data_4YH7 # _entry.id 4YH7 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4YH7 WWPDB D_1000207456 # _pdbx_database_related.db_name PDB _pdbx_database_related.details . _pdbx_database_related.db_id 4YH6 _pdbx_database_related.content_type unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 4YH7 _pdbx_database_status.recvd_initial_deposition_date 2015-02-27 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBJ _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Yamagata, A.' 1 'Fukai, S.' 2 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country UK _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'Nat Commun' _citation.journal_id_ASTM ? _citation.journal_id_CSD ? _citation.journal_id_ISSN 2041-1723 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 6 _citation.language ? _citation.page_first 6926 _citation.page_last 6926 _citation.title 'Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.' _citation.year 2015 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1038/ncomms7926 _citation.pdbx_database_id_PubMed 25908590 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Yamagata, A.' 1 primary 'Yoshida, T.' 2 primary 'Sato, Y.' 3 primary 'Goto-Ito, S.' 4 primary 'Uemura, T.' 5 primary 'Maeda, A.' 6 primary 'Shiroshima, T.' 7 primary 'Iwasawa-Okamoto, S.' 8 primary 'Mori, H.' 9 primary 'Mishina, M.' 10 primary 'Fukai, S.' 11 # _cell.entry_id 4YH7 _cell.length_a 286.295 _cell.length_b 286.295 _cell.length_c 70.183 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? # _symmetry.entry_id 4YH7 _symmetry.space_group_name_H-M 'I 41' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 80 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Receptor-type tyrosine-protein phosphatase delta' 93559.461 1 3.1.3.48 ? 'UNP RESIDUES 21-854' ? 2 polymer man 'Interleukin-1 receptor accessory protein-like 1' 39816.277 1 ? ? 'UNP RESIDUES 19-352' ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 6 ? ? ? ? 4 non-polymer man BETA-D-MANNOSE 180.156 1 ? ? ? ? 5 non-polymer man ALPHA-D-MANNOSE 180.156 2 ? ? ? ? # loop_ _entity_name_com.entity_id _entity_name_com.name 1 R-PTP-delta 2 'IL1RAPL-1,X-linked interleukin-1 receptor accessory protein-like 1' # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVA SNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRS ESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAV GSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSIT LTWDSGNPEPVSYYIIQHKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSA PRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGD GPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQGEEQRITIEPGTSYRLQGLKPNSL YYFRLSARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKL IVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPDVPANENIKGYYIIIVPLKKSR GKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLA VMDHAESKMYATSPYSDPVVSMDLDPQPITDEEEKHHHHHH ; ;ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVA SNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRS ESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAV GSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSIT LTWDSGNPEPVSYYIIQHKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSA PRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGD GPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQGEEQRITIEPGTSYRLQGLKPNSL YYFRLSARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKL IVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPDVPANENIKGYYIIIVPLKKSR GKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLA VMDHAESKMYATSPYSDPVVSMDLDPQPITDEEEKHHHHHH ; A ? 2 'polypeptide(L)' no no ;AQPAARDLKVVTKRGSADGCTDWSVDIKKYQVLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAF DGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFL LPTREPEILWYKECRTKAWRPSIVFKRDTLLIKEVKEDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESK LTVQETQLGGSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGN YSCYVENGNGRRHASVLLHKRKHHHHHH ; ;AQPAARDLKVVTKRGSADGCTDWSVDIKKYQVLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAF DGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFL LPTREPEILWYKECRTKAWRPSIVFKRDTLLIKEVKEDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESK LTVQETQLGGSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGN YSCYVENGNGRRHASVLLHKRKHHHHHH ; B ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLU n 1 2 THR n 1 3 PRO n 1 4 PRO n 1 5 ARG n 1 6 PHE n 1 7 THR n 1 8 ARG n 1 9 THR n 1 10 PRO n 1 11 VAL n 1 12 ASP n 1 13 GLN n 1 14 THR n 1 15 GLY n 1 16 VAL n 1 17 SER n 1 18 GLY n 1 19 GLY n 1 20 VAL n 1 21 ALA n 1 22 SER n 1 23 PHE n 1 24 ILE n 1 25 CYS n 1 26 GLN n 1 27 ALA n 1 28 THR n 1 29 GLY n 1 30 ASP n 1 31 PRO n 1 32 ARG n 1 33 PRO n 1 34 LYS n 1 35 ILE n 1 36 VAL n 1 37 TRP n 1 38 ASN n 1 39 LYS n 1 40 LYS n 1 41 GLY n 1 42 LYS n 1 43 LYS n 1 44 VAL n 1 45 SER n 1 46 ASN n 1 47 GLN n 1 48 ARG n 1 49 PHE n 1 50 GLU n 1 51 VAL n 1 52 ILE n 1 53 GLU n 1 54 PHE n 1 55 ASP n 1 56 ASP n 1 57 GLY n 1 58 SER n 1 59 GLY n 1 60 SER n 1 61 VAL n 1 62 LEU n 1 63 ARG n 1 64 ILE n 1 65 GLN n 1 66 PRO n 1 67 LEU n 1 68 ARG n 1 69 THR n 1 70 PRO n 1 71 ARG n 1 72 ASP n 1 73 GLU n 1 74 ALA n 1 75 ILE n 1 76 TYR n 1 77 GLU n 1 78 CYS n 1 79 VAL n 1 80 ALA n 1 81 SER n 1 82 ASN n 1 83 ASN n 1 84 VAL n 1 85 GLY n 1 86 GLU n 1 87 ILE n 1 88 SER n 1 89 VAL n 1 90 SER n 1 91 THR n 1 92 ARG n 1 93 LEU n 1 94 THR n 1 95 VAL n 1 96 LEU n 1 97 ARG n 1 98 GLU n 1 99 ASP n 1 100 GLN n 1 101 ILE n 1 102 PRO n 1 103 ARG n 1 104 GLY n 1 105 PHE n 1 106 PRO n 1 107 THR n 1 108 ILE n 1 109 ASP n 1 110 MET n 1 111 GLY n 1 112 PRO n 1 113 GLN n 1 114 LEU n 1 115 LYS n 1 116 VAL n 1 117 VAL n 1 118 GLU n 1 119 ARG n 1 120 THR n 1 121 ARG n 1 122 THR n 1 123 ALA n 1 124 THR n 1 125 MET n 1 126 LEU n 1 127 CYS n 1 128 ALA n 1 129 ALA n 1 130 SER n 1 131 GLY n 1 132 ASN n 1 133 PRO n 1 134 ASP n 1 135 PRO n 1 136 GLU n 1 137 ILE n 1 138 THR n 1 139 TRP n 1 140 PHE n 1 141 LYS n 1 142 ASP n 1 143 PHE n 1 144 LEU n 1 145 PRO n 1 146 VAL n 1 147 ASP n 1 148 THR n 1 149 SER n 1 150 ASN n 1 151 ASN n 1 152 ASN n 1 153 GLY n 1 154 ARG n 1 155 ILE n 1 156 LYS n 1 157 GLN n 1 158 LEU n 1 159 ARG n 1 160 SER n 1 161 GLU n 1 162 SER n 1 163 ILE n 1 164 GLY n 1 165 GLY n 1 166 THR n 1 167 PRO n 1 168 ILE n 1 169 ARG n 1 170 GLY n 1 171 ALA n 1 172 LEU n 1 173 GLN n 1 174 ILE n 1 175 GLU n 1 176 GLN n 1 177 SER n 1 178 GLU n 1 179 GLU n 1 180 SER n 1 181 ASP n 1 182 GLN n 1 183 GLY n 1 184 LYS n 1 185 TYR n 1 186 GLU n 1 187 CYS n 1 188 VAL n 1 189 ALA n 1 190 THR n 1 191 ASN n 1 192 SER n 1 193 ALA n 1 194 GLY n 1 195 THR n 1 196 ARG n 1 197 TYR n 1 198 SER n 1 199 ALA n 1 200 PRO n 1 201 ALA n 1 202 ASN n 1 203 LEU n 1 204 TYR n 1 205 VAL n 1 206 ARG n 1 207 GLU n 1 208 LEU n 1 209 ARG n 1 210 GLU n 1 211 VAL n 1 212 ARG n 1 213 ARG n 1 214 VAL n 1 215 PRO n 1 216 PRO n 1 217 ARG n 1 218 PHE n 1 219 SER n 1 220 ILE n 1 221 PRO n 1 222 PRO n 1 223 THR n 1 224 ASN n 1 225 HIS n 1 226 GLU n 1 227 ILE n 1 228 MET n 1 229 PRO n 1 230 GLY n 1 231 GLY n 1 232 SER n 1 233 VAL n 1 234 ASN n 1 235 ILE n 1 236 THR n 1 237 CYS n 1 238 VAL n 1 239 ALA n 1 240 VAL n 1 241 GLY n 1 242 SER n 1 243 PRO n 1 244 MET n 1 245 PRO n 1 246 TYR n 1 247 VAL n 1 248 LYS n 1 249 TRP n 1 250 MET n 1 251 LEU n 1 252 GLY n 1 253 ALA n 1 254 GLU n 1 255 ASP n 1 256 LEU n 1 257 THR n 1 258 PRO n 1 259 GLU n 1 260 ASP n 1 261 ASP n 1 262 MET n 1 263 PRO n 1 264 ILE n 1 265 GLY n 1 266 ARG n 1 267 ASN n 1 268 VAL n 1 269 LEU n 1 270 GLU n 1 271 LEU n 1 272 ASN n 1 273 ASP n 1 274 VAL n 1 275 ARG n 1 276 GLN n 1 277 SER n 1 278 ALA n 1 279 ASN n 1 280 TYR n 1 281 THR n 1 282 CYS n 1 283 VAL n 1 284 ALA n 1 285 MET n 1 286 SER n 1 287 THR n 1 288 LEU n 1 289 GLY n 1 290 VAL n 1 291 ILE n 1 292 GLU n 1 293 ALA n 1 294 ILE n 1 295 ALA n 1 296 GLN n 1 297 ILE n 1 298 THR n 1 299 VAL n 1 300 LYS n 1 301 ALA n 1 302 LEU n 1 303 PRO n 1 304 LYS n 1 305 PRO n 1 306 PRO n 1 307 GLY n 1 308 THR n 1 309 PRO n 1 310 VAL n 1 311 VAL n 1 312 THR n 1 313 GLU n 1 314 SER n 1 315 THR n 1 316 ALA n 1 317 THR n 1 318 SER n 1 319 ILE n 1 320 THR n 1 321 LEU n 1 322 THR n 1 323 TRP n 1 324 ASP n 1 325 SER n 1 326 GLY n 1 327 ASN n 1 328 PRO n 1 329 GLU n 1 330 PRO n 1 331 VAL n 1 332 SER n 1 333 TYR n 1 334 TYR n 1 335 ILE n 1 336 ILE n 1 337 GLN n 1 338 HIS n 1 339 LYS n 1 340 PRO n 1 341 LYS n 1 342 ASN n 1 343 SER n 1 344 GLU n 1 345 GLU n 1 346 PRO n 1 347 TYR n 1 348 LYS n 1 349 GLU n 1 350 ILE n 1 351 ASP n 1 352 GLY n 1 353 ILE n 1 354 ALA n 1 355 THR n 1 356 THR n 1 357 ARG n 1 358 TYR n 1 359 SER n 1 360 VAL n 1 361 ALA n 1 362 GLY n 1 363 LEU n 1 364 SER n 1 365 PRO n 1 366 TYR n 1 367 SER n 1 368 ASP n 1 369 TYR n 1 370 GLU n 1 371 PHE n 1 372 ARG n 1 373 VAL n 1 374 VAL n 1 375 ALA n 1 376 VAL n 1 377 ASN n 1 378 ASN n 1 379 ILE n 1 380 GLY n 1 381 ARG n 1 382 GLY n 1 383 PRO n 1 384 ALA n 1 385 SER n 1 386 GLU n 1 387 PRO n 1 388 VAL n 1 389 LEU n 1 390 THR n 1 391 GLN n 1 392 THR n 1 393 SER n 1 394 GLU n 1 395 GLN n 1 396 ALA n 1 397 PRO n 1 398 SER n 1 399 SER n 1 400 ALA n 1 401 PRO n 1 402 ARG n 1 403 ASP n 1 404 VAL n 1 405 GLN n 1 406 ALA n 1 407 ARG n 1 408 MET n 1 409 LEU n 1 410 SER n 1 411 SER n 1 412 THR n 1 413 THR n 1 414 ILE n 1 415 LEU n 1 416 VAL n 1 417 GLN n 1 418 TRP n 1 419 LYS n 1 420 GLU n 1 421 PRO n 1 422 GLU n 1 423 GLU n 1 424 PRO n 1 425 ASN n 1 426 GLY n 1 427 GLN n 1 428 ILE n 1 429 GLN n 1 430 GLY n 1 431 TYR n 1 432 ARG n 1 433 VAL n 1 434 TYR n 1 435 TYR n 1 436 THR n 1 437 MET n 1 438 ASP n 1 439 PRO n 1 440 THR n 1 441 GLN n 1 442 HIS n 1 443 VAL n 1 444 ASN n 1 445 ASN n 1 446 TRP n 1 447 MET n 1 448 LYS n 1 449 HIS n 1 450 ASN n 1 451 VAL n 1 452 ALA n 1 453 ASP n 1 454 SER n 1 455 GLN n 1 456 ILE n 1 457 THR n 1 458 THR n 1 459 ILE n 1 460 GLY n 1 461 ASN n 1 462 LEU n 1 463 VAL n 1 464 PRO n 1 465 GLN n 1 466 LYS n 1 467 THR n 1 468 TYR n 1 469 SER n 1 470 VAL n 1 471 LYS n 1 472 VAL n 1 473 LEU n 1 474 ALA n 1 475 PHE n 1 476 THR n 1 477 SER n 1 478 ILE n 1 479 GLY n 1 480 ASP n 1 481 GLY n 1 482 PRO n 1 483 LEU n 1 484 SER n 1 485 SER n 1 486 ASP n 1 487 ILE n 1 488 GLN n 1 489 VAL n 1 490 ILE n 1 491 THR n 1 492 GLN n 1 493 THR n 1 494 GLY n 1 495 VAL n 1 496 PRO n 1 497 GLY n 1 498 GLN n 1 499 PRO n 1 500 LEU n 1 501 ASN n 1 502 PHE n 1 503 LYS n 1 504 ALA n 1 505 GLU n 1 506 PRO n 1 507 GLU n 1 508 SER n 1 509 GLU n 1 510 THR n 1 511 SER n 1 512 ILE n 1 513 LEU n 1 514 LEU n 1 515 SER n 1 516 TRP n 1 517 THR n 1 518 PRO n 1 519 PRO n 1 520 ARG n 1 521 SER n 1 522 ASP n 1 523 THR n 1 524 ILE n 1 525 ALA n 1 526 SER n 1 527 TYR n 1 528 GLU n 1 529 LEU n 1 530 VAL n 1 531 TYR n 1 532 ARG n 1 533 ASP n 1 534 GLY n 1 535 ASP n 1 536 GLN n 1 537 GLY n 1 538 GLU n 1 539 GLU n 1 540 GLN n 1 541 ARG n 1 542 ILE n 1 543 THR n 1 544 ILE n 1 545 GLU n 1 546 PRO n 1 547 GLY n 1 548 THR n 1 549 SER n 1 550 TYR n 1 551 ARG n 1 552 LEU n 1 553 GLN n 1 554 GLY n 1 555 LEU n 1 556 LYS n 1 557 PRO n 1 558 ASN n 1 559 SER n 1 560 LEU n 1 561 TYR n 1 562 TYR n 1 563 PHE n 1 564 ARG n 1 565 LEU n 1 566 SER n 1 567 ALA n 1 568 ARG n 1 569 SER n 1 570 PRO n 1 571 GLN n 1 572 GLY n 1 573 LEU n 1 574 GLY n 1 575 ALA n 1 576 SER n 1 577 THR n 1 578 ALA n 1 579 GLU n 1 580 ILE n 1 581 SER n 1 582 ALA n 1 583 ARG n 1 584 THR n 1 585 MET n 1 586 GLN n 1 587 SER n 1 588 MET n 1 589 PHE n 1 590 ALA n 1 591 LYS n 1 592 ASN n 1 593 PHE n 1 594 HIS n 1 595 VAL n 1 596 LYS n 1 597 ALA n 1 598 VAL n 1 599 MET n 1 600 LYS n 1 601 THR n 1 602 SER n 1 603 VAL n 1 604 LEU n 1 605 LEU n 1 606 SER n 1 607 TRP n 1 608 GLU n 1 609 ILE n 1 610 PRO n 1 611 GLU n 1 612 ASN n 1 613 TYR n 1 614 ASN n 1 615 SER n 1 616 ALA n 1 617 MET n 1 618 PRO n 1 619 PHE n 1 620 LYS n 1 621 ILE n 1 622 LEU n 1 623 TYR n 1 624 ASP n 1 625 ASP n 1 626 GLY n 1 627 LYS n 1 628 MET n 1 629 VAL n 1 630 GLU n 1 631 GLU n 1 632 VAL n 1 633 ASP n 1 634 GLY n 1 635 ARG n 1 636 ALA n 1 637 THR n 1 638 GLN n 1 639 LYS n 1 640 LEU n 1 641 ILE n 1 642 VAL n 1 643 ASN n 1 644 LEU n 1 645 LYS n 1 646 PRO n 1 647 GLU n 1 648 LYS n 1 649 SER n 1 650 TYR n 1 651 SER n 1 652 PHE n 1 653 VAL n 1 654 LEU n 1 655 THR n 1 656 ASN n 1 657 ARG n 1 658 GLY n 1 659 ASN n 1 660 SER n 1 661 ALA n 1 662 GLY n 1 663 GLY n 1 664 LEU n 1 665 GLN n 1 666 HIS n 1 667 ARG n 1 668 VAL n 1 669 THR n 1 670 ALA n 1 671 LYS n 1 672 THR n 1 673 ALA n 1 674 PRO n 1 675 ASP n 1 676 VAL n 1 677 LEU n 1 678 ARG n 1 679 THR n 1 680 LYS n 1 681 PRO n 1 682 ALA n 1 683 PHE n 1 684 ILE n 1 685 GLY n 1 686 LYS n 1 687 THR n 1 688 ASN n 1 689 LEU n 1 690 ASP n 1 691 GLY n 1 692 MET n 1 693 ILE n 1 694 THR n 1 695 VAL n 1 696 GLN n 1 697 LEU n 1 698 PRO n 1 699 ASP n 1 700 VAL n 1 701 PRO n 1 702 ALA n 1 703 ASN n 1 704 GLU n 1 705 ASN n 1 706 ILE n 1 707 LYS n 1 708 GLY n 1 709 TYR n 1 710 TYR n 1 711 ILE n 1 712 ILE n 1 713 ILE n 1 714 VAL n 1 715 PRO n 1 716 LEU n 1 717 LYS n 1 718 LYS n 1 719 SER n 1 720 ARG n 1 721 GLY n 1 722 LYS n 1 723 PHE n 1 724 ILE n 1 725 LYS n 1 726 PRO n 1 727 TRP n 1 728 GLU n 1 729 SER n 1 730 PRO n 1 731 ASP n 1 732 GLU n 1 733 MET n 1 734 GLU n 1 735 LEU n 1 736 ASP n 1 737 GLU n 1 738 LEU n 1 739 LEU n 1 740 LYS n 1 741 GLU n 1 742 ILE n 1 743 SER n 1 744 ARG n 1 745 LYS n 1 746 ARG n 1 747 ARG n 1 748 SER n 1 749 ILE n 1 750 ARG n 1 751 TYR n 1 752 GLY n 1 753 ARG n 1 754 GLU n 1 755 VAL n 1 756 GLU n 1 757 LEU n 1 758 LYS n 1 759 PRO n 1 760 TYR n 1 761 ILE n 1 762 ALA n 1 763 ALA n 1 764 HIS n 1 765 PHE n 1 766 ASP n 1 767 VAL n 1 768 LEU n 1 769 PRO n 1 770 THR n 1 771 GLU n 1 772 PHE n 1 773 THR n 1 774 LEU n 1 775 GLY n 1 776 ASP n 1 777 ASP n 1 778 LYS n 1 779 HIS n 1 780 TYR n 1 781 GLY n 1 782 GLY n 1 783 PHE n 1 784 THR n 1 785 ASN n 1 786 LYS n 1 787 GLN n 1 788 LEU n 1 789 GLN n 1 790 SER n 1 791 GLY n 1 792 GLN n 1 793 GLU n 1 794 TYR n 1 795 VAL n 1 796 PHE n 1 797 PHE n 1 798 VAL n 1 799 LEU n 1 800 ALA n 1 801 VAL n 1 802 MET n 1 803 ASP n 1 804 HIS n 1 805 ALA n 1 806 GLU n 1 807 SER n 1 808 LYS n 1 809 MET n 1 810 TYR n 1 811 ALA n 1 812 THR n 1 813 SER n 1 814 PRO n 1 815 TYR n 1 816 SER n 1 817 ASP n 1 818 PRO n 1 819 VAL n 1 820 VAL n 1 821 SER n 1 822 MET n 1 823 ASP n 1 824 LEU n 1 825 ASP n 1 826 PRO n 1 827 GLN n 1 828 PRO n 1 829 ILE n 1 830 THR n 1 831 ASP n 1 832 GLU n 1 833 GLU n 1 834 GLU n 1 835 LYS n 1 836 HIS n 1 837 HIS n 1 838 HIS n 1 839 HIS n 1 840 HIS n 1 841 HIS n 2 1 ALA n 2 2 GLN n 2 3 PRO n 2 4 ALA n 2 5 ALA n 2 6 ARG n 2 7 ASP n 2 8 LEU n 2 9 LYS n 2 10 VAL n 2 11 VAL n 2 12 THR n 2 13 LYS n 2 14 ARG n 2 15 GLY n 2 16 SER n 2 17 ALA n 2 18 ASP n 2 19 GLY n 2 20 CYS n 2 21 THR n 2 22 ASP n 2 23 TRP n 2 24 SER n 2 25 VAL n 2 26 ASP n 2 27 ILE n 2 28 LYS n 2 29 LYS n 2 30 TYR n 2 31 GLN n 2 32 VAL n 2 33 LEU n 2 34 VAL n 2 35 GLY n 2 36 GLU n 2 37 PRO n 2 38 VAL n 2 39 ARG n 2 40 ILE n 2 41 LYS n 2 42 CYS n 2 43 ALA n 2 44 LEU n 2 45 PHE n 2 46 TYR n 2 47 GLY n 2 48 TYR n 2 49 ILE n 2 50 ARG n 2 51 THR n 2 52 ASN n 2 53 TYR n 2 54 SER n 2 55 LEU n 2 56 ALA n 2 57 GLN n 2 58 SER n 2 59 ALA n 2 60 GLY n 2 61 LEU n 2 62 SER n 2 63 LEU n 2 64 MET n 2 65 TRP n 2 66 TYR n 2 67 LYS n 2 68 SER n 2 69 SER n 2 70 GLY n 2 71 PRO n 2 72 GLY n 2 73 ASP n 2 74 PHE n 2 75 GLU n 2 76 GLU n 2 77 PRO n 2 78 ILE n 2 79 ALA n 2 80 PHE n 2 81 ASP n 2 82 GLY n 2 83 SER n 2 84 ARG n 2 85 MET n 2 86 SER n 2 87 LYS n 2 88 GLU n 2 89 GLU n 2 90 ASP n 2 91 SER n 2 92 ILE n 2 93 TRP n 2 94 PHE n 2 95 ARG n 2 96 PRO n 2 97 THR n 2 98 LEU n 2 99 LEU n 2 100 GLN n 2 101 ASP n 2 102 SER n 2 103 GLY n 2 104 LEU n 2 105 TYR n 2 106 ALA n 2 107 CYS n 2 108 VAL n 2 109 ILE n 2 110 ARG n 2 111 ASN n 2 112 SER n 2 113 THR n 2 114 TYR n 2 115 CYS n 2 116 MET n 2 117 LYS n 2 118 VAL n 2 119 SER n 2 120 ILE n 2 121 SER n 2 122 LEU n 2 123 THR n 2 124 VAL n 2 125 GLY n 2 126 GLU n 2 127 ASN n 2 128 ASP n 2 129 THR n 2 130 GLY n 2 131 LEU n 2 132 CYS n 2 133 TYR n 2 134 ASN n 2 135 SER n 2 136 LYS n 2 137 MET n 2 138 LYS n 2 139 TYR n 2 140 PHE n 2 141 GLU n 2 142 LYS n 2 143 ALA n 2 144 GLU n 2 145 LEU n 2 146 SER n 2 147 LYS n 2 148 SER n 2 149 LYS n 2 150 GLU n 2 151 ILE n 2 152 SER n 2 153 CYS n 2 154 ARG n 2 155 ASP n 2 156 ILE n 2 157 GLU n 2 158 ASP n 2 159 PHE n 2 160 LEU n 2 161 LEU n 2 162 PRO n 2 163 THR n 2 164 ARG n 2 165 GLU n 2 166 PRO n 2 167 GLU n 2 168 ILE n 2 169 LEU n 2 170 TRP n 2 171 TYR n 2 172 LYS n 2 173 GLU n 2 174 CYS n 2 175 ARG n 2 176 THR n 2 177 LYS n 2 178 ALA n 2 179 TRP n 2 180 ARG n 2 181 PRO n 2 182 SER n 2 183 ILE n 2 184 VAL n 2 185 PHE n 2 186 LYS n 2 187 ARG n 2 188 ASP n 2 189 THR n 2 190 LEU n 2 191 LEU n 2 192 ILE n 2 193 LYS n 2 194 GLU n 2 195 VAL n 2 196 LYS n 2 197 GLU n 2 198 ASP n 2 199 ASP n 2 200 ILE n 2 201 GLY n 2 202 ASN n 2 203 TYR n 2 204 THR n 2 205 CYS n 2 206 GLU n 2 207 LEU n 2 208 LYS n 2 209 TYR n 2 210 GLY n 2 211 GLY n 2 212 PHE n 2 213 VAL n 2 214 VAL n 2 215 ARG n 2 216 ARG n 2 217 THR n 2 218 THR n 2 219 GLU n 2 220 LEU n 2 221 THR n 2 222 VAL n 2 223 THR n 2 224 ALA n 2 225 PRO n 2 226 LEU n 2 227 THR n 2 228 ASP n 2 229 LYS n 2 230 PRO n 2 231 PRO n 2 232 LYS n 2 233 LEU n 2 234 LEU n 2 235 TYR n 2 236 PRO n 2 237 MET n 2 238 GLU n 2 239 SER n 2 240 LYS n 2 241 LEU n 2 242 THR n 2 243 VAL n 2 244 GLN n 2 245 GLU n 2 246 THR n 2 247 GLN n 2 248 LEU n 2 249 GLY n 2 250 GLY n 2 251 SER n 2 252 ALA n 2 253 ASN n 2 254 LEU n 2 255 THR n 2 256 CYS n 2 257 ARG n 2 258 ALA n 2 259 PHE n 2 260 PHE n 2 261 GLY n 2 262 TYR n 2 263 SER n 2 264 GLY n 2 265 ASP n 2 266 VAL n 2 267 SER n 2 268 PRO n 2 269 LEU n 2 270 ILE n 2 271 TYR n 2 272 TRP n 2 273 MET n 2 274 LYS n 2 275 GLY n 2 276 GLU n 2 277 LYS n 2 278 PHE n 2 279 ILE n 2 280 GLU n 2 281 ASP n 2 282 LEU n 2 283 ASP n 2 284 GLU n 2 285 ASN n 2 286 ARG n 2 287 VAL n 2 288 TRP n 2 289 GLU n 2 290 SER n 2 291 ASP n 2 292 ILE n 2 293 ARG n 2 294 ILE n 2 295 LEU n 2 296 LYS n 2 297 GLU n 2 298 HIS n 2 299 LEU n 2 300 GLY n 2 301 GLU n 2 302 GLN n 2 303 GLU n 2 304 VAL n 2 305 SER n 2 306 ILE n 2 307 SER n 2 308 LEU n 2 309 ILE n 2 310 VAL n 2 311 ASP n 2 312 SER n 2 313 VAL n 2 314 GLU n 2 315 GLU n 2 316 GLY n 2 317 ASP n 2 318 LEU n 2 319 GLY n 2 320 ASN n 2 321 TYR n 2 322 SER n 2 323 CYS n 2 324 TYR n 2 325 VAL n 2 326 GLU n 2 327 ASN n 2 328 GLY n 2 329 ASN n 2 330 GLY n 2 331 ARG n 2 332 ARG n 2 333 HIS n 2 334 ALA n 2 335 SER n 2 336 VAL n 2 337 LEU n 2 338 LEU n 2 339 HIS n 2 340 LYS n 2 341 ARG n 2 342 LYS n 2 343 HIS n 2 344 HIS n 2 345 HIS n 2 346 HIS n 2 347 HIS n 2 348 HIS n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample 'Biological sequence' 1 841 Mouse ? Ptprd ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Freestyle 293-F' ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample 'Biological sequence' 1 348 Mouse ? Il1rapl1 ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Freestyle 293-F' ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin 1 UNP PTPRD_MOUSE Q64487 Q64487-12 1 ;ETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVA SNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRS ESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAV GSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSIT LTWDSGNPEPVSYYIIQHKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSA PRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGD GPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQGEEQRITIEPGTSYRLQGLKPNSL YYFRLSARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKL IVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPDVPANENIKGYYIIIVPLKKSR GKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLA VMDHAESKMYATSPYSDPVVSMDLDPQPITDEEE ; 21 2 UNP IRPL1_MOUSE P59823 ? 2 ;LKVVTKRGSADGCTDWSVDIKKYQVLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSK EEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPE ILWYKECRTKAWRPSIVFKRDTLLIKEVKEDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTVQETQ LGGSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVEN GNGRRHASVLLHKR ; 19 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4YH7 A 1 ? 834 ? Q64487 21 ? 854 ? 28 861 2 2 4YH7 B 8 ? 341 ? P59823 19 ? 352 ? 19 352 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 4YH7 LYS A 835 ? UNP Q64487 ? ? 'expression tag' 862 1 1 4YH7 HIS A 836 ? UNP Q64487 ? ? 'expression tag' 863 2 1 4YH7 HIS A 837 ? UNP Q64487 ? ? 'expression tag' 864 3 1 4YH7 HIS A 838 ? UNP Q64487 ? ? 'expression tag' 865 4 1 4YH7 HIS A 839 ? UNP Q64487 ? ? 'expression tag' 866 5 1 4YH7 HIS A 840 ? UNP Q64487 ? ? 'expression tag' 867 6 1 4YH7 HIS A 841 ? UNP Q64487 ? ? 'expression tag' 868 7 2 4YH7 ALA B 1 ? UNP P59823 ? ? 'expression tag' 12 8 2 4YH7 GLN B 2 ? UNP P59823 ? ? 'expression tag' 13 9 2 4YH7 PRO B 3 ? UNP P59823 ? ? 'expression tag' 14 10 2 4YH7 ALA B 4 ? UNP P59823 ? ? 'expression tag' 15 11 2 4YH7 ALA B 5 ? UNP P59823 ? ? 'expression tag' 16 12 2 4YH7 ARG B 6 ? UNP P59823 ? ? 'expression tag' 17 13 2 4YH7 ASP B 7 ? UNP P59823 ? ? 'expression tag' 18 14 2 4YH7 LYS B 342 ? UNP P59823 ? ? 'expression tag' 353 15 2 4YH7 HIS B 343 ? UNP P59823 ? ? 'expression tag' 354 16 2 4YH7 HIS B 344 ? UNP P59823 ? ? 'expression tag' 355 17 2 4YH7 HIS B 345 ? UNP P59823 ? ? 'expression tag' 356 18 2 4YH7 HIS B 346 ? UNP P59823 ? ? 'expression tag' 357 19 2 4YH7 HIS B 347 ? UNP P59823 ? ? 'expression tag' 358 20 2 4YH7 HIS B 348 ? UNP P59823 ? ? 'expression tag' 359 21 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 4YH7 _exptl.crystals_number ? _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 5.39 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 77.19 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH 6.0 _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '15% PEG4000, 0.1 M MES' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'RAYONIX MX225HE' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2011-06-16 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.000 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'SPRING-8 BEAMLINE BL41XU' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 1.000 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline BL41XU _diffrn_source.pdbx_synchrotron_site SPring-8 # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 4YH7 _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 4.4 _reflns.d_resolution_low 50.0 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 17618 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 95.6 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 4.2 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value 0.072 _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 17.7 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _reflns_shell.d_res_high 4.4 _reflns_shell.d_res_low 4.48 _reflns_shell.meanI_over_sigI_all ? _reflns_shell.meanI_over_sigI_obs 2.2 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.number_unique_obs ? _reflns_shell.percent_possible_all 86.0 _reflns_shell.percent_possible_obs ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.Rmerge_I_obs 0.424 _reflns_shell.meanI_over_sigI_gt ? _reflns_shell.meanI_over_uI_all ? _reflns_shell.meanI_over_uI_gt ? _reflns_shell.number_measured_gt ? _reflns_shell.number_unique_gt ? _reflns_shell.percent_possible_gt ? _reflns_shell.Rmerge_F_gt ? _reflns_shell.Rmerge_I_gt ? _reflns_shell.pdbx_redundancy 2.2 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_netI_over_sigmaI_all ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_rejects ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_CC_half ? _reflns_shell.pdbx_R_split ? # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 4YH7 _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 17614 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.43 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 39.090 _refine.ls_d_res_high 4.400 _refine.ls_percent_reflns_obs 95.42 _refine.ls_R_factor_obs 0.2920 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.2904 _refine.ls_R_factor_R_free 0.3246 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.09 _refine.ls_number_reflns_R_free 896 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean ? _refine.aniso_B[1][1] ? _refine.aniso_B[2][2] ? _refine.aniso_B[3][3] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][3] ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_ls_cross_valid_method 'FREE R-VALUE' _refine.details ? _refine.pdbx_starting_model '4YFC, 2DJU, 2DLH' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.66 _refine.pdbx_overall_phase_error 37.84 _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 7123 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 117 _refine_hist.number_atoms_solvent 0 _refine_hist.number_atoms_total 7240 _refine_hist.d_res_high 4.400 _refine_hist.d_res_low 39.090 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function f_bond_d 0.006 ? ? 7414 'X-RAY DIFFRACTION' ? f_angle_d 1.575 ? ? 10078 'X-RAY DIFFRACTION' ? f_dihedral_angle_d 19.831 ? ? 2810 'X-RAY DIFFRACTION' ? f_chiral_restr 0.064 ? ? 1141 'X-RAY DIFFRACTION' ? f_plane_restr 0.008 ? ? 1297 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_all _refine_ls_shell.R_factor_all _refine_ls_shell.R_factor_obs _refine_ls_shell.number_reflns_obs 'X-RAY DIFFRACTION' . 4.3996 4.6748 2526 0.3324 87.00 0.3566 . . 129 . . . . 'X-RAY DIFFRACTION' . 4.6748 5.0350 2660 0.2937 93.00 0.3307 . . 169 . . . . 'X-RAY DIFFRACTION' . 5.0350 5.5405 2780 0.2791 97.00 0.3165 . . 164 . . . . 'X-RAY DIFFRACTION' . 5.5405 6.3392 2853 0.2676 97.00 0.3234 . . 137 . . . . 'X-RAY DIFFRACTION' . 6.3392 7.9756 2907 0.3152 99.00 0.3302 . . 149 . . . . 'X-RAY DIFFRACTION' . 7.9756 39.0917 2992 0.2821 99.00 0.3185 . . 148 . . . . # _struct.entry_id 4YH7 _struct.title 'Crystal structure of PTPdelta ectodomain in complex with IL1RAPL1' _struct.pdbx_descriptor 'Receptor protein tyrosine phosphatase delta, Interleukin-1 receptor accessory protein like 1' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 4YH7 _struct_keywords.text 'Trans-synaptic complex, Synapse organizer, HYDROLASE-IMMUNE SYSTEM complex' _struct_keywords.pdbx_keywords 'HYDROLASE/IMMUNE SYSTEM' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 3 ? E N N 3 ? F N N 3 ? G N N 3 ? H N N 3 ? I N N 4 ? J N N 5 ? K N N 5 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 ARG A 97 ? ILE A 101 ? ARG A 124 ILE A 128 5 ? 5 HELX_P HELX_P2 AA2 GLU A 178 ? GLN A 182 ? GLU A 205 GLN A 209 5 ? 5 HELX_P HELX_P3 AA3 HIS A 442 ? TRP A 446 ? HIS A 469 TRP A 473 5 ? 5 HELX_P HELX_P4 AA4 ALA B 43 ? TYR B 46 ? ALA B 54 TYR B 57 5 ? 4 HELX_P HELX_P5 AA5 ASN B 52 ? ALA B 59 ? ASN B 63 ALA B 70 1 ? 8 HELX_P HELX_P6 AA6 LEU B 98 ? SER B 102 ? LEU B 109 SER B 113 5 ? 5 HELX_P HELX_P7 AA7 LYS B 196 ? ILE B 200 ? LYS B 207 ILE B 211 5 ? 5 HELX_P HELX_P8 AA8 ILE B 279 ? ASP B 283 ? ILE B 290 ASP B 294 1 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 25 SG ? ? ? 1_555 A CYS 78 SG ? ? A CYS 52 A CYS 105 1_555 ? ? ? ? ? ? ? 2.031 ? disulf2 disulf ? ? A CYS 237 SG ? ? ? 1_555 A CYS 282 SG ? ? A CYS 264 A CYS 309 1_555 ? ? ? ? ? ? ? 2.031 ? disulf3 disulf ? ? B CYS 20 SG ? ? ? 1_555 B CYS 115 SG ? ? B CYS 31 B CYS 126 1_555 ? ? ? ? ? ? ? 2.030 ? disulf4 disulf ? ? B CYS 42 SG ? ? ? 1_555 B CYS 107 SG ? ? B CYS 53 B CYS 118 1_555 ? ? ? ? ? ? ? 2.036 ? disulf5 disulf ? ? B CYS 132 SG ? ? ? 1_555 B CYS 174 SG ? ? B CYS 143 B CYS 185 1_555 ? ? ? ? ? ? ? 2.035 ? disulf6 disulf ? ? B CYS 153 SG ? ? ? 1_555 B CYS 205 SG ? ? B CYS 164 B CYS 216 1_555 ? ? ? ? ? ? ? 2.031 ? disulf7 disulf ? ? B CYS 256 SG ? ? ? 1_555 B CYS 323 SG ? ? B CYS 267 B CYS 334 1_555 ? ? ? ? ? ? ? 2.034 ? covale1 covale one ? B ASN 111 ND2 ? ? ? 1_555 C NAG . C1 ? ? B ASN 122 B NAG 401 1_555 ? ? ? ? ? ? ? 1.457 ? covale2 covale one ? B ASN 127 ND2 ? ? ? 1_555 D NAG . C1 ? ? B ASN 138 B NAG 402 1_555 ? ? ? ? ? ? ? 1.449 ? covale3 covale one ? B ASN 202 ND2 ? ? ? 1_555 E NAG . C1 ? ? B ASN 213 B NAG 403 1_555 ? ? ? ? ? ? ? 1.442 ? covale4 covale one ? B ASN 253 ND2 ? ? ? 1_555 G NAG . C1 ? ? B ASN 264 B NAG 405 1_555 ? ? ? ? ? ? ? 1.445 ? covale5 covale both ? E NAG . O4 ? ? ? 1_555 F NAG . C1 ? ? B NAG 403 B NAG 404 1_555 ? ? ? ? ? ? ? 1.442 ? covale6 covale both ? G NAG . O4 ? ? ? 1_555 H NAG . C1 ? ? B NAG 405 B NAG 406 1_555 ? ? ? ? ? ? ? 1.448 ? covale7 covale both ? H NAG . O4 ? ? ? 1_555 I BMA . C1 ? ? B NAG 406 B BMA 407 1_555 ? ? ? ? ? ? ? 1.443 ? covale8 covale one ? I BMA . O3 ? ? ? 1_555 J MAN . C1 ? ? B BMA 407 B MAN 408 1_555 ? ? ? ? ? ? ? 1.464 ? covale9 covale one ? I BMA . O6 ? ? ? 1_555 K MAN . C1 ? ? B BMA 407 B MAN 409 1_555 ? ? ? ? ? ? ? 1.456 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ASP 30 A . ? ASP 57 A PRO 31 A ? PRO 58 A 1 1.06 2 GLN 65 A . ? GLN 92 A PRO 66 A ? PRO 93 A 1 -1.91 3 THR 69 A . ? THR 96 A PRO 70 A ? PRO 97 A 1 -2.58 4 ASN 132 A . ? ASN 159 A PRO 133 A ? PRO 160 A 1 2.65 5 SER 242 A . ? SER 269 A PRO 243 A ? PRO 270 A 1 1.34 6 PRO 71 B . ? PRO 82 B GLY 72 B ? GLY 83 B 1 -1.69 7 ARG 95 B . ? ARG 106 B PRO 96 B ? PRO 107 B 1 -0.38 8 GLY 210 B . ? GLY 221 B GLY 211 B ? GLY 222 B 1 7.04 9 TYR 235 B . ? TYR 246 B PRO 236 B ? PRO 247 B 1 -4.83 10 LEU 299 B . ? LEU 310 B GLY 300 B ? GLY 311 B 1 -10.61 11 GLU 315 B . ? GLU 326 B GLY 316 B ? GLY 327 B 1 9.93 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 4 ? AA2 ? 5 ? AA3 ? 4 ? AA4 ? 5 ? AA5 ? 4 ? AA6 ? 3 ? AA7 ? 4 ? AA8 ? 4 ? AA9 ? 3 ? AB1 ? 4 ? AB2 ? 3 ? AB3 ? 3 ? AB4 ? 3 ? AB5 ? 4 ? AB6 ? 4 ? AB7 ? 3 ? AB8 ? 4 ? AB9 ? 2 ? AC1 ? 4 ? AC2 ? 3 ? AC3 ? 4 ? AC4 ? 4 ? AC5 ? 5 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? anti-parallel AA1 3 4 ? anti-parallel AA2 1 2 ? parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA2 4 5 ? anti-parallel AA3 1 2 ? anti-parallel AA3 2 3 ? anti-parallel AA3 3 4 ? anti-parallel AA4 1 2 ? parallel AA4 2 3 ? anti-parallel AA4 3 4 ? anti-parallel AA4 4 5 ? anti-parallel AA5 1 2 ? parallel AA5 2 3 ? anti-parallel AA5 3 4 ? anti-parallel AA6 1 2 ? anti-parallel AA6 2 3 ? anti-parallel AA7 1 2 ? parallel AA7 2 3 ? anti-parallel AA7 3 4 ? anti-parallel AA8 1 2 ? parallel AA8 2 3 ? anti-parallel AA8 3 4 ? anti-parallel AA9 1 2 ? anti-parallel AA9 2 3 ? anti-parallel AB1 1 2 ? anti-parallel AB1 2 3 ? anti-parallel AB1 3 4 ? anti-parallel AB2 1 2 ? anti-parallel AB2 2 3 ? anti-parallel AB3 1 2 ? anti-parallel AB3 2 3 ? anti-parallel AB4 1 2 ? anti-parallel AB4 2 3 ? anti-parallel AB5 1 2 ? anti-parallel AB5 2 3 ? anti-parallel AB5 3 4 ? anti-parallel AB6 1 2 ? anti-parallel AB6 2 3 ? anti-parallel AB6 3 4 ? anti-parallel AB7 1 2 ? parallel AB7 2 3 ? parallel AB8 1 2 ? parallel AB8 2 3 ? anti-parallel AB8 3 4 ? anti-parallel AB9 1 2 ? anti-parallel AC1 1 2 ? parallel AC1 2 3 ? anti-parallel AC1 3 4 ? anti-parallel AC2 1 2 ? anti-parallel AC2 2 3 ? anti-parallel AC3 1 2 ? anti-parallel AC3 2 3 ? anti-parallel AC3 3 4 ? anti-parallel AC4 1 2 ? anti-parallel AC4 2 3 ? anti-parallel AC4 3 4 ? anti-parallel AC5 1 2 ? parallel AC5 2 3 ? anti-parallel AC5 3 4 ? anti-parallel AC5 4 5 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 ARG A 5 ? ARG A 8 ? ARG A 32 ARG A 35 AA1 2 ALA A 21 ? THR A 28 ? ALA A 48 THR A 55 AA1 3 SER A 60 ? ILE A 64 ? SER A 87 ILE A 91 AA1 4 PHE A 49 ? GLU A 53 ? PHE A 76 GLU A 80 AA2 1 GLN A 13 ? VAL A 16 ? GLN A 40 VAL A 43 AA2 2 GLY A 85 ? LEU A 96 ? GLY A 112 LEU A 123 AA2 3 ALA A 74 ? ASN A 82 ? ALA A 101 ASN A 109 AA2 4 LYS A 34 ? LYS A 39 ? LYS A 61 LYS A 66 AA2 5 LYS A 42 ? LYS A 43 ? LYS A 69 LYS A 70 AA3 1 THR A 107 ? MET A 110 ? THR A 134 MET A 137 AA3 2 ALA A 123 ? SER A 130 ? ALA A 150 SER A 157 AA3 3 ILE A 168 ? ILE A 174 ? ILE A 195 ILE A 201 AA3 4 ILE A 155 ? ARG A 159 ? ILE A 182 ARG A 186 AA4 1 LYS A 115 ? GLU A 118 ? LYS A 142 GLU A 145 AA4 2 ALA A 201 ? ARG A 206 ? ALA A 228 ARG A 233 AA4 3 GLY A 183 ? ASN A 191 ? GLY A 210 ASN A 218 AA4 4 GLU A 136 ? LYS A 141 ? GLU A 163 LYS A 168 AA4 5 LEU A 144 ? PRO A 145 ? LEU A 171 PRO A 172 AA5 1 LYS A 115 ? GLU A 118 ? LYS A 142 GLU A 145 AA5 2 ALA A 201 ? ARG A 206 ? ALA A 228 ARG A 233 AA5 3 GLY A 183 ? ASN A 191 ? GLY A 210 ASN A 218 AA5 4 GLY A 194 ? TYR A 197 ? GLY A 221 TYR A 224 AA6 1 ARG A 217 ? ILE A 220 ? ARG A 244 ILE A 247 AA6 2 VAL A 233 ? VAL A 240 ? VAL A 260 VAL A 267 AA6 3 ARG A 266 ? LEU A 271 ? ARG A 293 LEU A 298 AA7 1 HIS A 225 ? GLU A 226 ? HIS A 252 GLU A 253 AA7 2 ILE A 294 ? THR A 298 ? ILE A 321 THR A 325 AA7 3 ALA A 278 ? MET A 285 ? ALA A 305 MET A 312 AA7 4 TYR A 246 ? MET A 250 ? TYR A 273 MET A 277 AA8 1 HIS A 225 ? GLU A 226 ? HIS A 252 GLU A 253 AA8 2 ILE A 294 ? THR A 298 ? ILE A 321 THR A 325 AA8 3 ALA A 278 ? MET A 285 ? ALA A 305 MET A 312 AA8 4 VAL A 290 ? ILE A 291 ? VAL A 317 ILE A 318 AA9 1 GLY A 307 ? SER A 314 ? GLY A 334 SER A 341 AA9 2 ILE A 319 ? ASP A 324 ? ILE A 346 ASP A 351 AA9 3 ARG A 357 ? VAL A 360 ? ARG A 384 VAL A 387 AB1 1 LYS A 348 ? ILE A 353 ? LYS A 375 ILE A 380 AB1 2 TYR A 333 ? LYS A 339 ? TYR A 360 LYS A 366 AB1 3 ASP A 368 ? VAL A 376 ? ASP A 395 VAL A 403 AB1 4 VAL A 388 ? GLN A 391 ? VAL A 415 GLN A 418 AB2 1 ARG A 402 ? MET A 408 ? ARG A 429 MET A 435 AB2 2 ILE A 414 ? LYS A 419 ? ILE A 441 LYS A 446 AB2 3 ILE A 456 ? ILE A 459 ? ILE A 483 ILE A 486 AB3 1 GLY A 430 ? VAL A 433 ? GLY A 457 VAL A 460 AB3 2 VAL A 470 ? PHE A 475 ? VAL A 497 PHE A 502 AB3 3 ASP A 480 ? ILE A 487 ? ASP A 507 ILE A 514 AB4 1 LEU A 500 ? GLU A 505 ? LEU A 527 GLU A 532 AB4 2 SER A 511 ? THR A 517 ? SER A 538 THR A 544 AB4 3 SER A 549 ? GLN A 553 ? SER A 576 GLN A 580 AB5 1 GLN A 540 ? ILE A 544 ? GLN A 567 ILE A 571 AB5 2 SER A 526 ? ASP A 533 ? SER A 553 ASP A 560 AB5 3 LEU A 560 ? ARG A 568 ? LEU A 587 ARG A 595 AB5 4 LEU A 573 ? SER A 576 ? LEU A 600 SER A 603 AB6 1 GLN A 540 ? ILE A 544 ? GLN A 567 ILE A 571 AB6 2 SER A 526 ? ASP A 533 ? SER A 553 ASP A 560 AB6 3 LEU A 560 ? ARG A 568 ? LEU A 587 ARG A 595 AB6 4 ILE A 580 ? ARG A 583 ? ILE A 607 ARG A 610 AB7 1 THR B 21 ? VAL B 25 ? THR B 32 VAL B 36 AB7 2 CYS B 115 ? GLY B 125 ? CYS B 126 GLY B 136 AB7 3 TYR B 30 ? LEU B 33 ? TYR B 41 LEU B 44 AB8 1 THR B 21 ? VAL B 25 ? THR B 32 VAL B 36 AB8 2 CYS B 115 ? GLY B 125 ? CYS B 126 GLY B 136 AB8 3 GLY B 103 ? ARG B 110 ? GLY B 114 ARG B 121 AB8 4 SER B 62 ? SER B 68 ? SER B 73 SER B 79 AB9 1 VAL B 38 ? LYS B 41 ? VAL B 49 LYS B 52 AB9 2 SER B 91 ? PHE B 94 ? SER B 102 PHE B 105 AC1 1 TYR B 139 ? GLU B 144 ? TYR B 150 GLU B 155 AC1 2 PHE B 212 ? THR B 223 ? PHE B 223 THR B 234 AC1 3 GLY B 201 ? TYR B 209 ? GLY B 212 TYR B 220 AC1 4 TYR B 171 ? LYS B 172 ? TYR B 182 LYS B 183 AC2 1 LYS B 149 ? ILE B 151 ? LYS B 160 ILE B 162 AC2 2 LEU B 190 ? ILE B 192 ? LEU B 201 ILE B 203 AC2 3 ILE B 183 ? PHE B 185 ? ILE B 194 PHE B 196 AC3 1 LYS B 232 ? TYR B 235 ? LYS B 243 TYR B 246 AC3 2 ALA B 252 ? PHE B 260 ? ALA B 263 PHE B 271 AC3 3 GLU B 301 ? VAL B 310 ? GLU B 312 VAL B 321 AC3 4 VAL B 287 ? GLU B 289 ? VAL B 298 GLU B 300 AC4 1 LYS B 232 ? TYR B 235 ? LYS B 243 TYR B 246 AC4 2 ALA B 252 ? PHE B 260 ? ALA B 263 PHE B 271 AC4 3 GLU B 301 ? VAL B 310 ? GLU B 312 VAL B 321 AC4 4 ARG B 293 ? HIS B 298 ? ARG B 304 HIS B 309 AC5 1 THR B 242 ? GLU B 245 ? THR B 253 GLU B 256 AC5 2 GLY B 330 ? HIS B 339 ? GLY B 341 HIS B 350 AC5 3 GLY B 319 ? ASN B 327 ? GLY B 330 ASN B 338 AC5 4 LEU B 269 ? LYS B 274 ? LEU B 280 LYS B 285 AC5 5 LYS B 277 ? PHE B 278 ? LYS B 288 PHE B 289 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N ARG A 5 ? N ARG A 32 O THR A 28 ? O THR A 55 AA1 2 3 N ALA A 21 ? N ALA A 48 O ILE A 64 ? O ILE A 91 AA1 3 4 O VAL A 61 ? O VAL A 88 N ILE A 52 ? N ILE A 79 AA2 1 2 N GLY A 15 ? N GLY A 42 O LEU A 96 ? O LEU A 123 AA2 2 3 O ILE A 87 ? O ILE A 114 N ALA A 80 ? N ALA A 107 AA2 3 4 O GLU A 77 ? O GLU A 104 N ASN A 38 ? N ASN A 65 AA2 4 5 N LYS A 39 ? N LYS A 66 O LYS A 42 ? O LYS A 69 AA3 1 2 N MET A 110 ? N MET A 137 O ALA A 128 ? O ALA A 155 AA3 2 3 N ALA A 123 ? N ALA A 150 O ILE A 174 ? O ILE A 201 AA3 3 4 O GLN A 173 ? O GLN A 200 N LYS A 156 ? N LYS A 183 AA4 1 2 N VAL A 117 ? N VAL A 144 O ARG A 206 ? O ARG A 233 AA4 2 3 O ALA A 201 ? O ALA A 228 N TYR A 185 ? N TYR A 212 AA4 3 4 O THR A 190 ? O THR A 217 N GLU A 136 ? N GLU A 163 AA4 4 5 N LYS A 141 ? N LYS A 168 O LEU A 144 ? O LEU A 171 AA5 1 2 N VAL A 117 ? N VAL A 144 O ARG A 206 ? O ARG A 233 AA5 2 3 O ALA A 201 ? O ALA A 228 N TYR A 185 ? N TYR A 212 AA5 3 4 N ALA A 189 ? N ALA A 216 O ARG A 196 ? O ARG A 223 AA6 1 2 N ARG A 217 ? N ARG A 244 O VAL A 240 ? O VAL A 267 AA6 2 3 N ILE A 235 ? N ILE A 262 O LEU A 269 ? O LEU A 296 AA7 1 2 N HIS A 225 ? N HIS A 252 O GLN A 296 ? O GLN A 323 AA7 2 3 O ALA A 295 ? O ALA A 322 N TYR A 280 ? N TYR A 307 AA7 3 4 O THR A 281 ? O THR A 308 N MET A 250 ? N MET A 277 AA8 1 2 N HIS A 225 ? N HIS A 252 O GLN A 296 ? O GLN A 323 AA8 2 3 O ALA A 295 ? O ALA A 322 N TYR A 280 ? N TYR A 307 AA8 3 4 N ALA A 284 ? N ALA A 311 O ILE A 291 ? O ILE A 318 AA9 1 2 N GLU A 313 ? N GLU A 340 O THR A 320 ? O THR A 347 AA9 2 3 N LEU A 321 ? N LEU A 348 O TYR A 358 ? O TYR A 385 AB1 1 2 O LYS A 348 ? O LYS A 375 N HIS A 338 ? N HIS A 365 AB1 2 3 N LYS A 339 ? N LYS A 366 O GLU A 370 ? O GLU A 397 AB1 3 4 N PHE A 371 ? N PHE A 398 O VAL A 388 ? O VAL A 415 AB2 1 2 N ARG A 407 ? N ARG A 434 O LEU A 415 ? O LEU A 442 AB2 2 3 N VAL A 416 ? N VAL A 443 O THR A 457 ? O THR A 484 AB3 1 2 N ARG A 432 ? N ARG A 459 O LEU A 473 ? O LEU A 500 AB3 2 3 N VAL A 470 ? N VAL A 497 O ILE A 487 ? O ILE A 514 AB4 1 2 N GLU A 505 ? N GLU A 532 O LEU A 513 ? O LEU A 540 AB4 2 3 N ILE A 512 ? N ILE A 539 O LEU A 552 ? O LEU A 579 AB5 1 2 O GLN A 540 ? O GLN A 567 N TYR A 531 ? N TYR A 558 AB5 2 3 N ARG A 532 ? N ARG A 559 O TYR A 562 ? O TYR A 589 AB5 3 4 N ALA A 567 ? N ALA A 594 O GLY A 574 ? O GLY A 601 AB6 1 2 O GLN A 540 ? O GLN A 567 N TYR A 531 ? N TYR A 558 AB6 2 3 N ARG A 532 ? N ARG A 559 O TYR A 562 ? O TYR A 589 AB6 3 4 N TYR A 561 ? N TYR A 588 O ALA A 582 ? O ALA A 609 AB7 1 2 N TRP B 23 ? N TRP B 34 O LYS B 117 ? O LYS B 128 AB7 2 3 O SER B 121 ? O SER B 132 N TYR B 30 ? N TYR B 41 AB8 1 2 N TRP B 23 ? N TRP B 34 O LYS B 117 ? O LYS B 128 AB8 2 3 O LEU B 122 ? O LEU B 133 N GLY B 103 ? N GLY B 114 AB8 3 4 O VAL B 108 ? O VAL B 119 N MET B 64 ? N MET B 75 AB9 1 2 N VAL B 38 ? N VAL B 49 O PHE B 94 ? O PHE B 105 AC1 1 2 N ALA B 143 ? N ALA B 154 O THR B 223 ? O THR B 234 AC1 2 3 O LEU B 220 ? O LEU B 231 N GLY B 201 ? N GLY B 212 AC1 3 4 O THR B 204 ? O THR B 215 N TYR B 171 ? N TYR B 182 AC2 1 2 N LYS B 149 ? N LYS B 160 O ILE B 192 ? O ILE B 203 AC2 2 3 O LEU B 191 ? O LEU B 202 N VAL B 184 ? N VAL B 195 AC3 1 2 N TYR B 235 ? N TYR B 246 O ARG B 257 ? O ARG B 268 AC3 2 3 N ALA B 252 ? N ALA B 263 O VAL B 310 ? O VAL B 321 AC3 3 4 O ILE B 309 ? O ILE B 320 N TRP B 288 ? N TRP B 299 AC4 1 2 N TYR B 235 ? N TYR B 246 O ARG B 257 ? O ARG B 268 AC4 2 3 N ALA B 252 ? N ALA B 263 O VAL B 310 ? O VAL B 321 AC4 3 4 O SER B 305 ? O SER B 316 N ARG B 293 ? N ARG B 304 AC5 1 2 N GLN B 244 ? N GLN B 255 O LEU B 337 ? O LEU B 348 AC5 2 3 O ARG B 332 ? O ARG B 343 N VAL B 325 ? N VAL B 336 AC5 3 4 O TYR B 324 ? O TYR B 335 N TYR B 271 ? N TYR B 282 AC5 4 5 N LYS B 274 ? N LYS B 285 O LYS B 277 ? O LYS B 288 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software B NAG 401 ? 4 'binding site for Mono-Saccharide NAG B 401 bound to ASN B 122' AC2 Software B NAG 402 ? 4 'binding site for Mono-Saccharide NAG B 402 bound to ASN B 138' AC3 Software B ASN 213 ? 4 'binding site for Poly-Saccharide residues NAG B 403 through NAG B 404 bound to ASN B 213' AC4 Software B ASN 264 ? 8 'binding site for Poly-Saccharide residues NAG B 405 through MAN B 409 bound to ASN B 264' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 ALA B 59 ? ALA B 70 . ? 1_555 ? 2 AC1 4 LEU B 61 ? LEU B 72 . ? 1_555 ? 3 AC1 4 ASN B 111 ? ASN B 122 . ? 1_555 ? 4 AC1 4 TYR B 114 ? TYR B 125 . ? 1_555 ? 5 AC2 4 ASN B 127 ? ASN B 138 . ? 1_555 ? 6 AC2 4 THR B 129 ? THR B 140 . ? 1_555 ? 7 AC2 4 GLY B 130 ? GLY B 141 . ? 1_555 ? 8 AC2 4 LEU B 131 ? LEU B 142 . ? 1_555 ? 9 AC3 4 TYR B 133 ? TYR B 144 . ? 1_555 ? 10 AC3 4 SER B 135 ? SER B 146 . ? 1_555 ? 11 AC3 4 GLU B 173 ? GLU B 184 . ? 1_555 ? 12 AC3 4 ASN B 202 ? ASN B 213 . ? 1_555 ? 13 AC4 8 ASN B 253 ? ASN B 264 . ? 1_555 ? 14 AC4 8 THR B 255 ? THR B 266 . ? 1_555 ? 15 AC4 8 ARG B 257 ? ARG B 268 . ? 1_555 ? 16 AC4 8 ARG B 293 ? ARG B 304 . ? 1_555 ? 17 AC4 8 LEU B 295 ? LEU B 306 . ? 1_555 ? 18 AC4 8 SER B 305 ? SER B 316 . ? 1_555 ? 19 AC4 8 SER B 307 ? SER B 318 . ? 1_555 ? 20 AC4 8 ILE B 309 ? ILE B 320 . ? 1_555 ? # _atom_sites.entry_id 4YH7 _atom_sites.fract_transf_matrix[1][1] 0.003493 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.003493 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.014248 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLU A 1 1 ? -59.253 -5.790 0.733 1.00 172.90 ? 28 GLU A N 1 ATOM 2 C CA . GLU A 1 1 ? -59.962 -6.584 -0.264 1.00 183.82 ? 28 GLU A CA 1 ATOM 3 C C . GLU A 1 1 ? -59.961 -5.884 -1.621 1.00 184.17 ? 28 GLU A C 1 ATOM 4 O O . GLU A 1 1 ? -60.164 -4.673 -1.704 1.00 174.19 ? 28 GLU A O 1 ATOM 5 C CB . GLU A 1 1 ? -61.395 -6.860 0.194 1.00 184.81 ? 28 GLU A CB 1 ATOM 6 C CG . GLU A 1 1 ? -61.481 -7.625 1.503 1.00 181.37 ? 28 GLU A CG 1 ATOM 7 C CD . GLU A 1 1 ? -62.908 -7.923 1.914 1.00 180.52 ? 28 GLU A CD 1 ATOM 8 O OE1 . GLU A 1 1 ? -63.322 -7.460 2.997 1.00 178.00 ? 28 GLU A OE1 1 ATOM 9 O OE2 . GLU A 1 1 ? -63.614 -8.622 1.156 1.00 180.04 ? 28 GLU A OE2 1 ATOM 10 N N . THR A 1 2 ? -59.739 -6.654 -2.683 1.00 186.99 ? 29 THR A N 1 ATOM 11 C CA . THR A 1 2 ? -59.876 -6.139 -4.041 1.00 181.21 ? 29 THR A CA 1 ATOM 12 C C . THR A 1 2 ? -60.885 -6.911 -4.894 1.00 178.71 ? 29 THR A C 1 ATOM 13 O O . THR A 1 2 ? -61.059 -8.118 -4.723 1.00 172.74 ? 29 THR A O 1 ATOM 14 C CB . THR A 1 2 ? -58.512 -6.156 -4.773 1.00 177.75 ? 29 THR A CB 1 ATOM 15 O OG1 . THR A 1 2 ? -58.053 -7.507 -4.908 1.00 174.22 ? 29 THR A OG1 1 ATOM 16 C CG2 . THR A 1 2 ? -57.477 -5.346 -4.004 1.00 168.81 ? 29 THR A CG2 1 ATOM 17 N N . PRO A 1 3 ? -61.558 -6.208 -5.820 1.00 180.00 ? 30 PRO A N 1 ATOM 18 C CA . PRO A 1 3 ? -62.516 -6.835 -6.733 1.00 179.62 ? 30 PRO A CA 1 ATOM 19 C C . PRO A 1 3 ? -61.756 -7.599 -7.816 1.00 192.27 ? 30 PRO A C 1 ATOM 20 O O . PRO A 1 3 ? -60.562 -7.345 -7.986 1.00 191.82 ? 30 PRO A O 1 ATOM 21 C CB . PRO A 1 3 ? -63.290 -5.641 -7.292 1.00 173.19 ? 30 PRO A CB 1 ATOM 22 C CG . PRO A 1 3 ? -62.282 -4.548 -7.309 1.00 174.17 ? 30 PRO A CG 1 ATOM 23 C CD . PRO A 1 3 ? -61.483 -4.750 -6.037 1.00 181.31 ? 30 PRO A CD 1 ATOM 24 N N . PRO A 1 4 ? -62.416 -8.532 -8.523 1.00 197.51 ? 31 PRO A N 1 ATOM 25 C CA . PRO A 1 4 ? -61.636 -9.364 -9.449 1.00 194.00 ? 31 PRO A CA 1 ATOM 26 C C . PRO A 1 4 ? -61.138 -8.593 -10.673 1.00 187.95 ? 31 PRO A C 1 ATOM 27 O O . PRO A 1 4 ? -61.839 -7.720 -11.187 1.00 185.81 ? 31 PRO A O 1 ATOM 28 C CB . PRO A 1 4 ? -62.634 -10.456 -9.868 1.00 184.59 ? 31 PRO A CB 1 ATOM 29 C CG . PRO A 1 4 ? -63.733 -10.409 -8.842 1.00 181.70 ? 31 PRO A CG 1 ATOM 30 C CD . PRO A 1 4 ? -63.813 -8.982 -8.408 1.00 188.88 ? 31 PRO A CD 1 ATOM 31 N N . ARG A 1 5 ? -59.929 -8.919 -11.125 1.00 182.53 ? 32 ARG A N 1 ATOM 32 C CA . ARG A 1 5 ? -59.354 -8.315 -12.326 1.00 180.48 ? 32 ARG A CA 1 ATOM 33 C C . ARG A 1 5 ? -58.592 -9.330 -13.186 1.00 180.87 ? 32 ARG A C 1 ATOM 34 O O . ARG A 1 5 ? -57.902 -10.204 -12.663 1.00 181.39 ? 32 ARG A O 1 ATOM 35 C CB . ARG A 1 5 ? -58.427 -7.158 -11.936 1.00 172.87 ? 32 ARG A CB 1 ATOM 36 C CG . ARG A 1 5 ? -57.475 -7.480 -10.791 1.00 163.91 ? 32 ARG A CG 1 ATOM 37 C CD . ARG A 1 5 ? -56.496 -6.345 -10.529 1.00 155.57 ? 32 ARG A CD 1 ATOM 38 N NE . ARG A 1 5 ? -55.626 -6.094 -11.676 1.00 156.39 ? 32 ARG A NE 1 ATOM 39 C CZ . ARG A 1 5 ? -54.457 -6.695 -11.877 1.00 166.38 ? 32 ARG A CZ 1 ATOM 40 N NH1 . ARG A 1 5 ? -54.013 -7.593 -11.009 1.00 170.26 ? 32 ARG A NH1 1 ATOM 41 N NH2 . ARG A 1 5 ? -53.734 -6.398 -12.948 1.00 166.32 ? 32 ARG A NH2 1 ATOM 42 N N . PHE A 1 6 ? -58.726 -9.209 -14.505 1.00 175.88 ? 33 PHE A N 1 ATOM 43 C CA . PHE A 1 6 ? -58.198 -10.205 -15.438 1.00 163.74 ? 33 PHE A CA 1 ATOM 44 C C . PHE A 1 6 ? -56.679 -10.163 -15.592 1.00 158.40 ? 33 PHE A C 1 ATOM 45 O O . PHE A 1 6 ? -56.091 -9.108 -15.839 1.00 160.95 ? 33 PHE A O 1 ATOM 46 C CB . PHE A 1 6 ? -58.851 -10.060 -16.814 1.00 156.99 ? 33 PHE A CB 1 ATOM 47 C CG . PHE A 1 6 ? -60.259 -10.574 -16.871 1.00 157.91 ? 33 PHE A CG 1 ATOM 48 C CD1 . PHE A 1 6 ? -60.581 -11.797 -16.306 1.00 154.18 ? 33 PHE A CD1 1 ATOM 49 C CD2 . PHE A 1 6 ? -61.251 -9.858 -17.517 1.00 159.47 ? 33 PHE A CD2 1 ATOM 50 C CE1 . PHE A 1 6 ? -61.871 -12.284 -16.361 1.00 158.47 ? 33 PHE A CE1 1 ATOM 51 C CE2 . PHE A 1 6 ? -62.543 -10.342 -17.580 1.00 163.79 ? 33 PHE A CE2 1 ATOM 52 C CZ . PHE A 1 6 ? -62.854 -11.556 -17.000 1.00 165.44 ? 33 PHE A CZ 1 ATOM 53 N N . THR A 1 7 ? -56.054 -11.326 -15.437 1.00 149.18 ? 34 THR A N 1 ATOM 54 C CA . THR A 1 7 ? -54.650 -11.504 -15.783 1.00 141.09 ? 34 THR A CA 1 ATOM 55 C C . THR A 1 7 ? -54.518 -12.063 -17.196 1.00 136.48 ? 34 THR A C 1 ATOM 56 O O . THR A 1 7 ? -53.553 -11.772 -17.901 1.00 137.48 ? 34 THR A O 1 ATOM 57 C CB . THR A 1 7 ? -53.938 -12.457 -14.798 1.00 137.37 ? 34 THR A CB 1 ATOM 58 O OG1 . THR A 1 7 ? -54.438 -13.790 -14.970 1.00 138.01 ? 34 THR A OG1 1 ATOM 59 C CG2 . THR A 1 7 ? -54.162 -12.013 -13.361 1.00 140.27 ? 34 THR A CG2 1 ATOM 60 N N . ARG A 1 8 ? -55.507 -12.849 -17.615 1.00 128.99 ? 35 ARG A N 1 ATOM 61 C CA . ARG A 1 8 ? -55.536 -13.375 -18.975 1.00 120.42 ? 35 ARG A CA 1 ATOM 62 C C . ARG A 1 8 ? -56.950 -13.451 -19.540 1.00 115.81 ? 35 ARG A C 1 ATOM 63 O O . ARG A 1 8 ? -57.812 -14.122 -18.973 1.00 117.16 ? 35 ARG A O 1 ATOM 64 C CB . ARG A 1 8 ? -54.912 -14.772 -19.003 1.00 124.21 ? 35 ARG A CB 1 ATOM 65 C CG . ARG A 1 8 ? -54.903 -15.434 -20.367 1.00 127.81 ? 35 ARG A CG 1 ATOM 66 C CD . ARG A 1 8 ? -53.984 -16.641 -20.367 1.00 130.51 ? 35 ARG A CD 1 ATOM 67 N NE . ARG A 1 8 ? -52.805 -16.449 -19.526 1.00 135.69 ? 35 ARG A NE 1 ATOM 68 C CZ . ARG A 1 8 ? -51.824 -17.337 -19.405 1.00 137.28 ? 35 ARG A CZ 1 ATOM 69 N NH1 . ARG A 1 8 ? -51.887 -18.486 -20.063 1.00 127.40 ? 35 ARG A NH1 1 ATOM 70 N NH2 . ARG A 1 8 ? -50.781 -17.076 -18.627 1.00 132.45 ? 35 ARG A NH2 1 ATOM 71 N N . THR A 1 9 ? -57.185 -12.774 -20.662 1.00 116.22 ? 36 THR A N 1 ATOM 72 C CA . THR A 1 9 ? -58.511 -12.775 -21.267 1.00 118.02 ? 36 THR A CA 1 ATOM 73 C C . THR A 1 9 ? -58.527 -13.745 -22.445 1.00 115.12 ? 36 THR A C 1 ATOM 74 O O . THR A 1 9 ? -57.526 -13.888 -23.145 1.00 123.70 ? 36 THR A O 1 ATOM 75 C CB . THR A 1 9 ? -58.924 -11.358 -21.751 1.00 116.53 ? 36 THR A CB 1 ATOM 76 O OG1 . THR A 1 9 ? -58.371 -11.101 -23.049 1.00 102.85 ? 36 THR A OG1 1 ATOM 77 C CG2 . THR A 1 9 ? -58.434 -10.290 -20.784 1.00 124.22 ? 36 THR A CG2 1 ATOM 78 N N . PRO A 1 10 ? -59.657 -14.436 -22.656 1.00 105.91 ? 37 PRO A N 1 ATOM 79 C CA . PRO A 1 10 ? -59.744 -15.338 -23.807 1.00 107.77 ? 37 PRO A CA 1 ATOM 80 C C . PRO A 1 10 ? -59.725 -14.562 -25.122 1.00 119.01 ? 37 PRO A C 1 ATOM 81 O O . PRO A 1 10 ? -60.273 -13.460 -25.176 1.00 119.90 ? 37 PRO A O 1 ATOM 82 C CB . PRO A 1 10 ? -61.082 -16.050 -23.587 1.00 105.35 ? 37 PRO A CB 1 ATOM 83 C CG . PRO A 1 10 ? -61.888 -15.077 -22.803 1.00 111.03 ? 37 PRO A CG 1 ATOM 84 C CD . PRO A 1 10 ? -60.907 -14.411 -21.878 1.00 111.01 ? 37 PRO A CD 1 ATOM 85 N N . VAL A 1 11 ? -59.114 -15.118 -26.164 1.00 125.06 ? 38 VAL A N 1 ATOM 86 C CA . VAL A 1 11 ? -59.201 -14.509 -27.485 1.00 124.13 ? 38 VAL A CA 1 ATOM 87 C C . VAL A 1 11 ? -60.096 -15.373 -28.364 1.00 128.27 ? 38 VAL A C 1 ATOM 88 O O . VAL A 1 11 ? -60.194 -16.580 -28.149 1.00 126.92 ? 38 VAL A O 1 ATOM 89 C CB . VAL A 1 11 ? -57.811 -14.338 -28.137 1.00 122.94 ? 38 VAL A CB 1 ATOM 90 C CG1 . VAL A 1 11 ? -57.282 -12.925 -27.900 1.00 117.15 ? 38 VAL A CG1 1 ATOM 91 C CG2 . VAL A 1 11 ? -56.835 -15.376 -27.602 1.00 124.85 ? 38 VAL A CG2 1 ATOM 92 N N . ASP A 1 12 ? -60.769 -14.747 -29.327 1.00 133.24 ? 39 ASP A N 1 ATOM 93 C CA . ASP A 1 12 ? -61.563 -15.459 -30.330 1.00 131.88 ? 39 ASP A CA 1 ATOM 94 C C . ASP A 1 12 ? -60.824 -16.648 -30.963 1.00 118.93 ? 39 ASP A C 1 ATOM 95 O O . ASP A 1 12 ? -59.597 -16.641 -31.061 1.00 116.76 ? 39 ASP A O 1 ATOM 96 C CB . ASP A 1 12 ? -62.000 -14.478 -31.423 1.00 135.26 ? 39 ASP A CB 1 ATOM 97 C CG . ASP A 1 12 ? -63.120 -13.555 -30.968 1.00 141.08 ? 39 ASP A CG 1 ATOM 98 O OD1 . ASP A 1 12 ? -63.761 -13.850 -29.939 1.00 145.83 ? 39 ASP A OD1 1 ATOM 99 O OD2 . ASP A 1 12 ? -63.354 -12.526 -31.636 1.00 140.02 ? 39 ASP A OD2 1 ATOM 100 N N . GLN A 1 13 ? -61.570 -17.659 -31.403 1.00 113.39 ? 40 GLN A N 1 ATOM 101 C CA . GLN A 1 13 ? -60.969 -18.817 -32.072 1.00 113.92 ? 40 GLN A CA 1 ATOM 102 C C . GLN A 1 13 ? -61.808 -19.305 -33.253 1.00 118.96 ? 40 GLN A C 1 ATOM 103 O O . GLN A 1 13 ? -63.013 -19.068 -33.309 1.00 123.30 ? 40 GLN A O 1 ATOM 104 C CB . GLN A 1 13 ? -60.702 -19.963 -31.099 1.00 116.76 ? 40 GLN A CB 1 ATOM 105 C CG . GLN A 1 13 ? -59.245 -19.991 -30.656 1.00 118.17 ? 40 GLN A CG 1 ATOM 106 C CD . GLN A 1 13 ? -58.824 -21.320 -30.072 1.00 113.72 ? 40 GLN A CD 1 ATOM 107 O OE1 . GLN A 1 13 ? -59.598 -21.987 -29.389 1.00 116.46 ? 40 GLN A OE1 1 ATOM 108 N NE2 . GLN A 1 13 ? -57.585 -21.717 -30.346 1.00 103.76 ? 40 GLN A NE2 1 ATOM 109 N N . THR A 1 14 ? -61.152 -19.990 -34.185 1.00 121.61 ? 41 THR A N 1 ATOM 110 C CA . THR A 1 14 ? -61.809 -20.605 -35.338 1.00 127.09 ? 41 THR A CA 1 ATOM 111 C C . THR A 1 14 ? -61.247 -22.007 -35.612 1.00 126.49 ? 41 THR A C 1 ATOM 112 O O . THR A 1 14 ? -60.208 -22.143 -36.251 1.00 128.10 ? 41 THR A O 1 ATOM 113 C CB . THR A 1 14 ? -61.663 -19.730 -36.605 1.00 129.26 ? 41 THR A CB 1 ATOM 114 O OG1 . THR A 1 14 ? -62.236 -18.439 -36.365 1.00 125.91 ? 41 THR A OG1 1 ATOM 115 C CG2 . THR A 1 14 ? -62.370 -20.373 -37.789 1.00 124.43 ? 41 THR A CG2 1 ATOM 116 N N . GLY A 1 15 ? -61.924 -23.046 -35.123 1.00 131.35 ? 42 GLY A N 1 ATOM 117 C CA . GLY A 1 15 ? -61.417 -24.405 -35.256 1.00 129.30 ? 42 GLY A CA 1 ATOM 118 C C . GLY A 1 15 ? -62.065 -25.218 -36.368 1.00 125.20 ? 42 GLY A C 1 ATOM 119 O O . GLY A 1 15 ? -62.845 -24.681 -37.153 1.00 128.61 ? 42 GLY A O 1 ATOM 120 N N . VAL A 1 16 ? -61.741 -26.511 -36.434 1.00 120.34 ? 43 VAL A N 1 ATOM 121 C CA . VAL A 1 16 ? -62.215 -27.385 -37.514 1.00 124.51 ? 43 VAL A CA 1 ATOM 122 C C . VAL A 1 16 ? -62.961 -28.646 -37.055 1.00 126.50 ? 43 VAL A C 1 ATOM 123 O O . VAL A 1 16 ? -62.566 -29.282 -36.076 1.00 123.58 ? 43 VAL A O 1 ATOM 124 C CB . VAL A 1 16 ? -61.006 -27.817 -38.399 1.00 120.92 ? 43 VAL A CB 1 ATOM 125 C CG1 . VAL A 1 16 ? -61.259 -29.145 -39.106 1.00 125.74 ? 43 VAL A CG1 1 ATOM 126 C CG2 . VAL A 1 16 ? -60.662 -26.727 -39.396 1.00 125.66 ? 43 VAL A CG2 1 ATOM 127 N N . SER A 1 17 ? -64.056 -28.971 -37.752 1.00 129.75 ? 44 SER A N 1 ATOM 128 C CA . SER A 1 17 ? -64.985 -30.036 -37.352 1.00 126.69 ? 44 SER A CA 1 ATOM 129 C C . SER A 1 17 ? -64.270 -31.342 -37.034 1.00 131.15 ? 44 SER A C 1 ATOM 130 O O . SER A 1 17 ? -63.415 -31.802 -37.793 1.00 133.12 ? 44 SER A O 1 ATOM 131 C CB . SER A 1 17 ? -66.023 -30.290 -38.450 1.00 125.10 ? 44 SER A CB 1 ATOM 132 O OG . SER A 1 17 ? -66.991 -31.241 -38.043 1.00 125.80 ? 44 SER A OG 1 ATOM 133 N N . GLY A 1 18 ? -64.624 -31.926 -35.900 1.00 134.35 ? 45 GLY A N 1 ATOM 134 C CA . GLY A 1 18 ? -63.963 -33.116 -35.415 1.00 134.37 ? 45 GLY A CA 1 ATOM 135 C C . GLY A 1 18 ? -62.561 -32.760 -34.971 1.00 134.36 ? 45 GLY A C 1 ATOM 136 O O . GLY A 1 18 ? -61.628 -33.544 -35.155 1.00 142.10 ? 45 GLY A O 1 ATOM 137 N N . GLY A 1 19 ? -62.398 -31.573 -34.394 1.00 129.78 ? 46 GLY A N 1 ATOM 138 C CA . GLY A 1 19 ? -61.100 -31.182 -33.879 1.00 132.90 ? 46 GLY A CA 1 ATOM 139 C C . GLY A 1 19 ? -61.195 -30.609 -32.479 1.00 135.89 ? 46 GLY A C 1 ATOM 140 O O . GLY A 1 19 ? -62.132 -30.914 -31.743 1.00 134.26 ? 46 GLY A O 1 ATOM 141 N N . VAL A 1 20 ? -60.233 -29.767 -32.111 1.00 137.43 ? 47 VAL A N 1 ATOM 142 C CA . VAL A 1 20 ? -60.216 -29.178 -30.776 1.00 125.73 ? 47 VAL A CA 1 ATOM 143 C C . VAL A 1 20 ? -60.357 -27.645 -30.799 1.00 121.15 ? 47 VAL A C 1 ATOM 144 O O . VAL A 1 20 ? -59.883 -26.991 -31.730 1.00 112.90 ? 47 VAL A O 1 ATOM 145 C CB . VAL A 1 20 ? -58.915 -29.573 -30.032 1.00 110.15 ? 47 VAL A CB 1 ATOM 146 C CG1 . VAL A 1 20 ? -59.008 -29.221 -28.563 1.00 112.71 ? 47 VAL A CG1 1 ATOM 147 C CG2 . VAL A 1 20 ? -58.658 -31.062 -30.177 1.00 111.65 ? 47 VAL A CG2 1 ATOM 148 N N . ALA A 1 21 ? -61.013 -27.079 -29.786 1.00 124.28 ? 48 ALA A N 1 ATOM 149 C CA . ALA A 1 21 ? -60.918 -25.645 -29.507 1.00 122.77 ? 48 ALA A CA 1 ATOM 150 C C . ALA A 1 21 ? -60.667 -25.450 -28.010 1.00 126.54 ? 48 ALA A C 1 ATOM 151 O O . ALA A 1 21 ? -61.327 -26.087 -27.188 1.00 123.09 ? 48 ALA A O 1 ATOM 152 C CB . ALA A 1 21 ? -62.184 -24.921 -29.943 1.00 118.31 ? 48 ALA A CB 1 ATOM 153 N N . SER A 1 22 ? -59.726 -24.580 -27.646 1.00 124.78 ? 49 SER A N 1 ATOM 154 C CA . SER A 1 22 ? -59.530 -24.225 -26.239 1.00 119.13 ? 49 SER A CA 1 ATOM 155 C C . SER A 1 22 ? -59.693 -22.732 -25.945 1.00 124.45 ? 49 SER A C 1 ATOM 156 O O . SER A 1 22 ? -59.205 -21.890 -26.694 1.00 127.46 ? 49 SER A O 1 ATOM 157 C CB . SER A 1 22 ? -58.150 -24.691 -25.767 1.00 114.10 ? 49 SER A CB 1 ATOM 158 O OG . SER A 1 22 ? -57.119 -24.173 -26.588 1.00 115.77 ? 49 SER A OG 1 ATOM 159 N N . PHE A 1 23 ? -60.363 -22.412 -24.841 1.00 129.71 ? 50 PHE A N 1 ATOM 160 C CA . PHE A 1 23 ? -60.500 -21.027 -24.385 1.00 132.80 ? 50 PHE A CA 1 ATOM 161 C C . PHE A 1 23 ? -59.962 -20.836 -22.964 1.00 129.94 ? 50 PHE A C 1 ATOM 162 O O . PHE A 1 23 ? -60.179 -21.681 -22.096 1.00 129.17 ? 50 PHE A O 1 ATOM 163 C CB . PHE A 1 23 ? -61.955 -20.571 -24.489 1.00 130.24 ? 50 PHE A CB 1 ATOM 164 C CG . PHE A 1 23 ? -62.383 -20.254 -25.895 1.00 125.20 ? 50 PHE A CG 1 ATOM 165 C CD1 . PHE A 1 23 ? -61.914 -19.112 -26.526 1.00 127.91 ? 50 PHE A CD1 1 ATOM 166 C CD2 . PHE A 1 23 ? -63.228 -21.099 -26.595 1.00 123.71 ? 50 PHE A CD2 1 ATOM 167 C CE1 . PHE A 1 23 ? -62.293 -18.808 -27.818 1.00 129.45 ? 50 PHE A CE1 1 ATOM 168 C CE2 . PHE A 1 23 ? -63.609 -20.800 -27.894 1.00 129.97 ? 50 PHE A CE2 1 ATOM 169 C CZ . PHE A 1 23 ? -63.140 -19.651 -28.505 1.00 130.38 ? 50 PHE A CZ 1 ATOM 170 N N . ILE A 1 24 ? -59.264 -19.727 -22.727 1.00 123.48 ? 51 ILE A N 1 ATOM 171 C CA . ILE A 1 24 ? -58.605 -19.515 -21.441 1.00 124.54 ? 51 ILE A CA 1 ATOM 172 C C . ILE A 1 24 ? -59.110 -18.297 -20.664 1.00 123.66 ? 51 ILE A C 1 ATOM 173 O O . ILE A 1 24 ? -59.268 -17.212 -21.221 1.00 114.52 ? 51 ILE A O 1 ATOM 174 C CB . ILE A 1 24 ? -57.079 -19.340 -21.623 1.00 126.63 ? 51 ILE A CB 1 ATOM 175 C CG1 . ILE A 1 24 ? -56.483 -20.492 -22.433 1.00 122.24 ? 51 ILE A CG1 1 ATOM 176 C CG2 . ILE A 1 24 ? -56.388 -19.201 -20.272 1.00 127.57 ? 51 ILE A CG2 1 ATOM 177 C CD1 . ILE A 1 24 ? -55.134 -20.164 -23.047 1.00 129.52 ? 51 ILE A CD1 1 ATOM 178 N N . CYS A 1 25 ? -59.357 -18.490 -19.372 1.00 129.06 ? 52 CYS A N 1 ATOM 179 C CA . CYS A 1 25 ? -59.728 -17.394 -18.486 1.00 129.66 ? 52 CYS A CA 1 ATOM 180 C C . CYS A 1 25 ? -59.014 -17.555 -17.156 1.00 133.20 ? 52 CYS A C 1 ATOM 181 O O . CYS A 1 25 ? -59.278 -18.493 -16.404 1.00 130.26 ? 52 CYS A O 1 ATOM 182 C CB . CYS A 1 25 ? -61.240 -17.334 -18.264 1.00 134.97 ? 52 CYS A CB 1 ATOM 183 S SG . CYS A 1 25 ? -61.903 -15.656 -18.104 1.00 138.84 ? 52 CYS A SG 1 ATOM 184 N N . GLN A 1 26 ? -58.108 -16.630 -16.870 1.00 139.52 ? 53 GLN A N 1 ATOM 185 C CA . GLN A 1 26 ? -57.389 -16.626 -15.607 1.00 146.72 ? 53 GLN A CA 1 ATOM 186 C C . GLN A 1 26 ? -57.626 -15.280 -14.944 1.00 152.57 ? 53 GLN A C 1 ATOM 187 O O . GLN A 1 26 ? -57.565 -14.242 -15.602 1.00 150.16 ? 53 GLN A O 1 ATOM 188 C CB . GLN A 1 26 ? -55.895 -16.888 -15.812 1.00 139.09 ? 53 GLN A CB 1 ATOM 189 C CG . GLN A 1 26 ? -55.384 -18.111 -15.066 1.00 138.00 ? 53 GLN A CG 1 ATOM 190 C CD . GLN A 1 26 ? -53.911 -18.372 -15.303 1.00 139.80 ? 53 GLN A CD 1 ATOM 191 O OE1 . GLN A 1 26 ? -53.498 -18.701 -16.415 1.00 145.72 ? 53 GLN A OE1 1 ATOM 192 N NE2 . GLN A 1 26 ? -53.110 -18.240 -14.251 1.00 136.89 ? 53 GLN A NE2 1 ATOM 193 N N . ALA A 1 27 ? -57.898 -15.290 -13.644 1.00 154.11 ? 54 ALA A N 1 ATOM 194 C CA . ALA A 1 27 ? -58.215 -14.050 -12.952 1.00 161.54 ? 54 ALA A CA 1 ATOM 195 C C . ALA A 1 27 ? -57.699 -14.015 -11.519 1.00 162.64 ? 54 ALA A C 1 ATOM 196 O O . ALA A 1 27 ? -57.485 -15.053 -10.892 1.00 154.03 ? 54 ALA A O 1 ATOM 197 C CB . ALA A 1 27 ? -59.720 -13.820 -12.970 1.00 166.69 ? 54 ALA A CB 1 ATOM 198 N N . THR A 1 28 ? -57.508 -12.798 -11.019 1.00 171.89 ? 55 THR A N 1 ATOM 199 C CA . THR A 1 28 ? -56.999 -12.549 -9.674 1.00 179.88 ? 55 THR A CA 1 ATOM 200 C C . THR A 1 28 ? -57.987 -11.664 -8.919 1.00 181.50 ? 55 THR A C 1 ATOM 201 O O . THR A 1 28 ? -58.651 -10.813 -9.513 1.00 181.43 ? 55 THR A O 1 ATOM 202 C CB . THR A 1 28 ? -55.596 -11.894 -9.690 1.00 179.09 ? 55 THR A CB 1 ATOM 203 O OG1 . THR A 1 28 ? -55.117 -11.753 -8.346 1.00 183.32 ? 55 THR A OG1 1 ATOM 204 C CG2 . THR A 1 28 ? -55.639 -10.524 -10.345 1.00 171.99 ? 55 THR A CG2 1 ATOM 205 N N . GLY A 1 29 ? -58.104 -11.884 -7.615 1.00 180.18 ? 56 GLY A N 1 ATOM 206 C CA . GLY A 1 29 ? -58.950 -11.051 -6.780 1.00 178.15 ? 56 GLY A CA 1 ATOM 207 C C . GLY A 1 29 ? -58.954 -11.513 -5.337 1.00 174.60 ? 56 GLY A C 1 ATOM 208 O O . GLY A 1 29 ? -58.531 -12.630 -5.036 1.00 173.30 ? 56 GLY A O 1 ATOM 209 N N . ASP A 1 30 ? -59.406 -10.641 -4.440 1.00 173.19 ? 57 ASP A N 1 ATOM 210 C CA . ASP A 1 30 ? -59.537 -10.991 -3.029 1.00 172.38 ? 57 ASP A CA 1 ATOM 211 C C . ASP A 1 30 ? -60.989 -10.894 -2.552 1.00 171.09 ? 57 ASP A C 1 ATOM 212 O O . ASP A 1 30 ? -61.575 -9.811 -2.560 1.00 164.93 ? 57 ASP A O 1 ATOM 213 C CB . ASP A 1 30 ? -58.646 -10.082 -2.180 1.00 166.58 ? 57 ASP A CB 1 ATOM 214 C CG . ASP A 1 30 ? -58.551 -10.536 -0.740 1.00 162.49 ? 57 ASP A CG 1 ATOM 215 O OD1 . ASP A 1 30 ? -58.601 -11.759 -0.491 1.00 162.97 ? 57 ASP A OD1 1 ATOM 216 O OD2 . ASP A 1 30 ? -58.427 -9.665 0.146 1.00 163.61 ? 57 ASP A OD2 1 ATOM 217 N N . PRO A 1 31 ? -61.578 -12.033 -2.137 1.00 176.57 ? 58 PRO A N 1 ATOM 218 C CA . PRO A 1 31 ? -60.946 -13.357 -2.080 1.00 175.57 ? 58 PRO A CA 1 ATOM 219 C C . PRO A 1 31 ? -60.845 -13.976 -3.469 1.00 178.45 ? 58 PRO A C 1 ATOM 220 O O . PRO A 1 31 ? -61.203 -13.312 -4.441 1.00 187.33 ? 58 PRO A O 1 ATOM 221 C CB . PRO A 1 31 ? -61.897 -14.162 -1.194 1.00 166.48 ? 58 PRO A CB 1 ATOM 222 C CG . PRO A 1 31 ? -63.224 -13.534 -1.421 1.00 168.08 ? 58 PRO A CG 1 ATOM 223 C CD . PRO A 1 31 ? -62.965 -12.068 -1.640 1.00 173.29 ? 58 PRO A CD 1 ATOM 224 N N . ARG A 1 32 ? -60.400 -15.224 -3.566 1.00 169.03 ? 59 ARG A N 1 ATOM 225 C CA . ARG A 1 32 ? -60.186 -15.821 -4.875 1.00 162.71 ? 59 ARG A CA 1 ATOM 226 C C . ARG A 1 32 ? -61.512 -15.987 -5.600 1.00 165.41 ? 59 ARG A C 1 ATOM 227 O O . ARG A 1 32 ? -62.411 -16.673 -5.117 1.00 166.63 ? 59 ARG A O 1 ATOM 228 C CB . ARG A 1 32 ? -59.481 -17.173 -4.765 1.00 149.05 ? 59 ARG A CB 1 ATOM 229 C CG . ARG A 1 32 ? -57.998 -17.095 -4.463 1.00 143.77 ? 59 ARG A CG 1 ATOM 230 C CD . ARG A 1 32 ? -57.433 -18.488 -4.236 1.00 150.82 ? 59 ARG A CD 1 ATOM 231 N NE . ARG A 1 32 ? -56.028 -18.473 -3.839 1.00 153.43 ? 59 ARG A NE 1 ATOM 232 C CZ . ARG A 1 32 ? -55.297 -19.566 -3.645 1.00 143.49 ? 59 ARG A CZ 1 ATOM 233 N NH1 . ARG A 1 32 ? -55.836 -20.765 -3.816 1.00 135.49 ? 59 ARG A NH1 1 ATOM 234 N NH2 . ARG A 1 32 ? -54.026 -19.461 -3.279 1.00 134.95 ? 59 ARG A NH2 1 ATOM 235 N N . PRO A 1 33 ? -61.633 -15.341 -6.768 1.00 160.68 ? 60 PRO A N 1 ATOM 236 C CA . PRO A 1 33 ? -62.828 -15.392 -7.612 1.00 152.87 ? 60 PRO A CA 1 ATOM 237 C C . PRO A 1 33 ? -63.104 -16.822 -8.047 1.00 153.07 ? 60 PRO A C 1 ATOM 238 O O . PRO A 1 33 ? -62.168 -17.558 -8.355 1.00 153.75 ? 60 PRO A O 1 ATOM 239 C CB . PRO A 1 33 ? -62.462 -14.503 -8.805 1.00 149.54 ? 60 PRO A CB 1 ATOM 240 C CG . PRO A 1 33 ? -61.379 -13.621 -8.301 1.00 154.28 ? 60 PRO A CG 1 ATOM 241 C CD . PRO A 1 33 ? -60.598 -14.469 -7.350 1.00 161.85 ? 60 PRO A CD 1 ATOM 242 N N . LYS A 1 34 ? -64.373 -17.209 -8.078 1.00 156.66 ? 61 LYS A N 1 ATOM 243 C CA . LYS A 1 34 ? -64.736 -18.445 -8.752 1.00 152.75 ? 61 LYS A CA 1 ATOM 244 C C . LYS A 1 34 ? -64.971 -18.098 -10.211 1.00 148.19 ? 61 LYS A C 1 ATOM 245 O O . LYS A 1 34 ? -65.425 -17.002 -10.535 1.00 158.21 ? 61 LYS A O 1 ATOM 246 C CB . LYS A 1 34 ? -65.976 -19.079 -8.110 1.00 150.88 ? 61 LYS A CB 1 ATOM 247 C CG . LYS A 1 34 ? -67.272 -18.312 -8.339 1.00 148.51 ? 61 LYS A CG 1 ATOM 248 C CD . LYS A 1 34 ? -68.355 -19.215 -8.901 1.00 140.62 ? 61 LYS A CD 1 ATOM 249 C CE . LYS A 1 34 ? -68.995 -20.049 -7.803 1.00 131.32 ? 61 LYS A CE 1 ATOM 250 N NZ . LYS A 1 34 ? -70.142 -20.848 -8.314 1.00 121.79 ? 61 LYS A NZ 1 ATOM 251 N N . ILE A 1 35 ? -64.651 -19.040 -11.090 1.00 133.86 ? 62 ILE A N 1 ATOM 252 C CA . ILE A 1 35 ? -64.863 -18.851 -12.517 1.00 133.30 ? 62 ILE A CA 1 ATOM 253 C C . ILE A 1 35 ? -65.948 -19.750 -13.106 1.00 129.70 ? 62 ILE A C 1 ATOM 254 O O . ILE A 1 35 ? -66.060 -20.927 -12.767 1.00 131.82 ? 62 ILE A O 1 ATOM 255 C CB . ILE A 1 35 ? -63.521 -19.070 -13.281 1.00 141.27 ? 62 ILE A CB 1 ATOM 256 C CG1 . ILE A 1 35 ? -63.615 -18.549 -14.712 1.00 145.00 ? 62 ILE A CG1 1 ATOM 257 C CG2 . ILE A 1 35 ? -63.064 -20.527 -13.220 1.00 141.98 ? 62 ILE A CG2 1 ATOM 258 C CD1 . ILE A 1 35 ? -63.796 -17.065 -14.771 1.00 141.05 ? 62 ILE A CD1 1 ATOM 259 N N . VAL A 1 36 ? -66.780 -19.158 -13.960 1.00 134.62 ? 63 VAL A N 1 ATOM 260 C CA . VAL A 1 36 ? -67.886 -19.871 -14.585 1.00 146.35 ? 63 VAL A CA 1 ATOM 261 C C . VAL A 1 36 ? -67.878 -19.600 -16.097 1.00 151.52 ? 63 VAL A C 1 ATOM 262 O O . VAL A 1 36 ? -67.645 -18.471 -16.532 1.00 154.56 ? 63 VAL A O 1 ATOM 263 C CB . VAL A 1 36 ? -69.240 -19.452 -13.947 1.00 146.99 ? 63 VAL A CB 1 ATOM 264 C CG1 . VAL A 1 36 ? -70.406 -19.802 -14.844 1.00 149.21 ? 63 VAL A CG1 1 ATOM 265 C CG2 . VAL A 1 36 ? -69.412 -20.113 -12.583 1.00 137.01 ? 63 VAL A CG2 1 ATOM 266 N N . TRP A 1 37 ? -68.127 -20.644 -16.887 1.00 147.79 ? 64 TRP A N 1 ATOM 267 C CA . TRP A 1 37 ? -68.190 -20.549 -18.348 1.00 145.11 ? 64 TRP A CA 1 ATOM 268 C C . TRP A 1 37 ? -69.638 -20.530 -18.838 1.00 142.52 ? 64 TRP A C 1 ATOM 269 O O . TRP A 1 37 ? -70.398 -21.469 -18.595 1.00 143.44 ? 64 TRP A O 1 ATOM 270 C CB . TRP A 1 37 ? -67.411 -21.703 -18.985 1.00 147.07 ? 64 TRP A CB 1 ATOM 271 C CG . TRP A 1 37 ? -65.935 -21.642 -18.696 1.00 145.73 ? 64 TRP A CG 1 ATOM 272 C CD1 . TRP A 1 37 ? -65.256 -22.309 -17.714 1.00 144.75 ? 64 TRP A CD1 1 ATOM 273 C CD2 . TRP A 1 37 ? -64.956 -20.880 -19.413 1.00 140.27 ? 64 TRP A CD2 1 ATOM 274 N NE1 . TRP A 1 37 ? -63.918 -21.998 -17.769 1.00 140.48 ? 64 TRP A NE1 1 ATOM 275 C CE2 . TRP A 1 37 ? -63.707 -21.125 -18.804 1.00 138.68 ? 64 TRP A CE2 1 ATOM 276 C CE3 . TRP A 1 37 ? -65.014 -20.011 -20.509 1.00 130.92 ? 64 TRP A CE3 1 ATOM 277 C CZ2 . TRP A 1 37 ? -62.528 -20.533 -19.256 1.00 133.75 ? 64 TRP A CZ2 1 ATOM 278 C CZ3 . TRP A 1 37 ? -63.845 -19.426 -20.955 1.00 125.17 ? 64 TRP A CZ3 1 ATOM 279 C CH2 . TRP A 1 37 ? -62.619 -19.691 -20.331 1.00 130.69 ? 64 TRP A CH2 1 ATOM 280 N N . ASN A 1 38 ? -70.007 -19.453 -19.529 1.00 141.14 ? 65 ASN A N 1 ATOM 281 C CA . ASN A 1 38 ? -71.364 -19.279 -20.048 1.00 147.85 ? 65 ASN A CA 1 ATOM 282 C C . ASN A 1 38 ? -71.580 -19.256 -21.570 1.00 148.81 ? 65 ASN A C 1 ATOM 283 O O . ASN A 1 38 ? -70.787 -18.684 -22.316 1.00 145.77 ? 65 ASN A O 1 ATOM 284 C CB . ASN A 1 38 ? -71.932 -17.970 -19.489 1.00 153.03 ? 65 ASN A CB 1 ATOM 285 C CG . ASN A 1 38 ? -72.020 -17.966 -17.976 1.00 152.89 ? 65 ASN A CG 1 ATOM 286 O OD1 . ASN A 1 38 ? -72.062 -19.015 -17.343 1.00 153.51 ? 65 ASN A OD1 1 ATOM 287 N ND2 . ASN A 1 38 ? -72.043 -16.775 -17.388 1.00 156.76 ? 65 ASN A ND2 1 ATOM 288 N N . LYS A 1 39 ? -72.666 -19.893 -22.009 1.00 150.20 ? 66 LYS A N 1 ATOM 289 C CA . LYS A 1 39 ? -73.230 -19.674 -23.344 1.00 151.64 ? 66 LYS A CA 1 ATOM 290 C C . LYS A 1 39 ? -74.546 -18.949 -23.109 1.00 155.00 ? 66 LYS A C 1 ATOM 291 O O . LYS A 1 39 ? -75.484 -19.513 -22.544 1.00 153.91 ? 66 LYS A O 1 ATOM 292 C CB . LYS A 1 39 ? -73.463 -20.974 -24.118 1.00 143.59 ? 66 LYS A CB 1 ATOM 293 C CG . LYS A 1 39 ? -74.158 -20.798 -25.465 1.00 139.19 ? 66 LYS A CG 1 ATOM 294 C CD . LYS A 1 39 ? -73.827 -21.932 -26.417 1.00 139.52 ? 66 LYS A CD 1 ATOM 295 C CE . LYS A 1 39 ? -74.895 -23.014 -26.378 1.00 142.74 ? 66 LYS A CE 1 ATOM 296 N NZ . LYS A 1 39 ? -74.512 -24.197 -27.197 1.00 136.75 ? 66 LYS A NZ 1 ATOM 297 N N . LYS A 1 40 ? -74.602 -17.706 -23.572 1.00 159.63 ? 67 LYS A N 1 ATOM 298 C CA . LYS A 1 40 ? -75.721 -16.801 -23.324 1.00 162.28 ? 67 LYS A CA 1 ATOM 299 C C . LYS A 1 40 ? -76.108 -16.739 -21.841 1.00 173.65 ? 67 LYS A C 1 ATOM 300 O O . LYS A 1 40 ? -77.153 -17.254 -21.443 1.00 176.83 ? 67 LYS A O 1 ATOM 301 C CB . LYS A 1 40 ? -76.941 -17.209 -24.156 1.00 162.90 ? 67 LYS A CB 1 ATOM 302 C CG . LYS A 1 40 ? -76.825 -16.924 -25.646 1.00 170.12 ? 67 LYS A CG 1 ATOM 303 C CD . LYS A 1 40 ? -78.199 -16.898 -26.305 1.00 174.22 ? 67 LYS A CD 1 ATOM 304 C CE . LYS A 1 40 ? -78.100 -16.790 -27.818 1.00 171.85 ? 67 LYS A CE 1 ATOM 305 N NZ . LYS A 1 40 ? -79.450 -16.744 -28.448 1.00 164.74 ? 67 LYS A NZ 1 ATOM 306 N N . GLY A 1 41 ? -75.261 -16.100 -21.035 1.00 178.45 ? 68 GLY A N 1 ATOM 307 C CA . GLY A 1 41 ? -75.481 -15.954 -19.602 1.00 174.06 ? 68 GLY A CA 1 ATOM 308 C C . GLY A 1 41 ? -75.647 -17.171 -18.697 1.00 170.22 ? 68 GLY A C 1 ATOM 309 O O . GLY A 1 41 ? -75.475 -17.066 -17.482 1.00 175.82 ? 68 GLY A O 1 ATOM 310 N N . LYS A 1 42 ? -75.968 -18.319 -19.283 1.00 166.26 ? 69 LYS A N 1 ATOM 311 C CA . LYS A 1 42 ? -76.249 -19.554 -18.543 1.00 158.91 ? 69 LYS A CA 1 ATOM 312 C C . LYS A 1 42 ? -75.042 -20.477 -18.381 1.00 152.34 ? 69 LYS A C 1 ATOM 313 O O . LYS A 1 42 ? -74.490 -20.958 -19.359 1.00 145.00 ? 69 LYS A O 1 ATOM 314 C CB . LYS A 1 42 ? -77.404 -20.297 -19.215 1.00 166.25 ? 69 LYS A CB 1 ATOM 315 C CG . LYS A 1 42 ? -78.748 -19.934 -18.607 1.00 168.86 ? 69 LYS A CG 1 ATOM 316 C CD . LYS A 1 42 ? -79.306 -18.667 -19.236 1.00 174.22 ? 69 LYS A CD 1 ATOM 317 C CE . LYS A 1 42 ? -80.663 -18.303 -18.658 1.00 174.35 ? 69 LYS A CE 1 ATOM 318 N NZ . LYS A 1 42 ? -81.172 -17.023 -19.227 1.00 179.29 ? 69 LYS A NZ 1 ATOM 319 N N . LYS A 1 43 ? -74.618 -20.673 -17.135 1.00 156.07 ? 70 LYS A N 1 ATOM 320 C CA . LYS A 1 43 ? -73.606 -21.672 -16.769 1.00 155.94 ? 70 LYS A CA 1 ATOM 321 C C . LYS A 1 43 ? -73.718 -23.040 -17.463 1.00 153.51 ? 70 LYS A C 1 ATOM 322 O O . LYS A 1 43 ? -74.280 -23.986 -16.912 1.00 155.92 ? 70 LYS A O 1 ATOM 323 C CB . LYS A 1 43 ? -73.632 -21.873 -15.240 1.00 145.49 ? 70 LYS A CB 1 ATOM 324 C CG . LYS A 1 43 ? -72.481 -22.697 -14.641 1.00 130.27 ? 70 LYS A CG 1 ATOM 325 C CD . LYS A 1 43 ? -72.967 -24.066 -14.164 1.00 120.32 ? 70 LYS A CD 1 ATOM 326 C CE . LYS A 1 43 ? -71.832 -24.946 -13.664 1.00 110.36 ? 70 LYS A CE 1 ATOM 327 N NZ . LYS A 1 43 ? -72.337 -26.282 -13.227 1.00 91.95 ? 70 LYS A NZ 1 ATOM 328 N N . VAL A 1 44 ? -73.217 -23.121 -18.698 1.00 147.60 ? 71 VAL A N 1 ATOM 329 C CA . VAL A 1 44 ? -73.351 -24.343 -19.497 1.00 147.89 ? 71 VAL A CA 1 ATOM 330 C C . VAL A 1 44 ? -72.413 -25.419 -18.969 1.00 148.35 ? 71 VAL A C 1 ATOM 331 O O . VAL A 1 44 ? -71.350 -25.153 -18.409 1.00 140.30 ? 71 VAL A O 1 ATOM 332 C CB . VAL A 1 44 ? -73.131 -24.134 -21.013 1.00 143.43 ? 71 VAL A CB 1 ATOM 333 C CG1 . VAL A 1 44 ? -73.786 -22.882 -21.477 1.00 139.06 ? 71 VAL A CG1 1 ATOM 334 C CG2 . VAL A 1 44 ? -71.656 -24.238 -21.403 1.00 141.20 ? 71 VAL A CG2 1 ATOM 335 N N . SER A 1 45 ? -72.864 -26.644 -19.163 1.00 150.46 ? 72 SER A N 1 ATOM 336 C CA . SER A 1 45 ? -72.178 -27.880 -18.835 1.00 144.94 ? 72 SER A CA 1 ATOM 337 C C . SER A 1 45 ? -72.640 -28.860 -19.892 1.00 138.33 ? 72 SER A C 1 ATOM 338 O O . SER A 1 45 ? -73.794 -28.814 -20.318 1.00 142.70 ? 72 SER A O 1 ATOM 339 C CB . SER A 1 45 ? -72.448 -28.380 -17.425 1.00 149.70 ? 72 SER A CB 1 ATOM 340 O OG . SER A 1 45 ? -71.575 -29.461 -17.133 1.00 148.12 ? 72 SER A OG 1 ATOM 341 N N . ASN A 1 46 ? -71.730 -29.685 -20.381 1.00 133.18 ? 73 ASN A N 1 ATOM 342 C CA . ASN A 1 46 ? -71.950 -30.480 -21.567 1.00 138.21 ? 73 ASN A CA 1 ATOM 343 C C . ASN A 1 46 ? -70.754 -31.390 -21.725 1.00 146.93 ? 73 ASN A C 1 ATOM 344 O O . ASN A 1 46 ? -69.614 -30.999 -21.543 1.00 150.96 ? 73 ASN A O 1 ATOM 345 C CB . ASN A 1 46 ? -72.105 -29.571 -22.798 1.00 134.46 ? 73 ASN A CB 1 ATOM 346 C CG . ASN A 1 46 ? -72.682 -30.290 -24.007 1.00 136.82 ? 73 ASN A CG 1 ATOM 347 O OD1 . ASN A 1 46 ? -72.389 -31.459 -24.254 1.00 139.72 ? 73 ASN A OD1 1 ATOM 348 N ND2 . ASN A 1 46 ? -73.500 -29.579 -24.778 1.00 128.65 ? 73 ASN A ND2 1 ATOM 349 N N . GLN A 1 47 ? -71.065 -32.645 -22.021 1.00 150.35 ? 74 GLN A N 1 ATOM 350 C CA . GLN A 1 47 ? -70.122 -33.755 -22.043 1.00 143.05 ? 74 GLN A CA 1 ATOM 351 C C . GLN A 1 47 ? -69.085 -33.527 -23.122 1.00 144.29 ? 74 GLN A C 1 ATOM 352 O O . GLN A 1 47 ? -67.987 -34.082 -23.069 1.00 147.11 ? 74 GLN A O 1 ATOM 353 C CB . GLN A 1 47 ? -70.851 -35.087 -22.255 1.00 136.32 ? 74 GLN A CB 1 ATOM 354 C CG . GLN A 1 47 ? -71.456 -35.654 -20.981 1.00 123.39 ? 74 GLN A CG 1 ATOM 355 C CD . GLN A 1 47 ? -72.261 -36.914 -21.223 1.00 110.87 ? 74 GLN A CD 1 ATOM 356 O OE1 . GLN A 1 47 ? -72.239 -37.844 -20.416 1.00 98.97 ? 74 GLN A OE1 1 ATOM 357 N NE2 . GLN A 1 47 ? -72.983 -36.949 -22.337 1.00 117.54 ? 74 GLN A NE2 1 ATOM 358 N N . ARG A 1 48 ? -69.437 -32.703 -24.098 1.00 139.20 ? 75 ARG A N 1 ATOM 359 C CA . ARG A 1 48 ? -68.536 -32.407 -25.188 1.00 133.27 ? 75 ARG A CA 1 ATOM 360 C C . ARG A 1 48 ? -67.686 -31.194 -24.782 1.00 136.66 ? 75 ARG A C 1 ATOM 361 O O . ARG A 1 48 ? -66.683 -30.876 -25.421 1.00 135.75 ? 75 ARG A O 1 ATOM 362 C CB . ARG A 1 48 ? -69.383 -32.063 -26.413 1.00 122.96 ? 75 ARG A CB 1 ATOM 363 C CG . ARG A 1 48 ? -70.166 -33.227 -26.991 1.00 124.35 ? 75 ARG A CG 1 ATOM 364 C CD . ARG A 1 48 ? -70.932 -32.797 -28.228 1.00 138.84 ? 75 ARG A CD 1 ATOM 365 N NE . ARG A 1 48 ? -70.219 -31.771 -28.979 1.00 145.90 ? 75 ARG A NE 1 ATOM 366 C CZ . ARG A 1 48 ? -70.804 -30.806 -29.678 1.00 145.77 ? 75 ARG A CZ 1 ATOM 367 N NH1 . ARG A 1 48 ? -72.127 -30.710 -29.732 1.00 144.65 ? 75 ARG A NH1 1 ATOM 368 N NH2 . ARG A 1 48 ? -70.055 -29.927 -30.313 1.00 138.97 ? 75 ARG A NH2 1 ATOM 369 N N . PHE A 1 49 ? -68.125 -30.520 -23.720 1.00 137.74 ? 76 PHE A N 1 ATOM 370 C CA . PHE A 1 49 ? -67.441 -29.377 -23.097 1.00 132.89 ? 76 PHE A CA 1 ATOM 371 C C . PHE A 1 49 ? -66.668 -29.747 -21.805 1.00 128.30 ? 76 PHE A C 1 ATOM 372 O O . PHE A 1 49 ? -67.301 -30.137 -20.827 1.00 137.09 ? 76 PHE A O 1 ATOM 373 C CB . PHE A 1 49 ? -68.459 -28.268 -22.809 1.00 138.60 ? 76 PHE A CB 1 ATOM 374 C CG . PHE A 1 49 ? -68.983 -27.580 -24.052 1.00 143.78 ? 76 PHE A CG 1 ATOM 375 C CD1 . PHE A 1 49 ? -69.585 -28.312 -25.067 1.00 144.72 ? 76 PHE A CD1 1 ATOM 376 C CD2 . PHE A 1 49 ? -68.880 -26.207 -24.203 1.00 143.84 ? 76 PHE A CD2 1 ATOM 377 C CE1 . PHE A 1 49 ? -70.068 -27.694 -26.207 1.00 140.10 ? 76 PHE A CE1 1 ATOM 378 C CE2 . PHE A 1 49 ? -69.364 -25.581 -25.343 1.00 142.17 ? 76 PHE A CE2 1 ATOM 379 C CZ . PHE A 1 49 ? -69.957 -26.327 -26.346 1.00 136.68 ? 76 PHE A CZ 1 ATOM 380 N N . GLU A 1 50 ? -65.343 -29.631 -21.745 1.00 120.88 ? 77 GLU A N 1 ATOM 381 C CA . GLU A 1 50 ? -64.680 -29.931 -20.462 1.00 117.41 ? 77 GLU A CA 1 ATOM 382 C C . GLU A 1 50 ? -63.943 -28.729 -19.846 1.00 123.86 ? 77 GLU A C 1 ATOM 383 O O . GLU A 1 50 ? -63.167 -28.058 -20.522 1.00 124.38 ? 77 GLU A O 1 ATOM 384 C CB . GLU A 1 50 ? -63.704 -31.102 -20.615 1.00 113.88 ? 77 GLU A CB 1 ATOM 385 C CG . GLU A 1 50 ? -62.899 -31.371 -19.345 1.00 118.45 ? 77 GLU A CG 1 ATOM 386 C CD . GLU A 1 50 ? -62.318 -32.773 -19.281 1.00 120.31 ? 77 GLU A CD 1 ATOM 387 O OE1 . GLU A 1 50 ? -62.970 -33.716 -19.777 1.00 137.07 ? 77 GLU A OE1 1 ATOM 388 O OE2 . GLU A 1 50 ? -61.212 -32.933 -18.722 1.00 107.47 ? 77 GLU A OE2 1 ATOM 389 N N . VAL A 1 51 ? -64.183 -28.483 -18.555 1.00 131.87 ? 78 VAL A N 1 ATOM 390 C CA . VAL A 1 51 ? -63.513 -27.413 -17.801 1.00 130.84 ? 78 VAL A CA 1 ATOM 391 C C . VAL A 1 51 ? -62.339 -27.860 -16.908 1.00 128.59 ? 78 VAL A C 1 ATOM 392 O O . VAL A 1 51 ? -62.521 -28.647 -15.976 1.00 131.07 ? 78 VAL A O 1 ATOM 393 C CB . VAL A 1 51 ? -64.535 -26.668 -16.904 1.00 137.60 ? 78 VAL A CB 1 ATOM 394 C CG1 . VAL A 1 51 ? -63.830 -25.700 -15.964 1.00 132.97 ? 78 VAL A CG1 1 ATOM 395 C CG2 . VAL A 1 51 ? -65.566 -25.942 -17.757 1.00 144.85 ? 78 VAL A CG2 1 ATOM 396 N N . ILE A 1 52 ? -61.141 -27.359 -17.209 1.00 125.50 ? 79 ILE A N 1 ATOM 397 C CA . ILE A 1 52 ? -59.919 -27.730 -16.486 1.00 127.53 ? 79 ILE A CA 1 ATOM 398 C C . ILE A 1 52 ? -59.341 -26.574 -15.653 1.00 131.36 ? 79 ILE A C 1 ATOM 399 O O . ILE A 1 52 ? -59.216 -25.458 -16.147 1.00 135.24 ? 79 ILE A O 1 ATOM 400 C CB . ILE A 1 52 ? -58.821 -28.237 -17.454 1.00 127.83 ? 79 ILE A CB 1 ATOM 401 C CG1 . ILE A 1 52 ? -59.383 -29.291 -18.411 1.00 134.58 ? 79 ILE A CG1 1 ATOM 402 C CG2 . ILE A 1 52 ? -57.647 -28.820 -16.678 1.00 126.28 ? 79 ILE A CG2 1 ATOM 403 C CD1 . ILE A 1 52 ? -59.787 -28.752 -19.773 1.00 133.33 ? 79 ILE A CD1 1 ATOM 404 N N . GLU A 1 53 ? -58.979 -26.847 -14.401 1.00 129.55 ? 80 GLU A N 1 ATOM 405 C CA . GLU A 1 53 ? -58.494 -25.810 -13.483 1.00 125.01 ? 80 GLU A CA 1 ATOM 406 C C . GLU A 1 53 ? -56.969 -25.806 -13.348 1.00 124.36 ? 80 GLU A C 1 ATOM 407 O O . GLU A 1 53 ? -56.325 -26.854 -13.373 1.00 132.55 ? 80 GLU A O 1 ATOM 408 C CB . GLU A 1 53 ? -59.145 -25.932 -12.100 1.00 133.38 ? 80 GLU A CB 1 ATOM 409 C CG . GLU A 1 53 ? -60.652 -26.130 -12.131 1.00 148.92 ? 80 GLU A CG 1 ATOM 410 C CD . GLU A 1 53 ? -61.386 -25.102 -11.279 1.00 148.61 ? 80 GLU A CD 1 ATOM 411 O OE1 . GLU A 1 53 ? -60.767 -24.553 -10.343 1.00 153.52 ? 80 GLU A OE1 1 ATOM 412 O OE2 . GLU A 1 53 ? -62.574 -24.822 -11.555 1.00 141.20 ? 80 GLU A OE2 1 ATOM 413 N N . PHE A 1 54 ? -56.413 -24.604 -13.215 1.00 121.15 ? 81 PHE A N 1 ATOM 414 C CA . PHE A 1 54 ? -55.005 -24.383 -12.890 1.00 128.38 ? 81 PHE A CA 1 ATOM 415 C C . PHE A 1 54 ? -54.718 -24.824 -11.457 1.00 132.34 ? 81 PHE A C 1 ATOM 416 O O . PHE A 1 54 ? -55.575 -24.685 -10.583 1.00 133.13 ? 81 PHE A O 1 ATOM 417 C CB . PHE A 1 54 ? -54.625 -22.908 -13.061 1.00 129.02 ? 81 PHE A CB 1 ATOM 418 C CG . PHE A 1 54 ? -54.602 -22.438 -14.490 1.00 127.92 ? 81 PHE A CG 1 ATOM 419 C CD1 . PHE A 1 54 ? -55.704 -21.811 -15.045 1.00 129.29 ? 81 PHE A CD1 1 ATOM 420 C CD2 . PHE A 1 54 ? -53.474 -22.607 -15.272 1.00 126.61 ? 81 PHE A CD2 1 ATOM 421 C CE1 . PHE A 1 54 ? -55.689 -21.370 -16.356 1.00 128.73 ? 81 PHE A CE1 1 ATOM 422 C CE2 . PHE A 1 54 ? -53.450 -22.167 -16.586 1.00 128.90 ? 81 PHE A CE2 1 ATOM 423 C CZ . PHE A 1 54 ? -54.560 -21.548 -17.128 1.00 131.67 ? 81 PHE A CZ 1 ATOM 424 N N . ASP A 1 55 ? -53.528 -25.380 -11.221 1.00 136.11 ? 82 ASP A N 1 ATOM 425 C CA . ASP A 1 55 ? -53.179 -25.904 -9.897 1.00 141.66 ? 82 ASP A CA 1 ATOM 426 C C . ASP A 1 55 ? -53.274 -24.806 -8.856 1.00 140.89 ? 82 ASP A C 1 ATOM 427 O O . ASP A 1 55 ? -53.574 -25.066 -7.691 1.00 145.07 ? 82 ASP A O 1 ATOM 428 C CB . ASP A 1 55 ? -51.763 -26.489 -9.915 1.00 147.85 ? 82 ASP A CB 1 ATOM 429 C CG . ASP A 1 55 ? -51.440 -27.298 -8.669 1.00 154.83 ? 82 ASP A CG 1 ATOM 430 O OD1 . ASP A 1 55 ? -52.338 -27.492 -7.821 1.00 160.14 ? 82 ASP A OD1 1 ATOM 431 O OD2 . ASP A 1 55 ? -50.306 -27.816 -8.577 1.00 154.54 ? 82 ASP A OD2 1 ATOM 432 N N . ASP A 1 56 ? -53.047 -23.573 -9.286 1.00 141.24 ? 83 ASP A N 1 ATOM 433 C CA . ASP A 1 56 ? -53.117 -22.451 -8.375 1.00 141.64 ? 83 ASP A CA 1 ATOM 434 C C . ASP A 1 56 ? -54.562 -21.960 -8.465 1.00 139.77 ? 83 ASP A C 1 ATOM 435 O O . ASP A 1 56 ? -55.176 -22.019 -9.531 1.00 135.93 ? 83 ASP A O 1 ATOM 436 C CB . ASP A 1 56 ? -52.059 -21.374 -8.689 1.00 134.86 ? 83 ASP A CB 1 ATOM 437 C CG . ASP A 1 56 ? -52.151 -20.815 -10.103 1.00 132.85 ? 83 ASP A CG 1 ATOM 438 O OD1 . ASP A 1 56 ? -53.045 -21.209 -10.879 1.00 136.44 ? 83 ASP A OD1 1 ATOM 439 O OD2 . ASP A 1 56 ? -51.300 -19.963 -10.440 1.00 127.83 ? 83 ASP A OD2 1 ATOM 440 N N . GLY A 1 57 ? -55.123 -21.522 -7.344 1.00 142.28 ? 84 GLY A N 1 ATOM 441 C CA . GLY A 1 57 ? -56.490 -21.021 -7.291 1.00 142.33 ? 84 GLY A CA 1 ATOM 442 C C . GLY A 1 57 ? -56.891 -19.925 -8.270 1.00 144.30 ? 84 GLY A C 1 ATOM 443 O O . GLY A 1 57 ? -57.890 -19.240 -8.051 1.00 152.64 ? 84 GLY A O 1 ATOM 444 N N . SER A 1 58 ? -56.116 -19.759 -9.338 1.00 132.73 ? 85 SER A N 1 ATOM 445 C CA . SER A 1 58 ? -56.394 -18.781 -10.390 1.00 126.77 ? 85 SER A CA 1 ATOM 446 C C . SER A 1 58 ? -57.653 -19.071 -11.212 1.00 125.52 ? 85 SER A C 1 ATOM 447 O O . SER A 1 58 ? -58.762 -19.093 -10.683 1.00 124.21 ? 85 SER A O 1 ATOM 448 C CB . SER A 1 58 ? -55.190 -18.685 -11.332 1.00 127.98 ? 85 SER A CB 1 ATOM 449 O OG . SER A 1 58 ? -53.985 -18.496 -10.612 1.00 123.35 ? 85 SER A OG 1 ATOM 450 N N . GLY A 1 59 ? -57.473 -19.284 -12.512 1.00 130.69 ? 86 GLY A N 1 ATOM 451 C CA . GLY A 1 59 ? -58.586 -19.528 -13.416 1.00 129.51 ? 86 GLY A CA 1 ATOM 452 C C . GLY A 1 59 ? -58.676 -20.933 -13.982 1.00 128.72 ? 86 GLY A C 1 ATOM 453 O O . GLY A 1 59 ? -58.210 -21.894 -13.369 1.00 128.18 ? 86 GLY A O 1 ATOM 454 N N . SER A 1 60 ? -59.308 -21.054 -15.149 1.00 126.07 ? 87 SER A N 1 ATOM 455 C CA . SER A 1 60 ? -59.619 -22.358 -15.731 1.00 125.01 ? 87 SER A CA 1 ATOM 456 C C . SER A 1 60 ? -59.617 -22.306 -17.267 1.00 129.59 ? 87 SER A C 1 ATOM 457 O O . SER A 1 60 ? -59.642 -21.228 -17.860 1.00 128.84 ? 87 SER A O 1 ATOM 458 C CB . SER A 1 60 ? -60.971 -22.856 -15.212 1.00 125.97 ? 87 SER A CB 1 ATOM 459 O OG . SER A 1 60 ? -62.047 -22.158 -15.814 1.00 124.75 ? 87 SER A OG 1 ATOM 460 N N . VAL A 1 61 ? -59.588 -23.480 -17.899 1.00 134.09 ? 88 VAL A N 1 ATOM 461 C CA . VAL A 1 61 ? -59.667 -23.611 -19.358 1.00 129.51 ? 88 VAL A CA 1 ATOM 462 C C . VAL A 1 61 ? -60.931 -24.352 -19.814 1.00 130.04 ? 88 VAL A C 1 ATOM 463 O O . VAL A 1 61 ? -61.266 -25.401 -19.265 1.00 129.48 ? 88 VAL A O 1 ATOM 464 C CB . VAL A 1 61 ? -58.414 -24.336 -19.915 1.00 129.01 ? 88 VAL A CB 1 ATOM 465 C CG1 . VAL A 1 61 ? -58.525 -24.554 -21.419 1.00 127.78 ? 88 VAL A CG1 1 ATOM 466 C CG2 . VAL A 1 61 ? -57.153 -23.548 -19.579 1.00 132.23 ? 88 VAL A CG2 1 ATOM 467 N N . LEU A 1 62 ? -61.637 -23.802 -20.802 1.00 132.68 ? 89 LEU A N 1 ATOM 468 C CA . LEU A 1 62 ? -62.721 -24.530 -21.470 1.00 132.74 ? 89 LEU A CA 1 ATOM 469 C C . LEU A 1 62 ? -62.318 -25.205 -22.787 1.00 131.72 ? 89 LEU A C 1 ATOM 470 O O . LEU A 1 62 ? -61.990 -24.537 -23.769 1.00 131.20 ? 89 LEU A O 1 ATOM 471 C CB . LEU A 1 62 ? -63.896 -23.590 -21.738 1.00 128.66 ? 89 LEU A CB 1 ATOM 472 C CG . LEU A 1 62 ? -65.089 -24.259 -22.426 1.00 120.92 ? 89 LEU A CG 1 ATOM 473 C CD1 . LEU A 1 62 ? -65.681 -25.350 -21.548 1.00 120.39 ? 89 LEU A CD1 1 ATOM 474 C CD2 . LEU A 1 62 ? -66.146 -23.234 -22.804 1.00 118.39 ? 89 LEU A CD2 1 ATOM 475 N N . ARG A 1 63 ? -62.347 -26.536 -22.792 1.00 129.96 ? 90 ARG A N 1 ATOM 476 C CA . ARG A 1 63 ? -61.948 -27.333 -23.952 1.00 122.58 ? 90 ARG A CA 1 ATOM 477 C C . ARG A 1 63 ? -63.126 -28.064 -24.620 1.00 124.36 ? 90 ARG A C 1 ATOM 478 O O . ARG A 1 63 ? -63.854 -28.801 -23.958 1.00 132.68 ? 90 ARG A O 1 ATOM 479 C CB . ARG A 1 63 ? -60.883 -28.337 -23.512 1.00 121.45 ? 90 ARG A CB 1 ATOM 480 C CG . ARG A 1 63 ? -60.418 -29.325 -24.558 1.00 115.00 ? 90 ARG A CG 1 ATOM 481 C CD . ARG A 1 63 ? -59.456 -30.313 -23.914 1.00 106.67 ? 90 ARG A CD 1 ATOM 482 N NE . ARG A 1 63 ? -58.933 -31.293 -24.861 1.00 109.05 ? 90 ARG A NE 1 ATOM 483 C CZ . ARG A 1 63 ? -57.750 -31.185 -25.450 1.00 116.25 ? 90 ARG A CZ 1 ATOM 484 N NH1 . ARG A 1 63 ? -56.987 -30.134 -25.190 1.00 114.49 ? 90 ARG A NH1 1 ATOM 485 N NH2 . ARG A 1 63 ? -57.339 -32.111 -26.306 1.00 123.35 ? 90 ARG A NH2 1 ATOM 486 N N . ILE A 1 64 ? -63.311 -27.860 -25.924 1.00 115.78 ? 91 ILE A N 1 ATOM 487 C CA . ILE A 1 64 ? -64.394 -28.509 -26.676 1.00 116.25 ? 91 ILE A CA 1 ATOM 488 C C . ILE A 1 64 ? -63.865 -29.501 -27.720 1.00 124.49 ? 91 ILE A C 1 ATOM 489 O O . ILE A 1 64 ? -63.358 -29.088 -28.762 1.00 130.78 ? 91 ILE A O 1 ATOM 490 C CB . ILE A 1 64 ? -65.317 -27.491 -27.376 1.00 119.75 ? 91 ILE A CB 1 ATOM 491 C CG1 . ILE A 1 64 ? -65.565 -26.279 -26.476 1.00 131.43 ? 91 ILE A CG1 1 ATOM 492 C CG2 . ILE A 1 64 ? -66.652 -28.142 -27.720 1.00 123.41 ? 91 ILE A CG2 1 ATOM 493 C CD1 . ILE A 1 64 ? -66.377 -25.179 -27.139 1.00 138.12 ? 91 ILE A CD1 1 ATOM 494 N N . GLN A 1 65 ? -63.978 -30.798 -27.449 1.00 128.36 ? 92 GLN A N 1 ATOM 495 C CA . GLN A 1 65 ? -63.443 -31.812 -28.358 1.00 129.35 ? 92 GLN A CA 1 ATOM 496 C C . GLN A 1 65 ? -64.276 -33.094 -28.352 1.00 130.02 ? 92 GLN A C 1 ATOM 497 O O . GLN A 1 65 ? -64.587 -33.628 -27.288 1.00 128.17 ? 92 GLN A O 1 ATOM 498 C CB . GLN A 1 65 ? -61.992 -32.133 -27.999 1.00 123.72 ? 92 GLN A CB 1 ATOM 499 C CG . GLN A 1 65 ? -61.351 -33.170 -28.897 1.00 125.04 ? 92 GLN A CG 1 ATOM 500 C CD . GLN A 1 65 ? -60.127 -33.808 -28.276 1.00 130.61 ? 92 GLN A CD 1 ATOM 501 O OE1 . GLN A 1 65 ? -59.846 -33.621 -27.093 1.00 125.42 ? 92 GLN A OE1 1 ATOM 502 N NE2 . GLN A 1 65 ? -59.389 -34.566 -29.077 1.00 151.83 ? 92 GLN A NE2 1 ATOM 503 N N . PRO A 1 66 ? -64.646 -33.593 -29.547 1.00 132.86 ? 93 PRO A N 1 ATOM 504 C CA . PRO A 1 66 ? -64.374 -33.025 -30.874 1.00 129.90 ? 93 PRO A CA 1 ATOM 505 C C . PRO A 1 66 ? -65.367 -31.945 -31.272 1.00 126.48 ? 93 PRO A C 1 ATOM 506 O O . PRO A 1 66 ? -66.551 -32.016 -30.899 1.00 126.65 ? 93 PRO A O 1 ATOM 507 C CB . PRO A 1 66 ? -64.487 -34.240 -31.799 1.00 130.52 ? 93 PRO A CB 1 ATOM 508 C CG . PRO A 1 66 ? -65.470 -35.117 -31.129 1.00 135.00 ? 93 PRO A CG 1 ATOM 509 C CD . PRO A 1 66 ? -65.308 -34.908 -29.642 1.00 139.44 ? 93 PRO A CD 1 ATOM 510 N N . LEU A 1 67 ? -64.880 -30.945 -32.001 1.00 125.76 ? 94 LEU A N 1 ATOM 511 C CA . LEU A 1 67 ? -65.728 -29.871 -32.485 1.00 126.08 ? 94 LEU A CA 1 ATOM 512 C C . LEU A 1 67 ? -66.804 -30.390 -33.417 1.00 129.01 ? 94 LEU A C 1 ATOM 513 O O . LEU A 1 67 ? -66.569 -31.262 -34.262 1.00 132.80 ? 94 LEU A O 1 ATOM 514 C CB . LEU A 1 67 ? -64.885 -28.798 -33.210 1.00 126.44 ? 94 LEU A CB 1 ATOM 515 C CG . LEU A 1 67 ? -63.963 -27.910 -32.356 1.00 123.58 ? 94 LEU A CG 1 ATOM 516 C CD1 . LEU A 1 67 ? -62.958 -27.169 -33.218 1.00 120.09 ? 94 LEU A CD1 1 ATOM 517 C CD2 . LEU A 1 67 ? -64.754 -26.902 -31.529 1.00 124.43 ? 94 LEU A CD2 1 ATOM 518 N N . ARG A 1 68 ? -67.991 -29.825 -33.247 1.00 129.58 ? 95 ARG A N 1 ATOM 519 C CA . ARG A 1 68 ? -69.124 -30.141 -34.093 1.00 132.23 ? 95 ARG A CA 1 ATOM 520 C C . ARG A 1 68 ? -69.597 -28.808 -34.688 1.00 135.02 ? 95 ARG A C 1 ATOM 521 O O . ARG A 1 68 ? -69.811 -27.826 -33.966 1.00 133.72 ? 95 ARG A O 1 ATOM 522 C CB . ARG A 1 68 ? -70.233 -30.846 -33.286 1.00 134.22 ? 95 ARG A CB 1 ATOM 523 C CG . ARG A 1 68 ? -70.475 -32.318 -33.695 1.00 144.25 ? 95 ARG A CG 1 ATOM 524 C CD . ARG A 1 68 ? -70.996 -33.136 -32.529 1.00 153.27 ? 95 ARG A CD 1 ATOM 525 N NE . ARG A 1 68 ? -70.106 -34.217 -32.128 1.00 151.43 ? 95 ARG A NE 1 ATOM 526 C CZ . ARG A 1 68 ? -70.561 -35.394 -31.699 1.00 140.87 ? 95 ARG A CZ 1 ATOM 527 N NH1 . ARG A 1 68 ? -71.859 -35.580 -31.620 1.00 141.36 ? 95 ARG A NH1 1 ATOM 528 N NH2 . ARG A 1 68 ? -69.721 -36.358 -31.343 1.00 124.56 ? 95 ARG A NH2 1 ATOM 529 N N . THR A 1 69 ? -69.780 -28.796 -36.002 1.00 134.14 ? 96 THR A N 1 ATOM 530 C CA . THR A 1 69 ? -70.316 -27.648 -36.740 1.00 133.23 ? 96 THR A CA 1 ATOM 531 C C . THR A 1 69 ? -71.699 -27.911 -37.364 1.00 127.69 ? 96 THR A C 1 ATOM 532 O O . THR A 1 69 ? -71.961 -29.012 -37.836 1.00 118.62 ? 96 THR A O 1 ATOM 533 C CB . THR A 1 69 ? -69.321 -27.215 -37.846 1.00 133.69 ? 96 THR A CB 1 ATOM 534 O OG1 . THR A 1 69 ? -69.908 -26.209 -38.673 1.00 137.91 ? 96 THR A OG1 1 ATOM 535 C CG2 . THR A 1 69 ? -68.929 -28.411 -38.689 1.00 133.60 ? 96 THR A CG2 1 ATOM 536 N N . PRO A 1 70 ? -72.581 -26.892 -37.358 1.00 129.08 ? 97 PRO A N 1 ATOM 537 C CA . PRO A 1 70 ? -72.471 -25.538 -36.798 1.00 130.37 ? 97 PRO A CA 1 ATOM 538 C C . PRO A 1 70 ? -73.126 -25.341 -35.432 1.00 129.07 ? 97 PRO A C 1 ATOM 539 O O . PRO A 1 70 ? -73.418 -24.204 -35.066 1.00 130.79 ? 97 PRO A O 1 ATOM 540 C CB . PRO A 1 70 ? -73.159 -24.681 -37.867 1.00 127.11 ? 97 PRO A CB 1 ATOM 541 C CG . PRO A 1 70 ? -74.045 -25.639 -38.657 1.00 122.71 ? 97 PRO A CG 1 ATOM 542 C CD . PRO A 1 70 ? -73.828 -27.032 -38.119 1.00 128.61 ? 97 PRO A CD 1 ATOM 543 N N . ARG A 1 71 ? -73.372 -26.424 -34.705 1.00 127.29 ? 98 ARG A N 1 ATOM 544 C CA . ARG A 1 71 ? -73.943 -26.356 -33.359 1.00 130.72 ? 98 ARG A CA 1 ATOM 545 C C . ARG A 1 71 ? -73.136 -25.453 -32.426 1.00 132.82 ? 98 ARG A C 1 ATOM 546 O O . ARG A 1 71 ? -73.693 -24.575 -31.762 1.00 134.86 ? 98 ARG A O 1 ATOM 547 C CB . ARG A 1 71 ? -74.057 -27.768 -32.806 1.00 126.00 ? 98 ARG A CB 1 ATOM 548 C CG . ARG A 1 71 ? -75.091 -28.549 -33.581 1.00 120.68 ? 98 ARG A CG 1 ATOM 549 C CD . ARG A 1 71 ? -74.513 -29.842 -34.088 1.00 132.11 ? 98 ARG A CD 1 ATOM 550 N NE . ARG A 1 71 ? -74.433 -30.852 -33.046 1.00 140.93 ? 98 ARG A NE 1 ATOM 551 C CZ . ARG A 1 71 ? -74.160 -32.129 -33.277 1.00 148.52 ? 98 ARG A CZ 1 ATOM 552 N NH1 . ARG A 1 71 ? -73.920 -32.547 -34.512 1.00 152.06 ? 98 ARG A NH1 1 ATOM 553 N NH2 . ARG A 1 71 ? -74.102 -32.978 -32.267 1.00 147.20 ? 98 ARG A NH2 1 ATOM 554 N N . ASP A 1 72 ? -71.828 -25.687 -32.364 1.00 128.52 ? 99 ASP A N 1 ATOM 555 C CA . ASP A 1 72 ? -70.982 -25.088 -31.337 1.00 129.67 ? 99 ASP A CA 1 ATOM 556 C C . ASP A 1 72 ? -70.840 -23.617 -31.654 1.00 124.56 ? 99 ASP A C 1 ATOM 557 O O . ASP A 1 72 ? -70.609 -22.785 -30.775 1.00 124.45 ? 99 ASP A O 1 ATOM 558 C CB . ASP A 1 72 ? -69.607 -25.745 -31.288 1.00 132.23 ? 99 ASP A CB 1 ATOM 559 C CG . ASP A 1 72 ? -69.665 -27.166 -30.805 1.00 135.81 ? 99 ASP A CG 1 ATOM 560 O OD1 . ASP A 1 72 ? -70.669 -27.536 -30.161 1.00 140.18 ? 99 ASP A OD1 1 ATOM 561 O OD2 . ASP A 1 72 ? -68.713 -27.927 -31.072 1.00 135.64 ? 99 ASP A OD2 1 ATOM 562 N N . GLU A 1 73 ? -70.968 -23.325 -32.942 1.00 122.83 ? 100 GLU A N 1 ATOM 563 C CA . GLU A 1 73 ? -70.888 -21.976 -33.466 1.00 127.92 ? 100 GLU A CA 1 ATOM 564 C C . GLU A 1 73 ? -71.879 -21.075 -32.747 1.00 136.50 ? 100 GLU A C 1 ATOM 565 O O . GLU A 1 73 ? -73.066 -21.049 -33.067 1.00 145.78 ? 100 GLU A O 1 ATOM 566 C CB . GLU A 1 73 ? -71.168 -21.984 -34.967 1.00 128.23 ? 100 GLU A CB 1 ATOM 567 C CG . GLU A 1 73 ? -70.273 -21.088 -35.790 1.00 125.16 ? 100 GLU A CG 1 ATOM 568 C CD . GLU A 1 73 ? -69.937 -21.714 -37.128 1.00 124.35 ? 100 GLU A CD 1 ATOM 569 O OE1 . GLU A 1 73 ? -70.864 -22.212 -37.801 1.00 120.77 ? 100 GLU A OE1 1 ATOM 570 O OE2 . GLU A 1 73 ? -68.748 -21.726 -37.503 1.00 130.05 ? 100 GLU A OE2 1 ATOM 571 N N . ALA A 1 74 ? -71.369 -20.330 -31.774 1.00 136.60 ? 101 ALA A N 1 ATOM 572 C CA . ALA A 1 74 ? -72.200 -19.544 -30.878 1.00 141.19 ? 101 ALA A CA 1 ATOM 573 C C . ALA A 1 74 ? -71.339 -18.504 -30.180 1.00 139.80 ? 101 ALA A C 1 ATOM 574 O O . ALA A 1 74 ? -70.110 -18.554 -30.249 1.00 136.14 ? 101 ALA A O 1 ATOM 575 C CB . ALA A 1 74 ? -72.897 -20.441 -29.863 1.00 137.72 ? 101 ALA A CB 1 ATOM 576 N N . ILE A 1 75 ? -71.988 -17.561 -29.508 1.00 139.64 ? 102 ILE A N 1 ATOM 577 C CA . ILE A 1 75 ? -71.286 -16.581 -28.694 1.00 138.18 ? 102 ILE A CA 1 ATOM 578 C C . ILE A 1 75 ? -71.174 -17.042 -27.240 1.00 142.71 ? 102 ILE A C 1 ATOM 579 O O . ILE A 1 75 ? -72.188 -17.222 -26.566 1.00 154.39 ? 102 ILE A O 1 ATOM 580 C CB . ILE A 1 75 ? -72.014 -15.213 -28.742 1.00 139.69 ? 102 ILE A CB 1 ATOM 581 C CG1 . ILE A 1 75 ? -72.305 -14.792 -30.193 1.00 143.82 ? 102 ILE A CG1 1 ATOM 582 C CG2 . ILE A 1 75 ? -71.299 -14.163 -27.880 1.00 143.99 ? 102 ILE A CG2 1 ATOM 583 C CD1 . ILE A 1 75 ? -71.116 -14.309 -30.970 1.00 145.85 ? 102 ILE A CD1 1 ATOM 584 N N . TYR A 1 76 ? -69.949 -17.249 -26.764 1.00 139.37 ? 103 TYR A N 1 ATOM 585 C CA . TYR A 1 76 ? -69.730 -17.680 -25.382 1.00 141.97 ? 103 TYR A CA 1 ATOM 586 C C . TYR A 1 76 ? -69.183 -16.543 -24.515 1.00 143.29 ? 103 TYR A C 1 ATOM 587 O O . TYR A 1 76 ? -68.818 -15.486 -25.030 1.00 147.10 ? 103 TYR A O 1 ATOM 588 C CB . TYR A 1 76 ? -68.798 -18.896 -25.340 1.00 137.65 ? 103 TYR A CB 1 ATOM 589 C CG . TYR A 1 76 ? -69.394 -20.137 -25.973 1.00 137.36 ? 103 TYR A CG 1 ATOM 590 C CD1 . TYR A 1 76 ? -69.408 -20.309 -27.353 1.00 138.10 ? 103 TYR A CD1 1 ATOM 591 C CD2 . TYR A 1 76 ? -69.950 -21.138 -25.185 1.00 138.44 ? 103 TYR A CD2 1 ATOM 592 C CE1 . TYR A 1 76 ? -69.962 -21.443 -27.929 1.00 143.08 ? 103 TYR A CE1 1 ATOM 593 C CE2 . TYR A 1 76 ? -70.499 -22.276 -25.748 1.00 140.65 ? 103 TYR A CE2 1 ATOM 594 C CZ . TYR A 1 76 ? -70.505 -22.424 -27.121 1.00 139.96 ? 103 TYR A CZ 1 ATOM 595 O OH . TYR A 1 76 ? -71.051 -23.556 -27.686 1.00 128.45 ? 103 TYR A OH 1 ATOM 596 N N . GLU A 1 77 ? -69.116 -16.769 -23.204 1.00 141.02 ? 104 GLU A N 1 ATOM 597 C CA . GLU A 1 77 ? -68.527 -15.796 -22.284 1.00 145.40 ? 104 GLU A CA 1 ATOM 598 C C . GLU A 1 77 ? -67.888 -16.400 -21.041 1.00 147.83 ? 104 GLU A C 1 ATOM 599 O O . GLU A 1 77 ? -68.312 -17.445 -20.552 1.00 147.73 ? 104 GLU A O 1 ATOM 600 C CB . GLU A 1 77 ? -69.586 -14.795 -21.815 1.00 154.50 ? 104 GLU A CB 1 ATOM 601 C CG . GLU A 1 77 ? -69.715 -13.550 -22.653 1.00 160.63 ? 104 GLU A CG 1 ATOM 602 C CD . GLU A 1 77 ? -70.740 -12.586 -22.095 1.00 179.13 ? 104 GLU A CD 1 ATOM 603 O OE1 . GLU A 1 77 ? -71.935 -12.731 -22.423 1.00 188.41 ? 104 GLU A OE1 1 ATOM 604 O OE2 . GLU A 1 77 ? -70.349 -11.688 -21.319 1.00 176.93 ? 104 GLU A OE2 1 ATOM 605 N N . CYS A 1 78 ? -66.860 -15.724 -20.536 1.00 150.33 ? 105 CYS A N 1 ATOM 606 C CA . CYS A 1 78 ? -66.204 -16.108 -19.293 1.00 155.68 ? 105 CYS A CA 1 ATOM 607 C C . CYS A 1 78 ? -66.679 -15.163 -18.179 1.00 160.15 ? 105 CYS A C 1 ATOM 608 O O . CYS A 1 78 ? -66.645 -13.947 -18.358 1.00 161.15 ? 105 CYS A O 1 ATOM 609 C CB . CYS A 1 78 ? -64.686 -16.047 -19.476 1.00 150.86 ? 105 CYS A CB 1 ATOM 610 S SG . CYS A 1 78 ? -63.691 -16.619 -18.100 1.00 153.57 ? 105 CYS A SG 1 ATOM 611 N N . VAL A 1 79 ? -67.117 -15.702 -17.040 1.00 158.08 ? 106 VAL A N 1 ATOM 612 C CA . VAL A 1 79 ? -67.456 -14.868 -15.878 1.00 152.41 ? 106 VAL A CA 1 ATOM 613 C C . VAL A 1 79 ? -66.722 -15.216 -14.571 1.00 149.06 ? 106 VAL A C 1 ATOM 614 O O . VAL A 1 79 ? -66.860 -16.325 -14.057 1.00 145.91 ? 106 VAL A O 1 ATOM 615 C CB . VAL A 1 79 ? -68.979 -14.924 -15.598 1.00 149.50 ? 106 VAL A CB 1 ATOM 616 C CG1 . VAL A 1 79 ? -69.324 -14.145 -14.336 1.00 153.85 ? 106 VAL A CG1 1 ATOM 617 C CG2 . VAL A 1 79 ? -69.764 -14.395 -16.794 1.00 149.56 ? 106 VAL A CG2 1 ATOM 618 N N . ALA A 1 80 ? -65.954 -14.268 -14.035 1.00 155.31 ? 107 ALA A N 1 ATOM 619 C CA . ALA A 1 80 ? -65.294 -14.444 -12.736 1.00 158.22 ? 107 ALA A CA 1 ATOM 620 C C . ALA A 1 80 ? -66.002 -13.622 -11.655 1.00 165.87 ? 107 ALA A C 1 ATOM 621 O O . ALA A 1 80 ? -66.278 -12.442 -11.862 1.00 172.63 ? 107 ALA A O 1 ATOM 622 C CB . ALA A 1 80 ? -63.826 -14.058 -12.822 1.00 165.05 ? 107 ALA A CB 1 ATOM 623 N N . SER A 1 81 ? -66.300 -14.232 -10.508 1.00 164.44 ? 108 SER A N 1 ATOM 624 C CA . SER A 1 81 ? -67.120 -13.559 -9.500 1.00 166.16 ? 108 SER A CA 1 ATOM 625 C C . SER A 1 81 ? -66.819 -13.954 -8.051 1.00 168.08 ? 108 SER A C 1 ATOM 626 O O . SER A 1 81 ? -66.697 -15.136 -7.734 1.00 167.30 ? 108 SER A O 1 ATOM 627 C CB . SER A 1 81 ? -68.604 -13.819 -9.780 1.00 164.95 ? 108 SER A CB 1 ATOM 628 O OG . SER A 1 81 ? -68.865 -15.203 -9.935 1.00 163.63 ? 108 SER A OG 1 ATOM 629 N N . ASN A 1 82 ? -66.708 -12.955 -7.177 1.00 174.15 ? 109 ASN A N 1 ATOM 630 C CA . ASN A 1 82 ? -66.698 -13.189 -5.735 1.00 174.46 ? 109 ASN A CA 1 ATOM 631 C C . ASN A 1 82 ? -67.619 -12.198 -5.021 1.00 175.35 ? 109 ASN A C 1 ATOM 632 O O . ASN A 1 82 ? -68.172 -11.299 -5.648 1.00 182.19 ? 109 ASN A O 1 ATOM 633 C CB . ASN A 1 82 ? -65.272 -13.098 -5.167 1.00 170.99 ? 109 ASN A CB 1 ATOM 634 C CG . ASN A 1 82 ? -64.611 -11.743 -5.414 1.00 172.65 ? 109 ASN A CG 1 ATOM 635 O OD1 . ASN A 1 82 ? -65.247 -10.791 -5.864 1.00 181.69 ? 109 ASN A OD1 1 ATOM 636 N ND2 . ASN A 1 82 ? -63.322 -11.655 -5.104 1.00 167.67 ? 109 ASN A ND2 1 ATOM 637 N N . ASN A 1 83 ? -67.822 -12.383 -3.720 1.00 165.89 ? 110 ASN A N 1 ATOM 638 C CA . ASN A 1 83 ? -68.749 -11.539 -2.964 1.00 167.52 ? 110 ASN A CA 1 ATOM 639 C C . ASN A 1 83 ? -68.217 -10.120 -2.722 1.00 171.95 ? 110 ASN A C 1 ATOM 640 O O . ASN A 1 83 ? -68.619 -9.455 -1.768 1.00 171.61 ? 110 ASN A O 1 ATOM 641 C CB . ASN A 1 83 ? -69.110 -12.199 -1.633 1.00 172.66 ? 110 ASN A CB 1 ATOM 642 C CG . ASN A 1 83 ? -70.355 -13.061 -1.734 1.00 175.22 ? 110 ASN A CG 1 ATOM 643 O OD1 . ASN A 1 83 ? -70.275 -14.263 -1.989 1.00 172.20 ? 110 ASN A OD1 1 ATOM 644 N ND2 . ASN A 1 83 ? -71.517 -12.445 -1.543 1.00 170.91 ? 110 ASN A ND2 1 ATOM 645 N N . VAL A 1 84 ? -67.315 -9.666 -3.589 1.00 178.55 ? 111 VAL A N 1 ATOM 646 C CA . VAL A 1 84 ? -66.735 -8.327 -3.514 1.00 179.93 ? 111 VAL A CA 1 ATOM 647 C C . VAL A 1 84 ? -66.902 -7.609 -4.855 1.00 175.73 ? 111 VAL A C 1 ATOM 648 O O . VAL A 1 84 ? -66.725 -6.393 -4.959 1.00 170.28 ? 111 VAL A O 1 ATOM 649 C CB . VAL A 1 84 ? -65.228 -8.397 -3.129 1.00 173.88 ? 111 VAL A CB 1 ATOM 650 C CG1 . VAL A 1 84 ? -64.635 -7.010 -2.913 1.00 172.79 ? 111 VAL A CG1 1 ATOM 651 C CG2 . VAL A 1 84 ? -65.039 -9.228 -1.877 1.00 168.73 ? 111 VAL A CG2 1 ATOM 652 N N . GLY A 1 85 ? -67.288 -8.366 -5.876 1.00 177.51 ? 112 GLY A N 1 ATOM 653 C CA . GLY A 1 85 ? -67.427 -7.819 -7.213 1.00 176.13 ? 112 GLY A CA 1 ATOM 654 C C . GLY A 1 85 ? -67.581 -8.908 -8.254 1.00 184.50 ? 112 GLY A C 1 ATOM 655 O O . GLY A 1 85 ? -67.548 -10.095 -7.939 1.00 187.14 ? 112 GLY A O 1 ATOM 656 N N . GLU A 1 86 ? -67.738 -8.510 -9.507 1.00 186.36 ? 113 GLU A N 1 ATOM 657 C CA . GLU A 1 86 ? -68.037 -9.462 -10.560 1.00 184.38 ? 113 GLU A CA 1 ATOM 658 C C . GLU A 1 86 ? -67.456 -8.935 -11.853 1.00 185.01 ? 113 GLU A C 1 ATOM 659 O O . GLU A 1 86 ? -67.549 -7.746 -12.159 1.00 185.33 ? 113 GLU A O 1 ATOM 660 C CB . GLU A 1 86 ? -69.551 -9.664 -10.691 1.00 181.82 ? 113 GLU A CB 1 ATOM 661 C CG . GLU A 1 86 ? -69.977 -10.967 -11.344 1.00 179.05 ? 113 GLU A CG 1 ATOM 662 C CD . GLU A 1 86 ? -71.485 -11.079 -11.479 1.00 181.76 ? 113 GLU A CD 1 ATOM 663 O OE1 . GLU A 1 86 ? -72.066 -12.023 -10.904 1.00 189.01 ? 113 GLU A OE1 1 ATOM 664 O OE2 . GLU A 1 86 ? -72.089 -10.221 -12.155 1.00 181.89 ? 113 GLU A OE2 1 ATOM 665 N N . ILE A 1 87 ? -66.860 -9.841 -12.616 1.00 184.51 ? 114 ILE A N 1 ATOM 666 C CA . ILE A 1 87 ? -66.354 -9.499 -13.927 1.00 178.95 ? 114 ILE A CA 1 ATOM 667 C C . ILE A 1 87 ? -66.722 -10.578 -14.939 1.00 174.65 ? 114 ILE A C 1 ATOM 668 O O . ILE A 1 87 ? -66.902 -11.746 -14.594 1.00 177.49 ? 114 ILE A O 1 ATOM 669 C CB . ILE A 1 87 ? -64.817 -9.296 -13.860 1.00 183.07 ? 114 ILE A CB 1 ATOM 670 C CG1 . ILE A 1 87 ? -64.283 -8.598 -15.107 1.00 181.53 ? 114 ILE A CG1 1 ATOM 671 C CG2 . ILE A 1 87 ? -64.103 -10.614 -13.621 1.00 185.22 ? 114 ILE A CG2 1 ATOM 672 C CD1 . ILE A 1 87 ? -62.887 -8.045 -14.939 1.00 175.80 ? 114 ILE A CD1 1 ATOM 673 N N . SER A 1 88 ? -66.864 -10.155 -16.187 1.00 173.31 ? 115 SER A N 1 ATOM 674 C CA . SER A 1 88 ? -67.165 -11.035 -17.305 1.00 174.06 ? 115 SER A CA 1 ATOM 675 C C . SER A 1 88 ? -66.426 -10.630 -18.582 1.00 177.36 ? 115 SER A C 1 ATOM 676 O O . SER A 1 88 ? -66.028 -9.483 -18.715 1.00 185.11 ? 115 SER A O 1 ATOM 677 C CB . SER A 1 88 ? -68.666 -11.038 -17.538 1.00 171.89 ? 115 SER A CB 1 ATOM 678 O OG . SER A 1 88 ? -69.041 -9.790 -18.067 1.00 181.83 ? 115 SER A OG 1 ATOM 679 N N . VAL A 1 89 ? -66.151 -11.568 -19.482 1.00 165.98 ? 116 VAL A N 1 ATOM 680 C CA . VAL A 1 89 ? -65.536 -11.183 -20.752 1.00 157.64 ? 116 VAL A CA 1 ATOM 681 C C . VAL A 1 89 ? -66.165 -11.981 -21.897 1.00 155.79 ? 116 VAL A C 1 ATOM 682 O O . VAL A 1 89 ? -66.438 -13.172 -21.755 1.00 157.22 ? 116 VAL A O 1 ATOM 683 C CB . VAL A 1 89 ? -63.998 -11.372 -20.726 1.00 147.48 ? 116 VAL A CB 1 ATOM 684 C CG1 . VAL A 1 89 ? -63.630 -12.780 -20.320 1.00 143.27 ? 116 VAL A CG1 1 ATOM 685 C CG2 . VAL A 1 89 ? -63.378 -11.000 -22.069 1.00 143.62 ? 116 VAL A CG2 1 ATOM 686 N N . SER A 1 90 ? -66.404 -11.322 -23.028 1.00 156.59 ? 117 SER A N 1 ATOM 687 C CA . SER A 1 90 ? -67.011 -11.987 -24.176 1.00 156.90 ? 117 SER A CA 1 ATOM 688 C C . SER A 1 90 ? -65.982 -12.376 -25.237 1.00 153.15 ? 117 SER A C 1 ATOM 689 O O . SER A 1 90 ? -64.925 -11.758 -25.348 1.00 157.19 ? 117 SER A O 1 ATOM 690 C CB . SER A 1 90 ? -68.108 -11.107 -24.787 1.00 167.95 ? 117 SER A CB 1 ATOM 691 O OG . SER A 1 90 ? -67.575 -10.006 -25.494 1.00 180.32 ? 117 SER A OG 1 ATOM 692 N N . THR A 1 91 ? -66.309 -13.405 -26.014 1.00 143.43 ? 118 THR A N 1 ATOM 693 C CA . THR A 1 91 ? -65.433 -13.907 -27.070 1.00 135.69 ? 118 THR A CA 1 ATOM 694 C C . THR A 1 91 ? -66.257 -14.767 -28.029 1.00 140.96 ? 118 THR A C 1 ATOM 695 O O . THR A 1 91 ? -67.283 -15.326 -27.642 1.00 147.23 ? 118 THR A O 1 ATOM 696 C CB . THR A 1 91 ? -64.246 -14.724 -26.501 1.00 123.20 ? 118 THR A CB 1 ATOM 697 O OG1 . THR A 1 91 ? -63.412 -15.178 -27.574 1.00 124.81 ? 118 THR A OG1 1 ATOM 698 C CG2 . THR A 1 91 ? -64.739 -15.924 -25.708 1.00 120.07 ? 118 THR A CG2 1 ATOM 699 N N . ARG A 1 92 ? -65.822 -14.860 -29.282 1.00 143.03 ? 119 ARG A N 1 ATOM 700 C CA . ARG A 1 92 ? -66.594 -15.582 -30.290 1.00 136.89 ? 119 ARG A CA 1 ATOM 701 C C . ARG A 1 92 ? -65.914 -16.873 -30.760 1.00 128.15 ? 119 ARG A C 1 ATOM 702 O O . ARG A 1 92 ? -64.691 -16.936 -30.874 1.00 131.27 ? 119 ARG A O 1 ATOM 703 C CB . ARG A 1 92 ? -66.876 -14.640 -31.465 1.00 144.84 ? 119 ARG A CB 1 ATOM 704 C CG . ARG A 1 92 ? -67.785 -13.481 -31.052 1.00 155.16 ? 119 ARG A CG 1 ATOM 705 C CD . ARG A 1 92 ? -68.166 -12.533 -32.190 1.00 161.51 ? 119 ARG A CD 1 ATOM 706 N NE . ARG A 1 92 ? -67.024 -11.816 -32.752 1.00 166.21 ? 119 ARG A NE 1 ATOM 707 C CZ . ARG A 1 92 ? -66.495 -10.720 -32.214 1.00 161.96 ? 119 ARG A CZ 1 ATOM 708 N NH1 . ARG A 1 92 ? -67.004 -10.213 -31.098 1.00 153.26 ? 119 ARG A NH1 1 ATOM 709 N NH2 . ARG A 1 92 ? -65.466 -10.122 -32.797 1.00 161.05 ? 119 ARG A NH2 1 ATOM 710 N N . LEU A 1 93 ? -66.725 -17.894 -31.036 1.00 123.62 ? 120 LEU A N 1 ATOM 711 C CA . LEU A 1 93 ? -66.241 -19.188 -31.526 1.00 124.31 ? 120 LEU A CA 1 ATOM 712 C C . LEU A 1 93 ? -66.831 -19.579 -32.888 1.00 122.72 ? 120 LEU A C 1 ATOM 713 O O . LEU A 1 93 ? -68.049 -19.566 -33.066 1.00 120.60 ? 120 LEU A O 1 ATOM 714 C CB . LEU A 1 93 ? -66.544 -20.286 -30.502 1.00 124.14 ? 120 LEU A CB 1 ATOM 715 C CG . LEU A 1 93 ? -66.399 -21.740 -30.968 1.00 110.33 ? 120 LEU A CG 1 ATOM 716 C CD1 . LEU A 1 93 ? -64.986 -22.030 -31.462 1.00 101.06 ? 120 LEU A CD1 1 ATOM 717 C CD2 . LEU A 1 93 ? -66.805 -22.718 -29.877 1.00 116.36 ? 120 LEU A CD2 1 ATOM 718 N N . THR A 1 94 ? -65.964 -19.920 -33.840 1.00 125.77 ? 121 THR A N 1 ATOM 719 C CA . THR A 1 94 ? -66.388 -20.415 -35.153 1.00 125.21 ? 121 THR A CA 1 ATOM 720 C C . THR A 1 94 ? -65.815 -21.818 -35.443 1.00 124.64 ? 121 THR A C 1 ATOM 721 O O . THR A 1 94 ? -64.640 -22.076 -35.188 1.00 124.03 ? 121 THR A O 1 ATOM 722 C CB . THR A 1 94 ? -65.964 -19.423 -36.266 1.00 122.99 ? 121 THR A CB 1 ATOM 723 O OG1 . THR A 1 94 ? -66.823 -18.275 -36.232 1.00 116.49 ? 121 THR A OG1 1 ATOM 724 C CG2 . THR A 1 94 ? -66.038 -20.061 -37.643 1.00 129.94 ? 121 THR A CG2 1 ATOM 725 N N . VAL A 1 95 ? -66.648 -22.720 -35.968 1.00 123.59 ? 122 VAL A N 1 ATOM 726 C CA . VAL A 1 95 ? -66.209 -24.066 -36.367 1.00 122.19 ? 122 VAL A CA 1 ATOM 727 C C . VAL A 1 95 ? -66.468 -24.379 -37.848 1.00 133.69 ? 122 VAL A C 1 ATOM 728 O O . VAL A 1 95 ? -67.553 -24.111 -38.364 1.00 132.27 ? 122 VAL A O 1 ATOM 729 C CB . VAL A 1 95 ? -66.896 -25.156 -35.508 1.00 118.08 ? 122 VAL A CB 1 ATOM 730 C CG1 . VAL A 1 95 ? -66.283 -26.524 -35.777 1.00 120.87 ? 122 VAL A CG1 1 ATOM 731 C CG2 . VAL A 1 95 ? -66.811 -24.809 -34.032 1.00 120.85 ? 122 VAL A CG2 1 ATOM 732 N N . LEU A 1 96 ? -65.467 -24.944 -38.524 1.00 144.50 ? 123 LEU A N 1 ATOM 733 C CA . LEU A 1 96 ? -65.587 -25.315 -39.938 1.00 148.33 ? 123 LEU A CA 1 ATOM 734 C C . LEU A 1 96 ? -65.628 -26.826 -40.209 1.00 147.94 ? 123 LEU A C 1 ATOM 735 O O . LEU A 1 96 ? -65.132 -27.628 -39.426 1.00 140.69 ? 123 LEU A O 1 ATOM 736 C CB . LEU A 1 96 ? -64.443 -24.696 -40.749 1.00 144.26 ? 123 LEU A CB 1 ATOM 737 C CG . LEU A 1 96 ? -64.314 -23.173 -40.736 1.00 146.44 ? 123 LEU A CG 1 ATOM 738 C CD1 . LEU A 1 96 ? -63.081 -22.741 -41.512 1.00 147.68 ? 123 LEU A CD1 1 ATOM 739 C CD2 . LEU A 1 96 ? -65.564 -22.531 -41.320 1.00 139.86 ? 123 LEU A CD2 1 ATOM 740 N N . ARG A 1 97 ? -66.200 -27.162 -41.364 1.00 154.48 ? 124 ARG A N 1 ATOM 741 C CA . ARG A 1 97 ? -66.196 -28.483 -42.009 1.00 153.93 ? 124 ARG A CA 1 ATOM 742 C C . ARG A 1 97 ? -65.027 -28.558 -42.990 1.00 157.84 ? 124 ARG A C 1 ATOM 743 O O . ARG A 1 97 ? -64.606 -27.536 -43.517 1.00 164.70 ? 124 ARG A O 1 ATOM 744 C CB . ARG A 1 97 ? -67.512 -28.768 -42.721 1.00 148.14 ? 124 ARG A CB 1 ATOM 745 C CG . ARG A 1 97 ? -68.717 -28.067 -42.133 1.00 146.82 ? 124 ARG A CG 1 ATOM 746 C CD . ARG A 1 97 ? -69.896 -28.235 -43.054 1.00 139.19 ? 124 ARG A CD 1 ATOM 747 N NE . ARG A 1 97 ? -69.789 -29.524 -43.726 1.00 144.72 ? 124 ARG A NE 1 ATOM 748 C CZ . ARG A 1 97 ? -70.349 -30.641 -43.277 1.00 144.65 ? 124 ARG A CZ 1 ATOM 749 N NH1 . ARG A 1 97 ? -71.034 -30.619 -42.143 1.00 140.39 ? 124 ARG A NH1 1 ATOM 750 N NH2 . ARG A 1 97 ? -70.195 -31.781 -43.937 1.00 148.60 ? 124 ARG A NH2 1 ATOM 751 N N . GLU A 1 98 ? -64.450 -29.735 -43.201 1.00 154.18 ? 125 GLU A N 1 ATOM 752 C CA . GLU A 1 98 ? -63.293 -29.795 -44.088 1.00 155.69 ? 125 GLU A CA 1 ATOM 753 C C . GLU A 1 98 ? -63.587 -29.646 -45.594 1.00 165.93 ? 125 GLU A C 1 ATOM 754 O O . GLU A 1 98 ? -62.670 -29.376 -46.372 1.00 163.45 ? 125 GLU A O 1 ATOM 755 C CB . GLU A 1 98 ? -62.609 -31.158 -43.913 1.00 155.07 ? 125 GLU A CB 1 ATOM 756 C CG . GLU A 1 98 ? -63.597 -32.354 -43.906 1.00 153.24 ? 125 GLU A CG 1 ATOM 757 C CD . GLU A 1 98 ? -64.315 -32.605 -42.591 1.00 143.58 ? 125 GLU A CD 1 ATOM 758 O OE1 . GLU A 1 98 ? -63.976 -33.592 -41.906 1.00 147.70 ? 125 GLU A OE1 1 ATOM 759 O OE2 . GLU A 1 98 ? -65.233 -31.824 -42.257 1.00 138.63 ? 125 GLU A OE2 1 ATOM 760 N N . ASP A 1 99 ? -64.844 -29.815 -46.004 1.00 170.78 ? 126 ASP A N 1 ATOM 761 C CA . ASP A 1 99 ? -65.359 -29.370 -47.316 1.00 163.07 ? 126 ASP A CA 1 ATOM 762 C C . ASP A 1 99 ? -65.182 -27.891 -47.733 1.00 153.18 ? 126 ASP A C 1 ATOM 763 O O . ASP A 1 99 ? -65.603 -27.503 -48.824 1.00 134.24 ? 126 ASP A O 1 ATOM 764 C CB . ASP A 1 99 ? -66.836 -29.762 -47.439 1.00 151.09 ? 126 ASP A CB 1 ATOM 765 C CG . ASP A 1 99 ? -67.135 -31.116 -46.810 1.00 147.23 ? 126 ASP A CG 1 ATOM 766 O OD1 . ASP A 1 99 ? -66.373 -31.552 -45.921 1.00 148.96 ? 126 ASP A OD1 1 ATOM 767 O OD2 . ASP A 1 99 ? -68.112 -31.767 -47.238 1.00 146.56 ? 126 ASP A OD2 1 ATOM 768 N N . GLN A 1 100 ? -64.620 -27.064 -46.859 1.00 161.25 ? 127 GLN A N 1 ATOM 769 C CA . GLN A 1 100 ? -64.469 -25.627 -47.121 1.00 163.30 ? 127 GLN A CA 1 ATOM 770 C C . GLN A 1 100 ? -63.340 -25.098 -46.224 1.00 166.58 ? 127 GLN A C 1 ATOM 771 O O . GLN A 1 100 ? -63.371 -23.975 -45.718 1.00 168.02 ? 127 GLN A O 1 ATOM 772 C CB . GLN A 1 100 ? -65.803 -24.859 -46.985 1.00 165.01 ? 127 GLN A CB 1 ATOM 773 C CG . GLN A 1 100 ? -66.300 -24.459 -45.612 1.00 174.72 ? 127 GLN A CG 1 ATOM 774 C CD . GLN A 1 100 ? -66.396 -25.614 -44.669 1.00 169.11 ? 127 GLN A CD 1 ATOM 775 O OE1 . GLN A 1 100 ? -67.250 -26.488 -44.816 1.00 158.44 ? 127 GLN A OE1 1 ATOM 776 N NE2 . GLN A 1 100 ? -65.527 -25.620 -43.671 1.00 170.88 ? 127 GLN A NE2 1 ATOM 777 N N . ILE A 1 101 ? -62.310 -25.929 -46.083 1.00 157.41 ? 128 ILE A N 1 ATOM 778 C CA . ILE A 1 101 ? -61.095 -25.522 -45.400 1.00 150.63 ? 128 ILE A CA 1 ATOM 779 C C . ILE A 1 101 ? -60.361 -24.683 -46.424 1.00 153.70 ? 128 ILE A C 1 ATOM 780 O O . ILE A 1 101 ? -60.041 -25.154 -47.515 1.00 157.95 ? 128 ILE A O 1 ATOM 781 C CB . ILE A 1 101 ? -60.219 -26.742 -44.988 1.00 147.19 ? 128 ILE A CB 1 ATOM 782 C CG1 . ILE A 1 101 ? -60.685 -27.366 -43.671 1.00 144.54 ? 128 ILE A CG1 1 ATOM 783 C CG2 . ILE A 1 101 ? -58.736 -26.374 -44.927 1.00 150.36 ? 128 ILE A CG2 1 ATOM 784 C CD1 . ILE A 1 101 ? -59.928 -28.644 -43.309 1.00 137.01 ? 128 ILE A CD1 1 ATOM 785 N N . PRO A 1 102 ? -60.118 -23.409 -46.071 1.00 151.89 ? 129 PRO A N 1 ATOM 786 C CA . PRO A 1 102 ? -59.513 -22.434 -46.981 1.00 160.61 ? 129 PRO A CA 1 ATOM 787 C C . PRO A 1 102 ? -58.165 -22.895 -47.490 1.00 160.84 ? 129 PRO A C 1 ATOM 788 O O . PRO A 1 102 ? -57.466 -23.640 -46.800 1.00 152.10 ? 129 PRO A O 1 ATOM 789 C CB . PRO A 1 102 ? -59.361 -21.181 -46.110 1.00 154.84 ? 129 PRO A CB 1 ATOM 790 C CG . PRO A 1 102 ? -60.331 -21.365 -44.994 1.00 143.28 ? 129 PRO A CG 1 ATOM 791 C CD . PRO A 1 102 ? -60.377 -22.835 -44.739 1.00 143.66 ? 129 PRO A CD 1 ATOM 792 N N . ARG A 1 103 ? -57.812 -22.466 -48.695 1.00 164.13 ? 130 ARG A N 1 ATOM 793 C CA . ARG A 1 103 ? -56.457 -22.658 -49.158 1.00 160.49 ? 130 ARG A CA 1 ATOM 794 C C . ARG A 1 103 ? -55.605 -21.823 -48.217 1.00 152.07 ? 130 ARG A C 1 ATOM 795 O O . ARG A 1 103 ? -55.873 -20.640 -48.003 1.00 148.07 ? 130 ARG A O 1 ATOM 796 C CB . ARG A 1 103 ? -56.341 -22.239 -50.625 1.00 168.84 ? 130 ARG A CB 1 ATOM 797 C CG . ARG A 1 103 ? -55.223 -22.884 -51.415 1.00 176.07 ? 130 ARG A CG 1 ATOM 798 C CD . ARG A 1 103 ? -55.229 -22.341 -52.837 1.00 185.71 ? 130 ARG A CD 1 ATOM 799 N NE . ARG A 1 103 ? -56.401 -22.829 -53.567 1.00 192.35 ? 130 ARG A NE 1 ATOM 800 C CZ . ARG A 1 103 ? -56.811 -22.364 -54.744 1.00 195.25 ? 130 ARG A CZ 1 ATOM 801 N NH1 . ARG A 1 103 ? -56.149 -21.382 -55.339 1.00 193.43 ? 130 ARG A NH1 1 ATOM 802 N NH2 . ARG A 1 103 ? -57.888 -22.878 -55.324 1.00 190.13 ? 130 ARG A NH2 1 ATOM 803 N N . GLY A 1 104 ? -54.581 -22.448 -47.655 1.00 147.42 ? 131 GLY A N 1 ATOM 804 C CA . GLY A 1 104 ? -53.657 -21.763 -46.779 1.00 145.09 ? 131 GLY A CA 1 ATOM 805 C C . GLY A 1 104 ? -54.117 -21.909 -45.335 1.00 134.10 ? 131 GLY A C 1 ATOM 806 O O . GLY A 1 104 ? -54.049 -20.960 -44.555 1.00 124.28 ? 131 GLY A O 1 ATOM 807 N N . PHE A 1 105 ? -54.599 -23.095 -44.976 1.00 138.22 ? 132 PHE A N 1 ATOM 808 C CA . PHE A 1 105 ? -55.064 -23.354 -43.612 1.00 135.45 ? 132 PHE A CA 1 ATOM 809 C C . PHE A 1 105 ? -54.141 -24.336 -42.914 1.00 136.89 ? 132 PHE A C 1 ATOM 810 O O . PHE A 1 105 ? -53.633 -25.257 -43.554 1.00 146.12 ? 132 PHE A O 1 ATOM 811 C CB . PHE A 1 105 ? -56.495 -23.901 -43.605 1.00 135.00 ? 132 PHE A CB 1 ATOM 812 C CG . PHE A 1 105 ? -57.052 -24.116 -42.223 1.00 125.13 ? 132 PHE A CG 1 ATOM 813 C CD1 . PHE A 1 105 ? -57.670 -23.087 -41.536 1.00 125.75 ? 132 PHE A CD1 1 ATOM 814 C CD2 . PHE A 1 105 ? -56.943 -25.352 -41.606 1.00 119.27 ? 132 PHE A CD2 1 ATOM 815 C CE1 . PHE A 1 105 ? -58.172 -23.292 -40.266 1.00 118.07 ? 132 PHE A CE1 1 ATOM 816 C CE2 . PHE A 1 105 ? -57.439 -25.559 -40.337 1.00 110.67 ? 132 PHE A CE2 1 ATOM 817 C CZ . PHE A 1 105 ? -58.054 -24.527 -39.665 1.00 107.84 ? 132 PHE A CZ 1 ATOM 818 N N . PRO A 1 106 ? -53.893 -24.128 -41.608 1.00 125.08 ? 133 PRO A N 1 ATOM 819 C CA . PRO A 1 106 ? -52.853 -24.981 -41.031 1.00 121.17 ? 133 PRO A CA 1 ATOM 820 C C . PRO A 1 106 ? -53.197 -26.471 -41.081 1.00 121.65 ? 133 PRO A C 1 ATOM 821 O O . PRO A 1 106 ? -54.349 -26.849 -40.874 1.00 123.04 ? 133 PRO A O 1 ATOM 822 C CB . PRO A 1 106 ? -52.783 -24.496 -39.584 1.00 121.66 ? 133 PRO A CB 1 ATOM 823 C CG . PRO A 1 106 ? -53.172 -23.054 -39.670 1.00 123.61 ? 133 PRO A CG 1 ATOM 824 C CD . PRO A 1 106 ? -54.247 -23.003 -40.722 1.00 121.23 ? 133 PRO A CD 1 ATOM 825 N N . THR A 1 107 ? -52.193 -27.299 -41.344 1.00 122.27 ? 134 THR A N 1 ATOM 826 C CA . THR A 1 107 ? -52.346 -28.749 -41.330 1.00 129.11 ? 134 THR A CA 1 ATOM 827 C C . THR A 1 107 ? -51.200 -29.366 -40.533 1.00 125.39 ? 134 THR A C 1 ATOM 828 O O . THR A 1 107 ? -50.071 -28.887 -40.631 1.00 120.43 ? 134 THR A O 1 ATOM 829 C CB . THR A 1 107 ? -52.387 -29.334 -42.760 1.00 135.09 ? 134 THR A CB 1 ATOM 830 O OG1 . THR A 1 107 ? -51.408 -28.682 -43.577 1.00 138.81 ? 134 THR A OG1 1 ATOM 831 C CG2 . THR A 1 107 ? -53.763 -29.129 -43.383 1.00 124.62 ? 134 THR A CG2 1 ATOM 832 N N . ILE A 1 108 ? -51.454 -30.405 -39.744 1.00 125.96 ? 135 ILE A N 1 ATOM 833 C CA . ILE A 1 108 ? -50.332 -31.060 -39.082 1.00 124.35 ? 135 ILE A CA 1 ATOM 834 C C . ILE A 1 108 ? -49.772 -32.141 -40.015 1.00 132.45 ? 135 ILE A C 1 ATOM 835 O O . ILE A 1 108 ? -50.480 -33.069 -40.414 1.00 140.92 ? 135 ILE A O 1 ATOM 836 C CB . ILE A 1 108 ? -50.742 -31.671 -37.725 1.00 122.98 ? 135 ILE A CB 1 ATOM 837 C CG1 . ILE A 1 108 ? -51.316 -30.589 -36.803 1.00 109.79 ? 135 ILE A CG1 1 ATOM 838 C CG2 . ILE A 1 108 ? -49.555 -32.349 -37.060 1.00 126.90 ? 135 ILE A CG2 1 ATOM 839 C CD1 . ILE A 1 108 ? -50.330 -29.492 -36.446 1.00 109.58 ? 135 ILE A CD1 1 ATOM 840 N N . ASP A 1 109 ? -48.497 -31.998 -40.362 1.00 126.54 ? 136 ASP A N 1 ATOM 841 C CA . ASP A 1 109 ? -47.789 -32.948 -41.218 1.00 117.39 ? 136 ASP A CA 1 ATOM 842 C C . ASP A 1 109 ? -47.089 -34.027 -40.403 1.00 114.17 ? 136 ASP A C 1 ATOM 843 O O . ASP A 1 109 ? -46.883 -35.150 -40.862 1.00 114.45 ? 136 ASP A O 1 ATOM 844 C CB . ASP A 1 109 ? -46.774 -32.210 -42.095 1.00 117.80 ? 136 ASP A CB 1 ATOM 845 C CG . ASP A 1 109 ? -47.417 -31.144 -42.965 1.00 120.98 ? 136 ASP A CG 1 ATOM 846 O OD1 . ASP A 1 109 ? -48.396 -31.461 -43.673 1.00 125.62 ? 136 ASP A OD1 1 ATOM 847 O OD2 . ASP A 1 109 ? -46.948 -29.986 -42.936 1.00 117.44 ? 136 ASP A OD2 1 ATOM 848 N N . MET A 1 110 ? -46.744 -33.653 -39.178 1.00 117.49 ? 137 MET A N 1 ATOM 849 C CA . MET A 1 110 ? -46.181 -34.543 -38.175 1.00 118.48 ? 137 MET A CA 1 ATOM 850 C C . MET A 1 110 ? -46.227 -33.921 -36.793 1.00 124.41 ? 137 MET A C 1 ATOM 851 O O . MET A 1 110 ? -45.883 -32.753 -36.620 1.00 125.57 ? 137 MET A O 1 ATOM 852 C CB . MET A 1 110 ? -44.732 -34.902 -38.519 1.00 116.71 ? 137 MET A CB 1 ATOM 853 C CG . MET A 1 110 ? -44.124 -35.957 -37.602 1.00 109.38 ? 137 MET A CG 1 ATOM 854 S SD . MET A 1 110 ? -44.681 -37.655 -37.801 1.00 135.91 ? 137 MET A SD 1 ATOM 855 C CE . MET A 1 110 ? -43.247 -38.522 -37.167 1.00 110.69 ? 137 MET A CE 1 ATOM 856 N N . GLY A 1 111 ? -46.647 -34.703 -35.807 1.00 128.80 ? 138 GLY A N 1 ATOM 857 C CA . GLY A 1 111 ? -46.886 -34.164 -34.487 1.00 121.01 ? 138 GLY A CA 1 ATOM 858 C C . GLY A 1 111 ? -45.877 -34.772 -33.534 1.00 117.66 ? 138 GLY A C 1 ATOM 859 O O . GLY A 1 111 ? -45.186 -35.731 -33.880 1.00 121.33 ? 138 GLY A O 1 ATOM 860 N N . PRO A 1 112 ? -45.770 -34.195 -32.332 1.00 105.38 ? 139 PRO A N 1 ATOM 861 C CA . PRO A 1 112 ? -44.837 -34.615 -31.279 1.00 97.92 ? 139 PRO A CA 1 ATOM 862 C C . PRO A 1 112 ? -44.938 -36.097 -30.956 1.00 96.72 ? 139 PRO A C 1 ATOM 863 O O . PRO A 1 112 ? -46.020 -36.664 -31.079 1.00 102.74 ? 139 PRO A O 1 ATOM 864 C CB . PRO A 1 112 ? -45.265 -33.773 -30.074 1.00 102.87 ? 139 PRO A CB 1 ATOM 865 C CG . PRO A 1 112 ? -46.017 -32.619 -30.658 1.00 110.09 ? 139 PRO A CG 1 ATOM 866 C CD . PRO A 1 112 ? -46.699 -33.151 -31.867 1.00 102.14 ? 139 PRO A CD 1 ATOM 867 N N . GLN A 1 113 ? -43.839 -36.719 -30.544 1.00 97.79 ? 140 GLN A N 1 ATOM 868 C CA . GLN A 1 113 ? -43.892 -38.139 -30.245 1.00 102.46 ? 140 GLN A CA 1 ATOM 869 C C . GLN A 1 113 ? -43.453 -38.372 -28.806 1.00 96.45 ? 140 GLN A C 1 ATOM 870 O O . GLN A 1 113 ? -42.842 -37.503 -28.185 1.00 96.09 ? 140 GLN A O 1 ATOM 871 C CB . GLN A 1 113 ? -42.998 -38.930 -31.210 1.00 102.60 ? 140 GLN A CB 1 ATOM 872 C CG . GLN A 1 113 ? -43.437 -38.874 -32.666 1.00 114.66 ? 140 GLN A CG 1 ATOM 873 C CD . GLN A 1 113 ? -44.860 -39.357 -32.874 1.00 117.70 ? 140 GLN A CD 1 ATOM 874 O OE1 . GLN A 1 113 ? -45.314 -40.293 -32.215 1.00 123.11 ? 140 GLN A OE1 1 ATOM 875 N NE2 . GLN A 1 113 ? -45.575 -38.711 -33.789 1.00 113.10 ? 140 GLN A NE2 1 ATOM 876 N N . LEU A 1 114 ? -43.800 -39.539 -28.277 1.00 91.23 ? 141 LEU A N 1 ATOM 877 C CA . LEU A 1 114 ? -43.485 -39.890 -26.900 1.00 75.77 ? 141 LEU A CA 1 ATOM 878 C C . LEU A 1 114 ? -41.978 -39.828 -26.681 1.00 69.98 ? 141 LEU A C 1 ATOM 879 O O . LEU A 1 114 ? -41.217 -40.466 -27.407 1.00 85.78 ? 141 LEU A O 1 ATOM 880 C CB . LEU A 1 114 ? -44.036 -41.272 -26.556 1.00 77.82 ? 141 LEU A CB 1 ATOM 881 C CG . LEU A 1 114 ? -45.533 -41.413 -26.843 1.00 84.40 ? 141 LEU A CG 1 ATOM 882 C CD1 . LEU A 1 114 ? -45.813 -42.649 -27.689 1.00 84.98 ? 141 LEU A CD1 1 ATOM 883 C CD2 . LEU A 1 114 ? -46.353 -41.444 -25.558 1.00 82.46 ? 141 LEU A CD2 1 ATOM 884 N N . LYS A 1 115 ? -41.542 -39.075 -25.681 1.00 64.76 ? 142 LYS A N 1 ATOM 885 C CA . LYS A 1 115 ? -40.115 -38.896 -25.444 1.00 71.78 ? 142 LYS A CA 1 ATOM 886 C C . LYS A 1 115 ? -39.808 -39.166 -23.983 1.00 76.20 ? 142 LYS A C 1 ATOM 887 O O . LYS A 1 115 ? -40.592 -38.822 -23.102 1.00 86.79 ? 142 LYS A O 1 ATOM 888 C CB . LYS A 1 115 ? -39.644 -37.496 -25.842 1.00 70.04 ? 142 LYS A CB 1 ATOM 889 C CG . LYS A 1 115 ? -38.146 -37.440 -26.125 1.00 67.92 ? 142 LYS A CG 1 ATOM 890 C CD . LYS A 1 115 ? -37.715 -36.151 -26.793 1.00 67.31 ? 142 LYS A CD 1 ATOM 891 C CE . LYS A 1 115 ? -36.541 -35.525 -26.041 1.00 71.51 ? 142 LYS A CE 1 ATOM 892 N NZ . LYS A 1 115 ? -35.246 -36.221 -26.295 1.00 55.59 ? 142 LYS A NZ 1 ATOM 893 N N . VAL A 1 116 ? -38.656 -39.772 -23.726 1.00 71.92 ? 143 VAL A N 1 ATOM 894 C CA . VAL A 1 116 ? -38.281 -40.162 -22.375 1.00 74.18 ? 143 VAL A CA 1 ATOM 895 C C . VAL A 1 116 ? -36.879 -39.651 -22.079 1.00 80.89 ? 143 VAL A C 1 ATOM 896 O O . VAL A 1 116 ? -35.881 -40.182 -22.559 1.00 87.19 ? 143 VAL A O 1 ATOM 897 C CB . VAL A 1 116 ? -38.338 -41.698 -22.176 1.00 75.26 ? 143 VAL A CB 1 ATOM 898 C CG1 . VAL A 1 116 ? -37.828 -42.078 -20.797 1.00 77.79 ? 143 VAL A CG1 1 ATOM 899 C CG2 . VAL A 1 116 ? -39.752 -42.216 -22.363 1.00 80.93 ? 143 VAL A CG2 1 ATOM 900 N N . VAL A 1 117 ? -36.848 -38.585 -21.289 1.00 88.55 ? 144 VAL A N 1 ATOM 901 C CA . VAL A 1 117 ? -35.639 -37.899 -20.863 1.00 95.34 ? 144 VAL A CA 1 ATOM 902 C C . VAL A 1 117 ? -35.476 -38.197 -19.385 1.00 97.76 ? 144 VAL A C 1 ATOM 903 O O . VAL A 1 117 ? -36.453 -38.515 -18.706 1.00 97.48 ? 144 VAL A O 1 ATOM 904 C CB . VAL A 1 117 ? -35.709 -36.369 -21.104 1.00 98.55 ? 144 VAL A CB 1 ATOM 905 C CG1 . VAL A 1 117 ? -36.681 -35.709 -20.130 1.00 93.94 ? 144 VAL A CG1 1 ATOM 906 C CG2 . VAL A 1 117 ? -34.323 -35.734 -21.010 1.00 102.52 ? 144 VAL A CG2 1 ATOM 907 N N . GLU A 1 118 ? -34.256 -38.134 -18.872 1.00 101.45 ? 145 GLU A N 1 ATOM 908 C CA . GLU A 1 118 ? -34.128 -38.302 -17.445 1.00 108.30 ? 145 GLU A CA 1 ATOM 909 C C . GLU A 1 118 ? -34.145 -36.957 -16.778 1.00 114.30 ? 145 GLU A C 1 ATOM 910 O O . GLU A 1 118 ? -33.991 -35.920 -17.424 1.00 119.30 ? 145 GLU A O 1 ATOM 911 C CB . GLU A 1 118 ? -32.808 -38.934 -17.028 1.00 118.01 ? 145 GLU A CB 1 ATOM 912 C CG . GLU A 1 118 ? -31.629 -38.130 -17.550 1.00 119.47 ? 145 GLU A CG 1 ATOM 913 C CD . GLU A 1 118 ? -30.319 -38.505 -16.906 1.00 122.80 ? 145 GLU A CD 1 ATOM 914 O OE1 . GLU A 1 118 ? -30.122 -39.684 -16.593 1.00 125.14 ? 145 GLU A OE1 1 ATOM 915 O OE2 . GLU A 1 118 ? -29.473 -37.607 -16.714 1.00 126.50 ? 145 GLU A OE2 1 ATOM 916 N N . ARG A 1 119 ? -34.384 -36.997 -15.475 1.00 116.34 ? 146 ARG A N 1 ATOM 917 C CA . ARG A 1 119 ? -34.600 -35.806 -14.690 1.00 116.86 ? 146 ARG A CA 1 ATOM 918 C C . ARG A 1 119 ? -33.297 -35.014 -14.779 1.00 110.28 ? 146 ARG A C 1 ATOM 919 O O . ARG A 1 119 ? -32.221 -35.616 -14.785 1.00 105.58 ? 146 ARG A O 1 ATOM 920 C CB . ARG A 1 119 ? -34.969 -36.175 -13.254 1.00 120.35 ? 146 ARG A CB 1 ATOM 921 C CG . ARG A 1 119 ? -35.453 -35.041 -12.382 1.00 116.09 ? 146 ARG A CG 1 ATOM 922 C CD . ARG A 1 119 ? -35.811 -35.577 -11.010 1.00 115.77 ? 146 ARG A CD 1 ATOM 923 N NE . ARG A 1 119 ? -34.718 -36.375 -10.464 1.00 125.52 ? 146 ARG A NE 1 ATOM 924 C CZ . ARG A 1 119 ? -33.634 -35.873 -9.883 1.00 131.81 ? 146 ARG A CZ 1 ATOM 925 N NH1 . ARG A 1 119 ? -33.482 -34.561 -9.775 1.00 144.44 ? 146 ARG A NH1 1 ATOM 926 N NH2 . ARG A 1 119 ? -32.697 -36.688 -9.417 1.00 130.36 ? 146 ARG A NH2 1 ATOM 927 N N . THR A 1 120 ? -33.386 -33.689 -14.878 1.00 108.09 ? 147 THR A N 1 ATOM 928 C CA . THR A 1 120 ? -32.206 -32.817 -14.964 1.00 110.95 ? 147 THR A CA 1 ATOM 929 C C . THR A 1 120 ? -31.407 -33.019 -16.261 1.00 112.10 ? 147 THR A C 1 ATOM 930 O O . THR A 1 120 ? -30.189 -32.850 -16.276 1.00 116.60 ? 147 THR A O 1 ATOM 931 C CB . THR A 1 120 ? -31.252 -32.988 -13.749 1.00 124.11 ? 147 THR A CB 1 ATOM 932 O OG1 . THR A 1 120 ? -30.503 -34.204 -13.884 1.00 120.54 ? 147 THR A OG1 1 ATOM 933 C CG2 . THR A 1 120 ? -32.035 -33.015 -12.439 1.00 128.94 ? 147 THR A CG2 1 ATOM 934 N N . ARG A 1 121 ? -32.099 -33.365 -17.344 1.00 112.66 ? 148 ARG A N 1 ATOM 935 C CA . ARG A 1 121 ? -31.469 -33.496 -18.658 1.00 114.93 ? 148 ARG A CA 1 ATOM 936 C C . ARG A 1 121 ? -32.306 -32.692 -19.649 1.00 107.32 ? 148 ARG A C 1 ATOM 937 O O . ARG A 1 121 ? -33.497 -32.488 -19.423 1.00 107.89 ? 148 ARG A O 1 ATOM 938 C CB . ARG A 1 121 ? -31.355 -34.967 -19.085 1.00 117.79 ? 148 ARG A CB 1 ATOM 939 C CG . ARG A 1 121 ? -30.586 -35.190 -20.387 1.00 112.59 ? 148 ARG A CG 1 ATOM 940 C CD . ARG A 1 121 ? -29.316 -34.354 -20.398 1.00 116.64 ? 148 ARG A CD 1 ATOM 941 N NE . ARG A 1 121 ? -28.526 -34.512 -21.615 1.00 116.93 ? 148 ARG A NE 1 ATOM 942 C CZ . ARG A 1 121 ? -27.769 -33.550 -22.132 1.00 122.01 ? 148 ARG A CZ 1 ATOM 943 N NH1 . ARG A 1 121 ? -27.714 -32.362 -21.542 1.00 114.02 ? 148 ARG A NH1 1 ATOM 944 N NH2 . ARG A 1 121 ? -27.071 -33.770 -23.238 1.00 137.27 ? 148 ARG A NH2 1 ATOM 945 N N . THR A 1 122 ? -31.700 -32.248 -20.747 1.00 105.72 ? 149 THR A N 1 ATOM 946 C CA . THR A 1 122 ? -32.412 -31.387 -21.679 1.00 109.71 ? 149 THR A CA 1 ATOM 947 C C . THR A 1 122 ? -33.296 -32.213 -22.611 1.00 112.68 ? 149 THR A C 1 ATOM 948 O O . THR A 1 122 ? -32.810 -33.036 -23.389 1.00 110.83 ? 149 THR A O 1 ATOM 949 C CB . THR A 1 122 ? -31.415 -30.551 -22.516 1.00 117.95 ? 149 THR A CB 1 ATOM 950 O OG1 . THR A 1 122 ? -30.605 -29.748 -21.647 1.00 120.18 ? 149 THR A OG1 1 ATOM 951 C CG2 . THR A 1 122 ? -32.144 -29.661 -23.515 1.00 122.07 ? 149 THR A CG2 1 ATOM 952 N N . ALA A 1 123 ? -34.604 -31.986 -22.514 1.00 114.06 ? 150 ALA A N 1 ATOM 953 C CA . ALA A 1 123 ? -35.577 -32.609 -23.406 1.00 111.01 ? 150 ALA A CA 1 ATOM 954 C C . ALA A 1 123 ? -36.085 -31.657 -24.488 1.00 105.27 ? 150 ALA A C 1 ATOM 955 O O . ALA A 1 123 ? -36.324 -30.482 -24.220 1.00 103.40 ? 150 ALA A O 1 ATOM 956 C CB . ALA A 1 123 ? -36.753 -33.147 -22.599 1.00 102.64 ? 150 ALA A CB 1 ATOM 957 N N . THR A 1 124 ? -36.254 -32.172 -25.704 1.00 101.29 ? 151 THR A N 1 ATOM 958 C CA . THR A 1 124 ? -36.733 -31.372 -26.830 1.00 104.31 ? 151 THR A CA 1 ATOM 959 C C . THR A 1 124 ? -37.966 -32.028 -27.461 1.00 112.59 ? 151 THR A C 1 ATOM 960 O O . THR A 1 124 ? -37.928 -33.207 -27.804 1.00 121.41 ? 151 THR A O 1 ATOM 961 C CB . THR A 1 124 ? -35.638 -31.180 -27.903 1.00 113.47 ? 151 THR A CB 1 ATOM 962 O OG1 . THR A 1 124 ? -34.452 -30.666 -27.286 1.00 116.14 ? 151 THR A OG1 1 ATOM 963 C CG2 . THR A 1 124 ? -36.104 -30.198 -28.971 1.00 117.06 ? 151 THR A CG2 1 ATOM 964 N N . MET A 1 125 ? -39.054 -31.278 -27.620 1.00 109.90 ? 152 MET A N 1 ATOM 965 C CA . MET A 1 125 ? -40.212 -31.776 -28.370 1.00 111.99 ? 152 MET A CA 1 ATOM 966 C C . MET A 1 125 ? -40.304 -31.163 -29.759 1.00 114.45 ? 152 MET A C 1 ATOM 967 O O . MET A 1 125 ? -40.002 -29.999 -29.943 1.00 107.94 ? 152 MET A O 1 ATOM 968 C CB . MET A 1 125 ? -41.512 -31.527 -27.602 1.00 98.30 ? 152 MET A CB 1 ATOM 969 C CG . MET A 1 125 ? -41.483 -32.024 -26.174 1.00 101.77 ? 152 MET A CG 1 ATOM 970 S SD . MET A 1 125 ? -41.480 -33.828 -26.153 1.00 89.14 ? 152 MET A SD 1 ATOM 971 C CE . MET A 1 125 ? -43.174 -34.171 -26.628 1.00 101.07 ? 152 MET A CE 1 ATOM 972 N N . LEU A 1 126 ? -40.732 -31.962 -30.730 1.00 121.41 ? 153 LEU A N 1 ATOM 973 C CA . LEU A 1 126 ? -40.706 -31.562 -32.134 1.00 121.70 ? 153 LEU A CA 1 ATOM 974 C C . LEU A 1 126 ? -42.111 -31.492 -32.723 1.00 115.52 ? 153 LEU A C 1 ATOM 975 O O . LEU A 1 126 ? -43.026 -32.163 -32.250 1.00 115.03 ? 153 LEU A O 1 ATOM 976 C CB . LEU A 1 126 ? -39.838 -32.532 -32.948 1.00 130.12 ? 153 LEU A CB 1 ATOM 977 C CG . LEU A 1 126 ? -39.858 -32.456 -34.480 1.00 121.46 ? 153 LEU A CG 1 ATOM 978 C CD1 . LEU A 1 126 ? -39.138 -31.215 -35.001 1.00 106.12 ? 153 LEU A CD1 1 ATOM 979 C CD2 . LEU A 1 126 ? -39.283 -33.714 -35.094 1.00 111.02 ? 153 LEU A CD2 1 ATOM 980 N N . CYS A 1 127 ? -42.277 -30.663 -33.748 1.00 113.96 ? 154 CYS A N 1 ATOM 981 C CA . CYS A 1 127 ? -43.561 -30.503 -34.418 1.00 122.00 ? 154 CYS A CA 1 ATOM 982 C C . CYS A 1 127 ? -43.422 -30.094 -35.878 1.00 125.37 ? 154 CYS A C 1 ATOM 983 O O . CYS A 1 127 ? -42.408 -29.524 -36.279 1.00 119.88 ? 154 CYS A O 1 ATOM 984 C CB . CYS A 1 127 ? -44.421 -29.471 -33.700 1.00 124.41 ? 154 CYS A CB 1 ATOM 985 S SG . CYS A 1 127 ? -46.134 -29.546 -34.227 1.00 131.79 ? 154 CYS A SG 1 ATOM 986 N N . ALA A 1 128 ? -44.441 -30.407 -36.674 1.00 127.68 ? 155 ALA A N 1 ATOM 987 C CA . ALA A 1 128 ? -44.495 -29.937 -38.051 1.00 121.59 ? 155 ALA A CA 1 ATOM 988 C C . ALA A 1 128 ? -45.892 -29.494 -38.486 1.00 120.49 ? 155 ALA A C 1 ATOM 989 O O . ALA A 1 128 ? -46.842 -30.278 -38.442 1.00 117.97 ? 155 ALA A O 1 ATOM 990 C CB . ALA A 1 128 ? -43.981 -31.023 -38.994 1.00 116.12 ? 155 ALA A CB 1 ATOM 991 N N . ALA A 1 129 ? -46.010 -28.232 -38.889 1.00 122.03 ? 156 ALA A N 1 ATOM 992 C CA . ALA A 1 129 ? -47.285 -27.686 -39.325 1.00 122.07 ? 156 ALA A CA 1 ATOM 993 C C . ALA A 1 129 ? -46.995 -26.768 -40.505 1.00 117.37 ? 156 ALA A C 1 ATOM 994 O O . ALA A 1 129 ? -45.942 -26.133 -40.550 1.00 118.00 ? 156 ALA A O 1 ATOM 995 C CB . ALA A 1 129 ? -47.970 -26.932 -38.201 1.00 126.64 ? 156 ALA A CB 1 ATOM 996 N N . SER A 1 130 ? -47.922 -26.681 -41.450 1.00 111.29 ? 157 SER A N 1 ATOM 997 C CA . SER A 1 130 ? -47.795 -25.723 -42.541 1.00 115.14 ? 157 SER A CA 1 ATOM 998 C C . SER A 1 130 ? -49.067 -24.915 -42.735 1.00 118.93 ? 157 SER A C 1 ATOM 999 O O . SER A 1 130 ? -50.096 -25.240 -42.162 1.00 117.39 ? 157 SER A O 1 ATOM 1000 C CB . SER A 1 130 ? -47.434 -26.447 -43.842 1.00 121.44 ? 157 SER A CB 1 ATOM 1001 O OG . SER A 1 130 ? -47.198 -27.823 -43.613 1.00 120.22 ? 157 SER A OG 1 ATOM 1002 N N . GLY A 1 131 ? -48.983 -23.865 -43.545 1.00 119.81 ? 158 GLY A N 1 ATOM 1003 C CA . GLY A 1 131 ? -50.125 -23.019 -43.831 1.00 116.53 ? 158 GLY A CA 1 ATOM 1004 C C . GLY A 1 131 ? -49.727 -21.753 -44.558 1.00 114.25 ? 158 GLY A C 1 ATOM 1005 O O . GLY A 1 131 ? -48.550 -21.384 -44.572 1.00 113.42 ? 158 GLY A O 1 ATOM 1006 N N . ASN A 1 132 ? -50.700 -21.084 -45.169 1.00 122.46 ? 159 ASN A N 1 ATOM 1007 C CA . ASN A 1 132 ? -50.463 -19.788 -45.793 1.00 134.81 ? 159 ASN A CA 1 ATOM 1008 C C . ASN A 1 132 ? -51.566 -18.793 -45.399 1.00 138.94 ? 159 ASN A C 1 ATOM 1009 O O . ASN A 1 132 ? -52.714 -18.959 -45.804 1.00 143.05 ? 159 ASN A O 1 ATOM 1010 C CB . ASN A 1 132 ? -50.376 -19.949 -47.316 1.00 134.83 ? 159 ASN A CB 1 ATOM 1011 C CG . ASN A 1 132 ? -50.476 -18.632 -48.057 1.00 132.47 ? 159 ASN A CG 1 ATOM 1012 O OD1 . ASN A 1 132 ? -51.274 -18.491 -48.987 1.00 127.70 ? 159 ASN A OD1 1 ATOM 1013 N ND2 . ASN A 1 132 ? -49.655 -17.665 -47.666 1.00 133.87 ? 159 ASN A ND2 1 ATOM 1014 N N . PRO A 1 133 ? -51.238 -17.748 -44.618 1.00 133.10 ? 160 PRO A N 1 ATOM 1015 C CA . PRO A 1 133 ? -49.958 -17.295 -44.060 1.00 127.91 ? 160 PRO A CA 1 ATOM 1016 C C . PRO A 1 133 ? -49.356 -18.282 -43.055 1.00 127.65 ? 160 PRO A C 1 ATOM 1017 O O . PRO A 1 133 ? -50.014 -19.239 -42.651 1.00 122.11 ? 160 PRO A O 1 ATOM 1018 C CB . PRO A 1 133 ? -50.322 -15.975 -43.361 1.00 112.55 ? 160 PRO A CB 1 ATOM 1019 C CG . PRO A 1 133 ? -51.779 -16.035 -43.157 1.00 117.76 ? 160 PRO A CG 1 ATOM 1020 C CD . PRO A 1 133 ? -52.319 -16.801 -44.314 1.00 124.95 ? 160 PRO A CD 1 ATOM 1021 N N . ASP A 1 134 ? -48.109 -18.025 -42.669 1.00 134.58 ? 161 ASP A N 1 ATOM 1022 C CA . ASP A 1 134 ? -47.340 -18.928 -41.816 1.00 130.87 ? 161 ASP A CA 1 ATOM 1023 C C . ASP A 1 134 ? -47.994 -19.109 -40.445 1.00 127.26 ? 161 ASP A C 1 ATOM 1024 O O . ASP A 1 134 ? -48.421 -18.137 -39.823 1.00 129.30 ? 161 ASP A O 1 ATOM 1025 C CB . ASP A 1 134 ? -45.911 -18.396 -41.656 1.00 129.33 ? 161 ASP A CB 1 ATOM 1026 C CG . ASP A 1 134 ? -45.005 -18.779 -42.816 1.00 123.64 ? 161 ASP A CG 1 ATOM 1027 O OD1 . ASP A 1 134 ? -45.249 -19.826 -43.448 1.00 128.47 ? 161 ASP A OD1 1 ATOM 1028 O OD2 . ASP A 1 134 ? -44.049 -18.025 -43.102 1.00 106.26 ? 161 ASP A OD2 1 ATOM 1029 N N . PRO A 1 135 ? -48.085 -20.367 -39.979 1.00 125.99 ? 162 PRO A N 1 ATOM 1030 C CA . PRO A 1 135 ? -48.761 -20.711 -38.718 1.00 126.72 ? 162 PRO A CA 1 ATOM 1031 C C . PRO A 1 135 ? -47.983 -20.320 -37.454 1.00 124.33 ? 162 PRO A C 1 ATOM 1032 O O . PRO A 1 135 ? -46.752 -20.371 -37.434 1.00 120.12 ? 162 PRO A O 1 ATOM 1033 C CB . PRO A 1 135 ? -48.904 -22.239 -38.806 1.00 123.30 ? 162 PRO A CB 1 ATOM 1034 C CG . PRO A 1 135 ? -47.857 -22.671 -39.786 1.00 121.43 ? 162 PRO A CG 1 ATOM 1035 C CD . PRO A 1 135 ? -47.761 -21.561 -40.779 1.00 123.87 ? 162 PRO A CD 1 ATOM 1036 N N . GLU A 1 136 ? -48.718 -19.926 -36.415 1.00 119.76 ? 163 GLU A N 1 ATOM 1037 C CA . GLU A 1 136 ? -48.160 -19.720 -35.078 1.00 116.60 ? 163 GLU A CA 1 ATOM 1038 C C . GLU A 1 136 ? -48.259 -20.980 -34.215 1.00 117.63 ? 163 GLU A C 1 ATOM 1039 O O . GLU A 1 136 ? -49.318 -21.601 -34.140 1.00 120.61 ? 163 GLU A O 1 ATOM 1040 C CB . GLU A 1 136 ? -48.878 -18.557 -34.385 1.00 113.48 ? 163 GLU A CB 1 ATOM 1041 C CG . GLU A 1 136 ? -47.948 -17.585 -33.688 1.00 118.45 ? 163 GLU A CG 1 ATOM 1042 C CD . GLU A 1 136 ? -47.391 -16.543 -34.639 1.00 126.34 ? 163 GLU A CD 1 ATOM 1043 O OE1 . GLU A 1 136 ? -47.931 -16.414 -35.760 1.00 125.51 ? 163 GLU A OE1 1 ATOM 1044 O OE2 . GLU A 1 136 ? -46.412 -15.859 -34.270 1.00 133.97 ? 163 GLU A OE2 1 ATOM 1045 N N . ILE A 1 137 ? -47.163 -21.347 -33.553 1.00 112.51 ? 164 ILE A N 1 ATOM 1046 C CA . ILE A 1 137 ? -47.149 -22.556 -32.735 1.00 107.90 ? 164 ILE A CA 1 ATOM 1047 C C . ILE A 1 137 ? -47.217 -22.307 -31.224 1.00 103.04 ? 164 ILE A C 1 ATOM 1048 O O . ILE A 1 137 ? -46.475 -21.485 -30.685 1.00 101.90 ? 164 ILE A O 1 ATOM 1049 C CB . ILE A 1 137 ? -45.869 -23.394 -33.018 1.00 101.57 ? 164 ILE A CB 1 ATOM 1050 C CG1 . ILE A 1 137 ? -44.615 -22.516 -32.896 1.00 97.49 ? 164 ILE A CG1 1 ATOM 1051 C CG2 . ILE A 1 137 ? -45.950 -24.054 -34.390 1.00 94.98 ? 164 ILE A CG2 1 ATOM 1052 C CD1 . ILE A 1 137 ? -43.330 -23.178 -33.343 1.00 102.72 ? 164 ILE A CD1 1 ATOM 1053 N N . THR A 1 138 ? -48.119 -23.007 -30.541 1.00 98.21 ? 165 THR A N 1 ATOM 1054 C CA . THR A 1 138 ? -48.258 -22.830 -29.100 1.00 97.12 ? 165 THR A CA 1 ATOM 1055 C C . THR A 1 138 ? -48.352 -24.205 -28.440 1.00 103.11 ? 165 THR A C 1 ATOM 1056 O O . THR A 1 138 ? -48.492 -25.217 -29.131 1.00 102.04 ? 165 THR A O 1 ATOM 1057 C CB . THR A 1 138 ? -49.502 -21.976 -28.745 1.00 99.31 ? 165 THR A CB 1 ATOM 1058 O OG1 . THR A 1 138 ? -50.594 -22.328 -29.605 1.00 96.39 ? 165 THR A OG1 1 ATOM 1059 C CG2 . THR A 1 138 ? -49.207 -20.495 -28.926 1.00 103.39 ? 165 THR A CG2 1 ATOM 1060 N N . TRP A 1 139 ? -48.271 -24.252 -27.113 1.00 111.63 ? 166 TRP A N 1 ATOM 1061 C CA . TRP A 1 139 ? -48.239 -25.540 -26.415 1.00 116.92 ? 166 TRP A CA 1 ATOM 1062 C C . TRP A 1 139 ? -49.216 -25.653 -25.247 1.00 118.43 ? 166 TRP A C 1 ATOM 1063 O O . TRP A 1 139 ? -49.546 -24.666 -24.584 1.00 119.17 ? 166 TRP A O 1 ATOM 1064 C CB . TRP A 1 139 ? -46.817 -25.870 -25.968 1.00 108.21 ? 166 TRP A CB 1 ATOM 1065 C CG . TRP A 1 139 ? -45.926 -26.089 -27.141 1.00 102.93 ? 166 TRP A CG 1 ATOM 1066 C CD1 . TRP A 1 139 ? -45.261 -25.145 -27.872 1.00 106.17 ? 166 TRP A CD1 1 ATOM 1067 C CD2 . TRP A 1 139 ? -45.651 -27.348 -27.760 1.00 103.14 ? 166 TRP A CD2 1 ATOM 1068 N NE1 . TRP A 1 139 ? -44.566 -25.748 -28.894 1.00 113.62 ? 166 TRP A NE1 1 ATOM 1069 C CE2 . TRP A 1 139 ? -44.790 -27.100 -28.848 1.00 109.39 ? 166 TRP A CE2 1 ATOM 1070 C CE3 . TRP A 1 139 ? -46.040 -28.666 -27.490 1.00 104.80 ? 166 TRP A CE3 1 ATOM 1071 C CZ2 . TRP A 1 139 ? -44.309 -28.122 -29.668 1.00 112.40 ? 166 TRP A CZ2 1 ATOM 1072 C CZ3 . TRP A 1 139 ? -45.561 -29.680 -28.301 1.00 105.40 ? 166 TRP A CZ3 1 ATOM 1073 C CH2 . TRP A 1 139 ? -44.706 -29.401 -29.379 1.00 107.55 ? 166 TRP A CH2 1 ATOM 1074 N N . PHE A 1 140 ? -49.691 -26.874 -25.026 1.00 108.31 ? 167 PHE A N 1 ATOM 1075 C CA . PHE A 1 140 ? -50.530 -27.194 -23.881 1.00 101.62 ? 167 PHE A CA 1 ATOM 1076 C C . PHE A 1 140 ? -50.001 -28.397 -23.093 1.00 99.70 ? 167 PHE A C 1 ATOM 1077 O O . PHE A 1 140 ? -49.615 -29.401 -23.691 1.00 97.71 ? 167 PHE A O 1 ATOM 1078 C CB . PHE A 1 140 ? -51.960 -27.436 -24.360 1.00 106.67 ? 167 PHE A CB 1 ATOM 1079 C CG . PHE A 1 140 ? -52.755 -26.171 -24.520 1.00 107.67 ? 167 PHE A CG 1 ATOM 1080 C CD1 . PHE A 1 140 ? -52.696 -25.444 -25.701 1.00 106.34 ? 167 PHE A CD1 1 ATOM 1081 C CD2 . PHE A 1 140 ? -53.526 -25.685 -23.483 1.00 113.19 ? 167 PHE A CD2 1 ATOM 1082 C CE1 . PHE A 1 140 ? -53.416 -24.270 -25.847 1.00 107.78 ? 167 PHE A CE1 1 ATOM 1083 C CE2 . PHE A 1 140 ? -54.246 -24.517 -23.622 1.00 117.30 ? 167 PHE A CE2 1 ATOM 1084 C CZ . PHE A 1 140 ? -54.192 -23.806 -24.805 1.00 116.28 ? 167 PHE A CZ 1 ATOM 1085 N N . LYS A 1 141 ? -49.972 -28.302 -21.765 1.00 99.86 ? 168 LYS A N 1 ATOM 1086 C CA . LYS A 1 141 ? -49.595 -29.458 -20.949 1.00 94.46 ? 168 LYS A CA 1 ATOM 1087 C C . LYS A 1 141 ? -50.754 -29.765 -20.017 1.00 93.82 ? 168 LYS A C 1 ATOM 1088 O O . LYS A 1 141 ? -51.292 -28.869 -19.361 1.00 99.62 ? 168 LYS A O 1 ATOM 1089 C CB . LYS A 1 141 ? -48.315 -29.234 -20.137 1.00 96.46 ? 168 LYS A CB 1 ATOM 1090 C CG . LYS A 1 141 ? -48.464 -29.674 -18.682 1.00 100.70 ? 168 LYS A CG 1 ATOM 1091 C CD . LYS A 1 141 ? -47.601 -30.893 -18.416 1.00 99.18 ? 168 LYS A CD 1 ATOM 1092 C CE . LYS A 1 141 ? -47.625 -31.326 -16.964 1.00 98.85 ? 168 LYS A CE 1 ATOM 1093 N NZ . LYS A 1 141 ? -47.098 -30.355 -15.984 1.00 108.95 ? 168 LYS A NZ 1 ATOM 1094 N N . ASP A 1 142 ? -51.122 -31.043 -19.969 1.00 93.70 ? 169 ASP A N 1 ATOM 1095 C CA . ASP A 1 142 ? -52.289 -31.503 -19.228 1.00 102.92 ? 169 ASP A CA 1 ATOM 1096 C C . ASP A 1 142 ? -53.488 -30.577 -19.421 1.00 103.65 ? 169 ASP A C 1 ATOM 1097 O O . ASP A 1 142 ? -54.170 -30.254 -18.448 1.00 119.51 ? 169 ASP A O 1 ATOM 1098 C CB . ASP A 1 142 ? -51.992 -31.636 -17.729 1.00 113.14 ? 169 ASP A CB 1 ATOM 1099 C CG . ASP A 1 142 ? -50.982 -32.729 -17.407 1.00 105.09 ? 169 ASP A CG 1 ATOM 1100 O OD1 . ASP A 1 142 ? -50.885 -33.706 -18.174 1.00 108.98 ? 169 ASP A OD1 1 ATOM 1101 O OD2 . ASP A 1 142 ? -50.328 -32.633 -16.347 1.00 99.36 ? 169 ASP A OD2 1 ATOM 1102 N N . PHE A 1 143 ? -53.677 -30.110 -20.661 1.00 94.49 ? 170 PHE A N 1 ATOM 1103 C CA . PHE A 1 143 ? -54.825 -29.290 -21.072 1.00 101.60 ? 170 PHE A CA 1 ATOM 1104 C C . PHE A 1 143 ? -54.598 -27.801 -20.770 1.00 113.79 ? 170 PHE A C 1 ATOM 1105 O O . PHE A 1 143 ? -55.275 -26.936 -21.326 1.00 119.05 ? 170 PHE A O 1 ATOM 1106 C CB . PHE A 1 143 ? -56.122 -29.791 -20.423 1.00 97.75 ? 170 PHE A CB 1 ATOM 1107 C CG . PHE A 1 143 ? -56.608 -31.102 -20.980 1.00 94.14 ? 170 PHE A CG 1 ATOM 1108 C CD1 . PHE A 1 143 ? -55.906 -31.742 -21.988 1.00 95.44 ? 170 PHE A CD1 1 ATOM 1109 C CD2 . PHE A 1 143 ? -57.735 -31.718 -20.463 1.00 101.53 ? 170 PHE A CD2 1 ATOM 1110 C CE1 . PHE A 1 143 ? -56.333 -32.953 -22.484 1.00 107.65 ? 170 PHE A CE1 1 ATOM 1111 C CE2 . PHE A 1 143 ? -58.167 -32.930 -20.958 1.00 100.29 ? 170 PHE A CE2 1 ATOM 1112 C CZ . PHE A 1 143 ? -57.465 -33.549 -21.971 1.00 105.94 ? 170 PHE A CZ 1 ATOM 1113 N N . LEU A 1 144 ? -53.665 -27.511 -19.867 1.00 113.92 ? 171 LEU A N 1 ATOM 1114 C CA . LEU A 1 144 ? -53.285 -26.129 -19.562 1.00 111.29 ? 171 LEU A CA 1 ATOM 1115 C C . LEU A 1 144 ? -52.184 -25.511 -20.433 1.00 111.23 ? 171 LEU A C 1 ATOM 1116 O O . LEU A 1 144 ? -51.267 -26.199 -20.877 1.00 112.03 ? 171 LEU A O 1 ATOM 1117 C CB . LEU A 1 144 ? -52.838 -26.054 -18.100 1.00 112.94 ? 171 LEU A CB 1 ATOM 1118 C CG . LEU A 1 144 ? -53.823 -26.663 -17.103 1.00 117.12 ? 171 LEU A CG 1 ATOM 1119 C CD1 . LEU A 1 144 ? -53.169 -26.846 -15.754 1.00 120.78 ? 171 LEU A CD1 1 ATOM 1120 C CD2 . LEU A 1 144 ? -55.054 -25.789 -16.989 1.00 126.06 ? 171 LEU A CD2 1 ATOM 1121 N N . PRO A 1 145 ? -52.279 -24.186 -20.656 1.00 111.72 ? 172 PRO A N 1 ATOM 1122 C CA . PRO A 1 145 ? -51.370 -23.341 -21.447 1.00 113.97 ? 172 PRO A CA 1 ATOM 1123 C C . PRO A 1 145 ? -50.032 -23.128 -20.737 1.00 118.73 ? 172 PRO A C 1 ATOM 1124 O O . PRO A 1 145 ? -50.026 -22.864 -19.533 1.00 122.49 ? 172 PRO A O 1 ATOM 1125 C CB . PRO A 1 145 ? -52.137 -22.019 -21.581 1.00 114.19 ? 172 PRO A CB 1 ATOM 1126 C CG . PRO A 1 145 ? -53.126 -22.028 -20.474 1.00 115.00 ? 172 PRO A CG 1 ATOM 1127 C CD . PRO A 1 145 ? -53.499 -23.454 -20.265 1.00 114.53 ? 172 PRO A CD 1 ATOM 1128 N N . VAL A 1 146 ? -48.921 -23.247 -21.462 1.00 117.67 ? 173 VAL A N 1 ATOM 1129 C CA . VAL A 1 146 ? -47.598 -23.078 -20.859 1.00 121.97 ? 173 VAL A CA 1 ATOM 1130 C C . VAL A 1 146 ? -47.218 -21.595 -20.718 1.00 136.69 ? 173 VAL A C 1 ATOM 1131 O O . VAL A 1 146 ? -47.160 -21.096 -19.593 1.00 141.32 ? 173 VAL A O 1 ATOM 1132 C CB . VAL A 1 146 ? -46.510 -23.849 -21.671 1.00 112.22 ? 173 VAL A CB 1 ATOM 1133 C CG1 . VAL A 1 146 ? -46.733 -23.712 -23.169 1.00 103.64 ? 173 VAL A CG1 1 ATOM 1134 C CG2 . VAL A 1 146 ? -45.098 -23.418 -21.269 1.00 121.74 ? 173 VAL A CG2 1 ATOM 1135 N N . ASP A 1 147 ? -46.986 -20.900 -21.834 1.00 143.05 ? 174 ASP A N 1 ATOM 1136 C CA . ASP A 1 147 ? -46.528 -19.502 -21.835 1.00 147.33 ? 174 ASP A CA 1 ATOM 1137 C C . ASP A 1 147 ? -45.231 -19.267 -21.041 1.00 139.01 ? 174 ASP A C 1 ATOM 1138 O O . ASP A 1 147 ? -45.218 -19.326 -19.810 1.00 129.98 ? 174 ASP A O 1 ATOM 1139 C CB . ASP A 1 147 ? -47.641 -18.585 -21.311 1.00 152.87 ? 174 ASP A CB 1 ATOM 1140 C CG . ASP A 1 147 ? -48.830 -18.509 -22.259 1.00 154.34 ? 174 ASP A CG 1 ATOM 1141 O OD1 . ASP A 1 147 ? -48.896 -17.549 -23.056 1.00 158.19 ? 174 ASP A OD1 1 ATOM 1142 O OD2 . ASP A 1 147 ? -49.696 -19.409 -22.213 1.00 145.07 ? 174 ASP A OD2 1 ATOM 1143 N N . THR A 1 148 ? -44.149 -18.962 -21.757 1.00 141.57 ? 175 THR A N 1 ATOM 1144 C CA . THR A 1 148 ? -42.873 -18.638 -21.120 1.00 150.59 ? 175 THR A CA 1 ATOM 1145 C C . THR A 1 148 ? -42.440 -17.189 -21.362 1.00 159.28 ? 175 THR A C 1 ATOM 1146 O O . THR A 1 148 ? -41.627 -16.897 -22.238 1.00 154.53 ? 175 THR A O 1 ATOM 1147 C CB . THR A 1 148 ? -41.756 -19.582 -21.612 1.00 142.61 ? 175 THR A CB 1 ATOM 1148 O OG1 . THR A 1 148 ? -41.379 -19.239 -22.951 1.00 143.00 ? 175 THR A OG1 1 ATOM 1149 C CG2 . THR A 1 148 ? -42.230 -21.023 -21.570 1.00 130.56 ? 175 THR A CG2 1 ATOM 1150 N N . SER A 1 149 ? -43.010 -16.297 -20.558 1.00 168.38 ? 176 SER A N 1 ATOM 1151 C CA . SER A 1 149 ? -42.897 -14.845 -20.703 1.00 171.86 ? 176 SER A CA 1 ATOM 1152 C C . SER A 1 149 ? -41.477 -14.272 -20.783 1.00 175.49 ? 176 SER A C 1 ATOM 1153 O O . SER A 1 149 ? -41.167 -13.487 -21.681 1.00 174.59 ? 176 SER A O 1 ATOM 1154 C CB . SER A 1 149 ? -43.630 -14.157 -19.546 1.00 169.51 ? 176 SER A CB 1 ATOM 1155 O OG . SER A 1 149 ? -44.544 -15.040 -18.918 1.00 171.24 ? 176 SER A OG 1 ATOM 1156 N N . ASN A 1 150 ? -40.621 -14.674 -19.846 1.00 179.68 ? 177 ASN A N 1 ATOM 1157 C CA . ASN A 1 150 ? -39.215 -14.262 -19.833 1.00 178.12 ? 177 ASN A CA 1 ATOM 1158 C C . ASN A 1 150 ? -38.247 -14.883 -20.843 1.00 176.98 ? 177 ASN A C 1 ATOM 1159 O O . ASN A 1 150 ? -37.057 -14.565 -20.819 1.00 175.32 ? 177 ASN A O 1 ATOM 1160 C CB . ASN A 1 150 ? -38.646 -14.510 -18.429 1.00 171.32 ? 177 ASN A CB 1 ATOM 1161 C CG . ASN A 1 150 ? -38.844 -15.946 -17.957 1.00 164.18 ? 177 ASN A CG 1 ATOM 1162 O OD1 . ASN A 1 150 ? -39.702 -16.669 -18.466 1.00 164.44 ? 177 ASN A OD1 1 ATOM 1163 N ND2 . ASN A 1 150 ? -38.043 -16.364 -16.981 1.00 149.92 ? 177 ASN A ND2 1 ATOM 1164 N N . ASN A 1 151 ? -38.742 -15.740 -21.736 1.00 173.29 ? 178 ASN A N 1 ATOM 1165 C CA . ASN A 1 151 ? -37.921 -16.446 -22.742 1.00 165.13 ? 178 ASN A CA 1 ATOM 1166 C C . ASN A 1 151 ? -36.524 -16.945 -22.309 1.00 158.79 ? 178 ASN A C 1 ATOM 1167 O O . ASN A 1 151 ? -35.794 -17.521 -23.117 1.00 145.76 ? 178 ASN A O 1 ATOM 1168 C CB . ASN A 1 151 ? -37.743 -15.566 -23.995 1.00 161.17 ? 178 ASN A CB 1 ATOM 1169 C CG . ASN A 1 151 ? -38.222 -14.136 -23.797 1.00 165.00 ? 178 ASN A CG 1 ATOM 1170 O OD1 . ASN A 1 151 ? -39.388 -13.819 -24.037 1.00 159.76 ? 178 ASN A OD1 1 ATOM 1171 N ND2 . ASN A 1 151 ? -37.318 -13.263 -23.364 1.00 166.98 ? 178 ASN A ND2 1 ATOM 1172 N N . ASN A 1 152 ? -36.162 -16.729 -21.046 1.00 163.40 ? 179 ASN A N 1 ATOM 1173 C CA . ASN A 1 152 ? -34.879 -17.166 -20.505 1.00 155.07 ? 179 ASN A CA 1 ATOM 1174 C C . ASN A 1 152 ? -35.019 -17.685 -19.076 1.00 150.06 ? 179 ASN A C 1 ATOM 1175 O O . ASN A 1 152 ? -35.474 -16.970 -18.182 1.00 150.71 ? 179 ASN A O 1 ATOM 1176 C CB . ASN A 1 152 ? -33.867 -16.016 -20.546 1.00 155.23 ? 179 ASN A CB 1 ATOM 1177 C CG . ASN A 1 152 ? -32.442 -16.463 -20.242 1.00 159.46 ? 179 ASN A CG 1 ATOM 1178 O OD1 . ASN A 1 152 ? -32.210 -17.536 -19.685 1.00 157.71 ? 179 ASN A OD1 1 ATOM 1179 N ND2 . ASN A 1 152 ? -31.477 -15.624 -20.605 1.00 160.37 ? 179 ASN A ND2 1 ATOM 1180 N N . GLY A 1 153 ? -34.613 -18.932 -18.870 1.00 137.47 ? 180 GLY A N 1 ATOM 1181 C CA . GLY A 1 153 ? -35.159 -19.763 -17.815 1.00 129.11 ? 180 GLY A CA 1 ATOM 1182 C C . GLY A 1 153 ? -34.948 -21.228 -18.128 1.00 116.93 ? 180 GLY A C 1 ATOM 1183 O O . GLY A 1 153 ? -34.369 -21.569 -19.160 1.00 109.33 ? 180 GLY A O 1 ATOM 1184 N N . ARG A 1 154 ? -35.399 -22.094 -17.228 1.00 121.14 ? 181 ARG A N 1 ATOM 1185 C CA . ARG A 1 154 ? -35.360 -23.533 -17.464 1.00 120.39 ? 181 ARG A CA 1 ATOM 1186 C C . ARG A 1 154 ? -36.128 -23.911 -18.740 1.00 120.48 ? 181 ARG A C 1 ATOM 1187 O O . ARG A 1 154 ? -35.709 -24.806 -19.472 1.00 120.60 ? 181 ARG A O 1 ATOM 1188 C CB . ARG A 1 154 ? -35.857 -24.280 -16.214 1.00 117.67 ? 181 ARG A CB 1 ATOM 1189 C CG . ARG A 1 154 ? -36.765 -25.480 -16.416 1.00 112.08 ? 181 ARG A CG 1 ATOM 1190 C CD . ARG A 1 154 ? -37.417 -25.838 -15.083 1.00 104.83 ? 181 ARG A CD 1 ATOM 1191 N NE . ARG A 1 154 ? -38.760 -26.396 -15.211 1.00 103.09 ? 181 ARG A NE 1 ATOM 1192 C CZ . ARG A 1 154 ? -39.871 -25.740 -14.891 1.00 109.65 ? 181 ARG A CZ 1 ATOM 1193 N NH1 . ARG A 1 154 ? -39.796 -24.501 -14.428 1.00 110.19 ? 181 ARG A NH1 1 ATOM 1194 N NH2 . ARG A 1 154 ? -41.053 -26.324 -15.029 1.00 107.30 ? 181 ARG A NH2 1 ATOM 1195 N N . ILE A 1 155 ? -37.241 -23.230 -19.011 1.00 119.89 ? 182 ILE A N 1 ATOM 1196 C CA . ILE A 1 155 ? -38.144 -23.647 -20.085 1.00 115.95 ? 182 ILE A CA 1 ATOM 1197 C C . ILE A 1 155 ? -38.168 -22.574 -21.188 1.00 124.04 ? 182 ILE A C 1 ATOM 1198 O O . ILE A 1 155 ? -38.612 -21.448 -20.951 1.00 121.40 ? 182 ILE A O 1 ATOM 1199 C CB . ILE A 1 155 ? -39.574 -23.913 -19.568 1.00 106.10 ? 182 ILE A CB 1 ATOM 1200 C CG1 . ILE A 1 155 ? -39.626 -25.221 -18.776 1.00 110.04 ? 182 ILE A CG1 1 ATOM 1201 C CG2 . ILE A 1 155 ? -40.565 -23.960 -20.719 1.00 102.79 ? 182 ILE A CG2 1 ATOM 1202 C CD1 . ILE A 1 155 ? -40.991 -25.527 -18.190 1.00 111.16 ? 182 ILE A CD1 1 ATOM 1203 N N . LYS A 1 156 ? -37.667 -22.918 -22.377 1.00 130.69 ? 183 LYS A N 1 ATOM 1204 C CA . LYS A 1 156 ? -37.580 -21.976 -23.506 1.00 128.34 ? 183 LYS A CA 1 ATOM 1205 C C . LYS A 1 156 ? -38.141 -22.528 -24.836 1.00 114.58 ? 183 LYS A C 1 ATOM 1206 O O . LYS A 1 156 ? -38.184 -23.740 -25.051 1.00 111.22 ? 183 LYS A O 1 ATOM 1207 C CB . LYS A 1 156 ? -36.124 -21.511 -23.678 1.00 132.56 ? 183 LYS A CB 1 ATOM 1208 C CG . LYS A 1 156 ? -35.455 -21.163 -22.345 1.00 134.99 ? 183 LYS A CG 1 ATOM 1209 C CD . LYS A 1 156 ? -33.991 -20.790 -22.470 1.00 134.57 ? 183 LYS A CD 1 ATOM 1210 C CE . LYS A 1 156 ? -33.176 -21.910 -23.078 1.00 121.58 ? 183 LYS A CE 1 ATOM 1211 N NZ . LYS A 1 156 ? -31.869 -21.405 -23.575 1.00 124.08 ? 183 LYS A NZ 1 ATOM 1212 N N . GLN A 1 157 ? -38.580 -21.617 -25.710 1.00 106.06 ? 184 GLN A N 1 ATOM 1213 C CA . GLN A 1 157 ? -39.131 -21.925 -27.045 1.00 101.40 ? 184 GLN A CA 1 ATOM 1214 C C . GLN A 1 157 ? -38.187 -21.724 -28.252 1.00 108.44 ? 184 GLN A C 1 ATOM 1215 O O . GLN A 1 157 ? -37.671 -20.629 -28.480 1.00 111.09 ? 184 GLN A O 1 ATOM 1216 C CB . GLN A 1 157 ? -40.401 -21.089 -27.261 1.00 99.76 ? 184 GLN A CB 1 ATOM 1217 C CG . GLN A 1 157 ? -40.895 -21.036 -28.704 1.00 110.77 ? 184 GLN A CG 1 ATOM 1218 C CD . GLN A 1 157 ? -41.654 -22.283 -29.135 1.00 113.71 ? 184 GLN A CD 1 ATOM 1219 O OE1 . GLN A 1 157 ? -42.814 -22.478 -28.770 1.00 110.61 ? 184 GLN A OE1 1 ATOM 1220 N NE2 . GLN A 1 157 ? -41.003 -23.124 -29.932 1.00 115.47 ? 184 GLN A NE2 1 ATOM 1221 N N . LEU A 1 158 ? -37.970 -22.800 -29.008 1.00 113.61 ? 185 LEU A N 1 ATOM 1222 C CA . LEU A 1 158 ? -37.250 -22.778 -30.294 1.00 110.72 ? 185 LEU A CA 1 ATOM 1223 C C . LEU A 1 158 ? -38.122 -22.544 -31.540 1.00 121.38 ? 185 LEU A C 1 ATOM 1224 O O . LEU A 1 158 ? -39.246 -23.036 -31.633 1.00 123.94 ? 185 LEU A O 1 ATOM 1225 C CB . LEU A 1 158 ? -36.449 -24.069 -30.499 1.00 106.78 ? 185 LEU A CB 1 ATOM 1226 C CG . LEU A 1 158 ? -35.483 -24.522 -29.407 1.00 115.92 ? 185 LEU A CG 1 ATOM 1227 C CD1 . LEU A 1 158 ? -35.231 -26.016 -29.499 1.00 112.77 ? 185 LEU A CD1 1 ATOM 1228 C CD2 . LEU A 1 158 ? -34.179 -23.760 -29.530 1.00 121.01 ? 185 LEU A CD2 1 ATOM 1229 N N . ARG A 1 159 ? -37.566 -21.804 -32.498 1.00 129.10 ? 186 ARG A N 1 ATOM 1230 C CA . ARG A 1 159 ? -38.220 -21.509 -33.770 1.00 133.70 ? 186 ARG A CA 1 ATOM 1231 C C . ARG A 1 159 ? -37.422 -21.734 -35.054 1.00 131.32 ? 186 ARG A C 1 ATOM 1232 O O . ARG A 1 159 ? -36.264 -21.342 -35.177 1.00 139.62 ? 186 ARG A O 1 ATOM 1233 C CB . ARG A 1 159 ? -38.604 -20.022 -33.735 1.00 138.74 ? 186 ARG A CB 1 ATOM 1234 C CG . ARG A 1 159 ? -39.116 -19.400 -35.026 1.00 145.53 ? 186 ARG A CG 1 ATOM 1235 C CD . ARG A 1 159 ? -40.453 -19.808 -35.575 1.00 145.37 ? 186 ARG A CD 1 ATOM 1236 N NE . ARG A 1 159 ? -41.157 -18.589 -35.971 1.00 159.12 ? 186 ARG A NE 1 ATOM 1237 C CZ . ARG A 1 159 ? -40.907 -17.905 -37.088 1.00 163.11 ? 186 ARG A CZ 1 ATOM 1238 N NH1 . ARG A 1 159 ? -39.949 -18.298 -37.919 1.00 155.44 ? 186 ARG A NH1 1 ATOM 1239 N NH2 . ARG A 1 159 ? -41.611 -16.816 -37.372 1.00 157.62 ? 186 ARG A NH2 1 ATOM 1240 N N . SER A 1 160 ? -38.079 -22.412 -35.992 1.00 124.47 ? 187 SER A N 1 ATOM 1241 C CA . SER A 1 160 ? -37.567 -22.709 -37.328 1.00 131.00 ? 187 SER A CA 1 ATOM 1242 C C . SER A 1 160 ? -37.241 -21.476 -38.144 1.00 140.02 ? 187 SER A C 1 ATOM 1243 O O . SER A 1 160 ? -37.820 -20.416 -37.910 1.00 143.34 ? 187 SER A O 1 ATOM 1244 C CB . SER A 1 160 ? -38.576 -23.539 -38.108 1.00 136.50 ? 187 SER A CB 1 ATOM 1245 O OG . SER A 1 160 ? -37.970 -24.156 -39.228 1.00 143.54 ? 187 SER A OG 1 ATOM 1246 N N . GLU A 1 161 ? -36.336 -21.594 -39.109 1.00 138.57 ? 188 GLU A N 1 ATOM 1247 C CA . GLU A 1 161 ? -36.187 -20.476 -40.021 1.00 142.23 ? 188 GLU A CA 1 ATOM 1248 C C . GLU A 1 161 ? -36.921 -20.716 -41.336 1.00 145.30 ? 188 GLU A C 1 ATOM 1249 O O . GLU A 1 161 ? -36.656 -21.688 -42.044 1.00 142.22 ? 188 GLU A O 1 ATOM 1250 C CB . GLU A 1 161 ? -34.718 -20.190 -40.313 1.00 146.13 ? 188 GLU A CB 1 ATOM 1251 C CG . GLU A 1 161 ? -34.410 -18.710 -40.362 1.00 153.82 ? 188 GLU A CG 1 ATOM 1252 C CD . GLU A 1 161 ? -33.027 -18.382 -39.859 1.00 162.10 ? 188 GLU A CD 1 ATOM 1253 O OE1 . GLU A 1 161 ? -32.068 -19.075 -40.262 1.00 160.65 ? 188 GLU A OE1 1 ATOM 1254 O OE2 . GLU A 1 161 ? -32.896 -17.425 -39.067 1.00 173.90 ? 188 GLU A OE2 1 ATOM 1255 N N . SER A 1 162 ? -37.857 -19.827 -41.640 1.00 146.46 ? 189 SER A N 1 ATOM 1256 C CA . SER A 1 162 ? -38.829 -20.064 -42.694 1.00 144.90 ? 189 SER A CA 1 ATOM 1257 C C . SER A 1 162 ? -38.029 -19.862 -43.980 1.00 150.85 ? 189 SER A C 1 ATOM 1258 O O . SER A 1 162 ? -37.948 -18.734 -44.466 1.00 153.75 ? 189 SER A O 1 ATOM 1259 C CB . SER A 1 162 ? -40.034 -19.129 -42.589 1.00 124.21 ? 189 SER A CB 1 ATOM 1260 O OG . SER A 1 162 ? -40.962 -19.380 -43.630 1.00 116.57 ? 189 SER A OG 1 ATOM 1261 N N . ILE A 1 163 ? -37.422 -20.903 -44.542 1.00 140.72 ? 190 ILE A N 1 ATOM 1262 C CA . ILE A 1 163 ? -37.169 -20.846 -45.976 1.00 130.78 ? 190 ILE A CA 1 ATOM 1263 C C . ILE A 1 163 ? -38.460 -20.974 -46.773 1.00 131.33 ? 190 ILE A C 1 ATOM 1264 O O . ILE A 1 163 ? -39.395 -21.672 -46.377 1.00 134.34 ? 190 ILE A O 1 ATOM 1265 C CB . ILE A 1 163 ? -36.152 -21.937 -46.420 1.00 127.02 ? 190 ILE A CB 1 ATOM 1266 C CG1 . ILE A 1 163 ? -36.728 -23.347 -46.262 1.00 129.44 ? 190 ILE A CG1 1 ATOM 1267 C CG2 . ILE A 1 163 ? -34.847 -21.798 -45.647 1.00 125.95 ? 190 ILE A CG2 1 ATOM 1268 C CD1 . ILE A 1 163 ? -37.122 -24.002 -47.574 1.00 133.79 ? 190 ILE A CD1 1 ATOM 1269 N N . GLY A 1 164 ? -38.489 -20.267 -47.898 1.00 123.09 ? 191 GLY A N 1 ATOM 1270 C CA . GLY A 1 164 ? -39.681 -20.104 -48.708 1.00 128.22 ? 191 GLY A CA 1 ATOM 1271 C C . GLY A 1 164 ? -40.112 -21.341 -49.466 1.00 134.19 ? 191 GLY A C 1 ATOM 1272 O O . GLY A 1 164 ? -39.744 -21.499 -50.630 1.00 134.63 ? 191 GLY A O 1 ATOM 1273 N N . GLY A 1 165 ? -40.869 -22.228 -48.829 1.00 133.06 ? 192 GLY A N 1 ATOM 1274 C CA . GLY A 1 165 ? -41.023 -23.559 -49.382 1.00 128.69 ? 192 GLY A CA 1 ATOM 1275 C C . GLY A 1 165 ? -41.312 -24.722 -48.455 1.00 121.43 ? 192 GLY A C 1 ATOM 1276 O O . GLY A 1 165 ? -42.000 -25.658 -48.857 1.00 119.80 ? 192 GLY A O 1 ATOM 1277 N N . THR A 1 166 ? -40.810 -24.691 -47.224 1.00 120.15 ? 193 THR A N 1 ATOM 1278 C CA . THR A 1 166 ? -40.950 -25.871 -46.380 1.00 126.50 ? 193 THR A CA 1 ATOM 1279 C C . THR A 1 166 ? -42.041 -25.678 -45.315 1.00 132.51 ? 193 THR A C 1 ATOM 1280 O O . THR A 1 166 ? -42.509 -24.556 -45.113 1.00 130.65 ? 193 THR A O 1 ATOM 1281 C CB . THR A 1 166 ? -39.561 -26.164 -45.705 1.00 130.57 ? 193 THR A CB 1 ATOM 1282 O OG1 . THR A 1 166 ? -39.450 -27.536 -45.305 1.00 131.65 ? 193 THR A OG1 1 ATOM 1283 C CG2 . THR A 1 166 ? -39.314 -25.238 -44.512 1.00 126.43 ? 193 THR A CG2 1 ATOM 1284 N N . PRO A 1 167 ? -42.459 -26.770 -44.633 1.00 133.18 ? 194 PRO A N 1 ATOM 1285 C CA . PRO A 1 167 ? -43.302 -26.676 -43.433 1.00 127.89 ? 194 PRO A CA 1 ATOM 1286 C C . PRO A 1 167 ? -42.619 -25.900 -42.309 1.00 127.72 ? 194 PRO A C 1 ATOM 1287 O O . PRO A 1 167 ? -41.393 -25.947 -42.210 1.00 127.14 ? 194 PRO A O 1 ATOM 1288 C CB . PRO A 1 167 ? -43.550 -28.148 -43.060 1.00 115.28 ? 194 PRO A CB 1 ATOM 1289 C CG . PRO A 1 167 ? -42.451 -28.899 -43.727 1.00 111.19 ? 194 PRO A CG 1 ATOM 1290 C CD . PRO A 1 167 ? -42.307 -28.179 -45.037 1.00 124.83 ? 194 PRO A CD 1 ATOM 1291 N N . ILE A 1 168 ? -43.379 -25.213 -41.463 1.00 121.39 ? 195 ILE A N 1 ATOM 1292 C CA . ILE A 1 168 ? -42.757 -24.615 -40.294 1.00 113.23 ? 195 ILE A CA 1 ATOM 1293 C C . ILE A 1 168 ? -42.397 -25.665 -39.245 1.00 109.45 ? 195 ILE A C 1 ATOM 1294 O O . ILE A 1 168 ? -43.203 -26.525 -38.892 1.00 109.19 ? 195 ILE A O 1 ATOM 1295 C CB . ILE A 1 168 ? -43.666 -23.538 -39.644 1.00 113.97 ? 195 ILE A CB 1 ATOM 1296 C CG1 . ILE A 1 168 ? -43.902 -22.377 -40.612 1.00 123.89 ? 195 ILE A CG1 1 ATOM 1297 C CG2 . ILE A 1 168 ? -43.036 -22.992 -38.373 1.00 109.18 ? 195 ILE A CG2 1 ATOM 1298 C CD1 . ILE A 1 168 ? -44.375 -21.100 -39.932 1.00 122.52 ? 195 ILE A CD1 1 ATOM 1299 N N . ARG A 1 169 ? -41.161 -25.583 -38.770 1.00 110.18 ? 196 ARG A N 1 ATOM 1300 C CA . ARG A 1 169 ? -40.627 -26.473 -37.751 1.00 116.09 ? 196 ARG A CA 1 ATOM 1301 C C . ARG A 1 169 ? -40.837 -25.723 -36.448 1.00 125.13 ? 196 ARG A C 1 ATOM 1302 O O . ARG A 1 169 ? -40.970 -24.501 -36.450 1.00 128.40 ? 196 ARG A O 1 ATOM 1303 C CB . ARG A 1 169 ? -39.149 -26.806 -37.954 1.00 117.39 ? 196 ARG A CB 1 ATOM 1304 C CG . ARG A 1 169 ? -38.803 -28.227 -38.339 1.00 107.08 ? 196 ARG A CG 1 ATOM 1305 C CD . ARG A 1 169 ? -39.734 -28.871 -39.334 1.00 111.56 ? 196 ARG A CD 1 ATOM 1306 N NE . ARG A 1 169 ? -39.171 -30.160 -39.718 1.00 109.58 ? 196 ARG A NE 1 ATOM 1307 C CZ . ARG A 1 169 ? -39.331 -30.745 -40.897 1.00 103.42 ? 196 ARG A CZ 1 ATOM 1308 N NH1 . ARG A 1 169 ? -40.059 -30.172 -41.845 1.00 97.75 ? 196 ARG A NH1 1 ATOM 1309 N NH2 . ARG A 1 169 ? -38.751 -31.913 -41.121 1.00 100.44 ? 196 ARG A NH2 1 ATOM 1310 N N . GLY A 1 170 ? -40.884 -26.434 -35.335 1.00 129.69 ? 197 GLY A N 1 ATOM 1311 C CA . GLY A 1 170 ? -41.152 -25.783 -34.072 1.00 120.53 ? 197 GLY A CA 1 ATOM 1312 C C . GLY A 1 170 ? -40.860 -26.726 -32.937 1.00 118.55 ? 197 GLY A C 1 ATOM 1313 O O . GLY A 1 170 ? -41.182 -27.912 -33.006 1.00 124.43 ? 197 GLY A O 1 ATOM 1314 N N . ALA A 1 171 ? -40.270 -26.197 -31.870 1.00 107.87 ? 198 ALA A N 1 ATOM 1315 C CA . ALA A 1 171 ? -39.959 -27.049 -30.740 1.00 104.30 ? 198 ALA A CA 1 ATOM 1316 C C . ALA A 1 171 ? -40.078 -26.381 -29.380 1.00 109.05 ? 198 ALA A C 1 ATOM 1317 O O . ALA A 1 171 ? -40.137 -25.159 -29.266 1.00 112.01 ? 198 ALA A O 1 ATOM 1318 C CB . ALA A 1 171 ? -38.543 -27.592 -30.913 1.00 100.15 ? 198 ALA A CB 1 ATOM 1319 N N . LEU A 1 172 ? -40.125 -27.225 -28.352 1.00 110.31 ? 199 LEU A N 1 ATOM 1320 C CA . LEU A 1 172 ? -40.176 -26.806 -26.953 1.00 105.79 ? 199 LEU A CA 1 ATOM 1321 C C . LEU A 1 172 ? -38.971 -27.357 -26.183 1.00 108.14 ? 199 LEU A C 1 ATOM 1322 O O . LEU A 1 172 ? -38.812 -28.573 -26.071 1.00 107.90 ? 199 LEU A O 1 ATOM 1323 C CB . LEU A 1 172 ? -41.496 -27.250 -26.312 1.00 92.87 ? 199 LEU A CB 1 ATOM 1324 C CG . LEU A 1 172 ? -41.924 -26.568 -25.005 1.00 83.31 ? 199 LEU A CG 1 ATOM 1325 C CD1 . LEU A 1 172 ? -43.436 -26.574 -24.869 1.00 82.71 ? 199 LEU A CD1 1 ATOM 1326 C CD2 . LEU A 1 172 ? -41.302 -27.224 -23.794 1.00 95.25 ? 199 LEU A CD2 1 ATOM 1327 N N . GLN A 1 173 ? -38.113 -26.479 -25.676 1.00 108.05 ? 200 GLN A N 1 ATOM 1328 C CA . GLN A 1 173 ? -36.879 -26.922 -25.027 1.00 109.97 ? 200 GLN A CA 1 ATOM 1329 C C . GLN A 1 173 ? -36.915 -26.720 -23.501 1.00 113.78 ? 200 GLN A C 1 ATOM 1330 O O . GLN A 1 173 ? -37.086 -25.604 -23.015 1.00 118.27 ? 200 GLN A O 1 ATOM 1331 C CB . GLN A 1 173 ? -35.673 -26.207 -25.640 1.00 116.15 ? 200 GLN A CB 1 ATOM 1332 C CG . GLN A 1 173 ? -34.383 -27.007 -25.545 1.00 128.08 ? 200 GLN A CG 1 ATOM 1333 C CD . GLN A 1 173 ? -33.170 -26.228 -26.017 1.00 129.31 ? 200 GLN A CD 1 ATOM 1334 O OE1 . GLN A 1 173 ? -32.475 -26.643 -26.948 1.00 122.05 ? 200 GLN A OE1 1 ATOM 1335 N NE2 . GLN A 1 173 ? -32.915 -25.086 -25.383 1.00 128.40 ? 200 GLN A NE2 1 ATOM 1336 N N . ILE A 1 174 ? -36.734 -27.821 -22.768 1.00 108.00 ? 201 ILE A N 1 ATOM 1337 C CA . ILE A 1 174 ? -36.849 -27.897 -21.304 1.00 103.76 ? 201 ILE A CA 1 ATOM 1338 C C . ILE A 1 174 ? -35.516 -28.212 -20.629 1.00 106.53 ? 201 ILE A C 1 ATOM 1339 O O . ILE A 1 174 ? -35.098 -29.374 -20.602 1.00 103.96 ? 201 ILE A O 1 ATOM 1340 C CB . ILE A 1 174 ? -37.865 -28.976 -20.847 1.00 101.89 ? 201 ILE A CB 1 ATOM 1341 C CG1 . ILE A 1 174 ? -39.246 -28.723 -21.450 1.00 102.48 ? 201 ILE A CG1 1 ATOM 1342 C CG2 . ILE A 1 174 ? -37.966 -29.000 -19.326 1.00 111.48 ? 201 ILE A CG2 1 ATOM 1343 C CD1 . ILE A 1 174 ? -40.370 -29.544 -20.815 1.00 97.07 ? 201 ILE A CD1 1 ATOM 1344 N N . GLU A 1 175 ? -34.814 -27.200 -20.123 1.00 111.89 ? 202 GLU A N 1 ATOM 1345 C CA . GLU A 1 175 ? -33.540 -27.497 -19.489 1.00 114.47 ? 202 GLU A CA 1 ATOM 1346 C C . GLU A 1 175 ? -33.844 -28.108 -18.127 1.00 113.07 ? 202 GLU A C 1 ATOM 1347 O O . GLU A 1 175 ? -34.821 -27.721 -17.487 1.00 103.36 ? 202 GLU A O 1 ATOM 1348 C CB . GLU A 1 175 ? -32.739 -26.206 -19.259 1.00 116.25 ? 202 GLU A CB 1 ATOM 1349 C CG . GLU A 1 175 ? -32.455 -25.337 -20.476 1.00 110.83 ? 202 GLU A CG 1 ATOM 1350 C CD . GLU A 1 175 ? -31.621 -26.000 -21.541 1.00 116.69 ? 202 GLU A CD 1 ATOM 1351 O OE1 . GLU A 1 175 ? -31.030 -27.067 -21.275 1.00 125.70 ? 202 GLU A OE1 1 ATOM 1352 O OE2 . GLU A 1 175 ? -31.559 -25.440 -22.657 1.00 114.33 ? 202 GLU A OE2 1 ATOM 1353 N N . GLN A 1 176 ? -33.010 -29.044 -17.679 1.00 116.10 ? 203 GLN A N 1 ATOM 1354 C CA . GLN A 1 176 ? -33.134 -29.614 -16.336 1.00 108.90 ? 203 GLN A CA 1 ATOM 1355 C C . GLN A 1 176 ? -34.538 -30.166 -16.046 1.00 108.21 ? 203 GLN A C 1 ATOM 1356 O O . GLN A 1 176 ? -35.235 -29.653 -15.166 1.00 108.01 ? 203 GLN A O 1 ATOM 1357 C CB . GLN A 1 176 ? -32.695 -28.583 -15.298 1.00 106.00 ? 203 GLN A CB 1 ATOM 1358 C CG . GLN A 1 176 ? -31.203 -28.294 -15.422 1.00 103.97 ? 203 GLN A CG 1 ATOM 1359 C CD . GLN A 1 176 ? -30.686 -27.291 -14.418 1.00 106.50 ? 203 GLN A CD 1 ATOM 1360 O OE1 . GLN A 1 176 ? -31.403 -26.384 -14.000 1.00 113.41 ? 203 GLN A OE1 1 ATOM 1361 N NE2 . GLN A 1 176 ? -29.424 -27.448 -14.027 1.00 99.93 ? 203 GLN A NE2 1 ATOM 1362 N N . SER A 1 177 ? -34.957 -31.188 -16.790 1.00 108.84 ? 204 SER A N 1 ATOM 1363 C CA . SER A 1 177 ? -36.323 -31.717 -16.677 1.00 106.15 ? 204 SER A CA 1 ATOM 1364 C C . SER A 1 177 ? -36.633 -32.266 -15.283 1.00 104.09 ? 204 SER A C 1 ATOM 1365 O O . SER A 1 177 ? -35.834 -32.989 -14.702 1.00 110.71 ? 204 SER A O 1 ATOM 1366 C CB . SER A 1 177 ? -36.561 -32.812 -17.722 1.00 107.48 ? 204 SER A CB 1 ATOM 1367 O OG . SER A 1 177 ? -35.946 -32.491 -18.957 1.00 113.64 ? 204 SER A OG 1 ATOM 1368 N N . GLU A 1 178 ? -37.795 -31.896 -14.750 1.00 100.06 ? 205 GLU A N 1 ATOM 1369 C CA . GLU A 1 178 ? -38.278 -32.409 -13.466 1.00 98.89 ? 205 GLU A CA 1 ATOM 1370 C C . GLU A 1 178 ? -39.630 -33.112 -13.585 1.00 92.02 ? 205 GLU A C 1 ATOM 1371 O O . GLU A 1 178 ? -40.343 -32.948 -14.569 1.00 90.31 ? 205 GLU A O 1 ATOM 1372 C CB . GLU A 1 178 ? -38.387 -31.296 -12.417 1.00 103.79 ? 205 GLU A CB 1 ATOM 1373 C CG . GLU A 1 178 ? -39.126 -30.043 -12.864 1.00 104.70 ? 205 GLU A CG 1 ATOM 1374 C CD . GLU A 1 178 ? -38.748 -28.817 -12.048 1.00 93.01 ? 205 GLU A CD 1 ATOM 1375 O OE1 . GLU A 1 178 ? -37.626 -28.299 -12.230 1.00 95.96 ? 205 GLU A OE1 1 ATOM 1376 O OE2 . GLU A 1 178 ? -39.567 -28.383 -11.208 1.00 78.37 ? 205 GLU A OE2 1 ATOM 1377 N N . GLU A 1 179 ? -39.932 -33.950 -12.598 1.00 93.26 ? 206 GLU A N 1 ATOM 1378 C CA . GLU A 1 179 ? -41.163 -34.743 -12.550 1.00 98.44 ? 206 GLU A CA 1 ATOM 1379 C C . GLU A 1 179 ? -42.451 -33.909 -12.699 1.00 96.79 ? 206 GLU A C 1 ATOM 1380 O O . GLU A 1 179 ? -43.477 -34.413 -13.153 1.00 94.89 ? 206 GLU A O 1 ATOM 1381 C CB . GLU A 1 179 ? -41.221 -35.533 -11.241 1.00 108.57 ? 206 GLU A CB 1 ATOM 1382 C CG . GLU A 1 179 ? -42.556 -36.209 -10.993 1.00 107.89 ? 206 GLU A CG 1 ATOM 1383 C CD . GLU A 1 179 ? -42.635 -36.893 -9.650 1.00 119.11 ? 206 GLU A CD 1 ATOM 1384 O OE1 . GLU A 1 179 ? -41.575 -37.247 -9.091 1.00 123.28 ? 206 GLU A OE1 1 ATOM 1385 O OE2 . GLU A 1 179 ? -43.766 -37.059 -9.147 1.00 123.48 ? 206 GLU A OE2 1 ATOM 1386 N N . SER A 1 180 ? -42.414 -32.640 -12.303 1.00 100.39 ? 207 SER A N 1 ATOM 1387 C CA . SER A 1 180 ? -43.569 -31.767 -12.519 1.00 105.17 ? 207 SER A CA 1 ATOM 1388 C C . SER A 1 180 ? -43.867 -31.614 -14.010 1.00 97.71 ? 207 SER A C 1 ATOM 1389 O O . SER A 1 180 ? -45.003 -31.343 -14.407 1.00 96.07 ? 207 SER A O 1 ATOM 1390 C CB . SER A 1 180 ? -43.332 -30.392 -11.885 1.00 103.29 ? 207 SER A CB 1 ATOM 1391 O OG . SER A 1 180 ? -42.453 -29.606 -12.672 1.00 102.93 ? 207 SER A OG 1 ATOM 1392 N N . ASP A 1 181 ? -42.832 -31.790 -14.824 1.00 94.38 ? 208 ASP A N 1 ATOM 1393 C CA . ASP A 1 181 ? -42.928 -31.670 -16.274 1.00 86.25 ? 208 ASP A CA 1 ATOM 1394 C C . ASP A 1 181 ? -43.639 -32.888 -16.878 1.00 79.15 ? 208 ASP A C 1 ATOM 1395 O O . ASP A 1 181 ? -44.122 -32.825 -18.005 1.00 83.65 ? 208 ASP A O 1 ATOM 1396 C CB . ASP A 1 181 ? -41.540 -31.481 -16.898 1.00 87.68 ? 208 ASP A CB 1 ATOM 1397 C CG . ASP A 1 181 ? -40.919 -30.130 -16.551 1.00 89.03 ? 208 ASP A CG 1 ATOM 1398 O OD1 . ASP A 1 181 ? -41.663 -29.128 -16.502 1.00 87.53 ? 208 ASP A OD1 1 ATOM 1399 O OD2 . ASP A 1 181 ? -39.691 -30.071 -16.320 1.00 89.58 ? 208 ASP A OD2 1 ATOM 1400 N N . GLN A 1 182 ? -43.678 -33.999 -16.139 1.00 71.37 ? 209 GLN A N 1 ATOM 1401 C CA . GLN A 1 182 ? -44.448 -35.169 -16.567 1.00 68.86 ? 209 GLN A CA 1 ATOM 1402 C C . GLN A 1 182 ? -45.893 -34.820 -16.880 1.00 70.26 ? 209 GLN A C 1 ATOM 1403 O O . GLN A 1 182 ? -46.460 -33.934 -16.259 1.00 72.73 ? 209 GLN A O 1 ATOM 1404 C CB . GLN A 1 182 ? -44.468 -36.232 -15.465 1.00 78.88 ? 209 GLN A CB 1 ATOM 1405 C CG . GLN A 1 182 ? -43.134 -36.768 -15.021 1.00 80.29 ? 209 GLN A CG 1 ATOM 1406 C CD . GLN A 1 182 ? -42.741 -37.981 -15.803 1.00 84.59 ? 209 GLN A CD 1 ATOM 1407 O OE1 . GLN A 1 182 ? -42.697 -37.936 -17.024 1.00 89.82 ? 209 GLN A OE1 1 ATOM 1408 N NE2 . GLN A 1 182 ? -42.455 -39.079 -15.111 1.00 82.18 ? 209 GLN A NE2 1 ATOM 1409 N N . GLY A 1 183 ? -46.498 -35.548 -17.812 1.00 72.54 ? 210 GLY A N 1 ATOM 1410 C CA . GLY A 1 183 ? -47.861 -35.267 -18.228 1.00 81.29 ? 210 GLY A CA 1 ATOM 1411 C C . GLY A 1 183 ? -48.134 -35.436 -19.712 1.00 85.67 ? 210 GLY A C 1 ATOM 1412 O O . GLY A 1 183 ? -47.310 -35.962 -20.462 1.00 80.66 ? 210 GLY A O 1 ATOM 1413 N N . LYS A 1 184 ? -49.316 -34.986 -20.125 1.00 90.63 ? 211 LYS A N 1 ATOM 1414 C CA . LYS A 1 184 ? -49.827 -35.231 -21.471 1.00 82.11 ? 211 LYS A CA 1 ATOM 1415 C C . LYS A 1 184 ? -49.807 -33.943 -22.301 1.00 85.15 ? 211 LYS A C 1 ATOM 1416 O O . LYS A 1 184 ? -50.640 -33.060 -22.091 1.00 87.00 ? 211 LYS A O 1 ATOM 1417 C CB . LYS A 1 184 ? -51.247 -35.798 -21.396 1.00 80.64 ? 211 LYS A CB 1 ATOM 1418 C CG . LYS A 1 184 ? -51.842 -36.239 -22.721 1.00 73.90 ? 211 LYS A CG 1 ATOM 1419 C CD . LYS A 1 184 ? -53.166 -36.952 -22.503 1.00 63.97 ? 211 LYS A CD 1 ATOM 1420 C CE . LYS A 1 184 ? -53.905 -37.142 -23.814 1.00 57.99 ? 211 LYS A CE 1 ATOM 1421 N NZ . LYS A 1 184 ? -55.289 -37.644 -23.601 1.00 56.43 ? 211 LYS A NZ 1 ATOM 1422 N N . TYR A 1 185 ? -48.861 -33.834 -23.230 1.00 89.81 ? 212 TYR A N 1 ATOM 1423 C CA . TYR A 1 185 ? -48.681 -32.608 -24.011 1.00 93.58 ? 212 TYR A CA 1 ATOM 1424 C C . TYR A 1 185 ? -49.329 -32.583 -25.399 1.00 92.95 ? 212 TYR A C 1 ATOM 1425 O O . TYR A 1 185 ? -49.335 -33.585 -26.115 1.00 88.17 ? 212 TYR A O 1 ATOM 1426 C CB . TYR A 1 185 ? -47.191 -32.296 -24.197 1.00 88.27 ? 212 TYR A CB 1 ATOM 1427 C CG . TYR A 1 185 ? -46.427 -31.898 -22.951 1.00 76.41 ? 212 TYR A CG 1 ATOM 1428 C CD1 . TYR A 1 185 ? -46.145 -32.808 -21.941 1.00 79.60 ? 212 TYR A CD1 1 ATOM 1429 C CD2 . TYR A 1 185 ? -45.977 -30.593 -22.800 1.00 77.74 ? 212 TYR A CD2 1 ATOM 1430 C CE1 . TYR A 1 185 ? -45.433 -32.419 -20.809 1.00 87.20 ? 212 TYR A CE1 1 ATOM 1431 C CE2 . TYR A 1 185 ? -45.272 -30.195 -21.684 1.00 72.53 ? 212 TYR A CE2 1 ATOM 1432 C CZ . TYR A 1 185 ? -44.999 -31.109 -20.688 1.00 79.76 ? 212 TYR A CZ 1 ATOM 1433 O OH . TYR A 1 185 ? -44.293 -30.697 -19.578 1.00 81.97 ? 212 TYR A OH 1 ATOM 1434 N N . GLU A 1 186 ? -49.894 -31.436 -25.765 1.00 93.43 ? 213 GLU A N 1 ATOM 1435 C CA . GLU A 1 186 ? -50.418 -31.243 -27.114 1.00 101.03 ? 213 GLU A CA 1 ATOM 1436 C C . GLU A 1 186 ? -50.089 -29.828 -27.609 1.00 105.78 ? 213 GLU A C 1 ATOM 1437 O O . GLU A 1 186 ? -50.123 -28.864 -26.845 1.00 100.46 ? 213 GLU A O 1 ATOM 1438 C CB . GLU A 1 186 ? -51.919 -31.529 -27.163 1.00 104.09 ? 213 GLU A CB 1 ATOM 1439 C CG . GLU A 1 186 ? -52.788 -30.577 -26.389 1.00 101.43 ? 213 GLU A CG 1 ATOM 1440 C CD . GLU A 1 186 ? -54.166 -31.152 -26.151 1.00 105.66 ? 213 GLU A CD 1 ATOM 1441 O OE1 . GLU A 1 186 ? -54.781 -30.800 -25.125 1.00 113.76 ? 213 GLU A OE1 1 ATOM 1442 O OE2 . GLU A 1 186 ? -54.632 -31.962 -26.985 1.00 105.18 ? 213 GLU A OE2 1 ATOM 1443 N N . CYS A 1 187 ? -49.757 -29.731 -28.893 1.00 114.95 ? 214 CYS A N 1 ATOM 1444 C CA . CYS A 1 187 ? -49.385 -28.481 -29.557 1.00 108.28 ? 214 CYS A CA 1 ATOM 1445 C C . CYS A 1 187 ? -50.482 -27.907 -30.462 1.00 105.50 ? 214 CYS A C 1 ATOM 1446 O O . CYS A 1 187 ? -51.411 -28.619 -30.843 1.00 105.76 ? 214 CYS A O 1 ATOM 1447 C CB . CYS A 1 187 ? -48.115 -28.693 -30.372 1.00 103.40 ? 214 CYS A CB 1 ATOM 1448 S SG . CYS A 1 187 ? -48.464 -29.376 -31.982 1.00 102.71 ? 214 CYS A SG 1 ATOM 1449 N N . VAL A 1 188 ? -50.380 -26.618 -30.796 1.00 98.15 ? 215 VAL A N 1 ATOM 1450 C CA . VAL A 1 188 ? -51.491 -25.894 -31.409 1.00 97.27 ? 215 VAL A CA 1 ATOM 1451 C C . VAL A 1 188 ? -51.006 -24.928 -32.496 1.00 97.99 ? 215 VAL A C 1 ATOM 1452 O O . VAL A 1 188 ? -50.133 -24.099 -32.244 1.00 97.24 ? 215 VAL A O 1 ATOM 1453 C CB . VAL A 1 188 ? -52.264 -25.071 -30.345 1.00 99.31 ? 215 VAL A CB 1 ATOM 1454 C CG1 . VAL A 1 188 ? -53.269 -24.142 -31.002 1.00 104.71 ? 215 VAL A CG1 1 ATOM 1455 C CG2 . VAL A 1 188 ? -52.949 -25.979 -29.347 1.00 104.77 ? 215 VAL A CG2 1 ATOM 1456 N N . ALA A 1 189 ? -51.571 -25.035 -33.700 1.00 98.99 ? 216 ALA A N 1 ATOM 1457 C CA . ALA A 1 189 ? -51.143 -24.187 -34.815 1.00 97.83 ? 216 ALA A CA 1 ATOM 1458 C C . ALA A 1 189 ? -52.237 -23.199 -35.221 1.00 104.82 ? 216 ALA A C 1 ATOM 1459 O O . ALA A 1 189 ? -53.344 -23.605 -35.570 1.00 105.80 ? 216 ALA A O 1 ATOM 1460 C CB . ALA A 1 189 ? -50.737 -25.043 -36.008 1.00 94.75 ? 216 ALA A CB 1 ATOM 1461 N N . THR A 1 190 ? -51.917 -21.908 -35.178 1.00 109.97 ? 217 THR A N 1 ATOM 1462 C CA . THR A 1 190 ? -52.889 -20.845 -35.432 1.00 112.51 ? 217 THR A CA 1 ATOM 1463 C C . THR A 1 190 ? -52.418 -19.909 -36.557 1.00 114.19 ? 217 THR A C 1 ATOM 1464 O O . THR A 1 190 ? -51.218 -19.710 -36.739 1.00 112.13 ? 217 THR A O 1 ATOM 1465 C CB . THR A 1 190 ? -53.175 -20.028 -34.140 1.00 114.98 ? 217 THR A CB 1 ATOM 1466 O OG1 . THR A 1 190 ? -53.539 -20.921 -33.082 1.00 119.32 ? 217 THR A OG1 1 ATOM 1467 C CG2 . THR A 1 190 ? -54.310 -19.026 -34.348 1.00 108.76 ? 217 THR A CG2 1 ATOM 1468 N N . ASN A 1 191 ? -53.362 -19.343 -37.305 1.00 119.33 ? 218 ASN A N 1 ATOM 1469 C CA . ASN A 1 191 ? -53.098 -18.179 -38.150 1.00 123.07 ? 218 ASN A CA 1 ATOM 1470 C C . ASN A 1 191 ? -54.402 -17.427 -38.393 1.00 122.86 ? 218 ASN A C 1 ATOM 1471 O O . ASN A 1 191 ? -55.397 -17.675 -37.712 1.00 118.12 ? 218 ASN A O 1 ATOM 1472 C CB . ASN A 1 191 ? -52.420 -18.571 -39.479 1.00 120.96 ? 218 ASN A CB 1 ATOM 1473 C CG . ASN A 1 191 ? -53.267 -19.498 -40.350 1.00 120.71 ? 218 ASN A CG 1 ATOM 1474 O OD1 . ASN A 1 191 ? -54.487 -19.565 -40.226 1.00 124.02 ? 218 ASN A OD1 1 ATOM 1475 N ND2 . ASN A 1 191 ? -52.605 -20.200 -41.264 1.00 121.69 ? 218 ASN A ND2 1 ATOM 1476 N N . SER A 1 192 ? -54.396 -16.486 -39.331 1.00 123.44 ? 219 SER A N 1 ATOM 1477 C CA . SER A 1 192 ? -55.567 -15.639 -39.532 1.00 119.04 ? 219 SER A CA 1 ATOM 1478 C C . SER A 1 192 ? -56.760 -16.415 -40.087 1.00 119.68 ? 219 SER A C 1 ATOM 1479 O O . SER A 1 192 ? -57.885 -15.916 -40.088 1.00 119.52 ? 219 SER A O 1 ATOM 1480 C CB . SER A 1 192 ? -55.223 -14.473 -40.460 1.00 114.64 ? 219 SER A CB 1 ATOM 1481 O OG . SER A 1 192 ? -54.540 -14.928 -41.615 1.00 123.30 ? 219 SER A OG 1 ATOM 1482 N N . ALA A 1 193 ? -56.514 -17.636 -40.555 1.00 128.30 ? 220 ALA A N 1 ATOM 1483 C CA . ALA A 1 193 ? -57.593 -18.480 -41.056 1.00 135.09 ? 220 ALA A CA 1 ATOM 1484 C C . ALA A 1 193 ? -58.255 -19.352 -39.985 1.00 134.97 ? 220 ALA A C 1 ATOM 1485 O O . ALA A 1 193 ? -59.443 -19.658 -40.081 1.00 132.08 ? 220 ALA A O 1 ATOM 1486 C CB . ALA A 1 193 ? -57.072 -19.357 -42.188 1.00 138.47 ? 220 ALA A CB 1 ATOM 1487 N N . GLY A 1 194 ? -57.496 -19.747 -38.967 1.00 134.51 ? 221 GLY A N 1 ATOM 1488 C CA . GLY A 1 194 ? -58.021 -20.678 -37.982 1.00 133.80 ? 221 GLY A CA 1 ATOM 1489 C C . GLY A 1 194 ? -56.985 -21.472 -37.204 1.00 130.27 ? 221 GLY A C 1 ATOM 1490 O O . GLY A 1 194 ? -55.790 -21.176 -37.251 1.00 129.30 ? 221 GLY A O 1 ATOM 1491 N N . THR A 1 195 ? -57.452 -22.497 -36.494 1.00 126.91 ? 222 THR A N 1 ATOM 1492 C CA . THR A 1 195 ? -56.630 -23.209 -35.523 1.00 115.56 ? 222 THR A CA 1 ATOM 1493 C C . THR A 1 195 ? -56.755 -24.722 -35.735 1.00 114.03 ? 222 THR A C 1 ATOM 1494 O O . THR A 1 195 ? -57.844 -25.233 -35.993 1.00 125.19 ? 222 THR A O 1 ATOM 1495 C CB . THR A 1 195 ? -57.041 -22.846 -34.074 1.00 112.64 ? 222 THR A CB 1 ATOM 1496 O OG1 . THR A 1 195 ? -56.884 -21.437 -33.862 1.00 105.91 ? 222 THR A OG1 1 ATOM 1497 C CG2 . THR A 1 195 ? -56.204 -23.606 -33.056 1.00 118.13 ? 222 THR A CG2 1 ATOM 1498 N N . ARG A 1 196 ? -55.633 -25.431 -35.624 1.00 105.51 ? 223 ARG A N 1 ATOM 1499 C CA . ARG A 1 196 ? -55.608 -26.892 -35.705 1.00 110.86 ? 223 ARG A CA 1 ATOM 1500 C C . ARG A 1 196 ? -54.699 -27.500 -34.647 1.00 109.57 ? 223 ARG A C 1 ATOM 1501 O O . ARG A 1 196 ? -53.614 -26.989 -34.380 1.00 109.12 ? 223 ARG A O 1 ATOM 1502 C CB . ARG A 1 196 ? -55.159 -27.375 -37.092 1.00 123.61 ? 223 ARG A CB 1 ATOM 1503 C CG . ARG A 1 196 ? -55.050 -28.905 -37.178 1.00 122.18 ? 223 ARG A CG 1 ATOM 1504 C CD . ARG A 1 196 ? -54.703 -29.436 -38.562 1.00 121.73 ? 223 ARG A CD 1 ATOM 1505 N NE . ARG A 1 196 ? -55.715 -29.117 -39.564 1.00 127.97 ? 223 ARG A NE 1 ATOM 1506 C CZ . ARG A 1 196 ? -56.821 -29.832 -39.753 1.00 127.03 ? 223 ARG A CZ 1 ATOM 1507 N NH1 . ARG A 1 196 ? -57.054 -30.904 -39.008 1.00 125.97 ? 223 ARG A NH1 1 ATOM 1508 N NH2 . ARG A 1 196 ? -57.685 -29.483 -40.695 1.00 125.09 ? 223 ARG A NH2 1 ATOM 1509 N N . TYR A 1 197 ? -55.151 -28.599 -34.054 1.00 111.54 ? 224 TYR A N 1 ATOM 1510 C CA . TYR A 1 197 ? -54.362 -29.317 -33.065 1.00 110.56 ? 224 TYR A CA 1 ATOM 1511 C C . TYR A 1 197 ? -53.682 -30.544 -33.662 1.00 105.43 ? 224 TYR A C 1 ATOM 1512 O O . TYR A 1 197 ? -54.203 -31.185 -34.575 1.00 115.64 ? 224 TYR A O 1 ATOM 1513 C CB . TYR A 1 197 ? -55.229 -29.744 -31.873 1.00 112.75 ? 224 TYR A CB 1 ATOM 1514 C CG . TYR A 1 197 ? -55.595 -28.621 -30.926 1.00 109.48 ? 224 TYR A CG 1 ATOM 1515 C CD1 . TYR A 1 197 ? -56.098 -27.417 -31.401 1.00 110.74 ? 224 TYR A CD1 1 ATOM 1516 C CD2 . TYR A 1 197 ? -55.431 -28.767 -29.551 1.00 107.96 ? 224 TYR A CD2 1 ATOM 1517 C CE1 . TYR A 1 197 ? -56.427 -26.391 -30.541 1.00 116.28 ? 224 TYR A CE1 1 ATOM 1518 C CE2 . TYR A 1 197 ? -55.762 -27.746 -28.680 1.00 111.63 ? 224 TYR A CE2 1 ATOM 1519 C CZ . TYR A 1 197 ? -56.260 -26.559 -29.183 1.00 118.62 ? 224 TYR A CZ 1 ATOM 1520 O OH . TYR A 1 197 ? -56.585 -25.528 -28.336 1.00 122.99 ? 224 TYR A OH 1 ATOM 1521 N N . SER A 1 198 ? -52.500 -30.851 -33.139 1.00 92.74 ? 225 SER A N 1 ATOM 1522 C CA . SER A 1 198 ? -51.801 -32.082 -33.470 1.00 102.92 ? 225 SER A CA 1 ATOM 1523 C C . SER A 1 198 ? -52.402 -33.154 -32.581 1.00 97.32 ? 225 SER A C 1 ATOM 1524 O O . SER A 1 198 ? -53.338 -32.880 -31.829 1.00 85.73 ? 225 SER A O 1 ATOM 1525 C CB . SER A 1 198 ? -50.293 -31.956 -33.262 1.00 109.63 ? 225 SER A CB 1 ATOM 1526 O OG . SER A 1 198 ? -49.961 -31.965 -31.885 1.00 104.63 ? 225 SER A OG 1 ATOM 1527 N N . ALA A 1 199 ? -51.870 -34.368 -32.634 1.00 106.74 ? 226 ALA A N 1 ATOM 1528 C CA . ALA A 1 199 ? -52.369 -35.391 -31.733 1.00 107.23 ? 226 ALA A CA 1 ATOM 1529 C C . ALA A 1 199 ? -51.576 -35.325 -30.435 1.00 92.47 ? 226 ALA A C 1 ATOM 1530 O O . ALA A 1 199 ? -50.445 -34.835 -30.415 1.00 92.77 ? 226 ALA A O 1 ATOM 1531 C CB . ALA A 1 199 ? -52.255 -36.768 -32.375 1.00 117.36 ? 226 ALA A CB 1 ATOM 1532 N N . PRO A 1 200 ? -52.173 -35.803 -29.332 1.00 81.83 ? 227 PRO A N 1 ATOM 1533 C CA . PRO A 1 200 ? -51.477 -35.776 -28.042 1.00 78.99 ? 227 PRO A CA 1 ATOM 1534 C C . PRO A 1 200 ? -50.244 -36.677 -27.983 1.00 76.16 ? 227 PRO A C 1 ATOM 1535 O O . PRO A 1 200 ? -50.270 -37.803 -28.480 1.00 81.67 ? 227 PRO A O 1 ATOM 1536 C CB . PRO A 1 200 ? -52.559 -36.242 -27.063 1.00 86.96 ? 227 PRO A CB 1 ATOM 1537 C CG . PRO A 1 200 ? -53.449 -37.111 -27.893 1.00 84.61 ? 227 PRO A CG 1 ATOM 1538 C CD . PRO A 1 200 ? -53.521 -36.388 -29.206 1.00 84.15 ? 227 PRO A CD 1 ATOM 1539 N N . ALA A 1 201 ? -49.176 -36.173 -27.373 1.00 70.28 ? 228 ALA A N 1 ATOM 1540 C CA . ALA A 1 201 ? -48.006 -36.982 -27.049 1.00 73.50 ? 228 ALA A CA 1 ATOM 1541 C C . ALA A 1 201 ? -47.690 -36.844 -25.566 1.00 80.79 ? 228 ALA A C 1 ATOM 1542 O O . ALA A 1 201 ? -47.583 -35.733 -25.053 1.00 90.18 ? 228 ALA A O 1 ATOM 1543 C CB . ALA A 1 201 ? -46.815 -36.562 -27.892 1.00 80.22 ? 228 ALA A CB 1 ATOM 1544 N N . ASN A 1 202 ? -47.550 -37.968 -24.873 1.00 82.81 ? 229 ASN A N 1 ATOM 1545 C CA . ASN A 1 202 ? -47.164 -37.941 -23.467 1.00 79.65 ? 229 ASN A CA 1 ATOM 1546 C C . ASN A 1 202 ? -45.655 -37.704 -23.364 1.00 76.25 ? 229 ASN A C 1 ATOM 1547 O O . ASN A 1 202 ? -44.891 -38.136 -24.227 1.00 82.31 ? 229 ASN A O 1 ATOM 1548 C CB . ASN A 1 202 ? -47.585 -39.229 -22.749 1.00 83.71 ? 229 ASN A CB 1 ATOM 1549 C CG . ASN A 1 202 ? -49.064 -39.561 -22.946 1.00 87.28 ? 229 ASN A CG 1 ATOM 1550 O OD1 . ASN A 1 202 ? -49.583 -39.525 -24.063 1.00 89.64 ? 229 ASN A OD1 1 ATOM 1551 N ND2 . ASN A 1 202 ? -49.747 -39.883 -21.850 1.00 85.10 ? 229 ASN A ND2 1 ATOM 1552 N N . LEU A 1 203 ? -45.229 -37.015 -22.310 1.00 68.93 ? 230 LEU A N 1 ATOM 1553 C CA . LEU A 1 203 ? -43.815 -36.958 -21.936 1.00 67.62 ? 230 LEU A CA 1 ATOM 1554 C C . LEU A 1 203 ? -43.517 -37.779 -20.692 1.00 73.64 ? 230 LEU A C 1 ATOM 1555 O O . LEU A 1 203 ? -44.226 -37.671 -19.692 1.00 80.76 ? 230 LEU A O 1 ATOM 1556 C CB . LEU A 1 203 ? -43.387 -35.509 -21.702 1.00 62.11 ? 230 LEU A CB 1 ATOM 1557 C CG . LEU A 1 203 ? -42.060 -35.349 -20.953 1.00 62.30 ? 230 LEU A CG 1 ATOM 1558 C CD1 . LEU A 1 203 ? -40.889 -35.752 -21.830 1.00 68.11 ? 230 LEU A CD1 1 ATOM 1559 C CD2 . LEU A 1 203 ? -41.879 -33.936 -20.424 1.00 79.07 ? 230 LEU A CD2 1 ATOM 1560 N N . TYR A 1 204 ? -42.478 -38.615 -20.758 1.00 81.18 ? 231 TYR A N 1 ATOM 1561 C CA . TYR A 1 204 ? -42.076 -39.351 -19.571 1.00 85.15 ? 231 TYR A CA 1 ATOM 1562 C C . TYR A 1 204 ? -40.728 -38.800 -19.036 1.00 87.71 ? 231 TYR A C 1 ATOM 1563 O O . TYR A 1 204 ? -39.924 -38.276 -19.803 1.00 91.78 ? 231 TYR A O 1 ATOM 1564 C CB . TYR A 1 204 ? -41.985 -40.832 -19.947 1.00 79.41 ? 231 TYR A CB 1 ATOM 1565 C CG . TYR A 1 204 ? -43.344 -41.411 -20.321 1.00 74.09 ? 231 TYR A CG 1 ATOM 1566 C CD1 . TYR A 1 204 ? -44.093 -42.148 -19.420 1.00 81.63 ? 231 TYR A CD1 1 ATOM 1567 C CD2 . TYR A 1 204 ? -43.879 -41.196 -21.590 1.00 70.86 ? 231 TYR A CD2 1 ATOM 1568 C CE1 . TYR A 1 204 ? -45.333 -42.664 -19.768 1.00 79.79 ? 231 TYR A CE1 1 ATOM 1569 C CE2 . TYR A 1 204 ? -45.115 -41.704 -21.947 1.00 70.32 ? 231 TYR A CE2 1 ATOM 1570 C CZ . TYR A 1 204 ? -45.838 -42.438 -21.033 1.00 70.62 ? 231 TYR A CZ 1 ATOM 1571 O OH . TYR A 1 204 ? -47.067 -42.947 -21.387 1.00 60.76 ? 231 TYR A OH 1 ATOM 1572 N N . VAL A 1 205 ? -40.494 -38.925 -17.726 1.00 82.80 ? 232 VAL A N 1 ATOM 1573 C CA . VAL A 1 205 ? -39.282 -38.418 -17.048 1.00 82.61 ? 232 VAL A CA 1 ATOM 1574 C C . VAL A 1 205 ? -38.562 -39.413 -16.121 1.00 84.48 ? 232 VAL A C 1 ATOM 1575 O O . VAL A 1 205 ? -39.156 -39.820 -15.124 1.00 84.77 ? 232 VAL A O 1 ATOM 1576 C CB . VAL A 1 205 ? -39.591 -37.134 -16.224 1.00 86.40 ? 232 VAL A CB 1 ATOM 1577 C CG1 . VAL A 1 205 ? -38.453 -36.810 -15.265 1.00 95.98 ? 232 VAL A CG1 1 ATOM 1578 C CG2 . VAL A 1 205 ? -39.840 -35.955 -17.145 1.00 87.56 ? 232 VAL A CG2 1 ATOM 1579 N N . ARG A 1 206 ? -37.347 -39.870 -16.418 1.00 90.61 ? 233 ARG A N 1 ATOM 1580 C CA . ARG A 1 206 ? -36.776 -40.851 -15.487 1.00 102.49 ? 233 ARG A CA 1 ATOM 1581 C C . ARG A 1 206 ? -35.721 -40.248 -14.567 1.00 116.52 ? 233 ARG A C 1 ATOM 1582 O O . ARG A 1 206 ? -35.219 -39.156 -14.799 1.00 117.82 ? 233 ARG A O 1 ATOM 1583 C CB . ARG A 1 206 ? -36.151 -42.038 -16.219 1.00 114.20 ? 233 ARG A CB 1 ATOM 1584 C CG . ARG A 1 206 ? -37.074 -43.221 -16.286 1.00 126.10 ? 233 ARG A CG 1 ATOM 1585 C CD . ARG A 1 206 ? -37.072 -43.880 -17.638 1.00 139.58 ? 233 ARG A CD 1 ATOM 1586 N NE . ARG A 1 206 ? -35.728 -44.199 -18.115 1.00 142.68 ? 233 ARG A NE 1 ATOM 1587 C CZ . ARG A 1 206 ? -35.125 -45.364 -17.890 1.00 143.41 ? 233 ARG A CZ 1 ATOM 1588 N NH1 . ARG A 1 206 ? -35.726 -46.289 -17.160 1.00 142.95 ? 233 ARG A NH1 1 ATOM 1589 N NH2 . ARG A 1 206 ? -33.903 -45.588 -18.342 1.00 139.85 ? 233 ARG A NH2 1 ATOM 1590 N N . GLU A 1 207 ? -35.449 -40.961 -13.481 1.00 128.77 ? 234 GLU A N 1 ATOM 1591 C CA . GLU A 1 207 ? -34.552 -40.503 -12.421 1.00 137.05 ? 234 GLU A CA 1 ATOM 1592 C C . GLU A 1 207 ? -33.093 -40.271 -12.849 1.00 134.71 ? 234 GLU A C 1 ATOM 1593 O O . GLU A 1 207 ? -32.560 -39.169 -12.703 1.00 129.82 ? 234 GLU A O 1 ATOM 1594 C CB . GLU A 1 207 ? -34.626 -41.480 -11.246 1.00 129.83 ? 234 GLU A CB 1 ATOM 1595 C CG . GLU A 1 207 ? -36.006 -41.442 -10.575 1.00 133.96 ? 234 GLU A CG 1 ATOM 1596 C CD . GLU A 1 207 ? -36.276 -40.158 -9.793 1.00 139.40 ? 234 GLU A CD 1 ATOM 1597 O OE1 . GLU A 1 207 ? -35.386 -39.282 -9.730 1.00 142.05 ? 234 GLU A OE1 1 ATOM 1598 O OE2 . GLU A 1 207 ? -37.403 -40.004 -9.271 1.00 141.36 ? 234 GLU A OE2 1 ATOM 1599 N N . LEU A 1 208 ? -32.456 -41.322 -13.367 1.00 136.25 ? 235 LEU A N 1 ATOM 1600 C CA . LEU A 1 208 ? -31.074 -41.252 -13.847 1.00 138.20 ? 235 LEU A CA 1 ATOM 1601 C C . LEU A 1 208 ? -30.810 -42.110 -15.086 1.00 139.10 ? 235 LEU A C 1 ATOM 1602 O O . LEU A 1 208 ? -31.531 -43.076 -15.347 1.00 140.84 ? 235 LEU A O 1 ATOM 1603 C CB . LEU A 1 208 ? -30.112 -41.686 -12.735 1.00 136.67 ? 235 LEU A CB 1 ATOM 1604 C CG . LEU A 1 208 ? -28.672 -41.171 -12.791 1.00 124.81 ? 235 LEU A CG 1 ATOM 1605 C CD1 . LEU A 1 208 ? -28.567 -39.785 -12.178 1.00 122.52 ? 235 LEU A CD1 1 ATOM 1606 C CD2 . LEU A 1 208 ? -27.711 -42.144 -12.117 1.00 111.37 ? 235 LEU A CD2 1 ATOM 1607 N N . ARG A 1 209 ? -29.770 -41.752 -15.843 1.00 137.43 ? 236 ARG A N 1 ATOM 1608 C CA . ARG A 1 209 ? -29.254 -42.626 -16.894 1.00 144.76 ? 236 ARG A CA 1 ATOM 1609 C C . ARG A 1 209 ? -28.413 -43.713 -16.254 1.00 141.05 ? 236 ARG A C 1 ATOM 1610 O O . ARG A 1 209 ? -27.811 -43.501 -15.198 1.00 132.67 ? 236 ARG A O 1 ATOM 1611 C CB . ARG A 1 209 ? -28.424 -41.857 -17.942 1.00 142.10 ? 236 ARG A CB 1 ATOM 1612 C CG . ARG A 1 209 ? -29.210 -41.097 -19.038 1.00 142.94 ? 236 ARG A CG 1 ATOM 1613 C CD . ARG A 1 209 ? -30.341 -41.903 -19.688 1.00 149.57 ? 236 ARG A CD 1 ATOM 1614 N NE . ARG A 1 209 ? -31.567 -41.887 -18.890 1.00 154.45 ? 236 ARG A NE 1 ATOM 1615 C CZ . ARG A 1 209 ? -32.112 -42.969 -18.345 1.00 150.86 ? 236 ARG A CZ 1 ATOM 1616 N NH1 . ARG A 1 209 ? -31.535 -44.151 -18.519 1.00 145.92 ? 236 ARG A NH1 1 ATOM 1617 N NH2 . ARG A 1 209 ? -33.216 -42.865 -17.619 1.00 142.20 ? 236 ARG A NH2 1 ATOM 1618 N N . GLU A 1 210 ? -28.402 -44.882 -16.885 1.00 142.39 ? 237 GLU A N 1 ATOM 1619 C CA . GLU A 1 210 ? -27.519 -45.968 -16.490 1.00 135.09 ? 237 GLU A CA 1 ATOM 1620 C C . GLU A 1 210 ? -26.096 -45.415 -16.420 1.00 133.79 ? 237 GLU A C 1 ATOM 1621 O O . GLU A 1 210 ? -25.450 -45.466 -15.373 1.00 130.52 ? 237 GLU A O 1 ATOM 1622 C CB . GLU A 1 210 ? -27.627 -47.131 -17.482 1.00 130.53 ? 237 GLU A CB 1 ATOM 1623 C CG . GLU A 1 210 ? -28.936 -47.146 -18.277 1.00 125.22 ? 237 GLU A CG 1 ATOM 1624 C CD . GLU A 1 210 ? -30.019 -48.002 -17.641 1.00 112.61 ? 237 GLU A CD 1 ATOM 1625 O OE1 . GLU A 1 210 ? -31.030 -47.440 -17.160 1.00 104.69 ? 237 GLU A OE1 1 ATOM 1626 O OE2 . GLU A 1 210 ? -29.866 -49.243 -17.631 1.00 112.17 ? 237 GLU A OE2 1 ATOM 1627 N N . VAL A 1 211 ? -25.637 -44.872 -17.547 1.00 135.81 ? 238 VAL A N 1 ATOM 1628 C CA . VAL A 1 211 ? -24.438 -44.036 -17.632 1.00 133.24 ? 238 VAL A CA 1 ATOM 1629 C C . VAL A 1 211 ? -24.694 -42.970 -18.705 1.00 138.72 ? 238 VAL A C 1 ATOM 1630 O O . VAL A 1 211 ? -25.388 -43.241 -19.686 1.00 149.02 ? 238 VAL A O 1 ATOM 1631 C CB . VAL A 1 211 ? -23.162 -44.852 -17.988 1.00 122.93 ? 238 VAL A CB 1 ATOM 1632 C CG1 . VAL A 1 211 ? -21.967 -43.932 -18.180 1.00 113.26 ? 238 VAL A CG1 1 ATOM 1633 C CG2 . VAL A 1 211 ? -22.849 -45.891 -16.921 1.00 123.62 ? 238 VAL A CG2 1 ATOM 1634 N N . ARG A 1 212 ? -24.166 -41.761 -18.524 1.00 131.54 ? 239 ARG A N 1 ATOM 1635 C CA . ARG A 1 212 ? -24.309 -40.719 -19.542 1.00 131.80 ? 239 ARG A CA 1 ATOM 1636 C C . ARG A 1 212 ? -23.170 -40.758 -20.563 1.00 135.20 ? 239 ARG A C 1 ATOM 1637 O O . ARG A 1 212 ? -22.246 -41.566 -20.455 1.00 124.81 ? 239 ARG A O 1 ATOM 1638 C CB . ARG A 1 212 ? -24.381 -39.331 -18.900 1.00 122.80 ? 239 ARG A CB 1 ATOM 1639 C CG . ARG A 1 212 ? -25.711 -38.624 -19.111 1.00 113.77 ? 239 ARG A CG 1 ATOM 1640 C CD . ARG A 1 212 ? -25.519 -37.121 -19.205 1.00 121.21 ? 239 ARG A CD 1 ATOM 1641 N NE . ARG A 1 212 ? -26.596 -36.385 -18.548 1.00 126.56 ? 239 ARG A NE 1 ATOM 1642 C CZ . ARG A 1 212 ? -26.572 -35.077 -18.314 1.00 120.93 ? 239 ARG A CZ 1 ATOM 1643 N NH1 . ARG A 1 212 ? -25.523 -34.357 -18.686 1.00 123.64 ? 239 ARG A NH1 1 ATOM 1644 N NH2 . ARG A 1 212 ? -27.592 -34.490 -17.703 1.00 112.50 ? 239 ARG A NH2 1 ATOM 1645 N N . ARG A 1 213 ? -23.248 -39.873 -21.552 1.00 139.14 ? 240 ARG A N 1 ATOM 1646 C CA . ARG A 1 213 ? -22.265 -39.816 -22.627 1.00 136.85 ? 240 ARG A CA 1 ATOM 1647 C C . ARG A 1 213 ? -20.917 -39.311 -22.123 1.00 135.67 ? 240 ARG A C 1 ATOM 1648 O O . ARG A 1 213 ? -20.834 -38.676 -21.074 1.00 137.39 ? 240 ARG A O 1 ATOM 1649 C CB . ARG A 1 213 ? -22.766 -38.917 -23.759 1.00 144.07 ? 240 ARG A CB 1 ATOM 1650 C CG . ARG A 1 213 ? -24.164 -39.249 -24.244 1.00 146.18 ? 240 ARG A CG 1 ATOM 1651 C CD . ARG A 1 213 ? -24.755 -38.090 -25.027 1.00 147.95 ? 240 ARG A CD 1 ATOM 1652 N NE . ARG A 1 213 ? -26.163 -38.306 -25.348 1.00 147.39 ? 240 ARG A NE 1 ATOM 1653 C CZ . ARG A 1 213 ? -26.982 -37.357 -25.788 1.00 150.16 ? 240 ARG A CZ 1 ATOM 1654 N NH1 . ARG A 1 213 ? -26.535 -36.120 -25.957 1.00 146.30 ? 240 ARG A NH1 1 ATOM 1655 N NH2 . ARG A 1 213 ? -28.249 -37.644 -26.055 1.00 153.52 ? 240 ARG A NH2 1 ATOM 1656 N N . VAL A 1 214 ? -19.865 -39.585 -22.886 1.00 137.17 ? 241 VAL A N 1 ATOM 1657 C CA . VAL A 1 214 ? -18.512 -39.188 -22.512 1.00 136.22 ? 241 VAL A CA 1 ATOM 1658 C C . VAL A 1 214 ? -17.985 -38.098 -23.447 1.00 137.40 ? 241 VAL A C 1 ATOM 1659 O O . VAL A 1 214 ? -17.995 -38.267 -24.665 1.00 140.67 ? 241 VAL A O 1 ATOM 1660 C CB . VAL A 1 214 ? -17.559 -40.395 -22.532 1.00 132.12 ? 241 VAL A CB 1 ATOM 1661 C CG1 . VAL A 1 214 ? -16.142 -39.956 -22.251 1.00 127.33 ? 241 VAL A CG1 1 ATOM 1662 C CG2 . VAL A 1 214 ? -18.012 -41.455 -21.539 1.00 129.68 ? 241 VAL A CG2 1 ATOM 1663 N N . PRO A 1 215 ? -17.534 -36.965 -22.884 1.00 133.90 ? 242 PRO A N 1 ATOM 1664 C CA . PRO A 1 215 ? -16.959 -35.990 -23.813 1.00 128.95 ? 242 PRO A CA 1 ATOM 1665 C C . PRO A 1 215 ? -15.636 -36.474 -24.404 1.00 123.81 ? 242 PRO A C 1 ATOM 1666 O O . PRO A 1 215 ? -15.003 -37.358 -23.830 1.00 125.68 ? 242 PRO A O 1 ATOM 1667 C CB . PRO A 1 215 ? -16.708 -34.774 -22.914 1.00 133.13 ? 242 PRO A CB 1 ATOM 1668 C CG . PRO A 1 215 ? -17.740 -34.890 -21.840 1.00 129.11 ? 242 PRO A CG 1 ATOM 1669 C CD . PRO A 1 215 ? -17.815 -36.373 -21.563 1.00 131.96 ? 242 PRO A CD 1 ATOM 1670 N N . PRO A 1 216 ? -15.232 -35.922 -25.556 1.00 118.55 ? 243 PRO A N 1 ATOM 1671 C CA . PRO A 1 216 ? -14.022 -36.421 -26.216 1.00 129.10 ? 243 PRO A CA 1 ATOM 1672 C C . PRO A 1 216 ? -12.764 -36.105 -25.403 1.00 138.04 ? 243 PRO A C 1 ATOM 1673 O O . PRO A 1 216 ? -12.723 -35.054 -24.763 1.00 141.10 ? 243 PRO A O 1 ATOM 1674 C CB . PRO A 1 216 ? -14.026 -35.682 -27.555 1.00 140.00 ? 243 PRO A CB 1 ATOM 1675 C CG . PRO A 1 216 ? -14.761 -34.432 -27.273 1.00 138.84 ? 243 PRO A CG 1 ATOM 1676 C CD . PRO A 1 216 ? -15.857 -34.832 -26.325 1.00 124.12 ? 243 PRO A CD 1 ATOM 1677 N N . ARG A 1 217 ? -11.764 -36.981 -25.413 1.00 145.21 ? 244 ARG A N 1 ATOM 1678 C CA . ARG A 1 217 ? -10.550 -36.739 -24.632 1.00 147.55 ? 244 ARG A CA 1 ATOM 1679 C C . ARG A 1 217 ? -9.380 -37.440 -25.313 1.00 153.52 ? 244 ARG A C 1 ATOM 1680 O O . ARG A 1 217 ? -9.556 -38.484 -25.943 1.00 159.61 ? 244 ARG A O 1 ATOM 1681 C CB . ARG A 1 217 ? -10.705 -37.200 -23.181 1.00 146.50 ? 244 ARG A CB 1 ATOM 1682 C CG . ARG A 1 217 ? -10.484 -38.681 -22.929 1.00 145.26 ? 244 ARG A CG 1 ATOM 1683 C CD . ARG A 1 217 ? -10.552 -38.975 -21.439 1.00 128.15 ? 244 ARG A CD 1 ATOM 1684 N NE . ARG A 1 217 ? -11.437 -38.041 -20.748 1.00 118.42 ? 244 ARG A NE 1 ATOM 1685 C CZ . ARG A 1 217 ? -12.744 -38.220 -20.607 1.00 110.75 ? 244 ARG A CZ 1 ATOM 1686 N NH1 . ARG A 1 217 ? -13.312 -39.304 -21.107 1.00 112.46 ? 244 ARG A NH1 1 ATOM 1687 N NH2 . ARG A 1 217 ? -13.480 -37.319 -19.972 1.00 105.62 ? 244 ARG A NH2 1 ATOM 1688 N N . PHE A 1 218 ? -8.191 -36.853 -25.213 1.00 147.02 ? 245 PHE A N 1 ATOM 1689 C CA . PHE A 1 218 ? -7.009 -37.454 -25.825 1.00 152.12 ? 245 PHE A CA 1 ATOM 1690 C C . PHE A 1 218 ? -6.307 -38.609 -25.121 1.00 154.78 ? 245 PHE A C 1 ATOM 1691 O O . PHE A 1 218 ? -5.734 -38.466 -24.040 1.00 158.85 ? 245 PHE A O 1 ATOM 1692 C CB . PHE A 1 218 ? -5.964 -36.374 -26.102 1.00 153.72 ? 245 PHE A CB 1 ATOM 1693 C CG . PHE A 1 218 ? -6.346 -35.446 -27.212 1.00 157.25 ? 245 PHE A CG 1 ATOM 1694 C CD1 . PHE A 1 218 ? -6.244 -35.863 -28.527 1.00 154.84 ? 245 PHE A CD1 1 ATOM 1695 C CD2 . PHE A 1 218 ? -6.780 -34.158 -26.954 1.00 165.52 ? 245 PHE A CD2 1 ATOM 1696 C CE1 . PHE A 1 218 ? -6.589 -35.026 -29.561 1.00 157.41 ? 245 PHE A CE1 1 ATOM 1697 C CE2 . PHE A 1 218 ? -7.120 -33.308 -27.991 1.00 167.04 ? 245 PHE A CE2 1 ATOM 1698 C CZ . PHE A 1 218 ? -7.024 -33.746 -29.298 1.00 164.04 ? 245 PHE A CZ 1 ATOM 1699 N N . SER A 1 219 ? -6.376 -39.758 -25.779 1.00 155.91 ? 246 SER A N 1 ATOM 1700 C CA . SER A 1 219 ? -5.732 -40.995 -25.367 1.00 150.96 ? 246 SER A CA 1 ATOM 1701 C C . SER A 1 219 ? -4.232 -40.919 -25.675 1.00 158.93 ? 246 SER A C 1 ATOM 1702 O O . SER A 1 219 ? -3.393 -41.328 -24.873 1.00 156.90 ? 246 SER A O 1 ATOM 1703 C CB . SER A 1 219 ? -6.365 -42.197 -26.054 1.00 150.30 ? 246 SER A CB 1 ATOM 1704 O OG . SER A 1 219 ? -6.118 -42.135 -27.431 1.00 154.01 ? 246 SER A OG 1 ATOM 1705 N N . ILE A 1 220 ? -3.932 -40.401 -26.872 1.00 170.28 ? 247 ILE A N 1 ATOM 1706 C CA . ILE A 1 220 ? -2.566 -40.191 -27.372 1.00 178.55 ? 247 ILE A CA 1 ATOM 1707 C C . ILE A 1 220 ? -2.368 -38.803 -27.993 1.00 180.65 ? 247 ILE A C 1 ATOM 1708 O O . ILE A 1 220 ? -2.574 -38.612 -29.198 1.00 181.13 ? 247 ILE A O 1 ATOM 1709 C CB . ILE A 1 220 ? -2.186 -41.212 -28.476 1.00 177.14 ? 247 ILE A CB 1 ATOM 1710 C CG1 . ILE A 1 220 ? -2.445 -42.657 -28.064 1.00 175.63 ? 247 ILE A CG1 1 ATOM 1711 C CG2 . ILE A 1 220 ? -0.739 -41.008 -28.950 1.00 181.58 ? 247 ILE A CG2 1 ATOM 1712 C CD1 . ILE A 1 220 ? -2.079 -43.625 -29.171 1.00 179.73 ? 247 ILE A CD1 1 ATOM 1713 N N . PRO A 1 221 ? -2.020 -37.811 -27.154 1.00 174.76 ? 248 PRO A N 1 ATOM 1714 C CA . PRO A 1 221 ? -1.713 -36.445 -27.611 1.00 175.48 ? 248 PRO A CA 1 ATOM 1715 C C . PRO A 1 221 ? -0.598 -36.398 -28.671 1.00 180.73 ? 248 PRO A C 1 ATOM 1716 O O . PRO A 1 221 ? 0.108 -37.386 -28.857 1.00 180.00 ? 248 PRO A O 1 ATOM 1717 C CB . PRO A 1 221 ? -1.258 -35.728 -26.310 1.00 168.08 ? 248 PRO A CB 1 ATOM 1718 C CG . PRO A 1 221 ? -1.122 -36.819 -25.277 1.00 158.72 ? 248 PRO A CG 1 ATOM 1719 C CD . PRO A 1 221 ? -2.031 -37.916 -25.686 1.00 161.87 ? 248 PRO A CD 1 ATOM 1720 N N . PRO A 1 222 ? -0.459 -35.258 -29.373 1.00 181.11 ? 249 PRO A N 1 ATOM 1721 C CA . PRO A 1 222 ? 0.460 -35.093 -30.510 1.00 184.30 ? 249 PRO A CA 1 ATOM 1722 C C . PRO A 1 222 ? 1.804 -34.465 -30.111 1.00 197.77 ? 249 PRO A C 1 ATOM 1723 O O . PRO A 1 222 ? 1.844 -33.311 -29.658 1.00 196.48 ? 249 PRO A O 1 ATOM 1724 C CB . PRO A 1 222 ? -0.331 -34.196 -31.458 1.00 181.57 ? 249 PRO A CB 1 ATOM 1725 C CG . PRO A 1 222 ? -1.140 -33.348 -30.564 1.00 174.18 ? 249 PRO A CG 1 ATOM 1726 C CD . PRO A 1 222 ? -1.437 -34.150 -29.320 1.00 173.99 ? 249 PRO A CD 1 ATOM 1727 N N . THR A 1 223 ? 2.900 -35.213 -30.257 1.00 207.07 ? 250 THR A N 1 ATOM 1728 C CA . THR A 1 223 ? 4.143 -34.825 -29.598 1.00 208.60 ? 250 THR A CA 1 ATOM 1729 C C . THR A 1 223 ? 5.172 -34.072 -30.447 1.00 207.11 ? 250 THR A C 1 ATOM 1730 O O . THR A 1 223 ? 5.385 -34.387 -31.626 1.00 208.74 ? 250 THR A O 1 ATOM 1731 C CB . THR A 1 223 ? 4.851 -36.094 -29.050 1.00 197.20 ? 250 THR A CB 1 ATOM 1732 O OG1 . THR A 1 223 ? 4.734 -37.180 -29.984 1.00 196.48 ? 250 THR A OG1 1 ATOM 1733 C CG2 . THR A 1 223 ? 4.263 -36.511 -27.705 1.00 179.09 ? 250 THR A CG2 1 ATOM 1734 N N . ASN A 1 224 ? 5.776 -33.047 -29.838 1.00 202.54 ? 251 ASN A N 1 ATOM 1735 C CA . ASN A 1 224 ? 6.566 -32.080 -30.590 1.00 190.03 ? 251 ASN A CA 1 ATOM 1736 C C . ASN A 1 224 ? 7.757 -32.798 -31.228 1.00 197.51 ? 251 ASN A C 1 ATOM 1737 O O . ASN A 1 224 ? 8.125 -33.896 -30.814 1.00 201.95 ? 251 ASN A O 1 ATOM 1738 C CB . ASN A 1 224 ? 7.036 -30.923 -29.701 1.00 174.32 ? 251 ASN A CB 1 ATOM 1739 C CG . ASN A 1 224 ? 6.024 -29.779 -29.628 1.00 167.87 ? 251 ASN A CG 1 ATOM 1740 O OD1 . ASN A 1 224 ? 5.065 -29.728 -30.396 1.00 167.78 ? 251 ASN A OD1 1 ATOM 1741 N ND2 . ASN A 1 224 ? 6.250 -28.848 -28.706 1.00 167.15 ? 251 ASN A ND2 1 ATOM 1742 N N . HIS A 1 225 ? 8.400 -32.137 -32.177 1.00 199.89 ? 252 HIS A N 1 ATOM 1743 C CA . HIS A 1 225 ? 9.557 -32.668 -32.897 1.00 208.06 ? 252 HIS A CA 1 ATOM 1744 C C . HIS A 1 225 ? 10.593 -31.649 -33.353 1.00 206.23 ? 252 HIS A C 1 ATOM 1745 O O . HIS A 1 225 ? 10.309 -30.469 -33.574 1.00 205.85 ? 252 HIS A O 1 ATOM 1746 C CB . HIS A 1 225 ? 9.111 -33.556 -34.076 1.00 208.24 ? 252 HIS A CB 1 ATOM 1747 C CG . HIS A 1 225 ? 8.364 -34.791 -33.664 1.00 212.22 ? 252 HIS A CG 1 ATOM 1748 N ND1 . HIS A 1 225 ? 8.744 -35.559 -32.588 1.00 211.17 ? 252 HIS A ND1 1 ATOM 1749 C CD2 . HIS A 1 225 ? 7.239 -35.366 -34.146 1.00 205.77 ? 252 HIS A CD2 1 ATOM 1750 C CE1 . HIS A 1 225 ? 7.920 -36.583 -32.457 1.00 202.24 ? 252 HIS A CE1 1 ATOM 1751 N NE2 . HIS A 1 225 ? 6.988 -36.483 -33.385 1.00 199.17 ? 252 HIS A NE2 1 ATOM 1752 N N . GLU A 1 226 ? 11.807 -32.159 -33.496 1.00 202.73 ? 253 GLU A N 1 ATOM 1753 C CA . GLU A 1 226 ? 12.831 -31.511 -34.282 1.00 198.50 ? 253 GLU A CA 1 ATOM 1754 C C . GLU A 1 226 ? 13.198 -32.584 -35.284 1.00 198.23 ? 253 GLU A C 1 ATOM 1755 O O . GLU A 1 226 ? 13.392 -33.750 -34.934 1.00 195.27 ? 253 GLU A O 1 ATOM 1756 C CB . GLU A 1 226 ? 14.026 -31.080 -33.437 1.00 198.76 ? 253 GLU A CB 1 ATOM 1757 C CG . GLU A 1 226 ? 15.141 -30.453 -34.247 1.00 200.90 ? 253 GLU A CG 1 ATOM 1758 C CD . GLU A 1 226 ? 16.514 -30.862 -33.759 1.00 204.86 ? 253 GLU A CD 1 ATOM 1759 O OE1 . GLU A 1 226 ? 16.727 -30.904 -32.528 1.00 204.49 ? 253 GLU A OE1 1 ATOM 1760 O OE2 . GLU A 1 226 ? 17.383 -31.134 -34.612 1.00 201.57 ? 253 GLU A OE2 1 ATOM 1761 N N . ILE A 1 227 ? 13.303 -32.161 -36.539 1.00 199.87 ? 254 ILE A N 1 ATOM 1762 C CA . ILE A 1 227 ? 13.802 -32.984 -37.630 1.00 199.48 ? 254 ILE A CA 1 ATOM 1763 C C . ILE A 1 227 ? 14.598 -32.164 -38.637 1.00 198.42 ? 254 ILE A C 1 ATOM 1764 O O . ILE A 1 227 ? 14.430 -30.952 -38.748 1.00 199.94 ? 254 ILE A O 1 ATOM 1765 C CB . ILE A 1 227 ? 12.621 -33.669 -38.406 1.00 196.56 ? 254 ILE A CB 1 ATOM 1766 C CG1 . ILE A 1 227 ? 11.464 -34.058 -37.474 1.00 196.36 ? 254 ILE A CG1 1 ATOM 1767 C CG2 . ILE A 1 227 ? 13.101 -34.873 -39.204 1.00 186.62 ? 254 ILE A CG2 1 ATOM 1768 C CD1 . ILE A 1 227 ? 10.088 -33.927 -38.106 1.00 196.74 ? 254 ILE A CD1 1 ATOM 1769 N N . MET A 1 228 ? 15.474 -32.853 -39.359 1.00 192.26 ? 255 MET A N 1 ATOM 1770 C CA . MET A 1 228 ? 16.269 -32.277 -40.435 1.00 196.31 ? 255 MET A CA 1 ATOM 1771 C C . MET A 1 228 ? 15.415 -31.779 -41.603 1.00 198.01 ? 255 MET A C 1 ATOM 1772 O O . MET A 1 228 ? 14.296 -32.260 -41.798 1.00 197.45 ? 255 MET A O 1 ATOM 1773 C CB . MET A 1 228 ? 17.269 -33.326 -40.928 1.00 194.27 ? 255 MET A CB 1 ATOM 1774 C CG . MET A 1 228 ? 18.453 -33.493 -40.005 1.00 199.06 ? 255 MET A CG 1 ATOM 1775 S SD . MET A 1 228 ? 18.793 -31.951 -39.141 1.00 207.93 ? 255 MET A SD 1 ATOM 1776 C CE . MET A 1 228 ? 18.552 -32.435 -37.434 1.00 192.71 ? 255 MET A CE 1 ATOM 1777 N N . PRO A 1 229 ? 15.934 -30.799 -42.373 1.00 200.79 ? 256 PRO A N 1 ATOM 1778 C CA . PRO A 1 229 ? 15.120 -30.192 -43.432 1.00 196.30 ? 256 PRO A CA 1 ATOM 1779 C C . PRO A 1 229 ? 14.798 -31.201 -44.530 1.00 195.71 ? 256 PRO A C 1 ATOM 1780 O O . PRO A 1 229 ? 15.647 -31.516 -45.364 1.00 192.36 ? 256 PRO A O 1 ATOM 1781 C CB . PRO A 1 229 ? 16.007 -29.056 -43.972 1.00 185.74 ? 256 PRO A CB 1 ATOM 1782 C CG . PRO A 1 229 ? 17.112 -28.891 -42.983 1.00 184.65 ? 256 PRO A CG 1 ATOM 1783 C CD . PRO A 1 229 ? 17.285 -30.212 -42.312 1.00 196.58 ? 256 PRO A CD 1 ATOM 1784 N N . GLY A 1 230 ? 13.571 -31.709 -44.506 1.00 195.73 ? 257 GLY A N 1 ATOM 1785 C CA . GLY A 1 230 ? 13.163 -32.784 -45.388 1.00 191.27 ? 257 GLY A CA 1 ATOM 1786 C C . GLY A 1 230 ? 13.625 -34.142 -44.895 1.00 190.84 ? 257 GLY A C 1 ATOM 1787 O O . GLY A 1 230 ? 14.486 -34.776 -45.505 1.00 182.81 ? 257 GLY A O 1 ATOM 1788 N N . GLY A 1 231 ? 13.049 -34.583 -43.781 1.00 196.17 ? 258 GLY A N 1 ATOM 1789 C CA . GLY A 1 231 ? 13.264 -35.921 -43.256 1.00 197.77 ? 258 GLY A CA 1 ATOM 1790 C C . GLY A 1 231 ? 11.903 -36.577 -43.159 1.00 197.64 ? 258 GLY A C 1 ATOM 1791 O O . GLY A 1 231 ? 10.938 -36.038 -43.681 1.00 192.99 ? 258 GLY A O 1 ATOM 1792 N N . SER A 1 232 ? 11.780 -37.699 -42.461 1.00 203.21 ? 259 SER A N 1 ATOM 1793 C CA . SER A 1 232 ? 10.444 -38.268 -42.304 1.00 206.86 ? 259 SER A CA 1 ATOM 1794 C C . SER A 1 232 ? 10.117 -38.593 -40.852 1.00 208.14 ? 259 SER A C 1 ATOM 1795 O O . SER A 1 232 ? 11.004 -38.833 -40.031 1.00 207.42 ? 259 SER A O 1 ATOM 1796 C CB . SER A 1 232 ? 10.292 -39.521 -43.172 1.00 203.06 ? 259 SER A CB 1 ATOM 1797 O OG . SER A 1 232 ? 8.930 -39.902 -43.292 1.00 202.55 ? 259 SER A OG 1 ATOM 1798 N N . VAL A 1 233 ? 8.821 -38.606 -40.559 1.00 201.40 ? 260 VAL A N 1 ATOM 1799 C CA . VAL A 1 233 ? 8.307 -38.763 -39.199 1.00 190.41 ? 260 VAL A CA 1 ATOM 1800 C C . VAL A 1 233 ? 6.846 -39.220 -39.244 1.00 184.68 ? 260 VAL A C 1 ATOM 1801 O O . VAL A 1 233 ? 6.060 -38.748 -40.070 1.00 185.08 ? 260 VAL A O 1 ATOM 1802 C CB . VAL A 1 233 ? 8.462 -37.465 -38.362 1.00 186.80 ? 260 VAL A CB 1 ATOM 1803 C CG1 . VAL A 1 233 ? 7.436 -36.410 -38.757 1.00 187.87 ? 260 VAL A CG1 1 ATOM 1804 C CG2 . VAL A 1 233 ? 8.380 -37.781 -36.870 1.00 186.34 ? 260 VAL A CG2 1 ATOM 1805 N N . ASN A 1 234 ? 6.495 -40.174 -38.387 1.00 184.29 ? 261 ASN A N 1 ATOM 1806 C CA . ASN A 1 234 ? 5.113 -40.629 -38.289 1.00 180.93 ? 261 ASN A CA 1 ATOM 1807 C C . ASN A 1 234 ? 4.455 -40.075 -37.025 1.00 180.17 ? 261 ASN A C 1 ATOM 1808 O O . ASN A 1 234 ? 4.770 -40.519 -35.919 1.00 175.61 ? 261 ASN A O 1 ATOM 1809 C CB . ASN A 1 234 ? 5.063 -42.159 -38.253 1.00 168.99 ? 261 ASN A CB 1 ATOM 1810 C CG . ASN A 1 234 ? 5.162 -42.782 -39.628 1.00 170.87 ? 261 ASN A CG 1 ATOM 1811 O OD1 . ASN A 1 234 ? 4.792 -42.169 -40.623 1.00 172.98 ? 261 ASN A OD1 1 ATOM 1812 N ND2 . ASN A 1 234 ? 5.655 -44.013 -39.688 1.00 166.76 ? 261 ASN A ND2 1 ATOM 1813 N N . ILE A 1 235 ? 3.532 -39.123 -37.174 1.00 181.61 ? 262 ILE A N 1 ATOM 1814 C CA . ILE A 1 235 ? 2.865 -38.577 -35.995 1.00 180.21 ? 262 ILE A CA 1 ATOM 1815 C C . ILE A 1 235 ? 1.446 -39.098 -35.797 1.00 173.31 ? 262 ILE A C 1 ATOM 1816 O O . ILE A 1 235 ? 0.571 -38.925 -36.645 1.00 166.93 ? 262 ILE A O 1 ATOM 1817 C CB . ILE A 1 235 ? 2.793 -37.034 -36.070 1.00 178.53 ? 262 ILE A CB 1 ATOM 1818 C CG1 . ILE A 1 235 ? 4.181 -36.439 -36.313 1.00 186.23 ? 262 ILE A CG1 1 ATOM 1819 C CG2 . ILE A 1 235 ? 2.157 -36.463 -34.808 1.00 172.62 ? 262 ILE A CG2 1 ATOM 1820 C CD1 . ILE A 1 235 ? 4.177 -34.935 -36.488 1.00 188.50 ? 262 ILE A CD1 1 ATOM 1821 N N . THR A 1 236 ? 1.243 -39.731 -34.647 1.00 175.57 ? 263 THR A N 1 ATOM 1822 C CA . THR A 1 236 ? 0.005 -40.430 -34.335 1.00 165.59 ? 263 THR A CA 1 ATOM 1823 C C . THR A 1 236 ? -0.918 -39.659 -33.398 1.00 157.74 ? 263 THR A C 1 ATOM 1824 O O . THR A 1 236 ? -0.462 -39.120 -32.392 1.00 154.93 ? 263 THR A O 1 ATOM 1825 C CB . THR A 1 236 ? 0.296 -41.802 -33.693 1.00 170.18 ? 263 THR A CB 1 ATOM 1826 O OG1 . THR A 1 236 ? 0.473 -41.646 -32.280 1.00 183.45 ? 263 THR A OG1 1 ATOM 1827 C CG2 . THR A 1 236 ? 1.546 -42.423 -34.301 1.00 168.64 ? 263 THR A CG2 1 ATOM 1828 N N . CYS A 1 237 ? -2.204 -39.579 -33.717 1.00 157.97 ? 264 CYS A N 1 ATOM 1829 C CA . CYS A 1 237 ? -3.117 -38.935 -32.785 1.00 160.79 ? 264 CYS A CA 1 ATOM 1830 C C . CYS A 1 237 ? -4.255 -39.919 -32.559 1.00 164.71 ? 264 CYS A C 1 ATOM 1831 O O . CYS A 1 237 ? -4.788 -40.479 -33.516 1.00 166.48 ? 264 CYS A O 1 ATOM 1832 C CB . CYS A 1 237 ? -3.630 -37.598 -33.314 1.00 161.14 ? 264 CYS A CB 1 ATOM 1833 S SG . CYS A 1 237 ? -4.744 -36.741 -32.177 1.00 148.08 ? 264 CYS A SG 1 ATOM 1834 N N . VAL A 1 238 ? -4.636 -40.131 -31.305 1.00 163.67 ? 265 VAL A N 1 ATOM 1835 C CA . VAL A 1 238 ? -5.726 -41.051 -31.001 1.00 163.09 ? 265 VAL A CA 1 ATOM 1836 C C . VAL A 1 238 ? -6.623 -40.332 -29.988 1.00 157.15 ? 265 VAL A C 1 ATOM 1837 O O . VAL A 1 238 ? -6.141 -39.811 -28.981 1.00 160.44 ? 265 VAL A O 1 ATOM 1838 C CB . VAL A 1 238 ? -5.232 -42.417 -30.491 1.00 164.71 ? 265 VAL A CB 1 ATOM 1839 C CG1 . VAL A 1 238 ? -6.417 -43.277 -30.095 1.00 161.22 ? 265 VAL A CG1 1 ATOM 1840 C CG2 . VAL A 1 238 ? -4.528 -43.148 -31.608 1.00 158.24 ? 265 VAL A CG2 1 ATOM 1841 N N . ALA A 1 239 ? -7.920 -40.295 -30.265 1.00 152.85 ? 266 ALA A N 1 ATOM 1842 C CA . ALA A 1 239 ? -8.909 -39.741 -29.343 1.00 151.49 ? 266 ALA A CA 1 ATOM 1843 C C . ALA A 1 239 ? -9.927 -40.792 -28.918 1.00 150.74 ? 266 ALA A C 1 ATOM 1844 O O . ALA A 1 239 ? -10.216 -41.720 -29.672 1.00 154.54 ? 266 ALA A O 1 ATOM 1845 C CB . ALA A 1 239 ? -9.608 -38.560 -29.976 1.00 144.20 ? 266 ALA A CB 1 ATOM 1846 N N . VAL A 1 240 ? -10.466 -40.650 -27.708 1.00 146.85 ? 267 VAL A N 1 ATOM 1847 C CA . VAL A 1 240 ? -11.525 -41.546 -27.258 1.00 141.08 ? 267 VAL A CA 1 ATOM 1848 C C . VAL A 1 240 ? -12.609 -40.831 -26.441 1.00 137.14 ? 267 VAL A C 1 ATOM 1849 O O . VAL A 1 240 ? -12.465 -39.667 -26.067 1.00 137.55 ? 267 VAL A O 1 ATOM 1850 C CB . VAL A 1 240 ? -10.920 -42.692 -26.396 1.00 136.08 ? 267 VAL A CB 1 ATOM 1851 C CG1 . VAL A 1 240 ? -10.784 -42.257 -24.934 1.00 126.58 ? 267 VAL A CG1 1 ATOM 1852 C CG2 . VAL A 1 240 ? -11.740 -43.972 -26.513 1.00 144.25 ? 267 VAL A CG2 1 ATOM 1853 N N . GLY A 1 241 ? -13.702 -41.547 -26.192 1.00 137.61 ? 268 GLY A N 1 ATOM 1854 C CA . GLY A 1 241 ? -14.856 -41.023 -25.487 1.00 136.20 ? 268 GLY A CA 1 ATOM 1855 C C . GLY A 1 241 ? -16.091 -41.717 -26.035 1.00 140.26 ? 268 GLY A C 1 ATOM 1856 O O . GLY A 1 241 ? -15.978 -42.576 -26.912 1.00 140.59 ? 268 GLY A O 1 ATOM 1857 N N . SER A 1 242 ? -17.266 -41.357 -25.524 1.00 139.12 ? 269 SER A N 1 ATOM 1858 C CA . SER A 1 242 ? -18.525 -41.886 -26.039 1.00 136.26 ? 269 SER A CA 1 ATOM 1859 C C . SER A 1 242 ? -19.503 -40.748 -26.358 1.00 134.71 ? 269 SER A C 1 ATOM 1860 O O . SER A 1 242 ? -19.928 -40.024 -25.459 1.00 135.91 ? 269 SER A O 1 ATOM 1861 C CB . SER A 1 242 ? -19.144 -42.859 -25.028 1.00 130.93 ? 269 SER A CB 1 ATOM 1862 O OG . SER A 1 242 ? -20.391 -43.362 -25.476 1.00 125.53 ? 269 SER A OG 1 ATOM 1863 N N . PRO A 1 243 ? -19.890 -40.609 -27.642 1.00 132.81 ? 270 PRO A N 1 ATOM 1864 C CA . PRO A 1 243 ? -19.436 -41.510 -28.706 1.00 138.37 ? 270 PRO A CA 1 ATOM 1865 C C . PRO A 1 243 ? -18.009 -41.181 -29.121 1.00 139.22 ? 270 PRO A C 1 ATOM 1866 O O . PRO A 1 243 ? -17.505 -40.128 -28.734 1.00 140.69 ? 270 PRO A O 1 ATOM 1867 C CB . PRO A 1 243 ? -20.410 -41.218 -29.848 1.00 136.17 ? 270 PRO A CB 1 ATOM 1868 C CG . PRO A 1 243 ? -20.822 -39.792 -29.633 1.00 135.95 ? 270 PRO A CG 1 ATOM 1869 C CD . PRO A 1 243 ? -20.642 -39.456 -28.172 1.00 130.64 ? 270 PRO A CD 1 ATOM 1870 N N . MET A 1 244 ? -17.366 -42.055 -29.885 1.00 138.68 ? 271 MET A N 1 ATOM 1871 C CA . MET A 1 244 ? -15.957 -41.843 -30.173 1.00 142.93 ? 271 MET A CA 1 ATOM 1872 C C . MET A 1 244 ? -15.865 -40.644 -31.099 1.00 144.00 ? 271 MET A C 1 ATOM 1873 O O . MET A 1 244 ? -16.746 -40.433 -31.932 1.00 145.92 ? 271 MET A O 1 ATOM 1874 C CB . MET A 1 244 ? -15.288 -43.077 -30.790 1.00 152.13 ? 271 MET A CB 1 ATOM 1875 C CG . MET A 1 244 ? -13.761 -43.040 -30.663 1.00 157.55 ? 271 MET A CG 1 ATOM 1876 S SD . MET A 1 244 ? -12.895 -44.612 -30.864 1.00 188.35 ? 271 MET A SD 1 ATOM 1877 C CE . MET A 1 244 ? -12.877 -44.774 -32.644 1.00 167.31 ? 271 MET A CE 1 ATOM 1878 N N . PRO A 1 245 ? -14.804 -39.848 -30.956 1.00 148.89 ? 272 PRO A N 1 ATOM 1879 C CA . PRO A 1 245 ? -14.821 -38.646 -31.788 1.00 149.51 ? 272 PRO A CA 1 ATOM 1880 C C . PRO A 1 245 ? -14.034 -38.907 -33.061 1.00 150.83 ? 272 PRO A C 1 ATOM 1881 O O . PRO A 1 245 ? -13.315 -39.902 -33.156 1.00 148.18 ? 272 PRO A O 1 ATOM 1882 C CB . PRO A 1 245 ? -14.123 -37.590 -30.928 1.00 153.31 ? 272 PRO A CB 1 ATOM 1883 C CG . PRO A 1 245 ? -13.413 -38.338 -29.858 1.00 155.94 ? 272 PRO A CG 1 ATOM 1884 C CD . PRO A 1 245 ? -14.048 -39.672 -29.704 1.00 154.00 ? 272 PRO A CD 1 ATOM 1885 N N . TYR A 1 246 ? -14.175 -38.018 -34.032 1.00 152.78 ? 273 TYR A N 1 ATOM 1886 C CA . TYR A 1 246 ? -13.371 -38.081 -35.241 1.00 162.61 ? 273 TYR A CA 1 ATOM 1887 C C . TYR A 1 246 ? -12.064 -37.359 -34.990 1.00 166.65 ? 273 TYR A C 1 ATOM 1888 O O . TYR A 1 246 ? -11.988 -36.483 -34.129 1.00 162.29 ? 273 TYR A O 1 ATOM 1889 C CB . TYR A 1 246 ? -14.102 -37.473 -36.442 1.00 164.56 ? 273 TYR A CB 1 ATOM 1890 C CG . TYR A 1 246 ? -15.156 -38.377 -37.042 1.00 159.94 ? 273 TYR A CG 1 ATOM 1891 C CD1 . TYR A 1 246 ? -15.855 -39.276 -36.250 1.00 145.80 ? 273 TYR A CD1 1 ATOM 1892 C CD2 . TYR A 1 246 ? -15.450 -38.333 -38.401 1.00 161.74 ? 273 TYR A CD2 1 ATOM 1893 C CE1 . TYR A 1 246 ? -16.817 -40.095 -36.785 1.00 138.48 ? 273 TYR A CE1 1 ATOM 1894 C CE2 . TYR A 1 246 ? -16.424 -39.150 -38.946 1.00 158.18 ? 273 TYR A CE2 1 ATOM 1895 C CZ . TYR A 1 246 ? -17.101 -40.032 -38.132 1.00 145.77 ? 273 TYR A CZ 1 ATOM 1896 O OH . TYR A 1 246 ? -18.071 -40.852 -38.659 1.00 138.47 ? 273 TYR A OH 1 ATOM 1897 N N . VAL A 1 247 ? -11.033 -37.716 -35.748 1.00 168.82 ? 274 VAL A N 1 ATOM 1898 C CA . VAL A 1 247 ? -9.798 -36.961 -35.666 1.00 161.39 ? 274 VAL A CA 1 ATOM 1899 C C . VAL A 1 247 ? -9.314 -36.521 -37.035 1.00 154.48 ? 274 VAL A C 1 ATOM 1900 O O . VAL A 1 247 ? -8.957 -37.312 -37.905 1.00 153.78 ? 274 VAL A O 1 ATOM 1901 C CB . VAL A 1 247 ? -8.664 -37.773 -34.999 1.00 157.10 ? 274 VAL A CB 1 ATOM 1902 C CG1 . VAL A 1 247 ? -7.699 -36.830 -34.290 1.00 164.10 ? 274 VAL A CG1 1 ATOM 1903 C CG2 . VAL A 1 247 ? -9.227 -38.807 -34.035 1.00 156.03 ? 274 VAL A CG2 1 ATOM 1904 N N . LYS A 1 248 ? -9.341 -35.202 -37.169 1.00 151.43 ? 275 LYS A N 1 ATOM 1905 C CA . LYS A 1 248 ? -8.889 -34.458 -38.323 1.00 155.29 ? 275 LYS A CA 1 ATOM 1906 C C . LYS A 1 248 ? -7.642 -33.723 -37.869 1.00 167.68 ? 275 LYS A C 1 ATOM 1907 O O . LYS A 1 248 ? -7.562 -33.282 -36.724 1.00 171.18 ? 275 LYS A O 1 ATOM 1908 C CB . LYS A 1 248 ? -9.949 -33.479 -38.837 1.00 154.60 ? 275 LYS A CB 1 ATOM 1909 C CG . LYS A 1 248 ? -10.295 -32.375 -37.853 1.00 150.58 ? 275 LYS A CG 1 ATOM 1910 C CD . LYS A 1 248 ? -10.939 -31.196 -38.556 1.00 152.12 ? 275 LYS A CD 1 ATOM 1911 C CE . LYS A 1 248 ? -11.288 -30.097 -37.571 1.00 153.06 ? 275 LYS A CE 1 ATOM 1912 N NZ . LYS A 1 248 ? -12.043 -28.990 -38.217 1.00 154.95 ? 275 LYS A NZ 1 ATOM 1913 N N . TRP A 1 249 ? -6.659 -33.610 -38.748 1.00 174.23 ? 276 TRP A N 1 ATOM 1914 C CA . TRP A 1 249 ? -5.460 -32.875 -38.400 1.00 172.19 ? 276 TRP A CA 1 ATOM 1915 C C . TRP A 1 249 ? -5.675 -31.456 -38.921 1.00 174.71 ? 276 TRP A C 1 ATOM 1916 O O . TRP A 1 249 ? -6.489 -31.250 -39.818 1.00 175.24 ? 276 TRP A O 1 ATOM 1917 C CB . TRP A 1 249 ? -4.241 -33.540 -39.040 1.00 165.96 ? 276 TRP A CB 1 ATOM 1918 C CG . TRP A 1 249 ? -3.574 -34.563 -38.163 1.00 161.16 ? 276 TRP A CG 1 ATOM 1919 C CD1 . TRP A 1 249 ? -3.570 -35.912 -38.358 1.00 157.99 ? 276 TRP A CD1 1 ATOM 1920 C CD2 . TRP A 1 249 ? -2.790 -34.328 -36.989 1.00 161.79 ? 276 TRP A CD2 1 ATOM 1921 N NE1 . TRP A 1 249 ? -2.860 -36.537 -37.368 1.00 158.88 ? 276 TRP A NE1 1 ATOM 1922 C CE2 . TRP A 1 249 ? -2.364 -35.587 -36.516 1.00 163.29 ? 276 TRP A CE2 1 ATOM 1923 C CE3 . TRP A 1 249 ? -2.412 -33.182 -36.289 1.00 163.39 ? 276 TRP A CE3 1 ATOM 1924 C CZ2 . TRP A 1 249 ? -1.581 -35.729 -35.379 1.00 167.84 ? 276 TRP A CZ2 1 ATOM 1925 C CZ3 . TRP A 1 249 ? -1.631 -33.324 -35.161 1.00 170.62 ? 276 TRP A CZ3 1 ATOM 1926 C CH2 . TRP A 1 249 ? -1.228 -34.591 -34.714 1.00 173.72 ? 276 TRP A CH2 1 ATOM 1927 N N . MET A 1 250 ? -4.976 -30.476 -38.354 1.00 174.48 ? 277 MET A N 1 ATOM 1928 C CA . MET A 1 250 ? -5.236 -29.077 -38.702 1.00 169.52 ? 277 MET A CA 1 ATOM 1929 C C . MET A 1 250 ? -4.019 -28.171 -38.577 1.00 168.50 ? 277 MET A C 1 ATOM 1930 O O . MET A 1 250 ? -3.281 -28.215 -37.594 1.00 170.25 ? 277 MET A O 1 ATOM 1931 C CB . MET A 1 250 ? -6.363 -28.468 -37.855 1.00 164.99 ? 277 MET A CB 1 ATOM 1932 C CG . MET A 1 250 ? -7.777 -28.805 -38.301 1.00 162.94 ? 277 MET A CG 1 ATOM 1933 S SD . MET A 1 250 ? -8.845 -27.344 -38.266 1.00 178.27 ? 277 MET A SD 1 ATOM 1934 C CE . MET A 1 250 ? -9.103 -27.066 -36.520 1.00 161.94 ? 277 MET A CE 1 ATOM 1935 N N . LEU A 1 251 ? -3.832 -27.344 -39.598 1.00 163.77 ? 278 LEU A N 1 ATOM 1936 C CA . LEU A 1 251 ? -2.807 -26.308 -39.617 1.00 162.93 ? 278 LEU A CA 1 ATOM 1937 C C . LEU A 1 251 ? -3.318 -24.955 -39.107 1.00 164.19 ? 278 LEU A C 1 ATOM 1938 O O . LEU A 1 251 ? -3.216 -23.947 -39.804 1.00 166.15 ? 278 LEU A O 1 ATOM 1939 C CB . LEU A 1 251 ? -2.239 -26.161 -41.030 1.00 162.17 ? 278 LEU A CB 1 ATOM 1940 C CG . LEU A 1 251 ? -1.174 -27.216 -41.327 1.00 154.15 ? 278 LEU A CG 1 ATOM 1941 C CD1 . LEU A 1 251 ? -0.610 -27.046 -42.724 1.00 148.59 ? 278 LEU A CD1 1 ATOM 1942 C CD2 . LEU A 1 251 ? -0.072 -27.131 -40.285 1.00 161.58 ? 278 LEU A CD2 1 ATOM 1943 N N . GLY A 1 252 ? -3.865 -24.941 -37.894 1.00 167.43 ? 279 GLY A N 1 ATOM 1944 C CA . GLY A 1 252 ? -4.440 -23.734 -37.323 1.00 171.79 ? 279 GLY A CA 1 ATOM 1945 C C . GLY A 1 252 ? -5.877 -23.476 -37.728 1.00 173.55 ? 279 GLY A C 1 ATOM 1946 O O . GLY A 1 252 ? -6.797 -23.689 -36.931 1.00 178.02 ? 279 GLY A O 1 ATOM 1947 N N . ALA A 1 253 ? -6.088 -22.972 -38.936 1.00 163.72 ? 280 ALA A N 1 ATOM 1948 C CA . ALA A 1 253 ? -7.442 -22.677 -39.372 1.00 162.05 ? 280 ALA A CA 1 ATOM 1949 C C . ALA A 1 253 ? -7.892 -23.767 -40.335 1.00 176.23 ? 280 ALA A C 1 ATOM 1950 O O . ALA A 1 253 ? -8.821 -24.521 -40.035 1.00 185.87 ? 280 ALA A O 1 ATOM 1951 C CB . ALA A 1 253 ? -7.511 -21.306 -40.032 1.00 146.57 ? 280 ALA A CB 1 ATOM 1952 N N . GLU A 1 254 ? -7.240 -23.849 -41.488 1.00 176.20 ? 281 GLU A N 1 ATOM 1953 C CA . GLU A 1 254 ? -7.564 -24.876 -42.464 1.00 175.76 ? 281 GLU A CA 1 ATOM 1954 C C . GLU A 1 254 ? -7.470 -26.307 -41.912 1.00 174.87 ? 281 GLU A C 1 ATOM 1955 O O . GLU A 1 254 ? -6.608 -26.620 -41.087 1.00 169.85 ? 281 GLU A O 1 ATOM 1956 C CB . GLU A 1 254 ? -6.647 -24.711 -43.692 1.00 172.53 ? 281 GLU A CB 1 ATOM 1957 C CG . GLU A 1 254 ? -6.519 -25.927 -44.596 1.00 175.46 ? 281 GLU A CG 1 ATOM 1958 C CD . GLU A 1 254 ? -5.353 -26.820 -44.209 1.00 170.98 ? 281 GLU A CD 1 ATOM 1959 O OE1 . GLU A 1 254 ? -4.638 -26.482 -43.240 1.00 165.52 ? 281 GLU A OE1 1 ATOM 1960 O OE2 . GLU A 1 254 ? -5.155 -27.857 -44.874 1.00 176.08 ? 281 GLU A OE2 1 ATOM 1961 N N . ASP A 1 255 ? -8.380 -27.155 -42.384 1.00 177.18 ? 282 ASP A N 1 ATOM 1962 C CA . ASP A 1 255 ? -8.529 -28.559 -41.988 1.00 172.22 ? 282 ASP A CA 1 ATOM 1963 C C . ASP A 1 255 ? -7.632 -29.348 -42.942 1.00 168.81 ? 282 ASP A C 1 ATOM 1964 O O . ASP A 1 255 ? -7.582 -29.037 -44.129 1.00 166.98 ? 282 ASP A O 1 ATOM 1965 C CB . ASP A 1 255 ? -9.988 -29.039 -42.000 1.00 163.35 ? 282 ASP A CB 1 ATOM 1966 C CG . ASP A 1 255 ? -10.686 -28.774 -43.305 1.00 162.53 ? 282 ASP A CG 1 ATOM 1967 O OD1 . ASP A 1 255 ? -10.265 -27.852 -44.029 1.00 178.18 ? 282 ASP A OD1 1 ATOM 1968 O OD2 . ASP A 1 255 ? -11.673 -29.486 -43.598 1.00 150.47 ? 282 ASP A OD2 1 ATOM 1969 N N . LEU A 1 256 ? -6.933 -30.361 -42.446 1.00 168.48 ? 283 LEU A N 1 ATOM 1970 C CA . LEU A 1 256 ? -6.000 -31.119 -43.284 1.00 168.60 ? 283 LEU A CA 1 ATOM 1971 C C . LEU A 1 256 ? -6.581 -32.422 -43.807 1.00 173.70 ? 283 LEU A C 1 ATOM 1972 O O . LEU A 1 256 ? -6.214 -32.868 -44.894 1.00 175.55 ? 283 LEU A O 1 ATOM 1973 C CB . LEU A 1 256 ? -4.735 -31.442 -42.482 1.00 166.27 ? 283 LEU A CB 1 ATOM 1974 C CG . LEU A 1 256 ? -3.754 -30.356 -42.039 1.00 165.93 ? 283 LEU A CG 1 ATOM 1975 C CD1 . LEU A 1 256 ? -2.613 -30.980 -41.261 1.00 156.46 ? 283 LEU A CD1 1 ATOM 1976 C CD2 . LEU A 1 256 ? -3.182 -29.666 -43.263 1.00 176.07 ? 283 LEU A CD2 1 ATOM 1977 N N . THR A 1 257 ? -7.490 -33.036 -43.065 1.00 176.03 ? 284 THR A N 1 ATOM 1978 C CA . THR A 1 257 ? -8.236 -34.140 -43.651 1.00 174.41 ? 284 THR A CA 1 ATOM 1979 C C . THR A 1 257 ? -9.529 -33.634 -44.290 1.00 177.43 ? 284 THR A C 1 ATOM 1980 O O . THR A 1 257 ? -10.298 -32.907 -43.659 1.00 173.37 ? 284 THR A O 1 ATOM 1981 C CB . THR A 1 257 ? -8.565 -35.229 -42.613 1.00 163.44 ? 284 THR A CB 1 ATOM 1982 O OG1 . THR A 1 257 ? -7.857 -34.968 -41.397 1.00 166.61 ? 284 THR A OG1 1 ATOM 1983 C CG2 . THR A 1 257 ? -8.176 -36.612 -43.141 1.00 144.46 ? 284 THR A CG2 1 ATOM 1984 N N . PRO A 1 258 ? -9.770 -34.034 -45.551 1.00 178.95 ? 285 PRO A N 1 ATOM 1985 C CA . PRO A 1 258 ? -10.881 -33.600 -46.405 1.00 175.01 ? 285 PRO A CA 1 ATOM 1986 C C . PRO A 1 258 ? -12.222 -34.106 -45.890 1.00 171.45 ? 285 PRO A C 1 ATOM 1987 O O . PRO A 1 258 ? -12.347 -35.278 -45.538 1.00 168.81 ? 285 PRO A O 1 ATOM 1988 C CB . PRO A 1 258 ? -10.544 -34.215 -47.766 1.00 166.89 ? 285 PRO A CB 1 ATOM 1989 C CG . PRO A 1 258 ? -9.748 -35.417 -47.432 1.00 167.03 ? 285 PRO A CG 1 ATOM 1990 C CD . PRO A 1 258 ? -8.905 -34.998 -46.256 1.00 170.98 ? 285 PRO A CD 1 ATOM 1991 N N . GLU A 1 259 ? -13.202 -33.212 -45.837 1.00 168.90 ? 286 GLU A N 1 ATOM 1992 C CA . GLU A 1 259 ? -14.442 -33.415 -45.101 1.00 158.33 ? 286 GLU A CA 1 ATOM 1993 C C . GLU A 1 259 ? -15.167 -34.650 -45.614 1.00 156.37 ? 286 GLU A C 1 ATOM 1994 O O . GLU A 1 259 ? -15.646 -35.457 -44.814 1.00 152.83 ? 286 GLU A O 1 ATOM 1995 C CB . GLU A 1 259 ? -15.342 -32.182 -45.174 1.00 149.36 ? 286 GLU A CB 1 ATOM 1996 C CG . GLU A 1 259 ? -14.833 -31.029 -44.328 1.00 144.14 ? 286 GLU A CG 1 ATOM 1997 C CD . GLU A 1 259 ? -15.946 -30.123 -43.845 1.00 142.95 ? 286 GLU A CD 1 ATOM 1998 O OE1 . GLU A 1 259 ? -17.116 -30.561 -43.862 1.00 141.08 ? 286 GLU A OE1 1 ATOM 1999 O OE2 . GLU A 1 259 ? -15.651 -28.974 -43.451 1.00 147.03 ? 286 GLU A OE2 1 ATOM 2000 N N . ASP A 1 260 ? -15.268 -34.803 -46.932 1.00 160.65 ? 287 ASP A N 1 ATOM 2001 C CA . ASP A 1 260 ? -16.038 -35.908 -47.488 1.00 153.19 ? 287 ASP A CA 1 ATOM 2002 C C . ASP A 1 260 ? -15.432 -37.272 -47.119 1.00 150.63 ? 287 ASP A C 1 ATOM 2003 O O . ASP A 1 260 ? -16.001 -38.313 -47.445 1.00 145.90 ? 287 ASP A O 1 ATOM 2004 C CB . ASP A 1 260 ? -16.073 -35.795 -49.021 1.00 153.18 ? 287 ASP A CB 1 ATOM 2005 C CG . ASP A 1 260 ? -16.702 -34.503 -49.512 1.00 149.25 ? 287 ASP A CG 1 ATOM 2006 O OD1 . ASP A 1 260 ? -16.931 -33.593 -48.690 1.00 155.65 ? 287 ASP A OD1 1 ATOM 2007 O OD2 . ASP A 1 260 ? -16.932 -34.385 -50.736 1.00 142.52 ? 287 ASP A OD2 1 ATOM 2008 N N . ASP A 1 261 ? -14.272 -37.263 -46.460 1.00 154.38 ? 288 ASP A N 1 ATOM 2009 C CA . ASP A 1 261 ? -13.661 -38.489 -45.931 1.00 157.35 ? 288 ASP A CA 1 ATOM 2010 C C . ASP A 1 261 ? -12.805 -38.240 -44.679 1.00 160.00 ? 288 ASP A C 1 ATOM 2011 O O . ASP A 1 261 ? -11.642 -37.862 -44.805 1.00 165.23 ? 288 ASP A O 1 ATOM 2012 C CB . ASP A 1 261 ? -12.816 -39.189 -46.997 1.00 160.55 ? 288 ASP A CB 1 ATOM 2013 C CG . ASP A 1 261 ? -12.535 -40.652 -46.655 1.00 156.10 ? 288 ASP A CG 1 ATOM 2014 O OD1 . ASP A 1 261 ? -12.686 -41.039 -45.477 1.00 141.91 ? 288 ASP A OD1 1 ATOM 2015 O OD2 . ASP A 1 261 ? -12.170 -41.421 -47.571 1.00 158.93 ? 288 ASP A OD2 1 ATOM 2016 N N . MET A 1 262 ? -13.346 -38.467 -43.485 1.00 156.14 ? 289 MET A N 1 ATOM 2017 C CA . MET A 1 262 ? -12.661 -38.024 -42.267 1.00 152.84 ? 289 MET A CA 1 ATOM 2018 C C . MET A 1 262 ? -12.597 -39.193 -41.291 1.00 146.97 ? 289 MET A C 1 ATOM 2019 O O . MET A 1 262 ? -13.632 -39.681 -40.840 1.00 140.32 ? 289 MET A O 1 ATOM 2020 C CB . MET A 1 262 ? -13.370 -36.822 -41.642 1.00 149.27 ? 289 MET A CB 1 ATOM 2021 C CG . MET A 1 262 ? -12.778 -36.360 -40.318 1.00 148.12 ? 289 MET A CG 1 ATOM 2022 S SD . MET A 1 262 ? -13.485 -34.800 -39.746 1.00 154.71 ? 289 MET A SD 1 ATOM 2023 C CE . MET A 1 262 ? -13.135 -33.740 -41.148 1.00 160.29 ? 289 MET A CE 1 ATOM 2024 N N . PRO A 1 263 ? -11.371 -39.648 -40.965 1.00 157.15 ? 290 PRO A N 1 ATOM 2025 C CA . PRO A 1 263 ? -11.253 -40.917 -40.229 1.00 152.51 ? 290 PRO A CA 1 ATOM 2026 C C . PRO A 1 263 ? -11.798 -40.877 -38.803 1.00 149.35 ? 290 PRO A C 1 ATOM 2027 O O . PRO A 1 263 ? -12.068 -39.800 -38.268 1.00 154.25 ? 290 PRO A O 1 ATOM 2028 C CB . PRO A 1 263 ? -9.743 -41.169 -40.222 1.00 161.99 ? 290 PRO A CB 1 ATOM 2029 C CG . PRO A 1 263 ? -9.127 -39.808 -40.372 1.00 172.08 ? 290 PRO A CG 1 ATOM 2030 C CD . PRO A 1 263 ? -10.063 -39.031 -41.247 1.00 167.72 ? 290 PRO A CD 1 ATOM 2031 N N . ILE A 1 264 ? -11.956 -42.051 -38.198 1.00 142.87 ? 291 ILE A N 1 ATOM 2032 C CA . ILE A 1 264 ? -12.523 -42.135 -36.858 1.00 145.71 ? 291 ILE A CA 1 ATOM 2033 C C . ILE A 1 264 ? -11.586 -42.572 -35.727 1.00 149.81 ? 291 ILE A C 1 ATOM 2034 O O . ILE A 1 264 ? -11.164 -43.726 -35.686 1.00 152.19 ? 291 ILE A O 1 ATOM 2035 C CB . ILE A 1 264 ? -13.718 -43.093 -36.898 1.00 142.95 ? 291 ILE A CB 1 ATOM 2036 C CG1 . ILE A 1 264 ? -14.722 -42.596 -37.936 1.00 156.43 ? 291 ILE A CG1 1 ATOM 2037 C CG2 . ILE A 1 264 ? -14.321 -43.283 -35.511 1.00 136.11 ? 291 ILE A CG2 1 ATOM 2038 C CD1 . ILE A 1 264 ? -15.955 -43.405 -38.011 1.00 149.96 ? 291 ILE A CD1 1 ATOM 2039 N N . GLY A 1 265 ? -11.245 -41.663 -34.822 1.00 152.29 ? 292 GLY A N 1 ATOM 2040 C CA . GLY A 1 265 ? -10.490 -42.022 -33.630 1.00 153.44 ? 292 GLY A CA 1 ATOM 2041 C C . GLY A 1 265 ? -8.986 -42.194 -33.716 1.00 156.01 ? 292 GLY A C 1 ATOM 2042 O O . GLY A 1 265 ? -8.283 -42.028 -32.718 1.00 152.75 ? 292 GLY A O 1 ATOM 2043 N N . ARG A 1 266 ? -8.487 -42.532 -34.901 1.00 160.91 ? 293 ARG A N 1 ATOM 2044 C CA . ARG A 1 266 ? -7.071 -42.878 -35.053 1.00 153.18 ? 293 ARG A CA 1 ATOM 2045 C C . ARG A 1 266 ? -6.457 -42.405 -36.364 1.00 150.93 ? 293 ARG A C 1 ATOM 2046 O O . ARG A 1 266 ? -6.420 -43.152 -37.340 1.00 149.59 ? 293 ARG A O 1 ATOM 2047 C CB . ARG A 1 266 ? -6.855 -44.387 -34.912 1.00 145.16 ? 293 ARG A CB 1 ATOM 2048 C CG . ARG A 1 266 ? -5.409 -44.696 -34.569 1.00 138.78 ? 293 ARG A CG 1 ATOM 2049 C CD . ARG A 1 266 ? -5.091 -46.164 -34.447 1.00 135.10 ? 293 ARG A CD 1 ATOM 2050 N NE . ARG A 1 266 ? -3.674 -46.327 -34.133 1.00 139.75 ? 293 ARG A NE 1 ATOM 2051 C CZ . ARG A 1 266 ? -3.122 -47.450 -33.689 1.00 146.24 ? 293 ARG A CZ 1 ATOM 2052 N NH1 . ARG A 1 266 ? -3.867 -48.528 -33.498 1.00 142.49 ? 293 ARG A NH1 1 ATOM 2053 N NH2 . ARG A 1 266 ? -1.823 -47.487 -33.429 1.00 156.94 ? 293 ARG A NH2 1 ATOM 2054 N N . ASN A 1 267 ? -5.962 -41.176 -36.383 1.00 145.24 ? 294 ASN A N 1 ATOM 2055 C CA . ASN A 1 267 ? -5.297 -40.665 -37.572 1.00 149.77 ? 294 ASN A CA 1 ATOM 2056 C C . ASN A 1 267 ? -3.796 -40.463 -37.324 1.00 157.60 ? 294 ASN A C 1 ATOM 2057 O O . ASN A 1 267 ? -3.401 -39.759 -36.394 1.00 158.88 ? 294 ASN A O 1 ATOM 2058 C CB . ASN A 1 267 ? -5.960 -39.368 -38.045 1.00 148.57 ? 294 ASN A CB 1 ATOM 2059 C CG . ASN A 1 267 ? -5.316 -38.804 -39.295 1.00 153.78 ? 294 ASN A CG 1 ATOM 2060 O OD1 . ASN A 1 267 ? -4.596 -39.502 -40.008 1.00 148.59 ? 294 ASN A OD1 1 ATOM 2061 N ND2 . ASN A 1 267 ? -5.619 -37.548 -39.598 1.00 161.05 ? 294 ASN A ND2 1 ATOM 2062 N N . VAL A 1 268 ? -2.967 -41.097 -38.153 1.00 158.64 ? 295 VAL A N 1 ATOM 2063 C CA . VAL A 1 268 ? -1.516 -41.009 -38.005 1.00 155.60 ? 295 VAL A CA 1 ATOM 2064 C C . VAL A 1 268 ? -0.901 -40.281 -39.208 1.00 160.03 ? 295 VAL A C 1 ATOM 2065 O O . VAL A 1 268 ? -1.074 -40.675 -40.362 1.00 161.51 ? 295 VAL A O 1 ATOM 2066 C CB . VAL A 1 268 ? -0.876 -42.426 -37.841 1.00 139.04 ? 295 VAL A CB 1 ATOM 2067 C CG1 . VAL A 1 268 ? -1.341 -43.073 -36.549 1.00 137.65 ? 295 VAL A CG1 1 ATOM 2068 C CG2 . VAL A 1 268 ? -1.217 -43.335 -39.015 1.00 123.76 ? 295 VAL A CG2 1 ATOM 2069 N N . LEU A 1 269 ? -0.215 -39.178 -38.916 1.00 160.26 ? 296 LEU A N 1 ATOM 2070 C CA . LEU A 1 269 ? 0.309 -38.262 -39.937 1.00 157.52 ? 296 LEU A CA 1 ATOM 2071 C C . LEU A 1 269 ? 1.704 -38.591 -40.485 1.00 171.45 ? 296 LEU A C 1 ATOM 2072 O O . LEU A 1 269 ? 2.674 -38.652 -39.730 1.00 179.59 ? 296 LEU A O 1 ATOM 2073 C CB . LEU A 1 269 ? 0.313 -36.836 -39.379 1.00 151.57 ? 296 LEU A CB 1 ATOM 2074 C CG . LEU A 1 269 ? -0.198 -35.763 -40.343 1.00 152.67 ? 296 LEU A CG 1 ATOM 2075 C CD1 . LEU A 1 269 ? -1.458 -36.239 -41.054 1.00 152.12 ? 296 LEU A CD1 1 ATOM 2076 C CD2 . LEU A 1 269 ? -0.456 -34.453 -39.615 1.00 162.79 ? 296 LEU A CD2 1 ATOM 2077 N N . GLU A 1 270 ? 1.789 -38.805 -41.798 1.00 176.82 ? 297 GLU A N 1 ATOM 2078 C CA . GLU A 1 270 ? 3.061 -39.051 -42.485 1.00 185.08 ? 297 GLU A CA 1 ATOM 2079 C C . GLU A 1 270 ? 3.633 -37.776 -43.143 1.00 185.74 ? 297 GLU A C 1 ATOM 2080 O O . GLU A 1 270 ? 3.052 -37.249 -44.094 1.00 183.95 ? 297 GLU A O 1 ATOM 2081 C CB . GLU A 1 270 ? 2.877 -40.157 -43.530 1.00 180.16 ? 297 GLU A CB 1 ATOM 2082 C CG . GLU A 1 270 ? 3.092 -41.561 -42.978 1.00 172.60 ? 297 GLU A CG 1 ATOM 2083 C CD . GLU A 1 270 ? 1.971 -42.530 -43.303 1.00 175.86 ? 297 GLU A CD 1 ATOM 2084 O OE1 . GLU A 1 270 ? 0.808 -42.247 -42.945 1.00 178.99 ? 297 GLU A OE1 1 ATOM 2085 O OE2 . GLU A 1 270 ? 2.260 -43.583 -43.909 1.00 184.14 ? 297 GLU A OE2 1 ATOM 2086 N N . LEU A 1 271 ? 4.772 -37.294 -42.636 1.00 185.54 ? 298 LEU A N 1 ATOM 2087 C CA . LEU A 1 271 ? 5.439 -36.081 -43.150 1.00 189.32 ? 298 LEU A CA 1 ATOM 2088 C C . LEU A 1 271 ? 6.642 -36.295 -44.089 1.00 200.09 ? 298 LEU A C 1 ATOM 2089 O O . LEU A 1 271 ? 7.481 -37.173 -43.864 1.00 198.72 ? 298 LEU A O 1 ATOM 2090 C CB . LEU A 1 271 ? 5.855 -35.193 -41.980 1.00 187.07 ? 298 LEU A CB 1 ATOM 2091 C CG . LEU A 1 271 ? 4.631 -34.567 -41.302 1.00 177.32 ? 298 LEU A CG 1 ATOM 2092 C CD1 . LEU A 1 271 ? 4.962 -33.985 -39.938 1.00 181.62 ? 298 LEU A CD1 1 ATOM 2093 C CD2 . LEU A 1 271 ? 4.008 -33.517 -42.210 1.00 169.39 ? 298 LEU A CD2 1 ATOM 2094 N N . ASN A 1 272 ? 6.708 -35.483 -45.149 1.00 211.68 ? 299 ASN A N 1 ATOM 2095 C CA . ASN A 1 272 ? 7.802 -35.527 -46.139 1.00 212.27 ? 299 ASN A CA 1 ATOM 2096 C C . ASN A 1 272 ? 8.991 -34.539 -46.143 1.00 205.13 ? 299 ASN A C 1 ATOM 2097 O O . ASN A 1 272 ? 10.111 -34.904 -45.806 1.00 195.61 ? 299 ASN A O 1 ATOM 2098 C CB . ASN A 1 272 ? 7.176 -35.429 -47.532 1.00 207.37 ? 299 ASN A CB 1 ATOM 2099 C CG . ASN A 1 272 ? 6.590 -36.740 -47.995 1.00 194.61 ? 299 ASN A CG 1 ATOM 2100 O OD1 . ASN A 1 272 ? 6.584 -37.725 -47.256 1.00 187.33 ? 299 ASN A OD1 1 ATOM 2101 N ND2 . ASN A 1 272 ? 6.110 -36.768 -49.231 1.00 195.44 ? 299 ASN A ND2 1 ATOM 2102 N N . ASP A 1 273 ? 8.737 -33.306 -46.581 1.00 204.10 ? 300 ASP A N 1 ATOM 2103 C CA . ASP A 1 273 ? 9.761 -32.252 -46.662 1.00 194.16 ? 300 ASP A CA 1 ATOM 2104 C C . ASP A 1 273 ? 9.650 -30.980 -45.815 1.00 189.00 ? 300 ASP A C 1 ATOM 2105 O O . ASP A 1 273 ? 9.309 -29.933 -46.366 1.00 186.65 ? 300 ASP A O 1 ATOM 2106 C CB . ASP A 1 273 ? 9.902 -31.802 -48.131 1.00 197.27 ? 300 ASP A CB 1 ATOM 2107 C CG . ASP A 1 273 ? 11.128 -30.904 -48.358 1.00 200.71 ? 300 ASP A CG 1 ATOM 2108 O OD1 . ASP A 1 273 ? 12.248 -31.439 -48.490 1.00 203.40 ? 300 ASP A OD1 1 ATOM 2109 O OD2 . ASP A 1 273 ? 10.963 -29.666 -48.417 1.00 199.31 ? 300 ASP A OD2 1 ATOM 2110 N N . VAL A 1 274 ? 9.778 -31.038 -44.488 1.00 183.79 ? 301 VAL A N 1 ATOM 2111 C CA . VAL A 1 274 ? 9.722 -29.751 -43.801 1.00 173.95 ? 301 VAL A CA 1 ATOM 2112 C C . VAL A 1 274 ? 10.995 -28.982 -44.204 1.00 175.49 ? 301 VAL A C 1 ATOM 2113 O O . VAL A 1 274 ? 12.098 -29.432 -44.048 1.00 180.72 ? 301 VAL A O 1 ATOM 2114 C CB . VAL A 1 274 ? 9.694 -29.911 -42.261 1.00 163.11 ? 301 VAL A CB 1 ATOM 2115 C CG1 . VAL A 1 274 ? 9.804 -28.564 -41.577 1.00 161.69 ? 301 VAL A CG1 1 ATOM 2116 C CG2 . VAL A 1 274 ? 8.459 -30.671 -41.806 1.00 164.73 ? 301 VAL A CG2 1 ATOM 2117 N N . ARG A 1 275 ? 10.772 -27.795 -44.729 1.00 172.32 ? 302 ARG A N 1 ATOM 2118 C CA . ARG A 1 275 ? 11.753 -26.820 -45.205 1.00 168.08 ? 302 ARG A CA 1 ATOM 2119 C C . ARG A 1 275 ? 11.552 -25.851 -44.100 1.00 169.07 ? 302 ARG A C 1 ATOM 2120 O O . ARG A 1 275 ? 12.457 -25.644 -43.277 1.00 171.47 ? 302 ARG A O 1 ATOM 2121 C CB . ARG A 1 275 ? 11.557 -26.359 -46.652 1.00 156.53 ? 302 ARG A CB 1 ATOM 2122 C CG . ARG A 1 275 ? 12.610 -25.371 -47.157 1.00 150.35 ? 302 ARG A CG 1 ATOM 2123 C CD . ARG A 1 275 ? 12.024 -24.172 -47.780 1.00 139.35 ? 302 ARG A CD 1 ATOM 2124 N NE . ARG A 1 275 ? 11.364 -24.522 -49.039 1.00 127.97 ? 302 ARG A NE 1 ATOM 2125 C CZ . ARG A 1 275 ? 10.056 -24.420 -49.250 1.00 127.83 ? 302 ARG A CZ 1 ATOM 2126 N NH1 . ARG A 1 275 ? 9.265 -23.960 -48.290 1.00 135.25 ? 302 ARG A NH1 1 ATOM 2127 N NH2 . ARG A 1 275 ? 9.543 -24.760 -50.422 1.00 122.46 ? 302 ARG A NH2 1 ATOM 2128 N N . GLN A 1 276 ? 10.480 -25.075 -44.185 1.00 163.84 ? 303 GLN A N 1 ATOM 2129 C CA . GLN A 1 276 ? 10.102 -24.081 -43.196 1.00 159.93 ? 303 GLN A CA 1 ATOM 2130 C C . GLN A 1 276 ? 9.417 -24.726 -41.955 1.00 166.31 ? 303 GLN A C 1 ATOM 2131 O O . GLN A 1 276 ? 8.743 -25.788 -42.049 1.00 169.82 ? 303 GLN A O 1 ATOM 2132 C CB . GLN A 1 276 ? 9.208 -23.067 -43.834 1.00 152.43 ? 303 GLN A CB 1 ATOM 2133 C CG . GLN A 1 276 ? 9.774 -22.525 -45.062 1.00 142.47 ? 303 GLN A CG 1 ATOM 2134 C CD . GLN A 1 276 ? 8.858 -21.702 -45.884 1.00 136.58 ? 303 GLN A CD 1 ATOM 2135 O OE1 . GLN A 1 276 ? 7.843 -22.192 -46.403 1.00 130.90 ? 303 GLN A OE1 1 ATOM 2136 N NE2 . GLN A 1 276 ? 9.168 -20.431 -45.981 1.00 140.58 ? 303 GLN A NE2 1 ATOM 2137 N N . SER A 1 277 ? 9.490 -24.096 -40.790 1.00 165.60 ? 304 SER A N 1 ATOM 2138 C CA . SER A 1 277 ? 8.733 -24.473 -39.555 1.00 170.03 ? 304 SER A CA 1 ATOM 2139 C C . SER A 1 277 ? 7.219 -24.301 -39.614 1.00 170.92 ? 304 SER A C 1 ATOM 2140 O O . SER A 1 277 ? 6.731 -23.497 -40.399 1.00 166.74 ? 304 SER A O 1 ATOM 2141 C CB . SER A 1 277 ? 9.280 -23.675 -38.350 1.00 177.05 ? 304 SER A CB 1 ATOM 2142 O OG . SER A 1 277 ? 10.661 -23.917 -38.145 1.00 183.77 ? 304 SER A OG 1 ATOM 2143 N N . ALA A 1 278 ? 6.477 -25.068 -38.814 1.00 181.20 ? 305 ALA A N 1 ATOM 2144 C CA . ALA A 1 278 ? 5.010 -24.951 -38.801 1.00 182.97 ? 305 ALA A CA 1 ATOM 2145 C C . ALA A 1 278 ? 4.400 -25.433 -37.474 1.00 189.09 ? 305 ALA A C 1 ATOM 2146 O O . ALA A 1 278 ? 5.085 -26.026 -36.640 1.00 185.11 ? 305 ALA A O 1 ATOM 2147 C CB . ALA A 1 278 ? 4.405 -25.743 -39.969 1.00 163.53 ? 305 ALA A CB 1 ATOM 2148 N N . ASN A 1 279 ? 3.107 -25.153 -37.300 1.00 191.28 ? 306 ASN A N 1 ATOM 2149 C CA . ASN A 1 279 ? 2.277 -25.595 -36.167 1.00 187.67 ? 306 ASN A CA 1 ATOM 2150 C C . ASN A 1 279 ? 1.109 -26.553 -36.471 1.00 187.01 ? 306 ASN A C 1 ATOM 2151 O O . ASN A 1 279 ? 0.176 -26.163 -37.172 1.00 178.38 ? 306 ASN A O 1 ATOM 2152 C CB . ASN A 1 279 ? 1.756 -24.348 -35.443 1.00 182.13 ? 306 ASN A CB 1 ATOM 2153 C CG . ASN A 1 279 ? 2.659 -23.925 -34.297 1.00 176.87 ? 306 ASN A CG 1 ATOM 2154 O OD1 . ASN A 1 279 ? 3.756 -24.457 -34.129 1.00 170.40 ? 306 ASN A OD1 1 ATOM 2155 N ND2 . ASN A 1 279 ? 2.208 -22.953 -33.512 1.00 179.87 ? 306 ASN A ND2 1 ATOM 2156 N N . TYR A 1 280 ? 1.141 -27.788 -35.961 1.00 187.51 ? 307 TYR A N 1 ATOM 2157 C CA . TYR A 1 280 ? 0.076 -28.753 -36.285 1.00 176.86 ? 307 TYR A CA 1 ATOM 2158 C C . TYR A 1 280 ? -0.932 -29.074 -35.169 1.00 174.01 ? 307 TYR A C 1 ATOM 2159 O O . TYR A 1 280 ? -0.562 -29.570 -34.106 1.00 175.11 ? 307 TYR A O 1 ATOM 2160 C CB . TYR A 1 280 ? 0.715 -30.086 -36.683 1.00 170.78 ? 307 TYR A CB 1 ATOM 2161 C CG . TYR A 1 280 ? 1.252 -30.167 -38.085 1.00 174.54 ? 307 TYR A CG 1 ATOM 2162 C CD1 . TYR A 1 280 ? 2.607 -29.998 -38.334 1.00 176.21 ? 307 TYR A CD1 1 ATOM 2163 C CD2 . TYR A 1 280 ? 0.416 -30.448 -39.155 1.00 170.82 ? 307 TYR A CD2 1 ATOM 2164 C CE1 . TYR A 1 280 ? 3.112 -30.083 -39.613 1.00 176.61 ? 307 TYR A CE1 1 ATOM 2165 C CE2 . TYR A 1 280 ? 0.909 -30.536 -40.439 1.00 167.80 ? 307 TYR A CE2 1 ATOM 2166 C CZ . TYR A 1 280 ? 2.260 -30.352 -40.662 1.00 175.96 ? 307 TYR A CZ 1 ATOM 2167 O OH . TYR A 1 280 ? 2.758 -30.438 -41.941 1.00 184.44 ? 307 TYR A OH 1 ATOM 2168 N N . THR A 1 281 ? -2.209 -28.792 -35.438 1.00 173.96 ? 308 THR A N 1 ATOM 2169 C CA . THR A 1 281 ? -3.315 -29.041 -34.502 1.00 177.89 ? 308 THR A CA 1 ATOM 2170 C C . THR A 1 281 ? -4.030 -30.372 -34.756 1.00 174.91 ? 308 THR A C 1 ATOM 2171 O O . THR A 1 281 ? -4.219 -30.766 -35.908 1.00 167.74 ? 308 THR A O 1 ATOM 2172 C CB . THR A 1 281 ? -4.374 -27.911 -34.559 1.00 171.19 ? 308 THR A CB 1 ATOM 2173 O OG1 . THR A 1 281 ? -3.767 -26.707 -35.044 1.00 167.54 ? 308 THR A OG1 1 ATOM 2174 C CG2 . THR A 1 281 ? -4.957 -27.641 -33.179 1.00 165.12 ? 308 THR A CG2 1 ATOM 2175 N N . CYS A 1 282 ? -4.431 -31.064 -33.692 1.00 176.43 ? 309 CYS A N 1 ATOM 2176 C CA . CYS A 1 282 ? -5.170 -32.315 -33.846 1.00 165.31 ? 309 CYS A CA 1 ATOM 2177 C C . CYS A 1 282 ? -6.507 -32.166 -33.120 1.00 161.64 ? 309 CYS A C 1 ATOM 2178 O O . CYS A 1 282 ? -6.552 -32.121 -31.890 1.00 153.62 ? 309 CYS A O 1 ATOM 2179 C CB . CYS A 1 282 ? -4.371 -33.501 -33.303 1.00 161.59 ? 309 CYS A CB 1 ATOM 2180 S SG . CYS A 1 282 ? -5.349 -34.859 -32.644 1.00 152.40 ? 309 CYS A SG 1 ATOM 2181 N N . VAL A 1 283 ? -7.591 -32.070 -33.879 1.00 164.75 ? 310 VAL A N 1 ATOM 2182 C CA . VAL A 1 283 ? -8.915 -31.914 -33.285 1.00 158.75 ? 310 VAL A CA 1 ATOM 2183 C C . VAL A 1 283 ? -9.722 -33.198 -33.161 1.00 156.34 ? 310 VAL A C 1 ATOM 2184 O O . VAL A 1 283 ? -9.753 -34.024 -34.075 1.00 153.54 ? 310 VAL A O 1 ATOM 2185 C CB . VAL A 1 283 ? -9.742 -30.892 -34.083 1.00 156.85 ? 310 VAL A CB 1 ATOM 2186 C CG1 . VAL A 1 283 ? -11.010 -30.500 -33.328 1.00 155.61 ? 310 VAL A CG1 1 ATOM 2187 C CG2 . VAL A 1 283 ? -8.895 -29.681 -34.364 1.00 159.25 ? 310 VAL A CG2 1 ATOM 2188 N N . ALA A 1 284 ? -10.384 -33.351 -32.020 1.00 158.16 ? 311 ALA A N 1 ATOM 2189 C CA . ALA A 1 284 ? -11.294 -34.461 -31.814 1.00 154.89 ? 311 ALA A CA 1 ATOM 2190 C C . ALA A 1 284 ? -12.630 -33.849 -31.434 1.00 156.40 ? 311 ALA A C 1 ATOM 2191 O O . ALA A 1 284 ? -12.682 -32.939 -30.605 1.00 147.71 ? 311 ALA A O 1 ATOM 2192 C CB . ALA A 1 284 ? -10.792 -35.387 -30.733 1.00 146.54 ? 311 ALA A CB 1 ATOM 2193 N N . MET A 1 285 ? -13.714 -34.341 -32.023 1.00 160.74 ? 312 MET A N 1 ATOM 2194 C CA . MET A 1 285 ? -15.019 -33.826 -31.654 1.00 154.85 ? 312 MET A CA 1 ATOM 2195 C C . MET A 1 285 ? -16.066 -34.921 -31.541 1.00 147.46 ? 312 MET A C 1 ATOM 2196 O O . MET A 1 285 ? -16.329 -35.642 -32.508 1.00 139.68 ? 312 MET A O 1 ATOM 2197 C CB . MET A 1 285 ? -15.479 -32.808 -32.697 1.00 156.17 ? 312 MET A CB 1 ATOM 2198 C CG . MET A 1 285 ? -14.831 -33.034 -34.056 1.00 154.67 ? 312 MET A CG 1 ATOM 2199 S SD . MET A 1 285 ? -14.934 -31.639 -35.186 1.00 156.87 ? 312 MET A SD 1 ATOM 2200 C CE . MET A 1 285 ? -14.047 -32.296 -36.597 1.00 156.30 ? 312 MET A CE 1 ATOM 2201 N N . SER A 1 286 ? -16.677 -35.039 -30.371 1.00 146.30 ? 313 SER A N 1 ATOM 2202 C CA . SER A 1 286 ? -17.931 -35.758 -30.266 1.00 145.67 ? 313 SER A CA 1 ATOM 2203 C C . SER A 1 286 ? -19.053 -34.740 -30.150 1.00 144.05 ? 313 SER A C 1 ATOM 2204 O O . SER A 1 286 ? -18.857 -33.556 -30.403 1.00 143.59 ? 313 SER A O 1 ATOM 2205 C CB . SER A 1 286 ? -17.923 -36.712 -29.070 1.00 148.74 ? 313 SER A CB 1 ATOM 2206 O OG . SER A 1 286 ? -17.186 -37.888 -29.366 1.00 144.56 ? 313 SER A OG 1 ATOM 2207 N N . THR A 1 287 ? -20.209 -35.209 -29.701 1.00 143.52 ? 314 THR A N 1 ATOM 2208 C CA . THR A 1 287 ? -21.388 -34.375 -29.475 1.00 147.45 ? 314 THR A CA 1 ATOM 2209 C C . THR A 1 287 ? -21.341 -33.717 -28.100 1.00 146.84 ? 314 THR A C 1 ATOM 2210 O O . THR A 1 287 ? -22.233 -32.957 -27.726 1.00 147.31 ? 314 THR A O 1 ATOM 2211 C CB . THR A 1 287 ? -22.689 -35.186 -29.621 1.00 155.99 ? 314 THR A CB 1 ATOM 2212 O OG1 . THR A 1 287 ? -22.553 -36.442 -28.947 1.00 165.27 ? 314 THR A OG1 1 ATOM 2213 C CG2 . THR A 1 287 ? -22.987 -35.447 -31.090 1.00 134.25 ? 314 THR A CG2 1 ATOM 2214 N N . LEU A 1 288 ? -20.290 -34.021 -27.348 1.00 142.27 ? 315 LEU A N 1 ATOM 2215 C CA . LEU A 1 288 ? -20.124 -33.473 -26.012 1.00 146.17 ? 315 LEU A CA 1 ATOM 2216 C C . LEU A 1 288 ? -18.886 -32.589 -25.964 1.00 146.88 ? 315 LEU A C 1 ATOM 2217 O O . LEU A 1 288 ? -18.059 -32.683 -25.060 1.00 147.53 ? 315 LEU A O 1 ATOM 2218 C CB . LEU A 1 288 ? -20.037 -34.604 -24.987 1.00 143.82 ? 315 LEU A CB 1 ATOM 2219 C CG . LEU A 1 288 ? -20.714 -34.394 -23.630 1.00 146.45 ? 315 LEU A CG 1 ATOM 2220 C CD1 . LEU A 1 288 ? -21.949 -33.528 -23.781 1.00 146.03 ? 315 LEU A CD1 1 ATOM 2221 C CD2 . LEU A 1 288 ? -21.075 -35.736 -23.004 1.00 135.65 ? 315 LEU A CD2 1 ATOM 2222 N N . GLY A 1 289 ? -18.809 -31.699 -26.951 1.00 144.80 ? 316 GLY A N 1 ATOM 2223 C CA . GLY A 1 289 ? -17.753 -30.715 -27.060 1.00 141.35 ? 316 GLY A CA 1 ATOM 2224 C C . GLY A 1 289 ? -16.621 -31.023 -28.016 1.00 144.10 ? 316 GLY A C 1 ATOM 2225 O O . GLY A 1 289 ? -16.433 -32.163 -28.450 1.00 141.40 ? 316 GLY A O 1 ATOM 2226 N N . VAL A 1 290 ? -15.865 -29.973 -28.341 1.00 150.55 ? 317 VAL A N 1 ATOM 2227 C CA . VAL A 1 290 ? -14.734 -30.082 -29.252 1.00 146.95 ? 317 VAL A CA 1 ATOM 2228 C C . VAL A 1 290 ? -13.437 -29.964 -28.427 1.00 143.91 ? 317 VAL A C 1 ATOM 2229 O O . VAL A 1 290 ? -13.312 -29.050 -27.608 1.00 150.89 ? 317 VAL A O 1 ATOM 2230 C CB . VAL A 1 290 ? -14.777 -28.959 -30.290 1.00 145.23 ? 317 VAL A CB 1 ATOM 2231 C CG1 . VAL A 1 290 ? -13.327 -28.610 -30.743 1.00 141.35 ? 317 VAL A CG1 1 ATOM 2232 C CG2 . VAL A 1 290 ? -15.554 -29.413 -31.504 1.00 146.80 ? 317 VAL A CG2 1 ATOM 2233 N N . ILE A 1 291 ? -12.478 -30.868 -28.608 1.00 137.56 ? 318 ILE A N 1 ATOM 2234 C CA . ILE A 1 291 ? -11.188 -30.666 -27.946 1.00 146.35 ? 318 ILE A CA 1 ATOM 2235 C C . ILE A 1 291 ? -10.028 -30.491 -28.924 1.00 157.79 ? 318 ILE A C 1 ATOM 2236 O O . ILE A 1 291 ? -10.076 -30.958 -30.064 1.00 160.26 ? 318 ILE A O 1 ATOM 2237 C CB . ILE A 1 291 ? -10.875 -31.846 -27.013 1.00 142.26 ? 318 ILE A CB 1 ATOM 2238 C CG1 . ILE A 1 291 ? -10.623 -33.093 -27.856 1.00 145.52 ? 318 ILE A CG1 1 ATOM 2239 C CG2 . ILE A 1 291 ? -12.047 -32.121 -26.088 1.00 137.91 ? 318 ILE A CG2 1 ATOM 2240 C CD1 . ILE A 1 291 ? -10.315 -34.328 -27.073 1.00 144.91 ? 318 ILE A CD1 1 ATOM 2241 N N . GLU A 1 292 ? -8.996 -29.791 -28.466 1.00 164.04 ? 319 GLU A N 1 ATOM 2242 C CA . GLU A 1 292 ? -7.814 -29.501 -29.269 1.00 165.56 ? 319 GLU A CA 1 ATOM 2243 C C . GLU A 1 292 ? -6.505 -29.813 -28.549 1.00 170.33 ? 319 GLU A C 1 ATOM 2244 O O . GLU A 1 292 ? -6.486 -29.997 -27.334 1.00 170.82 ? 319 GLU A O 1 ATOM 2245 C CB . GLU A 1 292 ? -7.812 -28.042 -29.719 1.00 172.11 ? 319 GLU A CB 1 ATOM 2246 C CG . GLU A 1 292 ? -8.847 -27.724 -30.776 1.00 170.44 ? 319 GLU A CG 1 ATOM 2247 C CD . GLU A 1 292 ? -8.834 -26.266 -31.174 1.00 172.81 ? 319 GLU A CD 1 ATOM 2248 O OE1 . GLU A 1 292 ? -8.678 -25.972 -32.378 1.00 164.13 ? 319 GLU A OE1 1 ATOM 2249 O OE2 . GLU A 1 292 ? -8.979 -25.411 -30.275 1.00 184.18 ? 319 GLU A OE2 1 ATOM 2250 N N . ALA A 1 293 ? -5.421 -29.853 -29.320 1.00 171.75 ? 320 ALA A N 1 ATOM 2251 C CA . ALA A 1 293 ? -4.078 -30.146 -28.826 1.00 178.57 ? 320 ALA A CA 1 ATOM 2252 C C . ALA A 1 293 ? -3.118 -29.971 -29.995 1.00 175.60 ? 320 ALA A C 1 ATOM 2253 O O . ALA A 1 293 ? -3.340 -30.535 -31.066 1.00 179.82 ? 320 ALA A O 1 ATOM 2254 C CB . ALA A 1 293 ? -3.986 -31.557 -28.252 1.00 176.84 ? 320 ALA A CB 1 ATOM 2255 N N . ILE A 1 294 ? -2.053 -29.197 -29.796 1.00 174.53 ? 321 ILE A N 1 ATOM 2256 C CA . ILE A 1 294 ? -1.195 -28.815 -30.916 1.00 177.19 ? 321 ILE A CA 1 ATOM 2257 C C . ILE A 1 294 ? 0.156 -29.538 -30.892 1.00 182.55 ? 321 ILE A C 1 ATOM 2258 O O . ILE A 1 294 ? 0.626 -29.922 -29.821 1.00 184.16 ? 321 ILE A O 1 ATOM 2259 C CB . ILE A 1 294 ? -0.957 -27.278 -30.909 1.00 170.63 ? 321 ILE A CB 1 ATOM 2260 C CG1 . ILE A 1 294 ? -2.266 -26.536 -30.622 1.00 165.66 ? 321 ILE A CG1 1 ATOM 2261 C CG2 . ILE A 1 294 ? -0.336 -26.797 -32.219 1.00 173.01 ? 321 ILE A CG2 1 ATOM 2262 C CD1 . ILE A 1 294 ? -2.085 -25.062 -30.316 1.00 158.22 ? 321 ILE A CD1 1 ATOM 2263 N N . ALA A 1 295 ? 0.785 -29.726 -32.051 1.00 183.14 ? 322 ALA A N 1 ATOM 2264 C CA . ALA A 1 295 ? 2.179 -30.153 -32.061 1.00 180.82 ? 322 ALA A CA 1 ATOM 2265 C C . ALA A 1 295 ? 3.024 -29.118 -32.803 1.00 181.41 ? 322 ALA A C 1 ATOM 2266 O O . ALA A 1 295 ? 2.614 -28.627 -33.855 1.00 184.95 ? 322 ALA A O 1 ATOM 2267 C CB . ALA A 1 295 ? 2.320 -31.522 -32.702 1.00 178.71 ? 322 ALA A CB 1 ATOM 2268 N N . GLN A 1 296 ? 4.193 -28.788 -32.266 1.00 175.04 ? 323 GLN A N 1 ATOM 2269 C CA . GLN A 1 296 ? 5.126 -27.894 -32.940 1.00 170.21 ? 323 GLN A CA 1 ATOM 2270 C C . GLN A 1 296 ? 6.143 -28.717 -33.724 1.00 177.49 ? 323 GLN A C 1 ATOM 2271 O O . GLN A 1 296 ? 6.926 -29.456 -33.125 1.00 182.75 ? 323 GLN A O 1 ATOM 2272 C CB . GLN A 1 296 ? 5.806 -26.956 -31.943 1.00 174.87 ? 323 GLN A CB 1 ATOM 2273 C CG . GLN A 1 296 ? 4.812 -26.139 -31.124 1.00 175.74 ? 323 GLN A CG 1 ATOM 2274 C CD . GLN A 1 296 ? 5.364 -24.795 -30.692 1.00 171.83 ? 323 GLN A CD 1 ATOM 2275 O OE1 . GLN A 1 296 ? 5.089 -24.321 -29.588 1.00 147.01 ? 323 GLN A OE1 1 ATOM 2276 N NE2 . GLN A 1 296 ? 6.141 -24.167 -31.567 1.00 182.95 ? 323 GLN A NE2 1 ATOM 2277 N N . ILE A 1 297 ? 6.159 -28.589 -35.045 1.00 179.57 ? 324 ILE A N 1 ATOM 2278 C CA . ILE A 1 297 ? 7.206 -29.232 -35.831 1.00 187.00 ? 324 ILE A CA 1 ATOM 2279 C C . ILE A 1 297 ? 8.142 -28.143 -36.342 1.00 190.88 ? 324 ILE A C 1 ATOM 2280 O O . ILE A 1 297 ? 7.742 -27.281 -37.126 1.00 189.78 ? 324 ILE A O 1 ATOM 2281 C CB . ILE A 1 297 ? 6.638 -30.066 -37.001 1.00 185.20 ? 324 ILE A CB 1 ATOM 2282 C CG1 . ILE A 1 297 ? 5.723 -31.181 -36.476 1.00 182.44 ? 324 ILE A CG1 1 ATOM 2283 C CG2 . ILE A 1 297 ? 7.767 -30.652 -37.839 1.00 185.27 ? 324 ILE A CG2 1 ATOM 2284 C CD1 . ILE A 1 297 ? 6.271 -31.935 -35.283 1.00 177.12 ? 324 ILE A CD1 1 ATOM 2285 N N . THR A 1 298 ? 9.392 -28.191 -35.896 1.00 193.87 ? 325 THR A N 1 ATOM 2286 C CA . THR A 1 298 ? 10.392 -27.219 -36.317 1.00 192.97 ? 325 THR A CA 1 ATOM 2287 C C . THR A 1 298 ? 11.674 -27.921 -36.762 1.00 192.98 ? 325 THR A C 1 ATOM 2288 O O . THR A 1 298 ? 12.082 -28.922 -36.173 1.00 191.50 ? 325 THR A O 1 ATOM 2289 C CB . THR A 1 298 ? 10.715 -26.221 -35.182 1.00 194.65 ? 325 THR A CB 1 ATOM 2290 O OG1 . THR A 1 298 ? 10.727 -26.910 -33.925 1.00 191.35 ? 325 THR A OG1 1 ATOM 2291 C CG2 . THR A 1 298 ? 9.664 -25.126 -35.119 1.00 183.65 ? 325 THR A CG2 1 ATOM 2292 N N . VAL A 1 299 ? 12.305 -27.376 -37.798 1.00 189.55 ? 326 VAL A N 1 ATOM 2293 C CA . VAL A 1 299 ? 13.677 -27.710 -38.136 1.00 195.21 ? 326 VAL A CA 1 ATOM 2294 C C . VAL A 1 299 ? 14.737 -26.638 -37.856 1.00 197.53 ? 326 VAL A C 1 ATOM 2295 O O . VAL A 1 299 ? 14.593 -25.487 -38.275 1.00 196.54 ? 326 VAL A O 1 ATOM 2296 C CB . VAL A 1 299 ? 13.776 -28.061 -39.646 1.00 195.68 ? 326 VAL A CB 1 ATOM 2297 C CG1 . VAL A 1 299 ? 12.970 -27.071 -40.485 1.00 183.72 ? 326 VAL A CG1 1 ATOM 2298 C CG2 . VAL A 1 299 ? 15.220 -28.099 -40.094 1.00 201.41 ? 326 VAL A CG2 1 ATOM 2299 N N . LYS A 1 300 ? 15.778 -27.006 -37.107 1.00 196.66 ? 327 LYS A N 1 ATOM 2300 C CA . LYS A 1 300 ? 16.930 -26.136 -36.899 1.00 195.88 ? 327 LYS A CA 1 ATOM 2301 C C . LYS A 1 300 ? 17.990 -26.461 -37.934 1.00 201.06 ? 327 LYS A C 1 ATOM 2302 O O . LYS A 1 300 ? 17.955 -27.516 -38.560 1.00 192.84 ? 327 LYS A O 1 ATOM 2303 C CB . LYS A 1 300 ? 17.524 -26.287 -35.487 1.00 190.61 ? 327 LYS A CB 1 ATOM 2304 C CG . LYS A 1 300 ? 17.480 -27.714 -34.966 1.00 194.66 ? 327 LYS A CG 1 ATOM 2305 C CD . LYS A 1 300 ? 17.480 -27.778 -33.435 1.00 188.51 ? 327 LYS A CD 1 ATOM 2306 C CE . LYS A 1 300 ? 18.891 -27.840 -32.884 1.00 183.23 ? 327 LYS A CE 1 ATOM 2307 N NZ . LYS A 1 300 ? 19.489 -29.145 -33.214 1.00 187.33 ? 327 LYS A NZ 1 ATOM 2308 N N . ALA A 1 301 ? 18.942 -25.552 -38.087 1.00 209.87 ? 328 ALA A N 1 ATOM 2309 C CA . ALA A 1 301 ? 20.036 -25.773 -39.007 1.00 202.92 ? 328 ALA A CA 1 ATOM 2310 C C . ALA A 1 301 ? 21.382 -25.373 -38.404 1.00 198.82 ? 328 ALA A C 1 ATOM 2311 O O . ALA A 1 301 ? 22.430 -25.772 -38.919 1.00 194.51 ? 328 ALA A O 1 ATOM 2312 C CB . ALA A 1 301 ? 19.794 -25.030 -40.301 1.00 191.55 ? 328 ALA A CB 1 ATOM 2313 N N . LEU A 1 302 ? 21.365 -24.593 -37.322 1.00 196.95 ? 329 LEU A N 1 ATOM 2314 C CA . LEU A 1 302 ? 22.613 -24.254 -36.630 1.00 189.26 ? 329 LEU A CA 1 ATOM 2315 C C . LEU A 1 302 ? 22.496 -23.628 -35.236 1.00 192.51 ? 329 LEU A C 1 ATOM 2316 O O . LEU A 1 302 ? 21.506 -22.952 -34.939 1.00 191.37 ? 329 LEU A O 1 ATOM 2317 C CB . LEU A 1 302 ? 23.415 -23.289 -37.520 1.00 186.14 ? 329 LEU A CB 1 ATOM 2318 C CG . LEU A 1 302 ? 22.675 -22.067 -38.072 1.00 177.93 ? 329 LEU A CG 1 ATOM 2319 C CD1 . LEU A 1 302 ? 22.682 -20.894 -37.099 1.00 177.13 ? 329 LEU A CD1 1 ATOM 2320 C CD2 . LEU A 1 302 ? 23.246 -21.649 -39.420 1.00 178.26 ? 329 LEU A CD2 1 ATOM 2321 N N . PRO A 1 303 ? 23.495 -23.892 -34.376 1.00 196.65 ? 330 PRO A N 1 ATOM 2322 C CA . PRO A 1 303 ? 23.610 -23.349 -33.020 1.00 195.34 ? 330 PRO A CA 1 ATOM 2323 C C . PRO A 1 303 ? 23.702 -21.833 -33.147 1.00 194.39 ? 330 PRO A C 1 ATOM 2324 O O . PRO A 1 303 ? 24.218 -21.393 -34.172 1.00 194.34 ? 330 PRO A O 1 ATOM 2325 C CB . PRO A 1 303 ? 24.909 -23.963 -32.488 1.00 193.49 ? 330 PRO A CB 1 ATOM 2326 C CG . PRO A 1 303 ? 25.143 -25.141 -33.324 1.00 194.10 ? 330 PRO A CG 1 ATOM 2327 C CD . PRO A 1 303 ? 24.596 -24.820 -34.679 1.00 195.74 ? 330 PRO A CD 1 ATOM 2328 N N . LYS A 1 304 ? 23.248 -21.040 -32.181 1.00 192.94 ? 331 LYS A N 1 ATOM 2329 C CA . LYS A 1 304 ? 23.653 -19.637 -32.253 1.00 190.91 ? 331 LYS A CA 1 ATOM 2330 C C . LYS A 1 304 ? 25.096 -19.463 -31.786 1.00 191.72 ? 331 LYS A C 1 ATOM 2331 O O . LYS A 1 304 ? 25.664 -20.362 -31.165 1.00 193.45 ? 331 LYS A O 1 ATOM 2332 C CB . LYS A 1 304 ? 22.709 -18.756 -31.411 1.00 185.69 ? 331 LYS A CB 1 ATOM 2333 C CG . LYS A 1 304 ? 21.309 -18.469 -31.986 1.00 177.87 ? 331 LYS A CG 1 ATOM 2334 C CD . LYS A 1 304 ? 20.910 -19.345 -33.162 1.00 178.77 ? 331 LYS A CD 1 ATOM 2335 C CE . LYS A 1 304 ? 19.855 -20.356 -32.745 1.00 172.18 ? 331 LYS A CE 1 ATOM 2336 N NZ . LYS A 1 304 ? 18.605 -19.685 -32.289 1.00 159.76 ? 331 LYS A NZ 1 ATOM 2337 N N . PRO A 1 305 ? 25.692 -18.300 -32.101 1.00 187.68 ? 332 PRO A N 1 ATOM 2338 C CA . PRO A 1 305 ? 27.057 -17.953 -31.696 1.00 183.87 ? 332 PRO A CA 1 ATOM 2339 C C . PRO A 1 305 ? 27.186 -17.817 -30.186 1.00 189.70 ? 332 PRO A C 1 ATOM 2340 O O . PRO A 1 305 ? 26.247 -17.335 -29.554 1.00 195.29 ? 332 PRO A O 1 ATOM 2341 C CB . PRO A 1 305 ? 27.313 -16.600 -32.390 1.00 179.43 ? 332 PRO A CB 1 ATOM 2342 C CG . PRO A 1 305 ? 25.994 -16.180 -32.974 1.00 177.87 ? 332 PRO A CG 1 ATOM 2343 C CD . PRO A 1 305 ? 25.232 -17.435 -33.199 1.00 183.71 ? 332 PRO A CD 1 ATOM 2344 N N . PRO A 1 306 ? 28.311 -18.259 -29.607 1.00 191.94 ? 333 PRO A N 1 ATOM 2345 C CA . PRO A 1 306 ? 28.448 -18.039 -28.166 1.00 199.84 ? 333 PRO A CA 1 ATOM 2346 C C . PRO A 1 306 ? 28.453 -16.549 -27.819 1.00 193.99 ? 333 PRO A C 1 ATOM 2347 O O . PRO A 1 306 ? 28.598 -15.691 -28.691 1.00 191.01 ? 333 PRO A O 1 ATOM 2348 C CB . PRO A 1 306 ? 29.790 -18.696 -27.825 1.00 201.03 ? 333 PRO A CB 1 ATOM 2349 C CG . PRO A 1 306 ? 30.053 -19.653 -28.949 1.00 192.70 ? 333 PRO A CG 1 ATOM 2350 C CD . PRO A 1 306 ? 29.399 -19.077 -30.162 1.00 192.97 ? 333 PRO A CD 1 ATOM 2351 N N . GLY A 1 307 ? 28.283 -16.254 -26.538 1.00 187.60 ? 334 GLY A N 1 ATOM 2352 C CA . GLY A 1 307 ? 28.409 -14.901 -26.041 1.00 182.44 ? 334 GLY A CA 1 ATOM 2353 C C . GLY A 1 307 ? 29.463 -14.841 -24.959 1.00 195.77 ? 334 GLY A C 1 ATOM 2354 O O . GLY A 1 307 ? 29.785 -15.860 -24.346 1.00 199.56 ? 334 GLY A O 1 ATOM 2355 N N . THR A 1 308 ? 30.027 -13.650 -24.774 1.00 201.70 ? 335 THR A N 1 ATOM 2356 C CA . THR A 1 308 ? 31.007 -13.349 -23.727 1.00 211.21 ? 335 THR A CA 1 ATOM 2357 C C . THR A 1 308 ? 32.415 -13.943 -23.882 1.00 209.70 ? 335 THR A C 1 ATOM 2358 O O . THR A 1 308 ? 32.979 -14.418 -22.896 1.00 211.81 ? 335 THR A O 1 ATOM 2359 C CB . THR A 1 308 ? 30.491 -13.787 -22.317 1.00 215.14 ? 335 THR A CB 1 ATOM 2360 O OG1 . THR A 1 308 ? 30.458 -15.218 -22.229 1.00 215.79 ? 335 THR A OG1 1 ATOM 2361 C CG2 . THR A 1 308 ? 29.101 -13.226 -22.036 1.00 213.70 ? 335 THR A CG2 1 ATOM 2362 N N . PRO A 1 309 ? 32.982 -13.946 -25.105 1.00 204.17 ? 336 PRO A N 1 ATOM 2363 C CA . PRO A 1 309 ? 34.311 -14.563 -25.198 1.00 198.85 ? 336 PRO A CA 1 ATOM 2364 C C . PRO A 1 309 ? 35.303 -13.707 -24.396 1.00 197.25 ? 336 PRO A C 1 ATOM 2365 O O . PRO A 1 309 ? 35.978 -12.844 -24.959 1.00 193.96 ? 336 PRO A O 1 ATOM 2366 C CB . PRO A 1 309 ? 34.606 -14.572 -26.702 1.00 192.36 ? 336 PRO A CB 1 ATOM 2367 C CG . PRO A 1 309 ? 33.638 -13.602 -27.324 1.00 191.91 ? 336 PRO A CG 1 ATOM 2368 C CD . PRO A 1 309 ? 32.670 -13.118 -26.282 1.00 193.37 ? 336 PRO A CD 1 ATOM 2369 N N . VAL A 1 310 ? 35.383 -13.977 -23.092 1.00 199.97 ? 337 VAL A N 1 ATOM 2370 C CA . VAL A 1 310 ? 36.222 -13.222 -22.156 1.00 194.61 ? 337 VAL A CA 1 ATOM 2371 C C . VAL A 1 310 ? 37.314 -14.050 -21.448 1.00 189.87 ? 337 VAL A C 1 ATOM 2372 O O . VAL A 1 310 ? 37.079 -15.150 -20.948 1.00 195.58 ? 337 VAL A O 1 ATOM 2373 C CB . VAL A 1 310 ? 35.344 -12.516 -21.096 1.00 191.57 ? 337 VAL A CB 1 ATOM 2374 C CG1 . VAL A 1 310 ? 36.203 -11.700 -20.144 1.00 179.38 ? 337 VAL A CG1 1 ATOM 2375 C CG2 . VAL A 1 310 ? 34.323 -11.612 -21.785 1.00 190.93 ? 337 VAL A CG2 1 ATOM 2376 N N . VAL A 1 311 ? 38.505 -13.458 -21.425 1.00 176.93 ? 338 VAL A N 1 ATOM 2377 C CA . VAL A 1 311 ? 39.736 -13.936 -20.786 1.00 170.90 ? 338 VAL A CA 1 ATOM 2378 C C . VAL A 1 311 ? 39.866 -13.702 -19.271 1.00 167.83 ? 338 VAL A C 1 ATOM 2379 O O . VAL A 1 311 ? 39.830 -12.562 -18.808 1.00 163.10 ? 338 VAL A O 1 ATOM 2380 C CB . VAL A 1 311 ? 40.960 -13.291 -21.465 1.00 178.05 ? 338 VAL A CB 1 ATOM 2381 C CG1 . VAL A 1 311 ? 42.241 -13.642 -20.723 1.00 171.88 ? 338 VAL A CG1 1 ATOM 2382 C CG2 . VAL A 1 311 ? 41.036 -13.725 -22.916 1.00 187.29 ? 338 VAL A CG2 1 ATOM 2383 N N . THR A 1 312 ? 40.002 -14.788 -18.507 1.00 174.59 ? 339 THR A N 1 ATOM 2384 C CA . THR A 1 312 ? 40.059 -14.742 -17.038 1.00 184.63 ? 339 THR A CA 1 ATOM 2385 C C . THR A 1 312 ? 41.480 -15.060 -16.548 1.00 185.74 ? 339 THR A C 1 ATOM 2386 O O . THR A 1 312 ? 41.811 -14.827 -15.384 1.00 182.91 ? 339 THR A O 1 ATOM 2387 C CB . THR A 1 312 ? 39.065 -15.731 -16.385 1.00 184.71 ? 339 THR A CB 1 ATOM 2388 O OG1 . THR A 1 312 ? 39.133 -15.613 -14.958 1.00 185.43 ? 339 THR A OG1 1 ATOM 2389 C CG2 . THR A 1 312 ? 39.395 -17.162 -16.776 1.00 182.66 ? 339 THR A CG2 1 ATOM 2390 N N . GLU A 1 313 ? 42.311 -15.568 -17.457 1.00 181.20 ? 340 GLU A N 1 ATOM 2391 C CA . GLU A 1 313 ? 43.735 -15.821 -17.211 1.00 180.11 ? 340 GLU A CA 1 ATOM 2392 C C . GLU A 1 313 ? 44.444 -15.674 -18.553 1.00 182.01 ? 340 GLU A C 1 ATOM 2393 O O . GLU A 1 313 ? 43.918 -16.054 -19.597 1.00 179.91 ? 340 GLU A O 1 ATOM 2394 C CB . GLU A 1 313 ? 44.007 -17.205 -16.600 1.00 172.26 ? 340 GLU A CB 1 ATOM 2395 C CG . GLU A 1 313 ? 43.497 -17.417 -15.182 1.00 156.06 ? 340 GLU A CG 1 ATOM 2396 C CD . GLU A 1 313 ? 44.628 -17.431 -14.157 1.00 136.05 ? 340 GLU A CD 1 ATOM 2397 O OE1 . GLU A 1 313 ? 45.782 -17.136 -14.538 1.00 136.48 ? 340 GLU A OE1 1 ATOM 2398 O OE2 . GLU A 1 313 ? 44.359 -17.723 -12.976 1.00 122.36 ? 340 GLU A OE2 1 ATOM 2399 N N . SER A 1 314 ? 45.658 -15.137 -18.497 1.00 183.11 ? 341 SER A N 1 ATOM 2400 C CA . SER A 1 314 ? 46.545 -15.008 -19.650 1.00 174.97 ? 341 SER A CA 1 ATOM 2401 C C . SER A 1 314 ? 48.028 -15.166 -19.326 1.00 179.88 ? 341 SER A C 1 ATOM 2402 O O . SER A 1 314 ? 48.471 -14.779 -18.243 1.00 183.20 ? 341 SER A O 1 ATOM 2403 C CB . SER A 1 314 ? 46.314 -13.653 -20.325 1.00 167.62 ? 341 SER A CB 1 ATOM 2404 O OG . SER A 1 314 ? 47.441 -13.262 -21.089 1.00 167.86 ? 341 SER A OG 1 ATOM 2405 N N . THR A 1 315 ? 48.797 -15.724 -20.258 1.00 182.51 ? 342 THR A N 1 ATOM 2406 C CA . THR A 1 315 ? 50.245 -15.699 -20.105 1.00 186.23 ? 342 THR A CA 1 ATOM 2407 C C . THR A 1 315 ? 50.836 -15.107 -21.384 1.00 179.49 ? 342 THR A C 1 ATOM 2408 O O . THR A 1 315 ? 50.090 -14.715 -22.286 1.00 176.58 ? 342 THR A O 1 ATOM 2409 C CB . THR A 1 315 ? 50.832 -17.110 -19.852 1.00 190.94 ? 342 THR A CB 1 ATOM 2410 O OG1 . THR A 1 315 ? 50.660 -17.919 -21.024 1.00 194.04 ? 342 THR A OG1 1 ATOM 2411 C CG2 . THR A 1 315 ? 50.130 -17.788 -18.679 1.00 184.18 ? 342 THR A CG2 1 ATOM 2412 N N . ALA A 1 316 ? 52.161 -15.013 -21.465 1.00 172.35 ? 343 ALA A N 1 ATOM 2413 C CA . ALA A 1 316 ? 52.801 -14.532 -22.691 1.00 171.77 ? 343 ALA A CA 1 ATOM 2414 C C . ALA A 1 316 ? 52.608 -15.376 -23.948 1.00 181.65 ? 343 ALA A C 1 ATOM 2415 O O . ALA A 1 316 ? 52.671 -14.844 -25.049 1.00 184.48 ? 343 ALA A O 1 ATOM 2416 C CB . ALA A 1 316 ? 54.290 -14.351 -22.434 1.00 173.51 ? 343 ALA A CB 1 ATOM 2417 N N . THR A 1 317 ? 52.311 -16.662 -23.795 1.00 185.12 ? 344 THR A N 1 ATOM 2418 C CA . THR A 1 317 ? 52.243 -17.549 -24.958 1.00 188.27 ? 344 THR A CA 1 ATOM 2419 C C . THR A 1 317 ? 50.966 -18.368 -24.944 1.00 185.81 ? 344 THR A C 1 ATOM 2420 O O . THR A 1 317 ? 50.784 -19.274 -25.756 1.00 186.39 ? 344 THR A O 1 ATOM 2421 C CB . THR A 1 317 ? 53.452 -18.516 -25.037 1.00 188.45 ? 344 THR A CB 1 ATOM 2422 O OG1 . THR A 1 317 ? 53.438 -19.404 -23.913 1.00 190.21 ? 344 THR A OG1 1 ATOM 2423 C CG2 . THR A 1 317 ? 54.769 -17.749 -25.066 1.00 189.39 ? 344 THR A CG2 1 ATOM 2424 N N . SER A 1 318 ? 50.079 -18.032 -24.019 1.00 185.79 ? 345 SER A N 1 ATOM 2425 C CA . SER A 1 318 ? 48.791 -18.690 -23.936 1.00 188.27 ? 345 SER A CA 1 ATOM 2426 C C . SER A 1 318 ? 47.773 -17.671 -23.458 1.00 194.42 ? 345 SER A C 1 ATOM 2427 O O . SER A 1 318 ? 48.123 -16.665 -22.843 1.00 190.94 ? 345 SER A O 1 ATOM 2428 C CB . SER A 1 318 ? 48.852 -19.903 -23.004 1.00 188.55 ? 345 SER A CB 1 ATOM 2429 O OG . SER A 1 318 ? 49.763 -20.874 -23.490 1.00 185.82 ? 345 SER A OG 1 ATOM 2430 N N . ILE A 1 319 ? 46.509 -17.953 -23.736 1.00 201.06 ? 346 ILE A N 1 ATOM 2431 C CA . ILE A 1 319 ? 45.384 -17.174 -23.235 1.00 198.84 ? 346 ILE A CA 1 ATOM 2432 C C . ILE A 1 319 ? 44.253 -18.080 -22.771 1.00 198.21 ? 346 ILE A C 1 ATOM 2433 O O . ILE A 1 319 ? 43.863 -18.990 -23.499 1.00 195.11 ? 346 ILE A O 1 ATOM 2434 C CB . ILE A 1 319 ? 44.832 -16.196 -24.301 1.00 186.71 ? 346 ILE A CB 1 ATOM 2435 C CG1 . ILE A 1 319 ? 45.936 -15.699 -25.236 1.00 175.79 ? 346 ILE A CG1 1 ATOM 2436 C CG2 . ILE A 1 319 ? 44.164 -15.020 -23.632 1.00 180.45 ? 346 ILE A CG2 1 ATOM 2437 C CD1 . ILE A 1 319 ? 45.482 -15.497 -26.662 1.00 169.47 ? 346 ILE A CD1 1 ATOM 2438 N N . THR A 1 320 ? 43.717 -17.866 -21.574 1.00 192.63 ? 347 THR A N 1 ATOM 2439 C CA . THR A 1 320 ? 42.637 -18.742 -21.161 1.00 183.97 ? 347 THR A CA 1 ATOM 2440 C C . THR A 1 320 ? 41.362 -17.950 -21.384 1.00 180.99 ? 347 THR A C 1 ATOM 2441 O O . THR A 1 320 ? 41.186 -16.841 -20.874 1.00 173.24 ? 347 THR A O 1 ATOM 2442 C CB . THR A 1 320 ? 42.759 -19.166 -19.679 1.00 169.61 ? 347 THR A CB 1 ATOM 2443 O OG1 . THR A 1 320 ? 43.997 -19.859 -19.472 1.00 159.52 ? 347 THR A OG1 1 ATOM 2444 C CG2 . THR A 1 320 ? 41.604 -20.070 -19.280 1.00 171.48 ? 347 THR A CG2 1 ATOM 2445 N N . LEU A 1 321 ? 40.473 -18.559 -22.162 1.00 185.43 ? 348 LEU A N 1 ATOM 2446 C CA . LEU A 1 321 ? 39.218 -17.953 -22.582 1.00 182.71 ? 348 LEU A CA 1 ATOM 2447 C C . LEU A 1 321 ? 38.035 -18.614 -21.901 1.00 188.09 ? 348 LEU A C 1 ATOM 2448 O O . LEU A 1 321 ? 38.049 -19.818 -21.643 1.00 190.00 ? 348 LEU A O 1 ATOM 2449 C CB . LEU A 1 321 ? 39.071 -18.040 -24.105 1.00 181.46 ? 348 LEU A CB 1 ATOM 2450 C CG . LEU A 1 321 ? 38.014 -17.132 -24.736 1.00 188.05 ? 348 LEU A CG 1 ATOM 2451 C CD1 . LEU A 1 321 ? 38.477 -15.682 -24.730 1.00 185.23 ? 348 LEU A CD1 1 ATOM 2452 C CD2 . LEU A 1 321 ? 37.668 -17.588 -26.145 1.00 193.88 ? 348 LEU A CD2 1 ATOM 2453 N N . THR A 1 322 ? 37.012 -17.821 -21.608 1.00 188.01 ? 349 THR A N 1 ATOM 2454 C CA . THR A 1 322 ? 35.723 -18.360 -21.207 1.00 184.30 ? 349 THR A CA 1 ATOM 2455 C C . THR A 1 322 ? 34.559 -17.740 -21.966 1.00 186.83 ? 349 THR A C 1 ATOM 2456 O O . THR A 1 322 ? 34.627 -16.576 -22.358 1.00 189.94 ? 349 THR A O 1 ATOM 2457 C CB . THR A 1 322 ? 35.465 -18.109 -19.705 1.00 184.64 ? 349 THR A CB 1 ATOM 2458 O OG1 . THR A 1 322 ? 35.299 -16.705 -19.472 1.00 194.82 ? 349 THR A OG1 1 ATOM 2459 C CG2 . THR A 1 322 ? 36.611 -18.628 -18.862 1.00 181.86 ? 349 THR A CG2 1 ATOM 2460 N N . TRP A 1 323 ? 33.495 -18.507 -22.185 1.00 189.46 ? 350 TRP A N 1 ATOM 2461 C CA . TRP A 1 323 ? 32.344 -17.965 -22.892 1.00 195.02 ? 350 TRP A CA 1 ATOM 2462 C C . TRP A 1 323 ? 31.128 -18.665 -22.302 1.00 198.53 ? 350 TRP A C 1 ATOM 2463 O O . TRP A 1 323 ? 31.237 -19.773 -21.790 1.00 197.45 ? 350 TRP A O 1 ATOM 2464 C CB . TRP A 1 323 ? 32.400 -18.199 -24.411 1.00 188.79 ? 350 TRP A CB 1 ATOM 2465 C CG . TRP A 1 323 ? 32.507 -19.644 -24.852 1.00 190.63 ? 350 TRP A CG 1 ATOM 2466 C CD1 . TRP A 1 323 ? 31.468 -20.467 -25.190 1.00 193.64 ? 350 TRP A CD1 1 ATOM 2467 C CD2 . TRP A 1 323 ? 33.703 -20.409 -25.063 1.00 195.19 ? 350 TRP A CD2 1 ATOM 2468 N NE1 . TRP A 1 323 ? 31.937 -21.701 -25.563 1.00 195.68 ? 350 TRP A NE1 1 ATOM 2469 C CE2 . TRP A 1 323 ? 33.305 -21.693 -25.498 1.00 195.16 ? 350 TRP A CE2 1 ATOM 2470 C CE3 . TRP A 1 323 ? 35.068 -20.142 -24.914 1.00 193.41 ? 350 TRP A CE3 1 ATOM 2471 C CZ2 . TRP A 1 323 ? 34.222 -22.703 -25.784 1.00 188.31 ? 350 TRP A CZ2 1 ATOM 2472 C CZ3 . TRP A 1 323 ? 35.976 -21.148 -25.199 1.00 189.07 ? 350 TRP A CZ3 1 ATOM 2473 C CH2 . TRP A 1 323 ? 35.548 -22.412 -25.629 1.00 187.58 ? 350 TRP A CH2 1 ATOM 2474 N N . ASP A 1 324 ? 29.973 -18.015 -22.376 1.00 202.26 ? 351 ASP A N 1 ATOM 2475 C CA . ASP A 1 324 ? 28.691 -18.651 -22.101 1.00 199.09 ? 351 ASP A CA 1 ATOM 2476 C C . ASP A 1 324 ? 28.303 -19.399 -23.376 1.00 198.29 ? 351 ASP A C 1 ATOM 2477 O O . ASP A 1 324 ? 28.661 -18.953 -24.466 1.00 200.42 ? 351 ASP A O 1 ATOM 2478 C CB . ASP A 1 324 ? 27.632 -17.636 -21.671 1.00 196.60 ? 351 ASP A CB 1 ATOM 2479 C CG . ASP A 1 324 ? 26.283 -18.277 -21.422 1.00 189.89 ? 351 ASP A CG 1 ATOM 2480 O OD1 . ASP A 1 324 ? 26.171 -19.041 -20.438 1.00 191.54 ? 351 ASP A OD1 1 ATOM 2481 O OD2 . ASP A 1 324 ? 25.342 -18.029 -22.202 1.00 185.34 ? 351 ASP A OD2 1 ATOM 2482 N N . SER A 1 325 ? 27.601 -20.524 -23.264 1.00 197.46 ? 352 SER A N 1 ATOM 2483 C CA . SER A 1 325 ? 27.254 -21.296 -24.458 1.00 201.62 ? 352 SER A CA 1 ATOM 2484 C C . SER A 1 325 ? 26.413 -20.477 -25.439 1.00 203.49 ? 352 SER A C 1 ATOM 2485 O O . SER A 1 325 ? 26.452 -20.697 -26.650 1.00 201.41 ? 352 SER A O 1 ATOM 2486 C CB . SER A 1 325 ? 26.476 -22.550 -24.060 1.00 200.93 ? 352 SER A CB 1 ATOM 2487 O OG . SER A 1 325 ? 26.860 -23.016 -22.781 1.00 193.26 ? 352 SER A OG 1 ATOM 2488 N N . GLY A 1 326 ? 25.648 -19.540 -24.892 1.00 201.32 ? 353 GLY A N 1 ATOM 2489 C CA . GLY A 1 326 ? 24.713 -18.727 -25.648 1.00 194.23 ? 353 GLY A CA 1 ATOM 2490 C C . GLY A 1 326 ? 23.512 -19.428 -26.250 1.00 194.66 ? 353 GLY A C 1 ATOM 2491 O O . GLY A 1 326 ? 22.727 -18.798 -26.961 1.00 179.87 ? 353 GLY A O 1 ATOM 2492 N N . ASN A 1 327 ? 23.353 -20.720 -25.980 1.00 206.72 ? 354 ASN A N 1 ATOM 2493 C CA . ASN A 1 327 ? 22.312 -21.477 -26.666 1.00 199.09 ? 354 ASN A CA 1 ATOM 2494 C C . ASN A 1 327 ? 21.345 -22.219 -25.749 1.00 198.13 ? 354 ASN A C 1 ATOM 2495 O O . ASN A 1 327 ? 21.753 -22.833 -24.762 1.00 197.43 ? 354 ASN A O 1 ATOM 2496 C CB . ASN A 1 327 ? 22.937 -22.479 -27.648 1.00 188.75 ? 354 ASN A CB 1 ATOM 2497 C CG . ASN A 1 327 ? 23.407 -21.823 -28.938 1.00 183.26 ? 354 ASN A CG 1 ATOM 2498 O OD1 . ASN A 1 327 ? 22.691 -21.824 -29.941 1.00 182.50 ? 354 ASN A OD1 1 ATOM 2499 N ND2 . ASN A 1 327 ? 24.612 -21.265 -28.917 1.00 184.71 ? 354 ASN A ND2 1 ATOM 2500 N N . PRO A 1 328 ? 20.051 -22.160 -26.092 1.00 191.77 ? 355 PRO A N 1 ATOM 2501 C CA . PRO A 1 328 ? 18.913 -22.824 -25.452 1.00 184.14 ? 355 PRO A CA 1 ATOM 2502 C C . PRO A 1 328 ? 18.946 -24.338 -25.665 1.00 190.07 ? 355 PRO A C 1 ATOM 2503 O O . PRO A 1 328 ? 18.627 -25.104 -24.756 1.00 192.83 ? 355 PRO A O 1 ATOM 2504 C CB . PRO A 1 328 ? 17.698 -22.186 -26.129 1.00 175.84 ? 355 PRO A CB 1 ATOM 2505 C CG . PRO A 1 328 ? 18.191 -21.757 -27.446 1.00 179.22 ? 355 PRO A CG 1 ATOM 2506 C CD . PRO A 1 328 ? 19.606 -21.309 -27.211 1.00 187.64 ? 355 PRO A CD 1 ATOM 2507 N N . GLU A 1 329 ? 19.368 -24.746 -26.862 1.00 189.26 ? 356 GLU A N 1 ATOM 2508 C CA . GLU A 1 329 ? 19.419 -26.155 -27.256 1.00 185.02 ? 356 GLU A CA 1 ATOM 2509 C C . GLU A 1 329 ? 20.787 -26.867 -27.163 1.00 183.42 ? 356 GLU A C 1 ATOM 2510 O O . GLU A 1 329 ? 21.824 -26.211 -27.051 1.00 181.56 ? 356 GLU A O 1 ATOM 2511 C CB . GLU A 1 329 ? 18.928 -26.234 -28.708 1.00 176.72 ? 356 GLU A CB 1 ATOM 2512 C CG . GLU A 1 329 ? 19.996 -25.820 -29.716 1.00 173.16 ? 356 GLU A CG 1 ATOM 2513 C CD . GLU A 1 329 ? 19.440 -25.053 -30.901 1.00 172.47 ? 356 GLU A CD 1 ATOM 2514 O OE1 . GLU A 1 329 ? 18.254 -25.245 -31.237 1.00 172.23 ? 356 GLU A OE1 1 ATOM 2515 O OE2 . GLU A 1 329 ? 20.195 -24.259 -31.504 1.00 176.56 ? 356 GLU A OE2 1 ATOM 2516 N N . PRO A 1 330 ? 20.777 -28.226 -27.235 1.00 178.51 ? 357 PRO A N 1 ATOM 2517 C CA . PRO A 1 330 ? 21.922 -29.158 -27.145 1.00 180.09 ? 357 PRO A CA 1 ATOM 2518 C C . PRO A 1 330 ? 22.897 -29.028 -28.322 1.00 186.67 ? 357 PRO A C 1 ATOM 2519 O O . PRO A 1 330 ? 22.601 -29.492 -29.428 1.00 183.63 ? 357 PRO A O 1 ATOM 2520 C CB . PRO A 1 330 ? 21.256 -30.540 -27.189 1.00 172.70 ? 357 PRO A CB 1 ATOM 2521 C CG . PRO A 1 330 ? 19.781 -30.295 -27.354 1.00 170.10 ? 357 PRO A CG 1 ATOM 2522 C CD . PRO A 1 330 ? 19.516 -28.918 -26.910 1.00 171.38 ? 357 PRO A CD 1 ATOM 2523 N N . VAL A 1 331 ? 24.052 -28.437 -28.064 1.00 192.63 ? 358 VAL A N 1 ATOM 2524 C CA . VAL A 1 331 ? 25.093 -28.319 -29.037 1.00 190.33 ? 358 VAL A CA 1 ATOM 2525 C C . VAL A 1 331 ? 26.089 -29.444 -28.713 1.00 188.81 ? 358 VAL A C 1 ATOM 2526 O O . VAL A 1 331 ? 26.232 -29.780 -27.537 1.00 191.27 ? 358 VAL A O 1 ATOM 2527 C CB . VAL A 1 331 ? 25.754 -26.982 -28.949 1.00 188.84 ? 358 VAL A CB 1 ATOM 2528 C CG1 . VAL A 1 331 ? 26.745 -26.895 -30.137 1.00 187.63 ? 358 VAL A CG1 1 ATOM 2529 C CG2 . VAL A 1 331 ? 24.814 -25.929 -29.437 1.00 180.86 ? 358 VAL A CG2 1 ATOM 2530 N N . SER A 1 332 ? 26.783 -30.042 -29.685 1.00 184.35 ? 359 SER A N 1 ATOM 2531 C CA . SER A 1 332 ? 27.760 -31.110 -29.385 1.00 184.96 ? 359 SER A CA 1 ATOM 2532 C C . SER A 1 332 ? 29.106 -30.576 -28.838 1.00 185.75 ? 359 SER A C 1 ATOM 2533 O O . SER A 1 332 ? 29.667 -31.123 -27.885 1.00 176.92 ? 359 SER A O 1 ATOM 2534 C CB . SER A 1 332 ? 28.022 -31.965 -30.609 1.00 189.36 ? 359 SER A CB 1 ATOM 2535 O OG . SER A 1 332 ? 28.478 -31.189 -31.701 1.00 197.43 ? 359 SER A OG 1 ATOM 2536 N N . TYR A 1 333 ? 29.605 -29.495 -29.433 1.00 194.04 ? 360 TYR A N 1 ATOM 2537 C CA . TYR A 1 333 ? 30.921 -28.949 -29.067 1.00 194.51 ? 360 TYR A CA 1 ATOM 2538 C C . TYR A 1 333 ? 31.135 -27.637 -29.797 1.00 197.21 ? 360 TYR A C 1 ATOM 2539 O O . TYR A 1 333 ? 30.275 -27.208 -30.574 1.00 198.93 ? 360 TYR A O 1 ATOM 2540 C CB . TYR A 1 333 ? 32.045 -29.907 -29.446 1.00 193.13 ? 360 TYR A CB 1 ATOM 2541 C CG . TYR A 1 333 ? 32.152 -30.106 -30.938 1.00 193.67 ? 360 TYR A CG 1 ATOM 2542 C CD1 . TYR A 1 333 ? 31.497 -31.146 -31.570 1.00 193.54 ? 360 TYR A CD1 1 ATOM 2543 C CD2 . TYR A 1 333 ? 32.904 -29.234 -31.719 1.00 189.25 ? 360 TYR A CD2 1 ATOM 2544 C CE1 . TYR A 1 333 ? 31.584 -31.314 -32.942 1.00 191.13 ? 360 TYR A CE1 1 ATOM 2545 C CE2 . TYR A 1 333 ? 32.990 -29.388 -33.078 1.00 187.38 ? 360 TYR A CE2 1 ATOM 2546 C CZ . TYR A 1 333 ? 32.338 -30.431 -33.688 1.00 190.66 ? 360 TYR A CZ 1 ATOM 2547 O OH . TYR A 1 333 ? 32.440 -30.580 -35.050 1.00 193.59 ? 360 TYR A OH 1 ATOM 2548 N N . TYR A 1 334 ? 32.264 -26.973 -29.548 1.00 198.37 ? 361 TYR A N 1 ATOM 2549 C CA . TYR A 1 334 ? 32.474 -25.695 -30.180 1.00 199.34 ? 361 TYR A CA 1 ATOM 2550 C C . TYR A 1 334 ? 33.783 -25.738 -30.976 1.00 198.08 ? 361 TYR A C 1 ATOM 2551 O O . TYR A 1 334 ? 34.596 -26.645 -30.791 1.00 195.53 ? 361 TYR A O 1 ATOM 2552 C CB . TYR A 1 334 ? 32.496 -24.604 -29.111 1.00 194.26 ? 361 TYR A CB 1 ATOM 2553 C CG . TYR A 1 334 ? 31.218 -24.558 -28.296 1.00 190.79 ? 361 TYR A CG 1 ATOM 2554 C CD1 . TYR A 1 334 ? 31.065 -25.325 -27.139 1.00 187.62 ? 361 TYR A CD1 1 ATOM 2555 C CD2 . TYR A 1 334 ? 30.197 -23.703 -28.639 1.00 191.76 ? 361 TYR A CD2 1 ATOM 2556 C CE1 . TYR A 1 334 ? 29.910 -25.263 -26.388 1.00 188.13 ? 361 TYR A CE1 1 ATOM 2557 C CE2 . TYR A 1 334 ? 29.033 -23.630 -27.890 1.00 190.28 ? 361 TYR A CE2 1 ATOM 2558 C CZ . TYR A 1 334 ? 28.896 -24.411 -26.769 1.00 191.61 ? 361 TYR A CZ 1 ATOM 2559 O OH . TYR A 1 334 ? 27.730 -24.319 -26.047 1.00 194.95 ? 361 TYR A OH 1 ATOM 2560 N N . ILE A 1 335 ? 33.956 -24.802 -31.906 1.00 199.68 ? 362 ILE A N 1 ATOM 2561 C CA . ILE A 1 335 ? 35.205 -24.631 -32.636 1.00 195.78 ? 362 ILE A CA 1 ATOM 2562 C C . ILE A 1 335 ? 35.706 -23.173 -32.610 1.00 200.89 ? 362 ILE A C 1 ATOM 2563 O O . ILE A 1 335 ? 34.920 -22.253 -32.829 1.00 202.94 ? 362 ILE A O 1 ATOM 2564 C CB . ILE A 1 335 ? 35.099 -25.142 -34.103 1.00 184.66 ? 362 ILE A CB 1 ATOM 2565 C CG1 . ILE A 1 335 ? 34.159 -24.293 -34.947 1.00 181.10 ? 362 ILE A CG1 1 ATOM 2566 C CG2 . ILE A 1 335 ? 34.638 -26.589 -34.123 1.00 187.63 ? 362 ILE A CG2 1 ATOM 2567 C CD1 . ILE A 1 335 ? 34.267 -24.603 -36.434 1.00 171.72 ? 362 ILE A CD1 1 ATOM 2568 N N . ILE A 1 336 ? 36.973 -22.942 -32.268 1.00 199.59 ? 363 ILE A N 1 ATOM 2569 C CA . ILE A 1 336 ? 37.471 -21.574 -32.291 1.00 198.05 ? 363 ILE A CA 1 ATOM 2570 C C . ILE A 1 336 ? 38.312 -21.160 -33.523 1.00 201.39 ? 363 ILE A C 1 ATOM 2571 O O . ILE A 1 336 ? 39.287 -21.848 -33.869 1.00 199.94 ? 363 ILE A O 1 ATOM 2572 C CB . ILE A 1 336 ? 38.323 -21.371 -31.026 1.00 187.28 ? 363 ILE A CB 1 ATOM 2573 C CG1 . ILE A 1 336 ? 37.432 -21.427 -29.781 1.00 186.27 ? 363 ILE A CG1 1 ATOM 2574 C CG2 . ILE A 1 336 ? 39.203 -20.118 -31.138 1.00 191.09 ? 363 ILE A CG2 1 ATOM 2575 C CD1 . ILE A 1 336 ? 38.182 -21.301 -28.483 1.00 177.96 ? 363 ILE A CD1 1 ATOM 2576 N N . GLN A 1 337 ? 37.941 -20.077 -34.219 1.00 202.17 ? 364 GLN A N 1 ATOM 2577 C CA . GLN A 1 337 ? 38.809 -19.552 -35.283 1.00 197.13 ? 364 GLN A CA 1 ATOM 2578 C C . GLN A 1 337 ? 39.645 -18.341 -34.820 1.00 197.07 ? 364 GLN A C 1 ATOM 2579 O O . GLN A 1 337 ? 39.110 -17.422 -34.197 1.00 189.89 ? 364 GLN A O 1 ATOM 2580 C CB . GLN A 1 337 ? 38.023 -19.219 -36.562 1.00 187.78 ? 364 GLN A CB 1 ATOM 2581 C CG . GLN A 1 337 ? 37.352 -20.419 -37.249 1.00 189.84 ? 364 GLN A CG 1 ATOM 2582 C CD . GLN A 1 337 ? 36.006 -20.788 -36.674 1.00 205.23 ? 364 GLN A CD 1 ATOM 2583 O OE1 . GLN A 1 337 ? 35.832 -20.853 -35.459 1.00 212.38 ? 364 GLN A OE1 1 ATOM 2584 N NE2 . GLN A 1 337 ? 35.049 -21.071 -37.553 1.00 205.16 ? 364 GLN A NE2 1 ATOM 2585 N N . HIS A 1 338 ? 40.942 -18.327 -35.138 1.00 204.05 ? 365 HIS A N 1 ATOM 2586 C CA . HIS A 1 338 ? 41.823 -17.205 -34.756 1.00 202.72 ? 365 HIS A CA 1 ATOM 2587 C C . HIS A 1 338 ? 42.945 -16.930 -35.779 1.00 200.54 ? 365 HIS A C 1 ATOM 2588 O O . HIS A 1 338 ? 43.469 -17.859 -36.393 1.00 198.13 ? 365 HIS A O 1 ATOM 2589 C CB . HIS A 1 338 ? 42.436 -17.388 -33.362 1.00 200.67 ? 365 HIS A CB 1 ATOM 2590 C CG . HIS A 1 338 ? 43.386 -18.536 -33.239 1.00 199.08 ? 365 HIS A CG 1 ATOM 2591 N ND1 . HIS A 1 338 ? 44.752 -18.365 -33.304 1.00 190.50 ? 365 HIS A ND1 1 ATOM 2592 C CD2 . HIS A 1 338 ? 43.181 -19.855 -33.017 1.00 203.77 ? 365 HIS A CD2 1 ATOM 2593 C CE1 . HIS A 1 338 ? 45.348 -19.533 -33.150 1.00 192.42 ? 365 HIS A CE1 1 ATOM 2594 N NE2 . HIS A 1 338 ? 44.418 -20.454 -32.974 1.00 200.04 ? 365 HIS A NE2 1 ATOM 2595 N N . LYS A 1 339 ? 43.315 -15.662 -35.937 1.00 201.62 ? 366 LYS A N 1 ATOM 2596 C CA . LYS A 1 339 ? 44.462 -15.243 -36.759 1.00 203.37 ? 366 LYS A CA 1 ATOM 2597 C C . LYS A 1 339 ? 44.833 -13.852 -36.238 1.00 205.74 ? 366 LYS A C 1 ATOM 2598 O O . LYS A 1 339 ? 44.011 -13.205 -35.591 1.00 204.33 ? 366 LYS A O 1 ATOM 2599 C CB . LYS A 1 339 ? 44.167 -15.289 -38.265 1.00 196.71 ? 366 LYS A CB 1 ATOM 2600 C CG . LYS A 1 339 ? 44.829 -16.517 -38.923 1.00 197.15 ? 366 LYS A CG 1 ATOM 2601 C CD . LYS A 1 339 ? 46.259 -16.239 -39.388 1.00 193.88 ? 366 LYS A CD 1 ATOM 2602 C CE . LYS A 1 339 ? 47.014 -17.508 -39.771 1.00 186.41 ? 366 LYS A CE 1 ATOM 2603 N NZ . LYS A 1 339 ? 46.601 -18.120 -41.057 1.00 195.02 ? 366 LYS A NZ 1 ATOM 2604 N N . PRO A 1 340 ? 46.057 -13.370 -36.529 1.00 206.72 ? 367 PRO A N 1 ATOM 2605 C CA . PRO A 1 340 ? 46.340 -11.973 -36.166 1.00 198.05 ? 367 PRO A CA 1 ATOM 2606 C C . PRO A 1 340 ? 45.551 -10.799 -36.718 1.00 190.41 ? 367 PRO A C 1 ATOM 2607 O O . PRO A 1 340 ? 45.068 -10.763 -37.839 1.00 190.72 ? 367 PRO A O 1 ATOM 2608 C CB . PRO A 1 340 ? 47.796 -11.797 -36.642 1.00 195.80 ? 367 PRO A CB 1 ATOM 2609 C CG . PRO A 1 340 ? 48.362 -13.164 -36.699 1.00 202.10 ? 367 PRO A CG 1 ATOM 2610 C CD . PRO A 1 340 ? 47.238 -14.050 -37.088 1.00 205.10 ? 367 PRO A CD 1 ATOM 2611 N N . LYS A 1 341 ? 45.377 -9.848 -35.807 1.00 186.03 ? 368 LYS A N 1 ATOM 2612 C CA . LYS A 1 341 ? 44.588 -8.647 -36.014 1.00 179.97 ? 368 LYS A CA 1 ATOM 2613 C C . LYS A 1 341 ? 45.083 -7.920 -37.265 1.00 182.75 ? 368 LYS A C 1 ATOM 2614 O O . LYS A 1 341 ? 46.286 -7.690 -37.426 1.00 184.28 ? 368 LYS A O 1 ATOM 2615 C CB . LYS A 1 341 ? 44.605 -7.799 -34.740 1.00 173.82 ? 368 LYS A CB 1 ATOM 2616 C CG . LYS A 1 341 ? 45.944 -7.275 -34.301 1.00 178.90 ? 368 LYS A CG 1 ATOM 2617 C CD . LYS A 1 341 ? 45.747 -6.259 -33.194 1.00 175.78 ? 368 LYS A CD 1 ATOM 2618 C CE . LYS A 1 341 ? 45.243 -7.011 -31.954 1.00 180.10 ? 368 LYS A CE 1 ATOM 2619 N NZ . LYS A 1 341 ? 45.315 -6.247 -30.681 1.00 175.72 ? 368 LYS A NZ 1 ATOM 2620 N N . ASN A 1 342 ? 44.136 -7.592 -38.135 1.00 187.84 ? 369 ASN A N 1 ATOM 2621 C CA . ASN A 1 342 ? 44.341 -7.009 -39.460 1.00 181.44 ? 369 ASN A CA 1 ATOM 2622 C C . ASN A 1 342 ? 44.953 -7.985 -40.466 1.00 173.69 ? 369 ASN A C 1 ATOM 2623 O O . ASN A 1 342 ? 45.448 -7.566 -41.516 1.00 159.86 ? 369 ASN A O 1 ATOM 2624 C CB . ASN A 1 342 ? 45.236 -5.764 -39.372 1.00 179.72 ? 369 ASN A CB 1 ATOM 2625 C CG . ASN A 1 342 ? 44.520 -4.562 -38.789 1.00 180.99 ? 369 ASN A CG 1 ATOM 2626 O OD1 . ASN A 1 342 ? 44.056 -3.686 -39.518 1.00 176.87 ? 369 ASN A OD1 1 ATOM 2627 N ND2 . ASN A 1 342 ? 44.433 -4.512 -37.464 1.00 180.04 ? 369 ASN A ND2 1 ATOM 2628 N N . SER A 1 343 ? 44.928 -9.280 -40.157 1.00 183.20 ? 370 SER A N 1 ATOM 2629 C CA . SER A 1 343 ? 45.386 -10.274 -41.119 1.00 186.63 ? 370 SER A CA 1 ATOM 2630 C C . SER A 1 343 ? 44.228 -10.545 -42.059 1.00 200.15 ? 370 SER A C 1 ATOM 2631 O O . SER A 1 343 ? 43.069 -10.576 -41.643 1.00 202.69 ? 370 SER A O 1 ATOM 2632 C CB . SER A 1 343 ? 45.879 -11.573 -40.471 1.00 183.18 ? 370 SER A CB 1 ATOM 2633 O OG . SER A 1 343 ? 44.822 -12.269 -39.841 1.00 185.40 ? 370 SER A OG 1 ATOM 2634 N N . GLU A 1 344 ? 44.552 -10.747 -43.321 1.00 205.07 ? 371 GLU A N 1 ATOM 2635 C CA . GLU A 1 344 ? 43.571 -11.005 -44.356 1.00 205.00 ? 371 GLU A CA 1 ATOM 2636 C C . GLU A 1 344 ? 43.731 -12.457 -44.785 1.00 202.88 ? 371 GLU A C 1 ATOM 2637 O O . GLU A 1 344 ? 43.054 -12.920 -45.704 1.00 197.57 ? 371 GLU A O 1 ATOM 2638 C CB . GLU A 1 344 ? 43.716 -10.035 -45.532 1.00 201.05 ? 371 GLU A CB 1 ATOM 2639 C CG . GLU A 1 344 ? 43.835 -8.582 -45.096 1.00 193.65 ? 371 GLU A CG 1 ATOM 2640 C CD . GLU A 1 344 ? 42.956 -7.649 -45.906 1.00 195.31 ? 371 GLU A CD 1 ATOM 2641 O OE1 . GLU A 1 344 ? 43.134 -7.575 -47.138 1.00 194.85 ? 371 GLU A OE1 1 ATOM 2642 O OE2 . GLU A 1 344 ? 42.096 -6.978 -45.298 1.00 197.56 ? 371 GLU A OE2 1 ATOM 2643 N N . GLU A 1 345 ? 44.637 -13.171 -44.113 1.00 204.56 ? 372 GLU A N 1 ATOM 2644 C CA . GLU A 1 345 ? 44.830 -14.589 -44.402 1.00 202.98 ? 372 GLU A CA 1 ATOM 2645 C C . GLU A 1 345 ? 43.759 -15.422 -43.711 1.00 203.43 ? 372 GLU A C 1 ATOM 2646 O O . GLU A 1 345 ? 43.118 -14.940 -42.772 1.00 199.09 ? 372 GLU A O 1 ATOM 2647 C CB . GLU A 1 345 ? 46.188 -15.015 -43.853 1.00 200.97 ? 372 GLU A CB 1 ATOM 2648 C CG . GLU A 1 345 ? 47.363 -14.374 -44.535 1.00 193.22 ? 372 GLU A CG 1 ATOM 2649 C CD . GLU A 1 345 ? 47.810 -13.150 -43.762 1.00 190.99 ? 372 GLU A CD 1 ATOM 2650 O OE1 . GLU A 1 345 ? 47.864 -12.044 -44.346 1.00 196.69 ? 372 GLU A OE1 1 ATOM 2651 O OE2 . GLU A 1 345 ? 48.088 -13.288 -42.547 1.00 179.55 ? 372 GLU A OE2 1 ATOM 2652 N N . PRO A 1 346 ? 43.536 -16.671 -44.174 1.00 205.16 ? 373 PRO A N 1 ATOM 2653 C CA . PRO A 1 346 ? 42.483 -17.374 -43.431 1.00 206.81 ? 373 PRO A CA 1 ATOM 2654 C C . PRO A 1 346 ? 42.742 -17.649 -41.948 1.00 207.66 ? 373 PRO A C 1 ATOM 2655 O O . PRO A 1 346 ? 43.875 -17.894 -41.534 1.00 210.75 ? 373 PRO A O 1 ATOM 2656 C CB . PRO A 1 346 ? 42.373 -18.701 -44.182 1.00 202.55 ? 373 PRO A CB 1 ATOM 2657 C CG . PRO A 1 346 ? 43.752 -18.920 -44.755 1.00 197.92 ? 373 PRO A CG 1 ATOM 2658 C CD . PRO A 1 346 ? 44.215 -17.542 -45.152 1.00 196.64 ? 373 PRO A CD 1 ATOM 2659 N N . TYR A 1 347 ? 41.663 -17.619 -41.178 1.00 205.63 ? 374 TYR A N 1 ATOM 2660 C CA . TYR A 1 347 ? 41.606 -17.973 -39.759 1.00 199.78 ? 374 TYR A CA 1 ATOM 2661 C C . TYR A 1 347 ? 42.087 -19.428 -39.538 1.00 200.33 ? 374 TYR A C 1 ATOM 2662 O O . TYR A 1 347 ? 41.846 -20.284 -40.395 1.00 204.21 ? 374 TYR A O 1 ATOM 2663 C CB . TYR A 1 347 ? 40.227 -17.598 -39.208 1.00 196.03 ? 374 TYR A CB 1 ATOM 2664 C CG . TYR A 1 347 ? 40.215 -16.072 -39.084 1.00 190.06 ? 374 TYR A CG 1 ATOM 2665 C CD1 . TYR A 1 347 ? 40.232 -15.259 -40.217 1.00 185.57 ? 374 TYR A CD1 1 ATOM 2666 C CD2 . TYR A 1 347 ? 40.298 -15.448 -37.843 1.00 186.96 ? 374 TYR A CD2 1 ATOM 2667 C CE1 . TYR A 1 347 ? 40.274 -13.878 -40.122 1.00 173.52 ? 374 TYR A CE1 1 ATOM 2668 C CE2 . TYR A 1 347 ? 40.341 -14.058 -37.739 1.00 179.86 ? 374 TYR A CE2 1 ATOM 2669 C CZ . TYR A 1 347 ? 40.326 -13.282 -38.883 1.00 167.91 ? 374 TYR A CZ 1 ATOM 2670 O OH . TYR A 1 347 ? 40.375 -11.908 -38.795 1.00 152.63 ? 374 TYR A OH 1 ATOM 2671 N N . LYS A 1 348 ? 42.764 -19.721 -38.427 1.00 194.78 ? 375 LYS A N 1 ATOM 2672 C CA . LYS A 1 348 ? 42.923 -21.124 -38.007 1.00 191.78 ? 375 LYS A CA 1 ATOM 2673 C C . LYS A 1 348 ? 41.686 -21.667 -37.302 1.00 190.22 ? 375 LYS A C 1 ATOM 2674 O O . LYS A 1 348 ? 40.897 -20.926 -36.799 1.00 191.90 ? 375 LYS A O 1 ATOM 2675 C CB . LYS A 1 348 ? 44.096 -21.270 -37.040 1.00 187.51 ? 375 LYS A CB 1 ATOM 2676 C CG . LYS A 1 348 ? 45.286 -20.393 -37.319 1.00 186.72 ? 375 LYS A CG 1 ATOM 2677 C CD . LYS A 1 348 ? 46.130 -20.977 -38.421 1.00 185.29 ? 375 LYS A CD 1 ATOM 2678 C CE . LYS A 1 348 ? 47.584 -20.601 -38.248 1.00 165.42 ? 375 LYS A CE 1 ATOM 2679 N NZ . LYS A 1 348 ? 48.341 -20.886 -39.494 1.00 122.98 ? 375 LYS A NZ 1 ATOM 2680 N N . GLU A 1 349 ? 41.489 -22.972 -37.278 1.00 188.54 ? 376 GLU A N 1 ATOM 2681 C CA . GLU A 1 349 ? 40.270 -23.521 -36.733 1.00 193.28 ? 376 GLU A CA 1 ATOM 2682 C C . GLU A 1 349 ? 40.711 -24.594 -35.717 1.00 194.71 ? 376 GLU A C 1 ATOM 2683 O O . GLU A 1 349 ? 41.587 -25.437 -36.012 1.00 195.47 ? 376 GLU A O 1 ATOM 2684 C CB . GLU A 1 349 ? 39.407 -24.074 -37.851 1.00 204.31 ? 376 GLU A CB 1 ATOM 2685 C CG . GLU A 1 349 ? 38.539 -25.268 -37.544 1.00 206.93 ? 376 GLU A CG 1 ATOM 2686 C CD . GLU A 1 349 ? 37.901 -25.869 -38.812 1.00 193.37 ? 376 GLU A CD 1 ATOM 2687 O OE1 . GLU A 1 349 ? 38.047 -25.234 -39.892 1.00 200.58 ? 376 GLU A OE1 1 ATOM 2688 O OE2 . GLU A 1 349 ? 37.105 -26.841 -38.715 1.00 169.62 ? 376 GLU A OE2 1 ATOM 2689 N N . ILE A 1 350 ? 40.130 -24.554 -34.517 1.00 194.09 ? 377 ILE A N 1 ATOM 2690 C CA . ILE A 1 350 ? 40.264 -25.566 -33.464 1.00 196.29 ? 377 ILE A CA 1 ATOM 2691 C C . ILE A 1 350 ? 39.051 -26.470 -33.199 1.00 201.13 ? 377 ILE A C 1 ATOM 2692 O O . ILE A 1 350 ? 38.010 -25.976 -32.760 1.00 198.64 ? 377 ILE A O 1 ATOM 2693 C CB . ILE A 1 350 ? 40.624 -24.879 -32.141 1.00 189.27 ? 377 ILE A CB 1 ATOM 2694 C CG1 . ILE A 1 350 ? 41.885 -24.025 -32.313 1.00 183.96 ? 377 ILE A CG1 1 ATOM 2695 C CG2 . ILE A 1 350 ? 40.792 -25.890 -31.016 1.00 191.40 ? 377 ILE A CG2 1 ATOM 2696 C CD1 . ILE A 1 350 ? 42.179 -23.108 -31.142 1.00 179.12 ? 377 ILE A CD1 1 ATOM 2697 N N . ASP A 1 351 ? 39.153 -27.771 -33.446 1.00 204.19 ? 378 ASP A N 1 ATOM 2698 C CA . ASP A 1 351 ? 37.972 -28.619 -33.319 1.00 205.67 ? 378 ASP A CA 1 ATOM 2699 C C . ASP A 1 351 ? 37.747 -29.147 -31.891 1.00 206.96 ? 378 ASP A C 1 ATOM 2700 O O . ASP A 1 351 ? 38.669 -29.217 -31.074 1.00 205.43 ? 378 ASP A O 1 ATOM 2701 C CB . ASP A 1 351 ? 38.062 -29.806 -34.279 1.00 205.95 ? 378 ASP A CB 1 ATOM 2702 C CG . ASP A 1 351 ? 36.710 -30.443 -34.533 1.00 216.41 ? 378 ASP A CG 1 ATOM 2703 O OD1 . ASP A 1 351 ? 35.695 -29.766 -34.279 1.00 213.43 ? 378 ASP A OD1 1 ATOM 2704 O OD2 . ASP A 1 351 ? 36.658 -31.614 -34.962 1.00 228.43 ? 378 ASP A OD2 1 ATOM 2705 N N . GLY A 1 352 ? 36.498 -29.511 -31.617 1.00 204.81 ? 379 GLY A N 1 ATOM 2706 C CA . GLY A 1 352 ? 36.115 -30.286 -30.449 1.00 198.24 ? 379 GLY A CA 1 ATOM 2707 C C . GLY A 1 352 ? 36.229 -29.780 -29.019 1.00 188.40 ? 379 GLY A C 1 ATOM 2708 O O . GLY A 1 352 ? 36.743 -30.501 -28.165 1.00 180.62 ? 379 GLY A O 1 ATOM 2709 N N . ILE A 1 353 ? 35.764 -28.567 -28.731 1.00 186.98 ? 380 ILE A N 1 ATOM 2710 C CA . ILE A 1 353 ? 35.796 -28.103 -27.344 1.00 186.23 ? 380 ILE A CA 1 ATOM 2711 C C . ILE A 1 353 ? 34.439 -28.375 -26.701 1.00 188.71 ? 380 ILE A C 1 ATOM 2712 O O . ILE A 1 353 ? 33.428 -27.782 -27.079 1.00 188.82 ? 380 ILE A O 1 ATOM 2713 C CB . ILE A 1 353 ? 36.147 -26.602 -27.215 1.00 183.37 ? 380 ILE A CB 1 ATOM 2714 C CG1 . ILE A 1 353 ? 37.605 -26.348 -27.605 1.00 184.35 ? 380 ILE A CG1 1 ATOM 2715 C CG2 . ILE A 1 353 ? 35.978 -26.141 -25.775 1.00 181.06 ? 380 ILE A CG2 1 ATOM 2716 C CD1 . ILE A 1 353 ? 37.863 -26.286 -29.089 1.00 184.98 ? 380 ILE A CD1 1 ATOM 2717 N N . ALA A 1 354 ? 34.428 -29.285 -25.732 1.00 190.76 ? 381 ALA A N 1 ATOM 2718 C CA . ALA A 1 354 ? 33.181 -29.811 -25.182 1.00 190.55 ? 381 ALA A CA 1 ATOM 2719 C C . ALA A 1 354 ? 32.717 -29.002 -23.976 1.00 194.92 ? 381 ALA A C 1 ATOM 2720 O O . ALA A 1 354 ? 31.787 -29.400 -23.274 1.00 200.01 ? 381 ALA A O 1 ATOM 2721 C CB . ALA A 1 354 ? 33.346 -31.275 -24.804 1.00 183.26 ? 381 ALA A CB 1 ATOM 2722 N N . THR A 1 355 ? 33.355 -27.859 -23.738 1.00 188.78 ? 382 THR A N 1 ATOM 2723 C CA . THR A 1 355 ? 32.951 -27.011 -22.625 1.00 185.66 ? 382 THR A CA 1 ATOM 2724 C C . THR A 1 355 ? 32.884 -25.530 -22.968 1.00 187.53 ? 382 THR A C 1 ATOM 2725 O O . THR A 1 355 ? 33.192 -25.113 -24.086 1.00 178.15 ? 382 THR A O 1 ATOM 2726 C CB . THR A 1 355 ? 33.914 -27.177 -21.431 1.00 173.90 ? 382 THR A CB 1 ATOM 2727 O OG1 . THR A 1 355 ? 35.268 -27.157 -21.901 1.00 168.63 ? 382 THR A OG1 1 ATOM 2728 C CG2 . THR A 1 355 ? 33.653 -28.487 -20.702 1.00 159.51 ? 382 THR A CG2 1 ATOM 2729 N N . THR A 1 356 ? 32.467 -24.745 -21.982 1.00 197.06 ? 383 THR A N 1 ATOM 2730 C CA . THR A 1 356 ? 32.333 -23.305 -22.139 1.00 193.32 ? 383 THR A CA 1 ATOM 2731 C C . THR A 1 356 ? 33.540 -22.552 -21.587 1.00 194.38 ? 383 THR A C 1 ATOM 2732 O O . THR A 1 356 ? 33.460 -21.362 -21.294 1.00 194.38 ? 383 THR A O 1 ATOM 2733 C CB . THR A 1 356 ? 31.068 -22.803 -21.433 1.00 194.58 ? 383 THR A CB 1 ATOM 2734 O OG1 . THR A 1 356 ? 31.087 -23.208 -20.057 1.00 203.31 ? 383 THR A OG1 1 ATOM 2735 C CG2 . THR A 1 356 ? 29.836 -23.367 -22.107 1.00 184.80 ? 383 THR A CG2 1 ATOM 2736 N N . ARG A 1 357 ? 34.659 -23.250 -21.441 1.00 194.30 ? 384 ARG A N 1 ATOM 2737 C CA . ARG A 1 357 ? 35.906 -22.606 -21.055 1.00 189.64 ? 384 ARG A CA 1 ATOM 2738 C C . ARG A 1 357 ? 37.055 -23.327 -21.749 1.00 187.51 ? 384 ARG A C 1 ATOM 2739 O O . ARG A 1 357 ? 37.050 -24.554 -21.843 1.00 187.38 ? 384 ARG A O 1 ATOM 2740 C CB . ARG A 1 357 ? 36.048 -22.613 -19.530 1.00 179.61 ? 384 ARG A CB 1 ATOM 2741 C CG . ARG A 1 357 ? 37.407 -22.227 -18.976 1.00 174.96 ? 384 ARG A CG 1 ATOM 2742 C CD . ARG A 1 357 ? 37.293 -21.962 -17.481 1.00 178.20 ? 384 ARG A CD 1 ATOM 2743 N NE . ARG A 1 357 ? 36.096 -21.172 -17.193 1.00 180.97 ? 384 ARG A NE 1 ATOM 2744 C CZ . ARG A 1 357 ? 35.534 -21.048 -15.996 1.00 183.45 ? 384 ARG A CZ 1 ATOM 2745 N NH1 . ARG A 1 357 ? 36.062 -21.655 -14.943 1.00 191.73 ? 384 ARG A NH1 1 ATOM 2746 N NH2 . ARG A 1 357 ? 34.445 -20.304 -15.852 1.00 179.26 ? 384 ARG A NH2 1 ATOM 2747 N N . TYR A 1 358 ? 38.036 -22.573 -22.237 1.00 183.65 ? 385 TYR A N 1 ATOM 2748 C CA . TYR A 1 358 ? 39.150 -23.177 -22.964 1.00 179.38 ? 385 TYR A CA 1 ATOM 2749 C C . TYR A 1 358 ? 40.437 -22.352 -22.982 1.00 183.29 ? 385 TYR A C 1 ATOM 2750 O O . TYR A 1 358 ? 40.405 -21.132 -23.136 1.00 188.10 ? 385 TYR A O 1 ATOM 2751 C CB . TYR A 1 358 ? 38.713 -23.459 -24.401 1.00 179.35 ? 385 TYR A CB 1 ATOM 2752 C CG . TYR A 1 358 ? 39.710 -24.253 -25.204 1.00 180.27 ? 385 TYR A CG 1 ATOM 2753 C CD1 . TYR A 1 358 ? 39.856 -25.621 -25.014 1.00 177.19 ? 385 TYR A CD1 1 ATOM 2754 C CD2 . TYR A 1 358 ? 40.505 -23.634 -26.159 1.00 181.24 ? 385 TYR A CD2 1 ATOM 2755 C CE1 . TYR A 1 358 ? 40.769 -26.349 -25.753 1.00 178.61 ? 385 TYR A CE1 1 ATOM 2756 C CE2 . TYR A 1 358 ? 41.420 -24.351 -26.902 1.00 177.07 ? 385 TYR A CE2 1 ATOM 2757 C CZ . TYR A 1 358 ? 41.548 -25.708 -26.696 1.00 175.70 ? 385 TYR A CZ 1 ATOM 2758 O OH . TYR A 1 358 ? 42.459 -26.427 -27.434 1.00 173.77 ? 385 TYR A OH 1 ATOM 2759 N N . SER A 1 359 ? 41.567 -23.039 -22.823 1.00 183.38 ? 386 SER A N 1 ATOM 2760 C CA . SER A 1 359 ? 42.895 -22.424 -22.898 1.00 182.99 ? 386 SER A CA 1 ATOM 2761 C C . SER A 1 359 ? 43.566 -22.652 -24.261 1.00 181.78 ? 386 SER A C 1 ATOM 2762 O O . SER A 1 359 ? 43.857 -23.793 -24.622 1.00 180.52 ? 386 SER A O 1 ATOM 2763 C CB . SER A 1 359 ? 43.784 -22.973 -21.778 1.00 182.51 ? 386 SER A CB 1 ATOM 2764 O OG . SER A 1 359 ? 43.759 -24.392 -21.756 1.00 182.44 ? 386 SER A OG 1 ATOM 2765 N N . VAL A 1 360 ? 43.810 -21.580 -25.016 1.00 179.62 ? 387 VAL A N 1 ATOM 2766 C CA . VAL A 1 360 ? 44.541 -21.688 -26.285 1.00 180.81 ? 387 VAL A CA 1 ATOM 2767 C C . VAL A 1 360 ? 46.074 -21.617 -26.150 1.00 185.19 ? 387 VAL A C 1 ATOM 2768 O O . VAL A 1 360 ? 46.628 -20.591 -25.750 1.00 178.75 ? 387 VAL A O 1 ATOM 2769 C CB . VAL A 1 360 ? 44.073 -20.589 -27.291 1.00 172.13 ? 387 VAL A CB 1 ATOM 2770 C CG1 . VAL A 1 360 ? 43.991 -19.219 -26.626 1.00 173.07 ? 387 VAL A CG1 1 ATOM 2771 C CG2 . VAL A 1 360 ? 44.974 -20.550 -28.521 1.00 173.98 ? 387 VAL A CG2 1 ATOM 2772 N N . ALA A 1 361 ? 46.751 -22.721 -26.468 1.00 194.21 ? 388 ALA A N 1 ATOM 2773 C CA . ALA A 1 361 ? 48.204 -22.806 -26.312 1.00 187.90 ? 388 ALA A CA 1 ATOM 2774 C C . ALA A 1 361 ? 48.924 -22.817 -27.665 1.00 185.85 ? 388 ALA A C 1 ATOM 2775 O O . ALA A 1 361 ? 48.293 -22.726 -28.718 1.00 189.85 ? 388 ALA A O 1 ATOM 2776 C CB . ALA A 1 361 ? 48.578 -24.045 -25.507 1.00 184.39 ? 388 ALA A CB 1 ATOM 2777 N N . GLY A 1 362 ? 50.250 -22.917 -27.622 1.00 179.53 ? 389 GLY A N 1 ATOM 2778 C CA . GLY A 1 362 ? 51.084 -22.912 -28.815 1.00 184.48 ? 389 GLY A CA 1 ATOM 2779 C C . GLY A 1 362 ? 51.120 -21.598 -29.569 1.00 187.68 ? 389 GLY A C 1 ATOM 2780 O O . GLY A 1 362 ? 51.392 -21.567 -30.770 1.00 182.81 ? 389 GLY A O 1 ATOM 2781 N N . LEU A 1 363 ? 50.869 -20.508 -28.859 1.00 194.29 ? 390 LEU A N 1 ATOM 2782 C CA . LEU A 1 363 ? 50.874 -19.183 -29.458 1.00 200.66 ? 390 LEU A CA 1 ATOM 2783 C C . LEU A 1 363 ? 52.275 -18.579 -29.371 1.00 207.20 ? 390 LEU A C 1 ATOM 2784 O O . LEU A 1 363 ? 53.146 -19.146 -28.708 1.00 202.82 ? 390 LEU A O 1 ATOM 2785 C CB . LEU A 1 363 ? 49.824 -18.328 -28.741 1.00 193.06 ? 390 LEU A CB 1 ATOM 2786 C CG . LEU A 1 363 ? 49.500 -16.870 -29.027 1.00 184.76 ? 390 LEU A CG 1 ATOM 2787 C CD1 . LEU A 1 363 ? 48.000 -16.706 -29.058 1.00 190.50 ? 390 LEU A CD1 1 ATOM 2788 C CD2 . LEU A 1 363 ? 50.072 -16.055 -27.910 1.00 180.27 ? 390 LEU A CD2 1 ATOM 2789 N N . SER A 1 364 ? 52.513 -17.439 -30.015 1.00 208.58 ? 391 SER A N 1 ATOM 2790 C CA . SER A 1 364 ? 53.854 -16.878 -29.949 1.00 202.24 ? 391 SER A CA 1 ATOM 2791 C C . SER A 1 364 ? 53.773 -15.776 -28.923 1.00 200.07 ? 391 SER A C 1 ATOM 2792 O O . SER A 1 364 ? 52.760 -15.087 -28.838 1.00 202.07 ? 391 SER A O 1 ATOM 2793 C CB . SER A 1 364 ? 54.318 -16.336 -31.304 1.00 193.02 ? 391 SER A CB 1 ATOM 2794 O OG . SER A 1 364 ? 54.132 -17.286 -32.336 1.00 195.07 ? 391 SER A OG 1 ATOM 2795 N N . PRO A 1 365 ? 54.851 -15.575 -28.162 1.00 197.84 ? 392 PRO A N 1 ATOM 2796 C CA . PRO A 1 365 ? 54.773 -14.511 -27.164 1.00 197.12 ? 392 PRO A CA 1 ATOM 2797 C C . PRO A 1 365 ? 54.508 -13.126 -27.781 1.00 197.77 ? 392 PRO A C 1 ATOM 2798 O O . PRO A 1 365 ? 54.932 -12.890 -28.912 1.00 203.46 ? 392 PRO A O 1 ATOM 2799 C CB . PRO A 1 365 ? 56.128 -14.616 -26.483 1.00 196.25 ? 392 PRO A CB 1 ATOM 2800 C CG . PRO A 1 365 ? 57.030 -15.213 -27.490 1.00 196.34 ? 392 PRO A CG 1 ATOM 2801 C CD . PRO A 1 365 ? 56.180 -16.203 -28.206 1.00 195.69 ? 392 PRO A CD 1 ATOM 2802 N N . TYR A 1 366 ? 53.854 -12.240 -27.027 1.00 192.42 ? 393 TYR A N 1 ATOM 2803 C CA . TYR A 1 366 ? 53.630 -10.829 -27.380 1.00 191.81 ? 393 TYR A CA 1 ATOM 2804 C C . TYR A 1 366 ? 53.163 -10.740 -28.831 1.00 196.13 ? 393 TYR A C 1 ATOM 2805 O O . TYR A 1 366 ? 53.717 -9.975 -29.621 1.00 193.16 ? 393 TYR A O 1 ATOM 2806 C CB . TYR A 1 366 ? 54.854 -9.934 -27.167 1.00 193.15 ? 393 TYR A CB 1 ATOM 2807 C CG . TYR A 1 366 ? 54.503 -8.457 -27.297 1.00 185.72 ? 393 TYR A CG 1 ATOM 2808 C CD1 . TYR A 1 366 ? 53.477 -7.905 -26.536 1.00 179.90 ? 393 TYR A CD1 1 ATOM 2809 C CD2 . TYR A 1 366 ? 55.173 -7.628 -28.189 1.00 185.87 ? 393 TYR A CD2 1 ATOM 2810 C CE1 . TYR A 1 366 ? 53.135 -6.568 -26.648 1.00 177.77 ? 393 TYR A CE1 1 ATOM 2811 C CE2 . TYR A 1 366 ? 54.836 -6.285 -28.308 1.00 186.46 ? 393 TYR A CE2 1 ATOM 2812 C CZ . TYR A 1 366 ? 53.816 -5.763 -27.535 1.00 181.66 ? 393 TYR A CZ 1 ATOM 2813 O OH . TYR A 1 366 ? 53.479 -4.433 -27.647 1.00 180.53 ? 393 TYR A OH 1 ATOM 2814 N N . SER A 1 367 ? 52.151 -11.518 -29.194 1.00 206.00 ? 394 SER A N 1 ATOM 2815 C CA . SER A 1 367 ? 51.718 -11.530 -30.585 1.00 216.45 ? 394 SER A CA 1 ATOM 2816 C C . SER A 1 367 ? 50.224 -11.321 -30.673 1.00 217.94 ? 394 SER A C 1 ATOM 2817 O O . SER A 1 367 ? 49.461 -11.805 -29.836 1.00 215.83 ? 394 SER A O 1 ATOM 2818 C CB . SER A 1 367 ? 52.104 -12.851 -31.257 1.00 216.14 ? 394 SER A CB 1 ATOM 2819 O OG . SER A 1 367 ? 51.479 -13.950 -30.615 1.00 210.00 ? 394 SER A OG 1 ATOM 2820 N N . ASP A 1 368 ? 49.812 -10.598 -31.706 1.00 217.03 ? 395 ASP A N 1 ATOM 2821 C CA . ASP A 1 368 ? 48.412 -10.264 -31.851 1.00 209.84 ? 395 ASP A CA 1 ATOM 2822 C C . ASP A 1 368 ? 47.558 -11.266 -32.618 1.00 203.23 ? 395 ASP A C 1 ATOM 2823 O O . ASP A 1 368 ? 47.957 -11.775 -33.653 1.00 199.00 ? 395 ASP A O 1 ATOM 2824 C CB . ASP A 1 368 ? 48.311 -8.901 -32.532 1.00 211.65 ? 395 ASP A CB 1 ATOM 2825 C CG . ASP A 1 368 ? 48.925 -7.791 -31.705 1.00 207.15 ? 395 ASP A CG 1 ATOM 2826 O OD1 . ASP A 1 368 ? 48.952 -7.927 -30.467 1.00 206.05 ? 395 ASP A OD1 1 ATOM 2827 O OD2 . ASP A 1 368 ? 49.387 -6.790 -32.291 1.00 202.68 ? 395 ASP A OD2 1 ATOM 2828 N N . TYR A 1 369 ? 46.422 -11.590 -32.016 1.00 202.61 ? 396 TYR A N 1 ATOM 2829 C CA . TYR A 1 369 ? 45.416 -12.535 -32.506 1.00 207.73 ? 396 TYR A CA 1 ATOM 2830 C C . TYR A 1 369 ? 44.005 -11.959 -32.382 1.00 205.34 ? 396 TYR A C 1 ATOM 2831 O O . TYR A 1 369 ? 43.705 -11.192 -31.467 1.00 198.06 ? 396 TYR A O 1 ATOM 2832 C CB . TYR A 1 369 ? 45.579 -13.929 -31.896 1.00 212.15 ? 396 TYR A CB 1 ATOM 2833 C CG . TYR A 1 369 ? 46.821 -14.617 -32.441 1.00 208.71 ? 396 TYR A CG 1 ATOM 2834 C CD1 . TYR A 1 369 ? 48.003 -14.699 -31.724 1.00 206.94 ? 396 TYR A CD1 1 ATOM 2835 C CD2 . TYR A 1 369 ? 46.782 -15.202 -33.705 1.00 205.68 ? 396 TYR A CD2 1 ATOM 2836 C CE1 . TYR A 1 369 ? 49.119 -15.341 -32.262 1.00 197.44 ? 396 TYR A CE1 1 ATOM 2837 C CE2 . TYR A 1 369 ? 47.879 -15.840 -34.242 1.00 204.00 ? 396 TYR A CE2 1 ATOM 2838 C CZ . TYR A 1 369 ? 49.045 -15.908 -33.521 1.00 198.83 ? 396 TYR A CZ 1 ATOM 2839 O OH . TYR A 1 369 ? 50.136 -16.545 -34.069 1.00 195.20 ? 396 TYR A OH 1 ATOM 2840 N N . GLU A 1 370 ? 43.156 -12.340 -33.326 1.00 206.22 ? 397 GLU A N 1 ATOM 2841 C CA . GLU A 1 370 ? 41.754 -11.951 -33.363 1.00 204.20 ? 397 GLU A CA 1 ATOM 2842 C C . GLU A 1 370 ? 40.902 -13.203 -33.172 1.00 207.93 ? 397 GLU A C 1 ATOM 2843 O O . GLU A 1 370 ? 41.167 -14.231 -33.792 1.00 207.57 ? 397 GLU A O 1 ATOM 2844 C CB . GLU A 1 370 ? 41.452 -11.246 -34.693 1.00 199.21 ? 397 GLU A CB 1 ATOM 2845 C CG . GLU A 1 370 ? 40.048 -11.416 -35.226 1.00 199.36 ? 397 GLU A CG 1 ATOM 2846 C CD . GLU A 1 370 ? 39.009 -10.815 -34.317 1.00 196.39 ? 397 GLU A CD 1 ATOM 2847 O OE1 . GLU A 1 370 ? 39.239 -9.704 -33.790 1.00 198.45 ? 397 GLU A OE1 1 ATOM 2848 O OE2 . GLU A 1 370 ? 37.968 -11.467 -34.125 1.00 194.69 ? 397 GLU A OE2 1 ATOM 2849 N N . PHE A 1 371 ? 39.872 -13.121 -32.327 1.00 209.86 ? 398 PHE A N 1 ATOM 2850 C CA . PHE A 1 371 ? 39.055 -14.302 -32.060 1.00 210.31 ? 398 PHE A CA 1 ATOM 2851 C C . PHE A 1 371 ? 37.559 -14.100 -32.221 1.00 207.66 ? 398 PHE A C 1 ATOM 2852 O O . PHE A 1 371 ? 37.019 -13.042 -31.897 1.00 204.80 ? 398 PHE A O 1 ATOM 2853 C CB . PHE A 1 371 ? 39.213 -14.735 -30.594 1.00 212.58 ? 398 PHE A CB 1 ATOM 2854 C CG . PHE A 1 371 ? 40.598 -15.124 -30.185 1.00 213.56 ? 398 PHE A CG 1 ATOM 2855 C CD1 . PHE A 1 371 ? 41.051 -16.420 -30.334 1.00 209.36 ? 398 PHE A CD1 1 ATOM 2856 C CD2 . PHE A 1 371 ? 41.423 -14.194 -29.573 1.00 211.18 ? 398 PHE A CD2 1 ATOM 2857 C CE1 . PHE A 1 371 ? 42.322 -16.771 -29.920 1.00 203.46 ? 398 PHE A CE1 1 ATOM 2858 C CE2 . PHE A 1 371 ? 42.690 -14.537 -29.158 1.00 208.50 ? 398 PHE A CE2 1 ATOM 2859 C CZ . PHE A 1 371 ? 43.143 -15.827 -29.332 1.00 206.49 ? 398 PHE A CZ 1 ATOM 2860 N N . ARG A 1 372 ? 36.896 -15.133 -32.728 1.00 205.72 ? 399 ARG A N 1 ATOM 2861 C CA . ARG A 1 372 ? 35.451 -15.262 -32.628 1.00 200.06 ? 399 ARG A CA 1 ATOM 2862 C C . ARG A 1 372 ? 35.161 -16.710 -32.226 1.00 200.73 ? 399 ARG A C 1 ATOM 2863 O O . ARG A 1 372 ? 36.028 -17.566 -32.399 1.00 197.85 ? 399 ARG A O 1 ATOM 2864 C CB . ARG A 1 372 ? 34.818 -14.868 -33.959 1.00 189.40 ? 399 ARG A CB 1 ATOM 2865 C CG . ARG A 1 372 ? 35.828 -14.966 -35.095 1.00 185.17 ? 399 ARG A CG 1 ATOM 2866 C CD . ARG A 1 372 ? 35.277 -14.565 -36.443 1.00 179.25 ? 399 ARG A CD 1 ATOM 2867 N NE . ARG A 1 372 ? 35.950 -13.344 -36.887 1.00 177.33 ? 399 ARG A NE 1 ATOM 2868 C CZ . ARG A 1 372 ? 35.919 -12.865 -38.125 1.00 168.71 ? 399 ARG A CZ 1 ATOM 2869 N NH1 . ARG A 1 372 ? 35.239 -13.497 -39.070 1.00 162.59 ? 399 ARG A NH1 1 ATOM 2870 N NH2 . ARG A 1 372 ? 36.584 -11.756 -38.420 1.00 160.07 ? 399 ARG A NH2 1 ATOM 2871 N N . VAL A 1 373 ? 33.975 -17.014 -31.701 1.00 202.91 ? 400 VAL A N 1 ATOM 2872 C CA . VAL A 1 373 ? 33.674 -18.419 -31.424 1.00 203.03 ? 400 VAL A CA 1 ATOM 2873 C C . VAL A 1 373 ? 32.384 -18.844 -32.137 1.00 202.90 ? 400 VAL A C 1 ATOM 2874 O O . VAL A 1 373 ? 31.424 -18.079 -32.198 1.00 205.87 ? 400 VAL A O 1 ATOM 2875 C CB . VAL A 1 373 ? 33.556 -18.690 -29.904 1.00 194.19 ? 400 VAL A CB 1 ATOM 2876 C CG1 . VAL A 1 373 ? 33.485 -20.188 -29.640 1.00 184.81 ? 400 VAL A CG1 1 ATOM 2877 C CG2 . VAL A 1 373 ? 34.748 -18.100 -29.162 1.00 187.68 ? 400 VAL A CG2 1 ATOM 2878 N N . VAL A 1 374 ? 32.385 -20.050 -32.697 1.00 198.73 ? 401 VAL A N 1 ATOM 2879 C CA . VAL A 1 374 ? 31.216 -20.640 -33.357 1.00 197.66 ? 401 VAL A CA 1 ATOM 2880 C C . VAL A 1 374 ? 30.841 -21.961 -32.674 1.00 198.90 ? 401 VAL A C 1 ATOM 2881 O O . VAL A 1 374 ? 31.732 -22.720 -32.285 1.00 196.35 ? 401 VAL A O 1 ATOM 2882 C CB . VAL A 1 374 ? 31.433 -20.833 -34.885 1.00 192.49 ? 401 VAL A CB 1 ATOM 2883 C CG1 . VAL A 1 374 ? 32.750 -20.218 -35.326 1.00 192.88 ? 401 VAL A CG1 1 ATOM 2884 C CG2 . VAL A 1 374 ? 31.332 -22.298 -35.295 1.00 192.64 ? 401 VAL A CG2 1 ATOM 2885 N N . ALA A 1 375 ? 29.551 -22.237 -32.487 1.00 204.46 ? 402 ALA A N 1 ATOM 2886 C CA . ALA A 1 375 ? 29.191 -23.544 -31.944 1.00 203.64 ? 402 ALA A CA 1 ATOM 2887 C C . ALA A 1 375 ? 28.823 -24.493 -33.070 1.00 198.32 ? 402 ALA A C 1 ATOM 2888 O O . ALA A 1 375 ? 28.199 -24.086 -34.047 1.00 197.93 ? 402 ALA A O 1 ATOM 2889 C CB . ALA A 1 375 ? 28.021 -23.411 -30.999 1.00 199.96 ? 402 ALA A CB 1 ATOM 2890 N N . VAL A 1 376 ? 29.191 -25.764 -32.927 1.00 195.54 ? 403 VAL A N 1 ATOM 2891 C CA . VAL A 1 376 ? 28.813 -26.770 -33.915 1.00 192.95 ? 403 VAL A CA 1 ATOM 2892 C C . VAL A 1 376 ? 28.133 -28.001 -33.306 1.00 200.18 ? 403 VAL A C 1 ATOM 2893 O O . VAL A 1 376 ? 28.631 -28.570 -32.336 1.00 203.78 ? 403 VAL A O 1 ATOM 2894 C CB . VAL A 1 376 ? 30.044 -27.236 -34.734 1.00 190.22 ? 403 VAL A CB 1 ATOM 2895 C CG1 . VAL A 1 376 ? 29.645 -28.298 -35.753 1.00 183.63 ? 403 VAL A CG1 1 ATOM 2896 C CG2 . VAL A 1 376 ? 30.701 -26.053 -35.435 1.00 191.90 ? 403 VAL A CG2 1 ATOM 2897 N N . ASN A 1 377 ? 27.006 -28.413 -33.878 1.00 202.24 ? 404 ASN A N 1 ATOM 2898 C CA . ASN A 1 377 ? 26.413 -29.710 -33.555 1.00 201.54 ? 404 ASN A CA 1 ATOM 2899 C C . ASN A 1 377 ? 26.284 -30.425 -34.907 1.00 196.57 ? 404 ASN A C 1 ATOM 2900 O O . ASN A 1 377 ? 26.849 -29.963 -35.898 1.00 193.46 ? 404 ASN A O 1 ATOM 2901 C CB . ASN A 1 377 ? 25.101 -29.636 -32.749 1.00 196.69 ? 404 ASN A CB 1 ATOM 2902 C CG . ASN A 1 377 ? 23.955 -29.022 -33.500 1.00 194.81 ? 404 ASN A CG 1 ATOM 2903 O OD1 . ASN A 1 377 ? 23.745 -27.814 -33.461 1.00 189.72 ? 404 ASN A OD1 1 ATOM 2904 N ND2 . ASN A 1 377 ? 23.155 -29.868 -34.138 1.00 190.94 ? 404 ASN A ND2 1 ATOM 2905 N N . ASN A 1 378 ? 25.565 -31.539 -34.961 1.00 192.40 ? 405 ASN A N 1 ATOM 2906 C CA . ASN A 1 378 ? 25.468 -32.327 -36.194 1.00 191.30 ? 405 ASN A CA 1 ATOM 2907 C C . ASN A 1 378 ? 24.819 -31.723 -37.455 1.00 195.19 ? 405 ASN A C 1 ATOM 2908 O O . ASN A 1 378 ? 24.724 -32.414 -38.471 1.00 195.02 ? 405 ASN A O 1 ATOM 2909 C CB . ASN A 1 378 ? 24.705 -33.617 -35.877 1.00 186.38 ? 405 ASN A CB 1 ATOM 2910 C CG . ASN A 1 378 ? 25.460 -34.532 -34.938 1.00 175.46 ? 405 ASN A CG 1 ATOM 2911 O OD1 . ASN A 1 378 ? 26.651 -34.348 -34.693 1.00 175.58 ? 405 ASN A OD1 1 ATOM 2912 N ND2 . ASN A 1 378 ? 24.764 -35.527 -34.399 1.00 169.67 ? 405 ASN A ND2 1 ATOM 2913 N N . ILE A 1 379 ? 24.401 -30.460 -37.434 1.00 198.24 ? 406 ILE A N 1 ATOM 2914 C CA . ILE A 1 379 ? 23.858 -29.859 -38.660 1.00 194.32 ? 406 ILE A CA 1 ATOM 2915 C C . ILE A 1 379 ? 24.873 -28.989 -39.409 1.00 192.92 ? 406 ILE A C 1 ATOM 2916 O O . ILE A 1 379 ? 25.002 -29.097 -40.629 1.00 185.58 ? 406 ILE A O 1 ATOM 2917 C CB . ILE A 1 379 ? 22.589 -29.006 -38.397 1.00 195.21 ? 406 ILE A CB 1 ATOM 2918 C CG1 . ILE A 1 379 ? 22.444 -28.660 -36.922 1.00 191.69 ? 406 ILE A CG1 1 ATOM 2919 C CG2 . ILE A 1 379 ? 21.353 -29.728 -38.878 1.00 194.21 ? 406 ILE A CG2 1 ATOM 2920 C CD1 . ILE A 1 379 ? 23.386 -27.600 -36.478 1.00 188.07 ? 406 ILE A CD1 1 ATOM 2921 N N . GLY A 1 380 ? 25.590 -28.131 -38.690 1.00 197.36 ? 407 GLY A N 1 ATOM 2922 C CA . GLY A 1 380 ? 26.567 -27.259 -39.318 1.00 193.06 ? 407 GLY A CA 1 ATOM 2923 C C . GLY A 1 380 ? 27.071 -26.136 -38.430 1.00 186.95 ? 407 GLY A C 1 ATOM 2924 O O . GLY A 1 380 ? 26.484 -25.840 -37.389 1.00 184.39 ? 407 GLY A O 1 ATOM 2925 N N . ARG A 1 381 ? 28.170 -25.514 -38.848 1.00 183.54 ? 408 ARG A N 1 ATOM 2926 C CA . ARG A 1 381 ? 28.742 -24.380 -38.126 1.00 182.89 ? 408 ARG A CA 1 ATOM 2927 C C . ARG A 1 381 ? 27.864 -23.136 -38.232 1.00 181.49 ? 408 ARG A C 1 ATOM 2928 O O . ARG A 1 381 ? 27.488 -22.697 -39.319 1.00 179.91 ? 408 ARG A O 1 ATOM 2929 C CB . ARG A 1 381 ? 30.167 -24.043 -38.582 1.00 189.39 ? 408 ARG A CB 1 ATOM 2930 C CG . ARG A 1 381 ? 30.334 -23.615 -40.022 1.00 194.78 ? 408 ARG A CG 1 ATOM 2931 C CD . ARG A 1 381 ? 31.790 -23.269 -40.289 1.00 193.44 ? 408 ARG A CD 1 ATOM 2932 N NE . ARG A 1 381 ? 32.165 -22.062 -39.551 1.00 188.28 ? 408 ARG A NE 1 ATOM 2933 C CZ . ARG A 1 381 ? 31.874 -20.825 -39.948 1.00 188.64 ? 408 ARG A CZ 1 ATOM 2934 N NH1 . ARG A 1 381 ? 31.213 -20.631 -41.081 1.00 191.14 ? 408 ARG A NH1 1 ATOM 2935 N NH2 . ARG A 1 381 ? 32.239 -19.783 -39.213 1.00 182.69 ? 408 ARG A NH2 1 ATOM 2936 N N . GLY A 1 382 ? 27.529 -22.595 -37.070 1.00 185.73 ? 409 GLY A N 1 ATOM 2937 C CA . GLY A 1 382 ? 26.732 -21.393 -36.959 1.00 188.36 ? 409 GLY A CA 1 ATOM 2938 C C . GLY A 1 382 ? 27.603 -20.167 -37.152 1.00 193.93 ? 409 GLY A C 1 ATOM 2939 O O . GLY A 1 382 ? 28.808 -20.282 -37.388 1.00 192.13 ? 409 GLY A O 1 ATOM 2940 N N . PRO A 1 383 ? 26.993 -18.982 -37.050 1.00 199.22 ? 410 PRO A N 1 ATOM 2941 C CA . PRO A 1 383 ? 27.711 -17.708 -37.120 1.00 200.25 ? 410 PRO A CA 1 ATOM 2942 C C . PRO A 1 383 ? 28.638 -17.520 -35.933 1.00 196.98 ? 410 PRO A C 1 ATOM 2943 O O . PRO A 1 383 ? 28.439 -18.082 -34.857 1.00 195.17 ? 410 PRO A O 1 ATOM 2944 C CB . PRO A 1 383 ? 26.595 -16.652 -37.093 1.00 193.74 ? 410 PRO A CB 1 ATOM 2945 C CG . PRO A 1 383 ? 25.311 -17.393 -36.929 1.00 194.56 ? 410 PRO A CG 1 ATOM 2946 C CD . PRO A 1 383 ? 25.551 -18.815 -37.287 1.00 192.00 ? 410 PRO A CD 1 ATOM 2947 N N . ALA A 1 384 ? 29.688 -16.750 -36.176 1.00 193.30 ? 411 ALA A N 1 ATOM 2948 C CA . ALA A 1 384 ? 30.698 -16.433 -35.184 1.00 190.47 ? 411 ALA A CA 1 ATOM 2949 C C . ALA A 1 384 ? 30.121 -15.548 -34.090 1.00 190.37 ? 411 ALA A C 1 ATOM 2950 O O . ALA A 1 384 ? 29.181 -14.787 -34.312 1.00 187.56 ? 411 ALA A O 1 ATOM 2951 C CB . ALA A 1 384 ? 31.891 -15.755 -35.842 1.00 183.71 ? 411 ALA A CB 1 ATOM 2952 N N . SER A 1 385 ? 30.695 -15.679 -32.897 1.00 192.70 ? 412 SER A N 1 ATOM 2953 C CA . SER A 1 385 ? 30.409 -14.774 -31.792 1.00 186.84 ? 412 SER A CA 1 ATOM 2954 C C . SER A 1 385 ? 30.805 -13.379 -32.239 1.00 187.39 ? 412 SER A C 1 ATOM 2955 O O . SER A 1 385 ? 31.456 -13.227 -33.275 1.00 186.19 ? 412 SER A O 1 ATOM 2956 C CB . SER A 1 385 ? 31.171 -15.183 -30.529 1.00 185.23 ? 412 SER A CB 1 ATOM 2957 O OG . SER A 1 385 ? 32.562 -14.937 -30.668 1.00 181.54 ? 412 SER A OG 1 ATOM 2958 N N . GLU A 1 386 ? 30.459 -12.353 -31.469 1.00 187.28 ? 413 GLU A N 1 ATOM 2959 C CA . GLU A 1 386 ? 31.036 -11.067 -31.803 1.00 192.29 ? 413 GLU A CA 1 ATOM 2960 C C . GLU A 1 386 ? 32.525 -11.148 -31.566 1.00 196.72 ? 413 GLU A C 1 ATOM 2961 O O . GLU A 1 386 ? 32.979 -11.886 -30.688 1.00 197.98 ? 413 GLU A O 1 ATOM 2962 C CB . GLU A 1 386 ? 30.408 -9.969 -30.939 1.00 181.65 ? 413 GLU A CB 1 ATOM 2963 C CG . GLU A 1 386 ? 29.203 -10.451 -30.129 1.00 168.11 ? 413 GLU A CG 1 ATOM 2964 C CD . GLU A 1 386 ? 29.340 -10.196 -28.636 1.00 154.07 ? 413 GLU A CD 1 ATOM 2965 O OE1 . GLU A 1 386 ? 30.037 -10.976 -27.952 1.00 156.90 ? 413 GLU A OE1 1 ATOM 2966 O OE2 . GLU A 1 386 ? 28.741 -9.214 -28.149 1.00 149.22 ? 413 GLU A OE2 1 ATOM 2967 N N . PRO A 1 387 ? 33.300 -10.376 -32.341 1.00 195.79 ? 414 PRO A N 1 ATOM 2968 C CA . PRO A 1 387 ? 34.701 -10.742 -32.138 1.00 193.08 ? 414 PRO A CA 1 ATOM 2969 C C . PRO A 1 387 ? 35.321 -10.060 -30.926 1.00 190.27 ? 414 PRO A C 1 ATOM 2970 O O . PRO A 1 387 ? 34.767 -9.076 -30.436 1.00 185.11 ? 414 PRO A O 1 ATOM 2971 C CB . PRO A 1 387 ? 35.364 -10.271 -33.435 1.00 187.96 ? 414 PRO A CB 1 ATOM 2972 C CG . PRO A 1 387 ? 34.254 -10.229 -34.447 1.00 183.59 ? 414 PRO A CG 1 ATOM 2973 C CD . PRO A 1 387 ? 33.058 -9.781 -33.665 1.00 190.18 ? 414 PRO A CD 1 ATOM 2974 N N . VAL A 1 388 ? 36.447 -10.581 -30.447 1.00 193.06 ? 415 VAL A N 1 ATOM 2975 C CA . VAL A 1 388 ? 37.251 -9.899 -29.439 1.00 193.39 ? 415 VAL A CA 1 ATOM 2976 C C . VAL A 1 388 ? 38.728 -9.706 -29.822 1.00 196.45 ? 415 VAL A C 1 ATOM 2977 O O . VAL A 1 388 ? 39.361 -10.626 -30.346 1.00 195.57 ? 415 VAL A O 1 ATOM 2978 C CB . VAL A 1 388 ? 37.159 -10.636 -28.075 1.00 195.34 ? 415 VAL A CB 1 ATOM 2979 C CG1 . VAL A 1 388 ? 35.719 -10.646 -27.565 1.00 196.07 ? 415 VAL A CG1 1 ATOM 2980 C CG2 . VAL A 1 388 ? 37.733 -12.050 -28.165 1.00 199.82 ? 415 VAL A CG2 1 ATOM 2981 N N . LEU A 1 389 ? 39.281 -8.519 -29.591 1.00 199.38 ? 416 LEU A N 1 ATOM 2982 C CA . LEU A 1 389 ? 40.716 -8.322 -29.800 1.00 203.02 ? 416 LEU A CA 1 ATOM 2983 C C . LEU A 1 389 ? 41.424 -8.274 -28.447 1.00 204.23 ? 416 LEU A C 1 ATOM 2984 O O . LEU A 1 389 ? 40.891 -7.720 -27.485 1.00 196.82 ? 416 LEU A O 1 ATOM 2985 C CB . LEU A 1 389 ? 41.020 -7.055 -30.608 1.00 202.62 ? 416 LEU A CB 1 ATOM 2986 C CG . LEU A 1 389 ? 40.644 -7.040 -32.093 1.00 195.42 ? 416 LEU A CG 1 ATOM 2987 C CD1 . LEU A 1 389 ? 39.209 -6.590 -32.311 1.00 184.54 ? 416 LEU A CD1 1 ATOM 2988 C CD2 . LEU A 1 389 ? 41.620 -6.174 -32.885 1.00 197.70 ? 416 LEU A CD2 1 ATOM 2989 N N . THR A 1 390 ? 42.617 -8.855 -28.372 1.00 209.91 ? 417 THR A N 1 ATOM 2990 C CA . THR A 1 390 ? 43.368 -8.893 -27.119 1.00 206.54 ? 417 THR A CA 1 ATOM 2991 C C . THR A 1 390 ? 44.857 -9.109 -27.397 1.00 201.99 ? 417 THR A C 1 ATOM 2992 O O . THR A 1 390 ? 45.236 -9.958 -28.208 1.00 195.91 ? 417 THR A O 1 ATOM 2993 C CB . THR A 1 390 ? 42.828 -9.984 -26.147 1.00 195.18 ? 417 THR A CB 1 ATOM 2994 O OG1 . THR A 1 390 ? 43.459 -9.849 -24.867 1.00 177.71 ? 417 THR A OG1 1 ATOM 2995 C CG2 . THR A 1 390 ? 43.050 -11.395 -26.689 1.00 197.90 ? 417 THR A CG2 1 ATOM 2996 N N . GLN A 1 391 ? 45.703 -8.311 -26.752 1.00 195.89 ? 418 GLN A N 1 ATOM 2997 C CA . GLN A 1 391 ? 47.135 -8.378 -27.012 1.00 190.15 ? 418 GLN A CA 1 ATOM 2998 C C . GLN A 1 391 ? 47.767 -9.241 -25.927 1.00 188.23 ? 418 GLN A C 1 ATOM 2999 O O . GLN A 1 391 ? 47.496 -9.060 -24.738 1.00 177.05 ? 418 GLN A O 1 ATOM 3000 C CB . GLN A 1 391 ? 47.756 -6.979 -27.064 1.00 191.93 ? 418 GLN A CB 1 ATOM 3001 C CG . GLN A 1 391 ? 49.196 -6.961 -27.553 1.00 194.76 ? 418 GLN A CG 1 ATOM 3002 C CD . GLN A 1 391 ? 49.803 -5.572 -27.539 1.00 193.86 ? 418 GLN A CD 1 ATOM 3003 O OE1 . GLN A 1 391 ? 49.395 -4.712 -26.760 1.00 191.82 ? 418 GLN A OE1 1 ATOM 3004 N NE2 . GLN A 1 391 ? 50.772 -5.342 -28.418 1.00 193.29 ? 418 GLN A NE2 1 ATOM 3005 N N . THR A 1 392 ? 48.611 -10.177 -26.344 1.00 191.20 ? 419 THR A N 1 ATOM 3006 C CA . THR A 1 392 ? 49.372 -10.997 -25.408 1.00 190.35 ? 419 THR A CA 1 ATOM 3007 C C . THR A 1 392 ? 50.471 -10.232 -24.692 1.00 188.11 ? 419 THR A C 1 ATOM 3008 O O . THR A 1 392 ? 51.595 -10.123 -25.170 1.00 187.83 ? 419 THR A O 1 ATOM 3009 C CB . THR A 1 392 ? 49.982 -12.207 -26.122 1.00 187.60 ? 419 THR A CB 1 ATOM 3010 O OG1 . THR A 1 392 ? 50.543 -11.790 -27.373 1.00 189.80 ? 419 THR A OG1 1 ATOM 3011 C CG2 . THR A 1 392 ? 48.902 -13.231 -26.384 1.00 186.37 ? 419 THR A CG2 1 ATOM 3012 N N . SER A 1 393 ? 50.116 -9.695 -23.534 1.00 183.93 ? 420 SER A N 1 ATOM 3013 C CA . SER A 1 393 ? 51.028 -8.887 -22.743 1.00 191.79 ? 420 SER A CA 1 ATOM 3014 C C . SER A 1 393 ? 52.193 -9.680 -22.161 1.00 196.87 ? 420 SER A C 1 ATOM 3015 O O . SER A 1 393 ? 51.998 -10.519 -21.281 1.00 193.56 ? 420 SER A O 1 ATOM 3016 C CB . SER A 1 393 ? 50.265 -8.208 -21.604 1.00 185.95 ? 420 SER A CB 1 ATOM 3017 O OG . SER A 1 393 ? 49.682 -9.172 -20.742 1.00 172.62 ? 420 SER A OG 1 ATOM 3018 N N . GLU A 1 394 ? 53.401 -9.425 -22.652 1.00 198.55 ? 421 GLU A N 1 ATOM 3019 C CA . GLU A 1 394 ? 54.573 -10.046 -22.050 1.00 197.53 ? 421 GLU A CA 1 ATOM 3020 C C . GLU A 1 394 ? 55.045 -9.248 -20.857 1.00 202.01 ? 421 GLU A C 1 ATOM 3021 O O . GLU A 1 394 ? 55.301 -8.041 -20.921 1.00 194.50 ? 421 GLU A O 1 ATOM 3022 C CB . GLU A 1 394 ? 55.699 -10.237 -23.040 1.00 190.78 ? 421 GLU A CB 1 ATOM 3023 C CG . GLU A 1 394 ? 55.489 -11.306 -24.070 1.00 192.77 ? 421 GLU A CG 1 ATOM 3024 C CD . GLU A 1 394 ? 56.756 -11.432 -24.828 1.00 200.30 ? 421 GLU A CD 1 ATOM 3025 O OE1 . GLU A 1 394 ? 57.420 -10.423 -24.857 1.00 202.10 ? 421 GLU A OE1 1 ATOM 3026 O OE2 . GLU A 1 394 ? 57.193 -12.498 -25.247 1.00 197.99 ? 421 GLU A OE2 1 ATOM 3027 N N . GLN A 1 395 ? 55.174 -9.991 -19.771 1.00 212.64 ? 422 GLN A N 1 ATOM 3028 C CA . GLN A 1 395 ? 55.787 -9.594 -18.520 1.00 212.90 ? 422 GLN A CA 1 ATOM 3029 C C . GLN A 1 395 ? 57.286 -9.253 -18.395 1.00 204.21 ? 422 GLN A C 1 ATOM 3030 O O . GLN A 1 395 ? 57.692 -8.793 -17.330 1.00 196.37 ? 422 GLN A O 1 ATOM 3031 C CB . GLN A 1 395 ? 55.473 -10.722 -17.523 1.00 214.97 ? 422 GLN A CB 1 ATOM 3032 C CG . GLN A 1 395 ? 54.073 -10.629 -16.921 1.00 214.11 ? 422 GLN A CG 1 ATOM 3033 C CD . GLN A 1 395 ? 52.982 -10.823 -17.969 1.00 212.63 ? 422 GLN A CD 1 ATOM 3034 O OE1 . GLN A 1 395 ? 53.112 -11.660 -18.866 1.00 212.54 ? 422 GLN A OE1 1 ATOM 3035 N NE2 . GLN A 1 395 ? 51.915 -10.039 -17.872 1.00 201.61 ? 422 GLN A NE2 1 ATOM 3036 N N . ALA A 1 396 ? 58.097 -9.451 -19.435 1.00 195.76 ? 423 ALA A N 1 ATOM 3037 C CA . ALA A 1 396 ? 59.446 -8.845 -19.502 1.00 185.69 ? 423 ALA A CA 1 ATOM 3038 C C . ALA A 1 396 ? 60.174 -9.186 -20.785 1.00 186.80 ? 423 ALA A C 1 ATOM 3039 O O . ALA A 1 396 ? 59.876 -10.202 -21.411 1.00 183.98 ? 423 ALA A O 1 ATOM 3040 C CB . ALA A 1 396 ? 60.307 -9.281 -18.313 1.00 180.26 ? 423 ALA A CB 1 ATOM 3041 N N . PRO A 1 397 ? 61.105 -8.310 -21.217 1.00 193.99 ? 424 PRO A N 1 ATOM 3042 C CA . PRO A 1 397 ? 61.887 -8.740 -22.381 1.00 189.45 ? 424 PRO A CA 1 ATOM 3043 C C . PRO A 1 397 ? 62.595 -10.092 -22.141 1.00 186.16 ? 424 PRO A C 1 ATOM 3044 O O . PRO A 1 397 ? 62.985 -10.391 -21.012 1.00 185.66 ? 424 PRO A O 1 ATOM 3045 C CB . PRO A 1 397 ? 62.897 -7.601 -22.572 1.00 187.55 ? 424 PRO A CB 1 ATOM 3046 C CG . PRO A 1 397 ? 62.215 -6.402 -21.979 1.00 193.04 ? 424 PRO A CG 1 ATOM 3047 C CD . PRO A 1 397 ? 61.391 -6.917 -20.837 1.00 196.34 ? 424 PRO A CD 1 ATOM 3048 N N . SER A 1 398 ? 62.750 -10.897 -23.189 1.00 186.98 ? 425 SER A N 1 ATOM 3049 C CA . SER A 1 398 ? 63.408 -12.192 -23.087 1.00 190.66 ? 425 SER A CA 1 ATOM 3050 C C . SER A 1 398 ? 64.709 -12.276 -23.880 1.00 189.55 ? 425 SER A C 1 ATOM 3051 O O . SER A 1 398 ? 65.233 -13.372 -24.102 1.00 191.40 ? 425 SER A O 1 ATOM 3052 C CB . SER A 1 398 ? 62.451 -13.302 -23.536 1.00 194.78 ? 425 SER A CB 1 ATOM 3053 O OG . SER A 1 398 ? 62.812 -14.551 -22.966 1.00 201.10 ? 425 SER A OG 1 ATOM 3054 N N . SER A 1 399 ? 65.238 -11.135 -24.298 1.00 188.07 ? 426 SER A N 1 ATOM 3055 C CA . SER A 1 399 ? 66.544 -11.086 -24.937 1.00 189.38 ? 426 SER A CA 1 ATOM 3056 C C . SER A 1 399 ? 67.252 -9.786 -24.598 1.00 190.99 ? 426 SER A C 1 ATOM 3057 O O . SER A 1 399 ? 66.610 -8.792 -24.254 1.00 192.73 ? 426 SER A O 1 ATOM 3058 C CB . SER A 1 399 ? 66.442 -11.220 -26.459 1.00 179.84 ? 426 SER A CB 1 ATOM 3059 O OG . SER A 1 399 ? 65.926 -10.035 -27.034 1.00 177.27 ? 426 SER A OG 1 ATOM 3060 N N . ALA A 1 400 ? 68.576 -9.787 -24.711 1.00 186.10 ? 427 ALA A N 1 ATOM 3061 C CA . ALA A 1 400 ? 69.348 -8.615 -24.349 1.00 181.60 ? 427 ALA A CA 1 ATOM 3062 C C . ALA A 1 400 ? 69.154 -7.644 -25.494 1.00 190.71 ? 427 ALA A C 1 ATOM 3063 O O . ALA A 1 400 ? 68.844 -8.066 -26.611 1.00 192.13 ? 427 ALA A O 1 ATOM 3064 C CB . ALA A 1 400 ? 70.812 -8.954 -24.140 1.00 178.14 ? 427 ALA A CB 1 ATOM 3065 N N . PRO A 1 401 ? 69.325 -6.341 -25.230 1.00 195.24 ? 428 PRO A N 1 ATOM 3066 C CA . PRO A 1 401 ? 69.398 -5.384 -26.336 1.00 196.75 ? 428 PRO A CA 1 ATOM 3067 C C . PRO A 1 401 ? 70.451 -5.747 -27.374 1.00 202.47 ? 428 PRO A C 1 ATOM 3068 O O . PRO A 1 401 ? 71.509 -6.291 -27.054 1.00 205.77 ? 428 PRO A O 1 ATOM 3069 C CB . PRO A 1 401 ? 69.797 -4.066 -25.656 1.00 191.63 ? 428 PRO A CB 1 ATOM 3070 C CG . PRO A 1 401 ? 70.011 -4.388 -24.210 1.00 191.63 ? 428 PRO A CG 1 ATOM 3071 C CD . PRO A 1 401 ? 69.333 -5.674 -23.920 1.00 191.82 ? 428 PRO A CD 1 ATOM 3072 N N . ARG A 1 402 ? 70.141 -5.417 -28.621 1.00 204.87 ? 429 ARG A N 1 ATOM 3073 C CA . ARG A 1 402 ? 70.950 -5.795 -29.765 1.00 209.79 ? 429 ARG A CA 1 ATOM 3074 C C . ARG A 1 402 ? 71.721 -4.554 -30.172 1.00 207.12 ? 429 ARG A C 1 ATOM 3075 O O . ARG A 1 402 ? 71.321 -3.430 -29.854 1.00 197.08 ? 429 ARG A O 1 ATOM 3076 C CB . ARG A 1 402 ? 70.115 -6.353 -30.926 1.00 207.77 ? 429 ARG A CB 1 ATOM 3077 C CG . ARG A 1 402 ? 70.948 -7.014 -32.050 1.00 199.30 ? 429 ARG A CG 1 ATOM 3078 C CD . ARG A 1 402 ? 72.186 -7.736 -31.497 1.00 196.87 ? 429 ARG A CD 1 ATOM 3079 N NE . ARG A 1 402 ? 73.060 -8.308 -32.527 1.00 200.42 ? 429 ARG A NE 1 ATOM 3080 C CZ . ARG A 1 402 ? 73.973 -7.630 -33.220 1.00 204.07 ? 429 ARG A CZ 1 ATOM 3081 N NH1 . ARG A 1 402 ? 74.138 -6.333 -33.030 1.00 203.35 ? 429 ARG A NH1 1 ATOM 3082 N NH2 . ARG A 1 402 ? 74.716 -8.250 -34.126 1.00 202.96 ? 429 ARG A NH2 1 ATOM 3083 N N . ASP A 1 403 ? 72.814 -4.781 -30.888 1.00 215.31 ? 430 ASP A N 1 ATOM 3084 C CA . ASP A 1 403 ? 73.615 -3.733 -31.481 1.00 219.07 ? 430 ASP A CA 1 ATOM 3085 C C . ASP A 1 403 ? 73.993 -2.708 -30.433 1.00 217.05 ? 430 ASP A C 1 ATOM 3086 O O . ASP A 1 403 ? 73.780 -1.509 -30.621 1.00 213.60 ? 430 ASP A O 1 ATOM 3087 C CB . ASP A 1 403 ? 72.799 -3.086 -32.624 1.00 210.98 ? 430 ASP A CB 1 ATOM 3088 C CG . ASP A 1 403 ? 73.585 -2.070 -33.442 1.00 207.32 ? 430 ASP A CG 1 ATOM 3089 O OD1 . ASP A 1 403 ? 74.284 -2.485 -34.388 1.00 188.92 ? 430 ASP A OD1 1 ATOM 3090 O OD2 . ASP A 1 403 ? 73.464 -0.854 -33.171 1.00 211.66 ? 430 ASP A OD2 1 ATOM 3091 N N . VAL A 1 404 ? 74.487 -3.171 -29.281 1.00 215.58 ? 431 VAL A N 1 ATOM 3092 C CA . VAL A 1 404 ? 74.846 -2.159 -28.326 1.00 212.15 ? 431 VAL A CA 1 ATOM 3093 C C . VAL A 1 404 ? 76.118 -1.644 -28.970 1.00 211.82 ? 431 VAL A C 1 ATOM 3094 O O . VAL A 1 404 ? 77.058 -2.415 -29.178 1.00 217.16 ? 431 VAL A O 1 ATOM 3095 C CB . VAL A 1 404 ? 75.089 -2.748 -26.923 1.00 203.88 ? 431 VAL A CB 1 ATOM 3096 C CG1 . VAL A 1 404 ? 75.510 -1.670 -25.935 1.00 195.27 ? 431 VAL A CG1 1 ATOM 3097 C CG2 . VAL A 1 404 ? 73.842 -3.471 -26.445 1.00 198.97 ? 431 VAL A CG2 1 ATOM 3098 N N . GLN A 1 405 ? 76.189 -0.349 -29.228 1.00 202.77 ? 432 GLN A N 1 ATOM 3099 C CA . GLN A 1 405 ? 77.365 0.233 -29.871 1.00 203.42 ? 432 GLN A CA 1 ATOM 3100 C C . GLN A 1 405 ? 77.734 1.557 -29.236 1.00 210.38 ? 432 GLN A C 1 ATOM 3101 O O . GLN A 1 405 ? 76.872 2.261 -28.720 1.00 208.28 ? 432 GLN A O 1 ATOM 3102 C CB . GLN A 1 405 ? 77.206 0.298 -31.398 1.00 201.17 ? 432 GLN A CB 1 ATOM 3103 C CG . GLN A 1 405 ? 77.049 -1.118 -31.985 1.00 214.08 ? 432 GLN A CG 1 ATOM 3104 C CD . GLN A 1 405 ? 76.704 -1.178 -33.450 1.00 216.11 ? 432 GLN A CD 1 ATOM 3105 O OE1 . GLN A 1 405 ? 76.407 -0.165 -34.077 1.00 215.87 ? 432 GLN A OE1 1 ATOM 3106 N NE2 . GLN A 1 405 ? 76.739 -2.386 -34.011 1.00 213.03 ? 432 GLN A NE2 1 ATOM 3107 N N . ALA A 1 406 ? 79.011 1.898 -29.245 1.00 219.34 ? 433 ALA A N 1 ATOM 3108 C CA . ALA A 1 406 ? 79.399 3.213 -28.763 1.00 219.58 ? 433 ALA A CA 1 ATOM 3109 C C . ALA A 1 406 ? 80.531 3.857 -29.547 1.00 220.66 ? 433 ALA A C 1 ATOM 3110 O O . ALA A 1 406 ? 81.439 3.170 -30.019 1.00 220.16 ? 433 ALA A O 1 ATOM 3111 C CB . ALA A 1 406 ? 79.779 3.124 -27.294 1.00 211.90 ? 433 ALA A CB 1 ATOM 3112 N N . ARG A 1 407 ? 80.466 5.175 -29.715 1.00 219.67 ? 434 ARG A N 1 ATOM 3113 C CA . ARG A 1 407 ? 81.601 5.867 -30.299 1.00 214.57 ? 434 ARG A CA 1 ATOM 3114 C C . ARG A 1 407 ? 81.760 7.185 -29.558 1.00 214.69 ? 434 ARG A C 1 ATOM 3115 O O . ARG A 1 407 ? 80.807 7.753 -29.021 1.00 211.66 ? 434 ARG A O 1 ATOM 3116 C CB . ARG A 1 407 ? 81.415 6.163 -31.798 1.00 211.40 ? 434 ARG A CB 1 ATOM 3117 C CG . ARG A 1 407 ? 80.959 7.611 -32.035 1.00 204.06 ? 434 ARG A CG 1 ATOM 3118 C CD . ARG A 1 407 ? 80.687 8.022 -33.468 1.00 198.31 ? 434 ARG A CD 1 ATOM 3119 N NE . ARG A 1 407 ? 80.003 9.314 -33.431 1.00 189.82 ? 434 ARG A NE 1 ATOM 3120 C CZ . ARG A 1 407 ? 79.542 9.974 -34.488 1.00 185.86 ? 434 ARG A CZ 1 ATOM 3121 N NH1 . ARG A 1 407 ? 79.717 9.492 -35.709 1.00 175.11 ? 434 ARG A NH1 1 ATOM 3122 N NH2 . ARG A 1 407 ? 78.937 11.143 -34.319 1.00 186.53 ? 434 ARG A NH2 1 ATOM 3123 N N . MET A 1 408 ? 83.005 7.627 -29.509 1.00 220.75 ? 435 MET A N 1 ATOM 3124 C CA . MET A 1 408 ? 83.426 8.877 -28.898 1.00 217.26 ? 435 MET A CA 1 ATOM 3125 C C . MET A 1 408 ? 82.963 10.206 -29.524 1.00 207.01 ? 435 MET A C 1 ATOM 3126 O O . MET A 1 408 ? 82.986 10.352 -30.749 1.00 202.47 ? 435 MET A O 1 ATOM 3127 C CB . MET A 1 408 ? 84.941 8.847 -28.799 1.00 226.43 ? 435 MET A CB 1 ATOM 3128 C CG . MET A 1 408 ? 85.453 8.135 -27.565 1.00 226.98 ? 435 MET A CG 1 ATOM 3129 S SD . MET A 1 408 ? 85.260 9.227 -26.158 1.00 217.70 ? 435 MET A SD 1 ATOM 3130 C CE . MET A 1 408 ? 85.481 10.781 -27.003 1.00 209.21 ? 435 MET A CE 1 ATOM 3131 N N . LEU A 1 409 ? 82.545 11.171 -28.703 1.00 202.25 ? 436 LEU A N 1 ATOM 3132 C CA . LEU A 1 409 ? 82.374 12.541 -29.202 1.00 202.87 ? 436 LEU A CA 1 ATOM 3133 C C . LEU A 1 409 ? 83.490 13.520 -28.755 1.00 202.68 ? 436 LEU A C 1 ATOM 3134 O O . LEU A 1 409 ? 84.500 13.646 -29.449 1.00 200.86 ? 436 LEU A O 1 ATOM 3135 C CB . LEU A 1 409 ? 80.992 13.087 -28.851 1.00 199.87 ? 436 LEU A CB 1 ATOM 3136 C CG . LEU A 1 409 ? 80.311 13.491 -30.170 1.00 188.63 ? 436 LEU A CG 1 ATOM 3137 C CD1 . LEU A 1 409 ? 80.389 12.354 -31.190 1.00 182.61 ? 436 LEU A CD1 1 ATOM 3138 C CD2 . LEU A 1 409 ? 78.871 13.934 -29.976 1.00 172.37 ? 436 LEU A CD2 1 ATOM 3139 N N . SER A 1 410 ? 83.333 14.193 -27.604 1.00 198.65 ? 437 SER A N 1 ATOM 3140 C CA . SER A 1 410 ? 84.418 15.057 -27.096 1.00 196.83 ? 437 SER A CA 1 ATOM 3141 C C . SER A 1 410 ? 85.318 14.432 -26.011 1.00 201.26 ? 437 SER A C 1 ATOM 3142 O O . SER A 1 410 ? 85.123 13.287 -25.641 1.00 199.44 ? 437 SER A O 1 ATOM 3143 C CB . SER A 1 410 ? 83.813 16.360 -26.566 1.00 177.66 ? 437 SER A CB 1 ATOM 3144 O OG . SER A 1 410 ? 83.225 16.171 -25.291 1.00 163.87 ? 437 SER A OG 1 ATOM 3145 N N . SER A 1 411 ? 86.246 15.204 -25.438 1.00 203.68 ? 438 SER A N 1 ATOM 3146 C CA . SER A 1 411 ? 87.097 14.690 -24.346 1.00 195.27 ? 438 SER A CA 1 ATOM 3147 C C . SER A 1 411 ? 86.541 14.362 -22.949 1.00 192.45 ? 438 SER A C 1 ATOM 3148 O O . SER A 1 411 ? 87.214 13.686 -22.169 1.00 192.86 ? 438 SER A O 1 ATOM 3149 C CB . SER A 1 411 ? 88.240 15.691 -24.141 1.00 182.30 ? 438 SER A CB 1 ATOM 3150 O OG . SER A 1 411 ? 88.628 15.751 -22.780 1.00 169.81 ? 438 SER A OG 1 ATOM 3151 N N . THR A 1 412 ? 85.337 14.815 -22.629 1.00 192.85 ? 439 THR A N 1 ATOM 3152 C CA . THR A 1 412 ? 84.776 14.619 -21.290 1.00 188.39 ? 439 THR A CA 1 ATOM 3153 C C . THR A 1 412 ? 83.407 13.988 -21.451 1.00 191.73 ? 439 THR A C 1 ATOM 3154 O O . THR A 1 412 ? 82.698 13.719 -20.481 1.00 185.84 ? 439 THR A O 1 ATOM 3155 C CB . THR A 1 412 ? 84.663 15.930 -20.483 1.00 183.56 ? 439 THR A CB 1 ATOM 3156 O OG1 . THR A 1 412 ? 83.716 16.802 -21.108 1.00 192.43 ? 439 THR A OG1 1 ATOM 3157 C CG2 . THR A 1 412 ? 86.016 16.628 -20.381 1.00 175.13 ? 439 THR A CG2 1 ATOM 3158 N N . THR A 1 413 ? 83.076 13.719 -22.706 1.00 197.80 ? 440 THR A N 1 ATOM 3159 C CA . THR A 1 413 ? 81.769 13.223 -23.095 1.00 196.43 ? 440 THR A CA 1 ATOM 3160 C C . THR A 1 413 ? 81.842 12.182 -24.197 1.00 195.90 ? 440 THR A C 1 ATOM 3161 O O . THR A 1 413 ? 82.664 12.271 -25.109 1.00 193.92 ? 440 THR A O 1 ATOM 3162 C CB . THR A 1 413 ? 80.870 14.396 -23.565 1.00 193.26 ? 440 THR A CB 1 ATOM 3163 O OG1 . THR A 1 413 ? 80.828 15.402 -22.546 1.00 192.89 ? 440 THR A OG1 1 ATOM 3164 C CG2 . THR A 1 413 ? 79.452 13.931 -23.864 1.00 192.83 ? 440 THR A CG2 1 ATOM 3165 N N . ILE A 1 414 ? 80.970 11.189 -24.099 1.00 193.82 ? 441 ILE A N 1 ATOM 3166 C CA . ILE A 1 414 ? 80.902 10.144 -25.094 1.00 193.82 ? 441 ILE A CA 1 ATOM 3167 C C . ILE A 1 414 ? 79.473 10.120 -25.598 1.00 196.63 ? 441 ILE A C 1 ATOM 3168 O O . ILE A 1 414 ? 78.568 10.663 -24.963 1.00 195.02 ? 441 ILE A O 1 ATOM 3169 C CB . ILE A 1 414 ? 81.259 8.761 -24.506 1.00 183.38 ? 441 ILE A CB 1 ATOM 3170 C CG1 . ILE A 1 414 ? 80.273 8.378 -23.401 1.00 174.76 ? 441 ILE A CG1 1 ATOM 3171 C CG2 . ILE A 1 414 ? 82.670 8.755 -23.961 1.00 182.99 ? 441 ILE A CG2 1 ATOM 3172 C CD1 . ILE A 1 414 ? 80.491 6.986 -22.845 1.00 178.17 ? 441 ILE A CD1 1 ATOM 3173 N N . LEU A 1 415 ? 79.276 9.510 -26.757 1.00 199.75 ? 442 LEU A N 1 ATOM 3174 C CA . LEU A 1 415 ? 77.944 9.356 -27.310 1.00 196.75 ? 442 LEU A CA 1 ATOM 3175 C C . LEU A 1 415 ? 77.580 7.886 -27.347 1.00 201.48 ? 442 LEU A C 1 ATOM 3176 O O . LEU A 1 415 ? 78.293 7.088 -27.953 1.00 209.72 ? 442 LEU A O 1 ATOM 3177 C CB . LEU A 1 415 ? 77.895 9.967 -28.722 1.00 193.01 ? 442 LEU A CB 1 ATOM 3178 C CG . LEU A 1 415 ? 76.621 10.094 -29.565 1.00 191.91 ? 442 LEU A CG 1 ATOM 3179 C CD1 . LEU A 1 415 ? 76.898 11.005 -30.749 1.00 183.25 ? 442 LEU A CD1 1 ATOM 3180 C CD2 . LEU A 1 415 ? 76.098 8.754 -30.067 1.00 189.50 ? 442 LEU A CD2 1 ATOM 3181 N N . VAL A 1 416 ? 76.477 7.516 -26.710 1.00 196.67 ? 443 VAL A N 1 ATOM 3182 C CA . VAL A 1 416 ? 76.095 6.124 -26.746 1.00 192.62 ? 443 VAL A CA 1 ATOM 3183 C C . VAL A 1 416 ? 74.794 6.022 -27.518 1.00 190.62 ? 443 VAL A C 1 ATOM 3184 O O . VAL A 1 416 ? 73.861 6.787 -27.281 1.00 193.98 ? 443 VAL A O 1 ATOM 3185 C CB . VAL A 1 416 ? 75.911 5.539 -25.325 1.00 191.74 ? 443 VAL A CB 1 ATOM 3186 C CG1 . VAL A 1 416 ? 75.564 4.063 -25.390 1.00 192.16 ? 443 VAL A CG1 1 ATOM 3187 C CG2 . VAL A 1 416 ? 77.166 5.764 -24.491 1.00 187.32 ? 443 VAL A CG2 1 ATOM 3188 N N . GLN A 1 417 ? 74.735 5.073 -28.441 1.00 189.85 ? 444 GLN A N 1 ATOM 3189 C CA . GLN A 1 417 ? 73.521 4.808 -29.185 1.00 191.60 ? 444 GLN A CA 1 ATOM 3190 C C . GLN A 1 417 ? 73.369 3.317 -29.423 1.00 194.59 ? 444 GLN A C 1 ATOM 3191 O O . GLN A 1 417 ? 74.333 2.568 -29.313 1.00 194.46 ? 444 GLN A O 1 ATOM 3192 C CB . GLN A 1 417 ? 73.546 5.583 -30.511 1.00 194.35 ? 444 GLN A CB 1 ATOM 3193 C CG . GLN A 1 417 ? 74.666 5.170 -31.453 1.00 204.65 ? 444 GLN A CG 1 ATOM 3194 C CD . GLN A 1 417 ? 75.069 6.282 -32.409 1.00 191.37 ? 444 GLN A CD 1 ATOM 3195 O OE1 . GLN A 1 417 ? 76.250 6.611 -32.535 1.00 193.10 ? 444 GLN A OE1 1 ATOM 3196 N NE2 . GLN A 1 417 ? 74.086 6.871 -33.081 1.00 176.00 ? 444 GLN A NE2 1 ATOM 3197 N N . TRP A 1 418 ? 72.163 2.880 -29.751 1.00 194.80 ? 445 TRP A N 1 ATOM 3198 C CA . TRP A 1 418 ? 71.905 1.456 -29.904 1.00 195.56 ? 445 TRP A CA 1 ATOM 3199 C C . TRP A 1 418 ? 70.641 1.250 -30.712 1.00 194.38 ? 445 TRP A C 1 ATOM 3200 O O . TRP A 1 418 ? 69.932 2.210 -31.031 1.00 191.24 ? 445 TRP A O 1 ATOM 3201 C CB . TRP A 1 418 ? 71.797 0.739 -28.549 1.00 193.41 ? 445 TRP A CB 1 ATOM 3202 C CG . TRP A 1 418 ? 70.799 1.321 -27.609 1.00 189.56 ? 445 TRP A CG 1 ATOM 3203 C CD1 . TRP A 1 418 ? 69.477 1.004 -27.526 1.00 192.59 ? 445 TRP A CD1 1 ATOM 3204 C CD2 . TRP A 1 418 ? 71.057 2.246 -26.546 1.00 187.86 ? 445 TRP A CD2 1 ATOM 3205 N NE1 . TRP A 1 418 ? 68.882 1.719 -26.520 1.00 191.32 ? 445 TRP A NE1 1 ATOM 3206 C CE2 . TRP A 1 418 ? 69.832 2.482 -25.894 1.00 189.17 ? 445 TRP A CE2 1 ATOM 3207 C CE3 . TRP A 1 418 ? 72.201 2.915 -26.096 1.00 188.20 ? 445 TRP A CE3 1 ATOM 3208 C CZ2 . TRP A 1 418 ? 69.716 3.359 -24.818 1.00 187.15 ? 445 TRP A CZ2 1 ATOM 3209 C CZ3 . TRP A 1 418 ? 72.081 3.785 -25.024 1.00 191.97 ? 445 TRP A CZ3 1 ATOM 3210 C CH2 . TRP A 1 418 ? 70.849 3.996 -24.399 1.00 190.02 ? 445 TRP A CH2 1 ATOM 3211 N N . LYS A 1 419 ? 70.357 -0.000 -31.048 1.00 193.25 ? 446 LYS A N 1 ATOM 3212 C CA . LYS A 1 419 ? 69.095 -0.321 -31.690 1.00 191.26 ? 446 LYS A CA 1 ATOM 3213 C C . LYS A 1 419 ? 68.244 -1.275 -30.865 1.00 205.03 ? 446 LYS A C 1 ATOM 3214 O O . LYS A 1 419 ? 68.746 -2.020 -30.021 1.00 209.94 ? 446 LYS A O 1 ATOM 3215 C CB . LYS A 1 419 ? 69.323 -0.900 -33.084 1.00 176.02 ? 446 LYS A CB 1 ATOM 3216 C CG . LYS A 1 419 ? 69.146 0.138 -34.181 1.00 163.47 ? 446 LYS A CG 1 ATOM 3217 C CD . LYS A 1 419 ? 68.190 -0.354 -35.248 1.00 162.12 ? 446 LYS A CD 1 ATOM 3218 C CE . LYS A 1 419 ? 68.161 0.589 -36.438 1.00 148.97 ? 446 LYS A CE 1 ATOM 3219 N NZ . LYS A 1 419 ? 67.056 0.246 -37.372 1.00 141.98 ? 446 LYS A NZ 1 ATOM 3220 N N . GLU A 1 420 ? 66.943 -1.210 -31.114 1.00 206.29 ? 447 GLU A N 1 ATOM 3221 C CA . GLU A 1 420 ? 65.942 -2.013 -30.424 1.00 204.77 ? 447 GLU A CA 1 ATOM 3222 C C . GLU A 1 420 ? 66.213 -3.520 -30.513 1.00 204.13 ? 447 GLU A C 1 ATOM 3223 O O . GLU A 1 420 ? 66.655 -4.022 -31.540 1.00 206.44 ? 447 GLU A O 1 ATOM 3224 C CB . GLU A 1 420 ? 64.542 -1.676 -30.957 1.00 200.43 ? 447 GLU A CB 1 ATOM 3225 C CG . GLU A 1 420 ? 63.511 -1.529 -29.847 1.00 201.18 ? 447 GLU A CG 1 ATOM 3226 C CD . GLU A 1 420 ? 62.116 -1.244 -30.359 1.00 206.35 ? 447 GLU A CD 1 ATOM 3227 O OE1 . GLU A 1 420 ? 61.577 -2.072 -31.124 1.00 218.52 ? 447 GLU A OE1 1 ATOM 3228 O OE2 . GLU A 1 420 ? 61.556 -0.193 -29.986 1.00 199.80 ? 447 GLU A OE2 1 ATOM 3229 N N . PRO A 1 421 ? 65.936 -4.231 -29.409 1.00 196.07 ? 448 PRO A N 1 ATOM 3230 C CA . PRO A 1 421 ? 65.952 -5.686 -29.209 1.00 194.49 ? 448 PRO A CA 1 ATOM 3231 C C . PRO A 1 421 ? 65.066 -6.443 -30.200 1.00 197.96 ? 448 PRO A C 1 ATOM 3232 O O . PRO A 1 421 ? 64.030 -5.941 -30.632 1.00 198.65 ? 448 PRO A O 1 ATOM 3233 C CB . PRO A 1 421 ? 65.408 -5.859 -27.779 1.00 191.55 ? 448 PRO A CB 1 ATOM 3234 C CG . PRO A 1 421 ? 65.186 -4.470 -27.235 1.00 188.52 ? 448 PRO A CG 1 ATOM 3235 C CD . PRO A 1 421 ? 65.907 -3.522 -28.117 1.00 189.20 ? 448 PRO A CD 1 ATOM 3236 N N . GLU A 1 422 ? 65.500 -7.652 -30.549 1.00 199.89 ? 449 GLU A N 1 ATOM 3237 C CA . GLU A 1 422 ? 64.775 -8.538 -31.459 1.00 196.57 ? 449 GLU A CA 1 ATOM 3238 C C . GLU A 1 422 ? 63.539 -9.049 -30.749 1.00 194.83 ? 449 GLU A C 1 ATOM 3239 O O . GLU A 1 422 ? 62.593 -9.549 -31.358 1.00 188.36 ? 449 GLU A O 1 ATOM 3240 C CB . GLU A 1 422 ? 65.662 -9.723 -31.849 1.00 197.01 ? 449 GLU A CB 1 ATOM 3241 C CG . GLU A 1 422 ? 66.388 -10.323 -30.632 1.00 199.23 ? 449 GLU A CG 1 ATOM 3242 C CD . GLU A 1 422 ? 66.512 -11.839 -30.672 1.00 198.98 ? 449 GLU A CD 1 ATOM 3243 O OE1 . GLU A 1 422 ? 66.917 -12.381 -31.720 1.00 201.04 ? 449 GLU A OE1 1 ATOM 3244 O OE2 . GLU A 1 422 ? 66.207 -12.490 -29.648 1.00 191.39 ? 449 GLU A OE2 1 ATOM 3245 N N . GLU A 1 423 ? 63.592 -8.923 -29.434 1.00 195.22 ? 450 GLU A N 1 ATOM 3246 C CA . GLU A 1 423 ? 62.554 -9.346 -28.520 1.00 192.26 ? 450 GLU A CA 1 ATOM 3247 C C . GLU A 1 423 ? 62.177 -8.107 -27.698 1.00 195.16 ? 450 GLU A C 1 ATOM 3248 O O . GLU A 1 423 ? 62.502 -8.046 -26.510 1.00 193.52 ? 450 GLU A O 1 ATOM 3249 C CB . GLU A 1 423 ? 63.014 -10.509 -27.638 1.00 187.34 ? 450 GLU A CB 1 ATOM 3250 C CG . GLU A 1 423 ? 63.338 -11.800 -28.388 1.00 183.02 ? 450 GLU A CG 1 ATOM 3251 C CD . GLU A 1 423 ? 62.365 -12.929 -28.084 1.00 179.22 ? 450 GLU A CD 1 ATOM 3252 O OE1 . GLU A 1 423 ? 61.143 -12.675 -28.045 1.00 179.07 ? 450 GLU A OE1 1 ATOM 3253 O OE2 . GLU A 1 423 ? 62.827 -14.072 -27.871 1.00 171.85 ? 450 GLU A OE2 1 ATOM 3254 N N . PRO A 1 424 ? 61.531 -7.095 -28.328 1.00 192.86 ? 451 PRO A N 1 ATOM 3255 C CA . PRO A 1 424 ? 61.252 -5.885 -27.539 1.00 191.17 ? 451 PRO A CA 1 ATOM 3256 C C . PRO A 1 424 ? 60.261 -6.265 -26.454 1.00 193.73 ? 451 PRO A C 1 ATOM 3257 O O . PRO A 1 424 ? 60.274 -5.696 -25.361 1.00 194.76 ? 451 PRO A O 1 ATOM 3258 C CB . PRO A 1 424 ? 60.655 -4.919 -28.566 1.00 179.43 ? 451 PRO A CB 1 ATOM 3259 C CG . PRO A 1 424 ? 60.068 -5.808 -29.617 1.00 170.68 ? 451 PRO A CG 1 ATOM 3260 C CD . PRO A 1 424 ? 60.967 -7.016 -29.688 1.00 184.05 ? 451 PRO A CD 1 ATOM 3261 N N . ASN A 1 425 ? 59.392 -7.208 -26.789 1.00 192.56 ? 452 ASN A N 1 ATOM 3262 C CA . ASN A 1 425 ? 58.409 -7.737 -25.861 1.00 190.73 ? 452 ASN A CA 1 ATOM 3263 C C . ASN A 1 425 ? 57.334 -6.935 -25.113 1.00 189.23 ? 452 ASN A C 1 ATOM 3264 O O . ASN A 1 425 ? 56.853 -7.381 -24.070 1.00 182.76 ? 452 ASN A O 1 ATOM 3265 C CB . ASN A 1 425 ? 59.279 -8.480 -24.854 1.00 192.19 ? 452 ASN A CB 1 ATOM 3266 C CG . ASN A 1 425 ? 60.092 -9.575 -25.529 1.00 197.56 ? 452 ASN A CG 1 ATOM 3267 O OD1 . ASN A 1 425 ? 59.600 -10.250 -26.433 1.00 201.66 ? 452 ASN A OD1 1 ATOM 3268 N ND2 . ASN A 1 425 ? 61.346 -9.695 -25.165 1.00 195.21 ? 452 ASN A ND2 1 ATOM 3269 N N . GLY A 1 426 ? 56.951 -5.773 -25.617 1.00 192.52 ? 453 GLY A N 1 ATOM 3270 C CA . GLY A 1 426 ? 55.997 -4.950 -24.898 1.00 186.80 ? 453 GLY A CA 1 ATOM 3271 C C . GLY A 1 426 ? 56.168 -3.534 -25.371 1.00 182.86 ? 453 GLY A C 1 ATOM 3272 O O . GLY A 1 426 ? 56.969 -3.286 -26.273 1.00 187.87 ? 453 GLY A O 1 ATOM 3273 N N . GLN A 1 427 ? 55.422 -2.596 -24.804 1.00 176.85 ? 454 GLN A N 1 ATOM 3274 C CA . GLN A 1 427 ? 55.726 -1.229 -25.156 1.00 183.14 ? 454 GLN A CA 1 ATOM 3275 C C . GLN A 1 427 ? 57.021 -1.032 -24.391 1.00 184.97 ? 454 GLN A C 1 ATOM 3276 O O . GLN A 1 427 ? 57.083 -1.273 -23.184 1.00 178.28 ? 454 GLN A O 1 ATOM 3277 C CB . GLN A 1 427 ? 54.656 -0.211 -24.755 1.00 178.53 ? 454 GLN A CB 1 ATOM 3278 C CG . GLN A 1 427 ? 55.056 1.197 -25.202 1.00 174.56 ? 454 GLN A CG 1 ATOM 3279 C CD . GLN A 1 427 ? 53.925 2.204 -25.162 1.00 151.74 ? 454 GLN A CD 1 ATOM 3280 O OE1 . GLN A 1 427 ? 52.758 1.856 -25.338 1.00 160.80 ? 454 GLN A OE1 1 ATOM 3281 N NE2 . GLN A 1 427 ? 54.272 3.472 -24.963 1.00 123.25 ? 454 GLN A NE2 1 ATOM 3282 N N . ILE A 1 428 ? 58.057 -0.605 -25.099 1.00 188.07 ? 455 ILE A N 1 ATOM 3283 C CA . ILE A 1 428 ? 59.333 -0.312 -24.471 1.00 182.52 ? 455 ILE A CA 1 ATOM 3284 C C . ILE A 1 428 ? 59.123 0.933 -23.634 1.00 184.71 ? 455 ILE A C 1 ATOM 3285 O O . ILE A 1 428 ? 58.780 1.997 -24.148 1.00 189.04 ? 455 ILE A O 1 ATOM 3286 C CB . ILE A 1 428 ? 60.456 -0.115 -25.502 1.00 186.33 ? 455 ILE A CB 1 ATOM 3287 C CG1 . ILE A 1 428 ? 60.655 -1.398 -26.313 1.00 186.82 ? 455 ILE A CG1 1 ATOM 3288 C CG2 . ILE A 1 428 ? 61.749 0.291 -24.814 1.00 189.17 ? 455 ILE A CG2 1 ATOM 3289 C CD1 . ILE A 1 428 ? 60.917 -2.621 -25.464 1.00 184.35 ? 455 ILE A CD1 1 ATOM 3290 N N . GLN A 1 429 ? 59.326 0.784 -22.330 1.00 180.64 ? 456 GLN A N 1 ATOM 3291 C CA . GLN A 1 429 ? 59.117 1.879 -21.406 1.00 183.89 ? 456 GLN A CA 1 ATOM 3292 C C . GLN A 1 429 ? 60.392 2.690 -21.280 1.00 184.85 ? 456 GLN A C 1 ATOM 3293 O O . GLN A 1 429 ? 60.361 3.859 -20.897 1.00 188.32 ? 456 GLN A O 1 ATOM 3294 C CB . GLN A 1 429 ? 58.717 1.334 -20.029 1.00 177.50 ? 456 GLN A CB 1 ATOM 3295 C CG . GLN A 1 429 ? 57.381 0.606 -19.983 1.00 178.66 ? 456 GLN A CG 1 ATOM 3296 C CD . GLN A 1 429 ? 56.216 1.420 -20.502 1.00 181.47 ? 456 GLN A CD 1 ATOM 3297 O OE1 . GLN A 1 429 ? 56.185 2.643 -20.373 1.00 188.20 ? 456 GLN A OE1 1 ATOM 3298 N NE2 . GLN A 1 429 ? 55.237 0.737 -21.088 1.00 170.23 ? 456 GLN A NE2 1 ATOM 3299 N N . GLY A 1 430 ? 61.518 2.063 -21.594 1.00 184.34 ? 457 GLY A N 1 ATOM 3300 C CA . GLY A 1 430 ? 62.780 2.772 -21.613 1.00 193.59 ? 457 GLY A CA 1 ATOM 3301 C C . GLY A 1 430 ? 64.000 1.887 -21.800 1.00 204.72 ? 457 GLY A C 1 ATOM 3302 O O . GLY A 1 430 ? 63.883 0.701 -22.098 1.00 203.40 ? 457 GLY A O 1 ATOM 3303 N N . TYR A 1 431 ? 65.180 2.478 -21.616 1.00 211.42 ? 458 TYR A N 1 ATOM 3304 C CA . TYR A 1 431 ? 66.428 1.730 -21.713 1.00 204.15 ? 458 TYR A CA 1 ATOM 3305 C C . TYR A 1 431 ? 67.257 2.093 -20.508 1.00 196.89 ? 458 TYR A C 1 ATOM 3306 O O . TYR A 1 431 ? 67.080 3.175 -19.927 1.00 191.30 ? 458 TYR A O 1 ATOM 3307 C CB . TYR A 1 431 ? 67.187 2.046 -22.991 1.00 200.45 ? 458 TYR A CB 1 ATOM 3308 C CG . TYR A 1 431 ? 66.488 1.618 -24.254 1.00 205.08 ? 458 TYR A CG 1 ATOM 3309 C CD1 . TYR A 1 431 ? 65.522 2.424 -24.838 1.00 205.13 ? 458 TYR A CD1 1 ATOM 3310 C CD2 . TYR A 1 431 ? 66.769 0.394 -24.845 1.00 202.21 ? 458 TYR A CD2 1 ATOM 3311 C CE1 . TYR A 1 431 ? 64.875 2.039 -25.987 1.00 204.93 ? 458 TYR A CE1 1 ATOM 3312 C CE2 . TYR A 1 431 ? 66.131 0.000 -25.997 1.00 201.82 ? 458 TYR A CE2 1 ATOM 3313 C CZ . TYR A 1 431 ? 65.182 0.825 -26.562 1.00 205.07 ? 458 TYR A CZ 1 ATOM 3314 O OH . TYR A 1 431 ? 64.538 0.447 -27.713 1.00 202.87 ? 458 TYR A OH 1 ATOM 3315 N N . ARG A 1 432 ? 68.161 1.209 -20.111 1.00 196.94 ? 459 ARG A N 1 ATOM 3316 C CA . ARG A 1 432 ? 69.071 1.534 -19.007 1.00 197.80 ? 459 ARG A CA 1 ATOM 3317 C C . ARG A 1 432 ? 70.603 1.438 -19.171 1.00 196.73 ? 459 ARG A C 1 ATOM 3318 O O . ARG A 1 432 ? 71.151 0.374 -19.543 1.00 196.73 ? 459 ARG A O 1 ATOM 3319 C CB . ARG A 1 432 ? 68.639 0.673 -17.837 1.00 203.08 ? 459 ARG A CB 1 ATOM 3320 C CG . ARG A 1 432 ? 69.279 1.054 -16.546 1.00 199.40 ? 459 ARG A CG 1 ATOM 3321 C CD . ARG A 1 432 ? 68.607 2.189 -15.820 1.00 191.74 ? 459 ARG A CD 1 ATOM 3322 N NE . ARG A 1 432 ? 69.044 2.085 -14.438 1.00 186.17 ? 459 ARG A NE 1 ATOM 3323 C CZ . ARG A 1 432 ? 70.210 2.538 -13.997 1.00 184.36 ? 459 ARG A CZ 1 ATOM 3324 N NH1 . ARG A 1 432 ? 71.056 3.135 -14.827 1.00 186.82 ? 459 ARG A NH1 1 ATOM 3325 N NH2 . ARG A 1 432 ? 70.529 2.387 -12.725 1.00 185.38 ? 459 ARG A NH2 1 ATOM 3326 N N . VAL A 1 433 ? 71.268 2.567 -18.873 1.00 195.59 ? 460 VAL A N 1 ATOM 3327 C CA . VAL A 1 433 ? 72.733 2.736 -18.965 1.00 195.10 ? 460 VAL A CA 1 ATOM 3328 C C . VAL A 1 433 ? 73.340 2.646 -17.556 1.00 197.16 ? 460 VAL A C 1 ATOM 3329 O O . VAL A 1 433 ? 72.988 3.450 -16.683 1.00 194.95 ? 460 VAL A O 1 ATOM 3330 C CB . VAL A 1 433 ? 73.149 4.075 -19.597 1.00 189.54 ? 460 VAL A CB 1 ATOM 3331 C CG1 . VAL A 1 433 ? 74.688 4.178 -19.672 1.00 181.96 ? 460 VAL A CG1 1 ATOM 3332 C CG2 . VAL A 1 433 ? 72.534 4.214 -20.979 1.00 198.04 ? 460 VAL A CG2 1 ATOM 3333 N N . TYR A 1 434 ? 74.241 1.687 -17.320 1.00 202.67 ? 461 TYR A N 1 ATOM 3334 C CA . TYR A 1 434 ? 74.868 1.530 -16.004 1.00 203.89 ? 461 TYR A CA 1 ATOM 3335 C C . TYR A 1 434 ? 76.287 2.080 -16.090 1.00 203.22 ? 461 TYR A C 1 ATOM 3336 O O . TYR A 1 434 ? 77.261 1.320 -16.175 1.00 198.78 ? 461 TYR A O 1 ATOM 3337 C CB . TYR A 1 434 ? 74.910 0.048 -15.594 1.00 198.02 ? 461 TYR A CB 1 ATOM 3338 C CG . TYR A 1 434 ? 73.551 -0.584 -15.387 1.00 201.88 ? 461 TYR A CG 1 ATOM 3339 C CD1 . TYR A 1 434 ? 72.682 -0.774 -16.452 1.00 198.20 ? 461 TYR A CD1 1 ATOM 3340 C CD2 . TYR A 1 434 ? 73.105 -0.921 -14.114 1.00 204.46 ? 461 TYR A CD2 1 ATOM 3341 C CE1 . TYR A 1 434 ? 71.432 -1.335 -16.273 1.00 195.46 ? 461 TYR A CE1 1 ATOM 3342 C CE2 . TYR A 1 434 ? 71.859 -1.471 -13.924 1.00 203.67 ? 461 TYR A CE2 1 ATOM 3343 C CZ . TYR A 1 434 ? 71.021 -1.670 -15.002 1.00 198.69 ? 461 TYR A CZ 1 ATOM 3344 O OH . TYR A 1 434 ? 69.780 -2.229 -14.800 1.00 199.02 ? 461 TYR A OH 1 ATOM 3345 N N . TYR A 1 435 ? 76.410 3.403 -16.080 1.00 208.97 ? 462 TYR A N 1 ATOM 3346 C CA . TYR A 1 435 ? 77.706 4.077 -16.203 1.00 215.62 ? 462 TYR A CA 1 ATOM 3347 C C . TYR A 1 435 ? 78.264 4.343 -14.820 1.00 217.77 ? 462 TYR A C 1 ATOM 3348 O O . TYR A 1 435 ? 77.507 4.504 -13.871 1.00 217.94 ? 462 TYR A O 1 ATOM 3349 C CB . TYR A 1 435 ? 77.657 5.415 -16.960 1.00 220.36 ? 462 TYR A CB 1 ATOM 3350 C CG . TYR A 1 435 ? 76.814 6.523 -16.360 1.00 209.76 ? 462 TYR A CG 1 ATOM 3351 C CD1 . TYR A 1 435 ? 75.440 6.556 -16.492 1.00 195.64 ? 462 TYR A CD1 1 ATOM 3352 C CD2 . TYR A 1 435 ? 77.429 7.571 -15.675 1.00 202.34 ? 462 TYR A CD2 1 ATOM 3353 C CE1 . TYR A 1 435 ? 74.706 7.585 -15.933 1.00 186.24 ? 462 TYR A CE1 1 ATOM 3354 C CE2 . TYR A 1 435 ? 76.695 8.602 -15.120 1.00 193.66 ? 462 TYR A CE2 1 ATOM 3355 C CZ . TYR A 1 435 ? 75.329 8.601 -15.255 1.00 187.62 ? 462 TYR A CZ 1 ATOM 3356 O OH . TYR A 1 435 ? 74.580 9.619 -14.713 1.00 189.38 ? 462 TYR A OH 1 ATOM 3357 N N . THR A 1 436 ? 79.587 4.372 -14.705 1.00 217.61 ? 463 THR A N 1 ATOM 3358 C CA . THR A 1 436 ? 80.228 4.555 -13.413 1.00 222.35 ? 463 THR A CA 1 ATOM 3359 C C . THR A 1 436 ? 81.665 4.971 -13.637 1.00 222.04 ? 463 THR A C 1 ATOM 3360 O O . THR A 1 436 ? 82.207 4.775 -14.717 1.00 220.52 ? 463 THR A O 1 ATOM 3361 C CB . THR A 1 436 ? 80.217 3.261 -12.581 1.00 224.62 ? 463 THR A CB 1 ATOM 3362 O OG1 . THR A 1 436 ? 80.703 3.531 -11.260 1.00 227.57 ? 463 THR A OG1 1 ATOM 3363 C CG2 . THR A 1 436 ? 81.087 2.193 -13.230 1.00 219.92 ? 463 THR A CG2 1 ATOM 3364 N N . MET A 1 437 ? 82.275 5.541 -12.602 1.00 220.45 ? 464 MET A N 1 ATOM 3365 C CA . MET A 1 437 ? 83.702 5.845 -12.594 1.00 217.23 ? 464 MET A CA 1 ATOM 3366 C C . MET A 1 437 ? 84.565 4.735 -12.000 1.00 222.27 ? 464 MET A C 1 ATOM 3367 O O . MET A 1 437 ? 85.780 4.715 -12.193 1.00 219.35 ? 464 MET A O 1 ATOM 3368 C CB . MET A 1 437 ? 83.932 7.164 -11.845 1.00 211.09 ? 464 MET A CB 1 ATOM 3369 C CG . MET A 1 437 ? 83.488 8.389 -12.643 1.00 201.19 ? 464 MET A CG 1 ATOM 3370 S SD . MET A 1 437 ? 83.659 9.977 -11.806 1.00 194.75 ? 464 MET A SD 1 ATOM 3371 C CE . MET A 1 437 ? 82.438 9.815 -10.506 1.00 204.93 ? 464 MET A CE 1 ATOM 3372 N N . ASP A 1 438 ? 83.931 3.818 -11.278 1.00 229.73 ? 465 ASP A N 1 ATOM 3373 C CA . ASP A 1 438 ? 84.649 2.758 -10.579 1.00 225.95 ? 465 ASP A CA 1 ATOM 3374 C C . ASP A 1 438 ? 84.144 1.373 -10.974 1.00 225.48 ? 465 ASP A C 1 ATOM 3375 O O . ASP A 1 438 ? 83.171 0.875 -10.409 1.00 232.53 ? 465 ASP A O 1 ATOM 3376 C CB . ASP A 1 438 ? 84.530 2.953 -9.066 1.00 225.98 ? 465 ASP A CB 1 ATOM 3377 C CG . ASP A 1 438 ? 83.226 3.619 -8.665 1.00 228.16 ? 465 ASP A CG 1 ATOM 3378 O OD1 . ASP A 1 438 ? 82.235 3.494 -9.415 1.00 231.81 ? 465 ASP A OD1 1 ATOM 3379 O OD2 . ASP A 1 438 ? 83.195 4.271 -7.601 1.00 226.59 ? 465 ASP A OD2 1 ATOM 3380 N N . PRO A 1 439 ? 84.816 0.741 -11.949 1.00 215.85 ? 466 PRO A N 1 ATOM 3381 C CA . PRO A 1 439 ? 84.411 -0.567 -12.473 1.00 215.13 ? 466 PRO A CA 1 ATOM 3382 C C . PRO A 1 439 ? 84.753 -1.740 -11.552 1.00 222.02 ? 466 PRO A C 1 ATOM 3383 O O . PRO A 1 439 ? 85.209 -2.768 -12.053 1.00 222.77 ? 466 PRO A O 1 ATOM 3384 C CB . PRO A 1 439 ? 85.198 -0.669 -13.783 1.00 201.50 ? 466 PRO A CB 1 ATOM 3385 C CG . PRO A 1 439 ? 86.414 0.139 -13.545 1.00 199.95 ? 466 PRO A CG 1 ATOM 3386 C CD . PRO A 1 439 ? 85.996 1.275 -12.651 1.00 205.97 ? 466 PRO A CD 1 ATOM 3387 N N . THR A 1 440 ? 84.551 -1.595 -10.241 1.00 229.44 ? 467 THR A N 1 ATOM 3388 C CA . THR A 1 440 ? 84.742 -2.717 -9.318 1.00 237.48 ? 467 THR A CA 1 ATOM 3389 C C . THR A 1 440 ? 83.658 -2.808 -8.235 1.00 242.99 ? 467 THR A C 1 ATOM 3390 O O . THR A 1 440 ? 83.536 -3.823 -7.548 1.00 243.54 ? 467 THR A O 1 ATOM 3391 C CB . THR A 1 440 ? 86.108 -2.619 -8.591 1.00 236.60 ? 467 THR A CB 1 ATOM 3392 O OG1 . THR A 1 440 ? 86.109 -1.474 -7.729 1.00 235.89 ? 467 THR A OG1 1 ATOM 3393 C CG2 . THR A 1 440 ? 87.262 -2.499 -9.579 1.00 228.63 ? 467 THR A CG2 1 ATOM 3394 N N . GLN A 1 441 ? 82.874 -1.745 -8.101 1.00 242.78 ? 468 GLN A N 1 ATOM 3395 C CA . GLN A 1 441 ? 81.733 -1.674 -7.181 1.00 240.30 ? 468 GLN A CA 1 ATOM 3396 C C . GLN A 1 441 ? 80.550 -2.608 -7.473 1.00 235.12 ? 468 GLN A C 1 ATOM 3397 O O . GLN A 1 441 ? 80.334 -3.034 -8.609 1.00 234.83 ? 468 GLN A O 1 ATOM 3398 C CB . GLN A 1 441 ? 81.248 -0.230 -7.050 1.00 237.92 ? 468 GLN A CB 1 ATOM 3399 C CG . GLN A 1 441 ? 82.393 0.748 -6.839 1.00 238.29 ? 468 GLN A CG 1 ATOM 3400 C CD . GLN A 1 441 ? 82.292 1.464 -5.503 1.00 229.93 ? 468 GLN A CD 1 ATOM 3401 O OE1 . GLN A 1 441 ? 81.379 1.204 -4.717 1.00 232.53 ? 468 GLN A OE1 1 ATOM 3402 N NE2 . GLN A 1 441 ? 83.244 2.349 -5.227 1.00 217.77 ? 468 GLN A NE2 1 ATOM 3403 N N . HIS A 1 442 ? 79.810 -2.929 -6.413 1.00 236.11 ? 469 HIS A N 1 ATOM 3404 C CA . HIS A 1 442 ? 78.490 -3.548 -6.523 1.00 237.63 ? 469 HIS A CA 1 ATOM 3405 C C . HIS A 1 442 ? 77.603 -2.596 -7.328 1.00 239.74 ? 469 HIS A C 1 ATOM 3406 O O . HIS A 1 442 ? 77.723 -1.379 -7.208 1.00 240.04 ? 469 HIS A O 1 ATOM 3407 C CB . HIS A 1 442 ? 77.901 -3.816 -5.135 1.00 235.79 ? 469 HIS A CB 1 ATOM 3408 C CG . HIS A 1 442 ? 76.896 -4.926 -5.101 1.00 219.23 ? 469 HIS A CG 1 ATOM 3409 N ND1 . HIS A 1 442 ? 75.641 -4.813 -5.658 1.00 215.71 ? 469 HIS A ND1 1 ATOM 3410 C CD2 . HIS A 1 442 ? 76.957 -6.166 -4.559 1.00 202.94 ? 469 HIS A CD2 1 ATOM 3411 C CE1 . HIS A 1 442 ? 74.975 -5.939 -5.470 1.00 206.06 ? 469 HIS A CE1 1 ATOM 3412 N NE2 . HIS A 1 442 ? 75.751 -6.776 -4.805 1.00 195.20 ? 469 HIS A NE2 1 ATOM 3413 N N . VAL A 1 443 ? 76.699 -3.158 -8.128 1.00 239.73 ? 470 VAL A N 1 ATOM 3414 C CA . VAL A 1 443 ? 75.884 -2.367 -9.056 1.00 239.00 ? 470 VAL A CA 1 ATOM 3415 C C . VAL A 1 443 ? 74.968 -1.260 -8.511 1.00 243.62 ? 470 VAL A C 1 ATOM 3416 O O . VAL A 1 443 ? 74.728 -0.283 -9.221 1.00 241.73 ? 470 VAL A O 1 ATOM 3417 C CB . VAL A 1 443 ? 74.981 -3.318 -9.884 1.00 226.34 ? 470 VAL A CB 1 ATOM 3418 C CG1 . VAL A 1 443 ? 75.827 -4.199 -10.788 1.00 215.16 ? 470 VAL A CG1 1 ATOM 3419 C CG2 . VAL A 1 443 ? 74.120 -4.177 -8.965 1.00 222.07 ? 470 VAL A CG2 1 ATOM 3420 N N . ASN A 1 444 ? 74.434 -1.387 -7.300 1.00 245.48 ? 471 ASN A N 1 ATOM 3421 C CA . ASN A 1 444 ? 73.582 -0.315 -6.774 1.00 244.20 ? 471 ASN A CA 1 ATOM 3422 C C . ASN A 1 444 ? 74.372 0.967 -6.460 1.00 243.01 ? 471 ASN A C 1 ATOM 3423 O O . ASN A 1 444 ? 73.801 2.047 -6.301 1.00 242.04 ? 471 ASN A O 1 ATOM 3424 C CB . ASN A 1 444 ? 72.832 -0.786 -5.523 1.00 238.38 ? 471 ASN A CB 1 ATOM 3425 C CG . ASN A 1 444 ? 73.749 -1.408 -4.484 1.00 229.73 ? 471 ASN A CG 1 ATOM 3426 O OD1 . ASN A 1 444 ? 74.302 -2.488 -4.692 1.00 227.10 ? 471 ASN A OD1 1 ATOM 3427 N ND2 . ASN A 1 444 ? 73.910 -0.728 -3.354 1.00 228.06 ? 471 ASN A ND2 1 ATOM 3428 N N . ASN A 1 445 ? 75.691 0.812 -6.385 1.00 241.26 ? 472 ASN A N 1 ATOM 3429 C CA . ASN A 1 445 ? 76.689 1.881 -6.237 1.00 237.41 ? 472 ASN A CA 1 ATOM 3430 C C . ASN A 1 445 ? 77.471 2.374 -7.460 1.00 237.92 ? 472 ASN A C 1 ATOM 3431 O O . ASN A 1 445 ? 78.353 3.221 -7.311 1.00 235.48 ? 472 ASN A O 1 ATOM 3432 C CB . ASN A 1 445 ? 77.698 1.477 -5.162 1.00 231.31 ? 472 ASN A CB 1 ATOM 3433 C CG . ASN A 1 445 ? 77.093 1.471 -3.775 1.00 229.92 ? 472 ASN A CG 1 ATOM 3434 O OD1 . ASN A 1 445 ? 76.955 2.521 -3.144 1.00 228.41 ? 472 ASN A OD1 1 ATOM 3435 N ND2 . ASN A 1 445 ? 76.725 0.293 -3.292 1.00 232.01 ? 472 ASN A ND2 1 ATOM 3436 N N . TRP A 1 446 ? 77.182 1.874 -8.656 1.00 237.35 ? 473 TRP A N 1 ATOM 3437 C CA . TRP A 1 446 ? 77.849 2.439 -9.836 1.00 226.20 ? 473 TRP A CA 1 ATOM 3438 C C . TRP A 1 446 ? 77.529 3.828 -10.400 1.00 222.71 ? 473 TRP A C 1 ATOM 3439 O O . TRP A 1 446 ? 78.466 4.590 -10.530 1.00 222.26 ? 473 TRP A O 1 ATOM 3440 C CB . TRP A 1 446 ? 77.674 1.475 -11.029 1.00 224.67 ? 473 TRP A CB 1 ATOM 3441 C CG . TRP A 1 446 ? 78.388 0.148 -10.956 1.00 228.10 ? 473 TRP A CG 1 ATOM 3442 C CD1 . TRP A 1 446 ? 78.754 -0.537 -9.838 1.00 232.15 ? 473 TRP A CD1 1 ATOM 3443 C CD2 . TRP A 1 446 ? 78.830 -0.644 -12.072 1.00 218.44 ? 473 TRP A CD2 1 ATOM 3444 N NE1 . TRP A 1 446 ? 79.394 -1.703 -10.184 1.00 228.72 ? 473 TRP A NE1 1 ATOM 3445 C CE2 . TRP A 1 446 ? 79.453 -1.794 -11.549 1.00 216.72 ? 473 TRP A CE2 1 ATOM 3446 C CE3 . TRP A 1 446 ? 78.756 -0.492 -13.461 1.00 206.43 ? 473 TRP A CE3 1 ATOM 3447 C CZ2 . TRP A 1 446 ? 80.000 -2.786 -12.363 1.00 195.70 ? 473 TRP A CZ2 1 ATOM 3448 C CZ3 . TRP A 1 446 ? 79.296 -1.478 -14.268 1.00 197.54 ? 473 TRP A CZ3 1 ATOM 3449 C CH2 . TRP A 1 446 ? 79.912 -2.609 -13.717 1.00 190.07 ? 473 TRP A CH2 1 ATOM 3450 N N . MET A 1 447 ? 76.267 4.136 -10.712 1.00 219.62 ? 474 MET A N 1 ATOM 3451 C CA . MET A 1 447 ? 75.690 5.462 -11.088 1.00 211.85 ? 474 MET A CA 1 ATOM 3452 C C . MET A 1 447 ? 74.542 5.072 -11.994 1.00 205.09 ? 474 MET A C 1 ATOM 3453 O O . MET A 1 447 ? 74.570 4.002 -12.603 1.00 201.98 ? 474 MET A O 1 ATOM 3454 C CB . MET A 1 447 ? 76.580 6.548 -11.760 1.00 213.14 ? 474 MET A CB 1 ATOM 3455 C CG . MET A 1 447 ? 77.757 7.148 -10.974 1.00 216.63 ? 474 MET A CG 1 ATOM 3456 S SD . MET A 1 447 ? 78.551 8.554 -11.781 1.00 200.38 ? 474 MET A SD 1 ATOM 3457 C CE . MET A 1 447 ? 77.237 9.770 -11.709 1.00 178.04 ? 474 MET A CE 1 ATOM 3458 N N . LYS A 1 448 ? 73.529 5.921 -12.102 1.00 203.08 ? 475 LYS A N 1 ATOM 3459 C CA . LYS A 1 448 ? 72.306 5.530 -12.776 1.00 200.47 ? 475 LYS A CA 1 ATOM 3460 C C . LYS A 1 448 ? 71.884 6.593 -13.770 1.00 198.58 ? 475 LYS A C 1 ATOM 3461 O O . LYS A 1 448 ? 72.038 7.796 -13.552 1.00 198.15 ? 475 LYS A O 1 ATOM 3462 C CB . LYS A 1 448 ? 71.199 5.338 -11.731 1.00 192.67 ? 475 LYS A CB 1 ATOM 3463 C CG . LYS A 1 448 ? 71.532 4.329 -10.646 1.00 188.84 ? 475 LYS A CG 1 ATOM 3464 C CD . LYS A 1 448 ? 70.589 4.433 -9.462 1.00 174.04 ? 475 LYS A CD 1 ATOM 3465 C CE . LYS A 1 448 ? 70.029 3.069 -9.106 1.00 165.81 ? 475 LYS A CE 1 ATOM 3466 N NZ . LYS A 1 448 ? 69.172 3.097 -7.892 1.00 169.42 ? 475 LYS A NZ 1 ATOM 3467 N N . HIS A 1 449 ? 71.344 6.094 -14.879 1.00 195.77 ? 476 HIS A N 1 ATOM 3468 C CA . HIS A 1 449 ? 70.877 6.911 -15.981 1.00 192.00 ? 476 HIS A CA 1 ATOM 3469 C C . HIS A 1 449 ? 69.508 6.386 -16.407 1.00 187.82 ? 476 HIS A C 1 ATOM 3470 O O . HIS A 1 449 ? 68.969 5.477 -15.773 1.00 183.13 ? 476 HIS A O 1 ATOM 3471 C CB . HIS A 1 449 ? 71.905 6.794 -17.117 1.00 192.50 ? 476 HIS A CB 1 ATOM 3472 C CG . HIS A 1 449 ? 71.543 7.477 -18.397 1.00 197.03 ? 476 HIS A CG 1 ATOM 3473 N ND1 . HIS A 1 449 ? 71.300 8.830 -18.475 1.00 194.50 ? 476 HIS A ND1 1 ATOM 3474 C CD2 . HIS A 1 449 ? 71.383 6.992 -19.650 1.00 200.59 ? 476 HIS A CD2 1 ATOM 3475 C CE1 . HIS A 1 449 ? 71.031 9.151 -19.728 1.00 188.21 ? 476 HIS A CE1 1 ATOM 3476 N NE2 . HIS A 1 449 ? 71.054 8.051 -20.456 1.00 191.65 ? 476 HIS A NE2 1 ATOM 3477 N N . ASN A 1 450 ? 68.951 6.941 -17.475 1.00 190.85 ? 477 ASN A N 1 ATOM 3478 C CA . ASN A 1 450 ? 67.669 6.505 -17.998 1.00 188.32 ? 477 ASN A CA 1 ATOM 3479 C C . ASN A 1 450 ? 67.384 6.986 -19.412 1.00 190.09 ? 477 ASN A C 1 ATOM 3480 O O . ASN A 1 450 ? 67.839 8.053 -19.824 1.00 190.09 ? 477 ASN A O 1 ATOM 3481 C CB . ASN A 1 450 ? 66.534 6.943 -17.072 1.00 187.92 ? 477 ASN A CB 1 ATOM 3482 C CG . ASN A 1 450 ? 65.165 6.494 -17.568 1.00 191.44 ? 477 ASN A CG 1 ATOM 3483 O OD1 . ASN A 1 450 ? 64.697 5.406 -17.231 1.00 195.50 ? 477 ASN A OD1 1 ATOM 3484 N ND2 . ASN A 1 450 ? 64.516 7.338 -18.365 1.00 186.71 ? 477 ASN A ND2 1 ATOM 3485 N N . VAL A 1 451 ? 66.719 6.142 -20.185 1.00 188.61 ? 478 VAL A N 1 ATOM 3486 C CA . VAL A 1 451 ? 66.346 6.487 -21.541 1.00 189.61 ? 478 VAL A CA 1 ATOM 3487 C C . VAL A 1 451 ? 64.892 6.046 -21.556 1.00 190.10 ? 478 VAL A C 1 ATOM 3488 O O . VAL A 1 451 ? 64.516 5.137 -20.820 1.00 190.90 ? 478 VAL A O 1 ATOM 3489 C CB . VAL A 1 451 ? 67.193 5.749 -22.606 1.00 189.66 ? 478 VAL A CB 1 ATOM 3490 C CG1 . VAL A 1 451 ? 66.703 6.067 -24.015 1.00 182.56 ? 478 VAL A CG1 1 ATOM 3491 C CG2 . VAL A 1 451 ? 68.665 6.103 -22.462 1.00 185.25 ? 478 VAL A CG2 1 ATOM 3492 N N . ALA A 1 452 ? 64.066 6.710 -22.355 1.00 185.36 ? 479 ALA A N 1 ATOM 3493 C CA . ALA A 1 452 ? 62.697 6.263 -22.567 1.00 182.42 ? 479 ALA A CA 1 ATOM 3494 C C . ALA A 1 452 ? 62.385 6.128 -24.042 1.00 187.01 ? 479 ALA A C 1 ATOM 3495 O O . ALA A 1 452 ? 61.807 7.034 -24.645 1.00 192.16 ? 479 ALA A O 1 ATOM 3496 C CB . ALA A 1 452 ? 61.717 7.226 -21.906 1.00 175.83 ? 479 ALA A CB 1 ATOM 3497 N N . ASP A 1 453 ? 62.777 4.991 -24.610 1.00 186.77 ? 480 ASP A N 1 ATOM 3498 C CA . ASP A 1 453 ? 62.484 4.672 -26.000 1.00 196.49 ? 480 ASP A CA 1 ATOM 3499 C C . ASP A 1 453 ? 63.029 5.764 -26.917 1.00 198.70 ? 480 ASP A C 1 ATOM 3500 O O . ASP A 1 453 ? 62.289 6.359 -27.701 1.00 204.48 ? 480 ASP A O 1 ATOM 3501 C CB . ASP A 1 453 ? 60.975 4.496 -26.195 1.00 203.30 ? 480 ASP A CB 1 ATOM 3502 C CG . ASP A 1 453 ? 60.627 3.789 -27.489 1.00 201.28 ? 480 ASP A CG 1 ATOM 3503 O OD1 . ASP A 1 453 ? 61.540 3.232 -28.131 1.00 208.04 ? 480 ASP A OD1 1 ATOM 3504 O OD2 . ASP A 1 453 ? 59.434 3.788 -27.863 1.00 188.55 ? 480 ASP A OD2 1 ATOM 3505 N N . SER A 1 454 ? 64.328 6.026 -26.804 1.00 193.09 ? 481 SER A N 1 ATOM 3506 C CA . SER A 1 454 ? 64.980 7.067 -27.593 1.00 192.95 ? 481 SER A CA 1 ATOM 3507 C C . SER A 1 454 ? 66.207 6.528 -28.329 1.00 192.68 ? 481 SER A C 1 ATOM 3508 O O . SER A 1 454 ? 66.890 7.258 -29.045 1.00 190.57 ? 481 SER A O 1 ATOM 3509 C CB . SER A 1 454 ? 65.372 8.236 -26.688 1.00 181.15 ? 481 SER A CB 1 ATOM 3510 O OG . SER A 1 454 ? 66.028 9.259 -27.416 1.00 175.55 ? 481 SER A OG 1 ATOM 3511 N N . GLN A 1 455 ? 66.469 5.240 -28.132 1.00 196.15 ? 482 GLN A N 1 ATOM 3512 C CA . GLN A 1 455 ? 67.619 4.517 -28.687 1.00 194.72 ? 482 GLN A CA 1 ATOM 3513 C C . GLN A 1 455 ? 68.999 5.183 -28.561 1.00 192.56 ? 482 GLN A C 1 ATOM 3514 O O . GLN A 1 455 ? 69.986 4.625 -29.038 1.00 190.11 ? 482 GLN A O 1 ATOM 3515 C CB . GLN A 1 455 ? 67.391 4.213 -30.181 1.00 189.17 ? 482 GLN A CB 1 ATOM 3516 C CG . GLN A 1 455 ? 66.108 3.461 -30.550 1.00 187.90 ? 482 GLN A CG 1 ATOM 3517 C CD . GLN A 1 455 ? 64.842 4.270 -30.336 1.00 199.12 ? 482 GLN A CD 1 ATOM 3518 O OE1 . GLN A 1 455 ? 63.896 3.810 -29.697 1.00 206.65 ? 482 GLN A OE1 1 ATOM 3519 N NE2 . GLN A 1 455 ? 64.815 5.481 -30.884 1.00 195.76 ? 482 GLN A NE2 1 ATOM 3520 N N . ILE A 1 456 ? 69.091 6.350 -27.929 1.00 192.61 ? 483 ILE A N 1 ATOM 3521 C CA . ILE A 1 456 ? 70.378 7.039 -27.855 1.00 192.85 ? 483 ILE A CA 1 ATOM 3522 C C . ILE A 1 456 ? 70.479 7.968 -26.643 1.00 186.39 ? 483 ILE A C 1 ATOM 3523 O O . ILE A 1 456 ? 69.506 8.625 -26.269 1.00 184.17 ? 483 ILE A O 1 ATOM 3524 C CB . ILE A 1 456 ? 70.634 7.855 -29.161 1.00 190.73 ? 483 ILE A CB 1 ATOM 3525 C CG1 . ILE A 1 456 ? 72.035 8.469 -29.171 1.00 179.87 ? 483 ILE A CG1 1 ATOM 3526 C CG2 . ILE A 1 456 ? 69.608 8.966 -29.331 1.00 191.52 ? 483 ILE A CG2 1 ATOM 3527 C CD1 . ILE A 1 456 ? 72.428 9.073 -30.505 1.00 168.76 ? 483 ILE A CD1 1 ATOM 3528 N N . THR A 1 457 ? 71.653 8.002 -26.014 1.00 186.07 ? 484 THR A N 1 ATOM 3529 C CA . THR A 1 457 ? 71.883 8.925 -24.907 1.00 180.08 ? 484 THR A CA 1 ATOM 3530 C C . THR A 1 457 ? 73.355 9.330 -24.732 1.00 184.06 ? 484 THR A C 1 ATOM 3531 O O . THR A 1 457 ? 74.259 8.634 -25.194 1.00 189.81 ? 484 THR A O 1 ATOM 3532 C CB . THR A 1 457 ? 71.376 8.321 -23.597 1.00 173.96 ? 484 THR A CB 1 ATOM 3533 O OG1 . THR A 1 457 ? 71.408 9.318 -22.572 1.00 176.54 ? 484 THR A OG1 1 ATOM 3534 C CG2 . THR A 1 457 ? 72.244 7.135 -23.192 1.00 177.14 ? 484 THR A CG2 1 ATOM 3535 N N . THR A 1 458 ? 73.586 10.451 -24.054 1.00 182.96 ? 485 THR A N 1 ATOM 3536 C CA . THR A 1 458 ? 74.938 10.911 -23.725 1.00 176.95 ? 485 THR A CA 1 ATOM 3537 C C . THR A 1 458 ? 75.235 10.814 -22.220 1.00 180.20 ? 485 THR A C 1 ATOM 3538 O O . THR A 1 458 ? 74.326 10.952 -21.400 1.00 183.10 ? 485 THR A O 1 ATOM 3539 C CB . THR A 1 458 ? 75.180 12.359 -24.217 1.00 174.17 ? 485 THR A CB 1 ATOM 3540 O OG1 . THR A 1 458 ? 74.263 13.254 -23.576 1.00 165.79 ? 485 THR A OG1 1 ATOM 3541 C CG2 . THR A 1 458 ? 74.991 12.444 -25.726 1.00 179.42 ? 485 THR A CG2 1 ATOM 3542 N N . ILE A 1 459 ? 76.493 10.580 -21.851 1.00 186.12 ? 486 ILE A N 1 ATOM 3543 C CA . ILE A 1 459 ? 76.872 10.590 -20.436 1.00 192.36 ? 486 ILE A CA 1 ATOM 3544 C C . ILE A 1 459 ? 78.101 11.488 -20.292 1.00 196.01 ? 486 ILE A C 1 ATOM 3545 O O . ILE A 1 459 ? 79.119 11.317 -20.969 1.00 188.14 ? 486 ILE A O 1 ATOM 3546 C CB . ILE A 1 459 ? 77.130 9.174 -19.836 1.00 189.54 ? 486 ILE A CB 1 ATOM 3547 C CG1 . ILE A 1 459 ? 78.386 8.518 -20.404 1.00 184.59 ? 486 ILE A CG1 1 ATOM 3548 C CG2 . ILE A 1 459 ? 75.903 8.286 -20.016 1.00 194.57 ? 486 ILE A CG2 1 ATOM 3549 C CD1 . ILE A 1 459 ? 78.881 7.345 -19.591 1.00 188.90 ? 486 ILE A CD1 1 ATOM 3550 N N . GLY A 1 460 ? 77.979 12.481 -19.421 1.00 203.50 ? 487 GLY A N 1 ATOM 3551 C CA . GLY A 1 460 ? 79.048 13.434 -19.226 1.00 198.95 ? 487 GLY A CA 1 ATOM 3552 C C . GLY A 1 460 ? 79.711 13.355 -17.873 1.00 204.41 ? 487 GLY A C 1 ATOM 3553 O O . GLY A 1 460 ? 79.536 12.383 -17.134 1.00 204.51 ? 487 GLY A O 1 ATOM 3554 N N . ASN A 1 461 ? 80.502 14.383 -17.574 1.00 201.40 ? 488 ASN A N 1 ATOM 3555 C CA . ASN A 1 461 ? 81.254 14.456 -16.332 1.00 199.45 ? 488 ASN A CA 1 ATOM 3556 C C . ASN A 1 461 ? 82.166 13.274 -16.183 1.00 191.53 ? 488 ASN A C 1 ATOM 3557 O O . ASN A 1 461 ? 82.397 12.828 -15.055 1.00 182.76 ? 488 ASN A O 1 ATOM 3558 C CB . ASN A 1 461 ? 80.348 14.519 -15.104 1.00 197.26 ? 488 ASN A CB 1 ATOM 3559 C CG . ASN A 1 461 ? 79.716 15.868 -14.910 1.00 200.51 ? 488 ASN A CG 1 ATOM 3560 O OD1 . ASN A 1 461 ? 80.003 16.811 -15.642 1.00 204.23 ? 488 ASN A OD1 1 ATOM 3561 N ND2 . ASN A 1 461 ? 78.861 15.979 -13.899 1.00 194.79 ? 488 ASN A ND2 1 ATOM 3562 N N . LEU A 1 462 ? 82.699 12.735 -17.274 1.00 187.77 ? 489 LEU A N 1 ATOM 3563 C CA . LEU A 1 462 ? 83.576 11.642 -16.990 1.00 187.12 ? 489 LEU A CA 1 ATOM 3564 C C . LEU A 1 462 ? 84.886 12.381 -16.832 1.00 190.22 ? 489 LEU A C 1 ATOM 3565 O O . LEU A 1 462 ? 85.063 13.450 -17.420 1.00 185.57 ? 489 LEU A O 1 ATOM 3566 C CB . LEU A 1 462 ? 83.582 10.662 -18.164 1.00 185.87 ? 489 LEU A CB 1 ATOM 3567 C CG . LEU A 1 462 ? 82.153 10.246 -18.534 1.00 184.68 ? 489 LEU A CG 1 ATOM 3568 C CD1 . LEU A 1 462 ? 82.142 9.316 -19.725 1.00 185.88 ? 489 LEU A CD1 1 ATOM 3569 C CD2 . LEU A 1 462 ? 81.432 9.626 -17.346 1.00 181.01 ? 489 LEU A CD2 1 ATOM 3570 N N . VAL A 1 463 ? 85.830 11.814 -16.103 1.00 197.14 ? 490 VAL A N 1 ATOM 3571 C CA . VAL A 1 463 ? 87.145 12.431 -15.956 1.00 194.78 ? 490 VAL A CA 1 ATOM 3572 C C . VAL A 1 463 ? 88.077 11.778 -16.977 1.00 195.05 ? 490 VAL A C 1 ATOM 3573 O O . VAL A 1 463 ? 88.043 10.551 -17.105 1.00 197.86 ? 490 VAL A O 1 ATOM 3574 C CB . VAL A 1 463 ? 87.672 12.374 -14.499 1.00 182.65 ? 490 VAL A CB 1 ATOM 3575 C CG1 . VAL A 1 463 ? 87.443 11.034 -13.883 1.00 182.38 ? 490 VAL A CG1 1 ATOM 3576 C CG2 . VAL A 1 463 ? 89.135 12.798 -14.426 1.00 168.69 ? 490 VAL A CG2 1 ATOM 3577 N N . PRO A 1 464 ? 88.852 12.555 -17.748 1.00 192.15 ? 491 PRO A N 1 ATOM 3578 C CA . PRO A 1 464 ? 89.645 11.906 -18.803 1.00 188.24 ? 491 PRO A CA 1 ATOM 3579 C C . PRO A 1 464 ? 90.635 10.885 -18.216 1.00 190.83 ? 491 PRO A C 1 ATOM 3580 O O . PRO A 1 464 ? 91.036 11.040 -17.062 1.00 192.95 ? 491 PRO A O 1 ATOM 3581 C CB . PRO A 1 464 ? 90.382 13.073 -19.480 1.00 180.92 ? 491 PRO A CB 1 ATOM 3582 C CG . PRO A 1 464 ? 90.136 14.277 -18.618 1.00 187.52 ? 491 PRO A CG 1 ATOM 3583 C CD . PRO A 1 464 ? 88.849 14.018 -17.895 1.00 191.69 ? 491 PRO A CD 1 ATOM 3584 N N . GLN A 1 465 ? 90.976 9.851 -18.986 1.00 192.20 ? 492 GLN A N 1 ATOM 3585 C CA . GLN A 1 465 ? 91.995 8.856 -18.616 1.00 193.74 ? 492 GLN A CA 1 ATOM 3586 C C . GLN A 1 465 ? 91.649 7.977 -17.401 1.00 195.21 ? 492 GLN A C 1 ATOM 3587 O O . GLN A 1 465 ? 92.511 7.661 -16.581 1.00 196.34 ? 492 GLN A O 1 ATOM 3588 C CB . GLN A 1 465 ? 93.326 9.570 -18.342 1.00 196.16 ? 492 GLN A CB 1 ATOM 3589 C CG . GLN A 1 465 ? 94.013 10.135 -19.575 1.00 193.89 ? 492 GLN A CG 1 ATOM 3590 C CD . GLN A 1 465 ? 95.068 11.174 -19.237 1.00 189.59 ? 492 GLN A CD 1 ATOM 3591 O OE1 . GLN A 1 465 ? 95.359 11.426 -18.067 1.00 183.26 ? 492 GLN A OE1 1 ATOM 3592 N NE2 . GLN A 1 465 ? 95.632 11.798 -20.265 1.00 189.10 ? 492 GLN A NE2 1 ATOM 3593 N N . LYS A 1 466 ? 90.379 7.584 -17.309 1.00 201.78 ? 493 LYS A N 1 ATOM 3594 C CA . LYS A 1 466 ? 89.883 6.729 -16.231 1.00 202.27 ? 493 LYS A CA 1 ATOM 3595 C C . LYS A 1 466 ? 89.126 5.581 -16.915 1.00 208.05 ? 493 LYS A C 1 ATOM 3596 O O . LYS A 1 466 ? 88.556 5.790 -17.984 1.00 211.13 ? 493 LYS A O 1 ATOM 3597 C CB . LYS A 1 466 ? 88.986 7.510 -15.264 1.00 196.22 ? 493 LYS A CB 1 ATOM 3598 C CG . LYS A 1 466 ? 88.551 6.720 -14.036 1.00 187.37 ? 493 LYS A CG 1 ATOM 3599 C CD . LYS A 1 466 ? 87.601 7.508 -13.138 1.00 185.75 ? 493 LYS A CD 1 ATOM 3600 C CE . LYS A 1 466 ? 88.343 8.273 -12.046 1.00 176.85 ? 493 LYS A CE 1 ATOM 3601 N NZ . LYS A 1 466 ? 87.443 9.219 -11.316 1.00 165.98 ? 493 LYS A NZ 1 ATOM 3602 N N . THR A 1 467 ? 89.117 4.380 -16.333 1.00 207.14 ? 494 THR A N 1 ATOM 3603 C CA . THR A 1 467 ? 88.257 3.314 -16.863 1.00 204.88 ? 494 THR A CA 1 ATOM 3604 C C . THR A 1 467 ? 86.822 3.307 -16.319 1.00 202.92 ? 494 THR A C 1 ATOM 3605 O O . THR A 1 467 ? 86.605 3.112 -15.124 1.00 201.49 ? 494 THR A O 1 ATOM 3606 C CB . THR A 1 467 ? 88.886 1.931 -16.591 1.00 202.86 ? 494 THR A CB 1 ATOM 3607 O OG1 . THR A 1 467 ? 90.139 1.830 -17.281 1.00 201.65 ? 494 THR A OG1 1 ATOM 3608 C CG2 . THR A 1 467 ? 87.969 0.816 -17.063 1.00 192.46 ? 494 THR A CG2 1 ATOM 3609 N N . TYR A 1 468 ? 85.852 3.537 -17.204 1.00 207.94 ? 495 TYR A N 1 ATOM 3610 C CA . TYR A 1 468 ? 84.428 3.369 -16.902 1.00 218.00 ? 495 TYR A CA 1 ATOM 3611 C C . TYR A 1 468 ? 83.857 2.049 -17.441 1.00 211.70 ? 495 TYR A C 1 ATOM 3612 O O . TYR A 1 468 ? 84.012 1.775 -18.627 1.00 207.47 ? 495 TYR A O 1 ATOM 3613 C CB . TYR A 1 468 ? 83.656 4.565 -17.464 1.00 224.81 ? 495 TYR A CB 1 ATOM 3614 C CG . TYR A 1 468 ? 84.346 5.878 -17.160 1.00 216.63 ? 495 TYR A CG 1 ATOM 3615 C CD1 . TYR A 1 468 ? 84.060 6.582 -16.002 1.00 213.94 ? 495 TYR A CD1 1 ATOM 3616 C CD2 . TYR A 1 468 ? 85.301 6.401 -18.022 1.00 206.09 ? 495 TYR A CD2 1 ATOM 3617 C CE1 . TYR A 1 468 ? 84.693 7.761 -15.712 1.00 203.41 ? 495 TYR A CE1 1 ATOM 3618 C CE2 . TYR A 1 468 ? 85.943 7.583 -17.733 1.00 197.90 ? 495 TYR A CE2 1 ATOM 3619 C CZ . TYR A 1 468 ? 85.629 8.258 -16.578 1.00 196.00 ? 495 TYR A CZ 1 ATOM 3620 O OH . TYR A 1 468 ? 86.254 9.439 -16.280 1.00 194.18 ? 495 TYR A OH 1 ATOM 3621 N N . SER A 1 469 ? 83.182 1.243 -16.620 1.00 207.21 ? 496 SER A N 1 ATOM 3622 C CA . SER A 1 469 ? 82.488 0.060 -17.157 1.00 200.44 ? 496 SER A CA 1 ATOM 3623 C C . SER A 1 469 ? 81.019 0.330 -17.534 1.00 203.15 ? 496 SER A C 1 ATOM 3624 O O . SER A 1 469 ? 80.313 1.026 -16.804 1.00 199.89 ? 496 SER A O 1 ATOM 3625 C CB . SER A 1 469 ? 82.559 -1.094 -16.156 1.00 194.97 ? 496 SER A CB 1 ATOM 3626 O OG . SER A 1 469 ? 82.165 -0.676 -14.862 1.00 197.17 ? 496 SER A OG 1 ATOM 3627 N N . VAL A 1 470 ? 80.555 -0.227 -18.656 1.00 206.92 ? 497 VAL A N 1 ATOM 3628 C CA . VAL A 1 470 ? 79.190 0.045 -19.135 1.00 204.31 ? 497 VAL A CA 1 ATOM 3629 C C . VAL A 1 470 ? 78.435 -1.230 -19.552 1.00 199.57 ? 497 VAL A C 1 ATOM 3630 O O . VAL A 1 470 ? 78.977 -2.063 -20.279 1.00 200.40 ? 497 VAL A O 1 ATOM 3631 C CB . VAL A 1 470 ? 79.202 1.022 -20.333 1.00 197.67 ? 497 VAL A CB 1 ATOM 3632 C CG1 . VAL A 1 470 ? 77.797 1.217 -20.892 1.00 194.52 ? 497 VAL A CG1 1 ATOM 3633 C CG2 . VAL A 1 470 ? 79.811 2.361 -19.931 1.00 194.03 ? 497 VAL A CG2 1 ATOM 3634 N N . LYS A 1 471 ? 77.194 -1.391 -19.086 1.00 193.53 ? 498 LYS A N 1 ATOM 3635 C CA . LYS A 1 471 ? 76.334 -2.510 -19.499 1.00 194.02 ? 498 LYS A CA 1 ATOM 3636 C C . LYS A 1 471 ? 74.912 -2.000 -19.830 1.00 193.49 ? 498 LYS A C 1 ATOM 3637 O O . LYS A 1 471 ? 74.466 -1.042 -19.201 1.00 190.73 ? 498 LYS A O 1 ATOM 3638 C CB . LYS A 1 471 ? 76.335 -3.577 -18.394 1.00 193.63 ? 498 LYS A CB 1 ATOM 3639 C CG . LYS A 1 471 ? 77.768 -4.040 -18.069 1.00 193.86 ? 498 LYS A CG 1 ATOM 3640 C CD . LYS A 1 471 ? 77.937 -4.821 -16.775 1.00 190.69 ? 498 LYS A CD 1 ATOM 3641 C CE . LYS A 1 471 ? 77.439 -6.240 -16.893 1.00 186.25 ? 498 LYS A CE 1 ATOM 3642 N NZ . LYS A 1 471 ? 78.359 -7.173 -16.186 1.00 167.61 ? 498 LYS A NZ 1 ATOM 3643 N N . VAL A 1 472 ? 74.190 -2.607 -20.783 1.00 196.57 ? 499 VAL A N 1 ATOM 3644 C CA . VAL A 1 472 ? 72.848 -2.087 -21.123 1.00 190.37 ? 499 VAL A CA 1 ATOM 3645 C C . VAL A 1 472 ? 71.759 -3.180 -21.193 1.00 193.03 ? 499 VAL A C 1 ATOM 3646 O O . VAL A 1 472 ? 71.979 -4.259 -21.743 1.00 198.33 ? 499 VAL A O 1 ATOM 3647 C CB . VAL A 1 472 ? 72.871 -1.348 -22.492 1.00 182.42 ? 499 VAL A CB 1 ATOM 3648 C CG1 . VAL A 1 472 ? 71.517 -0.720 -22.800 1.00 186.54 ? 499 VAL A CG1 1 ATOM 3649 C CG2 . VAL A 1 472 ? 73.972 -0.294 -22.532 1.00 173.85 ? 499 VAL A CG2 1 ATOM 3650 N N . LEU A 1 473 ? 70.594 -2.880 -20.609 1.00 192.86 ? 500 LEU A N 1 ATOM 3651 C CA . LEU A 1 473 ? 69.340 -3.655 -20.709 1.00 195.63 ? 500 LEU A CA 1 ATOM 3652 C C . LEU A 1 473 ? 68.058 -2.912 -21.159 1.00 193.76 ? 500 LEU A C 1 ATOM 3653 O O . LEU A 1 473 ? 67.985 -1.689 -21.048 1.00 192.63 ? 500 LEU A O 1 ATOM 3654 C CB . LEU A 1 473 ? 69.107 -4.345 -19.362 1.00 202.10 ? 500 LEU A CB 1 ATOM 3655 C CG . LEU A 1 473 ? 68.893 -3.518 -18.089 1.00 202.12 ? 500 LEU A CG 1 ATOM 3656 C CD1 . LEU A 1 473 ? 67.534 -2.830 -17.964 1.00 204.05 ? 500 LEU A CD1 1 ATOM 3657 C CD2 . LEU A 1 473 ? 69.174 -4.422 -16.899 1.00 193.09 ? 500 LEU A CD2 1 ATOM 3658 N N . ALA A 1 474 ? 67.058 -3.643 -21.667 1.00 195.98 ? 501 ALA A N 1 ATOM 3659 C CA . ALA A 1 474 ? 65.732 -3.048 -21.909 1.00 204.01 ? 501 ALA A CA 1 ATOM 3660 C C . ALA A 1 474 ? 64.724 -3.517 -20.834 1.00 204.54 ? 501 ALA A C 1 ATOM 3661 O O . ALA A 1 474 ? 64.864 -4.611 -20.290 1.00 203.79 ? 501 ALA A O 1 ATOM 3662 C CB . ALA A 1 474 ? 65.233 -3.401 -23.301 1.00 206.34 ? 501 ALA A CB 1 ATOM 3663 N N . PHE A 1 475 ? 63.712 -2.694 -20.543 1.00 206.82 ? 502 PHE A N 1 ATOM 3664 C CA . PHE A 1 475 ? 62.587 -3.053 -19.652 1.00 203.10 ? 502 PHE A CA 1 ATOM 3665 C C . PHE A 1 475 ? 61.165 -2.728 -20.166 1.00 203.02 ? 502 PHE A C 1 ATOM 3666 O O . PHE A 1 475 ? 60.979 -1.741 -20.878 1.00 203.35 ? 502 PHE A O 1 ATOM 3667 C CB . PHE A 1 475 ? 62.784 -2.412 -18.273 1.00 204.48 ? 502 PHE A CB 1 ATOM 3668 C CG . PHE A 1 475 ? 62.826 -0.911 -18.287 1.00 208.00 ? 502 PHE A CG 1 ATOM 3669 C CD1 . PHE A 1 475 ? 61.672 -0.168 -18.101 1.00 206.08 ? 502 PHE A CD1 1 ATOM 3670 C CD2 . PHE A 1 475 ? 64.027 -0.242 -18.457 1.00 199.04 ? 502 PHE A CD2 1 ATOM 3671 C CE1 . PHE A 1 475 ? 61.711 1.213 -18.102 1.00 198.72 ? 502 PHE A CE1 1 ATOM 3672 C CE2 . PHE A 1 475 ? 64.073 1.137 -18.458 1.00 198.50 ? 502 PHE A CE2 1 ATOM 3673 C CZ . PHE A 1 475 ? 62.913 1.866 -18.279 1.00 199.02 ? 502 PHE A CZ 1 ATOM 3674 N N . THR A 1 476 ? 60.171 -3.552 -19.818 1.00 196.84 ? 503 THR A N 1 ATOM 3675 C CA . THR A 1 476 ? 58.774 -3.170 -20.075 1.00 195.28 ? 503 THR A CA 1 ATOM 3676 C C . THR A 1 476 ? 58.118 -2.726 -18.756 1.00 191.87 ? 503 THR A C 1 ATOM 3677 O O . THR A 1 476 ? 58.781 -2.718 -17.718 1.00 187.89 ? 503 THR A O 1 ATOM 3678 C CB . THR A 1 476 ? 57.955 -4.319 -20.702 1.00 194.02 ? 503 THR A CB 1 ATOM 3679 O OG1 . THR A 1 476 ? 57.937 -5.443 -19.814 1.00 195.64 ? 503 THR A OG1 1 ATOM 3680 C CG2 . THR A 1 476 ? 58.547 -4.738 -22.043 1.00 192.83 ? 503 THR A CG2 1 ATOM 3681 N N . SER A 1 477 ? 56.836 -2.352 -18.785 1.00 192.39 ? 504 SER A N 1 ATOM 3682 C CA . SER A 1 477 ? 56.106 -2.037 -17.544 1.00 194.22 ? 504 SER A CA 1 ATOM 3683 C C . SER A 1 477 ? 55.979 -3.118 -16.471 1.00 200.72 ? 504 SER A C 1 ATOM 3684 O O . SER A 1 477 ? 55.838 -2.797 -15.290 1.00 204.78 ? 504 SER A O 1 ATOM 3685 C CB . SER A 1 477 ? 54.683 -1.581 -17.897 1.00 182.52 ? 504 SER A CB 1 ATOM 3686 O OG . SER A 1 477 ? 54.680 -0.355 -18.606 1.00 177.10 ? 504 SER A OG 1 ATOM 3687 N N . ILE A 1 478 ? 56.021 -4.385 -16.860 1.00 203.09 ? 505 ILE A N 1 ATOM 3688 C CA . ILE A 1 478 ? 55.942 -5.462 -15.877 1.00 202.88 ? 505 ILE A CA 1 ATOM 3689 C C . ILE A 1 478 ? 57.260 -5.588 -15.115 1.00 192.07 ? 505 ILE A C 1 ATOM 3690 O O . ILE A 1 478 ? 57.280 -5.719 -13.891 1.00 189.36 ? 505 ILE A O 1 ATOM 3691 C CB . ILE A 1 478 ? 55.553 -6.792 -16.493 1.00 202.97 ? 505 ILE A CB 1 ATOM 3692 C CG1 . ILE A 1 478 ? 54.228 -6.661 -17.247 1.00 201.96 ? 505 ILE A CG1 1 ATOM 3693 C CG2 . ILE A 1 478 ? 55.431 -7.835 -15.391 1.00 195.67 ? 505 ILE A CG2 1 ATOM 3694 C CD1 . ILE A 1 478 ? 53.071 -6.214 -16.381 1.00 199.80 ? 505 ILE A CD1 1 ATOM 3695 N N . GLY A 1 479 ? 58.361 -5.538 -15.863 1.00 184.76 ? 506 GLY A N 1 ATOM 3696 C CA . GLY A 1 479 ? 59.686 -5.714 -15.299 1.00 186.44 ? 506 GLY A CA 1 ATOM 3697 C C . GLY A 1 479 ? 60.816 -5.814 -16.312 1.00 194.36 ? 506 GLY A C 1 ATOM 3698 O O . GLY A 1 479 ? 60.603 -5.726 -17.522 1.00 189.28 ? 506 GLY A O 1 ATOM 3699 N N . ASP A 1 480 ? 62.023 -6.014 -15.791 1.00 204.61 ? 507 ASP A N 1 ATOM 3700 C CA . ASP A 1 480 ? 63.261 -6.116 -16.573 1.00 205.45 ? 507 ASP A CA 1 ATOM 3701 C C . ASP A 1 480 ? 63.644 -7.362 -17.390 1.00 204.05 ? 507 ASP A C 1 ATOM 3702 O O . ASP A 1 480 ? 63.488 -8.499 -16.943 1.00 202.44 ? 507 ASP A O 1 ATOM 3703 C CB . ASP A 1 480 ? 64.410 -5.856 -15.599 1.00 201.10 ? 507 ASP A CB 1 ATOM 3704 C CG . ASP A 1 480 ? 65.608 -5.246 -16.266 1.00 199.44 ? 507 ASP A CG 1 ATOM 3705 O OD1 . ASP A 1 480 ? 65.654 -5.220 -17.514 1.00 202.65 ? 507 ASP A OD1 1 ATOM 3706 O OD2 . ASP A 1 480 ? 66.502 -4.780 -15.531 1.00 195.22 ? 507 ASP A OD2 1 ATOM 3707 N N . GLY A 1 481 ? 64.146 -7.105 -18.602 1.00 204.72 ? 508 GLY A N 1 ATOM 3708 C CA . GLY A 1 481 ? 64.776 -8.107 -19.452 1.00 202.56 ? 508 GLY A CA 1 ATOM 3709 C C . GLY A 1 481 ? 66.269 -8.268 -19.163 1.00 197.77 ? 508 GLY A C 1 ATOM 3710 O O . GLY A 1 481 ? 66.787 -7.660 -18.229 1.00 197.08 ? 508 GLY A O 1 ATOM 3711 N N . PRO A 1 482 ? 66.970 -9.099 -19.964 1.00 192.61 ? 509 PRO A N 1 ATOM 3712 C CA . PRO A 1 482 ? 68.420 -9.359 -19.825 1.00 195.82 ? 509 PRO A CA 1 ATOM 3713 C C . PRO A 1 482 ? 69.410 -8.224 -20.197 1.00 194.65 ? 509 PRO A C 1 ATOM 3714 O O . PRO A 1 482 ? 69.132 -7.362 -21.034 1.00 191.11 ? 509 PRO A O 1 ATOM 3715 C CB . PRO A 1 482 ? 68.651 -10.570 -20.742 1.00 195.90 ? 509 PRO A CB 1 ATOM 3716 C CG . PRO A 1 482 ? 67.413 -10.763 -21.511 1.00 189.84 ? 509 PRO A CG 1 ATOM 3717 C CD . PRO A 1 482 ? 66.293 -10.114 -20.790 1.00 185.85 ? 509 PRO A CD 1 ATOM 3718 N N . LEU A 1 483 ? 70.564 -8.268 -19.528 1.00 200.26 ? 510 LEU A N 1 ATOM 3719 C CA . LEU A 1 483 ? 71.748 -7.411 -19.731 1.00 201.68 ? 510 LEU A CA 1 ATOM 3720 C C . LEU A 1 483 ? 72.735 -7.786 -20.868 1.00 200.53 ? 510 LEU A C 1 ATOM 3721 O O . LEU A 1 483 ? 73.024 -8.963 -21.078 1.00 200.23 ? 510 LEU A O 1 ATOM 3722 C CB . LEU A 1 483 ? 72.527 -7.332 -18.415 1.00 197.73 ? 510 LEU A CB 1 ATOM 3723 C CG . LEU A 1 483 ? 73.385 -6.095 -18.184 1.00 190.89 ? 510 LEU A CG 1 ATOM 3724 C CD1 . LEU A 1 483 ? 72.565 -4.839 -18.382 1.00 192.21 ? 510 LEU A CD1 1 ATOM 3725 C CD2 . LEU A 1 483 ? 73.958 -6.123 -16.784 1.00 188.49 ? 510 LEU A CD2 1 ATOM 3726 N N . SER A 1 484 ? 73.248 -6.782 -21.583 1.00 197.73 ? 511 SER A N 1 ATOM 3727 C CA . SER A 1 484 ? 74.349 -6.975 -22.536 1.00 192.44 ? 511 SER A CA 1 ATOM 3728 C C . SER A 1 484 ? 75.631 -6.279 -22.042 1.00 199.70 ? 511 SER A C 1 ATOM 3729 O O . SER A 1 484 ? 75.548 -5.276 -21.335 1.00 203.15 ? 511 SER A O 1 ATOM 3730 C CB . SER A 1 484 ? 73.965 -6.450 -23.921 1.00 190.86 ? 511 SER A CB 1 ATOM 3731 O OG . SER A 1 484 ? 73.535 -5.101 -23.842 1.00 197.87 ? 511 SER A OG 1 ATOM 3732 N N . SER A 1 485 ? 76.808 -6.791 -22.415 1.00 203.65 ? 512 SER A N 1 ATOM 3733 C CA . SER A 1 485 ? 78.072 -6.115 -22.076 1.00 204.39 ? 512 SER A CA 1 ATOM 3734 C C . SER A 1 485 ? 79.211 -6.299 -23.090 1.00 203.09 ? 512 SER A C 1 ATOM 3735 O O . SER A 1 485 ? 79.229 -7.270 -23.851 1.00 204.33 ? 512 SER A O 1 ATOM 3736 C CB . SER A 1 485 ? 78.557 -6.583 -20.701 1.00 198.34 ? 512 SER A CB 1 ATOM 3737 O OG . SER A 1 485 ? 79.804 -5.990 -20.373 1.00 190.77 ? 512 SER A OG 1 ATOM 3738 N N . ASP A 1 486 ? 80.160 -5.356 -23.054 1.00 200.41 ? 513 ASP A N 1 ATOM 3739 C CA . ASP A 1 486 ? 81.346 -5.312 -23.922 1.00 197.48 ? 513 ASP A CA 1 ATOM 3740 C C . ASP A 1 486 ? 82.086 -3.981 -23.792 1.00 203.83 ? 513 ASP A C 1 ATOM 3741 O O . ASP A 1 486 ? 82.987 -3.691 -24.580 1.00 208.52 ? 513 ASP A O 1 ATOM 3742 C CB . ASP A 1 486 ? 80.969 -5.502 -25.397 1.00 196.97 ? 513 ASP A CB 1 ATOM 3743 C CG . ASP A 1 486 ? 80.152 -4.338 -25.946 1.00 197.91 ? 513 ASP A CG 1 ATOM 3744 O OD1 . ASP A 1 486 ? 78.907 -4.389 -25.858 1.00 200.16 ? 513 ASP A OD1 1 ATOM 3745 O OD2 . ASP A 1 486 ? 80.755 -3.372 -26.462 1.00 190.31 ? 513 ASP A OD2 1 ATOM 3746 N N . ILE A 1 487 ? 81.724 -3.181 -22.793 1.00 206.96 ? 514 ILE A N 1 ATOM 3747 C CA . ILE A 1 487 ? 82.399 -1.903 -22.569 1.00 205.55 ? 514 ILE A CA 1 ATOM 3748 C C . ILE A 1 487 ? 83.106 -1.647 -21.223 1.00 200.12 ? 514 ILE A C 1 ATOM 3749 O O . ILE A 1 487 ? 82.507 -1.782 -20.154 1.00 195.34 ? 514 ILE A O 1 ATOM 3750 C CB . ILE A 1 487 ? 81.366 -0.773 -22.781 1.00 201.99 ? 514 ILE A CB 1 ATOM 3751 C CG1 . ILE A 1 487 ? 80.746 -0.875 -24.180 1.00 194.66 ? 514 ILE A CG1 1 ATOM 3752 C CG2 . ILE A 1 487 ? 81.997 0.566 -22.583 1.00 201.51 ? 514 ILE A CG2 1 ATOM 3753 C CD1 . ILE A 1 487 ? 79.582 0.062 -24.413 1.00 185.13 ? 514 ILE A CD1 1 ATOM 3754 N N . GLN A 1 488 ? 84.386 -1.270 -21.302 1.00 196.65 ? 515 GLN A N 1 ATOM 3755 C CA . GLN A 1 488 ? 85.114 -0.643 -20.191 1.00 197.88 ? 515 GLN A CA 1 ATOM 3756 C C . GLN A 1 488 ? 85.993 0.510 -20.736 1.00 199.75 ? 515 GLN A C 1 ATOM 3757 O O . GLN A 1 488 ? 87.024 0.864 -20.165 1.00 203.04 ? 515 GLN A O 1 ATOM 3758 C CB . GLN A 1 488 ? 85.948 -1.674 -19.415 1.00 200.79 ? 515 GLN A CB 1 ATOM 3759 C CG . GLN A 1 488 ? 85.108 -2.755 -18.718 1.00 200.13 ? 515 GLN A CG 1 ATOM 3760 C CD . GLN A 1 488 ? 85.441 -2.931 -17.244 1.00 199.28 ? 515 GLN A CD 1 ATOM 3761 O OE1 . GLN A 1 488 ? 86.399 -2.349 -16.737 1.00 192.43 ? 515 GLN A OE1 1 ATOM 3762 N NE2 . GLN A 1 488 ? 84.643 -3.738 -16.550 1.00 201.11 ? 515 GLN A NE2 1 ATOM 3763 N N . VAL A 1 489 ? 85.530 1.062 -21.859 1.00 194.63 ? 516 VAL A N 1 ATOM 3764 C CA . VAL A 1 489 ? 86.029 2.251 -22.588 1.00 192.49 ? 516 VAL A CA 1 ATOM 3765 C C . VAL A 1 489 ? 86.726 3.384 -21.790 1.00 199.86 ? 516 VAL A C 1 ATOM 3766 O O . VAL A 1 489 ? 86.337 3.708 -20.666 1.00 198.06 ? 516 VAL A O 1 ATOM 3767 C CB . VAL A 1 489 ? 84.873 2.906 -23.408 1.00 184.84 ? 516 VAL A CB 1 ATOM 3768 C CG1 . VAL A 1 489 ? 83.790 3.403 -22.483 1.00 189.80 ? 516 VAL A CG1 1 ATOM 3769 C CG2 . VAL A 1 489 ? 85.369 4.088 -24.227 1.00 185.18 ? 516 VAL A CG2 1 ATOM 3770 N N . ILE A 1 490 ? 87.768 3.955 -22.400 1.00 203.60 ? 517 ILE A N 1 ATOM 3771 C CA . ILE A 1 490 ? 88.681 4.957 -21.835 1.00 196.73 ? 517 ILE A CA 1 ATOM 3772 C C . ILE A 1 490 ? 88.353 6.240 -22.633 1.00 201.87 ? 517 ILE A C 1 ATOM 3773 O O . ILE A 1 490 ? 88.273 6.229 -23.861 1.00 201.89 ? 517 ILE A O 1 ATOM 3774 C CB . ILE A 1 490 ? 90.160 4.548 -21.931 1.00 178.17 ? 517 ILE A CB 1 ATOM 3775 C CG1 . ILE A 1 490 ? 90.384 3.247 -21.155 1.00 163.09 ? 517 ILE A CG1 1 ATOM 3776 C CG2 . ILE A 1 490 ? 91.052 5.640 -21.357 1.00 177.34 ? 517 ILE A CG2 1 ATOM 3777 C CD1 . ILE A 1 490 ? 91.409 2.322 -21.768 1.00 127.29 ? 517 ILE A CD1 1 ATOM 3778 N N . THR A 1 491 ? 88.182 7.338 -21.896 1.00 202.28 ? 518 THR A N 1 ATOM 3779 C CA . THR A 1 491 ? 87.743 8.669 -22.374 1.00 209.08 ? 518 THR A CA 1 ATOM 3780 C C . THR A 1 491 ? 88.605 9.758 -23.041 1.00 208.21 ? 518 THR A C 1 ATOM 3781 O O . THR A 1 491 ? 88.889 10.788 -22.424 1.00 206.85 ? 518 THR A O 1 ATOM 3782 C CB . THR A 1 491 ? 87.089 9.423 -21.189 1.00 204.12 ? 518 THR A CB 1 ATOM 3783 O OG1 . THR A 1 491 ? 87.932 9.324 -20.033 1.00 194.54 ? 518 THR A OG1 1 ATOM 3784 C CG2 . THR A 1 491 ? 85.726 8.837 -20.871 1.00 204.17 ? 518 THR A CG2 1 ATOM 3785 N N . GLN A 1 492 ? 89.019 9.544 -24.290 1.00 204.28 ? 519 GLN A N 1 ATOM 3786 C CA . GLN A 1 492 ? 89.923 10.487 -24.951 1.00 202.30 ? 519 GLN A CA 1 ATOM 3787 C C . GLN A 1 492 ? 89.287 10.966 -26.273 1.00 210.84 ? 519 GLN A C 1 ATOM 3788 O O . GLN A 1 492 ? 88.203 11.527 -26.216 1.00 214.99 ? 519 GLN A O 1 ATOM 3789 C CB . GLN A 1 492 ? 91.301 9.871 -25.190 1.00 190.83 ? 519 GLN A CB 1 ATOM 3790 C CG . GLN A 1 492 ? 92.215 9.965 -23.975 1.00 177.27 ? 519 GLN A CG 1 ATOM 3791 C CD . GLN A 1 492 ? 92.251 11.364 -23.383 1.00 174.57 ? 519 GLN A CD 1 ATOM 3792 O OE1 . GLN A 1 492 ? 91.974 11.555 -22.198 1.00 165.84 ? 519 GLN A OE1 1 ATOM 3793 N NE2 . GLN A 1 492 ? 92.594 12.349 -24.207 1.00 179.11 ? 519 GLN A NE2 1 ATOM 3794 N N . THR A 1 493 ? 89.923 10.814 -27.436 1.00 214.34 ? 520 THR A N 1 ATOM 3795 C CA . THR A 1 493 ? 89.266 11.218 -28.701 1.00 219.27 ? 520 THR A CA 1 ATOM 3796 C C . THR A 1 493 ? 88.323 10.210 -29.394 1.00 227.52 ? 520 THR A C 1 ATOM 3797 O O . THR A 1 493 ? 88.155 9.081 -28.937 1.00 230.00 ? 520 THR A O 1 ATOM 3798 C CB . THR A 1 493 ? 90.318 11.646 -29.745 1.00 210.39 ? 520 THR A CB 1 ATOM 3799 O OG1 . THR A 1 493 ? 91.566 11.013 -29.457 1.00 211.72 ? 520 THR A OG1 1 ATOM 3800 C CG2 . THR A 1 493 ? 90.507 13.159 -29.724 1.00 196.48 ? 520 THR A CG2 1 ATOM 3801 N N . GLY A 1 494 ? 87.741 10.646 -30.517 1.00 224.97 ? 521 GLY A N 1 ATOM 3802 C CA . GLY A 1 494 ? 86.742 9.894 -31.279 1.00 228.01 ? 521 GLY A CA 1 ATOM 3803 C C . GLY A 1 494 ? 87.211 8.599 -31.920 1.00 229.42 ? 521 GLY A C 1 ATOM 3804 O O . GLY A 1 494 ? 88.375 8.480 -32.253 1.00 227.63 ? 521 GLY A O 1 ATOM 3805 N N . VAL A 1 495 ? 86.332 7.608 -32.082 1.00 227.34 ? 522 VAL A N 1 ATOM 3806 C CA . VAL A 1 495 ? 86.781 6.356 -32.702 1.00 224.17 ? 522 VAL A CA 1 ATOM 3807 C C . VAL A 1 495 ? 85.872 5.800 -33.818 1.00 230.35 ? 522 VAL A C 1 ATOM 3808 O O . VAL A 1 495 ? 84.656 5.997 -33.795 1.00 223.09 ? 522 VAL A O 1 ATOM 3809 C CB . VAL A 1 495 ? 86.953 5.259 -31.615 1.00 219.44 ? 522 VAL A CB 1 ATOM 3810 C CG1 . VAL A 1 495 ? 87.942 5.716 -30.549 1.00 220.24 ? 522 VAL A CG1 1 ATOM 3811 C CG2 . VAL A 1 495 ? 85.617 4.907 -30.984 1.00 215.64 ? 522 VAL A CG2 1 ATOM 3812 N N . PRO A 1 496 ? 86.482 5.113 -34.809 1.00 239.70 ? 523 PRO A N 1 ATOM 3813 C CA . PRO A 1 496 ? 85.850 4.474 -35.975 1.00 240.20 ? 523 PRO A CA 1 ATOM 3814 C C . PRO A 1 496 ? 85.025 3.229 -35.643 1.00 232.46 ? 523 PRO A C 1 ATOM 3815 O O . PRO A 1 496 ? 85.188 2.649 -34.570 1.00 231.34 ? 523 PRO A O 1 ATOM 3816 C CB . PRO A 1 496 ? 87.043 4.103 -36.862 1.00 242.48 ? 523 PRO A CB 1 ATOM 3817 C CG . PRO A 1 496 ? 88.176 3.972 -35.921 1.00 237.53 ? 523 PRO A CG 1 ATOM 3818 C CD . PRO A 1 496 ? 87.951 5.050 -34.907 1.00 235.16 ? 523 PRO A CD 1 ATOM 3819 N N . GLY A 1 497 ? 84.149 2.831 -36.562 1.00 225.08 ? 524 GLY A N 1 ATOM 3820 C CA . GLY A 1 497 ? 83.310 1.660 -36.373 1.00 223.08 ? 524 GLY A CA 1 ATOM 3821 C C . GLY A 1 497 ? 83.825 0.417 -37.085 1.00 221.42 ? 524 GLY A C 1 ATOM 3822 O O . GLY A 1 497 ? 84.155 0.478 -38.269 1.00 220.36 ? 524 GLY A O 1 ATOM 3823 N N . GLN A 1 498 ? 83.924 -0.691 -36.345 1.00 216.56 ? 525 GLN A N 1 ATOM 3824 C CA . GLN A 1 498 ? 84.394 -1.994 -36.847 1.00 217.00 ? 525 GLN A CA 1 ATOM 3825 C C . GLN A 1 498 ? 83.926 -2.308 -38.271 1.00 221.96 ? 525 GLN A C 1 ATOM 3826 O O . GLN A 1 498 ? 82.817 -1.935 -38.660 1.00 219.95 ? 525 GLN A O 1 ATOM 3827 C CB . GLN A 1 498 ? 83.945 -3.120 -35.911 1.00 209.53 ? 525 GLN A CB 1 ATOM 3828 C CG . GLN A 1 498 ? 82.452 -3.400 -35.943 1.00 203.22 ? 525 GLN A CG 1 ATOM 3829 C CD . GLN A 1 498 ? 81.979 -4.184 -34.738 1.00 198.72 ? 525 GLN A CD 1 ATOM 3830 O OE1 . GLN A 1 498 ? 81.809 -3.632 -33.652 1.00 190.34 ? 525 GLN A OE1 1 ATOM 3831 N NE2 . GLN A 1 498 ? 81.763 -5.481 -34.925 1.00 203.70 ? 525 GLN A NE2 1 ATOM 3832 N N . PRO A 1 499 ? 84.769 -2.988 -39.063 1.00 221.24 ? 526 PRO A N 1 ATOM 3833 C CA . PRO A 1 499 ? 84.288 -3.265 -40.420 1.00 210.85 ? 526 PRO A CA 1 ATOM 3834 C C . PRO A 1 499 ? 83.146 -4.283 -40.488 1.00 206.36 ? 526 PRO A C 1 ATOM 3835 O O . PRO A 1 499 ? 82.831 -4.951 -39.503 1.00 198.04 ? 526 PRO A O 1 ATOM 3836 C CB . PRO A 1 499 ? 85.536 -3.826 -41.113 1.00 208.61 ? 526 PRO A CB 1 ATOM 3837 C CG . PRO A 1 499 ? 86.365 -4.389 -40.012 1.00 209.61 ? 526 PRO A CG 1 ATOM 3838 C CD . PRO A 1 499 ? 86.142 -3.475 -38.843 1.00 220.98 ? 526 PRO A CD 1 ATOM 3839 N N . LEU A 1 500 ? 82.531 -4.374 -41.663 1.00 214.50 ? 527 LEU A N 1 ATOM 3840 C CA . LEU A 1 500 ? 81.428 -5.295 -41.921 1.00 217.51 ? 527 LEU A CA 1 ATOM 3841 C C . LEU A 1 500 ? 81.891 -6.318 -42.954 1.00 224.15 ? 527 LEU A C 1 ATOM 3842 O O . LEU A 1 500 ? 83.020 -6.219 -43.433 1.00 228.79 ? 527 LEU A O 1 ATOM 3843 C CB . LEU A 1 500 ? 80.181 -4.540 -42.384 1.00 212.66 ? 527 LEU A CB 1 ATOM 3844 C CG . LEU A 1 500 ? 79.665 -3.526 -41.356 1.00 189.77 ? 527 LEU A CG 1 ATOM 3845 C CD1 . LEU A 1 500 ? 78.937 -2.372 -42.028 1.00 175.22 ? 527 LEU A CD1 1 ATOM 3846 C CD2 . LEU A 1 500 ? 78.777 -4.194 -40.314 1.00 167.58 ? 527 LEU A CD2 1 ATOM 3847 N N . ASN A 1 501 ? 81.018 -7.261 -43.318 1.00 224.04 ? 528 ASN A N 1 ATOM 3848 C CA . ASN A 1 501 ? 81.338 -8.304 -44.304 1.00 223.07 ? 528 ASN A CA 1 ATOM 3849 C C . ASN A 1 501 ? 82.752 -8.838 -44.112 1.00 229.43 ? 528 ASN A C 1 ATOM 3850 O O . ASN A 1 501 ? 83.553 -8.884 -45.046 1.00 230.63 ? 528 ASN A O 1 ATOM 3851 C CB . ASN A 1 501 ? 81.179 -7.761 -45.725 1.00 217.03 ? 528 ASN A CB 1 ATOM 3852 C CG . ASN A 1 501 ? 79.738 -7.442 -46.072 1.00 220.08 ? 528 ASN A CG 1 ATOM 3853 O OD1 . ASN A 1 501 ? 79.117 -8.126 -46.885 1.00 220.48 ? 528 ASN A OD1 1 ATOM 3854 N ND2 . ASN A 1 501 ? 79.202 -6.391 -45.463 1.00 226.20 ? 528 ASN A ND2 1 ATOM 3855 N N . PHE A 1 502 ? 83.042 -9.239 -42.882 1.00 232.36 ? 529 PHE A N 1 ATOM 3856 C CA . PHE A 1 502 ? 84.347 -9.757 -42.510 1.00 229.63 ? 529 PHE A CA 1 ATOM 3857 C C . PHE A 1 502 ? 84.424 -11.278 -42.686 1.00 224.44 ? 529 PHE A C 1 ATOM 3858 O O . PHE A 1 502 ? 83.663 -12.015 -42.063 1.00 214.60 ? 529 PHE A O 1 ATOM 3859 C CB . PHE A 1 502 ? 84.617 -9.343 -41.059 1.00 228.15 ? 529 PHE A CB 1 ATOM 3860 C CG . PHE A 1 502 ? 85.969 -9.714 -40.546 1.00 228.93 ? 529 PHE A CG 1 ATOM 3861 C CD1 . PHE A 1 502 ? 87.095 -9.505 -41.318 1.00 226.98 ? 529 PHE A CD1 1 ATOM 3862 C CD2 . PHE A 1 502 ? 86.121 -10.218 -39.266 1.00 228.00 ? 529 PHE A CD2 1 ATOM 3863 C CE1 . PHE A 1 502 ? 88.341 -9.820 -40.837 1.00 227.91 ? 529 PHE A CE1 1 ATOM 3864 C CE2 . PHE A 1 502 ? 87.367 -10.537 -38.781 1.00 223.95 ? 529 PHE A CE2 1 ATOM 3865 C CZ . PHE A 1 502 ? 88.478 -10.332 -39.566 1.00 226.17 ? 529 PHE A CZ 1 ATOM 3866 N N . LYS A 1 503 ? 85.312 -11.734 -43.572 1.00 228.74 ? 530 LYS A N 1 ATOM 3867 C CA . LYS A 1 503 ? 85.495 -13.167 -43.839 1.00 230.26 ? 530 LYS A CA 1 ATOM 3868 C C . LYS A 1 503 ? 86.959 -13.516 -44.136 1.00 240.65 ? 530 LYS A C 1 ATOM 3869 O O . LYS A 1 503 ? 87.697 -12.698 -44.686 1.00 240.48 ? 530 LYS A O 1 ATOM 3870 C CB . LYS A 1 503 ? 84.621 -13.608 -45.019 1.00 211.87 ? 530 LYS A CB 1 ATOM 3871 C CG . LYS A 1 503 ? 83.133 -13.705 -44.723 1.00 196.02 ? 530 LYS A CG 1 ATOM 3872 C CD . LYS A 1 503 ? 82.443 -14.651 -45.694 1.00 164.83 ? 530 LYS A CD 1 ATOM 3873 C CE . LYS A 1 503 ? 82.558 -16.094 -45.236 1.00 154.66 ? 530 LYS A CE 1 ATOM 3874 N NZ . LYS A 1 503 ? 81.946 -16.296 -43.894 1.00 165.64 ? 530 LYS A NZ 1 ATOM 3875 N N . ALA A 1 504 ? 87.366 -14.733 -43.776 1.00 247.07 ? 531 ALA A N 1 ATOM 3876 C CA . ALA A 1 504 ? 88.737 -15.208 -44.003 1.00 245.72 ? 531 ALA A CA 1 ATOM 3877 C C . ALA A 1 504 ? 88.835 -16.507 -44.804 1.00 247.39 ? 531 ALA A C 1 ATOM 3878 O O . ALA A 1 504 ? 88.154 -17.482 -44.484 1.00 247.60 ? 531 ALA A O 1 ATOM 3879 C CB . ALA A 1 504 ? 89.444 -15.387 -42.685 1.00 234.30 ? 531 ALA A CB 1 ATOM 3880 N N . GLU A 1 505 ? 89.680 -16.535 -45.833 1.00 246.89 ? 532 GLU A N 1 ATOM 3881 C CA . GLU A 1 505 ? 89.822 -17.755 -46.625 1.00 248.02 ? 532 GLU A CA 1 ATOM 3882 C C . GLU A 1 505 ? 91.292 -18.149 -46.834 1.00 252.41 ? 532 GLU A C 1 ATOM 3883 O O . GLU A 1 505 ? 92.141 -17.297 -47.102 1.00 250.77 ? 532 GLU A O 1 ATOM 3884 C CB . GLU A 1 505 ? 89.126 -17.590 -47.982 1.00 242.48 ? 532 GLU A CB 1 ATOM 3885 C CG . GLU A 1 505 ? 89.804 -16.605 -48.927 1.00 235.12 ? 532 GLU A CG 1 ATOM 3886 C CD . GLU A 1 505 ? 88.839 -15.601 -49.520 1.00 233.59 ? 532 GLU A CD 1 ATOM 3887 O OE1 . GLU A 1 505 ? 87.690 -15.984 -49.824 1.00 234.16 ? 532 GLU A OE1 1 ATOM 3888 O OE2 . GLU A 1 505 ? 89.231 -14.426 -49.682 1.00 233.60 ? 532 GLU A OE2 1 ATOM 3889 N N . PRO A 1 506 ? 91.593 -19.451 -46.685 1.00 254.63 ? 533 PRO A N 1 ATOM 3890 C CA . PRO A 1 506 ? 92.928 -20.045 -46.850 1.00 253.61 ? 533 PRO A CA 1 ATOM 3891 C C . PRO A 1 506 ? 93.416 -20.078 -48.301 1.00 253.94 ? 533 PRO A C 1 ATOM 3892 O O . PRO A 1 506 ? 93.128 -21.048 -49.001 1.00 254.50 ? 533 PRO A O 1 ATOM 3893 C CB . PRO A 1 506 ? 92.748 -21.463 -46.304 1.00 249.58 ? 533 PRO A CB 1 ATOM 3894 C CG . PRO A 1 506 ? 91.301 -21.751 -46.471 1.00 244.56 ? 533 PRO A CG 1 ATOM 3895 C CD . PRO A 1 506 ? 90.606 -20.446 -46.228 1.00 245.98 ? 533 PRO A CD 1 ATOM 3896 N N . GLU A 1 507 ? 94.140 -19.056 -48.746 1.00 254.06 ? 534 GLU A N 1 ATOM 3897 C CA . GLU A 1 507 ? 94.635 -19.024 -50.123 1.00 258.44 ? 534 GLU A CA 1 ATOM 3898 C C . GLU A 1 507 ? 95.700 -20.092 -50.417 1.00 262.40 ? 534 GLU A C 1 ATOM 3899 O O . GLU A 1 507 ? 95.952 -20.409 -51.580 1.00 263.11 ? 534 GLU A O 1 ATOM 3900 C CB . GLU A 1 507 ? 95.177 -17.632 -50.474 1.00 257.65 ? 534 GLU A CB 1 ATOM 3901 C CG . GLU A 1 507 ? 96.397 -17.174 -49.697 1.00 254.54 ? 534 GLU A CG 1 ATOM 3902 C CD . GLU A 1 507 ? 97.249 -16.206 -50.500 1.00 236.27 ? 534 GLU A CD 1 ATOM 3903 O OE1 . GLU A 1 507 ? 96.681 -15.260 -51.088 1.00 222.50 ? 534 GLU A OE1 1 ATOM 3904 O OE2 . GLU A 1 507 ? 98.483 -16.392 -50.558 1.00 232.50 ? 534 GLU A OE2 1 ATOM 3905 N N . SER A 1 508 ? 96.315 -20.647 -49.373 1.00 264.37 ? 535 SER A N 1 ATOM 3906 C CA . SER A 1 508 ? 97.354 -21.666 -49.546 1.00 268.57 ? 535 SER A CA 1 ATOM 3907 C C . SER A 1 508 ? 97.636 -22.435 -48.256 1.00 269.44 ? 535 SER A C 1 ATOM 3908 O O . SER A 1 508 ? 97.038 -22.156 -47.216 1.00 266.89 ? 535 SER A O 1 ATOM 3909 C CB . SER A 1 508 ? 98.652 -21.034 -50.058 1.00 269.11 ? 535 SER A CB 1 ATOM 3910 O OG . SER A 1 508 ? 99.585 -20.856 -49.007 1.00 269.71 ? 535 SER A OG 1 ATOM 3911 N N . GLU A 1 509 ? 98.542 -23.408 -48.328 1.00 272.11 ? 536 GLU A N 1 ATOM 3912 C CA . GLU A 1 509 ? 98.882 -24.209 -47.156 1.00 272.20 ? 536 GLU A CA 1 ATOM 3913 C C . GLU A 1 509 ? 99.710 -23.393 -46.171 1.00 273.70 ? 536 GLU A C 1 ATOM 3914 O O . GLU A 1 509 ? 99.695 -23.666 -44.972 1.00 271.28 ? 536 GLU A O 1 ATOM 3915 C CB . GLU A 1 509 ? 99.616 -25.503 -47.544 1.00 267.35 ? 536 GLU A CB 1 ATOM 3916 C CG . GLU A 1 509 ? 101.067 -25.354 -47.981 1.00 264.50 ? 536 GLU A CG 1 ATOM 3917 C CD . GLU A 1 509 ? 101.208 -24.883 -49.413 1.00 261.61 ? 536 GLU A CD 1 ATOM 3918 O OE1 . GLU A 1 509 ? 100.509 -25.434 -50.290 1.00 258.98 ? 536 GLU A OE1 1 ATOM 3919 O OE2 . GLU A 1 509 ? 102.028 -23.977 -49.665 1.00 257.34 ? 536 GLU A OE2 1 ATOM 3920 N N . THR A 1 510 ? 100.427 -22.386 -46.661 1.00 273.94 ? 537 THR A N 1 ATOM 3921 C CA . THR A 1 510 ? 101.228 -21.575 -45.758 1.00 265.63 ? 537 THR A CA 1 ATOM 3922 C C . THR A 1 510 ? 100.817 -20.104 -45.840 1.00 264.04 ? 537 THR A C 1 ATOM 3923 O O . THR A 1 510 ? 101.420 -19.249 -45.193 1.00 260.62 ? 537 THR A O 1 ATOM 3924 C CB . THR A 1 510 ? 102.734 -21.701 -46.070 1.00 259.18 ? 537 THR A CB 1 ATOM 3925 O OG1 . THR A 1 510 ? 102.971 -21.382 -47.446 1.00 261.08 ? 537 THR A OG1 1 ATOM 3926 C CG2 . THR A 1 510 ? 103.224 -23.117 -45.791 1.00 253.27 ? 537 THR A CG2 1 ATOM 3927 N N . SER A 1 511 ? 99.785 -19.815 -46.631 1.00 262.56 ? 538 SER A N 1 ATOM 3928 C CA . SER A 1 511 ? 99.292 -18.445 -46.779 1.00 254.96 ? 538 SER A CA 1 ATOM 3929 C C . SER A 1 511 ? 97.762 -18.397 -46.676 1.00 253.23 ? 538 SER A C 1 ATOM 3930 O O . SER A 1 511 ? 97.083 -19.345 -47.070 1.00 252.63 ? 538 SER A O 1 ATOM 3931 C CB . SER A 1 511 ? 99.762 -17.846 -48.105 1.00 247.81 ? 538 SER A CB 1 ATOM 3932 O OG . SER A 1 511 ? 101.118 -18.171 -48.361 1.00 242.02 ? 538 SER A OG 1 ATOM 3933 N N . ILE A 1 512 ? 97.227 -17.287 -46.168 1.00 251.41 ? 539 ILE A N 1 ATOM 3934 C CA . ILE A 1 512 ? 95.778 -17.090 -46.010 1.00 247.81 ? 539 ILE A CA 1 ATOM 3935 C C . ILE A 1 512 ? 95.369 -15.643 -46.326 1.00 253.37 ? 539 ILE A C 1 ATOM 3936 O O . ILE A 1 512 ? 96.016 -14.696 -45.879 1.00 252.88 ? 539 ILE A O 1 ATOM 3937 C CB . ILE A 1 512 ? 95.291 -17.514 -44.607 1.00 237.16 ? 539 ILE A CB 1 ATOM 3938 C CG1 . ILE A 1 512 ? 95.364 -19.037 -44.509 1.00 239.90 ? 539 ILE A CG1 1 ATOM 3939 C CG2 . ILE A 1 512 ? 93.840 -17.145 -44.401 1.00 240.19 ? 539 ILE A CG2 1 ATOM 3940 C CD1 . ILE A 1 512 ? 95.130 -19.597 -43.167 1.00 237.98 ? 539 ILE A CD1 1 ATOM 3941 N N . LEU A 1 513 ? 94.291 -15.485 -47.096 1.00 258.33 ? 540 LEU A N 1 ATOM 3942 C CA . LEU A 1 513 ? 93.788 -14.166 -47.494 1.00 257.95 ? 540 LEU A CA 1 ATOM 3943 C C . LEU A 1 513 ? 92.600 -13.671 -46.660 1.00 254.95 ? 540 LEU A C 1 ATOM 3944 O O . LEU A 1 513 ? 91.753 -14.456 -46.234 1.00 252.05 ? 540 LEU A O 1 ATOM 3945 C CB . LEU A 1 513 ? 93.381 -14.224 -48.973 1.00 251.90 ? 540 LEU A CB 1 ATOM 3946 C CG . LEU A 1 513 ? 93.355 -12.996 -49.885 1.00 243.15 ? 540 LEU A CG 1 ATOM 3947 C CD1 . LEU A 1 513 ? 93.410 -13.452 -51.334 1.00 237.29 ? 540 LEU A CD1 1 ATOM 3948 C CD2 . LEU A 1 513 ? 92.119 -12.140 -49.654 1.00 241.10 ? 540 LEU A CD2 1 ATOM 3949 N N . LEU A 1 514 ? 92.558 -12.356 -46.434 1.00 253.01 ? 541 LEU A N 1 ATOM 3950 C CA . LEU A 1 514 ? 91.494 -11.714 -45.656 1.00 247.67 ? 541 LEU A CA 1 ATOM 3951 C C . LEU A 1 514 ? 90.742 -10.584 -46.380 1.00 245.62 ? 541 LEU A C 1 ATOM 3952 O O . LEU A 1 514 ? 91.362 -9.663 -46.912 1.00 241.35 ? 541 LEU A O 1 ATOM 3953 C CB . LEU A 1 514 ? 92.075 -11.162 -44.353 1.00 241.02 ? 541 LEU A CB 1 ATOM 3954 C CG . LEU A 1 514 ? 91.034 -10.675 -43.348 1.00 238.44 ? 541 LEU A CG 1 ATOM 3955 C CD1 . LEU A 1 514 ? 90.219 -11.853 -42.850 1.00 237.61 ? 541 LEU A CD1 1 ATOM 3956 C CD2 . LEU A 1 514 ? 91.688 -9.937 -42.192 1.00 240.22 ? 541 LEU A CD2 1 ATOM 3957 N N . SER A 1 515 ? 89.412 -10.664 -46.400 1.00 246.46 ? 542 SER A N 1 ATOM 3958 C CA . SER A 1 515 ? 88.572 -9.649 -47.050 1.00 241.95 ? 542 SER A CA 1 ATOM 3959 C C . SER A 1 515 ? 87.718 -8.869 -46.034 1.00 238.01 ? 542 SER A C 1 ATOM 3960 O O . SER A 1 515 ? 86.873 -9.455 -45.356 1.00 230.76 ? 542 SER A O 1 ATOM 3961 C CB . SER A 1 515 ? 87.670 -10.295 -48.104 1.00 235.71 ? 542 SER A CB 1 ATOM 3962 O OG . SER A 1 515 ? 88.409 -10.653 -49.260 1.00 225.67 ? 542 SER A OG 1 ATOM 3963 N N . TRP A 1 516 ? 87.934 -7.557 -45.933 1.00 238.23 ? 543 TRP A N 1 ATOM 3964 C CA . TRP A 1 516 ? 87.180 -6.712 -44.998 1.00 232.00 ? 543 TRP A CA 1 ATOM 3965 C C . TRP A 1 516 ? 86.839 -5.359 -45.627 1.00 229.52 ? 543 TRP A C 1 ATOM 3966 O O . TRP A 1 516 ? 87.496 -4.933 -46.577 1.00 227.96 ? 543 TRP A O 1 ATOM 3967 C CB . TRP A 1 516 ? 87.990 -6.505 -43.713 1.00 230.97 ? 543 TRP A CB 1 ATOM 3968 C CG . TRP A 1 516 ? 89.100 -5.500 -43.861 1.00 234.98 ? 543 TRP A CG 1 ATOM 3969 C CD1 . TRP A 1 516 ? 88.982 -4.135 -43.900 1.00 233.09 ? 543 TRP A CD1 1 ATOM 3970 C CD2 . TRP A 1 516 ? 90.481 -5.785 -44.101 1.00 240.39 ? 543 TRP A CD2 1 ATOM 3971 N NE1 . TRP A 1 516 ? 90.212 -3.559 -44.091 1.00 238.37 ? 543 TRP A NE1 1 ATOM 3972 C CE2 . TRP A 1 516 ? 91.149 -4.549 -44.223 1.00 240.96 ? 543 TRP A CE2 1 ATOM 3973 C CE3 . TRP A 1 516 ? 91.224 -6.966 -44.200 1.00 241.78 ? 543 TRP A CE3 1 ATOM 3974 C CZ2 . TRP A 1 516 ? 92.523 -4.462 -44.440 1.00 242.88 ? 543 TRP A CZ2 1 ATOM 3975 C CZ3 . TRP A 1 516 ? 92.587 -6.877 -44.415 1.00 240.79 ? 543 TRP A CZ3 1 ATOM 3976 C CH2 . TRP A 1 516 ? 93.222 -5.634 -44.532 1.00 240.37 ? 543 TRP A CH2 1 ATOM 3977 N N . THR A 1 517 ? 85.819 -4.682 -45.101 1.00 231.44 ? 544 THR A N 1 ATOM 3978 C CA . THR A 1 517 ? 85.423 -3.376 -45.632 1.00 232.37 ? 544 THR A CA 1 ATOM 3979 C C . THR A 1 517 ? 85.659 -2.241 -44.631 1.00 232.45 ? 544 THR A C 1 ATOM 3980 O O . THR A 1 517 ? 85.050 -2.218 -43.566 1.00 226.21 ? 544 THR A O 1 ATOM 3981 C CB . THR A 1 517 ? 83.939 -3.361 -46.043 1.00 226.29 ? 544 THR A CB 1 ATOM 3982 O OG1 . THR A 1 517 ? 83.714 -4.340 -47.065 1.00 224.56 ? 544 THR A OG1 1 ATOM 3983 C CG2 . THR A 1 517 ? 83.546 -1.987 -46.569 1.00 223.50 ? 544 THR A CG2 1 ATOM 3984 N N . PRO A 1 518 ? 86.497 -1.260 -45.002 1.00 233.79 ? 545 PRO A N 1 ATOM 3985 C CA . PRO A 1 518 ? 86.805 -0.116 -44.132 1.00 233.95 ? 545 PRO A CA 1 ATOM 3986 C C . PRO A 1 518 ? 85.611 0.824 -43.963 1.00 241.29 ? 545 PRO A C 1 ATOM 3987 O O . PRO A 1 518 ? 84.890 1.062 -44.933 1.00 241.00 ? 545 PRO A O 1 ATOM 3988 C CB . PRO A 1 518 ? 87.959 0.579 -44.861 1.00 227.92 ? 545 PRO A CB 1 ATOM 3989 C CG . PRO A 1 518 ? 87.788 0.196 -46.286 1.00 220.61 ? 545 PRO A CG 1 ATOM 3990 C CD . PRO A 1 518 ? 87.249 -1.207 -46.267 1.00 229.93 ? 545 PRO A CD 1 ATOM 3991 N N . PRO A 1 519 ? 85.401 1.347 -42.742 1.00 246.82 ? 546 PRO A N 1 ATOM 3992 C CA . PRO A 1 519 ? 84.279 2.255 -42.468 1.00 250.74 ? 546 PRO A CA 1 ATOM 3993 C C . PRO A 1 519 ? 84.420 3.627 -43.133 1.00 254.13 ? 546 PRO A C 1 ATOM 3994 O O . PRO A 1 519 ? 85.386 3.869 -43.857 1.00 257.41 ? 546 PRO A O 1 ATOM 3995 C CB . PRO A 1 519 ? 84.308 2.390 -40.941 1.00 235.27 ? 546 PRO A CB 1 ATOM 3996 C CG . PRO A 1 519 ? 85.722 2.106 -40.565 1.00 234.84 ? 546 PRO A CG 1 ATOM 3997 C CD . PRO A 1 519 ? 86.177 1.048 -41.526 1.00 237.74 ? 546 PRO A CD 1 ATOM 3998 N N . ARG A 1 520 ? 83.454 4.509 -42.876 1.00 249.95 ? 547 ARG A N 1 ATOM 3999 C CA . ARG A 1 520 ? 83.434 5.860 -43.443 1.00 239.86 ? 547 ARG A CA 1 ATOM 4000 C C . ARG A 1 520 ? 84.688 6.685 -43.142 1.00 244.97 ? 547 ARG A C 1 ATOM 4001 O O . ARG A 1 520 ? 85.185 7.391 -44.020 1.00 245.63 ? 547 ARG A O 1 ATOM 4002 C CB . ARG A 1 520 ? 82.184 6.605 -42.960 1.00 223.90 ? 547 ARG A CB 1 ATOM 4003 C CG . ARG A 1 520 ? 81.961 7.951 -43.632 1.00 212.35 ? 547 ARG A CG 1 ATOM 4004 C CD . ARG A 1 520 ? 80.878 8.759 -42.930 1.00 201.55 ? 547 ARG A CD 1 ATOM 4005 N NE . ARG A 1 520 ? 81.090 8.864 -41.489 1.00 202.37 ? 547 ARG A NE 1 ATOM 4006 C CZ . ARG A 1 520 ? 80.175 9.309 -40.634 1.00 194.31 ? 547 ARG A CZ 1 ATOM 4007 N NH1 . ARG A 1 520 ? 78.984 9.691 -41.076 1.00 188.17 ? 547 ARG A NH1 1 ATOM 4008 N NH2 . ARG A 1 520 ? 80.447 9.373 -39.338 1.00 190.85 ? 547 ARG A NH2 1 ATOM 4009 N N . SER A 1 521 ? 85.169 6.614 -41.902 1.00 248.42 ? 548 SER A N 1 ATOM 4010 C CA . SER A 1 521 ? 86.364 7.341 -41.464 1.00 244.09 ? 548 SER A CA 1 ATOM 4011 C C . SER A 1 521 ? 87.511 7.193 -42.467 1.00 244.02 ? 548 SER A C 1 ATOM 4012 O O . SER A 1 521 ? 88.093 6.119 -42.590 1.00 238.19 ? 548 SER A O 1 ATOM 4013 C CB . SER A 1 521 ? 86.812 6.866 -40.079 1.00 236.10 ? 548 SER A CB 1 ATOM 4014 O OG . SER A 1 521 ? 85.844 7.182 -39.091 1.00 225.91 ? 548 SER A OG 1 ATOM 4015 N N . ASP A 1 522 ? 87.827 8.270 -43.183 1.00 246.94 ? 549 ASP A N 1 ATOM 4016 C CA . ASP A 1 522 ? 88.901 8.241 -44.176 1.00 241.80 ? 549 ASP A CA 1 ATOM 4017 C C . ASP A 1 522 ? 90.252 8.266 -43.478 1.00 240.01 ? 549 ASP A C 1 ATOM 4018 O O . ASP A 1 522 ? 91.200 7.620 -43.926 1.00 236.93 ? 549 ASP A O 1 ATOM 4019 C CB . ASP A 1 522 ? 88.802 9.416 -45.156 1.00 234.08 ? 549 ASP A CB 1 ATOM 4020 C CG . ASP A 1 522 ? 88.513 10.734 -44.466 1.00 233.00 ? 549 ASP A CG 1 ATOM 4021 O OD1 . ASP A 1 522 ? 87.362 10.942 -44.028 1.00 240.53 ? 549 ASP A OD1 1 ATOM 4022 O OD2 . ASP A 1 522 ? 89.441 11.564 -44.361 1.00 219.97 ? 549 ASP A OD2 1 ATOM 4023 N N . THR A 1 523 ? 90.340 9.016 -42.385 1.00 244.35 ? 550 THR A N 1 ATOM 4024 C CA . THR A 1 523 ? 91.587 9.107 -41.642 1.00 241.50 ? 550 THR A CA 1 ATOM 4025 C C . THR A 1 523 ? 91.798 7.790 -40.908 1.00 233.94 ? 550 THR A C 1 ATOM 4026 O O . THR A 1 523 ? 91.196 7.543 -39.861 1.00 226.48 ? 550 THR A O 1 ATOM 4027 C CB . THR A 1 523 ? 91.578 10.270 -40.625 1.00 234.69 ? 550 THR A CB 1 ATOM 4028 O OG1 . THR A 1 523 ? 90.353 10.253 -39.880 1.00 235.10 ? 550 THR A OG1 1 ATOM 4029 C CG2 . THR A 1 523 ? 91.723 11.610 -41.333 1.00 233.24 ? 550 THR A CG2 1 ATOM 4030 N N . ILE A 1 524 ? 92.661 6.945 -41.467 1.00 237.31 ? 551 ILE A N 1 ATOM 4031 C CA . ILE A 1 524 ? 92.957 5.648 -40.873 1.00 233.96 ? 551 ILE A CA 1 ATOM 4032 C C . ILE A 1 524 ? 94.454 5.395 -40.848 1.00 226.64 ? 551 ILE A C 1 ATOM 4033 O O . ILE A 1 524 ? 95.125 5.492 -41.876 1.00 223.49 ? 551 ILE A O 1 ATOM 4034 C CB . ILE A 1 524 ? 92.305 4.490 -41.669 1.00 234.15 ? 551 ILE A CB 1 ATOM 4035 C CG1 . ILE A 1 524 ? 90.794 4.673 -41.805 1.00 233.21 ? 551 ILE A CG1 1 ATOM 4036 C CG2 . ILE A 1 524 ? 92.646 3.144 -41.045 1.00 231.18 ? 551 ILE A CG2 1 ATOM 4037 C CD1 . ILE A 1 524 ? 90.176 3.759 -42.848 1.00 222.11 ? 551 ILE A CD1 1 ATOM 4038 N N . ALA A 1 525 ? 94.978 5.068 -39.673 1.00 221.95 ? 552 ALA A N 1 ATOM 4039 C CA . ALA A 1 525 ? 96.400 4.793 -39.548 1.00 219.93 ? 552 ALA A CA 1 ATOM 4040 C C . ALA A 1 525 ? 96.702 3.370 -40.003 1.00 222.07 ? 552 ALA A C 1 ATOM 4041 O O . ALA A 1 525 ? 97.549 3.148 -40.869 1.00 223.75 ? 552 ALA A O 1 ATOM 4042 C CB . ALA A 1 525 ? 96.863 5.006 -38.115 1.00 216.48 ? 552 ALA A CB 1 ATOM 4043 N N . SER A 1 526 ? 95.970 2.418 -39.422 1.00 221.25 ? 553 SER A N 1 ATOM 4044 C CA . SER A 1 526 ? 96.118 0.994 -39.720 1.00 221.93 ? 553 SER A CA 1 ATOM 4045 C C . SER A 1 526 ? 95.055 0.143 -39.017 1.00 225.38 ? 553 SER A C 1 ATOM 4046 O O . SER A 1 526 ? 94.191 0.662 -38.317 1.00 226.44 ? 553 SER A O 1 ATOM 4047 C CB . SER A 1 526 ? 97.515 0.503 -39.324 1.00 220.36 ? 553 SER A CB 1 ATOM 4048 O OG . SER A 1 526 ? 97.809 0.824 -37.977 1.00 222.62 ? 553 SER A OG 1 ATOM 4049 N N . TYR A 1 527 ? 95.108 -1.164 -39.254 1.00 228.90 ? 554 TYR A N 1 ATOM 4050 C CA . TYR A 1 527 ? 94.185 -2.139 -38.662 1.00 236.27 ? 554 TYR A CA 1 ATOM 4051 C C . TYR A 1 527 ? 94.973 -3.132 -37.800 1.00 242.47 ? 554 TYR A C 1 ATOM 4052 O O . TYR A 1 527 ? 96.140 -3.414 -38.071 1.00 243.28 ? 554 TYR A O 1 ATOM 4053 C CB . TYR A 1 527 ? 93.333 -2.846 -39.720 1.00 240.33 ? 554 TYR A CB 1 ATOM 4054 C CG . TYR A 1 527 ? 92.258 -1.953 -40.307 1.00 235.77 ? 554 TYR A CG 1 ATOM 4055 C CD1 . TYR A 1 527 ? 92.570 -0.936 -41.200 1.00 239.84 ? 554 TYR A CD1 1 ATOM 4056 C CD2 . TYR A 1 527 ? 90.927 -2.109 -39.932 1.00 225.99 ? 554 TYR A CD2 1 ATOM 4057 C CE1 . TYR A 1 527 ? 91.583 -0.116 -41.718 1.00 237.87 ? 554 TYR A CE1 1 ATOM 4058 C CE2 . TYR A 1 527 ? 89.936 -1.295 -40.444 1.00 221.53 ? 554 TYR A CE2 1 ATOM 4059 C CZ . TYR A 1 527 ? 90.271 -0.300 -41.336 1.00 232.58 ? 554 TYR A CZ 1 ATOM 4060 O OH . TYR A 1 527 ? 89.289 0.513 -41.851 1.00 231.54 ? 554 TYR A OH 1 ATOM 4061 N N . GLU A 1 528 ? 94.321 -3.649 -36.761 1.00 242.54 ? 555 GLU A N 1 ATOM 4062 C CA . GLU A 1 528 ? 94.939 -4.588 -35.822 1.00 241.15 ? 555 GLU A CA 1 ATOM 4063 C C . GLU A 1 528 ? 94.608 -6.061 -36.108 1.00 245.28 ? 555 GLU A C 1 ATOM 4064 O O . GLU A 1 528 ? 93.441 -6.454 -36.166 1.00 240.39 ? 555 GLU A O 1 ATOM 4065 C CB . GLU A 1 528 ? 94.474 -4.206 -34.413 1.00 236.20 ? 555 GLU A CB 1 ATOM 4066 C CG . GLU A 1 528 ? 95.406 -4.542 -33.278 1.00 236.87 ? 555 GLU A CG 1 ATOM 4067 C CD . GLU A 1 528 ? 94.817 -4.148 -31.933 1.00 232.69 ? 555 GLU A CD 1 ATOM 4068 O OE1 . GLU A 1 528 ? 93.719 -4.639 -31.597 1.00 227.98 ? 555 GLU A OE1 1 ATOM 4069 O OE2 . GLU A 1 528 ? 95.443 -3.334 -31.220 1.00 232.69 ? 555 GLU A OE2 1 ATOM 4070 N N . LEU A 1 529 ? 95.663 -6.863 -36.280 1.00 249.10 ? 556 LEU A N 1 ATOM 4071 C CA . LEU A 1 529 ? 95.560 -8.301 -36.577 1.00 257.15 ? 556 LEU A CA 1 ATOM 4072 C C . LEU A 1 529 ? 96.108 -9.253 -35.495 1.00 254.43 ? 556 LEU A C 1 ATOM 4073 O O . LEU A 1 529 ? 97.294 -9.590 -35.482 1.00 254.54 ? 556 LEU A O 1 ATOM 4074 C CB . LEU A 1 529 ? 96.236 -8.614 -37.920 1.00 262.06 ? 556 LEU A CB 1 ATOM 4075 C CG . LEU A 1 529 ? 96.479 -10.086 -38.299 1.00 255.38 ? 556 LEU A CG 1 ATOM 4076 C CD1 . LEU A 1 529 ? 95.182 -10.895 -38.252 1.00 243.63 ? 556 LEU A CD1 1 ATOM 4077 C CD2 . LEU A 1 529 ? 97.122 -10.191 -39.671 1.00 243.07 ? 556 LEU A CD2 1 ATOM 4078 N N . VAL A 1 530 ? 95.257 -9.617 -34.546 1.00 248.89 ? 557 VAL A N 1 ATOM 4079 C CA . VAL A 1 530 ? 95.634 -10.528 -33.469 1.00 242.90 ? 557 VAL A CA 1 ATOM 4080 C C . VAL A 1 530 ? 95.620 -11.980 -33.945 1.00 246.16 ? 557 VAL A C 1 ATOM 4081 O O . VAL A 1 530 ? 94.543 -12.542 -34.079 1.00 248.45 ? 557 VAL A O 1 ATOM 4082 C CB . VAL A 1 530 ? 94.654 -10.431 -32.282 1.00 233.59 ? 557 VAL A CB 1 ATOM 4083 C CG1 . VAL A 1 530 ? 95.014 -11.443 -31.203 1.00 228.49 ? 557 VAL A CG1 1 ATOM 4084 C CG2 . VAL A 1 530 ? 94.616 -9.036 -31.727 1.00 231.18 ? 557 VAL A CG2 1 ATOM 4085 N N . TYR A 1 531 ? 96.763 -12.613 -34.213 1.00 248.33 ? 558 TYR A N 1 ATOM 4086 C CA . TYR A 1 531 ? 96.648 -14.001 -34.658 1.00 251.06 ? 558 TYR A CA 1 ATOM 4087 C C . TYR A 1 531 ? 97.326 -14.898 -33.637 1.00 247.93 ? 558 TYR A C 1 ATOM 4088 O O . TYR A 1 531 ? 98.302 -14.497 -33.002 1.00 247.75 ? 558 TYR A O 1 ATOM 4089 C CB . TYR A 1 531 ? 97.316 -14.225 -36.022 1.00 252.96 ? 558 TYR A CB 1 ATOM 4090 C CG . TYR A 1 531 ? 98.830 -14.395 -35.959 1.00 258.80 ? 558 TYR A CG 1 ATOM 4091 C CD1 . TYR A 1 531 ? 99.691 -13.307 -36.006 1.00 256.21 ? 558 TYR A CD1 1 ATOM 4092 C CD2 . TYR A 1 531 ? 99.392 -15.668 -35.886 1.00 256.24 ? 558 TYR A CD2 1 ATOM 4093 C CE1 . TYR A 1 531 ? 101.074 -13.486 -35.953 1.00 252.69 ? 558 TYR A CE1 1 ATOM 4094 C CE2 . TYR A 1 531 ? 100.761 -15.854 -35.832 1.00 255.81 ? 558 TYR A CE2 1 ATOM 4095 C CZ . TYR A 1 531 ? 101.599 -14.761 -35.868 1.00 253.51 ? 558 TYR A CZ 1 ATOM 4096 O OH . TYR A 1 531 ? 102.962 -14.958 -35.816 1.00 238.79 ? 558 TYR A OH 1 ATOM 4097 N N . ARG A 1 532 ? 96.818 -16.117 -33.479 1.00 242.08 ? 559 ARG A N 1 ATOM 4098 C CA . ARG A 1 532 ? 97.408 -17.060 -32.533 1.00 237.22 ? 559 ARG A CA 1 ATOM 4099 C C . ARG A 1 532 ? 97.257 -18.486 -33.041 1.00 233.10 ? 559 ARG A C 1 ATOM 4100 O O . ARG A 1 532 ? 96.196 -18.843 -33.553 1.00 233.07 ? 559 ARG A O 1 ATOM 4101 C CB . ARG A 1 532 ? 96.733 -16.951 -31.156 1.00 234.35 ? 559 ARG A CB 1 ATOM 4102 C CG . ARG A 1 532 ? 96.342 -15.544 -30.710 1.00 231.04 ? 559 ARG A CG 1 ATOM 4103 C CD . ARG A 1 532 ? 95.748 -15.525 -29.314 1.00 220.39 ? 559 ARG A CD 1 ATOM 4104 N NE . ARG A 1 532 ? 94.458 -16.205 -29.260 1.00 217.21 ? 559 ARG A NE 1 ATOM 4105 C CZ . ARG A 1 532 ? 93.628 -16.147 -28.224 1.00 217.43 ? 559 ARG A CZ 1 ATOM 4106 N NH1 . ARG A 1 532 ? 93.953 -15.434 -27.156 1.00 217.18 ? 559 ARG A NH1 1 ATOM 4107 N NH2 . ARG A 1 532 ? 92.472 -16.799 -28.255 1.00 216.40 ? 559 ARG A NH2 1 ATOM 4108 N N . ASP A 1 533 ? 98.319 -19.281 -32.944 1.00 232.62 ? 560 ASP A N 1 ATOM 4109 C CA . ASP A 1 533 ? 98.263 -20.673 -33.375 1.00 232.58 ? 560 ASP A CA 1 ATOM 4110 C C . ASP A 1 533 ? 97.135 -21.316 -32.552 1.00 234.53 ? 560 ASP A C 1 ATOM 4111 O O . ASP A 1 533 ? 97.328 -21.613 -31.371 1.00 237.28 ? 560 ASP A O 1 ATOM 4112 C CB . ASP A 1 533 ? 99.613 -21.380 -33.187 1.00 225.20 ? 560 ASP A CB 1 ATOM 4113 C CG . ASP A 1 533 ? 99.480 -22.884 -32.975 1.00 217.47 ? 560 ASP A CG 1 ATOM 4114 O OD1 . ASP A 1 533 ? 98.559 -23.505 -33.548 1.00 209.77 ? 560 ASP A OD1 1 ATOM 4115 O OD2 . ASP A 1 533 ? 100.315 -23.447 -32.239 1.00 217.23 ? 560 ASP A OD2 1 ATOM 4116 N N . GLY A 1 534 ? 95.970 -21.528 -33.151 1.00 232.38 ? 561 GLY A N 1 ATOM 4117 C CA . GLY A 1 534 ? 94.850 -22.128 -32.441 1.00 229.31 ? 561 GLY A CA 1 ATOM 4118 C C . GLY A 1 534 ? 94.337 -21.397 -31.204 1.00 232.30 ? 561 GLY A C 1 ATOM 4119 O O . GLY A 1 534 ? 94.163 -20.178 -31.226 1.00 233.03 ? 561 GLY A O 1 ATOM 4120 N N . ASP A 1 535 ? 94.088 -22.144 -30.127 1.00 231.52 ? 562 ASP A N 1 ATOM 4121 C CA . ASP A 1 535 ? 93.574 -21.577 -28.870 1.00 229.76 ? 562 ASP A CA 1 ATOM 4122 C C . ASP A 1 535 ? 94.577 -21.187 -27.768 1.00 224.97 ? 562 ASP A C 1 ATOM 4123 O O . ASP A 1 535 ? 94.406 -20.162 -27.107 1.00 221.85 ? 562 ASP A O 1 ATOM 4124 C CB . ASP A 1 535 ? 92.568 -22.559 -28.261 1.00 229.51 ? 562 ASP A CB 1 ATOM 4125 C CG . ASP A 1 535 ? 91.510 -23.004 -29.254 1.00 232.40 ? 562 ASP A CG 1 ATOM 4126 O OD1 . ASP A 1 535 ? 91.283 -22.282 -30.248 1.00 230.00 ? 562 ASP A OD1 1 ATOM 4127 O OD2 . ASP A 1 535 ? 90.903 -24.075 -29.039 1.00 232.32 ? 562 ASP A OD2 1 ATOM 4128 N N . GLN A 1 536 ? 95.610 -22.000 -27.566 1.00 224.34 ? 563 GLN A N 1 ATOM 4129 C CA . GLN A 1 536 ? 96.619 -21.737 -26.532 1.00 226.65 ? 563 GLN A CA 1 ATOM 4130 C C . GLN A 1 536 ? 97.820 -20.931 -27.028 1.00 230.52 ? 563 GLN A C 1 ATOM 4131 O O . GLN A 1 536 ? 98.936 -21.092 -26.530 1.00 232.14 ? 563 GLN A O 1 ATOM 4132 C CB . GLN A 1 536 ? 97.099 -23.050 -25.903 1.00 227.08 ? 563 GLN A CB 1 ATOM 4133 C CG . GLN A 1 536 ? 97.922 -23.955 -26.807 1.00 226.04 ? 563 GLN A CG 1 ATOM 4134 C CD . GLN A 1 536 ? 98.824 -24.885 -26.013 1.00 218.70 ? 563 GLN A CD 1 ATOM 4135 O OE1 . GLN A 1 536 ? 98.598 -25.122 -24.826 1.00 215.22 ? 563 GLN A OE1 1 ATOM 4136 N NE2 . GLN A 1 536 ? 99.858 -25.406 -26.663 1.00 213.68 ? 563 GLN A NE2 1 ATOM 4137 N N . GLY A 1 537 ? 97.584 -20.037 -27.980 1.00 227.61 ? 564 GLY A N 1 ATOM 4138 C CA . GLY A 1 537 ? 98.655 -19.230 -28.532 1.00 226.03 ? 564 GLY A CA 1 ATOM 4139 C C . GLY A 1 537 ? 98.921 -17.905 -27.841 1.00 224.75 ? 564 GLY A C 1 ATOM 4140 O O . GLY A 1 537 ? 98.253 -17.532 -26.876 1.00 224.46 ? 564 GLY A O 1 ATOM 4141 N N . GLU A 1 538 ? 99.916 -17.196 -28.364 1.00 225.62 ? 565 GLU A N 1 ATOM 4142 C CA . GLU A 1 538 ? 100.352 -15.905 -27.847 1.00 227.04 ? 565 GLU A CA 1 ATOM 4143 C C . GLU A 1 538 ? 99.798 -14.779 -28.710 1.00 235.79 ? 565 GLU A C 1 ATOM 4144 O O . GLU A 1 538 ? 99.806 -14.857 -29.938 1.00 243.28 ? 565 GLU A O 1 ATOM 4145 C CB . GLU A 1 538 ? 101.881 -15.836 -27.784 1.00 219.87 ? 565 GLU A CB 1 ATOM 4146 C CG . GLU A 1 538 ? 102.490 -16.583 -26.603 1.00 212.09 ? 565 GLU A CG 1 ATOM 4147 C CD . GLU A 1 538 ? 102.426 -18.090 -26.766 1.00 207.13 ? 565 GLU A CD 1 ATOM 4148 O OE1 . GLU A 1 538 ? 102.304 -18.559 -27.918 1.00 204.14 ? 565 GLU A OE1 1 ATOM 4149 O OE2 . GLU A 1 538 ? 102.495 -18.806 -25.744 1.00 205.57 ? 565 GLU A OE2 1 ATOM 4150 N N . GLU A 1 539 ? 99.317 -13.731 -28.049 1.00 236.79 ? 566 GLU A N 1 ATOM 4151 C CA . GLU A 1 539 ? 98.728 -12.580 -28.723 1.00 233.98 ? 566 GLU A CA 1 ATOM 4152 C C . GLU A 1 539 ? 99.737 -11.626 -29.373 1.00 231.64 ? 566 GLU A C 1 ATOM 4153 O O . GLU A 1 539 ? 100.185 -10.657 -28.761 1.00 220.09 ? 566 GLU A O 1 ATOM 4154 C CB . GLU A 1 539 ? 97.879 -11.808 -27.705 1.00 224.96 ? 566 GLU A CB 1 ATOM 4155 C CG . GLU A 1 539 ? 96.779 -10.962 -28.293 1.00 222.20 ? 566 GLU A CG 1 ATOM 4156 C CD . GLU A 1 539 ? 95.413 -11.314 -27.736 1.00 218.34 ? 566 GLU A CD 1 ATOM 4157 O OE1 . GLU A 1 539 ? 95.022 -12.498 -27.818 1.00 216.53 ? 566 GLU A OE1 1 ATOM 4158 O OE2 . GLU A 1 539 ? 94.727 -10.405 -27.222 1.00 215.78 ? 566 GLU A OE2 1 ATOM 4159 N N . GLN A 1 540 ? 100.082 -11.929 -30.627 1.00 237.55 ? 567 GLN A N 1 ATOM 4160 C CA . GLN A 1 540 ? 101.026 -11.139 -31.422 1.00 236.63 ? 567 GLN A CA 1 ATOM 4161 C C . GLN A 1 540 ? 100.272 -10.190 -32.367 1.00 244.99 ? 567 GLN A C 1 ATOM 4162 O O . GLN A 1 540 ? 99.204 -10.539 -32.872 1.00 243.13 ? 567 GLN A O 1 ATOM 4163 C CB . GLN A 1 540 ? 101.956 -12.062 -32.217 1.00 222.10 ? 567 GLN A CB 1 ATOM 4164 C CG . GLN A 1 540 ? 102.925 -12.868 -31.358 1.00 206.65 ? 567 GLN A CG 1 ATOM 4165 C CD . GLN A 1 540 ? 103.924 -12.001 -30.616 1.00 196.91 ? 567 GLN A CD 1 ATOM 4166 O OE1 . GLN A 1 540 ? 104.678 -11.242 -31.224 1.00 200.68 ? 567 GLN A OE1 1 ATOM 4167 N NE2 . GLN A 1 540 ? 103.936 -12.112 -29.292 1.00 187.28 ? 567 GLN A NE2 1 ATOM 4168 N N . ARG A 1 541 ? 100.820 -8.998 -32.603 1.00 248.62 ? 568 ARG A N 1 ATOM 4169 C CA . ARG A 1 541 ? 100.182 -8.010 -33.485 1.00 242.60 ? 568 ARG A CA 1 ATOM 4170 C C . ARG A 1 541 ? 100.926 -7.766 -34.809 1.00 240.54 ? 568 ARG A C 1 ATOM 4171 O O . ARG A 1 541 ? 102.156 -7.717 -34.822 1.00 238.75 ? 568 ARG A O 1 ATOM 4172 C CB . ARG A 1 541 ? 100.059 -6.672 -32.750 1.00 236.19 ? 568 ARG A CB 1 ATOM 4173 C CG . ARG A 1 541 ? 99.053 -6.631 -31.612 1.00 221.64 ? 568 ARG A CG 1 ATOM 4174 C CD . ARG A 1 541 ? 97.669 -7.072 -32.032 1.00 224.89 ? 568 ARG A CD 1 ATOM 4175 N NE . ARG A 1 541 ? 96.650 -6.531 -31.136 1.00 222.72 ? 568 ARG A NE 1 ATOM 4176 C CZ . ARG A 1 541 ? 96.400 -6.990 -29.915 1.00 222.34 ? 568 ARG A CZ 1 ATOM 4177 N NH1 . ARG A 1 541 ? 97.091 -8.012 -29.434 1.00 225.22 ? 568 ARG A NH1 1 ATOM 4178 N NH2 . ARG A 1 541 ? 95.451 -6.430 -29.177 1.00 217.07 ? 568 ARG A NH2 1 ATOM 4179 N N . ILE A 1 542 ? 100.192 -7.611 -35.914 1.00 241.46 ? 569 ILE A N 1 ATOM 4180 C CA . ILE A 1 542 ? 100.824 -7.356 -37.216 1.00 246.86 ? 569 ILE A CA 1 ATOM 4181 C C . ILE A 1 542 ? 100.395 -5.989 -37.789 1.00 242.12 ? 569 ILE A C 1 ATOM 4182 O O . ILE A 1 542 ? 99.243 -5.580 -37.642 1.00 230.71 ? 569 ILE A O 1 ATOM 4183 C CB . ILE A 1 542 ? 100.500 -8.480 -38.230 1.00 251.86 ? 569 ILE A CB 1 ATOM 4184 C CG1 . ILE A 1 542 ? 100.775 -9.851 -37.608 1.00 240.45 ? 569 ILE A CG1 1 ATOM 4185 C CG2 . ILE A 1 542 ? 101.331 -8.330 -39.494 1.00 248.48 ? 569 ILE A CG2 1 ATOM 4186 C CD1 . ILE A 1 542 ? 100.422 -11.015 -38.507 1.00 231.78 ? 569 ILE A CD1 1 ATOM 4187 N N . THR A 1 543 ? 101.330 -5.296 -38.440 1.00 245.54 ? 570 THR A N 1 ATOM 4188 C CA . THR A 1 543 ? 101.090 -3.977 -39.046 1.00 242.02 ? 570 THR A CA 1 ATOM 4189 C C . THR A 1 543 ? 100.484 -3.978 -40.463 1.00 240.12 ? 570 THR A C 1 ATOM 4190 O O . THR A 1 543 ? 101.229 -4.037 -41.443 1.00 238.65 ? 570 THR A O 1 ATOM 4191 C CB . THR A 1 543 ? 102.406 -3.165 -39.098 1.00 234.06 ? 570 THR A CB 1 ATOM 4192 O OG1 . THR A 1 543 ? 103.023 -3.163 -37.804 1.00 230.13 ? 570 THR A OG1 1 ATOM 4193 C CG2 . THR A 1 543 ? 102.146 -1.728 -39.541 1.00 224.07 ? 570 THR A CG2 1 ATOM 4194 N N . ILE A 1 544 ? 99.158 -3.937 -40.592 1.00 240.08 ? 571 ILE A N 1 ATOM 4195 C CA . ILE A 1 544 ? 98.554 -3.927 -41.931 1.00 244.72 ? 571 ILE A CA 1 ATOM 4196 C C . ILE A 1 544 ? 98.298 -2.528 -42.526 1.00 238.20 ? 571 ILE A C 1 ATOM 4197 O O . ILE A 1 544 ? 98.042 -1.567 -41.800 1.00 230.83 ? 571 ILE A O 1 ATOM 4198 C CB . ILE A 1 544 ? 97.219 -4.695 -41.920 1.00 248.20 ? 571 ILE A CB 1 ATOM 4199 C CG1 . ILE A 1 544 ? 97.286 -5.852 -40.921 1.00 244.19 ? 571 ILE A CG1 1 ATOM 4200 C CG2 . ILE A 1 544 ? 96.893 -5.228 -43.301 1.00 250.67 ? 571 ILE A CG2 1 ATOM 4201 C CD1 . ILE A 1 544 ? 96.079 -6.760 -40.960 1.00 244.95 ? 571 ILE A CD1 1 ATOM 4202 N N . GLU A 1 545 ? 98.378 -2.433 -43.854 1.00 234.58 ? 572 GLU A N 1 ATOM 4203 C CA . GLU A 1 545 ? 98.149 -1.187 -44.592 1.00 219.74 ? 572 GLU A CA 1 ATOM 4204 C C . GLU A 1 545 ? 96.671 -0.791 -44.776 1.00 217.20 ? 572 GLU A C 1 ATOM 4205 O O . GLU A 1 545 ? 95.814 -1.657 -44.953 1.00 217.70 ? 572 GLU A O 1 ATOM 4206 C CB . GLU A 1 545 ? 98.834 -1.282 -45.960 1.00 213.69 ? 572 GLU A CB 1 ATOM 4207 C CG . GLU A 1 545 ? 98.190 -2.253 -46.937 1.00 221.85 ? 572 GLU A CG 1 ATOM 4208 C CD . GLU A 1 545 ? 99.065 -2.523 -48.147 1.00 218.19 ? 572 GLU A CD 1 ATOM 4209 O OE1 . GLU A 1 545 ? 99.488 -1.549 -48.805 1.00 219.23 ? 572 GLU A OE1 1 ATOM 4210 O OE2 . GLU A 1 545 ? 99.338 -3.707 -48.436 1.00 211.86 ? 572 GLU A OE2 1 ATOM 4211 N N . PRO A 1 546 ? 96.370 0.519 -44.723 1.00 214.63 ? 573 PRO A N 1 ATOM 4212 C CA . PRO A 1 546 ? 95.012 1.050 -44.907 1.00 210.52 ? 573 PRO A CA 1 ATOM 4213 C C . PRO A 1 546 ? 94.510 0.934 -46.352 1.00 215.93 ? 573 PRO A C 1 ATOM 4214 O O . PRO A 1 546 ? 94.589 1.907 -47.104 1.00 214.19 ? 573 PRO A O 1 ATOM 4215 C CB . PRO A 1 546 ? 95.151 2.516 -44.481 1.00 210.90 ? 573 PRO A CB 1 ATOM 4216 C CG . PRO A 1 546 ? 96.587 2.829 -44.700 1.00 221.70 ? 573 PRO A CG 1 ATOM 4217 C CD . PRO A 1 546 ? 97.284 1.573 -44.257 1.00 221.44 ? 573 PRO A CD 1 ATOM 4218 N N . GLY A 1 547 ? 94.005 -0.234 -46.733 1.00 224.46 ? 574 GLY A N 1 ATOM 4219 C CA . GLY A 1 547 ? 93.501 -0.441 -48.079 1.00 224.18 ? 574 GLY A CA 1 ATOM 4220 C C . GLY A 1 547 ? 92.179 -1.180 -48.040 1.00 237.93 ? 574 GLY A C 1 ATOM 4221 O O . GLY A 1 547 ? 91.266 -0.779 -47.317 1.00 239.04 ? 574 GLY A O 1 ATOM 4222 N N . THR A 1 548 ? 92.063 -2.254 -48.815 1.00 246.91 ? 575 THR A N 1 ATOM 4223 C CA . THR A 1 548 ? 90.823 -3.021 -48.832 1.00 249.87 ? 575 THR A CA 1 ATOM 4224 C C . THR A 1 548 ? 91.079 -4.495 -48.508 1.00 252.60 ? 575 THR A C 1 ATOM 4225 O O . THR A 1 548 ? 90.244 -5.150 -47.883 1.00 247.88 ? 575 THR A O 1 ATOM 4226 C CB . THR A 1 548 ? 90.101 -2.903 -50.195 1.00 251.53 ? 575 THR A CB 1 ATOM 4227 O OG1 . THR A 1 548 ? 88.971 -3.784 -50.221 1.00 244.68 ? 575 THR A OG1 1 ATOM 4228 C CG2 . THR A 1 548 ? 91.041 -3.250 -51.343 1.00 250.22 ? 575 THR A CG2 1 ATOM 4229 N N . SER A 1 549 ? 92.231 -5.011 -48.930 1.00 260.21 ? 576 SER A N 1 ATOM 4230 C CA . SER A 1 549 ? 92.591 -6.407 -48.679 1.00 260.08 ? 576 SER A CA 1 ATOM 4231 C C . SER A 1 549 ? 94.085 -6.549 -48.378 1.00 261.24 ? 576 SER A C 1 ATOM 4232 O O . SER A 1 549 ? 94.866 -5.640 -48.661 1.00 263.56 ? 576 SER A O 1 ATOM 4233 C CB . SER A 1 549 ? 92.207 -7.282 -49.875 1.00 255.26 ? 576 SER A CB 1 ATOM 4234 O OG . SER A 1 549 ? 92.971 -6.950 -51.021 1.00 253.50 ? 576 SER A OG 1 ATOM 4235 N N . TYR A 1 550 ? 94.482 -7.683 -47.804 1.00 257.14 ? 577 TYR A N 1 ATOM 4236 C CA . TYR A 1 550 ? 95.892 -7.909 -47.484 1.00 256.10 ? 577 TYR A CA 1 ATOM 4237 C C . TYR A 1 550 ? 96.261 -9.395 -47.564 1.00 257.78 ? 577 TYR A C 1 ATOM 4238 O O . TYR A 1 550 ? 95.428 -10.264 -47.303 1.00 254.21 ? 577 TYR A O 1 ATOM 4239 C CB . TYR A 1 550 ? 96.221 -7.346 -46.099 1.00 253.28 ? 577 TYR A CB 1 ATOM 4240 C CG . TYR A 1 550 ? 97.593 -7.725 -45.582 1.00 253.32 ? 577 TYR A CG 1 ATOM 4241 C CD1 . TYR A 1 550 ? 98.714 -6.984 -45.935 1.00 243.71 ? 577 TYR A CD1 1 ATOM 4242 C CD2 . TYR A 1 550 ? 97.766 -8.806 -44.725 1.00 257.93 ? 577 TYR A CD2 1 ATOM 4243 C CE1 . TYR A 1 550 ? 99.969 -7.318 -45.468 1.00 241.74 ? 577 TYR A CE1 1 ATOM 4244 C CE2 . TYR A 1 550 ? 99.019 -9.147 -44.251 1.00 254.70 ? 577 TYR A CE2 1 ATOM 4245 C CZ . TYR A 1 550 ? 100.116 -8.399 -44.625 1.00 246.13 ? 577 TYR A CZ 1 ATOM 4246 O OH . TYR A 1 550 ? 101.367 -8.731 -44.157 1.00 241.01 ? 577 TYR A OH 1 ATOM 4247 N N . ARG A 1 551 ? 97.514 -9.677 -47.916 1.00 258.10 ? 578 ARG A N 1 ATOM 4248 C CA . ARG A 1 551 ? 98.010 -11.051 -48.035 1.00 250.74 ? 578 ARG A CA 1 ATOM 4249 C C . ARG A 1 551 ? 99.001 -11.443 -46.940 1.00 248.40 ? 578 ARG A C 1 ATOM 4250 O O . ARG A 1 551 ? 100.111 -10.914 -46.882 1.00 243.33 ? 578 ARG A O 1 ATOM 4251 C CB . ARG A 1 551 ? 98.667 -11.264 -49.401 1.00 244.85 ? 578 ARG A CB 1 ATOM 4252 C CG . ARG A 1 551 ? 97.780 -11.953 -50.424 1.00 239.56 ? 578 ARG A CG 1 ATOM 4253 C CD . ARG A 1 551 ? 96.414 -11.302 -50.481 1.00 246.52 ? 578 ARG A CD 1 ATOM 4254 N NE . ARG A 1 551 ? 95.894 -11.220 -51.841 1.00 246.99 ? 578 ARG A NE 1 ATOM 4255 C CZ . ARG A 1 551 ? 94.850 -10.478 -52.193 1.00 243.34 ? 578 ARG A CZ 1 ATOM 4256 N NH1 . ARG A 1 551 ? 94.207 -9.761 -51.281 1.00 241.65 ? 578 ARG A NH1 1 ATOM 4257 N NH2 . ARG A 1 551 ? 94.442 -10.458 -53.454 1.00 243.47 ? 578 ARG A NH2 1 ATOM 4258 N N . LEU A 1 552 ? 98.598 -12.370 -46.076 1.00 250.53 ? 579 LEU A N 1 ATOM 4259 C CA . LEU A 1 552 ? 99.462 -12.827 -44.992 1.00 255.09 ? 579 LEU A CA 1 ATOM 4260 C C . LEU A 1 552 ? 100.167 -14.124 -45.391 1.00 257.56 ? 579 LEU A C 1 ATOM 4261 O O . LEU A 1 552 ? 99.544 -15.041 -45.925 1.00 258.86 ? 579 LEU A O 1 ATOM 4262 C CB . LEU A 1 552 ? 98.662 -13.031 -43.702 1.00 254.57 ? 579 LEU A CB 1 ATOM 4263 C CG . LEU A 1 552 ? 99.450 -13.488 -42.469 1.00 248.27 ? 579 LEU A CG 1 ATOM 4264 C CD1 . LEU A 1 552 ? 100.532 -12.480 -42.109 1.00 249.54 ? 579 LEU A CD1 1 ATOM 4265 C CD2 . LEU A 1 552 ? 98.523 -13.726 -41.285 1.00 237.33 ? 579 LEU A CD2 1 ATOM 4266 N N . GLN A 1 553 ? 101.467 -14.192 -45.123 1.00 256.80 ? 580 GLN A N 1 ATOM 4267 C CA . GLN A 1 553 ? 102.272 -15.367 -45.446 1.00 253.39 ? 580 GLN A CA 1 ATOM 4268 C C . GLN A 1 553 ? 103.062 -15.828 -44.224 1.00 257.00 ? 580 GLN A C 1 ATOM 4269 O O . GLN A 1 553 ? 103.204 -15.083 -43.255 1.00 259.80 ? 580 GLN A O 1 ATOM 4270 C CB . GLN A 1 553 ? 103.219 -15.080 -46.617 1.00 242.81 ? 580 GLN A CB 1 ATOM 4271 C CG . GLN A 1 553 ? 103.979 -13.767 -46.517 1.00 238.43 ? 580 GLN A CG 1 ATOM 4272 C CD . GLN A 1 553 ? 103.194 -12.591 -47.069 1.00 236.65 ? 580 GLN A CD 1 ATOM 4273 O OE1 . GLN A 1 553 ? 102.654 -12.654 -48.174 1.00 234.62 ? 580 GLN A OE1 1 ATOM 4274 N NE2 . GLN A 1 553 ? 103.125 -11.513 -46.298 1.00 233.64 ? 580 GLN A NE2 1 ATOM 4275 N N . GLY A 1 554 ? 103.570 -17.055 -44.269 1.00 256.02 ? 581 GLY A N 1 ATOM 4276 C CA . GLY A 1 554 ? 104.334 -17.589 -43.157 1.00 253.57 ? 581 GLY A CA 1 ATOM 4277 C C . GLY A 1 554 ? 103.476 -18.292 -42.122 1.00 253.76 ? 581 GLY A C 1 ATOM 4278 O O . GLY A 1 554 ? 103.412 -17.877 -40.965 1.00 248.00 ? 581 GLY A O 1 ATOM 4279 N N . LEU A 1 555 ? 102.809 -19.360 -42.547 1.00 261.89 ? 582 LEU A N 1 ATOM 4280 C CA . LEU A 1 555 ? 101.946 -20.134 -41.665 1.00 265.35 ? 582 LEU A CA 1 ATOM 4281 C C . LEU A 1 555 ? 102.250 -21.619 -41.841 1.00 264.02 ? 582 LEU A C 1 ATOM 4282 O O . LEU A 1 555 ? 102.983 -22.008 -42.750 1.00 265.92 ? 582 LEU A O 1 ATOM 4283 C CB . LEU A 1 555 ? 100.469 -19.844 -41.958 1.00 259.97 ? 582 LEU A CB 1 ATOM 4284 C CG . LEU A 1 555 ? 99.551 -19.434 -40.800 1.00 246.75 ? 582 LEU A CG 1 ATOM 4285 C CD1 . LEU A 1 555 ? 98.268 -18.821 -41.337 1.00 235.51 ? 582 LEU A CD1 1 ATOM 4286 C CD2 . LEU A 1 555 ? 99.233 -20.614 -39.894 1.00 240.78 ? 582 LEU A CD2 1 ATOM 4287 N N . LYS A 1 556 ? 101.688 -22.443 -40.965 1.00 259.57 ? 583 LYS A N 1 ATOM 4288 C CA . LYS A 1 556 ? 101.891 -23.886 -41.014 1.00 259.10 ? 583 LYS A CA 1 ATOM 4289 C C . LYS A 1 556 ? 100.731 -24.539 -41.749 1.00 268.81 ? 583 LYS A C 1 ATOM 4290 O O . LYS A 1 556 ? 99.595 -24.095 -41.619 1.00 270.31 ? 583 LYS A O 1 ATOM 4291 C CB . LYS A 1 556 ? 102.034 -24.459 -39.605 1.00 248.10 ? 583 LYS A CB 1 ATOM 4292 C CG . LYS A 1 556 ? 103.353 -24.105 -38.947 1.00 228.55 ? 583 LYS A CG 1 ATOM 4293 C CD . LYS A 1 556 ? 104.459 -25.027 -39.423 1.00 230.26 ? 583 LYS A CD 1 ATOM 4294 C CE . LYS A 1 556 ? 105.819 -24.523 -38.976 1.00 231.98 ? 583 LYS A CE 1 ATOM 4295 N NZ . LYS A 1 556 ? 106.123 -24.913 -37.573 1.00 238.32 ? 583 LYS A NZ 1 ATOM 4296 N N . PRO A 1 557 ? 101.007 -25.614 -42.505 1.00 272.46 ? 584 PRO A N 1 ATOM 4297 C CA . PRO A 1 557 ? 99.927 -26.278 -43.244 1.00 274.17 ? 584 PRO A CA 1 ATOM 4298 C C . PRO A 1 557 ? 98.940 -26.996 -42.331 1.00 276.15 ? 584 PRO A C 1 ATOM 4299 O O . PRO A 1 557 ? 99.298 -27.376 -41.215 1.00 272.23 ? 584 PRO A O 1 ATOM 4300 C CB . PRO A 1 557 ? 100.676 -27.277 -44.133 1.00 268.94 ? 584 PRO A CB 1 ATOM 4301 C CG . PRO A 1 557 ? 101.952 -27.542 -43.407 1.00 271.05 ? 584 PRO A CG 1 ATOM 4302 C CD . PRO A 1 557 ? 102.316 -26.246 -42.743 1.00 269.74 ? 584 PRO A CD 1 ATOM 4303 N N . ASN A 1 558 ? 97.718 -27.179 -42.833 1.00 278.10 ? 585 ASN A N 1 ATOM 4304 C CA . ASN A 1 558 ? 96.613 -27.836 -42.125 1.00 273.92 ? 585 ASN A CA 1 ATOM 4305 C C . ASN A 1 558 ? 96.550 -27.530 -40.624 1.00 270.28 ? 585 ASN A C 1 ATOM 4306 O O . ASN A 1 558 ? 96.478 -28.441 -39.799 1.00 270.27 ? 585 ASN A O 1 ATOM 4307 C CB . ASN A 1 558 ? 96.655 -29.357 -42.350 1.00 270.92 ? 585 ASN A CB 1 ATOM 4308 C CG . ASN A 1 558 ? 97.982 -29.983 -41.957 1.00 274.65 ? 585 ASN A CG 1 ATOM 4309 O OD1 . ASN A 1 558 ? 98.943 -29.964 -42.726 1.00 277.49 ? 585 ASN A OD1 1 ATOM 4310 N ND2 . ASN A 1 558 ? 98.037 -30.548 -40.757 1.00 270.83 ? 585 ASN A ND2 1 ATOM 4311 N N . SER A 1 559 ? 96.569 -26.241 -40.279 1.00 267.64 ? 586 SER A N 1 ATOM 4312 C CA . SER A 1 559 ? 96.514 -25.824 -38.878 1.00 257.21 ? 586 SER A CA 1 ATOM 4313 C C . SER A 1 559 ? 95.564 -24.644 -38.659 1.00 244.46 ? 586 SER A C 1 ATOM 4314 O O . SER A 1 559 ? 95.481 -23.730 -39.481 1.00 241.62 ? 586 SER A O 1 ATOM 4315 C CB . SER A 1 559 ? 97.912 -25.456 -38.374 1.00 253.50 ? 586 SER A CB 1 ATOM 4316 O OG . SER A 1 559 ? 98.101 -24.051 -38.361 1.00 244.67 ? 586 SER A OG 1 ATOM 4317 N N . LEU A 1 560 ? 94.854 -24.680 -37.534 1.00 241.26 ? 587 LEU A N 1 ATOM 4318 C CA . LEU A 1 560 ? 93.898 -23.639 -37.158 1.00 234.27 ? 587 LEU A CA 1 ATOM 4319 C C . LEU A 1 560 ? 94.524 -22.469 -36.402 1.00 233.98 ? 587 LEU A C 1 ATOM 4320 O O . LEU A 1 560 ? 95.362 -22.671 -35.524 1.00 232.84 ? 587 LEU A O 1 ATOM 4321 C CB . LEU A 1 560 ? 92.785 -24.246 -36.301 1.00 227.57 ? 587 LEU A CB 1 ATOM 4322 C CG . LEU A 1 560 ? 91.549 -23.378 -36.054 1.00 218.69 ? 587 LEU A CG 1 ATOM 4323 C CD1 . LEU A 1 560 ? 90.754 -23.177 -37.336 1.00 219.31 ? 587 LEU A CD1 1 ATOM 4324 C CD2 . LEU A 1 560 ? 90.680 -23.983 -34.962 1.00 208.05 ? 587 LEU A CD2 1 ATOM 4325 N N . TYR A 1 561 ? 94.133 -21.247 -36.755 1.00 235.40 ? 588 TYR A N 1 ATOM 4326 C CA . TYR A 1 561 ? 94.662 -20.064 -36.082 1.00 236.16 ? 588 TYR A CA 1 ATOM 4327 C C . TYR A 1 561 ? 93.579 -18.982 -35.946 1.00 236.10 ? 588 TYR A C 1 ATOM 4328 O O . TYR A 1 561 ? 93.009 -18.520 -36.936 1.00 232.16 ? 588 TYR A O 1 ATOM 4329 C CB . TYR A 1 561 ? 95.902 -19.532 -36.813 1.00 236.38 ? 588 TYR A CB 1 ATOM 4330 C CG . TYR A 1 561 ? 95.617 -18.627 -37.983 1.00 230.75 ? 588 TYR A CG 1 ATOM 4331 C CD1 . TYR A 1 561 ? 95.138 -19.140 -39.173 1.00 228.74 ? 588 TYR A CD1 1 ATOM 4332 C CD2 . TYR A 1 561 ? 95.846 -17.258 -37.902 1.00 229.87 ? 588 TYR A CD2 1 ATOM 4333 C CE1 . TYR A 1 561 ? 94.877 -18.321 -40.239 1.00 228.64 ? 588 TYR A CE1 1 ATOM 4334 C CE2 . TYR A 1 561 ? 95.590 -16.429 -38.976 1.00 232.98 ? 588 TYR A CE2 1 ATOM 4335 C CZ . TYR A 1 561 ? 95.109 -16.970 -40.146 1.00 233.08 ? 588 TYR A CZ 1 ATOM 4336 O OH . TYR A 1 561 ? 94.841 -16.166 -41.229 1.00 243.24 ? 588 TYR A OH 1 ATOM 4337 N N . TYR A 1 562 ? 93.266 -18.620 -34.706 1.00 237.77 ? 589 TYR A N 1 ATOM 4338 C CA . TYR A 1 562 ? 92.256 -17.601 -34.426 1.00 237.08 ? 589 TYR A CA 1 ATOM 4339 C C . TYR A 1 562 ? 92.790 -16.202 -34.765 1.00 244.41 ? 589 TYR A C 1 ATOM 4340 O O . TYR A 1 562 ? 93.998 -15.976 -34.761 1.00 249.58 ? 589 TYR A O 1 ATOM 4341 C CB . TYR A 1 562 ? 91.826 -17.711 -32.954 1.00 231.39 ? 589 TYR A CB 1 ATOM 4342 C CG . TYR A 1 562 ? 91.234 -16.471 -32.315 1.00 230.44 ? 589 TYR A CG 1 ATOM 4343 C CD1 . TYR A 1 562 ? 90.072 -15.887 -32.801 1.00 228.65 ? 589 TYR A CD1 1 ATOM 4344 C CD2 . TYR A 1 562 ? 91.835 -15.899 -31.203 1.00 228.84 ? 589 TYR A CD2 1 ATOM 4345 C CE1 . TYR A 1 562 ? 89.542 -14.757 -32.205 1.00 224.02 ? 589 TYR A CE1 1 ATOM 4346 C CE2 . TYR A 1 562 ? 91.309 -14.775 -30.600 1.00 228.91 ? 589 TYR A CE2 1 ATOM 4347 C CZ . TYR A 1 562 ? 90.160 -14.210 -31.103 1.00 224.16 ? 589 TYR A CZ 1 ATOM 4348 O OH . TYR A 1 562 ? 89.632 -13.087 -30.508 1.00 213.67 ? 589 TYR A OH 1 ATOM 4349 N N . PHE A 1 563 ? 91.884 -15.273 -35.060 1.00 245.18 ? 590 PHE A N 1 ATOM 4350 C CA . PHE A 1 563 ? 92.232 -13.891 -35.401 1.00 247.33 ? 590 PHE A CA 1 ATOM 4351 C C . PHE A 1 563 ? 91.131 -12.934 -34.927 1.00 248.03 ? 590 PHE A C 1 ATOM 4352 O O . PHE A 1 563 ? 89.948 -13.276 -34.947 1.00 243.53 ? 590 PHE A O 1 ATOM 4353 C CB . PHE A 1 563 ? 92.547 -13.687 -36.891 1.00 243.40 ? 590 PHE A CB 1 ATOM 4354 C CG . PHE A 1 563 ? 91.420 -13.995 -37.822 1.00 244.58 ? 590 PHE A CG 1 ATOM 4355 C CD1 . PHE A 1 563 ? 90.963 -15.286 -37.996 1.00 244.83 ? 590 PHE A CD1 1 ATOM 4356 C CD2 . PHE A 1 563 ? 90.801 -12.973 -38.516 1.00 240.13 ? 590 PHE A CD2 1 ATOM 4357 C CE1 . PHE A 1 563 ? 89.934 -15.549 -38.873 1.00 244.19 ? 590 PHE A CE1 1 ATOM 4358 C CE2 . PHE A 1 563 ? 89.766 -13.236 -39.374 1.00 236.12 ? 590 PHE A CE2 1 ATOM 4359 C CZ . PHE A 1 563 ? 89.323 -14.518 -39.541 1.00 237.47 ? 590 PHE A CZ 1 ATOM 4360 N N . ARG A 1 564 ? 91.531 -11.732 -34.513 1.00 253.08 ? 591 ARG A N 1 ATOM 4361 C CA . ARG A 1 564 ? 90.594 -10.728 -34.008 1.00 247.65 ? 591 ARG A CA 1 ATOM 4362 C C . ARG A 1 564 ? 91.034 -9.309 -34.363 1.00 248.41 ? 591 ARG A C 1 ATOM 4363 O O . ARG A 1 564 ? 92.109 -8.835 -33.992 1.00 242.73 ? 591 ARG A O 1 ATOM 4364 C CB . ARG A 1 564 ? 90.445 -10.862 -32.489 1.00 231.45 ? 591 ARG A CB 1 ATOM 4365 C CG . ARG A 1 564 ? 89.495 -9.860 -31.842 1.00 221.88 ? 591 ARG A CG 1 ATOM 4366 C CD . ARG A 1 564 ? 89.880 -9.578 -30.389 1.00 218.77 ? 591 ARG A CD 1 ATOM 4367 N NE . ARG A 1 564 ? 91.182 -8.932 -30.256 1.00 218.16 ? 591 ARG A NE 1 ATOM 4368 C CZ . ARG A 1 564 ? 91.362 -7.616 -30.190 1.00 215.34 ? 591 ARG A CZ 1 ATOM 4369 N NH1 . ARG A 1 564 ? 90.322 -6.798 -30.248 1.00 214.39 ? 591 ARG A NH1 1 ATOM 4370 N NH2 . ARG A 1 564 ? 92.585 -7.113 -30.068 1.00 210.89 ? 591 ARG A NH2 1 ATOM 4371 N N . LEU A 1 565 ? 90.132 -8.656 -35.090 1.00 251.97 ? 592 LEU A N 1 ATOM 4372 C CA . LEU A 1 565 ? 90.252 -7.298 -35.612 1.00 245.37 ? 592 LEU A CA 1 ATOM 4373 C C . LEU A 1 565 ? 89.628 -6.210 -34.747 1.00 235.07 ? 592 LEU A C 1 ATOM 4374 O O . LEU A 1 565 ? 88.674 -6.453 -34.024 1.00 228.70 ? 592 LEU A O 1 ATOM 4375 C CB . LEU A 1 565 ? 89.592 -7.254 -36.998 1.00 240.81 ? 592 LEU A CB 1 ATOM 4376 C CG . LEU A 1 565 ? 90.007 -6.293 -38.116 1.00 237.35 ? 592 LEU A CG 1 ATOM 4377 C CD1 . LEU A 1 565 ? 89.479 -6.822 -39.433 1.00 235.82 ? 592 LEU A CD1 1 ATOM 4378 C CD2 . LEU A 1 565 ? 89.467 -4.893 -37.882 1.00 228.07 ? 592 LEU A CD2 1 ATOM 4379 N N . SER A 1 566 ? 90.209 -5.017 -34.823 1.00 234.55 ? 593 SER A N 1 ATOM 4380 C CA . SER A 1 566 ? 89.761 -3.839 -34.086 1.00 229.92 ? 593 SER A CA 1 ATOM 4381 C C . SER A 1 566 ? 90.385 -2.633 -34.782 1.00 238.06 ? 593 SER A C 1 ATOM 4382 O O . SER A 1 566 ? 91.594 -2.417 -34.695 1.00 240.18 ? 593 SER A O 1 ATOM 4383 C CB . SER A 1 566 ? 90.169 -3.905 -32.612 1.00 217.18 ? 593 SER A CB 1 ATOM 4384 O OG . SER A 1 566 ? 91.570 -4.060 -32.466 1.00 217.60 ? 593 SER A OG 1 ATOM 4385 N N . ALA A 1 567 ? 89.548 -1.866 -35.484 1.00 236.20 ? 594 ALA A N 1 ATOM 4386 C CA . ALA A 1 567 ? 89.990 -0.679 -36.220 1.00 233.71 ? 594 ALA A CA 1 ATOM 4387 C C . ALA A 1 567 ? 90.871 0.256 -35.399 1.00 233.81 ? 594 ALA A C 1 ATOM 4388 O O . ALA A 1 567 ? 90.560 0.581 -34.253 1.00 228.99 ? 594 ALA A O 1 ATOM 4389 C CB . ALA A 1 567 ? 88.778 0.081 -36.750 1.00 219.18 ? 594 ALA A CB 1 ATOM 4390 N N . ARG A 1 568 ? 91.971 0.689 -36.008 1.00 233.74 ? 595 ARG A N 1 ATOM 4391 C CA . ARG A 1 568 ? 92.919 1.588 -35.360 1.00 229.45 ? 595 ARG A CA 1 ATOM 4392 C C . ARG A 1 568 ? 93.026 2.946 -36.060 1.00 229.89 ? 595 ARG A C 1 ATOM 4393 O O . ARG A 1 568 ? 93.452 3.040 -37.209 1.00 228.49 ? 595 ARG A O 1 ATOM 4394 C CB . ARG A 1 568 ? 94.286 0.905 -35.269 1.00 230.61 ? 595 ARG A CB 1 ATOM 4395 C CG . ARG A 1 568 ? 95.246 1.496 -34.257 1.00 233.41 ? 595 ARG A CG 1 ATOM 4396 C CD . ARG A 1 568 ? 96.673 1.169 -34.655 1.00 232.98 ? 595 ARG A CD 1 ATOM 4397 N NE . ARG A 1 568 ? 96.871 -0.278 -34.708 1.00 226.72 ? 595 ARG A NE 1 ATOM 4398 C CZ . ARG A 1 568 ? 97.982 -0.873 -35.129 1.00 218.48 ? 595 ARG A CZ 1 ATOM 4399 N NH1 . ARG A 1 568 ? 99.012 -0.147 -35.542 1.00 208.26 ? 595 ARG A NH1 1 ATOM 4400 N NH2 . ARG A 1 568 ? 98.063 -2.197 -35.139 1.00 217.89 ? 595 ARG A NH2 1 ATOM 4401 N N . SER A 1 569 ? 92.633 3.991 -35.346 1.00 231.64 ? 596 SER A N 1 ATOM 4402 C CA . SER A 1 569 ? 92.663 5.363 -35.846 1.00 235.78 ? 596 SER A CA 1 ATOM 4403 C C . SER A 1 569 ? 93.853 6.097 -35.236 1.00 238.31 ? 596 SER A C 1 ATOM 4404 O O . SER A 1 569 ? 94.317 5.727 -34.157 1.00 239.65 ? 596 SER A O 1 ATOM 4405 C CB . SER A 1 569 ? 91.354 6.086 -35.542 1.00 237.18 ? 596 SER A CB 1 ATOM 4406 O OG . SER A 1 569 ? 90.466 6.005 -36.644 1.00 233.08 ? 596 SER A OG 1 ATOM 4407 N N . PRO A 1 570 ? 94.366 7.135 -35.923 1.00 235.71 ? 597 PRO A N 1 ATOM 4408 C CA . PRO A 1 570 ? 95.518 7.839 -35.345 1.00 236.96 ? 597 PRO A CA 1 ATOM 4409 C C . PRO A 1 570 ? 95.185 8.638 -34.081 1.00 240.45 ? 597 PRO A C 1 ATOM 4410 O O . PRO A 1 570 ? 96.079 9.239 -33.486 1.00 240.83 ? 597 PRO A O 1 ATOM 4411 C CB . PRO A 1 570 ? 95.946 8.783 -36.475 1.00 226.52 ? 597 PRO A CB 1 ATOM 4412 C CG . PRO A 1 570 ? 94.705 8.996 -37.279 1.00 220.78 ? 597 PRO A CG 1 ATOM 4413 C CD . PRO A 1 570 ? 93.969 7.690 -37.230 1.00 228.14 ? 597 PRO A CD 1 ATOM 4414 N N . GLN A 1 571 ? 93.917 8.647 -33.685 1.00 241.55 ? 598 GLN A N 1 ATOM 4415 C CA . GLN A 1 571 ? 93.496 9.361 -32.487 1.00 233.52 ? 598 GLN A CA 1 ATOM 4416 C C . GLN A 1 571 ? 93.105 8.329 -31.413 1.00 228.65 ? 598 GLN A C 1 ATOM 4417 O O . GLN A 1 571 ? 93.171 8.615 -30.217 1.00 219.53 ? 598 GLN A O 1 ATOM 4418 C CB . GLN A 1 571 ? 92.366 10.350 -32.781 1.00 229.46 ? 598 GLN A CB 1 ATOM 4419 C CG . GLN A 1 571 ? 90.984 9.776 -32.715 1.00 228.90 ? 598 GLN A CG 1 ATOM 4420 C CD . GLN A 1 571 ? 90.488 9.272 -34.051 1.00 233.90 ? 598 GLN A CD 1 ATOM 4421 O OE1 . GLN A 1 571 ? 90.832 9.812 -35.101 1.00 238.35 ? 598 GLN A OE1 1 ATOM 4422 N NE2 . GLN A 1 571 ? 89.662 8.234 -34.017 1.00 230.18 ? 598 GLN A NE2 1 ATOM 4423 N N . GLY A 1 572 ? 92.701 7.133 -31.850 1.00 232.16 ? 599 GLY A N 1 ATOM 4424 C CA . GLY A 1 572 ? 92.306 6.064 -30.939 1.00 231.70 ? 599 GLY A CA 1 ATOM 4425 C C . GLY A 1 572 ? 91.660 4.833 -31.570 1.00 236.01 ? 599 GLY A C 1 ATOM 4426 O O . GLY A 1 572 ? 91.004 4.917 -32.607 1.00 232.07 ? 599 GLY A O 1 ATOM 4427 N N . LEU A 1 573 ? 91.848 3.686 -30.913 1.00 238.72 ? 600 LEU A N 1 ATOM 4428 C CA . LEU A 1 573 ? 91.324 2.381 -31.346 1.00 228.99 ? 600 LEU A CA 1 ATOM 4429 C C . LEU A 1 573 ? 89.792 2.278 -31.372 1.00 225.55 ? 600 LEU A C 1 ATOM 4430 O O . LEU A 1 573 ? 89.110 2.908 -30.570 1.00 225.95 ? 600 LEU A O 1 ATOM 4431 C CB . LEU A 1 573 ? 91.899 1.289 -30.438 1.00 214.04 ? 600 LEU A CB 1 ATOM 4432 C CG . LEU A 1 573 ? 91.738 -0.182 -30.830 1.00 207.31 ? 600 LEU A CG 1 ATOM 4433 C CD1 . LEU A 1 573 ? 92.650 -0.529 -31.996 1.00 211.21 ? 600 LEU A CD1 1 ATOM 4434 C CD2 . LEU A 1 573 ? 92.029 -1.074 -29.637 1.00 193.02 ? 600 LEU A CD2 1 ATOM 4435 N N . GLY A 1 574 ? 89.263 1.446 -32.272 1.00 220.69 ? 601 GLY A N 1 ATOM 4436 C CA . GLY A 1 574 ? 87.825 1.257 -32.408 1.00 210.65 ? 601 GLY A CA 1 ATOM 4437 C C . GLY A 1 574 ? 87.147 0.045 -31.780 1.00 195.41 ? 601 GLY A C 1 ATOM 4438 O O . GLY A 1 574 ? 87.424 -0.325 -30.638 1.00 188.92 ? 601 GLY A O 1 ATOM 4439 N N . ALA A 1 575 ? 86.252 -0.573 -32.551 1.00 195.45 ? 602 ALA A N 1 ATOM 4440 C CA . ALA A 1 575 ? 85.484 -1.751 -32.132 1.00 202.59 ? 602 ALA A CA 1 ATOM 4441 C C . ALA A 1 575 ? 85.946 -3.035 -32.824 1.00 214.32 ? 602 ALA A C 1 ATOM 4442 O O . ALA A 1 575 ? 86.522 -2.984 -33.911 1.00 212.31 ? 602 ALA A O 1 ATOM 4443 C CB . ALA A 1 575 ? 84.002 -1.524 -32.389 1.00 198.99 ? 602 ALA A CB 1 ATOM 4444 N N . SER A 1 576 ? 85.700 -4.184 -32.191 1.00 221.50 ? 603 SER A N 1 ATOM 4445 C CA . SER A 1 576 ? 86.113 -5.470 -32.761 1.00 218.34 ? 603 SER A CA 1 ATOM 4446 C C . SER A 1 576 ? 85.017 -6.320 -33.423 1.00 214.31 ? 603 SER A C 1 ATOM 4447 O O . SER A 1 576 ? 83.915 -6.464 -32.893 1.00 207.53 ? 603 SER A O 1 ATOM 4448 C CB . SER A 1 576 ? 86.771 -6.311 -31.661 1.00 209.49 ? 603 SER A CB 1 ATOM 4449 O OG . SER A 1 576 ? 87.923 -5.667 -31.147 1.00 203.28 ? 603 SER A OG 1 ATOM 4450 N N . THR A 1 577 ? 85.348 -6.873 -34.591 1.00 213.77 ? 604 THR A N 1 ATOM 4451 C CA . THR A 1 577 ? 84.442 -7.725 -35.373 1.00 209.61 ? 604 THR A CA 1 ATOM 4452 C C . THR A 1 577 ? 84.176 -9.122 -34.792 1.00 211.88 ? 604 THR A C 1 ATOM 4453 O O . THR A 1 577 ? 84.764 -9.513 -33.784 1.00 214.22 ? 604 THR A O 1 ATOM 4454 C CB . THR A 1 577 ? 84.968 -7.904 -36.811 1.00 204.44 ? 604 THR A CB 1 ATOM 4455 O OG1 . THR A 1 577 ? 86.348 -8.289 -36.771 1.00 209.19 ? 604 THR A OG1 1 ATOM 4456 C CG2 . THR A 1 577 ? 84.838 -6.609 -37.587 1.00 198.32 ? 604 THR A CG2 1 ATOM 4457 N N . ALA A 1 578 ? 83.283 -9.859 -35.455 1.00 213.12 ? 605 ALA A N 1 ATOM 4458 C CA . ALA A 1 578 ? 82.897 -11.224 -35.074 1.00 211.12 ? 605 ALA A CA 1 ATOM 4459 C C . ALA A 1 578 ? 84.044 -12.244 -35.142 1.00 220.29 ? 605 ALA A C 1 ATOM 4460 O O . ALA A 1 578 ? 84.842 -12.222 -36.080 1.00 224.60 ? 605 ALA A O 1 ATOM 4461 C CB . ALA A 1 578 ? 81.739 -11.693 -35.944 1.00 203.34 ? 605 ALA A CB 1 ATOM 4462 N N . GLU A 1 579 ? 84.119 -13.132 -34.150 1.00 223.66 ? 606 GLU A N 1 ATOM 4463 C CA . GLU A 1 579 ? 85.163 -14.164 -34.097 1.00 228.35 ? 606 GLU A CA 1 ATOM 4464 C C . GLU A 1 579 ? 85.122 -15.255 -35.179 1.00 230.71 ? 606 GLU A C 1 ATOM 4465 O O . GLU A 1 579 ? 84.298 -16.169 -35.123 1.00 228.33 ? 606 GLU A O 1 ATOM 4466 C CB . GLU A 1 579 ? 85.141 -14.850 -32.730 1.00 225.04 ? 606 GLU A CB 1 ATOM 4467 C CG . GLU A 1 579 ? 86.389 -15.663 -32.464 1.00 219.62 ? 606 GLU A CG 1 ATOM 4468 C CD . GLU A 1 579 ? 86.681 -15.844 -30.989 1.00 217.18 ? 606 GLU A CD 1 ATOM 4469 O OE1 . GLU A 1 579 ? 86.877 -14.825 -30.294 1.00 214.78 ? 606 GLU A OE1 1 ATOM 4470 O OE2 . GLU A 1 579 ? 86.733 -17.004 -30.530 1.00 218.63 ? 606 GLU A OE2 1 ATOM 4471 N N . ILE A 1 580 ? 86.018 -15.147 -36.153 1.00 239.95 ? 607 ILE A N 1 ATOM 4472 C CA . ILE A 1 580 ? 86.135 -16.102 -37.256 1.00 239.57 ? 607 ILE A CA 1 ATOM 4473 C C . ILE A 1 580 ? 87.470 -16.853 -37.190 1.00 239.98 ? 607 ILE A C 1 ATOM 4474 O O . ILE A 1 580 ? 88.424 -16.336 -36.616 1.00 239.67 ? 607 ILE A O 1 ATOM 4475 C CB . ILE A 1 580 ? 85.997 -15.399 -38.617 1.00 232.17 ? 607 ILE A CB 1 ATOM 4476 C CG1 . ILE A 1 580 ? 84.789 -14.469 -38.595 1.00 220.06 ? 607 ILE A CG1 1 ATOM 4477 C CG2 . ILE A 1 580 ? 85.863 -16.411 -39.752 1.00 223.60 ? 607 ILE A CG2 1 ATOM 4478 C CD1 . ILE A 1 580 ? 84.815 -13.452 -39.676 1.00 210.32 ? 607 ILE A CD1 1 ATOM 4479 N N . SER A 1 581 ? 87.522 -18.098 -37.663 1.00 233.57 ? 608 SER A N 1 ATOM 4480 C CA . SER A 1 581 ? 88.780 -18.849 -37.654 1.00 223.68 ? 608 SER A CA 1 ATOM 4481 C C . SER A 1 581 ? 88.995 -19.478 -39.037 1.00 227.98 ? 608 SER A C 1 ATOM 4482 O O . SER A 1 581 ? 88.028 -19.881 -39.683 1.00 227.06 ? 608 SER A O 1 ATOM 4483 C CB . SER A 1 581 ? 88.777 -19.922 -36.565 1.00 206.80 ? 608 SER A CB 1 ATOM 4484 O OG . SER A 1 581 ? 88.580 -19.347 -35.286 1.00 195.39 ? 608 SER A OG 1 ATOM 4485 N N . ALA A 1 582 ? 90.244 -19.568 -39.498 1.00 228.80 ? 609 ALA A N 1 ATOM 4486 C CA . ALA A 1 582 ? 90.502 -20.170 -40.809 1.00 225.66 ? 609 ALA A CA 1 ATOM 4487 C C . ALA A 1 582 ? 91.537 -21.298 -40.756 1.00 230.19 ? 609 ALA A C 1 ATOM 4488 O O . ALA A 1 582 ? 92.526 -21.209 -40.028 1.00 232.07 ? 609 ALA A O 1 ATOM 4489 C CB . ALA A 1 582 ? 90.950 -19.098 -41.794 1.00 221.74 ? 609 ALA A CB 1 ATOM 4490 N N . ARG A 1 583 ? 91.305 -22.351 -41.537 1.00 230.90 ? 610 ARG A N 1 ATOM 4491 C CA . ARG A 1 583 ? 92.212 -23.500 -41.591 1.00 234.06 ? 610 ARG A CA 1 ATOM 4492 C C . ARG A 1 583 ? 93.161 -23.525 -42.794 1.00 240.07 ? 610 ARG A C 1 ATOM 4493 O O . ARG A 1 583 ? 92.708 -23.441 -43.934 1.00 239.07 ? 610 ARG A O 1 ATOM 4494 C CB . ARG A 1 583 ? 91.406 -24.801 -41.574 1.00 230.17 ? 610 ARG A CB 1 ATOM 4495 C CG . ARG A 1 583 ? 92.254 -26.041 -41.807 1.00 229.89 ? 610 ARG A CG 1 ATOM 4496 C CD . ARG A 1 583 ? 91.425 -27.313 -41.770 1.00 225.71 ? 610 ARG A CD 1 ATOM 4497 N NE . ARG A 1 583 ? 90.418 -27.345 -42.827 1.00 221.85 ? 610 ARG A NE 1 ATOM 4498 C CZ . ARG A 1 583 ? 89.485 -28.285 -42.939 1.00 211.48 ? 610 ARG A CZ 1 ATOM 4499 N NH1 . ARG A 1 583 ? 89.432 -29.276 -42.059 1.00 219.43 ? 610 ARG A NH1 1 ATOM 4500 N NH2 . ARG A 1 583 ? 88.607 -28.239 -43.932 1.00 188.78 ? 610 ARG A NH2 1 ATOM 4501 N N . THR A 1 584 ? 94.463 -23.655 -42.549 1.00 247.94 ? 611 THR A N 1 ATOM 4502 C CA . THR A 1 584 ? 95.442 -23.710 -43.636 1.00 254.66 ? 611 THR A CA 1 ATOM 4503 C C . THR A 1 584 ? 95.218 -25.000 -44.432 1.00 262.98 ? 611 THR A C 1 ATOM 4504 O O . THR A 1 584 ? 94.647 -25.953 -43.905 1.00 263.95 ? 611 THR A O 1 ATOM 4505 C CB . THR A 1 584 ? 96.895 -23.667 -43.125 1.00 258.94 ? 611 THR A CB 1 ATOM 4506 O OG1 . THR A 1 584 ? 97.008 -24.442 -41.925 1.00 267.67 ? 611 THR A OG1 1 ATOM 4507 C CG2 . THR A 1 584 ? 97.330 -22.243 -42.837 1.00 246.20 ? 611 THR A CG2 1 ATOM 4508 N N . MET A 1 585 ? 95.650 -25.036 -45.691 1.00 266.66 ? 612 MET A N 1 ATOM 4509 C CA . MET A 1 585 ? 95.476 -26.239 -46.511 1.00 265.95 ? 612 MET A CA 1 ATOM 4510 C C . MET A 1 585 ? 96.198 -27.439 -45.899 1.00 263.58 ? 612 MET A C 1 ATOM 4511 O O . MET A 1 585 ? 97.400 -27.620 -46.096 1.00 258.72 ? 612 MET A O 1 ATOM 4512 C CB . MET A 1 585 ? 95.981 -26.013 -47.936 1.00 261.68 ? 612 MET A CB 1 ATOM 4513 C CG . MET A 1 585 ? 95.329 -24.856 -48.664 1.00 260.18 ? 612 MET A CG 1 ATOM 4514 S SD . MET A 1 585 ? 95.307 -25.109 -50.447 1.00 252.42 ? 612 MET A SD 1 ATOM 4515 C CE . MET A 1 585 ? 94.165 -23.828 -50.956 1.00 255.05 ? 612 MET A CE 1 ATOM 4516 N N . CYS B 2 20 ? -26.000 -29.039 -27.407 1.00 109.63 ? 31 CYS B N 1 ATOM 4517 C CA . CYS B 2 20 ? -26.211 -29.381 -28.808 1.00 103.43 ? 31 CYS B CA 1 ATOM 4518 C C . CYS B 2 20 ? -27.714 -29.556 -29.063 1.00 107.80 ? 31 CYS B C 1 ATOM 4519 O O . CYS B 2 20 ? -28.326 -30.509 -28.579 1.00 122.45 ? 31 CYS B O 1 ATOM 4520 C CB . CYS B 2 20 ? -25.434 -30.656 -29.151 1.00 104.38 ? 31 CYS B CB 1 ATOM 4521 S SG . CYS B 2 20 ? -25.125 -30.959 -30.904 1.00 106.13 ? 31 CYS B SG 1 ATOM 4522 N N . THR B 2 21 ? -28.294 -28.641 -29.839 1.00 103.85 ? 32 THR B N 1 ATOM 4523 C CA . THR B 2 21 ? -29.726 -28.647 -30.162 1.00 107.78 ? 32 THR B CA 1 ATOM 4524 C C . THR B 2 21 ? -30.242 -29.770 -31.077 1.00 107.62 ? 32 THR B C 1 ATOM 4525 O O . THR B 2 21 ? -30.039 -29.741 -32.289 1.00 107.69 ? 32 THR B O 1 ATOM 4526 C CB . THR B 2 21 ? -30.133 -27.296 -30.807 1.00 105.09 ? 32 THR B CB 1 ATOM 4527 O OG1 . THR B 2 21 ? -29.869 -27.333 -32.214 1.00 112.10 ? 32 THR B OG1 1 ATOM 4528 C CG2 . THR B 2 21 ? -29.351 -26.150 -30.187 1.00 100.59 ? 32 THR B CG2 1 ATOM 4529 N N . ASP B 2 22 ? -30.906 -30.759 -30.484 1.00 101.46 ? 33 ASP B N 1 ATOM 4530 C CA . ASP B 2 22 ? -31.363 -31.951 -31.203 1.00 90.56 ? 33 ASP B CA 1 ATOM 4531 C C . ASP B 2 22 ? -32.796 -31.715 -31.701 1.00 90.62 ? 33 ASP B C 1 ATOM 4532 O O . ASP B 2 22 ? -33.661 -31.299 -30.931 1.00 93.19 ? 33 ASP B O 1 ATOM 4533 C CB . ASP B 2 22 ? -31.282 -33.199 -30.313 1.00 93.22 ? 33 ASP B CB 1 ATOM 4534 C CG . ASP B 2 22 ? -31.601 -34.492 -31.063 1.00 89.68 ? 33 ASP B CG 1 ATOM 4535 O OD1 . ASP B 2 22 ? -32.444 -34.484 -31.981 1.00 92.08 ? 33 ASP B OD1 1 ATOM 4536 O OD2 . ASP B 2 22 ? -31.002 -35.534 -30.726 1.00 89.56 ? 33 ASP B OD2 1 ATOM 4537 N N . TRP B 2 23 ? -33.039 -31.976 -32.983 1.00 93.14 ? 34 TRP B N 1 ATOM 4538 C CA . TRP B 2 23 ? -34.361 -31.790 -33.585 1.00 90.45 ? 34 TRP B CA 1 ATOM 4539 C C . TRP B 2 23 ? -35.163 -33.093 -33.681 1.00 93.94 ? 34 TRP B C 1 ATOM 4540 O O . TRP B 2 23 ? -36.266 -33.107 -34.232 1.00 89.98 ? 34 TRP B O 1 ATOM 4541 C CB . TRP B 2 23 ? -34.209 -31.197 -34.991 1.00 88.16 ? 34 TRP B CB 1 ATOM 4542 C CG . TRP B 2 23 ? -33.971 -29.718 -35.040 1.00 81.75 ? 34 TRP B CG 1 ATOM 4543 C CD1 . TRP B 2 23 ? -32.772 -29.088 -35.206 1.00 86.17 ? 34 TRP B CD1 1 ATOM 4544 C CD2 . TRP B 2 23 ? -34.965 -28.688 -35.009 1.00 76.70 ? 34 TRP B CD2 1 ATOM 4545 N NE1 . TRP B 2 23 ? -32.951 -27.728 -35.235 1.00 81.54 ? 34 TRP B NE1 1 ATOM 4546 C CE2 . TRP B 2 23 ? -34.289 -27.454 -35.122 1.00 70.08 ? 34 TRP B CE2 1 ATOM 4547 C CE3 . TRP B 2 23 ? -36.359 -28.687 -34.880 1.00 82.98 ? 34 TRP B CE3 1 ATOM 4548 C CZ2 . TRP B 2 23 ? -34.960 -26.231 -35.110 1.00 64.17 ? 34 TRP B CZ2 1 ATOM 4549 C CZ3 . TRP B 2 23 ? -37.022 -27.472 -34.868 1.00 89.19 ? 34 TRP B CZ3 1 ATOM 4550 C CH2 . TRP B 2 23 ? -36.322 -26.262 -34.982 1.00 78.90 ? 34 TRP B CH2 1 ATOM 4551 N N . SER B 2 24 ? -34.604 -34.172 -33.137 1.00 98.06 ? 35 SER B N 1 ATOM 4552 C CA . SER B 2 24 ? -35.199 -35.515 -33.185 1.00 102.19 ? 35 SER B CA 1 ATOM 4553 C C . SER B 2 24 ? -35.442 -35.980 -34.634 1.00 108.52 ? 35 SER B C 1 ATOM 4554 O O . SER B 2 24 ? -34.917 -35.388 -35.573 1.00 110.19 ? 35 SER B O 1 ATOM 4555 C CB . SER B 2 24 ? -36.501 -35.561 -32.376 1.00 104.83 ? 35 SER B CB 1 ATOM 4556 O OG . SER B 2 24 ? -36.782 -36.880 -31.945 1.00 112.81 ? 35 SER B OG 1 ATOM 4557 N N . VAL B 2 25 ? -36.220 -37.048 -34.803 1.00 109.47 ? 36 VAL B N 1 ATOM 4558 C CA . VAL B 2 25 ? -36.515 -37.621 -36.125 1.00 99.73 ? 36 VAL B CA 1 ATOM 4559 C C . VAL B 2 25 ? -37.218 -36.662 -37.092 1.00 101.20 ? 36 VAL B C 1 ATOM 4560 O O . VAL B 2 25 ? -38.218 -36.048 -36.738 1.00 102.38 ? 36 VAL B O 1 ATOM 4561 C CB . VAL B 2 25 ? -37.376 -38.897 -35.990 1.00 96.95 ? 36 VAL B CB 1 ATOM 4562 C CG1 . VAL B 2 25 ? -37.761 -39.441 -37.358 1.00 90.73 ? 36 VAL B CG1 1 ATOM 4563 C CG2 . VAL B 2 25 ? -36.639 -39.949 -35.172 1.00 104.25 ? 36 VAL B CG2 1 ATOM 4564 N N . ASP B 2 26 ? -36.703 -36.553 -38.316 1.00 102.44 ? 37 ASP B N 1 ATOM 4565 C CA . ASP B 2 26 ? -37.281 -35.665 -39.328 1.00 102.58 ? 37 ASP B CA 1 ATOM 4566 C C . ASP B 2 26 ? -38.557 -36.246 -39.943 1.00 106.34 ? 37 ASP B C 1 ATOM 4567 O O . ASP B 2 26 ? -38.738 -37.463 -39.965 1.00 114.18 ? 37 ASP B O 1 ATOM 4568 C CB . ASP B 2 26 ? -36.248 -35.396 -40.431 1.00 97.61 ? 37 ASP B CB 1 ATOM 4569 C CG . ASP B 2 26 ? -36.804 -34.567 -41.574 1.00 95.69 ? 37 ASP B CG 1 ATOM 4570 O OD1 . ASP B 2 26 ? -37.154 -33.395 -41.344 1.00 97.26 ? 37 ASP B OD1 1 ATOM 4571 O OD2 . ASP B 2 26 ? -36.890 -35.092 -42.704 1.00 94.96 ? 37 ASP B OD2 1 ATOM 4572 N N . ILE B 2 27 ? -39.446 -35.368 -40.409 1.00 99.51 ? 38 ILE B N 1 ATOM 4573 C CA . ILE B 2 27 ? -40.722 -35.770 -41.016 1.00 100.48 ? 38 ILE B CA 1 ATOM 4574 C C . ILE B 2 27 ? -40.542 -36.759 -42.172 1.00 102.33 ? 38 ILE B C 1 ATOM 4575 O O . ILE B 2 27 ? -41.229 -37.776 -42.247 1.00 100.44 ? 38 ILE B O 1 ATOM 4576 C CB . ILE B 2 27 ? -41.561 -34.555 -41.510 1.00 102.73 ? 38 ILE B CB 1 ATOM 4577 C CG1 . ILE B 2 27 ? -42.869 -35.051 -42.133 1.00 104.44 ? 38 ILE B CG1 1 ATOM 4578 C CG2 . ILE B 2 27 ? -40.818 -33.725 -42.537 1.00 106.51 ? 38 ILE B CG2 1 ATOM 4579 C CD1 . ILE B 2 27 ? -43.670 -33.974 -42.829 1.00 107.99 ? 38 ILE B CD1 1 ATOM 4580 N N . LYS B 2 28 ? -39.635 -36.432 -43.088 1.00 101.16 ? 39 LYS B N 1 ATOM 4581 C CA . LYS B 2 28 ? -39.397 -37.247 -44.268 1.00 94.89 ? 39 LYS B CA 1 ATOM 4582 C C . LYS B 2 28 ? -38.701 -38.554 -43.930 1.00 94.55 ? 39 LYS B C 1 ATOM 4583 O O . LYS B 2 28 ? -37.551 -38.575 -43.486 1.00 88.52 ? 39 LYS B O 1 ATOM 4584 C CB . LYS B 2 28 ? -38.577 -36.459 -45.295 1.00 94.13 ? 39 LYS B CB 1 ATOM 4585 C CG . LYS B 2 28 ? -38.234 -37.231 -46.558 1.00 101.93 ? 39 LYS B CG 1 ATOM 4586 C CD . LYS B 2 28 ? -37.740 -36.286 -47.648 1.00 116.45 ? 39 LYS B CD 1 ATOM 4587 C CE . LYS B 2 28 ? -37.392 -37.022 -48.935 1.00 109.46 ? 39 LYS B CE 1 ATOM 4588 N NZ . LYS B 2 28 ? -36.512 -36.193 -49.808 1.00 107.36 ? 39 LYS B NZ 1 ATOM 4589 N N . LYS B 2 29 ? -39.421 -39.645 -44.160 1.00 104.60 ? 40 LYS B N 1 ATOM 4590 C CA . LYS B 2 29 ? -38.904 -40.981 -43.930 1.00 110.15 ? 40 LYS B CA 1 ATOM 4591 C C . LYS B 2 29 ? -38.344 -41.538 -45.235 1.00 111.64 ? 40 LYS B C 1 ATOM 4592 O O . LYS B 2 29 ? -38.734 -41.116 -46.325 1.00 112.63 ? 40 LYS B O 1 ATOM 4593 C CB . LYS B 2 29 ? -39.996 -41.921 -43.397 1.00 112.82 ? 40 LYS B CB 1 ATOM 4594 C CG . LYS B 2 29 ? -39.873 -42.340 -41.932 1.00 105.37 ? 40 LYS B CG 1 ATOM 4595 C CD . LYS B 2 29 ? -41.079 -41.909 -41.093 1.00 91.99 ? 40 LYS B CD 1 ATOM 4596 C CE . LYS B 2 29 ? -40.992 -40.465 -40.644 1.00 91.87 ? 40 LYS B CE 1 ATOM 4597 N NZ . LYS B 2 29 ? -41.590 -40.273 -39.296 1.00 81.66 ? 40 LYS B NZ 1 ATOM 4598 N N . TYR B 2 30 ? -37.434 -42.494 -45.105 1.00 107.48 ? 41 TYR B N 1 ATOM 4599 C CA . TYR B 2 30 ? -36.826 -43.182 -46.238 1.00 100.45 ? 41 TYR B CA 1 ATOM 4600 C C . TYR B 2 30 ? -37.131 -44.671 -46.088 1.00 100.28 ? 41 TYR B C 1 ATOM 4601 O O . TYR B 2 30 ? -36.622 -45.326 -45.182 1.00 93.78 ? 41 TYR B O 1 ATOM 4602 C CB . TYR B 2 30 ? -35.321 -42.920 -46.325 1.00 100.99 ? 41 TYR B CB 1 ATOM 4603 C CG . TYR B 2 30 ? -34.945 -41.496 -46.694 1.00 102.74 ? 41 TYR B CG 1 ATOM 4604 C CD1 . TYR B 2 30 ? -34.794 -40.512 -45.724 1.00 108.44 ? 41 TYR B CD1 1 ATOM 4605 C CD2 . TYR B 2 30 ? -34.752 -41.135 -48.022 1.00 104.04 ? 41 TYR B CD2 1 ATOM 4606 C CE1 . TYR B 2 30 ? -34.444 -39.212 -46.071 1.00 103.00 ? 41 TYR B CE1 1 ATOM 4607 C CE2 . TYR B 2 30 ? -34.404 -39.843 -48.375 1.00 102.18 ? 41 TYR B CE2 1 ATOM 4608 C CZ . TYR B 2 30 ? -34.252 -38.886 -47.395 1.00 93.77 ? 41 TYR B CZ 1 ATOM 4609 O OH . TYR B 2 30 ? -33.907 -37.599 -47.742 1.00 88.66 ? 41 TYR B OH 1 ATOM 4610 N N . GLN B 2 31 ? -37.976 -45.199 -46.967 1.00 102.10 ? 42 GLN B N 1 ATOM 4611 C CA . GLN B 2 31 ? -38.206 -46.638 -47.019 1.00 101.53 ? 42 GLN B CA 1 ATOM 4612 C C . GLN B 2 31 ? -37.960 -47.267 -48.388 1.00 94.61 ? 42 GLN B C 1 ATOM 4613 O O . GLN B 2 31 ? -38.259 -46.671 -49.423 1.00 91.50 ? 42 GLN B O 1 ATOM 4614 C CB . GLN B 2 31 ? -39.654 -46.928 -46.614 1.00 105.62 ? 42 GLN B CB 1 ATOM 4615 C CG . GLN B 2 31 ? -40.522 -45.674 -46.547 1.00 108.23 ? 42 GLN B CG 1 ATOM 4616 C CD . GLN B 2 31 ? -41.941 -45.955 -46.092 1.00 110.17 ? 42 GLN B CD 1 ATOM 4617 O OE1 . GLN B 2 31 ? -42.191 -46.893 -45.337 1.00 112.86 ? 42 GLN B OE1 1 ATOM 4618 N NE2 . GLN B 2 31 ? -42.882 -45.138 -46.556 1.00 106.74 ? 42 GLN B NE2 1 ATOM 4619 N N . VAL B 2 32 ? -37.430 -48.489 -48.377 1.00 88.76 ? 43 VAL B N 1 ATOM 4620 C CA . VAL B 2 32 ? -36.726 -49.046 -49.529 1.00 85.89 ? 43 VAL B CA 1 ATOM 4621 C C . VAL B 2 32 ? -36.470 -50.548 -49.377 1.00 94.85 ? 43 VAL B C 1 ATOM 4622 O O . VAL B 2 32 ? -36.263 -51.048 -48.271 1.00 95.13 ? 43 VAL B O 1 ATOM 4623 C CB . VAL B 2 32 ? -35.394 -48.285 -49.776 1.00 75.84 ? 43 VAL B CB 1 ATOM 4624 C CG1 . VAL B 2 32 ? -34.181 -49.218 -49.764 1.00 75.57 ? 43 VAL B CG1 1 ATOM 4625 C CG2 . VAL B 2 32 ? -35.486 -47.483 -51.068 1.00 86.31 ? 43 VAL B CG2 1 ATOM 4626 N N . LEU B 2 33 ? -36.508 -51.249 -50.510 1.00 99.09 ? 44 LEU B N 1 ATOM 4627 C CA . LEU B 2 33 ? -36.462 -52.710 -50.563 1.00 92.17 ? 44 LEU B CA 1 ATOM 4628 C C . LEU B 2 33 ? -35.024 -53.226 -50.509 1.00 83.97 ? 44 LEU B C 1 ATOM 4629 O O . LEU B 2 33 ? -34.150 -52.677 -51.170 1.00 80.55 ? 44 LEU B O 1 ATOM 4630 C CB . LEU B 2 33 ? -37.163 -53.217 -51.829 1.00 89.30 ? 44 LEU B CB 1 ATOM 4631 C CG . LEU B 2 33 ? -38.692 -53.276 -51.751 1.00 87.28 ? 44 LEU B CG 1 ATOM 4632 C CD1 . LEU B 2 33 ? -39.313 -53.307 -53.142 1.00 86.38 ? 44 LEU B CD1 1 ATOM 4633 C CD2 . LEU B 2 33 ? -39.131 -54.479 -50.942 1.00 101.15 ? 44 LEU B CD2 1 ATOM 4634 N N . VAL B 2 34 ? -34.760 -54.226 -49.672 1.00 81.50 ? 45 VAL B N 1 ATOM 4635 C CA . VAL B 2 34 ? -33.397 -54.739 -49.530 1.00 87.21 ? 45 VAL B CA 1 ATOM 4636 C C . VAL B 2 34 ? -32.764 -55.062 -50.897 1.00 92.43 ? 45 VAL B C 1 ATOM 4637 O O . VAL B 2 34 ? -33.077 -56.071 -51.527 1.00 103.67 ? 45 VAL B O 1 ATOM 4638 C CB . VAL B 2 34 ? -33.359 -55.988 -48.597 1.00 90.39 ? 45 VAL B CB 1 ATOM 4639 C CG1 . VAL B 2 34 ? -34.384 -57.042 -49.012 1.00 91.75 ? 45 VAL B CG1 1 ATOM 4640 C CG2 . VAL B 2 34 ? -31.944 -56.565 -48.494 1.00 89.24 ? 45 VAL B CG2 1 ATOM 4641 N N . GLY B 2 35 ? -31.901 -54.169 -51.373 1.00 86.44 ? 46 GLY B N 1 ATOM 4642 C CA . GLY B 2 35 ? -31.121 -54.431 -52.570 1.00 84.84 ? 46 GLY B CA 1 ATOM 4643 C C . GLY B 2 35 ? -31.161 -53.322 -53.605 1.00 81.40 ? 46 GLY B C 1 ATOM 4644 O O . GLY B 2 35 ? -30.596 -53.468 -54.690 1.00 80.44 ? 46 GLY B O 1 ATOM 4645 N N . GLU B 2 36 ? -31.816 -52.210 -53.279 1.00 79.13 ? 47 GLU B N 1 ATOM 4646 C CA . GLU B 2 36 ? -31.796 -51.050 -54.166 1.00 78.58 ? 47 GLU B CA 1 ATOM 4647 C C . GLU B 2 36 ? -30.990 -49.895 -53.585 1.00 75.70 ? 47 GLU B C 1 ATOM 4648 O O . GLU B 2 36 ? -30.902 -49.739 -52.371 1.00 81.24 ? 47 GLU B O 1 ATOM 4649 C CB . GLU B 2 36 ? -33.218 -50.551 -54.475 1.00 81.33 ? 47 GLU B CB 1 ATOM 4650 C CG . GLU B 2 36 ? -34.226 -50.684 -53.355 1.00 82.21 ? 47 GLU B CG 1 ATOM 4651 C CD . GLU B 2 36 ? -35.554 -50.021 -53.683 1.00 86.67 ? 47 GLU B CD 1 ATOM 4652 O OE1 . GLU B 2 36 ? -36.614 -50.592 -53.359 1.00 88.56 ? 47 GLU B OE1 1 ATOM 4653 O OE2 . GLU B 2 36 ? -35.536 -48.908 -54.245 1.00 85.22 ? 47 GLU B OE2 1 ATOM 4654 N N . PRO B 2 37 ? -30.396 -49.079 -54.463 1.00 77.39 ? 48 PRO B N 1 ATOM 4655 C CA . PRO B 2 37 ? -29.619 -47.902 -54.070 1.00 90.26 ? 48 PRO B CA 1 ATOM 4656 C C . PRO B 2 37 ? -30.491 -46.861 -53.364 1.00 92.39 ? 48 PRO B C 1 ATOM 4657 O O . PRO B 2 37 ? -31.665 -46.722 -53.707 1.00 85.98 ? 48 PRO B O 1 ATOM 4658 C CB . PRO B 2 37 ? -29.083 -47.383 -55.406 1.00 99.88 ? 48 PRO B CB 1 ATOM 4659 C CG . PRO B 2 37 ? -30.066 -47.874 -56.405 1.00 96.52 ? 48 PRO B CG 1 ATOM 4660 C CD . PRO B 2 37 ? -30.400 -49.248 -55.925 1.00 88.51 ? 48 PRO B CD 1 ATOM 4661 N N . VAL B 2 38 ? -29.925 -46.146 -52.395 1.00 96.05 ? 49 VAL B N 1 ATOM 4662 C CA . VAL B 2 38 ? -30.645 -45.083 -51.694 1.00 89.39 ? 49 VAL B CA 1 ATOM 4663 C C . VAL B 2 38 ? -29.729 -43.928 -51.320 1.00 93.34 ? 49 VAL B C 1 ATOM 4664 O O . VAL B 2 38 ? -28.641 -44.135 -50.787 1.00 96.18 ? 49 VAL B O 1 ATOM 4665 C CB . VAL B 2 38 ? -31.333 -45.581 -50.392 1.00 91.34 ? 49 VAL B CB 1 ATOM 4666 C CG1 . VAL B 2 38 ? -32.829 -45.332 -50.456 1.00 88.69 ? 49 VAL B CG1 1 ATOM 4667 C CG2 . VAL B 2 38 ? -31.013 -47.051 -50.108 1.00 95.34 ? 49 VAL B CG2 1 ATOM 4668 N N . ARG B 2 39 ? -30.174 -42.709 -51.609 1.00 94.05 ? 50 ARG B N 1 ATOM 4669 C CA . ARG B 2 39 ? -29.405 -41.524 -51.257 1.00 107.16 ? 50 ARG B CA 1 ATOM 4670 C C . ARG B 2 39 ? -30.152 -40.730 -50.190 1.00 112.65 ? 50 ARG B C 1 ATOM 4671 O O . ARG B 2 39 ? -31.176 -40.103 -50.465 1.00 111.63 ? 50 ARG B O 1 ATOM 4672 C CB . ARG B 2 39 ? -29.143 -40.655 -52.494 1.00 108.35 ? 50 ARG B CB 1 ATOM 4673 C CG . ARG B 2 39 ? -28.079 -39.585 -52.289 1.00 106.37 ? 50 ARG B CG 1 ATOM 4674 C CD . ARG B 2 39 ? -28.664 -38.184 -52.224 1.00 111.40 ? 50 ARG B CD 1 ATOM 4675 N NE . ARG B 2 39 ? -28.535 -37.486 -53.501 1.00 115.04 ? 50 ARG B NE 1 ATOM 4676 C CZ . ARG B 2 39 ? -28.448 -36.166 -53.631 1.00 121.58 ? 50 ARG B CZ 1 ATOM 4677 N NH1 . ARG B 2 39 ? -28.460 -35.387 -52.559 1.00 115.46 ? 50 ARG B NH1 1 ATOM 4678 N NH2 . ARG B 2 39 ? -28.351 -35.625 -54.837 1.00 131.12 ? 50 ARG B NH2 1 ATOM 4679 N N . ILE B 2 40 ? -29.617 -40.768 -48.971 1.00 113.94 ? 51 ILE B N 1 ATOM 4680 C CA . ILE B 2 40 ? -30.171 -40.050 -47.823 1.00 102.37 ? 51 ILE B CA 1 ATOM 4681 C C . ILE B 2 40 ? -29.561 -38.661 -47.724 1.00 109.95 ? 51 ILE B C 1 ATOM 4682 O O . ILE B 2 40 ? -28.405 -38.518 -47.325 1.00 111.05 ? 51 ILE B O 1 ATOM 4683 C CB . ILE B 2 40 ? -29.902 -40.787 -46.485 1.00 98.04 ? 51 ILE B CB 1 ATOM 4684 C CG1 . ILE B 2 40 ? -30.438 -42.225 -46.492 1.00 93.14 ? 51 ILE B CG1 1 ATOM 4685 C CG2 . ILE B 2 40 ? -30.481 -39.997 -45.317 1.00 106.32 ? 51 ILE B CG2 1 ATOM 4686 C CD1 . ILE B 2 40 ? -31.705 -42.443 -47.272 1.00 91.75 ? 51 ILE B CD1 1 ATOM 4687 N N . LYS B 2 41 ? -30.330 -37.634 -48.071 1.00 112.24 ? 52 LYS B N 1 ATOM 4688 C CA . LYS B 2 41 ? -29.821 -36.282 -47.932 1.00 119.24 ? 52 LYS B CA 1 ATOM 4689 C C . LYS B 2 41 ? -29.914 -35.924 -46.461 1.00 117.19 ? 52 LYS B C 1 ATOM 4690 O O . LYS B 2 41 ? -30.681 -36.537 -45.723 1.00 116.47 ? 52 LYS B O 1 ATOM 4691 C CB . LYS B 2 41 ? -30.638 -35.308 -48.786 1.00 118.65 ? 52 LYS B CB 1 ATOM 4692 C CG . LYS B 2 41 ? -30.596 -35.632 -50.266 1.00 118.06 ? 52 LYS B CG 1 ATOM 4693 C CD . LYS B 2 41 ? -31.997 -35.701 -50.868 1.00 120.09 ? 52 LYS B CD 1 ATOM 4694 C CE . LYS B 2 41 ? -32.606 -34.327 -51.083 1.00 119.30 ? 52 LYS B CE 1 ATOM 4695 N NZ . LYS B 2 41 ? -31.654 -33.420 -51.777 1.00 125.99 ? 52 LYS B NZ 1 ATOM 4696 N N . CYS B 2 42 ? -29.140 -34.938 -46.028 1.00 114.76 ? 53 CYS B N 1 ATOM 4697 C CA . CYS B 2 42 ? -29.266 -34.452 -44.666 1.00 111.68 ? 53 CYS B CA 1 ATOM 4698 C C . CYS B 2 42 ? -30.427 -33.467 -44.671 1.00 114.55 ? 53 CYS B C 1 ATOM 4699 O O . CYS B 2 42 ? -30.427 -32.515 -45.451 1.00 123.74 ? 53 CYS B O 1 ATOM 4700 C CB . CYS B 2 42 ? -27.972 -33.815 -44.157 1.00 111.27 ? 53 CYS B CB 1 ATOM 4701 S SG . CYS B 2 42 ? -28.152 -32.987 -42.559 1.00 90.19 ? 53 CYS B SG 1 ATOM 4702 N N . ALA B 2 43 ? -31.414 -33.696 -43.814 1.00 108.54 ? 54 ALA B N 1 ATOM 4703 C CA . ALA B 2 43 ? -32.660 -32.931 -43.846 1.00 110.91 ? 54 ALA B CA 1 ATOM 4704 C C . ALA B 2 43 ? -32.429 -31.459 -43.506 1.00 117.96 ? 54 ALA B C 1 ATOM 4705 O O . ALA B 2 43 ? -33.127 -30.581 -44.019 1.00 118.51 ? 54 ALA B O 1 ATOM 4706 C CB . ALA B 2 43 ? -33.681 -33.543 -42.897 1.00 108.99 ? 54 ALA B CB 1 ATOM 4707 N N . LEU B 2 44 ? -31.459 -31.203 -42.633 1.00 117.43 ? 55 LEU B N 1 ATOM 4708 C CA . LEU B 2 44 ? -31.225 -29.873 -42.066 1.00 118.01 ? 55 LEU B CA 1 ATOM 4709 C C . LEU B 2 44 ? -30.993 -28.773 -43.098 1.00 121.47 ? 55 LEU B C 1 ATOM 4710 O O . LEU B 2 44 ? -31.266 -27.602 -42.829 1.00 127.05 ? 55 LEU B O 1 ATOM 4711 C CB . LEU B 2 44 ? -30.033 -29.909 -41.107 1.00 112.98 ? 55 LEU B CB 1 ATOM 4712 C CG . LEU B 2 44 ? -30.083 -30.928 -39.974 1.00 108.01 ? 55 LEU B CG 1 ATOM 4713 C CD1 . LEU B 2 44 ? -28.741 -31.045 -39.271 1.00 110.04 ? 55 LEU B CD1 1 ATOM 4714 C CD2 . LEU B 2 44 ? -31.134 -30.445 -39.002 1.00 102.19 ? 55 LEU B CD2 1 ATOM 4715 N N . PHE B 2 45 ? -30.489 -29.135 -44.271 1.00 115.47 ? 56 PHE B N 1 ATOM 4716 C CA . PHE B 2 45 ? -30.154 -28.131 -45.268 1.00 113.90 ? 56 PHE B CA 1 ATOM 4717 C C . PHE B 2 45 ? -31.424 -27.782 -46.033 1.00 112.30 ? 56 PHE B C 1 ATOM 4718 O O . PHE B 2 45 ? -31.611 -26.657 -46.497 1.00 116.66 ? 56 PHE B O 1 ATOM 4719 C CB . PHE B 2 45 ? -29.086 -28.657 -46.232 1.00 120.34 ? 56 PHE B CB 1 ATOM 4720 C CG . PHE B 2 45 ? -27.747 -28.905 -45.591 1.00 123.86 ? 56 PHE B CG 1 ATOM 4721 C CD1 . PHE B 2 45 ? -26.896 -27.857 -45.288 1.00 130.87 ? 56 PHE B CD1 1 ATOM 4722 C CD2 . PHE B 2 45 ? -27.335 -30.198 -45.308 1.00 119.50 ? 56 PHE B CD2 1 ATOM 4723 C CE1 . PHE B 2 45 ? -25.664 -28.094 -44.703 1.00 130.33 ? 56 PHE B CE1 1 ATOM 4724 C CE2 . PHE B 2 45 ? -26.104 -30.442 -44.725 1.00 121.68 ? 56 PHE B CE2 1 ATOM 4725 C CZ . PHE B 2 45 ? -25.267 -29.387 -44.422 1.00 125.88 ? 56 PHE B CZ 1 ATOM 4726 N N . TYR B 2 46 ? -32.291 -28.781 -46.150 1.00 111.01 ? 57 TYR B N 1 ATOM 4727 C CA . TYR B 2 46 ? -33.464 -28.722 -47.009 1.00 116.84 ? 57 TYR B CA 1 ATOM 4728 C C . TYR B 2 46 ? -34.741 -28.446 -46.213 1.00 105.15 ? 57 TYR B C 1 ATOM 4729 O O . TYR B 2 46 ? -35.705 -29.209 -46.288 1.00 103.47 ? 57 TYR B O 1 ATOM 4730 C CB . TYR B 2 46 ? -33.564 -30.031 -47.789 1.00 128.05 ? 57 TYR B CB 1 ATOM 4731 C CG . TYR B 2 46 ? -32.298 -30.310 -48.574 1.00 122.73 ? 57 TYR B CG 1 ATOM 4732 C CD1 . TYR B 2 46 ? -31.572 -29.270 -49.144 1.00 123.96 ? 57 TYR B CD1 1 ATOM 4733 C CD2 . TYR B 2 46 ? -31.792 -31.599 -48.688 1.00 118.83 ? 57 TYR B CD2 1 ATOM 4734 C CE1 . TYR B 2 46 ? -30.402 -29.507 -49.839 1.00 124.84 ? 57 TYR B CE1 1 ATOM 4735 C CE2 . TYR B 2 46 ? -30.618 -31.845 -49.378 1.00 121.89 ? 57 TYR B CE2 1 ATOM 4736 C CZ . TYR B 2 46 ? -29.930 -30.797 -49.954 1.00 126.05 ? 57 TYR B CZ 1 ATOM 4737 O OH . TYR B 2 46 ? -28.765 -31.038 -50.646 1.00 127.61 ? 57 TYR B OH 1 ATOM 4738 N N . GLY B 2 47 ? -34.740 -27.366 -45.438 1.00 100.50 ? 58 GLY B N 1 ATOM 4739 C CA . GLY B 2 47 ? -35.873 -27.056 -44.584 1.00 110.54 ? 58 GLY B CA 1 ATOM 4740 C C . GLY B 2 47 ? -35.492 -26.253 -43.355 1.00 120.28 ? 58 GLY B C 1 ATOM 4741 O O . GLY B 2 47 ? -35.774 -25.055 -43.273 1.00 122.98 ? 58 GLY B O 1 ATOM 4742 N N . TYR B 2 48 ? -34.858 -26.923 -42.396 1.00 119.23 ? 59 TYR B N 1 ATOM 4743 C CA . TYR B 2 48 ? -34.583 -26.350 -41.080 1.00 119.08 ? 59 TYR B CA 1 ATOM 4744 C C . TYR B 2 48 ? -33.682 -25.119 -41.142 1.00 128.78 ? 59 TYR B C 1 ATOM 4745 O O . TYR B 2 48 ? -34.134 -23.994 -40.918 1.00 128.91 ? 59 TYR B O 1 ATOM 4746 C CB . TYR B 2 48 ? -33.921 -27.384 -40.158 1.00 111.81 ? 59 TYR B CB 1 ATOM 4747 C CG . TYR B 2 48 ? -34.652 -28.697 -39.987 1.00 107.40 ? 59 TYR B CG 1 ATOM 4748 C CD1 . TYR B 2 48 ? -34.637 -29.661 -40.986 1.00 112.21 ? 59 TYR B CD1 1 ATOM 4749 C CD2 . TYR B 2 48 ? -35.337 -28.981 -38.812 1.00 107.53 ? 59 TYR B CD2 1 ATOM 4750 C CE1 . TYR B 2 48 ? -35.298 -30.868 -40.825 1.00 112.44 ? 59 TYR B CE1 1 ATOM 4751 C CE2 . TYR B 2 48 ? -35.997 -30.183 -38.642 1.00 108.23 ? 59 TYR B CE2 1 ATOM 4752 C CZ . TYR B 2 48 ? -35.975 -31.122 -39.650 1.00 104.25 ? 59 TYR B CZ 1 ATOM 4753 O OH . TYR B 2 48 ? -36.635 -32.318 -39.480 1.00 97.53 ? 59 TYR B OH 1 ATOM 4754 N N . ILE B 2 49 ? -32.406 -25.346 -41.450 1.00 131.71 ? 60 ILE B N 1 ATOM 4755 C CA . ILE B 2 49 ? -31.417 -24.274 -41.480 1.00 129.30 ? 60 ILE B CA 1 ATOM 4756 C C . ILE B 2 49 ? -31.421 -23.516 -42.815 1.00 134.50 ? 60 ILE B C 1 ATOM 4757 O O . ILE B 2 49 ? -31.908 -24.010 -43.830 1.00 140.12 ? 60 ILE B O 1 ATOM 4758 C CB . ILE B 2 49 ? -30.011 -24.847 -41.189 1.00 128.89 ? 60 ILE B CB 1 ATOM 4759 C CG1 . ILE B 2 49 ? -30.115 -25.978 -40.161 1.00 127.15 ? 60 ILE B CG1 1 ATOM 4760 C CG2 . ILE B 2 49 ? -29.066 -23.763 -40.690 1.00 138.64 ? 60 ILE B CG2 1 ATOM 4761 C CD1 . ILE B 2 49 ? -28.817 -26.727 -39.919 1.00 130.62 ? 60 ILE B CD1 1 ATOM 4762 N N . ARG B 2 50 ? -30.869 -22.306 -42.786 1.00 135.63 ? 61 ARG B N 1 ATOM 4763 C CA . ARG B 2 50 ? -30.912 -21.379 -43.913 1.00 141.87 ? 61 ARG B CA 1 ATOM 4764 C C . ARG B 2 50 ? -29.974 -21.657 -45.106 1.00 138.04 ? 61 ARG B C 1 ATOM 4765 O O . ARG B 2 50 ? -30.338 -21.379 -46.251 1.00 136.60 ? 61 ARG B O 1 ATOM 4766 C CB . ARG B 2 50 ? -30.649 -19.970 -43.381 1.00 152.46 ? 61 ARG B CB 1 ATOM 4767 C CG . ARG B 2 50 ? -31.753 -18.998 -43.736 1.00 152.16 ? 61 ARG B CG 1 ATOM 4768 C CD . ARG B 2 50 ? -31.701 -18.452 -45.143 1.00 153.14 ? 61 ARG B CD 1 ATOM 4769 N NE . ARG B 2 50 ? -33.061 -18.275 -45.650 1.00 161.32 ? 61 ARG B NE 1 ATOM 4770 C CZ . ARG B 2 50 ? -33.925 -17.360 -45.216 1.00 160.67 ? 61 ARG B CZ 1 ATOM 4771 N NH1 . ARG B 2 50 ? -33.588 -16.517 -44.249 1.00 151.55 ? 61 ARG B NH1 1 ATOM 4772 N NH2 . ARG B 2 50 ? -35.135 -17.289 -45.756 1.00 163.40 ? 61 ARG B NH2 1 ATOM 4773 N N . THR B 2 51 ? -28.780 -22.197 -44.853 1.00 136.86 ? 62 THR B N 1 ATOM 4774 C CA . THR B 2 51 ? -27.757 -22.307 -45.907 1.00 138.03 ? 62 THR B CA 1 ATOM 4775 C C . THR B 2 51 ? -27.680 -23.679 -46.586 1.00 137.89 ? 62 THR B C 1 ATOM 4776 O O . THR B 2 51 ? -28.391 -24.609 -46.206 1.00 139.67 ? 62 THR B O 1 ATOM 4777 C CB . THR B 2 51 ? -26.343 -21.975 -45.355 1.00 132.52 ? 62 THR B CB 1 ATOM 4778 O OG1 . THR B 2 51 ? -25.998 -22.890 -44.306 1.00 124.56 ? 62 THR B OG1 1 ATOM 4779 C CG2 . THR B 2 51 ? -26.284 -20.547 -44.823 1.00 132.52 ? 62 THR B CG2 1 ATOM 4780 N N . ASN B 2 52 ? -26.817 -23.795 -47.598 1.00 137.35 ? 63 ASN B N 1 ATOM 4781 C CA . ASN B 2 52 ? -26.493 -25.099 -48.178 1.00 140.01 ? 63 ASN B CA 1 ATOM 4782 C C . ASN B 2 52 ? -25.186 -25.665 -47.617 1.00 135.86 ? 63 ASN B C 1 ATOM 4783 O O . ASN B 2 52 ? -24.593 -25.092 -46.702 1.00 131.21 ? 63 ASN B O 1 ATOM 4784 C CB . ASN B 2 52 ? -26.428 -25.024 -49.715 1.00 144.83 ? 63 ASN B CB 1 ATOM 4785 C CG . ASN B 2 52 ? -25.656 -23.819 -50.225 1.00 137.77 ? 63 ASN B CG 1 ATOM 4786 O OD1 . ASN B 2 52 ? -24.566 -23.520 -49.745 1.00 135.82 ? 63 ASN B OD1 1 ATOM 4787 N ND2 . ASN B 2 52 ? -26.217 -23.129 -51.213 1.00 127.33 ? 63 ASN B ND2 1 ATOM 4788 N N . TYR B 2 53 ? -24.746 -26.791 -48.174 1.00 133.83 ? 64 TYR B N 1 ATOM 4789 C CA . TYR B 2 53 ? -23.599 -27.536 -47.647 1.00 133.17 ? 64 TYR B CA 1 ATOM 4790 C C . TYR B 2 53 ? -22.248 -26.841 -47.850 1.00 138.08 ? 64 TYR B C 1 ATOM 4791 O O . TYR B 2 53 ? -21.454 -26.739 -46.913 1.00 137.36 ? 64 TYR B O 1 ATOM 4792 C CB . TYR B 2 53 ? -23.560 -28.942 -48.254 1.00 133.33 ? 64 TYR B CB 1 ATOM 4793 C CG . TYR B 2 53 ? -22.259 -29.679 -48.017 1.00 135.86 ? 64 TYR B CG 1 ATOM 4794 C CD1 . TYR B 2 53 ? -22.076 -30.427 -46.863 1.00 128.58 ? 64 TYR B CD1 1 ATOM 4795 C CD2 . TYR B 2 53 ? -21.238 -29.671 -48.961 1.00 137.71 ? 64 TYR B CD2 1 ATOM 4796 C CE1 . TYR B 2 53 ? -20.905 -31.112 -46.632 1.00 126.63 ? 64 TYR B CE1 1 ATOM 4797 C CE2 . TYR B 2 53 ? -20.057 -30.359 -48.739 1.00 138.04 ? 64 TYR B CE2 1 ATOM 4798 C CZ . TYR B 2 53 ? -19.900 -31.082 -47.573 1.00 136.95 ? 64 TYR B CZ 1 ATOM 4799 O OH . TYR B 2 53 ? -18.734 -31.769 -47.333 1.00 148.28 ? 64 TYR B OH 1 ATOM 4800 N N . SER B 2 54 ? -21.982 -26.399 -49.078 1.00 141.35 ? 65 SER B N 1 ATOM 4801 C CA . SER B 2 54 ? -20.717 -25.746 -49.428 1.00 140.36 ? 65 SER B CA 1 ATOM 4802 C C . SER B 2 54 ? -20.410 -24.559 -48.512 1.00 147.03 ? 65 SER B C 1 ATOM 4803 O O . SER B 2 54 ? -19.263 -24.351 -48.112 1.00 149.16 ? 65 SER B O 1 ATOM 4804 C CB . SER B 2 54 ? -20.736 -25.294 -50.892 1.00 123.79 ? 65 SER B CB 1 ATOM 4805 O OG . SER B 2 54 ? -21.620 -24.206 -51.090 1.00 125.22 ? 65 SER B OG 1 ATOM 4806 N N . LEU B 2 55 ? -21.441 -23.778 -48.205 1.00 146.78 ? 66 LEU B N 1 ATOM 4807 C CA . LEU B 2 55 ? -21.319 -22.587 -47.364 1.00 141.19 ? 66 LEU B CA 1 ATOM 4808 C C . LEU B 2 55 ? -21.011 -22.957 -45.909 1.00 140.40 ? 66 LEU B C 1 ATOM 4809 O O . LEU B 2 55 ? -20.243 -22.273 -45.229 1.00 138.99 ? 66 LEU B O 1 ATOM 4810 C CB . LEU B 2 55 ? -22.596 -21.748 -47.445 1.00 138.30 ? 66 LEU B CB 1 ATOM 4811 C CG . LEU B 2 55 ? -22.887 -21.117 -48.810 1.00 137.72 ? 66 LEU B CG 1 ATOM 4812 C CD1 . LEU B 2 55 ? -24.002 -20.085 -48.715 1.00 131.78 ? 66 LEU B CD1 1 ATOM 4813 C CD2 . LEU B 2 55 ? -21.633 -20.506 -49.415 1.00 146.90 ? 66 LEU B CD2 1 ATOM 4814 N N . ALA B 2 56 ? -21.639 -24.030 -45.439 1.00 138.60 ? 67 ALA B N 1 ATOM 4815 C CA . ALA B 2 56 ? -21.392 -24.579 -44.106 1.00 133.25 ? 67 ALA B CA 1 ATOM 4816 C C . ALA B 2 56 ? -19.913 -24.924 -43.930 1.00 134.25 ? 67 ALA B C 1 ATOM 4817 O O . ALA B 2 56 ? -19.339 -24.710 -42.863 1.00 135.96 ? 67 ALA B O 1 ATOM 4818 C CB . ALA B 2 56 ? -22.258 -25.801 -43.861 1.00 137.51 ? 67 ALA B CB 1 ATOM 4819 N N . GLN B 2 57 ? -19.309 -25.471 -44.981 1.00 131.83 ? 68 GLN B N 1 ATOM 4820 C CA . GLN B 2 57 ? -17.894 -25.839 -44.977 1.00 127.14 ? 68 GLN B CA 1 ATOM 4821 C C . GLN B 2 57 ? -16.987 -24.610 -44.911 1.00 127.95 ? 68 GLN B C 1 ATOM 4822 O O . GLN B 2 57 ? -16.108 -24.516 -44.055 1.00 125.96 ? 68 GLN B O 1 ATOM 4823 C CB . GLN B 2 57 ? -17.550 -26.637 -46.236 1.00 127.33 ? 68 GLN B CB 1 ATOM 4824 C CG . GLN B 2 57 ? -17.378 -28.121 -46.033 1.00 140.07 ? 68 GLN B CG 1 ATOM 4825 C CD . GLN B 2 57 ? -16.498 -28.748 -47.099 1.00 156.26 ? 68 GLN B CD 1 ATOM 4826 O OE1 . GLN B 2 57 ? -16.407 -29.970 -47.210 1.00 166.72 ? 68 GLN B OE1 1 ATOM 4827 N NE2 . GLN B 2 57 ? -15.826 -27.907 -47.879 1.00 148.04 ? 68 GLN B NE2 1 ATOM 4828 N N . SER B 2 58 ? -17.191 -23.701 -45.861 1.00 129.85 ? 69 SER B N 1 ATOM 4829 C CA . SER B 2 58 ? -16.576 -22.370 -45.880 1.00 127.85 ? 69 SER B CA 1 ATOM 4830 C C . SER B 2 58 ? -16.532 -21.652 -44.524 1.00 126.05 ? 69 SER B C 1 ATOM 4831 O O . SER B 2 58 ? -15.508 -21.075 -44.156 1.00 127.89 ? 69 SER B O 1 ATOM 4832 C CB . SER B 2 58 ? -17.302 -21.484 -46.896 1.00 127.72 ? 69 SER B CB 1 ATOM 4833 O OG . SER B 2 58 ? -17.311 -22.084 -48.180 1.00 128.81 ? 69 SER B OG 1 ATOM 4834 N N . ALA B 2 59 ? -17.640 -21.685 -43.790 1.00 130.37 ? 70 ALA B N 1 ATOM 4835 C CA . ALA B 2 59 ? -17.718 -21.064 -42.465 1.00 133.52 ? 70 ALA B CA 1 ATOM 4836 C C . ALA B 2 59 ? -17.080 -21.926 -41.372 1.00 137.51 ? 70 ALA B C 1 ATOM 4837 O O . ALA B 2 59 ? -17.200 -21.631 -40.182 1.00 129.08 ? 70 ALA B O 1 ATOM 4838 C CB . ALA B 2 59 ? -19.161 -20.763 -42.117 1.00 133.69 ? 70 ALA B CB 1 ATOM 4839 N N . GLY B 2 60 ? -16.413 -22.996 -41.793 1.00 146.10 ? 71 GLY B N 1 ATOM 4840 C CA . GLY B 2 60 ? -15.545 -23.768 -40.923 1.00 144.15 ? 71 GLY B CA 1 ATOM 4841 C C . GLY B 2 60 ? -16.320 -24.695 -40.011 1.00 134.87 ? 71 GLY B C 1 ATOM 4842 O O . GLY B 2 60 ? -15.908 -24.979 -38.886 1.00 123.61 ? 71 GLY B O 1 ATOM 4843 N N . LEU B 2 61 ? -17.454 -25.172 -40.511 1.00 134.48 ? 72 LEU B N 1 ATOM 4844 C CA . LEU B 2 61 ? -18.294 -26.103 -39.768 1.00 124.72 ? 72 LEU B CA 1 ATOM 4845 C C . LEU B 2 61 ? -18.057 -27.534 -40.227 1.00 124.01 ? 72 LEU B C 1 ATOM 4846 O O . LEU B 2 61 ? -17.828 -27.797 -41.408 1.00 127.49 ? 72 LEU B O 1 ATOM 4847 C CB . LEU B 2 61 ? -19.780 -25.749 -39.887 1.00 120.09 ? 72 LEU B CB 1 ATOM 4848 C CG . LEU B 2 61 ? -20.278 -24.365 -39.465 1.00 125.92 ? 72 LEU B CG 1 ATOM 4849 C CD1 . LEU B 2 61 ? -21.651 -24.503 -38.830 1.00 131.89 ? 72 LEU B CD1 1 ATOM 4850 C CD2 . LEU B 2 61 ? -19.327 -23.689 -38.489 1.00 135.89 ? 72 LEU B CD2 1 ATOM 4851 N N . SER B 2 62 ? -18.118 -28.454 -39.274 1.00 123.53 ? 73 SER B N 1 ATOM 4852 C CA . SER B 2 62 ? -17.954 -29.872 -39.546 1.00 127.82 ? 73 SER B CA 1 ATOM 4853 C C . SER B 2 62 ? -19.322 -30.506 -39.768 1.00 134.77 ? 73 SER B C 1 ATOM 4854 O O . SER B 2 62 ? -20.319 -30.069 -39.197 1.00 134.79 ? 73 SER B O 1 ATOM 4855 C CB . SER B 2 62 ? -17.212 -30.563 -38.398 1.00 129.75 ? 73 SER B CB 1 ATOM 4856 O OG . SER B 2 62 ? -18.107 -31.011 -37.396 1.00 132.10 ? 73 SER B OG 1 ATOM 4857 N N . LEU B 2 63 ? -19.359 -31.534 -40.608 1.00 135.58 ? 74 LEU B N 1 ATOM 4858 C CA . LEU B 2 63 ? -20.571 -32.311 -40.849 1.00 123.25 ? 74 LEU B CA 1 ATOM 4859 C C . LEU B 2 63 ? -20.260 -33.734 -40.432 1.00 122.58 ? 74 LEU B C 1 ATOM 4860 O O . LEU B 2 63 ? -19.314 -34.347 -40.931 1.00 123.12 ? 74 LEU B O 1 ATOM 4861 C CB . LEU B 2 63 ? -21.014 -32.246 -42.318 1.00 112.20 ? 74 LEU B CB 1 ATOM 4862 C CG . LEU B 2 63 ? -22.462 -32.654 -42.648 1.00 104.72 ? 74 LEU B CG 1 ATOM 4863 C CD1 . LEU B 2 63 ? -22.875 -32.177 -44.023 1.00 112.34 ? 74 LEU B CD1 1 ATOM 4864 C CD2 . LEU B 2 63 ? -22.671 -34.151 -42.557 1.00 107.52 ? 74 LEU B CD2 1 ATOM 4865 N N . MET B 2 64 ? -21.066 -34.267 -39.520 1.00 117.15 ? 75 MET B N 1 ATOM 4866 C CA . MET B 2 64 ? -20.811 -35.609 -39.046 1.00 113.44 ? 75 MET B CA 1 ATOM 4867 C C . MET B 2 64 ? -22.059 -36.476 -39.045 1.00 116.96 ? 75 MET B C 1 ATOM 4868 O O . MET B 2 64 ? -23.167 -35.991 -38.816 1.00 116.76 ? 75 MET B O 1 ATOM 4869 C CB . MET B 2 64 ? -20.296 -35.494 -37.612 1.00 116.03 ? 75 MET B CB 1 ATOM 4870 C CG . MET B 2 64 ? -18.894 -34.947 -37.471 1.00 132.94 ? 75 MET B CG 1 ATOM 4871 S SD . MET B 2 64 ? -17.704 -36.255 -37.257 1.00 168.76 ? 75 MET B SD 1 ATOM 4872 C CE . MET B 2 64 ? -18.545 -37.203 -35.999 1.00 135.69 ? 75 MET B CE 1 ATOM 4873 N N . TRP B 2 65 ? -21.869 -37.765 -39.312 1.00 116.85 ? 76 TRP B N 1 ATOM 4874 C CA . TRP B 2 65 ? -22.959 -38.732 -39.264 1.00 112.49 ? 76 TRP B CA 1 ATOM 4875 C C . TRP B 2 65 ? -22.847 -39.746 -38.115 1.00 117.31 ? 76 TRP B C 1 ATOM 4876 O O . TRP B 2 65 ? -21.747 -40.194 -37.788 1.00 126.94 ? 76 TRP B O 1 ATOM 4877 C CB . TRP B 2 65 ? -23.072 -39.475 -40.601 1.00 109.33 ? 76 TRP B CB 1 ATOM 4878 C CG . TRP B 2 65 ? -23.549 -38.586 -41.730 1.00 114.76 ? 76 TRP B CG 1 ATOM 4879 C CD1 . TRP B 2 65 ? -22.768 -37.813 -42.545 1.00 125.82 ? 76 TRP B CD1 1 ATOM 4880 C CD2 . TRP B 2 65 ? -24.907 -38.315 -42.106 1.00 106.20 ? 76 TRP B CD2 1 ATOM 4881 N NE1 . TRP B 2 65 ? -23.551 -37.118 -43.431 1.00 123.11 ? 76 TRP B NE1 1 ATOM 4882 C CE2 . TRP B 2 65 ? -24.867 -37.401 -43.181 1.00 106.44 ? 76 TRP B CE2 1 ATOM 4883 C CE3 . TRP B 2 65 ? -26.150 -38.771 -41.653 1.00 102.99 ? 76 TRP B CE3 1 ATOM 4884 C CZ2 . TRP B 2 65 ? -26.019 -36.935 -43.808 1.00 98.32 ? 76 TRP B CZ2 1 ATOM 4885 C CZ3 . TRP B 2 65 ? -27.293 -38.306 -42.278 1.00 101.63 ? 76 TRP B CZ3 1 ATOM 4886 C CH2 . TRP B 2 65 ? -27.219 -37.396 -43.344 1.00 99.15 ? 76 TRP B CH2 1 ATOM 4887 N N . TYR B 2 66 ? -23.967 -40.071 -37.478 1.00 109.11 ? 77 TYR B N 1 ATOM 4888 C CA . TYR B 2 66 ? -24.007 -41.147 -36.484 1.00 106.09 ? 77 TYR B CA 1 ATOM 4889 C C . TYR B 2 66 ? -25.202 -42.052 -36.764 1.00 101.24 ? 77 TYR B C 1 ATOM 4890 O O . TYR B 2 66 ? -26.182 -41.622 -37.369 1.00 99.78 ? 77 TYR B O 1 ATOM 4891 C CB . TYR B 2 66 ? -24.074 -40.643 -35.039 1.00 109.04 ? 77 TYR B CB 1 ATOM 4892 C CG . TYR B 2 66 ? -22.957 -39.735 -34.577 1.00 114.02 ? 77 TYR B CG 1 ATOM 4893 C CD1 . TYR B 2 66 ? -22.904 -38.395 -34.937 1.00 120.80 ? 77 TYR B CD1 1 ATOM 4894 C CD2 . TYR B 2 66 ? -21.960 -40.230 -33.746 1.00 119.01 ? 77 TYR B CD2 1 ATOM 4895 C CE1 . TYR B 2 66 ? -21.872 -37.578 -34.489 1.00 130.96 ? 77 TYR B CE1 1 ATOM 4896 C CE2 . TYR B 2 66 ? -20.933 -39.429 -33.296 1.00 131.49 ? 77 TYR B CE2 1 ATOM 4897 C CZ . TYR B 2 66 ? -20.890 -38.104 -33.668 1.00 136.72 ? 77 TYR B CZ 1 ATOM 4898 O OH . TYR B 2 66 ? -19.868 -37.303 -33.210 1.00 144.20 ? 77 TYR B OH 1 ATOM 4899 N N . LYS B 2 67 ? -25.116 -43.307 -36.334 1.00 100.86 ? 78 LYS B N 1 ATOM 4900 C CA . LYS B 2 67 ? -26.204 -44.247 -36.569 1.00 95.31 ? 78 LYS B CA 1 ATOM 4901 C C . LYS B 2 67 ? -26.713 -44.903 -35.299 1.00 100.66 ? 78 LYS B C 1 ATOM 4902 O O . LYS B 2 67 ? -25.978 -45.617 -34.620 1.00 109.07 ? 78 LYS B O 1 ATOM 4903 C CB . LYS B 2 67 ? -25.782 -45.347 -37.542 1.00 97.03 ? 78 LYS B CB 1 ATOM 4904 C CG . LYS B 2 67 ? -26.918 -46.316 -37.823 1.00 95.18 ? 78 LYS B CG 1 ATOM 4905 C CD . LYS B 2 67 ? -26.466 -47.560 -38.558 1.00 100.52 ? 78 LYS B CD 1 ATOM 4906 C CE . LYS B 2 67 ? -27.587 -48.590 -38.598 1.00 96.61 ? 78 LYS B CE 1 ATOM 4907 N NZ . LYS B 2 67 ? -27.174 -49.854 -39.267 1.00 93.94 ? 78 LYS B NZ 1 ATOM 4908 N N . SER B 2 68 ? -27.979 -44.661 -34.990 1.00 98.14 ? 79 SER B N 1 ATOM 4909 C CA . SER B 2 68 ? -28.637 -45.341 -33.892 1.00 99.20 ? 79 SER B CA 1 ATOM 4910 C C . SER B 2 68 ? -29.487 -46.431 -34.531 1.00 92.20 ? 79 SER B C 1 ATOM 4911 O O . SER B 2 68 ? -29.839 -46.328 -35.707 1.00 89.64 ? 79 SER B O 1 ATOM 4912 C CB . SER B 2 68 ? -29.477 -44.369 -33.062 1.00 103.11 ? 79 SER B CB 1 ATOM 4913 O OG . SER B 2 68 ? -30.140 -45.037 -32.005 1.00 116.51 ? 79 SER B OG 1 ATOM 4914 N N . SER B 2 69 ? -29.816 -47.473 -33.779 1.00 91.96 ? 80 SER B N 1 ATOM 4915 C CA . SER B 2 69 ? -30.561 -48.588 -34.347 1.00 83.03 ? 80 SER B CA 1 ATOM 4916 C C . SER B 2 69 ? -32.038 -48.406 -34.029 1.00 87.52 ? 80 SER B C 1 ATOM 4917 O O . SER B 2 69 ? -32.844 -49.312 -34.222 1.00 85.02 ? 80 SER B O 1 ATOM 4918 C CB . SER B 2 69 ? -30.055 -49.922 -33.799 1.00 74.37 ? 80 SER B CB 1 ATOM 4919 O OG . SER B 2 69 ? -28.715 -49.813 -33.361 1.00 76.73 ? 80 SER B OG 1 ATOM 4920 N N . GLY B 2 70 ? -32.379 -47.219 -33.540 1.00 98.98 ? 81 GLY B N 1 ATOM 4921 C CA . GLY B 2 70 ? -33.722 -46.935 -33.075 1.00 108.65 ? 81 GLY B CA 1 ATOM 4922 C C . GLY B 2 70 ? -33.629 -46.133 -31.791 1.00 118.84 ? 81 GLY B C 1 ATOM 4923 O O . GLY B 2 70 ? -32.529 -45.844 -31.323 1.00 130.12 ? 81 GLY B O 1 ATOM 4924 N N . PRO B 2 71 ? -34.780 -45.740 -31.227 1.00 109.71 ? 82 PRO B N 1 ATOM 4925 C CA . PRO B 2 71 ? -34.760 -45.068 -29.927 1.00 102.32 ? 82 PRO B CA 1 ATOM 4926 C C . PRO B 2 71 ? -35.125 -46.032 -28.794 1.00 110.82 ? 82 PRO B C 1 ATOM 4927 O O . PRO B 2 71 ? -36.165 -46.690 -28.844 1.00 117.30 ? 82 PRO B O 1 ATOM 4928 C CB . PRO B 2 71 ? -35.815 -43.963 -30.087 1.00 94.96 ? 82 PRO B CB 1 ATOM 4929 C CG . PRO B 2 71 ? -36.572 -44.288 -31.384 1.00 100.17 ? 82 PRO B CG 1 ATOM 4930 C CD . PRO B 2 71 ? -36.105 -45.638 -31.855 1.00 110.13 ? 82 PRO B CD 1 ATOM 4931 N N . GLY B 2 72 ? -34.261 -46.117 -27.786 1.00 118.01 ? 83 GLY B N 1 ATOM 4932 C CA . GLY B 2 72 ? -33.021 -45.363 -27.782 1.00 117.34 ? 83 GLY B CA 1 ATOM 4933 C C . GLY B 2 72 ? -31.741 -46.174 -27.691 1.00 119.19 ? 83 GLY B C 1 ATOM 4934 O O . GLY B 2 72 ? -31.359 -46.631 -26.615 1.00 119.92 ? 83 GLY B O 1 ATOM 4935 N N . ASP B 2 73 ? -31.073 -46.349 -28.825 1.00 125.49 ? 84 ASP B N 1 ATOM 4936 C CA . ASP B 2 73 ? -29.779 -47.016 -28.848 1.00 127.29 ? 84 ASP B CA 1 ATOM 4937 C C . ASP B 2 73 ? -28.769 -45.909 -29.071 1.00 129.45 ? 84 ASP B C 1 ATOM 4938 O O . ASP B 2 73 ? -29.050 -44.940 -29.778 1.00 124.42 ? 84 ASP B O 1 ATOM 4939 C CB . ASP B 2 73 ? -29.682 -48.099 -29.931 1.00 120.25 ? 84 ASP B CB 1 ATOM 4940 C CG . ASP B 2 73 ? -30.937 -48.949 -30.032 1.00 124.76 ? 84 ASP B CG 1 ATOM 4941 O OD1 . ASP B 2 73 ? -32.036 -48.446 -29.719 1.00 125.64 ? 84 ASP B OD1 1 ATOM 4942 O OD2 . ASP B 2 73 ? -30.817 -50.133 -30.411 1.00 120.46 ? 84 ASP B OD2 1 ATOM 4943 N N . PHE B 2 74 ? -27.588 -46.045 -28.487 1.00 141.95 ? 85 PHE B N 1 ATOM 4944 C CA . PHE B 2 74 ? -26.632 -44.959 -28.580 1.00 149.24 ? 85 PHE B CA 1 ATOM 4945 C C . PHE B 2 74 ? -25.988 -44.944 -29.953 1.00 136.51 ? 85 PHE B C 1 ATOM 4946 O O . PHE B 2 74 ? -25.759 -45.984 -30.573 1.00 131.41 ? 85 PHE B O 1 ATOM 4947 C CB . PHE B 2 74 ? -25.566 -45.048 -27.494 1.00 157.84 ? 85 PHE B CB 1 ATOM 4948 C CG . PHE B 2 74 ? -24.667 -43.852 -27.455 1.00 161.03 ? 85 PHE B CG 1 ATOM 4949 C CD1 . PHE B 2 74 ? -25.187 -42.598 -27.171 1.00 155.54 ? 85 PHE B CD1 1 ATOM 4950 C CD2 . PHE B 2 74 ? -23.316 -43.967 -27.719 1.00 161.23 ? 85 PHE B CD2 1 ATOM 4951 C CE1 . PHE B 2 74 ? -24.376 -41.485 -27.140 1.00 150.29 ? 85 PHE B CE1 1 ATOM 4952 C CE2 . PHE B 2 74 ? -22.500 -42.856 -27.687 1.00 157.59 ? 85 PHE B CE2 1 ATOM 4953 C CZ . PHE B 2 74 ? -23.033 -41.615 -27.396 1.00 151.64 ? 85 PHE B CZ 1 ATOM 4954 N N . GLU B 2 75 ? -25.715 -43.738 -30.425 1.00 127.32 ? 86 GLU B N 1 ATOM 4955 C CA . GLU B 2 75 ? -25.247 -43.546 -31.777 1.00 118.85 ? 86 GLU B CA 1 ATOM 4956 C C . GLU B 2 75 ? -23.755 -43.826 -31.845 1.00 123.30 ? 86 GLU B C 1 ATOM 4957 O O . GLU B 2 75 ? -22.953 -43.161 -31.191 1.00 127.37 ? 86 GLU B O 1 ATOM 4958 C CB . GLU B 2 75 ? -25.560 -42.111 -32.187 1.00 116.87 ? 86 GLU B CB 1 ATOM 4959 C CG . GLU B 2 75 ? -26.946 -41.680 -31.712 1.00 113.33 ? 86 GLU B CG 1 ATOM 4960 C CD . GLU B 2 75 ? -27.146 -40.173 -31.708 1.00 108.01 ? 86 GLU B CD 1 ATOM 4961 O OE1 . GLU B 2 75 ? -26.155 -39.438 -31.514 1.00 107.29 ? 86 GLU B OE1 1 ATOM 4962 O OE2 . GLU B 2 75 ? -28.302 -39.727 -31.876 1.00 97.86 ? 86 GLU B OE2 1 ATOM 4963 N N . GLU B 2 76 ? -23.392 -44.816 -32.654 1.00 124.25 ? 87 GLU B N 1 ATOM 4964 C CA . GLU B 2 76 ? -22.015 -45.008 -33.071 1.00 130.99 ? 87 GLU B CA 1 ATOM 4965 C C . GLU B 2 76 ? -21.763 -44.147 -34.297 1.00 128.58 ? 87 GLU B C 1 ATOM 4966 O O . GLU B 2 76 ? -22.604 -44.073 -35.192 1.00 123.95 ? 87 GLU B O 1 ATOM 4967 C CB . GLU B 2 76 ? -21.728 -46.488 -33.355 1.00 133.25 ? 87 GLU B CB 1 ATOM 4968 C CG . GLU B 2 76 ? -20.247 -46.848 -33.344 1.00 136.61 ? 87 GLU B CG 1 ATOM 4969 C CD . GLU B 2 76 ? -19.541 -46.544 -34.649 1.00 134.77 ? 87 GLU B CD 1 ATOM 4970 O OE1 . GLU B 2 76 ? -20.168 -46.691 -35.720 1.00 138.61 ? 87 GLU B OE1 1 ATOM 4971 O OE2 . GLU B 2 76 ? -18.357 -46.144 -34.603 1.00 131.28 ? 87 GLU B OE2 1 ATOM 4972 N N . PRO B 2 77 ? -20.605 -43.486 -34.346 1.00 126.99 ? 88 PRO B N 1 ATOM 4973 C CA . PRO B 2 77 ? -20.221 -42.801 -35.583 1.00 127.97 ? 88 PRO B CA 1 ATOM 4974 C C . PRO B 2 77 ? -19.870 -43.778 -36.709 1.00 135.64 ? 88 PRO B C 1 ATOM 4975 O O . PRO B 2 77 ? -18.728 -43.790 -37.140 1.00 140.56 ? 88 PRO B O 1 ATOM 4976 C CB . PRO B 2 77 ? -18.982 -41.997 -35.165 1.00 130.80 ? 88 PRO B CB 1 ATOM 4977 C CG . PRO B 2 77 ? -18.594 -42.523 -33.803 1.00 134.60 ? 88 PRO B CG 1 ATOM 4978 C CD . PRO B 2 77 ? -19.859 -42.977 -33.186 1.00 129.12 ? 88 PRO B CD 1 ATOM 4979 N N . ILE B 2 78 ? -20.835 -44.597 -37.130 1.00 136.26 ? 89 ILE B N 1 ATOM 4980 C CA . ILE B 2 78 ? -20.994 -45.122 -38.502 1.00 134.82 ? 89 ILE B CA 1 ATOM 4981 C C . ILE B 2 78 ? -19.741 -45.107 -39.416 1.00 134.67 ? 89 ILE B C 1 ATOM 4982 O O . ILE B 2 78 ? -19.283 -44.064 -39.891 1.00 127.39 ? 89 ILE B O 1 ATOM 4983 C CB . ILE B 2 78 ? -22.188 -44.398 -39.214 1.00 122.70 ? 89 ILE B CB 1 ATOM 4984 C CG1 . ILE B 2 78 ? -22.470 -44.989 -40.598 1.00 120.32 ? 89 ILE B CG1 1 ATOM 4985 C CG2 . ILE B 2 78 ? -21.999 -42.888 -39.256 1.00 121.21 ? 89 ILE B CG2 1 ATOM 4986 C CD1 . ILE B 2 78 ? -23.493 -44.189 -41.393 1.00 117.33 ? 89 ILE B CD1 1 ATOM 4987 N N . ALA B 2 79 ? -19.191 -46.302 -39.624 1.00 136.71 ? 90 ALA B N 1 ATOM 4988 C CA . ALA B 2 79 ? -17.919 -46.532 -40.315 1.00 125.80 ? 90 ALA B CA 1 ATOM 4989 C C . ALA B 2 79 ? -18.133 -46.729 -41.821 1.00 135.67 ? 90 ALA B C 1 ATOM 4990 O O . ALA B 2 79 ? -18.746 -47.710 -42.243 1.00 144.54 ? 90 ALA B O 1 ATOM 4991 C CB . ALA B 2 79 ? -17.203 -47.733 -39.721 1.00 117.81 ? 90 ALA B CB 1 ATOM 4992 N N . PHE B 2 80 ? -17.629 -45.790 -42.621 1.00 133.02 ? 91 PHE B N 1 ATOM 4993 C CA . PHE B 2 80 ? -17.763 -45.831 -44.081 1.00 132.53 ? 91 PHE B CA 1 ATOM 4994 C C . PHE B 2 80 ? -16.671 -46.623 -44.779 1.00 130.25 ? 91 PHE B C 1 ATOM 4995 O O . PHE B 2 80 ? -15.498 -46.528 -44.425 1.00 135.77 ? 91 PHE B O 1 ATOM 4996 C CB . PHE B 2 80 ? -17.722 -44.415 -44.670 1.00 126.52 ? 91 PHE B CB 1 ATOM 4997 C CG . PHE B 2 80 ? -18.788 -43.498 -44.164 1.00 135.72 ? 91 PHE B CG 1 ATOM 4998 C CD1 . PHE B 2 80 ? -19.999 -43.988 -43.719 1.00 139.10 ? 91 PHE B CD1 1 ATOM 4999 C CD2 . PHE B 2 80 ? -18.566 -42.132 -44.115 1.00 138.96 ? 91 PHE B CD2 1 ATOM 5000 C CE1 . PHE B 2 80 ? -20.977 -43.128 -43.258 1.00 133.35 ? 91 PHE B CE1 1 ATOM 5001 C CE2 . PHE B 2 80 ? -19.537 -41.272 -43.642 1.00 139.82 ? 91 PHE B CE2 1 ATOM 5002 C CZ . PHE B 2 80 ? -20.746 -41.769 -43.215 1.00 133.69 ? 91 PHE B CZ 1 ATOM 5003 N N . ASP B 2 81 ? -17.067 -47.418 -45.767 1.00 128.57 ? 92 ASP B N 1 ATOM 5004 C CA . ASP B 2 81 ? -16.143 -47.743 -46.838 1.00 131.84 ? 92 ASP B CA 1 ATOM 5005 C C . ASP B 2 81 ? -16.300 -46.665 -47.907 1.00 138.34 ? 92 ASP B C 1 ATOM 5006 O O . ASP B 2 81 ? -16.684 -45.538 -47.590 1.00 138.05 ? 92 ASP B O 1 ATOM 5007 C CB . ASP B 2 81 ? -16.438 -49.141 -47.395 1.00 138.31 ? 92 ASP B CB 1 ATOM 5008 C CG . ASP B 2 81 ? -17.827 -49.244 -48.020 1.00 136.19 ? 92 ASP B CG 1 ATOM 5009 O OD1 . ASP B 2 81 ? -17.990 -48.836 -49.188 1.00 132.31 ? 92 ASP B OD1 1 ATOM 5010 O OD2 . ASP B 2 81 ? -18.757 -49.730 -47.342 1.00 132.17 ? 92 ASP B OD2 1 ATOM 5011 N N . GLY B 2 82 ? -16.029 -46.993 -49.165 1.00 140.23 ? 93 GLY B N 1 ATOM 5012 C CA . GLY B 2 82 ? -16.199 -46.018 -50.228 1.00 137.13 ? 93 GLY B CA 1 ATOM 5013 C C . GLY B 2 82 ? -17.021 -46.573 -51.372 1.00 130.28 ? 93 GLY B C 1 ATOM 5014 O O . GLY B 2 82 ? -17.384 -45.856 -52.306 1.00 127.99 ? 93 GLY B O 1 ATOM 5015 N N . SER B 2 83 ? -17.330 -47.861 -51.278 1.00 128.01 ? 94 SER B N 1 ATOM 5016 C CA . SER B 2 83 ? -18.018 -48.571 -52.346 1.00 129.39 ? 94 SER B CA 1 ATOM 5017 C C . SER B 2 83 ? -19.526 -48.505 -52.182 1.00 126.32 ? 94 SER B C 1 ATOM 5018 O O . SER B 2 83 ? -20.208 -47.714 -52.836 1.00 121.26 ? 94 SER B O 1 ATOM 5019 C CB . SER B 2 83 ? -17.559 -50.031 -52.392 1.00 129.07 ? 94 SER B CB 1 ATOM 5020 O OG . SER B 2 83 ? -17.884 -50.707 -51.190 1.00 120.28 ? 94 SER B OG 1 ATOM 5021 N N . ARG B 2 84 ? -20.029 -49.342 -51.281 1.00 124.89 ? 95 ARG B N 1 ATOM 5022 C CA . ARG B 2 84 ? -21.447 -49.398 -50.961 1.00 118.84 ? 95 ARG B CA 1 ATOM 5023 C C . ARG B 2 84 ? -21.847 -48.165 -50.159 1.00 112.25 ? 95 ARG B C 1 ATOM 5024 O O . ARG B 2 84 ? -22.429 -47.223 -50.696 1.00 110.07 ? 95 ARG B O 1 ATOM 5025 C CB . ARG B 2 84 ? -21.760 -50.687 -50.188 1.00 113.08 ? 95 ARG B CB 1 ATOM 5026 C CG . ARG B 2 84 ? -23.217 -50.872 -49.792 1.00 106.58 ? 95 ARG B CG 1 ATOM 5027 C CD . ARG B 2 84 ? -23.481 -52.301 -49.326 1.00 105.14 ? 95 ARG B CD 1 ATOM 5028 N NE . ARG B 2 84 ? -23.153 -52.482 -47.916 1.00 101.63 ? 95 ARG B NE 1 ATOM 5029 C CZ . ARG B 2 84 ? -23.936 -52.099 -46.914 1.00 100.13 ? 95 ARG B CZ 1 ATOM 5030 N NH1 . ARG B 2 84 ? -25.096 -51.510 -47.170 1.00 94.62 ? 95 ARG B NH1 1 ATOM 5031 N NH2 . ARG B 2 84 ? -23.564 -52.313 -45.659 1.00 105.02 ? 95 ARG B NH2 1 ATOM 5032 N N . MET B 2 85 ? -21.530 -48.183 -48.870 1.00 109.08 ? 96 MET B N 1 ATOM 5033 C CA . MET B 2 85 ? -21.891 -47.101 -47.967 1.00 110.80 ? 96 MET B CA 1 ATOM 5034 C C . MET B 2 85 ? -20.878 -45.950 -48.047 1.00 122.85 ? 96 MET B C 1 ATOM 5035 O O . MET B 2 85 ? -20.032 -45.801 -47.164 1.00 124.75 ? 96 MET B O 1 ATOM 5036 C CB . MET B 2 85 ? -21.978 -47.665 -46.545 1.00 111.88 ? 96 MET B CB 1 ATOM 5037 C CG . MET B 2 85 ? -22.602 -46.779 -45.484 1.00 115.04 ? 96 MET B CG 1 ATOM 5038 S SD . MET B 2 85 ? -23.246 -47.804 -44.141 1.00 109.63 ? 96 MET B SD 1 ATOM 5039 C CE . MET B 2 85 ? -22.105 -49.189 -44.185 1.00 112.16 ? 96 MET B CE 1 ATOM 5040 N N . SER B 2 86 ? -20.960 -45.146 -49.108 1.00 124.93 ? 97 SER B N 1 ATOM 5041 C CA . SER B 2 86 ? -20.094 -43.972 -49.260 1.00 121.43 ? 97 SER B CA 1 ATOM 5042 C C . SER B 2 86 ? -20.662 -42.691 -48.640 1.00 116.30 ? 97 SER B C 1 ATOM 5043 O O . SER B 2 86 ? -21.806 -42.660 -48.190 1.00 118.84 ? 97 SER B O 1 ATOM 5044 C CB . SER B 2 86 ? -19.800 -43.737 -50.747 1.00 117.39 ? 97 SER B CB 1 ATOM 5045 O OG . SER B 2 86 ? -20.798 -42.936 -51.353 1.00 109.13 ? 97 SER B OG 1 ATOM 5046 N N . LYS B 2 87 ? -19.850 -41.635 -48.616 1.00 113.18 ? 98 LYS B N 1 ATOM 5047 C CA . LYS B 2 87 ? -20.283 -40.338 -48.091 1.00 117.88 ? 98 LYS B CA 1 ATOM 5048 C C . LYS B 2 87 ? -20.054 -39.166 -49.049 1.00 119.66 ? 98 LYS B C 1 ATOM 5049 O O . LYS B 2 87 ? -19.110 -38.401 -48.851 1.00 128.52 ? 98 LYS B O 1 ATOM 5050 C CB . LYS B 2 87 ? -19.603 -39.992 -46.767 1.00 129.13 ? 98 LYS B CB 1 ATOM 5051 C CG . LYS B 2 87 ? -20.246 -38.752 -46.120 1.00 129.09 ? 98 LYS B CG 1 ATOM 5052 C CD . LYS B 2 87 ? -19.233 -37.673 -45.757 1.00 129.21 ? 98 LYS B CD 1 ATOM 5053 C CE . LYS B 2 87 ? -19.775 -36.735 -44.689 1.00 114.37 ? 98 LYS B CE 1 ATOM 5054 N NZ . LYS B 2 87 ? -19.064 -35.424 -44.715 1.00 108.96 ? 98 LYS B NZ 1 ATOM 5055 N N . GLU B 2 88 ? -20.823 -39.037 -50.121 1.00 111.57 ? 99 GLU B N 1 ATOM 5056 C CA . GLU B 2 88 ? -20.586 -37.881 -50.980 1.00 112.28 ? 99 GLU B CA 1 ATOM 5057 C C . GLU B 2 88 ? -21.094 -36.627 -50.248 1.00 116.25 ? 99 GLU B C 1 ATOM 5058 O O . GLU B 2 88 ? -21.643 -36.732 -49.152 1.00 119.27 ? 99 GLU B O 1 ATOM 5059 C CB . GLU B 2 88 ? -21.212 -38.061 -52.362 1.00 110.94 ? 99 GLU B CB 1 ATOM 5060 C CG . GLU B 2 88 ? -20.630 -39.266 -53.100 1.00 103.76 ? 99 GLU B CG 1 ATOM 5061 C CD . GLU B 2 88 ? -21.560 -39.849 -54.143 1.00 101.17 ? 99 GLU B CD 1 ATOM 5062 O OE1 . GLU B 2 88 ? -22.251 -39.066 -54.829 1.00 100.28 ? 99 GLU B OE1 1 ATOM 5063 O OE2 . GLU B 2 88 ? -21.592 -41.090 -54.285 1.00 99.69 ? 99 GLU B OE2 1 ATOM 5064 N N . GLU B 2 89 ? -20.928 -35.457 -50.860 1.00 116.78 ? 100 GLU B N 1 ATOM 5065 C CA . GLU B 2 89 ? -20.836 -34.182 -50.127 1.00 123.17 ? 100 GLU B CA 1 ATOM 5066 C C . GLU B 2 89 ? -21.801 -33.925 -48.941 1.00 122.06 ? 100 GLU B C 1 ATOM 5067 O O . GLU B 2 89 ? -21.332 -33.817 -47.810 1.00 120.10 ? 100 GLU B O 1 ATOM 5068 C CB . GLU B 2 89 ? -20.930 -33.033 -51.145 1.00 121.50 ? 100 GLU B CB 1 ATOM 5069 C CG . GLU B 2 89 ? -22.280 -32.832 -51.814 1.00 116.75 ? 100 GLU B CG 1 ATOM 5070 C CD . GLU B 2 89 ? -22.185 -32.921 -53.320 1.00 120.26 ? 100 GLU B CD 1 ATOM 5071 O OE1 . GLU B 2 89 ? -21.048 -32.950 -53.840 1.00 127.74 ? 100 GLU B OE1 1 ATOM 5072 O OE2 . GLU B 2 89 ? -23.244 -32.967 -53.982 1.00 120.39 ? 100 GLU B OE2 1 ATOM 5073 N N . ASP B 2 90 ? -23.117 -33.883 -49.147 1.00 118.01 ? 101 ASP B N 1 ATOM 5074 C CA . ASP B 2 90 ? -24.010 -33.594 -48.026 1.00 111.33 ? 101 ASP B CA 1 ATOM 5075 C C . ASP B 2 90 ? -24.998 -34.713 -47.754 1.00 101.84 ? 101 ASP B C 1 ATOM 5076 O O . ASP B 2 90 ? -26.014 -34.510 -47.088 1.00 99.82 ? 101 ASP B O 1 ATOM 5077 C CB . ASP B 2 90 ? -24.790 -32.294 -48.270 1.00 114.83 ? 101 ASP B CB 1 ATOM 5078 C CG . ASP B 2 90 ? -25.954 -32.466 -49.247 1.00 112.71 ? 101 ASP B CG 1 ATOM 5079 O OD1 . ASP B 2 90 ? -26.927 -31.683 -49.154 1.00 114.57 ? 101 ASP B OD1 1 ATOM 5080 O OD2 . ASP B 2 90 ? -25.896 -33.362 -50.115 1.00 110.59 ? 101 ASP B OD2 1 ATOM 5081 N N . SER B 2 91 ? -24.677 -35.908 -48.230 1.00 99.50 ? 102 SER B N 1 ATOM 5082 C CA . SER B 2 91 ? -25.610 -37.015 -48.121 1.00 96.43 ? 102 SER B CA 1 ATOM 5083 C C . SER B 2 91 ? -24.859 -38.316 -47.917 1.00 97.69 ? 102 SER B C 1 ATOM 5084 O O . SER B 2 91 ? -23.629 -38.339 -47.903 1.00 105.67 ? 102 SER B O 1 ATOM 5085 C CB . SER B 2 91 ? -26.487 -37.108 -49.373 1.00 100.29 ? 102 SER B CB 1 ATOM 5086 O OG . SER B 2 91 ? -26.517 -35.883 -50.083 1.00 97.89 ? 102 SER B OG 1 ATOM 5087 N N . ILE B 2 92 ? -25.606 -39.401 -47.769 1.00 97.70 ? 103 ILE B N 1 ATOM 5088 C CA . ILE B 2 92 ? -25.028 -40.733 -47.751 1.00 106.90 ? 103 ILE B CA 1 ATOM 5089 C C . ILE B 2 92 ? -25.606 -41.550 -48.903 1.00 105.09 ? 103 ILE B C 1 ATOM 5090 O O . ILE B 2 92 ? -26.804 -41.486 -49.181 1.00 106.40 ? 103 ILE B O 1 ATOM 5091 C CB . ILE B 2 92 ? -25.244 -41.423 -46.389 1.00 110.13 ? 103 ILE B CB 1 ATOM 5092 C CG1 . ILE B 2 92 ? -24.357 -40.754 -45.334 1.00 109.70 ? 103 ILE B CG1 1 ATOM 5093 C CG2 . ILE B 2 92 ? -24.919 -42.902 -46.472 1.00 108.56 ? 103 ILE B CG2 1 ATOM 5094 C CD1 . ILE B 2 92 ? -24.371 -41.428 -43.978 1.00 107.31 ? 103 ILE B CD1 1 ATOM 5095 N N . TRP B 2 93 ? -24.750 -42.308 -49.576 1.00 104.66 ? 104 TRP B N 1 ATOM 5096 C CA . TRP B 2 93 ? -25.185 -43.182 -50.655 1.00 107.23 ? 104 TRP B CA 1 ATOM 5097 C C . TRP B 2 93 ? -25.079 -44.643 -50.227 1.00 107.68 ? 104 TRP B C 1 ATOM 5098 O O . TRP B 2 93 ? -24.050 -45.070 -49.704 1.00 110.00 ? 104 TRP B O 1 ATOM 5099 C CB . TRP B 2 93 ? -24.312 -42.926 -51.891 1.00 115.90 ? 104 TRP B CB 1 ATOM 5100 C CG . TRP B 2 93 ? -24.891 -42.002 -52.936 1.00 116.78 ? 104 TRP B CG 1 ATOM 5101 C CD1 . TRP B 2 93 ? -24.542 -40.698 -53.157 1.00 116.27 ? 104 TRP B CD1 1 ATOM 5102 C CD2 . TRP B 2 93 ? -25.820 -42.346 -53.973 1.00 115.01 ? 104 TRP B CD2 1 ATOM 5103 N NE1 . TRP B 2 93 ? -25.245 -40.192 -54.222 1.00 112.90 ? 104 TRP B NE1 1 ATOM 5104 C CE2 . TRP B 2 93 ? -26.031 -41.184 -54.746 1.00 112.88 ? 104 TRP B CE2 1 ATOM 5105 C CE3 . TRP B 2 93 ? -26.515 -43.514 -54.305 1.00 116.29 ? 104 TRP B CE3 1 ATOM 5106 C CZ2 . TRP B 2 93 ? -26.906 -41.158 -55.830 1.00 114.27 ? 104 TRP B CZ2 1 ATOM 5107 C CZ3 . TRP B 2 93 ? -27.382 -43.486 -55.382 1.00 117.24 ? 104 TRP B CZ3 1 ATOM 5108 C CH2 . TRP B 2 93 ? -27.571 -42.315 -56.131 1.00 115.08 ? 104 TRP B CH2 1 ATOM 5109 N N . PHE B 2 94 ? -26.149 -45.403 -50.442 1.00 104.40 ? 105 PHE B N 1 ATOM 5110 C CA . PHE B 2 94 ? -26.100 -46.850 -50.266 1.00 104.68 ? 105 PHE B CA 1 ATOM 5111 C C . PHE B 2 94 ? -26.227 -47.509 -51.621 1.00 96.48 ? 105 PHE B C 1 ATOM 5112 O O . PHE B 2 94 ? -27.127 -47.190 -52.394 1.00 90.01 ? 105 PHE B O 1 ATOM 5113 C CB . PHE B 2 94 ? -27.205 -47.385 -49.340 1.00 104.40 ? 105 PHE B CB 1 ATOM 5114 C CG . PHE B 2 94 ? -27.144 -46.874 -47.925 1.00 105.40 ? 105 PHE B CG 1 ATOM 5115 C CD1 . PHE B 2 94 ? -27.508 -45.578 -47.606 1.00 102.79 ? 105 PHE B CD1 1 ATOM 5116 C CD2 . PHE B 2 94 ? -26.716 -47.713 -46.907 1.00 105.23 ? 105 PHE B CD2 1 ATOM 5117 C CE1 . PHE B 2 94 ? -27.452 -45.134 -46.292 1.00 102.40 ? 105 PHE B CE1 1 ATOM 5118 C CE2 . PHE B 2 94 ? -26.651 -47.274 -45.600 1.00 102.01 ? 105 PHE B CE2 1 ATOM 5119 C CZ . PHE B 2 94 ? -27.017 -45.983 -45.290 1.00 102.83 ? 105 PHE B CZ 1 ATOM 5120 N N . ARG B 2 95 ? -25.308 -48.418 -51.915 1.00 97.75 ? 106 ARG B N 1 ATOM 5121 C CA . ARG B 2 95 ? -25.380 -49.161 -53.156 1.00 100.46 ? 106 ARG B CA 1 ATOM 5122 C C . ARG B 2 95 ? -24.712 -50.539 -53.064 1.00 105.36 ? 106 ARG B C 1 ATOM 5123 O O . ARG B 2 95 ? -23.496 -50.665 -53.218 1.00 107.80 ? 106 ARG B O 1 ATOM 5124 C CB . ARG B 2 95 ? -24.777 -48.303 -54.272 1.00 97.86 ? 106 ARG B CB 1 ATOM 5125 C CG . ARG B 2 95 ? -23.441 -47.675 -53.908 1.00 109.15 ? 106 ARG B CG 1 ATOM 5126 C CD . ARG B 2 95 ? -23.525 -46.153 -53.936 1.00 111.85 ? 106 ARG B CD 1 ATOM 5127 N NE . ARG B 2 95 ? -23.902 -45.615 -55.239 1.00 115.82 ? 106 ARG B NE 1 ATOM 5128 C CZ . ARG B 2 95 ? -23.585 -44.395 -55.662 1.00 114.02 ? 106 ARG B CZ 1 ATOM 5129 N NH1 . ARG B 2 95 ? -22.874 -43.586 -54.887 1.00 106.26 ? 106 ARG B NH1 1 ATOM 5130 N NH2 . ARG B 2 95 ? -23.983 -43.982 -56.857 1.00 119.40 ? 106 ARG B NH2 1 ATOM 5131 N N . PRO B 2 96 ? -25.519 -51.582 -52.802 1.00 101.23 ? 107 PRO B N 1 ATOM 5132 C CA . PRO B 2 96 ? -26.962 -51.438 -52.602 1.00 92.87 ? 107 PRO B CA 1 ATOM 5133 C C . PRO B 2 96 ? -27.302 -51.207 -51.134 1.00 88.93 ? 107 PRO B C 1 ATOM 5134 O O . PRO B 2 96 ? -26.433 -50.856 -50.335 1.00 88.78 ? 107 PRO B O 1 ATOM 5135 C CB . PRO B 2 96 ? -27.499 -52.785 -53.074 1.00 90.73 ? 107 PRO B CB 1 ATOM 5136 C CG . PRO B 2 96 ? -26.429 -53.748 -52.631 1.00 90.46 ? 107 PRO B CG 1 ATOM 5137 C CD . PRO B 2 96 ? -25.105 -52.995 -52.720 1.00 96.93 ? 107 PRO B CD 1 ATOM 5138 N N . THR B 2 97 ? -28.570 -51.400 -50.795 1.00 87.64 ? 108 THR B N 1 ATOM 5139 C CA . THR B 2 97 ? -29.033 -51.306 -49.421 1.00 89.93 ? 108 THR B CA 1 ATOM 5140 C C . THR B 2 97 ? -28.919 -52.706 -48.814 1.00 88.45 ? 108 THR B C 1 ATOM 5141 O O . THR B 2 97 ? -28.969 -53.704 -49.533 1.00 85.57 ? 108 THR B O 1 ATOM 5142 C CB . THR B 2 97 ? -30.477 -50.737 -49.328 1.00 86.30 ? 108 THR B CB 1 ATOM 5143 O OG1 . THR B 2 97 ? -30.516 -49.680 -48.361 1.00 77.57 ? 108 THR B OG1 1 ATOM 5144 C CG2 . THR B 2 97 ? -31.458 -51.795 -48.907 1.00 84.73 ? 108 THR B CG2 1 ATOM 5145 N N . LEU B 2 98 ? -28.742 -52.780 -47.501 1.00 89.62 ? 109 LEU B N 1 ATOM 5146 C CA . LEU B 2 98 ? -28.611 -54.058 -46.807 1.00 95.64 ? 109 LEU B CA 1 ATOM 5147 C C . LEU B 2 98 ? -29.597 -54.065 -45.650 1.00 101.68 ? 109 LEU B C 1 ATOM 5148 O O . LEU B 2 98 ? -30.015 -53.007 -45.194 1.00 103.38 ? 109 LEU B O 1 ATOM 5149 C CB . LEU B 2 98 ? -27.178 -54.298 -46.318 1.00 96.72 ? 109 LEU B CB 1 ATOM 5150 C CG . LEU B 2 98 ? -26.738 -55.763 -46.384 1.00 103.13 ? 109 LEU B CG 1 ATOM 5151 C CD1 . LEU B 2 98 ? -27.334 -56.443 -47.606 1.00 104.84 ? 109 LEU B CD1 1 ATOM 5152 C CD2 . LEU B 2 98 ? -25.222 -55.894 -46.389 1.00 109.06 ? 109 LEU B CD2 1 ATOM 5153 N N . LEU B 2 99 ? -30.016 -55.246 -45.209 1.00 100.43 ? 110 LEU B N 1 ATOM 5154 C CA . LEU B 2 99 ? -31.009 -55.329 -44.142 1.00 95.29 ? 110 LEU B CA 1 ATOM 5155 C C . LEU B 2 99 ? -30.511 -54.689 -42.851 1.00 94.72 ? 110 LEU B C 1 ATOM 5156 O O . LEU B 2 99 ? -31.284 -54.070 -42.119 1.00 98.05 ? 110 LEU B O 1 ATOM 5157 C CB . LEU B 2 99 ? -31.395 -56.783 -43.884 1.00 95.50 ? 110 LEU B CB 1 ATOM 5158 C CG . LEU B 2 99 ? -32.603 -57.311 -44.658 1.00 100.59 ? 110 LEU B CG 1 ATOM 5159 C CD1 . LEU B 2 99 ? -33.047 -58.644 -44.089 1.00 117.71 ? 110 LEU B CD1 1 ATOM 5160 C CD2 . LEU B 2 99 ? -33.744 -56.312 -44.587 1.00 91.37 ? 110 LEU B CD2 1 ATOM 5161 N N . GLN B 2 100 ? -29.223 -54.845 -42.565 1.00 92.31 ? 111 GLN B N 1 ATOM 5162 C CA . GLN B 2 100 ? -28.638 -54.241 -41.374 1.00 88.32 ? 111 GLN B CA 1 ATOM 5163 C C . GLN B 2 100 ? -28.512 -52.717 -41.496 1.00 85.82 ? 111 GLN B C 1 ATOM 5164 O O . GLN B 2 100 ? -28.123 -52.043 -40.543 1.00 82.16 ? 111 GLN B O 1 ATOM 5165 C CB . GLN B 2 100 ? -27.266 -54.867 -41.097 1.00 100.02 ? 111 GLN B CB 1 ATOM 5166 C CG . GLN B 2 100 ? -27.183 -56.341 -41.476 1.00 114.67 ? 111 GLN B CG 1 ATOM 5167 C CD . GLN B 2 100 ? -25.754 -56.824 -41.661 1.00 128.51 ? 111 GLN B CD 1 ATOM 5168 O OE1 . GLN B 2 100 ? -24.853 -56.036 -41.951 1.00 124.34 ? 111 GLN B OE1 1 ATOM 5169 N NE2 . GLN B 2 100 ? -25.541 -58.127 -41.497 1.00 140.63 ? 111 GLN B NE2 1 ATOM 5170 N N . ASP B 2 101 ? -28.833 -52.179 -42.671 1.00 93.68 ? 112 ASP B N 1 ATOM 5171 C CA . ASP B 2 101 ? -28.705 -50.739 -42.903 1.00 101.21 ? 112 ASP B CA 1 ATOM 5172 C C . ASP B 2 101 ? -29.878 -49.948 -42.315 1.00 90.47 ? 112 ASP B C 1 ATOM 5173 O O . ASP B 2 101 ? -29.856 -48.717 -42.294 1.00 90.46 ? 112 ASP B O 1 ATOM 5174 C CB . ASP B 2 101 ? -28.589 -50.443 -44.404 1.00 108.98 ? 112 ASP B CB 1 ATOM 5175 C CG . ASP B 2 101 ? -27.205 -50.752 -44.966 1.00 108.01 ? 112 ASP B CG 1 ATOM 5176 O OD1 . ASP B 2 101 ? -26.224 -50.729 -44.194 1.00 111.17 ? 112 ASP B OD1 1 ATOM 5177 O OD2 . ASP B 2 101 ? -27.095 -51.017 -46.185 1.00 99.00 ? 112 ASP B OD2 1 ATOM 5178 N N . SER B 2 102 ? -30.908 -50.659 -41.865 1.00 84.73 ? 113 SER B N 1 ATOM 5179 C CA . SER B 2 102 ? -32.093 -50.023 -41.294 1.00 80.74 ? 113 SER B CA 1 ATOM 5180 C C . SER B 2 102 ? -31.705 -49.280 -40.027 1.00 75.20 ? 113 SER B C 1 ATOM 5181 O O . SER B 2 102 ? -30.830 -49.730 -39.290 1.00 79.14 ? 113 SER B O 1 ATOM 5182 C CB . SER B 2 102 ? -33.189 -51.045 -40.998 1.00 95.60 ? 113 SER B CB 1 ATOM 5183 O OG . SER B 2 102 ? -33.645 -51.672 -42.182 1.00 97.79 ? 113 SER B OG 1 ATOM 5184 N N . GLY B 2 103 ? -32.337 -48.142 -39.768 1.00 73.39 ? 114 GLY B N 1 ATOM 5185 C CA . GLY B 2 103 ? -32.088 -47.444 -38.520 1.00 86.63 ? 114 GLY B CA 1 ATOM 5186 C C . GLY B 2 103 ? -32.318 -45.951 -38.594 1.00 88.66 ? 114 GLY B C 1 ATOM 5187 O O . GLY B 2 103 ? -32.874 -45.441 -39.566 1.00 85.72 ? 114 GLY B O 1 ATOM 5188 N N . LEU B 2 104 ? -31.883 -45.247 -37.554 1.00 92.03 ? 115 LEU B N 1 ATOM 5189 C CA . LEU B 2 104 ? -31.949 -43.797 -37.550 1.00 93.79 ? 115 LEU B CA 1 ATOM 5190 C C . LEU B 2 104 ? -30.537 -43.285 -37.790 1.00 103.93 ? 115 LEU B C 1 ATOM 5191 O O . LEU B 2 104 ? -29.572 -43.778 -37.202 1.00 106.52 ? 115 LEU B O 1 ATOM 5192 C CB . LEU B 2 104 ? -32.504 -43.265 -36.228 1.00 85.63 ? 115 LEU B CB 1 ATOM 5193 C CG . LEU B 2 104 ? -33.916 -43.695 -35.828 1.00 91.71 ? 115 LEU B CG 1 ATOM 5194 C CD1 . LEU B 2 104 ? -34.155 -43.401 -34.360 1.00 105.44 ? 115 LEU B CD1 1 ATOM 5195 C CD2 . LEU B 2 104 ? -34.948 -42.978 -36.679 1.00 91.07 ? 115 LEU B CD2 1 ATOM 5196 N N . TYR B 2 105 ? -30.429 -42.295 -38.667 1.00 101.46 ? 116 TYR B N 1 ATOM 5197 C CA . TYR B 2 105 ? -29.138 -41.760 -39.067 1.00 99.12 ? 116 TYR B CA 1 ATOM 5198 C C . TYR B 2 105 ? -29.017 -40.299 -38.659 1.00 98.94 ? 116 TYR B C 1 ATOM 5199 O O . TYR B 2 105 ? -29.512 -39.408 -39.353 1.00 97.77 ? 116 TYR B O 1 ATOM 5200 C CB . TYR B 2 105 ? -28.946 -41.940 -40.575 1.00 92.15 ? 116 TYR B CB 1 ATOM 5201 C CG . TYR B 2 105 ? -28.674 -43.384 -40.951 1.00 90.64 ? 116 TYR B CG 1 ATOM 5202 C CD1 . TYR B 2 105 ? -29.714 -44.305 -41.045 1.00 97.77 ? 116 TYR B CD1 1 ATOM 5203 C CD2 . TYR B 2 105 ? -27.380 -43.837 -41.174 1.00 90.27 ? 116 TYR B CD2 1 ATOM 5204 C CE1 . TYR B 2 105 ? -29.474 -45.631 -41.372 1.00 98.57 ? 116 TYR B CE1 1 ATOM 5205 C CE2 . TYR B 2 105 ? -27.129 -45.159 -41.503 1.00 95.15 ? 116 TYR B CE2 1 ATOM 5206 C CZ . TYR B 2 105 ? -28.180 -46.053 -41.600 1.00 97.36 ? 116 TYR B CZ 1 ATOM 5207 O OH . TYR B 2 105 ? -27.939 -47.368 -41.927 1.00 99.29 ? 116 TYR B OH 1 ATOM 5208 N N . ALA B 2 106 ? -28.360 -40.056 -37.528 1.00 95.28 ? 117 ALA B N 1 ATOM 5209 C CA . ALA B 2 106 ? -28.200 -38.697 -37.030 1.00 90.35 ? 117 ALA B CA 1 ATOM 5210 C C . ALA B 2 106 ? -27.191 -37.918 -37.861 1.00 93.89 ? 117 ALA B C 1 ATOM 5211 O O . ALA B 2 106 ? -26.164 -38.448 -38.282 1.00 94.15 ? 117 ALA B O 1 ATOM 5212 C CB . ALA B 2 106 ? -27.775 -38.716 -35.572 1.00 89.99 ? 117 ALA B CB 1 ATOM 5213 N N . CYS B 2 107 ? -27.503 -36.648 -38.086 1.00 95.35 ? 118 CYS B N 1 ATOM 5214 C CA . CYS B 2 107 ? -26.740 -35.795 -38.984 1.00 101.53 ? 118 CYS B CA 1 ATOM 5215 C C . CYS B 2 107 ? -26.352 -34.545 -38.201 1.00 107.88 ? 118 CYS B C 1 ATOM 5216 O O . CYS B 2 107 ? -27.213 -33.734 -37.868 1.00 105.89 ? 118 CYS B O 1 ATOM 5217 C CB . CYS B 2 107 ? -27.565 -35.457 -40.235 1.00 100.19 ? 118 CYS B CB 1 ATOM 5218 S SG . CYS B 2 107 ? -27.055 -33.995 -41.171 1.00 95.08 ? 118 CYS B SG 1 ATOM 5219 N N . VAL B 2 108 ? -25.065 -34.389 -37.905 1.00 113.69 ? 119 VAL B N 1 ATOM 5220 C CA . VAL B 2 108 ? -24.622 -33.341 -36.986 1.00 110.58 ? 119 VAL B CA 1 ATOM 5221 C C . VAL B 2 108 ? -23.773 -32.249 -37.653 1.00 117.14 ? 119 VAL B C 1 ATOM 5222 O O . VAL B 2 108 ? -22.995 -32.520 -38.568 1.00 120.28 ? 119 VAL B O 1 ATOM 5223 C CB . VAL B 2 108 ? -23.823 -33.963 -35.811 1.00 106.94 ? 119 VAL B CB 1 ATOM 5224 C CG1 . VAL B 2 108 ? -23.785 -33.020 -34.621 1.00 107.98 ? 119 VAL B CG1 1 ATOM 5225 C CG2 . VAL B 2 108 ? -24.436 -35.295 -35.405 1.00 112.36 ? 119 VAL B CG2 1 ATOM 5226 N N . ILE B 2 109 ? -23.955 -31.013 -37.186 1.00 117.75 ? 120 ILE B N 1 ATOM 5227 C CA . ILE B 2 109 ? -23.241 -29.836 -37.689 1.00 119.15 ? 120 ILE B CA 1 ATOM 5228 C C . ILE B 2 109 ? -22.652 -29.065 -36.497 1.00 124.28 ? 120 ILE B C 1 ATOM 5229 O O . ILE B 2 109 ? -23.243 -29.060 -35.416 1.00 127.23 ? 120 ILE B O 1 ATOM 5230 C CB . ILE B 2 109 ? -24.183 -28.932 -38.537 1.00 107.02 ? 120 ILE B CB 1 ATOM 5231 C CG1 . ILE B 2 109 ? -23.849 -29.056 -40.027 1.00 102.36 ? 120 ILE B CG1 1 ATOM 5232 C CG2 . ILE B 2 109 ? -24.151 -27.475 -38.078 1.00 116.25 ? 120 ILE B CG2 1 ATOM 5233 C CD1 . ILE B 2 109 ? -24.257 -30.379 -40.629 1.00 102.46 ? 120 ILE B CD1 1 ATOM 5234 N N . ARG B 2 110 ? -21.493 -28.427 -36.672 1.00 123.54 ? 121 ARG B N 1 ATOM 5235 C CA . ARG B 2 110 ? -20.767 -27.893 -35.517 1.00 125.00 ? 121 ARG B CA 1 ATOM 5236 C C . ARG B 2 110 ? -19.771 -26.758 -35.789 1.00 133.83 ? 121 ARG B C 1 ATOM 5237 O O . ARG B 2 110 ? -18.900 -26.876 -36.650 1.00 139.33 ? 121 ARG B O 1 ATOM 5238 C CB . ARG B 2 110 ? -20.019 -29.042 -34.840 1.00 126.68 ? 121 ARG B CB 1 ATOM 5239 C CG . ARG B 2 110 ? -19.369 -28.690 -33.523 1.00 134.69 ? 121 ARG B CG 1 ATOM 5240 C CD . ARG B 2 110 ? -18.510 -29.839 -33.067 1.00 142.92 ? 121 ARG B CD 1 ATOM 5241 N NE . ARG B 2 110 ? -19.239 -31.098 -33.108 1.00 154.16 ? 121 ARG B NE 1 ATOM 5242 C CZ . ARG B 2 110 ? -19.952 -31.575 -32.097 1.00 153.77 ? 121 ARG B CZ 1 ATOM 5243 N NH1 . ARG B 2 110 ? -20.016 -30.904 -30.955 1.00 137.91 ? 121 ARG B NH1 1 ATOM 5244 N NH2 . ARG B 2 110 ? -20.586 -32.733 -32.223 1.00 160.32 ? 121 ARG B NH2 1 ATOM 5245 N N . ASN B 2 111 ? -19.913 -25.663 -35.041 1.00 135.38 ? 122 ASN B N 1 ATOM 5246 C CA . ASN B 2 111 ? -18.848 -24.675 -34.869 1.00 133.61 ? 122 ASN B CA 1 ATOM 5247 C C . ASN B 2 111 ? -17.862 -25.224 -33.838 1.00 132.65 ? 122 ASN B C 1 ATOM 5248 O O . ASN B 2 111 ? -17.124 -26.179 -34.091 1.00 130.59 ? 122 ASN B O 1 ATOM 5249 C CB . ASN B 2 111 ? -19.405 -23.321 -34.382 1.00 132.27 ? 122 ASN B CB 1 ATOM 5250 C CG . ASN B 2 111 ? -19.333 -22.213 -35.436 1.00 139.44 ? 122 ASN B CG 1 ATOM 5251 O OD1 . ASN B 2 111 ? -18.245 -21.761 -35.795 1.00 133.53 ? 122 ASN B OD1 1 ATOM 5252 N ND2 . ASN B 2 111 ? -20.502 -21.745 -35.903 1.00 152.86 ? 122 ASN B ND2 1 ATOM 5253 N N . SER B 2 112 ? -17.874 -24.586 -32.673 1.00 134.74 ? 123 SER B N 1 ATOM 5254 C CA . SER B 2 112 ? -17.310 -25.105 -31.430 1.00 135.55 ? 123 SER B CA 1 ATOM 5255 C C . SER B 2 112 ? -18.075 -24.376 -30.333 1.00 137.79 ? 123 SER B C 1 ATOM 5256 O O . SER B 2 112 ? -17.852 -24.573 -29.137 1.00 136.80 ? 123 SER B O 1 ATOM 5257 C CB . SER B 2 112 ? -15.798 -24.877 -31.336 1.00 131.89 ? 123 SER B CB 1 ATOM 5258 O OG . SER B 2 112 ? -15.422 -23.624 -31.877 1.00 143.60 ? 123 SER B OG 1 ATOM 5259 N N . THR B 2 113 ? -18.989 -23.523 -30.793 1.00 141.85 ? 124 THR B N 1 ATOM 5260 C CA . THR B 2 113 ? -19.925 -22.773 -29.962 1.00 148.45 ? 124 THR B CA 1 ATOM 5261 C C . THR B 2 113 ? -21.343 -23.042 -30.463 1.00 152.07 ? 124 THR B C 1 ATOM 5262 O O . THR B 2 113 ? -22.297 -22.361 -30.086 1.00 152.92 ? 124 THR B O 1 ATOM 5263 C CB . THR B 2 113 ? -19.643 -21.253 -30.006 1.00 148.58 ? 124 THR B CB 1 ATOM 5264 O OG1 . THR B 2 113 ? -19.758 -20.778 -31.356 1.00 145.56 ? 124 THR B OG1 1 ATOM 5265 C CG2 . THR B 2 113 ? -18.245 -20.944 -29.486 1.00 135.90 ? 124 THR B CG2 1 ATOM 5266 N N . TYR B 2 114 ? -21.460 -24.053 -31.319 1.00 152.82 ? 125 TYR B N 1 ATOM 5267 C CA . TYR B 2 114 ? -22.666 -24.297 -32.102 1.00 151.09 ? 125 TYR B CA 1 ATOM 5268 C C . TYR B 2 114 ? -22.746 -25.789 -32.407 1.00 139.30 ? 125 TYR B C 1 ATOM 5269 O O . TYR B 2 114 ? -21.773 -26.393 -32.859 1.00 134.79 ? 125 TYR B O 1 ATOM 5270 C CB . TYR B 2 114 ? -22.628 -23.455 -33.387 1.00 150.95 ? 125 TYR B CB 1 ATOM 5271 C CG . TYR B 2 114 ? -23.904 -23.332 -34.201 1.00 141.18 ? 125 TYR B CG 1 ATOM 5272 C CD1 . TYR B 2 114 ? -24.247 -22.121 -34.789 1.00 144.37 ? 125 TYR B CD1 1 ATOM 5273 C CD2 . TYR B 2 114 ? -24.736 -24.421 -34.419 1.00 131.93 ? 125 TYR B CD2 1 ATOM 5274 C CE1 . TYR B 2 114 ? -25.392 -21.991 -35.545 1.00 146.12 ? 125 TYR B CE1 1 ATOM 5275 C CE2 . TYR B 2 114 ? -25.885 -24.302 -35.173 1.00 134.86 ? 125 TYR B CE2 1 ATOM 5276 C CZ . TYR B 2 114 ? -26.208 -23.086 -35.734 1.00 144.77 ? 125 TYR B CZ 1 ATOM 5277 O OH . TYR B 2 114 ? -27.353 -22.967 -36.486 1.00 159.97 ? 125 TYR B OH 1 ATOM 5278 N N . CYS B 2 115 ? -23.906 -26.382 -32.152 1.00 131.48 ? 126 CYS B N 1 ATOM 5279 C CA . CYS B 2 115 ? -24.089 -27.811 -32.346 1.00 120.38 ? 126 CYS B CA 1 ATOM 5280 C C . CYS B 2 115 ? -25.568 -28.124 -32.552 1.00 115.38 ? 126 CYS B C 1 ATOM 5281 O O . CYS B 2 115 ? -26.401 -27.805 -31.705 1.00 107.61 ? 126 CYS B O 1 ATOM 5282 C CB . CYS B 2 115 ? -23.529 -28.580 -31.146 1.00 118.63 ? 126 CYS B CB 1 ATOM 5283 S SG . CYS B 2 115 ? -23.258 -30.345 -31.414 1.00 111.99 ? 126 CYS B SG 1 ATOM 5284 N N . MET B 2 116 ? -25.890 -28.744 -33.684 1.00 118.86 ? 127 MET B N 1 ATOM 5285 C CA . MET B 2 116 ? -27.272 -29.084 -34.014 1.00 110.10 ? 127 MET B CA 1 ATOM 5286 C C . MET B 2 116 ? -27.360 -30.367 -34.833 1.00 105.88 ? 127 MET B C 1 ATOM 5287 O O . MET B 2 116 ? -26.587 -30.566 -35.771 1.00 106.81 ? 127 MET B O 1 ATOM 5288 C CB . MET B 2 116 ? -27.935 -27.935 -34.779 1.00 107.19 ? 127 MET B CB 1 ATOM 5289 C CG . MET B 2 116 ? -29.303 -28.274 -35.352 1.00 101.54 ? 127 MET B CG 1 ATOM 5290 S SD . MET B 2 116 ? -30.012 -26.909 -36.291 1.00 112.97 ? 127 MET B SD 1 ATOM 5291 C CE . MET B 2 116 ? -30.088 -25.636 -35.035 1.00 105.18 ? 127 MET B CE 1 ATOM 5292 N N . LYS B 2 117 ? -28.306 -31.234 -34.486 1.00 99.66 ? 128 LYS B N 1 ATOM 5293 C CA . LYS B 2 117 ? -28.479 -32.480 -35.222 1.00 97.79 ? 128 LYS B CA 1 ATOM 5294 C C . LYS B 2 117 ? -29.949 -32.870 -35.387 1.00 95.65 ? 128 LYS B C 1 ATOM 5295 O O . LYS B 2 117 ? -30.806 -32.479 -34.592 1.00 95.82 ? 128 LYS B O 1 ATOM 5296 C CB . LYS B 2 117 ? -27.708 -33.611 -34.535 1.00 100.69 ? 128 LYS B CB 1 ATOM 5297 C CG . LYS B 2 117 ? -28.323 -34.119 -33.238 1.00 98.70 ? 128 LYS B CG 1 ATOM 5298 C CD . LYS B 2 117 ? -27.301 -34.909 -32.431 1.00 101.18 ? 128 LYS B CD 1 ATOM 5299 C CE . LYS B 2 117 ? -27.961 -35.832 -31.419 1.00 90.87 ? 128 LYS B CE 1 ATOM 5300 N NZ . LYS B 2 117 ? -28.558 -37.035 -32.069 1.00 82.37 ? 128 LYS B NZ 1 ATOM 5301 N N . VAL B 2 118 ? -30.225 -33.630 -36.443 1.00 92.65 ? 129 VAL B N 1 ATOM 5302 C CA . VAL B 2 118 ? -31.544 -34.193 -36.698 1.00 87.94 ? 129 VAL B CA 1 ATOM 5303 C C . VAL B 2 118 ? -31.366 -35.680 -36.993 1.00 83.69 ? 129 VAL B C 1 ATOM 5304 O O . VAL B 2 118 ? -30.285 -36.115 -37.398 1.00 86.04 ? 129 VAL B O 1 ATOM 5305 C CB . VAL B 2 118 ? -32.258 -33.487 -37.885 1.00 83.91 ? 129 VAL B CB 1 ATOM 5306 C CG1 . VAL B 2 118 ? -31.775 -34.038 -39.220 1.00 100.16 ? 129 VAL B CG1 1 ATOM 5307 C CG2 . VAL B 2 118 ? -33.768 -33.609 -37.779 1.00 83.27 ? 129 VAL B CG2 1 ATOM 5308 N N . SER B 2 119 ? -32.409 -36.467 -36.761 1.00 83.78 ? 130 SER B N 1 ATOM 5309 C CA . SER B 2 119 ? -32.385 -37.879 -37.122 1.00 92.81 ? 130 SER B CA 1 ATOM 5310 C C . SER B 2 119 ? -33.248 -38.098 -38.352 1.00 100.51 ? 130 SER B C 1 ATOM 5311 O O . SER B 2 119 ? -34.284 -37.452 -38.516 1.00 98.89 ? 130 SER B O 1 ATOM 5312 C CB . SER B 2 119 ? -32.870 -38.755 -35.963 1.00 94.49 ? 130 SER B CB 1 ATOM 5313 O OG . SER B 2 119 ? -31.789 -39.437 -35.349 1.00 93.69 ? 130 SER B OG 1 ATOM 5314 N N . ILE B 2 120 ? -32.805 -38.992 -39.230 1.00 105.26 ? 131 ILE B N 1 ATOM 5315 C CA . ILE B 2 120 ? -33.595 -39.365 -40.394 1.00 99.51 ? 131 ILE B CA 1 ATOM 5316 C C . ILE B 2 120 ? -33.793 -40.878 -40.398 1.00 98.07 ? 131 ILE B C 1 ATOM 5317 O O . ILE B 2 120 ? -32.854 -41.640 -40.153 1.00 93.30 ? 131 ILE B O 1 ATOM 5318 C CB . ILE B 2 120 ? -32.938 -38.903 -41.710 1.00 83.03 ? 131 ILE B CB 1 ATOM 5319 C CG1 . ILE B 2 120 ? -32.198 -37.577 -41.498 1.00 83.64 ? 131 ILE B CG1 1 ATOM 5320 C CG2 . ILE B 2 120 ? -33.993 -38.754 -42.782 1.00 86.08 ? 131 ILE B CG2 1 ATOM 5321 C CD1 . ILE B 2 120 ? -31.828 -36.861 -42.775 1.00 88.60 ? 131 ILE B CD1 1 ATOM 5322 N N . SER B 2 121 ? -35.025 -41.304 -40.664 1.00 92.97 ? 132 SER B N 1 ATOM 5323 C CA . SER B 2 121 ? -35.426 -42.696 -40.482 1.00 87.00 ? 132 SER B CA 1 ATOM 5324 C C . SER B 2 121 ? -35.379 -43.501 -41.776 1.00 89.99 ? 132 SER B C 1 ATOM 5325 O O . SER B 2 121 ? -35.964 -43.113 -42.788 1.00 89.91 ? 132 SER B O 1 ATOM 5326 C CB . SER B 2 121 ? -36.834 -42.759 -39.884 1.00 88.36 ? 132 SER B CB 1 ATOM 5327 O OG . SER B 2 121 ? -37.224 -44.098 -39.635 1.00 87.16 ? 132 SER B OG 1 ATOM 5328 N N . LEU B 2 122 ? -34.686 -44.635 -41.721 1.00 91.53 ? 133 LEU B N 1 ATOM 5329 C CA . LEU B 2 122 ? -34.482 -45.494 -42.883 1.00 90.80 ? 133 LEU B CA 1 ATOM 5330 C C . LEU B 2 122 ? -34.943 -46.926 -42.614 1.00 90.99 ? 133 LEU B C 1 ATOM 5331 O O . LEU B 2 122 ? -34.473 -47.567 -41.673 1.00 90.40 ? 133 LEU B O 1 ATOM 5332 C CB . LEU B 2 122 ? -33.006 -45.494 -43.292 1.00 92.66 ? 133 LEU B CB 1 ATOM 5333 C CG . LEU B 2 122 ? -32.637 -46.423 -44.453 1.00 92.78 ? 133 LEU B CG 1 ATOM 5334 C CD1 . LEU B 2 122 ? -33.199 -45.895 -45.767 1.00 95.07 ? 133 LEU B CD1 1 ATOM 5335 C CD2 . LEU B 2 122 ? -31.132 -46.634 -44.548 1.00 96.48 ? 133 LEU B CD2 1 ATOM 5336 N N . THR B 2 123 ? -35.853 -47.425 -43.448 1.00 90.67 ? 134 THR B N 1 ATOM 5337 C CA . THR B 2 123 ? -36.386 -48.776 -43.293 1.00 89.37 ? 134 THR B CA 1 ATOM 5338 C C . THR B 2 123 ? -36.094 -49.657 -44.505 1.00 89.50 ? 134 THR B C 1 ATOM 5339 O O . THR B 2 123 ? -36.642 -49.444 -45.589 1.00 87.07 ? 134 THR B O 1 ATOM 5340 C CB . THR B 2 123 ? -37.911 -48.756 -43.056 1.00 83.32 ? 134 THR B CB 1 ATOM 5341 O OG1 . THR B 2 123 ? -38.220 -47.836 -42.003 1.00 92.00 ? 134 THR B OG1 1 ATOM 5342 C CG2 . THR B 2 123 ? -38.409 -50.137 -42.670 1.00 81.88 ? 134 THR B CG2 1 ATOM 5343 N N . VAL B 2 124 ? -35.227 -50.646 -44.313 1.00 87.59 ? 135 VAL B N 1 ATOM 5344 C CA . VAL B 2 124 ? -34.908 -51.618 -45.354 1.00 89.13 ? 135 VAL B CA 1 ATOM 5345 C C . VAL B 2 124 ? -35.851 -52.817 -45.249 1.00 89.56 ? 135 VAL B C 1 ATOM 5346 O O . VAL B 2 124 ? -35.775 -53.598 -44.300 1.00 88.89 ? 135 VAL B O 1 ATOM 5347 C CB . VAL B 2 124 ? -33.440 -52.087 -45.255 1.00 93.39 ? 135 VAL B CB 1 ATOM 5348 C CG1 . VAL B 2 124 ? -33.168 -53.207 -46.238 1.00 99.46 ? 135 VAL B CG1 1 ATOM 5349 C CG2 . VAL B 2 124 ? -32.489 -50.919 -45.481 1.00 93.76 ? 135 VAL B CG2 1 ATOM 5350 N N . GLY B 2 125 ? -36.744 -52.946 -46.228 1.00 91.80 ? 136 GLY B N 1 ATOM 5351 C CA . GLY B 2 125 ? -37.771 -53.971 -46.215 1.00 91.80 ? 136 GLY B CA 1 ATOM 5352 C C . GLY B 2 125 ? -37.597 -55.038 -47.280 1.00 87.72 ? 136 GLY B C 1 ATOM 5353 O O . GLY B 2 125 ? -36.748 -54.919 -48.164 1.00 85.23 ? 136 GLY B O 1 ATOM 5354 N N . GLU B 2 126 ? -38.408 -56.087 -47.194 1.00 87.14 ? 137 GLU B N 1 ATOM 5355 C CA . GLU B 2 126 ? -38.318 -57.202 -48.129 1.00 97.94 ? 137 GLU B CA 1 ATOM 5356 C C . GLU B 2 126 ? -39.623 -57.394 -48.894 1.00 98.94 ? 137 GLU B C 1 ATOM 5357 O O . GLU B 2 126 ? -40.697 -57.063 -48.394 1.00 96.07 ? 137 GLU B O 1 ATOM 5358 C CB . GLU B 2 126 ? -37.951 -58.490 -47.388 1.00 100.50 ? 137 GLU B CB 1 ATOM 5359 C CG . GLU B 2 126 ? -36.680 -58.394 -46.566 1.00 106.82 ? 137 GLU B CG 1 ATOM 5360 C CD . GLU B 2 126 ? -36.205 -59.745 -46.063 1.00 119.98 ? 137 GLU B CD 1 ATOM 5361 O OE1 . GLU B 2 126 ? -35.737 -60.558 -46.887 1.00 119.07 ? 137 GLU B OE1 1 ATOM 5362 O OE2 . GLU B 2 126 ? -36.308 -59.995 -44.845 1.00 126.17 ? 137 GLU B OE2 1 ATOM 5363 N N . ASN B 2 127 ? -39.519 -57.926 -50.107 1.00 102.71 ? 138 ASN B N 1 ATOM 5364 C CA . ASN B 2 127 ? -40.690 -58.217 -50.923 1.00 101.38 ? 138 ASN B CA 1 ATOM 5365 C C . ASN B 2 127 ? -41.657 -59.130 -50.190 1.00 96.30 ? 138 ASN B C 1 ATOM 5366 O O . ASN B 2 127 ? -41.238 -60.064 -49.511 1.00 98.51 ? 138 ASN B O 1 ATOM 5367 C CB . ASN B 2 127 ? -40.267 -58.859 -52.246 1.00 110.06 ? 138 ASN B CB 1 ATOM 5368 C CG . ASN B 2 127 ? -38.771 -59.121 -52.314 1.00 118.27 ? 138 ASN B CG 1 ATOM 5369 O OD1 . ASN B 2 127 ? -37.991 -58.214 -52.612 1.00 113.78 ? 138 ASN B OD1 1 ATOM 5370 N ND2 . ASN B 2 127 ? -38.361 -60.360 -52.022 1.00 124.64 ? 138 ASN B ND2 1 ATOM 5371 N N . ASP B 2 128 ? -42.950 -58.854 -50.313 1.00 95.47 ? 139 ASP B N 1 ATOM 5372 C CA . ASP B 2 128 ? -43.947 -59.711 -49.693 1.00 101.12 ? 139 ASP B CA 1 ATOM 5373 C C . ASP B 2 128 ? -44.013 -61.024 -50.467 1.00 109.71 ? 139 ASP B C 1 ATOM 5374 O O . ASP B 2 128 ? -43.908 -61.037 -51.695 1.00 106.21 ? 139 ASP B O 1 ATOM 5375 C CB . ASP B 2 128 ? -45.314 -59.024 -49.643 1.00 99.51 ? 139 ASP B CB 1 ATOM 5376 C CG . ASP B 2 128 ? -46.190 -59.554 -48.523 1.00 102.23 ? 139 ASP B CG 1 ATOM 5377 O OD1 . ASP B 2 128 ? -47.412 -59.294 -48.541 1.00 98.61 ? 139 ASP B OD1 1 ATOM 5378 O OD2 . ASP B 2 128 ? -45.655 -60.236 -47.625 1.00 109.26 ? 139 ASP B OD2 1 ATOM 5379 N N . THR B 2 129 ? -44.175 -62.116 -49.722 1.00 118.71 ? 140 THR B N 1 ATOM 5380 C CA . THR B 2 129 ? -44.114 -63.492 -50.228 1.00 121.68 ? 140 THR B CA 1 ATOM 5381 C C . THR B 2 129 ? -44.723 -63.724 -51.619 1.00 115.46 ? 140 THR B C 1 ATOM 5382 O O . THR B 2 129 ? -45.941 -63.831 -51.765 1.00 121.98 ? 140 THR B O 1 ATOM 5383 C CB . THR B 2 129 ? -44.809 -64.460 -49.235 1.00 137.25 ? 140 THR B CB 1 ATOM 5384 O OG1 . THR B 2 129 ? -46.203 -64.141 -49.147 1.00 146.92 ? 140 THR B OG1 1 ATOM 5385 C CG2 . THR B 2 129 ? -44.179 -64.358 -47.848 1.00 121.00 ? 140 THR B CG2 1 ATOM 5386 N N . GLY B 2 130 ? -43.866 -63.805 -52.634 1.00 106.18 ? 141 GLY B N 1 ATOM 5387 C CA . GLY B 2 130 ? -44.303 -64.121 -53.986 1.00 115.34 ? 141 GLY B CA 1 ATOM 5388 C C . GLY B 2 130 ? -44.347 -62.948 -54.949 1.00 114.19 ? 141 GLY B C 1 ATOM 5389 O O . GLY B 2 130 ? -44.629 -63.120 -56.135 1.00 122.63 ? 141 GLY B O 1 ATOM 5390 N N . LEU B 2 131 ? -44.053 -61.756 -54.443 1.00 104.19 ? 142 LEU B N 1 ATOM 5391 C CA . LEU B 2 131 ? -44.219 -60.534 -55.221 1.00 100.86 ? 142 LEU B CA 1 ATOM 5392 C C . LEU B 2 131 ? -42.900 -59.782 -55.421 1.00 100.87 ? 142 LEU B C 1 ATOM 5393 O O . LEU B 2 131 ? -41.819 -60.302 -55.126 1.00 100.53 ? 142 LEU B O 1 ATOM 5394 C CB . LEU B 2 131 ? -45.255 -59.640 -54.536 1.00 93.80 ? 142 LEU B CB 1 ATOM 5395 C CG . LEU B 2 131 ? -46.524 -60.429 -54.180 1.00 88.56 ? 142 LEU B CG 1 ATOM 5396 C CD1 . LEU B 2 131 ? -47.369 -59.735 -53.127 1.00 89.70 ? 142 LEU B CD1 1 ATOM 5397 C CD2 . LEU B 2 131 ? -47.344 -60.708 -55.433 1.00 91.43 ? 142 LEU B CD2 1 ATOM 5398 N N . CYS B 2 132 ? -42.996 -58.561 -55.941 1.00 102.42 ? 143 CYS B N 1 ATOM 5399 C CA . CYS B 2 132 ? -41.830 -57.704 -56.153 1.00 96.97 ? 143 CYS B CA 1 ATOM 5400 C C . CYS B 2 132 ? -41.840 -56.532 -55.174 1.00 97.79 ? 143 CYS B C 1 ATOM 5401 O O . CYS B 2 132 ? -40.802 -56.143 -54.634 1.00 89.95 ? 143 CYS B O 1 ATOM 5402 C CB . CYS B 2 132 ? -41.793 -57.192 -57.598 1.00 104.71 ? 143 CYS B CB 1 ATOM 5403 S SG . CYS B 2 132 ? -43.322 -56.392 -58.184 1.00 110.83 ? 143 CYS B SG 1 ATOM 5404 N N . TYR B 2 133 ? -43.028 -55.973 -54.962 1.00 99.49 ? 144 TYR B N 1 ATOM 5405 C CA . TYR B 2 133 ? -43.230 -54.910 -53.988 1.00 85.11 ? 144 TYR B CA 1 ATOM 5406 C C . TYR B 2 133 ? -43.245 -55.450 -52.567 1.00 93.46 ? 144 TYR B C 1 ATOM 5407 O O . TYR B 2 133 ? -43.348 -56.656 -52.348 1.00 102.29 ? 144 TYR B O 1 ATOM 5408 C CB . TYR B 2 133 ? -44.544 -54.168 -54.260 1.00 76.62 ? 144 TYR B CB 1 ATOM 5409 C CG . TYR B 2 133 ? -45.772 -55.049 -54.358 1.00 82.49 ? 144 TYR B CG 1 ATOM 5410 C CD1 . TYR B 2 133 ? -46.393 -55.541 -53.217 1.00 83.34 ? 144 TYR B CD1 1 ATOM 5411 C CD2 . TYR B 2 133 ? -46.323 -55.371 -55.592 1.00 90.15 ? 144 TYR B CD2 1 ATOM 5412 C CE1 . TYR B 2 133 ? -47.516 -56.339 -53.301 1.00 86.83 ? 144 TYR B CE1 1 ATOM 5413 C CE2 . TYR B 2 133 ? -47.449 -56.171 -55.687 1.00 91.36 ? 144 TYR B CE2 1 ATOM 5414 C CZ . TYR B 2 133 ? -48.041 -56.651 -54.537 1.00 88.69 ? 144 TYR B CZ 1 ATOM 5415 O OH . TYR B 2 133 ? -49.162 -57.447 -54.613 1.00 90.57 ? 144 TYR B OH 1 ATOM 5416 N N . ASN B 2 134 ? -43.150 -54.543 -51.603 1.00 90.59 ? 145 ASN B N 1 ATOM 5417 C CA . ASN B 2 134 ? -43.454 -54.867 -50.219 1.00 86.60 ? 145 ASN B CA 1 ATOM 5418 C C . ASN B 2 134 ? -44.853 -54.354 -49.903 1.00 86.01 ? 145 ASN B C 1 ATOM 5419 O O . ASN B 2 134 ? -45.130 -53.163 -50.046 1.00 88.18 ? 145 ASN B O 1 ATOM 5420 C CB . ASN B 2 134 ? -42.417 -54.264 -49.271 1.00 83.12 ? 145 ASN B CB 1 ATOM 5421 C CG . ASN B 2 134 ? -42.741 -54.514 -47.815 1.00 83.09 ? 145 ASN B CG 1 ATOM 5422 O OD1 . ASN B 2 134 ? -43.548 -53.803 -47.218 1.00 80.54 ? 145 ASN B OD1 1 ATOM 5423 N ND2 . ASN B 2 134 ? -42.109 -55.524 -47.233 1.00 97.28 ? 145 ASN B ND2 1 ATOM 5424 N N . SER B 2 135 ? -45.731 -55.265 -49.495 1.00 88.56 ? 146 SER B N 1 ATOM 5425 C CA . SER B 2 135 ? -47.139 -54.960 -49.233 1.00 94.73 ? 146 SER B CA 1 ATOM 5426 C C . SER B 2 135 ? -47.363 -53.760 -48.307 1.00 96.48 ? 146 SER B C 1 ATOM 5427 O O . SER B 2 135 ? -48.323 -53.003 -48.474 1.00 96.44 ? 146 SER B O 1 ATOM 5428 C CB . SER B 2 135 ? -47.829 -56.188 -48.635 1.00 94.95 ? 146 SER B CB 1 ATOM 5429 O OG . SER B 2 135 ? -47.946 -57.229 -49.590 1.00 96.80 ? 146 SER B OG 1 ATOM 5430 N N . LYS B 2 136 ? -46.472 -53.595 -47.336 1.00 93.72 ? 147 LYS B N 1 ATOM 5431 C CA . LYS B 2 136 ? -46.606 -52.558 -46.316 1.00 89.88 ? 147 LYS B CA 1 ATOM 5432 C C . LYS B 2 136 ? -45.855 -51.273 -46.670 1.00 82.17 ? 147 LYS B C 1 ATOM 5433 O O . LYS B 2 136 ? -45.765 -50.356 -45.852 1.00 80.82 ? 147 LYS B O 1 ATOM 5434 C CB . LYS B 2 136 ? -46.104 -53.093 -44.971 1.00 100.08 ? 147 LYS B CB 1 ATOM 5435 C CG . LYS B 2 136 ? -46.689 -54.449 -44.594 1.00 106.37 ? 147 LYS B CG 1 ATOM 5436 C CD . LYS B 2 136 ? -45.674 -55.334 -43.887 1.00 96.40 ? 147 LYS B CD 1 ATOM 5437 C CE . LYS B 2 136 ? -46.233 -56.731 -43.654 1.00 88.10 ? 147 LYS B CE 1 ATOM 5438 N NZ . LYS B 2 136 ? -45.175 -57.683 -43.215 1.00 64.28 ? 147 LYS B NZ 1 ATOM 5439 N N . MET B 2 137 ? -45.325 -51.203 -47.889 1.00 79.40 ? 148 MET B N 1 ATOM 5440 C CA . MET B 2 137 ? -44.414 -50.121 -48.261 1.00 75.42 ? 148 MET B CA 1 ATOM 5441 C C . MET B 2 137 ? -44.756 -49.471 -49.603 1.00 60.87 ? 148 MET B C 1 ATOM 5442 O O . MET B 2 137 ? -43.881 -48.935 -50.283 1.00 57.49 ? 148 MET B O 1 ATOM 5443 C CB . MET B 2 137 ? -42.979 -50.653 -48.294 1.00 80.46 ? 148 MET B CB 1 ATOM 5444 C CG . MET B 2 137 ? -41.933 -49.718 -47.711 1.00 80.52 ? 148 MET B CG 1 ATOM 5445 S SD . MET B 2 137 ? -40.513 -50.642 -47.090 1.00 79.58 ? 148 MET B SD 1 ATOM 5446 C CE . MET B 2 137 ? -40.070 -51.608 -48.533 1.00 88.10 ? 148 MET B CE 1 ATOM 5447 N N . LYS B 2 138 ? -46.028 -49.512 -49.981 1.00 56.09 ? 149 LYS B N 1 ATOM 5448 C CA . LYS B 2 138 ? -46.459 -48.936 -51.252 1.00 54.98 ? 149 LYS B CA 1 ATOM 5449 C C . LYS B 2 138 ? -47.326 -47.691 -51.072 1.00 60.70 ? 149 LYS B C 1 ATOM 5450 O O . LYS B 2 138 ? -48.081 -47.589 -50.106 1.00 68.56 ? 149 LYS B O 1 ATOM 5451 C CB . LYS B 2 138 ? -47.222 -49.979 -52.071 1.00 66.08 ? 149 LYS B CB 1 ATOM 5452 C CG . LYS B 2 138 ? -48.261 -50.761 -51.287 1.00 71.21 ? 149 LYS B CG 1 ATOM 5453 C CD . LYS B 2 138 ? -49.344 -51.303 -52.205 1.00 70.63 ? 149 LYS B CD 1 ATOM 5454 C CE . LYS B 2 138 ? -49.731 -52.716 -51.826 1.00 71.15 ? 149 LYS B CE 1 ATOM 5455 N NZ . LYS B 2 138 ? -48.714 -53.685 -52.288 1.00 76.47 ? 149 LYS B NZ 1 ATOM 5456 N N . TYR B 2 139 ? -47.222 -46.757 -52.018 1.00 65.59 ? 150 TYR B N 1 ATOM 5457 C CA . TYR B 2 139 ? -48.035 -45.540 -52.026 1.00 60.37 ? 150 TYR B CA 1 ATOM 5458 C C . TYR B 2 139 ? -49.518 -45.860 -52.177 1.00 59.12 ? 150 TYR B C 1 ATOM 5459 O O . TYR B 2 139 ? -49.916 -47.025 -52.190 1.00 63.21 ? 150 TYR B O 1 ATOM 5460 C CB . TYR B 2 139 ? -47.611 -44.602 -53.163 1.00 71.22 ? 150 TYR B CB 1 ATOM 5461 C CG . TYR B 2 139 ? -46.150 -44.202 -53.166 1.00 87.78 ? 150 TYR B CG 1 ATOM 5462 C CD1 . TYR B 2 139 ? -45.702 -43.126 -52.410 1.00 93.36 ? 150 TYR B CD1 1 ATOM 5463 C CD2 . TYR B 2 139 ? -45.221 -44.890 -53.941 1.00 93.17 ? 150 TYR B CD2 1 ATOM 5464 C CE1 . TYR B 2 139 ? -44.366 -42.752 -52.414 1.00 97.45 ? 150 TYR B CE1 1 ATOM 5465 C CE2 . TYR B 2 139 ? -43.882 -44.524 -53.954 1.00 94.74 ? 150 TYR B CE2 1 ATOM 5466 C CZ . TYR B 2 139 ? -43.461 -43.454 -53.189 1.00 94.61 ? 150 TYR B CZ 1 ATOM 5467 O OH . TYR B 2 139 ? -42.132 -43.091 -53.202 1.00 94.53 ? 150 TYR B OH 1 ATOM 5468 N N . PHE B 2 140 ? -50.332 -44.819 -52.315 1.00 58.43 ? 151 PHE B N 1 ATOM 5469 C CA . PHE B 2 140 ? -51.764 -44.999 -52.517 1.00 71.96 ? 151 PHE B CA 1 ATOM 5470 C C . PHE B 2 140 ? -52.378 -43.893 -53.362 1.00 80.40 ? 151 PHE B C 1 ATOM 5471 O O . PHE B 2 140 ? -52.129 -42.707 -53.140 1.00 81.90 ? 151 PHE B O 1 ATOM 5472 C CB . PHE B 2 140 ? -52.478 -45.095 -51.169 1.00 78.53 ? 151 PHE B CB 1 ATOM 5473 C CG . PHE B 2 140 ? -52.251 -46.403 -50.469 1.00 85.41 ? 151 PHE B CG 1 ATOM 5474 C CD1 . PHE B 2 140 ? -52.862 -47.558 -50.928 1.00 88.82 ? 151 PHE B CD1 1 ATOM 5475 C CD2 . PHE B 2 140 ? -51.402 -46.487 -49.377 1.00 85.38 ? 151 PHE B CD2 1 ATOM 5476 C CE1 . PHE B 2 140 ? -52.648 -48.771 -50.301 1.00 91.98 ? 151 PHE B CE1 1 ATOM 5477 C CE2 . PHE B 2 140 ? -51.183 -47.699 -48.743 1.00 85.78 ? 151 PHE B CE2 1 ATOM 5478 C CZ . PHE B 2 140 ? -51.807 -48.843 -49.206 1.00 91.50 ? 151 PHE B CZ 1 ATOM 5479 N N . GLU B 2 141 ? -53.175 -44.308 -54.343 1.00 83.56 ? 152 GLU B N 1 ATOM 5480 C CA . GLU B 2 141 ? -53.852 -43.400 -55.262 1.00 87.93 ? 152 GLU B CA 1 ATOM 5481 C C . GLU B 2 141 ? -55.303 -43.838 -55.448 1.00 88.86 ? 152 GLU B C 1 ATOM 5482 O O . GLU B 2 141 ? -55.683 -44.936 -55.041 1.00 87.26 ? 152 GLU B O 1 ATOM 5483 C CB . GLU B 2 141 ? -53.131 -43.356 -56.616 1.00 82.12 ? 152 GLU B CB 1 ATOM 5484 C CG . GLU B 2 141 ? -51.768 -42.660 -56.592 1.00 80.84 ? 152 GLU B CG 1 ATOM 5485 C CD . GLU B 2 141 ? -51.875 -41.145 -56.445 1.00 84.05 ? 152 GLU B CD 1 ATOM 5486 O OE1 . GLU B 2 141 ? -52.928 -40.580 -56.813 1.00 83.96 ? 152 GLU B OE1 1 ATOM 5487 O OE2 . GLU B 2 141 ? -50.908 -40.518 -55.956 1.00 82.29 ? 152 GLU B OE2 1 ATOM 5488 N N . LYS B 2 142 ? -56.112 -42.977 -56.057 1.00 88.95 ? 153 LYS B N 1 ATOM 5489 C CA . LYS B 2 142 ? -57.496 -43.318 -56.369 1.00 96.48 ? 153 LYS B CA 1 ATOM 5490 C C . LYS B 2 142 ? -57.933 -42.658 -57.674 1.00 94.09 ? 153 LYS B C 1 ATOM 5491 O O . LYS B 2 142 ? -57.430 -41.597 -58.044 1.00 83.16 ? 153 LYS B O 1 ATOM 5492 C CB . LYS B 2 142 ? -58.435 -42.914 -55.227 1.00 96.31 ? 153 LYS B CB 1 ATOM 5493 C CG . LYS B 2 142 ? -58.556 -41.418 -54.990 1.00 99.39 ? 153 LYS B CG 1 ATOM 5494 C CD . LYS B 2 142 ? -59.764 -41.104 -54.123 1.00 100.37 ? 153 LYS B CD 1 ATOM 5495 C CE . LYS B 2 142 ? -59.664 -41.778 -52.762 1.00 106.18 ? 153 LYS B CE 1 ATOM 5496 N NZ . LYS B 2 142 ? -60.832 -41.445 -51.894 1.00 97.25 ? 153 LYS B NZ 1 ATOM 5497 N N . ALA B 2 143 ? -58.871 -43.297 -58.367 1.00 94.68 ? 154 ALA B N 1 ATOM 5498 C CA . ALA B 2 143 ? -59.330 -42.827 -59.670 1.00 89.49 ? 154 ALA B CA 1 ATOM 5499 C C . ALA B 2 143 ? -60.824 -43.059 -59.854 1.00 88.36 ? 154 ALA B C 1 ATOM 5500 O O . ALA B 2 143 ? -61.463 -43.723 -59.040 1.00 84.32 ? 154 ALA B O 1 ATOM 5501 C CB . ALA B 2 143 ? -58.555 -43.514 -60.776 1.00 88.50 ? 154 ALA B CB 1 ATOM 5502 N N . GLU B 2 144 ? -61.371 -42.515 -60.936 1.00 91.28 ? 155 GLU B N 1 ATOM 5503 C CA . GLU B 2 144 ? -62.796 -42.635 -61.217 1.00 95.20 ? 155 GLU B CA 1 ATOM 5504 C C . GLU B 2 144 ? -63.061 -43.265 -62.577 1.00 98.59 ? 155 GLU B C 1 ATOM 5505 O O . GLU B 2 144 ? -62.335 -43.016 -63.539 1.00 96.99 ? 155 GLU B O 1 ATOM 5506 C CB . GLU B 2 144 ? -63.470 -41.265 -61.160 1.00 93.15 ? 155 GLU B CB 1 ATOM 5507 C CG . GLU B 2 144 ? -63.268 -40.520 -59.860 1.00 93.67 ? 155 GLU B CG 1 ATOM 5508 C CD . GLU B 2 144 ? -63.872 -39.132 -59.894 1.00 98.55 ? 155 GLU B CD 1 ATOM 5509 O OE1 . GLU B 2 144 ? -63.173 -38.197 -60.337 1.00 103.39 ? 155 GLU B OE1 1 ATOM 5510 O OE2 . GLU B 2 144 ? -65.042 -38.979 -59.487 1.00 96.46 ? 155 GLU B OE2 1 ATOM 5511 N N . LEU B 2 145 ? -64.113 -44.075 -62.647 1.00 95.68 ? 156 LEU B N 1 ATOM 5512 C CA . LEU B 2 145 ? -64.591 -44.604 -63.916 1.00 88.53 ? 156 LEU B CA 1 ATOM 5513 C C . LEU B 2 145 ? -64.967 -43.460 -64.859 1.00 94.55 ? 156 LEU B C 1 ATOM 5514 O O . LEU B 2 145 ? -65.524 -42.447 -64.430 1.00 97.82 ? 156 LEU B O 1 ATOM 5515 C CB . LEU B 2 145 ? -65.792 -45.529 -63.695 1.00 79.40 ? 156 LEU B CB 1 ATOM 5516 C CG . LEU B 2 145 ? -65.531 -46.808 -62.894 1.00 80.09 ? 156 LEU B CG 1 ATOM 5517 C CD1 . LEU B 2 145 ? -66.814 -47.601 -62.703 1.00 83.09 ? 156 LEU B CD1 1 ATOM 5518 C CD2 . LEU B 2 145 ? -64.484 -47.654 -63.584 1.00 85.80 ? 156 LEU B CD2 1 ATOM 5519 N N . SER B 2 146 ? -64.636 -43.627 -66.137 1.00 97.30 ? 157 SER B N 1 ATOM 5520 C CA . SER B 2 146 ? -64.960 -42.661 -67.189 1.00 106.35 ? 157 SER B CA 1 ATOM 5521 C C . SER B 2 146 ? -64.284 -41.300 -66.986 1.00 95.54 ? 157 SER B C 1 ATOM 5522 O O . SER B 2 146 ? -64.721 -40.293 -67.545 1.00 94.94 ? 157 SER B O 1 ATOM 5523 C CB . SER B 2 146 ? -66.480 -42.483 -67.298 1.00 108.94 ? 157 SER B CB 1 ATOM 5524 O OG . SER B 2 146 ? -66.827 -41.565 -68.320 1.00 114.45 ? 157 SER B OG 1 ATOM 5525 N N . LYS B 2 147 ? -63.215 -41.275 -66.194 1.00 84.35 ? 158 LYS B N 1 ATOM 5526 C CA . LYS B 2 147 ? -62.423 -40.061 -66.008 1.00 80.72 ? 158 LYS B CA 1 ATOM 5527 C C . LYS B 2 147 ? -60.928 -40.385 -65.956 1.00 78.17 ? 158 LYS B C 1 ATOM 5528 O O . LYS B 2 147 ? -60.537 -41.504 -65.623 1.00 75.56 ? 158 LYS B O 1 ATOM 5529 C CB . LYS B 2 147 ? -62.869 -39.312 -64.746 1.00 96.25 ? 158 LYS B CB 1 ATOM 5530 C CG . LYS B 2 147 ? -64.238 -38.645 -64.891 1.00 101.02 ? 158 LYS B CG 1 ATOM 5531 C CD . LYS B 2 147 ? -64.558 -37.698 -63.748 1.00 108.45 ? 158 LYS B CD 1 ATOM 5532 C CE . LYS B 2 147 ? -65.923 -37.048 -63.946 1.00 95.01 ? 158 LYS B CE 1 ATOM 5533 N NZ . LYS B 2 147 ? -66.219 -36.023 -62.905 1.00 74.74 ? 158 LYS B NZ 1 ATOM 5534 N N . SER B 2 148 ? -60.100 -39.395 -66.283 1.00 75.05 ? 159 SER B N 1 ATOM 5535 C CA . SER B 2 148 ? -58.675 -39.616 -66.537 1.00 76.09 ? 159 SER B CA 1 ATOM 5536 C C . SER B 2 148 ? -57.781 -39.444 -65.309 1.00 73.93 ? 159 SER B C 1 ATOM 5537 O O . SER B 2 148 ? -57.727 -38.372 -64.706 1.00 74.49 ? 159 SER B O 1 ATOM 5538 C CB . SER B 2 148 ? -58.194 -38.675 -67.644 1.00 84.53 ? 159 SER B CB 1 ATOM 5539 O OG . SER B 2 148 ? -58.218 -37.327 -67.214 1.00 84.80 ? 159 SER B OG 1 ATOM 5540 N N . LYS B 2 149 ? -57.060 -40.507 -64.965 1.00 72.83 ? 160 LYS B N 1 ATOM 5541 C CA . LYS B 2 149 ? -56.126 -40.493 -63.844 1.00 81.05 ? 160 LYS B CA 1 ATOM 5542 C C . LYS B 2 149 ? -54.685 -40.532 -64.337 1.00 72.46 ? 160 LYS B C 1 ATOM 5543 O O . LYS B 2 149 ? -54.375 -41.221 -65.309 1.00 79.62 ? 160 LYS B O 1 ATOM 5544 C CB . LYS B 2 149 ? -56.391 -41.680 -62.911 1.00 90.83 ? 160 LYS B CB 1 ATOM 5545 C CG . LYS B 2 149 ? -55.478 -41.761 -61.687 1.00 95.60 ? 160 LYS B CG 1 ATOM 5546 C CD . LYS B 2 149 ? -55.722 -40.608 -60.716 1.00 97.51 ? 160 LYS B CD 1 ATOM 5547 C CE . LYS B 2 149 ? -54.778 -40.661 -59.517 1.00 81.57 ? 160 LYS B CE 1 ATOM 5548 N NZ . LYS B 2 149 ? -55.157 -39.668 -58.466 1.00 67.79 ? 160 LYS B NZ 1 ATOM 5549 N N . GLU B 2 150 ? -53.805 -39.795 -63.666 1.00 66.05 ? 161 GLU B N 1 ATOM 5550 C CA . GLU B 2 150 ? -52.382 -39.829 -63.993 1.00 72.28 ? 161 GLU B CA 1 ATOM 5551 C C . GLU B 2 150 ? -51.537 -40.368 -62.841 1.00 67.91 ? 161 GLU B C 1 ATOM 5552 O O . GLU B 2 150 ? -51.182 -39.633 -61.917 1.00 71.16 ? 161 GLU B O 1 ATOM 5553 C CB . GLU B 2 150 ? -51.882 -38.438 -64.392 1.00 86.21 ? 161 GLU B CB 1 ATOM 5554 C CG . GLU B 2 150 ? -50.396 -38.402 -64.737 1.00 93.88 ? 161 GLU B CG 1 ATOM 5555 C CD . GLU B 2 150 ? -49.977 -37.118 -65.428 1.00 100.34 ? 161 GLU B CD 1 ATOM 5556 O OE1 . GLU B 2 150 ? -49.611 -37.180 -66.622 1.00 97.97 ? 161 GLU B OE1 1 ATOM 5557 O OE2 . GLU B 2 150 ? -50.015 -36.050 -64.781 1.00 96.00 ? 161 GLU B OE2 1 ATOM 5558 N N . ILE B 2 151 ? -51.222 -41.658 -62.902 1.00 66.96 ? 162 ILE B N 1 ATOM 5559 C CA . ILE B 2 151 ? -50.255 -42.255 -61.990 1.00 73.65 ? 162 ILE B CA 1 ATOM 5560 C C . ILE B 2 151 ? -48.884 -41.643 -62.261 1.00 74.12 ? 162 ILE B C 1 ATOM 5561 O O . ILE B 2 151 ? -48.508 -41.422 -63.413 1.00 77.72 ? 162 ILE B O 1 ATOM 5562 C CB . ILE B 2 151 ? -50.186 -43.804 -62.140 1.00 73.17 ? 162 ILE B CB 1 ATOM 5563 C CG1 . ILE B 2 151 ? -51.486 -44.455 -61.658 1.00 70.59 ? 162 ILE B CG1 1 ATOM 5564 C CG2 . ILE B 2 151 ? -48.989 -44.385 -61.384 1.00 63.64 ? 162 ILE B CG2 1 ATOM 5565 C CD1 . ILE B 2 151 ? -51.777 -44.235 -60.190 1.00 77.97 ? 162 ILE B CD1 1 ATOM 5566 N N . SER B 2 152 ? -48.150 -41.339 -61.198 1.00 76.58 ? 163 SER B N 1 ATOM 5567 C CA . SER B 2 152 ? -46.792 -40.848 -61.338 1.00 83.53 ? 163 SER B CA 1 ATOM 5568 C C . SER B 2 152 ? -45.828 -41.880 -60.773 1.00 79.02 ? 163 SER B C 1 ATOM 5569 O O . SER B 2 152 ? -46.244 -42.905 -60.227 1.00 68.91 ? 163 SER B O 1 ATOM 5570 C CB . SER B 2 152 ? -46.618 -39.499 -60.628 1.00 91.65 ? 163 SER B CB 1 ATOM 5571 O OG . SER B 2 152 ? -45.449 -38.822 -61.067 1.00 95.02 ? 163 SER B OG 1 ATOM 5572 N N . CYS B 2 153 ? -44.539 -41.607 -60.933 1.00 85.18 ? 164 CYS B N 1 ATOM 5573 C CA . CYS B 2 153 ? -43.485 -42.358 -60.267 1.00 85.59 ? 164 CYS B CA 1 ATOM 5574 C C . CYS B 2 153 ? -42.649 -41.343 -59.507 1.00 95.33 ? 164 CYS B C 1 ATOM 5575 O O . CYS B 2 153 ? -41.869 -40.603 -60.106 1.00 98.09 ? 164 CYS B O 1 ATOM 5576 C CB . CYS B 2 153 ? -42.635 -43.139 -61.270 1.00 86.43 ? 164 CYS B CB 1 ATOM 5577 S SG . CYS B 2 153 ? -42.221 -44.828 -60.750 1.00 95.90 ? 164 CYS B SG 1 ATOM 5578 N N . ARG B 2 154 ? -42.822 -41.297 -58.190 1.00 108.26 ? 165 ARG B N 1 ATOM 5579 C CA . ARG B 2 154 ? -42.311 -40.181 -57.399 1.00 118.29 ? 165 ARG B CA 1 ATOM 5580 C C . ARG B 2 154 ? -41.072 -40.523 -56.569 1.00 114.55 ? 165 ARG B C 1 ATOM 5581 O O . ARG B 2 154 ? -40.674 -41.684 -56.471 1.00 104.17 ? 165 ARG B O 1 ATOM 5582 C CB . ARG B 2 154 ? -43.418 -39.644 -56.479 1.00 123.10 ? 165 ARG B CB 1 ATOM 5583 C CG . ARG B 2 154 ? -43.676 -40.478 -55.229 1.00 116.90 ? 165 ARG B CG 1 ATOM 5584 C CD . ARG B 2 154 ? -44.949 -40.031 -54.516 1.00 106.67 ? 165 ARG B CD 1 ATOM 5585 N NE . ARG B 2 154 ? -45.190 -38.597 -54.662 1.00 103.38 ? 165 ARG B NE 1 ATOM 5586 C CZ . ARG B 2 154 ? -46.264 -38.076 -55.247 1.00 107.53 ? 165 ARG B CZ 1 ATOM 5587 N NH1 . ARG B 2 154 ? -47.206 -38.871 -55.734 1.00 103.97 ? 165 ARG B NH1 1 ATOM 5588 N NH2 . ARG B 2 154 ? -46.399 -36.759 -55.338 1.00 114.02 ? 165 ARG B NH2 1 ATOM 5589 N N . ASP B 2 155 ? -40.476 -39.480 -55.989 1.00 115.23 ? 166 ASP B N 1 ATOM 5590 C CA . ASP B 2 155 ? -39.290 -39.569 -55.132 1.00 120.56 ? 166 ASP B CA 1 ATOM 5591 C C . ASP B 2 155 ? -38.040 -40.059 -55.870 1.00 122.20 ? 166 ASP B C 1 ATOM 5592 O O . ASP B 2 155 ? -37.041 -40.400 -55.238 1.00 131.53 ? 166 ASP B O 1 ATOM 5593 C CB . ASP B 2 155 ? -39.563 -40.477 -53.925 1.00 122.46 ? 166 ASP B CB 1 ATOM 5594 C CG . ASP B 2 155 ? -40.635 -39.925 -52.999 1.00 122.03 ? 166 ASP B CG 1 ATOM 5595 O OD1 . ASP B 2 155 ? -40.891 -38.703 -53.027 1.00 125.66 ? 166 ASP B OD1 1 ATOM 5596 O OD2 . ASP B 2 155 ? -41.222 -40.722 -52.235 1.00 122.97 ? 166 ASP B OD2 1 ATOM 5597 N N . ILE B 2 156 ? -38.088 -40.074 -57.199 1.00 117.40 ? 167 ILE B N 1 ATOM 5598 C CA . ILE B 2 156 ? -36.963 -40.548 -58.003 1.00 115.92 ? 167 ILE B CA 1 ATOM 5599 C C . ILE B 2 156 ? -35.909 -39.451 -58.200 1.00 115.50 ? 167 ILE B C 1 ATOM 5600 O O . ILE B 2 156 ? -34.710 -39.732 -58.190 1.00 111.88 ? 167 ILE B O 1 ATOM 5601 C CB . ILE B 2 156 ? -37.442 -41.075 -59.385 1.00 113.48 ? 167 ILE B CB 1 ATOM 5602 C CG1 . ILE B 2 156 ? -38.354 -42.297 -59.210 1.00 111.20 ? 167 ILE B CG1 1 ATOM 5603 C CG2 . ILE B 2 156 ? -36.261 -41.430 -60.278 1.00 108.20 ? 167 ILE B CG2 1 ATOM 5604 C CD1 . ILE B 2 156 ? -38.842 -42.912 -60.522 1.00 109.31 ? 167 ILE B CD1 1 ATOM 5605 N N . GLU B 2 157 ? -36.378 -38.210 -58.345 1.00 114.91 ? 168 GLU B N 1 ATOM 5606 C CA . GLU B 2 157 ? -35.573 -37.000 -58.607 1.00 112.33 ? 168 GLU B CA 1 ATOM 5607 C C . GLU B 2 157 ? -34.042 -37.077 -58.452 1.00 107.99 ? 168 GLU B C 1 ATOM 5608 O O . GLU B 2 157 ? -33.309 -36.394 -59.169 1.00 108.65 ? 168 GLU B O 1 ATOM 5609 C CB . GLU B 2 157 ? -36.086 -35.866 -57.713 1.00 121.19 ? 168 GLU B CB 1 ATOM 5610 C CG . GLU B 2 157 ? -37.513 -35.434 -58.010 1.00 122.47 ? 168 GLU B CG 1 ATOM 5611 C CD . GLU B 2 157 ? -38.022 -34.398 -57.025 1.00 126.94 ? 168 GLU B CD 1 ATOM 5612 O OE1 . GLU B 2 157 ? -37.361 -34.191 -55.986 1.00 121.57 ? 168 GLU B OE1 1 ATOM 5613 O OE2 . GLU B 2 157 ? -39.081 -33.789 -57.290 1.00 138.62 ? 168 GLU B OE2 1 ATOM 5614 N N . ASP B 2 158 ? -33.570 -37.892 -57.513 1.00 108.62 ? 169 ASP B N 1 ATOM 5615 C CA . ASP B 2 158 ? -32.139 -38.081 -57.282 1.00 112.09 ? 169 ASP B CA 1 ATOM 5616 C C . ASP B 2 158 ? -31.454 -38.949 -58.344 1.00 116.77 ? 169 ASP B C 1 ATOM 5617 O O . ASP B 2 158 ? -30.234 -38.898 -58.497 1.00 124.19 ? 169 ASP B O 1 ATOM 5618 C CB . ASP B 2 158 ? -31.909 -38.702 -55.900 1.00 120.73 ? 169 ASP B CB 1 ATOM 5619 C CG . ASP B 2 158 ? -31.419 -37.693 -54.881 1.00 135.67 ? 169 ASP B CG 1 ATOM 5620 O OD1 . ASP B 2 158 ? -30.872 -36.654 -55.302 1.00 144.70 ? 169 ASP B OD1 1 ATOM 5621 O OD2 . ASP B 2 158 ? -31.572 -37.940 -53.665 1.00 132.98 ? 169 ASP B OD2 1 ATOM 5622 N N . PHE B 2 159 ? -32.238 -39.742 -59.069 1.00 116.00 ? 170 PHE B N 1 ATOM 5623 C CA . PHE B 2 159 ? -31.702 -40.671 -60.068 1.00 119.80 ? 170 PHE B CA 1 ATOM 5624 C C . PHE B 2 159 ? -31.798 -40.124 -61.501 1.00 118.87 ? 170 PHE B C 1 ATOM 5625 O O . PHE B 2 159 ? -31.255 -40.712 -62.441 1.00 110.53 ? 170 PHE B O 1 ATOM 5626 C CB . PHE B 2 159 ? -32.434 -42.012 -59.972 1.00 119.02 ? 170 PHE B CB 1 ATOM 5627 C CG . PHE B 2 159 ? -32.234 -42.721 -58.662 1.00 106.50 ? 170 PHE B CG 1 ATOM 5628 C CD1 . PHE B 2 159 ? -30.961 -42.922 -58.160 1.00 107.75 ? 170 PHE B CD1 1 ATOM 5629 C CD2 . PHE B 2 159 ? -33.317 -43.178 -57.929 1.00 101.59 ? 170 PHE B CD2 1 ATOM 5630 C CE1 . PHE B 2 159 ? -30.768 -43.573 -56.962 1.00 109.18 ? 170 PHE B CE1 1 ATOM 5631 C CE2 . PHE B 2 159 ? -33.132 -43.829 -56.727 1.00 112.31 ? 170 PHE B CE2 1 ATOM 5632 C CZ . PHE B 2 159 ? -31.854 -44.026 -56.243 1.00 111.75 ? 170 PHE B CZ 1 ATOM 5633 N N . LEU B 2 160 ? -32.489 -38.996 -61.647 1.00 121.58 ? 171 LEU B N 1 ATOM 5634 C CA . LEU B 2 160 ? -32.736 -38.353 -62.938 1.00 114.51 ? 171 LEU B CA 1 ATOM 5635 C C . LEU B 2 160 ? -31.483 -38.227 -63.808 1.00 107.11 ? 171 LEU B C 1 ATOM 5636 O O . LEU B 2 160 ? -30.375 -38.037 -63.306 1.00 86.68 ? 171 LEU B O 1 ATOM 5637 C CB . LEU B 2 160 ? -33.350 -36.966 -62.707 1.00 128.76 ? 171 LEU B CB 1 ATOM 5638 C CG . LEU B 2 160 ? -34.208 -36.322 -63.804 1.00 131.19 ? 171 LEU B CG 1 ATOM 5639 C CD1 . LEU B 2 160 ? -35.151 -35.287 -63.204 1.00 129.68 ? 171 LEU B CD1 1 ATOM 5640 C CD2 . LEU B 2 160 ? -33.358 -35.701 -64.905 1.00 124.63 ? 171 LEU B CD2 1 ATOM 5641 N N . GLU B 2 165 ? -35.059 -38.978 -68.166 1.00 205.08 ? 176 GLU B N 1 ATOM 5642 C CA . GLU B 2 165 ? -35.969 -39.691 -69.059 1.00 205.08 ? 176 GLU B CA 1 ATOM 5643 C C . GLU B 2 165 ? -35.573 -41.143 -69.361 1.00 205.08 ? 176 GLU B C 1 ATOM 5644 O O . GLU B 2 165 ? -35.689 -41.581 -70.504 1.00 205.08 ? 176 GLU B O 1 ATOM 5645 C CB . GLU B 2 165 ? -36.079 -38.925 -70.375 1.00 205.08 ? 176 GLU B CB 1 ATOM 5646 C CG . GLU B 2 165 ? -35.495 -37.523 -70.297 1.00 205.08 ? 176 GLU B CG 1 ATOM 5647 C CD . GLU B 2 165 ? -35.598 -36.766 -71.603 1.00 205.08 ? 176 GLU B CD 1 ATOM 5648 O OE1 . GLU B 2 165 ? -34.853 -37.100 -72.547 1.00 212.03 ? 176 GLU B OE1 1 ATOM 5649 O OE2 . GLU B 2 165 ? -36.425 -35.833 -71.684 1.00 205.08 ? 176 GLU B OE2 1 ATOM 5650 N N . PRO B 2 166 ? -35.115 -41.904 -68.349 1.00 174.08 ? 177 PRO B N 1 ATOM 5651 C CA . PRO B 2 166 ? -34.746 -43.278 -68.706 1.00 162.53 ? 177 PRO B CA 1 ATOM 5652 C C . PRO B 2 166 ? -35.973 -44.169 -68.893 1.00 152.47 ? 177 PRO B C 1 ATOM 5653 O O . PRO B 2 166 ? -37.099 -43.696 -68.745 1.00 145.94 ? 177 PRO B O 1 ATOM 5654 C CB . PRO B 2 166 ? -33.905 -43.732 -67.514 1.00 162.30 ? 177 PRO B CB 1 ATOM 5655 C CG . PRO B 2 166 ? -34.425 -42.942 -66.376 1.00 168.01 ? 177 PRO B CG 1 ATOM 5656 C CD . PRO B 2 166 ? -34.954 -41.648 -66.905 1.00 173.24 ? 177 PRO B CD 1 ATOM 5657 N N . GLU B 2 167 ? -35.754 -45.440 -69.216 1.00 151.36 ? 178 GLU B N 1 ATOM 5658 C CA . GLU B 2 167 ? -36.853 -46.360 -69.497 1.00 143.62 ? 178 GLU B CA 1 ATOM 5659 C C . GLU B 2 167 ? -37.603 -46.797 -68.237 1.00 122.33 ? 178 GLU B C 1 ATOM 5660 O O . GLU B 2 167 ? -37.005 -47.293 -67.282 1.00 124.92 ? 178 GLU B O 1 ATOM 5661 C CB . GLU B 2 167 ? -36.332 -47.593 -70.252 1.00 154.31 ? 178 GLU B CB 1 ATOM 5662 C CG . GLU B 2 167 ? -34.854 -47.908 -70.024 1.00 160.66 ? 178 GLU B CG 1 ATOM 5663 C CD . GLU B 2 167 ? -34.547 -48.312 -68.593 1.00 151.84 ? 178 GLU B CD 1 ATOM 5664 O OE1 . GLU B 2 167 ? -34.095 -47.446 -67.814 1.00 140.27 ? 178 GLU B OE1 1 ATOM 5665 O OE2 . GLU B 2 167 ? -34.760 -49.494 -68.249 1.00 154.07 ? 178 GLU B OE2 1 ATOM 5666 N N . ILE B 2 168 ? -38.919 -46.602 -68.240 1.00 105.16 ? 179 ILE B N 1 ATOM 5667 C CA . ILE B 2 168 ? -39.775 -47.094 -67.165 1.00 91.78 ? 179 ILE B CA 1 ATOM 5668 C C . ILE B 2 168 ? -40.555 -48.314 -67.650 1.00 96.44 ? 179 ILE B C 1 ATOM 5669 O O . ILE B 2 168 ? -41.280 -48.247 -68.645 1.00 106.73 ? 179 ILE B O 1 ATOM 5670 C CB . ILE B 2 168 ? -40.770 -46.013 -66.660 1.00 85.93 ? 179 ILE B CB 1 ATOM 5671 C CG1 . ILE B 2 168 ? -40.027 -44.792 -66.103 1.00 80.80 ? 179 ILE B CG1 1 ATOM 5672 C CG2 . ILE B 2 168 ? -41.685 -46.580 -65.583 1.00 87.04 ? 179 ILE B CG2 1 ATOM 5673 C CD1 . ILE B 2 168 ? -39.803 -43.687 -67.107 1.00 80.27 ? 179 ILE B CD1 1 ATOM 5674 N N . LEU B 2 169 ? -40.389 -49.433 -66.954 1.00 90.62 ? 180 LEU B N 1 ATOM 5675 C CA . LEU B 2 169 ? -41.152 -50.638 -67.253 1.00 89.78 ? 180 LEU B CA 1 ATOM 5676 C C . LEU B 2 169 ? -42.268 -50.834 -66.232 1.00 83.35 ? 180 LEU B C 1 ATOM 5677 O O . LEU B 2 169 ? -42.043 -51.354 -65.137 1.00 86.21 ? 180 LEU B O 1 ATOM 5678 C CB . LEU B 2 169 ? -40.239 -51.868 -67.290 1.00 97.59 ? 180 LEU B CB 1 ATOM 5679 C CG . LEU B 2 169 ? -39.582 -52.181 -68.638 1.00 109.19 ? 180 LEU B CG 1 ATOM 5680 C CD1 . LEU B 2 169 ? -40.626 -52.168 -69.748 1.00 106.66 ? 180 LEU B CD1 1 ATOM 5681 C CD2 . LEU B 2 169 ? -38.442 -51.219 -68.945 1.00 113.81 ? 180 LEU B CD2 1 ATOM 5682 N N . TRP B 2 170 ? -43.471 -50.400 -66.595 1.00 75.70 ? 181 TRP B N 1 ATOM 5683 C CA . TRP B 2 170 ? -44.638 -50.568 -65.741 1.00 70.07 ? 181 TRP B CA 1 ATOM 5684 C C . TRP B 2 170 ? -45.112 -52.014 -65.744 1.00 70.29 ? 181 TRP B C 1 ATOM 5685 O O . TRP B 2 170 ? -45.298 -52.617 -66.800 1.00 76.01 ? 181 TRP B O 1 ATOM 5686 C CB . TRP B 2 170 ? -45.773 -49.638 -66.185 1.00 72.82 ? 181 TRP B CB 1 ATOM 5687 C CG . TRP B 2 170 ? -45.515 -48.193 -65.884 1.00 77.54 ? 181 TRP B CG 1 ATOM 5688 C CD1 . TRP B 2 170 ? -45.016 -47.251 -66.739 1.00 85.95 ? 181 TRP B CD1 1 ATOM 5689 C CD2 . TRP B 2 170 ? -45.726 -47.528 -64.633 1.00 79.62 ? 181 TRP B CD2 1 ATOM 5690 N NE1 . TRP B 2 170 ? -44.915 -46.041 -66.102 1.00 83.52 ? 181 TRP B NE1 1 ATOM 5691 C CE2 . TRP B 2 170 ? -45.344 -46.182 -64.808 1.00 81.84 ? 181 TRP B CE2 1 ATOM 5692 C CE3 . TRP B 2 170 ? -46.214 -47.937 -63.385 1.00 83.30 ? 181 TRP B CE3 1 ATOM 5693 C CZ2 . TRP B 2 170 ? -45.428 -45.240 -63.784 1.00 85.05 ? 181 TRP B CZ2 1 ATOM 5694 C CZ3 . TRP B 2 170 ? -46.297 -47.000 -62.367 1.00 86.63 ? 181 TRP B CZ3 1 ATOM 5695 C CH2 . TRP B 2 170 ? -45.904 -45.667 -62.575 1.00 85.70 ? 181 TRP B CH2 1 ATOM 5696 N N . TYR B 2 171 ? -45.286 -52.569 -64.550 1.00 72.53 ? 182 TYR B N 1 ATOM 5697 C CA . TYR B 2 171 ? -45.886 -53.885 -64.402 1.00 74.31 ? 182 TYR B CA 1 ATOM 5698 C C . TYR B 2 171 ? -47.267 -53.754 -63.776 1.00 73.22 ? 182 TYR B C 1 ATOM 5699 O O . TYR B 2 171 ? -47.615 -52.718 -63.205 1.00 72.56 ? 182 TYR B O 1 ATOM 5700 C CB . TYR B 2 171 ? -45.016 -54.805 -63.537 1.00 81.50 ? 182 TYR B CB 1 ATOM 5701 C CG . TYR B 2 171 ? -43.546 -54.820 -63.887 1.00 83.27 ? 182 TYR B CG 1 ATOM 5702 C CD1 . TYR B 2 171 ? -43.124 -54.852 -65.209 1.00 81.80 ? 182 TYR B CD1 1 ATOM 5703 C CD2 . TYR B 2 171 ? -42.578 -54.799 -62.888 1.00 87.13 ? 182 TYR B CD2 1 ATOM 5704 C CE1 . TYR B 2 171 ? -41.778 -54.865 -65.528 1.00 87.62 ? 182 TYR B CE1 1 ATOM 5705 C CE2 . TYR B 2 171 ? -41.231 -54.810 -63.196 1.00 83.34 ? 182 TYR B CE2 1 ATOM 5706 C CZ . TYR B 2 171 ? -40.837 -54.844 -64.517 1.00 87.59 ? 182 TYR B CZ 1 ATOM 5707 O OH . TYR B 2 171 ? -39.499 -54.857 -64.832 1.00 98.95 ? 182 TYR B OH 1 ATOM 5708 N N . LYS B 2 172 ? -48.046 -54.821 -63.892 1.00 74.85 ? 183 LYS B N 1 ATOM 5709 C CA . LYS B 2 172 ? -49.336 -54.935 -63.231 1.00 76.36 ? 183 LYS B CA 1 ATOM 5710 C C . LYS B 2 172 ? -49.339 -56.237 -62.443 1.00 86.35 ? 183 LYS B C 1 ATOM 5711 O O . LYS B 2 172 ? -49.196 -57.314 -63.025 1.00 89.13 ? 183 LYS B O 1 ATOM 5712 C CB . LYS B 2 172 ? -50.474 -54.907 -64.250 1.00 72.13 ? 183 LYS B CB 1 ATOM 5713 C CG . LYS B 2 172 ? -51.847 -55.191 -63.673 1.00 67.54 ? 183 LYS B CG 1 ATOM 5714 C CD . LYS B 2 172 ? -52.564 -53.911 -63.309 1.00 61.13 ? 183 LYS B CD 1 ATOM 5715 C CE . LYS B 2 172 ? -54.055 -54.039 -63.565 1.00 63.12 ? 183 LYS B CE 1 ATOM 5716 N NZ . LYS B 2 172 ? -54.610 -55.270 -62.935 1.00 64.37 ? 183 LYS B NZ 1 ATOM 5717 N N . GLU B 2 173 ? -49.485 -56.131 -61.124 1.00 89.35 ? 184 GLU B N 1 ATOM 5718 C CA . GLU B 2 173 ? -49.393 -57.281 -60.225 1.00 88.94 ? 184 GLU B CA 1 ATOM 5719 C C . GLU B 2 173 ? -48.060 -58.006 -60.420 1.00 88.11 ? 184 GLU B C 1 ATOM 5720 O O . GLU B 2 173 ? -47.990 -59.234 -60.347 1.00 93.82 ? 184 GLU B O 1 ATOM 5721 C CB . GLU B 2 173 ? -50.568 -58.240 -60.441 1.00 88.70 ? 184 GLU B CB 1 ATOM 5722 C CG . GLU B 2 173 ? -51.933 -57.619 -60.188 1.00 87.85 ? 184 GLU B CG 1 ATOM 5723 C CD . GLU B 2 173 ? -52.066 -57.048 -58.788 1.00 96.07 ? 184 GLU B CD 1 ATOM 5724 O OE1 . GLU B 2 173 ? -51.531 -57.660 -57.836 1.00 102.50 ? 184 GLU B OE1 1 ATOM 5725 O OE2 . GLU B 2 173 ? -52.701 -55.981 -58.640 1.00 94.50 ? 184 GLU B OE2 1 ATOM 5726 N N . CYS B 2 174 ? -47.017 -57.219 -60.679 1.00 85.06 ? 185 CYS B N 1 ATOM 5727 C CA . CYS B 2 174 ? -45.649 -57.702 -60.882 1.00 92.69 ? 185 CYS B CA 1 ATOM 5728 C C . CYS B 2 174 ? -45.487 -58.630 -62.086 1.00 96.80 ? 185 CYS B C 1 ATOM 5729 O O . CYS B 2 174 ? -44.725 -59.596 -62.035 1.00 101.92 ? 185 CYS B O 1 ATOM 5730 C CB . CYS B 2 174 ? -45.144 -58.405 -59.620 1.00 96.26 ? 185 CYS B CB 1 ATOM 5731 S SG . CYS B 2 174 ? -45.120 -57.344 -58.161 1.00 107.60 ? 185 CYS B SG 1 ATOM 5732 N N . ARG B 2 175 ? -46.196 -58.326 -63.169 1.00 90.05 ? 186 ARG B N 1 ATOM 5733 C CA . ARG B 2 175 ? -46.050 -59.066 -64.420 1.00 91.54 ? 186 ARG B CA 1 ATOM 5734 C C . ARG B 2 175 ? -46.150 -58.131 -65.624 1.00 87.96 ? 186 ARG B C 1 ATOM 5735 O O . ARG B 2 175 ? -47.131 -57.397 -65.760 1.00 88.31 ? 186 ARG B O 1 ATOM 5736 C CB . ARG B 2 175 ? -47.111 -60.171 -64.527 1.00 95.94 ? 186 ARG B CB 1 ATOM 5737 C CG . ARG B 2 175 ? -47.034 -61.244 -63.447 1.00 108.34 ? 186 ARG B CG 1 ATOM 5738 C CD . ARG B 2 175 ? -48.052 -62.347 -63.692 1.00 128.05 ? 186 ARG B CD 1 ATOM 5739 N NE . ARG B 2 175 ? -47.729 -63.145 -64.872 1.00 146.34 ? 186 ARG B NE 1 ATOM 5740 C CZ . ARG B 2 175 ? -48.456 -64.170 -65.308 1.00 152.69 ? 186 ARG B CZ 1 ATOM 5741 N NH1 . ARG B 2 175 ? -49.558 -64.527 -64.664 1.00 163.06 ? 186 ARG B NH1 1 ATOM 5742 N NH2 . ARG B 2 175 ? -48.081 -64.839 -66.391 1.00 137.09 ? 186 ARG B NH2 1 ATOM 5743 N N . THR B 2 176 ? -45.135 -58.158 -66.487 1.00 88.35 ? 187 THR B N 1 ATOM 5744 C CA . THR B 2 176 ? -45.129 -57.356 -67.710 1.00 82.86 ? 187 THR B CA 1 ATOM 5745 C C . THR B 2 176 ? -46.316 -57.723 -68.590 1.00 72.78 ? 187 THR B C 1 ATOM 5746 O O . THR B 2 176 ? -46.529 -58.894 -68.909 1.00 75.70 ? 187 THR B O 1 ATOM 5747 C CB . THR B 2 176 ? -43.820 -57.543 -68.524 1.00 90.63 ? 187 THR B CB 1 ATOM 5748 O OG1 . THR B 2 176 ? -42.999 -58.540 -67.902 1.00 102.16 ? 187 THR B OG1 1 ATOM 5749 C CG2 . THR B 2 176 ? -43.039 -56.236 -68.612 1.00 85.99 ? 187 THR B CG2 1 ATOM 5750 N N . LYS B 2 177 ? -47.098 -56.720 -68.973 1.00 64.07 ? 188 LYS B N 1 ATOM 5751 C CA . LYS B 2 177 ? -48.305 -56.953 -69.757 1.00 69.74 ? 188 LYS B CA 1 ATOM 5752 C C . LYS B 2 177 ? -48.332 -56.088 -71.009 1.00 69.48 ? 188 LYS B C 1 ATOM 5753 O O . LYS B 2 177 ? -47.574 -55.121 -71.129 1.00 60.51 ? 188 LYS B O 1 ATOM 5754 C CB . LYS B 2 177 ? -49.560 -56.683 -68.913 1.00 73.41 ? 188 LYS B CB 1 ATOM 5755 C CG . LYS B 2 177 ? -49.998 -55.223 -68.882 1.00 76.11 ? 188 LYS B CG 1 ATOM 5756 C CD . LYS B 2 177 ? -51.258 -55.031 -68.047 1.00 76.29 ? 188 LYS B CD 1 ATOM 5757 C CE . LYS B 2 177 ? -52.446 -55.796 -68.615 1.00 77.00 ? 188 LYS B CE 1 ATOM 5758 N NZ . LYS B 2 177 ? -53.688 -55.516 -67.835 1.00 79.09 ? 188 LYS B NZ 1 ATOM 5759 N N . ALA B 2 178 ? -49.211 -56.455 -71.939 1.00 76.28 ? 189 ALA B N 1 ATOM 5760 C CA . ALA B 2 178 ? -49.477 -55.662 -73.133 1.00 75.75 ? 189 ALA B CA 1 ATOM 5761 C C . ALA B 2 178 ? -50.644 -54.721 -72.870 1.00 71.95 ? 189 ALA B C 1 ATOM 5762 O O . ALA B 2 178 ? -51.785 -55.160 -72.700 1.00 71.40 ? 189 ALA B O 1 ATOM 5763 C CB . ALA B 2 178 ? -49.775 -56.562 -74.324 1.00 86.34 ? 189 ALA B CB 1 ATOM 5764 N N . TRP B 2 179 ? -50.353 -53.425 -72.833 1.00 68.52 ? 190 TRP B N 1 ATOM 5765 C CA . TRP B 2 179 ? -51.343 -52.422 -72.452 1.00 73.86 ? 190 TRP B CA 1 ATOM 5766 C C . TRP B 2 179 ? -52.277 -52.036 -73.596 1.00 76.72 ? 190 TRP B C 1 ATOM 5767 O O . TRP B 2 179 ? -51.851 -51.883 -74.742 1.00 74.39 ? 190 TRP B O 1 ATOM 5768 C CB . TRP B 2 179 ? -50.643 -51.168 -71.909 1.00 81.52 ? 190 TRP B CB 1 ATOM 5769 C CG . TRP B 2 179 ? -49.832 -51.421 -70.669 1.00 76.99 ? 190 TRP B CG 1 ATOM 5770 C CD1 . TRP B 2 179 ? -48.490 -51.662 -70.601 1.00 82.62 ? 190 TRP B CD1 1 ATOM 5771 C CD2 . TRP B 2 179 ? -50.317 -51.468 -69.324 1.00 65.35 ? 190 TRP B CD2 1 ATOM 5772 N NE1 . TRP B 2 179 ? -48.109 -51.851 -69.297 1.00 77.46 ? 190 TRP B NE1 1 ATOM 5773 C CE2 . TRP B 2 179 ? -49.211 -51.737 -68.493 1.00 66.96 ? 190 TRP B CE2 1 ATOM 5774 C CE3 . TRP B 2 179 ? -51.578 -51.308 -68.742 1.00 67.68 ? 190 TRP B CE3 1 ATOM 5775 C CZ2 . TRP B 2 179 ? -49.326 -51.848 -67.113 1.00 72.31 ? 190 TRP B CZ2 1 ATOM 5776 C CZ3 . TRP B 2 179 ? -51.690 -51.416 -67.373 1.00 81.32 ? 190 TRP B CZ3 1 ATOM 5777 C CH2 . TRP B 2 179 ? -50.570 -51.685 -66.572 1.00 84.35 ? 190 TRP B CH2 1 ATOM 5778 N N . ARG B 2 180 ? -53.556 -51.875 -73.259 1.00 81.46 ? 191 ARG B N 1 ATOM 5779 C CA . ARG B 2 180 ? -54.596 -51.451 -74.197 1.00 84.62 ? 191 ARG B CA 1 ATOM 5780 C C . ARG B 2 180 ? -54.275 -50.049 -74.765 1.00 89.39 ? 191 ARG B C 1 ATOM 5781 O O . ARG B 2 180 ? -53.379 -49.372 -74.256 1.00 86.47 ? 191 ARG B O 1 ATOM 5782 C CB . ARG B 2 180 ? -55.963 -51.485 -73.495 1.00 86.25 ? 191 ARG B CB 1 ATOM 5783 C CG . ARG B 2 180 ? -56.239 -50.308 -72.582 1.00 94.18 ? 191 ARG B CG 1 ATOM 5784 C CD . ARG B 2 180 ? -57.729 -50.184 -72.328 1.00 101.14 ? 191 ARG B CD 1 ATOM 5785 N NE . ARG B 2 180 ? -58.047 -49.094 -71.411 1.00 98.42 ? 191 ARG B NE 1 ATOM 5786 C CZ . ARG B 2 180 ? -58.369 -49.261 -70.133 1.00 97.49 ? 191 ARG B CZ 1 ATOM 5787 N NH1 . ARG B 2 180 ? -58.427 -50.480 -69.615 1.00 85.38 ? 191 ARG B NH1 1 ATOM 5788 N NH2 . ARG B 2 180 ? -58.639 -48.206 -69.377 1.00 100.77 ? 191 ARG B NH2 1 ATOM 5789 N N . PRO B 2 181 ? -54.992 -49.605 -75.823 1.00 94.64 ? 192 PRO B N 1 ATOM 5790 C CA . PRO B 2 181 ? -54.504 -48.416 -76.540 1.00 92.46 ? 192 PRO B CA 1 ATOM 5791 C C . PRO B 2 181 ? -54.727 -47.063 -75.852 1.00 96.41 ? 192 PRO B C 1 ATOM 5792 O O . PRO B 2 181 ? -54.171 -46.068 -76.319 1.00 96.92 ? 192 PRO B O 1 ATOM 5793 C CB . PRO B 2 181 ? -55.299 -48.462 -77.847 1.00 94.72 ? 192 PRO B CB 1 ATOM 5794 C CG . PRO B 2 181 ? -56.587 -49.088 -77.453 1.00 99.48 ? 192 PRO B CG 1 ATOM 5795 C CD . PRO B 2 181 ? -56.216 -50.143 -76.451 1.00 99.36 ? 192 PRO B CD 1 ATOM 5796 N N . SER B 2 182 ? -55.506 -47.022 -74.774 1.00 93.92 ? 193 SER B N 1 ATOM 5797 C CA . SER B 2 182 ? -55.857 -45.753 -74.131 1.00 85.15 ? 193 SER B CA 1 ATOM 5798 C C . SER B 2 182 ? -54.812 -45.267 -73.123 1.00 82.85 ? 193 SER B C 1 ATOM 5799 O O . SER B 2 182 ? -55.103 -44.399 -72.296 1.00 83.76 ? 193 SER B O 1 ATOM 5800 C CB . SER B 2 182 ? -57.214 -45.874 -73.430 1.00 77.32 ? 193 SER B CB 1 ATOM 5801 O OG . SER B 2 182 ? -57.105 -46.599 -72.218 1.00 72.87 ? 193 SER B OG 1 ATOM 5802 N N . ILE B 2 183 ? -53.599 -45.810 -73.195 1.00 83.57 ? 194 ILE B N 1 ATOM 5803 C CA . ILE B 2 183 ? -52.590 -45.568 -72.161 1.00 70.23 ? 194 ILE B CA 1 ATOM 5804 C C . ILE B 2 183 ? -51.298 -44.936 -72.695 1.00 58.13 ? 194 ILE B C 1 ATOM 5805 O O . ILE B 2 183 ? -50.387 -45.629 -73.156 1.00 42.37 ? 194 ILE B O 1 ATOM 5806 C CB . ILE B 2 183 ? -52.251 -46.877 -71.428 1.00 57.54 ? 194 ILE B CB 1 ATOM 5807 C CG1 . ILE B 2 183 ? -53.549 -47.634 -71.102 1.00 62.72 ? 194 ILE B CG1 1 ATOM 5808 C CG2 . ILE B 2 183 ? -51.440 -46.593 -70.179 1.00 62.35 ? 194 ILE B CG2 1 ATOM 5809 C CD1 . ILE B 2 183 ? -53.384 -48.773 -70.139 1.00 68.19 ? 194 ILE B CD1 1 ATOM 5810 N N . VAL B 2 184 ? -51.231 -43.609 -72.609 1.00 67.88 ? 195 VAL B N 1 ATOM 5811 C CA . VAL B 2 184 ? -50.108 -42.828 -73.127 1.00 71.71 ? 195 VAL B CA 1 ATOM 5812 C C . VAL B 2 184 ? -48.954 -42.761 -72.127 1.00 61.79 ? 195 VAL B C 1 ATOM 5813 O O . VAL B 2 184 ? -48.998 -42.008 -71.152 1.00 72.79 ? 195 VAL B O 1 ATOM 5814 C CB . VAL B 2 184 ? -50.547 -41.379 -73.497 1.00 79.84 ? 195 VAL B CB 1 ATOM 5815 C CG1 . VAL B 2 184 ? -49.370 -40.565 -74.032 1.00 83.76 ? 195 VAL B CG1 1 ATOM 5816 C CG2 . VAL B 2 184 ? -51.689 -41.400 -74.507 1.00 75.59 ? 195 VAL B CG2 1 ATOM 5817 N N . PHE B 2 185 ? -47.927 -43.566 -72.375 1.00 48.60 ? 196 PHE B N 1 ATOM 5818 C CA . PHE B 2 185 ? -46.687 -43.505 -71.614 1.00 51.76 ? 196 PHE B CA 1 ATOM 5819 C C . PHE B 2 185 ? -45.885 -42.307 -72.089 1.00 60.49 ? 196 PHE B C 1 ATOM 5820 O O . PHE B 2 185 ? -45.608 -42.176 -73.281 1.00 75.38 ? 196 PHE B O 1 ATOM 5821 C CB . PHE B 2 185 ? -45.850 -44.782 -71.790 1.00 52.97 ? 196 PHE B CB 1 ATOM 5822 C CG . PHE B 2 185 ? -46.494 -46.033 -71.245 1.00 53.37 ? 196 PHE B CG 1 ATOM 5823 C CD1 . PHE B 2 185 ? -45.834 -46.814 -70.310 1.00 54.15 ? 196 PHE B CD1 1 ATOM 5824 C CD2 . PHE B 2 185 ? -47.743 -46.442 -71.683 1.00 52.51 ? 196 PHE B CD2 1 ATOM 5825 C CE1 . PHE B 2 185 ? -46.413 -47.973 -69.813 1.00 62.32 ? 196 PHE B CE1 1 ATOM 5826 C CE2 . PHE B 2 185 ? -48.328 -47.593 -71.191 1.00 59.56 ? 196 PHE B CE2 1 ATOM 5827 C CZ . PHE B 2 185 ? -47.665 -48.359 -70.253 1.00 64.92 ? 196 PHE B CZ 1 ATOM 5828 N N . LYS B 2 186 ? -45.522 -41.422 -71.170 1.00 64.04 ? 197 LYS B N 1 ATOM 5829 C CA . LYS B 2 186 ? -44.547 -40.391 -71.487 1.00 70.70 ? 197 LYS B CA 1 ATOM 5830 C C . LYS B 2 186 ? -43.255 -40.746 -70.779 1.00 77.00 ? 197 LYS B C 1 ATOM 5831 O O . LYS B 2 186 ? -42.798 -41.886 -70.858 1.00 79.94 ? 197 LYS B O 1 ATOM 5832 C CB . LYS B 2 186 ? -45.048 -39.001 -71.086 1.00 76.41 ? 197 LYS B CB 1 ATOM 5833 C CG . LYS B 2 186 ? -46.013 -38.412 -72.103 1.00 77.48 ? 197 LYS B CG 1 ATOM 5834 C CD . LYS B 2 186 ? -46.136 -36.906 -71.970 1.00 84.87 ? 197 LYS B CD 1 ATOM 5835 C CE . LYS B 2 186 ? -47.353 -36.522 -71.152 1.00 92.16 ? 197 LYS B CE 1 ATOM 5836 N NZ . LYS B 2 186 ? -47.470 -35.045 -71.028 1.00 111.65 ? 197 LYS B NZ 1 ATOM 5837 N N . ARG B 2 187 ? -42.668 -39.785 -70.080 1.00 83.41 ? 198 ARG B N 1 ATOM 5838 C CA . ARG B 2 187 ? -41.491 -40.083 -69.282 1.00 97.39 ? 198 ARG B CA 1 ATOM 5839 C C . ARG B 2 187 ? -41.902 -40.784 -67.988 1.00 96.37 ? 198 ARG B C 1 ATOM 5840 O O . ARG B 2 187 ? -42.245 -41.968 -67.996 1.00 92.11 ? 198 ARG B O 1 ATOM 5841 C CB . ARG B 2 187 ? -40.697 -38.809 -68.993 1.00 114.73 ? 198 ARG B CB 1 ATOM 5842 C CG . ARG B 2 187 ? -40.137 -38.157 -70.245 1.00 136.12 ? 198 ARG B CG 1 ATOM 5843 C CD . ARG B 2 187 ? -39.067 -37.135 -69.914 1.00 160.27 ? 198 ARG B CD 1 ATOM 5844 N NE . ARG B 2 187 ? -39.611 -35.977 -69.217 1.00 153.10 ? 198 ARG B NE 1 ATOM 5845 C CZ . ARG B 2 187 ? -40.026 -34.872 -69.826 1.00 159.26 ? 198 ARG B CZ 1 ATOM 5846 N NH1 . ARG B 2 187 ? -39.955 -34.777 -71.147 1.00 168.04 ? 198 ARG B NH1 1 ATOM 5847 N NH2 . ARG B 2 187 ? -40.510 -33.864 -69.115 1.00 164.91 ? 198 ARG B NH2 1 ATOM 5848 N N . ASP B 2 188 ? -41.894 -40.038 -66.887 1.00 101.45 ? 199 ASP B N 1 ATOM 5849 C CA . ASP B 2 188 ? -42.125 -40.597 -65.554 1.00 94.17 ? 199 ASP B CA 1 ATOM 5850 C C . ASP B 2 188 ? -43.590 -40.920 -65.244 1.00 89.13 ? 199 ASP B C 1 ATOM 5851 O O . ASP B 2 188 ? -43.907 -41.356 -64.136 1.00 100.65 ? 199 ASP B O 1 ATOM 5852 C CB . ASP B 2 188 ? -41.588 -39.632 -64.486 1.00 104.85 ? 199 ASP B CB 1 ATOM 5853 C CG . ASP B 2 188 ? -42.344 -38.305 -64.452 1.00 107.92 ? 199 ASP B CG 1 ATOM 5854 O OD1 . ASP B 2 188 ? -42.952 -37.928 -65.478 1.00 102.32 ? 199 ASP B OD1 1 ATOM 5855 O OD2 . ASP B 2 188 ? -42.326 -37.634 -63.395 1.00 109.14 ? 199 ASP B OD2 1 ATOM 5856 N N . THR B 2 189 ? -44.478 -40.709 -66.212 1.00 79.97 ? 200 THR B N 1 ATOM 5857 C CA . THR B 2 189 ? -45.913 -40.849 -65.964 1.00 78.53 ? 200 THR B CA 1 ATOM 5858 C C . THR B 2 189 ? -46.564 -41.977 -66.768 1.00 71.24 ? 200 THR B C 1 ATOM 5859 O O . THR B 2 189 ? -45.895 -42.717 -67.493 1.00 70.43 ? 200 THR B O 1 ATOM 5860 C CB . THR B 2 189 ? -46.671 -39.524 -66.276 1.00 78.30 ? 200 THR B CB 1 ATOM 5861 O OG1 . THR B 2 189 ? -46.519 -39.183 -67.663 1.00 78.91 ? 200 THR B OG1 1 ATOM 5862 C CG2 . THR B 2 189 ? -46.156 -38.380 -65.403 1.00 78.28 ? 200 THR B CG2 1 ATOM 5863 N N . LEU B 2 190 ? -47.875 -42.114 -66.595 1.00 64.86 ? 201 LEU B N 1 ATOM 5864 C CA . LEU B 2 190 ? -48.721 -42.910 -67.480 1.00 54.97 ? 201 LEU B CA 1 ATOM 5865 C C . LEU B 2 190 ? -50.158 -42.440 -67.273 1.00 51.55 ? 201 LEU B C 1 ATOM 5866 O O . LEU B 2 190 ? -50.596 -42.236 -66.143 1.00 62.82 ? 201 LEU B O 1 ATOM 5867 C CB . LEU B 2 190 ? -48.560 -44.421 -67.232 1.00 48.25 ? 201 LEU B CB 1 ATOM 5868 C CG . LEU B 2 190 ? -49.381 -45.271 -66.255 1.00 45.18 ? 201 LEU B CG 1 ATOM 5869 C CD1 . LEU B 2 190 ? -50.778 -45.573 -66.790 1.00 39.03 ? 201 LEU B CD1 1 ATOM 5870 C CD2 . LEU B 2 190 ? -48.649 -46.572 -65.983 1.00 51.18 ? 201 LEU B CD2 1 ATOM 5871 N N . LEU B 2 191 ? -50.889 -42.271 -68.367 1.00 52.58 ? 202 LEU B N 1 ATOM 5872 C CA . LEU B 2 191 ? -52.189 -41.613 -68.321 1.00 57.74 ? 202 LEU B CA 1 ATOM 5873 C C . LEU B 2 191 ? -53.298 -42.464 -68.931 1.00 62.50 ? 202 LEU B C 1 ATOM 5874 O O . LEU B 2 191 ? -53.374 -42.623 -70.148 1.00 71.14 ? 202 LEU B O 1 ATOM 5875 C CB . LEU B 2 191 ? -52.108 -40.259 -69.039 1.00 65.20 ? 202 LEU B CB 1 ATOM 5876 C CG . LEU B 2 191 ? -53.416 -39.535 -69.371 1.00 74.69 ? 202 LEU B CG 1 ATOM 5877 C CD1 . LEU B 2 191 ? -54.180 -39.168 -68.106 1.00 89.35 ? 202 LEU B CD1 1 ATOM 5878 C CD2 . LEU B 2 191 ? -53.156 -38.297 -70.219 1.00 82.89 ? 202 LEU B CD2 1 ATOM 5879 N N . ILE B 2 192 ? -54.156 -43.013 -68.076 1.00 62.96 ? 203 ILE B N 1 ATOM 5880 C CA . ILE B 2 192 ? -55.355 -43.706 -68.529 1.00 69.00 ? 203 ILE B CA 1 ATOM 5881 C C . ILE B 2 192 ? -56.437 -42.673 -68.832 1.00 71.32 ? 203 ILE B C 1 ATOM 5882 O O . ILE B 2 192 ? -57.023 -42.087 -67.922 1.00 76.35 ? 203 ILE B O 1 ATOM 5883 C CB . ILE B 2 192 ? -55.870 -44.721 -67.478 1.00 73.58 ? 203 ILE B CB 1 ATOM 5884 C CG1 . ILE B 2 192 ? -54.767 -45.717 -67.103 1.00 63.43 ? 203 ILE B CG1 1 ATOM 5885 C CG2 . ILE B 2 192 ? -57.102 -45.449 -67.995 1.00 80.87 ? 203 ILE B CG2 1 ATOM 5886 C CD1 . ILE B 2 192 ? -55.176 -46.733 -66.039 1.00 68.63 ? 203 ILE B CD1 1 ATOM 5887 N N . LYS B 2 193 ? -56.685 -42.444 -70.118 1.00 72.06 ? 204 LYS B N 1 ATOM 5888 C CA . LYS B 2 193 ? -57.634 -41.424 -70.558 1.00 80.51 ? 204 LYS B CA 1 ATOM 5889 C C . LYS B 2 193 ? -59.081 -41.764 -70.210 1.00 81.57 ? 204 LYS B C 1 ATOM 5890 O O . LYS B 2 193 ? -59.927 -40.874 -70.113 1.00 77.07 ? 204 LYS B O 1 ATOM 5891 C CB . LYS B 2 193 ? -57.513 -41.198 -72.069 1.00 96.51 ? 204 LYS B CB 1 ATOM 5892 C CG . LYS B 2 193 ? -56.446 -40.194 -72.470 1.00 105.19 ? 204 LYS B CG 1 ATOM 5893 C CD . LYS B 2 193 ? -56.651 -39.727 -73.906 1.00 113.03 ? 204 LYS B CD 1 ATOM 5894 C CE . LYS B 2 193 ? -56.521 -40.878 -74.895 1.00 97.30 ? 204 LYS B CE 1 ATOM 5895 N NZ . LYS B 2 193 ? -55.123 -41.383 -74.979 1.00 82.28 ? 204 LYS B NZ 1 ATOM 5896 N N . GLU B 2 194 ? -59.360 -43.053 -70.036 1.00 83.82 ? 205 GLU B N 1 ATOM 5897 C CA . GLU B 2 194 ? -60.690 -43.515 -69.641 1.00 88.20 ? 205 GLU B CA 1 ATOM 5898 C C . GLU B 2 194 ? -60.603 -44.742 -68.736 1.00 81.93 ? 205 GLU B C 1 ATOM 5899 O O . GLU B 2 194 ? -60.377 -45.856 -69.207 1.00 79.79 ? 205 GLU B O 1 ATOM 5900 C CB . GLU B 2 194 ? -61.542 -43.823 -70.874 1.00 96.20 ? 205 GLU B CB 1 ATOM 5901 C CG . GLU B 2 194 ? -62.274 -42.609 -71.437 1.00 103.33 ? 205 GLU B CG 1 ATOM 5902 C CD . GLU B 2 194 ? -63.781 -42.795 -71.450 1.00 109.68 ? 205 GLU B CD 1 ATOM 5903 O OE1 . GLU B 2 194 ? -64.231 -43.955 -71.353 1.00 115.85 ? 205 GLU B OE1 1 ATOM 5904 O OE2 . GLU B 2 194 ? -64.515 -41.788 -71.554 1.00 100.25 ? 205 GLU B OE2 1 ATOM 5905 N N . VAL B 2 195 ? -60.792 -44.529 -67.437 1.00 83.99 ? 206 VAL B N 1 ATOM 5906 C CA . VAL B 2 195 ? -60.560 -45.571 -66.441 1.00 86.70 ? 206 VAL B CA 1 ATOM 5907 C C . VAL B 2 195 ? -61.706 -46.583 -66.367 1.00 95.57 ? 206 VAL B C 1 ATOM 5908 O O . VAL B 2 195 ? -62.865 -46.219 -66.168 1.00 93.08 ? 206 VAL B O 1 ATOM 5909 C CB . VAL B 2 195 ? -60.319 -44.958 -65.030 1.00 89.60 ? 206 VAL B CB 1 ATOM 5910 C CG1 . VAL B 2 195 ? -60.354 -46.032 -63.949 1.00 94.82 ? 206 VAL B CG1 1 ATOM 5911 C CG2 . VAL B 2 195 ? -58.993 -44.205 -64.990 1.00 84.52 ? 206 VAL B CG2 1 ATOM 5912 N N . LYS B 2 196 ? -61.364 -47.857 -66.551 1.00 106.30 ? 207 LYS B N 1 ATOM 5913 C CA . LYS B 2 196 ? -62.302 -48.963 -66.372 1.00 111.50 ? 207 LYS B CA 1 ATOM 5914 C C . LYS B 2 196 ? -62.146 -49.568 -64.987 1.00 104.78 ? 207 LYS B C 1 ATOM 5915 O O . LYS B 2 196 ? -61.264 -49.175 -64.220 1.00 99.53 ? 207 LYS B O 1 ATOM 5916 C CB . LYS B 2 196 ? -62.092 -50.051 -67.431 1.00 115.74 ? 207 LYS B CB 1 ATOM 5917 C CG . LYS B 2 196 ? -62.656 -49.724 -68.800 1.00 124.14 ? 207 LYS B CG 1 ATOM 5918 C CD . LYS B 2 196 ? -62.481 -50.891 -69.762 1.00 113.09 ? 207 LYS B CD 1 ATOM 5919 C CE . LYS B 2 196 ? -62.906 -50.512 -71.174 1.00 121.78 ? 207 LYS B CE 1 ATOM 5920 N NZ . LYS B 2 196 ? -64.367 -50.238 -71.264 1.00 134.57 ? 207 LYS B NZ 1 ATOM 5921 N N . GLU B 2 197 ? -63.000 -50.534 -64.673 1.00 100.91 ? 208 GLU B N 1 ATOM 5922 C CA . GLU B 2 197 ? -62.949 -51.202 -63.381 1.00 102.56 ? 208 GLU B CA 1 ATOM 5923 C C . GLU B 2 197 ? -61.730 -52.122 -63.305 1.00 109.17 ? 208 GLU B C 1 ATOM 5924 O O . GLU B 2 197 ? -61.142 -52.302 -62.238 1.00 114.82 ? 208 GLU B O 1 ATOM 5925 C CB . GLU B 2 197 ? -64.237 -51.986 -63.141 1.00 102.02 ? 208 GLU B CB 1 ATOM 5926 C CG . GLU B 2 197 ? -64.524 -52.288 -61.685 1.00 109.11 ? 208 GLU B CG 1 ATOM 5927 C CD . GLU B 2 197 ? -65.901 -52.887 -61.487 1.00 122.66 ? 208 GLU B CD 1 ATOM 5928 O OE1 . GLU B 2 197 ? -66.256 -53.202 -60.332 1.00 115.99 ? 208 GLU B OE1 1 ATOM 5929 O OE2 . GLU B 2 197 ? -66.629 -53.041 -62.491 1.00 138.70 ? 208 GLU B OE2 1 ATOM 5930 N N . ASP B 2 198 ? -61.351 -52.682 -64.451 1.00 110.33 ? 209 ASP B N 1 ATOM 5931 C CA . ASP B 2 198 ? -60.171 -53.542 -64.572 1.00 109.13 ? 209 ASP B CA 1 ATOM 5932 C C . ASP B 2 198 ? -58.894 -52.855 -64.080 1.00 98.91 ? 209 ASP B C 1 ATOM 5933 O O . ASP B 2 198 ? -57.954 -53.512 -63.627 1.00 91.33 ? 209 ASP B O 1 ATOM 5934 C CB . ASP B 2 198 ? -60.001 -53.985 -66.033 1.00 127.80 ? 209 ASP B CB 1 ATOM 5935 C CG . ASP B 2 198 ? -58.715 -54.766 -66.274 1.00 137.88 ? 209 ASP B CG 1 ATOM 5936 O OD1 . ASP B 2 198 ? -58.317 -55.557 -65.394 1.00 136.80 ? 209 ASP B OD1 1 ATOM 5937 O OD2 . ASP B 2 198 ? -58.104 -54.589 -67.351 1.00 138.70 ? 209 ASP B OD2 1 ATOM 5938 N N . ASP B 2 199 ? -58.877 -51.527 -64.158 1.00 97.94 ? 210 ASP B N 1 ATOM 5939 C CA . ASP B 2 199 ? -57.701 -50.729 -63.818 1.00 96.81 ? 210 ASP B CA 1 ATOM 5940 C C . ASP B 2 199 ? -57.263 -50.860 -62.355 1.00 88.77 ? 210 ASP B C 1 ATOM 5941 O O . ASP B 2 199 ? -56.160 -50.444 -61.996 1.00 84.74 ? 210 ASP B O 1 ATOM 5942 C CB . ASP B 2 199 ? -57.962 -49.257 -64.141 1.00 98.37 ? 210 ASP B CB 1 ATOM 5943 C CG . ASP B 2 199 ? -58.285 -49.027 -65.607 1.00 103.16 ? 210 ASP B CG 1 ATOM 5944 O OD1 . ASP B 2 199 ? -58.214 -49.988 -66.402 1.00 113.30 ? 210 ASP B OD1 1 ATOM 5945 O OD2 . ASP B 2 199 ? -58.598 -47.878 -65.969 1.00 93.18 ? 210 ASP B OD2 1 ATOM 5946 N N . ILE B 2 200 ? -58.126 -51.428 -61.517 1.00 90.91 ? 211 ILE B N 1 ATOM 5947 C CA . ILE B 2 200 ? -57.793 -51.687 -60.120 1.00 89.59 ? 211 ILE B CA 1 ATOM 5948 C C . ILE B 2 200 ? -56.615 -52.646 -59.994 1.00 83.19 ? 211 ILE B C 1 ATOM 5949 O O . ILE B 2 200 ? -56.549 -53.654 -60.696 1.00 88.82 ? 211 ILE B O 1 ATOM 5950 C CB . ILE B 2 200 ? -59.001 -52.276 -59.351 1.00 94.62 ? 211 ILE B CB 1 ATOM 5951 C CG1 . ILE B 2 200 ? -60.102 -51.230 -59.202 1.00 96.45 ? 211 ILE B CG1 1 ATOM 5952 C CG2 . ILE B 2 200 ? -58.584 -52.789 -57.975 1.00 87.01 ? 211 ILE B CG2 1 ATOM 5953 C CD1 . ILE B 2 200 ? -61.331 -51.730 -58.465 1.00 94.39 ? 211 ILE B CD1 1 ATOM 5954 N N . GLY B 2 201 ? -55.683 -52.326 -59.103 1.00 74.50 ? 212 GLY B N 1 ATOM 5955 C CA . GLY B 2 201 ? -54.591 -53.230 -58.811 1.00 78.47 ? 212 GLY B CA 1 ATOM 5956 C C . GLY B 2 201 ? -53.304 -52.550 -58.403 1.00 75.89 ? 212 GLY B C 1 ATOM 5957 O O . GLY B 2 201 ? -53.282 -51.364 -58.065 1.00 70.48 ? 212 GLY B O 1 ATOM 5958 N N . ASN B 2 202 ? -52.222 -53.318 -58.448 1.00 78.13 ? 213 ASN B N 1 ATOM 5959 C CA . ASN B 2 202 ? -50.920 -52.855 -58.000 1.00 76.78 ? 213 ASN B CA 1 ATOM 5960 C C . ASN B 2 202 ? -49.980 -52.571 -59.158 1.00 77.91 ? 213 ASN B C 1 ATOM 5961 O O . ASN B 2 202 ? -49.370 -53.484 -59.719 1.00 81.29 ? 213 ASN B O 1 ATOM 5962 C CB . ASN B 2 202 ? -50.301 -53.886 -57.064 1.00 85.94 ? 213 ASN B CB 1 ATOM 5963 C CG . ASN B 2 202 ? -51.242 -54.284 -55.954 1.00 99.86 ? 213 ASN B CG 1 ATOM 5964 O OD1 . ASN B 2 202 ? -51.311 -53.613 -54.922 1.00 102.10 ? 213 ASN B OD1 1 ATOM 5965 N ND2 . ASN B 2 202 ? -52.004 -55.361 -56.176 1.00 105.65 ? 213 ASN B ND2 1 ATOM 5966 N N . TYR B 2 203 ? -49.876 -51.296 -59.515 1.00 75.45 ? 214 TYR B N 1 ATOM 5967 C CA . TYR B 2 203 ? -48.957 -50.867 -60.557 1.00 69.40 ? 214 TYR B CA 1 ATOM 5968 C C . TYR B 2 203 ? -47.578 -50.666 -59.944 1.00 73.67 ? 214 TYR B C 1 ATOM 5969 O O . TYR B 2 203 ? -47.360 -49.725 -59.180 1.00 78.18 ? 214 TYR B O 1 ATOM 5970 C CB . TYR B 2 203 ? -49.420 -49.566 -61.227 1.00 54.66 ? 214 TYR B CB 1 ATOM 5971 C CG . TYR B 2 203 ? -50.806 -49.574 -61.847 1.00 50.85 ? 214 TYR B CG 1 ATOM 5972 C CD1 . TYR B 2 203 ? -51.299 -48.436 -62.476 1.00 51.54 ? 214 TYR B CD1 1 ATOM 5973 C CD2 . TYR B 2 203 ? -51.619 -50.702 -61.806 1.00 60.99 ? 214 TYR B CD2 1 ATOM 5974 C CE1 . TYR B 2 203 ? -52.555 -48.422 -63.047 1.00 60.26 ? 214 TYR B CE1 1 ATOM 5975 C CE2 . TYR B 2 203 ? -52.884 -50.693 -62.369 1.00 65.33 ? 214 TYR B CE2 1 ATOM 5976 C CZ . TYR B 2 203 ? -53.344 -49.552 -62.990 1.00 65.60 ? 214 TYR B CZ 1 ATOM 5977 O OH . TYR B 2 203 ? -54.597 -49.545 -63.556 1.00 72.13 ? 214 TYR B OH 1 ATOM 5978 N N . THR B 2 204 ? -46.651 -51.561 -60.259 1.00 69.06 ? 215 THR B N 1 ATOM 5979 C CA . THR B 2 204 ? -45.270 -51.406 -59.826 1.00 66.35 ? 215 THR B CA 1 ATOM 5980 C C . THR B 2 204 ? -44.423 -50.973 -61.021 1.00 72.81 ? 215 THR B C 1 ATOM 5981 O O . THR B 2 204 ? -44.435 -51.623 -62.065 1.00 83.63 ? 215 THR B O 1 ATOM 5982 C CB . THR B 2 204 ? -44.712 -52.715 -59.201 1.00 64.13 ? 215 THR B CB 1 ATOM 5983 O OG1 . THR B 2 204 ? -43.283 -52.746 -59.315 1.00 60.78 ? 215 THR B OG1 1 ATOM 5984 C CG2 . THR B 2 204 ? -45.311 -53.941 -59.881 1.00 71.41 ? 215 THR B CG2 1 ATOM 5985 N N . CYS B 2 205 ? -43.715 -49.855 -60.883 1.00 70.51 ? 216 CYS B N 1 ATOM 5986 C CA . CYS B 2 205 ? -42.815 -49.407 -61.939 1.00 73.69 ? 216 CYS B CA 1 ATOM 5987 C C . CYS B 2 205 ? -41.376 -49.734 -61.578 1.00 81.36 ? 216 CYS B C 1 ATOM 5988 O O . CYS B 2 205 ? -41.034 -49.892 -60.404 1.00 77.80 ? 216 CYS B O 1 ATOM 5989 C CB . CYS B 2 205 ? -42.965 -47.907 -62.203 1.00 64.74 ? 216 CYS B CB 1 ATOM 5990 S SG . CYS B 2 205 ? -42.364 -46.850 -60.876 1.00 69.00 ? 216 CYS B SG 1 ATOM 5991 N N . GLU B 2 206 ? -40.534 -49.828 -62.599 1.00 87.33 ? 217 GLU B N 1 ATOM 5992 C CA . GLU B 2 206 ? -39.153 -50.230 -62.408 1.00 82.21 ? 217 GLU B CA 1 ATOM 5993 C C . GLU B 2 206 ? -38.191 -49.288 -63.121 1.00 83.78 ? 217 GLU B C 1 ATOM 5994 O O . GLU B 2 206 ? -38.532 -48.692 -64.143 1.00 86.78 ? 217 GLU B O 1 ATOM 5995 C CB . GLU B 2 206 ? -38.949 -51.662 -62.898 1.00 84.02 ? 217 GLU B CB 1 ATOM 5996 C CG . GLU B 2 206 ? -37.797 -52.358 -62.223 1.00 92.78 ? 217 GLU B CG 1 ATOM 5997 C CD . GLU B 2 206 ? -37.531 -53.731 -62.791 1.00 95.71 ? 217 GLU B CD 1 ATOM 5998 O OE1 . GLU B 2 206 ? -37.685 -53.897 -64.018 1.00 103.53 ? 217 GLU B OE1 1 ATOM 5999 O OE2 . GLU B 2 206 ? -37.179 -54.645 -62.014 1.00 92.50 ? 217 GLU B OE2 1 ATOM 6000 N N . LEU B 2 207 ? -36.985 -49.160 -62.574 1.00 88.53 ? 218 LEU B N 1 ATOM 6001 C CA . LEU B 2 207 ? -35.983 -48.248 -63.116 1.00 95.18 ? 218 LEU B CA 1 ATOM 6002 C C . LEU B 2 207 ? -34.556 -48.744 -62.857 1.00 105.08 ? 218 LEU B C 1 ATOM 6003 O O . LEU B 2 207 ? -34.278 -49.362 -61.827 1.00 105.76 ? 218 LEU B O 1 ATOM 6004 C CB . LEU B 2 207 ? -36.172 -46.845 -62.522 1.00 87.52 ? 218 LEU B CB 1 ATOM 6005 C CG . LEU B 2 207 ? -35.207 -45.755 -62.998 1.00 89.75 ? 218 LEU B CG 1 ATOM 6006 C CD1 . LEU B 2 207 ? -35.210 -45.709 -64.511 1.00 106.61 ? 218 LEU B CD1 1 ATOM 6007 C CD2 . LEU B 2 207 ? -35.555 -44.392 -62.414 1.00 103.23 ? 218 LEU B CD2 1 ATOM 6008 N N . LYS B 2 208 ? -33.660 -48.462 -63.801 1.00 107.43 ? 219 LYS B N 1 ATOM 6009 C CA . LYS B 2 208 ? -32.259 -48.863 -63.721 1.00 106.14 ? 219 LYS B CA 1 ATOM 6010 C C . LYS B 2 208 ? -31.352 -47.659 -63.428 1.00 99.48 ? 219 LYS B C 1 ATOM 6011 O O . LYS B 2 208 ? -31.610 -46.549 -63.901 1.00 94.94 ? 219 LYS B O 1 ATOM 6012 C CB . LYS B 2 208 ? -31.831 -49.548 -65.027 1.00 108.52 ? 219 LYS B CB 1 ATOM 6013 C CG . LYS B 2 208 ? -30.394 -50.051 -65.047 1.00 109.73 ? 219 LYS B CG 1 ATOM 6014 C CD . LYS B 2 208 ? -30.271 -51.463 -64.496 1.00 102.47 ? 219 LYS B CD 1 ATOM 6015 C CE . LYS B 2 208 ? -28.848 -51.738 -64.037 1.00 106.47 ? 219 LYS B CE 1 ATOM 6016 N NZ . LYS B 2 208 ? -27.877 -50.830 -64.712 1.00 110.06 ? 219 LYS B NZ 1 ATOM 6017 N N . TYR B 2 209 ? -30.301 -47.903 -62.645 1.00 93.85 ? 220 TYR B N 1 ATOM 6018 C CA . TYR B 2 209 ? -29.286 -46.914 -62.275 1.00 94.28 ? 220 TYR B CA 1 ATOM 6019 C C . TYR B 2 209 ? -28.272 -47.600 -61.363 1.00 98.03 ? 220 TYR B C 1 ATOM 6020 O O . TYR B 2 209 ? -28.641 -48.488 -60.599 1.00 93.30 ? 220 TYR B O 1 ATOM 6021 C CB . TYR B 2 209 ? -29.910 -45.701 -61.570 1.00 102.96 ? 220 TYR B CB 1 ATOM 6022 C CG . TYR B 2 209 ? -28.907 -44.686 -61.056 1.00 120.18 ? 220 TYR B CG 1 ATOM 6023 C CD1 . TYR B 2 209 ? -28.438 -43.663 -61.874 1.00 128.47 ? 220 TYR B CD1 1 ATOM 6024 C CD2 . TYR B 2 209 ? -28.434 -44.749 -59.750 1.00 116.98 ? 220 TYR B CD2 1 ATOM 6025 C CE1 . TYR B 2 209 ? -27.522 -42.735 -61.404 1.00 132.77 ? 220 TYR B CE1 1 ATOM 6026 C CE2 . TYR B 2 209 ? -27.520 -43.829 -59.273 1.00 115.93 ? 220 TYR B CE2 1 ATOM 6027 C CZ . TYR B 2 209 ? -27.067 -42.824 -60.102 1.00 128.59 ? 220 TYR B CZ 1 ATOM 6028 O OH . TYR B 2 209 ? -26.158 -41.909 -59.624 1.00 138.61 ? 220 TYR B OH 1 ATOM 6029 N N . GLY B 2 210 ? -27.002 -47.210 -61.440 1.00 112.11 ? 221 GLY B N 1 ATOM 6030 C CA . GLY B 2 210 ? -26.005 -47.765 -60.536 1.00 115.21 ? 221 GLY B CA 1 ATOM 6031 C C . GLY B 2 210 ? -24.755 -48.407 -61.120 1.00 114.52 ? 221 GLY B C 1 ATOM 6032 O O . GLY B 2 210 ? -23.663 -47.844 -61.011 1.00 111.36 ? 221 GLY B O 1 ATOM 6033 N N . GLY B 2 211 ? -24.898 -49.580 -61.738 1.00 107.04 ? 222 GLY B N 1 ATOM 6034 C CA . GLY B 2 211 ? -26.192 -50.186 -62.004 1.00 98.58 ? 222 GLY B CA 1 ATOM 6035 C C . GLY B 2 211 ? -26.837 -51.036 -60.922 1.00 97.54 ? 222 GLY B C 1 ATOM 6036 O O . GLY B 2 211 ? -26.211 -51.933 -60.355 1.00 102.10 ? 222 GLY B O 1 ATOM 6037 N N . PHE B 2 212 ? -28.105 -50.734 -60.648 1.00 91.70 ? 223 PHE B N 1 ATOM 6038 C CA . PHE B 2 212 ? -28.978 -51.551 -59.803 1.00 87.06 ? 223 PHE B CA 1 ATOM 6039 C C . PHE B 2 212 ? -30.417 -51.431 -60.294 1.00 81.87 ? 223 PHE B C 1 ATOM 6040 O O . PHE B 2 212 ? -30.660 -50.944 -61.396 1.00 89.25 ? 223 PHE B O 1 ATOM 6041 C CB . PHE B 2 212 ? -28.908 -51.126 -58.340 1.00 89.12 ? 223 PHE B CB 1 ATOM 6042 C CG . PHE B 2 212 ? -27.552 -51.260 -57.727 1.00 87.86 ? 223 PHE B CG 1 ATOM 6043 C CD1 . PHE B 2 212 ? -27.108 -52.484 -57.262 1.00 85.03 ? 223 PHE B CD1 1 ATOM 6044 C CD2 . PHE B 2 212 ? -26.726 -50.158 -57.603 1.00 91.12 ? 223 PHE B CD2 1 ATOM 6045 C CE1 . PHE B 2 212 ? -25.863 -52.607 -56.695 1.00 92.08 ? 223 PHE B CE1 1 ATOM 6046 C CE2 . PHE B 2 212 ? -25.480 -50.275 -57.037 1.00 92.66 ? 223 PHE B CE2 1 ATOM 6047 C CZ . PHE B 2 212 ? -25.046 -51.500 -56.581 1.00 96.50 ? 223 PHE B CZ 1 ATOM 6048 N N . VAL B 2 213 ? -31.372 -51.871 -59.478 1.00 70.15 ? 224 VAL B N 1 ATOM 6049 C CA . VAL B 2 213 ? -32.785 -51.760 -59.830 1.00 75.25 ? 224 VAL B CA 1 ATOM 6050 C C . VAL B 2 213 ? -33.601 -51.209 -58.660 1.00 81.25 ? 224 VAL B C 1 ATOM 6051 O O . VAL B 2 213 ? -33.535 -51.731 -57.548 1.00 89.99 ? 224 VAL B O 1 ATOM 6052 C CB . VAL B 2 213 ? -33.378 -53.123 -60.266 1.00 87.47 ? 224 VAL B CB 1 ATOM 6053 C CG1 . VAL B 2 213 ? -34.525 -52.907 -61.227 1.00 85.61 ? 224 VAL B CG1 1 ATOM 6054 C CG2 . VAL B 2 213 ? -32.322 -53.997 -60.923 1.00 104.36 ? 224 VAL B CG2 1 ATOM 6055 N N . VAL B 2 214 ? -34.362 -50.149 -58.923 1.00 81.21 ? 225 VAL B N 1 ATOM 6056 C CA . VAL B 2 214 ? -35.214 -49.515 -57.919 1.00 84.43 ? 225 VAL B CA 1 ATOM 6057 C C . VAL B 2 214 ? -36.684 -49.706 -58.293 1.00 82.83 ? 225 VAL B C 1 ATOM 6058 O O . VAL B 2 214 ? -37.039 -49.645 -59.470 1.00 88.33 ? 225 VAL B O 1 ATOM 6059 C CB . VAL B 2 214 ? -34.892 -47.999 -57.778 1.00 82.40 ? 225 VAL B CB 1 ATOM 6060 C CG1 . VAL B 2 214 ? -35.956 -47.271 -56.966 1.00 85.59 ? 225 VAL B CG1 1 ATOM 6061 C CG2 . VAL B 2 214 ? -33.524 -47.804 -57.153 1.00 84.54 ? 225 VAL B CG2 1 ATOM 6062 N N . ARG B 2 215 ? -37.532 -49.963 -57.299 1.00 77.87 ? 226 ARG B N 1 ATOM 6063 C CA . ARG B 2 215 ? -38.962 -50.114 -57.536 1.00 73.02 ? 226 ARG B CA 1 ATOM 6064 C C . ARG B 2 215 ? -39.785 -49.182 -56.657 1.00 72.16 ? 226 ARG B C 1 ATOM 6065 O O . ARG B 2 215 ? -39.488 -48.986 -55.477 1.00 81.14 ? 226 ARG B O 1 ATOM 6066 C CB . ARG B 2 215 ? -39.397 -51.563 -57.306 1.00 75.50 ? 226 ARG B CB 1 ATOM 6067 C CG . ARG B 2 215 ? -38.663 -52.559 -58.176 1.00 80.65 ? 226 ARG B CG 1 ATOM 6068 C CD . ARG B 2 215 ? -39.108 -53.975 -57.898 1.00 90.60 ? 226 ARG B CD 1 ATOM 6069 N NE . ARG B 2 215 ? -38.182 -54.941 -58.478 1.00 104.29 ? 226 ARG B NE 1 ATOM 6070 C CZ . ARG B 2 215 ? -37.061 -55.342 -57.889 1.00 104.04 ? 226 ARG B CZ 1 ATOM 6071 N NH1 . ARG B 2 215 ? -36.728 -54.860 -56.699 1.00 91.62 ? 226 ARG B NH1 1 ATOM 6072 N NH2 . ARG B 2 215 ? -36.272 -56.223 -58.490 1.00 109.38 ? 226 ARG B NH2 1 ATOM 6073 N N . ARG B 2 216 ? -40.815 -48.600 -57.261 1.00 67.57 ? 227 ARG B N 1 ATOM 6074 C CA . ARG B 2 216 ? -41.787 -47.770 -56.562 1.00 69.59 ? 227 ARG B CA 1 ATOM 6075 C C . ARG B 2 216 ? -43.180 -48.200 -57.004 1.00 70.79 ? 227 ARG B C 1 ATOM 6076 O O . ARG B 2 216 ? -43.550 -48.027 -58.164 1.00 77.52 ? 227 ARG B O 1 ATOM 6077 C CB . ARG B 2 216 ? -41.565 -46.285 -56.860 1.00 80.52 ? 227 ARG B CB 1 ATOM 6078 C CG . ARG B 2 216 ? -40.139 -45.797 -56.672 1.00 85.19 ? 227 ARG B CG 1 ATOM 6079 C CD . ARG B 2 216 ? -39.897 -45.252 -55.275 1.00 95.16 ? 227 ARG B CD 1 ATOM 6080 N NE . ARG B 2 216 ? -38.686 -44.438 -55.234 1.00 95.78 ? 227 ARG B NE 1 ATOM 6081 C CZ . ARG B 2 216 ? -37.520 -44.845 -54.746 1.00 97.25 ? 227 ARG B CZ 1 ATOM 6082 N NH1 . ARG B 2 216 ? -37.398 -46.060 -54.231 1.00 92.57 ? 227 ARG B NH1 1 ATOM 6083 N NH2 . ARG B 2 216 ? -36.476 -44.026 -54.764 1.00 104.60 ? 227 ARG B NH2 1 ATOM 6084 N N . THR B 2 217 ? -43.952 -48.771 -56.088 1.00 64.75 ? 228 THR B N 1 ATOM 6085 C CA . THR B 2 217 ? -45.224 -49.377 -56.459 1.00 64.77 ? 228 THR B CA 1 ATOM 6086 C C . THR B 2 217 ? -46.394 -48.653 -55.807 1.00 59.20 ? 228 THR B C 1 ATOM 6087 O O . THR B 2 217 ? -46.343 -48.303 -54.632 1.00 71.93 ? 228 THR B O 1 ATOM 6088 C CB . THR B 2 217 ? -45.240 -50.875 -56.087 1.00 72.16 ? 228 THR B CB 1 ATOM 6089 O OG1 . THR B 2 217 ? -45.912 -51.073 -54.837 1.00 71.53 ? 228 THR B OG1 1 ATOM 6090 C CG2 . THR B 2 217 ? -43.811 -51.389 -55.994 1.00 75.02 ? 228 THR B CG2 1 ATOM 6091 N N . THR B 2 218 ? -47.442 -48.407 -56.586 1.00 56.70 ? 229 THR B N 1 ATOM 6092 C CA . THR B 2 218 ? -48.624 -47.733 -56.070 1.00 60.62 ? 229 THR B CA 1 ATOM 6093 C C . THR B 2 218 ? -49.877 -48.558 -56.364 1.00 68.62 ? 229 THR B C 1 ATOM 6094 O O . THR B 2 218 ? -50.044 -49.097 -57.458 1.00 73.57 ? 229 THR B O 1 ATOM 6095 C CB . THR B 2 218 ? -48.771 -46.301 -56.658 1.00 59.51 ? 229 THR B CB 1 ATOM 6096 O OG1 . THR B 2 218 ? -49.995 -46.190 -57.394 1.00 63.99 ? 229 THR B OG1 1 ATOM 6097 C CG2 . THR B 2 218 ? -47.594 -45.961 -57.568 1.00 54.67 ? 229 THR B CG2 1 ATOM 6098 N N . GLU B 2 219 ? -50.748 -48.665 -55.366 1.00 74.11 ? 230 GLU B N 1 ATOM 6099 C CA . GLU B 2 219 ? -51.982 -49.431 -55.490 1.00 75.65 ? 230 GLU B CA 1 ATOM 6100 C C . GLU B 2 219 ? -53.120 -48.542 -55.977 1.00 72.03 ? 230 GLU B C 1 ATOM 6101 O O . GLU B 2 219 ? -53.369 -47.475 -55.417 1.00 69.54 ? 230 GLU B O 1 ATOM 6102 C CB . GLU B 2 219 ? -52.339 -50.079 -54.150 1.00 83.49 ? 230 GLU B CB 1 ATOM 6103 C CG . GLU B 2 219 ? -53.631 -50.862 -54.159 1.00 91.70 ? 230 GLU B CG 1 ATOM 6104 C CD . GLU B 2 219 ? -53.739 -51.800 -52.979 1.00 88.50 ? 230 GLU B CD 1 ATOM 6105 O OE1 . GLU B 2 219 ? -54.871 -52.045 -52.514 1.00 90.48 ? 230 GLU B OE1 1 ATOM 6106 O OE2 . GLU B 2 219 ? -52.690 -52.294 -52.518 1.00 79.51 ? 230 GLU B OE2 1 ATOM 6107 N N . LEU B 2 220 ? -53.804 -48.980 -57.030 1.00 75.40 ? 231 LEU B N 1 ATOM 6108 C CA . LEU B 2 220 ? -54.887 -48.195 -57.612 1.00 83.86 ? 231 LEU B CA 1 ATOM 6109 C C . LEU B 2 220 ? -56.258 -48.752 -57.240 1.00 88.12 ? 231 LEU B C 1 ATOM 6110 O O . LEU B 2 220 ? -56.594 -49.891 -57.571 1.00 87.64 ? 231 LEU B O 1 ATOM 6111 C CB . LEU B 2 220 ? -54.754 -48.130 -59.139 1.00 86.35 ? 231 LEU B CB 1 ATOM 6112 C CG . LEU B 2 220 ? -55.091 -46.813 -59.863 1.00 86.01 ? 231 LEU B CG 1 ATOM 6113 C CD1 . LEU B 2 220 ? -55.327 -47.043 -61.355 1.00 80.81 ? 231 LEU B CD1 1 ATOM 6114 C CD2 . LEU B 2 220 ? -56.275 -46.072 -59.247 1.00 89.93 ? 231 LEU B CD2 1 ATOM 6115 N N . THR B 2 221 ? -57.039 -47.929 -56.546 1.00 90.76 ? 232 THR B N 1 ATOM 6116 C CA . THR B 2 221 ? -58.440 -48.215 -56.272 1.00 91.12 ? 232 THR B CA 1 ATOM 6117 C C . THR B 2 221 ? -59.292 -47.232 -57.070 1.00 88.81 ? 232 THR B C 1 ATOM 6118 O O . THR B 2 221 ? -58.981 -46.043 -57.133 1.00 91.74 ? 232 THR B O 1 ATOM 6119 C CB . THR B 2 221 ? -58.768 -48.108 -54.763 1.00 95.88 ? 232 THR B CB 1 ATOM 6120 O OG1 . THR B 2 221 ? -58.606 -46.753 -54.322 1.00 94.29 ? 232 THR B OG1 1 ATOM 6121 C CG2 . THR B 2 221 ? -57.855 -49.022 -53.949 1.00 92.01 ? 232 THR B CG2 1 ATOM 6122 N N . VAL B 2 222 ? -60.351 -47.725 -57.703 1.00 84.26 ? 233 VAL B N 1 ATOM 6123 C CA . VAL B 2 222 ? -61.201 -46.855 -58.505 1.00 86.73 ? 233 VAL B CA 1 ATOM 6124 C C . VAL B 2 222 ? -62.591 -46.740 -57.884 1.00 95.62 ? 233 VAL B C 1 ATOM 6125 O O . VAL B 2 222 ? -63.039 -47.633 -57.163 1.00 105.50 ? 233 VAL B O 1 ATOM 6126 C CB . VAL B 2 222 ? -61.315 -47.348 -59.968 1.00 92.75 ? 233 VAL B CB 1 ATOM 6127 C CG1 . VAL B 2 222 ? -59.940 -47.684 -60.523 1.00 93.93 ? 233 VAL B CG1 1 ATOM 6128 C CG2 . VAL B 2 222 ? -62.251 -48.548 -60.076 1.00 99.79 ? 233 VAL B CG2 1 ATOM 6129 N N . THR B 2 223 ? -63.257 -45.621 -58.149 1.00 90.80 ? 234 THR B N 1 ATOM 6130 C CA . THR B 2 223 ? -64.598 -45.383 -57.630 1.00 87.89 ? 234 THR B CA 1 ATOM 6131 C C . THR B 2 223 ? -65.543 -44.975 -58.750 1.00 86.82 ? 234 THR B C 1 ATOM 6132 O O . THR B 2 223 ? -65.118 -44.742 -59.884 1.00 88.97 ? 234 THR B O 1 ATOM 6133 C CB . THR B 2 223 ? -64.615 -44.276 -56.539 1.00 90.03 ? 234 THR B CB 1 ATOM 6134 O OG1 . THR B 2 223 ? -64.121 -43.044 -57.082 1.00 88.77 ? 234 THR B OG1 1 ATOM 6135 C CG2 . THR B 2 223 ? -63.761 -44.675 -55.342 1.00 105.72 ? 234 THR B CG2 1 ATOM 6136 N N . ALA B 2 224 ? -66.829 -44.908 -58.423 1.00 88.88 ? 235 ALA B N 1 ATOM 6137 C CA . ALA B 2 224 ? -67.817 -44.265 -59.273 1.00 90.56 ? 235 ALA B CA 1 ATOM 6138 C C . ALA B 2 224 ? -67.440 -42.794 -59.426 1.00 83.61 ? 235 ALA B C 1 ATOM 6139 O O . ALA B 2 224 ? -66.669 -42.273 -58.622 1.00 82.83 ? 235 ALA B O 1 ATOM 6140 C CB . ALA B 2 224 ? -69.205 -44.409 -58.669 1.00 96.26 ? 235 ALA B CB 1 ATOM 6141 N N . PRO B 2 225 ? -67.976 -42.110 -60.451 1.00 81.54 ? 236 PRO B N 1 ATOM 6142 C CA . PRO B 2 225 ? -67.640 -40.685 -60.571 1.00 85.44 ? 236 PRO B CA 1 ATOM 6143 C C . PRO B 2 225 ? -68.195 -39.865 -59.412 1.00 86.24 ? 236 PRO B C 1 ATOM 6144 O O . PRO B 2 225 ? -68.945 -40.395 -58.592 1.00 87.77 ? 236 PRO B O 1 ATOM 6145 C CB . PRO B 2 225 ? -68.303 -40.278 -61.890 1.00 97.90 ? 236 PRO B CB 1 ATOM 6146 C CG . PRO B 2 225 ? -69.403 -41.270 -62.077 1.00 100.51 ? 236 PRO B CG 1 ATOM 6147 C CD . PRO B 2 225 ? -68.872 -42.558 -61.532 1.00 89.70 ? 236 PRO B CD 1 ATOM 6148 N N . LEU B 2 226 ? -67.831 -38.590 -59.341 1.00 90.79 ? 237 LEU B N 1 ATOM 6149 C CA . LEU B 2 226 ? -68.396 -37.703 -58.334 1.00 98.38 ? 237 LEU B CA 1 ATOM 6150 C C . LEU B 2 226 ? -69.893 -37.533 -58.540 1.00 101.83 ? 237 LEU B C 1 ATOM 6151 O O . LEU B 2 226 ? -70.328 -36.996 -59.558 1.00 108.09 ? 237 LEU B O 1 ATOM 6152 C CB . LEU B 2 226 ? -67.710 -36.335 -58.362 1.00 99.69 ? 237 LEU B CB 1 ATOM 6153 C CG . LEU B 2 226 ? -66.467 -36.186 -57.485 1.00 102.92 ? 237 LEU B CG 1 ATOM 6154 C CD1 . LEU B 2 226 ? -65.914 -34.773 -57.575 1.00 102.53 ? 237 LEU B CD1 1 ATOM 6155 C CD2 . LEU B 2 226 ? -66.788 -36.549 -56.043 1.00 102.11 ? 237 LEU B CD2 1 ATOM 6156 N N . THR B 2 227 ? -70.679 -38.000 -57.575 1.00 102.73 ? 238 THR B N 1 ATOM 6157 C CA . THR B 2 227 ? -72.118 -37.789 -57.607 1.00 102.95 ? 238 THR B CA 1 ATOM 6158 C C . THR B 2 227 ? -72.396 -36.292 -57.558 1.00 106.62 ? 238 THR B C 1 ATOM 6159 O O . THR B 2 227 ? -71.627 -35.522 -56.980 1.00 106.61 ? 238 THR B O 1 ATOM 6160 C CB . THR B 2 227 ? -72.844 -38.500 -56.441 1.00 103.44 ? 238 THR B CB 1 ATOM 6161 O OG1 . THR B 2 227 ? -74.262 -38.411 -56.630 1.00 112.01 ? 238 THR B OG1 1 ATOM 6162 C CG2 . THR B 2 227 ? -72.474 -37.870 -55.103 1.00 100.98 ? 238 THR B CG2 1 ATOM 6163 N N . ASP B 2 228 ? -73.490 -35.886 -58.190 1.00 113.61 ? 239 ASP B N 1 ATOM 6164 C CA . ASP B 2 228 ? -73.879 -34.486 -58.243 1.00 122.47 ? 239 ASP B CA 1 ATOM 6165 C C . ASP B 2 228 ? -75.280 -34.328 -57.677 1.00 125.76 ? 239 ASP B C 1 ATOM 6166 O O . ASP B 2 228 ? -75.813 -33.222 -57.584 1.00 123.14 ? 239 ASP B O 1 ATOM 6167 C CB . ASP B 2 228 ? -73.811 -33.962 -59.679 1.00 134.61 ? 239 ASP B CB 1 ATOM 6168 C CG . ASP B 2 228 ? -74.674 -34.768 -60.639 1.00 140.79 ? 239 ASP B CG 1 ATOM 6169 O OD1 . ASP B 2 228 ? -75.093 -34.210 -61.676 1.00 141.30 ? 239 ASP B OD1 1 ATOM 6170 O OD2 . ASP B 2 228 ? -74.939 -35.955 -60.353 1.00 138.68 ? 239 ASP B OD2 1 ATOM 6171 N N . LYS B 2 229 ? -75.870 -35.455 -57.299 1.00 127.51 ? 240 LYS B N 1 ATOM 6172 C CA . LYS B 2 229 ? -77.212 -35.477 -56.740 1.00 127.79 ? 240 LYS B CA 1 ATOM 6173 C C . LYS B 2 229 ? -77.154 -35.566 -55.218 1.00 125.11 ? 240 LYS B C 1 ATOM 6174 O O . LYS B 2 229 ? -76.248 -36.192 -54.665 1.00 127.39 ? 240 LYS B O 1 ATOM 6175 C CB . LYS B 2 229 ? -78.011 -36.652 -57.314 1.00 126.69 ? 240 LYS B CB 1 ATOM 6176 C CG . LYS B 2 229 ? -77.988 -36.736 -58.835 1.00 127.62 ? 240 LYS B CG 1 ATOM 6177 C CD . LYS B 2 229 ? -78.428 -35.424 -59.471 1.00 139.44 ? 240 LYS B CD 1 ATOM 6178 C CE . LYS B 2 229 ? -79.884 -35.106 -59.162 1.00 153.89 ? 240 LYS B CE 1 ATOM 6179 N NZ . LYS B 2 229 ? -80.298 -33.793 -59.732 1.00 162.81 ? 240 LYS B NZ 1 ATOM 6180 N N . PRO B 2 230 ? -78.115 -34.926 -54.533 1.00 118.12 ? 241 PRO B N 1 ATOM 6181 C CA . PRO B 2 230 ? -78.250 -35.098 -53.082 1.00 111.45 ? 241 PRO B CA 1 ATOM 6182 C C . PRO B 2 230 ? -78.482 -36.567 -52.746 1.00 108.47 ? 241 PRO B C 1 ATOM 6183 O O . PRO B 2 230 ? -78.933 -37.310 -53.618 1.00 113.42 ? 241 PRO B O 1 ATOM 6184 C CB . PRO B 2 230 ? -79.478 -34.248 -52.735 1.00 114.97 ? 241 PRO B CB 1 ATOM 6185 C CG . PRO B 2 230 ? -79.583 -33.262 -53.849 1.00 116.08 ? 241 PRO B CG 1 ATOM 6186 C CD . PRO B 2 230 ? -79.105 -33.978 -55.073 1.00 116.48 ? 241 PRO B CD 1 ATOM 6187 N N . PRO B 2 231 ? -78.178 -36.985 -51.505 1.00 101.39 ? 242 PRO B N 1 ATOM 6188 C CA . PRO B 2 231 ? -78.392 -38.378 -51.093 1.00 98.66 ? 242 PRO B CA 1 ATOM 6189 C C . PRO B 2 231 ? -79.845 -38.842 -51.239 1.00 99.44 ? 242 PRO B C 1 ATOM 6190 O O . PRO B 2 231 ? -80.715 -38.070 -51.643 1.00 95.06 ? 242 PRO B O 1 ATOM 6191 C CB . PRO B 2 231 ? -77.967 -38.374 -49.621 1.00 90.88 ? 242 PRO B CB 1 ATOM 6192 C CG . PRO B 2 231 ? -77.005 -37.254 -49.517 1.00 95.51 ? 242 PRO B CG 1 ATOM 6193 C CD . PRO B 2 231 ? -77.508 -36.200 -50.454 1.00 99.80 ? 242 PRO B CD 1 ATOM 6194 N N . LYS B 2 232 ? -80.098 -40.101 -50.898 1.00 101.57 ? 243 LYS B N 1 ATOM 6195 C CA . LYS B 2 232 ? -81.404 -40.710 -51.113 1.00 96.30 ? 243 LYS B CA 1 ATOM 6196 C C . LYS B 2 232 ? -81.907 -41.397 -49.848 1.00 92.11 ? 243 LYS B C 1 ATOM 6197 O O . LYS B 2 232 ? -81.257 -42.296 -49.318 1.00 91.27 ? 243 LYS B O 1 ATOM 6198 C CB . LYS B 2 232 ? -81.327 -41.707 -52.277 1.00 97.55 ? 243 LYS B CB 1 ATOM 6199 C CG . LYS B 2 232 ? -82.627 -42.408 -52.631 1.00 96.06 ? 243 LYS B CG 1 ATOM 6200 C CD . LYS B 2 232 ? -83.326 -41.747 -53.810 1.00 85.44 ? 243 LYS B CD 1 ATOM 6201 C CE . LYS B 2 232 ? -84.430 -42.645 -54.350 1.00 66.12 ? 243 LYS B CE 1 ATOM 6202 N NZ . LYS B 2 232 ? -85.357 -41.924 -55.261 1.00 58.81 ? 243 LYS B NZ 1 ATOM 6203 N N . LEU B 2 233 ? -83.062 -40.964 -49.358 1.00 86.12 ? 244 LEU B N 1 ATOM 6204 C CA . LEU B 2 233 ? -83.657 -41.581 -48.182 1.00 83.42 ? 244 LEU B CA 1 ATOM 6205 C C . LEU B 2 233 ? -84.281 -42.936 -48.530 1.00 84.96 ? 244 LEU B C 1 ATOM 6206 O O . LEU B 2 233 ? -84.759 -43.143 -49.646 1.00 87.18 ? 244 LEU B O 1 ATOM 6207 C CB . LEU B 2 233 ? -84.703 -40.650 -47.563 1.00 83.87 ? 244 LEU B CB 1 ATOM 6208 C CG . LEU B 2 233 ? -84.218 -39.379 -46.850 1.00 68.74 ? 244 LEU B CG 1 ATOM 6209 C CD1 . LEU B 2 233 ? -82.885 -39.632 -46.163 1.00 69.45 ? 244 LEU B CD1 1 ATOM 6210 C CD2 . LEU B 2 233 ? -84.133 -38.189 -47.797 1.00 68.22 ? 244 LEU B CD2 1 ATOM 6211 N N . LEU B 2 234 ? -84.260 -43.859 -47.573 1.00 85.56 ? 245 LEU B N 1 ATOM 6212 C CA . LEU B 2 234 ? -84.850 -45.186 -47.741 1.00 86.82 ? 245 LEU B CA 1 ATOM 6213 C C . LEU B 2 234 ? -85.924 -45.376 -46.658 1.00 96.35 ? 245 LEU B C 1 ATOM 6214 O O . LEU B 2 234 ? -87.117 -45.191 -46.914 1.00 95.84 ? 245 LEU B O 1 ATOM 6215 C CB . LEU B 2 234 ? -83.768 -46.276 -47.663 1.00 92.63 ? 245 LEU B CB 1 ATOM 6216 C CG . LEU B 2 234 ? -82.875 -46.585 -48.878 1.00 98.26 ? 245 LEU B CG 1 ATOM 6217 C CD1 . LEU B 2 234 ? -82.160 -45.360 -49.444 1.00 90.19 ? 245 LEU B CD1 1 ATOM 6218 C CD2 . LEU B 2 234 ? -81.860 -47.663 -48.516 1.00 103.01 ? 245 LEU B CD2 1 ATOM 6219 N N . TYR B 2 235 ? -85.487 -45.750 -45.457 1.00 100.01 ? 246 TYR B N 1 ATOM 6220 C CA . TYR B 2 235 ? -86.252 -45.517 -44.234 1.00 90.89 ? 246 TYR B CA 1 ATOM 6221 C C . TYR B 2 235 ? -85.851 -44.146 -43.685 1.00 80.10 ? 246 TYR B C 1 ATOM 6222 O O . TYR B 2 235 ? -84.724 -43.981 -43.221 1.00 78.23 ? 246 TYR B O 1 ATOM 6223 C CB . TYR B 2 235 ? -85.974 -46.586 -43.166 1.00 101.96 ? 246 TYR B CB 1 ATOM 6224 C CG . TYR B 2 235 ? -86.646 -47.940 -43.326 1.00 116.49 ? 246 TYR B CG 1 ATOM 6225 C CD1 . TYR B 2 235 ? -87.826 -48.088 -44.039 1.00 124.72 ? 246 TYR B CD1 1 ATOM 6226 C CD2 . TYR B 2 235 ? -86.097 -49.071 -42.728 1.00 119.69 ? 246 TYR B CD2 1 ATOM 6227 C CE1 . TYR B 2 235 ? -88.435 -49.337 -44.167 1.00 144.24 ? 246 TYR B CE1 1 ATOM 6228 C CE2 . TYR B 2 235 ? -86.691 -50.315 -42.850 1.00 128.46 ? 246 TYR B CE2 1 ATOM 6229 C CZ . TYR B 2 235 ? -87.859 -50.446 -43.569 1.00 139.46 ? 246 TYR B CZ 1 ATOM 6230 O OH . TYR B 2 235 ? -88.444 -51.690 -43.683 1.00 128.79 ? 246 TYR B OH 1 ATOM 6231 N N . PRO B 2 236 ? -86.753 -43.150 -43.734 1.00 69.88 ? 247 PRO B N 1 ATOM 6232 C CA . PRO B 2 236 ? -88.090 -43.121 -44.332 1.00 79.12 ? 247 PRO B CA 1 ATOM 6233 C C . PRO B 2 236 ? -88.102 -42.407 -45.685 1.00 84.77 ? 247 PRO B C 1 ATOM 6234 O O . PRO B 2 236 ? -87.184 -41.648 -45.972 1.00 85.15 ? 247 PRO B O 1 ATOM 6235 C CB . PRO B 2 236 ? -88.894 -42.340 -43.300 1.00 84.00 ? 247 PRO B CB 1 ATOM 6236 C CG . PRO B 2 236 ? -87.899 -41.355 -42.757 1.00 71.23 ? 247 PRO B CG 1 ATOM 6237 C CD . PRO B 2 236 ? -86.518 -41.957 -42.899 1.00 63.54 ? 247 PRO B CD 1 ATOM 6238 N N . MET B 2 237 ? -89.134 -42.628 -46.492 1.00 90.48 ? 248 MET B N 1 ATOM 6239 C CA . MET B 2 237 ? -89.218 -41.997 -47.805 1.00 82.12 ? 248 MET B CA 1 ATOM 6240 C C . MET B 2 237 ? -89.535 -40.508 -47.685 1.00 81.49 ? 248 MET B C 1 ATOM 6241 O O . MET B 2 237 ? -90.287 -40.092 -46.803 1.00 85.45 ? 248 MET B O 1 ATOM 6242 C CB . MET B 2 237 ? -90.264 -42.708 -48.669 1.00 86.21 ? 248 MET B CB 1 ATOM 6243 C CG . MET B 2 237 ? -89.936 -44.176 -48.909 1.00 90.44 ? 248 MET B CG 1 ATOM 6244 S SD . MET B 2 237 ? -91.344 -45.186 -49.403 1.00 107.30 ? 248 MET B SD 1 ATOM 6245 C CE . MET B 2 237 ? -90.559 -46.791 -49.534 1.00 126.61 ? 248 MET B CE 1 ATOM 6246 N N . GLU B 2 238 ? -88.960 -39.709 -48.581 1.00 80.28 ? 249 GLU B N 1 ATOM 6247 C CA . GLU B 2 238 ? -89.027 -38.248 -48.487 1.00 89.78 ? 249 GLU B CA 1 ATOM 6248 C C . GLU B 2 238 ? -90.450 -37.680 -48.623 1.00 80.85 ? 249 GLU B C 1 ATOM 6249 O O . GLU B 2 238 ? -90.695 -36.507 -48.323 1.00 68.68 ? 249 GLU B O 1 ATOM 6250 C CB . GLU B 2 238 ? -88.107 -37.626 -49.544 1.00 91.62 ? 249 GLU B CB 1 ATOM 6251 C CG . GLU B 2 238 ? -87.827 -36.143 -49.348 1.00 95.20 ? 249 GLU B CG 1 ATOM 6252 C CD . GLU B 2 238 ? -86.683 -35.640 -50.210 1.00 95.47 ? 249 GLU B CD 1 ATOM 6253 O OE1 . GLU B 2 238 ? -85.753 -36.428 -50.483 1.00 96.98 ? 249 GLU B OE1 1 ATOM 6254 O OE2 . GLU B 2 238 ? -86.713 -34.457 -50.613 1.00 90.13 ? 249 GLU B OE2 1 ATOM 6255 N N . SER B 2 239 ? -91.384 -38.518 -49.062 1.00 85.11 ? 250 SER B N 1 ATOM 6256 C CA . SER B 2 239 ? -92.783 -38.118 -49.189 1.00 94.59 ? 250 SER B CA 1 ATOM 6257 C C . SER B 2 239 ? -93.671 -38.880 -48.210 1.00 100.45 ? 250 SER B C 1 ATOM 6258 O O . SER B 2 239 ? -94.420 -38.280 -47.439 1.00 109.69 ? 250 SER B O 1 ATOM 6259 C CB . SER B 2 239 ? -93.277 -38.340 -50.620 1.00 101.48 ? 250 SER B CB 1 ATOM 6260 O OG . SER B 2 239 ? -94.606 -37.872 -50.787 1.00 103.64 ? 250 SER B OG 1 ATOM 6261 N N . LYS B 2 240 ? -93.576 -40.206 -48.257 1.00 98.41 ? 251 LYS B N 1 ATOM 6262 C CA . LYS B 2 240 ? -94.366 -41.083 -47.401 1.00 102.20 ? 251 LYS B CA 1 ATOM 6263 C C . LYS B 2 240 ? -94.224 -40.748 -45.922 1.00 100.82 ? 251 LYS B C 1 ATOM 6264 O O . LYS B 2 240 ? -93.216 -41.074 -45.294 1.00 100.69 ? 251 LYS B O 1 ATOM 6265 C CB . LYS B 2 240 ? -93.973 -42.544 -47.633 1.00 103.13 ? 251 LYS B CB 1 ATOM 6266 C CG . LYS B 2 240 ? -94.247 -43.049 -49.037 1.00 109.00 ? 251 LYS B CG 1 ATOM 6267 C CD . LYS B 2 240 ? -95.685 -42.772 -49.452 1.00 114.55 ? 251 LYS B CD 1 ATOM 6268 C CE . LYS B 2 240 ? -96.127 -43.720 -50.550 1.00 122.84 ? 251 LYS B CE 1 ATOM 6269 N NZ . LYS B 2 240 ? -96.020 -45.132 -50.093 1.00 142.19 ? 251 LYS B NZ 1 ATOM 6270 N N . LEU B 2 241 ? -95.234 -40.085 -45.370 1.00 94.15 ? 252 LEU B N 1 ATOM 6271 C CA . LEU B 2 241 ? -95.292 -39.889 -43.932 1.00 87.45 ? 252 LEU B CA 1 ATOM 6272 C C . LEU B 2 241 ? -95.533 -41.250 -43.301 1.00 88.65 ? 252 LEU B C 1 ATOM 6273 O O . LEU B 2 241 ? -96.664 -41.735 -43.263 1.00 85.00 ? 252 LEU B O 1 ATOM 6274 C CB . LEU B 2 241 ? -96.384 -38.892 -43.538 1.00 84.57 ? 252 LEU B CB 1 ATOM 6275 C CG . LEU B 2 241 ? -96.199 -38.280 -42.143 1.00 87.78 ? 252 LEU B CG 1 ATOM 6276 C CD1 . LEU B 2 241 ? -94.776 -37.784 -41.972 1.00 83.22 ? 252 LEU B CD1 1 ATOM 6277 C CD2 . LEU B 2 241 ? -97.189 -37.150 -41.875 1.00 85.90 ? 252 LEU B CD2 1 ATOM 6278 N N . THR B 2 242 ? -94.448 -41.873 -42.847 1.00 90.35 ? 253 THR B N 1 ATOM 6279 C CA . THR B 2 242 ? -94.505 -43.192 -42.231 1.00 92.06 ? 253 THR B CA 1 ATOM 6280 C C . THR B 2 242 ? -94.625 -43.034 -40.719 1.00 92.38 ? 253 THR B C 1 ATOM 6281 O O . THR B 2 242 ? -94.166 -42.041 -40.156 1.00 93.55 ? 253 THR B O 1 ATOM 6282 C CB . THR B 2 242 ? -93.261 -44.049 -42.591 1.00 92.87 ? 253 THR B CB 1 ATOM 6283 O OG1 . THR B 2 242 ? -92.079 -43.475 -42.015 1.00 92.57 ? 253 THR B OG1 1 ATOM 6284 C CG2 . THR B 2 242 ? -93.100 -44.143 -44.111 1.00 92.48 ? 253 THR B CG2 1 ATOM 6285 N N . VAL B 2 243 ? -95.260 -44.000 -40.064 1.00 83.65 ? 254 VAL B N 1 ATOM 6286 C CA . VAL B 2 243 ? -95.526 -43.896 -38.635 1.00 74.91 ? 254 VAL B CA 1 ATOM 6287 C C . VAL B 2 243 ? -94.989 -45.107 -37.873 1.00 90.35 ? 254 VAL B C 1 ATOM 6288 O O . VAL B 2 243 ? -95.138 -46.249 -38.309 1.00 99.70 ? 254 VAL B O 1 ATOM 6289 C CB . VAL B 2 243 ? -97.042 -43.742 -38.361 1.00 67.33 ? 254 VAL B CB 1 ATOM 6290 C CG1 . VAL B 2 243 ? -97.302 -43.515 -36.882 1.00 85.25 ? 254 VAL B CG1 1 ATOM 6291 C CG2 . VAL B 2 243 ? -97.615 -42.594 -39.170 1.00 69.20 ? 254 VAL B CG2 1 ATOM 6292 N N . GLN B 2 244 ? -94.349 -44.837 -36.738 1.00 90.28 ? 255 GLN B N 1 ATOM 6293 C CA . GLN B 2 244 ? -93.872 -45.872 -35.831 1.00 82.84 ? 255 GLN B CA 1 ATOM 6294 C C . GLN B 2 244 ? -94.750 -45.948 -34.590 1.00 84.71 ? 255 GLN B C 1 ATOM 6295 O O . GLN B 2 244 ? -94.994 -44.940 -33.926 1.00 86.52 ? 255 GLN B O 1 ATOM 6296 C CB . GLN B 2 244 ? -92.420 -45.609 -35.425 1.00 78.27 ? 255 GLN B CB 1 ATOM 6297 C CG . GLN B 2 244 ? -91.389 -46.298 -36.294 1.00 87.45 ? 255 GLN B CG 1 ATOM 6298 C CD . GLN B 2 244 ? -90.834 -47.558 -35.652 1.00 97.84 ? 255 GLN B CD 1 ATOM 6299 O OE1 . GLN B 2 244 ? -91.582 -48.468 -35.284 1.00 94.82 ? 255 GLN B OE1 1 ATOM 6300 N NE2 . GLN B 2 244 ? -89.513 -47.611 -35.504 1.00 93.64 ? 255 GLN B NE2 1 ATOM 6301 N N . GLU B 2 245 ? -95.231 -47.146 -34.283 1.00 82.85 ? 256 GLU B N 1 ATOM 6302 C CA . GLU B 2 245 ? -96.008 -47.358 -33.072 1.00 95.07 ? 256 GLU B CA 1 ATOM 6303 C C . GLU B 2 245 ? -95.088 -47.489 -31.867 1.00 111.69 ? 256 GLU B C 1 ATOM 6304 O O . GLU B 2 245 ? -93.997 -48.051 -31.963 1.00 121.65 ? 256 GLU B O 1 ATOM 6305 C CB . GLU B 2 245 ? -96.892 -48.604 -33.202 1.00 110.13 ? 256 GLU B CB 1 ATOM 6306 C CG . GLU B 2 245 ? -98.143 -48.408 -34.051 1.00 108.17 ? 256 GLU B CG 1 ATOM 6307 C CD . GLU B 2 245 ? -99.128 -47.423 -33.441 1.00 104.24 ? 256 GLU B CD 1 ATOM 6308 O OE1 . GLU B 2 245 ? -98.999 -47.105 -32.239 1.00 106.91 ? 256 GLU B OE1 1 ATOM 6309 O OE2 . GLU B 2 245 ? -100.035 -46.964 -34.167 1.00 100.85 ? 256 GLU B OE2 1 ATOM 6310 N N . THR B 2 246 ? -95.530 -46.954 -30.735 1.00 115.77 ? 257 THR B N 1 ATOM 6311 C CA . THR B 2 246 ? -94.824 -47.129 -29.478 1.00 104.64 ? 257 THR B CA 1 ATOM 6312 C C . THR B 2 246 ? -95.829 -46.991 -28.341 1.00 112.14 ? 257 THR B C 1 ATOM 6313 O O . THR B 2 246 ? -96.910 -46.429 -28.518 1.00 116.00 ? 257 THR B O 1 ATOM 6314 C CB . THR B 2 246 ? -93.659 -46.107 -29.306 1.00 79.90 ? 257 THR B CB 1 ATOM 6315 O OG1 . THR B 2 246 ? -92.610 -46.691 -28.522 1.00 61.19 ? 257 THR B OG1 1 ATOM 6316 C CG2 . THR B 2 246 ? -94.136 -44.817 -28.643 1.00 81.52 ? 257 THR B CG2 1 ATOM 6317 N N . GLN B 2 247 ? -95.490 -47.552 -27.189 1.00 116.01 ? 258 GLN B N 1 ATOM 6318 C CA . GLN B 2 247 ? -96.241 -47.304 -25.976 1.00 107.21 ? 258 GLN B CA 1 ATOM 6319 C C . GLN B 2 247 ? -95.337 -46.500 -25.057 1.00 91.17 ? 258 GLN B C 1 ATOM 6320 O O . GLN B 2 247 ? -94.109 -46.581 -25.157 1.00 90.70 ? 258 GLN B O 1 ATOM 6321 C CB . GLN B 2 247 ? -96.684 -48.615 -25.317 1.00 98.46 ? 258 GLN B CB 1 ATOM 6322 C CG . GLN B 2 247 ? -97.187 -49.663 -26.295 1.00 96.92 ? 258 GLN B CG 1 ATOM 6323 C CD . GLN B 2 247 ? -96.708 -51.063 -25.949 1.00 96.90 ? 258 GLN B CD 1 ATOM 6324 O OE1 . GLN B 2 247 ? -96.035 -51.272 -24.938 1.00 85.55 ? 258 GLN B OE1 1 ATOM 6325 N NE2 . GLN B 2 247 ? -97.048 -52.029 -26.795 1.00 102.78 ? 258 GLN B NE2 1 ATOM 6326 N N . LEU B 2 248 ? -95.945 -45.703 -24.188 1.00 75.31 ? 259 LEU B N 1 ATOM 6327 C CA . LEU B 2 248 ? -95.212 -44.974 -23.164 1.00 70.29 ? 259 LEU B CA 1 ATOM 6328 C C . LEU B 2 248 ? -94.388 -45.943 -22.313 1.00 72.39 ? 259 LEU B C 1 ATOM 6329 O O . LEU B 2 248 ? -94.744 -47.113 -22.170 1.00 69.94 ? 259 LEU B O 1 ATOM 6330 C CB . LEU B 2 248 ? -96.186 -44.186 -22.289 1.00 74.78 ? 259 LEU B CB 1 ATOM 6331 C CG . LEU B 2 248 ? -97.143 -43.256 -23.049 1.00 67.92 ? 259 LEU B CG 1 ATOM 6332 C CD1 . LEU B 2 248 ? -98.397 -42.974 -22.237 1.00 68.26 ? 259 LEU B CD1 1 ATOM 6333 C CD2 . LEU B 2 248 ? -96.443 -41.961 -23.402 1.00 84.79 ? 259 LEU B CD2 1 ATOM 6334 N N . GLY B 2 249 ? -93.276 -45.464 -21.765 1.00 76.02 ? 260 GLY B N 1 ATOM 6335 C CA . GLY B 2 249 ? -92.440 -46.277 -20.897 1.00 77.40 ? 260 GLY B CA 1 ATOM 6336 C C . GLY B 2 249 ? -91.592 -47.313 -21.618 1.00 74.70 ? 260 GLY B C 1 ATOM 6337 O O . GLY B 2 249 ? -90.665 -47.877 -21.037 1.00 77.83 ? 260 GLY B O 1 ATOM 6338 N N . GLY B 2 250 ? -91.905 -47.576 -22.883 1.00 68.41 ? 261 GLY B N 1 ATOM 6339 C CA . GLY B 2 250 ? -91.094 -48.475 -23.684 1.00 73.42 ? 261 GLY B CA 1 ATOM 6340 C C . GLY B 2 250 ? -89.844 -47.754 -24.157 1.00 78.58 ? 261 GLY B C 1 ATOM 6341 O O . GLY B 2 250 ? -89.649 -46.585 -23.837 1.00 71.40 ? 261 GLY B O 1 ATOM 6342 N N . SER B 2 251 ? -88.990 -48.446 -24.908 1.00 84.94 ? 262 SER B N 1 ATOM 6343 C CA . SER B 2 251 ? -87.836 -47.805 -25.541 1.00 87.67 ? 262 SER B CA 1 ATOM 6344 C C . SER B 2 251 ? -88.067 -47.727 -27.054 1.00 98.52 ? 262 SER B C 1 ATOM 6345 O O . SER B 2 251 ? -88.752 -48.577 -27.626 1.00 98.12 ? 262 SER B O 1 ATOM 6346 C CB . SER B 2 251 ? -86.533 -48.551 -25.219 1.00 84.37 ? 262 SER B CB 1 ATOM 6347 O OG . SER B 2 251 ? -86.457 -49.797 -25.884 1.00 91.13 ? 262 SER B OG 1 ATOM 6348 N N . ALA B 2 252 ? -87.500 -46.711 -27.701 1.00 97.47 ? 263 ALA B N 1 ATOM 6349 C CA . ALA B 2 252 ? -87.800 -46.449 -29.110 1.00 86.13 ? 263 ALA B CA 1 ATOM 6350 C C . ALA B 2 252 ? -86.564 -46.444 -30.014 1.00 86.12 ? 263 ALA B C 1 ATOM 6351 O O . ALA B 2 252 ? -85.534 -45.860 -29.677 1.00 84.60 ? 263 ALA B O 1 ATOM 6352 C CB . ALA B 2 252 ? -88.546 -45.123 -29.243 1.00 75.19 ? 263 ALA B CB 1 ATOM 6353 N N . ASN B 2 253 ? -86.689 -47.095 -31.169 1.00 87.01 ? 264 ASN B N 1 ATOM 6354 C CA . ASN B 2 253 ? -85.621 -47.161 -32.166 1.00 84.74 ? 264 ASN B CA 1 ATOM 6355 C C . ASN B 2 253 ? -86.108 -46.680 -33.533 1.00 76.71 ? 264 ASN B C 1 ATOM 6356 O O . ASN B 2 253 ? -86.763 -47.420 -34.269 1.00 68.94 ? 264 ASN B O 1 ATOM 6357 C CB . ASN B 2 253 ? -85.079 -48.593 -32.275 1.00 98.20 ? 264 ASN B CB 1 ATOM 6358 C CG . ASN B 2 253 ? -83.739 -48.672 -33.005 1.00 97.09 ? 264 ASN B CG 1 ATOM 6359 O OD1 . ASN B 2 253 ? -83.295 -47.709 -33.628 1.00 86.93 ? 264 ASN B OD1 1 ATOM 6360 N ND2 . ASN B 2 253 ? -83.091 -49.836 -32.922 1.00 106.46 ? 264 ASN B ND2 1 ATOM 6361 N N . LEU B 2 254 ? -85.789 -45.433 -33.863 1.00 80.29 ? 265 LEU B N 1 ATOM 6362 C CA . LEU B 2 254 ? -86.120 -44.864 -35.167 1.00 85.34 ? 265 LEU B CA 1 ATOM 6363 C C . LEU B 2 254 ? -84.895 -44.889 -36.085 1.00 90.81 ? 265 LEU B C 1 ATOM 6364 O O . LEU B 2 254 ? -84.103 -43.947 -36.106 1.00 89.09 ? 265 LEU B O 1 ATOM 6365 C CB . LEU B 2 254 ? -86.650 -43.435 -35.008 1.00 78.95 ? 265 LEU B CB 1 ATOM 6366 C CG . LEU B 2 254 ? -88.158 -43.235 -35.198 1.00 75.20 ? 265 LEU B CG 1 ATOM 6367 C CD1 . LEU B 2 254 ? -88.952 -44.241 -34.378 1.00 74.83 ? 265 LEU B CD1 1 ATOM 6368 C CD2 . LEU B 2 254 ? -88.574 -41.809 -34.848 1.00 75.26 ? 265 LEU B CD2 1 ATOM 6369 N N . THR B 2 255 ? -84.743 -45.974 -36.840 1.00 89.64 ? 266 THR B N 1 ATOM 6370 C CA . THR B 2 255 ? -83.539 -46.197 -37.634 1.00 82.94 ? 266 THR B CA 1 ATOM 6371 C C . THR B 2 255 ? -83.645 -45.586 -39.025 1.00 82.89 ? 266 THR B C 1 ATOM 6372 O O . THR B 2 255 ? -84.329 -46.121 -39.897 1.00 88.56 ? 266 THR B O 1 ATOM 6373 C CB . THR B 2 255 ? -83.234 -47.705 -37.769 1.00 87.68 ? 266 THR B CB 1 ATOM 6374 O OG1 . THR B 2 255 ? -83.563 -48.372 -36.546 1.00 96.32 ? 266 THR B OG1 1 ATOM 6375 C CG2 . THR B 2 255 ? -81.765 -47.933 -38.075 1.00 96.44 ? 266 THR B CG2 1 ATOM 6376 N N . CYS B 2 256 ? -82.972 -44.457 -39.226 1.00 80.38 ? 267 CYS B N 1 ATOM 6377 C CA . CYS B 2 256 ? -82.890 -43.855 -40.549 1.00 80.28 ? 267 CYS B CA 1 ATOM 6378 C C . CYS B 2 256 ? -81.950 -44.665 -41.418 1.00 83.54 ? 267 CYS B C 1 ATOM 6379 O O . CYS B 2 256 ? -81.000 -45.275 -40.929 1.00 88.64 ? 267 CYS B O 1 ATOM 6380 C CB . CYS B 2 256 ? -82.409 -42.402 -40.490 1.00 75.45 ? 267 CYS B CB 1 ATOM 6381 S SG . CYS B 2 256 ? -82.558 -41.530 -42.074 1.00 41.62 ? 267 CYS B SG 1 ATOM 6382 N N . ARG B 2 257 ? -82.217 -44.656 -42.715 1.00 80.74 ? 268 ARG B N 1 ATOM 6383 C CA . ARG B 2 257 ? -81.420 -45.405 -43.667 1.00 87.75 ? 268 ARG B CA 1 ATOM 6384 C C . ARG B 2 257 ? -81.361 -44.632 -44.972 1.00 96.48 ? 268 ARG B C 1 ATOM 6385 O O . ARG B 2 257 ? -82.393 -44.347 -45.579 1.00 96.40 ? 268 ARG B O 1 ATOM 6386 C CB . ARG B 2 257 ? -82.014 -46.794 -43.875 1.00 84.67 ? 268 ARG B CB 1 ATOM 6387 C CG . ARG B 2 257 ? -81.310 -47.634 -44.908 1.00 88.56 ? 268 ARG B CG 1 ATOM 6388 C CD . ARG B 2 257 ? -82.079 -48.918 -45.105 1.00 95.41 ? 268 ARG B CD 1 ATOM 6389 N NE . ARG B 2 257 ? -82.376 -49.556 -43.826 1.00 101.08 ? 268 ARG B NE 1 ATOM 6390 C CZ . ARG B 2 257 ? -83.312 -50.482 -43.647 1.00 108.27 ? 268 ARG B CZ 1 ATOM 6391 N NH1 . ARG B 2 257 ? -84.061 -50.876 -44.668 1.00 108.26 ? 268 ARG B NH1 1 ATOM 6392 N NH2 . ARG B 2 257 ? -83.506 -51.003 -42.443 1.00 112.38 ? 268 ARG B NH2 1 ATOM 6393 N N . ALA B 2 258 ? -80.156 -44.273 -45.398 1.00 101.20 ? 269 ALA B N 1 ATOM 6394 C CA . ALA B 2 258 ? -80.008 -43.454 -46.593 1.00 96.65 ? 269 ALA B CA 1 ATOM 6395 C C . ALA B 2 258 ? -78.792 -43.837 -47.430 1.00 102.68 ? 269 ALA B C 1 ATOM 6396 O O . ALA B 2 258 ? -77.896 -44.548 -46.973 1.00 97.36 ? 269 ALA B O 1 ATOM 6397 C CB . ALA B 2 258 ? -79.943 -41.986 -46.213 1.00 92.73 ? 269 ALA B CB 1 ATOM 6398 N N . PHE B 2 259 ? -78.778 -43.334 -48.660 1.00 108.50 ? 270 PHE B N 1 ATOM 6399 C CA . PHE B 2 259 ? -77.790 -43.702 -49.664 1.00 105.68 ? 270 PHE B CA 1 ATOM 6400 C C . PHE B 2 259 ? -77.001 -42.485 -50.145 1.00 100.49 ? 270 PHE B C 1 ATOM 6401 O O . PHE B 2 259 ? -77.579 -41.455 -50.492 1.00 100.12 ? 270 PHE B O 1 ATOM 6402 C CB . PHE B 2 259 ? -78.488 -44.396 -50.841 1.00 99.33 ? 270 PHE B CB 1 ATOM 6403 C CG . PHE B 2 259 ? -77.639 -44.524 -52.073 1.00 89.56 ? 270 PHE B CG 1 ATOM 6404 C CD1 . PHE B 2 259 ? -77.771 -43.623 -53.116 1.00 85.48 ? 270 PHE B CD1 1 ATOM 6405 C CD2 . PHE B 2 259 ? -76.726 -45.556 -52.197 1.00 94.41 ? 270 PHE B CD2 1 ATOM 6406 C CE1 . PHE B 2 259 ? -77.000 -43.742 -54.249 1.00 94.19 ? 270 PHE B CE1 1 ATOM 6407 C CE2 . PHE B 2 259 ? -75.953 -45.680 -53.330 1.00 92.79 ? 270 PHE B CE2 1 ATOM 6408 C CZ . PHE B 2 259 ? -76.089 -44.773 -54.358 1.00 97.99 ? 270 PHE B CZ 1 ATOM 6409 N N . PHE B 2 260 ? -75.679 -42.615 -50.164 1.00 95.51 ? 271 PHE B N 1 ATOM 6410 C CA . PHE B 2 260 ? -74.804 -41.535 -50.602 1.00 92.96 ? 271 PHE B CA 1 ATOM 6411 C C . PHE B 2 260 ? -74.030 -41.931 -51.854 1.00 92.06 ? 271 PHE B C 1 ATOM 6412 O O . PHE B 2 260 ? -73.468 -43.022 -51.923 1.00 97.11 ? 271 PHE B O 1 ATOM 6413 C CB . PHE B 2 260 ? -73.821 -41.149 -49.487 1.00 96.35 ? 271 PHE B CB 1 ATOM 6414 C CG . PHE B 2 260 ? -74.445 -40.377 -48.352 1.00 98.31 ? 271 PHE B CG 1 ATOM 6415 C CD1 . PHE B 2 260 ? -74.112 -39.048 -48.132 1.00 99.50 ? 271 PHE B CD1 1 ATOM 6416 C CD2 . PHE B 2 260 ? -75.359 -40.979 -47.504 1.00 100.35 ? 271 PHE B CD2 1 ATOM 6417 C CE1 . PHE B 2 260 ? -74.681 -38.337 -47.089 1.00 100.58 ? 271 PHE B CE1 1 ATOM 6418 C CE2 . PHE B 2 260 ? -75.933 -40.273 -46.464 1.00 96.34 ? 271 PHE B CE2 1 ATOM 6419 C CZ . PHE B 2 260 ? -75.591 -38.951 -46.254 1.00 95.65 ? 271 PHE B CZ 1 ATOM 6420 N N . GLY B 2 261 ? -74.007 -41.049 -52.848 1.00 85.64 ? 272 GLY B N 1 ATOM 6421 C CA . GLY B 2 261 ? -73.094 -41.211 -53.963 1.00 86.08 ? 272 GLY B CA 1 ATOM 6422 C C . GLY B 2 261 ? -71.711 -40.807 -53.489 1.00 88.89 ? 272 GLY B C 1 ATOM 6423 O O . GLY B 2 261 ? -71.587 -40.135 -52.464 1.00 102.22 ? 272 GLY B O 1 ATOM 6424 N N . TYR B 2 262 ? -70.674 -41.217 -54.216 1.00 79.74 ? 273 TYR B N 1 ATOM 6425 C CA . TYR B 2 262 ? -69.298 -40.882 -53.851 1.00 84.60 ? 273 TYR B CA 1 ATOM 6426 C C . TYR B 2 262 ? -69.102 -39.367 -53.751 1.00 96.40 ? 273 TYR B C 1 ATOM 6427 O O . TYR B 2 262 ? -69.273 -38.646 -54.732 1.00 101.56 ? 273 TYR B O 1 ATOM 6428 C CB . TYR B 2 262 ? -68.313 -41.479 -54.863 1.00 87.09 ? 273 TYR B CB 1 ATOM 6429 C CG . TYR B 2 262 ? -66.862 -41.211 -54.530 1.00 93.98 ? 273 TYR B CG 1 ATOM 6430 C CD1 . TYR B 2 262 ? -66.271 -41.794 -53.418 1.00 99.34 ? 273 TYR B CD1 1 ATOM 6431 C CD2 . TYR B 2 262 ? -66.083 -40.378 -55.327 1.00 98.73 ? 273 TYR B CD2 1 ATOM 6432 C CE1 . TYR B 2 262 ? -64.947 -41.555 -53.102 1.00 108.23 ? 273 TYR B CE1 1 ATOM 6433 C CE2 . TYR B 2 262 ? -64.752 -40.132 -55.020 1.00 99.58 ? 273 TYR B CE2 1 ATOM 6434 C CZ . TYR B 2 262 ? -64.191 -40.725 -53.905 1.00 103.13 ? 273 TYR B CZ 1 ATOM 6435 O OH . TYR B 2 262 ? -62.873 -40.489 -53.589 1.00 93.31 ? 273 TYR B OH 1 ATOM 6436 N N . SER B 2 263 ? -68.760 -38.892 -52.555 1.00 100.99 ? 274 SER B N 1 ATOM 6437 C CA . SER B 2 263 ? -68.546 -37.466 -52.314 1.00 98.88 ? 274 SER B CA 1 ATOM 6438 C C . SER B 2 263 ? -67.125 -37.209 -51.818 1.00 96.69 ? 274 SER B C 1 ATOM 6439 O O . SER B 2 263 ? -66.852 -36.197 -51.170 1.00 100.46 ? 274 SER B O 1 ATOM 6440 C CB . SER B 2 263 ? -69.565 -36.925 -51.303 1.00 100.50 ? 274 SER B CB 1 ATOM 6441 O OG . SER B 2 263 ? -70.864 -36.850 -51.868 1.00 95.43 ? 274 SER B OG 1 ATOM 6442 N N . GLY B 2 264 ? -66.226 -38.136 -52.126 1.00 99.06 ? 275 GLY B N 1 ATOM 6443 C CA . GLY B 2 264 ? -64.845 -38.041 -51.694 1.00 102.70 ? 275 GLY B CA 1 ATOM 6444 C C . GLY B 2 264 ? -64.634 -38.661 -50.327 1.00 111.65 ? 275 GLY B C 1 ATOM 6445 O O . GLY B 2 264 ? -65.411 -39.512 -49.892 1.00 113.62 ? 275 GLY B O 1 ATOM 6446 N N . ASP B 2 265 ? -63.583 -38.224 -49.643 1.00 118.96 ? 276 ASP B N 1 ATOM 6447 C CA . ASP B 2 265 ? -63.241 -38.757 -48.328 1.00 130.73 ? 276 ASP B CA 1 ATOM 6448 C C . ASP B 2 265 ? -64.167 -38.219 -47.234 1.00 131.12 ? 276 ASP B C 1 ATOM 6449 O O . ASP B 2 265 ? -64.158 -38.717 -46.106 1.00 127.58 ? 276 ASP B O 1 ATOM 6450 C CB . ASP B 2 265 ? -61.781 -38.437 -47.988 1.00 133.35 ? 276 ASP B CB 1 ATOM 6451 C CG . ASP B 2 265 ? -61.268 -39.228 -46.797 1.00 132.80 ? 276 ASP B CG 1 ATOM 6452 O OD1 . ASP B 2 265 ? -61.857 -40.283 -46.482 1.00 127.89 ? 276 ASP B OD1 1 ATOM 6453 O OD2 . ASP B 2 265 ? -60.270 -38.797 -46.182 1.00 134.28 ? 276 ASP B OD2 1 ATOM 6454 N N . VAL B 2 266 ? -64.957 -37.202 -47.572 1.00 130.17 ? 277 VAL B N 1 ATOM 6455 C CA . VAL B 2 266 ? -65.923 -36.626 -46.642 1.00 122.59 ? 277 VAL B CA 1 ATOM 6456 C C . VAL B 2 266 ? -66.833 -37.705 -46.060 1.00 119.89 ? 277 VAL B C 1 ATOM 6457 O O . VAL B 2 266 ? -67.456 -38.473 -46.797 1.00 118.19 ? 277 VAL B O 1 ATOM 6458 C CB . VAL B 2 266 ? -66.790 -35.539 -47.324 1.00 116.08 ? 277 VAL B CB 1 ATOM 6459 C CG1 . VAL B 2 266 ? -67.871 -35.041 -46.377 1.00 113.30 ? 277 VAL B CG1 1 ATOM 6460 C CG2 . VAL B 2 266 ? -65.922 -34.386 -47.807 1.00 114.28 ? 277 VAL B CG2 1 ATOM 6461 N N . SER B 2 267 ? -66.875 -37.776 -44.732 1.00 117.39 ? 278 SER B N 1 ATOM 6462 C CA . SER B 2 267 ? -67.771 -38.688 -44.031 1.00 111.82 ? 278 SER B CA 1 ATOM 6463 C C . SER B 2 267 ? -69.222 -38.266 -44.261 1.00 109.82 ? 278 SER B C 1 ATOM 6464 O O . SER B 2 267 ? -69.525 -37.070 -44.267 1.00 109.80 ? 278 SER B O 1 ATOM 6465 C CB . SER B 2 267 ? -67.440 -38.728 -42.532 1.00 112.27 ? 278 SER B CB 1 ATOM 6466 O OG . SER B 2 267 ? -67.129 -37.441 -42.031 1.00 117.78 ? 278 SER B OG 1 ATOM 6467 N N . PRO B 2 268 ? -70.120 -39.249 -44.459 1.00 95.05 ? 279 PRO B N 1 ATOM 6468 C CA . PRO B 2 268 ? -71.533 -38.990 -44.766 1.00 82.91 ? 279 PRO B CA 1 ATOM 6469 C C . PRO B 2 268 ? -72.183 -38.057 -43.753 1.00 76.96 ? 279 PRO B C 1 ATOM 6470 O O . PRO B 2 268 ? -71.886 -38.148 -42.565 1.00 78.64 ? 279 PRO B O 1 ATOM 6471 C CB . PRO B 2 268 ? -72.166 -40.384 -44.708 1.00 76.23 ? 279 PRO B CB 1 ATOM 6472 C CG . PRO B 2 268 ? -71.048 -41.314 -44.993 1.00 76.70 ? 279 PRO B CG 1 ATOM 6473 C CD . PRO B 2 268 ? -69.832 -40.692 -44.379 1.00 87.05 ? 279 PRO B CD 1 ATOM 6474 N N . LEU B 2 269 ? -73.043 -37.159 -44.216 1.00 78.91 ? 280 LEU B N 1 ATOM 6475 C CA . LEU B 2 269 ? -73.734 -36.263 -43.303 1.00 81.82 ? 280 LEU B CA 1 ATOM 6476 C C . LEU B 2 269 ? -75.210 -36.628 -43.203 1.00 90.45 ? 280 LEU B C 1 ATOM 6477 O O . LEU B 2 269 ? -76.034 -36.176 -44.000 1.00 89.25 ? 280 LEU B O 1 ATOM 6478 C CB . LEU B 2 269 ? -73.574 -34.805 -43.738 1.00 84.71 ? 280 LEU B CB 1 ATOM 6479 C CG . LEU B 2 269 ? -73.015 -33.865 -42.664 1.00 91.82 ? 280 LEU B CG 1 ATOM 6480 C CD1 . LEU B 2 269 ? -73.541 -32.455 -42.868 1.00 104.62 ? 280 LEU B CD1 1 ATOM 6481 C CD2 . LEU B 2 269 ? -73.343 -34.368 -41.264 1.00 96.47 ? 280 LEU B CD2 1 ATOM 6482 N N . ILE B 2 270 ? -75.531 -37.467 -42.223 1.00 95.04 ? 281 ILE B N 1 ATOM 6483 C CA . ILE B 2 270 ? -76.904 -37.872 -41.957 1.00 82.25 ? 281 ILE B CA 1 ATOM 6484 C C . ILE B 2 270 ? -77.209 -37.666 -40.472 1.00 77.69 ? 281 ILE B C 1 ATOM 6485 O O . ILE B 2 270 ? -76.394 -37.984 -39.601 1.00 76.98 ? 281 ILE B O 1 ATOM 6486 C CB . ILE B 2 270 ? -77.163 -39.349 -42.382 1.00 72.38 ? 281 ILE B CB 1 ATOM 6487 C CG1 . ILE B 2 270 ? -78.625 -39.738 -42.132 1.00 70.85 ? 281 ILE B CG1 1 ATOM 6488 C CG2 . ILE B 2 270 ? -76.187 -40.308 -41.688 1.00 72.05 ? 281 ILE B CG2 1 ATOM 6489 C CD1 . ILE B 2 270 ? -78.984 -41.134 -42.602 1.00 77.54 ? 281 ILE B CD1 1 ATOM 6490 N N . TYR B 2 271 ? -78.379 -37.104 -40.189 1.00 76.75 ? 282 TYR B N 1 ATOM 6491 C CA . TYR B 2 271 ? -78.733 -36.736 -38.825 1.00 84.52 ? 282 TYR B CA 1 ATOM 6492 C C . TYR B 2 271 ? -80.238 -36.537 -38.651 1.00 90.91 ? 282 TYR B C 1 ATOM 6493 O O . TYR B 2 271 ? -80.967 -36.338 -39.624 1.00 91.23 ? 282 TYR B O 1 ATOM 6494 C CB . TYR B 2 271 ? -77.985 -35.464 -38.416 1.00 85.86 ? 282 TYR B CB 1 ATOM 6495 C CG . TYR B 2 271 ? -78.382 -34.240 -39.208 1.00 88.18 ? 282 TYR B CG 1 ATOM 6496 C CD1 . TYR B 2 271 ? -79.278 -33.316 -38.686 1.00 98.73 ? 282 TYR B CD1 1 ATOM 6497 C CD2 . TYR B 2 271 ? -77.866 -34.011 -40.479 1.00 84.43 ? 282 TYR B CD2 1 ATOM 6498 C CE1 . TYR B 2 271 ? -79.648 -32.197 -39.400 1.00 94.09 ? 282 TYR B CE1 1 ATOM 6499 C CE2 . TYR B 2 271 ? -78.230 -32.893 -41.205 1.00 90.77 ? 282 TYR B CE2 1 ATOM 6500 C CZ . TYR B 2 271 ? -79.122 -31.987 -40.657 1.00 91.11 ? 282 TYR B CZ 1 ATOM 6501 O OH . TYR B 2 271 ? -79.499 -30.870 -41.366 1.00 97.32 ? 282 TYR B OH 1 ATOM 6502 N N . TRP B 2 272 ? -80.690 -36.594 -37.400 1.00 84.21 ? 283 TRP B N 1 ATOM 6503 C CA . TRP B 2 272 ? -82.099 -36.428 -37.059 1.00 69.94 ? 283 TRP B CA 1 ATOM 6504 C C . TRP B 2 272 ? -82.370 -35.065 -36.434 1.00 75.02 ? 283 TRP B C 1 ATOM 6505 O O . TRP B 2 272 ? -81.444 -34.380 -35.998 1.00 84.91 ? 283 TRP B O 1 ATOM 6506 C CB . TRP B 2 272 ? -82.546 -37.522 -36.088 1.00 66.42 ? 283 TRP B CB 1 ATOM 6507 C CG . TRP B 2 272 ? -82.752 -38.873 -36.693 1.00 60.89 ? 283 TRP B CG 1 ATOM 6508 C CD1 . TRP B 2 272 ? -81.817 -39.855 -36.859 1.00 64.87 ? 283 TRP B CD1 1 ATOM 6509 C CD2 . TRP B 2 272 ? -83.985 -39.404 -37.188 1.00 62.93 ? 283 TRP B CD2 1 ATOM 6510 N NE1 . TRP B 2 272 ? -82.392 -40.961 -37.436 1.00 65.29 ? 283 TRP B NE1 1 ATOM 6511 C CE2 . TRP B 2 272 ? -83.723 -40.710 -37.648 1.00 64.22 ? 283 TRP B CE2 1 ATOM 6512 C CE3 . TRP B 2 272 ? -85.287 -38.900 -37.291 1.00 66.33 ? 283 TRP B CE3 1 ATOM 6513 C CZ2 . TRP B 2 272 ? -84.714 -41.519 -38.202 1.00 67.78 ? 283 TRP B CZ2 1 ATOM 6514 C CZ3 . TRP B 2 272 ? -86.269 -39.704 -37.844 1.00 64.55 ? 283 TRP B CZ3 1 ATOM 6515 C CH2 . TRP B 2 272 ? -85.975 -40.998 -38.293 1.00 63.97 ? 283 TRP B CH2 1 ATOM 6516 N N . MET B 2 273 ? -83.645 -34.685 -36.380 1.00 70.56 ? 284 MET B N 1 ATOM 6517 C CA . MET B 2 273 ? -84.064 -33.468 -35.686 1.00 81.69 ? 284 MET B CA 1 ATOM 6518 C C . MET B 2 273 ? -85.505 -33.524 -35.186 1.00 82.80 ? 284 MET B C 1 ATOM 6519 O O . MET B 2 273 ? -86.364 -34.172 -35.784 1.00 81.98 ? 284 MET B O 1 ATOM 6520 C CB . MET B 2 273 ? -83.892 -32.243 -36.588 1.00 80.45 ? 284 MET B CB 1 ATOM 6521 C CG . MET B 2 273 ? -82.601 -31.485 -36.332 1.00 89.00 ? 284 MET B CG 1 ATOM 6522 S SD . MET B 2 273 ? -82.581 -29.847 -37.077 1.00 100.14 ? 284 MET B SD 1 ATOM 6523 C CE . MET B 2 273 ? -82.781 -30.262 -38.806 1.00 95.40 ? 284 MET B CE 1 ATOM 6524 N N . LYS B 2 274 ? -85.750 -32.833 -34.076 1.00 86.88 ? 285 LYS B N 1 ATOM 6525 C CA . LYS B 2 274 ? -87.089 -32.664 -33.522 1.00 88.31 ? 285 LYS B CA 1 ATOM 6526 C C . LYS B 2 274 ? -87.499 -31.199 -33.615 1.00 92.88 ? 285 LYS B C 1 ATOM 6527 O O . LYS B 2 274 ? -87.006 -30.365 -32.857 1.00 95.97 ? 285 LYS B O 1 ATOM 6528 C CB . LYS B 2 274 ? -87.139 -33.136 -32.066 1.00 97.14 ? 285 LYS B CB 1 ATOM 6529 C CG . LYS B 2 274 ? -88.496 -32.970 -31.395 1.00 102.58 ? 285 LYS B CG 1 ATOM 6530 C CD . LYS B 2 274 ? -88.441 -33.377 -29.927 1.00 100.21 ? 285 LYS B CD 1 ATOM 6531 C CE . LYS B 2 274 ? -89.803 -33.246 -29.259 1.00 92.37 ? 285 LYS B CE 1 ATOM 6532 N NZ . LYS B 2 274 ? -90.790 -34.236 -29.782 1.00 79.61 ? 285 LYS B NZ 1 ATOM 6533 N N . GLY B 2 275 ? -88.400 -30.890 -34.544 1.00 99.68 ? 286 GLY B N 1 ATOM 6534 C CA . GLY B 2 275 ? -88.800 -29.517 -34.798 1.00 108.96 ? 286 GLY B CA 1 ATOM 6535 C C . GLY B 2 275 ? -87.616 -28.655 -35.198 1.00 107.93 ? 286 GLY B C 1 ATOM 6536 O O . GLY B 2 275 ? -87.038 -28.831 -36.273 1.00 107.76 ? 286 GLY B O 1 ATOM 6537 N N . GLU B 2 276 ? -87.253 -27.718 -34.327 1.00 110.87 ? 287 GLU B N 1 ATOM 6538 C CA . GLU B 2 276 ? -86.062 -26.900 -34.531 1.00 115.52 ? 287 GLU B CA 1 ATOM 6539 C C . GLU B 2 276 ? -84.999 -27.215 -33.485 1.00 106.59 ? 287 GLU B C 1 ATOM 6540 O O . GLU B 2 276 ? -83.983 -26.525 -33.386 1.00 104.51 ? 287 GLU B O 1 ATOM 6541 C CB . GLU B 2 276 ? -86.409 -25.412 -34.498 1.00 132.38 ? 287 GLU B CB 1 ATOM 6542 C CG . GLU B 2 276 ? -87.174 -24.938 -35.717 1.00 140.24 ? 287 GLU B CG 1 ATOM 6543 C CD . GLU B 2 276 ? -86.890 -23.488 -36.048 1.00 151.11 ? 287 GLU B CD 1 ATOM 6544 O OE1 . GLU B 2 276 ? -85.987 -23.235 -36.873 1.00 146.58 ? 287 GLU B OE1 1 ATOM 6545 O OE2 . GLU B 2 276 ? -87.563 -22.603 -35.479 1.00 160.61 ? 287 GLU B OE2 1 ATOM 6546 N N . LYS B 2 277 ? -85.247 -28.259 -32.703 1.00 103.24 ? 288 LYS B N 1 ATOM 6547 C CA . LYS B 2 277 ? -84.262 -28.754 -31.755 1.00 105.40 ? 288 LYS B CA 1 ATOM 6548 C C . LYS B 2 277 ? -83.437 -29.870 -32.376 1.00 102.92 ? 288 LYS B C 1 ATOM 6549 O O . LYS B 2 277 ? -83.983 -30.799 -32.969 1.00 99.22 ? 288 LYS B O 1 ATOM 6550 C CB . LYS B 2 277 ? -84.937 -29.262 -30.477 1.00 114.06 ? 288 LYS B CB 1 ATOM 6551 C CG . LYS B 2 277 ? -85.340 -28.172 -29.501 1.00 120.86 ? 288 LYS B CG 1 ATOM 6552 C CD . LYS B 2 277 ? -85.875 -28.759 -28.202 1.00 122.50 ? 288 LYS B CD 1 ATOM 6553 C CE . LYS B 2 277 ? -86.255 -27.665 -27.215 1.00 115.37 ? 288 LYS B CE 1 ATOM 6554 N NZ . LYS B 2 277 ? -85.091 -26.798 -26.879 1.00 119.07 ? 288 LYS B NZ 1 ATOM 6555 N N . PHE B 2 278 ? -82.121 -29.778 -32.247 1.00 103.78 ? 289 PHE B N 1 ATOM 6556 C CA . PHE B 2 278 ? -81.268 -30.893 -32.615 1.00 105.12 ? 289 PHE B CA 1 ATOM 6557 C C . PHE B 2 278 ? -81.215 -31.873 -31.441 1.00 114.82 ? 289 PHE B C 1 ATOM 6558 O O . PHE B 2 278 ? -81.281 -31.460 -30.283 1.00 121.53 ? 289 PHE B O 1 ATOM 6559 C CB . PHE B 2 278 ? -79.870 -30.413 -33.000 1.00 114.84 ? 289 PHE B CB 1 ATOM 6560 C CG . PHE B 2 278 ? -78.921 -31.528 -33.302 1.00 137.09 ? 289 PHE B CG 1 ATOM 6561 C CD1 . PHE B 2 278 ? -78.950 -32.166 -34.531 1.00 138.06 ? 289 PHE B CD1 1 ATOM 6562 C CD2 . PHE B 2 278 ? -78.017 -31.958 -32.349 1.00 147.75 ? 289 PHE B CD2 1 ATOM 6563 C CE1 . PHE B 2 278 ? -78.081 -33.208 -34.808 1.00 138.99 ? 289 PHE B CE1 1 ATOM 6564 C CE2 . PHE B 2 278 ? -77.154 -33.000 -32.616 1.00 150.94 ? 289 PHE B CE2 1 ATOM 6565 C CZ . PHE B 2 278 ? -77.178 -33.622 -33.849 1.00 145.11 ? 289 PHE B CZ 1 ATOM 6566 N N . ILE B 2 279 ? -81.093 -33.164 -31.747 1.00 114.49 ? 290 ILE B N 1 ATOM 6567 C CA . ILE B 2 279 ? -81.261 -34.240 -30.763 1.00 117.93 ? 290 ILE B CA 1 ATOM 6568 C C . ILE B 2 279 ? -80.325 -34.192 -29.547 1.00 127.31 ? 290 ILE B C 1 ATOM 6569 O O . ILE B 2 279 ? -80.792 -34.156 -28.407 1.00 130.69 ? 290 ILE B O 1 ATOM 6570 C CB . ILE B 2 279 ? -81.089 -35.623 -31.434 1.00 103.57 ? 290 ILE B CB 1 ATOM 6571 C CG1 . ILE B 2 279 ? -82.255 -35.901 -32.387 1.00 95.36 ? 290 ILE B CG1 1 ATOM 6572 C CG2 . ILE B 2 279 ? -81.003 -36.722 -30.389 1.00 105.59 ? 290 ILE B CG2 1 ATOM 6573 C CD1 . ILE B 2 279 ? -83.611 -35.942 -31.710 1.00 87.46 ? 290 ILE B CD1 1 ATOM 6574 N N . GLU B 2 280 ? -79.017 -34.199 -29.792 1.00 127.20 ? 291 GLU B N 1 ATOM 6575 C CA . GLU B 2 280 ? -78.020 -34.332 -28.725 1.00 129.09 ? 291 GLU B CA 1 ATOM 6576 C C . GLU B 2 280 ? -78.168 -33.341 -27.569 1.00 134.81 ? 291 GLU B C 1 ATOM 6577 O O . GLU B 2 280 ? -77.923 -33.686 -26.411 1.00 137.01 ? 291 GLU B O 1 ATOM 6578 C CB . GLU B 2 280 ? -76.617 -34.203 -29.316 1.00 138.51 ? 291 GLU B CB 1 ATOM 6579 C CG . GLU B 2 280 ? -75.797 -35.471 -29.208 1.00 154.70 ? 291 GLU B CG 1 ATOM 6580 C CD . GLU B 2 280 ? -74.774 -35.598 -30.318 1.00 166.66 ? 291 GLU B CD 1 ATOM 6581 O OE1 . GLU B 2 280 ? -74.214 -36.699 -30.495 1.00 177.32 ? 291 GLU B OE1 1 ATOM 6582 O OE2 . GLU B 2 280 ? -74.535 -34.596 -31.015 1.00 159.21 ? 291 GLU B OE2 1 ATOM 6583 N N . ASP B 2 281 ? -78.564 -32.114 -27.894 1.00 135.24 ? 292 ASP B N 1 ATOM 6584 C CA . ASP B 2 281 ? -78.712 -31.046 -26.909 1.00 134.65 ? 292 ASP B CA 1 ATOM 6585 C C . ASP B 2 281 ? -79.947 -31.240 -26.023 1.00 134.65 ? 292 ASP B C 1 ATOM 6586 O O . ASP B 2 281 ? -79.973 -30.805 -24.871 1.00 140.90 ? 292 ASP B O 1 ATOM 6587 C CB . ASP B 2 281 ? -78.790 -29.689 -27.619 1.00 127.66 ? 292 ASP B CB 1 ATOM 6588 C CG . ASP B 2 281 ? -77.744 -29.537 -28.715 1.00 133.13 ? 292 ASP B CG 1 ATOM 6589 O OD1 . ASP B 2 281 ? -77.608 -28.419 -29.255 1.00 144.16 ? 292 ASP B OD1 1 ATOM 6590 O OD2 . ASP B 2 281 ? -77.057 -30.530 -29.036 1.00 131.25 ? 292 ASP B OD2 1 ATOM 6591 N N . LEU B 2 282 ? -80.961 -31.897 -26.577 1.00 129.31 ? 293 LEU B N 1 ATOM 6592 C CA . LEU B 2 282 ? -82.240 -32.118 -25.901 1.00 126.52 ? 293 LEU B CA 1 ATOM 6593 C C . LEU B 2 282 ? -82.151 -33.162 -24.786 1.00 136.31 ? 293 LEU B C 1 ATOM 6594 O O . LEU B 2 282 ? -82.798 -33.032 -23.743 1.00 137.40 ? 293 LEU B O 1 ATOM 6595 C CB . LEU B 2 282 ? -83.295 -32.541 -26.935 1.00 123.19 ? 293 LEU B CB 1 ATOM 6596 C CG . LEU B 2 282 ? -84.717 -32.960 -26.537 1.00 129.21 ? 293 LEU B CG 1 ATOM 6597 C CD1 . LEU B 2 282 ? -85.689 -32.575 -27.638 1.00 106.07 ? 293 LEU B CD1 1 ATOM 6598 C CD2 . LEU B 2 282 ? -84.817 -34.459 -26.263 1.00 130.74 ? 293 LEU B CD2 1 ATOM 6599 N N . ASP B 2 283 ? -81.328 -34.180 -25.021 1.00 138.03 ? 294 ASP B N 1 ATOM 6600 C CA . ASP B 2 283 ? -81.315 -35.427 -24.254 1.00 136.00 ? 294 ASP B CA 1 ATOM 6601 C C . ASP B 2 283 ? -81.356 -35.344 -22.722 1.00 132.11 ? 294 ASP B C 1 ATOM 6602 O O . ASP B 2 283 ? -82.437 -35.350 -22.128 1.00 121.44 ? 294 ASP B O 1 ATOM 6603 C CB . ASP B 2 283 ? -80.074 -36.237 -24.651 1.00 133.98 ? 294 ASP B CB 1 ATOM 6604 C CG . ASP B 2 283 ? -80.173 -37.693 -24.237 1.00 127.76 ? 294 ASP B CG 1 ATOM 6605 O OD1 . ASP B 2 283 ? -81.258 -38.103 -23.779 1.00 124.94 ? 294 ASP B OD1 1 ATOM 6606 O OD2 . ASP B 2 283 ? -79.175 -38.424 -24.381 1.00 122.59 ? 294 ASP B OD2 1 ATOM 6607 N N . GLU B 2 284 ? -80.166 -35.290 -22.119 1.00 135.25 ? 295 GLU B N 1 ATOM 6608 C CA . GLU B 2 284 ? -79.924 -35.566 -20.692 1.00 138.74 ? 295 GLU B CA 1 ATOM 6609 C C . GLU B 2 284 ? -80.061 -37.067 -20.412 1.00 138.21 ? 295 GLU B C 1 ATOM 6610 O O . GLU B 2 284 ? -80.632 -37.482 -19.403 1.00 136.49 ? 295 GLU B O 1 ATOM 6611 C CB . GLU B 2 284 ? -80.855 -34.750 -19.787 1.00 142.07 ? 295 GLU B CB 1 ATOM 6612 C CG . GLU B 2 284 ? -80.126 -33.802 -18.845 1.00 150.15 ? 295 GLU B CG 1 ATOM 6613 C CD . GLU B 2 284 ? -79.095 -32.937 -19.558 1.00 164.13 ? 295 GLU B CD 1 ATOM 6614 O OE1 . GLU B 2 284 ? -78.061 -32.621 -18.935 1.00 177.86 ? 295 GLU B OE1 1 ATOM 6615 O OE2 . GLU B 2 284 ? -79.320 -32.565 -20.730 1.00 161.01 ? 295 GLU B OE2 1 ATOM 6616 N N . ASN B 2 285 ? -79.501 -37.857 -21.326 1.00 140.32 ? 296 ASN B N 1 ATOM 6617 C CA . ASN B 2 285 ? -79.484 -39.324 -21.280 1.00 133.82 ? 296 ASN B CA 1 ATOM 6618 C C . ASN B 2 285 ? -80.863 -39.979 -21.190 1.00 122.68 ? 296 ASN B C 1 ATOM 6619 O O . ASN B 2 285 ? -81.158 -40.723 -20.253 1.00 121.64 ? 296 ASN B O 1 ATOM 6620 C CB . ASN B 2 285 ? -78.595 -39.810 -20.132 1.00 136.87 ? 296 ASN B CB 1 ATOM 6621 C CG . ASN B 2 285 ? -77.264 -40.358 -20.626 1.00 130.16 ? 296 ASN B CG 1 ATOM 6622 O OD1 . ASN B 2 285 ? -76.891 -40.156 -21.783 1.00 129.57 ? 296 ASN B OD1 1 ATOM 6623 N ND2 . ASN B 2 285 ? -76.545 -41.057 -19.754 1.00 123.77 ? 296 ASN B ND2 1 ATOM 6624 N N . ARG B 2 286 ? -81.688 -39.702 -22.196 1.00 115.91 ? 297 ARG B N 1 ATOM 6625 C CA . ARG B 2 286 ? -82.960 -40.387 -22.398 1.00 111.73 ? 297 ARG B CA 1 ATOM 6626 C C . ARG B 2 286 ? -83.207 -40.564 -23.903 1.00 117.14 ? 297 ARG B C 1 ATOM 6627 O O . ARG B 2 286 ? -83.731 -41.589 -24.341 1.00 115.53 ? 297 ARG B O 1 ATOM 6628 C CB . ARG B 2 286 ? -84.108 -39.608 -21.750 1.00 104.30 ? 297 ARG B CB 1 ATOM 6629 C CG . ARG B 2 286 ? -85.032 -40.455 -20.891 1.00 98.76 ? 297 ARG B CG 1 ATOM 6630 C CD . ARG B 2 286 ? -86.194 -39.629 -20.371 1.00 100.42 ? 297 ARG B CD 1 ATOM 6631 N NE . ARG B 2 286 ? -87.143 -39.285 -21.430 1.00 91.71 ? 297 ARG B NE 1 ATOM 6632 C CZ . ARG B 2 286 ? -87.815 -38.141 -21.490 1.00 96.41 ? 297 ARG B CZ 1 ATOM 6633 N NH1 . ARG B 2 286 ? -87.640 -37.216 -20.557 1.00 95.03 ? 297 ARG B NH1 1 ATOM 6634 N NH2 . ARG B 2 286 ? -88.659 -37.921 -22.486 1.00 103.81 ? 297 ARG B NH2 1 ATOM 6635 N N . VAL B 2 287 ? -82.804 -39.559 -24.682 1.00 116.34 ? 298 VAL B N 1 ATOM 6636 C CA . VAL B 2 287 ? -83.049 -39.505 -26.126 1.00 100.38 ? 298 VAL B CA 1 ATOM 6637 C C . VAL B 2 287 ? -81.791 -39.108 -26.905 1.00 98.85 ? 298 VAL B C 1 ATOM 6638 O O . VAL B 2 287 ? -81.371 -37.955 -26.864 1.00 102.28 ? 298 VAL B O 1 ATOM 6639 C CB . VAL B 2 287 ? -84.171 -38.501 -26.466 1.00 99.99 ? 298 VAL B CB 1 ATOM 6640 C CG1 . VAL B 2 287 ? -84.308 -38.339 -27.973 1.00 103.22 ? 298 VAL B CG1 1 ATOM 6641 C CG2 . VAL B 2 287 ? -85.491 -38.933 -25.851 1.00 101.20 ? 298 VAL B CG2 1 ATOM 6642 N N . TRP B 2 288 ? -81.202 -40.047 -27.639 1.00 99.10 ? 299 TRP B N 1 ATOM 6643 C CA . TRP B 2 288 ? -79.898 -39.792 -28.245 1.00 102.93 ? 299 TRP B CA 1 ATOM 6644 C C . TRP B 2 288 ? -79.651 -40.499 -29.581 1.00 101.80 ? 299 TRP B C 1 ATOM 6645 O O . TRP B 2 288 ? -80.222 -41.555 -29.859 1.00 97.41 ? 299 TRP B O 1 ATOM 6646 C CB . TRP B 2 288 ? -78.806 -40.186 -27.252 1.00 102.73 ? 299 TRP B CB 1 ATOM 6647 C CG . TRP B 2 288 ? -79.016 -41.548 -26.679 1.00 93.65 ? 299 TRP B CG 1 ATOM 6648 C CD1 . TRP B 2 288 ? -79.758 -41.872 -25.579 1.00 96.99 ? 299 TRP B CD1 1 ATOM 6649 C CD2 . TRP B 2 288 ? -78.490 -42.776 -27.187 1.00 84.41 ? 299 TRP B CD2 1 ATOM 6650 N NE1 . TRP B 2 288 ? -79.720 -43.228 -25.367 1.00 96.30 ? 299 TRP B NE1 1 ATOM 6651 C CE2 . TRP B 2 288 ? -78.947 -43.806 -26.340 1.00 85.54 ? 299 TRP B CE2 1 ATOM 6652 C CE3 . TRP B 2 288 ? -77.673 -43.105 -28.273 1.00 84.49 ? 299 TRP B CE3 1 ATOM 6653 C CZ2 . TRP B 2 288 ? -78.612 -45.141 -26.545 1.00 81.43 ? 299 TRP B CZ2 1 ATOM 6654 C CZ3 . TRP B 2 288 ? -77.344 -44.430 -28.475 1.00 81.88 ? 299 TRP B CZ3 1 ATOM 6655 C CH2 . TRP B 2 288 ? -77.813 -45.431 -27.616 1.00 76.83 ? 299 TRP B CH2 1 ATOM 6656 N N . GLU B 2 289 ? -78.783 -39.903 -30.396 1.00 105.22 ? 300 GLU B N 1 ATOM 6657 C CA . GLU B 2 289 ? -78.413 -40.458 -31.694 1.00 102.19 ? 300 GLU B CA 1 ATOM 6658 C C . GLU B 2 289 ? -77.286 -41.476 -31.571 1.00 101.86 ? 300 GLU B C 1 ATOM 6659 O O . GLU B 2 289 ? -76.302 -41.245 -30.866 1.00 101.05 ? 300 GLU B O 1 ATOM 6660 C CB . GLU B 2 289 ? -77.994 -39.344 -32.658 1.00 105.85 ? 300 GLU B CB 1 ATOM 6661 C CG . GLU B 2 289 ? -79.125 -38.445 -33.119 1.00 106.14 ? 300 GLU B CG 1 ATOM 6662 C CD . GLU B 2 289 ? -78.677 -37.442 -34.161 1.00 99.75 ? 300 GLU B CD 1 ATOM 6663 O OE1 . GLU B 2 289 ? -77.797 -36.615 -33.848 1.00 104.95 ? 300 GLU B OE1 1 ATOM 6664 O OE2 . GLU B 2 289 ? -79.194 -37.489 -35.298 1.00 89.77 ? 300 GLU B OE2 1 ATOM 6665 N N . SER B 2 290 ? -77.430 -42.595 -32.275 1.00 99.66 ? 301 SER B N 1 ATOM 6666 C CA . SER B 2 290 ? -76.434 -43.661 -32.259 1.00 100.66 ? 301 SER B CA 1 ATOM 6667 C C . SER B 2 290 ? -75.174 -43.262 -33.022 1.00 99.94 ? 301 SER B C 1 ATOM 6668 O O . SER B 2 290 ? -74.984 -42.094 -33.368 1.00 94.84 ? 301 SER B O 1 ATOM 6669 C CB . SER B 2 290 ? -77.013 -44.951 -32.857 1.00 92.57 ? 301 SER B CB 1 ATOM 6670 O OG . SER B 2 290 ? -76.789 -45.018 -34.255 1.00 85.23 ? 301 SER B OG 1 ATOM 6671 N N . ASP B 2 291 ? -74.314 -44.241 -33.279 1.00 100.32 ? 302 ASP B N 1 ATOM 6672 C CA . ASP B 2 291 ? -73.153 -44.033 -34.134 1.00 104.58 ? 302 ASP B CA 1 ATOM 6673 C C . ASP B 2 291 ? -73.458 -44.541 -35.541 1.00 108.64 ? 302 ASP B C 1 ATOM 6674 O O . ASP B 2 291 ? -73.991 -45.638 -35.713 1.00 103.58 ? 302 ASP B O 1 ATOM 6675 C CB . ASP B 2 291 ? -71.915 -44.723 -33.553 1.00 100.39 ? 302 ASP B CB 1 ATOM 6676 C CG . ASP B 2 291 ? -70.987 -43.753 -32.840 1.00 83.73 ? 302 ASP B CG 1 ATOM 6677 O OD1 . ASP B 2 291 ? -71.006 -42.551 -33.180 1.00 72.28 ? 302 ASP B OD1 1 ATOM 6678 O OD2 . ASP B 2 291 ? -70.232 -44.192 -31.945 1.00 78.62 ? 302 ASP B OD2 1 ATOM 6679 N N . ILE B 2 292 ? -73.129 -43.718 -36.536 1.00 108.06 ? 303 ILE B N 1 ATOM 6680 C CA . ILE B 2 292 ? -73.448 -43.985 -37.936 1.00 91.57 ? 303 ILE B CA 1 ATOM 6681 C C . ILE B 2 292 ? -72.829 -45.291 -38.421 1.00 89.99 ? 303 ILE B C 1 ATOM 6682 O O . ILE B 2 292 ? -71.629 -45.362 -38.687 1.00 86.95 ? 303 ILE B O 1 ATOM 6683 C CB . ILE B 2 292 ? -72.970 -42.824 -38.849 1.00 79.11 ? 303 ILE B CB 1 ATOM 6684 C CG1 . ILE B 2 292 ? -73.535 -41.485 -38.356 1.00 77.43 ? 303 ILE B CG1 1 ATOM 6685 C CG2 . ILE B 2 292 ? -73.365 -43.080 -40.296 1.00 81.62 ? 303 ILE B CG2 1 ATOM 6686 C CD1 . ILE B 2 292 ? -72.844 -40.259 -38.934 1.00 63.18 ? 303 ILE B CD1 1 ATOM 6687 N N . ARG B 2 293 ? -73.652 -46.331 -38.512 1.00 91.98 ? 304 ARG B N 1 ATOM 6688 C CA . ARG B 2 293 ? -73.210 -47.601 -39.074 1.00 98.21 ? 304 ARG B CA 1 ATOM 6689 C C . ARG B 2 293 ? -73.210 -47.529 -40.595 1.00 98.28 ? 304 ARG B C 1 ATOM 6690 O O . ARG B 2 293 ? -74.111 -46.947 -41.200 1.00 100.39 ? 304 ARG B O 1 ATOM 6691 C CB . ARG B 2 293 ? -74.099 -48.758 -38.597 1.00 96.80 ? 304 ARG B CB 1 ATOM 6692 C CG . ARG B 2 293 ? -73.868 -49.178 -37.154 1.00 97.08 ? 304 ARG B CG 1 ATOM 6693 C CD . ARG B 2 293 ? -74.959 -48.640 -36.247 1.00 103.70 ? 304 ARG B CD 1 ATOM 6694 N NE . ARG B 2 293 ? -76.286 -49.018 -36.724 1.00 117.25 ? 304 ARG B NE 1 ATOM 6695 C CZ . ARG B 2 293 ? -77.426 -48.684 -36.127 1.00 120.38 ? 304 ARG B CZ 1 ATOM 6696 N NH1 . ARG B 2 293 ? -77.412 -47.959 -35.017 1.00 114.59 ? 304 ARG B NH1 1 ATOM 6697 N NH2 . ARG B 2 293 ? -78.582 -49.077 -36.645 1.00 120.27 ? 304 ARG B NH2 1 ATOM 6698 N N . ILE B 2 294 ? -72.182 -48.107 -41.206 1.00 96.50 ? 305 ILE B N 1 ATOM 6699 C CA . ILE B 2 294 ? -72.126 -48.255 -42.653 1.00 94.75 ? 305 ILE B CA 1 ATOM 6700 C C . ILE B 2 294 ? -72.623 -49.649 -43.012 1.00 99.69 ? 305 ILE B C 1 ATOM 6701 O O . ILE B 2 294 ? -71.982 -50.649 -42.685 1.00 107.24 ? 305 ILE B O 1 ATOM 6702 C CB . ILE B 2 294 ? -70.698 -48.047 -43.206 1.00 96.53 ? 305 ILE B CB 1 ATOM 6703 C CG1 . ILE B 2 294 ? -70.124 -46.697 -42.752 1.00 96.79 ? 305 ILE B CG1 1 ATOM 6704 C CG2 . ILE B 2 294 ? -70.690 -48.166 -44.725 1.00 99.44 ? 305 ILE B CG2 1 ATOM 6705 C CD1 . ILE B 2 294 ? -69.262 -46.769 -41.494 1.00 93.05 ? 305 ILE B CD1 1 ATOM 6706 N N . LEU B 2 295 ? -73.774 -49.713 -43.672 1.00 99.30 ? 306 LEU B N 1 ATOM 6707 C CA . LEU B 2 295 ? -74.417 -50.989 -43.968 1.00 105.17 ? 306 LEU B CA 1 ATOM 6708 C C . LEU B 2 295 ? -73.881 -51.597 -45.257 1.00 109.79 ? 306 LEU B C 1 ATOM 6709 O O . LEU B 2 295 ? -73.645 -52.804 -45.334 1.00 116.80 ? 306 LEU B O 1 ATOM 6710 C CB . LEU B 2 295 ? -75.934 -50.815 -44.065 1.00 107.48 ? 306 LEU B CB 1 ATOM 6711 C CG . LEU B 2 295 ? -76.579 -49.951 -42.984 1.00 106.99 ? 306 LEU B CG 1 ATOM 6712 C CD1 . LEU B 2 295 ? -78.087 -49.954 -43.155 1.00 105.16 ? 306 LEU B CD1 1 ATOM 6713 C CD2 . LEU B 2 295 ? -76.184 -50.420 -41.587 1.00 110.34 ? 306 LEU B CD2 1 ATOM 6714 N N . LYS B 2 296 ? -73.694 -50.756 -46.268 1.00 111.50 ? 307 LYS B N 1 ATOM 6715 C CA . LYS B 2 296 ? -73.201 -51.226 -47.556 1.00 116.21 ? 307 LYS B CA 1 ATOM 6716 C C . LYS B 2 296 ? -72.223 -50.252 -48.195 1.00 121.93 ? 307 LYS B C 1 ATOM 6717 O O . LYS B 2 296 ? -72.546 -49.092 -48.437 1.00 119.27 ? 307 LYS B O 1 ATOM 6718 C CB . LYS B 2 296 ? -74.370 -51.503 -48.497 1.00 100.11 ? 307 LYS B CB 1 ATOM 6719 C CG . LYS B 2 296 ? -74.653 -52.986 -48.630 1.00 103.61 ? 307 LYS B CG 1 ATOM 6720 C CD . LYS B 2 296 ? -76.107 -53.278 -48.926 1.00 106.62 ? 307 LYS B CD 1 ATOM 6721 C CE . LYS B 2 296 ? -76.322 -54.775 -49.101 1.00 104.12 ? 307 LYS B CE 1 ATOM 6722 N NZ . LYS B 2 296 ? -75.390 -55.347 -50.115 1.00 111.21 ? 307 LYS B NZ 1 ATOM 6723 N N . GLU B 2 297 ? -71.021 -50.746 -48.470 1.00 130.29 ? 308 GLU B N 1 ATOM 6724 C CA . GLU B 2 297 ? -69.937 -49.924 -48.987 1.00 128.24 ? 308 GLU B CA 1 ATOM 6725 C C . GLU B 2 297 ? -69.421 -50.516 -50.296 1.00 120.36 ? 308 GLU B C 1 ATOM 6726 O O . GLU B 2 297 ? -69.036 -51.686 -50.344 1.00 109.88 ? 308 GLU B O 1 ATOM 6727 C CB . GLU B 2 297 ? -68.819 -49.820 -47.943 1.00 134.79 ? 308 GLU B CB 1 ATOM 6728 C CG . GLU B 2 297 ? -67.787 -48.745 -48.215 1.00 138.82 ? 308 GLU B CG 1 ATOM 6729 C CD . GLU B 2 297 ? -66.634 -49.246 -49.061 1.00 156.95 ? 308 GLU B CD 1 ATOM 6730 O OE1 . GLU B 2 297 ? -66.195 -50.397 -48.847 1.00 155.12 ? 308 GLU B OE1 1 ATOM 6731 O OE2 . GLU B 2 297 ? -66.173 -48.490 -49.942 1.00 160.04 ? 308 GLU B OE2 1 ATOM 6732 N N . HIS B 2 298 ? -69.420 -49.710 -51.356 1.00 119.68 ? 309 HIS B N 1 ATOM 6733 C CA . HIS B 2 298 ? -69.060 -50.205 -52.683 1.00 123.29 ? 309 HIS B CA 1 ATOM 6734 C C . HIS B 2 298 ? -68.677 -49.102 -53.678 1.00 111.85 ? 309 HIS B C 1 ATOM 6735 O O . HIS B 2 298 ? -69.541 -48.487 -54.304 1.00 107.54 ? 309 HIS B O 1 ATOM 6736 C CB . HIS B 2 298 ? -70.216 -51.032 -53.255 1.00 130.51 ? 309 HIS B CB 1 ATOM 6737 C CG . HIS B 2 298 ? -69.818 -51.938 -54.378 1.00 119.08 ? 309 HIS B CG 1 ATOM 6738 N ND1 . HIS B 2 298 ? -68.989 -53.024 -54.201 1.00 111.29 ? 309 HIS B ND1 1 ATOM 6739 C CD2 . HIS B 2 298 ? -70.141 -51.922 -55.692 1.00 109.92 ? 309 HIS B CD2 1 ATOM 6740 C CE1 . HIS B 2 298 ? -68.817 -53.638 -55.358 1.00 106.47 ? 309 HIS B CE1 1 ATOM 6741 N NE2 . HIS B 2 298 ? -69.505 -52.988 -56.280 1.00 111.36 ? 309 HIS B NE2 1 ATOM 6742 N N . LEU B 2 299 ? -67.368 -48.882 -53.808 1.00 109.58 ? 310 LEU B N 1 ATOM 6743 C CA . LEU B 2 299 ? -66.739 -48.050 -54.852 1.00 106.70 ? 310 LEU B CA 1 ATOM 6744 C C . LEU B 2 299 ? -67.505 -46.834 -55.400 1.00 101.44 ? 310 LEU B C 1 ATOM 6745 O O . LEU B 2 299 ? -67.973 -46.867 -56.535 1.00 94.68 ? 310 LEU B O 1 ATOM 6746 C CB . LEU B 2 299 ? -66.364 -48.947 -56.047 1.00 108.14 ? 310 LEU B CB 1 ATOM 6747 C CG . LEU B 2 299 ? -67.324 -50.043 -56.542 1.00 103.60 ? 310 LEU B CG 1 ATOM 6748 C CD1 . LEU B 2 299 ? -68.074 -49.643 -57.811 1.00 90.31 ? 310 LEU B CD1 1 ATOM 6749 C CD2 . LEU B 2 299 ? -66.598 -51.371 -56.749 1.00 108.98 ? 310 LEU B CD2 1 ATOM 6750 N N . GLY B 2 300 ? -67.638 -45.762 -54.620 1.00 104.64 ? 311 GLY B N 1 ATOM 6751 C CA . GLY B 2 300 ? -67.308 -45.718 -53.208 1.00 101.46 ? 311 GLY B CA 1 ATOM 6752 C C . GLY B 2 300 ? -68.559 -45.180 -52.546 1.00 96.92 ? 311 GLY B C 1 ATOM 6753 O O . GLY B 2 300 ? -68.516 -44.381 -51.609 1.00 97.59 ? 311 GLY B O 1 ATOM 6754 N N . GLU B 2 301 ? -69.689 -45.626 -53.082 1.00 91.97 ? 312 GLU B N 1 ATOM 6755 C CA . GLU B 2 301 ? -71.004 -45.169 -52.667 1.00 92.11 ? 312 GLU B CA 1 ATOM 6756 C C . GLU B 2 301 ? -71.524 -46.024 -51.521 1.00 96.91 ? 312 GLU B C 1 ATOM 6757 O O . GLU B 2 301 ? -71.306 -47.236 -51.494 1.00 101.88 ? 312 GLU B O 1 ATOM 6758 C CB . GLU B 2 301 ? -71.962 -45.209 -53.858 1.00 95.16 ? 312 GLU B CB 1 ATOM 6759 C CG . GLU B 2 301 ? -71.434 -44.457 -55.075 1.00 91.07 ? 312 GLU B CG 1 ATOM 6760 C CD . GLU B 2 301 ? -72.054 -44.922 -56.382 1.00 91.90 ? 312 GLU B CD 1 ATOM 6761 O OE1 . GLU B 2 301 ? -72.193 -46.148 -56.578 1.00 98.09 ? 312 GLU B OE1 1 ATOM 6762 O OE2 . GLU B 2 301 ? -72.406 -44.058 -57.214 1.00 81.03 ? 312 GLU B OE2 1 ATOM 6763 N N . GLN B 2 302 ? -72.216 -45.393 -50.579 1.00 93.28 ? 313 GLN B N 1 ATOM 6764 C CA . GLN B 2 302 ? -72.577 -46.063 -49.339 1.00 91.02 ? 313 GLN B CA 1 ATOM 6765 C C . GLN B 2 302 ? -74.069 -46.113 -49.057 1.00 85.78 ? 313 GLN B C 1 ATOM 6766 O O . GLN B 2 302 ? -74.847 -45.303 -49.561 1.00 86.04 ? 313 GLN B O 1 ATOM 6767 C CB . GLN B 2 302 ? -71.877 -45.387 -48.159 1.00 94.43 ? 313 GLN B CB 1 ATOM 6768 C CG . GLN B 2 302 ? -70.426 -45.780 -47.989 1.00 97.86 ? 313 GLN B CG 1 ATOM 6769 C CD . GLN B 2 302 ? -69.740 -44.983 -46.904 1.00 101.28 ? 313 GLN B CD 1 ATOM 6770 O OE1 . GLN B 2 302 ? -69.865 -43.759 -46.845 1.00 105.39 ? 313 GLN B OE1 1 ATOM 6771 N NE2 . GLN B 2 302 ? -69.018 -45.673 -46.029 1.00 103.23 ? 313 GLN B NE2 1 ATOM 6772 N N . GLU B 2 303 ? -74.449 -47.090 -48.244 1.00 87.85 ? 314 GLU B N 1 ATOM 6773 C CA . GLU B 2 303 ? -75.769 -47.137 -47.639 1.00 93.72 ? 314 GLU B CA 1 ATOM 6774 C C . GLU B 2 303 ? -75.576 -47.115 -46.126 1.00 103.71 ? 314 GLU B C 1 ATOM 6775 O O . GLU B 2 303 ? -75.218 -48.129 -45.526 1.00 108.34 ? 314 GLU B O 1 ATOM 6776 C CB . GLU B 2 303 ? -76.537 -48.383 -48.082 1.00 97.87 ? 314 GLU B CB 1 ATOM 6777 C CG . GLU B 2 303 ? -77.943 -48.479 -47.511 1.00 101.68 ? 314 GLU B CG 1 ATOM 6778 C CD . GLU B 2 303 ? -78.708 -49.673 -48.044 1.00 96.54 ? 314 GLU B CD 1 ATOM 6779 O OE1 . GLU B 2 303 ? -78.359 -50.159 -49.140 1.00 99.95 ? 314 GLU B OE1 1 ATOM 6780 O OE2 . GLU B 2 303 ? -79.653 -50.133 -47.367 1.00 88.59 ? 314 GLU B OE2 1 ATOM 6781 N N . VAL B 2 304 ? -75.785 -45.951 -45.516 1.00 99.63 ? 315 VAL B N 1 ATOM 6782 C CA . VAL B 2 304 ? -75.504 -45.765 -44.095 1.00 97.80 ? 315 VAL B CA 1 ATOM 6783 C C . VAL B 2 304 ? -76.767 -45.844 -43.242 1.00 98.18 ? 315 VAL B C 1 ATOM 6784 O O . VAL B 2 304 ? -77.886 -45.813 -43.759 1.00 94.35 ? 315 VAL B O 1 ATOM 6785 C CB . VAL B 2 304 ? -74.796 -44.409 -43.826 1.00 88.62 ? 315 VAL B CB 1 ATOM 6786 C CG1 . VAL B 2 304 ? -73.309 -44.505 -44.159 1.00 88.05 ? 315 VAL B CG1 1 ATOM 6787 C CG2 . VAL B 2 304 ? -75.464 -43.280 -44.605 1.00 84.26 ? 315 VAL B CG2 1 ATOM 6788 N N . SER B 2 305 ? -76.575 -45.959 -41.932 1.00 101.28 ? 316 SER B N 1 ATOM 6789 C CA . SER B 2 305 ? -77.683 -46.023 -40.989 1.00 92.91 ? 316 SER B CA 1 ATOM 6790 C C . SER B 2 305 ? -77.348 -45.320 -39.679 1.00 89.79 ? 316 SER B C 1 ATOM 6791 O O . SER B 2 305 ? -76.285 -45.530 -39.092 1.00 90.19 ? 316 SER B O 1 ATOM 6792 C CB . SER B 2 305 ? -78.072 -47.475 -40.710 1.00 90.90 ? 316 SER B CB 1 ATOM 6793 O OG . SER B 2 305 ? -79.047 -47.551 -39.688 1.00 95.55 ? 316 SER B OG 1 ATOM 6794 N N . ILE B 2 306 ? -78.266 -44.468 -39.238 1.00 82.22 ? 317 ILE B N 1 ATOM 6795 C CA . ILE B 2 306 ? -78.196 -43.853 -37.923 1.00 82.48 ? 317 ILE B CA 1 ATOM 6796 C C . ILE B 2 306 ? -79.600 -43.871 -37.320 1.00 84.09 ? 317 ILE B C 1 ATOM 6797 O O . ILE B 2 306 ? -80.587 -43.570 -37.997 1.00 78.37 ? 317 ILE B O 1 ATOM 6798 C CB . ILE B 2 306 ? -77.637 -42.412 -37.983 1.00 80.92 ? 317 ILE B CB 1 ATOM 6799 C CG1 . ILE B 2 306 ? -77.731 -41.742 -36.608 1.00 84.57 ? 317 ILE B CG1 1 ATOM 6800 C CG2 . ILE B 2 306 ? -78.359 -41.594 -39.044 1.00 77.83 ? 317 ILE B CG2 1 ATOM 6801 C CD1 . ILE B 2 306 ? -77.232 -40.317 -36.579 1.00 86.78 ? 317 ILE B CD1 1 ATOM 6802 N N . SER B 2 307 ? -79.688 -44.255 -36.051 1.00 94.82 ? 318 SER B N 1 ATOM 6803 C CA . SER B 2 307 ? -80.975 -44.460 -35.400 1.00 94.73 ? 318 SER B CA 1 ATOM 6804 C C . SER B 2 307 ? -81.196 -43.521 -34.213 1.00 91.02 ? 318 SER B C 1 ATOM 6805 O O . SER B 2 307 ? -80.264 -43.188 -33.479 1.00 92.21 ? 318 SER B O 1 ATOM 6806 C CB . SER B 2 307 ? -81.107 -45.922 -34.947 1.00 93.40 ? 318 SER B CB 1 ATOM 6807 O OG . SER B 2 307 ? -79.888 -46.429 -34.432 1.00 93.49 ? 318 SER B OG 1 ATOM 6808 N N . LEU B 2 308 ? -82.438 -43.083 -34.041 1.00 79.73 ? 319 LEU B N 1 ATOM 6809 C CA . LEU B 2 308 ? -82.826 -42.351 -32.847 1.00 66.96 ? 319 LEU B CA 1 ATOM 6810 C C . LEU B 2 308 ? -83.115 -43.357 -31.739 1.00 76.18 ? 319 LEU B C 1 ATOM 6811 O O . LEU B 2 308 ? -83.657 -44.433 -31.998 1.00 75.36 ? 319 LEU B O 1 ATOM 6812 C CB . LEU B 2 308 ? -84.053 -41.476 -33.111 1.00 59.18 ? 319 LEU B CB 1 ATOM 6813 C CG . LEU B 2 308 ? -84.050 -40.036 -32.591 1.00 57.00 ? 319 LEU B CG 1 ATOM 6814 C CD1 . LEU B 2 308 ? -85.477 -39.559 -32.359 1.00 55.05 ? 319 LEU B CD1 1 ATOM 6815 C CD2 . LEU B 2 308 ? -83.211 -39.883 -31.331 1.00 73.12 ? 319 LEU B CD2 1 ATOM 6816 N N . ILE B 2 309 ? -82.748 -43.011 -30.509 1.00 86.77 ? 320 ILE B N 1 ATOM 6817 C CA . ILE B 2 309 ? -83.004 -43.875 -29.361 1.00 90.07 ? 320 ILE B CA 1 ATOM 6818 C C . ILE B 2 309 ? -83.666 -43.111 -28.215 1.00 87.68 ? 320 ILE B C 1 ATOM 6819 O O . ILE B 2 309 ? -83.082 -42.189 -27.651 1.00 86.63 ? 320 ILE B O 1 ATOM 6820 C CB . ILE B 2 309 ? -81.704 -44.535 -28.843 1.00 89.79 ? 320 ILE B CB 1 ATOM 6821 C CG1 . ILE B 2 309 ? -81.159 -45.532 -29.869 1.00 87.25 ? 320 ILE B CG1 1 ATOM 6822 C CG2 . ILE B 2 309 ? -81.953 -45.235 -27.519 1.00 95.61 ? 320 ILE B CG2 1 ATOM 6823 C CD1 . ILE B 2 309 ? -82.110 -46.664 -30.184 1.00 86.60 ? 320 ILE B CD1 1 ATOM 6824 N N . VAL B 2 310 ? -84.894 -43.500 -27.881 1.00 81.59 ? 321 VAL B N 1 ATOM 6825 C CA . VAL B 2 310 ? -85.605 -42.941 -26.735 1.00 91.60 ? 321 VAL B CA 1 ATOM 6826 C C . VAL B 2 310 ? -85.728 -44.010 -25.646 1.00 106.70 ? 321 VAL B C 1 ATOM 6827 O O . VAL B 2 310 ? -86.294 -45.075 -25.880 1.00 105.82 ? 321 VAL B O 1 ATOM 6828 C CB . VAL B 2 310 ? -87.004 -42.417 -27.141 1.00 84.69 ? 321 VAL B CB 1 ATOM 6829 C CG1 . VAL B 2 310 ? -87.753 -41.869 -25.935 1.00 101.80 ? 321 VAL B CG1 1 ATOM 6830 C CG2 . VAL B 2 310 ? -86.885 -41.349 -28.213 1.00 78.29 ? 321 VAL B CG2 1 ATOM 6831 N N . ASP B 2 311 ? -85.185 -43.725 -24.465 1.00 105.33 ? 322 ASP B N 1 ATOM 6832 C CA . ASP B 2 311 ? -85.220 -44.664 -23.349 1.00 87.18 ? 322 ASP B CA 1 ATOM 6833 C C . ASP B 2 311 ? -86.595 -44.714 -22.697 1.00 85.36 ? 322 ASP B C 1 ATOM 6834 O O . ASP B 2 311 ? -87.363 -45.646 -22.927 1.00 77.59 ? 322 ASP B O 1 ATOM 6835 C CB . ASP B 2 311 ? -84.158 -44.296 -22.313 1.00 89.36 ? 322 ASP B CB 1 ATOM 6836 C CG . ASP B 2 311 ? -82.763 -44.671 -22.759 1.00 98.18 ? 322 ASP B CG 1 ATOM 6837 O OD1 . ASP B 2 311 ? -82.636 -45.662 -23.511 1.00 87.65 ? 322 ASP B OD1 1 ATOM 6838 O OD2 . ASP B 2 311 ? -81.801 -43.982 -22.359 1.00 110.16 ? 322 ASP B OD2 1 ATOM 6839 N N . SER B 2 312 ? -86.901 -43.710 -21.882 1.00 84.66 ? 323 SER B N 1 ATOM 6840 C CA . SER B 2 312 ? -88.207 -43.624 -21.238 1.00 92.15 ? 323 SER B CA 1 ATOM 6841 C C . SER B 2 312 ? -89.122 -42.721 -22.063 1.00 92.77 ? 323 SER B C 1 ATOM 6842 O O . SER B 2 312 ? -88.955 -41.500 -22.078 1.00 93.56 ? 323 SER B O 1 ATOM 6843 C CB . SER B 2 312 ? -88.071 -43.107 -19.800 1.00 97.03 ? 323 SER B CB 1 ATOM 6844 O OG . SER B 2 312 ? -89.245 -43.351 -19.038 1.00 89.44 ? 323 SER B OG 1 ATOM 6845 N N . VAL B 2 313 ? -90.082 -43.329 -22.758 1.00 84.78 ? 324 VAL B N 1 ATOM 6846 C CA . VAL B 2 313 ? -90.965 -42.596 -23.664 1.00 81.95 ? 324 VAL B CA 1 ATOM 6847 C C . VAL B 2 313 ? -92.038 -41.824 -22.901 1.00 90.52 ? 324 VAL B C 1 ATOM 6848 O O . VAL B 2 313 ? -93.013 -42.401 -22.415 1.00 92.84 ? 324 VAL B O 1 ATOM 6849 C CB . VAL B 2 313 ? -91.646 -43.540 -24.687 1.00 78.12 ? 324 VAL B CB 1 ATOM 6850 C CG1 . VAL B 2 313 ? -92.655 -42.779 -25.542 1.00 87.52 ? 324 VAL B CG1 1 ATOM 6851 C CG2 . VAL B 2 313 ? -90.604 -44.195 -25.573 1.00 79.55 ? 324 VAL B CG2 1 ATOM 6852 N N . GLU B 2 314 ? -91.841 -40.513 -22.796 1.00 98.65 ? 325 GLU B N 1 ATOM 6853 C CA . GLU B 2 314 ? -92.819 -39.628 -22.174 1.00 102.31 ? 325 GLU B CA 1 ATOM 6854 C C . GLU B 2 314 ? -93.877 -39.198 -23.179 1.00 103.30 ? 325 GLU B C 1 ATOM 6855 O O . GLU B 2 314 ? -94.130 -39.889 -24.166 1.00 101.18 ? 325 GLU B O 1 ATOM 6856 C CB . GLU B 2 314 ? -92.139 -38.393 -21.579 1.00 102.92 ? 325 GLU B CB 1 ATOM 6857 C CG . GLU B 2 314 ? -91.309 -38.665 -20.342 1.00 104.86 ? 325 GLU B CG 1 ATOM 6858 C CD . GLU B 2 314 ? -90.721 -37.395 -19.763 1.00 109.80 ? 325 GLU B CD 1 ATOM 6859 O OE1 . GLU B 2 314 ? -91.334 -36.324 -19.953 1.00 110.02 ? 325 GLU B OE1 1 ATOM 6860 O OE2 . GLU B 2 314 ? -89.645 -37.465 -19.131 1.00 115.95 ? 325 GLU B OE2 1 ATOM 6861 N N . GLU B 2 315 ? -94.476 -38.039 -22.925 1.00 108.06 ? 326 GLU B N 1 ATOM 6862 C CA . GLU B 2 315 ? -95.595 -37.542 -23.726 1.00 116.64 ? 326 GLU B CA 1 ATOM 6863 C C . GLU B 2 315 ? -95.442 -36.276 -24.620 1.00 123.79 ? 326 GLU B C 1 ATOM 6864 O O . GLU B 2 315 ? -96.341 -36.033 -25.424 1.00 136.41 ? 326 GLU B O 1 ATOM 6865 C CB . GLU B 2 315 ? -96.782 -37.295 -22.786 1.00 121.36 ? 326 GLU B CB 1 ATOM 6866 C CG . GLU B 2 315 ? -97.598 -38.535 -22.430 1.00 114.12 ? 326 GLU B CG 1 ATOM 6867 C CD . GLU B 2 315 ? -98.788 -38.737 -23.353 1.00 111.09 ? 326 GLU B CD 1 ATOM 6868 O OE1 . GLU B 2 315 ? -98.819 -38.111 -24.434 1.00 109.91 ? 326 GLU B OE1 1 ATOM 6869 O OE2 . GLU B 2 315 ? -99.700 -39.514 -22.994 1.00 114.33 ? 326 GLU B OE2 1 ATOM 6870 N N . GLY B 2 316 ? -94.371 -35.472 -24.549 1.00 117.14 ? 327 GLY B N 1 ATOM 6871 C CA . GLY B 2 316 ? -93.131 -35.711 -23.832 1.00 110.36 ? 327 GLY B CA 1 ATOM 6872 C C . GLY B 2 316 ? -92.021 -35.944 -24.837 1.00 107.82 ? 327 GLY B C 1 ATOM 6873 O O . GLY B 2 316 ? -91.004 -35.249 -24.830 1.00 109.16 ? 327 GLY B O 1 ATOM 6874 N N . ASP B 2 317 ? -92.230 -36.930 -25.707 1.00 105.20 ? 328 ASP B N 1 ATOM 6875 C CA . ASP B 2 317 ? -91.324 -37.207 -26.818 1.00 106.42 ? 328 ASP B CA 1 ATOM 6876 C C . ASP B 2 317 ? -92.097 -37.350 -28.123 1.00 101.32 ? 328 ASP B C 1 ATOM 6877 O O . ASP B 2 317 ? -91.584 -37.046 -29.199 1.00 98.13 ? 328 ASP B O 1 ATOM 6878 C CB . ASP B 2 317 ? -90.513 -38.480 -26.562 1.00 102.41 ? 328 ASP B CB 1 ATOM 6879 C CG . ASP B 2 317 ? -89.539 -38.332 -25.417 1.00 95.43 ? 328 ASP B CG 1 ATOM 6880 O OD1 . ASP B 2 317 ? -88.568 -37.557 -25.558 1.00 91.07 ? 328 ASP B OD1 1 ATOM 6881 O OD2 . ASP B 2 317 ? -89.739 -38.998 -24.380 1.00 96.50 ? 328 ASP B OD2 1 ATOM 6882 N N . LEU B 2 318 ? -93.337 -37.816 -28.004 1.00 98.12 ? 329 LEU B N 1 ATOM 6883 C CA . LEU B 2 318 ? -94.197 -38.136 -29.142 1.00 94.67 ? 329 LEU B CA 1 ATOM 6884 C C . LEU B 2 318 ? -94.229 -37.079 -30.242 1.00 90.86 ? 329 LEU B C 1 ATOM 6885 O O . LEU B 2 318 ? -94.102 -35.881 -29.981 1.00 83.31 ? 329 LEU B O 1 ATOM 6886 C CB . LEU B 2 318 ? -95.625 -38.370 -28.652 1.00 99.84 ? 329 LEU B CB 1 ATOM 6887 C CG . LEU B 2 318 ? -95.787 -39.273 -27.429 1.00 99.68 ? 329 LEU B CG 1 ATOM 6888 C CD1 . LEU B 2 318 ? -97.224 -39.227 -26.950 1.00 100.58 ? 329 LEU B CD1 1 ATOM 6889 C CD2 . LEU B 2 318 ? -95.355 -40.703 -27.737 1.00 91.73 ? 329 LEU B CD2 1 ATOM 6890 N N . GLY B 2 319 ? -94.402 -37.539 -31.477 1.00 96.38 ? 330 GLY B N 1 ATOM 6891 C CA . GLY B 2 319 ? -94.689 -36.646 -32.581 1.00 107.54 ? 330 GLY B CA 1 ATOM 6892 C C . GLY B 2 319 ? -93.733 -36.645 -33.756 1.00 99.03 ? 330 GLY B C 1 ATOM 6893 O O . GLY B 2 319 ? -93.474 -37.677 -34.382 1.00 88.11 ? 330 GLY B O 1 ATOM 6894 N N . ASN B 2 320 ? -93.213 -35.460 -34.055 1.00 93.13 ? 331 ASN B N 1 ATOM 6895 C CA . ASN B 2 320 ? -92.458 -35.235 -35.276 1.00 78.32 ? 331 ASN B CA 1 ATOM 6896 C C . ASN B 2 320 ? -90.951 -35.393 -35.123 1.00 76.97 ? 331 ASN B C 1 ATOM 6897 O O . ASN B 2 320 ? -90.287 -34.596 -34.457 1.00 80.00 ? 331 ASN B O 1 ATOM 6898 C CB . ASN B 2 320 ? -92.777 -33.843 -35.824 1.00 85.77 ? 331 ASN B CB 1 ATOM 6899 C CG . ASN B 2 320 ? -94.069 -33.815 -36.617 1.00 97.69 ? 331 ASN B CG 1 ATOM 6900 O OD1 . ASN B 2 320 ? -94.412 -34.783 -37.295 1.00 107.08 ? 331 ASN B OD1 1 ATOM 6901 N ND2 . ASN B 2 320 ? -94.794 -32.705 -36.534 1.00 91.47 ? 331 ASN B ND2 1 ATOM 6902 N N . TYR B 2 321 ? -90.425 -36.443 -35.744 1.00 75.08 ? 332 TYR B N 1 ATOM 6903 C CA . TYR B 2 321 ? -88.987 -36.624 -35.886 1.00 79.60 ? 332 TYR B CA 1 ATOM 6904 C C . TYR B 2 321 ? -88.634 -36.781 -37.358 1.00 78.71 ? 332 TYR B C 1 ATOM 6905 O O . TYR B 2 321 ? -89.110 -37.696 -38.031 1.00 73.90 ? 332 TYR B O 1 ATOM 6906 C CB . TYR B 2 321 ? -88.496 -37.831 -35.080 1.00 84.41 ? 332 TYR B CB 1 ATOM 6907 C CG . TYR B 2 321 ? -88.589 -37.635 -33.585 1.00 83.23 ? 332 TYR B CG 1 ATOM 6908 C CD1 . TYR B 2 321 ? -87.659 -36.852 -32.908 1.00 77.02 ? 332 TYR B CD1 1 ATOM 6909 C CD2 . TYR B 2 321 ? -89.612 -38.219 -32.852 1.00 90.75 ? 332 TYR B CD2 1 ATOM 6910 C CE1 . TYR B 2 321 ? -87.742 -36.664 -31.544 1.00 87.86 ? 332 TYR B CE1 1 ATOM 6911 C CE2 . TYR B 2 321 ? -89.706 -38.037 -31.486 1.00 95.78 ? 332 TYR B CE2 1 ATOM 6912 C CZ . TYR B 2 321 ? -88.770 -37.260 -30.837 1.00 100.39 ? 332 TYR B CZ 1 ATOM 6913 O OH . TYR B 2 321 ? -88.863 -37.079 -29.477 1.00 111.40 ? 332 TYR B OH 1 ATOM 6914 N N . SER B 2 322 ? -87.809 -35.865 -37.853 1.00 83.43 ? 333 SER B N 1 ATOM 6915 C CA . SER B 2 322 ? -87.395 -35.874 -39.248 1.00 79.42 ? 333 SER B CA 1 ATOM 6916 C C . SER B 2 322 ? -85.919 -36.244 -39.391 1.00 80.84 ? 333 SER B C 1 ATOM 6917 O O . SER B 2 322 ? -85.055 -35.685 -38.713 1.00 78.72 ? 333 SER B O 1 ATOM 6918 C CB . SER B 2 322 ? -87.675 -34.512 -39.902 1.00 74.08 ? 333 SER B CB 1 ATOM 6919 O OG . SER B 2 322 ? -87.627 -33.456 -38.960 1.00 74.00 ? 333 SER B OG 1 ATOM 6920 N N . CYS B 2 323 ? -85.648 -37.210 -40.264 1.00 81.25 ? 334 CYS B N 1 ATOM 6921 C CA . CYS B 2 323 ? -84.287 -37.583 -40.626 1.00 74.50 ? 334 CYS B CA 1 ATOM 6922 C C . CYS B 2 323 ? -83.775 -36.630 -41.691 1.00 72.84 ? 334 CYS B C 1 ATOM 6923 O O . CYS B 2 323 ? -84.479 -36.335 -42.654 1.00 76.18 ? 334 CYS B O 1 ATOM 6924 C CB . CYS B 2 323 ? -84.228 -39.030 -41.134 1.00 71.90 ? 334 CYS B CB 1 ATOM 6925 S SG . CYS B 2 323 ? -82.641 -39.508 -41.874 1.00 42.48 ? 334 CYS B SG 1 ATOM 6926 N N . TYR B 2 324 ? -82.553 -36.144 -41.514 1.00 73.62 ? 335 TYR B N 1 ATOM 6927 C CA . TYR B 2 324 ? -81.955 -35.231 -42.477 1.00 80.57 ? 335 TYR B CA 1 ATOM 6928 C C . TYR B 2 324 ? -80.747 -35.860 -43.162 1.00 86.59 ? 335 TYR B C 1 ATOM 6929 O O . TYR B 2 324 ? -79.887 -36.463 -42.515 1.00 79.98 ? 335 TYR B O 1 ATOM 6930 C CB . TYR B 2 324 ? -81.561 -33.921 -41.795 1.00 75.03 ? 335 TYR B CB 1 ATOM 6931 C CG . TYR B 2 324 ? -82.659 -32.882 -41.791 1.00 70.46 ? 335 TYR B CG 1 ATOM 6932 C CD1 . TYR B 2 324 ? -83.821 -33.073 -41.055 1.00 77.01 ? 335 TYR B CD1 1 ATOM 6933 C CD2 . TYR B 2 324 ? -82.532 -31.708 -42.524 1.00 70.89 ? 335 TYR B CD2 1 ATOM 6934 C CE1 . TYR B 2 324 ? -84.830 -32.128 -41.051 1.00 83.31 ? 335 TYR B CE1 1 ATOM 6935 C CE2 . TYR B 2 324 ? -83.533 -30.754 -42.526 1.00 80.68 ? 335 TYR B CE2 1 ATOM 6936 C CZ . TYR B 2 324 ? -84.682 -30.969 -41.787 1.00 85.41 ? 335 TYR B CZ 1 ATOM 6937 O OH . TYR B 2 324 ? -85.688 -30.029 -41.777 1.00 82.89 ? 335 TYR B OH 1 ATOM 6938 N N . VAL B 2 325 ? -80.699 -35.719 -44.482 1.00 90.18 ? 336 VAL B N 1 ATOM 6939 C CA . VAL B 2 325 ? -79.602 -36.242 -45.278 1.00 78.69 ? 336 VAL B CA 1 ATOM 6940 C C . VAL B 2 325 ? -79.070 -35.117 -46.167 1.00 77.83 ? 336 VAL B C 1 ATOM 6941 O O . VAL B 2 325 ? -79.821 -34.224 -46.578 1.00 72.94 ? 336 VAL B O 1 ATOM 6942 C CB . VAL B 2 325 ? -80.049 -37.463 -46.112 1.00 76.61 ? 336 VAL B CB 1 ATOM 6943 C CG1 . VAL B 2 325 ? -80.551 -37.047 -47.489 1.00 83.60 ? 336 VAL B CG1 1 ATOM 6944 C CG2 . VAL B 2 325 ? -78.925 -38.463 -46.226 1.00 82.80 ? 336 VAL B CG2 1 ATOM 6945 N N . GLU B 2 326 ? -77.769 -35.142 -46.439 1.00 87.37 ? 337 GLU B N 1 ATOM 6946 C CA . GLU B 2 326 ? -77.115 -34.008 -47.081 1.00 100.61 ? 337 GLU B CA 1 ATOM 6947 C C . GLU B 2 326 ? -75.678 -34.294 -47.511 1.00 105.19 ? 337 GLU B C 1 ATOM 6948 O O . GLU B 2 326 ? -74.918 -34.949 -46.796 1.00 102.93 ? 337 GLU B O 1 ATOM 6949 C CB . GLU B 2 326 ? -77.127 -32.802 -46.134 1.00 99.89 ? 337 GLU B CB 1 ATOM 6950 C CG . GLU B 2 326 ? -76.547 -31.526 -46.718 1.00 103.66 ? 337 GLU B CG 1 ATOM 6951 C CD . GLU B 2 326 ? -76.523 -30.389 -45.717 1.00 103.55 ? 337 GLU B CD 1 ATOM 6952 O OE1 . GLU B 2 326 ? -75.509 -30.247 -45.003 1.00 113.28 ? 337 GLU B OE1 1 ATOM 6953 O OE2 . GLU B 2 326 ? -77.520 -29.642 -45.638 1.00 93.63 ? 337 GLU B OE2 1 ATOM 6954 N N . ASN B 2 327 ? -75.320 -33.792 -48.690 1.00 106.20 ? 338 ASN B N 1 ATOM 6955 C CA . ASN B 2 327 ? -73.936 -33.750 -49.137 1.00 105.63 ? 338 ASN B CA 1 ATOM 6956 C C . ASN B 2 327 ? -73.649 -32.367 -49.717 1.00 115.12 ? 338 ASN B C 1 ATOM 6957 O O . ASN B 2 327 ? -74.296 -31.392 -49.336 1.00 114.62 ? 338 ASN B O 1 ATOM 6958 C CB . ASN B 2 327 ? -73.648 -34.859 -50.161 1.00 103.96 ? 338 ASN B CB 1 ATOM 6959 C CG . ASN B 2 327 ? -74.426 -34.692 -51.458 1.00 104.21 ? 338 ASN B CG 1 ATOM 6960 O OD1 . ASN B 2 327 ? -75.457 -34.020 -51.503 1.00 98.17 ? 338 ASN B OD1 1 ATOM 6961 N ND2 . ASN B 2 327 ? -73.931 -35.316 -52.523 1.00 104.33 ? 338 ASN B ND2 1 ATOM 6962 N N . GLY B 2 328 ? -72.693 -32.272 -50.634 1.00 125.83 ? 339 GLY B N 1 ATOM 6963 C CA . GLY B 2 328 ? -72.397 -31.002 -51.274 1.00 126.16 ? 339 GLY B CA 1 ATOM 6964 C C . GLY B 2 328 ? -73.258 -30.707 -52.491 1.00 115.80 ? 339 GLY B C 1 ATOM 6965 O O . GLY B 2 328 ? -72.808 -30.055 -53.435 1.00 106.54 ? 339 GLY B O 1 ATOM 6966 N N . ASN B 2 329 ? -74.502 -31.182 -52.471 1.00 109.15 ? 340 ASN B N 1 ATOM 6967 C CA . ASN B 2 329 ? -75.405 -31.019 -53.608 1.00 107.65 ? 340 ASN B CA 1 ATOM 6968 C C . ASN B 2 329 ? -76.837 -30.674 -53.201 1.00 111.84 ? 340 ASN B C 1 ATOM 6969 O O . ASN B 2 329 ? -77.720 -30.563 -54.050 1.00 121.35 ? 340 ASN B O 1 ATOM 6970 C CB . ASN B 2 329 ? -75.409 -32.290 -54.460 1.00 117.64 ? 340 ASN B CB 1 ATOM 6971 C CG . ASN B 2 329 ? -74.017 -32.695 -54.908 1.00 122.67 ? 340 ASN B CG 1 ATOM 6972 O OD1 . ASN B 2 329 ? -73.597 -33.836 -54.711 1.00 124.21 ? 340 ASN B OD1 1 ATOM 6973 N ND2 . ASN B 2 329 ? -73.292 -31.757 -55.508 1.00 122.10 ? 340 ASN B ND2 1 ATOM 6974 N N . GLY B 2 330 ? -77.063 -30.510 -51.902 1.00 107.07 ? 341 GLY B N 1 ATOM 6975 C CA . GLY B 2 330 ? -78.375 -30.143 -51.402 1.00 105.35 ? 341 GLY B CA 1 ATOM 6976 C C . GLY B 2 330 ? -78.712 -30.826 -50.093 1.00 99.12 ? 341 GLY B C 1 ATOM 6977 O O . GLY B 2 330 ? -77.911 -31.594 -49.563 1.00 96.35 ? 341 GLY B O 1 ATOM 6978 N N . ARG B 2 331 ? -79.905 -30.548 -49.578 1.00 97.32 ? 342 ARG B N 1 ATOM 6979 C CA . ARG B 2 331 ? -80.352 -31.112 -48.309 1.00 96.82 ? 342 ARG B CA 1 ATOM 6980 C C . ARG B 2 331 ? -81.757 -31.690 -48.422 1.00 95.10 ? 342 ARG B C 1 ATOM 6981 O O . ARG B 2 331 ? -82.718 -30.968 -48.694 1.00 95.76 ? 342 ARG B O 1 ATOM 6982 C CB . ARG B 2 331 ? -80.315 -30.048 -47.212 1.00 104.16 ? 342 ARG B CB 1 ATOM 6983 C CG . ARG B 2 331 ? -80.679 -30.553 -45.824 1.00 101.93 ? 342 ARG B CG 1 ATOM 6984 C CD . ARG B 2 331 ? -80.833 -29.397 -44.841 1.00 103.54 ? 342 ARG B CD 1 ATOM 6985 N NE . ARG B 2 331 ? -79.689 -28.489 -44.881 1.00 105.54 ? 342 ARG B NE 1 ATOM 6986 C CZ . ARG B 2 331 ? -79.753 -27.216 -45.258 1.00 99.69 ? 342 ARG B CZ 1 ATOM 6987 N NH1 . ARG B 2 331 ? -80.913 -26.688 -45.622 1.00 103.49 ? 342 ARG B NH1 1 ATOM 6988 N NH2 . ARG B 2 331 ? -78.656 -26.469 -45.264 1.00 88.43 ? 342 ARG B NH2 1 ATOM 6989 N N . ARG B 2 332 ? -81.868 -32.997 -48.209 1.00 92.71 ? 343 ARG B N 1 ATOM 6990 C CA . ARG B 2 332 ? -83.158 -33.672 -48.243 1.00 97.88 ? 343 ARG B CA 1 ATOM 6991 C C . ARG B 2 332 ? -83.502 -34.245 -46.872 1.00 90.29 ? 343 ARG B C 1 ATOM 6992 O O . ARG B 2 332 ? -82.635 -34.754 -46.161 1.00 87.13 ? 343 ARG B O 1 ATOM 6993 C CB . ARG B 2 332 ? -83.165 -34.779 -49.305 1.00 99.61 ? 343 ARG B CB 1 ATOM 6994 C CG . ARG B 2 332 ? -82.921 -34.282 -50.725 1.00 92.94 ? 343 ARG B CG 1 ATOM 6995 C CD . ARG B 2 332 ? -83.839 -33.124 -51.081 1.00 94.69 ? 343 ARG B CD 1 ATOM 6996 N NE . ARG B 2 332 ? -83.096 -31.974 -51.591 1.00 107.06 ? 343 ARG B NE 1 ATOM 6997 C CZ . ARG B 2 332 ? -82.645 -31.866 -52.837 1.00 111.58 ? 343 ARG B CZ 1 ATOM 6998 N NH1 . ARG B 2 332 ? -82.858 -32.843 -53.709 1.00 110.78 ? 343 ARG B NH1 1 ATOM 6999 N NH2 . ARG B 2 332 ? -81.978 -30.782 -53.210 1.00 110.69 ? 343 ARG B NH2 1 ATOM 7000 N N . HIS B 2 333 ? -84.773 -34.148 -46.503 1.00 84.02 ? 344 HIS B N 1 ATOM 7001 C CA . HIS B 2 333 ? -85.241 -34.677 -45.231 1.00 75.63 ? 344 HIS B CA 1 ATOM 7002 C C . HIS B 2 333 ? -86.497 -35.514 -45.423 1.00 76.36 ? 344 HIS B C 1 ATOM 7003 O O . HIS B 2 333 ? -87.285 -35.259 -46.331 1.00 74.63 ? 344 HIS B O 1 ATOM 7004 C CB . HIS B 2 333 ? -85.505 -33.538 -44.236 1.00 72.92 ? 344 HIS B CB 1 ATOM 7005 C CG . HIS B 2 333 ? -86.520 -32.537 -44.702 1.00 75.46 ? 344 HIS B CG 1 ATOM 7006 N ND1 . HIS B 2 333 ? -87.684 -32.892 -45.349 1.00 74.47 ? 344 HIS B ND1 1 ATOM 7007 C CD2 . HIS B 2 333 ? -86.548 -31.188 -44.596 1.00 83.53 ? 344 HIS B CD2 1 ATOM 7008 C CE1 . HIS B 2 333 ? -88.381 -31.806 -45.629 1.00 81.87 ? 344 HIS B CE1 1 ATOM 7009 N NE2 . HIS B 2 333 ? -87.714 -30.758 -45.181 1.00 87.98 ? 344 HIS B NE2 1 ATOM 7010 N N . ALA B 2 334 ? -86.683 -36.505 -44.560 1.00 81.75 ? 345 ALA B N 1 ATOM 7011 C CA . ALA B 2 334 ? -87.910 -37.287 -44.549 1.00 80.78 ? 345 ALA B CA 1 ATOM 7012 C C . ALA B 2 334 ? -88.551 -37.188 -43.175 1.00 67.19 ? 345 ALA B C 1 ATOM 7013 O O . ALA B 2 334 ? -87.910 -36.752 -42.221 1.00 65.85 ? 345 ALA B O 1 ATOM 7014 C CB . ALA B 2 334 ? -87.634 -38.727 -44.913 1.00 78.51 ? 345 ALA B CB 1 ATOM 7015 N N . SER B 2 335 ? -89.814 -37.582 -43.067 1.00 62.97 ? 346 SER B N 1 ATOM 7016 C CA . SER B 2 335 ? -90.533 -37.399 -41.813 1.00 70.99 ? 346 SER B CA 1 ATOM 7017 C C . SER B 2 335 ? -91.254 -38.663 -41.353 1.00 74.43 ? 346 SER B C 1 ATOM 7018 O O . SER B 2 335 ? -91.863 -39.381 -42.149 1.00 68.65 ? 346 SER B O 1 ATOM 7019 C CB . SER B 2 335 ? -91.521 -36.235 -41.941 1.00 74.33 ? 346 SER B CB 1 ATOM 7020 O OG . SER B 2 335 ? -90.847 -34.988 -41.865 1.00 62.13 ? 346 SER B OG 1 ATOM 7021 N N . VAL B 2 336 ? -91.162 -38.924 -40.051 1.00 76.86 ? 347 VAL B N 1 ATOM 7022 C CA . VAL B 2 336 ? -91.773 -40.086 -39.420 1.00 75.42 ? 347 VAL B CA 1 ATOM 7023 C C . VAL B 2 336 ? -92.706 -39.622 -38.303 1.00 79.96 ? 347 VAL B C 1 ATOM 7024 O O . VAL B 2 336 ? -92.744 -38.436 -37.967 1.00 71.66 ? 347 VAL B O 1 ATOM 7025 C CB . VAL B 2 336 ? -90.708 -41.052 -38.832 1.00 73.39 ? 347 VAL B CB 1 ATOM 7026 C CG1 . VAL B 2 336 ? -91.161 -42.502 -38.954 1.00 77.24 ? 347 VAL B CG1 1 ATOM 7027 C CG2 . VAL B 2 336 ? -89.371 -40.864 -39.527 1.00 70.26 ? 347 VAL B CG2 1 ATOM 7028 N N . LEU B 2 337 ? -93.450 -40.558 -37.723 1.00 88.87 ? 348 LEU B N 1 ATOM 7029 C CA . LEU B 2 337 ? -94.345 -40.234 -36.624 1.00 89.06 ? 348 LEU B CA 1 ATOM 7030 C C . LEU B 2 337 ? -94.199 -41.209 -35.457 1.00 97.49 ? 348 LEU B C 1 ATOM 7031 O O . LEU B 2 337 ? -94.159 -42.426 -35.642 1.00 99.37 ? 348 LEU B O 1 ATOM 7032 C CB . LEU B 2 337 ? -95.794 -40.205 -37.111 1.00 84.05 ? 348 LEU B CB 1 ATOM 7033 C CG . LEU B 2 337 ? -96.544 -38.953 -36.665 1.00 91.09 ? 348 LEU B CG 1 ATOM 7034 C CD1 . LEU B 2 337 ? -96.490 -38.872 -35.156 1.00 95.36 ? 348 LEU B CD1 1 ATOM 7035 C CD2 . LEU B 2 337 ? -95.936 -37.707 -37.293 1.00 94.38 ? 348 LEU B CD2 1 ATOM 7036 N N . LEU B 2 338 ? -94.119 -40.645 -34.256 1.00 97.61 ? 349 LEU B N 1 ATOM 7037 C CA . LEU B 2 338 ? -94.020 -41.397 -33.017 1.00 100.08 ? 349 LEU B CA 1 ATOM 7038 C C . LEU B 2 338 ? -95.333 -41.298 -32.245 1.00 108.78 ? 349 LEU B C 1 ATOM 7039 O O . LEU B 2 338 ? -95.680 -40.225 -31.747 1.00 111.01 ? 349 LEU B O 1 ATOM 7040 C CB . LEU B 2 338 ? -92.859 -40.865 -32.174 1.00 86.67 ? 349 LEU B CB 1 ATOM 7041 C CG . LEU B 2 338 ? -92.302 -41.786 -31.091 1.00 85.29 ? 349 LEU B CG 1 ATOM 7042 C CD1 . LEU B 2 338 ? -91.960 -43.137 -31.693 1.00 85.98 ? 349 LEU B CD1 1 ATOM 7043 C CD2 . LEU B 2 338 ? -91.078 -41.170 -30.439 1.00 85.64 ? 349 LEU B CD2 1 ATOM 7044 N N . HIS B 2 339 ? -96.070 -42.404 -32.151 1.00 108.34 ? 350 HIS B N 1 ATOM 7045 C CA . HIS B 2 339 ? -97.344 -42.388 -31.435 1.00 107.64 ? 350 HIS B CA 1 ATOM 7046 C C . HIS B 2 339 ? -97.794 -43.785 -30.959 1.00 112.33 ? 350 HIS B C 1 ATOM 7047 O O . HIS B 2 339 ? -97.037 -44.753 -31.044 1.00 109.64 ? 350 HIS B O 1 ATOM 7048 C CB . HIS B 2 339 ? -98.416 -41.701 -32.312 1.00 99.36 ? 350 HIS B CB 1 ATOM 7049 C CG . HIS B 2 339 ? -99.358 -42.636 -33.005 1.00 102.36 ? 350 HIS B CG 1 ATOM 7050 N ND1 . HIS B 2 339 ? -100.716 -42.412 -33.045 1.00 99.46 ? 350 HIS B ND1 1 ATOM 7051 C CD2 . HIS B 2 339 ? -99.146 -43.787 -33.685 1.00 104.38 ? 350 HIS B CD2 1 ATOM 7052 C CE1 . HIS B 2 339 ? -101.301 -43.390 -33.712 1.00 103.71 ? 350 HIS B CE1 1 ATOM 7053 N NE2 . HIS B 2 339 ? -100.372 -44.242 -34.103 1.00 110.79 ? 350 HIS B NE2 1 ATOM 7054 N N . LYS B 2 340 ? -99.032 -43.865 -30.470 1.00 120.66 ? 351 LYS B N 1 ATOM 7055 C CA . LYS B 2 340 ? -99.515 -44.993 -29.678 1.00 118.19 ? 351 LYS B CA 1 ATOM 7056 C C . LYS B 2 340 ? -100.816 -45.602 -30.207 1.00 118.38 ? 351 LYS B C 1 ATOM 7057 O O . LYS B 2 340 ? -101.651 -44.907 -30.789 1.00 117.13 ? 351 LYS B O 1 ATOM 7058 C CB . LYS B 2 340 ? -99.738 -44.558 -28.221 1.00 114.12 ? 351 LYS B CB 1 ATOM 7059 C CG . LYS B 2 340 ? -98.596 -43.782 -27.552 1.00 107.95 ? 351 LYS B CG 1 ATOM 7060 C CD . LYS B 2 340 ? -98.536 -42.294 -27.932 1.00 97.60 ? 351 LYS B CD 1 ATOM 7061 C CE . LYS B 2 340 ? -99.884 -41.702 -28.347 1.00 100.53 ? 351 LYS B CE 1 ATOM 7062 N NZ . LYS B 2 340 ? -100.902 -41.709 -27.268 1.00 115.75 ? 351 LYS B NZ 1 ATOM 7063 N N . ARG B 2 341 ? -100.988 -46.900 -29.970 1.00 115.31 ? 352 ARG B N 1 ATOM 7064 C CA . ARG B 2 341 ? -102.198 -47.623 -30.354 1.00 117.54 ? 352 ARG B CA 1 ATOM 7065 C C . ARG B 2 341 ? -103.251 -47.588 -29.245 1.00 123.70 ? 352 ARG B C 1 ATOM 7066 O O . ARG B 2 341 ? -102.974 -47.960 -28.104 1.00 134.02 ? 352 ARG B O 1 ATOM 7067 C CB . ARG B 2 341 ? -101.847 -49.068 -30.713 1.00 110.93 ? 352 ARG B CB 1 ATOM 7068 C CG . ARG B 2 341 ? -100.477 -49.494 -30.208 1.00 108.54 ? 352 ARG B CG 1 ATOM 7069 C CD . ARG B 2 341 ? -99.976 -50.738 -30.909 1.00 119.95 ? 352 ARG B CD 1 ATOM 7070 N NE . ARG B 2 341 ? -98.580 -51.021 -30.586 1.00 123.76 ? 352 ARG B NE 1 ATOM 7071 C CZ . ARG B 2 341 ? -97.867 -51.999 -31.133 1.00 132.35 ? 352 ARG B CZ 1 ATOM 7072 N NH1 . ARG B 2 341 ? -98.419 -52.795 -32.036 1.00 139.24 ? 352 ARG B NH1 1 ATOM 7073 N NH2 . ARG B 2 341 ? -96.602 -52.179 -30.776 1.00 116.45 ? 352 ARG B NH2 1 ATOM 7074 N N . LYS B 2 342 ? -104.460 -47.151 -29.591 1.00 118.10 ? 353 LYS B N 1 ATOM 7075 C CA . LYS B 2 342 ? -105.542 -47.001 -28.618 1.00 108.47 ? 353 LYS B CA 1 ATOM 7076 C C . LYS B 2 342 ? -106.137 -48.343 -28.198 1.00 114.02 ? 353 LYS B C 1 ATOM 7077 O O . LYS B 2 342 ? -105.475 -49.379 -28.277 1.00 119.54 ? 353 LYS B O 1 ATOM 7078 C CB . LYS B 2 342 ? -106.631 -46.106 -29.181 1.00 97.84 ? 353 LYS B CB 1 ATOM 7079 N N . HIS B 2 343 ? -107.391 -48.318 -27.750 1.00 117.09 ? 354 HIS B N 1 ATOM 7080 C CA . HIS B 2 343 ? -108.076 -49.529 -27.300 1.00 127.26 ? 354 HIS B CA 1 ATOM 7081 C C . HIS B 2 343 ? -108.273 -50.512 -28.451 1.00 136.35 ? 354 HIS B C 1 ATOM 7082 O O . HIS B 2 343 ? -108.371 -50.108 -29.608 1.00 146.59 ? 354 HIS B O 1 ATOM 7083 C CB . HIS B 2 343 ? -109.414 -49.179 -26.667 1.00 131.50 ? 354 HIS B CB 1 ATOM 7084 N N . HIS B 2 344 ? -108.343 -51.801 -28.128 1.00 132.11 ? 355 HIS B N 1 ATOM 7085 C CA . HIS B 2 344 ? -108.413 -52.846 -29.149 1.00 139.28 ? 355 HIS B CA 1 ATOM 7086 C C . HIS B 2 344 ? -109.730 -52.799 -29.928 1.00 155.20 ? 355 HIS B C 1 ATOM 7087 O O . HIS B 2 344 ? -110.630 -52.038 -29.571 1.00 159.83 ? 355 HIS B O 1 ATOM 7088 C CB . HIS B 2 344 ? -108.216 -54.223 -28.514 1.00 132.94 ? 355 HIS B CB 1 ATOM 7089 C CG . HIS B 2 344 ? -107.162 -55.046 -29.185 1.00 129.26 ? 355 HIS B CG 1 ATOM 7090 N ND1 . HIS B 2 344 ? -107.430 -56.264 -29.769 1.00 129.09 ? 355 HIS B ND1 1 ATOM 7091 C CD2 . HIS B 2 344 ? -105.842 -54.817 -29.379 1.00 123.35 ? 355 HIS B CD2 1 ATOM 7092 C CE1 . HIS B 2 344 ? -106.318 -56.755 -30.286 1.00 127.47 ? 355 HIS B CE1 1 ATOM 7093 N NE2 . HIS B 2 344 ? -105.340 -55.896 -30.063 1.00 130.23 ? 355 HIS B NE2 1 ATOM 7094 N N . HIS B 2 345 ? -109.838 -53.612 -30.983 1.00 158.67 ? 356 HIS B N 1 ATOM 7095 C CA . HIS B 2 345 ? -110.942 -53.509 -31.953 1.00 151.18 ? 356 HIS B CA 1 ATOM 7096 C C . HIS B 2 345 ? -112.326 -53.594 -31.307 1.00 147.61 ? 356 HIS B C 1 ATOM 7097 O O . HIS B 2 345 ? -113.058 -54.573 -31.460 1.00 135.24 ? 356 HIS B O 1 ATOM 7098 C CB . HIS B 2 345 ? -110.804 -54.573 -33.057 1.00 143.35 ? 356 HIS B CB 1 ATOM 7099 C CG . HIS B 2 345 ? -110.591 -55.970 -32.560 1.00 146.38 ? 356 HIS B CG 1 ATOM 7100 N ND1 . HIS B 2 345 ? -109.348 -56.563 -32.524 1.00 146.01 ? 356 HIS B ND1 1 ATOM 7101 C CD2 . HIS B 2 345 ? -111.466 -56.907 -32.121 1.00 141.13 ? 356 HIS B CD2 1 ATOM 7102 C CE1 . HIS B 2 345 ? -109.462 -57.796 -32.064 1.00 144.42 ? 356 HIS B CE1 1 ATOM 7103 N NE2 . HIS B 2 345 ? -110.737 -58.029 -31.810 1.00 143.22 ? 356 HIS B NE2 1 ATOM 7104 N N . HIS B 2 346 ? -112.668 -52.529 -30.591 1.00 155.13 ? 357 HIS B N 1 ATOM 7105 C CA . HIS B 2 346 ? -113.869 -52.468 -29.774 1.00 153.82 ? 357 HIS B CA 1 ATOM 7106 C C . HIS B 2 346 ? -114.590 -51.144 -30.027 1.00 159.45 ? 357 HIS B C 1 ATOM 7107 O O . HIS B 2 346 ? -114.393 -50.172 -29.295 1.00 163.78 ? 357 HIS B O 1 ATOM 7108 C CB . HIS B 2 346 ? -113.510 -52.603 -28.290 1.00 152.21 ? 357 HIS B CB 1 ATOM 7109 C CG . HIS B 2 346 ? -113.015 -53.962 -27.891 1.00 149.83 ? 357 HIS B CG 1 ATOM 7110 N ND1 . HIS B 2 346 ? -113.399 -54.574 -26.718 1.00 153.65 ? 357 HIS B ND1 1 ATOM 7111 C CD2 . HIS B 2 346 ? -112.150 -54.813 -28.491 1.00 145.77 ? 357 HIS B CD2 1 ATOM 7112 C CE1 . HIS B 2 346 ? -112.803 -55.749 -26.619 1.00 156.27 ? 357 HIS B CE1 1 ATOM 7113 N NE2 . HIS B 2 346 ? -112.039 -55.918 -27.683 1.00 145.69 ? 357 HIS B NE2 1 ATOM 7114 N N . HIS B 2 347 ? -115.425 -51.107 -31.059 1.00 156.40 ? 358 HIS B N 1 ATOM 7115 C CA . HIS B 2 347 ? -116.017 -49.852 -31.519 1.00 156.63 ? 358 HIS B CA 1 ATOM 7116 C C . HIS B 2 347 ? -117.424 -50.050 -32.086 1.00 146.17 ? 358 HIS B C 1 ATOM 7117 O O . HIS B 2 347 ? -118.286 -49.182 -31.948 1.00 148.84 ? 358 HIS B O 1 ATOM 7118 C CB . HIS B 2 347 ? -115.103 -49.205 -32.571 1.00 149.18 ? 358 HIS B CB 1 ATOM 7119 C CG . HIS B 2 347 ? -115.617 -47.910 -33.125 1.00 141.49 ? 358 HIS B CG 1 ATOM 7120 N ND1 . HIS B 2 347 ? -116.157 -47.806 -34.388 1.00 133.73 ? 358 HIS B ND1 1 ATOM 7121 C CD2 . HIS B 2 347 ? -115.646 -46.661 -32.602 1.00 138.42 ? 358 HIS B CD2 1 ATOM 7122 C CE1 . HIS B 2 347 ? -116.510 -46.553 -34.614 1.00 136.81 ? 358 HIS B CE1 1 ATOM 7123 N NE2 . HIS B 2 347 ? -116.210 -45.837 -33.546 1.00 138.29 ? 358 HIS B NE2 1 HETATM 7124 C C1 . NAG C 3 . ? -20.482 -20.311 -36.158 1.00 158.61 ? 401 NAG B C1 1 HETATM 7125 C C2 . NAG C 3 . ? -21.964 -20.239 -36.596 1.00 159.70 ? 401 NAG B C2 1 HETATM 7126 C C3 . NAG C 3 . ? -22.454 -18.789 -36.660 1.00 155.19 ? 401 NAG B C3 1 HETATM 7127 C C4 . NAG C 3 . ? -22.148 -18.054 -35.364 1.00 147.20 ? 401 NAG B C4 1 HETATM 7128 C C5 . NAG C 3 . ? -20.656 -18.144 -35.083 1.00 151.30 ? 401 NAG B C5 1 HETATM 7129 C C6 . NAG C 3 . ? -20.247 -17.434 -33.813 1.00 157.26 ? 401 NAG B C6 1 HETATM 7130 C C7 . NAG C 3 . ? -21.739 -20.472 -39.053 1.00 148.68 ? 401 NAG B C7 1 HETATM 7131 C C8 . NAG C 3 . ? -22.107 -21.308 -40.241 1.00 134.63 ? 401 NAG B C8 1 HETATM 7132 N N2 . NAG C 3 . ? -22.189 -20.912 -37.869 1.00 157.31 ? 401 NAG B N2 1 HETATM 7133 O O3 . NAG C 3 . ? -23.855 -18.775 -36.910 1.00 154.32 ? 401 NAG B O3 1 HETATM 7134 O O4 . NAG C 3 . ? -22.537 -16.690 -35.475 1.00 132.21 ? 401 NAG B O4 1 HETATM 7135 O O5 . NAG C 3 . ? -20.286 -19.525 -34.943 1.00 152.81 ? 401 NAG B O5 1 HETATM 7136 O O6 . NAG C 3 . ? -20.102 -16.037 -34.031 1.00 151.85 ? 401 NAG B O6 1 HETATM 7137 O O7 . NAG C 3 . ? -21.060 -19.454 -39.164 1.00 144.54 ? 401 NAG B O7 1 HETATM 7138 C C1 . NAG D 3 . ? -38.057 -61.119 -53.218 1.00 137.96 ? 402 NAG B C1 1 HETATM 7139 C C2 . NAG D 3 . ? -39.161 -62.137 -53.559 1.00 143.55 ? 402 NAG B C2 1 HETATM 7140 C C3 . NAG D 3 . ? -38.827 -62.897 -54.852 1.00 145.83 ? 402 NAG B C3 1 HETATM 7141 C C4 . NAG D 3 . ? -38.445 -61.936 -55.971 1.00 141.37 ? 402 NAG B C4 1 HETATM 7142 C C5 . NAG D 3 . ? -37.332 -61.014 -55.492 1.00 143.18 ? 402 NAG B C5 1 HETATM 7143 C C6 . NAG D 3 . ? -36.905 -59.993 -56.521 1.00 127.36 ? 402 NAG B C6 1 HETATM 7144 C C7 . NAG D 3 . ? -40.461 -63.798 -52.295 1.00 123.08 ? 402 NAG B C7 1 HETATM 7145 C C8 . NAG D 3 . ? -40.486 -64.705 -51.102 1.00 111.40 ? 402 NAG B C8 1 HETATM 7146 N N2 . NAG D 3 . ? -39.354 -63.067 -52.455 1.00 135.43 ? 402 NAG B N2 1 HETATM 7147 O O3 . NAG D 3 . ? -39.945 -63.682 -55.253 1.00 134.14 ? 402 NAG B O3 1 HETATM 7148 O O4 . NAG D 3 . ? -38.009 -62.654 -57.120 1.00 137.60 ? 402 NAG B O4 1 HETATM 7149 O O5 . NAG D 3 . ? -37.799 -60.286 -54.351 1.00 148.38 ? 402 NAG B O5 1 HETATM 7150 O O6 . NAG D 3 . ? -35.632 -59.447 -56.202 1.00 109.34 ? 402 NAG B O6 1 HETATM 7151 O O7 . NAG D 3 . ? -41.398 -63.734 -53.080 1.00 122.58 ? 402 NAG B O7 1 HETATM 7152 C C1 . NAG E 3 . ? -52.726 -55.788 -55.003 1.00 111.81 ? 403 NAG B C1 1 HETATM 7153 C C2 . NAG E 3 . ? -53.543 -57.069 -55.163 1.00 113.58 ? 403 NAG B C2 1 HETATM 7154 C C3 . NAG E 3 . ? -54.323 -57.358 -53.882 1.00 126.34 ? 403 NAG B C3 1 HETATM 7155 C C4 . NAG E 3 . ? -53.387 -57.361 -52.677 1.00 132.23 ? 403 NAG B C4 1 HETATM 7156 C C5 . NAG E 3 . ? -52.558 -56.079 -52.644 1.00 126.05 ? 403 NAG B C5 1 HETATM 7157 C C6 . NAG E 3 . ? -51.503 -56.077 -51.562 1.00 125.15 ? 403 NAG B C6 1 HETATM 7158 C C7 . NAG E 3 . ? -54.713 -58.035 -57.093 1.00 112.56 ? 403 NAG B C7 1 HETATM 7159 C C8 . NAG E 3 . ? -55.655 -57.775 -58.229 1.00 115.05 ? 403 NAG B C8 1 HETATM 7160 N N2 . NAG E 3 . ? -54.439 -56.988 -56.306 1.00 107.70 ? 403 NAG B N2 1 HETATM 7161 O O3 . NAG E 3 . ? -54.984 -58.612 -54.009 1.00 136.82 ? 403 NAG B O3 1 HETATM 7162 O O4 . NAG E 3 . ? -54.122 -57.470 -51.463 1.00 138.02 ? 403 NAG B O4 1 HETATM 7163 O O5 . NAG E 3 . ? -51.864 -55.914 -53.888 1.00 121.85 ? 403 NAG B O5 1 HETATM 7164 O O6 . NAG E 3 . ? -50.712 -57.258 -51.584 1.00 121.18 ? 403 NAG B O6 1 HETATM 7165 O O7 . NAG E 3 . ? -54.223 -59.142 -56.895 1.00 110.57 ? 403 NAG B O7 1 HETATM 7166 C C1 . NAG F 3 . ? -54.156 -58.848 -51.041 1.00 139.16 ? 404 NAG B C1 1 HETATM 7167 C C2 . NAG F 3 . ? -53.974 -58.952 -49.525 1.00 127.72 ? 404 NAG B C2 1 HETATM 7168 C C3 . NAG F 3 . ? -54.026 -60.413 -49.087 1.00 136.70 ? 404 NAG B C3 1 HETATM 7169 C C4 . NAG F 3 . ? -55.302 -61.072 -49.593 1.00 141.37 ? 404 NAG B C4 1 HETATM 7170 C C5 . NAG F 3 . ? -55.417 -60.894 -51.103 1.00 150.39 ? 404 NAG B C5 1 HETATM 7171 C C6 . NAG F 3 . ? -56.710 -61.435 -51.665 1.00 151.02 ? 404 NAG B C6 1 HETATM 7172 C C7 . NAG F 3 . ? -52.667 -57.121 -48.540 1.00 124.69 ? 404 NAG B C7 1 HETATM 7173 C C8 . NAG F 3 . ? -51.302 -56.651 -48.138 1.00 119.56 ? 404 NAG B C8 1 HETATM 7174 N N2 . NAG F 3 . ? -52.730 -58.337 -49.093 1.00 119.94 ? 404 NAG B N2 1 HETATM 7175 O O3 . NAG F 3 . ? -53.971 -60.485 -47.667 1.00 152.24 ? 404 NAG B O3 1 HETATM 7176 O O4 . NAG F 3 . ? -55.294 -62.460 -49.278 1.00 138.29 ? 404 NAG B O4 1 HETATM 7177 O O5 . NAG F 3 . ? -55.376 -59.496 -51.427 1.00 155.46 ? 404 NAG B O5 1 HETATM 7178 O O6 . NAG F 3 . ? -56.503 -62.639 -52.390 1.00 142.98 ? 404 NAG B O6 1 HETATM 7179 O O7 . NAG F 3 . ? -53.667 -56.429 -48.378 1.00 128.09 ? 404 NAG B O7 1 HETATM 7180 C C1 . NAG G 3 . ? -82.487 -50.184 -34.188 1.00 110.61 ? 405 NAG B C1 1 HETATM 7181 C C2 . NAG G 3 . ? -81.156 -50.715 -33.693 1.00 115.49 ? 405 NAG B C2 1 HETATM 7182 C C3 . NAG G 3 . ? -80.308 -51.169 -34.875 1.00 118.38 ? 405 NAG B C3 1 HETATM 7183 C C4 . NAG G 3 . ? -81.072 -52.161 -35.746 1.00 119.45 ? 405 NAG B C4 1 HETATM 7184 C C5 . NAG G 3 . ? -82.485 -51.665 -36.078 1.00 109.37 ? 405 NAG B C5 1 HETATM 7185 C C6 . NAG G 3 . ? -83.354 -52.748 -36.678 1.00 86.14 ? 405 NAG B C6 1 HETATM 7186 C C7 . NAG G 3 . ? -80.182 -49.860 -31.606 1.00 115.03 ? 405 NAG B C7 1 HETATM 7187 C C8 . NAG G 3 . ? -80.642 -51.142 -30.978 1.00 113.10 ? 405 NAG B C8 1 HETATM 7188 N N2 . NAG G 3 . ? -80.452 -49.714 -32.908 1.00 112.06 ? 405 NAG B N2 1 HETATM 7189 O O3 . NAG G 3 . ? -79.110 -51.766 -34.391 1.00 125.89 ? 405 NAG B O3 1 HETATM 7190 O O4 . NAG G 3 . ? -80.372 -52.341 -36.973 1.00 126.06 ? 405 NAG B O4 1 HETATM 7191 O O5 . NAG G 3 . ? -83.169 -51.205 -34.900 1.00 115.81 ? 405 NAG B O5 1 HETATM 7192 O O6 . NAG G 3 . ? -83.716 -52.460 -38.022 1.00 70.91 ? 405 NAG B O6 1 HETATM 7193 O O7 . NAG G 3 . ? -79.590 -48.999 -30.965 1.00 113.69 ? 405 NAG B O7 1 HETATM 7194 C C1 . NAG H 3 . ? -79.557 -53.537 -37.012 1.00 139.25 ? 406 NAG B C1 1 HETATM 7195 C C2 . NAG H 3 . ? -78.708 -53.492 -38.264 1.00 143.76 ? 406 NAG B C2 1 HETATM 7196 C C3 . NAG H 3 . ? -78.007 -54.831 -38.472 1.00 158.30 ? 406 NAG B C3 1 HETATM 7197 C C4 . NAG H 3 . ? -77.312 -55.313 -37.197 1.00 167.39 ? 406 NAG B C4 1 HETATM 7198 C C5 . NAG H 3 . ? -78.164 -55.102 -35.939 1.00 164.61 ? 406 NAG B C5 1 HETATM 7199 C C6 . NAG H 3 . ? -77.367 -55.251 -34.663 1.00 165.23 ? 406 NAG B C6 1 HETATM 7200 C C7 . NAG H 3 . ? -79.506 -51.952 -40.002 1.00 123.95 ? 406 NAG B C7 1 HETATM 7201 C C8 . NAG H 3 . ? -80.419 -51.780 -41.176 1.00 118.61 ? 406 NAG B C8 1 HETATM 7202 N N2 . NAG H 3 . ? -79.521 -53.155 -39.421 1.00 133.82 ? 406 NAG B N2 1 HETATM 7203 O O3 . NAG H 3 . ? -77.061 -54.665 -39.523 1.00 158.01 ? 406 NAG B O3 1 HETATM 7204 O O4 . NAG H 3 . ? -77.040 -56.710 -37.297 1.00 176.62 ? 406 NAG B O4 1 HETATM 7205 O O5 . NAG H 3 . ? -78.739 -53.787 -35.906 1.00 148.09 ? 406 NAG B O5 1 HETATM 7206 O O6 . NAG H 3 . ? -77.145 -56.616 -34.339 1.00 173.05 ? 406 NAG B O6 1 HETATM 7207 O O7 . NAG H 3 . ? -78.785 -51.044 -39.600 1.00 122.06 ? 406 NAG B O7 1 HETATM 7208 C C1 . BMA I 4 . ? -75.820 -56.963 -38.025 1.00 176.47 ? 407 BMA B C1 1 HETATM 7209 C C2 . BMA I 4 . ? -74.832 -57.906 -37.329 1.00 178.95 ? 407 BMA B C2 1 HETATM 7210 C C3 . BMA I 4 . ? -73.468 -57.554 -37.944 1.00 180.73 ? 407 BMA B C3 1 HETATM 7211 C C4 . BMA I 4 . ? -73.485 -57.594 -39.521 1.00 176.20 ? 407 BMA B C4 1 HETATM 7212 C C5 . BMA I 4 . ? -74.784 -56.959 -40.151 1.00 176.17 ? 407 BMA B C5 1 HETATM 7213 C C6 . BMA I 4 . ? -75.034 -57.258 -41.662 1.00 174.85 ? 407 BMA B C6 1 HETATM 7214 O O2 . BMA I 4 . ? -75.124 -59.256 -37.646 1.00 182.17 ? 407 BMA B O2 1 HETATM 7215 O O3 . BMA I 4 . ? -72.265 -58.191 -37.316 1.00 197.74 ? 407 BMA B O3 1 HETATM 7216 O O4 . BMA I 4 . ? -72.350 -56.912 -40.019 1.00 174.42 ? 407 BMA B O4 1 HETATM 7217 O O5 . BMA I 4 . ? -75.958 -57.332 -39.383 1.00 179.19 ? 407 BMA B O5 1 HETATM 7218 O O6 . BMA I 4 . ? -74.598 -58.589 -42.052 1.00 176.17 ? 407 BMA B O6 1 HETATM 7219 C C1 . MAN J 5 . ? -71.935 -59.616 -37.381 1.00 196.06 ? 408 MAN B C1 1 HETATM 7220 C C2 . MAN J 5 . ? -71.575 -60.221 -38.790 1.00 201.10 ? 408 MAN B C2 1 HETATM 7221 C C3 . MAN J 5 . ? -70.805 -61.533 -38.612 1.00 199.59 ? 408 MAN B C3 1 HETATM 7222 C C4 . MAN J 5 . ? -70.666 -61.892 -37.118 1.00 186.78 ? 408 MAN B C4 1 HETATM 7223 C C5 . MAN J 5 . ? -72.078 -61.878 -36.459 1.00 177.94 ? 408 MAN B C5 1 HETATM 7224 C C6 . MAN J 5 . ? -72.049 -62.251 -34.990 1.00 157.61 ? 408 MAN B C6 1 HETATM 7225 O O2 . MAN J 5 . ? -70.693 -59.367 -39.514 1.00 205.75 ? 408 MAN B O2 1 HETATM 7226 O O3 . MAN J 5 . ? -69.526 -61.485 -39.240 1.00 203.08 ? 408 MAN B O3 1 HETATM 7227 O O4 . MAN J 5 . ? -70.050 -63.165 -36.967 1.00 177.18 ? 408 MAN B O4 1 HETATM 7228 O O5 . MAN J 5 . ? -72.679 -60.530 -36.566 1.00 185.23 ? 408 MAN B O5 1 HETATM 7229 O O6 . MAN J 5 . ? -73.190 -63.055 -34.705 1.00 146.60 ? 408 MAN B O6 1 HETATM 7230 C C1 . MAN K 5 . ? -73.313 -58.622 -42.735 1.00 183.16 ? 409 MAN B C1 1 HETATM 7231 C C2 . MAN K 5 . ? -72.819 -57.213 -43.250 1.00 186.47 ? 409 MAN B C2 1 HETATM 7232 C C3 . MAN K 5 . ? -73.261 -56.937 -44.700 1.00 185.61 ? 409 MAN B C3 1 HETATM 7233 C C4 . MAN K 5 . ? -72.965 -58.141 -45.586 1.00 188.21 ? 409 MAN B C4 1 HETATM 7234 C C5 . MAN K 5 . ? -73.722 -59.353 -45.037 1.00 192.96 ? 409 MAN B C5 1 HETATM 7235 C C6 . MAN K 5 . ? -73.540 -60.592 -45.893 1.00 192.90 ? 409 MAN B C6 1 HETATM 7236 O O2 . MAN K 5 . ? -71.386 -57.112 -43.239 1.00 185.51 ? 409 MAN B O2 1 HETATM 7237 O O3 . MAN K 5 . ? -72.646 -55.765 -45.236 1.00 174.54 ? 409 MAN B O3 1 HETATM 7238 O O4 . MAN K 5 . ? -73.380 -57.878 -46.921 1.00 169.71 ? 409 MAN B O4 1 HETATM 7239 O O5 . MAN K 5 . ? -73.222 -59.659 -43.710 1.00 186.39 ? 409 MAN B O5 1 HETATM 7240 O O6 . MAN K 5 . ? -74.801 -61.238 -46.018 1.00 196.82 ? 409 MAN B O6 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLU 1 28 28 GLU GLU A . n A 1 2 THR 2 29 29 THR THR A . n A 1 3 PRO 3 30 30 PRO PRO A . n A 1 4 PRO 4 31 31 PRO PRO A . n A 1 5 ARG 5 32 32 ARG ARG A . n A 1 6 PHE 6 33 33 PHE PHE A . n A 1 7 THR 7 34 34 THR THR A . n A 1 8 ARG 8 35 35 ARG ARG A . n A 1 9 THR 9 36 36 THR THR A . n A 1 10 PRO 10 37 37 PRO PRO A . n A 1 11 VAL 11 38 38 VAL VAL A . n A 1 12 ASP 12 39 39 ASP ASP A . n A 1 13 GLN 13 40 40 GLN GLN A . n A 1 14 THR 14 41 41 THR THR A . n A 1 15 GLY 15 42 42 GLY GLY A . n A 1 16 VAL 16 43 43 VAL VAL A . n A 1 17 SER 17 44 44 SER SER A . n A 1 18 GLY 18 45 45 GLY GLY A . n A 1 19 GLY 19 46 46 GLY GLY A . n A 1 20 VAL 20 47 47 VAL VAL A . n A 1 21 ALA 21 48 48 ALA ALA A . n A 1 22 SER 22 49 49 SER SER A . n A 1 23 PHE 23 50 50 PHE PHE A . n A 1 24 ILE 24 51 51 ILE ILE A . n A 1 25 CYS 25 52 52 CYS CYS A . n A 1 26 GLN 26 53 53 GLN GLN A . n A 1 27 ALA 27 54 54 ALA ALA A . n A 1 28 THR 28 55 55 THR THR A . n A 1 29 GLY 29 56 56 GLY GLY A . n A 1 30 ASP 30 57 57 ASP ASP A . n A 1 31 PRO 31 58 58 PRO PRO A . n A 1 32 ARG 32 59 59 ARG ARG A . n A 1 33 PRO 33 60 60 PRO PRO A . n A 1 34 LYS 34 61 61 LYS LYS A . n A 1 35 ILE 35 62 62 ILE ILE A . n A 1 36 VAL 36 63 63 VAL VAL A . n A 1 37 TRP 37 64 64 TRP TRP A . n A 1 38 ASN 38 65 65 ASN ASN A . n A 1 39 LYS 39 66 66 LYS LYS A . n A 1 40 LYS 40 67 67 LYS LYS A . n A 1 41 GLY 41 68 68 GLY GLY A . n A 1 42 LYS 42 69 69 LYS LYS A . n A 1 43 LYS 43 70 70 LYS LYS A . n A 1 44 VAL 44 71 71 VAL VAL A . n A 1 45 SER 45 72 72 SER SER A . n A 1 46 ASN 46 73 73 ASN ASN A . n A 1 47 GLN 47 74 74 GLN GLN A . n A 1 48 ARG 48 75 75 ARG ARG A . n A 1 49 PHE 49 76 76 PHE PHE A . n A 1 50 GLU 50 77 77 GLU GLU A . n A 1 51 VAL 51 78 78 VAL VAL A . n A 1 52 ILE 52 79 79 ILE ILE A . n A 1 53 GLU 53 80 80 GLU GLU A . n A 1 54 PHE 54 81 81 PHE PHE A . n A 1 55 ASP 55 82 82 ASP ASP A . n A 1 56 ASP 56 83 83 ASP ASP A . n A 1 57 GLY 57 84 84 GLY GLY A . n A 1 58 SER 58 85 85 SER SER A . n A 1 59 GLY 59 86 86 GLY GLY A . n A 1 60 SER 60 87 87 SER SER A . n A 1 61 VAL 61 88 88 VAL VAL A . n A 1 62 LEU 62 89 89 LEU LEU A . n A 1 63 ARG 63 90 90 ARG ARG A . n A 1 64 ILE 64 91 91 ILE ILE A . n A 1 65 GLN 65 92 92 GLN GLN A . n A 1 66 PRO 66 93 93 PRO PRO A . n A 1 67 LEU 67 94 94 LEU LEU A . n A 1 68 ARG 68 95 95 ARG ARG A . n A 1 69 THR 69 96 96 THR THR A . n A 1 70 PRO 70 97 97 PRO PRO A . n A 1 71 ARG 71 98 98 ARG ARG A . n A 1 72 ASP 72 99 99 ASP ASP A . n A 1 73 GLU 73 100 100 GLU GLU A . n A 1 74 ALA 74 101 101 ALA ALA A . n A 1 75 ILE 75 102 102 ILE ILE A . n A 1 76 TYR 76 103 103 TYR TYR A . n A 1 77 GLU 77 104 104 GLU GLU A . n A 1 78 CYS 78 105 105 CYS CYS A . n A 1 79 VAL 79 106 106 VAL VAL A . n A 1 80 ALA 80 107 107 ALA ALA A . n A 1 81 SER 81 108 108 SER SER A . n A 1 82 ASN 82 109 109 ASN ASN A . n A 1 83 ASN 83 110 110 ASN ASN A . n A 1 84 VAL 84 111 111 VAL VAL A . n A 1 85 GLY 85 112 112 GLY GLY A . n A 1 86 GLU 86 113 113 GLU GLU A . n A 1 87 ILE 87 114 114 ILE ILE A . n A 1 88 SER 88 115 115 SER SER A . n A 1 89 VAL 89 116 116 VAL VAL A . n A 1 90 SER 90 117 117 SER SER A . n A 1 91 THR 91 118 118 THR THR A . n A 1 92 ARG 92 119 119 ARG ARG A . n A 1 93 LEU 93 120 120 LEU LEU A . n A 1 94 THR 94 121 121 THR THR A . n A 1 95 VAL 95 122 122 VAL VAL A . n A 1 96 LEU 96 123 123 LEU LEU A . n A 1 97 ARG 97 124 124 ARG ARG A . n A 1 98 GLU 98 125 125 GLU GLU A . n A 1 99 ASP 99 126 126 ASP ASP A . n A 1 100 GLN 100 127 127 GLN GLN A . n A 1 101 ILE 101 128 128 ILE ILE A . n A 1 102 PRO 102 129 129 PRO PRO A . n A 1 103 ARG 103 130 130 ARG ARG A . n A 1 104 GLY 104 131 131 GLY GLY A . n A 1 105 PHE 105 132 132 PHE PHE A . n A 1 106 PRO 106 133 133 PRO PRO A . n A 1 107 THR 107 134 134 THR THR A . n A 1 108 ILE 108 135 135 ILE ILE A . n A 1 109 ASP 109 136 136 ASP ASP A . n A 1 110 MET 110 137 137 MET MET A . n A 1 111 GLY 111 138 138 GLY GLY A . n A 1 112 PRO 112 139 139 PRO PRO A . n A 1 113 GLN 113 140 140 GLN GLN A . n A 1 114 LEU 114 141 141 LEU LEU A . n A 1 115 LYS 115 142 142 LYS LYS A . n A 1 116 VAL 116 143 143 VAL VAL A . n A 1 117 VAL 117 144 144 VAL VAL A . n A 1 118 GLU 118 145 145 GLU GLU A . n A 1 119 ARG 119 146 146 ARG ARG A . n A 1 120 THR 120 147 147 THR THR A . n A 1 121 ARG 121 148 148 ARG ARG A . n A 1 122 THR 122 149 149 THR THR A . n A 1 123 ALA 123 150 150 ALA ALA A . n A 1 124 THR 124 151 151 THR THR A . n A 1 125 MET 125 152 152 MET MET A . n A 1 126 LEU 126 153 153 LEU LEU A . n A 1 127 CYS 127 154 154 CYS CYS A . n A 1 128 ALA 128 155 155 ALA ALA A . n A 1 129 ALA 129 156 156 ALA ALA A . n A 1 130 SER 130 157 157 SER SER A . n A 1 131 GLY 131 158 158 GLY GLY A . n A 1 132 ASN 132 159 159 ASN ASN A . n A 1 133 PRO 133 160 160 PRO PRO A . n A 1 134 ASP 134 161 161 ASP ASP A . n A 1 135 PRO 135 162 162 PRO PRO A . n A 1 136 GLU 136 163 163 GLU GLU A . n A 1 137 ILE 137 164 164 ILE ILE A . n A 1 138 THR 138 165 165 THR THR A . n A 1 139 TRP 139 166 166 TRP TRP A . n A 1 140 PHE 140 167 167 PHE PHE A . n A 1 141 LYS 141 168 168 LYS LYS A . n A 1 142 ASP 142 169 169 ASP ASP A . n A 1 143 PHE 143 170 170 PHE PHE A . n A 1 144 LEU 144 171 171 LEU LEU A . n A 1 145 PRO 145 172 172 PRO PRO A . n A 1 146 VAL 146 173 173 VAL VAL A . n A 1 147 ASP 147 174 174 ASP ASP A . n A 1 148 THR 148 175 175 THR THR A . n A 1 149 SER 149 176 176 SER SER A . n A 1 150 ASN 150 177 177 ASN ASN A . n A 1 151 ASN 151 178 178 ASN ASN A . n A 1 152 ASN 152 179 179 ASN ASN A . n A 1 153 GLY 153 180 180 GLY GLY A . n A 1 154 ARG 154 181 181 ARG ARG A . n A 1 155 ILE 155 182 182 ILE ILE A . n A 1 156 LYS 156 183 183 LYS LYS A . n A 1 157 GLN 157 184 184 GLN GLN A . n A 1 158 LEU 158 185 185 LEU LEU A . n A 1 159 ARG 159 186 186 ARG ARG A . n A 1 160 SER 160 187 187 SER SER A . n A 1 161 GLU 161 188 188 GLU GLU A . n A 1 162 SER 162 189 189 SER SER A . n A 1 163 ILE 163 190 190 ILE ILE A . n A 1 164 GLY 164 191 191 GLY GLY A . n A 1 165 GLY 165 192 192 GLY GLY A . n A 1 166 THR 166 193 193 THR THR A . n A 1 167 PRO 167 194 194 PRO PRO A . n A 1 168 ILE 168 195 195 ILE ILE A . n A 1 169 ARG 169 196 196 ARG ARG A . n A 1 170 GLY 170 197 197 GLY GLY A . n A 1 171 ALA 171 198 198 ALA ALA A . n A 1 172 LEU 172 199 199 LEU LEU A . n A 1 173 GLN 173 200 200 GLN GLN A . n A 1 174 ILE 174 201 201 ILE ILE A . n A 1 175 GLU 175 202 202 GLU GLU A . n A 1 176 GLN 176 203 203 GLN GLN A . n A 1 177 SER 177 204 204 SER SER A . n A 1 178 GLU 178 205 205 GLU GLU A . n A 1 179 GLU 179 206 206 GLU GLU A . n A 1 180 SER 180 207 207 SER SER A . n A 1 181 ASP 181 208 208 ASP ASP A . n A 1 182 GLN 182 209 209 GLN GLN A . n A 1 183 GLY 183 210 210 GLY GLY A . n A 1 184 LYS 184 211 211 LYS LYS A . n A 1 185 TYR 185 212 212 TYR TYR A . n A 1 186 GLU 186 213 213 GLU GLU A . n A 1 187 CYS 187 214 214 CYS CYS A . n A 1 188 VAL 188 215 215 VAL VAL A . n A 1 189 ALA 189 216 216 ALA ALA A . n A 1 190 THR 190 217 217 THR THR A . n A 1 191 ASN 191 218 218 ASN ASN A . n A 1 192 SER 192 219 219 SER SER A . n A 1 193 ALA 193 220 220 ALA ALA A . n A 1 194 GLY 194 221 221 GLY GLY A . n A 1 195 THR 195 222 222 THR THR A . n A 1 196 ARG 196 223 223 ARG ARG A . n A 1 197 TYR 197 224 224 TYR TYR A . n A 1 198 SER 198 225 225 SER SER A . n A 1 199 ALA 199 226 226 ALA ALA A . n A 1 200 PRO 200 227 227 PRO PRO A . n A 1 201 ALA 201 228 228 ALA ALA A . n A 1 202 ASN 202 229 229 ASN ASN A . n A 1 203 LEU 203 230 230 LEU LEU A . n A 1 204 TYR 204 231 231 TYR TYR A . n A 1 205 VAL 205 232 232 VAL VAL A . n A 1 206 ARG 206 233 233 ARG ARG A . n A 1 207 GLU 207 234 234 GLU GLU A . n A 1 208 LEU 208 235 235 LEU LEU A . n A 1 209 ARG 209 236 236 ARG ARG A . n A 1 210 GLU 210 237 237 GLU GLU A . n A 1 211 VAL 211 238 238 VAL VAL A . n A 1 212 ARG 212 239 239 ARG ARG A . n A 1 213 ARG 213 240 240 ARG ARG A . n A 1 214 VAL 214 241 241 VAL VAL A . n A 1 215 PRO 215 242 242 PRO PRO A . n A 1 216 PRO 216 243 243 PRO PRO A . n A 1 217 ARG 217 244 244 ARG ARG A . n A 1 218 PHE 218 245 245 PHE PHE A . n A 1 219 SER 219 246 246 SER SER A . n A 1 220 ILE 220 247 247 ILE ILE A . n A 1 221 PRO 221 248 248 PRO PRO A . n A 1 222 PRO 222 249 249 PRO PRO A . n A 1 223 THR 223 250 250 THR THR A . n A 1 224 ASN 224 251 251 ASN ASN A . n A 1 225 HIS 225 252 252 HIS HIS A . n A 1 226 GLU 226 253 253 GLU GLU A . n A 1 227 ILE 227 254 254 ILE ILE A . n A 1 228 MET 228 255 255 MET MET A . n A 1 229 PRO 229 256 256 PRO PRO A . n A 1 230 GLY 230 257 257 GLY GLY A . n A 1 231 GLY 231 258 258 GLY GLY A . n A 1 232 SER 232 259 259 SER SER A . n A 1 233 VAL 233 260 260 VAL VAL A . n A 1 234 ASN 234 261 261 ASN ASN A . n A 1 235 ILE 235 262 262 ILE ILE A . n A 1 236 THR 236 263 263 THR THR A . n A 1 237 CYS 237 264 264 CYS CYS A . n A 1 238 VAL 238 265 265 VAL VAL A . n A 1 239 ALA 239 266 266 ALA ALA A . n A 1 240 VAL 240 267 267 VAL VAL A . n A 1 241 GLY 241 268 268 GLY GLY A . n A 1 242 SER 242 269 269 SER SER A . n A 1 243 PRO 243 270 270 PRO PRO A . n A 1 244 MET 244 271 271 MET MET A . n A 1 245 PRO 245 272 272 PRO PRO A . n A 1 246 TYR 246 273 273 TYR TYR A . n A 1 247 VAL 247 274 274 VAL VAL A . n A 1 248 LYS 248 275 275 LYS LYS A . n A 1 249 TRP 249 276 276 TRP TRP A . n A 1 250 MET 250 277 277 MET MET A . n A 1 251 LEU 251 278 278 LEU LEU A . n A 1 252 GLY 252 279 279 GLY GLY A . n A 1 253 ALA 253 280 280 ALA ALA A . n A 1 254 GLU 254 281 281 GLU GLU A . n A 1 255 ASP 255 282 282 ASP ASP A . n A 1 256 LEU 256 283 283 LEU LEU A . n A 1 257 THR 257 284 284 THR THR A . n A 1 258 PRO 258 285 285 PRO PRO A . n A 1 259 GLU 259 286 286 GLU GLU A . n A 1 260 ASP 260 287 287 ASP ASP A . n A 1 261 ASP 261 288 288 ASP ASP A . n A 1 262 MET 262 289 289 MET MET A . n A 1 263 PRO 263 290 290 PRO PRO A . n A 1 264 ILE 264 291 291 ILE ILE A . n A 1 265 GLY 265 292 292 GLY GLY A . n A 1 266 ARG 266 293 293 ARG ARG A . n A 1 267 ASN 267 294 294 ASN ASN A . n A 1 268 VAL 268 295 295 VAL VAL A . n A 1 269 LEU 269 296 296 LEU LEU A . n A 1 270 GLU 270 297 297 GLU GLU A . n A 1 271 LEU 271 298 298 LEU LEU A . n A 1 272 ASN 272 299 299 ASN ASN A . n A 1 273 ASP 273 300 300 ASP ASP A . n A 1 274 VAL 274 301 301 VAL VAL A . n A 1 275 ARG 275 302 302 ARG ARG A . n A 1 276 GLN 276 303 303 GLN GLN A . n A 1 277 SER 277 304 304 SER SER A . n A 1 278 ALA 278 305 305 ALA ALA A . n A 1 279 ASN 279 306 306 ASN ASN A . n A 1 280 TYR 280 307 307 TYR TYR A . n A 1 281 THR 281 308 308 THR THR A . n A 1 282 CYS 282 309 309 CYS CYS A . n A 1 283 VAL 283 310 310 VAL VAL A . n A 1 284 ALA 284 311 311 ALA ALA A . n A 1 285 MET 285 312 312 MET MET A . n A 1 286 SER 286 313 313 SER SER A . n A 1 287 THR 287 314 314 THR THR A . n A 1 288 LEU 288 315 315 LEU LEU A . n A 1 289 GLY 289 316 316 GLY GLY A . n A 1 290 VAL 290 317 317 VAL VAL A . n A 1 291 ILE 291 318 318 ILE ILE A . n A 1 292 GLU 292 319 319 GLU GLU A . n A 1 293 ALA 293 320 320 ALA ALA A . n A 1 294 ILE 294 321 321 ILE ILE A . n A 1 295 ALA 295 322 322 ALA ALA A . n A 1 296 GLN 296 323 323 GLN GLN A . n A 1 297 ILE 297 324 324 ILE ILE A . n A 1 298 THR 298 325 325 THR THR A . n A 1 299 VAL 299 326 326 VAL VAL A . n A 1 300 LYS 300 327 327 LYS LYS A . n A 1 301 ALA 301 328 328 ALA ALA A . n A 1 302 LEU 302 329 329 LEU LEU A . n A 1 303 PRO 303 330 330 PRO PRO A . n A 1 304 LYS 304 331 331 LYS LYS A . n A 1 305 PRO 305 332 332 PRO PRO A . n A 1 306 PRO 306 333 333 PRO PRO A . n A 1 307 GLY 307 334 334 GLY GLY A . n A 1 308 THR 308 335 335 THR THR A . n A 1 309 PRO 309 336 336 PRO PRO A . n A 1 310 VAL 310 337 337 VAL VAL A . n A 1 311 VAL 311 338 338 VAL VAL A . n A 1 312 THR 312 339 339 THR THR A . n A 1 313 GLU 313 340 340 GLU GLU A . n A 1 314 SER 314 341 341 SER SER A . n A 1 315 THR 315 342 342 THR THR A . n A 1 316 ALA 316 343 343 ALA ALA A . n A 1 317 THR 317 344 344 THR THR A . n A 1 318 SER 318 345 345 SER SER A . n A 1 319 ILE 319 346 346 ILE ILE A . n A 1 320 THR 320 347 347 THR THR A . n A 1 321 LEU 321 348 348 LEU LEU A . n A 1 322 THR 322 349 349 THR THR A . n A 1 323 TRP 323 350 350 TRP TRP A . n A 1 324 ASP 324 351 351 ASP ASP A . n A 1 325 SER 325 352 352 SER SER A . n A 1 326 GLY 326 353 353 GLY GLY A . n A 1 327 ASN 327 354 354 ASN ASN A . n A 1 328 PRO 328 355 355 PRO PRO A . n A 1 329 GLU 329 356 356 GLU GLU A . n A 1 330 PRO 330 357 357 PRO PRO A . n A 1 331 VAL 331 358 358 VAL VAL A . n A 1 332 SER 332 359 359 SER SER A . n A 1 333 TYR 333 360 360 TYR TYR A . n A 1 334 TYR 334 361 361 TYR TYR A . n A 1 335 ILE 335 362 362 ILE ILE A . n A 1 336 ILE 336 363 363 ILE ILE A . n A 1 337 GLN 337 364 364 GLN GLN A . n A 1 338 HIS 338 365 365 HIS HIS A . n A 1 339 LYS 339 366 366 LYS LYS A . n A 1 340 PRO 340 367 367 PRO PRO A . n A 1 341 LYS 341 368 368 LYS LYS A . n A 1 342 ASN 342 369 369 ASN ASN A . n A 1 343 SER 343 370 370 SER SER A . n A 1 344 GLU 344 371 371 GLU GLU A . n A 1 345 GLU 345 372 372 GLU GLU A . n A 1 346 PRO 346 373 373 PRO PRO A . n A 1 347 TYR 347 374 374 TYR TYR A . n A 1 348 LYS 348 375 375 LYS LYS A . n A 1 349 GLU 349 376 376 GLU GLU A . n A 1 350 ILE 350 377 377 ILE ILE A . n A 1 351 ASP 351 378 378 ASP ASP A . n A 1 352 GLY 352 379 379 GLY GLY A . n A 1 353 ILE 353 380 380 ILE ILE A . n A 1 354 ALA 354 381 381 ALA ALA A . n A 1 355 THR 355 382 382 THR THR A . n A 1 356 THR 356 383 383 THR THR A . n A 1 357 ARG 357 384 384 ARG ARG A . n A 1 358 TYR 358 385 385 TYR TYR A . n A 1 359 SER 359 386 386 SER SER A . n A 1 360 VAL 360 387 387 VAL VAL A . n A 1 361 ALA 361 388 388 ALA ALA A . n A 1 362 GLY 362 389 389 GLY GLY A . n A 1 363 LEU 363 390 390 LEU LEU A . n A 1 364 SER 364 391 391 SER SER A . n A 1 365 PRO 365 392 392 PRO PRO A . n A 1 366 TYR 366 393 393 TYR TYR A . n A 1 367 SER 367 394 394 SER SER A . n A 1 368 ASP 368 395 395 ASP ASP A . n A 1 369 TYR 369 396 396 TYR TYR A . n A 1 370 GLU 370 397 397 GLU GLU A . n A 1 371 PHE 371 398 398 PHE PHE A . n A 1 372 ARG 372 399 399 ARG ARG A . n A 1 373 VAL 373 400 400 VAL VAL A . n A 1 374 VAL 374 401 401 VAL VAL A . n A 1 375 ALA 375 402 402 ALA ALA A . n A 1 376 VAL 376 403 403 VAL VAL A . n A 1 377 ASN 377 404 404 ASN ASN A . n A 1 378 ASN 378 405 405 ASN ASN A . n A 1 379 ILE 379 406 406 ILE ILE A . n A 1 380 GLY 380 407 407 GLY GLY A . n A 1 381 ARG 381 408 408 ARG ARG A . n A 1 382 GLY 382 409 409 GLY GLY A . n A 1 383 PRO 383 410 410 PRO PRO A . n A 1 384 ALA 384 411 411 ALA ALA A . n A 1 385 SER 385 412 412 SER SER A . n A 1 386 GLU 386 413 413 GLU GLU A . n A 1 387 PRO 387 414 414 PRO PRO A . n A 1 388 VAL 388 415 415 VAL VAL A . n A 1 389 LEU 389 416 416 LEU LEU A . n A 1 390 THR 390 417 417 THR THR A . n A 1 391 GLN 391 418 418 GLN GLN A . n A 1 392 THR 392 419 419 THR THR A . n A 1 393 SER 393 420 420 SER SER A . n A 1 394 GLU 394 421 421 GLU GLU A . n A 1 395 GLN 395 422 422 GLN GLN A . n A 1 396 ALA 396 423 423 ALA ALA A . n A 1 397 PRO 397 424 424 PRO PRO A . n A 1 398 SER 398 425 425 SER SER A . n A 1 399 SER 399 426 426 SER SER A . n A 1 400 ALA 400 427 427 ALA ALA A . n A 1 401 PRO 401 428 428 PRO PRO A . n A 1 402 ARG 402 429 429 ARG ARG A . n A 1 403 ASP 403 430 430 ASP ASP A . n A 1 404 VAL 404 431 431 VAL VAL A . n A 1 405 GLN 405 432 432 GLN GLN A . n A 1 406 ALA 406 433 433 ALA ALA A . n A 1 407 ARG 407 434 434 ARG ARG A . n A 1 408 MET 408 435 435 MET MET A . n A 1 409 LEU 409 436 436 LEU LEU A . n A 1 410 SER 410 437 437 SER SER A . n A 1 411 SER 411 438 438 SER SER A . n A 1 412 THR 412 439 439 THR THR A . n A 1 413 THR 413 440 440 THR THR A . n A 1 414 ILE 414 441 441 ILE ILE A . n A 1 415 LEU 415 442 442 LEU LEU A . n A 1 416 VAL 416 443 443 VAL VAL A . n A 1 417 GLN 417 444 444 GLN GLN A . n A 1 418 TRP 418 445 445 TRP TRP A . n A 1 419 LYS 419 446 446 LYS LYS A . n A 1 420 GLU 420 447 447 GLU GLU A . n A 1 421 PRO 421 448 448 PRO PRO A . n A 1 422 GLU 422 449 449 GLU GLU A . n A 1 423 GLU 423 450 450 GLU GLU A . n A 1 424 PRO 424 451 451 PRO PRO A . n A 1 425 ASN 425 452 452 ASN ASN A . n A 1 426 GLY 426 453 453 GLY GLY A . n A 1 427 GLN 427 454 454 GLN GLN A . n A 1 428 ILE 428 455 455 ILE ILE A . n A 1 429 GLN 429 456 456 GLN GLN A . n A 1 430 GLY 430 457 457 GLY GLY A . n A 1 431 TYR 431 458 458 TYR TYR A . n A 1 432 ARG 432 459 459 ARG ARG A . n A 1 433 VAL 433 460 460 VAL VAL A . n A 1 434 TYR 434 461 461 TYR TYR A . n A 1 435 TYR 435 462 462 TYR TYR A . n A 1 436 THR 436 463 463 THR THR A . n A 1 437 MET 437 464 464 MET MET A . n A 1 438 ASP 438 465 465 ASP ASP A . n A 1 439 PRO 439 466 466 PRO PRO A . n A 1 440 THR 440 467 467 THR THR A . n A 1 441 GLN 441 468 468 GLN GLN A . n A 1 442 HIS 442 469 469 HIS HIS A . n A 1 443 VAL 443 470 470 VAL VAL A . n A 1 444 ASN 444 471 471 ASN ASN A . n A 1 445 ASN 445 472 472 ASN ASN A . n A 1 446 TRP 446 473 473 TRP TRP A . n A 1 447 MET 447 474 474 MET MET A . n A 1 448 LYS 448 475 475 LYS LYS A . n A 1 449 HIS 449 476 476 HIS HIS A . n A 1 450 ASN 450 477 477 ASN ASN A . n A 1 451 VAL 451 478 478 VAL VAL A . n A 1 452 ALA 452 479 479 ALA ALA A . n A 1 453 ASP 453 480 480 ASP ASP A . n A 1 454 SER 454 481 481 SER SER A . n A 1 455 GLN 455 482 482 GLN GLN A . n A 1 456 ILE 456 483 483 ILE ILE A . n A 1 457 THR 457 484 484 THR THR A . n A 1 458 THR 458 485 485 THR THR A . n A 1 459 ILE 459 486 486 ILE ILE A . n A 1 460 GLY 460 487 487 GLY GLY A . n A 1 461 ASN 461 488 488 ASN ASN A . n A 1 462 LEU 462 489 489 LEU LEU A . n A 1 463 VAL 463 490 490 VAL VAL A . n A 1 464 PRO 464 491 491 PRO PRO A . n A 1 465 GLN 465 492 492 GLN GLN A . n A 1 466 LYS 466 493 493 LYS LYS A . n A 1 467 THR 467 494 494 THR THR A . n A 1 468 TYR 468 495 495 TYR TYR A . n A 1 469 SER 469 496 496 SER SER A . n A 1 470 VAL 470 497 497 VAL VAL A . n A 1 471 LYS 471 498 498 LYS LYS A . n A 1 472 VAL 472 499 499 VAL VAL A . n A 1 473 LEU 473 500 500 LEU LEU A . n A 1 474 ALA 474 501 501 ALA ALA A . n A 1 475 PHE 475 502 502 PHE PHE A . n A 1 476 THR 476 503 503 THR THR A . n A 1 477 SER 477 504 504 SER SER A . n A 1 478 ILE 478 505 505 ILE ILE A . n A 1 479 GLY 479 506 506 GLY GLY A . n A 1 480 ASP 480 507 507 ASP ASP A . n A 1 481 GLY 481 508 508 GLY GLY A . n A 1 482 PRO 482 509 509 PRO PRO A . n A 1 483 LEU 483 510 510 LEU LEU A . n A 1 484 SER 484 511 511 SER SER A . n A 1 485 SER 485 512 512 SER SER A . n A 1 486 ASP 486 513 513 ASP ASP A . n A 1 487 ILE 487 514 514 ILE ILE A . n A 1 488 GLN 488 515 515 GLN GLN A . n A 1 489 VAL 489 516 516 VAL VAL A . n A 1 490 ILE 490 517 517 ILE ILE A . n A 1 491 THR 491 518 518 THR THR A . n A 1 492 GLN 492 519 519 GLN GLN A . n A 1 493 THR 493 520 520 THR THR A . n A 1 494 GLY 494 521 521 GLY GLY A . n A 1 495 VAL 495 522 522 VAL VAL A . n A 1 496 PRO 496 523 523 PRO PRO A . n A 1 497 GLY 497 524 524 GLY GLY A . n A 1 498 GLN 498 525 525 GLN GLN A . n A 1 499 PRO 499 526 526 PRO PRO A . n A 1 500 LEU 500 527 527 LEU LEU A . n A 1 501 ASN 501 528 528 ASN ASN A . n A 1 502 PHE 502 529 529 PHE PHE A . n A 1 503 LYS 503 530 530 LYS LYS A . n A 1 504 ALA 504 531 531 ALA ALA A . n A 1 505 GLU 505 532 532 GLU GLU A . n A 1 506 PRO 506 533 533 PRO PRO A . n A 1 507 GLU 507 534 534 GLU GLU A . n A 1 508 SER 508 535 535 SER SER A . n A 1 509 GLU 509 536 536 GLU GLU A . n A 1 510 THR 510 537 537 THR THR A . n A 1 511 SER 511 538 538 SER SER A . n A 1 512 ILE 512 539 539 ILE ILE A . n A 1 513 LEU 513 540 540 LEU LEU A . n A 1 514 LEU 514 541 541 LEU LEU A . n A 1 515 SER 515 542 542 SER SER A . n A 1 516 TRP 516 543 543 TRP TRP A . n A 1 517 THR 517 544 544 THR THR A . n A 1 518 PRO 518 545 545 PRO PRO A . n A 1 519 PRO 519 546 546 PRO PRO A . n A 1 520 ARG 520 547 547 ARG ARG A . n A 1 521 SER 521 548 548 SER SER A . n A 1 522 ASP 522 549 549 ASP ASP A . n A 1 523 THR 523 550 550 THR THR A . n A 1 524 ILE 524 551 551 ILE ILE A . n A 1 525 ALA 525 552 552 ALA ALA A . n A 1 526 SER 526 553 553 SER SER A . n A 1 527 TYR 527 554 554 TYR TYR A . n A 1 528 GLU 528 555 555 GLU GLU A . n A 1 529 LEU 529 556 556 LEU LEU A . n A 1 530 VAL 530 557 557 VAL VAL A . n A 1 531 TYR 531 558 558 TYR TYR A . n A 1 532 ARG 532 559 559 ARG ARG A . n A 1 533 ASP 533 560 560 ASP ASP A . n A 1 534 GLY 534 561 561 GLY GLY A . n A 1 535 ASP 535 562 562 ASP ASP A . n A 1 536 GLN 536 563 563 GLN GLN A . n A 1 537 GLY 537 564 564 GLY GLY A . n A 1 538 GLU 538 565 565 GLU GLU A . n A 1 539 GLU 539 566 566 GLU GLU A . n A 1 540 GLN 540 567 567 GLN GLN A . n A 1 541 ARG 541 568 568 ARG ARG A . n A 1 542 ILE 542 569 569 ILE ILE A . n A 1 543 THR 543 570 570 THR THR A . n A 1 544 ILE 544 571 571 ILE ILE A . n A 1 545 GLU 545 572 572 GLU GLU A . n A 1 546 PRO 546 573 573 PRO PRO A . n A 1 547 GLY 547 574 574 GLY GLY A . n A 1 548 THR 548 575 575 THR THR A . n A 1 549 SER 549 576 576 SER SER A . n A 1 550 TYR 550 577 577 TYR TYR A . n A 1 551 ARG 551 578 578 ARG ARG A . n A 1 552 LEU 552 579 579 LEU LEU A . n A 1 553 GLN 553 580 580 GLN GLN A . n A 1 554 GLY 554 581 581 GLY GLY A . n A 1 555 LEU 555 582 582 LEU LEU A . n A 1 556 LYS 556 583 583 LYS LYS A . n A 1 557 PRO 557 584 584 PRO PRO A . n A 1 558 ASN 558 585 585 ASN ASN A . n A 1 559 SER 559 586 586 SER SER A . n A 1 560 LEU 560 587 587 LEU LEU A . n A 1 561 TYR 561 588 588 TYR TYR A . n A 1 562 TYR 562 589 589 TYR TYR A . n A 1 563 PHE 563 590 590 PHE PHE A . n A 1 564 ARG 564 591 591 ARG ARG A . n A 1 565 LEU 565 592 592 LEU LEU A . n A 1 566 SER 566 593 593 SER SER A . n A 1 567 ALA 567 594 594 ALA ALA A . n A 1 568 ARG 568 595 595 ARG ARG A . n A 1 569 SER 569 596 596 SER SER A . n A 1 570 PRO 570 597 597 PRO PRO A . n A 1 571 GLN 571 598 598 GLN GLN A . n A 1 572 GLY 572 599 599 GLY GLY A . n A 1 573 LEU 573 600 600 LEU LEU A . n A 1 574 GLY 574 601 601 GLY GLY A . n A 1 575 ALA 575 602 602 ALA ALA A . n A 1 576 SER 576 603 603 SER SER A . n A 1 577 THR 577 604 604 THR THR A . n A 1 578 ALA 578 605 605 ALA ALA A . n A 1 579 GLU 579 606 606 GLU GLU A . n A 1 580 ILE 580 607 607 ILE ILE A . n A 1 581 SER 581 608 608 SER SER A . n A 1 582 ALA 582 609 609 ALA ALA A . n A 1 583 ARG 583 610 610 ARG ARG A . n A 1 584 THR 584 611 611 THR THR A . n A 1 585 MET 585 612 612 MET MET A . n A 1 586 GLN 586 613 ? ? ? A . n A 1 587 SER 587 614 ? ? ? A . n A 1 588 MET 588 615 ? ? ? A . n A 1 589 PHE 589 616 ? ? ? A . n A 1 590 ALA 590 617 ? ? ? A . n A 1 591 LYS 591 618 ? ? ? A . n A 1 592 ASN 592 619 ? ? ? A . n A 1 593 PHE 593 620 ? ? ? A . n A 1 594 HIS 594 621 ? ? ? A . n A 1 595 VAL 595 622 ? ? ? A . n A 1 596 LYS 596 623 ? ? ? A . n A 1 597 ALA 597 624 ? ? ? A . n A 1 598 VAL 598 625 ? ? ? A . n A 1 599 MET 599 626 ? ? ? A . n A 1 600 LYS 600 627 ? ? ? A . n A 1 601 THR 601 628 ? ? ? A . n A 1 602 SER 602 629 ? ? ? A . n A 1 603 VAL 603 630 ? ? ? A . n A 1 604 LEU 604 631 ? ? ? A . n A 1 605 LEU 605 632 ? ? ? A . n A 1 606 SER 606 633 ? ? ? A . n A 1 607 TRP 607 634 ? ? ? A . n A 1 608 GLU 608 635 ? ? ? A . n A 1 609 ILE 609 636 ? ? ? A . n A 1 610 PRO 610 637 ? ? ? A . n A 1 611 GLU 611 638 ? ? ? A . n A 1 612 ASN 612 639 ? ? ? A . n A 1 613 TYR 613 640 ? ? ? A . n A 1 614 ASN 614 641 ? ? ? A . n A 1 615 SER 615 642 ? ? ? A . n A 1 616 ALA 616 643 ? ? ? A . n A 1 617 MET 617 644 ? ? ? A . n A 1 618 PRO 618 645 ? ? ? A . n A 1 619 PHE 619 646 ? ? ? A . n A 1 620 LYS 620 647 ? ? ? A . n A 1 621 ILE 621 648 ? ? ? A . n A 1 622 LEU 622 649 ? ? ? A . n A 1 623 TYR 623 650 ? ? ? A . n A 1 624 ASP 624 651 ? ? ? A . n A 1 625 ASP 625 652 ? ? ? A . n A 1 626 GLY 626 653 ? ? ? A . n A 1 627 LYS 627 654 ? ? ? A . n A 1 628 MET 628 655 ? ? ? A . n A 1 629 VAL 629 656 ? ? ? A . n A 1 630 GLU 630 657 ? ? ? A . n A 1 631 GLU 631 658 ? ? ? A . n A 1 632 VAL 632 659 ? ? ? A . n A 1 633 ASP 633 660 ? ? ? A . n A 1 634 GLY 634 661 ? ? ? A . n A 1 635 ARG 635 662 ? ? ? A . n A 1 636 ALA 636 663 ? ? ? A . n A 1 637 THR 637 664 ? ? ? A . n A 1 638 GLN 638 665 ? ? ? A . n A 1 639 LYS 639 666 ? ? ? A . n A 1 640 LEU 640 667 ? ? ? A . n A 1 641 ILE 641 668 ? ? ? A . n A 1 642 VAL 642 669 ? ? ? A . n A 1 643 ASN 643 670 ? ? ? A . n A 1 644 LEU 644 671 ? ? ? A . n A 1 645 LYS 645 672 ? ? ? A . n A 1 646 PRO 646 673 ? ? ? A . n A 1 647 GLU 647 674 ? ? ? A . n A 1 648 LYS 648 675 ? ? ? A . n A 1 649 SER 649 676 ? ? ? A . n A 1 650 TYR 650 677 ? ? ? A . n A 1 651 SER 651 678 ? ? ? A . n A 1 652 PHE 652 679 ? ? ? A . n A 1 653 VAL 653 680 ? ? ? A . n A 1 654 LEU 654 681 ? ? ? A . n A 1 655 THR 655 682 ? ? ? A . n A 1 656 ASN 656 683 ? ? ? A . n A 1 657 ARG 657 684 ? ? ? A . n A 1 658 GLY 658 685 ? ? ? A . n A 1 659 ASN 659 686 ? ? ? A . n A 1 660 SER 660 687 ? ? ? A . n A 1 661 ALA 661 688 ? ? ? A . n A 1 662 GLY 662 689 ? ? ? A . n A 1 663 GLY 663 690 ? ? ? A . n A 1 664 LEU 664 691 ? ? ? A . n A 1 665 GLN 665 692 ? ? ? A . n A 1 666 HIS 666 693 ? ? ? A . n A 1 667 ARG 667 694 ? ? ? A . n A 1 668 VAL 668 695 ? ? ? A . n A 1 669 THR 669 696 ? ? ? A . n A 1 670 ALA 670 697 ? ? ? A . n A 1 671 LYS 671 698 ? ? ? A . n A 1 672 THR 672 699 ? ? ? A . n A 1 673 ALA 673 700 ? ? ? A . n A 1 674 PRO 674 701 ? ? ? A . n A 1 675 ASP 675 702 ? ? ? A . n A 1 676 VAL 676 703 ? ? ? A . n A 1 677 LEU 677 704 ? ? ? A . n A 1 678 ARG 678 705 ? ? ? A . n A 1 679 THR 679 706 ? ? ? A . n A 1 680 LYS 680 707 ? ? ? A . n A 1 681 PRO 681 708 ? ? ? A . n A 1 682 ALA 682 709 ? ? ? A . n A 1 683 PHE 683 710 ? ? ? A . n A 1 684 ILE 684 711 ? ? ? A . n A 1 685 GLY 685 712 ? ? ? A . n A 1 686 LYS 686 713 ? ? ? A . n A 1 687 THR 687 714 ? ? ? A . n A 1 688 ASN 688 715 ? ? ? A . n A 1 689 LEU 689 716 ? ? ? A . n A 1 690 ASP 690 717 ? ? ? A . n A 1 691 GLY 691 718 ? ? ? A . n A 1 692 MET 692 719 ? ? ? A . n A 1 693 ILE 693 720 ? ? ? A . n A 1 694 THR 694 721 ? ? ? A . n A 1 695 VAL 695 722 ? ? ? A . n A 1 696 GLN 696 723 ? ? ? A . n A 1 697 LEU 697 724 ? ? ? A . n A 1 698 PRO 698 725 ? ? ? A . n A 1 699 ASP 699 726 ? ? ? A . n A 1 700 VAL 700 727 ? ? ? A . n A 1 701 PRO 701 728 ? ? ? A . n A 1 702 ALA 702 729 ? ? ? A . n A 1 703 ASN 703 730 ? ? ? A . n A 1 704 GLU 704 731 ? ? ? A . n A 1 705 ASN 705 732 ? ? ? A . n A 1 706 ILE 706 733 ? ? ? A . n A 1 707 LYS 707 734 ? ? ? A . n A 1 708 GLY 708 735 ? ? ? A . n A 1 709 TYR 709 736 ? ? ? A . n A 1 710 TYR 710 737 ? ? ? A . n A 1 711 ILE 711 738 ? ? ? A . n A 1 712 ILE 712 739 ? ? ? A . n A 1 713 ILE 713 740 ? ? ? A . n A 1 714 VAL 714 741 ? ? ? A . n A 1 715 PRO 715 742 ? ? ? A . n A 1 716 LEU 716 743 ? ? ? A . n A 1 717 LYS 717 744 ? ? ? A . n A 1 718 LYS 718 745 ? ? ? A . n A 1 719 SER 719 746 ? ? ? A . n A 1 720 ARG 720 747 ? ? ? A . n A 1 721 GLY 721 748 ? ? ? A . n A 1 722 LYS 722 749 ? ? ? A . n A 1 723 PHE 723 750 ? ? ? A . n A 1 724 ILE 724 751 ? ? ? A . n A 1 725 LYS 725 752 ? ? ? A . n A 1 726 PRO 726 753 ? ? ? A . n A 1 727 TRP 727 754 ? ? ? A . n A 1 728 GLU 728 755 ? ? ? A . n A 1 729 SER 729 756 ? ? ? A . n A 1 730 PRO 730 757 ? ? ? A . n A 1 731 ASP 731 758 ? ? ? A . n A 1 732 GLU 732 759 ? ? ? A . n A 1 733 MET 733 760 ? ? ? A . n A 1 734 GLU 734 761 ? ? ? A . n A 1 735 LEU 735 762 ? ? ? A . n A 1 736 ASP 736 763 ? ? ? A . n A 1 737 GLU 737 764 ? ? ? A . n A 1 738 LEU 738 765 ? ? ? A . n A 1 739 LEU 739 766 ? ? ? A . n A 1 740 LYS 740 767 ? ? ? A . n A 1 741 GLU 741 768 ? ? ? A . n A 1 742 ILE 742 769 ? ? ? A . n A 1 743 SER 743 770 ? ? ? A . n A 1 744 ARG 744 771 ? ? ? A . n A 1 745 LYS 745 772 ? ? ? A . n A 1 746 ARG 746 773 ? ? ? A . n A 1 747 ARG 747 774 ? ? ? A . n A 1 748 SER 748 775 ? ? ? A . n A 1 749 ILE 749 776 ? ? ? A . n A 1 750 ARG 750 777 ? ? ? A . n A 1 751 TYR 751 778 ? ? ? A . n A 1 752 GLY 752 779 ? ? ? A . n A 1 753 ARG 753 780 ? ? ? A . n A 1 754 GLU 754 781 ? ? ? A . n A 1 755 VAL 755 782 ? ? ? A . n A 1 756 GLU 756 783 ? ? ? A . n A 1 757 LEU 757 784 ? ? ? A . n A 1 758 LYS 758 785 ? ? ? A . n A 1 759 PRO 759 786 ? ? ? A . n A 1 760 TYR 760 787 ? ? ? A . n A 1 761 ILE 761 788 ? ? ? A . n A 1 762 ALA 762 789 ? ? ? A . n A 1 763 ALA 763 790 ? ? ? A . n A 1 764 HIS 764 791 ? ? ? A . n A 1 765 PHE 765 792 ? ? ? A . n A 1 766 ASP 766 793 ? ? ? A . n A 1 767 VAL 767 794 ? ? ? A . n A 1 768 LEU 768 795 ? ? ? A . n A 1 769 PRO 769 796 ? ? ? A . n A 1 770 THR 770 797 ? ? ? A . n A 1 771 GLU 771 798 ? ? ? A . n A 1 772 PHE 772 799 ? ? ? A . n A 1 773 THR 773 800 ? ? ? A . n A 1 774 LEU 774 801 ? ? ? A . n A 1 775 GLY 775 802 ? ? ? A . n A 1 776 ASP 776 803 ? ? ? A . n A 1 777 ASP 777 804 ? ? ? A . n A 1 778 LYS 778 805 ? ? ? A . n A 1 779 HIS 779 806 ? ? ? A . n A 1 780 TYR 780 807 ? ? ? A . n A 1 781 GLY 781 808 ? ? ? A . n A 1 782 GLY 782 809 ? ? ? A . n A 1 783 PHE 783 810 ? ? ? A . n A 1 784 THR 784 811 ? ? ? A . n A 1 785 ASN 785 812 ? ? ? A . n A 1 786 LYS 786 813 ? ? ? A . n A 1 787 GLN 787 814 ? ? ? A . n A 1 788 LEU 788 815 ? ? ? A . n A 1 789 GLN 789 816 ? ? ? A . n A 1 790 SER 790 817 ? ? ? A . n A 1 791 GLY 791 818 ? ? ? A . n A 1 792 GLN 792 819 ? ? ? A . n A 1 793 GLU 793 820 ? ? ? A . n A 1 794 TYR 794 821 ? ? ? A . n A 1 795 VAL 795 822 ? ? ? A . n A 1 796 PHE 796 823 ? ? ? A . n A 1 797 PHE 797 824 ? ? ? A . n A 1 798 VAL 798 825 ? ? ? A . n A 1 799 LEU 799 826 ? ? ? A . n A 1 800 ALA 800 827 ? ? ? A . n A 1 801 VAL 801 828 ? ? ? A . n A 1 802 MET 802 829 ? ? ? A . n A 1 803 ASP 803 830 ? ? ? A . n A 1 804 HIS 804 831 ? ? ? A . n A 1 805 ALA 805 832 ? ? ? A . n A 1 806 GLU 806 833 ? ? ? A . n A 1 807 SER 807 834 ? ? ? A . n A 1 808 LYS 808 835 ? ? ? A . n A 1 809 MET 809 836 ? ? ? A . n A 1 810 TYR 810 837 ? ? ? A . n A 1 811 ALA 811 838 ? ? ? A . n A 1 812 THR 812 839 ? ? ? A . n A 1 813 SER 813 840 ? ? ? A . n A 1 814 PRO 814 841 ? ? ? A . n A 1 815 TYR 815 842 ? ? ? A . n A 1 816 SER 816 843 ? ? ? A . n A 1 817 ASP 817 844 ? ? ? A . n A 1 818 PRO 818 845 ? ? ? A . n A 1 819 VAL 819 846 ? ? ? A . n A 1 820 VAL 820 847 ? ? ? A . n A 1 821 SER 821 848 ? ? ? A . n A 1 822 MET 822 849 ? ? ? A . n A 1 823 ASP 823 850 ? ? ? A . n A 1 824 LEU 824 851 ? ? ? A . n A 1 825 ASP 825 852 ? ? ? A . n A 1 826 PRO 826 853 ? ? ? A . n A 1 827 GLN 827 854 ? ? ? A . n A 1 828 PRO 828 855 ? ? ? A . n A 1 829 ILE 829 856 ? ? ? A . n A 1 830 THR 830 857 ? ? ? A . n A 1 831 ASP 831 858 ? ? ? A . n A 1 832 GLU 832 859 ? ? ? A . n A 1 833 GLU 833 860 ? ? ? A . n A 1 834 GLU 834 861 ? ? ? A . n A 1 835 LYS 835 862 ? ? ? A . n A 1 836 HIS 836 863 ? ? ? A . n A 1 837 HIS 837 864 ? ? ? A . n A 1 838 HIS 838 865 ? ? ? A . n A 1 839 HIS 839 866 ? ? ? A . n A 1 840 HIS 840 867 ? ? ? A . n A 1 841 HIS 841 868 ? ? ? A . n B 2 1 ALA 1 12 ? ? ? B . n B 2 2 GLN 2 13 ? ? ? B . n B 2 3 PRO 3 14 ? ? ? B . n B 2 4 ALA 4 15 ? ? ? B . n B 2 5 ALA 5 16 ? ? ? B . n B 2 6 ARG 6 17 ? ? ? B . n B 2 7 ASP 7 18 ? ? ? B . n B 2 8 LEU 8 19 ? ? ? B . n B 2 9 LYS 9 20 ? ? ? B . n B 2 10 VAL 10 21 ? ? ? B . n B 2 11 VAL 11 22 ? ? ? B . n B 2 12 THR 12 23 ? ? ? B . n B 2 13 LYS 13 24 ? ? ? B . n B 2 14 ARG 14 25 ? ? ? B . n B 2 15 GLY 15 26 ? ? ? B . n B 2 16 SER 16 27 ? ? ? B . n B 2 17 ALA 17 28 ? ? ? B . n B 2 18 ASP 18 29 ? ? ? B . n B 2 19 GLY 19 30 ? ? ? B . n B 2 20 CYS 20 31 31 CYS CYS B . n B 2 21 THR 21 32 32 THR THR B . n B 2 22 ASP 22 33 33 ASP ASP B . n B 2 23 TRP 23 34 34 TRP TRP B . n B 2 24 SER 24 35 35 SER SER B . n B 2 25 VAL 25 36 36 VAL VAL B . n B 2 26 ASP 26 37 37 ASP ASP B . n B 2 27 ILE 27 38 38 ILE ILE B . n B 2 28 LYS 28 39 39 LYS LYS B . n B 2 29 LYS 29 40 40 LYS LYS B . n B 2 30 TYR 30 41 41 TYR TYR B . n B 2 31 GLN 31 42 42 GLN GLN B . n B 2 32 VAL 32 43 43 VAL VAL B . n B 2 33 LEU 33 44 44 LEU LEU B . n B 2 34 VAL 34 45 45 VAL VAL B . n B 2 35 GLY 35 46 46 GLY GLY B . n B 2 36 GLU 36 47 47 GLU GLU B . n B 2 37 PRO 37 48 48 PRO PRO B . n B 2 38 VAL 38 49 49 VAL VAL B . n B 2 39 ARG 39 50 50 ARG ARG B . n B 2 40 ILE 40 51 51 ILE ILE B . n B 2 41 LYS 41 52 52 LYS LYS B . n B 2 42 CYS 42 53 53 CYS CYS B . n B 2 43 ALA 43 54 54 ALA ALA B . n B 2 44 LEU 44 55 55 LEU LEU B . n B 2 45 PHE 45 56 56 PHE PHE B . n B 2 46 TYR 46 57 57 TYR TYR B . n B 2 47 GLY 47 58 58 GLY GLY B . n B 2 48 TYR 48 59 59 TYR TYR B . n B 2 49 ILE 49 60 60 ILE ILE B . n B 2 50 ARG 50 61 61 ARG ARG B . n B 2 51 THR 51 62 62 THR THR B . n B 2 52 ASN 52 63 63 ASN ASN B . n B 2 53 TYR 53 64 64 TYR TYR B . n B 2 54 SER 54 65 65 SER SER B . n B 2 55 LEU 55 66 66 LEU LEU B . n B 2 56 ALA 56 67 67 ALA ALA B . n B 2 57 GLN 57 68 68 GLN GLN B . n B 2 58 SER 58 69 69 SER SER B . n B 2 59 ALA 59 70 70 ALA ALA B . n B 2 60 GLY 60 71 71 GLY GLY B . n B 2 61 LEU 61 72 72 LEU LEU B . n B 2 62 SER 62 73 73 SER SER B . n B 2 63 LEU 63 74 74 LEU LEU B . n B 2 64 MET 64 75 75 MET MET B . n B 2 65 TRP 65 76 76 TRP TRP B . n B 2 66 TYR 66 77 77 TYR TYR B . n B 2 67 LYS 67 78 78 LYS LYS B . n B 2 68 SER 68 79 79 SER SER B . n B 2 69 SER 69 80 80 SER SER B . n B 2 70 GLY 70 81 81 GLY GLY B . n B 2 71 PRO 71 82 82 PRO PRO B . n B 2 72 GLY 72 83 83 GLY GLY B . n B 2 73 ASP 73 84 84 ASP ASP B . n B 2 74 PHE 74 85 85 PHE PHE B . n B 2 75 GLU 75 86 86 GLU GLU B . n B 2 76 GLU 76 87 87 GLU GLU B . n B 2 77 PRO 77 88 88 PRO PRO B . n B 2 78 ILE 78 89 89 ILE ILE B . n B 2 79 ALA 79 90 90 ALA ALA B . n B 2 80 PHE 80 91 91 PHE PHE B . n B 2 81 ASP 81 92 92 ASP ASP B . n B 2 82 GLY 82 93 93 GLY GLY B . n B 2 83 SER 83 94 94 SER SER B . n B 2 84 ARG 84 95 95 ARG ARG B . n B 2 85 MET 85 96 96 MET MET B . n B 2 86 SER 86 97 97 SER SER B . n B 2 87 LYS 87 98 98 LYS LYS B . n B 2 88 GLU 88 99 99 GLU GLU B . n B 2 89 GLU 89 100 100 GLU GLU B . n B 2 90 ASP 90 101 101 ASP ASP B . n B 2 91 SER 91 102 102 SER SER B . n B 2 92 ILE 92 103 103 ILE ILE B . n B 2 93 TRP 93 104 104 TRP TRP B . n B 2 94 PHE 94 105 105 PHE PHE B . n B 2 95 ARG 95 106 106 ARG ARG B . n B 2 96 PRO 96 107 107 PRO PRO B . n B 2 97 THR 97 108 108 THR THR B . n B 2 98 LEU 98 109 109 LEU LEU B . n B 2 99 LEU 99 110 110 LEU LEU B . n B 2 100 GLN 100 111 111 GLN GLN B . n B 2 101 ASP 101 112 112 ASP ASP B . n B 2 102 SER 102 113 113 SER SER B . n B 2 103 GLY 103 114 114 GLY GLY B . n B 2 104 LEU 104 115 115 LEU LEU B . n B 2 105 TYR 105 116 116 TYR TYR B . n B 2 106 ALA 106 117 117 ALA ALA B . n B 2 107 CYS 107 118 118 CYS CYS B . n B 2 108 VAL 108 119 119 VAL VAL B . n B 2 109 ILE 109 120 120 ILE ILE B . n B 2 110 ARG 110 121 121 ARG ARG B . n B 2 111 ASN 111 122 122 ASN ASN B . n B 2 112 SER 112 123 123 SER SER B . n B 2 113 THR 113 124 124 THR THR B . n B 2 114 TYR 114 125 125 TYR TYR B . n B 2 115 CYS 115 126 126 CYS CYS B . n B 2 116 MET 116 127 127 MET MET B . n B 2 117 LYS 117 128 128 LYS LYS B . n B 2 118 VAL 118 129 129 VAL VAL B . n B 2 119 SER 119 130 130 SER SER B . n B 2 120 ILE 120 131 131 ILE ILE B . n B 2 121 SER 121 132 132 SER SER B . n B 2 122 LEU 122 133 133 LEU LEU B . n B 2 123 THR 123 134 134 THR THR B . n B 2 124 VAL 124 135 135 VAL VAL B . n B 2 125 GLY 125 136 136 GLY GLY B . n B 2 126 GLU 126 137 137 GLU GLU B . n B 2 127 ASN 127 138 138 ASN ASN B . n B 2 128 ASP 128 139 139 ASP ASP B . n B 2 129 THR 129 140 140 THR THR B . n B 2 130 GLY 130 141 141 GLY GLY B . n B 2 131 LEU 131 142 142 LEU LEU B . n B 2 132 CYS 132 143 143 CYS CYS B . n B 2 133 TYR 133 144 144 TYR TYR B . n B 2 134 ASN 134 145 145 ASN ASN B . n B 2 135 SER 135 146 146 SER SER B . n B 2 136 LYS 136 147 147 LYS LYS B . n B 2 137 MET 137 148 148 MET MET B . n B 2 138 LYS 138 149 149 LYS LYS B . n B 2 139 TYR 139 150 150 TYR TYR B . n B 2 140 PHE 140 151 151 PHE PHE B . n B 2 141 GLU 141 152 152 GLU GLU B . n B 2 142 LYS 142 153 153 LYS LYS B . n B 2 143 ALA 143 154 154 ALA ALA B . n B 2 144 GLU 144 155 155 GLU GLU B . n B 2 145 LEU 145 156 156 LEU LEU B . n B 2 146 SER 146 157 157 SER SER B . n B 2 147 LYS 147 158 158 LYS LYS B . n B 2 148 SER 148 159 159 SER SER B . n B 2 149 LYS 149 160 160 LYS LYS B . n B 2 150 GLU 150 161 161 GLU GLU B . n B 2 151 ILE 151 162 162 ILE ILE B . n B 2 152 SER 152 163 163 SER SER B . n B 2 153 CYS 153 164 164 CYS CYS B . n B 2 154 ARG 154 165 165 ARG ARG B . n B 2 155 ASP 155 166 166 ASP ASP B . n B 2 156 ILE 156 167 167 ILE ILE B . n B 2 157 GLU 157 168 168 GLU GLU B . n B 2 158 ASP 158 169 169 ASP ASP B . n B 2 159 PHE 159 170 170 PHE PHE B . n B 2 160 LEU 160 171 171 LEU LEU B . n B 2 161 LEU 161 172 ? ? ? B . n B 2 162 PRO 162 173 ? ? ? B . n B 2 163 THR 163 174 ? ? ? B . n B 2 164 ARG 164 175 ? ? ? B . n B 2 165 GLU 165 176 176 GLU GLU B . n B 2 166 PRO 166 177 177 PRO PRO B . n B 2 167 GLU 167 178 178 GLU GLU B . n B 2 168 ILE 168 179 179 ILE ILE B . n B 2 169 LEU 169 180 180 LEU LEU B . n B 2 170 TRP 170 181 181 TRP TRP B . n B 2 171 TYR 171 182 182 TYR TYR B . n B 2 172 LYS 172 183 183 LYS LYS B . n B 2 173 GLU 173 184 184 GLU GLU B . n B 2 174 CYS 174 185 185 CYS CYS B . n B 2 175 ARG 175 186 186 ARG ARG B . n B 2 176 THR 176 187 187 THR THR B . n B 2 177 LYS 177 188 188 LYS LYS B . n B 2 178 ALA 178 189 189 ALA ALA B . n B 2 179 TRP 179 190 190 TRP TRP B . n B 2 180 ARG 180 191 191 ARG ARG B . n B 2 181 PRO 181 192 192 PRO PRO B . n B 2 182 SER 182 193 193 SER SER B . n B 2 183 ILE 183 194 194 ILE ILE B . n B 2 184 VAL 184 195 195 VAL VAL B . n B 2 185 PHE 185 196 196 PHE PHE B . n B 2 186 LYS 186 197 197 LYS LYS B . n B 2 187 ARG 187 198 198 ARG ARG B . n B 2 188 ASP 188 199 199 ASP ASP B . n B 2 189 THR 189 200 200 THR THR B . n B 2 190 LEU 190 201 201 LEU LEU B . n B 2 191 LEU 191 202 202 LEU LEU B . n B 2 192 ILE 192 203 203 ILE ILE B . n B 2 193 LYS 193 204 204 LYS LYS B . n B 2 194 GLU 194 205 205 GLU GLU B . n B 2 195 VAL 195 206 206 VAL VAL B . n B 2 196 LYS 196 207 207 LYS LYS B . n B 2 197 GLU 197 208 208 GLU GLU B . n B 2 198 ASP 198 209 209 ASP ASP B . n B 2 199 ASP 199 210 210 ASP ASP B . n B 2 200 ILE 200 211 211 ILE ILE B . n B 2 201 GLY 201 212 212 GLY GLY B . n B 2 202 ASN 202 213 213 ASN ASN B . n B 2 203 TYR 203 214 214 TYR TYR B . n B 2 204 THR 204 215 215 THR THR B . n B 2 205 CYS 205 216 216 CYS CYS B . n B 2 206 GLU 206 217 217 GLU GLU B . n B 2 207 LEU 207 218 218 LEU LEU B . n B 2 208 LYS 208 219 219 LYS LYS B . n B 2 209 TYR 209 220 220 TYR TYR B . n B 2 210 GLY 210 221 221 GLY GLY B . n B 2 211 GLY 211 222 222 GLY GLY B . n B 2 212 PHE 212 223 223 PHE PHE B . n B 2 213 VAL 213 224 224 VAL VAL B . n B 2 214 VAL 214 225 225 VAL VAL B . n B 2 215 ARG 215 226 226 ARG ARG B . n B 2 216 ARG 216 227 227 ARG ARG B . n B 2 217 THR 217 228 228 THR THR B . n B 2 218 THR 218 229 229 THR THR B . n B 2 219 GLU 219 230 230 GLU GLU B . n B 2 220 LEU 220 231 231 LEU LEU B . n B 2 221 THR 221 232 232 THR THR B . n B 2 222 VAL 222 233 233 VAL VAL B . n B 2 223 THR 223 234 234 THR THR B . n B 2 224 ALA 224 235 235 ALA ALA B . n B 2 225 PRO 225 236 236 PRO PRO B . n B 2 226 LEU 226 237 237 LEU LEU B . n B 2 227 THR 227 238 238 THR THR B . n B 2 228 ASP 228 239 239 ASP ASP B . n B 2 229 LYS 229 240 240 LYS LYS B . n B 2 230 PRO 230 241 241 PRO PRO B . n B 2 231 PRO 231 242 242 PRO PRO B . n B 2 232 LYS 232 243 243 LYS LYS B . n B 2 233 LEU 233 244 244 LEU LEU B . n B 2 234 LEU 234 245 245 LEU LEU B . n B 2 235 TYR 235 246 246 TYR TYR B . n B 2 236 PRO 236 247 247 PRO PRO B . n B 2 237 MET 237 248 248 MET MET B . n B 2 238 GLU 238 249 249 GLU GLU B . n B 2 239 SER 239 250 250 SER SER B . n B 2 240 LYS 240 251 251 LYS LYS B . n B 2 241 LEU 241 252 252 LEU LEU B . n B 2 242 THR 242 253 253 THR THR B . n B 2 243 VAL 243 254 254 VAL VAL B . n B 2 244 GLN 244 255 255 GLN GLN B . n B 2 245 GLU 245 256 256 GLU GLU B . n B 2 246 THR 246 257 257 THR THR B . n B 2 247 GLN 247 258 258 GLN GLN B . n B 2 248 LEU 248 259 259 LEU LEU B . n B 2 249 GLY 249 260 260 GLY GLY B . n B 2 250 GLY 250 261 261 GLY GLY B . n B 2 251 SER 251 262 262 SER SER B . n B 2 252 ALA 252 263 263 ALA ALA B . n B 2 253 ASN 253 264 264 ASN ASN B . n B 2 254 LEU 254 265 265 LEU LEU B . n B 2 255 THR 255 266 266 THR THR B . n B 2 256 CYS 256 267 267 CYS CYS B . n B 2 257 ARG 257 268 268 ARG ARG B . n B 2 258 ALA 258 269 269 ALA ALA B . n B 2 259 PHE 259 270 270 PHE PHE B . n B 2 260 PHE 260 271 271 PHE PHE B . n B 2 261 GLY 261 272 272 GLY GLY B . n B 2 262 TYR 262 273 273 TYR TYR B . n B 2 263 SER 263 274 274 SER SER B . n B 2 264 GLY 264 275 275 GLY GLY B . n B 2 265 ASP 265 276 276 ASP ASP B . n B 2 266 VAL 266 277 277 VAL VAL B . n B 2 267 SER 267 278 278 SER SER B . n B 2 268 PRO 268 279 279 PRO PRO B . n B 2 269 LEU 269 280 280 LEU LEU B . n B 2 270 ILE 270 281 281 ILE ILE B . n B 2 271 TYR 271 282 282 TYR TYR B . n B 2 272 TRP 272 283 283 TRP TRP B . n B 2 273 MET 273 284 284 MET MET B . n B 2 274 LYS 274 285 285 LYS LYS B . n B 2 275 GLY 275 286 286 GLY GLY B . n B 2 276 GLU 276 287 287 GLU GLU B . n B 2 277 LYS 277 288 288 LYS LYS B . n B 2 278 PHE 278 289 289 PHE PHE B . n B 2 279 ILE 279 290 290 ILE ILE B . n B 2 280 GLU 280 291 291 GLU GLU B . n B 2 281 ASP 281 292 292 ASP ASP B . n B 2 282 LEU 282 293 293 LEU LEU B . n B 2 283 ASP 283 294 294 ASP ASP B . n B 2 284 GLU 284 295 295 GLU GLU B . n B 2 285 ASN 285 296 296 ASN ASN B . n B 2 286 ARG 286 297 297 ARG ARG B . n B 2 287 VAL 287 298 298 VAL VAL B . n B 2 288 TRP 288 299 299 TRP TRP B . n B 2 289 GLU 289 300 300 GLU GLU B . n B 2 290 SER 290 301 301 SER SER B . n B 2 291 ASP 291 302 302 ASP ASP B . n B 2 292 ILE 292 303 303 ILE ILE B . n B 2 293 ARG 293 304 304 ARG ARG B . n B 2 294 ILE 294 305 305 ILE ILE B . n B 2 295 LEU 295 306 306 LEU LEU B . n B 2 296 LYS 296 307 307 LYS LYS B . n B 2 297 GLU 297 308 308 GLU GLU B . n B 2 298 HIS 298 309 309 HIS HIS B . n B 2 299 LEU 299 310 310 LEU LEU B . n B 2 300 GLY 300 311 311 GLY GLY B . n B 2 301 GLU 301 312 312 GLU GLU B . n B 2 302 GLN 302 313 313 GLN GLN B . n B 2 303 GLU 303 314 314 GLU GLU B . n B 2 304 VAL 304 315 315 VAL VAL B . n B 2 305 SER 305 316 316 SER SER B . n B 2 306 ILE 306 317 317 ILE ILE B . n B 2 307 SER 307 318 318 SER SER B . n B 2 308 LEU 308 319 319 LEU LEU B . n B 2 309 ILE 309 320 320 ILE ILE B . n B 2 310 VAL 310 321 321 VAL VAL B . n B 2 311 ASP 311 322 322 ASP ASP B . n B 2 312 SER 312 323 323 SER SER B . n B 2 313 VAL 313 324 324 VAL VAL B . n B 2 314 GLU 314 325 325 GLU GLU B . n B 2 315 GLU 315 326 326 GLU GLU B . n B 2 316 GLY 316 327 327 GLY GLY B . n B 2 317 ASP 317 328 328 ASP ASP B . n B 2 318 LEU 318 329 329 LEU LEU B . n B 2 319 GLY 319 330 330 GLY GLY B . n B 2 320 ASN 320 331 331 ASN ASN B . n B 2 321 TYR 321 332 332 TYR TYR B . n B 2 322 SER 322 333 333 SER SER B . n B 2 323 CYS 323 334 334 CYS CYS B . n B 2 324 TYR 324 335 335 TYR TYR B . n B 2 325 VAL 325 336 336 VAL VAL B . n B 2 326 GLU 326 337 337 GLU GLU B . n B 2 327 ASN 327 338 338 ASN ASN B . n B 2 328 GLY 328 339 339 GLY GLY B . n B 2 329 ASN 329 340 340 ASN ASN B . n B 2 330 GLY 330 341 341 GLY GLY B . n B 2 331 ARG 331 342 342 ARG ARG B . n B 2 332 ARG 332 343 343 ARG ARG B . n B 2 333 HIS 333 344 344 HIS HIS B . n B 2 334 ALA 334 345 345 ALA ALA B . n B 2 335 SER 335 346 346 SER SER B . n B 2 336 VAL 336 347 347 VAL VAL B . n B 2 337 LEU 337 348 348 LEU LEU B . n B 2 338 LEU 338 349 349 LEU LEU B . n B 2 339 HIS 339 350 350 HIS HIS B . n B 2 340 LYS 340 351 351 LYS LYS B . n B 2 341 ARG 341 352 352 ARG ARG B . n B 2 342 LYS 342 353 353 LYS ALA B . n B 2 343 HIS 343 354 354 HIS ALA B . n B 2 344 HIS 344 355 355 HIS HIS B . n B 2 345 HIS 345 356 356 HIS HIS B . n B 2 346 HIS 346 357 357 HIS HIS B . n B 2 347 HIS 347 358 358 HIS HIS B . n B 2 348 HIS 348 359 ? ? ? B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 3 NAG 1 401 1221 NAG NAG B . D 3 NAG 1 402 1381 NAG NAG B . E 3 NAG 1 403 2131 NAG NAG B . F 3 NAG 2 404 2132 NAG NAG B . G 3 NAG 1 405 2641 NAG NAG B . H 3 NAG 2 406 2642 NAG NAG B . I 4 BMA 3 407 2643 BMA BMA B . J 5 MAN 4 408 2644 MAN MAN B . K 5 MAN 5 409 2645 MAN MAN B . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 5210 ? 1 MORE 14 ? 1 'SSA (A^2)' 50150 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # _pdbx_audit_revision_history.ordinal 1 _pdbx_audit_revision_history.data_content_type 'Structure model' _pdbx_audit_revision_history.major_revision 1 _pdbx_audit_revision_history.minor_revision 0 _pdbx_audit_revision_history.revision_date 2015-05-06 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(phenix.refine: 1.8.2_1309)' 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 4 # _pdbx_entry_details.compound_details ? _pdbx_entry_details.entry_id 4YH7 _pdbx_entry_details.nonpolymer_details ? _pdbx_entry_details.sequence_details 'SEQUENCE OF THE CHAIN A WAS BASED ON ISOFORM 12 OF DATABASE UNP Q64487' _pdbx_entry_details.source_details ? # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 NH2 A ARG 98 ? ? OE2 B GLU 291 ? ? 2.09 2 1 O A ARG 124 ? ? NE2 A GLN 127 ? ? 2.13 3 1 NH2 A ARG 196 ? ? OD1 B ASP 37 ? ? 2.19 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 C A GLU 356 ? ? N A PRO 357 ? ? CA A PRO 357 ? ? 128.34 119.30 9.04 1.50 Y 2 1 CG1 A VAL 358 ? ? CB A VAL 358 ? ? CG2 A VAL 358 ? ? 96.46 110.90 -14.44 1.60 N 3 1 C A GLU 413 ? ? N A PRO 414 ? ? CA A PRO 414 ? ? 109.24 119.30 -10.06 1.50 Y 4 1 C A GLU 447 ? ? N A PRO 448 ? ? CA A PRO 448 ? ? 129.39 119.30 10.09 1.50 Y 5 1 N A THR 518 ? ? CA A THR 518 ? ? C A THR 518 ? ? 127.53 111.00 16.53 2.70 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 39 ? ? -47.20 151.60 2 1 LYS A 67 ? ? 49.45 71.92 3 1 LYS A 70 ? ? -41.50 80.90 4 1 ASN A 73 ? ? -174.26 135.19 5 1 SER A 85 ? ? -66.71 -118.25 6 1 GLU A 100 ? ? -54.46 98.87 7 1 ASN A 110 ? ? -72.68 24.81 8 1 ASP A 126 ? ? -54.32 -2.88 9 1 GLN A 127 ? ? -157.97 38.35 10 1 PHE A 170 ? ? 84.48 -19.59 11 1 ASP A 174 ? ? 55.79 110.77 12 1 ASN A 178 ? ? 38.52 1.33 13 1 LEU A 278 ? ? -92.43 55.35 14 1 ALA A 280 ? ? -103.49 -65.35 15 1 ASN A 299 ? ? -100.27 -74.88 16 1 ASP A 300 ? ? -116.35 67.81 17 1 ARG A 302 ? ? -108.76 -78.57 18 1 SER A 313 ? ? -103.41 -163.07 19 1 ALA A 320 ? ? -175.05 128.92 20 1 THR A 335 ? ? 71.40 41.01 21 1 PRO A 336 ? ? -66.29 85.90 22 1 ASN A 404 ? ? -124.12 -168.62 23 1 ASN A 405 ? ? -63.32 2.98 24 1 LEU A 436 ? ? -104.97 -89.62 25 1 TYR A 461 ? ? -104.07 76.58 26 1 PRO A 466 ? ? -76.08 41.82 27 1 MET A 474 ? ? 150.58 154.94 28 1 GLN A 482 ? ? 47.03 1.90 29 1 ASP A 513 ? ? 169.76 11.35 30 1 VAL A 516 ? ? -29.50 142.05 31 1 GLN A 519 ? ? -124.14 -123.26 32 1 GLN A 525 ? ? -37.84 144.88 33 1 PRO A 546 ? ? -69.42 -177.53 34 1 SER A 548 ? ? -46.66 108.85 35 1 ASP A 560 ? ? -58.01 103.14 36 1 GLN A 563 ? ? -91.71 32.59 37 1 ASN A 585 ? ? 37.44 51.92 38 1 SER A 593 ? ? -162.19 108.04 39 1 SER B 35 ? ? 57.70 -166.58 40 1 VAL B 45 ? ? -50.58 101.79 41 1 TYR B 57 ? ? -101.82 54.66 42 1 TYR B 59 ? ? -61.83 -71.29 43 1 PRO B 88 ? ? -69.84 62.02 44 1 ILE B 89 ? ? 20.46 106.45 45 1 ASP B 92 ? ? -88.92 -152.15 46 1 SER B 94 ? ? -90.04 -78.57 47 1 ARG B 95 ? ? -72.46 -78.58 48 1 ASN B 122 ? ? -79.07 -109.85 49 1 SER B 123 ? ? -155.66 0.07 50 1 THR B 140 ? ? -37.69 100.91 51 1 TYR B 150 ? ? -63.26 -174.23 52 1 GLU B 168 ? ? -12.19 -33.13 53 1 LYS B 197 ? ? -107.50 -131.12 54 1 ARG B 198 ? ? -77.54 -103.28 55 1 TYR B 220 ? ? 179.54 146.42 56 1 PRO B 242 ? ? -57.89 179.14 57 1 LEU B 245 ? ? -121.09 -81.96 58 1 LYS B 251 ? ? -54.00 102.89 59 1 LEU B 252 ? ? -68.22 97.60 60 1 ASP B 294 ? ? -46.04 -90.40 61 1 GLU B 295 ? ? 72.09 42.45 62 1 ARG B 297 ? ? -143.67 -36.71 63 1 SER B 301 ? ? -72.13 -167.93 64 1 ILE B 303 ? ? -59.30 102.45 65 1 HIS B 309 ? ? -161.48 97.00 66 1 LEU B 310 ? ? 31.76 72.21 67 1 ASP B 322 ? ? -75.86 -77.73 68 1 GLU B 325 ? ? -85.20 -154.27 69 1 GLU B 337 ? ? -171.02 139.81 70 1 ASN B 338 ? ? -134.15 -153.32 71 1 LYS B 353 ? ? -74.51 -155.34 72 1 HIS B 356 ? ? -55.40 71.08 # _pdbx_validate_peptide_omega.id 1 _pdbx_validate_peptide_omega.PDB_model_num 1 _pdbx_validate_peptide_omega.auth_comp_id_1 PRO _pdbx_validate_peptide_omega.auth_asym_id_1 B _pdbx_validate_peptide_omega.auth_seq_id_1 88 _pdbx_validate_peptide_omega.PDB_ins_code_1 ? _pdbx_validate_peptide_omega.label_alt_id_1 ? _pdbx_validate_peptide_omega.auth_comp_id_2 ILE _pdbx_validate_peptide_omega.auth_asym_id_2 B _pdbx_validate_peptide_omega.auth_seq_id_2 89 _pdbx_validate_peptide_omega.PDB_ins_code_2 ? _pdbx_validate_peptide_omega.label_alt_id_2 ? _pdbx_validate_peptide_omega.omega 148.87 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 B LYS 353 ? CG ? B LYS 342 CG 2 1 Y 1 B LYS 353 ? CD ? B LYS 342 CD 3 1 Y 1 B LYS 353 ? CE ? B LYS 342 CE 4 1 Y 1 B LYS 353 ? NZ ? B LYS 342 NZ 5 1 Y 1 B HIS 354 ? CG ? B HIS 343 CG 6 1 Y 1 B HIS 354 ? ND1 ? B HIS 343 ND1 7 1 Y 1 B HIS 354 ? CD2 ? B HIS 343 CD2 8 1 Y 1 B HIS 354 ? CE1 ? B HIS 343 CE1 9 1 Y 1 B HIS 354 ? NE2 ? B HIS 343 NE2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLN 613 ? A GLN 586 2 1 Y 1 A SER 614 ? A SER 587 3 1 Y 1 A MET 615 ? A MET 588 4 1 Y 1 A PHE 616 ? A PHE 589 5 1 Y 1 A ALA 617 ? A ALA 590 6 1 Y 1 A LYS 618 ? A LYS 591 7 1 Y 1 A ASN 619 ? A ASN 592 8 1 Y 1 A PHE 620 ? A PHE 593 9 1 Y 1 A HIS 621 ? A HIS 594 10 1 Y 1 A VAL 622 ? A VAL 595 11 1 Y 1 A LYS 623 ? A LYS 596 12 1 Y 1 A ALA 624 ? A ALA 597 13 1 Y 1 A VAL 625 ? A VAL 598 14 1 Y 1 A MET 626 ? A MET 599 15 1 Y 1 A LYS 627 ? A LYS 600 16 1 Y 1 A THR 628 ? A THR 601 17 1 Y 1 A SER 629 ? A SER 602 18 1 Y 1 A VAL 630 ? A VAL 603 19 1 Y 1 A LEU 631 ? A LEU 604 20 1 Y 1 A LEU 632 ? A LEU 605 21 1 Y 1 A SER 633 ? A SER 606 22 1 Y 1 A TRP 634 ? A TRP 607 23 1 Y 1 A GLU 635 ? A GLU 608 24 1 Y 1 A ILE 636 ? A ILE 609 25 1 Y 1 A PRO 637 ? A PRO 610 26 1 Y 1 A GLU 638 ? A GLU 611 27 1 Y 1 A ASN 639 ? A ASN 612 28 1 Y 1 A TYR 640 ? A TYR 613 29 1 Y 1 A ASN 641 ? A ASN 614 30 1 Y 1 A SER 642 ? A SER 615 31 1 Y 1 A ALA 643 ? A ALA 616 32 1 Y 1 A MET 644 ? A MET 617 33 1 Y 1 A PRO 645 ? A PRO 618 34 1 Y 1 A PHE 646 ? A PHE 619 35 1 Y 1 A LYS 647 ? A LYS 620 36 1 Y 1 A ILE 648 ? A ILE 621 37 1 Y 1 A LEU 649 ? A LEU 622 38 1 Y 1 A TYR 650 ? A TYR 623 39 1 Y 1 A ASP 651 ? A ASP 624 40 1 Y 1 A ASP 652 ? A ASP 625 41 1 Y 1 A GLY 653 ? A GLY 626 42 1 Y 1 A LYS 654 ? A LYS 627 43 1 Y 1 A MET 655 ? A MET 628 44 1 Y 1 A VAL 656 ? A VAL 629 45 1 Y 1 A GLU 657 ? A GLU 630 46 1 Y 1 A GLU 658 ? A GLU 631 47 1 Y 1 A VAL 659 ? A VAL 632 48 1 Y 1 A ASP 660 ? A ASP 633 49 1 Y 1 A GLY 661 ? A GLY 634 50 1 Y 1 A ARG 662 ? A ARG 635 51 1 Y 1 A ALA 663 ? A ALA 636 52 1 Y 1 A THR 664 ? A THR 637 53 1 Y 1 A GLN 665 ? A GLN 638 54 1 Y 1 A LYS 666 ? A LYS 639 55 1 Y 1 A LEU 667 ? A LEU 640 56 1 Y 1 A ILE 668 ? A ILE 641 57 1 Y 1 A VAL 669 ? A VAL 642 58 1 Y 1 A ASN 670 ? A ASN 643 59 1 Y 1 A LEU 671 ? A LEU 644 60 1 Y 1 A LYS 672 ? A LYS 645 61 1 Y 1 A PRO 673 ? A PRO 646 62 1 Y 1 A GLU 674 ? A GLU 647 63 1 Y 1 A LYS 675 ? A LYS 648 64 1 Y 1 A SER 676 ? A SER 649 65 1 Y 1 A TYR 677 ? A TYR 650 66 1 Y 1 A SER 678 ? A SER 651 67 1 Y 1 A PHE 679 ? A PHE 652 68 1 Y 1 A VAL 680 ? A VAL 653 69 1 Y 1 A LEU 681 ? A LEU 654 70 1 Y 1 A THR 682 ? A THR 655 71 1 Y 1 A ASN 683 ? A ASN 656 72 1 Y 1 A ARG 684 ? A ARG 657 73 1 Y 1 A GLY 685 ? A GLY 658 74 1 Y 1 A ASN 686 ? A ASN 659 75 1 Y 1 A SER 687 ? A SER 660 76 1 Y 1 A ALA 688 ? A ALA 661 77 1 Y 1 A GLY 689 ? A GLY 662 78 1 Y 1 A GLY 690 ? A GLY 663 79 1 Y 1 A LEU 691 ? A LEU 664 80 1 Y 1 A GLN 692 ? A GLN 665 81 1 Y 1 A HIS 693 ? A HIS 666 82 1 Y 1 A ARG 694 ? A ARG 667 83 1 Y 1 A VAL 695 ? A VAL 668 84 1 Y 1 A THR 696 ? A THR 669 85 1 Y 1 A ALA 697 ? A ALA 670 86 1 Y 1 A LYS 698 ? A LYS 671 87 1 Y 1 A THR 699 ? A THR 672 88 1 Y 1 A ALA 700 ? A ALA 673 89 1 Y 1 A PRO 701 ? A PRO 674 90 1 Y 1 A ASP 702 ? A ASP 675 91 1 Y 1 A VAL 703 ? A VAL 676 92 1 Y 1 A LEU 704 ? A LEU 677 93 1 Y 1 A ARG 705 ? A ARG 678 94 1 Y 1 A THR 706 ? A THR 679 95 1 Y 1 A LYS 707 ? A LYS 680 96 1 Y 1 A PRO 708 ? A PRO 681 97 1 Y 1 A ALA 709 ? A ALA 682 98 1 Y 1 A PHE 710 ? A PHE 683 99 1 Y 1 A ILE 711 ? A ILE 684 100 1 Y 1 A GLY 712 ? A GLY 685 101 1 Y 1 A LYS 713 ? A LYS 686 102 1 Y 1 A THR 714 ? A THR 687 103 1 Y 1 A ASN 715 ? A ASN 688 104 1 Y 1 A LEU 716 ? A LEU 689 105 1 Y 1 A ASP 717 ? A ASP 690 106 1 Y 1 A GLY 718 ? A GLY 691 107 1 Y 1 A MET 719 ? A MET 692 108 1 Y 1 A ILE 720 ? A ILE 693 109 1 Y 1 A THR 721 ? A THR 694 110 1 Y 1 A VAL 722 ? A VAL 695 111 1 Y 1 A GLN 723 ? A GLN 696 112 1 Y 1 A LEU 724 ? A LEU 697 113 1 Y 1 A PRO 725 ? A PRO 698 114 1 Y 1 A ASP 726 ? A ASP 699 115 1 Y 1 A VAL 727 ? A VAL 700 116 1 Y 1 A PRO 728 ? A PRO 701 117 1 Y 1 A ALA 729 ? A ALA 702 118 1 Y 1 A ASN 730 ? A ASN 703 119 1 Y 1 A GLU 731 ? A GLU 704 120 1 Y 1 A ASN 732 ? A ASN 705 121 1 Y 1 A ILE 733 ? A ILE 706 122 1 Y 1 A LYS 734 ? A LYS 707 123 1 Y 1 A GLY 735 ? A GLY 708 124 1 Y 1 A TYR 736 ? A TYR 709 125 1 Y 1 A TYR 737 ? A TYR 710 126 1 Y 1 A ILE 738 ? A ILE 711 127 1 Y 1 A ILE 739 ? A ILE 712 128 1 Y 1 A ILE 740 ? A ILE 713 129 1 Y 1 A VAL 741 ? A VAL 714 130 1 Y 1 A PRO 742 ? A PRO 715 131 1 Y 1 A LEU 743 ? A LEU 716 132 1 Y 1 A LYS 744 ? A LYS 717 133 1 Y 1 A LYS 745 ? A LYS 718 134 1 Y 1 A SER 746 ? A SER 719 135 1 Y 1 A ARG 747 ? A ARG 720 136 1 Y 1 A GLY 748 ? A GLY 721 137 1 Y 1 A LYS 749 ? A LYS 722 138 1 Y 1 A PHE 750 ? A PHE 723 139 1 Y 1 A ILE 751 ? A ILE 724 140 1 Y 1 A LYS 752 ? A LYS 725 141 1 Y 1 A PRO 753 ? A PRO 726 142 1 Y 1 A TRP 754 ? A TRP 727 143 1 Y 1 A GLU 755 ? A GLU 728 144 1 Y 1 A SER 756 ? A SER 729 145 1 Y 1 A PRO 757 ? A PRO 730 146 1 Y 1 A ASP 758 ? A ASP 731 147 1 Y 1 A GLU 759 ? A GLU 732 148 1 Y 1 A MET 760 ? A MET 733 149 1 Y 1 A GLU 761 ? A GLU 734 150 1 Y 1 A LEU 762 ? A LEU 735 151 1 Y 1 A ASP 763 ? A ASP 736 152 1 Y 1 A GLU 764 ? A GLU 737 153 1 Y 1 A LEU 765 ? A LEU 738 154 1 Y 1 A LEU 766 ? A LEU 739 155 1 Y 1 A LYS 767 ? A LYS 740 156 1 Y 1 A GLU 768 ? A GLU 741 157 1 Y 1 A ILE 769 ? A ILE 742 158 1 Y 1 A SER 770 ? A SER 743 159 1 Y 1 A ARG 771 ? A ARG 744 160 1 Y 1 A LYS 772 ? A LYS 745 161 1 Y 1 A ARG 773 ? A ARG 746 162 1 Y 1 A ARG 774 ? A ARG 747 163 1 Y 1 A SER 775 ? A SER 748 164 1 Y 1 A ILE 776 ? A ILE 749 165 1 Y 1 A ARG 777 ? A ARG 750 166 1 Y 1 A TYR 778 ? A TYR 751 167 1 Y 1 A GLY 779 ? A GLY 752 168 1 Y 1 A ARG 780 ? A ARG 753 169 1 Y 1 A GLU 781 ? A GLU 754 170 1 Y 1 A VAL 782 ? A VAL 755 171 1 Y 1 A GLU 783 ? A GLU 756 172 1 Y 1 A LEU 784 ? A LEU 757 173 1 Y 1 A LYS 785 ? A LYS 758 174 1 Y 1 A PRO 786 ? A PRO 759 175 1 Y 1 A TYR 787 ? A TYR 760 176 1 Y 1 A ILE 788 ? A ILE 761 177 1 Y 1 A ALA 789 ? A ALA 762 178 1 Y 1 A ALA 790 ? A ALA 763 179 1 Y 1 A HIS 791 ? A HIS 764 180 1 Y 1 A PHE 792 ? A PHE 765 181 1 Y 1 A ASP 793 ? A ASP 766 182 1 Y 1 A VAL 794 ? A VAL 767 183 1 Y 1 A LEU 795 ? A LEU 768 184 1 Y 1 A PRO 796 ? A PRO 769 185 1 Y 1 A THR 797 ? A THR 770 186 1 Y 1 A GLU 798 ? A GLU 771 187 1 Y 1 A PHE 799 ? A PHE 772 188 1 Y 1 A THR 800 ? A THR 773 189 1 Y 1 A LEU 801 ? A LEU 774 190 1 Y 1 A GLY 802 ? A GLY 775 191 1 Y 1 A ASP 803 ? A ASP 776 192 1 Y 1 A ASP 804 ? A ASP 777 193 1 Y 1 A LYS 805 ? A LYS 778 194 1 Y 1 A HIS 806 ? A HIS 779 195 1 Y 1 A TYR 807 ? A TYR 780 196 1 Y 1 A GLY 808 ? A GLY 781 197 1 Y 1 A GLY 809 ? A GLY 782 198 1 Y 1 A PHE 810 ? A PHE 783 199 1 Y 1 A THR 811 ? A THR 784 200 1 Y 1 A ASN 812 ? A ASN 785 201 1 Y 1 A LYS 813 ? A LYS 786 202 1 Y 1 A GLN 814 ? A GLN 787 203 1 Y 1 A LEU 815 ? A LEU 788 204 1 Y 1 A GLN 816 ? A GLN 789 205 1 Y 1 A SER 817 ? A SER 790 206 1 Y 1 A GLY 818 ? A GLY 791 207 1 Y 1 A GLN 819 ? A GLN 792 208 1 Y 1 A GLU 820 ? A GLU 793 209 1 Y 1 A TYR 821 ? A TYR 794 210 1 Y 1 A VAL 822 ? A VAL 795 211 1 Y 1 A PHE 823 ? A PHE 796 212 1 Y 1 A PHE 824 ? A PHE 797 213 1 Y 1 A VAL 825 ? A VAL 798 214 1 Y 1 A LEU 826 ? A LEU 799 215 1 Y 1 A ALA 827 ? A ALA 800 216 1 Y 1 A VAL 828 ? A VAL 801 217 1 Y 1 A MET 829 ? A MET 802 218 1 Y 1 A ASP 830 ? A ASP 803 219 1 Y 1 A HIS 831 ? A HIS 804 220 1 Y 1 A ALA 832 ? A ALA 805 221 1 Y 1 A GLU 833 ? A GLU 806 222 1 Y 1 A SER 834 ? A SER 807 223 1 Y 1 A LYS 835 ? A LYS 808 224 1 Y 1 A MET 836 ? A MET 809 225 1 Y 1 A TYR 837 ? A TYR 810 226 1 Y 1 A ALA 838 ? A ALA 811 227 1 Y 1 A THR 839 ? A THR 812 228 1 Y 1 A SER 840 ? A SER 813 229 1 Y 1 A PRO 841 ? A PRO 814 230 1 Y 1 A TYR 842 ? A TYR 815 231 1 Y 1 A SER 843 ? A SER 816 232 1 Y 1 A ASP 844 ? A ASP 817 233 1 Y 1 A PRO 845 ? A PRO 818 234 1 Y 1 A VAL 846 ? A VAL 819 235 1 Y 1 A VAL 847 ? A VAL 820 236 1 Y 1 A SER 848 ? A SER 821 237 1 Y 1 A MET 849 ? A MET 822 238 1 Y 1 A ASP 850 ? A ASP 823 239 1 Y 1 A LEU 851 ? A LEU 824 240 1 Y 1 A ASP 852 ? A ASP 825 241 1 Y 1 A PRO 853 ? A PRO 826 242 1 Y 1 A GLN 854 ? A GLN 827 243 1 Y 1 A PRO 855 ? A PRO 828 244 1 Y 1 A ILE 856 ? A ILE 829 245 1 Y 1 A THR 857 ? A THR 830 246 1 Y 1 A ASP 858 ? A ASP 831 247 1 Y 1 A GLU 859 ? A GLU 832 248 1 Y 1 A GLU 860 ? A GLU 833 249 1 Y 1 A GLU 861 ? A GLU 834 250 1 Y 1 A LYS 862 ? A LYS 835 251 1 Y 1 A HIS 863 ? A HIS 836 252 1 Y 1 A HIS 864 ? A HIS 837 253 1 Y 1 A HIS 865 ? A HIS 838 254 1 Y 1 A HIS 866 ? A HIS 839 255 1 Y 1 A HIS 867 ? A HIS 840 256 1 Y 1 A HIS 868 ? A HIS 841 257 1 Y 1 B ALA 12 ? B ALA 1 258 1 Y 1 B GLN 13 ? B GLN 2 259 1 Y 1 B PRO 14 ? B PRO 3 260 1 Y 1 B ALA 15 ? B ALA 4 261 1 Y 1 B ALA 16 ? B ALA 5 262 1 Y 1 B ARG 17 ? B ARG 6 263 1 Y 1 B ASP 18 ? B ASP 7 264 1 Y 1 B LEU 19 ? B LEU 8 265 1 Y 1 B LYS 20 ? B LYS 9 266 1 Y 1 B VAL 21 ? B VAL 10 267 1 Y 1 B VAL 22 ? B VAL 11 268 1 Y 1 B THR 23 ? B THR 12 269 1 Y 1 B LYS 24 ? B LYS 13 270 1 Y 1 B ARG 25 ? B ARG 14 271 1 Y 1 B GLY 26 ? B GLY 15 272 1 Y 1 B SER 27 ? B SER 16 273 1 Y 1 B ALA 28 ? B ALA 17 274 1 Y 1 B ASP 29 ? B ASP 18 275 1 Y 1 B GLY 30 ? B GLY 19 276 1 Y 1 B LEU 172 ? B LEU 161 277 1 Y 1 B PRO 173 ? B PRO 162 278 1 Y 1 B THR 174 ? B THR 163 279 1 Y 1 B ARG 175 ? B ARG 164 280 1 Y 1 B HIS 359 ? B HIS 348 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 3 N-ACETYL-D-GLUCOSAMINE NAG 4 BETA-D-MANNOSE BMA 5 ALPHA-D-MANNOSE MAN #