP B 1 268 ? 119.734 -1.906 59.068 1.00 23.45 ? 270 ASP B OD1 1 ATOM 5355 O OD2 . ASP B 1 268 ? 120.878 -2.704 60.760 1.00 24.45 ? 270 ASP B OD2 1 ATOM 5356 N N . PRO B 1 269 ? 116.483 -2.182 57.781 1.00 21.06 ? 271 PRO B N 1 ATOM 5357 C CA . PRO B 1 269 ? 116.232 -2.244 56.343 1.00 21.28 ? 271 PRO B CA 1 ATOM 5358 C C . PRO B 1 269 ? 117.515 -2.236 55.515 1.00 20.34 ? 271 PRO B C 1 ATOM 5359 O O . PRO B 1 269 ? 117.607 -2.940 54.510 1.00 20.42 ? 271 PRO B O 1 ATOM 5360 C CB . PRO B 1 269 ? 115.424 -0.973 56.080 1.00 21.69 ? 271 PRO B CB 1 ATOM 5361 C CG . PRO B 1 269 ? 114.693 -0.736 57.357 1.00 22.77 ? 271 PRO B CG 1 ATOM 5362 C CD . PRO B 1 269 ? 115.602 -1.212 58.458 1.00 21.70 ? 271 PRO B CD 1 ATOM 5363 N N . ALA B 1 270 ? 118.483 -1.422 55.919 1.00 20.49 ? 272 ALA B N 1 ATOM 5364 C CA . ALA B 1 270 ? 119.756 -1.344 55.213 1.00 20.00 ? 272 ALA B CA 1 ATOM 5365 C C . ALA B 1 270 ? 120.462 -2.696 55.221 1.00 19.34 ? 272 ALA B C 1 ATOM 5366 O O . ALA B 1 270 ? 120.950 -3.158 54.192 1.00 20.62 ? 272 ALA B O 1 ATOM 5367 C CB . ALA B 1 270 ? 120.645 -0.274 55.835 1.00 19.72 ? 272 ALA B CB 1 ATOM 5368 N N . LEU B 1 271 ? 120.512 -3.326 56.388 1.00 18.95 ? 273 LEU B N 1 ATOM 5369 C CA . LEU B 1 271 ? 121.050 -4.676 56.504 1.00 18.92 ? 273 LEU B CA 1 ATOM 5370 C C . LEU B 1 271 ? 120.335 -5.643 55.557 1.00 18.95 ? 273 LEU B C 1 ATOM 5371 O O . LEU B 1 271 ? 120.976 -6.365 54.792 1.00 18.96 ? 273 LEU B O 1 ATOM 5372 C CB . LEU B 1 271 ? 120.948 -5.169 57.948 1.00 18.93 ? 273 LEU B CB 1 ATOM 5373 C CG . LEU B 1 271 ? 121.366 -6.616 58.218 1.00 19.05 ? 273 LEU B CG 1 ATOM 5374 C CD1 . LEU B 1 271 ? 122.733 -6.898 57.614 1.00 19.41 ? 273 LEU B CD1 1 ATOM 5375 C CD2 . LEU B 1 271 ? 121.371 -6.894 59.714 1.00 19.50 ? 273 LEU B CD2 1 ATOM 5376 N N . GLY B 1 272 ? 119.007 -5.642 55.605 1.00 17.79 ? 274 GLY B N 1 ATOM 5377 C CA . GLY B 1 272 ? 118.208 -6.565 54.804 1.00 18.65 ? 274 GLY B CA 1 ATOM 5378 C C . GLY B 1 272 ? 118.464 -6.445 53.313 1.00 19.54 ? 274 GLY B C 1 ATOM 5379 O O . GLY B 1 272 ? 118.380 -7.429 52.579 1.00 20.32 ? 274 GLY B O 1 ATOM 5380 N N . ALA B 1 273 ? 118.779 -5.235 52.863 1.00 20.32 ? 275 ALA B N 1 ATOM 5381 C CA . ALA B 1 273 ? 118.943 -4.968 51.440 1.00 20.81 ? 275 ALA B CA 1 ATOM 5382 C C . ALA B 1 273 ? 120.361 -5.273 50.959 1.00 21.74 ? 275 ALA B C 1 ATOM 5383 O O . ALA B 1 273 ? 120.642 -5.236 49.761 1.00 22.59 ? 275 ALA B O 1 ATOM 5384 C CB . ALA B 1 273 ? 118.570 -3.528 51.126 1.00 21.80 ? 275 ALA B CB 1 ATOM 5385 N N . ASP B 1 274 ? 121.243 -5.609 51.894 1.00 19.96 ? 276 ASP B N 1 ATOM 5386 C CA . ASP B 1 274 ? 122.665 -5.726 51.597 1.00 19.56 ? 276 ASP B CA 1 ATOM 5387 C C . ASP B 1 274 ? 123.110 -7.189 51.560 1.00 18.36 ? 276 ASP B C 1 ATOM 5388 O O . ASP B 1 274 ? 123.230 -7.838 52.600 1.00 17.13 ? 276 ASP B O 1 ATOM 5389 C CB . ASP B 1 274 ? 123.480 -4.944 52.630 1.00 19.32 ? 276 ASP B CB 1 ATOM 5390 C CG . ASP B 1 274 ? 124.969 -4.959 52.338 1.00 21.04 ? 276 ASP B CG 1 ATOM 5391 O OD1 . ASP B 1 274 ? 125.399 -5.685 51.416 1.00 21.26 ? 276 ASP B OD1 1 ATOM 5392 O OD2 . ASP B 1 274 ? 125.713 -4.244 53.040 1.00 20.99 ? 276 ASP B OD2 1 ATOM 5393 N N . ALA B 1 275 ? 123.362 -7.697 50.357 1.00 18.69 ? 277 ALA B N 1 ATOM 5394 C CA . ALA B 1 275 ? 123.672 -9.114 50.167 1.00 17.90 ? 277 ALA B CA 1 ATOM 5395 C C . ALA B 1 275 ? 125.018 -9.489 50.778 1.00 18.00 ? 277 ALA B C 1 ATOM 5396 O O . ALA B 1 275 ? 125.315 -10.668 50.969 1.00 17.59 ? 277 ALA B O 1 ATOM 5397 C CB . ALA B 1 275 ? 123.643 -9.471 48.689 1.00 18.41 ? 277 ALA B CB 1 ATOM 5398 N N . GLN B 1 276 ? 125.821 -8.479 51.098 1.00 18.23 ? 278 GLN B N 1 ATOM 5399 C CA . GLN B 1 276 ? 127.129 -8.701 51.701 1.00 18.64 ? 278 GLN B CA 1 ATOM 5400 C C . GLN B 1 276 ? 127.037 -8.952 53.201 1.00 19.19 ? 278 GLN B C 1 ATOM 5401 O O . GLN B 1 276 ? 128.011 -9.372 53.823 1.00 19.62 ? 278 GLN B O 1 ATOM 5402 C CB . GLN B 1 276 ? 128.062 -7.521 51.419 1.00 19.67 ? 278 GLN B CB 1 ATOM 5403 C CG . GLN B 1 276 ? 128.590 -7.482 49.994 1.00 19.52 ? 278 GLN B CG 1 ATOM 5404 C CD . GLN B 1 276 ? 129.337 -8.747 49.619 1.00 20.22 ? 278 GLN B CD 1 ATOM 5405 O OE1 . GLN B 1 276 ? 130.224 -9.195 50.345 1.00 19.98 ? 278 GLN B OE1 1 ATOM 5406 N NE2 . GLN B 1 276 ? 128.984 -9.328 48.478 1.00 19.29 ? 278 GLN B NE2 1 ATOM 5407 N N . ARG B 1 277 ? 125.858 -8.729 53.776 1.00 18.72 ? 279 ARG B N 1 ATOM 5408 C CA . ARG B 1 277 ? 125.695 -8.829 55.222 1.00 18.85 ? 279 ARG B CA 1 ATOM 5409 C C . ARG B 1 277 ? 124.465 -9.626 55.651 1.00 18.41 ? 279 ARG B C 1 ATOM 5410 O O . ARG B 1 277 ? 124.445 -10.198 56.741 1.00 18.31 ? 279 ARG B O 1 ATOM 5411 C CB . ARG B 1 277 ? 125.669 -7.435 55.858 1.00 20.88 ? 279 ARG B CB 1 ATOM 5412 C CG . ARG B 1 277 ? 126.902 -6.602 55.556 1.00 21.73 ? 279 ARG B CG 1 ATOM 5413 C CD . ARG B 1 277 ? 127.018 -5.420 56.504 1.00 25.28 ? 279 ARG B CD 1 ATOM 5414 N NE . ARG B 1 277 ? 125.909 -4.485 56.355 1.00 22.95 ? 279 ARG B NE 1 ATOM 5415 C CZ . ARG B 1 277 ? 125.133 -4.082 57.355 1.00 26.07 ? 279 ARG B CZ 1 ATOM 5416 N NH1 . ARG B 1 277 ? 125.341 -4.533 58.585 1.00 27.04 ? 279 ARG B NH1 1 ATOM 5417 N NH2 . ARG B 1 277 ? 124.152 -3.220 57.127 1.00 25.03 ? 279 ARG B NH2 1 ATOM 5418 N N . ASN B 1 278 ? 123.442 -9.668 54.801 1.00 16.97 ? 280 ASN B N 1 ATOM 5419 C CA . ASN B 1 278 ? 122.148 -10.209 55.220 1.00 16.58 ? 280 ASN B CA 1 ATOM 5420 C C . ASN B 1 278 ? 122.110 -11.728 55.401 1.00 15.60 ? 280 ASN B C 1 ATOM 5421 O O . ASN B 1 278 ? 121.128 -12.273 55.907 1.00 15.12 ? 280 ASN B O 1 ATOM 5422 C CB . ASN B 1 278 ? 121.011 -9.729 54.309 1.00 16.13 ? 280 ASN B CB 1 ATOM 5423 C CG . ASN B 1 278 ? 121.096 -10.303 52.908 1.00 16.24 ? 280 ASN B CG 1 ATOM 5424 O OD1 . ASN B 1 278 ? 121.877 -11.215 52.641 1.00 16.07 ? 280 ASN B OD1 1 ATOM 5425 N ND2 . ASN B 1 278 ? 120.292 -9.761 52.002 1.00 16.54 ? 280 ASN B ND2 1 ATOM 5426 N N . ASN B 1 279 ? 123.196 -12.402 55.033 1.00 15.33 ? 281 ASN B N 1 ATOM 5427 C CA . ASN B 1 279 ? 123.313 -13.840 55.270 1.00 15.26 ? 281 ASN B CA 1 ATOM 5428 C C . ASN B 1 279 ? 124.531 -14.187 56.113 1.00 15.61 ? 281 ASN B C 1 ATOM 5429 O O . ASN B 1 279 ? 124.859 -15.359 56.292 1.00 14.50 ? 281 ASN B O 1 ATOM 5430 C CB . ASN B 1 279 ? 123.363 -14.609 53.946 1.00 14.14 ? 281 ASN B CB 1 ATOM 5431 C CG . ASN B 1 279 ? 122.629 -15.937 54.015 1.00 13.70 ? 281 ASN B CG 1 ATOM 5432 O OD1 . ASN B 1 279 ? 121.783 -16.151 54.888 1.00 12.85 ? 281 ASN B OD1 1 ATOM 5433 N ND2 . ASN B 1 279 ? 122.931 -16.829 53.077 1.00 13.72 ? 281 ASN B ND2 1 ATOM 5434 N N . ASN B 1 280 ? 125.190 -13.159 56.640 1.00 16.05 ? 282 ASN B N 1 ATOM 5435 C CA . ASN B 1 280 ? 126.493 -13.318 57.279 1.00 17.01 ? 282 ASN B CA 1 ATOM 5436 C C . ASN B 1 280 ? 126.396 -13.742 58.749 1.00 18.47 ? 282 ASN B C 1 ATOM 5437 O O . ASN B 1 280 ? 126.849 -13.027 59.649 1.00 17.93 ? 282 ASN B O 1 ATOM 5438 C CB . ASN B 1 280 ? 127.299 -12.025 57.130 1.00 18.26 ? 282 ASN B CB 1 ATOM 5439 C CG . ASN B 1 280 ? 128.735 -12.172 57.589 1.00 20.17 ? 282 ASN B CG 1 ATOM 5440 O OD1 . ASN B 1 280 ? 129.349 -13.225 57.423 1.00 18.64 ? 282 ASN B OD1 1 ATOM 5441 N ND2 . ASN B 1 280 ? 129.280 -11.105 58.164 1.00 22.20 ? 282 ASN B ND2 1 ATOM 5442 N N . PHE B 1 281 ? 125.809 -14.912 58.989 1.00 16.46 ? 283 PHE B N 1 ATOM 5443 C CA . PHE B 1 281 ? 125.606 -15.404 60.349 1.00 17.27 ? 283 PHE B CA 1 ATOM 5444 C C . PHE B 1 281 ? 125.596 -16.931 60.408 1.00 17.21 ? 283 PHE B C 1 ATOM 5445 O O . PHE B 1 281 ? 125.379 -17.603 59.399 1.00 15.62 ? 283 PHE B O 1 ATOM 5446 C CB . PHE B 1 281 ? 124.310 -14.838 60.944 1.00 16.88 ? 283 PHE B CB 1 ATOM 5447 C CG . PHE B 1 281 ? 123.075 -15.205 60.168 1.00 15.73 ? 283 PHE B CG 1 ATOM 5448 C CD1 . PHE B 1 281 ? 122.724 -14.504 59.025 1.00 15.70 ? 283 PHE B CD1 1 ATOM 5449 C CD2 . PHE B 1 281 ? 122.272 -16.258 60.574 1.00 15.53 ? 283 PHE B CD2 1 ATOM 5450 C CE1 . PHE B 1 281 ? 121.597 -14.850 58.301 1.00 14.64 ? 283 PHE B CE1 1 ATOM 5451 C CE2 . PHE B 1 281 ? 121.139 -16.601 59.860 1.00 14.60 ? 283 PHE B CE2 1 ATOM 5452 C CZ . PHE B 1 281 ? 120.801 -15.896 58.723 1.00 14.92 ? 283 PHE B CZ 1 ATOM 5453 N N . THR B 1 282 ? 125.834 -17.473 61.598 1.00 17.03 ? 284 THR B N 1 ATOM 5454 C CA . THR B 1 282 ? 125.889 -18.916 61.793 1.00 17.07 ? 284 THR B CA 1 ATOM 5455 C C . THR B 1 282 ? 124.892 -19.357 62.860 1.00 16.87 ? 284 THR B C 1 ATOM 5456 O O . THR B 1 282 ? 124.623 -20.548 63.015 1.00 15.26 ? 284 THR B O 1 ATOM 5457 C CB . THR B 1 282 ? 127.294 -19.364 62.234 1.00 17.37 ? 284 THR B CB 1 ATOM 5458 O OG1 . THR B 1 282 ? 127.578 -18.833 63.536 1.00 17.63 ? 284 THR B OG1 1 ATOM 5459 C CG2 . THR B 1 282 ? 128.340 -18.880 61.249 1.00 17.75 ? 284 THR B CG2 1 ATOM 5460 N N . TYR B 1 283 ? 124.328 -18.378 63.566 1.00 16.64 ? 285 TYR B N 1 ATOM 5461 C CA . TYR B 1 283 ? 123.496 -18.610 64.753 1.00 17.02 ? 285 TYR B CA 1 ATOM 5462 C C . TYR B 1 283 ? 124.310 -18.665 66.043 1.00 17.60 ? 285 TYR B C 1 ATOM 5463 O O . TYR B 1 283 ? 123.751 -18.720 67.139 1.00 17.85 ? 285 TYR B O 1 ATOM 5464 C CB . TYR B 1 283 ? 122.616 -19.855 64.609 1.00 16.80 ? 285 TYR B CB 1 ATOM 5465 C CG . TYR B 1 283 ? 121.547 -19.719 63.547 1.00 17.04 ? 285 TYR B CG 1 ATOM 5466 C CD1 . TYR B 1 283 ? 120.662 -18.645 63.555 1.00 17.10 ? 285 TYR B CD1 1 ATOM 5467 C CD2 . TYR B 1 283 ? 121.448 -20.642 62.514 1.00 16.73 ? 285 TYR B CD2 1 ATOM 5468 C CE1 . TYR B 1 283 ? 119.704 -18.501 62.567 1.00 16.79 ? 285 TYR B CE1 1 ATOM 5469 C CE2 . TYR B 1 283 ? 120.504 -20.502 61.517 1.00 16.24 ? 285 TYR B CE2 1 ATOM 5470 C CZ . TYR B 1 283 ? 119.630 -19.436 61.550 1.00 16.80 ? 285 TYR B CZ 1 ATOM 5471 O OH . TYR B 1 283 ? 118.690 -19.302 60.556 1.00 15.11 ? 285 TYR B OH 1 ATOM 5472 N N . SER B 1 284 ? 125.631 -18.629 65.910 1.00 19.18 ? 286 SER B N 1 ATOM 5473 C CA . SER B 1 284 ? 126.505 -18.603 67.076 1.00 19.93 ? 286 SER B CA 1 ATOM 5474 C C . SER B 1 284 ? 126.796 -17.171 67.511 1.00 20.28 ? 286 SER B C 1 ATOM 5475 O O . SER B 1 284 ? 126.956 -16.280 66.676 1.00 20.66 ? 286 SER B O 1 ATOM 5476 C CB . SER B 1 284 ? 127.814 -19.336 66.786 1.00 21.19 ? 286 SER B CB 1 ATOM 5477 O OG . SER B 1 284 ? 128.647 -19.336 67.931 1.00 21.62 ? 286 SER B OG 1 ATOM 5478 N N . HIS B 1 285 ? 126.859 -16.958 68.824 1.00 20.60 ? 287 HIS B N 1 ATOM 5479 C CA . HIS B 1 285 ? 127.194 -15.650 69.374 1.00 22.09 ? 287 HIS B CA 1 ATOM 5480 C C . HIS B 1 285 ? 128.093 -15.779 70.602 1.00 21.46 ? 287 HIS B C 1 ATOM 5481 O O . HIS B 1 285 ? 127.828 -16.582 71.495 1.00 21.26 ? 287 HIS B O 1 ATOM 5482 C CB . HIS B 1 285 ? 125.923 -14.878 69.740 1.00 20.60 ? 287 HIS B CB 1 ATOM 5483 C CG . HIS B 1 285 ? 124.969 -14.712 68.599 1.00 20.28 ? 287 HIS B CG 1 ATOM 5484 N ND1 . HIS B 1 285 ? 125.008 -13.628 67.748 1.00 21.43 ? 287 HIS B ND1 1 ATOM 5485 C CD2 . HIS B 1 285 ? 123.955 -15.496 68.163 1.00 20.27 ? 287 HIS B CD2 1 ATOM 5486 C CE1 . HIS B 1 285 ? 124.057 -13.750 66.840 1.00 20.35 ? 287 HIS B CE1 1 ATOM 5487 N NE2 . HIS B 1 285 ? 123.408 -14.878 67.065 1.00 20.63 ? 287 HIS B NE2 1 ATOM 5488 N N . ALA B 1 286 ? 129.157 -14.985 70.628 1.00 23.30 ? 288 ALA B N 1 ATOM 5489 C CA . ALA B 1 286 ? 129.978 -14.826 71.824 1.00 27.42 ? 288 ALA B CA 1 ATOM 5490 C C . ALA B 1 286 ? 129.314 -13.855 72.796 1.00 29.28 ? 288 ALA B C 1 ATOM 5491 O O . ALA B 1 286 ? 128.885 -12.773 72.400 1.00 33.56 ? 288 ALA B O 1 ATOM 5492 C CB . ALA B 1 286 ? 131.360 -14.321 71.442 1.00 25.31 ? 288 ALA B CB 1 ATOM 5493 N N . GLY B 1 287 ? 129.181 -14.258 74.054 1.00 33.80 ? 289 GLY B N 1 ATOM 5494 C CA . GLY B 1 287 ? 129.236 -15.659 74.440 1.00 30.06 ? 289 GLY B CA 1 ATOM 5495 C C . GLY B 1 287 ? 127.883 -16.107 74.956 1.00 30.69 ? 289 GLY B C 1 ATOM 5496 O O . GLY B 1 287 ? 127.508 -15.810 76.093 1.00 32.00 ? 289 GLY B O 1 ATOM 5497 N N . PHE B 1 288 ? 127.120 -16.761 74.088 1.00 27.45 ? 290 PHE B N 1 ATOM 5498 C CA . PHE B 1 288 ? 125.871 -17.401 74.478 1.00 26.39 ? 290 PHE B CA 1 ATOM 5499 C C . PHE B 1 288 ? 125.995 -18.907 74.294 1.00 26.05 ? 290 PHE B C 1 ATOM 5500 O O . PHE B 1 288 ? 126.791 -19.376 73.482 1.00 27.49 ? 290 PHE B O 1 ATOM 5501 C CB . PHE B 1 288 ? 124.711 -16.880 73.622 1.00 26.24 ? 290 PHE B CB 1 ATOM 5502 C CG . PHE B 1 288 ? 124.401 -15.425 73.830 1.00 24.72 ? 290 PHE B CG 1 ATOM 5503 C CD1 . PHE B 1 288 ? 125.243 -14.444 73.334 1.00 23.61 ? 290 PHE B CD1 1 ATOM 5504 C CD2 . PHE B 1 288 ? 123.233 -15.039 74.466 1.00 23.28 ? 290 PHE B CD2 1 ATOM 5505 C CE1 . PHE B 1 288 ? 124.944 -13.106 73.501 1.00 24.85 ? 290 PHE B CE1 1 ATOM 5506 C CE2 . PHE B 1 288 ? 122.929 -13.701 74.637 1.00 23.69 ? 290 PHE B CE2 1 ATOM 5507 C CZ . PHE B 1 288 ? 123.781 -12.733 74.147 1.00 22.69 ? 290 PHE B CZ 1 ATOM 5508 N N . ASP B 1 289 ? 125.189 -19.659 75.037 1.00 26.75 ? 291 ASP B N 1 ATOM 5509 C CA . ASP B 1 289 ? 125.105 -21.107 74.869 1.00 27.42 ? 291 ASP B CA 1 ATOM 5510 C C . ASP B 1 289 ? 124.233 -21.465 73.664 1.00 26.48 ? 291 ASP B C 1 ATOM 5511 O O . ASP B 1 289 ? 123.003 -21.480 73.757 1.00 25.65 ? 291 ASP B O 1 ATOM 5512 C CB . ASP B 1 289 ? 124.546 -21.751 76.141 1.00 28.53 ? 291 ASP B CB 1 ATOM 5513 C CG . ASP B 1 289 ? 124.352 -23.251 76.006 1.00 32.68 ? 291 ASP B CG 1 ATOM 5514 O OD1 . ASP B 1 289 ? 124.736 -23.819 74.963 1.00 35.41 ? 291 ASP B OD1 1 ATOM 5515 O OD2 . ASP B 1 289 ? 123.807 -23.866 76.948 1.00 37.18 ? 291 ASP B OD2 1 ATOM 5516 N N . LEU B 1 290 ? 124.878 -21.766 72.540 1.00 24.44 ? 292 LEU B N 1 ATOM 5517 C CA . LEU B 1 290 ? 124.168 -22.093 71.304 1.00 23.55 ? 292 LEU B CA 1 ATOM 5518 C C . LEU B 1 290 ? 122.993 -23.029 71.553 1.00 23.36 ? 292 LEU B C 1 ATOM 5519 O O . LEU B 1 290 ? 121.974 -22.956 70.866 1.00 24.53 ? 292 LEU B O 1 ATOM 5520 C CB . LEU B 1 290 ? 125.121 -22.718 70.280 1.00 23.19 ? 292 LEU B CB 1 ATOM 5521 C CG . LEU B 1 290 ? 124.514 -23.022 68.907 1.00 21.77 ? 292 LEU B CG 1 ATOM 5522 C CD1 . LEU B 1 290 ? 124.230 -21.734 68.155 1.00 20.06 ? 292 LEU B CD1 1 ATOM 5523 C CD2 . LEU B 1 290 ? 125.427 -23.929 68.094 1.00 23.08 ? 292 LEU B CD2 1 ATOM 5524 N N . GLY B 1 291 ? 123.135 -23.903 72.545 1.00 21.97 ? 293 GLY B N 1 ATOM 5525 C CA . GLY B 1 291 ? 122.147 -24.942 72.800 1.00 22.09 ? 293 GLY B CA 1 ATOM 5526 C C . GLY B 1 291 ? 120.910 -24.465 73.537 1.00 21.21 ? 293 GLY B C 1 ATOM 5527 O O . GLY B 1 291 ? 119.881 -25.138 73.532 1.00 21.26 ? 293 GLY B O 1 ATOM 5528 N N A SER B 1 292 ? 121.005 -23.293 74.157 0.50 22.55 ? 294 SER B N 1 ATOM 5529 N N B SER B 1 292 ? 121.014 -23.306 74.180 0.50 22.43 ? 294 SER B N 1 ATOM 5530 C CA A SER B 1 292 ? 119.956 -22.815 75.052 0.50 23.43 ? 294 SER B CA 1 ATOM 5531 C CA B SER B 1 292 ? 119.952 -22.811 75.052 0.50 23.25 ? 294 SER B CA 1 ATOM 5532 C C A SER B 1 292 ? 119.446 -21.435 74.650 0.50 23.32 ? 294 SER B C 1 ATOM 5533 C C B SER B 1 292 ? 119.415 -21.462 74.586 0.50 23.13 ? 294 SER B C 1 ATOM 5534 O O A SER B 1 292 ? 118.345 -21.036 75.032 0.50 23.99 ? 294 SER B O 1 ATOM 5535 O O B SER B 1 292 ? 118.269 -21.110 74.867 0.50 23.89 ? 294 SER B O 1 ATOM 5536 C CB A SER B 1 292 ? 120.460 -22.781 76.497 0.50 23.40 ? 294 SER B CB 1 ATOM 5537 C CB B SER B 1 292 ? 120.450 -22.695 76.495 0.50 23.09 ? 294 SER B CB 1 ATOM 5538 O OG A SER B 1 292 ? 121.569 -21.909 76.627 0.50 23.76 ? 294 SER B OG 1 ATOM 5539 O OG B SER B 1 292 ? 120.297 -23.918 77.192 0.50 23.19 ? 294 SER B OG 1 ATOM 5540 N N . ASP B 1 293 ? 120.257 -20.701 73.896 1.00 22.53 ? 295 ASP B N 1 ATOM 5541 C CA . ASP B 1 293 ? 119.950 -19.314 73.575 1.00 22.60 ? 295 ASP B CA 1 ATOM 5542 C C . ASP B 1 293 ? 119.022 -19.175 72.369 1.00 22.53 ? 295 ASP B C 1 ATOM 5543 O O . ASP B 1 293 ? 119.424 -19.417 71.231 1.00 21.67 ? 295 ASP B O 1 ATOM 5544 C CB . ASP B 1 293 ? 121.234 -18.524 73.338 1.00 22.28 ? 295 ASP B CB 1 ATOM 5545 C CG . ASP B 1 293 ? 120.967 -17.125 72.829 1.00 23.10 ? 295 ASP B CG 1 ATOM 5546 O OD1 . ASP B 1 293 ? 120.099 -16.438 73.408 1.00 24.85 ? 295 ASP B OD1 1 ATOM 5547 O OD2 . ASP B 1 293 ? 121.611 -16.719 71.838 1.00 23.93 ? 295 ASP B OD2 1 ATOM 5548 N N . GLN B 1 294 ? 117.792 -18.742 72.624 1.00 21.49 ? 296 GLN B N 1 ATOM 5549 C CA . GLN B 1 294 ? 116.858 -18.416 71.555 1.00 21.80 ? 296 GLN B CA 1 ATOM 5550 C C . GLN B 1 294 ? 116.540 -16.925 71.534 1.00 22.20 ? 296 GLN B C 1 ATOM 5551 O O . GLN B 1 294 ? 115.548 -16.501 70.941 1.00 23.05 ? 296 GLN B O 1 ATOM 5552 C CB . GLN B 1 294 ? 115.575 -19.233 71.705 1.00 21.52 ? 296 GLN B CB 1 ATOM 5553 C CG . GLN B 1 294 ? 115.817 -20.732 71.695 1.00 21.47 ? 296 GLN B CG 1 ATOM 5554 C CD . GLN B 1 294 ? 114.537 -21.538 71.652 1.00 22.68 ? 296 GLN B CD 1 ATOM 5555 O OE1 . GLN B 1 294 ? 113.867 -21.607 70.620 1.00 23.24 ? 296 GLN B OE1 1 ATOM 5556 N NE2 . GLN B 1 294 ? 114.216 -22.196 72.760 1.00 22.55 ? 296 GLN B NE2 1 ATOM 5557 N N . SER B 1 295 ? 117.394 -16.130 72.172 1.00 22.26 ? 297 SER B N 1 ATOM 5558 C CA . SER B 1 295 ? 117.156 -14.695 72.281 1.00 23.10 ? 297 SER B CA 1 ATOM 5559 C C . SER B 1 295 ? 117.444 -13.968 70.970 1.00 22.65 ? 297 SER B C 1 ATOM 5560 O O . SER B 1 295 ? 116.875 -12.911 70.701 1.00 21.92 ? 297 SER B O 1 ATOM 5561 C CB . SER B 1 295 ? 117.971 -14.089 73.428 1.00 22.74 ? 297 SER B CB 1 ATOM 5562 O OG . SER B 1 295 ? 119.277 -13.740 73.005 1.00 22.94 ? 297 SER B OG 1 ATOM 5563 N N . HIS B 1 296 ? 118.322 -14.540 70.152 1.00 21.68 ? 298 HIS B N 1 ATOM 5564 C CA . HIS B 1 296 ? 118.622 -13.973 68.842 1.00 20.87 ? 298 HIS B CA 1 ATOM 5565 C C . HIS B 1 296 ? 117.663 -14.512 67.780 1.00 19.94 ? 298 HIS B C 1 ATOM 5566 O O . HIS B 1 296 ? 117.090 -13.751 67.005 1.00 20.32 ? 298 HIS B O 1 ATOM 5567 C CB . HIS B 1 296 ? 120.068 -14.270 68.439 1.00 21.95 ? 298 HIS B CB 1 ATOM 5568 C CG . HIS B 1 296 ? 121.088 -13.716 69.386 1.00 23.52 ? 298 HIS B CG 1 ATOM 5569 N ND1 . HIS B 1 296 ? 121.421 -14.339 70.570 1.00 22.65 ? 298 HIS B ND1 1 ATOM 5570 C CD2 . HIS B 1 296 ? 121.871 -12.614 69.308 1.00 22.54 ? 298 HIS B CD2 1 ATOM 5571 C CE1 . HIS B 1 296 ? 122.352 -13.635 71.188 1.00 22.18 ? 298 HIS B CE1 1 ATOM 5572 N NE2 . HIS B 1 296 ? 122.641 -12.583 70.446 1.00 22.31 ? 298 HIS B NE2 1 ATOM 5573 N N . CYS B 1 297 ? 117.505 -15.829 67.743 1.00 19.18 ? 299 CYS B N 1 ATOM 5574 C CA . CYS B 1 297 ? 116.589 -16.470 66.800 1.00 19.86 ? 299 CYS B CA 1 ATOM 5575 C C . CYS B 1 297 ? 116.040 -17.747 67.416 1.00 19.12 ? 299 CYS B C 1 ATOM 5576 O O . CYS B 1 297 ? 116.800 -18.549 67.960 1.00 20.64 ? 299 CYS B O 1 ATOM 5577 C CB . CYS B 1 297 ? 117.307 -16.781 65.482 1.00 18.27 ? 299 CYS B CB 1 ATOM 5578 S SG . CYS B 1 297 ? 116.277 -17.563 64.212 1.00 18.21 ? 299 CYS B SG 1 ATOM 5579 N N . PRO B 1 298 ? 114.710 -17.922 67.377 1.00 17.93 ? 300 PRO B N 1 ATOM 5580 C CA . PRO B 1 298 ? 114.113 -19.150 67.887 1.00 17.79 ? 300 PRO B CA 1 ATOM 5581 C C . PRO B 1 298 ? 114.679 -20.371 67.171 1.00 17.94 ? 300 PRO B C 1 ATOM 5582 O O . PRO B 1 298 ? 115.021 -20.293 65.990 1.00 18.62 ? 300 PRO B O 1 ATOM 5583 C CB . PRO B 1 298 ? 112.628 -18.987 67.546 1.00 18.28 ? 300 PRO B CB 1 ATOM 5584 C CG . PRO B 1 298 ? 112.418 -17.515 67.452 1.00 18.09 ? 300 PRO B CG 1 ATOM 5585 C CD . PRO B 1 298 ? 113.698 -16.966 66.896 1.00 17.76 ? 300 PRO B CD 1 ATOM 5586 N N . PHE B 1 299 ? 114.758 -21.495 67.876 1.00 16.68 ? 301 PHE B N 1 ATOM 5587 C CA . PHE B 1 299 ? 115.193 -22.742 67.260 1.00 16.35 ? 301 PHE B CA 1 ATOM 5588 C C . PHE B 1 299 ? 114.181 -23.203 66.217 1.00 16.16 ? 301 PHE B C 1 ATOM 5589 O O . PHE B 1 299 ? 114.500 -24.006 65.336 1.00 15.45 ? 301 PHE B O 1 ATOM 5590 C CB . PHE B 1 299 ? 115.380 -23.825 68.321 1.00 16.71 ? 301 PHE B CB 1 ATOM 5591 C CG . PHE B 1 299 ? 116.428 -23.495 69.344 1.00 16.84 ? 301 PHE B CG 1 ATOM 5592 C CD1 . PHE B 1 299 ? 117.536 -22.740 68.999 1.00 16.85 ? 301 PHE B CD1 1 ATOM 5593 C CD2 . PHE B 1 299 ? 116.311 -23.951 70.648 1.00 18.27 ? 301 PHE B CD2 1 ATOM 5594 C CE1 . PHE B 1 299 ? 118.506 -22.437 69.938 1.00 18.14 ? 301 PHE B CE1 1 ATOM 5595 C CE2 . PHE B 1 299 ? 117.279 -23.653 71.591 1.00 18.47 ? 301 PHE B CE2 1 ATOM 5596 C CZ . PHE B 1 299 ? 118.372 -22.888 71.237 1.00 17.88 ? 301 PHE B CZ 1 ATOM 5597 N N . SER B 1 300 ? 112.965 -22.676 66.321 1.00 15.83 ? 302 SER B N 1 ATOM 5598 C CA . SER B 1 300 ? 111.837 -23.160 65.533 1.00 15.01 ? 302 SER B CA 1 ATOM 5599 C C . SER B 1 300 ? 111.575 -22.290 64.305 1.00 14.22 ? 302 SER B C 1 ATOM 5600 O O . SER B 1 300 ? 110.682 -22.588 63.513 1.00 13.54 ? 302 SER B O 1 ATOM 5601 C CB . SER B 1 300 ? 110.577 -23.219 66.399 1.00 15.02 ? 302 SER B CB 1 ATOM 5602 O OG . SER B 1 300 ? 110.378 -21.989 67.074 1.00 15.89 ? 302 SER B OG 1 ATOM 5603 N N . ALA B 1 301 ? 112.334 -21.207 64.165 1.00 13.21 ? 303 ALA B N 1 ATOM 5604 C CA . ALA B 1 301 ? 112.159 -20.282 63.046 1.00 13.74 ? 303 ALA B CA 1 ATOM 5605 C C . ALA B 1 301 ? 112.379 -20.971 61.698 1.00 13.27 ? 303 ALA B C 1 ATOM 5606 O O . ALA B 1 301 ? 113.254 -21.826 61.575 1.00 12.45 ? 303 ALA B O 1 ATOM 5607 C CB . ALA B 1 301 ? 113.097 -19.091 63.193 1.00 13.55 ? 303 ALA B CB 1 ATOM 5608 N N . HIS B 1 302 ? 111.602 -20.568 60.690 1.00 12.72 ? 304 HIS B N 1 ATOM 5609 C CA . HIS B 1 302 ? 111.627 -21.199 59.360 1.00 12.12 ? 304 HIS B CA 1 ATOM 5610 C C . HIS B 1 302 ? 113.048 -21.408 58.842 1.00 11.54 ? 304 HIS B C 1 ATOM 5611 O O . HIS B 1 302 ? 113.444 -22.538 58.555 1.00 11.61 ? 304 HIS B O 1 ATOM 5612 C CB . HIS B 1 302 ? 110.782 -20.390 58.352 1.00 12.23 ? 304 HIS B CB 1 ATOM 5613 C CG . HIS B 1 302 ? 110.810 -20.916 56.940 1.00 11.87 ? 304 HIS B CG 1 ATOM 5614 N ND1 . HIS B 1 302 ? 110.411 -22.193 56.608 1.00 12.05 ? 304 HIS B ND1 1 ATOM 5615 C CD2 . HIS B 1 302 ? 111.055 -20.286 55.763 1.00 12.28 ? 304 HIS B CD2 1 ATOM 5616 C CE1 . HIS B 1 302 ? 110.467 -22.346 55.294 1.00 11.73 ? 304 HIS B CE1 1 ATOM 5617 N NE2 . HIS B 1 302 ? 110.855 -21.202 54.755 1.00 11.88 ? 304 HIS B NE2 1 ATOM 5618 N N . ILE B 1 303 ? 113.815 -20.330 58.704 1.00 11.49 ? 305 ILE B N 1 ATOM 5619 C CA . ILE B 1 303 ? 115.116 -20.449 58.048 1.00 11.52 ? 305 ILE B CA 1 ATOM 5620 C C . ILE B 1 303 ? 116.088 -21.300 58.857 1.00 11.88 ? 305 ILE B C 1 ATOM 5621 O O . ILE B 1 303 ? 116.958 -21.962 58.299 1.00 11.65 ? 305 ILE B O 1 ATOM 5622 C CB . ILE B 1 303 ? 115.756 -19.088 57.715 1.00 11.60 ? 305 ILE B CB 1 ATOM 5623 C CG1 . ILE B 1 303 ? 115.959 -18.251 58.979 1.00 11.59 ? 305 ILE B CG1 1 ATOM 5624 C CG2 . ILE B 1 303 ? 114.933 -18.341 56.674 1.00 11.68 ? 305 ILE B CG2 1 ATOM 5625 C CD1 . ILE B 1 303 ? 116.973 -17.144 58.795 1.00 11.73 ? 305 ILE B CD1 1 ATOM 5626 N N . ARG B 1 304 ? 115.931 -21.291 60.177 1.00 12.01 ? 306 ARG B N 1 ATOM 5627 C CA . ARG B 1 304 ? 116.810 -22.066 61.044 1.00 12.97 ? 306 ARG B CA 1 ATOM 5628 C C . ARG B 1 304 ? 116.432 -23.538 60.989 1.00 12.93 ? 306 ARG B C 1 ATOM 5629 O O . ARG B 1 304 ? 117.287 -24.417 61.109 1.00 14.36 ? 306 ARG B O 1 ATOM 5630 C CB . ARG B 1 304 ? 116.732 -21.551 62.484 1.00 13.62 ? 306 ARG B CB 1 ATOM 5631 C CG . ARG B 1 304 ? 117.782 -22.144 63.411 1.00 14.19 ? 306 ARG B CG 1 ATOM 5632 C CD . ARG B 1 304 ? 117.844 -21.389 64.728 1.00 16.50 ? 306 ARG B CD 1 ATOM 5633 N NE . ARG B 1 304 ? 118.956 -21.846 65.558 1.00 17.56 ? 306 ARG B NE 1 ATOM 5634 C CZ . ARG B 1 304 ? 119.545 -21.106 66.489 1.00 17.77 ? 306 ARG B CZ 1 ATOM 5635 N NH1 . ARG B 1 304 ? 119.123 -19.870 66.719 1.00 18.89 ? 306 ARG B NH1 1 ATOM 5636 N NH2 . ARG B 1 304 ? 120.557 -21.601 67.189 1.00 18.65 ? 306 ARG B NH2 1 ATOM 5637 N N . LYS B 1 305 ? 115.141 -23.803 60.812 1.00 12.78 ? 307 LYS B N 1 ATOM 5638 C CA . LYS B 1 305 ? 114.661 -25.161 60.601 1.00 12.68 ? 307 LYS B CA 1 ATOM 5639 C C . LYS B 1 305 ? 115.146 -25.726 59.271 1.00 12.62 ? 307 LYS B C 1 ATOM 5640 O O . LYS B 1 305 ? 115.426 -26.918 59.168 1.00 13.85 ? 307 LYS B O 1 ATOM 5641 C CB . LYS B 1 305 ? 113.132 -25.210 60.660 1.00 12.58 ? 307 LYS B CB 1 ATOM 5642 C CG . LYS B 1 305 ? 112.568 -25.253 62.072 1.00 13.07 ? 307 LYS B CG 1 ATOM 5643 C CD . LYS B 1 305 ? 112.562 -26.673 62.612 1.00 14.20 ? 307 LYS B CD 1 ATOM 5644 C CE . LYS B 1 305 ? 111.470 -26.863 63.649 1.00 14.78 ? 307 LYS B CE 1 ATOM 5645 N NZ . LYS B 1 305 ? 111.335 -28.290 64.055 1.00 14.47 ? 307 LYS B NZ 1 ATOM 5646 N N . THR B 1 306 ? 115.240 -24.871 58.256 1.00 12.00 ? 308 THR B N 1 ATOM 5647 C CA . THR B 1 306 ? 115.498 -25.340 56.896 1.00 12.08 ? 308 THR B CA 1 ATOM 5648 C C . THR B 1 306 ? 116.965 -25.231 56.472 1.00 12.48 ? 308 THR B C 1 ATOM 5649 O O . THR B 1 306 ? 117.400 -25.934 55.560 1.00 12.48 ? 308 THR B O 1 ATOM 5650 C CB . THR B 1 306 ? 114.600 -24.638 55.859 1.00 11.89 ? 308 THR B CB 1 ATOM 5651 O OG1 . THR B 1 306 ? 114.740 -23.219 55.981 1.00 11.42 ? 308 THR B OG1 1 ATOM 5652 C CG2 . THR B 1 306 ? 113.135 -25.027 56.063 1.00 11.77 ? 308 THR B CG2 1 ATOM 5653 N N . ARG B 1 307 ? 117.706 -24.316 57.092 1.00 11.91 ? 309 ARG B N 1 ATOM 5654 C CA . ARG B 1 307 ? 119.167 -24.382 57.084 1.00 11.90 ? 309 ARG B CA 1 ATOM 5655 C C . ARG B 1 307 ? 119.734 -24.118 58.474 1.00 12.01 ? 309 ARG B C 1 ATOM 5656 O O . ARG B 1 307 ? 119.910 -22.967 58.870 1.00 11.28 ? 309 ARG B O 1 ATOM 5657 C CB . ARG B 1 307 ? 119.783 -23.409 56.075 1.00 11.78 ? 309 ARG B CB 1 ATOM 5658 C CG . ARG B 1 307 ? 121.271 -23.658 55.865 1.00 12.49 ? 309 ARG B CG 1 ATOM 5659 C CD . ARG B 1 307 ? 122.006 -22.475 55.254 1.00 12.64 ? 309 ARG B CD 1 ATOM 5660 N NE . ARG B 1 307 ? 123.435 -22.557 55.542 1.00 12.81 ? 309 ARG B NE 1 ATOM 5661 C CZ . ARG B 1 307 ? 124.300 -21.560 55.382 1.00 12.93 ? 309 ARG B CZ 1 ATOM 5662 N NH1 . ARG B 1 307 ? 123.900 -20.393 54.897 1.00 13.06 ? 309 ARG B NH1 1 ATOM 5663 N NH2 . ARG B 1 307 ? 125.575 -21.737 55.700 1.00 13.40 ? 309 ARG B NH2 1 ATOM 5664 N N . PRO B 1 308 ? 120.023 -25.195 59.214 1.00 12.54 ? 310 PRO B N 1 ATOM 5665 C CA . PRO B 1 308 ? 120.373 -25.148 60.636 1.00 12.83 ? 310 PRO B CA 1 ATOM 5666 C C . PRO B 1 308 ? 121.700 -24.439 60.919 1.00 13.52 ? 310 PRO B C 1 ATOM 5667 O O . PRO B 1 308 ? 121.919 -23.957 62.034 1.00 15.31 ? 310 PRO B O 1 ATOM 5668 C CB . PRO B 1 308 ? 120.471 -26.626 61.015 1.00 12.83 ? 310 PRO B CB 1 ATOM 5669 C CG . PRO B 1 308 ? 119.590 -27.323 60.033 1.00 13.76 ? 310 PRO B CG 1 ATOM 5670 C CD . PRO B 1 308 ? 119.791 -26.573 58.751 1.00 12.18 ? 310 PRO B CD 1 ATOM 5671 N N . ARG B 1 309 ? 122.578 -24.381 59.924 1.00 13.31 ? 311 ARG B N 1 ATOM 5672 C CA . ARG B 1 309 ? 123.910 -23.818 60.111 1.00 13.63 ? 311 ARG B CA 1 ATOM 5673 C C . ARG B 1 309 ? 124.612 -24.444 61.323 1.00 14.76 ? 311 ARG B C 1 ATOM 5674 O O . ARG B 1 309 ? 124.769 -25.664 61.388 1.00 14.23 ? 311 ARG B O 1 ATOM 5675 C CB . ARG B 1 309 ? 123.842 -22.288 60.203 1.00 13.23 ? 311 ARG B CB 1 ATOM 5676 C CG . ARG B 1 309 ? 123.047 -21.680 59.053 1.00 14.08 ? 311 ARG B CG 1 ATOM 5677 C CD . ARG B 1 309 ? 123.127 -20.162 58.977 1.00 14.09 ? 311 ARG B CD 1 ATOM 5678 N NE . ARG B 1 309 ? 122.136 -19.648 58.032 1.00 13.98 ? 311 ARG B NE 1 ATOM 5679 C CZ . ARG B 1 309 ? 122.321 -18.611 57.220 1.00 13.97 ? 311 ARG B CZ 1 ATOM 5680 N NH1 . ARG B 1 309 ? 123.461 -17.931 57.242 1.00 13.92 ? 311 ARG B NH1 1 ATOM 5681 N NH2 . ARG B 1 309 ? 121.360 -18.258 56.372 1.00 14.40 ? 311 ARG B NH2 1 ATOM 5682 N N . ALA B 1 310 ? 125.012 -23.623 62.288 1.00 15.28 ? 312 ALA B N 1 ATOM 5683 C CA . ALA B 1 310 ? 125.855 -24.107 63.383 1.00 15.73 ? 312 ALA B CA 1 ATOM 5684 C C . ALA B 1 310 ? 125.121 -25.058 64.327 1.00 16.53 ? 312 ALA B C 1 ATOM 5685 O O . ALA B 1 310 ? 125.751 -25.753 65.124 1.00 16.85 ? 312 ALA B O 1 ATOM 5686 C CB . ALA B 1 310 ? 126.468 -22.945 64.151 1.00 16.29 ? 312 ALA B CB 1 ATOM 5687 N N . ASP B 1 311 ? 123.799 -25.136 64.189 1.00 16.17 ? 313 ASP B N 1 ATOM 5688 C CA . ASP B 1 311 ? 123.008 -26.116 64.932 1.00 16.47 ? 313 ASP B CA 1 ATOM 5689 C C . ASP B 1 311 ? 123.406 -27.549 64.579 1.00 15.94 ? 313 ASP B C 1 ATOM 5690 O O . ASP B 1 311 ? 123.178 -28.473 65.355 1.00 16.21 ? 313 ASP B O 1 ATOM 5691 C CB . ASP B 1 311 ? 121.510 -25.919 64.676 1.00 17.88 ? 313 ASP B CB 1 ATOM 5692 C CG . ASP B 1 311 ? 120.913 -24.798 65.506 1.00 19.05 ? 313 ASP B CG 1 ATOM 5693 O OD1 . ASP B 1 311 ? 121.632 -24.233 66.357 1.00 18.00 ? 313 ASP B OD1 1 ATOM 5694 O OD2 . ASP B 1 311 ? 119.729 -24.462 65.283 1.00 20.08 ? 313 ASP B OD2 1 ATOM 5695 N N . LEU B 1 312 ? 124.001 -27.728 63.405 1.00 14.90 ? 314 LEU B N 1 ATOM 5696 C CA . LEU B 1 312 ? 124.437 -29.049 62.971 1.00 14.19 ? 314 LEU B CA 1 ATOM 5697 C C . LEU B 1 312 ? 125.959 -29.145 62.890 1.00 15.23 ? 314 LEU B C 1 ATOM 5698 O O . LEU B 1 312 ? 126.497 -29.969 62.147 1.00 14.08 ? 314 LEU B O 1 ATOM 5699 C CB . LEU B 1 312 ? 123.818 -29.396 61.614 1.00 14.05 ? 314 LEU B CB 1 ATOM 5700 C CG . LEU B 1 312 ? 122.340 -29.782 61.634 1.00 13.36 ? 314 LEU B CG 1 ATOM 5701 C CD1 . LEU B 1 312 ? 121.870 -30.182 60.245 1.00 13.27 ? 314 LEU B CD1 1 ATOM 5702 C CD2 . LEU B 1 312 ? 122.104 -30.905 62.627 1.00 13.81 ? 314 LEU B CD2 1 ATOM 5703 N N . GLY B 1 313 ? 126.646 -28.290 63.642 1.00 14.28 ? 315 GLY B N 1 ATOM 5704 C CA . GLY B 1 313 ? 128.101 -28.335 63.727 1.00 16.07 ? 315 GLY B CA 1 ATOM 5705 C C . GLY B 1 313 ? 128.786 -27.427 62.724 1.00 17.01 ? 315 GLY B C 1 ATOM 5706 O O . GLY B 1 313 ? 128.148 -26.573 62.109 1.00 15.64 ? 315 GLY B O 1 ATOM 5707 N N . GLY B 1 314 ? 130.095 -27.608 62.569 1.00 17.98 ? 316 GLY B N 1 ATOM 5708 C CA . GLY B 1 314 ? 130.876 -26.797 61.644 1.00 17.45 ? 316 GLY B CA 1 ATOM 5709 C C . GLY B 1 314 ? 131.292 -25.466 62.241 1.00 18.86 ? 316 GLY B C 1 ATOM 5710 O O . GLY B 1 314 ? 131.258 -25.284 63.456 1.00 19.42 ? 316 GLY B O 1 ATOM 5711 N N . SER B 1 315 ? 131.681 -24.529 61.381 1.00 18.28 ? 317 SER B N 1 ATOM 5712 C CA . SER B 1 315 ? 132.280 -23.278 61.834 1.00 20.17 ? 317 SER B CA 1 ATOM 5713 C C . SER B 1 315 ? 131.290 -22.398 62.595 1.00 21.27 ? 317 SER B C 1 ATOM 5714 O O . SER B 1 315 ? 130.172 -22.156 62.133 1.00 19.87 ? 317 SER B O 1 ATOM 5715 C CB . SER B 1 315 ? 132.869 -22.506 60.656 1.00 20.11 ? 317 SER B CB 1 ATOM 5716 O OG . SER B 1 315 ? 133.432 -21.278 61.088 1.00 22.01 ? 317 SER B OG 1 ATOM 5717 N N . LEU B 1 316 ? 131.714 -21.917 63.760 1.00 20.07 ? 318 LEU B N 1 ATOM 5718 C CA . LEU B 1 316 ? 130.921 -20.978 64.547 1.00 19.92 ? 318 LEU B CA 1 ATOM 5719 C C . LEU B 1 316 ? 130.986 -19.577 63.949 1.00 19.93 ? 318 LEU B C 1 ATOM 5720 O O . LEU B 1 316 ? 130.116 -18.744 64.201 1.00 20.08 ? 318 LEU B O 1 ATOM 5721 C CB . LEU B 1 316 ? 131.422 -20.939 65.992 1.00 20.10 ? 318 LEU B CB 1 ATOM 5722 C CG . LEU B 1 316 ? 131.287 -22.230 66.799 1.00 19.78 ? 318 LEU B CG 1 ATOM 5723 C CD1 . LEU B 1 316 ? 131.605 -21.972 68.263 1.00 18.53 ? 318 LEU B CD1 1 ATOM 5724 C CD2 . LEU B 1 316 ? 129.890 -22.812 66.641 1.00 20.04 ? 318 LEU B CD2 1 ATOM 5725 N N . THR B 1 317 ? 132.052 -19.313 63.200 1.00 18.64 ? 319 THR B N 1 ATOM 5726 C CA . THR B 1 317 ? 132.191 -18.068 62.455 1.00 19.37 ? 319 THR B CA 1 ATOM 5727 C C . THR B 1 317 ? 131.859 -18.299 60.981 1.00 18.88 ? 319 THR B C 1 ATOM 5728 O O . THR B 1 317 ? 132.070 -19.391 60.458 1.00 18.36 ? 319 THR B O 1 ATOM 5729 C CB . THR B 1 317 ? 133.628 -17.523 62.545 1.00 19.65 ? 319 THR B CB 1 ATOM 5730 O OG1 . THR B 1 317 ? 134.544 -18.526 62.095 1.00 19.60 ? 319 THR B OG1 1 ATOM 5731 C CG2 . THR B 1 317 ? 133.970 -17.133 63.977 1.00 20.87 ? 319 THR B CG2 1 ATOM 5732 N N . PRO B 1 318 ? 131.331 -17.268 60.309 1.00 19.14 ? 320 PRO B N 1 ATOM 5733 C CA . PRO B 1 318 ? 130.956 -17.381 58.900 1.00 18.78 ? 320 PRO B CA 1 ATOM 5734 C C . PRO B 1 318 ? 132.155 -17.724 58.016 1.00 18.59 ? 320 PRO B C 1 ATOM 5735 O O . PRO B 1 318 ? 133.248 -17.203 58.235 1.00 18.88 ? 320 PRO B O 1 ATOM 5736 C CB . PRO B 1 318 ? 130.443 -15.979 58.567 1.00 19.18 ? 320 PRO B CB 1 ATOM 5737 C CG . PRO B 1 318 ? 129.936 -15.451 59.865 1.00 19.82 ? 320 PRO B CG 1 ATOM 5738 C CD . PRO B 1 318 ? 130.836 -16.022 60.922 1.00 19.23 ? 320 PRO B CD 1 ATOM 5739 N N . PRO B 1 319 ? 131.953 -18.592 57.028 1.00 17.92 ? 321 PRO B N 1 ATOM 5740 C CA . PRO B 1 319 ? 130.657 -19.217 56.790 1.00 17.06 ? 321 PRO B CA 1 ATOM 5741 C C . PRO B 1 319 ? 130.568 -20.578 57.461 1.00 16.93 ? 321 PRO B C 1 ATOM 5742 O O . PRO B 1 319 ? 131.546 -21.326 57.478 1.00 17.52 ? 321 PRO B O 1 ATOM 5743 C CB . PRO B 1 319 ? 130.635 -19.396 55.272 1.00 16.82 ? 321 PRO B CB 1 ATOM 5744 C CG . PRO B 1 319 ? 132.069 -19.564 54.905 1.00 18.14 ? 321 PRO B CG 1 ATOM 5745 C CD . PRO B 1 319 ? 132.828 -18.663 55.844 1.00 18.17 ? 321 PRO B CD 1 ATOM 5746 N N . ASN B 1 320 ? 129.399 -20.901 58.001 1.00 15.89 ? 322 ASN B N 1 ATOM 5747 C CA . ASN B 1 320 ? 129.115 -22.268 58.408 1.00 16.30 ? 322 ASN B CA 1 ATOM 5748 C C . ASN B 1 320 ? 128.800 -23.130 57.190 1.00 16.19 ? 322 ASN B C 1 ATOM 5749 O O . ASN B 1 320 ? 128.092 -22.696 56.280 1.00 15.80 ? 322 ASN B O 1 ATOM 5750 C CB . ASN B 1 320 ? 127.956 -22.300 59.403 1.00 16.02 ? 322 ASN B CB 1 ATOM 5751 C CG . ASN B 1 320 ? 127.620 -23.703 59.860 1.00 16.62 ? 322 ASN B CG 1 ATOM 5752 O OD1 . ASN B 1 320 ? 126.843 -24.408 59.216 1.00 16.66 ? 322 ASN B OD1 1 ATOM 5753 N ND2 . ASN B 1 320 ? 128.189 -24.111 60.991 1.00 16.97 ? 322 ASN B ND2 1 ATOM 5754 N N . LEU B 1 321 ? 129.349 -24.340 57.163 1.00 15.73 ? 323 LEU B N 1 ATOM 5755 C CA . LEU B 1 321 ? 129.269 -25.178 55.973 1.00 16.08 ? 323 LEU B CA 1 ATOM 5756 C C . LEU B 1 321 ? 128.526 -26.485 56.232 1.00 15.23 ? 323 LEU B C 1 ATOM 5757 O O . LEU B 1 321 ? 128.617 -27.424 55.440 1.00 15.46 ? 323 LEU B O 1 ATOM 5758 C CB . LEU B 1 321 ? 130.671 -25.465 55.424 1.00 16.02 ? 323 LEU B CB 1 ATOM 5759 C CG . LEU B 1 321 ? 131.490 -24.243 54.998 1.00 16.56 ? 323 LEU B CG 1 ATOM 5760 C CD1 . LEU B 1 321 ? 132.907 -24.646 54.610 1.00 17.36 ? 323 LEU B CD1 1 ATOM 5761 C CD2 . LEU B 1 321 ? 130.810 -23.498 53.858 1.00 16.46 ? 323 LEU B CD2 1 ATOM 5762 N N . SER B 1 322 ? 127.764 -26.531 57.321 1.00 14.17 ? 324 SER B N 1 ATOM 5763 C CA . SER B 1 322 ? 127.099 -27.766 57.737 1.00 13.75 ? 324 SER B CA 1 ATOM 5764 C C . SER B 1 322 ? 126.017 -28.204 56.757 1.00 13.36 ? 324 SER B C 1 ATOM 5765 O O . SER B 1 322 ? 125.425 -27.376 56.059 1.00 14.47 ? 324 SER B O 1 ATOM 5766 C CB . SER B 1 322 ? 126.494 -27.614 59.134 1.00 13.44 ? 324 SER B CB 1 ATOM 5767 O OG . SER B 1 322 ? 125.235 -26.959 59.079 1.00 13.12 ? 324 SER B OG 1 ATOM 5768 N N . ALA B 1 323 ? 125.748 -29.507 56.739 1.00 12.52 ? 325 ALA B N 1 ATOM 5769 C CA . ALA B 1 323 ? 124.584 -30.067 56.054 1.00 12.94 ? 325 ALA B CA 1 ATOM 5770 C C . ALA B 1 323 ? 124.475 -29.577 54.616 1.00 13.15 ? 325 ALA B C 1 ATOM 5771 O O . ALA B 1 323 ? 123.378 -29.288 54.132 1.00 13.96 ? 325 ALA B O 1 ATOM 5772 C CB . ALA B 1 323 ? 123.308 -29.748 56.820 1.00 12.44 ? 325 ALA B CB 1 ATOM 5773 N N . GLY B 1 324 ? 125.613 -29.477 53.938 1.00 12.32 ? 326 GLY B N 1 ATOM 5774 C CA . GLY B 1 324 ? 125.628 -29.054 52.542 1.00 11.98 ? 326 GLY B CA 1 ATOM 5775 C C . GLY B 1 324 ? 124.772 -29.949 51.665 1.00 13.06 ? 326 GLY B C 1 ATOM 5776 O O . GLY B 1 324 ? 124.098 -29.477 50.744 1.00 13.12 ? 326 GLY B O 1 ATOM 5777 N N . ALA B 1 325 ? 124.789 -31.246 51.954 1.00 13.20 ? 327 ALA B N 1 ATOM 5778 C CA . ALA B 1 325 ? 124.065 -32.218 51.140 1.00 13.84 ? 327 ALA B CA 1 ATOM 5779 C C . ALA B 1 325 ? 122.556 -32.002 51.216 1.00 12.85 ? 327 ALA B C 1 ATOM 5780 O O . ALA B 1 325 ? 121.808 -32.514 50.385 1.00 12.69 ? 327 ALA B O 1 ATOM 5781 C CB . ALA B 1 325 ? 124.419 -33.634 51.562 1.00 15.68 ? 327 ALA B CB 1 ATOM 5782 N N . ASN B 1 326 ? 122.112 -31.273 52.234 1.00 12.20 ? 328 ASN B N 1 ATOM 5783 C CA . ASN B 1 326 ? 120.688 -31.010 52.422 1.00 12.69 ? 328 ASN B CA 1 ATOM 5784 C C . ASN B 1 326 ? 120.253 -29.656 51.860 1.00 12.15 ? 328 ASN B C 1 ATOM 5785 O O . ASN B 1 326 ? 119.226 -29.104 52.261 1.00 12.56 ? 328 ASN B O 1 ATOM 5786 C CB . ASN B 1 326 ? 120.315 -31.122 53.901 1.00 12.84 ? 328 ASN B CB 1 ATOM 5787 C CG . ASN B 1 326 ? 120.611 -32.498 54.472 1.00 14.65 ? 328 ASN B CG 1 ATOM 5788 O OD1 . ASN B 1 326 ? 121.410 -32.640 55.401 1.00 16.16 ? 328 ASN B OD1 1 ATOM 5789 N ND2 . ASN B 1 326 ? 119.985 -33.523 53.901 1.00 14.05 ? 328 ASN B ND2 1 ATOM 5790 N N . SER B 1 327 ? 121.036 -29.124 50.929 1.00 11.95 ? 329 SER B N 1 ATOM 5791 C CA . SER B 1 327 ? 120.738 -27.825 50.340 1.00 11.56 ? 329 SER B CA 1 ATOM 5792 C C . SER B 1 327 ? 119.693 -27.951 49.242 1.00 11.19 ? 329 SER B C 1 ATOM 5793 O O . SER B 1 327 ? 119.615 -28.977 48.566 1.00 11.02 ? 329 SER B O 1 ATOM 5794 C CB . SER B 1 327 ? 122.009 -27.182 49.780 1.00 11.50 ? 329 SER B CB 1 ATOM 5795 O OG . SER B 1 327 ? 122.961 -26.959 50.806 1.00 12.21 ? 329 SER B OG 1 ATOM 5796 N N . ILE B 1 328 ? 118.887 -26.907 49.071 1.00 11.17 ? 330 ILE B N 1 ATOM 5797 C CA . ILE B 1 328 ? 118.004 -26.809 47.910 1.00 11.11 ? 330 ILE B CA 1 ATOM 5798 C C . ILE B 1 328 ? 118.134 -25.450 47.221 1.00 10.97 ? 330 ILE B C 1 ATOM 5799 O O . ILE B 1 328 ? 118.403 -24.442 47.870 1.00 10.01 ? 330 ILE B O 1 ATOM 5800 C CB . ILE B 1 328 ? 116.532 -27.065 48.289 1.00 10.77 ? 330 ILE B CB 1 ATOM 5801 C CG1 . ILE B 1 328 ? 116.037 -26.013 49.284 1.00 10.49 ? 330 ILE B CG1 1 ATOM 5802 C CG2 . ILE B 1 328 ? 116.365 -28.461 48.875 1.00 10.93 ? 330 ILE B CG2 1 ATOM 5803 C CD1 . ILE B 1 328 ? 114.537 -26.039 49.500 1.00 10.05 ? 330 ILE B CD1 1 ATOM 5804 N N . MET B 1 329 ? 117.999 -25.442 45.897 1.00 11.72 ? 331 MET B N 1 ATOM 5805 C CA . MET B 1 329 ? 117.838 -24.199 45.149 1.00 12.41 ? 331 MET B CA 1 ATOM 5806 C C . MET B 1 329 ? 116.360 -23.836 45.033 1.00 12.11 ? 331 MET B C 1 ATOM 5807 O O . MET B 1 329 ? 115.555 -24.630 44.550 1.00 12.63 ? 331 MET B O 1 ATOM 5808 C CB . MET B 1 329 ? 118.444 -24.333 43.751 1.00 13.03 ? 331 MET B CB 1 ATOM 5809 C CG . MET B 1 329 ? 119.960 -24.324 43.732 1.00 15.31 ? 331 MET B CG 1 ATOM 5810 S SD . MET B 1 329 ? 120.628 -22.709 44.179 1.00 18.36 ? 331 MET B SD 1 ATOM 5811 C CE . MET B 1 329 ? 122.245 -22.824 43.415 1.00 21.60 ? 331 MET B CE 1 ATOM 5812 N N . ARG B 1 330 ? 116.008 -22.634 45.474 1.00 11.99 ? 332 ARG B N 1 ATOM 5813 C CA . ARG B 1 330 ? 114.613 -22.203 45.480 1.00 11.82 ? 332 ARG B CA 1 ATOM 5814 C C . ARG B 1 330 ? 114.327 -21.215 44.353 1.00 12.05 ? 332 ARG B C 1 ATOM 5815 O O . ARG B 1 330 ? 115.021 -20.205 44.212 1.00 12.89 ? 332 ARG B O 1 ATOM 5816 C CB . ARG B 1 330 ? 114.249 -21.584 46.834 1.00 12.34 ? 332 ARG B CB 1 ATOM 5817 C CG . ARG B 1 330 ? 114.077 -22.602 47.952 1.00 12.87 ? 332 ARG B CG 1 ATOM 5818 C CD . ARG B 1 330 ? 113.909 -21.928 49.307 1.00 13.55 ? 332 ARG B CD 1 ATOM 5819 N NE . ARG B 1 330 ? 114.949 -20.929 49.544 1.00 13.13 ? 332 ARG B NE 1 ATOM 5820 C CZ . ARG B 1 330 ? 114.716 -19.642 49.774 1.00 13.91 ? 332 ARG B CZ 1 ATOM 5821 N NH1 . ARG B 1 330 ? 113.468 -19.190 49.855 1.00 13.36 ? 332 ARG B NH1 1 ATOM 5822 N NH2 . ARG B 1 330 ? 115.734 -18.807 49.951 1.00 14.45 ? 332 ARG B NH2 1 ATOM 5823 N N . SER B 1 331 ? 113.318 -21.523 43.543 1.00 11.28 ? 333 SER B N 1 ATOM 5824 C CA . SER B 1 331 ? 112.889 -20.636 42.467 1.00 11.79 ? 333 SER B CA 1 ATOM 5825 C C . SER B 1 331 ? 111.383 -20.382 42.513 1.00 11.28 ? 333 SER B C 1 ATOM 5826 O O . SER B 1 331 ? 110.730 -20.279 41.475 1.00 11.25 ? 333 SER B O 1 ATOM 5827 C CB . SER B 1 331 ? 113.270 -21.218 41.104 1.00 12.08 ? 333 SER B CB 1 ATOM 5828 O OG . SER B 1 331 ? 114.666 -21.446 41.025 1.00 14.47 ? 333 SER B OG 1 ATOM 5829 N N . GLY B 1 332 ? 110.835 -20.307 43.721 1.00 11.87 ? 334 GLY B N 1 ATOM 5830 C CA . GLY B 1 332 ? 109.409 -20.047 43.901 1.00 12.21 ? 334 GLY B CA 1 ATOM 5831 C C . GLY B 1 332 ? 109.004 -18.633 43.526 1.00 11.29 ? 334 GLY B C 1 ATOM 5832 O O . GLY B 1 332 ? 109.839 -17.727 43.466 1.00 11.60 ? 334 GLY B O 1 ATOM 5833 N N . ILE B 1 333 ? 107.710 -18.443 43.288 1.00 10.43 ? 335 ILE B N 1 ATOM 5834 C CA . ILE B 1 333 ? 107.176 -17.142 42.901 1.00 10.01 ? 335 ILE B CA 1 ATOM 5835 C C . ILE B 1 333 ? 105.714 -17.049 43.343 1.00 9.99 ? 335 ILE B C 1 ATOM 5836 O O . ILE B 1 333 ? 104.982 -18.037 43.281 1.00 9.55 ? 335 ILE B O 1 ATOM 5837 C CB . ILE B 1 333 ? 107.302 -16.933 41.373 1.00 10.48 ? 335 ILE B CB 1 ATOM 5838 C CG1 . ILE B 1 333 ? 106.600 -15.648 40.932 1.00 10.27 ? 335 ILE B CG1 1 ATOM 5839 C CG2 . ILE B 1 333 ? 106.763 -18.141 40.620 1.00 10.01 ? 335 ILE B CG2 1 ATOM 5840 C CD1 . ILE B 1 333 ? 107.017 -15.178 39.553 1.00 10.91 ? 335 ILE B CD1 1 ATOM 5841 N N . PRO B 1 334 ? 105.299 -15.879 43.861 1.00 10.05 ? 336 PRO B N 1 ATOM 5842 C CA . PRO B 1 334 ? 103.949 -15.776 44.419 1.00 9.82 ? 336 PRO B CA 1 ATOM 5843 C C . PRO B 1 334 ? 102.885 -15.916 43.338 1.00 10.54 ? 336 PRO B C 1 ATOM 5844 O O . PRO B 1 334 ? 103.182 -15.724 42.156 1.00 10.67 ? 336 PRO B O 1 ATOM 5845 C CB . PRO B 1 334 ? 103.921 -14.363 45.018 1.00 9.89 ? 336 PRO B CB 1 ATOM 5846 C CG . PRO B 1 334 ? 105.356 -14.026 45.262 1.00 9.94 ? 336 PRO B CG 1 ATOM 5847 C CD . PRO B 1 334 ? 106.103 -14.676 44.133 1.00 9.95 ? 336 PRO B CD 1 ATOM 5848 N N . TYR B 1 335 ? 101.682 -16.329 43.737 1.00 10.76 ? 337 TYR B N 1 ATOM 5849 C CA . TYR B 1 335 ? 100.532 -16.357 42.837 1.00 11.53 ? 337 TYR B CA 1 ATOM 5850 C C . TYR B 1 335 ? 99.289 -15.765 43.492 1.00 11.61 ? 337 TYR B C 1 ATOM 5851 O O . TYR B 1 335 ? 99.172 -15.729 44.720 1.00 11.11 ? 337 TYR B O 1 ATOM 5852 C CB . TYR B 1 335 ? 100.238 -17.786 42.351 1.00 11.52 ? 337 TYR B CB 1 ATOM 5853 C CG . TYR B 1 335 ? 99.595 -18.692 43.384 1.00 11.68 ? 337 TYR B CG 1 ATOM 5854 C CD1 . TYR B 1 335 ? 98.210 -18.765 43.517 1.00 12.66 ? 337 TYR B CD1 1 ATOM 5855 C CD2 . TYR B 1 335 ? 100.373 -19.501 44.203 1.00 12.43 ? 337 TYR B CD2 1 ATOM 5856 C CE1 . TYR B 1 335 ? 97.623 -19.596 44.459 1.00 13.32 ? 337 TYR B CE1 1 ATOM 5857 C CE2 . TYR B 1 335 ? 99.796 -20.341 45.138 1.00 12.74 ? 337 TYR B CE2 1 ATOM 5858 C CZ . TYR B 1 335 ? 98.423 -20.390 45.260 1.00 13.48 ? 337 TYR B CZ 1 ATOM 5859 O OH . TYR B 1 335 ? 97.859 -21.232 46.196 1.00 13.48 ? 337 TYR B OH 1 ATOM 5860 N N . GLY B 1 336 ? 98.361 -15.304 42.663 1.00 12.39 ? 338 GLY B N 1 ATOM 5861 C CA . GLY B 1 336 ? 97.083 -14.808 43.153 1.00 11.89 ? 338 GLY B CA 1 ATOM 5862 C C . GLY B 1 336 ? 97.075 -13.303 43.297 1.00 12.40 ? 338 GLY B C 1 ATOM 5863 O O . GLY B 1 336 ? 98.107 -12.648 43.129 1.00 13.03 ? 338 GLY B O 1 ATOM 5864 N N . PRO B 1 337 ? 95.901 -12.740 43.609 1.00 11.96 ? 339 PRO B N 1 ATOM 5865 C CA . PRO B 1 337 ? 95.753 -11.299 43.777 1.00 12.02 ? 339 PRO B CA 1 ATOM 5866 C C . PRO B 1 337 ? 96.382 -10.809 45.077 1.00 12.47 ? 339 PRO B C 1 ATOM 5867 O O . PRO B 1 337 ? 96.550 -11.587 46.020 1.00 11.40 ? 339 PRO B O 1 ATOM 5868 C CB . PRO B 1 337 ? 94.236 -11.108 43.822 1.00 11.68 ? 339 PRO B CB 1 ATOM 5869 C CG . PRO B 1 337 ? 93.711 -12.403 44.345 1.00 11.83 ? 339 PRO B CG 1 ATOM 5870 C CD . PRO B 1 337 ? 94.631 -13.462 43.805 1.00 11.91 ? 339 PRO B CD 1 ATOM 5871 N N . GLU B 1 338 ? 96.726 -9.525 45.121 1.00 12.28 ? 340 GLU B N 1 ATOM 5872 C CA . GLU B 1 338 ? 97.069 -8.875 46.378 1.00 12.55 ? 340 GLU B CA 1 ATOM 5873 C C . GLU B 1 338 ? 95.887 -8.955 47.331 1.00 12.54 ? 340 GLU B C 1 ATOM 5874 O O . GLU B 1 338 ? 94.737 -9.060 46.899 1.00 12.15 ? 340 GLU B O 1 ATOM 5875 C CB . GLU B 1 338 ? 97.452 -7.413 46.141 1.00 13.25 ? 340 GLU B CB 1 ATOM 5876 C CG . GLU B 1 338 ? 98.754 -7.230 45.380 1.00 13.57 ? 340 GLU B CG 1 ATOM 5877 C CD . GLU B 1 338 ? 99.957 -7.666 46.192 1.00 13.89 ? 340 GLU B CD 1 ATOM 5878 O OE1 . GLU B 1 338 ? 100.195 -7.069 47.264 1.00 15.29 ? 340 GLU B OE1 1 ATOM 5879 O OE2 . GLU B 1 338 ? 100.637 -8.629 45.782 1.00 14.33 ? 340 GLU B OE2 1 ATOM 5880 N N . VAL B 1 339 ? 96.169 -8.903 48.629 1.00 12.33 ? 341 VAL B N 1 ATOM 5881 C CA . VAL B 1 339 ? 95.111 -8.871 49.627 1.00 12.50 ? 341 VAL B CA 1 ATOM 5882 C C . VAL B 1 339 ? 94.205 -7.659 49.421 1.00 13.59 ? 341 VAL B C 1 ATOM 5883 O O . VAL B 1 339 ? 94.681 -6.535 49.272 1.00 13.39 ? 341 VAL B O 1 ATOM 5884 C CB . VAL B 1 339 ? 95.691 -8.851 51.053 1.00 12.34 ? 341 VAL B CB 1 ATOM 5885 C CG1 . VAL B 1 339 ? 94.571 -8.878 52.080 1.00 11.84 ? 341 VAL B CG1 1 ATOM 5886 C CG2 . VAL B 1 339 ? 96.637 -10.030 51.253 1.00 12.59 ? 341 VAL B CG2 1 ATOM 5887 N N . THR B 1 340 ? 92.900 -7.903 49.372 1.00 13.73 ? 342 THR B N 1 ATOM 5888 C CA . THR B 1 340 ? 91.927 -6.841 49.141 1.00 15.35 ? 342 THR B CA 1 ATOM 5889 C C . THR B 1 340 ? 91.584 -6.158 50.458 1.00 16.13 ? 342 THR B C 1 ATOM 5890 O O . THR B 1 340 ? 91.821 -6.711 51.528 1.00 16.13 ? 342 THR B O 1 ATOM 5891 C CB . THR B 1 340 ? 90.633 -7.405 48.533 1.00 15.89 ? 342 THR B CB 1 ATOM 5892 O OG1 . THR B 1 340 ? 90.055 -8.347 49.442 1.00 15.88 ? 342 THR B OG1 1 ATOM 5893 C CG2 . THR B 1 340 ? 90.920 -8.100 47.203 1.00 15.03 ? 342 THR B CG2 1 ATOM 5894 N N . SER B 1 341 ? 90.992 -4.971 50.382 1.00 18.39 ? 343 SER B N 1 ATOM 5895 C CA . SER B 1 341 ? 90.621 -4.246 51.592 1.00 19.40 ? 343 SER B CA 1 ATOM 5896 C C . SER B 1 341 ? 89.551 -4.983 52.397 1.00 18.64 ? 343 SER B C 1 ATOM 5897 O O . SER B 1 341 ? 89.581 -4.982 53.628 1.00 19.31 ? 343 SER B O 1 ATOM 5898 C CB . SER B 1 341 ? 90.163 -2.825 51.258 1.00 20.80 ? 343 SER B CB 1 ATOM 5899 O OG . SER B 1 341 ? 89.105 -2.845 50.321 1.00 25.50 ? 343 SER B OG 1 ATOM 5900 N N . ALA B 1 342 ? 88.637 -5.653 51.700 1.00 18.54 ? 344 ALA B N 1 ATOM 5901 C CA . ALA B 1 342 ? 87.574 -6.407 52.363 1.00 17.80 ? 344 ALA B CA 1 ATOM 5902 C C . ALA B 1 342 ? 88.122 -7.586 53.165 1.00 18.91 ? 344 ALA B C 1 ATOM 5903 O O . ALA B 1 342 ? 87.687 -7.842 54.291 1.00 17.63 ? 344 ALA B O 1 ATOM 5904 C CB . ALA B 1 342 ? 86.545 -6.884 51.351 1.00 17.68 ? 344 ALA B CB 1 ATOM 5905 N N . GLU B 1 343 ? 89.051 -8.323 52.567 1.00 17.50 ? 345 GLU B N 1 ATOM 5906 C CA . GLU B 1 343 ? 89.700 -9.434 53.253 1.00 17.14 ? 345 GLU B CA 1 ATOM 5907 C C . GLU B 1 343 ? 90.461 -8.939 54.473 1.00 18.29 ? 345 GLU B C 1 ATOM 5908 O O . GLU B 1 343 ? 90.422 -9.555 55.536 1.00 18.50 ? 345 GLU B O 1 ATOM 5909 C CB . GLU B 1 343 ? 90.651 -10.162 52.305 1.00 15.30 ? 345 GLU B CB 1 ATOM 5910 C CG . GLU B 1 343 ? 89.954 -11.113 51.348 1.00 15.30 ? 345 GLU B CG 1 ATOM 5911 C CD . GLU B 1 343 ? 90.887 -11.627 50.273 1.00 14.26 ? 345 GLU B CD 1 ATOM 5912 O OE1 . GLU B 1 343 ? 91.419 -10.797 49.505 1.00 13.79 ? 345 GLU B OE1 1 ATOM 5913 O OE2 . GLU B 1 343 ? 91.101 -12.856 50.211 1.00 13.94 ? 345 GLU B OE2 1 ATOM 5914 N N . SER B 1 344 ? 91.144 -7.812 54.315 1.00 21.10 ? 346 SER B N 1 ATOM 5915 C CA . SER B 1 344 ? 91.918 -7.234 55.405 1.00 23.90 ? 346 SER B CA 1 ATOM 5916 C C . SER B 1 344 ? 91.024 -6.803 56.559 1.00 22.84 ? 346 SER B C 1 ATOM 5917 O O . SER B 1 344 ? 91.343 -7.039 57.724 1.00 22.34 ? 346 SER B O 1 ATOM 5918 C CB . SER B 1 344 ? 92.738 -6.046 54.909 1.00 25.17 ? 346 SER B CB 1 ATOM 5919 O OG . SER B 1 344 ? 93.740 -5.710 55.851 1.00 32.78 ? 346 SER B OG 1 ATOM 5920 N N . ALA B 1 345 ? 89.911 -6.157 56.232 1.00 23.30 ? 347 ALA B N 1 ATOM 5921 C CA . ALA B 1 345 ? 88.987 -5.676 57.250 1.00 24.22 ? 347 ALA B CA 1 ATOM 5922 C C . ALA B 1 345 ? 88.365 -6.829 58.031 1.00 24.03 ? 347 ALA B C 1 ATOM 5923 O O . ALA B 1 345 ? 88.091 -6.704 59.224 1.00 25.77 ? 347 ALA B O 1 ATOM 5924 C CB . ALA B 1 345 ? 87.905 -4.811 56.620 1.00 24.76 ? 347 ALA B CB 1 ATOM 5925 N N . SER B 1 346 ? 88.159 -7.958 57.361 1.00 22.59 ? 348 SER B N 1 ATOM 5926 C CA . SER B 1 346 ? 87.449 -9.079 57.966 1.00 20.49 ? 348 SER B CA 1 ATOM 5927 C C . SER B 1 346 ? 88.398 -10.111 58.568 1.00 19.22 ? 348 SER B C 1 ATOM 5928 O O . SER B 1 346 ? 87.965 -11.022 59.268 1.00 18.30 ? 348 SER B O 1 ATOM 5929 C CB . SER B 1 346 ? 86.530 -9.747 56.942 1.00 20.67 ? 348 SER B CB 1 ATOM 5930 O OG . SER B 1 346 ? 87.283 -10.385 55.925 1.00 21.12 ? 348 SER B OG 1 ATOM 5931 N N . ASN B 1 347 ? 89.688 -9.970 58.284 1.00 19.17 ? 349 ASN B N 1 ATOM 5932 C CA . ASN B 1 347 ? 90.684 -10.957 58.699 1.00 19.47 ? 349 ASN B CA 1 ATOM 5933 C C . ASN B 1 347 ? 90.454 -12.331 58.085 1.00 18.22 ? 349 ASN B C 1 ATOM 5934 O O . ASN B 1 347 ? 90.917 -13.341 58.615 1.00 16.47 ? 349 ASN B O 1 ATOM 5935 C CB . ASN B 1 347 ? 90.723 -11.082 60.222 1.00 19.67 ? 349 ASN B CB 1 ATOM 5936 C CG . ASN B 1 347 ? 90.910 -9.750 60.911 1.00 20.76 ? 349 ASN B CG 1 ATOM 5937 O OD1 . ASN B 1 347 ? 91.805 -8.977 60.565 1.00 18.89 ? 349 ASN B OD1 1 ATOM 5938 N ND2 . ASN B 1 347 ? 90.062 -9.471 61.891 1.00 23.45 ? 349 ASN B ND2 1 ATOM 5939 N N . THR B 1 348 ? 89.753 -12.364 56.958 1.00 18.38 ? 350 THR B N 1 ATOM 5940 C CA . THR B 1 348 ? 89.372 -13.625 56.342 1.00 18.94 ? 350 THR B CA 1 ATOM 5941 C C . THR B 1 348 ? 89.718 -13.642 54.857 1.00 17.30 ? 350 THR B C 1 ATOM 5942 O O . THR B 1 348 ? 89.284 -12.775 54.100 1.00 16.35 ? 350 THR B O 1 ATOM 5943 C CB . THR B 1 348 ? 87.867 -13.897 56.514 1.00 20.22 ? 350 THR B CB 1 ATOM 5944 O OG1 . THR B 1 348 ? 87.539 -13.893 57.909 1.00 23.70 ? 350 THR B OG1 1 ATOM 5945 C CG2 . THR B 1 348 ? 87.494 -15.244 55.912 1.00 19.54 ? 350 THR B CG2 1 ATOM 5946 N N . THR B 1 349 ? 90.491 -14.643 54.449 1.00 15.96 ? 351 THR B N 1 ATOM 5947 C CA . THR B 1 349 ? 90.787 -14.865 53.038 1.00 14.82 ? 351 THR B CA 1 ATOM 5948 C C . THR B 1 349 ? 89.532 -15.267 52.265 1.00 15.29 ? 351 THR B C 1 ATOM 5949 O O . THR B 1 349 ? 88.791 -16.145 52.698 1.00 15.72 ? 351 THR B O 1 ATOM 5950 C CB . THR B 1 349 ? 91.841 -15.978 52.869 1.00 14.56 ? 351 THR B CB 1 ATOM 5951 O OG1 . THR B 1 349 ? 93.096 -15.532 53.397 1.00 13.66 ? 351 THR B OG1 1 ATOM 5952 C CG2 . THR B 1 349 ? 92.009 -16.338 51.392 1.00 13.98 ? 351 THR B CG2 1 ATOM 5953 N N . THR B 1 350 ? 89.316 -14.654 51.103 1.00 15.67 ? 352 THR B N 1 ATOM 5954 C CA . THR B 1 350 ? 88.321 -15.155 50.154 1.00 15.79 ? 352 THR B CA 1 ATOM 5955 C C . THR B 1 350 ? 88.903 -15.438 48.770 1.00 15.47 ? 352 THR B C 1 ATOM 5956 O O . THR B 1 350 ? 88.313 -16.182 47.984 1.00 16.21 ? 352 THR B O 1 ATOM 5957 C CB . THR B 1 350 ? 87.117 -14.200 50.006 1.00 16.28 ? 352 THR B CB 1 ATOM 5958 O OG1 . THR B 1 350 ? 87.538 -12.991 49.362 1.00 14.95 ? 352 THR B OG1 1 ATOM 5959 C CG2 . THR B 1 350 ? 86.523 -13.871 51.367 1.00 17.38 ? 352 THR B CG2 1 ATOM 5960 N N . GLN B 1 351 ? 90.029 -14.807 48.455 1.00 14.84 ? 353 GLN B N 1 ATOM 5961 C CA . GLN B 1 351 ? 90.690 -15.021 47.171 1.00 14.71 ? 353 GLN B CA 1 ATOM 5962 C C . GLN B 1 351 ? 91.959 -15.849 47.371 1.00 15.50 ? 353 GLN B C 1 ATOM 5963 O O . GLN B 1 351 ? 92.801 -15.509 48.200 1.00 15.37 ? 353 GLN B O 1 ATOM 5964 C CB . GLN B 1 351 ? 91.033 -13.680 46.514 1.00 15.01 ? 353 GLN B CB 1 ATOM 5965 C CG . GLN B 1 351 ? 89.927 -12.635 46.607 1.00 15.11 ? 353 GLN B CG 1 ATOM 5966 C CD . GLN B 1 351 ? 88.602 -13.138 46.067 1.00 15.07 ? 353 GLN B CD 1 ATOM 5967 O OE1 . GLN B 1 351 ? 87.610 -13.212 46.794 1.00 14.49 ? 353 GLN B OE1 1 ATOM 5968 N NE2 . GLN B 1 351 ? 88.586 -13.515 44.791 1.00 14.69 ? 353 GLN B NE2 1 ATOM 5969 N N . GLU B 1 352 ? 92.069 -16.966 46.658 1.00 14.34 ? 354 GLU B N 1 ATOM 5970 C CA . GLU B 1 352 ? 93.222 -17.840 46.833 1.00 15.14 ? 354 GLU B CA 1 ATOM 5971 C C . GLU B 1 352 ? 94.496 -17.156 46.351 1.00 14.75 ? 354 GLU B C 1 ATOM 5972 O O . GLU B 1 352 ? 94.541 -16.599 45.255 1.00 13.67 ? 354 GLU B O 1 ATOM 5973 C CB . GLU B 1 352 ? 93.030 -19.188 46.130 1.00 16.24 ? 354 GLU B CB 1 ATOM 5974 C CG . GLU B 1 352 ? 93.902 -20.296 46.714 1.00 18.22 ? 354 GLU B CG 1 ATOM 5975 C CD . GLU B 1 352 ? 94.126 -21.454 45.757 1.00 19.74 ? 354 GLU B CD 1 ATOM 5976 O OE1 . GLU B 1 352 ? 93.212 -21.760 44.964 1.00 21.68 ? 354 GLU B OE1 1 ATOM 5977 O OE2 . GLU B 1 352 ? 95.210 -22.079 45.818 1.00 19.78 ? 354 GLU B OE2 1 ATOM 5978 N N . ARG B 1 353 ? 95.495 -17.123 47.221 1.00 13.17 ? 355 ARG B N 1 ATOM 5979 C CA . ARG B 1 353 ? 96.805 -16.595 46.878 1.00 12.85 ? 355 ARG B CA 1 ATOM 5980 C C . ARG B 1 353 ? 97.839 -17.409 47.637 1.00 12.10 ? 355 ARG B C 1 ATOM 5981 O O . ARG B 1 353 ? 97.503 -18.103 48.595 1.00 12.39 ? 355 ARG B O 1 ATOM 5982 C CB . ARG B 1 353 ? 96.904 -15.120 47.286 1.00 12.23 ? 355 ARG B CB 1 ATOM 5983 C CG . ARG B 1 353 ? 96.640 -14.875 48.765 1.00 11.97 ? 355 ARG B CG 1 ATOM 5984 C CD . ARG B 1 353 ? 96.780 -13.405 49.130 1.00 12.32 ? 355 ARG B CD 1 ATOM 5985 N NE . ARG B 1 353 ? 95.784 -12.573 48.456 1.00 12.17 ? 355 ARG B NE 1 ATOM 5986 C CZ . ARG B 1 353 ? 94.521 -12.442 48.854 1.00 11.86 ? 355 ARG B CZ 1 ATOM 5987 N NH1 . ARG B 1 353 ? 94.091 -13.078 49.936 1.00 11.55 ? 355 ARG B NH1 1 ATOM 5988 N NH2 . ARG B 1 353 ? 93.687 -11.666 48.170 1.00 11.41 ? 355 ARG B NH2 1 ATOM 5989 N N . GLY B 1 354 ? 99.102 -17.293 47.245 1.00 12.47 ? 356 GLY B N 1 ATOM 5990 C CA . GLY B 1 354 ? 100.172 -17.969 47.971 1.00 11.70 ? 356 GLY B CA 1 ATOM 5991 C C . GLY B 1 354 ? 101.482 -18.042 47.216 1.00 11.12 ? 356 GLY B C 1 ATOM 5992 O O . GLY B 1 354 ? 101.878 -17.093 46.539 1.00 10.61 ? 356 GLY B O 1 ATOM 5993 N N . LEU B 1 355 ? 102.170 -19.171 47.362 1.00 10.49 ? 357 LEU B N 1 ATOM 5994 C CA . LEU B 1 355 ? 103.489 -19.356 46.774 1.00 10.12 ? 357 LEU B CA 1 ATOM 5995 C C . LEU B 1 355 ? 103.496 -20.559 45.845 1.00 9.88 ? 357 LEU B C 1 ATOM 5996 O O . LEU B 1 355 ? 103.193 -21.673 46.265 1.00 10.14 ? 357 LEU B O 1 ATOM 5997 C CB . LEU B 1 355 ? 104.535 -19.559 47.874 1.00 10.47 ? 357 LEU B CB 1 ATOM 5998 C CG . LEU B 1 355 ? 105.989 -19.663 47.405 1.00 10.61 ? 357 LEU B CG 1 ATOM 5999 C CD1 . LEU B 1 355 ? 106.448 -18.368 46.751 1.00 10.52 ? 357 LEU B CD1 1 ATOM 6000 C CD2 . LEU B 1 355 ? 106.898 -20.042 48.566 1.00 11.05 ? 357 LEU B CD2 1 ATOM 6001 N N . ALA B 1 356 ? 103.836 -20.331 44.581 1.00 9.25 ? 358 ALA B N 1 ATOM 6002 C CA . ALA B 1 356 ? 104.206 -21.418 43.687 1.00 9.16 ? 358 ALA B CA 1 ATOM 6003 C C . ALA B 1 356 ? 105.625 -21.875 44.009 1.00 9.15 ? 358 ALA B C 1 ATOM 6004 O O . ALA B 1 356 ? 106.600 -21.333 43.487 1.00 9.37 ? 358 ALA B O 1 ATOM 6005 C CB . ALA B 1 356 ? 104.101 -20.974 42.234 1.00 9.04 ? 358 ALA B CB 1 ATOM 6006 N N . PHE B 1 357 ? 105.732 -22.821 44.934 1.00 9.34 ? 359 PHE B N 1 ATOM 6007 C CA . PHE B 1 357 ? 107.016 -23.205 45.499 1.00 9.51 ? 359 PHE B CA 1 ATOM 6008 C C . PHE B 1 357 ? 107.760 -24.138 44.552 1.00 9.47 ? 359 PHE B C 1 ATOM 6009 O O . PHE B 1 357 ? 107.206 -25.135 44.089 1.00 9.24 ? 359 PHE B O 1 ATOM 6010 C CB . PHE B 1 357 ? 106.807 -23.887 46.854 1.00 10.02 ? 359 PHE B CB 1 ATOM 6011 C CG . PHE B 1 357 ? 108.071 -24.409 47.475 1.00 10.34 ? 359 PHE B CG 1 ATOM 6012 C CD1 . PHE B 1 357 ? 108.862 -23.589 48.265 1.00 10.63 ? 359 PHE B CD1 1 ATOM 6013 C CD2 . PHE B 1 357 ? 108.456 -25.727 47.289 1.00 10.54 ? 359 PHE B CD2 1 ATOM 6014 C CE1 . PHE B 1 357 ? 110.014 -24.075 48.857 1.00 11.01 ? 359 PHE B CE1 1 ATOM 6015 C CE2 . PHE B 1 357 ? 109.601 -26.223 47.889 1.00 9.99 ? 359 PHE B CE2 1 ATOM 6016 C CZ . PHE B 1 357 ? 110.388 -25.392 48.663 1.00 10.22 ? 359 PHE B CZ 1 ATOM 6017 N N . VAL B 1 358 ? 109.012 -23.799 44.259 1.00 8.61 ? 360 VAL B N 1 ATOM 6018 C CA . VAL B 1 358 ? 109.866 -24.646 43.438 1.00 8.71 ? 360 VAL B CA 1 ATOM 6019 C C . VAL B 1 358 ? 111.197 -24.876 44.144 1.00 8.59 ? 360 VAL B C 1 ATOM 6020 O O . VAL B 1 358 ? 111.876 -23.922 44.535 1.00 9.00 ? 360 VAL B O 1 ATOM 6021 C CB . VAL B 1 358 ? 110.133 -24.008 42.054 1.00 8.80 ? 360 VAL B CB 1 ATOM 6022 C CG1 . VAL B 1 358 ? 111.007 -24.919 41.204 1.00 8.53 ? 360 VAL B CG1 1 ATOM 6023 C CG2 . VAL B 1 358 ? 108.825 -23.698 41.337 1.00 8.84 ? 360 VAL B CG2 1 ATOM 6024 N N . ALA B 1 359 ? 111.554 -26.144 44.330 1.00 8.51 ? 361 ALA B N 1 ATOM 6025 C CA . ALA B 1 359 ? 112.861 -26.508 44.865 1.00 8.41 ? 361 ALA B CA 1 ATOM 6026 C C . ALA B 1 359 ? 113.596 -27.446 43.912 1.00 8.44 ? 361 ALA B C 1 ATOM 6027 O O . ALA B 1 359 ? 113.018 -28.410 43.411 1.00 8.12 ? 361 ALA B O 1 ATOM 6028 C CB . ALA B 1 359 ? 112.715 -27.158 46.234 1.00 8.13 ? 361 ALA B CB 1 ATOM 6029 N N . TYR B 1 360 ? 114.878 -27.168 43.691 1.00 8.21 ? 362 TYR B N 1 ATOM 6030 C CA . TYR B 1 360 ? 115.728 -28.037 42.886 1.00 8.13 ? 362 TYR B CA 1 ATOM 6031 C C . TYR B 1 360 ? 116.770 -28.729 43.757 1.00 7.80 ? 362 TYR B C 1 ATOM 6032 O O . TYR B 1 360 ? 117.321 -28.129 44.683 1.00 7.75 ? 362 TYR B O 1 ATOM 6033 C CB . TYR B 1 360 ? 116.424 -27.236 41.786 1.00 8.33 ? 362 TYR B CB 1 ATOM 6034 C CG . TYR B 1 360 ? 115.491 -26.730 40.714 1.00 8.71 ? 362 TYR B CG 1 ATOM 6035 C CD1 . TYR B 1 360 ? 115.064 -27.565 39.693 1.00 8.81 ? 362 TYR B CD1 1 ATOM 6036 C CD2 . TYR B 1 360 ? 115.019 -25.422 40.734 1.00 9.33 ? 362 TYR B CD2 1 ATOM 6037 C CE1 . TYR B 1 360 ? 114.222 -27.107 38.701 1.00 9.39 ? 362 TYR B CE1 1 ATOM 6038 C CE2 . TYR B 1 360 ? 114.160 -24.958 39.755 1.00 9.30 ? 362 TYR B CE2 1 ATOM 6039 C CZ . TYR B 1 360 ? 113.768 -25.805 38.741 1.00 9.44 ? 362 TYR B CZ 1 ATOM 6040 O OH . TYR B 1 360 ? 112.918 -25.355 37.760 1.00 10.44 ? 362 TYR B OH 1 ATOM 6041 N N . GLN B 1 361 ? 117.021 -30.001 43.462 1.00 7.67 ? 363 GLN B N 1 ATOM 6042 C CA . GLN B 1 361 ? 117.996 -30.798 44.200 1.00 7.83 ? 363 GLN B CA 1 ATOM 6043 C C . GLN B 1 361 ? 118.280 -32.065 43.404 1.00 8.15 ? 363 GLN B C 1 ATOM 6044 O O . GLN B 1 361 ? 117.464 -32.479 42.578 1.00 8.42 ? 363 GLN B O 1 ATOM 6045 C CB . GLN B 1 361 ? 117.454 -31.165 45.587 1.00 7.62 ? 363 GLN B CB 1 ATOM 6046 C CG . GLN B 1 361 ? 116.178 -31.999 45.561 1.00 7.62 ? 363 GLN B CG 1 ATOM 6047 C CD . GLN B 1 361 ? 114.918 -31.158 45.668 1.00 7.89 ? 363 GLN B CD 1 ATOM 6048 O OE1 . GLN B 1 361 ? 114.546 -30.718 46.756 1.00 8.61 ? 363 GLN B OE1 1 ATOM 6049 N NE2 . GLN B 1 361 ? 114.257 -30.923 44.532 1.00 7.13 ? 363 GLN B NE2 1 ATOM 6050 N N . ALA B 1 362 ? 119.442 -32.669 43.637 1.00 8.32 ? 364 ALA B N 1 ATOM 6051 C CA . ALA B 1 362 ? 119.824 -33.872 42.908 1.00 8.53 ? 364 ALA B CA 1 ATOM 6052 C C . ALA B 1 362 ? 119.242 -35.132 43.542 1.00 9.01 ? 364 ALA B C 1 ATOM 6053 O O . ALA B 1 362 ? 119.081 -36.153 42.874 1.00 8.71 ? 364 ALA B O 1 ATOM 6054 C CB . ALA B 1 362 ? 121.337 -33.974 42.797 1.00 8.45 ? 364 ALA B CB 1 ATOM 6055 N N . GLN B 1 363 ? 118.969 -35.061 44.843 1.00 9.80 ? 365 GLN B N 1 ATOM 6056 C CA . GLN B 1 363 ? 118.289 -36.136 45.557 1.00 10.22 ? 365 GLN B CA 1 ATOM 6057 C C . GLN B 1 363 ? 117.116 -35.574 46.354 1.00 10.52 ? 365 GLN B C 1 ATOM 6058 O O . GLN B 1 363 ? 117.303 -34.775 47.275 1.00 10.45 ? 365 GLN B O 1 ATOM 6059 C CB . GLN B 1 363 ? 119.256 -36.851 46.509 1.00 11.24 ? 365 GLN B CB 1 ATOM 6060 C CG . GLN B 1 363 ? 120.495 -37.423 45.839 1.00 11.85 ? 365 GLN B CG 1 ATOM 6061 C CD . GLN B 1 363 ? 121.401 -38.149 46.819 1.00 13.33 ? 365 GLN B CD 1 ATOM 6062 O OE1 . GLN B 1 363 ? 122.552 -37.760 47.025 1.00 15.34 ? 365 GLN B OE1 1 ATOM 6063 N NE2 . GLN B 1 363 ? 120.876 -39.188 47.450 1.00 12.55 ? 365 GLN B NE2 1 ATOM 6064 N N . LEU B 1 364 ? 115.908 -36.005 46.009 1.00 10.36 ? 366 LEU B N 1 ATOM 6065 C CA . LEU B 1 364 ? 114.717 -35.545 46.712 1.00 10.73 ? 366 LEU B CA 1 ATOM 6066 C C . LEU B 1 364 ? 114.738 -35.956 48.183 1.00 11.33 ? 366 LEU B C 1 ATOM 6067 O O . LEU B 1 364 ? 114.222 -35.244 49.042 1.00 11.29 ? 366 LEU B O 1 ATOM 6068 C CB . LEU B 1 364 ? 113.454 -36.061 46.022 1.00 10.66 ? 366 LEU B CB 1 ATOM 6069 C CG . LEU B 1 364 ? 113.050 -35.295 44.761 1.00 10.76 ? 366 LEU B CG 1 ATOM 6070 C CD1 . LEU B 1 364 ? 112.044 -36.093 43.944 1.00 10.79 ? 366 LEU B CD1 1 ATOM 6071 C CD2 . LEU B 1 364 ? 112.486 -33.929 45.133 1.00 10.60 ? 366 LEU B CD2 1 ATOM 6072 N N . SER B 1 365 ? 115.378 -37.085 48.473 1.00 11.69 ? 367 SER B N 1 ATOM 6073 C CA . SER B 1 365 ? 115.413 -37.614 49.834 1.00 11.52 ? 367 SER B CA 1 ATOM 6074 C C . SER B 1 365 ? 116.298 -36.780 50.754 1.00 12.19 ? 367 SER B C 1 ATOM 6075 O O . SER B 1 365 ? 116.193 -36.873 51.979 1.00 13.18 ? 367 SER B O 1 ATOM 6076 C CB . SER B 1 365 ? 115.900 -39.063 49.827 1.00 12.02 ? 367 SER B CB 1 ATOM 6077 O OG . SER B 1 365 ? 117.261 -39.125 49.448 1.00 11.33 ? 367 SER B OG 1 ATOM 6078 N N . GLN B 1 366 ? 117.171 -35.972 50.158 1.00 13.20 ? 368 GLN B N 1 ATOM 6079 C CA . GLN B 1 366 ? 118.095 -35.124 50.907 1.00 14.40 ? 368 GLN B CA 1 ATOM 6080 C C . GLN B 1 366 ? 117.601 -33.684 50.932 1.00 13.90 ? 368 GLN B C 1 ATOM 6081 O O . GLN B 1 366 ? 117.992 -32.895 51.796 1.00 12.78 ? 368 GLN B O 1 ATOM 6082 C CB . GLN B 1 366 ? 119.486 -35.159 50.265 1.00 16.25 ? 368 GLN B CB 1 ATOM 6083 C CG . GLN B 1 366 ? 120.098 -36.546 50.179 1.00 18.34 ? 368 GLN B CG 1 ATOM 6084 C CD . GLN B 1 366 ? 120.154 -37.231 51.527 1.00 22.10 ? 368 GLN B CD 1 ATOM 6085 O OE1 . GLN B 1 366 ? 120.780 -36.732 52.462 1.00 25.66 ? 368 GLN B OE1 1 ATOM 6086 N NE2 . GLN B 1 366 ? 119.480 -38.371 51.642 1.00 23.60 ? 368 GLN B NE2 1 ATOM 6087 N N . GLY B 1 367 ? 116.771 -33.338 49.954 1.00 12.71 ? 369 GLY B N 1 ATOM 6088 C CA . GLY B 1 367 ? 116.365 -31.954 49.749 1.00 11.78 ? 369 GLY B CA 1 ATOM 6089 C C . GLY B 1 367 ? 114.995 -31.669 50.326 1.00 12.17 ? 369 GLY B C 1 ATOM 6090 O O . GLY B 1 367 ? 114.760 -31.859 51.521 1.00 12.11 ? 369 GLY B O 1 ATOM 6091 N N . PHE B 1 368 ? 114.084 -31.226 49.466 1.00 12.17 ? 370 PHE B N 1 ATOM 6092 C CA . PHE B 1 368 ? 112.752 -30.803 49.893 1.00 12.69 ? 370 PHE B CA 1 ATOM 6093 C C . PHE B 1 368 ? 112.099 -31.794 50.855 1.00 13.05 ? 370 PHE B C 1 ATOM 6094 O O . PHE B 1 368 ? 111.571 -31.406 51.901 1.00 13.30 ? 370 PHE B O 1 ATOM 6095 C CB . PHE B 1 368 ? 111.841 -30.587 48.683 1.00 12.31 ? 370 PHE B CB 1 ATOM 6096 C CG . PHE B 1 368 ? 110.379 -30.648 49.018 1.00 12.71 ? 370 PHE B CG 1 ATOM 6097 C CD1 . PHE B 1 368 ? 109.773 -29.614 49.713 1.00 12.95 ? 370 PHE B CD1 1 ATOM 6098 C CD2 . PHE B 1 368 ? 109.633 -31.777 48.721 1.00 13.29 ? 370 PHE B CD2 1 ATOM 6099 C CE1 . PHE B 1 368 ? 108.441 -29.688 50.074 1.00 12.35 ? 370 PHE B CE1 1 ATOM 6100 C CE2 . PHE B 1 368 ? 108.298 -31.857 49.079 1.00 13.01 ? 370 PHE B CE2 1 ATOM 6101 C CZ . PHE B 1 368 ? 107.704 -30.812 49.760 1.00 12.58 ? 370 PHE B CZ 1 ATOM 6102 N N . HIS B 1 369 ? 112.078 -33.063 50.460 1.00 13.29 ? 371 HIS B N 1 ATOM 6103 C CA . HIS B 1 369 ? 111.385 -34.100 51.220 1.00 13.42 ? 371 HIS B CA 1 ATOM 6104 C C . HIS B 1 369 ? 111.962 -34.192 52.630 1.00 13.80 ? 371 HIS B C 1 ATOM 6105 O O . HIS B 1 369 ? 111.222 -34.276 53.611 1.00 13.41 ? 371 HIS B O 1 ATOM 6106 C CB . HIS B 1 369 ? 111.499 -35.444 50.491 1.00 13.71 ? 371 HIS B CB 1 ATOM 6107 C CG . HIS B 1 369 ? 111.179 -36.635 51.341 1.00 14.17 ? 371 HIS B CG 1 ATOM 6108 N ND1 . HIS B 1 369 ? 109.994 -37.328 51.230 1.00 13.95 ? 371 HIS B ND1 1 ATOM 6109 C CD2 . HIS B 1 369 ? 111.927 -37.312 52.246 1.00 15.47 ? 371 HIS B CD2 1 ATOM 6110 C CE1 . HIS B 1 369 ? 110.008 -38.358 52.058 1.00 15.74 ? 371 HIS B CE1 1 ATOM 6111 N NE2 . HIS B 1 369 ? 111.170 -38.370 52.688 1.00 16.26 ? 371 HIS B NE2 1 ATOM 6112 N N . PHE B 1 370 ? 113.285 -34.102 52.722 1.00 13.37 ? 372 PHE B N 1 ATOM 6113 C CA . PHE B 1 370 ? 113.989 -34.220 53.994 1.00 13.45 ? 372 PHE B CA 1 ATOM 6114 C C . PHE B 1 370 ? 113.735 -32.996 54.868 1.00 13.12 ? 372 PHE B C 1 ATOM 6115 O O . PHE B 1 370 ? 113.434 -33.122 56.056 1.00 13.62 ? 372 PHE B O 1 ATOM 6116 C CB . PHE B 1 370 ? 115.492 -34.384 53.753 1.00 13.73 ? 372 PHE B CB 1 ATOM 6117 C CG . PHE B 1 370 ? 116.272 -34.741 54.988 1.00 13.85 ? 372 PHE B CG 1 ATOM 6118 C CD1 . PHE B 1 370 ? 116.261 -36.037 55.481 1.00 13.94 ? 372 PHE B CD1 1 ATOM 6119 C CD2 . PHE B 1 370 ? 117.031 -33.786 55.644 1.00 14.07 ? 372 PHE B CD2 1 ATOM 6120 C CE1 . PHE B 1 370 ? 116.985 -36.369 56.615 1.00 14.39 ? 372 PHE B CE1 1 ATOM 6121 C CE2 . PHE B 1 370 ? 117.755 -34.111 56.778 1.00 14.03 ? 372 PHE B CE2 1 ATOM 6122 C CZ . PHE B 1 370 ? 117.733 -35.405 57.263 1.00 13.84 ? 372 PHE B CZ 1 ATOM 6123 N N . LEU B 1 371 ? 113.848 -31.816 54.269 1.00 12.36 ? 373 LEU B N 1 ATOM 6124 C CA . LEU B 1 371 ? 113.616 -30.567 54.986 1.00 12.97 ? 373 LEU B CA 1 ATOM 6125 C C . LEU B 1 371 ? 112.200 -30.511 55.560 1.00 12.87 ? 373 LEU B C 1 ATOM 6126 O O . LEU B 1 371 ? 112.002 -30.088 56.696 1.00 13.66 ? 373 LEU B O 1 ATOM 6127 C CB . LEU B 1 371 ? 113.870 -29.363 54.075 1.00 12.14 ? 373 LEU B CB 1 ATOM 6128 C CG . LEU B 1 371 ? 115.271 -28.744 54.058 1.00 12.46 ? 373 LEU B CG 1 ATOM 6129 C CD1 . LEU B 1 371 ? 116.347 -29.806 53.885 1.00 12.36 ? 373 LEU B CD1 1 ATOM 6130 C CD2 . LEU B 1 371 ? 115.383 -27.686 52.970 1.00 11.92 ? 373 LEU B CD2 1 ATOM 6131 N N . GLN B 1 372 ? 111.222 -30.960 54.780 1.00 13.41 ? 374 GLN B N 1 ATOM 6132 C CA . GLN B 1 372 ? 109.830 -30.937 55.224 1.00 14.38 ? 374 GLN B CA 1 ATOM 6133 C C . GLN B 1 372 ? 109.568 -31.939 56.346 1.00 14.91 ? 374 GLN B C 1 ATOM 6134 O O . GLN B 1 372 ? 109.031 -31.577 57.393 1.00 15.10 ? 374 GLN B O 1 ATOM 6135 C CB . GLN B 1 372 ? 108.876 -31.187 54.053 1.00 14.57 ? 374 GLN B CB 1 ATOM 6136 C CG . GLN B 1 372 ? 107.399 -31.091 54.417 1.00 14.29 ? 374 GLN B CG 1 ATOM 6137 C CD . GLN B 1 372 ? 106.943 -29.665 54.674 1.00 15.23 ? 374 GLN B CD 1 ATOM 6138 O OE1 . GLN B 1 372 ? 107.034 -28.805 53.798 1.00 15.24 ? 374 GLN B OE1 1 ATOM 6139 N NE2 . GLN B 1 372 ? 106.408 -29.419 55.866 1.00 14.50 ? 374 GLN B NE2 1 ATOM 6140 N N . GLN B 1 373 ? 109.960 -33.192 56.127 1.00 14.75 ? 375 GLN B N 1 ATOM 6141 C CA . GLN B 1 373 ? 109.581 -34.281 57.028 1.00 15.72 ? 375 GLN B CA 1 ATOM 6142 C C . GLN B 1 373 ? 110.451 -34.344 58.279 1.00 16.16 ? 375 GLN B C 1 ATOM 6143 O O . GLN B 1 373 ? 109.941 -34.484 59.388 1.00 16.34 ? 375 GLN B O 1 ATOM 6144 C CB . GLN B 1 373 ? 109.619 -35.632 56.307 1.00 15.98 ? 375 GLN B CB 1 ATOM 6145 C CG . GLN B 1 373 ? 109.331 -36.814 57.222 1.00 17.72 ? 375 GLN B CG 1 ATOM 6146 C CD . GLN B 1 373 ? 109.393 -38.152 56.508 1.00 18.07 ? 375 GLN B CD 1 ATOM 6147 O OE1 . GLN B 1 373 ? 108.585 -39.045 56.766 1.00 20.49 ? 375 GLN B OE1 1 ATOM 6148 N NE2 . GLN B 1 373 ? 110.375 -38.310 55.634 1.00 17.72 ? 375 GLN B NE2 1 ATOM 6149 N N . THR B 1 374 ? 111.766 -34.281 58.090 1.00 15.19 ? 376 THR B N 1 ATOM 6150 C CA . THR B 1 374 ? 112.706 -34.598 59.161 1.00 15.10 ? 376 THR B CA 1 ATOM 6151 C C . THR B 1 374 ? 113.103 -33.369 59.975 1.00 14.72 ? 376 THR B C 1 ATOM 6152 O O . THR B 1 374 ? 113.513 -33.485 61.132 1.00 15.03 ? 376 THR B O 1 ATOM 6153 C CB . THR B 1 374 ? 113.963 -35.293 58.607 1.00 15.53 ? 376 THR B CB 1 ATOM 6154 O OG1 . THR B 1 374 ? 113.577 -36.491 57.921 1.00 15.66 ? 376 THR B OG1 1 ATOM 6155 C CG2 . THR B 1 374 ? 114.933 -35.641 59.732 1.00 15.64 ? 376 THR B CG2 1 ATOM 6156 N N . TRP B 1 375 ? 112.961 -32.190 59.374 1.00 13.69 ? 377 TRP B N 1 ATOM 6157 C CA . TRP B 1 375 ? 113.337 -30.948 60.038 1.00 13.18 ? 377 TRP B CA 1 ATOM 6158 C C . TRP B 1 375 ? 112.122 -30.094 60.412 1.00 13.36 ? 377 TRP B C 1 ATOM 6159 O O . TRP B 1 375 ? 111.838 -29.890 61.596 1.00 12.06 ? 377 TRP B O 1 ATOM 6160 C CB . TRP B 1 375 ? 114.326 -30.148 59.181 1.00 13.10 ? 377 TRP B CB 1 ATOM 6161 C CG . TRP B 1 375 ? 115.697 -30.768 59.091 1.00 13.47 ? 377 TRP B CG 1 ATOM 6162 C CD1 . TRP B 1 375 ? 116.138 -31.885 59.742 1.00 14.20 ? 377 TRP B CD1 1 ATOM 6163 C CD2 . TRP B 1 375 ? 116.815 -30.280 58.333 1.00 13.36 ? 377 TRP B CD2 1 ATOM 6164 N NE1 . TRP B 1 375 ? 117.452 -32.136 59.419 1.00 13.84 ? 377 TRP B NE1 1 ATOM 6165 C CE2 . TRP B 1 375 ? 117.891 -31.164 58.558 1.00 13.59 ? 377 TRP B CE2 1 ATOM 6166 C CE3 . TRP B 1 375 ? 117.009 -29.184 57.487 1.00 12.93 ? 377 TRP B CE3 1 ATOM 6167 C CZ2 . TRP B 1 375 ? 119.143 -30.980 57.973 1.00 13.56 ? 377 TRP B CZ2 1 ATOM 6168 C CZ3 . TRP B 1 375 ? 118.248 -29.008 56.899 1.00 13.06 ? 377 TRP B CZ3 1 ATOM 6169 C CH2 . TRP B 1 375 ? 119.298 -29.905 57.141 1.00 13.26 ? 377 TRP B CH2 1 ATOM 6170 N N . ALA B 1 376 ? 111.398 -29.612 59.406 1.00 12.68 ? 378 ALA B N 1 ATOM 6171 C CA . ALA B 1 376 ? 110.265 -28.718 59.641 1.00 13.38 ? 378 ALA B CA 1 ATOM 6172 C C . ALA B 1 376 ? 109.160 -29.375 60.471 1.00 13.53 ? 378 ALA B C 1 ATOM 6173 O O . ALA B 1 376 ? 108.640 -28.774 61.409 1.00 15.42 ? 378 ALA B O 1 ATOM 6174 C CB . ALA B 1 376 ? 109.704 -28.211 58.322 1.00 13.03 ? 378 ALA B CB 1 ATOM 6175 N N . ASP B 1 377 ? 108.800 -30.604 60.110 1.00 14.10 ? 379 ASP B N 1 ATOM 6176 C CA . ASP B 1 377 ? 107.684 -31.303 60.741 1.00 14.94 ? 379 ASP B CA 1 ATOM 6177 C C . ASP B 1 377 ? 108.107 -31.999 62.033 1.00 15.39 ? 379 ASP B C 1 ATOM 6178 O O . ASP B 1 377 ? 107.322 -32.730 62.639 1.00 16.06 ? 379 ASP B O 1 ATOM 6179 C CB . ASP B 1 377 ? 107.091 -32.338 59.781 1.00 14.98 ? 379 ASP B CB 1 ATOM 6180 C CG . ASP B 1 377 ? 106.310 -31.705 58.645 1.00 15.34 ? 379 ASP B CG 1 ATOM 6181 O OD1 . ASP B 1 377 ? 106.319 -30.462 58.530 1.00 14.72 ? 379 ASP B OD1 1 ATOM 6182 O OD2 . ASP B 1 377 ? 105.701 -32.459 57.856 1.00 16.22 ? 379 ASP B OD2 1 ATOM 6183 N N . ASN B 1 378 ? 109.361 -31.802 62.424 1.00 15.27 ? 380 ASN B N 1 ATOM 6184 C CA . ASN B 1 378 ? 109.958 -32.563 63.518 1.00 15.78 ? 380 ASN B CA 1 ATOM 6185 C C . ASN B 1 378 ? 110.089 -31.720 64.781 1.00 15.99 ? 380 ASN B C 1 ATOM 6186 O O . ASN B 1 378 ? 110.920 -30.815 64.847 1.00 15.41 ? 380 ASN B O 1 ATOM 6187 C CB . ASN B 1 378 ? 111.329 -33.099 63.092 1.00 15.56 ? 380 ASN B CB 1 ATOM 6188 C CG . ASN B 1 378 ? 111.923 -34.064 64.101 1.00 16.59 ? 380 ASN B CG 1 ATOM 6189 O OD1 . ASN B 1 378 ? 111.422 -34.203 65.217 1.00 16.59 ? 380 ASN B OD1 1 ATOM 6190 N ND2 . ASN B 1 378 ? 113.016 -34.717 63.720 1.00 14.29 ? 380 ASN B ND2 1 ATOM 6191 N N . ALA B 1 379 ? 109.265 -32.023 65.781 1.00 16.85 ? 381 ALA B N 1 ATOM 6192 C CA . ALA B 1 379 ? 109.200 -31.222 67.003 1.00 16.79 ? 381 ALA B CA 1 ATOM 6193 C C . ALA B 1 379 ? 110.506 -31.258 67.787 1.00 18.26 ? 381 ALA B C 1 ATOM 6194 O O . ALA B 1 379 ? 110.734 -30.433 68.674 1.00 18.74 ? 381 ALA B O 1 ATOM 6195 C CB . ALA B 1 379 ? 108.046 -31.685 67.881 1.00 17.84 ? 381 ALA B CB 1 ATOM 6196 N N . ASN B 1 380 ? 111.358 -32.224 67.467 1.00 18.75 ? 382 ASN B N 1 ATOM 6197 C CA . ASN B 1 380 ? 112.599 -32.418 68.207 1.00 19.48 ? 382 ASN B CA 1 ATOM 6198 C C . ASN B 1 380 ? 113.837 -32.091 67.384 1.00 19.43 ? 382 ASN B C 1 ATOM 6199 O O . ASN B 1 380 ? 114.936 -32.570 67.676 1.00 19.32 ? 382 ASN B O 1 ATOM 6200 C CB . ASN B 1 380 ? 112.669 -33.845 68.737 1.00 21.44 ? 382 ASN B CB 1 ATOM 6201 C CG . ASN B 1 380 ? 111.480 -34.192 69.606 1.00 21.47 ? 382 ASN B CG 1 ATOM 6202 O OD1 . ASN B 1 380 ? 110.702 -35.087 69.283 1.00 22.83 ? 382 ASN B OD1 1 ATOM 6203 N ND2 . ASN B 1 380 ? 111.299 -33.437 70.684 1.00 21.56 ? 382 ASN B ND2 1 ATOM 6204 N N . PHE B 1 381 ? 113.645 -31.283 66.346 1.00 17.40 ? 383 PHE B N 1 ATOM 6205 C CA . PHE B 1 381 ? 114.750 -30.748 65.560 1.00 17.08 ? 383 PHE B CA 1 ATOM 6206 C C . PHE B 1 381 ? 114.745 -29.222 65.645 1.00 16.81 ? 383 PHE B C 1 ATOM 6207 O O . PHE B 1 381 ? 113.689 -28.601 65.549 1.00 17.94 ? 383 PHE B O 1 ATOM 6208 C CB . PHE B 1 381 ? 114.630 -31.194 64.098 1.00 16.05 ? 383 PHE B CB 1 ATOM 6209 C CG . PHE B 1 381 ? 115.795 -30.781 63.248 1.00 16.39 ? 383 PHE B CG 1 ATOM 6210 C CD1 . PHE B 1 381 ? 116.922 -31.581 63.164 1.00 15.92 ? 383 PHE B CD1 1 ATOM 6211 C CD2 . PHE B 1 381 ? 115.809 -29.541 62.627 1.00 16.97 ? 383 PHE B CD2 1 ATOM 6212 C CE1 . PHE B 1 381 ? 118.026 -31.175 62.441 1.00 16.17 ? 383 PHE B CE1 1 ATOM 6213 C CE2 . PHE B 1 381 ? 116.908 -29.130 61.895 1.00 16.48 ? 383 PHE B CE2 1 ATOM 6214 C CZ . PHE B 1 381 ? 118.020 -29.949 61.804 1.00 16.16 ? 383 PHE B CZ 1 ATOM 6215 N N . PRO B 1 382 ? 115.917 -28.617 65.819 1.00 16.77 ? 384 PRO B N 1 ATOM 6216 C CA . PRO B 1 382 ? 117.190 -29.334 65.804 1.00 17.22 ? 384 PRO B CA 1 ATOM 6217 C C . PRO B 1 382 ? 117.479 -30.060 67.117 1.00 18.57 ? 384 PRO B C 1 ATOM 6218 O O . PRO B 1 382 ? 116.783 -29.842 68.109 1.00 18.85 ? 384 PRO B O 1 ATOM 6219 C CB . PRO B 1 382 ? 118.213 -28.215 65.595 1.00 17.74 ? 384 PRO B CB 1 ATOM 6220 C CG . PRO B 1 382 ? 117.551 -26.993 66.135 1.00 17.52 ? 384 PRO B CG 1 ATOM 6221 C CD . PRO B 1 382 ? 116.102 -27.157 65.783 1.00 16.60 ? 384 PRO B CD 1 ATOM 6222 N N . PRO B 1 383 ? 118.519 -30.908 67.124 1.00 19.43 ? 385 PRO B N 1 ATOM 6223 C CA . PRO B 1 383 ? 118.907 -31.699 68.286 1.00 19.81 ? 385 PRO B CA 1 ATOM 6224 C C . PRO B 1 383 ? 119.734 -30.889 69.278 1.00 21.01 ? 385 PRO B C 1 ATOM 6225 O O . PRO B 1 383 ? 120.295 -29.851 68.919 1.00 21.05 ? 385 PRO B O 1 ATOM 6226 C CB . PRO B 1 383 ? 119.771 -32.803 67.674 1.00 20.09 ? 385 PRO B CB 1 ATOM 6227 C CG . PRO B 1 383 ? 120.397 -32.154 66.486 1.00 19.70 ? 385 PRO B CG 1 ATOM 6228 C CD . PRO B 1 383 ? 119.367 -31.191 65.952 1.00 19.60 ? 385 PRO B CD 1 ATOM 6229 N N . GLY B 1 384 ? 119.812 -31.367 70.516 1.00 22.26 ? 386 GLY B N 1 ATOM 6230 C CA . GLY B 1 384 ? 120.764 -30.832 71.487 1.00 21.11 ? 386 GLY B CA 1 ATOM 6231 C C . GLY B 1 384 ? 120.372 -29.491 72.077 1.00 21.87 ? 386 GLY B C 1 ATOM 6232 O O . GLY B 1 384 ? 121.214 -28.773 72.623 1.00 19.97 ? 386 GLY B O 1 ATOM 6233 N N . LYS B 1 385 ? 119.088 -29.157 71.990 1.00 21.33 ? 387 LYS B N 1 ATOM 6234 C CA . LYS B 1 385 ? 118.599 -27.890 72.524 1.00 21.40 ? 387 LYS B CA 1 ATOM 6235 C C . LYS B 1 385 ? 117.964 -28.056 73.906 1.00 21.63 ? 387 LYS B C 1 ATOM 6236 O O . LYS B 1 385 ? 117.616 -29.162 74.315 1.00 21.39 ? 387 LYS B O 1 ATOM 6237 C CB . LYS B 1 385 ? 117.610 -27.236 71.553 1.00 20.58 ? 387 LYS B CB 1 ATOM 6238 C CG . LYS B 1 385 ? 118.180 -26.973 70.166 1.00 19.70 ? 387 LYS B CG 1 ATOM 6239 C CD . LYS B 1 385 ? 119.430 -26.107 70.226 1.00 19.09 ? 387 LYS B CD 1 ATOM 6240 C CE . LYS B 1 385 ? 119.910 -25.728 68.833 1.00 17.61 ? 387 LYS B CE 1 ATOM 6241 N NZ . LYS B 1 385 ? 121.144 -24.894 68.866 1.00 16.34 ? 387 LYS B NZ 1 ATOM 6242 N N . THR B 1 386 ? 117.853 -26.950 74.633 1.00 23.44 ? 388 THR B N 1 ATOM 6243 C CA . THR B 1 386 ? 117.146 -26.941 75.909 1.00 26.45 ? 388 THR B CA 1 ATOM 6244 C C . THR B 1 386 ? 116.273 -25.696 75.990 1.00 24.61 ? 388 THR B C 1 ATOM 6245 O O . THR B 1 386 ? 116.767 -24.583 75.819 1.00 25.39 ? 388 THR B O 1 ATOM 6246 C CB . THR B 1 386 ? 118.129 -26.943 77.100 1.00 28.29 ? 388 THR B CB 1 ATOM 6247 O OG1 . THR B 1 386 ? 118.820 -28.199 77.159 1.00 30.72 ? 388 THR B OG1 1 ATOM 6248 C CG2 . THR B 1 386 ? 117.378 -26.725 78.408 1.00 29.94 ? 388 THR B CG2 1 ATOM 6249 N N . PRO B 1 387 ? 114.969 -25.879 76.190 1.00 24.97 ? 389 PRO B N 1 ATOM 6250 C CA . PRO B 1 387 ? 114.346 -27.204 76.280 1.00 25.87 ? 389 PRO B CA 1 ATOM 6251 C C . PRO B 1 387 ? 114.464 -28.015 74.989 1.00 25.90 ? 389 PRO B C 1 ATOM 6252 O O . PRO B 1 387 ? 114.538 -27.442 73.902 1.00 27.76 ? 389 PRO B O 1 ATOM 6253 C CB . PRO B 1 387 ? 112.869 -26.880 76.544 1.00 25.67 ? 389 PRO B CB 1 ATOM 6254 C CG . PRO B 1 387 ? 112.855 -25.481 77.058 1.00 24.40 ? 389 PRO B CG 1 ATOM 6255 C CD . PRO B 1 387 ? 113.996 -24.792 76.378 1.00 25.14 ? 389 PRO B CD 1 ATOM 6256 N N . ALA B 1 388 ? 114.398 -29.338 75.114 1.00 26.13 ? 390 ALA B N 1 ATOM 6257 C CA . ALA B 1 388 ? 114.650 -30.239 73.994 1.00 25.00 ? 390 ALA B CA 1 ATOM 6258 C C . ALA B 1 388 ? 113.603 -30.108 72.891 1.00 25.92 ? 390 ALA B C 1 ATOM 6259 O O . ALA B 1 388 ? 113.933 -30.124 71.705 1.00 24.04 ? 390 ALA B O 1 ATOM 6260 C CB . ALA B 1 388 ? 114.732 -31.677 74.478 1.00 25.03 ? 390 ALA B CB 1 ATOM 6261 N N . THR B 1 389 ? 112.339 -29.993 73.283 1.00 26.43 ? 391 THR B N 1 ATOM 6262 C CA . THR B 1 389 ? 111.257 -29.884 72.311 1.00 25.15 ? 391 THR B CA 1 ATOM 6263 C C . THR B 1 389 ? 111.219 -28.504 71.666 1.00 24.14 ? 391 THR B C 1 ATOM 6264 O O . THR B 1 389 ? 110.816 -27.520 72.288 1.00 23.76 ? 391 THR B O 1 ATOM 6265 C CB . THR B 1 389 ? 109.890 -30.220 72.932 1.00 25.73 ? 391 THR B CB 1 ATOM 6266 O OG1 . THR B 1 389 ? 109.872 -31.599 73.313 1.00 25.04 ? 391 THR B OG1 1 ATOM 6267 C CG2 . THR B 1 389 ? 108.776 -29.970 71.929 1.00 24.18 ? 391 THR B CG2 1 ATOM 6268 N N . VAL B 1 390 ? 111.654 -28.443 70.413 1.00 21.76 ? 392 VAL B N 1 ATOM 6269 C CA . VAL B 1 390 ? 111.687 -27.197 69.666 1.00 20.81 ? 392 VAL B CA 1 ATOM 6270 C C . VAL B 1 390 ? 110.284 -26.793 69.216 1.00 19.48 ? 392 VAL B C 1 ATOM 6271 O O . VAL B 1 390 ? 109.943 -25.611 69.200 1.00 19.29 ? 392 VAL B O 1 ATOM 6272 C CB . VAL B 1 390 ? 112.602 -27.324 68.431 1.00 21.07 ? 392 VAL B CB 1 ATOM 6273 C CG1 . VAL B 1 390 ? 112.477 -26.099 67.540 1.00 19.96 ? 392 VAL B CG1 1 ATOM 6274 C CG2 . VAL B 1 390 ? 114.045 -27.533 68.867 1.00 22.49 ? 392 VAL B CG2 1 ATOM 6275 N N . GLY B 1 391 ? 109.464 -27.785 68.886 1.00 19.65 ? 393 GLY B N 1 ATOM 6276 C CA . GLY B 1 391 ? 108.197 -27.538 68.210 1.00 20.06 ? 393 GLY B CA 1 ATOM 6277 C C . GLY B 1 391 ? 108.353 -27.583 66.700 1.00 19.65 ? 393 GLY B C 1 ATOM 6278 O O . GLY B 1 391 ? 109.440 -27.860 66.188 1.00 17.94 ? 393 GLY B O 1 ATOM 6279 N N . LEU B 1 392 ? 107.265 -27.310 65.987 1.00 18.16 ? 394 LEU B N 1 ATOM 6280 C CA . LEU B 1 392 ? 107.269 -27.383 64.528 1.00 17.29 ? 394 LEU B CA 1 ATOM 6281 C C . LEU B 1 392 ? 107.626 -26.040 63.891 1.00 16.30 ? 394 LEU B C 1 ATOM 6282 O O . LEU B 1 392 ? 107.540 -24.991 64.533 1.00 16.58 ? 394 LEU B O 1 ATOM 6283 C CB . LEU B 1 392 ? 105.910 -27.865 64.014 1.00 16.67 ? 394 LEU B CB 1 ATOM 6284 C CG . LEU B 1 392 ? 105.398 -29.205 64.548 1.00 17.64 ? 394 LEU B CG 1 ATOM 6285 C CD1 . LEU B 1 392 ? 104.208 -29.688 63.735 1.00 18.59 ? 394 LEU B CD1 1 ATOM 6286 C CD2 . LEU B 1 392 ? 106.501 -30.251 64.560 1.00 16.65 ? 394 LEU B CD2 1 ATOM 6287 N N . ASP B 1 393 ? 108.041 -26.085 62.628 1.00 15.62 ? 395 ASP B N 1 ATOM 6288 C CA . ASP B 1 393 ? 108.185 -24.886 61.809 1.00 14.62 ? 395 ASP B CA 1 ATOM 6289 C C . ASP B 1 393 ? 106.846 -24.153 61.750 1.00 14.35 ? 395 ASP B C 1 ATOM 6290 O O . ASP B 1 393 ? 105.843 -24.733 61.349 1.00 14.60 ? 395 ASP B O 1 ATOM 6291 C CB . ASP B 1 393 ? 108.628 -25.276 60.394 1.00 14.06 ? 395 ASP B CB 1 ATOM 6292 C CG . ASP B 1 393 ? 109.000 -24.076 59.536 1.00 14.34 ? 395 ASP B CG 1 ATOM 6293 O OD1 . ASP B 1 393 ? 108.185 -23.136 59.421 1.00 14.78 ? 395 ASP B OD1 1 ATOM 6294 O OD2 . ASP B 1 393 ? 110.096 -24.094 58.935 1.00 14.77 ? 395 ASP B OD2 1 ATOM 6295 N N . PRO B 1 394 ? 106.823 -22.881 62.176 1.00 14.01 ? 396 PRO B N 1 ATOM 6296 C CA . PRO B 1 394 ? 105.561 -22.141 62.237 1.00 14.56 ? 396 PRO B CA 1 ATOM 6297 C C . PRO B 1 394 ? 105.049 -21.752 60.850 1.00 15.49 ? 396 PRO B C 1 ATOM 6298 O O . PRO B 1 394 ? 103.856 -21.489 60.679 1.00 17.02 ? 396 PRO B O 1 ATOM 6299 C CB . PRO B 1 394 ? 105.927 -20.890 63.039 1.00 14.72 ? 396 PRO B CB 1 ATOM 6300 C CG . PRO B 1 394 ? 107.383 -20.698 62.791 1.00 14.08 ? 396 PRO B CG 1 ATOM 6301 C CD . PRO B 1 394 ? 107.966 -22.076 62.643 1.00 13.84 ? 396 PRO B CD 1 ATOM 6302 N N . ILE B 1 395 ? 105.944 -21.726 59.869 1.00 15.50 ? 397 ILE B N 1 ATOM 6303 C CA . ILE B 1 395 ? 105.564 -21.369 58.506 1.00 15.68 ? 397 ILE B CA 1 ATOM 6304 C C . ILE B 1 395 ? 105.052 -22.576 57.724 1.00 15.40 ? 397 ILE B C 1 ATOM 6305 O O . ILE B 1 395 ? 103.937 -22.551 57.205 1.00 17.65 ? 397 ILE B O 1 ATOM 6306 C CB . ILE B 1 395 ? 106.714 -20.672 57.751 1.00 15.33 ? 397 ILE B CB 1 ATOM 6307 C CG1 . ILE B 1 395 ? 107.151 -19.407 58.498 1.00 15.64 ? 397 ILE B CG1 1 ATOM 6308 C CG2 . ILE B 1 395 ? 106.299 -20.335 56.324 1.00 15.67 ? 397 ILE B CG2 1 ATOM 6309 C CD1 . ILE B 1 395 ? 106.006 -18.498 58.896 1.00 15.71 ? 397 ILE B CD1 1 ATOM 6310 N N . ILE B 1 396 ? 105.837 -23.649 57.686 1.00 15.42 ? 398 ILE B N 1 ATOM 6311 C CA . ILE B 1 396 ? 105.514 -24.790 56.831 1.00 14.44 ? 398 ILE B CA 1 ATOM 6312 C C . ILE B 1 396 ? 105.265 -26.084 57.598 1.00 14.20 ? 398 ILE B C 1 ATOM 6313 O O . ILE B 1 396 ? 104.859 -27.084 57.011 1.00 14.22 ? 398 ILE B O 1 ATOM 6314 C CB . ILE B 1 396 ? 106.606 -25.041 55.770 1.00 14.57 ? 398 ILE B CB 1 ATOM 6315 C CG1 . ILE B 1 396 ? 107.951 -25.340 56.440 1.00 14.17 ? 398 ILE B CG1 1 ATOM 6316 C CG2 . ILE B 1 396 ? 106.716 -23.854 54.826 1.00 13.77 ? 398 ILE B CG2 1 ATOM 6317 C CD1 . ILE B 1 396 ? 108.944 -26.024 55.523 1.00 14.49 ? 398 ILE B CD1 1 ATOM 6318 N N . GLY B 1 397 ? 105.491 -26.060 58.908 1.00 14.13 ? 399 GLY B N 1 ATOM 6319 C CA . GLY B 1 397 ? 105.279 -27.244 59.736 1.00 13.99 ? 399 GLY B CA 1 ATOM 6320 C C . GLY B 1 397 ? 103.869 -27.795 59.641 1.00 14.80 ? 399 GLY B C 1 ATOM 6321 O O . GLY B 1 397 ? 102.892 -27.058 59.786 1.00 15.44 ? 399 GLY B O 1 ATOM 6322 N N . GLN B 1 398 ? 103.763 -29.101 59.413 1.00 15.01 ? 400 GLN B N 1 ATOM 6323 C CA . GLN B 1 398 ? 102.467 -29.752 59.261 1.00 16.28 ? 400 GLN B CA 1 ATOM 6324 C C . GLN B 1 398 ? 102.257 -30.882 60.267 1.00 18.08 ? 400 GLN B C 1 ATOM 6325 O O . GLN B 1 398 ? 103.203 -31.572 60.652 1.00 16.87 ? 400 GLN B O 1 ATOM 6326 C CB . GLN B 1 398 ? 102.290 -30.273 57.832 1.00 16.01 ? 400 GLN B CB 1 ATOM 6327 C CG . GLN B 1 398 ? 102.155 -29.164 56.801 1.00 16.82 ? 400 GLN B CG 1 ATOM 6328 C CD . GLN B 1 398 ? 101.810 -29.674 55.417 1.00 17.72 ? 400 GLN B CD 1 ATOM 6329 O OE1 . GLN B 1 398 ? 101.316 -28.925 54.578 1.00 19.44 ? 400 GLN B OE1 1 ATOM 6330 N NE2 . GLN B 1 398 ? 102.063 -30.953 55.172 1.00 17.34 ? 400 GLN B NE2 1 ATOM 6331 N N . ASN B 1 399 ? 101.007 -31.063 60.684 1.00 18.40 ? 401 ASN B N 1 ATOM 6332 C CA . ASN B 1 399 ? 100.636 -32.159 61.571 1.00 21.06 ? 401 ASN B CA 1 ATOM 6333 C C . ASN B 1 399 ? 99.206 -32.625 61.315 1.00 22.11 ? 401 ASN B C 1 ATOM 6334 O O . ASN B 1 399 ? 98.332 -32.499 62.175 1.00 21.31 ? 401 ASN B O 1 ATOM 6335 C CB . ASN B 1 399 ? 100.813 -31.746 63.035 1.00 21.92 ? 401 ASN B CB 1 ATOM 6336 C CG . ASN B 1 399 ? 100.666 -32.914 63.993 1.00 23.61 ? 401 ASN B CG 1 ATOM 6337 O OD1 . ASN B 1 399 ? 100.939 -34.064 63.642 1.00 22.81 ? 401 ASN B OD1 1 ATOM 6338 N ND2 . ASN B 1 399 ? 100.246 -32.621 65.218 1.00 25.17 ? 401 ASN B ND2 1 ATOM 6339 N N . ASN B 1 400 ? 98.969 -33.131 60.109 1.00 21.48 ? 402 ASN B N 1 ATOM 6340 C CA . ASN B 1 400 ? 97.653 -33.620 59.718 1.00 23.70 ? 402 ASN B CA 1 ATOM 6341 C C . ASN B 1 400 ? 96.555 -32.573 59.884 1.00 24.07 ? 402 ASN B C 1 ATOM 6342 O O . ASN B 1 400 ? 95.421 -32.899 60.229 1.00 24.37 ? 402 ASN B O 1 ATOM 6343 C CB . ASN B 1 400 ? 97.304 -34.897 60.486 1.00 23.41 ? 402 ASN B CB 1 ATOM 6344 C CG . ASN B 1 400 ? 98.237 -36.047 60.154 1.00 25.05 ? 402 ASN B CG 1 ATOM 6345 O OD1 . ASN B 1 400 ? 98.308 -36.491 59.008 1.00 24.07 ? 402 ASN B OD1 1 ATOM 6346 N ND2 . ASN B 1 400 ? 98.969 -36.526 61.155 1.00 25.51 ? 402 ASN B ND2 1 ATOM 6347 N N . GLY B 1 401 ? 96.902 -31.314 59.636 1.00 23.81 ? 403 GLY B N 1 ATOM 6348 C CA . GLY B 1 401 ? 95.918 -30.238 59.599 1.00 23.43 ? 403 GLY B CA 1 ATOM 6349 C C . GLY B 1 401 ? 95.609 -29.662 60.968 1.00 24.81 ? 403 GLY B C 1 ATOM 6350 O O . GLY B 1 401 ? 94.877 -28.678 61.084 1.00 25.45 ? 403 GLY B O 1 ATOM 6351 N N . GLN B 1 402 ? 96.176 -30.271 62.007 1.00 23.93 ? 404 GLN B N 1 ATOM 6352 C CA . GLN B 1 402 ? 96.026 -29.773 63.373 1.00 26.18 ? 404 GLN B CA 1 ATOM 6353 C C . GLN B 1 402 ? 96.836 -28.498 63.593 1.00 24.55 ? 404 GLN B C 1 ATOM 6354 O O . GLN B 1 402 ? 97.815 -28.248 62.889 1.00 24.24 ? 404 GLN B O 1 ATOM 6355 C CB . GLN B 1 402 ? 96.457 -30.841 64.383 1.00 27.28 ? 404 GLN B CB 1 ATOM 6356 C CG . GLN B 1 402 ? 95.662 -32.132 64.298 1.00 28.92 ? 404 GLN B CG 1 ATOM 6357 C CD . GLN B 1 402 ? 94.206 -31.940 64.672 1.00 32.48 ? 404 GLN B CD 1 ATOM 6358 O OE1 . GLN B 1 402 ? 93.866 -31.824 65.850 1.00 36.76 ? 404 GLN B OE1 1 ATOM 6359 N NE2 . GLN B 1 402 ? 93.337 -31.897 63.668 1.00 34.26 ? 404 GLN B NE2 1 ATOM 6360 N N . PRO B 1 403 ? 96.441 -27.696 64.593 1.00 23.65 ? 405 PRO B N 1 ATOM 6361 C CA . PRO B 1 403 ? 97.275 -26.589 65.058 1.00 23.19 ? 405 PRO B CA 1 ATOM 6362 C C . PRO B 1 403 ? 98.678 -27.067 65.439 1.00 22.50 ? 405 PRO B C 1 ATOM 6363 O O . PRO B 1 403 ? 98.830 -28.153 65.994 1.00 23.92 ? 405 PRO B O 1 ATOM 6364 C CB . PRO B 1 403 ? 96.533 -26.088 66.303 1.00 24.85 ? 405 PRO B CB 1 ATOM 6365 C CG . PRO B 1 403 ? 95.125 -26.538 66.117 1.00 25.38 ? 405 PRO B CG 1 ATOM 6366 C CD . PRO B 1 403 ? 95.220 -27.853 65.402 1.00 24.44 ? 405 PRO B CD 1 ATOM 6367 N N . ARG B 1 404 ? 99.688 -26.263 65.121 1.00 20.53 ? 406 ARG B N 1 ATOM 6368 C CA . ARG B 1 404 ? 101.081 -26.635 65.350 1.00 19.96 ? 406 ARG B CA 1 ATOM 6369 C C . ARG B 1 404 ? 101.578 -26.059 66.671 1.00 19.49 ? 406 ARG B C 1 ATOM 6370 O O . ARG B 1 404 ? 101.460 -24.858 66.915 1.00 19.70 ? 406 ARG B O 1 ATOM 6371 C CB . ARG B 1 404 ? 101.964 -26.122 64.208 1.00 19.58 ? 406 ARG B CB 1 ATOM 6372 C CG . ARG B 1 404 ? 101.786 -26.856 62.885 1.00 18.07 ? 406 ARG B CG 1 ATOM 6373 C CD . ARG B 1 404 ? 100.708 -26.220 62.017 1.00 18.29 ? 406 ARG B CD 1 ATOM 6374 N NE . ARG B 1 404 ? 100.711 -24.760 62.099 1.00 17.27 ? 406 ARG B NE 1 ATOM 6375 C CZ . ARG B 1 404 ? 101.621 -23.976 61.529 1.00 17.03 ? 406 ARG B CZ 1 ATOM 6376 N NH1 . ARG B 1 404 ? 102.618 -24.505 60.832 1.00 16.80 ? 406 ARG B NH1 1 ATOM 6377 N NH2 . ARG B 1 404 ? 101.542 -22.658 61.666 1.00 16.89 ? 406 ARG B NH2 1 ATOM 6378 N N . VAL B 1 405 ? 102.144 -26.914 67.515 1.00 19.97 ? 407 VAL B N 1 ATOM 6379 C CA . VAL B 1 405 ? 102.791 -26.452 68.737 1.00 19.63 ? 407 VAL B CA 1 ATOM 6380 C C . VAL B 1 405 ? 104.223 -26.014 68.450 1.00 20.24 ? 407 VAL B C 1 ATOM 6381 O O . VAL B 1 405 ? 105.040 -26.803 67.974 1.00 21.39 ? 407 VAL B O 1 ATOM 6382 C CB . VAL B 1 405 ? 102.779 -27.533 69.836 1.00 20.34 ? 407 VAL B CB 1 ATOM 6383 C CG1 . VAL B 1 405 ? 103.508 -27.038 71.079 1.00 20.03 ? 407 VAL B CG1 1 ATOM 6384 C CG2 . VAL B 1 405 ? 101.346 -27.918 70.175 1.00 20.92 ? 407 VAL B CG2 1 ATOM 6385 N N . VAL B 1 406 ? 104.508 -24.742 68.713 1.00 19.47 ? 408 VAL B N 1 ATOM 6386 C CA . VAL B 1 406 ? 105.800 -24.153 68.389 1.00 19.96 ? 408 VAL B CA 1 ATOM 6387 C C . VAL B 1 406 ? 106.369 -23.438 69.612 1.00 21.79 ? 408 VAL B C 1 ATOM 6388 O O . VAL B 1 406 ? 105.698 -22.599 70.215 1.00 20.82 ? 408 VAL B O 1 ATOM 6389 C CB . VAL B 1 406 ? 105.674 -23.136 67.235 1.00 19.87 ? 408 VAL B CB 1 ATOM 6390 C CG1 . VAL B 1 406 ? 107.040 -22.589 66.854 1.00 18.52 ? 408 VAL B CG1 1 ATOM 6391 C CG2 . VAL B 1 406 ? 104.996 -23.778 66.033 1.00 19.25 ? 408 VAL B CG2 1 ATOM 6392 N N . ASN B 1 407 ? 107.606 -23.769 69.975 1.00 21.27 ? 409 ASN B N 1 ATOM 6393 C CA . ASN B 1 407 ? 108.244 -23.176 71.149 1.00 22.40 ? 409 ASN B CA 1 ATOM 6394 C C . ASN B 1 407 ? 109.356 -22.189 70.794 1.00 22.64 ? 409 ASN B C 1 ATOM 6395 O O . ASN B 1 407 ? 109.921 -22.238 69.699 1.00 21.80 ? 409 ASN B O 1 ATOM 6396 C CB . ASN B 1 407 ? 108.789 -24.270 72.078 1.00 22.92 ? 409 ASN B CB 1 ATOM 6397 C CG . ASN B 1 407 ? 107.737 -25.296 72.452 1.00 23.93 ? 409 ASN B CG 1 ATOM 6398 O OD1 . ASN B 1 407 ? 108.019 -26.491 72.532 1.00 24.36 ? 409 ASN B OD1 1 ATOM 6399 N ND2 . ASN B 1 407 ? 106.512 -24.836 72.663 1.00 24.12 ? 409 ASN B ND2 1 ATOM 6400 N N . GLY B 1 408 ? 109.658 -21.285 71.723 1.00 22.56 ? 410 GLY B N 1 ATOM 6401 C CA . GLY B 1 408 ? 110.832 -20.424 71.605 1.00 20.93 ? 410 GLY B CA 1 ATOM 6402 C C . GLY B 1 408 ? 110.567 -19.072 70.966 1.00 20.65 ? 410 GLY B C 1 ATOM 6403 O O . GLY B 1 408 ? 111.445 -18.210 70.941 1.00 19.81 ? 410 GLY B O 1 ATOM 6404 N N . LEU B 1 409 ? 109.355 -18.880 70.452 1.00 21.51 ? 411 LEU B N 1 ATOM 6405 C CA . LEU B 1 409 ? 109.035 -17.680 69.676 1.00 21.35 ? 411 LEU B CA 1 ATOM 6406 C C . LEU B 1 409 ? 109.015 -16.412 70.530 1.00 23.32 ? 411 LEU B C 1 ATOM 6407 O O . LEU B 1 409 ? 109.319 -15.321 70.045 1.00 23.12 ? 411 LEU B O 1 ATOM 6408 C CB . LEU B 1 409 ? 107.695 -17.848 68.957 1.00 20.34 ? 411 LEU B CB 1 ATOM 6409 C CG . LEU B 1 409 ? 107.639 -18.944 67.892 1.00 19.57 ? 411 LEU B CG 1 ATOM 6410 C CD1 . LEU B 1 409 ? 106.223 -19.088 67.356 1.00 19.07 ? 411 LEU B CD1 1 ATOM 6411 C CD2 . LEU B 1 409 ? 108.620 -18.648 66.767 1.00 19.61 ? 411 LEU B CD2 1 ATOM 6412 N N . LEU B 1 410 ? 108.656 -16.565 71.800 1.00 26.04 ? 412 LEU B N 1 ATOM 6413 C CA . LEU B 1 410 ? 108.527 -15.429 72.707 1.00 29.34 ? 412 LEU B CA 1 ATOM 6414 C C . LEU B 1 410 ? 109.814 -15.210 73.496 1.00 30.40 ? 412 LEU B C 1 ATOM 6415 O O . LEU B 1 410 ? 110.192 -16.042 74.319 1.00 29.94 ? 412 LEU B O 1 ATOM 6416 C CB . LEU B 1 410 ? 107.347 -15.640 73.658 1.00 31.36 ? 412 LEU B CB 1 ATOM 6417 C CG . LEU B 1 410 ? 106.024 -15.992 72.972 1.00 31.70 ? 412 LEU B CG 1 ATOM 6418 C CD1 . LEU B 1 410 ? 105.029 -16.582 73.961 1.00 34.20 ? 412 LEU B CD1 1 ATOM 6419 C CD2 . LEU B 1 410 ? 105.443 -14.773 72.272 1.00 31.56 ? 412 LEU B CD2 1 ATOM 6420 N N . PRO B 1 411 ? 110.480 -14.073 73.248 1.00 29.16 ? 413 PRO B N 1 ATOM 6421 C CA . PRO B 1 411 ? 111.872 -13.811 73.613 1.00 32.45 ? 413 PRO B CA 1 ATOM 6422 C C . PRO B 1 411 ? 112.163 -13.851 75.115 1.00 35.41 ? 413 PRO B C 1 ATOM 6423 O O . PRO B 1 411 ? 113.322 -13.730 75.513 1.00 36.92 ? 413 PRO B O 1 ATOM 6424 C CB . PRO B 1 411 ? 112.113 -12.398 73.076 1.00 31.19 ? 413 PRO B CB 1 ATOM 6425 C CG . PRO B 1 411 ? 111.147 -12.256 71.950 1.00 30.19 ? 413 PRO B CG 1 ATOM 6426 C CD . PRO B 1 411 ? 109.929 -13.017 72.380 1.00 28.36 ? 413 PRO B CD 1 ATOM 6427 N N . SER B 1 412 ? 111.134 -14.023 75.938 1.00 33.98 ? 414 SER B N 1 ATOM 6428 C CA . SER B 1 412 ? 111.298 -13.872 77.381 1.00 36.97 ? 414 SER B CA 1 ATOM 6429 C C . SER B 1 412 ? 110.829 -15.092 78.173 1.00 38.03 ? 414 SER B C 1 ATOM 6430 O O . SER B 1 412 ? 110.821 -15.077 79.404 1.00 37.75 ? 414 SER B O 1 ATOM 6431 C CB . SER B 1 412 ? 110.591 -12.607 77.875 1.00 39.42 ? 414 SER B CB 1 ATOM 6432 O OG . SER B 1 412 ? 109.195 -12.679 77.647 1.00 36.35 ? 414 SER B OG 1 ATOM 6433 N N . ASN B 1 413 ? 110.436 -16.144 77.462 1.00 34.81 ? 415 ASN B N 1 ATOM 6434 C CA . ASN B 1 413 ? 110.264 -17.461 78.068 1.00 35.26 ? 415 ASN B CA 1 ATOM 6435 C C . ASN B 1 413 ? 110.333 -18.557 77.010 1.00 32.86 ? 415 ASN B C 1 ATOM 6436 O O . ASN B 1 413 ? 109.306 -19.065 76.554 1.00 29.39 ? 415 ASN B O 1 ATOM 6437 C CB . ASN B 1 413 ? 108.944 -17.540 78.846 1.00 35.16 ? 415 ASN B CB 1 ATOM 6438 C CG . ASN B 1 413 ? 108.772 -18.862 79.575 1.00 36.77 ? 415 ASN B CG 1 ATOM 6439 O OD1 . ASN B 1 413 ? 109.647 -19.727 79.532 1.00 37.00 ? 415 ASN B OD1 1 ATOM 6440 N ND2 . ASN B 1 413 ? 107.636 -19.026 80.248 1.00 36.69 ? 415 ASN B ND2 1 ATOM 6441 N N . SER B 1 414 ? 111.553 -18.906 76.616 1.00 30.40 ? 416 SER B N 1 ATOM 6442 C CA . SER B 1 414 ? 111.770 -19.869 75.544 1.00 28.31 ? 416 SER B CA 1 ATOM 6443 C C . SER B 1 414 ? 110.979 -21.144 75.785 1.00 28.98 ? 416 SER B C 1 ATOM 6444 O O . SER B 1 414 ? 110.812 -21.962 74.881 1.00 27.84 ? 416 SER B O 1 ATOM 6445 C CB . SER B 1 414 ? 113.259 -20.190 75.403 1.00 29.97 ? 416 SER B CB 1 ATOM 6446 O OG . SER B 1 414 ? 113.723 -20.961 76.497 1.00 31.84 ? 416 SER B OG 1 ATOM 6447 N N . SER B 1 415 ? 110.480 -21.299 77.008 1.00 29.74 ? 417 SER B N 1 ATOM 6448 C CA . SER B 1 415 ? 109.621 -22.424 77.355 1.00 28.85 ? 417 SER B CA 1 ATOM 6449 C C . SER B 1 415 ? 108.172 -22.180 76.937 1.00 27.78 ? 417 SER B C 1 ATOM 6450 O O . SER B 1 415 ? 107.378 -23.117 76.844 1.00 28.56 ? 417 SER B O 1 ATOM 6451 C CB . SER B 1 415 ? 109.696 -22.709 78.857 1.00 30.86 ? 417 SER B CB 1 ATOM 6452 O OG . SER B 1 415 ? 110.649 -23.719 79.138 1.00 30.29 ? 417 SER B OG 1 ATOM 6453 N N . ALA B 1 416 ? 107.835 -20.920 76.679 1.00 27.16 ? 418 ALA B N 1 ATOM 6454 C CA . ALA B 1 416 ? 106.471 -20.552 76.314 1.00 26.95 ? 418 ALA B CA 1 ATOM 6455 C C . ALA B 1 416 ? 106.087 -21.112 74.946 1.00 28.14 ? 418 ALA B C 1 ATOM 6456 O O . ALA B 1 416 ? 106.749 -20.836 73.947 1.00 28.75 ? 418 ALA B O 1 ATOM 6457 C CB . ALA B 1 416 ? 106.312 -19.041 76.333 1.00 26.44 ? 418 ALA B CB 1 ATOM 6458 N N . SER B 1 417 ? 105.024 -21.910 74.914 1.00 29.68 ? 419 SER B N 1 ATOM 6459 C CA . SER B 1 417 ? 104.559 -22.527 73.676 1.00 30.54 ? 419 SER B CA 1 ATOM 6460 C C . SER B 1 417 ? 103.446 -21.711 73.032 1.00 31.76 ? 419 SER B C 1 ATOM 6461 O O . SER B 1 417 ? 102.709 -20.996 73.715 1.00 32.00 ? 419 SER B O 1 ATOM 6462 C CB . SER B 1 417 ? 104.061 -23.949 73.937 1.00 30.28 ? 419 SER B CB 1 ATOM 6463 O OG . SER B 1 417 ? 105.053 -24.729 74.578 1.00 35.93 ? 419 SER B OG 1 ATOM 6464 N N . LEU B 1 418 ? 103.329 -21.822 71.713 1.00 29.78 ? 420 LEU B N 1 ATOM 6465 C CA . LEU B 1 418 ? 102.132 -21.372 71.011 1.00 28.24 ? 420 LEU B CA 1 ATOM 6466 C C . LEU B 1 418 ? 101.526 -22.505 70.196 1.00 27.69 ? 420 LEU B C 1 ATOM 6467 O O . LEU B 1 418 ? 102.245 -23.314 69.606 1.00 24.69 ? 420 LEU B O 1 ATOM 6468 C CB . LEU B 1 418 ? 102.450 -20.185 70.102 1.00 28.65 ? 420 LEU B CB 1 ATOM 6469 C CG . LEU B 1 418 ? 102.714 -18.845 70.790 1.00 29.31 ? 420 LEU B CG 1 ATOM 6470 C CD1 . LEU B 1 418 ? 103.171 -17.807 69.778 1.00 28.10 ? 420 LEU B CD1 1 ATOM 6471 C CD2 . LEU B 1 418 ? 101.477 -18.367 71.534 1.00 28.30 ? 420 LEU B CD2 1 ATOM 6472 N N . SER B 1 419 ? 100.199 -22.577 70.196 1.00 25.68 ? 421 SER B N 1 ATOM 6473 C CA . SER B 1 419 ? 99.479 -23.461 69.294 1.00 24.31 ? 421 SER B CA 1 ATOM 6474 C C . SER B 1 419 ? 98.963 -22.663 68.104 1.00 24.86 ? 421 SER B C 1 ATOM 6475 O O . SER B 1 419 ? 98.136 -21.763 68.257 1.00 23.42 ? 421 SER B O 1 ATOM 6476 C CB . SER B 1 419 ? 98.317 -24.135 70.021 1.00 27.32 ? 421 SER B CB 1 ATOM 6477 O OG . SER B 1 419 ? 97.630 -25.025 69.160 1.00 33.80 ? 421 SER B OG 1 ATOM 6478 N N . ILE B 1 420 ? 99.490 -22.968 66.923 1.00 22.23 ? 422 ILE B N 1 ATOM 6479 C CA . ILE B 1 420 ? 99.348 -22.084 65.775 1.00 20.14 ? 422 ILE B CA 1 ATOM 6480 C C . ILE B 1 420 ? 98.629 -22.800 64.641 1.00 18.77 ? 422 ILE B C 1 ATOM 6481 O O . ILE B 1 420 ? 99.109 -23.816 64.141 1.00 16.65 ? 422 ILE B O 1 ATOM 6482 C CB . ILE B 1 420 ? 100.718 -21.584 65.278 1.00 19.90 ? 422 ILE B CB 1 ATOM 6483 C CG1 . ILE B 1 420 ? 101.489 -20.913 66.418 1.00 19.88 ? 422 ILE B CG1 1 ATOM 6484 C CG2 . ILE B 1 420 ? 100.549 -20.611 64.122 1.00 18.30 ? 422 ILE B CG2 1 ATOM 6485 C CD1 . ILE B 1 420 ? 102.913 -20.548 66.060 1.00 19.21 ? 422 ILE B CD1 1 ATOM 6486 N N . PRO B 1 421 ? 97.450 -22.290 64.256 1.00 18.19 ? 423 PRO B N 1 ATOM 6487 C CA . PRO B 1 421 ? 96.770 -22.823 63.083 1.00 19.25 ? 423 PRO B CA 1 ATOM 6488 C C . PRO B 1 421 ? 97.677 -22.702 61.864 1.00 18.39 ? 423 PRO B C 1 ATOM 6489 O O . PRO B 1 421 ? 98.563 -21.849 61.842 1.00 18.36 ? 423 PRO B O 1 ATOM 6490 C CB . PRO B 1 421 ? 95.553 -21.897 62.925 1.00 19.53 ? 423 PRO B CB 1 ATOM 6491 C CG . PRO B 1 421 ? 95.408 -21.200 64.240 1.00 20.30 ? 423 PRO B CG 1 ATOM 6492 C CD . PRO B 1 421 ? 96.803 -21.073 64.769 1.00 19.32 ? 423 PRO B CD 1 ATOM 6493 N N . GLN B 1 422 ? 97.468 -23.559 60.870 1.00 20.47 ? 424 GLN B N 1 ATOM 6494 C CA . GLN B 1 422 ? 98.193 -23.454 59.607 1.00 19.70 ? 424 GLN B CA 1 ATOM 6495 C C . GLN B 1 422 ? 97.861 -22.152 58.891 1.00 19.24 ? 424 GLN B C 1 ATOM 6496 O O . GLN B 1 422 ? 96.692 -21.824 58.702 1.00 18.53 ? 424 GLN B O 1 ATOM 6497 C CB . GLN B 1 422 ? 97.849 -24.630 58.695 1.00 21.31 ? 424 GLN B CB 1 ATOM 6498 C CG . GLN B 1 422 ? 98.453 -25.954 59.123 1.00 21.64 ? 424 GLN B CG 1 ATOM 6499 C CD . GLN B 1 422 ? 98.302 -27.027 58.065 1.00 21.95 ? 424 GLN B CD 1 ATOM 6500 O OE1 . GLN B 1 422 ? 98.332 -26.743 56.867 1.00 24.54 ? 424 GLN B OE1 1 ATOM 6501 N NE2 . GLN B 1 422 ? 98.139 -28.267 58.501 1.00 21.59 ? 424 GLN B NE2 1 ATOM 6502 N N . PHE B 1 423 ? 98.891 -21.434 58.455 1.00 19.76 ? 425 PHE B N 1 ATOM 6503 C CA . PHE B 1 423 ? 98.698 -20.285 57.576 1.00 19.58 ? 425 PHE B CA 1 ATOM 6504 C C . PHE B 1 423 ? 99.070 -20.635 56.142 1.00 17.47 ? 425 PHE B C 1 ATOM 6505 O O . PHE B 1 423 ? 98.783 -19.881 55.211 1.00 16.19 ? 425 PHE B O 1 ATOM 6506 C CB . PHE B 1 423 ? 99.529 -19.098 58.058 1.00 22.00 ? 425 PHE B CB 1 ATOM 6507 C CG . PHE B 1 423 ? 99.277 -18.730 59.490 1.00 25.50 ? 425 PHE B CG 1 ATOM 6508 C CD1 . PHE B 1 423 ? 97.987 -18.524 59.946 1.00 27.29 ? 425 PHE B CD1 1 ATOM 6509 C CD2 . PHE B 1 423 ? 100.328 -18.604 60.382 1.00 28.62 ? 425 PHE B CD2 1 ATOM 6510 C CE1 . PHE B 1 423 ? 97.748 -18.190 61.266 1.00 30.25 ? 425 PHE B CE1 1 ATOM 6511 C CE2 . PHE B 1 423 ? 100.098 -18.257 61.700 1.00 30.10 ? 425 PHE B CE2 1 ATOM 6512 C CZ . PHE B 1 423 ? 98.806 -18.058 62.144 1.00 30.03 ? 425 PHE B CZ 1 ATOM 6513 N N . VAL B 1 424 ? 99.751 -21.765 55.983 1.00 16.21 ? 426 VAL B N 1 ATOM 6514 C CA . VAL B 1 424 ? 100.120 -22.273 54.670 1.00 15.92 ? 426 VAL B CA 1 ATOM 6515 C C . VAL B 1 424 ? 99.407 -23.597 54.421 1.00 16.99 ? 426 VAL B C 1 ATOM 6516 O O . VAL B 1 424 ? 99.490 -24.522 55.233 1.00 17.92 ? 426 VAL B O 1 ATOM 6517 C CB . VAL B 1 424 ? 101.642 -22.486 54.561 1.00 16.00 ? 426 VAL B CB 1 ATOM 6518 C CG1 . VAL B 1 424 ? 101.999 -23.136 53.232 1.00 17.03 ? 426 VAL B CG1 1 ATOM 6519 C CG2 . VAL B 1 424 ? 102.374 -21.164 54.726 1.00 16.23 ? 426 VAL B CG2 1 ATOM 6520 N N . VAL B 1 425 ? 98.655 -23.664 53.327 1.00 15.34 ? 427 VAL B N 1 ATOM 6521 C CA . VAL B 1 425 ? 97.833 -24.830 53.049 1.00 15.30 ? 427 VAL B CA 1 ATOM 6522 C C . VAL B 1 425 ? 98.232 -25.455 51.720 1.00 15.09 ? 427 VAL B C 1 ATOM 6523 O O . VAL B 1 425 ? 98.102 -24.833 50.665 1.00 13.95 ? 427 VAL B O 1 ATOM 6524 C CB . VAL B 1 425 ? 96.334 -24.477 53.032 1.00 15.30 ? 427 VAL B CB 1 ATOM 6525 C CG1 . VAL B 1 425 ? 95.506 -25.699 52.664 1.00 15.55 ? 427 VAL B CG1 1 ATOM 6526 C CG2 . VAL B 1 425 ? 95.907 -23.924 54.388 1.00 16.54 ? 427 VAL B CG2 1 ATOM 6527 N N . SER B 1 426 ? 98.741 -26.681 51.781 1.00 14.93 ? 428 SER B N 1 ATOM 6528 C CA . SER B 1 426 ? 99.204 -27.364 50.583 1.00 15.23 ? 428 SER B CA 1 ATOM 6529 C C . SER B 1 426 ? 98.041 -27.771 49.692 1.00 15.06 ? 428 SER B C 1 ATOM 6530 O O . SER B 1 426 ? 97.123 -28.464 50.129 1.00 15.31 ? 428 SER B O 1 ATOM 6531 C CB . SER B 1 426 ? 100.032 -28.595 50.946 1.00 16.70 ? 428 SER B CB 1 ATOM 6532 O OG . SER B 1 426 ? 100.270 -29.386 49.792 1.00 17.82 ? 428 SER B OG 1 ATOM 6533 N N . HIS B 1 427 ? 98.092 -27.356 48.432 1.00 14.82 ? 429 HIS B N 1 ATOM 6534 C CA . HIS B 1 427 ? 97.184 -27.890 47.429 1.00 14.60 ? 429 HIS B CA 1 ATOM 6535 C C . HIS B 1 427 ? 97.904 -28.874 46.524 1.00 13.53 ? 429 HIS B C 1 ATOM 6536 O O . HIS B 1 427 ? 97.427 -29.209 45.439 1.00 11.85 ? 429 HIS B O 1 ATOM 6537 C CB . HIS B 1 427 ? 96.554 -26.758 46.621 1.00 16.69 ? 429 HIS B CB 1 ATOM 6538 C CG . HIS B 1 427 ? 95.667 -25.868 47.433 1.00 18.39 ? 429 HIS B CG 1 ATOM 6539 N ND1 . HIS B 1 427 ? 94.638 -26.356 48.209 1.00 21.97 ? 429 HIS B ND1 1 ATOM 6540 C CD2 . HIS B 1 427 ? 95.684 -24.529 47.628 1.00 20.37 ? 429 HIS B CD2 1 ATOM 6541 C CE1 . HIS B 1 427 ? 94.042 -25.351 48.827 1.00 23.86 ? 429 HIS B CE1 1 ATOM 6542 N NE2 . HIS B 1 427 ? 94.657 -24.231 48.491 1.00 21.94 ? 429 HIS B NE2 1 ATOM 6543 N N . GLY B 1 428 ? 99.051 -29.350 46.992 1.00 13.12 ? 430 GLY B N 1 ATOM 6544 C CA . GLY B 1 428 ? 99.742 -30.450 46.337 1.00 12.86 ? 430 GLY B CA 1 ATOM 6545 C C . GLY B 1 428 ? 100.677 -29.989 45.238 1.00 12.15 ? 430 GLY B C 1 ATOM 6546 O O . GLY B 1 428 ? 100.962 -28.797 45.100 1.00 11.88 ? 430 GLY B O 1 ATOM 6547 N N . GLY B 1 429 ? 101.133 -30.944 44.439 1.00 11.72 ? 431 GLY B N 1 ATOM 6548 C CA . GLY B 1 429 ? 102.153 -30.691 43.434 1.00 10.52 ? 431 GLY B CA 1 ATOM 6549 C C . GLY B 1 429 ? 102.689 -32.002 42.900 1.00 10.37 ? 431 GLY B C 1 ATOM 6550 O O . GLY B 1 429 ? 102.067 -33.052 43.064 1.00 9.58 ? 431 GLY B O 1 ATOM 6551 N N . GLU B 1 430 ? 103.861 -31.944 42.281 1.00 10.07 ? 432 GLU B N 1 ATOM 6552 C CA . GLU B 1 430 ? 104.469 -33.123 41.687 1.00 9.78 ? 432 GLU B CA 1 ATOM 6553 C C . GLU B 1 430 ? 105.988 -33.011 41.732 1.00 9.83 ? 432 GLU B C 1 ATOM 6554 O O . GLU B 1 430 ? 106.540 -31.920 41.913 1.00 9.26 ? 432 GLU B O 1 ATOM 6555 C CB . GLU B 1 430 ? 103.975 -33.315 40.248 1.00 10.31 ? 432 GLU B CB 1 ATOM 6556 C CG . GLU B 1 430 ? 104.425 -34.609 39.580 1.00 10.49 ? 432 GLU B CG 1 ATOM 6557 C CD . GLU B 1 430 ? 104.091 -35.845 40.399 1.00 11.80 ? 432 GLU B CD 1 ATOM 6558 O OE1 . GLU B 1 430 ? 104.838 -36.145 41.355 1.00 10.76 ? 432 GLU B OE1 1 ATOM 6559 O OE2 . GLU B 1 430 ? 103.104 -36.540 40.062 1.00 11.94 ? 432 GLU B OE2 1 ATOM 6560 N N . TYR B 1 431 ? 106.645 -34.162 41.658 1.00 9.67 ? 433 TYR B N 1 ATOM 6561 C CA . TYR B 1 431 ? 108.085 -34.237 41.476 1.00 9.42 ? 433 TYR B CA 1 ATOM 6562 C C . TYR B 1 431 ? 108.406 -34.411 39.992 1.00 9.31 ? 433 TYR B C 1 ATOM 6563 O O . TYR B 1 431 ? 107.872 -35.308 39.334 1.00 9.26 ? 433 TYR B O 1 ATOM 6564 C CB . TYR B 1 431 ? 108.648 -35.422 42.265 1.00 9.51 ? 433 TYR B CB 1 ATOM 6565 C CG . TYR B 1 431 ? 108.449 -35.336 43.766 1.00 9.62 ? 433 TYR B CG 1 ATOM 6566 C CD1 . TYR B 1 431 ? 108.597 -34.132 44.437 1.00 10.07 ? 433 TYR B CD1 1 ATOM 6567 C CD2 . TYR B 1 431 ? 108.191 -36.477 44.519 1.00 9.91 ? 433 TYR B CD2 1 ATOM 6568 C CE1 . TYR B 1 431 ? 108.461 -34.056 45.814 1.00 10.22 ? 433 TYR B CE1 1 ATOM 6569 C CE2 . TYR B 1 431 ? 108.050 -36.411 45.898 1.00 10.68 ? 433 TYR B CE2 1 ATOM 6570 C CZ . TYR B 1 431 ? 108.186 -35.196 46.539 1.00 10.57 ? 433 TYR B CZ 1 ATOM 6571 O OH . TYR B 1 431 ? 108.051 -35.113 47.912 1.00 11.30 ? 433 TYR B OH 1 ATOM 6572 N N . PHE B 1 432 ? 109.265 -33.543 39.464 1.00 8.81 ? 434 PHE B N 1 ATOM 6573 C CA . PHE B 1 432 ? 109.668 -33.627 38.059 1.00 9.00 ? 434 PHE B CA 1 ATOM 6574 C C . PHE B 1 432 ? 111.178 -33.758 37.948 1.00 8.67 ? 434 PHE B C 1 ATOM 6575 O O . PHE B 1 432 ? 111.906 -33.463 38.895 1.00 8.35 ? 434 PHE B O 1 ATOM 6576 C CB . PHE B 1 432 ? 109.231 -32.381 37.278 1.00 8.46 ? 434 PHE B CB 1 ATOM 6577 C CG . PHE B 1 432 ? 107.754 -32.121 37.318 1.00 9.44 ? 434 PHE B CG 1 ATOM 6578 C CD1 . PHE B 1 432 ? 107.194 -31.386 38.353 1.00 9.50 ? 434 PHE B CD1 1 ATOM 6579 C CD2 . PHE B 1 432 ? 106.925 -32.602 36.316 1.00 9.20 ? 434 PHE B CD2 1 ATOM 6580 C CE1 . PHE B 1 432 ? 105.834 -31.141 38.393 1.00 9.68 ? 434 PHE B CE1 1 ATOM 6581 C CE2 . PHE B 1 432 ? 105.563 -32.357 36.348 1.00 9.93 ? 434 PHE B CE2 1 ATOM 6582 C CZ . PHE B 1 432 ? 105.018 -31.624 37.387 1.00 10.08 ? 434 PHE B CZ 1 ATOM 6583 N N . PHE B 1 433 ? 111.644 -34.120 36.756 1.00 8.46 ? 435 PHE B N 1 ATOM 6584 C CA . PHE B 1 433 ? 113.064 -34.039 36.436 1.00 8.79 ? 435 PHE B CA 1 ATOM 6585 C C . PHE B 1 433 ? 113.268 -33.049 35.298 1.00 8.86 ? 435 PHE B C 1 ATOM 6586 O O . PHE B 1 433 ? 112.718 -33.228 34.211 1.00 9.10 ? 435 PHE B O 1 ATOM 6587 C CB . PHE B 1 433 ? 113.605 -35.415 36.036 1.00 8.27 ? 435 PHE B CB 1 ATOM 6588 C CG . PHE B 1 433 ? 115.072 -35.415 35.691 1.00 8.76 ? 435 PHE B CG 1 ATOM 6589 C CD1 . PHE B 1 433 ? 116.023 -35.165 36.667 1.00 8.63 ? 435 PHE B CD1 1 ATOM 6590 C CD2 . PHE B 1 433 ? 115.496 -35.649 34.391 1.00 8.97 ? 435 PHE B CD2 1 ATOM 6591 C CE1 . PHE B 1 433 ? 117.372 -35.158 36.358 1.00 8.67 ? 435 PHE B CE1 1 ATOM 6592 C CE2 . PHE B 1 433 ? 116.842 -35.640 34.072 1.00 8.81 ? 435 PHE B CE2 1 ATOM 6593 C CZ . PHE B 1 433 ? 117.782 -35.397 35.058 1.00 8.87 ? 435 PHE B CZ 1 ATOM 6594 N N . SER B 1 434 ? 114.016 -31.982 35.564 1.00 9.34 ? 436 SER B N 1 ATOM 6595 C CA . SER B 1 434 ? 114.416 -31.051 34.514 1.00 9.48 ? 436 SER B CA 1 ATOM 6596 C C . SER B 1 434 ? 115.708 -31.537 33.871 1.00 9.50 ? 436 SER B C 1 ATOM 6597 O O . SER B 1 434 ? 116.774 -31.448 34.480 1.00 9.32 ? 436 SER B O 1 ATOM 6598 C CB . SER B 1 434 ? 114.630 -29.640 35.077 1.00 9.80 ? 436 SER B CB 1 ATOM 6599 O OG . SER B 1 434 ? 113.506 -29.202 35.824 1.00 12.50 ? 436 SER B OG 1 ATOM 6600 N N . PRO B 1 435 ? 115.620 -32.035 32.629 1.00 9.32 ? 437 PRO B N 1 ATOM 6601 C CA . PRO B 1 435 ? 116.778 -32.647 31.992 1.00 9.26 ? 437 PRO B CA 1 ATOM 6602 C C . PRO B 1 435 ? 117.791 -31.599 31.550 1.00 9.41 ? 437 PRO B C 1 ATOM 6603 O O . PRO B 1 435 ? 117.449 -30.425 31.422 1.00 9.16 ? 437 PRO B O 1 ATOM 6604 C CB . PRO B 1 435 ? 116.179 -33.346 30.768 1.00 9.54 ? 437 PRO B CB 1 ATOM 6605 C CG . PRO B 1 435 ? 114.942 -32.578 30.462 1.00 10.03 ? 437 PRO B CG 1 ATOM 6606 C CD . PRO B 1 435 ? 114.410 -32.118 31.793 1.00 9.74 ? 437 PRO B CD 1 ATOM 6607 N N . PRO B 1 436 ? 119.042 -32.019 31.333 1.00 9.37 ? 438 PRO B N 1 ATOM 6608 C CA . PRO B 1 436 ? 119.963 -31.164 30.597 1.00 10.02 ? 438 PRO B CA 1 ATOM 6609 C C . PRO B 1 436 ? 119.391 -30.860 29.217 1.00 10.00 ? 438 PRO B C 1 ATOM 6610 O O . PRO B 1 436 ? 118.604 -31.644 28.684 1.00 10.70 ? 438 PRO B O 1 ATOM 6611 C CB . PRO B 1 436 ? 121.227 -32.020 30.480 1.00 9.84 ? 438 PRO B CB 1 ATOM 6612 C CG . PRO B 1 436 ? 120.754 -33.426 30.620 1.00 10.14 ? 438 PRO B CG 1 ATOM 6613 C CD . PRO B 1 436 ? 119.571 -33.377 31.542 1.00 9.69 ? 438 PRO B CD 1 ATOM 6614 N N . ILE B 1 437 ? 119.737 -29.704 28.668 1.00 10.26 ? 439 ILE B N 1 ATOM 6615 C CA . ILE B 1 437 ? 119.126 -29.254 27.422 1.00 10.76 ? 439 ILE B CA 1 ATOM 6616 C C . ILE B 1 437 ? 119.406 -30.224 26.276 1.00 11.09 ? 439 ILE B C 1 ATOM 6617 O O . ILE B 1 437 ? 118.532 -30.485 25.452 1.00 10.67 ? 439 ILE B O 1 ATOM 6618 C CB . ILE B 1 437 ? 119.557 -27.817 27.068 1.00 11.16 ? 439 ILE B CB 1 ATOM 6619 C CG1 . ILE B 1 437 ? 119.102 -26.853 28.169 1.00 10.64 ? 439 ILE B CG1 1 ATOM 6620 C CG2 . ILE B 1 437 ? 118.986 -27.395 25.722 1.00 11.68 ? 439 ILE B CG2 1 ATOM 6621 C CD1 . ILE B 1 437 ? 119.594 -25.432 27.994 1.00 11.07 ? 439 ILE B CD1 1 ATOM 6622 N N . SER B 1 438 ? 120.583 -30.848 26.297 1.00 11.43 ? 440 SER B N 1 ATOM 6623 C CA . SER B 1 438 ? 120.952 -31.827 25.274 1.00 11.57 ? 440 SER B CA 1 ATOM 6624 C C . SER B 1 438 ? 120.013 -33.037 25.236 1.00 11.40 ? 440 SER B C 1 ATOM 6625 O O . SER B 1 438 ? 119.843 -33.663 24.192 1.00 12.19 ? 440 SER B O 1 ATOM 6626 C CB . SER B 1 438 ? 122.399 -32.290 25.467 1.00 12.17 ? 440 SER B CB 1 ATOM 6627 O OG . SER B 1 438 ? 122.580 -32.883 26.743 1.00 12.78 ? 440 SER B OG 1 ATOM 6628 N N . ALA B 1 439 ? 119.391 -33.357 26.367 1.00 11.12 ? 441 ALA B N 1 ATOM 6629 C CA . ALA B 1 439 ? 118.512 -34.528 26.444 1.00 11.08 ? 441 ALA B CA 1 ATOM 6630 C C . ALA B 1 439 ? 117.140 -34.266 25.824 1.00 11.13 ? 441 ALA B C 1 ATOM 6631 O O . ALA B 1 439 ? 116.413 -35.199 25.487 1.00 10.02 ? 441 ALA B O 1 ATOM 6632 C CB . ALA B 1 439 ? 118.361 -34.988 27.884 1.00 11.11 ? 441 ALA B CB 1 ATOM 6633 N N . ILE B 1 440 ? 116.784 -32.994 25.684 1.00 10.75 ? 442 ILE B N 1 ATOM 6634 C CA . ILE B 1 440 ? 115.450 -32.629 25.222 1.00 11.24 ? 442 ILE B CA 1 ATOM 6635 C C . ILE B 1 440 ? 115.271 -32.934 23.735 1.00 11.51 ? 442 ILE B C 1 ATOM 6636 O O . ILE B 1 440 ? 114.328 -33.627 23.343 1.00 12.20 ? 442 ILE B O 1 ATOM 6637 C CB . ILE B 1 440 ? 115.142 -31.146 25.511 1.00 11.49 ? 442 ILE B CB 1 ATOM 6638 C CG1 . ILE B 1 440 ? 115.196 -30.886 27.020 1.00 11.48 ? 442 ILE B CG1 1 ATOM 6639 C CG2 . ILE B 1 440 ? 113.773 -30.767 24.961 1.00 10.97 ? 442 ILE B CG2 1 ATOM 6640 C CD1 . ILE B 1 440 ? 115.096 -29.422 27.403 1.00 12.19 ? 442 ILE B CD1 1 ATOM 6641 N N . GLY B 1 441 ? 116.211 -32.470 22.919 1.00 11.12 ? 443 GLY B N 1 ATOM 6642 C CA . GLY B 1 441 ? 116.260 -32.856 21.513 1.00 11.46 ? 443 GLY B CA 1 ATOM 6643 C C . GLY B 1 441 ? 117.074 -34.119 21.303 1.00 11.74 ? 443 GLY B C 1 ATOM 6644 O O . GLY B 1 441 ? 117.250 -34.574 20.172 1.00 11.99 ? 443 GLY B O 1 ATOM 6645 N N . GLY B 1 442 ? 117.573 -34.681 22.400 1.00 10.91 ? 444 GLY B N 1 ATOM 6646 C CA . GLY B 1 442 ? 118.339 -35.924 22.358 1.00 10.47 ? 444 GLY B CA 1 ATOM 6647 C C . GLY B 1 442 ? 117.502 -37.110 22.798 1.00 10.86 ? 444 GLY B C 1 ATOM 6648 O O . GLY B 1 442 ? 116.470 -37.416 22.188 1.00 10.78 ? 444 GLY B O 1 ATOM 6649 N N . ARG B 1 443 ? 117.919 -37.752 23.887 1.00 10.54 ? 445 ARG B N 1 ATOM 6650 C CA . ARG B 1 443 ? 117.307 -39.008 24.319 1.00 10.36 ? 445 ARG B CA 1 ATOM 6651 C C . ARG B 1 443 ? 115.784 -38.918 24.389 1.00 10.19 ? 445 ARG B C 1 ATOM 6652 O O . ARG B 1 443 ? 115.083 -39.846 23.987 1.00 9.98 ? 445 ARG B O 1 ATOM 6653 C CB . ARG B 1 443 ? 117.862 -39.451 25.678 1.00 10.01 ? 445 ARG B CB 1 ATOM 6654 C CG . ARG B 1 443 ? 117.160 -40.666 26.268 1.00 10.12 ? 445 ARG B CG 1 ATOM 6655 C CD . ARG B 1 443 ? 117.338 -41.886 25.376 1.00 10.16 ? 445 ARG B CD 1 ATOM 6656 N NE . ARG B 1 443 ? 116.584 -43.053 25.829 1.00 10.46 ? 445 ARG B NE 1 ATOM 6657 C CZ . ARG B 1 443 ? 115.373 -43.382 25.384 1.00 11.00 ? 445 ARG B CZ 1 ATOM 6658 N NH1 . ARG B 1 443 ? 114.742 -42.587 24.531 1.00 10.38 ? 445 ARG B NH1 1 ATOM 6659 N NH2 . ARG B 1 443 ? 114.779 -44.489 25.816 1.00 10.77 ? 445 ARG B NH2 1 ATOM 6660 N N . LEU B 1 444 ? 115.267 -37.824 24.932 1.00 10.24 ? 446 LEU B N 1 ATOM 6661 C CA . LEU B 1 444 ? 113.831 -37.742 25.185 1.00 10.45 ? 446 LEU B CA 1 ATOM 6662 C C . LEU B 1 444 ? 113.035 -37.677 23.878 1.00 11.16 ? 446 LEU B C 1 ATOM 6663 O O . LEU B 1 444 ? 111.857 -38.031 23.840 1.00 11.40 ? 446 LEU B O 1 ATOM 6664 C CB . LEU B 1 444 ? 113.496 -36.554 26.086 1.00 10.22 ? 446 LEU B CB 1 ATOM 6665 C CG . LEU B 1 444 ? 114.139 -36.547 27.478 1.00 11.01 ? 446 LEU B CG 1 ATOM 6666 C CD1 . LEU B 1 444 ? 113.580 -35.407 28.317 1.00 11.27 ? 446 LEU B CD1 1 ATOM 6667 C CD2 . LEU B 1 444 ? 113.950 -37.879 28.189 1.00 10.38 ? 446 LEU B CD2 1 ATOM 6668 N N . SER B 1 445 ? 113.694 -37.257 22.804 1.00 12.37 ? 447 SER B N 1 ATOM 6669 C CA . SER B 1 445 ? 113.050 -37.182 21.496 1.00 13.32 ? 447 SER B CA 1 ATOM 6670 C C . SER B 1 445 ? 113.296 -38.428 20.643 1.00 15.12 ? 447 SER B C 1 ATOM 6671 O O . SER B 1 445 ? 112.731 -38.562 19.557 1.00 15.11 ? 447 SER B O 1 ATOM 6672 C CB . SER B 1 445 ? 113.516 -35.937 20.742 1.00 13.36 ? 447 SER B CB 1 ATOM 6673 O OG . SER B 1 445 ? 113.009 -34.756 21.343 1.00 13.94 ? 447 SER B OG 1 ATOM 6674 N N . ALA B 1 446 ? 114.137 -39.335 21.134 1.00 16.07 ? 448 ALA B N 1 ATOM 6675 C CA . ALA B 1 446 ? 114.569 -40.480 20.336 1.00 18.26 ? 448 ALA B CA 1 ATOM 6676 C C . ALA B 1 446 ? 113.566 -41.626 20.403 1.00 20.16 ? 448 ALA B C 1 ATOM 6677 O O . ALA B 1 446 ? 113.490 -42.448 19.492 1.00 22.89 ? 448 ALA B O 1 ATOM 6678 C CB . ALA B 1 446 ? 115.947 -40.952 20.776 1.00 18.58 ? 448 ALA B CB 1 ATOM 6679 O OXT . ALA B 1 446 ? 112.804 -41.758 21.362 1.00 20.54 ? 448 ALA B OXT 1 HETATM 6680 AS AS . CAC C 2 . ? 80.911 9.552 -7.700 1.00 27.72 ? 1449 CAC A AS 1 HETATM 6681 O O1 . CAC C 2 . ? 81.558 8.059 -8.323 1.00 22.52 ? 1449 CAC A O1 1 HETATM 6682 O O2 . CAC C 2 . ? 79.478 9.983 -8.584 1.00 25.70 ? 1449 CAC A O2 1 HETATM 6683 C C1 . CAC C 2 . ? 80.484 9.335 -5.796 1.00 24.00 ? 1449 CAC A C1 1 HETATM 6684 C C2 . CAC C 2 . ? 82.260 10.968 -7.890 1.00 24.46 ? 1449 CAC A C2 1 HETATM 6685 C C1 . GOL D 3 . ? 99.129 -9.397 39.541 1.00 28.44 ? 1450 GOL A C1 1 HETATM 6686 O O1 . GOL D 3 . ? 100.314 -10.052 40.008 1.00 30.38 ? 1450 GOL A O1 1 HETATM 6687 C C2 . GOL D 3 . ? 98.009 -9.621 40.549 1.00 27.40 ? 1450 GOL A C2 1 HETATM 6688 O O2 . GOL D 3 . ? 98.370 -9.032 41.805 1.00 26.81 ? 1450 GOL A O2 1 HETATM 6689 C C3 . GOL D 3 . ? 96.734 -8.966 40.035 1.00 26.91 ? 1450 GOL A C3 1 HETATM 6690 O O3 . GOL D 3 . ? 95.661 -9.264 40.935 1.00 24.84 ? 1450 GOL A O3 1 HETATM 6691 C C1 . GOL E 3 . ? 95.513 -9.517 8.435 1.00 27.32 ? 1451 GOL A C1 1 HETATM 6692 O O1 . GOL E 3 . ? 96.407 -8.769 7.600 1.00 27.46 ? 1451 GOL A O1 1 HETATM 6693 C C2 . GOL E 3 . ? 96.255 -10.661 9.117 1.00 30.23 ? 1451 GOL A C2 1 HETATM 6694 O O2 . GOL E 3 . ? 95.599 -11.902 8.812 1.00 31.34 ? 1451 GOL A O2 1 HETATM 6695 C C3 . GOL E 3 . ? 96.254 -10.441 10.627 1.00 29.90 ? 1451 GOL A C3 1 HETATM 6696 O O3 . GOL E 3 . ? 97.160 -9.381 10.965 1.00 30.07 ? 1451 GOL A O3 1 HETATM 6697 C C1 . GOL F 3 . ? 95.266 12.930 2.409 1.00 34.91 ? 1452 GOL A C1 1 HETATM 6698 O O1 . GOL F 3 . ? 94.610 13.777 1.459 1.00 39.24 ? 1452 GOL A O1 1 HETATM 6699 C C2 . GOL F 3 . ? 94.380 12.765 3.635 1.00 32.30 ? 1452 GOL A C2 1 HETATM 6700 O O2 . GOL F 3 . ? 93.427 11.720 3.402 1.00 34.59 ? 1452 GOL A O2 1 HETATM 6701 C C3 . GOL F 3 . ? 95.235 12.441 4.857 1.00 32.52 ? 1452 GOL A C3 1 HETATM 6702 O O3 . GOL F 3 . ? 96.160 11.384 4.565 1.00 27.97 ? 1452 GOL A O3 1 HETATM 6703 C C1 . GOL G 3 . ? 58.635 10.483 23.483 1.00 41.65 ? 1453 GOL A C1 1 HETATM 6704 O O1 . GOL G 3 . ? 58.762 9.219 22.818 1.00 45.47 ? 1453 GOL A O1 1 HETATM 6705 C C2 . GOL G 3 . ? 60.017 11.094 23.675 1.00 37.16 ? 1453 GOL A C2 1 HETATM 6706 O O2 . GOL G 3 . ? 60.917 10.098 24.175 1.00 39.37 ? 1453 GOL A O2 1 HETATM 6707 C C3 . GOL G 3 . ? 60.529 11.616 22.340 1.00 35.31 ? 1453 GOL A C3 1 HETATM 6708 O O3 . GOL G 3 . ? 60.731 13.031 22.430 1.00 42.17 ? 1453 GOL A O3 1 HETATM 6709 C C1 . NAG H 4 . ? 82.335 14.033 0.329 1.00 19.22 ? 1454 NAG A C1 1 HETATM 6710 C C2 . NAG H 4 . ? 83.427 15.094 0.245 1.00 21.73 ? 1454 NAG A C2 1 HETATM 6711 C C3 . NAG H 4 . ? 82.947 16.274 -0.592 1.00 23.17 ? 1454 NAG A C3 1 HETATM 6712 C C4 . NAG H 4 . ? 82.404 15.800 -1.936 1.00 23.10 ? 1454 NAG A C4 1 HETATM 6713 C C5 . NAG H 4 . ? 81.432 14.636 -1.761 1.00 21.22 ? 1454 NAG A C5 1 HETATM 6714 C C6 . NAG H 4 . ? 81.040 14.056 -3.114 1.00 21.07 ? 1454 NAG A C6 1 HETATM 6715 C C7 . NAG H 4 . ? 85.100 15.516 1.946 1.00 22.76 ? 1454 NAG A C7 1 HETATM 6716 C C8 . NAG H 4 . ? 85.406 16.009 3.329 1.00 22.48 ? 1454 NAG A C8 1 HETATM 6717 N N2 . NAG H 4 . ? 83.826 15.550 1.565 1.00 21.62 ? 1454 NAG A N2 1 HETATM 6718 O O3 . NAG H 4 . ? 84.018 17.169 -0.794 1.00 23.93 ? 1454 NAG A O3 1 HETATM 6719 O O4 . NAG H 4 . ? 81.712 16.866 -2.545 1.00 26.95 ? 1454 NAG A O4 1 HETATM 6720 O O5 . NAG H 4 . ? 82.028 13.621 -0.985 1.00 20.11 ? 1454 NAG A O5 1 HETATM 6721 O O6 . NAG H 4 . ? 80.133 12.994 -2.931 1.00 20.27 ? 1454 NAG A O6 1 HETATM 6722 O O7 . NAG H 4 . ? 86.002 15.099 1.220 1.00 24.15 ? 1454 NAG A O7 1 HETATM 6723 C C1 . NAG I 4 . ? 82.254 17.111 -3.853 1.00 28.51 ? 1457 NAG A C1 1 HETATM 6724 C C2 . NAG I 4 . ? 81.264 17.970 -4.636 1.00 30.58 ? 1457 NAG A C2 1 HETATM 6725 C C3 . NAG I 4 . ? 81.828 18.365 -5.994 1.00 31.98 ? 1457 NAG A C3 1 HETATM 6726 C C4 . NAG I 4 . ? 83.222 18.949 -5.826 1.00 34.40 ? 1457 NAG A C4 1 HETATM 6727 C C5 . NAG I 4 . ? 84.091 17.964 -5.053 1.00 34.71 ? 1457 NAG A C5 1 HETATM 6728 C C6 . NAG I 4 . ? 85.507 18.497 -4.878 1.00 34.70 ? 1457 NAG A C6 1 HETATM 6729 C C7 . NAG I 4 . ? 79.003 17.381 -3.969 1.00 32.28 ? 1457 NAG A C7 1 HETATM 6730 C C8 . NAG I 4 . ? 77.761 16.600 -4.283 1.00 31.68 ? 1457 NAG A C8 1 HETATM 6731 N N2 . NAG I 4 . ? 80.012 17.262 -4.827 1.00 29.79 ? 1457 NAG A N2 1 HETATM 6732 O O3 . NAG I 4 . ? 80.981 19.315 -6.592 1.00 33.38 ? 1457 NAG A O3 1 HETATM 6733 O O4 . NAG I 4 . ? 83.778 19.208 -7.095 1.00 38.52 ? 1457 NAG A O4 1 HETATM 6734 O O5 . NAG I 4 . ? 83.514 17.743 -3.782 1.00 31.60 ? 1457 NAG A O5 1 HETATM 6735 O O6 . NAG I 4 . ? 85.470 19.660 -4.079 1.00 36.39 ? 1457 NAG A O6 1 HETATM 6736 O O7 . NAG I 4 . ? 79.062 18.077 -2.956 1.00 32.93 ? 1457 NAG A O7 1 HETATM 6737 C C1 . NAG J 4 . ? 97.680 -23.733 2.800 1.00 17.99 ? 1455 NAG A C1 1 HETATM 6738 C C2 . NAG J 4 . ? 98.470 -24.970 2.379 1.00 18.88 ? 1455 NAG A C2 1 HETATM 6739 C C3 . NAG J 4 . ? 99.417 -24.616 1.241 1.00 19.96 ? 1455 NAG A C3 1 HETATM 6740 C C4 . NAG J 4 . ? 98.644 -23.939 0.115 1.00 20.22 ? 1455 NAG A C4 1 HETATM 6741 C C5 . NAG J 4 . ? 97.858 -22.756 0.666 1.00 20.15 ? 1455 NAG A C5 1 HETATM 6742 C C6 . NAG J 4 . ? 97.045 -22.076 -0.431 1.00 19.12 ? 1455 NAG A C6 1 HETATM 6743 C C7 . NAG J 4 . ? 99.100 -26.799 3.849 1.00 20.62 ? 1455 NAG A C7 1 HETATM 6744 C C8 . NAG J 4 . ? 99.937 -27.272 5.001 1.00 19.86 ? 1455 NAG A C8 1 HETATM 6745 N N2 . NAG J 4 . ? 99.229 -25.523 3.487 1.00 19.11 ? 1455 NAG A N2 1 HETATM 6746 O O3 . NAG J 4 . ? 100.052 -25.783 0.769 1.00 21.02 ? 1455 NAG A O3 1 HETATM 6747 O O4 . NAG J 4 . ? 99.542 -23.476 -0.868 1.00 21.64 ? 1455 NAG A O4 1 HETATM 6748 O O5 . NAG J 4 . ? 96.992 -23.199 1.686 1.00 18.20 ? 1455 NAG A O5 1 HETATM 6749 O O6 . NAG J 4 . ? 95.869 -22.812 -0.674 1.00 20.15 ? 1455 NAG A O6 1 HETATM 6750 O O7 . NAG J 4 . ? 98.319 -27.573 3.302 1.00 20.81 ? 1455 NAG A O7 1 HETATM 6751 C C1 . NAG K 4 . ? 78.755 -15.376 -15.217 1.00 19.36 ? 1456 NAG A C1 1 HETATM 6752 C C2 . NAG K 4 . ? 79.054 -16.169 -16.486 1.00 21.01 ? 1456 NAG A C2 1 HETATM 6753 C C3 . NAG K 4 . ? 77.826 -16.946 -16.940 1.00 20.89 ? 1456 NAG A C3 1 HETATM 6754 C C4 . NAG K 4 . ? 77.330 -17.797 -15.778 1.00 20.56 ? 1456 NAG A C4 1 HETATM 6755 C C5 . NAG K 4 . ? 77.128 -16.923 -14.542 1.00 19.93 ? 1456 NAG A C5 1 HETATM 6756 C C6 . NAG K 4 . ? 76.634 -17.755 -13.363 1.00 19.12 ? 1456 NAG A C6 1 HETATM 6757 C C7 . NAG K 4 . ? 80.839 -15.316 -17.864 1.00 22.53 ? 1456 NAG A C7 1 HETATM 6758 C C8 . NAG K 4 . ? 81.270 -14.385 -18.959 1.00 21.66 ? 1456 NAG A C8 1 HETATM 6759 N N2 . NAG K 4 . ? 79.549 -15.303 -17.537 1.00 22.19 ? 1456 NAG A N2 1 HETATM 6760 O O3 . NAG K 4 . ? 78.160 -17.777 -18.028 1.00 22.20 ? 1456 NAG A O3 1 HETATM 6761 O O4 . NAG K 4 . ? 76.120 -18.435 -16.125 1.00 19.78 ? 1456 NAG A O4 1 HETATM 6762 O O5 . NAG K 4 . ? 78.340 -16.273 -14.206 1.00 19.27 ? 1456 NAG A O5 1 HETATM 6763 O O6 . NAG K 4 . ? 77.606 -18.720 -13.031 1.00 19.29 ? 1456 NAG A O6 1 HETATM 6764 O O7 . NAG K 4 . ? 81.656 -16.049 -17.311 1.00 23.49 ? 1456 NAG A O7 1 HETATM 6765 FE FE . N7H L 5 . ? 80.677 -5.915 11.240 1.00 9.05 ? 1458 N7H A FE 1 HETATM 6766 N N1 . N7H L 5 . ? 85.020 -7.413 9.781 1.00 14.22 ? 1458 N7H A N1 1 HETATM 6767 O O1 . N7H L 5 . ? 84.883 -7.925 8.484 1.00 16.91 ? 1458 N7H A O1 1 HETATM 6768 O O2 . N7H L 5 . ? 86.103 -7.410 10.347 1.00 17.15 ? 1458 N7H A O2 1 HETATM 6769 N NA . N7H L 5 . ? 82.265 -5.048 10.400 1.00 10.13 ? 1458 N7H A NA 1 HETATM 6770 N NB . N7H L 5 . ? 81.807 -7.636 11.619 1.00 10.18 ? 1458 N7H A NB 1 HETATM 6771 N NC . N7H L 5 . ? 79.046 -6.848 12.133 1.00 9.13 ? 1458 N7H A NC 1 HETATM 6772 N ND . N7H L 5 . ? 79.646 -4.355 10.928 1.00 8.90 ? 1458 N7H A ND 1 HETATM 6773 C C1A . N7H L 5 . ? 82.334 -3.733 9.998 1.00 10.14 ? 1458 N7H A C1A 1 HETATM 6774 O O1A . N7H L 5 . ? 82.995 0.332 9.289 1.00 14.77 ? 1458 N7H A O1A 1 HETATM 6775 C C1B . N7H L 5 . ? 83.084 -7.815 11.282 1.00 10.85 ? 1458 N7H A C1B 1 HETATM 6776 C C1C . N7H L 5 . ? 79.027 -8.065 12.762 1.00 9.42 ? 1458 N7H A C1C 1 HETATM 6777 C C1D . N7H L 5 . ? 78.349 -4.166 11.252 1.00 9.00 ? 1458 N7H A C1D 1 HETATM 6778 O O1D . N7H L 5 . ? 78.614 1.231 7.075 1.00 10.14 ? 1458 N7H A O1D 1 HETATM 6779 C C2A . N7H L 5 . ? 83.616 -3.476 9.468 1.00 10.79 ? 1458 N7H A C2A 1 HETATM 6780 O O2A . N7H L 5 . ? 83.667 0.451 11.340 1.00 16.39 ? 1458 N7H A O2A 1 HETATM 6781 C C2B . N7H L 5 . ? 83.531 -9.083 11.769 1.00 11.23 ? 1458 N7H A C2B 1 HETATM 6782 C C2C . N7H L 5 . ? 77.708 -8.344 13.161 1.00 9.53 ? 1458 N7H A C2C 1 HETATM 6783 C C2D . N7H L 5 . ? 77.924 -2.792 10.956 1.00 9.05 ? 1458 N7H A C2D 1 HETATM 6784 O O2D . N7H L 5 . ? 77.779 1.766 8.993 1.00 9.98 ? 1458 N7H A O2D 1 HETATM 6785 C C3A . N7H L 5 . ? 84.339 -4.618 9.572 1.00 11.09 ? 1458 N7H A C3A 1 HETATM 6786 C C3B . N7H L 5 . ? 82.494 -9.636 12.471 1.00 10.52 ? 1458 N7H A C3B 1 HETATM 6787 C C3C . N7H L 5 . ? 76.930 -7.249 12.798 1.00 9.38 ? 1458 N7H A C3C 1 HETATM 6788 C C3D . N7H L 5 . ? 79.001 -2.150 10.485 1.00 9.11 ? 1458 N7H A C3D 1 HETATM 6789 C C4A . N7H L 5 . ? 83.513 -5.593 10.179 1.00 10.91 ? 1458 N7H A C4A 1 HETATM 6790 C C4B . N7H L 5 . ? 81.383 -8.662 12.380 1.00 10.23 ? 1458 N7H A C4B 1 HETATM 6791 C C4C . N7H L 5 . ? 77.792 -6.314 12.165 1.00 9.02 ? 1458 N7H A C4C 1 HETATM 6792 C C4D . N7H L 5 . ? 80.089 -3.142 10.515 1.00 9.21 ? 1458 N7H A C4D 1 HETATM 6793 C CAA . N7H L 5 . ? 84.094 -2.167 8.888 1.00 11.44 ? 1458 N7H A CAA 1 HETATM 6794 C CAB . N7H L 5 . ? 82.436 -10.924 13.196 1.00 10.62 ? 1458 N7H A CAB 1 HETATM 6795 C CAC . N7H L 5 . ? 75.483 -7.035 13.003 1.00 9.71 ? 1458 N7H A CAC 1 HETATM 6796 C CAD . N7H L 5 . ? 79.066 -0.699 10.041 1.00 9.32 ? 1458 N7H A CAD 1 HETATM 6797 C CBA . N7H L 5 . ? 84.621 -1.276 10.012 1.00 12.30 ? 1458 N7H A CBA 1 HETATM 6798 C CBB . N7H L 5 . ? 83.498 -11.441 13.807 1.00 10.38 ? 1458 N7H A CBB 1 HETATM 6799 C CBC . N7H L 5 . ? 74.633 -8.044 13.129 1.00 11.32 ? 1458 N7H A CBC 1 HETATM 6800 C CBD . N7H L 5 . ? 78.399 -0.544 8.665 1.00 9.66 ? 1458 N7H A CBD 1 HETATM 6801 C CGA . N7H L 5 . ? 83.705 -0.101 10.223 1.00 14.51 ? 1458 N7H A CGA 1 HETATM 6802 C CGD . N7H L 5 . ? 78.279 0.901 8.234 1.00 9.48 ? 1458 N7H A CGD 1 HETATM 6803 C CHA . N7H L 5 . ? 81.347 -2.790 10.067 1.00 9.76 ? 1458 N7H A CHA 1 HETATM 6804 C CHB . N7H L 5 . ? 83.898 -6.901 10.431 1.00 12.23 ? 1458 N7H A CHB 1 HETATM 6805 C CHC . N7H L 5 . ? 80.129 -8.895 12.953 1.00 9.45 ? 1458 N7H A CHC 1 HETATM 6806 C CHD . N7H L 5 . ? 77.408 -5.091 11.700 1.00 8.94 ? 1458 N7H A CHD 1 HETATM 6807 C CMA . N7H L 5 . ? 85.770 -4.810 9.136 1.00 11.83 ? 1458 N7H A CMA 1 HETATM 6808 C CMB . N7H L 5 . ? 84.896 -9.700 11.570 1.00 11.47 ? 1458 N7H A CMB 1 HETATM 6809 C CMC . N7H L 5 . ? 77.253 -9.588 13.889 1.00 9.54 ? 1458 N7H A CMC 1 HETATM 6810 C CMD . N7H L 5 . ? 76.538 -2.220 11.133 1.00 9.05 ? 1458 N7H A CMD 1 HETATM 6811 C C . FMT M 6 . ? 73.707 -18.309 48.805 1.00 49.40 ? 1459 FMT A C 1 HETATM 6812 O O1 . FMT M 6 . ? 73.722 -19.206 47.978 1.00 48.28 ? 1459 FMT A O1 1 HETATM 6813 O O2 . FMT M 6 . ? 74.342 -17.166 48.556 1.00 44.99 ? 1459 FMT A O2 1 HETATM 6814 N N . NO2 N 7 . ? 81.402 -5.386 14.726 1.00 19.05 ? 1460 NO2 A N 1 HETATM 6815 O O1 . NO2 N 7 . ? 81.315 -5.330 13.329 1.00 16.50 ? 1460 NO2 A O1 1 HETATM 6816 O O2 . NO2 N 7 . ? 82.392 -4.945 15.287 1.00 26.41 ? 1460 NO2 A O2 1 HETATM 6817 AS AS . CAC O 2 . ? 128.749 -12.276 67.472 1.00 58.22 ? 1449 CAC B AS 1 HETATM 6818 O O1 . CAC O 2 . ? 129.581 -13.553 68.315 1.00 48.05 ? 1449 CAC B O1 1 HETATM 6819 O O2 . CAC O 2 . ? 127.219 -11.974 68.246 1.00 49.20 ? 1449 CAC B O2 1 HETATM 6820 C C1 . CAC O 2 . ? 129.842 -10.647 67.517 1.00 53.14 ? 1449 CAC B C1 1 HETATM 6821 C C2 . CAC O 2 . ? 128.446 -12.816 65.609 1.00 50.63 ? 1449 CAC B C2 1 HETATM 6822 C C1 . GOL P 3 . ? 97.510 -10.568 23.694 1.00 26.78 ? 1450 GOL B C1 1 HETATM 6823 O O1 . GOL P 3 . ? 96.283 -9.847 23.533 1.00 25.19 ? 1450 GOL B O1 1 HETATM 6824 C C2 . GOL P 3 . ? 97.405 -11.906 22.969 1.00 27.92 ? 1450 GOL B C2 1 HETATM 6825 O O2 . GOL P 3 . ? 97.676 -11.716 21.576 1.00 25.18 ? 1450 GOL B O2 1 HETATM 6826 C C3 . GOL P 3 . ? 98.419 -12.882 23.552 1.00 26.40 ? 1450 GOL B C3 1 HETATM 6827 O O3 . GOL P 3 . ? 97.993 -14.221 23.278 1.00 24.13 ? 1450 GOL B O3 1 HETATM 6828 C C1 . GOL Q 3 . ? 125.994 -47.048 43.692 1.00 29.28 ? 1451 GOL B C1 1 HETATM 6829 O O1 . GOL Q 3 . ? 127.182 -47.158 44.482 1.00 34.55 ? 1451 GOL B O1 1 HETATM 6830 C C2 . GOL Q 3 . ? 125.352 -45.689 43.950 1.00 28.86 ? 1451 GOL B C2 1 HETATM 6831 O O2 . GOL Q 3 . ? 124.226 -45.841 44.822 1.00 32.07 ? 1451 GOL B O2 1 HETATM 6832 C C3 . GOL Q 3 . ? 124.891 -45.095 42.625 1.00 23.28 ? 1451 GOL B C3 1 HETATM 6833 O O3 . GOL Q 3 . ? 123.614 -45.629 42.274 1.00 23.36 ? 1451 GOL B O3 1 HETATM 6834 C C1 . GOL R 3 . ? 115.564 -17.749 75.318 1.00 29.74 ? 1452 GOL B C1 1 HETATM 6835 O O1 . GOL R 3 . ? 116.967 -17.705 75.027 1.00 27.43 ? 1452 GOL B O1 1 HETATM 6836 C C2 . GOL R 3 . ? 114.785 -16.950 74.276 1.00 28.31 ? 1452 GOL B C2 1 HETATM 6837 O O2 . GOL R 3 . ? 115.181 -15.576 74.330 1.00 30.97 ? 1452 GOL B O2 1 HETATM 6838 C C3 . GOL R 3 . ? 113.290 -17.044 74.560 1.00 31.87 ? 1452 GOL B C3 1 HETATM 6839 O O3 . GOL R 3 . ? 112.590 -17.462 73.380 1.00 28.92 ? 1452 GOL B O3 1 HETATM 6840 C C1 . GOL S 3 . ? 99.566 -13.138 39.620 1.00 31.45 ? 1453 GOL B C1 1 HETATM 6841 O O1 . GOL S 3 . ? 99.782 -13.282 41.032 1.00 27.72 ? 1453 GOL B O1 1 HETATM 6842 C C2 . GOL S 3 . ? 99.060 -14.447 39.019 1.00 31.33 ? 1453 GOL B C2 1 HETATM 6843 O O2 . GOL S 3 . ? 98.525 -15.287 40.049 1.00 33.45 ? 1453 GOL B O2 1 HETATM 6844 C C3 . GOL S 3 . ? 97.970 -14.160 37.991 1.00 34.52 ? 1453 GOL B C3 1 HETATM 6845 O O3 . GOL S 3 . ? 96.953 -13.339 38.580 1.00 37.41 ? 1453 GOL B O3 1 HETATM 6846 C C1 . NAG T 4 . ? 130.623 -11.121 58.683 1.00 25.79 ? 1454 NAG B C1 1 HETATM 6847 C C2 . NAG T 4 . ? 131.225 -9.745 58.429 1.00 27.88 ? 1454 NAG B C2 1 HETATM 6848 C C3 . NAG T 4 . ? 132.641 -9.699 58.992 1.00 29.80 ? 1454 NAG B C3 1 HETATM 6849 C C4 . NAG T 4 . ? 132.624 -10.092 60.464 1.00 31.44 ? 1454 NAG B C4 1 HETATM 6850 C C5 . NAG T 4 . ? 131.885 -11.409 60.672 1.00 29.15 ? 1454 NAG B C5 1 HETATM 6851 C C6 . NAG T 4 . ? 131.700 -11.674 62.160 1.00 28.33 ? 1454 NAG B C6 1 HETATM 6852 C C7 . NAG T 4 . ? 130.601 -8.366 56.509 1.00 26.78 ? 1454 NAG B C7 1 HETATM 6853 C C8 . NAG T 4 . ? 130.706 -8.174 55.026 1.00 24.87 ? 1454 NAG B C8 1 HETATM 6854 N N2 . NAG T 4 . ? 131.223 -9.435 57.012 1.00 27.08 ? 1454 NAG B N2 1 HETATM 6855 O O3 . NAG T 4 . ? 133.156 -8.395 58.867 1.00 29.96 ? 1454 NAG B O3 1 HETATM 6856 O O4 . NAG T 4 . ? 133.943 -10.197 60.957 1.00 34.12 ? 1454 NAG B O4 1 HETATM 6857 O O5 . NAG T 4 . ? 130.606 -11.348 60.075 1.00 29.81 ? 1454 NAG B O5 1 HETATM 6858 O O6 . NAG T 4 . ? 131.115 -12.943 62.343 1.00 29.63 ? 1454 NAG B O6 1 HETATM 6859 O O7 . NAG T 4 . ? 129.961 -7.564 57.189 1.00 25.76 ? 1454 NAG B O7 1 HETATM 6860 C C1 . NAG U 4 . ? 90.175 -8.242 62.629 1.00 30.25 ? 1455 NAG B C1 1 HETATM 6861 C C2 . NAG U 4 . ? 88.906 -7.596 63.172 1.00 32.66 ? 1455 NAG B C2 1 HETATM 6862 C C3 . NAG U 4 . ? 89.241 -6.228 63.744 1.00 37.43 ? 1455 NAG B C3 1 HETATM 6863 C C4 . NAG U 4 . ? 90.331 -6.378 64.796 1.00 39.25 ? 1455 NAG B C4 1 HETATM 6864 C C5 . NAG U 4 . ? 91.523 -7.153 64.243 1.00 37.84 ? 1455 NAG B C5 1 HETATM 6865 C C6 . NAG U 4 . ? 92.525 -7.446 65.353 1.00 38.15 ? 1455 NAG B C6 1 HETATM 6866 C C7 . NAG U 4 . ? 86.741 -8.155 62.268 1.00 30.56 ? 1455 NAG B C7 1 HETATM 6867 C C8 . NAG U 4 . ? 85.733 -7.982 61.170 1.00 30.21 ? 1455 NAG B C8 1 HETATM 6868 N N2 . NAG U 4 . ? 87.884 -7.485 62.150 1.00 30.91 ? 1455 NAG B N2 1 HETATM 6869 O O3 . NAG U 4 . ? 88.089 -5.656 64.320 1.00 39.50 ? 1455 NAG B O3 1 HETATM 6870 O O4 . NAG U 4 . ? 90.758 -5.101 65.209 1.00 47.52 ? 1455 NAG B O4 1 HETATM 6871 O O5 . NAG U 4 . ? 91.101 -8.381 63.685 1.00 34.52 ? 1455 NAG B O5 1 HETATM 6872 O O6 . NAG U 4 . ? 92.307 -8.752 65.847 1.00 37.60 ? 1455 NAG B O6 1 HETATM 6873 O O7 . NAG U 4 . ? 86.501 -8.889 63.224 1.00 28.85 ? 1455 NAG B O7 1 HETATM 6874 FE FE . N7H V 5 . ? 110.960 -20.986 52.890 1.00 11.81 ? 1456 N7H B FE 1 HETATM 6875 N N1 . N7H V 5 . ? 108.344 -17.066 53.990 1.00 17.44 ? 1456 N7H B N1 1 HETATM 6876 O O1 . N7H V 5 . ? 108.139 -17.009 55.374 1.00 18.60 ? 1456 N7H B O1 1 HETATM 6877 O O2 . N7H V 5 . ? 107.900 -16.188 53.261 1.00 18.44 ? 1456 N7H B O2 1 HETATM 6878 N NA . N7H V 5 . ? 111.368 -19.075 53.278 1.00 13.06 ? 1456 N7H B NA 1 HETATM 6879 N NB . N7H V 5 . ? 108.917 -20.532 52.752 1.00 12.79 ? 1456 N7H B NB 1 HETATM 6880 N NC . N7H V 5 . ? 110.492 -22.970 52.473 1.00 11.82 ? 1456 N7H B NC 1 HETATM 6881 N ND . N7H V 5 . ? 112.803 -21.412 52.986 1.00 12.20 ? 1456 N7H B ND 1 HETATM 6882 C C1A . N7H V 5 . ? 112.628 -18.520 53.348 1.00 13.33 ? 1456 N7H B C1A 1 HETATM 6883 O O1A . N7H V 5 . ? 115.547 -16.277 50.849 1.00 20.20 ? 1456 N7H B O1A 1 HETATM 6884 C C1B . N7H V 5 . ? 108.376 -19.328 52.954 1.00 13.37 ? 1456 N7H B C1B 1 HETATM 6885 C C1C . N7H V 5 . ? 109.263 -23.482 52.151 1.00 11.13 ? 1456 N7H B C1C 1 HETATM 6886 C C1D . N7H V 5 . ? 113.354 -22.636 52.833 1.00 11.86 ? 1456 N7H B C1D 1 HETATM 6887 O O1D . N7H V 5 . ? 119.453 -20.849 53.657 1.00 11.71 ? 1456 N7H B O1D 1 HETATM 6888 C C2A . N7H V 5 . ? 112.510 -17.137 53.616 1.00 14.24 ? 1456 N7H B C2A 1 HETATM 6889 O O2A . N7H V 5 . ? 116.223 -16.501 52.898 1.00 18.43 ? 1456 N7H B O2A 1 HETATM 6890 C C2B . N7H V 5 . ? 106.973 -19.382 52.692 1.00 13.00 ? 1456 N7H B C2B 1 HETATM 6891 C C2C . N7H V 5 . ? 109.377 -24.872 51.997 1.00 11.15 ? 1456 N7H B C2C 1 HETATM 6892 C C2D . N7H V 5 . ? 114.820 -22.558 52.868 1.00 12.03 ? 1456 N7H B C2D 1 HETATM 6893 O O2D . N7H V 5 . ? 118.951 -19.795 55.474 1.00 11.86 ? 1456 N7H B O2D 1 HETATM 6894 C C3A . N7H V 5 . ? 111.187 -16.849 53.696 1.00 15.07 ? 1456 N7H B C3A 1 HETATM 6895 C C3B . N7H V 5 . ? 106.692 -20.658 52.287 1.00 12.05 ? 1456 N7H B C3B 1 HETATM 6896 C C3C . N7H V 5 . ? 110.704 -25.204 52.235 1.00 11.33 ? 1456 N7H B C3C 1 HETATM 6897 C C3D . N7H V 5 . ? 115.130 -21.259 53.008 1.00 12.00 ? 1456 N7H B C3D 1 HETATM 6898 C C4A . N7H V 5 . ? 110.472 -18.039 53.454 1.00 13.97 ? 1456 N7H B C4A 1 HETATM 6899 C C4B . N7H V 5 . ? 107.986 -21.381 52.291 1.00 11.91 ? 1456 N7H B C4B 1 HETATM 6900 C C4C . N7H V 5 . ? 111.393 -23.993 52.525 1.00 11.39 ? 1456 N7H B C4C 1 HETATM 6901 C C4D . N7H V 5 . ? 113.844 -20.545 53.044 1.00 11.83 ? 1456 N7H B C4D 1 HETATM 6902 C CAA . N7H V 5 . ? 113.635 -16.156 53.850 1.00 15.37 ? 1456 N7H B CAA 1 HETATM 6903 C CAB . N7H V 5 . ? 105.395 -21.235 51.887 1.00 12.42 ? 1456 N7H B CAB 1 HETATM 6904 C CAC . N7H V 5 . ? 111.320 -26.545 52.210 1.00 11.42 ? 1456 N7H B CAC 1 HETATM 6905 C CAD . N7H V 5 . ? 116.517 -20.662 53.095 1.00 11.80 ? 1456 N7H B CAD 1 HETATM 6906 C CBA . N7H V 5 . ? 114.081 -15.483 52.552 1.00 16.04 ? 1456 N7H B CBA 1 HETATM 6907 C CBB . N7H V 5 . ? 104.316 -20.478 51.703 1.00 12.98 ? 1456 N7H B CBB 1 HETATM 6908 C CBC . N7H V 5 . ? 110.586 -27.645 52.342 1.00 11.85 ? 1456 N7H B CBC 1 HETATM 6909 C CBD . N7H V 5 . ? 117.183 -21.042 54.425 1.00 11.69 ? 1456 N7H B CBD 1 HETATM 6910 C CGA . N7H V 5 . ? 115.355 -16.125 52.075 1.00 17.94 ? 1456 N7H B CGA 1 HETATM 6911 C CGD . N7H V 5 . ? 118.603 -20.524 54.514 1.00 11.92 ? 1456 N7H B CGD 1 HETATM 6912 C CHA . N7H V 5 . ? 113.825 -19.170 53.201 1.00 12.89 ? 1456 N7H B CHA 1 HETATM 6913 C CHB . N7H V 5 . ? 109.088 -18.120 53.451 1.00 14.54 ? 1456 N7H B CHB 1 HETATM 6914 C CHC . N7H V 5 . ? 108.099 -22.739 51.970 1.00 11.73 ? 1456 N7H B CHC 1 HETATM 6915 C CHD . N7H V 5 . ? 112.733 -23.883 52.756 1.00 11.65 ? 1456 N7H B CHD 1 HETATM 6916 C CMA . N7H V 5 . ? 110.590 -15.489 53.963 1.00 16.00 ? 1456 N7H B CMA 1 HETATM 6917 C CMB . N7H V 5 . ? 105.982 -18.254 52.846 1.00 13.33 ? 1456 N7H B CMB 1 HETATM 6918 C CMC . N7H V 5 . ? 108.247 -25.812 51.651 1.00 11.00 ? 1456 N7H B CMC 1 HETATM 6919 C CMD . N7H V 5 . ? 115.791 -23.711 52.765 1.00 12.05 ? 1456 N7H B CMD 1 HETATM 6920 N N . NO2 W 7 . ? 110.659 -20.933 49.273 1.00 22.96 ? 1457 NO2 B N 1 HETATM 6921 O O1 . NO2 W 7 . ? 110.930 -20.543 50.592 1.00 21.98 ? 1457 NO2 B O1 1 HETATM 6922 O O2 . NO2 W 7 . ? 110.612 -20.093 48.389 1.00 28.08 ? 1457 NO2 B O2 1 HETATM 6923 O O . HOH X 8 . ? 75.063 15.838 29.840 1.00 34.25 ? 2001 HOH A O 1 HETATM 6924 O O . HOH X 8 . ? 74.808 16.520 26.865 1.00 45.61 ? 2002 HOH A O 1 HETATM 6925 O O . HOH X 8 . ? 76.804 18.135 28.918 1.00 39.47 ? 2003 HOH A O 1 HETATM 6926 O O . HOH X 8 . ? 75.682 19.867 26.326 1.00 37.51 ? 2004 HOH A O 1 HETATM 6927 O O . HOH X 8 . ? 69.071 11.463 28.655 1.00 36.06 ? 2005 HOH A O 1 HETATM 6928 O O . HOH X 8 . ? 70.196 9.903 30.282 1.00 30.90 ? 2006 HOH A O 1 HETATM 6929 O O . HOH X 8 . ? 76.787 12.056 38.508 1.00 43.71 ? 2007 HOH A O 1 HETATM 6930 O O . HOH X 8 . ? 81.988 12.894 35.894 1.00 45.67 ? 2008 HOH A O 1 HETATM 6931 O O . HOH X 8 . ? 81.822 3.645 20.356 1.00 30.46 ? 2009 HOH A O 1 HETATM 6932 O O . HOH X 8 . ? 78.004 10.388 36.558 1.00 37.09 ? 2010 HOH A O 1 HETATM 6933 O O . HOH X 8 . ? 79.740 11.578 35.024 1.00 32.53 ? 2011 HOH A O 1 HETATM 6934 O O . HOH X 8 . ? 75.276 14.417 37.341 1.00 35.58 ? 2012 HOH A O 1 HETATM 6935 O O . HOH X 8 . ? 73.813 9.538 37.874 1.00 30.29 ? 2013 HOH A O 1 HETATM 6936 O O . HOH X 8 . ? 69.077 8.889 32.495 1.00 22.31 ? 2014 HOH A O 1 HETATM 6937 O O . HOH X 8 . ? 88.331 -0.803 22.394 1.00 30.44 ? 2015 HOH A O 1 HETATM 6938 O O . HOH X 8 . ? 96.811 2.297 33.220 1.00 38.60 ? 2016 HOH A O 1 HETATM 6939 O O . HOH X 8 . ? 94.984 9.169 33.412 1.00 29.14 ? 2017 HOH A O 1 HETATM 6940 O O . HOH X 8 . ? 99.787 -4.365 22.495 1.00 27.90 ? 2018 HOH A O 1 HETATM 6941 O O . HOH X 8 . ? 94.142 -9.941 27.473 1.00 26.43 ? 2019 HOH A O 1 HETATM 6942 O O . HOH X 8 . ? 73.237 3.778 30.586 1.00 9.65 ? 2020 HOH A O 1 HETATM 6943 O O . HOH X 8 . ? 79.578 2.182 21.383 1.00 18.94 ? 2021 HOH A O 1 HETATM 6944 O O . HOH X 8 . ? 82.663 -3.303 24.972 1.00 13.49 ? 2022 HOH A O 1 HETATM 6945 O O . HOH X 8 . ? 84.656 -0.783 24.582 1.00 15.32 ? 2023 HOH A O 1 HETATM 6946 O O . HOH X 8 . ? 66.490 -6.113 49.253 1.00 34.17 ? 2024 HOH A O 1 HETATM 6947 O O . HOH X 8 . ? 70.217 -9.930 54.008 1.00 37.96 ? 2025 HOH A O 1 HETATM 6948 O O . HOH X 8 . ? 78.417 8.387 20.344 1.00 24.46 ? 2026 HOH A O 1 HETATM 6949 O O . HOH X 8 . ? 84.432 7.718 21.148 1.00 35.11 ? 2027 HOH A O 1 HETATM 6950 O O . HOH X 8 . ? 86.291 4.154 21.757 1.00 38.08 ? 2028 HOH A O 1 HETATM 6951 O O . HOH X 8 . ? 71.678 -0.606 50.128 1.00 35.91 ? 2029 HOH A O 1 HETATM 6952 O O . HOH X 8 . ? 82.839 -4.695 52.027 1.00 34.36 ? 2030 HOH A O 1 HETATM 6953 O O . HOH X 8 . ? 80.316 -4.853 54.083 1.00 41.86 ? 2031 HOH A O 1 HETATM 6954 O O . HOH X 8 . ? 83.369 -9.212 53.708 1.00 31.12 ? 2032 HOH A O 1 HETATM 6955 O O . HOH X 8 . ? 79.550 -7.354 55.531 1.00 40.78 ? 2033 HOH A O 1 HETATM 6956 O O . HOH X 8 . ? 77.194 5.352 47.441 1.00 46.00 ? 2034 HOH A O 1 HETATM 6957 O O . HOH X 8 . ? 88.690 4.514 30.148 1.00 31.50 ? 2035 HOH A O 1 HETATM 6958 O O . HOH X 8 . ? 76.603 4.487 49.687 1.00 44.65 ? 2036 HOH A O 1 HETATM 6959 O O . HOH X 8 . ? 77.677 -4.245 53.985 1.00 44.90 ? 2037 HOH A O 1 HETATM 6960 O O . HOH X 8 . ? 86.843 0.183 43.877 1.00 39.87 ? 2038 HOH A O 1 HETATM 6961 O O . HOH X 8 . ? 88.226 -0.764 25.376 1.00 22.29 ? 2039 HOH A O 1 HETATM 6962 O O . HOH X 8 . ? 92.716 5.318 27.219 1.00 38.23 ? 2040 HOH A O 1 HETATM 6963 O O . HOH X 8 . ? 91.849 5.386 29.768 1.00 32.03 ? 2041 HOH A O 1 HETATM 6964 O O . HOH X 8 . ? 93.975 1.846 32.816 1.00 18.67 ? 2042 HOH A O 1 HETATM 6965 O O . HOH X 8 . ? 94.248 5.698 33.502 1.00 44.39 ? 2043 HOH A O 1 HETATM 6966 O O . HOH X 8 . ? 97.909 -2.438 20.874 1.00 22.64 ? 2044 HOH A O 1 HETATM 6967 O O . HOH X 8 . ? 97.222 0.372 21.045 1.00 33.62 ? 2045 HOH A O 1 HETATM 6968 O O . HOH X 8 . ? 80.583 15.430 28.327 1.00 42.55 ? 2046 HOH A O 1 HETATM 6969 O O . HOH X 8 . ? 82.631 17.684 33.437 1.00 37.54 ? 2047 HOH A O 1 HETATM 6970 O O . HOH X 8 . ? 85.982 17.774 35.600 1.00 41.79 ? 2048 HOH A O 1 HETATM 6971 O O . HOH X 8 . ? 92.118 -8.959 28.677 1.00 16.45 ? 2049 HOH A O 1 HETATM 6972 O O . HOH X 8 . ? 88.606 7.889 38.350 1.00 35.01 ? 2050 HOH A O 1 HETATM 6973 O O . HOH X 8 . ? 91.863 5.690 41.246 1.00 39.06 ? 2051 HOH A O 1 HETATM 6974 O O . HOH X 8 . ? 63.394 -16.835 30.863 1.00 21.03 ? 2052 HOH A O 1 HETATM 6975 O O . HOH X 8 . ? 63.198 -16.696 36.068 1.00 33.53 ? 2053 HOH A O 1 HETATM 6976 O O . HOH X 8 . ? 61.768 -12.077 43.766 1.00 29.41 ? 2054 HOH A O 1 HETATM 6977 O O . HOH X 8 . ? 58.961 -12.571 39.389 1.00 32.35 ? 2055 HOH A O 1 HETATM 6978 O O . HOH X 8 . ? 71.708 -18.390 41.332 1.00 47.86 ? 2056 HOH A O 1 HETATM 6979 O O . HOH X 8 . ? 60.380 -3.952 45.266 1.00 39.68 ? 2057 HOH A O 1 HETATM 6980 O O . HOH X 8 . ? 69.512 -17.791 44.954 1.00 34.86 ? 2058 HOH A O 1 HETATM 6981 O O . HOH X 8 . ? 69.348 -17.248 48.227 1.00 41.34 ? 2059 HOH A O 1 HETATM 6982 O O . HOH X 8 . ? 59.953 -9.881 44.960 1.00 34.21 ? 2060 HOH A O 1 HETATM 6983 O O . HOH X 8 . ? 55.899 -3.643 41.061 1.00 40.98 ? 2061 HOH A O 1 HETATM 6984 O O . HOH X 8 . ? 68.298 -12.403 49.950 1.00 34.14 ? 2062 HOH A O 1 HETATM 6985 O O . HOH X 8 . ? 75.741 -14.173 50.204 1.00 28.27 ? 2063 HOH A O 1 HETATM 6986 O O . HOH X 8 . ? 57.027 -0.058 34.470 1.00 36.10 ? 2064 HOH A O 1 HETATM 6987 O O . HOH X 8 . ? 54.338 0.641 32.140 1.00 40.96 ? 2065 HOH A O 1 HETATM 6988 O O . HOH X 8 . ? 54.587 -1.241 29.554 1.00 35.68 ? 2066 HOH A O 1 HETATM 6989 O O . HOH X 8 . ? 60.486 -8.971 18.347 1.00 26.83 ? 2067 HOH A O 1 HETATM 6990 O O . HOH X 8 . ? 66.539 -8.302 47.667 1.00 26.34 ? 2068 HOH A O 1 HETATM 6991 O O . HOH X 8 . ? 69.641 -5.155 50.347 1.00 29.42 ? 2069 HOH A O 1 HETATM 6992 O O . HOH X 8 . ? 72.202 -8.628 53.361 1.00 37.87 ? 2070 HOH A O 1 HETATM 6993 O O . HOH X 8 . ? 66.732 -20.330 26.745 1.00 24.11 ? 2071 HOH A O 1 HETATM 6994 O O . HOH X 8 . ? 67.815 -23.705 19.192 1.00 27.46 ? 2072 HOH A O 1 HETATM 6995 O O . HOH X 8 . ? 61.826 -13.429 16.633 1.00 39.70 ? 2073 HOH A O 1 HETATM 6996 O O . HOH X 8 . ? 74.617 -0.226 50.282 1.00 24.38 ? 2074 HOH A O 1 HETATM 6997 O O . HOH X 8 . ? 73.519 -6.668 52.786 1.00 34.50 ? 2075 HOH A O 1 HETATM 6998 O O . HOH X 8 . ? 70.571 -18.634 0.668 1.00 25.38 ? 2076 HOH A O 1 HETATM 6999 O O . HOH X 8 . ? 81.239 -3.017 50.868 1.00 35.51 ? 2077 HOH A O 1 HETATM 7000 O O . HOH X 8 . ? 81.917 -7.190 51.792 1.00 24.61 ? 2078 HOH A O 1 HETATM 7001 O O . HOH X 8 . ? 78.783 -8.724 53.154 1.00 36.03 ? 2079 HOH A O 1 HETATM 7002 O O . HOH X 8 . ? 74.877 4.167 45.219 1.00 25.46 ? 2080 HOH A O 1 HETATM 7003 O O . HOH X 8 . ? 79.707 3.770 48.753 1.00 35.46 ? 2081 HOH A O 1 HETATM 7004 O O . HOH X 8 . ? 75.149 2.569 49.695 1.00 37.16 ? 2082 HOH A O 1 HETATM 7005 O O . HOH X 8 . ? 79.064 -2.053 51.624 1.00 35.06 ? 2083 HOH A O 1 HETATM 7006 O O . HOH X 8 . ? 69.484 -19.594 37.445 1.00 27.87 ? 2084 HOH A O 1 HETATM 7007 O O . HOH X 8 . ? 65.255 -21.246 35.326 1.00 31.31 ? 2085 HOH A O 1 HETATM 7008 O O . HOH X 8 . ? 84.212 0.641 44.455 1.00 26.30 ? 2086 HOH A O 1 HETATM 7009 O O . HOH X 8 . ? 82.382 0.236 50.263 1.00 44.32 ? 2087 HOH A O 1 HETATM 7010 O O . HOH X 8 . ? 79.455 6.182 38.828 1.00 21.79 ? 2088 HOH A O 1 HETATM 7011 O O . HOH X 8 . ? 84.963 3.108 36.163 1.00 14.87 ? 2089 HOH A O 1 HETATM 7012 O O . HOH X 8 . ? 85.020 5.640 37.370 1.00 32.93 ? 2090 HOH A O 1 HETATM 7013 O O . HOH X 8 . ? 98.911 -3.356 38.540 1.00 34.59 ? 2091 HOH A O 1 HETATM 7014 O O . HOH X 8 . ? 102.021 -3.891 30.591 1.00 39.11 ? 2092 HOH A O 1 HETATM 7015 O O . HOH X 8 . ? 95.263 -2.651 41.429 1.00 29.10 ? 2093 HOH A O 1 HETATM 7016 O O . HOH X 8 . ? 83.468 15.010 29.362 1.00 24.29 ? 2094 HOH A O 1 HETATM 7017 O O . HOH X 8 . ? 83.118 -13.939 51.303 1.00 37.36 ? 2095 HOH A O 1 HETATM 7018 O O . HOH X 8 . ? 84.578 -12.946 54.493 1.00 41.81 ? 2096 HOH A O 1 HETATM 7019 O O . HOH X 8 . ? 88.857 10.527 26.512 1.00 30.61 ? 2097 HOH A O 1 HETATM 7020 O O . HOH X 8 . ? 88.876 15.570 26.974 1.00 24.59 ? 2098 HOH A O 1 HETATM 7021 O O . HOH X 8 . ? 80.829 12.126 24.536 1.00 29.40 ? 2099 HOH A O 1 HETATM 7022 O O . HOH X 8 . ? 89.975 17.636 29.615 1.00 28.25 ? 2100 HOH A O 1 HETATM 7023 O O . HOH X 8 . ? 83.921 16.205 31.540 1.00 26.07 ? 2101 HOH A O 1 HETATM 7024 O O . HOH X 8 . ? 88.193 18.351 34.077 1.00 42.65 ? 2102 HOH A O 1 HETATM 7025 O O . HOH X 8 . ? 82.641 -23.009 23.245 1.00 29.35 ? 2103 HOH A O 1 HETATM 7026 O O . HOH X 8 . ? 92.980 10.647 32.732 1.00 26.36 ? 2104 HOH A O 1 HETATM 7027 O O . HOH X 8 . ? 93.722 11.418 35.535 1.00 39.83 ? 2105 HOH A O 1 HETATM 7028 O O . HOH X 8 . ? 90.891 11.116 37.901 1.00 36.64 ? 2106 HOH A O 1 HETATM 7029 O O . HOH X 8 . ? 84.560 13.791 33.704 1.00 30.08 ? 2107 HOH A O 1 HETATM 7030 O O . HOH X 8 . ? 90.775 8.361 26.974 1.00 35.43 ? 2108 HOH A O 1 HETATM 7031 O O . HOH X 8 . ? 97.403 -5.013 6.163 1.00 25.77 ? 2109 HOH A O 1 HETATM 7032 O O . HOH X 8 . ? 94.000 4.357 10.954 1.00 23.21 ? 2110 HOH A O 1 HETATM 7033 O O . HOH X 8 . ? 89.547 2.795 38.629 1.00 20.63 ? 2111 HOH A O 1 HETATM 7034 O O . HOH X 8 . ? 90.785 5.553 38.606 1.00 22.85 ? 2112 HOH A O 1 HETATM 7035 O O . HOH X 8 . ? 92.142 -9.956 3.052 1.00 19.64 ? 2113 HOH A O 1 HETATM 7036 O O . HOH X 8 . ? 87.598 2.297 39.609 1.00 29.23 ? 2114 HOH A O 1 HETATM 7037 O O . HOH X 8 . ? 86.404 8.958 13.761 1.00 21.41 ? 2115 HOH A O 1 HETATM 7038 O O . HOH X 8 . ? 77.442 -0.727 28.923 1.00 14.72 ? 2116 HOH A O 1 HETATM 7039 O O . HOH X 8 . ? 70.209 -15.137 30.767 1.00 12.92 ? 2117 HOH A O 1 HETATM 7040 O O . HOH X 8 . ? 67.996 -11.499 28.656 1.00 9.00 ? 2118 HOH A O 1 HETATM 7041 O O . HOH X 8 . ? 67.729 -13.830 30.337 1.00 10.81 ? 2119 HOH A O 1 HETATM 7042 O O . HOH X 8 . ? 60.717 -10.183 33.124 1.00 21.42 ? 2120 HOH A O 1 HETATM 7043 O O . HOH X 8 . ? 63.033 -7.874 32.069 1.00 14.52 ? 2121 HOH A O 1 HETATM 7044 O O . HOH X 8 . ? 65.167 -14.731 30.165 1.00 12.03 ? 2122 HOH A O 1 HETATM 7045 O O . HOH X 8 . ? 65.776 -15.300 37.690 1.00 16.68 ? 2123 HOH A O 1 HETATM 7046 O O . HOH X 8 . ? 61.256 -11.551 40.869 1.00 32.52 ? 2124 HOH A O 1 HETATM 7047 O O . HOH X 8 . ? 64.518 -11.301 44.708 1.00 23.71 ? 2125 HOH A O 1 HETATM 7048 O O . HOH X 8 . ? 63.107 -5.484 43.728 1.00 17.74 ? 2126 HOH A O 1 HETATM 7049 O O . HOH X 8 . ? 64.949 -8.469 45.381 1.00 24.16 ? 2127 HOH A O 1 HETATM 7050 O O . HOH X 8 . ? 56.162 7.147 25.085 1.00 25.20 ? 2128 HOH A O 1 HETATM 7051 O O . HOH X 8 . ? 59.327 -4.411 39.762 1.00 14.34 ? 2129 HOH A O 1 HETATM 7052 O O . HOH X 8 . ? 59.466 -7.515 43.344 1.00 29.86 ? 2130 HOH A O 1 HETATM 7053 O O . HOH X 8 . ? 53.675 -1.870 27.285 1.00 35.42 ? 2131 HOH A O 1 HETATM 7054 O O . HOH X 8 . ? 52.204 -0.208 26.269 1.00 35.59 ? 2132 HOH A O 1 HETATM 7055 O O . HOH X 8 . ? 61.748 -7.609 34.479 1.00 15.56 ? 2133 HOH A O 1 HETATM 7056 O O . HOH X 8 . ? 58.159 -9.916 34.671 1.00 23.91 ? 2134 HOH A O 1 HETATM 7057 O O . HOH X 8 . ? 56.499 -5.104 37.701 1.00 21.45 ? 2135 HOH A O 1 HETATM 7058 O O . HOH X 8 . ? 56.889 -7.787 41.362 1.00 24.57 ? 2136 HOH A O 1 HETATM 7059 O O . HOH X 8 . ? 63.442 4.642 40.089 1.00 20.34 ? 2137 HOH A O 1 HETATM 7060 O O . HOH X 8 . ? 54.870 -9.541 37.823 1.00 32.48 ? 2138 HOH A O 1 HETATM 7061 O O . HOH X 8 . ? 58.994 -8.510 31.364 1.00 27.30 ? 2139 HOH A O 1 HETATM 7062 O O . HOH X 8 . ? 61.053 -7.091 30.394 1.00 15.12 ? 2140 HOH A O 1 HETATM 7063 O O . HOH X 8 . ? 59.895 -1.009 39.596 1.00 13.65 ? 2141 HOH A O 1 HETATM 7064 O O . HOH X 8 . ? 56.294 -2.743 33.718 1.00 24.86 ? 2142 HOH A O 1 HETATM 7065 O O . HOH X 8 . ? 57.022 -0.495 30.994 1.00 28.90 ? 2143 HOH A O 1 HETATM 7066 O O . HOH X 8 . ? 57.179 -1.629 28.550 1.00 30.50 ? 2144 HOH A O 1 HETATM 7067 O O . HOH X 8 . ? 56.019 -5.906 25.507 1.00 31.71 ? 2145 HOH A O 1 HETATM 7068 O O . HOH X 8 . ? 61.438 -6.597 27.860 1.00 14.25 ? 2146 HOH A O 1 HETATM 7069 O O . HOH X 8 . ? 62.483 -2.664 22.991 1.00 12.02 ? 2147 HOH A O 1 HETATM 7070 O O . HOH X 8 . ? 62.916 -5.337 20.282 1.00 11.68 ? 2148 HOH A O 1 HETATM 7071 O O . HOH X 8 . ? 61.534 -7.602 20.639 1.00 15.37 ? 2149 HOH A O 1 HETATM 7072 O O . HOH X 8 . ? 59.152 -6.483 21.716 1.00 23.20 ? 2150 HOH A O 1 HETATM 7073 O O . HOH X 8 . ? 97.222 -15.631 2.626 1.00 24.00 ? 2151 HOH A O 1 HETATM 7074 O O . HOH X 8 . ? 99.017 -13.452 4.933 1.00 43.55 ? 2152 HOH A O 1 HETATM 7075 O O . HOH X 8 . ? 99.637 -19.996 2.606 1.00 23.28 ? 2153 HOH A O 1 HETATM 7076 O O . HOH X 8 . ? 93.422 -26.993 4.806 1.00 24.41 ? 2154 HOH A O 1 HETATM 7077 O O . HOH X 8 . ? 65.169 -13.764 22.159 1.00 13.92 ? 2155 HOH A O 1 HETATM 7078 O O . HOH X 8 . ? 87.005 -17.008 -10.606 1.00 28.10 ? 2156 HOH A O 1 HETATM 7079 O O . HOH X 8 . ? 89.169 -8.433 -11.349 1.00 29.16 ? 2157 HOH A O 1 HETATM 7080 O O . HOH X 8 . ? 63.127 -17.595 27.711 1.00 15.24 ? 2158 HOH A O 1 HETATM 7081 O O . HOH X 8 . ? 67.009 -17.829 25.779 1.00 12.72 ? 2159 HOH A O 1 HETATM 7082 O O . HOH X 8 . ? 62.826 -14.835 21.112 1.00 20.83 ? 2160 HOH A O 1 HETATM 7083 O O . HOH X 8 . ? 94.873 -17.059 -13.363 1.00 31.76 ? 2161 HOH A O 1 HETATM 7084 O O . HOH X 8 . ? 94.455 -6.852 -8.561 1.00 23.19 ? 2162 HOH A O 1 HETATM 7085 O O . HOH X 8 . ? 101.257 -6.384 -10.388 1.00 40.58 ? 2163 HOH A O 1 HETATM 7086 O O . HOH X 8 . ? 93.291 -4.044 -13.144 1.00 32.58 ? 2164 HOH A O 1 HETATM 7087 O O . HOH X 8 . ? 69.506 -16.931 26.576 1.00 11.38 ? 2165 HOH A O 1 HETATM 7088 O O . HOH X 8 . ? 66.586 -21.055 19.231 1.00 20.22 ? 2166 HOH A O 1 HETATM 7089 O O . HOH X 8 . ? 64.874 -18.238 17.234 1.00 23.72 ? 2167 HOH A O 1 HETATM 7090 O O . HOH X 8 . ? 62.983 -14.979 18.438 1.00 23.67 ? 2168 HOH A O 1 HETATM 7091 O O . HOH X 8 . ? 64.843 -16.439 9.573 1.00 33.94 ? 2169 HOH A O 1 HETATM 7092 O O . HOH X 8 . ? 68.444 -15.971 9.739 1.00 17.56 ? 2170 HOH A O 1 HETATM 7093 O O . HOH X 8 . ? 89.557 -5.394 -9.957 1.00 22.01 ? 2171 HOH A O 1 HETATM 7094 O O . HOH X 8 . ? 96.831 -4.914 -8.297 1.00 22.17 ? 2172 HOH A O 1 HETATM 7095 O O . HOH X 8 . ? 93.870 -2.515 -11.135 1.00 26.86 ? 2173 HOH A O 1 HETATM 7096 O O . HOH X 8 . ? 74.946 -21.551 10.907 1.00 18.49 ? 2174 HOH A O 1 HETATM 7097 O O . HOH X 8 . ? 69.067 -18.413 2.640 1.00 20.53 ? 2175 HOH A O 1 HETATM 7098 O O . HOH X 8 . ? 70.183 -17.636 5.231 1.00 14.88 ? 2176 HOH A O 1 HETATM 7099 O O . HOH X 8 . ? 97.643 6.297 8.626 1.00 32.47 ? 2177 HOH A O 1 HETATM 7100 O O . HOH X 8 . ? 93.652 12.051 8.016 1.00 26.76 ? 2178 HOH A O 1 HETATM 7101 O O . HOH X 8 . ? 96.372 6.073 11.318 1.00 33.99 ? 2179 HOH A O 1 HETATM 7102 O O . HOH X 8 . ? 88.785 10.548 14.002 1.00 30.80 ? 2180 HOH A O 1 HETATM 7103 O O . HOH X 8 . ? 75.415 -23.109 13.159 1.00 30.55 ? 2181 HOH A O 1 HETATM 7104 O O . HOH X 8 . ? 70.999 -28.007 16.072 1.00 32.42 ? 2182 HOH A O 1 HETATM 7105 O O . HOH X 8 . ? 75.923 -25.908 24.081 1.00 38.52 ? 2183 HOH A O 1 HETATM 7106 O O . HOH X 8 . ? 72.318 -27.539 22.295 1.00 40.11 ? 2184 HOH A O 1 HETATM 7107 O O . HOH X 8 . ? 68.784 -24.563 21.476 1.00 32.56 ? 2185 HOH A O 1 HETATM 7108 O O . HOH X 8 . ? 79.843 -25.975 22.645 1.00 27.91 ? 2186 HOH A O 1 HETATM 7109 O O . HOH X 8 . ? 83.396 10.946 -3.804 1.00 21.68 ? 2187 HOH A O 1 HETATM 7110 O O . HOH X 8 . ? 86.536 10.676 -2.099 1.00 36.41 ? 2188 HOH A O 1 HETATM 7111 O O . HOH X 8 . ? 73.387 11.887 -7.811 1.00 29.54 ? 2189 HOH A O 1 HETATM 7112 O O . HOH X 8 . ? 73.315 -23.503 30.103 1.00 27.74 ? 2190 HOH A O 1 HETATM 7113 O O . HOH X 8 . ? 72.653 -21.334 31.511 1.00 28.76 ? 2191 HOH A O 1 HETATM 7114 O O . HOH X 8 . ? 72.814 -17.945 30.470 1.00 13.70 ? 2192 HOH A O 1 HETATM 7115 O O . HOH X 8 . ? 83.980 -22.270 30.163 1.00 35.37 ? 2193 HOH A O 1 HETATM 7116 O O . HOH X 8 . ? 86.334 -0.071 -10.894 1.00 23.66 ? 2194 HOH A O 1 HETATM 7117 O O . HOH X 8 . ? 85.881 -3.767 -12.543 1.00 26.48 ? 2195 HOH A O 1 HETATM 7118 O O . HOH X 8 . ? 82.907 -0.455 -15.035 1.00 24.77 ? 2196 HOH A O 1 HETATM 7119 O O . HOH X 8 . ? 72.740 -16.731 28.085 1.00 17.54 ? 2197 HOH A O 1 HETATM 7120 O O . HOH X 8 . ? 68.930 -22.147 31.562 1.00 21.63 ? 2198 HOH A O 1 HETATM 7121 O O . HOH X 8 . ? 68.507 -17.661 35.921 1.00 27.46 ? 2199 HOH A O 1 HETATM 7122 O O . HOH X 8 . ? 67.171 -19.354 34.353 1.00 31.46 ? 2200 HOH A O 1 HETATM 7123 O O . HOH X 8 . ? 71.940 -18.819 37.629 1.00 22.97 ? 2201 HOH A O 1 HETATM 7124 O O . HOH X 8 . ? 100.712 -4.608 34.658 1.00 33.22 ? 2202 HOH A O 1 HETATM 7125 O O . HOH X 8 . ? 99.267 -2.742 35.899 1.00 21.01 ? 2203 HOH A O 1 HETATM 7126 O O . HOH X 8 . ? 99.423 0.869 33.064 1.00 36.21 ? 2204 HOH A O 1 HETATM 7127 O O . HOH X 8 . ? 98.389 -6.575 30.483 1.00 20.85 ? 2205 HOH A O 1 HETATM 7128 O O . HOH X 8 . ? 99.248 -6.716 33.217 1.00 23.36 ? 2206 HOH A O 1 HETATM 7129 O O . HOH X 8 . ? 98.147 -8.829 29.490 1.00 22.95 ? 2207 HOH A O 1 HETATM 7130 O O . HOH X 8 . ? 99.373 -9.385 33.447 1.00 30.55 ? 2208 HOH A O 1 HETATM 7131 O O . HOH X 8 . ? 96.884 -4.535 39.812 1.00 28.19 ? 2209 HOH A O 1 HETATM 7132 O O . HOH X 8 . ? 100.040 -11.564 36.452 1.00 31.42 ? 2210 HOH A O 1 HETATM 7133 O O . HOH X 8 . ? 97.402 -10.666 37.193 1.00 32.67 ? 2211 HOH A O 1 HETATM 7134 O O . HOH X 8 . ? 102.824 -6.059 35.358 1.00 33.80 ? 2212 HOH A O 1 HETATM 7135 O O . HOH X 8 . ? 92.748 -2.634 39.927 1.00 27.16 ? 2213 HOH A O 1 HETATM 7136 O O . HOH X 8 . ? 91.629 -12.060 40.496 1.00 24.90 ? 2214 HOH A O 1 HETATM 7137 O O . HOH X 8 . ? 92.731 -10.676 33.122 1.00 34.03 ? 2215 HOH A O 1 HETATM 7138 O O . HOH X 8 . ? 94.739 -29.057 18.940 1.00 27.58 ? 2216 HOH A O 1 HETATM 7139 O O . HOH X 8 . ? 91.240 -3.064 43.114 1.00 33.73 ? 2217 HOH A O 1 HETATM 7140 O O . HOH X 8 . ? 97.993 -5.983 41.935 1.00 29.52 ? 2218 HOH A O 1 HETATM 7141 O O . HOH X 8 . ? 92.114 -4.818 45.703 1.00 27.39 ? 2219 HOH A O 1 HETATM 7142 O O . HOH X 8 . ? 90.598 0.540 40.175 1.00 31.70 ? 2220 HOH A O 1 HETATM 7143 O O . HOH X 8 . ? 87.861 -5.485 48.648 1.00 21.86 ? 2221 HOH A O 1 HETATM 7144 O O . HOH X 8 . ? 82.807 -14.273 45.151 1.00 32.06 ? 2222 HOH A O 1 HETATM 7145 O O . HOH X 8 . ? 87.547 -14.802 39.149 1.00 17.67 ? 2223 HOH A O 1 HETATM 7146 O O . HOH X 8 . ? 82.997 -11.257 51.818 1.00 40.21 ? 2224 HOH A O 1 HETATM 7147 O O . HOH X 8 . ? 86.550 -10.550 51.459 1.00 26.28 ? 2225 HOH A O 1 HETATM 7148 O O . HOH X 8 . ? 60.605 -10.153 6.855 1.00 30.42 ? 2226 HOH A O 1 HETATM 7149 O O . HOH X 8 . ? 78.271 -12.366 51.525 1.00 39.97 ? 2227 HOH A O 1 HETATM 7150 O O . HOH X 8 . ? 80.221 -14.189 51.442 1.00 27.74 ? 2228 HOH A O 1 HETATM 7151 O O . HOH X 8 . ? 83.497 -15.888 49.210 1.00 27.67 ? 2229 HOH A O 1 HETATM 7152 O O . HOH X 8 . ? 80.254 -17.592 45.324 1.00 31.79 ? 2230 HOH A O 1 HETATM 7153 O O . HOH X 8 . ? 82.505 -17.170 41.761 1.00 23.14 ? 2231 HOH A O 1 HETATM 7154 O O . HOH X 8 . ? 88.423 -13.764 35.106 1.00 37.72 ? 2232 HOH A O 1 HETATM 7155 O O . HOH X 8 . ? 79.846 -22.060 35.331 1.00 27.77 ? 2233 HOH A O 1 HETATM 7156 O O . HOH X 8 . ? 84.831 -20.588 24.100 1.00 24.28 ? 2234 HOH A O 1 HETATM 7157 O O . HOH X 8 . ? 86.973 -17.412 28.180 1.00 27.35 ? 2235 HOH A O 1 HETATM 7158 O O . HOH X 8 . ? 88.813 -14.751 31.013 1.00 25.59 ? 2236 HOH A O 1 HETATM 7159 O O . HOH X 8 . ? 71.370 -18.149 -3.681 1.00 29.70 ? 2237 HOH A O 1 HETATM 7160 O O . HOH X 8 . ? 89.125 -15.612 27.946 1.00 25.25 ? 2238 HOH A O 1 HETATM 7161 O O . HOH X 8 . ? 91.332 -13.465 24.941 1.00 24.76 ? 2239 HOH A O 1 HETATM 7162 O O . HOH X 8 . ? 92.924 -11.480 25.258 1.00 26.54 ? 2240 HOH A O 1 HETATM 7163 O O . HOH X 8 . ? 91.090 -9.724 31.071 1.00 20.96 ? 2241 HOH A O 1 HETATM 7164 O O . HOH X 8 . ? 93.386 -9.340 20.607 1.00 18.99 ? 2242 HOH A O 1 HETATM 7165 O O . HOH X 8 . ? 93.111 -11.019 22.596 1.00 18.36 ? 2243 HOH A O 1 HETATM 7166 O O . HOH X 8 . ? 97.201 -7.825 21.837 1.00 25.03 ? 2244 HOH A O 1 HETATM 7167 O O . HOH X 8 . ? 92.430 -4.097 17.660 1.00 12.87 ? 2245 HOH A O 1 HETATM 7168 O O . HOH X 8 . ? 97.158 -12.623 14.133 1.00 11.70 ? 2246 HOH A O 1 HETATM 7169 O O . HOH X 8 . ? 87.190 -24.105 5.676 1.00 36.45 ? 2247 HOH A O 1 HETATM 7170 O O . HOH X 8 . ? 85.604 -25.922 4.540 1.00 36.72 ? 2248 HOH A O 1 HETATM 7171 O O . HOH X 8 . ? 99.701 -0.413 19.246 1.00 26.88 ? 2249 HOH A O 1 HETATM 7172 O O . HOH X 8 . ? 103.533 -3.531 14.614 1.00 33.40 ? 2250 HOH A O 1 HETATM 7173 O O . HOH X 8 . ? 95.966 -5.655 8.487 1.00 16.33 ? 2251 HOH A O 1 HETATM 7174 O O . HOH X 8 . ? 70.277 1.155 48.481 1.00 42.50 ? 2252 HOH A O 1 HETATM 7175 O O . HOH X 8 . ? 95.768 1.214 10.426 1.00 20.75 ? 2253 HOH A O 1 HETATM 7176 O O . HOH X 8 . ? 96.908 -0.030 8.573 1.00 34.94 ? 2254 HOH A O 1 HETATM 7177 O O . HOH X 8 . ? 88.403 -9.852 15.872 1.00 10.08 ? 2255 HOH A O 1 HETATM 7178 O O . HOH X 8 . ? 92.826 -11.239 5.837 1.00 16.08 ? 2256 HOH A O 1 HETATM 7179 O O . HOH X 8 . ? 88.153 -1.775 7.319 1.00 9.30 ? 2257 HOH A O 1 HETATM 7180 O O . HOH X 8 . ? 88.831 0.084 17.030 1.00 29.15 ? 2258 HOH A O 1 HETATM 7181 O O . HOH X 8 . ? 83.612 -3.252 16.648 1.00 27.61 ? 2259 HOH A O 1 HETATM 7182 O O . HOH X 8 . ? 87.327 -4.464 17.549 1.00 20.58 ? 2260 HOH A O 1 HETATM 7183 O O . HOH X 8 . ? 89.868 -2.981 18.078 1.00 17.78 ? 2261 HOH A O 1 HETATM 7184 O O . HOH X 8 . ? 84.040 -0.536 16.858 1.00 37.27 ? 2262 HOH A O 1 HETATM 7185 O O . HOH X 8 . ? 84.065 3.450 17.171 1.00 23.17 ? 2263 HOH A O 1 HETATM 7186 O O . HOH X 8 . ? 81.467 7.057 12.390 1.00 11.45 ? 2264 HOH A O 1 HETATM 7187 O O . HOH X 8 . ? 85.282 7.516 11.712 1.00 14.60 ? 2265 HOH A O 1 HETATM 7188 O O . HOH X 8 . ? 77.928 0.864 14.056 1.00 10.74 ? 2266 HOH A O 1 HETATM 7189 O O . HOH X 8 . ? 76.837 6.062 10.316 1.00 8.47 ? 2267 HOH A O 1 HETATM 7190 O O . HOH X 8 . ? 75.184 4.113 11.274 1.00 9.10 ? 2268 HOH A O 1 HETATM 7191 O O . HOH X 8 . ? 78.367 8.270 17.580 1.00 20.76 ? 2269 HOH A O 1 HETATM 7192 O O . HOH X 8 . ? 68.307 12.936 19.243 1.00 16.80 ? 2270 HOH A O 1 HETATM 7193 O O . HOH X 8 . ? 66.689 13.869 17.310 1.00 25.49 ? 2271 HOH A O 1 HETATM 7194 O O . HOH X 8 . ? 73.916 16.745 15.929 1.00 24.01 ? 2272 HOH A O 1 HETATM 7195 O O . HOH X 8 . ? 80.324 12.215 14.656 1.00 22.89 ? 2273 HOH A O 1 HETATM 7196 O O . HOH X 8 . ? 76.837 13.070 8.182 1.00 11.88 ? 2274 HOH A O 1 HETATM 7197 O O . HOH X 8 . ? 84.002 10.360 6.235 1.00 12.88 ? 2275 HOH A O 1 HETATM 7198 O O . HOH X 8 . ? 78.024 14.031 4.671 1.00 16.31 ? 2276 HOH A O 1 HETATM 7199 O O . HOH X 8 . ? 76.401 8.536 3.437 1.00 11.40 ? 2277 HOH A O 1 HETATM 7200 O O . HOH X 8 . ? 81.918 7.901 15.030 1.00 17.45 ? 2278 HOH A O 1 HETATM 7201 O O . HOH X 8 . ? 68.618 8.281 9.722 1.00 13.61 ? 2279 HOH A O 1 HETATM 7202 O O . HOH X 8 . ? 72.049 5.372 5.643 1.00 11.01 ? 2280 HOH A O 1 HETATM 7203 O O . HOH X 8 . ? 72.638 3.533 10.096 1.00 10.59 ? 2281 HOH A O 1 HETATM 7204 O O . HOH X 8 . ? 66.377 8.157 13.644 1.00 17.68 ? 2282 HOH A O 1 HETATM 7205 O O . HOH X 8 . ? 64.028 7.801 14.738 1.00 30.19 ? 2283 HOH A O 1 HETATM 7206 O O . HOH X 8 . ? 63.539 2.967 19.963 1.00 12.89 ? 2284 HOH A O 1 HETATM 7207 O O . HOH X 8 . ? 66.822 0.431 18.101 1.00 9.24 ? 2285 HOH A O 1 HETATM 7208 O O . HOH X 8 . ? 61.100 8.833 28.200 1.00 20.98 ? 2286 HOH A O 1 HETATM 7209 O O . HOH X 8 . ? 67.019 11.887 24.530 1.00 23.95 ? 2287 HOH A O 1 HETATM 7210 O O . HOH X 8 . ? 68.551 13.817 22.615 1.00 30.95 ? 2288 HOH A O 1 HETATM 7211 O O . HOH X 8 . ? 63.302 6.276 16.819 1.00 31.88 ? 2289 HOH A O 1 HETATM 7212 O O . HOH X 8 . ? 60.125 5.574 25.135 1.00 17.19 ? 2290 HOH A O 1 HETATM 7213 O O . HOH X 8 . ? 55.060 4.661 24.354 1.00 15.83 ? 2291 HOH A O 1 HETATM 7214 O O . HOH X 8 . ? 55.142 0.615 24.235 1.00 15.91 ? 2292 HOH A O 1 HETATM 7215 O O . HOH X 8 . ? 56.082 -1.603 26.287 1.00 33.39 ? 2293 HOH A O 1 HETATM 7216 O O . HOH X 8 . ? 52.392 2.183 27.403 1.00 13.76 ? 2294 HOH A O 1 HETATM 7217 O O . HOH X 8 . ? 65.062 7.725 36.420 1.00 29.66 ? 2295 HOH A O 1 HETATM 7218 O O . HOH X 8 . ? 66.339 7.098 34.450 1.00 27.87 ? 2296 HOH A O 1 HETATM 7219 O O . HOH X 8 . ? 62.103 6.177 38.273 1.00 16.03 ? 2297 HOH A O 1 HETATM 7220 O O . HOH X 8 . ? 67.085 5.444 37.184 1.00 21.17 ? 2298 HOH A O 1 HETATM 7221 O O . HOH X 8 . ? 76.148 -13.042 14.701 1.00 14.57 ? 2299 HOH A O 1 HETATM 7222 O O . HOH X 8 . ? 89.486 -19.269 15.996 1.00 14.31 ? 2300 HOH A O 1 HETATM 7223 O O . HOH X 8 . ? 91.566 -18.476 13.675 1.00 8.79 ? 2301 HOH A O 1 HETATM 7224 O O . HOH X 8 . ? 96.155 -19.429 5.642 1.00 17.21 ? 2302 HOH A O 1 HETATM 7225 O O . HOH X 8 . ? 89.829 -22.207 3.581 1.00 20.07 ? 2303 HOH A O 1 HETATM 7226 O O . HOH X 8 . ? 89.575 -25.347 12.766 1.00 30.86 ? 2304 HOH A O 1 HETATM 7227 O O . HOH X 8 . ? 95.365 -14.329 1.579 1.00 24.04 ? 2305 HOH A O 1 HETATM 7228 O O . HOH X 8 . ? 96.556 -16.764 8.709 1.00 18.75 ? 2306 HOH A O 1 HETATM 7229 O O . HOH X 8 . ? 96.995 -11.918 6.182 1.00 36.67 ? 2307 HOH A O 1 HETATM 7230 O O . HOH X 8 . ? 96.787 -18.484 3.095 1.00 25.15 ? 2308 HOH A O 1 HETATM 7231 O O . HOH X 8 . ? 95.670 -26.402 3.706 1.00 17.73 ? 2309 HOH A O 1 HETATM 7232 O O . HOH X 8 . ? 84.459 -21.849 -3.598 1.00 29.59 ? 2310 HOH A O 1 HETATM 7233 O O . HOH X 8 . ? 93.683 -18.454 -6.963 1.00 23.72 ? 2311 HOH A O 1 HETATM 7234 O O . HOH X 8 . ? 88.970 -22.977 -5.308 1.00 36.90 ? 2312 HOH A O 1 HETATM 7235 O O . HOH X 8 . ? 90.001 -20.680 -8.593 1.00 38.63 ? 2313 HOH A O 1 HETATM 7236 O O . HOH X 8 . ? 90.180 -22.676 -0.044 1.00 26.26 ? 2314 HOH A O 1 HETATM 7237 O O . HOH X 8 . ? 86.677 -17.102 -7.919 1.00 19.80 ? 2315 HOH A O 1 HETATM 7238 O O . HOH X 8 . ? 86.425 -19.796 -7.236 1.00 14.95 ? 2316 HOH A O 1 HETATM 7239 O O . HOH X 8 . ? 87.951 -22.908 -1.788 1.00 15.01 ? 2317 HOH A O 1 HETATM 7240 O O . HOH X 8 . ? 88.470 -15.241 -12.174 1.00 30.25 ? 2318 HOH A O 1 HETATM 7241 O O . HOH X 8 . ? 91.503 -9.376 -10.931 1.00 18.95 ? 2319 HOH A O 1 HETATM 7242 O O . HOH X 8 . ? 95.224 -14.505 -13.786 1.00 23.36 ? 2320 HOH A O 1 HETATM 7243 O O . HOH X 8 . ? 94.374 -8.048 -11.118 1.00 16.28 ? 2321 HOH A O 1 HETATM 7244 O O . HOH X 8 . ? 101.590 -9.069 -11.182 1.00 31.67 ? 2322 HOH A O 1 HETATM 7245 O O . HOH X 8 . ? 95.060 -5.863 -12.910 1.00 29.19 ? 2323 HOH A O 1 HETATM 7246 O O . HOH X 8 . ? 97.640 -5.172 -12.417 1.00 27.58 ? 2324 HOH A O 1 HETATM 7247 O O . HOH X 8 . ? 99.439 -6.493 -8.299 1.00 11.73 ? 2325 HOH A O 1 HETATM 7248 O O . HOH X 8 . ? 101.748 -7.967 -4.339 1.00 30.91 ? 2326 HOH A O 1 HETATM 7249 O O . HOH X 8 . ? 101.336 -13.487 -8.231 1.00 18.46 ? 2327 HOH A O 1 HETATM 7250 O O . HOH X 8 . ? 96.774 -12.504 3.127 1.00 37.42 ? 2328 HOH A O 1 HETATM 7251 O O . HOH X 8 . ? 99.495 -15.178 1.144 1.00 16.34 ? 2329 HOH A O 1 HETATM 7252 O O . HOH X 8 . ? 102.139 -12.106 0.131 1.00 22.42 ? 2330 HOH A O 1 HETATM 7253 O O . HOH X 8 . ? 94.705 -5.470 -4.232 1.00 16.76 ? 2331 HOH A O 1 HETATM 7254 O O . HOH X 8 . ? 94.494 -17.133 -8.925 1.00 32.95 ? 2332 HOH A O 1 HETATM 7255 O O . HOH X 8 . ? 91.902 -7.525 1.960 1.00 13.49 ? 2333 HOH A O 1 HETATM 7256 O O . HOH X 8 . ? 94.219 -11.695 1.949 1.00 27.55 ? 2334 HOH A O 1 HETATM 7257 O O . HOH X 8 . ? 96.426 -8.870 3.356 1.00 23.06 ? 2335 HOH A O 1 HETATM 7258 O O . HOH X 8 . ? 85.616 -3.264 -5.458 1.00 13.87 ? 2336 HOH A O 1 HETATM 7259 O O . HOH X 8 . ? 80.312 -8.287 -9.478 1.00 13.21 ? 2337 HOH A O 1 HETATM 7260 O O . HOH X 8 . ? 82.579 0.658 0.380 1.00 10.02 ? 2338 HOH A O 1 HETATM 7261 O O . HOH X 8 . ? 81.413 1.108 7.175 1.00 13.45 ? 2339 HOH A O 1 HETATM 7262 O O . HOH X 8 . ? 93.084 -5.065 2.310 1.00 13.59 ? 2340 HOH A O 1 HETATM 7263 O O . HOH X 8 . ? 96.228 -1.876 6.928 1.00 32.58 ? 2341 HOH A O 1 HETATM 7264 O O . HOH X 8 . ? 94.366 2.908 8.691 1.00 13.24 ? 2342 HOH A O 1 HETATM 7265 O O . HOH X 8 . ? 85.003 4.761 -6.788 1.00 25.92 ? 2343 HOH A O 1 HETATM 7266 O O . HOH X 8 . ? 78.370 1.088 -5.269 1.00 11.60 ? 2344 HOH A O 1 HETATM 7267 O O . HOH X 8 . ? 78.915 6.339 -3.446 1.00 11.68 ? 2345 HOH A O 1 HETATM 7268 O O . HOH X 8 . ? 90.578 1.969 -7.074 1.00 26.32 ? 2346 HOH A O 1 HETATM 7269 O O . HOH X 8 . ? 92.272 5.425 -4.712 1.00 30.81 ? 2347 HOH A O 1 HETATM 7270 O O . HOH X 8 . ? 87.621 -4.425 -8.286 1.00 18.25 ? 2348 HOH A O 1 HETATM 7271 O O . HOH X 8 . ? 87.985 1.876 -10.480 1.00 30.44 ? 2349 HOH A O 1 HETATM 7272 O O . HOH X 8 . ? 94.943 -4.311 -6.597 1.00 24.38 ? 2350 HOH A O 1 HETATM 7273 O O . HOH X 8 . ? 92.420 -4.776 -8.857 1.00 26.71 ? 2351 HOH A O 1 HETATM 7274 O O . HOH X 8 . ? 95.577 -3.200 -2.452 1.00 25.29 ? 2352 HOH A O 1 HETATM 7275 O O . HOH X 8 . ? 97.327 0.635 -4.047 1.00 19.57 ? 2353 HOH A O 1 HETATM 7276 O O . HOH X 8 . ? 95.245 -3.989 1.906 1.00 31.76 ? 2354 HOH A O 1 HETATM 7277 O O . HOH X 8 . ? 94.113 9.473 -0.812 1.00 18.92 ? 2355 HOH A O 1 HETATM 7278 O O . HOH X 8 . ? 96.971 6.303 0.130 1.00 17.23 ? 2356 HOH A O 1 HETATM 7279 O O . HOH X 8 . ? 96.129 3.986 6.865 1.00 13.97 ? 2357 HOH A O 1 HETATM 7280 O O . HOH X 8 . ? 94.914 10.086 6.149 1.00 23.98 ? 2358 HOH A O 1 HETATM 7281 O O . HOH X 8 . ? 91.044 11.486 10.636 1.00 22.49 ? 2359 HOH A O 1 HETATM 7282 O O . HOH X 8 . ? 95.026 8.311 11.720 1.00 41.29 ? 2360 HOH A O 1 HETATM 7283 O O . HOH X 8 . ? 90.391 15.358 4.221 1.00 30.15 ? 2361 HOH A O 1 HETATM 7284 O O . HOH X 8 . ? 93.601 14.532 7.391 1.00 37.81 ? 2362 HOH A O 1 HETATM 7285 O O . HOH X 8 . ? 84.690 8.515 9.349 1.00 13.05 ? 2363 HOH A O 1 HETATM 7286 O O . HOH X 8 . ? 88.038 6.689 11.022 1.00 15.38 ? 2364 HOH A O 1 HETATM 7287 O O . HOH X 8 . ? 78.220 4.477 8.685 1.00 8.30 ? 2365 HOH A O 1 HETATM 7288 O O . HOH X 8 . ? 81.722 8.397 10.012 1.00 12.58 ? 2366 HOH A O 1 HETATM 7289 O O . HOH X 8 . ? 81.224 10.351 -2.291 1.00 18.09 ? 2367 HOH A O 1 HETATM 7290 O O . HOH X 8 . ? 79.943 14.734 2.896 1.00 18.42 ? 2368 HOH A O 1 HETATM 7291 O O . HOH X 8 . ? 85.416 12.105 0.323 1.00 23.13 ? 2369 HOH A O 1 HETATM 7292 O O . HOH X 8 . ? 79.140 9.020 -2.795 1.00 16.29 ? 2370 HOH A O 1 HETATM 7293 O O . HOH X 8 . ? 76.584 2.270 -8.291 1.00 14.18 ? 2371 HOH A O 1 HETATM 7294 O O . HOH X 8 . ? 77.590 0.841 4.485 1.00 9.97 ? 2372 HOH A O 1 HETATM 7295 O O . HOH X 8 . ? 75.197 9.867 -7.882 1.00 30.28 ? 2373 HOH A O 1 HETATM 7296 O O . HOH X 8 . ? 74.951 4.239 -9.081 1.00 14.03 ? 2374 HOH A O 1 HETATM 7297 O O . HOH X 8 . ? 83.920 7.174 -6.644 1.00 29.69 ? 2375 HOH A O 1 HETATM 7298 O O . HOH X 8 . ? 71.261 4.792 -10.643 1.00 25.23 ? 2376 HOH A O 1 HETATM 7299 O O . HOH X 8 . ? 75.772 0.695 -14.312 1.00 22.02 ? 2377 HOH A O 1 HETATM 7300 O O . HOH X 8 . ? 75.363 0.018 -6.959 1.00 13.52 ? 2378 HOH A O 1 HETATM 7301 O O . HOH X 8 . ? 67.708 -3.501 -10.590 1.00 17.06 ? 2379 HOH A O 1 HETATM 7302 O O . HOH X 8 . ? 78.652 -4.774 -11.943 1.00 17.56 ? 2380 HOH A O 1 HETATM 7303 O O . HOH X 8 . ? 74.912 -6.821 -10.912 1.00 13.37 ? 2381 HOH A O 1 HETATM 7304 O O . HOH X 8 . ? 75.611 -1.748 -14.244 1.00 23.44 ? 2382 HOH A O 1 HETATM 7305 O O . HOH X 8 . ? 79.120 -0.739 -7.075 1.00 10.39 ? 2383 HOH A O 1 HETATM 7306 O O . HOH X 8 . ? 78.880 -2.111 -13.590 1.00 23.07 ? 2384 HOH A O 1 HETATM 7307 O O . HOH X 8 . ? 80.866 -6.017 -11.135 1.00 14.52 ? 2385 HOH A O 1 HETATM 7308 O O . HOH X 8 . ? 75.104 -9.362 -5.256 1.00 11.77 ? 2386 HOH A O 1 HETATM 7309 O O . HOH X 8 . ? 73.265 -9.717 -7.596 1.00 18.09 ? 2387 HOH A O 1 HETATM 7310 O O . HOH X 8 . ? 85.874 -3.137 -9.956 1.00 19.11 ? 2388 HOH A O 1 HETATM 7311 O O . HOH X 8 . ? 83.789 0.922 -12.146 1.00 25.73 ? 2389 HOH A O 1 HETATM 7312 O O . HOH X 8 . ? 72.254 -2.948 0.922 1.00 12.04 ? 2390 HOH A O 1 HETATM 7313 O O . HOH X 8 . ? 72.543 -0.127 10.065 1.00 11.40 ? 2391 HOH A O 1 HETATM 7314 O O . HOH X 8 . ? 71.172 2.374 5.639 1.00 11.27 ? 2392 HOH A O 1 HETATM 7315 O O . HOH X 8 . ? 68.429 -1.420 -3.703 1.00 20.58 ? 2393 HOH A O 1 HETATM 7316 O O . HOH X 8 . ? 64.462 5.667 2.793 1.00 22.09 ? 2394 HOH A O 1 HETATM 7317 O O . HOH X 8 . ? 64.225 7.262 -2.078 1.00 13.82 ? 2395 HOH A O 1 HETATM 7318 O O . HOH X 8 . ? 68.992 10.269 2.632 1.00 12.24 ? 2396 HOH A O 1 HETATM 7319 O O . HOH X 8 . ? 77.287 10.278 -4.362 1.00 17.38 ? 2397 HOH A O 1 HETATM 7320 O O . HOH X 8 . ? 69.929 12.450 -4.330 1.00 21.24 ? 2398 HOH A O 1 HETATM 7321 O O . HOH X 8 . ? 65.965 6.714 8.448 1.00 16.86 ? 2399 HOH A O 1 HETATM 7322 O O . HOH X 8 . ? 64.600 4.381 5.321 1.00 21.51 ? 2400 HOH A O 1 HETATM 7323 O O . HOH X 8 . ? 71.058 1.726 8.566 1.00 10.34 ? 2401 HOH A O 1 HETATM 7324 O O . HOH X 8 . ? 64.489 4.361 9.885 1.00 18.68 ? 2402 HOH A O 1 HETATM 7325 O O . HOH X 8 . ? 64.711 1.435 16.554 1.00 13.89 ? 2403 HOH A O 1 HETATM 7326 O O . HOH X 8 . ? 68.432 -0.324 15.919 1.00 10.26 ? 2404 HOH A O 1 HETATM 7327 O O . HOH X 8 . ? 63.880 1.413 9.767 1.00 28.28 ? 2405 HOH A O 1 HETATM 7328 O O . HOH X 8 . ? 62.645 -1.739 10.605 1.00 26.60 ? 2406 HOH A O 1 HETATM 7329 O O . HOH X 8 . ? 74.351 0.728 12.282 1.00 10.63 ? 2407 HOH A O 1 HETATM 7330 O O . HOH X 8 . ? 80.864 -4.933 18.028 1.00 13.22 ? 2408 HOH A O 1 HETATM 7331 O O . HOH X 8 . ? 84.899 -0.910 19.536 1.00 34.37 ? 2409 HOH A O 1 HETATM 7332 O O . HOH X 8 . ? 95.870 -15.464 24.277 1.00 22.34 ? 2410 HOH A O 1 HETATM 7333 O O . HOH X 8 . ? 100.672 -10.156 15.279 1.00 30.09 ? 2411 HOH A O 1 HETATM 7334 O O . HOH X 8 . ? 95.822 -10.004 20.014 1.00 18.84 ? 2412 HOH A O 1 HETATM 7335 O O . HOH X 8 . ? 102.453 -14.669 16.526 1.00 34.11 ? 2413 HOH A O 1 HETATM 7336 O O . HOH X 8 . ? 102.856 -22.244 16.203 1.00 13.56 ? 2414 HOH A O 1 HETATM 7337 O O . HOH X 8 . ? 103.718 -18.566 16.536 1.00 17.54 ? 2415 HOH A O 1 HETATM 7338 O O . HOH X 8 . ? 97.221 -25.720 12.997 1.00 22.72 ? 2416 HOH A O 1 HETATM 7339 O O . HOH X 8 . ? 101.499 -26.595 10.759 1.00 21.86 ? 2417 HOH A O 1 HETATM 7340 O O . HOH X 8 . ? 97.520 -17.654 7.046 1.00 21.27 ? 2418 HOH A O 1 HETATM 7341 O O . HOH X 8 . ? 99.784 -15.600 6.426 1.00 41.66 ? 2419 HOH A O 1 HETATM 7342 O O . HOH X 8 . ? 96.858 -28.663 6.380 1.00 16.97 ? 2420 HOH A O 1 HETATM 7343 O O . HOH X 8 . ? 91.991 -24.885 6.036 1.00 31.47 ? 2421 HOH A O 1 HETATM 7344 O O . HOH X 8 . ? 95.034 -26.253 20.831 1.00 22.58 ? 2422 HOH A O 1 HETATM 7345 O O . HOH X 8 . ? 95.456 -20.121 22.862 1.00 17.72 ? 2423 HOH A O 1 HETATM 7346 O O . HOH X 8 . ? 91.336 -22.557 22.031 1.00 22.04 ? 2424 HOH A O 1 HETATM 7347 O O . HOH X 8 . ? 92.324 -19.553 22.398 1.00 19.31 ? 2425 HOH A O 1 HETATM 7348 O O . HOH X 8 . ? 60.301 1.537 16.167 1.00 25.51 ? 2426 HOH A O 1 HETATM 7349 O O . HOH X 8 . ? 63.384 3.823 16.907 1.00 31.50 ? 2427 HOH A O 1 HETATM 7350 O O . HOH X 8 . ? 59.078 -1.379 17.127 1.00 22.75 ? 2428 HOH A O 1 HETATM 7351 O O . HOH X 8 . ? 60.867 -3.601 20.146 1.00 18.52 ? 2429 HOH A O 1 HETATM 7352 O O . HOH X 8 . ? 63.058 -7.977 13.726 1.00 16.25 ? 2430 HOH A O 1 HETATM 7353 O O . HOH X 8 . ? 61.977 -9.708 16.125 1.00 33.52 ? 2431 HOH A O 1 HETATM 7354 O O . HOH X 8 . ? 64.509 -9.517 11.738 1.00 14.56 ? 2432 HOH A O 1 HETATM 7355 O O . HOH X 8 . ? 66.622 -15.409 7.585 1.00 24.91 ? 2433 HOH A O 1 HETATM 7356 O O . HOH X 8 . ? 62.996 -11.241 8.272 1.00 21.13 ? 2434 HOH A O 1 HETATM 7357 O O . HOH X 8 . ? 64.531 -3.741 5.330 1.00 17.14 ? 2435 HOH A O 1 HETATM 7358 O O . HOH X 8 . ? 67.621 -7.773 -4.812 1.00 11.68 ? 2436 HOH A O 1 HETATM 7359 O O . HOH X 8 . ? 64.991 -7.078 -8.315 1.00 18.92 ? 2437 HOH A O 1 HETATM 7360 O O . HOH X 8 . ? 66.268 -8.225 -11.837 1.00 47.78 ? 2438 HOH A O 1 HETATM 7361 O O . HOH X 8 . ? 69.053 -0.194 -6.036 1.00 17.61 ? 2439 HOH A O 1 HETATM 7362 O O . HOH X 8 . ? 67.158 -10.478 -11.821 1.00 34.85 ? 2440 HOH A O 1 HETATM 7363 O O . HOH X 8 . ? 69.252 -13.666 -9.244 1.00 20.73 ? 2441 HOH A O 1 HETATM 7364 O O . HOH X 8 . ? 74.463 -12.052 -8.848 1.00 18.03 ? 2442 HOH A O 1 HETATM 7365 O O . HOH X 8 . ? 81.290 -16.543 8.042 1.00 15.73 ? 2443 HOH A O 1 HETATM 7366 O O . HOH X 8 . ? 77.550 -14.416 12.421 1.00 18.96 ? 2444 HOH A O 1 HETATM 7367 O O . HOH X 8 . ? 78.780 -17.191 9.064 1.00 15.67 ? 2445 HOH A O 1 HETATM 7368 O O . HOH X 8 . ? 77.704 -20.039 13.556 1.00 15.49 ? 2446 HOH A O 1 HETATM 7369 O O . HOH X 8 . ? 78.464 -16.615 11.727 1.00 15.12 ? 2447 HOH A O 1 HETATM 7370 O O . HOH X 8 . ? 75.869 -21.430 7.401 1.00 12.22 ? 2448 HOH A O 1 HETATM 7371 O O . HOH X 8 . ? 73.262 -22.369 2.305 1.00 20.19 ? 2449 HOH A O 1 HETATM 7372 O O . HOH X 8 . ? 71.446 -25.350 12.467 1.00 28.08 ? 2450 HOH A O 1 HETATM 7373 O O . HOH X 8 . ? 80.605 -23.788 6.763 1.00 44.93 ? 2451 HOH A O 1 HETATM 7374 O O . HOH X 8 . ? 73.287 -19.672 0.983 1.00 16.11 ? 2452 HOH A O 1 HETATM 7375 O O . HOH X 8 . ? 72.268 -17.024 -1.235 1.00 18.01 ? 2453 HOH A O 1 HETATM 7376 O O . HOH X 8 . ? 80.272 -13.834 -5.834 1.00 10.02 ? 2454 HOH A O 1 HETATM 7377 O O . HOH X 8 . ? 80.370 -12.165 -8.879 1.00 10.38 ? 2455 HOH A O 1 HETATM 7378 O O . HOH X 8 . ? 86.767 -10.553 -11.477 1.00 15.58 ? 2456 HOH A O 1 HETATM 7379 O O . HOH X 8 . ? 80.889 -6.864 -15.364 1.00 28.21 ? 2457 HOH A O 1 HETATM 7380 O O . HOH X 8 . ? 80.944 -10.927 -17.707 1.00 27.57 ? 2458 HOH A O 1 HETATM 7381 O O . HOH X 8 . ? 82.455 -16.016 -14.316 1.00 22.32 ? 2459 HOH A O 1 HETATM 7382 O O . HOH X 8 . ? 79.026 -8.340 -14.519 1.00 17.75 ? 2460 HOH A O 1 HETATM 7383 O O . HOH X 8 . ? 75.464 -10.189 -13.993 1.00 16.50 ? 2461 HOH A O 1 HETATM 7384 O O . HOH X 8 . ? 77.209 -6.050 -13.870 1.00 21.89 ? 2462 HOH A O 1 HETATM 7385 O O . HOH X 8 . ? 77.871 -19.119 -10.479 1.00 21.33 ? 2463 HOH A O 1 HETATM 7386 O O . HOH X 8 . ? 74.333 -19.686 -7.145 1.00 25.82 ? 2464 HOH A O 1 HETATM 7387 O O . HOH X 8 . ? 82.428 -21.404 -5.077 1.00 20.41 ? 2465 HOH A O 1 HETATM 7388 O O . HOH X 8 . ? 83.572 -23.208 8.656 1.00 22.44 ? 2466 HOH A O 1 HETATM 7389 O O . HOH X 8 . ? 86.055 -21.990 7.100 1.00 29.91 ? 2467 HOH A O 1 HETATM 7390 O O . HOH X 8 . ? 73.350 4.719 41.110 1.00 17.73 ? 2468 HOH A O 1 HETATM 7391 O O . HOH X 8 . ? 68.252 1.659 46.332 1.00 30.61 ? 2469 HOH A O 1 HETATM 7392 O O . HOH X 8 . ? 72.551 4.388 46.433 1.00 29.74 ? 2470 HOH A O 1 HETATM 7393 O O . HOH X 8 . ? 66.291 4.168 39.900 1.00 13.37 ? 2471 HOH A O 1 HETATM 7394 O O . HOH X 8 . ? 67.709 -3.461 49.162 1.00 31.43 ? 2472 HOH A O 1 HETATM 7395 O O . HOH X 8 . ? 63.067 -6.025 46.117 1.00 33.65 ? 2473 HOH A O 1 HETATM 7396 O O . HOH X 8 . ? 100.649 -9.626 43.232 1.00 19.53 ? 2474 HOH A O 1 HETATM 7397 O O . HOH X 8 . ? 94.559 -11.806 40.356 1.00 26.03 ? 2475 HOH A O 1 HETATM 7398 O O . HOH X 8 . ? 97.233 -14.241 9.826 1.00 27.14 ? 2476 HOH A O 1 HETATM 7399 O O . HOH X 8 . ? 81.982 16.784 2.964 1.00 21.93 ? 2477 HOH A O 1 HETATM 7400 O O . HOH X 8 . ? 78.380 12.784 -4.756 1.00 28.70 ? 2478 HOH A O 1 HETATM 7401 O O . HOH X 8 . ? 98.350 -30.267 2.741 1.00 25.60 ? 2479 HOH A O 1 HETATM 7402 O O . HOH X 8 . ? 82.769 -18.680 -17.254 1.00 29.70 ? 2480 HOH A O 1 HETATM 7403 O O . HOH X 8 . ? 80.082 -19.508 -17.852 1.00 29.76 ? 2481 HOH A O 1 HETATM 7404 O O . HOH X 8 . ? 76.366 -20.939 -16.596 1.00 25.51 ? 2482 HOH A O 1 HETATM 7405 O O . HOH X 8 . ? 76.761 1.898 11.630 1.00 8.90 ? 2483 HOH A O 1 HETATM 7406 O O . HOH Y 8 . ? 125.785 -29.725 32.608 1.00 22.88 ? 2001 HOH B O 1 HETATM 7407 O O . HOH Y 8 . ? 129.270 -24.399 29.352 1.00 30.44 ? 2002 HOH B O 1 HETATM 7408 O O . HOH Y 8 . ? 128.056 -17.785 33.911 1.00 39.00 ? 2003 HOH B O 1 HETATM 7409 O O . HOH Y 8 . ? 129.231 -20.667 33.623 1.00 31.34 ? 2004 HOH B O 1 HETATM 7410 O O . HOH Y 8 . ? 113.235 -17.135 40.553 1.00 23.71 ? 2005 HOH B O 1 HETATM 7411 O O . HOH Y 8 . ? 122.519 -23.945 25.397 1.00 31.28 ? 2006 HOH B O 1 HETATM 7412 O O . HOH Y 8 . ? 129.364 -25.783 25.569 1.00 40.99 ? 2007 HOH B O 1 HETATM 7413 O O . HOH Y 8 . ? 122.255 -15.095 38.202 1.00 42.88 ? 2008 HOH B O 1 HETATM 7414 O O . HOH Y 8 . ? 123.349 -28.144 25.099 1.00 22.79 ? 2009 HOH B O 1 HETATM 7415 O O . HOH Y 8 . ? 126.078 -31.761 26.300 1.00 32.83 ? 2010 HOH B O 1 HETATM 7416 O O . HOH Y 8 . ? 125.059 -31.789 30.683 1.00 20.55 ? 2011 HOH B O 1 HETATM 7417 O O . HOH Y 8 . ? 111.729 -15.051 39.897 1.00 28.75 ? 2012 HOH B O 1 HETATM 7418 O O . HOH Y 8 . ? 119.127 -28.937 33.200 1.00 9.01 ? 2013 HOH B O 1 HETATM 7419 O O . HOH Y 8 . ? 117.204 -21.645 41.426 1.00 19.79 ? 2014 HOH B O 1 HETATM 7420 O O . HOH Y 8 . ? 112.164 -18.520 38.406 1.00 17.22 ? 2015 HOH B O 1 HETATM 7421 O O . HOH Y 8 . ? 110.191 -21.258 38.918 1.00 10.16 ? 2016 HOH B O 1 HETATM 7422 O O . HOH Y 8 . ? 109.415 -42.156 18.032 1.00 36.08 ? 2017 HOH B O 1 HETATM 7423 O O . HOH Y 8 . ? 116.444 -14.707 40.883 1.00 36.13 ? 2018 HOH B O 1 HETATM 7424 O O . HOH Y 8 . ? 120.278 -15.443 40.330 1.00 32.73 ? 2019 HOH B O 1 HETATM 7425 O O . HOH Y 8 . ? 115.112 -15.055 38.818 1.00 37.42 ? 2020 HOH B O 1 HETATM 7426 O O . HOH Y 8 . ? 115.391 -13.917 31.741 1.00 34.73 ? 2021 HOH B O 1 HETATM 7427 O O . HOH Y 8 . ? 109.861 -20.308 18.920 1.00 36.38 ? 2022 HOH B O 1 HETATM 7428 O O . HOH Y 8 . ? 110.779 -15.026 37.335 1.00 21.61 ? 2023 HOH B O 1 HETATM 7429 O O . HOH Y 8 . ? 114.449 -9.448 34.435 1.00 35.16 ? 2024 HOH B O 1 HETATM 7430 O O . HOH Y 8 . ? 112.060 -8.668 35.190 1.00 33.15 ? 2025 HOH B O 1 HETATM 7431 O O . HOH Y 8 . ? 115.180 -10.644 32.102 1.00 33.61 ? 2026 HOH B O 1 HETATM 7432 O O . HOH Y 8 . ? 121.412 -13.481 36.379 1.00 28.97 ? 2027 HOH B O 1 HETATM 7433 O O . HOH Y 8 . ? 110.462 -10.530 29.014 1.00 23.19 ? 2028 HOH B O 1 HETATM 7434 O O . HOH Y 8 . ? 104.518 -7.513 38.289 1.00 41.61 ? 2029 HOH B O 1 HETATM 7435 O O . HOH Y 8 . ? 106.769 -5.842 40.525 1.00 20.46 ? 2030 HOH B O 1 HETATM 7436 O O . HOH Y 8 . ? 101.617 -14.786 34.993 1.00 24.08 ? 2031 HOH B O 1 HETATM 7437 O O . HOH Y 8 . ? 96.349 -28.115 24.709 1.00 30.13 ? 2032 HOH B O 1 HETATM 7438 O O . HOH Y 8 . ? 112.714 -45.796 37.700 1.00 22.55 ? 2033 HOH B O 1 HETATM 7439 O O . HOH Y 8 . ? 103.581 -45.462 29.946 1.00 31.55 ? 2034 HOH B O 1 HETATM 7440 O O . HOH Y 8 . ? 103.301 -45.193 33.499 1.00 34.32 ? 2035 HOH B O 1 HETATM 7441 O O . HOH Y 8 . ? 100.993 -41.295 25.860 1.00 24.65 ? 2036 HOH B O 1 HETATM 7442 O O . HOH Y 8 . ? 97.505 -39.092 27.947 1.00 43.76 ? 2037 HOH B O 1 HETATM 7443 O O . HOH Y 8 . ? 98.989 -42.791 24.014 1.00 36.15 ? 2038 HOH B O 1 HETATM 7444 O O . HOH Y 8 . ? 103.258 -42.689 19.175 1.00 28.13 ? 2039 HOH B O 1 HETATM 7445 O O . HOH Y 8 . ? 98.786 -36.365 17.760 1.00 25.01 ? 2040 HOH B O 1 HETATM 7446 O O . HOH Y 8 . ? 112.475 -46.779 40.213 1.00 32.69 ? 2041 HOH B O 1 HETATM 7447 O O . HOH Y 8 . ? 113.900 -41.948 49.367 1.00 24.57 ? 2042 HOH B O 1 HETATM 7448 O O . HOH Y 8 . ? 107.639 -42.818 20.009 1.00 31.26 ? 2043 HOH B O 1 HETATM 7449 O O . HOH Y 8 . ? 109.155 -38.925 16.704 1.00 22.72 ? 2044 HOH B O 1 HETATM 7450 O O . HOH Y 8 . ? 112.212 -43.769 23.858 1.00 15.69 ? 2045 HOH B O 1 HETATM 7451 O O . HOH Y 8 . ? 110.490 -36.010 12.730 1.00 27.79 ? 2046 HOH B O 1 HETATM 7452 O O . HOH Y 8 . ? 104.126 -31.814 67.344 1.00 24.06 ? 2047 HOH B O 1 HETATM 7453 O O . HOH Y 8 . ? 116.736 -30.223 18.685 1.00 22.63 ? 2048 HOH B O 1 HETATM 7454 O O . HOH Y 8 . ? 114.123 -26.546 14.701 1.00 28.13 ? 2049 HOH B O 1 HETATM 7455 O O . HOH Y 8 . ? 97.660 -42.060 34.569 1.00 34.32 ? 2050 HOH B O 1 HETATM 7456 O O . HOH Y 8 . ? 111.377 -23.015 18.021 1.00 30.61 ? 2051 HOH B O 1 HETATM 7457 O O . HOH Y 8 . ? 119.264 -27.851 21.886 1.00 27.05 ? 2052 HOH B O 1 HETATM 7458 O O . HOH Y 8 . ? 118.252 -24.322 23.878 1.00 19.33 ? 2053 HOH B O 1 HETATM 7459 O O . HOH Y 8 . ? 113.846 -19.538 26.299 1.00 18.59 ? 2054 HOH B O 1 HETATM 7460 O O . HOH Y 8 . ? 116.343 -19.115 24.852 1.00 26.63 ? 2055 HOH B O 1 HETATM 7461 O O . HOH Y 8 . ? 103.227 -8.672 23.547 1.00 29.66 ? 2056 HOH B O 1 HETATM 7462 O O . HOH Y 8 . ? 105.826 -6.115 25.399 1.00 36.83 ? 2057 HOH B O 1 HETATM 7463 O O . HOH Y 8 . ? 103.292 -4.034 28.483 1.00 37.02 ? 2058 HOH B O 1 HETATM 7464 O O . HOH Y 8 . ? 95.696 -29.814 16.214 1.00 28.14 ? 2059 HOH B O 1 HETATM 7465 O O . HOH Y 8 . ? 123.003 -11.095 36.653 1.00 34.41 ? 2060 HOH B O 1 HETATM 7466 O O . HOH Y 8 . ? 124.757 -14.100 37.356 1.00 35.98 ? 2061 HOH B O 1 HETATM 7467 O O . HOH Y 8 . ? 92.917 -27.564 26.902 1.00 33.19 ? 2062 HOH B O 1 HETATM 7468 O O . HOH Y 8 . ? 94.599 -16.118 40.749 1.00 35.64 ? 2063 HOH B O 1 HETATM 7469 O O . HOH Y 8 . ? 110.655 -4.210 53.093 1.00 24.56 ? 2064 HOH B O 1 HETATM 7470 O O . HOH Y 8 . ? 133.454 -11.093 53.286 1.00 33.87 ? 2065 HOH B O 1 HETATM 7471 O O . HOH Y 8 . ? 106.920 -4.198 55.480 1.00 23.11 ? 2066 HOH B O 1 HETATM 7472 O O . HOH Y 8 . ? 114.332 -13.407 22.994 1.00 26.07 ? 2067 HOH B O 1 HETATM 7473 O O . HOH Y 8 . ? 112.087 -15.418 23.695 1.00 27.26 ? 2068 HOH B O 1 HETATM 7474 O O . HOH Y 8 . ? 111.259 -18.849 23.945 1.00 33.88 ? 2069 HOH B O 1 HETATM 7475 O O . HOH Y 8 . ? 118.039 -9.738 47.911 1.00 38.76 ? 2070 HOH B O 1 HETATM 7476 O O . HOH Y 8 . ? 122.219 -12.321 46.143 1.00 25.51 ? 2071 HOH B O 1 HETATM 7477 O O . HOH Y 8 . ? 113.839 -26.029 35.189 1.00 8.79 ? 2072 HOH B O 1 HETATM 7478 O O . HOH Y 8 . ? 127.548 -16.424 38.119 1.00 34.24 ? 2073 HOH B O 1 HETATM 7479 O O . HOH Y 8 . ? 102.903 -37.726 37.577 1.00 10.35 ? 2074 HOH B O 1 HETATM 7480 O O . HOH Y 8 . ? 132.591 -17.245 52.247 1.00 25.20 ? 2075 HOH B O 1 HETATM 7481 O O . HOH Y 8 . ? 104.992 -39.523 38.052 1.00 10.65 ? 2076 HOH B O 1 HETATM 7482 O O . HOH Y 8 . ? 107.220 -38.124 39.146 1.00 10.23 ? 2077 HOH B O 1 HETATM 7483 O O . HOH Y 8 . ? 110.144 -45.749 36.701 1.00 25.74 ? 2078 HOH B O 1 HETATM 7484 O O . HOH Y 8 . ? 111.833 -42.268 35.656 1.00 14.12 ? 2079 HOH B O 1 HETATM 7485 O O . HOH Y 8 . ? 106.683 -46.263 37.349 1.00 21.94 ? 2080 HOH B O 1 HETATM 7486 O O . HOH Y 8 . ? 104.939 -42.069 38.935 1.00 15.48 ? 2081 HOH B O 1 HETATM 7487 O O . HOH Y 8 . ? 129.550 -30.552 51.874 1.00 28.02 ? 2082 HOH B O 1 HETATM 7488 O O . HOH Y 8 . ? 103.062 -43.020 31.417 1.00 17.13 ? 2083 HOH B O 1 HETATM 7489 O O . HOH Y 8 . ? 128.176 -33.852 52.082 1.00 37.28 ? 2084 HOH B O 1 HETATM 7490 O O . HOH Y 8 . ? 107.585 -46.876 28.871 1.00 21.80 ? 2085 HOH B O 1 HETATM 7491 O O . HOH Y 8 . ? 111.851 -47.598 24.988 1.00 23.64 ? 2086 HOH B O 1 HETATM 7492 O O . HOH Y 8 . ? 112.036 -44.133 33.630 1.00 13.23 ? 2087 HOH B O 1 HETATM 7493 O O . HOH Y 8 . ? 115.229 -46.147 28.042 1.00 18.41 ? 2088 HOH B O 1 HETATM 7494 O O . HOH Y 8 . ? 113.777 -47.988 36.174 1.00 26.14 ? 2089 HOH B O 1 HETATM 7495 O O . HOH Y 8 . ? 111.484 -46.956 35.079 1.00 32.65 ? 2090 HOH B O 1 HETATM 7496 O O . HOH Y 8 . ? 116.032 -48.753 30.445 1.00 23.48 ? 2091 HOH B O 1 HETATM 7497 O O . HOH Y 8 . ? 113.632 -43.363 37.425 1.00 12.94 ? 2092 HOH B O 1 HETATM 7498 O O . HOH Y 8 . ? 118.247 -47.925 34.210 1.00 23.40 ? 2093 HOH B O 1 HETATM 7499 O O . HOH Y 8 . ? 120.344 -45.284 39.022 1.00 32.78 ? 2094 HOH B O 1 HETATM 7500 O O . HOH Y 8 . ? 114.011 -44.981 41.152 1.00 27.72 ? 2095 HOH B O 1 HETATM 7501 O O . HOH Y 8 . ? 116.632 -46.768 42.533 1.00 37.38 ? 2096 HOH B O 1 HETATM 7502 O O . HOH Y 8 . ? 114.225 -42.173 39.663 1.00 12.06 ? 2097 HOH B O 1 HETATM 7503 O O . HOH Y 8 . ? 116.147 -43.437 45.661 1.00 16.57 ? 2098 HOH B O 1 HETATM 7504 O O . HOH Y 8 . ? 118.399 -39.286 43.378 1.00 12.18 ? 2099 HOH B O 1 HETATM 7505 O O . HOH Y 8 . ? 116.120 -39.241 46.527 1.00 12.17 ? 2100 HOH B O 1 HETATM 7506 O O . HOH Y 8 . ? 95.724 -6.629 60.256 1.00 35.96 ? 2101 HOH B O 1 HETATM 7507 O O . HOH Y 8 . ? 114.372 -41.389 46.855 1.00 12.23 ? 2102 HOH B O 1 HETATM 7508 O O . HOH Y 8 . ? 107.256 -40.370 46.161 1.00 11.31 ? 2103 HOH B O 1 HETATM 7509 O O . HOH Y 8 . ? 102.186 -40.376 43.549 1.00 13.85 ? 2104 HOH B O 1 HETATM 7510 O O . HOH Y 8 . ? 103.159 -43.762 41.617 1.00 27.77 ? 2105 HOH B O 1 HETATM 7511 O O . HOH Y 8 . ? 109.189 -0.634 69.928 1.00 44.42 ? 2106 HOH B O 1 HETATM 7512 O O . HOH Y 8 . ? 97.251 -1.950 64.978 1.00 34.99 ? 2107 HOH B O 1 HETATM 7513 O O . HOH Y 8 . ? 102.026 -37.954 42.183 1.00 12.85 ? 2108 HOH B O 1 HETATM 7514 O O . HOH Y 8 . ? 101.367 -4.396 58.422 1.00 36.36 ? 2109 HOH B O 1 HETATM 7515 O O . HOH Y 8 . ? 106.534 -4.096 58.154 1.00 28.90 ? 2110 HOH B O 1 HETATM 7516 O O . HOH Y 8 . ? 108.717 -5.288 59.694 1.00 27.06 ? 2111 HOH B O 1 HETATM 7517 O O . HOH Y 8 . ? 100.348 -40.021 50.445 1.00 19.66 ? 2112 HOH B O 1 HETATM 7518 O O . HOH Y 8 . ? 105.246 -42.534 51.595 1.00 30.19 ? 2113 HOH B O 1 HETATM 7519 O O . HOH Y 8 . ? 99.706 -41.585 42.999 1.00 19.84 ? 2114 HOH B O 1 HETATM 7520 O O . HOH Y 8 . ? 107.496 -41.819 50.441 1.00 15.13 ? 2115 HOH B O 1 HETATM 7521 O O . HOH Y 8 . ? 109.820 -3.804 55.560 1.00 24.33 ? 2116 HOH B O 1 HETATM 7522 O O . HOH Y 8 . ? 115.986 -5.486 49.042 1.00 33.16 ? 2117 HOH B O 1 HETATM 7523 O O . HOH Y 8 . ? 105.955 -34.986 58.522 1.00 17.94 ? 2118 HOH B O 1 HETATM 7524 O O . HOH Y 8 . ? 106.934 -38.264 59.301 1.00 27.45 ? 2119 HOH B O 1 HETATM 7525 O O . HOH Y 8 . ? 98.791 -30.876 57.180 1.00 23.33 ? 2120 HOH B O 1 HETATM 7526 O O . HOH Y 8 . ? 107.287 -35.773 63.176 1.00 31.46 ? 2121 HOH B O 1 HETATM 7527 O O . HOH Y 8 . ? 104.488 -33.064 62.648 1.00 17.73 ? 2122 HOH B O 1 HETATM 7528 O O . HOH Y 8 . ? 104.298 -33.382 65.358 1.00 25.75 ? 2123 HOH B O 1 HETATM 7529 O O . HOH Y 8 . ? 118.779 0.640 62.324 1.00 38.34 ? 2124 HOH B O 1 HETATM 7530 O O . HOH Y 8 . ? 119.580 0.355 51.323 1.00 40.33 ? 2125 HOH B O 1 HETATM 7531 O O . HOH Y 8 . ? 96.132 -35.425 57.165 1.00 37.08 ? 2126 HOH B O 1 HETATM 7532 O O . HOH Y 8 . ? 95.699 -38.648 51.030 1.00 30.08 ? 2127 HOH B O 1 HETATM 7533 O O . HOH Y 8 . ? 96.254 -39.723 45.778 1.00 25.73 ? 2128 HOH B O 1 HETATM 7534 O O . HOH Y 8 . ? 92.555 -26.591 44.987 1.00 37.22 ? 2129 HOH B O 1 HETATM 7535 O O . HOH Y 8 . ? 92.279 -37.052 41.576 1.00 36.17 ? 2130 HOH B O 1 HETATM 7536 O O . HOH Y 8 . ? 118.741 -20.624 79.337 1.00 48.00 ? 2131 HOH B O 1 HETATM 7537 O O . HOH Y 8 . ? 121.114 -19.505 80.407 1.00 42.93 ? 2132 HOH B O 1 HETATM 7538 O O . HOH Y 8 . ? 96.353 -37.399 37.829 1.00 26.05 ? 2133 HOH B O 1 HETATM 7539 O O . HOH Y 8 . ? 99.476 -36.250 38.229 1.00 12.80 ? 2134 HOH B O 1 HETATM 7540 O O . HOH Y 8 . ? 91.715 -28.366 38.771 1.00 24.30 ? 2135 HOH B O 1 HETATM 7541 O O . HOH Y 8 . ? 89.175 -30.131 37.081 1.00 35.30 ? 2136 HOH B O 1 HETATM 7542 O O . HOH Y 8 . ? 118.534 -9.066 72.045 1.00 28.65 ? 2137 HOH B O 1 HETATM 7543 O O . HOH Y 8 . ? 120.256 -11.144 78.710 1.00 32.57 ? 2138 HOH B O 1 HETATM 7544 O O . HOH Y 8 . ? 100.912 -35.132 40.265 1.00 21.51 ? 2139 HOH B O 1 HETATM 7545 O O . HOH Y 8 . ? 96.838 -41.328 38.299 1.00 21.06 ? 2140 HOH B O 1 HETATM 7546 O O . HOH Y 8 . ? 100.220 -41.259 33.520 1.00 17.39 ? 2141 HOH B O 1 HETATM 7547 O O . HOH Y 8 . ? 102.932 -43.627 38.751 1.00 25.90 ? 2142 HOH B O 1 HETATM 7548 O O . HOH Y 8 . ? 98.607 -42.553 36.832 1.00 32.35 ? 2143 HOH B O 1 HETATM 7549 O O . HOH Y 8 . ? 97.691 -38.458 31.613 1.00 13.83 ? 2144 HOH B O 1 HETATM 7550 O O . HOH Y 8 . ? 126.674 -27.786 69.258 1.00 34.32 ? 2145 HOH B O 1 HETATM 7551 O O . HOH Y 8 . ? 131.002 -27.969 58.421 1.00 26.02 ? 2146 HOH B O 1 HETATM 7552 O O . HOH Y 8 . ? 134.119 -24.618 57.863 1.00 26.09 ? 2147 HOH B O 1 HETATM 7553 O O . HOH Y 8 . ? 103.810 -7.842 25.851 1.00 24.66 ? 2148 HOH B O 1 HETATM 7554 O O . HOH Y 8 . ? 100.698 -8.452 29.076 1.00 22.72 ? 2149 HOH B O 1 HETATM 7555 O O . HOH Y 8 . ? 101.566 -8.370 31.901 1.00 26.33 ? 2150 HOH B O 1 HETATM 7556 O O . HOH Y 8 . ? 102.352 -11.294 22.963 1.00 25.87 ? 2151 HOH B O 1 HETATM 7557 O O . HOH Y 8 . ? 101.747 -6.516 27.182 1.00 29.72 ? 2152 HOH B O 1 HETATM 7558 O O . HOH Y 8 . ? 84.971 -4.588 54.260 1.00 37.82 ? 2153 HOH B O 1 HETATM 7559 O O . HOH Y 8 . ? 105.387 -14.674 22.848 1.00 22.65 ? 2154 HOH B O 1 HETATM 7560 O O . HOH Y 8 . ? 83.149 -9.558 58.171 1.00 35.15 ? 2155 HOH B O 1 HETATM 7561 O O . HOH Y 8 . ? 96.798 -18.311 24.705 1.00 25.46 ? 2156 HOH B O 1 HETATM 7562 O O . HOH Y 8 . ? 99.356 -15.702 31.569 1.00 29.27 ? 2157 HOH B O 1 HETATM 7563 O O . HOH Y 8 . ? 84.212 -15.545 53.687 1.00 38.56 ? 2158 HOH B O 1 HETATM 7564 O O . HOH Y 8 . ? 102.699 -16.926 18.254 1.00 20.59 ? 2159 HOH B O 1 HETATM 7565 O O . HOH Y 8 . ? 107.248 -22.372 19.466 1.00 31.78 ? 2160 HOH B O 1 HETATM 7566 O O . HOH Y 8 . ? 95.932 -23.014 27.243 1.00 19.18 ? 2161 HOH B O 1 HETATM 7567 O O . HOH Y 8 . ? 98.011 -28.438 15.198 1.00 28.15 ? 2162 HOH B O 1 HETATM 7568 O O . HOH Y 8 . ? 106.403 -33.470 71.340 1.00 31.82 ? 2163 HOH B O 1 HETATM 7569 O O . HOH Y 8 . ? 97.063 -32.491 15.837 1.00 29.45 ? 2164 HOH B O 1 HETATM 7570 O O . HOH Y 8 . ? 94.526 -35.341 15.568 1.00 44.88 ? 2165 HOH B O 1 HETATM 7571 O O . HOH Y 8 . ? 95.969 -37.673 15.839 1.00 41.67 ? 2166 HOH B O 1 HETATM 7572 O O . HOH Y 8 . ? 96.946 -34.985 14.757 1.00 43.29 ? 2167 HOH B O 1 HETATM 7573 O O . HOH Y 8 . ? 94.062 -31.650 24.129 1.00 34.42 ? 2168 HOH B O 1 HETATM 7574 O O . HOH Y 8 . ? 112.233 -34.035 75.054 1.00 41.10 ? 2169 HOH B O 1 HETATM 7575 O O . HOH Y 8 . ? 94.734 -29.174 25.915 1.00 18.82 ? 2170 HOH B O 1 HETATM 7576 O O . HOH Y 8 . ? 92.474 -28.785 29.619 1.00 22.42 ? 2171 HOH B O 1 HETATM 7577 O O . HOH Y 8 . ? 92.565 -28.038 34.789 1.00 19.02 ? 2172 HOH B O 1 HETATM 7578 O O . HOH Y 8 . ? 95.376 -22.030 38.500 1.00 22.10 ? 2173 HOH B O 1 HETATM 7579 O O . HOH Y 8 . ? 94.767 -21.798 41.224 1.00 30.51 ? 2174 HOH B O 1 HETATM 7580 O O . HOH Y 8 . ? 92.679 -24.805 41.664 1.00 38.61 ? 2175 HOH B O 1 HETATM 7581 O O . HOH Y 8 . ? 96.800 -20.221 34.663 1.00 28.85 ? 2176 HOH B O 1 HETATM 7582 O O . HOH Y 8 . ? 93.587 -24.730 63.285 1.00 37.74 ? 2177 HOH B O 1 HETATM 7583 O O . HOH Y 8 . ? 105.281 -30.298 71.184 1.00 25.23 ? 2178 HOH B O 1 HETATM 7584 O O . HOH Y 8 . ? 96.440 -19.443 37.625 1.00 16.75 ? 2179 HOH B O 1 HETATM 7585 O O . HOH Y 8 . ? 96.918 -17.595 39.888 1.00 33.70 ? 2180 HOH B O 1 HETATM 7586 O O . HOH Y 8 . ? 100.604 -16.502 33.289 1.00 24.28 ? 2181 HOH B O 1 HETATM 7587 O O . HOH Y 8 . ? 102.073 -11.932 42.773 1.00 18.29 ? 2182 HOH B O 1 HETATM 7588 O O . HOH Y 8 . ? 113.555 -9.866 75.770 1.00 30.37 ? 2183 HOH B O 1 HETATM 7589 O O . HOH Y 8 . ? 112.260 -7.933 74.129 1.00 37.79 ? 2184 HOH B O 1 HETATM 7590 O O . HOH Y 8 . ? 107.623 -10.882 44.766 1.00 11.93 ? 2185 HOH B O 1 HETATM 7591 O O . HOH Y 8 . ? 100.197 -9.840 50.478 1.00 32.52 ? 2186 HOH B O 1 HETATM 7592 O O . HOH Y 8 . ? 98.822 -8.155 49.371 1.00 17.87 ? 2187 HOH B O 1 HETATM 7593 O O . HOH Y 8 . ? 101.802 -5.449 50.866 1.00 31.65 ? 2188 HOH B O 1 HETATM 7594 O O . HOH Y 8 . ? 102.410 -2.887 46.934 1.00 34.43 ? 2189 HOH B O 1 HETATM 7595 O O . HOH Y 8 . ? 105.466 -3.200 40.012 1.00 30.08 ? 2190 HOH B O 1 HETATM 7596 O O . HOH Y 8 . ? 104.585 -0.232 46.511 1.00 38.22 ? 2191 HOH B O 1 HETATM 7597 O O . HOH Y 8 . ? 111.640 -4.668 46.591 1.00 29.35 ? 2192 HOH B O 1 HETATM 7598 O O . HOH Y 8 . ? 108.742 -3.467 50.990 1.00 22.81 ? 2193 HOH B O 1 HETATM 7599 O O . HOH Y 8 . ? 107.337 4.216 47.620 1.00 15.26 ? 2194 HOH B O 1 HETATM 7600 O O . HOH Y 8 . ? 106.213 -6.154 53.595 1.00 18.36 ? 2195 HOH B O 1 HETATM 7601 O O . HOH Y 8 . ? 112.361 -4.801 49.723 1.00 25.37 ? 2196 HOH B O 1 HETATM 7602 O O . HOH Y 8 . ? 103.894 -15.894 48.131 1.00 11.92 ? 2197 HOH B O 1 HETATM 7603 O O . HOH Y 8 . ? 101.603 -8.301 52.624 1.00 37.86 ? 2198 HOH B O 1 HETATM 7604 O O . HOH Y 8 . ? 112.845 -11.846 54.687 1.00 12.34 ? 2199 HOH B O 1 HETATM 7605 O O . HOH Y 8 . ? 115.242 -10.858 46.634 1.00 34.29 ? 2200 HOH B O 1 HETATM 7606 O O . HOH Y 8 . ? 111.385 -18.734 46.362 1.00 31.17 ? 2201 HOH B O 1 HETATM 7607 O O . HOH Y 8 . ? 109.333 -12.851 44.197 1.00 14.38 ? 2202 HOH B O 1 HETATM 7608 O O . HOH Y 8 . ? 117.615 -16.235 44.778 1.00 22.50 ? 2203 HOH B O 1 HETATM 7609 O O . HOH Y 8 . ? 122.433 -16.540 48.666 1.00 13.00 ? 2204 HOH B O 1 HETATM 7610 O O . HOH Y 8 . ? 121.696 -12.708 48.709 1.00 17.19 ? 2205 HOH B O 1 HETATM 7611 O O . HOH Y 8 . ? 117.568 -22.116 49.186 1.00 12.31 ? 2206 HOH B O 1 HETATM 7612 O O . HOH Y 8 . ? 123.569 -20.796 51.399 1.00 11.90 ? 2207 HOH B O 1 HETATM 7613 O O . HOH Y 8 . ? 113.811 -17.968 45.537 1.00 33.68 ? 2208 HOH B O 1 HETATM 7614 O O . HOH Y 8 . ? 122.138 -23.086 51.405 1.00 10.96 ? 2209 HOH B O 1 HETATM 7615 O O . HOH Y 8 . ? 123.374 -19.925 44.317 1.00 22.95 ? 2210 HOH B O 1 HETATM 7616 O O . HOH Y 8 . ? 131.276 -28.387 42.662 1.00 15.21 ? 2211 HOH B O 1 HETATM 7617 O O . HOH Y 8 . ? 131.253 -26.141 39.665 1.00 27.09 ? 2212 HOH B O 1 HETATM 7618 O O . HOH Y 8 . ? 132.919 -21.292 44.045 1.00 22.62 ? 2213 HOH B O 1 HETATM 7619 O O . HOH Y 8 . ? 133.125 -29.232 44.411 1.00 23.12 ? 2214 HOH B O 1 HETATM 7620 O O . HOH Y 8 . ? 135.564 -22.803 38.385 1.00 37.18 ? 2215 HOH B O 1 HETATM 7621 O O . HOH Y 8 . ? 127.745 -16.215 41.890 1.00 32.70 ? 2216 HOH B O 1 HETATM 7622 O O . HOH Y 8 . ? 129.778 -15.560 40.164 1.00 37.46 ? 2217 HOH B O 1 HETATM 7623 O O . HOH Y 8 . ? 126.785 -16.763 45.391 1.00 23.80 ? 2218 HOH B O 1 HETATM 7624 O O . HOH Y 8 . ? 133.477 -15.229 48.151 1.00 24.67 ? 2219 HOH B O 1 HETATM 7625 O O . HOH Y 8 . ? 130.689 -12.187 47.336 1.00 25.26 ? 2220 HOH B O 1 HETATM 7626 O O . HOH Y 8 . ? 130.320 -18.106 51.907 1.00 14.74 ? 2221 HOH B O 1 HETATM 7627 O O . HOH Y 8 . ? 132.569 -14.469 51.358 1.00 38.07 ? 2222 HOH B O 1 HETATM 7628 O O . HOH Y 8 . ? 125.646 -11.914 53.534 1.00 16.35 ? 2223 HOH B O 1 HETATM 7629 O O . HOH Y 8 . ? 131.439 -15.858 54.937 1.00 15.95 ? 2224 HOH B O 1 HETATM 7630 O O . HOH Y 8 . ? 127.037 -18.974 57.542 1.00 12.75 ? 2225 HOH B O 1 HETATM 7631 O O . HOH Y 8 . ? 122.400 -16.369 46.082 1.00 16.90 ? 2226 HOH B O 1 HETATM 7632 O O . HOH Y 8 . ? 128.733 -27.512 52.598 1.00 13.86 ? 2227 HOH B O 1 HETATM 7633 O O . HOH Y 8 . ? 122.584 -25.575 52.926 1.00 12.65 ? 2228 HOH B O 1 HETATM 7634 O O . HOH Y 8 . ? 125.320 -24.430 56.743 1.00 14.41 ? 2229 HOH B O 1 HETATM 7635 O O . HOH Y 8 . ? 128.677 -30.285 49.179 1.00 17.00 ? 2230 HOH B O 1 HETATM 7636 O O . HOH Y 8 . ? 133.103 -32.051 49.352 1.00 32.06 ? 2231 HOH B O 1 HETATM 7637 O O . HOH Y 8 . ? 128.583 -33.179 48.648 1.00 21.54 ? 2232 HOH B O 1 HETATM 7638 O O . HOH Y 8 . ? 123.553 -35.978 45.001 1.00 12.11 ? 2233 HOH B O 1 HETATM 7639 O O . HOH Y 8 . ? 120.362 -33.239 46.840 1.00 9.14 ? 2234 HOH B O 1 HETATM 7640 O O . HOH Y 8 . ? 128.686 -37.801 35.999 1.00 29.48 ? 2235 HOH B O 1 HETATM 7641 O O . HOH Y 8 . ? 130.125 -30.875 38.014 1.00 21.68 ? 2236 HOH B O 1 HETATM 7642 O O . HOH Y 8 . ? 131.584 -29.019 39.773 1.00 27.83 ? 2237 HOH B O 1 HETATM 7643 O O . HOH Y 8 . ? 131.917 -37.161 40.664 1.00 21.50 ? 2238 HOH B O 1 HETATM 7644 O O . HOH Y 8 . ? 126.519 -39.194 39.739 1.00 14.82 ? 2239 HOH B O 1 HETATM 7645 O O . HOH Y 8 . ? 127.679 -43.708 40.992 1.00 22.12 ? 2240 HOH B O 1 HETATM 7646 O O . HOH Y 8 . ? 125.163 -36.375 27.756 1.00 24.28 ? 2241 HOH B O 1 HETATM 7647 O O . HOH Y 8 . ? 124.549 -39.721 26.680 1.00 18.42 ? 2242 HOH B O 1 HETATM 7648 O O . HOH Y 8 . ? 121.707 -35.423 27.139 1.00 14.86 ? 2243 HOH B O 1 HETATM 7649 O O . HOH Y 8 . ? 105.382 -27.868 51.730 1.00 15.39 ? 2244 HOH B O 1 HETATM 7650 O O . HOH Y 8 . ? 90.593 -19.702 49.570 1.00 30.22 ? 2245 HOH B O 1 HETATM 7651 O O . HOH Y 8 . ? 94.727 -17.632 50.105 1.00 13.84 ? 2246 HOH B O 1 HETATM 7652 O O . HOH Y 8 . ? 95.235 -14.956 51.776 1.00 11.45 ? 2247 HOH B O 1 HETATM 7653 O O . HOH Y 8 . ? 94.085 -9.395 58.889 1.00 21.19 ? 2248 HOH B O 1 HETATM 7654 O O . HOH Y 8 . ? 93.825 -15.343 62.497 1.00 25.08 ? 2249 HOH B O 1 HETATM 7655 O O . HOH Y 8 . ? 99.694 -8.373 62.010 1.00 23.28 ? 2250 HOH B O 1 HETATM 7656 O O . HOH Y 8 . ? 101.614 -8.804 59.734 1.00 24.46 ? 2251 HOH B O 1 HETATM 7657 O O . HOH Y 8 . ? 95.358 -7.873 57.436 1.00 25.76 ? 2252 HOH B O 1 HETATM 7658 O O . HOH Y 8 . ? 98.438 -8.114 54.108 1.00 32.67 ? 2253 HOH B O 1 HETATM 7659 O O . HOH Y 8 . ? 93.931 -15.053 65.810 1.00 26.91 ? 2254 HOH B O 1 HETATM 7660 O O . HOH Y 8 . ? 101.893 -14.527 73.057 1.00 28.65 ? 2255 HOH B O 1 HETATM 7661 O O . HOH Y 8 . ? 94.952 -16.710 68.161 1.00 29.49 ? 2256 HOH B O 1 HETATM 7662 O O . HOH Y 8 . ? 99.160 -16.089 73.230 1.00 25.55 ? 2257 HOH B O 1 HETATM 7663 O O . HOH Y 8 . ? 109.717 -8.862 73.239 1.00 29.29 ? 2258 HOH B O 1 HETATM 7664 O O . HOH Y 8 . ? 110.720 -7.068 76.859 1.00 31.17 ? 2259 HOH B O 1 HETATM 7665 O O . HOH Y 8 . ? 109.137 0.913 73.118 1.00 26.79 ? 2260 HOH B O 1 HETATM 7666 O O . HOH Y 8 . ? 105.866 0.861 69.176 1.00 33.45 ? 2261 HOH B O 1 HETATM 7667 O O . HOH Y 8 . ? 99.356 -1.043 66.584 1.00 27.58 ? 2262 HOH B O 1 HETATM 7668 O O . HOH Y 8 . ? 98.295 -6.278 60.961 1.00 36.54 ? 2263 HOH B O 1 HETATM 7669 O O . HOH Y 8 . ? 98.185 -2.414 62.460 1.00 33.50 ? 2264 HOH B O 1 HETATM 7670 O O . HOH Y 8 . ? 108.506 -4.604 65.515 1.00 31.24 ? 2265 HOH B O 1 HETATM 7671 O O . HOH Y 8 . ? 107.110 -9.184 60.722 1.00 19.96 ? 2266 HOH B O 1 HETATM 7672 O O . HOH Y 8 . ? 104.324 -8.228 60.360 1.00 21.69 ? 2267 HOH B O 1 HETATM 7673 O O . HOH Y 8 . ? 104.022 -5.141 58.966 1.00 33.81 ? 2268 HOH B O 1 HETATM 7674 O O . HOH Y 8 . ? 108.683 -3.393 62.070 1.00 35.57 ? 2269 HOH B O 1 HETATM 7675 O O . HOH Y 8 . ? 104.479 -2.333 60.368 1.00 33.13 ? 2270 HOH B O 1 HETATM 7676 O O . HOH Y 8 . ? 114.948 -12.382 67.615 1.00 22.52 ? 2271 HOH B O 1 HETATM 7677 O O . HOH Y 8 . ? 118.146 -15.107 61.460 1.00 14.63 ? 2272 HOH B O 1 HETATM 7678 O O . HOH Y 8 . ? 117.843 -17.399 55.130 1.00 14.35 ? 2273 HOH B O 1 HETATM 7679 O O . HOH Y 8 . ? 108.959 -7.727 59.781 1.00 18.94 ? 2274 HOH B O 1 HETATM 7680 O O . HOH Y 8 . ? 110.778 -5.188 57.828 1.00 20.22 ? 2275 HOH B O 1 HETATM 7681 O O . HOH Y 8 . ? 103.725 -6.298 54.765 1.00 21.48 ? 2276 HOH B O 1 HETATM 7682 O O . HOH Y 8 . ? 114.765 -5.236 51.434 1.00 28.19 ? 2277 HOH B O 1 HETATM 7683 O O . HOH Y 8 . ? 123.136 -10.025 67.014 1.00 34.27 ? 2278 HOH B O 1 HETATM 7684 O O . HOH Y 8 . ? 121.124 -17.660 67.434 1.00 18.05 ? 2279 HOH B O 1 HETATM 7685 O O . HOH Y 8 . ? 125.566 -15.740 64.358 1.00 22.06 ? 2280 HOH B O 1 HETATM 7686 O O . HOH Y 8 . ? 122.967 -7.250 67.867 1.00 29.18 ? 2281 HOH B O 1 HETATM 7687 O O . HOH Y 8 . ? 122.257 -5.295 65.790 1.00 40.74 ? 2282 HOH B O 1 HETATM 7688 O O . HOH Y 8 . ? 119.932 -3.606 64.109 1.00 28.74 ? 2283 HOH B O 1 HETATM 7689 O O . HOH Y 8 . ? 112.727 -2.832 69.899 1.00 28.33 ? 2284 HOH B O 1 HETATM 7690 O O . HOH Y 8 . ? 115.221 -3.306 70.217 1.00 28.78 ? 2285 HOH B O 1 HETATM 7691 O O . HOH Y 8 . ? 111.919 -1.886 64.269 1.00 34.57 ? 2286 HOH B O 1 HETATM 7692 O O . HOH Y 8 . ? 118.207 -1.350 63.802 1.00 40.73 ? 2287 HOH B O 1 HETATM 7693 O O . HOH Y 8 . ? 111.433 -1.171 59.358 1.00 27.22 ? 2288 HOH B O 1 HETATM 7694 O O . HOH Y 8 . ? 118.530 0.387 58.173 1.00 28.34 ? 2289 HOH B O 1 HETATM 7695 O O . HOH Y 8 . ? 122.862 -1.537 58.673 1.00 33.76 ? 2290 HOH B O 1 HETATM 7696 O O . HOH Y 8 . ? 123.266 -4.106 62.149 1.00 38.75 ? 2291 HOH B O 1 HETATM 7697 O O . HOH Y 8 . ? 123.955 -0.815 60.903 1.00 35.82 ? 2292 HOH B O 1 HETATM 7698 O O . HOH Y 8 . ? 115.624 -3.233 52.979 1.00 28.91 ? 2293 HOH B O 1 HETATM 7699 O O . HOH Y 8 . ? 121.821 -1.807 52.245 1.00 26.57 ? 2294 HOH B O 1 HETATM 7700 O O . HOH Y 8 . ? 119.101 -7.806 48.972 1.00 36.22 ? 2295 HOH B O 1 HETATM 7701 O O . HOH Y 8 . ? 122.924 -6.178 47.993 1.00 26.61 ? 2296 HOH B O 1 HETATM 7702 O O . HOH Y 8 . ? 123.334 -12.472 50.814 1.00 16.89 ? 2297 HOH B O 1 HETATM 7703 O O . HOH Y 8 . ? 132.160 -10.900 49.124 1.00 27.92 ? 2298 HOH B O 1 HETATM 7704 O O . HOH Y 8 . ? 131.812 -7.451 51.840 1.00 31.22 ? 2299 HOH B O 1 HETATM 7705 O O . HOH Y 8 . ? 127.184 -6.295 59.529 1.00 29.87 ? 2300 HOH B O 1 HETATM 7706 O O . HOH Y 8 . ? 120.159 -10.389 49.152 1.00 21.85 ? 2301 HOH B O 1 HETATM 7707 O O . HOH Y 8 . ? 121.775 -19.583 53.257 1.00 12.02 ? 2302 HOH B O 1 HETATM 7708 O O . HOH Y 8 . ? 124.001 -15.331 50.719 1.00 14.94 ? 2303 HOH B O 1 HETATM 7709 O O . HOH Y 8 . ? 128.309 -12.775 62.027 1.00 18.72 ? 2304 HOH B O 1 HETATM 7710 O O . HOH Y 8 . ? 131.858 -13.764 56.470 1.00 21.22 ? 2305 HOH B O 1 HETATM 7711 O O . HOH Y 8 . ? 127.530 -8.803 58.538 1.00 27.71 ? 2306 HOH B O 1 HETATM 7712 O O . HOH Y 8 . ? 127.673 -15.289 63.135 1.00 25.94 ? 2307 HOH B O 1 HETATM 7713 O O . HOH Y 8 . ? 123.352 -18.237 70.332 1.00 18.82 ? 2308 HOH B O 1 HETATM 7714 O O . HOH Y 8 . ? 119.434 -20.471 58.303 1.00 12.52 ? 2309 HOH B O 1 HETATM 7715 O O . HOH Y 8 . ? 129.877 -15.856 64.577 1.00 26.78 ? 2310 HOH B O 1 HETATM 7716 O O . HOH Y 8 . ? 126.035 -19.042 70.478 1.00 19.16 ? 2311 HOH B O 1 HETATM 7717 O O . HOH Y 8 . ? 129.540 -19.303 73.055 1.00 34.35 ? 2312 HOH B O 1 HETATM 7718 O O . HOH Y 8 . ? 127.366 -11.697 71.347 1.00 33.38 ? 2313 HOH B O 1 HETATM 7719 O O . HOH Y 8 . ? 122.905 -18.377 76.728 1.00 26.00 ? 2314 HOH B O 1 HETATM 7720 O O . HOH Y 8 . ? 121.408 -20.312 69.606 1.00 18.03 ? 2315 HOH B O 1 HETATM 7721 O O . HOH Y 8 . ? 115.833 -22.141 75.286 1.00 28.91 ? 2316 HOH B O 1 HETATM 7722 O O . HOH Y 8 . ? 117.003 -19.267 77.496 1.00 43.76 ? 2317 HOH B O 1 HETATM 7723 O O . HOH Y 8 . ? 120.773 -19.528 77.313 1.00 31.67 ? 2318 HOH B O 1 HETATM 7724 O O . HOH Y 8 . ? 119.477 -17.093 69.430 1.00 18.60 ? 2319 HOH B O 1 HETATM 7725 O O . HOH Y 8 . ? 112.342 -24.038 70.475 1.00 22.54 ? 2320 HOH B O 1 HETATM 7726 O O . HOH Y 8 . ? 113.024 -24.786 72.947 1.00 23.14 ? 2321 HOH B O 1 HETATM 7727 O O . HOH Y 8 . ? 116.423 -10.414 72.304 1.00 28.02 ? 2322 HOH B O 1 HETATM 7728 O O . HOH Y 8 . ? 120.019 -10.346 73.830 1.00 34.90 ? 2323 HOH B O 1 HETATM 7729 O O . HOH Y 8 . ? 119.467 -12.865 76.754 1.00 32.14 ? 2324 HOH B O 1 HETATM 7730 O O . HOH Y 8 . ? 118.181 -25.747 63.237 1.00 16.59 ? 2325 HOH B O 1 HETATM 7731 O O . HOH Y 8 . ? 119.297 -26.690 53.833 1.00 12.56 ? 2326 HOH B O 1 HETATM 7732 O O . HOH Y 8 . ? 122.916 -26.243 57.675 1.00 14.54 ? 2327 HOH B O 1 HETATM 7733 O O . HOH Y 8 . ? 127.732 -26.237 66.794 1.00 19.27 ? 2328 HOH B O 1 HETATM 7734 O O . HOH Y 8 . ? 122.180 -28.235 67.765 1.00 21.47 ? 2329 HOH B O 1 HETATM 7735 O O . HOH Y 8 . ? 128.744 -30.130 60.328 1.00 24.02 ? 2330 HOH B O 1 HETATM 7736 O O . HOH Y 8 . ? 130.607 -26.377 65.992 1.00 24.45 ? 2331 HOH B O 1 HETATM 7737 O O . HOH Y 8 . ? 131.671 -25.240 58.590 1.00 17.93 ? 2332 HOH B O 1 HETATM 7738 O O . HOH Y 8 . ? 134.278 -22.610 64.814 1.00 22.96 ? 2333 HOH B O 1 HETATM 7739 O O . HOH Y 8 . ? 134.087 -21.989 57.234 1.00 23.24 ? 2334 HOH B O 1 HETATM 7740 O O . HOH Y 8 . ? 128.490 -30.238 54.559 1.00 22.15 ? 2335 HOH B O 1 HETATM 7741 O O . HOH Y 8 . ? 127.041 -31.465 58.419 1.00 21.75 ? 2336 HOH B O 1 HETATM 7742 O O . HOH Y 8 . ? 121.764 -27.109 55.037 1.00 12.33 ? 2337 HOH B O 1 HETATM 7743 O O . HOH Y 8 . ? 126.586 -32.658 53.829 1.00 25.07 ? 2338 HOH B O 1 HETATM 7744 O O . HOH Y 8 . ? 119.572 -31.637 48.804 1.00 9.96 ? 2339 HOH B O 1 HETATM 7745 O O . HOH Y 8 . ? 122.213 -34.527 48.459 1.00 13.53 ? 2340 HOH B O 1 HETATM 7746 O O . HOH Y 8 . ? 121.715 -33.898 58.047 1.00 20.63 ? 2341 HOH B O 1 HETATM 7747 O O . HOH Y 8 . ? 120.498 -36.155 54.719 1.00 24.25 ? 2342 HOH B O 1 HETATM 7748 O O . HOH Y 8 . ? 119.146 -25.098 51.336 1.00 11.78 ? 2343 HOH B O 1 HETATM 7749 O O . HOH Y 8 . ? 110.565 -21.818 46.258 1.00 16.08 ? 2344 HOH B O 1 HETATM 7750 O O . HOH Y 8 . ? 112.455 -17.159 43.572 1.00 31.36 ? 2345 HOH B O 1 HETATM 7751 O O . HOH Y 8 . ? 99.898 -4.441 47.361 1.00 23.66 ? 2346 HOH B O 1 HETATM 7752 O O . HOH Y 8 . ? 97.599 -5.914 50.333 1.00 30.99 ? 2347 HOH B O 1 HETATM 7753 O O . HOH Y 8 . ? 90.592 -4.119 47.614 1.00 22.38 ? 2348 HOH B O 1 HETATM 7754 O O . HOH Y 8 . ? 86.314 -3.140 50.347 1.00 38.93 ? 2349 HOH B O 1 HETATM 7755 O O . HOH Y 8 . ? 85.052 -7.160 54.980 1.00 31.56 ? 2350 HOH B O 1 HETATM 7756 O O . HOH Y 8 . ? 84.686 -7.313 57.899 1.00 26.69 ? 2351 HOH B O 1 HETATM 7757 O O . HOH Y 8 . ? 88.296 -11.206 62.898 1.00 22.40 ? 2352 HOH B O 1 HETATM 7758 O O . HOH Y 8 . ? 86.561 -11.497 53.915 1.00 29.16 ? 2353 HOH B O 1 HETATM 7759 O O . HOH Y 8 . ? 83.867 -13.708 56.969 1.00 50.68 ? 2354 HOH B O 1 HETATM 7760 O O . HOH Y 8 . ? 86.350 -17.198 53.010 1.00 29.11 ? 2355 HOH B O 1 HETATM 7761 O O . HOH Y 8 . ? 90.870 -13.878 43.009 1.00 26.06 ? 2356 HOH B O 1 HETATM 7762 O O . HOH Y 8 . ? 90.266 -17.642 44.279 1.00 25.65 ? 2357 HOH B O 1 HETATM 7763 O O . HOH Y 8 . ? 92.586 -16.084 43.447 1.00 21.10 ? 2358 HOH B O 1 HETATM 7764 O O . HOH Y 8 . ? 124.632 -35.102 47.413 1.00 21.99 ? 2359 HOH B O 1 HETATM 7765 O O . HOH Y 8 . ? 124.227 -38.289 49.307 1.00 24.25 ? 2360 HOH B O 1 HETATM 7766 O O . HOH Y 8 . ? 118.666 -40.632 46.684 1.00 18.33 ? 2361 HOH B O 1 HETATM 7767 O O . HOH Y 8 . ? 121.575 -40.742 49.472 1.00 27.29 ? 2362 HOH B O 1 HETATM 7768 O O . HOH Y 8 . ? 114.602 -38.683 53.648 1.00 25.06 ? 2363 HOH B O 1 HETATM 7769 O O . HOH Y 8 . ? 118.664 -38.267 53.913 1.00 33.04 ? 2364 HOH B O 1 HETATM 7770 O O . HOH Y 8 . ? 111.637 -40.576 54.228 1.00 33.68 ? 2365 HOH B O 1 HETATM 7771 O O . HOH Y 8 . ? 112.790 -37.142 55.491 1.00 18.66 ? 2366 HOH B O 1 HETATM 7772 O O . HOH Y 8 . ? 107.791 -35.907 60.381 1.00 23.93 ? 2367 HOH B O 1 HETATM 7773 O O . HOH Y 8 . ? 118.939 -34.488 60.769 1.00 33.11 ? 2368 HOH B O 1 HETATM 7774 O O . HOH Y 8 . ? 107.409 -34.330 65.596 1.00 22.77 ? 2369 HOH B O 1 HETATM 7775 O O . HOH Y 8 . ? 114.738 -36.442 65.496 1.00 33.03 ? 2370 HOH B O 1 HETATM 7776 O O . HOH Y 8 . ? 107.592 -35.690 67.812 1.00 30.82 ? 2371 HOH B O 1 HETATM 7777 O O . HOH Y 8 . ? 108.302 -35.536 70.372 1.00 32.52 ? 2372 HOH B O 1 HETATM 7778 O O . HOH Y 8 . ? 109.155 -33.916 72.043 1.00 26.41 ? 2373 HOH B O 1 HETATM 7779 O O . HOH Y 8 . ? 116.610 -30.412 70.799 1.00 16.38 ? 2374 HOH B O 1 HETATM 7780 O O . HOH Y 8 . ? 123.853 -28.536 72.262 1.00 27.97 ? 2375 HOH B O 1 HETATM 7781 O O . HOH Y 8 . ? 123.126 -26.521 69.740 1.00 23.33 ? 2376 HOH B O 1 HETATM 7782 O O . HOH Y 8 . ? 111.643 -30.948 76.098 1.00 42.79 ? 2377 HOH B O 1 HETATM 7783 O O . HOH Y 8 . ? 109.247 -29.818 76.209 1.00 38.04 ? 2378 HOH B O 1 HETATM 7784 O O . HOH Y 8 . ? 101.463 -22.834 58.195 1.00 16.91 ? 2379 HOH B O 1 HETATM 7785 O O . HOH Y 8 . ? 101.642 -25.632 57.721 1.00 22.55 ? 2380 HOH B O 1 HETATM 7786 O O . HOH Y 8 . ? 103.960 -26.656 53.919 1.00 24.08 ? 2381 HOH B O 1 HETATM 7787 O O . HOH Y 8 . ? 98.914 -28.145 54.098 1.00 21.06 ? 2382 HOH B O 1 HETATM 7788 O O . HOH Y 8 . ? 101.362 -26.277 55.181 1.00 23.69 ? 2383 HOH B O 1 HETATM 7789 O O . HOH Y 8 . ? 99.082 -29.230 60.531 1.00 16.70 ? 2384 HOH B O 1 HETATM 7790 O O . HOH Y 8 . ? 95.577 -25.793 61.696 1.00 37.13 ? 2385 HOH B O 1 HETATM 7791 O O . HOH Y 8 . ? 97.702 -29.587 68.353 1.00 36.66 ? 2386 HOH B O 1 HETATM 7792 O O . HOH Y 8 . ? 102.429 -29.556 66.937 1.00 21.95 ? 2387 HOH B O 1 HETATM 7793 O O . HOH Y 8 . ? 105.381 -29.591 68.562 1.00 26.39 ? 2388 HOH B O 1 HETATM 7794 O O . HOH Y 8 . ? 106.604 -20.114 71.198 1.00 21.05 ? 2389 HOH B O 1 HETATM 7795 O O . HOH Y 8 . ? 105.896 -28.781 73.332 1.00 28.29 ? 2390 HOH B O 1 HETATM 7796 O O . HOH Y 8 . ? 108.613 -19.142 73.531 1.00 25.09 ? 2391 HOH B O 1 HETATM 7797 O O . HOH Y 8 . ? 115.597 -11.276 74.698 1.00 34.74 ? 2392 HOH B O 1 HETATM 7798 O O . HOH Y 8 . ? 110.943 -24.389 74.655 1.00 29.25 ? 2393 HOH B O 1 HETATM 7799 O O . HOH Y 8 . ? 109.527 -26.044 76.389 1.00 30.97 ? 2394 HOH B O 1 HETATM 7800 O O . HOH Y 8 . ? 110.216 -26.073 78.724 1.00 32.15 ? 2395 HOH B O 1 HETATM 7801 O O . HOH Y 8 . ? 103.619 -22.329 77.389 1.00 34.06 ? 2396 HOH B O 1 HETATM 7802 O O . HOH Y 8 . ? 102.145 -19.001 75.646 1.00 38.84 ? 2397 HOH B O 1 HETATM 7803 O O . HOH Y 8 . ? 103.171 -25.201 77.547 1.00 44.83 ? 2398 HOH B O 1 HETATM 7804 O O . HOH Y 8 . ? 98.640 -20.944 71.804 1.00 23.33 ? 2399 HOH B O 1 HETATM 7805 O O . HOH Y 8 . ? 97.826 -27.492 70.138 1.00 34.77 ? 2400 HOH B O 1 HETATM 7806 O O . HOH Y 8 . ? 94.248 -23.256 59.078 1.00 26.04 ? 2401 HOH B O 1 HETATM 7807 O O . HOH Y 8 . ? 96.873 -29.587 55.410 1.00 30.73 ? 2402 HOH B O 1 HETATM 7808 O O . HOH Y 8 . ? 118.457 -30.683 22.780 1.00 13.51 ? 2403 HOH B O 1 HETATM 7809 O O . HOH Y 8 . ? 121.031 -33.307 21.744 1.00 25.25 ? 2404 HOH B O 1 HETATM 7810 O O . HOH Y 8 . ? 120.582 -37.155 25.073 1.00 12.89 ? 2405 HOH B O 1 HETATM 7811 O O . HOH Y 8 . ? 111.781 -40.560 17.608 1.00 34.29 ? 2406 HOH B O 1 HETATM 7812 O O . HOH Y 8 . ? 123.612 -48.025 41.049 1.00 24.13 ? 2407 HOH B O 1 HETATM 7813 O O . HOH Y 8 . ? 132.653 -11.104 55.811 1.00 27.02 ? 2408 HOH B O 1 HETATM 7814 O O . HOH Y 8 . ? 119.421 -22.273 51.313 1.00 12.08 ? 2409 HOH B O 1 HETATM 7815 O O . HOH Y 8 . ? 111.942 -7.887 79.584 1.00 41.91 ? 2410 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 SER 1 3 3 SER SER A . n A 1 2 LEU 2 4 4 LEU LEU A . n A 1 3 ASN 3 5 5 ASN ASN A . n A 1 4 THR 4 6 6 THR THR A . n A 1 5 ASP 5 7 7 ASP ASP A . n A 1 6 ASP 6 8 8 ASP ASP A . n A 1 7 ILE 7 9 9 ILE ILE A . n A 1 8 GLN 8 10 10 GLN GLN A . n A 1 9 GLY 9 11 11 GLY GLY A . n A 1 10 ASP 10 12 12 ASP ASP A . n A 1 11 ILE 11 13 13 ILE ILE A . n A 1 12 LEU 12 14 14 LEU LEU A . n A 1 13 VAL 13 15 15 VAL VAL A . n A 1 14 GLY 14 16 16 GLY GLY A . n A 1 15 MET 15 17 17 MET MET A . n A 1 16 HIS 16 18 18 HIS HIS A . n A 1 17 LYS 17 19 19 LYS LYS A . n A 1 18 GLN 18 20 20 GLN GLN A . n A 1 19 LYS 19 21 21 LYS LYS A . n A 1 20 GLN 20 22 22 GLN GLN A . n A 1 21 LEU 21 23 23 LEU LEU A . n A 1 22 PHE 22 24 24 PHE PHE A . n A 1 23 TYR 23 25 25 TYR TYR A . n A 1 24 PHE 24 26 26 PHE PHE A . n A 1 25 PHE 25 27 27 PHE PHE A . n A 1 26 ALA 26 28 28 ALA ALA A . n A 1 27 ILE 27 29 29 ILE ILE A . n A 1 28 ASN 28 30 30 ASN ASN A . n A 1 29 ASP 29 31 31 ASP ASP A . n A 1 30 PRO 30 32 32 PRO PRO A . n A 1 31 ALA 31 33 33 ALA ALA A . n A 1 32 THR 32 34 34 THR THR A . n A 1 33 PHE 33 35 35 PHE PHE A . n A 1 34 LYS 34 36 36 LYS LYS A . n A 1 35 THR 35 37 37 THR THR A . n A 1 36 HIS 36 38 38 HIS HIS A . n A 1 37 LEU 37 39 39 LEU LEU A . n A 1 38 ALA 38 40 40 ALA ALA A . n A 1 39 SER 39 41 41 SER SER A . n A 1 40 ASP 40 42 42 ASP ASP A . n A 1 41 ILE 41 43 43 ILE ILE A . n A 1 42 ALA 42 44 44 ALA ALA A . n A 1 43 PRO 43 45 45 PRO PRO A . n A 1 44 VAL 44 46 46 VAL VAL A . n A 1 45 VAL 45 47 47 VAL VAL A . n A 1 46 ALA 46 48 48 ALA ALA A . n A 1 47 SER 47 49 49 SER SER A . n A 1 48 VAL 48 50 50 VAL VAL A . n A 1 49 THR 49 51 51 THR THR A . n A 1 50 GLN 50 52 52 GLN GLN A . n A 1 51 LEU 51 53 53 LEU LEU A . n A 1 52 SER 52 54 54 SER SER A . n A 1 53 ASN 53 55 55 ASN ASN A . n A 1 54 VAL 54 56 56 VAL VAL A . n A 1 55 ALA 55 57 57 ALA ALA A . n A 1 56 THR 56 58 58 THR THR A . n A 1 57 GLN 57 59 59 GLN GLN A . n A 1 58 PRO 58 60 60 PRO PRO A . n A 1 59 LEU 59 61 61 LEU LEU A . n A 1 60 VAL 60 62 62 VAL VAL A . n A 1 61 ALA 61 63 63 ALA ALA A . n A 1 62 LEU 62 64 64 LEU LEU A . n A 1 63 ASN 63 65 65 ASN ASN A . n A 1 64 ILE 64 66 66 ILE ILE A . n A 1 65 ALA 65 67 67 ALA ALA A . n A 1 66 PHE 66 68 68 PHE PHE A . n A 1 67 SER 67 69 69 SER SER A . n A 1 68 ASN 68 70 70 ASN ASN A . n A 1 69 THR 69 71 71 THR THR A . n A 1 70 GLY 70 72 72 GLY GLY A . n A 1 71 LEU 71 73 73 LEU LEU A . n A 1 72 LEU 72 74 74 LEU LEU A . n A 1 73 ALA 73 75 75 ALA ALA A . n A 1 74 LEU 74 76 76 LEU LEU A . n A 1 75 GLY 75 77 77 GLY GLY A . n A 1 76 VAL 76 78 78 VAL VAL A . n A 1 77 THR 77 79 79 THR THR A . n A 1 78 ASP 78 80 80 ASP ASP A . n A 1 79 ASN 79 81 81 ASN ASN A . n A 1 80 LEU 80 82 82 LEU LEU A . n A 1 81 GLY 81 83 83 GLY GLY A . n A 1 82 ASP 82 84 84 ASP ASP A . n A 1 83 SER 83 85 85 SER SER A . n A 1 84 LEU 84 86 86 LEU LEU A . n A 1 85 PHE 85 87 87 PHE PHE A . n A 1 86 ALA 86 88 88 ALA ALA A . n A 1 87 ASN 87 89 89 ASN ASN A . n A 1 88 GLY 88 90 90 GLY GLY A . n A 1 89 GLN 89 91 91 GLN GLN A . n A 1 90 ALA 90 92 92 ALA ALA A . n A 1 91 LYS 91 93 93 LYS LYS A . n A 1 92 ASP 92 94 94 ASP ASP A . n A 1 93 ALA 93 95 95 ALA ALA A . n A 1 94 THR 94 96 96 THR THR A . n A 1 95 SER 95 97 97 SER SER A . n A 1 96 PHE 96 98 98 PHE PHE A . n A 1 97 LYS 97 99 99 LYS LYS A . n A 1 98 GLU 98 100 100 GLU GLU A . n A 1 99 SER 99 101 101 SER SER A . n A 1 100 THR 100 102 102 THR THR A . n A 1 101 SER 101 103 103 SER SER A . n A 1 102 SER 102 104 104 SER SER A . n A 1 103 TRP 103 105 105 TRP TRP A . n A 1 104 VAL 104 106 106 VAL VAL A . n A 1 105 PRO 105 107 107 PRO PRO A . n A 1 106 GLN 106 108 108 GLN GLN A . n A 1 107 PHE 107 109 109 PHE PHE A . n A 1 108 ALA 108 110 110 ALA ALA A . n A 1 109 GLY 109 111 111 GLY GLY A . n A 1 110 THR 110 112 112 THR THR A . n A 1 111 GLY 111 113 113 GLY GLY A . n A 1 112 ILE 112 114 114 ILE ILE A . n A 1 113 HIS 113 115 115 HIS HIS A . n A 1 114 GLY 114 116 116 GLY GLY A . n A 1 115 VAL 115 117 117 VAL VAL A . n A 1 116 ILE 116 118 118 ILE ILE A . n A 1 117 ILE 117 119 119 ILE ILE A . n A 1 118 LEU 118 120 120 LEU LEU A . n A 1 119 ALA 119 121 121 ALA ALA A . n A 1 120 SER 120 122 122 SER SER A . n A 1 121 ASP 121 123 123 ASP ASP A . n A 1 122 THR 122 124 124 THR THR A . n A 1 123 THR 123 125 125 THR THR A . n A 1 124 ASP 124 126 126 ASP ASP A . n A 1 125 LEU 125 127 127 LEU LEU A . n A 1 126 ILE 126 128 128 ILE ILE A . n A 1 127 ASP 127 129 129 ASP ASP A . n A 1 128 GLN 128 130 130 GLN GLN A . n A 1 129 GLN 129 131 131 GLN GLN A . n A 1 130 VAL 130 132 132 VAL VAL A . n A 1 131 ALA 131 133 133 ALA ALA A . n A 1 132 SER 132 134 134 SER SER A . n A 1 133 ILE 133 135 135 ILE ILE A . n A 1 134 GLU 134 136 136 GLU GLU A . n A 1 135 SER 135 137 137 SER SER A . n A 1 136 THR 136 138 138 THR THR A . n A 1 137 PHE 137 139 139 PHE PHE A . n A 1 138 GLY 138 140 140 GLY GLY A . n A 1 139 SER 139 141 141 SER SER A . n A 1 140 SER 140 142 142 SER SER A . n A 1 141 ILE 141 143 143 ILE ILE A . n A 1 142 SER 142 144 144 SER SER A . n A 1 143 LYS 143 145 145 LYS LYS A . n A 1 144 LEU 144 146 146 LEU LEU A . n A 1 145 TYR 145 147 147 TYR TYR A . n A 1 146 SER 146 148 148 SER SER A . n A 1 147 LEU 147 149 149 LEU LEU A . n A 1 148 SER 148 150 150 SER SER A . n A 1 149 ALA 149 151 151 ALA ALA A . n A 1 150 SER 150 152 152 SER SER A . n A 1 151 ILE 151 153 153 ILE ILE A . n A 1 152 ARG 152 154 154 ARG ARG A . n A 1 153 PRO 153 155 155 PRO PRO A . n A 1 154 GLY 154 156 156 GLY GLY A . n A 1 155 ASN 155 157 157 ASN ASN A . n A 1 156 GLU 156 158 158 GLU GLU A . n A 1 157 ALA 157 159 159 ALA ALA A . n A 1 158 GLY 158 160 160 GLY GLY A . n A 1 159 HIS 159 161 161 HIS HIS A . n A 1 160 GLU 160 162 162 GLU GLU A . n A 1 161 MET 161 163 163 MET MET A . n A 1 162 PHE 162 164 164 PHE PHE A . n A 1 163 GLY 163 165 165 GLY GLY A . n A 1 164 PHE 164 166 166 PHE PHE A . n A 1 165 LEU 165 167 167 LEU LEU A . n A 1 166 ASP 166 168 168 ASP ASP A . n A 1 167 GLY 167 169 169 GLY GLY A . n A 1 168 ILE 168 170 170 ILE ILE A . n A 1 169 ALA 169 171 171 ALA ALA A . n A 1 170 GLN 170 172 172 GLN GLN A . n A 1 171 PRO 171 173 173 PRO PRO A . n A 1 172 ALA 172 174 174 ALA ALA A . n A 1 173 ILE 173 175 175 ILE ILE A . n A 1 174 ASN 174 176 176 ASN ASN A . n A 1 175 GLY 175 177 177 GLY GLY A . n A 1 176 PHE 176 178 178 PHE PHE A . n A 1 177 ASN 177 179 179 ASN ASN A . n A 1 178 THR 178 180 180 THR THR A . n A 1 179 PRO 179 181 181 PRO PRO A . n A 1 180 LEU 180 182 182 LEU LEU A . n A 1 181 PRO 181 183 183 PRO PRO A . n A 1 182 GLY 182 184 184 GLY GLY A . n A 1 183 GLN 183 185 185 GLN GLN A . n A 1 184 ASN 184 186 186 ASN ASN A . n A 1 185 ILE 185 187 187 ILE ILE A . n A 1 186 VAL 186 188 188 VAL VAL A . n A 1 187 ASP 187 189 189 ASP ASP A . n A 1 188 ALA 188 190 190 ALA ALA A . n A 1 189 GLY 189 191 191 GLY GLY A . n A 1 190 VAL 190 192 192 VAL VAL A . n A 1 191 ILE 191 193 193 ILE ILE A . n A 1 192 ILE 192 194 194 ILE ILE A . n A 1 193 THR 193 195 195 THR THR A . n A 1 194 GLY 194 196 196 GLY GLY A . n A 1 195 ALA 195 197 197 ALA ALA A . n A 1 196 THR 196 198 198 THR THR A . n A 1 197 ASN 197 199 199 ASN ASN A . n A 1 198 ASP 198 200 200 ASP ASP A . n A 1 199 PRO 199 201 201 PRO PRO A . n A 1 200 ILE 200 202 202 ILE ILE A . n A 1 201 THR 201 203 203 THR THR A . n A 1 202 ARG 202 204 204 ARG ARG A . n A 1 203 PRO 203 205 205 PRO PRO A . n A 1 204 SER 204 206 206 SER SER A . n A 1 205 TRP 205 207 207 TRP TRP A . n A 1 206 ALA 206 208 208 ALA ALA A . n A 1 207 VAL 207 209 209 VAL VAL A . n A 1 208 GLY 208 210 210 GLY GLY A . n A 1 209 GLY 209 211 211 GLY GLY A . n A 1 210 SER 210 212 212 SER SER A . n A 1 211 PHE 211 213 213 PHE PHE A . n A 1 212 LEU 212 214 214 LEU LEU A . n A 1 213 ALA 213 215 215 ALA ALA A . n A 1 214 PHE 214 216 216 PHE PHE A . n A 1 215 ARG 215 217 217 ARG ARG A . n A 1 216 GLN 216 218 218 GLN GLN A . n A 1 217 LEU 217 219 219 LEU LEU A . n A 1 218 GLU 218 220 220 GLU GLU A . n A 1 219 GLN 219 221 221 GLN GLN A . n A 1 220 LEU 220 222 222 LEU LEU A . n A 1 221 VAL 221 223 223 VAL VAL A . n A 1 222 PRO 222 224 224 PRO PRO A . n A 1 223 GLU 223 225 225 GLU GLU A . n A 1 224 PHE 224 226 226 PHE PHE A . n A 1 225 ASN 225 227 227 ASN ASN A . n A 1 226 LYS 226 228 228 LYS LYS A . n A 1 227 TYR 227 229 229 TYR TYR A . n A 1 228 LEU 228 230 230 LEU LEU A . n A 1 229 LEU 229 231 231 LEU LEU A . n A 1 230 ASP 230 232 232 ASP ASP A . n A 1 231 ASN 231 233 233 ASN ASN A . n A 1 232 ALA 232 234 234 ALA ALA A . n A 1 233 PRO 233 235 235 PRO PRO A . n A 1 234 ALA 234 236 236 ALA ALA A . n A 1 235 GLY 235 237 237 GLY GLY A . n A 1 236 SER 236 238 238 SER SER A . n A 1 237 GLY 237 239 239 GLY GLY A . n A 1 238 SER 238 240 240 SER SER A . n A 1 239 LEU 239 241 241 LEU LEU A . n A 1 240 GLN 240 242 242 GLN GLN A . n A 1 241 ALA 241 243 243 ALA ALA A . n A 1 242 ARG 242 244 244 ARG ARG A . n A 1 243 ALA 243 245 245 ALA ALA A . n A 1 244 ASP 244 246 246 ASP ASP A . n A 1 245 LEU 245 247 247 LEU LEU A . n A 1 246 LEU 246 248 248 LEU LEU A . n A 1 247 GLY 247 249 249 GLY GLY A . n A 1 248 ALA 248 250 250 ALA ALA A . n A 1 249 ARG 249 251 251 ARG ARG A . n A 1 250 MET 250 252 252 MET MET A . n A 1 251 VAL 251 253 253 VAL VAL A . n A 1 252 GLY 252 254 254 GLY GLY A . n A 1 253 ARG 253 255 255 ARG ARG A . n A 1 254 TRP 254 256 256 TRP TRP A . n A 1 255 LYS 255 257 257 LYS LYS A . n A 1 256 SER 256 258 258 SER SER A . n A 1 257 GLY 257 259 259 GLY GLY A . n A 1 258 ALA 258 260 260 ALA ALA A . n A 1 259 PRO 259 261 261 PRO PRO A . n A 1 260 ILE 260 262 262 ILE ILE A . n A 1 261 ASP 261 263 263 ASP ASP A . n A 1 262 LEU 262 264 264 LEU LEU A . n A 1 263 THR 263 265 265 THR THR A . n A 1 264 PRO 264 266 266 PRO PRO A . n A 1 265 THR 265 267 267 THR THR A . n A 1 266 ALA 266 268 268 ALA ALA A . n A 1 267 ASP 267 269 269 ASP ASP A . n A 1 268 ASP 268 270 270 ASP ASP A . n A 1 269 PRO 269 271 271 PRO PRO A . n A 1 270 ALA 270 272 272 ALA ALA A . n A 1 271 LEU 271 273 273 LEU LEU A . n A 1 272 GLY 272 274 274 GLY GLY A . n A 1 273 ALA 273 275 275 ALA ALA A . n A 1 274 ASP 274 276 276 ASP ASP A . n A 1 275 ALA 275 277 277 ALA ALA A . n A 1 276 GLN 276 278 278 GLN GLN A . n A 1 277 ARG 277 279 279 ARG ARG A . n A 1 278 ASN 278 280 280 ASN ASN A . n A 1 279 ASN 279 281 281 ASN ASN A . n A 1 280 ASN 280 282 282 ASN ASN A . n A 1 281 PHE 281 283 283 PHE PHE A . n A 1 282 THR 282 284 284 THR THR A . n A 1 283 TYR 283 285 285 TYR TYR A . n A 1 284 SER 284 286 286 SER SER A . n A 1 285 HIS 285 287 287 HIS HIS A . n A 1 286 ALA 286 288 288 ALA ALA A . n A 1 287 GLY 287 289 289 GLY GLY A . n A 1 288 PHE 288 290 290 PHE PHE A . n A 1 289 ASP 289 291 291 ASP ASP A . n A 1 290 LEU 290 292 292 LEU LEU A . n A 1 291 GLY 291 293 293 GLY GLY A . n A 1 292 SER 292 294 294 SER SER A . n A 1 293 ASP 293 295 295 ASP ASP A . n A 1 294 GLN 294 296 296 GLN GLN A . n A 1 295 SER 295 297 297 SER SER A . n A 1 296 HIS 296 298 298 HIS HIS A . n A 1 297 CYS 297 299 299 CYS CYS A . n A 1 298 PRO 298 300 300 PRO PRO A . n A 1 299 PHE 299 301 301 PHE PHE A . n A 1 300 SER 300 302 302 SER SER A . n A 1 301 ALA 301 303 303 ALA ALA A . n A 1 302 HIS 302 304 304 HIS HIS A . n A 1 303 ILE 303 305 305 ILE ILE A . n A 1 304 ARG 304 306 306 ARG ARG A . n A 1 305 LYS 305 307 307 LYS LYS A . n A 1 306 THR 306 308 308 THR THR A . n A 1 307 ARG 307 309 309 ARG ARG A . n A 1 308 PRO 308 310 310 PRO PRO A . n A 1 309 ARG 309 311 311 ARG ARG A . n A 1 310 ALA 310 312 312 ALA ALA A . n A 1 311 ASP 311 313 313 ASP ASP A . n A 1 312 LEU 312 314 314 LEU LEU A . n A 1 313 GLY 313 315 315 GLY GLY A . n A 1 314 GLY 314 316 316 GLY GLY A . n A 1 315 SER 315 317 317 SER SER A . n A 1 316 LEU 316 318 318 LEU LEU A . n A 1 317 THR 317 319 319 THR THR A . n A 1 318 PRO 318 320 320 PRO PRO A . n A 1 319 PRO 319 321 321 PRO PRO A . n A 1 320 ASN 320 322 322 ASN ASN A . n A 1 321 LEU 321 323 323 LEU LEU A . n A 1 322 SER 322 324 324 SER SER A . n A 1 323 ALA 323 325 325 ALA ALA A . n A 1 324 GLY 324 326 326 GLY GLY A . n A 1 325 ALA 325 327 327 ALA ALA A . n A 1 326 ASN 326 328 328 ASN ASN A . n A 1 327 SER 327 329 329 SER SER A . n A 1 328 ILE 328 330 330 ILE ILE A . n A 1 329 MET 329 331 331 MET MET A . n A 1 330 ARG 330 332 332 ARG ARG A . n A 1 331 SER 331 333 333 SER SER A . n A 1 332 GLY 332 334 334 GLY GLY A . n A 1 333 ILE 333 335 335 ILE ILE A . n A 1 334 PRO 334 336 336 PRO PRO A . n A 1 335 TYR 335 337 337 TYR TYR A . n A 1 336 GLY 336 338 338 GLY GLY A . n A 1 337 PRO 337 339 339 PRO PRO A . n A 1 338 GLU 338 340 340 GLU GLU A . n A 1 339 VAL 339 341 341 VAL VAL A . n A 1 340 THR 340 342 342 THR THR A . n A 1 341 SER 341 343 343 SER SER A . n A 1 342 ALA 342 344 344 ALA ALA A . n A 1 343 GLU 343 345 345 GLU GLU A . n A 1 344 SER 344 346 346 SER SER A . n A 1 345 ALA 345 347 347 ALA ALA A . n A 1 346 SER 346 348 348 SER SER A . n A 1 347 ASN 347 349 349 ASN ASN A . n A 1 348 THR 348 350 350 THR THR A . n A 1 349 THR 349 351 351 THR THR A . n A 1 350 THR 350 352 352 THR THR A . n A 1 351 GLN 351 353 353 GLN GLN A . n A 1 352 GLU 352 354 354 GLU GLU A . n A 1 353 ARG 353 355 355 ARG ARG A . n A 1 354 GLY 354 356 356 GLY GLY A . n A 1 355 LEU 355 357 357 LEU LEU A . n A 1 356 ALA 356 358 358 ALA ALA A . n A 1 357 PHE 357 359 359 PHE PHE A . n A 1 358 VAL 358 360 360 VAL VAL A . n A 1 359 ALA 359 361 361 ALA ALA A . n A 1 360 TYR 360 362 362 TYR TYR A . n A 1 361 GLN 361 363 363 GLN GLN A . n A 1 362 ALA 362 364 364 ALA ALA A . n A 1 363 GLN 363 365 365 GLN GLN A . n A 1 364 LEU 364 366 366 LEU LEU A . n A 1 365 SER 365 367 367 SER SER A . n A 1 366 GLN 366 368 368 GLN GLN A . n A 1 367 GLY 367 369 369 GLY GLY A . n A 1 368 PHE 368 370 370 PHE PHE A . n A 1 369 HIS 369 371 371 HIS HIS A . n A 1 370 PHE 370 372 372 PHE PHE A . n A 1 371 LEU 371 373 373 LEU LEU A . n A 1 372 GLN 372 374 374 GLN GLN A . n A 1 373 GLN 373 375 375 GLN GLN A . n A 1 374 THR 374 376 376 THR THR A . n A 1 375 TRP 375 377 377 TRP TRP A . n A 1 376 ALA 376 378 378 ALA ALA A . n A 1 377 ASP 377 379 379 ASP ASP A . n A 1 378 ASN 378 380 380 ASN ASN A . n A 1 379 ALA 379 381 381 ALA ALA A . n A 1 380 ASN 380 382 382 ASN ASN A . n A 1 381 PHE 381 383 383 PHE PHE A . n A 1 382 PRO 382 384 384 PRO PRO A . n A 1 383 PRO 383 385 385 PRO PRO A . n A 1 384 GLY 384 386 386 GLY GLY A . n A 1 385 LYS 385 387 387 LYS LYS A . n A 1 386 THR 386 388 388 THR THR A . n A 1 387 PRO 387 389 389 PRO PRO A . n A 1 388 ALA 388 390 390 ALA ALA A . n A 1 389 THR 389 391 391 THR THR A . n A 1 390 VAL 390 392 392 VAL VAL A . n A 1 391 GLY 391 393 393 GLY GLY A . n A 1 392 LEU 392 394 394 LEU LEU A . n A 1 393 ASP 393 395 395 ASP ASP A . n A 1 394 PRO 394 396 396 PRO PRO A . n A 1 395 ILE 395 397 397 ILE ILE A . n A 1 396 ILE 396 398 398 ILE ILE A . n A 1 397 GLY 397 399 399 GLY GLY A . n A 1 398 GLN 398 400 400 GLN GLN A . n A 1 399 ASN 399 401 401 ASN ASN A . n A 1 400 ASN 400 402 402 ASN ASN A . n A 1 401 GLY 401 403 403 GLY GLY A . n A 1 402 GLN 402 404 404 GLN GLN A . n A 1 403 PRO 403 405 405 PRO PRO A . n A 1 404 ARG 404 406 406 ARG ARG A . n A 1 405 VAL 405 407 407 VAL VAL A . n A 1 406 VAL 406 408 408 VAL VAL A . n A 1 407 ASN 407 409 409 ASN ASN A . n A 1 408 GLY 408 410 410 GLY GLY A . n A 1 409 LEU 409 411 411 LEU LEU A . n A 1 410 LEU 410 412 412 LEU LEU A . n A 1 411 PRO 411 413 413 PRO PRO A . n A 1 412 SER 412 414 414 SER SER A . n A 1 413 ASN 413 415 415 ASN ASN A . n A 1 414 SER 414 416 416 SER SER A . n A 1 415 SER 415 417 417 SER SER A . n A 1 416 ALA 416 418 418 ALA ALA A . n A 1 417 SER 417 419 419 SER SER A . n A 1 418 LEU 418 420 420 LEU LEU A . n A 1 419 SER 419 421 421 SER SER A . n A 1 420 ILE 420 422 422 ILE ILE A . n A 1 421 PRO 421 423 423 PRO PRO A . n A 1 422 GLN 422 424 424 GLN GLN A . n A 1 423 PHE 423 425 425 PHE PHE A . n A 1 424 VAL 424 426 426 VAL VAL A . n A 1 425 VAL 425 427 427 VAL VAL A . n A 1 426 SER 426 428 428 SER SER A . n A 1 427 HIS 427 429 429 HIS HIS A . n A 1 428 GLY 428 430 430 GLY GLY A . n A 1 429 GLY 429 431 431 GLY GLY A . n A 1 430 GLU 430 432 432 GLU GLU A . n A 1 431 TYR 431 433 433 TYR TYR A . n A 1 432 PHE 432 434 434 PHE PHE A . n A 1 433 PHE 433 435 435 PHE PHE A . n A 1 434 SER 434 436 436 SER SER A . n A 1 435 PRO 435 437 437 PRO PRO A . n A 1 436 PRO 436 438 438 PRO PRO A . n A 1 437 ILE 437 439 439 ILE ILE A . n A 1 438 SER 438 440 440 SER SER A . n A 1 439 ALA 439 441 441 ALA ALA A . n A 1 440 ILE 440 442 442 ILE ILE A . n A 1 441 GLY 441 443 443 GLY GLY A . n A 1 442 GLY 442 444 444 GLY GLY A . n A 1 443 ARG 443 445 445 ARG ARG A . n A 1 444 LEU 444 446 446 LEU LEU A . n A 1 445 SER 445 447 447 SER SER A . n A 1 446 ALA 446 448 448 ALA ALA A . n B 1 1 SER 1 3 ? ? ? B . n B 1 2 LEU 2 4 4 LEU LEU B . n B 1 3 ASN 3 5 5 ASN ASN B . n B 1 4 THR 4 6 6 THR THR B . n B 1 5 ASP 5 7 7 ASP ASP B . n B 1 6 ASP 6 8 8 ASP ASP B . n B 1 7 ILE 7 9 9 ILE ILE B . n B 1 8 GLN 8 10 10 GLN GLN B . n B 1 9 GLY 9 11 11 GLY GLY B . n B 1 10 ASP 10 12 12 ASP ASP B . n B 1 11 ILE 11 13 13 ILE ILE B . n B 1 12 LEU 12 14 14 LEU LEU B . n B 1 13 VAL 13 15 15 VAL VAL B . n B 1 14 GLY 14 16 16 GLY GLY B . n B 1 15 MET 15 17 17 MET MET B . n B 1 16 HIS 16 18 18 HIS HIS B . n B 1 17 LYS 17 19 19 LYS LYS B . n B 1 18 GLN 18 20 20 GLN GLN B . n B 1 19 LYS 19 21 21 LYS LYS B . n B 1 20 GLN 20 22 22 GLN GLN B . n B 1 21 LEU 21 23 23 LEU LEU B . n B 1 22 PHE 22 24 24 PHE PHE B . n B 1 23 TYR 23 25 25 TYR TYR B . n B 1 24 PHE 24 26 26 PHE PHE B . n B 1 25 PHE 25 27 27 PHE PHE B . n B 1 26 ALA 26 28 28 ALA ALA B . n B 1 27 ILE 27 29 29 ILE ILE B . n B 1 28 ASN 28 30 30 ASN ASN B . n B 1 29 ASP 29 31 31 ASP ASP B . n B 1 30 PRO 30 32 32 PRO PRO B . n B 1 31 ALA 31 33 33 ALA ALA B . n B 1 32 THR 32 34 34 THR THR B . n B 1 33 PHE 33 35 35 PHE PHE B . n B 1 34 LYS 34 36 36 LYS LYS B . n B 1 35 THR 35 37 37 THR THR B . n B 1 36 HIS 36 38 38 HIS HIS B . n B 1 37 LEU 37 39 39 LEU LEU B . n B 1 38 ALA 38 40 40 ALA ALA B . n B 1 39 SER 39 41 41 SER SER B . n B 1 40 ASP 40 42 42 ASP ASP B . n B 1 41 ILE 41 43 43 ILE ILE B . n B 1 42 ALA 42 44 44 ALA ALA B . n B 1 43 PRO 43 45 45 PRO PRO B . n B 1 44 VAL 44 46 46 VAL VAL B . n B 1 45 VAL 45 47 47 VAL VAL B . n B 1 46 ALA 46 48 48 ALA ALA B . n B 1 47 SER 47 49 49 SER SER B . n B 1 48 VAL 48 50 50 VAL VAL B . n B 1 49 THR 49 51 51 THR THR B . n B 1 50 GLN 50 52 52 GLN GLN B . n B 1 51 LEU 51 53 53 LEU LEU B . n B 1 52 SER 52 54 54 SER SER B . n B 1 53 ASN 53 55 55 ASN ASN B . n B 1 54 VAL 54 56 56 VAL VAL B . n B 1 55 ALA 55 57 57 ALA ALA B . n B 1 56 THR 56 58 58 THR THR B . n B 1 57 GLN 57 59 59 GLN GLN B . n B 1 58 PRO 58 60 60 PRO PRO B . n B 1 59 LEU 59 61 61 LEU LEU B . n B 1 60 VAL 60 62 62 VAL VAL B . n B 1 61 ALA 61 63 63 ALA ALA B . n B 1 62 LEU 62 64 64 LEU LEU B . n B 1 63 ASN 63 65 65 ASN ASN B . n B 1 64 ILE 64 66 66 ILE ILE B . n B 1 65 ALA 65 67 67 ALA ALA B . n B 1 66 PHE 66 68 68 PHE PHE B . n B 1 67 SER 67 69 69 SER SER B . n B 1 68 ASN 68 70 70 ASN ASN B . n B 1 69 THR 69 71 71 THR THR B . n B 1 70 GLY 70 72 72 GLY GLY B . n B 1 71 LEU 71 73 73 LEU LEU B . n B 1 72 LEU 72 74 74 LEU LEU B . n B 1 73 ALA 73 75 75 ALA ALA B . n B 1 74 LEU 74 76 76 LEU LEU B . n B 1 75 GLY 75 77 77 GLY GLY B . n B 1 76 VAL 76 78 78 VAL VAL B . n B 1 77 THR 77 79 79 THR THR B . n B 1 78 ASP 78 80 80 ASP ASP B . n B 1 79 ASN 79 81 81 ASN ASN B . n B 1 80 LEU 80 82 82 LEU LEU B . n B 1 81 GLY 81 83 83 GLY GLY B . n B 1 82 ASP 82 84 84 ASP ASP B . n B 1 83 SER 83 85 85 SER SER B . n B 1 84 LEU 84 86 86 LEU LEU B . n B 1 85 PHE 85 87 87 PHE PHE B . n B 1 86 ALA 86 88 88 ALA ALA B . n B 1 87 ASN 87 89 89 ASN ASN B . n B 1 88 GLY 88 90 90 GLY GLY B . n B 1 89 GLN 89 91 91 GLN GLN B . n B 1 90 ALA 90 92 92 ALA ALA B . n B 1 91 LYS 91 93 93 LYS LYS B . n B 1 92 ASP 92 94 94 ASP ASP B . n B 1 93 ALA 93 95 95 ALA ALA B . n B 1 94 THR 94 96 96 THR THR B . n B 1 95 SER 95 97 97 SER SER B . n B 1 96 PHE 96 98 98 PHE PHE B . n B 1 97 LYS 97 99 99 LYS LYS B . n B 1 98 GLU 98 100 100 GLU GLU B . n B 1 99 SER 99 101 101 SER SER B . n B 1 100 THR 100 102 102 THR THR B . n B 1 101 SER 101 103 103 SER SER B . n B 1 102 SER 102 104 104 SER SER B . n B 1 103 TRP 103 105 105 TRP TRP B . n B 1 104 VAL 104 106 106 VAL VAL B . n B 1 105 PRO 105 107 107 PRO PRO B . n B 1 106 GLN 106 108 108 GLN GLN B . n B 1 107 PHE 107 109 109 PHE PHE B . n B 1 108 ALA 108 110 110 ALA ALA B . n B 1 109 GLY 109 111 111 GLY GLY B . n B 1 110 THR 110 112 112 THR THR B . n B 1 111 GLY 111 113 113 GLY GLY B . n B 1 112 ILE 112 114 114 ILE ILE B . n B 1 113 HIS 113 115 115 HIS HIS B . n B 1 114 GLY 114 116 116 GLY GLY B . n B 1 115 VAL 115 117 117 VAL VAL B . n B 1 116 ILE 116 118 118 ILE ILE B . n B 1 117 ILE 117 119 119 ILE ILE B . n B 1 118 LEU 118 120 120 LEU LEU B . n B 1 119 ALA 119 121 121 ALA ALA B . n B 1 120 SER 120 122 122 SER SER B . n B 1 121 ASP 121 123 123 ASP ASP B . n B 1 122 THR 122 124 124 THR THR B . n B 1 123 THR 123 125 125 THR THR B . n B 1 124 ASP 124 126 126 ASP ASP B . n B 1 125 LEU 125 127 127 LEU LEU B . n B 1 126 ILE 126 128 128 ILE ILE B . n B 1 127 ASP 127 129 129 ASP ASP B . n B 1 128 GLN 128 130 130 GLN GLN B . n B 1 129 GLN 129 131 131 GLN GLN B . n B 1 130 VAL 130 132 132 VAL VAL B . n B 1 131 ALA 131 133 133 ALA ALA B . n B 1 132 SER 132 134 134 SER SER B . n B 1 133 ILE 133 135 135 ILE ILE B . n B 1 134 GLU 134 136 136 GLU GLU B . n B 1 135 SER 135 137 137 SER SER B . n B 1 136 THR 136 138 138 THR THR B . n B 1 137 PHE 137 139 139 PHE PHE B . n B 1 138 GLY 138 140 140 GLY GLY B . n B 1 139 SER 139 141 141 SER SER B . n B 1 140 SER 140 142 142 SER SER B . n B 1 141 ILE 141 143 143 ILE ILE B . n B 1 142 SER 142 144 144 SER SER B . n B 1 143 LYS 143 145 145 LYS LYS B . n B 1 144 LEU 144 146 146 LEU LEU B . n B 1 145 TYR 145 147 147 TYR TYR B . n B 1 146 SER 146 148 148 SER SER B . n B 1 147 LEU 147 149 149 LEU LEU B . n B 1 148 SER 148 150 150 SER SER B . n B 1 149 ALA 149 151 151 ALA ALA B . n B 1 150 SER 150 152 152 SER SER B . n B 1 151 ILE 151 153 153 ILE ILE B . n B 1 152 ARG 152 154 154 ARG ARG B . n B 1 153 PRO 153 155 155 PRO PRO B . n B 1 154 GLY 154 156 156 GLY GLY B . n B 1 155 ASN 155 157 157 ASN ASN B . n B 1 156 GLU 156 158 158 GLU GLU B . n B 1 157 ALA 157 159 159 ALA ALA B . n B 1 158 GLY 158 160 160 GLY GLY B . n B 1 159 HIS 159 161 161 HIS HIS B . n B 1 160 GLU 160 162 162 GLU GLU B . n B 1 161 MET 161 163 163 MET MET B . n B 1 162 PHE 162 164 164 PHE PHE B . n B 1 163 GLY 163 165 165 GLY GLY B . n B 1 164 PHE 164 166 166 PHE PHE B . n B 1 165 LEU 165 167 167 LEU LEU B . n B 1 166 ASP 166 168 168 ASP ASP B . n B 1 167 GLY 167 169 169 GLY GLY B . n B 1 168 ILE 168 170 170 ILE ILE B . n B 1 169 ALA 169 171 171 ALA ALA B . n B 1 170 GLN 170 172 172 GLN GLN B . n B 1 171 PRO 171 173 173 PRO PRO B . n B 1 172 ALA 172 174 174 ALA ALA B . n B 1 173 ILE 173 175 175 ILE ILE B . n B 1 174 ASN 174 176 176 ASN ASN B . n B 1 175 GLY 175 177 177 GLY GLY B . n B 1 176 PHE 176 178 178 PHE PHE B . n B 1 177 ASN 177 179 179 ASN ASN B . n B 1 178 THR 178 180 180 THR THR B . n B 1 179 PRO 179 181 181 PRO PRO B . n B 1 180 LEU 180 182 182 LEU LEU B . n B 1 181 PRO 181 183 183 PRO PRO B . n B 1 182 GLY 182 184 184 GLY GLY B . n B 1 183 GLN 183 185 185 GLN GLN B . n B 1 184 ASN 184 186 186 ASN ASN B . n B 1 185 ILE 185 187 187 ILE ILE B . n B 1 186 VAL 186 188 188 VAL VAL B . n B 1 187 ASP 187 189 189 ASP ASP B . n B 1 188 ALA 188 190 190 ALA ALA B . n B 1 189 GLY 189 191 191 GLY GLY B . n B 1 190 VAL 190 192 192 VAL VAL B . n B 1 191 ILE 191 193 193 ILE ILE B . n B 1 192 ILE 192 194 194 ILE ILE B . n B 1 193 THR 193 195 195 THR THR B . n B 1 194 GLY 194 196 196 GLY GLY B . n B 1 195 ALA 195 197 197 ALA ALA B . n B 1 196 THR 196 198 198 THR THR B . n B 1 197 ASN 197 199 199 ASN ASN B . n B 1 198 ASP 198 200 200 ASP ASP B . n B 1 199 PRO 199 201 201 PRO PRO B . n B 1 200 ILE 200 202 202 ILE ILE B . n B 1 201 THR 201 203 203 THR THR B . n B 1 202 ARG 202 204 204 ARG ARG B . n B 1 203 PRO 203 205 205 PRO PRO B . n B 1 204 SER 204 206 206 SER SER B . n B 1 205 TRP 205 207 207 TRP TRP B . n B 1 206 ALA 206 208 208 ALA ALA B . n B 1 207 VAL 207 209 209 VAL VAL B . n B 1 208 GLY 208 210 210 GLY GLY B . n B 1 209 GLY 209 211 211 GLY GLY B . n B 1 210 SER 210 212 212 SER SER B . n B 1 211 PHE 211 213 213 PHE PHE B . n B 1 212 LEU 212 214 214 LEU LEU B . n B 1 213 ALA 213 215 215 ALA ALA B . n B 1 214 PHE 214 216 216 PHE PHE B . n B 1 215 ARG 215 217 217 ARG ARG B . n B 1 216 GLN 216 218 218 GLN GLN B . n B 1 217 LEU 217 219 219 LEU LEU B . n B 1 218 GLU 218 220 220 GLU GLU B . n B 1 219 GLN 219 221 221 GLN GLN B . n B 1 220 LEU 220 222 222 LEU LEU B . n B 1 221 VAL 221 223 223 VAL VAL B . n B 1 222 PRO 222 224 224 PRO PRO B . n B 1 223 GLU 223 225 225 GLU GLU B . n B 1 224 PHE 224 226 226 PHE PHE B . n B 1 225 ASN 225 227 227 ASN ASN B . n B 1 226 LYS 226 228 228 LYS LYS B . n B 1 227 TYR 227 229 229 TYR TYR B . n B 1 228 LEU 228 230 230 LEU LEU B . n B 1 229 LEU 229 231 231 LEU LEU B . n B 1 230 ASP 230 232 232 ASP ASP B . n B 1 231 ASN 231 233 233 ASN ASN B . n B 1 232 ALA 232 234 234 ALA ALA B . n B 1 233 PRO 233 235 235 PRO PRO B . n B 1 234 ALA 234 236 236 ALA ALA B . n B 1 235 GLY 235 237 237 GLY GLY B . n B 1 236 SER 236 238 238 SER SER B . n B 1 237 GLY 237 239 239 GLY GLY B . n B 1 238 SER 238 240 240 SER SER B . n B 1 239 LEU 239 241 241 LEU LEU B . n B 1 240 GLN 240 242 242 GLN GLN B . n B 1 241 ALA 241 243 243 ALA ALA B . n B 1 242 ARG 242 244 244 ARG ARG B . n B 1 243 ALA 243 245 245 ALA ALA B . n B 1 244 ASP 244 246 246 ASP ASP B . n B 1 245 LEU 245 247 247 LEU LEU B . n B 1 246 LEU 246 248 248 LEU LEU B . n B 1 247 GLY 247 249 249 GLY GLY B . n B 1 248 ALA 248 250 250 ALA ALA B . n B 1 249 ARG 249 251 251 ARG ARG B . n B 1 250 MET 250 252 252 MET MET B . n B 1 251 VAL 251 253 253 VAL VAL B . n B 1 252 GLY 252 254 254 GLY GLY B . n B 1 253 ARG 253 255 255 ARG ARG B . n B 1 254 TRP 254 256 256 TRP TRP B . n B 1 255 LYS 255 257 257 LYS LYS B . n B 1 256 SER 256 258 258 SER SER B . n B 1 257 GLY 257 259 259 GLY GLY B . n B 1 258 ALA 258 260 260 ALA ALA B . n B 1 259 PRO 259 261 261 PRO PRO B . n B 1 260 ILE 260 262 262 ILE ILE B . n B 1 261 ASP 261 263 263 ASP ASP B . n B 1 262 LEU 262 264 264 LEU LEU B . n B 1 263 THR 263 265 265 THR THR B . n B 1 264 PRO 264 266 266 PRO PRO B . n B 1 265 THR 265 267 267 THR THR B . n B 1 266 ALA 266 268 268 ALA ALA B . n B 1 267 ASP 267 269 269 ASP ASP B . n B 1 268 ASP 268 270 270 ASP ASP B . n B 1 269 PRO 269 271 271 PRO PRO B . n B 1 270 ALA 270 272 272 ALA ALA B . n B 1 271 LEU 271 273 273 LEU LEU B . n B 1 272 GLY 272 274 274 GLY GLY B . n B 1 273 ALA 273 275 275 ALA ALA B . n B 1 274 ASP 274 276 276 ASP ASP B . n B 1 275 ALA 275 277 277 ALA ALA B . n B 1 276 GLN 276 278 278 GLN GLN B . n B 1 277 ARG 277 279 279 ARG ARG B . n B 1 278 ASN 278 280 280 ASN ASN B . n B 1 279 ASN 279 281 281 ASN ASN B . n B 1 280 ASN 280 282 282 ASN ASN B . n B 1 281 PHE 281 283 283 PHE PHE B . n B 1 282 THR 282 284 284 THR THR B . n B 1 283 TYR 283 285 285 TYR TYR B . n B 1 284 SER 284 286 286 SER SER B . n B 1 285 HIS 285 287 287 HIS HIS B . n B 1 286 ALA 286 288 288 ALA ALA B . n B 1 287 GLY 287 289 289 GLY GLY B . n B 1 288 PHE 288 290 290 PHE PHE B . n B 1 289 ASP 289 291 291 ASP ASP B . n B 1 290 LEU 290 292 292 LEU LEU B . n B 1 291 GLY 291 293 293 GLY GLY B . n B 1 292 SER 292 294 294 SER SER B . n B 1 293 ASP 293 295 295 ASP ASP B . n B 1 294 GLN 294 296 296 GLN GLN B . n B 1 295 SER 295 297 297 SER SER B . n B 1 296 HIS 296 298 298 HIS HIS B . n B 1 297 CYS 297 299 299 CYS CYS B . n B 1 298 PRO 298 300 300 PRO PRO B . n B 1 299 PHE 299 301 301 PHE PHE B . n B 1 300 SER 300 302 302 SER SER B . n B 1 301 ALA 301 303 303 ALA ALA B . n B 1 302 HIS 302 304 304 HIS HIS B . n B 1 303 ILE 303 305 305 ILE ILE B . n B 1 304 ARG 304 306 306 ARG ARG B . n B 1 305 LYS 305 307 307 LYS LYS B . n B 1 306 THR 306 308 308 THR THR B . n B 1 307 ARG 307 309 309 ARG ARG B . n B 1 308 PRO 308 310 310 PRO PRO B . n B 1 309 ARG 309 311 311 ARG ARG B . n B 1 310 ALA 310 312 312 ALA ALA B . n B 1 311 ASP 311 313 313 ASP ASP B . n B 1 312 LEU 312 314 314 LEU LEU B . n B 1 313 GLY 313 315 315 GLY GLY B . n B 1 314 GLY 314 316 316 GLY GLY B . n B 1 315 SER 315 317 317 SER SER B . n B 1 316 LEU 316 318 318 LEU LEU B . n B 1 317 THR 317 319 319 THR THR B . n B 1 318 PRO 318 320 320 PRO PRO B . n B 1 319 PRO 319 321 321 PRO PRO B . n B 1 320 ASN 320 322 322 ASN ASN B . n B 1 321 LEU 321 323 323 LEU LEU B . n B 1 322 SER 322 324 324 SER SER B . n B 1 323 ALA 323 325 325 ALA ALA B . n B 1 324 GLY 324 326 326 GLY GLY B . n B 1 325 ALA 325 327 327 ALA ALA B . n B 1 326 ASN 326 328 328 ASN ASN B . n B 1 327 SER 327 329 329 SER SER B . n B 1 328 ILE 328 330 330 ILE ILE B . n B 1 329 MET 329 331 331 MET MET B . n B 1 330 ARG 330 332 332 ARG ARG B . n B 1 331 SER 331 333 333 SER SER B . n B 1 332 GLY 332 334 334 GLY GLY B . n B 1 333 ILE 333 335 335 ILE ILE B . n B 1 334 PRO 334 336 336 PRO PRO B . n B 1 335 TYR 335 337 337 TYR TYR B . n B 1 336 GLY 336 338 338 GLY GLY B . n B 1 337 PRO 337 339 339 PRO PRO B . n B 1 338 GLU 338 340 340 GLU GLU B . n B 1 339 VAL 339 341 341 VAL VAL B . n B 1 340 THR 340 342 342 THR THR B . n B 1 341 SER 341 343 343 SER SER B . n B 1 342 ALA 342 344 344 ALA ALA B . n B 1 343 GLU 343 345 345 GLU GLU B . n B 1 344 SER 344 346 346 SER SER B . n B 1 345 ALA 345 347 347 ALA ALA B . n B 1 346 SER 346 348 348 SER SER B . n B 1 347 ASN 347 349 349 ASN ASN B . n B 1 348 THR 348 350 350 THR THR B . n B 1 349 THR 349 351 351 THR THR B . n B 1 350 THR 350 352 352 THR THR B . n B 1 351 GLN 351 353 353 GLN GLN B . n B 1 352 GLU 352 354 354 GLU GLU B . n B 1 353 ARG 353 355 355 ARG ARG B . n B 1 354 GLY 354 356 356 GLY GLY B . n B 1 355 LEU 355 357 357 LEU LEU B . n B 1 356 ALA 356 358 358 ALA ALA B . n B 1 357 PHE 357 359 359 PHE PHE B . n B 1 358 VAL 358 360 360 VAL VAL B . n B 1 359 ALA 359 361 361 ALA ALA B . n B 1 360 TYR 360 362 362 TYR TYR B . n B 1 361 GLN 361 363 363 GLN GLN B . n B 1 362 ALA 362 364 364 ALA ALA B . n B 1 363 GLN 363 365 365 GLN GLN B . n B 1 364 LEU 364 366 366 LEU LEU B . n B 1 365 SER 365 367 367 SER SER B . n B 1 366 GLN 366 368 368 GLN GLN B . n B 1 367 GLY 367 369 369 GLY GLY B . n B 1 368 PHE 368 370 370 PHE PHE B . n B 1 369 HIS 369 371 371 HIS HIS B . n B 1 370 PHE 370 372 372 PHE PHE B . n B 1 371 LEU 371 373 373 LEU LEU B . n B 1 372 GLN 372 374 374 GLN GLN B . n B 1 373 GLN 373 375 375 GLN GLN B . n B 1 374 THR 374 376 376 THR THR B . n B 1 375 TRP 375 377 377 TRP TRP B . n B 1 376 ALA 376 378 378 ALA ALA B . n B 1 377 ASP 377 379 379 ASP ASP B . n B 1 378 ASN 378 380 380 ASN ASN B . n B 1 379 ALA 379 381 381 ALA ALA B . n B 1 380 ASN 380 382 382 ASN ASN B . n B 1 381 PHE 381 383 383 PHE PHE B . n B 1 382 PRO 382 384 384 PRO PRO B . n B 1 383 PRO 383 385 385 PRO PRO B . n B 1 384 GLY 384 386 386 GLY GLY B . n B 1 385 LYS 385 387 387 LYS LYS B . n B 1 386 THR 386 388 388 THR THR B . n B 1 387 PRO 387 389 389 PRO PRO B . n B 1 388 ALA 388 390 390 ALA ALA B . n B 1 389 THR 389 391 391 THR THR B . n B 1 390 VAL 390 392 392 VAL VAL B . n B 1 391 GLY 391 393 393 GLY GLY B . n B 1 392 LEU 392 394 394 LEU LEU B . n B 1 393 ASP 393 395 395 ASP ASP B . n B 1 394 PRO 394 396 396 PRO PRO B . n B 1 395 ILE 395 397 397 ILE ILE B . n B 1 396 ILE 396 398 398 ILE ILE B . n B 1 397 GLY 397 399 399 GLY GLY B . n B 1 398 GLN 398 400 400 GLN GLN B . n B 1 399 ASN 399 401 401 ASN ASN B . n B 1 400 ASN 400 402 402 ASN ASN B . n B 1 401 GLY 401 403 403 GLY GLY B . n B 1 402 GLN 402 404 404 GLN GLN B . n B 1 403 PRO 403 405 405 PRO PRO B . n B 1 404 ARG 404 406 406 ARG ARG B . n B 1 405 VAL 405 407 407 VAL VAL B . n B 1 406 VAL 406 408 408 VAL VAL B . n B 1 407 ASN 407 409 409 ASN ASN B . n B 1 408 GLY 408 410 410 GLY GLY B . n B 1 409 LEU 409 411 411 LEU LEU B . n B 1 410 LEU 410 412 412 LEU LEU B . n B 1 411 PRO 411 413 413 PRO PRO B . n B 1 412 SER 412 414 414 SER SER B . n B 1 413 ASN 413 415 415 ASN ASN B . n B 1 414 SER 414 416 416 SER SER B . n B 1 415 SER 415 417 417 SER SER B . n B 1 416 ALA 416 418 418 ALA ALA B . n B 1 417 SER 417 419 419 SER SER B . n B 1 418 LEU 418 420 420 LEU LEU B . n B 1 419 SER 419 421 421 SER SER B . n B 1 420 ILE 420 422 422 ILE ILE B . n B 1 421 PRO 421 423 423 PRO PRO B . n B 1 422 GLN 422 424 424 GLN GLN B . n B 1 423 PHE 423 425 425 PHE PHE B . n B 1 424 VAL 424 426 426 VAL VAL B . n B 1 425 VAL 425 427 427 VAL VAL B . n B 1 426 SER 426 428 428 SER SER B . n B 1 427 HIS 427 429 429 HIS HIS B . n B 1 428 GLY 428 430 430 GLY GLY B . n B 1 429 GLY 429 431 431 GLY GLY B . n B 1 430 GLU 430 432 432 GLU GLU B . n B 1 431 TYR 431 433 433 TYR TYR B . n B 1 432 PHE 432 434 434 PHE PHE B . n B 1 433 PHE 433 435 435 PHE PHE B . n B 1 434 SER 434 436 436 SER SER B . n B 1 435 PRO 435 437 437 PRO PRO B . n B 1 436 PRO 436 438 438 PRO PRO B . n B 1 437 ILE 437 439 439 ILE ILE B . n B 1 438 SER 438 440 440 SER SER B . n B 1 439 ALA 439 441 441 ALA ALA B . n B 1 440 ILE 440 442 442 ILE ILE B . n B 1 441 GLY 441 443 443 GLY GLY B . n B 1 442 GLY 442 444 444 GLY GLY B . n B 1 443 ARG 443 445 445 ARG ARG B . n B 1 444 LEU 444 446 446 LEU LEU B . n B 1 445 SER 445 447 447 SER SER B . n B 1 446 ALA 446 448 448 ALA ALA B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 CAC 1 1449 1449 CAC CAC A . D 3 GOL 1 1450 1450 GOL GOL A . E 3 GOL 1 1451 1451 GOL GOL A . F 3 GOL 1 1452 1452 GOL GOL A . G 3 GOL 1 1453 1453 GOL GOL A . H 4 NAG 1 1454 1454 NAG NAG A . I 4 NAG 2 1457 1457 NAG NAG A . J 4 NAG 1 1455 1455 NAG NAG A . K 4 NAG 1 1456 1456 NAG NAG A . L 5 N7H 1 1458 1458 N7H N7H A . M 6 FMT 1 1459 1459 FMT FMT A . N 7 NO2 1 1460 1460 NO2 NO2 A . O 2 CAC 1 1449 1449 CAC CAC B . P 3 GOL 1 1450 1450 GOL GOL B . Q 3 GOL 1 1451 1451 GOL GOL B . R 3 GOL 1 1452 1452 GOL GOL B . S 3 GOL 1 1453 1453 GOL GOL B . T 4 NAG 1 1454 1454 NAG NAG B . U 4 NAG 1 1455 1455 NAG NAG B . V 5 N7H 1 1456 1456 N7H N7H B . W 7 NO2 1 1457 1457 NO2 NO2 B . X 8 HOH 1 2001 2001 HOH HOH A . X 8 HOH 2 2002 2002 HOH HOH A . X 8 HOH 3 2003 2003 HOH HOH A . X 8 HOH 4 2004 2004 HOH HOH A . X 8 HOH 5 2005 2005 HOH HOH A . X 8 HOH 6 2006 2006 HOH HOH A . X 8 HOH 7 2007 2007 HOH HOH A . X 8 HOH 8 2008 2008 HOH HOH A . X 8 HOH 9 2009 2009 HOH HOH A . X 8 HOH 10 2010 2010 HOH HOH A . X 8 HOH 11 2011 2011 HOH HOH A . X 8 HOH 12 2012 2012 HOH HOH A . X 8 HOH 13 2013 2013 HOH HOH A . X 8 HOH 14 2014 2014 HOH HOH A . X 8 HOH 15 2015 2015 HOH HOH A . X 8 HOH 16 2016 2016 HOH HOH A . X 8 HOH 17 2017 2017 HOH HOH A . X 8 HOH 18 2018 2018 HOH HOH A . X 8 HOH 19 2019 2019 HOH HOH A . X 8 HOH 20 2020 2020 HOH HOH A . X 8 HOH 21 2021 2021 HOH HOH A . X 8 HOH 22 2022 2022 HOH HOH A . X 8 HOH 23 2023 2023 HOH HOH A . X 8 HOH 24 2024 2024 HOH HOH A . X 8 HOH 25 2025 2025 HOH HOH A . X 8 HOH 26 2026 2026 HOH HOH A . X 8 HOH 27 2027 2027 HOH HOH A . X 8 HOH 28 2028 2028 HOH HOH A . X 8 HOH 29 2029 2029 HOH HOH A . X 8 HOH 30 2030 2030 HOH HOH A . X 8 HOH 31 2031 2031 HOH HOH A . X 8 HOH 32 2032 2032 HOH HOH A . X 8 HOH 33 2033 2033 HOH HOH A . X 8 HOH 34 2034 2034 HOH HOH A . X 8 HOH 35 2035 2035 HOH HOH A . X 8 HOH 36 2036 2036 HOH HOH A . X 8 HOH 37 2037 2037 HOH HOH A . X 8 HOH 38 2038 2038 HOH HOH A . X 8 HOH 39 2039 2039 HOH HOH A . X 8 HOH 40 2040 2040 HOH HOH A . X 8 HOH 41 2041 2041 HOH HOH A . X 8 HOH 42 2042 2042 HOH HOH A . X 8 HOH 43 2043 2043 HOH HOH A . X 8 HOH 44 2044 2044 HOH HOH A . X 8 HOH 45 2045 2045 HOH HOH A . X 8 HOH 46 2046 2046 HOH HOH A . X 8 HOH 47 2047 2047 HOH HOH A . X 8 HOH 48 2048 2048 HOH HOH A . X 8 HOH 49 2049 2049 HOH HOH A . X 8 HOH 50 2050 2050 HOH HOH A . X 8 HOH 51 2051 2051 HOH HOH A . X 8 HOH 52 2052 2052 HOH HOH A . X 8 HOH 53 2053 2053 HOH HOH A . X 8 HOH 54 2054 2054 HOH HOH A . X 8 HOH 55 2055 2055 HOH HOH A . X 8 HOH 56 2056 2056 HOH HOH A . X 8 HOH 57 2057 2057 HOH HOH A . X 8 HOH 58 2058 2058 HOH HOH A . X 8 HOH 59 2059 2059 HOH HOH A . X 8 HOH 60 2060 2060 HOH HOH A . X 8 HOH 61 2061 2061 HOH HOH A . X 8 HOH 62 2062 2062 HOH HOH A . X 8 HOH 63 2063 2063 HOH HOH A . X 8 HOH 64 2064 2064 HOH HOH A . X 8 HOH 65 2065 2065 HOH HOH A . X 8 HOH 66 2066 2066 HOH HOH A . X 8 HOH 67 2067 2067 HOH HOH A . X 8 HOH 68 2068 2068 HOH HOH A . X 8 HOH 69 2069 2069 HOH HOH A . X 8 HOH 70 2070 2070 HOH HOH A . X 8 HOH 71 2071 2071 HOH HOH A . X 8 HOH 72 2072 2072 HOH HOH A . X 8 HOH 73 2073 2073 HOH HOH A . X 8 HOH 74 2074 2074 HOH HOH A . X 8 HOH 75 2075 2075 HOH HOH A . X 8 HOH 76 2076 2076 HOH HOH A . X 8 HOH 77 2077 2077 HOH HOH A . X 8 HOH 78 2078 2078 HOH HOH A . X 8 HOH 79 2079 2079 HOH HOH A . X 8 HOH 80 2080 2080 HOH HOH A . X 8 HOH 81 2081 2081 HOH HOH A . X 8 HOH 82 2082 2082 HOH HOH A . X 8 HOH 83 2083 2083 HOH HOH A . X 8 HOH 84 2084 2084 HOH HOH A . X 8 HOH 85 2085 2085 HOH HOH A . X 8 HOH 86 2086 2086 HOH HOH A . X 8 HOH 87 2087 2087 HOH HOH A . X 8 HOH 88 2088 2088 HOH HOH A . X 8 HOH 89 2089 2089 HOH HOH A . X 8 HOH 90 2090 2090 HOH HOH A . X 8 HOH 91 2091 2091 HOH HOH A . X 8 HOH 92 2092 2092 HOH HOH A . X 8 HOH 93 2093 2093 HOH HOH A . X 8 HOH 94 2094 2094 HOH HOH A . X 8 HOH 95 2095 2095 HOH HOH A . X 8 HOH 96 2096 2096 HOH HOH A . X 8 HOH 97 2097 2097 HOH HOH A . X 8 HOH 98 2098 2098 HOH HOH A . X 8 HOH 99 2099 2099 HOH HOH A . X 8 HOH 100 2100 2100 HOH HOH A . X 8 HOH 101 2101 2101 HOH HOH A . X 8 HOH 102 2102 2102 HOH HOH A . X 8 HOH 103 2103 2103 HOH HOH A . X 8 HOH 104 2104 2104 HOH HOH A . X 8 HOH 105 2105 2105 HOH HOH A . X 8 HOH 106 2106 2106 HOH HOH A . X 8 HOH 107 2107 2107 HOH HOH A . X 8 HOH 108 2108 2108 HOH HOH A . X 8 HOH 109 2109 2109 HOH HOH A . X 8 HOH 110 2110 2110 HOH HOH A . X 8 HOH 111 2111 2111 HOH HOH A . X 8 HOH 112 2112 2112 HOH HOH A . X 8 HOH 113 2113 2113 HOH HOH A . X 8 HOH 114 2114 2114 HOH HOH A . X 8 HOH 115 2115 2115 HOH HOH A . X 8 HOH 116 2116 2116 HOH HOH A . X 8 HOH 117 2117 2117 HOH HOH A . X 8 HOH 118 2118 2118 HOH HOH A . X 8 HOH 119 2119 2119 HOH HOH A . X 8 HOH 120 2120 2120 HOH HOH A . X 8 HOH 121 2121 2121 HOH HOH A . X 8 HOH 122 2122 2122 HOH HOH A . X 8 HOH 123 2123 2123 HOH HOH A . X 8 HOH 124 2124 2124 HOH HOH A . X 8 HOH 125 2125 2125 HOH HOH A . X 8 HOH 126 2126 2126 HOH HOH A . X 8 HOH 127 2127 2127 HOH HOH A . X 8 HOH 128 2128 2128 HOH HOH A . X 8 HOH 129 2129 2129 HOH HOH A . X 8 HOH 130 2130 2130 HOH HOH A . X 8 HOH 131 2131 2131 HOH HOH A . X 8 HOH 132 2132 2132 HOH HOH A . X 8 HOH 133 2133 2133 HOH HOH A . X 8 HOH 134 2134 2134 HOH HOH A . X 8 HOH 135 2135 2135 HOH HOH A . X 8 HOH 136 2136 2136 HOH HOH A . X 8 HOH 137 2137 2137 HOH HOH A . X 8 HOH 138 2138 2138 HOH HOH A . X 8 HOH 139 2139 2139 HOH HOH A . X 8 HOH 140 2140 2140 HOH HOH A . X 8 HOH 141 2141 2141 HOH HOH A . X 8 HOH 142 2142 2142 HOH HOH A . X 8 HOH 143 2143 2143 HOH HOH A . X 8 HOH 144 2144 2144 HOH HOH A . X 8 HOH 145 2145 2145 HOH HOH A . X 8 HOH 146 2146 2146 HOH HOH A . X 8 HOH 147 2147 2147 HOH HOH A . X 8 HOH 148 2148 2148 HOH HOH A . X 8 HOH 149 2149 2149 HOH HOH A . X 8 HOH 150 2150 2150 HOH HOH A . X 8 HOH 151 2151 2151 HOH HOH A . X 8 HOH 152 2152 2152 HOH HOH A . X 8 HOH 153 2153 2153 HOH HOH A . X 8 HOH 154 2154 2154 HOH HOH A . X 8 HOH 155 2155 2155 HOH HOH A . X 8 HOH 156 2156 2156 HOH HOH A . X 8 HOH 157 2157 2157 HOH HOH A . X 8 HOH 158 2158 2158 HOH HOH A . X 8 HOH 159 2159 2159 HOH HOH A . X 8 HOH 160 2160 2160 HOH HOH A . X 8 HOH 161 2161 2161 HOH HOH A . X 8 HOH 162 2162 2162 HOH HOH A . X 8 HOH 163 2163 2163 HOH HOH A . X 8 HOH 164 2164 2164 HOH HOH A . X 8 HOH 165 2165 2165 HOH HOH A . X 8 HOH 166 2166 2166 HOH HOH A . X 8 HOH 167 2167 2167 HOH HOH A . X 8 HOH 168 2168 2168 HOH HOH A . X 8 HOH 169 2169 2169 HOH HOH A . X 8 HOH 170 2170 2170 HOH HOH A . X 8 HOH 171 2171 2171 HOH HOH A . X 8 HOH 172 2172 2172 HOH HOH A . X 8 HOH 173 2173 2173 HOH HOH A . X 8 HOH 174 2174 2174 HOH HOH A . X 8 HOH 175 2175 2175 HOH HOH A . X 8 HOH 176 2176 2176 HOH HOH A . X 8 HOH 177 2177 2177 HOH HOH A . X 8 HOH 178 2178 2178 HOH HOH A . X 8 HOH 179 2179 2179 HOH HOH A . X 8 HOH 180 2180 2180 HOH HOH A . X 8 HOH 181 2181 2181 HOH HOH A . X 8 HOH 182 2182 2182 HOH HOH A . X 8 HOH 183 2183 2183 HOH HOH A . X 8 HOH 184 2184 2184 HOH HOH A . X 8 HOH 185 2185 2185 HOH HOH A . X 8 HOH 186 2186 2186 HOH HOH A . X 8 HOH 187 2187 2187 HOH HOH A . X 8 HOH 188 2188 2188 HOH HOH A . X 8 HOH 189 2189 2189 HOH HOH A . X 8 HOH 190 2190 2190 HOH HOH A . X 8 HOH 191 2191 2191 HOH HOH A . X 8 HOH 192 2192 2192 HOH HOH A . X 8 HOH 193 2193 2193 HOH HOH A . X 8 HOH 194 2194 2194 HOH HOH A . X 8 HOH 195 2195 2195 HOH HOH A . X 8 HOH 196 2196 2196 HOH HOH A . X 8 HOH 197 2197 2197 HOH HOH A . X 8 HOH 198 2198 2198 HOH HOH A . X 8 HOH 199 2199 2199 HOH HOH A . X 8 HOH 200 2200 2200 HOH HOH A . X 8 HOH 201 2201 2201 HOH HOH A . X 8 HOH 202 2202 2202 HOH HOH A . X 8 HOH 203 2203 2203 HOH HOH A . X 8 HOH 204 2204 2204 HOH HOH A . X 8 HOH 205 2205 2205 HOH HOH A . X 8 HOH 206 2206 2206 HOH HOH A . X 8 HOH 207 2207 2207 HOH HOH A . X 8 HOH 208 2208 2208 HOH HOH A . X 8 HOH 209 2209 2209 HOH HOH A . X 8 HOH 210 2210 2210 HOH HOH A . X 8 HOH 211 2211 2211 HOH HOH A . X 8 HOH 212 2212 2212 HOH HOH A . X 8 HOH 213 2213 2213 HOH HOH A . X 8 HOH 214 2214 2214 HOH HOH A . X 8 HOH 215 2215 2215 HOH HOH A . X 8 HOH 216 2216 2216 HOH HOH A . X 8 HOH 217 2217 2217 HOH HOH A . X 8 HOH 218 2218 2218 HOH HOH A . X 8 HOH 219 2219 2219 HOH HOH A . X 8 HOH 220 2220 2220 HOH HOH A . X 8 HOH 221 2221 2221 HOH HOH A . X 8 HOH 222 2222 2222 HOH HOH A . X 8 HOH 223 2223 2223 HOH HOH A . X 8 HOH 224 2224 2224 HOH HOH A . X 8 HOH 225 2225 2225 HOH HOH A . X 8 HOH 226 2226 2226 HOH HOH A . X 8 HOH 227 2227 2227 HOH HOH A . X 8 HOH 228 2228 2228 HOH HOH A . X 8 HOH 229 2229 2229 HOH HOH A . X 8 HOH 230 2230 2230 HOH HOH A . X 8 HOH 231 2231 2231 HOH HOH A . X 8 HOH 232 2232 2232 HOH HOH A . X 8 HOH 233 2233 2233 HOH HOH A . X 8 HOH 234 2234 2234 HOH HOH A . X 8 HOH 235 2235 2235 HOH HOH A . X 8 HOH 236 2236 2236 HOH HOH A . X 8 HOH 237 2237 2237 HOH HOH A . X 8 HOH 238 2238 2238 HOH HOH A . X 8 HOH 239 2239 2239 HOH HOH A . X 8 HOH 240 2240 2240 HOH HOH A . X 8 HOH 241 2241 2241 HOH HOH A . X 8 HOH 242 2242 2242 HOH HOH A . X 8 HOH 243 2243 2243 HOH HOH A . X 8 HOH 244 2244 2244 HOH HOH A . X 8 HOH 245 2245 2245 HOH HOH A . X 8 HOH 246 2246 2246 HOH HOH A . X 8 HOH 247 2247 2247 HOH HOH A . X 8 HOH 248 2248 2248 HOH HOH A . X 8 HOH 249 2249 2249 HOH HOH A . X 8 HOH 250 2250 2250 HOH HOH A . X 8 HOH 251 2251 2251 HOH HOH A . X 8 HOH 252 2252 2252 HOH HOH A . X 8 HOH 253 2253 2253 HOH HOH A . X 8 HOH 254 2254 2254 HOH HOH A . X 8 HOH 255 2255 2255 HOH HOH A . X 8 HOH 256 2256 2256 HOH HOH A . X 8 HOH 257 2257 2257 HOH HOH A . X 8 HOH 258 2258 2258 HOH HOH A . X 8 HOH 259 2259 2259 HOH HOH A . X 8 HOH 260 2260 2260 HOH HOH A . X 8 HOH 261 2261 2261 HOH HOH A . X 8 HOH 262 2262 2262 HOH HOH A . X 8 HOH 263 2263 2263 HOH HOH A . X 8 HOH 264 2264 2264 HOH HOH A . X 8 HOH 265 2265 2265 HOH HOH A . X 8 HOH 266 2266 2266 HOH HOH A . X 8 HOH 267 2267 2267 HOH HOH A . X 8 HOH 268 2268 2268 HOH HOH A . X 8 HOH 269 2269 2269 HOH HOH A . X 8 HOH 270 2270 2270 HOH HOH A . X 8 HOH 271 2271 2271 HOH HOH A . X 8 HOH 272 2272 2272 HOH HOH A . X 8 HOH 273 2273 2273 HOH HOH A . X 8 HOH 274 2274 2274 HOH HOH A . X 8 HOH 275 2275 2275 HOH HOH A . X 8 HOH 276 2276 2276 HOH HOH A . X 8 HOH 277 2277 2277 HOH HOH A . X 8 HOH 278 2278 2278 HOH HOH A . X 8 HOH 279 2279 2279 HOH HOH A . X 8 HOH 280 2280 2280 HOH HOH A . X 8 HOH 281 2281 2281 HOH HOH A . X 8 HOH 282 2282 2282 HOH HOH A . X 8 HOH 283 2283 2283 HOH HOH A . X 8 HOH 284 2284 2284 HOH HOH A . X 8 HOH 285 2285 2285 HOH HOH A . X 8 HOH 286 2286 2286 HOH HOH A . X 8 HOH 287 2287 2287 HOH HOH A . X 8 HOH 288 2288 2288 HOH HOH A . X 8 HOH 289 2289 2289 HOH HOH A . X 8 HOH 290 2290 2290 HOH HOH A . X 8 HOH 291 2291 2291 HOH HOH A . X 8 HOH 292 2292 2292 HOH HOH A . X 8 HOH 293 2293 2293 HOH HOH A . X 8 HOH 294 2294 2294 HOH HOH A . X 8 HOH 295 2295 2295 HOH HOH A . X 8 HOH 296 2296 2296 HOH HOH A . X 8 HOH 297 2297 2297 HOH HOH A . X 8 HOH 298 2298 2298 HOH HOH A . X 8 HOH 299 2299 2299 HOH HOH A . X 8 HOH 300 2300 2300 HOH HOH A . X 8 HOH 301 2301 2301 HOH HOH A . X 8 HOH 302 2302 2302 HOH HOH A . X 8 HOH 303 2303 2303 HOH HOH A . X 8 HOH 304 2304 2304 HOH HOH A . X 8 HOH 305 2305 2305 HOH HOH A . X 8 HOH 306 2306 2306 HOH HOH A . X 8 HOH 307 2307 2307 HOH HOH A . X 8 HOH 308 2308 2308 HOH HOH A . X 8 HOH 309 2309 2309 HOH HOH A . X 8 HOH 310 2310 2310 HOH HOH A . X 8 HOH 311 2311 2311 HOH HOH A . X 8 HOH 312 2312 2312 HOH HOH A . X 8 HOH 313 2313 2313 HOH HOH A . X 8 HOH 314 2314 2314 HOH HOH A . X 8 HOH 315 2315 2315 HOH HOH A . X 8 HOH 316 2316 2316 HOH HOH A . X 8 HOH 317 2317 2317 HOH HOH A . X 8 HOH 318 2318 2318 HOH HOH A . X 8 HOH 319 2319 2319 HOH HOH A . X 8 HOH 320 2320 2320 HOH HOH A . X 8 HOH 321 2321 2321 HOH HOH A . X 8 HOH 322 2322 2322 HOH HOH A . X 8 HOH 323 2323 2323 HOH HOH A . X 8 HOH 324 2324 2324 HOH HOH A . X 8 HOH 325 2325 2325 HOH HOH A . X 8 HOH 326 2326 2326 HOH HOH A . X 8 HOH 327 2327 2327 HOH HOH A . X 8 HOH 328 2328 2328 HOH HOH A . X 8 HOH 329 2329 2329 HOH HOH A . X 8 HOH 330 2330 2330 HOH HOH A . X 8 HOH 331 2331 2331 HOH HOH A . X 8 HOH 332 2332 2332 HOH HOH A . X 8 HOH 333 2333 2333 HOH HOH A . X 8 HOH 334 2334 2334 HOH HOH A . X 8 HOH 335 2335 2335 HOH HOH A . X 8 HOH 336 2336 2336 HOH HOH A . X 8 HOH 337 2337 2337 HOH HOH A . X 8 HOH 338 2338 2338 HOH HOH A . X 8 HOH 339 2339 2339 HOH HOH A . X 8 HOH 340 2340 2340 HOH HOH A . X 8 HOH 341 2341 2341 HOH HOH A . X 8 HOH 342 2342 2342 HOH HOH A . X 8 HOH 343 2343 2343 HOH HOH A . X 8 HOH 344 2344 2344 HOH HOH A . X 8 HOH 345 2345 2345 HOH HOH A . X 8 HOH 346 2346 2346 HOH HOH A . X 8 HOH 347 2347 2347 HOH HOH A . X 8 HOH 348 2348 2348 HOH HOH A . X 8 HOH 349 2349 2349 HOH HOH A . X 8 HOH 350 2350 2350 HOH HOH A . X 8 HOH 351 2351 2351 HOH HOH A . X 8 HOH 352 2352 2352 HOH HOH A . X 8 HOH 353 2353 2353 HOH HOH A . X 8 HOH 354 2354 2354 HOH HOH A . X 8 HOH 355 2355 2355 HOH HOH A . X 8 HOH 356 2356 2356 HOH HOH A . X 8 HOH 357 2357 2357 HOH HOH A . X 8 HOH 358 2358 2358 HOH HOH A . X 8 HOH 359 2359 2359 HOH HOH A . X 8 HOH 360 2360 2360 HOH HOH A . X 8 HOH 361 2361 2361 HOH HOH A . X 8 HOH 362 2362 2362 HOH HOH A . X 8 HOH 363 2363 2363 HOH HOH A . X 8 HOH 364 2364 2364 HOH HOH A . X 8 HOH 365 2365 2365 HOH HOH A . X 8 HOH 366 2366 2366 HOH HOH A . X 8 HOH 367 2367 2367 HOH HOH A . X 8 HOH 368 2368 2368 HOH HOH A . X 8 HOH 369 2369 2369 HOH HOH A . X 8 HOH 370 2370 2370 HOH HOH A . X 8 HOH 371 2371 2371 HOH HOH A . X 8 HOH 372 2372 2372 HOH HOH A . X 8 HOH 373 2373 2373 HOH HOH A . X 8 HOH 374 2374 2374 HOH HOH A . X 8 HOH 375 2375 2375 HOH HOH A . X 8 HOH 376 2376 2376 HOH HOH A . X 8 HOH 377 2377 2377 HOH HOH A . X 8 HOH 378 2378 2378 HOH HOH A . X 8 HOH 379 2379 2379 HOH HOH A . X 8 HOH 380 2380 2380 HOH HOH A . X 8 HOH 381 2381 2381 HOH HOH A . X 8 HOH 382 2382 2382 HOH HOH A . X 8 HOH 383 2383 2383 HOH HOH A . X 8 HOH 384 2384 2384 HOH HOH A . X 8 HOH 385 2385 2385 HOH HOH A . X 8 HOH 386 2386 2386 HOH HOH A . X 8 HOH 387 2387 2387 HOH HOH A . X 8 HOH 388 2388 2388 HOH HOH A . X 8 HOH 389 2389 2389 HOH HOH A . X 8 HOH 390 2390 2390 HOH HOH A . X 8 HOH 391 2391 2391 HOH HOH A . X 8 HOH 392 2392 2392 HOH HOH A . X 8 HOH 393 2393 2393 HOH HOH A . X 8 HOH 394 2394 2394 HOH HOH A . X 8 HOH 395 2395 2395 HOH HOH A . X 8 HOH 396 2396 2396 HOH HOH A . X 8 HOH 397 2397 2397 HOH HOH A . X 8 HOH 398 2398 2398 HOH HOH A . X 8 HOH 399 2399 2399 HOH HOH A . X 8 HOH 400 2400 2400 HOH HOH A . X 8 HOH 401 2401 2401 HOH HOH A . X 8 HOH 402 2402 2402 HOH HOH A . X 8 HOH 403 2403 2403 HOH HOH A . X 8 HOH 404 2404 2404 HOH HOH A . X 8 HOH 405 2405 2405 HOH HOH A . X 8 HOH 406 2406 2406 HOH HOH A . X 8 HOH 407 2407 2407 HOH HOH A . X 8 HOH 408 2408 2408 HOH HOH A . X 8 HOH 409 2409 2409 HOH HOH A . X 8 HOH 410 2410 2410 HOH HOH A . X 8 HOH 411 2411 2411 HOH HOH A . X 8 HOH 412 2412 2412 HOH HOH A . X 8 HOH 413 2413 2413 HOH HOH A . X 8 HOH 414 2414 2414 HOH HOH A . X 8 HOH 415 2415 2415 HOH HOH A . X 8 HOH 416 2416 2416 HOH HOH A . X 8 HOH 417 2417 2417 HOH HOH A . X 8 HOH 418 2418 2418 HOH HOH A . X 8 HOH 419 2419 2419 HOH HOH A . X 8 HOH 420 2420 2420 HOH HOH A . X 8 HOH 421 2421 2421 HOH HOH A . X 8 HOH 422 2422 2422 HOH HOH A . X 8 HOH 423 2423 2423 HOH HOH A . X 8 HOH 424 2424 2424 HOH HOH A . X 8 HOH 425 2425 2425 HOH HOH A . X 8 HOH 426 2426 2426 HOH HOH A . X 8 HOH 427 2427 2427 HOH HOH A . X 8 HOH 428 2428 2428 HOH HOH A . X 8 HOH 429 2429 2429 HOH HOH A . X 8 HOH 430 2430 2430 HOH HOH A . X 8 HOH 431 2431 2431 HOH HOH A . X 8 HOH 432 2432 2432 HOH HOH A . X 8 HOH 433 2433 2433 HOH HOH A . X 8 HOH 434 2434 2434 HOH HOH A . X 8 HOH 435 2435 2435 HOH HOH A . X 8 HOH 436 2436 2436 HOH HOH A . X 8 HOH 437 2437 2437 HOH HOH A . X 8 HOH 438 2438 2438 HOH HOH A . X 8 HOH 439 2439 2439 HOH HOH A . X 8 HOH 440 2440 2440 HOH HOH A . X 8 HOH 441 2441 2441 HOH HOH A . X 8 HOH 442 2442 2442 HOH HOH A . X 8 HOH 443 2443 2443 HOH HOH A . X 8 HOH 444 2444 2444 HOH HOH A . X 8 HOH 445 2445 2445 HOH HOH A . X 8 HOH 446 2446 2446 HOH HOH A . X 8 HOH 447 2447 2447 HOH HOH A . X 8 HOH 448 2448 2448 HOH HOH A . X 8 HOH 449 2449 2449 HOH HOH A . X 8 HOH 450 2450 2450 HOH HOH A . X 8 HOH 451 2451 2451 HOH HOH A . X 8 HOH 452 2452 2452 HOH HOH A . X 8 HOH 453 2453 2453 HOH HOH A . X 8 HOH 454 2454 2454 HOH HOH A . X 8 HOH 455 2455 2455 HOH HOH A . X 8 HOH 456 2456 2456 HOH HOH A . X 8 HOH 457 2457 2457 HOH HOH A . X 8 HOH 458 2458 2458 HOH HOH A . X 8 HOH 459 2459 2459 HOH HOH A . X 8 HOH 460 2460 2460 HOH HOH A . X 8 HOH 461 2461 2461 HOH HOH A . X 8 HOH 462 2462 2462 HOH HOH A . X 8 HOH 463 2463 2463 HOH HOH A . X 8 HOH 464 2464 2464 HOH HOH A . X 8 HOH 465 2465 2465 HOH HOH A . X 8 HOH 466 2466 2466 HOH HOH A . X 8 HOH 467 2467 2467 HOH HOH A . X 8 HOH 468 2468 2468 HOH HOH A . X 8 HOH 469 2469 2469 HOH HOH A . X 8 HOH 470 2470 2470 HOH HOH A . X 8 HOH 471 2471 2471 HOH HOH A . X 8 HOH 472 2472 2472 HOH HOH A . X 8 HOH 473 2473 2473 HOH HOH A . X 8 HOH 474 2474 2474 HOH HOH A . X 8 HOH 475 2475 2475 HOH HOH A . X 8 HOH 476 2476 2476 HOH HOH A . X 8 HOH 477 2477 2477 HOH HOH A . X 8 HOH 478 2478 2478 HOH HOH A . X 8 HOH 479 2479 2479 HOH HOH A . X 8 HOH 480 2480 2480 HOH HOH A . X 8 HOH 481 2481 2481 HOH HOH A . X 8 HOH 482 2482 2482 HOH HOH A . X 8 HOH 483 2483 2483 HOH HOH A . Y 8 HOH 1 2001 2001 HOH HOH B . Y 8 HOH 2 2002 2002 HOH HOH B . Y 8 HOH 3 2003 2003 HOH HOH B . Y 8 HOH 4 2004 2004 HOH HOH B . Y 8 HOH 5 2005 2005 HOH HOH B . Y 8 HOH 6 2006 2006 HOH HOH B . Y 8 HOH 7 2007 2007 HOH HOH B . Y 8 HOH 8 2008 2008 HOH HOH B . Y 8 HOH 9 2009 2009 HOH HOH B . Y 8 HOH 10 2010 2010 HOH HOH B . Y 8 HOH 11 2011 2011 HOH HOH B . Y 8 HOH 12 2012 2012 HOH HOH B . Y 8 HOH 13 2013 2013 HOH HOH B . Y 8 HOH 14 2014 2014 HOH HOH B . Y 8 HOH 15 2015 2015 HOH HOH B . Y 8 HOH 16 2016 2016 HOH HOH B . Y 8 HOH 17 2017 2017 HOH HOH B . Y 8 HOH 18 2018 2018 HOH HOH B . Y 8 HOH 19 2019 2019 HOH HOH B . Y 8 HOH 20 2020 2020 HOH HOH B . Y 8 HOH 21 2021 2021 HOH HOH B . Y 8 HOH 22 2022 2022 HOH HOH B . Y 8 HOH 23 2023 2023 HOH HOH B . Y 8 HOH 24 2024 2024 HOH HOH B . Y 8 HOH 25 2025 2025 HOH HOH B . Y 8 HOH 26 2026 2026 HOH HOH B . Y 8 HOH 27 2027 2027 HOH HOH B . Y 8 HOH 28 2028 2028 HOH HOH B . Y 8 HOH 29 2029 2029 HOH HOH B . Y 8 HOH 30 2030 2030 HOH HOH B . Y 8 HOH 31 2031 2031 HOH HOH B . Y 8 HOH 32 2032 2032 HOH HOH B . Y 8 HOH 33 2033 2033 HOH HOH B . Y 8 HOH 34 2034 2034 HOH HOH B . Y 8 HOH 35 2035 2035 HOH HOH B . Y 8 HOH 36 2036 2036 HOH HOH B . Y 8 HOH 37 2037 2037 HOH HOH B . Y 8 HOH 38 2038 2038 HOH HOH B . Y 8 HOH 39 2039 2039 HOH HOH B . Y 8 HOH 40 2040 2040 HOH HOH B . Y 8 HOH 41 2041 2041 HOH HOH B . Y 8 HOH 42 2042 2042 HOH HOH B . Y 8 HOH 43 2043 2043 HOH HOH B . Y 8 HOH 44 2044 2044 HOH HOH B . Y 8 HOH 45 2045 2045 HOH HOH B . Y 8 HOH 46 2046 2046 HOH HOH B . Y 8 HOH 47 2047 2047 HOH HOH B . Y 8 HOH 48 2048 2048 HOH HOH B . Y 8 HOH 49 2049 2049 HOH HOH B . Y 8 HOH 50 2050 2050 HOH HOH B . Y 8 HOH 51 2051 2051 HOH HOH B . Y 8 HOH 52 2052 2052 HOH HOH B . Y 8 HOH 53 2053 2053 HOH HOH B . Y 8 HOH 54 2054 2054 HOH HOH B . Y 8 HOH 55 2055 2055 HOH HOH B . Y 8 HOH 56 2056 2056 HOH HOH B . Y 8 HOH 57 2057 2057 HOH HOH B . Y 8 HOH 58 2058 2058 HOH HOH B . Y 8 HOH 59 2059 2059 HOH HOH B . Y 8 HOH 60 2060 2060 HOH HOH B . Y 8 HOH 61 2061 2061 HOH HOH B . Y 8 HOH 62 2062 2062 HOH HOH B . Y 8 HOH 63 2063 2063 HOH HOH B . Y 8 HOH 64 2064 2064 HOH HOH B . Y 8 HOH 65 2065 2065 HOH HOH B . Y 8 HOH 66 2066 2066 HOH HOH B . Y 8 HOH 67 2067 2067 HOH HOH B . Y 8 HOH 68 2068 2068 HOH HOH B . Y 8 HOH 69 2069 2069 HOH HOH B . Y 8 HOH 70 2070 2070 HOH HOH B . Y 8 HOH 71 2071 2071 HOH HOH B . Y 8 HOH 72 2072 2072 HOH HOH B . Y 8 HOH 73 2073 2073 HOH HOH B . Y 8 HOH 74 2074 2074 HOH HOH B . Y 8 HOH 75 2075 2075 HOH HOH B . Y 8 HOH 76 2076 2076 HOH HOH B . Y 8 HOH 77 2077 2077 HOH HOH B . Y 8 HOH 78 2078 2078 HOH HOH B . Y 8 HOH 79 2079 2079 HOH HOH B . Y 8 HOH 80 2080 2080 HOH HOH B . Y 8 HOH 81 2081 2081 HOH HOH B . Y 8 HOH 82 2082 2082 HOH HOH B . Y 8 HOH 83 2083 2083 HOH HOH B . Y 8 HOH 84 2084 2084 HOH HOH B . Y 8 HOH 85 2085 2085 HOH HOH B . Y 8 HOH 86 2086 2086 HOH HOH B . Y 8 HOH 87 2087 2087 HOH HOH B . Y 8 HOH 88 2088 2088 HOH HOH B . Y 8 HOH 89 2089 2089 HOH HOH B . Y 8 HOH 90 2090 2090 HOH HOH B . Y 8 HOH 91 2091 2091 HOH HOH B . Y 8 HOH 92 2092 2092 HOH HOH B . Y 8 HOH 93 2093 2093 HOH HOH B . Y 8 HOH 94 2094 2094 HOH HOH B . Y 8 HOH 95 2095 2095 HOH HOH B . Y 8 HOH 96 2096 2096 HOH HOH B . Y 8 HOH 97 2097 2097 HOH HOH B . Y 8 HOH 98 2098 2098 HOH HOH B . Y 8 HOH 99 2099 2099 HOH HOH B . Y 8 HOH 100 2100 2100 HOH HOH B . Y 8 HOH 101 2101 2101 HOH HOH B . Y 8 HOH 102 2102 2102 HOH HOH B . Y 8 HOH 103 2103 2103 HOH HOH B . Y 8 HOH 104 2104 2104 HOH HOH B . Y 8 HOH 105 2105 2105 HOH HOH B . Y 8 HOH 106 2106 2106 HOH HOH B . Y 8 HOH 107 2107 2107 HOH HOH B . Y 8 HOH 108 2108 2108 HOH HOH B . Y 8 HOH 109 2109 2109 HOH HOH B . Y 8 HOH 110 2110 2110 HOH HOH B . Y 8 HOH 111 2111 2111 HOH HOH B . Y 8 HOH 112 2112 2112 HOH HOH B . Y 8 HOH 113 2113 2113 HOH HOH B . Y 8 HOH 114 2114 2114 HOH HOH B . Y 8 HOH 115 2115 2115 HOH HOH B . Y 8 HOH 116 2116 2116 HOH HOH B . Y 8 HOH 117 2117 2117 HOH HOH B . Y 8 HOH 118 2118 2118 HOH HOH B . Y 8 HOH 119 2119 2119 HOH HOH B . Y 8 HOH 120 2120 2120 HOH HOH B . Y 8 HOH 121 2121 2121 HOH HOH B . Y 8 HOH 122 2122 2122 HOH HOH B . Y 8 HOH 123 2123 2123 HOH HOH B . Y 8 HOH 124 2124 2124 HOH HOH B . Y 8 HOH 125 2125 2125 HOH HOH B . Y 8 HOH 126 2126 2126 HOH HOH B . Y 8 HOH 127 2127 2127 HOH HOH B . Y 8 HOH 128 2128 2128 HOH HOH B . Y 8 HOH 129 2129 2129 HOH HOH B . Y 8 HOH 130 2130 2130 HOH HOH B . Y 8 HOH 131 2131 2131 HOH HOH B . Y 8 HOH 132 2132 2132 HOH HOH B . Y 8 HOH 133 2133 2133 HOH HOH B . Y 8 HOH 134 2134 2134 HOH HOH B . Y 8 HOH 135 2135 2135 HOH HOH B . Y 8 HOH 136 2136 2136 HOH HOH B . Y 8 HOH 137 2137 2137 HOH HOH B . Y 8 HOH 138 2138 2138 HOH HOH B . Y 8 HOH 139 2139 2139 HOH HOH B . Y 8 HOH 140 2140 2140 HOH HOH B . Y 8 HOH 141 2141 2141 HOH HOH B . Y 8 HOH 142 2142 2142 HOH HOH B . Y 8 HOH 143 2143 2143 HOH HOH B . Y 8 HOH 144 2144 2144 HOH HOH B . Y 8 HOH 145 2145 2145 HOH HOH B . Y 8 HOH 146 2146 2146 HOH HOH B . Y 8 HOH 147 2147 2147 HOH HOH B . Y 8 HOH 148 2148 2148 HOH HOH B . Y 8 HOH 149 2149 2149 HOH HOH B . Y 8 HOH 150 2150 2150 HOH HOH B . Y 8 HOH 151 2151 2151 HOH HOH B . Y 8 HOH 152 2152 2152 HOH HOH B . Y 8 HOH 153 2153 2153 HOH HOH B . Y 8 HOH 154 2154 2154 HOH HOH B . Y 8 HOH 155 2155 2155 HOH HOH B . Y 8 HOH 156 2156 2156 HOH HOH B . Y 8 HOH 157 2157 2157 HOH HOH B . Y 8 HOH 158 2158 2158 HOH HOH B . Y 8 HOH 159 2159 2159 HOH HOH B . Y 8 HOH 160 2160 2160 HOH HOH B . Y 8 HOH 161 2161 2161 HOH HOH B . Y 8 HOH 162 2162 2162 HOH HOH B . Y 8 HOH 163 2163 2163 HOH HOH B . Y 8 HOH 164 2164 2164 HOH HOH B . Y 8 HOH 165 2165 2165 HOH HOH B . Y 8 HOH 166 2166 2166 HOH HOH B . Y 8 HOH 167 2167 2167 HOH HOH B . Y 8 HOH 168 2168 2168 HOH HOH B . Y 8 HOH 169 2169 2169 HOH HOH B . Y 8 HOH 170 2170 2170 HOH HOH B . Y 8 HOH 171 2171 2171 HOH HOH B . Y 8 HOH 172 2172 2172 HOH HOH B . Y 8 HOH 173 2173 2173 HOH HOH B . Y 8 HOH 174 2174 2174 HOH HOH B . Y 8 HOH 175 2175 2175 HOH HOH B . Y 8 HOH 176 2176 2176 HOH HOH B . Y 8 HOH 177 2177 2177 HOH HOH B . Y 8 HOH 178 2178 2178 HOH HOH B . Y 8 HOH 179 2179 2179 HOH HOH B . Y 8 HOH 180 2180 2180 HOH HOH B . Y 8 HOH 181 2181 2181 HOH HOH B . Y 8 HOH 182 2182 2182 HOH HOH B . Y 8 HOH 183 2183 2183 HOH HOH B . Y 8 HOH 184 2184 2184 HOH HOH B . Y 8 HOH 185 2185 2185 HOH HOH B . Y 8 HOH 186 2186 2186 HOH HOH B . Y 8 HOH 187 2187 2187 HOH HOH B . Y 8 HOH 188 2188 2188 HOH HOH B . Y 8 HOH 189 2189 2189 HOH HOH B . Y 8 HOH 190 2190 2190 HOH HOH B . Y 8 HOH 191 2191 2191 HOH HOH B . Y 8 HOH 192 2192 2192 HOH HOH B . Y 8 HOH 193 2193 2193 HOH HOH B . Y 8 HOH 194 2194 2194 HOH HOH B . Y 8 HOH 195 2195 2195 HOH HOH B . Y 8 HOH 196 2196 2196 HOH HOH B . Y 8 HOH 197 2197 2197 HOH HOH B . Y 8 HOH 198 2198 2198 HOH HOH B . Y 8 HOH 199 2199 2199 HOH HOH B . Y 8 HOH 200 2200 2200 HOH HOH B . Y 8 HOH 201 2201 2201 HOH HOH B . Y 8 HOH 202 2202 2202 HOH HOH B . Y 8 HOH 203 2203 2203 HOH HOH B . Y 8 HOH 204 2204 2204 HOH HOH B . Y 8 HOH 205 2205 2205 HOH HOH B . Y 8 HOH 206 2206 2206 HOH HOH B . Y 8 HOH 207 2207 2207 HOH HOH B . Y 8 HOH 208 2208 2208 HOH HOH B . Y 8 HOH 209 2209 2209 HOH HOH B . Y 8 HOH 210 2210 2210 HOH HOH B . Y 8 HOH 211 2211 2211 HOH HOH B . Y 8 HOH 212 2212 2212 HOH HOH B . Y 8 HOH 213 2213 2213 HOH HOH B . Y 8 HOH 214 2214 2214 HOH HOH B . Y 8 HOH 215 2215 2215 HOH HOH B . Y 8 HOH 216 2216 2216 HOH HOH B . Y 8 HOH 217 2217 2217 HOH HOH B . Y 8 HOH 218 2218 2218 HOH HOH B . Y 8 HOH 219 2219 2219 HOH HOH B . Y 8 HOH 220 2220 2220 HOH HOH B . Y 8 HOH 221 2221 2221 HOH HOH B . Y 8 HOH 222 2222 2222 HOH HOH B . Y 8 HOH 223 2223 2223 HOH HOH B . Y 8 HOH 224 2224 2224 HOH HOH B . Y 8 HOH 225 2225 2225 HOH HOH B . Y 8 HOH 226 2226 2226 HOH HOH B . Y 8 HOH 227 2227 2227 HOH HOH B . Y 8 HOH 228 2228 2228 HOH HOH B . Y 8 HOH 229 2229 2229 HOH HOH B . Y 8 HOH 230 2230 2230 HOH HOH B . Y 8 HOH 231 2231 2231 HOH HOH B . Y 8 HOH 232 2232 2232 HOH HOH B . Y 8 HOH 233 2233 2233 HOH HOH B . Y 8 HOH 234 2234 2234 HOH HOH B . Y 8 HOH 235 2235 2235 HOH HOH B . Y 8 HOH 236 2236 2236 HOH HOH B . Y 8 HOH 237 2237 2237 HOH HOH B . Y 8 HOH 238 2238 2238 HOH HOH B . Y 8 HOH 239 2239 2239 HOH HOH B . Y 8 HOH 240 2240 2240 HOH HOH B . Y 8 HOH 241 2241 2241 HOH HOH B . Y 8 HOH 242 2242 2242 HOH HOH B . Y 8 HOH 243 2243 2243 HOH HOH B . Y 8 HOH 244 2244 2244 HOH HOH B . Y 8 HOH 245 2245 2245 HOH HOH B . Y 8 HOH 246 2246 2246 HOH HOH B . Y 8 HOH 247 2247 2247 HOH HOH B . Y 8 HOH 248 2248 2248 HOH HOH B . Y 8 HOH 249 2249 2249 HOH HOH B . Y 8 HOH 250 2250 2250 HOH HOH B . Y 8 HOH 251 2251 2251 HOH HOH B . Y 8 HOH 252 2252 2252 HOH HOH B . Y 8 HOH 253 2253 2253 HOH HOH B . Y 8 HOH 254 2254 2254 HOH HOH B . Y 8 HOH 255 2255 2255 HOH HOH B . Y 8 HOH 256 2256 2256 HOH HOH B . Y 8 HOH 257 2257 2257 HOH HOH B . Y 8 HOH 258 2258 2258 HOH HOH B . Y 8 HOH 259 2259 2259 HOH HOH B . Y 8 HOH 260 2260 2260 HOH HOH B . Y 8 HOH 261 2261 2261 HOH HOH B . Y 8 HOH 262 2262 2262 HOH HOH B . Y 8 HOH 263 2263 2263 HOH HOH B . Y 8 HOH 264 2264 2264 HOH HOH B . Y 8 HOH 265 2265 2265 HOH HOH B . Y 8 HOH 266 2266 2266 HOH HOH B . Y 8 HOH 267 2267 2267 HOH HOH B . Y 8 HOH 268 2268 2268 HOH HOH B . Y 8 HOH 269 2269 2269 HOH HOH B . Y 8 HOH 270 2270 2270 HOH HOH B . Y 8 HOH 271 2271 2271 HOH HOH B . Y 8 HOH 272 2272 2272 HOH HOH B . Y 8 HOH 273 2273 2273 HOH HOH B . Y 8 HOH 274 2274 2274 HOH HOH B . Y 8 HOH 275 2275 2275 HOH HOH B . Y 8 HOH 276 2276 2276 HOH HOH B . Y 8 HOH 277 2277 2277 HOH HOH B . Y 8 HOH 278 2278 2278 HOH HOH B . Y 8 HOH 279 2279 2279 HOH HOH B . Y 8 HOH 280 2280 2280 HOH HOH B . Y 8 HOH 281 2281 2281 HOH HOH B . Y 8 HOH 282 2282 2282 HOH HOH B . Y 8 HOH 283 2283 2283 HOH HOH B . Y 8 HOH 284 2284 2284 HOH HOH B . Y 8 HOH 285 2285 2285 HOH HOH B . Y 8 HOH 286 2286 2286 HOH HOH B . Y 8 HOH 287 2287 2287 HOH HOH B . Y 8 HOH 288 2288 2288 HOH HOH B . Y 8 HOH 289 2289 2289 HOH HOH B . Y 8 HOH 290 2290 2290 HOH HOH B . Y 8 HOH 291 2291 2291 HOH HOH B . Y 8 HOH 292 2292 2292 HOH HOH B . Y 8 HOH 293 2293 2293 HOH HOH B . Y 8 HOH 294 2294 2294 HOH HOH B . Y 8 HOH 295 2295 2295 HOH HOH B . Y 8 HOH 296 2296 2296 HOH HOH B . Y 8 HOH 297 2297 2297 HOH HOH B . Y 8 HOH 298 2298 2298 HOH HOH B . Y 8 HOH 299 2299 2299 HOH HOH B . Y 8 HOH 300 2300 2300 HOH HOH B . Y 8 HOH 301 2301 2301 HOH HOH B . Y 8 HOH 302 2302 2302 HOH HOH B . Y 8 HOH 303 2303 2303 HOH HOH B . Y 8 HOH 304 2304 2304 HOH HOH B . Y 8 HOH 305 2305 2305 HOH HOH B . Y 8 HOH 306 2306 2306 HOH HOH B . Y 8 HOH 307 2307 2307 HOH HOH B . Y 8 HOH 308 2308 2308 HOH HOH B . Y 8 HOH 309 2309 2309 HOH HOH B . Y 8 HOH 310 2310 2310 HOH HOH B . Y 8 HOH 311 2311 2311 HOH HOH B . Y 8 HOH 312 2312 2312 HOH HOH B . Y 8 HOH 313 2313 2313 HOH HOH B . Y 8 HOH 314 2314 2314 HOH HOH B . Y 8 HOH 315 2315 2315 HOH HOH B . Y 8 HOH 316 2316 2316 HOH HOH B . Y 8 HOH 317 2317 2317 HOH HOH B . Y 8 HOH 318 2318 2318 HOH HOH B . Y 8 HOH 319 2319 2319 HOH HOH B . Y 8 HOH 320 2320 2320 HOH HOH B . Y 8 HOH 321 2321 2321 HOH HOH B . Y 8 HOH 322 2322 2322 HOH HOH B . Y 8 HOH 323 2323 2323 HOH HOH B . Y 8 HOH 324 2324 2324 HOH HOH B . Y 8 HOH 325 2325 2325 HOH HOH B . Y 8 HOH 326 2326 2326 HOH HOH B . Y 8 HOH 327 2327 2327 HOH HOH B . Y 8 HOH 328 2328 2328 HOH HOH B . Y 8 HOH 329 2329 2329 HOH HOH B . Y 8 HOH 330 2330 2330 HOH HOH B . Y 8 HOH 331 2331 2331 HOH HOH B . Y 8 HOH 332 2332 2332 HOH HOH B . Y 8 HOH 333 2333 2333 HOH HOH B . Y 8 HOH 334 2334 2334 HOH HOH B . Y 8 HOH 335 2335 2335 HOH HOH B . Y 8 HOH 336 2336 2336 HOH HOH B . Y 8 HOH 337 2337 2337 HOH HOH B . Y 8 HOH 338 2338 2338 HOH HOH B . Y 8 HOH 339 2339 2339 HOH HOH B . Y 8 HOH 340 2340 2340 HOH HOH B . Y 8 HOH 341 2341 2341 HOH HOH B . Y 8 HOH 342 2342 2342 HOH HOH B . Y 8 HOH 343 2343 2343 HOH HOH B . Y 8 HOH 344 2344 2344 HOH HOH B . Y 8 HOH 345 2345 2345 HOH HOH B . Y 8 HOH 346 2346 2346 HOH HOH B . Y 8 HOH 347 2347 2347 HOH HOH B . Y 8 HOH 348 2348 2348 HOH HOH B . Y 8 HOH 349 2349 2349 HOH HOH B . Y 8 HOH 350 2350 2350 HOH HOH B . Y 8 HOH 351 2351 2351 HOH HOH B . Y 8 HOH 352 2352 2352 HOH HOH B . Y 8 HOH 353 2353 2353 HOH HOH B . Y 8 HOH 354 2354 2354 HOH HOH B . Y 8 HOH 355 2355 2355 HOH HOH B . Y 8 HOH 356 2356 2356 HOH HOH B . Y 8 HOH 357 2357 2357 HOH HOH B . Y 8 HOH 358 2358 2358 HOH HOH B . Y 8 HOH 359 2359 2359 HOH HOH B . Y 8 HOH 360 2360 2360 HOH HOH B . Y 8 HOH 361 2361 2361 HOH HOH B . Y 8 HOH 362 2362 2362 HOH HOH B . Y 8 HOH 363 2363 2363 HOH HOH B . Y 8 HOH 364 2364 2364 HOH HOH B . Y 8 HOH 365 2365 2365 HOH HOH B . Y 8 HOH 366 2366 2366 HOH HOH B . Y 8 HOH 367 2367 2367 HOH HOH B . Y 8 HOH 368 2368 2368 HOH HOH B . Y 8 HOH 369 2369 2369 HOH HOH B . Y 8 HOH 370 2370 2370 HOH HOH B . Y 8 HOH 371 2371 2371 HOH HOH B . Y 8 HOH 372 2372 2372 HOH HOH B . Y 8 HOH 373 2373 2373 HOH HOH B . Y 8 HOH 374 2374 2374 HOH HOH B . Y 8 HOH 375 2375 2375 HOH HOH B . Y 8 HOH 376 2376 2376 HOH HOH B . Y 8 HOH 377 2377 2377 HOH HOH B . Y 8 HOH 378 2378 2378 HOH HOH B . Y 8 HOH 379 2379 2379 HOH HOH B . Y 8 HOH 380 2380 2380 HOH HOH B . Y 8 HOH 381 2381 2381 HOH HOH B . Y 8 HOH 382 2382 2382 HOH HOH B . Y 8 HOH 383 2383 2383 HOH HOH B . Y 8 HOH 384 2384 2384 HOH HOH B . Y 8 HOH 385 2385 2385 HOH HOH B . Y 8 HOH 386 2386 2386 HOH HOH B . Y 8 HOH 387 2387 2387 HOH HOH B . Y 8 HOH 388 2388 2388 HOH HOH B . Y 8 HOH 389 2389 2389 HOH HOH B . Y 8 HOH 390 2390 2390 HOH HOH B . Y 8 HOH 391 2391 2391 HOH HOH B . Y 8 HOH 392 2392 2392 HOH HOH B . Y 8 HOH 393 2393 2393 HOH HOH B . Y 8 HOH 394 2394 2394 HOH HOH B . Y 8 HOH 395 2395 2395 HOH HOH B . Y 8 HOH 396 2396 2396 HOH HOH B . Y 8 HOH 397 2397 2397 HOH HOH B . Y 8 HOH 398 2398 2398 HOH HOH B . Y 8 HOH 399 2399 2399 HOH HOH B . Y 8 HOH 400 2400 2400 HOH HOH B . Y 8 HOH 401 2401 2401 HOH HOH B . Y 8 HOH 402 2402 2402 HOH HOH B . Y 8 HOH 403 2403 2403 HOH HOH B . Y 8 HOH 404 2404 2404 HOH HOH B . Y 8 HOH 405 2405 2405 HOH HOH B . Y 8 HOH 406 2406 2406 HOH HOH B . Y 8 HOH 407 2407 2407 HOH HOH B . Y 8 HOH 408 2408 2408 HOH HOH B . Y 8 HOH 409 2409 2409 HOH HOH B . Y 8 HOH 410 2410 2410 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 280 A ASN 282 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 347 A ASN 349 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 413 A ASN 415 ? ASN 'GLYCOSYLATION SITE' 4 B ASN 280 B ASN 282 ? ASN 'GLYCOSYLATION SITE' 5 B ASN 347 B ASN 349 ? ASN 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA monomeric 1 2 author_and_software_defined_assembly PISA monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,C,D,E,F,G,H,I,J,K,L,M,N,X 2 1 B,O,P,Q,R,S,T,U,V,W,Y # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 NE2 ? A HIS 302 ? A HIS 304 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 NA ? L N7H . ? A N7H 1458 ? 1_555 83.9 ? 2 NE2 ? A HIS 302 ? A HIS 304 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 NB ? L N7H . ? A N7H 1458 ? 1_555 91.3 ? 3 NA ? L N7H . ? A N7H 1458 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 NB ? L N7H . ? A N7H 1458 ? 1_555 90.2 ? 4 NE2 ? A HIS 302 ? A HIS 304 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 NC ? L N7H . ? A N7H 1458 ? 1_555 96.4 ? 5 NA ? L N7H . ? A N7H 1458 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 NC ? L N7H . ? A N7H 1458 ? 1_555 178.8 ? 6 NB ? L N7H . ? A N7H 1458 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 NC ? L N7H . ? A N7H 1458 ? 1_555 88.7 ? 7 NE2 ? A HIS 302 ? A HIS 304 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 ND ? L N7H . ? A N7H 1458 ? 1_555 89.5 ? 8 NA ? L N7H . ? A N7H 1458 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 ND ? L N7H . ? A N7H 1458 ? 1_555 90.3 ? 9 NB ? L N7H . ? A N7H 1458 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 ND ? L N7H . ? A N7H 1458 ? 1_555 179.0 ? 10 NC ? L N7H . ? A N7H 1458 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 ND ? L N7H . ? A N7H 1458 ? 1_555 90.8 ? 11 NE2 ? A HIS 302 ? A HIS 304 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 O1 ? N NO2 . ? A NO2 1460 ? 1_555 174.2 ? 12 NA ? L N7H . ? A N7H 1458 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 O1 ? N NO2 . ? A NO2 1460 ? 1_555 93.0 ? 13 NB ? L N7H . ? A N7H 1458 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 O1 ? N NO2 . ? A NO2 1460 ? 1_555 83.9 ? 14 NC ? L N7H . ? A N7H 1458 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 O1 ? N NO2 . ? A NO2 1460 ? 1_555 86.6 ? 15 ND ? L N7H . ? A N7H 1458 ? 1_555 FE ? L N7H . ? A N7H 1458 ? 1_555 O1 ? N NO2 . ? A NO2 1460 ? 1_555 95.3 ? 16 NE2 ? B HIS 302 ? B HIS 304 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 NA ? V N7H . ? B N7H 1456 ? 1_555 85.9 ? 17 NE2 ? B HIS 302 ? B HIS 304 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 NB ? V N7H . ? B N7H 1456 ? 1_555 92.0 ? 18 NA ? V N7H . ? B N7H 1456 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 NB ? V N7H . ? B N7H 1456 ? 1_555 90.3 ? 19 NE2 ? B HIS 302 ? B HIS 304 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 NC ? V N7H . ? B N7H 1456 ? 1_555 94.4 ? 20 NA ? V N7H . ? B N7H 1456 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 NC ? V N7H . ? B N7H 1456 ? 1_555 178.8 ? 21 NB ? V N7H . ? B N7H 1456 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 NC ? V N7H . ? B N7H 1456 ? 1_555 88.5 ? 22 NE2 ? B HIS 302 ? B HIS 304 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 ND ? V N7H . ? B N7H 1456 ? 1_555 88.8 ? 23 NA ? V N7H . ? B N7H 1456 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 ND ? V N7H . ? B N7H 1456 ? 1_555 90.4 ? 24 NB ? V N7H . ? B N7H 1456 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 ND ? V N7H . ? B N7H 1456 ? 1_555 179.0 ? 25 NC ? V N7H . ? B N7H 1456 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 ND ? V N7H . ? B N7H 1456 ? 1_555 90.8 ? 26 NE2 ? B HIS 302 ? B HIS 304 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 O1 ? W NO2 . ? B NO2 1457 ? 1_555 174.2 ? 27 NA ? V N7H . ? B N7H 1456 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 O1 ? W NO2 . ? B NO2 1457 ? 1_555 90.7 ? 28 NB ? V N7H . ? B N7H 1456 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 O1 ? W NO2 . ? B NO2 1457 ? 1_555 83.2 ? 29 NC ? V N7H . ? B N7H 1456 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 O1 ? W NO2 . ? B NO2 1457 ? 1_555 88.9 ? 30 ND ? V N7H . ? B N7H 1456 ? 1_555 FE ? V N7H . ? B N7H 1456 ? 1_555 O1 ? W NO2 . ? B NO2 1457 ? 1_555 96.0 ? # _pdbx_audit_revision_history.ordinal 1 _pdbx_audit_revision_history.data_content_type 'Structure model' _pdbx_audit_revision_history.major_revision 1 _pdbx_audit_revision_history.minor_revision 0 _pdbx_audit_revision_history.revision_date 2016-03-02 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal REFMAC refinement 5.8.0073 ? 1 XDS 'data reduction' . ? 2 XDS 'data scaling' . ? 3 PHASER phasing . ? 4 # _pdbx_entry_details.entry_id 5AG1 _pdbx_entry_details.compound_details ? _pdbx_entry_details.source_details ? _pdbx_entry_details.nonpolymer_details ;DELTA-MESO NITROHEME (N7H): IRON PROTOPORPHYRIN IX WITH A NITRO GROUP AT THE DELTA-MESO CARBON. ; _pdbx_entry_details.sequence_details 'PRECURSOR SEQUENCE IN GENBANK WITH PROLONGED N-TERMINUS.' # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 O A HOH 2306 ? ? O A HOH 2418 ? ? 2.12 2 1 O B ALA 288 ? ? O B HOH 2313 ? ? 2.14 3 1 OG1 A THR 96 ? B O A HOH 2167 ? ? 2.19 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 TYR A 285 ? ? 89.01 -9.48 2 1 ARG A 311 ? ? 49.49 -125.16 3 1 TRP A 377 ? ? -109.18 -65.08 4 1 PHE B 178 ? ? -122.23 -53.01 5 1 THR B 265 ? ? -155.64 81.66 6 1 TYR B 285 ? ? 88.66 -6.23 7 1 ARG B 311 ? ? 51.24 -122.14 8 1 TRP B 377 ? ? -109.96 -65.10 9 1 ASN B 415 ? ? -158.55 79.79 # loop_ _pdbx_validate_chiral.id _pdbx_validate_chiral.PDB_model_num _pdbx_validate_chiral.auth_atom_id _pdbx_validate_chiral.label_alt_id _pdbx_validate_chiral.auth_asym_id _pdbx_validate_chiral.auth_comp_id _pdbx_validate_chiral.auth_seq_id _pdbx_validate_chiral.PDB_ins_code _pdbx_validate_chiral.details _pdbx_validate_chiral.omega 1 1 NA ? A N7H 1458 ? PLANAR . 2 1 NB ? A N7H 1458 ? PLANAR . 3 1 ND ? A N7H 1458 ? PLANAR . 4 1 NA ? B N7H 1456 ? PLANAR . 5 1 NB ? B N7H 1456 ? PLANAR . 6 1 ND ? B N7H 1456 ? PLANAR . # loop_ _pdbx_distant_solvent_atoms.id _pdbx_distant_solvent_atoms.PDB_model_num _pdbx_distant_solvent_atoms.auth_atom_id _pdbx_distant_solvent_atoms.label_alt_id _pdbx_distant_solvent_atoms.auth_asym_id _pdbx_distant_solvent_atoms.auth_comp_id _pdbx_distant_solvent_atoms.auth_seq_id _pdbx_distant_solvent_atoms.PDB_ins_code _pdbx_distant_solvent_atoms.neighbor_macromolecule_distance _pdbx_distant_solvent_atoms.neighbor_ligand_distance 1 1 O ? A HOH 2004 ? 6.22 . 2 1 O ? A HOH 2248 ? 5.82 . 3 1 O ? B HOH 2138 ? 6.34 . 4 1 O ? B HOH 2410 ? 5.85 . # _pdbx_unobs_or_zero_occ_residues.id 1 _pdbx_unobs_or_zero_occ_residues.PDB_model_num 1 _pdbx_unobs_or_zero_occ_residues.polymer_flag Y _pdbx_unobs_or_zero_occ_residues.occupancy_flag 1 _pdbx_unobs_or_zero_occ_residues.auth_asym_id B _pdbx_unobs_or_zero_occ_residues.auth_comp_id SER _pdbx_unobs_or_zero_occ_residues.auth_seq_id 3 _pdbx_unobs_or_zero_occ_residues.PDB_ins_code ? _pdbx_unobs_or_zero_occ_residues.label_asym_id B _pdbx_unobs_or_zero_occ_residues.label_comp_id SER _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 'CACODYLATE ION' CAC 3 GLYCEROL GOL 4 N-ACETYL-D-GLUCOSAMINE NAG 5 'DELTA-MESO NITROHEME' N7H 6 'FORMIC ACID' FMT 7 'NITRITE ION' NO2 8 water HOH #