data_4YIZ # _entry.id 4YIZ # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.286 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4YIZ WWPDB D_1000207544 # _pdbx_database_related.content_type unspecified _pdbx_database_related.db_id 4YIV _pdbx_database_related.db_name PDB _pdbx_database_related.details . # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 4YIZ _pdbx_database_status.recvd_initial_deposition_date 2015-03-02 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Parker, M.L.' 1 'Boulanger, M.J.' 2 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country US _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'Plos One' _citation.journal_id_ASTM ? _citation.journal_id_CSD ? _citation.journal_id_ISSN 1932-6203 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 10 _citation.language ? _citation.page_first e0126206 _citation.page_last e0126206 _citation.title 'An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity.' _citation.year 2015 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1371/journal.pone.0126206 _citation.pdbx_database_id_PubMed 25955165 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Parker, M.L.' 1 primary 'Boulanger, M.J.' 2 # _cell.entry_id 4YIZ _cell.length_a 265.928 _cell.length_b 265.928 _cell.length_c 94.160 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 120.00 _cell.Z_PDB 18 _cell.pdbx_unique_axis ? # _symmetry.entry_id 4YIZ _symmetry.space_group_name_H-M 'P 32 2 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 154 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Apical membrane antigen AMA1' 46064.297 3 ? ? 'residues 64-484' ? 2 polymer man 'Rhoptry neck protein 2, putative' 3872.359 3 ? ? 'residues 1261-1285' ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 3 ? ? ? ? 4 non-polymer man N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE 221.208 1 ? ? ? ? 5 non-polymer syn 'SULFATE ION' 96.063 5 ? ? ? ? 6 water nat water 18.015 487 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;GSAMGSASTSGNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNF LEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFV YDSKKRLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGV WKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPGSGSGSGDQPHSGGVGRNYGFYYVDTTGEGKCALSDQVP DCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQIQSTSVDC TADEQNECGSNTAAALVPR ; ;GSAMGSASTSGNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNF LEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFV YDSKKRLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGV WKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPGSGSGSGDQPHSGGVGRNYGFYYVDTTGEGKCALSDQVP DCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQIQSTSVDC TADEQNECGSNTAAALVPR ; A,C,E ? 2 'polypeptide(L)' no no GSASDITQHLNDSGLGPAVECLENLVVGPVCPAAVVAPAV GSASDITQHLNDSGLGPAVECLENLVVGPVCPAAVVAPAV B,D,F ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLY n 1 2 SER n 1 3 ALA n 1 4 MET n 1 5 GLY n 1 6 SER n 1 7 ALA n 1 8 SER n 1 9 THR n 1 10 SER n 1 11 GLY n 1 12 ASN n 1 13 PRO n 1 14 PHE n 1 15 GLN n 1 16 ALA n 1 17 ASN n 1 18 VAL n 1 19 GLU n 1 20 MET n 1 21 LYS n 1 22 THR n 1 23 PHE n 1 24 MET n 1 25 GLU n 1 26 ARG n 1 27 PHE n 1 28 ASN n 1 29 LEU n 1 30 THR n 1 31 HIS n 1 32 HIS n 1 33 HIS n 1 34 GLN n 1 35 SER n 1 36 GLY n 1 37 ILE n 1 38 TYR n 1 39 VAL n 1 40 ASP n 1 41 LEU n 1 42 GLY n 1 43 GLN n 1 44 ASP n 1 45 LYS n 1 46 GLU n 1 47 VAL n 1 48 ASP n 1 49 GLY n 1 50 THR n 1 51 LEU n 1 52 TYR n 1 53 ARG n 1 54 GLU n 1 55 PRO n 1 56 ALA n 1 57 GLY n 1 58 LEU n 1 59 CYS n 1 60 PRO n 1 61 ILE n 1 62 TRP n 1 63 GLY n 1 64 LYS n 1 65 HIS n 1 66 ILE n 1 67 GLU n 1 68 LEU n 1 69 GLN n 1 70 GLN n 1 71 PRO n 1 72 ASP n 1 73 ARG n 1 74 PRO n 1 75 PRO n 1 76 TYR n 1 77 ARG n 1 78 ASN n 1 79 ASN n 1 80 PHE n 1 81 LEU n 1 82 GLU n 1 83 ASP n 1 84 VAL n 1 85 PRO n 1 86 THR n 1 87 GLU n 1 88 LYS n 1 89 GLU n 1 90 TYR n 1 91 LYS n 1 92 GLN n 1 93 SER n 1 94 GLY n 1 95 ASN n 1 96 PRO n 1 97 LEU n 1 98 PRO n 1 99 GLY n 1 100 GLY n 1 101 PHE n 1 102 ASN n 1 103 LEU n 1 104 ASN n 1 105 PHE n 1 106 VAL n 1 107 THR n 1 108 PRO n 1 109 SER n 1 110 GLY n 1 111 GLN n 1 112 ARG n 1 113 ILE n 1 114 SER n 1 115 PRO n 1 116 PHE n 1 117 PRO n 1 118 MET n 1 119 GLU n 1 120 LEU n 1 121 LEU n 1 122 GLU n 1 123 LYS n 1 124 ASN n 1 125 SER n 1 126 ASN n 1 127 ILE n 1 128 LYS n 1 129 ALA n 1 130 SER n 1 131 THR n 1 132 ASP n 1 133 LEU n 1 134 GLY n 1 135 ARG n 1 136 CYS n 1 137 ALA n 1 138 GLU n 1 139 PHE n 1 140 ALA n 1 141 PHE n 1 142 LYS n 1 143 THR n 1 144 VAL n 1 145 ALA n 1 146 MET n 1 147 ASP n 1 148 LYS n 1 149 ASN n 1 150 ASN n 1 151 LYS n 1 152 ALA n 1 153 THR n 1 154 LYS n 1 155 TYR n 1 156 ARG n 1 157 TYR n 1 158 PRO n 1 159 PHE n 1 160 VAL n 1 161 TYR n 1 162 ASP n 1 163 SER n 1 164 LYS n 1 165 LYS n 1 166 ARG n 1 167 LEU n 1 168 CYS n 1 169 HIS n 1 170 ILE n 1 171 LEU n 1 172 TYR n 1 173 VAL n 1 174 SER n 1 175 MET n 1 176 GLN n 1 177 LEU n 1 178 MET n 1 179 GLU n 1 180 GLY n 1 181 LYS n 1 182 LYS n 1 183 TYR n 1 184 CYS n 1 185 SER n 1 186 VAL n 1 187 LYS n 1 188 GLY n 1 189 GLU n 1 190 PRO n 1 191 PRO n 1 192 ASP n 1 193 LEU n 1 194 THR n 1 195 TRP n 1 196 TYR n 1 197 CYS n 1 198 PHE n 1 199 LYS n 1 200 PRO n 1 201 ARG n 1 202 LYS n 1 203 SER n 1 204 VAL n 1 205 THR n 1 206 GLU n 1 207 ASN n 1 208 HIS n 1 209 HIS n 1 210 LEU n 1 211 ILE n 1 212 TYR n 1 213 GLY n 1 214 SER n 1 215 ALA n 1 216 TYR n 1 217 VAL n 1 218 GLY n 1 219 GLU n 1 220 ASN n 1 221 PRO n 1 222 ASP n 1 223 ALA n 1 224 PHE n 1 225 ILE n 1 226 SER n 1 227 LYS n 1 228 CYS n 1 229 PRO n 1 230 ASN n 1 231 GLN n 1 232 ALA n 1 233 LEU n 1 234 ARG n 1 235 GLY n 1 236 TYR n 1 237 ARG n 1 238 PHE n 1 239 GLY n 1 240 VAL n 1 241 TRP n 1 242 LYS n 1 243 LYS n 1 244 GLY n 1 245 ARG n 1 246 CYS n 1 247 LEU n 1 248 ASP n 1 249 TYR n 1 250 THR n 1 251 GLU n 1 252 LEU n 1 253 THR n 1 254 ASP n 1 255 THR n 1 256 VAL n 1 257 ILE n 1 258 GLU n 1 259 ARG n 1 260 VAL n 1 261 GLU n 1 262 SER n 1 263 LYS n 1 264 ALA n 1 265 GLN n 1 266 CYS n 1 267 TRP n 1 268 VAL n 1 269 LYS n 1 270 THR n 1 271 PHE n 1 272 GLU n 1 273 ASN n 1 274 ASP n 1 275 GLY n 1 276 VAL n 1 277 ALA n 1 278 SER n 1 279 ASP n 1 280 GLN n 1 281 PRO n 1 282 GLY n 1 283 SER n 1 284 GLY n 1 285 SER n 1 286 GLY n 1 287 SER n 1 288 GLY n 1 289 ASP n 1 290 GLN n 1 291 PRO n 1 292 HIS n 1 293 SER n 1 294 GLY n 1 295 GLY n 1 296 VAL n 1 297 GLY n 1 298 ARG n 1 299 ASN n 1 300 TYR n 1 301 GLY n 1 302 PHE n 1 303 TYR n 1 304 TYR n 1 305 VAL n 1 306 ASP n 1 307 THR n 1 308 THR n 1 309 GLY n 1 310 GLU n 1 311 GLY n 1 312 LYS n 1 313 CYS n 1 314 ALA n 1 315 LEU n 1 316 SER n 1 317 ASP n 1 318 GLN n 1 319 VAL n 1 320 PRO n 1 321 ASP n 1 322 CYS n 1 323 LEU n 1 324 VAL n 1 325 SER n 1 326 ASP n 1 327 SER n 1 328 ALA n 1 329 ALA n 1 330 VAL n 1 331 SER n 1 332 TYR n 1 333 THR n 1 334 ALA n 1 335 ALA n 1 336 GLY n 1 337 SER n 1 338 LEU n 1 339 SER n 1 340 GLU n 1 341 GLU n 1 342 THR n 1 343 PRO n 1 344 ASN n 1 345 PHE n 1 346 ILE n 1 347 ILE n 1 348 PRO n 1 349 SER n 1 350 ASN n 1 351 PRO n 1 352 SER n 1 353 VAL n 1 354 THR n 1 355 PRO n 1 356 PRO n 1 357 THR n 1 358 PRO n 1 359 GLU n 1 360 THR n 1 361 ALA n 1 362 LEU n 1 363 GLN n 1 364 CYS n 1 365 THR n 1 366 ALA n 1 367 ASP n 1 368 LYS n 1 369 PHE n 1 370 PRO n 1 371 ASP n 1 372 SER n 1 373 PHE n 1 374 GLY n 1 375 ALA n 1 376 CYS n 1 377 ASP n 1 378 VAL n 1 379 GLN n 1 380 ALA n 1 381 CYS n 1 382 LYS n 1 383 ARG n 1 384 GLN n 1 385 LYS n 1 386 THR n 1 387 SER n 1 388 CYS n 1 389 VAL n 1 390 GLY n 1 391 GLY n 1 392 GLN n 1 393 ILE n 1 394 GLN n 1 395 SER n 1 396 THR n 1 397 SER n 1 398 VAL n 1 399 ASP n 1 400 CYS n 1 401 THR n 1 402 ALA n 1 403 ASP n 1 404 GLU n 1 405 GLN n 1 406 ASN n 1 407 GLU n 1 408 CYS n 1 409 GLY n 1 410 SER n 1 411 ASN n 1 412 THR n 1 413 ALA n 1 414 ALA n 1 415 ALA n 1 416 LEU n 1 417 VAL n 1 418 PRO n 1 419 ARG n 2 1 GLY n 2 2 SER n 2 3 ALA n 2 4 SER n 2 5 ASP n 2 6 ILE n 2 7 THR n 2 8 GLN n 2 9 HIS n 2 10 LEU n 2 11 ASN n 2 12 ASP n 2 13 SER n 2 14 GLY n 2 15 LEU n 2 16 GLY n 2 17 PRO n 2 18 ALA n 2 19 VAL n 2 20 GLU n 2 21 CYS n 2 22 LEU n 2 23 GLU n 2 24 ASN n 2 25 LEU n 2 26 VAL n 2 27 VAL n 2 28 GLY n 2 29 PRO n 2 30 VAL n 2 31 CYS n 2 32 PRO n 2 33 ALA n 2 34 ALA n 2 35 VAL n 2 36 VAL n 2 37 ALA n 2 38 PRO n 2 39 ALA n 2 40 VAL n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample 'Biological sequence' 1 419 ? ? TGME49_255260 ? ? ? ? ? ? 'Toxoplasma gondii ME49' 508771 ? ? ? ? ? ? ? 'Cabbage Looper' 'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? Baculovirus pAcGP67b ? ? ? ? ? 2 1 sample 'Biological sequence' 1 40 'Coccidian parasite' ? ETH_00012760 ? ? ? ? ? ? 'Eimeria tenella' 5802 ? ? ? ? ? ? ? ? 'Escherichia coli' 469008 ? ? ? ? ? ? 'BL21(DE3)' ? ? ? ? ? ? ? plasmid ? ? ? pET32a ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin 1 UNP S8GKS3_TOXGO S8GKS3 ? 1 ;SASTSGNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVP TEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKK RLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGR CLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPHTYPLTSQASWNDWWPLHQSDQPHSGGVGRNYGFYYVDTTGEGK CALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQ IQSTSVDCTADEQNECGSNTA ; 64 2 UNP U6KQJ2_EIMTE U6KQJ2 ? 2 SDITQHLNDSGLGPAVECLENLVVGPVCPAAVVAPAV 1261 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4YIZ A 6 ? 413 ? S8GKS3 64 ? 484 ? 64 484 2 1 4YIZ C 6 ? 413 ? S8GKS3 64 ? 484 ? 64 484 3 1 4YIZ E 6 ? 413 ? S8GKS3 64 ? 484 ? 64 484 4 2 4YIZ B 4 ? 40 ? U6KQJ2 1261 ? 1297 ? 1261 1297 5 2 4YIZ D 4 ? 40 ? U6KQJ2 1261 ? 1297 ? 1261 1297 6 2 4YIZ F 4 ? 40 ? U6KQJ2 1261 ? 1297 ? 1261 1297 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 4YIZ GLY A 1 ? UNP S8GKS3 ? ? 'expression tag' 59 1 1 4YIZ SER A 2 ? UNP S8GKS3 ? ? 'expression tag' 60 2 1 4YIZ ALA A 3 ? UNP S8GKS3 ? ? 'expression tag' 61 3 1 4YIZ MET A 4 ? UNP S8GKS3 ? ? 'expression tag' 62 4 1 4YIZ GLY A 5 ? UNP S8GKS3 ? ? 'expression tag' 63 5 1 4YIZ ? A ? ? UNP S8GKS3 HIS 340 deletion ? 6 1 4YIZ ? A ? ? UNP S8GKS3 THR 341 deletion ? 7 1 4YIZ ? A ? ? UNP S8GKS3 TYR 342 deletion ? 8 1 4YIZ ? A ? ? UNP S8GKS3 PRO 343 deletion ? 9 1 4YIZ ? A ? ? UNP S8GKS3 LEU 344 deletion ? 10 1 4YIZ ? A ? ? UNP S8GKS3 THR 345 deletion ? 11 1 4YIZ ? A ? ? UNP S8GKS3 SER 346 deletion ? 12 1 4YIZ ? A ? ? UNP S8GKS3 GLN 347 deletion ? 13 1 4YIZ ? A ? ? UNP S8GKS3 ALA 348 deletion ? 14 1 4YIZ ? A ? ? UNP S8GKS3 SER 349 deletion ? 15 1 4YIZ ? A ? ? UNP S8GKS3 TRP 350 deletion ? 16 1 4YIZ ? A ? ? UNP S8GKS3 ASN 351 deletion ? 17 1 4YIZ ? A ? ? UNP S8GKS3 ASP 352 deletion ? 18 1 4YIZ GLY A 282 ? UNP S8GKS3 TRP 353 linker 353 19 1 4YIZ SER A 283 ? UNP S8GKS3 TRP 354 linker 354 20 1 4YIZ GLY A 284 ? UNP S8GKS3 PRO 355 linker 355 21 1 4YIZ SER A 285 ? UNP S8GKS3 LEU 356 linker 356 22 1 4YIZ GLY A 286 ? UNP S8GKS3 HIS 357 linker 357 23 1 4YIZ SER A 287 ? UNP S8GKS3 GLN 358 linker 358 24 1 4YIZ GLY A 288 ? UNP S8GKS3 SER 359 linker 359 25 1 4YIZ ALA A 414 ? UNP S8GKS3 ? ? 'expression tag' 485 26 1 4YIZ ALA A 415 ? UNP S8GKS3 ? ? 'expression tag' 486 27 1 4YIZ LEU A 416 ? UNP S8GKS3 ? ? 'expression tag' 487 28 1 4YIZ VAL A 417 ? UNP S8GKS3 ? ? 'expression tag' 488 29 1 4YIZ PRO A 418 ? UNP S8GKS3 ? ? 'expression tag' 489 30 1 4YIZ ARG A 419 ? UNP S8GKS3 ? ? 'expression tag' 490 31 2 4YIZ GLY C 1 ? UNP S8GKS3 ? ? 'expression tag' 59 32 2 4YIZ SER C 2 ? UNP S8GKS3 ? ? 'expression tag' 60 33 2 4YIZ ALA C 3 ? UNP S8GKS3 ? ? 'expression tag' 61 34 2 4YIZ MET C 4 ? UNP S8GKS3 ? ? 'expression tag' 62 35 2 4YIZ GLY C 5 ? UNP S8GKS3 ? ? 'expression tag' 63 36 2 4YIZ ? C ? ? UNP S8GKS3 HIS 340 deletion ? 37 2 4YIZ ? C ? ? UNP S8GKS3 THR 341 deletion ? 38 2 4YIZ ? C ? ? UNP S8GKS3 TYR 342 deletion ? 39 2 4YIZ ? C ? ? UNP S8GKS3 PRO 343 deletion ? 40 2 4YIZ ? C ? ? UNP S8GKS3 LEU 344 deletion ? 41 2 4YIZ ? C ? ? UNP S8GKS3 THR 345 deletion ? 42 2 4YIZ ? C ? ? UNP S8GKS3 SER 346 deletion ? 43 2 4YIZ ? C ? ? UNP S8GKS3 GLN 347 deletion ? 44 2 4YIZ ? C ? ? UNP S8GKS3 ALA 348 deletion ? 45 2 4YIZ ? C ? ? UNP S8GKS3 SER 349 deletion ? 46 2 4YIZ ? C ? ? UNP S8GKS3 TRP 350 deletion ? 47 2 4YIZ ? C ? ? UNP S8GKS3 ASN 351 deletion ? 48 2 4YIZ ? C ? ? UNP S8GKS3 ASP 352 deletion ? 49 2 4YIZ GLY C 282 ? UNP S8GKS3 TRP 353 linker 353 50 2 4YIZ SER C 283 ? UNP S8GKS3 TRP 354 linker 354 51 2 4YIZ GLY C 284 ? UNP S8GKS3 PRO 355 linker 355 52 2 4YIZ SER C 285 ? UNP S8GKS3 LEU 356 linker 356 53 2 4YIZ GLY C 286 ? UNP S8GKS3 HIS 357 linker 357 54 2 4YIZ SER C 287 ? UNP S8GKS3 GLN 358 linker 358 55 2 4YIZ GLY C 288 ? UNP S8GKS3 SER 359 linker 359 56 2 4YIZ ALA C 414 ? UNP S8GKS3 ? ? 'expression tag' 485 57 2 4YIZ ALA C 415 ? UNP S8GKS3 ? ? 'expression tag' 486 58 2 4YIZ LEU C 416 ? UNP S8GKS3 ? ? 'expression tag' 487 59 2 4YIZ VAL C 417 ? UNP S8GKS3 ? ? 'expression tag' 488 60 2 4YIZ PRO C 418 ? UNP S8GKS3 ? ? 'expression tag' 489 61 2 4YIZ ARG C 419 ? UNP S8GKS3 ? ? 'expression tag' 490 62 3 4YIZ GLY E 1 ? UNP S8GKS3 ? ? 'expression tag' 59 63 3 4YIZ SER E 2 ? UNP S8GKS3 ? ? 'expression tag' 60 64 3 4YIZ ALA E 3 ? UNP S8GKS3 ? ? 'expression tag' 61 65 3 4YIZ MET E 4 ? UNP S8GKS3 ? ? 'expression tag' 62 66 3 4YIZ GLY E 5 ? UNP S8GKS3 ? ? 'expression tag' 63 67 3 4YIZ ? E ? ? UNP S8GKS3 HIS 340 deletion ? 68 3 4YIZ ? E ? ? UNP S8GKS3 THR 341 deletion ? 69 3 4YIZ ? E ? ? UNP S8GKS3 TYR 342 deletion ? 70 3 4YIZ ? E ? ? UNP S8GKS3 PRO 343 deletion ? 71 3 4YIZ ? E ? ? UNP S8GKS3 LEU 344 deletion ? 72 3 4YIZ ? E ? ? UNP S8GKS3 THR 345 deletion ? 73 3 4YIZ ? E ? ? UNP S8GKS3 SER 346 deletion ? 74 3 4YIZ ? E ? ? UNP S8GKS3 GLN 347 deletion ? 75 3 4YIZ ? E ? ? UNP S8GKS3 ALA 348 deletion ? 76 3 4YIZ ? E ? ? UNP S8GKS3 SER 349 deletion ? 77 3 4YIZ ? E ? ? UNP S8GKS3 TRP 350 deletion ? 78 3 4YIZ ? E ? ? UNP S8GKS3 ASN 351 deletion ? 79 3 4YIZ ? E ? ? UNP S8GKS3 ASP 352 deletion ? 80 3 4YIZ GLY E 282 ? UNP S8GKS3 TRP 353 linker 353 81 3 4YIZ SER E 283 ? UNP S8GKS3 TRP 354 linker 354 82 3 4YIZ GLY E 284 ? UNP S8GKS3 PRO 355 linker 355 83 3 4YIZ SER E 285 ? UNP S8GKS3 LEU 356 linker 356 84 3 4YIZ GLY E 286 ? UNP S8GKS3 HIS 357 linker 357 85 3 4YIZ SER E 287 ? UNP S8GKS3 GLN 358 linker 358 86 3 4YIZ GLY E 288 ? UNP S8GKS3 SER 359 linker 359 87 3 4YIZ ALA E 414 ? UNP S8GKS3 ? ? 'expression tag' 485 88 3 4YIZ ALA E 415 ? UNP S8GKS3 ? ? 'expression tag' 486 89 3 4YIZ LEU E 416 ? UNP S8GKS3 ? ? 'expression tag' 487 90 3 4YIZ VAL E 417 ? UNP S8GKS3 ? ? 'expression tag' 488 91 3 4YIZ PRO E 418 ? UNP S8GKS3 ? ? 'expression tag' 489 92 3 4YIZ ARG E 419 ? UNP S8GKS3 ? ? 'expression tag' 490 93 4 4YIZ GLY B 1 ? UNP U6KQJ2 ? ? 'expression tag' 1258 94 4 4YIZ SER B 2 ? UNP U6KQJ2 ? ? 'expression tag' 1259 95 4 4YIZ ALA B 3 ? UNP U6KQJ2 ? ? 'expression tag' 1260 96 5 4YIZ GLY D 1 ? UNP U6KQJ2 ? ? 'expression tag' 1258 97 5 4YIZ SER D 2 ? UNP U6KQJ2 ? ? 'expression tag' 1259 98 5 4YIZ ALA D 3 ? UNP U6KQJ2 ? ? 'expression tag' 1260 99 6 4YIZ GLY F 1 ? UNP U6KQJ2 ? ? 'expression tag' 1258 100 6 4YIZ SER F 2 ? UNP U6KQJ2 ? ? 'expression tag' 1259 101 6 4YIZ ALA F 3 ? UNP U6KQJ2 ? ? 'expression tag' 1260 102 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight A2G saccharide . N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE ? 'C8 H15 N O6' 221.208 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 4YIZ _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 6.42 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 80.9 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH 5.0 _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 291 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '0.1 M tri-sodium citrate pH 5.0 and 2.0 M ammonium sulfate' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector PIXEL _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'DECTRIS PILATUS 6M' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2013-04-18 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator 'Liquid nitrogen-cooled double crystal, non fixed exit slit' _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9795 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'SSRL BEAMLINE BL12-2' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 0.9795 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline BL12-2 _diffrn_source.pdbx_synchrotron_site SSRL # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 4YIZ _reflns.observed_criterion_sigma_I ? _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 72.890 _reflns.d_resolution_high 2.200 _reflns.number_obs 180412 _reflns.number_all ? _reflns.percent_possible_obs 93.9 _reflns.pdbx_Rmerge_I_obs 0.13300 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 6.6000 _reflns.B_iso_Wilson_estimate 23.00 _reflns.pdbx_redundancy 4.300 # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 2.20 _reflns_shell.d_res_low 2.32 _reflns_shell.percent_possible_all 94.4 _reflns_shell.Rmerge_I_obs 0.47500 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 3.400 _reflns_shell.pdbx_redundancy 4.30 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 4YIZ _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 179956 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.340 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 59.50 _refine.ls_d_res_high 2.20 _refine.ls_percent_reflns_obs 93.5 _refine.ls_R_factor_obs 0.188 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.187 _refine.ls_R_factor_R_free 0.207 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.030 _refine.ls_number_reflns_R_free 9059 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean 34.95 _refine.aniso_B[1][1] ? _refine.aniso_B[2][2] ? _refine.aniso_B[3][3] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][3] ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_ls_cross_valid_method 'FREE R-VALUE' _refine.details ? _refine.pdbx_starting_model 'PDB ID 2Y8T' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details 'Random selection' _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.210 _refine.pdbx_overall_phase_error 20.410 _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 9975 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 81 _refine_hist.number_atoms_solvent 487 _refine_hist.number_atoms_total 10543 _refine_hist.d_res_high 2.20 _refine_hist.d_res_low 59.50 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function f_bond_d 0.003 ? ? 10421 'X-RAY DIFFRACTION' ? f_angle_d 0.845 ? ? 14134 'X-RAY DIFFRACTION' ? f_dihedral_angle_d 14.380 ? ? 3858 'X-RAY DIFFRACTION' ? f_chiral_restr 0.032 ? ? 1515 'X-RAY DIFFRACTION' ? f_plane_restr 0.003 ? ? 1880 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_all _refine_ls_shell.R_factor_all 'X-RAY DIFFRACTION' . 2.2000 2.2250 5676 0.2368 94.00 0.2342 . . 305 . . 'X-RAY DIFFRACTION' . 2.2250 2.2512 5632 0.3600 92.00 0.3619 . . 267 . . 'X-RAY DIFFRACTION' . 2.2512 2.2787 5697 0.2694 94.00 0.2874 . . 305 . . 'X-RAY DIFFRACTION' . 2.2787 2.3075 5593 0.2188 92.00 0.2462 . . 318 . . 'X-RAY DIFFRACTION' . 2.3075 2.3379 5720 0.2184 94.00 0.2395 . . 276 . . 'X-RAY DIFFRACTION' . 2.3379 2.3699 5779 0.2181 95.00 0.2660 . . 326 . . 'X-RAY DIFFRACTION' . 2.3699 2.4038 5831 0.2107 96.00 0.2495 . . 259 . . 'X-RAY DIFFRACTION' . 2.4038 2.4396 5849 0.2026 96.00 0.2271 . . 319 . . 'X-RAY DIFFRACTION' . 2.4396 2.4778 5775 0.1993 95.00 0.2133 . . 324 . . 'X-RAY DIFFRACTION' . 2.4778 2.5184 5727 0.2079 95.00 0.2377 . . 308 . . 'X-RAY DIFFRACTION' . 2.5184 2.5618 5633 0.2116 92.00 0.2452 . . 290 . . 'X-RAY DIFFRACTION' . 2.5618 2.6084 5554 0.2120 92.00 0.2427 . . 319 . . 'X-RAY DIFFRACTION' . 2.6084 2.6586 5022 0.2124 83.00 0.2457 . . 265 . . 'X-RAY DIFFRACTION' . 2.6586 2.7128 5653 0.2167 93.00 0.2342 . . 300 . . 'X-RAY DIFFRACTION' . 2.7128 2.7718 5910 0.2040 97.00 0.2046 . . 306 . . 'X-RAY DIFFRACTION' . 2.7718 2.8363 5892 0.2102 97.00 0.2345 . . 291 . . 'X-RAY DIFFRACTION' . 2.8363 2.9072 5698 0.2113 94.00 0.2343 . . 287 . . 'X-RAY DIFFRACTION' . 2.9072 2.9858 5795 0.2163 95.00 0.2442 . . 290 . . 'X-RAY DIFFRACTION' . 2.9858 3.0737 5828 0.2045 96.00 0.2299 . . 323 . . 'X-RAY DIFFRACTION' . 3.0737 3.1729 5802 0.1992 95.00 0.2420 . . 299 . . 'X-RAY DIFFRACTION' . 3.1729 3.2863 5824 0.1975 96.00 0.2243 . . 317 . . 'X-RAY DIFFRACTION' . 3.2863 3.4178 5404 0.1859 89.00 0.2272 . . 291 . . 'X-RAY DIFFRACTION' . 3.4178 3.5734 5475 0.1743 89.00 0.1933 . . 284 . . 'X-RAY DIFFRACTION' . 3.5734 3.7617 5962 0.1556 97.00 0.1695 . . 328 . . 'X-RAY DIFFRACTION' . 3.7617 3.9974 5742 0.1483 95.00 0.1696 . . 348 . . 'X-RAY DIFFRACTION' . 3.9974 4.3059 5880 0.1398 95.00 0.1517 . . 294 . . 'X-RAY DIFFRACTION' . 4.3059 4.7391 5788 0.1295 95.00 0.1428 . . 328 . . 'X-RAY DIFFRACTION' . 4.7391 5.4245 5185 0.1460 84.00 0.1640 . . 265 . . 'X-RAY DIFFRACTION' . 5.4245 6.8327 5925 0.1644 96.00 0.1945 . . 304 . . 'X-RAY DIFFRACTION' . 6.8327 59.5205 5646 0.1901 90.00 0.1891 . . 323 . . # _struct.entry_id 4YIZ _struct.title 'Crystal structure of engineered TgAMA1 lacking the DII loop in complex with an Eimeria tenella RON2D3 peptide' _struct.pdbx_descriptor 'Apical membrane antigen AMA1' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 4YIZ _struct_keywords.text 'Apicomplexa, invasion, moving junction, parasite, protein engineering, PAN domain, IMMUNE SYSTEM' _struct_keywords.pdbx_keywords 'IMMUNE SYSTEM' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 1 ? D N N 2 ? E N N 2 ? F N N 2 ? G N N 3 ? H N N 4 ? I N N 5 ? J N N 5 ? K N N 3 ? L N N 5 ? M N N 5 ? N N N 3 ? O N N 5 ? P N N 6 ? Q N N 6 ? R N N 6 ? S N N 6 ? T N N 6 ? U N N 6 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 ASN A 12 ? ALA A 16 ? ASN A 70 ALA A 74 5 ? 5 HELX_P HELX_P2 AA2 ASN A 17 ? ARG A 26 ? ASN A 75 ARG A 84 1 ? 10 HELX_P HELX_P3 AA3 ASN A 28 ? HIS A 33 ? ASN A 86 HIS A 91 1 ? 6 HELX_P HELX_P4 AA4 THR A 86 ? GLY A 94 ? THR A 144 GLY A 152 1 ? 9 HELX_P HELX_P5 AA5 GLU A 119 ? LEU A 121 ? GLU A 177 LEU A 179 5 ? 3 HELX_P HELX_P6 AA6 THR A 131 ? LYS A 142 ? THR A 189 LYS A 200 1 ? 12 HELX_P HELX_P7 AA7 SER A 214 ? GLU A 219 ? SER A 272 GLU A 277 5 ? 6 HELX_P HELX_P8 AA8 ALA A 223 ? CYS A 228 ? ALA A 281 CYS A 286 1 ? 6 HELX_P HELX_P9 AA9 THR A 250 ? LEU A 252 ? THR A 308 LEU A 310 5 ? 3 HELX_P HELX_P10 AB1 SER A 262 ? ASN A 273 ? SER A 320 ASN A 331 1 ? 12 HELX_P HELX_P11 AB2 PRO A 343 ? ILE A 347 ? PRO A 414 ILE A 418 5 ? 5 HELX_P HELX_P12 AB3 ASN A 350 ? THR A 354 ? ASN A 421 THR A 425 5 ? 5 HELX_P HELX_P13 AB4 THR A 357 ? LEU A 362 ? THR A 428 LEU A 433 1 ? 6 HELX_P HELX_P14 AB5 ASP A 403 ? GLU A 407 ? ASP A 474 GLU A 478 5 ? 5 HELX_P HELX_P15 AB6 ASN B 12 ? ALA B 16 ? ASN C 70 ALA C 74 5 ? 5 HELX_P HELX_P16 AB7 ASN B 17 ? ARG B 26 ? ASN C 75 ARG C 84 1 ? 10 HELX_P HELX_P17 AB8 ASN B 28 ? HIS B 33 ? ASN C 86 HIS C 91 1 ? 6 HELX_P HELX_P18 AB9 THR B 86 ? GLY B 94 ? THR C 144 GLY C 152 1 ? 9 HELX_P HELX_P19 AC1 GLU B 119 ? LEU B 121 ? GLU C 177 LEU C 179 5 ? 3 HELX_P HELX_P20 AC2 THR B 131 ? LYS B 142 ? THR C 189 LYS C 200 1 ? 12 HELX_P HELX_P21 AC3 SER B 214 ? GLU B 219 ? SER C 272 GLU C 277 5 ? 6 HELX_P HELX_P22 AC4 ALA B 223 ? CYS B 228 ? ALA C 281 CYS C 286 1 ? 6 HELX_P HELX_P23 AC5 THR B 250 ? LEU B 252 ? THR C 308 LEU C 310 5 ? 3 HELX_P HELX_P24 AC6 SER B 262 ? ASN B 273 ? SER C 320 ASN C 331 1 ? 12 HELX_P HELX_P25 AC7 PRO B 343 ? ILE B 347 ? PRO C 414 ILE C 418 5 ? 5 HELX_P HELX_P26 AC8 ASN B 350 ? THR B 354 ? ASN C 421 THR C 425 5 ? 5 HELX_P HELX_P27 AC9 THR B 357 ? LEU B 362 ? THR C 428 LEU C 433 1 ? 6 HELX_P HELX_P28 AD1 ASP B 403 ? GLU B 407 ? ASP C 474 GLU C 478 5 ? 5 HELX_P HELX_P29 AD2 ASN C 12 ? ALA C 16 ? ASN E 70 ALA E 74 5 ? 5 HELX_P HELX_P30 AD3 ASN C 17 ? ARG C 26 ? ASN E 75 ARG E 84 1 ? 10 HELX_P HELX_P31 AD4 THR C 86 ? GLY C 94 ? THR E 144 GLY E 152 1 ? 9 HELX_P HELX_P32 AD5 MET C 118 ? GLU C 122 ? MET E 176 GLU E 180 1 ? 5 HELX_P HELX_P33 AD6 THR C 131 ? LYS C 142 ? THR E 189 LYS E 200 1 ? 12 HELX_P HELX_P34 AD7 SER C 214 ? GLU C 219 ? SER E 272 GLU E 277 5 ? 6 HELX_P HELX_P35 AD8 ALA C 223 ? CYS C 228 ? ALA E 281 CYS E 286 1 ? 6 HELX_P HELX_P36 AD9 THR C 250 ? LEU C 252 ? THR E 308 LEU E 310 5 ? 3 HELX_P HELX_P37 AE1 SER C 262 ? ASN C 273 ? SER E 320 ASN E 331 1 ? 12 HELX_P HELX_P38 AE2 PRO C 343 ? ILE C 347 ? PRO E 414 ILE E 418 5 ? 5 HELX_P HELX_P39 AE3 THR C 357 ? GLN C 363 ? THR E 428 GLN E 434 1 ? 7 HELX_P HELX_P40 AE4 ASP C 403 ? CYS C 408 ? ASP E 474 CYS E 479 5 ? 6 HELX_P HELX_P41 AE5 ALA D 3 ? SER D 13 ? ALA B 1260 SER B 1270 1 ? 11 HELX_P HELX_P42 AE6 ALA E 3 ? SER E 13 ? ALA D 1260 SER D 1270 1 ? 11 HELX_P HELX_P43 AE7 ALA F 3 ? SER F 13 ? ALA F 1260 SER F 1270 1 ? 11 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 59 SG ? ? ? 1_555 A CYS 228 SG ? ? A CYS 117 A CYS 286 1_555 ? ? ? ? ? ? ? 2.039 ? disulf2 disulf ? ? A CYS 136 SG ? ? ? 1_555 A CYS 168 SG ? ? A CYS 194 A CYS 226 1_555 ? ? ? ? ? ? ? 2.038 ? disulf3 disulf ? ? A CYS 184 SG ? ? ? 1_555 A CYS 197 SG ? ? A CYS 242 A CYS 255 1_555 ? ? ? ? ? ? ? 2.035 ? disulf4 disulf ? ? A CYS 246 SG ? ? ? 1_555 A CYS 322 SG ? ? A CYS 304 A CYS 393 1_555 ? ? ? ? ? ? ? 2.034 ? disulf5 disulf ? ? A CYS 266 SG ? ? ? 1_555 A CYS 313 SG ? ? A CYS 324 A CYS 384 1_555 ? ? ? ? ? ? ? 2.042 ? disulf6 disulf ? ? A CYS 364 SG ? ? ? 1_555 A CYS 388 SG ? ? A CYS 435 A CYS 459 1_555 ? ? ? ? ? ? ? 2.036 ? disulf7 disulf ? ? A CYS 376 SG ? ? ? 1_555 A CYS 400 SG ? ? A CYS 447 A CYS 471 1_555 ? ? ? ? ? ? ? 2.034 ? disulf8 disulf ? ? A CYS 381 SG ? ? ? 1_555 A CYS 408 SG ? ? A CYS 452 A CYS 479 1_555 ? ? ? ? ? ? ? 2.035 ? disulf9 disulf ? ? B CYS 59 SG ? ? ? 1_555 B CYS 228 SG ? ? C CYS 117 C CYS 286 1_555 ? ? ? ? ? ? ? 2.041 ? disulf10 disulf ? ? B CYS 136 SG ? ? ? 1_555 B CYS 168 SG ? ? C CYS 194 C CYS 226 1_555 ? ? ? ? ? ? ? 2.037 ? disulf11 disulf ? ? B CYS 184 SG ? ? ? 1_555 B CYS 197 SG ? ? C CYS 242 C CYS 255 1_555 ? ? ? ? ? ? ? 2.035 ? disulf12 disulf ? ? B CYS 246 SG ? ? ? 1_555 B CYS 322 SG ? ? C CYS 304 C CYS 393 1_555 ? ? ? ? ? ? ? 2.033 ? disulf13 disulf ? ? B CYS 266 SG ? ? ? 1_555 B CYS 313 SG ? ? C CYS 324 C CYS 384 1_555 ? ? ? ? ? ? ? 2.042 ? disulf14 disulf ? ? B CYS 364 SG ? ? ? 1_555 B CYS 388 SG ? ? C CYS 435 C CYS 459 1_555 ? ? ? ? ? ? ? 2.034 ? disulf15 disulf ? ? B CYS 376 SG ? ? ? 1_555 B CYS 400 SG ? ? C CYS 447 C CYS 471 1_555 ? ? ? ? ? ? ? 2.032 ? disulf16 disulf ? ? B CYS 381 SG ? ? ? 1_555 B CYS 408 SG ? ? C CYS 452 C CYS 479 1_555 ? ? ? ? ? ? ? 2.033 ? disulf17 disulf ? ? C CYS 59 SG ? ? ? 1_555 C CYS 228 SG ? ? E CYS 117 E CYS 286 1_555 ? ? ? ? ? ? ? 2.038 ? disulf18 disulf ? ? C CYS 136 SG ? ? ? 1_555 C CYS 168 SG ? ? E CYS 194 E CYS 226 1_555 ? ? ? ? ? ? ? 2.040 ? disulf19 disulf ? ? C CYS 184 SG ? ? ? 1_555 C CYS 197 SG ? ? E CYS 242 E CYS 255 1_555 ? ? ? ? ? ? ? 2.034 ? disulf20 disulf ? ? C CYS 246 SG ? ? ? 1_555 C CYS 322 SG ? ? E CYS 304 E CYS 393 1_555 ? ? ? ? ? ? ? 2.032 ? disulf21 disulf ? ? C CYS 266 SG ? ? ? 1_555 C CYS 313 SG ? ? E CYS 324 E CYS 384 1_555 ? ? ? ? ? ? ? 2.042 ? disulf22 disulf ? ? C CYS 364 SG ? ? ? 1_555 C CYS 388 SG ? ? E CYS 435 E CYS 459 1_555 ? ? ? ? ? ? ? 2.034 ? disulf23 disulf ? ? C CYS 376 SG ? ? ? 1_555 C CYS 400 SG ? ? E CYS 447 E CYS 471 1_555 ? ? ? ? ? ? ? 2.034 ? disulf24 disulf ? ? C CYS 381 SG ? ? ? 1_555 C CYS 408 SG ? ? E CYS 452 E CYS 479 1_555 ? ? ? ? ? ? ? 2.037 ? disulf25 disulf ? ? D CYS 21 SG B ? ? 1_555 D CYS 31 SG ? ? B CYS 1278 B CYS 1288 1_555 ? ? ? ? ? ? ? 2.032 ? disulf26 disulf ? ? E CYS 21 SG A ? ? 1_555 E CYS 31 SG ? ? D CYS 1278 D CYS 1288 1_555 ? ? ? ? ? ? ? 2.033 ? disulf27 disulf ? ? F CYS 21 SG B ? ? 1_555 F CYS 31 SG ? ? F CYS 1278 F CYS 1288 1_555 ? ? ? ? ? ? ? 2.034 ? covale1 covale one ? A ASN 28 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 86 A NAG 501 1_555 ? ? ? ? ? ? ? 1.443 ? covale2 covale one ? A THR 354 OG1 ? ? ? 1_555 H A2G . C1 ? ? A THR 425 A A2G 502 1_555 ? ? ? ? ? ? ? 1.489 ? covale3 covale one ? B ASN 28 ND2 ? ? ? 1_555 K NAG . C1 ? ? C ASN 86 C NAG 501 1_555 ? ? ? ? ? ? ? 1.442 ? covale4 covale one ? C ASN 28 ND2 ? ? ? 1_555 N NAG . C1 ? ? E ASN 86 E NAG 501 1_555 ? ? ? ? ? ? ? 1.440 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PRO 74 A . ? PRO 132 A PRO 75 A ? PRO 133 A 1 3.52 2 ASN 95 A . ? ASN 153 A PRO 96 A ? PRO 154 A 1 -3.88 3 SER 114 A . ? SER 172 A PRO 115 A ? PRO 173 A 1 -3.69 4 GLU 189 A . ? GLU 247 A PRO 190 A ? PRO 248 A 1 -2.24 5 PRO 74 B . ? PRO 132 C PRO 75 B ? PRO 133 C 1 3.17 6 ASN 95 B . ? ASN 153 C PRO 96 B ? PRO 154 C 1 -3.31 7 SER 114 B . ? SER 172 C PRO 115 B ? PRO 173 C 1 -2.10 8 GLU 189 B . ? GLU 247 C PRO 190 B ? PRO 248 C 1 -2.91 9 PRO 74 C . ? PRO 132 E PRO 75 C ? PRO 133 E 1 3.44 10 ASN 95 C . ? ASN 153 E PRO 96 C ? PRO 154 E 1 -4.04 11 SER 114 C . ? SER 172 E PRO 115 C ? PRO 173 E 1 -3.86 12 GLU 189 C . ? GLU 247 E PRO 190 C ? PRO 248 E 1 -1.71 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 2 ? AA2 ? 5 ? AA3 ? 2 ? AA4 ? 3 ? AA5 ? 6 ? AA6 ? 3 ? AA7 ? 2 ? AA8 ? 5 ? AA9 ? 2 ? AB1 ? 3 ? AB2 ? 6 ? AB3 ? 3 ? AB4 ? 2 ? AB5 ? 5 ? AB6 ? 2 ? AB7 ? 3 ? AB8 ? 6 ? AB9 ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA2 1 2 ? anti-parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA2 4 5 ? anti-parallel AA3 1 2 ? anti-parallel AA4 1 2 ? anti-parallel AA4 2 3 ? anti-parallel AA5 1 2 ? anti-parallel AA5 2 3 ? anti-parallel AA5 3 4 ? anti-parallel AA5 4 5 ? anti-parallel AA5 5 6 ? anti-parallel AA6 1 2 ? anti-parallel AA6 2 3 ? anti-parallel AA7 1 2 ? anti-parallel AA8 1 2 ? anti-parallel AA8 2 3 ? anti-parallel AA8 3 4 ? anti-parallel AA8 4 5 ? anti-parallel AA9 1 2 ? anti-parallel AB1 1 2 ? anti-parallel AB1 2 3 ? anti-parallel AB2 1 2 ? anti-parallel AB2 2 3 ? anti-parallel AB2 3 4 ? anti-parallel AB2 4 5 ? anti-parallel AB2 5 6 ? anti-parallel AB3 1 2 ? anti-parallel AB3 2 3 ? anti-parallel AB4 1 2 ? anti-parallel AB5 1 2 ? anti-parallel AB5 2 3 ? anti-parallel AB5 3 4 ? anti-parallel AB5 4 5 ? anti-parallel AB6 1 2 ? anti-parallel AB7 1 2 ? anti-parallel AB7 2 3 ? anti-parallel AB8 1 2 ? anti-parallel AB8 2 3 ? anti-parallel AB8 3 4 ? anti-parallel AB8 4 5 ? anti-parallel AB8 5 6 ? anti-parallel AB9 1 2 ? anti-parallel AB9 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 GLN A 43 ? VAL A 47 ? GLN A 101 VAL A 105 AA1 2 THR A 50 ? GLU A 54 ? THR A 108 GLU A 112 AA2 1 ILE A 61 ? TRP A 62 ? ILE A 119 TRP A 120 AA2 2 LEU A 210 ? GLY A 213 ? LEU A 268 GLY A 271 AA2 3 PHE A 159 ? ASP A 162 ? PHE A 217 ASP A 220 AA2 4 LEU A 167 ? ILE A 170 ? LEU A 225 ILE A 228 AA2 5 PHE A 116 ? PRO A 117 ? PHE A 174 PRO A 175 AA3 1 HIS A 65 ? LEU A 68 ? HIS A 123 LEU A 126 AA3 2 PHE A 198 ? ARG A 201 ? PHE A 256 ARG A 259 AA4 1 THR A 143 ? ALA A 145 ? THR A 201 ALA A 203 AA4 2 LEU D 22 ? ASN D 24 ? LEU B 1279 ASN B 1281 AA4 3 GLY D 28 ? VAL D 30 ? GLY B 1285 VAL B 1287 AA5 1 ARG A 245 ? ASP A 248 ? ARG A 303 ASP A 306 AA5 2 LEU A 233 ? LYS A 242 ? LEU A 291 LYS A 300 AA5 3 CYS A 322 ? THR A 333 ? CYS A 393 THR A 404 AA5 4 TYR A 300 ? VAL A 305 ? TYR A 371 VAL A 376 AA5 5 GLY A 311 ? SER A 316 ? GLY A 382 SER A 387 AA5 6 VAL A 256 ? ARG A 259 ? VAL A 314 ARG A 317 AA6 1 SER A 372 ? PHE A 373 ? SER A 443 PHE A 444 AA6 2 LYS A 382 ? VAL A 389 ? LYS A 453 VAL A 460 AA6 3 GLN A 392 ? ASP A 399 ? GLN A 463 ASP A 470 AA7 1 GLN B 43 ? VAL B 47 ? GLN C 101 VAL C 105 AA7 2 THR B 50 ? GLU B 54 ? THR C 108 GLU C 112 AA8 1 ILE B 61 ? TRP B 62 ? ILE C 119 TRP C 120 AA8 2 LEU B 210 ? GLY B 213 ? LEU C 268 GLY C 271 AA8 3 PHE B 159 ? ASP B 162 ? PHE C 217 ASP C 220 AA8 4 LEU B 167 ? ILE B 170 ? LEU C 225 ILE C 228 AA8 5 PHE B 116 ? PRO B 117 ? PHE C 174 PRO C 175 AA9 1 HIS B 65 ? LEU B 68 ? HIS C 123 LEU C 126 AA9 2 PHE B 198 ? ARG B 201 ? PHE C 256 ARG C 259 AB1 1 THR B 143 ? ALA B 145 ? THR C 201 ALA C 203 AB1 2 LEU E 22 ? ASN E 24 ? LEU D 1279 ASN D 1281 AB1 3 GLY E 28 ? VAL E 30 ? GLY D 1285 VAL D 1287 AB2 1 ARG B 245 ? ASP B 248 ? ARG C 303 ASP C 306 AB2 2 LEU B 233 ? LYS B 242 ? LEU C 291 LYS C 300 AB2 3 CYS B 322 ? THR B 333 ? CYS C 393 THR C 404 AB2 4 TYR B 300 ? VAL B 305 ? TYR C 371 VAL C 376 AB2 5 GLY B 311 ? SER B 316 ? GLY C 382 SER C 387 AB2 6 VAL B 256 ? ARG B 259 ? VAL C 314 ARG C 317 AB3 1 SER B 372 ? PHE B 373 ? SER C 443 PHE C 444 AB3 2 LYS B 382 ? VAL B 389 ? LYS C 453 VAL C 460 AB3 3 GLN B 392 ? ASP B 399 ? GLN C 463 ASP C 470 AB4 1 GLN C 43 ? VAL C 47 ? GLN E 101 VAL E 105 AB4 2 THR C 50 ? GLU C 54 ? THR E 108 GLU E 112 AB5 1 ILE C 61 ? TRP C 62 ? ILE E 119 TRP E 120 AB5 2 LEU C 210 ? GLY C 213 ? LEU E 268 GLY E 271 AB5 3 PHE C 159 ? ASP C 162 ? PHE E 217 ASP E 220 AB5 4 LEU C 167 ? ILE C 170 ? LEU E 225 ILE E 228 AB5 5 PHE C 116 ? PRO C 117 ? PHE E 174 PRO E 175 AB6 1 HIS C 65 ? LEU C 68 ? HIS E 123 LEU E 126 AB6 2 PHE C 198 ? ARG C 201 ? PHE E 256 ARG E 259 AB7 1 THR C 143 ? ALA C 145 ? THR E 201 ALA E 203 AB7 2 LEU F 22 ? ASN F 24 ? LEU F 1279 ASN F 1281 AB7 3 GLY F 28 ? VAL F 30 ? GLY F 1285 VAL F 1287 AB8 1 ARG C 245 ? ASP C 248 ? ARG E 303 ASP E 306 AB8 2 LEU C 233 ? LYS C 242 ? LEU E 291 LYS E 300 AB8 3 CYS C 322 ? THR C 333 ? CYS E 393 THR E 404 AB8 4 TYR C 300 ? VAL C 305 ? TYR E 371 VAL E 376 AB8 5 GLY C 311 ? SER C 316 ? GLY E 382 SER E 387 AB8 6 VAL C 256 ? ARG C 259 ? VAL E 314 ARG E 317 AB9 1 SER C 372 ? PHE C 373 ? SER E 443 PHE E 444 AB9 2 LYS C 382 ? VAL C 389 ? LYS E 453 VAL E 460 AB9 3 GLN C 392 ? ASP C 399 ? GLN E 463 ASP E 470 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N VAL A 47 ? N VAL A 105 O THR A 50 ? O THR A 108 AA2 1 2 N ILE A 61 ? N ILE A 119 O TYR A 212 ? O TYR A 270 AA2 2 3 O GLY A 213 ? O GLY A 271 N PHE A 159 ? N PHE A 217 AA2 3 4 N ASP A 162 ? N ASP A 220 O LEU A 167 ? O LEU A 225 AA2 4 5 O CYS A 168 ? O CYS A 226 N PHE A 116 ? N PHE A 174 AA3 1 2 N GLU A 67 ? N GLU A 125 O LYS A 199 ? O LYS A 257 AA4 1 2 N VAL A 144 ? N VAL A 202 O GLU D 23 ? O GLU B 1280 AA4 2 3 N LEU D 22 ? N LEU B 1279 O VAL D 30 ? O VAL B 1287 AA5 1 2 O LEU A 247 ? O LEU A 305 N VAL A 240 ? N VAL A 298 AA5 2 3 N ARG A 237 ? N ARG A 295 O VAL A 324 ? O VAL A 395 AA5 3 4 O VAL A 330 ? O VAL A 401 N TYR A 303 ? N TYR A 374 AA5 4 5 N TYR A 300 ? N TYR A 371 O SER A 316 ? O SER A 387 AA5 5 6 O LEU A 315 ? O LEU A 386 N VAL A 256 ? N VAL A 314 AA6 1 2 N SER A 372 ? N SER A 443 O THR A 386 ? O THR A 457 AA6 2 3 N SER A 387 ? N SER A 458 O GLN A 394 ? O GLN A 465 AA7 1 2 N VAL B 47 ? N VAL C 105 O THR B 50 ? O THR C 108 AA8 1 2 N ILE B 61 ? N ILE C 119 O TYR B 212 ? O TYR C 270 AA8 2 3 O GLY B 213 ? O GLY C 271 N PHE B 159 ? N PHE C 217 AA8 3 4 N ASP B 162 ? N ASP C 220 O LEU B 167 ? O LEU C 225 AA8 4 5 O CYS B 168 ? O CYS C 226 N PHE B 116 ? N PHE C 174 AA9 1 2 N GLU B 67 ? N GLU C 125 O LYS B 199 ? O LYS C 257 AB1 1 2 N VAL B 144 ? N VAL C 202 O GLU E 23 ? O GLU D 1280 AB1 2 3 N LEU E 22 ? N LEU D 1279 O VAL E 30 ? O VAL D 1287 AB2 1 2 O LEU B 247 ? O LEU C 305 N VAL B 240 ? N VAL C 298 AB2 2 3 N ARG B 237 ? N ARG C 295 O VAL B 324 ? O VAL C 395 AB2 3 4 O VAL B 330 ? O VAL C 401 N TYR B 303 ? N TYR C 374 AB2 4 5 N TYR B 300 ? N TYR C 371 O SER B 316 ? O SER C 387 AB2 5 6 O LEU B 315 ? O LEU C 386 N VAL B 256 ? N VAL C 314 AB3 1 2 N SER B 372 ? N SER C 443 O THR B 386 ? O THR C 457 AB3 2 3 N SER B 387 ? N SER C 458 O GLN B 394 ? O GLN C 465 AB4 1 2 N GLN C 43 ? N GLN E 101 O GLU C 54 ? O GLU E 112 AB5 1 2 N ILE C 61 ? N ILE E 119 O TYR C 212 ? O TYR E 270 AB5 2 3 O GLY C 213 ? O GLY E 271 N PHE C 159 ? N PHE E 217 AB5 3 4 N ASP C 162 ? N ASP E 220 O LEU C 167 ? O LEU E 225 AB5 4 5 O CYS C 168 ? O CYS E 226 N PHE C 116 ? N PHE E 174 AB6 1 2 N GLU C 67 ? N GLU E 125 O LYS C 199 ? O LYS E 257 AB7 1 2 N VAL C 144 ? N VAL E 202 O GLU F 23 ? O GLU F 1280 AB7 2 3 N LEU F 22 ? N LEU F 1279 O VAL F 30 ? O VAL F 1287 AB8 1 2 O LEU C 247 ? O LEU E 305 N VAL C 240 ? N VAL E 298 AB8 2 3 N ARG C 237 ? N ARG E 295 O VAL C 324 ? O VAL E 395 AB8 3 4 O VAL C 330 ? O VAL E 401 N TYR C 303 ? N TYR E 374 AB8 4 5 N TYR C 300 ? N TYR E 371 O SER C 316 ? O SER E 387 AB8 5 6 O LEU C 315 ? O LEU E 386 N VAL C 256 ? N VAL E 314 AB9 1 2 N SER C 372 ? N SER E 443 O THR C 386 ? O THR E 457 AB9 2 3 N LYS C 385 ? N LYS E 456 O THR C 396 ? O THR E 467 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A SO4 503 ? 1 'binding site for residue SO4 A 503' AC2 Software A SO4 504 ? 3 'binding site for residue SO4 A 504' AC3 Software C SO4 502 ? 3 'binding site for residue SO4 C 502' AC4 Software C SO4 503 ? 6 'binding site for residue SO4 C 503' AC5 Software E SO4 502 ? 3 'binding site for residue SO4 E 502' AC6 Software A NAG 501 ? 4 'binding site for Mono-Saccharide NAG A 501 bound to ASN A 86' AC7 Software A A2G 502 ? 6 'binding site for Mono-Saccharide A2G A 502 bound to THR A 425' AC8 Software C NAG 501 ? 4 'binding site for Mono-Saccharide NAG C 501 bound to ASN C 86' AC9 Software E NAG 501 ? 4 'binding site for Mono-Saccharide NAG E 501 bound to ASN E 86' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 1 LYS A 181 ? LYS A 239 . ? 1_555 ? 2 AC2 3 PRO A 343 ? PRO A 414 . ? 1_555 ? 3 AC2 3 ASN A 344 ? ASN A 415 . ? 1_555 ? 4 AC2 3 PHE A 345 ? PHE A 416 . ? 1_555 ? 5 AC3 3 GLY B 180 ? GLY C 238 . ? 1_555 ? 6 AC3 3 LYS B 181 ? LYS C 239 . ? 1_555 ? 7 AC3 3 HOH Q . ? HOH C 715 . ? 1_555 ? 8 AC4 6 LYS B 151 ? LYS C 209 . ? 6_555 ? 9 AC4 6 ALA B 152 ? ALA C 210 . ? 6_555 ? 10 AC4 6 ALA B 152 ? ALA C 210 . ? 1_555 ? 11 AC4 6 HOH Q . ? HOH C 601 . ? 1_555 ? 12 AC4 6 HOH Q . ? HOH C 601 . ? 6_555 ? 13 AC4 6 HOH Q . ? HOH C 603 . ? 1_555 ? 14 AC5 3 GLY C 180 ? GLY E 238 . ? 1_555 ? 15 AC5 3 LYS C 181 ? LYS E 239 . ? 1_555 ? 16 AC5 3 HOH R . ? HOH E 747 . ? 1_555 ? 17 AC6 4 GLU A 25 ? GLU A 83 . ? 1_555 ? 18 AC6 4 ASN A 28 ? ASN A 86 . ? 1_555 ? 19 AC6 4 HIS A 31 ? HIS A 89 . ? 1_555 ? 20 AC6 4 VAL A 319 ? VAL A 390 . ? 1_555 ? 21 AC7 6 ILE A 347 ? ILE A 418 . ? 1_555 ? 22 AC7 6 PRO A 351 ? PRO A 422 . ? 1_555 ? 23 AC7 6 THR A 354 ? THR A 425 . ? 1_555 ? 24 AC7 6 PRO A 355 ? PRO A 426 . ? 1_555 ? 25 AC7 6 PRO A 356 ? PRO A 427 . ? 1_555 ? 26 AC7 6 HOH P . ? HOH A 704 . ? 1_555 ? 27 AC8 4 GLU B 25 ? GLU C 83 . ? 1_555 ? 28 AC8 4 ASN B 28 ? ASN C 86 . ? 1_555 ? 29 AC8 4 HIS B 31 ? HIS C 89 . ? 1_555 ? 30 AC8 4 VAL B 319 ? VAL C 390 . ? 1_555 ? 31 AC9 4 GLU C 25 ? GLU E 83 . ? 1_555 ? 32 AC9 4 ASN C 28 ? ASN E 86 . ? 1_555 ? 33 AC9 4 HIS C 31 ? HIS E 89 . ? 1_555 ? 34 AC9 4 VAL C 319 ? VAL E 390 . ? 1_555 ? # _atom_sites.entry_id 4YIZ _atom_sites.fract_transf_matrix[1][1] 0.003760 _atom_sites.fract_transf_matrix[1][2] 0.002171 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.004342 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.010620 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . SER A 1 10 ? 26.481 -152.947 9.005 1.00 45.27 ? 68 SER A N 1 ATOM 2 C CA . SER A 1 10 ? 26.982 -151.885 9.869 1.00 51.57 ? 68 SER A CA 1 ATOM 3 C C . SER A 1 10 ? 26.111 -150.635 9.754 1.00 79.50 ? 68 SER A C 1 ATOM 4 O O . SER A 1 10 ? 25.073 -150.649 9.089 1.00 67.69 ? 68 SER A O 1 ATOM 5 C CB . SER A 1 10 ? 28.435 -151.554 9.522 1.00 74.29 ? 68 SER A CB 1 ATOM 6 O OG . SER A 1 10 ? 29.238 -152.722 9.538 1.00 74.96 ? 68 SER A OG 1 ATOM 7 N N . GLY A 1 11 ? 26.545 -149.557 10.402 1.00 70.30 ? 69 GLY A N 1 ATOM 8 C CA . GLY A 1 11 ? 25.760 -148.339 10.489 1.00 53.96 ? 69 GLY A CA 1 ATOM 9 C C . GLY A 1 11 ? 24.925 -148.337 11.757 1.00 31.73 ? 69 GLY A C 1 ATOM 10 O O . GLY A 1 11 ? 23.870 -147.706 11.822 1.00 38.46 ? 69 GLY A O 1 ATOM 11 N N . ASN A 1 12 ? 25.405 -149.058 12.766 1.00 31.53 ? 70 ASN A N 1 ATOM 12 C CA . ASN A 1 12 ? 24.739 -149.130 14.063 1.00 20.82 ? 70 ASN A CA 1 ATOM 13 C C . ASN A 1 12 ? 24.697 -147.752 14.718 1.00 22.25 ? 70 ASN A C 1 ATOM 14 O O . ASN A 1 12 ? 25.738 -147.228 15.114 1.00 29.01 ? 70 ASN A O 1 ATOM 15 C CB . ASN A 1 12 ? 25.462 -150.129 14.972 1.00 28.62 ? 70 ASN A CB 1 ATOM 16 C CG . ASN A 1 12 ? 24.742 -150.359 16.295 1.00 24.92 ? 70 ASN A CG 1 ATOM 17 O OD1 . ASN A 1 12 ? 23.767 -149.680 16.618 1.00 24.20 ? 70 ASN A OD1 1 ATOM 18 N ND2 . ASN A 1 12 ? 25.232 -151.318 17.070 1.00 25.58 ? 70 ASN A ND2 1 ATOM 19 N N . PRO A 1 13 ? 23.497 -147.158 14.842 1.00 20.78 ? 71 PRO A N 1 ATOM 20 C CA . PRO A 1 13 ? 23.441 -145.811 15.423 1.00 25.14 ? 71 PRO A CA 1 ATOM 21 C C . PRO A 1 13 ? 23.857 -145.771 16.890 1.00 34.30 ? 71 PRO A C 1 ATOM 22 O O . PRO A 1 13 ? 24.135 -144.690 17.412 1.00 30.82 ? 71 PRO A O 1 ATOM 23 C CB . PRO A 1 13 ? 21.969 -145.420 15.264 1.00 23.21 ? 71 PRO A CB 1 ATOM 24 C CG . PRO A 1 13 ? 21.236 -146.710 15.180 1.00 28.76 ? 71 PRO A CG 1 ATOM 25 C CD . PRO A 1 13 ? 22.158 -147.656 14.481 1.00 26.36 ? 71 PRO A CD 1 ATOM 26 N N . PHE A 1 14 ? 23.906 -146.930 17.541 1.00 20.42 ? 72 PHE A N 1 ATOM 27 C CA . PHE A 1 14 ? 24.289 -146.996 18.948 1.00 26.35 ? 72 PHE A CA 1 ATOM 28 C C . PHE A 1 14 ? 25.796 -147.224 19.107 1.00 29.22 ? 72 PHE A C 1 ATOM 29 O O . PHE A 1 14 ? 26.277 -147.512 20.201 1.00 31.76 ? 72 PHE A O 1 ATOM 30 C CB . PHE A 1 14 ? 23.489 -148.089 19.658 1.00 23.17 ? 72 PHE A CB 1 ATOM 31 C CG . PHE A 1 14 ? 22.004 -147.881 19.580 1.00 20.35 ? 72 PHE A CG 1 ATOM 32 C CD1 . PHE A 1 14 ? 21.360 -147.043 20.476 1.00 25.24 ? 72 PHE A CD1 1 ATOM 33 C CD2 . PHE A 1 14 ? 21.257 -148.499 18.593 1.00 17.11 ? 72 PHE A CD2 1 ATOM 34 C CE1 . PHE A 1 14 ? 19.996 -146.839 20.396 1.00 22.48 ? 72 PHE A CE1 1 ATOM 35 C CE2 . PHE A 1 14 ? 19.894 -148.299 18.508 1.00 19.54 ? 72 PHE A CE2 1 ATOM 36 C CZ . PHE A 1 14 ? 19.262 -147.467 19.410 1.00 20.85 ? 72 PHE A CZ 1 ATOM 37 N N . GLN A 1 15 ? 26.526 -147.087 18.002 1.00 22.02 ? 73 GLN A N 1 ATOM 38 C CA . GLN A 1 15 ? 27.988 -147.091 18.012 1.00 36.61 ? 73 GLN A CA 1 ATOM 39 C C . GLN A 1 15 ? 28.506 -145.961 17.123 1.00 36.50 ? 73 GLN A C 1 ATOM 40 O O . GLN A 1 15 ? 29.679 -145.935 16.753 1.00 39.78 ? 73 GLN A O 1 ATOM 41 C CB . GLN A 1 15 ? 28.538 -148.434 17.523 1.00 36.04 ? 73 GLN A CB 1 ATOM 42 C CG . GLN A 1 15 ? 28.034 -149.645 18.291 1.00 35.07 ? 73 GLN A CG 1 ATOM 43 C CD . GLN A 1 15 ? 28.604 -149.730 19.694 1.00 50.51 ? 73 GLN A CD 1 ATOM 44 O OE1 . GLN A 1 15 ? 29.820 -149.762 19.881 1.00 47.42 ? 73 GLN A OE1 1 ATOM 45 N NE2 . GLN A 1 15 ? 27.724 -149.768 20.690 1.00 37.09 ? 73 GLN A NE2 1 ATOM 46 N N . ALA A 1 16 ? 27.620 -145.026 16.793 1.00 37.19 ? 74 ALA A N 1 ATOM 47 C CA . ALA A 1 16 ? 27.909 -143.996 15.801 1.00 42.19 ? 74 ALA A CA 1 ATOM 48 C C . ALA A 1 16 ? 28.976 -143.001 16.259 1.00 41.70 ? 74 ALA A C 1 ATOM 49 O O . ALA A 1 16 ? 29.683 -142.429 15.431 1.00 50.43 ? 74 ALA A O 1 ATOM 50 C CB . ALA A 1 16 ? 26.628 -143.255 15.441 1.00 40.26 ? 74 ALA A CB 1 ATOM 51 N N . ASN A 1 17 ? 29.091 -142.792 17.567 1.00 45.64 ? 75 ASN A N 1 ATOM 52 C CA . ASN A 1 17 ? 30.059 -141.836 18.099 1.00 41.81 ? 75 ASN A CA 1 ATOM 53 C C . ASN A 1 17 ? 30.566 -142.223 19.489 1.00 46.36 ? 75 ASN A C 1 ATOM 54 O O . ASN A 1 17 ? 30.110 -143.202 20.078 1.00 40.05 ? 75 ASN A O 1 ATOM 55 C CB . ASN A 1 17 ? 29.444 -140.436 18.138 1.00 39.65 ? 75 ASN A CB 1 ATOM 56 C CG . ASN A 1 17 ? 28.169 -140.382 18.954 1.00 47.40 ? 75 ASN A CG 1 ATOM 57 O OD1 . ASN A 1 17 ? 28.202 -140.449 20.182 1.00 53.32 ? 75 ASN A OD1 1 ATOM 58 N ND2 . ASN A 1 17 ? 27.035 -140.252 18.274 1.00 46.38 ? 75 ASN A ND2 1 ATOM 59 N N . VAL A 1 18 ? 31.514 -141.444 20.002 1.00 41.74 ? 76 VAL A N 1 ATOM 60 C CA . VAL A 1 18 ? 32.176 -141.750 21.269 1.00 47.78 ? 76 VAL A CA 1 ATOM 61 C C . VAL A 1 18 ? 31.204 -141.743 22.449 1.00 41.54 ? 76 VAL A C 1 ATOM 62 O O . VAL A 1 18 ? 31.207 -142.664 23.265 1.00 45.58 ? 76 VAL A O 1 ATOM 63 C CB . VAL A 1 18 ? 33.320 -140.749 21.546 1.00 55.38 ? 76 VAL A CB 1 ATOM 64 C CG1 . VAL A 1 18 ? 33.907 -140.945 22.946 1.00 49.14 ? 76 VAL A CG1 1 ATOM 65 C CG2 . VAL A 1 18 ? 34.412 -140.895 20.492 1.00 54.33 ? 76 VAL A CG2 1 ATOM 66 N N . GLU A 1 19 ? 30.387 -140.697 22.538 1.00 42.74 ? 77 GLU A N 1 ATOM 67 C CA . GLU A 1 19 ? 29.405 -140.563 23.610 1.00 54.29 ? 77 GLU A CA 1 ATOM 68 C C . GLU A 1 19 ? 28.463 -141.760 23.639 1.00 48.27 ? 77 GLU A C 1 ATOM 69 O O . GLU A 1 19 ? 28.202 -142.345 24.694 1.00 40.00 ? 77 GLU A O 1 ATOM 70 C CB . GLU A 1 19 ? 28.600 -139.271 23.436 1.00 50.85 ? 77 GLU A CB 1 ATOM 71 C CG . GLU A 1 19 ? 29.444 -137.999 23.488 1.00 78.30 ? 77 GLU A CG 1 ATOM 72 C CD . GLU A 1 19 ? 28.862 -136.861 22.663 1.00 105.64 ? 77 GLU A CD 1 ATOM 73 O OE1 . GLU A 1 19 ? 28.570 -137.073 21.467 1.00 86.16 ? 77 GLU A OE1 1 ATOM 74 O OE2 . GLU A 1 19 ? 28.703 -135.750 23.212 1.00 96.55 ? 77 GLU A OE2 1 ATOM 75 N N . MET A 1 20 ? 27.962 -142.121 22.463 1.00 36.43 ? 78 MET A N 1 ATOM 76 C CA . MET A 1 20 ? 27.015 -143.218 22.323 1.00 35.45 ? 78 MET A CA 1 ATOM 77 C C . MET A 1 20 ? 27.647 -144.547 22.731 1.00 35.23 ? 78 MET A C 1 ATOM 78 O O . MET A 1 20 ? 27.045 -145.334 23.465 1.00 33.19 ? 78 MET A O 1 ATOM 79 C CB . MET A 1 20 ? 26.509 -143.290 20.883 1.00 37.83 ? 78 MET A CB 1 ATOM 80 C CG . MET A 1 20 ? 25.465 -144.356 20.650 1.00 46.31 ? 78 MET A CG 1 ATOM 81 S SD . MET A 1 20 ? 23.951 -144.071 21.583 1.00 41.65 ? 78 MET A SD 1 ATOM 82 C CE . MET A 1 20 ? 23.215 -142.734 20.642 1.00 36.17 ? 78 MET A CE 1 ATOM 83 N N . LYS A 1 21 ? 28.861 -144.793 22.245 1.00 31.98 ? 79 LYS A N 1 ATOM 84 C CA . LYS A 1 21 ? 29.614 -145.984 22.620 1.00 36.95 ? 79 LYS A CA 1 ATOM 85 C C . LYS A 1 21 ? 29.809 -146.032 24.128 1.00 43.19 ? 79 LYS A C 1 ATOM 86 O O . LYS A 1 21 ? 29.582 -147.064 24.764 1.00 38.66 ? 79 LYS A O 1 ATOM 87 C CB . LYS A 1 21 ? 30.973 -146.012 21.920 1.00 34.24 ? 79 LYS A CB 1 ATOM 88 C CG . LYS A 1 21 ? 30.917 -146.418 20.460 1.00 45.95 ? 79 LYS A CG 1 ATOM 89 C CD . LYS A 1 21 ? 32.308 -146.468 19.844 1.00 48.10 ? 79 LYS A CD 1 ATOM 90 C CE . LYS A 1 21 ? 32.348 -147.383 18.630 1.00 58.86 ? 79 LYS A CE 1 ATOM 91 N NZ . LYS A 1 21 ? 33.639 -147.283 17.891 1.00 84.93 ? 79 LYS A NZ 1 ATOM 92 N N . THR A 1 22 ? 30.238 -144.904 24.687 1.00 34.93 ? 80 THR A N 1 ATOM 93 C CA . THR A 1 22 ? 30.423 -144.772 26.125 1.00 37.44 ? 80 THR A CA 1 ATOM 94 C C . THR A 1 22 ? 29.135 -145.121 26.852 1.00 38.84 ? 80 THR A C 1 ATOM 95 O O . THR A 1 22 ? 29.155 -145.852 27.843 1.00 28.43 ? 80 THR A O 1 ATOM 96 C CB . THR A 1 22 ? 30.865 -143.343 26.510 1.00 42.79 ? 80 THR A CB 1 ATOM 97 O OG1 . THR A 1 22 ? 32.159 -143.074 25.956 1.00 43.04 ? 80 THR A OG1 1 ATOM 98 C CG2 . THR A 1 22 ? 30.928 -143.176 28.029 1.00 41.01 ? 80 THR A CG2 1 ATOM 99 N N . PHE A 1 23 ? 28.014 -144.600 26.363 1.00 33.51 ? 81 PHE A N 1 ATOM 100 C CA . PHE A 1 23 ? 26.726 -144.930 26.956 1.00 32.97 ? 81 PHE A CA 1 ATOM 101 C C . PHE A 1 23 ? 26.411 -146.419 26.843 1.00 36.40 ? 81 PHE A C 1 ATOM 102 O O . PHE A 1 23 ? 25.969 -147.032 27.805 1.00 23.72 ? 81 PHE A O 1 ATOM 103 C CB . PHE A 1 23 ? 25.598 -144.122 26.313 1.00 29.39 ? 81 PHE A CB 1 ATOM 104 C CG . PHE A 1 23 ? 24.229 -144.551 26.759 1.00 29.22 ? 81 PHE A CG 1 ATOM 105 C CD1 . PHE A 1 23 ? 23.740 -144.171 27.996 1.00 35.88 ? 81 PHE A CD1 1 ATOM 106 C CD2 . PHE A 1 23 ? 23.438 -145.347 25.947 1.00 36.33 ? 81 PHE A CD2 1 ATOM 107 C CE1 . PHE A 1 23 ? 22.484 -144.571 28.415 1.00 39.55 ? 81 PHE A CE1 1 ATOM 108 C CE2 . PHE A 1 23 ? 22.181 -145.749 26.359 1.00 30.47 ? 81 PHE A CE2 1 ATOM 109 C CZ . PHE A 1 23 ? 21.705 -145.362 27.595 1.00 31.24 ? 81 PHE A CZ 1 ATOM 110 N N . MET A 1 24 ? 26.629 -147.007 25.672 1.00 28.98 ? 82 MET A N 1 ATOM 111 C CA . MET A 1 24 ? 26.292 -148.417 25.485 1.00 26.52 ? 82 MET A CA 1 ATOM 112 C C . MET A 1 24 ? 27.249 -149.358 26.211 1.00 34.05 ? 82 MET A C 1 ATOM 113 O O . MET A 1 24 ? 26.884 -150.487 26.541 1.00 30.53 ? 82 MET A O 1 ATOM 114 C CB . MET A 1 24 ? 26.268 -148.768 23.996 1.00 29.00 ? 82 MET A CB 1 ATOM 115 C CG . MET A 1 24 ? 25.046 -148.241 23.262 1.00 32.84 ? 82 MET A CG 1 ATOM 116 S SD . MET A 1 24 ? 23.485 -148.826 23.959 1.00 32.88 ? 82 MET A SD 1 ATOM 117 C CE . MET A 1 24 ? 23.594 -150.580 23.622 1.00 26.94 ? 82 MET A CE 1 ATOM 118 N N . GLU A 1 25 ? 28.471 -148.903 26.461 1.00 22.33 ? 83 GLU A N 1 ATOM 119 C CA . GLU A 1 25 ? 29.461 -149.752 27.117 1.00 32.49 ? 83 GLU A CA 1 ATOM 120 C C . GLU A 1 25 ? 29.163 -150.046 28.589 1.00 31.62 ? 83 GLU A C 1 ATOM 121 O O . GLU A 1 25 ? 29.683 -151.017 29.134 1.00 27.69 ? 83 GLU A O 1 ATOM 122 C CB . GLU A 1 25 ? 30.854 -149.129 27.007 1.00 45.23 ? 83 GLU A CB 1 ATOM 123 C CG . GLU A 1 25 ? 31.808 -149.938 26.138 1.00 81.08 ? 83 GLU A CG 1 ATOM 124 C CD . GLU A 1 25 ? 32.136 -151.297 26.732 1.00 75.18 ? 83 GLU A CD 1 ATOM 125 O OE1 . GLU A 1 25 ? 32.385 -151.368 27.955 1.00 59.37 ? 83 GLU A OE1 1 ATOM 126 O OE2 . GLU A 1 25 ? 32.139 -152.295 25.979 1.00 52.33 ? 83 GLU A OE2 1 ATOM 127 N N . ARG A 1 26 ? 28.325 -149.234 29.207 1.00 26.68 ? 84 ARG A N 1 ATOM 128 C CA . ARG A 1 26 ? 27.964 -149.409 30.593 1.00 31.15 ? 84 ARG A CA 1 ATOM 129 C C . ARG A 1 26 ? 27.188 -150.709 30.810 1.00 28.44 ? 84 ARG A C 1 ATOM 130 O O . ARG A 1 26 ? 27.040 -151.150 31.922 1.00 24.23 ? 84 ARG A O 1 ATOM 131 C CB . ARG A 1 26 ? 27.175 -148.205 31.137 1.00 33.33 ? 84 ARG A CB 1 ATOM 132 C CG . ARG A 1 26 ? 25.734 -148.128 30.681 1.00 49.98 ? 84 ARG A CG 1 ATOM 133 C CD . ARG A 1 26 ? 24.905 -147.088 31.426 1.00 53.38 ? 84 ARG A CD 1 ATOM 134 N NE . ARG A 1 26 ? 25.435 -145.742 31.295 1.00 59.28 ? 84 ARG A NE 1 ATOM 135 C CZ . ARG A 1 26 ? 24.778 -144.648 31.656 1.00 75.90 ? 84 ARG A CZ 1 ATOM 136 N NH1 . ARG A 1 26 ? 25.328 -143.452 31.506 1.00 56.61 ? 84 ARG A NH1 1 ATOM 137 N NH2 . ARG A 1 26 ? 23.556 -144.749 32.156 1.00 75.57 ? 84 ARG A NH2 1 ATOM 138 N N . PHE A 1 27 ? 26.687 -151.298 29.735 1.00 22.49 ? 85 PHE A N 1 ATOM 139 C CA . PHE A 1 27 ? 25.891 -152.518 29.809 1.00 25.24 ? 85 PHE A CA 1 ATOM 140 C C . PHE A 1 27 ? 26.741 -153.774 29.655 1.00 20.44 ? 85 PHE A C 1 ATOM 141 O O . PHE A 1 27 ? 26.235 -154.881 29.799 1.00 32.03 ? 85 PHE A O 1 ATOM 142 C CB . PHE A 1 27 ? 24.795 -152.503 28.748 1.00 20.29 ? 85 PHE A CB 1 ATOM 143 C CG . PHE A 1 27 ? 23.780 -151.422 28.951 1.00 20.26 ? 85 PHE A CG 1 ATOM 144 C CD1 . PHE A 1 27 ? 22.932 -151.448 30.046 1.00 19.56 ? 85 PHE A CD1 1 ATOM 145 C CD2 . PHE A 1 27 ? 23.669 -150.383 28.045 1.00 26.52 ? 85 PHE A CD2 1 ATOM 146 C CE1 . PHE A 1 27 ? 21.994 -150.450 30.236 1.00 25.91 ? 85 PHE A CE1 1 ATOM 147 C CE2 . PHE A 1 27 ? 22.733 -149.386 28.227 1.00 29.57 ? 85 PHE A CE2 1 ATOM 148 C CZ . PHE A 1 27 ? 21.894 -149.418 29.323 1.00 21.78 ? 85 PHE A CZ 1 ATOM 149 N N . ASN A 1 28 ? 28.026 -153.610 29.364 1.00 19.96 ? 86 ASN A N 1 ATOM 150 C CA . ASN A 1 28 ? 28.919 -154.758 29.254 1.00 21.50 ? 86 ASN A CA 1 ATOM 151 C C . ASN A 1 28 ? 29.503 -155.113 30.618 1.00 22.14 ? 86 ASN A C 1 ATOM 152 O O . ASN A 1 28 ? 30.511 -154.550 31.040 1.00 16.86 ? 86 ASN A O 1 ATOM 153 C CB . ASN A 1 28 ? 30.039 -154.482 28.250 1.00 24.10 ? 86 ASN A CB 1 ATOM 154 C CG . ASN A 1 28 ? 30.835 -155.729 27.907 1.00 23.03 ? 86 ASN A CG 1 ATOM 155 O OD1 . ASN A 1 28 ? 30.838 -156.704 28.660 1.00 23.17 ? 86 ASN A OD1 1 ATOM 156 N ND2 . ASN A 1 28 ? 31.513 -155.705 26.763 1.00 24.01 ? 86 ASN A ND2 1 ATOM 157 N N . LEU A 1 29 ? 28.866 -156.058 31.299 1.00 19.60 ? 87 LEU A N 1 ATOM 158 C CA . LEU A 1 29 ? 29.284 -156.443 32.639 1.00 23.41 ? 87 LEU A CA 1 ATOM 159 C C . LEU A 1 29 ? 30.557 -157.284 32.613 1.00 24.73 ? 87 LEU A C 1 ATOM 160 O O . LEU A 1 29 ? 31.264 -157.380 33.612 1.00 21.04 ? 87 LEU A O 1 ATOM 161 C CB . LEU A 1 29 ? 28.159 -157.198 33.342 1.00 17.79 ? 87 LEU A CB 1 ATOM 162 C CG . LEU A 1 29 ? 26.963 -156.317 33.711 1.00 21.46 ? 87 LEU A CG 1 ATOM 163 C CD1 . LEU A 1 29 ? 25.761 -157.170 34.092 1.00 18.65 ? 87 LEU A CD1 1 ATOM 164 C CD2 . LEU A 1 29 ? 27.329 -155.369 34.845 1.00 20.66 ? 87 LEU A CD2 1 ATOM 165 N N . THR A 1 30 ? 30.855 -157.887 31.469 1.00 23.41 ? 88 THR A N 1 ATOM 166 C CA . THR A 1 30 ? 32.092 -158.642 31.325 1.00 26.08 ? 88 THR A CA 1 ATOM 167 C C . THR A 1 30 ? 33.284 -157.690 31.366 1.00 31.24 ? 88 THR A C 1 ATOM 168 O O . THR A 1 30 ? 34.334 -158.018 31.916 1.00 30.24 ? 88 THR A O 1 ATOM 169 C CB . THR A 1 30 ? 32.121 -159.449 30.011 1.00 22.14 ? 88 THR A CB 1 ATOM 170 O OG1 . THR A 1 30 ? 30.966 -160.294 29.939 1.00 30.88 ? 88 THR A OG1 1 ATOM 171 C CG2 . THR A 1 30 ? 33.374 -160.309 29.931 1.00 24.91 ? 88 THR A CG2 1 ATOM 172 N N . HIS A 1 31 ? 33.107 -156.504 30.793 1.00 25.45 ? 89 HIS A N 1 ATOM 173 C CA . HIS A 1 31 ? 34.186 -155.529 30.693 1.00 30.13 ? 89 HIS A CA 1 ATOM 174 C C . HIS A 1 31 ? 34.402 -154.769 31.996 1.00 31.00 ? 89 HIS A C 1 ATOM 175 O O . HIS A 1 31 ? 35.534 -154.612 32.450 1.00 25.87 ? 89 HIS A O 1 ATOM 176 C CB . HIS A 1 31 ? 33.898 -154.531 29.571 1.00 29.26 ? 89 HIS A CB 1 ATOM 177 C CG . HIS A 1 31 ? 35.018 -153.571 29.315 1.00 39.39 ? 89 HIS A CG 1 ATOM 178 N ND1 . HIS A 1 31 ? 34.808 -152.232 29.061 1.00 49.05 ? 89 HIS A ND1 1 ATOM 179 C CD2 . HIS A 1 31 ? 36.359 -153.756 29.268 1.00 45.50 ? 89 HIS A CD2 1 ATOM 180 C CE1 . HIS A 1 31 ? 35.971 -151.634 28.873 1.00 48.68 ? 89 HIS A CE1 1 ATOM 181 N NE2 . HIS A 1 31 ? 36.928 -152.536 28.993 1.00 52.33 ? 89 HIS A NE2 1 ATOM 182 N N . HIS A 1 32 ? 33.311 -154.297 32.591 1.00 27.01 ? 90 HIS A N 1 ATOM 183 C CA . HIS A 1 32 ? 33.396 -153.380 33.722 1.00 37.95 ? 90 HIS A CA 1 ATOM 184 C C . HIS A 1 32 ? 33.298 -154.074 35.082 1.00 28.85 ? 90 HIS A C 1 ATOM 185 O O . HIS A 1 32 ? 34.052 -153.747 35.995 1.00 38.44 ? 90 HIS A O 1 ATOM 186 C CB . HIS A 1 32 ? 32.308 -152.314 33.594 1.00 40.51 ? 90 HIS A CB 1 ATOM 187 C CG . HIS A 1 32 ? 32.543 -151.353 32.469 1.00 46.31 ? 90 HIS A CG 1 ATOM 188 N ND1 . HIS A 1 32 ? 31.517 -150.747 31.778 1.00 43.48 ? 90 HIS A ND1 1 ATOM 189 C CD2 . HIS A 1 32 ? 33.691 -150.893 31.915 1.00 49.60 ? 90 HIS A CD2 1 ATOM 190 C CE1 . HIS A 1 32 ? 32.021 -149.955 30.848 1.00 37.11 ? 90 HIS A CE1 1 ATOM 191 N NE2 . HIS A 1 32 ? 33.339 -150.026 30.910 1.00 52.10 ? 90 HIS A NE2 1 ATOM 192 N N . HIS A 1 33 ? 32.384 -155.030 35.218 1.00 24.27 ? 91 HIS A N 1 ATOM 193 C CA . HIS A 1 33 ? 32.210 -155.737 36.488 1.00 24.39 ? 91 HIS A CA 1 ATOM 194 C C . HIS A 1 33 ? 33.269 -156.831 36.650 1.00 26.06 ? 91 HIS A C 1 ATOM 195 O O . HIS A 1 33 ? 33.931 -156.908 37.682 1.00 19.92 ? 91 HIS A O 1 ATOM 196 C CB . HIS A 1 33 ? 30.803 -156.326 36.580 1.00 19.64 ? 91 HIS A CB 1 ATOM 197 C CG . HIS A 1 33 ? 30.530 -157.043 37.863 1.00 24.54 ? 91 HIS A CG 1 ATOM 198 N ND1 . HIS A 1 33 ? 30.407 -156.393 39.071 1.00 20.24 ? 91 HIS A ND1 1 ATOM 199 C CD2 . HIS A 1 33 ? 30.347 -158.358 38.121 1.00 17.43 ? 91 HIS A CD2 1 ATOM 200 C CE1 . HIS A 1 33 ? 30.160 -157.279 40.020 1.00 22.92 ? 91 HIS A CE1 1 ATOM 201 N NE2 . HIS A 1 33 ? 30.121 -158.479 39.470 1.00 22.03 ? 91 HIS A NE2 1 ATOM 202 N N . GLN A 1 34 ? 33.408 -157.673 35.628 1.00 18.65 ? 92 GLN A N 1 ATOM 203 C CA . GLN A 1 34 ? 34.524 -158.619 35.516 1.00 22.66 ? 92 GLN A CA 1 ATOM 204 C C . GLN A 1 34 ? 34.532 -159.744 36.548 1.00 23.61 ? 92 GLN A C 1 ATOM 205 O O . GLN A 1 34 ? 35.574 -160.349 36.791 1.00 17.60 ? 92 GLN A O 1 ATOM 206 C CB . GLN A 1 34 ? 35.860 -157.875 35.611 1.00 28.00 ? 92 GLN A CB 1 ATOM 207 C CG . GLN A 1 34 ? 36.007 -156.723 34.643 1.00 43.60 ? 92 GLN A CG 1 ATOM 208 C CD . GLN A 1 34 ? 37.421 -156.185 34.603 1.00 48.53 ? 92 GLN A CD 1 ATOM 209 O OE1 . GLN A 1 34 ? 37.722 -155.149 35.194 1.00 44.23 ? 92 GLN A OE1 1 ATOM 210 N NE2 . GLN A 1 34 ? 38.302 -156.892 33.904 1.00 62.78 ? 92 GLN A NE2 1 ATOM 211 N N . SER A 1 35 ? 33.387 -160.039 37.149 1.00 22.98 ? 93 SER A N 1 ATOM 212 C CA . SER A 1 35 ? 33.322 -161.125 38.119 1.00 27.08 ? 93 SER A CA 1 ATOM 213 C C . SER A 1 35 ? 31.915 -161.690 38.197 1.00 16.68 ? 93 SER A C 1 ATOM 214 O O . SER A 1 35 ? 31.019 -161.236 37.493 1.00 21.22 ? 93 SER A O 1 ATOM 215 C CB . SER A 1 35 ? 33.775 -160.638 39.497 1.00 26.61 ? 93 SER A CB 1 ATOM 216 O OG . SER A 1 35 ? 34.049 -161.731 40.356 1.00 29.74 ? 93 SER A OG 1 ATOM 217 N N . GLY A 1 36 ? 31.725 -162.686 39.052 1.00 18.32 ? 94 GLY A N 1 ATOM 218 C CA . GLY A 1 36 ? 30.405 -163.240 39.272 1.00 17.45 ? 94 GLY A CA 1 ATOM 219 C C . GLY A 1 36 ? 29.470 -162.174 39.808 1.00 19.84 ? 94 GLY A C 1 ATOM 220 O O . GLY A 1 36 ? 29.915 -161.190 40.400 1.00 16.32 ? 94 GLY A O 1 ATOM 221 N N . ILE A 1 37 ? 28.174 -162.365 39.586 1.00 19.09 ? 95 ILE A N 1 ATOM 222 C CA . ILE A 1 37 ? 27.163 -161.410 40.024 1.00 20.47 ? 95 ILE A CA 1 ATOM 223 C C . ILE A 1 37 ? 26.254 -162.059 41.060 1.00 18.26 ? 95 ILE A C 1 ATOM 224 O O . ILE A 1 37 ? 26.074 -161.530 42.157 1.00 16.75 ? 95 ILE A O 1 ATOM 225 C CB . ILE A 1 37 ? 26.341 -160.893 38.828 1.00 14.25 ? 95 ILE A CB 1 ATOM 226 C CG1 . ILE A 1 37 ? 27.244 -160.071 37.905 1.00 21.64 ? 95 ILE A CG1 1 ATOM 227 C CG2 . ILE A 1 37 ? 25.164 -160.039 39.295 1.00 19.95 ? 95 ILE A CG2 1 ATOM 228 C CD1 . ILE A 1 37 ? 26.627 -159.737 36.568 1.00 19.05 ? 95 ILE A CD1 1 ATOM 229 N N . TYR A 1 38 ? 25.686 -163.207 40.710 1.00 13.11 ? 96 TYR A N 1 ATOM 230 C CA . TYR A 1 38 ? 24.871 -163.970 41.645 1.00 18.50 ? 96 TYR A CA 1 ATOM 231 C C . TYR A 1 38 ? 25.727 -164.354 42.848 1.00 15.42 ? 96 TYR A C 1 ATOM 232 O O . TYR A 1 38 ? 25.398 -164.026 43.989 1.00 16.74 ? 96 TYR A O 1 ATOM 233 C CB . TYR A 1 38 ? 24.292 -165.208 40.959 1.00 12.23 ? 96 TYR A CB 1 ATOM 234 C CG . TYR A 1 38 ? 23.295 -165.969 41.796 1.00 13.77 ? 96 TYR A CG 1 ATOM 235 C CD1 . TYR A 1 38 ? 22.075 -165.404 42.139 1.00 17.13 ? 96 TYR A CD1 1 ATOM 236 C CD2 . TYR A 1 38 ? 23.566 -167.259 42.229 1.00 17.28 ? 96 TYR A CD2 1 ATOM 237 C CE1 . TYR A 1 38 ? 21.158 -166.097 42.900 1.00 21.63 ? 96 TYR A CE1 1 ATOM 238 C CE2 . TYR A 1 38 ? 22.653 -167.962 42.990 1.00 16.29 ? 96 TYR A CE2 1 ATOM 239 C CZ . TYR A 1 38 ? 21.451 -167.376 43.322 1.00 20.31 ? 96 TYR A CZ 1 ATOM 240 O OH . TYR A 1 38 ? 20.535 -168.068 44.081 1.00 27.49 ? 96 TYR A OH 1 ATOM 241 N N . VAL A 1 39 ? 26.832 -165.041 42.573 1.00 15.81 ? 97 VAL A N 1 ATOM 242 C CA . VAL A 1 39 ? 27.883 -165.263 43.557 1.00 17.72 ? 97 VAL A CA 1 ATOM 243 C C . VAL A 1 39 ? 29.187 -164.677 43.022 1.00 22.26 ? 97 VAL A C 1 ATOM 244 O O . VAL A 1 39 ? 29.644 -165.050 41.942 1.00 20.19 ? 97 VAL A O 1 ATOM 245 C CB . VAL A 1 39 ? 28.073 -166.758 43.872 1.00 20.50 ? 97 VAL A CB 1 ATOM 246 C CG1 . VAL A 1 39 ? 29.293 -166.973 44.755 1.00 21.98 ? 97 VAL A CG1 1 ATOM 247 C CG2 . VAL A 1 39 ? 26.829 -167.316 44.543 1.00 16.42 ? 97 VAL A CG2 1 ATOM 248 N N . ASP A 1 40 ? 29.779 -163.763 43.786 1.00 20.04 ? 98 ASP A N 1 ATOM 249 C CA . ASP A 1 40 ? 31.024 -163.109 43.396 1.00 16.57 ? 98 ASP A CA 1 ATOM 250 C C . ASP A 1 40 ? 32.184 -163.605 44.254 1.00 21.51 ? 98 ASP A C 1 ATOM 251 O O . ASP A 1 40 ? 32.280 -163.280 45.437 1.00 20.91 ? 98 ASP A O 1 ATOM 252 C CB . ASP A 1 40 ? 30.885 -161.587 43.509 1.00 18.62 ? 98 ASP A CB 1 ATOM 253 C CG . ASP A 1 40 ? 32.165 -160.845 43.148 1.00 26.12 ? 98 ASP A CG 1 ATOM 254 O OD1 . ASP A 1 40 ? 33.134 -161.485 42.683 1.00 23.36 ? 98 ASP A OD1 1 ATOM 255 O OD2 . ASP A 1 40 ? 32.197 -159.608 43.316 1.00 24.00 ? 98 ASP A OD2 1 ATOM 256 N N . LEU A 1 41 ? 33.060 -164.392 43.637 1.00 23.44 ? 99 LEU A N 1 ATOM 257 C CA . LEU A 1 41 ? 34.272 -164.889 44.280 1.00 22.55 ? 99 LEU A CA 1 ATOM 258 C C . LEU A 1 41 ? 35.398 -164.895 43.256 1.00 27.06 ? 99 LEU A C 1 ATOM 259 O O . LEU A 1 41 ? 36.051 -165.914 43.035 1.00 28.11 ? 99 LEU A O 1 ATOM 260 C CB . LEU A 1 41 ? 34.056 -166.292 44.848 1.00 22.25 ? 99 LEU A CB 1 ATOM 261 C CG . LEU A 1 41 ? 33.013 -166.407 45.956 1.00 20.47 ? 99 LEU A CG 1 ATOM 262 C CD1 . LEU A 1 41 ? 32.634 -167.860 46.182 1.00 23.60 ? 99 LEU A CD1 1 ATOM 263 C CD2 . LEU A 1 41 ? 33.536 -165.787 47.239 1.00 21.13 ? 99 LEU A CD2 1 ATOM 264 N N . GLY A 1 42 ? 35.617 -163.742 42.634 1.00 25.66 ? 100 GLY A N 1 ATOM 265 C CA . GLY A 1 42 ? 36.476 -163.649 41.470 1.00 32.97 ? 100 GLY A CA 1 ATOM 266 C C . GLY A 1 42 ? 37.968 -163.671 41.735 1.00 34.16 ? 100 GLY A C 1 ATOM 267 O O . GLY A 1 42 ? 38.744 -163.941 40.817 1.00 34.93 ? 100 GLY A O 1 ATOM 268 N N . GLN A 1 43 ? 38.379 -163.383 42.967 1.00 28.12 ? 101 GLN A N 1 ATOM 269 C CA . GLN A 1 43 ? 39.803 -163.302 43.276 1.00 29.86 ? 101 GLN A CA 1 ATOM 270 C C . GLN A 1 43 ? 40.240 -164.308 44.334 1.00 28.89 ? 101 GLN A C 1 ATOM 271 O O . GLN A 1 43 ? 39.415 -164.896 45.035 1.00 31.24 ? 101 GLN A O 1 ATOM 272 C CB . GLN A 1 43 ? 40.158 -161.880 43.719 1.00 29.15 ? 101 GLN A CB 1 ATOM 273 C CG . GLN A 1 43 ? 40.410 -160.931 42.549 1.00 27.41 ? 101 GLN A CG 1 ATOM 274 C CD . GLN A 1 43 ? 40.549 -159.469 42.956 1.00 45.26 ? 101 GLN A CD 1 ATOM 275 O OE1 . GLN A 1 43 ? 40.680 -158.596 42.098 1.00 39.74 ? 101 GLN A OE1 1 ATOM 276 N NE2 . GLN A 1 43 ? 40.524 -159.195 44.260 1.00 41.82 ? 101 GLN A NE2 1 ATOM 277 N N . ASP A 1 44 ? 41.551 -164.511 44.411 1.00 33.72 ? 102 ASP A N 1 ATOM 278 C CA . ASP A 1 44 ? 42.161 -165.384 45.404 1.00 30.81 ? 102 ASP A CA 1 ATOM 279 C C . ASP A 1 44 ? 43.254 -164.615 46.136 1.00 38.68 ? 102 ASP A C 1 ATOM 280 O O . ASP A 1 44 ? 44.083 -163.958 45.506 1.00 38.79 ? 102 ASP A O 1 ATOM 281 C CB . ASP A 1 44 ? 42.742 -166.639 44.748 1.00 37.03 ? 102 ASP A CB 1 ATOM 282 C CG . ASP A 1 44 ? 41.705 -167.427 43.969 1.00 60.95 ? 102 ASP A CG 1 ATOM 283 O OD1 . ASP A 1 44 ? 40.917 -168.163 44.601 1.00 57.27 ? 102 ASP A OD1 1 ATOM 284 O OD2 . ASP A 1 44 ? 41.682 -167.317 42.725 1.00 55.75 ? 102 ASP A OD2 1 ATOM 285 N N . LYS A 1 45 ? 43.248 -164.695 47.463 1.00 35.07 ? 103 LYS A N 1 ATOM 286 C CA . LYS A 1 45 ? 44.227 -163.976 48.273 1.00 31.56 ? 103 LYS A CA 1 ATOM 287 C C . LYS A 1 45 ? 44.839 -164.872 49.339 1.00 34.13 ? 103 LYS A C 1 ATOM 288 O O . LYS A 1 45 ? 44.168 -165.740 49.900 1.00 34.66 ? 103 LYS A O 1 ATOM 289 C CB . LYS A 1 45 ? 43.581 -162.751 48.927 1.00 31.58 ? 103 LYS A CB 1 ATOM 290 C CG . LYS A 1 45 ? 43.186 -161.658 47.945 1.00 27.35 ? 103 LYS A CG 1 ATOM 291 C CD . LYS A 1 45 ? 44.406 -160.989 47.324 1.00 30.86 ? 103 LYS A CD 1 ATOM 292 C CE . LYS A 1 45 ? 44.015 -160.040 46.209 1.00 29.91 ? 103 LYS A CE 1 ATOM 293 N NZ . LYS A 1 45 ? 43.041 -159.014 46.665 1.00 26.60 ? 103 LYS A NZ 1 ATOM 294 N N . GLU A 1 46 ? 46.120 -164.649 49.610 1.00 36.10 ? 104 GLU A N 1 ATOM 295 C CA . GLU A 1 46 ? 46.848 -165.447 50.583 1.00 41.18 ? 104 GLU A CA 1 ATOM 296 C C . GLU A 1 46 ? 46.862 -164.769 51.947 1.00 40.53 ? 104 GLU A C 1 ATOM 297 O O . GLU A 1 46 ? 47.247 -163.606 52.076 1.00 36.05 ? 104 GLU A O 1 ATOM 298 C CB . GLU A 1 46 ? 48.279 -165.700 50.107 1.00 46.54 ? 104 GLU A CB 1 ATOM 299 C CG . GLU A 1 46 ? 48.976 -166.844 50.836 1.00 69.62 ? 104 GLU A CG 1 ATOM 300 C CD . GLU A 1 46 ? 50.220 -167.333 50.114 1.00 84.19 ? 104 GLU A CD 1 ATOM 301 O OE1 . GLU A 1 46 ? 50.175 -167.478 48.873 1.00 81.30 ? 104 GLU A OE1 1 ATOM 302 O OE2 . GLU A 1 46 ? 51.243 -167.573 50.788 1.00 75.96 ? 104 GLU A OE2 1 ATOM 303 N N . VAL A 1 47 ? 46.419 -165.511 52.956 1.00 39.46 ? 105 VAL A N 1 ATOM 304 C CA . VAL A 1 47 ? 46.494 -165.075 54.342 1.00 45.25 ? 105 VAL A CA 1 ATOM 305 C C . VAL A 1 47 ? 47.114 -166.201 55.161 1.00 44.40 ? 105 VAL A C 1 ATOM 306 O O . VAL A 1 47 ? 46.648 -167.343 55.113 1.00 41.26 ? 105 VAL A O 1 ATOM 307 C CB . VAL A 1 47 ? 45.106 -164.707 54.905 1.00 41.18 ? 105 VAL A CB 1 ATOM 308 C CG1 . VAL A 1 47 ? 45.215 -164.241 56.352 1.00 42.52 ? 105 VAL A CG1 1 ATOM 309 C CG2 . VAL A 1 47 ? 44.457 -163.629 54.048 1.00 39.30 ? 105 VAL A CG2 1 ATOM 310 N N . ASP A 1 48 ? 48.179 -165.872 55.887 1.00 48.30 ? 106 ASP A N 1 ATOM 311 C CA . ASP A 1 48 ? 48.872 -166.832 56.742 1.00 48.41 ? 106 ASP A CA 1 ATOM 312 C C . ASP A 1 48 ? 49.187 -168.128 55.999 1.00 46.00 ? 106 ASP A C 1 ATOM 313 O O . ASP A 1 48 ? 48.965 -169.226 56.512 1.00 42.03 ? 106 ASP A O 1 ATOM 314 C CB . ASP A 1 48 ? 48.035 -167.126 57.989 1.00 49.05 ? 106 ASP A CB 1 ATOM 315 C CG . ASP A 1 48 ? 47.922 -165.926 58.905 1.00 57.09 ? 106 ASP A CG 1 ATOM 316 O OD1 . ASP A 1 48 ? 48.957 -165.272 59.148 1.00 59.74 ? 106 ASP A OD1 1 ATOM 317 O OD2 . ASP A 1 48 ? 46.805 -165.634 59.382 1.00 55.98 ? 106 ASP A OD2 1 ATOM 318 N N . GLY A 1 49 ? 49.693 -167.989 54.778 1.00 45.98 ? 107 GLY A N 1 ATOM 319 C CA . GLY A 1 49 ? 50.109 -169.133 53.990 1.00 54.56 ? 107 GLY A CA 1 ATOM 320 C C . GLY A 1 49 ? 48.984 -169.847 53.261 1.00 54.08 ? 107 GLY A C 1 ATOM 321 O O . GLY A 1 49 ? 49.252 -170.697 52.410 1.00 57.47 ? 107 GLY A O 1 ATOM 322 N N . THR A 1 50 ? 47.740 -169.505 53.562 1.00 54.95 ? 108 THR A N 1 ATOM 323 C CA . THR A 1 50 ? 46.588 -170.144 52.945 1.00 47.20 ? 108 THR A CA 1 ATOM 324 C C . THR A 1 50 ? 45.845 -169.256 51.945 1.00 48.19 ? 108 THR A C 1 ATOM 325 O O . THR A 1 50 ? 45.754 -168.061 52.113 1.00 36.85 ? 108 THR A O 1 ATOM 326 C CB . THR A 1 50 ? 45.609 -170.628 54.019 1.00 50.18 ? 108 THR A CB 1 ATOM 327 O OG1 . THR A 1 50 ? 46.323 -171.370 55.005 1.00 59.20 ? 108 THR A OG1 1 ATOM 328 C CG2 . THR A 1 50 ? 44.548 -171.507 53.423 1.00 48.28 ? 108 THR A CG2 1 ATOM 329 N N . LEU A 1 51 ? 45.334 -169.867 50.887 1.00 42.07 ? 109 LEU A N 1 ATOM 330 C CA . LEU A 1 51 ? 44.590 -169.146 49.862 1.00 46.61 ? 109 LEU A CA 1 ATOM 331 C C . LEU A 1 51 ? 43.102 -169.104 50.151 1.00 32.89 ? 109 LEU A C 1 ATOM 332 O O . LEU A 1 51 ? 42.508 -170.093 50.516 1.00 32.57 ? 109 LEU A O 1 ATOM 333 C CB . LEU A 1 51 ? 44.812 -169.759 48.489 1.00 44.19 ? 109 LEU A CB 1 ATOM 334 C CG . LEU A 1 51 ? 46.048 -169.315 47.717 1.00 51.59 ? 109 LEU A CG 1 ATOM 335 C CD1 . LEU A 1 51 ? 45.901 -169.724 46.269 1.00 60.26 ? 109 LEU A CD1 1 ATOM 336 C CD2 . LEU A 1 51 ? 46.250 -167.821 47.817 1.00 50.95 ? 109 LEU A CD2 1 ATOM 337 N N . TYR A 1 52 ? 42.511 -167.938 49.986 1.00 33.13 ? 110 TYR A N 1 ATOM 338 C CA . TYR A 1 52 ? 41.093 -167.775 50.224 1.00 32.64 ? 110 TYR A CA 1 ATOM 339 C C . TYR A 1 52 ? 40.434 -167.065 49.061 1.00 30.51 ? 110 TYR A C 1 ATOM 340 O O . TYR A 1 52 ? 41.050 -166.247 48.398 1.00 29.00 ? 110 TYR A O 1 ATOM 341 C CB . TYR A 1 52 ? 40.852 -167.000 51.515 1.00 23.83 ? 110 TYR A CB 1 ATOM 342 C CG . TYR A 1 52 ? 41.371 -167.701 52.730 1.00 27.57 ? 110 TYR A CG 1 ATOM 343 C CD1 . TYR A 1 52 ? 40.609 -168.638 53.377 1.00 33.84 ? 110 TYR A CD1 1 ATOM 344 C CD2 . TYR A 1 52 ? 42.625 -167.434 53.218 1.00 32.59 ? 110 TYR A CD2 1 ATOM 345 C CE1 . TYR A 1 52 ? 41.078 -169.294 54.480 1.00 32.71 ? 110 TYR A CE1 1 ATOM 346 C CE2 . TYR A 1 52 ? 43.107 -168.087 54.318 1.00 35.47 ? 110 TYR A CE2 1 ATOM 347 C CZ . TYR A 1 52 ? 42.328 -169.017 54.939 1.00 34.56 ? 110 TYR A CZ 1 ATOM 348 O OH . TYR A 1 52 ? 42.799 -169.666 56.029 1.00 47.59 ? 110 TYR A OH 1 ATOM 349 N N . ARG A 1 53 ? 39.173 -167.377 48.827 1.00 28.20 ? 111 ARG A N 1 ATOM 350 C CA . ARG A 1 53 ? 38.435 -166.741 47.743 1.00 34.66 ? 111 ARG A CA 1 ATOM 351 C C . ARG A 1 53 ? 37.913 -165.383 48.191 1.00 32.71 ? 111 ARG A C 1 ATOM 352 O O . ARG A 1 53 ? 37.547 -165.201 49.353 1.00 35.00 ? 111 ARG A O 1 ATOM 353 C CB . ARG A 1 53 ? 37.279 -167.628 47.278 1.00 24.12 ? 111 ARG A CB 1 ATOM 354 C CG . ARG A 1 53 ? 37.714 -169.008 46.809 1.00 28.79 ? 111 ARG A CG 1 ATOM 355 C CD . ARG A 1 53 ? 36.615 -169.695 46.017 1.00 25.65 ? 111 ARG A CD 1 ATOM 356 N NE . ARG A 1 53 ? 36.467 -169.119 44.683 1.00 24.22 ? 111 ARG A NE 1 ATOM 357 C CZ . ARG A 1 53 ? 35.504 -169.448 43.828 1.00 27.11 ? 111 ARG A CZ 1 ATOM 358 N NH1 . ARG A 1 53 ? 34.591 -170.352 44.163 1.00 30.02 ? 111 ARG A NH1 1 ATOM 359 N NH2 . ARG A 1 53 ? 35.450 -168.870 42.638 1.00 25.02 ? 111 ARG A NH2 1 ATOM 360 N N . GLU A 1 54 ? 37.882 -164.436 47.260 1.00 24.32 ? 112 GLU A N 1 ATOM 361 C CA . GLU A 1 54 ? 37.541 -163.055 47.568 1.00 26.96 ? 112 GLU A CA 1 ATOM 362 C C . GLU A 1 54 ? 36.639 -162.447 46.490 1.00 27.43 ? 112 GLU A C 1 ATOM 363 O O . GLU A 1 54 ? 36.959 -162.526 45.300 1.00 23.71 ? 112 GLU A O 1 ATOM 364 C CB . GLU A 1 54 ? 38.820 -162.232 47.704 1.00 25.43 ? 112 GLU A CB 1 ATOM 365 C CG . GLU A 1 54 ? 38.614 -160.807 48.190 1.00 30.02 ? 112 GLU A CG 1 ATOM 366 C CD . GLU A 1 54 ? 39.830 -159.936 47.941 1.00 33.92 ? 112 GLU A CD 1 ATOM 367 O OE1 . GLU A 1 54 ? 40.487 -160.112 46.893 1.00 28.07 ? 112 GLU A OE1 1 ATOM 368 O OE2 . GLU A 1 54 ? 40.135 -159.074 48.790 1.00 29.42 ? 112 GLU A OE2 1 ATOM 369 N N . PRO A 1 55 ? 35.507 -161.842 46.899 1.00 23.86 ? 113 PRO A N 1 ATOM 370 C CA . PRO A 1 55 ? 34.698 -161.077 45.942 1.00 19.66 ? 113 PRO A CA 1 ATOM 371 C C . PRO A 1 55 ? 35.517 -159.960 45.304 1.00 21.39 ? 113 PRO A C 1 ATOM 372 O O . PRO A 1 55 ? 36.329 -159.346 45.997 1.00 24.75 ? 113 PRO A O 1 ATOM 373 C CB . PRO A 1 55 ? 33.565 -160.515 46.807 1.00 18.31 ? 113 PRO A CB 1 ATOM 374 C CG . PRO A 1 55 ? 33.472 -161.445 47.957 1.00 21.50 ? 113 PRO A CG 1 ATOM 375 C CD . PRO A 1 55 ? 34.876 -161.886 48.229 1.00 20.60 ? 113 PRO A CD 1 ATOM 376 N N . ALA A 1 56 ? 35.305 -159.704 44.014 1.00 23.63 ? 114 ALA A N 1 ATOM 377 C CA . ALA A 1 56 ? 36.192 -158.826 43.249 1.00 21.56 ? 114 ALA A CA 1 ATOM 378 C C . ALA A 1 56 ? 35.458 -157.926 42.253 1.00 19.59 ? 114 ALA A C 1 ATOM 379 O O . ALA A 1 56 ? 36.079 -157.085 41.601 1.00 23.27 ? 114 ALA A O 1 ATOM 380 C CB . ALA A 1 56 ? 37.222 -159.667 42.514 1.00 24.22 ? 114 ALA A CB 1 ATOM 381 N N . GLY A 1 57 ? 34.146 -158.099 42.136 1.00 19.71 ? 115 GLY A N 1 ATOM 382 C CA . GLY A 1 57 ? 33.354 -157.326 41.195 1.00 20.52 ? 115 GLY A CA 1 ATOM 383 C C . GLY A 1 57 ? 33.481 -155.823 41.381 1.00 22.47 ? 115 GLY A C 1 ATOM 384 O O . GLY A 1 57 ? 33.525 -155.328 42.508 1.00 22.35 ? 115 GLY A O 1 ATOM 385 N N . LEU A 1 58 ? 33.524 -155.099 40.266 1.00 15.60 ? 116 LEU A N 1 ATOM 386 C CA . LEU A 1 58 ? 33.729 -153.653 40.274 1.00 19.31 ? 116 LEU A CA 1 ATOM 387 C C . LEU A 1 58 ? 32.432 -152.848 40.261 1.00 21.03 ? 116 LEU A C 1 ATOM 388 O O . LEU A 1 58 ? 32.456 -151.631 40.443 1.00 24.86 ? 116 LEU A O 1 ATOM 389 C CB . LEU A 1 58 ? 34.574 -153.248 39.068 1.00 19.54 ? 116 LEU A CB 1 ATOM 390 C CG . LEU A 1 58 ? 36.087 -153.128 39.245 1.00 35.16 ? 116 LEU A CG 1 ATOM 391 C CD1 . LEU A 1 58 ? 36.646 -154.299 40.015 1.00 30.17 ? 116 LEU A CD1 1 ATOM 392 C CD2 . LEU A 1 58 ? 36.743 -153.035 37.877 1.00 31.11 ? 116 LEU A CD2 1 ATOM 393 N N . CYS A 1 59 ? 31.308 -153.518 40.028 1.00 19.39 ? 117 CYS A N 1 ATOM 394 C CA . CYS A 1 59 ? 30.013 -152.843 39.989 1.00 16.88 ? 117 CYS A CA 1 ATOM 395 C C . CYS A 1 59 ? 29.186 -153.179 41.225 1.00 18.21 ? 117 CYS A C 1 ATOM 396 O O . CYS A 1 59 ? 29.200 -154.318 41.688 1.00 15.06 ? 117 CYS A O 1 ATOM 397 C CB . CYS A 1 59 ? 29.236 -153.227 38.725 1.00 20.15 ? 117 CYS A CB 1 ATOM 398 S SG . CYS A 1 59 ? 29.863 -152.472 37.202 1.00 37.84 ? 117 CYS A SG 1 ATOM 399 N N . PRO A 1 60 ? 28.461 -152.188 41.769 1.00 16.18 ? 118 PRO A N 1 ATOM 400 C CA . PRO A 1 60 ? 27.529 -152.496 42.856 1.00 18.92 ? 118 PRO A CA 1 ATOM 401 C C . PRO A 1 60 ? 26.327 -153.282 42.343 1.00 21.09 ? 118 PRO A C 1 ATOM 402 O O . PRO A 1 60 ? 25.896 -153.054 41.214 1.00 14.89 ? 118 PRO A O 1 ATOM 403 C CB . PRO A 1 60 ? 27.112 -151.114 43.365 1.00 19.07 ? 118 PRO A CB 1 ATOM 404 C CG . PRO A 1 60 ? 27.268 -150.222 42.192 1.00 20.47 ? 118 PRO A CG 1 ATOM 405 C CD . PRO A 1 60 ? 28.426 -150.760 41.403 1.00 23.47 ? 118 PRO A CD 1 ATOM 406 N N . ILE A 1 61 ? 25.806 -154.197 43.155 1.00 16.01 ? 119 ILE A N 1 ATOM 407 C CA . ILE A 1 61 ? 24.646 -154.998 42.776 1.00 11.37 ? 119 ILE A CA 1 ATOM 408 C C . ILE A 1 61 ? 23.414 -154.523 43.539 1.00 8.53 ? 119 ILE A C 1 ATOM 409 O O . ILE A 1 61 ? 23.279 -154.752 44.739 1.00 14.70 ? 119 ILE A O 1 ATOM 410 C CB . ILE A 1 61 ? 24.881 -156.495 43.041 1.00 13.08 ? 119 ILE A CB 1 ATOM 411 C CG1 . ILE A 1 61 ? 26.260 -156.918 42.522 1.00 12.80 ? 119 ILE A CG1 1 ATOM 412 C CG2 . ILE A 1 61 ? 23.780 -157.332 42.397 1.00 13.30 ? 119 ILE A CG2 1 ATOM 413 C CD1 . ILE A 1 61 ? 26.487 -156.652 41.040 1.00 20.23 ? 119 ILE A CD1 1 ATOM 414 N N . TRP A 1 62 ? 22.514 -153.865 42.819 1.00 11.74 ? 120 TRP A N 1 ATOM 415 C CA . TRP A 1 62 ? 21.362 -153.209 43.420 1.00 14.95 ? 120 TRP A CA 1 ATOM 416 C C . TRP A 1 62 ? 20.268 -154.194 43.815 1.00 18.10 ? 120 TRP A C 1 ATOM 417 O O . TRP A 1 62 ? 19.758 -154.937 42.974 1.00 15.22 ? 120 TRP A O 1 ATOM 418 C CB . TRP A 1 62 ? 20.791 -152.177 42.447 1.00 12.27 ? 120 TRP A CB 1 ATOM 419 C CG . TRP A 1 62 ? 21.717 -151.040 42.164 1.00 13.87 ? 120 TRP A CG 1 ATOM 420 C CD1 . TRP A 1 62 ? 22.901 -151.094 41.489 1.00 14.17 ? 120 TRP A CD1 1 ATOM 421 C CD2 . TRP A 1 62 ? 21.528 -149.672 42.535 1.00 11.34 ? 120 TRP A CD2 1 ATOM 422 N NE1 . TRP A 1 62 ? 23.466 -149.844 41.423 1.00 14.39 ? 120 TRP A NE1 1 ATOM 423 C CE2 . TRP A 1 62 ? 22.641 -148.952 42.058 1.00 18.38 ? 120 TRP A CE2 1 ATOM 424 C CE3 . TRP A 1 62 ? 20.525 -148.984 43.227 1.00 12.22 ? 120 TRP A CE3 1 ATOM 425 C CZ2 . TRP A 1 62 ? 22.781 -147.580 42.252 1.00 13.79 ? 120 TRP A CZ2 1 ATOM 426 C CZ3 . TRP A 1 62 ? 20.665 -147.622 43.417 1.00 22.04 ? 120 TRP A CZ3 1 ATOM 427 C CH2 . TRP A 1 62 ? 21.786 -146.934 42.932 1.00 15.27 ? 120 TRP A CH2 1 ATOM 428 N N . GLY A 1 63 ? 19.906 -154.183 45.095 1.00 13.31 ? 121 GLY A N 1 ATOM 429 C CA . GLY A 1 63 ? 18.816 -155.000 45.598 1.00 16.05 ? 121 GLY A CA 1 ATOM 430 C C . GLY A 1 63 ? 19.236 -156.382 46.064 1.00 13.00 ? 121 GLY A C 1 ATOM 431 O O . GLY A 1 63 ? 18.428 -157.120 46.631 1.00 16.04 ? 121 GLY A O 1 ATOM 432 N N . LYS A 1 64 ? 20.494 -156.739 45.828 1.00 9.17 ? 122 LYS A N 1 ATOM 433 C CA . LYS A 1 64 ? 20.993 -158.055 46.216 1.00 12.87 ? 122 LYS A CA 1 ATOM 434 C C . LYS A 1 64 ? 21.104 -158.179 47.727 1.00 14.71 ? 122 LYS A C 1 ATOM 435 O O . LYS A 1 64 ? 21.720 -157.336 48.382 1.00 19.51 ? 122 LYS A O 1 ATOM 436 C CB . LYS A 1 64 ? 22.358 -158.329 45.582 1.00 15.67 ? 122 LYS A CB 1 ATOM 437 C CG . LYS A 1 64 ? 23.079 -159.542 46.164 1.00 13.32 ? 122 LYS A CG 1 ATOM 438 C CD . LYS A 1 64 ? 24.348 -159.881 45.396 1.00 9.82 ? 122 LYS A CD 1 ATOM 439 C CE . LYS A 1 64 ? 25.100 -161.011 46.071 1.00 15.73 ? 122 LYS A CE 1 ATOM 440 N NZ . LYS A 1 64 ? 26.260 -161.483 45.272 1.00 19.86 ? 122 LYS A NZ 1 ATOM 441 N N . HIS A 1 65 ? 20.506 -159.230 48.279 1.00 17.41 ? 123 HIS A N 1 ATOM 442 C CA . HIS A 1 65 ? 20.720 -159.551 49.687 1.00 16.27 ? 123 HIS A CA 1 ATOM 443 C C . HIS A 1 65 ? 20.848 -161.058 49.864 1.00 20.05 ? 123 HIS A C 1 ATOM 444 O O . HIS A 1 65 ? 20.480 -161.821 48.975 1.00 18.51 ? 123 HIS A O 1 ATOM 445 C CB . HIS A 1 65 ? 19.584 -158.998 50.548 1.00 13.55 ? 123 HIS A CB 1 ATOM 446 C CG . HIS A 1 65 ? 18.219 -159.402 50.087 1.00 15.02 ? 123 HIS A CG 1 ATOM 447 N ND1 . HIS A 1 65 ? 17.668 -158.957 48.904 1.00 22.03 ? 123 HIS A ND1 1 ATOM 448 C CD2 . HIS A 1 65 ? 17.288 -160.203 50.657 1.00 21.27 ? 123 HIS A CD2 1 ATOM 449 C CE1 . HIS A 1 65 ? 16.459 -159.471 48.762 1.00 19.38 ? 123 HIS A CE1 1 ATOM 450 N NE2 . HIS A 1 65 ? 16.204 -160.230 49.813 1.00 23.99 ? 123 HIS A NE2 1 ATOM 451 N N . ILE A 1 66 ? 21.391 -161.485 50.999 1.00 20.20 ? 124 ILE A N 1 ATOM 452 C CA . ILE A 1 66 ? 21.516 -162.910 51.283 1.00 14.65 ? 124 ILE A CA 1 ATOM 453 C C . ILE A 1 66 ? 20.370 -163.368 52.174 1.00 16.85 ? 124 ILE A C 1 ATOM 454 O O . ILE A 1 66 ? 20.287 -162.987 53.342 1.00 18.02 ? 124 ILE A O 1 ATOM 455 C CB . ILE A 1 66 ? 22.852 -163.249 51.961 1.00 16.49 ? 124 ILE A CB 1 ATOM 456 C CG1 . ILE A 1 66 ? 24.015 -162.585 51.220 1.00 13.80 ? 124 ILE A CG1 1 ATOM 457 C CG2 . ILE A 1 66 ? 23.045 -164.763 52.018 1.00 19.10 ? 124 ILE A CG2 1 ATOM 458 C CD1 . ILE A 1 66 ? 24.109 -162.947 49.750 1.00 21.61 ? 124 ILE A CD1 1 ATOM 459 N N . GLU A 1 67 ? 19.482 -164.178 51.608 1.00 17.42 ? 125 GLU A N 1 ATOM 460 C CA . GLU A 1 67 ? 18.382 -164.744 52.368 1.00 19.45 ? 125 GLU A CA 1 ATOM 461 C C . GLU A 1 67 ? 18.905 -165.932 53.168 1.00 15.49 ? 125 GLU A C 1 ATOM 462 O O . GLU A 1 67 ? 19.574 -166.810 52.613 1.00 19.41 ? 125 GLU A O 1 ATOM 463 C CB . GLU A 1 67 ? 17.239 -165.173 51.444 1.00 21.04 ? 125 GLU A CB 1 ATOM 464 C CG . GLU A 1 67 ? 16.000 -165.677 52.175 1.00 32.29 ? 125 GLU A CG 1 ATOM 465 C CD . GLU A 1 67 ? 14.958 -166.258 51.234 1.00 51.09 ? 125 GLU A CD 1 ATOM 466 O OE1 . GLU A 1 67 ? 13.751 -166.055 51.482 1.00 70.91 ? 125 GLU A OE1 1 ATOM 467 O OE2 . GLU A 1 67 ? 15.345 -166.924 50.251 1.00 42.01 ? 125 GLU A OE2 1 ATOM 468 N N . LEU A 1 68 ? 18.611 -165.930 54.468 1.00 20.42 ? 126 LEU A N 1 ATOM 469 C CA . LEU A 1 68 ? 19.020 -166.996 55.380 1.00 25.86 ? 126 LEU A CA 1 ATOM 470 C C . LEU A 1 68 ? 17.848 -167.920 55.685 1.00 18.91 ? 126 LEU A C 1 ATOM 471 O O . LEU A 1 68 ? 16.689 -167.531 55.533 1.00 20.08 ? 126 LEU A O 1 ATOM 472 C CB . LEU A 1 68 ? 19.557 -166.419 56.692 1.00 15.37 ? 126 LEU A CB 1 ATOM 473 C CG . LEU A 1 68 ? 20.505 -165.222 56.617 1.00 20.19 ? 126 LEU A CG 1 ATOM 474 C CD1 . LEU A 1 68 ? 21.002 -164.875 58.007 1.00 18.92 ? 126 LEU A CD1 1 ATOM 475 C CD2 . LEU A 1 68 ? 21.670 -165.495 55.684 1.00 19.77 ? 126 LEU A CD2 1 ATOM 476 N N . GLN A 1 69 ? 18.156 -169.134 56.136 1.00 23.53 ? 127 GLN A N 1 ATOM 477 C CA . GLN A 1 69 ? 17.127 -170.100 56.508 1.00 22.36 ? 127 GLN A CA 1 ATOM 478 C C . GLN A 1 69 ? 17.359 -170.648 57.915 1.00 23.11 ? 127 GLN A C 1 ATOM 479 O O . GLN A 1 69 ? 17.471 -171.857 58.120 1.00 20.67 ? 127 GLN A O 1 ATOM 480 C CB . GLN A 1 69 ? 17.076 -171.237 55.485 1.00 24.38 ? 127 GLN A CB 1 ATOM 481 C CG . GLN A 1 69 ? 16.475 -170.818 54.147 1.00 28.94 ? 127 GLN A CG 1 ATOM 482 C CD . GLN A 1 69 ? 16.509 -171.929 53.116 1.00 43.22 ? 127 GLN A CD 1 ATOM 483 O OE1 . GLN A 1 69 ? 17.573 -172.301 52.622 1.00 50.14 ? 127 GLN A OE1 1 ATOM 484 N NE2 . GLN A 1 69 ? 15.339 -172.467 52.788 1.00 40.52 ? 127 GLN A NE2 1 ATOM 485 N N . GLN A 1 70 ? 17.432 -169.738 58.880 1.00 22.90 ? 128 GLN A N 1 ATOM 486 C CA . GLN A 1 70 ? 17.509 -170.103 60.288 1.00 19.72 ? 128 GLN A CA 1 ATOM 487 C C . GLN A 1 70 ? 16.119 -170.467 60.799 1.00 24.82 ? 128 GLN A C 1 ATOM 488 O O . GLN A 1 70 ? 15.124 -170.157 60.147 1.00 22.37 ? 128 GLN A O 1 ATOM 489 C CB . GLN A 1 70 ? 18.084 -168.948 61.111 1.00 19.62 ? 128 GLN A CB 1 ATOM 490 C CG . GLN A 1 70 ? 19.498 -168.542 60.724 1.00 14.63 ? 128 GLN A CG 1 ATOM 491 C CD . GLN A 1 70 ? 19.913 -167.219 61.339 1.00 21.88 ? 128 GLN A CD 1 ATOM 492 O OE1 . GLN A 1 70 ? 19.098 -166.308 61.490 1.00 22.07 ? 128 GLN A OE1 1 ATOM 493 N NE2 . GLN A 1 70 ? 21.185 -167.109 61.703 1.00 19.03 ? 128 GLN A NE2 1 ATOM 494 N N . PRO A 1 71 ? 16.041 -171.127 61.968 1.00 24.82 ? 129 PRO A N 1 ATOM 495 C CA . PRO A 1 71 ? 14.734 -171.387 62.585 1.00 28.73 ? 129 PRO A CA 1 ATOM 496 C C . PRO A 1 71 ? 13.966 -170.094 62.862 1.00 30.48 ? 129 PRO A C 1 ATOM 497 O O . PRO A 1 71 ? 14.591 -169.046 63.029 1.00 29.90 ? 129 PRO A O 1 ATOM 498 C CB . PRO A 1 71 ? 15.093 -172.100 63.895 1.00 23.52 ? 129 PRO A CB 1 ATOM 499 C CG . PRO A 1 71 ? 16.454 -172.663 63.672 1.00 25.85 ? 129 PRO A CG 1 ATOM 500 C CD . PRO A 1 71 ? 17.147 -171.704 62.753 1.00 22.97 ? 129 PRO A CD 1 ATOM 501 N N . ASP A 1 72 ? 12.638 -170.169 62.904 1.00 31.13 ? 130 ASP A N 1 ATOM 502 C CA . ASP A 1 72 ? 11.806 -168.999 63.175 1.00 43.02 ? 130 ASP A CA 1 ATOM 503 C C . ASP A 1 72 ? 11.484 -168.898 64.659 1.00 46.00 ? 130 ASP A C 1 ATOM 504 O O . ASP A 1 72 ? 10.321 -168.815 65.053 1.00 52.92 ? 130 ASP A O 1 ATOM 505 C CB . ASP A 1 72 ? 10.514 -169.053 62.356 1.00 48.97 ? 130 ASP A CB 1 ATOM 506 C CG . ASP A 1 72 ? 10.766 -168.951 60.864 1.00 70.23 ? 130 ASP A CG 1 ATOM 507 O OD1 . ASP A 1 72 ? 11.768 -168.316 60.472 1.00 75.24 ? 130 ASP A OD1 1 ATOM 508 O OD2 . ASP A 1 72 ? 9.963 -169.502 60.083 1.00 90.91 ? 130 ASP A OD2 1 ATOM 509 N N . ARG A 1 73 ? 12.531 -168.909 65.477 1.00 40.56 ? 131 ARG A N 1 ATOM 510 C CA . ARG A 1 73 ? 12.390 -168.758 66.918 1.00 36.90 ? 131 ARG A CA 1 ATOM 511 C C . ARG A 1 73 ? 13.517 -167.880 67.440 1.00 29.15 ? 131 ARG A C 1 ATOM 512 O O . ARG A 1 73 ? 14.581 -167.812 66.825 1.00 28.61 ? 131 ARG A O 1 ATOM 513 C CB . ARG A 1 73 ? 12.412 -170.121 67.617 1.00 42.58 ? 131 ARG A CB 1 ATOM 514 C CG . ARG A 1 73 ? 13.766 -170.832 67.562 1.00 41.36 ? 131 ARG A CG 1 ATOM 515 C CD . ARG A 1 73 ? 13.739 -172.160 68.296 1.00 49.17 ? 131 ARG A CD 1 ATOM 516 N NE . ARG A 1 73 ? 13.297 -173.255 67.437 1.00 76.33 ? 131 ARG A NE 1 ATOM 517 C CZ . ARG A 1 73 ? 12.913 -174.447 67.882 1.00 108.87 ? 131 ARG A CZ 1 ATOM 518 N NH1 . ARG A 1 73 ? 12.531 -175.383 67.023 1.00 93.96 ? 131 ARG A NH1 1 ATOM 519 N NH2 . ARG A 1 73 ? 12.902 -174.704 69.184 1.00 97.55 ? 131 ARG A NH2 1 ATOM 520 N N . PRO A 1 74 ? 13.290 -167.194 68.570 1.00 30.06 ? 132 PRO A N 1 ATOM 521 C CA . PRO A 1 74 ? 14.417 -166.505 69.203 1.00 30.96 ? 132 PRO A CA 1 ATOM 522 C C . PRO A 1 74 ? 15.556 -167.483 69.494 1.00 27.35 ? 132 PRO A C 1 ATOM 523 O O . PRO A 1 74 ? 15.277 -168.636 69.821 1.00 31.94 ? 132 PRO A O 1 ATOM 524 C CB . PRO A 1 74 ? 13.809 -165.951 70.493 1.00 36.15 ? 132 PRO A CB 1 ATOM 525 C CG . PRO A 1 74 ? 12.366 -165.767 70.175 1.00 36.63 ? 132 PRO A CG 1 ATOM 526 C CD . PRO A 1 74 ? 12.007 -166.878 69.225 1.00 36.39 ? 132 PRO A CD 1 ATOM 527 N N . PRO A 1 75 ? 16.818 -167.042 69.381 1.00 22.21 ? 133 PRO A N 1 ATOM 528 C CA . PRO A 1 75 ? 17.296 -165.691 69.073 1.00 27.88 ? 133 PRO A CA 1 ATOM 529 C C . PRO A 1 75 ? 17.529 -165.435 67.578 1.00 38.32 ? 133 PRO A C 1 ATOM 530 O O . PRO A 1 75 ? 18.146 -164.428 67.227 1.00 30.91 ? 133 PRO A O 1 ATOM 531 C CB . PRO A 1 75 ? 18.615 -165.630 69.838 1.00 32.42 ? 133 PRO A CB 1 ATOM 532 C CG . PRO A 1 75 ? 19.146 -167.028 69.722 1.00 31.42 ? 133 PRO A CG 1 ATOM 533 C CD . PRO A 1 75 ? 17.941 -167.947 69.683 1.00 31.72 ? 133 PRO A CD 1 ATOM 534 N N . TYR A 1 76 ? 17.041 -166.323 66.715 1.00 27.74 ? 134 TYR A N 1 ATOM 535 C CA . TYR A 1 76 ? 17.276 -166.198 65.277 1.00 29.44 ? 134 TYR A CA 1 ATOM 536 C C . TYR A 1 76 ? 16.417 -165.093 64.665 1.00 24.24 ? 134 TYR A C 1 ATOM 537 O O . TYR A 1 76 ? 15.222 -164.996 64.947 1.00 26.55 ? 134 TYR A O 1 ATOM 538 C CB . TYR A 1 76 ? 17.002 -167.530 64.571 1.00 19.39 ? 134 TYR A CB 1 ATOM 539 C CG . TYR A 1 76 ? 17.869 -168.666 65.065 1.00 22.39 ? 134 TYR A CG 1 ATOM 540 C CD1 . TYR A 1 76 ? 19.162 -168.831 64.592 1.00 18.58 ? 134 TYR A CD1 1 ATOM 541 C CD2 . TYR A 1 76 ? 17.394 -169.573 66.004 1.00 24.08 ? 134 TYR A CD2 1 ATOM 542 C CE1 . TYR A 1 76 ? 19.960 -169.864 65.039 1.00 22.89 ? 134 TYR A CE1 1 ATOM 543 C CE2 . TYR A 1 76 ? 18.187 -170.613 66.457 1.00 24.46 ? 134 TYR A CE2 1 ATOM 544 C CZ . TYR A 1 76 ? 19.468 -170.752 65.971 1.00 19.18 ? 134 TYR A CZ 1 ATOM 545 O OH . TYR A 1 76 ? 20.266 -171.781 66.413 1.00 20.52 ? 134 TYR A OH 1 ATOM 546 N N . ARG A 1 77 ? 17.040 -164.270 63.824 1.00 24.34 ? 135 ARG A N 1 ATOM 547 C CA . ARG A 1 77 ? 16.376 -163.120 63.213 1.00 26.70 ? 135 ARG A CA 1 ATOM 548 C C . ARG A 1 77 ? 16.238 -163.266 61.697 1.00 25.91 ? 135 ARG A C 1 ATOM 549 O O . ARG A 1 77 ? 15.483 -162.524 61.067 1.00 27.02 ? 135 ARG A O 1 ATOM 550 C CB . ARG A 1 77 ? 17.149 -161.835 63.534 1.00 32.16 ? 135 ARG A CB 1 ATOM 551 C CG . ARG A 1 77 ? 17.408 -161.609 65.020 1.00 36.00 ? 135 ARG A CG 1 ATOM 552 C CD . ARG A 1 77 ? 16.132 -161.239 65.755 1.00 43.60 ? 135 ARG A CD 1 ATOM 553 N NE . ARG A 1 77 ? 15.688 -159.887 65.418 1.00 78.40 ? 135 ARG A NE 1 ATOM 554 C CZ . ARG A 1 77 ? 14.417 -159.506 65.308 1.00 79.98 ? 135 ARG A CZ 1 ATOM 555 N NH1 . ARG A 1 77 ? 13.426 -160.368 65.498 1.00 81.11 ? 135 ARG A NH1 1 ATOM 556 N NH2 . ARG A 1 77 ? 14.135 -158.248 64.999 1.00 68.17 ? 135 ARG A NH2 1 ATOM 557 N N . ASN A 1 78 ? 16.962 -164.223 61.119 1.00 22.44 ? 136 ASN A N 1 ATOM 558 C CA . ASN A 1 78 ? 16.992 -164.409 59.667 1.00 22.19 ? 136 ASN A CA 1 ATOM 559 C C . ASN A 1 78 ? 17.271 -163.095 58.931 1.00 21.66 ? 136 ASN A C 1 ATOM 560 O O . ASN A 1 78 ? 16.492 -162.655 58.085 1.00 20.41 ? 136 ASN A O 1 ATOM 561 C CB . ASN A 1 78 ? 15.679 -165.028 59.179 1.00 21.57 ? 136 ASN A CB 1 ATOM 562 C CG . ASN A 1 78 ? 15.656 -166.535 59.340 1.00 27.03 ? 136 ASN A CG 1 ATOM 563 O OD1 . ASN A 1 78 ? 16.411 -167.247 58.681 1.00 23.54 ? 136 ASN A OD1 1 ATOM 564 N ND2 . ASN A 1 78 ? 14.788 -167.028 60.216 1.00 34.65 ? 136 ASN A ND2 1 ATOM 565 N N . ASN A 1 79 ? 18.396 -162.479 59.273 1.00 19.20 ? 137 ASN A N 1 ATOM 566 C CA . ASN A 1 79 ? 18.798 -161.199 58.703 1.00 16.20 ? 137 ASN A CA 1 ATOM 567 C C . ASN A 1 79 ? 20.318 -161.145 58.614 1.00 14.02 ? 137 ASN A C 1 ATOM 568 O O . ASN A 1 79 ? 21.001 -161.096 59.636 1.00 16.90 ? 137 ASN A O 1 ATOM 569 C CB . ASN A 1 79 ? 18.252 -160.052 59.558 1.00 20.82 ? 137 ASN A CB 1 ATOM 570 C CG . ASN A 1 79 ? 18.631 -158.680 59.027 1.00 22.96 ? 137 ASN A CG 1 ATOM 571 O OD1 . ASN A 1 79 ? 19.278 -158.549 57.988 1.00 18.03 ? 137 ASN A OD1 1 ATOM 572 N ND2 . ASN A 1 79 ? 18.218 -157.645 59.746 1.00 26.38 ? 137 ASN A ND2 1 ATOM 573 N N . PHE A 1 80 ? 20.849 -161.158 57.393 1.00 18.34 ? 138 PHE A N 1 ATOM 574 C CA . PHE A 1 80 ? 22.290 -161.292 57.211 1.00 16.20 ? 138 PHE A CA 1 ATOM 575 C C . PHE A 1 80 ? 23.053 -160.044 57.660 1.00 13.49 ? 138 PHE A C 1 ATOM 576 O O . PHE A 1 80 ? 24.276 -160.079 57.786 1.00 15.48 ? 138 PHE A O 1 ATOM 577 C CB . PHE A 1 80 ? 22.626 -161.640 55.747 1.00 15.48 ? 138 PHE A CB 1 ATOM 578 C CG . PHE A 1 80 ? 22.537 -160.481 54.778 1.00 15.55 ? 138 PHE A CG 1 ATOM 579 C CD1 . PHE A 1 80 ? 21.403 -159.688 54.704 1.00 14.53 ? 138 PHE A CD1 1 ATOM 580 C CD2 . PHE A 1 80 ? 23.590 -160.213 53.914 1.00 14.43 ? 138 PHE A CD2 1 ATOM 581 C CE1 . PHE A 1 80 ? 21.329 -158.640 53.799 1.00 13.40 ? 138 PHE A CE1 1 ATOM 582 C CE2 . PHE A 1 80 ? 23.522 -159.167 53.009 1.00 19.91 ? 138 PHE A CE2 1 ATOM 583 C CZ . PHE A 1 80 ? 22.389 -158.378 52.952 1.00 12.28 ? 138 PHE A CZ 1 ATOM 584 N N . LEU A 1 81 ? 22.339 -158.958 57.941 1.00 13.75 ? 139 LEU A N 1 ATOM 585 C CA . LEU A 1 81 ? 22.989 -157.741 58.421 1.00 17.37 ? 139 LEU A CA 1 ATOM 586 C C . LEU A 1 81 ? 23.161 -157.750 59.944 1.00 15.09 ? 139 LEU A C 1 ATOM 587 O O . LEU A 1 81 ? 23.792 -156.856 60.504 1.00 16.85 ? 139 LEU A O 1 ATOM 588 C CB . LEU A 1 81 ? 22.203 -156.504 57.978 1.00 13.61 ? 139 LEU A CB 1 ATOM 589 C CG . LEU A 1 81 ? 22.151 -156.260 56.463 1.00 20.39 ? 139 LEU A CG 1 ATOM 590 C CD1 . LEU A 1 81 ? 21.460 -154.942 56.157 1.00 25.81 ? 139 LEU A CD1 1 ATOM 591 C CD2 . LEU A 1 81 ? 23.538 -156.278 55.832 1.00 22.63 ? 139 LEU A CD2 1 ATOM 592 N N . GLU A 1 82 ? 22.614 -158.763 60.612 1.00 14.57 ? 140 GLU A N 1 ATOM 593 C CA . GLU A 1 82 ? 22.876 -158.954 62.036 1.00 16.43 ? 140 GLU A CA 1 ATOM 594 C C . GLU A 1 82 ? 24.346 -159.295 62.236 1.00 14.60 ? 140 GLU A C 1 ATOM 595 O O . GLU A 1 82 ? 24.970 -159.886 61.357 1.00 13.25 ? 140 GLU A O 1 ATOM 596 C CB . GLU A 1 82 ? 21.997 -160.063 62.615 1.00 22.28 ? 140 GLU A CB 1 ATOM 597 C CG . GLU A 1 82 ? 20.518 -159.726 62.678 0.83 24.00 ? 140 GLU A CG 1 ATOM 598 C CD . GLU A 1 82 ? 20.186 -158.713 63.758 0.51 30.81 ? 140 GLU A CD 1 ATOM 599 O OE1 . GLU A 1 82 ? 19.137 -158.046 63.639 0.67 34.69 ? 140 GLU A OE1 1 ATOM 600 O OE2 . GLU A 1 82 ? 20.964 -158.588 64.728 0.59 34.31 ? 140 GLU A OE2 1 ATOM 601 N N . ASP A 1 83 ? 24.895 -158.916 63.387 1.00 19.88 ? 141 ASP A N 1 ATOM 602 C CA . ASP A 1 83 ? 26.277 -159.246 63.729 1.00 15.64 ? 141 ASP A CA 1 ATOM 603 C C . ASP A 1 83 ? 26.544 -160.742 63.635 1.00 20.59 ? 141 ASP A C 1 ATOM 604 O O . ASP A 1 83 ? 25.658 -161.557 63.891 1.00 12.68 ? 141 ASP A O 1 ATOM 605 C CB . ASP A 1 83 ? 26.611 -158.774 65.150 1.00 22.19 ? 141 ASP A CB 1 ATOM 606 C CG . ASP A 1 83 ? 26.730 -157.265 65.260 1.00 34.09 ? 141 ASP A CG 1 ATOM 607 O OD1 . ASP A 1 83 ? 27.034 -156.603 64.245 1.00 30.17 ? 141 ASP A OD1 1 ATOM 608 O OD2 . ASP A 1 83 ? 26.529 -156.744 66.376 1.00 31.56 ? 141 ASP A OD2 1 ATOM 609 N N . VAL A 1 84 ? 27.770 -161.097 63.268 1.00 18.58 ? 142 VAL A N 1 ATOM 610 C CA . VAL A 1 84 ? 28.215 -162.477 63.370 1.00 21.16 ? 142 VAL A CA 1 ATOM 611 C C . VAL A 1 84 ? 28.190 -162.877 64.842 1.00 20.51 ? 142 VAL A C 1 ATOM 612 O O . VAL A 1 84 ? 28.456 -162.051 65.712 1.00 23.04 ? 142 VAL A O 1 ATOM 613 C CB . VAL A 1 84 ? 29.632 -162.679 62.796 1.00 17.80 ? 142 VAL A CB 1 ATOM 614 C CG1 . VAL A 1 84 ? 29.634 -162.446 61.299 1.00 23.86 ? 142 VAL A CG1 1 ATOM 615 C CG2 . VAL A 1 84 ? 30.634 -161.762 63.489 1.00 23.05 ? 142 VAL A CG2 1 ATOM 616 N N . PRO A 1 85 ? 27.872 -164.145 65.128 1.00 23.22 ? 143 PRO A N 1 ATOM 617 C CA . PRO A 1 85 ? 27.723 -164.579 66.521 1.00 23.52 ? 143 PRO A CA 1 ATOM 618 C C . PRO A 1 85 ? 29.050 -164.745 67.255 1.00 17.83 ? 143 PRO A C 1 ATOM 619 O O . PRO A 1 85 ? 30.056 -165.109 66.647 1.00 20.15 ? 143 PRO A O 1 ATOM 620 C CB . PRO A 1 85 ? 27.020 -165.929 66.384 1.00 21.67 ? 143 PRO A CB 1 ATOM 621 C CG . PRO A 1 85 ? 27.501 -166.455 65.078 1.00 21.63 ? 143 PRO A CG 1 ATOM 622 C CD . PRO A 1 85 ? 27.650 -165.252 64.182 1.00 25.18 ? 143 PRO A CD 1 ATOM 623 N N . THR A 1 86 ? 29.041 -164.473 68.556 1.00 23.60 ? 144 THR A N 1 ATOM 624 C CA . THR A 1 86 ? 30.158 -164.831 69.417 1.00 27.36 ? 144 THR A CA 1 ATOM 625 C C . THR A 1 86 ? 30.056 -166.317 69.738 1.00 18.09 ? 144 THR A C 1 ATOM 626 O O . THR A 1 86 ? 28.995 -166.919 69.565 1.00 17.91 ? 144 THR A O 1 ATOM 627 C CB . THR A 1 86 ? 30.160 -164.025 70.724 1.00 26.16 ? 144 THR A CB 1 ATOM 628 O OG1 . THR A 1 86 ? 29.007 -164.374 71.498 1.00 23.88 ? 144 THR A OG1 1 ATOM 629 C CG2 . THR A 1 86 ? 30.146 -162.527 70.438 1.00 25.61 ? 144 THR A CG2 1 ATOM 630 N N . GLU A 1 87 ? 31.149 -166.910 70.206 1.00 23.53 ? 145 GLU A N 1 ATOM 631 C CA . GLU A 1 87 ? 31.133 -168.319 70.588 1.00 34.66 ? 145 GLU A CA 1 ATOM 632 C C . GLU A 1 87 ? 30.118 -168.554 71.708 1.00 30.19 ? 145 GLU A C 1 ATOM 633 O O . GLU A 1 87 ? 29.438 -169.582 71.744 1.00 31.59 ? 145 GLU A O 1 ATOM 634 C CB . GLU A 1 87 ? 32.529 -168.774 71.023 1.00 35.36 ? 145 GLU A CB 1 ATOM 635 C CG . GLU A 1 87 ? 32.608 -170.229 71.466 1.00 40.29 ? 145 GLU A CG 1 ATOM 636 C CD . GLU A 1 87 ? 32.026 -171.191 70.443 1.00 64.03 ? 145 GLU A CD 1 ATOM 637 O OE1 . GLU A 1 87 ? 31.442 -172.218 70.851 1.00 53.17 ? 145 GLU A OE1 1 ATOM 638 O OE2 . GLU A 1 87 ? 32.155 -170.924 69.230 1.00 60.07 ? 145 GLU A OE2 1 ATOM 639 N N . LYS A 1 88 ? 30.014 -167.582 72.607 1.00 23.78 ? 146 LYS A N 1 ATOM 640 C CA . LYS A 1 88 ? 29.072 -167.642 73.721 1.00 28.30 ? 146 LYS A CA 1 ATOM 641 C C . LYS A 1 88 ? 27.620 -167.680 73.240 1.00 33.04 ? 146 LYS A C 1 ATOM 642 O O . LYS A 1 88 ? 26.811 -168.479 73.722 1.00 22.45 ? 146 LYS A O 1 ATOM 643 C CB . LYS A 1 88 ? 29.295 -166.441 74.644 1.00 38.15 ? 146 LYS A CB 1 ATOM 644 C CG . LYS A 1 88 ? 28.387 -166.387 75.860 1.00 42.46 ? 146 LYS A CG 1 ATOM 645 C CD . LYS A 1 88 ? 28.970 -165.463 76.921 1.00 58.84 ? 146 LYS A CD 1 ATOM 646 C CE . LYS A 1 88 ? 28.061 -165.341 78.134 1.00 73.30 ? 146 LYS A CE 1 ATOM 647 N NZ . LYS A 1 88 ? 27.407 -164.003 78.212 1.00 70.60 ? 146 LYS A NZ 1 ATOM 648 N N . GLU A 1 89 ? 27.297 -166.812 72.286 1.00 24.72 ? 147 GLU A N 1 ATOM 649 C CA . GLU A 1 89 ? 25.957 -166.756 71.708 1.00 26.62 ? 147 GLU A CA 1 ATOM 650 C C . GLU A 1 89 ? 25.634 -168.053 70.977 1.00 13.94 ? 147 GLU A C 1 ATOM 651 O O . GLU A 1 89 ? 24.513 -168.562 71.051 1.00 24.22 ? 147 GLU A O 1 ATOM 652 C CB . GLU A 1 89 ? 25.841 -165.561 70.755 1.00 27.59 ? 147 GLU A CB 1 ATOM 653 C CG . GLU A 1 89 ? 25.798 -164.213 71.474 1.00 31.79 ? 147 GLU A CG 1 ATOM 654 C CD . GLU A 1 89 ? 25.980 -163.020 70.543 1.00 52.45 ? 147 GLU A CD 1 ATOM 655 O OE1 . GLU A 1 89 ? 25.568 -161.904 70.927 1.00 44.50 ? 147 GLU A OE1 1 ATOM 656 O OE2 . GLU A 1 89 ? 26.540 -163.187 69.439 1.00 29.82 ? 147 GLU A OE2 1 ATOM 657 N N . TYR A 1 90 ? 26.629 -168.578 70.270 1.00 15.76 ? 148 TYR A N 1 ATOM 658 C CA . TYR A 1 90 ? 26.492 -169.836 69.550 1.00 27.42 ? 148 TYR A CA 1 ATOM 659 C C . TYR A 1 90 ? 26.213 -170.966 70.537 1.00 30.17 ? 148 TYR A C 1 ATOM 660 O O . TYR A 1 90 ? 25.296 -171.764 70.337 1.00 24.75 ? 148 TYR A O 1 ATOM 661 C CB . TYR A 1 90 ? 27.758 -170.127 68.736 1.00 25.34 ? 148 TYR A CB 1 ATOM 662 C CG . TYR A 1 90 ? 27.708 -171.399 67.908 1.00 22.61 ? 148 TYR A CG 1 ATOM 663 C CD1 . TYR A 1 90 ? 26.502 -171.910 67.443 1.00 20.49 ? 148 TYR A CD1 1 ATOM 664 C CD2 . TYR A 1 90 ? 28.873 -172.092 67.595 1.00 27.94 ? 148 TYR A CD2 1 ATOM 665 C CE1 . TYR A 1 90 ? 26.458 -173.071 66.689 1.00 22.29 ? 148 TYR A CE1 1 ATOM 666 C CE2 . TYR A 1 90 ? 28.838 -173.254 66.841 1.00 29.32 ? 148 TYR A CE2 1 ATOM 667 C CZ . TYR A 1 90 ? 27.629 -173.739 66.392 1.00 30.90 ? 148 TYR A CZ 1 ATOM 668 O OH . TYR A 1 90 ? 27.594 -174.894 65.643 1.00 32.54 ? 148 TYR A OH 1 ATOM 669 N N . LYS A 1 91 ? 27.004 -171.027 71.606 1.00 28.26 ? 149 LYS A N 1 ATOM 670 C CA . LYS A 1 91 ? 26.765 -172.005 72.664 1.00 31.98 ? 149 LYS A CA 1 ATOM 671 C C . LYS A 1 91 ? 25.375 -171.831 73.260 1.00 32.32 ? 149 LYS A C 1 ATOM 672 O O . LYS A 1 91 ? 24.684 -172.814 73.527 1.00 29.92 ? 149 LYS A O 1 ATOM 673 C CB . LYS A 1 91 ? 27.820 -171.889 73.767 1.00 31.77 ? 149 LYS A CB 1 ATOM 674 C CG . LYS A 1 91 ? 29.184 -172.432 73.372 1.00 41.58 ? 149 LYS A CG 1 ATOM 675 C CD . LYS A 1 91 ? 30.181 -172.346 74.520 1.00 54.79 ? 149 LYS A CD 1 ATOM 676 C CE . LYS A 1 91 ? 31.577 -172.757 74.074 1.00 55.55 ? 149 LYS A CE 1 ATOM 677 N NZ . LYS A 1 91 ? 32.600 -172.562 75.140 1.00 64.36 ? 149 LYS A NZ 1 ATOM 678 N N . GLN A 1 92 ? 24.968 -170.584 73.473 1.00 26.04 ? 150 GLN A N 1 ATOM 679 C CA . GLN A 1 92 ? 23.647 -170.310 74.034 1.00 22.62 ? 150 GLN A CA 1 ATOM 680 C C . GLN A 1 92 ? 22.499 -170.734 73.117 1.00 30.22 ? 150 GLN A C 1 ATOM 681 O O . GLN A 1 92 ? 21.498 -171.274 73.585 1.00 23.92 ? 150 GLN A O 1 ATOM 682 C CB . GLN A 1 92 ? 23.505 -168.820 74.363 1.00 31.62 ? 150 GLN A CB 1 ATOM 683 C CG . GLN A 1 92 ? 22.128 -168.428 74.909 1.00 37.78 ? 150 GLN A CG 1 ATOM 684 C CD . GLN A 1 92 ? 21.750 -169.192 76.171 1.00 69.68 ? 150 GLN A CD 1 ATOM 685 O OE1 . GLN A 1 92 ? 22.550 -169.315 77.098 1.00 59.38 ? 150 GLN A OE1 1 ATOM 686 N NE2 . GLN A 1 92 ? 20.524 -169.714 76.208 1.00 41.51 ? 150 GLN A NE2 1 ATOM 687 N N . SER A 1 93 ? 22.622 -170.476 71.818 1.00 20.84 ? 151 SER A N 1 ATOM 688 C CA . SER A 1 93 ? 21.551 -170.829 70.890 1.00 25.08 ? 151 SER A CA 1 ATOM 689 C C . SER A 1 93 ? 21.520 -172.322 70.579 1.00 23.51 ? 151 SER A C 1 ATOM 690 O O . SER A 1 93 ? 20.450 -172.917 70.463 1.00 24.04 ? 151 SER A O 1 ATOM 691 C CB . SER A 1 93 ? 21.693 -170.045 69.580 1.00 21.30 ? 151 SER A CB 1 ATOM 692 O OG . SER A 1 93 ? 22.856 -170.437 68.873 1.00 21.73 ? 151 SER A OG 1 ATOM 693 N N . GLY A 1 94 ? 22.697 -172.923 70.446 1.00 23.92 ? 152 GLY A N 1 ATOM 694 C CA . GLY A 1 94 ? 22.805 -174.256 69.883 1.00 27.18 ? 152 GLY A CA 1 ATOM 695 C C . GLY A 1 94 ? 22.728 -174.155 68.372 1.00 25.73 ? 152 GLY A C 1 ATOM 696 O O . GLY A 1 94 ? 22.586 -173.058 67.833 1.00 27.46 ? 152 GLY A O 1 ATOM 697 N N . ASN A 1 95 ? 22.816 -175.290 67.686 1.00 24.60 ? 153 ASN A N 1 ATOM 698 C CA . ASN A 1 95 ? 22.806 -175.298 66.226 1.00 22.47 ? 153 ASN A CA 1 ATOM 699 C C . ASN A 1 95 ? 21.469 -174.836 65.648 1.00 20.15 ? 153 ASN A C 1 ATOM 700 O O . ASN A 1 95 ? 20.417 -175.118 66.219 1.00 24.60 ? 153 ASN A O 1 ATOM 701 C CB . ASN A 1 95 ? 23.126 -176.700 65.700 1.00 20.73 ? 153 ASN A CB 1 ATOM 702 C CG . ASN A 1 95 ? 24.614 -176.998 65.682 1.00 26.09 ? 153 ASN A CG 1 ATOM 703 O OD1 . ASN A 1 95 ? 25.434 -176.175 66.090 1.00 34.78 ? 153 ASN A OD1 1 ATOM 704 N ND2 . ASN A 1 95 ? 24.970 -178.186 65.205 1.00 37.91 ? 153 ASN A ND2 1 ATOM 705 N N . PRO A 1 96 ? 21.501 -174.120 64.509 1.00 20.31 ? 154 PRO A N 1 ATOM 706 C CA . PRO A 1 96 ? 22.683 -173.652 63.778 1.00 19.63 ? 154 PRO A CA 1 ATOM 707 C C . PRO A 1 96 ? 23.191 -172.313 64.306 1.00 16.86 ? 154 PRO A C 1 ATOM 708 O O . PRO A 1 96 ? 22.597 -171.756 65.228 1.00 14.78 ? 154 PRO A O 1 ATOM 709 C CB . PRO A 1 96 ? 22.167 -173.513 62.348 1.00 20.70 ? 154 PRO A CB 1 ATOM 710 C CG . PRO A 1 96 ? 20.754 -173.110 62.525 1.00 24.40 ? 154 PRO A CG 1 ATOM 711 C CD . PRO A 1 96 ? 20.261 -173.799 63.780 1.00 17.57 ? 154 PRO A CD 1 ATOM 712 N N . LEU A 1 97 ? 24.276 -171.816 63.720 1.00 16.22 ? 155 LEU A N 1 ATOM 713 C CA . LEU A 1 97 ? 24.807 -170.498 64.051 1.00 19.72 ? 155 LEU A CA 1 ATOM 714 C C . LEU A 1 97 ? 23.711 -169.434 64.055 1.00 17.55 ? 155 LEU A C 1 ATOM 715 O O . LEU A 1 97 ? 22.921 -169.359 63.116 1.00 20.57 ? 155 LEU A O 1 ATOM 716 C CB . LEU A 1 97 ? 25.891 -170.101 63.050 1.00 15.21 ? 155 LEU A CB 1 ATOM 717 C CG . LEU A 1 97 ? 27.218 -170.849 63.144 1.00 22.51 ? 155 LEU A CG 1 ATOM 718 C CD1 . LEU A 1 97 ? 28.023 -170.654 61.874 1.00 24.48 ? 155 LEU A CD1 1 ATOM 719 C CD2 . LEU A 1 97 ? 28.006 -170.372 64.349 1.00 28.06 ? 155 LEU A CD2 1 ATOM 720 N N . PRO A 1 98 ? 23.645 -168.617 65.120 1.00 17.26 ? 156 PRO A N 1 ATOM 721 C CA . PRO A 1 98 ? 22.727 -167.477 65.116 1.00 21.51 ? 156 PRO A CA 1 ATOM 722 C C . PRO A 1 98 ? 23.395 -166.249 64.508 1.00 14.62 ? 156 PRO A C 1 ATOM 723 O O . PRO A 1 98 ? 24.510 -166.362 63.994 1.00 19.85 ? 156 PRO A O 1 ATOM 724 C CB . PRO A 1 98 ? 22.426 -167.275 66.599 1.00 22.77 ? 156 PRO A CB 1 ATOM 725 C CG . PRO A 1 98 ? 23.693 -167.669 67.271 1.00 18.18 ? 156 PRO A CG 1 ATOM 726 C CD . PRO A 1 98 ? 24.322 -168.757 66.422 1.00 16.16 ? 156 PRO A CD 1 ATOM 727 N N . GLY A 1 99 ? 22.731 -165.100 64.563 1.00 21.58 ? 157 GLY A N 1 ATOM 728 C CA . GLY A 1 99 ? 23.304 -163.871 64.045 1.00 22.52 ? 157 GLY A CA 1 ATOM 729 C C . GLY A 1 99 ? 23.293 -163.816 62.528 1.00 17.81 ? 157 GLY A C 1 ATOM 730 O O . GLY A 1 99 ? 22.498 -164.497 61.880 1.00 17.50 ? 157 GLY A O 1 ATOM 731 N N . GLY A 1 100 ? 24.182 -163.000 61.964 1.00 19.84 ? 158 GLY A N 1 ATOM 732 C CA . GLY A 1 100 ? 24.249 -162.799 60.527 1.00 14.38 ? 158 GLY A CA 1 ATOM 733 C C . GLY A 1 100 ? 25.675 -162.710 60.015 1.00 14.78 ? 158 GLY A C 1 ATOM 734 O O . GLY A 1 100 ? 26.567 -163.381 60.529 1.00 14.70 ? 158 GLY A O 1 ATOM 735 N N . PHE A 1 101 ? 25.882 -161.870 59.003 1.00 12.38 ? 159 PHE A N 1 ATOM 736 C CA . PHE A 1 101 ? 27.169 -161.763 58.317 1.00 13.83 ? 159 PHE A CA 1 ATOM 737 C C . PHE A 1 101 ? 27.955 -160.516 58.716 1.00 18.62 ? 159 PHE A C 1 ATOM 738 O O . PHE A 1 101 ? 29.104 -160.347 58.309 1.00 15.55 ? 159 PHE A O 1 ATOM 739 C CB . PHE A 1 101 ? 26.969 -161.727 56.797 1.00 20.02 ? 159 PHE A CB 1 ATOM 740 C CG . PHE A 1 101 ? 26.535 -163.037 56.188 1.00 20.46 ? 159 PHE A CG 1 ATOM 741 C CD1 . PHE A 1 101 ? 26.187 -164.128 56.971 1.00 15.22 ? 159 PHE A CD1 1 ATOM 742 C CD2 . PHE A 1 101 ? 26.488 -163.169 54.810 1.00 13.66 ? 159 PHE A CD2 1 ATOM 743 C CE1 . PHE A 1 101 ? 25.796 -165.320 56.382 1.00 18.75 ? 159 PHE A CE1 1 ATOM 744 C CE2 . PHE A 1 101 ? 26.101 -164.354 54.220 1.00 13.40 ? 159 PHE A CE2 1 ATOM 745 C CZ . PHE A 1 101 ? 25.754 -165.431 55.004 1.00 20.16 ? 159 PHE A CZ 1 ATOM 746 N N . ASN A 1 102 ? 27.333 -159.635 59.491 1.00 18.93 ? 160 ASN A N 1 ATOM 747 C CA . ASN A 1 102 ? 27.908 -158.319 59.744 1.00 17.64 ? 160 ASN A CA 1 ATOM 748 C C . ASN A 1 102 ? 29.138 -158.352 60.646 1.00 20.49 ? 160 ASN A C 1 ATOM 749 O O . ASN A 1 102 ? 29.158 -159.024 61.676 1.00 21.12 ? 160 ASN A O 1 ATOM 750 C CB . ASN A 1 102 ? 26.851 -157.399 60.349 1.00 20.56 ? 160 ASN A CB 1 ATOM 751 C CG . ASN A 1 102 ? 27.338 -155.972 60.492 1.00 32.20 ? 160 ASN A CG 1 ATOM 752 O OD1 . ASN A 1 102 ? 27.463 -155.251 59.505 1.00 20.80 ? 160 ASN A OD1 1 ATOM 753 N ND2 . ASN A 1 102 ? 27.613 -155.555 61.724 1.00 24.63 ? 160 ASN A ND2 1 ATOM 754 N N . LEU A 1 103 ? 30.164 -157.617 60.233 1.00 15.87 ? 161 LEU A N 1 ATOM 755 C CA . LEU A 1 103 ? 31.404 -157.503 60.988 1.00 17.42 ? 161 LEU A CA 1 ATOM 756 C C . LEU A 1 103 ? 31.162 -156.790 62.318 1.00 26.60 ? 161 LEU A C 1 ATOM 757 O O . LEU A 1 103 ? 30.664 -155.664 62.341 1.00 24.43 ? 161 LEU A O 1 ATOM 758 C CB . LEU A 1 103 ? 32.447 -156.754 60.155 1.00 22.67 ? 161 LEU A CB 1 ATOM 759 C CG . LEU A 1 103 ? 33.807 -156.473 60.792 1.00 29.97 ? 161 LEU A CG 1 ATOM 760 C CD1 . LEU A 1 103 ? 34.541 -157.765 61.102 1.00 25.52 ? 161 LEU A CD1 1 ATOM 761 C CD2 . LEU A 1 103 ? 34.637 -155.589 59.874 1.00 26.08 ? 161 LEU A CD2 1 ATOM 762 N N . ASN A 1 104 ? 31.519 -157.447 63.420 1.00 20.75 ? 162 ASN A N 1 ATOM 763 C CA . ASN A 1 104 ? 31.224 -156.933 64.757 1.00 23.45 ? 162 ASN A CA 1 ATOM 764 C C . ASN A 1 104 ? 32.449 -156.379 65.491 1.00 23.34 ? 162 ASN A C 1 ATOM 765 O O . ASN A 1 104 ? 32.379 -156.088 66.685 1.00 28.29 ? 162 ASN A O 1 ATOM 766 C CB . ASN A 1 104 ? 30.584 -158.035 65.606 1.00 23.36 ? 162 ASN A CB 1 ATOM 767 C CG . ASN A 1 104 ? 31.554 -159.153 65.942 1.00 23.31 ? 162 ASN A CG 1 ATOM 768 O OD1 . ASN A 1 104 ? 32.542 -159.368 65.240 1.00 30.23 ? 162 ASN A OD1 1 ATOM 769 N ND2 . ASN A 1 104 ? 31.274 -159.872 67.021 1.00 31.47 ? 162 ASN A ND2 1 ATOM 770 N N . PHE A 1 105 ? 33.564 -156.229 64.780 1.00 22.41 ? 163 PHE A N 1 ATOM 771 C CA . PHE A 1 105 ? 34.803 -155.758 65.395 1.00 25.11 ? 163 PHE A CA 1 ATOM 772 C C . PHE A 1 105 ? 34.665 -154.306 65.845 1.00 24.90 ? 163 PHE A C 1 ATOM 773 O O . PHE A 1 105 ? 33.859 -153.555 65.298 1.00 23.74 ? 163 PHE A O 1 ATOM 774 C CB . PHE A 1 105 ? 35.983 -155.884 64.426 1.00 23.14 ? 163 PHE A CB 1 ATOM 775 C CG . PHE A 1 105 ? 36.380 -157.306 64.109 1.00 18.42 ? 163 PHE A CG 1 ATOM 776 C CD1 . PHE A 1 105 ? 35.572 -158.378 64.457 1.00 26.87 ? 163 PHE A CD1 1 ATOM 777 C CD2 . PHE A 1 105 ? 37.577 -157.564 63.462 1.00 20.41 ? 163 PHE A CD2 1 ATOM 778 C CE1 . PHE A 1 105 ? 35.949 -159.673 64.159 1.00 23.69 ? 163 PHE A CE1 1 ATOM 779 C CE2 . PHE A 1 105 ? 37.958 -158.857 63.164 1.00 28.07 ? 163 PHE A CE2 1 ATOM 780 C CZ . PHE A 1 105 ? 37.143 -159.912 63.512 1.00 23.83 ? 163 PHE A CZ 1 ATOM 781 N N . VAL A 1 106 ? 35.461 -153.917 66.838 1.00 22.62 ? 164 VAL A N 1 ATOM 782 C CA . VAL A 1 106 ? 35.414 -152.562 67.378 1.00 23.11 ? 164 VAL A CA 1 ATOM 783 C C . VAL A 1 106 ? 36.809 -152.002 67.641 1.00 20.89 ? 164 VAL A C 1 ATOM 784 O O . VAL A 1 106 ? 37.786 -152.744 67.734 1.00 19.89 ? 164 VAL A O 1 ATOM 785 C CB . VAL A 1 106 ? 34.605 -152.501 68.696 1.00 24.97 ? 164 VAL A CB 1 ATOM 786 C CG1 . VAL A 1 106 ? 33.154 -152.881 68.452 1.00 24.48 ? 164 VAL A CG1 1 ATOM 787 C CG2 . VAL A 1 106 ? 35.225 -153.404 69.763 1.00 25.59 ? 164 VAL A CG2 1 ATOM 788 N N . THR A 1 107 ? 36.889 -150.682 67.756 1.00 20.97 ? 165 THR A N 1 ATOM 789 C CA . THR A 1 107 ? 38.117 -150.020 68.172 1.00 24.41 ? 165 THR A CA 1 ATOM 790 C C . THR A 1 107 ? 38.384 -150.307 69.647 1.00 28.65 ? 165 THR A C 1 ATOM 791 O O . THR A 1 107 ? 37.491 -150.768 70.357 1.00 23.47 ? 165 THR A O 1 ATOM 792 C CB . THR A 1 107 ? 38.031 -148.504 67.978 1.00 19.24 ? 165 THR A CB 1 ATOM 793 O OG1 . THR A 1 107 ? 37.041 -147.973 68.868 1.00 21.47 ? 165 THR A OG1 1 ATOM 794 C CG2 . THR A 1 107 ? 37.666 -148.164 66.543 1.00 19.84 ? 165 THR A CG2 1 ATOM 795 N N . PRO A 1 108 ? 39.613 -150.029 70.116 1.00 31.25 ? 166 PRO A N 1 ATOM 796 C CA . PRO A 1 108 ? 39.935 -150.178 71.541 1.00 32.90 ? 166 PRO A CA 1 ATOM 797 C C . PRO A 1 108 ? 38.962 -149.444 72.465 1.00 23.59 ? 166 PRO A C 1 ATOM 798 O O . PRO A 1 108 ? 38.730 -149.894 73.587 1.00 34.72 ? 166 PRO A O 1 ATOM 799 C CB . PRO A 1 108 ? 41.336 -149.574 71.640 1.00 40.17 ? 166 PRO A CB 1 ATOM 800 C CG . PRO A 1 108 ? 41.935 -149.820 70.304 1.00 33.42 ? 166 PRO A CG 1 ATOM 801 C CD . PRO A 1 108 ? 40.805 -149.682 69.321 1.00 31.91 ? 166 PRO A CD 1 ATOM 802 N N . SER A 1 109 ? 38.397 -148.335 71.992 1.00 27.57 ? 167 SER A N 1 ATOM 803 C CA . SER A 1 109 ? 37.441 -147.563 72.780 1.00 25.92 ? 167 SER A CA 1 ATOM 804 C C . SER A 1 109 ? 36.017 -148.116 72.661 1.00 32.98 ? 167 SER A C 1 ATOM 805 O O . SER A 1 109 ? 35.110 -147.656 73.356 1.00 30.41 ? 167 SER A O 1 ATOM 806 C CB . SER A 1 109 ? 37.462 -146.094 72.351 1.00 27.10 ? 167 SER A CB 1 ATOM 807 O OG . SER A 1 109 ? 36.877 -145.924 71.074 1.00 29.59 ? 167 SER A OG 1 ATOM 808 N N . GLY A 1 110 ? 35.824 -149.090 71.772 1.00 30.43 ? 168 GLY A N 1 ATOM 809 C CA . GLY A 1 110 ? 34.549 -149.777 71.643 1.00 26.44 ? 168 GLY A CA 1 ATOM 810 C C . GLY A 1 110 ? 33.657 -149.294 70.511 1.00 27.00 ? 168 GLY A C 1 ATOM 811 O O . GLY A 1 110 ? 32.470 -149.618 70.476 1.00 27.69 ? 168 GLY A O 1 ATOM 812 N N . GLN A 1 111 ? 34.219 -148.527 69.582 1.00 25.76 ? 169 GLN A N 1 ATOM 813 C CA . GLN A 1 111 ? 33.451 -148.022 68.449 1.00 26.29 ? 169 GLN A CA 1 ATOM 814 C C . GLN A 1 111 ? 33.336 -149.079 67.352 1.00 20.63 ? 169 GLN A C 1 ATOM 815 O O . GLN A 1 111 ? 34.335 -149.664 66.937 1.00 20.98 ? 169 GLN A O 1 ATOM 816 C CB . GLN A 1 111 ? 34.096 -146.751 67.890 1.00 28.63 ? 169 GLN A CB 1 ATOM 817 C CG . GLN A 1 111 ? 33.477 -146.243 66.594 1.00 23.56 ? 169 GLN A CG 1 ATOM 818 C CD . GLN A 1 111 ? 32.004 -145.913 66.731 0.96 31.69 ? 169 GLN A CD 1 ATOM 819 O OE1 . GLN A 1 111 ? 31.563 -145.394 67.756 0.92 28.58 ? 169 GLN A OE1 1 ATOM 820 N NE2 . GLN A 1 111 ? 31.232 -146.214 65.692 0.89 26.83 ? 169 GLN A NE2 1 ATOM 821 N N . ARG A 1 112 ? 32.108 -149.316 66.899 1.00 27.87 ? 170 ARG A N 1 ATOM 822 C CA . ARG A 1 112 ? 31.839 -150.221 65.783 1.00 26.42 ? 170 ARG A CA 1 ATOM 823 C C . ARG A 1 112 ? 32.450 -149.732 64.480 1.00 23.02 ? 170 ARG A C 1 ATOM 824 O O . ARG A 1 112 ? 32.424 -148.538 64.185 1.00 24.02 ? 170 ARG A O 1 ATOM 825 C CB . ARG A 1 112 ? 30.334 -150.379 65.569 1.00 25.91 ? 170 ARG A CB 1 ATOM 826 C CG . ARG A 1 112 ? 29.614 -151.250 66.567 1.00 31.25 ? 170 ARG A CG 1 ATOM 827 C CD . ARG A 1 112 ? 28.121 -151.218 66.280 1.00 35.68 ? 170 ARG A CD 1 ATOM 828 N NE . ARG A 1 112 ? 27.392 -152.257 66.998 1.00 45.04 ? 170 ARG A NE 1 ATOM 829 C CZ . ARG A 1 112 ? 27.301 -153.523 66.600 1.00 54.01 ? 170 ARG A CZ 1 ATOM 830 N NH1 . ARG A 1 112 ? 27.903 -153.926 65.485 1.00 32.61 ? 170 ARG A NH1 1 ATOM 831 N NH2 . ARG A 1 112 ? 26.609 -154.391 67.325 1.00 41.86 ? 170 ARG A NH2 1 ATOM 832 N N . ILE A 1 113 ? 32.977 -150.663 63.693 1.00 20.89 ? 171 ILE A N 1 ATOM 833 C CA . ILE A 1 113 ? 33.359 -150.363 62.320 1.00 18.51 ? 171 ILE A CA 1 ATOM 834 C C . ILE A 1 113 ? 32.159 -150.598 61.403 1.00 23.07 ? 171 ILE A C 1 ATOM 835 O O . ILE A 1 113 ? 32.050 -149.981 60.346 1.00 23.60 ? 171 ILE A O 1 ATOM 836 C CB . ILE A 1 113 ? 34.557 -151.215 61.849 1.00 20.39 ? 171 ILE A CB 1 ATOM 837 C CG1 . ILE A 1 113 ? 35.013 -150.756 60.461 1.00 30.80 ? 171 ILE A CG1 1 ATOM 838 C CG2 . ILE A 1 113 ? 34.197 -152.696 61.839 1.00 30.68 ? 171 ILE A CG2 1 ATOM 839 C CD1 . ILE A 1 113 ? 36.321 -151.366 60.004 1.00 34.05 ? 171 ILE A CD1 1 ATOM 840 N N . SER A 1 114 ? 31.256 -151.484 61.817 1.00 23.36 ? 172 SER A N 1 ATOM 841 C CA . SER A 1 114 ? 30.080 -151.812 61.015 1.00 20.54 ? 172 SER A CA 1 ATOM 842 C C . SER A 1 114 ? 28.873 -152.150 61.893 1.00 18.26 ? 172 SER A C 1 ATOM 843 O O . SER A 1 114 ? 28.998 -152.933 62.834 1.00 22.40 ? 172 SER A O 1 ATOM 844 C CB . SER A 1 114 ? 30.385 -152.983 60.085 1.00 20.45 ? 172 SER A CB 1 ATOM 845 O OG . SER A 1 114 ? 29.263 -153.292 59.277 1.00 17.76 ? 172 SER A OG 1 ATOM 846 N N . PRO A 1 115 ? 27.698 -151.565 61.596 1.00 18.14 ? 173 PRO A N 1 ATOM 847 C CA . PRO A 1 115 ? 27.431 -150.563 60.557 1.00 20.84 ? 173 PRO A CA 1 ATOM 848 C C . PRO A 1 115 ? 28.094 -149.226 60.853 1.00 23.94 ? 173 PRO A C 1 ATOM 849 O O . PRO A 1 115 ? 28.373 -148.920 62.013 1.00 23.38 ? 173 PRO A O 1 ATOM 850 C CB . PRO A 1 115 ? 25.905 -150.425 60.578 1.00 21.48 ? 173 PRO A CB 1 ATOM 851 C CG . PRO A 1 115 ? 25.492 -150.896 61.920 1.00 20.94 ? 173 PRO A CG 1 ATOM 852 C CD . PRO A 1 115 ? 26.463 -151.969 62.290 1.00 23.99 ? 173 PRO A CD 1 ATOM 853 N N . PHE A 1 116 ? 28.341 -148.450 59.804 1.00 21.34 ? 174 PHE A N 1 ATOM 854 C CA . PHE A 1 116 ? 29.003 -147.158 59.927 1.00 20.25 ? 174 PHE A CA 1 ATOM 855 C C . PHE A 1 116 ? 28.150 -146.066 59.282 1.00 25.17 ? 174 PHE A C 1 ATOM 856 O O . PHE A 1 116 ? 27.763 -146.194 58.123 1.00 20.64 ? 174 PHE A O 1 ATOM 857 C CB . PHE A 1 116 ? 30.381 -147.209 59.276 1.00 18.59 ? 174 PHE A CB 1 ATOM 858 C CG . PHE A 1 116 ? 31.325 -146.162 59.779 1.00 20.17 ? 174 PHE A CG 1 ATOM 859 C CD1 . PHE A 1 116 ? 31.986 -146.335 60.983 1.00 28.10 ? 174 PHE A CD1 1 ATOM 860 C CD2 . PHE A 1 116 ? 31.555 -145.007 59.051 1.00 22.90 ? 174 PHE A CD2 1 ATOM 861 C CE1 . PHE A 1 116 ? 32.856 -145.375 61.453 1.00 25.45 ? 174 PHE A CE1 1 ATOM 862 C CE2 . PHE A 1 116 ? 32.426 -144.042 59.517 1.00 28.07 ? 174 PHE A CE2 1 ATOM 863 C CZ . PHE A 1 116 ? 33.077 -144.226 60.719 1.00 24.25 ? 174 PHE A CZ 1 ATOM 864 N N . PRO A 1 117 ? 27.855 -144.985 60.027 1.00 25.33 ? 175 PRO A N 1 ATOM 865 C CA . PRO A 1 117 ? 26.956 -143.944 59.511 1.00 20.42 ? 175 PRO A CA 1 ATOM 866 C C . PRO A 1 117 ? 27.582 -143.094 58.410 1.00 20.26 ? 175 PRO A C 1 ATOM 867 O O . PRO A 1 117 ? 28.757 -142.733 58.488 1.00 20.41 ? 175 PRO A O 1 ATOM 868 C CB . PRO A 1 117 ? 26.666 -143.094 60.747 1.00 23.27 ? 175 PRO A CB 1 ATOM 869 C CG . PRO A 1 117 ? 27.882 -143.240 61.576 1.00 27.26 ? 175 PRO A CG 1 ATOM 870 C CD . PRO A 1 117 ? 28.343 -144.656 61.378 1.00 31.39 ? 175 PRO A CD 1 ATOM 871 N N . MET A 1 118 ? 26.786 -142.767 57.399 1.00 18.88 ? 176 MET A N 1 ATOM 872 C CA . MET A 1 118 ? 27.276 -142.029 56.244 1.00 20.73 ? 176 MET A CA 1 ATOM 873 C C . MET A 1 118 ? 27.685 -140.601 56.605 1.00 22.71 ? 176 MET A C 1 ATOM 874 O O . MET A 1 118 ? 28.543 -140.017 55.947 1.00 21.19 ? 176 MET A O 1 ATOM 875 C CB . MET A 1 118 ? 26.209 -142.010 55.146 1.00 18.57 ? 176 MET A CB 1 ATOM 876 C CG . MET A 1 118 ? 26.635 -141.335 53.845 1.00 26.72 ? 176 MET A CG 1 ATOM 877 S SD . MET A 1 118 ? 28.198 -141.943 53.172 1.00 26.27 ? 176 MET A SD 1 ATOM 878 C CE . MET A 1 118 ? 27.932 -143.718 53.184 1.00 24.31 ? 176 MET A CE 1 ATOM 879 N N . GLU A 1 119 ? 27.080 -140.040 57.650 1.00 21.12 ? 177 GLU A N 1 ATOM 880 C CA . GLU A 1 119 ? 27.381 -138.667 58.048 1.00 27.89 ? 177 GLU A CA 1 ATOM 881 C C . GLU A 1 119 ? 28.843 -138.517 58.466 1.00 27.52 ? 177 GLU A C 1 ATOM 882 O O . GLU A 1 119 ? 29.445 -137.461 58.278 1.00 36.98 ? 177 GLU A O 1 ATOM 883 C CB . GLU A 1 119 ? 26.465 -138.217 59.189 1.00 23.74 ? 177 GLU A CB 1 ATOM 884 C CG . GLU A 1 119 ? 24.981 -138.168 58.824 1.00 28.64 ? 177 GLU A CG 1 ATOM 885 C CD . GLU A 1 119 ? 24.236 -139.455 59.148 1.00 34.70 ? 177 GLU A CD 1 ATOM 886 O OE1 . GLU A 1 119 ? 23.007 -139.388 59.367 1.00 28.73 ? 177 GLU A OE1 1 ATOM 887 O OE2 . GLU A 1 119 ? 24.870 -140.530 59.180 1.00 39.73 ? 177 GLU A OE2 1 ATOM 888 N N . LEU A 1 120 ? 29.410 -139.582 59.024 1.00 20.50 ? 178 LEU A N 1 ATOM 889 C CA . LEU A 1 120 ? 30.797 -139.566 59.479 1.00 20.73 ? 178 LEU A CA 1 ATOM 890 C C . LEU A 1 120 ? 31.785 -139.773 58.333 1.00 30.62 ? 178 LEU A C 1 ATOM 891 O O . LEU A 1 120 ? 32.989 -139.586 58.507 1.00 40.40 ? 178 LEU A O 1 ATOM 892 C CB . LEU A 1 120 ? 31.011 -140.636 60.550 1.00 25.62 ? 178 LEU A CB 1 ATOM 893 C CG . LEU A 1 120 ? 30.743 -140.197 61.994 1.00 42.76 ? 178 LEU A CG 1 ATOM 894 C CD1 . LEU A 1 120 ? 29.413 -139.459 62.124 1.00 43.94 ? 178 LEU A CD1 1 ATOM 895 C CD2 . LEU A 1 120 ? 30.776 -141.406 62.921 1.00 34.69 ? 178 LEU A CD2 1 ATOM 896 N N . LEU A 1 121 ? 31.273 -140.149 57.164 1.00 21.17 ? 179 LEU A N 1 ATOM 897 C CA . LEU A 1 121 ? 32.118 -140.402 56.001 1.00 25.30 ? 179 LEU A CA 1 ATOM 898 C C . LEU A 1 121 ? 32.127 -139.216 55.043 1.00 19.59 ? 179 LEU A C 1 ATOM 899 O O . LEU A 1 121 ? 33.131 -138.952 54.385 1.00 23.21 ? 179 LEU A O 1 ATOM 900 C CB . LEU A 1 121 ? 31.648 -141.656 55.258 1.00 26.06 ? 179 LEU A CB 1 ATOM 901 C CG . LEU A 1 121 ? 31.831 -142.996 55.976 1.00 28.35 ? 179 LEU A CG 1 ATOM 902 C CD1 . LEU A 1 121 ? 31.187 -144.116 55.168 1.00 23.58 ? 179 LEU A CD1 1 ATOM 903 C CD2 . LEU A 1 121 ? 33.302 -143.296 56.218 1.00 23.90 ? 179 LEU A CD2 1 ATOM 904 N N . GLU A 1 122 ? 31.013 -138.496 54.978 1.00 20.27 ? 180 GLU A N 1 ATOM 905 C CA . GLU A 1 122 ? 30.826 -137.493 53.935 1.00 34.25 ? 180 GLU A CA 1 ATOM 906 C C . GLU A 1 122 ? 31.551 -136.172 54.212 1.00 34.53 ? 180 GLU A C 1 ATOM 907 O O . GLU A 1 122 ? 31.491 -135.255 53.394 1.00 28.12 ? 180 GLU A O 1 ATOM 908 C CB . GLU A 1 122 ? 29.329 -137.238 53.718 1.00 30.29 ? 180 GLU A CB 1 ATOM 909 C CG . GLU A 1 122 ? 28.563 -136.788 54.951 1.00 47.98 ? 180 GLU A CG 1 ATOM 910 C CD . GLU A 1 122 ? 27.063 -136.728 54.712 1.00 49.29 ? 180 GLU A CD 1 ATOM 911 O OE1 . GLU A 1 122 ? 26.619 -137.113 53.609 1.00 52.75 ? 180 GLU A OE1 1 ATOM 912 O OE2 . GLU A 1 122 ? 26.328 -136.296 55.625 1.00 51.78 ? 180 GLU A OE2 1 ATOM 913 N N . LYS A 1 123 ? 32.242 -136.080 55.346 1.00 37.78 ? 181 LYS A N 1 ATOM 914 C CA . LYS A 1 123 ? 33.073 -134.913 55.650 1.00 35.83 ? 181 LYS A CA 1 ATOM 915 C C . LYS A 1 123 ? 34.405 -135.341 56.265 1.00 30.64 ? 181 LYS A C 1 ATOM 916 O O . LYS A 1 123 ? 35.001 -134.605 57.052 1.00 62.76 ? 181 LYS A O 1 ATOM 917 C CB . LYS A 1 123 ? 32.344 -133.955 56.598 1.00 45.47 ? 181 LYS A CB 1 ATOM 918 C CG . LYS A 1 123 ? 31.055 -133.364 56.032 1.00 52.47 ? 181 LYS A CG 1 ATOM 919 C CD . LYS A 1 123 ? 30.131 -132.859 57.132 1.00 53.47 ? 181 LYS A CD 1 ATOM 920 C CE . LYS A 1 123 ? 29.516 -134.007 57.926 1.00 60.46 ? 181 LYS A CE 1 ATOM 921 N NZ . LYS A 1 123 ? 28.131 -134.330 57.488 1.00 59.23 ? 181 LYS A NZ 1 ATOM 922 N N . ASN A 1 124 ? 34.868 -136.530 55.893 1.00 36.30 ? 182 ASN A N 1 ATOM 923 C CA . ASN A 1 124 ? 36.106 -137.087 56.431 1.00 33.54 ? 182 ASN A CA 1 ATOM 924 C C . ASN A 1 124 ? 37.268 -136.914 55.450 1.00 50.74 ? 182 ASN A C 1 ATOM 925 O O . ASN A 1 124 ? 37.052 -136.731 54.250 1.00 43.63 ? 182 ASN A O 1 ATOM 926 C CB . ASN A 1 124 ? 35.910 -138.566 56.769 1.00 27.81 ? 182 ASN A CB 1 ATOM 927 C CG . ASN A 1 124 ? 37.043 -139.130 57.606 1.00 32.37 ? 182 ASN A CG 1 ATOM 928 O OD1 . ASN A 1 124 ? 38.137 -139.373 57.103 1.00 37.03 ? 182 ASN A OD1 1 ATOM 929 N ND2 . ASN A 1 124 ? 36.781 -139.349 58.889 1.00 53.44 ? 182 ASN A ND2 1 ATOM 930 N N . SER A 1 125 ? 38.497 -136.974 55.964 1.00 35.24 ? 183 SER A N 1 ATOM 931 C CA . SER A 1 125 ? 39.697 -136.734 55.152 1.00 52.05 ? 183 SER A CA 1 ATOM 932 C C . SER A 1 125 ? 40.054 -137.935 54.290 1.00 36.80 ? 183 SER A C 1 ATOM 933 O O . SER A 1 125 ? 40.382 -137.795 53.112 1.00 42.85 ? 183 SER A O 1 ATOM 934 C CB . SER A 1 125 ? 40.896 -136.385 56.045 1.00 45.86 ? 183 SER A CB 1 ATOM 935 O OG . SER A 1 125 ? 41.629 -137.538 56.418 1.00 45.85 ? 183 SER A OG 1 ATOM 936 N N . ASN A 1 126 ? 39.988 -139.116 54.894 1.00 32.00 ? 184 ASN A N 1 ATOM 937 C CA . ASN A 1 126 ? 40.385 -140.351 54.234 1.00 53.99 ? 184 ASN A CA 1 ATOM 938 C C . ASN A 1 126 ? 39.378 -140.824 53.183 1.00 46.38 ? 184 ASN A C 1 ATOM 939 O O . ASN A 1 126 ? 39.559 -141.882 52.584 1.00 43.08 ? 184 ASN A O 1 ATOM 940 C CB . ASN A 1 126 ? 40.582 -141.456 55.279 1.00 48.07 ? 184 ASN A CB 1 ATOM 941 C CG . ASN A 1 126 ? 41.419 -141.003 56.467 1.00 46.53 ? 184 ASN A CG 1 ATOM 942 O OD1 . ASN A 1 126 ? 42.647 -141.087 56.444 1.00 49.02 ? 184 ASN A OD1 1 ATOM 943 N ND2 . ASN A 1 126 ? 40.754 -140.533 57.518 1.00 39.05 ? 184 ASN A ND2 1 ATOM 944 N N . ILE A 1 127 ? 38.324 -140.041 52.963 1.00 33.36 ? 185 ILE A N 1 ATOM 945 C CA . ILE A 1 127 ? 37.239 -140.430 52.065 1.00 31.24 ? 185 ILE A CA 1 ATOM 946 C C . ILE A 1 127 ? 37.028 -139.373 50.983 1.00 24.28 ? 185 ILE A C 1 ATOM 947 O O . ILE A 1 127 ? 36.584 -138.263 51.272 1.00 33.61 ? 185 ILE A O 1 ATOM 948 C CB . ILE A 1 127 ? 35.925 -140.638 52.842 1.00 29.08 ? 185 ILE A CB 1 ATOM 949 C CG1 . ILE A 1 127 ? 36.132 -141.613 54.009 1.00 24.57 ? 185 ILE A CG1 1 ATOM 950 C CG2 . ILE A 1 127 ? 34.831 -141.134 51.912 1.00 35.25 ? 185 ILE A CG2 1 ATOM 951 C CD1 . ILE A 1 127 ? 36.487 -143.027 53.593 1.00 29.82 ? 185 ILE A CD1 1 ATOM 952 N N . LYS A 1 128 ? 37.336 -139.730 49.738 1.00 26.42 ? 186 LYS A N 1 ATOM 953 C CA . LYS A 1 128 ? 37.317 -138.774 48.629 1.00 34.63 ? 186 LYS A CA 1 ATOM 954 C C . LYS A 1 128 ? 36.235 -139.044 47.581 1.00 33.43 ? 186 LYS A C 1 ATOM 955 O O . LYS A 1 128 ? 36.103 -138.290 46.619 1.00 35.66 ? 186 LYS A O 1 ATOM 956 C CB . LYS A 1 128 ? 38.689 -138.756 47.954 1.00 44.06 ? 186 LYS A CB 1 ATOM 957 C CG . LYS A 1 128 ? 39.758 -138.073 48.796 1.00 49.07 ? 186 LYS A CG 1 ATOM 958 C CD . LYS A 1 128 ? 41.157 -138.363 48.284 1.00 62.77 ? 186 LYS A CD 1 ATOM 959 C CE . LYS A 1 128 ? 42.215 -137.900 49.275 1.00 69.99 ? 186 LYS A CE 1 ATOM 960 N NZ . LYS A 1 128 ? 43.471 -138.691 49.157 1.00 74.22 ? 186 LYS A NZ 1 ATOM 961 N N . ALA A 1 129 ? 35.459 -140.106 47.767 1.00 30.41 ? 187 ALA A N 1 ATOM 962 C CA . ALA A 1 129 ? 34.388 -140.433 46.829 1.00 24.65 ? 187 ALA A CA 1 ATOM 963 C C . ALA A 1 129 ? 33.339 -139.324 46.769 1.00 29.82 ? 187 ALA A C 1 ATOM 964 O O . ALA A 1 129 ? 33.073 -138.652 47.767 1.00 28.82 ? 187 ALA A O 1 ATOM 965 C CB . ALA A 1 129 ? 33.740 -141.747 47.211 1.00 29.74 ? 187 ALA A CB 1 ATOM 966 N N . SER A 1 130 ? 32.741 -139.149 45.593 1.00 19.93 ? 188 SER A N 1 ATOM 967 C CA . SER A 1 130 ? 31.804 -138.053 45.351 1.00 28.25 ? 188 SER A CA 1 ATOM 968 C C . SER A 1 130 ? 30.352 -138.393 45.690 1.00 25.43 ? 188 SER A C 1 ATOM 969 O O . SER A 1 130 ? 29.493 -137.509 45.679 1.00 27.45 ? 188 SER A O 1 ATOM 970 C CB . SER A 1 130 ? 31.886 -137.613 43.888 1.00 25.61 ? 188 SER A CB 1 ATOM 971 O OG . SER A 1 130 ? 31.582 -138.688 43.011 1.00 40.89 ? 188 SER A OG 1 ATOM 972 N N . THR A 1 131 ? 30.074 -139.661 45.979 1.00 22.28 ? 189 THR A N 1 ATOM 973 C CA . THR A 1 131 ? 28.720 -140.089 46.330 1.00 26.70 ? 189 THR A CA 1 ATOM 974 C C . THR A 1 131 ? 28.717 -140.988 47.563 1.00 17.23 ? 189 THR A C 1 ATOM 975 O O . THR A 1 131 ? 29.735 -141.586 47.907 1.00 20.43 ? 189 THR A O 1 ATOM 976 C CB . THR A 1 131 ? 28.055 -140.850 45.176 1.00 22.22 ? 189 THR A CB 1 ATOM 977 O OG1 . THR A 1 131 ? 28.736 -142.094 44.977 1.00 21.65 ? 189 THR A OG1 1 ATOM 978 C CG2 . THR A 1 131 ? 28.088 -140.028 43.885 1.00 25.23 ? 189 THR A CG2 1 ATOM 979 N N . ASP A 1 132 ? 27.561 -141.087 48.213 1.00 14.80 ? 190 ASP A N 1 ATOM 980 C CA . ASP A 1 132 ? 27.412 -141.889 49.426 1.00 21.62 ? 190 ASP A CA 1 ATOM 981 C C . ASP A 1 132 ? 27.759 -143.361 49.198 1.00 17.00 ? 190 ASP A C 1 ATOM 982 O O . ASP A 1 132 ? 28.488 -143.971 49.991 1.00 19.10 ? 190 ASP A O 1 ATOM 983 C CB . ASP A 1 132 ? 25.981 -141.773 49.958 1.00 24.64 ? 190 ASP A CB 1 ATOM 984 C CG . ASP A 1 132 ? 25.639 -140.364 50.414 1.00 35.46 ? 190 ASP A CG 1 ATOM 985 O OD1 . ASP A 1 132 ? 26.570 -139.596 50.737 1.00 32.83 ? 190 ASP A OD1 1 ATOM 986 O OD2 . ASP A 1 132 ? 24.438 -140.027 50.456 1.00 36.65 ? 190 ASP A OD2 1 ATOM 987 N N . LEU A 1 133 ? 27.233 -143.933 48.118 1.00 18.77 ? 191 LEU A N 1 ATOM 988 C CA . LEU A 1 133 ? 27.530 -145.321 47.774 1.00 24.47 ? 191 LEU A CA 1 ATOM 989 C C . LEU A 1 133 ? 29.030 -145.491 47.550 1.00 17.75 ? 191 LEU A C 1 ATOM 990 O O . LEU A 1 133 ? 29.645 -146.445 48.040 1.00 21.36 ? 191 LEU A O 1 ATOM 991 C CB . LEU A 1 133 ? 26.748 -145.750 46.529 1.00 18.19 ? 191 LEU A CB 1 ATOM 992 C CG . LEU A 1 133 ? 26.985 -147.179 46.032 1.00 23.10 ? 191 LEU A CG 1 ATOM 993 C CD1 . LEU A 1 133 ? 26.705 -148.199 47.125 1.00 22.88 ? 191 LEU A CD1 1 ATOM 994 C CD2 . LEU A 1 133 ? 26.121 -147.457 44.818 1.00 24.74 ? 191 LEU A CD2 1 ATOM 995 N N . GLY A 1 134 ? 29.615 -144.548 46.818 1.00 19.57 ? 192 GLY A N 1 ATOM 996 C CA . GLY A 1 134 ? 31.049 -144.535 46.592 1.00 15.64 ? 192 GLY A CA 1 ATOM 997 C C . GLY A 1 134 ? 31.825 -144.417 47.892 1.00 14.67 ? 192 GLY A C 1 ATOM 998 O O . GLY A 1 134 ? 32.895 -145.010 48.046 1.00 19.56 ? 192 GLY A O 1 ATOM 999 N N . ARG A 1 135 ? 31.284 -143.650 48.832 1.00 17.78 ? 193 ARG A N 1 ATOM 1000 C CA . ARG A 1 135 ? 31.925 -143.466 50.128 1.00 19.88 ? 193 ARG A CA 1 ATOM 1001 C C . ARG A 1 135 ? 31.886 -144.763 50.932 1.00 22.33 ? 193 ARG A C 1 ATOM 1002 O O . ARG A 1 135 ? 32.879 -145.144 51.558 1.00 19.97 ? 193 ARG A O 1 ATOM 1003 C CB . ARG A 1 135 ? 31.254 -142.331 50.904 1.00 20.95 ? 193 ARG A CB 1 ATOM 1004 C CG . ARG A 1 135 ? 31.606 -140.940 50.387 1.00 20.11 ? 193 ARG A CG 1 ATOM 1005 C CD . ARG A 1 135 ? 30.747 -139.868 51.033 1.00 22.75 ? 193 ARG A CD 1 ATOM 1006 N NE . ARG A 1 135 ? 31.008 -138.549 50.458 1.00 26.81 ? 193 ARG A NE 1 ATOM 1007 C CZ . ARG A 1 135 ? 30.135 -137.821 49.762 1.00 30.10 ? 193 ARG A CZ 1 ATOM 1008 N NH1 . ARG A 1 135 ? 28.897 -138.249 49.539 1.00 30.15 ? 193 ARG A NH1 1 ATOM 1009 N NH2 . ARG A 1 135 ? 30.504 -136.638 49.290 1.00 34.19 ? 193 ARG A NH2 1 ATOM 1010 N N . CYS A 1 136 ? 30.743 -145.443 50.916 1.00 17.72 ? 194 CYS A N 1 ATOM 1011 C CA . CYS A 1 136 ? 30.651 -146.759 51.546 1.00 17.51 ? 194 CYS A CA 1 ATOM 1012 C C . CYS A 1 136 ? 31.645 -147.737 50.910 1.00 15.77 ? 194 CYS A C 1 ATOM 1013 O O . CYS A 1 136 ? 32.410 -148.423 51.608 1.00 21.67 ? 194 CYS A O 1 ATOM 1014 C CB . CYS A 1 136 ? 29.226 -147.310 51.439 1.00 18.48 ? 194 CYS A CB 1 ATOM 1015 S SG . CYS A 1 136 ? 28.977 -148.888 52.295 1.00 27.01 ? 194 CYS A SG 1 ATOM 1016 N N . ALA A 1 137 ? 31.639 -147.796 49.582 1.00 20.34 ? 195 ALA A N 1 ATOM 1017 C CA . ALA A 1 137 ? 32.561 -148.669 48.860 1.00 18.99 ? 195 ALA A CA 1 ATOM 1018 C C . ALA A 1 137 ? 34.014 -148.369 49.212 1.00 19.10 ? 195 ALA A C 1 ATOM 1019 O O . ALA A 1 137 ? 34.812 -149.280 49.444 1.00 19.21 ? 195 ALA A O 1 ATOM 1020 C CB . ALA A 1 137 ? 32.356 -148.529 47.376 1.00 17.34 ? 195 ALA A CB 1 ATOM 1021 N N . GLU A 1 138 ? 34.352 -147.085 49.237 1.00 18.06 ? 196 GLU A N 1 ATOM 1022 C CA . GLU A 1 138 ? 35.701 -146.658 49.571 1.00 20.94 ? 196 GLU A CA 1 ATOM 1023 C C . GLU A 1 138 ? 36.041 -147.072 50.997 1.00 18.43 ? 196 GLU A C 1 ATOM 1024 O O . GLU A 1 138 ? 37.136 -147.564 51.264 1.00 16.87 ? 196 GLU A O 1 ATOM 1025 C CB . GLU A 1 138 ? 35.836 -145.146 49.402 1.00 24.09 ? 196 GLU A CB 1 ATOM 1026 C CG . GLU A 1 138 ? 37.240 -144.618 49.619 1.00 28.28 ? 196 GLU A CG 1 ATOM 1027 C CD . GLU A 1 138 ? 37.339 -143.126 49.367 1.00 36.97 ? 196 GLU A CD 1 ATOM 1028 O OE1 . GLU A 1 138 ? 38.432 -142.554 49.570 1.00 39.54 ? 196 GLU A OE1 1 ATOM 1029 O OE2 . GLU A 1 138 ? 36.321 -142.523 48.964 1.00 37.47 ? 196 GLU A OE2 1 ATOM 1030 N N . PHE A 1 139 ? 35.095 -146.872 51.909 1.00 18.80 ? 197 PHE A N 1 ATOM 1031 C CA . PHE A 1 139 ? 35.262 -147.315 53.287 1.00 17.16 ? 197 PHE A CA 1 ATOM 1032 C C . PHE A 1 139 ? 35.590 -148.800 53.321 1.00 23.24 ? 197 PHE A C 1 ATOM 1033 O O . PHE A 1 139 ? 36.506 -149.226 54.028 1.00 22.32 ? 197 PHE A O 1 ATOM 1034 C CB . PHE A 1 139 ? 33.999 -147.025 54.099 1.00 20.43 ? 197 PHE A CB 1 ATOM 1035 C CG . PHE A 1 139 ? 34.126 -147.344 55.562 1.00 25.26 ? 197 PHE A CG 1 ATOM 1036 C CD1 . PHE A 1 139 ? 34.953 -146.594 56.380 1.00 24.36 ? 197 PHE A CD1 1 ATOM 1037 C CD2 . PHE A 1 139 ? 33.400 -148.383 56.122 1.00 28.61 ? 197 PHE A CD2 1 ATOM 1038 C CE1 . PHE A 1 139 ? 35.064 -146.881 57.726 1.00 29.23 ? 197 PHE A CE1 1 ATOM 1039 C CE2 . PHE A 1 139 ? 33.507 -148.675 57.469 1.00 29.45 ? 197 PHE A CE2 1 ATOM 1040 C CZ . PHE A 1 139 ? 34.340 -147.923 58.272 1.00 25.87 ? 197 PHE A CZ 1 ATOM 1041 N N . ALA A 1 140 ? 34.848 -149.587 52.550 1.00 21.16 ? 198 ALA A N 1 ATOM 1042 C CA . ALA A 1 140 ? 35.136 -151.017 52.453 1.00 18.64 ? 198 ALA A CA 1 ATOM 1043 C C . ALA A 1 140 ? 36.514 -151.308 51.849 1.00 27.76 ? 198 ALA A C 1 ATOM 1044 O O . ALA A 1 140 ? 37.239 -152.174 52.341 1.00 16.51 ? 198 ALA A O 1 ATOM 1045 C CB . ALA A 1 140 ? 34.060 -151.711 51.641 1.00 21.58 ? 198 ALA A CB 1 ATOM 1046 N N . PHE A 1 141 ? 36.875 -150.599 50.783 1.00 19.60 ? 199 PHE A N 1 ATOM 1047 C CA . PHE A 1 141 ? 38.163 -150.837 50.129 1.00 23.34 ? 199 PHE A CA 1 ATOM 1048 C C . PHE A 1 141 ? 39.334 -150.533 51.058 1.00 24.08 ? 199 PHE A C 1 ATOM 1049 O O . PHE A 1 141 ? 40.386 -151.164 50.969 1.00 22.46 ? 199 PHE A O 1 ATOM 1050 C CB . PHE A 1 141 ? 38.298 -150.000 48.854 1.00 18.43 ? 199 PHE A CB 1 ATOM 1051 C CG . PHE A 1 141 ? 39.598 -150.215 48.129 1.00 24.25 ? 199 PHE A CG 1 ATOM 1052 C CD1 . PHE A 1 141 ? 39.834 -151.392 47.437 1.00 18.48 ? 199 PHE A CD1 1 ATOM 1053 C CD2 . PHE A 1 141 ? 40.586 -149.245 48.146 1.00 30.75 ? 199 PHE A CD2 1 ATOM 1054 C CE1 . PHE A 1 141 ? 41.029 -151.596 46.774 1.00 23.52 ? 199 PHE A CE1 1 ATOM 1055 C CE2 . PHE A 1 141 ? 41.784 -149.443 47.484 1.00 23.76 ? 199 PHE A CE2 1 ATOM 1056 C CZ . PHE A 1 141 ? 42.006 -150.620 46.797 1.00 26.13 ? 199 PHE A CZ 1 ATOM 1057 N N . LYS A 1 142 ? 39.144 -149.566 51.949 1.00 23.99 ? 200 LYS A N 1 ATOM 1058 C CA . LYS A 1 142 ? 40.202 -149.152 52.861 1.00 28.89 ? 200 LYS A CA 1 ATOM 1059 C C . LYS A 1 142 ? 40.168 -149.951 54.165 1.00 29.49 ? 200 LYS A C 1 ATOM 1060 O O . LYS A 1 142 ? 40.637 -149.489 55.204 1.00 26.16 ? 200 LYS A O 1 ATOM 1061 C CB . LYS A 1 142 ? 40.088 -147.652 53.131 1.00 21.67 ? 200 LYS A CB 1 ATOM 1062 C CG . LYS A 1 142 ? 40.526 -146.829 51.937 1.00 26.64 ? 200 LYS A CG 1 ATOM 1063 C CD . LYS A 1 142 ? 40.380 -145.337 52.153 1.00 33.02 ? 200 LYS A CD 1 ATOM 1064 C CE . LYS A 1 142 ? 41.075 -144.579 51.029 1.00 31.35 ? 200 LYS A CE 1 ATOM 1065 N NZ . LYS A 1 142 ? 40.548 -143.205 50.837 1.00 32.41 ? 200 LYS A NZ 1 ATOM 1066 N N . THR A 1 143 ? 39.618 -151.160 54.083 1.00 26.83 ? 201 THR A N 1 ATOM 1067 C CA . THR A 1 143 ? 39.589 -152.104 55.195 1.00 23.35 ? 201 THR A CA 1 ATOM 1068 C C . THR A 1 143 ? 40.233 -153.414 54.750 1.00 29.42 ? 201 THR A C 1 ATOM 1069 O O . THR A 1 143 ? 39.784 -154.026 53.780 1.00 30.98 ? 201 THR A O 1 ATOM 1070 C CB . THR A 1 143 ? 38.145 -152.378 55.679 1.00 26.07 ? 201 THR A CB 1 ATOM 1071 O OG1 . THR A 1 143 ? 37.515 -151.146 56.053 1.00 28.83 ? 201 THR A OG1 1 ATOM 1072 C CG2 . THR A 1 143 ? 38.140 -153.328 56.868 1.00 26.90 ? 201 THR A CG2 1 ATOM 1073 N N . VAL A 1 144 ? 41.279 -153.840 55.456 1.00 25.00 ? 202 VAL A N 1 ATOM 1074 C CA . VAL A 1 144 ? 41.987 -155.073 55.114 1.00 24.58 ? 202 VAL A CA 1 ATOM 1075 C C . VAL A 1 144 ? 42.217 -155.954 56.336 1.00 33.59 ? 202 VAL A C 1 ATOM 1076 O O . VAL A 1 144 ? 42.305 -155.470 57.464 1.00 32.36 ? 202 VAL A O 1 ATOM 1077 C CB . VAL A 1 144 ? 43.355 -154.782 54.459 1.00 33.12 ? 202 VAL A CB 1 ATOM 1078 C CG1 . VAL A 1 144 ? 43.174 -153.963 53.192 1.00 30.60 ? 202 VAL A CG1 1 ATOM 1079 C CG2 . VAL A 1 144 ? 44.280 -154.062 55.431 1.00 42.37 ? 202 VAL A CG2 1 ATOM 1080 N N . ALA A 1 145 ? 42.323 -157.254 56.091 1.00 28.50 ? 203 ALA A N 1 ATOM 1081 C CA . ALA A 1 145 ? 42.621 -158.212 57.142 1.00 31.65 ? 203 ALA A CA 1 ATOM 1082 C C . ALA A 1 145 ? 44.088 -158.127 57.549 1.00 29.52 ? 203 ALA A C 1 ATOM 1083 O O . ALA A 1 145 ? 44.965 -157.951 56.703 1.00 32.47 ? 203 ALA A O 1 ATOM 1084 C CB . ALA A 1 145 ? 42.285 -159.619 56.681 1.00 26.13 ? 203 ALA A CB 1 ATOM 1085 N N . MET A 1 146 ? 44.341 -158.242 58.850 1.00 33.23 ? 204 MET A N 1 ATOM 1086 C CA . MET A 1 146 ? 45.699 -158.370 59.369 1.00 33.90 ? 204 MET A CA 1 ATOM 1087 C C . MET A 1 146 ? 46.006 -159.849 59.573 1.00 32.99 ? 204 MET A C 1 ATOM 1088 O O . MET A 1 146 ? 45.122 -160.620 59.948 1.00 36.32 ? 204 MET A O 1 ATOM 1089 C CB . MET A 1 146 ? 45.860 -157.605 60.687 1.00 39.97 ? 204 MET A CB 1 ATOM 1090 C CG . MET A 1 146 ? 45.568 -156.114 60.590 1.00 42.80 ? 204 MET A CG 1 ATOM 1091 S SD . MET A 1 146 ? 46.695 -155.233 59.490 1.00 84.02 ? 204 MET A SD 1 ATOM 1092 C CE . MET A 1 146 ? 47.750 -154.394 60.671 1.00 72.16 ? 204 MET A CE 1 ATOM 1093 N N . ASP A 1 147 ? 47.251 -160.245 59.322 1.00 35.85 ? 205 ASP A N 1 ATOM 1094 C CA . ASP A 1 147 ? 47.650 -161.641 59.481 1.00 51.49 ? 205 ASP A CA 1 ATOM 1095 C C . ASP A 1 147 ? 48.170 -161.911 60.897 1.00 48.42 ? 205 ASP A C 1 ATOM 1096 O O . ASP A 1 147 ? 48.027 -161.071 61.786 1.00 44.09 ? 205 ASP A O 1 ATOM 1097 C CB . ASP A 1 147 ? 48.698 -162.026 58.423 1.00 42.26 ? 205 ASP A CB 1 ATOM 1098 C CG . ASP A 1 147 ? 49.961 -161.182 58.487 1.00 53.74 ? 205 ASP A CG 1 ATOM 1099 O OD1 . ASP A 1 147 ? 50.298 -160.645 59.563 1.00 53.90 ? 205 ASP A OD1 1 ATOM 1100 O OD2 . ASP A 1 147 ? 50.635 -161.073 57.440 1.00 60.92 ? 205 ASP A OD2 1 ATOM 1101 N N . LYS A 1 148 ? 48.759 -163.088 61.102 1.00 51.02 ? 206 LYS A N 1 ATOM 1102 C CA . LYS A 1 148 ? 49.244 -163.494 62.421 1.00 55.28 ? 206 LYS A CA 1 ATOM 1103 C C . LYS A 1 148 ? 50.357 -162.589 62.939 1.00 51.17 ? 206 LYS A C 1 ATOM 1104 O O . LYS A 1 148 ? 50.406 -162.278 64.129 1.00 57.55 ? 206 LYS A O 1 ATOM 1105 C CB . LYS A 1 148 ? 49.737 -164.942 62.387 1.00 52.73 ? 206 LYS A CB 1 ATOM 1106 C CG . LYS A 1 148 ? 48.764 -165.936 63.000 1.00 59.43 ? 206 LYS A CG 1 ATOM 1107 C CD . LYS A 1 148 ? 49.319 -167.351 62.970 1.00 77.51 ? 206 LYS A CD 1 ATOM 1108 C CE . LYS A 1 148 ? 49.124 -167.999 61.609 1.00 89.48 ? 206 LYS A CE 1 ATOM 1109 N NZ . LYS A 1 148 ? 50.359 -168.667 61.114 1.00 84.03 ? 206 LYS A NZ 1 ATOM 1110 N N . ASN A 1 149 ? 51.249 -162.167 62.047 1.00 56.94 ? 207 ASN A N 1 ATOM 1111 C CA . ASN A 1 149 ? 52.331 -161.262 62.424 1.00 53.13 ? 207 ASN A CA 1 ATOM 1112 C C . ASN A 1 149 ? 51.863 -159.809 62.469 1.00 52.83 ? 207 ASN A C 1 ATOM 1113 O O . ASN A 1 149 ? 52.676 -158.888 62.555 1.00 50.48 ? 207 ASN A O 1 ATOM 1114 C CB . ASN A 1 149 ? 53.505 -161.396 61.454 1.00 59.70 ? 207 ASN A CB 1 ATOM 1115 C CG . ASN A 1 149 ? 53.889 -162.842 61.196 1.00 68.66 ? 207 ASN A CG 1 ATOM 1116 O OD1 . ASN A 1 149 ? 54.162 -163.228 60.059 1.00 74.87 ? 207 ASN A OD1 1 ATOM 1117 N ND2 . ASN A 1 149 ? 53.904 -163.651 62.250 1.00 58.74 ? 207 ASN A ND2 1 ATOM 1118 N N . ASN A 1 150 ? 50.549 -159.615 62.401 1.00 54.44 ? 208 ASN A N 1 ATOM 1119 C CA . ASN A 1 150 ? 49.948 -158.288 62.467 1.00 53.13 ? 208 ASN A CA 1 ATOM 1120 C C . ASN A 1 150 ? 50.367 -157.409 61.289 1.00 49.67 ? 208 ASN A C 1 ATOM 1121 O O . ASN A 1 150 ? 50.429 -156.185 61.404 1.00 55.77 ? 208 ASN A O 1 ATOM 1122 C CB . ASN A 1 150 ? 50.308 -157.608 63.789 1.00 60.33 ? 208 ASN A CB 1 ATOM 1123 C CG . ASN A 1 150 ? 49.213 -156.685 64.285 1.00 66.76 ? 208 ASN A CG 1 ATOM 1124 O OD1 . ASN A 1 150 ? 49.116 -155.532 63.864 1.00 69.26 ? 208 ASN A OD1 1 ATOM 1125 N ND2 . ASN A 1 150 ? 48.377 -157.190 65.185 1.00 78.31 ? 208 ASN A ND2 1 ATOM 1126 N N . LYS A 1 151 ? 50.653 -158.048 60.158 1.00 43.62 ? 209 LYS A N 1 ATOM 1127 C CA . LYS A 1 151 ? 50.951 -157.340 58.917 1.00 52.81 ? 209 LYS A CA 1 ATOM 1128 C C . LYS A 1 151 ? 49.687 -157.243 58.073 1.00 48.01 ? 209 LYS A C 1 ATOM 1129 O O . LYS A 1 151 ? 48.853 -158.150 58.087 1.00 42.65 ? 209 LYS A O 1 ATOM 1130 C CB . LYS A 1 151 ? 52.056 -158.051 58.130 1.00 62.65 ? 209 LYS A CB 1 ATOM 1131 C CG . LYS A 1 151 ? 53.367 -158.199 58.880 1.00 68.01 ? 209 LYS A CG 1 ATOM 1132 C CD . LYS A 1 151 ? 54.207 -156.937 58.800 1.00 72.53 ? 209 LYS A CD 1 ATOM 1133 C CE . LYS A 1 151 ? 54.786 -156.573 60.156 1.00 74.78 ? 209 LYS A CE 1 ATOM 1134 N NZ . LYS A 1 151 ? 56.003 -155.727 60.036 1.00 74.77 ? 209 LYS A NZ 1 ATOM 1135 N N . ALA A 1 152 ? 49.548 -156.143 57.342 1.00 48.77 ? 210 ALA A N 1 ATOM 1136 C CA . ALA A 1 152 ? 48.390 -155.937 56.482 1.00 46.85 ? 210 ALA A CA 1 ATOM 1137 C C . ALA A 1 152 ? 48.432 -156.866 55.275 1.00 41.24 ? 210 ALA A C 1 ATOM 1138 O O . ALA A 1 152 ? 49.451 -156.971 54.594 1.00 46.51 ? 210 ALA A O 1 ATOM 1139 C CB . ALA A 1 152 ? 48.319 -154.488 56.028 1.00 36.94 ? 210 ALA A CB 1 ATOM 1140 N N . THR A 1 153 ? 47.315 -157.542 55.026 1.00 38.69 ? 211 THR A N 1 ATOM 1141 C CA . THR A 1 153 ? 47.161 -158.371 53.838 1.00 33.07 ? 211 THR A CA 1 ATOM 1142 C C . THR A 1 153 ? 46.483 -157.554 52.747 1.00 31.96 ? 211 THR A C 1 ATOM 1143 O O . THR A 1 153 ? 46.312 -156.342 52.887 1.00 33.38 ? 211 THR A O 1 ATOM 1144 C CB . THR A 1 153 ? 46.324 -159.631 54.117 1.00 29.56 ? 211 THR A CB 1 ATOM 1145 O OG1 . THR A 1 153 ? 44.953 -159.262 54.318 1.00 30.09 ? 211 THR A OG1 1 ATOM 1146 C CG2 . THR A 1 153 ? 46.845 -160.369 55.348 1.00 34.96 ? 211 THR A CG2 1 ATOM 1147 N N . LYS A 1 154 ? 46.102 -158.225 51.665 1.00 34.53 ? 212 LYS A N 1 ATOM 1148 C CA . LYS A 1 154 ? 45.336 -157.594 50.598 1.00 35.06 ? 212 LYS A CA 1 ATOM 1149 C C . LYS A 1 154 ? 43.974 -158.275 50.483 1.00 25.47 ? 212 LYS A C 1 ATOM 1150 O O . LYS A 1 154 ? 43.306 -158.191 49.453 1.00 30.68 ? 212 LYS A O 1 ATOM 1151 C CB . LYS A 1 154 ? 46.101 -157.661 49.274 1.00 34.68 ? 212 LYS A CB 1 ATOM 1152 C CG . LYS A 1 154 ? 47.597 -157.408 49.428 1.00 42.13 ? 212 LYS A CG 1 ATOM 1153 C CD . LYS A 1 154 ? 48.199 -156.699 48.222 1.00 57.32 ? 212 LYS A CD 1 ATOM 1154 C CE . LYS A 1 154 ? 48.031 -155.189 48.321 1.00 78.20 ? 212 LYS A CE 1 ATOM 1155 N NZ . LYS A 1 154 ? 48.916 -154.461 47.369 1.00 81.32 ? 212 LYS A NZ 1 ATOM 1156 N N . TYR A 1 155 ? 43.572 -158.951 51.556 1.00 23.77 ? 213 TYR A N 1 ATOM 1157 C CA . TYR A 1 155 ? 42.261 -159.579 51.624 1.00 25.30 ? 213 TYR A CA 1 ATOM 1158 C C . TYR A 1 155 ? 41.241 -158.571 52.139 1.00 27.20 ? 213 TYR A C 1 ATOM 1159 O O . TYR A 1 155 ? 41.398 -158.016 53.227 1.00 23.17 ? 213 TYR A O 1 ATOM 1160 C CB . TYR A 1 155 ? 42.303 -160.812 52.524 1.00 24.10 ? 213 TYR A CB 1 ATOM 1161 C CG . TYR A 1 155 ? 40.992 -161.560 52.609 1.00 28.87 ? 213 TYR A CG 1 ATOM 1162 C CD1 . TYR A 1 155 ? 40.046 -161.234 53.571 1.00 30.38 ? 213 TYR A CD1 1 ATOM 1163 C CD2 . TYR A 1 155 ? 40.703 -162.595 51.732 1.00 25.99 ? 213 TYR A CD2 1 ATOM 1164 C CE1 . TYR A 1 155 ? 38.848 -161.913 53.654 1.00 27.19 ? 213 TYR A CE1 1 ATOM 1165 C CE2 . TYR A 1 155 ? 39.505 -163.283 51.807 1.00 24.19 ? 213 TYR A CE2 1 ATOM 1166 C CZ . TYR A 1 155 ? 38.583 -162.937 52.772 1.00 28.31 ? 213 TYR A CZ 1 ATOM 1167 O OH . TYR A 1 155 ? 37.389 -163.615 52.856 1.00 33.75 ? 213 TYR A OH 1 ATOM 1168 N N . ARG A 1 156 ? 40.201 -158.336 51.344 1.00 23.20 ? 214 ARG A N 1 ATOM 1169 C CA . ARG A 1 156 ? 39.182 -157.348 51.674 1.00 25.19 ? 214 ARG A CA 1 ATOM 1170 C C . ARG A 1 156 ? 37.800 -157.981 51.721 1.00 24.94 ? 214 ARG A C 1 ATOM 1171 O O . ARG A 1 156 ? 37.552 -159.012 51.094 1.00 32.65 ? 214 ARG A O 1 ATOM 1172 C CB . ARG A 1 156 ? 39.199 -156.205 50.661 1.00 23.05 ? 214 ARG A CB 1 ATOM 1173 C CG . ARG A 1 156 ? 40.497 -155.420 50.643 1.00 22.79 ? 214 ARG A CG 1 ATOM 1174 C CD . ARG A 1 156 ? 40.407 -154.257 49.678 1.00 27.10 ? 214 ARG A CD 1 ATOM 1175 N NE . ARG A 1 156 ? 41.547 -153.352 49.786 1.00 22.60 ? 214 ARG A NE 1 ATOM 1176 C CZ . ARG A 1 156 ? 42.745 -153.584 49.258 1.00 25.99 ? 214 ARG A CZ 1 ATOM 1177 N NH1 . ARG A 1 156 ? 42.981 -154.705 48.589 1.00 24.27 ? 214 ARG A NH1 1 ATOM 1178 N NH2 . ARG A 1 156 ? 43.714 -152.692 49.407 1.00 28.18 ? 214 ARG A NH2 1 ATOM 1179 N N . TYR A 1 157 ? 36.905 -157.340 52.461 1.00 25.02 ? 215 TYR A N 1 ATOM 1180 C CA . TYR A 1 157 ? 35.577 -157.875 52.711 1.00 24.21 ? 215 TYR A CA 1 ATOM 1181 C C . TYR A 1 157 ? 34.529 -157.135 51.890 1.00 19.98 ? 215 TYR A C 1 ATOM 1182 O O . TYR A 1 157 ? 34.672 -155.942 51.636 1.00 22.17 ? 215 TYR A O 1 ATOM 1183 C CB . TYR A 1 157 ? 35.248 -157.777 54.200 1.00 22.45 ? 215 TYR A CB 1 ATOM 1184 C CG . TYR A 1 157 ? 36.172 -158.603 55.062 1.00 32.41 ? 215 TYR A CG 1 ATOM 1185 C CD1 . TYR A 1 157 ? 37.387 -158.091 55.496 1.00 26.79 ? 215 TYR A CD1 1 ATOM 1186 C CD2 . TYR A 1 157 ? 35.838 -159.900 55.429 1.00 28.34 ? 215 TYR A CD2 1 ATOM 1187 C CE1 . TYR A 1 157 ? 38.240 -158.844 56.277 1.00 29.69 ? 215 TYR A CE1 1 ATOM 1188 C CE2 . TYR A 1 157 ? 36.686 -160.662 56.212 1.00 30.64 ? 215 TYR A CE2 1 ATOM 1189 C CZ . TYR A 1 157 ? 37.886 -160.126 56.633 1.00 27.93 ? 215 TYR A CZ 1 ATOM 1190 O OH . TYR A 1 157 ? 38.736 -160.877 57.412 1.00 33.33 ? 215 TYR A OH 1 ATOM 1191 N N . PRO A 1 158 ? 33.466 -157.838 51.474 1.00 18.75 ? 216 PRO A N 1 ATOM 1192 C CA . PRO A 1 158 ? 32.402 -157.160 50.730 1.00 13.66 ? 216 PRO A CA 1 ATOM 1193 C C . PRO A 1 158 ? 31.574 -156.255 51.631 1.00 21.43 ? 216 PRO A C 1 ATOM 1194 O O . PRO A 1 158 ? 31.657 -156.361 52.855 1.00 15.39 ? 216 PRO A O 1 ATOM 1195 C CB . PRO A 1 158 ? 31.560 -158.316 50.189 1.00 19.04 ? 216 PRO A CB 1 ATOM 1196 C CG . PRO A 1 158 ? 31.765 -159.412 51.169 1.00 18.04 ? 216 PRO A CG 1 ATOM 1197 C CD . PRO A 1 158 ? 33.178 -159.271 51.665 1.00 22.88 ? 216 PRO A CD 1 ATOM 1198 N N . PHE A 1 159 ? 30.785 -155.380 51.022 1.00 16.84 ? 217 PHE A N 1 ATOM 1199 C CA . PHE A 1 159 ? 29.977 -154.428 51.760 1.00 16.31 ? 217 PHE A CA 1 ATOM 1200 C C . PHE A 1 159 ? 28.527 -154.458 51.301 1.00 13.51 ? 217 PHE A C 1 ATOM 1201 O O . PHE A 1 159 ? 28.210 -154.923 50.195 1.00 17.01 ? 217 PHE A O 1 ATOM 1202 C CB . PHE A 1 159 ? 30.537 -153.012 51.594 1.00 16.13 ? 217 PHE A CB 1 ATOM 1203 C CG . PHE A 1 159 ? 30.260 -152.413 50.249 1.00 19.72 ? 217 PHE A CG 1 ATOM 1204 C CD1 . PHE A 1 159 ? 29.098 -151.695 50.024 1.00 18.45 ? 217 PHE A CD1 1 ATOM 1205 C CD2 . PHE A 1 159 ? 31.155 -152.574 49.206 1.00 21.29 ? 217 PHE A CD2 1 ATOM 1206 C CE1 . PHE A 1 159 ? 28.833 -151.150 48.785 1.00 24.75 ? 217 PHE A CE1 1 ATOM 1207 C CE2 . PHE A 1 159 ? 30.897 -152.027 47.966 1.00 24.00 ? 217 PHE A CE2 1 ATOM 1208 C CZ . PHE A 1 159 ? 29.733 -151.314 47.755 1.00 21.71 ? 217 PHE A CZ 1 ATOM 1209 N N . VAL A 1 160 ? 27.659 -153.948 52.168 1.00 12.83 ? 218 VAL A N 1 ATOM 1210 C CA . VAL A 1 160 ? 26.271 -153.681 51.823 1.00 13.20 ? 218 VAL A CA 1 ATOM 1211 C C . VAL A 1 160 ? 25.942 -152.258 52.237 1.00 21.99 ? 218 VAL A C 1 ATOM 1212 O O . VAL A 1 160 ? 26.083 -151.905 53.409 1.00 16.87 ? 218 VAL A O 1 ATOM 1213 C CB . VAL A 1 160 ? 25.294 -154.649 52.514 1.00 13.92 ? 218 VAL A CB 1 ATOM 1214 C CG1 . VAL A 1 160 ? 23.848 -154.256 52.215 1.00 13.86 ? 218 VAL A CG1 1 ATOM 1215 C CG2 . VAL A 1 160 ? 25.558 -156.079 52.066 1.00 16.89 ? 218 VAL A CG2 1 ATOM 1216 N N . TYR A 1 161 ? 25.516 -151.437 51.284 1.00 14.20 ? 219 TYR A N 1 ATOM 1217 C CA . TYR A 1 161 ? 25.045 -150.104 51.626 1.00 16.63 ? 219 TYR A CA 1 ATOM 1218 C C . TYR A 1 161 ? 23.533 -150.113 51.772 1.00 15.12 ? 219 TYR A C 1 ATOM 1219 O O . TYR A 1 161 ? 22.807 -150.520 50.858 1.00 12.55 ? 219 TYR A O 1 ATOM 1220 C CB . TYR A 1 161 ? 25.464 -149.064 50.584 1.00 17.33 ? 219 TYR A CB 1 ATOM 1221 C CG . TYR A 1 161 ? 25.095 -147.656 51.003 1.00 13.17 ? 219 TYR A CG 1 ATOM 1222 C CD1 . TYR A 1 161 ? 25.518 -147.147 52.225 1.00 18.85 ? 219 TYR A CD1 1 ATOM 1223 C CD2 . TYR A 1 161 ? 24.321 -146.840 50.188 1.00 19.71 ? 219 TYR A CD2 1 ATOM 1224 C CE1 . TYR A 1 161 ? 25.184 -145.872 52.625 1.00 22.36 ? 219 TYR A CE1 1 ATOM 1225 C CE2 . TYR A 1 161 ? 23.984 -145.554 50.580 1.00 19.32 ? 219 TYR A CE2 1 ATOM 1226 C CZ . TYR A 1 161 ? 24.419 -145.078 51.802 1.00 25.49 ? 219 TYR A CZ 1 ATOM 1227 O OH . TYR A 1 161 ? 24.096 -143.805 52.216 1.00 29.88 ? 219 TYR A OH 1 ATOM 1228 N N . ASP A 1 162 ? 23.080 -149.682 52.946 1.00 13.40 ? 220 ASP A N 1 ATOM 1229 C CA . ASP A 1 162 ? 21.668 -149.452 53.218 1.00 14.53 ? 220 ASP A CA 1 ATOM 1230 C C . ASP A 1 162 ? 21.400 -147.963 53.017 1.00 20.33 ? 220 ASP A C 1 ATOM 1231 O O . ASP A 1 162 ? 21.767 -147.133 53.859 1.00 23.85 ? 220 ASP A O 1 ATOM 1232 C CB . ASP A 1 162 ? 21.307 -149.901 54.640 1.00 17.95 ? 220 ASP A CB 1 ATOM 1233 C CG . ASP A 1 162 ? 19.813 -149.829 54.925 1.00 21.21 ? 220 ASP A CG 1 ATOM 1234 O OD1 . ASP A 1 162 ? 19.105 -149.049 54.258 1.00 23.23 ? 220 ASP A OD1 1 ATOM 1235 O OD2 . ASP A 1 162 ? 19.347 -150.550 55.834 1.00 32.69 ? 220 ASP A OD2 1 ATOM 1236 N N . SER A 1 163 ? 20.768 -147.643 51.890 1.00 16.79 ? 221 SER A N 1 ATOM 1237 C CA . SER A 1 163 ? 20.584 -146.262 51.458 1.00 23.75 ? 221 SER A CA 1 ATOM 1238 C C . SER A 1 163 ? 19.381 -145.595 52.117 1.00 21.87 ? 221 SER A C 1 ATOM 1239 O O . SER A 1 163 ? 19.263 -144.371 52.099 1.00 29.22 ? 221 SER A O 1 ATOM 1240 C CB . SER A 1 163 ? 20.436 -146.201 49.935 1.00 26.39 ? 221 SER A CB 1 ATOM 1241 O OG . SER A 1 163 ? 19.303 -146.931 49.498 1.00 27.21 ? 221 SER A OG 1 ATOM 1242 N N . LYS A 1 164 ? 18.486 -146.393 52.691 1.00 25.97 ? 222 LYS A N 1 ATOM 1243 C CA . LYS A 1 164 ? 17.347 -145.839 53.416 1.00 29.26 ? 222 LYS A CA 1 ATOM 1244 C C . LYS A 1 164 ? 17.799 -145.372 54.793 1.00 20.15 ? 222 LYS A C 1 ATOM 1245 O O . LYS A 1 164 ? 17.462 -144.273 55.230 1.00 31.30 ? 222 LYS A O 1 ATOM 1246 C CB . LYS A 1 164 ? 16.222 -146.868 53.551 1.00 29.80 ? 222 LYS A CB 1 ATOM 1247 C CG . LYS A 1 164 ? 14.879 -146.260 53.943 1.00 41.06 ? 222 LYS A CG 1 ATOM 1248 C CD . LYS A 1 164 ? 14.129 -147.128 54.945 1.00 66.96 ? 222 LYS A CD 1 ATOM 1249 C CE . LYS A 1 164 ? 13.726 -148.474 54.355 1.00 62.45 ? 222 LYS A CE 1 ATOM 1250 N NZ . LYS A 1 164 ? 12.261 -148.557 54.098 1.00 76.38 ? 222 LYS A NZ 1 ATOM 1251 N N . LYS A 1 165 ? 18.566 -146.219 55.472 1.00 20.67 ? 223 LYS A N 1 ATOM 1252 C CA . LYS A 1 165 ? 19.092 -145.896 56.792 1.00 21.04 ? 223 LYS A CA 1 ATOM 1253 C C . LYS A 1 165 ? 20.403 -145.128 56.694 1.00 17.63 ? 223 LYS A C 1 ATOM 1254 O O . LYS A 1 165 ? 20.897 -144.601 57.691 1.00 25.47 ? 223 LYS A O 1 ATOM 1255 C CB . LYS A 1 165 ? 19.302 -147.169 57.608 1.00 22.79 ? 223 LYS A CB 1 ATOM 1256 C CG . LYS A 1 165 ? 18.017 -147.856 58.028 1.00 30.57 ? 223 LYS A CG 1 ATOM 1257 C CD . LYS A 1 165 ? 18.311 -149.051 58.919 1.00 30.09 ? 223 LYS A CD 1 ATOM 1258 C CE . LYS A 1 165 ? 17.036 -149.703 59.426 1.00 51.44 ? 223 LYS A CE 1 ATOM 1259 N NZ . LYS A 1 165 ? 17.323 -150.835 60.352 1.00 54.12 ? 223 LYS A NZ 1 ATOM 1260 N N . ARG A 1 166 ? 20.957 -145.068 55.486 1.00 21.26 ? 224 ARG A N 1 ATOM 1261 C CA . ARG A 1 166 ? 22.244 -144.424 55.244 1.00 13.67 ? 224 ARG A CA 1 ATOM 1262 C C . ARG A 1 166 ? 23.316 -145.055 56.117 1.00 18.46 ? 224 ARG A C 1 ATOM 1263 O O . ARG A 1 166 ? 24.056 -144.358 56.819 1.00 18.40 ? 224 ARG A O 1 ATOM 1264 C CB . ARG A 1 166 ? 22.154 -142.917 55.494 1.00 18.66 ? 224 ARG A CB 1 ATOM 1265 C CG . ARG A 1 166 ? 21.080 -142.232 54.659 1.00 27.72 ? 224 ARG A CG 1 ATOM 1266 C CD . ARG A 1 166 ? 21.221 -140.721 54.693 1.00 36.84 ? 224 ARG A CD 1 ATOM 1267 N NE . ARG A 1 166 ? 22.256 -140.248 53.771 1.00 33.60 ? 224 ARG A NE 1 ATOM 1268 C CZ . ARG A 1 166 ? 23.186 -139.338 54.060 1.00 36.64 ? 224 ARG A CZ 1 ATOM 1269 N NH1 . ARG A 1 166 ? 23.246 -138.772 55.260 1.00 37.63 ? 224 ARG A NH1 1 ATOM 1270 N NH2 . ARG A 1 166 ? 24.070 -138.989 53.134 1.00 36.45 ? 224 ARG A NH2 1 ATOM 1271 N N . LEU A 1 167 ? 23.391 -146.382 56.056 1.00 18.90 ? 225 LEU A N 1 ATOM 1272 C CA . LEU A 1 167 ? 24.351 -147.141 56.852 1.00 12.66 ? 225 LEU A CA 1 ATOM 1273 C C . LEU A 1 167 ? 25.181 -148.059 55.970 1.00 19.27 ? 225 LEU A C 1 ATOM 1274 O O . LEU A 1 167 ? 24.646 -148.797 55.139 1.00 15.04 ? 225 LEU A O 1 ATOM 1275 C CB . LEU A 1 167 ? 23.643 -147.970 57.930 1.00 18.50 ? 225 LEU A CB 1 ATOM 1276 C CG . LEU A 1 167 ? 22.990 -147.214 59.087 1.00 20.03 ? 225 LEU A CG 1 ATOM 1277 C CD1 . LEU A 1 167 ? 22.201 -148.182 59.957 1.00 22.89 ? 225 LEU A CD1 1 ATOM 1278 C CD2 . LEU A 1 167 ? 24.025 -146.471 59.925 1.00 25.25 ? 225 LEU A CD2 1 ATOM 1279 N N . CYS A 1 168 ? 26.492 -148.005 56.171 1.00 14.70 ? 226 CYS A N 1 ATOM 1280 C CA . CYS A 1 168 ? 27.428 -148.843 55.439 1.00 15.04 ? 226 CYS A CA 1 ATOM 1281 C C . CYS A 1 168 ? 27.813 -150.067 56.263 1.00 19.91 ? 226 CYS A C 1 ATOM 1282 O O . CYS A 1 168 ? 28.332 -149.939 57.372 1.00 22.16 ? 226 CYS A O 1 ATOM 1283 C CB . CYS A 1 168 ? 28.681 -148.051 55.067 1.00 15.98 ? 226 CYS A CB 1 ATOM 1284 S SG . CYS A 1 168 ? 29.876 -149.013 54.120 1.00 37.86 ? 226 CYS A SG 1 ATOM 1285 N N . HIS A 1 169 ? 27.551 -151.248 55.711 1.00 19.22 ? 227 HIS A N 1 ATOM 1286 C CA . HIS A 1 169 ? 27.892 -152.510 56.359 1.00 11.07 ? 227 HIS A CA 1 ATOM 1287 C C . HIS A 1 169 ? 29.087 -153.180 55.692 1.00 21.45 ? 227 HIS A C 1 ATOM 1288 O O . HIS A 1 169 ? 29.132 -153.302 54.468 1.00 23.75 ? 227 HIS A O 1 ATOM 1289 C CB . HIS A 1 169 ? 26.709 -153.478 56.327 1.00 16.58 ? 227 HIS A CB 1 ATOM 1290 C CG . HIS A 1 169 ? 25.464 -152.944 56.961 1.00 15.16 ? 227 HIS A CG 1 ATOM 1291 N ND1 . HIS A 1 169 ? 25.103 -153.242 58.257 1.00 16.71 ? 227 HIS A ND1 1 ATOM 1292 C CD2 . HIS A 1 169 ? 24.483 -152.150 56.470 1.00 18.39 ? 227 HIS A CD2 1 ATOM 1293 C CE1 . HIS A 1 169 ? 23.959 -152.646 58.541 1.00 19.09 ? 227 HIS A CE1 1 ATOM 1294 N NE2 . HIS A 1 169 ? 23.562 -151.977 57.474 1.00 19.53 ? 227 HIS A NE2 1 ATOM 1295 N N . ILE A 1 170 ? 30.044 -153.612 56.509 1.00 16.13 ? 228 ILE A N 1 ATOM 1296 C CA . ILE A 1 170 ? 31.108 -154.509 56.074 1.00 16.58 ? 228 ILE A CA 1 ATOM 1297 C C . ILE A 1 170 ? 30.736 -155.918 56.521 1.00 17.92 ? 228 ILE A C 1 ATOM 1298 O O . ILE A 1 170 ? 30.444 -156.135 57.696 1.00 20.52 ? 228 ILE A O 1 ATOM 1299 C CB . ILE A 1 170 ? 32.481 -154.141 56.676 1.00 16.12 ? 228 ILE A CB 1 ATOM 1300 C CG1 . ILE A 1 170 ? 32.817 -152.661 56.446 1.00 22.37 ? 228 ILE A CG1 1 ATOM 1301 C CG2 . ILE A 1 170 ? 33.571 -155.050 56.111 1.00 18.83 ? 228 ILE A CG2 1 ATOM 1302 C CD1 . ILE A 1 170 ? 33.205 -152.314 55.040 1.00 32.50 ? 228 ILE A CD1 1 ATOM 1303 N N . LEU A 1 171 ? 30.749 -156.871 55.595 1.00 19.76 ? 229 LEU A N 1 ATOM 1304 C CA . LEU A 1 171 ? 30.395 -158.252 55.916 1.00 19.20 ? 229 LEU A CA 1 ATOM 1305 C C . LEU A 1 171 ? 31.624 -159.089 56.236 1.00 21.17 ? 229 LEU A C 1 ATOM 1306 O O . LEU A 1 171 ? 32.529 -159.213 55.416 1.00 26.92 ? 229 LEU A O 1 ATOM 1307 C CB . LEU A 1 171 ? 29.635 -158.896 54.759 1.00 18.36 ? 229 LEU A CB 1 ATOM 1308 C CG . LEU A 1 171 ? 28.344 -158.220 54.296 1.00 19.23 ? 229 LEU A CG 1 ATOM 1309 C CD1 . LEU A 1 171 ? 27.646 -159.106 53.277 1.00 17.20 ? 229 LEU A CD1 1 ATOM 1310 C CD2 . LEU A 1 171 ? 27.423 -157.918 55.463 1.00 20.14 ? 229 LEU A CD2 1 ATOM 1311 N N . TYR A 1 172 ? 31.646 -159.675 57.427 1.00 22.34 ? 230 TYR A N 1 ATOM 1312 C CA . TYR A 1 172 ? 32.731 -160.566 57.817 1.00 23.46 ? 230 TYR A CA 1 ATOM 1313 C C . TYR A 1 172 ? 32.665 -161.861 57.009 1.00 22.97 ? 230 TYR A C 1 ATOM 1314 O O . TYR A 1 172 ? 33.690 -162.470 56.706 1.00 25.48 ? 230 TYR A O 1 ATOM 1315 C CB . TYR A 1 172 ? 32.662 -160.858 59.316 1.00 22.52 ? 230 TYR A CB 1 ATOM 1316 C CG . TYR A 1 172 ? 33.797 -161.703 59.850 1.00 29.68 ? 230 TYR A CG 1 ATOM 1317 C CD1 . TYR A 1 172 ? 35.092 -161.206 59.910 1.00 33.52 ? 230 TYR A CD1 1 ATOM 1318 C CD2 . TYR A 1 172 ? 33.567 -162.991 60.316 1.00 39.30 ? 230 TYR A CD2 1 ATOM 1319 C CE1 . TYR A 1 172 ? 36.131 -161.974 60.406 1.00 40.42 ? 230 TYR A CE1 1 ATOM 1320 C CE2 . TYR A 1 172 ? 34.599 -163.766 60.816 1.00 44.99 ? 230 TYR A CE2 1 ATOM 1321 C CZ . TYR A 1 172 ? 35.878 -163.252 60.860 1.00 45.42 ? 230 TYR A CZ 1 ATOM 1322 O OH . TYR A 1 172 ? 36.908 -164.019 61.355 1.00 55.63 ? 230 TYR A OH 1 ATOM 1323 N N . VAL A 1 173 ? 31.449 -162.268 56.658 1.00 21.13 ? 231 VAL A N 1 ATOM 1324 C CA . VAL A 1 173 ? 31.227 -163.464 55.853 1.00 19.96 ? 231 VAL A CA 1 ATOM 1325 C C . VAL A 1 173 ? 31.158 -163.116 54.370 1.00 26.16 ? 231 VAL A C 1 ATOM 1326 O O . VAL A 1 173 ? 30.300 -162.339 53.947 1.00 22.87 ? 231 VAL A O 1 ATOM 1327 C CB . VAL A 1 173 ? 29.928 -164.177 56.262 1.00 20.85 ? 231 VAL A CB 1 ATOM 1328 C CG1 . VAL A 1 173 ? 29.701 -165.418 55.409 1.00 20.40 ? 231 VAL A CG1 1 ATOM 1329 C CG2 . VAL A 1 173 ? 29.966 -164.542 57.739 1.00 25.57 ? 231 VAL A CG2 1 ATOM 1330 N N . SER A 1 174 ? 32.055 -163.706 53.587 1.00 22.52 ? 232 SER A N 1 ATOM 1331 C CA . SER A 1 174 ? 32.118 -163.456 52.152 1.00 24.76 ? 232 SER A CA 1 ATOM 1332 C C . SER A 1 174 ? 31.368 -164.523 51.359 1.00 28.35 ? 232 SER A C 1 ATOM 1333 O O . SER A 1 174 ? 31.198 -164.392 50.147 1.00 20.17 ? 232 SER A O 1 ATOM 1334 C CB . SER A 1 174 ? 33.573 -163.388 51.687 1.00 21.44 ? 232 SER A CB 1 ATOM 1335 O OG . SER A 1 174 ? 34.238 -162.283 52.273 1.00 29.33 ? 232 SER A OG 1 ATOM 1336 N N . MET A 1 175 ? 30.929 -165.579 52.038 1.00 21.47 ? 233 MET A N 1 ATOM 1337 C CA . MET A 1 175 ? 30.116 -166.604 51.394 1.00 24.92 ? 233 MET A CA 1 ATOM 1338 C C . MET A 1 175 ? 28.781 -165.992 50.990 1.00 19.40 ? 233 MET A C 1 ATOM 1339 O O . MET A 1 175 ? 28.292 -165.077 51.650 1.00 20.57 ? 233 MET A O 1 ATOM 1340 C CB . MET A 1 175 ? 29.894 -167.800 52.324 1.00 22.17 ? 233 MET A CB 1 ATOM 1341 C CG . MET A 1 175 ? 31.157 -168.549 52.701 1.00 22.85 ? 233 MET A CG 1 ATOM 1342 S SD . MET A 1 175 ? 30.791 -170.111 53.525 1.00 27.86 ? 233 MET A SD 1 ATOM 1343 C CE . MET A 1 175 ? 30.111 -169.540 55.082 1.00 23.24 ? 233 MET A CE 1 ATOM 1344 N N . GLN A 1 176 ? 28.196 -166.497 49.908 1.00 19.65 ? 234 GLN A N 1 ATOM 1345 C CA . GLN A 1 176 ? 26.954 -165.940 49.384 1.00 17.43 ? 234 GLN A CA 1 ATOM 1346 C C . GLN A 1 176 ? 25.910 -167.018 49.120 1.00 16.39 ? 234 GLN A C 1 ATOM 1347 O O . GLN A 1 176 ? 24.714 -166.731 49.097 1.00 16.30 ? 234 GLN A O 1 ATOM 1348 C CB . GLN A 1 176 ? 27.240 -165.147 48.109 1.00 16.88 ? 234 GLN A CB 1 ATOM 1349 C CG . GLN A 1 176 ? 28.033 -163.871 48.368 1.00 19.57 ? 234 GLN A CG 1 ATOM 1350 C CD . GLN A 1 176 ? 28.916 -163.483 47.204 1.00 16.88 ? 234 GLN A CD 1 ATOM 1351 O OE1 . GLN A 1 176 ? 28.430 -163.122 46.135 1.00 16.67 ? 234 GLN A OE1 1 ATOM 1352 N NE2 . GLN A 1 176 ? 30.228 -163.559 47.405 1.00 19.49 ? 234 GLN A NE2 1 ATOM 1353 N N . LEU A 1 177 ? 26.358 -168.257 48.940 1.00 18.06 ? 235 LEU A N 1 ATOM 1354 C CA . LEU A 1 177 ? 25.441 -169.369 48.715 1.00 17.38 ? 235 LEU A CA 1 ATOM 1355 C C . LEU A 1 177 ? 25.905 -170.627 49.435 1.00 16.87 ? 235 LEU A C 1 ATOM 1356 O O . LEU A 1 177 ? 27.072 -171.010 49.350 1.00 20.46 ? 235 LEU A O 1 ATOM 1357 C CB . LEU A 1 177 ? 25.297 -169.649 47.215 1.00 17.84 ? 235 LEU A CB 1 ATOM 1358 C CG . LEU A 1 177 ? 24.374 -170.802 46.799 1.00 25.93 ? 235 LEU A CG 1 ATOM 1359 C CD1 . LEU A 1 177 ? 22.959 -170.581 47.283 1.00 29.75 ? 235 LEU A CD1 1 ATOM 1360 C CD2 . LEU A 1 177 ? 24.381 -170.971 45.291 1.00 36.47 ? 235 LEU A CD2 1 ATOM 1361 N N . MET A 1 178 ? 24.984 -171.256 50.156 1.00 17.88 ? 236 MET A N 1 ATOM 1362 C CA . MET A 1 178 ? 25.222 -172.581 50.715 1.00 25.84 ? 236 MET A CA 1 ATOM 1363 C C . MET A 1 178 ? 23.920 -173.373 50.728 1.00 18.29 ? 236 MET A C 1 ATOM 1364 O O . MET A 1 178 ? 22.905 -172.909 51.254 1.00 17.84 ? 236 MET A O 1 ATOM 1365 C CB . MET A 1 178 ? 25.802 -172.496 52.126 1.00 31.01 ? 236 MET A CB 1 ATOM 1366 C CG . MET A 1 178 ? 26.625 -173.722 52.498 1.00 39.71 ? 236 MET A CG 1 ATOM 1367 S SD . MET A 1 178 ? 26.958 -173.869 54.261 1.00 45.26 ? 236 MET A SD 1 ATOM 1368 C CE . MET A 1 178 ? 28.284 -172.684 54.466 1.00 39.07 ? 236 MET A CE 1 ATOM 1369 N N . GLU A 1 179 ? 23.963 -174.570 50.150 1.00 19.92 ? 237 GLU A N 1 ATOM 1370 C CA . GLU A 1 179 ? 22.772 -175.393 49.965 1.00 29.23 ? 237 GLU A CA 1 ATOM 1371 C C . GLU A 1 179 ? 23.104 -176.878 50.087 1.00 24.80 ? 237 GLU A C 1 ATOM 1372 O O . GLU A 1 179 ? 24.263 -177.271 49.960 1.00 27.10 ? 237 GLU A O 1 ATOM 1373 C CB . GLU A 1 179 ? 22.148 -175.111 48.597 1.00 23.93 ? 237 GLU A CB 1 ATOM 1374 C CG . GLU A 1 179 ? 23.079 -175.436 47.430 1.00 36.47 ? 237 GLU A CG 1 ATOM 1375 C CD . GLU A 1 179 ? 22.544 -174.958 46.094 1.00 63.74 ? 237 GLU A CD 1 ATOM 1376 O OE1 . GLU A 1 179 ? 23.320 -174.943 45.114 1.00 48.85 ? 237 GLU A OE1 1 ATOM 1377 O OE2 . GLU A 1 179 ? 21.349 -174.599 46.021 1.00 53.01 ? 237 GLU A OE2 1 ATOM 1378 N N . GLY A 1 180 ? 22.080 -177.694 50.325 1.00 28.08 ? 238 GLY A N 1 ATOM 1379 C CA . GLY A 1 180 ? 22.249 -179.133 50.431 1.00 43.51 ? 238 GLY A CA 1 ATOM 1380 C C . GLY A 1 180 ? 22.296 -179.601 51.872 1.00 43.04 ? 238 GLY A C 1 ATOM 1381 O O . GLY A 1 180 ? 23.071 -179.081 52.674 1.00 35.18 ? 238 GLY A O 1 ATOM 1382 N N . LYS A 1 181 ? 21.471 -180.596 52.194 1.00 40.70 ? 239 LYS A N 1 ATOM 1383 C CA . LYS A 1 181 ? 21.387 -181.137 53.550 1.00 39.74 ? 239 LYS A CA 1 ATOM 1384 C C . LYS A 1 181 ? 22.733 -181.675 54.030 1.00 31.58 ? 239 LYS A C 1 ATOM 1385 O O . LYS A 1 181 ? 22.934 -181.902 55.219 1.00 35.62 ? 239 LYS A O 1 ATOM 1386 C CB . LYS A 1 181 ? 20.335 -182.249 53.616 1.00 48.50 ? 239 LYS A CB 1 ATOM 1387 C CG . LYS A 1 181 ? 20.784 -183.574 53.006 1.00 52.44 ? 239 LYS A CG 1 ATOM 1388 C CD . LYS A 1 181 ? 19.675 -184.612 53.034 0.66 56.42 ? 239 LYS A CD 1 ATOM 1389 C CE . LYS A 1 181 ? 20.095 -185.888 52.323 0.79 54.56 ? 239 LYS A CE 1 ATOM 1390 N NZ . LYS A 1 181 ? 19.187 -186.217 51.191 0.88 53.62 ? 239 LYS A NZ 1 ATOM 1391 N N . LYS A 1 182 ? 23.646 -181.889 53.093 1.00 32.34 ? 240 LYS A N 1 ATOM 1392 C CA . LYS A 1 182 ? 24.983 -182.366 53.409 1.00 34.32 ? 240 LYS A CA 1 ATOM 1393 C C . LYS A 1 182 ? 25.828 -181.278 54.076 1.00 40.31 ? 240 LYS A C 1 ATOM 1394 O O . LYS A 1 182 ? 26.795 -181.577 54.778 1.00 35.51 ? 240 LYS A O 1 ATOM 1395 C CB . LYS A 1 182 ? 25.661 -182.856 52.128 1.00 40.49 ? 240 LYS A CB 1 ATOM 1396 C CG . LYS A 1 182 ? 26.952 -183.624 52.327 1.00 60.35 ? 240 LYS A CG 1 ATOM 1397 C CD . LYS A 1 182 ? 27.291 -184.421 51.072 1.00 61.82 ? 240 LYS A CD 1 ATOM 1398 C CE . LYS A 1 182 ? 28.772 -184.363 50.739 1.00 75.55 ? 240 LYS A CE 1 ATOM 1399 N NZ . LYS A 1 182 ? 29.624 -184.921 51.824 1.00 86.05 ? 240 LYS A NZ 1 ATOM 1400 N N . TYR A 1 183 ? 25.443 -180.021 53.861 1.00 27.99 ? 241 TYR A N 1 ATOM 1401 C CA . TYR A 1 183 ? 26.264 -178.877 54.251 1.00 32.28 ? 241 TYR A CA 1 ATOM 1402 C C . TYR A 1 183 ? 25.580 -177.937 55.240 1.00 25.87 ? 241 TYR A C 1 ATOM 1403 O O . TYR A 1 183 ? 26.249 -177.281 56.035 1.00 25.67 ? 241 TYR A O 1 ATOM 1404 C CB . TYR A 1 183 ? 26.666 -178.084 53.007 1.00 29.97 ? 241 TYR A CB 1 ATOM 1405 C CG . TYR A 1 183 ? 27.483 -178.881 52.018 1.00 41.95 ? 241 TYR A CG 1 ATOM 1406 C CD1 . TYR A 1 183 ? 28.785 -179.256 52.313 1.00 45.06 ? 241 TYR A CD1 1 ATOM 1407 C CD2 . TYR A 1 183 ? 26.955 -179.253 50.789 1.00 40.68 ? 241 TYR A CD2 1 ATOM 1408 C CE1 . TYR A 1 183 ? 29.540 -179.984 51.416 1.00 46.57 ? 241 TYR A CE1 1 ATOM 1409 C CE2 . TYR A 1 183 ? 27.703 -179.981 49.883 1.00 51.67 ? 241 TYR A CE2 1 ATOM 1410 C CZ . TYR A 1 183 ? 28.995 -180.343 50.202 1.00 50.07 ? 241 TYR A CZ 1 ATOM 1411 O OH . TYR A 1 183 ? 29.750 -181.066 49.309 1.00 50.66 ? 241 TYR A OH 1 ATOM 1412 N N . CYS A 1 184 ? 24.254 -177.860 55.184 1.00 23.14 ? 242 CYS A N 1 ATOM 1413 C CA . CYS A 1 184 ? 23.531 -176.885 55.990 1.00 16.62 ? 242 CYS A CA 1 ATOM 1414 C C . CYS A 1 184 ? 22.076 -177.274 56.220 1.00 20.11 ? 242 CYS A C 1 ATOM 1415 O O . CYS A 1 184 ? 21.530 -178.133 55.526 1.00 27.13 ? 242 CYS A O 1 ATOM 1416 C CB . CYS A 1 184 ? 23.598 -175.507 55.325 1.00 25.92 ? 242 CYS A CB 1 ATOM 1417 S SG . CYS A 1 184 ? 22.947 -175.469 53.634 1.00 24.30 ? 242 CYS A SG 1 ATOM 1418 N N . SER A 1 185 ? 21.459 -176.617 57.197 1.00 21.23 ? 243 SER A N 1 ATOM 1419 C CA . SER A 1 185 ? 20.092 -176.916 57.605 1.00 21.13 ? 243 SER A CA 1 ATOM 1420 C C . SER A 1 185 ? 19.109 -175.853 57.138 1.00 25.10 ? 243 SER A C 1 ATOM 1421 O O . SER A 1 185 ? 19.475 -174.693 56.941 1.00 22.40 ? 243 SER A O 1 ATOM 1422 C CB . SER A 1 185 ? 20.014 -177.042 59.129 1.00 22.46 ? 243 SER A CB 1 ATOM 1423 O OG . SER A 1 185 ? 20.455 -175.848 59.754 1.00 24.02 ? 243 SER A OG 1 ATOM 1424 N N . VAL A 1 186 ? 17.859 -176.272 56.975 1.00 24.42 ? 244 VAL A N 1 ATOM 1425 C CA . VAL A 1 186 ? 16.754 -175.383 56.643 1.00 29.21 ? 244 VAL A CA 1 ATOM 1426 C C . VAL A 1 186 ? 15.787 -175.350 57.820 1.00 26.98 ? 244 VAL A C 1 ATOM 1427 O O . VAL A 1 186 ? 15.172 -176.364 58.152 1.00 32.71 ? 244 VAL A O 1 ATOM 1428 C CB . VAL A 1 186 ? 16.018 -175.845 55.367 1.00 26.72 ? 244 VAL A CB 1 ATOM 1429 C CG1 . VAL A 1 186 ? 14.805 -174.973 55.092 1.00 29.82 ? 244 VAL A CG1 1 ATOM 1430 C CG2 . VAL A 1 186 ? 16.959 -175.826 54.181 1.00 24.77 ? 244 VAL A CG2 1 ATOM 1431 N N . LYS A 1 187 ? 15.659 -174.182 58.444 1.00 30.65 ? 245 LYS A N 1 ATOM 1432 C CA . LYS A 1 187 ? 14.831 -174.020 59.636 1.00 29.08 ? 245 LYS A CA 1 ATOM 1433 C C . LYS A 1 187 ? 15.222 -175.019 60.730 1.00 28.43 ? 245 LYS A C 1 ATOM 1434 O O . LYS A 1 187 ? 14.364 -175.544 61.439 1.00 32.66 ? 245 LYS A O 1 ATOM 1435 C CB . LYS A 1 187 ? 13.344 -174.173 59.292 1.00 33.85 ? 245 LYS A CB 1 ATOM 1436 C CG . LYS A 1 187 ? 12.724 -172.984 58.583 1.00 35.64 ? 245 LYS A CG 1 ATOM 1437 C CD . LYS A 1 187 ? 11.210 -173.013 58.759 1.00 57.48 ? 245 LYS A CD 1 ATOM 1438 C CE . LYS A 1 187 ? 10.475 -172.258 57.664 1.00 85.58 ? 245 LYS A CE 1 ATOM 1439 N NZ . LYS A 1 187 ? 10.541 -170.782 57.838 1.00 94.64 ? 245 LYS A NZ 1 ATOM 1440 N N . GLY A 1 188 ? 16.519 -175.283 60.855 1.00 26.32 ? 246 GLY A N 1 ATOM 1441 C CA . GLY A 1 188 ? 17.029 -176.121 61.927 1.00 27.65 ? 246 GLY A CA 1 ATOM 1442 C C . GLY A 1 188 ? 17.046 -177.611 61.625 1.00 35.01 ? 246 GLY A C 1 ATOM 1443 O O . GLY A 1 188 ? 17.412 -178.411 62.487 1.00 36.87 ? 246 GLY A O 1 ATOM 1444 N N . GLU A 1 189 ? 16.652 -177.985 60.409 1.00 33.29 ? 247 GLU A N 1 ATOM 1445 C CA . GLU A 1 189 ? 16.652 -179.388 59.991 1.00 31.10 ? 247 GLU A CA 1 ATOM 1446 C C . GLU A 1 189 ? 17.666 -179.634 58.874 1.00 31.61 ? 247 GLU A C 1 ATOM 1447 O O . GLU A 1 189 ? 17.592 -178.990 57.827 1.00 30.97 ? 247 GLU A O 1 ATOM 1448 C CB . GLU A 1 189 ? 15.258 -179.807 59.522 1.00 37.51 ? 247 GLU A CB 1 ATOM 1449 C CG . GLU A 1 189 ? 14.214 -179.852 60.632 1.00 52.86 ? 247 GLU A CG 1 ATOM 1450 C CD . GLU A 1 189 ? 14.501 -180.924 61.671 1.00 71.31 ? 247 GLU A CD 1 ATOM 1451 O OE1 . GLU A 1 189 ? 15.027 -181.995 61.300 1.00 68.18 ? 247 GLU A OE1 1 ATOM 1452 O OE2 . GLU A 1 189 ? 14.202 -180.691 62.861 1.00 64.86 ? 247 GLU A OE2 1 ATOM 1453 N N . PRO A 1 190 ? 18.617 -180.567 59.079 1.00 32.74 ? 248 PRO A N 1 ATOM 1454 C CA . PRO A 1 190 ? 18.871 -181.390 60.271 1.00 33.47 ? 248 PRO A CA 1 ATOM 1455 C C . PRO A 1 190 ? 19.615 -180.622 61.369 1.00 37.92 ? 248 PRO A C 1 ATOM 1456 O O . PRO A 1 190 ? 20.408 -179.736 61.055 1.00 34.87 ? 248 PRO A O 1 ATOM 1457 C CB . PRO A 1 190 ? 19.727 -182.535 59.726 1.00 39.95 ? 248 PRO A CB 1 ATOM 1458 C CG . PRO A 1 190 ? 20.442 -181.949 58.574 1.00 37.16 ? 248 PRO A CG 1 ATOM 1459 C CD . PRO A 1 190 ? 19.501 -180.948 57.961 1.00 33.26 ? 248 PRO A CD 1 ATOM 1460 N N . PRO A 1 191 ? 19.374 -180.969 62.645 1.00 35.01 ? 249 PRO A N 1 ATOM 1461 C CA . PRO A 1 191 ? 19.915 -180.202 63.776 1.00 31.30 ? 249 PRO A CA 1 ATOM 1462 C C . PRO A 1 191 ? 21.406 -180.415 64.055 1.00 32.40 ? 249 PRO A C 1 ATOM 1463 O O . PRO A 1 191 ? 21.967 -179.689 64.875 1.00 31.38 ? 249 PRO A O 1 ATOM 1464 C CB . PRO A 1 191 ? 19.080 -180.702 64.957 1.00 43.63 ? 249 PRO A CB 1 ATOM 1465 C CG . PRO A 1 191 ? 18.708 -182.094 64.584 1.00 54.85 ? 249 PRO A CG 1 ATOM 1466 C CD . PRO A 1 191 ? 18.526 -182.088 63.093 1.00 46.00 ? 249 PRO A CD 1 ATOM 1467 N N . ASP A 1 192 ? 22.034 -181.379 63.389 1.00 30.74 ? 250 ASP A N 1 ATOM 1468 C CA . ASP A 1 192 ? 23.439 -181.695 63.649 1.00 29.12 ? 250 ASP A CA 1 ATOM 1469 C C . ASP A 1 192 ? 24.400 -180.698 62.997 1.00 31.74 ? 250 ASP A C 1 ATOM 1470 O O . ASP A 1 192 ? 25.588 -180.672 63.319 1.00 27.17 ? 250 ASP A O 1 ATOM 1471 C CB . ASP A 1 192 ? 23.769 -183.108 63.152 1.00 40.79 ? 250 ASP A CB 1 ATOM 1472 C CG . ASP A 1 192 ? 22.939 -184.183 63.838 1.00 71.57 ? 250 ASP A CG 1 ATOM 1473 O OD1 . ASP A 1 192 ? 22.607 -184.018 65.030 1.00 52.69 ? 250 ASP A OD1 1 ATOM 1474 O OD2 . ASP A 1 192 ? 22.624 -185.201 63.184 1.00 39.77 ? 250 ASP A OD2 1 ATOM 1475 N N . LEU A 1 193 ? 23.886 -179.878 62.087 1.00 24.98 ? 251 LEU A N 1 ATOM 1476 C CA . LEU A 1 193 ? 24.739 -179.027 61.263 1.00 26.20 ? 251 LEU A CA 1 ATOM 1477 C C . LEU A 1 193 ? 24.963 -177.636 61.849 1.00 21.48 ? 251 LEU A C 1 ATOM 1478 O O . LEU A 1 193 ? 24.061 -177.029 62.426 1.00 19.64 ? 251 LEU A O 1 ATOM 1479 C CB . LEU A 1 193 ? 24.143 -178.900 59.863 1.00 26.11 ? 251 LEU A CB 1 ATOM 1480 C CG . LEU A 1 193 ? 24.039 -180.217 59.092 1.00 34.44 ? 251 LEU A CG 1 ATOM 1481 C CD1 . LEU A 1 193 ? 23.247 -180.009 57.825 1.00 33.77 ? 251 LEU A CD1 1 ATOM 1482 C CD2 . LEU A 1 193 ? 25.418 -180.781 58.769 1.00 32.69 ? 251 LEU A CD2 1 ATOM 1483 N N . THR A 1 194 ? 26.184 -177.144 61.678 1.00 18.25 ? 252 THR A N 1 ATOM 1484 C CA . THR A 1 194 ? 26.576 -175.825 62.148 1.00 22.43 ? 252 THR A CA 1 ATOM 1485 C C . THR A 1 194 ? 25.896 -174.718 61.352 1.00 28.54 ? 252 THR A C 1 ATOM 1486 O O . THR A 1 194 ? 25.364 -173.765 61.921 1.00 25.96 ? 252 THR A O 1 ATOM 1487 C CB . THR A 1 194 ? 28.103 -175.645 62.048 1.00 23.64 ? 252 THR A CB 1 ATOM 1488 O OG1 . THR A 1 194 ? 28.753 -176.593 62.901 1.00 33.17 ? 252 THR A OG1 1 ATOM 1489 C CG2 . THR A 1 194 ? 28.524 -174.235 62.448 1.00 32.02 ? 252 THR A CG2 1 ATOM 1490 N N . TRP A 1 195 ? 25.924 -174.850 60.030 1.00 23.34 ? 253 TRP A N 1 ATOM 1491 C CA . TRP A 1 195 ? 25.467 -173.784 59.147 1.00 15.84 ? 253 TRP A CA 1 ATOM 1492 C C . TRP A 1 195 ? 24.001 -173.898 58.761 1.00 17.23 ? 253 TRP A C 1 ATOM 1493 O O . TRP A 1 195 ? 23.497 -174.977 58.458 1.00 22.02 ? 253 TRP A O 1 ATOM 1494 C CB . TRP A 1 195 ? 26.318 -173.753 57.876 1.00 21.95 ? 253 TRP A CB 1 ATOM 1495 C CG . TRP A 1 195 ? 27.615 -173.039 58.056 1.00 22.04 ? 253 TRP A CG 1 ATOM 1496 C CD1 . TRP A 1 195 ? 28.853 -173.601 58.180 1.00 24.82 ? 253 TRP A CD1 1 ATOM 1497 C CD2 . TRP A 1 195 ? 27.808 -171.622 58.136 1.00 25.25 ? 253 TRP A CD2 1 ATOM 1498 N NE1 . TRP A 1 195 ? 29.804 -172.621 58.331 1.00 26.76 ? 253 TRP A NE1 1 ATOM 1499 C CE2 . TRP A 1 195 ? 29.188 -171.397 58.308 1.00 25.32 ? 253 TRP A CE2 1 ATOM 1500 C CE3 . TRP A 1 195 ? 26.946 -170.521 58.080 1.00 24.24 ? 253 TRP A CE3 1 ATOM 1501 C CZ2 . TRP A 1 195 ? 29.727 -170.117 58.425 1.00 31.11 ? 253 TRP A CZ2 1 ATOM 1502 C CZ3 . TRP A 1 195 ? 27.484 -169.251 58.195 1.00 22.09 ? 253 TRP A CZ3 1 ATOM 1503 C CH2 . TRP A 1 195 ? 28.861 -169.060 58.365 1.00 28.84 ? 253 TRP A CH2 1 ATOM 1504 N N . TYR A 1 196 ? 23.324 -172.758 58.806 1.00 20.28 ? 254 TYR A N 1 ATOM 1505 C CA . TYR A 1 196 ? 22.029 -172.588 58.167 1.00 17.56 ? 254 TYR A CA 1 ATOM 1506 C C . TYR A 1 196 ? 22.275 -172.406 56.677 1.00 18.38 ? 254 TYR A C 1 ATOM 1507 O O . TYR A 1 196 ? 23.344 -171.944 56.276 1.00 17.25 ? 254 TYR A O 1 ATOM 1508 C CB . TYR A 1 196 ? 21.286 -171.378 58.740 1.00 20.54 ? 254 TYR A CB 1 ATOM 1509 C CG . TYR A 1 196 ? 22.160 -170.147 58.838 1.00 20.61 ? 254 TYR A CG 1 ATOM 1510 C CD1 . TYR A 1 196 ? 22.376 -169.329 57.736 1.00 16.85 ? 254 TYR A CD1 1 ATOM 1511 C CD2 . TYR A 1 196 ? 22.791 -169.819 60.027 1.00 12.89 ? 254 TYR A CD2 1 ATOM 1512 C CE1 . TYR A 1 196 ? 23.187 -168.214 57.824 1.00 20.14 ? 254 TYR A CE1 1 ATOM 1513 C CE2 . TYR A 1 196 ? 23.602 -168.709 60.125 1.00 22.10 ? 254 TYR A CE2 1 ATOM 1514 C CZ . TYR A 1 196 ? 23.796 -167.910 59.022 1.00 20.49 ? 254 TYR A CZ 1 ATOM 1515 O OH . TYR A 1 196 ? 24.606 -166.805 59.124 1.00 17.64 ? 254 TYR A OH 1 ATOM 1516 N N . CYS A 1 197 ? 21.301 -172.776 55.854 1.00 17.63 ? 255 CYS A N 1 ATOM 1517 C CA . CYS A 1 197 ? 21.405 -172.545 54.420 1.00 16.86 ? 255 CYS A CA 1 ATOM 1518 C C . CYS A 1 197 ? 21.086 -171.089 54.105 1.00 23.42 ? 255 CYS A C 1 ATOM 1519 O O . CYS A 1 197 ? 20.358 -170.429 54.844 1.00 18.31 ? 255 CYS A O 1 ATOM 1520 C CB . CYS A 1 197 ? 20.470 -173.481 53.654 1.00 29.34 ? 255 CYS A CB 1 ATOM 1521 S SG . CYS A 1 197 ? 20.933 -175.231 53.800 1.00 32.88 ? 255 CYS A SG 1 ATOM 1522 N N . PHE A 1 198 ? 21.656 -170.582 53.019 1.00 14.86 ? 256 PHE A N 1 ATOM 1523 C CA . PHE A 1 198 ? 21.386 -169.215 52.602 1.00 20.10 ? 256 PHE A CA 1 ATOM 1524 C C . PHE A 1 198 ? 21.689 -169.025 51.130 1.00 22.27 ? 256 PHE A C 1 ATOM 1525 O O . PHE A 1 198 ? 22.470 -169.781 50.550 1.00 18.34 ? 256 PHE A O 1 ATOM 1526 C CB . PHE A 1 198 ? 22.206 -168.225 53.436 1.00 13.94 ? 256 PHE A CB 1 ATOM 1527 C CG . PHE A 1 198 ? 23.684 -168.505 53.439 1.00 15.46 ? 256 PHE A CG 1 ATOM 1528 C CD1 . PHE A 1 198 ? 24.493 -168.032 52.420 1.00 14.26 ? 256 PHE A CD1 1 ATOM 1529 C CD2 . PHE A 1 198 ? 24.266 -169.233 54.465 1.00 16.39 ? 256 PHE A CD2 1 ATOM 1530 C CE1 . PHE A 1 198 ? 25.851 -168.282 52.420 1.00 15.33 ? 256 PHE A CE1 1 ATOM 1531 C CE2 . PHE A 1 198 ? 25.626 -169.487 54.469 1.00 16.46 ? 256 PHE A CE2 1 ATOM 1532 C CZ . PHE A 1 198 ? 26.419 -169.010 53.448 1.00 18.80 ? 256 PHE A CZ 1 ATOM 1533 N N . LYS A 1 199 ? 21.072 -168.017 50.522 1.00 18.31 ? 257 LYS A N 1 ATOM 1534 C CA . LYS A 1 199 ? 21.326 -167.748 49.108 1.00 22.26 ? 257 LYS A CA 1 ATOM 1535 C C . LYS A 1 199 ? 21.070 -166.297 48.719 1.00 14.55 ? 257 LYS A C 1 ATOM 1536 O O . LYS A 1 199 ? 20.323 -165.588 49.397 1.00 20.37 ? 257 LYS A O 1 ATOM 1537 C CB . LYS A 1 199 ? 20.465 -168.662 48.231 1.00 20.27 ? 257 LYS A CB 1 ATOM 1538 C CG . LYS A 1 199 ? 18.973 -168.484 48.439 1.00 20.33 ? 257 LYS A CG 1 ATOM 1539 C CD . LYS A 1 199 ? 18.167 -169.415 47.548 1.00 33.63 ? 257 LYS A CD 1 ATOM 1540 C CE . LYS A 1 199 ? 16.702 -169.429 47.958 1.00 44.51 ? 257 LYS A CE 1 ATOM 1541 N NZ . LYS A 1 199 ? 15.825 -170.028 46.914 1.00 61.70 ? 257 LYS A NZ 1 ATOM 1542 N N . PRO A 1 200 ? 21.684 -165.851 47.609 1.00 19.70 ? 258 PRO A N 1 ATOM 1543 C CA . PRO A 1 200 ? 21.426 -164.490 47.136 1.00 16.49 ? 258 PRO A CA 1 ATOM 1544 C C . PRO A 1 200 ? 20.014 -164.353 46.590 1.00 20.12 ? 258 PRO A C 1 ATOM 1545 O O . PRO A 1 200 ? 19.529 -165.249 45.899 1.00 19.45 ? 258 PRO A O 1 ATOM 1546 C CB . PRO A 1 200 ? 22.463 -164.294 46.023 1.00 14.36 ? 258 PRO A CB 1 ATOM 1547 C CG . PRO A 1 200 ? 23.442 -165.418 46.180 1.00 19.48 ? 258 PRO A CG 1 ATOM 1548 C CD . PRO A 1 200 ? 22.643 -166.544 46.735 1.00 16.87 ? 258 PRO A CD 1 ATOM 1549 N N . ARG A 1 201 ? 19.374 -163.235 46.873 1.00 17.27 ? 259 ARG A N 1 ATOM 1550 C CA . ARG A 1 201 ? 18.037 -162.988 46.377 1.00 17.88 ? 259 ARG A CA 1 ATOM 1551 C C . ARG A 1 201 ? 17.836 -161.532 46.001 1.00 18.81 ? 259 ARG A C 1 ATOM 1552 O O . ARG A 1 201 ? 18.538 -160.653 46.471 1.00 14.92 ? 259 ARG A O 1 ATOM 1553 C CB . ARG A 1 201 ? 16.986 -163.321 47.440 1.00 17.68 ? 259 ARG A CB 1 ATOM 1554 C CG . ARG A 1 201 ? 16.831 -164.782 47.826 1.00 28.50 ? 259 ARG A CG 1 ATOM 1555 C CD . ARG A 1 201 ? 16.110 -165.587 46.762 1.00 24.50 ? 259 ARG A CD 1 ATOM 1556 N NE . ARG A 1 201 ? 17.051 -166.121 45.790 1.00 38.53 ? 259 ARG A NE 1 ATOM 1557 C CZ . ARG A 1 201 ? 16.729 -166.915 44.778 1.00 42.65 ? 259 ARG A CZ 1 ATOM 1558 N NH1 . ARG A 1 201 ? 17.671 -167.342 43.957 1.00 31.03 ? 259 ARG A NH1 1 ATOM 1559 N NH2 . ARG A 1 201 ? 15.473 -167.282 44.587 1.00 38.19 ? 259 ARG A NH2 1 ATOM 1560 N N . LYS A 1 202 ? 16.850 -161.311 45.150 1.00 13.24 ? 260 LYS A N 1 ATOM 1561 C CA . LYS A 1 202 ? 16.388 -160.002 44.773 1.00 18.94 ? 260 LYS A CA 1 ATOM 1562 C C . LYS A 1 202 ? 14.897 -160.210 44.958 1.00 17.85 ? 260 LYS A C 1 ATOM 1563 O O . LYS A 1 202 ? 14.384 -161.286 44.701 1.00 23.81 ? 260 LYS A O 1 ATOM 1564 C CB . LYS A 1 202 ? 16.773 -159.589 43.361 1.00 12.93 ? 260 LYS A CB 1 ATOM 1565 C CG . LYS A 1 202 ? 18.157 -158.983 43.284 1.00 11.55 ? 260 LYS A CG 1 ATOM 1566 C CD . LYS A 1 202 ? 18.364 -158.202 42.008 1.00 15.42 ? 260 LYS A CD 1 ATOM 1567 C CE . LYS A 1 202 ? 19.825 -157.865 41.796 1.00 10.73 ? 260 LYS A CE 1 ATOM 1568 N NZ . LYS A 1 202 ? 20.011 -156.788 40.794 1.00 12.89 ? 260 LYS A NZ 1 ATOM 1569 N N . SER A 1 203 ? 14.208 -159.196 45.436 1.00 18.30 ? 261 SER A N 1 ATOM 1570 C CA . SER A 1 203 ? 12.790 -159.327 45.730 1.00 16.92 ? 261 SER A CA 1 ATOM 1571 C C . SER A 1 203 ? 11.970 -158.278 44.995 1.00 19.79 ? 261 SER A C 1 ATOM 1572 O O . SER A 1 203 ? 12.419 -157.152 44.791 1.00 16.98 ? 261 SER A O 1 ATOM 1573 C CB . SER A 1 203 ? 12.557 -159.219 47.238 1.00 24.13 ? 261 SER A CB 1 ATOM 1574 O OG . SER A 1 203 ? 11.182 -159.059 47.534 1.00 31.09 ? 261 SER A OG 1 ATOM 1575 N N . VAL A 1 204 ? 10.761 -158.663 44.603 1.00 16.46 ? 262 VAL A N 1 ATOM 1576 C CA . VAL A 1 204 ? 9.860 -157.779 43.880 1.00 21.65 ? 262 VAL A CA 1 ATOM 1577 C C . VAL A 1 204 ? 9.523 -156.533 44.697 1.00 22.26 ? 262 VAL A C 1 ATOM 1578 O O . VAL A 1 204 ? 9.310 -155.458 44.134 1.00 27.64 ? 262 VAL A O 1 ATOM 1579 C CB . VAL A 1 204 ? 8.562 -158.528 43.495 1.00 26.37 ? 262 VAL A CB 1 ATOM 1580 C CG1 . VAL A 1 204 ? 7.425 -157.563 43.161 1.00 36.53 ? 262 VAL A CG1 1 ATOM 1581 C CG2 . VAL A 1 204 ? 8.830 -159.458 42.319 1.00 25.08 ? 262 VAL A CG2 1 ATOM 1582 N N . THR A 1 205 ? 9.488 -156.683 46.020 1.00 21.04 ? 263 THR A N 1 ATOM 1583 C CA . THR A 1 205 ? 9.082 -155.600 46.918 1.00 29.55 ? 263 THR A CA 1 ATOM 1584 C C . THR A 1 205 ? 10.129 -155.220 47.972 1.00 25.32 ? 263 THR A C 1 ATOM 1585 O O . THR A 1 205 ? 10.235 -154.053 48.345 1.00 33.54 ? 263 THR A O 1 ATOM 1586 C CB . THR A 1 205 ? 7.787 -155.970 47.669 1.00 38.31 ? 263 THR A CB 1 ATOM 1587 O OG1 . THR A 1 205 ? 7.954 -157.238 48.315 1.00 43.76 ? 263 THR A OG1 1 ATOM 1588 C CG2 . THR A 1 205 ? 6.608 -156.048 46.709 1.00 39.50 ? 263 THR A CG2 1 ATOM 1589 N N . GLU A 1 206 ? 10.893 -156.202 48.446 1.00 25.89 ? 264 GLU A N 1 ATOM 1590 C CA . GLU A 1 206 ? 11.747 -156.023 49.623 1.00 31.31 ? 264 GLU A CA 1 ATOM 1591 C C . GLU A 1 206 ? 13.211 -155.728 49.296 1.00 23.70 ? 264 GLU A C 1 ATOM 1592 O O . GLU A 1 206 ? 13.755 -156.222 48.309 1.00 18.49 ? 264 GLU A O 1 ATOM 1593 C CB . GLU A 1 206 ? 11.684 -157.274 50.505 1.00 32.01 ? 264 GLU A CB 1 ATOM 1594 C CG . GLU A 1 206 ? 10.293 -157.624 51.006 1.00 52.08 ? 264 GLU A CG 1 ATOM 1595 C CD . GLU A 1 206 ? 9.799 -156.660 52.063 1.00 84.48 ? 264 GLU A CD 1 ATOM 1596 O OE1 . GLU A 1 206 ? 8.942 -155.810 51.741 1.00 67.72 ? 264 GLU A OE1 1 ATOM 1597 O OE2 . GLU A 1 206 ? 10.266 -156.753 53.218 1.00 111.60 ? 264 GLU A OE2 1 ATOM 1598 N N . ASN A 1 207 ? 13.835 -154.918 50.147 1.00 17.63 ? 265 ASN A N 1 ATOM 1599 C CA . ASN A 1 207 ? 15.284 -154.717 50.145 1.00 15.73 ? 265 ASN A CA 1 ATOM 1600 C C . ASN A 1 207 ? 15.851 -154.121 48.858 1.00 17.84 ? 265 ASN A C 1 ATOM 1601 O O . ASN A 1 207 ? 16.992 -154.397 48.491 1.00 21.58 ? 265 ASN A O 1 ATOM 1602 C CB . ASN A 1 207 ? 15.987 -156.047 50.442 1.00 18.22 ? 265 ASN A CB 1 ATOM 1603 C CG . ASN A 1 207 ? 15.677 -156.568 51.832 1.00 24.74 ? 265 ASN A CG 1 ATOM 1604 O OD1 . ASN A 1 207 ? 15.669 -155.810 52.802 1.00 28.63 ? 265 ASN A OD1 1 ATOM 1605 N ND2 . ASN A 1 207 ? 15.408 -157.862 51.934 1.00 29.19 ? 265 ASN A ND2 1 ATOM 1606 N N . HIS A 1 208 ? 15.066 -153.288 48.185 1.00 15.85 ? 266 HIS A N 1 ATOM 1607 C CA . HIS A 1 208 ? 15.563 -152.573 47.013 1.00 21.16 ? 266 HIS A CA 1 ATOM 1608 C C . HIS A 1 208 ? 16.621 -151.548 47.408 1.00 22.48 ? 266 HIS A C 1 ATOM 1609 O O . HIS A 1 208 ? 17.453 -151.153 46.592 1.00 26.14 ? 266 HIS A O 1 ATOM 1610 C CB . HIS A 1 208 ? 14.419 -151.874 46.282 1.00 19.41 ? 266 HIS A CB 1 ATOM 1611 C CG . HIS A 1 208 ? 13.423 -152.813 45.680 1.00 22.15 ? 266 HIS A CG 1 ATOM 1612 N ND1 . HIS A 1 208 ? 12.210 -152.390 45.181 1.00 23.66 ? 266 HIS A ND1 1 ATOM 1613 C CD2 . HIS A 1 208 ? 13.459 -154.154 45.494 1.00 21.73 ? 266 HIS A CD2 1 ATOM 1614 C CE1 . HIS A 1 208 ? 11.540 -153.429 44.717 1.00 23.85 ? 266 HIS A CE1 1 ATOM 1615 N NE2 . HIS A 1 208 ? 12.277 -154.512 44.894 1.00 25.94 ? 266 HIS A NE2 1 ATOM 1616 N N . HIS A 1 209 ? 16.579 -151.130 48.669 1.00 19.04 ? 267 HIS A N 1 ATOM 1617 C CA A HIS A 1 209 ? 17.468 -150.098 49.194 0.55 24.09 ? 267 HIS A CA 1 ATOM 1618 C CA B HIS A 1 209 ? 17.484 -150.092 49.151 0.45 24.08 ? 267 HIS A CA 1 ATOM 1619 C C . HIS A 1 209 ? 18.834 -150.651 49.596 1.00 23.92 ? 267 HIS A C 1 ATOM 1620 O O . HIS A 1 209 ? 19.742 -149.891 49.935 1.00 23.13 ? 267 HIS A O 1 ATOM 1621 C CB A HIS A 1 209 ? 16.814 -149.409 50.399 0.55 27.28 ? 267 HIS A CB 1 ATOM 1622 C CB B HIS A 1 209 ? 16.835 -149.321 50.301 0.45 27.21 ? 267 HIS A CB 1 ATOM 1623 C CG A HIS A 1 209 ? 16.377 -150.355 51.475 0.55 29.93 ? 267 HIS A CG 1 ATOM 1624 C CG B HIS A 1 209 ? 15.564 -148.627 49.920 0.45 28.50 ? 267 HIS A CG 1 ATOM 1625 N ND1 A HIS A 1 209 ? 15.277 -151.178 51.342 0.55 22.68 ? 267 HIS A ND1 1 ATOM 1626 N ND1 B HIS A 1 209 ? 15.499 -147.703 48.899 0.45 34.59 ? 267 HIS A ND1 1 ATOM 1627 C CD2 A HIS A 1 209 ? 16.886 -150.611 52.703 0.55 21.06 ? 267 HIS A CD2 1 ATOM 1628 C CD2 B HIS A 1 209 ? 14.311 -148.720 50.423 0.45 29.79 ? 267 HIS A CD2 1 ATOM 1629 C CE1 A HIS A 1 209 ? 15.132 -151.898 52.437 0.55 37.93 ? 267 HIS A CE1 1 ATOM 1630 C CE1 B HIS A 1 209 ? 14.260 -147.259 48.789 0.45 30.13 ? 267 HIS A CE1 1 ATOM 1631 N NE2 A HIS A 1 209 ? 16.097 -151.573 53.282 0.55 25.80 ? 267 HIS A NE2 1 ATOM 1632 N NE2 B HIS A 1 209 ? 13.519 -147.859 49.702 0.45 29.56 ? 267 HIS A NE2 1 ATOM 1633 N N . LEU A 1 210 ? 18.976 -151.975 49.579 1.00 19.08 ? 268 LEU A N 1 ATOM 1634 C CA . LEU A 1 210 ? 20.252 -152.598 49.922 1.00 15.41 ? 268 LEU A CA 1 ATOM 1635 C C . LEU A 1 210 ? 21.090 -152.788 48.667 1.00 18.06 ? 268 LEU A C 1 ATOM 1636 O O . LEU A 1 210 ? 20.615 -153.334 47.669 1.00 16.94 ? 268 LEU A O 1 ATOM 1637 C CB . LEU A 1 210 ? 20.045 -153.944 50.623 1.00 13.77 ? 268 LEU A CB 1 ATOM 1638 C CG . LEU A 1 210 ? 19.334 -153.925 51.978 1.00 17.10 ? 268 LEU A CG 1 ATOM 1639 C CD1 . LEU A 1 210 ? 19.365 -155.317 52.593 1.00 22.34 ? 268 LEU A CD1 1 ATOM 1640 C CD2 . LEU A 1 210 ? 19.951 -152.905 52.929 1.00 21.71 ? 268 LEU A CD2 1 ATOM 1641 N N . ILE A 1 211 ? 22.335 -152.322 48.723 1.00 13.15 ? 269 ILE A N 1 ATOM 1642 C CA . ILE A 1 211 ? 23.257 -152.463 47.601 1.00 16.50 ? 269 ILE A CA 1 ATOM 1643 C C . ILE A 1 211 ? 24.486 -153.263 48.018 1.00 21.22 ? 269 ILE A C 1 ATOM 1644 O O . ILE A 1 211 ? 25.259 -152.833 48.873 1.00 15.79 ? 269 ILE A O 1 ATOM 1645 C CB . ILE A 1 211 ? 23.684 -151.090 47.053 1.00 15.23 ? 269 ILE A CB 1 ATOM 1646 C CG1 . ILE A 1 211 ? 22.440 -150.286 46.659 1.00 19.22 ? 269 ILE A CG1 1 ATOM 1647 C CG2 . ILE A 1 211 ? 24.626 -151.266 45.864 1.00 18.12 ? 269 ILE A CG2 1 ATOM 1648 C CD1 . ILE A 1 211 ? 22.730 -148.929 46.066 1.00 32.74 ? 269 ILE A CD1 1 ATOM 1649 N N . TYR A 1 212 ? 24.649 -154.426 47.392 1.00 16.97 ? 270 TYR A N 1 ATOM 1650 C CA . TYR A 1 212 ? 25.732 -155.353 47.701 1.00 11.20 ? 270 TYR A CA 1 ATOM 1651 C C . TYR A 1 212 ? 26.917 -155.106 46.778 1.00 18.63 ? 270 TYR A C 1 ATOM 1652 O O . TYR A 1 212 ? 26.734 -154.903 45.579 1.00 18.18 ? 270 TYR A O 1 ATOM 1653 C CB . TYR A 1 212 ? 25.242 -156.798 47.555 1.00 14.53 ? 270 TYR A CB 1 ATOM 1654 C CG . TYR A 1 212 ? 26.207 -157.853 48.053 1.00 14.03 ? 270 TYR A CG 1 ATOM 1655 C CD1 . TYR A 1 212 ? 27.301 -158.244 47.290 1.00 18.09 ? 270 TYR A CD1 1 ATOM 1656 C CD2 . TYR A 1 212 ? 26.011 -158.473 49.280 1.00 22.72 ? 270 TYR A CD2 1 ATOM 1657 C CE1 . TYR A 1 212 ? 28.181 -159.214 47.743 1.00 18.56 ? 270 TYR A CE1 1 ATOM 1658 C CE2 . TYR A 1 212 ? 26.882 -159.444 49.740 1.00 18.16 ? 270 TYR A CE2 1 ATOM 1659 C CZ . TYR A 1 212 ? 27.963 -159.810 48.970 1.00 19.32 ? 270 TYR A CZ 1 ATOM 1660 O OH . TYR A 1 212 ? 28.826 -160.776 49.434 1.00 20.42 ? 270 TYR A OH 1 ATOM 1661 N N . GLY A 1 213 ? 28.129 -155.120 47.324 1.00 13.79 ? 271 GLY A N 1 ATOM 1662 C CA . GLY A 1 213 ? 29.306 -154.980 46.484 1.00 15.64 ? 271 GLY A CA 1 ATOM 1663 C C . GLY A 1 213 ? 30.565 -155.573 47.077 1.00 13.35 ? 271 GLY A C 1 ATOM 1664 O O . GLY A 1 213 ? 30.675 -155.716 48.287 1.00 17.60 ? 271 GLY A O 1 ATOM 1665 N N . SER A 1 214 ? 31.519 -155.930 46.223 1.00 18.82 ? 272 SER A N 1 ATOM 1666 C CA . SER A 1 214 ? 32.842 -156.300 46.704 1.00 19.11 ? 272 SER A CA 1 ATOM 1667 C C . SER A 1 214 ? 33.544 -155.022 47.139 1.00 25.44 ? 272 SER A C 1 ATOM 1668 O O . SER A 1 214 ? 33.079 -153.931 46.836 1.00 16.69 ? 272 SER A O 1 ATOM 1669 C CB . SER A 1 214 ? 33.652 -157.021 45.628 1.00 21.08 ? 272 SER A CB 1 ATOM 1670 O OG . SER A 1 214 ? 34.396 -156.103 44.845 1.00 17.17 ? 272 SER A OG 1 ATOM 1671 N N . ALA A 1 215 ? 34.659 -155.145 47.846 1.00 19.32 ? 273 ALA A N 1 ATOM 1672 C CA . ALA A 1 215 ? 35.382 -153.962 48.295 1.00 21.56 ? 273 ALA A CA 1 ATOM 1673 C C . ALA A 1 215 ? 35.932 -153.168 47.109 1.00 25.46 ? 273 ALA A C 1 ATOM 1674 O O . ALA A 1 215 ? 36.143 -151.956 47.197 1.00 25.66 ? 273 ALA A O 1 ATOM 1675 C CB . ALA A 1 215 ? 36.510 -154.360 49.236 1.00 24.38 ? 273 ALA A CB 1 ATOM 1676 N N . TYR A 1 216 ? 36.133 -153.849 45.987 1.00 19.52 ? 274 TYR A N 1 ATOM 1677 C CA . TYR A 1 216 ? 36.885 -153.273 44.881 1.00 20.25 ? 274 TYR A CA 1 ATOM 1678 C C . TYR A 1 216 ? 36.080 -152.317 44.003 1.00 18.56 ? 274 TYR A C 1 ATOM 1679 O O . TYR A 1 216 ? 36.635 -151.714 43.089 1.00 23.83 ? 274 TYR A O 1 ATOM 1680 C CB . TYR A 1 216 ? 37.486 -154.405 44.047 1.00 20.12 ? 274 TYR A CB 1 ATOM 1681 C CG . TYR A 1 216 ? 38.510 -155.163 44.854 1.00 29.28 ? 274 TYR A CG 1 ATOM 1682 C CD1 . TYR A 1 216 ? 39.834 -154.751 44.887 1.00 25.09 ? 274 TYR A CD1 1 ATOM 1683 C CD2 . TYR A 1 216 ? 38.144 -156.255 45.630 1.00 23.73 ? 274 TYR A CD2 1 ATOM 1684 C CE1 . TYR A 1 216 ? 40.771 -155.420 45.644 1.00 26.43 ? 274 TYR A CE1 1 ATOM 1685 C CE2 . TYR A 1 216 ? 39.076 -156.933 46.392 1.00 24.55 ? 274 TYR A CE2 1 ATOM 1686 C CZ . TYR A 1 216 ? 40.388 -156.508 46.398 1.00 26.90 ? 274 TYR A CZ 1 ATOM 1687 O OH . TYR A 1 216 ? 41.328 -157.170 47.152 1.00 31.60 ? 274 TYR A OH 1 ATOM 1688 N N . VAL A 1 217 ? 34.792 -152.138 44.289 1.00 22.07 ? 275 VAL A N 1 ATOM 1689 C CA . VAL A 1 217 ? 34.063 -151.055 43.632 1.00 29.85 ? 275 VAL A CA 1 ATOM 1690 C C . VAL A 1 217 ? 34.525 -149.775 44.328 1.00 23.26 ? 275 VAL A C 1 ATOM 1691 O O . VAL A 1 217 ? 34.340 -148.678 43.805 1.00 19.48 ? 275 VAL A O 1 ATOM 1692 C CB . VAL A 1 217 ? 32.484 -151.223 43.662 1.00 31.76 ? 275 VAL A CB 1 ATOM 1693 C CG1 . VAL A 1 217 ? 32.055 -152.537 44.272 1.00 23.50 ? 275 VAL A CG1 1 ATOM 1694 C CG2 . VAL A 1 217 ? 31.782 -150.074 44.365 1.00 21.81 ? 275 VAL A CG2 1 ATOM 1695 N N . GLY A 1 218 ? 35.179 -149.924 45.483 1.00 24.89 ? 276 GLY A N 1 ATOM 1696 C CA . GLY A 1 218 ? 35.721 -148.785 46.202 1.00 22.48 ? 276 GLY A CA 1 ATOM 1697 C C . GLY A 1 218 ? 37.135 -148.406 45.790 1.00 24.95 ? 276 GLY A C 1 ATOM 1698 O O . GLY A 1 218 ? 37.651 -147.376 46.224 1.00 22.92 ? 276 GLY A O 1 ATOM 1699 N N . GLU A 1 219 ? 37.772 -149.231 44.965 1.00 22.38 ? 277 GLU A N 1 ATOM 1700 C CA . GLU A 1 219 ? 39.142 -148.960 44.532 1.00 25.93 ? 277 GLU A CA 1 ATOM 1701 C C . GLU A 1 219 ? 39.197 -147.669 43.718 1.00 37.35 ? 277 GLU A C 1 ATOM 1702 O O . GLU A 1 219 ? 40.078 -146.833 43.919 1.00 32.66 ? 277 GLU A O 1 ATOM 1703 C CB . GLU A 1 219 ? 39.695 -150.128 43.716 1.00 32.57 ? 277 GLU A CB 1 ATOM 1704 C CG . GLU A 1 219 ? 41.103 -149.893 43.192 1.00 36.46 ? 277 GLU A CG 1 ATOM 1705 C CD . GLU A 1 219 ? 41.782 -151.170 42.733 1.00 44.31 ? 277 GLU A CD 1 ATOM 1706 O OE1 . GLU A 1 219 ? 43.015 -151.149 42.534 1.00 75.48 ? 277 GLU A OE1 1 ATOM 1707 O OE2 . GLU A 1 219 ? 41.086 -152.194 42.569 1.00 52.65 ? 277 GLU A OE2 1 ATOM 1708 N N . ASN A 1 220 ? 38.253 -147.530 42.794 1.00 32.03 ? 278 ASN A N 1 ATOM 1709 C CA . ASN A 1 220 ? 38.007 -146.274 42.095 1.00 28.32 ? 278 ASN A CA 1 ATOM 1710 C C . ASN A 1 220 ? 36.550 -145.881 42.321 1.00 28.40 ? 278 ASN A C 1 ATOM 1711 O O . ASN A 1 220 ? 35.694 -146.133 41.473 1.00 28.15 ? 278 ASN A O 1 ATOM 1712 C CB . ASN A 1 220 ? 38.318 -146.410 40.606 1.00 26.40 ? 278 ASN A CB 1 ATOM 1713 C CG . ASN A 1 220 ? 39.770 -146.761 40.351 1.00 35.95 ? 278 ASN A CG 1 ATOM 1714 O OD1 . ASN A 1 220 ? 40.115 -147.924 40.146 1.00 42.53 ? 278 ASN A OD1 1 ATOM 1715 N ND2 . ASN A 1 220 ? 40.634 -145.754 40.383 1.00 32.26 ? 278 ASN A ND2 1 ATOM 1716 N N . PRO A 1 221 ? 36.264 -145.262 43.478 1.00 27.55 ? 279 PRO A N 1 ATOM 1717 C CA . PRO A 1 221 ? 34.890 -145.164 43.986 1.00 25.83 ? 279 PRO A CA 1 ATOM 1718 C C . PRO A 1 221 ? 33.943 -144.276 43.171 1.00 27.67 ? 279 PRO A C 1 ATOM 1719 O O . PRO A 1 221 ? 32.754 -144.247 43.489 1.00 32.10 ? 279 PRO A O 1 ATOM 1720 C CB . PRO A 1 221 ? 35.086 -144.589 45.394 1.00 24.24 ? 279 PRO A CB 1 ATOM 1721 C CG . PRO A 1 221 ? 36.353 -143.831 45.323 1.00 31.40 ? 279 PRO A CG 1 ATOM 1722 C CD . PRO A 1 221 ? 37.227 -144.576 44.360 1.00 28.87 ? 279 PRO A CD 1 ATOM 1723 N N . ASP A 1 222 ? 34.442 -143.583 42.151 1.00 29.92 ? 280 ASP A N 1 ATOM 1724 C CA . ASP A 1 222 ? 33.585 -142.741 41.314 1.00 29.54 ? 280 ASP A CA 1 ATOM 1725 C C . ASP A 1 222 ? 33.238 -143.409 39.983 1.00 24.34 ? 280 ASP A C 1 ATOM 1726 O O . ASP A 1 222 ? 32.320 -142.977 39.288 1.00 23.12 ? 280 ASP A O 1 ATOM 1727 C CB . ASP A 1 222 ? 34.257 -141.387 41.054 1.00 29.90 ? 280 ASP A CB 1 ATOM 1728 C CG . ASP A 1 222 ? 34.278 -140.496 42.289 1.00 45.14 ? 280 ASP A CG 1 ATOM 1729 O OD1 . ASP A 1 222 ? 33.550 -140.794 43.260 1.00 41.71 ? 280 ASP A OD1 1 ATOM 1730 O OD2 . ASP A 1 222 ? 35.015 -139.488 42.284 1.00 41.56 ? 280 ASP A OD2 1 ATOM 1731 N N . ALA A 1 223 ? 33.957 -144.473 39.645 1.00 21.34 ? 281 ALA A N 1 ATOM 1732 C CA . ALA A 1 223 ? 33.829 -145.106 38.335 1.00 24.85 ? 281 ALA A CA 1 ATOM 1733 C C . ALA A 1 223 ? 32.426 -145.653 38.063 1.00 28.83 ? 281 ALA A C 1 ATOM 1734 O O . ALA A 1 223 ? 31.865 -145.435 36.984 1.00 27.44 ? 281 ALA A O 1 ATOM 1735 C CB . ALA A 1 223 ? 34.851 -146.219 38.205 1.00 24.26 ? 281 ALA A CB 1 ATOM 1736 N N . PHE A 1 224 ? 31.862 -146.354 39.045 1.00 23.72 ? 282 PHE A N 1 ATOM 1737 C CA . PHE A 1 224 ? 30.590 -147.052 38.866 1.00 20.39 ? 282 PHE A CA 1 ATOM 1738 C C . PHE A 1 224 ? 29.493 -146.121 38.356 1.00 20.70 ? 282 PHE A C 1 ATOM 1739 O O . PHE A 1 224 ? 28.545 -146.563 37.709 1.00 20.64 ? 282 PHE A O 1 ATOM 1740 C CB . PHE A 1 224 ? 30.144 -147.704 40.181 1.00 22.93 ? 282 PHE A CB 1 ATOM 1741 C CG . PHE A 1 224 ? 29.497 -146.750 41.145 1.00 18.41 ? 282 PHE A CG 1 ATOM 1742 C CD1 . PHE A 1 224 ? 28.135 -146.500 41.084 1.00 19.41 ? 282 PHE A CD1 1 ATOM 1743 C CD2 . PHE A 1 224 ? 30.248 -146.109 42.116 1.00 21.74 ? 282 PHE A CD2 1 ATOM 1744 C CE1 . PHE A 1 224 ? 27.538 -145.622 41.963 1.00 22.81 ? 282 PHE A CE1 1 ATOM 1745 C CE2 . PHE A 1 224 ? 29.654 -145.232 43.001 1.00 21.95 ? 282 PHE A CE2 1 ATOM 1746 C CZ . PHE A 1 224 ? 28.298 -144.988 42.926 1.00 23.63 ? 282 PHE A CZ 1 ATOM 1747 N N . ILE A 1 225 ? 29.627 -144.835 38.657 1.00 17.50 ? 283 ILE A N 1 ATOM 1748 C CA . ILE A 1 225 ? 28.654 -143.838 38.233 1.00 24.94 ? 283 ILE A CA 1 ATOM 1749 C C . ILE A 1 225 ? 28.489 -143.819 36.714 1.00 29.07 ? 283 ILE A C 1 ATOM 1750 O O . ILE A 1 225 ? 27.387 -143.583 36.215 1.00 30.85 ? 283 ILE A O 1 ATOM 1751 C CB . ILE A 1 225 ? 29.059 -142.429 38.722 1.00 31.73 ? 283 ILE A CB 1 ATOM 1752 C CG1 . ILE A 1 225 ? 29.102 -142.394 40.252 1.00 37.86 ? 283 ILE A CG1 1 ATOM 1753 C CG2 . ILE A 1 225 ? 28.080 -141.375 38.220 1.00 31.82 ? 283 ILE A CG2 1 ATOM 1754 C CD1 . ILE A 1 225 ? 29.742 -141.146 40.819 1.00 37.26 ? 283 ILE A CD1 1 ATOM 1755 N N . SER A 1 226 ? 29.569 -144.086 35.983 1.00 25.11 ? 284 SER A N 1 ATOM 1756 C CA . SER A 1 226 ? 29.542 -143.961 34.525 1.00 31.32 ? 284 SER A CA 1 ATOM 1757 C C . SER A 1 226 ? 29.812 -145.281 33.805 1.00 26.18 ? 284 SER A C 1 ATOM 1758 O O . SER A 1 226 ? 29.529 -145.411 32.614 1.00 40.63 ? 284 SER A O 1 ATOM 1759 C CB . SER A 1 226 ? 30.564 -142.917 34.071 1.00 33.72 ? 284 SER A CB 1 ATOM 1760 O OG . SER A 1 226 ? 31.883 -143.345 34.358 1.00 41.84 ? 284 SER A OG 1 ATOM 1761 N N . LYS A 1 227 ? 30.348 -146.257 34.531 1.00 27.24 ? 285 LYS A N 1 ATOM 1762 C CA . LYS A 1 227 ? 30.791 -147.512 33.930 1.00 26.90 ? 285 LYS A CA 1 ATOM 1763 C C . LYS A 1 227 ? 29.891 -148.704 34.253 1.00 27.30 ? 285 LYS A C 1 ATOM 1764 O O . LYS A 1 227 ? 30.074 -149.782 33.689 1.00 33.94 ? 285 LYS A O 1 ATOM 1765 C CB . LYS A 1 227 ? 32.220 -147.818 34.382 1.00 34.24 ? 285 LYS A CB 1 ATOM 1766 C CG . LYS A 1 227 ? 33.265 -146.885 33.788 1.00 36.15 ? 285 LYS A CG 1 ATOM 1767 C CD . LYS A 1 227 ? 34.562 -146.917 34.584 1.00 58.99 ? 285 LYS A CD 1 ATOM 1768 C CE . LYS A 1 227 ? 35.762 -147.222 33.703 1.00 60.48 ? 285 LYS A CE 1 ATOM 1769 N NZ . LYS A 1 227 ? 35.949 -146.213 32.624 1.00 70.80 ? 285 LYS A NZ 1 ATOM 1770 N N . CYS A 1 228 ? 28.928 -148.515 35.152 1.00 23.42 ? 286 CYS A N 1 ATOM 1771 C CA . CYS A 1 228 ? 28.037 -149.602 35.561 1.00 22.00 ? 286 CYS A CA 1 ATOM 1772 C C . CYS A 1 228 ? 26.581 -149.290 35.217 1.00 22.38 ? 286 CYS A C 1 ATOM 1773 O O . CYS A 1 228 ? 26.172 -148.132 35.253 1.00 22.17 ? 286 CYS A O 1 ATOM 1774 C CB . CYS A 1 228 ? 28.175 -149.870 37.062 1.00 20.55 ? 286 CYS A CB 1 ATOM 1775 S SG . CYS A 1 228 ? 29.817 -150.464 37.555 1.00 33.24 ? 286 CYS A SG 1 ATOM 1776 N N . PRO A 1 229 ? 25.788 -150.327 34.891 1.00 23.71 ? 287 PRO A N 1 ATOM 1777 C CA . PRO A 1 229 ? 24.383 -150.135 34.520 1.00 21.58 ? 287 PRO A CA 1 ATOM 1778 C C . PRO A 1 229 ? 23.477 -150.083 35.750 1.00 23.47 ? 287 PRO A C 1 ATOM 1779 O O . PRO A 1 229 ? 22.682 -150.994 35.985 1.00 21.14 ? 287 PRO A O 1 ATOM 1780 C CB . PRO A 1 229 ? 24.095 -151.364 33.664 1.00 20.18 ? 287 PRO A CB 1 ATOM 1781 C CG . PRO A 1 229 ? 24.923 -152.437 34.302 1.00 21.84 ? 287 PRO A CG 1 ATOM 1782 C CD . PRO A 1 229 ? 26.154 -151.756 34.873 1.00 23.99 ? 287 PRO A CD 1 ATOM 1783 N N . ASN A 1 230 ? 23.600 -149.009 36.521 1.00 17.35 ? 288 ASN A N 1 ATOM 1784 C CA . ASN A 1 230 ? 22.963 -148.921 37.828 1.00 20.11 ? 288 ASN A CA 1 ATOM 1785 C C . ASN A 1 230 ? 21.440 -148.958 37.779 1.00 15.89 ? 288 ASN A C 1 ATOM 1786 O O . ASN A 1 230 ? 20.807 -149.557 38.646 1.00 16.52 ? 288 ASN A O 1 ATOM 1787 C CB . ASN A 1 230 ? 23.422 -147.648 38.528 1.00 17.12 ? 288 ASN A CB 1 ATOM 1788 C CG . ASN A 1 230 ? 24.913 -147.638 38.781 1.00 19.91 ? 288 ASN A CG 1 ATOM 1789 O OD1 . ASN A 1 230 ? 25.452 -148.542 39.422 1.00 18.53 ? 288 ASN A OD1 1 ATOM 1790 N ND2 . ASN A 1 230 ? 25.594 -146.631 38.253 1.00 18.65 ? 288 ASN A ND2 1 ATOM 1791 N N . GLN A 1 231 ? 20.862 -148.325 36.762 1.00 16.64 ? 289 GLN A N 1 ATOM 1792 C CA . GLN A 1 231 ? 19.411 -148.213 36.648 1.00 15.33 ? 289 GLN A CA 1 ATOM 1793 C C . GLN A 1 231 ? 18.845 -149.012 35.480 1.00 13.35 ? 289 GLN A C 1 ATOM 1794 O O . GLN A 1 231 ? 19.541 -149.292 34.504 1.00 13.54 ? 289 GLN A O 1 ATOM 1795 C CB . GLN A 1 231 ? 19.008 -146.745 36.498 1.00 19.26 ? 289 GLN A CB 1 ATOM 1796 C CG . GLN A 1 231 ? 18.696 -146.059 37.817 1.00 26.22 ? 289 GLN A CG 1 ATOM 1797 C CD . GLN A 1 231 ? 19.864 -146.092 38.779 1.00 27.23 ? 289 GLN A CD 1 ATOM 1798 O OE1 . GLN A 1 231 ? 19.826 -146.786 39.797 1.00 29.90 ? 289 GLN A OE1 1 ATOM 1799 N NE2 . GLN A 1 231 ? 20.911 -145.340 38.463 1.00 24.99 ? 289 GLN A NE2 1 ATOM 1800 N N . ALA A 1 232 ? 17.572 -149.375 35.596 1.00 13.63 ? 290 ALA A N 1 ATOM 1801 C CA . ALA A 1 232 ? 16.848 -150.010 34.503 1.00 18.43 ? 290 ALA A CA 1 ATOM 1802 C C . ALA A 1 232 ? 16.683 -149.024 33.351 1.00 17.78 ? 290 ALA A C 1 ATOM 1803 O O . ALA A 1 232 ? 16.687 -147.811 33.561 1.00 17.99 ? 290 ALA A O 1 ATOM 1804 C CB . ALA A 1 232 ? 15.493 -150.504 34.979 1.00 13.79 ? 290 ALA A CB 1 ATOM 1805 N N . LEU A 1 233 ? 16.535 -149.549 32.139 1.00 19.07 ? 291 LEU A N 1 ATOM 1806 C CA . LEU A 1 233 ? 16.393 -148.719 30.947 1.00 17.77 ? 291 LEU A CA 1 ATOM 1807 C C . LEU A 1 233 ? 14.965 -148.782 30.419 1.00 19.98 ? 291 LEU A C 1 ATOM 1808 O O . LEU A 1 233 ? 14.523 -149.818 29.920 1.00 14.65 ? 291 LEU A O 1 ATOM 1809 C CB . LEU A 1 233 ? 17.380 -149.166 29.868 1.00 20.48 ? 291 LEU A CB 1 ATOM 1810 C CG . LEU A 1 233 ? 17.400 -148.336 28.582 1.00 20.08 ? 291 LEU A CG 1 ATOM 1811 C CD1 . LEU A 1 233 ? 17.918 -146.935 28.847 1.00 23.76 ? 291 LEU A CD1 1 ATOM 1812 C CD2 . LEU A 1 233 ? 18.245 -149.025 27.527 1.00 18.59 ? 291 LEU A CD2 1 ATOM 1813 N N . ARG A 1 234 ? 14.252 -147.664 30.526 1.00 15.12 ? 292 ARG A N 1 ATOM 1814 C CA . ARG A 1 234 ? 12.847 -147.600 30.126 1.00 18.16 ? 292 ARG A CA 1 ATOM 1815 C C . ARG A 1 234 ? 12.669 -147.325 28.639 1.00 14.73 ? 292 ARG A C 1 ATOM 1816 O O . ARG A 1 234 ? 13.356 -146.477 28.074 1.00 17.40 ? 292 ARG A O 1 ATOM 1817 C CB . ARG A 1 234 ? 12.117 -146.511 30.912 1.00 24.20 ? 292 ARG A CB 1 ATOM 1818 C CG . ARG A 1 234 ? 10.612 -146.530 30.732 1.00 29.51 ? 292 ARG A CG 1 ATOM 1819 C CD . ARG A 1 234 ? 9.934 -145.576 31.699 1.00 41.44 ? 292 ARG A CD 1 ATOM 1820 N NE . ARG A 1 234 ? 8.481 -145.575 31.545 1.00 70.97 ? 292 ARG A NE 1 ATOM 1821 C CZ . ARG A 1 234 ? 7.623 -145.197 32.489 1.00 85.37 ? 292 ARG A CZ 1 ATOM 1822 N NH1 . ARG A 1 234 ? 8.060 -144.791 33.675 1.00 79.89 ? 292 ARG A NH1 1 ATOM 1823 N NH2 . ARG A 1 234 ? 6.320 -145.233 32.249 1.00 81.27 ? 292 ARG A NH2 1 ATOM 1824 N N . GLY A 1 235 ? 11.733 -148.038 28.019 1.00 13.76 ? 293 GLY A N 1 ATOM 1825 C CA . GLY A 1 235 ? 11.321 -147.745 26.657 1.00 13.97 ? 293 GLY A CA 1 ATOM 1826 C C . GLY A 1 235 ? 12.141 -148.415 25.571 1.00 17.01 ? 293 GLY A C 1 ATOM 1827 O O . GLY A 1 235 ? 11.950 -148.127 24.390 1.00 18.96 ? 293 GLY A O 1 ATOM 1828 N N . TYR A 1 236 ? 13.045 -149.309 25.961 1.00 16.33 ? 294 TYR A N 1 ATOM 1829 C CA . TYR A 1 236 ? 13.896 -150.002 25.000 1.00 14.99 ? 294 TYR A CA 1 ATOM 1830 C C . TYR A 1 236 ? 14.107 -151.467 25.364 1.00 15.83 ? 294 TYR A C 1 ATOM 1831 O O . TYR A 1 236 ? 14.093 -151.841 26.537 1.00 15.36 ? 294 TYR A O 1 ATOM 1832 C CB . TYR A 1 236 ? 15.260 -149.316 24.895 1.00 17.25 ? 294 TYR A CB 1 ATOM 1833 C CG . TYR A 1 236 ? 15.230 -147.923 24.313 1.00 18.35 ? 294 TYR A CG 1 ATOM 1834 C CD1 . TYR A 1 236 ? 15.277 -147.723 22.940 1.00 20.55 ? 294 TYR A CD1 1 ATOM 1835 C CD2 . TYR A 1 236 ? 15.182 -146.806 25.136 1.00 21.35 ? 294 TYR A CD2 1 ATOM 1836 C CE1 . TYR A 1 236 ? 15.262 -146.451 22.402 1.00 19.30 ? 294 TYR A CE1 1 ATOM 1837 C CE2 . TYR A 1 236 ? 15.167 -145.528 24.608 1.00 24.43 ? 294 TYR A CE2 1 ATOM 1838 C CZ . TYR A 1 236 ? 15.207 -145.357 23.240 1.00 29.47 ? 294 TYR A CZ 1 ATOM 1839 O OH . TYR A 1 236 ? 15.192 -144.087 22.709 1.00 33.03 ? 294 TYR A OH 1 ATOM 1840 N N . ARG A 1 237 ? 14.307 -152.279 24.330 1.00 16.20 ? 295 ARG A N 1 ATOM 1841 C CA . ARG A 1 237 ? 14.734 -153.662 24.466 1.00 15.53 ? 295 ARG A CA 1 ATOM 1842 C C . ARG A 1 237 ? 16.203 -153.768 24.099 1.00 17.03 ? 295 ARG A C 1 ATOM 1843 O O . ARG A 1 237 ? 16.618 -153.242 23.062 1.00 15.71 ? 295 ARG A O 1 ATOM 1844 C CB . ARG A 1 237 ? 13.931 -154.587 23.552 1.00 14.94 ? 295 ARG A CB 1 ATOM 1845 C CG . ARG A 1 237 ? 12.427 -154.502 23.665 1.00 17.73 ? 295 ARG A CG 1 ATOM 1846 C CD . ARG A 1 237 ? 11.796 -155.453 22.653 1.00 13.56 ? 295 ARG A CD 1 ATOM 1847 N NE . ARG A 1 237 ? 10.337 -155.452 22.692 1.00 21.90 ? 295 ARG A NE 1 ATOM 1848 C CZ . ARG A 1 237 ? 9.574 -156.398 22.151 1.00 25.07 ? 295 ARG A CZ 1 ATOM 1849 N NH1 . ARG A 1 237 ? 8.254 -156.313 22.234 1.00 21.85 ? 295 ARG A NH1 1 ATOM 1850 N NH2 . ARG A 1 237 ? 10.125 -157.436 21.534 1.00 22.44 ? 295 ARG A NH2 1 ATOM 1851 N N . PHE A 1 238 ? 16.981 -154.446 24.938 1.00 16.74 ? 296 PHE A N 1 ATOM 1852 C CA . PHE A 1 238 ? 18.359 -154.783 24.604 1.00 15.75 ? 296 PHE A CA 1 ATOM 1853 C C . PHE A 1 238 ? 18.394 -155.553 23.293 1.00 18.10 ? 296 PHE A C 1 ATOM 1854 O O . PHE A 1 238 ? 17.530 -156.396 23.043 1.00 15.20 ? 296 PHE A O 1 ATOM 1855 C CB . PHE A 1 238 ? 19.004 -155.632 25.705 1.00 15.97 ? 296 PHE A CB 1 ATOM 1856 C CG . PHE A 1 238 ? 19.410 -154.864 26.934 1.00 14.31 ? 296 PHE A CG 1 ATOM 1857 C CD1 . PHE A 1 238 ? 19.851 -153.552 26.854 1.00 13.66 ? 296 PHE A CD1 1 ATOM 1858 C CD2 . PHE A 1 238 ? 19.368 -155.476 28.178 1.00 16.19 ? 296 PHE A CD2 1 ATOM 1859 C CE1 . PHE A 1 238 ? 20.230 -152.864 27.992 1.00 16.05 ? 296 PHE A CE1 1 ATOM 1860 C CE2 . PHE A 1 238 ? 19.747 -154.794 29.319 1.00 17.15 ? 296 PHE A CE2 1 ATOM 1861 C CZ . PHE A 1 238 ? 20.177 -153.486 29.227 1.00 16.58 ? 296 PHE A CZ 1 ATOM 1862 N N . GLY A 1 239 ? 19.389 -155.265 22.460 1.00 19.22 ? 297 GLY A N 1 ATOM 1863 C CA . GLY A 1 239 ? 19.555 -155.992 21.218 1.00 19.76 ? 297 GLY A CA 1 ATOM 1864 C C . GLY A 1 239 ? 20.994 -156.127 20.761 1.00 21.46 ? 297 GLY A C 1 ATOM 1865 O O . GLY A 1 239 ? 21.894 -155.422 21.245 1.00 22.65 ? 297 GLY A O 1 ATOM 1866 N N . VAL A 1 240 ? 21.195 -157.040 19.813 1.00 19.12 ? 298 VAL A N 1 ATOM 1867 C CA . VAL A 1 240 ? 22.493 -157.243 19.176 1.00 21.40 ? 298 VAL A CA 1 ATOM 1868 C C . VAL A 1 240 ? 22.416 -156.832 17.708 1.00 23.09 ? 298 VAL A C 1 ATOM 1869 O O . VAL A 1 240 ? 21.439 -157.129 17.018 1.00 23.47 ? 298 VAL A O 1 ATOM 1870 C CB . VAL A 1 240 ? 22.967 -158.709 19.273 1.00 22.16 ? 298 VAL A CB 1 ATOM 1871 C CG1 . VAL A 1 240 ? 23.079 -159.136 20.729 1.00 29.06 ? 298 VAL A CG1 1 ATOM 1872 C CG2 . VAL A 1 240 ? 22.028 -159.637 18.516 1.00 37.27 ? 298 VAL A CG2 1 ATOM 1873 N N . TRP A 1 241 ? 23.452 -156.149 17.235 1.00 20.81 ? 299 TRP A N 1 ATOM 1874 C CA . TRP A 1 241 ? 23.470 -155.643 15.871 1.00 23.94 ? 299 TRP A CA 1 ATOM 1875 C C . TRP A 1 241 ? 23.983 -156.706 14.914 1.00 30.07 ? 299 TRP A C 1 ATOM 1876 O O . TRP A 1 241 ? 25.137 -157.125 15.000 1.00 26.69 ? 299 TRP A O 1 ATOM 1877 C CB . TRP A 1 241 ? 24.335 -154.390 15.772 1.00 21.22 ? 299 TRP A CB 1 ATOM 1878 C CG . TRP A 1 241 ? 24.302 -153.745 14.419 1.00 28.81 ? 299 TRP A CG 1 ATOM 1879 C CD1 . TRP A 1 241 ? 25.215 -153.896 13.413 1.00 30.03 ? 299 TRP A CD1 1 ATOM 1880 C CD2 . TRP A 1 241 ? 23.303 -152.846 13.922 1.00 23.91 ? 299 TRP A CD2 1 ATOM 1881 N NE1 . TRP A 1 241 ? 24.847 -153.144 12.324 1.00 26.02 ? 299 TRP A NE1 1 ATOM 1882 C CE2 . TRP A 1 241 ? 23.677 -152.491 12.609 1.00 25.67 ? 299 TRP A CE2 1 ATOM 1883 C CE3 . TRP A 1 241 ? 22.131 -152.306 14.459 1.00 23.09 ? 299 TRP A CE3 1 ATOM 1884 C CZ2 . TRP A 1 241 ? 22.921 -151.620 11.828 1.00 26.98 ? 299 TRP A CZ2 1 ATOM 1885 C CZ3 . TRP A 1 241 ? 21.380 -151.441 13.680 1.00 25.15 ? 299 TRP A CZ3 1 ATOM 1886 C CH2 . TRP A 1 241 ? 21.779 -151.107 12.379 1.00 31.51 ? 299 TRP A CH2 1 ATOM 1887 N N . LYS A 1 242 ? 23.118 -157.139 14.005 1.00 25.42 ? 300 LYS A N 1 ATOM 1888 C CA . LYS A 1 242 ? 23.484 -158.152 13.026 1.00 32.80 ? 300 LYS A CA 1 ATOM 1889 C C . LYS A 1 242 ? 22.831 -157.867 11.680 1.00 30.80 ? 300 LYS A C 1 ATOM 1890 O O . LYS A 1 242 ? 21.704 -157.364 11.615 1.00 28.25 ? 300 LYS A O 1 ATOM 1891 C CB . LYS A 1 242 ? 23.102 -159.547 13.531 1.00 34.26 ? 300 LYS A CB 1 ATOM 1892 C CG . LYS A 1 242 ? 24.263 -160.281 14.196 1.00 49.91 ? 300 LYS A CG 1 ATOM 1893 C CD . LYS A 1 242 ? 23.837 -161.135 15.384 1.00 57.33 ? 300 LYS A CD 1 ATOM 1894 C CE . LYS A 1 242 ? 23.144 -162.418 14.957 1.00 72.03 ? 300 LYS A CE 1 ATOM 1895 N NZ . LYS A 1 242 ? 23.189 -163.445 16.036 1.00 66.75 ? 300 LYS A NZ 1 ATOM 1896 N N . LYS A 1 243 ? 23.572 -158.178 10.618 1.00 41.33 ? 301 LYS A N 1 ATOM 1897 C CA . LYS A 1 243 ? 23.129 -157.980 9.241 1.00 32.92 ? 301 LYS A CA 1 ATOM 1898 C C . LYS A 1 243 ? 22.407 -156.651 9.052 1.00 28.32 ? 301 LYS A C 1 ATOM 1899 O O . LYS A 1 243 ? 21.296 -156.596 8.527 1.00 31.18 ? 301 LYS A O 1 ATOM 1900 C CB . LYS A 1 243 ? 22.232 -159.137 8.808 1.00 37.22 ? 301 LYS A CB 1 ATOM 1901 C CG . LYS A 1 243 ? 22.974 -160.463 8.698 1.00 49.57 ? 301 LYS A CG 1 ATOM 1902 C CD . LYS A 1 243 ? 22.018 -161.626 8.516 1.00 72.45 ? 301 LYS A CD 1 ATOM 1903 C CE . LYS A 1 243 ? 21.329 -161.992 9.822 1.00 91.48 ? 301 LYS A CE 1 ATOM 1904 N NZ . LYS A 1 243 ? 20.093 -162.787 9.599 1.00 97.88 ? 301 LYS A NZ 1 ATOM 1905 N N . GLY A 1 244 ? 23.049 -155.582 9.507 1.00 24.53 ? 302 GLY A N 1 ATOM 1906 C CA . GLY A 1 244 ? 22.558 -154.239 9.282 1.00 26.99 ? 302 GLY A CA 1 ATOM 1907 C C . GLY A 1 244 ? 21.328 -153.855 10.077 1.00 27.25 ? 302 GLY A C 1 ATOM 1908 O O . GLY A 1 244 ? 20.690 -152.849 9.762 1.00 27.48 ? 302 GLY A O 1 ATOM 1909 N N . ARG A 1 245 ? 20.971 -154.629 11.096 1.00 23.03 ? 303 ARG A N 1 ATOM 1910 C CA . ARG A 1 245 ? 19.876 -154.196 11.953 1.00 28.59 ? 303 ARG A CA 1 ATOM 1911 C C . ARG A 1 245 ? 19.998 -154.698 13.382 1.00 19.48 ? 303 ARG A C 1 ATOM 1912 O O . ARG A 1 245 ? 20.798 -155.585 13.690 1.00 20.64 ? 303 ARG A O 1 ATOM 1913 C CB . ARG A 1 245 ? 18.535 -154.633 11.358 1.00 24.94 ? 303 ARG A CB 1 ATOM 1914 C CG . ARG A 1 245 ? 18.280 -156.122 11.392 1.00 31.40 ? 303 ARG A CG 1 ATOM 1915 C CD . ARG A 1 245 ? 16.979 -156.465 10.687 1.00 34.36 ? 303 ARG A CD 1 ATOM 1916 N NE . ARG A 1 245 ? 16.651 -157.883 10.820 1.00 29.79 ? 303 ARG A NE 1 ATOM 1917 C CZ . ARG A 1 245 ? 15.812 -158.391 11.720 1.00 31.13 ? 303 ARG A CZ 1 ATOM 1918 N NH1 . ARG A 1 245 ? 15.186 -157.607 12.590 1.00 30.43 ? 303 ARG A NH1 1 ATOM 1919 N NH2 . ARG A 1 245 ? 15.597 -159.699 11.751 1.00 32.81 ? 303 ARG A NH2 1 ATOM 1920 N N . CYS A 1 246 ? 19.195 -154.098 14.253 1.00 21.21 ? 304 CYS A N 1 ATOM 1921 C CA . CYS A 1 246 ? 19.216 -154.430 15.665 1.00 24.03 ? 304 CYS A CA 1 ATOM 1922 C C . CYS A 1 246 ? 18.215 -155.536 15.974 1.00 17.34 ? 304 CYS A C 1 ATOM 1923 O O . CYS A 1 246 ? 17.004 -155.342 15.852 1.00 21.94 ? 304 CYS A O 1 ATOM 1924 C CB . CYS A 1 246 ? 18.911 -153.196 16.513 1.00 24.66 ? 304 CYS A CB 1 ATOM 1925 S SG . CYS A 1 246 ? 19.153 -153.479 18.288 1.00 36.67 ? 304 CYS A SG 1 ATOM 1926 N N . LEU A 1 247 ? 18.730 -156.696 16.369 1.00 20.35 ? 305 LEU A N 1 ATOM 1927 C CA . LEU A 1 247 ? 17.885 -157.805 16.796 1.00 23.23 ? 305 LEU A CA 1 ATOM 1928 C C . LEU A 1 247 ? 17.715 -157.786 18.306 1.00 19.87 ? 305 LEU A C 1 ATOM 1929 O O . LEU A 1 247 ? 18.677 -158.010 19.045 1.00 22.08 ? 305 LEU A O 1 ATOM 1930 C CB . LEU A 1 247 ? 18.481 -159.149 16.373 1.00 24.21 ? 305 LEU A CB 1 ATOM 1931 C CG . LEU A 1 247 ? 18.870 -159.352 14.910 1.00 34.84 ? 305 LEU A CG 1 ATOM 1932 C CD1 . LEU A 1 247 ? 18.905 -160.840 14.595 1.00 36.34 ? 305 LEU A CD1 1 ATOM 1933 C CD2 . LEU A 1 247 ? 17.927 -158.635 13.972 1.00 40.07 ? 305 LEU A CD2 1 ATOM 1934 N N . ASP A 1 248 ? 16.497 -157.523 18.768 1.00 23.00 ? 306 ASP A N 1 ATOM 1935 C CA . ASP A 1 248 ? 16.214 -157.623 20.190 1.00 23.74 ? 306 ASP A CA 1 ATOM 1936 C C . ASP A 1 248 ? 16.255 -159.103 20.553 1.00 25.98 ? 306 ASP A C 1 ATOM 1937 O O . ASP A 1 248 ? 16.123 -159.961 19.679 1.00 18.87 ? 306 ASP A O 1 ATOM 1938 C CB . ASP A 1 248 ? 14.867 -156.979 20.544 1.00 21.66 ? 306 ASP A CB 1 ATOM 1939 C CG . ASP A 1 248 ? 13.678 -157.799 20.085 1.00 29.74 ? 306 ASP A CG 1 ATOM 1940 O OD1 . ASP A 1 248 ? 13.256 -158.706 20.833 1.00 27.19 ? 306 ASP A OD1 1 ATOM 1941 O OD2 . ASP A 1 248 ? 13.152 -157.523 18.986 1.00 54.94 ? 306 ASP A OD2 1 ATOM 1942 N N . TYR A 1 249 ? 16.461 -159.398 21.832 1.00 18.05 ? 307 TYR A N 1 ATOM 1943 C CA . TYR A 1 249 ? 16.727 -160.766 22.278 1.00 23.13 ? 307 TYR A CA 1 ATOM 1944 C C . TYR A 1 249 ? 15.694 -161.796 21.815 1.00 16.95 ? 307 TYR A C 1 ATOM 1945 O O . TYR A 1 249 ? 16.029 -162.965 21.633 1.00 22.04 ? 307 TYR A O 1 ATOM 1946 C CB . TYR A 1 249 ? 16.816 -160.811 23.806 1.00 20.71 ? 307 TYR A CB 1 ATOM 1947 C CG . TYR A 1 249 ? 18.038 -160.137 24.403 1.00 17.89 ? 307 TYR A CG 1 ATOM 1948 C CD1 . TYR A 1 249 ? 19.212 -159.983 23.672 1.00 21.58 ? 307 TYR A CD1 1 ATOM 1949 C CD2 . TYR A 1 249 ? 18.018 -159.668 25.709 1.00 17.14 ? 307 TYR A CD2 1 ATOM 1950 C CE1 . TYR A 1 249 ? 20.325 -159.376 24.226 1.00 19.20 ? 307 TYR A CE1 1 ATOM 1951 C CE2 . TYR A 1 249 ? 19.123 -159.060 26.271 1.00 20.01 ? 307 TYR A CE2 1 ATOM 1952 C CZ . TYR A 1 249 ? 20.273 -158.917 25.529 1.00 13.23 ? 307 TYR A CZ 1 ATOM 1953 O OH . TYR A 1 249 ? 21.370 -158.311 26.097 1.00 20.25 ? 307 TYR A OH 1 ATOM 1954 N N . THR A 1 250 ? 14.447 -161.379 21.626 1.00 17.87 ? 308 THR A N 1 ATOM 1955 C CA . THR A 1 250 ? 13.404 -162.334 21.267 1.00 26.63 ? 308 THR A CA 1 ATOM 1956 C C . THR A 1 250 ? 13.623 -162.919 19.872 1.00 28.91 ? 308 THR A C 1 ATOM 1957 O O . THR A 1 250 ? 12.995 -163.912 19.516 1.00 28.43 ? 308 THR A O 1 ATOM 1958 C CB . THR A 1 250 ? 11.999 -161.704 21.318 1.00 26.71 ? 308 THR A CB 1 ATOM 1959 O OG1 . THR A 1 250 ? 11.866 -160.723 20.284 1.00 25.59 ? 308 THR A OG1 1 ATOM 1960 C CG2 . THR A 1 250 ? 11.744 -161.064 22.672 1.00 27.32 ? 308 THR A CG2 1 ATOM 1961 N N . GLU A 1 251 ? 14.513 -162.309 19.091 1.00 21.76 ? 309 GLU A N 1 ATOM 1962 C CA . GLU A 1 251 ? 14.814 -162.795 17.745 1.00 30.48 ? 309 GLU A CA 1 ATOM 1963 C C . GLU A 1 251 ? 15.972 -163.794 17.733 1.00 35.75 ? 309 GLU A C 1 ATOM 1964 O O . GLU A 1 251 ? 16.237 -164.427 16.711 1.00 32.91 ? 309 GLU A O 1 ATOM 1965 C CB . GLU A 1 251 ? 15.144 -161.627 16.809 1.00 26.51 ? 309 GLU A CB 1 ATOM 1966 C CG . GLU A 1 251 ? 13.946 -160.760 16.442 1.00 38.58 ? 309 GLU A CG 1 ATOM 1967 C CD . GLU A 1 251 ? 14.139 -160.009 15.135 1.00 49.99 ? 309 GLU A CD 1 ATOM 1968 O OE1 . GLU A 1 251 ? 14.489 -160.652 14.121 1.00 46.47 ? 309 GLU A OE1 1 ATOM 1969 O OE2 . GLU A 1 251 ? 13.940 -158.776 15.121 1.00 49.89 ? 309 GLU A OE2 1 ATOM 1970 N N . LEU A 1 252 ? 16.659 -163.932 18.864 1.00 29.61 ? 310 LEU A N 1 ATOM 1971 C CA . LEU A 1 252 ? 17.808 -164.829 18.964 1.00 30.74 ? 310 LEU A CA 1 ATOM 1972 C C . LEU A 1 252 ? 17.389 -166.184 19.532 1.00 35.31 ? 310 LEU A C 1 ATOM 1973 O O . LEU A 1 252 ? 16.538 -166.261 20.418 1.00 30.18 ? 310 LEU A O 1 ATOM 1974 C CB . LEU A 1 252 ? 18.899 -164.201 19.832 1.00 26.19 ? 310 LEU A CB 1 ATOM 1975 C CG . LEU A 1 252 ? 19.277 -162.760 19.478 1.00 28.31 ? 310 LEU A CG 1 ATOM 1976 C CD1 . LEU A 1 252 ? 20.333 -162.240 20.441 1.00 24.51 ? 310 LEU A CD1 1 ATOM 1977 C CD2 . LEU A 1 252 ? 19.765 -162.654 18.041 1.00 27.75 ? 310 LEU A CD2 1 ATOM 1978 N N . THR A 1 253 ? 18.000 -167.248 19.020 1.00 36.15 ? 311 THR A N 1 ATOM 1979 C CA . THR A 1 253 ? 17.581 -168.611 19.334 1.00 36.41 ? 311 THR A CA 1 ATOM 1980 C C . THR A 1 253 ? 17.940 -169.037 20.759 1.00 22.33 ? 311 THR A C 1 ATOM 1981 O O . THR A 1 253 ? 17.177 -169.758 21.401 1.00 29.80 ? 311 THR A O 1 ATOM 1982 C CB . THR A 1 253 ? 18.204 -169.614 18.340 1.00 38.39 ? 311 THR A CB 1 ATOM 1983 O OG1 . THR A 1 253 ? 17.791 -169.283 17.010 1.00 44.68 ? 311 THR A OG1 1 ATOM 1984 C CG2 . THR A 1 253 ? 17.772 -171.043 18.653 1.00 40.05 ? 311 THR A CG2 1 ATOM 1985 N N . ASP A 1 254 ? 19.095 -168.594 21.249 1.00 27.81 ? 312 ASP A N 1 ATOM 1986 C CA . ASP A 1 254 ? 19.555 -168.978 22.583 1.00 28.99 ? 312 ASP A CA 1 ATOM 1987 C C . ASP A 1 254 ? 18.844 -168.208 23.698 1.00 29.78 ? 312 ASP A C 1 ATOM 1988 O O . ASP A 1 254 ? 19.022 -168.510 24.879 1.00 30.11 ? 312 ASP A O 1 ATOM 1989 C CB . ASP A 1 254 ? 21.069 -168.769 22.707 1.00 36.41 ? 312 ASP A CB 1 ATOM 1990 C CG . ASP A 1 254 ? 21.870 -169.745 21.859 1.00 85.69 ? 312 ASP A CG 1 ATOM 1991 O OD1 . ASP A 1 254 ? 21.339 -170.822 21.513 1.00 79.62 ? 312 ASP A OD1 1 ATOM 1992 O OD2 . ASP A 1 254 ? 23.040 -169.436 21.544 1.00 69.02 ? 312 ASP A OD2 1 ATOM 1993 N N . THR A 1 255 ? 18.046 -167.214 23.327 1.00 24.56 ? 313 THR A N 1 ATOM 1994 C CA . THR A 1 255 ? 17.338 -166.400 24.307 1.00 20.06 ? 313 THR A CA 1 ATOM 1995 C C . THR A 1 255 ? 16.300 -167.226 25.058 1.00 27.26 ? 313 THR A C 1 ATOM 1996 O O . THR A 1 255 ? 15.624 -168.071 24.470 1.00 30.59 ? 313 THR A O 1 ATOM 1997 C CB . THR A 1 255 ? 16.656 -165.195 23.630 1.00 18.47 ? 313 THR A CB 1 ATOM 1998 O OG1 . THR A 1 255 ? 17.661 -164.317 23.111 1.00 18.22 ? 313 THR A OG1 1 ATOM 1999 C CG2 . THR A 1 255 ? 15.779 -164.419 24.609 1.00 19.02 ? 313 THR A CG2 1 ATOM 2000 N N . VAL A 1 256 ? 16.186 -166.979 26.360 1.00 20.10 ? 314 VAL A N 1 ATOM 2001 C CA . VAL A 1 256 ? 15.177 -167.644 27.179 1.00 15.86 ? 314 VAL A CA 1 ATOM 2002 C C . VAL A 1 256 ? 13.999 -166.697 27.385 1.00 21.29 ? 314 VAL A C 1 ATOM 2003 O O . VAL A 1 256 ? 14.177 -165.571 27.848 1.00 18.69 ? 314 VAL A O 1 ATOM 2004 C CB . VAL A 1 256 ? 15.747 -168.086 28.546 1.00 22.06 ? 314 VAL A CB 1 ATOM 2005 C CG1 . VAL A 1 256 ? 14.640 -168.589 29.461 1.00 28.09 ? 314 VAL A CG1 1 ATOM 2006 C CG2 . VAL A 1 256 ? 16.796 -169.171 28.354 1.00 26.33 ? 314 VAL A CG2 1 ATOM 2007 N N . ILE A 1 257 ? 12.803 -167.157 27.031 1.00 15.14 ? 315 ILE A N 1 ATOM 2008 C CA . ILE A 1 257 ? 11.590 -166.360 27.179 1.00 18.54 ? 315 ILE A CA 1 ATOM 2009 C C . ILE A 1 257 ? 10.676 -166.978 28.226 1.00 22.29 ? 315 ILE A C 1 ATOM 2010 O O . ILE A 1 257 ? 10.310 -168.150 28.127 1.00 19.65 ? 315 ILE A O 1 ATOM 2011 C CB . ILE A 1 257 ? 10.831 -166.233 25.848 1.00 16.82 ? 315 ILE A CB 1 ATOM 2012 C CG1 . ILE A 1 257 ? 11.691 -165.472 24.834 1.00 24.88 ? 315 ILE A CG1 1 ATOM 2013 C CG2 . ILE A 1 257 ? 9.490 -165.516 26.059 1.00 16.96 ? 315 ILE A CG2 1 ATOM 2014 C CD1 . ILE A 1 257 ? 11.106 -165.406 23.443 1.00 30.61 ? 315 ILE A CD1 1 ATOM 2015 N N . GLU A 1 258 ? 10.305 -166.183 29.225 1.00 15.53 ? 316 GLU A N 1 ATOM 2016 C CA . GLU A 1 258 ? 9.438 -166.668 30.293 1.00 18.21 ? 316 GLU A CA 1 ATOM 2017 C C . GLU A 1 258 ? 8.255 -165.739 30.532 1.00 23.34 ? 316 GLU A C 1 ATOM 2018 O O . GLU A 1 258 ? 8.354 -164.526 30.347 1.00 21.67 ? 316 GLU A O 1 ATOM 2019 C CB . GLU A 1 258 ? 10.235 -166.836 31.588 1.00 18.33 ? 316 GLU A CB 1 ATOM 2020 C CG . GLU A 1 258 ? 11.489 -167.676 31.424 1.00 28.50 ? 316 GLU A CG 1 ATOM 2021 C CD . GLU A 1 258 ? 12.238 -167.865 32.727 1.00 38.20 ? 316 GLU A CD 1 ATOM 2022 O OE1 . GLU A 1 258 ? 13.435 -168.213 32.678 1.00 38.30 ? 316 GLU A OE1 1 ATOM 2023 O OE2 . GLU A 1 258 ? 11.632 -167.665 33.799 1.00 38.09 ? 316 GLU A OE2 1 ATOM 2024 N N . ARG A 1 259 ? 7.135 -166.327 30.939 1.00 22.79 ? 317 ARG A N 1 ATOM 2025 C CA . ARG A 1 259 ? 5.958 -165.563 31.322 1.00 22.21 ? 317 ARG A CA 1 ATOM 2026 C C . ARG A 1 259 ? 6.188 -164.904 32.676 1.00 22.59 ? 317 ARG A C 1 ATOM 2027 O O . ARG A 1 259 ? 6.847 -165.475 33.545 1.00 21.87 ? 317 ARG A O 1 ATOM 2028 C CB . ARG A 1 259 ? 4.722 -166.463 31.384 1.00 23.88 ? 317 ARG A CB 1 ATOM 2029 C CG . ARG A 1 259 ? 4.318 -167.073 30.051 1.00 22.65 ? 317 ARG A CG 1 ATOM 2030 C CD . ARG A 1 259 ? 3.227 -168.120 30.241 0.68 20.15 ? 317 ARG A CD 1 ATOM 2031 N NE . ARG A 1 259 ? 3.694 -169.261 31.027 0.86 20.67 ? 317 ARG A NE 1 ATOM 2032 C CZ . ARG A 1 259 ? 4.413 -170.267 30.537 0.80 26.69 ? 317 ARG A CZ 1 ATOM 2033 N NH1 . ARG A 1 259 ? 4.793 -171.258 31.329 0.98 26.15 ? 317 ARG A NH1 1 ATOM 2034 N NH2 . ARG A 1 259 ? 4.760 -170.284 29.256 0.88 16.33 ? 317 ARG A NH2 1 ATOM 2035 N N . VAL A 1 260 ? 5.648 -163.702 32.846 1.00 18.94 ? 318 VAL A N 1 ATOM 2036 C CA . VAL A 1 260 ? 5.716 -162.996 34.119 1.00 19.95 ? 318 VAL A CA 1 ATOM 2037 C C . VAL A 1 260 ? 4.434 -162.211 34.342 1.00 20.40 ? 318 VAL A C 1 ATOM 2038 O O . VAL A 1 260 ? 3.756 -161.832 33.389 1.00 20.61 ? 318 VAL A O 1 ATOM 2039 C CB . VAL A 1 260 ? 6.920 -162.033 34.181 1.00 26.77 ? 318 VAL A CB 1 ATOM 2040 C CG1 . VAL A 1 260 ? 8.224 -162.811 34.221 1.00 20.87 ? 318 VAL A CG1 1 ATOM 2041 C CG2 . VAL A 1 260 ? 6.900 -161.063 33.001 1.00 16.55 ? 318 VAL A CG2 1 ATOM 2042 N N . GLU A 1 261 ? 4.107 -161.976 35.608 1.00 16.86 ? 319 GLU A N 1 ATOM 2043 C CA . GLU A 1 261 ? 2.937 -161.186 35.969 1.00 24.16 ? 319 GLU A CA 1 ATOM 2044 C C . GLU A 1 261 ? 3.269 -159.699 36.023 1.00 26.72 ? 319 GLU A C 1 ATOM 2045 O O . GLU A 1 261 ? 2.369 -158.859 36.010 1.00 22.53 ? 319 GLU A O 1 ATOM 2046 C CB . GLU A 1 261 ? 2.386 -161.631 37.325 1.00 28.17 ? 319 GLU A CB 1 ATOM 2047 C CG . GLU A 1 261 ? 2.073 -163.114 37.432 1.00 38.25 ? 319 GLU A CG 1 ATOM 2048 C CD . GLU A 1 261 ? 1.785 -163.535 38.861 0.56 30.49 ? 319 GLU A CD 1 ATOM 2049 O OE1 . GLU A 1 261 ? 0.705 -163.184 39.380 0.83 30.40 ? 319 GLU A OE1 1 ATOM 2050 O OE2 . GLU A 1 261 ? 2.645 -164.208 39.468 0.73 21.93 ? 319 GLU A OE2 1 ATOM 2051 N N . SER A 1 262 ? 4.560 -159.383 36.096 1.00 20.31 ? 320 SER A N 1 ATOM 2052 C CA . SER A 1 262 ? 5.008 -158.005 36.283 1.00 21.78 ? 320 SER A CA 1 ATOM 2053 C C . SER A 1 262 ? 6.454 -157.822 35.836 1.00 18.48 ? 320 SER A C 1 ATOM 2054 O O . SER A 1 262 ? 7.197 -158.791 35.694 1.00 16.80 ? 320 SER A O 1 ATOM 2055 C CB . SER A 1 262 ? 4.873 -157.600 37.751 1.00 24.16 ? 320 SER A CB 1 ATOM 2056 O OG . SER A 1 262 ? 5.896 -158.200 38.530 1.00 23.50 ? 320 SER A OG 1 ATOM 2057 N N . LYS A 1 263 ? 6.853 -156.572 35.626 1.00 18.87 ? 321 LYS A N 1 ATOM 2058 C CA . LYS A 1 263 ? 8.209 -156.272 35.180 1.00 17.74 ? 321 LYS A CA 1 ATOM 2059 C C . LYS A 1 263 ? 9.233 -156.518 36.296 1.00 11.98 ? 321 LYS A C 1 ATOM 2060 O O . LYS A 1 263 ? 10.393 -156.867 36.032 1.00 21.08 ? 321 LYS A O 1 ATOM 2061 C CB . LYS A 1 263 ? 8.288 -154.825 34.675 1.00 21.53 ? 321 LYS A CB 1 ATOM 2062 C CG . LYS A 1 263 ? 7.794 -153.775 35.660 1.00 21.43 ? 321 LYS A CG 1 ATOM 2063 C CD . LYS A 1 263 ? 8.000 -152.352 35.135 1.00 34.86 ? 321 LYS A CD 1 ATOM 2064 C CE . LYS A 1 263 ? 7.205 -152.074 33.866 1.00 24.64 ? 321 LYS A CE 1 ATOM 2065 N NZ . LYS A 1 263 ? 5.732 -152.155 34.078 1.00 46.73 ? 321 LYS A NZ 1 ATOM 2066 N N . ALA A 1 264 ? 8.796 -156.353 37.541 1.00 15.05 ? 322 ALA A N 1 ATOM 2067 C CA . ALA A 1 264 ? 9.649 -156.618 38.698 1.00 18.70 ? 322 ALA A CA 1 ATOM 2068 C C . ALA A 1 264 ? 10.103 -158.078 38.732 1.00 13.26 ? 322 ALA A C 1 ATOM 2069 O O . ALA A 1 264 ? 11.255 -158.372 39.062 1.00 16.41 ? 322 ALA A O 1 ATOM 2070 C CB . ALA A 1 264 ? 8.920 -156.265 39.979 1.00 20.41 ? 322 ALA A CB 1 ATOM 2071 N N . GLN A 1 265 ? 9.195 -158.987 38.391 1.00 13.47 ? 323 GLN A N 1 ATOM 2072 C CA . GLN A 1 265 ? 9.526 -160.408 38.297 1.00 21.86 ? 323 GLN A CA 1 ATOM 2073 C C . GLN A 1 265 ? 10.632 -160.645 37.273 1.00 12.95 ? 323 GLN A C 1 ATOM 2074 O O . GLN A 1 265 ? 11.529 -161.467 37.483 1.00 15.10 ? 323 GLN A O 1 ATOM 2075 C CB . GLN A 1 265 ? 8.288 -161.227 37.926 1.00 17.26 ? 323 GLN A CB 1 ATOM 2076 C CG . GLN A 1 265 ? 7.300 -161.400 39.070 1.00 26.62 ? 323 GLN A CG 1 ATOM 2077 C CD . GLN A 1 265 ? 6.163 -162.351 38.733 1.00 38.75 ? 323 GLN A CD 1 ATOM 2078 O OE1 . GLN A 1 265 ? 6.075 -162.868 37.620 1.00 27.06 ? 323 GLN A OE1 1 ATOM 2079 N NE2 . GLN A 1 265 ? 5.287 -162.590 39.704 1.00 39.32 ? 323 GLN A NE2 1 ATOM 2080 N N . CYS A 1 266 ? 10.562 -159.922 36.159 1.00 15.15 ? 324 CYS A N 1 ATOM 2081 C CA . CYS A 1 266 ? 11.584 -160.020 35.125 1.00 14.43 ? 324 CYS A CA 1 ATOM 2082 C C . CYS A 1 266 ? 12.913 -159.487 35.643 1.00 15.00 ? 324 CYS A C 1 ATOM 2083 O O . CYS A 1 266 ? 13.972 -160.113 35.461 1.00 14.48 ? 324 CYS A O 1 ATOM 2084 C CB . CYS A 1 266 ? 11.167 -159.250 33.873 1.00 15.80 ? 324 CYS A CB 1 ATOM 2085 S SG . CYS A 1 266 ? 12.323 -159.432 32.509 1.00 22.74 ? 324 CYS A SG 1 ATOM 2086 N N . TRP A 1 267 ? 12.853 -158.326 36.288 1.00 14.73 ? 325 TRP A N 1 ATOM 2087 C CA . TRP A 1 267 ? 14.031 -157.763 36.934 1.00 13.03 ? 325 TRP A CA 1 ATOM 2088 C C . TRP A 1 267 ? 14.669 -158.769 37.895 1.00 17.17 ? 325 TRP A C 1 ATOM 2089 O O . TRP A 1 267 ? 15.884 -158.950 37.883 1.00 13.64 ? 325 TRP A O 1 ATOM 2090 C CB . TRP A 1 267 ? 13.667 -156.476 37.674 1.00 15.23 ? 325 TRP A CB 1 ATOM 2091 C CG . TRP A 1 267 ? 14.770 -155.935 38.538 1.00 12.68 ? 325 TRP A CG 1 ATOM 2092 C CD1 . TRP A 1 267 ? 15.937 -155.362 38.119 1.00 12.83 ? 325 TRP A CD1 1 ATOM 2093 C CD2 . TRP A 1 267 ? 14.801 -155.904 39.970 1.00 15.85 ? 325 TRP A CD2 1 ATOM 2094 N NE1 . TRP A 1 267 ? 16.693 -154.982 39.201 1.00 15.78 ? 325 TRP A NE1 1 ATOM 2095 C CE2 . TRP A 1 267 ? 16.018 -155.303 40.349 1.00 15.05 ? 325 TRP A CE2 1 ATOM 2096 C CE3 . TRP A 1 267 ? 13.920 -156.329 40.968 1.00 15.29 ? 325 TRP A CE3 1 ATOM 2097 C CZ2 . TRP A 1 267 ? 16.375 -155.116 41.682 1.00 14.51 ? 325 TRP A CZ2 1 ATOM 2098 C CZ3 . TRP A 1 267 ? 14.278 -156.143 42.292 1.00 18.27 ? 325 TRP A CZ3 1 ATOM 2099 C CH2 . TRP A 1 267 ? 15.494 -155.543 42.636 1.00 16.18 ? 325 TRP A CH2 1 ATOM 2100 N N . VAL A 1 268 ? 13.855 -159.428 38.716 1.00 12.21 ? 326 VAL A N 1 ATOM 2101 C CA . VAL A 1 268 ? 14.367 -160.471 39.608 1.00 12.55 ? 326 VAL A CA 1 ATOM 2102 C C . VAL A 1 268 ? 14.974 -161.625 38.810 1.00 16.99 ? 326 VAL A C 1 ATOM 2103 O O . VAL A 1 268 ? 16.052 -162.138 39.142 1.00 17.11 ? 326 VAL A O 1 ATOM 2104 C CB . VAL A 1 268 ? 13.257 -161.015 40.535 1.00 20.34 ? 326 VAL A CB 1 ATOM 2105 C CG1 . VAL A 1 268 ? 13.727 -162.255 41.312 1.00 15.62 ? 326 VAL A CG1 1 ATOM 2106 C CG2 . VAL A 1 268 ? 12.802 -159.925 41.506 1.00 18.60 ? 326 VAL A CG2 1 ATOM 2107 N N . LYS A 1 269 ? 14.273 -162.040 37.759 1.00 17.93 ? 327 LYS A N 1 ATOM 2108 C CA . LYS A 1 269 ? 14.745 -163.132 36.913 1.00 17.21 ? 327 LYS A CA 1 ATOM 2109 C C . LYS A 1 269 ? 16.091 -162.858 36.267 1.00 17.21 ? 327 LYS A C 1 ATOM 2110 O O . LYS A 1 269 ? 16.890 -163.780 36.105 1.00 16.55 ? 327 LYS A O 1 ATOM 2111 C CB . LYS A 1 269 ? 13.727 -163.443 35.819 1.00 23.07 ? 327 LYS A CB 1 ATOM 2112 C CG . LYS A 1 269 ? 12.612 -164.368 36.266 1.00 23.57 ? 327 LYS A CG 1 ATOM 2113 C CD . LYS A 1 269 ? 11.611 -164.601 35.145 1.00 27.31 ? 327 LYS A CD 1 ATOM 2114 C CE . LYS A 1 269 ? 10.375 -165.335 35.647 1.00 29.30 ? 327 LYS A CE 1 ATOM 2115 N NZ . LYS A 1 269 ? 10.664 -166.748 36.010 1.00 33.46 ? 327 LYS A NZ 1 ATOM 2116 N N . THR A 1 270 ? 16.353 -161.616 35.866 1.00 16.80 ? 328 THR A N 1 ATOM 2117 C CA . THR A 1 270 ? 17.672 -161.322 35.302 1.00 11.75 ? 328 THR A CA 1 ATOM 2118 C C . THR A 1 270 ? 18.808 -161.606 36.287 1.00 15.11 ? 328 THR A C 1 ATOM 2119 O O . THR A 1 270 ? 19.943 -161.832 35.874 1.00 18.73 ? 328 THR A O 1 ATOM 2120 C CB . THR A 1 270 ? 17.794 -159.860 34.828 1.00 16.82 ? 328 THR A CB 1 ATOM 2121 O OG1 . THR A 1 270 ? 17.636 -158.966 35.937 1.00 27.96 ? 328 THR A OG1 1 ATOM 2122 C CG2 . THR A 1 270 ? 16.752 -159.560 33.764 1.00 12.87 ? 328 THR A CG2 1 ATOM 2123 N N . PHE A 1 271 ? 18.503 -161.597 37.582 1.00 15.10 ? 329 PHE A N 1 ATOM 2124 C CA . PHE A 1 271 ? 19.501 -161.885 38.608 1.00 14.30 ? 329 PHE A CA 1 ATOM 2125 C C . PHE A 1 271 ? 19.452 -163.332 39.084 1.00 18.09 ? 329 PHE A C 1 ATOM 2126 O O . PHE A 1 271 ? 20.491 -163.922 39.387 1.00 14.19 ? 329 PHE A O 1 ATOM 2127 C CB . PHE A 1 271 ? 19.313 -160.960 39.811 1.00 16.03 ? 329 PHE A CB 1 ATOM 2128 C CG . PHE A 1 271 ? 20.213 -161.282 40.969 1.00 10.51 ? 329 PHE A CG 1 ATOM 2129 C CD1 . PHE A 1 271 ? 21.548 -160.914 40.948 1.00 10.71 ? 329 PHE A CD1 1 ATOM 2130 C CD2 . PHE A 1 271 ? 19.724 -161.947 42.081 1.00 18.12 ? 329 PHE A CD2 1 ATOM 2131 C CE1 . PHE A 1 271 ? 22.378 -161.205 42.010 1.00 13.11 ? 329 PHE A CE1 1 ATOM 2132 C CE2 . PHE A 1 271 ? 20.551 -162.239 43.148 1.00 15.81 ? 329 PHE A CE2 1 ATOM 2133 C CZ . PHE A 1 271 ? 21.879 -161.867 43.112 1.00 12.33 ? 329 PHE A CZ 1 ATOM 2134 N N . GLU A 1 272 ? 18.252 -163.897 39.170 1.00 15.35 ? 330 GLU A N 1 ATOM 2135 C CA . GLU A 1 272 ? 18.098 -165.228 39.760 1.00 17.82 ? 330 GLU A CA 1 ATOM 2136 C C . GLU A 1 272 ? 18.056 -166.421 38.792 1.00 25.13 ? 330 GLU A C 1 ATOM 2137 O O . GLU A 1 272 ? 18.069 -167.564 39.246 1.00 20.62 ? 330 GLU A O 1 ATOM 2138 C CB . GLU A 1 272 ? 16.833 -165.251 40.620 1.00 16.50 ? 330 GLU A CB 1 ATOM 2139 C CG . GLU A 1 272 ? 16.973 -164.432 41.899 1.00 25.11 ? 330 GLU A CG 1 ATOM 2140 C CD . GLU A 1 272 ? 15.773 -164.553 42.813 1.00 31.46 ? 330 GLU A CD 1 ATOM 2141 O OE1 . GLU A 1 272 ? 15.781 -163.916 43.888 1.00 32.37 ? 330 GLU A OE1 1 ATOM 2142 O OE2 . GLU A 1 272 ? 14.823 -165.286 42.459 1.00 31.99 ? 330 GLU A OE2 1 ATOM 2143 N N . ASN A 1 273 ? 18.014 -166.188 37.482 1.00 19.05 ? 331 ASN A N 1 ATOM 2144 C CA . ASN A 1 273 ? 17.962 -167.311 36.542 1.00 15.78 ? 331 ASN A CA 1 ATOM 2145 C C . ASN A 1 273 ? 19.262 -168.117 36.587 1.00 19.54 ? 331 ASN A C 1 ATOM 2146 O O . ASN A 1 273 ? 20.308 -167.602 36.982 1.00 21.26 ? 331 ASN A O 1 ATOM 2147 C CB . ASN A 1 273 ? 17.681 -166.830 35.116 1.00 15.09 ? 331 ASN A CB 1 ATOM 2148 C CG . ASN A 1 273 ? 18.894 -166.214 34.453 1.00 16.40 ? 331 ASN A CG 1 ATOM 2149 O OD1 . ASN A 1 273 ? 19.772 -166.921 33.958 1.00 20.57 ? 331 ASN A OD1 1 ATOM 2150 N ND2 . ASN A 1 273 ? 18.944 -164.887 34.426 1.00 22.22 ? 331 ASN A ND2 1 ATOM 2151 N N . ASP A 1 274 ? 19.190 -169.380 36.177 1.00 20.03 ? 332 ASP A N 1 ATOM 2152 C CA . ASP A 1 274 ? 20.287 -170.326 36.396 1.00 25.36 ? 332 ASP A CA 1 ATOM 2153 C C . ASP A 1 274 ? 21.555 -170.040 35.586 1.00 25.63 ? 332 ASP A C 1 ATOM 2154 O O . ASP A 1 274 ? 22.604 -170.628 35.853 1.00 28.71 ? 332 ASP A O 1 ATOM 2155 C CB . ASP A 1 274 ? 19.810 -171.756 36.101 1.00 40.29 ? 332 ASP A CB 1 ATOM 2156 C CG . ASP A 1 274 ? 19.227 -171.915 34.702 1.00 81.47 ? 332 ASP A CG 1 ATOM 2157 O OD1 . ASP A 1 274 ? 19.626 -171.170 33.782 1.00 72.35 ? 332 ASP A OD1 1 ATOM 2158 O OD2 . ASP A 1 274 ? 18.366 -172.803 34.522 1.00 90.69 ? 332 ASP A OD2 1 ATOM 2159 N N . GLY A 1 275 ? 21.464 -169.143 34.608 1.00 22.10 ? 333 GLY A N 1 ATOM 2160 C CA . GLY A 1 275 ? 22.590 -168.852 33.734 1.00 15.77 ? 333 GLY A CA 1 ATOM 2161 C C . GLY A 1 275 ? 23.382 -167.608 34.103 1.00 16.84 ? 333 GLY A C 1 ATOM 2162 O O . GLY A 1 275 ? 24.367 -167.275 33.441 1.00 18.16 ? 333 GLY A O 1 ATOM 2163 N N . VAL A 1 276 ? 22.958 -166.917 35.156 1.00 17.47 ? 334 VAL A N 1 ATOM 2164 C CA . VAL A 1 276 ? 23.607 -165.675 35.565 1.00 17.32 ? 334 VAL A CA 1 ATOM 2165 C C . VAL A 1 276 ? 25.047 -165.936 35.986 1.00 21.44 ? 334 VAL A C 1 ATOM 2166 O O . VAL A 1 276 ? 25.355 -166.992 36.537 1.00 17.95 ? 334 VAL A O 1 ATOM 2167 C CB . VAL A 1 276 ? 22.842 -165.001 36.722 1.00 17.33 ? 334 VAL A CB 1 ATOM 2168 C CG1 . VAL A 1 276 ? 23.558 -163.742 37.192 1.00 16.83 ? 334 VAL A CG1 1 ATOM 2169 C CG2 . VAL A 1 276 ? 21.429 -164.659 36.282 1.00 21.30 ? 334 VAL A CG2 1 ATOM 2170 N N . ALA A 1 277 ? 25.922 -164.970 35.720 1.00 16.48 ? 335 ALA A N 1 ATOM 2171 C CA . ALA A 1 277 ? 27.331 -165.086 36.082 1.00 21.04 ? 335 ALA A CA 1 ATOM 2172 C C . ALA A 1 277 ? 27.485 -165.423 37.564 1.00 24.21 ? 335 ALA A C 1 ATOM 2173 O O . ALA A 1 277 ? 27.030 -164.673 38.428 1.00 18.45 ? 335 ALA A O 1 ATOM 2174 C CB . ALA A 1 277 ? 28.066 -163.802 35.754 1.00 18.46 ? 335 ALA A CB 1 ATOM 2175 N N . SER A 1 278 ? 28.120 -166.558 37.844 1.00 22.31 ? 336 SER A N 1 ATOM 2176 C CA . SER A 1 278 ? 28.293 -167.036 39.213 1.00 23.36 ? 336 SER A CA 1 ATOM 2177 C C . SER A 1 278 ? 29.640 -167.727 39.388 1.00 26.80 ? 336 SER A C 1 ATOM 2178 O O . SER A 1 278 ? 30.075 -168.479 38.519 1.00 20.25 ? 336 SER A O 1 ATOM 2179 C CB . SER A 1 278 ? 27.166 -167.998 39.586 1.00 20.18 ? 336 SER A CB 1 ATOM 2180 O OG . SER A 1 278 ? 27.357 -168.528 40.885 1.00 27.09 ? 336 SER A OG 1 ATOM 2181 N N . ASP A 1 279 ? 30.290 -167.471 40.519 1.00 24.12 ? 337 ASP A N 1 ATOM 2182 C CA . ASP A 1 279 ? 31.588 -168.069 40.814 1.00 20.22 ? 337 ASP A CA 1 ATOM 2183 C C . ASP A 1 279 ? 31.450 -169.212 41.818 1.00 23.94 ? 337 ASP A C 1 ATOM 2184 O O . ASP A 1 279 ? 32.444 -169.718 42.334 1.00 23.26 ? 337 ASP A O 1 ATOM 2185 C CB . ASP A 1 279 ? 32.556 -167.008 41.348 1.00 18.98 ? 337 ASP A CB 1 ATOM 2186 C CG . ASP A 1 279 ? 32.798 -165.885 40.353 1.00 28.98 ? 337 ASP A CG 1 ATOM 2187 O OD1 . ASP A 1 279 ? 32.587 -166.104 39.142 1.00 28.02 ? 337 ASP A OD1 1 ATOM 2188 O OD2 . ASP A 1 279 ? 33.205 -164.783 40.781 1.00 27.91 ? 337 ASP A OD2 1 ATOM 2189 N N . GLN A 1 280 ? 30.213 -169.619 42.086 1.00 17.24 ? 338 GLN A N 1 ATOM 2190 C CA . GLN A 1 280 ? 29.948 -170.699 43.031 1.00 24.19 ? 338 GLN A CA 1 ATOM 2191 C C . GLN A 1 280 ? 30.476 -172.032 42.493 1.00 33.43 ? 338 GLN A C 1 ATOM 2192 O O . GLN A 1 280 ? 30.344 -172.305 41.300 1.00 23.46 ? 338 GLN A O 1 ATOM 2193 C CB . GLN A 1 280 ? 28.448 -170.803 43.304 1.00 23.18 ? 338 GLN A CB 1 ATOM 2194 C CG . GLN A 1 280 ? 28.072 -171.784 44.406 1.00 26.61 ? 338 GLN A CG 1 ATOM 2195 C CD . GLN A 1 280 ? 28.331 -171.238 45.799 1.00 38.99 ? 338 GLN A CD 1 ATOM 2196 O OE1 . GLN A 1 280 ? 28.824 -170.122 45.962 1.00 27.54 ? 338 GLN A OE1 1 ATOM 2197 N NE2 . GLN A 1 280 ? 28.007 -172.032 46.814 1.00 33.94 ? 338 GLN A NE2 1 ATOM 2198 N N . PRO A 1 281 ? 31.075 -172.868 43.364 1.00 41.04 ? 339 PRO A N 1 ATOM 2199 C CA . PRO A 1 281 ? 31.546 -174.186 42.915 1.00 41.77 ? 339 PRO A CA 1 ATOM 2200 C C . PRO A 1 281 ? 30.437 -175.037 42.310 1.00 32.26 ? 339 PRO A C 1 ATOM 2201 O O . PRO A 1 281 ? 29.309 -174.953 42.796 1.00 30.09 ? 339 PRO A O 1 ATOM 2202 C CB . PRO A 1 281 ? 32.078 -174.831 44.203 1.00 40.17 ? 339 PRO A CB 1 ATOM 2203 C CG . PRO A 1 281 ? 31.477 -174.041 45.319 1.00 42.30 ? 339 PRO A CG 1 ATOM 2204 C CD . PRO A 1 281 ? 31.369 -172.653 44.791 1.00 29.69 ? 339 PRO A CD 1 ATOM 2205 N N . ASP A 1 289 ? 36.592 -177.194 43.131 1.00 55.00 ? 360 ASP A N 1 ATOM 2206 C CA . ASP A 1 289 ? 36.158 -176.395 41.990 1.00 53.97 ? 360 ASP A CA 1 ATOM 2207 C C . ASP A 1 289 ? 35.992 -174.928 42.384 1.00 49.11 ? 360 ASP A C 1 ATOM 2208 O O . ASP A 1 289 ? 35.280 -174.614 43.336 1.00 50.72 ? 360 ASP A O 1 ATOM 2209 C CB . ASP A 1 289 ? 34.844 -176.939 41.427 1.00 60.90 ? 360 ASP A CB 1 ATOM 2210 C CG . ASP A 1 289 ? 34.480 -176.320 40.092 1.00 56.40 ? 360 ASP A CG 1 ATOM 2211 O OD1 . ASP A 1 289 ? 35.389 -176.122 39.257 1.00 58.36 ? 360 ASP A OD1 1 ATOM 2212 O OD2 . ASP A 1 289 ? 33.284 -176.028 39.879 1.00 57.50 ? 360 ASP A OD2 1 ATOM 2213 N N . GLN A 1 290 ? 36.649 -174.038 41.646 1.00 43.47 ? 361 GLN A N 1 ATOM 2214 C CA . GLN A 1 290 ? 36.587 -172.603 41.917 1.00 36.96 ? 361 GLN A CA 1 ATOM 2215 C C . GLN A 1 290 ? 36.429 -171.814 40.619 1.00 30.67 ? 361 GLN A C 1 ATOM 2216 O O . GLN A 1 290 ? 37.383 -171.201 40.139 1.00 34.43 ? 361 GLN A O 1 ATOM 2217 C CB . GLN A 1 290 ? 37.837 -172.151 42.672 1.00 31.17 ? 361 GLN A CB 1 ATOM 2218 C CG . GLN A 1 290 ? 37.936 -172.744 44.072 1.00 31.38 ? 361 GLN A CG 1 ATOM 2219 C CD . GLN A 1 290 ? 39.089 -172.175 44.874 1.00 40.64 ? 361 GLN A CD 1 ATOM 2220 O OE1 . GLN A 1 290 ? 39.908 -171.417 44.356 1.00 46.43 ? 361 GLN A OE1 1 ATOM 2221 N NE2 . GLN A 1 290 ? 39.154 -172.535 46.151 1.00 36.40 ? 361 GLN A NE2 1 ATOM 2222 N N . PRO A 1 291 ? 35.213 -171.823 40.050 1.00 30.71 ? 362 PRO A N 1 ATOM 2223 C CA . PRO A 1 291 ? 34.971 -171.191 38.748 1.00 28.86 ? 362 PRO A CA 1 ATOM 2224 C C . PRO A 1 291 ? 35.083 -169.668 38.788 1.00 28.02 ? 362 PRO A C 1 ATOM 2225 O O . PRO A 1 291 ? 34.651 -169.038 39.756 1.00 25.40 ? 362 PRO A O 1 ATOM 2226 C CB . PRO A 1 291 ? 33.534 -171.613 38.404 1.00 31.71 ? 362 PRO A CB 1 ATOM 2227 C CG . PRO A 1 291 ? 33.154 -172.658 39.406 1.00 37.72 ? 362 PRO A CG 1 ATOM 2228 C CD . PRO A 1 291 ? 33.983 -172.403 40.612 1.00 33.16 ? 362 PRO A CD 1 ATOM 2229 N N . HIS A 1 292 ? 35.667 -169.099 37.739 1.00 28.34 ? 363 HIS A N 1 ATOM 2230 C CA . HIS A 1 292 ? 35.724 -167.653 37.557 1.00 28.09 ? 363 HIS A CA 1 ATOM 2231 C C . HIS A 1 292 ? 34.937 -167.269 36.311 1.00 28.44 ? 363 HIS A C 1 ATOM 2232 O O . HIS A 1 292 ? 35.442 -167.368 35.194 1.00 29.03 ? 363 HIS A O 1 ATOM 2233 C CB . HIS A 1 292 ? 37.173 -167.175 37.441 1.00 27.83 ? 363 HIS A CB 1 ATOM 2234 C CG . HIS A 1 292 ? 37.934 -167.232 38.729 1.00 35.94 ? 363 HIS A CG 1 ATOM 2235 N ND1 . HIS A 1 292 ? 39.269 -166.900 38.818 1.00 41.30 ? 363 HIS A ND1 1 ATOM 2236 C CD2 . HIS A 1 292 ? 37.547 -167.576 39.980 1.00 42.77 ? 363 HIS A CD2 1 ATOM 2237 C CE1 . HIS A 1 292 ? 39.672 -167.040 40.069 1.00 37.35 ? 363 HIS A CE1 1 ATOM 2238 N NE2 . HIS A 1 292 ? 38.646 -167.448 40.794 1.00 38.73 ? 363 HIS A NE2 1 ATOM 2239 N N . SER A 1 293 ? 33.695 -166.841 36.510 1.00 25.85 ? 364 SER A N 1 ATOM 2240 C CA . SER A 1 293 ? 32.825 -166.464 35.402 1.00 23.35 ? 364 SER A CA 1 ATOM 2241 C C . SER A 1 293 ? 33.366 -165.260 34.641 1.00 27.09 ? 364 SER A C 1 ATOM 2242 O O . SER A 1 293 ? 33.137 -165.120 33.442 1.00 25.84 ? 364 SER A O 1 ATOM 2243 C CB . SER A 1 293 ? 31.419 -166.149 35.912 1.00 24.46 ? 364 SER A CB 1 ATOM 2244 O OG . SER A 1 293 ? 31.431 -164.996 36.736 1.00 23.08 ? 364 SER A OG 1 ATOM 2245 N N . GLY A 1 294 ? 34.075 -164.385 35.346 1.00 25.32 ? 365 GLY A N 1 ATOM 2246 C CA . GLY A 1 294 ? 34.582 -163.165 34.745 1.00 25.81 ? 365 GLY A CA 1 ATOM 2247 C C . GLY A 1 294 ? 33.468 -162.239 34.289 1.00 22.72 ? 365 GLY A C 1 ATOM 2248 O O . GLY A 1 294 ? 33.691 -161.348 33.469 1.00 24.18 ? 365 GLY A O 1 ATOM 2249 N N . GLY A 1 295 ? 32.264 -162.451 34.815 1.00 19.09 ? 366 GLY A N 1 ATOM 2250 C CA . GLY A 1 295 ? 31.115 -161.636 34.456 1.00 24.05 ? 366 GLY A CA 1 ATOM 2251 C C . GLY A 1 295 ? 30.332 -162.152 33.264 1.00 22.10 ? 366 GLY A C 1 ATOM 2252 O O . GLY A 1 295 ? 29.340 -161.545 32.865 1.00 20.97 ? 366 GLY A O 1 ATOM 2253 N N . VAL A 1 296 ? 30.768 -163.269 32.692 1.00 23.29 ? 367 VAL A N 1 ATOM 2254 C CA . VAL A 1 296 ? 30.045 -163.881 31.583 1.00 21.24 ? 367 VAL A CA 1 ATOM 2255 C C . VAL A 1 296 ? 28.835 -164.650 32.105 1.00 22.64 ? 367 VAL A C 1 ATOM 2256 O O . VAL A 1 296 ? 28.942 -165.387 33.084 1.00 25.89 ? 367 VAL A O 1 ATOM 2257 C CB . VAL A 1 296 ? 30.949 -164.835 30.777 1.00 30.80 ? 367 VAL A CB 1 ATOM 2258 C CG1 . VAL A 1 296 ? 30.178 -165.466 29.628 1.00 28.20 ? 367 VAL A CG1 1 ATOM 2259 C CG2 . VAL A 1 296 ? 32.169 -164.093 30.249 1.00 22.88 ? 367 VAL A CG2 1 ATOM 2260 N N . GLY A 1 297 ? 27.686 -164.477 31.454 1.00 17.57 ? 368 GLY A N 1 ATOM 2261 C CA . GLY A 1 297 ? 26.489 -165.208 31.830 1.00 19.12 ? 368 GLY A CA 1 ATOM 2262 C C . GLY A 1 297 ? 25.203 -164.569 31.341 1.00 18.53 ? 368 GLY A C 1 ATOM 2263 O O . GLY A 1 297 ? 25.215 -163.492 30.744 1.00 13.07 ? 368 GLY A O 1 ATOM 2264 N N . ARG A 1 298 ? 24.087 -165.243 31.599 1.00 20.32 ? 369 ARG A N 1 ATOM 2265 C CA A ARG A 1 298 ? 22.778 -164.749 31.194 0.54 16.63 ? 369 ARG A CA 1 ATOM 2266 C CA B ARG A 1 298 ? 22.782 -164.745 31.186 0.46 16.95 ? 369 ARG A CA 1 ATOM 2267 C C . ARG A 1 298 ? 22.364 -163.606 32.113 1.00 17.54 ? 369 ARG A C 1 ATOM 2268 O O . ARG A 1 298 ? 21.461 -163.747 32.937 1.00 19.05 ? 369 ARG A O 1 ATOM 2269 C CB A ARG A 1 298 ? 21.746 -165.877 31.222 0.54 16.83 ? 369 ARG A CB 1 ATOM 2270 C CB B ARG A 1 298 ? 21.750 -165.875 31.186 0.46 16.78 ? 369 ARG A CB 1 ATOM 2271 C CG A ARG A 1 298 ? 20.457 -165.562 30.484 0.54 18.40 ? 369 ARG A CG 1 ATOM 2272 C CG B ARG A 1 298 ? 20.550 -165.612 30.295 0.46 18.32 ? 369 ARG A CG 1 ATOM 2273 C CD A ARG A 1 298 ? 19.440 -166.683 30.644 0.54 22.52 ? 369 ARG A CD 1 ATOM 2274 C CD B ARG A 1 298 ? 19.658 -166.838 30.184 0.46 22.27 ? 369 ARG A CD 1 ATOM 2275 N NE A ARG A 1 298 ? 19.898 -167.940 30.048 0.54 22.38 ? 369 ARG A NE 1 ATOM 2276 N NE B ARG A 1 298 ? 20.328 -167.953 29.515 0.46 23.02 ? 369 ARG A NE 1 ATOM 2277 C CZ A ARG A 1 298 ? 19.771 -169.146 30.603 0.54 23.64 ? 369 ARG A CZ 1 ATOM 2278 C CZ B ARG A 1 298 ? 20.378 -168.124 28.196 0.46 23.16 ? 369 ARG A CZ 1 ATOM 2279 N NH1 A ARG A 1 298 ? 19.200 -169.301 31.791 0.54 24.36 ? 369 ARG A NH1 1 ATOM 2280 N NH1 B ARG A 1 298 ? 19.804 -167.251 27.378 0.46 21.34 ? 369 ARG A NH1 1 ATOM 2281 N NH2 A ARG A 1 298 ? 20.226 -170.213 29.960 0.54 25.23 ? 369 ARG A NH2 1 ATOM 2282 N NH2 B ARG A 1 298 ? 21.011 -169.174 27.690 0.46 28.50 ? 369 ARG A NH2 1 ATOM 2283 N N . ASN A 1 299 ? 23.042 -162.473 31.961 1.00 17.91 ? 370 ASN A N 1 ATOM 2284 C CA . ASN A 1 299 ? 22.867 -161.335 32.847 1.00 21.65 ? 370 ASN A CA 1 ATOM 2285 C C . ASN A 1 299 ? 21.882 -160.295 32.355 1.00 22.33 ? 370 ASN A C 1 ATOM 2286 O O . ASN A 1 299 ? 21.517 -159.393 33.114 1.00 18.01 ? 370 ASN A O 1 ATOM 2287 C CB . ASN A 1 299 ? 24.216 -160.653 33.071 1.00 19.49 ? 370 ASN A CB 1 ATOM 2288 C CG . ASN A 1 299 ? 25.291 -161.623 33.495 1.00 17.74 ? 370 ASN A CG 1 ATOM 2289 O OD1 . ASN A 1 299 ? 25.022 -162.593 34.204 1.00 19.88 ? 370 ASN A OD1 1 ATOM 2290 N ND2 . ASN A 1 299 ? 26.518 -161.370 33.061 1.00 18.57 ? 370 ASN A ND2 1 ATOM 2291 N N . TYR A 1 300 ? 21.459 -160.401 31.097 1.00 17.21 ? 371 TYR A N 1 ATOM 2292 C CA . TYR A 1 300 ? 20.712 -159.312 30.483 1.00 14.84 ? 371 TYR A CA 1 ATOM 2293 C C . TYR A 1 300 ? 19.302 -159.729 30.173 1.00 18.23 ? 371 TYR A C 1 ATOM 2294 O O . TYR A 1 300 ? 19.057 -160.870 29.797 1.00 19.61 ? 371 TYR A O 1 ATOM 2295 C CB . TYR A 1 300 ? 21.428 -158.852 29.218 1.00 11.46 ? 371 TYR A CB 1 ATOM 2296 C CG . TYR A 1 300 ? 22.895 -158.656 29.474 1.00 12.96 ? 371 TYR A CG 1 ATOM 2297 C CD1 . TYR A 1 300 ? 23.358 -157.496 30.069 1.00 14.22 ? 371 TYR A CD1 1 ATOM 2298 C CD2 . TYR A 1 300 ? 23.814 -159.646 29.160 1.00 17.03 ? 371 TYR A CD2 1 ATOM 2299 C CE1 . TYR A 1 300 ? 24.694 -157.316 30.328 1.00 21.07 ? 371 TYR A CE1 1 ATOM 2300 C CE2 . TYR A 1 300 ? 25.159 -159.473 29.412 1.00 12.61 ? 371 TYR A CE2 1 ATOM 2301 C CZ . TYR A 1 300 ? 25.594 -158.303 29.998 1.00 19.05 ? 371 TYR A CZ 1 ATOM 2302 O OH . TYR A 1 300 ? 26.932 -158.113 30.260 1.00 19.68 ? 371 TYR A OH 1 ATOM 2303 N N . GLY A 1 301 ? 18.359 -158.818 30.351 1.00 16.13 ? 372 GLY A N 1 ATOM 2304 C CA . GLY A 1 301 ? 17.013 -159.149 29.952 1.00 18.21 ? 372 GLY A CA 1 ATOM 2305 C C . GLY A 1 301 ? 16.108 -157.962 29.804 1.00 15.91 ? 372 GLY A C 1 ATOM 2306 O O . GLY A 1 301 ? 16.503 -156.828 30.070 1.00 16.56 ? 372 GLY A O 1 ATOM 2307 N N . PHE A 1 302 ? 14.886 -158.216 29.354 1.00 10.61 ? 373 PHE A N 1 ATOM 2308 C CA . PHE A 1 302 ? 13.885 -157.163 29.386 1.00 13.07 ? 373 PHE A CA 1 ATOM 2309 C C . PHE A 1 302 ? 12.470 -157.683 29.514 1.00 11.64 ? 373 PHE A C 1 ATOM 2310 O O . PHE A 1 302 ? 12.138 -158.790 29.067 1.00 18.03 ? 373 PHE A O 1 ATOM 2311 C CB . PHE A 1 302 ? 13.986 -156.258 28.146 1.00 9.91 ? 373 PHE A CB 1 ATOM 2312 C CG . PHE A 1 302 ? 13.927 -156.985 26.832 1.00 13.03 ? 373 PHE A CG 1 ATOM 2313 C CD1 . PHE A 1 302 ? 12.712 -157.325 26.255 1.00 15.38 ? 373 PHE A CD1 1 ATOM 2314 C CD2 . PHE A 1 302 ? 15.093 -157.293 26.153 1.00 13.75 ? 373 PHE A CD2 1 ATOM 2315 C CE1 . PHE A 1 302 ? 12.668 -157.981 25.034 1.00 15.76 ? 373 PHE A CE1 1 ATOM 2316 C CE2 . PHE A 1 302 ? 15.055 -157.946 24.938 1.00 13.06 ? 373 PHE A CE2 1 ATOM 2317 C CZ . PHE A 1 302 ? 13.842 -158.290 24.376 1.00 15.89 ? 373 PHE A CZ 1 ATOM 2318 N N . TYR A 1 303 ? 11.655 -156.863 30.167 1.00 12.44 ? 374 TYR A N 1 ATOM 2319 C CA . TYR A 1 303 ? 10.223 -157.060 30.212 1.00 11.62 ? 374 TYR A CA 1 ATOM 2320 C C . TYR A 1 303 ? 9.622 -156.440 28.965 1.00 21.68 ? 374 TYR A C 1 ATOM 2321 O O . TYR A 1 303 ? 10.022 -155.336 28.557 1.00 16.95 ? 374 TYR A O 1 ATOM 2322 C CB . TYR A 1 303 ? 9.618 -156.429 31.467 1.00 15.22 ? 374 TYR A CB 1 ATOM 2323 C CG . TYR A 1 303 ? 8.105 -156.372 31.458 1.00 14.95 ? 374 TYR A CG 1 ATOM 2324 C CD1 . TYR A 1 303 ? 7.347 -157.420 31.963 1.00 19.45 ? 374 TYR A CD1 1 ATOM 2325 C CD2 . TYR A 1 303 ? 7.437 -155.266 30.951 1.00 18.79 ? 374 TYR A CD2 1 ATOM 2326 C CE1 . TYR A 1 303 ? 5.966 -157.369 31.961 1.00 18.00 ? 374 TYR A CE1 1 ATOM 2327 C CE2 . TYR A 1 303 ? 6.056 -155.207 30.940 1.00 20.41 ? 374 TYR A CE2 1 ATOM 2328 C CZ . TYR A 1 303 ? 5.325 -156.262 31.448 1.00 24.08 ? 374 TYR A CZ 1 ATOM 2329 O OH . TYR A 1 303 ? 3.949 -156.213 31.446 1.00 30.62 ? 374 TYR A OH 1 ATOM 2330 N N . TYR A 1 304 ? 8.681 -157.161 28.359 1.00 14.64 ? 375 TYR A N 1 ATOM 2331 C CA . TYR A 1 304 ? 7.909 -156.632 27.238 1.00 19.47 ? 375 TYR A CA 1 ATOM 2332 C C . TYR A 1 304 ? 6.498 -157.215 27.216 1.00 24.42 ? 375 TYR A C 1 ATOM 2333 O O . TYR A 1 304 ? 6.238 -158.268 27.800 1.00 24.46 ? 375 TYR A O 1 ATOM 2334 C CB . TYR A 1 304 ? 8.615 -156.916 25.908 1.00 16.49 ? 375 TYR A CB 1 ATOM 2335 C CG . TYR A 1 304 ? 8.634 -158.372 25.505 1.00 20.07 ? 375 TYR A CG 1 ATOM 2336 C CD1 . TYR A 1 304 ? 9.565 -159.249 26.044 1.00 19.30 ? 375 TYR A CD1 1 ATOM 2337 C CD2 . TYR A 1 304 ? 7.730 -158.865 24.572 1.00 21.76 ? 375 TYR A CD2 1 ATOM 2338 C CE1 . TYR A 1 304 ? 9.589 -160.578 25.675 1.00 21.33 ? 375 TYR A CE1 1 ATOM 2339 C CE2 . TYR A 1 304 ? 7.746 -160.194 24.196 1.00 23.48 ? 375 TYR A CE2 1 ATOM 2340 C CZ . TYR A 1 304 ? 8.678 -161.046 24.749 1.00 24.73 ? 375 TYR A CZ 1 ATOM 2341 O OH . TYR A 1 304 ? 8.698 -162.369 24.378 1.00 28.13 ? 375 TYR A OH 1 ATOM 2342 N N . VAL A 1 305 ? 5.591 -156.510 26.547 1.00 27.42 ? 376 VAL A N 1 ATOM 2343 C CA . VAL A 1 305 ? 4.215 -156.964 26.362 1.00 23.94 ? 376 VAL A CA 1 ATOM 2344 C C . VAL A 1 305 ? 4.065 -157.559 24.968 1.00 23.44 ? 376 VAL A C 1 ATOM 2345 O O . VAL A 1 305 ? 4.318 -156.879 23.973 1.00 25.64 ? 376 VAL A O 1 ATOM 2346 C CB . VAL A 1 305 ? 3.207 -155.810 26.540 1.00 33.63 ? 376 VAL A CB 1 ATOM 2347 C CG1 . VAL A 1 305 ? 1.775 -156.306 26.354 1.00 36.14 ? 376 VAL A CG1 1 ATOM 2348 C CG2 . VAL A 1 305 ? 3.373 -155.164 27.906 1.00 34.89 ? 376 VAL A CG2 1 ATOM 2349 N N . ASP A 1 306 ? 3.656 -158.823 24.893 1.00 31.99 ? 377 ASP A N 1 ATOM 2350 C CA . ASP A 1 306 ? 3.492 -159.490 23.604 1.00 36.48 ? 377 ASP A CA 1 ATOM 2351 C C . ASP A 1 306 ? 2.250 -158.986 22.873 1.00 37.68 ? 377 ASP A C 1 ATOM 2352 O O . ASP A 1 306 ? 1.500 -158.162 23.396 1.00 31.96 ? 377 ASP A O 1 ATOM 2353 C CB . ASP A 1 306 ? 3.425 -161.016 23.780 1.00 39.19 ? 377 ASP A CB 1 ATOM 2354 C CG . ASP A 1 306 ? 2.310 -161.465 24.718 1.00 51.01 ? 377 ASP A CG 1 ATOM 2355 O OD1 . ASP A 1 306 ? 1.285 -160.761 24.844 1.00 52.62 ? 377 ASP A OD1 1 ATOM 2356 O OD2 . ASP A 1 306 ? 2.461 -162.544 25.331 1.00 65.00 ? 377 ASP A OD2 1 ATOM 2357 N N . THR A 1 307 ? 2.038 -159.497 21.665 1.00 42.39 ? 378 THR A N 1 ATOM 2358 C CA . THR A 1 307 ? 0.952 -159.038 20.808 1.00 54.40 ? 378 THR A CA 1 ATOM 2359 C C . THR A 1 307 ? -0.433 -159.247 21.420 1.00 49.00 ? 378 THR A C 1 ATOM 2360 O O . THR A 1 307 ? -1.387 -158.564 21.045 1.00 54.11 ? 378 THR A O 1 ATOM 2361 C CB . THR A 1 307 ? 0.994 -159.752 19.447 1.00 62.80 ? 378 THR A CB 1 ATOM 2362 O OG1 . THR A 1 307 ? 0.951 -161.171 19.648 1.00 54.77 ? 378 THR A OG1 1 ATOM 2363 C CG2 . THR A 1 307 ? 2.265 -159.388 18.694 1.00 55.86 ? 378 THR A CG2 1 ATOM 2364 N N . THR A 1 308 ? -0.542 -160.182 22.360 1.00 45.76 ? 379 THR A N 1 ATOM 2365 C CA . THR A 1 308 ? -1.832 -160.507 22.969 1.00 44.89 ? 379 THR A CA 1 ATOM 2366 C C . THR A 1 308 ? -2.074 -159.718 24.255 1.00 56.70 ? 379 THR A C 1 ATOM 2367 O O . THR A 1 308 ? -3.182 -159.724 24.794 1.00 51.49 ? 379 THR A O 1 ATOM 2368 C CB . THR A 1 308 ? -1.942 -162.011 23.286 1.00 57.08 ? 379 THR A CB 1 ATOM 2369 O OG1 . THR A 1 308 ? -1.151 -162.323 24.439 1.00 56.14 ? 379 THR A OG1 1 ATOM 2370 C CG2 . THR A 1 308 ? -1.476 -162.846 22.103 1.00 56.62 ? 379 THR A CG2 1 ATOM 2371 N N . GLY A 1 309 ? -1.033 -159.050 24.747 1.00 41.17 ? 380 GLY A N 1 ATOM 2372 C CA . GLY A 1 309 ? -1.152 -158.187 25.910 1.00 36.72 ? 380 GLY A CA 1 ATOM 2373 C C . GLY A 1 309 ? -0.634 -158.797 27.200 1.00 41.35 ? 380 GLY A C 1 ATOM 2374 O O . GLY A 1 309 ? -0.830 -158.231 28.277 1.00 38.03 ? 380 GLY A O 1 ATOM 2375 N N . GLU A 1 310 ? 0.028 -159.946 27.095 1.00 34.60 ? 381 GLU A N 1 ATOM 2376 C CA . GLU A 1 310 ? 0.589 -160.615 28.266 1.00 47.83 ? 381 GLU A CA 1 ATOM 2377 C C . GLU A 1 310 ? 2.051 -160.239 28.467 1.00 35.05 ? 381 GLU A C 1 ATOM 2378 O O . GLU A 1 310 ? 2.794 -160.044 27.505 1.00 25.10 ? 381 GLU A O 1 ATOM 2379 C CB . GLU A 1 310 ? 0.448 -162.135 28.137 1.00 41.68 ? 381 GLU A CB 1 ATOM 2380 C CG . GLU A 1 310 ? -0.866 -162.682 28.682 1.00 58.58 ? 381 GLU A CG 1 ATOM 2381 C CD . GLU A 1 310 ? -1.011 -162.476 30.181 1.00 89.32 ? 381 GLU A CD 1 ATOM 2382 O OE1 . GLU A 1 310 ? -1.682 -161.503 30.590 1.00 63.81 ? 381 GLU A OE1 1 ATOM 2383 O OE2 . GLU A 1 310 ? -0.453 -163.286 30.952 1.00 83.34 ? 381 GLU A OE2 1 ATOM 2384 N N . GLY A 1 311 ? 2.453 -160.139 29.729 1.00 27.55 ? 382 GLY A N 1 ATOM 2385 C CA . GLY A 1 311 ? 3.813 -159.777 30.075 1.00 25.17 ? 382 GLY A CA 1 ATOM 2386 C C . GLY A 1 311 ? 4.791 -160.914 29.856 1.00 20.02 ? 382 GLY A C 1 ATOM 2387 O O . GLY A 1 311 ? 4.510 -162.068 30.186 1.00 16.57 ? 382 GLY A O 1 ATOM 2388 N N . LYS A 1 312 ? 5.948 -160.573 29.300 1.00 18.68 ? 383 LYS A N 1 ATOM 2389 C CA . LYS A 1 312 ? 6.998 -161.539 29.023 1.00 17.48 ? 383 LYS A CA 1 ATOM 2390 C C . LYS A 1 312 ? 8.347 -161.002 29.462 1.00 20.41 ? 383 LYS A C 1 ATOM 2391 O O . LYS A 1 312 ? 8.563 -159.787 29.504 1.00 16.59 ? 383 LYS A O 1 ATOM 2392 C CB . LYS A 1 312 ? 7.048 -161.874 27.535 1.00 18.78 ? 383 LYS A CB 1 ATOM 2393 C CG . LYS A 1 312 ? 5.814 -162.560 26.992 1.00 33.13 ? 383 LYS A CG 1 ATOM 2394 C CD . LYS A 1 312 ? 5.861 -164.065 27.223 1.00 33.31 ? 383 LYS A CD 1 ATOM 2395 C CE . LYS A 1 312 ? 4.715 -164.784 26.521 1.00 43.33 ? 383 LYS A CE 1 ATOM 2396 N NZ . LYS A 1 312 ? 4.502 -164.292 25.130 1.00 53.46 ? 383 LYS A NZ 1 ATOM 2397 N N . CYS A 1 313 ? 9.243 -161.931 29.778 1.00 16.60 ? 384 CYS A N 1 ATOM 2398 C CA . CYS A 1 313 ? 10.614 -161.621 30.143 1.00 14.44 ? 384 CYS A CA 1 ATOM 2399 C C . CYS A 1 313 ? 11.563 -162.356 29.208 1.00 19.71 ? 384 CYS A C 1 ATOM 2400 O O . CYS A 1 313 ? 11.537 -163.592 29.129 1.00 24.88 ? 384 CYS A O 1 ATOM 2401 C CB . CYS A 1 313 ? 10.888 -162.011 31.599 1.00 15.91 ? 384 CYS A CB 1 ATOM 2402 S SG . CYS A 1 313 ? 12.480 -161.450 32.239 1.00 27.06 ? 384 CYS A SG 1 ATOM 2403 N N . ALA A 1 314 ? 12.381 -161.591 28.488 1.00 14.95 ? 385 ALA A N 1 ATOM 2404 C CA . ALA A 1 314 ? 13.410 -162.161 27.622 1.00 13.77 ? 385 ALA A CA 1 ATOM 2405 C C . ALA A 1 314 ? 14.765 -162.047 28.301 1.00 17.55 ? 385 ALA A C 1 ATOM 2406 O O . ALA A 1 314 ? 15.145 -160.963 28.751 1.00 19.90 ? 385 ALA A O 1 ATOM 2407 C CB . ALA A 1 314 ? 13.432 -161.466 26.281 1.00 17.02 ? 385 ALA A CB 1 ATOM 2408 N N . LEU A 1 315 ? 15.475 -163.173 28.362 1.00 17.18 ? 386 LEU A N 1 ATOM 2409 C CA . LEU A 1 315 ? 16.759 -163.279 29.050 1.00 16.99 ? 386 LEU A CA 1 ATOM 2410 C C . LEU A 1 315 ? 17.858 -163.778 28.116 1.00 17.88 ? 386 LEU A C 1 ATOM 2411 O O . LEU A 1 315 ? 17.670 -164.751 27.380 1.00 21.62 ? 386 LEU A O 1 ATOM 2412 C CB . LEU A 1 315 ? 16.651 -164.227 30.243 1.00 16.79 ? 386 LEU A CB 1 ATOM 2413 C CG . LEU A 1 315 ? 15.600 -163.915 31.305 1.00 22.86 ? 386 LEU A CG 1 ATOM 2414 C CD1 . LEU A 1 315 ? 15.405 -165.122 32.213 1.00 21.28 ? 386 LEU A CD1 1 ATOM 2415 C CD2 . LEU A 1 315 ? 16.008 -162.700 32.112 1.00 22.77 ? 386 LEU A CD2 1 ATOM 2416 N N . SER A 1 316 ? 19.015 -163.124 28.183 1.00 16.47 ? 387 SER A N 1 ATOM 2417 C CA . SER A 1 316 ? 20.135 -163.427 27.304 1.00 15.97 ? 387 SER A CA 1 ATOM 2418 C C . SER A 1 316 ? 21.482 -163.164 27.971 1.00 17.13 ? 387 SER A C 1 ATOM 2419 O O . SER A 1 316 ? 21.596 -162.362 28.918 1.00 18.86 ? 387 SER A O 1 ATOM 2420 C CB . SER A 1 316 ? 20.033 -162.606 26.016 1.00 20.17 ? 387 SER A CB 1 ATOM 2421 O OG . SER A 1 316 ? 21.127 -162.864 25.155 1.00 17.92 ? 387 SER A OG 1 ATOM 2422 N N . ASP A 1 317 ? 22.494 -163.859 27.455 1.00 15.33 ? 388 ASP A N 1 ATOM 2423 C CA . ASP A 1 317 ? 23.878 -163.681 27.877 1.00 20.44 ? 388 ASP A CA 1 ATOM 2424 C C . ASP A 1 317 ? 24.669 -162.892 26.836 1.00 17.53 ? 388 ASP A C 1 ATOM 2425 O O . ASP A 1 317 ? 25.874 -162.685 26.982 1.00 20.71 ? 388 ASP A O 1 ATOM 2426 C CB . ASP A 1 317 ? 24.543 -165.040 28.124 1.00 23.24 ? 388 ASP A CB 1 ATOM 2427 C CG . ASP A 1 317 ? 24.643 -165.884 26.865 1.00 43.12 ? 388 ASP A CG 1 ATOM 2428 O OD1 . ASP A 1 317 ? 23.941 -165.582 25.876 1.00 39.36 ? 388 ASP A OD1 1 ATOM 2429 O OD2 . ASP A 1 317 ? 25.421 -166.862 26.868 1.00 40.68 ? 388 ASP A OD2 1 ATOM 2430 N N . GLN A 1 318 ? 23.984 -162.456 25.783 1.00 16.78 ? 389 GLN A N 1 ATOM 2431 C CA . GLN A 1 318 ? 24.599 -161.623 24.759 1.00 22.57 ? 389 GLN A CA 1 ATOM 2432 C C . GLN A 1 318 ? 24.695 -160.181 25.231 1.00 16.39 ? 389 GLN A C 1 ATOM 2433 O O . GLN A 1 318 ? 23.678 -159.547 25.517 1.00 18.28 ? 389 GLN A O 1 ATOM 2434 C CB . GLN A 1 318 ? 23.798 -161.693 23.457 1.00 22.53 ? 389 GLN A CB 1 ATOM 2435 C CG . GLN A 1 318 ? 23.761 -163.072 22.822 1.00 31.98 ? 389 GLN A CG 1 ATOM 2436 C CD . GLN A 1 318 ? 25.097 -163.478 22.231 1.00 44.01 ? 389 GLN A CD 1 ATOM 2437 O OE1 . GLN A 1 318 ? 25.691 -164.477 22.637 1.00 60.19 ? 389 GLN A OE1 1 ATOM 2438 N NE2 . GLN A 1 318 ? 25.573 -162.706 21.261 1.00 54.93 ? 389 GLN A NE2 1 ATOM 2439 N N . VAL A 1 319 ? 25.915 -159.664 25.312 1.00 25.71 ? 390 VAL A N 1 ATOM 2440 C CA . VAL A 1 319 ? 26.118 -158.273 25.695 1.00 22.55 ? 390 VAL A CA 1 ATOM 2441 C C . VAL A 1 319 ? 25.416 -157.372 24.683 1.00 22.36 ? 390 VAL A C 1 ATOM 2442 O O . VAL A 1 319 ? 25.670 -157.471 23.483 1.00 24.86 ? 390 VAL A O 1 ATOM 2443 C CB . VAL A 1 319 ? 27.614 -157.914 25.771 1.00 23.42 ? 390 VAL A CB 1 ATOM 2444 C CG1 . VAL A 1 319 ? 27.807 -156.411 25.990 1.00 21.78 ? 390 VAL A CG1 1 ATOM 2445 C CG2 . VAL A 1 319 ? 28.287 -158.701 26.888 1.00 28.62 ? 390 VAL A CG2 1 ATOM 2446 N N . PRO A 1 320 ? 24.523 -156.493 25.158 1.00 22.18 ? 391 PRO A N 1 ATOM 2447 C CA . PRO A 1 320 ? 23.802 -155.646 24.203 1.00 22.23 ? 391 PRO A CA 1 ATOM 2448 C C . PRO A 1 320 ? 24.711 -154.611 23.555 1.00 20.71 ? 391 PRO A C 1 ATOM 2449 O O . PRO A 1 320 ? 25.537 -154.018 24.248 1.00 27.92 ? 391 PRO A O 1 ATOM 2450 C CB . PRO A 1 320 ? 22.734 -154.973 25.066 1.00 19.49 ? 391 PRO A CB 1 ATOM 2451 C CG . PRO A 1 320 ? 23.294 -154.979 26.441 1.00 20.49 ? 391 PRO A CG 1 ATOM 2452 C CD . PRO A 1 320 ? 24.136 -156.210 26.552 1.00 18.95 ? 391 PRO A CD 1 ATOM 2453 N N . ASP A 1 321 ? 24.572 -154.414 22.246 1.00 21.48 ? 392 ASP A N 1 ATOM 2454 C CA . ASP A 1 321 ? 25.290 -153.348 21.555 1.00 22.34 ? 392 ASP A CA 1 ATOM 2455 C C . ASP A 1 321 ? 24.336 -152.510 20.712 1.00 20.98 ? 392 ASP A C 1 ATOM 2456 O O . ASP A 1 321 ? 24.767 -151.623 19.971 1.00 21.66 ? 392 ASP A O 1 ATOM 2457 C CB . ASP A 1 321 ? 26.421 -153.914 20.685 1.00 29.07 ? 392 ASP A CB 1 ATOM 2458 C CG . ASP A 1 321 ? 25.929 -154.887 19.624 1.00 34.31 ? 392 ASP A CG 1 ATOM 2459 O OD1 . ASP A 1 321 ? 24.738 -154.843 19.253 1.00 32.84 ? 392 ASP A OD1 1 ATOM 2460 O OD2 . ASP A 1 321 ? 26.750 -155.698 19.146 1.00 43.05 ? 392 ASP A OD2 1 ATOM 2461 N N . CYS A 1 322 ? 23.041 -152.801 20.805 1.00 20.80 ? 393 CYS A N 1 ATOM 2462 C CA . CYS A 1 322 ? 22.044 -151.887 20.265 1.00 20.69 ? 393 CYS A CA 1 ATOM 2463 C C . CYS A 1 322 ? 20.732 -152.001 21.026 1.00 19.37 ? 393 CYS A C 1 ATOM 2464 O O . CYS A 1 322 ? 20.580 -152.857 21.905 1.00 20.96 ? 393 CYS A O 1 ATOM 2465 C CB . CYS A 1 322 ? 21.819 -152.153 18.775 1.00 26.23 ? 393 CYS A CB 1 ATOM 2466 S SG . CYS A 1 322 ? 21.159 -153.786 18.423 1.00 25.62 ? 393 CYS A SG 1 ATOM 2467 N N . LEU A 1 323 ? 19.792 -151.127 20.679 1.00 17.30 ? 394 LEU A N 1 ATOM 2468 C CA . LEU A 1 323 ? 18.497 -151.065 21.344 1.00 20.51 ? 394 LEU A CA 1 ATOM 2469 C C . LEU A 1 323 ? 17.365 -151.070 20.330 1.00 18.97 ? 394 LEU A C 1 ATOM 2470 O O . LEU A 1 323 ? 17.507 -150.533 19.230 1.00 19.18 ? 394 LEU A O 1 ATOM 2471 C CB . LEU A 1 323 ? 18.396 -149.806 22.210 1.00 19.09 ? 394 LEU A CB 1 ATOM 2472 C CG . LEU A 1 323 ? 19.478 -149.583 23.269 1.00 18.37 ? 394 LEU A CG 1 ATOM 2473 C CD1 . LEU A 1 323 ? 19.302 -148.217 23.905 1.00 19.09 ? 394 LEU A CD1 1 ATOM 2474 C CD2 . LEU A 1 323 ? 19.446 -150.670 24.328 1.00 18.42 ? 394 LEU A CD2 1 ATOM 2475 N N . VAL A 1 324 ? 16.246 -151.681 20.708 1.00 17.99 ? 395 VAL A N 1 ATOM 2476 C CA . VAL A 1 324 ? 15.010 -151.586 19.933 1.00 17.40 ? 395 VAL A CA 1 ATOM 2477 C C . VAL A 1 324 ? 13.989 -150.807 20.748 1.00 20.95 ? 395 VAL A C 1 ATOM 2478 O O . VAL A 1 324 ? 13.667 -151.186 21.871 1.00 17.99 ? 395 VAL A O 1 ATOM 2479 C CB . VAL A 1 324 ? 14.440 -152.974 19.570 1.00 21.23 ? 395 VAL A CB 1 ATOM 2480 C CG1 . VAL A 1 324 ? 13.045 -152.849 18.953 1.00 25.53 ? 395 VAL A CG1 1 ATOM 2481 C CG2 . VAL A 1 324 ? 15.375 -153.698 18.614 1.00 22.98 ? 395 VAL A CG2 1 ATOM 2482 N N . SER A 1 325 ? 13.477 -149.719 20.188 1.00 18.15 ? 396 SER A N 1 ATOM 2483 C CA . SER A 1 325 ? 12.536 -148.883 20.919 1.00 21.59 ? 396 SER A CA 1 ATOM 2484 C C . SER A 1 325 ? 11.193 -149.589 21.078 1.00 15.74 ? 396 SER A C 1 ATOM 2485 O O . SER A 1 325 ? 10.646 -150.143 20.125 1.00 21.15 ? 396 SER A O 1 ATOM 2486 C CB . SER A 1 325 ? 12.356 -147.533 20.217 1.00 19.92 ? 396 SER A CB 1 ATOM 2487 O OG . SER A 1 325 ? 12.121 -147.698 18.833 1.00 33.02 ? 396 SER A OG 1 ATOM 2488 N N . ASP A 1 326 ? 10.686 -149.573 22.306 1.00 20.12 ? 397 ASP A N 1 ATOM 2489 C CA . ASP A 1 326 ? 9.397 -150.164 22.641 1.00 18.13 ? 397 ASP A CA 1 ATOM 2490 C C . ASP A 1 326 ? 8.949 -149.563 23.968 1.00 23.72 ? 397 ASP A C 1 ATOM 2491 O O . ASP A 1 326 ? 9.470 -149.916 25.024 1.00 23.00 ? 397 ASP A O 1 ATOM 2492 C CB . ASP A 1 326 ? 9.501 -151.690 22.723 1.00 21.59 ? 397 ASP A CB 1 ATOM 2493 C CG . ASP A 1 326 ? 8.192 -152.349 23.120 1.00 34.82 ? 397 ASP A CG 1 ATOM 2494 O OD1 . ASP A 1 326 ? 7.132 -151.698 23.004 1.00 40.51 ? 397 ASP A OD1 1 ATOM 2495 O OD2 . ASP A 1 326 ? 8.226 -153.526 23.540 1.00 28.88 ? 397 ASP A OD2 1 ATOM 2496 N N . SER A 1 327 ? 7.986 -148.650 23.904 1.00 22.16 ? 398 SER A N 1 ATOM 2497 C CA . SER A 1 327 ? 7.664 -147.791 25.040 1.00 28.95 ? 398 SER A CA 1 ATOM 2498 C C . SER A 1 327 ? 7.213 -148.556 26.287 1.00 21.53 ? 398 SER A C 1 ATOM 2499 O O . SER A 1 327 ? 7.417 -148.089 27.408 1.00 31.72 ? 398 SER A O 1 ATOM 2500 C CB . SER A 1 327 ? 6.581 -146.788 24.637 1.00 30.34 ? 398 SER A CB 1 ATOM 2501 O OG . SER A 1 327 ? 5.386 -147.452 24.267 1.00 35.93 ? 398 SER A OG 1 ATOM 2502 N N . ALA A 1 328 ? 6.610 -149.725 26.096 1.00 21.68 ? 399 ALA A N 1 ATOM 2503 C CA . ALA A 1 328 ? 6.112 -150.518 27.216 1.00 24.71 ? 399 ALA A CA 1 ATOM 2504 C C . ALA A 1 328 ? 7.182 -151.449 27.781 1.00 23.00 ? 399 ALA A C 1 ATOM 2505 O O . ALA A 1 328 ? 6.992 -152.058 28.834 1.00 22.08 ? 399 ALA A O 1 ATOM 2506 C CB . ALA A 1 328 ? 4.902 -151.321 26.790 1.00 29.68 ? 399 ALA A CB 1 ATOM 2507 N N . ALA A 1 329 ? 8.304 -151.562 27.080 1.00 13.67 ? 400 ALA A N 1 ATOM 2508 C CA . ALA A 1 329 ? 9.368 -152.464 27.497 1.00 12.76 ? 400 ALA A CA 1 ATOM 2509 C C . ALA A 1 329 ? 10.279 -151.838 28.544 1.00 22.44 ? 400 ALA A C 1 ATOM 2510 O O . ALA A 1 329 ? 10.391 -150.613 28.640 1.00 15.87 ? 400 ALA A O 1 ATOM 2511 C CB . ALA A 1 329 ? 10.188 -152.891 26.300 1.00 10.32 ? 400 ALA A CB 1 ATOM 2512 N N . VAL A 1 330 ? 10.931 -152.693 29.326 1.00 13.45 ? 401 VAL A N 1 ATOM 2513 C CA . VAL A 1 330 ? 11.976 -152.239 30.246 1.00 10.90 ? 401 VAL A CA 1 ATOM 2514 C C . VAL A 1 330 ? 13.125 -153.239 30.261 1.00 14.60 ? 401 VAL A C 1 ATOM 2515 O O . VAL A 1 330 ? 12.909 -154.439 30.444 1.00 17.44 ? 401 VAL A O 1 ATOM 2516 C CB . VAL A 1 330 ? 11.456 -152.048 31.692 1.00 13.73 ? 401 VAL A CB 1 ATOM 2517 C CG1 . VAL A 1 330 ? 12.549 -151.455 32.577 1.00 16.63 ? 401 VAL A CG1 1 ATOM 2518 C CG2 . VAL A 1 330 ? 10.225 -151.154 31.712 1.00 18.10 ? 401 VAL A CG2 1 ATOM 2519 N N . SER A 1 331 ? 14.343 -152.733 30.073 1.00 10.33 ? 402 SER A N 1 ATOM 2520 C CA . SER A 1 331 ? 15.538 -153.572 30.031 1.00 15.72 ? 402 SER A CA 1 ATOM 2521 C C . SER A 1 331 ? 16.304 -153.556 31.352 1.00 18.20 ? 402 SER A C 1 ATOM 2522 O O . SER A 1 331 ? 16.634 -152.495 31.883 1.00 16.96 ? 402 SER A O 1 ATOM 2523 C CB . SER A 1 331 ? 16.460 -153.125 28.898 1.00 11.11 ? 402 SER A CB 1 ATOM 2524 O OG . SER A 1 331 ? 15.891 -153.415 27.635 1.00 15.27 ? 402 SER A OG 1 ATOM 2525 N N . TYR A 1 332 ? 16.588 -154.750 31.861 1.00 14.98 ? 403 TYR A N 1 ATOM 2526 C CA . TYR A 1 332 ? 17.280 -154.929 33.128 1.00 13.16 ? 403 TYR A CA 1 ATOM 2527 C C . TYR A 1 332 ? 18.581 -155.709 32.969 1.00 15.09 ? 403 TYR A C 1 ATOM 2528 O O . TYR A 1 332 ? 18.773 -156.447 31.988 1.00 15.20 ? 403 TYR A O 1 ATOM 2529 C CB . TYR A 1 332 ? 16.390 -155.672 34.126 1.00 18.34 ? 403 TYR A CB 1 ATOM 2530 C CG . TYR A 1 332 ? 15.026 -155.070 34.357 1.00 11.56 ? 403 TYR A CG 1 ATOM 2531 C CD1 . TYR A 1 332 ? 14.862 -153.956 35.170 1.00 13.87 ? 403 TYR A CD1 1 ATOM 2532 C CD2 . TYR A 1 332 ? 13.897 -155.640 33.792 1.00 14.19 ? 403 TYR A CD2 1 ATOM 2533 C CE1 . TYR A 1 332 ? 13.613 -153.416 35.393 1.00 15.14 ? 403 TYR A CE1 1 ATOM 2534 C CE2 . TYR A 1 332 ? 12.645 -155.107 34.009 1.00 16.92 ? 403 TYR A CE2 1 ATOM 2535 C CZ . TYR A 1 332 ? 12.509 -153.997 34.811 1.00 11.03 ? 403 TYR A CZ 1 ATOM 2536 O OH . TYR A 1 332 ? 11.262 -153.462 35.033 1.00 17.32 ? 403 TYR A OH 1 ATOM 2537 N N . THR A 1 333 ? 19.458 -155.549 33.959 1.00 13.16 ? 404 THR A N 1 ATOM 2538 C CA . THR A 1 333 ? 20.636 -156.396 34.110 1.00 12.93 ? 404 THR A CA 1 ATOM 2539 C C . THR A 1 333 ? 20.665 -156.973 35.520 1.00 15.73 ? 404 THR A C 1 ATOM 2540 O O . THR A 1 333 ? 19.994 -156.472 36.423 1.00 15.63 ? 404 THR A O 1 ATOM 2541 C CB . THR A 1 333 ? 21.949 -155.631 33.846 1.00 16.29 ? 404 THR A CB 1 ATOM 2542 O OG1 . THR A 1 333 ? 22.222 -154.740 34.935 1.00 18.19 ? 404 THR A OG1 1 ATOM 2543 C CG2 . THR A 1 333 ? 21.866 -154.849 32.542 1.00 16.43 ? 404 THR A CG2 1 ATOM 2544 N N . ALA A 1 334 ? 21.446 -158.031 35.701 1.00 18.08 ? 405 ALA A N 1 ATOM 2545 C CA . ALA A 1 334 ? 21.591 -158.668 37.003 1.00 17.14 ? 405 ALA A CA 1 ATOM 2546 C C . ALA A 1 334 ? 22.154 -157.701 38.045 1.00 19.65 ? 405 ALA A C 1 ATOM 2547 O O . ALA A 1 334 ? 21.907 -157.853 39.241 1.00 16.60 ? 405 ALA A O 1 ATOM 2548 C CB . ALA A 1 334 ? 22.486 -159.890 36.885 1.00 13.80 ? 405 ALA A CB 1 ATOM 2549 N N . ALA A 1 335 ? 22.905 -156.706 37.582 1.00 14.97 ? 406 ALA A N 1 ATOM 2550 C CA . ALA A 1 335 ? 23.597 -155.783 38.477 1.00 15.65 ? 406 ALA A CA 1 ATOM 2551 C C . ALA A 1 335 ? 22.736 -154.592 38.895 1.00 17.21 ? 406 ALA A C 1 ATOM 2552 O O . ALA A 1 335 ? 22.912 -154.047 39.984 1.00 16.54 ? 406 ALA A O 1 ATOM 2553 C CB . ALA A 1 335 ? 24.867 -155.287 37.816 1.00 16.79 ? 406 ALA A CB 1 ATOM 2554 N N . GLY A 1 336 ? 21.806 -154.195 38.033 1.00 17.60 ? 407 GLY A N 1 ATOM 2555 C CA . GLY A 1 336 ? 21.099 -152.938 38.205 1.00 10.97 ? 407 GLY A CA 1 ATOM 2556 C C . GLY A 1 336 ? 19.837 -152.988 39.042 1.00 14.28 ? 407 GLY A C 1 ATOM 2557 O O . GLY A 1 336 ? 19.399 -154.049 39.489 1.00 11.01 ? 407 GLY A O 1 ATOM 2558 N N . SER A 1 337 ? 19.251 -151.812 39.245 1.00 12.19 ? 408 SER A N 1 ATOM 2559 C CA . SER A 1 337 ? 18.052 -151.658 40.059 1.00 11.23 ? 408 SER A CA 1 ATOM 2560 C C . SER A 1 337 ? 16.781 -151.876 39.251 1.00 11.48 ? 408 SER A C 1 ATOM 2561 O O . SER A 1 337 ? 16.810 -151.927 38.019 1.00 14.73 ? 408 SER A O 1 ATOM 2562 C CB . SER A 1 337 ? 18.017 -150.264 40.683 1.00 21.14 ? 408 SER A CB 1 ATOM 2563 O OG . SER A 1 337 ? 17.908 -149.273 39.676 1.00 22.75 ? 408 SER A OG 1 ATOM 2564 N N . LEU A 1 338 ? 15.665 -151.991 39.960 1.00 12.08 ? 409 LEU A N 1 ATOM 2565 C CA . LEU A 1 338 ? 14.357 -152.105 39.333 1.00 21.55 ? 409 LEU A CA 1 ATOM 2566 C C . LEU A 1 338 ? 13.935 -150.760 38.765 1.00 23.25 ? 409 LEU A C 1 ATOM 2567 O O . LEU A 1 338 ? 13.329 -150.682 37.697 1.00 20.15 ? 409 LEU A O 1 ATOM 2568 C CB . LEU A 1 338 ? 13.316 -152.594 40.342 1.00 14.60 ? 409 LEU A CB 1 ATOM 2569 C CG . LEU A 1 338 ? 11.850 -152.554 39.896 1.00 21.07 ? 409 LEU A CG 1 ATOM 2570 C CD1 . LEU A 1 338 ? 11.614 -153.532 38.763 1.00 18.54 ? 409 LEU A CD1 1 ATOM 2571 C CD2 . LEU A 1 338 ? 10.925 -152.848 41.064 1.00 26.01 ? 409 LEU A CD2 1 ATOM 2572 N N . SER A 1 339 ? 14.249 -149.701 39.500 1.00 24.23 ? 410 SER A N 1 ATOM 2573 C CA . SER A 1 339 ? 13.815 -148.369 39.118 1.00 21.22 ? 410 SER A CA 1 ATOM 2574 C C . SER A 1 339 ? 14.633 -147.819 37.962 1.00 14.20 ? 410 SER A C 1 ATOM 2575 O O . SER A 1 339 ? 15.818 -148.115 37.811 1.00 14.72 ? 410 SER A O 1 ATOM 2576 C CB . SER A 1 339 ? 13.896 -147.413 40.309 1.00 29.42 ? 410 SER A CB 1 ATOM 2577 O OG . SER A 1 339 ? 13.515 -146.104 39.925 1.00 30.91 ? 410 SER A OG 1 ATOM 2578 N N . GLU A 1 340 ? 13.958 -147.019 37.149 1.00 21.96 ? 411 GLU A N 1 ATOM 2579 C CA A GLU A 1 340 ? 14.614 -146.371 36.023 0.49 24.21 ? 411 GLU A CA 1 ATOM 2580 C CA B GLU A 1 340 ? 14.540 -146.321 36.005 0.51 24.24 ? 411 GLU A CA 1 ATOM 2581 C C . GLU A 1 340 ? 15.202 -145.017 36.426 1.00 27.31 ? 411 GLU A C 1 ATOM 2582 O O . GLU A 1 340 ? 16.042 -144.470 35.713 1.00 27.44 ? 411 GLU A O 1 ATOM 2583 C CB A GLU A 1 340 ? 13.630 -146.216 34.864 0.49 27.52 ? 411 GLU A CB 1 ATOM 2584 C CB B GLU A 1 340 ? 13.462 -146.014 34.946 0.51 27.57 ? 411 GLU A CB 1 ATOM 2585 C CG A GLU A 1 340 ? 12.904 -147.520 34.521 0.49 27.56 ? 411 GLU A CG 1 ATOM 2586 C CG B GLU A 1 340 ? 12.064 -145.674 35.520 0.51 29.09 ? 411 GLU A CG 1 ATOM 2587 C CD A GLU A 1 340 ? 11.589 -147.691 35.259 0.49 36.39 ? 411 GLU A CD 1 ATOM 2588 C CD B GLU A 1 340 ? 11.381 -144.494 34.848 0.51 40.28 ? 411 GLU A CD 1 ATOM 2589 O OE1 A GLU A 1 340 ? 10.759 -148.518 34.812 0.49 19.15 ? 411 GLU A OE1 1 ATOM 2590 O OE1 B GLU A 1 340 ? 11.723 -144.160 33.694 0.51 46.17 ? 411 GLU A OE1 1 ATOM 2591 O OE2 A GLU A 1 340 ? 11.388 -147.012 36.288 0.49 26.82 ? 411 GLU A OE2 1 ATOM 2592 O OE2 B GLU A 1 340 ? 10.491 -143.891 35.487 0.51 36.22 ? 411 GLU A OE2 1 ATOM 2593 N N . GLU A 1 341 ? 14.792 -144.505 37.584 1.00 22.72 ? 412 GLU A N 1 ATOM 2594 C CA . GLU A 1 341 ? 15.238 -143.192 38.043 1.00 26.55 ? 412 GLU A CA 1 ATOM 2595 C C . GLU A 1 341 ? 16.525 -143.248 38.862 1.00 28.28 ? 412 GLU A C 1 ATOM 2596 O O . GLU A 1 341 ? 16.742 -144.171 39.647 1.00 26.81 ? 412 GLU A O 1 ATOM 2597 C CB . GLU A 1 341 ? 14.133 -142.527 38.865 1.00 35.89 ? 412 GLU A CB 1 ATOM 2598 C CG . GLU A 1 341 ? 12.813 -142.409 38.118 1.00 57.20 ? 412 GLU A CG 1 ATOM 2599 C CD . GLU A 1 341 ? 12.114 -141.088 38.371 1.00 106.88 ? 412 GLU A CD 1 ATOM 2600 O OE1 . GLU A 1 341 ? 11.618 -140.882 39.498 1.00 98.78 ? 412 GLU A OE1 1 ATOM 2601 O OE2 . GLU A 1 341 ? 12.064 -140.254 37.441 1.00 94.75 ? 412 GLU A OE2 1 ATOM 2602 N N . THR A 1 342 ? 17.371 -142.242 38.671 1.00 22.42 ? 413 THR A N 1 ATOM 2603 C CA . THR A 1 342 ? 18.638 -142.142 39.384 1.00 27.09 ? 413 THR A CA 1 ATOM 2604 C C . THR A 1 342 ? 18.433 -141.532 40.771 1.00 23.02 ? 413 THR A C 1 ATOM 2605 O O . THR A 1 342 ? 17.960 -140.403 40.881 1.00 28.75 ? 413 THR A O 1 ATOM 2606 C CB . THR A 1 342 ? 19.643 -141.290 38.595 1.00 30.66 ? 413 THR A CB 1 ATOM 2607 O OG1 . THR A 1 342 ? 19.810 -141.846 37.285 1.00 32.78 ? 413 THR A OG1 1 ATOM 2608 C CG2 . THR A 1 342 ? 20.994 -141.247 39.300 1.00 26.57 ? 413 THR A CG2 1 ATOM 2609 N N . PRO A 1 343 ? 18.782 -142.275 41.837 1.00 18.27 ? 414 PRO A N 1 ATOM 2610 C CA . PRO A 1 343 ? 18.610 -141.725 43.186 1.00 22.09 ? 414 PRO A CA 1 ATOM 2611 C C . PRO A 1 343 ? 19.737 -140.771 43.574 1.00 26.45 ? 414 PRO A C 1 ATOM 2612 O O . PRO A 1 343 ? 20.829 -140.846 43.011 1.00 17.52 ? 414 PRO A O 1 ATOM 2613 C CB . PRO A 1 343 ? 18.616 -142.972 44.068 1.00 22.26 ? 414 PRO A CB 1 ATOM 2614 C CG . PRO A 1 343 ? 19.499 -143.918 43.349 1.00 22.81 ? 414 PRO A CG 1 ATOM 2615 C CD . PRO A 1 343 ? 19.307 -143.652 41.875 1.00 24.01 ? 414 PRO A CD 1 ATOM 2616 N N . ASN A 1 344 ? 19.472 -139.895 44.538 1.00 25.28 ? 415 ASN A N 1 ATOM 2617 C CA . ASN A 1 344 ? 20.426 -138.858 44.914 1.00 31.24 ? 415 ASN A CA 1 ATOM 2618 C C . ASN A 1 344 ? 21.719 -139.388 45.528 1.00 31.50 ? 415 ASN A C 1 ATOM 2619 O O . ASN A 1 344 ? 22.751 -138.721 45.459 1.00 32.41 ? 415 ASN A O 1 ATOM 2620 C CB . ASN A 1 344 ? 19.773 -137.875 45.891 1.00 41.36 ? 415 ASN A CB 1 ATOM 2621 C CG . ASN A 1 344 ? 18.793 -136.934 45.211 1.00 40.64 ? 415 ASN A CG 1 ATOM 2622 O OD1 . ASN A 1 344 ? 19.036 -136.460 44.100 1.00 53.44 ? 415 ASN A OD1 1 ATOM 2623 N ND2 . ASN A 1 344 ? 17.678 -136.657 45.878 1.00 55.37 ? 415 ASN A ND2 1 ATOM 2624 N N . PHE A 1 345 ? 21.683 -140.577 46.124 1.00 21.09 ? 416 PHE A N 1 ATOM 2625 C CA . PHE A 1 345 ? 22.876 -141.085 46.795 1.00 19.90 ? 416 PHE A CA 1 ATOM 2626 C C . PHE A 1 345 ? 23.918 -141.643 45.814 1.00 25.77 ? 416 PHE A C 1 ATOM 2627 O O . PHE A 1 345 ? 24.907 -142.240 46.243 1.00 26.32 ? 416 PHE A O 1 ATOM 2628 C CB . PHE A 1 345 ? 22.503 -142.144 47.847 1.00 25.30 ? 416 PHE A CB 1 ATOM 2629 C CG . PHE A 1 345 ? 21.897 -143.400 47.285 1.00 20.11 ? 416 PHE A CG 1 ATOM 2630 C CD1 . PHE A 1 345 ? 22.701 -144.455 46.888 1.00 24.64 ? 416 PHE A CD1 1 ATOM 2631 C CD2 . PHE A 1 345 ? 20.522 -143.539 47.188 1.00 23.97 ? 416 PHE A CD2 1 ATOM 2632 C CE1 . PHE A 1 345 ? 22.146 -145.617 46.385 1.00 21.79 ? 416 PHE A CE1 1 ATOM 2633 C CE2 . PHE A 1 345 ? 19.961 -144.701 46.684 1.00 24.83 ? 416 PHE A CE2 1 ATOM 2634 C CZ . PHE A 1 345 ? 20.776 -145.739 46.282 1.00 15.84 ? 416 PHE A CZ 1 ATOM 2635 N N . ILE A 1 346 ? 23.712 -141.437 44.511 1.00 22.59 ? 417 ILE A N 1 ATOM 2636 C CA . ILE A 1 346 ? 24.771 -141.687 43.529 1.00 22.28 ? 417 ILE A CA 1 ATOM 2637 C C . ILE A 1 346 ? 24.943 -140.508 42.564 1.00 26.19 ? 417 ILE A C 1 ATOM 2638 O O . ILE A 1 346 ? 25.602 -140.637 41.533 1.00 20.76 ? 417 ILE A O 1 ATOM 2639 C CB . ILE A 1 346 ? 24.523 -142.986 42.713 1.00 26.13 ? 417 ILE A CB 1 ATOM 2640 C CG1 . ILE A 1 346 ? 23.304 -142.871 41.790 1.00 21.91 ? 417 ILE A CG1 1 ATOM 2641 C CG2 . ILE A 1 346 ? 24.359 -144.171 43.652 1.00 28.24 ? 417 ILE A CG2 1 ATOM 2642 C CD1 . ILE A 1 346 ? 23.312 -143.902 40.680 1.00 26.20 ? 417 ILE A CD1 1 ATOM 2643 N N . ILE A 1 347 ? 24.361 -139.361 42.909 1.00 21.73 ? 418 ILE A N 1 ATOM 2644 C CA . ILE A 1 347 ? 24.528 -138.140 42.121 1.00 28.07 ? 418 ILE A CA 1 ATOM 2645 C C . ILE A 1 347 ? 25.554 -137.214 42.782 1.00 26.67 ? 418 ILE A C 1 ATOM 2646 O O . ILE A 1 347 ? 25.331 -136.749 43.899 1.00 31.42 ? 418 ILE A O 1 ATOM 2647 C CB . ILE A 1 347 ? 23.196 -137.380 41.958 1.00 30.62 ? 418 ILE A CB 1 ATOM 2648 C CG1 . ILE A 1 347 ? 22.197 -138.227 41.166 1.00 27.92 ? 418 ILE A CG1 1 ATOM 2649 C CG2 . ILE A 1 347 ? 23.423 -136.050 41.235 1.00 30.34 ? 418 ILE A CG2 1 ATOM 2650 C CD1 . ILE A 1 347 ? 20.786 -137.656 41.128 1.00 26.00 ? 418 ILE A CD1 1 ATOM 2651 N N . PRO A 1 348 ? 26.682 -136.943 42.099 1.00 25.82 ? 419 PRO A N 1 ATOM 2652 C CA . PRO A 1 348 ? 27.658 -135.997 42.659 1.00 32.27 ? 419 PRO A CA 1 ATOM 2653 C C . PRO A 1 348 ? 27.091 -134.585 42.789 1.00 29.56 ? 419 PRO A C 1 ATOM 2654 O O . PRO A 1 348 ? 26.245 -134.194 41.985 1.00 32.42 ? 419 PRO A O 1 ATOM 2655 C CB . PRO A 1 348 ? 28.806 -136.021 41.645 1.00 33.89 ? 419 PRO A CB 1 ATOM 2656 C CG . PRO A 1 348 ? 28.631 -137.275 40.874 1.00 27.28 ? 419 PRO A CG 1 ATOM 2657 C CD . PRO A 1 348 ? 27.168 -137.566 40.857 1.00 27.97 ? 419 PRO A CD 1 ATOM 2658 N N . SER A 1 349 ? 27.554 -133.834 43.784 1.00 33.80 ? 420 SER A N 1 ATOM 2659 C CA . SER A 1 349 ? 27.065 -132.477 44.006 1.00 31.13 ? 420 SER A CA 1 ATOM 2660 C C . SER A 1 349 ? 27.473 -131.535 42.875 1.00 31.94 ? 420 SER A C 1 ATOM 2661 O O . SER A 1 349 ? 26.756 -130.585 42.566 1.00 31.39 ? 420 SER A O 1 ATOM 2662 C CB . SER A 1 349 ? 27.577 -131.941 45.342 1.00 30.98 ? 420 SER A CB 1 ATOM 2663 O OG . SER A 1 349 ? 27.009 -132.662 46.421 1.00 57.17 ? 420 SER A OG 1 ATOM 2664 N N . ASN A 1 350 ? 28.625 -131.804 42.265 1.00 30.61 ? 421 ASN A N 1 ATOM 2665 C CA . ASN A 1 350 ? 29.109 -131.009 41.140 1.00 28.14 ? 421 ASN A CA 1 ATOM 2666 C C . ASN A 1 350 ? 28.463 -131.461 39.829 1.00 31.47 ? 421 ASN A C 1 ATOM 2667 O O . ASN A 1 350 ? 28.758 -132.551 39.347 1.00 31.44 ? 421 ASN A O 1 ATOM 2668 C CB . ASN A 1 350 ? 30.633 -131.112 41.035 1.00 31.09 ? 421 ASN A CB 1 ATOM 2669 C CG . ASN A 1 350 ? 31.211 -130.224 39.940 1.00 38.50 ? 421 ASN A CG 1 ATOM 2670 O OD1 . ASN A 1 350 ? 30.489 -129.479 39.276 1.00 35.36 ? 421 ASN A OD1 1 ATOM 2671 N ND2 . ASN A 1 350 ? 32.524 -130.293 39.759 1.00 30.83 ? 421 ASN A ND2 1 ATOM 2672 N N . PRO A 1 351 ? 27.588 -130.624 39.239 1.00 31.17 ? 422 PRO A N 1 ATOM 2673 C CA . PRO A 1 351 ? 26.894 -131.032 38.009 1.00 38.73 ? 422 PRO A CA 1 ATOM 2674 C C . PRO A 1 351 ? 27.832 -131.366 36.848 1.00 38.19 ? 422 PRO A C 1 ATOM 2675 O O . PRO A 1 351 ? 27.458 -132.132 35.964 1.00 47.16 ? 422 PRO A O 1 ATOM 2676 C CB . PRO A 1 351 ? 26.041 -129.804 37.661 1.00 42.99 ? 422 PRO A CB 1 ATOM 2677 C CG . PRO A 1 351 ? 25.929 -129.033 38.920 1.00 39.49 ? 422 PRO A CG 1 ATOM 2678 C CD . PRO A 1 351 ? 27.211 -129.259 39.643 1.00 40.41 ? 422 PRO A CD 1 ATOM 2679 N N . SER A 1 352 ? 29.036 -130.804 36.860 1.00 39.83 ? 423 SER A N 1 ATOM 2680 C CA . SER A 1 352 ? 29.944 -130.918 35.721 1.00 39.32 ? 423 SER A CA 1 ATOM 2681 C C . SER A 1 352 ? 30.572 -132.304 35.547 1.00 46.52 ? 423 SER A C 1 ATOM 2682 O O . SER A 1 352 ? 31.211 -132.564 34.526 1.00 55.79 ? 423 SER A O 1 ATOM 2683 C CB . SER A 1 352 ? 31.057 -129.875 35.845 1.00 44.54 ? 423 SER A CB 1 ATOM 2684 O OG . SER A 1 352 ? 30.592 -128.592 35.464 1.00 54.72 ? 423 SER A OG 1 ATOM 2685 N N . VAL A 1 353 ? 30.389 -133.188 36.527 1.00 44.10 ? 424 VAL A N 1 ATOM 2686 C CA . VAL A 1 353 ? 31.000 -134.517 36.483 1.00 38.38 ? 424 VAL A CA 1 ATOM 2687 C C . VAL A 1 353 ? 29.962 -135.639 36.497 1.00 37.77 ? 424 VAL A C 1 ATOM 2688 O O . VAL A 1 353 ? 30.318 -136.815 36.560 1.00 46.46 ? 424 VAL A O 1 ATOM 2689 C CB . VAL A 1 353 ? 31.984 -134.728 37.662 1.00 44.45 ? 424 VAL A CB 1 ATOM 2690 C CG1 . VAL A 1 353 ? 33.043 -133.634 37.665 1.00 47.24 ? 424 VAL A CG1 1 ATOM 2691 C CG2 . VAL A 1 353 ? 31.250 -134.771 39.003 1.00 38.42 ? 424 VAL A CG2 1 ATOM 2692 N N . THR A 1 354 ? 28.683 -135.284 36.440 1.00 38.41 ? 425 THR A N 1 ATOM 2693 C CA . THR A 1 354 ? 27.640 -136.294 36.310 1.00 44.32 ? 425 THR A CA 1 ATOM 2694 C C . THR A 1 354 ? 27.683 -136.879 34.902 1.00 43.48 ? 425 THR A C 1 ATOM 2695 O O . THR A 1 354 ? 28.063 -136.188 33.955 1.00 43.11 ? 425 THR A O 1 ATOM 2696 C CB . THR A 1 354 ? 26.240 -135.718 36.585 1.00 46.33 ? 425 THR A CB 1 ATOM 2697 O OG1 . THR A 1 354 ? 25.893 -134.774 35.563 1.00 49.98 ? 425 THR A OG1 1 ATOM 2698 C CG2 . THR A 1 354 ? 26.195 -135.040 37.943 1.00 46.31 ? 425 THR A CG2 1 ATOM 2699 N N . PRO A 1 355 ? 27.304 -138.157 34.754 1.00 47.65 ? 426 PRO A N 1 ATOM 2700 C CA . PRO A 1 355 ? 27.305 -138.750 33.417 1.00 48.64 ? 426 PRO A CA 1 ATOM 2701 C C . PRO A 1 355 ? 26.029 -138.406 32.660 1.00 48.36 ? 426 PRO A C 1 ATOM 2702 O O . PRO A 1 355 ? 25.040 -138.033 33.291 1.00 38.98 ? 426 PRO A O 1 ATOM 2703 C CB . PRO A 1 355 ? 27.387 -140.244 33.707 1.00 47.53 ? 426 PRO A CB 1 ATOM 2704 C CG . PRO A 1 355 ? 26.607 -140.392 34.971 1.00 50.57 ? 426 PRO A CG 1 ATOM 2705 C CD . PRO A 1 355 ? 26.864 -139.127 35.774 1.00 48.47 ? 426 PRO A CD 1 ATOM 2706 N N . PRO A 1 356 ? 26.050 -138.516 31.324 1.00 48.39 ? 427 PRO A N 1 ATOM 2707 C CA . PRO A 1 356 ? 24.822 -138.312 30.550 1.00 52.70 ? 427 PRO A CA 1 ATOM 2708 C C . PRO A 1 356 ? 23.704 -139.268 30.959 1.00 42.54 ? 427 PRO A C 1 ATOM 2709 O O . PRO A 1 356 ? 23.946 -140.462 31.136 1.00 46.54 ? 427 PRO A O 1 ATOM 2710 C CB . PRO A 1 356 ? 25.263 -138.579 29.103 1.00 48.01 ? 427 PRO A CB 1 ATOM 2711 C CG . PRO A 1 356 ? 26.603 -139.250 29.203 1.00 49.19 ? 427 PRO A CG 1 ATOM 2712 C CD . PRO A 1 356 ? 27.217 -138.738 30.456 1.00 51.66 ? 427 PRO A CD 1 ATOM 2713 N N . THR A 1 357 ? 22.496 -138.736 31.120 1.00 41.20 ? 428 THR A N 1 ATOM 2714 C CA . THR A 1 357 ? 21.320 -139.569 31.331 1.00 35.57 ? 428 THR A CA 1 ATOM 2715 C C . THR A 1 357 ? 21.002 -140.326 30.044 1.00 44.34 ? 428 THR A C 1 ATOM 2716 O O . THR A 1 357 ? 21.497 -139.964 28.976 1.00 39.59 ? 428 THR A O 1 ATOM 2717 C CB . THR A 1 357 ? 20.092 -138.736 31.742 1.00 49.09 ? 428 THR A CB 1 ATOM 2718 O OG1 . THR A 1 357 ? 19.784 -137.793 30.708 1.00 41.81 ? 428 THR A OG1 1 ATOM 2719 C CG2 . THR A 1 357 ? 20.355 -137.992 33.039 1.00 42.54 ? 428 THR A CG2 1 ATOM 2720 N N . PRO A 1 358 ? 20.184 -141.386 30.139 1.00 45.08 ? 429 PRO A N 1 ATOM 2721 C CA . PRO A 1 358 ? 19.731 -142.074 28.924 1.00 42.40 ? 429 PRO A CA 1 ATOM 2722 C C . PRO A 1 358 ? 18.990 -141.141 27.968 1.00 36.98 ? 429 PRO A C 1 ATOM 2723 O O . PRO A 1 358 ? 19.121 -141.280 26.751 1.00 30.97 ? 429 PRO A O 1 ATOM 2724 C CB . PRO A 1 358 ? 18.797 -143.160 29.464 1.00 36.86 ? 429 PRO A CB 1 ATOM 2725 C CG . PRO A 1 358 ? 19.286 -143.423 30.843 1.00 40.29 ? 429 PRO A CG 1 ATOM 2726 C CD . PRO A 1 358 ? 19.783 -142.103 31.362 1.00 42.14 ? 429 PRO A CD 1 ATOM 2727 N N . GLU A 1 359 ? 18.227 -140.199 28.517 1.00 29.80 ? 430 GLU A N 1 ATOM 2728 C CA . GLU A 1 359 ? 17.491 -139.237 27.703 1.00 38.77 ? 430 GLU A CA 1 ATOM 2729 C C . GLU A 1 359 ? 18.458 -138.352 26.922 1.00 39.26 ? 430 GLU A C 1 ATOM 2730 O O . GLU A 1 359 ? 18.224 -138.035 25.755 1.00 38.77 ? 430 GLU A O 1 ATOM 2731 C CB . GLU A 1 359 ? 16.576 -138.373 28.574 1.00 46.98 ? 430 GLU A CB 1 ATOM 2732 C CG . GLU A 1 359 ? 15.661 -139.164 29.499 1.00 87.04 ? 430 GLU A CG 1 ATOM 2733 C CD . GLU A 1 359 ? 16.236 -139.328 30.894 1.00 106.99 ? 430 GLU A CD 1 ATOM 2734 O OE1 . GLU A 1 359 ? 16.373 -138.310 31.606 1.00 95.53 ? 430 GLU A OE1 1 ATOM 2735 O OE2 . GLU A 1 359 ? 16.553 -140.474 31.279 1.00 67.69 ? 430 GLU A OE2 1 ATOM 2736 N N . THR A 1 360 ? 19.547 -137.959 27.575 1.00 32.96 ? 431 THR A N 1 ATOM 2737 C CA . THR A 1 360 ? 20.569 -137.135 26.941 1.00 36.45 ? 431 THR A CA 1 ATOM 2738 C C . THR A 1 360 ? 21.341 -137.940 25.902 1.00 26.89 ? 431 THR A C 1 ATOM 2739 O O . THR A 1 360 ? 21.516 -137.498 24.767 1.00 35.55 ? 431 THR A O 1 ATOM 2740 C CB . THR A 1 360 ? 21.556 -136.563 27.982 1.00 40.59 ? 431 THR A CB 1 ATOM 2741 O OG1 . THR A 1 360 ? 20.854 -135.700 28.884 1.00 41.82 ? 431 THR A OG1 1 ATOM 2742 C CG2 . THR A 1 360 ? 22.672 -135.770 27.306 1.00 43.87 ? 431 THR A CG2 1 ATOM 2743 N N . ALA A 1 361 ? 21.797 -139.123 26.297 1.00 29.51 ? 432 ALA A N 1 ATOM 2744 C CA . ALA A 1 361 ? 22.617 -139.961 25.428 1.00 24.99 ? 432 ALA A CA 1 ATOM 2745 C C . ALA A 1 361 ? 21.874 -140.378 24.156 1.00 25.39 ? 432 ALA A C 1 ATOM 2746 O O . ALA A 1 361 ? 22.487 -140.540 23.101 1.00 28.95 ? 432 ALA A O 1 ATOM 2747 C CB . ALA A 1 361 ? 23.086 -141.190 26.186 1.00 31.86 ? 432 ALA A CB 1 ATOM 2748 N N . LEU A 1 362 ? 20.558 -140.545 24.265 1.00 24.57 ? 433 LEU A N 1 ATOM 2749 C CA . LEU A 1 362 ? 19.739 -141.020 23.150 1.00 29.03 ? 433 LEU A CA 1 ATOM 2750 C C . LEU A 1 362 ? 18.939 -139.892 22.509 1.00 29.48 ? 433 LEU A C 1 ATOM 2751 O O . LEU A 1 362 ? 17.964 -140.138 21.798 1.00 29.89 ? 433 LEU A O 1 ATOM 2752 C CB . LEU A 1 362 ? 18.788 -142.118 23.630 1.00 28.30 ? 433 LEU A CB 1 ATOM 2753 C CG . LEU A 1 362 ? 19.455 -143.329 24.284 1.00 24.52 ? 433 LEU A CG 1 ATOM 2754 C CD1 . LEU A 1 362 ? 18.402 -144.294 24.803 1.00 30.94 ? 433 LEU A CD1 1 ATOM 2755 C CD2 . LEU A 1 362 ? 20.389 -144.028 23.307 1.00 32.00 ? 433 LEU A CD2 1 ATOM 2756 N N . GLN A 1 363 ? 19.357 -138.657 22.759 1.00 26.39 ? 434 GLN A N 1 ATOM 2757 C CA . GLN A 1 363 ? 18.627 -137.495 22.272 1.00 30.54 ? 434 GLN A CA 1 ATOM 2758 C C . GLN A 1 363 ? 18.856 -137.286 20.783 1.00 25.96 ? 434 GLN A C 1 ATOM 2759 O O . GLN A 1 363 ? 19.882 -137.685 20.233 1.00 30.70 ? 434 GLN A O 1 ATOM 2760 C CB . GLN A 1 363 ? 19.042 -136.234 23.039 1.00 30.52 ? 434 GLN A CB 1 ATOM 2761 C CG . GLN A 1 363 ? 20.376 -135.641 22.592 1.00 40.73 ? 434 GLN A CG 1 ATOM 2762 C CD . GLN A 1 363 ? 20.877 -134.554 23.525 1.00 53.86 ? 434 GLN A CD 1 ATOM 2763 O OE1 . GLN A 1 363 ? 20.090 -133.846 24.152 1.00 53.83 ? 434 GLN A OE1 1 ATOM 2764 N NE2 . GLN A 1 363 ? 22.196 -134.421 23.622 1.00 59.50 ? 434 GLN A NE2 1 ATOM 2765 N N . CYS A 1 364 ? 17.882 -136.655 20.141 1.00 24.75 ? 435 CYS A N 1 ATOM 2766 C CA . CYS A 1 364 ? 18.003 -136.248 18.752 1.00 39.70 ? 435 CYS A CA 1 ATOM 2767 C C . CYS A 1 364 ? 16.988 -135.149 18.484 1.00 36.19 ? 435 CYS A C 1 ATOM 2768 O O . CYS A 1 364 ? 16.039 -134.979 19.248 1.00 28.45 ? 435 CYS A O 1 ATOM 2769 C CB . CYS A 1 364 ? 17.772 -137.430 17.810 1.00 33.96 ? 435 CYS A CB 1 ATOM 2770 S SG . CYS A 1 364 ? 16.105 -138.125 17.920 1.00 40.08 ? 435 CYS A SG 1 ATOM 2771 N N . THR A 1 365 ? 17.203 -134.398 17.410 1.00 38.02 ? 436 THR A N 1 ATOM 2772 C CA . THR A 1 365 ? 16.219 -133.433 16.932 1.00 41.01 ? 436 THR A CA 1 ATOM 2773 C C . THR A 1 365 ? 15.876 -133.782 15.494 1.00 36.80 ? 436 THR A C 1 ATOM 2774 O O . THR A 1 365 ? 16.764 -134.057 14.685 1.00 32.02 ? 436 THR A O 1 ATOM 2775 C CB . THR A 1 365 ? 16.730 -131.983 17.027 1.00 53.50 ? 436 THR A CB 1 ATOM 2776 O OG1 . THR A 1 365 ? 18.052 -131.898 16.483 1.00 58.69 ? 436 THR A OG1 1 ATOM 2777 C CG2 . THR A 1 365 ? 16.751 -131.522 18.478 1.00 56.93 ? 436 THR A CG2 1 ATOM 2778 N N . ALA A 1 366 ? 14.582 -133.773 15.191 1.00 30.30 ? 437 ALA A N 1 ATOM 2779 C CA . ALA A 1 366 ? 14.069 -134.270 13.919 1.00 49.45 ? 437 ALA A CA 1 ATOM 2780 C C . ALA A 1 366 ? 14.696 -133.575 12.711 1.00 43.20 ? 437 ALA A C 1 ATOM 2781 O O . ALA A 1 366 ? 14.881 -134.195 11.664 1.00 33.37 ? 437 ALA A O 1 ATOM 2782 C CB . ALA A 1 366 ? 12.550 -134.117 13.878 1.00 43.54 ? 437 ALA A CB 1 ATOM 2783 N N . ASP A 1 367 ? 15.027 -132.297 12.858 1.00 39.98 ? 438 ASP A N 1 ATOM 2784 C CA . ASP A 1 367 ? 15.535 -131.515 11.735 1.00 47.73 ? 438 ASP A CA 1 ATOM 2785 C C . ASP A 1 367 ? 17.020 -131.779 11.466 1.00 42.36 ? 438 ASP A C 1 ATOM 2786 O O . ASP A 1 367 ? 17.545 -131.374 10.427 1.00 49.81 ? 438 ASP A O 1 ATOM 2787 C CB . ASP A 1 367 ? 15.301 -130.022 11.982 1.00 46.90 ? 438 ASP A CB 1 ATOM 2788 C CG . ASP A 1 367 ? 16.039 -129.508 13.200 1.00 79.48 ? 438 ASP A CG 1 ATOM 2789 O OD1 . ASP A 1 367 ? 15.554 -129.733 14.330 1.00 87.56 ? 438 ASP A OD1 1 ATOM 2790 O OD2 . ASP A 1 367 ? 17.104 -128.879 13.028 1.00 87.87 ? 438 ASP A OD2 1 ATOM 2791 N N . LYS A 1 368 ? 17.686 -132.459 12.398 1.00 36.65 ? 439 LYS A N 1 ATOM 2792 C CA . LYS A 1 368 ? 19.100 -132.812 12.250 1.00 38.00 ? 439 LYS A CA 1 ATOM 2793 C C . LYS A 1 368 ? 19.311 -134.324 12.177 1.00 41.53 ? 439 LYS A C 1 ATOM 2794 O O . LYS A 1 368 ? 20.420 -134.787 11.906 1.00 48.08 ? 439 LYS A O 1 ATOM 2795 C CB . LYS A 1 368 ? 19.917 -132.244 13.414 1.00 49.34 ? 439 LYS A CB 1 ATOM 2796 C CG . LYS A 1 368 ? 19.918 -130.726 13.496 1.00 63.06 ? 439 LYS A CG 1 ATOM 2797 C CD . LYS A 1 368 ? 20.483 -130.243 14.825 1.00 115.52 ? 439 LYS A CD 1 ATOM 2798 C CE . LYS A 1 368 ? 20.031 -128.826 15.152 1.00 104.76 ? 439 LYS A CE 1 ATOM 2799 N NZ . LYS A 1 368 ? 20.676 -127.803 14.284 1.00 101.51 ? 439 LYS A NZ 1 ATOM 2800 N N . PHE A 1 369 ? 18.247 -135.085 12.420 1.00 34.57 ? 440 PHE A N 1 ATOM 2801 C CA . PHE A 1 369 ? 18.328 -136.543 12.476 1.00 36.19 ? 440 PHE A CA 1 ATOM 2802 C C . PHE A 1 369 ? 17.375 -137.173 11.465 1.00 34.33 ? 440 PHE A C 1 ATOM 2803 O O . PHE A 1 369 ? 16.160 -137.161 11.668 1.00 37.95 ? 440 PHE A O 1 ATOM 2804 C CB . PHE A 1 369 ? 17.999 -137.039 13.882 1.00 32.78 ? 440 PHE A CB 1 ATOM 2805 C CG . PHE A 1 369 ? 18.423 -138.454 14.138 1.00 36.02 ? 440 PHE A CG 1 ATOM 2806 C CD1 . PHE A 1 369 ? 17.611 -139.516 13.778 1.00 40.50 ? 440 PHE A CD1 1 ATOM 2807 C CD2 . PHE A 1 369 ? 19.639 -138.722 14.742 1.00 29.54 ? 440 PHE A CD2 1 ATOM 2808 C CE1 . PHE A 1 369 ? 18.006 -140.818 14.015 1.00 37.27 ? 440 PHE A CE1 1 ATOM 2809 C CE2 . PHE A 1 369 ? 20.038 -140.020 14.982 1.00 33.36 ? 440 PHE A CE2 1 ATOM 2810 C CZ . PHE A 1 369 ? 19.221 -141.069 14.619 1.00 31.93 ? 440 PHE A CZ 1 ATOM 2811 N N . PRO A 1 370 ? 17.919 -137.733 10.372 1.00 37.48 ? 441 PRO A N 1 ATOM 2812 C CA . PRO A 1 370 ? 17.030 -138.232 9.319 1.00 36.62 ? 441 PRO A CA 1 ATOM 2813 C C . PRO A 1 370 ? 16.515 -139.651 9.517 1.00 25.84 ? 441 PRO A C 1 ATOM 2814 O O . PRO A 1 370 ? 17.247 -140.529 9.974 1.00 35.34 ? 441 PRO A O 1 ATOM 2815 C CB . PRO A 1 370 ? 17.911 -138.162 8.073 1.00 37.02 ? 441 PRO A CB 1 ATOM 2816 C CG . PRO A 1 370 ? 19.280 -138.433 8.595 1.00 50.71 ? 441 PRO A CG 1 ATOM 2817 C CD . PRO A 1 370 ? 19.335 -137.805 9.966 1.00 41.46 ? 441 PRO A CD 1 ATOM 2818 N N . ASP A 1 371 ? 15.246 -139.851 9.168 1.00 28.48 ? 442 ASP A N 1 ATOM 2819 C CA . ASP A 1 371 ? 14.672 -141.185 9.046 1.00 29.13 ? 442 ASP A CA 1 ATOM 2820 C C . ASP A 1 371 ? 15.498 -141.995 8.057 1.00 32.15 ? 442 ASP A C 1 ATOM 2821 O O . ASP A 1 371 ? 15.674 -141.586 6.909 1.00 40.87 ? 442 ASP A O 1 ATOM 2822 C CB . ASP A 1 371 ? 13.214 -141.118 8.577 1.00 33.79 ? 442 ASP A CB 1 ATOM 2823 C CG . ASP A 1 371 ? 12.255 -140.728 9.687 1.00 47.59 ? 442 ASP A CG 1 ATOM 2824 O OD1 . ASP A 1 371 ? 12.660 -139.977 10.598 1.00 51.96 ? 442 ASP A OD1 1 ATOM 2825 O OD2 . ASP A 1 371 ? 11.088 -141.175 9.645 1.00 72.63 ? 442 ASP A OD2 1 ATOM 2826 N N . SER A 1 372 ? 15.982 -143.138 8.488 1.00 25.90 ? 443 SER A N 1 ATOM 2827 C CA . SER A 1 372 ? 16.733 -143.981 7.600 1.00 35.80 ? 443 SER A CA 1 ATOM 2828 C C . SER A 1 372 ? 16.263 -145.421 7.625 1.00 38.16 ? 443 SER A C 1 ATOM 2829 O O . SER A 1 372 ? 15.710 -145.880 8.601 1.00 41.06 ? 443 SER A O 1 ATOM 2830 C CB . SER A 1 372 ? 18.225 -143.907 7.878 1.00 33.43 ? 443 SER A CB 1 ATOM 2831 O OG . SER A 1 372 ? 18.489 -143.721 9.238 1.00 62.17 ? 443 SER A OG 1 ATOM 2832 N N . PHE A 1 373 ? 16.478 -146.110 6.522 1.00 28.18 ? 444 PHE A N 1 ATOM 2833 C CA . PHE A 1 373 ? 16.163 -147.524 6.400 1.00 22.93 ? 444 PHE A CA 1 ATOM 2834 C C . PHE A 1 373 ? 17.438 -148.272 6.029 1.00 28.62 ? 444 PHE A C 1 ATOM 2835 O O . PHE A 1 373 ? 18.218 -147.802 5.202 1.00 27.62 ? 444 PHE A O 1 ATOM 2836 C CB . PHE A 1 373 ? 15.074 -147.766 5.351 1.00 26.99 ? 444 PHE A CB 1 ATOM 2837 C CG . PHE A 1 373 ? 13.717 -147.249 5.747 1.00 30.69 ? 444 PHE A CG 1 ATOM 2838 C CD1 . PHE A 1 373 ? 12.833 -148.050 6.453 1.00 31.65 ? 444 PHE A CD1 1 ATOM 2839 C CD2 . PHE A 1 373 ? 13.322 -145.966 5.403 1.00 34.41 ? 444 PHE A CD2 1 ATOM 2840 C CE1 . PHE A 1 373 ? 11.581 -147.578 6.814 1.00 32.62 ? 444 PHE A CE1 1 ATOM 2841 C CE2 . PHE A 1 373 ? 12.073 -145.488 5.762 1.00 40.87 ? 444 PHE A CE2 1 ATOM 2842 C CZ . PHE A 1 373 ? 11.202 -146.296 6.468 1.00 32.75 ? 444 PHE A CZ 1 ATOM 2843 N N . GLY A 1 374 ? 17.652 -149.426 6.651 1.00 26.05 ? 445 GLY A N 1 ATOM 2844 C CA . GLY A 1 374 ? 18.794 -150.261 6.331 1.00 25.76 ? 445 GLY A CA 1 ATOM 2845 C C . GLY A 1 374 ? 18.473 -151.195 5.183 1.00 31.94 ? 445 GLY A C 1 ATOM 2846 O O . GLY A 1 374 ? 17.326 -151.271 4.742 1.00 26.59 ? 445 GLY A O 1 ATOM 2847 N N . ALA A 1 375 ? 19.487 -151.901 4.694 1.00 35.25 ? 446 ALA A N 1 ATOM 2848 C CA . ALA A 1 375 ? 19.285 -152.882 3.636 1.00 33.07 ? 446 ALA A CA 1 ATOM 2849 C C . ALA A 1 375 ? 18.507 -154.069 4.184 1.00 37.99 ? 446 ALA A C 1 ATOM 2850 O O . ALA A 1 375 ? 18.527 -154.331 5.387 1.00 34.74 ? 446 ALA A O 1 ATOM 2851 C CB . ALA A 1 375 ? 20.617 -153.332 3.059 1.00 36.91 ? 446 ALA A CB 1 ATOM 2852 N N . CYS A 1 376 ? 17.821 -154.784 3.301 1.00 41.12 ? 447 CYS A N 1 ATOM 2853 C CA . CYS A 1 376 ? 16.968 -155.887 3.722 1.00 41.21 ? 447 CYS A CA 1 ATOM 2854 C C . CYS A 1 376 ? 17.771 -157.058 4.275 1.00 49.26 ? 447 CYS A C 1 ATOM 2855 O O . CYS A 1 376 ? 18.766 -157.480 3.685 1.00 41.62 ? 447 CYS A O 1 ATOM 2856 C CB . CYS A 1 376 ? 16.104 -156.373 2.557 1.00 45.33 ? 447 CYS A CB 1 ATOM 2857 S SG . CYS A 1 376 ? 14.879 -157.622 3.025 1.00 63.84 ? 447 CYS A SG 1 ATOM 2858 N N . ASP A 1 377 ? 17.329 -157.565 5.421 1.00 39.06 ? 448 ASP A N 1 ATOM 2859 C CA . ASP A 1 377 ? 17.819 -158.829 5.953 1.00 49.21 ? 448 ASP A CA 1 ATOM 2860 C C . ASP A 1 377 ? 16.928 -159.928 5.389 1.00 45.61 ? 448 ASP A C 1 ATOM 2861 O O . ASP A 1 377 ? 15.843 -160.187 5.910 1.00 41.90 ? 448 ASP A O 1 ATOM 2862 C CB . ASP A 1 377 ? 17.806 -158.823 7.486 1.00 49.97 ? 448 ASP A CB 1 ATOM 2863 C CG . ASP A 1 377 ? 18.142 -160.177 8.084 1.00 58.12 ? 448 ASP A CG 1 ATOM 2864 O OD1 . ASP A 1 377 ? 18.844 -160.970 7.421 1.00 62.39 ? 448 ASP A OD1 1 ATOM 2865 O OD2 . ASP A 1 377 ? 17.705 -160.445 9.224 1.00 50.06 ? 448 ASP A OD2 1 ATOM 2866 N N . VAL A 1 378 ? 17.389 -160.557 4.311 1.00 43.74 ? 449 VAL A N 1 ATOM 2867 C CA . VAL A 1 378 ? 16.563 -161.484 3.541 1.00 63.50 ? 449 VAL A CA 1 ATOM 2868 C C . VAL A 1 378 ? 16.150 -162.715 4.342 1.00 55.34 ? 449 VAL A C 1 ATOM 2869 O O . VAL A 1 378 ? 15.121 -163.330 4.060 1.00 55.14 ? 449 VAL A O 1 ATOM 2870 C CB . VAL A 1 378 ? 17.293 -161.950 2.261 1.00 60.42 ? 449 VAL A CB 1 ATOM 2871 C CG1 . VAL A 1 378 ? 17.573 -160.762 1.351 1.00 55.45 ? 449 VAL A CG1 1 ATOM 2872 C CG2 . VAL A 1 378 ? 18.588 -162.683 2.605 1.00 51.07 ? 449 VAL A CG2 1 ATOM 2873 N N . GLN A 1 379 ? 16.951 -163.069 5.339 1.00 56.11 ? 450 GLN A N 1 ATOM 2874 C CA . GLN A 1 379 ? 16.684 -164.251 6.150 1.00 50.64 ? 450 GLN A CA 1 ATOM 2875 C C . GLN A 1 379 ? 15.426 -164.065 6.996 1.00 54.16 ? 450 GLN A C 1 ATOM 2876 O O . GLN A 1 379 ? 14.668 -165.011 7.214 1.00 58.43 ? 450 GLN A O 1 ATOM 2877 C CB . GLN A 1 379 ? 17.887 -164.557 7.043 1.00 64.37 ? 450 GLN A CB 1 ATOM 2878 C CG . GLN A 1 379 ? 18.237 -166.037 7.135 1.00 81.28 ? 450 GLN A CG 1 ATOM 2879 C CD . GLN A 1 379 ? 19.685 -166.276 7.528 1.00 103.80 ? 450 GLN A CD 1 ATOM 2880 O OE1 . GLN A 1 379 ? 20.575 -165.505 7.169 1.00 97.64 ? 450 GLN A OE1 1 ATOM 2881 N NE2 . GLN A 1 379 ? 19.926 -167.350 8.269 1.00 106.63 ? 450 GLN A NE2 1 ATOM 2882 N N . ALA A 1 380 ? 15.213 -162.838 7.463 1.00 55.66 ? 451 ALA A N 1 ATOM 2883 C CA . ALA A 1 380 ? 14.044 -162.499 8.271 1.00 50.46 ? 451 ALA A CA 1 ATOM 2884 C C . ALA A 1 380 ? 13.047 -161.664 7.473 1.00 46.72 ? 451 ALA A C 1 ATOM 2885 O O . ALA A 1 380 ? 11.901 -161.487 7.889 1.00 48.48 ? 451 ALA A O 1 ATOM 2886 C CB . ALA A 1 380 ? 14.471 -161.751 9.522 1.00 49.97 ? 451 ALA A CB 1 ATOM 2887 N N . CYS A 1 381 ? 13.493 -161.157 6.327 1.00 46.72 ? 452 CYS A N 1 ATOM 2888 C CA . CYS A 1 381 ? 12.684 -160.269 5.498 1.00 58.35 ? 452 CYS A CA 1 ATOM 2889 C C . CYS A 1 381 ? 12.267 -159.036 6.300 1.00 45.84 ? 452 CYS A C 1 ATOM 2890 O O . CYS A 1 381 ? 11.120 -158.590 6.239 1.00 42.96 ? 452 CYS A O 1 ATOM 2891 C CB . CYS A 1 381 ? 11.458 -161.005 4.948 1.00 59.73 ? 452 CYS A CB 1 ATOM 2892 S SG . CYS A 1 381 ? 10.971 -160.450 3.294 1.00 72.11 ? 452 CYS A SG 1 ATOM 2893 N N . LYS A 1 382 ? 13.219 -158.498 7.057 1.00 41.73 ? 453 LYS A N 1 ATOM 2894 C CA . LYS A 1 382 ? 13.017 -157.266 7.805 1.00 34.47 ? 453 LYS A CA 1 ATOM 2895 C C . LYS A 1 382 ? 14.200 -156.339 7.590 1.00 28.03 ? 453 LYS A C 1 ATOM 2896 O O . LYS A 1 382 ? 15.279 -156.780 7.193 1.00 29.34 ? 453 LYS A O 1 ATOM 2897 C CB . LYS A 1 382 ? 12.838 -157.553 9.297 1.00 36.63 ? 453 LYS A CB 1 ATOM 2898 C CG . LYS A 1 382 ? 11.585 -158.348 9.616 1.00 38.38 ? 453 LYS A CG 1 ATOM 2899 C CD . LYS A 1 382 ? 11.072 -158.071 11.023 1.00 57.35 ? 453 LYS A CD 1 ATOM 2900 C CE . LYS A 1 382 ? 9.554 -158.133 11.079 1.00 72.62 ? 453 LYS A CE 1 ATOM 2901 N NZ . LYS A 1 382 ? 8.921 -157.048 10.272 1.00 67.82 ? 453 LYS A NZ 1 ATOM 2902 N N . ARG A 1 383 ? 13.991 -155.053 7.844 1.00 30.95 ? 454 ARG A N 1 ATOM 2903 C CA . ARG A 1 383 ? 15.065 -154.079 7.740 1.00 30.82 ? 454 ARG A CA 1 ATOM 2904 C C . ARG A 1 383 ? 15.002 -153.073 8.877 1.00 23.00 ? 454 ARG A C 1 ATOM 2905 O O . ARG A 1 383 ? 13.939 -152.821 9.450 1.00 21.43 ? 454 ARG A O 1 ATOM 2906 C CB . ARG A 1 383 ? 15.007 -153.356 6.396 1.00 23.82 ? 454 ARG A CB 1 ATOM 2907 C CG . ARG A 1 383 ? 13.733 -152.562 6.174 1.00 30.33 ? 454 ARG A CG 1 ATOM 2908 C CD . ARG A 1 383 ? 13.716 -151.928 4.792 1.00 30.75 ? 454 ARG A CD 1 ATOM 2909 N NE . ARG A 1 383 ? 12.508 -151.136 4.578 1.00 28.20 ? 454 ARG A NE 1 ATOM 2910 C CZ . ARG A 1 383 ? 12.386 -150.182 3.660 1.00 32.81 ? 454 ARG A CZ 1 ATOM 2911 N NH1 . ARG A 1 383 ? 13.402 -149.887 2.858 1.00 30.98 ? 454 ARG A NH1 1 ATOM 2912 N NH2 . ARG A 1 383 ? 11.246 -149.516 3.547 1.00 26.59 ? 454 ARG A NH2 1 ATOM 2913 N N . GLN A 1 384 ? 16.158 -152.502 9.191 1.00 22.68 ? 455 GLN A N 1 ATOM 2914 C CA . GLN A 1 384 ? 16.258 -151.479 10.217 1.00 22.54 ? 455 GLN A CA 1 ATOM 2915 C C . GLN A 1 384 ? 15.515 -150.218 9.802 1.00 21.22 ? 455 GLN A C 1 ATOM 2916 O O . GLN A 1 384 ? 15.589 -149.793 8.650 1.00 27.37 ? 455 GLN A O 1 ATOM 2917 C CB . GLN A 1 384 ? 17.727 -151.144 10.496 1.00 23.31 ? 455 GLN A CB 1 ATOM 2918 C CG . GLN A 1 384 ? 17.946 -150.093 11.587 1.00 21.70 ? 455 GLN A CG 1 ATOM 2919 C CD . GLN A 1 384 ? 17.587 -150.597 12.975 1.00 26.51 ? 455 GLN A CD 1 ATOM 2920 O OE1 . GLN A 1 384 ? 17.604 -151.801 13.235 1.00 20.68 ? 455 GLN A OE1 1 ATOM 2921 N NE2 . GLN A 1 384 ? 17.260 -149.675 13.875 1.00 24.19 ? 455 GLN A NE2 1 ATOM 2922 N N . LYS A 1 385 ? 14.785 -149.642 10.751 1.00 21.35 ? 456 LYS A N 1 ATOM 2923 C CA . LYS A 1 385 ? 14.304 -148.276 10.638 1.00 20.90 ? 456 LYS A CA 1 ATOM 2924 C C . LYS A 1 385 ? 14.787 -147.510 11.857 1.00 21.37 ? 456 LYS A C 1 ATOM 2925 O O . LYS A 1 385 ? 14.523 -147.901 13.000 1.00 25.83 ? 456 LYS A O 1 ATOM 2926 C CB . LYS A 1 385 ? 12.782 -148.198 10.539 1.00 25.36 ? 456 LYS A CB 1 ATOM 2927 C CG . LYS A 1 385 ? 12.292 -146.786 10.224 1.00 27.76 ? 456 LYS A CG 1 ATOM 2928 C CD . LYS A 1 385 ? 10.805 -146.610 10.449 1.00 31.77 ? 456 LYS A CD 1 ATOM 2929 C CE . LYS A 1 385 ? 10.374 -145.204 10.061 1.00 36.61 ? 456 LYS A CE 1 ATOM 2930 N NZ . LYS A 1 385 ? 8.947 -144.934 10.375 1.00 40.97 ? 456 LYS A NZ 1 ATOM 2931 N N . THR A 1 386 ? 15.504 -146.425 11.593 1.00 19.26 ? 457 THR A N 1 ATOM 2932 C CA . THR A 1 386 ? 16.018 -145.548 12.629 1.00 24.41 ? 457 THR A CA 1 ATOM 2933 C C . THR A 1 386 ? 15.458 -144.155 12.400 1.00 28.19 ? 457 THR A C 1 ATOM 2934 O O . THR A 1 386 ? 15.530 -143.629 11.289 1.00 26.50 ? 457 THR A O 1 ATOM 2935 C CB . THR A 1 386 ? 17.556 -145.501 12.622 1.00 19.31 ? 457 THR A CB 1 ATOM 2936 O OG1 . THR A 1 386 ? 18.074 -146.835 12.692 1.00 29.01 ? 457 THR A OG1 1 ATOM 2937 C CG2 . THR A 1 386 ? 18.079 -144.685 13.803 1.00 31.53 ? 457 THR A CG2 1 ATOM 2938 N N . SER A 1 387 ? 14.888 -143.560 13.443 1.00 22.03 ? 458 SER A N 1 ATOM 2939 C CA . SER A 1 387 ? 14.290 -142.236 13.304 1.00 27.55 ? 458 SER A CA 1 ATOM 2940 C C . SER A 1 387 ? 14.315 -141.460 14.615 1.00 27.14 ? 458 SER A C 1 ATOM 2941 O O . SER A 1 387 ? 14.822 -141.945 15.622 1.00 25.09 ? 458 SER A O 1 ATOM 2942 C CB . SER A 1 387 ? 12.851 -142.358 12.797 1.00 21.48 ? 458 SER A CB 1 ATOM 2943 O OG . SER A 1 387 ? 12.062 -143.130 13.681 1.00 37.89 ? 458 SER A OG 1 ATOM 2944 N N . CYS A 1 388 ? 13.774 -140.245 14.581 1.00 26.93 ? 459 CYS A N 1 ATOM 2945 C CA . CYS A 1 388 ? 13.697 -139.390 15.759 1.00 33.47 ? 459 CYS A CA 1 ATOM 2946 C C . CYS A 1 388 ? 12.239 -139.130 16.112 1.00 34.70 ? 459 CYS A C 1 ATOM 2947 O O . CYS A 1 388 ? 11.487 -138.586 15.302 1.00 33.00 ? 459 CYS A O 1 ATOM 2948 C CB . CYS A 1 388 ? 14.428 -138.067 15.514 1.00 36.07 ? 459 CYS A CB 1 ATOM 2949 S SG . CYS A 1 388 ? 14.652 -137.043 16.991 1.00 42.75 ? 459 CYS A SG 1 ATOM 2950 N N . VAL A 1 389 ? 11.842 -139.527 17.318 1.00 29.08 ? 460 VAL A N 1 ATOM 2951 C CA . VAL A 1 389 ? 10.478 -139.301 17.791 1.00 35.70 ? 460 VAL A CA 1 ATOM 2952 C C . VAL A 1 389 ? 10.518 -138.792 19.223 1.00 31.10 ? 460 VAL A C 1 ATOM 2953 O O . VAL A 1 389 ? 11.225 -139.341 20.070 1.00 31.20 ? 460 VAL A O 1 ATOM 2954 C CB . VAL A 1 389 ? 9.620 -140.583 17.719 1.00 39.79 ? 460 VAL A CB 1 ATOM 2955 C CG1 . VAL A 1 389 ? 8.216 -140.335 18.262 1.00 35.34 ? 460 VAL A CG1 1 ATOM 2956 C CG2 . VAL A 1 389 ? 9.545 -141.091 16.286 1.00 39.58 ? 460 VAL A CG2 1 ATOM 2957 N N . GLY A 1 390 ? 9.757 -137.734 19.483 1.00 34.16 ? 461 GLY A N 1 ATOM 2958 C CA . GLY A 1 390 ? 9.724 -137.119 20.796 1.00 28.46 ? 461 GLY A CA 1 ATOM 2959 C C . GLY A 1 390 ? 11.099 -136.677 21.257 1.00 33.74 ? 461 GLY A C 1 ATOM 2960 O O . GLY A 1 390 ? 11.362 -136.574 22.455 1.00 34.35 ? 461 GLY A O 1 ATOM 2961 N N . GLY A 1 391 ? 11.981 -136.417 20.298 1.00 28.53 ? 462 GLY A N 1 ATOM 2962 C CA . GLY A 1 391 ? 13.335 -135.993 20.597 1.00 22.04 ? 462 GLY A CA 1 ATOM 2963 C C . GLY A 1 391 ? 14.228 -137.141 21.031 1.00 26.54 ? 462 GLY A C 1 ATOM 2964 O O . GLY A 1 391 ? 15.311 -136.915 21.571 1.00 22.36 ? 462 GLY A O 1 ATOM 2965 N N . GLN A 1 392 ? 13.775 -138.371 20.798 1.00 23.20 ? 463 GLN A N 1 ATOM 2966 C CA . GLN A 1 392 ? 14.553 -139.555 21.150 1.00 24.63 ? 463 GLN A CA 1 ATOM 2967 C C . GLN A 1 392 ? 14.701 -140.497 19.962 1.00 23.13 ? 463 GLN A C 1 ATOM 2968 O O . GLN A 1 392 ? 13.818 -140.584 19.104 1.00 25.31 ? 463 GLN A O 1 ATOM 2969 C CB . GLN A 1 392 ? 13.901 -140.294 22.323 1.00 28.98 ? 463 GLN A CB 1 ATOM 2970 C CG . GLN A 1 392 ? 13.823 -139.475 23.604 1.00 30.77 ? 463 GLN A CG 1 ATOM 2971 C CD . GLN A 1 392 ? 15.184 -139.244 24.235 1.00 45.86 ? 463 GLN A CD 1 ATOM 2972 O OE1 . GLN A 1 392 ? 15.879 -140.192 24.601 1.00 51.80 ? 463 GLN A OE1 1 ATOM 2973 N NE2 . GLN A 1 392 ? 15.572 -137.980 24.363 1.00 44.20 ? 463 GLN A NE2 1 ATOM 2974 N N . ILE A 1 393 ? 15.826 -141.204 19.926 1.00 19.51 ? 464 ILE A N 1 ATOM 2975 C CA . ILE A 1 393 ? 16.110 -142.140 18.851 1.00 24.12 ? 464 ILE A CA 1 ATOM 2976 C C . ILE A 1 393 ? 15.173 -143.343 18.920 1.00 28.82 ? 464 ILE A C 1 ATOM 2977 O O . ILE A 1 393 ? 15.101 -144.033 19.937 1.00 22.37 ? 464 ILE A O 1 ATOM 2978 C CB . ILE A 1 393 ? 17.575 -142.627 18.898 1.00 24.28 ? 464 ILE A CB 1 ATOM 2979 C CG1 . ILE A 1 393 ? 18.533 -141.444 18.733 1.00 35.52 ? 464 ILE A CG1 1 ATOM 2980 C CG2 . ILE A 1 393 ? 17.838 -143.666 17.801 1.00 22.69 ? 464 ILE A CG2 1 ATOM 2981 C CD1 . ILE A 1 393 ? 19.989 -141.779 19.013 1.00 44.50 ? 464 ILE A CD1 1 ATOM 2982 N N . GLN A 1 394 ? 14.443 -143.564 17.833 1.00 23.16 ? 465 GLN A N 1 ATOM 2983 C CA . GLN A 1 394 ? 13.648 -144.768 17.655 1.00 20.22 ? 465 GLN A CA 1 ATOM 2984 C C . GLN A 1 394 ? 14.398 -145.724 16.745 1.00 23.98 ? 465 GLN A C 1 ATOM 2985 O O . GLN A 1 394 ? 14.875 -145.336 15.674 1.00 23.39 ? 465 GLN A O 1 ATOM 2986 C CB . GLN A 1 394 ? 12.277 -144.446 17.065 1.00 25.40 ? 465 GLN A CB 1 ATOM 2987 C CG . GLN A 1 394 ? 11.515 -143.371 17.808 1.00 43.36 ? 465 GLN A CG 1 ATOM 2988 C CD . GLN A 1 394 ? 11.122 -143.784 19.216 1.00 64.17 ? 465 GLN A CD 1 ATOM 2989 O OE1 . GLN A 1 394 ? 10.383 -144.750 19.405 1.00 56.53 ? 465 GLN A OE1 1 ATOM 2990 N NE2 . GLN A 1 394 ? 11.613 -143.051 20.213 1.00 50.49 ? 465 GLN A NE2 1 ATOM 2991 N N . SER A 1 395 ? 14.500 -146.969 17.196 1.00 21.03 ? 466 SER A N 1 ATOM 2992 C CA . SER A 1 395 ? 15.156 -148.036 16.458 1.00 20.01 ? 466 SER A CA 1 ATOM 2993 C C . SER A 1 395 ? 14.223 -149.233 16.396 1.00 26.76 ? 466 SER A C 1 ATOM 2994 O O . SER A 1 395 ? 13.874 -149.806 17.430 1.00 20.09 ? 466 SER A O 1 ATOM 2995 C CB . SER A 1 395 ? 16.476 -148.421 17.125 1.00 16.05 ? 466 SER A CB 1 ATOM 2996 O OG . SER A 1 395 ? 17.005 -149.605 16.561 1.00 21.20 ? 466 SER A OG 1 ATOM 2997 N N . THR A 1 396 ? 13.805 -149.600 15.189 1.00 18.60 ? 467 THR A N 1 ATOM 2998 C CA . THR A 1 396 ? 12.880 -150.714 15.014 1.00 27.71 ? 467 THR A CA 1 ATOM 2999 C C . THR A 1 396 ? 13.221 -151.522 13.770 1.00 22.98 ? 467 THR A C 1 ATOM 3000 O O . THR A 1 396 ? 14.101 -151.145 13.001 1.00 22.07 ? 467 THR A O 1 ATOM 3001 C CB . THR A 1 396 ? 11.419 -150.225 14.906 1.00 30.83 ? 467 THR A CB 1 ATOM 3002 O OG1 . THR A 1 396 ? 11.278 -149.372 13.764 1.00 38.30 ? 467 THR A OG1 1 ATOM 3003 C CG2 . THR A 1 396 ? 11.009 -149.462 16.161 1.00 39.71 ? 467 THR A CG2 1 ATOM 3004 N N . SER A 1 397 ? 12.532 -152.646 13.599 1.00 24.42 ? 468 SER A N 1 ATOM 3005 C CA . SER A 1 397 ? 12.621 -153.436 12.378 1.00 28.11 ? 468 SER A CA 1 ATOM 3006 C C . SER A 1 397 ? 11.274 -153.418 11.671 1.00 38.14 ? 468 SER A C 1 ATOM 3007 O O . SER A 1 397 ? 10.235 -153.623 12.300 1.00 29.37 ? 468 SER A O 1 ATOM 3008 C CB . SER A 1 397 ? 13.046 -154.874 12.677 1.00 28.27 ? 468 SER A CB 1 ATOM 3009 O OG . SER A 1 397 ? 14.438 -154.950 12.934 1.00 35.76 ? 468 SER A OG 1 ATOM 3010 N N . VAL A 1 398 ? 11.297 -153.163 10.367 1.00 31.72 ? 469 VAL A N 1 ATOM 3011 C CA . VAL A 1 398 ? 10.070 -153.080 9.582 1.00 30.17 ? 469 VAL A CA 1 ATOM 3012 C C . VAL A 1 398 ? 10.202 -153.913 8.315 1.00 24.98 ? 469 VAL A C 1 ATOM 3013 O O . VAL A 1 398 ? 11.273 -154.447 8.022 1.00 28.63 ? 469 VAL A O 1 ATOM 3014 C CB . VAL A 1 398 ? 9.731 -151.618 9.212 1.00 32.77 ? 469 VAL A CB 1 ATOM 3015 C CG1 . VAL A 1 398 ? 9.584 -150.775 10.470 1.00 33.73 ? 469 VAL A CG1 1 ATOM 3016 C CG2 . VAL A 1 398 ? 10.797 -151.025 8.303 1.00 25.97 ? 469 VAL A CG2 1 ATOM 3017 N N . ASP A 1 399 ? 9.108 -154.018 7.568 1.00 37.98 ? 470 ASP A N 1 ATOM 3018 C CA . ASP A 1 399 ? 9.085 -154.810 6.344 1.00 36.77 ? 470 ASP A CA 1 ATOM 3019 C C . ASP A 1 399 ? 10.031 -154.246 5.293 1.00 31.51 ? 470 ASP A C 1 ATOM 3020 O O . ASP A 1 399 ? 10.210 -153.032 5.190 1.00 33.26 ? 470 ASP A O 1 ATOM 3021 C CB . ASP A 1 399 ? 7.667 -154.871 5.769 1.00 46.40 ? 470 ASP A CB 1 ATOM 3022 C CG . ASP A 1 399 ? 6.686 -155.569 6.693 1.00 73.23 ? 470 ASP A CG 1 ATOM 3023 O OD1 . ASP A 1 399 ? 7.120 -156.418 7.502 1.00 62.62 ? 470 ASP A OD1 1 ATOM 3024 O OD2 . ASP A 1 399 ? 5.476 -155.271 6.605 1.00 64.76 ? 470 ASP A OD2 1 ATOM 3025 N N . CYS A 1 400 ? 10.633 -155.136 4.512 1.00 31.91 ? 471 CYS A N 1 ATOM 3026 C CA . CYS A 1 400 ? 11.443 -154.725 3.375 1.00 44.61 ? 471 CYS A CA 1 ATOM 3027 C C . CYS A 1 400 ? 10.542 -154.156 2.287 1.00 37.16 ? 471 CYS A C 1 ATOM 3028 O O . CYS A 1 400 ? 9.321 -154.305 2.348 1.00 37.75 ? 471 CYS A O 1 ATOM 3029 C CB . CYS A 1 400 ? 12.251 -155.904 2.833 1.00 50.32 ? 471 CYS A CB 1 ATOM 3030 S SG . CYS A 1 400 ? 13.417 -156.615 4.018 1.00 57.92 ? 471 CYS A SG 1 ATOM 3031 N N . THR A 1 401 ? 11.138 -153.498 1.297 1.00 37.86 ? 472 THR A N 1 ATOM 3032 C CA . THR A 1 401 ? 10.373 -153.006 0.157 1.00 50.07 ? 472 THR A CA 1 ATOM 3033 C C . THR A 1 401 ? 9.733 -154.180 -0.576 1.00 46.03 ? 472 THR A C 1 ATOM 3034 O O . THR A 1 401 ? 10.217 -155.310 -0.487 1.00 42.13 ? 472 THR A O 1 ATOM 3035 C CB . THR A 1 401 ? 11.252 -152.213 -0.830 1.00 44.89 ? 472 THR A CB 1 ATOM 3036 O OG1 . THR A 1 401 ? 12.305 -153.053 -1.318 1.00 44.24 ? 472 THR A OG1 1 ATOM 3037 C CG2 . THR A 1 401 ? 11.851 -150.987 -0.157 1.00 47.65 ? 472 THR A CG2 1 ATOM 3038 N N . ALA A 1 402 ? 8.639 -153.914 -1.285 1.00 50.99 ? 473 ALA A N 1 ATOM 3039 C CA . ALA A 1 402 ? 7.977 -154.939 -2.087 1.00 53.16 ? 473 ALA A CA 1 ATOM 3040 C C . ALA A 1 402 ? 8.969 -155.554 -3.065 1.00 49.73 ? 473 ALA A C 1 ATOM 3041 O O . ALA A 1 402 ? 8.959 -156.762 -3.305 1.00 57.25 ? 473 ALA A O 1 ATOM 3042 C CB . ALA A 1 402 ? 6.785 -154.350 -2.831 1.00 46.84 ? 473 ALA A CB 1 ATOM 3043 N N . ASP A 1 403 ? 9.829 -154.707 -3.620 1.00 44.75 ? 474 ASP A N 1 ATOM 3044 C CA . ASP A 1 403 ? 10.896 -155.151 -4.508 1.00 57.29 ? 474 ASP A CA 1 ATOM 3045 C C . ASP A 1 403 ? 11.832 -156.137 -3.809 1.00 70.67 ? 474 ASP A C 1 ATOM 3046 O O . ASP A 1 403 ? 12.179 -157.180 -4.364 1.00 70.03 ? 474 ASP A O 1 ATOM 3047 C CB . ASP A 1 403 ? 11.689 -153.945 -5.013 1.00 61.97 ? 474 ASP A CB 1 ATOM 3048 C CG . ASP A 1 403 ? 12.911 -154.345 -5.813 1.00 72.98 ? 474 ASP A CG 1 ATOM 3049 O OD1 . ASP A 1 403 ? 12.774 -154.585 -7.031 1.00 82.44 ? 474 ASP A OD1 1 ATOM 3050 O OD2 . ASP A 1 403 ? 14.009 -154.416 -5.222 1.00 81.39 ? 474 ASP A OD2 1 ATOM 3051 N N . GLU A 1 404 ? 12.232 -155.796 -2.587 1.00 70.79 ? 475 GLU A N 1 ATOM 3052 C CA . GLU A 1 404 ? 13.167 -156.611 -1.814 1.00 66.32 ? 475 GLU A CA 1 ATOM 3053 C C . GLU A 1 404 ? 12.556 -157.938 -1.362 1.00 59.10 ? 475 GLU A C 1 ATOM 3054 O O . GLU A 1 404 ? 13.274 -158.915 -1.150 1.00 60.70 ? 475 GLU A O 1 ATOM 3055 C CB . GLU A 1 404 ? 13.658 -155.828 -0.588 1.00 69.03 ? 475 GLU A CB 1 ATOM 3056 C CG . GLU A 1 404 ? 14.762 -154.811 -0.888 1.00 75.57 ? 475 GLU A CG 1 ATOM 3057 C CD . GLU A 1 404 ? 15.103 -153.920 0.300 1.00 70.97 ? 475 GLU A CD 1 ATOM 3058 O OE1 . GLU A 1 404 ? 16.279 -153.511 0.415 1.00 77.71 ? 475 GLU A OE1 1 ATOM 3059 O OE2 . GLU A 1 404 ? 14.205 -153.626 1.119 1.00 45.36 ? 475 GLU A OE2 1 ATOM 3060 N N . GLN A 1 405 ? 11.235 -157.971 -1.216 1.00 52.72 ? 476 GLN A N 1 ATOM 3061 C CA . GLN A 1 405 ? 10.556 -159.151 -0.687 1.00 59.00 ? 476 GLN A CA 1 ATOM 3062 C C . GLN A 1 405 ? 10.653 -160.363 -1.614 1.00 69.81 ? 476 GLN A C 1 ATOM 3063 O O . GLN A 1 405 ? 10.401 -161.492 -1.190 1.00 66.94 ? 476 GLN A O 1 ATOM 3064 C CB . GLN A 1 405 ? 9.087 -158.832 -0.406 1.00 49.06 ? 476 GLN A CB 1 ATOM 3065 C CG . GLN A 1 405 ? 8.850 -158.252 0.979 1.00 48.62 ? 476 GLN A CG 1 ATOM 3066 C CD . GLN A 1 405 ? 7.427 -157.774 1.185 1.00 53.82 ? 476 GLN A CD 1 ATOM 3067 O OE1 . GLN A 1 405 ? 7.194 -156.726 1.788 1.00 61.19 ? 476 GLN A OE1 1 ATOM 3068 N NE2 . GLN A 1 405 ? 6.464 -158.545 0.693 1.00 62.47 ? 476 GLN A NE2 1 ATOM 3069 N N . ASN A 1 406 ? 11.019 -160.135 -2.871 1.00 73.26 ? 477 ASN A N 1 ATOM 3070 C CA . ASN A 1 406 ? 11.205 -161.231 -3.814 1.00 84.25 ? 477 ASN A CA 1 ATOM 3071 C C . ASN A 1 406 ? 12.435 -162.060 -3.457 1.00 81.06 ? 477 ASN A C 1 ATOM 3072 O O . ASN A 1 406 ? 12.477 -163.265 -3.702 1.00 77.03 ? 477 ASN A O 1 ATOM 3073 C CB . ASN A 1 406 ? 11.336 -160.699 -5.241 1.00 90.12 ? 477 ASN A CB 1 ATOM 3074 C CG . ASN A 1 406 ? 10.141 -159.875 -5.669 1.00 94.62 ? 477 ASN A CG 1 ATOM 3075 O OD1 . ASN A 1 406 ? 9.047 -160.011 -5.120 1.00 83.90 ? 477 ASN A OD1 1 ATOM 3076 N ND2 . ASN A 1 406 ? 10.342 -159.013 -6.660 1.00 86.52 ? 477 ASN A ND2 1 ATOM 3077 N N . GLU A 1 407 ? 13.427 -161.401 -2.866 1.00 82.91 ? 478 GLU A N 1 ATOM 3078 C CA . GLU A 1 407 ? 14.700 -162.035 -2.546 1.00 76.66 ? 478 GLU A CA 1 ATOM 3079 C C . GLU A 1 407 ? 14.580 -162.852 -1.262 1.00 74.58 ? 478 GLU A C 1 ATOM 3080 O O . GLU A 1 407 ? 15.458 -163.656 -0.941 1.00 70.46 ? 478 GLU A O 1 ATOM 3081 C CB . GLU A 1 407 ? 15.819 -160.995 -2.380 1.00 79.78 ? 478 GLU A CB 1 ATOM 3082 C CG . GLU A 1 407 ? 15.689 -159.704 -3.215 1.00 90.02 ? 478 GLU A CG 1 ATOM 3083 C CD . GLU A 1 407 ? 16.500 -158.547 -2.650 1.00 109.08 ? 478 GLU A CD 1 ATOM 3084 O OE1 . GLU A 1 407 ? 16.724 -158.506 -1.420 1.00 88.10 ? 478 GLU A OE1 1 ATOM 3085 O OE2 . GLU A 1 407 ? 16.917 -157.669 -3.437 1.00 114.41 ? 478 GLU A OE2 1 ATOM 3086 N N . CYS A 1 408 ? 13.493 -162.636 -0.526 1.00 70.23 ? 479 CYS A N 1 ATOM 3087 C CA . CYS A 1 408 ? 13.296 -163.283 0.766 1.00 75.22 ? 479 CYS A CA 1 ATOM 3088 C C . CYS A 1 408 ? 12.977 -164.764 0.594 1.00 73.06 ? 479 CYS A C 1 ATOM 3089 O O . CYS A 1 408 ? 11.865 -165.208 0.880 1.00 72.59 ? 479 CYS A O 1 ATOM 3090 C CB . CYS A 1 408 ? 12.173 -162.590 1.545 1.00 92.25 ? 479 CYS A CB 1 ATOM 3091 S SG . CYS A 1 408 ? 12.545 -160.896 2.083 1.00 74.50 ? 479 CYS A SG 1 ATOM 3092 N N . SER B 1 10 ? 1.037 -97.255 53.504 1.00 66.21 ? 68 SER C N 1 ATOM 3093 C CA . SER B 1 10 ? 2.346 -96.733 53.877 1.00 85.53 ? 68 SER C CA 1 ATOM 3094 C C . SER B 1 10 ? 2.668 -97.073 55.330 1.00 110.74 ? 68 SER C C 1 ATOM 3095 O O . SER B 1 10 ? 1.826 -97.608 56.054 1.00 104.43 ? 68 SER C O 1 ATOM 3096 C CB . SER B 1 10 ? 2.402 -95.221 53.654 1.00 86.26 ? 68 SER C CB 1 ATOM 3097 O OG . SER B 1 10 ? 2.063 -94.901 52.315 1.00 75.38 ? 68 SER C OG 1 ATOM 3098 N N . GLY B 1 11 ? 3.890 -96.754 55.747 1.00 106.73 ? 69 GLY C N 1 ATOM 3099 C CA . GLY B 1 11 ? 4.393 -97.142 57.052 1.00 71.97 ? 69 GLY C CA 1 ATOM 3100 C C . GLY B 1 11 ? 5.301 -98.347 56.904 1.00 59.40 ? 69 GLY C C 1 ATOM 3101 O O . GLY B 1 11 ? 5.263 -99.279 57.705 1.00 57.91 ? 69 GLY C O 1 ATOM 3102 N N . ASN B 1 12 ? 6.118 -98.321 55.856 1.00 64.77 ? 70 ASN C N 1 ATOM 3103 C CA . ASN B 1 12 ? 7.038 -99.412 55.557 1.00 50.10 ? 70 ASN C CA 1 ATOM 3104 C C . ASN B 1 12 ? 8.155 -99.477 56.599 1.00 40.06 ? 70 ASN C C 1 ATOM 3105 O O . ASN B 1 12 ? 8.993 -98.578 56.658 1.00 44.47 ? 70 ASN C O 1 ATOM 3106 C CB . ASN B 1 12 ? 7.619 -99.231 54.151 1.00 40.92 ? 70 ASN C CB 1 ATOM 3107 C CG . ASN B 1 12 ? 8.489 -100.397 53.713 1.00 42.36 ? 70 ASN C CG 1 ATOM 3108 O OD1 . ASN B 1 12 ? 8.663 -101.374 54.441 1.00 40.02 ? 70 ASN C OD1 1 ATOM 3109 N ND2 . ASN B 1 12 ? 9.032 -100.300 52.506 1.00 43.72 ? 70 ASN C ND2 1 ATOM 3110 N N . PRO B 1 13 ? 8.176 -100.540 57.425 1.00 35.84 ? 71 PRO C N 1 ATOM 3111 C CA . PRO B 1 13 ? 9.172 -100.596 58.503 1.00 43.37 ? 71 PRO C CA 1 ATOM 3112 C C . PRO B 1 13 ? 10.607 -100.670 57.993 1.00 43.91 ? 71 PRO C C 1 ATOM 3113 O O . PRO B 1 13 ? 11.534 -100.341 58.734 1.00 40.21 ? 71 PRO C O 1 ATOM 3114 C CB . PRO B 1 13 ? 8.798 -101.875 59.262 1.00 38.93 ? 71 PRO C CB 1 ATOM 3115 C CG . PRO B 1 13 ? 8.082 -102.710 58.272 1.00 40.80 ? 71 PRO C CG 1 ATOM 3116 C CD . PRO B 1 13 ? 7.344 -101.756 57.385 1.00 43.06 ? 71 PRO C CD 1 ATOM 3117 N N . PHE B 1 14 ? 10.787 -101.087 56.745 1.00 41.63 ? 72 PHE C N 1 ATOM 3118 C CA . PHE B 1 14 ? 12.122 -101.209 56.174 1.00 34.15 ? 72 PHE C CA 1 ATOM 3119 C C . PHE B 1 14 ? 12.552 -99.914 55.482 1.00 38.25 ? 72 PHE C C 1 ATOM 3120 O O . PHE B 1 14 ? 13.578 -99.874 54.803 1.00 47.78 ? 72 PHE C O 1 ATOM 3121 C CB . PHE B 1 14 ? 12.171 -102.393 55.209 1.00 34.36 ? 72 PHE C CB 1 ATOM 3122 C CG . PHE B 1 14 ? 11.822 -103.699 55.858 1.00 32.32 ? 72 PHE C CG 1 ATOM 3123 C CD1 . PHE B 1 14 ? 12.781 -104.425 56.544 1.00 30.11 ? 72 PHE C CD1 1 ATOM 3124 C CD2 . PHE B 1 14 ? 10.530 -104.190 55.802 1.00 27.35 ? 72 PHE C CD2 1 ATOM 3125 C CE1 . PHE B 1 14 ? 12.458 -105.623 57.153 1.00 33.33 ? 72 PHE C CE1 1 ATOM 3126 C CE2 . PHE B 1 14 ? 10.202 -105.385 56.407 1.00 30.41 ? 72 PHE C CE2 1 ATOM 3127 C CZ . PHE B 1 14 ? 11.166 -106.103 57.084 1.00 29.88 ? 72 PHE C CZ 1 ATOM 3128 N N . GLN B 1 15 ? 11.757 -98.862 55.664 1.00 41.88 ? 73 GLN C N 1 ATOM 3129 C CA . GLN B 1 15 ? 12.120 -97.510 55.240 1.00 54.36 ? 73 GLN C CA 1 ATOM 3130 C C . GLN B 1 15 ? 11.931 -96.551 56.412 1.00 56.39 ? 73 GLN C C 1 ATOM 3131 O O . GLN B 1 15 ? 11.834 -95.337 56.231 1.00 55.84 ? 73 GLN C O 1 ATOM 3132 C CB . GLN B 1 15 ? 11.272 -97.061 54.046 1.00 45.54 ? 73 GLN C CB 1 ATOM 3133 C CG . GLN B 1 15 ? 11.432 -97.919 52.800 1.00 49.39 ? 73 GLN C CG 1 ATOM 3134 C CD . GLN B 1 15 ? 12.821 -97.824 52.198 1.00 55.56 ? 73 GLN C CD 1 ATOM 3135 O OE1 . GLN B 1 15 ? 13.353 -96.731 52.007 1.00 62.00 ? 73 GLN C OE1 1 ATOM 3136 N NE2 . GLN B 1 15 ? 13.418 -98.973 51.897 1.00 52.83 ? 73 GLN C NE2 1 ATOM 3137 N N . ALA B 1 16 ? 11.894 -97.111 57.618 1.00 59.77 ? 74 ALA C N 1 ATOM 3138 C CA . ALA B 1 16 ? 11.501 -96.369 58.810 1.00 57.86 ? 74 ALA C CA 1 ATOM 3139 C C . ALA B 1 16 ? 12.536 -95.329 59.236 1.00 63.84 ? 74 ALA C C 1 ATOM 3140 O O . ALA B 1 16 ? 12.176 -94.284 59.776 1.00 72.25 ? 74 ALA C O 1 ATOM 3141 C CB . ALA B 1 16 ? 11.232 -97.338 59.954 1.00 54.48 ? 74 ALA C CB 1 ATOM 3142 N N . ASN B 1 17 ? 13.814 -95.613 58.999 1.00 65.30 ? 75 ASN C N 1 ATOM 3143 C CA . ASN B 1 17 ? 14.877 -94.695 59.396 1.00 59.91 ? 75 ASN C CA 1 ATOM 3144 C C . ASN B 1 17 ? 16.119 -94.808 58.514 1.00 61.72 ? 75 ASN C C 1 ATOM 3145 O O . ASN B 1 17 ? 16.155 -95.595 57.568 1.00 59.02 ? 75 ASN C O 1 ATOM 3146 C CB . ASN B 1 17 ? 15.255 -94.931 60.861 1.00 57.96 ? 75 ASN C CB 1 ATOM 3147 C CG . ASN B 1 17 ? 15.687 -96.358 61.129 1.00 59.51 ? 75 ASN C CG 1 ATOM 3148 O OD1 . ASN B 1 17 ? 16.776 -96.776 60.736 1.00 57.28 ? 75 ASN C OD1 1 ATOM 3149 N ND2 . ASN B 1 17 ? 14.836 -97.113 61.815 1.00 53.02 ? 75 ASN C ND2 1 ATOM 3150 N N . VAL B 1 18 ? 17.133 -94.013 58.843 1.00 58.51 ? 76 VAL C N 1 ATOM 3151 C CA . VAL B 1 18 ? 18.337 -93.892 58.026 1.00 65.84 ? 76 VAL C CA 1 ATOM 3152 C C . VAL B 1 18 ? 19.134 -95.194 57.971 1.00 63.03 ? 76 VAL C C 1 ATOM 3153 O O . VAL B 1 18 ? 19.561 -95.619 56.899 1.00 57.68 ? 76 VAL C O 1 ATOM 3154 C CB . VAL B 1 18 ? 19.242 -92.756 58.559 1.00 62.63 ? 76 VAL C CB 1 ATOM 3155 C CG1 . VAL B 1 18 ? 20.537 -92.652 57.756 1.00 58.61 ? 76 VAL C CG1 1 ATOM 3156 C CG2 . VAL B 1 18 ? 18.491 -91.430 58.527 1.00 58.71 ? 76 VAL C CG2 1 ATOM 3157 N N . GLU B 1 19 ? 19.337 -95.814 59.129 1.00 50.72 ? 77 GLU C N 1 ATOM 3158 C CA . GLU B 1 19 ? 20.071 -97.074 59.219 1.00 58.09 ? 77 GLU C CA 1 ATOM 3159 C C . GLU B 1 19 ? 19.410 -98.150 58.357 1.00 57.51 ? 77 GLU C C 1 ATOM 3160 O O . GLU B 1 19 ? 20.067 -98.837 57.566 1.00 54.43 ? 77 GLU C O 1 ATOM 3161 C CB . GLU B 1 19 ? 20.147 -97.529 60.681 1.00 67.42 ? 77 GLU C CB 1 ATOM 3162 C CG . GLU B 1 19 ? 20.975 -98.785 60.925 1.00 85.34 ? 77 GLU C CG 1 ATOM 3163 C CD . GLU B 1 19 ? 21.070 -99.146 62.399 1.00 96.59 ? 77 GLU C CD 1 ATOM 3164 O OE1 . GLU B 1 19 ? 20.683 -98.313 63.247 1.00 97.34 ? 77 GLU C OE1 1 ATOM 3165 O OE2 . GLU B 1 19 ? 21.530 -100.265 62.711 1.00 80.37 ? 77 GLU C OE2 1 ATOM 3166 N N . MET B 1 20 ? 18.096 -98.274 58.510 1.00 51.03 ? 78 MET C N 1 ATOM 3167 C CA . MET B 1 20 ? 17.313 -99.268 57.789 1.00 51.93 ? 78 MET C CA 1 ATOM 3168 C C . MET B 1 20 ? 17.332 -99.006 56.284 1.00 43.61 ? 78 MET C C 1 ATOM 3169 O O . MET B 1 20 ? 17.549 -99.921 55.487 1.00 42.15 ? 78 MET C O 1 ATOM 3170 C CB . MET B 1 20 ? 15.876 -99.267 58.308 1.00 46.78 ? 78 MET C CB 1 ATOM 3171 C CG . MET B 1 20 ? 15.004 -100.358 57.736 1.00 54.11 ? 78 MET C CG 1 ATOM 3172 S SD . MET B 1 20 ? 15.508 -102.008 58.255 1.00 53.53 ? 78 MET C SD 1 ATOM 3173 C CE . MET B 1 20 ? 14.760 -102.101 59.881 1.00 42.47 ? 78 MET C CE 1 ATOM 3174 N N . LYS B 1 21 ? 17.090 -97.754 55.905 1.00 41.75 ? 79 LYS C N 1 ATOM 3175 C CA . LYS B 1 21 ? 17.178 -97.337 54.508 1.00 45.90 ? 79 LYS C CA 1 ATOM 3176 C C . LYS B 1 21 ? 18.540 -97.701 53.935 1.00 43.72 ? 79 LYS C C 1 ATOM 3177 O O . LYS B 1 21 ? 18.640 -98.283 52.854 1.00 44.93 ? 79 LYS C O 1 ATOM 3178 C CB . LYS B 1 21 ? 16.949 -95.831 54.374 1.00 53.42 ? 79 LYS C CB 1 ATOM 3179 C CG . LYS B 1 21 ? 15.494 -95.396 54.413 1.00 52.94 ? 79 LYS C CG 1 ATOM 3180 C CD . LYS B 1 21 ? 15.387 -93.879 54.340 1.00 61.45 ? 79 LYS C CD 1 ATOM 3181 C CE . LYS B 1 21 ? 14.105 -93.427 53.661 1.00 83.83 ? 79 LYS C CE 1 ATOM 3182 N NZ . LYS B 1 21 ? 14.131 -91.967 53.363 1.00 83.52 ? 79 LYS C NZ 1 ATOM 3183 N N . THR B 1 22 ? 19.585 -97.344 54.674 1.00 43.35 ? 80 THR C N 1 ATOM 3184 C CA . THR B 1 22 ? 20.953 -97.660 54.294 1.00 45.99 ? 80 THR C CA 1 ATOM 3185 C C . THR B 1 22 ? 21.112 -99.158 54.087 1.00 42.67 ? 80 THR C C 1 ATOM 3186 O O . THR B 1 22 ? 21.710 -99.590 53.101 1.00 44.62 ? 80 THR C O 1 ATOM 3187 C CB . THR B 1 22 ? 21.959 -97.177 55.359 1.00 45.72 ? 80 THR C CB 1 ATOM 3188 O OG1 . THR B 1 22 ? 21.968 -95.745 55.396 1.00 52.35 ? 80 THR C OG1 1 ATOM 3189 C CG2 . THR B 1 22 ? 23.369 -97.677 55.055 1.00 46.36 ? 80 THR C CG2 1 ATOM 3190 N N . PHE B 1 23 ? 20.586 -99.948 55.019 1.00 37.93 ? 81 PHE C N 1 ATOM 3191 C CA . PHE B 1 23 ? 20.625 -101.399 54.867 1.00 37.31 ? 81 PHE C CA 1 ATOM 3192 C C . PHE B 1 23 ? 19.924 -101.863 53.593 1.00 41.75 ? 81 PHE C C 1 ATOM 3193 O O . PHE B 1 23 ? 20.493 -102.624 52.814 1.00 38.54 ? 81 PHE C O 1 ATOM 3194 C CB . PHE B 1 23 ? 19.993 -102.103 56.072 1.00 38.29 ? 81 PHE C CB 1 ATOM 3195 C CG . PHE B 1 23 ? 19.912 -103.597 55.916 1.00 31.65 ? 81 PHE C CG 1 ATOM 3196 C CD1 . PHE B 1 23 ? 21.062 -104.368 55.929 1.00 37.59 ? 81 PHE C CD1 1 ATOM 3197 C CD2 . PHE B 1 23 ? 18.690 -104.228 55.744 1.00 34.34 ? 81 PHE C CD2 1 ATOM 3198 C CE1 . PHE B 1 23 ? 20.997 -105.742 55.778 1.00 41.92 ? 81 PHE C CE1 1 ATOM 3199 C CE2 . PHE B 1 23 ? 18.619 -105.603 55.592 1.00 28.52 ? 81 PHE C CE2 1 ATOM 3200 C CZ . PHE B 1 23 ? 19.775 -106.360 55.609 1.00 33.62 ? 81 PHE C CZ 1 ATOM 3201 N N . MET B 1 24 ? 18.691 -101.414 53.382 1.00 36.31 ? 82 MET C N 1 ATOM 3202 C CA . MET B 1 24 ? 17.908 -101.888 52.243 1.00 30.68 ? 82 MET C CA 1 ATOM 3203 C C . MET B 1 24 ? 18.435 -101.405 50.892 1.00 39.40 ? 82 MET C C 1 ATOM 3204 O O . MET B 1 24 ? 18.318 -102.114 49.893 1.00 33.35 ? 82 MET C O 1 ATOM 3205 C CB . MET B 1 24 ? 16.444 -101.465 52.391 1.00 30.20 ? 82 MET C CB 1 ATOM 3206 C CG . MET B 1 24 ? 15.688 -102.216 53.479 1.00 43.42 ? 82 MET C CG 1 ATOM 3207 S SD . MET B 1 24 ? 15.642 -104.006 53.228 1.00 43.35 ? 82 MET C SD 1 ATOM 3208 C CE . MET B 1 24 ? 14.700 -104.128 51.710 1.00 44.87 ? 82 MET C CE 1 ATOM 3209 N N . GLU B 1 25 ? 19.007 -100.207 50.849 1.00 33.31 ? 83 GLU C N 1 ATOM 3210 C CA . GLU B 1 25 ? 19.521 -99.671 49.591 1.00 40.70 ? 83 GLU C CA 1 ATOM 3211 C C . GLU B 1 25 ? 20.667 -100.510 49.023 1.00 33.38 ? 83 GLU C C 1 ATOM 3212 O O . GLU B 1 25 ? 20.989 -100.409 47.840 1.00 33.73 ? 83 GLU C O 1 ATOM 3213 C CB . GLU B 1 25 ? 19.982 -98.223 49.772 1.00 40.48 ? 83 GLU C CB 1 ATOM 3214 C CG . GLU B 1 25 ? 19.029 -97.203 49.167 1.00 59.46 ? 83 GLU C CG 1 ATOM 3215 C CD . GLU B 1 25 ? 18.933 -97.319 47.657 1.00 76.52 ? 83 GLU C CD 1 ATOM 3216 O OE1 . GLU B 1 25 ? 19.991 -97.423 47.000 1.00 76.98 ? 83 GLU C OE1 1 ATOM 3217 O OE2 . GLU B 1 25 ? 17.802 -97.317 47.127 1.00 64.79 ? 83 GLU C OE2 1 ATOM 3218 N N . ARG B 1 26 ? 21.259 -101.347 49.849 1.00 30.35 ? 84 ARG C N 1 ATOM 3219 C CA . ARG B 1 26 ? 22.352 -102.194 49.427 1.00 30.00 ? 84 ARG C CA 1 ATOM 3220 C C . ARG B 1 26 ? 21.900 -103.200 48.371 1.00 28.69 ? 84 ARG C C 1 ATOM 3221 O O . ARG B 1 26 ? 22.701 -103.785 47.694 1.00 33.31 ? 84 ARG C O 1 ATOM 3222 C CB . ARG B 1 26 ? 22.998 -102.895 50.635 1.00 30.94 ? 84 ARG C CB 1 ATOM 3223 C CG . ARG B 1 26 ? 22.597 -104.340 50.878 1.00 48.71 ? 84 ARG C CG 1 ATOM 3224 C CD . ARG B 1 26 ? 22.757 -104.766 52.322 1.00 50.34 ? 84 ARG C CD 1 ATOM 3225 N NE . ARG B 1 26 ? 23.944 -104.201 52.927 1.00 61.80 ? 84 ARG C NE 1 ATOM 3226 C CZ . ARG B 1 26 ? 25.129 -104.794 52.932 1.00 75.39 ? 84 ARG C CZ 1 ATOM 3227 N NH1 . ARG B 1 26 ? 26.155 -104.204 53.513 1.00 78.18 ? 84 ARG C NH1 1 ATOM 3228 N NH2 . ARG B 1 26 ? 25.285 -105.979 52.370 1.00 56.88 ? 84 ARG C NH2 1 ATOM 3229 N N . PHE B 1 27 ? 20.607 -103.428 48.284 1.00 25.92 ? 85 PHE C N 1 ATOM 3230 C CA . PHE B 1 27 ? 20.048 -104.410 47.361 1.00 30.95 ? 85 PHE C CA 1 ATOM 3231 C C . PHE B 1 27 ? 19.633 -103.789 46.032 1.00 29.12 ? 85 PHE C C 1 ATOM 3232 O O . PHE B 1 27 ? 19.209 -104.499 45.126 1.00 31.98 ? 85 PHE C O 1 ATOM 3233 C CB . PHE B 1 27 ? 18.844 -105.111 47.993 1.00 28.85 ? 85 PHE C CB 1 ATOM 3234 C CG . PHE B 1 27 ? 19.182 -105.899 49.222 1.00 29.64 ? 85 PHE C CG 1 ATOM 3235 C CD1 . PHE B 1 27 ? 19.928 -107.061 49.129 1.00 25.95 ? 85 PHE C CD1 1 ATOM 3236 C CD2 . PHE B 1 27 ? 18.747 -105.485 50.468 1.00 30.94 ? 85 PHE C CD2 1 ATOM 3237 C CE1 . PHE B 1 27 ? 20.242 -107.791 50.258 1.00 30.13 ? 85 PHE C CE1 1 ATOM 3238 C CE2 . PHE B 1 27 ? 19.056 -106.212 51.601 1.00 28.74 ? 85 PHE C CE2 1 ATOM 3239 C CZ . PHE B 1 27 ? 19.804 -107.367 51.496 1.00 32.67 ? 85 PHE C CZ 1 ATOM 3240 N N . ASN B 1 28 ? 19.746 -102.471 45.910 1.00 25.84 ? 86 ASN C N 1 ATOM 3241 C CA . ASN B 1 28 ? 19.421 -101.812 44.650 1.00 23.27 ? 86 ASN C CA 1 ATOM 3242 C C . ASN B 1 28 ? 20.645 -101.767 43.735 1.00 29.67 ? 86 ASN C C 1 ATOM 3243 O O . ASN B 1 28 ? 21.469 -100.858 43.824 1.00 23.23 ? 86 ASN C O 1 ATOM 3244 C CB . ASN B 1 28 ? 18.882 -100.402 44.902 1.00 26.67 ? 86 ASN C CB 1 ATOM 3245 C CG . ASN B 1 28 ? 18.304 -99.765 43.649 1.00 27.98 ? 86 ASN C CG 1 ATOM 3246 O OD1 . ASN B 1 28 ? 18.625 -100.165 42.529 1.00 27.33 ? 86 ASN C OD1 1 ATOM 3247 N ND2 . ASN B 1 28 ? 17.445 -98.766 43.833 1.00 31.54 ? 86 ASN C ND2 1 ATOM 3248 N N . LEU B 1 29 ? 20.752 -102.755 42.851 1.00 21.82 ? 87 LEU C N 1 ATOM 3249 C CA . LEU B 1 29 ? 21.893 -102.856 41.947 1.00 23.18 ? 87 LEU C CA 1 ATOM 3250 C C . LEU B 1 29 ? 21.816 -101.834 40.816 1.00 28.11 ? 87 LEU C C 1 ATOM 3251 O O . LEU B 1 29 ? 22.814 -101.562 40.151 1.00 25.20 ? 87 LEU C O 1 ATOM 3252 C CB . LEU B 1 29 ? 21.989 -104.271 41.375 1.00 15.21 ? 87 LEU C CB 1 ATOM 3253 C CG . LEU B 1 29 ? 22.364 -105.338 42.405 1.00 23.43 ? 87 LEU C CG 1 ATOM 3254 C CD1 . LEU B 1 29 ? 22.031 -106.725 41.892 1.00 24.83 ? 87 LEU C CD1 1 ATOM 3255 C CD2 . LEU B 1 29 ? 23.842 -105.243 42.760 1.00 27.59 ? 87 LEU C CD2 1 ATOM 3256 N N . THR B 1 30 ? 20.636 -101.266 40.598 1.00 23.28 ? 88 THR C N 1 ATOM 3257 C CA . THR B 1 30 ? 20.488 -100.206 39.612 1.00 27.97 ? 88 THR C CA 1 ATOM 3258 C C . THR B 1 30 ? 21.193 -98.952 40.111 1.00 38.04 ? 88 THR C C 1 ATOM 3259 O O . THR B 1 30 ? 21.789 -98.208 39.333 1.00 34.63 ? 88 THR C O 1 ATOM 3260 C CB . THR B 1 30 ? 19.009 -99.883 39.331 1.00 29.21 ? 88 THR C CB 1 ATOM 3261 O OG1 . THR B 1 30 ? 18.329 -101.069 38.902 1.00 31.88 ? 88 THR C OG1 1 ATOM 3262 C CG2 . THR B 1 30 ? 18.885 -98.816 38.256 1.00 34.57 ? 88 THR C CG2 1 ATOM 3263 N N . HIS B 1 31 ? 21.124 -98.730 41.419 1.00 30.25 ? 89 HIS C N 1 ATOM 3264 C CA . HIS B 1 31 ? 21.676 -97.526 42.024 1.00 37.14 ? 89 HIS C CA 1 ATOM 3265 C C . HIS B 1 31 ? 23.177 -97.635 42.256 1.00 32.13 ? 89 HIS C C 1 ATOM 3266 O O . HIS B 1 31 ? 23.923 -96.702 41.963 1.00 40.30 ? 89 HIS C O 1 ATOM 3267 C CB . HIS B 1 31 ? 20.979 -97.233 43.354 1.00 39.54 ? 89 HIS C CB 1 ATOM 3268 C CG . HIS B 1 31 ? 21.352 -95.913 43.953 1.00 50.76 ? 89 HIS C CG 1 ATOM 3269 N ND1 . HIS B 1 31 ? 21.291 -95.667 45.308 1.00 59.60 ? 89 HIS C ND1 1 ATOM 3270 C CD2 . HIS B 1 31 ? 21.787 -94.766 43.382 1.00 52.34 ? 89 HIS C CD2 1 ATOM 3271 C CE1 . HIS B 1 31 ? 21.675 -94.426 45.545 1.00 61.01 ? 89 HIS C CE1 1 ATOM 3272 N NE2 . HIS B 1 31 ? 21.982 -93.857 44.393 1.00 62.25 ? 89 HIS C NE2 1 ATOM 3273 N N . HIS B 1 32 ? 23.614 -98.777 42.777 1.00 25.97 ? 90 HIS C N 1 ATOM 3274 C CA . HIS B 1 32 ? 24.983 -98.919 43.264 1.00 34.17 ? 90 HIS C CA 1 ATOM 3275 C C . HIS B 1 32 ? 25.932 -99.593 42.272 1.00 36.69 ? 90 HIS C C 1 ATOM 3276 O O . HIS B 1 32 ? 27.087 -99.193 42.163 1.00 46.17 ? 90 HIS C O 1 ATOM 3277 C CB . HIS B 1 32 ? 24.979 -99.691 44.583 1.00 45.15 ? 90 HIS C CB 1 ATOM 3278 C CG . HIS B 1 32 ? 24.446 -98.901 45.739 1.00 59.30 ? 90 HIS C CG 1 ATOM 3279 N ND1 . HIS B 1 32 ? 23.767 -99.479 46.789 1.00 45.79 ? 90 HIS C ND1 1 ATOM 3280 C CD2 . HIS B 1 32 ? 24.497 -97.574 46.009 1.00 54.49 ? 90 HIS C CD2 1 ATOM 3281 C CE1 . HIS B 1 32 ? 23.421 -98.543 47.656 1.00 53.36 ? 90 HIS C CE1 1 ATOM 3282 N NE2 . HIS B 1 32 ? 23.852 -97.378 47.206 1.00 58.93 ? 90 HIS C NE2 1 ATOM 3283 N N . HIS B 1 33 ? 25.456 -100.606 41.556 1.00 28.89 ? 91 HIS C N 1 ATOM 3284 C CA . HIS B 1 33 ? 26.300 -101.307 40.588 1.00 24.79 ? 91 HIS C CA 1 ATOM 3285 C C . HIS B 1 33 ? 26.305 -100.574 39.245 1.00 20.46 ? 91 HIS C C 1 ATOM 3286 O O . HIS B 1 33 ? 27.362 -100.369 38.650 1.00 20.07 ? 91 HIS C O 1 ATOM 3287 C CB . HIS B 1 33 ? 25.829 -102.750 40.417 1.00 18.07 ? 91 HIS C CB 1 ATOM 3288 C CG . HIS B 1 33 ? 26.658 -103.549 39.463 1.00 23.75 ? 91 HIS C CG 1 ATOM 3289 N ND1 . HIS B 1 33 ? 27.929 -103.990 39.763 1.00 18.52 ? 91 HIS C ND1 1 ATOM 3290 C CD2 . HIS B 1 33 ? 26.392 -103.991 38.213 1.00 18.86 ? 91 HIS C CD2 1 ATOM 3291 C CE1 . HIS B 1 33 ? 28.409 -104.670 38.738 1.00 24.76 ? 91 HIS C CE1 1 ATOM 3292 N NE2 . HIS B 1 33 ? 27.497 -104.683 37.783 1.00 20.99 ? 91 HIS C NE2 1 ATOM 3293 N N . GLN B 1 34 ? 25.118 -100.198 38.776 1.00 19.26 ? 92 GLN C N 1 ATOM 3294 C CA . GLN B 1 34 ? 24.951 -99.276 37.646 1.00 26.01 ? 92 GLN C CA 1 ATOM 3295 C C . GLN B 1 34 ? 25.443 -99.795 36.294 1.00 29.06 ? 92 GLN C C 1 ATOM 3296 O O . GLN B 1 34 ? 25.693 -99.006 35.382 1.00 25.38 ? 92 GLN C O 1 ATOM 3297 C CB . GLN B 1 34 ? 25.666 -97.953 37.942 1.00 29.72 ? 92 GLN C CB 1 ATOM 3298 C CG . GLN B 1 34 ? 25.222 -97.270 39.218 1.00 43.42 ? 92 GLN C CG 1 ATOM 3299 C CD . GLN B 1 34 ? 25.740 -95.849 39.314 1.00 45.86 ? 92 GLN C CD 1 ATOM 3300 O OE1 . GLN B 1 34 ? 25.303 -94.967 38.574 1.00 62.19 ? 92 GLN C OE1 1 ATOM 3301 N NE2 . GLN B 1 34 ? 26.683 -95.623 40.219 1.00 40.69 ? 92 GLN C NE2 1 ATOM 3302 N N . SER B 1 35 ? 25.572 -101.108 36.152 1.00 25.54 ? 93 SER C N 1 ATOM 3303 C CA . SER B 1 35 ? 26.033 -101.677 34.891 1.00 26.03 ? 93 SER C CA 1 ATOM 3304 C C . SER B 1 35 ? 25.573 -103.121 34.745 1.00 19.20 ? 93 SER C C 1 ATOM 3305 O O . SER B 1 35 ? 24.911 -103.662 35.627 1.00 20.78 ? 93 SER C O 1 ATOM 3306 C CB . SER B 1 35 ? 27.560 -101.597 34.798 1.00 22.47 ? 93 SER C CB 1 ATOM 3307 O OG . SER B 1 35 ? 28.014 -101.922 33.495 1.00 31.11 ? 93 SER C OG 1 ATOM 3308 N N . GLY B 1 36 ? 25.918 -103.738 33.622 1.00 16.04 ? 94 GLY C N 1 ATOM 3309 C CA . GLY B 1 36 ? 25.615 -105.137 33.408 1.00 19.09 ? 94 GLY C CA 1 ATOM 3310 C C . GLY B 1 36 ? 26.251 -105.997 34.480 1.00 24.26 ? 94 GLY C C 1 ATOM 3311 O O . GLY B 1 36 ? 27.268 -105.624 35.066 1.00 23.76 ? 94 GLY C O 1 ATOM 3312 N N . ILE B 1 37 ? 25.639 -107.147 34.739 1.00 20.05 ? 95 ILE C N 1 ATOM 3313 C CA . ILE B 1 37 ? 26.112 -108.065 35.765 1.00 13.05 ? 95 ILE C CA 1 ATOM 3314 C C . ILE B 1 37 ? 26.565 -109.368 35.122 1.00 17.82 ? 95 ILE C C 1 ATOM 3315 O O . ILE B 1 37 ? 27.684 -109.826 35.353 1.00 21.95 ? 95 ILE C O 1 ATOM 3316 C CB . ILE B 1 37 ? 25.014 -108.333 36.812 1.00 17.02 ? 95 ILE C CB 1 ATOM 3317 C CG1 . ILE B 1 37 ? 24.693 -107.032 37.555 1.00 18.52 ? 95 ILE C CG1 1 ATOM 3318 C CG2 . ILE B 1 37 ? 25.454 -109.411 37.790 1.00 19.17 ? 95 ILE C CG2 1 ATOM 3319 C CD1 . ILE B 1 37 ? 23.557 -107.134 38.549 1.00 22.10 ? 95 ILE C CD1 1 ATOM 3320 N N . TYR B 1 38 ? 25.690 -109.963 34.320 1.00 20.51 ? 96 TYR C N 1 ATOM 3321 C CA . TYR B 1 38 ? 26.030 -111.171 33.580 1.00 15.89 ? 96 TYR C CA 1 ATOM 3322 C C . TYR B 1 38 ? 27.167 -110.852 32.620 1.00 15.67 ? 96 TYR C C 1 ATOM 3323 O O . TYR B 1 38 ? 28.197 -111.525 32.608 1.00 20.08 ? 96 TYR C O 1 ATOM 3324 C CB . TYR B 1 38 ? 24.804 -111.701 32.833 1.00 18.59 ? 96 TYR C CB 1 ATOM 3325 C CG . TYR B 1 38 ? 25.023 -113.010 32.112 1.00 13.19 ? 96 TYR C CG 1 ATOM 3326 C CD1 . TYR B 1 38 ? 25.256 -114.183 32.816 1.00 20.19 ? 96 TYR C CD1 1 ATOM 3327 C CD2 . TYR B 1 38 ? 24.978 -113.075 30.727 1.00 21.65 ? 96 TYR C CD2 1 ATOM 3328 C CE1 . TYR B 1 38 ? 25.451 -115.383 32.160 1.00 22.20 ? 96 TYR C CE1 1 ATOM 3329 C CE2 . TYR B 1 38 ? 25.169 -114.272 30.061 1.00 18.22 ? 96 TYR C CE2 1 ATOM 3330 C CZ . TYR B 1 38 ? 25.406 -115.422 30.784 1.00 23.62 ? 96 TYR C CZ 1 ATOM 3331 O OH . TYR B 1 38 ? 25.599 -116.620 30.135 1.00 24.97 ? 96 TYR C OH 1 ATOM 3332 N N . VAL B 1 39 ? 26.967 -109.807 31.825 1.00 20.42 ? 97 VAL C N 1 ATOM 3333 C CA . VAL B 1 39 ? 28.025 -109.236 31.005 1.00 17.39 ? 97 VAL C CA 1 ATOM 3334 C C . VAL B 1 39 ? 28.113 -107.748 31.331 1.00 24.51 ? 97 VAL C C 1 ATOM 3335 O O . VAL B 1 39 ? 27.139 -107.012 31.171 1.00 16.81 ? 97 VAL C O 1 ATOM 3336 C CB . VAL B 1 39 ? 27.764 -109.456 29.500 1.00 18.87 ? 97 VAL C CB 1 ATOM 3337 C CG1 . VAL B 1 39 ? 28.708 -108.621 28.652 1.00 18.24 ? 97 VAL C CG1 1 ATOM 3338 C CG2 . VAL B 1 39 ? 27.911 -110.929 29.152 1.00 18.79 ? 97 VAL C CG2 1 ATOM 3339 N N . ASP B 1 40 ? 29.278 -107.320 31.807 1.00 18.18 ? 98 ASP C N 1 ATOM 3340 C CA . ASP B 1 40 ? 29.505 -105.924 32.174 1.00 14.99 ? 98 ASP C CA 1 ATOM 3341 C C . ASP B 1 40 ? 30.362 -105.233 31.119 1.00 19.14 ? 98 ASP C C 1 ATOM 3342 O O . ASP B 1 40 ? 31.546 -105.534 30.969 1.00 21.05 ? 98 ASP C O 1 ATOM 3343 C CB . ASP B 1 40 ? 30.166 -105.845 33.556 1.00 14.36 ? 98 ASP C CB 1 ATOM 3344 C CG . ASP B 1 40 ? 30.414 -104.413 34.021 1.00 21.42 ? 98 ASP C CG 1 ATOM 3345 O OD1 . ASP B 1 40 ? 30.040 -103.455 33.310 1.00 19.44 ? 98 ASP C OD1 1 ATOM 3346 O OD2 . ASP B 1 40 ? 30.978 -104.248 35.126 1.00 22.07 ? 98 ASP C OD2 1 ATOM 3347 N N . LEU B 1 41 ? 29.742 -104.313 30.388 1.00 16.22 ? 99 LEU C N 1 ATOM 3348 C CA . LEU B 1 41 ? 30.426 -103.511 29.379 1.00 15.93 ? 99 LEU C CA 1 ATOM 3349 C C . LEU B 1 41 ? 29.783 -102.128 29.335 1.00 15.86 ? 99 LEU C C 1 ATOM 3350 O O . LEU B 1 41 ? 29.410 -101.632 28.272 1.00 26.48 ? 99 LEU C O 1 ATOM 3351 C CB . LEU B 1 41 ? 30.358 -104.182 28.005 1.00 17.28 ? 99 LEU C CB 1 ATOM 3352 C CG . LEU B 1 41 ? 31.110 -105.505 27.859 1.00 16.81 ? 99 LEU C CG 1 ATOM 3353 C CD1 . LEU B 1 41 ? 30.771 -106.160 26.533 1.00 18.31 ? 99 LEU C CD1 1 ATOM 3354 C CD2 . LEU B 1 41 ? 32.610 -105.288 27.978 1.00 18.15 ? 99 LEU C CD2 1 ATOM 3355 N N . GLY B 1 42 ? 29.668 -101.510 30.505 1.00 19.67 ? 100 GLY C N 1 ATOM 3356 C CA . GLY B 1 42 ? 28.858 -100.318 30.664 1.00 22.27 ? 100 GLY C CA 1 ATOM 3357 C C . GLY B 1 42 ? 29.491 -98.998 30.265 1.00 25.99 ? 100 GLY C C 1 ATOM 3358 O O . GLY B 1 42 ? 28.791 -97.987 30.210 1.00 24.06 ? 100 GLY C O 1 ATOM 3359 N N . GLN B 1 43 ? 30.797 -98.988 30.000 1.00 28.62 ? 101 GLN C N 1 ATOM 3360 C CA . GLN B 1 43 ? 31.472 -97.747 29.618 1.00 22.91 ? 101 GLN C CA 1 ATOM 3361 C C . GLN B 1 43 ? 32.164 -97.853 28.266 1.00 23.26 ? 101 GLN C C 1 ATOM 3362 O O . GLN B 1 43 ? 32.408 -98.949 27.763 1.00 25.35 ? 101 GLN C O 1 ATOM 3363 C CB . GLN B 1 43 ? 32.483 -97.348 30.692 1.00 23.22 ? 101 GLN C CB 1 ATOM 3364 C CG . GLN B 1 43 ? 31.863 -96.547 31.823 1.00 31.02 ? 101 GLN C CG 1 ATOM 3365 C CD . GLN B 1 43 ? 32.769 -96.415 33.037 1.00 33.78 ? 101 GLN C CD 1 ATOM 3366 O OE1 . GLN B 1 43 ? 32.322 -96.006 34.109 1.00 35.06 ? 101 GLN C OE1 1 ATOM 3367 N NE2 . GLN B 1 43 ? 34.045 -96.757 32.876 1.00 42.32 ? 101 GLN C NE2 1 ATOM 3368 N N . ASP B 1 44 ? 32.458 -96.694 27.682 1.00 25.78 ? 102 ASP C N 1 ATOM 3369 C CA . ASP B 1 44 ? 33.206 -96.610 26.436 1.00 32.35 ? 102 ASP C CA 1 ATOM 3370 C C . ASP B 1 44 ? 34.424 -95.722 26.638 1.00 39.07 ? 102 ASP C C 1 ATOM 3371 O O . ASP B 1 44 ? 34.317 -94.632 27.202 1.00 33.55 ? 102 ASP C O 1 ATOM 3372 C CB . ASP B 1 44 ? 32.334 -96.060 25.307 1.00 34.23 ? 102 ASP C CB 1 ATOM 3373 C CG . ASP B 1 44 ? 31.117 -96.919 25.042 1.00 45.00 ? 102 ASP C CG 1 ATOM 3374 O OD1 . ASP B 1 44 ? 31.258 -97.954 24.355 1.00 46.14 ? 102 ASP C OD1 1 ATOM 3375 O OD2 . ASP B 1 44 ? 30.020 -96.559 25.519 1.00 52.15 ? 102 ASP C OD2 1 ATOM 3376 N N . LYS B 1 45 ? 35.579 -96.193 26.180 1.00 30.55 ? 103 LYS C N 1 ATOM 3377 C CA . LYS B 1 45 ? 36.820 -95.451 26.343 1.00 32.62 ? 103 LYS C CA 1 ATOM 3378 C C . LYS B 1 45 ? 37.597 -95.365 25.038 1.00 34.90 ? 103 LYS C C 1 ATOM 3379 O O . LYS B 1 45 ? 37.670 -96.327 24.272 1.00 34.43 ? 103 LYS C O 1 ATOM 3380 C CB . LYS B 1 45 ? 37.681 -96.094 27.433 1.00 30.47 ? 103 LYS C CB 1 ATOM 3381 C CG . LYS B 1 45 ? 37.133 -95.908 28.843 1.00 26.39 ? 103 LYS C CG 1 ATOM 3382 C CD . LYS B 1 45 ? 37.228 -94.455 29.297 1.00 28.54 ? 103 LYS C CD 1 ATOM 3383 C CE . LYS B 1 45 ? 36.487 -94.225 30.599 1.00 29.13 ? 103 LYS C CE 1 ATOM 3384 N NZ . LYS B 1 45 ? 36.952 -95.139 31.674 1.00 29.05 ? 103 LYS C NZ 1 ATOM 3385 N N . GLU B 1 46 ? 38.171 -94.191 24.796 1.00 32.56 ? 104 GLU C N 1 ATOM 3386 C CA . GLU B 1 46 ? 38.948 -93.946 23.592 1.00 38.81 ? 104 GLU C CA 1 ATOM 3387 C C . GLU B 1 46 ? 40.413 -94.285 23.827 1.00 32.87 ? 104 GLU C C 1 ATOM 3388 O O . GLU B 1 46 ? 41.030 -93.804 24.778 1.00 34.19 ? 104 GLU C O 1 ATOM 3389 C CB . GLU B 1 46 ? 38.809 -92.490 23.151 1.00 40.83 ? 104 GLU C CB 1 ATOM 3390 C CG . GLU B 1 46 ? 39.197 -92.244 21.702 1.00 64.23 ? 104 GLU C CG 1 ATOM 3391 C CD . GLU B 1 46 ? 38.971 -90.807 21.278 1.00 85.59 ? 104 GLU C CD 1 ATOM 3392 O OE1 . GLU B 1 46 ? 37.890 -90.259 21.581 1.00 83.97 ? 104 GLU C OE1 1 ATOM 3393 O OE2 . GLU B 1 46 ? 39.876 -90.223 20.645 1.00 93.38 ? 104 GLU C OE2 1 ATOM 3394 N N . VAL B 1 47 ? 40.956 -95.129 22.958 1.00 30.77 ? 105 VAL C N 1 ATOM 3395 C CA . VAL B 1 47 ? 42.368 -95.473 22.983 1.00 32.61 ? 105 VAL C CA 1 ATOM 3396 C C . VAL B 1 47 ? 42.895 -95.394 21.558 1.00 38.29 ? 105 VAL C C 1 ATOM 3397 O O . VAL B 1 47 ? 42.317 -95.983 20.642 1.00 38.02 ? 105 VAL C O 1 ATOM 3398 C CB . VAL B 1 47 ? 42.610 -96.881 23.568 1.00 33.41 ? 105 VAL C CB 1 ATOM 3399 C CG1 . VAL B 1 47 ? 44.096 -97.217 23.579 1.00 37.07 ? 105 VAL C CG1 1 ATOM 3400 C CG2 . VAL B 1 47 ? 42.043 -96.975 24.974 1.00 30.48 ? 105 VAL C CG2 1 ATOM 3401 N N . ASP B 1 48 ? 43.978 -94.640 21.384 1.00 31.54 ? 106 ASP C N 1 ATOM 3402 C CA . ASP B 1 48 ? 44.623 -94.459 20.085 1.00 31.08 ? 106 ASP C CA 1 ATOM 3403 C C . ASP B 1 48 ? 43.614 -94.166 18.974 1.00 30.70 ? 106 ASP C C 1 ATOM 3404 O O . ASP B 1 48 ? 43.693 -94.725 17.881 1.00 34.58 ? 106 ASP C O 1 ATOM 3405 C CB . ASP B 1 48 ? 45.455 -95.695 19.733 1.00 35.96 ? 106 ASP C CB 1 ATOM 3406 C CG . ASP B 1 48 ? 46.707 -95.812 20.581 1.00 52.33 ? 106 ASP C CG 1 ATOM 3407 O OD1 . ASP B 1 48 ? 47.435 -94.805 20.706 1.00 47.47 ? 106 ASP C OD1 1 ATOM 3408 O OD2 . ASP B 1 48 ? 46.964 -96.907 21.126 1.00 46.82 ? 106 ASP C OD2 1 ATOM 3409 N N . GLY B 1 49 ? 42.659 -93.293 19.275 1.00 33.90 ? 107 GLY C N 1 ATOM 3410 C CA . GLY B 1 49 ? 41.697 -92.843 18.289 1.00 45.12 ? 107 GLY C CA 1 ATOM 3411 C C . GLY B 1 49 ? 40.454 -93.705 18.156 1.00 51.98 ? 107 GLY C C 1 ATOM 3412 O O . GLY B 1 49 ? 39.486 -93.284 17.521 1.00 49.02 ? 107 GLY C O 1 ATOM 3413 N N . THR B 1 50 ? 40.467 -94.898 18.750 1.00 46.78 ? 108 THR C N 1 ATOM 3414 C CA . THR B 1 50 ? 39.351 -95.831 18.595 1.00 36.04 ? 108 THR C CA 1 ATOM 3415 C C . THR B 1 50 ? 38.600 -96.044 19.906 1.00 44.80 ? 108 THR C C 1 ATOM 3416 O O . THR B 1 50 ? 39.194 -96.051 20.984 1.00 34.24 ? 108 THR C O 1 ATOM 3417 C CB . THR B 1 50 ? 39.833 -97.195 18.060 1.00 44.07 ? 108 THR C CB 1 ATOM 3418 O OG1 . THR B 1 50 ? 40.566 -96.998 16.846 1.00 47.43 ? 108 THR C OG1 1 ATOM 3419 C CG2 . THR B 1 50 ? 38.646 -98.120 17.786 1.00 40.92 ? 108 THR C CG2 1 ATOM 3420 N N . LEU B 1 51 ? 37.292 -96.234 19.792 1.00 39.05 ? 109 LEU C N 1 ATOM 3421 C CA . LEU B 1 51 ? 36.433 -96.472 20.938 1.00 42.78 ? 109 LEU C CA 1 ATOM 3422 C C . LEU B 1 51 ? 36.346 -97.936 21.308 1.00 36.08 ? 109 LEU C C 1 ATOM 3423 O O . LEU B 1 51 ? 36.165 -98.786 20.466 1.00 30.68 ? 109 LEU C O 1 ATOM 3424 C CB . LEU B 1 51 ? 35.029 -95.940 20.693 1.00 45.20 ? 109 LEU C CB 1 ATOM 3425 C CG . LEU B 1 51 ? 34.745 -94.499 21.093 1.00 48.39 ? 109 LEU C CG 1 ATOM 3426 C CD1 . LEU B 1 51 ? 33.264 -94.214 20.991 1.00 50.24 ? 109 LEU C CD1 1 ATOM 3427 C CD2 . LEU B 1 51 ? 35.228 -94.246 22.498 1.00 47.82 ? 109 LEU C CD2 1 ATOM 3428 N N . TYR B 1 52 ? 36.476 -98.217 22.588 1.00 29.65 ? 110 TYR C N 1 ATOM 3429 C CA . TYR B 1 52 ? 36.376 -99.593 23.071 1.00 26.31 ? 110 TYR C CA 1 ATOM 3430 C C . TYR B 1 52 ? 35.432 -99.695 24.264 1.00 26.29 ? 110 TYR C C 1 ATOM 3431 O O . TYR B 1 52 ? 35.326 -98.764 25.062 1.00 29.35 ? 110 TYR C O 1 ATOM 3432 C CB . TYR B 1 52 ? 37.757 -100.124 23.454 1.00 24.34 ? 110 TYR C CB 1 ATOM 3433 C CG . TYR B 1 52 ? 38.736 -100.144 22.306 1.00 29.60 ? 110 TYR C CG 1 ATOM 3434 C CD1 . TYR B 1 52 ? 39.514 -99.034 22.018 1.00 29.14 ? 110 TYR C CD1 1 ATOM 3435 C CD2 . TYR B 1 52 ? 38.882 -101.272 21.511 1.00 26.22 ? 110 TYR C CD2 1 ATOM 3436 C CE1 . TYR B 1 52 ? 40.410 -99.043 20.972 1.00 31.94 ? 110 TYR C CE1 1 ATOM 3437 C CE2 . TYR B 1 52 ? 39.778 -101.292 20.461 1.00 34.26 ? 110 TYR C CE2 1 ATOM 3438 C CZ . TYR B 1 52 ? 40.541 -100.173 20.195 1.00 29.57 ? 110 TYR C CZ 1 ATOM 3439 O OH . TYR B 1 52 ? 41.437 -100.179 19.152 1.00 36.04 ? 110 TYR C OH 1 ATOM 3440 N N . ARG B 1 53 ? 34.753 -100.832 24.385 1.00 21.27 ? 111 ARG C N 1 ATOM 3441 C CA . ARG B 1 53 ? 33.838 -101.052 25.501 1.00 23.69 ? 111 ARG C CA 1 ATOM 3442 C C . ARG B 1 53 ? 34.621 -101.448 26.747 1.00 17.81 ? 111 ARG C C 1 ATOM 3443 O O . ARG B 1 53 ? 35.650 -102.119 26.657 1.00 25.56 ? 111 ARG C O 1 ATOM 3444 C CB . ARG B 1 53 ? 32.806 -102.129 25.163 1.00 21.00 ? 111 ARG C CB 1 ATOM 3445 C CG . ARG B 1 53 ? 32.026 -101.863 23.883 1.00 23.48 ? 111 ARG C CG 1 ATOM 3446 C CD . ARG B 1 53 ? 30.770 -102.724 23.812 1.00 21.34 ? 111 ARG C CD 1 ATOM 3447 N NE . ARG B 1 53 ? 29.755 -102.290 24.773 1.00 21.29 ? 111 ARG C NE 1 ATOM 3448 C CZ . ARG B 1 53 ? 28.618 -102.938 25.012 1.00 18.37 ? 111 ARG C CZ 1 ATOM 3449 N NH1 . ARG B 1 53 ? 28.335 -104.063 24.367 1.00 24.76 ? 111 ARG C NH1 1 ATOM 3450 N NH2 . ARG B 1 53 ? 27.760 -102.460 25.902 1.00 19.89 ? 111 ARG C NH2 1 ATOM 3451 N N . GLU B 1 54 ? 34.120 -101.035 27.906 1.00 20.50 ? 112 GLU C N 1 ATOM 3452 C CA . GLU B 1 54 ? 34.835 -101.210 29.163 1.00 20.17 ? 112 GLU C CA 1 ATOM 3453 C C . GLU B 1 54 ? 33.874 -101.588 30.291 1.00 12.41 ? 112 GLU C C 1 ATOM 3454 O O . GLU B 1 54 ? 32.850 -100.922 30.479 1.00 26.49 ? 112 GLU C O 1 ATOM 3455 C CB . GLU B 1 54 ? 35.585 -99.925 29.520 1.00 23.41 ? 112 GLU C CB 1 ATOM 3456 C CG . GLU B 1 54 ? 36.483 -100.037 30.749 1.00 25.03 ? 112 GLU C CG 1 ATOM 3457 C CD . GLU B 1 54 ? 36.909 -98.682 31.292 1.00 29.10 ? 112 GLU C CD 1 ATOM 3458 O OE1 . GLU B 1 54 ? 36.089 -97.739 31.266 1.00 27.57 ? 112 GLU C OE1 1 ATOM 3459 O OE2 . GLU B 1 54 ? 38.064 -98.557 31.748 1.00 30.50 ? 112 GLU C OE2 1 ATOM 3460 N N . PRO B 1 55 ? 34.191 -102.664 31.037 1.00 17.85 ? 113 PRO C N 1 ATOM 3461 C CA . PRO B 1 55 ? 33.421 -102.983 32.246 1.00 20.72 ? 113 PRO C CA 1 ATOM 3462 C C . PRO B 1 55 ? 33.430 -101.813 33.227 1.00 22.19 ? 113 PRO C C 1 ATOM 3463 O O . PRO B 1 55 ? 34.472 -101.179 33.389 1.00 28.14 ? 113 PRO C O 1 ATOM 3464 C CB . PRO B 1 55 ? 34.151 -104.200 32.823 1.00 18.07 ? 113 PRO C CB 1 ATOM 3465 C CG . PRO B 1 55 ? 34.834 -104.821 31.661 1.00 20.01 ? 113 PRO C CG 1 ATOM 3466 C CD . PRO B 1 55 ? 35.214 -103.688 30.755 1.00 18.04 ? 113 PRO C CD 1 ATOM 3467 N N . ALA B 1 56 ? 32.294 -101.539 33.864 1.00 20.41 ? 114 ALA C N 1 ATOM 3468 C CA . ALA B 1 56 ? 32.121 -100.307 34.629 1.00 22.81 ? 114 ALA C CA 1 ATOM 3469 C C . ALA B 1 56 ? 31.417 -100.519 35.968 1.00 21.96 ? 114 ALA C C 1 ATOM 3470 O O . ALA B 1 56 ? 31.268 -99.578 36.749 1.00 23.59 ? 114 ALA C O 1 ATOM 3471 C CB . ALA B 1 56 ? 31.345 -99.302 33.795 1.00 24.43 ? 114 ALA C CB 1 ATOM 3472 N N . GLY B 1 57 ? 30.990 -101.749 36.233 1.00 15.91 ? 115 GLY C N 1 ATOM 3473 C CA . GLY B 1 57 ? 30.221 -102.050 37.429 1.00 18.99 ? 115 GLY C CA 1 ATOM 3474 C C . GLY B 1 57 ? 30.963 -101.742 38.718 1.00 18.24 ? 115 GLY C C 1 ATOM 3475 O O . GLY B 1 57 ? 32.163 -101.990 38.831 1.00 23.97 ? 115 GLY C O 1 ATOM 3476 N N . LEU B 1 58 ? 30.233 -101.214 39.696 1.00 21.21 ? 116 LEU C N 1 ATOM 3477 C CA . LEU B 1 58 ? 30.814 -100.768 40.960 1.00 19.30 ? 116 LEU C CA 1 ATOM 3478 C C . LEU B 1 58 ? 30.771 -101.822 42.064 1.00 26.81 ? 116 LEU C C 1 ATOM 3479 O O . LEU B 1 58 ? 31.348 -101.622 43.133 1.00 27.78 ? 116 LEU C O 1 ATOM 3480 C CB . LEU B 1 58 ? 30.087 -99.512 41.438 1.00 22.91 ? 116 LEU C CB 1 ATOM 3481 C CG . LEU B 1 58 ? 30.632 -98.147 41.015 1.00 33.91 ? 116 LEU C CG 1 ATOM 3482 C CD1 . LEU B 1 58 ? 31.042 -98.135 39.562 1.00 32.85 ? 116 LEU C CD1 1 ATOM 3483 C CD2 . LEU B 1 58 ? 29.573 -97.089 41.268 1.00 33.00 ? 116 LEU C CD2 1 ATOM 3484 N N . CYS B 1 59 ? 30.084 -102.934 41.818 1.00 20.73 ? 117 CYS C N 1 ATOM 3485 C CA . CYS B 1 59 ? 29.993 -104.003 42.810 1.00 20.83 ? 117 CYS C CA 1 ATOM 3486 C C . CYS B 1 59 ? 30.779 -105.236 42.382 1.00 21.53 ? 117 CYS C C 1 ATOM 3487 O O . CYS B 1 59 ? 30.823 -105.569 41.197 1.00 25.12 ? 117 CYS C O 1 ATOM 3488 C CB . CYS B 1 59 ? 28.532 -104.382 43.064 1.00 25.31 ? 117 CYS C CB 1 ATOM 3489 S SG . CYS B 1 59 ? 27.626 -103.169 44.057 1.00 44.47 ? 117 CYS C SG 1 ATOM 3490 N N . PRO B 1 60 ? 31.416 -105.917 43.349 1.00 18.22 ? 118 PRO C N 1 ATOM 3491 C CA . PRO B 1 60 ? 32.058 -107.188 43.012 1.00 22.67 ? 118 PRO C CA 1 ATOM 3492 C C . PRO B 1 60 ? 31.007 -108.265 42.764 1.00 19.84 ? 118 PRO C C 1 ATOM 3493 O O . PRO B 1 60 ? 29.947 -108.225 43.388 1.00 17.59 ? 118 PRO C O 1 ATOM 3494 C CB . PRO B 1 60 ? 32.903 -107.499 44.248 1.00 20.56 ? 118 PRO C CB 1 ATOM 3495 C CG . PRO B 1 60 ? 32.206 -106.813 45.364 1.00 21.66 ? 118 PRO C CG 1 ATOM 3496 C CD . PRO B 1 60 ? 31.557 -105.588 44.779 1.00 18.43 ? 118 PRO C CD 1 ATOM 3497 N N . ILE B 1 61 ? 31.297 -109.196 41.861 1.00 17.72 ? 119 ILE C N 1 ATOM 3498 C CA . ILE B 1 61 ? 30.362 -110.265 41.523 1.00 13.17 ? 119 ILE C CA 1 ATOM 3499 C C . ILE B 1 61 ? 30.906 -111.587 42.046 1.00 11.60 ? 119 ILE C C 1 ATOM 3500 O O . ILE B 1 61 ? 31.833 -112.162 41.478 1.00 18.57 ? 119 ILE C O 1 ATOM 3501 C CB . ILE B 1 61 ? 30.123 -110.352 40.005 1.00 18.48 ? 119 ILE C CB 1 ATOM 3502 C CG1 . ILE B 1 61 ? 29.800 -108.966 39.434 1.00 20.22 ? 119 ILE C CG1 1 ATOM 3503 C CG2 . ILE B 1 61 ? 29.001 -111.336 39.691 1.00 19.22 ? 119 ILE C CG2 1 ATOM 3504 C CD1 . ILE B 1 61 ? 28.597 -108.301 40.061 1.00 21.48 ? 119 ILE C CD1 1 ATOM 3505 N N . TRP B 1 62 ? 30.320 -112.056 43.141 1.00 18.49 ? 120 TRP C N 1 ATOM 3506 C CA . TRP B 1 62 ? 30.826 -113.222 43.853 1.00 15.72 ? 120 TRP C CA 1 ATOM 3507 C C . TRP B 1 62 ? 30.536 -114.528 43.118 1.00 17.62 ? 120 TRP C C 1 ATOM 3508 O O . TRP B 1 62 ? 29.385 -114.833 42.801 1.00 15.56 ? 120 TRP C O 1 ATOM 3509 C CB . TRP B 1 62 ? 30.219 -113.276 45.257 1.00 15.30 ? 120 TRP C CB 1 ATOM 3510 C CG . TRP B 1 62 ? 30.592 -112.109 46.130 1.00 18.02 ? 120 TRP C CG 1 ATOM 3511 C CD1 . TRP B 1 62 ? 30.221 -110.804 45.963 1.00 19.13 ? 120 TRP C CD1 1 ATOM 3512 C CD2 . TRP B 1 62 ? 31.397 -112.147 47.315 1.00 15.12 ? 120 TRP C CD2 1 ATOM 3513 N NE1 . TRP B 1 62 ? 30.749 -110.029 46.968 1.00 19.94 ? 120 TRP C NE1 1 ATOM 3514 C CE2 . TRP B 1 62 ? 31.475 -110.830 47.810 1.00 22.76 ? 120 TRP C CE2 1 ATOM 3515 C CE3 . TRP B 1 62 ? 32.060 -113.168 48.004 1.00 18.32 ? 120 TRP C CE3 1 ATOM 3516 C CZ2 . TRP B 1 62 ? 32.192 -110.506 48.961 1.00 19.30 ? 120 TRP C CZ2 1 ATOM 3517 C CZ3 . TRP B 1 62 ? 32.769 -112.844 49.146 1.00 22.45 ? 120 TRP C CZ3 1 ATOM 3518 C CH2 . TRP B 1 62 ? 32.829 -111.525 49.613 1.00 18.72 ? 120 TRP C CH2 1 ATOM 3519 N N . GLY B 1 63 ? 31.592 -115.294 42.858 1.00 11.79 ? 121 GLY C N 1 ATOM 3520 C CA . GLY B 1 63 ? 31.467 -116.601 42.241 1.00 18.89 ? 121 GLY C CA 1 ATOM 3521 C C . GLY B 1 63 ? 31.503 -116.578 40.723 1.00 19.80 ? 121 GLY C C 1 ATOM 3522 O O . GLY B 1 63 ? 31.627 -117.627 40.090 1.00 17.27 ? 121 GLY C O 1 ATOM 3523 N N . LYS B 1 64 ? 31.396 -115.394 40.129 1.00 16.85 ? 122 LYS C N 1 ATOM 3524 C CA . LYS B 1 64 ? 31.395 -115.289 38.672 1.00 13.96 ? 122 LYS C CA 1 ATOM 3525 C C . LYS B 1 64 ? 32.737 -115.693 38.086 1.00 20.15 ? 122 LYS C C 1 ATOM 3526 O O . LYS B 1 64 ? 33.783 -115.183 38.492 1.00 24.16 ? 122 LYS C O 1 ATOM 3527 C CB . LYS B 1 64 ? 31.051 -113.866 38.222 1.00 16.13 ? 122 LYS C CB 1 ATOM 3528 C CG . LYS B 1 64 ? 31.265 -113.626 36.730 1.00 15.29 ? 122 LYS C CG 1 ATOM 3529 C CD . LYS B 1 64 ? 30.818 -112.245 36.304 1.00 14.02 ? 122 LYS C CD 1 ATOM 3530 C CE . LYS B 1 64 ? 31.215 -111.977 34.862 1.00 14.00 ? 122 LYS C CE 1 ATOM 3531 N NZ . LYS B 1 64 ? 30.707 -110.674 34.356 1.00 16.65 ? 122 LYS C NZ 1 ATOM 3532 N N . HIS B 1 65 ? 32.702 -116.617 37.131 1.00 14.53 ? 123 HIS C N 1 ATOM 3533 C CA . HIS B 1 65 ? 33.890 -116.940 36.354 1.00 12.46 ? 123 HIS C CA 1 ATOM 3534 C C . HIS B 1 65 ? 33.505 -117.117 34.890 1.00 20.08 ? 123 HIS C C 1 ATOM 3535 O O . HIS B 1 65 ? 32.324 -117.207 34.564 1.00 16.76 ? 123 HIS C O 1 ATOM 3536 C CB . HIS B 1 65 ? 34.576 -118.194 36.900 1.00 15.44 ? 123 HIS C CB 1 ATOM 3537 C CG . HIS B 1 65 ? 33.689 -119.396 36.959 1.00 21.87 ? 123 HIS C CG 1 ATOM 3538 N ND1 . HIS B 1 65 ? 32.665 -119.523 37.873 1.00 24.08 ? 123 HIS C ND1 1 ATOM 3539 C CD2 . HIS B 1 65 ? 33.682 -120.534 36.226 1.00 25.44 ? 123 HIS C CD2 1 ATOM 3540 C CE1 . HIS B 1 65 ? 32.062 -120.685 37.697 1.00 22.19 ? 123 HIS C CE1 1 ATOM 3541 N NE2 . HIS B 1 65 ? 32.659 -121.317 36.702 1.00 25.22 ? 123 HIS C NE2 1 ATOM 3542 N N . ILE B 1 66 ? 34.501 -117.134 34.010 1.00 19.80 ? 124 ILE C N 1 ATOM 3543 C CA . ILE B 1 66 ? 34.257 -117.308 32.583 1.00 15.61 ? 124 ILE C CA 1 ATOM 3544 C C . ILE B 1 66 ? 34.604 -118.732 32.187 1.00 18.40 ? 124 ILE C C 1 ATOM 3545 O O . ILE B 1 66 ? 35.762 -119.148 32.278 1.00 21.76 ? 124 ILE C O 1 ATOM 3546 C CB . ILE B 1 66 ? 35.077 -116.326 31.725 1.00 21.16 ? 124 ILE C CB 1 ATOM 3547 C CG1 . ILE B 1 66 ? 34.905 -114.889 32.227 1.00 16.56 ? 124 ILE C CG1 1 ATOM 3548 C CG2 . ILE B 1 66 ? 34.667 -116.431 30.259 1.00 21.18 ? 124 ILE C CG2 1 ATOM 3549 C CD1 . ILE B 1 66 ? 33.479 -114.385 32.209 1.00 14.57 ? 124 ILE C CD1 1 ATOM 3550 N N . GLU B 1 67 ? 33.587 -119.478 31.769 1.00 13.48 ? 125 GLU C N 1 ATOM 3551 C CA . GLU B 1 67 ? 33.765 -120.845 31.297 1.00 21.47 ? 125 GLU C CA 1 ATOM 3552 C C . GLU B 1 67 ? 34.156 -120.863 29.823 1.00 18.57 ? 125 GLU C C 1 ATOM 3553 O O . GLU B 1 67 ? 33.527 -120.197 28.992 1.00 18.49 ? 125 GLU C O 1 ATOM 3554 C CB . GLU B 1 67 ? 32.485 -121.653 31.512 1.00 21.90 ? 125 GLU C CB 1 ATOM 3555 C CG . GLU B 1 67 ? 32.595 -123.117 31.112 1.00 27.17 ? 125 GLU C CG 1 ATOM 3556 C CD . GLU B 1 67 ? 31.312 -123.888 31.369 1.00 77.81 ? 125 GLU C CD 1 ATOM 3557 O OE1 . GLU B 1 67 ? 31.257 -124.644 32.363 1.00 65.45 ? 125 GLU C OE1 1 ATOM 3558 O OE2 . GLU B 1 67 ? 30.358 -123.740 30.575 1.00 47.17 ? 125 GLU C OE2 1 ATOM 3559 N N . LEU B 1 68 ? 35.194 -121.639 29.522 1.00 19.01 ? 126 LEU C N 1 ATOM 3560 C CA . LEU B 1 68 ? 35.756 -121.753 28.179 1.00 20.57 ? 126 LEU C CA 1 ATOM 3561 C C . LEU B 1 68 ? 35.371 -123.074 27.519 1.00 24.02 ? 126 LEU C C 1 ATOM 3562 O O . LEU B 1 68 ? 35.022 -124.038 28.200 1.00 20.47 ? 126 LEU C O 1 ATOM 3563 C CB . LEU B 1 68 ? 37.282 -121.644 28.236 1.00 24.14 ? 126 LEU C CB 1 ATOM 3564 C CG . LEU B 1 68 ? 37.913 -120.256 28.346 1.00 25.97 ? 126 LEU C CG 1 ATOM 3565 C CD1 . LEU B 1 68 ? 37.154 -119.350 29.289 1.00 22.34 ? 126 LEU C CD1 1 ATOM 3566 C CD2 . LEU B 1 68 ? 39.364 -120.391 28.791 1.00 20.63 ? 126 LEU C CD2 1 ATOM 3567 N N . GLN B 1 69 ? 35.455 -123.116 26.191 1.00 22.45 ? 127 GLN C N 1 ATOM 3568 C CA . GLN B 1 69 ? 35.179 -124.336 25.439 1.00 22.16 ? 127 GLN C CA 1 ATOM 3569 C C . GLN B 1 69 ? 36.287 -124.623 24.430 1.00 20.29 ? 127 GLN C C 1 ATOM 3570 O O . GLN B 1 69 ? 36.042 -124.754 23.231 1.00 19.16 ? 127 GLN C O 1 ATOM 3571 C CB . GLN B 1 69 ? 33.825 -124.231 24.738 1.00 25.33 ? 127 GLN C CB 1 ATOM 3572 C CG . GLN B 1 69 ? 32.663 -124.102 25.711 1.00 28.04 ? 127 GLN C CG 1 ATOM 3573 C CD . GLN B 1 69 ? 31.317 -124.093 25.019 1.00 39.24 ? 127 GLN C CD 1 ATOM 3574 O OE1 . GLN B 1 69 ? 30.819 -123.041 24.617 1.00 48.96 ? 127 GLN C OE1 1 ATOM 3575 N NE2 . GLN B 1 69 ? 30.718 -125.269 24.878 1.00 47.15 ? 127 GLN C NE2 1 ATOM 3576 N N . GLN B 1 70 ? 37.511 -124.718 24.938 1.00 20.51 ? 128 GLN C N 1 ATOM 3577 C CA . GLN B 1 70 ? 38.650 -125.140 24.138 1.00 24.82 ? 128 GLN C CA 1 ATOM 3578 C C . GLN B 1 70 ? 38.616 -126.654 23.981 1.00 23.65 ? 128 GLN C C 1 ATOM 3579 O O . GLN B 1 70 ? 37.880 -127.331 24.694 1.00 24.13 ? 128 GLN C O 1 ATOM 3580 C CB . GLN B 1 70 ? 39.964 -124.710 24.797 1.00 14.91 ? 128 GLN C CB 1 ATOM 3581 C CG . GLN B 1 70 ? 40.117 -123.208 24.986 1.00 20.05 ? 128 GLN C CG 1 ATOM 3582 C CD . GLN B 1 70 ? 41.264 -122.846 25.916 1.00 18.06 ? 128 GLN C CD 1 ATOM 3583 O OE1 . GLN B 1 70 ? 41.438 -123.453 26.973 1.00 20.10 ? 128 GLN C OE1 1 ATOM 3584 N NE2 . GLN B 1 70 ? 42.056 -121.852 25.522 1.00 19.95 ? 128 GLN C NE2 1 ATOM 3585 N N . PRO B 1 71 ? 39.413 -127.193 23.045 1.00 21.00 ? 129 PRO C N 1 ATOM 3586 C CA . PRO B 1 71 ? 39.608 -128.646 22.980 1.00 28.20 ? 129 PRO C CA 1 ATOM 3587 C C . PRO B 1 71 ? 40.118 -129.206 24.306 1.00 28.91 ? 129 PRO C C 1 ATOM 3588 O O . PRO B 1 71 ? 40.681 -128.454 25.100 1.00 28.49 ? 129 PRO C O 1 ATOM 3589 C CB . PRO B 1 71 ? 40.655 -128.812 21.877 1.00 26.98 ? 129 PRO C CB 1 ATOM 3590 C CG . PRO B 1 71 ? 40.508 -127.599 21.027 1.00 27.44 ? 129 PRO C CG 1 ATOM 3591 C CD . PRO B 1 71 ? 40.104 -126.492 21.949 1.00 17.99 ? 129 PRO C CD 1 ATOM 3592 N N . ASP B 1 72 ? 39.929 -130.501 24.539 1.00 33.08 ? 130 ASP C N 1 ATOM 3593 C CA . ASP B 1 72 ? 40.349 -131.123 25.793 1.00 33.90 ? 130 ASP C CA 1 ATOM 3594 C C . ASP B 1 72 ? 41.824 -131.515 25.782 1.00 33.58 ? 130 ASP C C 1 ATOM 3595 O O . ASP B 1 72 ? 42.444 -131.658 26.836 1.00 53.57 ? 130 ASP C O 1 ATOM 3596 C CB . ASP B 1 72 ? 39.493 -132.357 26.085 1.00 53.71 ? 130 ASP C CB 1 ATOM 3597 C CG . ASP B 1 72 ? 38.067 -132.005 26.468 1.00 72.05 ? 130 ASP C CG 1 ATOM 3598 O OD1 . ASP B 1 72 ? 37.826 -130.856 26.898 1.00 71.83 ? 130 ASP C OD1 1 ATOM 3599 O OD2 . ASP B 1 72 ? 37.186 -132.881 26.345 1.00 87.13 ? 130 ASP C OD2 1 ATOM 3600 N N . ARG B 1 73 ? 42.382 -131.691 24.590 1.00 29.41 ? 131 ARG C N 1 ATOM 3601 C CA . ARG B 1 73 ? 43.771 -132.111 24.448 1.00 31.81 ? 131 ARG C CA 1 ATOM 3602 C C . ARG B 1 73 ? 44.746 -131.055 24.967 1.00 34.74 ? 131 ARG C C 1 ATOM 3603 O O . ARG B 1 73 ? 44.405 -129.876 25.044 1.00 30.95 ? 131 ARG C O 1 ATOM 3604 C CB . ARG B 1 73 ? 44.080 -132.412 22.979 1.00 27.33 ? 131 ARG C CB 1 ATOM 3605 C CG . ARG B 1 73 ? 44.031 -131.185 22.070 1.00 41.41 ? 131 ARG C CG 1 ATOM 3606 C CD . ARG B 1 73 ? 44.193 -131.560 20.607 1.00 41.25 ? 131 ARG C CD 1 ATOM 3607 N NE . ARG B 1 73 ? 43.036 -132.292 20.102 1.00 70.17 ? 131 ARG C NE 1 ATOM 3608 C CZ . ARG B 1 73 ? 42.988 -132.900 18.921 1.00 110.45 ? 131 ARG C CZ 1 ATOM 3609 N NH1 . ARG B 1 73 ? 41.887 -133.539 18.552 1.00 95.70 ? 131 ARG C NH1 1 ATOM 3610 N NH2 . ARG B 1 73 ? 44.038 -132.874 18.108 1.00 60.56 ? 131 ARG C NH2 1 ATOM 3611 N N . PRO B 1 74 ? 45.967 -131.477 25.335 1.00 38.23 ? 132 PRO C N 1 ATOM 3612 C CA . PRO B 1 74 ? 47.022 -130.485 25.559 1.00 40.34 ? 132 PRO C CA 1 ATOM 3613 C C . PRO B 1 74 ? 47.277 -129.684 24.284 1.00 36.48 ? 132 PRO C C 1 ATOM 3614 O O . PRO B 1 74 ? 47.075 -130.218 23.195 1.00 36.86 ? 132 PRO C O 1 ATOM 3615 C CB . PRO B 1 74 ? 48.237 -131.340 25.936 1.00 37.95 ? 132 PRO C CB 1 ATOM 3616 C CG . PRO B 1 74 ? 47.654 -132.591 26.499 1.00 41.88 ? 132 PRO C CG 1 ATOM 3617 C CD . PRO B 1 74 ? 46.393 -132.834 25.720 1.00 38.36 ? 132 PRO C CD 1 ATOM 3618 N N . PRO B 1 75 ? 47.721 -128.424 24.405 1.00 26.99 ? 133 PRO C N 1 ATOM 3619 C CA . PRO B 1 75 ? 48.069 -127.693 25.627 1.00 26.74 ? 133 PRO C CA 1 ATOM 3620 C C . PRO B 1 75 ? 46.897 -126.951 26.277 1.00 31.92 ? 133 PRO C C 1 ATOM 3621 O O . PRO B 1 75 ? 47.121 -126.167 27.199 1.00 32.98 ? 133 PRO C O 1 ATOM 3622 C CB . PRO B 1 75 ? 49.115 -126.697 25.129 1.00 31.00 ? 133 PRO C CB 1 ATOM 3623 C CG . PRO B 1 75 ? 48.661 -126.376 23.742 1.00 32.61 ? 133 PRO C CG 1 ATOM 3624 C CD . PRO B 1 75 ? 48.019 -127.632 23.198 1.00 32.02 ? 133 PRO C CD 1 ATOM 3625 N N . TYR B 1 76 ? 45.676 -127.192 25.812 1.00 25.60 ? 134 TYR C N 1 ATOM 3626 C CA . TYR B 1 76 ? 44.513 -126.470 26.325 1.00 26.97 ? 134 TYR C CA 1 ATOM 3627 C C . TYR B 1 76 ? 44.138 -126.925 27.732 1.00 24.03 ? 134 TYR C C 1 ATOM 3628 O O . TYR B 1 76 ? 44.150 -128.119 28.032 1.00 27.71 ? 134 TYR C O 1 ATOM 3629 C CB . TYR B 1 76 ? 43.320 -126.650 25.389 1.00 21.20 ? 134 TYR C CB 1 ATOM 3630 C CG . TYR B 1 76 ? 43.575 -126.183 23.976 1.00 14.22 ? 134 TYR C CG 1 ATOM 3631 C CD1 . TYR B 1 76 ? 43.437 -124.847 23.633 1.00 14.90 ? 134 TYR C CD1 1 ATOM 3632 C CD2 . TYR B 1 76 ? 43.947 -127.080 22.984 1.00 23.10 ? 134 TYR C CD2 1 ATOM 3633 C CE1 . TYR B 1 76 ? 43.664 -124.414 22.341 1.00 17.64 ? 134 TYR C CE1 1 ATOM 3634 C CE2 . TYR B 1 76 ? 44.177 -126.657 21.687 1.00 18.62 ? 134 TYR C CE2 1 ATOM 3635 C CZ . TYR B 1 76 ? 44.033 -125.322 21.373 1.00 15.72 ? 134 TYR C CZ 1 ATOM 3636 O OH . TYR B 1 76 ? 44.260 -124.892 20.088 1.00 21.02 ? 134 TYR C OH 1 ATOM 3637 N N . ARG B 1 77 ? 43.789 -125.961 28.582 1.00 25.17 ? 135 ARG C N 1 ATOM 3638 C CA . ARG B 1 77 ? 43.500 -126.220 29.990 1.00 28.36 ? 135 ARG C CA 1 ATOM 3639 C C . ARG B 1 77 ? 42.071 -125.829 30.368 1.00 29.83 ? 135 ARG C C 1 ATOM 3640 O O . ARG B 1 77 ? 41.590 -126.185 31.444 1.00 28.56 ? 135 ARG C O 1 ATOM 3641 C CB . ARG B 1 77 ? 44.491 -125.459 30.877 1.00 38.82 ? 135 ARG C CB 1 ATOM 3642 C CG . ARG B 1 77 ? 45.958 -125.686 30.521 1.00 41.85 ? 135 ARG C CG 1 ATOM 3643 C CD . ARG B 1 77 ? 46.470 -127.014 31.044 1.00 41.19 ? 135 ARG C CD 1 ATOM 3644 N NE . ARG B 1 77 ? 46.814 -126.931 32.464 1.00 64.25 ? 135 ARG C NE 1 ATOM 3645 C CZ . ARG B 1 77 ? 46.345 -127.730 33.422 1.00 74.84 ? 135 ARG C CZ 1 ATOM 3646 N NH1 . ARG B 1 77 ? 45.495 -128.713 33.147 1.00 68.89 ? 135 ARG C NH1 1 ATOM 3647 N NH2 . ARG B 1 77 ? 46.737 -127.544 34.674 1.00 75.08 ? 135 ARG C NH2 1 ATOM 3648 N N . ASN B 1 78 ? 41.400 -125.099 29.479 1.00 25.31 ? 136 ASN C N 1 ATOM 3649 C CA . ASN B 1 78 ? 40.055 -124.586 29.740 1.00 28.31 ? 136 ASN C CA 1 ATOM 3650 C C . ASN B 1 78 ? 39.957 -123.901 31.100 1.00 27.39 ? 136 ASN C C 1 ATOM 3651 O O . ASN B 1 78 ? 39.211 -124.328 31.981 1.00 25.52 ? 136 ASN C O 1 ATOM 3652 C CB . ASN B 1 78 ? 39.025 -125.712 29.632 1.00 23.92 ? 136 ASN C CB 1 ATOM 3653 C CG . ASN B 1 78 ? 38.660 -126.022 28.196 1.00 24.84 ? 136 ASN C CG 1 ATOM 3654 O OD1 . ASN B 1 78 ? 37.953 -125.249 27.548 1.00 26.92 ? 136 ASN C OD1 1 ATOM 3655 N ND2 . ASN B 1 78 ? 39.143 -127.149 27.686 1.00 30.82 ? 136 ASN C ND2 1 ATOM 3656 N N . ASN B 1 79 ? 40.726 -122.829 31.252 1.00 24.84 ? 137 ASN C N 1 ATOM 3657 C CA . ASN B 1 79 ? 40.777 -122.068 32.491 1.00 20.90 ? 137 ASN C CA 1 ATOM 3658 C C . ASN B 1 79 ? 41.119 -120.620 32.177 1.00 15.95 ? 137 ASN C C 1 ATOM 3659 O O . ASN B 1 79 ? 42.240 -120.309 31.774 1.00 19.07 ? 137 ASN C O 1 ATOM 3660 C CB . ASN B 1 79 ? 41.804 -122.680 33.447 1.00 17.90 ? 137 ASN C CB 1 ATOM 3661 C CG . ASN B 1 79 ? 41.891 -121.945 34.773 1.00 25.55 ? 137 ASN C CG 1 ATOM 3662 O OD1 . ASN B 1 79 ? 41.140 -121.005 35.035 1.00 30.11 ? 137 ASN C OD1 1 ATOM 3663 N ND2 . ASN B 1 79 ? 42.809 -122.385 35.624 1.00 30.65 ? 137 ASN C ND2 1 ATOM 3664 N N . PHE B 1 80 ? 40.144 -119.738 32.362 1.00 16.04 ? 138 PHE C N 1 ATOM 3665 C CA . PHE B 1 80 ? 40.283 -118.354 31.936 1.00 18.58 ? 138 PHE C CA 1 ATOM 3666 C C . PHE B 1 80 ? 41.300 -117.576 32.777 1.00 16.48 ? 138 PHE C C 1 ATOM 3667 O O . PHE B 1 80 ? 41.651 -116.450 32.431 1.00 25.80 ? 138 PHE C O 1 ATOM 3668 C CB . PHE B 1 80 ? 38.914 -117.660 31.965 1.00 17.85 ? 138 PHE C CB 1 ATOM 3669 C CG . PHE B 1 80 ? 38.491 -117.175 33.325 1.00 14.66 ? 138 PHE C CG 1 ATOM 3670 C CD1 . PHE B 1 80 ? 38.389 -118.047 34.394 1.00 17.68 ? 138 PHE C CD1 1 ATOM 3671 C CD2 . PHE B 1 80 ? 38.161 -115.843 33.521 1.00 15.24 ? 138 PHE C CD2 1 ATOM 3672 C CE1 . PHE B 1 80 ? 37.989 -117.594 35.639 1.00 17.01 ? 138 PHE C CE1 1 ATOM 3673 C CE2 . PHE B 1 80 ? 37.760 -115.386 34.763 1.00 20.09 ? 138 PHE C CE2 1 ATOM 3674 C CZ . PHE B 1 80 ? 37.672 -116.263 35.822 1.00 13.78 ? 138 PHE C CZ 1 ATOM 3675 N N . LEU B 1 81 ? 41.787 -118.176 33.860 1.00 16.12 ? 139 LEU C N 1 ATOM 3676 C CA . LEU B 1 81 ? 42.821 -117.542 34.678 1.00 23.50 ? 139 LEU C CA 1 ATOM 3677 C C . LEU B 1 81 ? 44.230 -117.906 34.204 1.00 22.65 ? 139 LEU C C 1 ATOM 3678 O O . LEU B 1 81 ? 45.217 -117.417 34.751 1.00 24.03 ? 139 LEU C O 1 ATOM 3679 C CB . LEU B 1 81 ? 42.651 -117.920 36.151 1.00 19.50 ? 139 LEU C CB 1 ATOM 3680 C CG . LEU B 1 81 ? 41.410 -117.370 36.860 1.00 20.98 ? 139 LEU C CG 1 ATOM 3681 C CD1 . LEU B 1 81 ? 41.447 -117.735 38.336 1.00 24.95 ? 139 LEU C CD1 1 ATOM 3682 C CD2 . LEU B 1 81 ? 41.281 -115.863 36.698 1.00 20.73 ? 139 LEU C CD2 1 ATOM 3683 N N . GLU B 1 82 ? 44.324 -118.760 33.189 1.00 21.21 ? 140 GLU C N 1 ATOM 3684 C CA . GLU B 1 82 ? 45.605 -119.030 32.544 1.00 22.42 ? 140 GLU C CA 1 ATOM 3685 C C . GLU B 1 82 ? 46.032 -117.793 31.764 1.00 21.55 ? 140 GLU C C 1 ATOM 3686 O O . GLU B 1 82 ? 45.186 -117.006 31.338 1.00 16.01 ? 140 GLU C O 1 ATOM 3687 C CB . GLU B 1 82 ? 45.511 -120.239 31.611 0.86 21.78 ? 140 GLU C CB 1 ATOM 3688 C CG . GLU B 1 82 ? 45.220 -121.561 32.311 0.66 27.63 ? 140 GLU C CG 1 ATOM 3689 C CD . GLU B 1 82 ? 46.460 -122.226 32.884 0.61 32.43 ? 140 GLU C CD 1 ATOM 3690 O OE1 . GLU B 1 82 ? 46.347 -122.865 33.952 0.83 43.61 ? 140 GLU C OE1 1 ATOM 3691 O OE2 . GLU B 1 82 ? 47.542 -122.128 32.266 0.62 31.34 ? 140 GLU C OE2 1 ATOM 3692 N N . ASP B 1 83 ? 47.339 -117.622 31.582 1.00 22.92 ? 141 ASP C N 1 ATOM 3693 C CA . ASP B 1 83 ? 47.870 -116.488 30.831 1.00 19.03 ? 141 ASP C CA 1 ATOM 3694 C C . ASP B 1 83 ? 47.318 -116.440 29.415 1.00 22.02 ? 141 ASP C C 1 ATOM 3695 O O . ASP B 1 83 ? 47.088 -117.479 28.796 1.00 15.91 ? 141 ASP C O 1 ATOM 3696 C CB . ASP B 1 83 ? 49.400 -116.551 30.762 1.00 20.41 ? 141 ASP C CB 1 ATOM 3697 C CG . ASP B 1 83 ? 50.067 -116.272 32.100 1.00 39.91 ? 141 ASP C CG 1 ATOM 3698 O OD1 . ASP B 1 83 ? 49.475 -115.557 32.936 1.00 30.27 ? 141 ASP C OD1 1 ATOM 3699 O OD2 . ASP B 1 83 ? 51.195 -116.765 32.308 1.00 29.53 ? 141 ASP C OD2 1 ATOM 3700 N N . VAL B 1 84 ? 47.115 -115.230 28.905 1.00 17.65 ? 142 VAL C N 1 ATOM 3701 C CA . VAL B 1 84 ? 46.871 -115.054 27.481 1.00 18.29 ? 142 VAL C CA 1 ATOM 3702 C C . VAL B 1 84 ? 48.059 -115.643 26.727 1.00 23.31 ? 142 VAL C C 1 ATOM 3703 O O . VAL B 1 84 ? 49.190 -115.578 27.208 1.00 23.41 ? 142 VAL C O 1 ATOM 3704 C CB . VAL B 1 84 ? 46.684 -113.574 27.092 1.00 19.81 ? 142 VAL C CB 1 ATOM 3705 C CG1 . VAL B 1 84 ? 45.381 -113.046 27.651 1.00 19.51 ? 142 VAL C CG1 1 ATOM 3706 C CG2 . VAL B 1 84 ? 47.864 -112.728 27.567 1.00 29.09 ? 142 VAL C CG2 1 ATOM 3707 N N . PRO B 1 85 ? 47.810 -116.228 25.548 1.00 23.60 ? 143 PRO C N 1 ATOM 3708 C CA . PRO B 1 85 ? 48.881 -116.925 24.831 1.00 18.23 ? 143 PRO C CA 1 ATOM 3709 C C . PRO B 1 85 ? 49.836 -115.996 24.089 1.00 23.82 ? 143 PRO C C 1 ATOM 3710 O O . PRO B 1 85 ? 49.416 -114.962 23.571 1.00 16.04 ? 143 PRO C O 1 ATOM 3711 C CB . PRO B 1 85 ? 48.112 -117.796 23.836 1.00 20.53 ? 143 PRO C CB 1 ATOM 3712 C CG . PRO B 1 85 ? 46.886 -117.007 23.540 1.00 20.07 ? 143 PRO C CG 1 ATOM 3713 C CD . PRO B 1 85 ? 46.523 -116.317 24.833 1.00 23.04 ? 143 PRO C CD 1 ATOM 3714 N N . THR B 1 86 ? 51.111 -116.371 24.041 1.00 16.70 ? 144 THR C N 1 ATOM 3715 C CA . THR B 1 86 ? 52.065 -115.711 23.160 1.00 26.05 ? 144 THR C CA 1 ATOM 3716 C C . THR B 1 86 ? 51.806 -116.184 21.734 1.00 23.51 ? 144 THR C C 1 ATOM 3717 O O . THR B 1 86 ? 51.171 -117.217 21.529 1.00 20.49 ? 144 THR C O 1 ATOM 3718 C CB . THR B 1 86 ? 53.520 -116.021 23.551 1.00 24.82 ? 144 THR C CB 1 ATOM 3719 O OG1 . THR B 1 86 ? 53.784 -117.416 23.356 1.00 22.72 ? 144 THR C OG1 1 ATOM 3720 C CG2 . THR B 1 86 ? 53.777 -115.658 25.010 1.00 30.47 ? 144 THR C CG2 1 ATOM 3721 N N . GLU B 1 87 ? 52.289 -115.432 20.752 1.00 21.94 ? 145 GLU C N 1 ATOM 3722 C CA . GLU B 1 87 ? 52.134 -115.821 19.355 1.00 25.47 ? 145 GLU C CA 1 ATOM 3723 C C . GLU B 1 87 ? 52.796 -117.171 19.097 1.00 31.36 ? 145 GLU C C 1 ATOM 3724 O O . GLU B 1 87 ? 52.311 -117.971 18.298 1.00 26.62 ? 145 GLU C O 1 ATOM 3725 C CB . GLU B 1 87 ? 52.725 -114.749 18.433 1.00 26.84 ? 145 GLU C CB 1 ATOM 3726 C CG . GLU B 1 87 ? 52.699 -115.098 16.949 1.00 41.98 ? 145 GLU C CG 1 ATOM 3727 C CD . GLU B 1 87 ? 51.294 -115.309 16.406 1.00 53.91 ? 145 GLU C CD 1 ATOM 3728 O OE1 . GLU B 1 87 ? 51.163 -115.891 15.309 1.00 55.73 ? 145 GLU C OE1 1 ATOM 3729 O OE2 . GLU B 1 87 ? 50.321 -114.887 17.067 1.00 46.89 ? 145 GLU C OE2 1 ATOM 3730 N N . LYS B 1 88 ? 53.901 -117.419 19.791 1.00 22.12 ? 146 LYS C N 1 ATOM 3731 C CA . LYS B 1 88 ? 54.644 -118.665 19.650 1.00 25.44 ? 146 LYS C CA 1 ATOM 3732 C C . LYS B 1 88 ? 53.810 -119.866 20.103 1.00 27.73 ? 146 LYS C C 1 ATOM 3733 O O . LYS B 1 88 ? 53.725 -120.882 19.405 1.00 28.91 ? 146 LYS C O 1 ATOM 3734 C CB . LYS B 1 88 ? 55.942 -118.577 20.453 1.00 39.69 ? 146 LYS C CB 1 ATOM 3735 C CG . LYS B 1 88 ? 56.953 -119.672 20.171 1.00 45.48 ? 146 LYS C CG 1 ATOM 3736 C CD . LYS B 1 88 ? 58.330 -119.268 20.689 1.00 59.82 ? 146 LYS C CD 1 ATOM 3737 C CE . LYS B 1 88 ? 59.435 -120.161 20.146 1.00 70.08 ? 146 LYS C CE 1 ATOM 3738 N NZ . LYS B 1 88 ? 59.717 -121.324 21.030 1.00 75.19 ? 146 LYS C NZ 1 ATOM 3739 N N . GLU B 1 89 ? 53.192 -119.738 21.272 1.00 26.23 ? 147 GLU C N 1 ATOM 3740 C CA . GLU B 1 89 ? 52.327 -120.781 21.813 1.00 32.15 ? 147 GLU C CA 1 ATOM 3741 C C . GLU B 1 89 ? 51.130 -121.020 20.897 1.00 18.04 ? 147 GLU C C 1 ATOM 3742 O O . GLU B 1 89 ? 50.704 -122.157 20.689 1.00 29.92 ? 147 GLU C O 1 ATOM 3743 C CB . GLU B 1 89 ? 51.856 -120.397 23.218 1.00 27.65 ? 147 GLU C CB 1 ATOM 3744 C CG . GLU B 1 89 ? 52.980 -120.385 24.254 1.00 34.61 ? 147 GLU C CG 1 ATOM 3745 C CD . GLU B 1 89 ? 52.597 -119.709 25.564 1.00 40.34 ? 147 GLU C CD 1 ATOM 3746 O OE1 . GLU B 1 89 ? 53.253 -119.993 26.589 1.00 47.66 ? 147 GLU C OE1 1 ATOM 3747 O OE2 . GLU B 1 89 ? 51.653 -118.889 25.573 1.00 31.65 ? 147 GLU C OE2 1 ATOM 3748 N N . TYR B 1 90 ? 50.599 -119.931 20.352 1.00 18.93 ? 148 TYR C N 1 ATOM 3749 C CA . TYR B 1 90 ? 49.479 -119.989 19.421 1.00 21.82 ? 148 TYR C CA 1 ATOM 3750 C C . TYR B 1 90 ? 49.895 -120.745 18.162 1.00 31.45 ? 148 TYR C C 1 ATOM 3751 O O . TYR B 1 90 ? 49.177 -121.628 17.692 1.00 25.10 ? 148 TYR C O 1 ATOM 3752 C CB . TYR B 1 90 ? 49.005 -118.574 19.079 1.00 23.78 ? 148 TYR C CB 1 ATOM 3753 C CG . TYR B 1 90 ? 47.805 -118.492 18.157 1.00 27.51 ? 148 TYR C CG 1 ATOM 3754 C CD1 . TYR B 1 90 ? 46.896 -119.538 18.053 1.00 25.86 ? 148 TYR C CD1 1 ATOM 3755 C CD2 . TYR B 1 90 ? 47.584 -117.357 17.388 1.00 25.16 ? 148 TYR C CD2 1 ATOM 3756 C CE1 . TYR B 1 90 ? 45.801 -119.452 17.208 1.00 24.00 ? 148 TYR C CE1 1 ATOM 3757 C CE2 . TYR B 1 90 ? 46.496 -117.263 16.543 1.00 31.63 ? 148 TYR C CE2 1 ATOM 3758 C CZ . TYR B 1 90 ? 45.608 -118.311 16.456 1.00 31.72 ? 148 TYR C CZ 1 ATOM 3759 O OH . TYR B 1 90 ? 44.527 -118.208 15.611 1.00 30.17 ? 148 TYR C OH 1 ATOM 3760 N N . LYS B 1 91 ? 51.062 -120.400 17.625 1.00 27.59 ? 149 LYS C N 1 ATOM 3761 C CA . LYS B 1 91 ? 51.616 -121.111 16.478 1.00 25.59 ? 149 LYS C CA 1 ATOM 3762 C C . LYS B 1 91 ? 51.850 -122.576 16.810 1.00 28.63 ? 149 LYS C C 1 ATOM 3763 O O . LYS B 1 91 ? 51.651 -123.450 15.966 1.00 30.90 ? 149 LYS C O 1 ATOM 3764 C CB . LYS B 1 91 ? 52.931 -120.476 16.022 1.00 30.35 ? 149 LYS C CB 1 ATOM 3765 C CG . LYS B 1 91 ? 52.768 -119.179 15.255 1.00 38.07 ? 149 LYS C CG 1 ATOM 3766 C CD . LYS B 1 91 ? 54.121 -118.599 14.878 1.00 44.03 ? 149 LYS C CD 1 ATOM 3767 C CE . LYS B 1 91 ? 53.976 -117.264 14.173 1.00 53.60 ? 149 LYS C CE 1 ATOM 3768 N NZ . LYS B 1 91 ? 55.293 -116.693 13.780 1.00 66.35 ? 149 LYS C NZ 1 ATOM 3769 N N . GLN B 1 92 ? 52.288 -122.844 18.036 1.00 23.40 ? 150 GLN C N 1 ATOM 3770 C CA . GLN B 1 92 ? 52.514 -124.220 18.472 1.00 22.52 ? 150 GLN C CA 1 ATOM 3771 C C . GLN B 1 92 ? 51.220 -125.022 18.607 1.00 30.86 ? 150 GLN C C 1 ATOM 3772 O O . GLN B 1 92 ? 51.177 -126.197 18.250 1.00 27.43 ? 150 GLN C O 1 ATOM 3773 C CB . GLN B 1 92 ? 53.262 -124.248 19.811 1.00 30.53 ? 150 GLN C CB 1 ATOM 3774 C CG . GLN B 1 92 ? 54.639 -124.894 19.740 1.00 47.27 ? 150 GLN C CG 1 ATOM 3775 C CD . GLN B 1 92 ? 54.593 -126.321 19.219 1.00 59.32 ? 150 GLN C CD 1 ATOM 3776 O OE1 . GLN B 1 92 ? 53.629 -127.050 19.453 1.00 55.10 ? 150 GLN C OE1 1 ATOM 3777 N NE2 . GLN B 1 92 ? 55.637 -126.723 18.502 1.00 60.50 ? 150 GLN C NE2 1 ATOM 3778 N N . SER B 1 93 ? 50.174 -124.400 19.141 1.00 23.15 ? 151 SER C N 1 ATOM 3779 C CA . SER B 1 93 ? 48.914 -125.108 19.355 1.00 22.88 ? 151 SER C CA 1 ATOM 3780 C C . SER B 1 93 ? 48.101 -125.289 18.073 1.00 27.55 ? 151 SER C C 1 ATOM 3781 O O . SER B 1 93 ? 47.529 -126.353 17.839 1.00 27.44 ? 151 SER C O 1 ATOM 3782 C CB . SER B 1 93 ? 48.060 -124.369 20.386 1.00 15.29 ? 151 SER C CB 1 ATOM 3783 O OG . SER B 1 93 ? 47.640 -123.111 19.892 1.00 22.97 ? 151 SER C OG 1 ATOM 3784 N N . GLY B 1 94 ? 48.058 -124.252 17.245 1.00 21.24 ? 152 GLY C N 1 ATOM 3785 C CA . GLY B 1 94 ? 47.095 -124.184 16.161 1.00 25.62 ? 152 GLY C CA 1 ATOM 3786 C C . GLY B 1 94 ? 45.774 -123.694 16.721 1.00 24.27 ? 152 GLY C C 1 ATOM 3787 O O . GLY B 1 94 ? 45.663 -123.473 17.925 1.00 23.94 ? 152 GLY C O 1 ATOM 3788 N N . ASN B 1 95 ? 44.772 -123.519 15.867 1.00 23.50 ? 153 ASN C N 1 ATOM 3789 C CA . ASN B 1 95 ? 43.482 -123.017 16.329 1.00 21.88 ? 153 ASN C CA 1 ATOM 3790 C C . ASN B 1 95 ? 42.790 -124.002 17.269 1.00 19.22 ? 153 ASN C C 1 ATOM 3791 O O . ASN B 1 95 ? 42.933 -125.213 17.111 1.00 19.38 ? 153 ASN C O 1 ATOM 3792 C CB . ASN B 1 95 ? 42.564 -122.713 15.145 1.00 24.87 ? 153 ASN C CB 1 ATOM 3793 C CG . ASN B 1 95 ? 42.911 -121.411 14.451 1.00 29.09 ? 153 ASN C CG 1 ATOM 3794 O OD1 . ASN B 1 95 ? 43.654 -120.587 14.982 1.00 25.36 ? 153 ASN C OD1 1 ATOM 3795 N ND2 . ASN B 1 95 ? 42.355 -121.212 13.262 1.00 31.36 ? 153 ASN C ND2 1 ATOM 3796 N N . PRO B 1 96 ? 42.039 -123.488 18.259 1.00 13.93 ? 154 PRO C N 1 ATOM 3797 C CA . PRO B 1 96 ? 41.851 -122.074 18.594 1.00 20.69 ? 154 PRO C CA 1 ATOM 3798 C C . PRO B 1 96 ? 42.931 -121.564 19.545 1.00 20.74 ? 154 PRO C C 1 ATOM 3799 O O . PRO B 1 96 ? 43.820 -122.328 19.926 1.00 16.55 ? 154 PRO C O 1 ATOM 3800 C CB . PRO B 1 96 ? 40.483 -122.066 19.269 1.00 15.55 ? 154 PRO C CB 1 ATOM 3801 C CG . PRO B 1 96 ? 40.444 -123.371 19.976 1.00 19.51 ? 154 PRO C CG 1 ATOM 3802 C CD . PRO B 1 96 ? 41.197 -124.351 19.106 1.00 19.46 ? 154 PRO C CD 1 ATOM 3803 N N . LEU B 1 97 ? 42.844 -120.292 19.920 1.00 20.39 ? 155 LEU C N 1 ATOM 3804 C CA . LEU B 1 97 ? 43.771 -119.697 20.879 1.00 21.63 ? 155 LEU C CA 1 ATOM 3805 C C . LEU B 1 97 ? 43.909 -120.547 22.143 1.00 19.74 ? 155 LEU C C 1 ATOM 3806 O O . LEU B 1 97 ? 42.906 -120.905 22.756 1.00 18.76 ? 155 LEU C O 1 ATOM 3807 C CB . LEU B 1 97 ? 43.304 -118.293 21.269 1.00 16.04 ? 155 LEU C CB 1 ATOM 3808 C CG . LEU B 1 97 ? 43.437 -117.199 20.212 1.00 20.34 ? 155 LEU C CG 1 ATOM 3809 C CD1 . LEU B 1 97 ? 42.574 -115.999 20.580 1.00 16.16 ? 155 LEU C CD1 1 ATOM 3810 C CD2 . LEU B 1 97 ? 44.893 -116.782 20.059 1.00 23.87 ? 155 LEU C CD2 1 ATOM 3811 N N . PRO B 1 98 ? 45.149 -120.876 22.538 1.00 17.71 ? 156 PRO C N 1 ATOM 3812 C CA . PRO B 1 98 ? 45.329 -121.568 23.817 1.00 16.37 ? 156 PRO C CA 1 ATOM 3813 C C . PRO B 1 98 ? 45.322 -120.574 24.979 1.00 16.65 ? 156 PRO C C 1 ATOM 3814 O O . PRO B 1 98 ? 45.007 -119.404 24.765 1.00 19.92 ? 156 PRO C O 1 ATOM 3815 C CB . PRO B 1 98 ? 46.689 -122.244 23.656 1.00 18.66 ? 156 PRO C CB 1 ATOM 3816 C CG . PRO B 1 98 ? 47.449 -121.324 22.751 1.00 17.17 ? 156 PRO C CG 1 ATOM 3817 C CD . PRO B 1 98 ? 46.435 -120.651 21.851 1.00 17.07 ? 156 PRO C CD 1 ATOM 3818 N N . GLY B 1 99 ? 45.651 -121.030 26.183 1.00 19.27 ? 157 GLY C N 1 ATOM 3819 C CA . GLY B 1 99 ? 45.741 -120.144 27.332 1.00 21.79 ? 157 GLY C CA 1 ATOM 3820 C C . GLY B 1 99 ? 44.396 -119.633 27.821 1.00 25.61 ? 157 GLY C C 1 ATOM 3821 O O . GLY B 1 99 ? 43.362 -120.256 27.577 1.00 22.43 ? 157 GLY C O 1 ATOM 3822 N N . GLY B 1 100 ? 44.416 -118.492 28.510 1.00 19.20 ? 158 GLY C N 1 ATOM 3823 C CA . GLY B 1 100 ? 43.218 -117.916 29.095 1.00 17.12 ? 158 GLY C CA 1 ATOM 3824 C C . GLY B 1 100 ? 43.140 -116.408 28.935 1.00 15.62 ? 158 GLY C C 1 ATOM 3825 O O . GLY B 1 100 ? 43.583 -115.859 27.926 1.00 16.38 ? 158 GLY C O 1 ATOM 3826 N N . PHE B 1 101 ? 42.576 -115.744 29.941 1.00 13.97 ? 159 PHE C N 1 ATOM 3827 C CA . PHE B 1 101 ? 42.336 -114.302 29.901 1.00 13.85 ? 159 PHE C CA 1 ATOM 3828 C C . PHE B 1 101 ? 43.347 -113.496 30.726 1.00 16.68 ? 159 PHE C C 1 ATOM 3829 O O . PHE B 1 101 ? 43.330 -112.266 30.699 1.00 16.79 ? 159 PHE C O 1 ATOM 3830 C CB . PHE B 1 101 ? 40.927 -113.982 30.422 1.00 13.62 ? 159 PHE C CB 1 ATOM 3831 C CG . PHE B 1 101 ? 39.809 -114.396 29.500 1.00 16.05 ? 159 PHE C CG 1 ATOM 3832 C CD1 . PHE B 1 101 ? 40.046 -115.137 28.352 1.00 15.37 ? 159 PHE C CD1 1 ATOM 3833 C CD2 . PHE B 1 101 ? 38.508 -114.022 29.789 1.00 15.16 ? 159 PHE C CD2 1 ATOM 3834 C CE1 . PHE B 1 101 ? 39.003 -115.498 27.520 1.00 23.10 ? 159 PHE C CE1 1 ATOM 3835 C CE2 . PHE B 1 101 ? 37.469 -114.378 28.962 1.00 19.06 ? 159 PHE C CE2 1 ATOM 3836 C CZ . PHE B 1 101 ? 37.715 -115.118 27.826 1.00 21.99 ? 159 PHE C CZ 1 ATOM 3837 N N . ASN B 1 102 ? 44.214 -114.181 31.464 1.00 19.01 ? 160 ASN C N 1 ATOM 3838 C CA . ASN B 1 102 ? 45.058 -113.509 32.452 1.00 22.90 ? 160 ASN C CA 1 ATOM 3839 C C . ASN B 1 102 ? 46.186 -112.667 31.857 1.00 15.12 ? 160 ASN C C 1 ATOM 3840 O O . ASN B 1 102 ? 46.910 -113.103 30.963 1.00 16.83 ? 160 ASN C O 1 ATOM 3841 C CB . ASN B 1 102 ? 45.659 -114.534 33.412 1.00 15.57 ? 160 ASN C CB 1 ATOM 3842 C CG . ASN B 1 102 ? 46.441 -113.883 34.536 1.00 27.02 ? 160 ASN C CG 1 ATOM 3843 O OD1 . ASN B 1 102 ? 45.860 -113.294 35.445 1.00 22.11 ? 160 ASN C OD1 1 ATOM 3844 N ND2 . ASN B 1 102 ? 47.766 -113.985 34.481 1.00 24.83 ? 160 ASN C ND2 1 ATOM 3845 N N . LEU B 1 103 ? 46.327 -111.457 32.384 1.00 19.41 ? 161 LEU C N 1 ATOM 3846 C CA . LEU B 1 103 ? 47.383 -110.542 31.972 1.00 21.81 ? 161 LEU C CA 1 ATOM 3847 C C . LEU B 1 103 ? 48.754 -111.124 32.306 1.00 20.57 ? 161 LEU C C 1 ATOM 3848 O O . LEU B 1 103 ? 49.040 -111.402 33.470 1.00 23.56 ? 161 LEU C O 1 ATOM 3849 C CB . LEU B 1 103 ? 47.190 -109.192 32.661 1.00 21.24 ? 161 LEU C CB 1 ATOM 3850 C CG . LEU B 1 103 ? 48.086 -108.022 32.260 1.00 28.88 ? 161 LEU C CG 1 ATOM 3851 C CD1 . LEU B 1 103 ? 47.972 -107.711 30.777 1.00 25.43 ? 161 LEU C CD1 1 ATOM 3852 C CD2 . LEU B 1 103 ? 47.703 -106.813 33.091 1.00 23.58 ? 161 LEU C CD2 1 ATOM 3853 N N . ASN B 1 104 ? 49.593 -111.311 31.288 1.00 19.32 ? 162 ASN C N 1 ATOM 3854 C CA . ASN B 1 104 ? 50.917 -111.902 31.479 1.00 25.46 ? 162 ASN C CA 1 ATOM 3855 C C . ASN B 1 104 ? 52.054 -110.890 31.320 1.00 19.24 ? 162 ASN C C 1 ATOM 3856 O O . ASN B 1 104 ? 53.201 -111.272 31.091 1.00 21.95 ? 162 ASN C O 1 ATOM 3857 C CB . ASN B 1 104 ? 51.124 -113.063 30.499 1.00 20.93 ? 162 ASN C CB 1 ATOM 3858 C CG . ASN B 1 104 ? 51.286 -112.597 29.062 1.00 24.35 ? 162 ASN C CG 1 ATOM 3859 O OD1 . ASN B 1 104 ? 50.818 -111.523 28.685 1.00 31.36 ? 162 ASN C OD1 1 ATOM 3860 N ND2 . ASN B 1 104 ? 51.954 -113.411 28.251 1.00 38.34 ? 162 ASN C ND2 1 ATOM 3861 N N . PHE B 1 105 ? 51.739 -109.604 31.442 1.00 20.98 ? 163 PHE C N 1 ATOM 3862 C CA . PHE B 1 105 ? 52.754 -108.559 31.313 1.00 23.83 ? 163 PHE C CA 1 ATOM 3863 C C . PHE B 1 105 ? 53.668 -108.567 32.536 1.00 26.85 ? 163 PHE C C 1 ATOM 3864 O O . PHE B 1 105 ? 53.237 -108.933 33.629 1.00 22.17 ? 163 PHE C O 1 ATOM 3865 C CB . PHE B 1 105 ? 52.110 -107.178 31.153 1.00 19.75 ? 163 PHE C CB 1 ATOM 3866 C CG . PHE B 1 105 ? 51.407 -106.970 29.834 1.00 23.94 ? 163 PHE C CG 1 ATOM 3867 C CD1 . PHE B 1 105 ? 51.117 -108.034 28.992 1.00 22.77 ? 163 PHE C CD1 1 ATOM 3868 C CD2 . PHE B 1 105 ? 51.039 -105.695 29.438 1.00 25.24 ? 163 PHE C CD2 1 ATOM 3869 C CE1 . PHE B 1 105 ? 50.472 -107.826 27.788 1.00 25.21 ? 163 PHE C CE1 1 ATOM 3870 C CE2 . PHE B 1 105 ? 50.395 -105.484 28.235 1.00 30.83 ? 163 PHE C CE2 1 ATOM 3871 C CZ . PHE B 1 105 ? 50.111 -106.552 27.410 1.00 24.06 ? 163 PHE C CZ 1 ATOM 3872 N N . VAL B 1 106 ? 54.922 -108.162 32.353 1.00 25.95 ? 164 VAL C N 1 ATOM 3873 C CA . VAL B 1 106 ? 55.883 -108.128 33.456 1.00 20.00 ? 164 VAL C CA 1 ATOM 3874 C C . VAL B 1 106 ? 56.698 -106.839 33.468 1.00 23.25 ? 164 VAL C C 1 ATOM 3875 O O . VAL B 1 106 ? 56.728 -106.097 32.486 1.00 20.87 ? 164 VAL C O 1 ATOM 3876 C CB . VAL B 1 106 ? 56.862 -109.323 33.393 1.00 23.49 ? 164 VAL C CB 1 ATOM 3877 C CG1 . VAL B 1 106 ? 56.114 -110.635 33.578 1.00 21.97 ? 164 VAL C CG1 1 ATOM 3878 C CG2 . VAL B 1 106 ? 57.636 -109.323 32.081 1.00 19.63 ? 164 VAL C CG2 1 ATOM 3879 N N . THR B 1 107 ? 57.351 -106.576 34.596 1.00 24.34 ? 165 THR C N 1 ATOM 3880 C CA . THR B 1 107 ? 58.331 -105.503 34.677 1.00 24.65 ? 165 THR C CA 1 ATOM 3881 C C . THR B 1 107 ? 59.615 -105.980 34.014 1.00 20.10 ? 165 THR C C 1 ATOM 3882 O O . THR B 1 107 ? 59.785 -107.178 33.785 1.00 20.89 ? 165 THR C O 1 ATOM 3883 C CB . THR B 1 107 ? 58.639 -105.104 36.126 1.00 18.62 ? 165 THR C CB 1 ATOM 3884 O OG1 . THR B 1 107 ? 59.359 -106.166 36.762 1.00 20.90 ? 165 THR C OG1 1 ATOM 3885 C CG2 . THR B 1 107 ? 57.360 -104.813 36.901 1.00 24.06 ? 165 THR C CG2 1 ATOM 3886 N N . PRO B 1 108 ? 60.533 -105.052 33.707 1.00 21.48 ? 166 PRO C N 1 ATOM 3887 C CA . PRO B 1 108 ? 61.816 -105.469 33.124 1.00 21.74 ? 166 PRO C CA 1 ATOM 3888 C C . PRO B 1 108 ? 62.635 -106.403 34.019 1.00 20.46 ? 166 PRO C C 1 ATOM 3889 O O . PRO B 1 108 ? 63.505 -107.111 33.512 1.00 27.47 ? 166 PRO C O 1 ATOM 3890 C CB . PRO B 1 108 ? 62.536 -104.137 32.901 1.00 31.87 ? 166 PRO C CB 1 ATOM 3891 C CG . PRO B 1 108 ? 61.420 -103.171 32.667 1.00 20.88 ? 166 PRO C CG 1 ATOM 3892 C CD . PRO B 1 108 ? 60.354 -103.591 33.641 1.00 22.82 ? 166 PRO C CD 1 ATOM 3893 N N . SER B 1 109 ? 62.350 -106.417 35.318 1.00 25.07 ? 167 SER C N 1 ATOM 3894 C CA . SER B 1 109 ? 63.028 -107.323 36.239 1.00 27.35 ? 167 SER C CA 1 ATOM 3895 C C . SER B 1 109 ? 62.283 -108.652 36.374 1.00 35.68 ? 167 SER C C 1 ATOM 3896 O O . SER B 1 109 ? 62.727 -109.547 37.093 1.00 28.88 ? 167 SER C O 1 ATOM 3897 C CB . SER B 1 109 ? 63.184 -106.669 37.611 1.00 29.83 ? 167 SER C CB 1 ATOM 3898 O OG . SER B 1 109 ? 61.934 -106.230 38.111 1.00 36.21 ? 167 SER C OG 1 ATOM 3899 N N . GLY B 1 110 ? 61.147 -108.772 35.691 1.00 27.30 ? 168 GLY C N 1 ATOM 3900 C CA . GLY B 1 110 ? 60.426 -110.032 35.615 1.00 28.58 ? 168 GLY C CA 1 ATOM 3901 C C . GLY B 1 110 ? 59.304 -110.193 36.625 1.00 25.50 ? 168 GLY C C 1 ATOM 3902 O O . GLY B 1 110 ? 58.777 -111.292 36.797 1.00 36.39 ? 168 GLY C O 1 ATOM 3903 N N . GLN B 1 111 ? 58.932 -109.107 37.293 1.00 21.82 ? 169 GLN C N 1 ATOM 3904 C CA . GLN B 1 111 ? 57.821 -109.144 38.236 1.00 27.91 ? 169 GLN C CA 1 ATOM 3905 C C . GLN B 1 111 ? 56.489 -109.160 37.489 1.00 23.52 ? 169 GLN C C 1 ATOM 3906 O O . GLN B 1 111 ? 56.194 -108.257 36.706 1.00 21.66 ? 169 GLN C O 1 ATOM 3907 C CB . GLN B 1 111 ? 57.882 -107.947 39.190 1.00 23.23 ? 169 GLN C CB 1 ATOM 3908 C CG . GLN B 1 111 ? 56.719 -107.854 40.171 0.98 29.97 ? 169 GLN C CG 1 ATOM 3909 C CD . GLN B 1 111 ? 56.545 -109.111 40.999 0.83 37.01 ? 169 GLN C CD 1 ATOM 3910 O OE1 . GLN B 1 111 ? 57.428 -109.488 41.769 0.76 43.51 ? 169 GLN C OE1 1 ATOM 3911 N NE2 . GLN B 1 111 ? 55.404 -109.772 40.840 0.62 42.14 ? 169 GLN C NE2 1 ATOM 3912 N N . ARG B 1 112 ? 55.699 -110.201 37.732 1.00 26.59 ? 170 ARG C N 1 ATOM 3913 C CA . ARG B 1 112 ? 54.350 -110.300 37.182 1.00 27.92 ? 170 ARG C CA 1 ATOM 3914 C C . ARG B 1 112 ? 53.422 -109.259 37.785 1.00 22.48 ? 170 ARG C C 1 ATOM 3915 O O . ARG B 1 112 ? 53.443 -109.029 38.994 1.00 25.78 ? 170 ARG C O 1 ATOM 3916 C CB . ARG B 1 112 ? 53.759 -111.685 37.444 1.00 23.70 ? 170 ARG C CB 1 ATOM 3917 C CG . ARG B 1 112 ? 54.271 -112.803 36.563 1.00 31.48 ? 170 ARG C CG 1 ATOM 3918 C CD . ARG B 1 112 ? 53.615 -114.114 36.974 1.00 33.61 ? 170 ARG C CD 1 ATOM 3919 N NE . ARG B 1 112 ? 53.711 -115.145 35.945 1.00 41.89 ? 170 ARG C NE 1 ATOM 3920 C CZ . ARG B 1 112 ? 52.820 -115.334 34.973 1.00 48.08 ? 170 ARG C CZ 1 ATOM 3921 N NH1 . ARG B 1 112 ? 51.745 -114.560 34.871 1.00 34.89 ? 170 ARG C NH1 1 ATOM 3922 N NH2 . ARG B 1 112 ? 53.009 -116.306 34.093 1.00 36.99 ? 170 ARG C NH2 1 ATOM 3923 N N . ILE B 1 113 ? 52.597 -108.642 36.948 1.00 19.16 ? 171 ILE C N 1 ATOM 3924 C CA . ILE B 1 113 ? 51.509 -107.811 37.447 1.00 17.91 ? 171 ILE C CA 1 ATOM 3925 C C . ILE B 1 113 ? 50.326 -108.690 37.848 1.00 19.29 ? 171 ILE C C 1 ATOM 3926 O O . ILE B 1 113 ? 49.507 -108.299 38.679 1.00 23.18 ? 171 ILE C O 1 ATOM 3927 C CB . ILE B 1 113 ? 51.044 -106.774 36.408 1.00 18.55 ? 171 ILE C CB 1 ATOM 3928 C CG1 . ILE B 1 113 ? 50.007 -105.840 37.035 1.00 21.12 ? 171 ILE C CG1 1 ATOM 3929 C CG2 . ILE B 1 113 ? 50.471 -107.464 35.170 1.00 28.52 ? 171 ILE C CG2 1 ATOM 3930 C CD1 . ILE B 1 113 ? 49.703 -104.618 36.213 1.00 26.04 ? 171 ILE C CD1 1 ATOM 3931 N N . SER B 1 114 ? 50.240 -109.878 37.253 1.00 21.86 ? 172 SER C N 1 ATOM 3932 C CA . SER B 1 114 ? 49.130 -110.789 37.525 1.00 21.14 ? 172 SER C CA 1 ATOM 3933 C C . SER B 1 114 ? 49.511 -112.248 37.258 1.00 15.54 ? 172 SER C C 1 ATOM 3934 O O . SER B 1 114 ? 50.069 -112.556 36.203 1.00 22.62 ? 172 SER C O 1 ATOM 3935 C CB . SER B 1 114 ? 47.917 -110.411 36.674 1.00 20.64 ? 172 SER C CB 1 ATOM 3936 O OG . SER B 1 114 ? 46.831 -111.283 36.924 1.00 23.02 ? 172 SER C OG 1 ATOM 3937 N N . PRO B 1 115 ? 49.208 -113.156 38.203 1.00 24.10 ? 173 PRO C N 1 ATOM 3938 C CA . PRO B 1 115 ? 48.580 -112.927 39.512 1.00 28.48 ? 173 PRO C CA 1 ATOM 3939 C C . PRO B 1 115 ? 49.509 -112.225 40.498 1.00 23.90 ? 173 PRO C C 1 ATOM 3940 O O . PRO B 1 115 ? 50.720 -112.438 40.455 1.00 29.65 ? 173 PRO C O 1 ATOM 3941 C CB . PRO B 1 115 ? 48.247 -114.341 39.995 1.00 20.97 ? 173 PRO C CB 1 ATOM 3942 C CG . PRO B 1 115 ? 49.213 -115.217 39.297 1.00 24.51 ? 173 PRO C CG 1 ATOM 3943 C CD . PRO B 1 115 ? 49.436 -114.591 37.955 1.00 24.48 ? 173 PRO C CD 1 ATOM 3944 N N . PHE B 1 116 ? 48.936 -111.402 41.372 1.00 24.89 ? 174 PHE C N 1 ATOM 3945 C CA . PHE B 1 116 ? 49.710 -110.621 42.331 1.00 29.37 ? 174 PHE C CA 1 ATOM 3946 C C . PHE B 1 116 ? 49.333 -110.991 43.766 1.00 25.43 ? 174 PHE C C 1 ATOM 3947 O O . PHE B 1 116 ? 48.169 -110.879 44.144 1.00 23.46 ? 174 PHE C O 1 ATOM 3948 C CB . PHE B 1 116 ? 49.485 -109.129 42.100 1.00 22.25 ? 174 PHE C CB 1 ATOM 3949 C CG . PHE B 1 116 ? 50.566 -108.259 42.675 1.00 28.30 ? 174 PHE C CG 1 ATOM 3950 C CD1 . PHE B 1 116 ? 51.747 -108.052 41.979 1.00 26.08 ? 174 PHE C CD1 1 ATOM 3951 C CD2 . PHE B 1 116 ? 50.406 -107.650 43.908 1.00 27.69 ? 174 PHE C CD2 1 ATOM 3952 C CE1 . PHE B 1 116 ? 52.748 -107.253 42.503 1.00 32.40 ? 174 PHE C CE1 1 ATOM 3953 C CE2 . PHE B 1 116 ? 51.405 -106.849 44.437 1.00 28.61 ? 174 PHE C CE2 1 ATOM 3954 C CZ . PHE B 1 116 ? 52.575 -106.651 43.732 1.00 30.94 ? 174 PHE C CZ 1 ATOM 3955 N N . PRO B 1 117 ? 50.315 -111.430 44.573 1.00 25.22 ? 175 PRO C N 1 ATOM 3956 C CA . PRO B 1 117 ? 49.988 -111.860 45.939 1.00 23.90 ? 175 PRO C CA 1 ATOM 3957 C C . PRO B 1 117 ? 49.472 -110.732 46.827 1.00 21.75 ? 175 PRO C C 1 ATOM 3958 O O . PRO B 1 117 ? 49.983 -109.614 46.783 1.00 25.31 ? 175 PRO C O 1 ATOM 3959 C CB . PRO B 1 117 ? 51.320 -112.404 46.471 1.00 35.69 ? 175 PRO C CB 1 ATOM 3960 C CG . PRO B 1 117 ? 52.363 -111.802 45.611 1.00 32.93 ? 175 PRO C CG 1 ATOM 3961 C CD . PRO B 1 117 ? 51.746 -111.610 44.268 1.00 28.30 ? 175 PRO C CD 1 ATOM 3962 N N . MET B 1 118 ? 48.458 -111.042 47.627 1.00 22.67 ? 176 MET C N 1 ATOM 3963 C CA . MET B 1 118 ? 47.856 -110.070 48.529 1.00 27.33 ? 176 MET C CA 1 ATOM 3964 C C . MET B 1 118 ? 48.864 -109.599 49.574 1.00 30.35 ? 176 MET C C 1 ATOM 3965 O O . MET B 1 118 ? 48.772 -108.482 50.081 1.00 24.12 ? 176 MET C O 1 ATOM 3966 C CB . MET B 1 118 ? 46.630 -110.678 49.214 1.00 30.40 ? 176 MET C CB 1 ATOM 3967 C CG . MET B 1 118 ? 45.875 -109.724 50.132 1.00 23.78 ? 176 MET C CG 1 ATOM 3968 S SD . MET B 1 118 ? 45.394 -108.178 49.337 1.00 31.50 ? 176 MET C SD 1 ATOM 3969 C CE . MET B 1 118 ? 44.547 -108.777 47.873 1.00 26.82 ? 176 MET C CE 1 ATOM 3970 N N . GLU B 1 119 ? 49.828 -110.458 49.887 1.00 25.66 ? 177 GLU C N 1 ATOM 3971 C CA . GLU B 1 119 ? 50.832 -110.149 50.898 1.00 42.88 ? 177 GLU C CA 1 ATOM 3972 C C . GLU B 1 119 ? 51.682 -108.937 50.515 1.00 32.77 ? 177 GLU C C 1 ATOM 3973 O O . GLU B 1 119 ? 52.214 -108.251 51.387 1.00 39.54 ? 177 GLU C O 1 ATOM 3974 C CB . GLU B 1 119 ? 51.734 -111.361 51.138 1.00 42.46 ? 177 GLU C CB 1 ATOM 3975 C CG . GLU B 1 119 ? 51.051 -112.509 51.878 1.00 64.03 ? 177 GLU C CG 1 ATOM 3976 C CD . GLU B 1 119 ? 50.156 -113.362 50.989 1.00 92.66 ? 177 GLU C CD 1 ATOM 3977 O OE1 . GLU B 1 119 ? 49.553 -114.325 51.511 1.00 77.66 ? 177 GLU C OE1 1 ATOM 3978 O OE2 . GLU B 1 119 ? 50.052 -113.078 49.776 1.00 57.26 ? 177 GLU C OE2 1 ATOM 3979 N N . LEU B 1 120 ? 51.803 -108.674 49.216 1.00 30.46 ? 178 LEU C N 1 ATOM 3980 C CA . LEU B 1 120 ? 52.582 -107.536 48.733 1.00 25.87 ? 178 LEU C CA 1 ATOM 3981 C C . LEU B 1 120 ? 51.739 -106.265 48.605 1.00 32.96 ? 178 LEU C C 1 ATOM 3982 O O . LEU B 1 120 ? 52.275 -105.188 48.341 1.00 41.86 ? 178 LEU C O 1 ATOM 3983 C CB . LEU B 1 120 ? 53.225 -107.866 47.381 1.00 33.14 ? 178 LEU C CB 1 ATOM 3984 C CG . LEU B 1 120 ? 54.315 -108.944 47.364 1.00 34.52 ? 178 LEU C CG 1 ATOM 3985 C CD1 . LEU B 1 120 ? 54.850 -109.120 45.951 1.00 39.56 ? 178 LEU C CD1 1 ATOM 3986 C CD2 . LEU B 1 120 ? 55.453 -108.610 48.317 1.00 36.76 ? 178 LEU C CD2 1 ATOM 3987 N N . LEU B 1 121 ? 50.429 -106.390 48.798 1.00 29.74 ? 179 LEU C N 1 ATOM 3988 C CA . LEU B 1 121 ? 49.518 -105.252 48.686 1.00 27.50 ? 179 LEU C CA 1 ATOM 3989 C C . LEU B 1 121 ? 49.140 -104.664 50.044 1.00 28.81 ? 179 LEU C C 1 ATOM 3990 O O . LEU B 1 121 ? 48.830 -103.477 50.148 1.00 35.84 ? 179 LEU C O 1 ATOM 3991 C CB . LEU B 1 121 ? 48.241 -105.666 47.950 1.00 34.62 ? 179 LEU C CB 1 ATOM 3992 C CG . LEU B 1 121 ? 48.349 -105.992 46.461 1.00 32.89 ? 179 LEU C CG 1 ATOM 3993 C CD1 . LEU B 1 121 ? 47.004 -106.476 45.941 1.00 28.41 ? 179 LEU C CD1 1 ATOM 3994 C CD2 . LEU B 1 121 ? 48.816 -104.785 45.673 1.00 28.49 ? 179 LEU C CD2 1 ATOM 3995 N N . GLU B 1 122 ? 49.164 -105.495 51.079 1.00 30.11 ? 180 GLU C N 1 ATOM 3996 C CA . GLU B 1 122 ? 48.615 -105.113 52.379 1.00 48.31 ? 180 GLU C CA 1 ATOM 3997 C C . GLU B 1 122 ? 49.599 -104.333 53.256 1.00 43.56 ? 180 GLU C C 1 ATOM 3998 O O . GLU B 1 122 ? 49.269 -103.967 54.385 1.00 57.76 ? 180 GLU C O 1 ATOM 3999 C CB . GLU B 1 122 ? 48.125 -106.360 53.124 1.00 32.10 ? 180 GLU C CB 1 ATOM 4000 C CG . GLU B 1 122 ? 49.179 -107.438 53.352 1.00 46.97 ? 180 GLU C CG 1 ATOM 4001 C CD . GLU B 1 122 ? 48.578 -108.733 53.873 1.00 63.76 ? 180 GLU C CD 1 ATOM 4002 O OE1 . GLU B 1 122 ? 47.333 -108.832 53.933 1.00 61.39 ? 180 GLU C OE1 1 ATOM 4003 O OE2 . GLU B 1 122 ? 49.348 -109.654 54.221 1.00 60.12 ? 180 GLU C OE2 1 ATOM 4004 N N . LYS B 1 123 ? 50.799 -104.080 52.737 1.00 41.30 ? 181 LYS C N 1 ATOM 4005 C CA . LYS B 1 123 ? 51.763 -103.212 53.410 1.00 58.86 ? 181 LYS C CA 1 ATOM 4006 C C . LYS B 1 123 ? 52.401 -102.246 52.412 1.00 62.79 ? 181 LYS C C 1 ATOM 4007 O O . LYS B 1 123 ? 53.536 -101.803 52.594 1.00 60.57 ? 181 LYS C O 1 ATOM 4008 C CB . LYS B 1 123 ? 52.840 -104.041 54.115 1.00 78.92 ? 181 LYS C CB 1 ATOM 4009 C CG . LYS B 1 123 ? 52.349 -104.750 55.372 1.00 80.07 ? 181 LYS C CG 1 ATOM 4010 C CD . LYS B 1 123 ? 53.480 -105.462 56.109 1.00 91.79 ? 181 LYS C CD 1 ATOM 4011 C CE . LYS B 1 123 ? 54.237 -106.425 55.206 1.00 104.40 ? 181 LYS C CE 1 ATOM 4012 N NZ . LYS B 1 123 ? 53.322 -107.295 54.414 1.00 83.90 ? 181 LYS C NZ 1 ATOM 4013 N N . ASN B 1 124 ? 51.655 -101.924 51.359 1.00 55.38 ? 182 ASN C N 1 ATOM 4014 C CA . ASN B 1 124 ? 52.104 -100.979 50.345 1.00 38.16 ? 182 ASN C CA 1 ATOM 4015 C C . ASN B 1 124 ? 51.451 -99.616 50.554 1.00 44.81 ? 182 ASN C C 1 ATOM 4016 O O . ASN B 1 124 ? 50.254 -99.530 50.825 1.00 39.68 ? 182 ASN C O 1 ATOM 4017 C CB . ASN B 1 124 ? 51.786 -101.508 48.947 1.00 40.50 ? 182 ASN C CB 1 ATOM 4018 C CG . ASN B 1 124 ? 52.521 -100.756 47.860 1.00 37.15 ? 182 ASN C CG 1 ATOM 4019 O OD1 . ASN B 1 124 ? 52.137 -99.650 47.484 1.00 46.65 ? 182 ASN C OD1 1 ATOM 4020 N ND2 . ASN B 1 124 ? 53.587 -101.358 47.344 1.00 43.66 ? 182 ASN C ND2 1 ATOM 4021 N N . SER B 1 125 ? 52.239 -98.555 50.422 1.00 42.25 ? 183 SER C N 1 ATOM 4022 C CA . SER B 1 125 ? 51.766 -97.209 50.730 1.00 43.36 ? 183 SER C CA 1 ATOM 4023 C C . SER B 1 125 ? 50.814 -96.657 49.668 1.00 36.09 ? 183 SER C C 1 ATOM 4024 O O . SER B 1 125 ? 50.062 -95.718 49.933 1.00 44.18 ? 183 SER C O 1 ATOM 4025 C CB . SER B 1 125 ? 52.956 -96.262 50.901 1.00 60.53 ? 183 SER C CB 1 ATOM 4026 O OG . SER B 1 125 ? 53.809 -96.302 49.770 1.00 57.54 ? 183 SER C OG 1 ATOM 4027 N N . ASN B 1 126 ? 50.847 -97.237 48.472 1.00 42.84 ? 184 ASN C N 1 ATOM 4028 C CA . ASN B 1 126 ? 49.955 -96.815 47.393 1.00 39.33 ? 184 ASN C CA 1 ATOM 4029 C C . ASN B 1 126 ? 48.607 -97.540 47.421 1.00 31.39 ? 184 ASN C C 1 ATOM 4030 O O . ASN B 1 126 ? 47.733 -97.267 46.598 1.00 44.05 ? 184 ASN C O 1 ATOM 4031 C CB . ASN B 1 126 ? 50.635 -97.030 46.040 1.00 40.25 ? 184 ASN C CB 1 ATOM 4032 C CG . ASN B 1 126 ? 51.657 -95.955 45.727 1.00 49.69 ? 184 ASN C CG 1 ATOM 4033 O OD1 . ASN B 1 126 ? 51.350 -94.763 45.761 1.00 46.24 ? 184 ASN C OD1 1 ATOM 4034 N ND2 . ASN B 1 126 ? 52.884 -96.370 45.434 1.00 42.26 ? 184 ASN C ND2 1 ATOM 4035 N N . ILE B 1 127 ? 48.447 -98.455 48.374 1.00 34.73 ? 185 ILE C N 1 ATOM 4036 C CA . ILE B 1 127 ? 47.206 -99.210 48.538 1.00 30.08 ? 185 ILE C CA 1 ATOM 4037 C C . ILE B 1 127 ? 46.561 -98.876 49.881 1.00 24.23 ? 185 ILE C C 1 ATOM 4038 O O . ILE B 1 127 ? 47.053 -99.288 50.931 1.00 30.88 ? 185 ILE C O 1 ATOM 4039 C CB . ILE B 1 127 ? 47.461 -100.728 48.451 1.00 29.87 ? 185 ILE C CB 1 ATOM 4040 C CG1 . ILE B 1 127 ? 48.100 -101.094 47.105 1.00 28.66 ? 185 ILE C CG1 1 ATOM 4041 C CG2 . ILE B 1 127 ? 46.172 -101.507 48.665 1.00 35.50 ? 185 ILE C CG2 1 ATOM 4042 C CD1 . ILE B 1 127 ? 47.254 -100.755 45.889 1.00 33.72 ? 185 ILE C CD1 1 ATOM 4043 N N . LYS B 1 128 ? 45.450 -98.145 49.834 1.00 25.90 ? 186 LYS C N 1 ATOM 4044 C CA . LYS B 1 128 ? 44.814 -97.621 51.040 1.00 37.08 ? 186 LYS C CA 1 ATOM 4045 C C . LYS B 1 128 ? 43.515 -98.335 51.416 1.00 41.50 ? 186 LYS C C 1 ATOM 4046 O O . LYS B 1 128 ? 42.872 -97.969 52.400 1.00 39.35 ? 186 LYS C O 1 ATOM 4047 C CB . LYS B 1 128 ? 44.532 -96.127 50.862 1.00 44.43 ? 186 LYS C CB 1 ATOM 4048 C CG . LYS B 1 128 ? 45.786 -95.281 50.721 1.00 56.04 ? 186 LYS C CG 1 ATOM 4049 C CD . LYS B 1 128 ? 45.452 -93.863 50.284 1.00 62.85 ? 186 LYS C CD 1 ATOM 4050 C CE . LYS B 1 128 ? 46.679 -93.128 49.767 1.00 64.91 ? 186 LYS C CE 1 ATOM 4051 N NZ . LYS B 1 128 ? 46.413 -92.485 48.450 1.00 83.97 ? 186 LYS C NZ 1 ATOM 4052 N N . ALA B 1 129 ? 43.127 -99.344 50.643 1.00 33.21 ? 187 ALA C N 1 ATOM 4053 C CA . ALA B 1 129 ? 41.887 -100.068 50.916 1.00 31.48 ? 187 ALA C CA 1 ATOM 4054 C C . ALA B 1 129 ? 41.961 -100.789 52.260 1.00 27.33 ? 187 ALA C C 1 ATOM 4055 O O . ALA B 1 129 ? 43.034 -101.217 52.686 1.00 29.25 ? 187 ALA C O 1 ATOM 4056 C CB . ALA B 1 129 ? 41.590 -101.057 49.800 1.00 29.13 ? 187 ALA C CB 1 ATOM 4057 N N . SER B 1 130 ? 40.813 -100.923 52.919 1.00 28.21 ? 188 SER C N 1 ATOM 4058 C CA . SER B 1 130 ? 40.750 -101.495 54.263 1.00 25.61 ? 188 SER C CA 1 ATOM 4059 C C . SER B 1 130 ? 40.563 -103.016 54.277 1.00 33.63 ? 188 SER C C 1 ATOM 4060 O O . SER B 1 130 ? 40.690 -103.647 55.328 1.00 30.89 ? 188 SER C O 1 ATOM 4061 C CB . SER B 1 130 ? 39.614 -100.841 55.051 1.00 38.60 ? 188 SER C CB 1 ATOM 4062 O OG . SER B 1 130 ? 38.365 -101.056 54.416 1.00 46.10 ? 188 SER C OG 1 ATOM 4063 N N . THR B 1 131 ? 40.255 -103.595 53.120 1.00 28.46 ? 189 THR C N 1 ATOM 4064 C CA . THR B 1 131 ? 40.051 -105.040 53.004 1.00 22.23 ? 189 THR C CA 1 ATOM 4065 C C . THR B 1 131 ? 40.813 -105.603 51.814 1.00 17.72 ? 189 THR C C 1 ATOM 4066 O O . THR B 1 131 ? 41.083 -104.887 50.851 1.00 27.04 ? 189 THR C O 1 ATOM 4067 C CB . THR B 1 131 ? 38.569 -105.389 52.841 1.00 27.32 ? 189 THR C CB 1 ATOM 4068 O OG1 . THR B 1 131 ? 38.091 -104.864 51.597 1.00 28.78 ? 189 THR C OG1 1 ATOM 4069 C CG2 . THR B 1 131 ? 37.750 -104.811 53.986 1.00 24.87 ? 189 THR C CG2 1 ATOM 4070 N N . ASP B 1 132 ? 41.136 -106.891 51.878 1.00 18.35 ? 190 ASP C N 1 ATOM 4071 C CA . ASP B 1 132 ? 41.900 -107.552 50.824 1.00 26.20 ? 190 ASP C CA 1 ATOM 4072 C C . ASP B 1 132 ? 41.225 -107.434 49.454 1.00 21.47 ? 190 ASP C C 1 ATOM 4073 O O . ASP B 1 132 ? 41.885 -107.155 48.446 1.00 25.07 ? 190 ASP C O 1 ATOM 4074 C CB . ASP B 1 132 ? 42.111 -109.029 51.171 1.00 22.94 ? 190 ASP C CB 1 ATOM 4075 C CG . ASP B 1 132 ? 43.018 -109.228 52.376 1.00 41.34 ? 190 ASP C CG 1 ATOM 4076 O OD1 . ASP B 1 132 ? 43.731 -108.276 52.759 1.00 29.94 ? 190 ASP C OD1 1 ATOM 4077 O OD2 . ASP B 1 132 ? 43.027 -110.344 52.935 1.00 35.52 ? 190 ASP C OD2 1 ATOM 4078 N N . LEU B 1 133 ? 39.912 -107.649 49.419 1.00 26.20 ? 191 LEU C N 1 ATOM 4079 C CA . LEU B 1 133 ? 39.155 -107.523 48.175 1.00 31.32 ? 191 LEU C CA 1 ATOM 4080 C C . LEU B 1 133 ? 39.246 -106.092 47.655 1.00 18.27 ? 191 LEU C C 1 ATOM 4081 O O . LEU B 1 133 ? 39.488 -105.860 46.465 1.00 20.49 ? 191 LEU C O 1 ATOM 4082 C CB . LEU B 1 133 ? 37.690 -107.918 48.382 1.00 24.95 ? 191 LEU C CB 1 ATOM 4083 C CG . LEU B 1 133 ? 36.784 -107.827 47.148 1.00 25.07 ? 191 LEU C CG 1 ATOM 4084 C CD1 . LEU B 1 133 ? 37.336 -108.648 45.988 1.00 23.63 ? 191 LEU C CD1 1 ATOM 4085 C CD2 . LEU B 1 133 ? 35.372 -108.283 47.489 1.00 20.01 ? 191 LEU C CD2 1 ATOM 4086 N N . GLY B 1 134 ? 39.059 -105.137 48.561 1.00 21.21 ? 192 GLY C N 1 ATOM 4087 C CA . GLY B 1 134 ? 39.199 -103.731 48.232 1.00 26.98 ? 192 GLY C CA 1 ATOM 4088 C C . GLY B 1 134 ? 40.595 -103.414 47.728 1.00 12.98 ? 192 GLY C C 1 ATOM 4089 O O . GLY B 1 134 ? 40.769 -102.570 46.847 1.00 24.52 ? 192 GLY C O 1 ATOM 4090 N N . ARG B 1 135 ? 41.592 -104.096 48.285 1.00 16.40 ? 193 ARG C N 1 ATOM 4091 C CA . ARG B 1 135 ? 42.979 -103.887 47.882 1.00 22.21 ? 193 ARG C CA 1 ATOM 4092 C C . ARG B 1 135 ? 43.217 -104.434 46.478 1.00 24.68 ? 193 ARG C C 1 ATOM 4093 O O . ARG B 1 135 ? 43.895 -103.803 45.665 1.00 20.83 ? 193 ARG C O 1 ATOM 4094 C CB . ARG B 1 135 ? 43.940 -104.541 48.878 1.00 19.51 ? 193 ARG C CB 1 ATOM 4095 C CG . ARG B 1 135 ? 44.034 -103.808 50.217 1.00 19.35 ? 193 ARG C CG 1 ATOM 4096 C CD . ARG B 1 135 ? 44.956 -104.516 51.201 1.00 32.77 ? 193 ARG C CD 1 ATOM 4097 N NE . ARG B 1 135 ? 44.950 -103.859 52.511 1.00 33.58 ? 193 ARG C NE 1 ATOM 4098 C CZ . ARG B 1 135 ? 44.385 -104.345 53.616 1.00 35.78 ? 193 ARG C CZ 1 ATOM 4099 N NH1 . ARG B 1 135 ? 43.771 -105.523 53.617 1.00 29.34 ? 193 ARG C NH1 1 ATOM 4100 N NH2 . ARG B 1 135 ? 44.445 -103.647 54.741 1.00 44.07 ? 193 ARG C NH2 1 ATOM 4101 N N . CYS B 1 136 ? 42.664 -105.608 46.193 1.00 22.78 ? 194 CYS C N 1 ATOM 4102 C CA . CYS B 1 136 ? 42.715 -106.154 44.838 1.00 20.64 ? 194 CYS C CA 1 ATOM 4103 C C . CYS B 1 136 ? 42.027 -105.214 43.842 1.00 17.13 ? 194 CYS C C 1 ATOM 4104 O O . CYS B 1 136 ? 42.580 -104.880 42.784 1.00 20.28 ? 194 CYS C O 1 ATOM 4105 C CB . CYS B 1 136 ? 42.065 -107.539 44.796 1.00 26.71 ? 194 CYS C CB 1 ATOM 4106 S SG . CYS B 1 136 ? 42.168 -108.366 43.190 1.00 29.45 ? 194 CYS C SG 1 ATOM 4107 N N . ALA B 1 137 ? 40.819 -104.779 44.185 1.00 18.75 ? 195 ALA C N 1 ATOM 4108 C CA . ALA B 1 137 ? 40.075 -103.859 43.331 1.00 20.90 ? 195 ALA C CA 1 ATOM 4109 C C . ALA B 1 137 ? 40.834 -102.553 43.108 1.00 20.15 ? 195 ALA C C 1 ATOM 4110 O O . ALA B 1 137 ? 40.883 -102.029 41.993 1.00 19.73 ? 195 ALA C O 1 ATOM 4111 C CB . ALA B 1 137 ? 38.728 -103.571 43.931 1.00 17.45 ? 195 ALA C CB 1 ATOM 4112 N N . GLU B 1 138 ? 41.410 -102.024 44.181 1.00 21.07 ? 196 GLU C N 1 ATOM 4113 C CA . GLU B 1 138 ? 42.198 -100.803 44.105 1.00 21.15 ? 196 GLU C CA 1 ATOM 4114 C C . GLU B 1 138 ? 43.418 -101.021 43.220 1.00 19.54 ? 196 GLU C C 1 ATOM 4115 O O . GLU B 1 138 ? 43.779 -100.163 42.416 1.00 19.80 ? 196 GLU C O 1 ATOM 4116 C CB . GLU B 1 138 ? 42.625 -100.360 45.503 1.00 26.20 ? 196 GLU C CB 1 ATOM 4117 C CG . GLU B 1 138 ? 43.454 -99.091 45.530 1.00 32.88 ? 196 GLU C CG 1 ATOM 4118 C CD . GLU B 1 138 ? 43.799 -98.666 46.942 1.00 44.46 ? 196 GLU C CD 1 ATOM 4119 O OE1 . GLU B 1 138 ? 44.272 -97.525 47.127 1.00 40.36 ? 196 GLU C OE1 1 ATOM 4120 O OE2 . GLU B 1 138 ? 43.596 -99.479 47.869 1.00 33.05 ? 196 GLU C OE2 1 ATOM 4121 N N . PHE B 1 139 ? 44.049 -102.178 43.383 1.00 19.50 ? 197 PHE C N 1 ATOM 4122 C CA . PHE B 1 139 ? 45.170 -102.570 42.544 1.00 17.15 ? 197 PHE C CA 1 ATOM 4123 C C . PHE B 1 139 ? 44.753 -102.564 41.080 1.00 27.17 ? 197 PHE C C 1 ATOM 4124 O O . PHE B 1 139 ? 45.487 -102.071 40.222 1.00 20.39 ? 197 PHE C O 1 ATOM 4125 C CB . PHE B 1 139 ? 45.680 -103.950 42.962 1.00 20.54 ? 197 PHE C CB 1 ATOM 4126 C CG . PHE B 1 139 ? 46.863 -104.434 42.178 1.00 22.43 ? 197 PHE C CG 1 ATOM 4127 C CD1 . PHE B 1 139 ? 48.118 -103.888 42.379 1.00 24.49 ? 197 PHE C CD1 1 ATOM 4128 C CD2 . PHE B 1 139 ? 46.724 -105.461 41.260 1.00 27.01 ? 197 PHE C CD2 1 ATOM 4129 C CE1 . PHE B 1 139 ? 49.210 -104.344 41.665 1.00 24.08 ? 197 PHE C CE1 1 ATOM 4130 C CE2 . PHE B 1 139 ? 47.809 -105.921 40.544 1.00 26.93 ? 197 PHE C CE2 1 ATOM 4131 C CZ . PHE B 1 139 ? 49.055 -105.362 40.748 1.00 27.06 ? 197 PHE C CZ 1 ATOM 4132 N N . ALA B 1 140 ? 43.572 -103.104 40.793 1.00 24.14 ? 198 ALA C N 1 ATOM 4133 C CA . ALA B 1 140 ? 43.039 -103.044 39.432 1.00 21.33 ? 198 ALA C CA 1 ATOM 4134 C C . ALA B 1 140 ? 42.746 -101.615 38.975 1.00 16.45 ? 198 ALA C C 1 ATOM 4135 O O . ALA B 1 140 ? 43.036 -101.256 37.836 1.00 15.97 ? 198 ALA C O 1 ATOM 4136 C CB . ALA B 1 140 ? 41.781 -103.886 39.320 1.00 19.09 ? 198 ALA C CB 1 ATOM 4137 N N . PHE B 1 141 ? 42.161 -100.798 39.845 1.00 18.77 ? 199 PHE C N 1 ATOM 4138 C CA . PHE B 1 141 ? 41.824 -99.432 39.452 1.00 17.27 ? 199 PHE C CA 1 ATOM 4139 C C . PHE B 1 141 ? 43.070 -98.604 39.143 1.00 22.67 ? 199 PHE C C 1 ATOM 4140 O O . PHE B 1 141 ? 43.028 -97.691 38.317 1.00 21.19 ? 199 PHE C O 1 ATOM 4141 C CB . PHE B 1 141 ? 41.008 -98.737 40.538 1.00 19.70 ? 199 PHE C CB 1 ATOM 4142 C CG . PHE B 1 141 ? 40.595 -97.341 40.175 1.00 21.97 ? 199 PHE C CG 1 ATOM 4143 C CD1 . PHE B 1 141 ? 39.563 -97.123 39.278 1.00 19.66 ? 199 PHE C CD1 1 ATOM 4144 C CD2 . PHE B 1 141 ? 41.247 -96.249 40.721 1.00 27.66 ? 199 PHE C CD2 1 ATOM 4145 C CE1 . PHE B 1 141 ? 39.183 -95.840 38.935 1.00 19.23 ? 199 PHE C CE1 1 ATOM 4146 C CE2 . PHE B 1 141 ? 40.872 -94.963 40.383 1.00 22.95 ? 199 PHE C CE2 1 ATOM 4147 C CZ . PHE B 1 141 ? 39.839 -94.757 39.489 1.00 24.96 ? 199 PHE C CZ 1 ATOM 4148 N N . LYS B 1 142 ? 44.178 -98.932 39.798 1.00 25.30 ? 200 LYS C N 1 ATOM 4149 C CA . LYS B 1 142 ? 45.421 -98.199 39.598 1.00 31.75 ? 200 LYS C CA 1 ATOM 4150 C C . LYS B 1 142 ? 46.269 -98.857 38.514 1.00 26.14 ? 200 LYS C C 1 ATOM 4151 O O . LYS B 1 142 ? 47.498 -98.791 38.534 1.00 27.06 ? 200 LYS C O 1 ATOM 4152 C CB . LYS B 1 142 ? 46.180 -98.094 40.921 1.00 25.07 ? 200 LYS C CB 1 ATOM 4153 C CG . LYS B 1 142 ? 45.543 -97.075 41.853 1.00 28.64 ? 200 LYS C CG 1 ATOM 4154 C CD . LYS B 1 142 ? 46.092 -97.128 43.264 1.00 36.72 ? 200 LYS C CD 1 ATOM 4155 C CE . LYS B 1 142 ? 45.568 -95.951 44.076 1.00 33.95 ? 200 LYS C CE 1 ATOM 4156 N NZ . LYS B 1 142 ? 45.735 -96.133 45.543 1.00 34.68 ? 200 LYS C NZ 1 ATOM 4157 N N . THR B 1 143 ? 45.582 -99.489 37.567 1.00 28.33 ? 201 THR C N 1 ATOM 4158 C CA . THR B 1 143 ? 46.201 -100.057 36.381 1.00 20.77 ? 201 THR C CA 1 ATOM 4159 C C . THR B 1 143 ? 45.483 -99.488 35.165 1.00 25.71 ? 201 THR C C 1 ATOM 4160 O O . THR B 1 143 ? 44.264 -99.611 35.054 1.00 29.64 ? 201 THR C O 1 ATOM 4161 C CB . THR B 1 143 ? 46.119 -101.596 36.364 1.00 24.77 ? 201 THR C CB 1 ATOM 4162 O OG1 . THR B 1 143 ? 46.757 -102.128 37.531 1.00 30.09 ? 201 THR C OG1 1 ATOM 4163 C CG2 . THR B 1 143 ? 46.796 -102.160 35.124 1.00 24.31 ? 201 THR C CG2 1 ATOM 4164 N N . VAL B 1 144 ? 46.230 -98.851 34.269 1.00 23.90 ? 202 VAL C N 1 ATOM 4165 C CA . VAL B 1 144 ? 45.645 -98.276 33.064 1.00 20.86 ? 202 VAL C CA 1 ATOM 4166 C C . VAL B 1 144 ? 46.459 -98.641 31.834 1.00 23.77 ? 202 VAL C C 1 ATOM 4167 O O . VAL B 1 144 ? 47.663 -98.886 31.917 1.00 26.99 ? 202 VAL C O 1 ATOM 4168 C CB . VAL B 1 144 ? 45.537 -96.736 33.155 1.00 26.78 ? 202 VAL C CB 1 ATOM 4169 C CG1 . VAL B 1 144 ? 44.672 -96.330 34.340 1.00 29.78 ? 202 VAL C CG1 1 ATOM 4170 C CG2 . VAL B 1 144 ? 46.918 -96.097 33.254 1.00 36.56 ? 202 VAL C CG2 1 ATOM 4171 N N . ALA B 1 145 ? 45.786 -98.682 30.691 1.00 21.50 ? 203 ALA C N 1 ATOM 4172 C CA . ALA B 1 145 ? 46.456 -98.906 29.424 1.00 27.98 ? 203 ALA C CA 1 ATOM 4173 C C . ALA B 1 145 ? 47.208 -97.650 29.002 1.00 21.01 ? 203 ALA C C 1 ATOM 4174 O O . ALA B 1 145 ? 46.733 -96.534 29.216 1.00 21.75 ? 203 ALA C O 1 ATOM 4175 C CB . ALA B 1 145 ? 45.452 -99.305 28.356 1.00 25.50 ? 203 ALA C CB 1 ATOM 4176 N N . MET B 1 146 ? 48.383 -97.842 28.411 1.00 24.43 ? 204 MET C N 1 ATOM 4177 C CA . MET B 1 146 ? 49.126 -96.753 27.787 1.00 24.54 ? 204 MET C CA 1 ATOM 4178 C C . MET B 1 146 ? 48.857 -96.749 26.290 1.00 21.03 ? 204 MET C C 1 ATOM 4179 O O . MET B 1 146 ? 48.803 -97.808 25.666 1.00 29.33 ? 204 MET C O 1 ATOM 4180 C CB . MET B 1 146 ? 50.625 -96.895 28.047 1.00 32.35 ? 204 MET C CB 1 ATOM 4181 C CG . MET B 1 146 ? 51.023 -96.685 29.489 1.00 31.84 ? 204 MET C CG 1 ATOM 4182 S SD . MET B 1 146 ? 52.684 -97.306 29.833 1.00 52.92 ? 204 MET C SD 1 ATOM 4183 C CE . MET B 1 146 ? 53.665 -96.447 28.606 1.00 34.05 ? 204 MET C CE 1 ATOM 4184 N N . ASP B 1 147 ? 48.690 -95.563 25.714 1.00 30.79 ? 205 ASP C N 1 ATOM 4185 C CA . ASP B 1 147 ? 48.472 -95.451 24.277 1.00 30.83 ? 205 ASP C CA 1 ATOM 4186 C C . ASP B 1 147 ? 49.803 -95.574 23.530 1.00 35.75 ? 205 ASP C C 1 ATOM 4187 O O . ASP B 1 147 ? 50.832 -95.885 24.131 1.00 31.39 ? 205 ASP C O 1 ATOM 4188 C CB . ASP B 1 147 ? 47.756 -94.133 23.934 1.00 30.06 ? 205 ASP C CB 1 ATOM 4189 C CG . ASP B 1 147 ? 48.526 -92.894 24.364 1.00 40.24 ? 205 ASP C CG 1 ATOM 4190 O OD1 . ASP B 1 147 ? 49.766 -92.947 24.505 1.00 43.96 ? 205 ASP C OD1 1 ATOM 4191 O OD2 . ASP B 1 147 ? 47.873 -91.844 24.546 1.00 42.46 ? 205 ASP C OD2 1 ATOM 4192 N N . LYS B 1 148 ? 49.779 -95.333 22.223 1.00 35.47 ? 206 LYS C N 1 ATOM 4193 C CA . LYS B 1 148 ? 50.964 -95.518 21.390 1.00 45.05 ? 206 LYS C CA 1 ATOM 4194 C C . LYS B 1 148 ? 52.073 -94.512 21.693 1.00 33.17 ? 206 LYS C C 1 ATOM 4195 O O . LYS B 1 148 ? 53.228 -94.735 21.330 1.00 42.22 ? 206 LYS C O 1 ATOM 4196 C CB . LYS B 1 148 ? 50.586 -95.433 19.911 1.00 44.20 ? 206 LYS C CB 1 ATOM 4197 C CG . LYS B 1 148 ? 50.083 -96.746 19.333 1.00 66.29 ? 206 LYS C CG 1 ATOM 4198 C CD . LYS B 1 148 ? 49.556 -96.571 17.918 1.00 77.34 ? 206 LYS C CD 1 ATOM 4199 C CE . LYS B 1 148 ? 48.527 -97.635 17.562 1.00 77.54 ? 206 LYS C CE 1 ATOM 4200 N NZ . LYS B 1 148 ? 47.571 -97.146 16.532 1.00 84.77 ? 206 LYS C NZ 1 ATOM 4201 N N . ASN B 1 149 ? 51.721 -93.412 22.355 1.00 29.99 ? 207 ASN C N 1 ATOM 4202 C CA . ASN B 1 149 ? 52.699 -92.390 22.726 1.00 36.13 ? 207 ASN C CA 1 ATOM 4203 C C . ASN B 1 149 ? 53.115 -92.491 24.192 1.00 37.71 ? 207 ASN C C 1 ATOM 4204 O O . ASN B 1 149 ? 53.578 -91.515 24.782 1.00 38.18 ? 207 ASN C O 1 ATOM 4205 C CB . ASN B 1 149 ? 52.139 -90.996 22.442 1.00 37.68 ? 207 ASN C CB 1 ATOM 4206 C CG . ASN B 1 149 ? 51.825 -90.782 20.974 1.00 50.02 ? 207 ASN C CG 1 ATOM 4207 O OD1 . ASN B 1 149 ? 50.733 -90.341 20.618 1.00 53.88 ? 207 ASN C OD1 1 ATOM 4208 N ND2 . ASN B 1 149 ? 52.785 -91.100 20.111 1.00 44.22 ? 207 ASN C ND2 1 ATOM 4209 N N . ASN B 1 150 ? 52.941 -93.677 24.770 1.00 33.21 ? 208 ASN C N 1 ATOM 4210 C CA . ASN B 1 150 ? 53.324 -93.948 26.155 1.00 35.28 ? 208 ASN C CA 1 ATOM 4211 C C . ASN B 1 150 ? 52.603 -93.073 27.181 1.00 34.34 ? 208 ASN C C 1 ATOM 4212 O O . ASN B 1 150 ? 53.057 -92.944 28.319 1.00 42.83 ? 208 ASN C O 1 ATOM 4213 C CB . ASN B 1 150 ? 54.837 -93.784 26.328 1.00 38.76 ? 208 ASN C CB 1 ATOM 4214 C CG . ASN B 1 150 ? 55.630 -94.686 25.406 1.00 34.06 ? 208 ASN C CG 1 ATOM 4215 O OD1 . ASN B 1 150 ? 56.547 -94.240 24.716 1.00 41.22 ? 208 ASN C OD1 1 ATOM 4216 N ND2 . ASN B 1 150 ? 55.277 -95.965 25.387 1.00 35.87 ? 208 ASN C ND2 1 ATOM 4217 N N . LYS B 1 151 ? 51.480 -92.483 26.782 1.00 27.72 ? 209 LYS C N 1 ATOM 4218 C CA . LYS B 1 151 ? 50.662 -91.697 27.702 1.00 35.49 ? 209 LYS C CA 1 ATOM 4219 C C . LYS B 1 151 ? 49.573 -92.558 28.329 1.00 36.35 ? 209 LYS C C 1 ATOM 4220 O O . LYS B 1 151 ? 48.976 -93.402 27.662 1.00 34.66 ? 209 LYS C O 1 ATOM 4221 C CB . LYS B 1 151 ? 50.023 -90.508 26.986 1.00 42.84 ? 209 LYS C CB 1 ATOM 4222 C CG . LYS B 1 151 ? 51.018 -89.523 26.395 1.00 53.06 ? 209 LYS C CG 1 ATOM 4223 C CD . LYS B 1 151 ? 50.664 -88.088 26.760 1.00 65.25 ? 209 LYS C CD 1 ATOM 4224 C CE . LYS B 1 151 ? 51.143 -87.108 25.703 1.00 74.01 ? 209 LYS C CE 1 ATOM 4225 N NZ . LYS B 1 151 ? 50.975 -85.693 26.138 1.00 87.14 ? 209 LYS C NZ 1 ATOM 4226 N N . ALA B 1 152 ? 49.313 -92.332 29.612 1.00 34.76 ? 210 ALA C N 1 ATOM 4227 C CA . ALA B 1 152 ? 48.273 -93.065 30.321 1.00 34.34 ? 210 ALA C CA 1 ATOM 4228 C C . ALA B 1 152 ? 46.892 -92.731 29.764 1.00 36.17 ? 210 ALA C C 1 ATOM 4229 O O . ALA B 1 152 ? 46.578 -91.567 29.515 1.00 27.06 ? 210 ALA C O 1 ATOM 4230 C CB . ALA B 1 152 ? 48.331 -92.755 31.807 1.00 35.47 ? 210 ALA C CB 1 ATOM 4231 N N . THR B 1 153 ? 46.079 -93.763 29.563 1.00 28.90 ? 211 THR C N 1 ATOM 4232 C CA . THR B 1 153 ? 44.688 -93.588 29.159 1.00 26.93 ? 211 THR C CA 1 ATOM 4233 C C . THR B 1 153 ? 43.797 -93.736 30.385 1.00 24.62 ? 211 THR C C 1 ATOM 4234 O O . THR B 1 153 ? 44.290 -93.801 31.511 1.00 28.13 ? 211 THR C O 1 ATOM 4235 C CB . THR B 1 153 ? 44.262 -94.615 28.094 1.00 25.44 ? 211 THR C CB 1 ATOM 4236 O OG1 . THR B 1 153 ? 44.155 -95.914 28.692 1.00 20.47 ? 211 THR C OG1 1 ATOM 4237 C CG2 . THR B 1 153 ? 45.269 -94.657 26.952 1.00 25.26 ? 211 THR C CG2 1 ATOM 4238 N N . LYS B 1 154 ? 42.488 -93.794 30.159 1.00 31.16 ? 212 LYS C N 1 ATOM 4239 C CA . LYS B 1 154 ? 41.530 -94.047 31.230 1.00 27.84 ? 212 LYS C CA 1 ATOM 4240 C C . LYS B 1 154 ? 40.822 -95.385 31.010 1.00 29.71 ? 212 LYS C C 1 ATOM 4241 O O . LYS B 1 154 ? 39.759 -95.641 31.576 1.00 27.86 ? 212 LYS C O 1 ATOM 4242 C CB . LYS B 1 154 ? 40.524 -92.898 31.319 1.00 33.16 ? 212 LYS C CB 1 ATOM 4243 C CG . LYS B 1 154 ? 41.123 -91.629 31.911 1.00 40.01 ? 212 LYS C CG 1 ATOM 4244 C CD . LYS B 1 154 ? 40.204 -90.430 31.741 1.00 45.39 ? 212 LYS C CD 1 ATOM 4245 C CE . LYS B 1 154 ? 40.680 -89.244 32.572 1.00 66.59 ? 212 LYS C CE 1 ATOM 4246 N NZ . LYS B 1 154 ? 41.134 -88.101 31.732 1.00 69.50 ? 212 LYS C NZ 1 ATOM 4247 N N . TYR B 1 155 ? 41.433 -96.237 30.190 1.00 25.91 ? 213 TYR C N 1 ATOM 4248 C CA . TYR B 1 155 ? 40.924 -97.582 29.945 1.00 19.54 ? 213 TYR C CA 1 ATOM 4249 C C . TYR B 1 155 ? 41.509 -98.558 30.960 1.00 24.35 ? 213 TYR C C 1 ATOM 4250 O O . TYR B 1 155 ? 42.728 -98.714 31.051 1.00 21.20 ? 213 TYR C O 1 ATOM 4251 C CB . TYR B 1 155 ? 41.259 -98.029 28.521 1.00 17.31 ? 213 TYR C CB 1 ATOM 4252 C CG . TYR B 1 155 ? 40.770 -99.418 28.179 1.00 25.34 ? 213 TYR C CG 1 ATOM 4253 C CD1 . TYR B 1 155 ? 41.549 -100.534 28.450 1.00 25.64 ? 213 TYR C CD1 1 ATOM 4254 C CD2 . TYR B 1 155 ? 39.532 -99.613 27.582 1.00 24.38 ? 213 TYR C CD2 1 ATOM 4255 C CE1 . TYR B 1 155 ? 41.110 -101.806 28.140 1.00 32.08 ? 213 TYR C CE1 1 ATOM 4256 C CE2 . TYR B 1 155 ? 39.083 -100.885 27.266 1.00 21.52 ? 213 TYR C CE2 1 ATOM 4257 C CZ . TYR B 1 155 ? 39.877 -101.977 27.547 1.00 31.18 ? 213 TYR C CZ 1 ATOM 4258 O OH . TYR B 1 155 ? 39.445 -103.247 27.238 1.00 33.40 ? 213 TYR C OH 1 ATOM 4259 N N . ARG B 1 156 ? 40.631 -99.211 31.717 1.00 15.90 ? 214 ARG C N 1 ATOM 4260 C CA . ARG B 1 156 ? 41.041 -100.123 32.780 1.00 19.93 ? 214 ARG C CA 1 ATOM 4261 C C . ARG B 1 156 ? 40.481 -101.523 32.566 1.00 28.77 ? 214 ARG C C 1 ATOM 4262 O O . ARG B 1 156 ? 39.428 -101.696 31.951 1.00 26.77 ? 214 ARG C O 1 ATOM 4263 C CB . ARG B 1 156 ? 40.589 -99.590 34.135 1.00 19.66 ? 214 ARG C CB 1 ATOM 4264 C CG . ARG B 1 156 ? 41.165 -98.230 34.483 1.00 16.94 ? 214 ARG C CG 1 ATOM 4265 C CD . ARG B 1 156 ? 40.682 -97.770 35.841 1.00 21.16 ? 214 ARG C CD 1 ATOM 4266 N NE . ARG B 1 156 ? 41.366 -96.563 36.294 1.00 27.45 ? 214 ARG C NE 1 ATOM 4267 C CZ . ARG B 1 156 ? 41.075 -95.333 35.882 1.00 25.50 ? 214 ARG C CZ 1 ATOM 4268 N NH1 . ARG B 1 156 ? 40.112 -95.129 34.992 1.00 24.07 ? 214 ARG C NH1 1 ATOM 4269 N NH2 . ARG B 1 156 ? 41.754 -94.300 36.360 1.00 27.47 ? 214 ARG C NH2 1 ATOM 4270 N N . TYR B 1 157 ? 41.188 -102.514 33.097 1.00 25.77 ? 215 TYR C N 1 ATOM 4271 C CA . TYR B 1 157 ? 40.843 -103.914 32.893 1.00 21.53 ? 215 TYR C CA 1 ATOM 4272 C C . TYR B 1 157 ? 40.134 -104.512 34.103 1.00 25.64 ? 215 TYR C C 1 ATOM 4273 O O . TYR B 1 157 ? 40.393 -104.109 35.236 1.00 22.75 ? 215 TYR C O 1 ATOM 4274 C CB . TYR B 1 157 ? 42.101 -104.721 32.587 1.00 19.66 ? 215 TYR C CB 1 ATOM 4275 C CG . TYR B 1 157 ? 42.777 -104.305 31.304 1.00 31.11 ? 215 TYR C CG 1 ATOM 4276 C CD1 . TYR B 1 157 ? 43.651 -103.228 31.280 1.00 30.38 ? 215 TYR C CD1 1 ATOM 4277 C CD2 . TYR B 1 157 ? 42.535 -104.981 30.116 1.00 27.31 ? 215 TYR C CD2 1 ATOM 4278 C CE1 . TYR B 1 157 ? 44.269 -102.838 30.112 1.00 33.46 ? 215 TYR C CE1 1 ATOM 4279 C CE2 . TYR B 1 157 ? 43.151 -104.598 28.940 1.00 32.45 ? 215 TYR C CE2 1 ATOM 4280 C CZ . TYR B 1 157 ? 44.017 -103.525 28.946 1.00 32.56 ? 215 TYR C CZ 1 ATOM 4281 O OH . TYR B 1 157 ? 44.632 -103.135 27.781 1.00 35.59 ? 215 TYR C OH 1 ATOM 4282 N N . PRO B 1 158 ? 39.242 -105.490 33.869 1.00 20.48 ? 216 PRO C N 1 ATOM 4283 C CA . PRO B 1 158 ? 38.559 -106.133 34.996 1.00 19.19 ? 216 PRO C CA 1 ATOM 4284 C C . PRO B 1 158 ? 39.507 -107.003 35.810 1.00 19.47 ? 216 PRO C C 1 ATOM 4285 O O . PRO B 1 158 ? 40.592 -107.341 35.338 1.00 18.38 ? 216 PRO C O 1 ATOM 4286 C CB . PRO B 1 158 ? 37.481 -106.981 34.317 1.00 23.00 ? 216 PRO C CB 1 ATOM 4287 C CG . PRO B 1 158 ? 38.042 -107.287 32.974 1.00 17.00 ? 216 PRO C CG 1 ATOM 4288 C CD . PRO B 1 158 ? 38.839 -106.073 32.577 1.00 21.01 ? 216 PRO C CD 1 ATOM 4289 N N . PHE B 1 159 ? 39.093 -107.355 37.021 1.00 20.42 ? 217 PHE C N 1 ATOM 4290 C CA . PHE B 1 159 ? 39.904 -108.176 37.900 1.00 22.86 ? 217 PHE C CA 1 ATOM 4291 C C . PHE B 1 159 ? 39.127 -109.373 38.418 1.00 17.36 ? 217 PHE C C 1 ATOM 4292 O O . PHE B 1 159 ? 37.889 -109.367 38.461 1.00 19.80 ? 217 PHE C O 1 ATOM 4293 C CB . PHE B 1 159 ? 40.413 -107.353 39.086 1.00 17.99 ? 217 PHE C CB 1 ATOM 4294 C CG . PHE B 1 159 ? 39.355 -107.053 40.106 1.00 18.36 ? 217 PHE C CG 1 ATOM 4295 C CD1 . PHE B 1 159 ? 39.124 -107.920 41.162 1.00 21.20 ? 217 PHE C CD1 1 ATOM 4296 C CD2 . PHE B 1 159 ? 38.584 -105.910 40.006 1.00 22.83 ? 217 PHE C CD2 1 ATOM 4297 C CE1 . PHE B 1 159 ? 38.144 -107.650 42.097 1.00 25.11 ? 217 PHE C CE1 1 ATOM 4298 C CE2 . PHE B 1 159 ? 37.606 -105.634 40.940 1.00 21.97 ? 217 PHE C CE2 1 ATOM 4299 C CZ . PHE B 1 159 ? 37.386 -106.504 41.986 1.00 22.71 ? 217 PHE C CZ 1 ATOM 4300 N N . VAL B 1 160 ? 39.880 -110.390 38.822 1.00 12.46 ? 218 VAL C N 1 ATOM 4301 C CA . VAL B 1 160 ? 39.335 -111.523 39.551 1.00 16.23 ? 218 VAL C CA 1 ATOM 4302 C C . VAL B 1 160 ? 40.151 -111.714 40.818 1.00 22.42 ? 218 VAL C C 1 ATOM 4303 O O . VAL B 1 160 ? 41.364 -111.918 40.745 1.00 18.83 ? 218 VAL C O 1 ATOM 4304 C CB . VAL B 1 160 ? 39.364 -112.823 38.726 1.00 17.37 ? 218 VAL C CB 1 ATOM 4305 C CG1 . VAL B 1 160 ? 38.945 -114.020 39.587 1.00 18.14 ? 218 VAL C CG1 1 ATOM 4306 C CG2 . VAL B 1 160 ? 38.457 -112.700 37.519 1.00 19.12 ? 218 VAL C CG2 1 ATOM 4307 N N . TYR B 1 161 ? 39.500 -111.645 41.974 1.00 18.99 ? 219 TYR C N 1 ATOM 4308 C CA . TYR B 1 161 ? 40.185 -111.960 43.221 1.00 17.70 ? 219 TYR C CA 1 ATOM 4309 C C . TYR B 1 161 ? 39.933 -113.411 43.605 1.00 17.56 ? 219 TYR C C 1 ATOM 4310 O O . TYR B 1 161 ? 38.785 -113.851 43.721 1.00 22.96 ? 219 TYR C O 1 ATOM 4311 C CB . TYR B 1 161 ? 39.750 -111.034 44.360 1.00 17.88 ? 219 TYR C CB 1 ATOM 4312 C CG . TYR B 1 161 ? 40.539 -111.276 45.636 1.00 16.93 ? 219 TYR C CG 1 ATOM 4313 C CD1 . TYR B 1 161 ? 41.929 -111.268 45.623 1.00 22.14 ? 219 TYR C CD1 1 ATOM 4314 C CD2 . TYR B 1 161 ? 39.900 -111.519 46.845 1.00 17.41 ? 219 TYR C CD2 1 ATOM 4315 C CE1 . TYR B 1 161 ? 42.659 -111.494 46.771 1.00 23.57 ? 219 TYR C CE1 1 ATOM 4316 C CE2 . TYR B 1 161 ? 40.627 -111.744 48.007 1.00 23.45 ? 219 TYR C CE2 1 ATOM 4317 C CZ . TYR B 1 161 ? 42.007 -111.731 47.961 1.00 23.68 ? 219 TYR C CZ 1 ATOM 4318 O OH . TYR B 1 161 ? 42.745 -111.953 49.102 1.00 29.32 ? 219 TYR C OH 1 ATOM 4319 N N . ASP B 1 162 ? 41.029 -114.146 43.768 1.00 18.47 ? 220 ASP C N 1 ATOM 4320 C CA . ASP B 1 162 ? 41.009 -115.508 44.286 1.00 15.96 ? 220 ASP C CA 1 ATOM 4321 C C . ASP B 1 162 ? 41.300 -115.447 45.783 1.00 23.35 ? 220 ASP C C 1 ATOM 4322 O O . ASP B 1 162 ? 42.456 -115.312 46.201 1.00 20.53 ? 220 ASP C O 1 ATOM 4323 C CB . ASP B 1 162 ? 42.035 -116.378 43.551 1.00 15.99 ? 220 ASP C CB 1 ATOM 4324 C CG . ASP B 1 162 ? 41.997 -117.839 43.981 1.00 18.09 ? 220 ASP C CG 1 ATOM 4325 O OD1 . ASP B 1 162 ? 41.538 -118.137 45.103 1.00 28.15 ? 220 ASP C OD1 1 ATOM 4326 O OD2 . ASP B 1 162 ? 42.448 -118.696 43.191 1.00 32.31 ? 220 ASP C OD2 1 ATOM 4327 N N . SER B 1 163 ? 40.236 -115.548 46.577 1.00 20.62 ? 221 SER C N 1 ATOM 4328 C CA . SER B 1 163 ? 40.308 -115.340 48.019 1.00 27.16 ? 221 SER C CA 1 ATOM 4329 C C . SER B 1 163 ? 40.897 -116.537 48.757 1.00 24.76 ? 221 SER C C 1 ATOM 4330 O O . SER B 1 163 ? 41.371 -116.401 49.883 1.00 33.82 ? 221 SER C O 1 ATOM 4331 C CB . SER B 1 163 ? 38.916 -115.028 48.572 1.00 29.30 ? 221 SER C CB 1 ATOM 4332 O OG . SER B 1 163 ? 38.027 -116.111 48.357 1.00 30.66 ? 221 SER C OG 1 ATOM 4333 N N . LYS B 1 164 ? 40.824 -117.712 48.153 1.00 29.37 ? 222 LYS C N 1 ATOM 4334 C CA . LYS B 1 164 ? 41.417 -118.904 48.731 1.00 29.30 ? 222 LYS C CA 1 ATOM 4335 C C . LYS B 1 164 ? 42.940 -118.887 48.636 1.00 31.94 ? 222 LYS C C 1 ATOM 4336 O O . LYS B 1 164 ? 43.636 -119.096 49.602 1.00 34.18 ? 222 LYS C O 1 ATOM 4337 C CB . LYS B 1 164 ? 40.866 -120.166 48.081 1.00 29.97 ? 222 LYS C CB 1 ATOM 4338 C CG . LYS B 1 164 ? 41.443 -121.427 48.680 1.00 53.08 ? 222 LYS C CG 1 ATOM 4339 C CD . LYS B 1 164 ? 40.926 -122.701 48.038 1.00 69.65 ? 222 LYS C CD 1 ATOM 4340 C CE . LYS B 1 164 ? 41.258 -123.903 48.907 1.00 82.29 ? 222 LYS C CE 1 ATOM 4341 N NZ . LYS B 1 164 ? 40.773 -125.185 48.331 1.00 106.12 ? 222 LYS C NZ 1 ATOM 4342 N N . LYS B 1 165 ? 43.445 -118.589 47.455 1.00 27.24 ? 223 LYS C N 1 ATOM 4343 C CA . LYS B 1 165 ? 44.882 -118.496 47.228 1.00 36.31 ? 223 LYS C CA 1 ATOM 4344 C C . LYS B 1 165 ? 45.407 -117.102 47.565 1.00 26.31 ? 223 LYS C C 1 ATOM 4345 O O . LYS B 1 165 ? 46.617 -116.880 47.601 1.00 22.56 ? 223 LYS C O 1 ATOM 4346 C CB . LYS B 1 165 ? 45.212 -118.843 45.777 1.00 33.10 ? 223 LYS C CB 1 ATOM 4347 C CG . LYS B 1 165 ? 44.987 -120.305 45.430 1.00 38.03 ? 223 LYS C CG 1 ATOM 4348 C CD . LYS B 1 165 ? 45.188 -120.550 43.944 1.00 38.65 ? 223 LYS C CD 1 ATOM 4349 C CE . LYS B 1 165 ? 45.999 -121.809 43.689 1.00 56.22 ? 223 LYS C CE 1 ATOM 4350 N NZ . LYS B 1 165 ? 46.252 -122.025 42.238 1.00 55.58 ? 223 LYS C NZ 1 ATOM 4351 N N . ARG B 1 166 ? 44.487 -116.175 47.821 1.00 22.69 ? 224 ARG C N 1 ATOM 4352 C CA . ARG B 1 166 ? 44.827 -114.782 48.097 1.00 20.14 ? 224 ARG C CA 1 ATOM 4353 C C . ARG B 1 166 ? 45.643 -114.211 46.947 1.00 33.79 ? 224 ARG C C 1 ATOM 4354 O O . ARG B 1 166 ? 46.741 -113.681 47.145 1.00 21.21 ? 224 ARG C O 1 ATOM 4355 C CB . ARG B 1 166 ? 45.586 -114.657 49.422 1.00 25.06 ? 224 ARG C CB 1 ATOM 4356 C CG . ARG B 1 166 ? 44.814 -115.219 50.606 1.00 26.79 ? 224 ARG C CG 1 ATOM 4357 C CD . ARG B 1 166 ? 45.513 -114.957 51.926 1.00 30.25 ? 224 ARG C CD 1 ATOM 4358 N NE . ARG B 1 166 ? 45.252 -113.605 52.423 1.00 35.66 ? 224 ARG C NE 1 ATOM 4359 C CZ . ARG B 1 166 ? 46.181 -112.708 52.748 1.00 40.31 ? 224 ARG C CZ 1 ATOM 4360 N NH1 . ARG B 1 166 ? 47.476 -112.984 52.642 1.00 42.23 ? 224 ARG C NH1 1 ATOM 4361 N NH2 . ARG B 1 166 ? 45.809 -111.515 53.189 1.00 37.06 ? 224 ARG C NH2 1 ATOM 4362 N N . LEU B 1 167 ? 45.089 -114.329 45.742 1.00 25.05 ? 225 LEU C N 1 ATOM 4363 C CA . LEU B 1 167 ? 45.752 -113.838 44.539 1.00 18.28 ? 225 LEU C CA 1 ATOM 4364 C C . LEU B 1 167 ? 44.839 -112.898 43.768 1.00 21.60 ? 225 LEU C C 1 ATOM 4365 O O . LEU B 1 167 ? 43.668 -113.201 43.540 1.00 26.86 ? 225 LEU C O 1 ATOM 4366 C CB . LEU B 1 167 ? 46.184 -114.996 43.635 1.00 22.64 ? 225 LEU C CB 1 ATOM 4367 C CG . LEU B 1 167 ? 47.339 -115.879 44.109 1.00 29.22 ? 225 LEU C CG 1 ATOM 4368 C CD1 . LEU B 1 167 ? 47.528 -117.047 43.151 1.00 32.33 ? 225 LEU C CD1 1 ATOM 4369 C CD2 . LEU B 1 167 ? 48.627 -115.082 44.228 1.00 27.61 ? 225 LEU C CD2 1 ATOM 4370 N N . CYS B 1 168 ? 45.388 -111.755 43.373 1.00 18.43 ? 226 CYS C N 1 ATOM 4371 C CA . CYS B 1 168 ? 44.655 -110.778 42.585 1.00 18.54 ? 226 CYS C CA 1 ATOM 4372 C C . CYS B 1 168 ? 45.016 -110.918 41.110 1.00 23.84 ? 226 CYS C C 1 ATOM 4373 O O . CYS B 1 168 ? 46.185 -110.805 40.735 1.00 29.90 ? 226 CYS C O 1 ATOM 4374 C CB . CYS B 1 168 ? 44.950 -109.357 43.070 1.00 22.89 ? 226 CYS C CB 1 ATOM 4375 S SG . CYS B 1 168 ? 43.951 -108.096 42.243 1.00 41.70 ? 226 CYS C SG 1 ATOM 4376 N N . HIS B 1 169 ? 44.009 -111.115 40.288 1.00 22.19 ? 227 HIS C N 1 ATOM 4377 C CA . HIS B 1 169 ? 44.220 -111.265 38.872 1.00 18.99 ? 227 HIS C CA 1 ATOM 4378 C C . HIS B 1 169 ? 43.660 -110.125 38.053 1.00 20.08 ? 227 HIS C C 1 ATOM 4379 O O . HIS B 1 169 ? 42.527 -109.720 38.236 1.00 22.62 ? 227 HIS C O 1 ATOM 4380 C CB . HIS B 1 169 ? 43.499 -112.517 38.364 1.00 20.53 ? 227 HIS C CB 1 ATOM 4381 C CG . HIS B 1 169 ? 44.069 -113.808 38.842 1.00 15.09 ? 227 HIS C CG 1 ATOM 4382 N ND1 . HIS B 1 169 ? 43.694 -114.390 40.029 1.00 21.85 ? 227 HIS C ND1 1 ATOM 4383 C CD2 . HIS B 1 169 ? 44.937 -114.665 38.264 1.00 20.24 ? 227 HIS C CD2 1 ATOM 4384 C CE1 . HIS B 1 169 ? 44.328 -115.534 40.176 1.00 22.57 ? 227 HIS C CE1 1 ATOM 4385 N NE2 . HIS B 1 169 ? 45.089 -115.725 39.118 1.00 20.80 ? 227 HIS C NE2 1 ATOM 4386 N N . ILE B 1 170 ? 44.464 -109.619 37.139 1.00 13.77 ? 228 ILE C N 1 ATOM 4387 C CA . ILE B 1 170 ? 44.001 -108.647 36.155 1.00 17.28 ? 228 ILE C CA 1 ATOM 4388 C C . ILE B 1 170 ? 43.797 -109.382 34.833 1.00 14.03 ? 228 ILE C C 1 ATOM 4389 O O . ILE B 1 170 ? 44.677 -110.122 34.394 1.00 18.24 ? 228 ILE C O 1 ATOM 4390 C CB . ILE B 1 170 ? 44.998 -107.493 35.947 1.00 18.30 ? 228 ILE C CB 1 ATOM 4391 C CG1 . ILE B 1 170 ? 45.375 -106.839 37.283 1.00 22.02 ? 228 ILE C CG1 1 ATOM 4392 C CG2 . ILE B 1 170 ? 44.419 -106.466 34.977 1.00 19.46 ? 228 ILE C CG2 1 ATOM 4393 C CD1 . ILE B 1 170 ? 44.256 -106.087 37.953 1.00 28.69 ? 228 ILE C CD1 1 ATOM 4394 N N . LEU B 1 171 ? 42.645 -109.179 34.202 1.00 19.69 ? 229 LEU C N 1 ATOM 4395 C CA . LEU B 1 171 ? 42.335 -109.860 32.948 1.00 18.70 ? 229 LEU C CA 1 ATOM 4396 C C . LEU B 1 171 ? 42.619 -108.961 31.756 1.00 17.97 ? 229 LEU C C 1 ATOM 4397 O O . LEU B 1 171 ? 42.078 -107.863 31.653 1.00 25.29 ? 229 LEU C O 1 ATOM 4398 C CB . LEU B 1 171 ? 40.872 -110.305 32.923 1.00 15.86 ? 229 LEU C CB 1 ATOM 4399 C CG . LEU B 1 171 ? 40.406 -111.201 34.073 1.00 23.32 ? 229 LEU C CG 1 ATOM 4400 C CD1 . LEU B 1 171 ? 38.960 -111.609 33.856 1.00 20.86 ? 229 LEU C CD1 1 ATOM 4401 C CD2 . LEU B 1 171 ? 41.290 -112.428 34.214 1.00 16.63 ? 229 LEU C CD2 1 ATOM 4402 N N . TYR B 1 172 ? 43.469 -109.434 30.852 1.00 15.80 ? 230 TYR C N 1 ATOM 4403 C CA . TYR B 1 172 ? 43.760 -108.702 29.628 1.00 16.87 ? 230 TYR C CA 1 ATOM 4404 C C . TYR B 1 172 ? 42.539 -108.715 28.709 1.00 21.58 ? 230 TYR C C 1 ATOM 4405 O O . TYR B 1 172 ? 42.310 -107.774 27.950 1.00 27.28 ? 230 TYR C O 1 ATOM 4406 C CB . TYR B 1 172 ? 44.978 -109.306 28.922 1.00 17.69 ? 230 TYR C CB 1 ATOM 4407 C CG . TYR B 1 172 ? 45.486 -108.495 27.751 1.00 26.43 ? 230 TYR C CG 1 ATOM 4408 C CD1 . TYR B 1 172 ? 45.762 -107.141 27.887 1.00 33.16 ? 230 TYR C CD1 1 ATOM 4409 C CD2 . TYR B 1 172 ? 45.709 -109.087 26.516 1.00 29.40 ? 230 TYR C CD2 1 ATOM 4410 C CE1 . TYR B 1 172 ? 46.232 -106.396 26.823 1.00 36.77 ? 230 TYR C CE1 1 ATOM 4411 C CE2 . TYR B 1 172 ? 46.181 -108.350 25.445 1.00 43.18 ? 230 TYR C CE2 1 ATOM 4412 C CZ . TYR B 1 172 ? 46.442 -107.006 25.604 1.00 49.48 ? 230 TYR C CZ 1 ATOM 4413 O OH . TYR B 1 172 ? 46.911 -106.267 24.541 1.00 58.04 ? 230 TYR C OH 1 ATOM 4414 N N . VAL B 1 173 ? 41.754 -109.787 28.795 1.00 19.03 ? 231 VAL C N 1 ATOM 4415 C CA . VAL B 1 173 ? 40.539 -109.928 27.994 1.00 16.96 ? 231 VAL C CA 1 ATOM 4416 C C . VAL B 1 173 ? 39.325 -109.454 28.786 1.00 17.70 ? 231 VAL C C 1 ATOM 4417 O O . VAL B 1 173 ? 39.021 -109.989 29.854 1.00 26.18 ? 231 VAL C O 1 ATOM 4418 C CB . VAL B 1 173 ? 40.329 -111.392 27.544 1.00 21.43 ? 231 VAL C CB 1 ATOM 4419 C CG1 . VAL B 1 173 ? 39.020 -111.552 26.761 1.00 20.61 ? 231 VAL C CG1 1 ATOM 4420 C CG2 . VAL B 1 173 ? 41.511 -111.857 26.702 1.00 16.19 ? 231 VAL C CG2 1 ATOM 4421 N N . SER B 1 174 ? 38.637 -108.450 28.250 1.00 16.78 ? 232 SER C N 1 ATOM 4422 C CA . SER B 1 174 ? 37.459 -107.878 28.894 1.00 22.17 ? 232 SER C CA 1 ATOM 4423 C C . SER B 1 174 ? 36.163 -108.458 28.328 1.00 20.12 ? 232 SER C C 1 ATOM 4424 O O . SER B 1 174 ? 35.080 -108.175 28.840 1.00 18.91 ? 232 SER C O 1 ATOM 4425 C CB . SER B 1 174 ? 37.454 -106.356 28.739 1.00 23.39 ? 232 SER C CB 1 ATOM 4426 O OG . SER B 1 174 ? 38.630 -105.786 29.283 1.00 36.35 ? 232 SER C OG 1 ATOM 4427 N N . MET B 1 175 ? 36.270 -109.254 27.268 1.00 21.13 ? 233 MET C N 1 ATOM 4428 C CA . MET B 1 175 ? 35.114 -109.984 26.757 1.00 21.70 ? 233 MET C CA 1 ATOM 4429 C C . MET B 1 175 ? 34.658 -110.975 27.819 1.00 18.58 ? 233 MET C C 1 ATOM 4430 O O . MET B 1 175 ? 35.472 -111.486 28.587 1.00 19.40 ? 233 MET C O 1 ATOM 4431 C CB . MET B 1 175 ? 35.444 -110.718 25.456 1.00 16.44 ? 233 MET C CB 1 ATOM 4432 C CG . MET B 1 175 ? 35.760 -109.807 24.275 1.00 22.99 ? 233 MET C CG 1 ATOM 4433 S SD . MET B 1 175 ? 35.901 -110.706 22.715 1.00 26.09 ? 233 MET C SD 1 ATOM 4434 C CE . MET B 1 175 ? 37.301 -111.770 23.060 1.00 24.50 ? 233 MET C CE 1 ATOM 4435 N N . GLN B 1 176 ? 33.357 -111.238 27.862 1.00 16.24 ? 234 GLN C N 1 ATOM 4436 C CA . GLN B 1 176 ? 32.791 -112.142 28.857 1.00 18.10 ? 234 GLN C CA 1 ATOM 4437 C C . GLN B 1 176 ? 31.907 -113.208 28.221 1.00 13.71 ? 234 GLN C C 1 ATOM 4438 O O . GLN B 1 176 ? 31.627 -114.234 28.839 1.00 16.54 ? 234 GLN C O 1 ATOM 4439 C CB . GLN B 1 176 ? 32.000 -111.342 29.891 1.00 16.20 ? 234 GLN C CB 1 ATOM 4440 C CG . GLN B 1 176 ? 32.881 -110.478 30.784 1.00 16.90 ? 234 GLN C CG 1 ATOM 4441 C CD . GLN B 1 176 ? 32.213 -109.185 31.179 1.00 15.43 ? 234 GLN C CD 1 ATOM 4442 O OE1 . GLN B 1 176 ? 31.321 -109.168 32.027 1.00 20.51 ? 234 GLN C OE1 1 ATOM 4443 N NE2 . GLN B 1 176 ? 32.632 -108.089 30.558 1.00 18.94 ? 234 GLN C NE2 1 ATOM 4444 N N . LEU B 1 177 ? 31.484 -112.971 26.982 1.00 21.81 ? 235 LEU C N 1 ATOM 4445 C CA . LEU B 1 177 ? 30.616 -113.907 26.281 1.00 16.52 ? 235 LEU C CA 1 ATOM 4446 C C . LEU B 1 177 ? 30.864 -113.896 24.778 1.00 16.48 ? 235 LEU C C 1 ATOM 4447 O O . LEU B 1 177 ? 30.845 -112.844 24.139 1.00 16.54 ? 235 LEU C O 1 ATOM 4448 C CB . LEU B 1 177 ? 29.150 -113.576 26.571 1.00 18.13 ? 235 LEU C CB 1 ATOM 4449 C CG . LEU B 1 177 ? 28.074 -114.384 25.838 1.00 35.99 ? 235 LEU C CG 1 ATOM 4450 C CD1 . LEU B 1 177 ? 28.160 -115.860 26.173 1.00 31.06 ? 235 LEU C CD1 1 ATOM 4451 C CD2 . LEU B 1 177 ? 26.703 -113.845 26.192 1.00 42.51 ? 235 LEU C CD2 1 ATOM 4452 N N . MET B 1 178 ? 31.107 -115.079 24.224 1.00 16.05 ? 236 MET C N 1 ATOM 4453 C CA . MET B 1 178 ? 31.134 -115.255 22.779 1.00 20.71 ? 236 MET C CA 1 ATOM 4454 C C . MET B 1 178 ? 30.520 -116.605 22.433 1.00 17.72 ? 236 MET C C 1 ATOM 4455 O O . MET B 1 178 ? 30.892 -117.633 23.002 1.00 15.68 ? 236 MET C O 1 ATOM 4456 C CB . MET B 1 178 ? 32.558 -115.156 22.226 1.00 19.68 ? 236 MET C CB 1 ATOM 4457 C CG . MET B 1 178 ? 32.598 -114.734 20.758 1.00 29.94 ? 236 MET C CG 1 ATOM 4458 S SD . MET B 1 178 ? 34.236 -114.839 20.014 1.00 48.78 ? 236 MET C SD 1 ATOM 4459 C CE . MET B 1 178 ? 35.144 -113.664 21.014 1.00 40.92 ? 236 MET C CE 1 ATOM 4460 N N . GLU B 1 179 ? 29.569 -116.584 21.504 1.00 19.43 ? 237 GLU C N 1 ATOM 4461 C CA . GLU B 1 179 ? 28.849 -117.785 21.097 1.00 28.28 ? 237 GLU C CA 1 ATOM 4462 C C . GLU B 1 179 ? 28.480 -117.712 19.616 1.00 23.57 ? 237 GLU C C 1 ATOM 4463 O O . GLU B 1 179 ? 28.343 -116.622 19.058 1.00 25.55 ? 237 GLU C O 1 ATOM 4464 C CB . GLU B 1 179 ? 27.589 -117.961 21.947 1.00 22.14 ? 237 GLU C CB 1 ATOM 4465 C CG . GLU B 1 179 ? 26.546 -116.874 21.734 1.00 30.31 ? 237 GLU C CG 1 ATOM 4466 C CD . GLU B 1 179 ? 25.448 -116.903 22.782 1.00 67.77 ? 237 GLU C CD 1 ATOM 4467 O OE1 . GLU B 1 179 ? 24.777 -115.866 22.972 1.00 48.34 ? 237 GLU C OE1 1 ATOM 4468 O OE2 . GLU B 1 179 ? 25.255 -117.964 23.414 1.00 53.93 ? 237 GLU C OE2 1 ATOM 4469 N N . GLY B 1 180 ? 28.324 -118.876 18.991 1.00 27.83 ? 238 GLY C N 1 ATOM 4470 C CA . GLY B 1 180 ? 27.948 -118.958 17.590 1.00 33.96 ? 238 GLY C CA 1 ATOM 4471 C C . GLY B 1 180 ? 29.094 -119.440 16.723 1.00 33.12 ? 238 GLY C C 1 ATOM 4472 O O . GLY B 1 180 ? 30.200 -118.900 16.783 1.00 27.60 ? 238 GLY C O 1 ATOM 4473 N N . LYS B 1 181 ? 28.824 -120.457 15.908 1.00 26.58 ? 239 LYS C N 1 ATOM 4474 C CA . LYS B 1 181 ? 29.846 -121.052 15.053 1.00 27.14 ? 239 LYS C CA 1 ATOM 4475 C C . LYS B 1 181 ? 30.357 -120.053 14.022 1.00 24.49 ? 239 LYS C C 1 ATOM 4476 O O . LYS B 1 181 ? 31.378 -120.277 13.379 1.00 31.09 ? 239 LYS C O 1 ATOM 4477 C CB . LYS B 1 181 ? 29.301 -122.298 14.348 1.00 39.17 ? 239 LYS C CB 1 ATOM 4478 C CG . LYS B 1 181 ? 28.256 -122.014 13.277 1.00 34.24 ? 239 LYS C CG 1 ATOM 4479 C CD . LYS B 1 181 ? 27.805 -123.297 12.597 0.82 48.58 ? 239 LYS C CD 1 ATOM 4480 C CE . LYS B 1 181 ? 26.713 -123.030 11.574 0.98 46.98 ? 239 LYS C CE 1 ATOM 4481 N NZ . LYS B 1 181 ? 25.464 -122.533 12.214 0.76 64.72 ? 239 LYS C NZ 1 ATOM 4482 N N . LYS B 1 182 ? 29.634 -118.953 13.860 1.00 26.18 ? 240 LYS C N 1 ATOM 4483 C CA . LYS B 1 182 ? 30.066 -117.880 12.979 1.00 30.91 ? 240 LYS C CA 1 ATOM 4484 C C . LYS B 1 182 ? 31.234 -117.105 13.596 1.00 29.52 ? 240 LYS C C 1 ATOM 4485 O O . LYS B 1 182 ? 32.001 -116.459 12.882 1.00 27.22 ? 240 LYS C O 1 ATOM 4486 C CB . LYS B 1 182 ? 28.888 -116.947 12.692 1.00 33.14 ? 240 LYS C CB 1 ATOM 4487 C CG . LYS B 1 182 ? 29.157 -115.854 11.674 1.00 40.68 ? 240 LYS C CG 1 ATOM 4488 C CD . LYS B 1 182 ? 27.843 -115.290 11.141 1.00 51.66 ? 240 LYS C CD 1 ATOM 4489 C CE . LYS B 1 182 ? 27.785 -113.772 11.217 1.00 71.37 ? 240 LYS C CE 1 ATOM 4490 N NZ . LYS B 1 182 ? 28.602 -113.113 10.162 1.00 61.99 ? 240 LYS C NZ 1 ATOM 4491 N N . TYR B 1 183 ? 31.372 -117.194 14.918 1.00 27.14 ? 241 TYR C N 1 ATOM 4492 C CA . TYR B 1 183 ? 32.327 -116.368 15.655 1.00 24.41 ? 241 TYR C CA 1 ATOM 4493 C C . TYR B 1 183 ? 33.395 -117.168 16.397 1.00 26.32 ? 241 TYR C C 1 ATOM 4494 O O . TYR B 1 183 ? 34.520 -116.696 16.567 1.00 25.68 ? 241 TYR C O 1 ATOM 4495 C CB . TYR B 1 183 ? 31.580 -115.486 16.658 1.00 22.66 ? 241 TYR C CB 1 ATOM 4496 C CG . TYR B 1 183 ? 30.553 -114.580 16.020 1.00 32.61 ? 241 TYR C CG 1 ATOM 4497 C CD1 . TYR B 1 183 ? 30.935 -113.590 15.126 1.00 34.90 ? 241 TYR C CD1 1 ATOM 4498 C CD2 . TYR B 1 183 ? 29.202 -114.709 16.316 1.00 34.47 ? 241 TYR C CD2 1 ATOM 4499 C CE1 . TYR B 1 183 ? 30.000 -112.756 14.539 1.00 37.24 ? 241 TYR C CE1 1 ATOM 4500 C CE2 . TYR B 1 183 ? 28.260 -113.879 15.735 1.00 34.81 ? 241 TYR C CE2 1 ATOM 4501 C CZ . TYR B 1 183 ? 28.666 -112.905 14.848 1.00 40.69 ? 241 TYR C CZ 1 ATOM 4502 O OH . TYR B 1 183 ? 27.736 -112.075 14.265 1.00 50.28 ? 241 TYR C OH 1 ATOM 4503 N N . CYS B 1 184 ? 33.046 -118.368 16.848 1.00 21.79 ? 242 CYS C N 1 ATOM 4504 C CA . CYS B 1 184 ? 33.950 -119.143 17.689 1.00 17.07 ? 242 CYS C CA 1 ATOM 4505 C C . CYS B 1 184 ? 33.661 -120.636 17.632 1.00 19.25 ? 242 CYS C C 1 ATOM 4506 O O . CYS B 1 184 ? 32.585 -121.056 17.210 1.00 26.85 ? 242 CYS C O 1 ATOM 4507 C CB . CYS B 1 184 ? 33.860 -118.652 19.136 1.00 23.25 ? 242 CYS C CB 1 ATOM 4508 S SG . CYS B 1 184 ? 32.177 -118.651 19.801 1.00 24.75 ? 242 CYS C SG 1 ATOM 4509 N N . SER B 1 185 ? 34.634 -121.428 18.074 1.00 19.86 ? 243 SER C N 1 ATOM 4510 C CA . SER B 1 185 ? 34.551 -122.881 18.014 1.00 16.37 ? 243 SER C CA 1 ATOM 4511 C C . SER B 1 185 ? 34.266 -123.513 19.374 1.00 23.98 ? 243 SER C C 1 ATOM 4512 O O . SER B 1 185 ? 34.568 -122.935 20.421 1.00 21.88 ? 243 SER C O 1 ATOM 4513 C CB . SER B 1 185 ? 35.852 -123.452 17.456 1.00 17.87 ? 243 SER C CB 1 ATOM 4514 O OG . SER B 1 185 ? 36.951 -123.095 18.278 1.00 25.02 ? 243 SER C OG 1 ATOM 4515 N N . VAL B 1 186 ? 33.686 -124.709 19.334 1.00 21.59 ? 244 VAL C N 1 ATOM 4516 C CA . VAL B 1 186 ? 33.442 -125.519 20.522 1.00 18.81 ? 244 VAL C CA 1 ATOM 4517 C C . VAL B 1 186 ? 34.269 -126.792 20.412 1.00 16.78 ? 244 VAL C C 1 ATOM 4518 O O . VAL B 1 186 ? 34.103 -127.569 19.469 1.00 28.26 ? 244 VAL C O 1 ATOM 4519 C CB . VAL B 1 186 ? 31.946 -125.869 20.678 1.00 26.61 ? 244 VAL C CB 1 ATOM 4520 C CG1 . VAL B 1 186 ? 31.726 -126.832 21.843 1.00 27.92 ? 244 VAL C CG1 1 ATOM 4521 C CG2 . VAL B 1 186 ? 31.124 -124.603 20.874 1.00 23.85 ? 244 VAL C CG2 1 ATOM 4522 N N . LYS B 1 187 ? 35.164 -126.994 21.374 1.00 26.02 ? 245 LYS C N 1 ATOM 4523 C CA . LYS B 1 187 ? 36.092 -128.122 21.352 1.00 25.72 ? 245 LYS C CA 1 ATOM 4524 C C . LYS B 1 187 ? 36.841 -128.214 20.021 1.00 28.68 ? 245 LYS C C 1 ATOM 4525 O O . LYS B 1 187 ? 37.142 -129.308 19.544 1.00 30.95 ? 245 LYS C O 1 ATOM 4526 C CB . LYS B 1 187 ? 35.353 -129.436 21.628 1.00 29.42 ? 245 LYS C CB 1 ATOM 4527 C CG . LYS B 1 187 ? 34.773 -129.544 23.028 1.00 41.24 ? 245 LYS C CG 1 ATOM 4528 C CD . LYS B 1 187 ? 34.931 -130.959 23.578 1.00 63.82 ? 245 LYS C CD 1 ATOM 4529 C CE . LYS B 1 187 ? 34.014 -131.228 24.764 1.00 67.59 ? 245 LYS C CE 1 ATOM 4530 N NZ . LYS B 1 187 ? 33.679 -130.001 25.540 1.00 76.36 ? 245 LYS C NZ 1 ATOM 4531 N N . GLY B 1 188 ? 37.133 -127.061 19.426 1.00 24.10 ? 246 GLY C N 1 ATOM 4532 C CA . GLY B 1 188 ? 37.940 -127.003 18.220 1.00 27.43 ? 246 GLY C CA 1 ATOM 4533 C C . GLY B 1 188 ? 37.155 -127.040 16.920 1.00 27.35 ? 246 GLY C C 1 ATOM 4534 O O . GLY B 1 188 ? 37.750 -127.024 15.842 1.00 27.92 ? 246 GLY C O 1 ATOM 4535 N N . GLU B 1 189 ? 35.827 -127.080 17.018 1.00 27.61 ? 247 GLU C N 1 ATOM 4536 C CA . GLU B 1 189 ? 34.961 -127.155 15.839 1.00 30.59 ? 247 GLU C CA 1 ATOM 4537 C C . GLU B 1 189 ? 34.124 -125.889 15.651 1.00 27.20 ? 247 GLU C C 1 ATOM 4538 O O . GLU B 1 189 ? 33.377 -125.508 16.552 1.00 21.87 ? 247 GLU C O 1 ATOM 4539 C CB . GLU B 1 189 ? 34.031 -128.365 15.945 1.00 31.13 ? 247 GLU C CB 1 ATOM 4540 C CG . GLU B 1 189 ? 34.737 -129.703 15.792 1.00 48.78 ? 247 GLU C CG 1 ATOM 4541 C CD . GLU B 1 189 ? 35.375 -129.874 14.425 1.00 79.54 ? 247 GLU C CD 1 ATOM 4542 O OE1 . GLU B 1 189 ? 34.817 -129.354 13.434 1.00 57.92 ? 247 GLU C OE1 1 ATOM 4543 O OE2 . GLU B 1 189 ? 36.440 -130.523 14.343 1.00 62.89 ? 247 GLU C OE2 1 ATOM 4544 N N . PRO B 1 190 ? 34.230 -125.232 14.478 1.00 28.49 ? 248 PRO C N 1 ATOM 4545 C CA . PRO B 1 190 ? 35.100 -125.524 13.329 1.00 30.69 ? 248 PRO C CA 1 ATOM 4546 C C . PRO B 1 190 ? 36.544 -125.056 13.549 1.00 34.38 ? 248 PRO C C 1 ATOM 4547 O O . PRO B 1 190 ? 36.758 -124.073 14.259 1.00 29.00 ? 248 PRO C O 1 ATOM 4548 C CB . PRO B 1 190 ? 34.441 -124.748 12.188 1.00 28.25 ? 248 PRO C CB 1 ATOM 4549 C CG . PRO B 1 190 ? 33.767 -123.615 12.849 1.00 32.20 ? 248 PRO C CG 1 ATOM 4550 C CD . PRO B 1 190 ? 33.307 -124.120 14.188 1.00 27.30 ? 248 PRO C CD 1 ATOM 4551 N N . PRO B 1 191 ? 37.524 -125.747 12.944 1.00 32.01 ? 249 PRO C N 1 ATOM 4552 C CA . PRO B 1 191 ? 38.940 -125.457 13.210 1.00 30.73 ? 249 PRO C CA 1 ATOM 4553 C C . PRO B 1 191 ? 39.487 -124.203 12.525 1.00 31.93 ? 249 PRO C C 1 ATOM 4554 O O . PRO B 1 191 ? 40.625 -123.823 12.801 1.00 29.48 ? 249 PRO C O 1 ATOM 4555 C CB . PRO B 1 191 ? 39.653 -126.706 12.681 1.00 33.66 ? 249 PRO C CB 1 ATOM 4556 C CG . PRO B 1 191 ? 38.752 -127.242 11.631 1.00 46.22 ? 249 PRO C CG 1 ATOM 4557 C CD . PRO B 1 191 ? 37.355 -126.927 12.077 1.00 38.30 ? 249 PRO C CD 1 ATOM 4558 N N . ASP B 1 192 ? 38.705 -123.573 11.656 1.00 25.93 ? 250 ASP C N 1 ATOM 4559 C CA . ASP B 1 192 ? 39.162 -122.368 10.967 1.00 24.34 ? 250 ASP C CA 1 ATOM 4560 C C . ASP B 1 192 ? 39.137 -121.144 11.883 1.00 30.01 ? 250 ASP C C 1 ATOM 4561 O O . ASP B 1 192 ? 39.727 -120.112 11.561 1.00 27.57 ? 250 ASP C O 1 ATOM 4562 C CB . ASP B 1 192 ? 38.301 -122.092 9.729 1.00 36.38 ? 250 ASP C CB 1 ATOM 4563 C CG . ASP B 1 192 ? 38.478 -123.137 8.637 1.00 50.49 ? 250 ASP C CG 1 ATOM 4564 O OD1 . ASP B 1 192 ? 39.525 -123.818 8.612 1.00 34.98 ? 250 ASP C OD1 1 ATOM 4565 O OD2 . ASP B 1 192 ? 37.566 -123.269 7.793 1.00 33.56 ? 250 ASP C OD2 1 ATOM 4566 N N . LEU B 1 193 ? 38.464 -121.261 13.024 1.00 25.45 ? 251 LEU C N 1 ATOM 4567 C CA . LEU B 1 193 ? 38.212 -120.102 13.874 1.00 28.31 ? 251 LEU C CA 1 ATOM 4568 C C . LEU B 1 193 ? 39.296 -119.875 14.921 1.00 22.27 ? 251 LEU C C 1 ATOM 4569 O O . LEU B 1 193 ? 39.798 -120.812 15.542 1.00 19.83 ? 251 LEU C O 1 ATOM 4570 C CB . LEU B 1 193 ? 36.858 -120.245 14.565 1.00 20.35 ? 251 LEU C CB 1 ATOM 4571 C CG . LEU B 1 193 ? 35.667 -120.296 13.608 1.00 34.03 ? 251 LEU C CG 1 ATOM 4572 C CD1 . LEU B 1 193 ? 34.414 -120.619 14.378 1.00 27.03 ? 251 LEU C CD1 1 ATOM 4573 C CD2 . LEU B 1 193 ? 35.499 -118.984 12.849 1.00 35.12 ? 251 LEU C CD2 1 ATOM 4574 N N . THR B 1 194 ? 39.640 -118.607 15.105 1.00 19.81 ? 252 THR C N 1 ATOM 4575 C CA . THR B 1 194 ? 40.642 -118.198 16.076 1.00 22.76 ? 252 THR C CA 1 ATOM 4576 C C . THR B 1 194 ? 40.152 -118.410 17.502 1.00 19.27 ? 252 THR C C 1 ATOM 4577 O O . THR B 1 194 ? 40.850 -118.988 18.336 1.00 20.85 ? 252 THR C O 1 ATOM 4578 C CB . THR B 1 194 ? 41.000 -116.715 15.888 1.00 26.61 ? 252 THR C CB 1 ATOM 4579 O OG1 . THR B 1 194 ? 41.521 -116.514 14.569 1.00 27.81 ? 252 THR C OG1 1 ATOM 4580 C CG2 . THR B 1 194 ? 42.027 -116.262 16.911 1.00 26.26 ? 252 THR C CG2 1 ATOM 4581 N N . TRP B 1 195 ? 38.944 -117.932 17.770 1.00 17.02 ? 253 TRP C N 1 ATOM 4582 C CA . TRP B 1 195 ? 38.404 -117.930 19.121 1.00 16.20 ? 253 TRP C CA 1 ATOM 4583 C C . TRP B 1 195 ? 37.619 -119.183 19.481 1.00 22.08 ? 253 TRP C C 1 ATOM 4584 O O . TRP B 1 195 ? 36.829 -119.698 18.693 1.00 21.10 ? 253 TRP C O 1 ATOM 4585 C CB . TRP B 1 195 ? 37.505 -116.713 19.319 1.00 17.98 ? 253 TRP C CB 1 ATOM 4586 C CG . TRP B 1 195 ? 38.262 -115.460 19.571 1.00 26.71 ? 253 TRP C CG 1 ATOM 4587 C CD1 . TRP B 1 195 ? 38.508 -114.457 18.682 1.00 28.49 ? 253 TRP C CD1 1 ATOM 4588 C CD2 . TRP B 1 195 ? 38.880 -115.070 20.802 1.00 21.44 ? 253 TRP C CD2 1 ATOM 4589 N NE1 . TRP B 1 195 ? 39.241 -113.463 19.283 1.00 25.95 ? 253 TRP C NE1 1 ATOM 4590 C CE2 . TRP B 1 195 ? 39.483 -113.816 20.585 1.00 28.72 ? 253 TRP C CE2 1 ATOM 4591 C CE3 . TRP B 1 195 ? 38.983 -115.660 22.066 1.00 25.61 ? 253 TRP C CE3 1 ATOM 4592 C CZ2 . TRP B 1 195 ? 40.180 -113.140 21.586 1.00 29.39 ? 253 TRP C CZ2 1 ATOM 4593 C CZ3 . TRP B 1 195 ? 39.675 -114.987 23.058 1.00 26.92 ? 253 TRP C CZ3 1 ATOM 4594 C CH2 . TRP B 1 195 ? 40.264 -113.740 22.812 1.00 30.53 ? 253 TRP C CH2 1 ATOM 4595 N N . TYR B 1 196 ? 37.864 -119.662 20.692 1.00 18.33 ? 254 TYR C N 1 ATOM 4596 C CA . TYR B 1 196 ? 37.006 -120.643 21.341 1.00 15.00 ? 254 TYR C CA 1 ATOM 4597 C C . TYR B 1 196 ? 35.801 -119.907 21.908 1.00 18.39 ? 254 TYR C C 1 ATOM 4598 O O . TYR B 1 196 ? 35.880 -118.709 22.179 1.00 19.31 ? 254 TYR C O 1 ATOM 4599 C CB . TYR B 1 196 ? 37.759 -121.375 22.455 1.00 20.65 ? 254 TYR C CB 1 ATOM 4600 C CG . TYR B 1 196 ? 38.527 -120.431 23.352 1.00 17.59 ? 254 TYR C CG 1 ATOM 4601 C CD1 . TYR B 1 196 ? 37.892 -119.735 24.371 1.00 18.72 ? 254 TYR C CD1 1 ATOM 4602 C CD2 . TYR B 1 196 ? 39.884 -120.214 23.159 1.00 18.98 ? 254 TYR C CD2 1 ATOM 4603 C CE1 . TYR B 1 196 ? 38.591 -118.860 25.177 1.00 23.11 ? 254 TYR C CE1 1 ATOM 4604 C CE2 . TYR B 1 196 ? 40.589 -119.344 23.961 1.00 20.72 ? 254 TYR C CE2 1 ATOM 4605 C CZ . TYR B 1 196 ? 39.941 -118.670 24.967 1.00 23.60 ? 254 TYR C CZ 1 ATOM 4606 O OH . TYR B 1 196 ? 40.649 -117.804 25.764 1.00 24.04 ? 254 TYR C OH 1 ATOM 4607 N N . CYS B 1 197 ? 34.689 -120.607 22.091 1.00 16.67 ? 255 CYS C N 1 ATOM 4608 C CA . CYS B 1 197 ? 33.521 -119.996 22.712 1.00 15.74 ? 255 CYS C CA 1 ATOM 4609 C C . CYS B 1 197 ? 33.671 -119.975 24.227 1.00 15.32 ? 255 CYS C C 1 ATOM 4610 O O . CYS B 1 197 ? 34.422 -120.763 24.801 1.00 15.96 ? 255 CYS C O 1 ATOM 4611 C CB . CYS B 1 197 ? 32.253 -120.738 22.295 1.00 24.38 ? 255 CYS C CB 1 ATOM 4612 S SG . CYS B 1 197 ? 31.910 -120.535 20.522 1.00 28.59 ? 255 CYS C SG 1 ATOM 4613 N N . PHE B 1 198 ? 32.979 -119.046 24.873 1.00 11.34 ? 256 PHE C N 1 ATOM 4614 C CA . PHE B 1 198 ? 33.042 -118.947 26.321 1.00 20.11 ? 256 PHE C CA 1 ATOM 4615 C C . PHE B 1 198 ? 31.868 -118.158 26.856 1.00 13.30 ? 256 PHE C C 1 ATOM 4616 O O . PHE B 1 198 ? 31.231 -117.402 26.119 1.00 16.23 ? 256 PHE C O 1 ATOM 4617 C CB . PHE B 1 198 ? 34.361 -118.296 26.762 1.00 15.64 ? 256 PHE C CB 1 ATOM 4618 C CG . PHE B 1 198 ? 34.645 -116.973 26.097 1.00 14.48 ? 256 PHE C CG 1 ATOM 4619 C CD1 . PHE B 1 198 ? 34.077 -115.807 26.578 1.00 12.77 ? 256 PHE C CD1 1 ATOM 4620 C CD2 . PHE B 1 198 ? 35.489 -116.898 24.999 1.00 19.01 ? 256 PHE C CD2 1 ATOM 4621 C CE1 . PHE B 1 198 ? 34.338 -114.587 25.976 1.00 14.86 ? 256 PHE C CE1 1 ATOM 4622 C CE2 . PHE B 1 198 ? 35.754 -115.680 24.392 1.00 12.35 ? 256 PHE C CE2 1 ATOM 4623 C CZ . PHE B 1 198 ? 35.177 -114.525 24.882 1.00 20.32 ? 256 PHE C CZ 1 ATOM 4624 N N . LYS B 1 199 ? 31.571 -118.333 28.138 1.00 16.02 ? 257 LYS C N 1 ATOM 4625 C CA . LYS B 1 199 ? 30.491 -117.559 28.740 1.00 14.37 ? 257 LYS C CA 1 ATOM 4626 C C . LYS B 1 199 ? 30.605 -117.460 30.257 1.00 9.58 ? 257 LYS C C 1 ATOM 4627 O O . LYS B 1 199 ? 31.294 -118.260 30.884 1.00 14.58 ? 257 LYS C O 1 ATOM 4628 C CB . LYS B 1 199 ? 29.134 -118.160 28.362 1.00 26.44 ? 257 LYS C CB 1 ATOM 4629 C CG . LYS B 1 199 ? 28.893 -119.573 28.866 1.00 24.01 ? 257 LYS C CG 1 ATOM 4630 C CD . LYS B 1 199 ? 27.511 -120.061 28.454 1.00 37.25 ? 257 LYS C CD 1 ATOM 4631 C CE . LYS B 1 199 ? 27.269 -121.496 28.879 1.00 48.35 ? 257 LYS C CE 1 ATOM 4632 N NZ . LYS B 1 199 ? 25.890 -121.944 28.530 1.00 67.58 ? 257 LYS C NZ 1 ATOM 4633 N N . PRO B 1 200 ? 29.926 -116.467 30.852 1.00 11.65 ? 258 PRO C N 1 ATOM 4634 C CA . PRO B 1 200 ? 29.950 -116.327 32.309 1.00 18.41 ? 258 PRO C CA 1 ATOM 4635 C C . PRO B 1 200 ? 29.160 -117.429 33.002 1.00 24.78 ? 258 PRO C C 1 ATOM 4636 O O . PRO B 1 200 ? 28.101 -117.826 32.515 1.00 21.69 ? 258 PRO C O 1 ATOM 4637 C CB . PRO B 1 200 ? 29.289 -114.964 32.548 1.00 10.76 ? 258 PRO C CB 1 ATOM 4638 C CG . PRO B 1 200 ? 29.165 -114.323 31.212 1.00 17.36 ? 258 PRO C CG 1 ATOM 4639 C CD . PRO B 1 200 ? 29.076 -115.439 30.234 1.00 15.18 ? 258 PRO C CD 1 ATOM 4640 N N . ARG B 1 201 ? 29.636 -117.902 34.136 1.00 19.95 ? 259 ARG C N 1 ATOM 4641 C CA . ARG B 1 201 ? 28.963 -118.919 34.919 1.00 14.53 ? 259 ARG C CA 1 ATOM 4642 C C . ARG B 1 201 ? 29.148 -118.743 36.409 1.00 18.20 ? 259 ARG C C 1 ATOM 4643 O O . ARG B 1 201 ? 30.100 -118.156 36.863 1.00 16.57 ? 259 ARG C O 1 ATOM 4644 C CB . ARG B 1 201 ? 29.502 -120.317 34.620 1.00 18.95 ? 259 ARG C CB 1 ATOM 4645 C CG . ARG B 1 201 ? 29.300 -120.873 33.227 1.00 33.75 ? 259 ARG C CG 1 ATOM 4646 C CD . ARG B 1 201 ? 27.884 -121.352 33.017 1.00 26.49 ? 259 ARG C CD 1 ATOM 4647 N NE . ARG B 1 201 ? 27.043 -120.244 32.619 1.00 55.25 ? 259 ARG C NE 1 ATOM 4648 C CZ . ARG B 1 201 ? 25.809 -120.357 32.152 1.00 49.22 ? 259 ARG C CZ 1 ATOM 4649 N NH1 . ARG B 1 201 ? 25.148 -119.273 31.816 1.00 35.13 ? 259 ARG C NH1 1 ATOM 4650 N NH2 . ARG B 1 201 ? 25.242 -121.550 32.035 1.00 43.10 ? 259 ARG C NH2 1 ATOM 4651 N N . LYS B 1 202 ? 28.215 -119.303 37.155 1.00 17.10 ? 260 LYS C N 1 ATOM 4652 C CA . LYS B 1 202 ? 28.283 -119.409 38.590 1.00 18.00 ? 260 LYS C CA 1 ATOM 4653 C C . LYS B 1 202 ? 28.003 -120.898 38.742 1.00 22.70 ? 260 LYS C C 1 ATOM 4654 O O . LYS B 1 202 ? 27.217 -121.446 37.997 1.00 20.33 ? 260 LYS C O 1 ATOM 4655 C CB . LYS B 1 202 ? 27.282 -118.547 39.334 1.00 11.48 ? 260 LYS C CB 1 ATOM 4656 C CG . LYS B 1 202 ? 27.691 -117.106 39.484 1.00 15.99 ? 260 LYS C CG 1 ATOM 4657 C CD . LYS B 1 202 ? 27.031 -116.425 40.658 1.00 16.82 ? 260 LYS C CD 1 ATOM 4658 C CE . LYS B 1 202 ? 27.073 -114.927 40.496 1.00 17.65 ? 260 LYS C CE 1 ATOM 4659 N NZ . LYS B 1 202 ? 26.830 -114.186 41.750 1.00 18.46 ? 260 LYS C NZ 1 ATOM 4660 N N . SER B 1 203 ? 28.665 -121.547 39.680 1.00 19.08 ? 261 SER C N 1 ATOM 4661 C CA . SER B 1 203 ? 28.500 -122.984 39.879 1.00 17.74 ? 261 SER C CA 1 ATOM 4662 C C . SER B 1 203 ? 28.001 -123.289 41.285 1.00 24.02 ? 261 SER C C 1 ATOM 4663 O O . SER B 1 203 ? 28.320 -122.574 42.234 1.00 18.91 ? 261 SER C O 1 ATOM 4664 C CB . SER B 1 203 ? 29.821 -123.711 39.624 1.00 25.27 ? 261 SER C CB 1 ATOM 4665 O OG . SER B 1 203 ? 29.754 -125.059 40.058 1.00 40.42 ? 261 SER C OG 1 ATOM 4666 N N . VAL B 1 204 ? 27.220 -124.356 41.417 1.00 23.36 ? 262 VAL C N 1 ATOM 4667 C CA . VAL B 1 204 ? 26.649 -124.720 42.706 1.00 24.57 ? 262 VAL C CA 1 ATOM 4668 C C . VAL B 1 204 ? 27.726 -125.192 43.682 1.00 16.92 ? 262 VAL C C 1 ATOM 4669 O O . VAL B 1 204 ? 27.528 -125.128 44.894 1.00 23.95 ? 262 VAL C O 1 ATOM 4670 C CB . VAL B 1 204 ? 25.568 -125.822 42.564 1.00 30.16 ? 262 VAL C CB 1 ATOM 4671 C CG1 . VAL B 1 204 ? 24.376 -125.304 41.763 1.00 25.24 ? 262 VAL C CG1 1 ATOM 4672 C CG2 . VAL B 1 204 ? 26.143 -127.074 41.916 1.00 31.00 ? 262 VAL C CG2 1 ATOM 4673 N N . THR B 1 205 ? 28.859 -125.656 43.156 1.00 18.17 ? 263 THR C N 1 ATOM 4674 C CA . THR B 1 205 ? 29.962 -126.124 43.998 1.00 25.54 ? 263 THR C CA 1 ATOM 4675 C C . THR B 1 205 ? 31.305 -125.449 43.704 1.00 26.49 ? 263 THR C C 1 ATOM 4676 O O . THR B 1 205 ? 32.112 -125.264 44.612 1.00 27.93 ? 263 THR C O 1 ATOM 4677 C CB . THR B 1 205 ? 30.177 -127.643 43.852 1.00 31.31 ? 263 THR C CB 1 ATOM 4678 O OG1 . THR B 1 205 ? 30.415 -127.964 42.477 1.00 32.96 ? 263 THR C OG1 1 ATOM 4679 C CG2 . THR B 1 205 ? 28.969 -128.421 44.362 1.00 32.39 ? 263 THR C CG2 1 ATOM 4680 N N . GLU B 1 206 ? 31.544 -125.091 42.444 1.00 25.72 ? 264 GLU C N 1 ATOM 4681 C CA . GLU B 1 206 ? 32.876 -124.663 42.011 1.00 29.13 ? 264 GLU C CA 1 ATOM 4682 C C . GLU B 1 206 ? 33.085 -123.147 41.991 1.00 25.01 ? 264 GLU C C 1 ATOM 4683 O O . GLU B 1 206 ? 32.164 -122.381 41.712 1.00 19.76 ? 264 GLU C O 1 ATOM 4684 C CB . GLU B 1 206 ? 33.170 -125.216 40.613 1.00 32.53 ? 264 GLU C CB 1 ATOM 4685 C CG . GLU B 1 206 ? 33.078 -126.731 40.497 1.00 43.15 ? 264 GLU C CG 1 ATOM 4686 C CD . GLU B 1 206 ? 33.925 -127.452 41.530 1.00 54.94 ? 264 GLU C CD 1 ATOM 4687 O OE1 . GLU B 1 206 ? 33.349 -128.158 42.388 1.00 49.66 ? 264 GLU C OE1 1 ATOM 4688 O OE2 . GLU B 1 206 ? 35.165 -127.315 41.483 1.00 62.40 ? 264 GLU C OE2 1 ATOM 4689 N N . ASN B 1 207 ? 34.315 -122.736 42.291 1.00 23.87 ? 265 ASN C N 1 ATOM 4690 C CA . ASN B 1 207 ? 34.769 -121.357 42.099 1.00 19.05 ? 265 ASN C CA 1 ATOM 4691 C C . ASN B 1 207 ? 34.013 -120.299 42.907 1.00 15.66 ? 265 ASN C C 1 ATOM 4692 O O . ASN B 1 207 ? 33.899 -119.152 42.474 1.00 23.51 ? 265 ASN C O 1 ATOM 4693 C CB . ASN B 1 207 ? 34.698 -120.997 40.609 1.00 20.60 ? 265 ASN C CB 1 ATOM 4694 C CG . ASN B 1 207 ? 35.601 -121.865 39.757 1.00 26.93 ? 265 ASN C CG 1 ATOM 4695 O OD1 . ASN B 1 207 ? 36.737 -122.157 40.133 1.00 32.91 ? 265 ASN C OD1 1 ATOM 4696 N ND2 . ASN B 1 207 ? 35.099 -122.287 38.603 1.00 32.89 ? 265 ASN C ND2 1 ATOM 4697 N N . HIS B 1 208 ? 33.520 -120.669 44.085 1.00 24.34 ? 266 HIS C N 1 ATOM 4698 C CA . HIS B 1 208 ? 32.853 -119.705 44.960 1.00 27.38 ? 266 HIS C CA 1 ATOM 4699 C C . HIS B 1 208 ? 33.842 -118.680 45.513 1.00 28.59 ? 266 HIS C C 1 ATOM 4700 O O . HIS B 1 208 ? 33.450 -117.603 45.961 1.00 23.54 ? 266 HIS C O 1 ATOM 4701 C CB . HIS B 1 208 ? 32.158 -120.418 46.124 1.00 24.93 ? 266 HIS C CB 1 ATOM 4702 C CG . HIS B 1 208 ? 31.058 -121.340 45.701 1.00 30.00 ? 266 HIS C CG 1 ATOM 4703 N ND1 . HIS B 1 208 ? 30.393 -122.158 46.588 1.00 24.43 ? 266 HIS C ND1 1 ATOM 4704 C CD2 . HIS B 1 208 ? 30.505 -121.572 44.487 1.00 25.12 ? 266 HIS C CD2 1 ATOM 4705 C CE1 . HIS B 1 208 ? 29.479 -122.857 45.939 1.00 35.20 ? 266 HIS C CE1 1 ATOM 4706 N NE2 . HIS B 1 208 ? 29.526 -122.520 44.663 1.00 34.54 ? 266 HIS C NE2 1 ATOM 4707 N N . HIS B 1 209 ? 35.123 -119.031 45.471 1.00 22.78 ? 267 HIS C N 1 ATOM 4708 C CA A HIS B 1 209 ? 36.196 -118.213 46.027 0.43 27.17 ? 267 HIS C CA 1 ATOM 4709 C CA B HIS B 1 209 ? 36.164 -118.181 46.041 0.57 27.19 ? 267 HIS C CA 1 ATOM 4710 C C . HIS B 1 209 ? 36.717 -117.186 45.021 1.00 29.17 ? 267 HIS C C 1 ATOM 4711 O O . HIS B 1 209 ? 37.566 -116.360 45.353 1.00 23.22 ? 267 HIS C O 1 ATOM 4712 C CB A HIS B 1 209 ? 37.347 -119.111 46.506 0.43 25.98 ? 267 HIS C CB 1 ATOM 4713 C CB B HIS B 1 209 ? 37.294 -119.043 46.607 0.57 25.85 ? 267 HIS C CB 1 ATOM 4714 C CG A HIS B 1 209 ? 37.888 -120.033 45.453 0.43 34.24 ? 267 HIS C CG 1 ATOM 4715 C CG B HIS B 1 209 ? 36.862 -119.936 47.728 0.57 26.95 ? 267 HIS C CG 1 ATOM 4716 N ND1 A HIS B 1 209 ? 37.154 -121.071 44.918 0.43 25.68 ? 267 HIS C ND1 1 ATOM 4717 N ND1 B HIS B 1 209 ? 35.955 -119.537 48.687 0.57 28.72 ? 267 HIS C ND1 1 ATOM 4718 C CD2 A HIS B 1 209 ? 39.098 -120.081 44.849 0.43 29.54 ? 267 HIS C CD2 1 ATOM 4719 C CD2 B HIS B 1 209 ? 37.203 -121.209 48.039 0.57 28.70 ? 267 HIS C CD2 1 ATOM 4720 C CE1 A HIS B 1 209 ? 37.885 -121.710 44.023 0.43 33.10 ? 267 HIS C CE1 1 ATOM 4721 C CE1 B HIS B 1 209 ? 35.761 -120.524 49.544 0.57 33.28 ? 267 HIS C CE1 1 ATOM 4722 N NE2 A HIS B 1 209 ? 39.071 -121.130 43.963 0.43 32.85 ? 267 HIS C NE2 1 ATOM 4723 N NE2 B HIS B 1 209 ? 36.507 -121.550 49.173 0.57 28.85 ? 267 HIS C NE2 1 ATOM 4724 N N . LEU B 1 210 ? 36.220 -117.251 43.788 1.00 22.21 ? 268 LEU C N 1 ATOM 4725 C CA . LEU B 1 210 ? 36.599 -116.284 42.763 1.00 19.06 ? 268 LEU C CA 1 ATOM 4726 C C . LEU B 1 210 ? 35.618 -115.124 42.781 1.00 22.14 ? 268 LEU C C 1 ATOM 4727 O O . LEU B 1 210 ? 34.404 -115.332 42.825 1.00 26.48 ? 268 LEU C O 1 ATOM 4728 C CB . LEU B 1 210 ? 36.630 -116.922 41.373 1.00 20.31 ? 268 LEU C CB 1 ATOM 4729 C CG . LEU B 1 210 ? 37.613 -118.071 41.153 1.00 22.27 ? 268 LEU C CG 1 ATOM 4730 C CD1 . LEU B 1 210 ? 37.631 -118.443 39.682 1.00 23.29 ? 268 LEU C CD1 1 ATOM 4731 C CD2 . LEU B 1 210 ? 39.014 -117.714 41.635 1.00 26.97 ? 268 LEU C CD2 1 ATOM 4732 N N . ILE B 1 211 ? 36.148 -113.904 42.766 1.00 16.40 ? 269 ILE C N 1 ATOM 4733 C CA . ILE B 1 211 ? 35.310 -112.711 42.733 1.00 14.98 ? 269 ILE C CA 1 ATOM 4734 C C . ILE B 1 211 ? 35.674 -111.832 41.537 1.00 20.58 ? 269 ILE C C 1 ATOM 4735 O O . ILE B 1 211 ? 36.779 -111.297 41.463 1.00 17.01 ? 269 ILE C O 1 ATOM 4736 C CB . ILE B 1 211 ? 35.439 -111.910 44.041 1.00 22.25 ? 269 ILE C CB 1 ATOM 4737 C CG1 . ILE B 1 211 ? 35.103 -112.818 45.230 1.00 19.64 ? 269 ILE C CG1 1 ATOM 4738 C CG2 . ILE B 1 211 ? 34.522 -110.696 44.015 1.00 20.33 ? 269 ILE C CG2 1 ATOM 4739 C CD1 . ILE B 1 211 ? 35.244 -112.166 46.577 1.00 35.31 ? 269 ILE C CD1 1 ATOM 4740 N N . TYR B 1 212 ? 34.728 -111.697 40.611 1.00 19.56 ? 270 TYR C N 1 ATOM 4741 C CA . TYR B 1 212 ? 34.917 -110.928 39.383 1.00 15.41 ? 270 TYR C CA 1 ATOM 4742 C C . TYR B 1 212 ? 34.471 -109.485 39.578 1.00 19.38 ? 270 TYR C C 1 ATOM 4743 O O . TYR B 1 212 ? 33.445 -109.234 40.207 1.00 20.03 ? 270 TYR C O 1 ATOM 4744 C CB . TYR B 1 212 ? 34.124 -111.568 38.240 1.00 21.92 ? 270 TYR C CB 1 ATOM 4745 C CG . TYR B 1 212 ? 34.415 -111.023 36.859 1.00 15.30 ? 270 TYR C CG 1 ATOM 4746 C CD1 . TYR B 1 212 ? 33.825 -109.847 36.410 1.00 17.57 ? 270 TYR C CD1 1 ATOM 4747 C CD2 . TYR B 1 212 ? 35.262 -111.702 35.992 1.00 17.72 ? 270 TYR C CD2 1 ATOM 4748 C CE1 . TYR B 1 212 ? 34.084 -109.357 35.140 1.00 18.18 ? 270 TYR C CE1 1 ATOM 4749 C CE2 . TYR B 1 212 ? 35.524 -111.222 34.724 1.00 16.60 ? 270 TYR C CE2 1 ATOM 4750 C CZ . TYR B 1 212 ? 34.933 -110.050 34.303 1.00 21.85 ? 270 TYR C CZ 1 ATOM 4751 O OH . TYR B 1 212 ? 35.198 -109.572 33.040 1.00 21.96 ? 270 TYR C OH 1 ATOM 4752 N N . GLY B 1 213 ? 35.231 -108.536 39.041 1.00 15.18 ? 271 GLY C N 1 ATOM 4753 C CA . GLY B 1 213 ? 34.805 -107.148 39.082 1.00 13.98 ? 271 GLY C CA 1 ATOM 4754 C C . GLY B 1 213 ? 35.428 -106.286 38.006 1.00 12.84 ? 271 GLY C C 1 ATOM 4755 O O . GLY B 1 213 ? 36.479 -106.619 37.471 1.00 18.90 ? 271 GLY C O 1 ATOM 4756 N N . SER B 1 214 ? 34.777 -105.176 37.676 1.00 17.72 ? 272 SER C N 1 ATOM 4757 C CA . SER B 1 214 ? 35.416 -104.166 36.845 1.00 21.90 ? 272 SER C CA 1 ATOM 4758 C C . SER B 1 214 ? 36.453 -103.456 37.701 1.00 24.62 ? 272 SER C C 1 ATOM 4759 O O . SER B 1 214 ? 36.448 -103.597 38.919 1.00 20.85 ? 272 SER C O 1 ATOM 4760 C CB . SER B 1 214 ? 34.404 -103.167 36.295 1.00 18.00 ? 272 SER C CB 1 ATOM 4761 O OG . SER B 1 214 ? 34.208 -102.098 37.200 1.00 16.13 ? 272 SER C OG 1 ATOM 4762 N N . ALA B 1 215 ? 37.337 -102.699 37.084 1.00 20.76 ? 273 ALA C N 1 ATOM 4763 C CA . ALA B 1 215 ? 38.361 -101.986 37.827 1.00 21.06 ? 273 ALA C CA 1 ATOM 4764 C C . ALA B 1 215 ? 37.763 -100.909 38.713 1.00 25.98 ? 273 ALA C C 1 ATOM 4765 O O . ALA B 1 215 ? 38.359 -100.488 39.680 1.00 23.15 ? 273 ALA C O 1 ATOM 4766 C CB . ALA B 1 215 ? 39.352 -101.380 36.873 1.00 22.34 ? 273 ALA C CB 1 ATOM 4767 N N . TYR B 1 216 ? 36.570 -100.487 38.336 1.00 17.48 ? 274 TYR C N 1 ATOM 4768 C CA . TYR B 1 216 ? 35.849 -99.429 38.996 1.00 18.67 ? 274 TYR C CA 1 ATOM 4769 C C . TYR B 1 216 ? 35.244 -99.737 40.358 1.00 19.85 ? 274 TYR C C 1 ATOM 4770 O O . TYR B 1 216 ? 34.699 -98.861 40.980 1.00 29.60 ? 274 TYR C O 1 ATOM 4771 C CB . TYR B 1 216 ? 34.833 -98.806 38.036 1.00 20.17 ? 274 TYR C CB 1 ATOM 4772 C CG . TYR B 1 216 ? 35.557 -98.233 36.852 1.00 25.19 ? 274 TYR C CG 1 ATOM 4773 C CD1 . TYR B 1 216 ? 35.836 -99.004 35.738 1.00 19.88 ? 274 TYR C CD1 1 ATOM 4774 C CD2 . TYR B 1 216 ? 36.047 -96.952 36.888 1.00 21.77 ? 274 TYR C CD2 1 ATOM 4775 C CE1 . TYR B 1 216 ? 36.539 -98.490 34.679 1.00 26.12 ? 274 TYR C CE1 1 ATOM 4776 C CE2 . TYR B 1 216 ? 36.757 -96.429 35.840 1.00 18.29 ? 274 TYR C CE2 1 ATOM 4777 C CZ . TYR B 1 216 ? 37.002 -97.196 34.737 1.00 22.49 ? 274 TYR C CZ 1 ATOM 4778 O OH . TYR B 1 216 ? 37.704 -96.676 33.709 1.00 29.80 ? 274 TYR C OH 1 ATOM 4779 N N . VAL B 1 217 ? 35.359 -100.974 40.820 1.00 18.26 ? 275 VAL C N 1 ATOM 4780 C CA . VAL B 1 217 ? 34.964 -101.273 42.190 1.00 27.51 ? 275 VAL C CA 1 ATOM 4781 C C . VAL B 1 217 ? 36.083 -100.705 43.093 1.00 28.34 ? 275 VAL C C 1 ATOM 4782 O O . VAL B 1 217 ? 35.878 -100.456 44.256 1.00 22.47 ? 275 VAL C O 1 ATOM 4783 C CB . VAL B 1 217 ? 34.597 -102.763 42.482 1.00 31.41 ? 275 VAL C CB 1 ATOM 4784 C CG1 . VAL B 1 217 ? 34.359 -103.598 41.237 1.00 29.78 ? 275 VAL C CG1 1 ATOM 4785 C CG2 . VAL B 1 217 ? 35.485 -103.441 43.501 1.00 21.42 ? 275 VAL C CG2 1 ATOM 4786 N N . GLY B 1 218 ? 37.259 -100.525 42.504 1.00 25.79 ? 276 GLY C N 1 ATOM 4787 C CA . GLY B 1 218 ? 38.428 -99.988 43.149 1.00 28.47 ? 276 GLY C CA 1 ATOM 4788 C C . GLY B 1 218 ? 38.514 -98.470 43.167 1.00 28.58 ? 276 GLY C C 1 ATOM 4789 O O . GLY B 1 218 ? 39.408 -97.935 43.772 1.00 28.83 ? 276 GLY C O 1 ATOM 4790 N N . GLU B 1 219 ? 37.584 -97.778 42.518 1.00 28.69 ? 277 GLU C N 1 ATOM 4791 C CA . GLU B 1 219 ? 37.608 -96.316 42.524 1.00 33.22 ? 277 GLU C CA 1 ATOM 4792 C C . GLU B 1 219 ? 37.453 -95.836 43.965 1.00 38.64 ? 277 GLU C C 1 ATOM 4793 O O . GLU B 1 219 ? 38.152 -94.935 44.409 1.00 39.32 ? 277 GLU C O 1 ATOM 4794 C CB . GLU B 1 219 ? 36.517 -95.734 41.629 1.00 30.42 ? 277 GLU C CB 1 ATOM 4795 C CG . GLU B 1 219 ? 36.690 -94.249 41.357 1.00 37.94 ? 277 GLU C CG 1 ATOM 4796 C CD . GLU B 1 219 ? 35.709 -93.720 40.333 1.00 47.83 ? 277 GLU C CD 1 ATOM 4797 O OE1 . GLU B 1 219 ? 35.810 -92.535 39.966 1.00 59.68 ? 277 GLU C OE1 1 ATOM 4798 O OE2 . GLU B 1 219 ? 34.837 -94.487 39.891 1.00 57.08 ? 277 GLU C OE2 1 ATOM 4799 N N . ASN B 1 220 ? 36.498 -96.420 44.668 1.00 32.47 ? 278 ASN C N 1 ATOM 4800 C CA . ASN B 1 220 ? 36.219 -96.137 46.064 1.00 38.45 ? 278 ASN C CA 1 ATOM 4801 C C . ASN B 1 220 ? 36.223 -97.517 46.668 1.00 32.79 ? 278 ASN C C 1 ATOM 4802 O O . ASN B 1 220 ? 35.206 -98.153 46.846 1.00 34.99 ? 278 ASN C O 1 ATOM 4803 C CB . ASN B 1 220 ? 34.903 -95.405 46.226 1.00 34.01 ? 278 ASN C CB 1 ATOM 4804 C CG . ASN B 1 220 ? 34.993 -93.970 45.776 1.00 35.32 ? 278 ASN C CG 1 ATOM 4805 O OD1 . ASN B 1 220 ? 34.428 -93.587 44.774 1.00 40.37 ? 278 ASN C OD1 1 ATOM 4806 N ND2 . ASN B 1 220 ? 35.733 -93.175 46.513 1.00 44.48 ? 278 ASN C ND2 1 ATOM 4807 N N . PRO B 1 221 ? 37.413 -97.988 47.002 1.00 37.11 ? 279 PRO C N 1 ATOM 4808 C CA . PRO B 1 221 ? 37.634 -99.362 47.464 1.00 28.42 ? 279 PRO C CA 1 ATOM 4809 C C . PRO B 1 221 ? 36.889 -99.827 48.707 1.00 31.67 ? 279 PRO C C 1 ATOM 4810 O O . PRO B 1 221 ? 36.747 -101.023 48.860 1.00 36.59 ? 279 PRO C O 1 ATOM 4811 C CB . PRO B 1 221 ? 39.148 -99.425 47.671 1.00 27.87 ? 279 PRO C CB 1 ATOM 4812 C CG . PRO B 1 221 ? 39.563 -98.017 47.867 1.00 33.46 ? 279 PRO C CG 1 ATOM 4813 C CD . PRO B 1 221 ? 38.649 -97.194 47.021 1.00 35.30 ? 279 PRO C CD 1 ATOM 4814 N N . ASP B 1 222 ? 36.458 -98.945 49.588 1.00 29.84 ? 280 ASP C N 1 ATOM 4815 C CA . ASP B 1 222 ? 35.745 -99.403 50.761 1.00 32.38 ? 280 ASP C CA 1 ATOM 4816 C C . ASP B 1 222 ? 34.216 -99.320 50.617 1.00 29.47 ? 280 ASP C C 1 ATOM 4817 O O . ASP B 1 222 ? 33.493 -99.811 51.460 1.00 33.03 ? 280 ASP C O 1 ATOM 4818 C CB . ASP B 1 222 ? 36.199 -98.615 51.984 1.00 34.04 ? 280 ASP C CB 1 ATOM 4819 C CG . ASP B 1 222 ? 37.682 -98.761 52.259 1.00 43.31 ? 280 ASP C CG 1 ATOM 4820 O OD1 . ASP B 1 222 ? 38.253 -99.814 51.975 1.00 35.24 ? 280 ASP C OD1 1 ATOM 4821 O OD2 . ASP B 1 222 ? 38.282 -97.811 52.778 1.00 49.86 ? 280 ASP C OD2 1 ATOM 4822 N N . ALA B 1 223 ? 33.730 -98.704 49.553 1.00 28.20 ? 281 ALA C N 1 ATOM 4823 C CA . ALA B 1 223 ? 32.295 -98.501 49.382 1.00 31.38 ? 281 ALA C CA 1 ATOM 4824 C C . ALA B 1 223 ? 31.515 -99.817 49.327 1.00 27.16 ? 281 ALA C C 1 ATOM 4825 O O . ALA B 1 223 ? 30.483 -99.962 49.991 1.00 35.16 ? 281 ALA C O 1 ATOM 4826 C CB . ALA B 1 223 ? 32.037 -97.691 48.124 1.00 26.95 ? 281 ALA C CB 1 ATOM 4827 N N . PHE B 1 224 ? 32.021 -100.772 48.550 1.00 26.54 ? 282 PHE C N 1 ATOM 4828 C CA . PHE B 1 224 ? 31.310 -102.025 48.295 1.00 28.75 ? 282 PHE C CA 1 ATOM 4829 C C . PHE B 1 224 ? 30.907 -102.727 49.589 1.00 35.38 ? 282 PHE C C 1 ATOM 4830 O O . PHE B 1 224 ? 29.932 -103.475 49.617 1.00 29.07 ? 282 PHE C O 1 ATOM 4831 C CB . PHE B 1 224 ? 32.170 -102.966 47.443 1.00 24.46 ? 282 PHE C CB 1 ATOM 4832 C CG . PHE B 1 224 ? 33.201 -103.729 48.227 1.00 30.32 ? 282 PHE C CG 1 ATOM 4833 C CD1 . PHE B 1 224 ? 32.891 -104.956 48.790 1.00 29.66 ? 282 PHE C CD1 1 ATOM 4834 C CD2 . PHE B 1 224 ? 34.481 -103.225 48.392 1.00 32.05 ? 282 PHE C CD2 1 ATOM 4835 C CE1 . PHE B 1 224 ? 33.832 -105.661 49.511 1.00 29.16 ? 282 PHE C CE1 1 ATOM 4836 C CE2 . PHE B 1 224 ? 35.429 -103.929 49.112 1.00 30.01 ? 282 PHE C CE2 1 ATOM 4837 C CZ . PHE B 1 224 ? 35.104 -105.149 49.671 1.00 35.30 ? 282 PHE C CZ 1 ATOM 4838 N N . ILE B 1 225 ? 31.666 -102.478 50.651 1.00 29.27 ? 283 ILE C N 1 ATOM 4839 C CA . ILE B 1 225 ? 31.400 -103.070 51.955 1.00 30.09 ? 283 ILE C CA 1 ATOM 4840 C C . ILE B 1 225 ? 29.991 -102.751 52.450 1.00 34.66 ? 283 ILE C C 1 ATOM 4841 O O . ILE B 1 225 ? 29.362 -103.581 53.109 1.00 43.59 ? 283 ILE C O 1 ATOM 4842 C CB . ILE B 1 225 ? 32.429 -102.582 52.998 1.00 38.24 ? 283 ILE C CB 1 ATOM 4843 C CG1 . ILE B 1 225 ? 33.812 -103.155 52.680 1.00 44.70 ? 283 ILE C CG1 1 ATOM 4844 C CG2 . ILE B 1 225 ? 32.017 -102.985 54.409 1.00 38.50 ? 283 ILE C CG2 1 ATOM 4845 C CD1 . ILE B 1 225 ? 34.939 -102.533 53.484 1.00 40.77 ? 283 ILE C CD1 1 ATOM 4846 N N . SER B 1 226 ? 29.496 -101.559 52.125 1.00 33.37 ? 284 SER C N 1 ATOM 4847 C CA . SER B 1 226 ? 28.215 -101.099 52.660 1.00 41.10 ? 284 SER C CA 1 ATOM 4848 C C . SER B 1 226 ? 27.153 -100.875 51.582 1.00 37.46 ? 284 SER C C 1 ATOM 4849 O O . SER B 1 226 ? 25.959 -100.853 51.879 1.00 39.15 ? 284 SER C O 1 ATOM 4850 C CB . SER B 1 226 ? 28.419 -99.804 53.450 1.00 45.78 ? 284 SER C CB 1 ATOM 4851 O OG . SER B 1 226 ? 28.926 -98.774 52.619 1.00 47.09 ? 284 SER C OG 1 ATOM 4852 N N . LYS B 1 227 ? 27.592 -100.718 50.336 1.00 34.85 ? 285 LYS C N 1 ATOM 4853 C CA . LYS B 1 227 ? 26.703 -100.340 49.239 1.00 33.62 ? 285 LYS C CA 1 ATOM 4854 C C . LYS B 1 227 ? 26.354 -101.501 48.309 1.00 35.23 ? 285 LYS C C 1 ATOM 4855 O O . LYS B 1 227 ? 25.512 -101.353 47.422 1.00 37.44 ? 285 LYS C O 1 ATOM 4856 C CB . LYS B 1 227 ? 27.342 -99.211 48.429 1.00 36.02 ? 285 LYS C CB 1 ATOM 4857 C CG . LYS B 1 227 ? 27.281 -97.856 49.117 1.00 41.35 ? 285 LYS C CG 1 ATOM 4858 C CD . LYS B 1 227 ? 28.318 -96.890 48.563 1.00 44.48 ? 285 LYS C CD 1 ATOM 4859 C CE . LYS B 1 227 ? 27.727 -95.507 48.323 1.00 56.35 ? 285 LYS C CE 1 ATOM 4860 N NZ . LYS B 1 227 ? 27.063 -94.946 49.534 1.00 54.56 ? 285 LYS C NZ 1 ATOM 4861 N N . CYS B 1 228 ? 27.000 -102.647 48.508 1.00 27.89 ? 286 CYS C N 1 ATOM 4862 C CA . CYS B 1 228 ? 26.760 -103.819 47.666 1.00 31.00 ? 286 CYS C CA 1 ATOM 4863 C C . CYS B 1 228 ? 26.223 -104.998 48.481 1.00 30.99 ? 286 CYS C C 1 ATOM 4864 O O . CYS B 1 228 ? 26.589 -105.169 49.643 1.00 34.19 ? 286 CYS C O 1 ATOM 4865 C CB . CYS B 1 228 ? 28.046 -104.217 46.943 1.00 21.74 ? 286 CYS C CB 1 ATOM 4866 S SG . CYS B 1 228 ? 28.651 -102.941 45.807 1.00 40.32 ? 286 CYS C SG 1 ATOM 4867 N N . PRO B 1 229 ? 25.347 -105.819 47.873 1.00 33.02 ? 287 PRO C N 1 ATOM 4868 C CA . PRO B 1 229 ? 24.766 -106.961 48.585 1.00 27.05 ? 287 PRO C CA 1 ATOM 4869 C C . PRO B 1 229 ? 25.661 -108.194 48.486 1.00 27.77 ? 287 PRO C C 1 ATOM 4870 O O . PRO B 1 229 ? 25.323 -109.156 47.797 1.00 28.67 ? 287 PRO C O 1 ATOM 4871 C CB . PRO B 1 229 ? 23.440 -107.167 47.856 1.00 31.71 ? 287 PRO C CB 1 ATOM 4872 C CG . PRO B 1 229 ? 23.776 -106.823 46.427 1.00 30.25 ? 287 PRO C CG 1 ATOM 4873 C CD . PRO B 1 229 ? 24.860 -105.755 46.482 1.00 26.21 ? 287 PRO C CD 1 ATOM 4874 N N . ASN B 1 230 ? 26.795 -108.156 49.178 1.00 20.94 ? 288 ASN C N 1 ATOM 4875 C CA . ASN B 1 230 ? 27.831 -109.167 49.011 1.00 22.92 ? 288 ASN C CA 1 ATOM 4876 C C . ASN B 1 230 ? 27.412 -110.562 49.463 1.00 24.00 ? 288 ASN C C 1 ATOM 4877 O O . ASN B 1 230 ? 27.852 -111.558 48.889 1.00 25.75 ? 288 ASN C O 1 ATOM 4878 C CB . ASN B 1 230 ? 29.092 -108.744 49.765 1.00 21.75 ? 288 ASN C CB 1 ATOM 4879 C CG . ASN B 1 230 ? 29.639 -107.418 49.276 1.00 23.36 ? 288 ASN C CG 1 ATOM 4880 O OD1 . ASN B 1 230 ? 30.078 -107.300 48.132 1.00 25.29 ? 288 ASN C OD1 1 ATOM 4881 N ND2 . ASN B 1 230 ? 29.617 -106.410 50.141 1.00 25.98 ? 288 ASN C ND2 1 ATOM 4882 N N . GLN B 1 231 ? 26.562 -110.629 50.483 1.00 16.60 ? 289 GLN C N 1 ATOM 4883 C CA . GLN B 1 231 ? 26.139 -111.909 51.044 1.00 20.97 ? 289 GLN C CA 1 ATOM 4884 C C . GLN B 1 231 ? 24.656 -112.189 50.823 1.00 16.23 ? 289 GLN C C 1 ATOM 4885 O O . GLN B 1 231 ? 23.840 -111.274 50.709 1.00 22.97 ? 289 GLN C O 1 ATOM 4886 C CB . GLN B 1 231 ? 26.452 -111.957 52.541 1.00 24.08 ? 289 GLN C CB 1 ATOM 4887 C CG . GLN B 1 231 ? 27.805 -112.577 52.859 1.00 33.99 ? 289 GLN C CG 1 ATOM 4888 C CD . GLN B 1 231 ? 28.961 -111.783 52.286 1.00 38.01 ? 289 GLN C CD 1 ATOM 4889 O OE1 . GLN B 1 231 ? 29.697 -112.265 51.424 1.00 32.70 ? 289 GLN C OE1 1 ATOM 4890 N NE2 . GLN B 1 231 ? 29.127 -110.557 52.766 1.00 30.37 ? 289 GLN C NE2 1 ATOM 4891 N N . ALA B 1 232 ? 24.325 -113.473 50.756 1.00 19.34 ? 290 ALA C N 1 ATOM 4892 C CA . ALA B 1 232 ? 22.940 -113.914 50.730 1.00 19.35 ? 290 ALA C CA 1 ATOM 4893 C C . ALA B 1 232 ? 22.246 -113.520 52.032 1.00 23.87 ? 290 ALA C C 1 ATOM 4894 O O . ALA B 1 232 ? 22.892 -113.404 53.073 1.00 25.36 ? 290 ALA C O 1 ATOM 4895 C CB . ALA B 1 232 ? 22.871 -115.414 50.524 1.00 16.77 ? 290 ALA C CB 1 ATOM 4896 N N . LEU B 1 233 ? 20.933 -113.315 51.964 1.00 22.95 ? 291 LEU C N 1 ATOM 4897 C CA . LEU B 1 233 ? 20.143 -112.923 53.128 1.00 24.13 ? 291 LEU C CA 1 ATOM 4898 C C . LEU B 1 233 ? 19.276 -114.083 53.613 1.00 29.54 ? 291 LEU C C 1 ATOM 4899 O O . LEU B 1 233 ? 18.286 -114.439 52.973 1.00 19.75 ? 291 LEU C O 1 ATOM 4900 C CB . LEU B 1 233 ? 19.271 -111.713 52.786 1.00 24.57 ? 291 LEU C CB 1 ATOM 4901 C CG . LEU B 1 233 ? 18.445 -111.113 53.925 1.00 28.44 ? 291 LEU C CG 1 ATOM 4902 C CD1 . LEU B 1 233 ? 19.343 -110.548 55.013 1.00 30.48 ? 291 LEU C CD1 1 ATOM 4903 C CD2 . LEU B 1 233 ? 17.513 -110.035 53.391 1.00 34.57 ? 291 LEU C CD2 1 ATOM 4904 N N . ARG B 1 234 ? 19.650 -114.665 54.748 1.00 21.78 ? 292 ARG C N 1 ATOM 4905 C CA . ARG B 1 234 ? 18.947 -115.827 55.285 1.00 26.11 ? 292 ARG C CA 1 ATOM 4906 C C . ARG B 1 234 ? 17.691 -115.426 56.047 1.00 28.18 ? 292 ARG C C 1 ATOM 4907 O O . ARG B 1 234 ? 17.684 -114.423 56.757 1.00 20.18 ? 292 ARG C O 1 ATOM 4908 C CB . ARG B 1 234 ? 19.862 -116.625 56.214 1.00 27.70 ? 292 ARG C CB 1 ATOM 4909 C CG . ARG B 1 234 ? 19.405 -118.051 56.446 1.00 36.55 ? 292 ARG C CG 1 ATOM 4910 C CD . ARG B 1 234 ? 19.811 -118.543 57.822 1.00 50.66 ? 292 ARG C CD 1 ATOM 4911 N NE . ARG B 1 234 ? 19.321 -119.895 58.083 1.00 59.12 ? 292 ARG C NE 1 ATOM 4912 C CZ . ARG B 1 234 ? 20.026 -121.011 57.909 1.00 67.02 ? 292 ARG C CZ 1 ATOM 4913 N NH1 . ARG B 1 234 ? 21.280 -120.966 57.473 1.00 63.39 ? 292 ARG C NH1 1 ATOM 4914 N NH2 . ARG B 1 234 ? 19.471 -122.185 58.178 1.00 59.12 ? 292 ARG C NH2 1 ATOM 4915 N N . GLY B 1 235 ? 16.631 -116.215 55.897 1.00 23.11 ? 293 GLY C N 1 ATOM 4916 C CA . GLY B 1 235 ? 15.443 -116.064 56.720 1.00 22.55 ? 293 GLY C CA 1 ATOM 4917 C C . GLY B 1 235 ? 14.460 -115.003 56.262 1.00 21.98 ? 293 GLY C C 1 ATOM 4918 O O . GLY B 1 235 ? 13.481 -114.731 56.954 1.00 24.80 ? 293 GLY C O 1 ATOM 4919 N N . TYR B 1 236 ? 14.710 -114.407 55.099 1.00 25.81 ? 294 TYR C N 1 ATOM 4920 C CA . TYR B 1 236 ? 13.812 -113.398 54.550 1.00 19.13 ? 294 TYR C CA 1 ATOM 4921 C C . TYR B 1 236 ? 13.597 -113.588 53.051 1.00 27.13 ? 294 TYR C C 1 ATOM 4922 O O . TYR B 1 236 ? 14.477 -114.071 52.338 1.00 21.37 ? 294 TYR C O 1 ATOM 4923 C CB . TYR B 1 236 ? 14.352 -111.990 54.815 1.00 27.01 ? 294 TYR C CB 1 ATOM 4924 C CG . TYR B 1 236 ? 14.387 -111.597 56.274 1.00 28.35 ? 294 TYR C CG 1 ATOM 4925 C CD1 . TYR B 1 236 ? 13.281 -111.019 56.884 1.00 29.71 ? 294 TYR C CD1 1 ATOM 4926 C CD2 . TYR B 1 236 ? 15.530 -111.793 57.039 1.00 29.29 ? 294 TYR C CD2 1 ATOM 4927 C CE1 . TYR B 1 236 ? 13.309 -110.655 58.217 1.00 27.14 ? 294 TYR C CE1 1 ATOM 4928 C CE2 . TYR B 1 236 ? 15.568 -111.432 58.373 1.00 30.49 ? 294 TYR C CE2 1 ATOM 4929 C CZ . TYR B 1 236 ? 14.455 -110.863 58.956 1.00 28.14 ? 294 TYR C CZ 1 ATOM 4930 O OH . TYR B 1 236 ? 14.490 -110.502 60.282 1.00 34.41 ? 294 TYR C OH 1 ATOM 4931 N N . ARG B 1 237 ? 12.407 -113.208 52.598 1.00 24.39 ? 295 ARG C N 1 ATOM 4932 C CA . ARG B 1 237 ? 12.066 -113.139 51.183 1.00 24.53 ? 295 ARG C CA 1 ATOM 4933 C C . ARG B 1 237 ? 12.056 -111.685 50.752 1.00 24.85 ? 295 ARG C C 1 ATOM 4934 O O . ARG B 1 237 ? 11.427 -110.851 51.411 1.00 26.49 ? 295 ARG C O 1 ATOM 4935 C CB . ARG B 1 237 ? 10.690 -113.746 50.906 1.00 24.30 ? 295 ARG C CB 1 ATOM 4936 C CG . ARG B 1 237 ? 10.509 -115.199 51.290 1.00 23.87 ? 295 ARG C CG 1 ATOM 4937 C CD . ARG B 1 237 ? 9.100 -115.647 50.927 1.00 22.94 ? 295 ARG C CD 1 ATOM 4938 N NE . ARG B 1 237 ? 8.847 -117.049 51.240 1.00 27.26 ? 295 ARG C NE 1 ATOM 4939 C CZ . ARG B 1 237 ? 7.810 -117.740 50.777 1.00 35.21 ? 295 ARG C CZ 1 ATOM 4940 N NH1 . ARG B 1 237 ? 7.654 -119.013 51.112 1.00 27.28 ? 295 ARG C NH1 1 ATOM 4941 N NH2 . ARG B 1 237 ? 6.929 -117.162 49.972 1.00 25.92 ? 295 ARG C NH2 1 ATOM 4942 N N . PHE B 1 238 ? 12.743 -111.384 49.654 1.00 21.33 ? 296 PHE C N 1 ATOM 4943 C CA . PHE B 1 238 ? 12.659 -110.066 49.040 1.00 22.81 ? 296 PHE C CA 1 ATOM 4944 C C . PHE B 1 238 ? 11.207 -109.736 48.740 1.00 22.35 ? 296 PHE C C 1 ATOM 4945 O O . PHE B 1 238 ? 10.450 -110.596 48.287 1.00 23.31 ? 296 PHE C O 1 ATOM 4946 C CB . PHE B 1 238 ? 13.475 -110.006 47.743 1.00 21.56 ? 296 PHE C CB 1 ATOM 4947 C CG . PHE B 1 238 ? 14.963 -109.906 47.947 1.00 23.74 ? 296 PHE C CG 1 ATOM 4948 C CD1 . PHE B 1 238 ? 15.497 -109.250 49.045 1.00 18.81 ? 296 PHE C CD1 1 ATOM 4949 C CD2 . PHE B 1 238 ? 15.829 -110.465 47.021 1.00 17.25 ? 296 PHE C CD2 1 ATOM 4950 C CE1 . PHE B 1 238 ? 16.865 -109.161 49.217 1.00 26.34 ? 296 PHE C CE1 1 ATOM 4951 C CE2 . PHE B 1 238 ? 17.196 -110.379 47.187 1.00 23.19 ? 296 PHE C CE2 1 ATOM 4952 C CZ . PHE B 1 238 ? 17.715 -109.726 48.287 1.00 23.32 ? 296 PHE C CZ 1 ATOM 4953 N N . GLY B 1 239 ? 10.818 -108.493 48.998 1.00 26.60 ? 297 GLY C N 1 ATOM 4954 C CA . GLY B 1 239 ? 9.475 -108.055 48.687 1.00 24.47 ? 297 GLY C CA 1 ATOM 4955 C C . GLY B 1 239 ? 9.375 -106.591 48.322 1.00 30.07 ? 297 GLY C C 1 ATOM 4956 O O . GLY B 1 239 ? 10.288 -105.795 48.584 1.00 33.73 ? 297 GLY C O 1 ATOM 4957 N N . VAL B 1 240 ? 8.243 -106.242 47.717 1.00 27.35 ? 298 VAL C N 1 ATOM 4958 C CA . VAL B 1 240 ? 7.943 -104.860 47.375 1.00 30.14 ? 298 VAL C CA 1 ATOM 4959 C C . VAL B 1 240 ? 6.790 -104.365 48.239 1.00 34.99 ? 298 VAL C C 1 ATOM 4960 O O . VAL B 1 240 ? 5.849 -105.107 48.528 1.00 39.19 ? 298 VAL C O 1 ATOM 4961 C CB . VAL B 1 240 ? 7.592 -104.698 45.882 1.00 34.18 ? 298 VAL C CB 1 ATOM 4962 C CG1 . VAL B 1 240 ? 8.767 -105.138 45.017 1.00 28.90 ? 298 VAL C CG1 1 ATOM 4963 C CG2 . VAL B 1 240 ? 6.346 -105.488 45.527 1.00 43.74 ? 298 VAL C CG2 1 ATOM 4964 N N . TRP B 1 241 ? 6.856 -103.109 48.640 1.00 39.15 ? 299 TRP C N 1 ATOM 4965 C CA . TRP B 1 241 ? 5.830 -102.543 49.484 1.00 40.85 ? 299 TRP C CA 1 ATOM 4966 C C . TRP B 1 241 ? 4.684 -102.032 48.642 1.00 38.74 ? 299 TRP C C 1 ATOM 4967 O O . TRP B 1 241 ? 4.828 -101.090 47.906 1.00 44.04 ? 299 TRP C O 1 ATOM 4968 C CB . TRP B 1 241 ? 6.420 -101.397 50.293 1.00 41.75 ? 299 TRP C CB 1 ATOM 4969 C CG . TRP B 1 241 ? 5.502 -100.845 51.312 1.00 48.18 ? 299 TRP C CG 1 ATOM 4970 C CD1 . TRP B 1 241 ? 4.808 -99.693 51.238 1.00 42.60 ? 299 TRP C CD1 1 ATOM 4971 C CD2 . TRP B 1 241 ? 5.175 -101.429 52.569 1.00 45.70 ? 299 TRP C CD2 1 ATOM 4972 N NE1 . TRP B 1 241 ? 4.071 -99.511 52.368 1.00 49.37 ? 299 TRP C NE1 1 ATOM 4973 C CE2 . TRP B 1 241 ? 4.276 -100.572 53.202 1.00 50.57 ? 299 TRP C CE2 1 ATOM 4974 C CE3 . TRP B 1 241 ? 5.559 -102.595 53.219 1.00 43.90 ? 299 TRP C CE3 1 ATOM 4975 C CZ2 . TRP B 1 241 ? 3.756 -100.838 54.449 1.00 54.10 ? 299 TRP C CZ2 1 ATOM 4976 C CZ3 . TRP B 1 241 ? 5.045 -102.856 54.449 1.00 49.19 ? 299 TRP C CZ3 1 ATOM 4977 C CH2 . TRP B 1 241 ? 4.154 -101.984 55.057 1.00 50.07 ? 299 TRP C CH2 1 ATOM 4978 N N . LYS B 1 242 ? 3.545 -102.686 48.757 1.00 41.28 ? 300 LYS C N 1 ATOM 4979 C CA . LYS B 1 242 ? 2.365 -102.311 48.010 1.00 47.81 ? 300 LYS C CA 1 ATOM 4980 C C . LYS B 1 242 ? 1.087 -102.328 48.820 1.00 52.40 ? 300 LYS C C 1 ATOM 4981 O O . LYS B 1 242 ? 0.798 -103.275 49.523 1.00 46.95 ? 300 LYS C O 1 ATOM 4982 C CB . LYS B 1 242 ? 2.181 -103.236 46.818 1.00 50.72 ? 300 LYS C CB 1 ATOM 4983 C CG . LYS B 1 242 ? 2.709 -102.695 45.510 1.00 75.44 ? 300 LYS C CG 1 ATOM 4984 C CD . LYS B 1 242 ? 2.555 -103.729 44.412 1.00 80.25 ? 300 LYS C CD 1 ATOM 4985 C CE . LYS B 1 242 ? 3.024 -103.200 43.070 1.00 99.66 ? 300 LYS C CE 1 ATOM 4986 N NZ . LYS B 1 242 ? 2.979 -104.251 42.016 1.00 83.35 ? 300 LYS C NZ 1 ATOM 4987 N N . LYS B 1 243 ? 0.312 -101.269 48.687 1.00 59.33 ? 301 LYS C N 1 ATOM 4988 C CA . LYS B 1 243 ? -0.967 -101.185 49.348 1.00 56.32 ? 301 LYS C CA 1 ATOM 4989 C C . LYS B 1 243 ? -0.968 -101.444 50.846 1.00 60.39 ? 301 LYS C C 1 ATOM 4990 O O . LYS B 1 243 ? -1.787 -102.193 51.347 1.00 52.07 ? 301 LYS C O 1 ATOM 4991 C CB . LYS B 1 243 ? -1.998 -102.045 48.619 1.00 74.75 ? 301 LYS C CB 1 ATOM 4992 C CG . LYS B 1 243 ? -2.671 -101.299 47.476 1.00 78.31 ? 301 LYS C CG 1 ATOM 4993 C CD . LYS B 1 243 ? -3.560 -102.193 46.635 1.00 80.11 ? 301 LYS C CD 1 ATOM 4994 C CE . LYS B 1 243 ? -2.827 -102.760 45.426 1.00 89.77 ? 301 LYS C CE 1 ATOM 4995 N NZ . LYS B 1 243 ? -2.036 -103.984 45.724 1.00 92.04 ? 301 LYS C NZ 1 ATOM 4996 N N . GLY B 1 244 ? -0.037 -100.831 51.553 1.00 51.89 ? 302 GLY C N 1 ATOM 4997 C CA . GLY B 1 244 ? 0.010 -100.972 52.992 1.00 51.03 ? 302 GLY C CA 1 ATOM 4998 C C . GLY B 1 244 ? 0.693 -102.221 53.514 1.00 48.98 ? 302 GLY C C 1 ATOM 4999 O O . GLY B 1 244 ? 0.752 -102.413 54.730 1.00 52.03 ? 302 GLY C O 1 ATOM 5000 N N . ARG B 1 245 ? 1.205 -103.076 52.630 1.00 44.42 ? 303 ARG C N 1 ATOM 5001 C CA . ARG B 1 245 ? 1.914 -104.261 53.107 1.00 44.53 ? 303 ARG C CA 1 ATOM 5002 C C . ARG B 1 245 ? 3.030 -104.731 52.182 1.00 42.00 ? 303 ARG C C 1 ATOM 5003 O O . ARG B 1 245 ? 3.148 -104.292 51.035 1.00 39.12 ? 303 ARG C O 1 ATOM 5004 C CB . ARG B 1 245 ? 0.926 -105.407 53.338 1.00 40.59 ? 303 ARG C CB 1 ATOM 5005 C CG . ARG B 1 245 ? 0.066 -105.747 52.142 1.00 46.78 ? 303 ARG C CG 1 ATOM 5006 C CD . ARG B 1 245 ? -0.691 -107.043 52.370 1.00 47.57 ? 303 ARG C CD 1 ATOM 5007 N NE . ARG B 1 245 ? -1.174 -107.612 51.112 1.00 42.70 ? 303 ARG C NE 1 ATOM 5008 C CZ . ARG B 1 245 ? -0.950 -108.857 50.694 1.00 52.06 ? 303 ARG C CZ 1 ATOM 5009 N NH1 . ARG B 1 245 ? -0.247 -109.716 51.425 1.00 43.44 ? 303 ARG C NH1 1 ATOM 5010 N NH2 . ARG B 1 245 ? -1.438 -109.251 49.527 1.00 53.24 ? 303 ARG C NH2 1 ATOM 5011 N N . CYS B 1 246 ? 3.852 -105.633 52.712 1.00 37.31 ? 304 CYS C N 1 ATOM 5012 C CA . CYS B 1 246 ? 5.005 -106.145 51.992 1.00 39.39 ? 304 CYS C CA 1 ATOM 5013 C C . CYS B 1 246 ? 4.631 -107.399 51.212 1.00 35.55 ? 304 CYS C C 1 ATOM 5014 O O . CYS B 1 246 ? 4.266 -108.416 51.801 1.00 34.70 ? 304 CYS C O 1 ATOM 5015 C CB . CYS B 1 246 ? 6.152 -106.450 52.959 1.00 44.27 ? 304 CYS C CB 1 ATOM 5016 S SG . CYS B 1 246 ? 7.727 -106.804 52.138 1.00 58.58 ? 304 CYS C SG 1 ATOM 5017 N N . LEU B 1 247 ? 4.715 -107.314 49.887 1.00 32.85 ? 305 LEU C N 1 ATOM 5018 C CA . LEU B 1 247 ? 4.454 -108.461 49.026 1.00 29.19 ? 305 LEU C CA 1 ATOM 5019 C C . LEU B 1 247 ? 5.759 -109.092 48.571 1.00 32.34 ? 305 LEU C C 1 ATOM 5020 O O . LEU B 1 247 ? 6.549 -108.462 47.861 1.00 30.65 ? 305 LEU C O 1 ATOM 5021 C CB . LEU B 1 247 ? 3.632 -108.056 47.800 1.00 31.58 ? 305 LEU C CB 1 ATOM 5022 C CG . LEU B 1 247 ? 2.347 -107.254 48.016 1.00 42.67 ? 305 LEU C CG 1 ATOM 5023 C CD1 . LEU B 1 247 ? 1.451 -107.370 46.789 1.00 40.92 ? 305 LEU C CD1 1 ATOM 5024 C CD2 . LEU B 1 247 ? 1.603 -107.701 49.259 1.00 49.68 ? 305 LEU C CD2 1 ATOM 5025 N N . ASP B 1 248 ? 5.985 -110.337 48.979 1.00 23.00 ? 306 ASP C N 1 ATOM 5026 C CA . ASP B 1 248 ? 7.138 -111.079 48.496 1.00 31.22 ? 306 ASP C CA 1 ATOM 5027 C C . ASP B 1 248 ? 6.907 -111.387 47.023 1.00 35.67 ? 306 ASP C C 1 ATOM 5028 O O . ASP B 1 248 ? 5.782 -111.285 46.533 1.00 34.80 ? 306 ASP C O 1 ATOM 5029 C CB . ASP B 1 248 ? 7.362 -112.357 49.310 1.00 31.19 ? 306 ASP C CB 1 ATOM 5030 C CG . ASP B 1 248 ? 6.296 -113.404 49.070 1.00 46.33 ? 306 ASP C CG 1 ATOM 5031 O OD1 . ASP B 1 248 ? 5.181 -113.257 49.615 1.00 54.54 ? 306 ASP C OD1 1 ATOM 5032 O OD2 . ASP B 1 248 ? 6.581 -114.383 48.349 1.00 35.72 ? 306 ASP C OD2 1 ATOM 5033 N N . TYR B 1 249 ? 7.972 -111.753 46.318 1.00 26.44 ? 307 TYR C N 1 ATOM 5034 C CA . TYR B 1 249 ? 7.923 -111.871 44.864 1.00 29.09 ? 307 TYR C CA 1 ATOM 5035 C C . TYR B 1 249 ? 6.845 -112.834 44.359 1.00 31.14 ? 307 TYR C C 1 ATOM 5036 O O . TYR B 1 249 ? 6.289 -112.625 43.282 1.00 29.22 ? 307 TYR C O 1 ATOM 5037 C CB . TYR B 1 249 ? 9.291 -112.313 44.329 1.00 27.07 ? 307 TYR C CB 1 ATOM 5038 C CG . TYR B 1 249 ? 10.381 -111.257 44.396 1.00 19.81 ? 307 TYR C CG 1 ATOM 5039 C CD1 . TYR B 1 249 ? 10.075 -109.904 44.494 1.00 21.18 ? 307 TYR C CD1 1 ATOM 5040 C CD2 . TYR B 1 249 ? 11.721 -111.619 44.343 1.00 23.16 ? 307 TYR C CD2 1 ATOM 5041 C CE1 . TYR B 1 249 ? 11.071 -108.947 44.544 1.00 27.76 ? 307 TYR C CE1 1 ATOM 5042 C CE2 . TYR B 1 249 ? 12.723 -110.669 44.394 1.00 26.95 ? 307 TYR C CE2 1 ATOM 5043 C CZ . TYR B 1 249 ? 12.393 -109.337 44.491 1.00 24.47 ? 307 TYR C CZ 1 ATOM 5044 O OH . TYR B 1 249 ? 13.391 -108.393 44.540 1.00 26.77 ? 307 TYR C OH 1 ATOM 5045 N N . THR B 1 250 ? 6.538 -113.875 45.127 1.00 23.78 ? 308 THR C N 1 ATOM 5046 C CA . THR B 1 250 ? 5.592 -114.888 44.662 1.00 31.82 ? 308 THR C CA 1 ATOM 5047 C C . THR B 1 250 ? 4.162 -114.354 44.562 1.00 29.85 ? 308 THR C C 1 ATOM 5048 O O . THR B 1 250 ? 3.302 -115.001 43.968 1.00 37.54 ? 308 THR C O 1 ATOM 5049 C CB . THR B 1 250 ? 5.586 -116.126 45.577 1.00 27.61 ? 308 THR C CB 1 ATOM 5050 O OG1 . THR B 1 250 ? 5.120 -115.764 46.882 1.00 37.86 ? 308 THR C OG1 1 ATOM 5051 C CG2 . THR B 1 250 ? 6.980 -116.725 45.677 1.00 32.94 ? 308 THR C CG2 1 ATOM 5052 N N . GLU B 1 251 ? 3.913 -113.180 45.139 1.00 31.10 ? 309 GLU C N 1 ATOM 5053 C CA . GLU B 1 251 ? 2.595 -112.550 45.066 1.00 39.04 ? 309 GLU C CA 1 ATOM 5054 C C . GLU B 1 251 ? 2.489 -111.596 43.877 1.00 42.48 ? 309 GLU C C 1 ATOM 5055 O O . GLU B 1 251 ? 1.445 -110.979 43.663 1.00 41.28 ? 309 GLU C O 1 ATOM 5056 C CB . GLU B 1 251 ? 2.283 -111.791 46.359 1.00 41.00 ? 309 GLU C CB 1 ATOM 5057 C CG . GLU B 1 251 ? 1.918 -112.685 47.539 1.00 50.27 ? 309 GLU C CG 1 ATOM 5058 C CD . GLU B 1 251 ? 1.130 -111.949 48.610 1.00 75.27 ? 309 GLU C CD 1 ATOM 5059 O OE1 . GLU B 1 251 ? -0.015 -111.533 48.330 1.00 66.20 ? 309 GLU C OE1 1 ATOM 5060 O OE2 . GLU B 1 251 ? 1.654 -111.786 49.733 1.00 69.19 ? 309 GLU C OE2 1 ATOM 5061 N N . LEU B 1 252 ? 3.571 -111.476 43.113 1.00 40.54 ? 310 LEU C N 1 ATOM 5062 C CA . LEU B 1 252 ? 3.595 -110.605 41.943 1.00 37.40 ? 310 LEU C CA 1 ATOM 5063 C C . LEU B 1 252 ? 3.447 -111.433 40.670 1.00 38.39 ? 310 LEU C C 1 ATOM 5064 O O . LEU B 1 252 ? 4.004 -112.527 40.564 1.00 42.58 ? 310 LEU C O 1 ATOM 5065 C CB . LEU B 1 252 ? 4.888 -109.791 41.909 1.00 44.26 ? 310 LEU C CB 1 ATOM 5066 C CG . LEU B 1 252 ? 5.221 -109.048 43.206 1.00 46.18 ? 310 LEU C CG 1 ATOM 5067 C CD1 . LEU B 1 252 ? 6.582 -108.381 43.103 1.00 36.98 ? 310 LEU C CD1 1 ATOM 5068 C CD2 . LEU B 1 252 ? 4.145 -108.023 43.542 1.00 41.13 ? 310 LEU C CD2 1 ATOM 5069 N N . THR B 1 253 ? 2.691 -110.909 39.711 1.00 47.18 ? 311 THR C N 1 ATOM 5070 C CA . THR B 1 253 ? 2.377 -111.645 38.490 1.00 56.86 ? 311 THR C CA 1 ATOM 5071 C C . THR B 1 253 ? 3.617 -111.930 37.645 1.00 35.52 ? 311 THR C C 1 ATOM 5072 O O . THR B 1 253 ? 3.837 -113.063 37.215 1.00 42.40 ? 311 THR C O 1 ATOM 5073 C CB . THR B 1 253 ? 1.357 -110.874 37.625 1.00 72.24 ? 311 THR C CB 1 ATOM 5074 O OG1 . THR B 1 253 ? 0.160 -110.652 38.378 1.00 78.22 ? 311 THR C OG1 1 ATOM 5075 C CG2 . THR B 1 253 ? 1.014 -111.652 36.354 1.00 60.78 ? 311 THR C CG2 1 ATOM 5076 N N . ASP B 1 254 ? 4.424 -110.900 37.412 1.00 37.18 ? 312 ASP C N 1 ATOM 5077 C CA . ASP B 1 254 ? 5.562 -111.003 36.502 1.00 48.16 ? 312 ASP C CA 1 ATOM 5078 C C . ASP B 1 254 ? 6.735 -111.792 37.090 1.00 37.30 ? 312 ASP C C 1 ATOM 5079 O O . ASP B 1 254 ? 7.765 -111.958 36.438 1.00 37.35 ? 312 ASP C O 1 ATOM 5080 C CB . ASP B 1 254 ? 6.033 -109.603 36.102 1.00 54.51 ? 312 ASP C CB 1 ATOM 5081 C CG . ASP B 1 254 ? 4.983 -108.837 35.319 1.00 69.23 ? 312 ASP C CG 1 ATOM 5082 O OD1 . ASP B 1 254 ? 4.348 -109.436 34.425 1.00 71.16 ? 312 ASP C OD1 1 ATOM 5083 O OD2 . ASP B 1 254 ? 4.790 -107.635 35.600 1.00 69.46 ? 312 ASP C OD2 1 ATOM 5084 N N . THR B 1 255 ? 6.578 -112.276 38.317 1.00 34.19 ? 313 THR C N 1 ATOM 5085 C CA . THR B 1 255 ? 7.619 -113.068 38.962 1.00 28.55 ? 313 THR C CA 1 ATOM 5086 C C . THR B 1 255 ? 7.762 -114.423 38.288 1.00 34.68 ? 313 THR C C 1 ATOM 5087 O O . THR B 1 255 ? 6.766 -115.047 37.919 1.00 31.36 ? 313 THR C O 1 ATOM 5088 C CB . THR B 1 255 ? 7.314 -113.269 40.459 1.00 26.47 ? 313 THR C CB 1 ATOM 5089 O OG1 . THR B 1 255 ? 7.438 -112.014 41.136 1.00 26.34 ? 313 THR C OG1 1 ATOM 5090 C CG2 . THR B 1 255 ? 8.268 -114.281 41.097 1.00 21.48 ? 313 THR C CG2 1 ATOM 5091 N N . VAL B 1 256 ? 9.004 -114.878 38.137 1.00 22.17 ? 314 VAL C N 1 ATOM 5092 C CA . VAL B 1 256 ? 9.263 -116.187 37.543 1.00 24.02 ? 314 VAL C CA 1 ATOM 5093 C C . VAL B 1 256 ? 9.547 -117.206 38.640 1.00 27.48 ? 314 VAL C C 1 ATOM 5094 O O . VAL B 1 256 ? 10.442 -117.011 39.462 1.00 25.64 ? 314 VAL C O 1 ATOM 5095 C CB . VAL B 1 256 ? 10.445 -116.145 36.557 1.00 25.67 ? 314 VAL C CB 1 ATOM 5096 C CG1 . VAL B 1 256 ? 10.791 -117.550 36.070 1.00 29.91 ? 314 VAL C CG1 1 ATOM 5097 C CG2 . VAL B 1 256 ? 10.111 -115.243 35.372 1.00 27.90 ? 314 VAL C CG2 1 ATOM 5098 N N . ILE B 1 257 ? 8.781 -118.294 38.638 1.00 24.44 ? 315 ILE C N 1 ATOM 5099 C CA . ILE B 1 257 ? 8.919 -119.346 39.637 1.00 17.10 ? 315 ILE C CA 1 ATOM 5100 C C . ILE B 1 257 ? 9.432 -120.615 38.980 1.00 20.02 ? 315 ILE C C 1 ATOM 5101 O O . ILE B 1 257 ? 8.849 -121.097 38.006 1.00 27.59 ? 315 ILE C O 1 ATOM 5102 C CB . ILE B 1 257 ? 7.578 -119.621 40.352 1.00 21.83 ? 315 ILE C CB 1 ATOM 5103 C CG1 . ILE B 1 257 ? 7.166 -118.385 41.158 1.00 27.29 ? 315 ILE C CG1 1 ATOM 5104 C CG2 . ILE B 1 257 ? 7.688 -120.847 41.265 1.00 24.98 ? 315 ILE C CG2 1 ATOM 5105 C CD1 . ILE B 1 257 ? 5.858 -118.523 41.911 1.00 43.67 ? 315 ILE C CD1 1 ATOM 5106 N N . GLU B 1 258 ? 10.524 -121.152 39.517 1.00 18.69 ? 316 GLU C N 1 ATOM 5107 C CA . GLU B 1 258 ? 11.139 -122.348 38.950 1.00 18.83 ? 316 GLU C CA 1 ATOM 5108 C C . GLU B 1 258 ? 11.464 -123.396 40.011 1.00 29.07 ? 316 GLU C C 1 ATOM 5109 O O . GLU B 1 258 ? 11.775 -123.067 41.156 1.00 32.86 ? 316 GLU C O 1 ATOM 5110 C CB . GLU B 1 258 ? 12.415 -121.973 38.188 1.00 21.87 ? 316 GLU C CB 1 ATOM 5111 C CG . GLU B 1 258 ? 12.238 -120.774 37.262 1.00 35.01 ? 316 GLU C CG 1 ATOM 5112 C CD . GLU B 1 258 ? 13.440 -120.521 36.368 1.00 43.48 ? 316 GLU C CD 1 ATOM 5113 O OE1 . GLU B 1 258 ? 13.444 -119.489 35.666 1.00 38.22 ? 316 GLU C OE1 1 ATOM 5114 O OE2 . GLU B 1 258 ? 14.377 -121.348 36.360 1.00 37.57 ? 316 GLU C OE2 1 ATOM 5115 N N . ARG B 1 259 ? 11.382 -124.661 39.612 1.00 23.14 ? 317 ARG C N 1 ATOM 5116 C CA . ARG B 1 259 ? 11.766 -125.772 40.471 1.00 25.76 ? 317 ARG C CA 1 ATOM 5117 C C . ARG B 1 259 ? 13.275 -125.801 40.672 1.00 24.27 ? 317 ARG C C 1 ATOM 5118 O O . ARG B 1 259 ? 14.036 -125.502 39.751 1.00 23.19 ? 317 ARG C O 1 ATOM 5119 C CB . ARG B 1 259 ? 11.305 -127.103 39.873 1.00 19.88 ? 317 ARG C CB 1 ATOM 5120 C CG . ARG B 1 259 ? 9.798 -127.295 39.837 1.00 32.40 ? 317 ARG C CG 1 ATOM 5121 C CD . ARG B 1 259 ? 9.425 -128.546 39.053 0.72 30.62 ? 317 ARG C CD 1 ATOM 5122 N NE . ARG B 1 259 ? 9.775 -128.427 37.638 0.65 36.74 ? 317 ARG C NE 1 ATOM 5123 C CZ . ARG B 1 259 ? 9.036 -127.796 36.730 0.83 32.33 ? 317 ARG C CZ 1 ATOM 5124 N NH1 . ARG B 1 259 ? 9.442 -127.741 35.469 1.00 31.83 ? 317 ARG C NH1 1 ATOM 5125 N NH2 . ARG B 1 259 ? 7.894 -127.215 37.076 1.00 26.17 ? 317 ARG C NH2 1 ATOM 5126 N N . VAL B 1 260 ? 13.702 -126.162 41.877 1.00 23.28 ? 318 VAL C N 1 ATOM 5127 C CA . VAL B 1 260 ? 15.115 -126.372 42.163 1.00 25.53 ? 318 VAL C CA 1 ATOM 5128 C C . VAL B 1 260 ? 15.272 -127.509 43.159 1.00 24.77 ? 318 VAL C C 1 ATOM 5129 O O . VAL B 1 260 ? 14.376 -127.766 43.961 1.00 29.14 ? 318 VAL C O 1 ATOM 5130 C CB . VAL B 1 260 ? 15.789 -125.109 42.731 1.00 25.30 ? 318 VAL C CB 1 ATOM 5131 C CG1 . VAL B 1 260 ? 15.823 -124.004 41.689 1.00 23.39 ? 318 VAL C CG1 1 ATOM 5132 C CG2 . VAL B 1 260 ? 15.077 -124.641 43.995 1.00 17.95 ? 318 VAL C CG2 1 ATOM 5133 N N . GLU B 1 261 ? 16.417 -128.180 43.101 1.00 22.42 ? 319 GLU C N 1 ATOM 5134 C CA . GLU B 1 261 ? 16.729 -129.261 44.028 1.00 32.95 ? 319 GLU C CA 1 ATOM 5135 C C . GLU B 1 261 ? 17.507 -128.750 45.241 1.00 32.66 ? 319 GLU C C 1 ATOM 5136 O O . GLU B 1 261 ? 17.709 -129.483 46.208 1.00 39.18 ? 319 GLU C O 1 ATOM 5137 C CB . GLU B 1 261 ? 17.536 -130.351 43.321 1.00 33.26 ? 319 GLU C CB 1 ATOM 5138 C CG . GLU B 1 261 ? 16.903 -130.865 42.037 1.00 51.69 ? 319 GLU C CG 1 ATOM 5139 C CD . GLU B 1 261 ? 17.829 -131.780 41.262 0.49 70.19 ? 319 GLU C CD 1 ATOM 5140 O OE1 . GLU B 1 261 ? 17.755 -133.011 41.461 0.79 77.79 ? 319 GLU C OE1 1 ATOM 5141 O OE2 . GLU B 1 261 ? 18.633 -131.268 40.454 0.65 62.92 ? 319 GLU C OE2 1 ATOM 5142 N N . SER B 1 262 ? 17.947 -127.495 45.181 1.00 28.86 ? 320 SER C N 1 ATOM 5143 C CA . SER B 1 262 ? 18.727 -126.899 46.262 1.00 26.55 ? 320 SER C CA 1 ATOM 5144 C C . SER B 1 262 ? 18.764 -125.378 46.141 1.00 30.49 ? 320 SER C C 1 ATOM 5145 O O . SER B 1 262 ? 18.496 -124.823 45.078 1.00 24.20 ? 320 SER C O 1 ATOM 5146 C CB . SER B 1 262 ? 20.151 -127.450 46.255 1.00 31.19 ? 320 SER C CB 1 ATOM 5147 O OG . SER B 1 262 ? 20.859 -126.979 45.120 1.00 29.35 ? 320 SER C OG 1 ATOM 5148 N N . LYS B 1 263 ? 19.112 -124.709 47.234 1.00 25.72 ? 321 LYS C N 1 ATOM 5149 C CA . LYS B 1 263 ? 19.153 -123.250 47.263 1.00 28.84 ? 321 LYS C CA 1 ATOM 5150 C C . LYS B 1 263 ? 20.295 -122.684 46.406 1.00 11.02 ? 321 LYS C C 1 ATOM 5151 O O . LYS B 1 263 ? 20.192 -121.581 45.844 1.00 22.22 ? 321 LYS C O 1 ATOM 5152 C CB . LYS B 1 263 ? 19.275 -122.766 48.712 1.00 30.37 ? 321 LYS C CB 1 ATOM 5153 C CG . LYS B 1 263 ? 20.389 -123.428 49.521 1.00 34.95 ? 321 LYS C CG 1 ATOM 5154 C CD . LYS B 1 263 ? 20.625 -122.729 50.861 1.00 35.89 ? 321 LYS C CD 1 ATOM 5155 C CE . LYS B 1 263 ? 19.378 -122.685 51.739 1.00 46.46 ? 321 LYS C CE 1 ATOM 5156 N NZ . LYS B 1 263 ? 18.907 -124.039 52.146 1.00 53.54 ? 321 LYS C NZ 1 ATOM 5157 N N . ALA B 1 264 ? 21.374 -123.451 46.294 1.00 17.39 ? 322 ALA C N 1 ATOM 5158 C CA . ALA B 1 264 ? 22.508 -123.061 45.466 1.00 22.66 ? 322 ALA C CA 1 ATOM 5159 C C . ALA B 1 264 ? 22.094 -122.918 44.001 1.00 22.32 ? 322 ALA C C 1 ATOM 5160 O O . ALA B 1 264 ? 22.572 -122.026 43.297 1.00 19.37 ? 322 ALA C O 1 ATOM 5161 C CB . ALA B 1 264 ? 23.631 -124.071 45.602 1.00 18.19 ? 322 ALA C CB 1 ATOM 5162 N N . GLN B 1 265 ? 21.203 -123.795 43.545 1.00 25.17 ? 323 GLN C N 1 ATOM 5163 C CA . GLN B 1 265 ? 20.681 -123.710 42.184 1.00 19.74 ? 323 GLN C CA 1 ATOM 5164 C C . GLN B 1 265 ? 19.925 -122.401 41.971 1.00 16.64 ? 323 GLN C C 1 ATOM 5165 O O . GLN B 1 265 ? 20.028 -121.782 40.913 1.00 18.82 ? 323 GLN C O 1 ATOM 5166 C CB . GLN B 1 265 ? 19.768 -124.897 41.876 1.00 27.50 ? 323 GLN C CB 1 ATOM 5167 C CG . GLN B 1 265 ? 20.512 -126.175 41.533 1.00 33.31 ? 323 GLN C CG 1 ATOM 5168 C CD . GLN B 1 265 ? 19.582 -127.297 41.109 1.00 50.54 ? 323 GLN C CD 1 ATOM 5169 O OE1 . GLN B 1 265 ? 18.362 -127.137 41.091 1.00 39.52 ? 323 GLN C OE1 1 ATOM 5170 N NE2 . GLN B 1 265 ? 20.158 -128.442 40.762 1.00 45.84 ? 323 GLN C NE2 1 ATOM 5171 N N . CYS B 1 266 ? 19.165 -121.985 42.981 1.00 18.22 ? 324 CYS C N 1 ATOM 5172 C CA . CYS B 1 266 ? 18.452 -120.709 42.933 1.00 19.78 ? 324 CYS C CA 1 ATOM 5173 C C . CYS B 1 266 ? 19.441 -119.548 42.886 1.00 19.49 ? 324 CYS C C 1 ATOM 5174 O O . CYS B 1 266 ? 19.298 -118.613 42.080 1.00 19.37 ? 324 CYS C O 1 ATOM 5175 C CB . CYS B 1 266 ? 17.528 -120.558 44.142 1.00 15.75 ? 324 CYS C CB 1 ATOM 5176 S SG . CYS B 1 266 ? 16.450 -119.112 44.066 1.00 29.59 ? 324 CYS C SG 1 ATOM 5177 N N . TRP B 1 267 ? 20.442 -119.612 43.760 1.00 21.49 ? 325 TRP C N 1 ATOM 5178 C CA . TRP B 1 267 ? 21.523 -118.630 43.741 1.00 20.21 ? 325 TRP C CA 1 ATOM 5179 C C . TRP B 1 267 ? 22.144 -118.521 42.348 1.00 19.27 ? 325 TRP C C 1 ATOM 5180 O O . TRP B 1 267 ? 22.309 -117.422 41.829 1.00 14.50 ? 325 TRP C O 1 ATOM 5181 C CB . TRP B 1 267 ? 22.591 -118.988 44.777 1.00 19.10 ? 325 TRP C CB 1 ATOM 5182 C CG . TRP B 1 267 ? 23.826 -118.139 44.691 1.00 20.09 ? 325 TRP C CG 1 ATOM 5183 C CD1 . TRP B 1 267 ? 23.936 -116.810 44.998 1.00 15.94 ? 325 TRP C CD1 1 ATOM 5184 C CD2 . TRP B 1 267 ? 25.128 -118.563 44.277 1.00 17.27 ? 325 TRP C CD2 1 ATOM 5185 N NE1 . TRP B 1 267 ? 25.227 -116.384 44.794 1.00 17.28 ? 325 TRP C NE1 1 ATOM 5186 C CE2 . TRP B 1 267 ? 25.978 -117.441 44.352 1.00 20.40 ? 325 TRP C CE2 1 ATOM 5187 C CE3 . TRP B 1 267 ? 25.658 -119.783 43.847 1.00 19.88 ? 325 TRP C CE3 1 ATOM 5188 C CZ2 . TRP B 1 267 ? 27.326 -117.504 44.015 1.00 11.41 ? 325 TRP C CZ2 1 ATOM 5189 C CZ3 . TRP B 1 267 ? 26.998 -119.842 43.513 1.00 23.02 ? 325 TRP C CZ3 1 ATOM 5190 C CH2 . TRP B 1 267 ? 27.816 -118.711 43.597 1.00 18.45 ? 325 TRP C CH2 1 ATOM 5191 N N . VAL B 1 268 ? 22.475 -119.657 41.740 1.00 19.55 ? 326 VAL C N 1 ATOM 5192 C CA . VAL B 1 268 ? 22.977 -119.664 40.366 1.00 17.59 ? 326 VAL C CA 1 ATOM 5193 C C . VAL B 1 268 ? 21.961 -119.082 39.380 1.00 26.26 ? 326 VAL C C 1 ATOM 5194 O O . VAL B 1 268 ? 22.318 -118.331 38.464 1.00 20.13 ? 326 VAL C O 1 ATOM 5195 C CB . VAL B 1 268 ? 23.347 -121.090 39.923 1.00 18.50 ? 326 VAL C CB 1 ATOM 5196 C CG1 . VAL B 1 268 ? 23.617 -121.150 38.419 1.00 22.75 ? 326 VAL C CG1 1 ATOM 5197 C CG2 . VAL B 1 268 ? 24.562 -121.579 40.696 1.00 20.08 ? 326 VAL C CG2 1 ATOM 5198 N N . LYS B 1 269 ? 20.694 -119.442 39.556 1.00 20.38 ? 327 LYS C N 1 ATOM 5199 C CA . LYS B 1 269 ? 19.639 -118.941 38.682 1.00 17.65 ? 327 LYS C CA 1 ATOM 5200 C C . LYS B 1 269 ? 19.495 -117.425 38.739 1.00 19.10 ? 327 LYS C C 1 ATOM 5201 O O . LYS B 1 269 ? 19.202 -116.800 37.719 1.00 19.57 ? 327 LYS C O 1 ATOM 5202 C CB . LYS B 1 269 ? 18.299 -119.591 39.026 1.00 23.10 ? 327 LYS C CB 1 ATOM 5203 C CG . LYS B 1 269 ? 18.108 -120.971 38.409 1.00 25.12 ? 327 LYS C CG 1 ATOM 5204 C CD . LYS B 1 269 ? 16.755 -121.564 38.783 1.00 29.36 ? 327 LYS C CD 1 ATOM 5205 C CE . LYS B 1 269 ? 16.592 -122.981 38.248 1.00 32.94 ? 327 LYS C CE 1 ATOM 5206 N NZ . LYS B 1 269 ? 16.389 -123.017 36.771 1.00 46.05 ? 327 LYS C NZ 1 ATOM 5207 N N . THR B 1 270 ? 19.674 -116.821 39.912 1.00 12.41 ? 328 THR C N 1 ATOM 5208 C CA . THR B 1 270 ? 19.592 -115.358 39.979 1.00 15.50 ? 328 THR C CA 1 ATOM 5209 C C . THR B 1 270 ? 20.648 -114.669 39.110 1.00 16.24 ? 328 THR C C 1 ATOM 5210 O O . THR B 1 270 ? 20.487 -113.508 38.743 1.00 18.23 ? 328 THR C O 1 ATOM 5211 C CB . THR B 1 270 ? 19.741 -114.826 41.419 1.00 24.72 ? 328 THR C CB 1 ATOM 5212 O OG1 . THR B 1 270 ? 21.048 -115.132 41.923 1.00 33.58 ? 328 THR C OG1 1 ATOM 5213 C CG2 . THR B 1 270 ? 18.684 -115.427 42.325 1.00 18.74 ? 328 THR C CG2 1 ATOM 5214 N N . PHE B 1 271 ? 21.724 -115.384 38.789 1.00 16.00 ? 329 PHE C N 1 ATOM 5215 C CA . PHE B 1 271 ? 22.773 -114.856 37.920 1.00 15.58 ? 329 PHE C CA 1 ATOM 5216 C C . PHE B 1 271 ? 22.629 -115.322 36.473 1.00 22.96 ? 329 PHE C C 1 ATOM 5217 O O . PHE B 1 271 ? 22.915 -114.565 35.544 1.00 17.46 ? 329 PHE C O 1 ATOM 5218 C CB . PHE B 1 271 ? 24.154 -115.265 38.442 1.00 17.43 ? 329 PHE C CB 1 ATOM 5219 C CG . PHE B 1 271 ? 25.289 -114.853 37.545 1.00 14.00 ? 329 PHE C CG 1 ATOM 5220 C CD1 . PHE B 1 271 ? 25.738 -113.543 37.531 1.00 19.87 ? 329 PHE C CD1 1 ATOM 5221 C CD2 . PHE B 1 271 ? 25.911 -115.777 36.721 1.00 15.78 ? 329 PHE C CD2 1 ATOM 5222 C CE1 . PHE B 1 271 ? 26.782 -113.162 36.714 1.00 14.88 ? 329 PHE C CE1 1 ATOM 5223 C CE2 . PHE B 1 271 ? 26.957 -115.403 35.900 1.00 15.85 ? 329 PHE C CE2 1 ATOM 5224 C CZ . PHE B 1 271 ? 27.392 -114.092 35.895 1.00 19.91 ? 329 PHE C CZ 1 ATOM 5225 N N . GLU B 1 272 ? 22.204 -116.566 36.277 1.00 20.31 ? 330 GLU C N 1 ATOM 5226 C CA . GLU B 1 272 ? 22.187 -117.140 34.932 1.00 22.14 ? 330 GLU C CA 1 ATOM 5227 C C . GLU B 1 272 ? 20.861 -117.057 34.160 1.00 21.00 ? 330 GLU C C 1 ATOM 5228 O O . GLU B 1 272 ? 20.828 -117.408 32.983 1.00 25.70 ? 330 GLU C O 1 ATOM 5229 C CB . GLU B 1 272 ? 22.630 -118.601 35.008 1.00 19.26 ? 330 GLU C CB 1 ATOM 5230 C CG . GLU B 1 272 ? 24.133 -118.753 35.192 1.00 32.54 ? 330 GLU C CG 1 ATOM 5231 C CD . GLU B 1 272 ? 24.586 -120.196 35.187 1.00 35.30 ? 330 GLU C CD 1 ATOM 5232 O OE1 . GLU B 1 272 ? 25.793 -120.439 35.403 1.00 38.60 ? 330 GLU C OE1 1 ATOM 5233 O OE2 . GLU B 1 272 ? 23.740 -121.088 34.965 1.00 48.01 ? 330 GLU C OE2 1 ATOM 5234 N N . ASN B 1 273 ? 19.781 -116.589 34.782 1.00 25.24 ? 331 ASN C N 1 ATOM 5235 C CA . ASN B 1 273 ? 18.501 -116.512 34.069 1.00 21.85 ? 331 ASN C CA 1 ATOM 5236 C C . ASN B 1 273 ? 18.557 -115.458 32.962 1.00 27.96 ? 331 ASN C C 1 ATOM 5237 O O . ASN B 1 273 ? 19.364 -114.531 33.018 1.00 28.27 ? 331 ASN C O 1 ATOM 5238 C CB . ASN B 1 273 ? 17.341 -116.221 35.033 1.00 12.98 ? 331 ASN C CB 1 ATOM 5239 C CG . ASN B 1 273 ? 17.263 -114.763 35.449 1.00 18.28 ? 331 ASN C CG 1 ATOM 5240 O OD1 . ASN B 1 273 ? 16.725 -113.928 34.723 1.00 17.78 ? 331 ASN C OD1 1 ATOM 5241 N ND2 . ASN B 1 273 ? 17.775 -114.456 36.636 1.00 18.33 ? 331 ASN C ND2 1 ATOM 5242 N N . ASP B 1 274 ? 17.694 -115.608 31.959 1.00 20.40 ? 332 ASP C N 1 ATOM 5243 C CA . ASP B 1 274 ? 17.798 -114.828 30.724 1.00 26.78 ? 332 ASP C CA 1 ATOM 5244 C C . ASP B 1 274 ? 17.479 -113.342 30.892 1.00 22.70 ? 332 ASP C C 1 ATOM 5245 O O . ASP B 1 274 ? 17.691 -112.557 29.968 1.00 26.52 ? 332 ASP C O 1 ATOM 5246 C CB . ASP B 1 274 ? 16.881 -115.424 29.644 1.00 31.73 ? 332 ASP C CB 1 ATOM 5247 C CG . ASP B 1 274 ? 15.409 -115.438 30.048 1.00 88.99 ? 332 ASP C CG 1 ATOM 5248 O OD1 . ASP B 1 274 ? 15.029 -114.750 31.019 1.00 52.44 ? 332 ASP C OD1 1 ATOM 5249 O OD2 . ASP B 1 274 ? 14.622 -116.141 29.376 1.00 69.90 ? 332 ASP C OD2 1 ATOM 5250 N N . GLY B 1 275 ? 16.973 -112.960 32.061 1.00 16.11 ? 333 GLY C N 1 ATOM 5251 C CA . GLY B 1 275 ? 16.573 -111.584 32.307 1.00 19.40 ? 333 GLY C CA 1 ATOM 5252 C C . GLY B 1 275 ? 17.588 -110.750 33.075 1.00 17.82 ? 333 GLY C C 1 ATOM 5253 O O . GLY B 1 275 ? 17.388 -109.553 33.272 1.00 19.68 ? 333 GLY C O 1 ATOM 5254 N N . VAL B 1 276 ? 18.680 -111.373 33.507 1.00 18.45 ? 334 VAL C N 1 ATOM 5255 C CA . VAL B 1 276 ? 19.690 -110.684 34.308 1.00 18.96 ? 334 VAL C CA 1 ATOM 5256 C C . VAL B 1 276 ? 20.334 -109.542 33.530 1.00 23.40 ? 334 VAL C C 1 ATOM 5257 O O . VAL B 1 276 ? 20.567 -109.657 32.328 1.00 21.29 ? 334 VAL C O 1 ATOM 5258 C CB . VAL B 1 276 ? 20.780 -111.658 34.773 1.00 18.95 ? 334 VAL C CB 1 ATOM 5259 C CG1 . VAL B 1 276 ? 21.877 -110.929 35.537 1.00 27.83 ? 334 VAL C CG1 1 ATOM 5260 C CG2 . VAL B 1 276 ? 20.168 -112.735 35.646 1.00 27.18 ? 334 VAL C CG2 1 ATOM 5261 N N . ALA B 1 277 ? 20.620 -108.445 34.226 1.00 21.47 ? 335 ALA C N 1 ATOM 5262 C CA . ALA B 1 277 ? 21.252 -107.282 33.609 1.00 20.56 ? 335 ALA C CA 1 ATOM 5263 C C . ALA B 1 277 ? 22.490 -107.681 32.812 1.00 17.28 ? 335 ALA C C 1 ATOM 5264 O O . ALA B 1 277 ? 23.420 -108.282 33.351 1.00 20.75 ? 335 ALA C O 1 ATOM 5265 C CB . ALA B 1 277 ? 21.617 -106.263 34.668 1.00 23.13 ? 335 ALA C CB 1 ATOM 5266 N N . SER B 1 278 ? 22.487 -107.348 31.525 1.00 22.41 ? 336 SER C N 1 ATOM 5267 C CA . SER B 1 278 ? 23.575 -107.721 30.628 1.00 20.47 ? 336 SER C CA 1 ATOM 5268 C C . SER B 1 278 ? 23.803 -106.650 29.568 1.00 23.08 ? 336 SER C C 1 ATOM 5269 O O . SER B 1 278 ? 22.854 -106.057 29.058 1.00 17.26 ? 336 SER C O 1 ATOM 5270 C CB . SER B 1 278 ? 23.279 -109.063 29.958 1.00 22.30 ? 336 SER C CB 1 ATOM 5271 O OG . SER B 1 278 ? 24.291 -109.399 29.024 1.00 25.32 ? 336 SER C OG 1 ATOM 5272 N N . ASP B 1 279 ? 25.070 -106.415 29.243 1.00 21.90 ? 337 ASP C N 1 ATOM 5273 C CA . ASP B 1 279 ? 25.444 -105.409 28.255 1.00 21.77 ? 337 ASP C CA 1 ATOM 5274 C C . ASP B 1 279 ? 25.878 -106.058 26.940 1.00 18.33 ? 337 ASP C C 1 ATOM 5275 O O . ASP B 1 279 ? 26.379 -105.382 26.042 1.00 24.34 ? 337 ASP C O 1 ATOM 5276 C CB . ASP B 1 279 ? 26.564 -104.519 28.804 1.00 24.36 ? 337 ASP C CB 1 ATOM 5277 C CG . ASP B 1 279 ? 26.171 -103.811 30.091 1.00 28.44 ? 337 ASP C CG 1 ATOM 5278 O OD1 . ASP B 1 279 ? 24.959 -103.716 30.378 1.00 27.37 ? 337 ASP C OD1 1 ATOM 5279 O OD2 . ASP B 1 279 ? 27.076 -103.343 30.813 1.00 23.36 ? 337 ASP C OD2 1 ATOM 5280 N N . GLN B 1 280 ? 25.685 -107.370 26.831 1.00 16.92 ? 338 GLN C N 1 ATOM 5281 C CA . GLN B 1 280 ? 26.020 -108.098 25.608 1.00 20.69 ? 338 GLN C CA 1 ATOM 5282 C C . GLN B 1 280 ? 25.151 -107.625 24.442 1.00 25.22 ? 338 GLN C C 1 ATOM 5283 O O . GLN B 1 280 ? 23.968 -107.354 24.633 1.00 22.15 ? 338 GLN C O 1 ATOM 5284 C CB . GLN B 1 280 ? 25.830 -109.602 25.811 1.00 22.55 ? 338 GLN C CB 1 ATOM 5285 C CG . GLN B 1 280 ? 26.340 -110.461 24.660 1.00 24.98 ? 338 GLN C CG 1 ATOM 5286 C CD . GLN B 1 280 ? 27.852 -110.615 24.665 1.00 33.70 ? 338 GLN C CD 1 ATOM 5287 O OE1 . GLN B 1 280 ? 28.537 -110.090 25.543 1.00 25.39 ? 338 GLN C OE1 1 ATOM 5288 N NE2 . GLN B 1 280 ? 28.379 -111.328 23.675 1.00 26.57 ? 338 GLN C NE2 1 ATOM 5289 N N . PRO B 1 281 ? 25.731 -107.526 23.230 1.00 23.71 ? 339 PRO C N 1 ATOM 5290 C CA . PRO B 1 281 ? 24.920 -107.158 22.061 1.00 36.82 ? 339 PRO C CA 1 ATOM 5291 C C . PRO B 1 281 ? 23.811 -108.164 21.768 1.00 26.37 ? 339 PRO C C 1 ATOM 5292 O O . PRO B 1 281 ? 24.066 -109.364 21.879 1.00 28.94 ? 339 PRO C O 1 ATOM 5293 C CB . PRO B 1 281 ? 25.940 -107.131 20.914 1.00 34.29 ? 339 PRO C CB 1 ATOM 5294 C CG . PRO B 1 281 ? 27.121 -107.890 21.410 1.00 36.92 ? 339 PRO C CG 1 ATOM 5295 C CD . PRO B 1 281 ? 27.156 -107.653 22.880 1.00 27.36 ? 339 PRO C CD 1 ATOM 5296 N N . ASP B 1 289 ? 25.501 -102.765 17.898 1.00 50.05 ? 360 ASP C N 1 ATOM 5297 C CA . ASP B 1 289 ? 24.629 -102.791 19.066 1.00 46.47 ? 360 ASP C CA 1 ATOM 5298 C C . ASP B 1 289 ? 25.460 -102.875 20.342 1.00 45.82 ? 360 ASP C C 1 ATOM 5299 O O . ASP B 1 289 ? 26.244 -103.806 20.519 1.00 35.64 ? 360 ASP C O 1 ATOM 5300 C CB . ASP B 1 289 ? 23.660 -103.974 18.986 1.00 48.81 ? 360 ASP C CB 1 ATOM 5301 C CG . ASP B 1 289 ? 22.554 -103.899 20.025 1.00 53.07 ? 360 ASP C CG 1 ATOM 5302 O OD1 . ASP B 1 289 ? 21.997 -102.800 20.229 1.00 55.18 ? 360 ASP C OD1 1 ATOM 5303 O OD2 . ASP B 1 289 ? 22.244 -104.943 20.637 1.00 53.17 ? 360 ASP C OD2 1 ATOM 5304 N N . GLN B 1 290 ? 25.291 -101.894 21.222 1.00 31.72 ? 361 GLN C N 1 ATOM 5305 C CA . GLN B 1 290 ? 26.051 -101.837 22.466 1.00 35.09 ? 361 GLN C CA 1 ATOM 5306 C C . GLN B 1 290 ? 25.145 -101.421 23.619 1.00 33.87 ? 361 GLN C C 1 ATOM 5307 O O . GLN B 1 290 ? 25.235 -100.298 24.116 1.00 32.14 ? 361 GLN C O 1 ATOM 5308 C CB . GLN B 1 290 ? 27.226 -100.870 22.325 1.00 29.50 ? 361 GLN C CB 1 ATOM 5309 C CG . GLN B 1 290 ? 28.113 -101.171 21.126 1.00 36.99 ? 361 GLN C CG 1 ATOM 5310 C CD . GLN B 1 290 ? 29.443 -100.450 21.186 1.00 41.13 ? 361 GLN C CD 1 ATOM 5311 O OE1 . GLN B 1 290 ? 29.590 -99.455 21.898 1.00 46.19 ? 361 GLN C OE1 1 ATOM 5312 N NE2 . GLN B 1 290 ? 30.423 -100.951 20.442 1.00 30.75 ? 361 GLN C NE2 1 ATOM 5313 N N . PRO B 1 291 ? 24.263 -102.335 24.049 1.00 28.90 ? 362 PRO C N 1 ATOM 5314 C CA . PRO B 1 291 ? 23.283 -102.017 25.090 1.00 27.95 ? 362 PRO C CA 1 ATOM 5315 C C . PRO B 1 291 ? 23.921 -101.760 26.452 1.00 27.75 ? 362 PRO C C 1 ATOM 5316 O O . PRO B 1 291 ? 24.897 -102.418 26.819 1.00 23.49 ? 362 PRO C O 1 ATOM 5317 C CB . PRO B 1 291 ? 22.396 -103.265 25.127 1.00 25.11 ? 362 PRO C CB 1 ATOM 5318 C CG . PRO B 1 291 ? 23.244 -104.352 24.604 1.00 33.09 ? 362 PRO C CG 1 ATOM 5319 C CD . PRO B 1 291 ? 24.142 -103.729 23.587 1.00 26.83 ? 362 PRO C CD 1 ATOM 5320 N N . HIS B 1 292 ? 23.367 -100.792 27.176 1.00 28.42 ? 363 HIS C N 1 ATOM 5321 C CA . HIS B 1 292 ? 23.763 -100.510 28.550 1.00 31.57 ? 363 HIS C CA 1 ATOM 5322 C C . HIS B 1 292 ? 22.584 -100.784 29.476 1.00 26.65 ? 363 HIS C C 1 ATOM 5323 O O . HIS B 1 292 ? 21.645 -99.994 29.546 1.00 24.07 ? 363 HIS C O 1 ATOM 5324 C CB . HIS B 1 292 ? 24.231 -99.060 28.698 1.00 29.39 ? 363 HIS C CB 1 ATOM 5325 C CG . HIS B 1 292 ? 25.503 -98.755 27.969 1.00 37.65 ? 363 HIS C CG 1 ATOM 5326 N ND1 . HIS B 1 292 ? 25.937 -97.467 27.739 1.00 46.17 ? 363 HIS C ND1 1 ATOM 5327 C CD2 . HIS B 1 292 ? 26.439 -99.569 27.425 1.00 38.90 ? 363 HIS C CD2 1 ATOM 5328 C CE1 . HIS B 1 292 ? 27.082 -97.500 27.081 1.00 44.34 ? 363 HIS C CE1 1 ATOM 5329 N NE2 . HIS B 1 292 ? 27.409 -98.764 26.878 1.00 41.37 ? 363 HIS C NE2 1 ATOM 5330 N N . SER B 1 293 ? 22.633 -101.913 30.177 1.00 26.38 ? 364 SER C N 1 ATOM 5331 C CA . SER B 1 293 ? 21.566 -102.282 31.100 1.00 28.61 ? 364 SER C CA 1 ATOM 5332 C C . SER B 1 293 ? 21.439 -101.268 32.235 1.00 28.09 ? 364 SER C C 1 ATOM 5333 O O . SER B 1 293 ? 20.335 -100.969 32.690 1.00 28.17 ? 364 SER C O 1 ATOM 5334 C CB . SER B 1 293 ? 21.819 -103.676 31.677 1.00 30.02 ? 364 SER C CB 1 ATOM 5335 O OG . SER B 1 293 ? 22.982 -103.686 32.487 1.00 26.32 ? 364 SER C OG 1 ATOM 5336 N N . GLY B 1 294 ? 22.571 -100.739 32.688 1.00 29.45 ? 365 GLY C N 1 ATOM 5337 C CA . GLY B 1 294 ? 22.580 -99.814 33.808 1.00 25.03 ? 365 GLY C CA 1 ATOM 5338 C C . GLY B 1 294 ? 22.224 -100.499 35.116 1.00 23.15 ? 365 GLY C C 1 ATOM 5339 O O . GLY B 1 294 ? 21.869 -99.840 36.094 1.00 26.94 ? 365 GLY C O 1 ATOM 5340 N N . GLY B 1 295 ? 22.319 -101.827 35.130 1.00 23.20 ? 366 GLY C N 1 ATOM 5341 C CA . GLY B 1 295 ? 22.013 -102.612 36.314 1.00 31.18 ? 366 GLY C CA 1 ATOM 5342 C C . GLY B 1 295 ? 20.573 -103.085 36.390 1.00 24.27 ? 366 GLY C C 1 ATOM 5343 O O . GLY B 1 295 ? 20.204 -103.804 37.318 1.00 25.11 ? 366 GLY C O 1 ATOM 5344 N N . VAL B 1 296 ? 19.759 -102.689 35.417 1.00 23.36 ? 367 VAL C N 1 ATOM 5345 C CA . VAL B 1 296 ? 18.353 -103.081 35.383 1.00 20.98 ? 367 VAL C CA 1 ATOM 5346 C C . VAL B 1 296 ? 18.196 -104.508 34.854 1.00 22.27 ? 367 VAL C C 1 ATOM 5347 O O . VAL B 1 296 ? 18.783 -104.858 33.831 1.00 25.05 ? 367 VAL C O 1 ATOM 5348 C CB . VAL B 1 296 ? 17.530 -102.122 34.500 1.00 30.00 ? 367 VAL C CB 1 ATOM 5349 C CG1 . VAL B 1 296 ? 16.075 -102.563 34.432 1.00 31.34 ? 367 VAL C CG1 1 ATOM 5350 C CG2 . VAL B 1 296 ? 17.626 -100.696 35.028 1.00 23.50 ? 367 VAL C CG2 1 ATOM 5351 N N . GLY B 1 297 ? 17.403 -105.325 35.544 1.00 23.29 ? 368 GLY C N 1 ATOM 5352 C CA . GLY B 1 297 ? 17.134 -106.679 35.085 1.00 19.91 ? 368 GLY C CA 1 ATOM 5353 C C . GLY B 1 297 ? 16.628 -107.610 36.172 1.00 21.98 ? 368 GLY C C 1 ATOM 5354 O O . GLY B 1 297 ? 16.524 -107.220 37.334 1.00 18.75 ? 368 GLY C O 1 ATOM 5355 N N . ARG B 1 298 ? 16.311 -108.846 35.787 1.00 22.63 ? 369 ARG C N 1 ATOM 5356 C CA A ARG B 1 298 ? 15.821 -109.848 36.732 0.58 20.16 ? 369 ARG C CA 1 ATOM 5357 C CA B ARG B 1 298 ? 15.815 -109.844 36.726 0.42 20.88 ? 369 ARG C CA 1 ATOM 5358 C C . ARG B 1 298 ? 16.968 -110.342 37.600 1.00 18.47 ? 369 ARG C C 1 ATOM 5359 O O . ARG B 1 298 ? 17.416 -111.485 37.481 1.00 17.26 ? 369 ARG C O 1 ATOM 5360 C CB A ARG B 1 298 ? 15.164 -111.022 35.998 0.58 20.55 ? 369 ARG C CB 1 ATOM 5361 C CB B ARG B 1 298 ? 15.142 -110.993 35.965 0.42 20.50 ? 369 ARG C CB 1 ATOM 5362 C CG A ARG B 1 298 ? 14.438 -111.994 36.924 0.58 20.28 ? 369 ARG C CG 1 ATOM 5363 C CG B ARG B 1 298 ? 13.984 -111.634 36.709 0.42 19.86 ? 369 ARG C CG 1 ATOM 5364 C CD A ARG B 1 298 ? 13.873 -113.194 36.176 0.58 21.66 ? 369 ARG C CD 1 ATOM 5365 C CD B ARG B 1 298 ? 13.212 -112.596 35.815 0.42 22.09 ? 369 ARG C CD 1 ATOM 5366 N NE A ARG B 1 298 ? 12.920 -112.808 35.136 0.58 19.04 ? 369 ARG C NE 1 ATOM 5367 N NE B ARG B 1 298 ? 12.365 -111.898 34.848 0.42 21.86 ? 369 ARG C NE 1 ATOM 5368 C CZ A ARG B 1 298 ? 12.976 -113.184 33.858 0.58 18.78 ? 369 ARG C CZ 1 ATOM 5369 C CZ B ARG B 1 298 ? 11.150 -111.425 35.114 0.42 25.67 ? 369 ARG C CZ 1 ATOM 5370 N NH1 A ARG B 1 298 ? 13.943 -113.977 33.409 0.58 17.83 ? 369 ARG C NH1 1 ATOM 5371 N NH1 B ARG B 1 298 ? 10.624 -111.563 36.326 0.42 21.53 ? 369 ARG C NH1 1 ATOM 5372 N NH2 A ARG B 1 298 ? 12.045 -112.759 33.016 0.58 24.16 ? 369 ARG C NH2 1 ATOM 5373 N NH2 B ARG B 1 298 ? 10.456 -110.808 34.168 0.42 23.84 ? 369 ARG C NH2 1 ATOM 5374 N N . ASN B 1 299 ? 17.434 -109.465 38.482 1.00 20.86 ? 370 ASN C N 1 ATOM 5375 C CA . ASN B 1 299 ? 18.621 -109.721 39.279 1.00 19.05 ? 370 ASN C CA 1 ATOM 5376 C C . ASN B 1 299 ? 18.329 -110.282 40.658 1.00 23.00 ? 370 ASN C C 1 ATOM 5377 O O . ASN B 1 299 ? 19.261 -110.673 41.366 1.00 24.62 ? 370 ASN C O 1 ATOM 5378 C CB . ASN B 1 299 ? 19.425 -108.428 39.436 1.00 18.75 ? 370 ASN C CB 1 ATOM 5379 C CG . ASN B 1 299 ? 19.737 -107.769 38.107 1.00 22.06 ? 370 ASN C CG 1 ATOM 5380 O OD1 . ASN B 1 299 ? 19.997 -108.444 37.112 1.00 20.53 ? 370 ASN C OD1 1 ATOM 5381 N ND2 . ASN B 1 299 ? 19.710 -106.442 38.084 1.00 23.70 ? 370 ASN C ND2 1 ATOM 5382 N N . TYR B 1 300 ? 17.057 -110.319 41.050 1.00 23.11 ? 371 TYR C N 1 ATOM 5383 C CA . TYR B 1 300 ? 16.729 -110.645 42.433 1.00 17.80 ? 371 TYR C CA 1 ATOM 5384 C C . TYR B 1 300 ? 15.952 -111.928 42.549 1.00 25.14 ? 371 TYR C C 1 ATOM 5385 O O . TYR B 1 300 ? 15.077 -112.205 41.737 1.00 24.11 ? 371 TYR C O 1 ATOM 5386 C CB . TYR B 1 300 ? 15.947 -109.495 43.047 1.00 20.74 ? 371 TYR C CB 1 ATOM 5387 C CG . TYR B 1 300 ? 16.605 -108.183 42.741 1.00 21.26 ? 371 TYR C CG 1 ATOM 5388 C CD1 . TYR B 1 300 ? 17.688 -107.745 43.484 1.00 21.96 ? 371 TYR C CD1 1 ATOM 5389 C CD2 . TYR B 1 300 ? 16.176 -107.402 41.680 1.00 21.20 ? 371 TYR C CD2 1 ATOM 5390 C CE1 . TYR B 1 300 ? 18.309 -106.556 43.198 1.00 22.24 ? 371 TYR C CE1 1 ATOM 5391 C CE2 . TYR B 1 300 ? 16.792 -106.205 41.385 1.00 18.73 ? 371 TYR C CE2 1 ATOM 5392 C CZ . TYR B 1 300 ? 17.862 -105.787 42.150 1.00 23.28 ? 371 TYR C CZ 1 ATOM 5393 O OH . TYR B 1 300 ? 18.490 -104.596 41.870 1.00 26.56 ? 371 TYR C OH 1 ATOM 5394 N N . GLY B 1 301 ? 16.283 -112.730 43.549 1.00 23.58 ? 372 GLY C N 1 ATOM 5395 C CA . GLY B 1 301 ? 15.510 -113.931 43.760 1.00 22.60 ? 372 GLY C CA 1 ATOM 5396 C C . GLY B 1 301 ? 15.579 -114.484 45.158 1.00 29.43 ? 372 GLY C C 1 ATOM 5397 O O . GLY B 1 301 ? 16.339 -113.999 45.995 1.00 24.06 ? 372 GLY C O 1 ATOM 5398 N N . PHE B 1 302 ? 14.763 -115.496 45.427 1.00 19.70 ? 373 PHE C N 1 ATOM 5399 C CA . PHE B 1 302 ? 14.946 -116.243 46.662 1.00 22.96 ? 373 PHE C CA 1 ATOM 5400 C C . PHE B 1 302 ? 14.525 -117.693 46.547 1.00 21.09 ? 373 PHE C C 1 ATOM 5401 O O . PHE B 1 302 ? 13.620 -118.054 45.779 1.00 21.40 ? 373 PHE C O 1 ATOM 5402 C CB . PHE B 1 302 ? 14.205 -115.582 47.838 1.00 21.27 ? 373 PHE C CB 1 ATOM 5403 C CG . PHE B 1 302 ? 12.735 -115.375 47.616 1.00 20.50 ? 373 PHE C CG 1 ATOM 5404 C CD1 . PHE B 1 302 ? 11.836 -116.418 47.771 1.00 20.99 ? 373 PHE C CD1 1 ATOM 5405 C CD2 . PHE B 1 302 ? 12.248 -114.120 47.295 1.00 21.44 ? 373 PHE C CD2 1 ATOM 5406 C CE1 . PHE B 1 302 ? 10.481 -116.215 47.581 1.00 19.77 ? 373 PHE C CE1 1 ATOM 5407 C CE2 . PHE B 1 302 ? 10.898 -113.912 47.105 1.00 21.93 ? 373 PHE C CE2 1 ATOM 5408 C CZ . PHE B 1 302 ? 10.013 -114.960 47.248 1.00 21.27 ? 373 PHE C CZ 1 ATOM 5409 N N . TYR B 1 303 ? 15.236 -118.517 47.307 1.00 14.54 ? 374 TYR C N 1 ATOM 5410 C CA . TYR B 1 303 ? 14.875 -119.902 47.506 1.00 17.54 ? 374 TYR C CA 1 ATOM 5411 C C . TYR B 1 303 ? 13.837 -119.950 48.609 1.00 27.65 ? 374 TYR C C 1 ATOM 5412 O O . TYR B 1 303 ? 13.963 -119.240 49.620 1.00 22.33 ? 374 TYR C O 1 ATOM 5413 C CB . TYR B 1 303 ? 16.098 -120.746 47.877 1.00 15.48 ? 374 TYR C CB 1 ATOM 5414 C CG . TYR B 1 303 ? 15.765 -122.142 48.364 1.00 19.26 ? 374 TYR C CG 1 ATOM 5415 C CD1 . TYR B 1 303 ? 15.667 -123.206 47.475 1.00 21.47 ? 374 TYR C CD1 1 ATOM 5416 C CD2 . TYR B 1 303 ? 15.550 -122.394 49.712 1.00 27.38 ? 374 TYR C CD2 1 ATOM 5417 C CE1 . TYR B 1 303 ? 15.365 -124.481 47.916 1.00 26.54 ? 374 TYR C CE1 1 ATOM 5418 C CE2 . TYR B 1 303 ? 15.245 -123.667 50.163 1.00 24.44 ? 374 TYR C CE2 1 ATOM 5419 C CZ . TYR B 1 303 ? 15.153 -124.706 49.259 1.00 31.60 ? 374 TYR C CZ 1 ATOM 5420 O OH . TYR B 1 303 ? 14.853 -125.977 49.691 1.00 36.47 ? 374 TYR C OH 1 ATOM 5421 N N . TYR B 1 304 ? 12.804 -120.760 48.394 1.00 20.04 ? 375 TYR C N 1 ATOM 5422 C CA . TYR B 1 304 ? 11.826 -121.051 49.437 1.00 23.08 ? 375 TYR C CA 1 ATOM 5423 C C . TYR B 1 304 ? 11.293 -122.474 49.302 1.00 27.71 ? 375 TYR C C 1 ATOM 5424 O O . TYR B 1 304 ? 11.426 -123.104 48.252 1.00 30.27 ? 375 TYR C O 1 ATOM 5425 C CB . TYR B 1 304 ? 10.667 -120.049 49.398 1.00 22.89 ? 375 TYR C CB 1 ATOM 5426 C CG . TYR B 1 304 ? 9.769 -120.157 48.186 1.00 30.52 ? 375 TYR C CG 1 ATOM 5427 C CD1 . TYR B 1 304 ? 10.118 -119.558 46.984 1.00 25.10 ? 375 TYR C CD1 1 ATOM 5428 C CD2 . TYR B 1 304 ? 8.560 -120.840 48.252 1.00 31.81 ? 375 TYR C CD2 1 ATOM 5429 C CE1 . TYR B 1 304 ? 9.299 -119.646 45.877 1.00 29.19 ? 375 TYR C CE1 1 ATOM 5430 C CE2 . TYR B 1 304 ? 7.732 -120.932 47.149 1.00 33.79 ? 375 TYR C CE2 1 ATOM 5431 C CZ . TYR B 1 304 ? 8.107 -120.332 45.964 1.00 37.55 ? 375 TYR C CZ 1 ATOM 5432 O OH . TYR B 1 304 ? 7.293 -120.416 44.858 1.00 28.41 ? 375 TYR C OH 1 ATOM 5433 N N . VAL B 1 305 ? 10.707 -122.974 50.384 1.00 30.93 ? 376 VAL C N 1 ATOM 5434 C CA . VAL B 1 305 ? 10.084 -124.293 50.401 1.00 30.44 ? 376 VAL C CA 1 ATOM 5435 C C . VAL B 1 305 ? 8.569 -124.119 50.372 1.00 30.13 ? 376 VAL C C 1 ATOM 5436 O O . VAL B 1 305 ? 7.995 -123.491 51.262 1.00 35.88 ? 376 VAL C O 1 ATOM 5437 C CB . VAL B 1 305 ? 10.508 -125.101 51.646 1.00 38.96 ? 376 VAL C CB 1 ATOM 5438 C CG1 . VAL B 1 305 ? 9.755 -126.424 51.727 1.00 42.49 ? 376 VAL C CG1 1 ATOM 5439 C CG2 . VAL B 1 305 ? 12.013 -125.347 51.627 1.00 35.27 ? 376 VAL C CG2 1 ATOM 5440 N N . ASP B 1 306 ? 7.924 -124.670 49.346 1.00 32.24 ? 377 ASP C N 1 ATOM 5441 C CA . ASP B 1 306 ? 6.483 -124.501 49.186 1.00 37.07 ? 377 ASP C CA 1 ATOM 5442 C C . ASP B 1 306 ? 5.721 -125.346 50.204 1.00 38.28 ? 377 ASP C C 1 ATOM 5443 O O . ASP B 1 306 ? 6.317 -126.112 50.960 1.00 38.04 ? 377 ASP C O 1 ATOM 5444 C CB . ASP B 1 306 ? 6.041 -124.853 47.754 1.00 41.99 ? 377 ASP C CB 1 ATOM 5445 C CG . ASP B 1 306 ? 6.406 -126.275 47.342 1.00 43.61 ? 377 ASP C CG 1 ATOM 5446 O OD1 . ASP B 1 306 ? 6.611 -127.140 48.219 1.00 51.96 ? 377 ASP C OD1 1 ATOM 5447 O OD2 . ASP B 1 306 ? 6.476 -126.530 46.121 1.00 49.01 ? 377 ASP C OD2 1 ATOM 5448 N N . THR B 1 307 ? 4.403 -125.272 50.163 1.00 54.43 ? 378 THR C N 1 ATOM 5449 C CA . THR B 1 307 ? 3.551 -126.021 51.083 1.00 61.68 ? 378 THR C CA 1 ATOM 5450 C C . THR B 1 307 ? 3.787 -127.514 50.955 1.00 51.54 ? 378 THR C C 1 ATOM 5451 O O . THR B 1 307 ? 3.658 -128.249 51.906 1.00 56.84 ? 378 THR C O 1 ATOM 5452 C CB . THR B 1 307 ? 2.074 -125.698 50.873 1.00 55.97 ? 378 THR C CB 1 ATOM 5453 O OG1 . THR B 1 307 ? 1.614 -126.321 49.672 1.00 76.15 ? 378 THR C OG1 1 ATOM 5454 C CG2 . THR B 1 307 ? 1.886 -124.214 50.761 1.00 48.13 ? 378 THR C CG2 1 ATOM 5455 N N . THR B 1 308 ? 4.113 -127.948 49.758 1.00 43.86 ? 379 THR C N 1 ATOM 5456 C CA . THR B 1 308 ? 4.408 -129.334 49.476 1.00 43.63 ? 379 THR C CA 1 ATOM 5457 C C . THR B 1 308 ? 5.765 -129.813 49.996 1.00 46.23 ? 379 THR C C 1 ATOM 5458 O O . THR B 1 308 ? 6.014 -131.002 50.006 1.00 50.88 ? 379 THR C O 1 ATOM 5459 C CB . THR B 1 308 ? 4.281 -129.597 47.962 1.00 58.85 ? 379 THR C CB 1 ATOM 5460 O OG1 . THR B 1 308 ? 2.899 -129.564 47.608 1.00 62.38 ? 379 THR C OG1 1 ATOM 5461 C CG2 . THR B 1 308 ? 4.846 -130.937 47.558 1.00 53.42 ? 379 THR C CG2 1 ATOM 5462 N N . GLY B 1 309 ? 6.648 -128.909 50.400 1.00 46.76 ? 380 GLY C N 1 ATOM 5463 C CA . GLY B 1 309 ? 7.957 -129.326 50.854 1.00 36.60 ? 380 GLY C CA 1 ATOM 5464 C C . GLY B 1 309 ? 9.016 -129.452 49.772 1.00 40.83 ? 380 GLY C C 1 ATOM 5465 O O . GLY B 1 309 ? 10.060 -130.020 49.983 1.00 40.18 ? 380 GLY C O 1 ATOM 5466 N N . GLU B 1 310 ? 8.729 -128.925 48.598 1.00 35.16 ? 381 GLU C N 1 ATOM 5467 C CA . GLU B 1 310 ? 9.656 -128.954 47.471 1.00 51.32 ? 381 GLU C CA 1 ATOM 5468 C C . GLU B 1 310 ? 10.335 -127.602 47.283 1.00 28.90 ? 381 GLU C C 1 ATOM 5469 O O . GLU B 1 310 ? 9.731 -126.555 47.515 1.00 29.09 ? 381 GLU C O 1 ATOM 5470 C CB . GLU B 1 310 ? 8.925 -129.358 46.190 1.00 48.44 ? 381 GLU C CB 1 ATOM 5471 C CG . GLU B 1 310 ? 8.766 -130.862 46.033 1.00 71.42 ? 381 GLU C CG 1 ATOM 5472 C CD . GLU B 1 310 ? 7.870 -131.243 44.871 1.00 109.34 ? 381 GLU C CD 1 ATOM 5473 O OE1 . GLU B 1 310 ? 7.651 -132.455 44.663 1.00 105.82 ? 381 GLU C OE1 1 ATOM 5474 O OE2 . GLU B 1 310 ? 7.384 -130.333 44.166 1.00 102.08 ? 381 GLU C OE2 1 ATOM 5475 N N . GLY B 1 311 ? 11.593 -127.635 46.856 1.00 27.73 ? 382 GLY C N 1 ATOM 5476 C CA . GLY B 1 311 ? 12.369 -126.423 46.675 1.00 32.67 ? 382 GLY C CA 1 ATOM 5477 C C . GLY B 1 311 ? 11.903 -125.597 45.491 1.00 24.03 ? 382 GLY C C 1 ATOM 5478 O O . GLY B 1 311 ? 11.737 -126.115 44.386 1.00 28.31 ? 382 GLY C O 1 ATOM 5479 N N . LYS B 1 312 ? 11.695 -124.306 45.728 1.00 23.37 ? 383 LYS C N 1 ATOM 5480 C CA . LYS B 1 312 ? 11.304 -123.379 44.678 1.00 20.83 ? 383 LYS C CA 1 ATOM 5481 C C . LYS B 1 312 ? 12.204 -122.151 44.666 1.00 29.14 ? 383 LYS C C 1 ATOM 5482 O O . LYS B 1 312 ? 12.724 -121.726 45.705 1.00 22.62 ? 383 LYS C O 1 ATOM 5483 C CB . LYS B 1 312 ? 9.846 -122.954 44.850 1.00 29.06 ? 383 LYS C CB 1 ATOM 5484 C CG . LYS B 1 312 ? 8.839 -124.072 44.611 1.00 34.66 ? 383 LYS C CG 1 ATOM 5485 C CD . LYS B 1 312 ? 8.697 -124.402 43.129 1.00 33.34 ? 383 LYS C CD 1 ATOM 5486 C CE . LYS B 1 312 ? 7.776 -125.594 42.902 1.00 39.71 ? 383 LYS C CE 1 ATOM 5487 N NZ . LYS B 1 312 ? 6.521 -125.498 43.696 1.00 44.37 ? 383 LYS C NZ 1 ATOM 5488 N N . CYS B 1 313 ? 12.381 -121.599 43.470 1.00 22.35 ? 384 CYS C N 1 ATOM 5489 C CA . CYS B 1 313 ? 13.151 -120.382 43.270 1.00 19.19 ? 384 CYS C CA 1 ATOM 5490 C C . CYS B 1 313 ? 12.276 -119.316 42.630 1.00 22.20 ? 384 CYS C C 1 ATOM 5491 O O . CYS B 1 313 ? 11.710 -119.530 41.551 1.00 25.81 ? 384 CYS C O 1 ATOM 5492 C CB . CYS B 1 313 ? 14.375 -120.654 42.395 1.00 22.52 ? 384 CYS C CB 1 ATOM 5493 S SG . CYS B 1 313 ? 15.509 -119.250 42.259 1.00 32.75 ? 384 CYS C SG 1 ATOM 5494 N N . ALA B 1 314 ? 12.159 -118.177 43.307 1.00 20.29 ? 385 ALA C N 1 ATOM 5495 C CA . ALA B 1 314 ? 11.394 -117.048 42.788 1.00 17.49 ? 385 ALA C CA 1 ATOM 5496 C C . ALA B 1 314 ? 12.350 -115.967 42.305 1.00 27.28 ? 385 ALA C C 1 ATOM 5497 O O . ALA B 1 314 ? 13.260 -115.570 43.039 1.00 23.23 ? 385 ALA C O 1 ATOM 5498 C CB . ALA B 1 314 ? 10.454 -116.498 43.848 1.00 20.88 ? 385 ALA C CB 1 ATOM 5499 N N . LEU B 1 315 ? 12.129 -115.504 41.073 1.00 22.67 ? 386 LEU C N 1 ATOM 5500 C CA . LEU B 1 315 ? 12.999 -114.530 40.412 1.00 19.19 ? 386 LEU C CA 1 ATOM 5501 C C . LEU B 1 315 ? 12.225 -113.296 39.947 1.00 24.43 ? 386 LEU C C 1 ATOM 5502 O O . LEU B 1 315 ? 11.131 -113.406 39.383 1.00 25.44 ? 386 LEU C O 1 ATOM 5503 C CB . LEU B 1 315 ? 13.702 -115.169 39.212 1.00 22.52 ? 386 LEU C CB 1 ATOM 5504 C CG . LEU B 1 315 ? 14.553 -116.409 39.490 1.00 24.66 ? 386 LEU C CG 1 ATOM 5505 C CD1 . LEU B 1 315 ? 14.843 -117.154 38.198 1.00 26.11 ? 386 LEU C CD1 1 ATOM 5506 C CD2 . LEU B 1 315 ? 15.849 -116.023 40.182 1.00 25.65 ? 386 LEU C CD2 1 ATOM 5507 N N . SER B 1 316 ? 12.823 -112.127 40.168 1.00 17.35 ? 387 SER C N 1 ATOM 5508 C CA . SER B 1 316 ? 12.197 -110.846 39.863 1.00 14.17 ? 387 SER C CA 1 ATOM 5509 C C . SER B 1 316 ? 13.224 -109.774 39.483 1.00 21.68 ? 387 SER C C 1 ATOM 5510 O O . SER B 1 316 ? 14.412 -109.850 39.854 1.00 20.48 ? 387 SER C O 1 ATOM 5511 C CB . SER B 1 316 ? 11.370 -110.367 41.060 1.00 16.59 ? 387 SER C CB 1 ATOM 5512 O OG . SER B 1 316 ? 10.730 -109.133 40.789 1.00 22.18 ? 387 SER C OG 1 ATOM 5513 N N . ASP B 1 317 ? 12.740 -108.785 38.731 1.00 22.78 ? 388 ASP C N 1 ATOM 5514 C CA . ASP B 1 317 ? 13.509 -107.595 38.374 1.00 25.18 ? 388 ASP C CA 1 ATOM 5515 C C . ASP B 1 317 ? 13.061 -106.393 39.204 1.00 23.25 ? 388 ASP C C 1 ATOM 5516 O O . ASP B 1 317 ? 13.514 -105.270 38.984 1.00 25.96 ? 388 ASP C O 1 ATOM 5517 C CB . ASP B 1 317 ? 13.369 -107.282 36.875 1.00 25.85 ? 388 ASP C CB 1 ATOM 5518 C CG . ASP B 1 317 ? 11.922 -107.057 36.445 1.00 36.49 ? 388 ASP C CG 1 ATOM 5519 O OD1 . ASP B 1 317 ? 11.024 -106.991 37.311 1.00 41.02 ? 388 ASP C OD1 1 ATOM 5520 O OD2 . ASP B 1 317 ? 11.684 -106.937 35.224 1.00 36.49 ? 388 ASP C OD2 1 ATOM 5521 N N . GLN B 1 318 ? 12.162 -106.640 40.151 1.00 24.88 ? 389 GLN C N 1 ATOM 5522 C CA . GLN B 1 318 ? 11.702 -105.607 41.068 1.00 29.51 ? 389 GLN C CA 1 ATOM 5523 C C . GLN B 1 318 ? 12.706 -105.408 42.195 1.00 26.22 ? 389 GLN C C 1 ATOM 5524 O O . GLN B 1 318 ? 12.944 -106.318 42.988 1.00 24.57 ? 389 GLN C O 1 ATOM 5525 C CB . GLN B 1 318 ? 10.335 -105.980 41.644 1.00 31.49 ? 389 GLN C CB 1 ATOM 5526 C CG . GLN B 1 318 ? 9.222 -106.037 40.611 1.00 37.27 ? 389 GLN C CG 1 ATOM 5527 C CD . GLN B 1 318 ? 8.618 -104.676 40.334 1.00 48.66 ? 389 GLN C CD 1 ATOM 5528 O OE1 . GLN B 1 318 ? 8.711 -104.156 39.222 1.00 57.33 ? 389 GLN C OE1 1 ATOM 5529 N NE2 . GLN B 1 318 ? 7.987 -104.094 41.347 1.00 53.06 ? 389 GLN C NE2 1 ATOM 5530 N N . VAL B 1 319 ? 13.298 -104.220 42.263 1.00 23.21 ? 390 VAL C N 1 ATOM 5531 C CA . VAL B 1 319 ? 14.224 -103.905 43.343 1.00 27.02 ? 390 VAL C CA 1 ATOM 5532 C C . VAL B 1 319 ? 13.494 -104.035 44.678 1.00 25.92 ? 390 VAL C C 1 ATOM 5533 O O . VAL B 1 319 ? 12.478 -103.376 44.893 1.00 31.37 ? 390 VAL C O 1 ATOM 5534 C CB . VAL B 1 319 ? 14.808 -102.489 43.199 1.00 27.87 ? 390 VAL C CB 1 ATOM 5535 C CG1 . VAL B 1 319 ? 15.640 -102.120 44.425 1.00 27.23 ? 390 VAL C CG1 1 ATOM 5536 C CG2 . VAL B 1 319 ? 15.653 -102.395 41.935 1.00 31.87 ? 390 VAL C CG2 1 ATOM 5537 N N . PRO B 1 320 ? 13.998 -104.893 45.578 1.00 28.34 ? 391 PRO C N 1 ATOM 5538 C CA . PRO B 1 320 ? 13.287 -105.070 46.848 1.00 26.36 ? 391 PRO C CA 1 ATOM 5539 C C . PRO B 1 320 ? 13.374 -103.833 47.735 1.00 31.46 ? 391 PRO C C 1 ATOM 5540 O O . PRO B 1 320 ? 14.454 -103.254 47.857 1.00 30.92 ? 391 PRO C O 1 ATOM 5541 C CB . PRO B 1 320 ? 14.005 -106.259 47.492 1.00 28.51 ? 391 PRO C CB 1 ATOM 5542 C CG . PRO B 1 320 ? 15.363 -106.258 46.890 1.00 26.65 ? 391 PRO C CG 1 ATOM 5543 C CD . PRO B 1 320 ? 15.209 -105.729 45.500 1.00 23.42 ? 391 PRO C CD 1 ATOM 5544 N N . ASP B 1 321 ? 12.252 -103.428 48.325 1.00 25.59 ? 392 ASP C N 1 ATOM 5545 C CA . ASP B 1 321 ? 12.259 -102.351 49.308 1.00 32.47 ? 392 ASP C CA 1 ATOM 5546 C C . ASP B 1 321 ? 11.592 -102.802 50.604 1.00 33.81 ? 392 ASP C C 1 ATOM 5547 O O . ASP B 1 321 ? 11.389 -101.999 51.516 1.00 32.91 ? 392 ASP C O 1 ATOM 5548 C CB . ASP B 1 321 ? 11.579 -101.090 48.756 1.00 36.49 ? 392 ASP C CB 1 ATOM 5549 C CG . ASP B 1 321 ? 10.119 -101.306 48.395 1.00 42.90 ? 392 ASP C CG 1 ATOM 5550 O OD1 . ASP B 1 321 ? 9.534 -102.338 48.785 1.00 40.58 ? 392 ASP C OD1 1 ATOM 5551 O OD2 . ASP B 1 321 ? 9.547 -100.422 47.722 1.00 44.96 ? 392 ASP C OD2 1 ATOM 5552 N N . CYS B 1 322 ? 11.234 -104.082 50.683 1.00 31.88 ? 393 CYS C N 1 ATOM 5553 C CA . CYS B 1 322 ? 10.868 -104.662 51.970 1.00 28.33 ? 393 CYS C CA 1 ATOM 5554 C C . CYS B 1 322 ? 11.141 -106.161 52.015 1.00 30.91 ? 393 CYS C C 1 ATOM 5555 O O . CYS B 1 322 ? 11.476 -106.773 51.001 1.00 29.85 ? 393 CYS C O 1 ATOM 5556 C CB . CYS B 1 322 ? 9.398 -104.390 52.277 1.00 35.54 ? 393 CYS C CB 1 ATOM 5557 S SG . CYS B 1 322 ? 8.262 -105.138 51.103 1.00 34.64 ? 393 CYS C SG 1 ATOM 5558 N N . LEU B 1 323 ? 10.993 -106.740 53.204 1.00 24.01 ? 394 LEU C N 1 ATOM 5559 C CA . LEU B 1 323 ? 11.284 -108.151 53.420 1.00 24.42 ? 394 LEU C CA 1 ATOM 5560 C C . LEU B 1 323 ? 10.097 -108.865 54.050 1.00 31.52 ? 394 LEU C C 1 ATOM 5561 O O . LEU B 1 323 ? 9.326 -108.260 54.798 1.00 28.16 ? 394 LEU C O 1 ATOM 5562 C CB . LEU B 1 323 ? 12.516 -108.309 54.313 1.00 22.27 ? 394 LEU C CB 1 ATOM 5563 C CG . LEU B 1 323 ? 13.796 -107.612 53.844 1.00 28.83 ? 394 LEU C CG 1 ATOM 5564 C CD1 . LEU B 1 323 ? 14.853 -107.676 54.936 1.00 30.46 ? 394 LEU C CD1 1 ATOM 5565 C CD2 . LEU B 1 323 ? 14.317 -108.236 52.556 1.00 22.15 ? 394 LEU C CD2 1 ATOM 5566 N N . VAL B 1 324 ? 9.954 -110.149 53.734 1.00 28.63 ? 395 VAL C N 1 ATOM 5567 C CA . VAL B 1 324 ? 8.951 -111.000 54.367 1.00 23.54 ? 395 VAL C CA 1 ATOM 5568 C C . VAL B 1 324 ? 9.648 -112.133 55.109 1.00 26.29 ? 395 VAL C C 1 ATOM 5569 O O . VAL B 1 324 ? 10.464 -112.845 54.533 1.00 24.78 ? 395 VAL C O 1 ATOM 5570 C CB . VAL B 1 324 ? 7.960 -111.575 53.334 1.00 35.24 ? 395 VAL C CB 1 ATOM 5571 C CG1 . VAL B 1 324 ? 7.079 -112.658 53.959 1.00 38.28 ? 395 VAL C CG1 1 ATOM 5572 C CG2 . VAL B 1 324 ? 7.101 -110.462 52.759 1.00 35.41 ? 395 VAL C CG2 1 ATOM 5573 N N . SER B 1 325 ? 9.326 -112.305 56.387 1.00 28.85 ? 396 SER C N 1 ATOM 5574 C CA . SER B 1 325 ? 10.006 -113.308 57.203 1.00 29.78 ? 396 SER C CA 1 ATOM 5575 C C . SER B 1 325 ? 9.630 -114.727 56.797 1.00 24.45 ? 396 SER C C 1 ATOM 5576 O O . SER B 1 325 ? 8.453 -115.052 56.649 1.00 32.71 ? 396 SER C O 1 ATOM 5577 C CB . SER B 1 325 ? 9.690 -113.099 58.683 1.00 30.30 ? 396 SER C CB 1 ATOM 5578 O OG . SER B 1 325 ? 9.896 -111.751 59.046 1.00 30.67 ? 396 SER C OG 1 ATOM 5579 N N . ASP B 1 326 ? 10.647 -115.566 56.625 1.00 30.77 ? 397 ASP C N 1 ATOM 5580 C CA . ASP B 1 326 ? 10.460 -116.974 56.299 1.00 28.35 ? 397 ASP C CA 1 ATOM 5581 C C . ASP B 1 326 ? 11.755 -117.714 56.605 1.00 35.33 ? 397 ASP C C 1 ATOM 5582 O O . ASP B 1 326 ? 12.726 -117.623 55.854 1.00 27.78 ? 397 ASP C O 1 ATOM 5583 C CB . ASP B 1 326 ? 10.057 -117.150 54.832 1.00 33.04 ? 397 ASP C CB 1 ATOM 5584 C CG . ASP B 1 326 ? 9.813 -118.604 54.459 1.00 43.23 ? 397 ASP C CG 1 ATOM 5585 O OD1 . ASP B 1 326 ? 9.743 -119.457 55.369 1.00 39.96 ? 397 ASP C OD1 1 ATOM 5586 O OD2 . ASP B 1 326 ? 9.676 -118.891 53.250 1.00 35.36 ? 397 ASP C OD2 1 ATOM 5587 N N . SER B 1 327 ? 11.757 -118.447 57.713 1.00 31.22 ? 398 SER C N 1 ATOM 5588 C CA . SER B 1 327 ? 12.985 -119.002 58.274 1.00 36.78 ? 398 SER C CA 1 ATOM 5589 C C . SER B 1 327 ? 13.718 -119.939 57.316 1.00 29.89 ? 398 SER C C 1 ATOM 5590 O O . SER B 1 327 ? 14.940 -120.068 57.389 1.00 37.21 ? 398 SER C O 1 ATOM 5591 C CB . SER B 1 327 ? 12.676 -119.741 59.580 1.00 30.23 ? 398 SER C CB 1 ATOM 5592 O OG . SER B 1 327 ? 12.029 -120.976 59.334 1.00 39.91 ? 398 SER C OG 1 ATOM 5593 N N . ALA B 1 328 ? 12.979 -120.582 56.416 1.00 27.38 ? 399 ALA C N 1 ATOM 5594 C CA . ALA B 1 328 ? 13.580 -121.531 55.483 1.00 26.80 ? 399 ALA C CA 1 ATOM 5595 C C . ALA B 1 328 ? 13.970 -120.864 54.167 1.00 22.23 ? 399 ALA C C 1 ATOM 5596 O O . ALA B 1 328 ? 14.604 -121.487 53.313 1.00 29.74 ? 399 ALA C O 1 ATOM 5597 C CB . ALA B 1 328 ? 12.628 -122.683 55.223 1.00 31.90 ? 399 ALA C CB 1 ATOM 5598 N N . ALA B 1 329 ? 13.594 -119.601 54.004 1.00 18.04 ? 400 ALA C N 1 ATOM 5599 C CA . ALA B 1 329 ? 13.863 -118.884 52.765 1.00 22.04 ? 400 ALA C CA 1 ATOM 5600 C C . ALA B 1 329 ? 15.270 -118.304 52.741 1.00 30.21 ? 400 ALA C C 1 ATOM 5601 O O . ALA B 1 329 ? 15.848 -118.015 53.791 1.00 23.02 ? 400 ALA C O 1 ATOM 5602 C CB . ALA B 1 329 ? 12.847 -117.773 52.569 1.00 16.59 ? 400 ALA C CB 1 ATOM 5603 N N . VAL B 1 330 ? 15.817 -118.137 51.539 1.00 21.76 ? 401 VAL C N 1 ATOM 5604 C CA . VAL B 1 330 ? 17.088 -117.423 51.374 1.00 15.60 ? 401 VAL C CA 1 ATOM 5605 C C . VAL B 1 330 ? 17.038 -116.539 50.132 1.00 25.05 ? 401 VAL C C 1 ATOM 5606 O O . VAL B 1 330 ? 16.753 -117.015 49.033 1.00 21.50 ? 401 VAL C O 1 ATOM 5607 C CB . VAL B 1 330 ? 18.296 -118.380 51.261 1.00 19.72 ? 401 VAL C CB 1 ATOM 5608 C CG1 . VAL B 1 330 ? 19.599 -117.586 51.200 1.00 20.91 ? 401 VAL C CG1 1 ATOM 5609 C CG2 . VAL B 1 330 ? 18.334 -119.346 52.432 1.00 24.81 ? 401 VAL C CG2 1 ATOM 5610 N N . SER B 1 331 ? 17.324 -115.253 50.321 1.00 18.45 ? 402 SER C N 1 ATOM 5611 C CA . SER B 1 331 ? 17.267 -114.276 49.239 1.00 18.28 ? 402 SER C CA 1 ATOM 5612 C C . SER B 1 331 ? 18.638 -114.002 48.627 1.00 22.24 ? 402 SER C C 1 ATOM 5613 O O . SER B 1 331 ? 19.588 -113.654 49.331 1.00 19.46 ? 402 SER C O 1 ATOM 5614 C CB . SER B 1 331 ? 16.662 -112.971 49.746 1.00 18.20 ? 402 SER C CB 1 ATOM 5615 O OG . SER B 1 331 ? 15.264 -113.099 49.942 1.00 21.27 ? 402 SER C OG 1 ATOM 5616 N N . TYR B 1 332 ? 18.721 -114.162 47.309 1.00 25.27 ? 403 TYR C N 1 ATOM 5617 C CA . TYR B 1 332 ? 19.954 -113.945 46.563 1.00 16.43 ? 403 TYR C CA 1 ATOM 5618 C C . TYR B 1 332 ? 19.821 -112.834 45.528 1.00 23.80 ? 403 TYR C C 1 ATOM 5619 O O . TYR B 1 332 ? 18.711 -112.489 45.102 1.00 16.88 ? 403 TYR C O 1 ATOM 5620 C CB . TYR B 1 332 ? 20.375 -115.222 45.841 1.00 17.37 ? 403 TYR C CB 1 ATOM 5621 C CG . TYR B 1 332 ? 20.466 -116.447 46.704 1.00 17.72 ? 403 TYR C CG 1 ATOM 5622 C CD1 . TYR B 1 332 ? 21.576 -116.678 47.502 1.00 22.40 ? 403 TYR C CD1 1 ATOM 5623 C CD2 . TYR B 1 332 ? 19.453 -117.394 46.696 1.00 21.93 ? 403 TYR C CD2 1 ATOM 5624 C CE1 . TYR B 1 332 ? 21.665 -117.807 48.280 1.00 17.76 ? 403 TYR C CE1 1 ATOM 5625 C CE2 . TYR B 1 332 ? 19.533 -118.526 47.468 1.00 18.91 ? 403 TYR C CE2 1 ATOM 5626 C CZ . TYR B 1 332 ? 20.640 -118.729 48.257 1.00 17.45 ? 403 TYR C CZ 1 ATOM 5627 O OH . TYR B 1 332 ? 20.718 -119.861 49.027 1.00 21.19 ? 403 TYR C OH 1 ATOM 5628 N N . THR B 1 333 ? 20.972 -112.298 45.121 1.00 17.16 ? 404 THR C N 1 ATOM 5629 C CA . THR B 1 333 ? 21.062 -111.387 43.983 1.00 20.93 ? 404 THR C CA 1 ATOM 5630 C C . THR B 1 333 ? 22.114 -111.900 43.007 1.00 19.02 ? 404 THR C C 1 ATOM 5631 O O . THR B 1 333 ? 22.938 -112.747 43.359 1.00 16.67 ? 404 THR C O 1 ATOM 5632 C CB . THR B 1 333 ? 21.428 -109.949 44.407 1.00 21.26 ? 404 THR C CB 1 ATOM 5633 O OG1 . THR B 1 333 ? 22.817 -109.886 44.755 1.00 23.27 ? 404 THR C OG1 1 ATOM 5634 C CG2 . THR B 1 333 ? 20.575 -109.492 45.587 1.00 15.40 ? 404 THR C CG2 1 ATOM 5635 N N . ALA B 1 334 ? 22.089 -111.384 41.782 1.00 16.96 ? 405 ALA C N 1 ATOM 5636 C CA . ALA B 1 334 ? 23.041 -111.802 40.758 1.00 14.92 ? 405 ALA C CA 1 ATOM 5637 C C . ALA B 1 334 ? 24.483 -111.451 41.132 1.00 16.02 ? 405 ALA C C 1 ATOM 5638 O O . ALA B 1 334 ? 25.425 -112.050 40.615 1.00 19.28 ? 405 ALA C O 1 ATOM 5639 C CB . ALA B 1 334 ? 22.682 -111.170 39.421 1.00 16.97 ? 405 ALA C CB 1 ATOM 5640 N N . ALA B 1 335 ? 24.647 -110.483 42.029 1.00 16.42 ? 406 ALA C N 1 ATOM 5641 C CA . ALA B 1 335 ? 25.973 -110.001 42.407 1.00 20.16 ? 406 ALA C CA 1 ATOM 5642 C C . ALA B 1 335 ? 26.549 -110.747 43.606 1.00 19.89 ? 406 ALA C C 1 ATOM 5643 O O . ALA B 1 335 ? 27.762 -110.935 43.704 1.00 18.24 ? 406 ALA C O 1 ATOM 5644 C CB . ALA B 1 335 ? 25.915 -108.521 42.710 1.00 16.00 ? 406 ALA C CB 1 ATOM 5645 N N . GLY B 1 336 ? 25.674 -111.168 44.513 1.00 20.54 ? 407 GLY C N 1 ATOM 5646 C CA . GLY B 1 336 ? 26.097 -111.696 45.798 1.00 15.43 ? 407 GLY C CA 1 ATOM 5647 C C . GLY B 1 336 ? 26.574 -113.135 45.801 1.00 17.15 ? 407 GLY C C 1 ATOM 5648 O O . GLY B 1 336 ? 26.552 -113.823 44.779 1.00 19.06 ? 407 GLY C O 1 ATOM 5649 N N . SER B 1 337 ? 27.006 -113.583 46.977 1.00 14.59 ? 408 SER C N 1 ATOM 5650 C CA . SER B 1 337 ? 27.543 -114.925 47.166 1.00 16.43 ? 408 SER C CA 1 ATOM 5651 C C . SER B 1 337 ? 26.480 -115.905 47.640 1.00 12.35 ? 408 SER C C 1 ATOM 5652 O O . SER B 1 337 ? 25.402 -115.507 48.083 1.00 12.89 ? 408 SER C O 1 ATOM 5653 C CB . SER B 1 337 ? 28.680 -114.897 48.186 1.00 22.19 ? 408 SER C CB 1 ATOM 5654 O OG . SER B 1 337 ? 28.178 -114.558 49.466 1.00 20.06 ? 408 SER C OG 1 ATOM 5655 N N . LEU B 1 338 ? 26.803 -117.189 47.554 1.00 13.67 ? 409 LEU C N 1 ATOM 5656 C CA . LEU B 1 338 ? 25.928 -118.237 48.058 1.00 22.59 ? 409 LEU C CA 1 ATOM 5657 C C . LEU B 1 338 ? 25.861 -118.174 49.580 1.00 23.51 ? 409 LEU C C 1 ATOM 5658 O O . LEU B 1 338 ? 24.803 -118.366 50.176 1.00 22.82 ? 409 LEU C O 1 ATOM 5659 C CB . LEU B 1 338 ? 26.424 -119.612 47.605 1.00 14.95 ? 409 LEU C CB 1 ATOM 5660 C CG . LEU B 1 338 ? 25.694 -120.824 48.188 1.00 27.43 ? 409 LEU C CG 1 ATOM 5661 C CD1 . LEU B 1 338 ? 24.225 -120.788 47.812 1.00 20.07 ? 409 LEU C CD1 1 ATOM 5662 C CD2 . LEU B 1 338 ? 26.342 -122.117 47.715 1.00 24.34 ? 409 LEU C CD2 1 ATOM 5663 N N . SER B 1 339 ? 27.002 -117.894 50.200 1.00 26.87 ? 410 SER C N 1 ATOM 5664 C CA . SER B 1 339 ? 27.105 -117.896 51.654 1.00 23.49 ? 410 SER C CA 1 ATOM 5665 C C . SER B 1 339 ? 26.420 -116.686 52.277 1.00 21.99 ? 410 SER C C 1 ATOM 5666 O O . SER B 1 339 ? 26.387 -115.601 51.694 1.00 22.94 ? 410 SER C O 1 ATOM 5667 C CB . SER B 1 339 ? 28.576 -117.937 52.078 1.00 30.09 ? 410 SER C CB 1 ATOM 5668 O OG . SER B 1 339 ? 28.704 -117.783 53.480 1.00 43.68 ? 410 SER C OG 1 ATOM 5669 N N . GLU B 1 340 ? 25.870 -116.893 53.469 1.00 25.25 ? 411 GLU C N 1 ATOM 5670 C CA . GLU B 1 340 ? 25.248 -115.825 54.244 1.00 35.07 ? 411 GLU C CA 1 ATOM 5671 C C . GLU B 1 340 ? 26.254 -115.210 55.215 1.00 30.41 ? 411 GLU C C 1 ATOM 5672 O O . GLU B 1 340 ? 26.017 -114.137 55.774 1.00 34.82 ? 411 GLU C O 1 ATOM 5673 C CB . GLU B 1 340 ? 24.037 -116.359 55.009 1.00 36.15 ? 411 GLU C CB 1 ATOM 5674 C CG . GLU B 1 340 ? 23.062 -117.148 54.132 1.00 56.08 ? 411 GLU C CG 1 ATOM 5675 C CD . GLU B 1 340 ? 23.064 -118.650 54.391 1.00 84.60 ? 411 GLU C CD 1 ATOM 5676 O OE1 . GLU B 1 340 ? 22.196 -119.345 53.816 1.00 47.71 ? 411 GLU C OE1 1 ATOM 5677 O OE2 . GLU B 1 340 ? 23.924 -119.143 55.153 1.00 62.47 ? 411 GLU C OE2 1 ATOM 5678 N N . GLU B 1 341 ? 27.376 -115.899 55.405 1.00 31.96 ? 412 GLU C N 1 ATOM 5679 C CA . GLU B 1 341 ? 28.414 -115.469 56.337 1.00 38.63 ? 412 GLU C CA 1 ATOM 5680 C C . GLU B 1 341 ? 29.334 -114.424 55.715 1.00 38.37 ? 412 GLU C C 1 ATOM 5681 O O . GLU B 1 341 ? 29.704 -114.526 54.547 1.00 33.04 ? 412 GLU C O 1 ATOM 5682 C CB . GLU B 1 341 ? 29.252 -116.668 56.793 1.00 39.21 ? 412 GLU C CB 1 ATOM 5683 C CG . GLU B 1 341 ? 28.455 -117.873 57.280 1.00 67.04 ? 412 GLU C CG 1 ATOM 5684 C CD . GLU B 1 341 ? 27.922 -117.700 58.690 1.00 84.18 ? 412 GLU C CD 1 ATOM 5685 O OE1 . GLU B 1 341 ? 27.989 -118.672 59.472 1.00 84.92 ? 412 GLU C OE1 1 ATOM 5686 O OE2 . GLU B 1 341 ? 27.433 -116.598 59.016 1.00 64.24 ? 412 GLU C OE2 1 ATOM 5687 N N . THR B 1 342 ? 29.709 -113.428 56.508 1.00 32.57 ? 413 THR C N 1 ATOM 5688 C CA . THR B 1 342 ? 30.670 -112.423 56.074 1.00 32.69 ? 413 THR C CA 1 ATOM 5689 C C . THR B 1 342 ? 32.093 -112.958 56.244 1.00 30.01 ? 413 THR C C 1 ATOM 5690 O O . THR B 1 342 ? 32.531 -113.189 57.369 1.00 35.12 ? 413 THR C O 1 ATOM 5691 C CB . THR B 1 342 ? 30.510 -111.117 56.872 1.00 29.59 ? 413 THR C CB 1 ATOM 5692 O OG1 . THR B 1 342 ? 29.184 -110.608 56.694 1.00 34.75 ? 413 THR C OG1 1 ATOM 5693 C CG2 . THR B 1 342 ? 31.513 -110.067 56.411 1.00 36.76 ? 413 THR C CG2 1 ATOM 5694 N N . PRO B 1 343 ? 32.822 -113.161 55.133 1.00 28.05 ? 414 PRO C N 1 ATOM 5695 C CA . PRO B 1 343 ? 34.187 -113.679 55.262 1.00 33.02 ? 414 PRO C CA 1 ATOM 5696 C C . PRO B 1 343 ? 35.186 -112.593 55.660 1.00 28.10 ? 414 PRO C C 1 ATOM 5697 O O . PRO B 1 343 ? 34.935 -111.411 55.427 1.00 26.10 ? 414 PRO C O 1 ATOM 5698 C CB . PRO B 1 343 ? 34.484 -114.223 53.866 1.00 31.19 ? 414 PRO C CB 1 ATOM 5699 C CG . PRO B 1 343 ? 33.680 -113.367 52.956 1.00 28.42 ? 414 PRO C CG 1 ATOM 5700 C CD . PRO B 1 343 ? 32.455 -112.929 53.723 1.00 22.33 ? 414 PRO C CD 1 ATOM 5701 N N . ASN B 1 344 ? 36.307 -112.996 56.249 1.00 36.35 ? 415 ASN C N 1 ATOM 5702 C CA . ASN B 1 344 ? 37.256 -112.045 56.816 1.00 33.08 ? 415 ASN C CA 1 ATOM 5703 C C . ASN B 1 344 ? 37.893 -111.113 55.791 1.00 34.03 ? 415 ASN C C 1 ATOM 5704 O O . ASN B 1 344 ? 38.295 -110.001 56.133 1.00 33.95 ? 415 ASN C O 1 ATOM 5705 C CB . ASN B 1 344 ? 38.361 -112.792 57.565 1.00 40.89 ? 415 ASN C CB 1 ATOM 5706 C CG . ASN B 1 344 ? 37.855 -113.480 58.818 1.00 48.52 ? 415 ASN C CG 1 ATOM 5707 O OD1 . ASN B 1 344 ? 38.045 -114.682 58.999 1.00 59.27 ? 415 ASN C OD1 1 ATOM 5708 N ND2 . ASN B 1 344 ? 37.204 -112.718 59.691 1.00 48.97 ? 415 ASN C ND2 1 ATOM 5709 N N . PHE B 1 345 ? 37.986 -111.548 54.539 1.00 28.17 ? 416 PHE C N 1 ATOM 5710 C CA . PHE B 1 345 ? 38.710 -110.762 53.548 1.00 28.06 ? 416 PHE C CA 1 ATOM 5711 C C . PHE B 1 345 ? 37.902 -109.559 53.048 1.00 26.84 ? 416 PHE C C 1 ATOM 5712 O O . PHE B 1 345 ? 38.358 -108.839 52.160 1.00 28.19 ? 416 PHE C O 1 ATOM 5713 C CB . PHE B 1 345 ? 39.152 -111.645 52.371 1.00 29.27 ? 416 PHE C CB 1 ATOM 5714 C CG . PHE B 1 345 ? 38.023 -112.238 51.577 1.00 32.91 ? 416 PHE C CG 1 ATOM 5715 C CD1 . PHE B 1 345 ? 37.440 -111.531 50.539 1.00 32.68 ? 416 PHE C CD1 1 ATOM 5716 C CD2 . PHE B 1 345 ? 37.569 -113.518 51.846 1.00 35.74 ? 416 PHE C CD2 1 ATOM 5717 C CE1 . PHE B 1 345 ? 36.411 -112.080 49.800 1.00 33.70 ? 416 PHE C CE1 1 ATOM 5718 C CE2 . PHE B 1 345 ? 36.540 -114.074 51.110 1.00 33.63 ? 416 PHE C CE2 1 ATOM 5719 C CZ . PHE B 1 345 ? 35.961 -113.355 50.086 1.00 26.53 ? 416 PHE C CZ 1 ATOM 5720 N N . ILE B 1 346 ? 36.720 -109.332 53.624 1.00 25.68 ? 417 ILE C N 1 ATOM 5721 C CA . ILE B 1 346 ? 35.992 -108.081 53.397 1.00 24.49 ? 417 ILE C CA 1 ATOM 5722 C C . ILE B 1 346 ? 35.657 -107.404 54.728 1.00 24.52 ? 417 ILE C C 1 ATOM 5723 O O . ILE B 1 346 ? 34.856 -106.470 54.775 1.00 31.38 ? 417 ILE C O 1 ATOM 5724 C CB . ILE B 1 346 ? 34.687 -108.290 52.581 1.00 28.08 ? 417 ILE C CB 1 ATOM 5725 C CG1 . ILE B 1 346 ? 33.650 -109.112 53.356 1.00 26.44 ? 417 ILE C CG1 1 ATOM 5726 C CG2 . ILE B 1 346 ? 34.997 -108.954 51.243 1.00 25.17 ? 417 ILE C CG2 1 ATOM 5727 C CD1 . ILE B 1 346 ? 32.246 -108.947 52.819 1.00 28.31 ? 417 ILE C CD1 1 ATOM 5728 N N . ILE B 1 347 ? 36.277 -107.881 55.803 1.00 31.01 ? 418 ILE C N 1 ATOM 5729 C CA . ILE B 1 347 ? 36.117 -107.282 57.125 1.00 36.43 ? 418 ILE C CA 1 ATOM 5730 C C . ILE B 1 347 ? 37.323 -106.391 57.438 1.00 34.34 ? 418 ILE C C 1 ATOM 5731 O O . ILE B 1 347 ? 38.453 -106.877 57.469 1.00 31.36 ? 418 ILE C O 1 ATOM 5732 C CB . ILE B 1 347 ? 35.961 -108.363 58.213 1.00 39.07 ? 418 ILE C CB 1 ATOM 5733 C CG1 . ILE B 1 347 ? 34.580 -109.012 58.100 1.00 37.29 ? 418 ILE C CG1 1 ATOM 5734 C CG2 . ILE B 1 347 ? 36.143 -107.767 59.613 1.00 45.18 ? 418 ILE C CG2 1 ATOM 5735 C CD1 . ILE B 1 347 ? 34.362 -110.200 59.017 1.00 32.96 ? 418 ILE C CD1 1 ATOM 5736 N N . PRO B 1 348 ? 37.095 -105.084 57.668 1.00 32.73 ? 419 PRO C N 1 ATOM 5737 C CA . PRO B 1 348 ? 38.232 -104.221 58.012 1.00 44.61 ? 419 PRO C CA 1 ATOM 5738 C C . PRO B 1 348 ? 38.779 -104.518 59.405 1.00 49.59 ? 419 PRO C C 1 ATOM 5739 O O . PRO B 1 348 ? 38.034 -104.988 60.266 1.00 56.72 ? 419 PRO C O 1 ATOM 5740 C CB . PRO B 1 348 ? 37.645 -102.802 57.957 1.00 43.74 ? 419 PRO C CB 1 ATOM 5741 C CG . PRO B 1 348 ? 36.238 -102.939 57.468 1.00 38.41 ? 419 PRO C CG 1 ATOM 5742 C CD . PRO B 1 348 ? 35.820 -104.348 57.693 1.00 36.12 ? 419 PRO C CD 1 ATOM 5743 N N . SER B 1 349 ? 40.061 -104.242 59.622 1.00 69.87 ? 420 SER C N 1 ATOM 5744 C CA . SER B 1 349 ? 40.686 -104.469 60.921 1.00 83.80 ? 420 SER C CA 1 ATOM 5745 C C . SER B 1 349 ? 40.117 -103.536 61.986 1.00 79.10 ? 420 SER C C 1 ATOM 5746 O O . SER B 1 349 ? 40.051 -103.892 63.161 1.00 74.50 ? 420 SER C O 1 ATOM 5747 C CB . SER B 1 349 ? 42.200 -104.282 60.824 1.00 66.88 ? 420 SER C CB 1 ATOM 5748 O OG . SER B 1 349 ? 42.771 -105.216 59.925 1.00 73.64 ? 420 SER C OG 1 ATOM 5749 N N . ASN B 1 350 ? 39.710 -102.342 61.567 1.00 85.89 ? 421 ASN C N 1 ATOM 5750 C CA . ASN B 1 350 ? 39.170 -101.344 62.484 1.00 92.26 ? 421 ASN C CA 1 ATOM 5751 C C . ASN B 1 350 ? 37.692 -101.608 62.790 1.00 98.82 ? 421 ASN C C 1 ATOM 5752 O O . ASN B 1 350 ? 36.850 -101.472 61.904 1.00 88.63 ? 421 ASN C O 1 ATOM 5753 C CB . ASN B 1 350 ? 39.344 -99.942 61.894 1.00 99.62 ? 421 ASN C CB 1 ATOM 5754 C CG . ASN B 1 350 ? 39.059 -98.845 62.900 1.00 106.37 ? 421 ASN C CG 1 ATOM 5755 O OD1 . ASN B 1 350 ? 38.902 -99.104 64.093 1.00 99.07 ? 421 ASN C OD1 1 ATOM 5756 N ND2 . ASN B 1 350 ? 39.001 -97.607 62.424 1.00 85.11 ? 421 ASN C ND2 1 ATOM 5757 N N . PRO B 1 351 ? 37.365 -101.983 64.043 1.00 114.89 ? 422 PRO C N 1 ATOM 5758 C CA . PRO B 1 351 ? 35.969 -102.323 64.358 1.00 109.36 ? 422 PRO C CA 1 ATOM 5759 C C . PRO B 1 351 ? 35.003 -101.144 64.253 1.00 113.44 ? 422 PRO C C 1 ATOM 5760 O O . PRO B 1 351 ? 33.790 -101.350 64.186 1.00 110.33 ? 422 PRO C O 1 ATOM 5761 C CB . PRO B 1 351 ? 36.041 -102.812 65.813 1.00 103.68 ? 422 PRO C CB 1 ATOM 5762 C CG . PRO B 1 351 ? 37.480 -103.081 66.079 1.00 97.73 ? 422 PRO C CG 1 ATOM 5763 C CD . PRO B 1 351 ? 38.235 -102.128 65.223 1.00 104.15 ? 422 PRO C CD 1 ATOM 5764 N N . SER B 1 352 ? 35.536 -99.928 64.239 1.00 121.50 ? 423 SER C N 1 ATOM 5765 C CA . SER B 1 352 ? 34.709 -98.728 64.286 1.00 118.43 ? 423 SER C CA 1 ATOM 5766 C C . SER B 1 352 ? 33.969 -98.482 62.973 1.00 124.38 ? 423 SER C C 1 ATOM 5767 O O . SER B 1 352 ? 32.883 -97.899 62.968 1.00 112.13 ? 423 SER C O 1 ATOM 5768 C CB . SER B 1 352 ? 35.570 -97.510 64.626 1.00 104.96 ? 423 SER C CB 1 ATOM 5769 O OG . SER B 1 352 ? 36.508 -97.815 65.643 1.00 95.47 ? 423 SER C OG 1 ATOM 5770 N N . VAL B 1 353 ? 34.557 -98.934 61.868 1.00 132.20 ? 424 VAL C N 1 ATOM 5771 C CA . VAL B 1 353 ? 34.022 -98.652 60.539 1.00 131.83 ? 424 VAL C CA 1 ATOM 5772 C C . VAL B 1 353 ? 33.499 -99.913 59.849 1.00 123.97 ? 424 VAL C C 1 ATOM 5773 O O . VAL B 1 353 ? 33.555 -100.031 58.625 1.00 109.76 ? 424 VAL C O 1 ATOM 5774 C CB . VAL B 1 353 ? 35.089 -97.978 59.646 1.00 118.12 ? 424 VAL C CB 1 ATOM 5775 C CG1 . VAL B 1 353 ? 35.366 -96.564 60.136 1.00 103.03 ? 424 VAL C CG1 1 ATOM 5776 C CG2 . VAL B 1 353 ? 36.369 -98.803 59.614 1.00 102.23 ? 424 VAL C CG2 1 ATOM 5777 N N . THR B 1 354 ? 32.989 -100.852 60.642 1.00 123.40 ? 425 THR C N 1 ATOM 5778 C CA . THR B 1 354 ? 32.271 -102.001 60.099 1.00 113.25 ? 425 THR C CA 1 ATOM 5779 C C . THR B 1 354 ? 30.800 -101.633 59.932 1.00 115.91 ? 425 THR C C 1 ATOM 5780 O O . THR B 1 354 ? 30.234 -100.952 60.787 1.00 96.66 ? 425 THR C O 1 ATOM 5781 C CB . THR B 1 354 ? 32.383 -103.242 61.007 1.00 103.19 ? 425 THR C CB 1 ATOM 5782 O OG1 . THR B 1 354 ? 31.815 -102.956 62.292 1.00 84.27 ? 425 THR C OG1 1 ATOM 5783 C CG2 . THR B 1 354 ? 33.835 -103.659 61.174 1.00 84.46 ? 425 THR C CG2 1 ATOM 5784 N N . PRO B 1 355 ? 30.169 -102.075 58.831 1.00 109.28 ? 426 PRO C N 1 ATOM 5785 C CA . PRO B 1 355 ? 28.752 -101.750 58.654 1.00 109.30 ? 426 PRO C CA 1 ATOM 5786 C C . PRO B 1 355 ? 27.864 -102.633 59.520 1.00 107.12 ? 426 PRO C C 1 ATOM 5787 O O . PRO B 1 355 ? 28.350 -103.621 60.072 1.00 97.15 ? 426 PRO C O 1 ATOM 5788 C CB . PRO B 1 355 ? 28.520 -102.028 57.172 1.00 86.38 ? 426 PRO C CB 1 ATOM 5789 C CG . PRO B 1 355 ? 29.424 -103.174 56.895 1.00 81.62 ? 426 PRO C CG 1 ATOM 5790 C CD . PRO B 1 355 ? 30.665 -102.931 57.738 1.00 86.03 ? 426 PRO C CD 1 ATOM 5791 N N . PRO B 1 356 ? 26.576 -102.284 59.646 1.00 98.15 ? 427 PRO C N 1 ATOM 5792 C CA . PRO B 1 356 ? 25.656 -103.156 60.383 1.00 97.72 ? 427 PRO C CA 1 ATOM 5793 C C . PRO B 1 356 ? 25.394 -104.474 59.664 1.00 88.82 ? 427 PRO C C 1 ATOM 5794 O O . PRO B 1 356 ? 25.134 -104.481 58.459 1.00 76.57 ? 427 PRO C O 1 ATOM 5795 C CB . PRO B 1 356 ? 24.372 -102.323 60.470 1.00 81.33 ? 427 PRO C CB 1 ATOM 5796 C CG . PRO B 1 356 ? 24.465 -101.354 59.342 1.00 94.01 ? 427 PRO C CG 1 ATOM 5797 C CD . PRO B 1 356 ? 25.922 -101.045 59.191 1.00 82.05 ? 427 PRO C CD 1 ATOM 5798 N N . THR B 1 357 ? 25.477 -105.577 60.400 1.00 85.05 ? 428 THR C N 1 ATOM 5799 C CA . THR B 1 357 ? 25.050 -106.869 59.882 1.00 84.35 ? 428 THR C CA 1 ATOM 5800 C C . THR B 1 357 ? 23.532 -106.859 59.746 1.00 76.11 ? 428 THR C C 1 ATOM 5801 O O . THR B 1 357 ? 22.868 -105.979 60.296 1.00 57.00 ? 428 THR C O 1 ATOM 5802 C CB . THR B 1 357 ? 25.481 -108.033 60.803 1.00 77.43 ? 428 THR C CB 1 ATOM 5803 O OG1 . THR B 1 357 ? 24.942 -107.837 62.116 1.00 77.60 ? 428 THR C OG1 1 ATOM 5804 C CG2 . THR B 1 357 ? 26.996 -108.125 60.889 1.00 67.60 ? 428 THR C CG2 1 ATOM 5805 N N . PRO B 1 358 ? 22.977 -107.824 58.997 1.00 71.22 ? 429 PRO C N 1 ATOM 5806 C CA . PRO B 1 358 ? 21.519 -107.972 58.957 1.00 68.33 ? 429 PRO C CA 1 ATOM 5807 C C . PRO B 1 358 ? 20.917 -108.091 60.352 1.00 66.30 ? 429 PRO C C 1 ATOM 5808 O O . PRO B 1 358 ? 19.882 -107.487 60.628 1.00 60.67 ? 429 PRO C O 1 ATOM 5809 C CB . PRO B 1 358 ? 21.322 -109.265 58.165 1.00 71.47 ? 429 PRO C CB 1 ATOM 5810 C CG . PRO B 1 358 ? 22.506 -109.342 57.280 1.00 59.60 ? 429 PRO C CG 1 ATOM 5811 C CD . PRO B 1 358 ? 23.648 -108.720 58.040 1.00 73.05 ? 429 PRO C CD 1 ATOM 5812 N N . GLU B 1 359 ? 21.574 -108.856 61.220 1.00 79.62 ? 430 GLU C N 1 ATOM 5813 C CA . GLU B 1 359 ? 21.088 -109.060 62.579 1.00 76.04 ? 430 GLU C CA 1 ATOM 5814 C C . GLU B 1 359 ? 21.067 -107.757 63.366 1.00 67.83 ? 430 GLU C C 1 ATOM 5815 O O . GLU B 1 359 ? 20.285 -107.615 64.298 1.00 71.05 ? 430 GLU C O 1 ATOM 5816 C CB . GLU B 1 359 ? 21.948 -110.087 63.317 1.00 76.19 ? 430 GLU C CB 1 ATOM 5817 C CG . GLU B 1 359 ? 22.042 -111.431 62.621 1.00 97.18 ? 430 GLU C CG 1 ATOM 5818 C CD . GLU B 1 359 ? 23.442 -111.726 62.121 1.00 111.26 ? 430 GLU C CD 1 ATOM 5819 O OE1 . GLU B 1 359 ? 24.218 -112.364 62.864 1.00 104.66 ? 430 GLU C OE1 1 ATOM 5820 O OE2 . GLU B 1 359 ? 23.768 -111.319 60.986 1.00 92.81 ? 430 GLU C OE2 1 ATOM 5821 N N . THR B 1 360 ? 21.937 -106.819 62.995 1.00 65.71 ? 431 THR C N 1 ATOM 5822 C CA . THR B 1 360 ? 21.979 -105.504 63.633 1.00 63.44 ? 431 THR C CA 1 ATOM 5823 C C . THR B 1 360 ? 20.909 -104.587 63.050 1.00 53.09 ? 431 THR C C 1 ATOM 5824 O O . THR B 1 360 ? 20.107 -104.009 63.783 1.00 51.48 ? 431 THR C O 1 ATOM 5825 C CB . THR B 1 360 ? 23.361 -104.830 63.465 1.00 69.63 ? 431 THR C CB 1 ATOM 5826 O OG1 . THR B 1 360 ? 24.369 -105.621 64.105 1.00 64.71 ? 431 THR C OG1 1 ATOM 5827 C CG2 . THR B 1 360 ? 23.369 -103.428 64.076 1.00 51.93 ? 431 THR C CG2 1 ATOM 5828 N N . ALA B 1 361 ? 20.911 -104.453 61.728 1.00 44.82 ? 432 ALA C N 1 ATOM 5829 C CA . ALA B 1 361 ? 19.973 -103.573 61.041 1.00 44.56 ? 432 ALA C CA 1 ATOM 5830 C C . ALA B 1 361 ? 18.525 -104.007 61.262 1.00 39.01 ? 432 ALA C C 1 ATOM 5831 O O . ALA B 1 361 ? 17.612 -103.180 61.241 1.00 41.76 ? 432 ALA C O 1 ATOM 5832 C CB . ALA B 1 361 ? 20.287 -103.532 59.551 1.00 56.32 ? 432 ALA C CB 1 ATOM 5833 N N . LEU B 1 362 ? 18.326 -105.304 61.478 1.00 37.40 ? 433 LEU C N 1 ATOM 5834 C CA . LEU B 1 362 ? 16.991 -105.866 61.657 1.00 48.72 ? 433 LEU C CA 1 ATOM 5835 C C . LEU B 1 362 ? 16.731 -106.267 63.109 1.00 57.51 ? 433 LEU C C 1 ATOM 5836 O O . LEU B 1 362 ? 15.830 -107.062 63.385 1.00 46.12 ? 433 LEU C O 1 ATOM 5837 C CB . LEU B 1 362 ? 16.805 -107.079 60.740 1.00 42.05 ? 433 LEU C CB 1 ATOM 5838 C CG . LEU B 1 362 ? 17.048 -106.836 59.247 1.00 41.09 ? 433 LEU C CG 1 ATOM 5839 C CD1 . LEU B 1 362 ? 16.913 -108.133 58.463 1.00 41.46 ? 433 LEU C CD1 1 ATOM 5840 C CD2 . LEU B 1 362 ? 16.091 -105.787 58.709 1.00 40.00 ? 433 LEU C CD2 1 ATOM 5841 N N . GLN B 1 363 ? 17.514 -105.715 64.034 1.00 60.50 ? 434 GLN C N 1 ATOM 5842 C CA . GLN B 1 363 ? 17.359 -106.035 65.451 1.00 53.06 ? 434 GLN C CA 1 ATOM 5843 C C . GLN B 1 363 ? 16.261 -105.203 66.092 1.00 51.89 ? 434 GLN C C 1 ATOM 5844 O O . GLN B 1 363 ? 15.919 -104.119 65.617 1.00 53.92 ? 434 GLN C O 1 ATOM 5845 C CB . GLN B 1 363 ? 18.672 -105.818 66.210 1.00 58.13 ? 434 GLN C CB 1 ATOM 5846 C CG . GLN B 1 363 ? 18.890 -104.410 66.743 1.00 77.39 ? 434 GLN C CG 1 ATOM 5847 C CD . GLN B 1 363 ? 20.282 -104.224 67.321 1.00 76.95 ? 434 GLN C CD 1 ATOM 5848 O OE1 . GLN B 1 363 ? 21.159 -105.073 67.149 1.00 75.45 ? 434 GLN C OE1 1 ATOM 5849 N NE2 . GLN B 1 363 ? 20.490 -103.112 68.013 1.00 65.75 ? 434 GLN C NE2 1 ATOM 5850 N N . CYS B 1 364 ? 15.721 -105.727 67.184 1.00 50.95 ? 435 CYS C N 1 ATOM 5851 C CA . CYS B 1 364 ? 14.727 -105.022 67.976 1.00 60.10 ? 435 CYS C CA 1 ATOM 5852 C C . CYS B 1 364 ? 14.618 -105.698 69.335 1.00 60.65 ? 435 CYS C C 1 ATOM 5853 O O . CYS B 1 364 ? 15.175 -106.778 69.544 1.00 56.99 ? 435 CYS C O 1 ATOM 5854 C CB . CYS B 1 364 ? 13.369 -105.008 67.270 1.00 53.98 ? 435 CYS C CB 1 ATOM 5855 S SG . CYS B 1 364 ? 12.662 -106.651 66.980 1.00 71.66 ? 435 CYS C SG 1 ATOM 5856 N N . THR B 1 365 ? 13.914 -105.050 70.258 1.00 67.05 ? 436 THR C N 1 ATOM 5857 C CA . THR B 1 365 ? 13.617 -105.637 71.559 1.00 64.86 ? 436 THR C CA 1 ATOM 5858 C C . THR B 1 365 ? 12.113 -105.571 71.793 1.00 64.77 ? 436 THR C C 1 ATOM 5859 O O . THR B 1 365 ? 11.472 -104.565 71.485 1.00 63.84 ? 436 THR C O 1 ATOM 5860 C CB . THR B 1 365 ? 14.373 -104.922 72.696 1.00 78.43 ? 436 THR C CB 1 ATOM 5861 O OG1 . THR B 1 365 ? 14.052 -103.526 72.690 1.00 89.98 ? 436 THR C OG1 1 ATOM 5862 C CG2 . THR B 1 365 ? 15.879 -105.097 72.524 1.00 50.95 ? 436 THR C CG2 1 ATOM 5863 N N . ALA B 1 366 ? 11.564 -106.656 72.333 1.00 60.67 ? 437 ALA C N 1 ATOM 5864 C CA . ALA B 1 366 ? 10.119 -106.856 72.426 1.00 73.92 ? 437 ALA C CA 1 ATOM 5865 C C . ALA B 1 366 ? 9.373 -105.665 73.025 1.00 80.38 ? 437 ALA C C 1 ATOM 5866 O O . ALA B 1 366 ? 8.276 -105.329 72.582 1.00 72.56 ? 437 ALA C O 1 ATOM 5867 C CB . ALA B 1 366 ? 9.828 -108.109 73.242 1.00 71.82 ? 437 ALA C CB 1 ATOM 5868 N N . ASP B 1 367 ? 9.944 -105.087 74.076 1.00 90.92 ? 438 ASP C N 1 ATOM 5869 C CA . ASP B 1 367 ? 9.375 -103.933 74.766 1.00 91.43 ? 438 ASP C CA 1 ATOM 5870 C C . ASP B 1 367 ? 9.366 -102.624 73.989 1.00 89.14 ? 438 ASP C C 1 ATOM 5871 O O . ASP B 1 367 ? 8.395 -101.888 74.027 1.00 91.72 ? 438 ASP C O 1 ATOM 5872 C CB . ASP B 1 367 ? 10.080 -103.717 76.100 1.00 92.93 ? 438 ASP C CB 1 ATOM 5873 C CG . ASP B 1 367 ? 11.542 -104.037 76.024 1.00 98.56 ? 438 ASP C CG 1 ATOM 5874 O OD1 . ASP B 1 367 ? 12.370 -103.211 76.452 1.00 97.93 ? 438 ASP C OD1 1 ATOM 5875 O OD2 . ASP B 1 367 ? 11.860 -105.121 75.512 1.00 93.74 ? 438 ASP C OD2 1 ATOM 5876 N N . LYS B 1 368 ? 10.456 -102.339 73.293 1.00 89.16 ? 439 LYS C N 1 ATOM 5877 C CA . LYS B 1 368 ? 10.591 -101.101 72.525 1.00 92.14 ? 439 LYS C CA 1 ATOM 5878 C C . LYS B 1 368 ? 9.917 -101.192 71.155 1.00 89.62 ? 439 LYS C C 1 ATOM 5879 O O . LYS B 1 368 ? 9.635 -100.169 70.528 1.00 77.25 ? 439 LYS C O 1 ATOM 5880 C CB . LYS B 1 368 ? 12.066 -100.740 72.340 1.00 84.66 ? 439 LYS C CB 1 ATOM 5881 C CG . LYS B 1 368 ? 12.793 -100.367 73.622 1.00 90.43 ? 439 LYS C CG 1 ATOM 5882 C CD . LYS B 1 368 ? 14.175 -99.806 73.319 1.00 96.53 ? 439 LYS C CD 1 ATOM 5883 C CE . LYS B 1 368 ? 15.215 -100.296 74.314 1.00 109.94 ? 439 LYS C CE 1 ATOM 5884 N NZ . LYS B 1 368 ? 14.932 -99.843 75.704 1.00 111.40 ? 439 LYS C NZ 1 ATOM 5885 N N . PHE B 1 369 ? 9.664 -102.417 70.699 1.00 82.48 ? 440 PHE C N 1 ATOM 5886 C CA . PHE B 1 369 ? 9.108 -102.657 69.370 1.00 67.44 ? 440 PHE C CA 1 ATOM 5887 C C . PHE B 1 369 ? 7.745 -103.348 69.472 1.00 68.16 ? 440 PHE C C 1 ATOM 5888 O O . PHE B 1 369 ? 7.674 -104.575 69.532 1.00 61.67 ? 440 PHE C O 1 ATOM 5889 C CB . PHE B 1 369 ? 10.079 -103.503 68.540 1.00 70.41 ? 440 PHE C CB 1 ATOM 5890 C CG . PHE B 1 369 ? 9.856 -103.406 67.058 1.00 62.67 ? 440 PHE C CG 1 ATOM 5891 C CD1 . PHE B 1 369 ? 8.764 -104.014 66.461 1.00 56.89 ? 440 PHE C CD1 1 ATOM 5892 C CD2 . PHE B 1 369 ? 10.747 -102.709 66.259 1.00 63.26 ? 440 PHE C CD2 1 ATOM 5893 C CE1 . PHE B 1 369 ? 8.562 -103.921 65.097 1.00 62.42 ? 440 PHE C CE1 1 ATOM 5894 C CE2 . PHE B 1 369 ? 10.551 -102.613 64.896 1.00 59.14 ? 440 PHE C CE2 1 ATOM 5895 C CZ . PHE B 1 369 ? 9.458 -103.220 64.314 1.00 60.14 ? 440 PHE C CZ 1 ATOM 5896 N N . PRO B 1 370 ? 6.654 -102.561 69.497 1.00 66.91 ? 441 PRO C N 1 ATOM 5897 C CA . PRO B 1 370 ? 5.317 -103.149 69.640 1.00 67.94 ? 441 PRO C CA 1 ATOM 5898 C C . PRO B 1 370 ? 4.729 -103.648 68.321 1.00 62.02 ? 441 PRO C C 1 ATOM 5899 O O . PRO B 1 370 ? 5.045 -103.110 67.260 1.00 59.53 ? 441 PRO C O 1 ATOM 5900 C CB . PRO B 1 370 ? 4.492 -101.989 70.197 1.00 57.93 ? 441 PRO C CB 1 ATOM 5901 C CG . PRO B 1 370 ? 5.128 -100.776 69.606 1.00 61.92 ? 441 PRO C CG 1 ATOM 5902 C CD . PRO B 1 370 ? 6.602 -101.087 69.457 1.00 60.28 ? 441 PRO C CD 1 ATOM 5903 N N . ASP B 1 371 ? 3.882 -104.670 68.405 1.00 49.49 ? 442 ASP C N 1 ATOM 5904 C CA . ASP B 1 371 ? 3.199 -105.215 67.236 1.00 52.11 ? 442 ASP C CA 1 ATOM 5905 C C . ASP B 1 371 ? 2.382 -104.143 66.526 1.00 58.81 ? 442 ASP C C 1 ATOM 5906 O O . ASP B 1 371 ? 1.550 -103.476 67.143 1.00 74.65 ? 442 ASP C O 1 ATOM 5907 C CB . ASP B 1 371 ? 2.284 -106.375 67.641 1.00 51.62 ? 442 ASP C CB 1 ATOM 5908 C CG . ASP B 1 371 ? 3.051 -107.577 68.160 1.00 74.18 ? 442 ASP C CG 1 ATOM 5909 O OD1 . ASP B 1 371 ? 4.235 -107.421 68.526 1.00 65.53 ? 442 ASP C OD1 1 ATOM 5910 O OD2 . ASP B 1 371 ? 2.464 -108.680 68.209 1.00 64.99 ? 442 ASP C OD2 1 ATOM 5911 N N . SER B 1 372 ? 2.630 -103.985 65.228 1.00 59.11 ? 443 SER C N 1 ATOM 5912 C CA . SER B 1 372 ? 1.882 -103.044 64.400 1.00 57.21 ? 443 SER C CA 1 ATOM 5913 C C . SER B 1 372 ? 1.114 -103.781 63.310 1.00 56.34 ? 443 SER C C 1 ATOM 5914 O O . SER B 1 372 ? 1.700 -104.522 62.519 1.00 59.43 ? 443 SER C O 1 ATOM 5915 C CB . SER B 1 372 ? 2.819 -102.015 63.762 1.00 59.34 ? 443 SER C CB 1 ATOM 5916 O OG . SER B 1 372 ? 3.728 -101.482 64.709 1.00 70.29 ? 443 SER C OG 1 ATOM 5917 N N . PHE B 1 373 ? -0.201 -103.581 63.285 1.00 57.26 ? 444 PHE C N 1 ATOM 5918 C CA . PHE B 1 373 ? -1.039 -104.069 62.195 1.00 63.80 ? 444 PHE C CA 1 ATOM 5919 C C . PHE B 1 373 ? -1.387 -102.907 61.270 1.00 68.39 ? 444 PHE C C 1 ATOM 5920 O O . PHE B 1 373 ? -1.595 -101.783 61.729 1.00 66.66 ? 444 PHE C O 1 ATOM 5921 C CB . PHE B 1 373 ? -2.312 -104.727 62.731 1.00 60.74 ? 444 PHE C CB 1 ATOM 5922 C CG . PHE B 1 373 ? -2.059 -105.946 63.571 1.00 59.12 ? 444 PHE C CG 1 ATOM 5923 C CD1 . PHE B 1 373 ? -1.802 -105.829 64.927 1.00 56.24 ? 444 PHE C CD1 1 ATOM 5924 C CD2 . PHE B 1 373 ? -2.083 -107.211 63.006 1.00 57.90 ? 444 PHE C CD2 1 ATOM 5925 C CE1 . PHE B 1 373 ? -1.571 -106.949 65.703 1.00 65.47 ? 444 PHE C CE1 1 ATOM 5926 C CE2 . PHE B 1 373 ? -1.853 -108.336 63.777 1.00 60.00 ? 444 PHE C CE2 1 ATOM 5927 C CZ . PHE B 1 373 ? -1.597 -108.204 65.127 1.00 64.95 ? 444 PHE C CZ 1 ATOM 5928 N N . GLY B 1 374 ? -1.445 -103.184 59.970 1.00 66.35 ? 445 GLY C N 1 ATOM 5929 C CA . GLY B 1 374 ? -1.746 -102.167 58.978 1.00 67.67 ? 445 GLY C CA 1 ATOM 5930 C C . GLY B 1 374 ? -3.148 -102.322 58.428 1.00 76.34 ? 445 GLY C C 1 ATOM 5931 O O . GLY B 1 374 ? -3.827 -103.311 58.709 1.00 65.63 ? 445 GLY C O 1 ATOM 5932 N N . ALA B 1 375 ? -3.581 -101.339 57.644 1.00 71.32 ? 446 ALA C N 1 ATOM 5933 C CA . ALA B 1 375 ? -4.899 -101.372 57.024 1.00 71.29 ? 446 ALA C CA 1 ATOM 5934 C C . ALA B 1 375 ? -5.054 -102.610 56.155 1.00 73.33 ? 446 ALA C C 1 ATOM 5935 O O . ALA B 1 375 ? -4.110 -103.041 55.493 1.00 74.60 ? 446 ALA C O 1 ATOM 5936 C CB . ALA B 1 375 ? -5.129 -100.119 56.200 1.00 66.47 ? 446 ALA C CB 1 ATOM 5937 N N . CYS B 1 376 ? -6.253 -103.179 56.163 1.00 69.67 ? 447 CYS C N 1 ATOM 5938 C CA . CYS B 1 376 ? -6.528 -104.381 55.391 1.00 81.70 ? 447 CYS C CA 1 ATOM 5939 C C . CYS B 1 376 ? -6.440 -104.122 53.889 1.00 90.49 ? 447 CYS C C 1 ATOM 5940 O O . CYS B 1 376 ? -7.114 -103.236 53.364 1.00 74.60 ? 447 CYS C O 1 ATOM 5941 C CB . CYS B 1 376 ? -7.913 -104.928 55.732 1.00 71.57 ? 447 CYS C CB 1 ATOM 5942 S SG . CYS B 1 376 ? -8.269 -106.522 54.958 1.00 104.42 ? 447 CYS C SG 1 ATOM 5943 N N . ASP B 1 377 ? -5.602 -104.896 53.206 1.00 87.72 ? 448 ASP C N 1 ATOM 5944 C CA . ASP B 1 377 ? -5.581 -104.898 51.748 1.00 85.86 ? 448 ASP C CA 1 ATOM 5945 C C . ASP B 1 377 ? -6.758 -105.735 51.261 1.00 79.28 ? 448 ASP C C 1 ATOM 5946 O O . ASP B 1 377 ? -6.713 -106.964 51.288 1.00 77.65 ? 448 ASP C O 1 ATOM 5947 C CB . ASP B 1 377 ? -4.255 -105.449 51.215 1.00 85.16 ? 448 ASP C CB 1 ATOM 5948 C CG . ASP B 1 377 ? -4.303 -105.758 49.728 1.00 86.70 ? 448 ASP C CG 1 ATOM 5949 O OD1 . ASP B 1 377 ? -4.932 -104.987 48.974 1.00 93.48 ? 448 ASP C OD1 1 ATOM 5950 O OD2 . ASP B 1 377 ? -3.708 -106.776 49.313 1.00 73.63 ? 448 ASP C OD2 1 ATOM 5951 N N . VAL B 1 378 ? -7.816 -105.059 50.827 1.00 86.51 ? 449 VAL C N 1 ATOM 5952 C CA . VAL B 1 378 ? -9.079 -105.723 50.524 1.00 96.41 ? 449 VAL C CA 1 ATOM 5953 C C . VAL B 1 378 ? -9.003 -106.605 49.279 1.00 91.36 ? 449 VAL C C 1 ATOM 5954 O O . VAL B 1 378 ? -9.753 -107.574 49.158 1.00 86.54 ? 449 VAL C O 1 ATOM 5955 C CB . VAL B 1 378 ? -10.216 -104.697 50.338 1.00 93.38 ? 449 VAL C CB 1 ATOM 5956 C CG1 . VAL B 1 378 ? -10.434 -103.920 51.628 1.00 77.43 ? 449 VAL C CG1 1 ATOM 5957 C CG2 . VAL B 1 378 ? -9.913 -103.748 49.183 1.00 77.23 ? 449 VAL C CG2 1 ATOM 5958 N N . GLN B 1 379 ? -8.104 -106.270 48.359 1.00 87.96 ? 450 GLN C N 1 ATOM 5959 C CA . GLN B 1 379 ? -7.952 -107.044 47.131 1.00 80.72 ? 450 GLN C CA 1 ATOM 5960 C C . GLN B 1 379 ? -7.556 -108.489 47.428 1.00 80.63 ? 450 GLN C C 1 ATOM 5961 O O . GLN B 1 379 ? -8.048 -109.418 46.786 1.00 72.95 ? 450 GLN C O 1 ATOM 5962 C CB . GLN B 1 379 ? -6.913 -106.393 46.213 1.00 92.36 ? 450 GLN C CB 1 ATOM 5963 C CG . GLN B 1 379 ? -6.591 -107.218 44.961 1.00 110.09 ? 450 GLN C CG 1 ATOM 5964 C CD . GLN B 1 379 ? -6.485 -106.389 43.687 1.00 112.59 ? 450 GLN C CD 1 ATOM 5965 O OE1 . GLN B 1 379 ? -6.966 -105.258 43.617 1.00 106.61 ? 450 GLN C OE1 1 ATOM 5966 N NE2 . GLN B 1 379 ? -5.853 -106.961 42.667 1.00 91.78 ? 450 GLN C NE2 1 ATOM 5967 N N . ALA B 1 380 ? -6.669 -108.667 48.405 1.00 90.42 ? 451 ALA C N 1 ATOM 5968 C CA . ALA B 1 380 ? -6.191 -109.993 48.795 1.00 85.47 ? 451 ALA C CA 1 ATOM 5969 C C . ALA B 1 380 ? -6.718 -110.394 50.173 1.00 79.89 ? 451 ALA C C 1 ATOM 5970 O O . ALA B 1 380 ? -6.623 -111.556 50.567 1.00 71.14 ? 451 ALA C O 1 ATOM 5971 C CB . ALA B 1 380 ? -4.673 -110.026 48.783 1.00 79.09 ? 451 ALA C CB 1 ATOM 5972 N N . CYS B 1 381 ? -7.262 -109.421 50.900 1.00 88.39 ? 452 CYS C N 1 ATOM 5973 C CA . CYS B 1 381 ? -7.881 -109.663 52.203 1.00 94.69 ? 452 CYS C CA 1 ATOM 5974 C C . CYS B 1 381 ? -6.861 -110.120 53.249 1.00 83.74 ? 452 CYS C C 1 ATOM 5975 O O . CYS B 1 381 ? -7.140 -111.006 54.058 1.00 74.05 ? 452 CYS C O 1 ATOM 5976 C CB . CYS B 1 381 ? -9.003 -110.699 52.077 1.00 101.29 ? 452 CYS C CB 1 ATOM 5977 S SG . CYS B 1 381 ? -10.231 -110.620 53.403 1.00 128.34 ? 452 CYS C SG 1 ATOM 5978 N N . LYS B 1 382 ? -5.681 -109.508 53.218 1.00 82.69 ? 453 LYS C N 1 ATOM 5979 C CA . LYS B 1 382 ? -4.656 -109.726 54.235 1.00 62.02 ? 453 LYS C CA 1 ATOM 5980 C C . LYS B 1 382 ? -4.160 -108.379 54.743 1.00 61.37 ? 453 LYS C C 1 ATOM 5981 O O . LYS B 1 382 ? -4.485 -107.336 54.171 1.00 54.64 ? 453 LYS C O 1 ATOM 5982 C CB . LYS B 1 382 ? -3.488 -110.542 53.677 1.00 57.97 ? 453 LYS C CB 1 ATOM 5983 C CG . LYS B 1 382 ? -3.826 -111.985 53.337 1.00 59.05 ? 453 LYS C CG 1 ATOM 5984 C CD . LYS B 1 382 ? -2.628 -112.684 52.703 1.00 71.00 ? 453 LYS C CD 1 ATOM 5985 C CE . LYS B 1 382 ? -3.031 -113.646 51.592 1.00 88.09 ? 453 LYS C CE 1 ATOM 5986 N NZ . LYS B 1 382 ? -3.366 -115.004 52.100 1.00 95.41 ? 453 LYS C NZ 1 ATOM 5987 N N . ARG B 1 383 ? -3.380 -108.402 55.819 1.00 48.44 ? 454 ARG C N 1 ATOM 5988 C CA . ARG B 1 383 ? -2.817 -107.174 56.372 1.00 57.97 ? 454 ARG C CA 1 ATOM 5989 C C . ARG B 1 383 ? -1.402 -107.381 56.902 1.00 44.23 ? 454 ARG C C 1 ATOM 5990 O O . ARG B 1 383 ? -1.029 -108.482 57.310 1.00 44.10 ? 454 ARG C O 1 ATOM 5991 C CB . ARG B 1 383 ? -3.716 -106.637 57.485 1.00 60.67 ? 454 ARG C CB 1 ATOM 5992 C CG . ARG B 1 383 ? -4.067 -107.672 58.537 1.00 62.12 ? 454 ARG C CG 1 ATOM 5993 C CD . ARG B 1 383 ? -4.851 -107.059 59.679 1.00 68.84 ? 454 ARG C CD 1 ATOM 5994 N NE . ARG B 1 383 ? -5.062 -108.017 60.759 1.00 69.12 ? 454 ARG C NE 1 ATOM 5995 C CZ . ARG B 1 383 ? -5.399 -107.686 62.002 1.00 66.84 ? 454 ARG C CZ 1 ATOM 5996 N NH1 . ARG B 1 383 ? -5.562 -106.413 62.336 1.00 53.96 ? 454 ARG C NH1 1 ATOM 5997 N NH2 . ARG B 1 383 ? -5.567 -108.633 62.914 1.00 63.65 ? 454 ARG C NH2 1 ATOM 5998 N N . GLN B 1 384 ? -0.624 -106.304 56.893 1.00 42.77 ? 455 GLN C N 1 ATOM 5999 C CA . GLN B 1 384 ? 0.754 -106.336 57.367 1.00 49.92 ? 455 GLN C CA 1 ATOM 6000 C C . GLN B 1 384 ? 0.823 -106.520 58.877 1.00 50.30 ? 455 GLN C C 1 ATOM 6001 O O . GLN B 1 384 ? 0.190 -105.779 59.626 1.00 50.38 ? 455 GLN C O 1 ATOM 6002 C CB . GLN B 1 384 ? 1.480 -105.044 56.974 1.00 44.17 ? 455 GLN C CB 1 ATOM 6003 C CG . GLN B 1 384 ? 2.929 -104.947 57.452 1.00 42.53 ? 455 GLN C CG 1 ATOM 6004 C CD . GLN B 1 384 ? 3.851 -105.939 56.768 1.00 44.39 ? 455 GLN C CD 1 ATOM 6005 O OE1 . GLN B 1 384 ? 3.546 -106.453 55.690 1.00 36.08 ? 455 GLN C OE1 1 ATOM 6006 N NE2 . GLN B 1 384 ? 4.991 -106.211 57.393 1.00 42.43 ? 455 GLN C NE2 1 ATOM 6007 N N . LYS B 1 385 ? 1.588 -107.517 59.311 1.00 42.79 ? 456 LYS C N 1 ATOM 6008 C CA . LYS B 1 385 ? 1.971 -107.650 60.711 1.00 42.92 ? 456 LYS C CA 1 ATOM 6009 C C . LYS B 1 385 ? 3.483 -107.524 60.834 1.00 42.61 ? 456 LYS C C 1 ATOM 6010 O O . LYS B 1 385 ? 4.241 -108.339 60.291 1.00 40.42 ? 456 LYS C O 1 ATOM 6011 C CB . LYS B 1 385 ? 1.508 -108.982 61.302 1.00 44.06 ? 456 LYS C CB 1 ATOM 6012 C CG . LYS B 1 385 ? 1.734 -109.072 62.810 1.00 41.61 ? 456 LYS C CG 1 ATOM 6013 C CD . LYS B 1 385 ? 1.481 -110.465 63.356 1.00 52.67 ? 456 LYS C CD 1 ATOM 6014 C CE . LYS B 1 385 ? 1.525 -110.467 64.877 1.00 54.90 ? 456 LYS C CE 1 ATOM 6015 N NZ . LYS B 1 385 ? 1.568 -111.842 65.445 1.00 60.12 ? 456 LYS C NZ 1 ATOM 6016 N N . THR B 1 386 ? 3.900 -106.479 61.543 1.00 39.14 ? 457 THR C N 1 ATOM 6017 C CA . THR B 1 386 ? 5.299 -106.230 61.851 1.00 43.52 ? 457 THR C CA 1 ATOM 6018 C C . THR B 1 386 ? 5.499 -106.345 63.356 1.00 49.91 ? 457 THR C C 1 ATOM 6019 O O . THR B 1 386 ? 4.820 -105.666 64.127 1.00 53.69 ? 457 THR C O 1 ATOM 6020 C CB . THR B 1 386 ? 5.745 -104.834 61.372 1.00 42.24 ? 457 THR C CB 1 ATOM 6021 O OG1 . THR B 1 386 ? 5.491 -104.706 59.968 1.00 45.33 ? 457 THR C OG1 1 ATOM 6022 C CG2 . THR B 1 386 ? 7.230 -104.612 61.640 1.00 43.45 ? 457 THR C CG2 1 ATOM 6023 N N . SER B 1 387 ? 6.420 -107.208 63.775 1.00 41.30 ? 458 SER C N 1 ATOM 6024 C CA . SER B 1 387 ? 6.650 -107.416 65.202 1.00 41.86 ? 458 SER C CA 1 ATOM 6025 C C . SER B 1 387 ? 8.094 -107.789 65.513 1.00 46.54 ? 458 SER C C 1 ATOM 6026 O O . SER B 1 387 ? 8.925 -107.881 64.615 1.00 42.01 ? 458 SER C O 1 ATOM 6027 C CB . SER B 1 387 ? 5.715 -108.504 65.729 1.00 39.18 ? 458 SER C CB 1 ATOM 6028 O OG . SER B 1 387 ? 5.973 -109.745 65.098 1.00 44.91 ? 458 SER C OG 1 ATOM 6029 N N . CYS B 1 388 ? 8.380 -107.987 66.797 1.00 48.30 ? 459 CYS C N 1 ATOM 6030 C CA . CYS B 1 388 ? 9.701 -108.413 67.240 1.00 46.93 ? 459 CYS C CA 1 ATOM 6031 C C . CYS B 1 388 ? 9.628 -109.832 67.787 1.00 39.41 ? 459 CYS C C 1 ATOM 6032 O O . CYS B 1 388 ? 8.830 -110.121 68.681 1.00 47.80 ? 459 CYS C O 1 ATOM 6033 C CB . CYS B 1 388 ? 10.253 -107.464 68.305 1.00 56.59 ? 459 CYS C CB 1 ATOM 6034 S SG . CYS B 1 388 ? 12.021 -107.670 68.620 1.00 70.26 ? 459 CYS C SG 1 ATOM 6035 N N . VAL B 1 389 ? 10.456 -110.715 67.235 1.00 38.18 ? 460 VAL C N 1 ATOM 6036 C CA . VAL B 1 389 ? 10.516 -112.105 67.675 1.00 41.10 ? 460 VAL C CA 1 ATOM 6037 C C . VAL B 1 389 ? 11.958 -112.581 67.651 1.00 42.65 ? 460 VAL C C 1 ATOM 6038 O O . VAL B 1 389 ? 12.681 -112.351 66.679 1.00 40.64 ? 460 VAL C O 1 ATOM 6039 C CB . VAL B 1 389 ? 9.665 -113.029 66.786 1.00 40.26 ? 460 VAL C CB 1 ATOM 6040 C CG1 . VAL B 1 389 ? 9.677 -114.463 67.309 1.00 36.18 ? 460 VAL C CG1 1 ATOM 6041 C CG2 . VAL B 1 389 ? 8.235 -112.505 66.683 1.00 39.50 ? 460 VAL C CG2 1 ATOM 6042 N N . GLY B 1 390 ? 12.367 -113.249 68.722 1.00 40.39 ? 461 GLY C N 1 ATOM 6043 C CA . GLY B 1 390 ? 13.736 -113.704 68.860 1.00 32.05 ? 461 GLY C CA 1 ATOM 6044 C C . GLY B 1 390 ? 14.717 -112.557 68.714 1.00 29.68 ? 461 GLY C C 1 ATOM 6045 O O . GLY B 1 390 ? 15.850 -112.746 68.270 1.00 37.99 ? 461 GLY C O 1 ATOM 6046 N N . GLY B 1 391 ? 14.272 -111.359 69.081 1.00 31.85 ? 462 GLY C N 1 ATOM 6047 C CA . GLY B 1 391 ? 15.097 -110.169 68.983 1.00 35.72 ? 462 GLY C CA 1 ATOM 6048 C C . GLY B 1 391 ? 15.310 -109.696 67.554 1.00 44.89 ? 462 GLY C C 1 ATOM 6049 O O . GLY B 1 391 ? 16.216 -108.903 67.293 1.00 43.40 ? 462 GLY C O 1 ATOM 6050 N N . GLN B 1 392 ? 14.481 -110.182 66.632 1.00 40.71 ? 463 GLN C N 1 ATOM 6051 C CA . GLN B 1 392 ? 14.560 -109.780 65.227 1.00 41.84 ? 463 GLN C CA 1 ATOM 6052 C C . GLN B 1 392 ? 13.209 -109.303 64.710 1.00 36.00 ? 463 GLN C C 1 ATOM 6053 O O . GLN B 1 392 ? 12.158 -109.769 65.158 1.00 36.80 ? 463 GLN C O 1 ATOM 6054 C CB . GLN B 1 392 ? 15.061 -110.939 64.359 1.00 40.72 ? 463 GLN C CB 1 ATOM 6055 C CG . GLN B 1 392 ? 16.492 -111.361 64.646 1.00 53.83 ? 463 GLN C CG 1 ATOM 6056 C CD . GLN B 1 392 ? 17.501 -110.301 64.251 1.00 76.25 ? 463 GLN C CD 1 ATOM 6057 O OE1 . GLN B 1 392 ? 17.769 -110.095 63.068 1.00 77.19 ? 463 GLN C OE1 1 ATOM 6058 N NE2 . GLN B 1 392 ? 18.064 -109.618 65.244 1.00 63.78 ? 463 GLN C NE2 1 ATOM 6059 N N . ILE B 1 393 ? 13.246 -108.370 63.765 1.00 34.07 ? 464 ILE C N 1 ATOM 6060 C CA . ILE B 1 393 ? 12.031 -107.881 63.131 1.00 36.37 ? 464 ILE C CA 1 ATOM 6061 C C . ILE B 1 393 ? 11.399 -108.975 62.284 1.00 33.20 ? 464 ILE C C 1 ATOM 6062 O O . ILE B 1 393 ? 12.027 -109.498 61.361 1.00 34.06 ? 464 ILE C O 1 ATOM 6063 C CB . ILE B 1 393 ? 12.299 -106.652 62.236 1.00 39.30 ? 464 ILE C CB 1 ATOM 6064 C CG1 . ILE B 1 393 ? 12.842 -105.491 63.070 1.00 54.07 ? 464 ILE C CG1 1 ATOM 6065 C CG2 . ILE B 1 393 ? 11.017 -106.214 61.521 1.00 38.83 ? 464 ILE C CG2 1 ATOM 6066 C CD1 . ILE B 1 393 ? 13.418 -104.358 62.240 1.00 54.21 ? 464 ILE C CD1 1 ATOM 6067 N N . GLN B 1 394 ? 10.165 -109.330 62.628 1.00 30.42 ? 465 GLN C N 1 ATOM 6068 C CA . GLN B 1 394 ? 9.365 -110.247 61.832 1.00 32.78 ? 465 GLN C CA 1 ATOM 6069 C C . GLN B 1 394 ? 8.334 -109.453 61.034 1.00 36.14 ? 465 GLN C C 1 ATOM 6070 O O . GLN B 1 394 ? 7.619 -108.618 61.597 1.00 32.54 ? 465 GLN C O 1 ATOM 6071 C CB . GLN B 1 394 ? 8.684 -111.281 62.731 1.00 35.22 ? 465 GLN C CB 1 ATOM 6072 C CG . GLN B 1 394 ? 7.795 -112.273 61.996 1.00 29.45 ? 465 GLN C CG 1 ATOM 6073 C CD . GLN B 1 394 ? 7.201 -113.313 62.926 1.00 31.15 ? 465 GLN C CD 1 ATOM 6074 O OE1 . GLN B 1 394 ? 6.020 -113.253 63.268 1.00 35.30 ? 465 GLN C OE1 1 ATOM 6075 N NE2 . GLN B 1 394 ? 8.019 -114.274 63.339 1.00 34.81 ? 465 GLN C NE2 1 ATOM 6076 N N . SER B 1 395 ? 8.271 -109.722 59.733 1.00 35.06 ? 466 SER C N 1 ATOM 6077 C CA . SER B 1 395 ? 7.350 -109.049 58.830 1.00 33.55 ? 466 SER C CA 1 ATOM 6078 C C . SER B 1 395 ? 6.560 -110.079 58.040 1.00 33.73 ? 466 SER C C 1 ATOM 6079 O O . SER B 1 395 ? 7.134 -110.844 57.262 1.00 38.16 ? 466 SER C O 1 ATOM 6080 C CB . SER B 1 395 ? 8.111 -108.125 57.881 1.00 28.91 ? 466 SER C CB 1 ATOM 6081 O OG . SER B 1 395 ? 7.290 -107.724 56.800 1.00 32.95 ? 466 SER C OG 1 ATOM 6082 N N . THR B 1 396 ? 5.247 -110.105 58.251 1.00 29.92 ? 467 THR C N 1 ATOM 6083 C CA . THR B 1 396 ? 4.390 -111.076 57.574 1.00 35.85 ? 467 THR C CA 1 ATOM 6084 C C . THR B 1 396 ? 3.044 -110.476 57.181 1.00 38.79 ? 467 THR C C 1 ATOM 6085 O O . THR B 1 396 ? 2.732 -109.342 57.536 1.00 32.88 ? 467 THR C O 1 ATOM 6086 C CB . THR B 1 396 ? 4.136 -112.319 58.458 1.00 45.34 ? 467 THR C CB 1 ATOM 6087 O OG1 . THR B 1 396 ? 3.704 -111.907 59.760 1.00 50.01 ? 467 THR C OG1 1 ATOM 6088 C CG2 . THR B 1 396 ? 5.400 -113.156 58.589 1.00 40.05 ? 467 THR C CG2 1 ATOM 6089 N N . SER B 1 397 ? 2.268 -111.248 56.425 1.00 37.05 ? 468 SER C N 1 ATOM 6090 C CA . SER B 1 397 ? 0.897 -110.891 56.085 1.00 51.10 ? 468 SER C CA 1 ATOM 6091 C C . SER B 1 397 ? -0.055 -111.852 56.783 1.00 51.04 ? 468 SER C C 1 ATOM 6092 O O . SER B 1 397 ? 0.105 -113.072 56.693 1.00 46.96 ? 468 SER C O 1 ATOM 6093 C CB . SER B 1 397 ? 0.679 -110.923 54.570 1.00 48.83 ? 468 SER C CB 1 ATOM 6094 O OG . SER B 1 397 ? 1.194 -109.754 53.955 1.00 50.78 ? 468 SER C OG 1 ATOM 6095 N N . VAL B 1 398 ? -1.037 -111.296 57.485 1.00 49.19 ? 469 VAL C N 1 ATOM 6096 C CA . VAL B 1 398 ? -1.976 -112.096 58.264 1.00 62.16 ? 469 VAL C CA 1 ATOM 6097 C C . VAL B 1 398 ? -3.421 -111.771 57.912 1.00 62.07 ? 469 VAL C C 1 ATOM 6098 O O . VAL B 1 398 ? -3.706 -110.768 57.249 1.00 52.31 ? 469 VAL C O 1 ATOM 6099 C CB . VAL B 1 398 ? -1.773 -111.883 59.779 1.00 46.73 ? 469 VAL C CB 1 ATOM 6100 C CG1 . VAL B 1 398 ? -0.456 -112.497 60.228 1.00 46.73 ? 469 VAL C CG1 1 ATOM 6101 C CG2 . VAL B 1 398 ? -1.829 -110.400 60.128 1.00 49.39 ? 469 VAL C CG2 1 ATOM 6102 N N . ASP B 1 399 ? -4.322 -112.639 58.363 1.00 70.94 ? 470 ASP C N 1 ATOM 6103 C CA . ASP B 1 399 ? -5.751 -112.453 58.166 1.00 77.44 ? 470 ASP C CA 1 ATOM 6104 C C . ASP B 1 399 ? -6.209 -111.128 58.750 1.00 65.26 ? 470 ASP C C 1 ATOM 6105 O O . ASP B 1 399 ? -5.736 -110.707 59.805 1.00 63.08 ? 470 ASP C O 1 ATOM 6106 C CB . ASP B 1 399 ? -6.539 -113.594 58.813 1.00 79.82 ? 470 ASP C CB 1 ATOM 6107 C CG . ASP B 1 399 ? -6.195 -114.950 58.230 1.00 83.71 ? 470 ASP C CG 1 ATOM 6108 O OD1 . ASP B 1 399 ? -5.838 -115.015 57.035 1.00 85.22 ? 470 ASP C OD1 1 ATOM 6109 O OD2 . ASP B 1 399 ? -6.284 -115.952 58.969 1.00 85.72 ? 470 ASP C OD2 1 ATOM 6110 N N . CYS B 1 400 ? -7.130 -110.474 58.054 1.00 75.68 ? 471 CYS C N 1 ATOM 6111 C CA . CYS B 1 400 ? -7.763 -109.276 58.578 1.00 87.47 ? 471 CYS C CA 1 ATOM 6112 C C . CYS B 1 400 ? -8.753 -109.679 59.664 1.00 93.59 ? 471 CYS C C 1 ATOM 6113 O O . CYS B 1 400 ? -9.142 -110.845 59.749 1.00 77.42 ? 471 CYS C O 1 ATOM 6114 C CB . CYS B 1 400 ? -8.474 -108.503 57.467 1.00 93.81 ? 471 CYS C CB 1 ATOM 6115 S SG . CYS B 1 400 ? -7.402 -107.945 56.121 1.00 101.26 ? 471 CYS C SG 1 ATOM 6116 N N . THR B 1 401 ? -9.154 -108.723 60.496 1.00 92.35 ? 472 THR C N 1 ATOM 6117 C CA . THR B 1 401 ? -10.168 -108.986 61.509 1.00 94.75 ? 472 THR C CA 1 ATOM 6118 C C . THR B 1 401 ? -11.464 -109.392 60.817 1.00 103.19 ? 472 THR C C 1 ATOM 6119 O O . THR B 1 401 ? -11.726 -108.965 59.692 1.00 108.87 ? 472 THR C O 1 ATOM 6120 C CB . THR B 1 401 ? -10.417 -107.759 62.408 1.00 90.35 ? 472 THR C CB 1 ATOM 6121 O OG1 . THR B 1 401 ? -10.895 -106.665 61.615 1.00 81.80 ? 472 THR C OG1 1 ATOM 6122 C CG2 . THR B 1 401 ? -9.137 -107.346 63.120 1.00 69.07 ? 472 THR C CG2 1 ATOM 6123 N N . ALA B 1 402 ? -12.265 -110.220 61.482 1.00 108.48 ? 473 ALA C N 1 ATOM 6124 C CA . ALA B 1 402 ? -13.518 -110.704 60.905 1.00 111.28 ? 473 ALA C CA 1 ATOM 6125 C C . ALA B 1 402 ? -14.416 -109.541 60.491 1.00 113.11 ? 473 ALA C C 1 ATOM 6126 O O . ALA B 1 402 ? -15.266 -109.681 59.612 1.00 106.08 ? 473 ALA C O 1 ATOM 6127 C CB . ALA B 1 402 ? -14.239 -111.606 61.889 1.00 83.02 ? 473 ALA C CB 1 ATOM 6128 N N . ASP B 1 403 ? -14.217 -108.395 61.135 1.00 104.97 ? 474 ASP C N 1 ATOM 6129 C CA . ASP B 1 403 ? -14.886 -107.160 60.745 1.00 106.08 ? 474 ASP C CA 1 ATOM 6130 C C . ASP B 1 403 ? -14.497 -106.748 59.326 1.00 124.54 ? 474 ASP C C 1 ATOM 6131 O O . ASP B 1 403 ? -15.351 -106.600 58.452 1.00 116.11 ? 474 ASP C O 1 ATOM 6132 C CB . ASP B 1 403 ? -14.537 -106.038 61.727 1.00 100.70 ? 474 ASP C CB 1 ATOM 6133 C CG . ASP B 1 403 ? -14.824 -104.659 61.164 1.00 118.63 ? 474 ASP C CG 1 ATOM 6134 O OD1 . ASP B 1 403 ? -15.955 -104.162 61.350 1.00 127.02 ? 474 ASP C OD1 1 ATOM 6135 O OD2 . ASP B 1 403 ? -13.917 -104.069 60.539 1.00 112.18 ? 474 ASP C OD2 1 ATOM 6136 N N . GLU B 1 404 ? -13.197 -106.570 59.114 1.00 124.55 ? 475 GLU C N 1 ATOM 6137 C CA . GLU B 1 404 ? -12.665 -106.103 57.837 1.00 101.19 ? 475 GLU C CA 1 ATOM 6138 C C . GLU B 1 404 ? -12.881 -107.102 56.699 1.00 106.73 ? 475 GLU C C 1 ATOM 6139 O O . GLU B 1 404 ? -12.788 -106.741 55.526 1.00 116.34 ? 475 GLU C O 1 ATOM 6140 C CB . GLU B 1 404 ? -11.169 -105.811 57.975 1.00 108.50 ? 475 GLU C CB 1 ATOM 6141 C CG . GLU B 1 404 ? -10.829 -104.743 59.008 1.00 106.55 ? 475 GLU C CG 1 ATOM 6142 C CD . GLU B 1 404 ? -9.350 -104.711 59.360 1.00 104.80 ? 475 GLU C CD 1 ATOM 6143 O OE1 . GLU B 1 404 ? -8.790 -103.600 59.480 1.00 83.63 ? 475 GLU C OE1 1 ATOM 6144 O OE2 . GLU B 1 404 ? -8.748 -105.793 59.527 1.00 91.92 ? 475 GLU C OE2 1 ATOM 6145 N N . GLN B 1 405 ? -13.170 -108.353 57.047 1.00 103.61 ? 476 GLN C N 1 ATOM 6146 C CA . GLN B 1 405 ? -13.318 -109.415 56.052 1.00 110.47 ? 476 GLN C CA 1 ATOM 6147 C C . GLN B 1 405 ? -14.591 -109.288 55.212 1.00 116.81 ? 476 GLN C C 1 ATOM 6148 O O . GLN B 1 405 ? -14.859 -110.132 54.356 1.00 111.19 ? 476 GLN C O 1 ATOM 6149 C CB . GLN B 1 405 ? -13.302 -110.787 56.735 1.00 97.80 ? 476 GLN C CB 1 ATOM 6150 C CG . GLN B 1 405 ? -11.918 -111.266 57.151 1.00 96.64 ? 476 GLN C CG 1 ATOM 6151 C CD . GLN B 1 405 ? -11.906 -112.721 57.589 1.00 95.09 ? 476 GLN C CD 1 ATOM 6152 O OE1 . GLN B 1 405 ? -12.691 -113.535 57.103 1.00 86.55 ? 476 GLN C OE1 1 ATOM 6153 N NE2 . GLN B 1 405 ? -11.012 -113.052 58.514 1.00 92.27 ? 476 GLN C NE2 1 ATOM 6154 N N . ASN B 1 406 ? -15.371 -108.238 55.451 1.00 121.48 ? 477 ASN C N 1 ATOM 6155 C CA . ASN B 1 406 ? -16.628 -108.045 54.736 1.00 122.02 ? 477 ASN C CA 1 ATOM 6156 C C . ASN B 1 406 ? -16.433 -107.462 53.336 1.00 113.93 ? 477 ASN C C 1 ATOM 6157 O O . ASN B 1 406 ? -17.128 -107.847 52.396 1.00 108.68 ? 477 ASN C O 1 ATOM 6158 C CB . ASN B 1 406 ? -17.557 -107.137 55.546 1.00 118.66 ? 477 ASN C CB 1 ATOM 6159 C CG . ASN B 1 406 ? -17.968 -107.753 56.871 1.00 110.94 ? 477 ASN C CG 1 ATOM 6160 O OD1 . ASN B 1 406 ? -18.139 -108.968 56.978 1.00 113.51 ? 477 ASN C OD1 1 ATOM 6161 N ND2 . ASN B 1 406 ? -18.128 -106.914 57.888 1.00 84.14 ? 477 ASN C ND2 1 ATOM 6162 N N . GLU B 1 407 ? -15.484 -106.540 53.200 1.00 118.16 ? 478 GLU C N 1 ATOM 6163 C CA . GLU B 1 407 ? -15.269 -105.843 51.934 1.00 121.15 ? 478 GLU C CA 1 ATOM 6164 C C . GLU B 1 407 ? -14.560 -106.724 50.909 1.00 117.13 ? 478 GLU C C 1 ATOM 6165 O O . GLU B 1 407 ? -14.572 -106.428 49.713 1.00 116.27 ? 478 GLU C O 1 ATOM 6166 C CB . GLU B 1 407 ? -14.454 -104.564 52.151 1.00 102.12 ? 478 GLU C CB 1 ATOM 6167 C CG . GLU B 1 407 ? -15.037 -103.609 53.180 1.00 103.20 ? 478 GLU C CG 1 ATOM 6168 C CD . GLU B 1 407 ? -14.627 -103.955 54.598 1.00 111.08 ? 478 GLU C CD 1 ATOM 6169 O OE1 . GLU B 1 407 ? -13.424 -103.842 54.913 1.00 118.44 ? 478 GLU C OE1 1 ATOM 6170 O OE2 . GLU B 1 407 ? -15.506 -104.344 55.395 1.00 105.39 ? 478 GLU C OE2 1 ATOM 6171 N N . CYS B 1 408 ? -13.942 -107.803 51.380 1.00 110.43 ? 479 CYS C N 1 ATOM 6172 C CA . CYS B 1 408 ? -13.164 -108.683 50.513 1.00 120.90 ? 479 CYS C CA 1 ATOM 6173 C C . CYS B 1 408 ? -14.040 -109.329 49.443 1.00 96.76 ? 479 CYS C C 1 ATOM 6174 O O . CYS B 1 408 ? -14.884 -110.173 49.742 1.00 86.04 ? 479 CYS C O 1 ATOM 6175 C CB . CYS B 1 408 ? -12.467 -109.766 51.340 1.00 132.48 ? 479 CYS C CB 1 ATOM 6176 S SG . CYS B 1 408 ? -11.416 -109.138 52.674 1.00 144.10 ? 479 CYS C SG 1 ATOM 6177 N N . SER C 1 10 ? 7.492 -233.377 29.307 1.00 51.29 ? 68 SER E N 1 ATOM 6178 C CA . SER C 1 10 ? 7.124 -232.986 27.952 1.00 74.15 ? 68 SER E CA 1 ATOM 6179 C C . SER C 1 10 ? 5.718 -233.473 27.608 1.00 90.18 ? 68 SER E C 1 ATOM 6180 O O . SER C 1 10 ? 5.056 -234.113 28.427 1.00 70.25 ? 68 SER E O 1 ATOM 6181 C CB . SER C 1 10 ? 8.139 -233.532 26.946 1.00 83.47 ? 68 SER E CB 1 ATOM 6182 O OG . SER C 1 10 ? 9.434 -233.019 27.211 1.00 86.39 ? 68 SER E OG 1 ATOM 6183 N N . GLY C 1 11 ? 5.273 -233.167 26.393 1.00 77.91 ? 69 GLY E N 1 ATOM 6184 C CA . GLY C 1 11 ? 3.910 -233.442 25.975 1.00 63.51 ? 69 GLY E CA 1 ATOM 6185 C C . GLY C 1 11 ? 3.052 -232.213 26.204 1.00 50.86 ? 69 GLY E C 1 ATOM 6186 O O . GLY C 1 11 ? 1.865 -232.311 26.515 1.00 46.18 ? 69 GLY E O 1 ATOM 6187 N N . ASN C 1 12 ? 3.672 -231.047 26.054 1.00 59.78 ? 70 ASN E N 1 ATOM 6188 C CA . ASN C 1 12 ? 2.990 -229.770 26.225 1.00 38.48 ? 70 ASN E CA 1 ATOM 6189 C C . ASN C 1 12 ? 1.824 -229.641 25.243 1.00 32.54 ? 70 ASN E C 1 ATOM 6190 O O . ASN C 1 12 ? 2.045 -229.535 24.037 1.00 36.23 ? 70 ASN E O 1 ATOM 6191 C CB . ASN C 1 12 ? 3.983 -228.617 26.032 1.00 49.36 ? 70 ASN E CB 1 ATOM 6192 C CG . ASN C 1 12 ? 3.404 -227.265 26.413 1.00 35.78 ? 70 ASN E CG 1 ATOM 6193 O OD1 . ASN C 1 12 ? 2.196 -227.118 26.600 1.00 35.39 ? 70 ASN E OD1 1 ATOM 6194 N ND2 . ASN C 1 12 ? 4.271 -226.266 26.523 1.00 39.75 ? 70 ASN E ND2 1 ATOM 6195 N N . PRO C 1 13 ? 0.577 -229.646 25.749 1.00 26.71 ? 71 PRO E N 1 ATOM 6196 C CA . PRO C 1 13 ? -0.562 -229.588 24.825 1.00 39.11 ? 71 PRO E CA 1 ATOM 6197 C C . PRO C 1 13 ? -0.668 -228.251 24.096 1.00 58.16 ? 71 PRO E C 1 ATOM 6198 O O . PRO C 1 13 ? -1.423 -228.141 23.128 1.00 53.66 ? 71 PRO E O 1 ATOM 6199 C CB . PRO C 1 13 ? -1.770 -229.805 25.743 1.00 31.79 ? 71 PRO E CB 1 ATOM 6200 C CG . PRO C 1 13 ? -1.326 -229.311 27.067 1.00 33.55 ? 71 PRO E CG 1 ATOM 6201 C CD . PRO C 1 13 ? 0.140 -229.637 27.157 1.00 41.66 ? 71 PRO E CD 1 ATOM 6202 N N . PHE C 1 14 ? 0.083 -227.254 24.557 1.00 50.89 ? 72 PHE E N 1 ATOM 6203 C CA . PHE C 1 14 ? 0.077 -225.939 23.928 1.00 50.63 ? 72 PHE E CA 1 ATOM 6204 C C . PHE C 1 14 ? 1.185 -225.817 22.886 1.00 52.57 ? 72 PHE E C 1 ATOM 6205 O O . PHE C 1 14 ? 1.370 -224.758 22.284 1.00 55.41 ? 72 PHE E O 1 ATOM 6206 C CB . PHE C 1 14 ? 0.199 -224.850 24.990 1.00 36.43 ? 72 PHE E CB 1 ATOM 6207 C CG . PHE C 1 14 ? -0.986 -224.784 25.901 1.00 32.15 ? 72 PHE E CG 1 ATOM 6208 C CD1 . PHE C 1 14 ? -2.158 -224.180 25.483 1.00 34.71 ? 72 PHE E CD1 1 ATOM 6209 C CD2 . PHE C 1 14 ? -0.941 -225.351 27.161 1.00 28.70 ? 72 PHE E CD2 1 ATOM 6210 C CE1 . PHE C 1 14 ? -3.260 -224.128 26.311 1.00 35.20 ? 72 PHE E CE1 1 ATOM 6211 C CE2 . PHE C 1 14 ? -2.040 -225.302 27.996 1.00 34.50 ? 72 PHE E CE2 1 ATOM 6212 C CZ . PHE C 1 14 ? -3.201 -224.690 27.570 1.00 37.98 ? 72 PHE E CZ 1 ATOM 6213 N N . GLN C 1 15 ? 1.916 -226.912 22.686 1.00 48.45 ? 73 GLN E N 1 ATOM 6214 C CA . GLN C 1 15 ? 2.855 -227.046 21.576 1.00 53.00 ? 73 GLN E CA 1 ATOM 6215 C C . GLN C 1 15 ? 2.447 -228.248 20.725 1.00 59.04 ? 73 GLN E C 1 ATOM 6216 O O . GLN C 1 15 ? 3.264 -228.818 20.001 1.00 61.44 ? 73 GLN E O 1 ATOM 6217 C CB . GLN C 1 15 ? 4.288 -227.218 22.086 1.00 50.01 ? 73 GLN E CB 1 ATOM 6218 C CG . GLN C 1 15 ? 4.733 -226.169 23.099 1.00 55.96 ? 73 GLN E CG 1 ATOM 6219 C CD . GLN C 1 15 ? 4.968 -224.806 22.475 1.00 79.00 ? 73 GLN E CD 1 ATOM 6220 O OE1 . GLN C 1 15 ? 5.371 -224.702 21.318 1.00 63.45 ? 73 GLN E OE1 1 ATOM 6221 N NE2 . GLN C 1 15 ? 4.720 -223.751 23.243 1.00 63.09 ? 73 GLN E NE2 1 ATOM 6222 N N . ALA C 1 16 ? 1.176 -228.629 20.827 1.00 60.15 ? 74 ALA E N 1 ATOM 6223 C CA . ALA C 1 16 ? 0.661 -229.804 20.132 1.00 65.85 ? 74 ALA E CA 1 ATOM 6224 C C . ALA C 1 16 ? 0.692 -229.606 18.620 1.00 68.63 ? 74 ALA E C 1 ATOM 6225 O O . ALA C 1 16 ? 1.565 -230.142 17.936 1.00 73.47 ? 74 ALA E O 1 ATOM 6226 C CB . ALA C 1 16 ? -0.757 -230.117 20.600 1.00 49.99 ? 74 ALA E CB 1 ATOM 6227 N N . ASN C 1 17 ? -0.260 -228.831 18.108 1.00 50.43 ? 75 ASN E N 1 ATOM 6228 C CA . ASN C 1 17 ? -0.355 -228.570 16.676 1.00 61.45 ? 75 ASN E CA 1 ATOM 6229 C C . ASN C 1 17 ? 0.291 -227.240 16.291 1.00 64.13 ? 75 ASN E C 1 ATOM 6230 O O . ASN C 1 17 ? 0.578 -226.406 17.152 1.00 58.77 ? 75 ASN E O 1 ATOM 6231 C CB . ASN C 1 17 ? -1.821 -228.599 16.232 1.00 58.79 ? 75 ASN E CB 1 ATOM 6232 C CG . ASN C 1 17 ? -2.698 -227.656 17.031 1.00 63.73 ? 75 ASN E CG 1 ATOM 6233 O OD1 . ASN C 1 17 ? -2.732 -226.451 16.780 1.00 88.02 ? 75 ASN E OD1 1 ATOM 6234 N ND2 . ASN C 1 17 ? -3.424 -228.206 17.993 1.00 55.26 ? 75 ASN E ND2 1 ATOM 6235 N N . VAL C 1 18 ? 0.460 -227.049 14.997 1.00 56.52 ? 76 VAL E N 1 ATOM 6236 C CA . VAL C 1 18 ? 1.064 -225.852 14.480 1.00 67.02 ? 76 VAL E CA 1 ATOM 6237 C C . VAL C 1 18 ? 0.233 -224.644 14.862 1.00 54.24 ? 76 VAL E C 1 ATOM 6238 O O . VAL C 1 18 ? 0.772 -223.600 15.145 1.00 44.59 ? 76 VAL E O 1 ATOM 6239 C CB . VAL C 1 18 ? 1.260 -225.920 12.954 1.00 63.77 ? 76 VAL E CB 1 ATOM 6240 C CG1 . VAL C 1 18 ? 1.848 -227.256 12.561 1.00 61.12 ? 76 VAL E CG1 1 ATOM 6241 C CG2 . VAL C 1 18 ? -0.041 -225.686 12.222 1.00 44.24 ? 76 VAL E CG2 1 ATOM 6242 N N . GLU C 1 19 ? -1.079 -224.802 14.847 1.00 45.05 ? 77 GLU E N 1 ATOM 6243 C CA . GLU C 1 19 ? -1.963 -223.719 15.188 1.00 45.51 ? 77 GLU E CA 1 ATOM 6244 C C . GLU C 1 19 ? -1.760 -223.263 16.630 1.00 57.75 ? 77 GLU E C 1 ATOM 6245 O O . GLU C 1 19 ? -1.707 -222.078 16.893 1.00 50.46 ? 77 GLU E O 1 ATOM 6246 C CB . GLU C 1 19 ? -3.405 -224.147 14.987 1.00 52.82 ? 77 GLU E CB 1 ATOM 6247 C CG . GLU C 1 19 ? -4.181 -223.216 14.081 1.00 80.82 ? 77 GLU E CG 1 ATOM 6248 C CD . GLU C 1 19 ? -5.677 -223.434 14.151 1.00 101.46 ? 77 GLU E CD 1 ATOM 6249 O OE1 . GLU C 1 19 ? -6.226 -224.100 13.248 1.00 104.11 ? 77 GLU E OE1 1 ATOM 6250 O OE2 . GLU C 1 19 ? -6.301 -222.941 15.110 1.00 95.62 ? 77 GLU E OE2 1 ATOM 6251 N N . MET C 1 20 ? -1.644 -224.201 17.558 1.00 47.52 ? 78 MET E N 1 ATOM 6252 C CA . MET C 1 20 ? -1.418 -223.855 18.946 1.00 44.92 ? 78 MET E CA 1 ATOM 6253 C C . MET C 1 20 ? -0.052 -223.211 19.117 1.00 40.94 ? 78 MET E C 1 ATOM 6254 O O . MET C 1 20 ? 0.083 -222.232 19.818 1.00 38.95 ? 78 MET E O 1 ATOM 6255 C CB . MET C 1 20 ? -1.559 -225.074 19.841 1.00 50.60 ? 78 MET E CB 1 ATOM 6256 C CG . MET C 1 20 ? -1.578 -224.746 21.314 1.00 51.24 ? 78 MET E CG 1 ATOM 6257 S SD . MET C 1 20 ? -3.215 -224.300 21.883 1.00 60.74 ? 78 MET E SD 1 ATOM 6258 C CE . MET C 1 20 ? -4.076 -225.824 21.548 1.00 76.27 ? 78 MET E CE 1 ATOM 6259 N N . LYS C 1 21 ? 0.954 -223.770 18.459 1.00 35.33 ? 79 LYS E N 1 ATOM 6260 C CA . LYS C 1 21 ? 2.304 -223.214 18.497 1.00 42.02 ? 79 LYS E CA 1 ATOM 6261 C C . LYS C 1 21 ? 2.293 -221.772 18.010 1.00 44.90 ? 79 LYS E C 1 ATOM 6262 O O . LYS C 1 21 ? 2.887 -220.883 18.623 1.00 39.54 ? 79 LYS E O 1 ATOM 6263 C CB . LYS C 1 21 ? 3.258 -224.037 17.629 1.00 43.18 ? 79 LYS E CB 1 ATOM 6264 C CG . LYS C 1 21 ? 3.870 -225.248 18.308 1.00 62.38 ? 79 LYS E CG 1 ATOM 6265 C CD . LYS C 1 21 ? 4.922 -225.894 17.412 1.00 71.63 ? 79 LYS E CD 1 ATOM 6266 C CE . LYS C 1 21 ? 5.836 -226.829 18.187 1.00 87.41 ? 79 LYS E CE 1 ATOM 6267 N NZ . LYS C 1 21 ? 7.099 -227.098 17.443 1.00 84.65 ? 79 LYS E NZ 1 ATOM 6268 N N . THR C 1 22 ? 1.611 -221.564 16.889 1.00 39.57 ? 80 THR E N 1 ATOM 6269 C CA . THR C 1 22 ? 1.463 -220.248 16.289 1.00 51.41 ? 80 THR E CA 1 ATOM 6270 C C . THR C 1 22 ? 0.794 -219.300 17.269 1.00 41.33 ? 80 THR E C 1 ATOM 6271 O O . THR C 1 22 ? 1.270 -218.186 17.489 1.00 45.34 ? 80 THR E O 1 ATOM 6272 C CB . THR C 1 22 ? 0.642 -220.329 14.981 1.00 45.10 ? 80 THR E CB 1 ATOM 6273 O OG1 . THR C 1 22 ? 1.478 -220.817 13.925 1.00 44.71 ? 80 THR E OG1 1 ATOM 6274 C CG2 . THR C 1 22 ? 0.076 -218.965 14.580 1.00 53.80 ? 80 THR E CG2 1 ATOM 6275 N N . PHE C 1 23 ? -0.314 -219.748 17.850 1.00 42.57 ? 81 PHE E N 1 ATOM 6276 C CA . PHE C 1 23 ? -1.015 -218.959 18.852 1.00 39.41 ? 81 PHE E CA 1 ATOM 6277 C C . PHE C 1 23 ? -0.096 -218.576 20.007 1.00 49.74 ? 81 PHE E C 1 ATOM 6278 O O . PHE C 1 23 ? -0.040 -217.414 20.398 1.00 41.99 ? 81 PHE E O 1 ATOM 6279 C CB . PHE C 1 23 ? -2.227 -219.723 19.387 1.00 45.12 ? 81 PHE E CB 1 ATOM 6280 C CG . PHE C 1 23 ? -3.036 -218.944 20.382 1.00 36.72 ? 81 PHE E CG 1 ATOM 6281 C CD1 . PHE C 1 23 ? -3.847 -217.901 19.968 1.00 55.83 ? 81 PHE E CD1 1 ATOM 6282 C CD2 . PHE C 1 23 ? -2.984 -219.251 21.731 1.00 43.09 ? 81 PHE E CD2 1 ATOM 6283 C CE1 . PHE C 1 23 ? -4.591 -217.179 20.882 1.00 43.36 ? 81 PHE E CE1 1 ATOM 6284 C CE2 . PHE C 1 23 ? -3.727 -218.534 22.648 1.00 36.82 ? 81 PHE E CE2 1 ATOM 6285 C CZ . PHE C 1 23 ? -4.532 -217.496 22.222 1.00 47.93 ? 81 PHE E CZ 1 ATOM 6286 N N . MET C 1 24 ? 0.630 -219.547 20.546 1.00 35.19 ? 82 MET E N 1 ATOM 6287 C CA . MET C 1 24 ? 1.480 -219.293 21.705 1.00 39.88 ? 82 MET E CA 1 ATOM 6288 C C . MET C 1 24 ? 2.702 -218.433 21.384 1.00 40.22 ? 82 MET E C 1 ATOM 6289 O O . MET C 1 24 ? 3.137 -217.639 22.220 1.00 37.78 ? 82 MET E O 1 ATOM 6290 C CB . MET C 1 24 ? 1.935 -220.617 22.324 1.00 39.05 ? 82 MET E CB 1 ATOM 6291 C CG . MET C 1 24 ? 0.822 -221.386 23.024 1.00 47.31 ? 82 MET E CG 1 ATOM 6292 S SD . MET C 1 24 ? -0.012 -220.444 24.324 1.00 43.12 ? 82 MET E SD 1 ATOM 6293 C CE . MET C 1 24 ? 1.362 -220.039 25.398 1.00 40.05 ? 82 MET E CE 1 ATOM 6294 N N . GLU C 1 25 ? 3.223 -218.533 20.175 1.00 35.09 ? 83 GLU E N 1 ATOM 6295 C CA . GLU C 1 25 ? 4.374 -217.737 19.768 1.00 44.85 ? 83 GLU E CA 1 ATOM 6296 C C . GLU C 1 25 ? 4.097 -216.238 19.726 1.00 35.30 ? 83 GLU E C 1 ATOM 6297 O O . GLU C 1 25 ? 4.993 -215.428 19.836 1.00 34.12 ? 83 GLU E O 1 ATOM 6298 C CB . GLU C 1 25 ? 4.970 -218.225 18.455 1.00 45.43 ? 83 GLU E CB 1 ATOM 6299 C CG . GLU C 1 25 ? 6.281 -218.961 18.644 1.00 75.08 ? 83 GLU E CG 1 ATOM 6300 C CD . GLU C 1 25 ? 7.418 -218.034 19.037 1.00 87.17 ? 83 GLU E CD 1 ATOM 6301 O OE1 . GLU C 1 25 ? 7.517 -216.957 18.434 1.00 71.81 ? 83 GLU E OE1 1 ATOM 6302 O OE2 . GLU C 1 25 ? 8.215 -218.375 19.934 1.00 71.71 ? 83 GLU E OE2 1 ATOM 6303 N N . ARG C 1 26 ? 2.832 -215.889 19.593 1.00 33.30 ? 84 ARG E N 1 ATOM 6304 C CA . ARG C 1 26 ? 2.448 -214.499 19.538 1.00 39.63 ? 84 ARG E CA 1 ATOM 6305 C C . ARG C 1 26 ? 2.810 -213.808 20.849 1.00 47.38 ? 84 ARG E C 1 ATOM 6306 O O . ARG C 1 26 ? 2.962 -212.597 20.877 1.00 36.46 ? 84 ARG E O 1 ATOM 6307 C CB . ARG C 1 26 ? 0.956 -214.340 19.216 1.00 35.84 ? 84 ARG E CB 1 ATOM 6308 C CG . ARG C 1 26 ? 0.040 -214.336 20.423 1.00 45.54 ? 84 ARG E CG 1 ATOM 6309 C CD . ARG C 1 26 ? -1.376 -214.741 20.061 1.00 47.53 ? 84 ARG E CD 1 ATOM 6310 N NE . ARG C 1 26 ? -2.276 -213.615 19.862 1.00 51.56 ? 84 ARG E NE 1 ATOM 6311 C CZ . ARG C 1 26 ? -2.568 -213.093 18.678 1.00 64.99 ? 84 ARG E CZ 1 ATOM 6312 N NH1 . ARG C 1 26 ? -2.022 -213.590 17.583 1.00 56.77 ? 84 ARG E NH1 1 ATOM 6313 N NH2 . ARG C 1 26 ? -3.407 -212.076 18.588 1.00 69.02 ? 84 ARG E NH2 1 ATOM 6314 N N . PHE C 1 27 ? 2.924 -214.575 21.931 1.00 30.84 ? 85 PHE E N 1 ATOM 6315 C CA . PHE C 1 27 ? 3.213 -213.975 23.230 1.00 24.80 ? 85 PHE E CA 1 ATOM 6316 C C . PHE C 1 27 ? 4.706 -213.828 23.507 1.00 23.47 ? 85 PHE E C 1 ATOM 6317 O O . PHE C 1 27 ? 5.092 -213.382 24.583 1.00 39.49 ? 85 PHE E O 1 ATOM 6318 C CB . PHE C 1 27 ? 2.573 -214.801 24.345 1.00 24.56 ? 85 PHE E CB 1 ATOM 6319 C CG . PHE C 1 27 ? 1.076 -214.862 24.270 1.00 27.36 ? 85 PHE E CG 1 ATOM 6320 C CD1 . PHE C 1 27 ? 0.311 -213.744 24.559 1.00 24.42 ? 85 PHE E CD1 1 ATOM 6321 C CD2 . PHE C 1 27 ? 0.431 -216.037 23.920 1.00 29.90 ? 85 PHE E CD2 1 ATOM 6322 C CE1 . PHE C 1 27 ? -1.068 -213.794 24.494 1.00 23.03 ? 85 PHE E CE1 1 ATOM 6323 C CE2 . PHE C 1 27 ? -0.949 -216.094 23.853 1.00 31.87 ? 85 PHE E CE2 1 ATOM 6324 C CZ . PHE C 1 27 ? -1.699 -214.971 24.141 1.00 34.14 ? 85 PHE E CZ 1 ATOM 6325 N N . ASN C 1 28 ? 5.544 -214.206 22.547 1.00 25.76 ? 86 ASN E N 1 ATOM 6326 C CA . ASN C 1 28 ? 6.986 -214.039 22.694 1.00 24.87 ? 86 ASN E CA 1 ATOM 6327 C C . ASN C 1 28 ? 7.410 -212.706 22.085 1.00 29.02 ? 86 ASN E C 1 ATOM 6328 O O . ASN C 1 28 ? 7.606 -212.599 20.875 1.00 28.80 ? 86 ASN E O 1 ATOM 6329 C CB . ASN C 1 28 ? 7.743 -215.200 22.043 1.00 23.92 ? 86 ASN E CB 1 ATOM 6330 C CG . ASN C 1 28 ? 9.216 -215.220 22.423 1.00 34.32 ? 86 ASN E CG 1 ATOM 6331 O OD1 . ASN C 1 28 ? 9.765 -214.209 22.861 1.00 30.32 ? 86 ASN E OD1 1 ATOM 6332 N ND2 . ASN C 1 28 ? 9.863 -216.373 22.259 1.00 29.72 ? 86 ASN E ND2 1 ATOM 6333 N N . LEU C 1 29 ? 7.539 -211.690 22.933 1.00 24.49 ? 87 LEU E N 1 ATOM 6334 C CA . LEU C 1 29 ? 7.860 -210.342 22.478 1.00 28.53 ? 87 LEU E CA 1 ATOM 6335 C C . LEU C 1 29 ? 9.351 -210.188 22.197 1.00 29.66 ? 87 LEU E C 1 ATOM 6336 O O . LEU C 1 29 ? 9.770 -209.233 21.547 1.00 24.29 ? 87 LEU E O 1 ATOM 6337 C CB . LEU C 1 29 ? 7.394 -209.313 23.511 1.00 19.13 ? 87 LEU E CB 1 ATOM 6338 C CG . LEU C 1 29 ? 5.871 -209.167 23.585 1.00 16.05 ? 87 LEU E CG 1 ATOM 6339 C CD1 . LEU C 1 29 ? 5.452 -208.447 24.854 1.00 26.08 ? 87 LEU E CD1 1 ATOM 6340 C CD2 . LEU C 1 29 ? 5.335 -208.438 22.355 1.00 27.58 ? 87 LEU E CD2 1 ATOM 6341 N N . THR C 1 30 ? 10.151 -211.132 22.678 1.00 23.84 ? 88 THR E N 1 ATOM 6342 C CA . THR C 1 30 ? 11.570 -211.156 22.349 1.00 25.87 ? 88 THR E CA 1 ATOM 6343 C C . THR C 1 30 ? 11.766 -211.583 20.899 1.00 28.51 ? 88 THR E C 1 ATOM 6344 O O . THR C 1 30 ? 12.739 -211.196 20.250 1.00 34.70 ? 88 THR E O 1 ATOM 6345 C CB . THR C 1 30 ? 12.349 -212.115 23.268 1.00 29.19 ? 88 THR E CB 1 ATOM 6346 O OG1 . THR C 1 30 ? 12.241 -211.673 24.626 1.00 35.15 ? 88 THR E OG1 1 ATOM 6347 C CG2 . THR C 1 30 ? 13.820 -212.166 22.877 1.00 30.41 ? 88 THR E CG2 1 ATOM 6348 N N . HIS C 1 31 ? 10.827 -212.380 20.401 1.00 31.70 ? 89 HIS E N 1 ATOM 6349 C CA . HIS C 1 31 ? 10.936 -212.969 19.073 1.00 38.44 ? 89 HIS E CA 1 ATOM 6350 C C . HIS C 1 31 ? 10.376 -212.060 17.982 1.00 38.58 ? 89 HIS E C 1 ATOM 6351 O O . HIS C 1 31 ? 11.059 -211.760 17.006 1.00 32.92 ? 89 HIS E O 1 ATOM 6352 C CB . HIS C 1 31 ? 10.211 -214.314 19.038 1.00 37.19 ? 89 HIS E CB 1 ATOM 6353 C CG . HIS C 1 31 ? 10.424 -215.080 17.771 1.00 51.45 ? 89 HIS E CG 1 ATOM 6354 N ND1 . HIS C 1 31 ? 9.425 -215.810 17.165 1.00 59.97 ? 89 HIS E ND1 1 ATOM 6355 C CD2 . HIS C 1 31 ? 11.524 -215.232 16.996 1.00 46.69 ? 89 HIS E CD2 1 ATOM 6356 C CE1 . HIS C 1 31 ? 9.899 -216.377 16.070 1.00 56.35 ? 89 HIS E CE1 1 ATOM 6357 N NE2 . HIS C 1 31 ? 11.170 -216.042 15.945 1.00 51.77 ? 89 HIS E NE2 1 ATOM 6358 N N . HIS C 1 32 ? 9.128 -211.634 18.149 1.00 32.14 ? 90 HIS E N 1 ATOM 6359 C CA . HIS C 1 32 ? 8.434 -210.867 17.120 1.00 45.09 ? 90 HIS E CA 1 ATOM 6360 C C . HIS C 1 32 ? 8.683 -209.366 17.251 1.00 41.24 ? 90 HIS E C 1 ATOM 6361 O O . HIS C 1 32 ? 9.105 -208.722 16.291 1.00 37.14 ? 90 HIS E O 1 ATOM 6362 C CB . HIS C 1 32 ? 6.933 -211.163 17.171 1.00 53.89 ? 90 HIS E CB 1 ATOM 6363 C CG . HIS C 1 32 ? 6.588 -212.576 16.816 1.00 75.28 ? 90 HIS E CG 1 ATOM 6364 N ND1 . HIS C 1 32 ? 5.584 -213.280 17.445 1.00 58.98 ? 90 HIS E ND1 1 ATOM 6365 C CD2 . HIS C 1 32 ? 7.113 -213.416 15.892 1.00 73.50 ? 90 HIS E CD2 1 ATOM 6366 C CE1 . HIS C 1 32 ? 5.507 -214.492 16.926 1.00 50.22 ? 90 HIS E CE1 1 ATOM 6367 N NE2 . HIS C 1 32 ? 6.424 -214.601 15.982 1.00 61.07 ? 90 HIS E NE2 1 ATOM 6368 N N . HIS C 1 33 ? 8.432 -208.810 18.433 1.00 26.45 ? 91 HIS E N 1 ATOM 6369 C CA . HIS C 1 33 ? 8.595 -207.372 18.646 1.00 28.82 ? 91 HIS E CA 1 ATOM 6370 C C . HIS C 1 33 ? 10.067 -206.963 18.546 1.00 29.62 ? 91 HIS E C 1 ATOM 6371 O O . HIS C 1 33 ? 10.410 -206.051 17.794 1.00 20.06 ? 91 HIS E O 1 ATOM 6372 C CB . HIS C 1 33 ? 8.018 -206.965 20.002 1.00 25.58 ? 91 HIS E CB 1 ATOM 6373 C CG . HIS C 1 33 ? 7.980 -205.486 20.222 1.00 27.32 ? 91 HIS E CG 1 ATOM 6374 N ND1 . HIS C 1 33 ? 7.197 -204.639 19.469 1.00 23.57 ? 91 HIS E ND1 1 ATOM 6375 C CD2 . HIS C 1 33 ? 8.634 -204.703 21.110 1.00 24.59 ? 91 HIS E CD2 1 ATOM 6376 C CE1 . HIS C 1 33 ? 7.367 -203.397 19.887 1.00 27.41 ? 91 HIS E CE1 1 ATOM 6377 N NE2 . HIS C 1 33 ? 8.236 -203.409 20.881 1.00 27.05 ? 91 HIS E NE2 1 ATOM 6378 N N . GLN C 1 34 ? 10.919 -207.634 19.319 1.00 22.90 ? 92 GLN E N 1 ATOM 6379 C CA . GLN C 1 34 ? 12.380 -207.512 19.217 1.00 22.43 ? 92 GLN E CA 1 ATOM 6380 C C . GLN C 1 34 ? 12.945 -206.151 19.620 1.00 27.10 ? 92 GLN E C 1 ATOM 6381 O O . GLN C 1 34 ? 14.064 -205.807 19.234 1.00 21.63 ? 92 GLN E O 1 ATOM 6382 C CB . GLN C 1 34 ? 12.842 -207.820 17.790 1.00 33.29 ? 92 GLN E CB 1 ATOM 6383 C CG . GLN C 1 34 ? 12.432 -209.180 17.280 1.00 52.72 ? 92 GLN E CG 1 ATOM 6384 C CD . GLN C 1 34 ? 13.102 -209.525 15.967 1.00 56.14 ? 92 GLN E CD 1 ATOM 6385 O OE1 . GLN C 1 34 ? 14.235 -210.005 15.943 1.00 60.95 ? 92 GLN E OE1 1 ATOM 6386 N NE2 . GLN C 1 34 ? 12.408 -209.271 14.864 1.00 36.21 ? 92 GLN E NE2 1 ATOM 6387 N N . SER C 1 35 ? 12.197 -205.385 20.405 1.00 28.31 ? 93 SER E N 1 ATOM 6388 C CA . SER C 1 35 ? 12.667 -204.070 20.827 1.00 22.77 ? 93 SER E CA 1 ATOM 6389 C C . SER C 1 35 ? 12.027 -203.645 22.139 1.00 17.64 ? 93 SER E C 1 ATOM 6390 O O . SER C 1 35 ? 11.191 -204.354 22.690 1.00 20.05 ? 93 SER E O 1 ATOM 6391 C CB . SER C 1 35 ? 12.370 -203.031 19.745 1.00 20.45 ? 93 SER E CB 1 ATOM 6392 O OG . SER C 1 35 ? 13.161 -201.873 19.930 1.00 24.63 ? 93 SER E OG 1 ATOM 6393 N N . GLY C 1 36 ? 12.424 -202.479 22.637 1.00 21.55 ? 94 GLY E N 1 ATOM 6394 C CA . GLY C 1 36 ? 11.804 -201.917 23.820 1.00 15.85 ? 94 GLY E CA 1 ATOM 6395 C C . GLY C 1 36 ? 10.316 -201.730 23.602 1.00 18.82 ? 94 GLY E C 1 ATOM 6396 O O . GLY C 1 36 ? 9.862 -201.572 22.467 1.00 16.95 ? 94 GLY E O 1 ATOM 6397 N N . ILE C 1 37 ? 9.558 -201.757 24.693 1.00 17.40 ? 95 ILE E N 1 ATOM 6398 C CA . ILE C 1 37 ? 8.107 -201.623 24.636 1.00 18.05 ? 95 ILE E CA 1 ATOM 6399 C C . ILE C 1 37 ? 7.685 -200.339 25.339 1.00 20.80 ? 95 ILE E C 1 ATOM 6400 O O . ILE C 1 37 ? 6.970 -199.514 24.769 1.00 18.55 ? 95 ILE E O 1 ATOM 6401 C CB . ILE C 1 37 ? 7.413 -202.838 25.279 1.00 20.22 ? 95 ILE E CB 1 ATOM 6402 C CG1 . ILE C 1 37 ? 7.742 -204.103 24.481 1.00 18.19 ? 95 ILE E CG1 1 ATOM 6403 C CG2 . ILE C 1 37 ? 5.902 -202.641 25.326 1.00 20.06 ? 95 ILE E CG2 1 ATOM 6404 C CD1 . ILE C 1 37 ? 7.501 -205.384 25.235 1.00 25.07 ? 95 ILE E CD1 1 ATOM 6405 N N . TYR C 1 38 ? 8.135 -200.180 26.580 1.00 18.52 ? 96 TYR E N 1 ATOM 6406 C CA . TYR C 1 38 ? 7.907 -198.953 27.332 1.00 18.69 ? 96 TYR E CA 1 ATOM 6407 C C . TYR C 1 38 ? 8.527 -197.791 26.562 1.00 16.30 ? 96 TYR E C 1 ATOM 6408 O O . TYR C 1 38 ? 7.833 -196.854 26.172 1.00 15.00 ? 96 TYR E O 1 ATOM 6409 C CB . TYR C 1 38 ? 8.498 -199.070 28.740 1.00 16.00 ? 96 TYR E CB 1 ATOM 6410 C CG . TYR C 1 38 ? 8.168 -197.918 29.663 1.00 12.84 ? 96 TYR E CG 1 ATOM 6411 C CD1 . TYR C 1 38 ? 6.861 -197.679 30.069 1.00 16.65 ? 96 TYR E CD1 1 ATOM 6412 C CD2 . TYR C 1 38 ? 9.166 -197.081 30.145 1.00 16.82 ? 96 TYR E CD2 1 ATOM 6413 C CE1 . TYR C 1 38 ? 6.557 -196.632 30.917 1.00 20.54 ? 96 TYR E CE1 1 ATOM 6414 C CE2 . TYR C 1 38 ? 8.870 -196.032 30.995 1.00 20.84 ? 96 TYR E CE2 1 ATOM 6415 C CZ . TYR C 1 38 ? 7.566 -195.813 31.377 1.00 22.56 ? 96 TYR E CZ 1 ATOM 6416 O OH . TYR C 1 38 ? 7.272 -194.770 32.222 1.00 27.58 ? 96 TYR E OH 1 ATOM 6417 N N . VAL C 1 39 ? 9.835 -197.878 26.337 1.00 14.72 ? 97 VAL E N 1 ATOM 6418 C CA . VAL C 1 39 ? 10.547 -196.977 25.434 1.00 14.52 ? 97 VAL E CA 1 ATOM 6419 C C . VAL C 1 39 ? 11.189 -197.795 24.320 1.00 22.07 ? 97 VAL E C 1 ATOM 6420 O O . VAL C 1 39 ? 11.999 -198.683 24.586 1.00 18.33 ? 97 VAL E O 1 ATOM 6421 C CB . VAL C 1 39 ? 11.633 -196.165 26.165 1.00 15.46 ? 97 VAL E CB 1 ATOM 6422 C CG1 . VAL C 1 39 ? 12.497 -195.395 25.171 1.00 18.28 ? 97 VAL E CG1 1 ATOM 6423 C CG2 . VAL C 1 39 ? 10.998 -195.211 27.157 1.00 14.64 ? 97 VAL E CG2 1 ATOM 6424 N N . ASP C 1 40 ? 10.830 -197.479 23.078 1.00 19.18 ? 98 ASP E N 1 ATOM 6425 C CA . ASP C 1 40 ? 11.326 -198.198 21.906 1.00 19.08 ? 98 ASP E CA 1 ATOM 6426 C C . ASP C 1 40 ? 12.342 -197.349 21.147 1.00 19.41 ? 98 ASP E C 1 ATOM 6427 O O . ASP C 1 40 ? 11.982 -196.363 20.508 1.00 17.20 ? 98 ASP E O 1 ATOM 6428 C CB . ASP C 1 40 ? 10.158 -198.577 20.989 1.00 20.88 ? 98 ASP E CB 1 ATOM 6429 C CG . ASP C 1 40 ? 10.595 -199.358 19.752 1.00 22.22 ? 98 ASP E CG 1 ATOM 6430 O OD1 . ASP C 1 40 ? 11.810 -199.561 19.542 1.00 20.09 ? 98 ASP E OD1 1 ATOM 6431 O OD2 . ASP C 1 40 ? 9.706 -199.767 18.975 1.00 18.36 ? 98 ASP E OD2 1 ATOM 6432 N N . LEU C 1 41 ? 13.609 -197.746 21.218 1.00 14.08 ? 99 LEU E N 1 ATOM 6433 C CA . LEU C 1 41 ? 14.679 -197.081 20.483 1.00 15.36 ? 99 LEU E CA 1 ATOM 6434 C C . LEU C 1 41 ? 15.676 -198.131 19.998 1.00 23.23 ? 99 LEU E C 1 ATOM 6435 O O . LEU C 1 41 ? 16.882 -198.008 20.205 1.00 23.68 ? 99 LEU E O 1 ATOM 6436 C CB . LEU C 1 41 ? 15.369 -196.035 21.361 1.00 19.21 ? 99 LEU E CB 1 ATOM 6437 C CG . LEU C 1 41 ? 14.508 -194.841 21.785 1.00 21.83 ? 99 LEU E CG 1 ATOM 6438 C CD1 . LEU C 1 41 ? 15.245 -193.997 22.807 1.00 18.38 ? 99 LEU E CD1 1 ATOM 6439 C CD2 . LEU C 1 41 ? 14.127 -193.994 20.582 1.00 23.38 ? 99 LEU E CD2 1 ATOM 6440 N N . GLY C 1 42 ? 15.153 -199.159 19.338 1.00 23.43 ? 100 GLY E N 1 ATOM 6441 C CA . GLY C 1 42 ? 15.914 -200.362 19.059 1.00 26.28 ? 100 GLY E CA 1 ATOM 6442 C C . GLY C 1 42 ? 16.915 -200.272 17.925 1.00 30.61 ? 100 GLY E C 1 ATOM 6443 O O . GLY C 1 42 ? 17.821 -201.103 17.844 1.00 27.42 ? 100 GLY E O 1 ATOM 6444 N N . GLN C 1 43 ? 16.760 -199.283 17.049 1.00 26.58 ? 101 GLN E N 1 ATOM 6445 C CA . GLN C 1 43 ? 17.645 -199.158 15.896 1.00 23.15 ? 101 GLN E CA 1 ATOM 6446 C C . GLN C 1 43 ? 18.439 -197.859 15.911 1.00 26.34 ? 101 GLN E C 1 ATOM 6447 O O . GLN C 1 43 ? 18.068 -196.896 16.583 1.00 28.78 ? 101 GLN E O 1 ATOM 6448 C CB . GLN C 1 43 ? 16.837 -199.263 14.600 1.00 25.77 ? 101 GLN E CB 1 ATOM 6449 C CG . GLN C 1 43 ? 16.740 -200.687 14.062 1.00 36.86 ? 101 GLN E CG 1 ATOM 6450 C CD . GLN C 1 43 ? 15.624 -200.877 13.046 1.00 44.18 ? 101 GLN E CD 1 ATOM 6451 O OE1 . GLN C 1 43 ? 15.151 -201.995 12.837 1.00 38.55 ? 101 GLN E OE1 1 ATOM 6452 N NE2 . GLN C 1 43 ? 15.201 -199.790 12.406 1.00 39.36 ? 101 GLN E NE2 1 ATOM 6453 N N . ASP C 1 44 ? 19.550 -197.866 15.181 1.00 25.21 ? 102 ASP E N 1 ATOM 6454 C CA . ASP C 1 44 ? 20.347 -196.670 14.948 1.00 25.90 ? 102 ASP E CA 1 ATOM 6455 C C . ASP C 1 44 ? 20.396 -196.408 13.450 1.00 36.81 ? 102 ASP E C 1 ATOM 6456 O O . ASP C 1 44 ? 20.538 -197.339 12.656 1.00 28.44 ? 102 ASP E O 1 ATOM 6457 C CB . ASP C 1 44 ? 21.762 -196.824 15.511 1.00 35.35 ? 102 ASP E CB 1 ATOM 6458 C CG . ASP C 1 44 ? 21.779 -196.948 17.023 1.00 50.96 ? 102 ASP E CG 1 ATOM 6459 O OD1 . ASP C 1 44 ? 21.824 -195.904 17.708 1.00 49.77 ? 102 ASP E OD1 1 ATOM 6460 O OD2 . ASP C 1 44 ? 21.752 -198.091 17.528 1.00 48.28 ? 102 ASP E OD2 1 ATOM 6461 N N . LYS C 1 45 ? 20.266 -195.143 13.068 1.00 29.18 ? 103 LYS E N 1 ATOM 6462 C CA . LYS C 1 45 ? 20.281 -194.765 11.661 1.00 27.90 ? 103 LYS E CA 1 ATOM 6463 C C . LYS C 1 45 ? 21.092 -193.501 11.450 1.00 30.79 ? 103 LYS E C 1 ATOM 6464 O O . LYS C 1 45 ? 21.054 -192.578 12.265 1.00 32.51 ? 103 LYS E O 1 ATOM 6465 C CB . LYS C 1 45 ? 18.855 -194.570 11.139 1.00 27.79 ? 103 LYS E CB 1 ATOM 6466 C CG . LYS C 1 45 ? 18.056 -195.858 11.019 1.00 28.95 ? 103 LYS E CG 1 ATOM 6467 C CD . LYS C 1 45 ? 18.608 -196.764 9.921 1.00 30.83 ? 103 LYS E CD 1 ATOM 6468 C CE . LYS C 1 45 ? 17.884 -198.099 9.879 1.00 26.37 ? 103 LYS E CE 1 ATOM 6469 N NZ . LYS C 1 45 ? 16.414 -197.932 9.750 1.00 24.99 ? 103 LYS E NZ 1 ATOM 6470 N N . GLU C 1 46 ? 21.829 -193.477 10.345 1.00 30.34 ? 104 GLU E N 1 ATOM 6471 C CA . GLU C 1 46 ? 22.672 -192.344 10.004 1.00 37.04 ? 104 GLU E CA 1 ATOM 6472 C C . GLU C 1 46 ? 21.915 -191.332 9.154 1.00 31.41 ? 104 GLU E C 1 ATOM 6473 O O . GLU C 1 46 ? 21.272 -191.688 8.167 1.00 37.35 ? 104 GLU E O 1 ATOM 6474 C CB . GLU C 1 46 ? 23.926 -192.812 9.263 1.00 43.84 ? 104 GLU E CB 1 ATOM 6475 C CG . GLU C 1 46 ? 24.993 -191.736 9.109 1.00 64.73 ? 104 GLU E CG 1 ATOM 6476 C CD . GLU C 1 46 ? 26.301 -192.284 8.569 1.00 94.97 ? 104 GLU E CD 1 ATOM 6477 O OE1 . GLU C 1 46 ? 27.128 -192.757 9.376 1.00 87.57 ? 104 GLU E OE1 1 ATOM 6478 O OE2 . GLU C 1 46 ? 26.502 -192.240 7.337 1.00 79.37 ? 104 GLU E OE2 1 ATOM 6479 N N . VAL C 1 47 ? 21.991 -190.071 9.564 1.00 30.83 ? 105 VAL E N 1 ATOM 6480 C CA . VAL C 1 47 ? 21.484 -188.958 8.774 1.00 31.34 ? 105 VAL E CA 1 ATOM 6481 C C . VAL C 1 47 ? 22.549 -187.868 8.776 1.00 36.45 ? 105 VAL E C 1 ATOM 6482 O O . VAL C 1 47 ? 23.023 -187.456 9.839 1.00 35.21 ? 105 VAL E O 1 ATOM 6483 C CB . VAL C 1 47 ? 20.154 -188.408 9.327 1.00 31.81 ? 105 VAL E CB 1 ATOM 6484 C CG1 . VAL C 1 47 ? 19.611 -187.306 8.427 1.00 32.19 ? 105 VAL E CG1 1 ATOM 6485 C CG2 . VAL C 1 47 ? 19.133 -189.526 9.461 1.00 28.51 ? 105 VAL E CG2 1 ATOM 6486 N N . ASP C 1 48 ? 22.937 -187.427 7.583 1.00 33.43 ? 106 ASP E N 1 ATOM 6487 C CA . ASP C 1 48 ? 23.988 -186.425 7.428 1.00 35.35 ? 106 ASP E CA 1 ATOM 6488 C C . ASP C 1 48 ? 25.244 -186.820 8.199 1.00 36.07 ? 106 ASP E C 1 ATOM 6489 O O . ASP C 1 48 ? 25.875 -185.989 8.850 1.00 37.38 ? 106 ASP E O 1 ATOM 6490 C CB . ASP C 1 48 ? 23.492 -185.057 7.894 1.00 38.02 ? 106 ASP E CB 1 ATOM 6491 C CG . ASP C 1 48 ? 22.336 -184.547 7.063 1.00 56.34 ? 106 ASP E CG 1 ATOM 6492 O OD1 . ASP C 1 48 ? 22.477 -184.488 5.823 1.00 51.62 ? 106 ASP E OD1 1 ATOM 6493 O OD2 . ASP C 1 48 ? 21.282 -184.212 7.646 1.00 56.98 ? 106 ASP E OD2 1 ATOM 6494 N N . GLY C 1 49 ? 25.589 -188.101 8.131 1.00 33.99 ? 107 GLY E N 1 ATOM 6495 C CA . GLY C 1 49 ? 26.779 -188.608 8.789 1.00 45.73 ? 107 GLY E CA 1 ATOM 6496 C C . GLY C 1 49 ? 26.702 -188.647 10.307 1.00 43.23 ? 107 GLY E C 1 ATOM 6497 O O . GLY C 1 49 ? 27.716 -188.888 10.965 1.00 38.24 ? 107 GLY E O 1 ATOM 6498 N N . THR C 1 50 ? 25.516 -188.409 10.868 1.00 45.03 ? 108 THR E N 1 ATOM 6499 C CA . THR C 1 50 ? 25.326 -188.477 12.318 1.00 42.33 ? 108 THR E CA 1 ATOM 6500 C C . THR C 1 50 ? 24.356 -189.598 12.684 1.00 36.55 ? 108 THR E C 1 ATOM 6501 O O . THR C 1 50 ? 23.351 -189.804 12.005 1.00 25.72 ? 108 THR E O 1 ATOM 6502 C CB . THR C 1 50 ? 24.804 -187.141 12.881 1.00 42.15 ? 108 THR E CB 1 ATOM 6503 O OG1 . THR C 1 50 ? 25.678 -186.080 12.480 1.00 52.93 ? 108 THR E OG1 1 ATOM 6504 C CG2 . THR C 1 50 ? 24.736 -187.184 14.402 1.00 44.88 ? 108 THR E CG2 1 ATOM 6505 N N . LEU C 1 51 ? 24.664 -190.314 13.762 1.00 33.21 ? 109 LEU E N 1 ATOM 6506 C CA . LEU C 1 51 ? 23.847 -191.441 14.202 1.00 29.52 ? 109 LEU E CA 1 ATOM 6507 C C . LEU C 1 51 ? 22.699 -191.004 15.108 1.00 24.87 ? 109 LEU E C 1 ATOM 6508 O O . LEU C 1 51 ? 22.894 -190.230 16.047 1.00 28.39 ? 109 LEU E O 1 ATOM 6509 C CB . LEU C 1 51 ? 24.713 -192.468 14.932 1.00 35.72 ? 109 LEU E CB 1 ATOM 6510 C CG . LEU C 1 51 ? 25.589 -193.353 14.045 1.00 45.60 ? 109 LEU E CG 1 ATOM 6511 C CD1 . LEU C 1 51 ? 26.631 -194.073 14.882 1.00 54.29 ? 109 LEU E CD1 1 ATOM 6512 C CD2 . LEU C 1 51 ? 24.735 -194.354 13.284 1.00 38.86 ? 109 LEU E CD2 1 ATOM 6513 N N . TYR C 1 52 ? 21.505 -191.511 14.815 1.00 25.05 ? 110 TYR E N 1 ATOM 6514 C CA . TYR C 1 52 ? 20.319 -191.228 15.616 1.00 16.72 ? 110 TYR E CA 1 ATOM 6515 C C . TYR C 1 52 ? 19.606 -192.516 15.990 1.00 25.60 ? 110 TYR E C 1 ATOM 6516 O O . TYR C 1 52 ? 19.615 -193.485 15.231 1.00 27.62 ? 110 TYR E O 1 ATOM 6517 C CB . TYR C 1 52 ? 19.363 -190.302 14.859 1.00 20.96 ? 110 TYR E CB 1 ATOM 6518 C CG . TYR C 1 52 ? 19.968 -188.960 14.523 1.00 23.90 ? 110 TYR E CG 1 ATOM 6519 C CD1 . TYR C 1 52 ? 19.861 -187.890 15.400 1.00 25.40 ? 110 TYR E CD1 1 ATOM 6520 C CD2 . TYR C 1 52 ? 20.654 -188.765 13.332 1.00 30.04 ? 110 TYR E CD2 1 ATOM 6521 C CE1 . TYR C 1 52 ? 20.417 -186.661 15.099 1.00 28.60 ? 110 TYR E CE1 1 ATOM 6522 C CE2 . TYR C 1 52 ? 21.213 -187.541 13.022 1.00 25.33 ? 110 TYR E CE2 1 ATOM 6523 C CZ . TYR C 1 52 ? 21.092 -186.493 13.909 1.00 26.18 ? 110 TYR E CZ 1 ATOM 6524 O OH . TYR C 1 52 ? 21.647 -185.271 13.608 1.00 36.64 ? 110 TYR E OH 1 ATOM 6525 N N . ARG C 1 53 ? 18.987 -192.519 17.166 1.00 24.97 ? 111 ARG E N 1 ATOM 6526 C CA . ARG C 1 53 ? 18.231 -193.675 17.626 1.00 22.21 ? 111 ARG E CA 1 ATOM 6527 C C . ARG C 1 53 ? 16.851 -193.676 16.985 1.00 23.26 ? 111 ARG E C 1 ATOM 6528 O O . ARG C 1 53 ? 16.291 -192.617 16.696 1.00 30.10 ? 111 ARG E O 1 ATOM 6529 C CB . ARG C 1 53 ? 18.117 -193.676 19.150 1.00 22.97 ? 111 ARG E CB 1 ATOM 6530 C CG . ARG C 1 53 ? 19.454 -193.551 19.866 1.00 25.35 ? 111 ARG E CG 1 ATOM 6531 C CD . ARG C 1 53 ? 19.342 -193.950 21.329 1.00 28.91 ? 111 ARG E CD 1 ATOM 6532 N NE . ARG C 1 53 ? 19.061 -195.375 21.481 1.00 21.81 ? 111 ARG E NE 1 ATOM 6533 C CZ . ARG C 1 53 ? 18.767 -195.965 22.636 1.00 28.03 ? 111 ARG E CZ 1 ATOM 6534 N NH1 . ARG C 1 53 ? 18.707 -195.257 23.756 1.00 25.45 ? 111 ARG E NH1 1 ATOM 6535 N NH2 . ARG C 1 53 ? 18.526 -197.267 22.669 1.00 23.58 ? 111 ARG E NH2 1 ATOM 6536 N N . GLU C 1 54 ? 16.308 -194.871 16.769 1.00 18.92 ? 112 GLU E N 1 ATOM 6537 C CA . GLU C 1 54 ? 15.070 -195.034 16.019 1.00 22.04 ? 112 GLU E CA 1 ATOM 6538 C C . GLU C 1 54 ? 14.223 -196.163 16.597 1.00 22.61 ? 112 GLU E C 1 ATOM 6539 O O . GLU C 1 54 ? 14.736 -197.263 16.823 1.00 23.43 ? 112 GLU E O 1 ATOM 6540 C CB . GLU C 1 54 ? 15.381 -195.321 14.549 1.00 25.66 ? 112 GLU E CB 1 ATOM 6541 C CG . GLU C 1 54 ? 14.151 -195.434 13.647 1.00 23.40 ? 112 GLU E CG 1 ATOM 6542 C CD . GLU C 1 54 ? 14.463 -196.076 12.306 1.00 34.38 ? 112 GLU E CD 1 ATOM 6543 O OE1 . GLU C 1 54 ? 15.291 -197.011 12.268 1.00 29.93 ? 112 GLU E OE1 1 ATOM 6544 O OE2 . GLU C 1 54 ? 13.881 -195.652 11.285 1.00 24.66 ? 112 GLU E OE2 1 ATOM 6545 N N . PRO C 1 55 ? 12.924 -195.901 16.840 1.00 20.37 ? 113 PRO E N 1 ATOM 6546 C CA . PRO C 1 55 ? 12.031 -196.992 17.245 1.00 20.70 ? 113 PRO E CA 1 ATOM 6547 C C . PRO C 1 55 ? 12.004 -198.092 16.187 1.00 24.09 ? 113 PRO E C 1 ATOM 6548 O O . PRO C 1 55 ? 11.949 -197.777 14.997 1.00 21.73 ? 113 PRO E O 1 ATOM 6549 C CB . PRO C 1 55 ? 10.666 -196.306 17.375 1.00 13.76 ? 113 PRO E CB 1 ATOM 6550 C CG . PRO C 1 55 ? 10.978 -194.866 17.586 1.00 19.62 ? 113 PRO E CG 1 ATOM 6551 C CD . PRO C 1 55 ? 12.218 -194.608 16.794 1.00 18.31 ? 113 PRO E CD 1 ATOM 6552 N N . ALA C 1 56 ? 12.040 -199.352 16.616 1.00 22.22 ? 114 ALA E N 1 ATOM 6553 C CA . ALA C 1 56 ? 12.247 -200.474 15.702 1.00 25.23 ? 114 ALA E CA 1 ATOM 6554 C C . ALA C 1 56 ? 11.267 -201.622 15.931 1.00 24.78 ? 114 ALA E C 1 ATOM 6555 O O . ALA C 1 56 ? 11.243 -202.582 15.161 1.00 24.98 ? 114 ALA E O 1 ATOM 6556 C CB . ALA C 1 56 ? 13.674 -200.979 15.833 1.00 28.74 ? 114 ALA E CB 1 ATOM 6557 N N . GLY C 1 57 ? 10.462 -201.520 16.984 1.00 17.65 ? 115 GLY E N 1 ATOM 6558 C CA . GLY C 1 57 ? 9.531 -202.576 17.350 1.00 20.13 ? 115 GLY E CA 1 ATOM 6559 C C . GLY C 1 57 ? 8.569 -202.970 16.243 1.00 26.26 ? 115 GLY E C 1 ATOM 6560 O O . GLY C 1 57 ? 8.092 -202.121 15.489 1.00 28.08 ? 115 GLY E O 1 ATOM 6561 N N . LEU C 1 58 ? 8.270 -204.264 16.164 1.00 21.94 ? 116 LEU E N 1 ATOM 6562 C CA . LEU C 1 58 ? 7.462 -204.817 15.080 1.00 25.86 ? 116 LEU E CA 1 ATOM 6563 C C . LEU C 1 58 ? 6.000 -205.026 15.463 1.00 22.78 ? 116 LEU E C 1 ATOM 6564 O O . LEU C 1 58 ? 5.171 -205.317 14.603 1.00 27.59 ? 116 LEU E O 1 ATOM 6565 C CB . LEU C 1 58 ? 8.060 -206.147 14.615 1.00 25.65 ? 116 LEU E CB 1 ATOM 6566 C CG . LEU C 1 58 ? 8.905 -206.146 13.340 1.00 35.89 ? 116 LEU E CG 1 ATOM 6567 C CD1 . LEU C 1 58 ? 9.880 -204.984 13.306 1.00 32.85 ? 116 LEU E CD1 1 ATOM 6568 C CD2 . LEU C 1 58 ? 9.655 -207.466 13.228 1.00 32.86 ? 116 LEU E CD2 1 ATOM 6569 N N . CYS C 1 59 ? 5.685 -204.890 16.747 1.00 18.95 ? 117 CYS E N 1 ATOM 6570 C CA . CYS C 1 59 ? 4.307 -205.026 17.213 1.00 21.61 ? 117 CYS E CA 1 ATOM 6571 C C . CYS C 1 59 ? 3.725 -203.665 17.589 1.00 20.25 ? 117 CYS E C 1 ATOM 6572 O O . CYS C 1 59 ? 4.446 -202.801 18.090 1.00 15.61 ? 117 CYS E O 1 ATOM 6573 C CB . CYS C 1 59 ? 4.226 -205.975 18.413 1.00 28.94 ? 117 CYS E CB 1 ATOM 6574 S SG . CYS C 1 59 ? 4.431 -207.729 17.997 1.00 42.29 ? 117 CYS E SG 1 ATOM 6575 N N . PRO C 1 60 ? 2.420 -203.466 17.343 1.00 15.62 ? 118 PRO E N 1 ATOM 6576 C CA . PRO C 1 60 ? 1.758 -202.257 17.842 1.00 24.63 ? 118 PRO E CA 1 ATOM 6577 C C . PRO C 1 60 ? 1.526 -202.333 19.347 1.00 24.25 ? 118 PRO E C 1 ATOM 6578 O O . PRO C 1 60 ? 1.242 -203.415 19.865 1.00 21.77 ? 118 PRO E O 1 ATOM 6579 C CB . PRO C 1 60 ? 0.432 -202.240 17.078 1.00 19.28 ? 118 PRO E CB 1 ATOM 6580 C CG . PRO C 1 60 ? 0.156 -203.674 16.780 1.00 26.49 ? 118 PRO E CG 1 ATOM 6581 C CD . PRO C 1 60 ? 1.497 -204.320 16.571 1.00 19.07 ? 118 PRO E CD 1 ATOM 6582 N N . ILE C 1 61 ? 1.651 -201.199 20.030 1.00 19.39 ? 119 ILE E N 1 ATOM 6583 C CA . ILE C 1 61 ? 1.445 -201.127 21.474 1.00 11.96 ? 119 ILE E CA 1 ATOM 6584 C C . ILE C 1 61 ? 0.087 -200.495 21.762 1.00 18.67 ? 119 ILE E C 1 ATOM 6585 O O . ILE C 1 61 ? -0.091 -199.283 21.636 1.00 16.45 ? 119 ILE E O 1 ATOM 6586 C CB . ILE C 1 61 ? 2.568 -200.325 22.156 1.00 19.90 ? 119 ILE E CB 1 ATOM 6587 C CG1 . ILE C 1 61 ? 3.936 -200.807 21.656 1.00 15.24 ? 119 ILE E CG1 1 ATOM 6588 C CG2 . ILE C 1 61 ? 2.477 -200.445 23.670 1.00 16.19 ? 119 ILE E CG2 1 ATOM 6589 C CD1 . ILE C 1 61 ? 4.164 -202.313 21.792 1.00 23.80 ? 119 ILE E CD1 1 ATOM 6590 N N . TRP C 1 62 ? -0.870 -201.333 22.144 1.00 13.82 ? 120 TRP E N 1 ATOM 6591 C CA . TRP C 1 62 ? -2.248 -200.902 22.335 1.00 16.05 ? 120 TRP E CA 1 ATOM 6592 C C . TRP C 1 62 ? -2.418 -200.065 23.601 1.00 19.71 ? 120 TRP E C 1 ATOM 6593 O O . TRP C 1 62 ? -2.069 -200.502 24.698 1.00 18.10 ? 120 TRP E O 1 ATOM 6594 C CB . TRP C 1 62 ? -3.173 -202.121 22.389 1.00 17.60 ? 120 TRP E CB 1 ATOM 6595 C CG . TRP C 1 62 ? -3.236 -202.890 21.104 1.00 18.60 ? 120 TRP E CG 1 ATOM 6596 C CD1 . TRP C 1 62 ? -2.233 -203.615 20.531 1.00 20.22 ? 120 TRP E CD1 1 ATOM 6597 C CD2 . TRP C 1 62 ? -4.369 -203.018 20.237 1.00 15.18 ? 120 TRP E CD2 1 ATOM 6598 N NE1 . TRP C 1 62 ? -2.669 -204.182 19.357 1.00 21.34 ? 120 TRP E NE1 1 ATOM 6599 C CE2 . TRP C 1 62 ? -3.978 -203.830 19.155 1.00 22.28 ? 120 TRP E CE2 1 ATOM 6600 C CE3 . TRP C 1 62 ? -5.676 -202.521 20.270 1.00 21.92 ? 120 TRP E CE3 1 ATOM 6601 C CZ2 . TRP C 1 62 ? -4.846 -204.155 18.114 1.00 22.99 ? 120 TRP E CZ2 1 ATOM 6602 C CZ3 . TRP C 1 62 ? -6.536 -202.847 19.238 1.00 26.50 ? 120 TRP E CZ3 1 ATOM 6603 C CH2 . TRP C 1 62 ? -6.117 -203.656 18.175 1.00 21.43 ? 120 TRP E CH2 1 ATOM 6604 N N . GLY C 1 63 ? -2.960 -198.862 23.439 1.00 15.94 ? 121 GLY E N 1 ATOM 6605 C CA . GLY C 1 63 ? -3.276 -198.002 24.565 1.00 16.13 ? 121 GLY E CA 1 ATOM 6606 C C . GLY C 1 63 ? -2.125 -197.121 25.012 1.00 12.10 ? 121 GLY E C 1 ATOM 6607 O O . GLY C 1 63 ? -2.296 -196.274 25.889 1.00 15.19 ? 121 GLY E O 1 ATOM 6608 N N . LYS C 1 64 ? -0.953 -197.315 24.417 1.00 11.91 ? 122 LYS E N 1 ATOM 6609 C CA . LYS C 1 64 ? 0.222 -196.540 24.796 1.00 16.21 ? 122 LYS E CA 1 ATOM 6610 C C . LYS C 1 64 ? 0.100 -195.110 24.303 1.00 18.26 ? 122 LYS E C 1 ATOM 6611 O O . LYS C 1 64 ? -0.164 -194.878 23.122 1.00 17.18 ? 122 LYS E O 1 ATOM 6612 C CB . LYS C 1 64 ? 1.500 -197.169 24.235 1.00 11.92 ? 122 LYS E CB 1 ATOM 6613 C CG . LYS C 1 64 ? 2.722 -196.258 24.318 1.00 14.27 ? 122 LYS E CG 1 ATOM 6614 C CD . LYS C 1 64 ? 3.992 -196.946 23.853 1.00 14.35 ? 122 LYS E CD 1 ATOM 6615 C CE . LYS C 1 64 ? 5.133 -195.942 23.767 1.00 15.53 ? 122 LYS E CE 1 ATOM 6616 N NZ . LYS C 1 64 ? 6.459 -196.577 23.549 1.00 15.56 ? 122 LYS E NZ 1 ATOM 6617 N N . HIS C 1 65 ? 0.286 -194.153 25.207 1.00 18.06 ? 123 HIS E N 1 ATOM 6618 C CA . HIS C 1 65 ? 0.394 -192.755 24.800 1.00 17.65 ? 123 HIS E CA 1 ATOM 6619 C C . HIS C 1 65 ? 1.504 -192.066 25.582 1.00 19.00 ? 123 HIS E C 1 ATOM 6620 O O . HIS C 1 65 ? 1.964 -192.586 26.594 1.00 18.61 ? 123 HIS E O 1 ATOM 6621 C CB . HIS C 1 65 ? -0.940 -192.029 24.996 1.00 15.60 ? 123 HIS E CB 1 ATOM 6622 C CG . HIS C 1 65 ? -1.491 -192.136 26.383 1.00 19.09 ? 123 HIS E CG 1 ATOM 6623 N ND1 . HIS C 1 65 ? -2.008 -193.308 26.890 1.00 26.36 ? 123 HIS E ND1 1 ATOM 6624 C CD2 . HIS C 1 65 ? -1.611 -191.213 27.366 1.00 18.94 ? 123 HIS E CD2 1 ATOM 6625 C CE1 . HIS C 1 65 ? -2.419 -193.104 28.130 1.00 25.72 ? 123 HIS E CE1 1 ATOM 6626 N NE2 . HIS C 1 65 ? -2.190 -191.841 28.442 1.00 22.27 ? 123 HIS E NE2 1 ATOM 6627 N N . ILE C 1 66 ? 1.951 -190.910 25.101 1.00 17.93 ? 124 ILE E N 1 ATOM 6628 C CA . ILE C 1 66 ? 2.986 -190.157 25.800 1.00 11.62 ? 124 ILE E CA 1 ATOM 6629 C C . ILE C 1 66 ? 2.338 -189.048 26.615 1.00 16.78 ? 124 ILE E C 1 ATOM 6630 O O . ILE C 1 66 ? 1.753 -188.115 26.064 1.00 15.72 ? 124 ILE E O 1 ATOM 6631 C CB . ILE C 1 66 ? 4.023 -189.556 24.836 1.00 15.68 ? 124 ILE E CB 1 ATOM 6632 C CG1 . ILE C 1 66 ? 4.553 -190.627 23.876 1.00 17.12 ? 124 ILE E CG1 1 ATOM 6633 C CG2 . ILE C 1 66 ? 5.175 -188.924 25.618 1.00 18.58 ? 124 ILE E CG2 1 ATOM 6634 C CD1 . ILE C 1 66 ? 5.190 -191.829 24.562 1.00 16.76 ? 124 ILE E CD1 1 ATOM 6635 N N . GLU C 1 67 ? 2.430 -189.177 27.933 1.00 12.81 ? 125 GLU E N 1 ATOM 6636 C CA . GLU C 1 67 ? 1.910 -188.177 28.851 1.00 16.71 ? 125 GLU E CA 1 ATOM 6637 C C . GLU C 1 67 ? 2.911 -187.038 29.002 1.00 20.82 ? 125 GLU E C 1 ATOM 6638 O O . GLU C 1 67 ? 4.085 -187.263 29.328 1.00 18.92 ? 125 GLU E O 1 ATOM 6639 C CB . GLU C 1 67 ? 1.604 -188.806 30.210 1.00 14.06 ? 125 GLU E CB 1 ATOM 6640 C CG . GLU C 1 67 ? 1.006 -187.847 31.234 1.00 26.21 ? 125 GLU E CG 1 ATOM 6641 C CD . GLU C 1 67 ? 0.884 -188.472 32.615 1.00 49.82 ? 125 GLU E CD 1 ATOM 6642 O OE1 . GLU C 1 67 ? -0.246 -188.818 33.020 1.00 39.61 ? 125 GLU E OE1 1 ATOM 6643 O OE2 . GLU C 1 67 ? 1.922 -188.613 33.298 1.00 36.27 ? 125 GLU E OE2 1 ATOM 6644 N N . LEU C 1 68 ? 2.421 -185.825 28.753 1.00 15.33 ? 126 LEU E N 1 ATOM 6645 C CA . LEU C 1 68 ? 3.215 -184.598 28.818 1.00 18.34 ? 126 LEU E CA 1 ATOM 6646 C C . LEU C 1 68 ? 3.042 -183.888 30.158 1.00 18.70 ? 126 LEU E C 1 ATOM 6647 O O . LEU C 1 68 ? 2.034 -184.074 30.839 1.00 18.77 ? 126 LEU E O 1 ATOM 6648 C CB . LEU C 1 68 ? 2.811 -183.651 27.685 1.00 14.79 ? 126 LEU E CB 1 ATOM 6649 C CG . LEU C 1 68 ? 3.363 -183.928 26.285 1.00 25.86 ? 126 LEU E CG 1 ATOM 6650 C CD1 . LEU C 1 68 ? 3.357 -185.401 25.947 1.00 23.87 ? 126 LEU E CD1 1 ATOM 6651 C CD2 . LEU C 1 68 ? 2.566 -183.147 25.251 1.00 21.57 ? 126 LEU E CD2 1 ATOM 6652 N N . GLN C 1 69 ? 4.023 -183.065 30.520 1.00 18.02 ? 127 GLN E N 1 ATOM 6653 C CA . GLN C 1 69 ? 3.972 -182.299 31.763 1.00 19.87 ? 127 GLN E CA 1 ATOM 6654 C C . GLN C 1 69 ? 4.143 -180.802 31.501 1.00 19.65 ? 127 GLN E C 1 ATOM 6655 O O . GLN C 1 69 ? 4.983 -180.147 32.116 1.00 15.66 ? 127 GLN E O 1 ATOM 6656 C CB . GLN C 1 69 ? 5.050 -182.784 32.735 1.00 18.72 ? 127 GLN E CB 1 ATOM 6657 C CG . GLN C 1 69 ? 4.940 -184.254 33.117 1.00 25.88 ? 127 GLN E CG 1 ATOM 6658 C CD . GLN C 1 69 ? 4.212 -184.463 34.429 1.00 41.64 ? 127 GLN E CD 1 ATOM 6659 O OE1 . GLN C 1 69 ? 4.737 -185.094 35.346 1.00 71.30 ? 127 GLN E OE1 1 ATOM 6660 N NE2 . GLN C 1 69 ? 2.998 -183.934 34.525 1.00 39.00 ? 127 GLN E NE2 1 ATOM 6661 N N . GLN C 1 70 ? 3.348 -180.270 30.579 1.00 16.73 ? 128 GLN E N 1 ATOM 6662 C CA . GLN C 1 70 ? 3.312 -178.833 30.335 1.00 19.47 ? 128 GLN E CA 1 ATOM 6663 C C . GLN C 1 70 ? 2.461 -178.161 31.409 1.00 23.28 ? 128 GLN E C 1 ATOM 6664 O O . GLN C 1 70 ? 1.708 -178.837 32.111 1.00 18.42 ? 128 GLN E O 1 ATOM 6665 C CB . GLN C 1 70 ? 2.743 -178.532 28.947 1.00 17.09 ? 128 GLN E CB 1 ATOM 6666 C CG . GLN C 1 70 ? 3.571 -179.077 27.789 1.00 13.50 ? 128 GLN E CG 1 ATOM 6667 C CD . GLN C 1 70 ? 2.794 -179.110 26.485 1.00 11.13 ? 128 GLN E CD 1 ATOM 6668 O OE1 . GLN C 1 70 ? 1.588 -179.351 26.476 1.00 16.56 ? 128 GLN E OE1 1 ATOM 6669 N NE2 . GLN C 1 70 ? 3.482 -178.857 25.377 1.00 15.99 ? 128 GLN E NE2 1 ATOM 6670 N N . PRO C 1 71 ? 2.578 -176.830 31.550 1.00 26.72 ? 129 PRO E N 1 ATOM 6671 C CA . PRO C 1 71 ? 1.670 -176.123 32.462 1.00 22.26 ? 129 PRO E CA 1 ATOM 6672 C C . PRO C 1 71 ? 0.208 -176.362 32.087 1.00 24.52 ? 129 PRO E C 1 ATOM 6673 O O . PRO C 1 71 ? -0.099 -176.482 30.901 1.00 27.42 ? 129 PRO E O 1 ATOM 6674 C CB . PRO C 1 71 ? 2.063 -174.652 32.282 1.00 29.28 ? 129 PRO E CB 1 ATOM 6675 C CG . PRO C 1 71 ? 3.488 -174.699 31.838 1.00 23.00 ? 129 PRO E CG 1 ATOM 6676 C CD . PRO C 1 71 ? 3.601 -175.934 30.985 1.00 20.60 ? 129 PRO E CD 1 ATOM 6677 N N . ASP C 1 72 ? -0.671 -176.441 33.082 1.00 27.78 ? 130 ASP E N 1 ATOM 6678 C CA . ASP C 1 72 ? -2.079 -176.748 32.841 1.00 34.20 ? 130 ASP E CA 1 ATOM 6679 C C . ASP C 1 72 ? -2.896 -175.495 32.554 1.00 39.85 ? 130 ASP E C 1 ATOM 6680 O O . ASP C 1 72 ? -3.834 -175.172 33.282 1.00 54.30 ? 130 ASP E O 1 ATOM 6681 C CB . ASP C 1 72 ? -2.677 -177.492 34.040 1.00 42.79 ? 130 ASP E CB 1 ATOM 6682 C CG . ASP C 1 72 ? -2.165 -178.915 34.158 1.00 54.84 ? 130 ASP E CG 1 ATOM 6683 O OD1 . ASP C 1 72 ? -2.000 -179.581 33.113 1.00 63.09 ? 130 ASP E OD1 1 ATOM 6684 O OD2 . ASP C 1 72 ? -1.932 -179.369 35.297 1.00 77.20 ? 130 ASP E OD2 1 ATOM 6685 N N . ARG C 1 73 ? -2.534 -174.791 31.488 1.00 37.63 ? 131 ARG E N 1 ATOM 6686 C CA . ARG C 1 73 ? -3.309 -173.644 31.035 1.00 42.46 ? 131 ARG E CA 1 ATOM 6687 C C . ARG C 1 73 ? -2.889 -173.261 29.620 1.00 34.57 ? 131 ARG E C 1 ATOM 6688 O O . ARG C 1 73 ? -1.779 -173.588 29.198 1.00 36.16 ? 131 ARG E O 1 ATOM 6689 C CB . ARG C 1 73 ? -3.132 -172.454 31.984 1.00 38.07 ? 131 ARG E CB 1 ATOM 6690 C CG . ARG C 1 73 ? -1.762 -171.795 31.930 1.00 49.55 ? 131 ARG E CG 1 ATOM 6691 C CD . ARG C 1 73 ? -1.659 -170.672 32.950 1.00 64.16 ? 131 ARG E CD 1 ATOM 6692 N NE . ARG C 1 73 ? -0.330 -170.062 32.972 1.00 70.18 ? 131 ARG E NE 1 ATOM 6693 C CZ . ARG C 1 73 ? 0.712 -170.551 33.639 1.00 55.98 ? 131 ARG E CZ 1 ATOM 6694 N NH1 . ARG C 1 73 ? 0.595 -171.669 34.344 1.00 41.48 ? 131 ARG E NH1 1 ATOM 6695 N NH2 . ARG C 1 73 ? 1.879 -169.921 33.598 1.00 65.41 ? 131 ARG E NH2 1 ATOM 6696 N N . PRO C 1 74 ? -3.778 -172.574 28.880 1.00 33.18 ? 132 PRO E N 1 ATOM 6697 C CA . PRO C 1 74 ? -3.466 -172.085 27.531 1.00 43.43 ? 132 PRO E CA 1 ATOM 6698 C C . PRO C 1 74 ? -2.108 -171.385 27.460 1.00 28.89 ? 132 PRO E C 1 ATOM 6699 O O . PRO C 1 74 ? -1.748 -170.688 28.406 1.00 28.12 ? 132 PRO E O 1 ATOM 6700 C CB . PRO C 1 74 ? -4.602 -171.099 27.252 1.00 39.53 ? 132 PRO E CB 1 ATOM 6701 C CG . PRO C 1 74 ? -5.752 -171.638 28.023 1.00 43.59 ? 132 PRO E CG 1 ATOM 6702 C CD . PRO C 1 74 ? -5.178 -172.297 29.252 1.00 37.69 ? 132 PRO E CD 1 ATOM 6703 N N . PRO C 1 75 ? -1.366 -171.555 26.354 1.00 25.06 ? 133 PRO E N 1 ATOM 6704 C CA . PRO C 1 75 ? -1.710 -172.289 25.130 1.00 24.13 ? 133 PRO E CA 1 ATOM 6705 C C . PRO C 1 75 ? -1.424 -173.795 25.185 1.00 30.54 ? 133 PRO E C 1 ATOM 6706 O O . PRO C 1 75 ? -1.558 -174.466 24.164 1.00 23.46 ? 133 PRO E O 1 ATOM 6707 C CB . PRO C 1 75 ? -0.821 -171.623 24.082 1.00 28.62 ? 133 PRO E CB 1 ATOM 6708 C CG . PRO C 1 75 ? 0.405 -171.255 24.841 1.00 26.16 ? 133 PRO E CG 1 ATOM 6709 C CD . PRO C 1 75 ? -0.057 -170.888 26.233 1.00 22.60 ? 133 PRO E CD 1 ATOM 6710 N N . TYR C 1 76 ? -1.041 -174.315 26.347 1.00 20.79 ? 134 TYR E N 1 ATOM 6711 C CA . TYR C 1 76 ? -0.674 -175.726 26.461 1.00 25.08 ? 134 TYR E CA 1 ATOM 6712 C C . TYR C 1 76 ? -1.904 -176.627 26.556 1.00 21.79 ? 134 TYR E C 1 ATOM 6713 O O . TYR C 1 76 ? -2.857 -176.312 27.269 1.00 27.03 ? 134 TYR E O 1 ATOM 6714 C CB . TYR C 1 76 ? 0.224 -175.942 27.679 1.00 12.78 ? 134 TYR E CB 1 ATOM 6715 C CG . TYR C 1 76 ? 1.481 -175.102 27.659 1.00 16.57 ? 134 TYR E CG 1 ATOM 6716 C CD1 . TYR C 1 76 ? 2.588 -175.485 26.912 1.00 13.70 ? 134 TYR E CD1 1 ATOM 6717 C CD2 . TYR C 1 76 ? 1.559 -173.924 28.388 1.00 16.17 ? 134 TYR E CD2 1 ATOM 6718 C CE1 . TYR C 1 76 ? 3.738 -174.714 26.892 1.00 13.19 ? 134 TYR E CE1 1 ATOM 6719 C CE2 . TYR C 1 76 ? 2.701 -173.150 28.375 1.00 19.10 ? 134 TYR E CE2 1 ATOM 6720 C CZ . TYR C 1 76 ? 3.786 -173.546 27.629 1.00 18.70 ? 134 TYR E CZ 1 ATOM 6721 O OH . TYR C 1 76 ? 4.918 -172.766 27.626 1.00 16.79 ? 134 TYR E OH 1 ATOM 6722 N N . ARG C 1 77 ? -1.871 -177.745 25.833 1.00 22.75 ? 135 ARG E N 1 ATOM 6723 C CA . ARG C 1 77 ? -2.977 -178.705 25.816 1.00 24.62 ? 135 ARG E CA 1 ATOM 6724 C C . ARG C 1 77 ? -2.625 -180.028 26.501 1.00 24.91 ? 135 ARG E C 1 ATOM 6725 O O . ARG C 1 77 ? -3.515 -180.824 26.804 1.00 25.56 ? 135 ARG E O 1 ATOM 6726 C CB . ARG C 1 77 ? -3.413 -178.989 24.374 1.00 27.02 ? 135 ARG E CB 1 ATOM 6727 C CG . ARG C 1 77 ? -3.810 -177.755 23.570 1.00 38.99 ? 135 ARG E CG 1 ATOM 6728 C CD . ARG C 1 77 ? -5.151 -177.186 24.006 1.00 49.27 ? 135 ARG E CD 1 ATOM 6729 N NE . ARG C 1 77 ? -6.256 -177.689 23.186 1.00 73.50 ? 135 ARG E NE 1 ATOM 6730 C CZ . ARG C 1 77 ? -7.314 -178.361 23.640 1.00 84.95 ? 135 ARG E CZ 1 ATOM 6731 N NH1 . ARG C 1 77 ? -7.456 -178.636 24.932 1.00 79.69 ? 135 ARG E NH1 1 ATOM 6732 N NH2 . ARG C 1 77 ? -8.248 -178.762 22.788 1.00 81.43 ? 135 ARG E NH2 1 ATOM 6733 N N . ASN C 1 78 ? -1.336 -180.259 26.744 1.00 22.58 ? 136 ASN E N 1 ATOM 6734 C CA . ASN C 1 78 ? -0.858 -181.533 27.292 1.00 23.86 ? 136 ASN E CA 1 ATOM 6735 C C . ASN C 1 78 ? -1.397 -182.719 26.493 1.00 19.22 ? 136 ASN E C 1 ATOM 6736 O O . ASN C 1 78 ? -2.005 -183.642 27.036 1.00 21.95 ? 136 ASN E O 1 ATOM 6737 C CB . ASN C 1 78 ? -1.236 -181.663 28.769 1.00 19.99 ? 136 ASN E CB 1 ATOM 6738 C CG . ASN C 1 78 ? -0.256 -180.951 29.681 1.00 24.32 ? 136 ASN E CG 1 ATOM 6739 O OD1 . ASN C 1 78 ? 0.906 -181.346 29.789 1.00 21.60 ? 136 ASN E OD1 1 ATOM 6740 N ND2 . ASN C 1 78 ? -0.717 -179.897 30.343 1.00 33.27 ? 136 ASN E ND2 1 ATOM 6741 N N . ASN C 1 79 ? -1.161 -182.669 25.189 1.00 17.66 ? 137 ASN E N 1 ATOM 6742 C CA . ASN C 1 79 ? -1.622 -183.688 24.263 1.00 17.57 ? 137 ASN E CA 1 ATOM 6743 C C . ASN C 1 79 ? -0.547 -183.912 23.211 1.00 16.63 ? 137 ASN E C 1 ATOM 6744 O O . ASN C 1 79 ? -0.281 -183.034 22.389 1.00 15.94 ? 137 ASN E O 1 ATOM 6745 C CB . ASN C 1 79 ? -2.942 -183.261 23.620 1.00 17.91 ? 137 ASN E CB 1 ATOM 6746 C CG . ASN C 1 79 ? -3.508 -184.306 22.677 1.00 29.06 ? 137 ASN E CG 1 ATOM 6747 O OD1 . ASN C 1 79 ? -2.879 -185.328 22.404 1.00 22.85 ? 137 ASN E OD1 1 ATOM 6748 N ND2 . ASN C 1 79 ? -4.704 -184.045 22.165 1.00 30.24 ? 137 ASN E ND2 1 ATOM 6749 N N . PHE C 1 80 ? 0.076 -185.085 23.242 1.00 11.84 ? 138 PHE E N 1 ATOM 6750 C CA . PHE C 1 80 ? 1.226 -185.344 22.384 1.00 14.22 ? 138 PHE E CA 1 ATOM 6751 C C . PHE C 1 80 ? 0.826 -185.472 20.912 1.00 11.85 ? 138 PHE E C 1 ATOM 6752 O O . PHE C 1 80 ? 1.686 -185.445 20.034 1.00 15.73 ? 138 PHE E O 1 ATOM 6753 C CB . PHE C 1 80 ? 1.983 -186.594 22.865 1.00 15.12 ? 138 PHE E CB 1 ATOM 6754 C CG . PHE C 1 80 ? 1.360 -187.908 22.457 1.00 10.49 ? 138 PHE E CG 1 ATOM 6755 C CD1 . PHE C 1 80 ? 0.052 -188.218 22.791 1.00 13.41 ? 138 PHE E CD1 1 ATOM 6756 C CD2 . PHE C 1 80 ? 2.114 -188.855 21.779 1.00 18.26 ? 138 PHE E CD2 1 ATOM 6757 C CE1 . PHE C 1 80 ? -0.502 -189.440 22.425 1.00 13.32 ? 138 PHE E CE1 1 ATOM 6758 C CE2 . PHE C 1 80 ? 1.567 -190.073 21.414 1.00 16.36 ? 138 PHE E CE2 1 ATOM 6759 C CZ . PHE C 1 80 ? 0.259 -190.365 21.737 1.00 15.08 ? 138 PHE E CZ 1 ATOM 6760 N N . LEU C 1 81 ? -0.473 -185.570 20.639 1.00 13.72 ? 139 LEU E N 1 ATOM 6761 C CA . LEU C 1 81 ? -0.952 -185.629 19.258 1.00 20.76 ? 139 LEU E CA 1 ATOM 6762 C C . LEU C 1 81 ? -1.143 -184.235 18.651 1.00 21.40 ? 139 LEU E C 1 ATOM 6763 O O . LEU C 1 81 ? -1.474 -184.109 17.472 1.00 19.57 ? 139 LEU E O 1 ATOM 6764 C CB . LEU C 1 81 ? -2.264 -186.415 19.178 1.00 17.64 ? 139 LEU E CB 1 ATOM 6765 C CG . LEU C 1 81 ? -2.180 -187.916 19.487 1.00 19.03 ? 139 LEU E CG 1 ATOM 6766 C CD1 . LEU C 1 81 ? -3.522 -188.571 19.232 1.00 21.67 ? 139 LEU E CD1 1 ATOM 6767 C CD2 . LEU C 1 81 ? -1.097 -188.610 18.669 1.00 18.46 ? 139 LEU E CD2 1 ATOM 6768 N N . GLU C 1 82 ? -0.935 -183.193 19.450 1.00 18.32 ? 140 GLU E N 1 ATOM 6769 C CA . GLU C 1 82 ? -0.936 -181.830 18.927 1.00 18.72 ? 140 GLU E CA 1 ATOM 6770 C C . GLU C 1 82 ? 0.288 -181.632 18.050 1.00 13.39 ? 140 GLU E C 1 ATOM 6771 O O . GLU C 1 82 ? 1.320 -182.269 18.270 1.00 12.38 ? 140 GLU E O 1 ATOM 6772 C CB . GLU C 1 82 ? -0.936 -180.801 20.059 1.00 17.44 ? 140 GLU E CB 1 ATOM 6773 C CG . GLU C 1 82 ? -2.197 -180.792 20.904 0.75 23.21 ? 140 GLU E CG 1 ATOM 6774 C CD . GLU C 1 82 ? -3.362 -180.079 20.239 0.44 32.35 ? 140 GLU E CD 1 ATOM 6775 O OE1 . GLU C 1 82 ? -4.521 -180.432 20.546 0.77 39.79 ? 140 GLU E OE1 1 ATOM 6776 O OE2 . GLU C 1 82 ? -3.128 -179.162 19.423 0.56 31.56 ? 140 GLU E OE2 1 ATOM 6777 N N . ASP C 1 83 ? 0.172 -180.751 17.061 1.00 16.53 ? 141 ASP E N 1 ATOM 6778 C CA . ASP C 1 83 ? 1.290 -180.422 16.184 1.00 15.11 ? 141 ASP E CA 1 ATOM 6779 C C . ASP C 1 83 ? 2.516 -179.986 16.967 1.00 13.47 ? 141 ASP E C 1 ATOM 6780 O O . ASP C 1 83 ? 2.400 -179.343 18.010 1.00 13.80 ? 141 ASP E O 1 ATOM 6781 C CB . ASP C 1 83 ? 0.909 -179.301 15.212 1.00 24.58 ? 141 ASP E CB 1 ATOM 6782 C CG . ASP C 1 83 ? -0.084 -179.743 14.155 1.00 27.59 ? 141 ASP E CG 1 ATOM 6783 O OD1 . ASP C 1 83 ? -0.139 -180.950 13.840 1.00 29.01 ? 141 ASP E OD1 1 ATOM 6784 O OD2 . ASP C 1 83 ? -0.805 -178.871 13.628 1.00 32.10 ? 141 ASP E OD2 1 ATOM 6785 N N . VAL C 1 84 ? 3.691 -180.331 16.450 1.00 15.20 ? 142 VAL E N 1 ATOM 6786 C CA . VAL C 1 84 ? 4.926 -179.764 16.961 1.00 13.53 ? 142 VAL E CA 1 ATOM 6787 C C . VAL C 1 84 ? 4.846 -178.250 16.802 1.00 22.93 ? 142 VAL E C 1 ATOM 6788 O O . VAL C 1 84 ? 4.241 -177.756 15.852 1.00 18.68 ? 142 VAL E O 1 ATOM 6789 C CB . VAL C 1 84 ? 6.173 -180.298 16.228 1.00 18.85 ? 142 VAL E CB 1 ATOM 6790 C CG1 . VAL C 1 84 ? 6.401 -181.764 16.563 1.00 19.52 ? 142 VAL E CG1 1 ATOM 6791 C CG2 . VAL C 1 84 ? 6.047 -180.093 14.725 1.00 19.44 ? 142 VAL E CG2 1 ATOM 6792 N N . PRO C 1 85 ? 5.454 -177.505 17.734 1.00 23.47 ? 143 PRO E N 1 ATOM 6793 C CA . PRO C 1 85 ? 5.322 -176.046 17.714 1.00 19.45 ? 143 PRO E CA 1 ATOM 6794 C C . PRO C 1 85 ? 6.222 -175.378 16.681 1.00 17.83 ? 143 PRO E C 1 ATOM 6795 O O . PRO C 1 85 ? 7.328 -175.851 16.426 1.00 18.78 ? 143 PRO E O 1 ATOM 6796 C CB . PRO C 1 85 ? 5.742 -175.649 19.128 1.00 17.87 ? 143 PRO E CB 1 ATOM 6797 C CG . PRO C 1 85 ? 6.757 -176.683 19.498 1.00 20.62 ? 143 PRO E CG 1 ATOM 6798 C CD . PRO C 1 85 ? 6.284 -177.966 18.862 1.00 21.16 ? 143 PRO E CD 1 ATOM 6799 N N . THR C 1 86 ? 5.746 -174.288 16.093 1.00 17.73 ? 144 THR E N 1 ATOM 6800 C CA . THR C 1 86 ? 6.600 -173.444 15.271 1.00 18.89 ? 144 THR E CA 1 ATOM 6801 C C . THR C 1 86 ? 7.426 -172.563 16.195 1.00 18.56 ? 144 THR E C 1 ATOM 6802 O O . THR C 1 86 ? 7.109 -172.433 17.378 1.00 20.00 ? 144 THR E O 1 ATOM 6803 C CB . THR C 1 86 ? 5.795 -172.560 14.318 1.00 25.53 ? 144 THR E CB 1 ATOM 6804 O OG1 . THR C 1 86 ? 4.982 -171.660 15.080 1.00 20.96 ? 144 THR E OG1 1 ATOM 6805 C CG2 . THR C 1 86 ? 4.911 -173.408 13.413 1.00 24.94 ? 144 THR E CG2 1 ATOM 6806 N N . GLU C 1 87 ? 8.480 -171.956 15.662 1.00 21.63 ? 145 GLU E N 1 ATOM 6807 C CA . GLU C 1 87 ? 9.318 -171.070 16.459 1.00 27.61 ? 145 GLU E CA 1 ATOM 6808 C C . GLU C 1 87 ? 8.501 -169.888 16.977 1.00 29.58 ? 145 GLU E C 1 ATOM 6809 O O . GLU C 1 87 ? 8.662 -169.462 18.121 1.00 34.35 ? 145 GLU E O 1 ATOM 6810 C CB . GLU C 1 87 ? 10.513 -170.581 15.637 1.00 32.93 ? 145 GLU E CB 1 ATOM 6811 C CG . GLU C 1 87 ? 11.434 -169.612 16.369 1.00 53.25 ? 145 GLU E CG 1 ATOM 6812 C CD . GLU C 1 87 ? 11.989 -170.176 17.668 1.00 81.12 ? 145 GLU E CD 1 ATOM 6813 O OE1 . GLU C 1 87 ? 12.354 -169.377 18.559 1.00 61.80 ? 145 GLU E OE1 1 ATOM 6814 O OE2 . GLU C 1 87 ? 12.070 -171.415 17.800 1.00 68.68 ? 145 GLU E OE2 1 ATOM 6815 N N . LYS C 1 88 ? 7.610 -169.379 16.134 1.00 23.32 ? 146 LYS E N 1 ATOM 6816 C CA . LYS C 1 88 ? 6.759 -168.248 16.492 1.00 25.32 ? 146 LYS E CA 1 ATOM 6817 C C . LYS C 1 88 ? 5.853 -168.574 17.680 1.00 27.89 ? 146 LYS E C 1 ATOM 6818 O O . LYS C 1 88 ? 5.749 -167.793 18.628 1.00 27.31 ? 146 LYS E O 1 ATOM 6819 C CB . LYS C 1 88 ? 5.920 -167.829 15.284 1.00 31.01 ? 146 LYS E CB 1 ATOM 6820 C CG . LYS C 1 88 ? 5.048 -166.608 15.509 1.00 40.81 ? 146 LYS E CG 1 ATOM 6821 C CD . LYS C 1 88 ? 4.677 -165.961 14.181 1.00 49.69 ? 146 LYS E CD 1 ATOM 6822 C CE . LYS C 1 88 ? 3.745 -164.773 14.367 1.00 55.77 ? 146 LYS E CE 1 ATOM 6823 N NZ . LYS C 1 88 ? 2.309 -165.165 14.298 1.00 56.36 ? 146 LYS E NZ 1 ATOM 6824 N N . GLU C 1 89 ? 5.202 -169.732 17.623 1.00 25.46 ? 147 GLU E N 1 ATOM 6825 C CA . GLU C 1 89 ? 4.352 -170.194 18.716 1.00 28.61 ? 147 GLU E CA 1 ATOM 6826 C C . GLU C 1 89 ? 5.162 -170.354 20.001 1.00 13.01 ? 147 GLU E C 1 ATOM 6827 O O . GLU C 1 89 ? 4.696 -170.023 21.094 1.00 25.94 ? 147 GLU E O 1 ATOM 6828 C CB . GLU C 1 89 ? 3.680 -171.518 18.339 1.00 26.57 ? 147 GLU E CB 1 ATOM 6829 C CG . GLU C 1 89 ? 2.638 -171.378 17.232 1.00 42.85 ? 147 GLU E CG 1 ATOM 6830 C CD . GLU C 1 89 ? 2.167 -172.711 16.669 1.00 43.54 ? 147 GLU E CD 1 ATOM 6831 O OE1 . GLU C 1 89 ? 1.116 -172.727 15.992 1.00 39.73 ? 147 GLU E OE1 1 ATOM 6832 O OE2 . GLU C 1 89 ? 2.844 -173.738 16.890 1.00 26.68 ? 147 GLU E OE2 1 ATOM 6833 N N . TYR C 1 90 ? 6.383 -170.858 19.854 1.00 16.18 ? 148 TYR E N 1 ATOM 6834 C CA . TYR C 1 90 ? 7.279 -171.051 20.986 1.00 21.33 ? 148 TYR E CA 1 ATOM 6835 C C . TYR C 1 90 ? 7.638 -169.700 21.601 1.00 25.38 ? 148 TYR E C 1 ATOM 6836 O O . TYR C 1 90 ? 7.620 -169.534 22.822 1.00 23.66 ? 148 TYR E O 1 ATOM 6837 C CB . TYR C 1 90 ? 8.540 -171.801 20.544 1.00 19.69 ? 148 TYR E CB 1 ATOM 6838 C CG . TYR C 1 90 ? 9.544 -172.059 21.649 1.00 21.15 ? 148 TYR E CG 1 ATOM 6839 C CD1 . TYR C 1 90 ? 9.139 -172.207 22.968 1.00 15.65 ? 148 TYR E CD1 1 ATOM 6840 C CD2 . TYR C 1 90 ? 10.901 -172.150 21.369 1.00 21.73 ? 148 TYR E CD2 1 ATOM 6841 C CE1 . TYR C 1 90 ? 10.056 -172.442 23.978 1.00 24.48 ? 148 TYR E CE1 1 ATOM 6842 C CE2 . TYR C 1 90 ? 11.825 -172.383 22.371 1.00 20.08 ? 148 TYR E CE2 1 ATOM 6843 C CZ . TYR C 1 90 ? 11.397 -172.528 23.673 1.00 24.26 ? 148 TYR E CZ 1 ATOM 6844 O OH . TYR C 1 90 ? 12.313 -172.758 24.675 1.00 25.86 ? 148 TYR E OH 1 ATOM 6845 N N . LYS C 1 91 ? 7.957 -168.733 20.746 1.00 23.66 ? 149 LYS E N 1 ATOM 6846 C CA . LYS C 1 91 ? 8.221 -167.373 21.203 1.00 26.56 ? 149 LYS E CA 1 ATOM 6847 C C . LYS C 1 91 ? 6.994 -166.779 21.879 1.00 29.32 ? 149 LYS E C 1 ATOM 6848 O O . LYS C 1 91 ? 7.104 -166.093 22.894 1.00 30.34 ? 149 LYS E O 1 ATOM 6849 C CB . LYS C 1 91 ? 8.655 -166.486 20.035 1.00 29.34 ? 149 LYS E CB 1 ATOM 6850 C CG . LYS C 1 91 ? 10.045 -166.806 19.517 1.00 36.85 ? 149 LYS E CG 1 ATOM 6851 C CD . LYS C 1 91 ? 10.400 -165.962 18.305 1.00 56.28 ? 149 LYS E CD 1 ATOM 6852 C CE . LYS C 1 91 ? 11.826 -166.226 17.842 1.00 71.52 ? 149 LYS E CE 1 ATOM 6853 N NZ . LYS C 1 91 ? 12.244 -165.325 16.732 1.00 60.33 ? 149 LYS E NZ 1 ATOM 6854 N N . GLN C 1 92 ? 5.821 -167.049 21.318 1.00 25.33 ? 150 GLN E N 1 ATOM 6855 C CA . GLN C 1 92 ? 4.583 -166.524 21.880 1.00 23.24 ? 150 GLN E CA 1 ATOM 6856 C C . GLN C 1 92 ? 4.217 -167.167 23.217 1.00 35.76 ? 150 GLN E C 1 ATOM 6857 O O . GLN C 1 92 ? 3.676 -166.496 24.097 1.00 23.34 ? 150 GLN E O 1 ATOM 6858 C CB . GLN C 1 92 ? 3.436 -166.702 20.883 1.00 32.84 ? 150 GLN E CB 1 ATOM 6859 C CG . GLN C 1 92 ? 3.516 -165.741 19.699 1.00 55.59 ? 150 GLN E CG 1 ATOM 6860 C CD . GLN C 1 92 ? 2.465 -166.012 18.639 1.00 68.26 ? 150 GLN E CD 1 ATOM 6861 O OE1 . GLN C 1 92 ? 2.013 -167.145 18.467 1.00 58.25 ? 150 GLN E OE1 1 ATOM 6862 N NE2 . GLN C 1 92 ? 2.069 -164.967 17.922 1.00 55.96 ? 150 GLN E NE2 1 ATOM 6863 N N . SER C 1 93 ? 4.499 -168.457 23.378 1.00 21.03 ? 151 SER E N 1 ATOM 6864 C CA . SER C 1 93 ? 4.176 -169.137 24.631 1.00 23.76 ? 151 SER E CA 1 ATOM 6865 C C . SER C 1 93 ? 5.194 -168.855 25.731 1.00 18.38 ? 151 SER E C 1 ATOM 6866 O O . SER C 1 93 ? 4.829 -168.670 26.892 1.00 21.65 ? 151 SER E O 1 ATOM 6867 C CB . SER C 1 93 ? 4.081 -170.651 24.416 1.00 18.42 ? 151 SER E CB 1 ATOM 6868 O OG . SER C 1 93 ? 5.338 -171.201 24.066 1.00 20.64 ? 151 SER E OG 1 ATOM 6869 N N . GLY C 1 94 ? 6.468 -168.828 25.360 1.00 20.53 ? 152 GLY E N 1 ATOM 6870 C CA . GLY C 1 94 ? 7.544 -168.850 26.332 1.00 27.12 ? 152 GLY E CA 1 ATOM 6871 C C . GLY C 1 94 ? 7.753 -170.278 26.801 1.00 24.23 ? 152 GLY E C 1 ATOM 6872 O O . GLY C 1 94 ? 7.007 -171.173 26.407 1.00 25.51 ? 152 GLY E O 1 ATOM 6873 N N . ASN C 1 95 ? 8.759 -170.495 27.642 1.00 23.47 ? 153 ASN E N 1 ATOM 6874 C CA . ASN C 1 95 ? 9.090 -171.837 28.116 1.00 23.57 ? 153 ASN E CA 1 ATOM 6875 C C . ASN C 1 95 ? 7.963 -172.492 28.919 1.00 17.30 ? 153 ASN E C 1 ATOM 6876 O O . ASN C 1 95 ? 7.267 -171.816 29.675 1.00 21.44 ? 153 ASN E O 1 ATOM 6877 C CB . ASN C 1 95 ? 10.354 -171.791 28.976 1.00 23.13 ? 153 ASN E CB 1 ATOM 6878 C CG . ASN C 1 95 ? 11.627 -171.793 28.153 1.00 19.66 ? 153 ASN E CG 1 ATOM 6879 O OD1 . ASN C 1 95 ? 11.591 -171.849 26.925 1.00 27.07 ? 153 ASN E OD1 1 ATOM 6880 N ND2 . ASN C 1 95 ? 12.767 -171.727 28.832 1.00 37.54 ? 153 ASN E ND2 1 ATOM 6881 N N . PRO C 1 96 ? 7.777 -173.815 28.760 1.00 19.70 ? 154 PRO E N 1 ATOM 6882 C CA . PRO C 1 96 ? 8.468 -174.728 27.844 1.00 18.37 ? 154 PRO E CA 1 ATOM 6883 C C . PRO C 1 96 ? 7.807 -174.771 26.471 1.00 17.27 ? 154 PRO E C 1 ATOM 6884 O O . PRO C 1 96 ? 6.815 -174.075 26.251 1.00 16.84 ? 154 PRO E O 1 ATOM 6885 C CB . PRO C 1 96 ? 8.337 -176.076 28.546 1.00 15.77 ? 154 PRO E CB 1 ATOM 6886 C CG . PRO C 1 96 ? 7.008 -175.994 29.191 1.00 21.34 ? 154 PRO E CG 1 ATOM 6887 C CD . PRO C 1 96 ? 6.853 -174.552 29.641 1.00 16.18 ? 154 PRO E CD 1 ATOM 6888 N N . LEU C 1 97 ? 8.354 -175.585 25.573 1.00 14.87 ? 155 LEU E N 1 ATOM 6889 C CA . LEU C 1 97 ? 7.759 -175.821 24.261 1.00 16.95 ? 155 LEU E CA 1 ATOM 6890 C C . LEU C 1 97 ? 6.268 -176.126 24.369 1.00 12.68 ? 155 LEU E C 1 ATOM 6891 O O . LEU C 1 97 ? 5.871 -176.973 25.163 1.00 14.31 ? 155 LEU E O 1 ATOM 6892 C CB . LEU C 1 97 ? 8.453 -176.989 23.558 1.00 14.98 ? 155 LEU E CB 1 ATOM 6893 C CG . LEU C 1 97 ? 9.874 -176.771 23.047 1.00 19.79 ? 155 LEU E CG 1 ATOM 6894 C CD1 . LEU C 1 97 ? 10.534 -178.109 22.757 1.00 25.70 ? 155 LEU E CD1 1 ATOM 6895 C CD2 . LEU C 1 97 ? 9.866 -175.902 21.802 1.00 27.06 ? 155 LEU E CD2 1 ATOM 6896 N N . PRO C 1 98 ? 5.434 -175.431 23.581 1.00 13.97 ? 156 PRO E N 1 ATOM 6897 C CA . PRO C 1 98 ? 4.018 -175.801 23.528 1.00 13.53 ? 156 PRO E CA 1 ATOM 6898 C C . PRO C 1 98 ? 3.772 -176.881 22.476 1.00 12.92 ? 156 PRO E C 1 ATOM 6899 O O . PRO C 1 98 ? 4.732 -177.428 21.934 1.00 16.39 ? 156 PRO E O 1 ATOM 6900 C CB . PRO C 1 98 ? 3.335 -174.488 23.153 1.00 18.58 ? 156 PRO E CB 1 ATOM 6901 C CG . PRO C 1 98 ? 4.339 -173.801 22.285 1.00 14.97 ? 156 PRO E CG 1 ATOM 6902 C CD . PRO C 1 98 ? 5.707 -174.214 22.796 1.00 16.27 ? 156 PRO E CD 1 ATOM 6903 N N . GLY C 1 99 ? 2.509 -177.182 22.197 1.00 16.97 ? 157 GLY E N 1 ATOM 6904 C CA . GLY C 1 99 ? 2.170 -178.164 21.184 1.00 14.91 ? 157 GLY E CA 1 ATOM 6905 C C . GLY C 1 99 ? 2.458 -179.588 21.625 1.00 19.18 ? 157 GLY E C 1 ATOM 6906 O O . GLY C 1 99 ? 2.516 -179.878 22.822 1.00 15.21 ? 157 GLY E O 1 ATOM 6907 N N . GLY C 1 100 ? 2.640 -180.476 20.650 1.00 19.14 ? 158 GLY E N 1 ATOM 6908 C CA . GLY C 1 100 ? 2.847 -181.888 20.920 1.00 14.40 ? 158 GLY E CA 1 ATOM 6909 C C . GLY C 1 100 ? 3.919 -182.502 20.043 1.00 14.47 ? 158 GLY E C 1 ATOM 6910 O O . GLY C 1 100 ? 4.906 -181.846 19.706 1.00 10.62 ? 158 GLY E O 1 ATOM 6911 N N . PHE C 1 101 ? 3.717 -183.764 19.671 1.00 12.29 ? 159 PHE E N 1 ATOM 6912 C CA . PHE C 1 101 ? 4.704 -184.525 18.908 1.00 12.57 ? 159 PHE E CA 1 ATOM 6913 C C . PHE C 1 101 ? 4.325 -184.697 17.437 1.00 16.58 ? 159 PHE E C 1 ATOM 6914 O O . PHE C 1 101 ? 5.117 -185.211 16.649 1.00 13.41 ? 159 PHE E O 1 ATOM 6915 C CB . PHE C 1 101 ? 4.897 -185.920 19.518 1.00 15.87 ? 159 PHE E CB 1 ATOM 6916 C CG . PHE C 1 101 ? 5.601 -185.931 20.850 1.00 13.46 ? 159 PHE E CG 1 ATOM 6917 C CD1 . PHE C 1 101 ? 5.906 -184.757 21.523 1.00 16.88 ? 159 PHE E CD1 1 ATOM 6918 C CD2 . PHE C 1 101 ? 5.969 -187.138 21.423 1.00 19.58 ? 159 PHE E CD2 1 ATOM 6919 C CE1 . PHE C 1 101 ? 6.557 -184.792 22.742 1.00 17.52 ? 159 PHE E CE1 1 ATOM 6920 C CE2 . PHE C 1 101 ? 6.619 -187.179 22.638 1.00 17.92 ? 159 PHE E CE2 1 ATOM 6921 C CZ . PHE C 1 101 ? 6.913 -186.006 23.300 1.00 14.55 ? 159 PHE E CZ 1 ATOM 6922 N N . ASN C 1 102 ? 3.114 -184.293 17.070 1.00 12.61 ? 160 ASN E N 1 ATOM 6923 C CA . ASN C 1 102 ? 2.590 -184.601 15.742 1.00 14.87 ? 160 ASN E CA 1 ATOM 6924 C C . ASN C 1 102 ? 3.315 -183.868 14.614 1.00 19.42 ? 160 ASN E C 1 ATOM 6925 O O . ASN C 1 102 ? 3.588 -182.672 14.703 1.00 14.35 ? 160 ASN E O 1 ATOM 6926 C CB . ASN C 1 102 ? 1.097 -184.282 15.682 1.00 16.92 ? 160 ASN E CB 1 ATOM 6927 C CG . ASN C 1 102 ? 0.469 -184.681 14.358 1.00 31.80 ? 160 ASN E CG 1 ATOM 6928 O OD1 . ASN C 1 102 ? 0.235 -185.861 14.104 1.00 22.41 ? 160 ASN E OD1 1 ATOM 6929 N ND2 . ASN C 1 102 ? 0.190 -183.696 13.508 1.00 22.75 ? 160 ASN E ND2 1 ATOM 6930 N N . LEU C 1 103 ? 3.624 -184.609 13.553 1.00 15.80 ? 161 LEU E N 1 ATOM 6931 C CA . LEU C 1 103 ? 4.264 -184.052 12.367 1.00 21.34 ? 161 LEU E CA 1 ATOM 6932 C C . LEU C 1 103 ? 3.326 -183.069 11.667 1.00 20.27 ? 161 LEU E C 1 ATOM 6933 O O . LEU C 1 103 ? 2.195 -183.420 11.327 1.00 18.29 ? 161 LEU E O 1 ATOM 6934 C CB . LEU C 1 103 ? 4.668 -185.178 11.413 1.00 18.71 ? 161 LEU E CB 1 ATOM 6935 C CG . LEU C 1 103 ? 5.280 -184.804 10.062 1.00 20.45 ? 161 LEU E CG 1 ATOM 6936 C CD1 . LEU C 1 103 ? 6.613 -184.100 10.241 1.00 21.25 ? 161 LEU E CD1 1 ATOM 6937 C CD2 . LEU C 1 103 ? 5.437 -186.052 9.206 1.00 28.34 ? 161 LEU E CD2 1 ATOM 6938 N N . ASN C 1 104 ? 3.801 -181.845 11.452 1.00 21.91 ? 162 ASN E N 1 ATOM 6939 C CA . ASN C 1 104 ? 2.965 -180.783 10.895 1.00 22.47 ? 162 ASN E CA 1 ATOM 6940 C C . ASN C 1 104 ? 3.364 -180.370 9.476 1.00 21.10 ? 162 ASN E C 1 ATOM 6941 O O . ASN C 1 104 ? 2.913 -179.339 8.977 1.00 24.70 ? 162 ASN E O 1 ATOM 6942 C CB . ASN C 1 104 ? 3.006 -179.560 11.813 1.00 18.24 ? 162 ASN E CB 1 ATOM 6943 C CG . ASN C 1 104 ? 4.362 -178.883 11.821 1.00 28.40 ? 162 ASN E CG 1 ATOM 6944 O OD1 . ASN C 1 104 ? 5.382 -179.500 11.514 1.00 25.21 ? 162 ASN E OD1 1 ATOM 6945 N ND2 . ASN C 1 104 ? 4.379 -177.604 12.172 1.00 34.88 ? 162 ASN E ND2 1 ATOM 6946 N N . PHE C 1 105 ? 4.201 -181.172 8.823 1.00 18.96 ? 163 PHE E N 1 ATOM 6947 C CA . PHE C 1 105 ? 4.650 -180.854 7.467 1.00 19.72 ? 163 PHE E CA 1 ATOM 6948 C C . PHE C 1 105 ? 3.492 -180.977 6.481 1.00 21.48 ? 163 PHE E C 1 ATOM 6949 O O . PHE C 1 105 ? 2.527 -181.700 6.733 1.00 22.32 ? 163 PHE E O 1 ATOM 6950 C CB . PHE C 1 105 ? 5.799 -181.769 7.029 1.00 20.85 ? 163 PHE E CB 1 ATOM 6951 C CG . PHE C 1 105 ? 7.091 -181.548 7.780 1.00 22.64 ? 163 PHE E CG 1 ATOM 6952 C CD1 . PHE C 1 105 ? 7.136 -180.768 8.925 1.00 25.79 ? 163 PHE E CD1 1 ATOM 6953 C CD2 . PHE C 1 105 ? 8.267 -182.124 7.325 1.00 25.03 ? 163 PHE E CD2 1 ATOM 6954 C CE1 . PHE C 1 105 ? 8.326 -180.576 9.604 1.00 27.62 ? 163 PHE E CE1 1 ATOM 6955 C CE2 . PHE C 1 105 ? 9.459 -181.932 8.000 1.00 25.86 ? 163 PHE E CE2 1 ATOM 6956 C CZ . PHE C 1 105 ? 9.487 -181.157 9.140 1.00 25.05 ? 163 PHE E CZ 1 ATOM 6957 N N . VAL C 1 106 ? 3.596 -180.272 5.359 1.00 20.75 ? 164 VAL E N 1 ATOM 6958 C CA . VAL C 1 106 ? 2.537 -180.265 4.356 1.00 20.11 ? 164 VAL E CA 1 ATOM 6959 C C . VAL C 1 106 ? 3.090 -180.381 2.945 1.00 15.38 ? 164 VAL E C 1 ATOM 6960 O O . VAL C 1 106 ? 4.257 -180.082 2.694 1.00 21.67 ? 164 VAL E O 1 ATOM 6961 C CB . VAL C 1 106 ? 1.689 -178.978 4.430 1.00 24.17 ? 164 VAL E CB 1 ATOM 6962 C CG1 . VAL C 1 106 ? 0.978 -178.876 5.771 1.00 23.30 ? 164 VAL E CG1 1 ATOM 6963 C CG2 . VAL C 1 106 ? 2.559 -177.750 4.184 1.00 20.93 ? 164 VAL E CG2 1 ATOM 6964 N N . THR C 1 107 ? 2.231 -180.804 2.024 1.00 18.63 ? 165 THR E N 1 ATOM 6965 C CA . THR C 1 107 ? 2.564 -180.794 0.606 1.00 23.94 ? 165 THR E CA 1 ATOM 6966 C C . THR C 1 107 ? 2.648 -179.346 0.124 1.00 27.55 ? 165 THR E C 1 ATOM 6967 O O . THR C 1 107 ? 2.228 -178.433 0.836 1.00 22.13 ? 165 THR E O 1 ATOM 6968 C CB . THR C 1 107 ? 1.518 -181.553 -0.228 1.00 19.42 ? 165 THR E CB 1 ATOM 6969 O OG1 . THR C 1 107 ? 0.257 -180.877 -0.151 1.00 21.94 ? 165 THR E OG1 1 ATOM 6970 C CG2 . THR C 1 107 ? 1.358 -182.975 0.277 1.00 18.84 ? 165 THR E CG2 1 ATOM 6971 N N . PRO C 1 108 ? 3.192 -179.127 -1.085 1.00 28.76 ? 166 PRO E N 1 ATOM 6972 C CA . PRO C 1 108 ? 3.243 -177.765 -1.630 1.00 27.16 ? 166 PRO E CA 1 ATOM 6973 C C . PRO C 1 108 ? 1.871 -177.091 -1.694 1.00 27.99 ? 166 PRO E C 1 ATOM 6974 O O . PRO C 1 108 ? 1.787 -175.869 -1.580 1.00 30.44 ? 166 PRO E O 1 ATOM 6975 C CB . PRO C 1 108 ? 3.812 -177.975 -3.035 1.00 32.69 ? 166 PRO E CB 1 ATOM 6976 C CG . PRO C 1 108 ? 4.632 -179.208 -2.922 1.00 27.87 ? 166 PRO E CG 1 ATOM 6977 C CD . PRO C 1 108 ? 3.900 -180.090 -1.949 1.00 25.88 ? 166 PRO E CD 1 ATOM 6978 N N . SER C 1 109 ? 0.815 -177.882 -1.860 1.00 23.48 ? 167 SER E N 1 ATOM 6979 C CA . SER C 1 109 ? -0.538 -177.343 -1.940 1.00 19.47 ? 167 SER E CA 1 ATOM 6980 C C . SER C 1 109 ? -1.162 -177.122 -0.560 1.00 28.32 ? 167 SER E C 1 ATOM 6981 O O . SER C 1 109 ? -2.270 -176.596 -0.457 1.00 24.03 ? 167 SER E O 1 ATOM 6982 C CB . SER C 1 109 ? -1.428 -178.276 -2.758 1.00 24.59 ? 167 SER E CB 1 ATOM 6983 O OG . SER C 1 109 ? -1.669 -179.486 -2.058 1.00 31.54 ? 167 SER E OG 1 ATOM 6984 N N . GLY C 1 110 ? -0.459 -177.536 0.492 1.00 25.50 ? 168 GLY E N 1 ATOM 6985 C CA . GLY C 1 110 ? -0.901 -177.295 1.855 1.00 25.41 ? 168 GLY E CA 1 ATOM 6986 C C . GLY C 1 110 ? -1.621 -178.458 2.514 1.00 28.26 ? 168 GLY E C 1 ATOM 6987 O O . GLY C 1 110 ? -2.240 -178.289 3.564 1.00 25.12 ? 168 GLY E O 1 ATOM 6988 N N . GLN C 1 111 ? -1.542 -179.640 1.912 1.00 19.49 ? 169 GLN E N 1 ATOM 6989 C CA . GLN C 1 111 ? -2.185 -180.823 2.477 1.00 25.71 ? 169 GLN E CA 1 ATOM 6990 C C . GLN C 1 111 ? -1.331 -181.427 3.587 1.00 20.56 ? 169 GLN E C 1 ATOM 6991 O O . GLN C 1 111 ? -0.145 -181.692 3.393 1.00 20.12 ? 169 GLN E O 1 ATOM 6992 C CB . GLN C 1 111 ? -2.445 -181.869 1.388 1.00 26.34 ? 169 GLN E CB 1 ATOM 6993 C CG . GLN C 1 111 ? -2.980 -183.193 1.910 1.00 20.43 ? 169 GLN E CG 1 ATOM 6994 C CD . GLN C 1 111 ? -4.246 -183.027 2.718 1.00 30.83 ? 169 GLN E CD 1 ATOM 6995 O OE1 . GLN C 1 111 ? -5.176 -182.337 2.301 0.93 26.98 ? 169 GLN E OE1 1 ATOM 6996 N NE2 . GLN C 1 111 ? -4.285 -183.652 3.889 0.88 31.38 ? 169 GLN E NE2 1 ATOM 6997 N N . ARG C 1 112 ? -1.945 -181.641 4.746 1.00 21.66 ? 170 ARG E N 1 ATOM 6998 C CA . ARG C 1 112 ? -1.284 -182.304 5.867 1.00 22.51 ? 170 ARG E CA 1 ATOM 6999 C C . ARG C 1 112 ? -0.945 -183.753 5.552 1.00 17.14 ? 170 ARG E C 1 ATOM 7000 O O . ARG C 1 112 ? -1.738 -184.464 4.935 1.00 27.40 ? 170 ARG E O 1 ATOM 7001 C CB . ARG C 1 112 ? -2.172 -182.284 7.109 1.00 19.74 ? 170 ARG E CB 1 ATOM 7002 C CG . ARG C 1 112 ? -2.311 -180.950 7.797 1.00 24.10 ? 170 ARG E CG 1 ATOM 7003 C CD . ARG C 1 112 ? -3.383 -181.055 8.874 1.00 33.34 ? 170 ARG E CD 1 ATOM 7004 N NE . ARG C 1 112 ? -3.333 -179.963 9.840 1.00 42.08 ? 170 ARG E NE 1 ATOM 7005 C CZ . ARG C 1 112 ? -2.462 -179.884 10.843 1.00 49.68 ? 170 ARG E CZ 1 ATOM 7006 N NH1 . ARG C 1 112 ? -1.540 -180.826 11.016 1.00 31.59 ? 170 ARG E NH1 1 ATOM 7007 N NH2 . ARG C 1 112 ? -2.506 -178.851 11.671 1.00 39.86 ? 170 ARG E NH2 1 ATOM 7008 N N . ILE C 1 113 ? 0.227 -184.192 5.995 1.00 18.73 ? 171 ILE E N 1 ATOM 7009 C CA . ILE C 1 113 ? 0.553 -185.612 5.992 1.00 20.76 ? 171 ILE E CA 1 ATOM 7010 C C . ILE C 1 113 ? 0.029 -186.260 7.273 1.00 23.60 ? 171 ILE E C 1 ATOM 7011 O O . ILE C 1 113 ? -0.227 -187.463 7.308 1.00 22.56 ? 171 ILE E O 1 ATOM 7012 C CB . ILE C 1 113 ? 2.069 -185.855 5.871 1.00 22.66 ? 171 ILE E CB 1 ATOM 7013 C CG1 . ILE C 1 113 ? 2.354 -187.353 5.722 1.00 29.43 ? 171 ILE E CG1 1 ATOM 7014 C CG2 . ILE C 1 113 ? 2.802 -185.274 7.075 1.00 26.32 ? 171 ILE E CG2 1 ATOM 7015 C CD1 . ILE C 1 113 ? 3.794 -187.678 5.385 1.00 35.37 ? 171 ILE E CD1 1 ATOM 7016 N N . SER C 1 114 ? -0.133 -185.456 8.322 1.00 19.67 ? 172 SER E N 1 ATOM 7017 C CA . SER C 1 114 ? -0.565 -185.968 9.618 1.00 17.62 ? 172 SER E CA 1 ATOM 7018 C C . SER C 1 114 ? -1.364 -184.924 10.401 1.00 17.57 ? 172 SER E C 1 ATOM 7019 O O . SER C 1 114 ? -0.941 -183.772 10.496 1.00 21.69 ? 172 SER E O 1 ATOM 7020 C CB . SER C 1 114 ? 0.647 -186.413 10.440 1.00 19.83 ? 172 SER E CB 1 ATOM 7021 O OG . SER C 1 114 ? 0.242 -186.972 11.676 1.00 16.75 ? 172 SER E OG 1 ATOM 7022 N N . PRO C 1 115 ? -2.519 -185.314 10.970 1.00 20.17 ? 173 PRO E N 1 ATOM 7023 C CA . PRO C 1 115 ? -3.186 -186.621 10.885 1.00 18.59 ? 173 PRO E CA 1 ATOM 7024 C C . PRO C 1 115 ? -3.710 -186.934 9.488 1.00 25.90 ? 173 PRO E C 1 ATOM 7025 O O . PRO C 1 115 ? -4.069 -186.015 8.751 1.00 23.60 ? 173 PRO E O 1 ATOM 7026 C CB . PRO C 1 115 ? -4.349 -186.490 11.873 1.00 21.38 ? 173 PRO E CB 1 ATOM 7027 C CG . PRO C 1 115 ? -4.565 -185.033 12.028 1.00 23.40 ? 173 PRO E CG 1 ATOM 7028 C CD . PRO C 1 115 ? -3.221 -184.410 11.896 1.00 23.00 ? 173 PRO E CD 1 ATOM 7029 N N . PHE C 1 116 ? -3.752 -188.217 9.142 1.00 19.48 ? 174 PHE E N 1 ATOM 7030 C CA . PHE C 1 116 ? -4.205 -188.654 7.826 1.00 20.48 ? 174 PHE E CA 1 ATOM 7031 C C . PHE C 1 116 ? -5.441 -189.544 7.952 1.00 22.60 ? 174 PHE E C 1 ATOM 7032 O O . PHE C 1 116 ? -5.438 -190.501 8.725 1.00 23.51 ? 174 PHE E O 1 ATOM 7033 C CB . PHE C 1 116 ? -3.088 -189.405 7.102 1.00 21.62 ? 174 PHE E CB 1 ATOM 7034 C CG . PHE C 1 116 ? -3.206 -189.369 5.608 1.00 22.37 ? 174 PHE E CG 1 ATOM 7035 C CD1 . PHE C 1 116 ? -2.813 -188.246 4.898 1.00 19.85 ? 174 PHE E CD1 1 ATOM 7036 C CD2 . PHE C 1 116 ? -3.707 -190.455 4.912 1.00 21.95 ? 174 PHE E CD2 1 ATOM 7037 C CE1 . PHE C 1 116 ? -2.919 -188.206 3.521 1.00 26.33 ? 174 PHE E CE1 1 ATOM 7038 C CE2 . PHE C 1 116 ? -3.815 -190.420 3.532 1.00 29.50 ? 174 PHE E CE2 1 ATOM 7039 C CZ . PHE C 1 116 ? -3.420 -189.294 2.837 1.00 24.15 ? 174 PHE E CZ 1 ATOM 7040 N N . PRO C 1 117 ? -6.501 -189.240 7.186 1.00 23.65 ? 175 PRO E N 1 ATOM 7041 C CA . PRO C 1 117 ? -7.754 -189.995 7.308 1.00 25.60 ? 175 PRO E CA 1 ATOM 7042 C C . PRO C 1 117 ? -7.663 -191.403 6.727 1.00 22.47 ? 175 PRO E C 1 ATOM 7043 O O . PRO C 1 117 ? -7.083 -191.599 5.659 1.00 20.86 ? 175 PRO E O 1 ATOM 7044 C CB . PRO C 1 117 ? -8.745 -189.144 6.515 1.00 29.75 ? 175 PRO E CB 1 ATOM 7045 C CG . PRO C 1 117 ? -7.908 -188.505 5.467 1.00 31.32 ? 175 PRO E CG 1 ATOM 7046 C CD . PRO C 1 117 ? -6.574 -188.235 6.110 1.00 26.68 ? 175 PRO E CD 1 ATOM 7047 N N . MET C 1 118 ? -8.252 -192.368 7.423 1.00 20.41 ? 176 MET E N 1 ATOM 7048 C CA . MET C 1 118 ? -8.173 -193.762 7.011 1.00 20.91 ? 176 MET E CA 1 ATOM 7049 C C . MET C 1 118 ? -8.927 -193.999 5.706 1.00 15.01 ? 176 MET E C 1 ATOM 7050 O O . MET C 1 118 ? -8.566 -194.884 4.932 1.00 22.15 ? 176 MET E O 1 ATOM 7051 C CB . MET C 1 118 ? -8.724 -194.674 8.113 1.00 26.76 ? 176 MET E CB 1 ATOM 7052 C CG . MET C 1 118 ? -8.641 -196.167 7.805 1.00 28.24 ? 176 MET E CG 1 ATOM 7053 S SD . MET C 1 118 ? -7.005 -196.713 7.270 1.00 29.66 ? 176 MET E SD 1 ATOM 7054 C CE . MET C 1 118 ? -5.968 -196.069 8.580 1.00 26.78 ? 176 MET E CE 1 ATOM 7055 N N . GLU C 1 119 ? -9.966 -193.204 5.460 1.00 22.02 ? 177 GLU E N 1 ATOM 7056 C CA . GLU C 1 119 ? -10.775 -193.358 4.251 1.00 29.43 ? 177 GLU E CA 1 ATOM 7057 C C . GLU C 1 119 ? -9.938 -193.197 2.985 1.00 26.72 ? 177 GLU E C 1 ATOM 7058 O O . GLU C 1 119 ? -10.209 -193.838 1.969 1.00 36.23 ? 177 GLU E O 1 ATOM 7059 C CB . GLU C 1 119 ? -11.926 -192.349 4.231 1.00 29.99 ? 177 GLU E CB 1 ATOM 7060 C CG . GLU C 1 119 ? -12.956 -192.549 5.338 1.00 34.99 ? 177 GLU E CG 1 ATOM 7061 C CD . GLU C 1 119 ? -12.715 -191.674 6.557 1.00 33.79 ? 177 GLU E CD 1 ATOM 7062 O OE1 . GLU C 1 119 ? -13.646 -191.542 7.379 1.00 32.48 ? 177 GLU E OE1 1 ATOM 7063 O OE2 . GLU C 1 119 ? -11.603 -191.122 6.699 1.00 37.56 ? 177 GLU E OE2 1 ATOM 7064 N N . LEU C 1 120 ? -8.921 -192.345 3.052 1.00 22.55 ? 178 LEU E N 1 ATOM 7065 C CA . LEU C 1 120 ? -8.074 -192.075 1.895 1.00 26.81 ? 178 LEU E CA 1 ATOM 7066 C C . LEU C 1 120 ? -7.023 -193.162 1.671 1.00 31.96 ? 178 LEU E C 1 ATOM 7067 O O . LEU C 1 120 ? -6.455 -193.263 0.584 1.00 39.14 ? 178 LEU E O 1 ATOM 7068 C CB . LEU C 1 120 ? -7.386 -190.719 2.050 1.00 30.27 ? 178 LEU E CB 1 ATOM 7069 C CG . LEU C 1 120 ? -8.163 -189.516 1.509 1.00 38.87 ? 178 LEU E CG 1 ATOM 7070 C CD1 . LEU C 1 120 ? -9.497 -189.342 2.217 1.00 43.77 ? 178 LEU E CD1 1 ATOM 7071 C CD2 . LEU C 1 120 ? -7.317 -188.264 1.631 1.00 44.85 ? 178 LEU E CD2 1 ATOM 7072 N N . LEU C 1 121 ? -6.769 -193.970 2.696 1.00 26.87 ? 179 LEU E N 1 ATOM 7073 C CA . LEU C 1 121 ? -5.789 -195.048 2.598 1.00 24.06 ? 179 LEU E CA 1 ATOM 7074 C C . LEU C 1 121 ? -6.430 -196.363 2.160 1.00 18.14 ? 179 LEU E C 1 ATOM 7075 O O . LEU C 1 121 ? -5.799 -197.167 1.477 1.00 26.63 ? 179 LEU E O 1 ATOM 7076 C CB . LEU C 1 121 ? -5.081 -195.255 3.940 1.00 24.44 ? 179 LEU E CB 1 ATOM 7077 C CG . LEU C 1 121 ? -4.176 -194.131 4.443 1.00 20.02 ? 179 LEU E CG 1 ATOM 7078 C CD1 . LEU C 1 121 ? -3.718 -194.441 5.859 1.00 25.33 ? 179 LEU E CD1 1 ATOM 7079 C CD2 . LEU C 1 121 ? -2.979 -193.935 3.534 1.00 26.31 ? 179 LEU E CD2 1 ATOM 7080 N N . GLU C 1 122 ? -7.683 -196.576 2.550 1.00 20.69 ? 180 GLU E N 1 ATOM 7081 C CA . GLU C 1 122 ? -8.317 -197.883 2.396 1.00 41.34 ? 180 GLU E CA 1 ATOM 7082 C C . GLU C 1 122 ? -8.829 -198.150 0.977 1.00 40.30 ? 180 GLU E C 1 ATOM 7083 O O . GLU C 1 122 ? -9.394 -199.210 0.708 1.00 39.36 ? 180 GLU E O 1 ATOM 7084 C CB . GLU C 1 122 ? -9.464 -198.025 3.402 1.00 31.16 ? 180 GLU E CB 1 ATOM 7085 C CG . GLU C 1 122 ? -10.688 -197.175 3.103 1.00 42.16 ? 180 GLU E CG 1 ATOM 7086 C CD . GLU C 1 122 ? -11.662 -197.138 4.267 1.00 52.56 ? 180 GLU E CD 1 ATOM 7087 O OE1 . GLU C 1 122 ? -11.423 -197.848 5.268 1.00 54.68 ? 180 GLU E OE1 1 ATOM 7088 O OE2 . GLU C 1 122 ? -12.665 -196.398 4.185 1.00 51.70 ? 180 GLU E OE2 1 ATOM 7089 N N . LYS C 1 123 ? -8.623 -197.190 0.078 1.00 40.79 ? 181 LYS E N 1 ATOM 7090 C CA . LYS C 1 123 ? -8.972 -197.348 -1.332 1.00 43.08 ? 181 LYS E CA 1 ATOM 7091 C C . LYS C 1 123 ? -7.822 -196.886 -2.233 1.00 29.98 ? 181 LYS E C 1 ATOM 7092 O O . LYS C 1 123 ? -8.014 -196.642 -3.424 1.00 56.26 ? 181 LYS E O 1 ATOM 7093 C CB . LYS C 1 123 ? -10.249 -196.566 -1.654 1.00 49.18 ? 181 LYS E CB 1 ATOM 7094 C CG . LYS C 1 123 ? -11.534 -197.267 -1.225 1.00 60.45 ? 181 LYS E CG 1 ATOM 7095 C CD . LYS C 1 123 ? -12.733 -196.327 -1.252 1.00 57.63 ? 181 LYS E CD 1 ATOM 7096 C CE . LYS C 1 123 ? -12.728 -195.365 -0.072 1.00 61.96 ? 181 LYS E CE 1 ATOM 7097 N NZ . LYS C 1 123 ? -13.507 -195.883 1.089 1.00 74.09 ? 181 LYS E NZ 1 ATOM 7098 N N . ASN C 1 124 ? -6.640 -196.745 -1.660 1.00 39.05 ? 182 ASN E N 1 ATOM 7099 C CA . ASN C 1 124 ? -5.452 -196.256 -2.358 1.00 33.73 ? 182 ASN E CA 1 ATOM 7100 C C . ASN C 1 124 ? -4.539 -197.306 -2.972 1.00 52.42 ? 182 ASN E C 1 ATOM 7101 O O . ASN C 1 124 ? -4.482 -198.427 -2.491 1.00 47.45 ? 182 ASN E O 1 ATOM 7102 C CB . ASN C 1 124 ? -4.635 -195.401 -1.408 1.00 33.70 ? 182 ASN E CB 1 ATOM 7103 C CG . ASN C 1 124 ? -3.620 -194.541 -2.119 1.00 36.11 ? 182 ASN E CG 1 ATOM 7104 O OD1 . ASN C 1 124 ? -2.537 -194.966 -2.434 1.00 34.40 ? 182 ASN E OD1 1 ATOM 7105 N ND2 . ASN C 1 124 ? -3.979 -193.310 -2.347 1.00 58.04 ? 182 ASN E ND2 1 ATOM 7106 N N . SER C 1 125 ? -3.846 -196.927 -4.046 1.00 35.39 ? 183 SER E N 1 ATOM 7107 C CA . SER C 1 125 ? -2.915 -197.812 -4.758 1.00 54.55 ? 183 SER E CA 1 ATOM 7108 C C . SER C 1 125 ? -1.633 -198.245 -4.053 1.00 45.14 ? 183 SER E C 1 ATOM 7109 O O . SER C 1 125 ? -1.223 -199.371 -4.153 1.00 53.80 ? 183 SER E O 1 ATOM 7110 C CB . SER C 1 125 ? -2.546 -197.238 -6.138 1.00 50.94 ? 183 SER E CB 1 ATOM 7111 O OG . SER C 1 125 ? -1.294 -196.582 -6.142 1.00 42.55 ? 183 SER E OG 1 ATOM 7112 N N . ASN C 1 126 ? -1.011 -197.314 -3.360 1.00 36.51 ? 184 ASN E N 1 ATOM 7113 C CA . ASN C 1 126 ? 0.247 -197.535 -2.677 1.00 58.25 ? 184 ASN E CA 1 ATOM 7114 C C . ASN C 1 126 ? 0.124 -198.265 -1.346 1.00 46.81 ? 184 ASN E C 1 ATOM 7115 O O . ASN C 1 126 ? 1.104 -198.506 -0.674 1.00 59.33 ? 184 ASN E O 1 ATOM 7116 C CB . ASN C 1 126 ? 0.903 -196.183 -2.377 1.00 54.67 ? 184 ASN E CB 1 ATOM 7117 C CG . ASN C 1 126 ? 0.927 -195.245 -3.566 1.00 53.34 ? 184 ASN E CG 1 ATOM 7118 O OD1 . ASN C 1 126 ? 1.868 -195.248 -4.337 1.00 49.89 ? 184 ASN E OD1 1 ATOM 7119 N ND2 . ASN C 1 126 ? -0.091 -194.410 -3.688 1.00 35.93 ? 184 ASN E ND2 1 ATOM 7120 N N . ILE C 1 127 ? -1.092 -198.564 -0.957 1.00 32.50 ? 185 ILE E N 1 ATOM 7121 C CA . ILE C 1 127 ? -1.409 -199.124 0.354 1.00 33.67 ? 185 ILE E CA 1 ATOM 7122 C C . ILE C 1 127 ? -2.039 -200.509 0.209 1.00 32.11 ? 185 ILE E C 1 ATOM 7123 O O . ILE C 1 127 ? -3.191 -200.631 -0.204 1.00 35.99 ? 185 ILE E O 1 ATOM 7124 C CB . ILE C 1 127 ? -2.365 -198.192 1.132 1.00 30.84 ? 185 ILE E CB 1 ATOM 7125 C CG1 . ILE C 1 127 ? -1.783 -196.772 1.226 1.00 28.13 ? 185 ILE E CG1 1 ATOM 7126 C CG2 . ILE C 1 127 ? -2.654 -198.752 2.515 1.00 27.86 ? 185 ILE E CG2 1 ATOM 7127 C CD1 . ILE C 1 127 ? -0.562 -196.643 2.121 1.00 29.55 ? 185 ILE E CD1 1 ATOM 7128 N N . LYS C 1 128 ? -1.280 -201.543 0.566 1.00 26.02 ? 186 LYS E N 1 ATOM 7129 C CA . LYS C 1 128 ? -1.693 -202.928 0.344 1.00 38.86 ? 186 LYS E CA 1 ATOM 7130 C C . LYS C 1 128 ? -2.112 -203.666 1.617 1.00 43.53 ? 186 LYS E C 1 ATOM 7131 O O . LYS C 1 128 ? -2.553 -204.814 1.549 1.00 33.15 ? 186 LYS E O 1 ATOM 7132 C CB . LYS C 1 128 ? -0.558 -203.698 -0.333 1.00 38.93 ? 186 LYS E CB 1 ATOM 7133 C CG . LYS C 1 128 ? -0.281 -203.253 -1.758 1.00 51.40 ? 186 LYS E CG 1 ATOM 7134 C CD . LYS C 1 128 ? 0.975 -203.914 -2.301 1.00 76.40 ? 186 LYS E CD 1 ATOM 7135 C CE . LYS C 1 128 ? 1.499 -203.205 -3.538 1.00 65.71 ? 186 LYS E CE 1 ATOM 7136 N NZ . LYS C 1 128 ? 2.978 -203.340 -3.654 1.00 81.08 ? 186 LYS E NZ 1 ATOM 7137 N N . ALA C 1 129 ? -1.972 -203.020 2.770 1.00 33.99 ? 187 ALA E N 1 ATOM 7138 C CA . ALA C 1 129 ? -2.347 -203.642 4.038 1.00 31.27 ? 187 ALA E CA 1 ATOM 7139 C C . ALA C 1 129 ? -3.828 -204.011 4.035 1.00 28.14 ? 187 ALA E C 1 ATOM 7140 O O . ALA C 1 129 ? -4.635 -203.366 3.366 1.00 30.72 ? 187 ALA E O 1 ATOM 7141 C CB . ALA C 1 129 ? -2.027 -202.713 5.209 1.00 24.44 ? 187 ALA E CB 1 ATOM 7142 N N . SER C 1 130 ? -4.174 -205.051 4.790 1.00 30.15 ? 188 SER E N 1 ATOM 7143 C CA . SER C 1 130 ? -5.530 -205.596 4.785 1.00 32.67 ? 188 SER E CA 1 ATOM 7144 C C . SER C 1 130 ? -6.411 -205.036 5.902 1.00 26.24 ? 188 SER E C 1 ATOM 7145 O O . SER C 1 130 ? -7.627 -205.237 5.891 1.00 28.45 ? 188 SER E O 1 ATOM 7146 C CB . SER C 1 130 ? -5.477 -207.123 4.893 1.00 37.12 ? 188 SER E CB 1 ATOM 7147 O OG . SER C 1 130 ? -4.836 -207.532 6.090 1.00 46.23 ? 188 SER E OG 1 ATOM 7148 N N . THR C 1 131 ? -5.802 -204.340 6.860 1.00 22.99 ? 189 THR E N 1 ATOM 7149 C CA . THR C 1 131 ? -6.547 -203.741 7.967 1.00 28.89 ? 189 THR E CA 1 ATOM 7150 C C . THR C 1 131 ? -6.179 -202.267 8.134 1.00 14.12 ? 189 THR E C 1 ATOM 7151 O O . THR C 1 131 ? -5.121 -201.830 7.685 1.00 21.53 ? 189 THR E O 1 ATOM 7152 C CB . THR C 1 131 ? -6.282 -204.479 9.294 1.00 26.88 ? 189 THR E CB 1 ATOM 7153 O OG1 . THR C 1 131 ? -4.941 -204.227 9.726 1.00 23.97 ? 189 THR E OG1 1 ATOM 7154 C CG2 . THR C 1 131 ? -6.488 -205.983 9.133 1.00 35.25 ? 189 THR E CG2 1 ATOM 7155 N N . ASP C 1 132 ? -7.054 -201.510 8.790 1.00 22.69 ? 190 ASP E N 1 ATOM 7156 C CA . ASP C 1 132 ? -6.834 -200.083 9.012 1.00 30.09 ? 190 ASP E CA 1 ATOM 7157 C C . ASP C 1 132 ? -5.524 -199.821 9.757 1.00 24.12 ? 190 ASP E C 1 ATOM 7158 O O . ASP C 1 132 ? -4.727 -198.965 9.354 1.00 24.42 ? 190 ASP E O 1 ATOM 7159 C CB . ASP C 1 132 ? -8.007 -199.481 9.790 1.00 28.67 ? 190 ASP E CB 1 ATOM 7160 C CG . ASP C 1 132 ? -9.316 -199.533 9.016 1.00 32.09 ? 190 ASP E CG 1 ATOM 7161 O OD1 . ASP C 1 132 ? -9.278 -199.700 7.779 1.00 32.92 ? 190 ASP E OD1 1 ATOM 7162 O OD2 . ASP C 1 132 ? -10.385 -199.399 9.648 1.00 41.09 ? 190 ASP E OD2 1 ATOM 7163 N N . LEU C 1 133 ? -5.303 -200.560 10.842 1.00 24.11 ? 191 LEU E N 1 ATOM 7164 C CA . LEU C 1 133 ? -4.079 -200.426 11.628 1.00 21.25 ? 191 LEU E CA 1 ATOM 7165 C C . LEU C 1 133 ? -2.859 -200.703 10.760 1.00 16.69 ? 191 LEU E C 1 ATOM 7166 O O . LEU C 1 133 ? -1.865 -199.965 10.793 1.00 26.15 ? 191 LEU E O 1 ATOM 7167 C CB . LEU C 1 133 ? -4.102 -201.377 12.829 1.00 23.13 ? 191 LEU E CB 1 ATOM 7168 C CG . LEU C 1 133 ? -2.886 -201.339 13.758 1.00 25.80 ? 191 LEU E CG 1 ATOM 7169 C CD1 . LEU C 1 133 ? -2.618 -199.924 14.259 1.00 23.09 ? 191 LEU E CD1 1 ATOM 7170 C CD2 . LEU C 1 133 ? -3.095 -202.283 14.929 1.00 25.55 ? 191 LEU E CD2 1 ATOM 7171 N N . GLY C 1 134 ? -2.946 -201.771 9.975 1.00 25.88 ? 192 GLY E N 1 ATOM 7172 C CA . GLY C 1 134 ? -1.898 -202.116 9.035 1.00 18.45 ? 192 GLY E CA 1 ATOM 7173 C C . GLY C 1 134 ? -1.690 -201.021 8.004 1.00 14.23 ? 192 GLY E C 1 ATOM 7174 O O . GLY C 1 134 ? -0.563 -200.760 7.583 1.00 17.88 ? 192 GLY E O 1 ATOM 7175 N N . ARG C 1 135 ? -2.782 -200.378 7.596 1.00 16.63 ? 193 ARG E N 1 ATOM 7176 C CA . ARG C 1 135 ? -2.708 -199.298 6.618 1.00 23.05 ? 193 ARG E CA 1 ATOM 7177 C C . ARG C 1 135 ? -1.993 -198.088 7.209 1.00 20.05 ? 193 ARG E C 1 ATOM 7178 O O . ARG C 1 135 ? -1.140 -197.485 6.554 1.00 21.87 ? 193 ARG E O 1 ATOM 7179 C CB . ARG C 1 135 ? -4.106 -198.908 6.133 1.00 22.93 ? 193 ARG E CB 1 ATOM 7180 C CG . ARG C 1 135 ? -4.720 -199.917 5.182 1.00 24.66 ? 193 ARG E CG 1 ATOM 7181 C CD . ARG C 1 135 ? -6.160 -199.582 4.844 1.00 25.35 ? 193 ARG E CD 1 ATOM 7182 N NE . ARG C 1 135 ? -6.742 -200.594 3.963 1.00 27.65 ? 193 ARG E NE 1 ATOM 7183 C CZ . ARG C 1 135 ? -7.690 -201.466 4.305 1.00 32.09 ? 193 ARG E CZ 1 ATOM 7184 N NH1 . ARG C 1 135 ? -8.216 -201.473 5.525 1.00 37.54 ? 193 ARG E NH1 1 ATOM 7185 N NH2 . ARG C 1 135 ? -8.125 -202.339 3.408 1.00 41.72 ? 193 ARG E NH2 1 ATOM 7186 N N . CYS C 1 136 ? -2.339 -197.734 8.443 1.00 18.51 ? 194 CYS E N 1 ATOM 7187 C CA . CYS C 1 136 ? -1.639 -196.661 9.145 1.00 16.09 ? 194 CYS E CA 1 ATOM 7188 C C . CYS C 1 136 ? -0.148 -196.983 9.282 1.00 19.56 ? 194 CYS E C 1 ATOM 7189 O O . CYS C 1 136 ? 0.720 -196.163 8.941 1.00 22.24 ? 194 CYS E O 1 ATOM 7190 C CB . CYS C 1 136 ? -2.257 -196.429 10.528 1.00 21.10 ? 194 CYS E CB 1 ATOM 7191 S SG . CYS C 1 136 ? -1.564 -195.012 11.423 1.00 29.67 ? 194 CYS E SG 1 ATOM 7192 N N . ALA C 1 137 ? 0.146 -198.182 9.775 1.00 23.40 ? 195 ALA E N 1 ATOM 7193 C CA . ALA C 1 137 ? 1.530 -198.638 9.894 1.00 19.12 ? 195 ALA E CA 1 ATOM 7194 C C . ALA C 1 137 ? 2.270 -198.554 8.562 1.00 19.47 ? 195 ALA E C 1 ATOM 7195 O O . ALA C 1 137 ? 3.408 -198.083 8.495 1.00 20.71 ? 195 ALA E O 1 ATOM 7196 C CB . ALA C 1 137 ? 1.569 -200.061 10.418 1.00 26.48 ? 195 ALA E CB 1 ATOM 7197 N N . GLU C 1 138 ? 1.616 -199.019 7.503 1.00 19.58 ? 196 GLU E N 1 ATOM 7198 C CA . GLU C 1 138 ? 2.202 -199.004 6.168 1.00 26.21 ? 196 GLU E CA 1 ATOM 7199 C C . GLU C 1 138 ? 2.467 -197.574 5.711 1.00 20.12 ? 196 GLU E C 1 ATOM 7200 O O . GLU C 1 138 ? 3.523 -197.272 5.154 1.00 18.94 ? 196 GLU E O 1 ATOM 7201 C CB . GLU C 1 138 ? 1.279 -199.712 5.175 1.00 22.24 ? 196 GLU E CB 1 ATOM 7202 C CG . GLU C 1 138 ? 1.871 -199.876 3.782 1.00 22.44 ? 196 GLU E CG 1 ATOM 7203 C CD . GLU C 1 138 ? 0.948 -200.625 2.839 1.00 31.26 ? 196 GLU E CD 1 ATOM 7204 O OE1 . GLU C 1 138 ? 1.322 -200.812 1.659 1.00 35.51 ? 196 GLU E OE1 1 ATOM 7205 O OE2 . GLU C 1 138 ? -0.153 -201.026 3.274 1.00 34.78 ? 196 GLU E OE2 1 ATOM 7206 N N . PHE C 1 139 ? 1.494 -196.702 5.945 1.00 18.71 ? 197 PHE E N 1 ATOM 7207 C CA . PHE C 1 139 ? 1.640 -195.288 5.636 1.00 16.58 ? 197 PHE E CA 1 ATOM 7208 C C . PHE C 1 139 ? 2.853 -194.723 6.363 1.00 21.43 ? 197 PHE E C 1 ATOM 7209 O O . PHE C 1 139 ? 3.632 -193.960 5.789 1.00 15.95 ? 197 PHE E O 1 ATOM 7210 C CB . PHE C 1 139 ? 0.368 -194.527 6.020 1.00 25.88 ? 197 PHE E CB 1 ATOM 7211 C CG . PHE C 1 139 ? 0.392 -193.072 5.657 1.00 27.45 ? 197 PHE E CG 1 ATOM 7212 C CD1 . PHE C 1 139 ? 0.291 -192.672 4.335 1.00 25.46 ? 197 PHE E CD1 1 ATOM 7213 C CD2 . PHE C 1 139 ? 0.495 -192.101 6.640 1.00 31.09 ? 197 PHE E CD2 1 ATOM 7214 C CE1 . PHE C 1 139 ? 0.307 -191.333 3.999 1.00 28.43 ? 197 PHE E CE1 1 ATOM 7215 C CE2 . PHE C 1 139 ? 0.511 -190.760 6.311 1.00 30.42 ? 197 PHE E CE2 1 ATOM 7216 C CZ . PHE C 1 139 ? 0.417 -190.375 4.989 1.00 28.38 ? 197 PHE E CZ 1 ATOM 7217 N N . ALA C 1 140 ? 3.020 -195.106 7.625 1.00 15.48 ? 198 ALA E N 1 ATOM 7218 C CA . ALA C 1 140 ? 4.201 -194.689 8.378 1.00 17.98 ? 198 ALA E CA 1 ATOM 7219 C C . ALA C 1 140 ? 5.500 -195.271 7.818 1.00 22.97 ? 198 ALA E C 1 ATOM 7220 O O . ALA C 1 140 ? 6.507 -194.570 7.727 1.00 15.86 ? 198 ALA E O 1 ATOM 7221 C CB . ALA C 1 140 ? 4.053 -195.071 9.839 1.00 27.53 ? 198 ALA E CB 1 ATOM 7222 N N . PHE C 1 141 ? 5.492 -196.551 7.458 1.00 17.67 ? 199 PHE E N 1 ATOM 7223 C CA . PHE C 1 141 ? 6.700 -197.178 6.924 1.00 20.70 ? 199 PHE E CA 1 ATOM 7224 C C . PHE C 1 141 ? 7.126 -196.543 5.604 1.00 17.65 ? 199 PHE E C 1 ATOM 7225 O O . PHE C 1 141 ? 8.312 -196.497 5.281 1.00 18.85 ? 199 PHE E O 1 ATOM 7226 C CB . PHE C 1 141 ? 6.498 -198.682 6.726 1.00 23.59 ? 199 PHE E CB 1 ATOM 7227 C CG . PHE C 1 141 ? 7.719 -199.389 6.204 1.00 18.90 ? 199 PHE E CG 1 ATOM 7228 C CD1 . PHE C 1 141 ? 8.805 -199.623 7.030 1.00 17.49 ? 199 PHE E CD1 1 ATOM 7229 C CD2 . PHE C 1 141 ? 7.783 -199.810 4.886 1.00 23.63 ? 199 PHE E CD2 1 ATOM 7230 C CE1 . PHE C 1 141 ? 9.931 -200.267 6.554 1.00 23.29 ? 199 PHE E CE1 1 ATOM 7231 C CE2 . PHE C 1 141 ? 8.905 -200.455 4.405 1.00 25.03 ? 199 PHE E CE2 1 ATOM 7232 C CZ . PHE C 1 141 ? 9.982 -200.684 5.241 1.00 31.65 ? 199 PHE E CZ 1 ATOM 7233 N N . LYS C 1 142 ? 6.153 -196.045 4.849 1.00 20.02 ? 200 LYS E N 1 ATOM 7234 C CA . LYS C 1 142 ? 6.432 -195.446 3.551 1.00 24.99 ? 200 LYS E CA 1 ATOM 7235 C C . LYS C 1 142 ? 6.741 -193.954 3.665 1.00 28.42 ? 200 LYS E C 1 ATOM 7236 O O . LYS C 1 142 ? 6.650 -193.214 2.685 1.00 28.86 ? 200 LYS E O 1 ATOM 7237 C CB . LYS C 1 142 ? 5.253 -195.694 2.608 1.00 23.26 ? 200 LYS E CB 1 ATOM 7238 C CG . LYS C 1 142 ? 5.236 -197.118 2.086 1.00 23.63 ? 200 LYS E CG 1 ATOM 7239 C CD . LYS C 1 142 ? 3.998 -197.455 1.284 1.00 29.57 ? 200 LYS E CD 1 ATOM 7240 C CE . LYS C 1 142 ? 4.238 -198.726 0.479 1.00 35.29 ? 200 LYS E CE 1 ATOM 7241 N NZ . LYS C 1 142 ? 3.048 -199.608 0.411 1.00 39.00 ? 200 LYS E NZ 1 ATOM 7242 N N . THR C 1 143 ? 7.117 -193.528 4.870 1.00 25.37 ? 201 THR E N 1 ATOM 7243 C CA . THR C 1 143 ? 7.584 -192.168 5.119 1.00 18.63 ? 201 THR E CA 1 ATOM 7244 C C . THR C 1 143 ? 9.014 -192.202 5.656 1.00 20.90 ? 201 THR E C 1 ATOM 7245 O O . THR C 1 143 ? 9.294 -192.897 6.632 1.00 29.44 ? 201 THR E O 1 ATOM 7246 C CB . THR C 1 143 ? 6.682 -191.428 6.131 1.00 20.55 ? 201 THR E CB 1 ATOM 7247 O OG1 . THR C 1 143 ? 5.310 -191.537 5.733 1.00 24.46 ? 201 THR E OG1 1 ATOM 7248 C CG2 . THR C 1 143 ? 7.067 -189.959 6.220 1.00 31.13 ? 201 THR E CG2 1 ATOM 7249 N N . VAL C 1 144 ? 9.915 -191.457 5.019 1.00 19.10 ? 202 VAL E N 1 ATOM 7250 C CA . VAL C 1 144 ? 11.304 -191.380 5.466 1.00 20.73 ? 202 VAL E CA 1 ATOM 7251 C C . VAL C 1 144 ? 11.811 -189.943 5.477 1.00 25.37 ? 202 VAL E C 1 ATOM 7252 O O . VAL C 1 144 ? 11.316 -189.092 4.739 1.00 23.27 ? 202 VAL E O 1 ATOM 7253 C CB . VAL C 1 144 ? 12.240 -192.223 4.573 1.00 24.95 ? 202 VAL E CB 1 ATOM 7254 C CG1 . VAL C 1 144 ? 11.779 -193.675 4.537 1.00 27.26 ? 202 VAL E CG1 1 ATOM 7255 C CG2 . VAL C 1 144 ? 12.307 -191.650 3.164 1.00 30.78 ? 202 VAL E CG2 1 ATOM 7256 N N . ALA C 1 145 ? 12.811 -189.684 6.313 1.00 23.93 ? 203 ALA E N 1 ATOM 7257 C CA . ALA C 1 145 ? 13.433 -188.370 6.377 1.00 25.08 ? 203 ALA E CA 1 ATOM 7258 C C . ALA C 1 145 ? 14.350 -188.142 5.181 1.00 27.21 ? 203 ALA E C 1 ATOM 7259 O O . ALA C 1 145 ? 14.987 -189.075 4.688 1.00 25.86 ? 203 ALA E O 1 ATOM 7260 C CB . ALA C 1 145 ? 14.212 -188.219 7.666 1.00 23.40 ? 203 ALA E CB 1 ATOM 7261 N N . MET C 1 146 ? 14.405 -186.896 4.721 1.00 23.77 ? 204 MET E N 1 ATOM 7262 C CA . MET C 1 146 ? 15.352 -186.478 3.691 1.00 27.81 ? 204 MET E CA 1 ATOM 7263 C C . MET C 1 146 ? 16.550 -185.804 4.349 1.00 28.64 ? 204 MET E C 1 ATOM 7264 O O . MET C 1 146 ? 16.384 -185.019 5.283 1.00 30.46 ? 204 MET E O 1 ATOM 7265 C CB . MET C 1 146 ? 14.693 -185.514 2.701 1.00 28.47 ? 204 MET E CB 1 ATOM 7266 C CG . MET C 1 146 ? 13.419 -186.038 2.061 1.00 40.43 ? 204 MET E CG 1 ATOM 7267 S SD . MET C 1 146 ? 13.743 -187.152 0.687 1.00 62.60 ? 204 MET E SD 1 ATOM 7268 C CE . MET C 1 146 ? 13.227 -186.126 -0.690 1.00 62.62 ? 204 MET E CE 1 ATOM 7269 N N . ASP C 1 147 ? 17.752 -186.104 3.866 1.00 26.00 ? 205 ASP E N 1 ATOM 7270 C CA . ASP C 1 147 ? 18.957 -185.476 4.403 1.00 33.44 ? 205 ASP E CA 1 ATOM 7271 C C . ASP C 1 147 ? 19.148 -184.085 3.796 1.00 26.70 ? 205 ASP E C 1 ATOM 7272 O O . ASP C 1 147 ? 18.297 -183.610 3.045 1.00 27.28 ? 205 ASP E O 1 ATOM 7273 C CB . ASP C 1 147 ? 20.190 -186.357 4.156 1.00 40.10 ? 205 ASP E CB 1 ATOM 7274 C CG . ASP C 1 147 ? 20.408 -186.686 2.689 1.00 43.92 ? 205 ASP E CG 1 ATOM 7275 O OD1 . ASP C 1 147 ? 19.928 -185.937 1.812 1.00 38.35 ? 205 ASP E OD1 1 ATOM 7276 O OD2 . ASP C 1 147 ? 21.079 -187.704 2.414 1.00 47.78 ? 205 ASP E OD2 1 ATOM 7277 N N . LYS C 1 148 ? 20.261 -183.434 4.121 1.00 31.17 ? 206 LYS E N 1 ATOM 7278 C CA . LYS C 1 148 ? 20.501 -182.072 3.655 1.00 40.37 ? 206 LYS E CA 1 ATOM 7279 C C . LYS C 1 148 ? 20.718 -182.004 2.142 1.00 35.65 ? 206 LYS E C 1 ATOM 7280 O O . LYS C 1 148 ? 20.636 -180.928 1.550 1.00 32.87 ? 206 LYS E O 1 ATOM 7281 C CB . LYS C 1 148 ? 21.704 -181.465 4.380 1.00 35.49 ? 206 LYS E CB 1 ATOM 7282 C CG . LYS C 1 148 ? 21.468 -181.237 5.863 1.00 54.77 ? 206 LYS E CG 1 ATOM 7283 C CD . LYS C 1 148 ? 22.502 -180.294 6.461 1.00 79.10 ? 206 LYS E CD 1 ATOM 7284 C CE . LYS C 1 148 ? 22.759 -180.591 7.933 1.00 66.46 ? 206 LYS E CE 1 ATOM 7285 N NZ . LYS C 1 148 ? 23.948 -181.471 8.118 1.00 71.89 ? 206 LYS E NZ 1 ATOM 7286 N N . ASN C 1 149 ? 20.988 -183.149 1.521 1.00 36.89 ? 207 ASN E N 1 ATOM 7287 C CA . ASN C 1 149 ? 21.136 -183.218 0.067 1.00 34.47 ? 207 ASN E CA 1 ATOM 7288 C C . ASN C 1 149 ? 19.820 -183.568 -0.622 1.00 37.98 ? 207 ASN E C 1 ATOM 7289 O O . ASN C 1 149 ? 19.807 -183.933 -1.797 1.00 40.36 ? 207 ASN E O 1 ATOM 7290 C CB . ASN C 1 149 ? 22.203 -184.246 -0.315 1.00 40.63 ? 207 ASN E CB 1 ATOM 7291 C CG . ASN C 1 149 ? 23.579 -183.871 0.187 1.00 42.97 ? 207 ASN E CG 1 ATOM 7292 O OD1 . ASN C 1 149 ? 23.953 -182.698 0.194 1.00 40.47 ? 207 ASN E OD1 1 ATOM 7293 N ND2 . ASN C 1 149 ? 24.343 -184.869 0.613 1.00 38.30 ? 207 ASN E ND2 1 ATOM 7294 N N . ASN C 1 150 ? 18.719 -183.451 0.117 1.00 32.35 ? 208 ASN E N 1 ATOM 7295 C CA . ASN C 1 150 ? 17.396 -183.803 -0.394 1.00 38.04 ? 208 ASN E CA 1 ATOM 7296 C C . ASN C 1 150 ? 17.355 -185.243 -0.897 1.00 36.11 ? 208 ASN E C 1 ATOM 7297 O O . ASN C 1 150 ? 16.647 -185.560 -1.854 1.00 41.12 ? 208 ASN E O 1 ATOM 7298 C CB . ASN C 1 150 ? 16.976 -182.846 -1.511 1.00 47.50 ? 208 ASN E CB 1 ATOM 7299 C CG . ASN C 1 150 ? 17.134 -181.390 -1.121 1.00 56.04 ? 208 ASN E CG 1 ATOM 7300 O OD1 . ASN C 1 150 ? 16.346 -180.856 -0.341 1.00 59.65 ? 208 ASN E OD1 1 ATOM 7301 N ND2 . ASN C 1 150 ? 18.154 -180.738 -1.669 1.00 60.20 ? 208 ASN E ND2 1 ATOM 7302 N N . LYS C 1 151 ? 18.126 -186.102 -0.238 1.00 33.99 ? 209 LYS E N 1 ATOM 7303 C CA . LYS C 1 151 ? 18.189 -187.520 -0.565 1.00 35.77 ? 209 LYS E CA 1 ATOM 7304 C C . LYS C 1 151 ? 17.521 -188.340 0.534 1.00 36.06 ? 209 LYS E C 1 ATOM 7305 O O . LYS C 1 151 ? 17.724 -188.085 1.721 1.00 29.80 ? 209 LYS E O 1 ATOM 7306 C CB . LYS C 1 151 ? 19.644 -187.955 -0.755 1.00 41.08 ? 209 LYS E CB 1 ATOM 7307 C CG . LYS C 1 151 ? 19.834 -189.444 -0.976 1.00 55.82 ? 209 LYS E CG 1 ATOM 7308 C CD . LYS C 1 151 ? 21.227 -189.737 -1.511 1.00 71.55 ? 209 LYS E CD 1 ATOM 7309 C CE . LYS C 1 151 ? 21.735 -191.093 -1.050 1.00 81.34 ? 209 LYS E CE 1 ATOM 7310 N NZ . LYS C 1 151 ? 23.000 -191.472 -1.739 1.00 87.05 ? 209 LYS E NZ 1 ATOM 7311 N N . ALA C 1 152 ? 16.720 -189.321 0.129 1.00 31.59 ? 210 ALA E N 1 ATOM 7312 C CA . ALA C 1 152 ? 15.998 -190.163 1.074 1.00 33.39 ? 210 ALA E CA 1 ATOM 7313 C C . ALA C 1 152 ? 16.957 -190.931 1.977 1.00 35.45 ? 210 ALA E C 1 ATOM 7314 O O . ALA C 1 152 ? 18.013 -191.386 1.536 1.00 30.17 ? 210 ALA E O 1 ATOM 7315 C CB . ALA C 1 152 ? 15.087 -191.131 0.329 1.00 34.04 ? 210 ALA E CB 1 ATOM 7316 N N . THR C 1 153 ? 16.579 -191.056 3.245 1.00 29.23 ? 211 THR E N 1 ATOM 7317 C CA . THR C 1 153 ? 17.327 -191.848 4.211 1.00 24.29 ? 211 THR E CA 1 ATOM 7318 C C . THR C 1 153 ? 16.507 -193.077 4.573 1.00 22.03 ? 211 THR E C 1 ATOM 7319 O O . THR C 1 153 ? 15.451 -193.318 3.986 1.00 27.78 ? 211 THR E O 1 ATOM 7320 C CB . THR C 1 153 ? 17.639 -191.052 5.492 1.00 35.63 ? 211 THR E CB 1 ATOM 7321 O OG1 . THR C 1 153 ? 16.430 -190.840 6.235 1.00 24.04 ? 211 THR E OG1 1 ATOM 7322 C CG2 . THR C 1 153 ? 18.275 -189.711 5.155 1.00 30.52 ? 211 THR E CG2 1 ATOM 7323 N N . LYS C 1 154 ? 16.994 -193.845 5.542 1.00 27.22 ? 212 LYS E N 1 ATOM 7324 C CA . LYS C 1 154 ? 16.251 -194.981 6.076 1.00 24.11 ? 212 LYS E CA 1 ATOM 7325 C C . LYS C 1 154 ? 15.744 -194.677 7.489 1.00 24.52 ? 212 LYS E C 1 ATOM 7326 O O . LYS C 1 154 ? 15.367 -195.583 8.231 1.00 27.76 ? 212 LYS E O 1 ATOM 7327 C CB . LYS C 1 154 ? 17.125 -196.237 6.077 1.00 29.44 ? 212 LYS E CB 1 ATOM 7328 C CG . LYS C 1 154 ? 17.459 -196.753 4.684 1.00 37.01 ? 212 LYS E CG 1 ATOM 7329 C CD . LYS C 1 154 ? 18.339 -197.993 4.745 1.00 72.87 ? 212 LYS E CD 1 ATOM 7330 C CE . LYS C 1 154 ? 17.903 -199.039 3.729 1.00 76.96 ? 212 LYS E CE 1 ATOM 7331 N NZ . LYS C 1 154 ? 17.977 -198.539 2.328 1.00 68.95 ? 212 LYS E NZ 1 ATOM 7332 N N . TYR C 1 155 ? 15.735 -193.396 7.848 1.00 24.71 ? 213 TYR E N 1 ATOM 7333 C CA . TYR C 1 155 ? 15.242 -192.959 9.151 1.00 20.90 ? 213 TYR E CA 1 ATOM 7334 C C . TYR C 1 155 ? 13.735 -192.736 9.103 1.00 17.97 ? 213 TYR E C 1 ATOM 7335 O O . TYR C 1 155 ? 13.251 -191.874 8.368 1.00 18.84 ? 213 TYR E O 1 ATOM 7336 C CB . TYR C 1 155 ? 15.953 -191.678 9.585 1.00 24.13 ? 213 TYR E CB 1 ATOM 7337 C CG . TYR C 1 155 ? 15.536 -191.180 10.949 1.00 19.44 ? 213 TYR E CG 1 ATOM 7338 C CD1 . TYR C 1 155 ? 14.453 -190.324 11.095 1.00 24.34 ? 213 TYR E CD1 1 ATOM 7339 C CD2 . TYR C 1 155 ? 16.226 -191.564 12.090 1.00 20.78 ? 213 TYR E CD2 1 ATOM 7340 C CE1 . TYR C 1 155 ? 14.068 -189.866 12.337 1.00 27.68 ? 213 TYR E CE1 1 ATOM 7341 C CE2 . TYR C 1 155 ? 15.849 -191.110 13.339 1.00 25.73 ? 213 TYR E CE2 1 ATOM 7342 C CZ . TYR C 1 155 ? 14.769 -190.260 13.456 1.00 25.58 ? 213 TYR E CZ 1 ATOM 7343 O OH . TYR C 1 155 ? 14.384 -189.800 14.693 1.00 29.24 ? 213 TYR E OH 1 ATOM 7344 N N . ARG C 1 156 ? 13.002 -193.519 9.890 1.00 13.21 ? 214 ARG E N 1 ATOM 7345 C CA . ARG C 1 156 ? 11.543 -193.483 9.881 1.00 15.90 ? 214 ARG E CA 1 ATOM 7346 C C . ARG C 1 156 ? 10.988 -193.083 11.241 1.00 20.10 ? 214 ARG E C 1 ATOM 7347 O O . ARG C 1 156 ? 11.621 -193.306 12.273 1.00 20.16 ? 214 ARG E O 1 ATOM 7348 C CB . ARG C 1 156 ? 10.978 -194.841 9.470 1.00 24.86 ? 214 ARG E CB 1 ATOM 7349 C CG . ARG C 1 156 ? 11.390 -195.276 8.081 1.00 21.36 ? 214 ARG E CG 1 ATOM 7350 C CD . ARG C 1 156 ? 10.804 -196.627 7.732 1.00 21.52 ? 214 ARG E CD 1 ATOM 7351 N NE . ARG C 1 156 ? 10.980 -196.947 6.318 1.00 22.86 ? 214 ARG E NE 1 ATOM 7352 C CZ . ARG C 1 156 ? 12.092 -197.447 5.789 1.00 30.55 ? 214 ARG E CZ 1 ATOM 7353 N NH1 . ARG C 1 156 ? 13.150 -197.691 6.550 1.00 22.62 ? 214 ARG E NH1 1 ATOM 7354 N NH2 . ARG C 1 156 ? 12.147 -197.702 4.489 1.00 32.73 ? 214 ARG E NH2 1 ATOM 7355 N N . TYR C 1 157 ? 9.791 -192.509 11.225 1.00 25.00 ? 215 TYR E N 1 ATOM 7356 C CA . TYR C 1 157 ? 9.176 -191.958 12.422 1.00 16.23 ? 215 TYR E CA 1 ATOM 7357 C C . TYR C 1 157 ? 8.084 -192.874 12.959 1.00 16.37 ? 215 TYR E C 1 ATOM 7358 O O . TYR C 1 157 ? 7.418 -193.561 12.188 1.00 18.37 ? 215 TYR E O 1 ATOM 7359 C CB . TYR C 1 157 ? 8.604 -190.576 12.116 1.00 15.29 ? 215 TYR E CB 1 ATOM 7360 C CG . TYR C 1 157 ? 9.668 -189.574 11.730 1.00 18.88 ? 215 TYR E CG 1 ATOM 7361 C CD1 . TYR C 1 157 ? 10.102 -189.468 10.417 1.00 19.30 ? 215 TYR E CD1 1 ATOM 7362 C CD2 . TYR C 1 157 ? 10.252 -188.751 12.682 1.00 15.87 ? 215 TYR E CD2 1 ATOM 7363 C CE1 . TYR C 1 157 ? 11.080 -188.564 10.060 1.00 26.70 ? 215 TYR E CE1 1 ATOM 7364 C CE2 . TYR C 1 157 ? 11.232 -187.842 12.334 1.00 21.30 ? 215 TYR E CE2 1 ATOM 7365 C CZ . TYR C 1 157 ? 11.642 -187.754 11.019 1.00 22.94 ? 215 TYR E CZ 1 ATOM 7366 O OH . TYR C 1 157 ? 12.617 -186.853 10.660 1.00 32.99 ? 215 TYR E OH 1 ATOM 7367 N N . PRO C 1 158 ? 7.895 -192.894 14.290 1.00 16.93 ? 216 PRO E N 1 ATOM 7368 C CA . PRO C 1 158 ? 6.813 -193.709 14.849 1.00 13.49 ? 216 PRO E CA 1 ATOM 7369 C C . PRO C 1 158 ? 5.444 -193.160 14.496 1.00 21.41 ? 216 PRO E C 1 ATOM 7370 O O . PRO C 1 158 ? 5.331 -192.015 14.059 1.00 16.00 ? 216 PRO E O 1 ATOM 7371 C CB . PRO C 1 158 ? 7.057 -193.638 16.358 1.00 16.24 ? 216 PRO E CB 1 ATOM 7372 C CG . PRO C 1 158 ? 7.827 -192.389 16.561 1.00 15.98 ? 216 PRO E CG 1 ATOM 7373 C CD . PRO C 1 158 ? 8.687 -192.238 15.344 1.00 23.00 ? 216 PRO E CD 1 ATOM 7374 N N . PHE C 1 159 ? 4.420 -193.979 14.693 1.00 14.20 ? 217 PHE E N 1 ATOM 7375 C CA . PHE C 1 159 ? 3.056 -193.599 14.387 1.00 14.08 ? 217 PHE E CA 1 ATOM 7376 C C . PHE C 1 159 ? 2.139 -193.869 15.566 1.00 18.35 ? 217 PHE E C 1 ATOM 7377 O O . PHE C 1 159 ? 2.448 -194.679 16.456 1.00 18.70 ? 217 PHE E O 1 ATOM 7378 C CB . PHE C 1 159 ? 2.551 -194.355 13.153 1.00 16.55 ? 217 PHE E CB 1 ATOM 7379 C CG . PHE C 1 159 ? 2.190 -195.790 13.423 1.00 22.84 ? 217 PHE E CG 1 ATOM 7380 C CD1 . PHE C 1 159 ? 0.903 -196.134 13.805 1.00 19.10 ? 217 PHE E CD1 1 ATOM 7381 C CD2 . PHE C 1 159 ? 3.134 -196.795 13.289 1.00 21.06 ? 217 PHE E CD2 1 ATOM 7382 C CE1 . PHE C 1 159 ? 0.566 -197.451 14.057 1.00 30.62 ? 217 PHE E CE1 1 ATOM 7383 C CE2 . PHE C 1 159 ? 2.802 -198.114 13.538 1.00 22.53 ? 217 PHE E CE2 1 ATOM 7384 C CZ . PHE C 1 159 ? 1.517 -198.442 13.924 1.00 18.62 ? 217 PHE E CZ 1 ATOM 7385 N N . VAL C 1 160 ? 1.009 -193.170 15.553 1.00 15.93 ? 218 VAL E N 1 ATOM 7386 C CA . VAL C 1 160 ? -0.091 -193.443 16.465 1.00 13.56 ? 218 VAL E CA 1 ATOM 7387 C C . VAL C 1 160 ? -1.369 -193.554 15.651 1.00 23.09 ? 218 VAL E C 1 ATOM 7388 O O . VAL C 1 160 ? -1.721 -192.628 14.918 1.00 16.93 ? 218 VAL E O 1 ATOM 7389 C CB . VAL C 1 160 ? -0.262 -192.342 17.531 1.00 14.99 ? 218 VAL E CB 1 ATOM 7390 C CG1 . VAL C 1 160 ? -1.491 -192.621 18.401 1.00 15.21 ? 218 VAL E CG1 1 ATOM 7391 C CG2 . VAL C 1 160 ? 0.983 -192.237 18.392 1.00 17.90 ? 218 VAL E CG2 1 ATOM 7392 N N . TYR C 1 161 ? -2.062 -194.680 15.770 1.00 17.59 ? 219 TYR E N 1 ATOM 7393 C CA . TYR C 1 161 ? -3.366 -194.808 15.139 1.00 13.99 ? 219 TYR E CA 1 ATOM 7394 C C . TYR C 1 161 ? -4.458 -194.536 16.156 1.00 17.42 ? 219 TYR E C 1 ATOM 7395 O O . TYR C 1 161 ? -4.491 -195.137 17.235 1.00 18.74 ? 219 TYR E O 1 ATOM 7396 C CB . TYR C 1 161 ? -3.566 -196.189 14.510 1.00 18.94 ? 219 TYR E CB 1 ATOM 7397 C CG . TYR C 1 161 ? -4.869 -196.283 13.742 1.00 18.49 ? 219 TYR E CG 1 ATOM 7398 C CD1 . TYR C 1 161 ? -5.144 -195.405 12.700 1.00 21.45 ? 219 TYR E CD1 1 ATOM 7399 C CD2 . TYR C 1 161 ? -5.828 -197.235 14.063 1.00 25.00 ? 219 TYR E CD2 1 ATOM 7400 C CE1 . TYR C 1 161 ? -6.330 -195.473 11.999 1.00 22.58 ? 219 TYR E CE1 1 ATOM 7401 C CE2 . TYR C 1 161 ? -7.020 -197.312 13.361 1.00 24.76 ? 219 TYR E CE2 1 ATOM 7402 C CZ . TYR C 1 161 ? -7.264 -196.426 12.330 1.00 26.08 ? 219 TYR E CZ 1 ATOM 7403 O OH . TYR C 1 161 ? -8.444 -196.485 11.622 1.00 24.74 ? 219 TYR E OH 1 ATOM 7404 N N . ASP C 1 162 ? -5.329 -193.596 15.803 1.00 16.04 ? 220 ASP E N 1 ATOM 7405 C CA . ASP C 1 162 ? -6.530 -193.301 16.568 1.00 18.32 ? 220 ASP E CA 1 ATOM 7406 C C . ASP C 1 162 ? -7.698 -193.997 15.886 1.00 21.45 ? 220 ASP E C 1 ATOM 7407 O O . ASP C 1 162 ? -8.200 -193.525 14.856 1.00 19.71 ? 220 ASP E O 1 ATOM 7408 C CB . ASP C 1 162 ? -6.765 -191.792 16.657 1.00 25.73 ? 220 ASP E CB 1 ATOM 7409 C CG . ASP C 1 162 ? -7.901 -191.425 17.599 1.00 26.53 ? 220 ASP E CG 1 ATOM 7410 O OD1 . ASP C 1 162 ? -8.842 -192.230 17.761 1.00 28.10 ? 220 ASP E OD1 1 ATOM 7411 O OD2 . ASP C 1 162 ? -7.855 -190.321 18.179 1.00 31.10 ? 220 ASP E OD2 1 ATOM 7412 N N . SER C 1 163 ? -8.121 -195.116 16.470 1.00 24.71 ? 221 SER E N 1 ATOM 7413 C CA . SER C 1 163 ? -9.117 -195.992 15.858 1.00 24.76 ? 221 SER E CA 1 ATOM 7414 C C . SER C 1 163 ? -10.548 -195.498 16.049 1.00 24.82 ? 221 SER E C 1 ATOM 7415 O O . SER C 1 163 ? -11.439 -195.876 15.290 1.00 33.88 ? 221 SER E O 1 ATOM 7416 C CB . SER C 1 163 ? -8.988 -197.410 16.424 1.00 30.04 ? 221 SER E CB 1 ATOM 7417 O OG . SER C 1 163 ? -9.243 -197.431 17.816 1.00 26.90 ? 221 SER E OG 1 ATOM 7418 N N . LYS C 1 164 ? -10.774 -194.668 17.062 1.00 26.90 ? 222 LYS E N 1 ATOM 7419 C CA . LYS C 1 164 ? -12.098 -194.094 17.273 1.00 29.05 ? 222 LYS E CA 1 ATOM 7420 C C . LYS C 1 164 ? -12.384 -193.051 16.198 1.00 32.23 ? 222 LYS E C 1 ATOM 7421 O O . LYS C 1 164 ? -13.444 -193.058 15.573 1.00 32.75 ? 222 LYS E O 1 ATOM 7422 C CB . LYS C 1 164 ? -12.212 -193.461 18.662 1.00 36.20 ? 222 LYS E CB 1 ATOM 7423 C CG . LYS C 1 164 ? -13.654 -193.184 19.083 1.00 49.80 ? 222 LYS E CG 1 ATOM 7424 C CD . LYS C 1 164 ? -13.825 -191.825 19.755 1.00 61.72 ? 222 LYS E CD 1 ATOM 7425 C CE . LYS C 1 164 ? -13.601 -191.896 21.259 1.00 72.39 ? 222 LYS E CE 1 ATOM 7426 N NZ . LYS C 1 164 ? -14.845 -192.276 21.990 1.00 76.69 ? 222 LYS E NZ 1 ATOM 7427 N N . LYS C 1 165 ? -11.422 -192.158 15.988 1.00 20.36 ? 223 LYS E N 1 ATOM 7428 C CA . LYS C 1 165 ? -11.546 -191.105 14.986 1.00 26.48 ? 223 LYS E CA 1 ATOM 7429 C C . LYS C 1 165 ? -11.098 -191.583 13.604 1.00 24.33 ? 223 LYS E C 1 ATOM 7430 O O . LYS C 1 165 ? -11.307 -190.895 12.604 1.00 32.19 ? 223 LYS E O 1 ATOM 7431 C CB . LYS C 1 165 ? -10.726 -189.886 15.406 1.00 28.42 ? 223 LYS E CB 1 ATOM 7432 C CG . LYS C 1 165 ? -11.312 -189.128 16.587 1.00 32.99 ? 223 LYS E CG 1 ATOM 7433 C CD . LYS C 1 165 ? -10.362 -188.049 17.077 1.00 33.16 ? 223 LYS E CD 1 ATOM 7434 C CE . LYS C 1 165 ? -11.008 -187.193 18.149 1.00 48.06 ? 223 LYS E CE 1 ATOM 7435 N NZ . LYS C 1 165 ? -10.199 -185.981 18.453 1.00 64.61 ? 223 LYS E NZ 1 ATOM 7436 N N . ARG C 1 166 ? -10.487 -192.764 13.560 1.00 29.27 ? 224 ARG E N 1 ATOM 7437 C CA . ARG C 1 166 ? -9.953 -193.328 12.322 1.00 20.93 ? 224 ARG E CA 1 ATOM 7438 C C . ARG C 1 166 ? -8.934 -192.386 11.694 1.00 27.24 ? 224 ARG E C 1 ATOM 7439 O O . ARG C 1 166 ? -9.004 -192.080 10.500 1.00 18.58 ? 224 ARG E O 1 ATOM 7440 C CB . ARG C 1 166 ? -11.081 -193.630 11.333 1.00 25.34 ? 224 ARG E CB 1 ATOM 7441 C CG . ARG C 1 166 ? -12.216 -194.448 11.935 1.00 29.40 ? 224 ARG E CG 1 ATOM 7442 C CD . ARG C 1 166 ? -13.132 -194.995 10.856 1.00 43.72 ? 224 ARG E CD 1 ATOM 7443 N NE . ARG C 1 166 ? -12.485 -196.061 10.091 1.00 41.42 ? 224 ARG E NE 1 ATOM 7444 C CZ . ARG C 1 166 ? -12.556 -196.209 8.769 1.00 47.01 ? 224 ARG E CZ 1 ATOM 7445 N NH1 . ARG C 1 166 ? -13.249 -195.359 8.020 1.00 44.90 ? 224 ARG E NH1 1 ATOM 7446 N NH2 . ARG C 1 166 ? -11.924 -197.219 8.187 1.00 46.98 ? 224 ARG E NH2 1 ATOM 7447 N N . LEU C 1 167 ? -7.982 -191.939 12.511 1.00 19.41 ? 225 LEU E N 1 ATOM 7448 C CA . LEU C 1 167 ? -6.941 -191.025 12.050 1.00 15.49 ? 225 LEU E CA 1 ATOM 7449 C C . LEU C 1 167 ? -5.557 -191.608 12.305 1.00 17.21 ? 225 LEU E C 1 ATOM 7450 O O . LEU C 1 167 ? -5.274 -192.113 13.392 1.00 19.99 ? 225 LEU E O 1 ATOM 7451 C CB . LEU C 1 167 ? -7.063 -189.659 12.739 1.00 21.97 ? 225 LEU E CB 1 ATOM 7452 C CG . LEU C 1 167 ? -8.249 -188.773 12.347 1.00 24.23 ? 225 LEU E CG 1 ATOM 7453 C CD1 . LEU C 1 167 ? -8.293 -187.542 13.237 1.00 25.74 ? 225 LEU E CD1 1 ATOM 7454 C CD2 . LEU C 1 167 ? -8.174 -188.364 10.886 1.00 22.61 ? 225 LEU E CD2 1 ATOM 7455 N N . CYS C 1 168 ? -4.706 -191.530 11.287 1.00 16.72 ? 226 CYS E N 1 ATOM 7456 C CA . CYS C 1 168 ? -3.325 -191.986 11.380 1.00 16.98 ? 226 CYS E CA 1 ATOM 7457 C C . CYS C 1 168 ? -2.396 -190.802 11.654 1.00 21.95 ? 226 CYS E C 1 ATOM 7458 O O . CYS C 1 168 ? -2.390 -189.828 10.903 1.00 23.91 ? 226 CYS E O 1 ATOM 7459 C CB . CYS C 1 168 ? -2.910 -192.701 10.089 1.00 21.25 ? 226 CYS E CB 1 ATOM 7460 S SG . CYS C 1 168 ? -1.266 -193.443 10.154 1.00 42.54 ? 226 CYS E SG 1 ATOM 7461 N N . HIS C 1 169 ? -1.622 -190.892 12.733 1.00 19.28 ? 227 HIS E N 1 ATOM 7462 C CA . HIS C 1 169 ? -0.676 -189.842 13.111 1.00 18.02 ? 227 HIS E CA 1 ATOM 7463 C C . HIS C 1 169 ? 0.764 -190.296 12.924 1.00 19.72 ? 227 HIS E C 1 ATOM 7464 O O . HIS C 1 169 ? 1.140 -191.384 13.367 1.00 25.69 ? 227 HIS E O 1 ATOM 7465 C CB . HIS C 1 169 ? -0.864 -189.424 14.572 1.00 17.01 ? 227 HIS E CB 1 ATOM 7466 C CG . HIS C 1 169 ? -2.237 -188.929 14.900 1.00 18.93 ? 227 HIS E CG 1 ATOM 7467 N ND1 . HIS C 1 169 ? -2.543 -187.588 14.988 1.00 20.35 ? 227 HIS E ND1 1 ATOM 7468 C CD2 . HIS C 1 169 ? -3.380 -189.596 15.186 1.00 18.84 ? 227 HIS E CD2 1 ATOM 7469 C CE1 . HIS C 1 169 ? -3.818 -187.451 15.308 1.00 20.81 ? 227 HIS E CE1 1 ATOM 7470 N NE2 . HIS C 1 169 ? -4.349 -188.653 15.430 1.00 22.82 ? 227 HIS E NE2 1 ATOM 7471 N N . ILE C 1 170 ? 1.564 -189.449 12.284 1.00 14.82 ? 228 ILE E N 1 ATOM 7472 C CA . ILE C 1 170 ? 3.014 -189.615 12.250 1.00 16.42 ? 228 ILE E CA 1 ATOM 7473 C C . ILE C 1 170 ? 3.629 -188.647 13.258 1.00 18.12 ? 228 ILE E C 1 ATOM 7474 O O . ILE C 1 170 ? 3.336 -187.451 13.224 1.00 17.10 ? 228 ILE E O 1 ATOM 7475 C CB . ILE C 1 170 ? 3.599 -189.337 10.853 1.00 15.88 ? 228 ILE E CB 1 ATOM 7476 C CG1 . ILE C 1 170 ? 2.930 -190.215 9.789 1.00 26.83 ? 228 ILE E CG1 1 ATOM 7477 C CG2 . ILE C 1 170 ? 5.113 -189.539 10.860 1.00 15.50 ? 228 ILE E CG2 1 ATOM 7478 C CD1 . ILE C 1 170 ? 3.308 -191.666 9.848 1.00 36.55 ? 228 ILE E CD1 1 ATOM 7479 N N . LEU C 1 171 ? 4.477 -189.155 14.149 1.00 14.07 ? 229 LEU E N 1 ATOM 7480 C CA . LEU C 1 171 ? 5.087 -188.322 15.186 1.00 15.01 ? 229 LEU E CA 1 ATOM 7481 C C . LEU C 1 171 ? 6.476 -187.857 14.773 1.00 21.15 ? 229 LEU E C 1 ATOM 7482 O O . LEU C 1 171 ? 7.347 -188.672 14.489 1.00 27.05 ? 229 LEU E O 1 ATOM 7483 C CB . LEU C 1 171 ? 5.174 -189.081 16.511 1.00 16.44 ? 229 LEU E CB 1 ATOM 7484 C CG . LEU C 1 171 ? 3.870 -189.640 17.077 1.00 18.35 ? 229 LEU E CG 1 ATOM 7485 C CD1 . LEU C 1 171 ? 4.123 -190.234 18.449 1.00 22.27 ? 229 LEU E CD1 1 ATOM 7486 C CD2 . LEU C 1 171 ? 2.787 -188.577 17.146 1.00 19.62 ? 229 LEU E CD2 1 ATOM 7487 N N . TYR C 1 172 ? 6.678 -186.544 14.747 1.00 18.26 ? 230 TYR E N 1 ATOM 7488 C CA . TYR C 1 172 ? 7.981 -185.977 14.422 1.00 12.47 ? 230 TYR E CA 1 ATOM 7489 C C . TYR C 1 172 ? 8.978 -186.228 15.550 1.00 15.95 ? 230 TYR E C 1 ATOM 7490 O O . TYR C 1 172 ? 10.185 -186.303 15.320 1.00 25.58 ? 230 TYR E O 1 ATOM 7491 C CB . TYR C 1 172 ? 7.852 -184.478 14.151 1.00 17.30 ? 230 TYR E CB 1 ATOM 7492 C CG . TYR C 1 172 ? 9.107 -183.831 13.612 1.00 21.61 ? 230 TYR E CG 1 ATOM 7493 C CD1 . TYR C 1 172 ? 9.593 -184.157 12.353 1.00 36.26 ? 230 TYR E CD1 1 ATOM 7494 C CD2 . TYR C 1 172 ? 9.794 -182.880 14.353 1.00 36.30 ? 230 TYR E CD2 1 ATOM 7495 C CE1 . TYR C 1 172 ? 10.735 -183.564 11.853 1.00 37.10 ? 230 TYR E CE1 1 ATOM 7496 C CE2 . TYR C 1 172 ? 10.937 -182.280 13.860 1.00 46.37 ? 230 TYR E CE2 1 ATOM 7497 C CZ . TYR C 1 172 ? 11.402 -182.625 12.608 1.00 41.42 ? 230 TYR E CZ 1 ATOM 7498 O OH . TYR C 1 172 ? 12.540 -182.033 12.109 1.00 55.05 ? 230 TYR E OH 1 ATOM 7499 N N . VAL C 1 173 ? 8.463 -186.352 16.770 1.00 15.80 ? 231 VAL E N 1 ATOM 7500 C CA . VAL C 1 173 ? 9.294 -186.618 17.938 1.00 17.01 ? 231 VAL E CA 1 ATOM 7501 C C . VAL C 1 173 ? 9.299 -188.113 18.247 1.00 17.75 ? 231 VAL E C 1 ATOM 7502 O O . VAL C 1 173 ? 8.251 -188.709 18.496 1.00 18.02 ? 231 VAL E O 1 ATOM 7503 C CB . VAL C 1 173 ? 8.801 -185.831 19.164 1.00 16.83 ? 231 VAL E CB 1 ATOM 7504 C CG1 . VAL C 1 173 ? 9.646 -186.149 20.390 1.00 16.32 ? 231 VAL E CG1 1 ATOM 7505 C CG2 . VAL C 1 173 ? 8.823 -184.332 18.872 1.00 16.35 ? 231 VAL E CG2 1 ATOM 7506 N N . SER C 1 174 ? 10.489 -188.706 18.226 1.00 15.07 ? 232 SER E N 1 ATOM 7507 C CA . SER C 1 174 ? 10.658 -190.131 18.493 1.00 25.52 ? 232 SER E CA 1 ATOM 7508 C C . SER C 1 174 ? 10.998 -190.401 19.954 1.00 22.01 ? 232 SER E C 1 ATOM 7509 O O . SER C 1 174 ? 10.969 -191.548 20.399 1.00 20.75 ? 232 SER E O 1 ATOM 7510 C CB . SER C 1 174 ? 11.750 -190.709 17.595 1.00 21.29 ? 232 SER E CB 1 ATOM 7511 O OG . SER C 1 174 ? 11.397 -190.573 16.230 1.00 30.41 ? 232 SER E OG 1 ATOM 7512 N N . MET C 1 175 ? 11.337 -189.350 20.692 1.00 19.44 ? 233 MET E N 1 ATOM 7513 C CA . MET C 1 175 ? 11.533 -189.471 22.130 1.00 16.33 ? 233 MET E CA 1 ATOM 7514 C C . MET C 1 175 ? 10.241 -189.956 22.776 1.00 14.57 ? 233 MET E C 1 ATOM 7515 O O . MET C 1 175 ? 9.146 -189.659 22.290 1.00 18.37 ? 233 MET E O 1 ATOM 7516 C CB . MET C 1 175 ? 11.967 -188.136 22.742 1.00 14.33 ? 233 MET E CB 1 ATOM 7517 C CG . MET C 1 175 ? 13.324 -187.629 22.265 1.00 20.47 ? 233 MET E CG 1 ATOM 7518 S SD . MET C 1 175 ? 13.905 -186.206 23.214 1.00 22.89 ? 233 MET E SD 1 ATOM 7519 C CE . MET C 1 175 ? 12.665 -184.980 22.798 1.00 26.23 ? 233 MET E CE 1 ATOM 7520 N N . GLN C 1 176 ? 10.376 -190.710 23.863 1.00 17.06 ? 234 GLN E N 1 ATOM 7521 C CA . GLN C 1 176 ? 9.227 -191.275 24.562 1.00 15.00 ? 234 GLN E CA 1 ATOM 7522 C C . GLN C 1 176 ? 9.292 -191.027 26.069 1.00 12.83 ? 234 GLN E C 1 ATOM 7523 O O . GLN C 1 176 ? 8.277 -191.123 26.758 1.00 12.25 ? 234 GLN E O 1 ATOM 7524 C CB . GLN C 1 176 ? 9.132 -192.775 24.272 1.00 19.29 ? 234 GLN E CB 1 ATOM 7525 C CG . GLN C 1 176 ? 8.783 -193.088 22.822 1.00 17.87 ? 234 GLN E CG 1 ATOM 7526 C CD . GLN C 1 176 ? 9.375 -194.398 22.346 1.00 17.25 ? 234 GLN E CD 1 ATOM 7527 O OE1 . GLN C 1 176 ? 8.973 -195.475 22.787 1.00 15.97 ? 234 GLN E OE1 1 ATOM 7528 N NE2 . GLN C 1 176 ? 10.342 -194.313 21.442 1.00 17.93 ? 234 GLN E NE2 1 ATOM 7529 N N . LEU C 1 177 ? 10.476 -190.702 26.578 1.00 12.86 ? 235 LEU E N 1 ATOM 7530 C CA . LEU C 1 177 ? 10.630 -190.380 27.993 1.00 14.91 ? 235 LEU E CA 1 ATOM 7531 C C . LEU C 1 177 ? 11.706 -189.322 28.209 1.00 13.97 ? 235 LEU E C 1 ATOM 7532 O O . LEU C 1 177 ? 12.821 -189.445 27.703 1.00 15.12 ? 235 LEU E O 1 ATOM 7533 C CB . LEU C 1 177 ? 10.972 -191.641 28.793 1.00 19.15 ? 235 LEU E CB 1 ATOM 7534 C CG . LEU C 1 177 ? 10.872 -191.556 30.322 1.00 17.97 ? 235 LEU E CG 1 ATOM 7535 C CD1 . LEU C 1 177 ? 10.756 -192.954 30.902 1.00 33.70 ? 235 LEU E CD1 1 ATOM 7536 C CD2 . LEU C 1 177 ? 12.068 -190.850 30.946 1.00 29.56 ? 235 LEU E CD2 1 ATOM 7537 N N . MET C 1 178 ? 11.363 -188.281 28.963 1.00 15.28 ? 236 MET E N 1 ATOM 7538 C CA . MET C 1 178 ? 12.359 -187.336 29.456 1.00 18.10 ? 236 MET E CA 1 ATOM 7539 C C . MET C 1 178 ? 12.022 -186.956 30.893 1.00 15.57 ? 236 MET E C 1 ATOM 7540 O O . MET C 1 178 ? 10.877 -186.632 31.214 1.00 17.43 ? 236 MET E O 1 ATOM 7541 C CB . MET C 1 178 ? 12.433 -186.088 28.576 1.00 18.75 ? 236 MET E CB 1 ATOM 7542 C CG . MET C 1 178 ? 13.784 -185.384 28.660 1.00 30.00 ? 236 MET E CG 1 ATOM 7543 S SD . MET C 1 178 ? 13.826 -183.778 27.843 1.00 38.10 ? 236 MET E SD 1 ATOM 7544 C CE . MET C 1 178 ? 13.580 -184.246 26.131 1.00 33.16 ? 236 MET E CE 1 ATOM 7545 N N . GLU C 1 179 ? 13.032 -187.010 31.754 1.00 18.05 ? 237 GLU E N 1 ATOM 7546 C CA . GLU C 1 179 ? 12.851 -186.766 33.176 1.00 23.10 ? 237 GLU E CA 1 ATOM 7547 C C . GLU C 1 179 ? 14.113 -186.136 33.746 1.00 19.24 ? 237 GLU E C 1 ATOM 7548 O O . GLU C 1 179 ? 15.181 -186.223 33.141 1.00 24.28 ? 237 GLU E O 1 ATOM 7549 C CB . GLU C 1 179 ? 12.526 -188.072 33.909 1.00 27.57 ? 237 GLU E CB 1 ATOM 7550 C CG . GLU C 1 179 ? 13.728 -188.996 34.076 1.00 36.73 ? 237 GLU E CG 1 ATOM 7551 C CD . GLU C 1 179 ? 13.343 -190.430 34.406 1.00 54.76 ? 237 GLU E CD 1 ATOM 7552 O OE1 . GLU C 1 179 ? 14.164 -191.338 34.153 1.00 53.86 ? 237 GLU E OE1 1 ATOM 7553 O OE2 . GLU C 1 179 ? 12.226 -190.652 34.919 1.00 41.01 ? 237 GLU E OE2 1 ATOM 7554 N N . GLY C 1 180 ? 13.981 -185.500 34.906 1.00 30.90 ? 238 GLY E N 1 ATOM 7555 C CA . GLY C 1 180 ? 15.111 -184.882 35.576 1.00 31.59 ? 238 GLY E CA 1 ATOM 7556 C C . GLY C 1 180 ? 15.136 -183.379 35.388 1.00 32.94 ? 238 GLY E C 1 ATOM 7557 O O . GLY C 1 180 ? 15.072 -182.881 34.264 1.00 23.26 ? 238 GLY E O 1 ATOM 7558 N N . LYS C 1 181 ? 15.245 -182.657 36.499 1.00 24.07 ? 239 LYS E N 1 ATOM 7559 C CA . LYS C 1 181 ? 15.209 -181.199 36.479 1.00 28.67 ? 239 LYS E CA 1 ATOM 7560 C C . LYS C 1 181 ? 16.380 -180.605 35.702 1.00 26.79 ? 239 LYS E C 1 ATOM 7561 O O . LYS C 1 181 ? 16.377 -179.421 35.380 1.00 33.24 ? 239 LYS E O 1 ATOM 7562 C CB . LYS C 1 181 ? 15.204 -180.647 37.909 1.00 34.76 ? 239 LYS E CB 1 ATOM 7563 C CG . LYS C 1 181 ? 16.495 -180.887 38.683 1.00 38.76 ? 239 LYS E CG 1 ATOM 7564 C CD . LYS C 1 181 ? 16.455 -180.219 40.048 0.90 47.45 ? 239 LYS E CD 1 ATOM 7565 C CE . LYS C 1 181 ? 17.680 -180.577 40.876 0.84 43.59 ? 239 LYS E CE 1 ATOM 7566 N NZ . LYS C 1 181 ? 17.699 -182.020 41.248 0.80 60.83 ? 239 LYS E NZ 1 ATOM 7567 N N . LYS C 1 182 ? 17.384 -181.423 35.409 1.00 25.36 ? 240 LYS E N 1 ATOM 7568 C CA . LYS C 1 182 ? 18.527 -180.962 34.634 1.00 27.25 ? 240 LYS E CA 1 ATOM 7569 C C . LYS C 1 182 ? 18.198 -180.915 33.141 1.00 30.35 ? 240 LYS E C 1 ATOM 7570 O O . LYS C 1 182 ? 18.866 -180.218 32.374 1.00 28.20 ? 240 LYS E O 1 ATOM 7571 C CB . LYS C 1 182 ? 19.739 -181.866 34.882 1.00 36.28 ? 240 LYS E CB 1 ATOM 7572 C CG . LYS C 1 182 ? 20.924 -181.570 33.976 1.00 46.40 ? 240 LYS E CG 1 ATOM 7573 C CD . LYS C 1 182 ? 22.239 -182.083 34.550 1.00 57.16 ? 240 LYS E CD 1 ATOM 7574 C CE . LYS C 1 182 ? 22.164 -183.554 34.920 1.00 58.98 ? 240 LYS E CE 1 ATOM 7575 N NZ . LYS C 1 182 ? 23.518 -184.150 35.091 1.00 71.93 ? 240 LYS E NZ 1 ATOM 7576 N N . TYR C 1 183 ? 17.157 -181.640 32.739 1.00 19.25 ? 241 TYR E N 1 ATOM 7577 C CA . TYR C 1 183 ? 16.835 -181.807 31.323 1.00 21.77 ? 241 TYR E CA 1 ATOM 7578 C C . TYR C 1 183 ? 15.478 -181.225 30.933 1.00 19.20 ? 241 TYR E C 1 ATOM 7579 O O . TYR C 1 183 ? 15.299 -180.768 29.805 1.00 20.10 ? 241 TYR E O 1 ATOM 7580 C CB . TYR C 1 183 ? 16.872 -183.292 30.953 1.00 20.36 ? 241 TYR E CB 1 ATOM 7581 C CG . TYR C 1 183 ? 18.206 -183.953 31.225 1.00 29.32 ? 241 TYR E CG 1 ATOM 7582 C CD1 . TYR C 1 183 ? 19.341 -183.589 30.513 1.00 36.14 ? 241 TYR E CD1 1 ATOM 7583 C CD2 . TYR C 1 183 ? 18.328 -184.946 32.189 1.00 33.36 ? 241 TYR E CD2 1 ATOM 7584 C CE1 . TYR C 1 183 ? 20.562 -184.192 30.756 1.00 42.50 ? 241 TYR E CE1 1 ATOM 7585 C CE2 . TYR C 1 183 ? 19.544 -185.556 32.437 1.00 36.18 ? 241 TYR E CE2 1 ATOM 7586 C CZ . TYR C 1 183 ? 20.658 -185.175 31.718 1.00 43.53 ? 241 TYR E CZ 1 ATOM 7587 O OH . TYR C 1 183 ? 21.871 -185.777 31.962 1.00 53.96 ? 241 TYR E OH 1 ATOM 7588 N N . CYS C 1 184 ? 14.522 -181.245 31.854 1.00 21.98 ? 242 CYS E N 1 ATOM 7589 C CA . CYS C 1 184 ? 13.167 -180.821 31.526 1.00 23.85 ? 242 CYS E CA 1 ATOM 7590 C C . CYS C 1 184 ? 12.404 -180.334 32.748 1.00 18.69 ? 242 CYS E C 1 ATOM 7591 O O . CYS C 1 184 ? 12.821 -180.558 33.885 1.00 18.52 ? 242 CYS E O 1 ATOM 7592 C CB . CYS C 1 184 ? 12.404 -181.970 30.863 1.00 19.77 ? 242 CYS E CB 1 ATOM 7593 S SG . CYS C 1 184 ? 12.268 -183.452 31.893 1.00 23.58 ? 242 CYS E SG 1 ATOM 7594 N N . SER C 1 185 ? 11.277 -179.673 32.493 1.00 16.88 ? 243 SER E N 1 ATOM 7595 C CA . SER C 1 185 ? 10.459 -179.081 33.542 1.00 16.56 ? 243 SER E CA 1 ATOM 7596 C C . SER C 1 185 ? 9.137 -179.817 33.719 1.00 14.89 ? 243 SER E C 1 ATOM 7597 O O . SER C 1 185 ? 8.569 -180.335 32.759 1.00 15.41 ? 243 SER E O 1 ATOM 7598 C CB . SER C 1 185 ? 10.182 -177.612 33.223 1.00 21.99 ? 243 SER E CB 1 ATOM 7599 O OG . SER C 1 185 ? 9.454 -177.489 32.010 1.00 23.68 ? 243 SER E OG 1 ATOM 7600 N N . VAL C 1 186 ? 8.659 -179.843 34.959 1.00 17.90 ? 244 VAL E N 1 ATOM 7601 C CA . VAL C 1 186 ? 7.354 -180.398 35.295 1.00 16.58 ? 244 VAL E CA 1 ATOM 7602 C C . VAL C 1 186 ? 6.386 -179.259 35.580 1.00 18.16 ? 244 VAL E C 1 ATOM 7603 O O . VAL C 1 186 ? 6.549 -178.530 36.557 1.00 19.54 ? 244 VAL E O 1 ATOM 7604 C CB . VAL C 1 186 ? 7.437 -181.332 36.520 1.00 20.04 ? 244 VAL E CB 1 ATOM 7605 C CG1 . VAL C 1 186 ? 6.046 -181.733 37.001 1.00 23.46 ? 244 VAL E CG1 1 ATOM 7606 C CG2 . VAL C 1 186 ? 8.256 -182.566 36.185 1.00 24.31 ? 244 VAL E CG2 1 ATOM 7607 N N . LYS C 1 187 ? 5.383 -179.114 34.720 1.00 21.72 ? 245 LYS E N 1 ATOM 7608 C CA . LYS C 1 187 ? 4.396 -178.044 34.840 1.00 22.48 ? 245 LYS E CA 1 ATOM 7609 C C . LYS C 1 187 ? 5.052 -176.673 35.028 1.00 27.19 ? 245 LYS E C 1 ATOM 7610 O O . LYS C 1 187 ? 4.587 -175.855 35.823 1.00 25.79 ? 245 LYS E O 1 ATOM 7611 C CB . LYS C 1 187 ? 3.439 -178.335 35.999 1.00 27.63 ? 245 LYS E CB 1 ATOM 7612 C CG . LYS C 1 187 ? 2.583 -179.582 35.799 1.00 29.86 ? 245 LYS E CG 1 ATOM 7613 C CD . LYS C 1 187 ? 1.631 -179.785 36.967 1.00 45.40 ? 245 LYS E CD 1 ATOM 7614 C CE . LYS C 1 187 ? 0.902 -181.116 36.884 1.00 61.23 ? 245 LYS E CE 1 ATOM 7615 N NZ . LYS C 1 187 ? -0.111 -181.138 35.796 1.00 53.99 ? 245 LYS E NZ 1 ATOM 7616 N N . GLY C 1 188 ? 6.141 -176.437 34.299 1.00 21.93 ? 246 GLY E N 1 ATOM 7617 C CA . GLY C 1 188 ? 6.791 -175.137 34.279 1.00 22.64 ? 246 GLY E CA 1 ATOM 7618 C C . GLY C 1 188 ? 7.965 -174.965 35.231 1.00 23.74 ? 246 GLY E C 1 ATOM 7619 O O . GLY C 1 188 ? 8.631 -173.930 35.190 1.00 25.91 ? 246 GLY E O 1 ATOM 7620 N N . GLU C 1 189 ? 8.223 -175.962 36.078 1.00 24.33 ? 247 GLU E N 1 ATOM 7621 C CA . GLU C 1 189 ? 9.321 -175.898 37.043 1.00 25.29 ? 247 GLU E CA 1 ATOM 7622 C C . GLU C 1 189 ? 10.458 -176.844 36.658 1.00 26.43 ? 247 GLU E C 1 ATOM 7623 O O . GLU C 1 189 ? 10.250 -178.053 36.567 1.00 24.21 ? 247 GLU E O 1 ATOM 7624 C CB . GLU C 1 189 ? 8.810 -176.237 38.447 1.00 28.80 ? 247 GLU E CB 1 ATOM 7625 C CG . GLU C 1 189 ? 9.900 -176.369 39.514 1.00 33.04 ? 247 GLU E CG 1 ATOM 7626 C CD . GLU C 1 189 ? 10.699 -175.094 39.709 1.00 35.48 ? 247 GLU E CD 1 ATOM 7627 O OE1 . GLU C 1 189 ? 11.835 -175.177 40.224 1.00 39.04 ? 247 GLU E OE1 1 ATOM 7628 O OE2 . GLU C 1 189 ? 10.192 -174.008 39.357 1.00 41.71 ? 247 GLU E OE2 1 ATOM 7629 N N . PRO C 1 190 ? 11.675 -176.307 36.446 1.00 25.93 ? 248 PRO E N 1 ATOM 7630 C CA . PRO C 1 190 ? 12.137 -174.913 36.485 1.00 31.50 ? 248 PRO E CA 1 ATOM 7631 C C . PRO C 1 190 ? 11.803 -174.168 35.193 1.00 33.96 ? 248 PRO E C 1 ATOM 7632 O O . PRO C 1 190 ? 11.798 -174.783 34.127 1.00 32.87 ? 248 PRO E O 1 ATOM 7633 C CB . PRO C 1 190 ? 13.648 -175.052 36.674 1.00 24.98 ? 248 PRO E CB 1 ATOM 7634 C CG . PRO C 1 190 ? 13.982 -176.337 36.044 1.00 32.75 ? 248 PRO E CG 1 ATOM 7635 C CD . PRO C 1 190 ? 12.799 -177.240 36.253 1.00 30.37 ? 248 PRO E CD 1 ATOM 7636 N N . PRO C 1 191 ? 11.537 -172.856 35.282 1.00 36.69 ? 249 PRO E N 1 ATOM 7637 C CA . PRO C 1 191 ? 11.047 -172.091 34.128 1.00 31.76 ? 249 PRO E CA 1 ATOM 7638 C C . PRO C 1 191 ? 12.106 -171.818 33.058 1.00 24.78 ? 249 PRO E C 1 ATOM 7639 O O . PRO C 1 191 ? 11.764 -171.337 31.979 1.00 28.87 ? 249 PRO E O 1 ATOM 7640 C CB . PRO C 1 191 ? 10.577 -170.781 34.762 1.00 43.60 ? 249 PRO E CB 1 ATOM 7641 C CG . PRO C 1 191 ? 11.445 -170.617 35.962 1.00 39.98 ? 249 PRO E CG 1 ATOM 7642 C CD . PRO C 1 191 ? 11.723 -172.004 36.471 1.00 33.21 ? 249 PRO E CD 1 ATOM 7643 N N . ASP C 1 192 ? 13.365 -172.130 33.351 1.00 26.49 ? 250 ASP E N 1 ATOM 7644 C CA . ASP C 1 192 ? 14.466 -171.824 32.439 1.00 30.04 ? 250 ASP E CA 1 ATOM 7645 C C . ASP C 1 192 ? 14.602 -172.836 31.298 1.00 31.14 ? 250 ASP E C 1 ATOM 7646 O O . ASP C 1 192 ? 15.325 -172.590 30.332 1.00 26.55 ? 250 ASP E O 1 ATOM 7647 C CB . ASP C 1 192 ? 15.788 -171.764 33.212 1.00 34.77 ? 250 ASP E CB 1 ATOM 7648 C CG . ASP C 1 192 ? 15.823 -170.642 34.239 1.00 67.67 ? 250 ASP E CG 1 ATOM 7649 O OD1 . ASP C 1 192 ? 15.466 -169.498 33.892 1.00 62.52 ? 250 ASP E OD1 1 ATOM 7650 O OD2 . ASP C 1 192 ? 16.213 -170.903 35.398 1.00 57.30 ? 250 ASP E OD2 1 ATOM 7651 N N . LEU C 1 193 ? 13.912 -173.967 31.408 1.00 26.05 ? 251 LEU E N 1 ATOM 7652 C CA . LEU C 1 193 ? 14.144 -175.087 30.499 1.00 24.13 ? 251 LEU E CA 1 ATOM 7653 C C . LEU C 1 193 ? 13.225 -175.105 29.284 1.00 17.62 ? 251 LEU E C 1 ATOM 7654 O O . LEU C 1 193 ? 12.045 -174.763 29.360 1.00 20.66 ? 251 LEU E O 1 ATOM 7655 C CB . LEU C 1 193 ? 13.999 -176.406 31.253 1.00 19.81 ? 251 LEU E CB 1 ATOM 7656 C CG . LEU C 1 193 ? 15.025 -176.638 32.364 1.00 27.63 ? 251 LEU E CG 1 ATOM 7657 C CD1 . LEU C 1 193 ? 14.740 -177.950 33.047 1.00 25.42 ? 251 LEU E CD1 1 ATOM 7658 C CD2 . LEU C 1 193 ? 16.454 -176.621 31.837 1.00 34.44 ? 251 LEU E CD2 1 ATOM 7659 N N . THR C 1 194 ? 13.794 -175.530 28.165 1.00 16.97 ? 252 THR E N 1 ATOM 7660 C CA . THR C 1 194 ? 13.076 -175.634 26.907 1.00 22.82 ? 252 THR E CA 1 ATOM 7661 C C . THR C 1 194 ? 12.055 -176.767 26.933 1.00 24.87 ? 252 THR E C 1 ATOM 7662 O O . THR C 1 194 ? 10.887 -176.576 26.588 1.00 20.18 ? 252 THR E O 1 ATOM 7663 C CB . THR C 1 194 ? 14.061 -175.865 25.749 1.00 23.83 ? 252 THR E CB 1 ATOM 7664 O OG1 . THR C 1 194 ? 14.958 -174.753 25.662 1.00 29.48 ? 252 THR E OG1 1 ATOM 7665 C CG2 . THR C 1 194 ? 13.332 -176.027 24.424 1.00 23.37 ? 252 THR E CG2 1 ATOM 7666 N N . TRP C 1 195 ? 12.506 -177.947 27.343 1.00 19.26 ? 253 TRP E N 1 ATOM 7667 C CA . TRP C 1 195 ? 11.671 -179.140 27.288 1.00 16.01 ? 253 TRP E CA 1 ATOM 7668 C C . TRP C 1 195 ? 10.820 -179.335 28.534 1.00 13.93 ? 253 TRP E C 1 ATOM 7669 O O . TRP C 1 195 ? 11.277 -179.158 29.661 1.00 15.73 ? 253 TRP E O 1 ATOM 7670 C CB . TRP C 1 195 ? 12.541 -180.380 27.061 1.00 21.28 ? 253 TRP E CB 1 ATOM 7671 C CG . TRP C 1 195 ? 12.919 -180.570 25.626 1.00 23.22 ? 253 TRP E CG 1 ATOM 7672 C CD1 . TRP C 1 195 ? 14.117 -180.271 25.043 1.00 25.21 ? 253 TRP E CD1 1 ATOM 7673 C CD2 . TRP C 1 195 ? 12.085 -181.092 24.584 1.00 15.80 ? 253 TRP E CD2 1 ATOM 7674 N NE1 . TRP C 1 195 ? 14.080 -180.579 23.703 1.00 26.68 ? 253 TRP E NE1 1 ATOM 7675 C CE2 . TRP C 1 195 ? 12.844 -181.084 23.397 1.00 18.71 ? 253 TRP E CE2 1 ATOM 7676 C CE3 . TRP C 1 195 ? 10.770 -181.566 24.542 1.00 21.00 ? 253 TRP E CE3 1 ATOM 7677 C CZ2 . TRP C 1 195 ? 12.331 -181.532 22.181 1.00 25.04 ? 253 TRP E CZ2 1 ATOM 7678 C CZ3 . TRP C 1 195 ? 10.264 -182.011 23.334 1.00 20.46 ? 253 TRP E CZ3 1 ATOM 7679 C CH2 . TRP C 1 195 ? 11.043 -181.991 22.170 1.00 19.93 ? 253 TRP E CH2 1 ATOM 7680 N N . TYR C 1 196 ? 9.561 -179.677 28.300 1.00 12.00 ? 254 TYR E N 1 ATOM 7681 C CA . TYR C 1 196 ? 8.696 -180.229 29.331 1.00 15.96 ? 254 TYR E CA 1 ATOM 7682 C C . TYR C 1 196 ? 9.037 -181.704 29.482 1.00 18.42 ? 254 TYR E C 1 ATOM 7683 O O . TYR C 1 196 ? 9.499 -182.337 28.530 1.00 17.68 ? 254 TYR E O 1 ATOM 7684 C CB . TYR C 1 196 ? 7.222 -180.059 28.964 1.00 15.25 ? 254 TYR E CB 1 ATOM 7685 C CG . TYR C 1 196 ? 6.915 -180.510 27.554 1.00 15.20 ? 254 TYR E CG 1 ATOM 7686 C CD1 . TYR C 1 196 ? 6.717 -181.852 27.259 1.00 15.12 ? 254 TYR E CD1 1 ATOM 7687 C CD2 . TYR C 1 196 ? 6.845 -179.594 26.512 1.00 16.95 ? 254 TYR E CD2 1 ATOM 7688 C CE1 . TYR C 1 196 ? 6.454 -182.268 25.971 1.00 17.46 ? 254 TYR E CE1 1 ATOM 7689 C CE2 . TYR C 1 196 ? 6.577 -180.002 25.218 1.00 13.11 ? 254 TYR E CE2 1 ATOM 7690 C CZ . TYR C 1 196 ? 6.381 -181.342 24.955 1.00 16.72 ? 254 TYR E CZ 1 ATOM 7691 O OH . TYR C 1 196 ? 6.115 -181.761 23.672 1.00 15.88 ? 254 TYR E OH 1 ATOM 7692 N N . CYS C 1 197 ? 8.815 -182.250 30.670 1.00 14.51 ? 255 CYS E N 1 ATOM 7693 C CA . CYS C 1 197 ? 9.010 -183.675 30.899 1.00 18.74 ? 255 CYS E CA 1 ATOM 7694 C C . CYS C 1 197 ? 7.838 -184.466 30.341 1.00 19.76 ? 255 CYS E C 1 ATOM 7695 O O . CYS C 1 197 ? 6.732 -183.947 30.197 1.00 13.89 ? 255 CYS E O 1 ATOM 7696 C CB . CYS C 1 197 ? 9.179 -183.960 32.391 1.00 22.40 ? 255 CYS E CB 1 ATOM 7697 S SG . CYS C 1 197 ? 10.655 -183.195 33.106 1.00 31.14 ? 255 CYS E SG 1 ATOM 7698 N N . PHE C 1 198 ? 8.088 -185.727 30.015 1.00 12.28 ? 256 PHE E N 1 ATOM 7699 C CA . PHE C 1 198 ? 7.030 -186.592 29.522 1.00 13.24 ? 256 PHE E CA 1 ATOM 7700 C C . PHE C 1 198 ? 7.397 -188.053 29.696 1.00 13.99 ? 256 PHE E C 1 ATOM 7701 O O . PHE C 1 198 ? 8.568 -188.390 29.892 1.00 13.93 ? 256 PHE E O 1 ATOM 7702 C CB . PHE C 1 198 ? 6.733 -186.297 28.048 1.00 12.01 ? 256 PHE E CB 1 ATOM 7703 C CG . PHE C 1 198 ? 7.947 -186.315 27.162 1.00 15.46 ? 256 PHE E CG 1 ATOM 7704 C CD1 . PHE C 1 198 ? 8.400 -187.501 26.610 1.00 16.96 ? 256 PHE E CD1 1 ATOM 7705 C CD2 . PHE C 1 198 ? 8.628 -185.143 26.871 1.00 14.20 ? 256 PHE E CD2 1 ATOM 7706 C CE1 . PHE C 1 198 ? 9.513 -187.522 25.789 1.00 11.90 ? 256 PHE E CE1 1 ATOM 7707 C CE2 . PHE C 1 198 ? 9.742 -185.156 26.050 1.00 13.10 ? 256 PHE E CE2 1 ATOM 7708 C CZ . PHE C 1 198 ? 10.185 -186.346 25.509 1.00 19.11 ? 256 PHE E CZ 1 ATOM 7709 N N . LYS C 1 199 ? 6.395 -188.923 29.637 1.00 15.00 ? 257 LYS E N 1 ATOM 7710 C CA . LYS C 1 199 ? 6.667 -190.356 29.727 1.00 16.42 ? 257 LYS E CA 1 ATOM 7711 C C . LYS C 1 199 ? 5.533 -191.198 29.156 1.00 13.60 ? 257 LYS E C 1 ATOM 7712 O O . LYS C 1 199 ? 4.402 -190.727 29.040 1.00 15.28 ? 257 LYS E O 1 ATOM 7713 C CB . LYS C 1 199 ? 6.925 -190.765 31.182 1.00 17.03 ? 257 LYS E CB 1 ATOM 7714 C CG . LYS C 1 199 ? 5.728 -190.594 32.101 1.00 20.75 ? 257 LYS E CG 1 ATOM 7715 C CD . LYS C 1 199 ? 6.064 -190.987 33.534 1.00 32.01 ? 257 LYS E CD 1 ATOM 7716 C CE . LYS C 1 199 ? 4.895 -190.732 34.472 1.00 46.44 ? 257 LYS E CE 1 ATOM 7717 N NZ . LYS C 1 199 ? 5.128 -191.300 35.833 1.00 51.82 ? 257 LYS E NZ 1 ATOM 7718 N N . PRO C 1 200 ? 5.832 -192.458 28.802 1.00 13.79 ? 258 PRO E N 1 ATOM 7719 C CA . PRO C 1 200 ? 4.777 -193.324 28.273 1.00 11.94 ? 258 PRO E CA 1 ATOM 7720 C C . PRO C 1 200 ? 3.789 -193.729 29.355 1.00 15.21 ? 258 PRO E C 1 ATOM 7721 O O . PRO C 1 200 ? 4.192 -193.959 30.493 1.00 18.71 ? 258 PRO E O 1 ATOM 7722 C CB . PRO C 1 200 ? 5.544 -194.547 27.752 1.00 12.71 ? 258 PRO E CB 1 ATOM 7723 C CG . PRO C 1 200 ? 6.988 -194.158 27.757 1.00 14.30 ? 258 PRO E CG 1 ATOM 7724 C CD . PRO C 1 200 ? 7.126 -193.158 28.848 1.00 13.46 ? 258 PRO E CD 1 ATOM 7725 N N . ARG C 1 201 ? 2.525 -193.846 29.020 1.00 17.54 ? 259 ARG E N 1 ATOM 7726 C CA . ARG C 1 201 ? 1.514 -194.290 29.956 1.00 16.54 ? 259 ARG E CA 1 ATOM 7727 C C . ARG C 1 201 ? 0.452 -195.115 29.260 1.00 19.11 ? 259 ARG E C 1 ATOM 7728 O O . ARG C 1 201 ? 0.266 -195.008 28.071 1.00 16.62 ? 259 ARG E O 1 ATOM 7729 C CB . ARG C 1 201 ? 0.768 -193.120 30.612 1.00 18.28 ? 259 ARG E CB 1 ATOM 7730 C CG . ARG C 1 201 ? 1.556 -192.181 31.506 1.00 28.13 ? 259 ARG E CG 1 ATOM 7731 C CD . ARG C 1 201 ? 1.887 -192.801 32.847 1.00 25.66 ? 259 ARG E CD 1 ATOM 7732 N NE . ARG C 1 201 ? 3.129 -193.548 32.767 1.00 49.78 ? 259 ARG E NE 1 ATOM 7733 C CZ . ARG C 1 201 ? 3.708 -194.184 33.775 1.00 44.13 ? 259 ARG E CZ 1 ATOM 7734 N NH1 . ARG C 1 201 ? 4.837 -194.826 33.574 1.00 34.56 ? 259 ARG E NH1 1 ATOM 7735 N NH2 . ARG C 1 201 ? 3.162 -194.171 34.978 1.00 46.54 ? 259 ARG E NH2 1 ATOM 7736 N N . LYS C 1 202 ? -0.238 -195.922 30.056 1.00 13.65 ? 260 LYS E N 1 ATOM 7737 C CA . LYS C 1 202 ? -1.417 -196.670 29.695 1.00 15.76 ? 260 LYS E CA 1 ATOM 7738 C C . LYS C 1 202 ? -2.358 -196.275 30.829 1.00 15.66 ? 260 LYS E C 1 ATOM 7739 O O . LYS C 1 202 ? -1.923 -196.106 31.939 1.00 21.12 ? 260 LYS E O 1 ATOM 7740 C CB . LYS C 1 202 ? -1.204 -198.171 29.591 1.00 13.00 ? 260 LYS E CB 1 ATOM 7741 C CG . LYS C 1 202 ? -0.551 -198.591 28.304 1.00 16.35 ? 260 LYS E CG 1 ATOM 7742 C CD . LYS C 1 202 ? -0.765 -200.050 28.006 1.00 18.56 ? 260 LYS E CD 1 ATOM 7743 C CE . LYS C 1 202 ? 0.238 -200.533 26.996 1.00 13.01 ? 260 LYS E CE 1 ATOM 7744 N NZ . LYS C 1 202 ? -0.216 -201.780 26.359 1.00 21.42 ? 260 LYS E NZ 1 ATOM 7745 N N . SER C 1 203 ? -3.633 -196.109 30.535 1.00 22.06 ? 261 SER E N 1 ATOM 7746 C CA . SER C 1 203 ? -4.610 -195.655 31.518 1.00 20.49 ? 261 SER E CA 1 ATOM 7747 C C . SER C 1 203 ? -5.774 -196.629 31.643 1.00 25.94 ? 261 SER E C 1 ATOM 7748 O O . SER C 1 203 ? -6.196 -197.234 30.660 1.00 22.12 ? 261 SER E O 1 ATOM 7749 C CB . SER C 1 203 ? -5.132 -194.271 31.137 1.00 27.22 ? 261 SER E CB 1 ATOM 7750 O OG . SER C 1 203 ? -6.301 -193.951 31.868 1.00 32.16 ? 261 SER E OG 1 ATOM 7751 N N . VAL C 1 204 ? -6.299 -196.771 32.855 1.00 24.20 ? 262 VAL E N 1 ATOM 7752 C CA . VAL C 1 204 ? -7.391 -197.704 33.096 1.00 27.87 ? 262 VAL E CA 1 ATOM 7753 C C . VAL C 1 204 ? -8.676 -197.270 32.388 1.00 31.13 ? 262 VAL E C 1 ATOM 7754 O O . VAL C 1 204 ? -9.553 -198.097 32.137 1.00 40.08 ? 262 VAL E O 1 ATOM 7755 C CB . VAL C 1 204 ? -7.673 -197.869 34.608 1.00 32.53 ? 262 VAL E CB 1 ATOM 7756 C CG1 . VAL C 1 204 ? -6.477 -198.505 35.305 1.00 33.21 ? 262 VAL E CG1 1 ATOM 7757 C CG2 . VAL C 1 204 ? -8.022 -196.533 35.250 1.00 38.53 ? 262 VAL E CG2 1 ATOM 7758 N N . THR C 1 205 ? -8.777 -195.981 32.059 1.00 29.74 ? 263 THR E N 1 ATOM 7759 C CA . THR C 1 205 ? -9.974 -195.439 31.410 1.00 42.45 ? 263 THR E CA 1 ATOM 7760 C C . THR C 1 205 ? -9.700 -194.717 30.083 1.00 33.59 ? 263 THR E C 1 ATOM 7761 O O . THR C 1 205 ? -10.511 -194.795 29.160 1.00 35.79 ? 263 THR E O 1 ATOM 7762 C CB . THR C 1 205 ? -10.706 -194.449 32.341 1.00 40.95 ? 263 THR E CB 1 ATOM 7763 O OG1 . THR C 1 205 ? -9.771 -193.498 32.864 1.00 44.97 ? 263 THR E OG1 1 ATOM 7764 C CG2 . THR C 1 205 ? -11.380 -195.185 33.496 1.00 46.51 ? 263 THR E CG2 1 ATOM 7765 N N . GLU C 1 206 ? -8.570 -194.021 29.988 1.00 32.33 ? 264 GLU E N 1 ATOM 7766 C CA . GLU C 1 206 ? -8.310 -193.134 28.851 1.00 32.64 ? 264 GLU E CA 1 ATOM 7767 C C . GLU C 1 206 ? -7.458 -193.769 27.753 1.00 29.69 ? 264 GLU E C 1 ATOM 7768 O O . GLU C 1 206 ? -6.591 -194.602 28.020 1.00 23.31 ? 264 GLU E O 1 ATOM 7769 C CB . GLU C 1 206 ? -7.615 -191.850 29.324 1.00 32.80 ? 264 GLU E CB 1 ATOM 7770 C CG . GLU C 1 206 ? -8.228 -191.196 30.555 1.00 47.50 ? 264 GLU E CG 1 ATOM 7771 C CD . GLU C 1 206 ? -9.669 -190.766 30.347 1.00 60.42 ? 264 GLU E CD 1 ATOM 7772 O OE1 . GLU C 1 206 ? -10.386 -190.585 31.355 1.00 81.53 ? 264 GLU E OE1 1 ATOM 7773 O OE2 . GLU C 1 206 ? -10.083 -190.597 29.181 1.00 73.82 ? 264 GLU E OE2 1 ATOM 7774 N N . ASN C 1 207 ? -7.730 -193.360 26.517 1.00 25.12 ? 265 ASN E N 1 ATOM 7775 C CA . ASN C 1 207 ? -6.851 -193.614 25.375 1.00 22.18 ? 265 ASN E CA 1 ATOM 7776 C C . ASN C 1 207 ? -6.619 -195.085 25.037 1.00 19.97 ? 265 ASN E C 1 ATOM 7777 O O . ASN C 1 207 ? -5.546 -195.453 24.560 1.00 22.28 ? 265 ASN E O 1 ATOM 7778 C CB . ASN C 1 207 ? -5.499 -192.937 25.614 1.00 23.34 ? 265 ASN E CB 1 ATOM 7779 C CG . ASN C 1 207 ? -5.620 -191.434 25.757 1.00 29.53 ? 265 ASN E CG 1 ATOM 7780 O OD1 . ASN C 1 207 ? -6.368 -190.789 25.023 1.00 33.80 ? 265 ASN E OD1 1 ATOM 7781 N ND2 . ASN C 1 207 ? -4.889 -190.869 26.709 1.00 38.53 ? 265 ASN E ND2 1 ATOM 7782 N N . HIS C 1 208 ? -7.624 -195.924 25.260 1.00 21.69 ? 266 HIS E N 1 ATOM 7783 C CA . HIS C 1 208 ? -7.524 -197.329 24.874 1.00 30.51 ? 266 HIS E CA 1 ATOM 7784 C C . HIS C 1 208 ? -7.539 -197.473 23.356 1.00 30.44 ? 266 HIS E C 1 ATOM 7785 O O . HIS C 1 208 ? -7.008 -198.435 22.803 1.00 31.01 ? 266 HIS E O 1 ATOM 7786 C CB . HIS C 1 208 ? -8.670 -198.138 25.482 1.00 31.97 ? 266 HIS E CB 1 ATOM 7787 C CG . HIS C 1 208 ? -8.670 -198.156 26.978 1.00 26.40 ? 266 HIS E CG 1 ATOM 7788 N ND1 . HIS C 1 208 ? -9.752 -198.583 27.716 1.00 26.73 ? 266 HIS E ND1 1 ATOM 7789 C CD2 . HIS C 1 208 ? -7.720 -197.800 27.874 1.00 29.66 ? 266 HIS E CD2 1 ATOM 7790 C CE1 . HIS C 1 208 ? -9.470 -198.487 29.003 1.00 32.69 ? 266 HIS E CE1 1 ATOM 7791 N NE2 . HIS C 1 208 ? -8.243 -198.014 29.126 1.00 30.27 ? 266 HIS E NE2 1 ATOM 7792 N N . HIS C 1 209 ? -8.146 -196.493 22.696 1.00 25.23 ? 267 HIS E N 1 ATOM 7793 C CA A HIS C 1 209 ? -8.335 -196.482 21.250 0.47 28.08 ? 267 HIS E CA 1 ATOM 7794 C CA B HIS C 1 209 ? -8.309 -196.557 21.248 0.53 28.05 ? 267 HIS E CA 1 ATOM 7795 C C . HIS C 1 209 ? -7.098 -195.998 20.500 1.00 24.66 ? 267 HIS E C 1 ATOM 7796 O O . HIS C 1 209 ? -7.076 -195.988 19.270 1.00 27.03 ? 267 HIS E O 1 ATOM 7797 C CB A HIS C 1 209 ? -9.530 -195.591 20.892 0.47 30.53 ? 267 HIS E CB 1 ATOM 7798 C CB B HIS C 1 209 ? -9.584 -195.820 20.842 0.53 30.11 ? 267 HIS E CB 1 ATOM 7799 C CG A HIS C 1 209 ? -9.429 -194.199 21.438 0.47 38.11 ? 267 HIS E CG 1 ATOM 7800 C CG B HIS C 1 209 ? -10.818 -196.360 21.497 0.53 30.98 ? 267 HIS E CG 1 ATOM 7801 N ND1 A HIS C 1 209 ? -9.637 -193.903 22.769 0.47 27.16 ? 267 HIS E ND1 1 ATOM 7802 N ND1 B HIS C 1 209 ? -10.952 -197.688 21.842 0.53 36.60 ? 267 HIS E ND1 1 ATOM 7803 C CD2 A HIS C 1 209 ? -9.136 -193.022 20.835 0.47 31.70 ? 267 HIS E CD2 1 ATOM 7804 C CD2 B HIS C 1 209 ? -11.965 -195.753 21.884 0.53 32.79 ? 267 HIS E CD2 1 ATOM 7805 C CE1 A HIS C 1 209 ? -9.478 -192.607 22.961 0.47 36.68 ? 267 HIS E CE1 1 ATOM 7806 C CE1 B HIS C 1 209 ? -12.131 -197.877 22.406 0.53 38.08 ? 267 HIS E CE1 1 ATOM 7807 N NE2 A HIS C 1 209 ? -9.174 -192.048 21.803 0.47 37.30 ? 267 HIS E NE2 1 ATOM 7808 N NE2 B HIS C 1 209 ? -12.765 -196.719 22.444 0.53 42.06 ? 267 HIS E NE2 1 ATOM 7809 N N . LEU C 1 210 ? -6.080 -195.564 21.242 1.00 17.10 ? 268 LEU E N 1 ATOM 7810 C CA . LEU C 1 210 ? -4.826 -195.123 20.635 1.00 16.65 ? 268 LEU E CA 1 ATOM 7811 C C . LEU C 1 210 ? -3.852 -196.289 20.548 1.00 20.93 ? 268 LEU E C 1 ATOM 7812 O O . LEU C 1 210 ? -3.686 -197.038 21.515 1.00 20.18 ? 268 LEU E O 1 ATOM 7813 C CB . LEU C 1 210 ? -4.193 -193.979 21.432 1.00 15.95 ? 268 LEU E CB 1 ATOM 7814 C CG . LEU C 1 210 ? -5.001 -192.688 21.584 1.00 22.89 ? 268 LEU E CG 1 ATOM 7815 C CD1 . LEU C 1 210 ? -4.160 -191.639 22.300 1.00 23.10 ? 268 LEU E CD1 1 ATOM 7816 C CD2 . LEU C 1 210 ? -5.480 -192.164 20.237 1.00 20.11 ? 268 LEU E CD2 1 ATOM 7817 N N . ILE C 1 211 ? -3.221 -196.445 19.387 1.00 15.84 ? 269 ILE E N 1 ATOM 7818 C CA . ILE C 1 211 ? -2.227 -197.496 19.186 1.00 16.25 ? 269 ILE E CA 1 ATOM 7819 C C . ILE C 1 211 ? -0.897 -196.916 18.710 1.00 16.73 ? 269 ILE E C 1 ATOM 7820 O O . ILE C 1 211 ? -0.804 -196.363 17.614 1.00 19.72 ? 269 ILE E O 1 ATOM 7821 C CB . ILE C 1 211 ? -2.727 -198.541 18.173 1.00 18.33 ? 269 ILE E CB 1 ATOM 7822 C CG1 . ILE C 1 211 ? -3.986 -199.227 18.705 1.00 22.67 ? 269 ILE E CG1 1 ATOM 7823 C CG2 . ILE C 1 211 ? -1.662 -199.590 17.915 1.00 17.90 ? 269 ILE E CG2 1 ATOM 7824 C CD1 . ILE C 1 211 ? -4.989 -199.558 17.644 1.00 34.97 ? 269 ILE E CD1 1 ATOM 7825 N N . TYR C 1 212 ? 0.126 -197.064 19.546 1.00 14.67 ? 270 TYR E N 1 ATOM 7826 C CA . TYR C 1 212 ? 1.464 -196.550 19.269 1.00 15.01 ? 270 TYR E CA 1 ATOM 7827 C C . TYR C 1 212 ? 2.327 -197.629 18.622 1.00 20.30 ? 270 TYR E C 1 ATOM 7828 O O . TYR C 1 212 ? 2.304 -198.781 19.051 1.00 23.69 ? 270 TYR E O 1 ATOM 7829 C CB . TYR C 1 212 ? 2.111 -196.065 20.570 1.00 15.98 ? 270 TYR E CB 1 ATOM 7830 C CG . TYR C 1 212 ? 3.431 -195.343 20.411 1.00 17.49 ? 270 TYR E CG 1 ATOM 7831 C CD1 . TYR C 1 212 ? 4.606 -196.041 20.166 1.00 17.04 ? 270 TYR E CD1 1 ATOM 7832 C CD2 . TYR C 1 212 ? 3.506 -193.960 20.536 1.00 17.82 ? 270 TYR E CD2 1 ATOM 7833 C CE1 . TYR C 1 212 ? 5.818 -195.382 20.031 1.00 16.60 ? 270 TYR E CE1 1 ATOM 7834 C CE2 . TYR C 1 212 ? 4.712 -193.293 20.405 1.00 14.22 ? 270 TYR E CE2 1 ATOM 7835 C CZ . TYR C 1 212 ? 5.862 -194.006 20.153 1.00 22.38 ? 270 TYR E CZ 1 ATOM 7836 O OH . TYR C 1 212 ? 7.058 -193.335 20.021 1.00 22.26 ? 270 TYR E OH 1 ATOM 7837 N N . GLY C 1 213 ? 3.083 -197.266 17.591 1.00 16.08 ? 271 GLY E N 1 ATOM 7838 C CA . GLY C 1 213 ? 4.001 -198.217 16.989 1.00 17.94 ? 271 GLY E CA 1 ATOM 7839 C C . GLY C 1 213 ? 5.151 -197.575 16.243 1.00 22.79 ? 271 GLY E C 1 ATOM 7840 O O . GLY C 1 213 ? 5.054 -196.436 15.806 1.00 18.79 ? 271 GLY E O 1 ATOM 7841 N N . SER C 1 214 ? 6.254 -198.303 16.103 1.00 17.06 ? 272 SER E N 1 ATOM 7842 C CA . SER C 1 214 ? 7.337 -197.850 15.245 1.00 18.87 ? 272 SER E CA 1 ATOM 7843 C C . SER C 1 214 ? 6.879 -197.957 13.797 1.00 18.07 ? 272 SER E C 1 ATOM 7844 O O . SER C 1 214 ? 5.877 -198.601 13.511 1.00 16.87 ? 272 SER E O 1 ATOM 7845 C CB . SER C 1 214 ? 8.600 -198.678 15.461 1.00 19.00 ? 272 SER E CB 1 ATOM 7846 O OG . SER C 1 214 ? 8.621 -199.802 14.599 1.00 19.95 ? 272 SER E OG 1 ATOM 7847 N N . ALA C 1 215 ? 7.605 -197.331 12.883 1.00 13.92 ? 273 ALA E N 1 ATOM 7848 C CA . ALA C 1 215 ? 7.243 -197.406 11.472 1.00 24.64 ? 273 ALA E CA 1 ATOM 7849 C C . ALA C 1 215 ? 7.308 -198.848 10.972 1.00 27.66 ? 273 ALA E C 1 ATOM 7850 O O . ALA C 1 215 ? 6.583 -199.239 10.054 1.00 23.54 ? 273 ALA E O 1 ATOM 7851 C CB . ALA C 1 215 ? 8.155 -196.523 10.646 1.00 18.53 ? 273 ALA E CB 1 ATOM 7852 N N . TYR C 1 216 ? 8.162 -199.645 11.602 1.00 17.56 ? 274 TYR E N 1 ATOM 7853 C CA . TYR C 1 216 ? 8.510 -200.952 11.069 1.00 25.93 ? 274 TYR E CA 1 ATOM 7854 C C . TYR C 1 216 ? 7.470 -202.044 11.321 1.00 18.76 ? 274 TYR E C 1 ATOM 7855 O O . TYR C 1 216 ? 7.654 -203.171 10.867 1.00 27.77 ? 274 TYR E O 1 ATOM 7856 C CB . TYR C 1 216 ? 9.868 -201.368 11.629 1.00 19.86 ? 274 TYR E CB 1 ATOM 7857 C CG . TYR C 1 216 ? 10.960 -200.461 11.124 1.00 25.68 ? 274 TYR E CG 1 ATOM 7858 C CD1 . TYR C 1 216 ? 11.639 -200.752 9.951 1.00 20.69 ? 274 TYR E CD1 1 ATOM 7859 C CD2 . TYR C 1 216 ? 11.281 -199.288 11.794 1.00 22.71 ? 274 TYR E CD2 1 ATOM 7860 C CE1 . TYR C 1 216 ? 12.624 -199.916 9.469 1.00 20.11 ? 274 TYR E CE1 1 ATOM 7861 C CE2 . TYR C 1 216 ? 12.264 -198.443 11.320 1.00 19.44 ? 274 TYR E CE2 1 ATOM 7862 C CZ . TYR C 1 216 ? 12.930 -198.761 10.153 1.00 24.31 ? 274 TYR E CZ 1 ATOM 7863 O OH . TYR C 1 216 ? 13.913 -197.931 9.666 1.00 28.88 ? 274 TYR E OH 1 ATOM 7864 N N . VAL C 1 217 ? 6.374 -201.727 12.009 1.00 17.12 ? 275 VAL E N 1 ATOM 7865 C CA . VAL C 1 217 ? 5.260 -202.673 12.054 1.00 24.24 ? 275 VAL E CA 1 ATOM 7866 C C . VAL C 1 217 ? 4.552 -202.552 10.702 1.00 27.93 ? 275 VAL E C 1 ATOM 7867 O O . VAL C 1 217 ? 3.751 -203.411 10.333 1.00 23.69 ? 275 VAL E O 1 ATOM 7868 C CB . VAL C 1 217 ? 4.270 -202.450 13.275 1.00 31.33 ? 275 VAL E CB 1 ATOM 7869 C CG1 . VAL C 1 217 ? 4.826 -201.475 14.294 1.00 29.62 ? 275 VAL E CG1 1 ATOM 7870 C CG2 . VAL C 1 217 ? 2.878 -202.010 12.845 1.00 24.28 ? 275 VAL E CG2 1 ATOM 7871 N N . GLY C 1 218 ? 4.895 -201.510 9.941 1.00 28.50 ? 276 GLY E N 1 ATOM 7872 C CA . GLY C 1 218 ? 4.352 -201.327 8.607 1.00 23.02 ? 276 GLY E CA 1 ATOM 7873 C C . GLY C 1 218 ? 5.175 -201.987 7.512 1.00 25.82 ? 276 GLY E C 1 ATOM 7874 O O . GLY C 1 218 ? 4.773 -201.990 6.351 1.00 23.52 ? 276 GLY E O 1 ATOM 7875 N N . GLU C 1 219 ? 6.330 -202.539 7.872 1.00 23.90 ? 277 GLU E N 1 ATOM 7876 C CA . GLU C 1 219 ? 7.199 -203.190 6.894 1.00 33.67 ? 277 GLU E CA 1 ATOM 7877 C C . GLU C 1 219 ? 6.494 -204.397 6.275 1.00 35.92 ? 277 GLU E C 1 ATOM 7878 O O . GLU C 1 219 ? 6.482 -204.564 5.056 1.00 34.90 ? 277 GLU E O 1 ATOM 7879 C CB . GLU C 1 219 ? 8.516 -203.612 7.544 1.00 27.84 ? 277 GLU E CB 1 ATOM 7880 C CG . GLU C 1 219 ? 9.522 -204.180 6.558 1.00 38.64 ? 277 GLU E CG 1 ATOM 7881 C CD . GLU C 1 219 ? 10.911 -204.327 7.149 1.00 44.81 ? 277 GLU E CD 1 ATOM 7882 O OE1 . GLU C 1 219 ? 11.873 -204.490 6.369 1.00 53.81 ? 277 GLU E OE1 1 ATOM 7883 O OE2 . GLU C 1 219 ? 11.043 -204.282 8.391 1.00 57.66 ? 277 GLU E OE2 1 ATOM 7884 N N . ASN C 1 220 ? 5.917 -205.233 7.134 1.00 37.00 ? 278 ASN E N 1 ATOM 7885 C CA . ASN C 1 220 ? 5.012 -206.300 6.718 1.00 32.52 ? 278 ASN E CA 1 ATOM 7886 C C . ASN C 1 220 ? 3.682 -206.105 7.437 1.00 28.06 ? 278 ASN E C 1 ATOM 7887 O O . ASN C 1 220 ? 3.432 -206.730 8.468 1.00 31.52 ? 278 ASN E O 1 ATOM 7888 C CB . ASN C 1 220 ? 5.607 -207.673 7.025 1.00 35.43 ? 278 ASN E CB 1 ATOM 7889 C CG . ASN C 1 220 ? 6.854 -207.954 6.211 1.00 32.06 ? 278 ASN E CG 1 ATOM 7890 O OD1 . ASN C 1 220 ? 7.975 -207.808 6.698 1.00 37.19 ? 278 ASN E OD1 1 ATOM 7891 N ND2 . ASN C 1 220 ? 6.663 -208.340 4.955 1.00 40.03 ? 278 ASN E ND2 1 ATOM 7892 N N . PRO C 1 221 ? 2.822 -205.230 6.889 1.00 31.06 ? 279 PRO E N 1 ATOM 7893 C CA . PRO C 1 221 ? 1.687 -204.658 7.624 1.00 23.40 ? 279 PRO E CA 1 ATOM 7894 C C . PRO C 1 221 ? 0.563 -205.629 7.984 1.00 32.59 ? 279 PRO E C 1 ATOM 7895 O O . PRO C 1 221 ? -0.390 -205.209 8.644 1.00 28.16 ? 279 PRO E O 1 ATOM 7896 C CB . PRO C 1 221 ? 1.165 -203.583 6.663 1.00 28.80 ? 279 PRO E CB 1 ATOM 7897 C CG . PRO C 1 221 ? 1.568 -204.046 5.322 1.00 31.08 ? 279 PRO E CG 1 ATOM 7898 C CD . PRO C 1 221 ? 2.882 -204.731 5.503 1.00 30.18 ? 279 PRO E CD 1 ATOM 7899 N N . ASP C 1 222 ? 0.666 -206.889 7.571 1.00 29.29 ? 280 ASP E N 1 ATOM 7900 C CA . ASP C 1 222 ? -0.347 -207.885 7.913 1.00 27.84 ? 280 ASP E CA 1 ATOM 7901 C C . ASP C 1 222 ? 0.151 -208.835 9.002 1.00 26.90 ? 280 ASP E C 1 ATOM 7902 O O . ASP C 1 222 ? -0.640 -209.537 9.634 1.00 28.75 ? 280 ASP E O 1 ATOM 7903 C CB . ASP C 1 222 ? -0.758 -208.681 6.669 1.00 38.38 ? 280 ASP E CB 1 ATOM 7904 C CG . ASP C 1 222 ? -1.441 -207.818 5.619 1.00 41.95 ? 280 ASP E CG 1 ATOM 7905 O OD1 . ASP C 1 222 ? -2.234 -206.929 5.995 1.00 44.26 ? 280 ASP E OD1 1 ATOM 7906 O OD2 . ASP C 1 222 ? -1.187 -208.029 4.414 1.00 51.38 ? 280 ASP E OD2 1 ATOM 7907 N N . ALA C 1 223 ? 1.462 -208.845 9.221 1.00 28.67 ? 281 ALA E N 1 ATOM 7908 C CA . ALA C 1 223 ? 2.084 -209.766 10.169 1.00 35.82 ? 281 ALA E CA 1 ATOM 7909 C C . ALA C 1 223 ? 1.478 -209.689 11.573 1.00 37.58 ? 281 ALA E C 1 ATOM 7910 O O . ALA C 1 223 ? 1.123 -210.718 12.158 1.00 36.12 ? 281 ALA E O 1 ATOM 7911 C CB . ALA C 1 223 ? 3.576 -209.497 10.237 1.00 28.92 ? 281 ALA E CB 1 ATOM 7912 N N . PHE C 1 224 ? 1.347 -208.471 12.098 1.00 26.03 ? 282 PHE E N 1 ATOM 7913 C CA . PHE C 1 224 ? 0.955 -208.261 13.492 1.00 25.06 ? 282 PHE E CA 1 ATOM 7914 C C . PHE C 1 224 ? -0.323 -209.010 13.857 1.00 29.47 ? 282 PHE E C 1 ATOM 7915 O O . PHE C 1 224 ? -0.544 -209.339 15.022 1.00 23.88 ? 282 PHE E O 1 ATOM 7916 C CB . PHE C 1 224 ? 0.775 -206.763 13.782 1.00 21.54 ? 282 PHE E CB 1 ATOM 7917 C CG . PHE C 1 224 ? -0.559 -206.213 13.355 1.00 21.35 ? 282 PHE E CG 1 ATOM 7918 C CD1 . PHE C 1 224 ? -1.657 -206.289 14.197 1.00 23.58 ? 282 PHE E CD1 1 ATOM 7919 C CD2 . PHE C 1 224 ? -0.713 -205.608 12.118 1.00 28.52 ? 282 PHE E CD2 1 ATOM 7920 C CE1 . PHE C 1 224 ? -2.884 -205.787 13.811 1.00 30.64 ? 282 PHE E CE1 1 ATOM 7921 C CE2 . PHE C 1 224 ? -1.938 -205.100 11.728 1.00 24.99 ? 282 PHE E CE2 1 ATOM 7922 C CZ . PHE C 1 224 ? -3.024 -205.189 12.575 1.00 27.06 ? 282 PHE E CZ 1 ATOM 7923 N N . ILE C 1 225 ? -1.162 -209.268 12.859 1.00 26.89 ? 283 ILE E N 1 ATOM 7924 C CA . ILE C 1 225 ? -2.416 -209.979 13.077 1.00 33.51 ? 283 ILE E CA 1 ATOM 7925 C C . ILE C 1 225 ? -2.182 -211.330 13.741 1.00 35.21 ? 283 ILE E C 1 ATOM 7926 O O . ILE C 1 225 ? -2.963 -211.747 14.598 1.00 41.65 ? 283 ILE E O 1 ATOM 7927 C CB . ILE C 1 225 ? -3.171 -210.192 11.750 1.00 35.66 ? 283 ILE E CB 1 ATOM 7928 C CG1 . ILE C 1 225 ? -3.654 -208.851 11.197 1.00 45.55 ? 283 ILE E CG1 1 ATOM 7929 C CG2 . ILE C 1 225 ? -4.371 -211.120 11.944 1.00 36.18 ? 283 ILE E CG2 1 ATOM 7930 C CD1 . ILE C 1 225 ? -4.031 -208.896 9.732 1.00 41.62 ? 283 ILE E CD1 1 ATOM 7931 N N . SER C 1 226 ? -1.100 -212.002 13.353 1.00 29.18 ? 284 SER E N 1 ATOM 7932 C CA . SER C 1 226 ? -0.842 -213.362 13.817 1.00 42.54 ? 284 SER E CA 1 ATOM 7933 C C . SER C 1 226 ? 0.370 -213.446 14.741 1.00 37.45 ? 284 SER E C 1 ATOM 7934 O O . SER C 1 226 ? 0.470 -214.360 15.558 1.00 43.33 ? 284 SER E O 1 ATOM 7935 C CB . SER C 1 226 ? -0.639 -214.289 12.617 1.00 38.46 ? 284 SER E CB 1 ATOM 7936 O OG . SER C 1 226 ? 0.445 -213.850 11.817 1.00 41.86 ? 284 SER E OG 1 ATOM 7937 N N . LYS C 1 227 ? 1.279 -212.484 14.612 1.00 31.24 ? 285 LYS E N 1 ATOM 7938 C CA . LYS C 1 227 ? 2.565 -212.540 15.299 1.00 27.47 ? 285 LYS E CA 1 ATOM 7939 C C . LYS C 1 227 ? 2.652 -211.645 16.536 1.00 34.31 ? 285 LYS E C 1 ATOM 7940 O O . LYS C 1 227 ? 3.721 -211.532 17.137 1.00 36.12 ? 285 LYS E O 1 ATOM 7941 C CB . LYS C 1 227 ? 3.681 -212.164 14.321 1.00 35.87 ? 285 LYS E CB 1 ATOM 7942 C CG . LYS C 1 227 ? 3.879 -213.171 13.199 1.00 40.77 ? 285 LYS E CG 1 ATOM 7943 C CD . LYS C 1 227 ? 4.821 -212.636 12.129 1.00 54.12 ? 285 LYS E CD 1 ATOM 7944 C CE . LYS C 1 227 ? 5.959 -213.603 11.835 1.00 64.56 ? 285 LYS E CE 1 ATOM 7945 N NZ . LYS C 1 227 ? 5.476 -214.966 11.478 1.00 54.02 ? 285 LYS E NZ 1 ATOM 7946 N N . CYS C 1 228 ? 1.542 -211.021 16.924 1.00 27.36 ? 286 CYS E N 1 ATOM 7947 C CA . CYS C 1 228 ? 1.544 -210.105 18.067 1.00 30.73 ? 286 CYS E CA 1 ATOM 7948 C C . CYS C 1 228 ? 0.370 -210.363 19.010 1.00 30.67 ? 286 CYS E C 1 ATOM 7949 O O . CYS C 1 228 ? -0.720 -210.715 18.562 1.00 30.68 ? 286 CYS E O 1 ATOM 7950 C CB . CYS C 1 228 ? 1.514 -208.652 17.586 1.00 25.06 ? 286 CYS E CB 1 ATOM 7951 S SG . CYS C 1 228 ? 2.976 -208.163 16.637 1.00 31.80 ? 286 CYS E SG 1 ATOM 7952 N N . PRO C 1 229 ? 0.587 -210.175 20.325 1.00 27.86 ? 287 PRO E N 1 ATOM 7953 C CA . PRO C 1 229 ? -0.446 -210.428 21.333 1.00 23.41 ? 287 PRO E CA 1 ATOM 7954 C C . PRO C 1 229 ? -1.385 -209.235 21.489 1.00 32.56 ? 287 PRO E C 1 ATOM 7955 O O . PRO C 1 229 ? -1.385 -208.567 22.525 1.00 25.31 ? 287 PRO E O 1 ATOM 7956 C CB . PRO C 1 229 ? 0.375 -210.663 22.599 1.00 30.48 ? 287 PRO E CB 1 ATOM 7957 C CG . PRO C 1 229 ? 1.532 -209.732 22.436 1.00 26.89 ? 287 PRO E CG 1 ATOM 7958 C CD . PRO C 1 229 ? 1.819 -209.656 20.949 1.00 21.85 ? 287 PRO E CD 1 ATOM 7959 N N . ASN C 1 230 ? -2.186 -208.984 20.460 1.00 28.09 ? 288 ASN E N 1 ATOM 7960 C CA . ASN C 1 230 ? -2.966 -207.757 20.369 1.00 27.58 ? 288 ASN E CA 1 ATOM 7961 C C . ASN C 1 230 ? -4.044 -207.635 21.440 1.00 27.21 ? 288 ASN E C 1 ATOM 7962 O O . ASN C 1 230 ? -4.286 -206.547 21.962 1.00 32.69 ? 288 ASN E O 1 ATOM 7963 C CB . ASN C 1 230 ? -3.600 -207.659 18.980 1.00 21.34 ? 288 ASN E CB 1 ATOM 7964 C CG . ASN C 1 230 ? -2.564 -207.615 17.876 1.00 23.23 ? 288 ASN E CG 1 ATOM 7965 O OD1 . ASN C 1 230 ? -1.614 -206.831 17.931 1.00 25.39 ? 288 ASN E OD1 1 ATOM 7966 N ND2 . ASN C 1 230 ? -2.728 -208.472 16.876 1.00 31.36 ? 288 ASN E ND2 1 ATOM 7967 N N . GLN C 1 231 ? -4.686 -208.753 21.765 1.00 23.07 ? 289 GLN E N 1 ATOM 7968 C CA . GLN C 1 231 ? -5.779 -208.757 22.728 1.00 21.20 ? 289 GLN E CA 1 ATOM 7969 C C . GLN C 1 231 ? -5.396 -209.436 24.038 1.00 23.54 ? 289 GLN E C 1 ATOM 7970 O O . GLN C 1 231 ? -4.489 -210.265 24.082 1.00 24.36 ? 289 GLN E O 1 ATOM 7971 C CB . GLN C 1 231 ? -7.004 -209.451 22.127 1.00 30.38 ? 289 GLN E CB 1 ATOM 7972 C CG . GLN C 1 231 ? -7.982 -208.498 21.453 1.00 40.69 ? 289 GLN E CG 1 ATOM 7973 C CD . GLN C 1 231 ? -7.325 -207.625 20.399 1.00 53.32 ? 289 GLN E CD 1 ATOM 7974 O OE1 . GLN C 1 231 ? -7.352 -206.396 20.488 1.00 46.37 ? 289 GLN E OE1 1 ATOM 7975 N NE2 . GLN C 1 231 ? -6.739 -208.257 19.388 1.00 37.30 ? 289 GLN E NE2 1 ATOM 7976 N N . ALA C 1 232 ? -6.094 -209.065 25.105 1.00 22.50 ? 290 ALA E N 1 ATOM 7977 C CA . ALA C 1 232 ? -5.974 -209.756 26.381 1.00 24.00 ? 290 ALA E CA 1 ATOM 7978 C C . ALA C 1 232 ? -6.579 -211.151 26.263 1.00 32.61 ? 290 ALA E C 1 ATOM 7979 O O . ALA C 1 232 ? -7.459 -211.378 25.434 1.00 28.45 ? 290 ALA E O 1 ATOM 7980 C CB . ALA C 1 232 ? -6.660 -208.971 27.475 1.00 19.88 ? 290 ALA E CB 1 ATOM 7981 N N . LEU C 1 233 ? -6.111 -212.077 27.097 1.00 32.42 ? 291 LEU E N 1 ATOM 7982 C CA . LEU C 1 233 ? -6.566 -213.465 27.049 1.00 23.97 ? 291 LEU E CA 1 ATOM 7983 C C . LEU C 1 233 ? -7.424 -213.815 28.260 1.00 28.46 ? 291 LEU E C 1 ATOM 7984 O O . LEU C 1 233 ? -6.919 -213.961 29.374 1.00 27.82 ? 291 LEU E O 1 ATOM 7985 C CB . LEU C 1 233 ? -5.363 -214.405 26.959 1.00 28.36 ? 291 LEU E CB 1 ATOM 7986 C CG . LEU C 1 233 ? -5.648 -215.903 26.832 1.00 40.81 ? 291 LEU E CG 1 ATOM 7987 C CD1 . LEU C 1 233 ? -6.594 -216.202 25.677 1.00 40.23 ? 291 LEU E CD1 1 ATOM 7988 C CD2 . LEU C 1 233 ? -4.342 -216.659 26.653 1.00 30.99 ? 291 LEU E CD2 1 ATOM 7989 N N . ARG C 1 234 ? -8.726 -213.952 28.031 1.00 20.75 ? 292 ARG E N 1 ATOM 7990 C CA . ARG C 1 234 ? -9.675 -214.222 29.105 1.00 34.36 ? 292 ARG E CA 1 ATOM 7991 C C . ARG C 1 234 ? -9.667 -215.689 29.515 1.00 35.80 ? 292 ARG E C 1 ATOM 7992 O O . ARG C 1 234 ? -9.594 -216.578 28.669 1.00 33.35 ? 292 ARG E O 1 ATOM 7993 C CB . ARG C 1 234 ? -11.092 -213.829 28.681 1.00 31.65 ? 292 ARG E CB 1 ATOM 7994 C CG . ARG C 1 234 ? -12.110 -213.888 29.810 1.00 49.91 ? 292 ARG E CG 1 ATOM 7995 C CD . ARG C 1 234 ? -13.526 -213.666 29.303 1.00 55.72 ? 292 ARG E CD 1 ATOM 7996 N NE . ARG C 1 234 ? -14.505 -213.716 30.388 1.00 101.37 ? 292 ARG E NE 1 ATOM 7997 C CZ . ARG C 1 234 ? -14.862 -212.674 31.135 1.00 109.01 ? 292 ARG E CZ 1 ATOM 7998 N NH1 . ARG C 1 234 ? -14.327 -211.477 30.927 1.00 102.18 ? 292 ARG E NH1 1 ATOM 7999 N NH2 . ARG C 1 234 ? -15.762 -212.828 32.097 1.00 87.86 ? 292 ARG E NH2 1 ATOM 8000 N N . GLY C 1 235 ? -9.748 -215.931 30.820 1.00 33.37 ? 293 GLY E N 1 ATOM 8001 C CA . GLY C 1 235 ? -9.951 -217.272 31.339 1.00 34.04 ? 293 GLY E CA 1 ATOM 8002 C C . GLY C 1 235 ? -8.702 -218.126 31.448 1.00 39.15 ? 293 GLY E C 1 ATOM 8003 O O . GLY C 1 235 ? -8.799 -219.327 31.691 1.00 35.24 ? 293 GLY E O 1 ATOM 8004 N N . TYR C 1 236 ? -7.532 -217.518 31.273 1.00 35.24 ? 294 TYR E N 1 ATOM 8005 C CA . TYR C 1 236 ? -6.277 -218.258 31.352 1.00 21.19 ? 294 TYR E CA 1 ATOM 8006 C C . TYR C 1 236 ? -5.173 -217.461 32.034 1.00 35.09 ? 294 TYR E C 1 ATOM 8007 O O . TYR C 1 236 ? -5.101 -216.236 31.914 1.00 32.76 ? 294 TYR E O 1 ATOM 8008 C CB . TYR C 1 236 ? -5.810 -218.671 29.956 1.00 31.45 ? 294 TYR E CB 1 ATOM 8009 C CG . TYR C 1 236 ? -6.738 -219.630 29.250 1.00 47.64 ? 294 TYR E CG 1 ATOM 8010 C CD1 . TYR C 1 236 ? -7.797 -219.165 28.483 1.00 43.87 ? 294 TYR E CD1 1 ATOM 8011 C CD2 . TYR C 1 236 ? -6.550 -221.002 29.344 1.00 42.08 ? 294 TYR E CD2 1 ATOM 8012 C CE1 . TYR C 1 236 ? -8.647 -220.037 27.833 1.00 44.50 ? 294 TYR E CE1 1 ATOM 8013 C CE2 . TYR C 1 236 ? -7.395 -221.884 28.698 1.00 51.54 ? 294 TYR E CE2 1 ATOM 8014 C CZ . TYR C 1 236 ? -8.442 -221.396 27.943 1.00 50.46 ? 294 TYR E CZ 1 ATOM 8015 O OH . TYR C 1 236 ? -9.289 -222.265 27.296 1.00 45.26 ? 294 TYR E OH 1 ATOM 8016 N N . ARG C 1 237 ? -4.323 -218.184 32.755 1.00 31.64 ? 295 ARG E N 1 ATOM 8017 C CA . ARG C 1 237 ? -3.095 -217.643 33.316 1.00 26.93 ? 295 ARG E CA 1 ATOM 8018 C C . ARG C 1 237 ? -1.914 -218.068 32.460 1.00 28.96 ? 295 ARG E C 1 ATOM 8019 O O . ARG C 1 237 ? -1.802 -219.244 32.098 1.00 27.92 ? 295 ARG E O 1 ATOM 8020 C CB . ARG C 1 237 ? -2.871 -218.135 34.744 1.00 23.30 ? 295 ARG E CB 1 ATOM 8021 C CG . ARG C 1 237 ? -3.997 -217.883 35.722 1.00 28.48 ? 295 ARG E CG 1 ATOM 8022 C CD . ARG C 1 237 ? -3.601 -218.427 37.089 1.00 25.06 ? 295 ARG E CD 1 ATOM 8023 N NE . ARG C 1 237 ? -4.601 -218.173 38.120 1.00 23.92 ? 295 ARG E NE 1 ATOM 8024 C CZ . ARG C 1 237 ? -4.363 -218.252 39.426 1.00 24.55 ? 295 ARG E CZ 1 ATOM 8025 N NH1 . ARG C 1 237 ? -5.334 -218.006 40.292 1.00 26.66 ? 295 ARG E NH1 1 ATOM 8026 N NH2 . ARG C 1 237 ? -3.154 -218.572 39.872 1.00 26.49 ? 295 ARG E NH2 1 ATOM 8027 N N . PHE C 1 238 ? -1.038 -217.118 32.143 1.00 22.61 ? 296 PHE E N 1 ATOM 8028 C CA . PHE C 1 238 ? 0.230 -217.427 31.498 1.00 21.47 ? 296 PHE E CA 1 ATOM 8029 C C . PHE C 1 238 ? 1.018 -218.408 32.355 1.00 26.13 ? 296 PHE E C 1 ATOM 8030 O O . PHE C 1 238 ? 1.024 -218.299 33.582 1.00 24.02 ? 296 PHE E O 1 ATOM 8031 C CB . PHE C 1 238 ? 1.062 -216.157 31.278 1.00 22.67 ? 296 PHE E CB 1 ATOM 8032 C CG . PHE C 1 238 ? 0.600 -215.298 30.129 1.00 25.88 ? 296 PHE E CG 1 ATOM 8033 C CD1 . PHE C 1 238 ? 0.019 -215.855 29.002 1.00 26.52 ? 296 PHE E CD1 1 ATOM 8034 C CD2 . PHE C 1 238 ? 0.763 -213.923 30.180 1.00 24.53 ? 296 PHE E CD2 1 ATOM 8035 C CE1 . PHE C 1 238 ? -0.396 -215.057 27.954 1.00 33.00 ? 296 PHE E CE1 1 ATOM 8036 C CE2 . PHE C 1 238 ? 0.350 -213.120 29.135 1.00 24.17 ? 296 PHE E CE2 1 ATOM 8037 C CZ . PHE C 1 238 ? -0.230 -213.686 28.021 1.00 22.39 ? 296 PHE E CZ 1 ATOM 8038 N N . GLY C 1 239 ? 1.681 -219.363 31.710 1.00 31.71 ? 297 GLY E N 1 ATOM 8039 C CA . GLY C 1 239 ? 2.507 -220.311 32.430 1.00 27.25 ? 297 GLY E CA 1 ATOM 8040 C C . GLY C 1 239 ? 3.682 -220.856 31.646 1.00 31.26 ? 297 GLY E C 1 ATOM 8041 O O . GLY C 1 239 ? 3.727 -220.774 30.414 1.00 37.51 ? 297 GLY E O 1 ATOM 8042 N N . VAL C 1 240 ? 4.634 -221.421 32.384 1.00 26.56 ? 298 VAL E N 1 ATOM 8043 C CA . VAL C 1 240 ? 5.805 -222.060 31.796 1.00 32.76 ? 298 VAL E CA 1 ATOM 8044 C C . VAL C 1 240 ? 5.713 -223.572 31.984 1.00 41.12 ? 298 VAL E C 1 ATOM 8045 O O . VAL C 1 240 ? 5.256 -224.054 33.023 1.00 36.38 ? 298 VAL E O 1 ATOM 8046 C CB . VAL C 1 240 ? 7.117 -221.539 32.414 1.00 29.25 ? 298 VAL E CB 1 ATOM 8047 C CG1 . VAL C 1 240 ? 7.321 -220.075 32.057 1.00 39.72 ? 298 VAL E CG1 1 ATOM 8048 C CG2 . VAL C 1 240 ? 7.124 -221.732 33.927 1.00 43.80 ? 298 VAL E CG2 1 ATOM 8049 N N . TRP C 1 241 ? 6.138 -224.316 30.969 1.00 44.55 ? 299 TRP E N 1 ATOM 8050 C CA . TRP C 1 241 ? 6.064 -225.770 31.001 1.00 41.02 ? 299 TRP E CA 1 ATOM 8051 C C . TRP C 1 241 ? 7.308 -226.365 31.645 1.00 33.93 ? 299 TRP E C 1 ATOM 8052 O O . TRP C 1 241 ? 8.403 -226.297 31.084 1.00 38.00 ? 299 TRP E O 1 ATOM 8053 C CB . TRP C 1 241 ? 5.887 -226.324 29.589 1.00 46.40 ? 299 TRP E CB 1 ATOM 8054 C CG . TRP C 1 241 ? 5.637 -227.797 29.555 1.00 45.03 ? 299 TRP E CG 1 ATOM 8055 C CD1 . TRP C 1 241 ? 6.553 -228.777 29.316 1.00 44.86 ? 299 TRP E CD1 1 ATOM 8056 C CD2 . TRP C 1 241 ? 4.385 -228.459 29.769 1.00 39.38 ? 299 TRP E CD2 1 ATOM 8057 N NE1 . TRP C 1 241 ? 5.949 -230.010 29.365 1.00 44.30 ? 299 TRP E NE1 1 ATOM 8058 C CE2 . TRP C 1 241 ? 4.618 -229.842 29.641 1.00 44.44 ? 299 TRP E CE2 1 ATOM 8059 C CE3 . TRP C 1 241 ? 3.089 -228.017 30.055 1.00 41.44 ? 299 TRP E CE3 1 ATOM 8060 C CZ2 . TRP C 1 241 ? 3.606 -230.786 29.790 1.00 40.67 ? 299 TRP E CZ2 1 ATOM 8061 C CZ3 . TRP C 1 241 ? 2.085 -228.957 30.202 1.00 42.85 ? 299 TRP E CZ3 1 ATOM 8062 C CH2 . TRP C 1 241 ? 2.350 -230.325 30.069 1.00 45.21 ? 299 TRP E CH2 1 ATOM 8063 N N . LYS C 1 242 ? 7.129 -226.948 32.825 1.00 37.75 ? 300 LYS E N 1 ATOM 8064 C CA . LYS C 1 242 ? 8.235 -227.549 33.559 1.00 51.40 ? 300 LYS E CA 1 ATOM 8065 C C . LYS C 1 242 ? 7.824 -228.870 34.202 1.00 41.12 ? 300 LYS E C 1 ATOM 8066 O O . LYS C 1 242 ? 6.674 -229.043 34.619 1.00 36.64 ? 300 LYS E O 1 ATOM 8067 C CB . LYS C 1 242 ? 8.762 -226.574 34.616 1.00 46.43 ? 300 LYS E CB 1 ATOM 8068 C CG . LYS C 1 242 ? 9.961 -225.762 34.131 1.00 63.78 ? 300 LYS E CG 1 ATOM 8069 C CD . LYS C 1 242 ? 9.976 -224.327 34.655 1.00 64.23 ? 300 LYS E CD 1 ATOM 8070 C CE . LYS C 1 242 ? 10.776 -224.190 35.942 1.00 74.33 ? 300 LYS E CE 1 ATOM 8071 N NZ . LYS C 1 242 ? 11.045 -222.760 36.267 1.00 70.19 ? 300 LYS E NZ 1 ATOM 8072 N N . LYS C 1 243 ? 8.785 -229.792 34.250 1.00 58.22 ? 301 LYS E N 1 ATOM 8073 C CA . LYS C 1 243 ? 8.602 -231.136 34.799 1.00 45.10 ? 301 LYS E CA 1 ATOM 8074 C C . LYS C 1 243 ? 7.243 -231.734 34.441 1.00 40.62 ? 301 LYS E C 1 ATOM 8075 O O . LYS C 1 243 ? 6.517 -232.234 35.299 1.00 40.78 ? 301 LYS E O 1 ATOM 8076 C CB . LYS C 1 243 ? 8.803 -231.112 36.317 1.00 49.00 ? 301 LYS E CB 1 ATOM 8077 C CG . LYS C 1 243 ? 10.272 -231.083 36.722 1.00 54.30 ? 301 LYS E CG 1 ATOM 8078 C CD . LYS C 1 243 ? 10.521 -230.183 37.917 1.00 82.23 ? 301 LYS E CD 1 ATOM 8079 C CE . LYS C 1 243 ? 10.455 -228.713 37.527 1.00 93.72 ? 301 LYS E CE 1 ATOM 8080 N NZ . LYS C 1 243 ? 10.619 -227.811 38.698 1.00 74.47 ? 301 LYS E NZ 1 ATOM 8081 N N . GLY C 1 244 ? 6.908 -231.660 33.158 1.00 39.80 ? 302 GLY E N 1 ATOM 8082 C CA . GLY C 1 244 ? 5.731 -232.324 32.635 1.00 35.07 ? 302 GLY E CA 1 ATOM 8083 C C . GLY C 1 244 ? 4.413 -231.638 32.929 1.00 44.26 ? 302 GLY E C 1 ATOM 8084 O O . GLY C 1 244 ? 3.354 -232.231 32.715 1.00 41.28 ? 302 GLY E O 1 ATOM 8085 N N . ARG C 1 245 ? 4.453 -230.402 33.420 1.00 37.90 ? 303 ARG E N 1 ATOM 8086 C CA . ARG C 1 245 ? 3.210 -229.670 33.634 1.00 46.22 ? 303 ARG E CA 1 ATOM 8087 C C . ARG C 1 245 ? 3.383 -228.161 33.506 1.00 33.08 ? 303 ARG E C 1 ATOM 8088 O O . ARG C 1 245 ? 4.501 -227.642 33.457 1.00 35.18 ? 303 ARG E O 1 ATOM 8089 C CB . ARG C 1 245 ? 2.622 -230.014 35.006 1.00 33.13 ? 303 ARG E CB 1 ATOM 8090 C CG . ARG C 1 245 ? 3.558 -229.759 36.161 1.00 42.26 ? 303 ARG E CG 1 ATOM 8091 C CD . ARG C 1 245 ? 2.901 -230.105 37.483 1.00 40.91 ? 303 ARG E CD 1 ATOM 8092 N NE . ARG C 1 245 ? 3.671 -229.585 38.612 1.00 38.77 ? 303 ARG E NE 1 ATOM 8093 C CZ . ARG C 1 245 ? 3.334 -228.529 39.350 1.00 41.99 ? 303 ARG E CZ 1 ATOM 8094 N NH1 . ARG C 1 245 ? 2.216 -227.854 39.111 1.00 40.00 ? 303 ARG E NH1 1 ATOM 8095 N NH2 . ARG C 1 245 ? 4.122 -228.150 40.345 1.00 49.99 ? 303 ARG E NH2 1 ATOM 8096 N N . CYS C 1 246 ? 2.250 -227.470 33.446 1.00 36.81 ? 304 CYS E N 1 ATOM 8097 C CA . CYS C 1 246 ? 2.232 -226.029 33.255 1.00 40.25 ? 304 CYS E CA 1 ATOM 8098 C C . CYS C 1 246 ? 2.190 -225.297 34.591 1.00 28.21 ? 304 CYS E C 1 ATOM 8099 O O . CYS C 1 246 ? 1.194 -225.366 35.313 1.00 32.36 ? 304 CYS E O 1 ATOM 8100 C CB . CYS C 1 246 ? 1.029 -225.624 32.399 1.00 45.18 ? 304 CYS E CB 1 ATOM 8101 S SG . CYS C 1 246 ? 1.126 -223.937 31.756 1.00 59.13 ? 304 CYS E SG 1 ATOM 8102 N N . LEU C 1 247 ? 3.277 -224.601 34.915 1.00 30.52 ? 305 LEU E N 1 ATOM 8103 C CA . LEU C 1 247 ? 3.328 -223.756 36.105 1.00 32.77 ? 305 LEU E CA 1 ATOM 8104 C C . LEU C 1 247 ? 2.950 -222.325 35.744 1.00 28.80 ? 305 LEU E C 1 ATOM 8105 O O . LEU C 1 247 ? 3.669 -221.664 34.991 1.00 25.51 ? 305 LEU E O 1 ATOM 8106 C CB . LEU C 1 247 ? 4.723 -223.769 36.735 1.00 34.50 ? 305 LEU E CB 1 ATOM 8107 C CG . LEU C 1 247 ? 5.407 -225.117 36.967 1.00 41.88 ? 305 LEU E CG 1 ATOM 8108 C CD1 . LEU C 1 247 ? 6.610 -224.928 37.877 1.00 44.44 ? 305 LEU E CD1 1 ATOM 8109 C CD2 . LEU C 1 247 ? 4.449 -226.139 37.549 1.00 48.66 ? 305 LEU E CD2 1 ATOM 8110 N N . ASP C 1 248 ? 1.830 -221.844 36.274 1.00 31.33 ? 306 ASP E N 1 ATOM 8111 C CA . ASP C 1 248 ? 1.469 -220.447 36.084 1.00 31.99 ? 306 ASP E CA 1 ATOM 8112 C C . ASP C 1 248 ? 2.416 -219.607 36.933 1.00 35.37 ? 306 ASP E C 1 ATOM 8113 O O . ASP C 1 248 ? 3.040 -220.122 37.862 1.00 32.72 ? 306 ASP E O 1 ATOM 8114 C CB . ASP C 1 248 ? 0.008 -220.188 36.454 1.00 32.32 ? 306 ASP E CB 1 ATOM 8115 C CG . ASP C 1 248 ? -0.230 -220.209 37.946 1.00 43.37 ? 306 ASP E CG 1 ATOM 8116 O OD1 . ASP C 1 248 ? -0.054 -219.152 38.588 1.00 45.31 ? 306 ASP E OD1 1 ATOM 8117 O OD2 . ASP C 1 248 ? -0.602 -221.276 38.476 1.00 56.46 ? 306 ASP E OD2 1 ATOM 8118 N N . TYR C 1 249 ? 2.523 -218.322 36.612 1.00 26.45 ? 307 TYR E N 1 ATOM 8119 C CA . TYR C 1 249 ? 3.545 -217.456 37.197 1.00 29.97 ? 307 TYR E CA 1 ATOM 8120 C C . TYR C 1 249 ? 3.571 -217.435 38.728 1.00 22.55 ? 307 TYR E C 1 ATOM 8121 O O . TYR C 1 249 ? 4.624 -217.209 39.323 1.00 23.26 ? 307 TYR E O 1 ATOM 8122 C CB . TYR C 1 249 ? 3.363 -216.022 36.692 1.00 23.52 ? 307 TYR E CB 1 ATOM 8123 C CG . TYR C 1 249 ? 3.683 -215.803 35.224 1.00 19.54 ? 307 TYR E CG 1 ATOM 8124 C CD1 . TYR C 1 249 ? 4.611 -216.595 34.556 1.00 25.30 ? 307 TYR E CD1 1 ATOM 8125 C CD2 . TYR C 1 249 ? 3.063 -214.786 34.512 1.00 25.97 ? 307 TYR E CD2 1 ATOM 8126 C CE1 . TYR C 1 249 ? 4.902 -216.382 33.217 1.00 26.22 ? 307 TYR E CE1 1 ATOM 8127 C CE2 . TYR C 1 249 ? 3.347 -214.566 33.179 1.00 17.08 ? 307 TYR E CE2 1 ATOM 8128 C CZ . TYR C 1 249 ? 4.265 -215.362 32.535 1.00 24.28 ? 307 TYR E CZ 1 ATOM 8129 O OH . TYR C 1 249 ? 4.538 -215.128 31.205 1.00 23.48 ? 307 TYR E OH 1 ATOM 8130 N N . THR C 1 250 ? 2.429 -217.659 39.371 1.00 19.57 ? 308 THR E N 1 ATOM 8131 C CA . THR C 1 250 ? 2.382 -217.605 40.830 1.00 29.67 ? 308 THR E CA 1 ATOM 8132 C C . THR C 1 250 ? 3.192 -218.733 41.466 1.00 28.70 ? 308 THR E C 1 ATOM 8133 O O . THR C 1 250 ? 3.560 -218.650 42.635 1.00 37.92 ? 308 THR E O 1 ATOM 8134 C CB . THR C 1 250 ? 0.940 -217.679 41.367 1.00 25.06 ? 308 THR E CB 1 ATOM 8135 O OG1 . THR C 1 250 ? 0.355 -218.937 41.013 1.00 40.56 ? 308 THR E OG1 1 ATOM 8136 C CG2 . THR C 1 250 ? 0.094 -216.542 40.809 1.00 28.12 ? 308 THR E CG2 1 ATOM 8137 N N . GLU C 1 251 ? 3.471 -219.783 40.698 1.00 28.62 ? 309 GLU E N 1 ATOM 8138 C CA . GLU C 1 251 ? 4.273 -220.896 41.198 1.00 33.01 ? 309 GLU E CA 1 ATOM 8139 C C . GLU C 1 251 ? 5.771 -220.614 41.096 1.00 42.49 ? 309 GLU E C 1 ATOM 8140 O O . GLU C 1 251 ? 6.583 -221.352 41.654 1.00 40.97 ? 309 GLU E O 1 ATOM 8141 C CB . GLU C 1 251 ? 3.943 -222.183 40.437 1.00 33.03 ? 309 GLU E CB 1 ATOM 8142 C CG . GLU C 1 251 ? 2.558 -222.743 40.731 1.00 39.08 ? 309 GLU E CG 1 ATOM 8143 C CD . GLU C 1 251 ? 2.461 -224.236 40.462 1.00 79.79 ? 309 GLU E CD 1 ATOM 8144 O OE1 . GLU C 1 251 ? 3.334 -224.990 40.944 1.00 72.77 ? 309 GLU E OE1 1 ATOM 8145 O OE2 . GLU C 1 251 ? 1.511 -224.657 39.768 1.00 68.80 ? 309 GLU E OE2 1 ATOM 8146 N N . LEU C 1 252 ? 6.132 -219.547 40.388 1.00 34.58 ? 310 LEU E N 1 ATOM 8147 C CA . LEU C 1 252 ? 7.537 -219.214 40.164 1.00 31.26 ? 310 LEU E CA 1 ATOM 8148 C C . LEU C 1 252 ? 8.043 -218.210 41.197 1.00 37.78 ? 310 LEU E C 1 ATOM 8149 O O . LEU C 1 252 ? 7.318 -217.305 41.611 1.00 39.90 ? 310 LEU E O 1 ATOM 8150 C CB . LEU C 1 252 ? 7.734 -218.661 38.752 1.00 38.89 ? 310 LEU E CB 1 ATOM 8151 C CG . LEU C 1 252 ? 7.094 -219.477 37.626 1.00 36.73 ? 310 LEU E CG 1 ATOM 8152 C CD1 . LEU C 1 252 ? 7.387 -218.840 36.275 1.00 30.95 ? 310 LEU E CD1 1 ATOM 8153 C CD2 . LEU C 1 252 ? 7.567 -220.925 37.648 1.00 39.13 ? 310 LEU E CD2 1 ATOM 8154 N N . THR C 1 253 ? 9.298 -218.380 41.601 1.00 43.18 ? 311 THR E N 1 ATOM 8155 C CA . THR C 1 253 ? 9.902 -217.571 42.656 1.00 45.74 ? 311 THR E CA 1 ATOM 8156 C C . THR C 1 253 ? 10.078 -216.106 42.257 1.00 34.00 ? 311 THR E C 1 ATOM 8157 O O . THR C 1 253 ? 9.782 -215.205 43.041 1.00 41.07 ? 311 THR E O 1 ATOM 8158 C CB . THR C 1 253 ? 11.278 -218.157 43.061 1.00 52.15 ? 311 THR E CB 1 ATOM 8159 O OG1 . THR C 1 253 ? 11.079 -219.321 43.870 1.00 66.59 ? 311 THR E OG1 1 ATOM 8160 C CG2 . THR C 1 253 ? 12.122 -217.146 43.845 1.00 55.87 ? 311 THR E CG2 1 ATOM 8161 N N . ASP C 1 254 ? 10.563 -215.876 41.040 1.00 36.58 ? 312 ASP E N 1 ATOM 8162 C CA . ASP C 1 254 ? 10.911 -214.529 40.594 1.00 42.37 ? 312 ASP E CA 1 ATOM 8163 C C . ASP C 1 254 ? 9.695 -213.690 40.208 1.00 37.21 ? 312 ASP E C 1 ATOM 8164 O O . ASP C 1 254 ? 9.820 -212.494 39.950 1.00 31.56 ? 312 ASP E O 1 ATOM 8165 C CB . ASP C 1 254 ? 11.875 -214.604 39.408 1.00 43.09 ? 312 ASP E CB 1 ATOM 8166 C CG . ASP C 1 254 ? 13.206 -215.234 39.775 1.00 66.02 ? 312 ASP E CG 1 ATOM 8167 O OD1 . ASP C 1 254 ? 13.563 -215.224 40.973 1.00 59.48 ? 312 ASP E OD1 1 ATOM 8168 O OD2 . ASP C 1 254 ? 13.899 -215.736 38.864 1.00 61.00 ? 312 ASP E OD2 1 ATOM 8169 N N . THR C 1 255 ? 8.524 -214.315 40.164 1.00 29.20 ? 313 THR E N 1 ATOM 8170 C CA . THR C 1 255 ? 7.297 -213.610 39.818 1.00 22.70 ? 313 THR E CA 1 ATOM 8171 C C . THR C 1 255 ? 6.984 -212.520 40.840 1.00 32.23 ? 313 THR E C 1 ATOM 8172 O O . THR C 1 255 ? 7.097 -212.740 42.046 1.00 30.84 ? 313 THR E O 1 ATOM 8173 C CB . THR C 1 255 ? 6.109 -214.584 39.730 1.00 20.80 ? 313 THR E CB 1 ATOM 8174 O OG1 . THR C 1 255 ? 6.327 -215.498 38.650 1.00 24.16 ? 313 THR E OG1 1 ATOM 8175 C CG2 . THR C 1 255 ? 4.800 -213.842 39.496 1.00 23.28 ? 313 THR E CG2 1 ATOM 8176 N N . VAL C 1 256 ? 6.589 -211.349 40.348 1.00 24.63 ? 314 VAL E N 1 ATOM 8177 C CA . VAL C 1 256 ? 6.185 -210.246 41.215 1.00 19.88 ? 314 VAL E CA 1 ATOM 8178 C C . VAL C 1 256 ? 4.668 -210.228 41.361 1.00 17.79 ? 314 VAL E C 1 ATOM 8179 O O . VAL C 1 256 ? 3.941 -210.239 40.369 1.00 22.30 ? 314 VAL E O 1 ATOM 8180 C CB . VAL C 1 256 ? 6.659 -208.884 40.673 1.00 25.68 ? 314 VAL E CB 1 ATOM 8181 C CG1 . VAL C 1 256 ? 6.177 -207.753 41.574 1.00 26.71 ? 314 VAL E CG1 1 ATOM 8182 C CG2 . VAL C 1 256 ? 8.175 -208.858 40.559 1.00 24.97 ? 314 VAL E CG2 1 ATOM 8183 N N . ILE C 1 257 ? 4.203 -210.194 42.604 1.00 18.63 ? 315 ILE E N 1 ATOM 8184 C CA . ILE C 1 257 ? 2.777 -210.181 42.900 1.00 19.55 ? 315 ILE E CA 1 ATOM 8185 C C . ILE C 1 257 ? 2.408 -208.847 43.534 1.00 21.39 ? 315 ILE E C 1 ATOM 8186 O O . ILE C 1 257 ? 3.050 -208.411 44.490 1.00 19.77 ? 315 ILE E O 1 ATOM 8187 C CB . ILE C 1 257 ? 2.391 -211.348 43.833 1.00 20.75 ? 315 ILE E CB 1 ATOM 8188 C CG1 . ILE C 1 257 ? 2.581 -212.680 43.099 1.00 24.19 ? 315 ILE E CG1 1 ATOM 8189 C CG2 . ILE C 1 257 ? 0.945 -211.215 44.311 1.00 20.75 ? 315 ILE E CG2 1 ATOM 8190 C CD1 . ILE C 1 257 ? 2.550 -213.894 43.996 1.00 48.50 ? 315 ILE E CD1 1 ATOM 8191 N N . GLU C 1 258 ? 1.385 -208.195 42.989 1.00 20.79 ? 316 GLU E N 1 ATOM 8192 C CA . GLU C 1 258 ? 0.944 -206.906 43.518 1.00 22.75 ? 316 GLU E CA 1 ATOM 8193 C C . GLU C 1 258 ? -0.569 -206.826 43.666 1.00 17.54 ? 316 GLU E C 1 ATOM 8194 O O . GLU C 1 258 ? -1.316 -207.395 42.871 1.00 26.61 ? 316 GLU E O 1 ATOM 8195 C CB . GLU C 1 258 ? 1.437 -205.770 42.620 1.00 21.12 ? 316 GLU E CB 1 ATOM 8196 C CG . GLU C 1 258 ? 2.951 -205.719 42.483 1.00 28.32 ? 316 GLU E CG 1 ATOM 8197 C CD . GLU C 1 258 ? 3.422 -204.605 41.569 1.00 43.67 ? 316 GLU E CD 1 ATOM 8198 O OE1 . GLU C 1 258 ? 4.524 -204.734 40.997 1.00 33.38 ? 316 GLU E OE1 1 ATOM 8199 O OE2 . GLU C 1 258 ? 2.693 -203.601 41.424 1.00 35.25 ? 316 GLU E OE2 1 ATOM 8200 N N . ARG C 1 259 ? -1.005 -206.121 44.705 1.00 20.81 ? 317 ARG E N 1 ATOM 8201 C CA . ARG C 1 259 ? -2.420 -205.860 44.928 1.00 29.39 ? 317 ARG E CA 1 ATOM 8202 C C . ARG C 1 259 ? -2.971 -204.957 43.832 1.00 26.93 ? 317 ARG E C 1 ATOM 8203 O O . ARG C 1 259 ? -2.296 -204.027 43.390 1.00 24.83 ? 317 ARG E O 1 ATOM 8204 C CB . ARG C 1 259 ? -2.639 -205.207 46.296 1.00 26.09 ? 317 ARG E CB 1 ATOM 8205 C CG . ARG C 1 259 ? -2.167 -206.045 47.475 1.00 32.51 ? 317 ARG E CG 1 ATOM 8206 C CD . ARG C 1 259 ? -2.357 -205.313 48.800 0.89 23.19 ? 317 ARG E CD 1 ATOM 8207 N NE . ARG C 1 259 ? -1.409 -204.213 48.969 0.72 30.92 ? 317 ARG E NE 1 ATOM 8208 C CZ . ARG C 1 259 ? -0.148 -204.361 49.368 0.75 34.99 ? 317 ARG E CZ 1 ATOM 8209 N NH1 . ARG C 1 259 ? 0.636 -203.299 49.493 1.00 39.60 ? 317 ARG E NH1 1 ATOM 8210 N NH2 . ARG C 1 259 ? 0.337 -205.567 49.638 0.92 23.62 ? 317 ARG E NH2 1 ATOM 8211 N N . VAL C 1 260 ? -4.194 -205.239 43.397 1.00 24.28 ? 318 VAL E N 1 ATOM 8212 C CA . VAL C 1 260 ? -4.895 -204.375 42.453 1.00 27.63 ? 318 VAL E CA 1 ATOM 8213 C C . VAL C 1 260 ? -6.374 -204.334 42.806 1.00 30.10 ? 318 VAL E C 1 ATOM 8214 O O . VAL C 1 260 ? -6.916 -205.290 43.362 1.00 29.13 ? 318 VAL E O 1 ATOM 8215 C CB . VAL C 1 260 ? -4.730 -204.846 40.991 1.00 20.17 ? 318 VAL E CB 1 ATOM 8216 C CG1 . VAL C 1 260 ? -3.283 -204.718 40.546 1.00 21.13 ? 318 VAL E CG1 1 ATOM 8217 C CG2 . VAL C 1 260 ? -5.226 -206.279 40.821 1.00 26.10 ? 318 VAL E CG2 1 ATOM 8218 N N . GLU C 1 261 ? -7.018 -203.220 42.480 1.00 29.36 ? 319 GLU E N 1 ATOM 8219 C CA . GLU C 1 261 ? -8.442 -203.046 42.733 1.00 31.97 ? 319 GLU E CA 1 ATOM 8220 C C . GLU C 1 261 ? -9.265 -203.518 41.536 1.00 31.81 ? 319 GLU E C 1 ATOM 8221 O O . GLU C 1 261 ? -10.481 -203.684 41.635 1.00 32.87 ? 319 GLU E O 1 ATOM 8222 C CB . GLU C 1 261 ? -8.750 -201.580 43.042 1.00 35.90 ? 319 GLU E CB 1 ATOM 8223 C CG . GLU C 1 261 ? -7.931 -201.005 44.197 1.00 49.37 ? 319 GLU E CG 1 ATOM 8224 C CD . GLU C 1 261 ? -7.961 -199.487 44.244 0.50 61.57 ? 319 GLU E CD 1 ATOM 8225 O OE1 . GLU C 1 261 ? -9.051 -198.903 44.073 0.65 61.82 ? 319 GLU E OE1 1 ATOM 8226 O OE2 . GLU C 1 261 ? -6.889 -198.878 44.450 0.93 66.90 ? 319 GLU E OE2 1 ATOM 8227 N N . SER C 1 262 ? -8.593 -203.733 40.408 1.00 28.58 ? 320 SER E N 1 ATOM 8228 C CA . SER C 1 262 ? -9.261 -204.148 39.180 1.00 25.06 ? 320 SER E CA 1 ATOM 8229 C C . SER C 1 262 ? -8.264 -204.769 38.206 1.00 20.74 ? 320 SER E C 1 ATOM 8230 O O . SER C 1 262 ? -7.055 -204.621 38.366 1.00 24.09 ? 320 SER E O 1 ATOM 8231 C CB . SER C 1 262 ? -9.958 -202.957 38.523 1.00 38.97 ? 320 SER E CB 1 ATOM 8232 O OG . SER C 1 262 ? -9.010 -202.051 37.985 1.00 29.30 ? 320 SER E OG 1 ATOM 8233 N N . LYS C 1 263 ? -8.779 -205.460 37.194 1.00 21.90 ? 321 LYS E N 1 ATOM 8234 C CA . LYS C 1 263 ? -7.937 -206.124 36.200 1.00 24.52 ? 321 LYS E CA 1 ATOM 8235 C C . LYS C 1 263 ? -7.233 -205.117 35.275 1.00 15.15 ? 321 LYS E C 1 ATOM 8236 O O . LYS C 1 263 ? -6.113 -205.360 34.791 1.00 27.55 ? 321 LYS E O 1 ATOM 8237 C CB . LYS C 1 263 ? -8.777 -207.112 35.376 1.00 28.44 ? 321 LYS E CB 1 ATOM 8238 C CG . LYS C 1 263 ? -10.086 -206.541 34.839 1.00 29.91 ? 321 LYS E CG 1 ATOM 8239 C CD . LYS C 1 263 ? -10.784 -207.492 33.867 1.00 42.94 ? 321 LYS E CD 1 ATOM 8240 C CE . LYS C 1 263 ? -11.272 -208.764 34.550 1.00 49.41 ? 321 LYS E CE 1 ATOM 8241 N NZ . LYS C 1 263 ? -12.206 -208.498 35.683 1.00 66.44 ? 321 LYS E NZ 1 ATOM 8242 N N . ALA C 1 264 ? -7.888 -203.984 35.039 1.00 23.08 ? 322 ALA E N 1 ATOM 8243 C CA . ALA C 1 264 ? -7.322 -202.922 34.210 1.00 24.22 ? 322 ALA E CA 1 ATOM 8244 C C . ALA C 1 264 ? -6.014 -202.406 34.805 1.00 18.78 ? 322 ALA E C 1 ATOM 8245 O O . ALA C 1 264 ? -5.062 -202.109 34.078 1.00 20.62 ? 322 ALA E O 1 ATOM 8246 C CB . ALA C 1 264 ? -8.320 -201.782 34.054 1.00 26.87 ? 322 ALA E CB 1 ATOM 8247 N N . GLN C 1 265 ? -5.969 -202.305 36.131 1.00 22.27 ? 323 GLN E N 1 ATOM 8248 C CA . GLN C 1 265 ? -4.758 -201.880 36.824 1.00 22.90 ? 323 GLN E CA 1 ATOM 8249 C C . GLN C 1 265 ? -3.621 -202.858 36.554 1.00 16.72 ? 323 GLN E C 1 ATOM 8250 O O . GLN C 1 265 ? -2.468 -202.458 36.394 1.00 20.25 ? 323 GLN E O 1 ATOM 8251 C CB . GLN C 1 265 ? -5.004 -201.758 38.329 1.00 25.38 ? 323 GLN E CB 1 ATOM 8252 C CG . GLN C 1 265 ? -5.911 -200.598 38.710 1.00 35.92 ? 323 GLN E CG 1 ATOM 8253 C CD . GLN C 1 265 ? -5.996 -200.381 40.211 1.00 47.84 ? 323 GLN E CD 1 ATOM 8254 O OE1 . GLN C 1 265 ? -5.683 -201.272 41.002 1.00 36.63 ? 323 GLN E OE1 1 ATOM 8255 N NE2 . GLN C 1 265 ? -6.417 -199.186 40.610 1.00 36.99 ? 323 GLN E NE2 1 ATOM 8256 N N . CYS C 1 266 ? -3.949 -204.146 36.507 1.00 21.49 ? 324 CYS E N 1 ATOM 8257 C CA . CYS C 1 266 ? -2.955 -205.162 36.185 1.00 21.70 ? 324 CYS E CA 1 ATOM 8258 C C . CYS C 1 266 ? -2.487 -204.999 34.744 1.00 13.08 ? 324 CYS E C 1 ATOM 8259 O O . CYS C 1 266 ? -1.280 -205.038 34.455 1.00 21.97 ? 324 CYS E O 1 ATOM 8260 C CB . CYS C 1 266 ? -3.512 -206.568 36.393 1.00 19.82 ? 324 CYS E CB 1 ATOM 8261 S SG . CYS C 1 266 ? -2.238 -207.842 36.252 1.00 34.21 ? 324 CYS E SG 1 ATOM 8262 N N . TRP C 1 267 ? -3.447 -204.821 33.841 1.00 19.93 ? 325 TRP E N 1 ATOM 8263 C CA . TRP C 1 267 ? -3.117 -204.508 32.452 1.00 20.21 ? 325 TRP E CA 1 ATOM 8264 C C . TRP C 1 267 ? -2.145 -203.332 32.351 1.00 18.02 ? 325 TRP E C 1 ATOM 8265 O O . TRP C 1 267 ? -1.152 -203.406 31.629 1.00 17.24 ? 325 TRP E O 1 ATOM 8266 C CB . TRP C 1 267 ? -4.384 -204.207 31.652 1.00 24.46 ? 325 TRP E CB 1 ATOM 8267 C CG . TRP C 1 267 ? -4.110 -203.700 30.270 1.00 20.80 ? 325 TRP E CG 1 ATOM 8268 C CD1 . TRP C 1 267 ? -3.527 -204.387 29.245 1.00 22.33 ? 325 TRP E CD1 1 ATOM 8269 C CD2 . TRP C 1 267 ? -4.414 -202.396 29.757 1.00 19.90 ? 325 TRP E CD2 1 ATOM 8270 N NE1 . TRP C 1 267 ? -3.446 -203.591 28.126 1.00 22.29 ? 325 TRP E NE1 1 ATOM 8271 C CE2 . TRP C 1 267 ? -3.985 -202.365 28.415 1.00 26.62 ? 325 TRP E CE2 1 ATOM 8272 C CE3 . TRP C 1 267 ? -5.006 -201.253 30.304 1.00 27.31 ? 325 TRP E CE3 1 ATOM 8273 C CZ2 . TRP C 1 267 ? -4.131 -201.235 27.611 1.00 22.07 ? 325 TRP E CZ2 1 ATOM 8274 C CZ3 . TRP C 1 267 ? -5.148 -200.131 29.503 1.00 23.13 ? 325 TRP E CZ3 1 ATOM 8275 C CH2 . TRP C 1 267 ? -4.711 -200.130 28.173 1.00 21.21 ? 325 TRP E CH2 1 ATOM 8276 N N . VAL C 1 268 ? -2.423 -202.253 33.078 1.00 19.86 ? 326 VAL E N 1 ATOM 8277 C CA . VAL C 1 268 ? -1.508 -201.111 33.116 1.00 15.87 ? 326 VAL E CA 1 ATOM 8278 C C . VAL C 1 268 ? -0.151 -201.496 33.708 1.00 16.62 ? 326 VAL E C 1 ATOM 8279 O O . VAL C 1 268 ? 0.902 -201.105 33.194 1.00 17.52 ? 326 VAL E O 1 ATOM 8280 C CB . VAL C 1 268 ? -2.104 -199.941 33.930 1.00 18.89 ? 326 VAL E CB 1 ATOM 8281 C CG1 . VAL C 1 268 ? -1.072 -198.826 34.144 1.00 16.97 ? 326 VAL E CG1 1 ATOM 8282 C CG2 . VAL C 1 268 ? -3.340 -199.386 33.226 1.00 17.60 ? 326 VAL E CG2 1 ATOM 8283 N N . LYS C 1 269 ? -0.177 -202.258 34.796 1.00 18.67 ? 327 LYS E N 1 ATOM 8284 C CA . LYS C 1 269 ? 1.057 -202.690 35.446 1.00 20.44 ? 327 LYS E CA 1 ATOM 8285 C C . LYS C 1 269 ? 1.946 -203.514 34.528 1.00 16.34 ? 327 LYS E C 1 ATOM 8286 O O . LYS C 1 269 ? 3.171 -203.417 34.608 1.00 17.60 ? 327 LYS E O 1 ATOM 8287 C CB . LYS C 1 269 ? 0.748 -203.498 36.706 1.00 22.75 ? 327 LYS E CB 1 ATOM 8288 C CG . LYS C 1 269 ? 0.429 -202.642 37.918 1.00 22.07 ? 327 LYS E CG 1 ATOM 8289 C CD . LYS C 1 269 ? 0.189 -203.499 39.149 1.00 32.76 ? 327 LYS E CD 1 ATOM 8290 C CE . LYS C 1 269 ? -0.217 -202.652 40.344 1.00 29.16 ? 327 LYS E CE 1 ATOM 8291 N NZ . LYS C 1 269 ? 0.870 -201.732 40.772 1.00 31.67 ? 327 LYS E NZ 1 ATOM 8292 N N . THR C 1 270 ? 1.358 -204.341 33.669 1.00 13.50 ? 328 THR E N 1 ATOM 8293 C CA . THR C 1 270 ? 2.197 -205.098 32.741 1.00 16.43 ? 328 THR E CA 1 ATOM 8294 C C . THR C 1 270 ? 2.995 -204.188 31.806 1.00 23.87 ? 328 THR E C 1 ATOM 8295 O O . THR C 1 270 ? 4.012 -204.607 31.259 1.00 20.59 ? 328 THR E O 1 ATOM 8296 C CB . THR C 1 270 ? 1.383 -206.082 31.885 1.00 24.47 ? 328 THR E CB 1 ATOM 8297 O OG1 . THR C 1 270 ? 0.457 -205.367 31.057 1.00 28.78 ? 328 THR E OG1 1 ATOM 8298 C CG2 . THR C 1 270 ? 0.639 -207.064 32.774 1.00 19.19 ? 328 THR E CG2 1 ATOM 8299 N N . PHE C 1 271 ? 2.544 -202.949 31.631 1.00 19.69 ? 329 PHE E N 1 ATOM 8300 C CA . PHE C 1 271 ? 3.259 -201.989 30.795 1.00 14.82 ? 329 PHE E CA 1 ATOM 8301 C C . PHE C 1 271 ? 4.129 -201.052 31.632 1.00 18.71 ? 329 PHE E C 1 ATOM 8302 O O . PHE C 1 271 ? 5.244 -200.708 31.232 1.00 15.76 ? 329 PHE E O 1 ATOM 8303 C CB . PHE C 1 271 ? 2.270 -201.172 29.954 1.00 16.80 ? 329 PHE E CB 1 ATOM 8304 C CG . PHE C 1 271 ? 2.919 -200.102 29.119 1.00 17.39 ? 329 PHE E CG 1 ATOM 8305 C CD1 . PHE C 1 271 ? 3.596 -200.423 27.953 1.00 19.10 ? 329 PHE E CD1 1 ATOM 8306 C CD2 . PHE C 1 271 ? 2.834 -198.773 29.492 1.00 16.51 ? 329 PHE E CD2 1 ATOM 8307 C CE1 . PHE C 1 271 ? 4.187 -199.436 27.184 1.00 19.37 ? 329 PHE E CE1 1 ATOM 8308 C CE2 . PHE C 1 271 ? 3.420 -197.783 28.728 1.00 17.19 ? 329 PHE E CE2 1 ATOM 8309 C CZ . PHE C 1 271 ? 4.098 -198.114 27.572 1.00 18.95 ? 329 PHE E CZ 1 ATOM 8310 N N . GLU C 1 272 ? 3.630 -200.642 32.795 1.00 15.79 ? 330 GLU E N 1 ATOM 8311 C CA . GLU C 1 272 ? 4.305 -199.597 33.564 1.00 20.43 ? 330 GLU E CA 1 ATOM 8312 C C . GLU C 1 272 ? 5.260 -200.062 34.668 1.00 21.54 ? 330 GLU E C 1 ATOM 8313 O O . GLU C 1 272 ? 5.944 -199.231 35.261 1.00 20.15 ? 330 GLU E O 1 ATOM 8314 C CB . GLU C 1 272 ? 3.254 -198.666 34.178 1.00 17.11 ? 330 GLU E CB 1 ATOM 8315 C CG . GLU C 1 272 ? 2.569 -197.788 33.136 1.00 29.36 ? 330 GLU E CG 1 ATOM 8316 C CD . GLU C 1 272 ? 1.628 -196.767 33.739 1.00 36.77 ? 330 GLU E CD 1 ATOM 8317 O OE1 . GLU C 1 272 ? 0.970 -196.044 32.962 1.00 29.26 ? 330 GLU E OE1 1 ATOM 8318 O OE2 . GLU C 1 272 ? 1.549 -196.682 34.984 1.00 38.32 ? 330 GLU E OE2 1 ATOM 8319 N N . ASN C 1 273 ? 5.332 -201.360 34.951 1.00 23.46 ? 331 ASN E N 1 ATOM 8320 C CA . ASN C 1 273 ? 6.241 -201.823 36.001 1.00 18.62 ? 331 ASN E CA 1 ATOM 8321 C C . ASN C 1 273 ? 7.692 -201.612 35.574 1.00 15.33 ? 331 ASN E C 1 ATOM 8322 O O . ASN C 1 273 ? 7.994 -201.564 34.384 1.00 16.97 ? 331 ASN E O 1 ATOM 8323 C CB . ASN C 1 273 ? 5.991 -203.295 36.349 1.00 18.31 ? 331 ASN E CB 1 ATOM 8324 C CG . ASN C 1 273 ? 6.635 -204.250 35.368 1.00 20.78 ? 331 ASN E CG 1 ATOM 8325 O OD1 . ASN C 1 273 ? 7.840 -204.501 35.428 1.00 20.02 ? 331 ASN E OD1 1 ATOM 8326 N ND2 . ASN C 1 273 ? 5.832 -204.803 34.467 1.00 16.70 ? 331 ASN E ND2 1 ATOM 8327 N N . ASP C 1 274 ? 8.586 -201.491 36.550 1.00 16.09 ? 332 ASP E N 1 ATOM 8328 C CA . ASP C 1 274 ? 9.954 -201.047 36.287 1.00 22.52 ? 332 ASP E CA 1 ATOM 8329 C C . ASP C 1 274 ? 10.819 -202.084 35.570 1.00 21.86 ? 332 ASP E C 1 ATOM 8330 O O . ASP C 1 274 ? 11.987 -201.822 35.284 1.00 23.48 ? 332 ASP E O 1 ATOM 8331 C CB . ASP C 1 274 ? 10.634 -200.639 37.601 1.00 26.63 ? 332 ASP E CB 1 ATOM 8332 C CG . ASP C 1 274 ? 10.698 -201.775 38.616 1.00 45.29 ? 332 ASP E CG 1 ATOM 8333 O OD1 . ASP C 1 274 ? 10.399 -202.933 38.256 1.00 42.82 ? 332 ASP E OD1 1 ATOM 8334 O OD2 . ASP C 1 274 ? 11.058 -201.504 39.782 1.00 48.03 ? 332 ASP E OD2 1 ATOM 8335 N N . GLY C 1 275 ? 10.248 -203.249 35.280 1.00 15.24 ? 333 GLY E N 1 ATOM 8336 C CA . GLY C 1 275 ? 10.987 -204.321 34.636 1.00 16.81 ? 333 GLY E CA 1 ATOM 8337 C C . GLY C 1 275 ? 10.687 -204.477 33.155 1.00 19.63 ? 333 GLY E C 1 ATOM 8338 O O . GLY C 1 275 ? 11.351 -205.249 32.468 1.00 15.55 ? 333 GLY E O 1 ATOM 8339 N N . VAL C 1 276 ? 9.694 -203.744 32.659 1.00 17.64 ? 334 VAL E N 1 ATOM 8340 C CA . VAL C 1 276 ? 9.271 -203.869 31.265 1.00 17.56 ? 334 VAL E CA 1 ATOM 8341 C C . VAL C 1 276 ? 10.404 -203.503 30.311 1.00 15.23 ? 334 VAL E C 1 ATOM 8342 O O . VAL C 1 276 ? 11.202 -202.613 30.600 1.00 20.37 ? 334 VAL E O 1 ATOM 8343 C CB . VAL C 1 276 ? 8.049 -202.980 30.974 1.00 15.88 ? 334 VAL E CB 1 ATOM 8344 C CG1 . VAL C 1 276 ? 7.645 -203.063 29.508 1.00 20.08 ? 334 VAL E CG1 1 ATOM 8345 C CG2 . VAL C 1 276 ? 6.889 -203.398 31.850 1.00 24.11 ? 334 VAL E CG2 1 ATOM 8346 N N . ALA C 1 277 ? 10.471 -204.198 29.178 1.00 19.53 ? 335 ALA E N 1 ATOM 8347 C CA . ALA C 1 277 ? 11.494 -203.938 28.168 1.00 18.33 ? 335 ALA E CA 1 ATOM 8348 C C . ALA C 1 277 ? 11.554 -202.454 27.803 1.00 21.34 ? 335 ALA E C 1 ATOM 8349 O O . ALA C 1 277 ? 10.539 -201.854 27.453 1.00 21.51 ? 335 ALA E O 1 ATOM 8350 C CB . ALA C 1 277 ? 11.228 -204.774 26.926 1.00 25.43 ? 335 ALA E CB 1 ATOM 8351 N N . SER C 1 278 ? 12.746 -201.870 27.890 1.00 22.00 ? 336 SER E N 1 ATOM 8352 C CA . SER C 1 278 ? 12.922 -200.445 27.637 1.00 24.72 ? 336 SER E CA 1 ATOM 8353 C C . SER C 1 278 ? 14.315 -200.140 27.105 1.00 20.28 ? 336 SER E C 1 ATOM 8354 O O . SER C 1 278 ? 15.302 -200.713 27.563 1.00 21.11 ? 336 SER E O 1 ATOM 8355 C CB . SER C 1 278 ? 12.670 -199.643 28.915 1.00 22.77 ? 336 SER E CB 1 ATOM 8356 O OG . SER C 1 278 ? 13.009 -198.279 28.734 1.00 24.70 ? 336 SER E OG 1 ATOM 8357 N N . ASP C 1 279 ? 14.383 -199.225 26.143 1.00 16.77 ? 337 ASP E N 1 ATOM 8358 C CA . ASP C 1 279 ? 15.645 -198.841 25.526 1.00 19.13 ? 337 ASP E CA 1 ATOM 8359 C C . ASP C 1 279 ? 16.137 -197.491 26.040 1.00 19.63 ? 337 ASP E C 1 ATOM 8360 O O . ASP C 1 279 ? 17.106 -196.939 25.522 1.00 18.69 ? 337 ASP E O 1 ATOM 8361 C CB . ASP C 1 279 ? 15.491 -198.806 24.004 1.00 23.97 ? 337 ASP E CB 1 ATOM 8362 C CG . ASP C 1 279 ? 15.014 -200.132 23.439 1.00 27.83 ? 337 ASP E CG 1 ATOM 8363 O OD1 . ASP C 1 279 ? 15.175 -201.163 24.126 1.00 31.39 ? 337 ASP E OD1 1 ATOM 8364 O OD2 . ASP C 1 279 ? 14.479 -200.146 22.310 1.00 25.43 ? 337 ASP E OD2 1 ATOM 8365 N N . GLN C 1 280 ? 15.470 -196.964 27.062 1.00 19.45 ? 338 GLN E N 1 ATOM 8366 C CA . GLN C 1 280 ? 15.851 -195.678 27.641 1.00 17.83 ? 338 GLN E CA 1 ATOM 8367 C C . GLN C 1 280 ? 17.231 -195.775 28.293 1.00 24.96 ? 338 GLN E C 1 ATOM 8368 O O . GLN C 1 280 ? 17.548 -196.794 28.906 1.00 27.63 ? 338 GLN E O 1 ATOM 8369 C CB . GLN C 1 280 ? 14.814 -195.227 28.675 1.00 19.92 ? 338 GLN E CB 1 ATOM 8370 C CG . GLN C 1 280 ? 15.000 -193.796 29.176 1.00 23.58 ? 338 GLN E CG 1 ATOM 8371 C CD . GLN C 1 280 ? 14.588 -192.750 28.152 1.00 25.43 ? 338 GLN E CD 1 ATOM 8372 O OE1 . GLN C 1 280 ? 14.075 -193.077 27.081 1.00 19.39 ? 338 GLN E OE1 1 ATOM 8373 N NE2 . GLN C 1 280 ? 14.815 -191.482 28.478 1.00 21.02 ? 338 GLN E NE2 1 ATOM 8374 N N . PRO C 1 281 ? 18.061 -194.723 28.157 1.00 24.20 ? 339 PRO E N 1 ATOM 8375 C CA . PRO C 1 281 ? 19.356 -194.673 28.850 1.00 36.52 ? 339 PRO E CA 1 ATOM 8376 C C . PRO C 1 281 ? 19.239 -194.973 30.339 1.00 33.63 ? 339 PRO E C 1 ATOM 8377 O O . PRO C 1 281 ? 18.330 -194.421 30.960 1.00 29.11 ? 339 PRO E O 1 ATOM 8378 C CB . PRO C 1 281 ? 19.815 -193.231 28.636 1.00 32.53 ? 339 PRO E CB 1 ATOM 8379 C CG . PRO C 1 281 ? 19.167 -192.810 27.384 1.00 32.66 ? 339 PRO E CG 1 ATOM 8380 C CD . PRO C 1 281 ? 17.874 -193.561 27.270 1.00 21.88 ? 339 PRO E CD 1 ATOM 8381 N N . ASP C 1 289 ? 25.253 -194.028 26.751 1.00 48.67 ? 360 ASP E N 1 ATOM 8382 C CA . ASP C 1 289 ? 24.583 -195.292 27.034 1.00 48.19 ? 360 ASP E CA 1 ATOM 8383 C C . ASP C 1 289 ? 23.307 -195.419 26.208 1.00 44.88 ? 360 ASP E C 1 ATOM 8384 O O . ASP C 1 289 ? 22.399 -194.594 26.321 1.00 39.99 ? 360 ASP E O 1 ATOM 8385 C CB . ASP C 1 289 ? 24.262 -195.405 28.525 1.00 64.03 ? 360 ASP E CB 1 ATOM 8386 C CG . ASP C 1 289 ? 23.726 -196.773 28.906 1.00 56.20 ? 360 ASP E CG 1 ATOM 8387 O OD1 . ASP C 1 289 ? 24.284 -197.787 28.436 1.00 56.37 ? 360 ASP E OD1 1 ATOM 8388 O OD2 . ASP C 1 289 ? 22.743 -196.832 29.675 1.00 55.06 ? 360 ASP E OD2 1 ATOM 8389 N N . GLN C 1 290 ? 23.249 -196.459 25.381 1.00 36.92 ? 361 GLN E N 1 ATOM 8390 C CA . GLN C 1 290 ? 22.120 -196.680 24.487 1.00 35.77 ? 361 GLN E CA 1 ATOM 8391 C C . GLN C 1 290 ? 21.728 -198.154 24.493 1.00 35.02 ? 361 GLN E C 1 ATOM 8392 O O . GLN C 1 290 ? 22.067 -198.894 23.571 1.00 32.15 ? 361 GLN E O 1 ATOM 8393 C CB . GLN C 1 290 ? 22.469 -196.222 23.069 1.00 30.17 ? 361 GLN E CB 1 ATOM 8394 C CG . GLN C 1 290 ? 22.955 -194.783 23.007 1.00 33.24 ? 361 GLN E CG 1 ATOM 8395 C CD . GLN C 1 290 ? 22.983 -194.231 21.595 1.00 42.54 ? 361 GLN E CD 1 ATOM 8396 O OE1 . GLN C 1 290 ? 22.902 -194.977 20.619 1.00 31.94 ? 361 GLN E OE1 1 ATOM 8397 N NE2 . GLN C 1 290 ? 23.093 -192.913 21.480 1.00 37.73 ? 361 GLN E NE2 1 ATOM 8398 N N . PRO C 1 291 ? 21.005 -198.584 25.540 1.00 31.76 ? 362 PRO E N 1 ATOM 8399 C CA . PRO C 1 291 ? 20.670 -200.001 25.718 1.00 30.26 ? 362 PRO E CA 1 ATOM 8400 C C . PRO C 1 291 ? 19.616 -200.512 24.740 1.00 35.45 ? 362 PRO E C 1 ATOM 8401 O O . PRO C 1 291 ? 18.662 -199.798 24.417 1.00 24.29 ? 362 PRO E O 1 ATOM 8402 C CB . PRO C 1 291 ? 20.141 -200.052 27.155 1.00 31.45 ? 362 PRO E CB 1 ATOM 8403 C CG . PRO C 1 291 ? 19.583 -198.704 27.392 1.00 34.39 ? 362 PRO E CG 1 ATOM 8404 C CD . PRO C 1 291 ? 20.446 -197.749 26.619 1.00 30.09 ? 362 PRO E CD 1 ATOM 8405 N N . HIS C 1 292 ? 19.806 -201.745 24.279 1.00 30.95 ? 363 HIS E N 1 ATOM 8406 C CA . HIS C 1 292 ? 18.833 -202.432 23.439 1.00 26.21 ? 363 HIS E CA 1 ATOM 8407 C C . HIS C 1 292 ? 18.300 -203.653 24.181 1.00 32.19 ? 363 HIS E C 1 ATOM 8408 O O . HIS C 1 292 ? 18.983 -204.670 24.298 1.00 32.44 ? 363 HIS E O 1 ATOM 8409 C CB . HIS C 1 292 ? 19.459 -202.845 22.105 1.00 25.41 ? 363 HIS E CB 1 ATOM 8410 C CG . HIS C 1 292 ? 19.883 -201.689 21.253 1.00 41.92 ? 363 HIS E CG 1 ATOM 8411 N ND1 . HIS C 1 292 ? 20.577 -201.848 20.073 1.00 40.14 ? 363 HIS E ND1 1 ATOM 8412 C CD2 . HIS C 1 292 ? 19.708 -200.355 21.408 1.00 44.65 ? 363 HIS E CD2 1 ATOM 8413 C CE1 . HIS C 1 292 ? 20.814 -200.663 19.540 1.00 47.38 ? 363 HIS E CE1 1 ATOM 8414 N NE2 . HIS C 1 292 ? 20.297 -199.740 20.331 1.00 44.41 ? 363 HIS E NE2 1 ATOM 8415 N N . SER C 1 293 ? 17.078 -203.540 24.687 1.00 27.76 ? 364 SER E N 1 ATOM 8416 C CA . SER C 1 293 ? 16.464 -204.611 25.459 1.00 26.39 ? 364 SER E CA 1 ATOM 8417 C C . SER C 1 293 ? 16.122 -205.815 24.588 1.00 28.88 ? 364 SER E C 1 ATOM 8418 O O . SER C 1 293 ? 16.039 -206.941 25.077 1.00 31.97 ? 364 SER E O 1 ATOM 8419 C CB . SER C 1 293 ? 15.201 -204.104 26.148 1.00 20.39 ? 364 SER E CB 1 ATOM 8420 O OG . SER C 1 293 ? 14.179 -203.863 25.197 1.00 25.23 ? 364 SER E OG 1 ATOM 8421 N N . GLY C 1 294 ? 15.912 -205.571 23.299 1.00 25.70 ? 365 GLY E N 1 ATOM 8422 C CA . GLY C 1 294 ? 15.537 -206.627 22.375 1.00 21.75 ? 365 GLY E CA 1 ATOM 8423 C C . GLY C 1 294 ? 14.189 -207.249 22.699 1.00 25.64 ? 365 GLY E C 1 ATOM 8424 O O . GLY C 1 294 ? 13.876 -208.343 22.228 1.00 21.71 ? 365 GLY E O 1 ATOM 8425 N N . GLY C 1 295 ? 13.390 -206.551 23.502 1.00 18.00 ? 366 GLY E N 1 ATOM 8426 C CA . GLY C 1 295 ? 12.086 -207.047 23.909 1.00 19.51 ? 366 GLY E CA 1 ATOM 8427 C C . GLY C 1 295 ? 12.107 -207.893 25.172 1.00 13.31 ? 366 GLY E C 1 ATOM 8428 O O . GLY C 1 295 ? 11.069 -208.403 25.594 1.00 28.08 ? 366 GLY E O 1 ATOM 8429 N N . VAL C 1 296 ? 13.281 -208.043 25.779 1.00 24.04 ? 367 VAL E N 1 ATOM 8430 C CA . VAL C 1 296 ? 13.410 -208.793 27.028 1.00 25.47 ? 367 VAL E CA 1 ATOM 8431 C C . VAL C 1 296 ? 12.974 -207.952 28.226 1.00 23.24 ? 367 VAL E C 1 ATOM 8432 O O . VAL C 1 296 ? 13.408 -206.811 28.374 1.00 22.97 ? 367 VAL E O 1 ATOM 8433 C CB . VAL C 1 296 ? 14.863 -209.259 27.257 1.00 22.90 ? 367 VAL E CB 1 ATOM 8434 C CG1 . VAL C 1 296 ? 15.012 -209.937 28.619 1.00 29.71 ? 367 VAL E CG1 1 ATOM 8435 C CG2 . VAL C 1 296 ? 15.300 -210.199 26.151 1.00 26.71 ? 367 VAL E CG2 1 ATOM 8436 N N . GLY C 1 297 ? 12.135 -208.517 29.089 1.00 26.66 ? 368 GLY E N 1 ATOM 8437 C CA . GLY C 1 297 ? 11.743 -207.833 30.308 1.00 20.05 ? 368 GLY E CA 1 ATOM 8438 C C . GLY C 1 297 ? 10.478 -208.380 30.935 1.00 22.04 ? 368 GLY E C 1 ATOM 8439 O O . GLY C 1 297 ? 9.864 -209.312 30.418 1.00 20.37 ? 368 GLY E O 1 ATOM 8440 N N . ARG C 1 298 ? 10.092 -207.791 32.062 1.00 21.04 ? 369 ARG E N 1 ATOM 8441 C CA . ARG C 1 298 ? 8.888 -208.201 32.772 1.00 17.71 ? 369 ARG E CA 1 ATOM 8442 C C . ARG C 1 298 ? 7.659 -207.686 32.034 1.00 21.58 ? 369 ARG E C 1 ATOM 8443 O O . ARG C 1 298 ? 6.950 -206.802 32.515 1.00 19.54 ? 369 ARG E O 1 ATOM 8444 C CB . ARG C 1 298 ? 8.914 -207.689 34.214 1.00 19.90 ? 369 ARG E CB 1 ATOM 8445 C CG . ARG C 1 298 ? 7.845 -208.298 35.110 1.00 19.65 ? 369 ARG E CG 1 ATOM 8446 C CD . ARG C 1 298 ? 7.873 -207.696 36.507 1.00 20.99 ? 369 ARG E CD 1 ATOM 8447 N NE . ARG C 1 298 ? 9.167 -207.885 37.166 1.00 18.94 ? 369 ARG E NE 1 ATOM 8448 C CZ . ARG C 1 298 ? 9.882 -206.927 37.757 1.00 23.02 ? 369 ARG E CZ 1 ATOM 8449 N NH1 . ARG C 1 298 ? 9.455 -205.669 37.796 1.00 21.66 ? 369 ARG E NH1 1 ATOM 8450 N NH2 . ARG C 1 298 ? 11.043 -207.232 38.319 1.00 21.82 ? 369 ARG E NH2 1 ATOM 8451 N N . ASN C 1 299 ? 7.416 -208.254 30.854 1.00 19.11 ? 370 ASN E N 1 ATOM 8452 C CA . ASN C 1 299 ? 6.366 -207.787 29.958 1.00 20.66 ? 370 ASN E CA 1 ATOM 8453 C C . ASN C 1 299 ? 5.040 -208.516 30.103 1.00 30.32 ? 370 ASN E C 1 ATOM 8454 O O . ASN C 1 299 ? 4.045 -208.113 29.500 1.00 21.58 ? 370 ASN E O 1 ATOM 8455 C CB . ASN C 1 299 ? 6.835 -207.921 28.508 1.00 21.15 ? 370 ASN E CB 1 ATOM 8456 C CG . ASN C 1 299 ? 8.191 -207.297 28.275 1.00 19.39 ? 370 ASN E CG 1 ATOM 8457 O OD1 . ASN C 1 299 ? 8.538 -206.288 28.889 1.00 21.71 ? 370 ASN E OD1 1 ATOM 8458 N ND2 . ASN C 1 299 ? 8.973 -207.899 27.387 1.00 21.32 ? 370 ASN E ND2 1 ATOM 8459 N N . TYR C 1 300 ? 5.027 -209.584 30.895 1.00 20.69 ? 371 TYR E N 1 ATOM 8460 C CA . TYR C 1 300 ? 3.882 -210.485 30.942 1.00 18.56 ? 371 TYR E CA 1 ATOM 8461 C C . TYR C 1 300 ? 3.262 -210.520 32.312 1.00 21.94 ? 371 TYR E C 1 ATOM 8462 O O . TYR C 1 300 ? 3.961 -210.473 33.324 1.00 25.19 ? 371 TYR E O 1 ATOM 8463 C CB . TYR C 1 300 ? 4.311 -211.890 30.532 1.00 17.10 ? 371 TYR E CB 1 ATOM 8464 C CG . TYR C 1 300 ? 5.204 -211.862 29.328 1.00 15.10 ? 371 TYR E CG 1 ATOM 8465 C CD1 . TYR C 1 300 ? 4.670 -211.756 28.057 1.00 20.52 ? 371 TYR E CD1 1 ATOM 8466 C CD2 . TYR C 1 300 ? 6.581 -211.901 29.463 1.00 18.54 ? 371 TYR E CD2 1 ATOM 8467 C CE1 . TYR C 1 300 ? 5.479 -211.706 26.952 1.00 11.69 ? 371 TYR E CE1 1 ATOM 8468 C CE2 . TYR C 1 300 ? 7.403 -211.856 28.359 1.00 18.45 ? 371 TYR E CE2 1 ATOM 8469 C CZ . TYR C 1 300 ? 6.843 -211.757 27.102 1.00 14.68 ? 371 TYR E CZ 1 ATOM 8470 O OH . TYR C 1 300 ? 7.643 -211.708 25.982 1.00 23.77 ? 371 TYR E OH 1 ATOM 8471 N N . GLY C 1 301 ? 1.942 -210.603 32.354 1.00 20.50 ? 372 GLY E N 1 ATOM 8472 C CA . GLY C 1 301 ? 1.296 -210.764 33.632 1.00 20.39 ? 372 GLY E CA 1 ATOM 8473 C C . GLY C 1 301 ? -0.137 -211.209 33.537 1.00 21.96 ? 372 GLY E C 1 ATOM 8474 O O . GLY C 1 301 ? -0.663 -211.386 32.444 1.00 19.81 ? 372 GLY E O 1 ATOM 8475 N N . PHE C 1 302 ? -0.769 -211.415 34.685 1.00 21.46 ? 373 PHE E N 1 ATOM 8476 C CA . PHE C 1 302 ? -2.202 -211.667 34.675 1.00 17.19 ? 373 PHE E CA 1 ATOM 8477 C C . PHE C 1 302 ? -2.889 -211.246 35.958 1.00 13.77 ? 373 PHE E C 1 ATOM 8478 O O . PHE C 1 302 ? -2.292 -211.226 37.042 1.00 23.72 ? 373 PHE E O 1 ATOM 8479 C CB . PHE C 1 302 ? -2.507 -213.149 34.387 1.00 25.98 ? 373 PHE E CB 1 ATOM 8480 C CG . PHE C 1 302 ? -1.879 -214.119 35.350 1.00 24.01 ? 373 PHE E CG 1 ATOM 8481 C CD1 . PHE C 1 302 ? -2.461 -214.386 36.581 1.00 21.21 ? 373 PHE E CD1 1 ATOM 8482 C CD2 . PHE C 1 302 ? -0.726 -214.803 34.998 1.00 19.99 ? 373 PHE E CD2 1 ATOM 8483 C CE1 . PHE C 1 302 ? -1.885 -215.295 37.452 1.00 25.12 ? 373 PHE E CE1 1 ATOM 8484 C CE2 . PHE C 1 302 ? -0.148 -215.710 35.864 1.00 24.68 ? 373 PHE E CE2 1 ATOM 8485 C CZ . PHE C 1 302 ? -0.728 -215.957 37.092 1.00 18.01 ? 373 PHE E CZ 1 ATOM 8486 N N . TYR C 1 303 ? -4.153 -210.875 35.798 1.00 16.42 ? 374 TYR E N 1 ATOM 8487 C CA . TYR C 1 303 ? -5.035 -210.608 36.912 1.00 17.67 ? 374 TYR E CA 1 ATOM 8488 C C . TYR C 1 303 ? -5.665 -211.908 37.366 1.00 26.13 ? 374 TYR E C 1 ATOM 8489 O O . TYR C 1 303 ? -6.110 -212.716 36.536 1.00 23.90 ? 374 TYR E O 1 ATOM 8490 C CB . TYR C 1 303 ? -6.121 -209.608 36.521 1.00 12.11 ? 374 TYR E CB 1 ATOM 8491 C CG . TYR C 1 303 ? -7.242 -209.486 37.534 1.00 21.51 ? 374 TYR E CG 1 ATOM 8492 C CD1 . TYR C 1 303 ? -7.148 -208.604 38.604 1.00 25.81 ? 374 TYR E CD1 1 ATOM 8493 C CD2 . TYR C 1 303 ? -8.396 -210.251 37.417 1.00 25.68 ? 374 TYR E CD2 1 ATOM 8494 C CE1 . TYR C 1 303 ? -8.172 -208.487 39.527 1.00 23.65 ? 374 TYR E CE1 1 ATOM 8495 C CE2 . TYR C 1 303 ? -9.423 -210.143 38.338 1.00 23.49 ? 374 TYR E CE2 1 ATOM 8496 C CZ . TYR C 1 303 ? -9.306 -209.259 39.390 1.00 31.95 ? 374 TYR E CZ 1 ATOM 8497 O OH . TYR C 1 303 ? -10.324 -209.145 40.310 1.00 34.46 ? 374 TYR E OH 1 ATOM 8498 N N . TYR C 1 304 ? -5.684 -212.105 38.682 1.00 19.54 ? 375 TYR E N 1 ATOM 8499 C CA . TYR C 1 304 ? -6.375 -213.244 39.275 1.00 28.14 ? 375 TYR E CA 1 ATOM 8500 C C . TYR C 1 304 ? -6.974 -212.891 40.632 1.00 31.71 ? 375 TYR E C 1 ATOM 8501 O O . TYR C 1 304 ? -6.590 -211.903 41.260 1.00 30.38 ? 375 TYR E O 1 ATOM 8502 C CB . TYR C 1 304 ? -5.429 -214.439 39.420 1.00 21.59 ? 375 TYR E CB 1 ATOM 8503 C CG . TYR C 1 304 ? -4.332 -214.271 40.453 1.00 26.28 ? 375 TYR E CG 1 ATOM 8504 C CD1 . TYR C 1 304 ? -3.145 -213.624 40.136 1.00 23.51 ? 375 TYR E CD1 1 ATOM 8505 C CD2 . TYR C 1 304 ? -4.474 -214.782 41.737 1.00 30.58 ? 375 TYR E CD2 1 ATOM 8506 C CE1 . TYR C 1 304 ? -2.137 -213.478 41.070 1.00 27.93 ? 375 TYR E CE1 1 ATOM 8507 C CE2 . TYR C 1 304 ? -3.470 -214.640 42.680 1.00 28.48 ? 375 TYR E CE2 1 ATOM 8508 C CZ . TYR C 1 304 ? -2.304 -213.987 42.340 1.00 26.50 ? 375 TYR E CZ 1 ATOM 8509 O OH . TYR C 1 304 ? -1.298 -213.840 43.267 1.00 29.00 ? 375 TYR E OH 1 ATOM 8510 N N . VAL C 1 305 ? -7.927 -213.709 41.067 1.00 30.37 ? 376 VAL E N 1 ATOM 8511 C CA . VAL C 1 305 ? -8.575 -213.545 42.363 1.00 33.19 ? 376 VAL E CA 1 ATOM 8512 C C . VAL C 1 305 ? -8.028 -214.592 43.325 1.00 37.77 ? 376 VAL E C 1 ATOM 8513 O O . VAL C 1 305 ? -8.061 -215.787 43.028 1.00 38.97 ? 376 VAL E O 1 ATOM 8514 C CB . VAL C 1 305 ? -10.107 -213.684 42.255 1.00 37.84 ? 376 VAL E CB 1 ATOM 8515 C CG1 . VAL C 1 305 ? -10.775 -213.377 43.593 1.00 44.03 ? 376 VAL E CG1 1 ATOM 8516 C CG2 . VAL C 1 305 ? -10.649 -212.767 41.168 1.00 39.74 ? 376 VAL E CG2 1 ATOM 8517 N N . ASP C 1 306 ? -7.521 -214.148 44.471 1.00 38.16 ? 377 ASP E N 1 ATOM 8518 C CA . ASP C 1 306 ? -6.925 -215.068 45.435 1.00 45.73 ? 377 ASP E CA 1 ATOM 8519 C C . ASP C 1 306 ? -8.008 -215.789 46.235 1.00 41.57 ? 377 ASP E C 1 ATOM 8520 O O . ASP C 1 306 ? -9.198 -215.516 46.071 1.00 37.80 ? 377 ASP E O 1 ATOM 8521 C CB . ASP C 1 306 ? -5.957 -214.331 46.373 1.00 42.39 ? 377 ASP E CB 1 ATOM 8522 C CG . ASP C 1 306 ? -6.600 -213.152 47.089 1.00 55.40 ? 377 ASP E CG 1 ATOM 8523 O OD1 . ASP C 1 306 ? -7.838 -213.134 47.252 1.00 52.85 ? 377 ASP E OD1 1 ATOM 8524 O OD2 . ASP C 1 306 ? -5.853 -212.239 47.501 1.00 55.65 ? 377 ASP E OD2 1 ATOM 8525 N N . THR C 1 307 ? -7.586 -216.708 47.098 1.00 60.85 ? 378 THR E N 1 ATOM 8526 C CA . THR C 1 307 ? -8.512 -217.533 47.868 1.00 52.58 ? 378 THR E CA 1 ATOM 8527 C C . THR C 1 307 ? -9.419 -216.715 48.788 1.00 54.96 ? 378 THR E C 1 ATOM 8528 O O . THR C 1 307 ? -10.481 -217.187 49.196 1.00 55.61 ? 378 THR E O 1 ATOM 8529 C CB . THR C 1 307 ? -7.750 -218.564 48.723 1.00 66.50 ? 378 THR E CB 1 ATOM 8530 O OG1 . THR C 1 307 ? -6.718 -217.905 49.467 1.00 63.09 ? 378 THR E OG1 1 ATOM 8531 C CG2 . THR C 1 307 ? -7.129 -219.639 47.838 1.00 56.08 ? 378 THR E CG2 1 ATOM 8532 N N . THR C 1 308 ? -9.001 -215.493 49.107 1.00 48.58 ? 379 THR E N 1 ATOM 8533 C CA . THR C 1 308 ? -9.765 -214.626 50.002 1.00 44.26 ? 379 THR E CA 1 ATOM 8534 C C . THR C 1 308 ? -10.656 -213.651 49.230 1.00 46.43 ? 379 THR E C 1 ATOM 8535 O O . THR C 1 308 ? -11.341 -212.821 49.831 1.00 52.34 ? 379 THR E O 1 ATOM 8536 C CB . THR C 1 308 ? -8.836 -213.823 50.933 1.00 58.36 ? 379 THR E CB 1 ATOM 8537 O OG1 . THR C 1 308 ? -8.126 -212.834 50.176 1.00 56.52 ? 379 THR E OG1 1 ATOM 8538 C CG2 . THR C 1 308 ? -7.843 -214.749 51.629 1.00 44.46 ? 379 THR E CG2 1 ATOM 8539 N N . GLY C 1 309 ? -10.637 -213.746 47.903 1.00 48.49 ? 380 GLY E N 1 ATOM 8540 C CA . GLY C 1 309 ? -11.530 -212.963 47.065 1.00 48.57 ? 380 GLY E CA 1 ATOM 8541 C C . GLY C 1 309 ? -10.981 -211.623 46.605 1.00 50.16 ? 380 GLY E C 1 ATOM 8542 O O . GLY C 1 309 ? -11.674 -210.874 45.916 1.00 50.17 ? 380 GLY E O 1 ATOM 8543 N N . GLU C 1 310 ? -9.740 -211.318 46.977 1.00 43.17 ? 381 GLU E N 1 ATOM 8544 C CA . GLU C 1 310 ? -9.122 -210.043 46.615 1.00 41.90 ? 381 GLU E CA 1 ATOM 8545 C C . GLU C 1 310 ? -8.365 -210.140 45.294 1.00 33.55 ? 381 GLU E C 1 ATOM 8546 O O . GLU C 1 310 ? -7.841 -211.197 44.942 1.00 35.35 ? 381 GLU E O 1 ATOM 8547 C CB . GLU C 1 310 ? -8.178 -209.573 47.723 1.00 50.09 ? 381 GLU E CB 1 ATOM 8548 C CG . GLU C 1 310 ? -8.881 -209.260 49.032 1.00 62.67 ? 381 GLU E CG 1 ATOM 8549 C CD . GLU C 1 310 ? -8.110 -208.274 49.888 1.00 91.47 ? 381 GLU E CD 1 ATOM 8550 O OE1 . GLU C 1 310 ? -8.743 -207.360 50.458 1.00 94.48 ? 381 GLU E OE1 1 ATOM 8551 O OE2 . GLU C 1 310 ? -6.873 -208.414 49.993 1.00 82.62 ? 381 GLU E OE2 1 ATOM 8552 N N . GLY C 1 311 ? -8.309 -209.024 44.573 1.00 30.86 ? 382 GLY E N 1 ATOM 8553 C CA . GLY C 1 311 ? -7.671 -208.981 43.270 1.00 28.83 ? 382 GLY E CA 1 ATOM 8554 C C . GLY C 1 311 ? -6.161 -208.896 43.359 1.00 21.80 ? 382 GLY E C 1 ATOM 8555 O O . GLY C 1 311 ? -5.618 -208.147 44.171 1.00 24.55 ? 382 GLY E O 1 ATOM 8556 N N . LYS C 1 312 ? -5.486 -209.669 42.515 1.00 19.72 ? 383 LYS E N 1 ATOM 8557 C CA . LYS C 1 312 ? -4.031 -209.675 42.468 1.00 19.25 ? 383 LYS E CA 1 ATOM 8558 C C . LYS C 1 312 ? -3.531 -209.629 41.031 1.00 19.61 ? 383 LYS E C 1 ATOM 8559 O O . LYS C 1 312 ? -4.205 -210.091 40.101 1.00 20.80 ? 383 LYS E O 1 ATOM 8560 C CB . LYS C 1 312 ? -3.476 -210.915 43.176 1.00 26.67 ? 383 LYS E CB 1 ATOM 8561 C CG . LYS C 1 312 ? -3.731 -210.946 44.676 1.00 29.22 ? 383 LYS E CG 1 ATOM 8562 C CD . LYS C 1 312 ? -2.607 -210.280 45.455 1.00 32.76 ? 383 LYS E CD 1 ATOM 8563 C CE . LYS C 1 312 ? -2.908 -210.247 46.946 1.00 38.26 ? 383 LYS E CE 1 ATOM 8564 N NZ . LYS C 1 312 ? -3.250 -211.594 47.483 1.00 42.64 ? 383 LYS E NZ 1 ATOM 8565 N N . CYS C 1 313 ? -2.343 -209.054 40.872 1.00 20.09 ? 384 CYS E N 1 ATOM 8566 C CA . CYS C 1 313 ? -1.656 -208.989 39.592 1.00 17.75 ? 384 CYS E CA 1 ATOM 8567 C C . CYS C 1 313 ? -0.319 -209.709 39.696 1.00 20.25 ? 384 CYS E C 1 ATOM 8568 O O . CYS C 1 313 ? 0.516 -209.365 40.539 1.00 27.81 ? 384 CYS E O 1 ATOM 8569 C CB . CYS C 1 313 ? -1.441 -207.536 39.160 1.00 19.17 ? 384 CYS E CB 1 ATOM 8570 S SG . CYS C 1 313 ? -0.712 -207.353 37.518 1.00 30.33 ? 384 CYS E SG 1 ATOM 8571 N N . ALA C 1 314 ? -0.133 -210.714 38.843 1.00 21.36 ? 385 ALA E N 1 ATOM 8572 C CA . ALA C 1 314 ? 1.125 -211.453 38.773 1.00 17.83 ? 385 ALA E CA 1 ATOM 8573 C C . ALA C 1 314 ? 1.907 -211.012 37.544 1.00 20.16 ? 385 ALA E C 1 ATOM 8574 O O . ALA C 1 314 ? 1.362 -210.984 36.442 1.00 20.54 ? 385 ALA E O 1 ATOM 8575 C CB . ALA C 1 314 ? 0.869 -212.949 38.734 1.00 23.02 ? 385 ALA E CB 1 ATOM 8576 N N . LEU C 1 315 ? 3.181 -210.679 37.750 1.00 20.55 ? 386 LEU E N 1 ATOM 8577 C CA . LEU C 1 315 ? 4.051 -210.151 36.704 1.00 19.10 ? 386 LEU E CA 1 ATOM 8578 C C . LEU C 1 315 ? 5.332 -210.969 36.595 1.00 18.18 ? 386 LEU E C 1 ATOM 8579 O O . LEU C 1 315 ? 5.962 -211.286 37.606 1.00 23.36 ? 386 LEU E O 1 ATOM 8580 C CB . LEU C 1 315 ? 4.404 -208.689 36.987 1.00 17.30 ? 386 LEU E CB 1 ATOM 8581 C CG . LEU C 1 315 ? 3.238 -207.710 37.138 1.00 21.20 ? 386 LEU E CG 1 ATOM 8582 C CD1 . LEU C 1 315 ? 3.683 -206.471 37.895 1.00 30.02 ? 386 LEU E CD1 1 ATOM 8583 C CD2 . LEU C 1 315 ? 2.683 -207.328 35.778 1.00 30.64 ? 386 LEU E CD2 1 ATOM 8584 N N . SER C 1 316 ? 5.722 -211.289 35.364 1.00 19.18 ? 387 SER E N 1 ATOM 8585 C CA . SER C 1 316 ? 6.912 -212.097 35.113 1.00 18.33 ? 387 SER E CA 1 ATOM 8586 C C . SER C 1 316 ? 7.602 -211.700 33.814 1.00 18.94 ? 387 SER E C 1 ATOM 8587 O O . SER C 1 316 ? 6.966 -211.181 32.896 1.00 20.84 ? 387 SER E O 1 ATOM 8588 C CB . SER C 1 316 ? 6.543 -213.582 35.063 1.00 23.94 ? 387 SER E CB 1 ATOM 8589 O OG . SER C 1 316 ? 7.643 -214.363 34.636 1.00 25.00 ? 387 SER E OG 1 ATOM 8590 N N . ASP C 1 317 ? 8.907 -211.949 33.748 1.00 19.09 ? 388 ASP E N 1 ATOM 8591 C CA . ASP C 1 317 ? 9.674 -211.751 32.521 1.00 21.98 ? 388 ASP E CA 1 ATOM 8592 C C . ASP C 1 317 ? 9.864 -213.075 31.788 1.00 29.23 ? 388 ASP E C 1 ATOM 8593 O O . ASP C 1 317 ? 10.647 -213.166 30.841 1.00 25.14 ? 388 ASP E O 1 ATOM 8594 C CB . ASP C 1 317 ? 11.033 -211.119 32.831 1.00 20.97 ? 388 ASP E CB 1 ATOM 8595 C CG . ASP C 1 317 ? 11.911 -212.011 33.688 1.00 35.19 ? 388 ASP E CG 1 ATOM 8596 O OD1 . ASP C 1 317 ? 11.377 -212.952 34.313 1.00 48.54 ? 388 ASP E OD1 1 ATOM 8597 O OD2 . ASP C 1 317 ? 13.135 -211.767 33.743 1.00 39.52 ? 388 ASP E OD2 1 ATOM 8598 N N . GLN C 1 318 ? 9.139 -214.097 32.234 1.00 30.04 ? 389 GLN E N 1 ATOM 8599 C CA . GLN C 1 318 ? 9.188 -215.412 31.607 1.00 36.82 ? 389 GLN E CA 1 ATOM 8600 C C . GLN C 1 318 ? 8.199 -215.493 30.456 1.00 20.95 ? 389 GLN E C 1 ATOM 8601 O O . GLN C 1 318 ? 6.990 -215.368 30.654 1.00 25.05 ? 389 GLN E O 1 ATOM 8602 C CB . GLN C 1 318 ? 8.884 -216.510 32.630 1.00 34.95 ? 389 GLN E CB 1 ATOM 8603 C CG . GLN C 1 318 ? 9.928 -216.638 33.726 1.00 37.88 ? 389 GLN E CG 1 ATOM 8604 C CD . GLN C 1 318 ? 11.239 -217.200 33.213 1.00 55.97 ? 389 GLN E CD 1 ATOM 8605 O OE1 . GLN C 1 318 ? 12.276 -216.540 33.267 1.00 57.74 ? 389 GLN E OE1 1 ATOM 8606 N NE2 . GLN C 1 318 ? 11.197 -218.430 32.712 1.00 69.73 ? 389 GLN E NE2 1 ATOM 8607 N N . VAL C 1 319 ? 8.718 -215.695 29.252 1.00 27.68 ? 390 VAL E N 1 ATOM 8608 C CA . VAL C 1 319 ? 7.867 -215.875 28.085 1.00 27.06 ? 390 VAL E CA 1 ATOM 8609 C C . VAL C 1 319 ? 6.958 -217.081 28.305 1.00 25.36 ? 390 VAL E C 1 ATOM 8610 O O . VAL C 1 319 ? 7.444 -218.177 28.579 1.00 31.37 ? 390 VAL E O 1 ATOM 8611 C CB . VAL C 1 319 ? 8.692 -216.078 26.807 1.00 29.15 ? 390 VAL E CB 1 ATOM 8612 C CG1 . VAL C 1 319 ? 7.777 -216.318 25.606 1.00 22.40 ? 390 VAL E CG1 1 ATOM 8613 C CG2 . VAL C 1 319 ? 9.589 -214.875 26.565 1.00 30.56 ? 390 VAL E CG2 1 ATOM 8614 N N . PRO C 1 320 ? 5.635 -216.888 28.196 1.00 25.82 ? 391 PRO E N 1 ATOM 8615 C CA . PRO C 1 320 ? 4.747 -218.035 28.407 1.00 32.39 ? 391 PRO E CA 1 ATOM 8616 C C . PRO C 1 320 ? 4.821 -219.046 27.268 1.00 39.26 ? 391 PRO E C 1 ATOM 8617 O O . PRO C 1 320 ? 4.826 -218.643 26.104 1.00 33.71 ? 391 PRO E O 1 ATOM 8618 C CB . PRO C 1 320 ? 3.359 -217.396 28.475 1.00 31.15 ? 391 PRO E CB 1 ATOM 8619 C CG . PRO C 1 320 ? 3.482 -216.139 27.686 1.00 23.29 ? 391 PRO E CG 1 ATOM 8620 C CD . PRO C 1 320 ? 4.886 -215.654 27.896 1.00 28.43 ? 391 PRO E CD 1 ATOM 8621 N N . ASP C 1 321 ? 4.891 -220.334 27.599 1.00 38.32 ? 392 ASP E N 1 ATOM 8622 C CA . ASP C 1 321 ? 4.792 -221.386 26.592 1.00 41.36 ? 392 ASP E CA 1 ATOM 8623 C C . ASP C 1 321 ? 3.652 -222.339 26.934 1.00 34.91 ? 392 ASP E C 1 ATOM 8624 O O . ASP C 1 321 ? 3.441 -223.338 26.244 1.00 42.79 ? 392 ASP E O 1 ATOM 8625 C CB . ASP C 1 321 ? 6.114 -222.151 26.453 1.00 37.10 ? 392 ASP E CB 1 ATOM 8626 C CG . ASP C 1 321 ? 6.595 -222.749 27.762 1.00 33.68 ? 392 ASP E CG 1 ATOM 8627 O OD1 . ASP C 1 321 ? 5.766 -222.995 28.662 1.00 43.44 ? 392 ASP E OD1 1 ATOM 8628 O OD2 . ASP C 1 321 ? 7.815 -222.985 27.886 1.00 41.38 ? 392 ASP E OD2 1 ATOM 8629 N N . CYS C 1 322 ? 2.924 -222.037 28.006 1.00 30.91 ? 393 CYS E N 1 ATOM 8630 C CA . CYS C 1 322 ? 1.676 -222.741 28.268 1.00 28.31 ? 393 CYS E CA 1 ATOM 8631 C C . CYS C 1 322 ? 0.690 -221.889 29.055 1.00 30.77 ? 393 CYS E C 1 ATOM 8632 O O . CYS C 1 322 ? 1.027 -220.798 29.518 1.00 35.50 ? 393 CYS E O 1 ATOM 8633 C CB . CYS C 1 322 ? 1.953 -224.046 29.014 1.00 41.62 ? 393 CYS E CB 1 ATOM 8634 S SG . CYS C 1 322 ? 2.788 -223.823 30.592 1.00 44.44 ? 393 CYS E SG 1 ATOM 8635 N N . LEU C 1 323 ? -0.530 -222.399 29.191 1.00 25.30 ? 394 LEU E N 1 ATOM 8636 C CA . LEU C 1 323 ? -1.594 -221.705 29.907 1.00 29.03 ? 394 LEU E CA 1 ATOM 8637 C C . LEU C 1 323 ? -2.182 -222.584 31.004 1.00 33.10 ? 394 LEU E C 1 ATOM 8638 O O . LEU C 1 323 ? -2.169 -223.810 30.898 1.00 28.23 ? 394 LEU E O 1 ATOM 8639 C CB . LEU C 1 323 ? -2.705 -221.288 28.940 1.00 32.35 ? 394 LEU E CB 1 ATOM 8640 C CG . LEU C 1 323 ? -2.289 -220.440 27.736 1.00 35.19 ? 394 LEU E CG 1 ATOM 8641 C CD1 . LEU C 1 323 ? -3.451 -220.308 26.768 1.00 28.72 ? 394 LEU E CD1 1 ATOM 8642 C CD2 . LEU C 1 323 ? -1.807 -219.074 28.185 1.00 32.13 ? 394 LEU E CD2 1 ATOM 8643 N N . VAL C 1 324 ? -2.689 -221.947 32.056 1.00 23.79 ? 395 VAL E N 1 ATOM 8644 C CA . VAL C 1 324 ? -3.476 -222.636 33.074 1.00 27.11 ? 395 VAL E CA 1 ATOM 8645 C C . VAL C 1 324 ? -4.872 -222.029 33.096 1.00 31.65 ? 395 VAL E C 1 ATOM 8646 O O . VAL C 1 324 ? -5.027 -220.830 33.306 1.00 37.11 ? 395 VAL E O 1 ATOM 8647 C CB . VAL C 1 324 ? -2.829 -222.531 34.472 1.00 25.33 ? 395 VAL E CB 1 ATOM 8648 C CG1 . VAL C 1 324 ? -3.754 -223.098 35.543 1.00 29.92 ? 395 VAL E CG1 1 ATOM 8649 C CG2 . VAL C 1 324 ? -1.492 -223.257 34.492 1.00 32.51 ? 395 VAL E CG2 1 ATOM 8650 N N . SER C 1 325 ? -5.890 -222.855 32.881 1.00 28.66 ? 396 SER E N 1 ATOM 8651 C CA . SER C 1 325 ? -7.255 -222.355 32.805 1.00 30.27 ? 396 SER E CA 1 ATOM 8652 C C . SER C 1 325 ? -7.725 -221.838 34.165 1.00 34.54 ? 396 SER E C 1 ATOM 8653 O O . SER C 1 325 ? -7.455 -222.447 35.201 1.00 38.69 ? 396 SER E O 1 ATOM 8654 C CB . SER C 1 325 ? -8.198 -223.446 32.296 1.00 40.82 ? 396 SER E CB 1 ATOM 8655 O OG . SER C 1 325 ? -8.300 -224.508 33.227 1.00 59.24 ? 396 SER E OG 1 ATOM 8656 N N . ASP C 1 326 ? -8.423 -220.706 34.146 1.00 33.91 ? 397 ASP E N 1 ATOM 8657 C CA . ASP C 1 326 ? -8.921 -220.061 35.359 1.00 32.59 ? 397 ASP E CA 1 ATOM 8658 C C . ASP C 1 326 ? -9.931 -218.993 34.951 1.00 40.96 ? 397 ASP E C 1 ATOM 8659 O O . ASP C 1 326 ? -9.559 -217.943 34.429 1.00 46.54 ? 397 ASP E O 1 ATOM 8660 C CB . ASP C 1 326 ? -7.768 -219.454 36.169 1.00 35.94 ? 397 ASP E CB 1 ATOM 8661 C CG . ASP C 1 326 ? -8.234 -218.782 37.453 1.00 39.58 ? 397 ASP E CG 1 ATOM 8662 O OD1 . ASP C 1 326 ? -9.406 -218.968 37.845 1.00 47.63 ? 397 ASP E OD1 1 ATOM 8663 O OD2 . ASP C 1 326 ? -7.416 -218.074 38.081 1.00 42.09 ? 397 ASP E OD2 1 ATOM 8664 N N . SER C 1 327 ? -11.207 -219.271 35.196 1.00 38.79 ? 398 SER E N 1 ATOM 8665 C CA . SER C 1 327 ? -12.301 -218.493 34.619 1.00 53.88 ? 398 SER E CA 1 ATOM 8666 C C . SER C 1 327 ? -12.304 -217.018 35.026 1.00 44.65 ? 398 SER E C 1 ATOM 8667 O O . SER C 1 327 ? -12.772 -216.168 34.271 1.00 45.19 ? 398 SER E O 1 ATOM 8668 C CB . SER C 1 327 ? -13.640 -219.126 35.003 1.00 45.73 ? 398 SER E CB 1 ATOM 8669 O OG . SER C 1 327 ? -13.883 -219.002 36.394 1.00 51.94 ? 398 SER E OG 1 ATOM 8670 N N . ALA C 1 328 ? -11.783 -216.715 36.211 1.00 42.85 ? 399 ALA E N 1 ATOM 8671 C CA . ALA C 1 328 ? -11.794 -215.345 36.714 1.00 42.02 ? 399 ALA E CA 1 ATOM 8672 C C . ALA C 1 328 ? -10.512 -214.594 36.362 1.00 36.08 ? 399 ALA E C 1 ATOM 8673 O O . ALA C 1 328 ? -10.395 -213.399 36.634 1.00 33.92 ? 399 ALA E O 1 ATOM 8674 C CB . ALA C 1 328 ? -12.002 -215.342 38.216 1.00 41.81 ? 399 ALA E CB 1 ATOM 8675 N N . ALA C 1 329 ? -9.560 -215.293 35.753 1.00 25.10 ? 400 ALA E N 1 ATOM 8676 C CA . ALA C 1 329 ? -8.253 -214.714 35.467 1.00 30.10 ? 400 ALA E CA 1 ATOM 8677 C C . ALA C 1 329 ? -8.204 -214.059 34.096 1.00 37.69 ? 400 ALA E C 1 ATOM 8678 O O . ALA C 1 329 ? -8.962 -214.428 33.197 1.00 29.69 ? 400 ALA E O 1 ATOM 8679 C CB . ALA C 1 329 ? -7.176 -215.781 35.563 1.00 24.34 ? 400 ALA E CB 1 ATOM 8680 N N . VAL C 1 330 ? -7.306 -213.088 33.939 1.00 24.64 ? 401 VAL E N 1 ATOM 8681 C CA . VAL C 1 330 ? -7.057 -212.501 32.620 1.00 25.44 ? 401 VAL E CA 1 ATOM 8682 C C . VAL C 1 330 ? -5.571 -212.218 32.441 1.00 18.68 ? 401 VAL E C 1 ATOM 8683 O O . VAL C 1 330 ? -4.950 -211.559 33.274 1.00 24.14 ? 401 VAL E O 1 ATOM 8684 C CB . VAL C 1 330 ? -7.853 -211.193 32.394 1.00 27.23 ? 401 VAL E CB 1 ATOM 8685 C CG1 . VAL C 1 330 ? -7.619 -210.662 30.980 1.00 26.10 ? 401 VAL E CG1 1 ATOM 8686 C CG2 . VAL C 1 330 ? -9.342 -211.418 32.616 1.00 27.80 ? 401 VAL E CG2 1 ATOM 8687 N N . SER C 1 331 ? -5.012 -212.720 31.343 1.00 18.58 ? 402 SER E N 1 ATOM 8688 C CA . SER C 1 331 ? -3.594 -212.555 31.045 1.00 23.56 ? 402 SER E CA 1 ATOM 8689 C C . SER C 1 331 ? -3.330 -211.379 30.107 1.00 30.46 ? 402 SER E C 1 ATOM 8690 O O . SER C 1 331 ? -3.961 -211.249 29.057 1.00 22.89 ? 402 SER E O 1 ATOM 8691 C CB . SER C 1 331 ? -3.037 -213.840 30.437 1.00 23.90 ? 402 SER E CB 1 ATOM 8692 O OG . SER C 1 331 ? -2.945 -214.865 31.412 1.00 22.79 ? 402 SER E OG 1 ATOM 8693 N N . TYR C 1 332 ? -2.384 -210.533 30.505 1.00 32.74 ? 403 TYR E N 1 ATOM 8694 C CA . TYR C 1 332 ? -2.003 -209.351 29.747 1.00 17.57 ? 403 TYR E CA 1 ATOM 8695 C C . TYR C 1 332 ? -0.523 -209.335 29.394 1.00 22.97 ? 403 TYR E C 1 ATOM 8696 O O . TYR C 1 332 ? 0.305 -209.961 30.070 1.00 23.96 ? 403 TYR E O 1 ATOM 8697 C CB . TYR C 1 332 ? -2.319 -208.081 30.541 1.00 17.55 ? 403 TYR E CB 1 ATOM 8698 C CG . TYR C 1 332 ? -3.749 -207.930 30.982 1.00 16.34 ? 403 TYR E CG 1 ATOM 8699 C CD1 . TYR C 1 332 ? -4.748 -207.600 30.077 1.00 18.31 ? 403 TYR E CD1 1 ATOM 8700 C CD2 . TYR C 1 332 ? -4.097 -208.084 32.317 1.00 18.73 ? 403 TYR E CD2 1 ATOM 8701 C CE1 . TYR C 1 332 ? -6.055 -207.448 30.484 1.00 18.59 ? 403 TYR E CE1 1 ATOM 8702 C CE2 . TYR C 1 332 ? -5.401 -207.934 32.734 1.00 18.87 ? 403 TYR E CE2 1 ATOM 8703 C CZ . TYR C 1 332 ? -6.376 -207.616 31.814 1.00 16.14 ? 403 TYR E CZ 1 ATOM 8704 O OH . TYR C 1 332 ? -7.679 -207.462 32.223 1.00 22.19 ? 403 TYR E OH 1 ATOM 8705 N N . THR C 1 333 ? -0.206 -208.590 28.338 1.00 19.02 ? 404 THR E N 1 ATOM 8706 C CA . THR C 1 333 ? 1.171 -208.274 27.986 1.00 17.18 ? 404 THR E CA 1 ATOM 8707 C C . THR C 1 333 ? 1.315 -206.764 27.847 1.00 23.64 ? 404 THR E C 1 ATOM 8708 O O . THR C 1 333 ? 0.322 -206.050 27.706 1.00 19.55 ? 404 THR E O 1 ATOM 8709 C CB . THR C 1 333 ? 1.607 -208.953 26.673 1.00 23.13 ? 404 THR E CB 1 ATOM 8710 O OG1 . THR C 1 333 ? 0.989 -208.297 25.557 1.00 26.73 ? 404 THR E OG1 1 ATOM 8711 C CG2 . THR C 1 333 ? 1.233 -210.432 26.680 1.00 27.73 ? 404 THR E CG2 1 ATOM 8712 N N . ALA C 1 334 ? 2.553 -206.285 27.888 1.00 18.24 ? 405 ALA E N 1 ATOM 8713 C CA . ALA C 1 334 ? 2.829 -204.858 27.787 1.00 24.04 ? 405 ALA E CA 1 ATOM 8714 C C . ALA C 1 334 ? 2.394 -204.287 26.435 1.00 29.46 ? 405 ALA E C 1 ATOM 8715 O O . ALA C 1 334 ? 2.153 -203.087 26.313 1.00 21.21 ? 405 ALA E O 1 ATOM 8716 C CB . ALA C 1 334 ? 4.311 -204.597 28.014 1.00 16.68 ? 405 ALA E CB 1 ATOM 8717 N N . ALA C 1 335 ? 2.288 -205.152 25.429 1.00 22.77 ? 406 ALA E N 1 ATOM 8718 C CA . ALA C 1 335 ? 1.988 -204.723 24.065 1.00 22.10 ? 406 ALA E CA 1 ATOM 8719 C C . ALA C 1 335 ? 0.495 -204.725 23.757 1.00 21.20 ? 406 ALA E C 1 ATOM 8720 O O . ALA C 1 335 ? 0.028 -203.958 22.914 1.00 20.10 ? 406 ALA E O 1 ATOM 8721 C CB . ALA C 1 335 ? 2.712 -205.614 23.071 1.00 22.16 ? 406 ALA E CB 1 ATOM 8722 N N . GLY C 1 336 ? -0.250 -205.589 24.437 1.00 21.25 ? 407 GLY E N 1 ATOM 8723 C CA . GLY C 1 336 ? -1.638 -205.832 24.088 1.00 12.22 ? 407 GLY E CA 1 ATOM 8724 C C . GLY C 1 336 ? -2.640 -204.875 24.697 1.00 18.59 ? 407 GLY E C 1 ATOM 8725 O O . GLY C 1 336 ? -2.301 -204.021 25.517 1.00 18.13 ? 407 GLY E O 1 ATOM 8726 N N . SER C 1 337 ? -3.892 -205.033 24.281 1.00 17.70 ? 408 SER E N 1 ATOM 8727 C CA . SER C 1 337 ? -4.985 -204.189 24.743 1.00 21.12 ? 408 SER E CA 1 ATOM 8728 C C . SER C 1 337 ? -5.612 -204.721 26.021 1.00 20.19 ? 408 SER E C 1 ATOM 8729 O O . SER C 1 337 ? -5.361 -205.857 26.430 1.00 21.59 ? 408 SER E O 1 ATOM 8730 C CB . SER C 1 337 ? -6.063 -204.085 23.665 1.00 22.18 ? 408 SER E CB 1 ATOM 8731 O OG . SER C 1 337 ? -6.678 -205.344 23.459 1.00 32.12 ? 408 SER E OG 1 ATOM 8732 N N . LEU C 1 338 ? -6.446 -203.890 26.634 1.00 16.97 ? 409 LEU E N 1 ATOM 8733 C CA . LEU C 1 338 ? -7.201 -204.283 27.810 1.00 24.26 ? 409 LEU E CA 1 ATOM 8734 C C . LEU C 1 338 ? -8.312 -205.246 27.423 1.00 33.39 ? 409 LEU E C 1 ATOM 8735 O O . LEU C 1 338 ? -8.618 -206.187 28.156 1.00 26.59 ? 409 LEU E O 1 ATOM 8736 C CB . LEU C 1 338 ? -7.792 -203.054 28.504 1.00 27.02 ? 409 LEU E CB 1 ATOM 8737 C CG . LEU C 1 338 ? -8.749 -203.329 29.668 1.00 28.04 ? 409 LEU E CG 1 ATOM 8738 C CD1 . LEU C 1 338 ? -8.038 -204.082 30.777 1.00 26.67 ? 409 LEU E CD1 1 ATOM 8739 C CD2 . LEU C 1 338 ? -9.343 -202.033 30.190 1.00 36.82 ? 409 LEU E CD2 1 ATOM 8740 N N . SER C 1 339 ? -8.916 -205.001 26.265 1.00 32.26 ? 410 SER E N 1 ATOM 8741 C CA . SER C 1 339 ? -10.059 -205.784 25.818 1.00 33.98 ? 410 SER E CA 1 ATOM 8742 C C . SER C 1 339 ? -9.644 -207.177 25.359 1.00 21.89 ? 410 SER E C 1 ATOM 8743 O O . SER C 1 339 ? -8.561 -207.366 24.802 1.00 22.97 ? 410 SER E O 1 ATOM 8744 C CB . SER C 1 339 ? -10.786 -205.063 24.682 1.00 40.83 ? 410 SER E CB 1 ATOM 8745 O OG . SER C 1 339 ? -11.976 -205.747 24.330 1.00 41.54 ? 410 SER E OG 1 ATOM 8746 N N . GLU C 1 340 ? -10.514 -208.137 25.619 1.00 31.88 ? 411 GLU E N 1 ATOM 8747 C CA . GLU C 1 340 ? -10.304 -209.503 25.195 1.00 38.59 ? 411 GLU E CA 1 ATOM 8748 C C . GLU C 1 340 ? -10.872 -209.710 23.796 1.00 37.84 ? 411 GLU E C 1 ATOM 8749 O O . GLU C 1 340 ? -10.506 -210.637 23.116 1.00 44.10 ? 411 GLU E O 1 ATOM 8750 C CB . GLU C 1 340 ? -10.939 -210.473 26.180 1.00 40.49 ? 411 GLU E CB 1 ATOM 8751 C CG . GLU C 1 340 ? -10.469 -210.306 27.615 1.00 58.60 ? 411 GLU E CG 1 ATOM 8752 C CD . GLU C 1 340 ? -11.422 -209.477 28.450 1.00 90.98 ? 411 GLU E CD 1 ATOM 8753 O OE1 . GLU C 1 340 ? -11.241 -209.394 29.679 1.00 43.62 ? 411 GLU E OE1 1 ATOM 8754 O OE2 . GLU C 1 340 ? -12.372 -208.915 27.864 1.00 78.92 ? 411 GLU E OE2 1 ATOM 8755 N N . GLU C 1 341 ? -11.781 -208.837 23.388 1.00 41.40 ? 412 GLU E N 1 ATOM 8756 C CA . GLU C 1 341 ? -12.424 -208.915 22.077 1.00 42.24 ? 412 GLU E CA 1 ATOM 8757 C C . GLU C 1 341 ? -11.590 -208.352 20.941 1.00 45.59 ? 412 GLU E C 1 ATOM 8758 O O . GLU C 1 341 ? -10.871 -207.402 21.111 1.00 43.67 ? 412 GLU E O 1 ATOM 8759 C CB . GLU C 1 341 ? -13.767 -208.194 22.086 1.00 53.34 ? 412 GLU E CB 1 ATOM 8760 C CG . GLU C 1 341 ? -14.813 -208.790 23.001 1.00 71.50 ? 412 GLU E CG 1 ATOM 8761 C CD . GLU C 1 341 ? -16.176 -208.159 22.799 1.00 108.72 ? 412 GLU E CD 1 ATOM 8762 O OE1 . GLU C 1 341 ? -16.719 -208.274 21.679 1.00 102.85 ? 412 GLU E OE1 1 ATOM 8763 O OE2 . GLU C 1 341 ? -16.708 -207.555 23.754 1.00 118.70 ? 412 GLU E OE2 1 ATOM 8764 N N . THR C 1 342 ? -11.715 -208.941 19.774 1.00 39.81 ? 413 THR E N 1 ATOM 8765 C CA . THR C 1 342 ? -10.986 -208.467 18.628 1.00 44.26 ? 413 THR E CA 1 ATOM 8766 C C . THR C 1 342 ? -11.818 -207.393 17.966 1.00 31.84 ? 413 THR E C 1 ATOM 8767 O O . THR C 1 342 ? -12.952 -207.624 17.643 1.00 41.56 ? 413 THR E O 1 ATOM 8768 C CB . THR C 1 342 ? -10.769 -209.601 17.628 1.00 37.90 ? 413 THR E CB 1 ATOM 8769 O OG1 . THR C 1 342 ? -9.968 -210.613 18.228 1.00 47.99 ? 413 THR E OG1 1 ATOM 8770 C CG2 . THR C 1 342 ? -10.085 -209.096 16.396 1.00 39.18 ? 413 THR E CG2 1 ATOM 8771 N N . PRO C 1 343 ? -11.257 -206.212 17.775 1.00 33.51 ? 414 PRO E N 1 ATOM 8772 C CA . PRO C 1 343 ? -12.008 -205.125 17.136 1.00 30.63 ? 414 PRO E CA 1 ATOM 8773 C C . PRO C 1 343 ? -12.029 -205.247 15.614 1.00 33.19 ? 414 PRO E C 1 ATOM 8774 O O . PRO C 1 343 ? -11.186 -205.939 15.042 1.00 29.80 ? 414 PRO E O 1 ATOM 8775 C CB . PRO C 1 343 ? -11.246 -203.876 17.574 1.00 38.74 ? 414 PRO E CB 1 ATOM 8776 C CG . PRO C 1 343 ? -9.842 -204.342 17.704 1.00 38.35 ? 414 PRO E CG 1 ATOM 8777 C CD . PRO C 1 343 ? -9.920 -205.765 18.207 1.00 37.32 ? 414 PRO E CD 1 ATOM 8778 N N . ASN C 1 344 ? -12.979 -204.574 14.972 1.00 36.11 ? 415 ASN E N 1 ATOM 8779 C CA . ASN C 1 344 ? -13.157 -204.687 13.528 1.00 35.61 ? 415 ASN E CA 1 ATOM 8780 C C . ASN C 1 344 ? -11.974 -204.154 12.729 1.00 34.00 ? 415 ASN E C 1 ATOM 8781 O O . ASN C 1 344 ? -11.687 -204.649 11.640 1.00 41.43 ? 415 ASN E O 1 ATOM 8782 C CB . ASN C 1 344 ? -14.428 -203.951 13.094 1.00 49.28 ? 415 ASN E CB 1 ATOM 8783 C CG . ASN C 1 344 ? -15.692 -204.604 13.623 1.00 60.41 ? 415 ASN E CG 1 ATOM 8784 O OD1 . ASN C 1 344 ? -16.538 -203.945 14.229 1.00 71.04 ? 415 ASN E OD1 1 ATOM 8785 N ND2 . ASN C 1 344 ? -15.826 -205.906 13.396 1.00 53.73 ? 415 ASN E ND2 1 ATOM 8786 N N . PHE C 1 345 ? -11.281 -203.153 13.265 1.00 32.40 ? 416 PHE E N 1 ATOM 8787 C CA . PHE C 1 345 ? -10.257 -202.463 12.488 1.00 31.62 ? 416 PHE E CA 1 ATOM 8788 C C . PHE C 1 345 ? -8.939 -203.238 12.390 1.00 39.96 ? 416 PHE E C 1 ATOM 8789 O O . PHE C 1 345 ? -7.964 -202.722 11.841 1.00 36.77 ? 416 PHE E O 1 ATOM 8790 C CB . PHE C 1 345 ? -10.003 -201.063 13.062 1.00 30.00 ? 416 PHE E CB 1 ATOM 8791 C CG . PHE C 1 345 ? -9.420 -201.057 14.445 1.00 28.23 ? 416 PHE E CG 1 ATOM 8792 C CD1 . PHE C 1 345 ? -8.054 -201.162 14.636 1.00 30.21 ? 416 PHE E CD1 1 ATOM 8793 C CD2 . PHE C 1 345 ? -10.238 -200.916 15.553 1.00 39.07 ? 416 PHE E CD2 1 ATOM 8794 C CE1 . PHE C 1 345 ? -7.514 -201.147 15.906 1.00 33.42 ? 416 PHE E CE1 1 ATOM 8795 C CE2 . PHE C 1 345 ? -9.704 -200.898 16.827 1.00 30.65 ? 416 PHE E CE2 1 ATOM 8796 C CZ . PHE C 1 345 ? -8.339 -201.015 17.003 1.00 19.55 ? 416 PHE E CZ 1 ATOM 8797 N N . ILE C 1 346 ? -8.908 -204.467 12.909 1.00 33.18 ? 417 ILE E N 1 ATOM 8798 C CA . ILE C 1 346 ? -7.790 -205.375 12.643 1.00 28.25 ? 417 ILE E CA 1 ATOM 8799 C C . ILE C 1 346 ? -8.285 -206.692 12.036 1.00 33.11 ? 417 ILE E C 1 ATOM 8800 O O . ILE C 1 346 ? -7.544 -207.673 11.971 1.00 35.09 ? 417 ILE E O 1 ATOM 8801 C CB . ILE C 1 346 ? -6.954 -205.668 13.917 1.00 29.23 ? 417 ILE E CB 1 ATOM 8802 C CG1 . ILE C 1 346 ? -7.772 -206.411 14.978 1.00 32.82 ? 417 ILE E CG1 1 ATOM 8803 C CG2 . ILE C 1 346 ? -6.390 -204.370 14.490 1.00 36.46 ? 417 ILE E CG2 1 ATOM 8804 C CD1 . ILE C 1 346 ? -6.904 -207.032 16.061 1.00 32.34 ? 417 ILE E CD1 1 ATOM 8805 N N . ILE C 1 347 ? -9.537 -206.699 11.587 1.00 39.45 ? 418 ILE E N 1 ATOM 8806 C CA . ILE C 1 347 ? -10.109 -207.844 10.881 1.00 43.12 ? 418 ILE E CA 1 ATOM 8807 C C . ILE C 1 347 ? -10.162 -207.550 9.378 1.00 41.12 ? 418 ILE E C 1 ATOM 8808 O O . ILE C 1 347 ? -10.817 -206.595 8.964 1.00 38.36 ? 418 ILE E O 1 ATOM 8809 C CB . ILE C 1 347 ? -11.523 -208.172 11.395 1.00 38.97 ? 418 ILE E CB 1 ATOM 8810 C CG1 . ILE C 1 347 ? -11.462 -208.602 12.862 1.00 40.16 ? 418 ILE E CG1 1 ATOM 8811 C CG2 . ILE C 1 347 ? -12.156 -209.282 10.559 1.00 47.64 ? 418 ILE E CG2 1 ATOM 8812 C CD1 . ILE C 1 347 ? -12.815 -208.700 13.539 1.00 46.82 ? 418 ILE E CD1 1 ATOM 8813 N N . PRO C 1 348 ? -9.470 -208.359 8.554 1.00 40.38 ? 419 PRO E N 1 ATOM 8814 C CA . PRO C 1 348 ? -9.535 -208.133 7.102 1.00 46.23 ? 419 PRO E CA 1 ATOM 8815 C C . PRO C 1 348 ? -10.923 -208.396 6.517 1.00 59.58 ? 419 PRO E C 1 ATOM 8816 O O . PRO C 1 348 ? -11.721 -209.112 7.121 1.00 67.49 ? 419 PRO E O 1 ATOM 8817 C CB . PRO C 1 348 ? -8.515 -209.132 6.540 1.00 37.58 ? 419 PRO E CB 1 ATOM 8818 C CG . PRO C 1 348 ? -7.624 -209.470 7.687 1.00 42.17 ? 419 PRO E CG 1 ATOM 8819 C CD . PRO C 1 348 ? -8.493 -209.408 8.898 1.00 40.56 ? 419 PRO E CD 1 ATOM 8820 N N . SER C 1 349 ? -11.198 -207.820 5.350 1.00 83.95 ? 420 SER E N 1 ATOM 8821 C CA . SER C 1 349 ? -12.487 -207.993 4.685 1.00 100.20 ? 420 SER E CA 1 ATOM 8822 C C . SER C 1 349 ? -12.734 -209.448 4.299 1.00 95.60 ? 420 SER E C 1 ATOM 8823 O O . SER C 1 349 ? -13.880 -209.891 4.215 1.00 81.02 ? 420 SER E O 1 ATOM 8824 C CB . SER C 1 349 ? -12.563 -207.109 3.440 1.00 63.69 ? 420 SER E CB 1 ATOM 8825 O OG . SER C 1 349 ? -12.380 -205.745 3.776 1.00 86.94 ? 420 SER E OG 1 ATOM 8826 N N . ASN C 1 350 ? -11.655 -210.186 4.061 1.00 88.18 ? 421 ASN E N 1 ATOM 8827 C CA . ASN C 1 350 ? -11.754 -211.584 3.662 1.00 93.51 ? 421 ASN E CA 1 ATOM 8828 C C . ASN C 1 350 ? -12.312 -212.447 4.791 1.00 94.38 ? 421 ASN E C 1 ATOM 8829 O O . ASN C 1 350 ? -12.066 -213.652 4.850 1.00 96.58 ? 421 ASN E O 1 ATOM 8830 C CB . ASN C 1 350 ? -10.383 -212.107 3.226 1.00 93.90 ? 421 ASN E CB 1 ATOM 8831 C CG . ASN C 1 350 ? -10.466 -213.053 2.043 1.00 106.78 ? 421 ASN E CG 1 ATOM 8832 O OD1 . ASN C 1 350 ? -11.476 -213.728 1.838 1.00 97.78 ? 421 ASN E OD1 1 ATOM 8833 N ND2 . ASN C 1 350 ? -9.398 -213.104 1.254 1.00 99.43 ? 421 ASN E ND2 1 ATOM 8834 N N . PRO C 1 356 ? -8.790 -216.949 12.912 1.00 92.29 ? 427 PRO E N 1 ATOM 8835 C CA . PRO C 1 356 ? -9.085 -216.252 14.170 1.00 100.03 ? 427 PRO E CA 1 ATOM 8836 C C . PRO C 1 356 ? -8.347 -216.886 15.353 1.00 100.34 ? 427 PRO E C 1 ATOM 8837 O O . PRO C 1 356 ? -8.755 -217.932 15.851 1.00 108.56 ? 427 PRO E O 1 ATOM 8838 C CB . PRO C 1 356 ? -10.608 -216.398 14.309 1.00 89.14 ? 427 PRO E CB 1 ATOM 8839 C CG . PRO C 1 356 ? -11.099 -216.723 12.927 1.00 89.27 ? 427 PRO E CG 1 ATOM 8840 C CD . PRO C 1 356 ? -10.002 -217.511 12.293 1.00 86.75 ? 427 PRO E CD 1 ATOM 8841 N N . THR C 1 357 ? -7.277 -216.239 15.803 1.00 97.66 ? 428 THR E N 1 ATOM 8842 C CA . THR C 1 357 ? -6.334 -216.851 16.737 1.00 99.79 ? 428 THR E CA 1 ATOM 8843 C C . THR C 1 357 ? -6.914 -217.276 18.097 1.00 96.15 ? 428 THR E C 1 ATOM 8844 O O . THR C 1 357 ? -6.627 -218.380 18.561 1.00 75.57 ? 428 THR E O 1 ATOM 8845 C CB . THR C 1 357 ? -5.148 -215.903 16.999 1.00 81.86 ? 428 THR E CB 1 ATOM 8846 O OG1 . THR C 1 357 ? -5.622 -214.554 17.089 1.00 85.03 ? 428 THR E OG1 1 ATOM 8847 C CG2 . THR C 1 357 ? -4.133 -215.998 15.867 1.00 67.82 ? 428 THR E CG2 1 ATOM 8848 N N . PRO C 1 358 ? -7.729 -216.421 18.741 1.00 112.18 ? 429 PRO E N 1 ATOM 8849 C CA . PRO C 1 358 ? -8.123 -216.796 20.105 1.00 97.18 ? 429 PRO E CA 1 ATOM 8850 C C . PRO C 1 358 ? -9.139 -217.936 20.151 1.00 101.38 ? 429 PRO E C 1 ATOM 8851 O O . PRO C 1 358 ? -8.976 -218.877 20.928 1.00 80.83 ? 429 PRO E O 1 ATOM 8852 C CB . PRO C 1 358 ? -8.730 -215.504 20.653 1.00 110.73 ? 429 PRO E CB 1 ATOM 8853 C CG . PRO C 1 358 ? -9.305 -214.836 19.454 1.00 112.45 ? 429 PRO E CG 1 ATOM 8854 C CD . PRO C 1 358 ? -8.410 -215.190 18.294 1.00 98.72 ? 429 PRO E CD 1 ATOM 8855 N N . GLU C 1 359 ? -10.169 -217.848 19.316 1.00 130.64 ? 430 GLU E N 1 ATOM 8856 C CA . GLU C 1 359 ? -11.247 -218.828 19.313 1.00 121.53 ? 430 GLU E CA 1 ATOM 8857 C C . GLU C 1 359 ? -10.747 -220.157 18.764 1.00 106.29 ? 430 GLU E C 1 ATOM 8858 O O . GLU C 1 359 ? -11.013 -221.219 19.323 1.00 108.29 ? 430 GLU E O 1 ATOM 8859 C CB . GLU C 1 359 ? -12.436 -218.341 18.470 1.00 119.92 ? 430 GLU E CB 1 ATOM 8860 C CG . GLU C 1 359 ? -12.791 -216.853 18.599 1.00 122.93 ? 430 GLU E CG 1 ATOM 8861 C CD . GLU C 1 359 ? -13.416 -216.495 19.935 1.00 128.51 ? 430 GLU E CD 1 ATOM 8862 O OE1 . GLU C 1 359 ? -13.135 -215.389 20.447 1.00 125.09 ? 430 GLU E OE1 1 ATOM 8863 O OE2 . GLU C 1 359 ? -14.202 -217.307 20.466 1.00 117.17 ? 430 GLU E OE2 1 ATOM 8864 N N . THR C 1 360 ? -10.003 -220.080 17.668 1.00 91.80 ? 431 THR E N 1 ATOM 8865 C CA . THR C 1 360 ? -9.642 -221.257 16.891 1.00 98.02 ? 431 THR E CA 1 ATOM 8866 C C . THR C 1 360 ? -8.742 -222.233 17.651 1.00 86.52 ? 431 THR E C 1 ATOM 8867 O O . THR C 1 360 ? -8.986 -223.439 17.644 1.00 92.16 ? 431 THR E O 1 ATOM 8868 C CB . THR C 1 360 ? -8.937 -220.843 15.585 1.00 94.47 ? 431 THR E CB 1 ATOM 8869 O OG1 . THR C 1 360 ? -9.723 -219.852 14.910 1.00 111.46 ? 431 THR E OG1 1 ATOM 8870 C CG2 . THR C 1 360 ? -8.747 -222.037 14.667 1.00 96.99 ? 431 THR E CG2 1 ATOM 8871 N N . ALA C 1 361 ? -7.711 -221.713 18.309 1.00 66.01 ? 432 ALA E N 1 ATOM 8872 C CA . ALA C 1 361 ? -6.671 -222.564 18.880 1.00 66.97 ? 432 ALA E CA 1 ATOM 8873 C C . ALA C 1 361 ? -7.105 -223.258 20.172 1.00 56.05 ? 432 ALA E C 1 ATOM 8874 O O . ALA C 1 361 ? -6.747 -224.412 20.407 1.00 68.27 ? 432 ALA E O 1 ATOM 8875 C CB . ALA C 1 361 ? -5.414 -221.748 19.126 1.00 51.69 ? 432 ALA E CB 1 ATOM 8876 N N . LEU C 1 362 ? -7.877 -222.561 21.001 1.00 68.91 ? 433 LEU E N 1 ATOM 8877 C CA . LEU C 1 362 ? -8.228 -223.073 22.325 1.00 69.69 ? 433 LEU E CA 1 ATOM 8878 C C . LEU C 1 362 ? -9.600 -223.746 22.361 1.00 71.88 ? 433 LEU E C 1 ATOM 8879 O O . LEU C 1 362 ? -10.091 -224.101 23.433 1.00 55.00 ? 433 LEU E O 1 ATOM 8880 C CB . LEU C 1 362 ? -8.186 -221.940 23.353 1.00 65.85 ? 433 LEU E CB 1 ATOM 8881 C CG . LEU C 1 362 ? -6.930 -221.062 23.337 1.00 48.94 ? 433 LEU E CG 1 ATOM 8882 C CD1 . LEU C 1 362 ? -6.964 -220.074 24.493 1.00 50.27 ? 433 LEU E CD1 1 ATOM 8883 C CD2 . LEU C 1 362 ? -5.656 -221.896 23.383 1.00 48.06 ? 433 LEU E CD2 1 ATOM 8884 N N . GLN C 1 363 ? -10.214 -223.921 21.194 1.00 82.24 ? 434 GLN E N 1 ATOM 8885 C CA . GLN C 1 363 ? -11.498 -224.613 21.104 1.00 86.07 ? 434 GLN E CA 1 ATOM 8886 C C . GLN C 1 363 ? -11.304 -226.115 20.938 1.00 72.59 ? 434 GLN E C 1 ATOM 8887 O O . GLN C 1 363 ? -10.251 -226.572 20.492 1.00 64.65 ? 434 GLN E O 1 ATOM 8888 C CB . GLN C 1 363 ? -12.325 -224.070 19.940 1.00 90.98 ? 434 GLN E CB 1 ATOM 8889 C CG . GLN C 1 363 ? -13.275 -222.948 20.319 1.00 95.84 ? 434 GLN E CG 1 ATOM 8890 C CD . GLN C 1 363 ? -14.009 -222.389 19.118 1.00 119.56 ? 434 GLN E CD 1 ATOM 8891 O OE1 . GLN C 1 363 ? -14.076 -223.028 18.068 1.00 95.79 ? 434 GLN E OE1 1 ATOM 8892 N NE2 . GLN C 1 363 ? -14.560 -221.190 19.263 1.00 125.58 ? 434 GLN E NE2 1 ATOM 8893 N N . CYS C 1 364 ? -12.332 -226.876 21.300 1.00 74.47 ? 435 CYS E N 1 ATOM 8894 C CA . CYS C 1 364 ? -12.308 -228.328 21.165 1.00 89.31 ? 435 CYS E CA 1 ATOM 8895 C C . CYS C 1 364 ? -13.700 -228.903 21.400 1.00 95.86 ? 435 CYS E C 1 ATOM 8896 O O . CYS C 1 364 ? -14.557 -228.249 21.996 1.00 90.90 ? 435 CYS E O 1 ATOM 8897 C CB . CYS C 1 364 ? -11.315 -228.948 22.151 1.00 91.58 ? 435 CYS E CB 1 ATOM 8898 S SG . CYS C 1 364 ? -11.690 -228.604 23.886 1.00 109.16 ? 435 CYS E SG 1 ATOM 8899 N N . THR C 1 365 ? -13.916 -230.125 20.921 1.00 107.16 ? 436 THR E N 1 ATOM 8900 C CA . THR C 1 365 ? -15.142 -230.867 21.202 1.00 94.65 ? 436 THR E CA 1 ATOM 8901 C C . THR C 1 365 ? -14.788 -232.087 22.047 1.00 87.73 ? 436 THR E C 1 ATOM 8902 O O . THR C 1 365 ? -13.817 -232.790 21.765 1.00 78.89 ? 436 THR E O 1 ATOM 8903 C CB . THR C 1 365 ? -15.862 -231.292 19.911 1.00 91.27 ? 436 THR E CB 1 ATOM 8904 O OG1 . THR C 1 365 ? -14.946 -231.978 19.050 1.00 118.33 ? 436 THR E OG1 1 ATOM 8905 C CG2 . THR C 1 365 ? -16.413 -230.070 19.189 1.00 73.29 ? 436 THR E CG2 1 ATOM 8906 N N . ALA C 1 366 ? -15.591 -232.328 23.079 1.00 92.29 ? 437 ALA E N 1 ATOM 8907 C CA . ALA C 1 366 ? -15.233 -233.240 24.164 1.00 107.62 ? 437 ALA E CA 1 ATOM 8908 C C . ALA C 1 366 ? -14.891 -234.665 23.719 1.00 110.26 ? 437 ALA E C 1 ATOM 8909 O O . ALA C 1 366 ? -14.034 -235.310 24.323 1.00 102.99 ? 437 ALA E O 1 ATOM 8910 C CB . ALA C 1 366 ? -16.364 -233.281 25.181 1.00 74.63 ? 437 ALA E CB 1 ATOM 8911 N N . ASP C 1 367 ? -15.552 -235.153 22.673 1.00 117.52 ? 438 ASP E N 1 ATOM 8912 C CA . ASP C 1 367 ? -15.382 -236.544 22.249 1.00 119.81 ? 438 ASP E CA 1 ATOM 8913 C C . ASP C 1 367 ? -14.304 -236.710 21.174 1.00 115.53 ? 438 ASP E C 1 ATOM 8914 O O . ASP C 1 367 ? -14.099 -237.809 20.655 1.00 109.17 ? 438 ASP E O 1 ATOM 8915 C CB . ASP C 1 367 ? -16.714 -237.117 21.750 1.00 113.21 ? 438 ASP E CB 1 ATOM 8916 C CG . ASP C 1 367 ? -17.451 -236.175 20.817 1.00 112.27 ? 438 ASP E CG 1 ATOM 8917 O OD1 . ASP C 1 367 ? -16.787 -235.388 20.110 1.00 104.06 ? 438 ASP E OD1 1 ATOM 8918 O OD2 . ASP C 1 367 ? -18.699 -236.223 20.794 1.00 97.44 ? 438 ASP E OD2 1 ATOM 8919 N N . LYS C 1 368 ? -13.621 -235.616 20.850 1.00 101.05 ? 439 LYS E N 1 ATOM 8920 C CA . LYS C 1 368 ? -12.437 -235.658 19.997 1.00 101.39 ? 439 LYS E CA 1 ATOM 8921 C C . LYS C 1 368 ? -11.223 -235.183 20.789 1.00 100.22 ? 439 LYS E C 1 ATOM 8922 O O . LYS C 1 368 ? -10.083 -235.320 20.341 1.00 85.09 ? 439 LYS E O 1 ATOM 8923 C CB . LYS C 1 368 ? -12.639 -234.802 18.747 1.00 108.72 ? 439 LYS E CB 1 ATOM 8924 C CG . LYS C 1 368 ? -13.689 -235.364 17.804 1.00 121.61 ? 439 LYS E CG 1 ATOM 8925 C CD . LYS C 1 368 ? -14.241 -234.313 16.859 1.00 118.26 ? 439 LYS E CD 1 ATOM 8926 C CE . LYS C 1 368 ? -15.737 -234.499 16.662 1.00 113.60 ? 439 LYS E CE 1 ATOM 8927 N NZ . LYS C 1 368 ? -16.063 -235.832 16.085 1.00 103.64 ? 439 LYS E NZ 1 ATOM 8928 N N . PHE C 1 369 ? -11.484 -234.623 21.968 1.00 97.61 ? 440 PHE E N 1 ATOM 8929 C CA . PHE C 1 369 ? -10.430 -234.221 22.890 1.00 96.38 ? 440 PHE E CA 1 ATOM 8930 C C . PHE C 1 369 ? -10.441 -235.130 24.122 1.00 92.24 ? 440 PHE E C 1 ATOM 8931 O O . PHE C 1 369 ? -11.192 -234.888 25.067 1.00 74.25 ? 440 PHE E O 1 ATOM 8932 C CB . PHE C 1 369 ? -10.601 -232.757 23.303 1.00 97.34 ? 440 PHE E CB 1 ATOM 8933 C CG . PHE C 1 369 ? -9.361 -232.150 23.897 1.00 79.69 ? 440 PHE E CG 1 ATOM 8934 C CD1 . PHE C 1 369 ? -8.366 -231.642 23.078 1.00 71.77 ? 440 PHE E CD1 1 ATOM 8935 C CD2 . PHE C 1 369 ? -9.183 -232.095 25.270 1.00 84.02 ? 440 PHE E CD2 1 ATOM 8936 C CE1 . PHE C 1 369 ? -7.220 -231.088 23.615 1.00 69.80 ? 440 PHE E CE1 1 ATOM 8937 C CE2 . PHE C 1 369 ? -8.038 -231.541 25.813 1.00 75.47 ? 440 PHE E CE2 1 ATOM 8938 C CZ . PHE C 1 369 ? -7.056 -231.038 24.984 1.00 73.52 ? 440 PHE E CZ 1 ATOM 8939 N N . PRO C 1 370 ? -9.614 -236.191 24.114 1.00 95.44 ? 441 PRO E N 1 ATOM 8940 C CA . PRO C 1 370 ? -9.586 -237.109 25.259 1.00 96.40 ? 441 PRO E CA 1 ATOM 8941 C C . PRO C 1 370 ? -8.869 -236.523 26.472 1.00 80.03 ? 441 PRO E C 1 ATOM 8942 O O . PRO C 1 370 ? -7.823 -235.892 26.315 1.00 64.71 ? 441 PRO E O 1 ATOM 8943 C CB . PRO C 1 370 ? -8.826 -238.321 24.713 1.00 72.76 ? 441 PRO E CB 1 ATOM 8944 C CG . PRO C 1 370 ? -7.922 -237.747 23.676 1.00 71.76 ? 441 PRO E CG 1 ATOM 8945 C CD . PRO C 1 370 ? -8.690 -236.616 23.046 1.00 73.85 ? 441 PRO E CD 1 ATOM 8946 N N . ASP C 1 371 ? -9.431 -236.724 27.661 1.00 74.56 ? 442 ASP E N 1 ATOM 8947 C CA . ASP C 1 371 ? -8.774 -236.308 28.894 1.00 64.13 ? 442 ASP E CA 1 ATOM 8948 C C . ASP C 1 371 ? -7.404 -236.966 28.987 1.00 62.75 ? 442 ASP E C 1 ATOM 8949 O O . ASP C 1 371 ? -7.259 -238.156 28.702 1.00 72.23 ? 442 ASP E O 1 ATOM 8950 C CB . ASP C 1 371 ? -9.625 -236.666 30.115 1.00 58.63 ? 442 ASP E CB 1 ATOM 8951 C CG . ASP C 1 371 ? -10.935 -235.904 30.154 1.00 76.99 ? 442 ASP E CG 1 ATOM 8952 O OD1 . ASP C 1 371 ? -11.428 -235.516 29.073 1.00 79.39 ? 442 ASP E OD1 1 ATOM 8953 O OD2 . ASP C 1 371 ? -11.469 -235.691 31.263 1.00 72.91 ? 442 ASP E OD2 1 ATOM 8954 N N . SER C 1 372 ? -6.403 -236.181 29.370 1.00 55.19 ? 443 SER E N 1 ATOM 8955 C CA . SER C 1 372 ? -5.031 -236.666 29.458 1.00 58.42 ? 443 SER E CA 1 ATOM 8956 C C . SER C 1 372 ? -4.346 -236.194 30.733 1.00 59.90 ? 443 SER E C 1 ATOM 8957 O O . SER C 1 372 ? -4.271 -234.995 31.006 1.00 63.55 ? 443 SER E O 1 ATOM 8958 C CB . SER C 1 372 ? -4.225 -236.208 28.241 1.00 52.56 ? 443 SER E CB 1 ATOM 8959 O OG . SER C 1 372 ? -2.854 -236.529 28.399 1.00 61.98 ? 443 SER E OG 1 ATOM 8960 N N . PHE C 1 373 ? -3.852 -237.155 31.509 1.00 59.94 ? 444 PHE E N 1 ATOM 8961 C CA . PHE C 1 373 ? -3.046 -236.868 32.688 1.00 46.53 ? 444 PHE E CA 1 ATOM 8962 C C . PHE C 1 373 ? -1.569 -237.036 32.350 1.00 43.31 ? 444 PHE E C 1 ATOM 8963 O O . PHE C 1 373 ? -1.213 -237.850 31.496 1.00 46.35 ? 444 PHE E O 1 ATOM 8964 C CB . PHE C 1 373 ? -3.432 -237.782 33.851 1.00 45.39 ? 444 PHE E CB 1 ATOM 8965 C CG . PHE C 1 373 ? -4.818 -237.543 34.376 1.00 49.37 ? 444 PHE E CG 1 ATOM 8966 C CD1 . PHE C 1 373 ? -5.908 -238.177 33.805 1.00 55.27 ? 444 PHE E CD1 1 ATOM 8967 C CD2 . PHE C 1 373 ? -5.032 -236.686 35.444 1.00 49.20 ? 444 PHE E CD2 1 ATOM 8968 C CE1 . PHE C 1 373 ? -7.185 -237.959 34.286 1.00 55.69 ? 444 PHE E CE1 1 ATOM 8969 C CE2 . PHE C 1 373 ? -6.308 -236.464 35.930 1.00 56.37 ? 444 PHE E CE2 1 ATOM 8970 C CZ . PHE C 1 373 ? -7.385 -237.102 35.350 1.00 57.79 ? 444 PHE E CZ 1 ATOM 8971 N N . GLY C 1 374 ? -0.719 -236.260 33.016 1.00 48.60 ? 445 GLY E N 1 ATOM 8972 C CA . GLY C 1 374 ? 0.720 -236.356 32.838 1.00 38.30 ? 445 GLY E CA 1 ATOM 8973 C C . GLY C 1 374 ? 1.359 -237.099 33.995 1.00 46.76 ? 445 GLY E C 1 ATOM 8974 O O . GLY C 1 374 ? 0.681 -237.463 34.956 1.00 43.34 ? 445 GLY E O 1 ATOM 8975 N N . ALA C 1 375 ? 2.666 -237.327 33.902 1.00 37.70 ? 446 ALA E N 1 ATOM 8976 C CA . ALA C 1 375 ? 3.401 -238.004 34.964 1.00 43.49 ? 446 ALA E CA 1 ATOM 8977 C C . ALA C 1 375 ? 3.451 -237.142 36.216 1.00 56.43 ? 446 ALA E C 1 ATOM 8978 O O . ALA C 1 375 ? 3.331 -235.919 36.147 1.00 50.60 ? 446 ALA E O 1 ATOM 8979 C CB . ALA C 1 375 ? 4.806 -238.345 34.507 1.00 49.25 ? 446 ALA E CB 1 ATOM 8980 N N . CYS C 1 376 ? 3.637 -237.788 37.361 1.00 47.67 ? 447 CYS E N 1 ATOM 8981 C CA . CYS C 1 376 ? 3.647 -237.084 38.632 1.00 45.43 ? 447 CYS E CA 1 ATOM 8982 C C . CYS C 1 376 ? 4.926 -236.275 38.823 1.00 52.69 ? 447 CYS E C 1 ATOM 8983 O O . CYS C 1 376 ? 6.031 -236.792 38.648 1.00 43.67 ? 447 CYS E O 1 ATOM 8984 C CB . CYS C 1 376 ? 3.487 -238.071 39.787 1.00 52.60 ? 447 CYS E CB 1 ATOM 8985 S SG . CYS C 1 376 ? 3.202 -237.275 41.385 1.00 61.70 ? 447 CYS E SG 1 ATOM 8986 N N . ASP C 1 377 ? 4.765 -235.002 39.173 1.00 41.56 ? 448 ASP E N 1 ATOM 8987 C CA . ASP C 1 377 ? 5.886 -234.172 39.598 1.00 47.94 ? 448 ASP E CA 1 ATOM 8988 C C . ASP C 1 377 ? 6.092 -234.406 41.088 1.00 47.64 ? 448 ASP E C 1 ATOM 8989 O O . ASP C 1 377 ? 5.448 -233.769 41.920 1.00 38.25 ? 448 ASP E O 1 ATOM 8990 C CB . ASP C 1 377 ? 5.624 -232.693 39.300 1.00 49.69 ? 448 ASP E CB 1 ATOM 8991 C CG . ASP C 1 377 ? 6.753 -231.790 39.767 1.00 58.63 ? 448 ASP E CG 1 ATOM 8992 O OD1 . ASP C 1 377 ? 7.877 -232.293 39.983 1.00 58.46 ? 448 ASP E OD1 1 ATOM 8993 O OD2 . ASP C 1 377 ? 6.518 -230.572 39.910 1.00 64.35 ? 448 ASP E OD2 1 ATOM 8994 N N . VAL C 1 378 ? 6.987 -235.333 41.414 1.00 44.98 ? 449 VAL E N 1 ATOM 8995 C CA . VAL C 1 378 ? 7.122 -235.834 42.779 1.00 48.58 ? 449 VAL E CA 1 ATOM 8996 C C . VAL C 1 378 ? 7.610 -234.784 43.773 1.00 46.82 ? 449 VAL E C 1 ATOM 8997 O O . VAL C 1 378 ? 7.444 -234.950 44.982 1.00 56.17 ? 449 VAL E O 1 ATOM 8998 C CB . VAL C 1 378 ? 8.083 -237.039 42.834 1.00 49.34 ? 449 VAL E CB 1 ATOM 8999 C CG1 . VAL C 1 378 ? 7.472 -238.228 42.112 1.00 50.40 ? 449 VAL E CG1 1 ATOM 9000 C CG2 . VAL C 1 378 ? 9.440 -236.684 42.239 1.00 45.14 ? 449 VAL E CG2 1 ATOM 9001 N N . GLN C 1 379 ? 8.210 -233.709 43.272 1.00 49.32 ? 450 GLN E N 1 ATOM 9002 C CA . GLN C 1 379 ? 8.704 -232.647 44.141 1.00 55.71 ? 450 GLN E CA 1 ATOM 9003 C C . GLN C 1 379 ? 7.563 -231.725 44.572 1.00 53.40 ? 450 GLN E C 1 ATOM 9004 O O . GLN C 1 379 ? 7.665 -231.027 45.581 1.00 56.07 ? 450 GLN E O 1 ATOM 9005 C CB . GLN C 1 379 ? 9.799 -231.843 43.439 1.00 62.01 ? 450 GLN E CB 1 ATOM 9006 C CG . GLN C 1 379 ? 10.766 -231.161 44.396 1.00 85.35 ? 450 GLN E CG 1 ATOM 9007 C CD . GLN C 1 379 ? 11.860 -230.398 43.676 1.00 113.02 ? 450 GLN E CD 1 ATOM 9008 O OE1 . GLN C 1 379 ? 12.482 -230.912 42.746 1.00 114.36 ? 450 GLN E OE1 1 ATOM 9009 N NE2 . GLN C 1 379 ? 12.097 -229.162 44.100 1.00 95.08 ? 450 GLN E NE2 1 ATOM 9010 N N . ALA C 1 380 ? 6.483 -231.728 43.795 1.00 51.30 ? 451 ALA E N 1 ATOM 9011 C CA . ALA C 1 380 ? 5.283 -230.958 44.114 1.00 52.27 ? 451 ALA E CA 1 ATOM 9012 C C . ALA C 1 380 ? 4.107 -231.890 44.391 1.00 51.32 ? 451 ALA E C 1 ATOM 9013 O O . ALA C 1 380 ? 3.108 -231.487 44.986 1.00 49.90 ? 451 ALA E O 1 ATOM 9014 C CB . ALA C 1 380 ? 4.947 -230.008 42.978 1.00 48.42 ? 451 ALA E CB 1 ATOM 9015 N N . CYS C 1 381 ? 4.245 -233.138 43.954 1.00 56.90 ? 452 CYS E N 1 ATOM 9016 C CA . CYS C 1 381 ? 3.188 -234.136 44.070 1.00 55.55 ? 452 CYS E CA 1 ATOM 9017 C C . CYS C 1 381 ? 1.913 -233.659 43.366 1.00 50.57 ? 452 CYS E C 1 ATOM 9018 O O . CYS C 1 381 ? 0.804 -233.792 43.886 1.00 47.72 ? 452 CYS E O 1 ATOM 9019 C CB . CYS C 1 381 ? 2.920 -234.464 45.541 1.00 58.58 ? 452 CYS E CB 1 ATOM 9020 S SG . CYS C 1 381 ? 2.622 -236.228 45.821 1.00 93.77 ? 452 CYS E SG 1 ATOM 9021 N N . LYS C 1 382 ? 2.096 -233.105 42.171 1.00 45.56 ? 453 LYS E N 1 ATOM 9022 C CA . LYS C 1 382 ? 0.987 -232.700 41.320 1.00 39.09 ? 453 LYS E CA 1 ATOM 9023 C C . LYS C 1 382 ? 1.225 -233.213 39.906 1.00 32.81 ? 453 LYS E C 1 ATOM 9024 O O . LYS C 1 382 ? 2.338 -233.618 39.567 1.00 32.11 ? 453 LYS E O 1 ATOM 9025 C CB . LYS C 1 382 ? 0.826 -231.179 41.310 1.00 45.72 ? 453 LYS E CB 1 ATOM 9026 C CG . LYS C 1 382 ? 0.661 -230.551 42.688 1.00 43.69 ? 453 LYS E CG 1 ATOM 9027 C CD . LYS C 1 382 ? -0.446 -229.503 42.694 1.00 57.41 ? 453 LYS E CD 1 ATOM 9028 C CE . LYS C 1 382 ? -1.805 -230.128 42.970 1.00 61.71 ? 453 LYS E CE 1 ATOM 9029 N NZ . LYS C 1 382 ? -2.163 -230.053 44.414 1.00 64.79 ? 453 LYS E NZ 1 ATOM 9030 N N . ARG C 1 383 ? 0.177 -233.203 39.088 1.00 33.20 ? 454 ARG E N 1 ATOM 9031 C CA . ARG C 1 383 ? 0.297 -233.625 37.695 1.00 46.93 ? 454 ARG E CA 1 ATOM 9032 C C . ARG C 1 383 ? -0.621 -232.825 36.775 1.00 27.87 ? 454 ARG E C 1 ATOM 9033 O O . ARG C 1 383 ? -1.666 -232.325 37.195 1.00 29.62 ? 454 ARG E O 1 ATOM 9034 C CB . ARG C 1 383 ? -0.016 -235.115 37.567 1.00 36.45 ? 454 ARG E CB 1 ATOM 9035 C CG . ARG C 1 383 ? -1.388 -235.491 38.098 1.00 35.93 ? 454 ARG E CG 1 ATOM 9036 C CD . ARG C 1 383 ? -1.696 -236.961 37.878 1.00 41.22 ? 454 ARG E CD 1 ATOM 9037 N NE . ARG C 1 383 ? -3.015 -237.310 38.396 1.00 49.45 ? 454 ARG E NE 1 ATOM 9038 C CZ . ARG C 1 383 ? -3.719 -238.372 38.018 1.00 48.14 ? 454 ARG E CZ 1 ATOM 9039 N NH1 . ARG C 1 383 ? -3.241 -239.208 37.105 1.00 40.16 ? 454 ARG E NH1 1 ATOM 9040 N NH2 . ARG C 1 383 ? -4.911 -238.595 38.551 1.00 38.76 ? 454 ARG E NH2 1 ATOM 9041 N N . GLN C 1 384 ? -0.223 -232.724 35.512 1.00 35.78 ? 455 GLN E N 1 ATOM 9042 C CA . GLN C 1 384 ? -0.997 -232.002 34.509 1.00 36.77 ? 455 GLN E CA 1 ATOM 9043 C C . GLN C 1 384 ? -2.269 -232.754 34.134 1.00 37.90 ? 455 GLN E C 1 ATOM 9044 O O . GLN C 1 384 ? -2.210 -233.919 33.749 1.00 47.58 ? 455 GLN E O 1 ATOM 9045 C CB . GLN C 1 384 ? -0.146 -231.771 33.255 1.00 39.85 ? 455 GLN E CB 1 ATOM 9046 C CG . GLN C 1 384 ? -0.856 -231.030 32.121 1.00 39.60 ? 455 GLN E CG 1 ATOM 9047 C CD . GLN C 1 384 ? -1.091 -229.562 32.425 1.00 45.17 ? 455 GLN E CD 1 ATOM 9048 O OE1 . GLN C 1 384 ? -0.292 -228.920 33.108 1.00 38.80 ? 455 GLN E OE1 1 ATOM 9049 N NE2 . GLN C 1 384 ? -2.193 -229.023 31.915 1.00 46.69 ? 455 GLN E NE2 1 ATOM 9050 N N . LYS C 1 385 ? -3.414 -232.085 34.262 1.00 35.56 ? 456 LYS E N 1 ATOM 9051 C CA . LYS C 1 385 ? -4.662 -232.568 33.677 1.00 35.36 ? 456 LYS E CA 1 ATOM 9052 C C . LYS C 1 385 ? -5.071 -231.660 32.524 1.00 47.84 ? 456 LYS E C 1 ATOM 9053 O O . LYS C 1 385 ? -5.109 -230.430 32.662 1.00 43.48 ? 456 LYS E O 1 ATOM 9054 C CB . LYS C 1 385 ? -5.789 -232.632 34.708 1.00 39.37 ? 456 LYS E CB 1 ATOM 9055 C CG . LYS C 1 385 ? -7.080 -233.218 34.137 1.00 41.19 ? 456 LYS E CG 1 ATOM 9056 C CD . LYS C 1 385 ? -8.251 -233.102 35.092 1.00 53.87 ? 456 LYS E CD 1 ATOM 9057 C CE . LYS C 1 385 ? -9.493 -233.742 34.491 1.00 57.40 ? 456 LYS E CE 1 ATOM 9058 N NZ . LYS C 1 385 ? -10.706 -233.535 35.326 1.00 64.92 ? 456 LYS E NZ 1 ATOM 9059 N N . THR C 1 386 ? -5.385 -232.291 31.396 1.00 53.54 ? 457 THR E N 1 ATOM 9060 C CA . THR C 1 386 ? -5.748 -231.596 30.168 1.00 53.61 ? 457 THR E CA 1 ATOM 9061 C C . THR C 1 386 ? -7.052 -232.158 29.610 1.00 54.86 ? 457 THR E C 1 ATOM 9062 O O . THR C 1 386 ? -7.091 -233.306 29.163 1.00 58.45 ? 457 THR E O 1 ATOM 9063 C CB . THR C 1 386 ? -4.643 -231.730 29.105 1.00 42.04 ? 457 THR E CB 1 ATOM 9064 O OG1 . THR C 1 386 ? -3.374 -231.408 29.687 1.00 45.33 ? 457 THR E OG1 1 ATOM 9065 C CG2 . THR C 1 386 ? -4.914 -230.805 27.929 1.00 47.61 ? 457 THR E CG2 1 ATOM 9066 N N . SER C 1 387 ? -8.111 -231.353 29.633 1.00 52.54 ? 458 SER E N 1 ATOM 9067 C CA . SER C 1 387 ? -9.427 -231.810 29.182 1.00 57.34 ? 458 SER E CA 1 ATOM 9068 C C . SER C 1 387 ? -10.132 -230.765 28.319 1.00 60.45 ? 458 SER E C 1 ATOM 9069 O O . SER C 1 387 ? -9.544 -229.745 27.960 1.00 64.93 ? 458 SER E O 1 ATOM 9070 C CB . SER C 1 387 ? -10.305 -232.174 30.386 1.00 54.68 ? 458 SER E CB 1 ATOM 9071 O OG . SER C 1 387 ? -10.484 -231.069 31.253 1.00 57.81 ? 458 SER E OG 1 ATOM 9072 N N . CYS C 1 388 ? -11.386 -231.044 27.973 1.00 58.67 ? 459 CYS E N 1 ATOM 9073 C CA . CYS C 1 388 ? -12.208 -230.125 27.196 1.00 51.96 ? 459 CYS E CA 1 ATOM 9074 C C . CYS C 1 388 ? -13.548 -229.896 27.887 1.00 57.33 ? 459 CYS E C 1 ATOM 9075 O O . CYS C 1 388 ? -14.379 -230.803 27.958 1.00 66.36 ? 459 CYS E O 1 ATOM 9076 C CB . CYS C 1 388 ? -12.435 -230.664 25.783 1.00 72.51 ? 459 CYS E CB 1 ATOM 9077 S SG . CYS C 1 388 ? -13.316 -229.521 24.693 1.00 98.58 ? 459 CYS E SG 1 ATOM 9078 N N . VAL C 1 389 ? -13.754 -228.681 28.386 1.00 57.32 ? 460 VAL E N 1 ATOM 9079 C CA . VAL C 1 389 ? -14.979 -228.331 29.100 1.00 60.40 ? 460 VAL E CA 1 ATOM 9080 C C . VAL C 1 389 ? -15.625 -227.116 28.452 1.00 73.22 ? 460 VAL E C 1 ATOM 9081 O O . VAL C 1 389 ? -14.949 -226.143 28.118 1.00 71.79 ? 460 VAL E O 1 ATOM 9082 C CB . VAL C 1 389 ? -14.708 -228.039 30.593 1.00 64.24 ? 460 VAL E CB 1 ATOM 9083 C CG1 . VAL C 1 389 ? -15.953 -227.483 31.288 1.00 61.63 ? 460 VAL E CG1 1 ATOM 9084 C CG2 . VAL C 1 389 ? -14.229 -229.304 31.302 1.00 64.87 ? 460 VAL E CG2 1 ATOM 9085 N N . GLY C 1 390 ? -16.941 -227.187 28.280 1.00 74.59 ? 461 GLY E N 1 ATOM 9086 C CA . GLY C 1 390 ? -17.707 -226.096 27.708 1.00 67.16 ? 461 GLY E CA 1 ATOM 9087 C C . GLY C 1 390 ? -17.222 -225.686 26.331 1.00 80.06 ? 461 GLY E C 1 ATOM 9088 O O . GLY C 1 390 ? -17.426 -224.548 25.907 1.00 80.89 ? 461 GLY E O 1 ATOM 9089 N N . GLY C 1 391 ? -16.577 -226.616 25.632 1.00 75.23 ? 462 GLY E N 1 ATOM 9090 C CA . GLY C 1 391 ? -16.063 -226.356 24.300 1.00 56.91 ? 462 GLY E CA 1 ATOM 9091 C C . GLY C 1 391 ? -14.674 -225.742 24.306 1.00 76.28 ? 462 GLY E C 1 ATOM 9092 O O . GLY C 1 391 ? -14.148 -225.384 23.250 1.00 74.05 ? 462 GLY E O 1 ATOM 9093 N N . GLN C 1 392 ? -14.079 -225.625 25.491 1.00 76.80 ? 463 GLN E N 1 ATOM 9094 C CA . GLN C 1 392 ? -12.762 -225.007 25.643 1.00 75.60 ? 463 GLN E CA 1 ATOM 9095 C C . GLN C 1 392 ? -11.781 -225.927 26.363 1.00 67.29 ? 463 GLN E C 1 ATOM 9096 O O . GLN C 1 392 ? -12.176 -226.746 27.195 1.00 56.31 ? 463 GLN E O 1 ATOM 9097 C CB . GLN C 1 392 ? -12.885 -223.681 26.401 1.00 72.01 ? 463 GLN E CB 1 ATOM 9098 C CG . GLN C 1 392 ? -13.664 -222.602 25.647 1.00 80.61 ? 463 GLN E CG 1 ATOM 9099 C CD . GLN C 1 392 ? -12.860 -221.957 24.527 1.00 92.58 ? 463 GLN E CD 1 ATOM 9100 O OE1 . GLN C 1 392 ? -11.665 -221.699 24.673 1.00 90.50 ? 463 GLN E OE1 1 ATOM 9101 N NE2 . GLN C 1 392 ? -13.518 -221.690 23.401 1.00 89.33 ? 463 GLN E NE2 1 ATOM 9102 N N . ILE C 1 393 ? -10.500 -225.786 26.033 1.00 51.22 ? 464 ILE E N 1 ATOM 9103 C CA . ILE C 1 393 ? -9.450 -226.549 26.695 1.00 60.18 ? 464 ILE E CA 1 ATOM 9104 C C . ILE C 1 393 ? -9.332 -226.155 28.160 1.00 58.63 ? 464 ILE E C 1 ATOM 9105 O O . ILE C 1 393 ? -9.303 -224.969 28.497 1.00 45.71 ? 464 ILE E O 1 ATOM 9106 C CB . ILE C 1 393 ? -8.073 -226.350 26.020 1.00 51.73 ? 464 ILE E CB 1 ATOM 9107 C CG1 . ILE C 1 393 ? -8.131 -226.821 24.563 1.00 58.22 ? 464 ILE E CG1 1 ATOM 9108 C CG2 . ILE C 1 393 ? -6.976 -227.090 26.805 1.00 49.69 ? 464 ILE E CG2 1 ATOM 9109 C CD1 . ILE C 1 393 ? -6.777 -226.955 23.877 1.00 76.41 ? 464 ILE E CD1 1 ATOM 9110 N N . GLN C 1 394 ? -9.264 -227.166 29.020 1.00 46.47 ? 465 GLN E N 1 ATOM 9111 C CA . GLN C 1 394 ? -8.945 -226.980 30.427 1.00 40.00 ? 465 GLN E CA 1 ATOM 9112 C C . GLN C 1 394 ? -7.571 -227.561 30.700 1.00 46.89 ? 465 GLN E C 1 ATOM 9113 O O . GLN C 1 394 ? -7.343 -228.756 30.494 1.00 50.85 ? 465 GLN E O 1 ATOM 9114 C CB . GLN C 1 394 ? -9.977 -227.656 31.327 1.00 56.12 ? 465 GLN E CB 1 ATOM 9115 C CG . GLN C 1 394 ? -11.403 -227.202 31.116 1.00 68.02 ? 465 GLN E CG 1 ATOM 9116 C CD . GLN C 1 394 ? -11.759 -225.982 31.940 1.00 86.17 ? 465 GLN E CD 1 ATOM 9117 O OE1 . GLN C 1 394 ? -11.771 -226.033 33.171 1.00 75.87 ? 465 GLN E OE1 1 ATOM 9118 N NE2 . GLN C 1 394 ? -12.053 -224.874 31.266 1.00 74.41 ? 465 GLN E NE2 1 ATOM 9119 N N . SER C 1 395 ? -6.662 -226.703 31.150 1.00 42.15 ? 466 SER E N 1 ATOM 9120 C CA . SER C 1 395 ? -5.329 -227.115 31.563 1.00 39.13 ? 466 SER E CA 1 ATOM 9121 C C . SER C 1 395 ? -5.134 -226.782 33.033 1.00 50.71 ? 466 SER E C 1 ATOM 9122 O O . SER C 1 395 ? -5.126 -225.609 33.413 1.00 38.56 ? 466 SER E O 1 ATOM 9123 C CB . SER C 1 395 ? -4.260 -226.426 30.717 1.00 35.41 ? 466 SER E CB 1 ATOM 9124 O OG . SER C 1 395 ? -3.000 -226.488 31.357 1.00 40.90 ? 466 SER E OG 1 ATOM 9125 N N . THR C 1 396 ? -4.989 -227.814 33.861 1.00 35.46 ? 467 THR E N 1 ATOM 9126 C CA . THR C 1 396 ? -4.831 -227.613 35.298 1.00 33.47 ? 467 THR E CA 1 ATOM 9127 C C . THR C 1 396 ? -3.794 -228.559 35.891 1.00 36.92 ? 467 THR E C 1 ATOM 9128 O O . THR C 1 396 ? -3.310 -229.472 35.220 1.00 29.43 ? 467 THR E O 1 ATOM 9129 C CB . THR C 1 396 ? -6.167 -227.811 36.047 1.00 50.15 ? 467 THR E CB 1 ATOM 9130 O OG1 . THR C 1 396 ? -6.692 -229.115 35.767 1.00 53.84 ? 467 THR E OG1 1 ATOM 9131 C CG2 . THR C 1 396 ? -7.182 -226.755 35.627 1.00 45.27 ? 467 THR E CG2 1 ATOM 9132 N N . SER C 1 397 ? -3.447 -228.311 37.150 1.00 34.93 ? 468 SER E N 1 ATOM 9133 C CA . SER C 1 397 ? -2.597 -229.207 37.918 1.00 39.56 ? 468 SER E CA 1 ATOM 9134 C C . SER C 1 397 ? -3.431 -229.842 39.021 1.00 40.37 ? 468 SER E C 1 ATOM 9135 O O . SER C 1 397 ? -4.081 -229.141 39.797 1.00 41.45 ? 468 SER E O 1 ATOM 9136 C CB . SER C 1 397 ? -1.397 -228.463 38.505 1.00 44.60 ? 468 SER E CB 1 ATOM 9137 O OG . SER C 1 397 ? -0.305 -228.467 37.601 1.00 44.25 ? 468 SER E OG 1 ATOM 9138 N N . VAL C 1 398 ? -3.417 -231.171 39.074 1.00 45.91 ? 469 VAL E N 1 ATOM 9139 C CA . VAL C 1 398 ? -4.227 -231.917 40.030 1.00 46.83 ? 469 VAL E CA 1 ATOM 9140 C C . VAL C 1 398 ? -3.378 -232.890 40.837 1.00 40.04 ? 469 VAL E C 1 ATOM 9141 O O . VAL C 1 398 ? -2.199 -233.108 40.535 1.00 32.86 ? 469 VAL E O 1 ATOM 9142 C CB . VAL C 1 398 ? -5.349 -232.703 39.321 1.00 43.76 ? 469 VAL E CB 1 ATOM 9143 C CG1 . VAL C 1 398 ? -6.323 -231.744 38.655 1.00 46.50 ? 469 VAL E CG1 1 ATOM 9144 C CG2 . VAL C 1 398 ? -4.766 -233.675 38.299 1.00 38.24 ? 469 VAL E CG2 1 ATOM 9145 N N . ASP C 1 399 ? -3.995 -233.472 41.862 1.00 50.97 ? 470 ASP E N 1 ATOM 9146 C CA . ASP C 1 399 ? -3.339 -234.461 42.705 1.00 45.30 ? 470 ASP E CA 1 ATOM 9147 C C . ASP C 1 399 ? -2.910 -235.675 41.898 1.00 35.42 ? 470 ASP E C 1 ATOM 9148 O O . ASP C 1 399 ? -3.608 -236.100 40.977 1.00 42.90 ? 470 ASP E O 1 ATOM 9149 C CB . ASP C 1 399 ? -4.269 -234.906 43.834 1.00 47.98 ? 470 ASP E CB 1 ATOM 9150 C CG . ASP C 1 399 ? -4.588 -233.788 44.804 1.00 64.30 ? 470 ASP E CG 1 ATOM 9151 O OD1 . ASP C 1 399 ? -3.765 -232.858 44.938 1.00 59.32 ? 470 ASP E OD1 1 ATOM 9152 O OD2 . ASP C 1 399 ? -5.663 -233.842 45.438 1.00 76.73 ? 470 ASP E OD2 1 ATOM 9153 N N . CYS C 1 400 ? -1.756 -236.229 42.249 1.00 41.62 ? 471 CYS E N 1 ATOM 9154 C CA . CYS C 1 400 ? -1.310 -237.482 41.663 1.00 50.12 ? 471 CYS E CA 1 ATOM 9155 C C . CYS C 1 400 ? -2.194 -238.615 42.173 1.00 38.09 ? 471 CYS E C 1 ATOM 9156 O O . CYS C 1 400 ? -2.905 -238.451 43.166 1.00 43.58 ? 471 CYS E O 1 ATOM 9157 C CB . CYS C 1 400 ? 0.156 -237.747 42.009 1.00 61.44 ? 471 CYS E CB 1 ATOM 9158 S SG . CYS C 1 400 ? 1.316 -236.513 41.372 1.00 61.41 ? 471 CYS E SG 1 ATOM 9159 N N . THR C 1 401 ? -2.160 -239.757 41.493 1.00 53.45 ? 472 THR E N 1 ATOM 9160 C CA . THR C 1 401 ? -2.887 -240.934 41.957 1.00 60.28 ? 472 THR E CA 1 ATOM 9161 C C . THR C 1 401 ? -2.385 -241.314 43.342 1.00 59.63 ? 472 THR E C 1 ATOM 9162 O O . THR C 1 401 ? -1.188 -241.219 43.609 1.00 55.50 ? 472 THR E O 1 ATOM 9163 C CB . THR C 1 401 ? -2.709 -242.137 41.014 1.00 50.58 ? 472 THR E CB 1 ATOM 9164 O OG1 . THR C 1 401 ? -1.344 -242.570 41.042 1.00 56.71 ? 472 THR E OG1 1 ATOM 9165 C CG2 . THR C 1 401 ? -3.098 -241.775 39.589 1.00 55.00 ? 472 THR E CG2 1 ATOM 9166 N N . ALA C 1 402 ? -3.294 -241.743 44.215 1.00 70.04 ? 473 ALA E N 1 ATOM 9167 C CA . ALA C 1 402 ? -2.937 -242.118 45.585 1.00 69.30 ? 473 ALA E CA 1 ATOM 9168 C C . ALA C 1 402 ? -1.761 -243.096 45.608 1.00 63.88 ? 473 ALA E C 1 ATOM 9169 O O . ALA C 1 402 ? -0.996 -243.142 46.572 1.00 65.82 ? 473 ALA E O 1 ATOM 9170 C CB . ALA C 1 402 ? -4.140 -242.717 46.298 1.00 62.99 ? 473 ALA E CB 1 ATOM 9171 N N . ASP C 1 403 ? -1.629 -243.872 44.537 1.00 63.57 ? 474 ASP E N 1 ATOM 9172 C CA . ASP C 1 403 ? -0.464 -244.722 44.323 1.00 64.53 ? 474 ASP E CA 1 ATOM 9173 C C . ASP C 1 403 ? 0.789 -243.859 44.195 1.00 77.21 ? 474 ASP E C 1 ATOM 9174 O O . ASP C 1 403 ? 1.751 -244.029 44.945 1.00 76.68 ? 474 ASP E O 1 ATOM 9175 C CB . ASP C 1 403 ? -0.668 -245.584 43.069 1.00 71.78 ? 474 ASP E CB 1 ATOM 9176 C CG . ASP C 1 403 ? 0.527 -246.475 42.750 1.00 92.02 ? 474 ASP E CG 1 ATOM 9177 O OD1 . ASP C 1 403 ? 1.649 -245.958 42.564 1.00 85.72 ? 474 ASP E OD1 1 ATOM 9178 O OD2 . ASP C 1 403 ? 0.333 -247.707 42.670 1.00 99.52 ? 474 ASP E OD2 1 ATOM 9179 N N . GLU C 1 404 ? 0.762 -242.932 43.243 1.00 69.05 ? 475 GLU E N 1 ATOM 9180 C CA . GLU C 1 404 ? 1.907 -242.073 42.959 1.00 65.32 ? 475 GLU E CA 1 ATOM 9181 C C . GLU C 1 404 ? 2.355 -241.277 44.185 1.00 53.28 ? 475 GLU E C 1 ATOM 9182 O O . GLU C 1 404 ? 3.532 -240.940 44.319 1.00 52.10 ? 475 GLU E O 1 ATOM 9183 C CB . GLU C 1 404 ? 1.571 -241.114 41.813 1.00 66.27 ? 475 GLU E CB 1 ATOM 9184 C CG . GLU C 1 404 ? 1.608 -241.755 40.431 1.00 59.95 ? 475 GLU E CG 1 ATOM 9185 C CD . GLU C 1 404 ? 1.023 -240.865 39.342 1.00 68.47 ? 475 GLU E CD 1 ATOM 9186 O OE1 . GLU C 1 404 ? 1.476 -240.968 38.183 1.00 62.26 ? 475 GLU E OE1 1 ATOM 9187 O OE2 . GLU C 1 404 ? 0.106 -240.069 39.639 1.00 52.79 ? 475 GLU E OE2 1 ATOM 9188 N N . GLN C 1 405 ? 1.416 -240.989 45.082 1.00 47.67 ? 476 GLN E N 1 ATOM 9189 C CA . GLN C 1 405 ? 1.707 -240.180 46.264 1.00 65.86 ? 476 GLN E CA 1 ATOM 9190 C C . GLN C 1 405 ? 2.668 -240.885 47.220 1.00 64.16 ? 476 GLN E C 1 ATOM 9191 O O . GLN C 1 405 ? 3.197 -240.267 48.144 1.00 57.16 ? 476 GLN E O 1 ATOM 9192 C CB . GLN C 1 405 ? 0.411 -239.823 46.995 1.00 62.50 ? 476 GLN E CB 1 ATOM 9193 C CG . GLN C 1 405 ? -0.582 -239.059 46.134 1.00 56.60 ? 476 GLN E CG 1 ATOM 9194 C CD . GLN C 1 405 ? -1.842 -238.674 46.880 1.00 57.35 ? 476 GLN E CD 1 ATOM 9195 O OE1 . GLN C 1 405 ? -1.940 -238.852 48.095 1.00 64.10 ? 476 GLN E OE1 1 ATOM 9196 N NE2 . GLN C 1 405 ? -2.818 -238.142 46.153 1.00 64.98 ? 476 GLN E NE2 1 ATOM 9197 N N . ASN C 1 406 ? 2.890 -242.177 46.999 1.00 68.97 ? 477 ASN E N 1 ATOM 9198 C CA . ASN C 1 406 ? 3.873 -242.926 47.773 1.00 78.77 ? 477 ASN E CA 1 ATOM 9199 C C . ASN C 1 406 ? 5.295 -242.597 47.331 1.00 77.42 ? 477 ASN E C 1 ATOM 9200 O O . ASN C 1 406 ? 6.263 -242.966 47.998 1.00 66.54 ? 477 ASN E O 1 ATOM 9201 C CB . ASN C 1 406 ? 3.624 -244.429 47.645 1.00 78.95 ? 477 ASN E CB 1 ATOM 9202 C CG . ASN C 1 406 ? 2.315 -244.859 48.279 1.00 75.39 ? 477 ASN E CG 1 ATOM 9203 O OD1 . ASN C 1 406 ? 1.865 -244.269 49.262 1.00 71.87 ? 477 ASN E OD1 1 ATOM 9204 N ND2 . ASN C 1 406 ? 1.697 -245.893 47.720 1.00 52.47 ? 477 ASN E ND2 1 ATOM 9205 N N . GLU C 1 407 ? 5.411 -241.901 46.204 1.00 69.19 ? 478 GLU E N 1 ATOM 9206 C CA . GLU C 1 407 ? 6.708 -241.531 45.652 1.00 54.44 ? 478 GLU E CA 1 ATOM 9207 C C . GLU C 1 407 ? 7.057 -240.082 45.996 1.00 55.53 ? 478 GLU E C 1 ATOM 9208 O O . GLU C 1 407 ? 8.155 -239.613 45.695 1.00 49.23 ? 478 GLU E O 1 ATOM 9209 C CB . GLU C 1 407 ? 6.711 -241.731 44.133 1.00 70.36 ? 478 GLU E CB 1 ATOM 9210 C CG . GLU C 1 407 ? 5.989 -242.996 43.670 1.00 83.69 ? 478 GLU E CG 1 ATOM 9211 C CD . GLU C 1 407 ? 5.915 -243.114 42.160 1.00 92.33 ? 478 GLU E CD 1 ATOM 9212 O OE1 . GLU C 1 407 ? 4.979 -243.773 41.659 1.00 86.69 ? 478 GLU E OE1 1 ATOM 9213 O OE2 . GLU C 1 407 ? 6.791 -242.551 41.471 1.00 78.57 ? 478 GLU E OE2 1 ATOM 9214 N N . CYS C 1 408 ? 6.122 -239.385 46.637 1.00 48.48 ? 479 CYS E N 1 ATOM 9215 C CA . CYS C 1 408 ? 6.280 -237.965 46.938 1.00 54.44 ? 479 CYS E CA 1 ATOM 9216 C C . CYS C 1 408 ? 6.820 -237.750 48.348 1.00 57.60 ? 479 CYS E C 1 ATOM 9217 O O . CYS C 1 408 ? 7.049 -238.705 49.090 1.00 65.57 ? 479 CYS E O 1 ATOM 9218 C CB . CYS C 1 408 ? 4.940 -237.235 46.785 1.00 66.65 ? 479 CYS E CB 1 ATOM 9219 S SG . CYS C 1 408 ? 4.205 -237.308 45.130 1.00 68.95 ? 479 CYS E SG 1 ATOM 9220 N N . GLY C 1 409 ? 7.025 -236.486 48.706 1.00 61.24 ? 480 GLY E N 1 ATOM 9221 C CA . GLY C 1 409 ? 7.409 -236.123 50.058 1.00 65.56 ? 480 GLY E CA 1 ATOM 9222 C C . GLY C 1 409 ? 6.255 -236.306 51.027 1.00 58.24 ? 480 GLY E C 1 ATOM 9223 O O . GLY C 1 409 ? 6.346 -235.940 52.199 1.00 65.59 ? 480 GLY E O 1 ATOM 9224 N N . SER D 2 2 ? 35.218 -187.087 53.521 1.00 75.13 ? 1259 SER B N 1 ATOM 9225 C CA . SER D 2 2 ? 33.804 -186.831 53.767 1.00 92.75 ? 1259 SER B CA 1 ATOM 9226 C C . SER D 2 2 ? 33.613 -185.697 54.772 1.00 97.17 ? 1259 SER B C 1 ATOM 9227 O O . SER D 2 2 ? 32.527 -185.125 54.873 1.00 96.92 ? 1259 SER B O 1 ATOM 9228 C CB . SER D 2 2 ? 33.112 -188.102 54.264 1.00 93.53 ? 1259 SER B CB 1 ATOM 9229 O OG . SER D 2 2 ? 33.091 -189.096 53.253 1.00 92.82 ? 1259 SER B OG 1 ATOM 9230 N N . ALA D 2 3 ? 34.673 -185.384 55.514 1.00 96.39 ? 1260 ALA B N 1 ATOM 9231 C CA . ALA D 2 3 ? 34.684 -184.234 56.414 1.00 92.50 ? 1260 ALA B CA 1 ATOM 9232 C C . ALA D 2 3 ? 35.696 -183.208 55.912 1.00 88.67 ? 1260 ALA B C 1 ATOM 9233 O O . ALA D 2 3 ? 35.532 -182.004 56.112 1.00 79.61 ? 1260 ALA B O 1 ATOM 9234 C CB . ALA D 2 3 ? 35.007 -184.666 57.833 1.00 81.24 ? 1260 ALA B CB 1 ATOM 9235 N N . SER D 2 4 ? 36.744 -183.701 55.259 1.00 84.33 ? 1261 SER B N 1 ATOM 9236 C CA . SER D 2 4 ? 37.700 -182.845 54.568 1.00 85.39 ? 1261 SER B CA 1 ATOM 9237 C C . SER D 2 4 ? 37.040 -182.261 53.325 1.00 88.35 ? 1261 SER B C 1 ATOM 9238 O O . SER D 2 4 ? 37.309 -181.123 52.946 1.00 80.21 ? 1261 SER B O 1 ATOM 9239 C CB . SER D 2 4 ? 38.961 -183.636 54.203 1.00 77.33 ? 1261 SER B CB 1 ATOM 9240 O OG . SER D 2 4 ? 39.690 -183.027 53.151 1.00 90.02 ? 1261 SER B OG 1 ATOM 9241 N N . ASP D 2 5 ? 36.165 -183.048 52.704 1.00 90.54 ? 1262 ASP B N 1 ATOM 9242 C CA . ASP D 2 5 ? 35.417 -182.611 51.530 1.00 85.98 ? 1262 ASP B CA 1 ATOM 9243 C C . ASP D 2 5 ? 34.504 -181.440 51.874 1.00 74.65 ? 1262 ASP B C 1 ATOM 9244 O O . ASP D 2 5 ? 34.414 -180.475 51.119 1.00 68.11 ? 1262 ASP B O 1 ATOM 9245 C CB . ASP D 2 5 ? 34.598 -183.772 50.956 1.00 92.30 ? 1262 ASP B CB 1 ATOM 9246 C CG . ASP D 2 5 ? 35.384 -184.608 49.961 1.00 97.67 ? 1262 ASP B CG 1 ATOM 9247 O OD1 . ASP D 2 5 ? 36.632 -184.592 50.021 1.00 95.28 ? 1262 ASP B OD1 1 ATOM 9248 O OD2 . ASP D 2 5 ? 34.752 -185.284 49.121 1.00 88.69 ? 1262 ASP B OD2 1 ATOM 9249 N N . ILE D 2 6 ? 33.833 -181.533 53.018 1.00 71.93 ? 1263 ILE B N 1 ATOM 9250 C CA . ILE D 2 6 ? 32.958 -180.467 53.497 1.00 72.20 ? 1263 ILE B CA 1 ATOM 9251 C C . ILE D 2 6 ? 33.767 -179.198 53.749 1.00 65.45 ? 1263 ILE B C 1 ATOM 9252 O O . ILE D 2 6 ? 33.360 -178.102 53.365 1.00 57.92 ? 1263 ILE B O 1 ATOM 9253 C CB . ILE D 2 6 ? 32.211 -180.905 54.782 1.00 68.03 ? 1263 ILE B CB 1 ATOM 9254 C CG1 . ILE D 2 6 ? 30.957 -181.697 54.404 1.00 67.26 ? 1263 ILE B CG1 1 ATOM 9255 C CG2 . ILE D 2 6 ? 31.813 -179.705 55.649 1.00 54.92 ? 1263 ILE B CG2 1 ATOM 9256 C CD1 . ILE D 2 6 ? 30.343 -182.488 55.545 1.00 77.66 ? 1263 ILE B CD1 1 ATOM 9257 N N . THR D 2 7 ? 34.917 -179.360 54.394 1.00 56.83 ? 1264 THR B N 1 ATOM 9258 C CA . THR D 2 7 ? 35.843 -178.258 54.630 1.00 59.85 ? 1264 THR B CA 1 ATOM 9259 C C . THR D 2 7 ? 36.252 -177.619 53.309 1.00 59.83 ? 1264 THR B C 1 ATOM 9260 O O . THR D 2 7 ? 36.200 -176.394 53.148 1.00 55.18 ? 1264 THR B O 1 ATOM 9261 C CB . THR D 2 7 ? 37.096 -178.750 55.401 1.00 55.60 ? 1264 THR B CB 1 ATOM 9262 O OG1 . THR D 2 7 ? 36.835 -178.705 56.808 1.00 62.32 ? 1264 THR B OG1 1 ATOM 9263 C CG2 . THR D 2 7 ? 38.336 -177.904 55.099 1.00 52.75 ? 1264 THR B CG2 1 ATOM 9264 N N . GLN D 2 8 ? 36.649 -178.461 52.362 1.00 54.80 ? 1265 GLN B N 1 ATOM 9265 C CA . GLN D 2 8 ? 37.043 -177.995 51.042 1.00 57.15 ? 1265 GLN B CA 1 ATOM 9266 C C . GLN D 2 8 ? 35.886 -177.254 50.379 1.00 42.64 ? 1265 GLN B C 1 ATOM 9267 O O . GLN D 2 8 ? 36.090 -176.217 49.755 1.00 35.37 ? 1265 GLN B O 1 ATOM 9268 C CB . GLN D 2 8 ? 37.502 -179.164 50.161 1.00 65.30 ? 1265 GLN B CB 1 ATOM 9269 C CG . GLN D 2 8 ? 38.205 -178.728 48.881 1.00 65.53 ? 1265 GLN B CG 1 ATOM 9270 C CD . GLN D 2 8 ? 39.389 -177.815 49.154 1.00 83.93 ? 1265 GLN B CD 1 ATOM 9271 O OE1 . GLN D 2 8 ? 40.092 -177.976 50.152 1.00 73.63 ? 1265 GLN B OE1 1 ATOM 9272 N NE2 . GLN D 2 8 ? 39.603 -176.840 48.278 1.00 79.45 ? 1265 GLN B NE2 1 ATOM 9273 N N . HIS D 2 9 ? 34.673 -177.784 50.527 1.00 36.28 ? 1266 HIS B N 1 ATOM 9274 C CA . HIS D 2 9 ? 33.479 -177.134 49.996 1.00 47.75 ? 1266 HIS B CA 1 ATOM 9275 C C . HIS D 2 9 ? 33.297 -175.761 50.632 1.00 43.41 ? 1266 HIS B C 1 ATOM 9276 O O . HIS D 2 9 ? 32.992 -174.788 49.942 1.00 36.79 ? 1266 HIS B O 1 ATOM 9277 C CB . HIS D 2 9 ? 32.226 -177.984 50.236 1.00 45.94 ? 1266 HIS B CB 1 ATOM 9278 C CG . HIS D 2 9 ? 30.972 -177.368 49.697 1.00 52.51 ? 1266 HIS B CG 1 ATOM 9279 N ND1 . HIS D 2 9 ? 30.750 -177.192 48.348 1.00 51.89 ? 1266 HIS B ND1 1 ATOM 9280 C CD2 . HIS D 2 9 ? 29.879 -176.873 50.325 1.00 51.69 ? 1266 HIS B CD2 1 ATOM 9281 C CE1 . HIS D 2 9 ? 29.572 -176.622 48.168 1.00 56.53 ? 1266 HIS B CE1 1 ATOM 9282 N NE2 . HIS D 2 9 ? 29.022 -176.418 49.352 1.00 58.58 ? 1266 HIS B NE2 1 ATOM 9283 N N . LEU D 2 10 ? 33.476 -175.687 51.948 1.00 43.49 ? 1267 LEU B N 1 ATOM 9284 C CA . LEU D 2 10 ? 33.396 -174.411 52.652 1.00 33.51 ? 1267 LEU B CA 1 ATOM 9285 C C . LEU D 2 10 ? 34.421 -173.423 52.116 1.00 35.32 ? 1267 LEU B C 1 ATOM 9286 O O . LEU D 2 10 ? 34.085 -172.270 51.840 1.00 29.00 ? 1267 LEU B O 1 ATOM 9287 C CB . LEU D 2 10 ? 33.595 -174.601 54.159 1.00 37.70 ? 1267 LEU B CB 1 ATOM 9288 C CG . LEU D 2 10 ? 32.427 -175.244 54.913 1.00 44.84 ? 1267 LEU B CG 1 ATOM 9289 C CD1 . LEU D 2 10 ? 32.830 -175.553 56.345 1.00 50.25 ? 1267 LEU B CD1 1 ATOM 9290 C CD2 . LEU D 2 10 ? 31.199 -174.345 54.889 1.00 37.32 ? 1267 LEU B CD2 1 ATOM 9291 N N . ASN D 2 11 ? 35.667 -173.861 51.971 1.00 29.21 ? 1268 ASN B N 1 ATOM 9292 C CA . ASN D 2 11 ? 36.687 -172.992 51.394 1.00 24.64 ? 1268 ASN B CA 1 ATOM 9293 C C . ASN D 2 11 ? 36.350 -172.568 49.964 1.00 38.64 ? 1268 ASN B C 1 ATOM 9294 O O . ASN D 2 11 ? 36.557 -171.416 49.588 1.00 28.80 ? 1268 ASN B O 1 ATOM 9295 C CB . ASN D 2 11 ? 38.056 -173.676 51.416 1.00 34.27 ? 1268 ASN B CB 1 ATOM 9296 C CG . ASN D 2 11 ? 39.147 -172.804 50.819 1.00 39.56 ? 1268 ASN B CG 1 ATOM 9297 O OD1 . ASN D 2 11 ? 39.444 -172.891 49.627 1.00 54.75 ? 1268 ASN B OD1 1 ATOM 9298 N ND2 . ASN D 2 11 ? 39.737 -171.945 51.643 1.00 44.29 ? 1268 ASN B ND2 1 ATOM 9299 N N . ASP D 2 12 ? 35.830 -173.501 49.171 1.00 31.28 ? 1269 ASP B N 1 ATOM 9300 C CA . ASP D 2 12 ? 35.442 -173.210 47.793 1.00 37.60 ? 1269 ASP B CA 1 ATOM 9301 C C . ASP D 2 12 ? 34.263 -172.242 47.724 1.00 32.55 ? 1269 ASP B C 1 ATOM 9302 O O . ASP D 2 12 ? 34.099 -171.525 46.738 1.00 31.08 ? 1269 ASP B O 1 ATOM 9303 C CB . ASP D 2 12 ? 35.092 -174.507 47.054 1.00 35.88 ? 1269 ASP B CB 1 ATOM 9304 C CG . ASP D 2 12 ? 36.298 -175.409 46.854 1.00 43.78 ? 1269 ASP B CG 1 ATOM 9305 O OD1 . ASP D 2 12 ? 37.440 -174.901 46.896 1.00 50.54 ? 1269 ASP B OD1 1 ATOM 9306 O OD2 . ASP D 2 12 ? 36.105 -176.626 46.650 1.00 51.74 ? 1269 ASP B OD2 1 ATOM 9307 N N . SER D 2 13 ? 33.449 -172.224 48.775 1.00 28.37 ? 1270 SER B N 1 ATOM 9308 C CA . SER D 2 13 ? 32.267 -171.366 48.823 1.00 28.29 ? 1270 SER B CA 1 ATOM 9309 C C . SER D 2 13 ? 32.585 -169.965 49.349 1.00 23.58 ? 1270 SER B C 1 ATOM 9310 O O . SER D 2 13 ? 31.704 -169.106 49.403 1.00 22.55 ? 1270 SER B O 1 ATOM 9311 C CB . SER D 2 13 ? 31.186 -172.010 49.691 1.00 28.71 ? 1270 SER B CB 1 ATOM 9312 O OG . SER D 2 13 ? 30.719 -173.217 49.112 1.00 38.17 ? 1270 SER B OG 1 ATOM 9313 N N . GLY D 2 14 ? 33.837 -169.745 49.744 1.00 23.59 ? 1271 GLY B N 1 ATOM 9314 C CA . GLY D 2 14 ? 34.301 -168.427 50.142 1.00 25.81 ? 1271 GLY B CA 1 ATOM 9315 C C . GLY D 2 14 ? 34.522 -168.228 51.634 1.00 27.45 ? 1271 GLY B C 1 ATOM 9316 O O . GLY D 2 14 ? 34.681 -167.092 52.080 1.00 22.50 ? 1271 GLY B O 1 ATOM 9317 N N . LEU D 2 15 ? 34.535 -169.311 52.408 1.00 24.66 ? 1272 LEU B N 1 ATOM 9318 C CA . LEU D 2 15 ? 34.809 -169.211 53.843 1.00 29.84 ? 1272 LEU B CA 1 ATOM 9319 C C . LEU D 2 15 ? 36.149 -168.516 54.061 1.00 24.75 ? 1272 LEU B C 1 ATOM 9320 O O . LEU D 2 15 ? 37.167 -168.920 53.499 1.00 32.08 ? 1272 LEU B O 1 ATOM 9321 C CB . LEU D 2 15 ? 34.814 -170.592 54.504 1.00 35.47 ? 1272 LEU B CB 1 ATOM 9322 C CG . LEU D 2 15 ? 35.038 -170.613 56.022 1.00 51.37 ? 1272 LEU B CG 1 ATOM 9323 C CD1 . LEU D 2 15 ? 33.770 -170.229 56.771 1.00 37.28 ? 1272 LEU B CD1 1 ATOM 9324 C CD2 . LEU D 2 15 ? 35.539 -171.976 56.477 1.00 37.47 ? 1272 LEU B CD2 1 ATOM 9325 N N . GLY D 2 16 ? 36.141 -167.466 54.877 1.00 29.41 ? 1273 GLY B N 1 ATOM 9326 C CA . GLY D 2 16 ? 37.305 -166.615 55.033 1.00 30.66 ? 1273 GLY B CA 1 ATOM 9327 C C . GLY D 2 16 ? 38.285 -167.089 56.087 1.00 31.57 ? 1273 GLY B C 1 ATOM 9328 O O . GLY D 2 16 ? 38.014 -168.051 56.807 1.00 27.67 ? 1273 GLY B O 1 ATOM 9329 N N . PRO D 2 17 ? 39.439 -166.412 56.178 1.00 32.06 ? 1274 PRO B N 1 ATOM 9330 C CA . PRO D 2 17 ? 40.471 -166.730 57.171 1.00 33.57 ? 1274 PRO B CA 1 ATOM 9331 C C . PRO D 2 17 ? 40.080 -166.322 58.583 1.00 37.30 ? 1274 PRO B C 1 ATOM 9332 O O . PRO D 2 17 ? 39.379 -165.327 58.766 1.00 35.98 ? 1274 PRO B O 1 ATOM 9333 C CB . PRO D 2 17 ? 41.678 -165.916 56.696 1.00 33.89 ? 1274 PRO B CB 1 ATOM 9334 C CG . PRO D 2 17 ? 41.097 -164.785 55.929 1.00 31.35 ? 1274 PRO B CG 1 ATOM 9335 C CD . PRO D 2 17 ? 39.851 -165.314 55.285 1.00 30.73 ? 1274 PRO B CD 1 ATOM 9336 N N . ALA D 2 18 ? 40.531 -167.092 59.568 1.00 43.02 ? 1275 ALA B N 1 ATOM 9337 C CA . ALA D 2 18 ? 40.370 -166.714 60.965 1.00 51.58 ? 1275 ALA B CA 1 ATOM 9338 C C . ALA D 2 18 ? 41.331 -165.580 61.297 1.00 44.74 ? 1275 ALA B C 1 ATOM 9339 O O . ALA D 2 18 ? 42.529 -165.807 61.469 1.00 55.37 ? 1275 ALA B O 1 ATOM 9340 C CB . ALA D 2 18 ? 40.613 -167.903 61.873 1.00 55.17 ? 1275 ALA B CB 1 ATOM 9341 N N . VAL D 2 19 ? 40.799 -164.364 61.377 1.00 39.92 ? 1276 VAL B N 1 ATOM 9342 C CA . VAL D 2 19 ? 41.607 -163.188 61.677 1.00 47.27 ? 1276 VAL B CA 1 ATOM 9343 C C . VAL D 2 19 ? 41.199 -162.573 63.007 1.00 43.62 ? 1276 VAL B C 1 ATOM 9344 O O . VAL D 2 19 ? 40.029 -162.601 63.388 1.00 42.63 ? 1276 VAL B O 1 ATOM 9345 C CB . VAL D 2 19 ? 41.496 -162.119 60.571 1.00 38.54 ? 1276 VAL B CB 1 ATOM 9346 C CG1 . VAL D 2 19 ? 42.079 -162.648 59.275 1.00 49.47 ? 1276 VAL B CG1 1 ATOM 9347 C CG2 . VAL D 2 19 ? 40.049 -161.681 60.375 1.00 38.80 ? 1276 VAL B CG2 1 ATOM 9348 N N . GLU D 2 20 ? 42.186 -162.023 63.704 1.00 39.87 ? 1277 GLU B N 1 ATOM 9349 C CA . GLU D 2 20 ? 41.973 -161.393 64.999 1.00 48.83 ? 1277 GLU B CA 1 ATOM 9350 C C . GLU D 2 20 ? 41.780 -159.890 64.860 1.00 41.47 ? 1277 GLU B C 1 ATOM 9351 O O . GLU D 2 20 ? 41.169 -159.259 65.723 1.00 45.94 ? 1277 GLU B O 1 ATOM 9352 C CB . GLU D 2 20 ? 43.162 -161.682 65.925 1.00 54.87 ? 1277 GLU B CB 1 ATOM 9353 C CG . GLU D 2 20 ? 43.119 -160.972 67.282 1.00 86.46 ? 1277 GLU B CG 1 ATOM 9354 C CD . GLU D 2 20 ? 41.932 -161.389 68.131 1.00 87.24 ? 1277 GLU B CD 1 ATOM 9355 O OE1 . GLU D 2 20 ? 41.544 -162.574 68.071 1.00 76.11 ? 1277 GLU B OE1 1 ATOM 9356 O OE2 . GLU D 2 20 ? 41.388 -160.531 68.861 1.00 70.20 ? 1277 GLU B OE2 1 ATOM 9357 N N A CYS D 2 21 ? 42.283 -159.330 63.762 0.74 36.57 ? 1278 CYS B N 1 ATOM 9358 N N B CYS D 2 21 ? 42.298 -159.318 63.778 0.26 36.71 ? 1278 CYS B N 1 ATOM 9359 C CA A CYS D 2 21 ? 42.346 -157.883 63.595 0.74 35.54 ? 1278 CYS B CA 1 ATOM 9360 C CA B CYS D 2 21 ? 42.296 -157.870 63.616 0.26 35.63 ? 1278 CYS B CA 1 ATOM 9361 C C A CYS D 2 21 ? 42.123 -157.444 62.151 0.74 34.70 ? 1278 CYS B C 1 ATOM 9362 C C B CYS D 2 21 ? 42.130 -157.434 62.166 0.26 34.70 ? 1278 CYS B C 1 ATOM 9363 O O A CYS D 2 21 ? 42.608 -158.084 61.217 0.74 32.04 ? 1278 CYS B O 1 ATOM 9364 O O B CYS D 2 21 ? 42.652 -158.066 61.245 0.26 32.21 ? 1278 CYS B O 1 ATOM 9365 C CB A CYS D 2 21 ? 43.704 -157.368 64.077 0.74 42.50 ? 1278 CYS B CB 1 ATOM 9366 C CB B CYS D 2 21 ? 43.592 -157.281 64.177 0.26 42.36 ? 1278 CYS B CB 1 ATOM 9367 S SG A CYS D 2 21 ? 43.941 -155.586 63.899 0.74 47.62 ? 1278 CYS B SG 1 ATOM 9368 S SG B CYS D 2 21 ? 43.435 -156.531 65.812 0.26 47.56 ? 1278 CYS B SG 1 ATOM 9369 N N . LEU D 2 22 ? 41.389 -156.345 61.985 1.00 33.04 ? 1279 LEU B N 1 ATOM 9370 C CA . LEU D 2 22 ? 41.253 -155.686 60.688 1.00 28.88 ? 1279 LEU B CA 1 ATOM 9371 C C . LEU D 2 22 ? 41.839 -154.285 60.810 1.00 31.18 ? 1279 LEU B C 1 ATOM 9372 O O . LEU D 2 22 ? 41.719 -153.655 61.858 1.00 33.64 ? 1279 LEU B O 1 ATOM 9373 C CB . LEU D 2 22 ? 39.789 -155.623 60.238 1.00 28.39 ? 1279 LEU B CB 1 ATOM 9374 C CG . LEU D 2 22 ? 39.272 -156.725 59.307 1.00 33.84 ? 1279 LEU B CG 1 ATOM 9375 C CD1 . LEU D 2 22 ? 39.624 -158.111 59.810 1.00 35.45 ? 1279 LEU B CD1 1 ATOM 9376 C CD2 . LEU D 2 22 ? 37.768 -156.592 59.149 1.00 38.63 ? 1279 LEU B CD2 1 ATOM 9377 N N . GLU D 2 23 ? 42.479 -153.806 59.748 1.00 27.60 ? 1280 GLU B N 1 ATOM 9378 C CA . GLU D 2 23 ? 43.000 -152.442 59.713 1.00 32.17 ? 1280 GLU B CA 1 ATOM 9379 C C . GLU D 2 23 ? 42.136 -151.572 58.809 1.00 30.50 ? 1280 GLU B C 1 ATOM 9380 O O . GLU D 2 23 ? 41.967 -151.875 57.627 1.00 30.02 ? 1280 GLU B O 1 ATOM 9381 C CB . GLU D 2 23 ? 44.454 -152.424 59.228 1.00 33.11 ? 1280 GLU B CB 1 ATOM 9382 C CG . GLU D 2 23 ? 45.065 -151.027 59.115 1.00 48.09 ? 1280 GLU B CG 1 ATOM 9383 C CD . GLU D 2 23 ? 45.096 -150.286 60.440 1.00 61.86 ? 1280 GLU B CD 1 ATOM 9384 O OE1 . GLU D 2 23 ? 45.066 -150.950 61.497 1.00 69.02 ? 1280 GLU B OE1 1 ATOM 9385 O OE2 . GLU D 2 23 ? 45.150 -149.037 60.424 1.00 60.16 ? 1280 GLU B OE2 1 ATOM 9386 N N . ASN D 2 24 ? 41.585 -150.501 59.373 1.00 24.47 ? 1281 ASN B N 1 ATOM 9387 C CA . ASN D 2 24 ? 40.801 -149.545 58.603 1.00 28.88 ? 1281 ASN B CA 1 ATOM 9388 C C . ASN D 2 24 ? 41.431 -148.159 58.660 1.00 33.99 ? 1281 ASN B C 1 ATOM 9389 O O . ASN D 2 24 ? 41.832 -147.695 59.726 1.00 33.80 ? 1281 ASN B O 1 ATOM 9390 C CB . ASN D 2 24 ? 39.365 -149.499 59.118 1.00 25.98 ? 1281 ASN B CB 1 ATOM 9391 C CG . ASN D 2 24 ? 38.534 -148.448 58.421 1.00 31.22 ? 1281 ASN B CG 1 ATOM 9392 O OD1 . ASN D 2 24 ? 38.541 -147.281 58.806 1.00 32.48 ? 1281 ASN B OD1 1 ATOM 9393 N ND2 . ASN D 2 24 ? 37.812 -148.856 57.385 1.00 28.18 ? 1281 ASN B ND2 1 ATOM 9394 N N . LEU D 2 25 ? 41.556 -147.524 57.511 1.00 28.27 ? 1282 LEU B N 1 ATOM 9395 C CA . LEU D 2 25 ? 42.187 -146.217 57.401 1.00 30.27 ? 1282 LEU B CA 1 ATOM 9396 C C . LEU D 2 25 ? 41.469 -145.081 58.097 1.00 28.68 ? 1282 LEU B C 1 ATOM 9397 O O . LEU D 2 25 ? 42.065 -144.076 58.420 1.00 42.42 ? 1282 LEU B O 1 ATOM 9398 C CB . LEU D 2 25 ? 42.474 -145.866 55.944 1.00 34.97 ? 1282 LEU B CB 1 ATOM 9399 C CG . LEU D 2 25 ? 43.229 -146.935 55.160 1.00 46.61 ? 1282 LEU B CG 1 ATOM 9400 C CD1 . LEU D 2 25 ? 43.583 -146.488 53.757 1.00 42.39 ? 1282 LEU B CD1 1 ATOM 9401 C CD2 . LEU D 2 25 ? 44.456 -147.413 55.907 1.00 41.01 ? 1282 LEU B CD2 1 ATOM 9402 N N . VAL D 2 26 ? 40.180 -145.230 58.301 1.00 29.85 ? 1283 VAL B N 1 ATOM 9403 C CA . VAL D 2 26 ? 39.389 -144.172 58.924 1.00 32.28 ? 1283 VAL B CA 1 ATOM 9404 C C . VAL D 2 26 ? 39.405 -144.278 60.452 1.00 33.39 ? 1283 VAL B C 1 ATOM 9405 O O . VAL D 2 26 ? 39.531 -143.265 61.142 1.00 34.90 ? 1283 VAL B O 1 ATOM 9406 C CB . VAL D 2 26 ? 37.927 -144.197 58.428 1.00 35.90 ? 1283 VAL B CB 1 ATOM 9407 C CG1 . VAL D 2 26 ? 37.094 -143.144 59.145 1.00 38.04 ? 1283 VAL B CG1 1 ATOM 9408 C CG2 . VAL D 2 26 ? 37.878 -143.965 56.927 1.00 37.97 ? 1283 VAL B CG2 1 ATOM 9409 N N . VAL D 2 27 ? 39.286 -145.500 60.971 1.00 28.51 ? 1284 VAL B N 1 ATOM 9410 C CA . VAL D 2 27 ? 39.144 -145.723 62.411 1.00 30.70 ? 1284 VAL B CA 1 ATOM 9411 C C . VAL D 2 27 ? 40.308 -146.509 63.016 1.00 27.86 ? 1284 VAL B C 1 ATOM 9412 O O . VAL D 2 27 ? 40.318 -146.784 64.216 1.00 29.13 ? 1284 VAL B O 1 ATOM 9413 C CB . VAL D 2 27 ? 37.827 -146.470 62.731 1.00 30.33 ? 1284 VAL B CB 1 ATOM 9414 C CG1 . VAL D 2 27 ? 36.638 -145.697 62.180 1.00 36.45 ? 1284 VAL B CG1 1 ATOM 9415 C CG2 . VAL D 2 27 ? 37.842 -147.894 62.173 1.00 29.18 ? 1284 VAL B CG2 1 ATOM 9416 N N . GLY D 2 28 ? 41.283 -146.873 62.189 1.00 28.85 ? 1285 GLY B N 1 ATOM 9417 C CA . GLY D 2 28 ? 42.439 -147.614 62.660 1.00 24.87 ? 1285 GLY B CA 1 ATOM 9418 C C . GLY D 2 28 ? 42.172 -149.105 62.765 1.00 31.86 ? 1285 GLY B C 1 ATOM 9419 O O . GLY D 2 28 ? 41.295 -149.631 62.078 1.00 37.41 ? 1285 GLY B O 1 ATOM 9420 N N . PRO D 2 29 ? 42.948 -149.803 63.610 1.00 29.81 ? 1286 PRO B N 1 ATOM 9421 C CA . PRO D 2 29 ? 42.734 -151.237 63.821 1.00 22.03 ? 1286 PRO B CA 1 ATOM 9422 C C . PRO D 2 29 ? 41.477 -151.541 64.628 1.00 32.15 ? 1286 PRO B C 1 ATOM 9423 O O . PRO D 2 29 ? 41.137 -150.802 65.553 1.00 24.85 ? 1286 PRO B O 1 ATOM 9424 C CB . PRO D 2 29 ? 43.988 -151.675 64.586 1.00 34.14 ? 1286 PRO B CB 1 ATOM 9425 C CG . PRO D 2 29 ? 44.508 -150.438 65.210 1.00 34.76 ? 1286 PRO B CG 1 ATOM 9426 C CD . PRO D 2 29 ? 44.182 -149.333 64.262 1.00 30.44 ? 1286 PRO B CD 1 ATOM 9427 N N . VAL D 2 30 ? 40.800 -152.627 64.268 1.00 26.63 ? 1287 VAL B N 1 ATOM 9428 C CA . VAL D 2 30 ? 39.611 -153.067 64.978 1.00 20.38 ? 1287 VAL B CA 1 ATOM 9429 C C . VAL D 2 30 ? 39.679 -154.568 65.226 1.00 24.55 ? 1287 VAL B C 1 ATOM 9430 O O . VAL D 2 30 ? 40.170 -155.335 64.388 1.00 26.97 ? 1287 VAL B O 1 ATOM 9431 C CB . VAL D 2 30 ? 38.319 -152.721 64.210 1.00 20.76 ? 1287 VAL B CB 1 ATOM 9432 C CG1 . VAL D 2 30 ? 38.127 -151.214 64.161 1.00 24.71 ? 1287 VAL B CG1 1 ATOM 9433 C CG2 . VAL D 2 30 ? 38.343 -153.310 62.803 1.00 30.65 ? 1287 VAL B CG2 1 ATOM 9434 N N . CYS D 2 31 ? 39.187 -154.961 66.397 1.00 25.77 ? 1288 CYS B N 1 ATOM 9435 C CA . CYS D 2 31 ? 39.215 -156.343 66.853 1.00 30.70 ? 1288 CYS B CA 1 ATOM 9436 C C . CYS D 2 31 ? 37.893 -156.706 67.510 1.00 22.86 ? 1288 CYS B C 1 ATOM 9437 O O . CYS D 2 31 ? 37.173 -155.827 67.980 1.00 22.36 ? 1288 CYS B O 1 ATOM 9438 C CB . CYS D 2 31 ? 40.355 -156.553 67.851 1.00 38.93 ? 1288 CYS B CB 1 ATOM 9439 S SG . CYS D 2 31 ? 41.981 -156.218 67.196 1.00 48.61 ? 1288 CYS B SG 1 ATOM 9440 N N . PRO D 2 32 ? 37.571 -158.006 67.560 1.00 25.94 ? 1289 PRO B N 1 ATOM 9441 C CA . PRO D 2 32 ? 36.352 -158.402 68.268 1.00 31.97 ? 1289 PRO B CA 1 ATOM 9442 C C . PRO D 2 32 ? 36.542 -158.340 69.781 1.00 34.53 ? 1289 PRO B C 1 ATOM 9443 O O . PRO D 2 32 ? 37.575 -158.782 70.283 1.00 31.03 ? 1289 PRO B O 1 ATOM 9444 C CB . PRO D 2 32 ? 36.124 -159.834 67.791 1.00 30.03 ? 1289 PRO B CB 1 ATOM 9445 C CG . PRO D 2 32 ? 37.497 -160.349 67.505 1.00 31.73 ? 1289 PRO B CG 1 ATOM 9446 C CD . PRO D 2 32 ? 38.293 -159.167 67.008 1.00 28.95 ? 1289 PRO B CD 1 ATOM 9447 N N . ALA D 2 33 ? 35.563 -157.790 70.491 1.00 25.43 ? 1290 ALA B N 1 ATOM 9448 C CA . ALA D 2 33 ? 35.652 -157.651 71.940 1.00 33.09 ? 1290 ALA B CA 1 ATOM 9449 C C . ALA D 2 33 ? 35.517 -159.011 72.619 1.00 35.97 ? 1290 ALA B C 1 ATOM 9450 O O . ALA D 2 33 ? 36.077 -159.238 73.692 1.00 40.51 ? 1290 ALA B O 1 ATOM 9451 C CB . ALA D 2 33 ? 34.584 -156.695 72.444 1.00 29.33 ? 1290 ALA B CB 1 ATOM 9452 N N . ALA D 2 34 ? 34.767 -159.907 71.983 1.00 38.18 ? 1291 ALA B N 1 ATOM 9453 C CA . ALA D 2 34 ? 34.603 -161.275 72.462 1.00 38.16 ? 1291 ALA B CA 1 ATOM 9454 C C . ALA D 2 34 ? 34.949 -162.255 71.349 1.00 38.84 ? 1291 ALA B C 1 ATOM 9455 O O . ALA D 2 34 ? 34.864 -161.917 70.169 1.00 36.16 ? 1291 ALA B O 1 ATOM 9456 C CB . ALA D 2 34 ? 33.184 -161.503 72.954 1.00 34.71 ? 1291 ALA B CB 1 ATOM 9457 N N . VAL D 2 35 ? 35.338 -163.467 71.726 1.00 35.57 ? 1292 VAL B N 1 ATOM 9458 C CA . VAL D 2 35 ? 35.734 -164.475 70.751 1.00 37.36 ? 1292 VAL B CA 1 ATOM 9459 C C . VAL D 2 35 ? 34.583 -164.773 69.796 1.00 30.39 ? 1292 VAL B C 1 ATOM 9460 O O . VAL D 2 35 ? 33.473 -165.094 70.222 1.00 24.27 ? 1292 VAL B O 1 ATOM 9461 C CB . VAL D 2 35 ? 36.184 -165.785 71.434 1.00 43.88 ? 1292 VAL B CB 1 ATOM 9462 C CG1 . VAL D 2 35 ? 36.630 -166.810 70.392 1.00 46.72 ? 1292 VAL B CG1 1 ATOM 9463 C CG2 . VAL D 2 35 ? 37.310 -165.513 72.423 1.00 46.87 ? 1292 VAL B CG2 1 ATOM 9464 N N . VAL D 2 36 ? 34.856 -164.647 68.501 1.00 36.75 ? 1293 VAL B N 1 ATOM 9465 C CA . VAL D 2 36 ? 33.882 -164.978 67.469 1.00 33.02 ? 1293 VAL B CA 1 ATOM 9466 C C . VAL D 2 36 ? 33.764 -166.493 67.357 1.00 35.69 ? 1293 VAL B C 1 ATOM 9467 O O . VAL D 2 36 ? 34.744 -167.211 67.554 1.00 31.44 ? 1293 VAL B O 1 ATOM 9468 C CB . VAL D 2 36 ? 34.285 -164.379 66.099 1.00 33.56 ? 1293 VAL B CB 1 ATOM 9469 C CG1 . VAL D 2 36 ? 33.284 -164.763 65.010 1.00 30.77 ? 1293 VAL B CG1 1 ATOM 9470 C CG2 . VAL D 2 36 ? 34.401 -162.868 66.195 1.00 45.28 ? 1293 VAL B CG2 1 ATOM 9471 N N . ALA D 2 37 ? 32.565 -166.977 67.051 1.00 27.51 ? 1294 ALA B N 1 ATOM 9472 C CA . ALA D 2 37 ? 32.368 -168.400 66.807 1.00 31.01 ? 1294 ALA B CA 1 ATOM 9473 C C . ALA D 2 37 ? 33.315 -168.850 65.691 1.00 33.91 ? 1294 ALA B C 1 ATOM 9474 O O . ALA D 2 37 ? 33.209 -168.362 64.569 1.00 31.93 ? 1294 ALA B O 1 ATOM 9475 C CB . ALA D 2 37 ? 30.927 -168.683 66.440 1.00 31.59 ? 1294 ALA B CB 1 ATOM 9476 N N . PRO D 2 38 ? 34.260 -169.763 65.997 1.00 39.87 ? 1295 PRO B N 1 ATOM 9477 C CA . PRO D 2 38 ? 35.283 -170.142 65.010 1.00 47.65 ? 1295 PRO B CA 1 ATOM 9478 C C . PRO D 2 38 ? 34.737 -170.699 63.693 1.00 34.37 ? 1295 PRO B C 1 ATOM 9479 O O . PRO D 2 38 ? 35.426 -170.628 62.676 1.00 35.61 ? 1295 PRO B O 1 ATOM 9480 C CB . PRO D 2 38 ? 36.090 -171.222 65.741 1.00 41.99 ? 1295 PRO B CB 1 ATOM 9481 C CG . PRO D 2 38 ? 35.891 -170.939 67.173 1.00 47.98 ? 1295 PRO B CG 1 ATOM 9482 C CD . PRO D 2 38 ? 34.492 -170.427 67.294 1.00 35.90 ? 1295 PRO B CD 1 ATOM 9483 N N . ALA D 2 39 ? 33.526 -171.246 63.711 1.00 36.04 ? 1296 ALA B N 1 ATOM 9484 C CA . ALA D 2 39 ? 32.946 -171.834 62.507 1.00 39.64 ? 1296 ALA B CA 1 ATOM 9485 C C . ALA D 2 39 ? 32.549 -170.760 61.492 1.00 45.08 ? 1296 ALA B C 1 ATOM 9486 O O . ALA D 2 39 ? 32.404 -171.045 60.304 1.00 42.76 ? 1296 ALA B O 1 ATOM 9487 C CB . ALA D 2 39 ? 31.745 -172.688 62.865 1.00 36.14 ? 1296 ALA B CB 1 ATOM 9488 N N . VAL D 2 40 ? 32.374 -169.529 61.964 1.00 47.49 ? 1297 VAL B N 1 ATOM 9489 C CA . VAL D 2 40 ? 31.975 -168.421 61.099 1.00 41.17 ? 1297 VAL B CA 1 ATOM 9490 C C . VAL D 2 40 ? 33.097 -168.034 60.138 1.00 39.28 ? 1297 VAL B C 1 ATOM 9491 O O . VAL D 2 40 ? 34.276 -168.247 60.420 1.00 51.69 ? 1297 VAL B O 1 ATOM 9492 C CB . VAL D 2 40 ? 31.564 -167.186 61.931 1.00 48.67 ? 1297 VAL B CB 1 ATOM 9493 C CG1 . VAL D 2 40 ? 31.194 -166.017 61.024 1.00 40.47 ? 1297 VAL B CG1 1 ATOM 9494 C CG2 . VAL D 2 40 ? 30.399 -167.532 62.852 1.00 41.80 ? 1297 VAL B CG2 1 ATOM 9495 N N . SER E 2 2 ? 31.038 -108.755 5.446 1.00 53.18 ? 1259 SER D N 1 ATOM 9496 C CA . SER E 2 2 ? 30.796 -109.873 6.339 1.00 89.52 ? 1259 SER D CA 1 ATOM 9497 C C . SER E 2 2 ? 31.980 -110.149 7.245 1.00 92.36 ? 1259 SER D C 1 ATOM 9498 O O . SER E 2 2 ? 31.827 -110.719 8.316 1.00 82.72 ? 1259 SER D O 1 ATOM 9499 C CB . SER E 2 2 ? 30.455 -111.129 5.558 1.00 81.89 ? 1259 SER D CB 1 ATOM 9500 O OG . SER E 2 2 ? 30.489 -112.248 6.416 1.00 80.74 ? 1259 SER D OG 1 ATOM 9501 N N . ALA E 2 3 ? 33.163 -109.745 6.811 1.00 88.90 ? 1260 ALA D N 1 ATOM 9502 C CA . ALA E 2 3 ? 34.344 -109.938 7.620 1.00 82.65 ? 1260 ALA D CA 1 ATOM 9503 C C . ALA E 2 3 ? 34.364 -108.765 8.559 1.00 80.41 ? 1260 ALA D C 1 ATOM 9504 O O . ALA E 2 3 ? 34.880 -108.851 9.662 1.00 69.61 ? 1260 ALA D O 1 ATOM 9505 C CB . ALA E 2 3 ? 35.593 -109.957 6.767 1.00 69.21 ? 1260 ALA D CB 1 ATOM 9506 N N . SER E 2 4 ? 33.787 -107.662 8.103 1.00 76.34 ? 1261 SER D N 1 ATOM 9507 C CA . SER E 2 4 ? 33.703 -106.459 8.921 1.00 76.08 ? 1261 SER D CA 1 ATOM 9508 C C . SER E 2 4 ? 32.700 -106.653 10.054 1.00 73.22 ? 1261 SER D C 1 ATOM 9509 O O . SER E 2 4 ? 32.870 -106.111 11.146 1.00 72.26 ? 1261 SER D O 1 ATOM 9510 C CB . SER E 2 4 ? 33.306 -105.258 8.059 1.00 76.05 ? 1261 SER D CB 1 ATOM 9511 O OG . SER E 2 4 ? 32.983 -104.132 8.856 1.00 79.87 ? 1261 SER D OG 1 ATOM 9512 N N . ASP E 2 5 ? 31.658 -107.434 9.785 1.00 74.59 ? 1262 ASP D N 1 ATOM 9513 C CA . ASP E 2 5 ? 30.627 -107.713 10.777 1.00 71.99 ? 1262 ASP D CA 1 ATOM 9514 C C . ASP E 2 5 ? 31.199 -108.485 11.962 1.00 59.55 ? 1262 ASP D C 1 ATOM 9515 O O . ASP E 2 5 ? 30.794 -108.273 13.105 1.00 52.93 ? 1262 ASP D O 1 ATOM 9516 C CB . ASP E 2 5 ? 29.476 -108.500 10.142 1.00 84.23 ? 1262 ASP D CB 1 ATOM 9517 C CG . ASP E 2 5 ? 28.611 -107.642 9.236 1.00 97.71 ? 1262 ASP D CG 1 ATOM 9518 O OD1 . ASP E 2 5 ? 28.279 -106.503 9.627 1.00 93.35 ? 1262 ASP D OD1 1 ATOM 9519 O OD2 . ASP E 2 5 ? 28.263 -108.106 8.130 1.00 94.91 ? 1262 ASP D OD2 1 ATOM 9520 N N . ILE E 2 6 ? 32.145 -109.377 11.683 1.00 50.36 ? 1263 ILE D N 1 ATOM 9521 C CA . ILE E 2 6 ? 32.779 -110.178 12.726 1.00 52.08 ? 1263 ILE D CA 1 ATOM 9522 C C . ILE E 2 6 ? 33.690 -109.312 13.594 1.00 52.94 ? 1263 ILE D C 1 ATOM 9523 O O . ILE E 2 6 ? 33.680 -109.425 14.821 1.00 44.34 ? 1263 ILE D O 1 ATOM 9524 C CB . ILE E 2 6 ? 33.578 -111.355 12.117 1.00 44.64 ? 1263 ILE D CB 1 ATOM 9525 C CG1 . ILE E 2 6 ? 32.599 -112.382 11.531 1.00 56.28 ? 1263 ILE D CG1 1 ATOM 9526 C CG2 . ILE E 2 6 ? 34.491 -112.007 13.166 1.00 43.35 ? 1263 ILE D CG2 1 ATOM 9527 C CD1 . ILE E 2 6 ? 33.239 -113.633 10.945 1.00 65.20 ? 1263 ILE D CD1 1 ATOM 9528 N N . THR E 2 7 ? 34.477 -108.453 12.954 1.00 50.55 ? 1264 THR D N 1 ATOM 9529 C CA . THR E 2 7 ? 35.317 -107.497 13.669 1.00 44.69 ? 1264 THR D CA 1 ATOM 9530 C C . THR E 2 7 ? 34.446 -106.596 14.536 1.00 40.82 ? 1264 THR D C 1 ATOM 9531 O O . THR E 2 7 ? 34.712 -106.404 15.729 1.00 43.51 ? 1264 THR D O 1 ATOM 9532 C CB . THR E 2 7 ? 36.146 -106.639 12.689 1.00 55.85 ? 1264 THR D CB 1 ATOM 9533 O OG1 . THR E 2 7 ? 37.043 -107.484 11.959 1.00 59.93 ? 1264 THR D OG1 1 ATOM 9534 C CG2 . THR E 2 7 ? 36.952 -105.574 13.425 1.00 41.00 ? 1264 THR D CG2 1 ATOM 9535 N N . GLN E 2 8 ? 33.397 -106.054 13.926 1.00 35.58 ? 1265 GLN D N 1 ATOM 9536 C CA . GLN E 2 8 ? 32.452 -105.201 14.631 1.00 43.42 ? 1265 GLN D CA 1 ATOM 9537 C C . GLN E 2 8 ? 31.836 -105.950 15.807 1.00 40.35 ? 1265 GLN D C 1 ATOM 9538 O O . GLN E 2 8 ? 31.716 -105.403 16.902 1.00 29.89 ? 1265 GLN D O 1 ATOM 9539 C CB . GLN E 2 8 ? 31.356 -104.710 13.681 1.00 41.26 ? 1265 GLN D CB 1 ATOM 9540 C CG . GLN E 2 8 ? 30.425 -103.671 14.288 1.00 48.72 ? 1265 GLN D CG 1 ATOM 9541 C CD . GLN E 2 8 ? 31.169 -102.451 14.797 1.00 76.43 ? 1265 GLN D CD 1 ATOM 9542 O OE1 . GLN E 2 8 ? 31.479 -101.535 14.035 1.00 71.01 ? 1265 GLN D OE1 1 ATOM 9543 N NE2 . GLN E 2 8 ? 31.466 -102.436 16.093 1.00 65.84 ? 1265 GLN D NE2 1 ATOM 9544 N N . HIS E 2 9 ? 31.454 -107.203 15.579 1.00 31.39 ? 1266 HIS D N 1 ATOM 9545 C CA . HIS E 2 9 ? 30.878 -108.026 16.636 1.00 37.04 ? 1266 HIS D CA 1 ATOM 9546 C C . HIS E 2 9 ? 31.874 -108.219 17.773 1.00 33.15 ? 1266 HIS D C 1 ATOM 9547 O O . HIS E 2 9 ? 31.515 -108.116 18.945 1.00 27.41 ? 1266 HIS D O 1 ATOM 9548 C CB . HIS E 2 9 ? 30.440 -109.388 16.097 1.00 30.91 ? 1266 HIS D CB 1 ATOM 9549 C CG . HIS E 2 9 ? 29.853 -110.285 17.143 1.00 46.60 ? 1266 HIS D CG 1 ATOM 9550 N ND1 . HIS E 2 9 ? 28.642 -110.027 17.748 1.00 39.44 ? 1266 HIS D ND1 1 ATOM 9551 C CD2 . HIS E 2 9 ? 30.317 -111.428 17.701 1.00 39.51 ? 1266 HIS D CD2 1 ATOM 9552 C CE1 . HIS E 2 9 ? 28.381 -110.977 18.628 1.00 39.05 ? 1266 HIS D CE1 1 ATOM 9553 N NE2 . HIS E 2 9 ? 29.382 -111.839 18.619 1.00 45.27 ? 1266 HIS D NE2 1 ATOM 9554 N N . LEU E 2 10 ? 33.124 -108.507 17.425 1.00 31.94 ? 1267 LEU D N 1 ATOM 9555 C CA . LEU E 2 10 ? 34.170 -108.640 18.430 1.00 30.64 ? 1267 LEU D CA 1 ATOM 9556 C C . LEU E 2 10 ? 34.311 -107.352 19.228 1.00 28.72 ? 1267 LEU D C 1 ATOM 9557 O O . LEU E 2 10 ? 34.408 -107.390 20.457 1.00 23.94 ? 1267 LEU D O 1 ATOM 9558 C CB . LEU E 2 10 ? 35.508 -109.007 17.785 1.00 33.33 ? 1267 LEU D CB 1 ATOM 9559 C CG . LEU E 2 10 ? 35.726 -110.491 17.473 1.00 31.55 ? 1267 LEU D CG 1 ATOM 9560 C CD1 . LEU E 2 10 ? 37.033 -110.694 16.720 1.00 37.01 ? 1267 LEU D CD1 1 ATOM 9561 C CD2 . LEU E 2 10 ? 35.722 -111.323 18.746 1.00 37.15 ? 1267 LEU D CD2 1 ATOM 9562 N N . ASN E 2 11 ? 34.314 -106.212 18.540 1.00 22.95 ? 1268 ASN D N 1 ATOM 9563 C CA . ASN E 2 11 ? 34.364 -104.929 19.239 1.00 17.61 ? 1268 ASN D CA 1 ATOM 9564 C C . ASN E 2 11 ? 33.150 -104.713 20.139 1.00 35.46 ? 1268 ASN D C 1 ATOM 9565 O O . ASN E 2 11 ? 33.279 -104.208 21.253 1.00 24.66 ? 1268 ASN D O 1 ATOM 9566 C CB . ASN E 2 11 ? 34.471 -103.762 18.252 1.00 32.53 ? 1268 ASN D CB 1 ATOM 9567 C CG . ASN E 2 11 ? 34.730 -102.432 18.951 1.00 53.66 ? 1268 ASN D CG 1 ATOM 9568 O OD1 . ASN E 2 11 ? 35.875 -102.086 19.241 1.00 44.33 ? 1268 ASN D OD1 1 ATOM 9569 N ND2 . ASN E 2 11 ? 33.664 -101.689 19.236 1.00 41.66 ? 1268 ASN D ND2 1 ATOM 9570 N N . ASP E 2 12 ? 31.971 -105.088 19.653 1.00 27.01 ? 1269 ASP D N 1 ATOM 9571 C CA . ASP E 2 12 ? 30.743 -104.936 20.428 1.00 27.89 ? 1269 ASP D CA 1 ATOM 9572 C C . ASP E 2 12 ? 30.726 -105.857 21.644 1.00 14.99 ? 1269 ASP D C 1 ATOM 9573 O O . ASP E 2 12 ? 30.046 -105.577 22.629 1.00 19.74 ? 1269 ASP D O 1 ATOM 9574 C CB . ASP E 2 12 ? 29.517 -105.214 19.554 1.00 31.77 ? 1269 ASP D CB 1 ATOM 9575 C CG . ASP E 2 12 ? 29.345 -104.195 18.443 1.00 42.28 ? 1269 ASP D CG 1 ATOM 9576 O OD1 . ASP E 2 12 ? 29.745 -103.026 18.635 1.00 46.82 ? 1269 ASP D OD1 1 ATOM 9577 O OD2 . ASP E 2 12 ? 28.808 -104.563 17.377 1.00 45.45 ? 1269 ASP D OD2 1 ATOM 9578 N N . SER E 2 13 ? 31.471 -106.955 21.567 1.00 15.94 ? 1270 SER D N 1 ATOM 9579 C CA . SER E 2 13 ? 31.537 -107.920 22.660 1.00 20.94 ? 1270 SER D CA 1 ATOM 9580 C C . SER E 2 13 ? 32.620 -107.567 23.680 1.00 24.74 ? 1270 SER D C 1 ATOM 9581 O O . SER E 2 13 ? 32.795 -108.275 24.672 1.00 17.94 ? 1270 SER D O 1 ATOM 9582 C CB . SER E 2 13 ? 31.785 -109.325 22.108 1.00 23.59 ? 1270 SER D CB 1 ATOM 9583 O OG . SER E 2 13 ? 30.673 -109.777 21.356 1.00 38.15 ? 1270 SER D OG 1 ATOM 9584 N N . GLY E 2 14 ? 33.346 -106.480 23.426 1.00 24.79 ? 1271 GLY D N 1 ATOM 9585 C CA . GLY E 2 14 ? 34.317 -105.962 24.376 1.00 24.21 ? 1271 GLY D CA 1 ATOM 9586 C C . GLY E 2 14 ? 35.764 -106.316 24.087 1.00 25.63 ? 1271 GLY D C 1 ATOM 9587 O O . GLY E 2 14 ? 36.598 -106.300 24.991 1.00 23.71 ? 1271 GLY D O 1 ATOM 9588 N N . LEU E 2 15 ? 36.078 -106.635 22.836 1.00 22.96 ? 1272 LEU D N 1 ATOM 9589 C CA . LEU E 2 15 ? 37.468 -106.850 22.456 1.00 27.62 ? 1272 LEU D CA 1 ATOM 9590 C C . LEU E 2 15 ? 38.234 -105.548 22.666 1.00 24.64 ? 1272 LEU D C 1 ATOM 9591 O O . LEU E 2 15 ? 37.814 -104.492 22.193 1.00 22.26 ? 1272 LEU D O 1 ATOM 9592 C CB . LEU E 2 15 ? 37.583 -107.317 21.005 1.00 29.27 ? 1272 LEU D CB 1 ATOM 9593 C CG . LEU E 2 15 ? 39.006 -107.644 20.542 1.00 35.16 ? 1272 LEU D CG 1 ATOM 9594 C CD1 . LEU E 2 15 ? 39.493 -108.942 21.167 1.00 28.72 ? 1272 LEU D CD1 1 ATOM 9595 C CD2 . LEU E 2 15 ? 39.085 -107.714 19.028 1.00 35.00 ? 1272 LEU D CD2 1 ATOM 9596 N N . GLY E 2 16 ? 39.349 -105.627 23.384 1.00 29.64 ? 1273 GLY D N 1 ATOM 9597 C CA . GLY E 2 16 ? 40.082 -104.440 23.786 1.00 34.53 ? 1273 GLY D CA 1 ATOM 9598 C C . GLY E 2 16 ? 41.133 -103.996 22.787 1.00 33.03 ? 1273 GLY D C 1 ATOM 9599 O O . GLY E 2 16 ? 41.426 -104.704 21.824 1.00 27.75 ? 1273 GLY D O 1 ATOM 9600 N N . PRO E 2 17 ? 41.714 -102.810 23.017 1.00 32.04 ? 1274 PRO D N 1 ATOM 9601 C CA . PRO E 2 17 ? 42.770 -102.282 22.149 1.00 34.96 ? 1274 PRO D CA 1 ATOM 9602 C C . PRO E 2 17 ? 44.052 -103.105 22.227 1.00 32.63 ? 1274 PRO D C 1 ATOM 9603 O O . PRO E 2 17 ? 44.328 -103.720 23.258 1.00 28.26 ? 1274 PRO D O 1 ATOM 9604 C CB . PRO E 2 17 ? 42.998 -100.867 22.692 1.00 36.33 ? 1274 PRO D CB 1 ATOM 9605 C CG . PRO E 2 17 ? 42.548 -100.926 24.109 1.00 35.50 ? 1274 PRO D CG 1 ATOM 9606 C CD . PRO E 2 17 ? 41.419 -101.909 24.145 1.00 32.25 ? 1274 PRO D CD 1 ATOM 9607 N N . ALA E 2 18 ? 44.816 -103.119 21.140 1.00 29.97 ? 1275 ALA D N 1 ATOM 9608 C CA . ALA E 2 18 ? 46.128 -103.752 21.137 1.00 40.68 ? 1275 ALA D CA 1 ATOM 9609 C C . ALA E 2 18 ? 47.131 -102.831 21.823 1.00 38.61 ? 1275 ALA D C 1 ATOM 9610 O O . ALA E 2 18 ? 47.728 -101.968 21.180 1.00 44.33 ? 1275 ALA D O 1 ATOM 9611 C CB . ALA E 2 18 ? 46.571 -104.065 19.714 1.00 41.82 ? 1275 ALA D CB 1 ATOM 9612 N N . VAL E 2 19 ? 47.301 -103.012 23.130 1.00 34.07 ? 1276 VAL D N 1 ATOM 9613 C CA . VAL E 2 19 ? 48.195 -102.160 23.906 1.00 45.28 ? 1276 VAL D CA 1 ATOM 9614 C C . VAL E 2 19 ? 49.509 -102.879 24.196 1.00 36.99 ? 1276 VAL D C 1 ATOM 9615 O O . VAL E 2 19 ? 49.529 -104.069 24.513 1.00 36.85 ? 1276 VAL D O 1 ATOM 9616 C CB . VAL E 2 19 ? 47.541 -101.707 25.233 1.00 37.83 ? 1276 VAL D CB 1 ATOM 9617 C CG1 . VAL E 2 19 ? 46.219 -101.007 24.951 1.00 44.27 ? 1276 VAL D CG1 1 ATOM 9618 C CG2 . VAL E 2 19 ? 47.329 -102.879 26.180 1.00 38.83 ? 1276 VAL D CG2 1 ATOM 9619 N N . GLU E 2 20 ? 50.603 -102.138 24.070 1.00 42.13 ? 1277 GLU D N 1 ATOM 9620 C CA . GLU E 2 20 ? 51.942 -102.667 24.293 1.00 38.38 ? 1277 GLU D CA 1 ATOM 9621 C C . GLU E 2 20 ? 52.295 -102.704 25.775 1.00 33.42 ? 1277 GLU D C 1 ATOM 9622 O O . GLU E 2 20 ? 52.998 -103.609 26.226 1.00 39.57 ? 1277 GLU D O 1 ATOM 9623 C CB . GLU E 2 20 ? 52.969 -101.814 23.532 1.00 47.76 ? 1277 GLU D CB 1 ATOM 9624 C CG . GLU E 2 20 ? 54.446 -102.128 23.809 1.00 76.67 ? 1277 GLU D CG 1 ATOM 9625 C CD . GLU E 2 20 ? 54.981 -103.240 22.934 1.00 83.76 ? 1277 GLU D CD 1 ATOM 9626 O OE1 . GLU E 2 20 ? 55.197 -102.993 21.728 1.00 71.96 ? 1277 GLU D OE1 1 ATOM 9627 O OE2 . GLU E 2 20 ? 55.193 -104.360 23.450 1.00 72.49 ? 1277 GLU D OE2 1 ATOM 9628 N N A CYS E 2 21 ? 51.822 -101.716 26.529 0.59 30.55 ? 1278 CYS D N 1 ATOM 9629 N N B CYS E 2 21 ? 51.791 -101.729 26.525 0.41 30.61 ? 1278 CYS D N 1 ATOM 9630 C CA A CYS E 2 21 ? 52.212 -101.581 27.929 0.59 32.75 ? 1278 CYS D CA 1 ATOM 9631 C CA B CYS E 2 21 ? 52.199 -101.547 27.912 0.41 32.71 ? 1278 CYS D CA 1 ATOM 9632 C C A CYS E 2 21 ? 51.106 -101.001 28.805 0.59 26.77 ? 1278 CYS D C 1 ATOM 9633 C C B CYS E 2 21 ? 51.092 -100.998 28.805 0.41 26.84 ? 1278 CYS D C 1 ATOM 9634 O O A CYS E 2 21 ? 50.259 -100.238 28.339 0.59 26.50 ? 1278 CYS D O 1 ATOM 9635 O O B CYS E 2 21 ? 50.227 -100.247 28.349 0.41 26.54 ? 1278 CYS D O 1 ATOM 9636 C CB A CYS E 2 21 ? 53.461 -100.702 28.045 0.59 33.13 ? 1278 CYS D CB 1 ATOM 9637 C CB B CYS E 2 21 ? 53.398 -100.604 27.974 0.41 33.05 ? 1278 CYS D CB 1 ATOM 9638 S SG A CYS E 2 21 ? 54.962 -101.411 27.320 0.59 37.70 ? 1278 CYS D SG 1 ATOM 9639 S SG B CYS E 2 21 ? 53.958 -100.225 29.655 0.41 40.13 ? 1278 CYS D SG 1 ATOM 9640 N N . LEU E 2 22 ? 51.137 -101.378 30.081 1.00 21.23 ? 1279 LEU D N 1 ATOM 9641 C CA . LEU E 2 22 ? 50.234 -100.828 31.096 1.00 27.66 ? 1279 LEU D CA 1 ATOM 9642 C C . LEU E 2 22 ? 51.047 -100.122 32.186 1.00 26.07 ? 1279 LEU D C 1 ATOM 9643 O O . LEU E 2 22 ? 52.158 -100.549 32.497 1.00 27.15 ? 1279 LEU D O 1 ATOM 9644 C CB . LEU E 2 22 ? 49.369 -101.930 31.723 1.00 25.63 ? 1279 LEU D CB 1 ATOM 9645 C CG . LEU E 2 22 ? 48.099 -102.410 31.011 1.00 30.37 ? 1279 LEU D CG 1 ATOM 9646 C CD1 . LEU E 2 22 ? 48.344 -102.777 29.566 1.00 35.76 ? 1279 LEU D CD1 1 ATOM 9647 C CD2 . LEU E 2 22 ? 47.544 -103.607 31.756 1.00 37.83 ? 1279 LEU D CD2 1 ATOM 9648 N N . GLU E 2 23 ? 50.498 -99.047 32.751 1.00 25.41 ? 1280 GLU D N 1 ATOM 9649 C CA . GLU E 2 23 ? 51.056 -98.428 33.956 1.00 29.15 ? 1280 GLU D CA 1 ATOM 9650 C C . GLU E 2 23 ? 50.359 -98.980 35.185 1.00 27.16 ? 1280 GLU D C 1 ATOM 9651 O O . GLU E 2 23 ? 49.131 -99.023 35.231 1.00 31.04 ? 1280 GLU D O 1 ATOM 9652 C CB . GLU E 2 23 ? 50.894 -96.901 33.951 1.00 28.25 ? 1280 GLU D CB 1 ATOM 9653 C CG . GLU E 2 23 ? 51.688 -96.159 32.903 1.00 50.53 ? 1280 GLU D CG 1 ATOM 9654 C CD . GLU E 2 23 ? 53.186 -96.170 33.164 1.00 56.49 ? 1280 GLU D CD 1 ATOM 9655 O OE1 . GLU E 2 23 ? 53.630 -96.840 34.120 1.00 55.25 ? 1280 GLU D OE1 1 ATOM 9656 O OE2 . GLU E 2 23 ? 53.922 -95.497 32.410 1.00 53.26 ? 1280 GLU D OE2 1 ATOM 9657 N N . ASN E 2 24 ? 51.142 -99.401 36.172 1.00 21.12 ? 1281 ASN D N 1 ATOM 9658 C CA . ASN E 2 24 ? 50.606 -99.774 37.474 1.00 26.70 ? 1281 ASN D CA 1 ATOM 9659 C C . ASN E 2 24 ? 51.349 -99.033 38.577 1.00 27.78 ? 1281 ASN D C 1 ATOM 9660 O O . ASN E 2 24 ? 52.578 -98.996 38.585 1.00 24.33 ? 1281 ASN D O 1 ATOM 9661 C CB . ASN E 2 24 ? 50.706 -101.282 37.688 1.00 21.45 ? 1281 ASN D CB 1 ATOM 9662 C CG . ASN E 2 24 ? 50.166 -101.711 39.033 1.00 33.48 ? 1281 ASN D CG 1 ATOM 9663 O OD1 . ASN E 2 24 ? 50.890 -101.731 40.026 1.00 29.51 ? 1281 ASN D OD1 1 ATOM 9664 N ND2 . ASN E 2 24 ? 48.883 -102.049 39.075 1.00 34.20 ? 1281 ASN D ND2 1 ATOM 9665 N N . LEU E 2 25 ? 50.605 -98.449 39.509 1.00 28.89 ? 1282 LEU D N 1 ATOM 9666 C CA . LEU E 2 25 ? 51.198 -97.571 40.515 1.00 35.12 ? 1282 LEU D CA 1 ATOM 9667 C C . LEU E 2 25 ? 52.056 -98.323 41.534 1.00 28.68 ? 1282 LEU D C 1 ATOM 9668 O O . LEU E 2 25 ? 52.900 -97.722 42.199 1.00 44.97 ? 1282 LEU D O 1 ATOM 9669 C CB . LEU E 2 25 ? 50.099 -96.795 41.244 1.00 34.07 ? 1282 LEU D CB 1 ATOM 9670 C CG . LEU E 2 25 ? 50.464 -95.382 41.704 1.00 50.86 ? 1282 LEU D CG 1 ATOM 9671 C CD1 . LEU E 2 25 ? 50.645 -94.449 40.513 1.00 52.46 ? 1282 LEU D CD1 1 ATOM 9672 C CD2 . LEU E 2 25 ? 49.404 -94.838 42.652 1.00 43.81 ? 1282 LEU D CD2 1 ATOM 9673 N N . VAL E 2 26 ? 51.841 -99.630 41.657 1.00 31.14 ? 1283 VAL D N 1 ATOM 9674 C CA . VAL E 2 26 ? 52.573 -100.439 42.630 1.00 27.99 ? 1283 VAL D CA 1 ATOM 9675 C C . VAL E 2 26 ? 53.862 -101.019 42.046 1.00 32.77 ? 1283 VAL D C 1 ATOM 9676 O O . VAL E 2 26 ? 54.897 -101.019 42.712 1.00 29.03 ? 1283 VAL D O 1 ATOM 9677 C CB . VAL E 2 26 ? 51.694 -101.592 43.171 1.00 32.21 ? 1283 VAL D CB 1 ATOM 9678 C CG1 . VAL E 2 26 ? 52.516 -102.566 44.012 1.00 33.56 ? 1283 VAL D CG1 1 ATOM 9679 C CG2 . VAL E 2 26 ? 50.540 -101.035 43.993 1.00 33.79 ? 1283 VAL D CG2 1 ATOM 9680 N N . VAL E 2 27 ? 53.798 -101.515 40.812 1.00 24.24 ? 1284 VAL D N 1 ATOM 9681 C CA . VAL E 2 27 ? 54.944 -102.186 40.198 1.00 24.30 ? 1284 VAL D CA 1 ATOM 9682 C C . VAL E 2 27 ? 55.518 -101.411 39.015 1.00 20.26 ? 1284 VAL D C 1 ATOM 9683 O O . VAL E 2 27 ? 56.505 -101.832 38.413 1.00 30.66 ? 1284 VAL D O 1 ATOM 9684 C CB . VAL E 2 27 ? 54.573 -103.606 39.724 1.00 27.59 ? 1284 VAL D CB 1 ATOM 9685 C CG1 . VAL E 2 27 ? 54.042 -104.427 40.888 1.00 35.63 ? 1284 VAL D CG1 1 ATOM 9686 C CG2 . VAL E 2 27 ? 53.553 -103.556 38.591 1.00 22.94 ? 1284 VAL D CG2 1 ATOM 9687 N N . GLY E 2 28 ? 54.898 -100.284 38.683 1.00 21.35 ? 1285 GLY D N 1 ATOM 9688 C CA . GLY E 2 28 ? 55.357 -99.458 37.582 1.00 25.98 ? 1285 GLY D CA 1 ATOM 9689 C C . GLY E 2 28 ? 54.792 -99.913 36.249 1.00 32.93 ? 1285 GLY D C 1 ATOM 9690 O O . GLY E 2 28 ? 53.717 -100.518 36.201 1.00 30.12 ? 1285 GLY D O 1 ATOM 9691 N N . PRO E 2 29 ? 55.503 -99.610 35.152 1.00 29.11 ? 1286 PRO D N 1 ATOM 9692 C CA . PRO E 2 29 ? 55.047 -100.040 33.828 1.00 23.20 ? 1286 PRO D CA 1 ATOM 9693 C C . PRO E 2 29 ? 55.318 -101.513 33.566 1.00 25.37 ? 1286 PRO D C 1 ATOM 9694 O O . PRO E 2 29 ? 56.353 -102.032 33.991 1.00 20.43 ? 1286 PRO D O 1 ATOM 9695 C CB . PRO E 2 29 ? 55.857 -99.161 32.874 1.00 25.80 ? 1286 PRO D CB 1 ATOM 9696 C CG . PRO E 2 29 ? 57.088 -98.835 33.622 1.00 35.57 ? 1286 PRO D CG 1 ATOM 9697 C CD . PRO E 2 29 ? 56.694 -98.747 35.067 1.00 31.49 ? 1286 PRO D CD 1 ATOM 9698 N N . VAL E 2 30 ? 54.395 -102.175 32.874 1.00 22.04 ? 1287 VAL D N 1 ATOM 9699 C CA . VAL E 2 30 ? 54.562 -103.579 32.525 1.00 22.35 ? 1287 VAL D CA 1 ATOM 9700 C C . VAL E 2 30 ? 54.201 -103.828 31.064 1.00 21.94 ? 1287 VAL D C 1 ATOM 9701 O O . VAL E 2 30 ? 53.250 -103.247 30.530 1.00 23.46 ? 1287 VAL D O 1 ATOM 9702 C CB . VAL E 2 30 ? 53.708 -104.497 33.431 1.00 23.67 ? 1287 VAL D CB 1 ATOM 9703 C CG1 . VAL E 2 30 ? 54.176 -104.396 34.877 1.00 24.27 ? 1287 VAL D CG1 1 ATOM 9704 C CG2 . VAL E 2 30 ? 52.226 -104.155 33.326 1.00 22.12 ? 1287 VAL D CG2 1 ATOM 9705 N N . CYS E 2 31 ? 54.990 -104.692 30.430 1.00 20.67 ? 1288 CYS D N 1 ATOM 9706 C CA . CYS E 2 31 ? 54.785 -105.087 29.045 1.00 18.52 ? 1288 CYS D CA 1 ATOM 9707 C C . CYS E 2 31 ? 55.017 -106.587 28.923 1.00 25.72 ? 1288 CYS D C 1 ATOM 9708 O O . CYS E 2 31 ? 55.561 -107.207 29.837 1.00 19.51 ? 1288 CYS D O 1 ATOM 9709 C CB . CYS E 2 31 ? 55.732 -104.326 28.115 1.00 28.64 ? 1288 CYS D CB 1 ATOM 9710 S SG . CYS E 2 31 ? 56.009 -102.611 28.583 1.00 32.46 ? 1288 CYS D SG 1 ATOM 9711 N N . PRO E 2 32 ? 54.603 -107.179 27.794 1.00 21.37 ? 1289 PRO D N 1 ATOM 9712 C CA . PRO E 2 32 ? 54.854 -108.610 27.609 1.00 28.90 ? 1289 PRO D CA 1 ATOM 9713 C C . PRO E 2 32 ? 56.328 -108.914 27.350 1.00 26.26 ? 1289 PRO D C 1 ATOM 9714 O O . PRO E 2 32 ? 57.011 -108.125 26.697 1.00 27.52 ? 1289 PRO D O 1 ATOM 9715 C CB . PRO E 2 32 ? 53.996 -108.958 26.392 1.00 25.50 ? 1289 PRO D CB 1 ATOM 9716 C CG . PRO E 2 32 ? 53.855 -107.681 25.649 1.00 28.04 ? 1289 PRO D CG 1 ATOM 9717 C CD . PRO E 2 32 ? 53.811 -106.611 26.689 1.00 21.27 ? 1289 PRO D CD 1 ATOM 9718 N N . ALA E 2 33 ? 56.806 -110.042 27.867 1.00 24.75 ? 1290 ALA D N 1 ATOM 9719 C CA . ALA E 2 33 ? 58.192 -110.459 27.673 1.00 26.96 ? 1290 ALA D CA 1 ATOM 9720 C C . ALA E 2 33 ? 58.387 -111.090 26.297 1.00 33.33 ? 1290 ALA D C 1 ATOM 9721 O O . ALA E 2 33 ? 59.515 -111.286 25.847 1.00 36.24 ? 1290 ALA D O 1 ATOM 9722 C CB . ALA E 2 33 ? 58.603 -111.431 28.760 1.00 24.37 ? 1290 ALA D CB 1 ATOM 9723 N N . ALA E 2 34 ? 57.278 -111.415 25.643 1.00 28.95 ? 1291 ALA D N 1 ATOM 9724 C CA . ALA E 2 34 ? 57.301 -111.938 24.282 1.00 33.02 ? 1291 ALA D CA 1 ATOM 9725 C C . ALA E 2 34 ? 56.017 -111.536 23.572 1.00 28.00 ? 1291 ALA D C 1 ATOM 9726 O O . ALA E 2 34 ? 55.019 -111.233 24.218 1.00 30.97 ? 1291 ALA D O 1 ATOM 9727 C CB . ALA E 2 34 ? 57.462 -113.441 24.288 1.00 32.85 ? 1291 ALA D CB 1 ATOM 9728 N N . VAL E 2 35 ? 56.045 -111.542 22.244 1.00 31.43 ? 1292 VAL D N 1 ATOM 9729 C CA . VAL E 2 35 ? 54.914 -111.071 21.450 1.00 32.96 ? 1292 VAL D CA 1 ATOM 9730 C C . VAL E 2 35 ? 53.628 -111.832 21.780 1.00 28.70 ? 1292 VAL D C 1 ATOM 9731 O O . VAL E 2 35 ? 53.569 -113.058 21.668 1.00 24.57 ? 1292 VAL D O 1 ATOM 9732 C CB . VAL E 2 35 ? 55.201 -111.200 19.941 1.00 43.97 ? 1292 VAL D CB 1 ATOM 9733 C CG1 . VAL E 2 35 ? 54.027 -110.673 19.117 1.00 36.64 ? 1292 VAL D CG1 1 ATOM 9734 C CG2 . VAL E 2 35 ? 56.480 -110.452 19.577 1.00 40.32 ? 1292 VAL D CG2 1 ATOM 9735 N N . VAL E 2 36 ? 52.604 -111.091 22.193 1.00 30.83 ? 1293 VAL D N 1 ATOM 9736 C CA . VAL E 2 36 ? 51.289 -111.663 22.458 1.00 31.76 ? 1293 VAL D CA 1 ATOM 9737 C C . VAL E 2 36 ? 50.603 -111.995 21.142 1.00 30.95 ? 1293 VAL D C 1 ATOM 9738 O O . VAL E 2 36 ? 50.791 -111.292 20.150 1.00 29.20 ? 1293 VAL D O 1 ATOM 9739 C CB . VAL E 2 36 ? 50.398 -110.693 23.263 1.00 38.07 ? 1293 VAL D CB 1 ATOM 9740 C CG1 . VAL E 2 36 ? 49.021 -111.301 23.524 1.00 29.86 ? 1293 VAL D CG1 1 ATOM 9741 C CG2 . VAL E 2 36 ? 51.067 -110.318 24.574 1.00 47.96 ? 1293 VAL D CG2 1 ATOM 9742 N N . ALA E 2 37 ? 49.812 -113.064 21.129 1.00 30.54 ? 1294 ALA D N 1 ATOM 9743 C CA . ALA E 2 37 ? 49.011 -113.390 19.956 1.00 30.94 ? 1294 ALA D CA 1 ATOM 9744 C C . ALA E 2 37 ? 48.143 -112.179 19.600 1.00 26.70 ? 1294 ALA D C 1 ATOM 9745 O O . ALA E 2 37 ? 47.330 -111.753 20.418 1.00 31.27 ? 1294 ALA D O 1 ATOM 9746 C CB . ALA E 2 37 ? 48.154 -114.615 20.217 1.00 34.33 ? 1294 ALA D CB 1 ATOM 9747 N N . PRO E 2 38 ? 48.326 -111.603 18.393 1.00 32.57 ? 1295 PRO D N 1 ATOM 9748 C CA . PRO E 2 38 ? 47.613 -110.355 18.073 1.00 43.65 ? 1295 PRO D CA 1 ATOM 9749 C C . PRO E 2 38 ? 46.089 -110.473 18.109 1.00 38.08 ? 1295 PRO D C 1 ATOM 9750 O O . PRO E 2 38 ? 45.402 -109.459 18.232 1.00 40.80 ? 1295 PRO D O 1 ATOM 9751 C CB . PRO E 2 38 ? 48.085 -110.033 16.648 1.00 44.40 ? 1295 PRO D CB 1 ATOM 9752 C CG . PRO E 2 38 ? 49.369 -110.758 16.490 1.00 47.75 ? 1295 PRO D CG 1 ATOM 9753 C CD . PRO E 2 38 ? 49.238 -112.004 17.306 1.00 43.73 ? 1295 PRO D CD 1 ATOM 9754 N N . ALA E 2 39 ? 45.571 -111.692 18.007 1.00 38.15 ? 1296 ALA D N 1 ATOM 9755 C CA . ALA E 2 39 ? 44.128 -111.902 17.990 1.00 39.97 ? 1296 ALA D CA 1 ATOM 9756 C C . ALA E 2 39 ? 43.497 -111.622 19.352 1.00 41.95 ? 1296 ALA D C 1 ATOM 9757 O O . ALA E 2 39 ? 42.337 -111.221 19.435 1.00 45.13 ? 1296 ALA D O 1 ATOM 9758 C CB . ALA E 2 39 ? 43.813 -113.315 17.549 1.00 43.84 ? 1296 ALA D CB 1 ATOM 9759 N N . VAL E 2 40 ? 44.261 -111.841 20.417 1.00 35.30 ? 1297 VAL D N 1 ATOM 9760 C CA . VAL E 2 40 ? 43.753 -111.665 21.777 1.00 39.81 ? 1297 VAL D CA 1 ATOM 9761 C C . VAL E 2 40 ? 43.367 -110.212 22.048 1.00 46.03 ? 1297 VAL D C 1 ATOM 9762 O O . VAL E 2 40 ? 44.062 -109.282 21.638 1.00 53.13 ? 1297 VAL D O 1 ATOM 9763 C CB . VAL E 2 40 ? 44.792 -112.116 22.823 1.00 44.51 ? 1297 VAL D CB 1 ATOM 9764 C CG1 . VAL E 2 40 ? 44.228 -111.982 24.232 1.00 46.55 ? 1297 VAL D CG1 1 ATOM 9765 C CG2 . VAL E 2 40 ? 45.226 -113.555 22.562 1.00 38.69 ? 1297 VAL D CG2 1 ATOM 9766 N N . SER F 2 2 ? 29.349 -180.344 29.794 1.00 67.22 ? 1259 SER F N 1 ATOM 9767 C CA . SER F 2 2 ? 28.211 -179.759 30.493 1.00 84.58 ? 1259 SER F CA 1 ATOM 9768 C C . SER F 2 2 ? 26.993 -179.698 29.573 1.00 90.44 ? 1259 SER F C 1 ATOM 9769 O O . SER F 2 2 ? 25.994 -180.378 29.808 1.00 78.94 ? 1259 SER F O 1 ATOM 9770 C CB . SER F 2 2 ? 28.564 -178.362 31.009 1.00 101.25 ? 1259 SER F CB 1 ATOM 9771 O OG . SER F 2 2 ? 27.560 -177.868 31.879 1.00 101.82 ? 1259 SER F OG 1 ATOM 9772 N N . ALA F 2 3 ? 27.083 -178.878 28.529 1.00 80.98 ? 1260 ALA F N 1 ATOM 9773 C CA . ALA F 2 3 ? 26.045 -178.817 27.505 1.00 84.16 ? 1260 ALA F CA 1 ATOM 9774 C C . ALA F 2 3 ? 26.179 -180.021 26.576 1.00 77.96 ? 1260 ALA F C 1 ATOM 9775 O O . ALA F 2 3 ? 25.188 -180.527 26.041 1.00 75.09 ? 1260 ALA F O 1 ATOM 9776 C CB . ALA F 2 3 ? 26.138 -177.512 26.720 1.00 74.57 ? 1260 ALA F CB 1 ATOM 9777 N N . SER F 2 4 ? 27.418 -180.470 26.393 1.00 82.25 ? 1261 SER F N 1 ATOM 9778 C CA . SER F 2 4 ? 27.708 -181.688 25.646 1.00 81.21 ? 1261 SER F CA 1 ATOM 9779 C C . SER F 2 4 ? 26.948 -182.864 26.250 1.00 70.96 ? 1261 SER F C 1 ATOM 9780 O O . SER F 2 4 ? 26.392 -183.693 25.529 1.00 59.81 ? 1261 SER F O 1 ATOM 9781 C CB . SER F 2 4 ? 29.214 -181.969 25.645 1.00 85.83 ? 1261 SER F CB 1 ATOM 9782 O OG . SER F 2 4 ? 29.902 -181.092 24.769 1.00 102.79 ? 1261 SER F OG 1 ATOM 9783 N N . ASP F 2 5 ? 26.923 -182.918 27.579 1.00 71.00 ? 1262 ASP F N 1 ATOM 9784 C CA . ASP F 2 5 ? 26.213 -183.966 28.305 1.00 71.91 ? 1262 ASP F CA 1 ATOM 9785 C C . ASP F 2 5 ? 24.712 -183.922 28.024 1.00 57.32 ? 1262 ASP F C 1 ATOM 9786 O O . ASP F 2 5 ? 24.091 -184.955 27.780 1.00 56.51 ? 1262 ASP F O 1 ATOM 9787 C CB . ASP F 2 5 ? 26.467 -183.838 29.811 1.00 85.20 ? 1262 ASP F CB 1 ATOM 9788 C CG . ASP F 2 5 ? 27.830 -184.366 30.220 1.00 96.02 ? 1262 ASP F CG 1 ATOM 9789 O OD1 . ASP F 2 5 ? 28.738 -184.404 29.363 1.00 84.95 ? 1262 ASP F OD1 1 ATOM 9790 O OD2 . ASP F 2 5 ? 27.994 -184.739 31.401 1.00 80.96 ? 1262 ASP F OD2 1 ATOM 9791 N N . ILE F 2 6 ? 24.136 -182.724 28.062 1.00 52.72 ? 1263 ILE F N 1 ATOM 9792 C CA . ILE F 2 6 ? 22.714 -182.549 27.781 1.00 54.00 ? 1263 ILE F CA 1 ATOM 9793 C C . ILE F 2 6 ? 22.404 -182.960 26.346 1.00 52.98 ? 1263 ILE F C 1 ATOM 9794 O O . ILE F 2 6 ? 21.459 -183.711 26.098 1.00 50.14 ? 1263 ILE F O 1 ATOM 9795 C CB . ILE F 2 6 ? 22.267 -181.088 28.014 1.00 52.75 ? 1263 ILE F CB 1 ATOM 9796 C CG1 . ILE F 2 6 ? 22.358 -180.743 29.504 1.00 56.84 ? 1263 ILE F CG1 1 ATOM 9797 C CG2 . ILE F 2 6 ? 20.834 -180.868 27.520 1.00 47.91 ? 1263 ILE F CG2 1 ATOM 9798 C CD1 . ILE F 2 6 ? 22.153 -179.271 29.825 1.00 56.86 ? 1263 ILE F CD1 1 ATOM 9799 N N . THR F 2 7 ? 23.200 -182.462 25.404 1.00 45.30 ? 1264 THR F N 1 ATOM 9800 C CA . THR F 2 7 ? 23.034 -182.808 23.997 1.00 44.47 ? 1264 THR F CA 1 ATOM 9801 C C . THR F 2 7 ? 23.111 -184.318 23.793 1.00 41.90 ? 1264 THR F C 1 ATOM 9802 O O . THR F 2 7 ? 22.244 -184.918 23.149 1.00 39.59 ? 1264 THR F O 1 ATOM 9803 C CB . THR F 2 7 ? 24.105 -182.126 23.118 1.00 46.62 ? 1264 THR F CB 1 ATOM 9804 O OG1 . THR F 2 7 ? 24.106 -180.714 23.362 1.00 60.33 ? 1264 THR F OG1 1 ATOM 9805 C CG2 . THR F 2 7 ? 23.833 -182.377 21.643 1.00 42.31 ? 1264 THR F CG2 1 ATOM 9806 N N . GLN F 2 8 ? 24.146 -184.934 24.353 1.00 40.23 ? 1265 GLN F N 1 ATOM 9807 C CA . GLN F 2 8 ? 24.338 -186.367 24.192 1.00 44.44 ? 1265 GLN F CA 1 ATOM 9808 C C . GLN F 2 8 ? 23.223 -187.138 24.891 1.00 37.43 ? 1265 GLN F C 1 ATOM 9809 O O . GLN F 2 8 ? 22.802 -188.187 24.412 1.00 37.77 ? 1265 GLN F O 1 ATOM 9810 C CB . GLN F 2 8 ? 25.704 -186.801 24.732 1.00 43.83 ? 1265 GLN F CB 1 ATOM 9811 C CG . GLN F 2 8 ? 26.082 -188.231 24.366 1.00 59.83 ? 1265 GLN F CG 1 ATOM 9812 C CD . GLN F 2 8 ? 25.984 -188.497 22.872 1.00 80.69 ? 1265 GLN F CD 1 ATOM 9813 O OE1 . GLN F 2 8 ? 26.684 -187.875 22.072 1.00 74.87 ? 1265 GLN F OE1 1 ATOM 9814 N NE2 . GLN F 2 8 ? 25.100 -189.412 22.489 1.00 60.64 ? 1265 GLN F NE2 1 ATOM 9815 N N . HIS F 2 9 ? 22.743 -186.616 26.016 1.00 35.40 ? 1266 HIS F N 1 ATOM 9816 C CA . HIS F 2 9 ? 21.615 -187.228 26.713 1.00 38.71 ? 1266 HIS F CA 1 ATOM 9817 C C . HIS F 2 9 ? 20.363 -187.159 25.848 1.00 37.17 ? 1266 HIS F C 1 ATOM 9818 O O . HIS F 2 9 ? 19.589 -188.114 25.781 1.00 31.36 ? 1266 HIS F O 1 ATOM 9819 C CB . HIS F 2 9 ? 21.355 -186.546 28.060 1.00 40.57 ? 1266 HIS F CB 1 ATOM 9820 C CG . HIS F 2 9 ? 20.132 -187.050 28.763 1.00 48.74 ? 1266 HIS F CG 1 ATOM 9821 N ND1 . HIS F 2 9 ? 20.071 -188.295 29.352 1.00 47.87 ? 1266 HIS F ND1 1 ATOM 9822 C CD2 . HIS F 2 9 ? 18.919 -186.481 28.961 1.00 43.09 ? 1266 HIS F CD2 1 ATOM 9823 C CE1 . HIS F 2 9 ? 18.876 -188.469 29.888 1.00 42.53 ? 1266 HIS F CE1 1 ATOM 9824 N NE2 . HIS F 2 9 ? 18.157 -187.383 29.665 1.00 52.30 ? 1266 HIS F NE2 1 ATOM 9825 N N . LEU F 2 10 ? 20.164 -186.022 25.190 1.00 32.51 ? 1267 LEU F N 1 ATOM 9826 C CA . LEU F 2 10 ? 19.044 -185.870 24.269 1.00 30.71 ? 1267 LEU F CA 1 ATOM 9827 C C . LEU F 2 10 ? 19.168 -186.840 23.101 1.00 26.15 ? 1267 LEU F C 1 ATOM 9828 O O . LEU F 2 10 ? 18.189 -187.481 22.718 1.00 22.83 ? 1267 LEU F O 1 ATOM 9829 C CB . LEU F 2 10 ? 18.956 -184.431 23.757 1.00 36.21 ? 1267 LEU F CB 1 ATOM 9830 C CG . LEU F 2 10 ? 18.243 -183.437 24.681 1.00 39.57 ? 1267 LEU F CG 1 ATOM 9831 C CD1 . LEU F 2 10 ? 18.455 -182.014 24.197 1.00 43.90 ? 1267 LEU F CD1 1 ATOM 9832 C CD2 . LEU F 2 10 ? 16.758 -183.746 24.763 1.00 45.83 ? 1267 LEU F CD2 1 ATOM 9833 N N . ASN F 2 11 ? 20.365 -186.952 22.532 1.00 26.73 ? 1268 ASN F N 1 ATOM 9834 C CA . ASN F 2 11 ? 20.589 -187.927 21.468 1.00 29.25 ? 1268 ASN F CA 1 ATOM 9835 C C . ASN F 2 11 ? 20.333 -189.352 21.955 1.00 29.86 ? 1268 ASN F C 1 ATOM 9836 O O . ASN F 2 11 ? 19.717 -190.154 21.255 1.00 25.42 ? 1268 ASN F O 1 ATOM 9837 C CB . ASN F 2 11 ? 22.012 -187.813 20.915 1.00 30.72 ? 1268 ASN F CB 1 ATOM 9838 C CG . ASN F 2 11 ? 22.252 -188.739 19.733 1.00 42.75 ? 1268 ASN F CG 1 ATOM 9839 O OD1 . ASN F 2 11 ? 22.689 -189.877 19.900 1.00 37.45 ? 1268 ASN F OD1 1 ATOM 9840 N ND2 . ASN F 2 11 ? 21.957 -188.255 18.530 1.00 35.13 ? 1268 ASN F ND2 1 ATOM 9841 N N . ASP F 2 12 ? 20.800 -189.658 23.161 1.00 31.70 ? 1269 ASP F N 1 ATOM 9842 C CA . ASP F 2 12 ? 20.606 -190.982 23.743 1.00 25.46 ? 1269 ASP F CA 1 ATOM 9843 C C . ASP F 2 12 ? 19.131 -191.261 24.028 1.00 22.27 ? 1269 ASP F C 1 ATOM 9844 O O . ASP F 2 12 ? 18.722 -192.417 24.115 1.00 23.52 ? 1269 ASP F O 1 ATOM 9845 C CB . ASP F 2 12 ? 21.418 -191.127 25.036 1.00 33.49 ? 1269 ASP F CB 1 ATOM 9846 C CG . ASP F 2 12 ? 22.917 -191.119 24.795 1.00 44.46 ? 1269 ASP F CG 1 ATOM 9847 O OD1 . ASP F 2 12 ? 23.346 -191.425 23.662 1.00 50.05 ? 1269 ASP F OD1 1 ATOM 9848 O OD2 . ASP F 2 12 ? 23.669 -190.812 25.745 1.00 49.67 ? 1269 ASP F OD2 1 ATOM 9849 N N . SER F 2 13 ? 18.336 -190.203 24.160 1.00 23.02 ? 1270 SER F N 1 ATOM 9850 C CA . SER F 2 13 ? 16.918 -190.343 24.490 1.00 23.90 ? 1270 SER F CA 1 ATOM 9851 C C . SER F 2 13 ? 16.024 -190.381 23.252 1.00 21.87 ? 1270 SER F C 1 ATOM 9852 O O . SER F 2 13 ? 14.805 -190.519 23.368 1.00 18.03 ? 1270 SER F O 1 ATOM 9853 C CB . SER F 2 13 ? 16.473 -189.202 25.403 1.00 26.65 ? 1270 SER F CB 1 ATOM 9854 O OG . SER F 2 13 ? 17.135 -189.266 26.653 1.00 36.17 ? 1270 SER F OG 1 ATOM 9855 N N . GLY F 2 14 ? 16.629 -190.241 22.076 1.00 22.62 ? 1271 GLY F N 1 ATOM 9856 C CA . GLY F 2 14 ? 15.912 -190.395 20.824 1.00 21.31 ? 1271 GLY F CA 1 ATOM 9857 C C . GLY F 2 14 ? 15.633 -189.111 20.060 1.00 23.17 ? 1271 GLY F C 1 ATOM 9858 O O . GLY F 2 14 ? 14.852 -189.124 19.108 1.00 20.28 ? 1271 GLY F O 1 ATOM 9859 N N . LEU F 2 15 ? 16.257 -188.005 20.460 1.00 22.28 ? 1272 LEU F N 1 ATOM 9860 C CA . LEU F 2 15 ? 16.106 -186.752 19.722 1.00 27.49 ? 1272 LEU F CA 1 ATOM 9861 C C . LEU F 2 15 ? 16.581 -186.942 18.286 1.00 23.85 ? 1272 LEU F C 1 ATOM 9862 O O . LEU F 2 15 ? 17.715 -187.358 18.047 1.00 24.67 ? 1272 LEU F O 1 ATOM 9863 C CB . LEU F 2 15 ? 16.886 -185.615 20.386 1.00 30.49 ? 1272 LEU F CB 1 ATOM 9864 C CG . LEU F 2 15 ? 16.726 -184.239 19.724 1.00 34.88 ? 1272 LEU F CG 1 ATOM 9865 C CD1 . LEU F 2 15 ? 15.362 -183.642 20.039 1.00 26.11 ? 1272 LEU F CD1 1 ATOM 9866 C CD2 . LEU F 2 15 ? 17.839 -183.289 20.142 1.00 37.56 ? 1272 LEU F CD2 1 ATOM 9867 N N . GLY F 2 16 ? 15.705 -186.630 17.336 1.00 25.24 ? 1273 GLY F N 1 ATOM 9868 C CA . GLY F 2 16 ? 15.973 -186.894 15.936 1.00 27.85 ? 1273 GLY F CA 1 ATOM 9869 C C . GLY F 2 16 ? 16.729 -185.782 15.238 1.00 28.43 ? 1273 GLY F C 1 ATOM 9870 O O . GLY F 2 16 ? 17.017 -184.745 15.833 1.00 25.63 ? 1273 GLY F O 1 ATOM 9871 N N . PRO F 2 17 ? 17.058 -185.998 13.957 1.00 29.29 ? 1274 PRO F N 1 ATOM 9872 C CA . PRO F 2 17 ? 17.772 -185.005 13.151 1.00 34.05 ? 1274 PRO F CA 1 ATOM 9873 C C . PRO F 2 17 ? 16.893 -183.817 12.785 1.00 30.89 ? 1274 PRO F C 1 ATOM 9874 O O . PRO F 2 17 ? 15.692 -183.986 12.571 1.00 28.08 ? 1274 PRO F O 1 ATOM 9875 C CB . PRO F 2 17 ? 18.167 -185.793 11.901 1.00 32.22 ? 1274 PRO F CB 1 ATOM 9876 C CG . PRO F 2 17 ? 17.125 -186.840 11.781 1.00 31.56 ? 1274 PRO F CG 1 ATOM 9877 C CD . PRO F 2 17 ? 16.760 -187.219 13.189 1.00 30.06 ? 1274 PRO F CD 1 ATOM 9878 N N . ALA F 2 18 ? 17.484 -182.629 12.726 1.00 38.21 ? 1275 ALA F N 1 ATOM 9879 C CA . ALA F 2 18 ? 16.788 -181.463 12.203 1.00 46.04 ? 1275 ALA F CA 1 ATOM 9880 C C . ALA F 2 18 ? 16.682 -181.594 10.690 1.00 38.80 ? 1275 ALA F C 1 ATOM 9881 O O . ALA F 2 18 ? 17.649 -181.341 9.970 1.00 53.08 ? 1275 ALA F O 1 ATOM 9882 C CB . ALA F 2 18 ? 17.512 -180.185 12.583 1.00 47.89 ? 1275 ALA F CB 1 ATOM 9883 N N . VAL F 2 19 ? 15.509 -182.002 10.217 1.00 35.54 ? 1276 VAL F N 1 ATOM 9884 C CA . VAL F 2 19 ? 15.284 -182.208 8.791 1.00 42.46 ? 1276 VAL F CA 1 ATOM 9885 C C . VAL F 2 19 ? 14.319 -181.166 8.253 1.00 41.18 ? 1276 VAL F C 1 ATOM 9886 O O . VAL F 2 19 ? 13.462 -180.664 8.980 1.00 36.66 ? 1276 VAL F O 1 ATOM 9887 C CB . VAL F 2 19 ? 14.732 -183.615 8.497 1.00 38.75 ? 1276 VAL F CB 1 ATOM 9888 C CG1 . VAL F 2 19 ? 15.732 -184.671 8.938 1.00 38.24 ? 1276 VAL F CG1 1 ATOM 9889 C CG2 . VAL F 2 19 ? 13.387 -183.825 9.180 1.00 40.41 ? 1276 VAL F CG2 1 ATOM 9890 N N . GLU F 2 20 ? 14.466 -180.852 6.972 1.00 34.77 ? 1277 GLU F N 1 ATOM 9891 C CA . GLU F 2 20 ? 13.655 -179.826 6.335 1.00 39.13 ? 1277 GLU F CA 1 ATOM 9892 C C . GLU F 2 20 ? 12.521 -180.436 5.515 1.00 35.64 ? 1277 GLU F C 1 ATOM 9893 O O . GLU F 2 20 ? 11.538 -179.760 5.214 1.00 40.00 ? 1277 GLU F O 1 ATOM 9894 C CB . GLU F 2 20 ? 14.535 -178.941 5.441 1.00 46.50 ? 1277 GLU F CB 1 ATOM 9895 C CG . GLU F 2 20 ? 13.835 -177.709 4.873 1.00 84.42 ? 1277 GLU F CG 1 ATOM 9896 C CD . GLU F 2 20 ? 13.159 -176.867 5.942 1.00 90.94 ? 1277 GLU F CD 1 ATOM 9897 O OE1 . GLU F 2 20 ? 13.801 -176.588 6.977 1.00 82.97 ? 1277 GLU F OE1 1 ATOM 9898 O OE2 . GLU F 2 20 ? 11.983 -176.489 5.748 1.00 84.02 ? 1277 GLU F OE2 1 ATOM 9899 N N A CYS F 2 21 ? 12.661 -181.718 5.183 0.59 32.07 ? 1278 CYS F N 1 ATOM 9900 N N B CYS F 2 21 ? 12.654 -181.708 5.153 0.41 32.10 ? 1278 CYS F N 1 ATOM 9901 C CA A CYS F 2 21 ? 11.744 -182.389 4.267 0.59 30.16 ? 1278 CYS F CA 1 ATOM 9902 C CA B CYS F 2 21 ? 11.657 -182.356 4.310 0.41 30.17 ? 1278 CYS F CA 1 ATOM 9903 C C A CYS F 2 21 ? 11.574 -183.872 4.591 0.59 29.02 ? 1278 CYS F C 1 ATOM 9904 C C B CYS F 2 21 ? 11.567 -183.856 4.557 0.41 29.06 ? 1278 CYS F C 1 ATOM 9905 O O A CYS F 2 21 ? 12.536 -184.545 4.964 0.59 27.62 ? 1278 CYS F O 1 ATOM 9906 O O B CYS F 2 21 ? 12.565 -184.518 4.846 0.41 27.73 ? 1278 CYS F O 1 ATOM 9907 C CB A CYS F 2 21 ? 12.247 -182.242 2.830 0.59 33.51 ? 1278 CYS F CB 1 ATOM 9908 C CB B CYS F 2 21 ? 11.964 -182.096 2.834 0.41 33.19 ? 1278 CYS F CB 1 ATOM 9909 S SG A CYS F 2 21 ? 11.176 -182.991 1.581 0.59 35.52 ? 1278 CYS F SG 1 ATOM 9910 S SG B CYS F 2 21 ? 11.462 -180.459 2.243 0.41 40.86 ? 1278 CYS F SG 1 ATOM 9911 N N . LEU F 2 22 ? 10.349 -184.373 4.440 1.00 27.39 ? 1279 LEU F N 1 ATOM 9912 C CA . LEU F 2 22 ? 10.082 -185.806 4.526 1.00 30.80 ? 1279 LEU F CA 1 ATOM 9913 C C . LEU F 2 22 ? 9.552 -186.277 3.177 1.00 30.12 ? 1279 LEU F C 1 ATOM 9914 O O . LEU F 2 22 ? 8.876 -185.523 2.482 1.00 28.40 ? 1279 LEU F O 1 ATOM 9915 C CB . LEU F 2 22 ? 9.075 -186.123 5.635 1.00 26.06 ? 1279 LEU F CB 1 ATOM 9916 C CG . LEU F 2 22 ? 9.615 -186.602 6.984 1.00 36.45 ? 1279 LEU F CG 1 ATOM 9917 C CD1 . LEU F 2 22 ? 10.668 -185.662 7.533 1.00 29.87 ? 1279 LEU F CD1 1 ATOM 9918 C CD2 . LEU F 2 22 ? 8.469 -186.742 7.972 1.00 38.28 ? 1279 LEU F CD2 1 ATOM 9919 N N . GLU F 2 23 ? 9.871 -187.514 2.807 1.00 23.58 ? 1280 GLU F N 1 ATOM 9920 C CA . GLU F 2 23 ? 9.340 -188.119 1.588 1.00 26.72 ? 1280 GLU F CA 1 ATOM 9921 C C . GLU F 2 23 ? 8.313 -189.184 1.945 1.00 24.05 ? 1280 GLU F C 1 ATOM 9922 O O . GLU F 2 23 ? 8.579 -190.065 2.760 1.00 28.65 ? 1280 GLU F O 1 ATOM 9923 C CB . GLU F 2 23 ? 10.463 -188.729 0.742 1.00 34.13 ? 1280 GLU F CB 1 ATOM 9924 C CG . GLU F 2 23 ? 9.981 -189.528 -0.470 1.00 42.15 ? 1280 GLU F CG 1 ATOM 9925 C CD . GLU F 2 23 ? 9.178 -188.691 -1.449 1.00 54.43 ? 1280 GLU F CD 1 ATOM 9926 O OE1 . GLU F 2 23 ? 8.333 -189.263 -2.171 1.00 61.95 ? 1280 GLU F OE1 1 ATOM 9927 O OE2 . GLU F 2 23 ? 9.397 -187.463 -1.503 1.00 65.44 ? 1280 GLU F OE2 1 ATOM 9928 N N . ASN F 2 24 ? 7.140 -189.088 1.329 1.00 21.42 ? 1281 ASN F N 1 ATOM 9929 C CA . ASN F 2 24 ? 6.070 -190.057 1.526 1.00 23.33 ? 1281 ASN F CA 1 ATOM 9930 C C . ASN F 2 24 ? 5.574 -190.576 0.181 1.00 30.14 ? 1281 ASN F C 1 ATOM 9931 O O . ASN F 2 24 ? 5.344 -189.798 -0.748 1.00 25.37 ? 1281 ASN F O 1 ATOM 9932 C CB . ASN F 2 24 ? 4.924 -189.428 2.318 1.00 26.38 ? 1281 ASN F CB 1 ATOM 9933 C CG . ASN F 2 24 ? 3.752 -190.368 2.496 1.00 26.65 ? 1281 ASN F CG 1 ATOM 9934 O OD1 . ASN F 2 24 ? 2.877 -190.450 1.638 1.00 25.47 ? 1281 ASN F OD1 1 ATOM 9935 N ND2 . ASN F 2 24 ? 3.723 -191.076 3.619 1.00 29.77 ? 1281 ASN F ND2 1 ATOM 9936 N N . LEU F 2 25 ? 5.459 -191.888 0.068 1.00 28.95 ? 1282 LEU F N 1 ATOM 9937 C CA . LEU F 2 25 ? 5.066 -192.542 -1.173 1.00 36.60 ? 1282 LEU F CA 1 ATOM 9938 C C . LEU F 2 25 ? 3.639 -192.295 -1.622 1.00 30.57 ? 1282 LEU F C 1 ATOM 9939 O O . LEU F 2 25 ? 3.308 -192.520 -2.760 1.00 37.04 ? 1282 LEU F O 1 ATOM 9940 C CB . LEU F 2 25 ? 5.377 -194.041 -1.132 1.00 37.02 ? 1282 LEU F CB 1 ATOM 9941 C CG . LEU F 2 25 ? 6.802 -194.427 -0.737 1.00 50.82 ? 1282 LEU F CG 1 ATOM 9942 C CD1 . LEU F 2 25 ? 7.038 -195.925 -0.841 1.00 40.20 ? 1282 LEU F CD1 1 ATOM 9943 C CD2 . LEU F 2 25 ? 7.834 -193.671 -1.545 1.00 44.72 ? 1282 LEU F CD2 1 ATOM 9944 N N . VAL F 2 26 ? 2.793 -191.857 -0.715 1.00 31.54 ? 1283 VAL F N 1 ATOM 9945 C CA . VAL F 2 26 ? 1.386 -191.630 -1.035 1.00 25.78 ? 1283 VAL F CA 1 ATOM 9946 C C . VAL F 2 26 ? 1.129 -190.187 -1.473 1.00 38.17 ? 1283 VAL F C 1 ATOM 9947 O O . VAL F 2 26 ? 0.363 -189.950 -2.408 1.00 43.78 ? 1283 VAL F O 1 ATOM 9948 C CB . VAL F 2 26 ? 0.478 -191.963 0.164 1.00 31.19 ? 1283 VAL F CB 1 ATOM 9949 C CG1 . VAL F 2 26 ? -0.962 -191.559 -0.115 1.00 30.85 ? 1283 VAL F CG1 1 ATOM 9950 C CG2 . VAL F 2 26 ? 0.548 -193.447 0.476 1.00 37.22 ? 1283 VAL F CG2 1 ATOM 9951 N N . VAL F 2 27 ? 1.774 -189.235 -0.802 1.00 31.20 ? 1284 VAL F N 1 ATOM 9952 C CA . VAL F 2 27 ? 1.499 -187.815 -1.019 1.00 30.20 ? 1284 VAL F CA 1 ATOM 9953 C C . VAL F 2 27 ? 2.710 -187.052 -1.551 1.00 26.16 ? 1284 VAL F C 1 ATOM 9954 O O . VAL F 2 27 ? 2.607 -185.870 -1.879 1.00 31.77 ? 1284 VAL F O 1 ATOM 9955 C CB . VAL F 2 27 ? 1.015 -187.138 0.287 1.00 30.57 ? 1284 VAL F CB 1 ATOM 9956 C CG1 . VAL F 2 27 ? -0.150 -187.914 0.877 1.00 36.12 ? 1284 VAL F CG1 1 ATOM 9957 C CG2 . VAL F 2 27 ? 2.144 -187.026 1.313 1.00 25.45 ? 1284 VAL F CG2 1 ATOM 9958 N N . GLY F 2 28 ? 3.853 -187.723 -1.636 1.00 25.77 ? 1285 GLY F N 1 ATOM 9959 C CA . GLY F 2 28 ? 5.064 -187.091 -2.125 1.00 17.78 ? 1285 GLY F CA 1 ATOM 9960 C C . GLY F 2 28 ? 5.794 -186.343 -1.024 1.00 23.86 ? 1285 GLY F C 1 ATOM 9961 O O . GLY F 2 28 ? 5.548 -186.585 0.157 1.00 26.36 ? 1285 GLY F O 1 ATOM 9962 N N . PRO F 2 29 ? 6.698 -185.424 -1.404 1.00 22.06 ? 1286 PRO F N 1 ATOM 9963 C CA . PRO F 2 29 ? 7.489 -184.687 -0.412 1.00 22.54 ? 1286 PRO F CA 1 ATOM 9964 C C . PRO F 2 29 ? 6.633 -183.755 0.441 1.00 26.82 ? 1286 PRO F C 1 ATOM 9965 O O . PRO F 2 29 ? 5.704 -183.135 -0.079 1.00 23.24 ? 1286 PRO F O 1 ATOM 9966 C CB . PRO F 2 29 ? 8.479 -183.877 -1.264 1.00 27.07 ? 1286 PRO F CB 1 ATOM 9967 C CG . PRO F 2 29 ? 8.341 -184.381 -2.665 1.00 26.19 ? 1286 PRO F CG 1 ATOM 9968 C CD . PRO F 2 29 ? 6.984 -184.982 -2.778 1.00 24.23 ? 1286 PRO F CD 1 ATOM 9969 N N . VAL F 2 30 ? 6.941 -183.665 1.732 1.00 22.27 ? 1287 VAL F N 1 ATOM 9970 C CA . VAL F 2 30 ? 6.267 -182.725 2.619 1.00 23.64 ? 1287 VAL F CA 1 ATOM 9971 C C . VAL F 2 30 ? 7.283 -181.931 3.430 1.00 23.51 ? 1287 VAL F C 1 ATOM 9972 O O . VAL F 2 30 ? 8.326 -182.454 3.839 1.00 23.32 ? 1287 VAL F O 1 ATOM 9973 C CB . VAL F 2 30 ? 5.286 -183.437 3.573 1.00 25.21 ? 1287 VAL F CB 1 ATOM 9974 C CG1 . VAL F 2 30 ? 4.099 -183.986 2.790 1.00 22.79 ? 1287 VAL F CG1 1 ATOM 9975 C CG2 . VAL F 2 30 ? 5.989 -184.541 4.357 1.00 22.86 ? 1287 VAL F CG2 1 ATOM 9976 N N . CYS F 2 31 ? 6.956 -180.660 3.648 1.00 19.95 ? 1288 CYS F N 1 ATOM 9977 C CA . CYS F 2 31 ? 7.834 -179.718 4.332 1.00 17.59 ? 1288 CYS F CA 1 ATOM 9978 C C . CYS F 2 31 ? 7.027 -178.846 5.282 1.00 22.67 ? 1288 CYS F C 1 ATOM 9979 O O . CYS F 2 31 ? 5.815 -178.707 5.120 1.00 22.43 ? 1288 CYS F O 1 ATOM 9980 C CB . CYS F 2 31 ? 8.567 -178.833 3.319 1.00 31.90 ? 1288 CYS F CB 1 ATOM 9981 S SG . CYS F 2 31 ? 9.570 -179.723 2.123 1.00 47.29 ? 1288 CYS F SG 1 ATOM 9982 N N . PRO F 2 32 ? 7.695 -178.241 6.271 1.00 21.55 ? 1289 PRO F N 1 ATOM 9983 C CA . PRO F 2 32 ? 6.963 -177.337 7.159 1.00 32.18 ? 1289 PRO F CA 1 ATOM 9984 C C . PRO F 2 32 ? 6.669 -176.000 6.481 1.00 29.65 ? 1289 PRO F C 1 ATOM 9985 O O . PRO F 2 32 ? 7.559 -175.428 5.853 1.00 30.60 ? 1289 PRO F O 1 ATOM 9986 C CB . PRO F 2 32 ? 7.917 -177.165 8.339 1.00 26.63 ? 1289 PRO F CB 1 ATOM 9987 C CG . PRO F 2 32 ? 9.268 -177.336 7.749 1.00 29.93 ? 1289 PRO F CG 1 ATOM 9988 C CD . PRO F 2 32 ? 9.121 -178.335 6.632 1.00 29.13 ? 1289 PRO F CD 1 ATOM 9989 N N . ALA F 2 33 ? 5.434 -175.522 6.595 1.00 24.35 ? 1290 ALA F N 1 ATOM 9990 C CA . ALA F 2 33 ? 5.057 -174.238 6.012 1.00 29.11 ? 1290 ALA F CA 1 ATOM 9991 C C . ALA F 2 33 ? 5.801 -173.096 6.705 1.00 35.33 ? 1290 ALA F C 1 ATOM 9992 O O . ALA F 2 33 ? 6.196 -172.123 6.062 1.00 34.12 ? 1290 ALA F O 1 ATOM 9993 C CB . ALA F 2 33 ? 3.554 -174.033 6.110 1.00 28.12 ? 1290 ALA F CB 1 ATOM 9994 N N . ALA F 2 34 ? 5.983 -173.228 8.017 1.00 30.92 ? 1291 ALA F N 1 ATOM 9995 C CA . ALA F 2 34 ? 6.725 -172.252 8.812 1.00 36.22 ? 1291 ALA F CA 1 ATOM 9996 C C . ALA F 2 34 ? 7.852 -172.944 9.572 1.00 37.36 ? 1291 ALA F C 1 ATOM 9997 O O . ALA F 2 34 ? 7.808 -174.151 9.792 1.00 34.16 ? 1291 ALA F O 1 ATOM 9998 C CB . ALA F 2 34 ? 5.797 -171.534 9.775 1.00 31.54 ? 1291 ALA F CB 1 ATOM 9999 N N . VAL F 2 35 ? 8.856 -172.175 9.976 1.00 30.94 ? 1292 VAL F N 1 ATOM 10000 C CA . VAL F 2 35 ? 10.022 -172.737 10.649 1.00 32.36 ? 1292 VAL F CA 1 ATOM 10001 C C . VAL F 2 35 ? 9.628 -173.408 11.965 1.00 34.75 ? 1292 VAL F C 1 ATOM 10002 O O . VAL F 2 35 ? 8.980 -172.798 12.818 1.00 25.31 ? 1292 VAL F O 1 ATOM 10003 C CB . VAL F 2 35 ? 11.085 -171.654 10.925 1.00 43.86 ? 1292 VAL F CB 1 ATOM 10004 C CG1 . VAL F 2 35 ? 12.306 -172.253 11.619 1.00 44.26 ? 1292 VAL F CG1 1 ATOM 10005 C CG2 . VAL F 2 35 ? 11.498 -170.978 9.624 1.00 47.22 ? 1292 VAL F CG2 1 ATOM 10006 N N . VAL F 2 36 ? 10.017 -174.672 12.110 1.00 31.88 ? 1293 VAL F N 1 ATOM 10007 C CA . VAL F 2 36 ? 9.785 -175.426 13.339 1.00 32.70 ? 1293 VAL F CA 1 ATOM 10008 C C . VAL F 2 36 ? 10.749 -174.961 14.423 1.00 30.43 ? 1293 VAL F C 1 ATOM 10009 O O . VAL F 2 36 ? 11.889 -174.600 14.131 1.00 30.90 ? 1293 VAL F O 1 ATOM 10010 C CB . VAL F 2 36 ? 9.964 -176.947 13.111 1.00 32.96 ? 1293 VAL F CB 1 ATOM 10011 C CG1 . VAL F 2 36 ? 9.742 -177.726 14.403 1.00 30.81 ? 1293 VAL F CG1 1 ATOM 10012 C CG2 . VAL F 2 36 ? 9.016 -177.439 12.030 1.00 35.36 ? 1293 VAL F CG2 1 ATOM 10013 N N . ALA F 2 37 ? 10.293 -174.969 15.671 1.00 25.39 ? 1294 ALA F N 1 ATOM 10014 C CA . ALA F 2 37 ? 11.157 -174.617 16.792 1.00 31.09 ? 1294 ALA F CA 1 ATOM 10015 C C . ALA F 2 37 ? 12.403 -175.507 16.774 1.00 29.40 ? 1294 ALA F C 1 ATOM 10016 O O . ALA F 2 37 ? 12.283 -176.725 16.889 1.00 34.51 ? 1294 ALA F O 1 ATOM 10017 C CB . ALA F 2 37 ? 10.409 -174.763 18.101 1.00 27.88 ? 1294 ALA F CB 1 ATOM 10018 N N . PRO F 2 38 ? 13.602 -174.908 16.618 1.00 36.96 ? 1295 PRO F N 1 ATOM 10019 C CA . PRO F 2 38 ? 14.814 -175.718 16.419 1.00 44.85 ? 1295 PRO F CA 1 ATOM 10020 C C . PRO F 2 38 ? 15.063 -176.749 17.519 1.00 44.37 ? 1295 PRO F C 1 ATOM 10021 O O . PRO F 2 38 ? 15.679 -177.783 17.260 1.00 44.59 ? 1295 PRO F O 1 ATOM 10022 C CB . PRO F 2 38 ? 15.938 -174.673 16.406 1.00 43.09 ? 1295 PRO F CB 1 ATOM 10023 C CG . PRO F 2 38 ? 15.281 -173.407 16.033 1.00 55.22 ? 1295 PRO F CG 1 ATOM 10024 C CD . PRO F 2 38 ? 13.913 -173.467 16.630 1.00 42.28 ? 1295 PRO F CD 1 ATOM 10025 N N . ALA F 2 39 ? 14.588 -176.467 18.727 1.00 33.69 ? 1296 ALA F N 1 ATOM 10026 C CA . ALA F 2 39 ? 14.776 -177.373 19.853 1.00 40.20 ? 1296 ALA F CA 1 ATOM 10027 C C . ALA F 2 39 ? 14.075 -178.711 19.629 1.00 47.91 ? 1296 ALA F C 1 ATOM 10028 O O . ALA F 2 39 ? 14.480 -179.732 20.184 1.00 45.42 ? 1296 ALA F O 1 ATOM 10029 C CB . ALA F 2 39 ? 14.273 -176.733 21.120 1.00 39.38 ? 1296 ALA F CB 1 ATOM 10030 N N . VAL F 2 40 ? 13.019 -178.699 18.821 1.00 38.86 ? 1297 VAL F N 1 ATOM 10031 C CA . VAL F 2 40 ? 12.274 -179.918 18.523 1.00 45.89 ? 1297 VAL F CA 1 ATOM 10032 C C . VAL F 2 40 ? 13.078 -180.809 17.583 1.00 44.96 ? 1297 VAL F C 1 ATOM 10033 O O . VAL F 2 40 ? 13.072 -182.032 17.717 1.00 60.74 ? 1297 VAL F O 1 ATOM 10034 C CB . VAL F 2 40 ? 10.901 -179.611 17.886 1.00 49.22 ? 1297 VAL F CB 1 ATOM 10035 C CG1 . VAL F 2 40 ? 10.088 -180.891 17.727 1.00 50.97 ? 1297 VAL F CG1 1 ATOM 10036 C CG2 . VAL F 2 40 ? 10.132 -178.604 18.728 1.00 50.65 ? 1297 VAL F CG2 1 HETATM 10037 C C1 . NAG G 3 . ? 32.307 -156.833 26.341 1.00 27.73 ? 501 NAG A C1 1 HETATM 10038 C C2 . NAG G 3 . ? 32.527 -156.865 24.824 1.00 34.16 ? 501 NAG A C2 1 HETATM 10039 C C3 . NAG G 3 . ? 33.444 -158.028 24.444 1.00 30.56 ? 501 NAG A C3 1 HETATM 10040 C C4 . NAG G 3 . ? 34.737 -157.971 25.249 1.00 31.12 ? 501 NAG A C4 1 HETATM 10041 C C5 . NAG G 3 . ? 34.418 -157.924 26.738 1.00 35.58 ? 501 NAG A C5 1 HETATM 10042 C C6 . NAG G 3 . ? 35.647 -157.771 27.603 1.00 31.31 ? 501 NAG A C6 1 HETATM 10043 C C7 . NAG G 3 . ? 30.621 -155.983 23.495 1.00 35.38 ? 501 NAG A C7 1 HETATM 10044 C C8 . NAG G 3 . ? 31.297 -154.646 23.516 1.00 24.61 ? 501 NAG A C8 1 HETATM 10045 N N2 . NAG G 3 . ? 31.249 -156.987 24.126 1.00 23.26 ? 501 NAG A N2 1 HETATM 10046 O O3 . NAG G 3 . ? 33.735 -157.969 23.054 1.00 42.77 ? 501 NAG A O3 1 HETATM 10047 O O4 . NAG G 3 . ? 35.538 -159.116 24.975 1.00 43.89 ? 501 NAG A O4 1 HETATM 10048 O O5 . NAG G 3 . ? 33.581 -156.791 27.008 1.00 28.41 ? 501 NAG A O5 1 HETATM 10049 O O6 . NAG G 3 . ? 36.246 -156.493 27.438 1.00 38.55 ? 501 NAG A O6 1 HETATM 10050 O O7 . NAG G 3 . ? 29.546 -156.156 22.926 1.00 42.40 ? 501 NAG A O7 1 HETATM 10051 O O . A2G H 4 . ? 23.630 -134.355 35.644 1.00 54.71 ? 502 A2G A O 1 HETATM 10052 C C1 . A2G H 4 . ? 24.668 -134.685 34.722 1.00 52.16 ? 502 A2G A C1 1 HETATM 10053 C C2 . A2G H 4 . ? 24.655 -133.699 33.560 1.00 62.40 ? 502 A2G A C2 1 HETATM 10054 N N2 . A2G H 4 . ? 25.732 -133.998 32.637 1.00 54.04 ? 502 A2G A N2 1 HETATM 10055 C C3 . A2G H 4 . ? 24.782 -132.268 34.066 1.00 59.34 ? 502 A2G A C3 1 HETATM 10056 O O3 . A2G H 4 . ? 24.578 -131.356 32.981 1.00 66.37 ? 502 A2G A O3 1 HETATM 10057 C C4 . A2G H 4 . ? 23.757 -131.997 35.159 1.00 59.97 ? 502 A2G A C4 1 HETATM 10058 O O4 . A2G H 4 . ? 22.444 -131.974 34.588 1.00 51.92 ? 502 A2G A O4 1 HETATM 10059 C C5 . A2G H 4 . ? 23.825 -133.072 36.237 1.00 59.64 ? 502 A2G A C5 1 HETATM 10060 C C6 . A2G H 4 . ? 22.765 -132.840 37.307 1.00 61.25 ? 502 A2G A C6 1 HETATM 10061 O O6 . A2G H 4 . ? 22.931 -133.798 38.358 1.00 50.07 ? 502 A2G A O6 1 HETATM 10062 C C7 . A2G H 4 . ? 25.608 -134.941 31.707 1.00 63.17 ? 502 A2G A C7 1 HETATM 10063 O O7 . A2G H 4 . ? 24.520 -135.302 31.290 1.00 66.96 ? 502 A2G A O7 1 HETATM 10064 C C8 . A2G H 4 . ? 26.892 -135.530 31.204 1.00 58.38 ? 502 A2G A C8 1 HETATM 10065 S S . SO4 I 5 . ? 19.380 -182.101 49.145 1.00 87.14 ? 503 SO4 A S 1 HETATM 10066 O O1 . SO4 I 5 . ? 18.651 -183.361 49.037 1.00 92.07 ? 503 SO4 A O1 1 HETATM 10067 O O2 . SO4 I 5 . ? 19.111 -181.280 47.967 1.00 86.55 ? 503 SO4 A O2 1 HETATM 10068 O O3 . SO4 I 5 . ? 20.813 -182.373 49.228 1.00 50.75 ? 503 SO4 A O3 1 HETATM 10069 O O4 . SO4 I 5 . ? 18.944 -181.390 50.344 1.00 66.19 ? 503 SO4 A O4 1 HETATM 10070 S S . SO4 J 5 . ? 17.492 -140.706 47.548 1.00 88.99 ? 504 SO4 A S 1 HETATM 10071 O O1 . SO4 J 5 . ? 17.001 -142.080 47.625 1.00 77.60 ? 504 SO4 A O1 1 HETATM 10072 O O2 . SO4 J 5 . ? 17.270 -140.183 46.202 1.00 56.80 ? 504 SO4 A O2 1 HETATM 10073 O O3 . SO4 J 5 . ? 18.920 -140.684 47.850 1.00 53.58 ? 504 SO4 A O3 1 HETATM 10074 O O4 . SO4 J 5 . ? 16.777 -139.880 48.517 1.00 91.76 ? 504 SO4 A O4 1 HETATM 10075 C C1 . NAG K 3 . ? 16.845 -98.078 42.717 1.00 32.71 ? 501 NAG C C1 1 HETATM 10076 C C2 . NAG K 3 . ? 15.515 -97.415 43.087 1.00 42.22 ? 501 NAG C C2 1 HETATM 10077 C C3 . NAG K 3 . ? 14.977 -96.617 41.900 1.00 43.05 ? 501 NAG C C3 1 HETATM 10078 C C4 . NAG K 3 . ? 16.029 -95.638 41.395 1.00 43.21 ? 501 NAG C C4 1 HETATM 10079 C C5 . NAG K 3 . ? 17.317 -96.387 41.074 1.00 43.48 ? 501 NAG C C5 1 HETATM 10080 C C6 . NAG K 3 . ? 18.447 -95.473 40.658 1.00 34.61 ? 501 NAG C C6 1 HETATM 10081 C C7 . NAG K 3 . ? 14.150 -98.629 44.766 1.00 38.72 ? 501 NAG C C7 1 HETATM 10082 C C8 . NAG K 3 . ? 14.774 -97.760 45.817 1.00 33.54 ? 501 NAG C C8 1 HETATM 10083 N N2 . NAG K 3 . ? 14.542 -98.417 43.501 1.00 43.52 ? 501 NAG C N2 1 HETATM 10084 O O3 . NAG K 3 . ? 13.804 -95.914 42.295 1.00 55.45 ? 501 NAG C O3 1 HETATM 10085 O O4 . NAG K 3 . ? 15.563 -94.969 40.227 1.00 45.33 ? 501 NAG C O4 1 HETATM 10086 O O5 . NAG K 3 . ? 17.764 -97.085 42.245 1.00 34.85 ? 501 NAG C O5 1 HETATM 10087 O O6 . NAG K 3 . ? 18.919 -94.693 41.748 1.00 42.61 ? 501 NAG C O6 1 HETATM 10088 O O7 . NAG K 3 . ? 13.324 -99.492 45.049 1.00 47.11 ? 501 NAG C O7 1 HETATM 10089 S S . SO4 L 5 . ? 24.931 -121.253 15.932 1.00 78.13 ? 502 SO4 C S 1 HETATM 10090 O O1 . SO4 L 5 . ? 25.393 -120.007 15.325 1.00 59.25 ? 502 SO4 C O1 1 HETATM 10091 O O2 . SO4 L 5 . ? 24.092 -121.973 14.978 1.00 86.58 ? 502 SO4 C O2 1 HETATM 10092 O O3 . SO4 L 5 . ? 26.080 -122.081 16.291 1.00 42.66 ? 502 SO4 C O3 1 HETATM 10093 O O4 . SO4 L 5 . ? 24.159 -120.948 17.133 1.00 79.79 ? 502 SO4 C O4 1 HETATM 10094 S S . SO4 M 5 . ? 51.612 -89.590 31.319 0.45 51.10 ? 503 SO4 C S 1 HETATM 10095 O O1 . SO4 M 5 . ? 52.711 -89.234 30.427 0.45 52.67 ? 503 SO4 C O1 1 HETATM 10096 O O2 . SO4 M 5 . ? 50.361 -89.059 30.786 0.45 58.71 ? 503 SO4 C O2 1 HETATM 10097 O O3 . SO4 M 5 . ? 51.520 -91.043 31.423 0.45 47.80 ? 503 SO4 C O3 1 HETATM 10098 O O4 . SO4 M 5 . ? 51.854 -89.021 32.642 0.45 55.47 ? 503 SO4 C O4 1 HETATM 10099 C C1 . NAG N 3 . ? 11.259 -216.493 22.590 1.00 30.06 ? 501 NAG E C1 1 HETATM 10100 C C2 . NAG N 3 . ? 11.667 -217.927 22.957 1.00 41.60 ? 501 NAG E C2 1 HETATM 10101 C C3 . NAG N 3 . ? 13.167 -217.996 23.234 1.00 37.91 ? 501 NAG E C3 1 HETATM 10102 C C4 . NAG N 3 . ? 13.955 -217.403 22.072 1.00 36.85 ? 501 NAG E C4 1 HETATM 10103 C C5 . NAG N 3 . ? 13.454 -215.996 21.763 1.00 38.07 ? 501 NAG E C5 1 HETATM 10104 C C6 . NAG N 3 . ? 14.120 -215.381 20.554 1.00 33.52 ? 501 NAG E C6 1 HETATM 10105 C C7 . NAG N 3 . ? 9.845 -219.189 24.086 1.00 36.86 ? 501 NAG E C7 1 HETATM 10106 C C8 . NAG N 3 . ? 9.380 -219.632 22.732 1.00 41.47 ? 501 NAG E C8 1 HETATM 10107 N N2 . NAG N 3 . ? 10.921 -218.389 24.126 1.00 31.83 ? 501 NAG E N2 1 HETATM 10108 O O3 . NAG N 3 . ? 13.542 -219.353 23.434 1.00 56.86 ? 501 NAG E O3 1 HETATM 10109 O O4 . NAG N 3 . ? 15.341 -217.350 22.393 1.00 45.20 ? 501 NAG E O4 1 HETATM 10110 O O5 . NAG N 3 . ? 12.050 -216.043 21.482 1.00 31.08 ? 501 NAG E O5 1 HETATM 10111 O O6 . NAG N 3 . ? 13.616 -215.927 19.342 1.00 39.98 ? 501 NAG E O6 1 HETATM 10112 O O7 . NAG N 3 . ? 9.268 -219.540 25.113 1.00 47.28 ? 501 NAG E O7 1 HETATM 10113 S S . SO4 O 5 . ? 15.801 -184.801 39.598 1.00 72.27 ? 502 SO4 E S 1 HETATM 10114 O O1 . SO4 O 5 . ? 14.709 -183.995 39.056 1.00 51.86 ? 502 SO4 E O1 1 HETATM 10115 O O2 . SO4 O 5 . ? 16.855 -184.929 38.596 1.00 67.59 ? 502 SO4 E O2 1 HETATM 10116 O O3 . SO4 O 5 . ? 15.300 -186.127 39.949 1.00 68.86 ? 502 SO4 E O3 1 HETATM 10117 O O4 . SO4 O 5 . ? 16.342 -184.154 40.790 1.00 74.75 ? 502 SO4 E O4 1 HETATM 10118 O O . HOH P 6 . ? 38.331 -135.931 52.330 1.00 38.68 ? 601 HOH A O 1 HETATM 10119 O O . HOH P 6 . ? 23.432 -184.067 56.541 1.00 36.58 ? 602 HOH A O 1 HETATM 10120 O O . HOH P 6 . ? 20.545 -185.261 66.258 1.00 34.22 ? 603 HOH A O 1 HETATM 10121 O O . HOH P 6 . ? 26.916 -176.489 68.334 1.00 24.87 ? 604 HOH A O 1 HETATM 10122 O O . HOH P 6 . ? 35.984 -146.880 75.863 1.00 32.13 ? 605 HOH A O 1 HETATM 10123 O O . HOH P 6 . ? 27.677 -178.456 64.688 1.00 34.78 ? 606 HOH A O 1 HETATM 10124 O O . HOH P 6 . ? 29.106 -144.196 68.464 1.00 28.40 ? 607 HOH A O 1 HETATM 10125 O O . HOH P 6 . ? 26.995 -147.817 64.239 1.00 27.93 ? 608 HOH A O 1 HETATM 10126 O O . HOH P 6 . ? 19.615 -176.976 68.216 1.00 25.72 ? 609 HOH A O 1 HETATM 10127 O O . HOH P 6 . ? 14.614 -138.920 6.105 1.00 37.36 ? 610 HOH A O 1 HETATM 10128 O O . HOH P 6 . ? 6.440 -152.705 8.707 1.00 38.37 ? 611 HOH A O 1 HETATM 10129 O O . HOH P 6 . ? 7.989 -136.209 17.311 1.00 42.24 ? 612 HOH A O 1 HETATM 10130 O O . HOH P 6 . ? 27.375 -174.241 69.872 1.00 34.74 ? 613 HOH A O 1 HETATM 10131 O O . HOH P 6 . ? 27.093 -146.540 69.018 1.00 45.49 ? 614 HOH A O 1 HETATM 10132 O O . HOH P 6 . ? 27.932 -162.413 29.045 1.00 17.36 ? 615 HOH A O 1 HETATM 10133 O O . HOH P 6 . ? 11.097 -151.029 36.313 1.00 18.54 ? 616 HOH A O 1 HETATM 10134 O O . HOH P 6 . ? 20.276 -164.849 23.401 1.00 24.24 ? 617 HOH A O 1 HETATM 10135 O O . HOH P 6 . ? 12.305 -153.513 52.368 1.00 29.80 ? 618 HOH A O 1 HETATM 10136 O O . HOH P 6 . ? 18.717 -161.786 55.225 1.00 19.90 ? 619 HOH A O 1 HETATM 10137 O O . HOH P 6 . ? 10.810 -145.840 23.701 1.00 24.14 ? 620 HOH A O 1 HETATM 10138 O O . HOH P 6 . ? 17.731 -151.436 44.042 1.00 21.90 ? 621 HOH A O 1 HETATM 10139 O O . HOH P 6 . ? 12.327 -152.255 48.919 1.00 30.44 ? 622 HOH A O 1 HETATM 10140 O O . HOH P 6 . ? 22.492 -166.814 71.032 1.00 31.40 ? 623 HOH A O 1 HETATM 10141 O O . HOH P 6 . ? 34.881 -164.291 38.169 1.00 24.25 ? 624 HOH A O 1 HETATM 10142 O O . HOH P 6 . ? 18.554 -157.711 38.556 1.00 13.31 ? 625 HOH A O 1 HETATM 10143 O O . HOH P 6 . ? 8.285 -159.339 20.209 1.00 32.97 ? 626 HOH A O 1 HETATM 10144 O O . HOH P 6 . ? 24.146 -161.416 66.135 1.00 22.06 ? 627 HOH A O 1 HETATM 10145 O O . HOH P 6 . ? 20.029 -163.512 61.489 1.00 18.53 ? 628 HOH A O 1 HETATM 10146 O O . HOH P 6 . ? 15.695 -156.872 46.428 1.00 17.27 ? 629 HOH A O 1 HETATM 10147 O O . HOH P 6 . ? 28.718 -168.497 35.717 1.00 24.07 ? 630 HOH A O 1 HETATM 10148 O O . HOH P 6 . ? 30.749 -155.747 43.363 1.00 14.08 ? 631 HOH A O 1 HETATM 10149 O O . HOH P 6 . ? 21.340 -177.053 62.091 1.00 22.44 ? 632 HOH A O 1 HETATM 10150 O O . HOH P 6 . ? 37.894 -163.420 57.466 1.00 29.87 ? 633 HOH A O 1 HETATM 10151 O O . HOH P 6 . ? 14.385 -156.727 16.565 1.00 28.30 ? 634 HOH A O 1 HETATM 10152 O O . HOH P 6 . ? 8.364 -148.752 29.627 1.00 26.48 ? 635 HOH A O 1 HETATM 10153 O O . HOH P 6 . ? 6.352 -154.543 38.526 1.00 22.63 ? 636 HOH A O 1 HETATM 10154 O O . HOH P 6 . ? 18.439 -157.169 55.851 1.00 27.24 ? 637 HOH A O 1 HETATM 10155 O O . HOH P 6 . ? 20.431 -172.171 49.649 1.00 29.94 ? 638 HOH A O 1 HETATM 10156 O O . HOH P 6 . ? 18.440 -153.164 7.913 1.00 22.87 ? 639 HOH A O 1 HETATM 10157 O O . HOH P 6 . ? 15.388 -145.121 31.345 1.00 19.23 ? 640 HOH A O 1 HETATM 10158 O O . HOH P 6 . ? 38.427 -167.429 43.803 1.00 31.34 ? 641 HOH A O 1 HETATM 10159 O O . HOH P 6 . ? 27.195 -161.026 68.047 1.00 29.15 ? 642 HOH A O 1 HETATM 10160 O O . HOH P 6 . ? 22.381 -164.764 69.177 1.00 27.65 ? 643 HOH A O 1 HETATM 10161 O O . HOH P 6 . ? 33.444 -147.528 41.550 1.00 24.19 ? 644 HOH A O 1 HETATM 10162 O O . HOH P 6 . ? 35.622 -157.820 48.583 1.00 21.70 ? 645 HOH A O 1 HETATM 10163 O O . HOH P 6 . ? 2.299 -163.591 31.261 1.00 37.09 ? 646 HOH A O 1 HETATM 10164 O O . HOH P 6 . ? 25.493 -138.797 47.253 1.00 30.92 ? 647 HOH A O 1 HETATM 10165 O O . HOH P 6 . ? 27.638 -159.816 43.841 1.00 21.02 ? 648 HOH A O 1 HETATM 10166 O O . HOH P 6 . ? 25.933 -155.813 10.312 1.00 35.81 ? 649 HOH A O 1 HETATM 10167 O O . HOH P 6 . ? 31.238 -170.115 36.246 1.00 39.21 ? 650 HOH A O 1 HETATM 10168 O O . HOH P 6 . ? 34.016 -149.626 40.082 1.00 26.48 ? 651 HOH A O 1 HETATM 10169 O O . HOH P 6 . ? 16.572 -157.924 62.360 1.00 38.37 ? 652 HOH A O 1 HETATM 10170 O O . HOH P 6 . ? 10.329 -161.525 44.774 1.00 34.61 ? 653 HOH A O 1 HETATM 10171 O O . HOH P 6 . ? 27.602 -152.870 25.588 1.00 28.10 ? 654 HOH A O 1 HETATM 10172 O O . HOH P 6 . ? 40.364 -153.195 69.407 1.00 42.17 ? 655 HOH A O 1 HETATM 10173 O O . HOH P 6 . ? 19.697 -176.947 51.289 1.00 32.56 ? 656 HOH A O 1 HETATM 10174 O O . HOH P 6 . ? 13.875 -138.834 12.058 1.00 26.23 ? 657 HOH A O 1 HETATM 10175 O O . HOH P 6 . ? 30.896 -133.526 43.226 1.00 30.50 ? 658 HOH A O 1 HETATM 10176 O O . HOH P 6 . ? 10.875 -163.308 39.286 1.00 20.42 ? 659 HOH A O 1 HETATM 10177 O O . HOH P 6 . ? 21.567 -150.725 8.543 1.00 28.83 ? 660 HOH A O 1 HETATM 10178 O O . HOH P 6 . ? 16.916 -163.776 55.386 1.00 22.69 ? 661 HOH A O 1 HETATM 10179 O O . HOH P 6 . ? 25.472 -170.331 41.454 1.00 32.63 ? 662 HOH A O 1 HETATM 10180 O O . HOH P 6 . ? 5.135 -151.510 30.587 1.00 29.30 ? 663 HOH A O 1 HETATM 10181 O O . HOH P 6 . ? 32.146 -159.369 70.046 1.00 30.60 ? 664 HOH A O 1 HETATM 10182 O O . HOH P 6 . ? 21.252 -161.457 65.661 1.00 31.91 ? 665 HOH A O 1 HETATM 10183 O O . HOH P 6 . ? 1.543 -160.504 32.559 1.00 35.21 ? 666 HOH A O 1 HETATM 10184 O O . HOH P 6 . ? 19.889 -163.821 64.249 1.00 38.42 ? 667 HOH A O 1 HETATM 10185 O O . HOH P 6 . ? 10.966 -153.492 16.086 1.00 32.60 ? 668 HOH A O 1 HETATM 10186 O O . HOH P 6 . ? 9.841 -151.938 18.183 1.00 36.22 ? 669 HOH A O 1 HETATM 10187 O O . HOH P 6 . ? 31.442 -153.553 64.024 1.00 20.49 ? 670 HOH A O 1 HETATM 10188 O O . HOH P 6 . ? 31.269 -141.946 44.082 1.00 21.10 ? 671 HOH A O 1 HETATM 10189 O O . HOH P 6 . ? 15.428 -153.278 14.828 1.00 28.73 ? 672 HOH A O 1 HETATM 10190 O O . HOH P 6 . ? 38.767 -156.626 41.405 1.00 29.58 ? 673 HOH A O 1 HETATM 10191 O O . HOH P 6 . ? 6.436 -163.486 23.377 1.00 39.16 ? 674 HOH A O 1 HETATM 10192 O O . HOH P 6 . ? 27.074 -177.013 58.494 1.00 23.98 ? 675 HOH A O 1 HETATM 10193 O O . HOH P 6 . ? 12.319 -146.332 13.857 1.00 29.60 ? 676 HOH A O 1 HETATM 10194 O O . HOH P 6 . ? 18.669 -173.744 59.902 1.00 21.26 ? 677 HOH A O 1 HETATM 10195 O O . HOH P 6 . ? 29.840 -158.301 43.405 1.00 25.84 ? 678 HOH A O 1 HETATM 10196 O O . HOH P 6 . ? 23.338 -157.492 65.258 1.00 31.54 ? 679 HOH A O 1 HETATM 10197 O O . HOH P 6 . ? 21.001 -151.246 57.664 1.00 28.94 ? 680 HOH A O 1 HETATM 10198 O O . HOH P 6 . ? 47.926 -162.321 47.815 1.00 40.80 ? 681 HOH A O 1 HETATM 10199 O O . HOH P 6 . ? 24.520 -163.740 67.591 1.00 31.21 ? 682 HOH A O 1 HETATM 10200 O O . HOH P 6 . ? 20.167 -169.020 40.709 1.00 40.20 ? 683 HOH A O 1 HETATM 10201 O O . HOH P 6 . ? 29.647 -148.514 68.333 1.00 39.55 ? 684 HOH A O 1 HETATM 10202 O O . HOH P 6 . ? 30.282 -154.788 67.629 1.00 36.87 ? 685 HOH A O 1 HETATM 10203 O O . HOH P 6 . ? 22.602 -141.995 51.129 1.00 29.21 ? 686 HOH A O 1 HETATM 10204 O O . HOH P 6 . ? 36.594 -149.760 41.451 1.00 32.52 ? 687 HOH A O 1 HETATM 10205 O O . HOH P 6 . ? 29.563 -153.515 69.824 1.00 37.27 ? 688 HOH A O 1 HETATM 10206 O O . HOH P 6 . ? 31.336 -160.978 27.171 1.00 35.84 ? 689 HOH A O 1 HETATM 10207 O O . HOH P 6 . ? 15.943 -134.089 22.090 1.00 43.04 ? 690 HOH A O 1 HETATM 10208 O O . HOH P 6 . ? 25.698 -166.014 61.492 1.00 20.79 ? 691 HOH A O 1 HETATM 10209 O O . HOH P 6 . ? 25.585 -151.438 38.825 1.00 22.13 ? 692 HOH A O 1 HETATM 10210 O O . HOH P 6 . ? 37.316 -163.147 38.307 1.00 32.48 ? 693 HOH A O 1 HETATM 10211 O O . HOH P 6 . ? 21.588 -166.163 25.536 1.00 26.41 ? 694 HOH A O 1 HETATM 10212 O O . HOH P 6 . ? 26.429 -175.289 48.950 1.00 34.67 ? 695 HOH A O 1 HETATM 10213 O O . HOH P 6 . ? 10.776 -158.848 18.211 1.00 45.90 ? 696 HOH A O 1 HETATM 10214 O O . HOH P 6 . ? 13.496 -165.317 62.542 1.00 47.38 ? 697 HOH A O 1 HETATM 10215 O O . HOH P 6 . ? 28.667 -162.880 73.758 1.00 35.93 ? 698 HOH A O 1 HETATM 10216 O O . HOH P 6 . ? 22.032 -138.948 21.039 1.00 35.66 ? 699 HOH A O 1 HETATM 10217 O O . HOH P 6 . ? 22.223 -165.389 21.335 1.00 36.48 ? 700 HOH A O 1 HETATM 10218 O O . HOH P 6 . ? 32.992 -134.400 42.149 1.00 42.78 ? 701 HOH A O 1 HETATM 10219 O O . HOH P 6 . ? 28.320 -178.980 60.549 1.00 32.94 ? 702 HOH A O 1 HETATM 10220 O O . HOH P 6 . ? 23.705 -154.453 61.659 1.00 34.63 ? 703 HOH A O 1 HETATM 10221 O O . HOH P 6 . ? 24.844 -132.643 40.300 1.00 38.36 ? 704 HOH A O 1 HETATM 10222 O O . HOH P 6 . ? 22.565 -146.626 34.867 1.00 36.92 ? 705 HOH A O 1 HETATM 10223 O O . HOH P 6 . ? 23.231 -142.434 16.733 1.00 35.35 ? 706 HOH A O 1 HETATM 10224 O O . HOH P 6 . ? 39.582 -142.999 47.043 1.00 36.40 ? 707 HOH A O 1 HETATM 10225 O O . HOH P 6 . ? 39.726 -145.779 47.320 1.00 33.68 ? 708 HOH A O 1 HETATM 10226 O O . HOH P 6 . ? 23.658 -170.127 39.560 1.00 39.87 ? 709 HOH A O 1 HETATM 10227 O O . HOH P 6 . ? 27.344 -136.763 47.134 1.00 45.72 ? 710 HOH A O 1 HETATM 10228 O O . HOH P 6 . ? 7.451 -154.284 42.838 1.00 31.50 ? 711 HOH A O 1 HETATM 10229 O O . HOH P 6 . ? 8.841 -146.330 21.291 1.00 45.24 ? 712 HOH A O 1 HETATM 10230 O O . HOH P 6 . ? 26.718 -159.230 22.193 1.00 29.00 ? 713 HOH A O 1 HETATM 10231 O O . HOH P 6 . ? 5.131 -161.857 20.989 1.00 42.69 ? 714 HOH A O 1 HETATM 10232 O O . HOH P 6 . ? 38.504 -163.770 35.873 1.00 32.01 ? 715 HOH A O 1 HETATM 10233 O O . HOH P 6 . ? 31.475 -155.222 71.031 1.00 37.02 ? 716 HOH A O 1 HETATM 10234 O O . HOH P 6 . ? 28.897 -160.839 24.301 1.00 33.21 ? 717 HOH A O 1 HETATM 10235 O O . HOH P 6 . ? 26.391 -159.912 10.898 1.00 38.25 ? 718 HOH A O 1 HETATM 10236 O O . HOH P 6 . ? 28.220 -150.577 12.874 1.00 38.52 ? 719 HOH A O 1 HETATM 10237 O O . HOH P 6 . ? 28.311 -160.356 30.533 1.00 20.59 ? 720 HOH A O 1 HETATM 10238 O O . HOH P 6 . ? 14.580 -149.773 42.733 1.00 23.17 ? 721 HOH A O 1 HETATM 10239 O O . HOH P 6 . ? 15.707 -151.925 43.064 1.00 33.36 ? 722 HOH A O 1 HETATM 10240 O O . HOH P 6 . ? 12.169 -149.351 43.148 1.00 39.33 ? 723 HOH A O 1 HETATM 10241 O O . HOH P 6 . ? 9.167 -150.851 38.169 1.00 28.88 ? 724 HOH A O 1 HETATM 10242 O O . HOH P 6 . ? 11.138 -172.955 64.260 1.00 45.34 ? 725 HOH A O 1 HETATM 10243 O O . HOH P 6 . ? 20.618 -164.249 66.517 1.00 33.33 ? 726 HOH A O 1 HETATM 10244 O O . HOH P 6 . ? 14.930 -162.542 68.883 1.00 43.35 ? 727 HOH A O 1 HETATM 10245 O O . HOH P 6 . ? 18.904 -154.288 59.495 1.00 35.22 ? 728 HOH A O 1 HETATM 10246 O O . HOH P 6 . ? 33.076 -156.822 69.287 1.00 31.91 ? 729 HOH A O 1 HETATM 10247 O O . HOH P 6 . ? 27.530 -150.379 69.177 1.00 47.61 ? 730 HOH A O 1 HETATM 10248 O O . HOH P 6 . ? 26.347 -152.155 69.956 1.00 51.32 ? 731 HOH A O 1 HETATM 10249 O O . HOH P 6 . ? 26.408 -154.163 70.921 1.00 51.83 ? 732 HOH A O 1 HETATM 10250 O O . HOH P 6 . ? 28.529 -162.202 51.778 1.00 23.43 ? 733 HOH A O 1 HETATM 10251 O O . HOH P 6 . ? 43.183 -142.530 48.575 1.00 37.80 ? 734 HOH A O 1 HETATM 10252 O O . HOH P 6 . ? 37.291 -142.954 41.118 1.00 35.24 ? 735 HOH A O 1 HETATM 10253 O O . HOH P 6 . ? 29.969 -133.297 48.488 1.00 37.77 ? 736 HOH A O 1 HETATM 10254 O O . HOH P 6 . ? 45.576 -153.905 46.499 1.00 43.89 ? 737 HOH A O 1 HETATM 10255 O O . HOH P 6 . ? 19.527 -178.441 53.742 1.00 36.15 ? 738 HOH A O 1 HETATM 10256 O O . HOH P 6 . ? 10.161 -161.558 48.572 1.00 47.25 ? 739 HOH A O 1 HETATM 10257 O O . HOH P 6 . ? 33.935 -150.613 36.139 1.00 43.49 ? 740 HOH A O 1 HETATM 10258 O O . HOH P 6 . ? 19.440 -151.701 32.676 1.00 21.71 ? 741 HOH A O 1 HETATM 10259 O O . HOH P 6 . ? 20.666 -152.533 34.819 1.00 20.37 ? 742 HOH A O 1 HETATM 10260 O O . HOH P 6 . ? 18.208 -153.204 35.991 1.00 13.24 ? 743 HOH A O 1 HETATM 10261 O O . HOH P 6 . ? 6.312 -154.145 24.941 1.00 26.40 ? 744 HOH A O 1 HETATM 10262 O O . HOH P 6 . ? 20.785 -167.380 19.416 1.00 47.54 ? 745 HOH A O 1 HETATM 10263 O O . HOH P 6 . ? 19.902 -166.919 16.822 1.00 46.01 ? 746 HOH A O 1 HETATM 10264 O O . HOH P 6 . ? 4.343 -154.568 35.040 1.00 28.78 ? 747 HOH A O 1 HETATM 10265 O O . HOH P 6 . ? 20.190 -135.060 16.409 1.00 38.84 ? 748 HOH A O 1 HETATM 10266 O O . HOH P 6 . ? 15.887 -151.134 2.433 1.00 32.31 ? 749 HOH A O 1 HETATM 10267 O O . HOH P 6 . ? 18.300 -147.416 9.510 1.00 37.46 ? 750 HOH A O 1 HETATM 10268 O O . HOH P 6 . ? 17.940 -145.712 32.832 1.00 28.87 ? 751 HOH A O 1 HETATM 10269 O O . HOH P 6 . ? 35.757 -161.249 32.348 1.00 40.13 ? 752 HOH A O 1 HETATM 10270 O O . HOH P 6 . ? 23.585 -135.784 45.401 1.00 42.10 ? 753 HOH A O 1 HETATM 10271 O O . HOH P 6 . ? 11.486 -149.371 48.095 1.00 54.39 ? 754 HOH A O 1 HETATM 10272 O O . HOH P 6 . ? 43.119 -150.484 51.056 1.00 31.64 ? 755 HOH A O 1 HETATM 10273 O O . HOH P 6 . ? 3.845 -153.901 37.014 1.00 31.47 ? 756 HOH A O 1 HETATM 10274 O O . HOH P 6 . ? 20.237 -142.258 50.710 1.00 30.12 ? 757 HOH A O 1 HETATM 10275 O O . HOH P 6 . ? 17.630 -159.168 54.207 1.00 31.35 ? 758 HOH A O 1 HETATM 10276 O O . HOH P 6 . ? 16.685 -154.223 60.024 1.00 54.30 ? 759 HOH A O 1 HETATM 10277 O O . HOH P 6 . ? 17.548 -162.177 68.883 1.00 44.68 ? 760 HOH A O 1 HETATM 10278 O O . HOH P 6 . ? 3.594 -151.659 37.495 1.00 47.15 ? 761 HOH A O 1 HETATM 10279 O O . HOH P 6 . ? 15.119 -144.738 28.682 1.00 33.26 ? 762 HOH A O 1 HETATM 10280 O O . HOH P 6 . ? 11.990 -150.959 51.754 1.00 50.56 ? 763 HOH A O 1 HETATM 10281 O O . HOH P 6 . ? 24.594 -154.717 64.030 1.00 40.79 ? 764 HOH A O 1 HETATM 10282 O O . HOH P 6 . ? 24.511 -152.197 65.248 1.00 38.92 ? 765 HOH A O 1 HETATM 10283 O O . HOH Q 6 . ? 51.604 -92.509 33.260 1.00 43.54 ? 601 HOH C O 1 HETATM 10284 O O . HOH Q 6 . ? 32.012 -120.716 11.102 1.00 34.48 ? 602 HOH C O 1 HETATM 10285 O O . HOH Q 6 . ? 47.891 -89.177 30.077 1.00 43.33 ? 603 HOH C O 1 HETATM 10286 O O . HOH Q 6 . ? 49.245 -115.182 48.411 1.00 41.73 ? 604 HOH C O 1 HETATM 10287 O O . HOH Q 6 . ? 17.001 -119.237 59.233 1.00 36.94 ? 605 HOH C O 1 HETATM 10288 O O . HOH Q 6 . ? 53.349 -124.959 14.547 1.00 31.63 ? 606 HOH C O 1 HETATM 10289 O O . HOH Q 6 . ? 5.579 -122.468 44.641 1.00 30.36 ? 607 HOH C O 1 HETATM 10290 O O . HOH Q 6 . ? 63.757 -107.354 30.844 1.00 34.68 ? 608 HOH C O 1 HETATM 10291 O O . HOH Q 6 . ? 48.684 -118.538 47.001 1.00 43.37 ? 609 HOH C O 1 HETATM 10292 O O . HOH Q 6 . ? 16.907 -119.918 55.470 1.00 28.17 ? 610 HOH C O 1 HETATM 10293 O O . HOH Q 6 . ? 46.067 -119.950 13.645 1.00 26.54 ? 611 HOH C O 1 HETATM 10294 O O . HOH Q 6 . ? 43.990 -126.754 14.981 1.00 29.55 ? 612 HOH C O 1 HETATM 10295 O O . HOH Q 6 . ? 62.193 -103.769 36.653 1.00 33.49 ? 613 HOH C O 1 HETATM 10296 O O . HOH Q 6 . ? 21.747 -113.426 56.352 1.00 26.57 ? 614 HOH C O 1 HETATM 10297 O O . HOH Q 6 . ? 48.924 -128.709 18.922 1.00 34.37 ? 615 HOH C O 1 HETATM 10298 O O . HOH Q 6 . ? 56.690 -112.435 39.394 1.00 35.42 ? 616 HOH C O 1 HETATM 10299 O O . HOH Q 6 . ? 48.480 -120.006 15.036 1.00 28.47 ? 617 HOH C O 1 HETATM 10300 O O . HOH Q 6 . ? 3.506 -122.664 48.302 1.00 42.94 ? 618 HOH C O 1 HETATM 10301 O O . HOH Q 6 . ? 37.499 -120.877 33.004 1.00 17.90 ? 619 HOH C O 1 HETATM 10302 O O . HOH Q 6 . ? 23.432 -113.617 47.009 1.00 21.79 ? 620 HOH C O 1 HETATM 10303 O O . HOH Q 6 . ? 38.753 -123.306 16.372 1.00 21.43 ? 621 HOH C O 1 HETATM 10304 O O . HOH Q 6 . ? 30.376 -122.533 17.944 1.00 28.99 ? 622 HOH C O 1 HETATM 10305 O O . HOH Q 6 . ? 33.868 -123.421 45.374 1.00 22.77 ? 623 HOH C O 1 HETATM 10306 O O . HOH Q 6 . ? 23.135 -110.882 47.302 1.00 19.74 ? 624 HOH C O 1 HETATM 10307 O O . HOH Q 6 . ? 22.787 -120.068 50.900 1.00 21.13 ? 625 HOH C O 1 HETATM 10308 O O . HOH Q 6 . ? 29.080 -119.253 24.728 1.00 27.63 ? 626 HOH C O 1 HETATM 10309 O O . HOH Q 6 . ? 48.748 -119.597 28.621 1.00 26.84 ? 627 HOH C O 1 HETATM 10310 O O . HOH Q 6 . ? 26.223 -125.332 38.804 1.00 26.82 ? 628 HOH C O 1 HETATM 10311 O O . HOH Q 6 . ? 49.458 -120.563 26.125 1.00 31.10 ? 629 HOH C O 1 HETATM 10312 O O . HOH Q 6 . ? 31.182 -110.057 26.144 1.00 16.25 ? 630 HOH C O 1 HETATM 10313 O O . HOH Q 6 . ? 36.549 -111.025 31.002 1.00 15.58 ? 631 HOH C O 1 HETATM 10314 O O . HOH Q 6 . ? 25.265 -100.865 31.637 1.00 29.43 ? 632 HOH C O 1 HETATM 10315 O O . HOH Q 6 . ? 37.141 -116.695 15.967 1.00 20.85 ? 633 HOH C O 1 HETATM 10316 O O . HOH Q 6 . ? 43.940 -95.175 38.319 1.00 25.44 ? 634 HOH C O 1 HETATM 10317 O O . HOH Q 6 . ? 43.269 -117.357 25.390 1.00 15.72 ? 635 HOH C O 1 HETATM 10318 O O . HOH Q 6 . ? 27.961 -98.287 44.733 1.00 36.39 ? 636 HOH C O 1 HETATM 10319 O O . HOH Q 6 . ? 37.250 -124.560 20.620 1.00 19.51 ? 637 HOH C O 1 HETATM 10320 O O . HOH Q 6 . ? 15.917 -104.136 38.096 1.00 23.95 ? 638 HOH C O 1 HETATM 10321 O O . HOH Q 6 . ? 26.275 -98.526 31.811 1.00 30.70 ? 639 HOH C O 1 HETATM 10322 O O . HOH Q 6 . ? 30.864 -120.146 41.053 1.00 21.34 ? 640 HOH C O 1 HETATM 10323 O O . HOH Q 6 . ? 40.453 -108.069 54.770 1.00 32.54 ? 641 HOH C O 1 HETATM 10324 O O . HOH Q 6 . ? 19.914 -106.633 30.105 1.00 21.65 ? 642 HOH C O 1 HETATM 10325 O O . HOH Q 6 . ? 36.486 -123.226 31.613 1.00 25.25 ? 643 HOH C O 1 HETATM 10326 O O . HOH Q 6 . ? 29.931 -99.722 26.091 1.00 23.85 ? 644 HOH C O 1 HETATM 10327 O O . HOH Q 6 . ? 37.199 -102.390 34.113 1.00 22.65 ? 645 HOH C O 1 HETATM 10328 O O . HOH Q 6 . ? 32.061 -105.007 38.943 1.00 16.63 ? 646 HOH C O 1 HETATM 10329 O O . HOH Q 6 . ? 21.272 -111.110 49.074 1.00 21.72 ? 647 HOH C O 1 HETATM 10330 O O . HOH Q 6 . ? 32.044 -96.997 36.632 1.00 26.67 ? 648 HOH C O 1 HETATM 10331 O O . HOH Q 6 . ? 49.138 -119.350 33.095 1.00 37.49 ? 649 HOH C O 1 HETATM 10332 O O . HOH Q 6 . ? 39.482 -120.790 37.101 1.00 26.73 ? 650 HOH C O 1 HETATM 10333 O O . HOH Q 6 . ? 36.373 -124.577 43.239 1.00 37.46 ? 651 HOH C O 1 HETATM 10334 O O . HOH Q 6 . ? 18.318 -103.814 39.374 1.00 25.75 ? 652 HOH C O 1 HETATM 10335 O O . HOH Q 6 . ? 42.802 -122.270 29.309 1.00 22.82 ? 653 HOH C O 1 HETATM 10336 O O . HOH Q 6 . ? 24.048 -115.058 41.961 1.00 18.26 ? 654 HOH C O 1 HETATM 10337 O O . HOH Q 6 . ? 55.305 -111.714 29.512 1.00 29.68 ? 655 HOH C O 1 HETATM 10338 O O . HOH Q 6 . ? 8.201 -109.737 39.838 1.00 28.66 ? 656 HOH C O 1 HETATM 10339 O O . HOH Q 6 . ? 40.872 -93.500 27.578 1.00 32.06 ? 657 HOH C O 1 HETATM 10340 O O . HOH Q 6 . ? 30.206 -108.669 35.919 1.00 19.83 ? 658 HOH C O 1 HETATM 10341 O O . HOH Q 6 . ? 38.582 -116.543 13.309 1.00 27.96 ? 659 HOH C O 1 HETATM 10342 O O . HOH Q 6 . ? 34.268 -100.488 46.434 1.00 26.32 ? 660 HOH C O 1 HETATM 10343 O O . HOH Q 6 . ? 41.680 -96.213 44.511 1.00 28.76 ? 661 HOH C O 1 HETATM 10344 O O . HOH Q 6 . ? 23.453 -111.622 27.695 1.00 27.87 ? 662 HOH C O 1 HETATM 10345 O O . HOH Q 6 . ? 24.386 -116.896 27.745 1.00 32.19 ? 663 HOH C O 1 HETATM 10346 O O . HOH Q 6 . ? 45.000 -123.457 28.019 1.00 36.53 ? 664 HOH C O 1 HETATM 10347 O O . HOH Q 6 . ? 42.305 -95.794 47.168 1.00 37.11 ? 665 HOH C O 1 HETATM 10348 O O . HOH Q 6 . ? 30.983 -116.538 46.214 1.00 26.87 ? 666 HOH C O 1 HETATM 10349 O O . HOH Q 6 . ? 28.130 -107.457 45.573 1.00 28.53 ? 667 HOH C O 1 HETATM 10350 O O . HOH Q 6 . ? 51.395 -117.319 27.648 1.00 30.53 ? 668 HOH C O 1 HETATM 10351 O O . HOH Q 6 . ? 50.594 -123.791 22.888 1.00 31.48 ? 669 HOH C O 1 HETATM 10352 O O . HOH Q 6 . ? 22.117 -114.516 32.706 1.00 26.14 ? 670 HOH C O 1 HETATM 10353 O O . HOH Q 6 . ? 27.982 -125.967 37.113 1.00 34.35 ? 671 HOH C O 1 HETATM 10354 O O . HOH Q 6 . ? 34.038 -97.738 43.540 1.00 30.16 ? 672 HOH C O 1 HETATM 10355 O O . HOH Q 6 . ? 22.021 -107.494 26.556 1.00 34.33 ? 673 HOH C O 1 HETATM 10356 O O . HOH Q 6 . ? 32.744 -98.451 22.113 1.00 47.22 ? 674 HOH C O 1 HETATM 10357 O O . HOH Q 6 . ? 16.641 -101.267 47.920 1.00 40.76 ? 675 HOH C O 1 HETATM 10358 O O . HOH Q 6 . ? 32.417 -106.365 56.063 1.00 35.10 ? 676 HOH C O 1 HETATM 10359 O O . HOH Q 6 . ? 41.396 -102.549 57.790 1.00 46.09 ? 677 HOH C O 1 HETATM 10360 O O . HOH Q 6 . ? 21.306 -98.967 25.883 1.00 40.83 ? 678 HOH C O 1 HETATM 10361 O O . HOH Q 6 . ? 51.635 -110.857 34.683 1.00 21.06 ? 679 HOH C O 1 HETATM 10362 O O . HOH Q 6 . ? 56.205 -118.281 24.104 1.00 31.51 ? 680 HOH C O 1 HETATM 10363 O O . HOH Q 6 . ? 30.861 -106.238 36.837 1.00 18.20 ? 681 HOH C O 1 HETATM 10364 O O . HOH Q 6 . ? 47.558 -122.310 29.704 1.00 34.99 ? 682 HOH C O 1 HETATM 10365 O O . HOH Q 6 . ? 39.860 -92.754 42.981 1.00 36.73 ? 683 HOH C O 1 HETATM 10366 O O . HOH Q 6 . ? 35.418 -93.856 33.594 1.00 37.59 ? 684 HOH C O 1 HETATM 10367 O O . HOH Q 6 . ? 37.080 -121.186 36.094 1.00 38.98 ? 685 HOH C O 1 HETATM 10368 O O . HOH Q 6 . ? 22.457 -125.900 48.152 1.00 28.45 ? 686 HOH C O 1 HETATM 10369 O O . HOH Q 6 . ? 28.788 -106.706 52.841 1.00 37.48 ? 687 HOH C O 1 HETATM 10370 O O . HOH Q 6 . ? 19.315 -109.339 30.088 1.00 38.39 ? 688 HOH C O 1 HETATM 10371 O O . HOH Q 6 . ? 32.211 -99.742 44.826 1.00 28.12 ? 689 HOH C O 1 HETATM 10372 O O . HOH Q 6 . ? 30.066 -126.948 38.046 1.00 40.39 ? 690 HOH C O 1 HETATM 10373 O O . HOH Q 6 . ? 13.226 -99.732 40.968 1.00 39.88 ? 691 HOH C O 1 HETATM 10374 O O . HOH Q 6 . ? 12.409 -101.867 40.575 1.00 32.34 ? 692 HOH C O 1 HETATM 10375 O O . HOH Q 6 . ? 43.066 -98.142 19.394 1.00 41.88 ? 693 HOH C O 1 HETATM 10376 O O . HOH Q 6 . ? 38.981 -132.347 22.130 1.00 35.87 ? 694 HOH C O 1 HETATM 10377 O O . HOH Q 6 . ? 49.701 -122.919 25.365 1.00 27.43 ? 695 HOH C O 1 HETATM 10378 O O . HOH Q 6 . ? 44.665 -124.983 34.982 1.00 47.49 ? 696 HOH C O 1 HETATM 10379 O O . HOH Q 6 . ? 55.667 -122.025 18.104 1.00 41.98 ? 697 HOH C O 1 HETATM 10380 O O . HOH Q 6 . ? 42.004 -118.279 12.700 1.00 33.69 ? 698 HOH C O 1 HETATM 10381 O O . HOH Q 6 . ? 56.165 -117.499 35.645 1.00 48.33 ? 699 HOH C O 1 HETATM 10382 O O . HOH Q 6 . ? 44.177 -92.589 46.092 1.00 38.45 ? 700 HOH C O 1 HETATM 10383 O O . HOH Q 6 . ? 38.020 -102.202 51.248 1.00 28.39 ? 701 HOH C O 1 HETATM 10384 O O . HOH Q 6 . ? 44.347 -104.683 57.808 1.00 51.97 ? 702 HOH C O 1 HETATM 10385 O O . HOH Q 6 . ? 36.416 -95.749 49.558 1.00 38.41 ? 703 HOH C O 1 HETATM 10386 O O . HOH Q 6 . ? 39.470 -91.316 35.717 1.00 39.29 ? 704 HOH C O 1 HETATM 10387 O O . HOH Q 6 . ? 37.711 -91.767 26.727 1.00 38.10 ? 705 HOH C O 1 HETATM 10388 O O . HOH Q 6 . ? 46.489 -91.232 26.592 1.00 42.13 ? 706 HOH C O 1 HETATM 10389 O O . HOH Q 6 . ? 37.420 -103.448 25.582 1.00 27.33 ? 707 HOH C O 1 HETATM 10390 O O . HOH Q 6 . ? 40.395 -105.833 26.885 1.00 39.43 ? 708 HOH C O 1 HETATM 10391 O O . HOH Q 6 . ? 36.856 -115.823 56.247 1.00 48.23 ? 709 HOH C O 1 HETATM 10392 O O . HOH Q 6 . ? 38.686 -115.460 54.832 1.00 40.05 ? 710 HOH C O 1 HETATM 10393 O O . HOH Q 6 . ? 37.170 -124.081 46.637 1.00 55.86 ? 711 HOH C O 1 HETATM 10394 O O . HOH Q 6 . ? 26.403 -118.799 25.374 1.00 40.38 ? 712 HOH C O 1 HETATM 10395 O O . HOH Q 6 . ? 28.855 -114.141 20.489 1.00 37.74 ? 713 HOH C O 1 HETATM 10396 O O . HOH Q 6 . ? 28.759 -121.490 19.883 1.00 26.86 ? 714 HOH C O 1 HETATM 10397 O O . HOH Q 6 . ? 26.768 -118.254 14.424 1.00 34.97 ? 715 HOH C O 1 HETATM 10398 O O . HOH Q 6 . ? 30.701 -125.166 16.829 1.00 44.38 ? 716 HOH C O 1 HETATM 10399 O O . HOH Q 6 . ? 24.272 -113.159 14.599 1.00 51.92 ? 717 HOH C O 1 HETATM 10400 O O . HOH Q 6 . ? 42.752 -94.069 43.055 1.00 37.72 ? 718 HOH C O 1 HETATM 10401 O O . HOH Q 6 . ? 43.901 -93.578 40.636 1.00 38.22 ? 719 HOH C O 1 HETATM 10402 O O . HOH Q 6 . ? 27.744 -109.324 54.580 1.00 44.75 ? 720 HOH C O 1 HETATM 10403 O O . HOH Q 6 . ? 23.296 -111.526 55.003 1.00 34.29 ? 721 HOH C O 1 HETATM 10404 O O . HOH Q 6 . ? 20.637 -127.548 49.951 1.00 34.86 ? 722 HOH C O 1 HETATM 10405 O O . HOH Q 6 . ? 4.763 -121.155 49.651 1.00 43.57 ? 723 HOH C O 1 HETATM 10406 O O . HOH Q 6 . ? 9.982 -121.359 52.666 1.00 33.08 ? 724 HOH C O 1 HETATM 10407 O O . HOH Q 6 . ? 29.826 -118.597 48.942 1.00 30.51 ? 725 HOH C O 1 HETATM 10408 O O . HOH Q 6 . ? 28.889 -102.087 62.993 1.00 59.50 ? 726 HOH C O 1 HETATM 10409 O O . HOH Q 6 . ? 6.548 -106.702 68.826 1.00 41.87 ? 727 HOH C O 1 HETATM 10410 O O . HOH Q 6 . ? 4.886 -110.485 62.076 1.00 46.05 ? 728 HOH C O 1 HETATM 10411 O O . HOH Q 6 . ? 24.110 -101.623 53.398 1.00 48.37 ? 729 HOH C O 1 HETATM 10412 O O . HOH Q 6 . ? 4.809 -118.738 48.974 1.00 37.01 ? 730 HOH C O 1 HETATM 10413 O O . HOH Q 6 . ? 9.912 -109.503 37.501 1.00 30.63 ? 731 HOH C O 1 HETATM 10414 O O . HOH Q 6 . ? 43.463 -104.328 25.725 1.00 37.67 ? 732 HOH C O 1 HETATM 10415 O O . HOH Q 6 . ? 18.650 -126.559 49.909 1.00 33.11 ? 733 HOH C O 1 HETATM 10416 O O . HOH R 6 . ? 2.350 -174.720 36.249 1.00 37.38 ? 601 HOH E O 1 HETATM 10417 O O . HOH R 6 . ? -1.140 -173.100 35.587 1.00 39.06 ? 602 HOH E O 1 HETATM 10418 O O . HOH R 6 . ? -2.511 -191.238 -3.090 1.00 40.60 ? 603 HOH E O 1 HETATM 10419 O O . HOH R 6 . ? -7.704 -181.875 3.114 1.00 29.87 ? 604 HOH E O 1 HETATM 10420 O O . HOH R 6 . ? -6.111 -184.304 8.308 1.00 25.75 ? 605 HOH E O 1 HETATM 10421 O O . HOH R 6 . ? 10.988 -180.288 37.970 1.00 29.83 ? 606 HOH E O 1 HETATM 10422 O O . HOH R 6 . ? -3.381 -200.873 -3.359 1.00 36.57 ? 607 HOH E O 1 HETATM 10423 O O . HOH R 6 . ? 0.019 -202.543 43.957 1.00 42.34 ? 608 HOH E O 1 HETATM 10424 O O . HOH R 6 . ? -8.022 -193.429 -1.792 1.00 47.99 ? 609 HOH E O 1 HETATM 10425 O O . HOH R 6 . ? -0.651 -167.319 32.103 1.00 37.48 ? 610 HOH E O 1 HETATM 10426 O O . HOH R 6 . ? -0.123 -175.767 35.905 1.00 33.03 ? 611 HOH E O 1 HETATM 10427 O O . HOH R 6 . ? 16.107 -189.876 -2.789 1.00 36.02 ? 612 HOH E O 1 HETATM 10428 O O . HOH R 6 . ? -5.075 -200.718 -5.420 1.00 40.01 ? 613 HOH E O 1 HETATM 10429 O O . HOH R 6 . ? -16.444 -194.083 5.083 1.00 37.91 ? 614 HOH E O 1 HETATM 10430 O O . HOH R 6 . ? -7.993 -180.660 8.739 1.00 50.75 ? 615 HOH E O 1 HETATM 10431 O O . HOH R 6 . ? -0.497 -186.624 25.715 1.00 15.54 ? 616 HOH E O 1 HETATM 10432 O O . HOH R 6 . ? 4.981 -202.201 -1.277 1.00 40.50 ? 617 HOH E O 1 HETATM 10433 O O . HOH R 6 . ? -2.995 -207.401 26.878 1.00 21.93 ? 618 HOH E O 1 HETATM 10434 O O . HOH R 6 . ? 2.236 -175.013 19.117 1.00 21.90 ? 619 HOH E O 1 HETATM 10435 O O . HOH R 6 . ? -10.200 -191.542 25.903 1.00 34.21 ? 620 HOH E O 1 HETATM 10436 O O . HOH R 6 . ? 14.928 -203.179 29.602 1.00 18.59 ? 621 HOH E O 1 HETATM 10437 O O . HOH R 6 . ? 10.172 -174.873 31.521 1.00 20.80 ? 622 HOH E O 1 HETATM 10438 O O . HOH R 6 . ? 11.448 -211.519 28.540 1.00 21.02 ? 623 HOH E O 1 HETATM 10439 O O . HOH R 6 . ? 3.060 -170.100 13.815 1.00 25.17 ? 624 HOH E O 1 HETATM 10440 O O . HOH R 6 . ? 0.748 -177.128 18.312 1.00 19.85 ? 625 HOH E O 1 HETATM 10441 O O . HOH R 6 . ? 11.463 -184.764 35.966 1.00 25.82 ? 626 HOH E O 1 HETATM 10442 O O . HOH R 6 . ? 6.798 -178.013 31.937 1.00 15.81 ? 627 HOH E O 1 HETATM 10443 O O . HOH R 6 . ? -0.232 -203.396 28.932 1.00 14.93 ? 628 HOH E O 1 HETATM 10444 O O . HOH R 6 . ? -6.442 -200.844 24.515 1.00 36.28 ? 629 HOH E O 1 HETATM 10445 O O . HOH R 6 . ? 0.037 -180.470 24.046 1.00 18.70 ? 630 HOH E O 1 HETATM 10446 O O . HOH R 6 . ? 9.114 -188.071 32.993 1.00 23.53 ? 631 HOH E O 1 HETATM 10447 O O . HOH R 6 . ? 6.011 -179.952 21.674 1.00 12.45 ? 632 HOH E O 1 HETATM 10448 O O . HOH R 6 . ? 15.968 -202.964 21.685 1.00 26.60 ? 633 HOH E O 1 HETATM 10449 O O . HOH R 6 . ? -9.043 -201.952 25.122 1.00 30.15 ? 634 HOH E O 1 HETATM 10450 O O . HOH R 6 . ? 2.665 -205.995 10.928 1.00 21.70 ? 635 HOH E O 1 HETATM 10451 O O . HOH R 6 . ? -10.188 -195.243 26.384 1.00 31.77 ? 636 HOH E O 1 HETATM 10452 O O . HOH R 6 . ? 8.589 -215.331 36.959 1.00 27.41 ? 637 HOH E O 1 HETATM 10453 O O . HOH R 6 . ? 13.713 -185.883 12.866 1.00 30.96 ? 638 HOH E O 1 HETATM 10454 O O . HOH R 6 . ? 9.801 -197.037 2.880 1.00 28.49 ? 639 HOH E O 1 HETATM 10455 O O . HOH R 6 . ? 2.120 -170.619 21.532 1.00 37.33 ? 640 HOH E O 1 HETATM 10456 O O . HOH R 6 . ? -2.432 -179.396 16.640 1.00 27.10 ? 641 HOH E O 1 HETATM 10457 O O . HOH R 6 . ? 7.260 -190.518 20.484 1.00 15.14 ? 642 HOH E O 1 HETATM 10458 O O . HOH R 6 . ? 9.951 -195.893 13.623 1.00 20.70 ? 643 HOH E O 1 HETATM 10459 O O . HOH R 6 . ? 2.543 -208.532 5.622 1.00 35.20 ? 644 HOH E O 1 HETATM 10460 O O . HOH R 6 . ? -4.321 -196.189 27.771 1.00 22.57 ? 645 HOH E O 1 HETATM 10461 O O . HOH R 6 . ? 15.140 -178.458 28.206 1.00 21.20 ? 646 HOH E O 1 HETATM 10462 O O . HOH R 6 . ? 12.315 -169.646 25.542 1.00 26.95 ? 647 HOH E O 1 HETATM 10463 O O . HOH R 6 . ? -3.169 -218.576 42.954 1.00 33.03 ? 648 HOH E O 1 HETATM 10464 O O . HOH R 6 . ? 9.438 -186.205 35.224 1.00 38.11 ? 649 HOH E O 1 HETATM 10465 O O . HOH R 6 . ? 6.032 -200.977 17.586 1.00 17.40 ? 650 HOH E O 1 HETATM 10466 O O . HOH R 6 . ? 12.841 -187.273 18.446 1.00 29.99 ? 651 HOH E O 1 HETATM 10467 O O . HOH R 6 . ? 7.667 -199.679 32.360 1.00 26.19 ? 652 HOH E O 1 HETATM 10468 O O . HOH R 6 . ? 2.474 -175.840 15.237 1.00 22.20 ? 653 HOH E O 1 HETATM 10469 O O . HOH R 6 . ? 10.610 -169.041 23.556 1.00 33.61 ? 654 HOH E O 1 HETATM 10470 O O . HOH R 6 . ? 11.840 -229.354 33.505 1.00 51.25 ? 655 HOH E O 1 HETATM 10471 O O . HOH R 6 . ? -3.809 -187.760 22.900 1.00 23.96 ? 656 HOH E O 1 HETATM 10472 O O . HOH R 6 . ? 0.103 -178.730 9.395 1.00 35.08 ? 657 HOH E O 1 HETATM 10473 O O . HOH R 6 . ? 5.763 -178.420 0.846 1.00 38.73 ? 658 HOH E O 1 HETATM 10474 O O . HOH R 6 . ? -10.403 -198.158 11.975 1.00 38.14 ? 659 HOH E O 1 HETATM 10475 O O . HOH R 6 . ? -9.647 -207.139 30.501 1.00 28.72 ? 660 HOH E O 1 HETATM 10476 O O . HOH R 6 . ? 7.830 -197.326 34.277 1.00 33.17 ? 661 HOH E O 1 HETATM 10477 O O . HOH R 6 . ? -6.266 -181.196 22.422 1.00 41.72 ? 662 HOH E O 1 HETATM 10478 O O . HOH R 6 . ? 15.827 -191.031 31.326 1.00 43.51 ? 663 HOH E O 1 HETATM 10479 O O . HOH R 6 . ? 0.503 -206.283 20.054 1.00 27.96 ? 664 HOH E O 1 HETATM 10480 O O . HOH R 6 . ? 4.948 -206.571 12.376 1.00 25.34 ? 665 HOH E O 1 HETATM 10481 O O . HOH R 6 . ? 1.240 -182.703 8.908 1.00 20.91 ? 666 HOH E O 1 HETATM 10482 O O . HOH R 6 . ? 10.035 -212.931 36.460 1.00 31.91 ? 667 HOH E O 1 HETATM 10483 O O . HOH R 6 . ? 6.339 -205.474 10.186 1.00 28.69 ? 668 HOH E O 1 HETATM 10484 O O . HOH R 6 . ? 1.788 -168.384 15.186 1.00 43.15 ? 669 HOH E O 1 HETATM 10485 O O . HOH R 6 . ? 4.260 -187.497 32.290 1.00 28.61 ? 670 HOH E O 1 HETATM 10486 O O . HOH R 6 . ? 3.194 -175.575 1.510 1.00 37.55 ? 671 HOH E O 1 HETATM 10487 O O . HOH R 6 . ? 6.628 -198.712 22.103 1.00 21.23 ? 672 HOH E O 1 HETATM 10488 O O . HOH R 6 . ? 9.254 -193.774 33.930 1.00 39.72 ? 673 HOH E O 1 HETATM 10489 O O . HOH R 6 . ? 7.369 -169.251 30.930 1.00 27.98 ? 674 HOH E O 1 HETATM 10490 O O . HOH R 6 . ? 16.791 -176.051 27.911 1.00 37.63 ? 675 HOH E O 1 HETATM 10491 O O . HOH R 6 . ? 15.942 -190.139 16.674 1.00 22.48 ? 676 HOH E O 1 HETATM 10492 O O . HOH R 6 . ? -0.109 -175.459 22.441 1.00 35.93 ? 677 HOH E O 1 HETATM 10493 O O . HOH R 6 . ? 15.534 -188.310 30.867 1.00 36.95 ? 678 HOH E O 1 HETATM 10494 O O . HOH R 6 . ? 19.392 -193.582 7.236 1.00 33.85 ? 679 HOH E O 1 HETATM 10495 O O . HOH R 6 . ? -4.621 -195.392 35.152 1.00 38.14 ? 680 HOH E O 1 HETATM 10496 O O . HOH R 6 . ? 7.720 -192.623 9.289 1.00 31.75 ? 681 HOH E O 1 HETATM 10497 O O . HOH R 6 . ? -4.446 -180.623 5.385 1.00 39.06 ? 682 HOH E O 1 HETATM 10498 O O . HOH R 6 . ? -6.652 -188.436 16.710 1.00 30.67 ? 683 HOH E O 1 HETATM 10499 O O . HOH R 6 . ? -1.261 -177.472 20.549 1.00 31.44 ? 684 HOH E O 1 HETATM 10500 O O . HOH R 6 . ? 13.008 -203.115 13.054 1.00 24.16 ? 685 HOH E O 1 HETATM 10501 O O . HOH R 6 . ? 16.929 -203.402 19.189 1.00 30.46 ? 686 HOH E O 1 HETATM 10502 O O . HOH R 6 . ? 9.655 -190.556 34.235 1.00 31.35 ? 687 HOH E O 1 HETATM 10503 O O . HOH R 6 . ? -5.569 -200.134 0.917 1.00 43.52 ? 688 HOH E O 1 HETATM 10504 O O . HOH R 6 . ? 2.210 -167.919 27.074 1.00 32.32 ? 689 HOH E O 1 HETATM 10505 O O . HOH R 6 . ? 19.431 -197.242 19.353 1.00 27.04 ? 690 HOH E O 1 HETATM 10506 O O . HOH R 6 . ? 15.505 -182.637 5.147 1.00 37.23 ? 691 HOH E O 1 HETATM 10507 O O . HOH R 6 . ? -2.726 -188.421 25.268 1.00 28.41 ? 692 HOH E O 1 HETATM 10508 O O . HOH R 6 . ? 16.596 -199.195 29.935 1.00 37.81 ? 693 HOH E O 1 HETATM 10509 O O . HOH R 6 . ? -3.353 -178.373 29.483 1.00 39.62 ? 694 HOH E O 1 HETATM 10510 O O . HOH R 6 . ? 12.950 -196.908 30.989 1.00 29.14 ? 695 HOH E O 1 HETATM 10511 O O . HOH R 6 . ? -8.151 -229.849 33.157 1.00 47.02 ? 696 HOH E O 1 HETATM 10512 O O . HOH R 6 . ? 13.977 -206.456 33.029 1.00 44.83 ? 697 HOH E O 1 HETATM 10513 O O . HOH R 6 . ? -5.139 -192.818 34.977 1.00 43.15 ? 698 HOH E O 1 HETATM 10514 O O . HOH R 6 . ? -6.355 -182.565 10.246 1.00 36.74 ? 699 HOH E O 1 HETATM 10515 O O . HOH R 6 . ? -4.967 -181.431 12.493 1.00 34.53 ? 700 HOH E O 1 HETATM 10516 O O . HOH R 6 . ? 9.794 -218.897 29.369 1.00 39.32 ? 701 HOH E O 1 HETATM 10517 O O . HOH R 6 . ? 11.602 -216.113 28.979 1.00 42.28 ? 702 HOH E O 1 HETATM 10518 O O . HOH R 6 . ? 9.930 -210.829 26.499 1.00 26.60 ? 703 HOH E O 1 HETATM 10519 O O . HOH R 6 . ? 7.336 -199.849 19.739 1.00 28.38 ? 704 HOH E O 1 HETATM 10520 O O . HOH R 6 . ? 15.106 -205.864 29.729 1.00 42.18 ? 705 HOH E O 1 HETATM 10521 O O . HOH R 6 . ? -0.592 -185.652 28.199 1.00 19.43 ? 706 HOH E O 1 HETATM 10522 O O . HOH R 6 . ? 1.018 -173.164 20.767 1.00 26.01 ? 707 HOH E O 1 HETATM 10523 O O . HOH R 6 . ? -7.092 -178.685 27.269 1.00 53.62 ? 708 HOH E O 1 HETATM 10524 O O . HOH R 6 . ? -6.472 -185.398 19.994 1.00 37.84 ? 709 HOH E O 1 HETATM 10525 O O . HOH R 6 . ? 5.406 -168.762 11.559 1.00 43.00 ? 710 HOH E O 1 HETATM 10526 O O . HOH R 6 . ? -0.015 -166.515 13.383 1.00 52.00 ? 711 HOH E O 1 HETATM 10527 O O . HOH R 6 . ? 0.546 -168.632 19.430 1.00 44.79 ? 712 HOH E O 1 HETATM 10528 O O . HOH R 6 . ? -0.208 -177.571 23.444 1.00 31.21 ? 713 HOH E O 1 HETATM 10529 O O . HOH R 6 . ? 3.384 -176.730 8.242 1.00 29.55 ? 714 HOH E O 1 HETATM 10530 O O . HOH R 6 . ? 0.794 -175.699 7.444 1.00 31.23 ? 715 HOH E O 1 HETATM 10531 O O . HOH R 6 . ? 1.543 -174.343 2.766 1.00 36.90 ? 716 HOH E O 1 HETATM 10532 O O . HOH R 6 . ? -2.925 -205.430 8.099 1.00 26.90 ? 717 HOH E O 1 HETATM 10533 O O . HOH R 6 . ? -9.688 -203.047 8.993 1.00 37.67 ? 718 HOH E O 1 HETATM 10534 O O . HOH R 6 . ? 14.620 -200.303 4.394 1.00 39.50 ? 719 HOH E O 1 HETATM 10535 O O . HOH R 6 . ? 22.007 -196.018 8.427 1.00 41.56 ? 720 HOH E O 1 HETATM 10536 O O . HOH R 6 . ? 12.102 -182.093 35.923 1.00 29.27 ? 721 HOH E O 1 HETATM 10537 O O . HOH R 6 . ? 22.450 -187.240 34.822 1.00 49.90 ? 722 HOH E O 1 HETATM 10538 O O . HOH R 6 . ? 6.594 -187.234 33.326 1.00 31.37 ? 723 HOH E O 1 HETATM 10539 O O . HOH R 6 . ? -2.280 -199.877 37.626 1.00 27.37 ? 724 HOH E O 1 HETATM 10540 O O . HOH R 6 . ? -3.429 -197.680 37.144 1.00 34.74 ? 725 HOH E O 1 HETATM 10541 O O . HOH R 6 . ? -11.076 -203.416 35.322 1.00 27.54 ? 726 HOH E O 1 HETATM 10542 O O . HOH R 6 . ? -11.957 -206.119 37.798 1.00 36.22 ? 727 HOH E O 1 HETATM 10543 O O . HOH R 6 . ? -11.477 -205.412 31.047 1.00 34.98 ? 728 HOH E O 1 HETATM 10544 O O . HOH R 6 . ? -7.618 -190.202 22.845 1.00 41.97 ? 729 HOH E O 1 HETATM 10545 O O . HOH R 6 . ? -6.947 -210.852 18.974 1.00 51.31 ? 730 HOH E O 1 HETATM 10546 O O . HOH R 6 . ? -2.728 -211.061 26.258 1.00 32.13 ? 731 HOH E O 1 HETATM 10547 O O . HOH R 6 . ? -1.557 -208.922 25.365 1.00 22.54 ? 732 HOH E O 1 HETATM 10548 O O . HOH R 6 . ? 7.214 -210.234 13.971 1.00 40.71 ? 733 HOH E O 1 HETATM 10549 O O . HOH R 6 . ? 8.713 -231.291 31.209 1.00 50.54 ? 734 HOH E O 1 HETATM 10550 O O . HOH R 6 . ? 10.836 -220.753 40.632 1.00 50.06 ? 735 HOH E O 1 HETATM 10551 O O . HOH R 6 . ? 2.046 -233.775 34.706 1.00 33.18 ? 736 HOH E O 1 HETATM 10552 O O . HOH R 6 . ? 13.345 -202.202 32.017 1.00 39.55 ? 737 HOH E O 1 HETATM 10553 O O . HOH R 6 . ? 18.743 -200.272 31.136 1.00 39.88 ? 738 HOH E O 1 HETATM 10554 O O . HOH R 6 . ? -8.635 -216.164 39.697 1.00 42.05 ? 739 HOH E O 1 HETATM 10555 O O . HOH R 6 . ? -11.732 -213.895 33.178 1.00 39.29 ? 740 HOH E O 1 HETATM 10556 O O . HOH R 6 . ? -14.196 -201.207 15.556 1.00 41.20 ? 741 HOH E O 1 HETATM 10557 O O . HOH R 6 . ? -15.238 -203.219 16.362 1.00 46.89 ? 742 HOH E O 1 HETATM 10558 O O . HOH R 6 . ? -11.888 -198.054 13.693 1.00 39.38 ? 743 HOH E O 1 HETATM 10559 O O . HOH R 6 . ? -5.807 -236.544 40.234 1.00 44.66 ? 744 HOH E O 1 HETATM 10560 O O . HOH R 6 . ? -0.709 -239.727 36.269 1.00 43.61 ? 745 HOH E O 1 HETATM 10561 O O . HOH R 6 . ? 5.993 -234.907 35.882 1.00 47.07 ? 746 HOH E O 1 HETATM 10562 O O . HOH R 6 . ? 18.277 -184.103 36.878 1.00 39.26 ? 747 HOH E O 1 HETATM 10563 O O . HOH R 6 . ? -5.336 -173.516 24.410 1.00 50.34 ? 748 HOH E O 1 HETATM 10564 O O . HOH R 6 . ? -2.650 -181.639 14.271 1.00 32.21 ? 749 HOH E O 1 HETATM 10565 O O . HOH R 6 . ? -4.962 -178.108 9.104 1.00 46.79 ? 750 HOH E O 1 HETATM 10566 O O . HOH R 6 . ? -1.259 -177.344 8.153 1.00 33.42 ? 751 HOH E O 1 HETATM 10567 O O . HOH R 6 . ? -6.555 -232.644 42.489 1.00 47.87 ? 752 HOH E O 1 HETATM 10568 O O . HOH R 6 . ? 12.283 -216.946 26.957 1.00 36.17 ? 753 HOH E O 1 HETATM 10569 O O . HOH S 6 . ? 44.340 -143.377 58.411 1.00 48.32 ? 1301 HOH B O 1 HETATM 10570 O O . HOH S 6 . ? 41.219 -148.207 66.136 1.00 25.70 ? 1302 HOH B O 1 HETATM 10571 O O . HOH S 6 . ? 31.880 -172.082 66.053 1.00 41.97 ? 1303 HOH B O 1 HETATM 10572 O O . HOH S 6 . ? 29.347 -168.674 48.173 1.00 17.47 ? 1304 HOH B O 1 HETATM 10573 O O . HOH S 6 . ? 37.578 -169.100 50.677 1.00 29.02 ? 1305 HOH B O 1 HETATM 10574 O O . HOH S 6 . ? 32.545 -165.729 72.795 1.00 34.48 ? 1306 HOH B O 1 HETATM 10575 O O . HOH S 6 . ? 37.352 -164.304 67.714 1.00 34.16 ? 1307 HOH B O 1 HETATM 10576 O O . HOH S 6 . ? 36.956 -166.019 51.886 1.00 28.35 ? 1308 HOH B O 1 HETATM 10577 O O . HOH S 6 . ? 32.032 -163.628 75.261 1.00 50.37 ? 1309 HOH B O 1 HETATM 10578 O O . HOH S 6 . ? 35.284 -163.988 74.948 1.00 39.89 ? 1310 HOH B O 1 HETATM 10579 O O . HOH S 6 . ? 38.647 -186.767 55.856 1.00 54.24 ? 1311 HOH B O 1 HETATM 10580 O O . HOH T 6 . ? 46.716 -113.995 17.066 1.00 43.81 ? 1301 HOH D O 1 HETATM 10581 O O . HOH T 6 . ? 58.138 -101.478 36.182 1.00 29.77 ? 1302 HOH D O 1 HETATM 10582 O O . HOH T 6 . ? 57.935 -103.320 25.373 1.00 34.57 ? 1303 HOH D O 1 HETATM 10583 O O . HOH T 6 . ? 35.256 -103.075 22.810 1.00 24.19 ? 1304 HOH D O 1 HETATM 10584 O O . HOH T 6 . ? 55.527 -114.801 20.868 1.00 29.97 ? 1305 HOH D O 1 HETATM 10585 O O . HOH T 6 . ? 38.739 -107.811 25.606 1.00 28.68 ? 1306 HOH D O 1 HETATM 10586 O O . HOH T 6 . ? 37.764 -104.230 19.322 1.00 33.46 ? 1307 HOH D O 1 HETATM 10587 O O . HOH T 6 . ? 40.465 -111.265 17.646 1.00 37.01 ? 1308 HOH D O 1 HETATM 10588 O O . HOH T 6 . ? 55.294 -113.453 27.506 1.00 31.32 ? 1309 HOH D O 1 HETATM 10589 O O . HOH T 6 . ? 41.032 -107.983 23.969 1.00 36.56 ? 1310 HOH D O 1 HETATM 10590 O O . HOH T 6 . ? 37.218 -105.393 17.058 1.00 43.22 ? 1311 HOH D O 1 HETATM 10591 O O . HOH T 6 . ? 46.739 -109.281 21.510 1.00 40.27 ? 1312 HOH D O 1 HETATM 10592 O O . HOH U 6 . ? 3.999 -183.642 -1.991 1.00 27.01 ? 1301 HOH F O 1 HETATM 10593 O O . HOH U 6 . ? 18.695 -190.003 18.665 1.00 18.14 ? 1302 HOH F O 1 HETATM 10594 O O . HOH U 6 . ? 12.930 -191.528 25.087 1.00 16.44 ? 1303 HOH F O 1 HETATM 10595 O O . HOH U 6 . ? 4.069 -174.838 10.190 1.00 32.06 ? 1304 HOH F O 1 HETATM 10596 O O . HOH U 6 . ? 7.863 -170.032 13.088 1.00 29.45 ? 1305 HOH F O 1 HETATM 10597 O O . HOH U 6 . ? 13.309 -184.858 17.525 1.00 33.83 ? 1306 HOH F O 1 HETATM 10598 O O . HOH U 6 . ? 5.652 -176.431 3.265 1.00 42.26 ? 1307 HOH F O 1 HETATM 10599 O O . HOH U 6 . ? 23.163 -192.439 18.494 1.00 38.03 ? 1308 HOH F O 1 HETATM 10600 O O . HOH U 6 . ? 8.343 -169.091 9.528 1.00 42.15 ? 1309 HOH F O 1 HETATM 10601 O O . HOH U 6 . ? 13.308 -175.219 12.422 1.00 46.81 ? 1310 HOH F O 1 HETATM 10602 O O . HOH U 6 . ? 9.356 -192.553 1.445 1.00 39.96 ? 1311 HOH F O 1 HETATM 10603 O O . HOH U 6 . ? 20.081 -185.930 18.630 1.00 32.44 ? 1312 HOH F O 1 HETATM 10604 O O . HOH U 6 . ? 11.821 -175.816 10.348 1.00 40.52 ? 1313 HOH F O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLY 1 59 ? ? ? A . n A 1 2 SER 2 60 ? ? ? A . n A 1 3 ALA 3 61 ? ? ? A . n A 1 4 MET 4 62 ? ? ? A . n A 1 5 GLY 5 63 ? ? ? A . n A 1 6 SER 6 64 ? ? ? A . n A 1 7 ALA 7 65 ? ? ? A . n A 1 8 SER 8 66 ? ? ? A . n A 1 9 THR 9 67 ? ? ? A . n A 1 10 SER 10 68 68 SER SER A . n A 1 11 GLY 11 69 69 GLY GLY A . n A 1 12 ASN 12 70 70 ASN ASN A . n A 1 13 PRO 13 71 71 PRO PRO A . n A 1 14 PHE 14 72 72 PHE PHE A . n A 1 15 GLN 15 73 73 GLN GLN A . n A 1 16 ALA 16 74 74 ALA ALA A . n A 1 17 ASN 17 75 75 ASN ASN A . n A 1 18 VAL 18 76 76 VAL VAL A . n A 1 19 GLU 19 77 77 GLU GLU A . n A 1 20 MET 20 78 78 MET MET A . n A 1 21 LYS 21 79 79 LYS LYS A . n A 1 22 THR 22 80 80 THR THR A . n A 1 23 PHE 23 81 81 PHE PHE A . n A 1 24 MET 24 82 82 MET MET A . n A 1 25 GLU 25 83 83 GLU GLU A . n A 1 26 ARG 26 84 84 ARG ARG A . n A 1 27 PHE 27 85 85 PHE PHE A . n A 1 28 ASN 28 86 86 ASN ASN A . n A 1 29 LEU 29 87 87 LEU LEU A . n A 1 30 THR 30 88 88 THR THR A . n A 1 31 HIS 31 89 89 HIS HIS A . n A 1 32 HIS 32 90 90 HIS HIS A . n A 1 33 HIS 33 91 91 HIS HIS A . n A 1 34 GLN 34 92 92 GLN GLN A . n A 1 35 SER 35 93 93 SER SER A . n A 1 36 GLY 36 94 94 GLY GLY A . n A 1 37 ILE 37 95 95 ILE ILE A . n A 1 38 TYR 38 96 96 TYR TYR A . n A 1 39 VAL 39 97 97 VAL VAL A . n A 1 40 ASP 40 98 98 ASP ASP A . n A 1 41 LEU 41 99 99 LEU LEU A . n A 1 42 GLY 42 100 100 GLY GLY A . n A 1 43 GLN 43 101 101 GLN GLN A . n A 1 44 ASP 44 102 102 ASP ASP A . n A 1 45 LYS 45 103 103 LYS LYS A . n A 1 46 GLU 46 104 104 GLU GLU A . n A 1 47 VAL 47 105 105 VAL VAL A . n A 1 48 ASP 48 106 106 ASP ASP A . n A 1 49 GLY 49 107 107 GLY GLY A . n A 1 50 THR 50 108 108 THR THR A . n A 1 51 LEU 51 109 109 LEU LEU A . n A 1 52 TYR 52 110 110 TYR TYR A . n A 1 53 ARG 53 111 111 ARG ARG A . n A 1 54 GLU 54 112 112 GLU GLU A . n A 1 55 PRO 55 113 113 PRO PRO A . n A 1 56 ALA 56 114 114 ALA ALA A . n A 1 57 GLY 57 115 115 GLY GLY A . n A 1 58 LEU 58 116 116 LEU LEU A . n A 1 59 CYS 59 117 117 CYS CYS A . n A 1 60 PRO 60 118 118 PRO PRO A . n A 1 61 ILE 61 119 119 ILE ILE A . n A 1 62 TRP 62 120 120 TRP TRP A . n A 1 63 GLY 63 121 121 GLY GLY A . n A 1 64 LYS 64 122 122 LYS LYS A . n A 1 65 HIS 65 123 123 HIS HIS A . n A 1 66 ILE 66 124 124 ILE ILE A . n A 1 67 GLU 67 125 125 GLU GLU A . n A 1 68 LEU 68 126 126 LEU LEU A . n A 1 69 GLN 69 127 127 GLN GLN A . n A 1 70 GLN 70 128 128 GLN GLN A . n A 1 71 PRO 71 129 129 PRO PRO A . n A 1 72 ASP 72 130 130 ASP ASP A . n A 1 73 ARG 73 131 131 ARG ARG A . n A 1 74 PRO 74 132 132 PRO PRO A . n A 1 75 PRO 75 133 133 PRO PRO A . n A 1 76 TYR 76 134 134 TYR TYR A . n A 1 77 ARG 77 135 135 ARG ARG A . n A 1 78 ASN 78 136 136 ASN ASN A . n A 1 79 ASN 79 137 137 ASN ASN A . n A 1 80 PHE 80 138 138 PHE PHE A . n A 1 81 LEU 81 139 139 LEU LEU A . n A 1 82 GLU 82 140 140 GLU GLU A . n A 1 83 ASP 83 141 141 ASP ASP A . n A 1 84 VAL 84 142 142 VAL VAL A . n A 1 85 PRO 85 143 143 PRO PRO A . n A 1 86 THR 86 144 144 THR THR A . n A 1 87 GLU 87 145 145 GLU GLU A . n A 1 88 LYS 88 146 146 LYS LYS A . n A 1 89 GLU 89 147 147 GLU GLU A . n A 1 90 TYR 90 148 148 TYR TYR A . n A 1 91 LYS 91 149 149 LYS LYS A . n A 1 92 GLN 92 150 150 GLN GLN A . n A 1 93 SER 93 151 151 SER SER A . n A 1 94 GLY 94 152 152 GLY GLY A . n A 1 95 ASN 95 153 153 ASN ASN A . n A 1 96 PRO 96 154 154 PRO PRO A . n A 1 97 LEU 97 155 155 LEU LEU A . n A 1 98 PRO 98 156 156 PRO PRO A . n A 1 99 GLY 99 157 157 GLY GLY A . n A 1 100 GLY 100 158 158 GLY GLY A . n A 1 101 PHE 101 159 159 PHE PHE A . n A 1 102 ASN 102 160 160 ASN ASN A . n A 1 103 LEU 103 161 161 LEU LEU A . n A 1 104 ASN 104 162 162 ASN ASN A . n A 1 105 PHE 105 163 163 PHE PHE A . n A 1 106 VAL 106 164 164 VAL VAL A . n A 1 107 THR 107 165 165 THR THR A . n A 1 108 PRO 108 166 166 PRO PRO A . n A 1 109 SER 109 167 167 SER SER A . n A 1 110 GLY 110 168 168 GLY GLY A . n A 1 111 GLN 111 169 169 GLN GLN A . n A 1 112 ARG 112 170 170 ARG ARG A . n A 1 113 ILE 113 171 171 ILE ILE A . n A 1 114 SER 114 172 172 SER SER A . n A 1 115 PRO 115 173 173 PRO PRO A . n A 1 116 PHE 116 174 174 PHE PHE A . n A 1 117 PRO 117 175 175 PRO PRO A . n A 1 118 MET 118 176 176 MET MET A . n A 1 119 GLU 119 177 177 GLU GLU A . n A 1 120 LEU 120 178 178 LEU LEU A . n A 1 121 LEU 121 179 179 LEU LEU A . n A 1 122 GLU 122 180 180 GLU GLU A . n A 1 123 LYS 123 181 181 LYS LYS A . n A 1 124 ASN 124 182 182 ASN ASN A . n A 1 125 SER 125 183 183 SER SER A . n A 1 126 ASN 126 184 184 ASN ASN A . n A 1 127 ILE 127 185 185 ILE ILE A . n A 1 128 LYS 128 186 186 LYS LYS A . n A 1 129 ALA 129 187 187 ALA ALA A . n A 1 130 SER 130 188 188 SER SER A . n A 1 131 THR 131 189 189 THR THR A . n A 1 132 ASP 132 190 190 ASP ASP A . n A 1 133 LEU 133 191 191 LEU LEU A . n A 1 134 GLY 134 192 192 GLY GLY A . n A 1 135 ARG 135 193 193 ARG ARG A . n A 1 136 CYS 136 194 194 CYS CYS A . n A 1 137 ALA 137 195 195 ALA ALA A . n A 1 138 GLU 138 196 196 GLU GLU A . n A 1 139 PHE 139 197 197 PHE PHE A . n A 1 140 ALA 140 198 198 ALA ALA A . n A 1 141 PHE 141 199 199 PHE PHE A . n A 1 142 LYS 142 200 200 LYS LYS A . n A 1 143 THR 143 201 201 THR THR A . n A 1 144 VAL 144 202 202 VAL VAL A . n A 1 145 ALA 145 203 203 ALA ALA A . n A 1 146 MET 146 204 204 MET MET A . n A 1 147 ASP 147 205 205 ASP ASP A . n A 1 148 LYS 148 206 206 LYS LYS A . n A 1 149 ASN 149 207 207 ASN ASN A . n A 1 150 ASN 150 208 208 ASN ASN A . n A 1 151 LYS 151 209 209 LYS LYS A . n A 1 152 ALA 152 210 210 ALA ALA A . n A 1 153 THR 153 211 211 THR THR A . n A 1 154 LYS 154 212 212 LYS LYS A . n A 1 155 TYR 155 213 213 TYR TYR A . n A 1 156 ARG 156 214 214 ARG ARG A . n A 1 157 TYR 157 215 215 TYR TYR A . n A 1 158 PRO 158 216 216 PRO PRO A . n A 1 159 PHE 159 217 217 PHE PHE A . n A 1 160 VAL 160 218 218 VAL VAL A . n A 1 161 TYR 161 219 219 TYR TYR A . n A 1 162 ASP 162 220 220 ASP ASP A . n A 1 163 SER 163 221 221 SER SER A . n A 1 164 LYS 164 222 222 LYS LYS A . n A 1 165 LYS 165 223 223 LYS LYS A . n A 1 166 ARG 166 224 224 ARG ARG A . n A 1 167 LEU 167 225 225 LEU LEU A . n A 1 168 CYS 168 226 226 CYS CYS A . n A 1 169 HIS 169 227 227 HIS HIS A . n A 1 170 ILE 170 228 228 ILE ILE A . n A 1 171 LEU 171 229 229 LEU LEU A . n A 1 172 TYR 172 230 230 TYR TYR A . n A 1 173 VAL 173 231 231 VAL VAL A . n A 1 174 SER 174 232 232 SER SER A . n A 1 175 MET 175 233 233 MET MET A . n A 1 176 GLN 176 234 234 GLN GLN A . n A 1 177 LEU 177 235 235 LEU LEU A . n A 1 178 MET 178 236 236 MET MET A . n A 1 179 GLU 179 237 237 GLU GLU A . n A 1 180 GLY 180 238 238 GLY GLY A . n A 1 181 LYS 181 239 239 LYS LYS A . n A 1 182 LYS 182 240 240 LYS LYS A . n A 1 183 TYR 183 241 241 TYR TYR A . n A 1 184 CYS 184 242 242 CYS CYS A . n A 1 185 SER 185 243 243 SER SER A . n A 1 186 VAL 186 244 244 VAL VAL A . n A 1 187 LYS 187 245 245 LYS LYS A . n A 1 188 GLY 188 246 246 GLY GLY A . n A 1 189 GLU 189 247 247 GLU GLU A . n A 1 190 PRO 190 248 248 PRO PRO A . n A 1 191 PRO 191 249 249 PRO PRO A . n A 1 192 ASP 192 250 250 ASP ASP A . n A 1 193 LEU 193 251 251 LEU LEU A . n A 1 194 THR 194 252 252 THR THR A . n A 1 195 TRP 195 253 253 TRP TRP A . n A 1 196 TYR 196 254 254 TYR TYR A . n A 1 197 CYS 197 255 255 CYS CYS A . n A 1 198 PHE 198 256 256 PHE PHE A . n A 1 199 LYS 199 257 257 LYS LYS A . n A 1 200 PRO 200 258 258 PRO PRO A . n A 1 201 ARG 201 259 259 ARG ARG A . n A 1 202 LYS 202 260 260 LYS LYS A . n A 1 203 SER 203 261 261 SER SER A . n A 1 204 VAL 204 262 262 VAL VAL A . n A 1 205 THR 205 263 263 THR THR A . n A 1 206 GLU 206 264 264 GLU GLU A . n A 1 207 ASN 207 265 265 ASN ASN A . n A 1 208 HIS 208 266 266 HIS HIS A . n A 1 209 HIS 209 267 267 HIS HIS A . n A 1 210 LEU 210 268 268 LEU LEU A . n A 1 211 ILE 211 269 269 ILE ILE A . n A 1 212 TYR 212 270 270 TYR TYR A . n A 1 213 GLY 213 271 271 GLY GLY A . n A 1 214 SER 214 272 272 SER SER A . n A 1 215 ALA 215 273 273 ALA ALA A . n A 1 216 TYR 216 274 274 TYR TYR A . n A 1 217 VAL 217 275 275 VAL VAL A . n A 1 218 GLY 218 276 276 GLY GLY A . n A 1 219 GLU 219 277 277 GLU GLU A . n A 1 220 ASN 220 278 278 ASN ASN A . n A 1 221 PRO 221 279 279 PRO PRO A . n A 1 222 ASP 222 280 280 ASP ASP A . n A 1 223 ALA 223 281 281 ALA ALA A . n A 1 224 PHE 224 282 282 PHE PHE A . n A 1 225 ILE 225 283 283 ILE ILE A . n A 1 226 SER 226 284 284 SER SER A . n A 1 227 LYS 227 285 285 LYS LYS A . n A 1 228 CYS 228 286 286 CYS CYS A . n A 1 229 PRO 229 287 287 PRO PRO A . n A 1 230 ASN 230 288 288 ASN ASN A . n A 1 231 GLN 231 289 289 GLN GLN A . n A 1 232 ALA 232 290 290 ALA ALA A . n A 1 233 LEU 233 291 291 LEU LEU A . n A 1 234 ARG 234 292 292 ARG ARG A . n A 1 235 GLY 235 293 293 GLY GLY A . n A 1 236 TYR 236 294 294 TYR TYR A . n A 1 237 ARG 237 295 295 ARG ARG A . n A 1 238 PHE 238 296 296 PHE PHE A . n A 1 239 GLY 239 297 297 GLY GLY A . n A 1 240 VAL 240 298 298 VAL VAL A . n A 1 241 TRP 241 299 299 TRP TRP A . n A 1 242 LYS 242 300 300 LYS LYS A . n A 1 243 LYS 243 301 301 LYS LYS A . n A 1 244 GLY 244 302 302 GLY GLY A . n A 1 245 ARG 245 303 303 ARG ARG A . n A 1 246 CYS 246 304 304 CYS CYS A . n A 1 247 LEU 247 305 305 LEU LEU A . n A 1 248 ASP 248 306 306 ASP ASP A . n A 1 249 TYR 249 307 307 TYR TYR A . n A 1 250 THR 250 308 308 THR THR A . n A 1 251 GLU 251 309 309 GLU GLU A . n A 1 252 LEU 252 310 310 LEU LEU A . n A 1 253 THR 253 311 311 THR THR A . n A 1 254 ASP 254 312 312 ASP ASP A . n A 1 255 THR 255 313 313 THR THR A . n A 1 256 VAL 256 314 314 VAL VAL A . n A 1 257 ILE 257 315 315 ILE ILE A . n A 1 258 GLU 258 316 316 GLU GLU A . n A 1 259 ARG 259 317 317 ARG ARG A . n A 1 260 VAL 260 318 318 VAL VAL A . n A 1 261 GLU 261 319 319 GLU GLU A . n A 1 262 SER 262 320 320 SER SER A . n A 1 263 LYS 263 321 321 LYS LYS A . n A 1 264 ALA 264 322 322 ALA ALA A . n A 1 265 GLN 265 323 323 GLN GLN A . n A 1 266 CYS 266 324 324 CYS CYS A . n A 1 267 TRP 267 325 325 TRP TRP A . n A 1 268 VAL 268 326 326 VAL VAL A . n A 1 269 LYS 269 327 327 LYS LYS A . n A 1 270 THR 270 328 328 THR THR A . n A 1 271 PHE 271 329 329 PHE PHE A . n A 1 272 GLU 272 330 330 GLU GLU A . n A 1 273 ASN 273 331 331 ASN ASN A . n A 1 274 ASP 274 332 332 ASP ASP A . n A 1 275 GLY 275 333 333 GLY GLY A . n A 1 276 VAL 276 334 334 VAL VAL A . n A 1 277 ALA 277 335 335 ALA ALA A . n A 1 278 SER 278 336 336 SER SER A . n A 1 279 ASP 279 337 337 ASP ASP A . n A 1 280 GLN 280 338 338 GLN GLN A . n A 1 281 PRO 281 339 339 PRO PRO A . n A 1 282 GLY 282 353 ? ? ? A . n A 1 283 SER 283 354 ? ? ? A . n A 1 284 GLY 284 355 ? ? ? A . n A 1 285 SER 285 356 ? ? ? A . n A 1 286 GLY 286 357 ? ? ? A . n A 1 287 SER 287 358 ? ? ? A . n A 1 288 GLY 288 359 ? ? ? A . n A 1 289 ASP 289 360 360 ASP ASP A . n A 1 290 GLN 290 361 361 GLN GLN A . n A 1 291 PRO 291 362 362 PRO PRO A . n A 1 292 HIS 292 363 363 HIS HIS A . n A 1 293 SER 293 364 364 SER SER A . n A 1 294 GLY 294 365 365 GLY GLY A . n A 1 295 GLY 295 366 366 GLY GLY A . n A 1 296 VAL 296 367 367 VAL VAL A . n A 1 297 GLY 297 368 368 GLY GLY A . n A 1 298 ARG 298 369 369 ARG ARG A . n A 1 299 ASN 299 370 370 ASN ASN A . n A 1 300 TYR 300 371 371 TYR TYR A . n A 1 301 GLY 301 372 372 GLY GLY A . n A 1 302 PHE 302 373 373 PHE PHE A . n A 1 303 TYR 303 374 374 TYR TYR A . n A 1 304 TYR 304 375 375 TYR TYR A . n A 1 305 VAL 305 376 376 VAL VAL A . n A 1 306 ASP 306 377 377 ASP ASP A . n A 1 307 THR 307 378 378 THR THR A . n A 1 308 THR 308 379 379 THR THR A . n A 1 309 GLY 309 380 380 GLY GLY A . n A 1 310 GLU 310 381 381 GLU GLU A . n A 1 311 GLY 311 382 382 GLY GLY A . n A 1 312 LYS 312 383 383 LYS LYS A . n A 1 313 CYS 313 384 384 CYS CYS A . n A 1 314 ALA 314 385 385 ALA ALA A . n A 1 315 LEU 315 386 386 LEU LEU A . n A 1 316 SER 316 387 387 SER SER A . n A 1 317 ASP 317 388 388 ASP ASP A . n A 1 318 GLN 318 389 389 GLN GLN A . n A 1 319 VAL 319 390 390 VAL VAL A . n A 1 320 PRO 320 391 391 PRO PRO A . n A 1 321 ASP 321 392 392 ASP ASP A . n A 1 322 CYS 322 393 393 CYS CYS A . n A 1 323 LEU 323 394 394 LEU LEU A . n A 1 324 VAL 324 395 395 VAL VAL A . n A 1 325 SER 325 396 396 SER SER A . n A 1 326 ASP 326 397 397 ASP ASP A . n A 1 327 SER 327 398 398 SER SER A . n A 1 328 ALA 328 399 399 ALA ALA A . n A 1 329 ALA 329 400 400 ALA ALA A . n A 1 330 VAL 330 401 401 VAL VAL A . n A 1 331 SER 331 402 402 SER SER A . n A 1 332 TYR 332 403 403 TYR TYR A . n A 1 333 THR 333 404 404 THR THR A . n A 1 334 ALA 334 405 405 ALA ALA A . n A 1 335 ALA 335 406 406 ALA ALA A . n A 1 336 GLY 336 407 407 GLY GLY A . n A 1 337 SER 337 408 408 SER SER A . n A 1 338 LEU 338 409 409 LEU LEU A . n A 1 339 SER 339 410 410 SER SER A . n A 1 340 GLU 340 411 411 GLU GLU A . n A 1 341 GLU 341 412 412 GLU GLU A . n A 1 342 THR 342 413 413 THR THR A . n A 1 343 PRO 343 414 414 PRO PRO A . n A 1 344 ASN 344 415 415 ASN ASN A . n A 1 345 PHE 345 416 416 PHE PHE A . n A 1 346 ILE 346 417 417 ILE ILE A . n A 1 347 ILE 347 418 418 ILE ILE A . n A 1 348 PRO 348 419 419 PRO PRO A . n A 1 349 SER 349 420 420 SER SER A . n A 1 350 ASN 350 421 421 ASN ASN A . n A 1 351 PRO 351 422 422 PRO PRO A . n A 1 352 SER 352 423 423 SER SER A . n A 1 353 VAL 353 424 424 VAL VAL A . n A 1 354 THR 354 425 425 THR THR A . n A 1 355 PRO 355 426 426 PRO PRO A . n A 1 356 PRO 356 427 427 PRO PRO A . n A 1 357 THR 357 428 428 THR THR A . n A 1 358 PRO 358 429 429 PRO PRO A . n A 1 359 GLU 359 430 430 GLU GLU A . n A 1 360 THR 360 431 431 THR THR A . n A 1 361 ALA 361 432 432 ALA ALA A . n A 1 362 LEU 362 433 433 LEU LEU A . n A 1 363 GLN 363 434 434 GLN GLN A . n A 1 364 CYS 364 435 435 CYS CYS A . n A 1 365 THR 365 436 436 THR THR A . n A 1 366 ALA 366 437 437 ALA ALA A . n A 1 367 ASP 367 438 438 ASP ASP A . n A 1 368 LYS 368 439 439 LYS LYS A . n A 1 369 PHE 369 440 440 PHE PHE A . n A 1 370 PRO 370 441 441 PRO PRO A . n A 1 371 ASP 371 442 442 ASP ASP A . n A 1 372 SER 372 443 443 SER SER A . n A 1 373 PHE 373 444 444 PHE PHE A . n A 1 374 GLY 374 445 445 GLY GLY A . n A 1 375 ALA 375 446 446 ALA ALA A . n A 1 376 CYS 376 447 447 CYS CYS A . n A 1 377 ASP 377 448 448 ASP ASP A . n A 1 378 VAL 378 449 449 VAL VAL A . n A 1 379 GLN 379 450 450 GLN GLN A . n A 1 380 ALA 380 451 451 ALA ALA A . n A 1 381 CYS 381 452 452 CYS CYS A . n A 1 382 LYS 382 453 453 LYS LYS A . n A 1 383 ARG 383 454 454 ARG ARG A . n A 1 384 GLN 384 455 455 GLN GLN A . n A 1 385 LYS 385 456 456 LYS LYS A . n A 1 386 THR 386 457 457 THR THR A . n A 1 387 SER 387 458 458 SER SER A . n A 1 388 CYS 388 459 459 CYS CYS A . n A 1 389 VAL 389 460 460 VAL VAL A . n A 1 390 GLY 390 461 461 GLY GLY A . n A 1 391 GLY 391 462 462 GLY GLY A . n A 1 392 GLN 392 463 463 GLN GLN A . n A 1 393 ILE 393 464 464 ILE ILE A . n A 1 394 GLN 394 465 465 GLN GLN A . n A 1 395 SER 395 466 466 SER SER A . n A 1 396 THR 396 467 467 THR THR A . n A 1 397 SER 397 468 468 SER SER A . n A 1 398 VAL 398 469 469 VAL VAL A . n A 1 399 ASP 399 470 470 ASP ASP A . n A 1 400 CYS 400 471 471 CYS CYS A . n A 1 401 THR 401 472 472 THR THR A . n A 1 402 ALA 402 473 473 ALA ALA A . n A 1 403 ASP 403 474 474 ASP ASP A . n A 1 404 GLU 404 475 475 GLU GLU A . n A 1 405 GLN 405 476 476 GLN GLN A . n A 1 406 ASN 406 477 477 ASN ASN A . n A 1 407 GLU 407 478 478 GLU GLU A . n A 1 408 CYS 408 479 479 CYS CYS A . n A 1 409 GLY 409 480 ? ? ? A . n A 1 410 SER 410 481 ? ? ? A . n A 1 411 ASN 411 482 ? ? ? A . n A 1 412 THR 412 483 ? ? ? A . n A 1 413 ALA 413 484 ? ? ? A . n A 1 414 ALA 414 485 ? ? ? A . n A 1 415 ALA 415 486 ? ? ? A . n A 1 416 LEU 416 487 ? ? ? A . n A 1 417 VAL 417 488 ? ? ? A . n A 1 418 PRO 418 489 ? ? ? A . n A 1 419 ARG 419 490 ? ? ? A . n B 1 1 GLY 1 59 ? ? ? C . n B 1 2 SER 2 60 ? ? ? C . n B 1 3 ALA 3 61 ? ? ? C . n B 1 4 MET 4 62 ? ? ? C . n B 1 5 GLY 5 63 ? ? ? C . n B 1 6 SER 6 64 ? ? ? C . n B 1 7 ALA 7 65 ? ? ? C . n B 1 8 SER 8 66 ? ? ? C . n B 1 9 THR 9 67 ? ? ? C . n B 1 10 SER 10 68 68 SER SER C . n B 1 11 GLY 11 69 69 GLY GLY C . n B 1 12 ASN 12 70 70 ASN ASN C . n B 1 13 PRO 13 71 71 PRO PRO C . n B 1 14 PHE 14 72 72 PHE PHE C . n B 1 15 GLN 15 73 73 GLN GLN C . n B 1 16 ALA 16 74 74 ALA ALA C . n B 1 17 ASN 17 75 75 ASN ASN C . n B 1 18 VAL 18 76 76 VAL VAL C . n B 1 19 GLU 19 77 77 GLU GLU C . n B 1 20 MET 20 78 78 MET MET C . n B 1 21 LYS 21 79 79 LYS LYS C . n B 1 22 THR 22 80 80 THR THR C . n B 1 23 PHE 23 81 81 PHE PHE C . n B 1 24 MET 24 82 82 MET MET C . n B 1 25 GLU 25 83 83 GLU GLU C . n B 1 26 ARG 26 84 84 ARG ARG C . n B 1 27 PHE 27 85 85 PHE PHE C . n B 1 28 ASN 28 86 86 ASN ASN C . n B 1 29 LEU 29 87 87 LEU LEU C . n B 1 30 THR 30 88 88 THR THR C . n B 1 31 HIS 31 89 89 HIS HIS C . n B 1 32 HIS 32 90 90 HIS HIS C . n B 1 33 HIS 33 91 91 HIS HIS C . n B 1 34 GLN 34 92 92 GLN GLN C . n B 1 35 SER 35 93 93 SER SER C . n B 1 36 GLY 36 94 94 GLY GLY C . n B 1 37 ILE 37 95 95 ILE ILE C . n B 1 38 TYR 38 96 96 TYR TYR C . n B 1 39 VAL 39 97 97 VAL VAL C . n B 1 40 ASP 40 98 98 ASP ASP C . n B 1 41 LEU 41 99 99 LEU LEU C . n B 1 42 GLY 42 100 100 GLY GLY C . n B 1 43 GLN 43 101 101 GLN GLN C . n B 1 44 ASP 44 102 102 ASP ASP C . n B 1 45 LYS 45 103 103 LYS LYS C . n B 1 46 GLU 46 104 104 GLU GLU C . n B 1 47 VAL 47 105 105 VAL VAL C . n B 1 48 ASP 48 106 106 ASP ASP C . n B 1 49 GLY 49 107 107 GLY GLY C . n B 1 50 THR 50 108 108 THR THR C . n B 1 51 LEU 51 109 109 LEU LEU C . n B 1 52 TYR 52 110 110 TYR TYR C . n B 1 53 ARG 53 111 111 ARG ARG C . n B 1 54 GLU 54 112 112 GLU GLU C . n B 1 55 PRO 55 113 113 PRO PRO C . n B 1 56 ALA 56 114 114 ALA ALA C . n B 1 57 GLY 57 115 115 GLY GLY C . n B 1 58 LEU 58 116 116 LEU LEU C . n B 1 59 CYS 59 117 117 CYS CYS C . n B 1 60 PRO 60 118 118 PRO PRO C . n B 1 61 ILE 61 119 119 ILE ILE C . n B 1 62 TRP 62 120 120 TRP TRP C . n B 1 63 GLY 63 121 121 GLY GLY C . n B 1 64 LYS 64 122 122 LYS LYS C . n B 1 65 HIS 65 123 123 HIS HIS C . n B 1 66 ILE 66 124 124 ILE ILE C . n B 1 67 GLU 67 125 125 GLU GLU C . n B 1 68 LEU 68 126 126 LEU LEU C . n B 1 69 GLN 69 127 127 GLN GLN C . n B 1 70 GLN 70 128 128 GLN GLN C . n B 1 71 PRO 71 129 129 PRO PRO C . n B 1 72 ASP 72 130 130 ASP ASP C . n B 1 73 ARG 73 131 131 ARG ARG C . n B 1 74 PRO 74 132 132 PRO PRO C . n B 1 75 PRO 75 133 133 PRO PRO C . n B 1 76 TYR 76 134 134 TYR TYR C . n B 1 77 ARG 77 135 135 ARG ARG C . n B 1 78 ASN 78 136 136 ASN ASN C . n B 1 79 ASN 79 137 137 ASN ASN C . n B 1 80 PHE 80 138 138 PHE PHE C . n B 1 81 LEU 81 139 139 LEU LEU C . n B 1 82 GLU 82 140 140 GLU GLU C . n B 1 83 ASP 83 141 141 ASP ASP C . n B 1 84 VAL 84 142 142 VAL VAL C . n B 1 85 PRO 85 143 143 PRO PRO C . n B 1 86 THR 86 144 144 THR THR C . n B 1 87 GLU 87 145 145 GLU GLU C . n B 1 88 LYS 88 146 146 LYS LYS C . n B 1 89 GLU 89 147 147 GLU GLU C . n B 1 90 TYR 90 148 148 TYR TYR C . n B 1 91 LYS 91 149 149 LYS LYS C . n B 1 92 GLN 92 150 150 GLN GLN C . n B 1 93 SER 93 151 151 SER SER C . n B 1 94 GLY 94 152 152 GLY GLY C . n B 1 95 ASN 95 153 153 ASN ASN C . n B 1 96 PRO 96 154 154 PRO PRO C . n B 1 97 LEU 97 155 155 LEU LEU C . n B 1 98 PRO 98 156 156 PRO PRO C . n B 1 99 GLY 99 157 157 GLY GLY C . n B 1 100 GLY 100 158 158 GLY GLY C . n B 1 101 PHE 101 159 159 PHE PHE C . n B 1 102 ASN 102 160 160 ASN ASN C . n B 1 103 LEU 103 161 161 LEU LEU C . n B 1 104 ASN 104 162 162 ASN ASN C . n B 1 105 PHE 105 163 163 PHE PHE C . n B 1 106 VAL 106 164 164 VAL VAL C . n B 1 107 THR 107 165 165 THR THR C . n B 1 108 PRO 108 166 166 PRO PRO C . n B 1 109 SER 109 167 167 SER SER C . n B 1 110 GLY 110 168 168 GLY GLY C . n B 1 111 GLN 111 169 169 GLN GLN C . n B 1 112 ARG 112 170 170 ARG ARG C . n B 1 113 ILE 113 171 171 ILE ILE C . n B 1 114 SER 114 172 172 SER SER C . n B 1 115 PRO 115 173 173 PRO PRO C . n B 1 116 PHE 116 174 174 PHE PHE C . n B 1 117 PRO 117 175 175 PRO PRO C . n B 1 118 MET 118 176 176 MET MET C . n B 1 119 GLU 119 177 177 GLU GLU C . n B 1 120 LEU 120 178 178 LEU LEU C . n B 1 121 LEU 121 179 179 LEU LEU C . n B 1 122 GLU 122 180 180 GLU GLU C . n B 1 123 LYS 123 181 181 LYS LYS C . n B 1 124 ASN 124 182 182 ASN ASN C . n B 1 125 SER 125 183 183 SER SER C . n B 1 126 ASN 126 184 184 ASN ASN C . n B 1 127 ILE 127 185 185 ILE ILE C . n B 1 128 LYS 128 186 186 LYS LYS C . n B 1 129 ALA 129 187 187 ALA ALA C . n B 1 130 SER 130 188 188 SER SER C . n B 1 131 THR 131 189 189 THR THR C . n B 1 132 ASP 132 190 190 ASP ASP C . n B 1 133 LEU 133 191 191 LEU LEU C . n B 1 134 GLY 134 192 192 GLY GLY C . n B 1 135 ARG 135 193 193 ARG ARG C . n B 1 136 CYS 136 194 194 CYS CYS C . n B 1 137 ALA 137 195 195 ALA ALA C . n B 1 138 GLU 138 196 196 GLU GLU C . n B 1 139 PHE 139 197 197 PHE PHE C . n B 1 140 ALA 140 198 198 ALA ALA C . n B 1 141 PHE 141 199 199 PHE PHE C . n B 1 142 LYS 142 200 200 LYS LYS C . n B 1 143 THR 143 201 201 THR THR C . n B 1 144 VAL 144 202 202 VAL VAL C . n B 1 145 ALA 145 203 203 ALA ALA C . n B 1 146 MET 146 204 204 MET MET C . n B 1 147 ASP 147 205 205 ASP ASP C . n B 1 148 LYS 148 206 206 LYS LYS C . n B 1 149 ASN 149 207 207 ASN ASN C . n B 1 150 ASN 150 208 208 ASN ASN C . n B 1 151 LYS 151 209 209 LYS LYS C . n B 1 152 ALA 152 210 210 ALA ALA C . n B 1 153 THR 153 211 211 THR THR C . n B 1 154 LYS 154 212 212 LYS LYS C . n B 1 155 TYR 155 213 213 TYR TYR C . n B 1 156 ARG 156 214 214 ARG ARG C . n B 1 157 TYR 157 215 215 TYR TYR C . n B 1 158 PRO 158 216 216 PRO PRO C . n B 1 159 PHE 159 217 217 PHE PHE C . n B 1 160 VAL 160 218 218 VAL VAL C . n B 1 161 TYR 161 219 219 TYR TYR C . n B 1 162 ASP 162 220 220 ASP ASP C . n B 1 163 SER 163 221 221 SER SER C . n B 1 164 LYS 164 222 222 LYS LYS C . n B 1 165 LYS 165 223 223 LYS LYS C . n B 1 166 ARG 166 224 224 ARG ARG C . n B 1 167 LEU 167 225 225 LEU LEU C . n B 1 168 CYS 168 226 226 CYS CYS C . n B 1 169 HIS 169 227 227 HIS HIS C . n B 1 170 ILE 170 228 228 ILE ILE C . n B 1 171 LEU 171 229 229 LEU LEU C . n B 1 172 TYR 172 230 230 TYR TYR C . n B 1 173 VAL 173 231 231 VAL VAL C . n B 1 174 SER 174 232 232 SER SER C . n B 1 175 MET 175 233 233 MET MET C . n B 1 176 GLN 176 234 234 GLN GLN C . n B 1 177 LEU 177 235 235 LEU LEU C . n B 1 178 MET 178 236 236 MET MET C . n B 1 179 GLU 179 237 237 GLU GLU C . n B 1 180 GLY 180 238 238 GLY GLY C . n B 1 181 LYS 181 239 239 LYS LYS C . n B 1 182 LYS 182 240 240 LYS LYS C . n B 1 183 TYR 183 241 241 TYR TYR C . n B 1 184 CYS 184 242 242 CYS CYS C . n B 1 185 SER 185 243 243 SER SER C . n B 1 186 VAL 186 244 244 VAL VAL C . n B 1 187 LYS 187 245 245 LYS LYS C . n B 1 188 GLY 188 246 246 GLY GLY C . n B 1 189 GLU 189 247 247 GLU GLU C . n B 1 190 PRO 190 248 248 PRO PRO C . n B 1 191 PRO 191 249 249 PRO PRO C . n B 1 192 ASP 192 250 250 ASP ASP C . n B 1 193 LEU 193 251 251 LEU LEU C . n B 1 194 THR 194 252 252 THR THR C . n B 1 195 TRP 195 253 253 TRP TRP C . n B 1 196 TYR 196 254 254 TYR TYR C . n B 1 197 CYS 197 255 255 CYS CYS C . n B 1 198 PHE 198 256 256 PHE PHE C . n B 1 199 LYS 199 257 257 LYS LYS C . n B 1 200 PRO 200 258 258 PRO PRO C . n B 1 201 ARG 201 259 259 ARG ARG C . n B 1 202 LYS 202 260 260 LYS LYS C . n B 1 203 SER 203 261 261 SER SER C . n B 1 204 VAL 204 262 262 VAL VAL C . n B 1 205 THR 205 263 263 THR THR C . n B 1 206 GLU 206 264 264 GLU GLU C . n B 1 207 ASN 207 265 265 ASN ASN C . n B 1 208 HIS 208 266 266 HIS HIS C . n B 1 209 HIS 209 267 267 HIS HIS C . n B 1 210 LEU 210 268 268 LEU LEU C . n B 1 211 ILE 211 269 269 ILE ILE C . n B 1 212 TYR 212 270 270 TYR TYR C . n B 1 213 GLY 213 271 271 GLY GLY C . n B 1 214 SER 214 272 272 SER SER C . n B 1 215 ALA 215 273 273 ALA ALA C . n B 1 216 TYR 216 274 274 TYR TYR C . n B 1 217 VAL 217 275 275 VAL VAL C . n B 1 218 GLY 218 276 276 GLY GLY C . n B 1 219 GLU 219 277 277 GLU GLU C . n B 1 220 ASN 220 278 278 ASN ASN C . n B 1 221 PRO 221 279 279 PRO PRO C . n B 1 222 ASP 222 280 280 ASP ASP C . n B 1 223 ALA 223 281 281 ALA ALA C . n B 1 224 PHE 224 282 282 PHE PHE C . n B 1 225 ILE 225 283 283 ILE ILE C . n B 1 226 SER 226 284 284 SER SER C . n B 1 227 LYS 227 285 285 LYS LYS C . n B 1 228 CYS 228 286 286 CYS CYS C . n B 1 229 PRO 229 287 287 PRO PRO C . n B 1 230 ASN 230 288 288 ASN ASN C . n B 1 231 GLN 231 289 289 GLN GLN C . n B 1 232 ALA 232 290 290 ALA ALA C . n B 1 233 LEU 233 291 291 LEU LEU C . n B 1 234 ARG 234 292 292 ARG ARG C . n B 1 235 GLY 235 293 293 GLY GLY C . n B 1 236 TYR 236 294 294 TYR TYR C . n B 1 237 ARG 237 295 295 ARG ARG C . n B 1 238 PHE 238 296 296 PHE PHE C . n B 1 239 GLY 239 297 297 GLY GLY C . n B 1 240 VAL 240 298 298 VAL VAL C . n B 1 241 TRP 241 299 299 TRP TRP C . n B 1 242 LYS 242 300 300 LYS LYS C . n B 1 243 LYS 243 301 301 LYS LYS C . n B 1 244 GLY 244 302 302 GLY GLY C . n B 1 245 ARG 245 303 303 ARG ARG C . n B 1 246 CYS 246 304 304 CYS CYS C . n B 1 247 LEU 247 305 305 LEU LEU C . n B 1 248 ASP 248 306 306 ASP ASP C . n B 1 249 TYR 249 307 307 TYR TYR C . n B 1 250 THR 250 308 308 THR THR C . n B 1 251 GLU 251 309 309 GLU GLU C . n B 1 252 LEU 252 310 310 LEU LEU C . n B 1 253 THR 253 311 311 THR THR C . n B 1 254 ASP 254 312 312 ASP ASP C . n B 1 255 THR 255 313 313 THR THR C . n B 1 256 VAL 256 314 314 VAL VAL C . n B 1 257 ILE 257 315 315 ILE ILE C . n B 1 258 GLU 258 316 316 GLU GLU C . n B 1 259 ARG 259 317 317 ARG ARG C . n B 1 260 VAL 260 318 318 VAL VAL C . n B 1 261 GLU 261 319 319 GLU GLU C . n B 1 262 SER 262 320 320 SER SER C . n B 1 263 LYS 263 321 321 LYS LYS C . n B 1 264 ALA 264 322 322 ALA ALA C . n B 1 265 GLN 265 323 323 GLN GLN C . n B 1 266 CYS 266 324 324 CYS CYS C . n B 1 267 TRP 267 325 325 TRP TRP C . n B 1 268 VAL 268 326 326 VAL VAL C . n B 1 269 LYS 269 327 327 LYS LYS C . n B 1 270 THR 270 328 328 THR THR C . n B 1 271 PHE 271 329 329 PHE PHE C . n B 1 272 GLU 272 330 330 GLU GLU C . n B 1 273 ASN 273 331 331 ASN ASN C . n B 1 274 ASP 274 332 332 ASP ASP C . n B 1 275 GLY 275 333 333 GLY GLY C . n B 1 276 VAL 276 334 334 VAL VAL C . n B 1 277 ALA 277 335 335 ALA ALA C . n B 1 278 SER 278 336 336 SER SER C . n B 1 279 ASP 279 337 337 ASP ASP C . n B 1 280 GLN 280 338 338 GLN GLN C . n B 1 281 PRO 281 339 339 PRO PRO C . n B 1 282 GLY 282 353 ? ? ? C . n B 1 283 SER 283 354 ? ? ? C . n B 1 284 GLY 284 355 ? ? ? C . n B 1 285 SER 285 356 ? ? ? C . n B 1 286 GLY 286 357 ? ? ? C . n B 1 287 SER 287 358 ? ? ? C . n B 1 288 GLY 288 359 ? ? ? C . n B 1 289 ASP 289 360 360 ASP ASP C . n B 1 290 GLN 290 361 361 GLN GLN C . n B 1 291 PRO 291 362 362 PRO PRO C . n B 1 292 HIS 292 363 363 HIS HIS C . n B 1 293 SER 293 364 364 SER SER C . n B 1 294 GLY 294 365 365 GLY GLY C . n B 1 295 GLY 295 366 366 GLY GLY C . n B 1 296 VAL 296 367 367 VAL VAL C . n B 1 297 GLY 297 368 368 GLY GLY C . n B 1 298 ARG 298 369 369 ARG ARG C . n B 1 299 ASN 299 370 370 ASN ASN C . n B 1 300 TYR 300 371 371 TYR TYR C . n B 1 301 GLY 301 372 372 GLY GLY C . n B 1 302 PHE 302 373 373 PHE PHE C . n B 1 303 TYR 303 374 374 TYR TYR C . n B 1 304 TYR 304 375 375 TYR TYR C . n B 1 305 VAL 305 376 376 VAL VAL C . n B 1 306 ASP 306 377 377 ASP ASP C . n B 1 307 THR 307 378 378 THR THR C . n B 1 308 THR 308 379 379 THR THR C . n B 1 309 GLY 309 380 380 GLY GLY C . n B 1 310 GLU 310 381 381 GLU GLU C . n B 1 311 GLY 311 382 382 GLY GLY C . n B 1 312 LYS 312 383 383 LYS LYS C . n B 1 313 CYS 313 384 384 CYS CYS C . n B 1 314 ALA 314 385 385 ALA ALA C . n B 1 315 LEU 315 386 386 LEU LEU C . n B 1 316 SER 316 387 387 SER SER C . n B 1 317 ASP 317 388 388 ASP ASP C . n B 1 318 GLN 318 389 389 GLN GLN C . n B 1 319 VAL 319 390 390 VAL VAL C . n B 1 320 PRO 320 391 391 PRO PRO C . n B 1 321 ASP 321 392 392 ASP ASP C . n B 1 322 CYS 322 393 393 CYS CYS C . n B 1 323 LEU 323 394 394 LEU LEU C . n B 1 324 VAL 324 395 395 VAL VAL C . n B 1 325 SER 325 396 396 SER SER C . n B 1 326 ASP 326 397 397 ASP ASP C . n B 1 327 SER 327 398 398 SER SER C . n B 1 328 ALA 328 399 399 ALA ALA C . n B 1 329 ALA 329 400 400 ALA ALA C . n B 1 330 VAL 330 401 401 VAL VAL C . n B 1 331 SER 331 402 402 SER SER C . n B 1 332 TYR 332 403 403 TYR TYR C . n B 1 333 THR 333 404 404 THR THR C . n B 1 334 ALA 334 405 405 ALA ALA C . n B 1 335 ALA 335 406 406 ALA ALA C . n B 1 336 GLY 336 407 407 GLY GLY C . n B 1 337 SER 337 408 408 SER SER C . n B 1 338 LEU 338 409 409 LEU LEU C . n B 1 339 SER 339 410 410 SER SER C . n B 1 340 GLU 340 411 411 GLU GLU C . n B 1 341 GLU 341 412 412 GLU GLU C . n B 1 342 THR 342 413 413 THR THR C . n B 1 343 PRO 343 414 414 PRO PRO C . n B 1 344 ASN 344 415 415 ASN ASN C . n B 1 345 PHE 345 416 416 PHE PHE C . n B 1 346 ILE 346 417 417 ILE ILE C . n B 1 347 ILE 347 418 418 ILE ILE C . n B 1 348 PRO 348 419 419 PRO PRO C . n B 1 349 SER 349 420 420 SER SER C . n B 1 350 ASN 350 421 421 ASN ASN C . n B 1 351 PRO 351 422 422 PRO PRO C . n B 1 352 SER 352 423 423 SER SER C . n B 1 353 VAL 353 424 424 VAL VAL C . n B 1 354 THR 354 425 425 THR THR C . n B 1 355 PRO 355 426 426 PRO PRO C . n B 1 356 PRO 356 427 427 PRO PRO C . n B 1 357 THR 357 428 428 THR THR C . n B 1 358 PRO 358 429 429 PRO PRO C . n B 1 359 GLU 359 430 430 GLU GLU C . n B 1 360 THR 360 431 431 THR THR C . n B 1 361 ALA 361 432 432 ALA ALA C . n B 1 362 LEU 362 433 433 LEU LEU C . n B 1 363 GLN 363 434 434 GLN GLN C . n B 1 364 CYS 364 435 435 CYS CYS C . n B 1 365 THR 365 436 436 THR THR C . n B 1 366 ALA 366 437 437 ALA ALA C . n B 1 367 ASP 367 438 438 ASP ASP C . n B 1 368 LYS 368 439 439 LYS LYS C . n B 1 369 PHE 369 440 440 PHE PHE C . n B 1 370 PRO 370 441 441 PRO PRO C . n B 1 371 ASP 371 442 442 ASP ASP C . n B 1 372 SER 372 443 443 SER SER C . n B 1 373 PHE 373 444 444 PHE PHE C . n B 1 374 GLY 374 445 445 GLY GLY C . n B 1 375 ALA 375 446 446 ALA ALA C . n B 1 376 CYS 376 447 447 CYS CYS C . n B 1 377 ASP 377 448 448 ASP ASP C . n B 1 378 VAL 378 449 449 VAL VAL C . n B 1 379 GLN 379 450 450 GLN GLN C . n B 1 380 ALA 380 451 451 ALA ALA C . n B 1 381 CYS 381 452 452 CYS CYS C . n B 1 382 LYS 382 453 453 LYS LYS C . n B 1 383 ARG 383 454 454 ARG ARG C . n B 1 384 GLN 384 455 455 GLN GLN C . n B 1 385 LYS 385 456 456 LYS LYS C . n B 1 386 THR 386 457 457 THR THR C . n B 1 387 SER 387 458 458 SER SER C . n B 1 388 CYS 388 459 459 CYS CYS C . n B 1 389 VAL 389 460 460 VAL VAL C . n B 1 390 GLY 390 461 461 GLY GLY C . n B 1 391 GLY 391 462 462 GLY GLY C . n B 1 392 GLN 392 463 463 GLN GLN C . n B 1 393 ILE 393 464 464 ILE ILE C . n B 1 394 GLN 394 465 465 GLN GLN C . n B 1 395 SER 395 466 466 SER SER C . n B 1 396 THR 396 467 467 THR THR C . n B 1 397 SER 397 468 468 SER SER C . n B 1 398 VAL 398 469 469 VAL VAL C . n B 1 399 ASP 399 470 470 ASP ASP C . n B 1 400 CYS 400 471 471 CYS CYS C . n B 1 401 THR 401 472 472 THR THR C . n B 1 402 ALA 402 473 473 ALA ALA C . n B 1 403 ASP 403 474 474 ASP ASP C . n B 1 404 GLU 404 475 475 GLU GLU C . n B 1 405 GLN 405 476 476 GLN GLN C . n B 1 406 ASN 406 477 477 ASN ASN C . n B 1 407 GLU 407 478 478 GLU GLU C . n B 1 408 CYS 408 479 479 CYS CYS C . n B 1 409 GLY 409 480 ? ? ? C . n B 1 410 SER 410 481 ? ? ? C . n B 1 411 ASN 411 482 ? ? ? C . n B 1 412 THR 412 483 ? ? ? C . n B 1 413 ALA 413 484 ? ? ? C . n B 1 414 ALA 414 485 ? ? ? C . n B 1 415 ALA 415 486 ? ? ? C . n B 1 416 LEU 416 487 ? ? ? C . n B 1 417 VAL 417 488 ? ? ? C . n B 1 418 PRO 418 489 ? ? ? C . n B 1 419 ARG 419 490 ? ? ? C . n C 1 1 GLY 1 59 ? ? ? E . n C 1 2 SER 2 60 ? ? ? E . n C 1 3 ALA 3 61 ? ? ? E . n C 1 4 MET 4 62 ? ? ? E . n C 1 5 GLY 5 63 ? ? ? E . n C 1 6 SER 6 64 ? ? ? E . n C 1 7 ALA 7 65 ? ? ? E . n C 1 8 SER 8 66 ? ? ? E . n C 1 9 THR 9 67 ? ? ? E . n C 1 10 SER 10 68 68 SER SER E . n C 1 11 GLY 11 69 69 GLY GLY E . n C 1 12 ASN 12 70 70 ASN ASN E . n C 1 13 PRO 13 71 71 PRO PRO E . n C 1 14 PHE 14 72 72 PHE PHE E . n C 1 15 GLN 15 73 73 GLN GLN E . n C 1 16 ALA 16 74 74 ALA ALA E . n C 1 17 ASN 17 75 75 ASN ASN E . n C 1 18 VAL 18 76 76 VAL VAL E . n C 1 19 GLU 19 77 77 GLU GLU E . n C 1 20 MET 20 78 78 MET MET E . n C 1 21 LYS 21 79 79 LYS LYS E . n C 1 22 THR 22 80 80 THR THR E . n C 1 23 PHE 23 81 81 PHE PHE E . n C 1 24 MET 24 82 82 MET MET E . n C 1 25 GLU 25 83 83 GLU GLU E . n C 1 26 ARG 26 84 84 ARG ARG E . n C 1 27 PHE 27 85 85 PHE PHE E . n C 1 28 ASN 28 86 86 ASN ASN E . n C 1 29 LEU 29 87 87 LEU LEU E . n C 1 30 THR 30 88 88 THR THR E . n C 1 31 HIS 31 89 89 HIS HIS E . n C 1 32 HIS 32 90 90 HIS HIS E . n C 1 33 HIS 33 91 91 HIS HIS E . n C 1 34 GLN 34 92 92 GLN GLN E . n C 1 35 SER 35 93 93 SER SER E . n C 1 36 GLY 36 94 94 GLY GLY E . n C 1 37 ILE 37 95 95 ILE ILE E . n C 1 38 TYR 38 96 96 TYR TYR E . n C 1 39 VAL 39 97 97 VAL VAL E . n C 1 40 ASP 40 98 98 ASP ASP E . n C 1 41 LEU 41 99 99 LEU LEU E . n C 1 42 GLY 42 100 100 GLY GLY E . n C 1 43 GLN 43 101 101 GLN GLN E . n C 1 44 ASP 44 102 102 ASP ASP E . n C 1 45 LYS 45 103 103 LYS LYS E . n C 1 46 GLU 46 104 104 GLU GLU E . n C 1 47 VAL 47 105 105 VAL VAL E . n C 1 48 ASP 48 106 106 ASP ASP E . n C 1 49 GLY 49 107 107 GLY GLY E . n C 1 50 THR 50 108 108 THR THR E . n C 1 51 LEU 51 109 109 LEU LEU E . n C 1 52 TYR 52 110 110 TYR TYR E . n C 1 53 ARG 53 111 111 ARG ARG E . n C 1 54 GLU 54 112 112 GLU GLU E . n C 1 55 PRO 55 113 113 PRO PRO E . n C 1 56 ALA 56 114 114 ALA ALA E . n C 1 57 GLY 57 115 115 GLY GLY E . n C 1 58 LEU 58 116 116 LEU LEU E . n C 1 59 CYS 59 117 117 CYS CYS E . n C 1 60 PRO 60 118 118 PRO PRO E . n C 1 61 ILE 61 119 119 ILE ILE E . n C 1 62 TRP 62 120 120 TRP TRP E . n C 1 63 GLY 63 121 121 GLY GLY E . n C 1 64 LYS 64 122 122 LYS LYS E . n C 1 65 HIS 65 123 123 HIS HIS E . n C 1 66 ILE 66 124 124 ILE ILE E . n C 1 67 GLU 67 125 125 GLU GLU E . n C 1 68 LEU 68 126 126 LEU LEU E . n C 1 69 GLN 69 127 127 GLN GLN E . n C 1 70 GLN 70 128 128 GLN GLN E . n C 1 71 PRO 71 129 129 PRO PRO E . n C 1 72 ASP 72 130 130 ASP ASP E . n C 1 73 ARG 73 131 131 ARG ARG E . n C 1 74 PRO 74 132 132 PRO PRO E . n C 1 75 PRO 75 133 133 PRO PRO E . n C 1 76 TYR 76 134 134 TYR TYR E . n C 1 77 ARG 77 135 135 ARG ARG E . n C 1 78 ASN 78 136 136 ASN ASN E . n C 1 79 ASN 79 137 137 ASN ASN E . n C 1 80 PHE 80 138 138 PHE PHE E . n C 1 81 LEU 81 139 139 LEU LEU E . n C 1 82 GLU 82 140 140 GLU GLU E . n C 1 83 ASP 83 141 141 ASP ASP E . n C 1 84 VAL 84 142 142 VAL VAL E . n C 1 85 PRO 85 143 143 PRO PRO E . n C 1 86 THR 86 144 144 THR THR E . n C 1 87 GLU 87 145 145 GLU GLU E . n C 1 88 LYS 88 146 146 LYS LYS E . n C 1 89 GLU 89 147 147 GLU GLU E . n C 1 90 TYR 90 148 148 TYR TYR E . n C 1 91 LYS 91 149 149 LYS LYS E . n C 1 92 GLN 92 150 150 GLN GLN E . n C 1 93 SER 93 151 151 SER SER E . n C 1 94 GLY 94 152 152 GLY GLY E . n C 1 95 ASN 95 153 153 ASN ASN E . n C 1 96 PRO 96 154 154 PRO PRO E . n C 1 97 LEU 97 155 155 LEU LEU E . n C 1 98 PRO 98 156 156 PRO PRO E . n C 1 99 GLY 99 157 157 GLY GLY E . n C 1 100 GLY 100 158 158 GLY GLY E . n C 1 101 PHE 101 159 159 PHE PHE E . n C 1 102 ASN 102 160 160 ASN ASN E . n C 1 103 LEU 103 161 161 LEU LEU E . n C 1 104 ASN 104 162 162 ASN ASN E . n C 1 105 PHE 105 163 163 PHE PHE E . n C 1 106 VAL 106 164 164 VAL VAL E . n C 1 107 THR 107 165 165 THR THR E . n C 1 108 PRO 108 166 166 PRO PRO E . n C 1 109 SER 109 167 167 SER SER E . n C 1 110 GLY 110 168 168 GLY GLY E . n C 1 111 GLN 111 169 169 GLN GLN E . n C 1 112 ARG 112 170 170 ARG ARG E . n C 1 113 ILE 113 171 171 ILE ILE E . n C 1 114 SER 114 172 172 SER SER E . n C 1 115 PRO 115 173 173 PRO PRO E . n C 1 116 PHE 116 174 174 PHE PHE E . n C 1 117 PRO 117 175 175 PRO PRO E . n C 1 118 MET 118 176 176 MET MET E . n C 1 119 GLU 119 177 177 GLU GLU E . n C 1 120 LEU 120 178 178 LEU LEU E . n C 1 121 LEU 121 179 179 LEU LEU E . n C 1 122 GLU 122 180 180 GLU GLU E . n C 1 123 LYS 123 181 181 LYS LYS E . n C 1 124 ASN 124 182 182 ASN ASN E . n C 1 125 SER 125 183 183 SER SER E . n C 1 126 ASN 126 184 184 ASN ASN E . n C 1 127 ILE 127 185 185 ILE ILE E . n C 1 128 LYS 128 186 186 LYS LYS E . n C 1 129 ALA 129 187 187 ALA ALA E . n C 1 130 SER 130 188 188 SER SER E . n C 1 131 THR 131 189 189 THR THR E . n C 1 132 ASP 132 190 190 ASP ASP E . n C 1 133 LEU 133 191 191 LEU LEU E . n C 1 134 GLY 134 192 192 GLY GLY E . n C 1 135 ARG 135 193 193 ARG ARG E . n C 1 136 CYS 136 194 194 CYS CYS E . n C 1 137 ALA 137 195 195 ALA ALA E . n C 1 138 GLU 138 196 196 GLU GLU E . n C 1 139 PHE 139 197 197 PHE PHE E . n C 1 140 ALA 140 198 198 ALA ALA E . n C 1 141 PHE 141 199 199 PHE PHE E . n C 1 142 LYS 142 200 200 LYS LYS E . n C 1 143 THR 143 201 201 THR THR E . n C 1 144 VAL 144 202 202 VAL VAL E . n C 1 145 ALA 145 203 203 ALA ALA E . n C 1 146 MET 146 204 204 MET MET E . n C 1 147 ASP 147 205 205 ASP ASP E . n C 1 148 LYS 148 206 206 LYS LYS E . n C 1 149 ASN 149 207 207 ASN ASN E . n C 1 150 ASN 150 208 208 ASN ASN E . n C 1 151 LYS 151 209 209 LYS LYS E . n C 1 152 ALA 152 210 210 ALA ALA E . n C 1 153 THR 153 211 211 THR THR E . n C 1 154 LYS 154 212 212 LYS LYS E . n C 1 155 TYR 155 213 213 TYR TYR E . n C 1 156 ARG 156 214 214 ARG ARG E . n C 1 157 TYR 157 215 215 TYR TYR E . n C 1 158 PRO 158 216 216 PRO PRO E . n C 1 159 PHE 159 217 217 PHE PHE E . n C 1 160 VAL 160 218 218 VAL VAL E . n C 1 161 TYR 161 219 219 TYR TYR E . n C 1 162 ASP 162 220 220 ASP ASP E . n C 1 163 SER 163 221 221 SER SER E . n C 1 164 LYS 164 222 222 LYS LYS E . n C 1 165 LYS 165 223 223 LYS LYS E . n C 1 166 ARG 166 224 224 ARG ARG E . n C 1 167 LEU 167 225 225 LEU LEU E . n C 1 168 CYS 168 226 226 CYS CYS E . n C 1 169 HIS 169 227 227 HIS HIS E . n C 1 170 ILE 170 228 228 ILE ILE E . n C 1 171 LEU 171 229 229 LEU LEU E . n C 1 172 TYR 172 230 230 TYR TYR E . n C 1 173 VAL 173 231 231 VAL VAL E . n C 1 174 SER 174 232 232 SER SER E . n C 1 175 MET 175 233 233 MET MET E . n C 1 176 GLN 176 234 234 GLN GLN E . n C 1 177 LEU 177 235 235 LEU LEU E . n C 1 178 MET 178 236 236 MET MET E . n C 1 179 GLU 179 237 237 GLU GLU E . n C 1 180 GLY 180 238 238 GLY GLY E . n C 1 181 LYS 181 239 239 LYS LYS E . n C 1 182 LYS 182 240 240 LYS LYS E . n C 1 183 TYR 183 241 241 TYR TYR E . n C 1 184 CYS 184 242 242 CYS CYS E . n C 1 185 SER 185 243 243 SER SER E . n C 1 186 VAL 186 244 244 VAL VAL E . n C 1 187 LYS 187 245 245 LYS LYS E . n C 1 188 GLY 188 246 246 GLY GLY E . n C 1 189 GLU 189 247 247 GLU GLU E . n C 1 190 PRO 190 248 248 PRO PRO E . n C 1 191 PRO 191 249 249 PRO PRO E . n C 1 192 ASP 192 250 250 ASP ASP E . n C 1 193 LEU 193 251 251 LEU LEU E . n C 1 194 THR 194 252 252 THR THR E . n C 1 195 TRP 195 253 253 TRP TRP E . n C 1 196 TYR 196 254 254 TYR TYR E . n C 1 197 CYS 197 255 255 CYS CYS E . n C 1 198 PHE 198 256 256 PHE PHE E . n C 1 199 LYS 199 257 257 LYS LYS E . n C 1 200 PRO 200 258 258 PRO PRO E . n C 1 201 ARG 201 259 259 ARG ARG E . n C 1 202 LYS 202 260 260 LYS LYS E . n C 1 203 SER 203 261 261 SER SER E . n C 1 204 VAL 204 262 262 VAL VAL E . n C 1 205 THR 205 263 263 THR THR E . n C 1 206 GLU 206 264 264 GLU GLU E . n C 1 207 ASN 207 265 265 ASN ASN E . n C 1 208 HIS 208 266 266 HIS HIS E . n C 1 209 HIS 209 267 267 HIS HIS E . n C 1 210 LEU 210 268 268 LEU LEU E . n C 1 211 ILE 211 269 269 ILE ILE E . n C 1 212 TYR 212 270 270 TYR TYR E . n C 1 213 GLY 213 271 271 GLY GLY E . n C 1 214 SER 214 272 272 SER SER E . n C 1 215 ALA 215 273 273 ALA ALA E . n C 1 216 TYR 216 274 274 TYR TYR E . n C 1 217 VAL 217 275 275 VAL VAL E . n C 1 218 GLY 218 276 276 GLY GLY E . n C 1 219 GLU 219 277 277 GLU GLU E . n C 1 220 ASN 220 278 278 ASN ASN E . n C 1 221 PRO 221 279 279 PRO PRO E . n C 1 222 ASP 222 280 280 ASP ASP E . n C 1 223 ALA 223 281 281 ALA ALA E . n C 1 224 PHE 224 282 282 PHE PHE E . n C 1 225 ILE 225 283 283 ILE ILE E . n C 1 226 SER 226 284 284 SER SER E . n C 1 227 LYS 227 285 285 LYS LYS E . n C 1 228 CYS 228 286 286 CYS CYS E . n C 1 229 PRO 229 287 287 PRO PRO E . n C 1 230 ASN 230 288 288 ASN ASN E . n C 1 231 GLN 231 289 289 GLN GLN E . n C 1 232 ALA 232 290 290 ALA ALA E . n C 1 233 LEU 233 291 291 LEU LEU E . n C 1 234 ARG 234 292 292 ARG ARG E . n C 1 235 GLY 235 293 293 GLY GLY E . n C 1 236 TYR 236 294 294 TYR TYR E . n C 1 237 ARG 237 295 295 ARG ARG E . n C 1 238 PHE 238 296 296 PHE PHE E . n C 1 239 GLY 239 297 297 GLY GLY E . n C 1 240 VAL 240 298 298 VAL VAL E . n C 1 241 TRP 241 299 299 TRP TRP E . n C 1 242 LYS 242 300 300 LYS LYS E . n C 1 243 LYS 243 301 301 LYS LYS E . n C 1 244 GLY 244 302 302 GLY GLY E . n C 1 245 ARG 245 303 303 ARG ARG E . n C 1 246 CYS 246 304 304 CYS CYS E . n C 1 247 LEU 247 305 305 LEU LEU E . n C 1 248 ASP 248 306 306 ASP ASP E . n C 1 249 TYR 249 307 307 TYR TYR E . n C 1 250 THR 250 308 308 THR THR E . n C 1 251 GLU 251 309 309 GLU GLU E . n C 1 252 LEU 252 310 310 LEU LEU E . n C 1 253 THR 253 311 311 THR THR E . n C 1 254 ASP 254 312 312 ASP ASP E . n C 1 255 THR 255 313 313 THR THR E . n C 1 256 VAL 256 314 314 VAL VAL E . n C 1 257 ILE 257 315 315 ILE ILE E . n C 1 258 GLU 258 316 316 GLU GLU E . n C 1 259 ARG 259 317 317 ARG ARG E . n C 1 260 VAL 260 318 318 VAL VAL E . n C 1 261 GLU 261 319 319 GLU GLU E . n C 1 262 SER 262 320 320 SER SER E . n C 1 263 LYS 263 321 321 LYS LYS E . n C 1 264 ALA 264 322 322 ALA ALA E . n C 1 265 GLN 265 323 323 GLN GLN E . n C 1 266 CYS 266 324 324 CYS CYS E . n C 1 267 TRP 267 325 325 TRP TRP E . n C 1 268 VAL 268 326 326 VAL VAL E . n C 1 269 LYS 269 327 327 LYS LYS E . n C 1 270 THR 270 328 328 THR THR E . n C 1 271 PHE 271 329 329 PHE PHE E . n C 1 272 GLU 272 330 330 GLU GLU E . n C 1 273 ASN 273 331 331 ASN ASN E . n C 1 274 ASP 274 332 332 ASP ASP E . n C 1 275 GLY 275 333 333 GLY GLY E . n C 1 276 VAL 276 334 334 VAL VAL E . n C 1 277 ALA 277 335 335 ALA ALA E . n C 1 278 SER 278 336 336 SER SER E . n C 1 279 ASP 279 337 337 ASP ASP E . n C 1 280 GLN 280 338 338 GLN GLN E . n C 1 281 PRO 281 339 339 PRO PRO E . n C 1 282 GLY 282 353 ? ? ? E . n C 1 283 SER 283 354 ? ? ? E . n C 1 284 GLY 284 355 ? ? ? E . n C 1 285 SER 285 356 ? ? ? E . n C 1 286 GLY 286 357 ? ? ? E . n C 1 287 SER 287 358 ? ? ? E . n C 1 288 GLY 288 359 ? ? ? E . n C 1 289 ASP 289 360 360 ASP ASP E . n C 1 290 GLN 290 361 361 GLN GLN E . n C 1 291 PRO 291 362 362 PRO PRO E . n C 1 292 HIS 292 363 363 HIS HIS E . n C 1 293 SER 293 364 364 SER SER E . n C 1 294 GLY 294 365 365 GLY GLY E . n C 1 295 GLY 295 366 366 GLY GLY E . n C 1 296 VAL 296 367 367 VAL VAL E . n C 1 297 GLY 297 368 368 GLY GLY E . n C 1 298 ARG 298 369 369 ARG ARG E . n C 1 299 ASN 299 370 370 ASN ASN E . n C 1 300 TYR 300 371 371 TYR TYR E . n C 1 301 GLY 301 372 372 GLY GLY E . n C 1 302 PHE 302 373 373 PHE PHE E . n C 1 303 TYR 303 374 374 TYR TYR E . n C 1 304 TYR 304 375 375 TYR TYR E . n C 1 305 VAL 305 376 376 VAL VAL E . n C 1 306 ASP 306 377 377 ASP ASP E . n C 1 307 THR 307 378 378 THR THR E . n C 1 308 THR 308 379 379 THR THR E . n C 1 309 GLY 309 380 380 GLY GLY E . n C 1 310 GLU 310 381 381 GLU GLU E . n C 1 311 GLY 311 382 382 GLY GLY E . n C 1 312 LYS 312 383 383 LYS LYS E . n C 1 313 CYS 313 384 384 CYS CYS E . n C 1 314 ALA 314 385 385 ALA ALA E . n C 1 315 LEU 315 386 386 LEU LEU E . n C 1 316 SER 316 387 387 SER SER E . n C 1 317 ASP 317 388 388 ASP ASP E . n C 1 318 GLN 318 389 389 GLN GLN E . n C 1 319 VAL 319 390 390 VAL VAL E . n C 1 320 PRO 320 391 391 PRO PRO E . n C 1 321 ASP 321 392 392 ASP ASP E . n C 1 322 CYS 322 393 393 CYS CYS E . n C 1 323 LEU 323 394 394 LEU LEU E . n C 1 324 VAL 324 395 395 VAL VAL E . n C 1 325 SER 325 396 396 SER SER E . n C 1 326 ASP 326 397 397 ASP ASP E . n C 1 327 SER 327 398 398 SER SER E . n C 1 328 ALA 328 399 399 ALA ALA E . n C 1 329 ALA 329 400 400 ALA ALA E . n C 1 330 VAL 330 401 401 VAL VAL E . n C 1 331 SER 331 402 402 SER SER E . n C 1 332 TYR 332 403 403 TYR TYR E . n C 1 333 THR 333 404 404 THR THR E . n C 1 334 ALA 334 405 405 ALA ALA E . n C 1 335 ALA 335 406 406 ALA ALA E . n C 1 336 GLY 336 407 407 GLY GLY E . n C 1 337 SER 337 408 408 SER SER E . n C 1 338 LEU 338 409 409 LEU LEU E . n C 1 339 SER 339 410 410 SER SER E . n C 1 340 GLU 340 411 411 GLU GLU E . n C 1 341 GLU 341 412 412 GLU GLU E . n C 1 342 THR 342 413 413 THR THR E . n C 1 343 PRO 343 414 414 PRO PRO E . n C 1 344 ASN 344 415 415 ASN ASN E . n C 1 345 PHE 345 416 416 PHE PHE E . n C 1 346 ILE 346 417 417 ILE ILE E . n C 1 347 ILE 347 418 418 ILE ILE E . n C 1 348 PRO 348 419 419 PRO PRO E . n C 1 349 SER 349 420 420 SER SER E . n C 1 350 ASN 350 421 421 ASN ASN E . n C 1 351 PRO 351 422 ? ? ? E . n C 1 352 SER 352 423 ? ? ? E . n C 1 353 VAL 353 424 ? ? ? E . n C 1 354 THR 354 425 ? ? ? E . n C 1 355 PRO 355 426 ? ? ? E . n C 1 356 PRO 356 427 427 PRO PRO E . n C 1 357 THR 357 428 428 THR THR E . n C 1 358 PRO 358 429 429 PRO PRO E . n C 1 359 GLU 359 430 430 GLU GLU E . n C 1 360 THR 360 431 431 THR THR E . n C 1 361 ALA 361 432 432 ALA ALA E . n C 1 362 LEU 362 433 433 LEU LEU E . n C 1 363 GLN 363 434 434 GLN GLN E . n C 1 364 CYS 364 435 435 CYS CYS E . n C 1 365 THR 365 436 436 THR THR E . n C 1 366 ALA 366 437 437 ALA ALA E . n C 1 367 ASP 367 438 438 ASP ASP E . n C 1 368 LYS 368 439 439 LYS LYS E . n C 1 369 PHE 369 440 440 PHE PHE E . n C 1 370 PRO 370 441 441 PRO PRO E . n C 1 371 ASP 371 442 442 ASP ASP E . n C 1 372 SER 372 443 443 SER SER E . n C 1 373 PHE 373 444 444 PHE PHE E . n C 1 374 GLY 374 445 445 GLY GLY E . n C 1 375 ALA 375 446 446 ALA ALA E . n C 1 376 CYS 376 447 447 CYS CYS E . n C 1 377 ASP 377 448 448 ASP ASP E . n C 1 378 VAL 378 449 449 VAL VAL E . n C 1 379 GLN 379 450 450 GLN GLN E . n C 1 380 ALA 380 451 451 ALA ALA E . n C 1 381 CYS 381 452 452 CYS CYS E . n C 1 382 LYS 382 453 453 LYS LYS E . n C 1 383 ARG 383 454 454 ARG ARG E . n C 1 384 GLN 384 455 455 GLN GLN E . n C 1 385 LYS 385 456 456 LYS LYS E . n C 1 386 THR 386 457 457 THR THR E . n C 1 387 SER 387 458 458 SER SER E . n C 1 388 CYS 388 459 459 CYS CYS E . n C 1 389 VAL 389 460 460 VAL VAL E . n C 1 390 GLY 390 461 461 GLY GLY E . n C 1 391 GLY 391 462 462 GLY GLY E . n C 1 392 GLN 392 463 463 GLN GLN E . n C 1 393 ILE 393 464 464 ILE ILE E . n C 1 394 GLN 394 465 465 GLN GLN E . n C 1 395 SER 395 466 466 SER SER E . n C 1 396 THR 396 467 467 THR THR E . n C 1 397 SER 397 468 468 SER SER E . n C 1 398 VAL 398 469 469 VAL VAL E . n C 1 399 ASP 399 470 470 ASP ASP E . n C 1 400 CYS 400 471 471 CYS CYS E . n C 1 401 THR 401 472 472 THR THR E . n C 1 402 ALA 402 473 473 ALA ALA E . n C 1 403 ASP 403 474 474 ASP ASP E . n C 1 404 GLU 404 475 475 GLU GLU E . n C 1 405 GLN 405 476 476 GLN GLN E . n C 1 406 ASN 406 477 477 ASN ASN E . n C 1 407 GLU 407 478 478 GLU GLU E . n C 1 408 CYS 408 479 479 CYS CYS E . n C 1 409 GLY 409 480 480 GLY GLY E . n C 1 410 SER 410 481 ? ? ? E . n C 1 411 ASN 411 482 ? ? ? E . n C 1 412 THR 412 483 ? ? ? E . n C 1 413 ALA 413 484 ? ? ? E . n C 1 414 ALA 414 485 ? ? ? E . n C 1 415 ALA 415 486 ? ? ? E . n C 1 416 LEU 416 487 ? ? ? E . n C 1 417 VAL 417 488 ? ? ? E . n C 1 418 PRO 418 489 ? ? ? E . n C 1 419 ARG 419 490 ? ? ? E . n D 2 1 GLY 1 1258 ? ? ? B . n D 2 2 SER 2 1259 1259 SER SER B . n D 2 3 ALA 3 1260 1260 ALA ALA B . n D 2 4 SER 4 1261 1261 SER SER B . n D 2 5 ASP 5 1262 1262 ASP ASP B . n D 2 6 ILE 6 1263 1263 ILE ILE B . n D 2 7 THR 7 1264 1264 THR THR B . n D 2 8 GLN 8 1265 1265 GLN GLN B . n D 2 9 HIS 9 1266 1266 HIS HIS B . n D 2 10 LEU 10 1267 1267 LEU LEU B . n D 2 11 ASN 11 1268 1268 ASN ASN B . n D 2 12 ASP 12 1269 1269 ASP ASP B . n D 2 13 SER 13 1270 1270 SER SER B . n D 2 14 GLY 14 1271 1271 GLY GLY B . n D 2 15 LEU 15 1272 1272 LEU LEU B . n D 2 16 GLY 16 1273 1273 GLY GLY B . n D 2 17 PRO 17 1274 1274 PRO PRO B . n D 2 18 ALA 18 1275 1275 ALA ALA B . n D 2 19 VAL 19 1276 1276 VAL VAL B . n D 2 20 GLU 20 1277 1277 GLU GLU B . n D 2 21 CYS 21 1278 1278 CYS CYS B . n D 2 22 LEU 22 1279 1279 LEU LEU B . n D 2 23 GLU 23 1280 1280 GLU GLU B . n D 2 24 ASN 24 1281 1281 ASN ASN B . n D 2 25 LEU 25 1282 1282 LEU LEU B . n D 2 26 VAL 26 1283 1283 VAL VAL B . n D 2 27 VAL 27 1284 1284 VAL VAL B . n D 2 28 GLY 28 1285 1285 GLY GLY B . n D 2 29 PRO 29 1286 1286 PRO PRO B . n D 2 30 VAL 30 1287 1287 VAL VAL B . n D 2 31 CYS 31 1288 1288 CYS CYS B . n D 2 32 PRO 32 1289 1289 PRO PRO B . n D 2 33 ALA 33 1290 1290 ALA ALA B . n D 2 34 ALA 34 1291 1291 ALA ALA B . n D 2 35 VAL 35 1292 1292 VAL VAL B . n D 2 36 VAL 36 1293 1293 VAL VAL B . n D 2 37 ALA 37 1294 1294 ALA ALA B . n D 2 38 PRO 38 1295 1295 PRO PRO B . n D 2 39 ALA 39 1296 1296 ALA ALA B . n D 2 40 VAL 40 1297 1297 VAL VAL B . n E 2 1 GLY 1 1258 ? ? ? D . n E 2 2 SER 2 1259 1259 SER SER D . n E 2 3 ALA 3 1260 1260 ALA ALA D . n E 2 4 SER 4 1261 1261 SER SER D . n E 2 5 ASP 5 1262 1262 ASP ASP D . n E 2 6 ILE 6 1263 1263 ILE ILE D . n E 2 7 THR 7 1264 1264 THR THR D . n E 2 8 GLN 8 1265 1265 GLN GLN D . n E 2 9 HIS 9 1266 1266 HIS HIS D . n E 2 10 LEU 10 1267 1267 LEU LEU D . n E 2 11 ASN 11 1268 1268 ASN ASN D . n E 2 12 ASP 12 1269 1269 ASP ASP D . n E 2 13 SER 13 1270 1270 SER SER D . n E 2 14 GLY 14 1271 1271 GLY GLY D . n E 2 15 LEU 15 1272 1272 LEU LEU D . n E 2 16 GLY 16 1273 1273 GLY GLY D . n E 2 17 PRO 17 1274 1274 PRO PRO D . n E 2 18 ALA 18 1275 1275 ALA ALA D . n E 2 19 VAL 19 1276 1276 VAL VAL D . n E 2 20 GLU 20 1277 1277 GLU GLU D . n E 2 21 CYS 21 1278 1278 CYS CYS D . n E 2 22 LEU 22 1279 1279 LEU LEU D . n E 2 23 GLU 23 1280 1280 GLU GLU D . n E 2 24 ASN 24 1281 1281 ASN ASN D . n E 2 25 LEU 25 1282 1282 LEU LEU D . n E 2 26 VAL 26 1283 1283 VAL VAL D . n E 2 27 VAL 27 1284 1284 VAL VAL D . n E 2 28 GLY 28 1285 1285 GLY GLY D . n E 2 29 PRO 29 1286 1286 PRO PRO D . n E 2 30 VAL 30 1287 1287 VAL VAL D . n E 2 31 CYS 31 1288 1288 CYS CYS D . n E 2 32 PRO 32 1289 1289 PRO PRO D . n E 2 33 ALA 33 1290 1290 ALA ALA D . n E 2 34 ALA 34 1291 1291 ALA ALA D . n E 2 35 VAL 35 1292 1292 VAL VAL D . n E 2 36 VAL 36 1293 1293 VAL VAL D . n E 2 37 ALA 37 1294 1294 ALA ALA D . n E 2 38 PRO 38 1295 1295 PRO PRO D . n E 2 39 ALA 39 1296 1296 ALA ALA D . n E 2 40 VAL 40 1297 1297 VAL VAL D . n F 2 1 GLY 1 1258 ? ? ? F . n F 2 2 SER 2 1259 1259 SER SER F . n F 2 3 ALA 3 1260 1260 ALA ALA F . n F 2 4 SER 4 1261 1261 SER SER F . n F 2 5 ASP 5 1262 1262 ASP ASP F . n F 2 6 ILE 6 1263 1263 ILE ILE F . n F 2 7 THR 7 1264 1264 THR THR F . n F 2 8 GLN 8 1265 1265 GLN GLN F . n F 2 9 HIS 9 1266 1266 HIS HIS F . n F 2 10 LEU 10 1267 1267 LEU LEU F . n F 2 11 ASN 11 1268 1268 ASN ASN F . n F 2 12 ASP 12 1269 1269 ASP ASP F . n F 2 13 SER 13 1270 1270 SER SER F . n F 2 14 GLY 14 1271 1271 GLY GLY F . n F 2 15 LEU 15 1272 1272 LEU LEU F . n F 2 16 GLY 16 1273 1273 GLY GLY F . n F 2 17 PRO 17 1274 1274 PRO PRO F . n F 2 18 ALA 18 1275 1275 ALA ALA F . n F 2 19 VAL 19 1276 1276 VAL VAL F . n F 2 20 GLU 20 1277 1277 GLU GLU F . n F 2 21 CYS 21 1278 1278 CYS CYS F . n F 2 22 LEU 22 1279 1279 LEU LEU F . n F 2 23 GLU 23 1280 1280 GLU GLU F . n F 2 24 ASN 24 1281 1281 ASN ASN F . n F 2 25 LEU 25 1282 1282 LEU LEU F . n F 2 26 VAL 26 1283 1283 VAL VAL F . n F 2 27 VAL 27 1284 1284 VAL VAL F . n F 2 28 GLY 28 1285 1285 GLY GLY F . n F 2 29 PRO 29 1286 1286 PRO PRO F . n F 2 30 VAL 30 1287 1287 VAL VAL F . n F 2 31 CYS 31 1288 1288 CYS CYS F . n F 2 32 PRO 32 1289 1289 PRO PRO F . n F 2 33 ALA 33 1290 1290 ALA ALA F . n F 2 34 ALA 34 1291 1291 ALA ALA F . n F 2 35 VAL 35 1292 1292 VAL VAL F . n F 2 36 VAL 36 1293 1293 VAL VAL F . n F 2 37 ALA 37 1294 1294 ALA ALA F . n F 2 38 PRO 38 1295 1295 PRO PRO F . n F 2 39 ALA 39 1296 1296 ALA ALA F . n F 2 40 VAL 40 1297 1297 VAL VAL F . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code G 3 NAG 1 501 501 NAG NAG A . H 4 A2G 1 502 502 A2G A2G A . I 5 SO4 1 503 503 SO4 SO4 A . J 5 SO4 1 504 504 SO4 SO4 A . K 3 NAG 1 501 501 NAG NAG C . L 5 SO4 1 502 502 SO4 SO4 C . M 5 SO4 1 503 503 SO4 SO4 C . N 3 NAG 1 501 501 NAG NAG E . O 5 SO4 1 502 502 SO4 SO4 E . P 6 HOH 1 601 601 HOH HOH A . P 6 HOH 2 602 602 HOH HOH A . P 6 HOH 3 603 603 HOH HOH A . P 6 HOH 4 604 604 HOH HOH A . P 6 HOH 5 605 605 HOH HOH A . P 6 HOH 6 606 606 HOH HOH A . P 6 HOH 7 607 607 HOH HOH A . P 6 HOH 8 608 608 HOH HOH A . P 6 HOH 9 609 609 HOH HOH A . P 6 HOH 10 610 610 HOH HOH A . P 6 HOH 11 611 611 HOH HOH A . P 6 HOH 12 612 612 HOH HOH A . P 6 HOH 13 613 613 HOH HOH A . P 6 HOH 14 614 614 HOH HOH A . P 6 HOH 15 615 615 HOH HOH A . P 6 HOH 16 616 616 HOH HOH A . P 6 HOH 17 617 617 HOH HOH A . P 6 HOH 18 618 618 HOH HOH A . P 6 HOH 19 619 619 HOH HOH A . P 6 HOH 20 620 620 HOH HOH A . P 6 HOH 21 621 621 HOH HOH A . P 6 HOH 22 622 622 HOH HOH A . P 6 HOH 23 623 623 HOH HOH A . P 6 HOH 24 624 624 HOH HOH A . P 6 HOH 25 625 625 HOH HOH A . P 6 HOH 26 626 626 HOH HOH A . P 6 HOH 27 627 627 HOH HOH A . P 6 HOH 28 628 628 HOH HOH A . P 6 HOH 29 629 629 HOH HOH A . P 6 HOH 30 630 630 HOH HOH A . P 6 HOH 31 631 631 HOH HOH A . P 6 HOH 32 632 632 HOH HOH A . P 6 HOH 33 633 633 HOH HOH A . P 6 HOH 34 634 634 HOH HOH A . P 6 HOH 35 635 635 HOH HOH A . P 6 HOH 36 636 636 HOH HOH A . P 6 HOH 37 637 637 HOH HOH A . P 6 HOH 38 638 638 HOH HOH A . P 6 HOH 39 639 639 HOH HOH A . P 6 HOH 40 640 640 HOH HOH A . P 6 HOH 41 641 641 HOH HOH A . P 6 HOH 42 642 642 HOH HOH A . P 6 HOH 43 643 643 HOH HOH A . P 6 HOH 44 644 644 HOH HOH A . P 6 HOH 45 645 645 HOH HOH A . P 6 HOH 46 646 646 HOH HOH A . P 6 HOH 47 647 647 HOH HOH A . P 6 HOH 48 648 648 HOH HOH A . P 6 HOH 49 649 649 HOH HOH A . P 6 HOH 50 650 650 HOH HOH A . P 6 HOH 51 651 651 HOH HOH A . P 6 HOH 52 652 652 HOH HOH A . P 6 HOH 53 653 653 HOH HOH A . P 6 HOH 54 654 654 HOH HOH A . P 6 HOH 55 655 655 HOH HOH A . P 6 HOH 56 656 656 HOH HOH A . P 6 HOH 57 657 657 HOH HOH A . P 6 HOH 58 658 658 HOH HOH A . P 6 HOH 59 659 659 HOH HOH A . P 6 HOH 60 660 660 HOH HOH A . P 6 HOH 61 661 661 HOH HOH A . P 6 HOH 62 662 662 HOH HOH A . P 6 HOH 63 663 663 HOH HOH A . P 6 HOH 64 664 664 HOH HOH A . P 6 HOH 65 665 665 HOH HOH A . P 6 HOH 66 666 666 HOH HOH A . P 6 HOH 67 667 667 HOH HOH A . P 6 HOH 68 668 668 HOH HOH A . P 6 HOH 69 669 669 HOH HOH A . P 6 HOH 70 670 670 HOH HOH A . P 6 HOH 71 671 671 HOH HOH A . P 6 HOH 72 672 672 HOH HOH A . P 6 HOH 73 673 673 HOH HOH A . P 6 HOH 74 674 674 HOH HOH A . P 6 HOH 75 675 675 HOH HOH A . P 6 HOH 76 676 676 HOH HOH A . P 6 HOH 77 677 677 HOH HOH A . P 6 HOH 78 678 678 HOH HOH A . P 6 HOH 79 679 679 HOH HOH A . P 6 HOH 80 680 680 HOH HOH A . P 6 HOH 81 681 681 HOH HOH A . P 6 HOH 82 682 682 HOH HOH A . P 6 HOH 83 683 683 HOH HOH A . P 6 HOH 84 684 684 HOH HOH A . P 6 HOH 85 685 685 HOH HOH A . P 6 HOH 86 686 686 HOH HOH A . P 6 HOH 87 687 687 HOH HOH A . P 6 HOH 88 688 688 HOH HOH A . P 6 HOH 89 689 689 HOH HOH A . P 6 HOH 90 690 690 HOH HOH A . P 6 HOH 91 691 691 HOH HOH A . P 6 HOH 92 692 692 HOH HOH A . P 6 HOH 93 693 693 HOH HOH A . P 6 HOH 94 694 694 HOH HOH A . P 6 HOH 95 695 695 HOH HOH A . P 6 HOH 96 696 696 HOH HOH A . P 6 HOH 97 697 697 HOH HOH A . P 6 HOH 98 698 698 HOH HOH A . P 6 HOH 99 699 699 HOH HOH A . P 6 HOH 100 700 700 HOH HOH A . P 6 HOH 101 701 701 HOH HOH A . P 6 HOH 102 702 702 HOH HOH A . P 6 HOH 103 703 703 HOH HOH A . P 6 HOH 104 704 704 HOH HOH A . P 6 HOH 105 705 705 HOH HOH A . P 6 HOH 106 706 706 HOH HOH A . P 6 HOH 107 707 707 HOH HOH A . P 6 HOH 108 708 708 HOH HOH A . P 6 HOH 109 709 709 HOH HOH A . P 6 HOH 110 710 710 HOH HOH A . P 6 HOH 111 711 711 HOH HOH A . P 6 HOH 112 712 712 HOH HOH A . P 6 HOH 113 713 713 HOH HOH A . P 6 HOH 114 714 714 HOH HOH A . P 6 HOH 115 715 715 HOH HOH A . P 6 HOH 116 716 716 HOH HOH A . P 6 HOH 117 717 717 HOH HOH A . P 6 HOH 118 718 718 HOH HOH A . P 6 HOH 119 719 719 HOH HOH A . P 6 HOH 120 720 720 HOH HOH A . P 6 HOH 121 721 721 HOH HOH A . P 6 HOH 122 722 722 HOH HOH A . P 6 HOH 123 723 723 HOH HOH A . P 6 HOH 124 724 724 HOH HOH A . P 6 HOH 125 725 725 HOH HOH A . P 6 HOH 126 726 726 HOH HOH A . P 6 HOH 127 727 727 HOH HOH A . P 6 HOH 128 728 728 HOH HOH A . P 6 HOH 129 729 729 HOH HOH A . P 6 HOH 130 730 730 HOH HOH A . P 6 HOH 131 731 731 HOH HOH A . P 6 HOH 132 732 732 HOH HOH A . P 6 HOH 133 733 733 HOH HOH A . P 6 HOH 134 734 734 HOH HOH A . P 6 HOH 135 735 735 HOH HOH A . P 6 HOH 136 736 736 HOH HOH A . P 6 HOH 137 737 737 HOH HOH A . P 6 HOH 138 738 738 HOH HOH A . P 6 HOH 139 739 739 HOH HOH A . P 6 HOH 140 740 740 HOH HOH A . P 6 HOH 141 741 741 HOH HOH A . P 6 HOH 142 742 742 HOH HOH A . P 6 HOH 143 743 743 HOH HOH A . P 6 HOH 144 744 744 HOH HOH A . P 6 HOH 145 745 745 HOH HOH A . P 6 HOH 146 746 746 HOH HOH A . P 6 HOH 147 747 747 HOH HOH A . P 6 HOH 148 748 748 HOH HOH A . P 6 HOH 149 749 749 HOH HOH A . P 6 HOH 150 750 750 HOH HOH A . P 6 HOH 151 751 751 HOH HOH A . P 6 HOH 152 752 752 HOH HOH A . P 6 HOH 153 753 753 HOH HOH A . P 6 HOH 154 754 754 HOH HOH A . P 6 HOH 155 755 755 HOH HOH A . P 6 HOH 156 756 756 HOH HOH A . P 6 HOH 157 757 757 HOH HOH A . P 6 HOH 158 758 758 HOH HOH A . P 6 HOH 159 759 759 HOH HOH A . P 6 HOH 160 760 760 HOH HOH A . P 6 HOH 161 761 761 HOH HOH A . P 6 HOH 162 762 762 HOH HOH A . P 6 HOH 163 763 763 HOH HOH A . P 6 HOH 164 764 764 HOH HOH A . P 6 HOH 165 765 765 HOH HOH A . Q 6 HOH 1 601 601 HOH HOH C . Q 6 HOH 2 602 602 HOH HOH C . Q 6 HOH 3 603 603 HOH HOH C . Q 6 HOH 4 604 604 HOH HOH C . Q 6 HOH 5 605 605 HOH HOH C . Q 6 HOH 6 606 606 HOH HOH C . Q 6 HOH 7 607 607 HOH HOH C . Q 6 HOH 8 608 608 HOH HOH C . Q 6 HOH 9 609 609 HOH HOH C . Q 6 HOH 10 610 610 HOH HOH C . Q 6 HOH 11 611 611 HOH HOH C . Q 6 HOH 12 612 612 HOH HOH C . Q 6 HOH 13 613 613 HOH HOH C . Q 6 HOH 14 614 614 HOH HOH C . Q 6 HOH 15 615 615 HOH HOH C . Q 6 HOH 16 616 616 HOH HOH C . Q 6 HOH 17 617 617 HOH HOH C . Q 6 HOH 18 618 618 HOH HOH C . Q 6 HOH 19 619 619 HOH HOH C . Q 6 HOH 20 620 620 HOH HOH C . Q 6 HOH 21 621 621 HOH HOH C . Q 6 HOH 22 622 622 HOH HOH C . Q 6 HOH 23 623 623 HOH HOH C . Q 6 HOH 24 624 624 HOH HOH C . Q 6 HOH 25 625 625 HOH HOH C . Q 6 HOH 26 626 626 HOH HOH C . Q 6 HOH 27 627 627 HOH HOH C . Q 6 HOH 28 628 628 HOH HOH C . Q 6 HOH 29 629 629 HOH HOH C . Q 6 HOH 30 630 630 HOH HOH C . Q 6 HOH 31 631 631 HOH HOH C . Q 6 HOH 32 632 632 HOH HOH C . Q 6 HOH 33 633 633 HOH HOH C . Q 6 HOH 34 634 634 HOH HOH C . Q 6 HOH 35 635 635 HOH HOH C . Q 6 HOH 36 636 636 HOH HOH C . Q 6 HOH 37 637 637 HOH HOH C . Q 6 HOH 38 638 638 HOH HOH C . Q 6 HOH 39 639 639 HOH HOH C . Q 6 HOH 40 640 640 HOH HOH C . Q 6 HOH 41 641 641 HOH HOH C . Q 6 HOH 42 642 642 HOH HOH C . Q 6 HOH 43 643 643 HOH HOH C . Q 6 HOH 44 644 644 HOH HOH C . Q 6 HOH 45 645 645 HOH HOH C . Q 6 HOH 46 646 646 HOH HOH C . Q 6 HOH 47 647 647 HOH HOH C . Q 6 HOH 48 648 648 HOH HOH C . Q 6 HOH 49 649 649 HOH HOH C . Q 6 HOH 50 650 650 HOH HOH C . Q 6 HOH 51 651 651 HOH HOH C . Q 6 HOH 52 652 652 HOH HOH C . Q 6 HOH 53 653 653 HOH HOH C . Q 6 HOH 54 654 654 HOH HOH C . Q 6 HOH 55 655 655 HOH HOH C . Q 6 HOH 56 656 656 HOH HOH C . Q 6 HOH 57 657 657 HOH HOH C . Q 6 HOH 58 658 658 HOH HOH C . Q 6 HOH 59 659 659 HOH HOH C . Q 6 HOH 60 660 660 HOH HOH C . Q 6 HOH 61 661 661 HOH HOH C . Q 6 HOH 62 662 662 HOH HOH C . Q 6 HOH 63 663 663 HOH HOH C . Q 6 HOH 64 664 664 HOH HOH C . Q 6 HOH 65 665 665 HOH HOH C . Q 6 HOH 66 666 666 HOH HOH C . Q 6 HOH 67 667 667 HOH HOH C . Q 6 HOH 68 668 668 HOH HOH C . Q 6 HOH 69 669 669 HOH HOH C . Q 6 HOH 70 670 670 HOH HOH C . Q 6 HOH 71 671 671 HOH HOH C . Q 6 HOH 72 672 672 HOH HOH C . Q 6 HOH 73 673 673 HOH HOH C . Q 6 HOH 74 674 674 HOH HOH C . Q 6 HOH 75 675 675 HOH HOH C . Q 6 HOH 76 676 676 HOH HOH C . Q 6 HOH 77 677 677 HOH HOH C . Q 6 HOH 78 678 678 HOH HOH C . Q 6 HOH 79 679 679 HOH HOH C . Q 6 HOH 80 680 680 HOH HOH C . Q 6 HOH 81 681 681 HOH HOH C . Q 6 HOH 82 682 682 HOH HOH C . Q 6 HOH 83 683 683 HOH HOH C . Q 6 HOH 84 684 684 HOH HOH C . Q 6 HOH 85 685 685 HOH HOH C . Q 6 HOH 86 686 686 HOH HOH C . Q 6 HOH 87 687 687 HOH HOH C . Q 6 HOH 88 688 688 HOH HOH C . Q 6 HOH 89 689 689 HOH HOH C . Q 6 HOH 90 690 690 HOH HOH C . Q 6 HOH 91 691 691 HOH HOH C . Q 6 HOH 92 692 692 HOH HOH C . Q 6 HOH 93 693 693 HOH HOH C . Q 6 HOH 94 694 694 HOH HOH C . Q 6 HOH 95 695 695 HOH HOH C . Q 6 HOH 96 696 696 HOH HOH C . Q 6 HOH 97 697 697 HOH HOH C . Q 6 HOH 98 698 698 HOH HOH C . Q 6 HOH 99 699 699 HOH HOH C . Q 6 HOH 100 700 700 HOH HOH C . Q 6 HOH 101 701 701 HOH HOH C . Q 6 HOH 102 702 702 HOH HOH C . Q 6 HOH 103 703 703 HOH HOH C . Q 6 HOH 104 704 704 HOH HOH C . Q 6 HOH 105 705 705 HOH HOH C . Q 6 HOH 106 706 706 HOH HOH C . Q 6 HOH 107 707 707 HOH HOH C . Q 6 HOH 108 708 708 HOH HOH C . Q 6 HOH 109 709 709 HOH HOH C . Q 6 HOH 110 710 710 HOH HOH C . Q 6 HOH 111 711 711 HOH HOH C . Q 6 HOH 112 712 712 HOH HOH C . Q 6 HOH 113 713 713 HOH HOH C . Q 6 HOH 114 714 714 HOH HOH C . Q 6 HOH 115 715 715 HOH HOH C . Q 6 HOH 116 716 716 HOH HOH C . Q 6 HOH 117 717 717 HOH HOH C . Q 6 HOH 118 718 718 HOH HOH C . Q 6 HOH 119 719 719 HOH HOH C . Q 6 HOH 120 720 720 HOH HOH C . Q 6 HOH 121 721 721 HOH HOH C . Q 6 HOH 122 722 722 HOH HOH C . Q 6 HOH 123 723 723 HOH HOH C . Q 6 HOH 124 724 724 HOH HOH C . Q 6 HOH 125 725 725 HOH HOH C . Q 6 HOH 126 726 726 HOH HOH C . Q 6 HOH 127 727 727 HOH HOH C . Q 6 HOH 128 728 728 HOH HOH C . Q 6 HOH 129 729 729 HOH HOH C . Q 6 HOH 130 730 730 HOH HOH C . Q 6 HOH 131 731 731 HOH HOH C . Q 6 HOH 132 732 732 HOH HOH C . Q 6 HOH 133 733 733 HOH HOH C . R 6 HOH 1 601 601 HOH HOH E . R 6 HOH 2 602 602 HOH HOH E . R 6 HOH 3 603 603 HOH HOH E . R 6 HOH 4 604 604 HOH HOH E . R 6 HOH 5 605 605 HOH HOH E . R 6 HOH 6 606 606 HOH HOH E . R 6 HOH 7 607 607 HOH HOH E . R 6 HOH 8 608 608 HOH HOH E . R 6 HOH 9 609 609 HOH HOH E . R 6 HOH 10 610 610 HOH HOH E . R 6 HOH 11 611 611 HOH HOH E . R 6 HOH 12 612 612 HOH HOH E . R 6 HOH 13 613 613 HOH HOH E . R 6 HOH 14 614 614 HOH HOH E . R 6 HOH 15 615 615 HOH HOH E . R 6 HOH 16 616 616 HOH HOH E . R 6 HOH 17 617 617 HOH HOH E . R 6 HOH 18 618 618 HOH HOH E . R 6 HOH 19 619 619 HOH HOH E . R 6 HOH 20 620 620 HOH HOH E . R 6 HOH 21 621 621 HOH HOH E . R 6 HOH 22 622 622 HOH HOH E . R 6 HOH 23 623 623 HOH HOH E . R 6 HOH 24 624 624 HOH HOH E . R 6 HOH 25 625 625 HOH HOH E . R 6 HOH 26 626 626 HOH HOH E . R 6 HOH 27 627 627 HOH HOH E . R 6 HOH 28 628 628 HOH HOH E . R 6 HOH 29 629 629 HOH HOH E . R 6 HOH 30 630 630 HOH HOH E . R 6 HOH 31 631 631 HOH HOH E . R 6 HOH 32 632 632 HOH HOH E . R 6 HOH 33 633 633 HOH HOH E . R 6 HOH 34 634 634 HOH HOH E . R 6 HOH 35 635 635 HOH HOH E . R 6 HOH 36 636 636 HOH HOH E . R 6 HOH 37 637 637 HOH HOH E . R 6 HOH 38 638 638 HOH HOH E . R 6 HOH 39 639 639 HOH HOH E . R 6 HOH 40 640 640 HOH HOH E . R 6 HOH 41 641 641 HOH HOH E . R 6 HOH 42 642 642 HOH HOH E . R 6 HOH 43 643 643 HOH HOH E . R 6 HOH 44 644 644 HOH HOH E . R 6 HOH 45 645 645 HOH HOH E . R 6 HOH 46 646 646 HOH HOH E . R 6 HOH 47 647 647 HOH HOH E . R 6 HOH 48 648 648 HOH HOH E . R 6 HOH 49 649 649 HOH HOH E . R 6 HOH 50 650 650 HOH HOH E . R 6 HOH 51 651 651 HOH HOH E . R 6 HOH 52 652 652 HOH HOH E . R 6 HOH 53 653 653 HOH HOH E . R 6 HOH 54 654 654 HOH HOH E . R 6 HOH 55 655 655 HOH HOH E . R 6 HOH 56 656 656 HOH HOH E . R 6 HOH 57 657 657 HOH HOH E . R 6 HOH 58 658 658 HOH HOH E . R 6 HOH 59 659 659 HOH HOH E . R 6 HOH 60 660 660 HOH HOH E . R 6 HOH 61 661 661 HOH HOH E . R 6 HOH 62 662 662 HOH HOH E . R 6 HOH 63 663 663 HOH HOH E . R 6 HOH 64 664 664 HOH HOH E . R 6 HOH 65 665 665 HOH HOH E . R 6 HOH 66 666 666 HOH HOH E . R 6 HOH 67 667 667 HOH HOH E . R 6 HOH 68 668 668 HOH HOH E . R 6 HOH 69 669 669 HOH HOH E . R 6 HOH 70 670 670 HOH HOH E . R 6 HOH 71 671 671 HOH HOH E . R 6 HOH 72 672 672 HOH HOH E . R 6 HOH 73 673 673 HOH HOH E . R 6 HOH 74 674 674 HOH HOH E . R 6 HOH 75 675 675 HOH HOH E . R 6 HOH 76 676 676 HOH HOH E . R 6 HOH 77 677 677 HOH HOH E . R 6 HOH 78 678 678 HOH HOH E . R 6 HOH 79 679 679 HOH HOH E . R 6 HOH 80 680 680 HOH HOH E . R 6 HOH 81 681 681 HOH HOH E . R 6 HOH 82 682 682 HOH HOH E . R 6 HOH 83 683 683 HOH HOH E . R 6 HOH 84 684 684 HOH HOH E . R 6 HOH 85 685 685 HOH HOH E . R 6 HOH 86 686 686 HOH HOH E . R 6 HOH 87 687 687 HOH HOH E . R 6 HOH 88 688 688 HOH HOH E . R 6 HOH 89 689 689 HOH HOH E . R 6 HOH 90 690 690 HOH HOH E . R 6 HOH 91 691 691 HOH HOH E . R 6 HOH 92 692 692 HOH HOH E . R 6 HOH 93 693 693 HOH HOH E . R 6 HOH 94 694 694 HOH HOH E . R 6 HOH 95 695 695 HOH HOH E . R 6 HOH 96 696 696 HOH HOH E . R 6 HOH 97 697 697 HOH HOH E . R 6 HOH 98 698 698 HOH HOH E . R 6 HOH 99 699 699 HOH HOH E . R 6 HOH 100 700 700 HOH HOH E . R 6 HOH 101 701 701 HOH HOH E . R 6 HOH 102 702 702 HOH HOH E . R 6 HOH 103 703 703 HOH HOH E . R 6 HOH 104 704 704 HOH HOH E . R 6 HOH 105 705 705 HOH HOH E . R 6 HOH 106 706 706 HOH HOH E . R 6 HOH 107 707 707 HOH HOH E . R 6 HOH 108 708 708 HOH HOH E . R 6 HOH 109 709 709 HOH HOH E . R 6 HOH 110 710 710 HOH HOH E . R 6 HOH 111 711 711 HOH HOH E . R 6 HOH 112 712 712 HOH HOH E . R 6 HOH 113 713 713 HOH HOH E . R 6 HOH 114 714 714 HOH HOH E . R 6 HOH 115 715 715 HOH HOH E . R 6 HOH 116 716 716 HOH HOH E . R 6 HOH 117 717 717 HOH HOH E . R 6 HOH 118 718 718 HOH HOH E . R 6 HOH 119 719 719 HOH HOH E . R 6 HOH 120 720 720 HOH HOH E . R 6 HOH 121 721 721 HOH HOH E . R 6 HOH 122 722 722 HOH HOH E . R 6 HOH 123 723 723 HOH HOH E . R 6 HOH 124 724 724 HOH HOH E . R 6 HOH 125 725 725 HOH HOH E . R 6 HOH 126 726 726 HOH HOH E . R 6 HOH 127 727 727 HOH HOH E . R 6 HOH 128 728 728 HOH HOH E . R 6 HOH 129 729 729 HOH HOH E . R 6 HOH 130 730 730 HOH HOH E . R 6 HOH 131 731 731 HOH HOH E . R 6 HOH 132 732 732 HOH HOH E . R 6 HOH 133 733 733 HOH HOH E . R 6 HOH 134 734 734 HOH HOH E . R 6 HOH 135 735 735 HOH HOH E . R 6 HOH 136 736 736 HOH HOH E . R 6 HOH 137 737 737 HOH HOH E . R 6 HOH 138 738 738 HOH HOH E . R 6 HOH 139 739 739 HOH HOH E . R 6 HOH 140 740 740 HOH HOH E . R 6 HOH 141 741 741 HOH HOH E . R 6 HOH 142 742 742 HOH HOH E . R 6 HOH 143 743 743 HOH HOH E . R 6 HOH 144 744 744 HOH HOH E . R 6 HOH 145 745 745 HOH HOH E . R 6 HOH 146 746 746 HOH HOH E . R 6 HOH 147 747 747 HOH HOH E . R 6 HOH 148 748 748 HOH HOH E . R 6 HOH 149 749 749 HOH HOH E . R 6 HOH 150 750 750 HOH HOH E . R 6 HOH 151 751 751 HOH HOH E . R 6 HOH 152 752 752 HOH HOH E . R 6 HOH 153 753 753 HOH HOH E . S 6 HOH 1 1301 1301 HOH HOH B . S 6 HOH 2 1302 1302 HOH HOH B . S 6 HOH 3 1303 1303 HOH HOH B . S 6 HOH 4 1304 1304 HOH HOH B . S 6 HOH 5 1305 1305 HOH HOH B . S 6 HOH 6 1306 1306 HOH HOH B . S 6 HOH 7 1307 1307 HOH HOH B . S 6 HOH 8 1308 1308 HOH HOH B . S 6 HOH 9 1309 1309 HOH HOH B . S 6 HOH 10 1310 1310 HOH HOH B . S 6 HOH 11 1311 1311 HOH HOH B . T 6 HOH 1 1301 1301 HOH HOH D . T 6 HOH 2 1302 1302 HOH HOH D . T 6 HOH 3 1303 1303 HOH HOH D . T 6 HOH 4 1304 1304 HOH HOH D . T 6 HOH 5 1305 1305 HOH HOH D . T 6 HOH 6 1306 1306 HOH HOH D . T 6 HOH 7 1307 1307 HOH HOH D . T 6 HOH 8 1308 1308 HOH HOH D . T 6 HOH 9 1309 1309 HOH HOH D . T 6 HOH 10 1310 1310 HOH HOH D . T 6 HOH 11 1311 1311 HOH HOH D . T 6 HOH 12 1312 1312 HOH HOH D . U 6 HOH 1 1301 1301 HOH HOH F . U 6 HOH 2 1302 1302 HOH HOH F . U 6 HOH 3 1303 1303 HOH HOH F . U 6 HOH 4 1304 1304 HOH HOH F . U 6 HOH 5 1305 1305 HOH HOH F . U 6 HOH 6 1306 1306 HOH HOH F . U 6 HOH 7 1307 1307 HOH HOH F . U 6 HOH 8 1308 1308 HOH HOH F . U 6 HOH 9 1309 1309 HOH HOH F . U 6 HOH 10 1310 1310 HOH HOH F . U 6 HOH 11 1311 1311 HOH HOH F . U 6 HOH 12 1312 1312 HOH HOH F . U 6 HOH 13 1313 1313 HOH HOH F . # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA dimeric 2 2 author_and_software_defined_assembly PISA dimeric 2 3 author_and_software_defined_assembly PISA dimeric 2 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,D,G,H,I,J,P,S 2 1 B,E,K,L,M,Q,T 3 1 C,F,N,O,R,U # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 4300 ? 1 MORE -39 ? 1 'SSA (A^2)' 19480 ? 2 'ABSA (A^2)' 3880 ? 2 MORE -32 ? 2 'SSA (A^2)' 19510 ? 3 'ABSA (A^2)' 3810 ? 3 MORE -33 ? 3 'SSA (A^2)' 19300 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # _pdbx_struct_special_symmetry.id 1 _pdbx_struct_special_symmetry.PDB_model_num 1 _pdbx_struct_special_symmetry.auth_asym_id C _pdbx_struct_special_symmetry.auth_comp_id SO4 _pdbx_struct_special_symmetry.auth_seq_id 503 _pdbx_struct_special_symmetry.PDB_ins_code ? _pdbx_struct_special_symmetry.label_asym_id M _pdbx_struct_special_symmetry.label_comp_id SO4 _pdbx_struct_special_symmetry.label_seq_id . # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2015-05-20 2 'Structure model' 1 1 2017-09-20 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Author supporting evidence' 2 2 'Structure model' 'Derived calculations' 3 2 'Structure model' 'Source and taxonomy' # loop_ _pdbx_audit_revision_category.ordinal _pdbx_audit_revision_category.revision_ordinal _pdbx_audit_revision_category.data_content_type _pdbx_audit_revision_category.category 1 2 'Structure model' entity_src_gen 2 2 'Structure model' pdbx_audit_support 3 2 'Structure model' pdbx_struct_assembly 4 2 'Structure model' pdbx_struct_assembly_gen 5 2 'Structure model' pdbx_struct_assembly_prop 6 2 'Structure model' pdbx_struct_oper_list # loop_ _pdbx_audit_revision_item.ordinal _pdbx_audit_revision_item.revision_ordinal _pdbx_audit_revision_item.data_content_type _pdbx_audit_revision_item.item 1 2 'Structure model' '_entity_src_gen.pdbx_alt_source_flag' 2 2 'Structure model' '_pdbx_audit_support.funding_organization' 3 2 'Structure model' '_pdbx_struct_assembly.oligomeric_details' 4 2 'Structure model' '_pdbx_struct_assembly_gen.asym_id_list' 5 2 'Structure model' '_pdbx_struct_assembly_prop.type' 6 2 'Structure model' '_pdbx_struct_assembly_prop.value' 7 2 'Structure model' '_pdbx_struct_oper_list.symmetry_operation' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? . 1 ? 'data collection' ? ? ? ? ? ? ? ? ? ? ? Blu-Ice ? ? ? . 2 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? MOSFLM ? ? ? . 3 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? SCALA ? ? ? . 4 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? . 5 ? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot ? ? ? . 6 ? 'data extraction' ? ? ? ? ? ? ? ? ? ? ? PDB_EXTRACT ? ? ? 3.15 7 # _pdbx_entry_details.compound_details ? _pdbx_entry_details.entry_id 4YIZ _pdbx_entry_details.nonpolymer_details ? _pdbx_entry_details.sequence_details ;The authors state that the twenty flexible residues of the DII loop (HTYPLTSQASWNDWWPLHQS) were replaced with a seven residue Gly-Ser linker (GSGSGSG). ; _pdbx_entry_details.source_details ? # _pdbx_validate_close_contact.id 1 _pdbx_validate_close_contact.PDB_model_num 1 _pdbx_validate_close_contact.auth_atom_id_1 O _pdbx_validate_close_contact.auth_asym_id_1 A _pdbx_validate_close_contact.auth_comp_id_1 HOH _pdbx_validate_close_contact.auth_seq_id_1 747 _pdbx_validate_close_contact.PDB_ins_code_1 ? _pdbx_validate_close_contact.label_alt_id_1 ? _pdbx_validate_close_contact.auth_atom_id_2 O _pdbx_validate_close_contact.auth_asym_id_2 A _pdbx_validate_close_contact.auth_comp_id_2 HOH _pdbx_validate_close_contact.auth_seq_id_2 756 _pdbx_validate_close_contact.PDB_ins_code_2 ? _pdbx_validate_close_contact.label_alt_id_2 ? _pdbx_validate_close_contact.dist 2.14 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 LEU A 99 ? ? -142.21 53.87 2 1 ALA A 114 ? ? -141.36 -4.13 3 1 ASP A 130 ? ? -93.66 54.06 4 1 ASP A 397 ? ? -161.42 104.81 5 1 LEU C 99 ? ? -146.85 51.40 6 1 LYS C 200 ? ? -92.54 30.10 7 1 ASP C 397 ? ? -162.34 104.14 8 1 ALA E 74 ? ? -65.79 -76.67 9 1 LEU E 99 ? ? -142.82 51.38 10 1 LYS E 301 ? ? 39.26 49.09 11 1 ASP E 397 ? ? -167.02 107.07 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLY 59 ? A GLY 1 2 1 Y 1 A SER 60 ? A SER 2 3 1 Y 1 A ALA 61 ? A ALA 3 4 1 Y 1 A MET 62 ? A MET 4 5 1 Y 1 A GLY 63 ? A GLY 5 6 1 Y 1 A SER 64 ? A SER 6 7 1 Y 1 A ALA 65 ? A ALA 7 8 1 Y 1 A SER 66 ? A SER 8 9 1 Y 1 A THR 67 ? A THR 9 10 1 Y 1 A GLY 353 ? A GLY 282 11 1 Y 1 A SER 354 ? A SER 283 12 1 Y 1 A GLY 355 ? A GLY 284 13 1 Y 1 A SER 356 ? A SER 285 14 1 Y 1 A GLY 357 ? A GLY 286 15 1 Y 1 A SER 358 ? A SER 287 16 1 Y 1 A GLY 359 ? A GLY 288 17 1 Y 1 A GLY 480 ? A GLY 409 18 1 Y 1 A SER 481 ? A SER 410 19 1 Y 1 A ASN 482 ? A ASN 411 20 1 Y 1 A THR 483 ? A THR 412 21 1 Y 1 A ALA 484 ? A ALA 413 22 1 Y 1 A ALA 485 ? A ALA 414 23 1 Y 1 A ALA 486 ? A ALA 415 24 1 Y 1 A LEU 487 ? A LEU 416 25 1 Y 1 A VAL 488 ? A VAL 417 26 1 Y 1 A PRO 489 ? A PRO 418 27 1 Y 1 A ARG 490 ? A ARG 419 28 1 Y 1 C GLY 59 ? B GLY 1 29 1 Y 1 C SER 60 ? B SER 2 30 1 Y 1 C ALA 61 ? B ALA 3 31 1 Y 1 C MET 62 ? B MET 4 32 1 Y 1 C GLY 63 ? B GLY 5 33 1 Y 1 C SER 64 ? B SER 6 34 1 Y 1 C ALA 65 ? B ALA 7 35 1 Y 1 C SER 66 ? B SER 8 36 1 Y 1 C THR 67 ? B THR 9 37 1 Y 1 C GLY 353 ? B GLY 282 38 1 Y 1 C SER 354 ? B SER 283 39 1 Y 1 C GLY 355 ? B GLY 284 40 1 Y 1 C SER 356 ? B SER 285 41 1 Y 1 C GLY 357 ? B GLY 286 42 1 Y 1 C SER 358 ? B SER 287 43 1 Y 1 C GLY 359 ? B GLY 288 44 1 Y 1 C GLY 480 ? B GLY 409 45 1 Y 1 C SER 481 ? B SER 410 46 1 Y 1 C ASN 482 ? B ASN 411 47 1 Y 1 C THR 483 ? B THR 412 48 1 Y 1 C ALA 484 ? B ALA 413 49 1 Y 1 C ALA 485 ? B ALA 414 50 1 Y 1 C ALA 486 ? B ALA 415 51 1 Y 1 C LEU 487 ? B LEU 416 52 1 Y 1 C VAL 488 ? B VAL 417 53 1 Y 1 C PRO 489 ? B PRO 418 54 1 Y 1 C ARG 490 ? B ARG 419 55 1 Y 1 E GLY 59 ? C GLY 1 56 1 Y 1 E SER 60 ? C SER 2 57 1 Y 1 E ALA 61 ? C ALA 3 58 1 Y 1 E MET 62 ? C MET 4 59 1 Y 1 E GLY 63 ? C GLY 5 60 1 Y 1 E SER 64 ? C SER 6 61 1 Y 1 E ALA 65 ? C ALA 7 62 1 Y 1 E SER 66 ? C SER 8 63 1 Y 1 E THR 67 ? C THR 9 64 1 Y 1 E GLY 353 ? C GLY 282 65 1 Y 1 E SER 354 ? C SER 283 66 1 Y 1 E GLY 355 ? C GLY 284 67 1 Y 1 E SER 356 ? C SER 285 68 1 Y 1 E GLY 357 ? C GLY 286 69 1 Y 1 E SER 358 ? C SER 287 70 1 Y 1 E GLY 359 ? C GLY 288 71 1 Y 1 E PRO 422 ? C PRO 351 72 1 Y 1 E SER 423 ? C SER 352 73 1 Y 1 E VAL 424 ? C VAL 353 74 1 Y 1 E THR 425 ? C THR 354 75 1 Y 1 E PRO 426 ? C PRO 355 76 1 Y 1 E SER 481 ? C SER 410 77 1 Y 1 E ASN 482 ? C ASN 411 78 1 Y 1 E THR 483 ? C THR 412 79 1 Y 1 E ALA 484 ? C ALA 413 80 1 Y 1 E ALA 485 ? C ALA 414 81 1 Y 1 E ALA 486 ? C ALA 415 82 1 Y 1 E LEU 487 ? C LEU 416 83 1 Y 1 E VAL 488 ? C VAL 417 84 1 Y 1 E PRO 489 ? C PRO 418 85 1 Y 1 E ARG 490 ? C ARG 419 86 1 Y 1 B GLY 1258 ? D GLY 1 87 1 Y 1 D GLY 1258 ? E GLY 1 88 1 Y 1 F GLY 1258 ? F GLY 1 # _pdbx_audit_support.funding_organization 'Canadian Institutes of Health Research' _pdbx_audit_support.country Canada _pdbx_audit_support.grant_number MOP82915 _pdbx_audit_support.ordinal 1 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 3 N-ACETYL-D-GLUCOSAMINE NAG 4 N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE A2G 5 'SULFATE ION' SO4 6 water HOH #