data_4XP9 # _entry.id 4XP9 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4XP9 WWPDB D_1000206063 # loop_ _pdbx_database_related.db_name _pdbx_database_related.details _pdbx_database_related.db_id _pdbx_database_related.content_type PDB . 4XNX unspecified PDB . 4XP1 unspecified PDB . 4XP4 unspecified PDB . 4XP5 unspecified PDB . 4XP6 unspecified PDB . 4XPA unspecified PDB . 4XPB unspecified PDB . 4XPF unspecified PDB . 4XPG unspecified PDB . 4XPH unspecified PDB . 4XPT unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 4XP9 _pdbx_database_status.recvd_initial_deposition_date 2015-01-16 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Aravind, P.' 1 'Wang, K.' 2 'Gouaux, E.' 3 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country UK _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev Nature _citation.journal_id_ASTM NATUAS _citation.journal_id_CSD 0006 _citation.journal_id_ISSN 1476-4687 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 521 _citation.language ? _citation.page_first 322 _citation.page_last 327 _citation.title 'Neurotransmitter and psychostimulant recognition by the dopamine transporter.' _citation.year 2015 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1038/nature14431 _citation.pdbx_database_id_PubMed 25970245 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Wang, K.H.' 1 primary 'Penmatsa, A.' 2 primary 'Gouaux, E.' 3 # _cell.entry_id 4XP9 _cell.length_a 97.348 _cell.length_b 140.748 _cell.length_c 166.760 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? # _symmetry.entry_id 4XP9 _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man Transporter 60728.301 1 ? 'V74A, L415A' ? ? 2 polymer man 'ANTIBODY FRAGMENT HEAVY CHAIN-PROTEIN, 9D5-HEAVY CHAIN' 23191.498 1 ? ? ? ? 3 polymer man 'ANTIBODY FRAGMENT LIGHT CHAIN-PROTEIN, 9D5-LIGHT CHAIN' 23619.430 1 ? ? ? ? 4 non-polymer man 'CHOLESTEROL HEMISUCCINATE' 486.726 1 ? ? ? ? 5 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 6 non-polymer man MALTOSE 342.296 1 ? ? ? ? 7 non-polymer syn '3[N-MORPHOLINO]PROPANE SULFONIC ACID' 209.263 1 ? ? ? ? 8 non-polymer syn CHOLESTEROL 386.654 1 ? ? ? ? 9 non-polymer syn '(2S)-1-phenylpropan-2-amine' 135.206 1 ? ? ? ? 10 non-polymer syn '1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE' 162.227 2 ? ? ? ? 11 non-polymer syn 'SODIUM ION' 22.990 2 ? ? ? ? 12 non-polymer syn 'CHLORIDE ION' 35.453 1 ? ? ? ? 13 water nat water 18.015 33 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLAVGGIPLFYMELALGQHNRKGAITCWGRLVP LFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFEGHVEGFQSAASEYFNRYILELNR SEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIY KAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEG PGLVFVVYPAAIATMPASTFWALIFFMMLATLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQ GGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPL TYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRDQQLLVPR ; ;DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLAVGGIPLFYMELALGQHNRKGAITCWGRLVP LFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFEGHVEGFQSAASEYFNRYILELNR SEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIY KAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEG PGLVFVVYPAAIATMPASTFWALIFFMMLATLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQ GGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPL TYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRDQQLLVPR ; C ? 2 'polypeptide(L)' no no ;ENVLTQSPAIMSTSPGEKVTMTCRASSSVGSSYLHWYQQKSGASPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISSVE AEDAATYYCQQFSGYPLTFGSGTKLEMKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIEGSERQNGV LNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN ; ;ENVLTQSPAIMSTSPGEKVTMTCRASSSVGSSYLHWYQQKSGASPKLWIYSTSNLASGVPARFSGSGSGTSYSLTISSVE AEDAATYYCQQFSGYPLTFGSGTKLEMKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIEGSERQNGV LNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN ; L ? 3 'polypeptide(L)' no no ;EVQLVESGGGLVKPGGSLKLSCAASGFTFSSYAMSWVRQSPEKRLEWVAEISSGGRYIYYSDTVTGRFTISRDNARNILH LEMSSLRSEDTAMYYCARGEVRQRGFDYWGQGTTLTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTW NSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPR ; ;EVQLVESGGGLVKPGGSLKLSCAASGFTFSSYAMSWVRQSPEKRLEWVAEISSGGRYIYYSDTVTGRFTISRDNARNILH LEMSSLRSEDTAMYYCARGEVRQRGFDYWGQGTTLTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTW NSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPR ; H ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ASP n 1 2 GLU n 1 3 ARG n 1 4 GLU n 1 5 THR n 1 6 TRP n 1 7 SER n 1 8 GLY n 1 9 LYS n 1 10 VAL n 1 11 ASP n 1 12 PHE n 1 13 LEU n 1 14 LEU n 1 15 SER n 1 16 VAL n 1 17 ILE n 1 18 GLY n 1 19 PHE n 1 20 ALA n 1 21 VAL n 1 22 ASP n 1 23 LEU n 1 24 ALA n 1 25 ASN n 1 26 VAL n 1 27 TRP n 1 28 ARG n 1 29 PHE n 1 30 PRO n 1 31 TYR n 1 32 LEU n 1 33 CYS n 1 34 TYR n 1 35 LYS n 1 36 ASN n 1 37 GLY n 1 38 GLY n 1 39 GLY n 1 40 ALA n 1 41 PHE n 1 42 LEU n 1 43 VAL n 1 44 PRO n 1 45 TYR n 1 46 GLY n 1 47 ILE n 1 48 MET n 1 49 LEU n 1 50 ALA n 1 51 VAL n 1 52 GLY n 1 53 GLY n 1 54 ILE n 1 55 PRO n 1 56 LEU n 1 57 PHE n 1 58 TYR n 1 59 MET n 1 60 GLU n 1 61 LEU n 1 62 ALA n 1 63 LEU n 1 64 GLY n 1 65 GLN n 1 66 HIS n 1 67 ASN n 1 68 ARG n 1 69 LYS n 1 70 GLY n 1 71 ALA n 1 72 ILE n 1 73 THR n 1 74 CYS n 1 75 TRP n 1 76 GLY n 1 77 ARG n 1 78 LEU n 1 79 VAL n 1 80 PRO n 1 81 LEU n 1 82 PHE n 1 83 LYS n 1 84 GLY n 1 85 ILE n 1 86 GLY n 1 87 TYR n 1 88 ALA n 1 89 VAL n 1 90 VAL n 1 91 LEU n 1 92 ILE n 1 93 ALA n 1 94 PHE n 1 95 TYR n 1 96 VAL n 1 97 ASP n 1 98 PHE n 1 99 TYR n 1 100 TYR n 1 101 ASN n 1 102 VAL n 1 103 ILE n 1 104 ILE n 1 105 ALA n 1 106 TRP n 1 107 SER n 1 108 LEU n 1 109 ARG n 1 110 PHE n 1 111 PHE n 1 112 PHE n 1 113 ALA n 1 114 SER n 1 115 PHE n 1 116 THR n 1 117 ASN n 1 118 SER n 1 119 LEU n 1 120 PRO n 1 121 TRP n 1 122 THR n 1 123 SER n 1 124 CYS n 1 125 ASN n 1 126 ASN n 1 127 ILE n 1 128 TRP n 1 129 ASN n 1 130 THR n 1 131 PRO n 1 132 ASN n 1 133 CYS n 1 134 ARG n 1 135 PRO n 1 136 PHE n 1 137 GLU n 1 138 GLY n 1 139 HIS n 1 140 VAL n 1 141 GLU n 1 142 GLY n 1 143 PHE n 1 144 GLN n 1 145 SER n 1 146 ALA n 1 147 ALA n 1 148 SER n 1 149 GLU n 1 150 TYR n 1 151 PHE n 1 152 ASN n 1 153 ARG n 1 154 TYR n 1 155 ILE n 1 156 LEU n 1 157 GLU n 1 158 LEU n 1 159 ASN n 1 160 ARG n 1 161 SER n 1 162 GLU n 1 163 GLY n 1 164 ILE n 1 165 HIS n 1 166 ASP n 1 167 LEU n 1 168 GLY n 1 169 ALA n 1 170 ILE n 1 171 LYS n 1 172 TRP n 1 173 ASP n 1 174 MET n 1 175 ALA n 1 176 LEU n 1 177 CYS n 1 178 LEU n 1 179 LEU n 1 180 ILE n 1 181 VAL n 1 182 TYR n 1 183 LEU n 1 184 ILE n 1 185 CYS n 1 186 TYR n 1 187 PHE n 1 188 SER n 1 189 LEU n 1 190 TRP n 1 191 LYS n 1 192 GLY n 1 193 ILE n 1 194 SER n 1 195 THR n 1 196 SER n 1 197 GLY n 1 198 LYS n 1 199 VAL n 1 200 VAL n 1 201 TRP n 1 202 PHE n 1 203 THR n 1 204 ALA n 1 205 LEU n 1 206 PHE n 1 207 PRO n 1 208 TYR n 1 209 ALA n 1 210 VAL n 1 211 LEU n 1 212 LEU n 1 213 ILE n 1 214 LEU n 1 215 LEU n 1 216 ILE n 1 217 ARG n 1 218 GLY n 1 219 LEU n 1 220 THR n 1 221 LEU n 1 222 PRO n 1 223 GLY n 1 224 SER n 1 225 PHE n 1 226 LEU n 1 227 GLY n 1 228 ILE n 1 229 GLN n 1 230 TYR n 1 231 TYR n 1 232 LEU n 1 233 THR n 1 234 PRO n 1 235 ASN n 1 236 PHE n 1 237 SER n 1 238 ALA n 1 239 ILE n 1 240 TYR n 1 241 LYS n 1 242 ALA n 1 243 GLU n 1 244 VAL n 1 245 TRP n 1 246 VAL n 1 247 ASP n 1 248 ALA n 1 249 ALA n 1 250 THR n 1 251 GLN n 1 252 VAL n 1 253 PHE n 1 254 PHE n 1 255 SER n 1 256 LEU n 1 257 GLY n 1 258 PRO n 1 259 GLY n 1 260 PHE n 1 261 GLY n 1 262 VAL n 1 263 LEU n 1 264 LEU n 1 265 ALA n 1 266 TYR n 1 267 ALA n 1 268 SER n 1 269 TYR n 1 270 ASN n 1 271 LYS n 1 272 TYR n 1 273 HIS n 1 274 ASN n 1 275 ASN n 1 276 VAL n 1 277 TYR n 1 278 LYS n 1 279 ASP n 1 280 ALA n 1 281 LEU n 1 282 LEU n 1 283 THR n 1 284 SER n 1 285 PHE n 1 286 ILE n 1 287 ASN n 1 288 SER n 1 289 ALA n 1 290 THR n 1 291 SER n 1 292 PHE n 1 293 ILE n 1 294 ALA n 1 295 GLY n 1 296 PHE n 1 297 VAL n 1 298 ILE n 1 299 PHE n 1 300 SER n 1 301 VAL n 1 302 LEU n 1 303 GLY n 1 304 TYR n 1 305 MET n 1 306 ALA n 1 307 HIS n 1 308 THR n 1 309 LEU n 1 310 GLY n 1 311 VAL n 1 312 ARG n 1 313 ILE n 1 314 GLU n 1 315 ASP n 1 316 VAL n 1 317 ALA n 1 318 THR n 1 319 GLU n 1 320 GLY n 1 321 PRO n 1 322 GLY n 1 323 LEU n 1 324 VAL n 1 325 PHE n 1 326 VAL n 1 327 VAL n 1 328 TYR n 1 329 PRO n 1 330 ALA n 1 331 ALA n 1 332 ILE n 1 333 ALA n 1 334 THR n 1 335 MET n 1 336 PRO n 1 337 ALA n 1 338 SER n 1 339 THR n 1 340 PHE n 1 341 TRP n 1 342 ALA n 1 343 LEU n 1 344 ILE n 1 345 PHE n 1 346 PHE n 1 347 MET n 1 348 MET n 1 349 LEU n 1 350 ALA n 1 351 THR n 1 352 LEU n 1 353 GLY n 1 354 LEU n 1 355 ASP n 1 356 SER n 1 357 SER n 1 358 PHE n 1 359 GLY n 1 360 GLY n 1 361 SER n 1 362 GLU n 1 363 ALA n 1 364 ILE n 1 365 ILE n 1 366 THR n 1 367 ALA n 1 368 LEU n 1 369 SER n 1 370 ASP n 1 371 GLU n 1 372 PHE n 1 373 PRO n 1 374 LYS n 1 375 ILE n 1 376 LYS n 1 377 ARG n 1 378 ASN n 1 379 ARG n 1 380 GLU n 1 381 LEU n 1 382 PHE n 1 383 VAL n 1 384 ALA n 1 385 GLY n 1 386 LEU n 1 387 PHE n 1 388 SER n 1 389 LEU n 1 390 TYR n 1 391 PHE n 1 392 VAL n 1 393 VAL n 1 394 GLY n 1 395 LEU n 1 396 ALA n 1 397 SER n 1 398 CYS n 1 399 THR n 1 400 GLN n 1 401 GLY n 1 402 GLY n 1 403 PHE n 1 404 TYR n 1 405 PHE n 1 406 PHE n 1 407 HIS n 1 408 LEU n 1 409 LEU n 1 410 ASP n 1 411 ARG n 1 412 TYR n 1 413 ALA n 1 414 ALA n 1 415 GLY n 1 416 TYR n 1 417 SER n 1 418 ILE n 1 419 LEU n 1 420 VAL n 1 421 ALA n 1 422 VAL n 1 423 PHE n 1 424 PHE n 1 425 GLU n 1 426 ALA n 1 427 ILE n 1 428 ALA n 1 429 VAL n 1 430 SER n 1 431 TRP n 1 432 ILE n 1 433 TYR n 1 434 GLY n 1 435 THR n 1 436 ASN n 1 437 ARG n 1 438 PHE n 1 439 SER n 1 440 GLU n 1 441 ASP n 1 442 ILE n 1 443 ARG n 1 444 ASP n 1 445 MET n 1 446 ILE n 1 447 GLY n 1 448 PHE n 1 449 PRO n 1 450 PRO n 1 451 GLY n 1 452 ARG n 1 453 TYR n 1 454 TRP n 1 455 GLN n 1 456 VAL n 1 457 CYS n 1 458 TRP n 1 459 ARG n 1 460 PHE n 1 461 VAL n 1 462 ALA n 1 463 PRO n 1 464 ILE n 1 465 PHE n 1 466 LEU n 1 467 LEU n 1 468 PHE n 1 469 ILE n 1 470 THR n 1 471 VAL n 1 472 TYR n 1 473 GLY n 1 474 LEU n 1 475 ILE n 1 476 GLY n 1 477 TYR n 1 478 GLU n 1 479 PRO n 1 480 LEU n 1 481 THR n 1 482 TYR n 1 483 ALA n 1 484 ASP n 1 485 TYR n 1 486 VAL n 1 487 TYR n 1 488 PRO n 1 489 SER n 1 490 TRP n 1 491 ALA n 1 492 ASN n 1 493 ALA n 1 494 LEU n 1 495 GLY n 1 496 TRP n 1 497 CYS n 1 498 ILE n 1 499 ALA n 1 500 GLY n 1 501 SER n 1 502 SER n 1 503 VAL n 1 504 VAL n 1 505 MET n 1 506 ILE n 1 507 PRO n 1 508 ALA n 1 509 VAL n 1 510 ALA n 1 511 ILE n 1 512 PHE n 1 513 LYS n 1 514 LEU n 1 515 LEU n 1 516 SER n 1 517 THR n 1 518 PRO n 1 519 GLY n 1 520 SER n 1 521 LEU n 1 522 ARG n 1 523 GLN n 1 524 ARG n 1 525 PHE n 1 526 THR n 1 527 ILE n 1 528 LEU n 1 529 THR n 1 530 THR n 1 531 PRO n 1 532 TRP n 1 533 ARG n 1 534 ASP n 1 535 GLN n 1 536 GLN n 1 537 LEU n 1 538 LEU n 1 539 VAL n 1 540 PRO n 1 541 ARG n 2 1 GLU n 2 2 ASN n 2 3 VAL n 2 4 LEU n 2 5 THR n 2 6 GLN n 2 7 SER n 2 8 PRO n 2 9 ALA n 2 10 ILE n 2 11 MET n 2 12 SER n 2 13 THR n 2 14 SER n 2 15 PRO n 2 16 GLY n 2 17 GLU n 2 18 LYS n 2 19 VAL n 2 20 THR n 2 21 MET n 2 22 THR n 2 23 CYS n 2 24 ARG n 2 25 ALA n 2 26 SER n 2 27 SER n 2 28 SER n 2 29 VAL n 2 30 GLY n 2 31 SER n 2 32 SER n 2 33 TYR n 2 34 LEU n 2 35 HIS n 2 36 TRP n 2 37 TYR n 2 38 GLN n 2 39 GLN n 2 40 LYS n 2 41 SER n 2 42 GLY n 2 43 ALA n 2 44 SER n 2 45 PRO n 2 46 LYS n 2 47 LEU n 2 48 TRP n 2 49 ILE n 2 50 TYR n 2 51 SER n 2 52 THR n 2 53 SER n 2 54 ASN n 2 55 LEU n 2 56 ALA n 2 57 SER n 2 58 GLY n 2 59 VAL n 2 60 PRO n 2 61 ALA n 2 62 ARG n 2 63 PHE n 2 64 SER n 2 65 GLY n 2 66 SER n 2 67 GLY n 2 68 SER n 2 69 GLY n 2 70 THR n 2 71 SER n 2 72 TYR n 2 73 SER n 2 74 LEU n 2 75 THR n 2 76 ILE n 2 77 SER n 2 78 SER n 2 79 VAL n 2 80 GLU n 2 81 ALA n 2 82 GLU n 2 83 ASP n 2 84 ALA n 2 85 ALA n 2 86 THR n 2 87 TYR n 2 88 TYR n 2 89 CYS n 2 90 GLN n 2 91 GLN n 2 92 PHE n 2 93 SER n 2 94 GLY n 2 95 TYR n 2 96 PRO n 2 97 LEU n 2 98 THR n 2 99 PHE n 2 100 GLY n 2 101 SER n 2 102 GLY n 2 103 THR n 2 104 LYS n 2 105 LEU n 2 106 GLU n 2 107 MET n 2 108 LYS n 2 109 ARG n 2 110 ALA n 2 111 ASP n 2 112 ALA n 2 113 ALA n 2 114 PRO n 2 115 THR n 2 116 VAL n 2 117 SER n 2 118 ILE n 2 119 PHE n 2 120 PRO n 2 121 PRO n 2 122 SER n 2 123 SER n 2 124 GLU n 2 125 GLN n 2 126 LEU n 2 127 THR n 2 128 SER n 2 129 GLY n 2 130 GLY n 2 131 ALA n 2 132 SER n 2 133 VAL n 2 134 VAL n 2 135 CYS n 2 136 PHE n 2 137 LEU n 2 138 ASN n 2 139 ASN n 2 140 PHE n 2 141 TYR n 2 142 PRO n 2 143 LYS n 2 144 ASP n 2 145 ILE n 2 146 ASN n 2 147 VAL n 2 148 LYS n 2 149 TRP n 2 150 LYS n 2 151 ILE n 2 152 GLU n 2 153 GLY n 2 154 SER n 2 155 GLU n 2 156 ARG n 2 157 GLN n 2 158 ASN n 2 159 GLY n 2 160 VAL n 2 161 LEU n 2 162 ASN n 2 163 SER n 2 164 TRP n 2 165 THR n 2 166 ASP n 2 167 GLN n 2 168 ASP n 2 169 SER n 2 170 LYS n 2 171 ASP n 2 172 SER n 2 173 THR n 2 174 TYR n 2 175 SER n 2 176 MET n 2 177 SER n 2 178 SER n 2 179 THR n 2 180 LEU n 2 181 THR n 2 182 LEU n 2 183 THR n 2 184 LYS n 2 185 ASP n 2 186 GLU n 2 187 TYR n 2 188 GLU n 2 189 ARG n 2 190 HIS n 2 191 ASN n 2 192 SER n 2 193 TYR n 2 194 THR n 2 195 CYS n 2 196 GLU n 2 197 ALA n 2 198 THR n 2 199 HIS n 2 200 LYS n 2 201 THR n 2 202 SER n 2 203 THR n 2 204 SER n 2 205 PRO n 2 206 ILE n 2 207 VAL n 2 208 LYS n 2 209 SER n 2 210 PHE n 2 211 ASN n 2 212 ARG n 2 213 ASN n 3 1 GLU n 3 2 VAL n 3 3 GLN n 3 4 LEU n 3 5 VAL n 3 6 GLU n 3 7 SER n 3 8 GLY n 3 9 GLY n 3 10 GLY n 3 11 LEU n 3 12 VAL n 3 13 LYS n 3 14 PRO n 3 15 GLY n 3 16 GLY n 3 17 SER n 3 18 LEU n 3 19 LYS n 3 20 LEU n 3 21 SER n 3 22 CYS n 3 23 ALA n 3 24 ALA n 3 25 SER n 3 26 GLY n 3 27 PHE n 3 28 THR n 3 29 PHE n 3 30 SER n 3 31 SER n 3 32 TYR n 3 33 ALA n 3 34 MET n 3 35 SER n 3 36 TRP n 3 37 VAL n 3 38 ARG n 3 39 GLN n 3 40 SER n 3 41 PRO n 3 42 GLU n 3 43 LYS n 3 44 ARG n 3 45 LEU n 3 46 GLU n 3 47 TRP n 3 48 VAL n 3 49 ALA n 3 50 GLU n 3 51 ILE n 3 52 SER n 3 53 SER n 3 54 GLY n 3 55 GLY n 3 56 ARG n 3 57 TYR n 3 58 ILE n 3 59 TYR n 3 60 TYR n 3 61 SER n 3 62 ASP n 3 63 THR n 3 64 VAL n 3 65 THR n 3 66 GLY n 3 67 ARG n 3 68 PHE n 3 69 THR n 3 70 ILE n 3 71 SER n 3 72 ARG n 3 73 ASP n 3 74 ASN n 3 75 ALA n 3 76 ARG n 3 77 ASN n 3 78 ILE n 3 79 LEU n 3 80 HIS n 3 81 LEU n 3 82 GLU n 3 83 MET n 3 84 SER n 3 85 SER n 3 86 LEU n 3 87 ARG n 3 88 SER n 3 89 GLU n 3 90 ASP n 3 91 THR n 3 92 ALA n 3 93 MET n 3 94 TYR n 3 95 TYR n 3 96 CYS n 3 97 ALA n 3 98 ARG n 3 99 GLY n 3 100 GLU n 3 101 VAL n 3 102 ARG n 3 103 GLN n 3 104 ARG n 3 105 GLY n 3 106 PHE n 3 107 ASP n 3 108 TYR n 3 109 TRP n 3 110 GLY n 3 111 GLN n 3 112 GLY n 3 113 THR n 3 114 THR n 3 115 LEU n 3 116 THR n 3 117 VAL n 3 118 SER n 3 119 SER n 3 120 ALA n 3 121 LYS n 3 122 THR n 3 123 THR n 3 124 ALA n 3 125 PRO n 3 126 SER n 3 127 VAL n 3 128 TYR n 3 129 PRO n 3 130 LEU n 3 131 ALA n 3 132 PRO n 3 133 VAL n 3 134 CYS n 3 135 GLY n 3 136 ASP n 3 137 THR n 3 138 THR n 3 139 GLY n 3 140 SER n 3 141 SER n 3 142 VAL n 3 143 THR n 3 144 LEU n 3 145 GLY n 3 146 CYS n 3 147 LEU n 3 148 VAL n 3 149 LYS n 3 150 GLY n 3 151 TYR n 3 152 PHE n 3 153 PRO n 3 154 GLU n 3 155 PRO n 3 156 VAL n 3 157 THR n 3 158 LEU n 3 159 THR n 3 160 TRP n 3 161 ASN n 3 162 SER n 3 163 GLY n 3 164 SER n 3 165 LEU n 3 166 SER n 3 167 SER n 3 168 GLY n 3 169 VAL n 3 170 HIS n 3 171 THR n 3 172 PHE n 3 173 PRO n 3 174 ALA n 3 175 VAL n 3 176 LEU n 3 177 GLN n 3 178 SER n 3 179 ASP n 3 180 LEU n 3 181 TYR n 3 182 THR n 3 183 LEU n 3 184 SER n 3 185 SER n 3 186 SER n 3 187 VAL n 3 188 THR n 3 189 VAL n 3 190 THR n 3 191 SER n 3 192 SER n 3 193 THR n 3 194 TRP n 3 195 PRO n 3 196 SER n 3 197 GLN n 3 198 SER n 3 199 ILE n 3 200 THR n 3 201 CYS n 3 202 ASN n 3 203 VAL n 3 204 ALA n 3 205 HIS n 3 206 PRO n 3 207 ALA n 3 208 SER n 3 209 SER n 3 210 THR n 3 211 LYS n 3 212 VAL n 3 213 ASP n 3 214 LYS n 3 215 LYS n 3 216 ILE n 3 217 GLU n 3 218 PRO n 3 219 ARG n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample 'Biological sequence' 1 541 'Fruit fly' ? 'DAT, CG8380, Dmel_CG8380' ? ? ? ? ? ? 'Drosophila melanogaster' 7227 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? GnTI-HEK293s ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample 'Biological sequence' 1 213 Mouse ? ? ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 3 1 sample 'Biological sequence' 1 219 Mouse ? ? ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin 1 UNP A0A0B4KEX2_DROME A0A0B4KEX2 ? 1 ;DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVP LFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQS LLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKV VWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKD ALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFG GSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFS EDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPG SLRQRFTILTTPWRDQQ ; 25 2 PDB 4XP9 4XP9 ? 2 ? 1 3 PDB 4XP9 4XP9 ? 3 ? 1 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4XP9 C 1 ? 536 ? A0A0B4KEX2 25 ? 601 ? 25 601 2 2 4XP9 L 1 ? 213 ? 4XP9 1 ? 213 ? 1 213 3 3 4XP9 H 1 ? 219 ? 4XP9 1 ? 219 ? 1 219 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 4XP9 ALA C 50 ? UNP A0A0B4KEX2 VAL 74 'engineered mutation' 74 1 1 4XP9 ? C ? ? UNP A0A0B4KEX2 SER 162 deletion ? 2 1 4XP9 ? C ? ? UNP A0A0B4KEX2 GLN 163 deletion ? 3 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ASN 164 deletion ? 4 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ALA 165 deletion ? 5 1 4XP9 ? C ? ? UNP A0A0B4KEX2 SER 166 deletion ? 6 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ARG 167 deletion ? 7 1 4XP9 ? C ? ? UNP A0A0B4KEX2 VAL 168 deletion ? 8 1 4XP9 ? C ? ? UNP A0A0B4KEX2 PRO 169 deletion ? 9 1 4XP9 ? C ? ? UNP A0A0B4KEX2 VAL 170 deletion ? 10 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ILE 171 deletion ? 11 1 4XP9 ? C ? ? UNP A0A0B4KEX2 GLY 172 deletion ? 12 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ASN 173 deletion ? 13 1 4XP9 ? C ? ? UNP A0A0B4KEX2 TYR 174 deletion ? 14 1 4XP9 ? C ? ? UNP A0A0B4KEX2 SER 175 deletion ? 15 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ASP 176 deletion ? 16 1 4XP9 ? C ? ? UNP A0A0B4KEX2 LEU 177 deletion ? 17 1 4XP9 ? C ? ? UNP A0A0B4KEX2 TYR 178 deletion ? 18 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ALA 179 deletion ? 19 1 4XP9 ? C ? ? UNP A0A0B4KEX2 MET 180 deletion ? 20 1 4XP9 ? C ? ? UNP A0A0B4KEX2 GLY 181 deletion ? 21 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ASN 182 deletion ? 22 1 4XP9 ? C ? ? UNP A0A0B4KEX2 GLN 183 deletion ? 23 1 4XP9 ? C ? ? UNP A0A0B4KEX2 SER 184 deletion ? 24 1 4XP9 ? C ? ? UNP A0A0B4KEX2 LEU 185 deletion ? 25 1 4XP9 ? C ? ? UNP A0A0B4KEX2 LEU 186 deletion ? 26 1 4XP9 ? C ? ? UNP A0A0B4KEX2 TYR 187 deletion ? 27 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ASN 188 deletion ? 28 1 4XP9 ? C ? ? UNP A0A0B4KEX2 GLU 189 deletion ? 29 1 4XP9 ? C ? ? UNP A0A0B4KEX2 THR 190 deletion ? 30 1 4XP9 ? C ? ? UNP A0A0B4KEX2 TYR 191 deletion ? 31 1 4XP9 ? C ? ? UNP A0A0B4KEX2 MET 192 deletion ? 32 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ASN 193 deletion ? 33 1 4XP9 ? C ? ? UNP A0A0B4KEX2 GLY 194 deletion ? 34 1 4XP9 ? C ? ? UNP A0A0B4KEX2 SER 195 deletion ? 35 1 4XP9 ? C ? ? UNP A0A0B4KEX2 SER 196 deletion ? 36 1 4XP9 ? C ? ? UNP A0A0B4KEX2 LEU 197 deletion ? 37 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ASP 198 deletion ? 38 1 4XP9 ? C ? ? UNP A0A0B4KEX2 THR 199 deletion ? 39 1 4XP9 ? C ? ? UNP A0A0B4KEX2 SER 200 deletion ? 40 1 4XP9 ? C ? ? UNP A0A0B4KEX2 ALA 201 deletion ? 41 1 4XP9 ? C ? ? UNP A0A0B4KEX2 VAL 202 deletion ? 42 1 4XP9 ALA C 350 ? UNP A0A0B4KEX2 LEU 415 'engineered mutation' 415 43 1 4XP9 LEU C 537 ? UNP A0A0B4KEX2 ? ? 'expression tag' 602 44 1 4XP9 LEU C 538 ? UNP A0A0B4KEX2 ? ? 'expression tag' 603 45 1 4XP9 VAL C 539 ? UNP A0A0B4KEX2 ? ? 'expression tag' 604 46 1 4XP9 PRO C 540 ? UNP A0A0B4KEX2 ? ? 'expression tag' 605 47 1 4XP9 ARG C 541 ? UNP A0A0B4KEX2 ? ? 'expression tag' 606 48 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight 1WE non-polymer . '(2S)-1-phenylpropan-2-amine' 'Dextroamphetamine, D-amphetamine, Dexamphetamine, Dexedrine, Dextrostat' 'C9 H13 N' 135.206 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CL non-polymer . 'CHLORIDE ION' ? 'Cl -1' 35.453 CLR non-polymer . CHOLESTEROL ? 'C27 H46 O' 386.654 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAL D-saccharide . MALTOSE ? 'C12 H22 O11' 342.296 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MPO non-polymer . '3[N-MORPHOLINO]PROPANE SULFONIC ACID' ? 'C7 H15 N O4 S' 209.263 NA non-polymer . 'SODIUM ION' ? 'Na 1' 22.990 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 P4G non-polymer . '1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE' ? 'C8 H18 O3' 162.227 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 Y01 non-polymer . 'CHOLESTEROL HEMISUCCINATE' ? 'C31 H50 O4' 486.726 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 4XP9 _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 5.33 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 76.94 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH 7.0 _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 277 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details 'PEG 600 (36%), MOPS (0.1M)' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'ADSC QUANTUM 315r' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2014-09-19 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator 'Double Crystal' _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.00 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'ALS BEAMLINE 8.2.1' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 1.00 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline 8.2.1 _diffrn_source.pdbx_synchrotron_site ALS # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 4XP9 _reflns.observed_criterion_sigma_I ? _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 50.000 _reflns.d_resolution_high 2.800 _reflns.number_obs 55464 _reflns.number_all ? _reflns.percent_possible_obs 96.6 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 18.1000 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 3.700 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 4XP9 _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 55464 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.040 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 46.72 _refine.ls_d_res_high 2.80 _refine.ls_percent_reflns_obs 96.8 _refine.ls_R_factor_obs 0.212 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.211 _refine.ls_R_factor_R_free 0.242 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 4.880 _refine.ls_number_reflns_R_free 5175 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean 85.19 _refine.aniso_B[1][1] ? _refine.aniso_B[2][2] ? _refine.aniso_B[3][3] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][3] ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_ls_cross_valid_method 'FREE R-VALUE' _refine.details ? _refine.pdbx_starting_model 4M48 _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.370 _refine.pdbx_overall_phase_error 26.970 _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 7484 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 148 _refine_hist.number_atoms_solvent 33 _refine_hist.number_atoms_total 7665 _refine_hist.d_res_high 2.80 _refine_hist.d_res_low 46.72 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function f_bond_d 0.007 ? ? 7859 'X-RAY DIFFRACTION' ? f_angle_d 1.168 ? ? 10723 'X-RAY DIFFRACTION' ? f_dihedral_angle_d 13.208 ? ? 2695 'X-RAY DIFFRACTION' ? f_chiral_restr 0.044 ? ? 1207 'X-RAY DIFFRACTION' ? f_plane_restr 0.006 ? ? 1321 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_all _refine_ls_shell.R_factor_all 'X-RAY DIFFRACTION' . 2.7952 2.8269 2112 0.4002 62.00 0.4374 . . 114 . . 'X-RAY DIFFRACTION' . 2.8269 2.8602 2938 0.3807 84.00 0.3508 . . 146 . . 'X-RAY DIFFRACTION' . 2.8602 2.8950 3262 0.3408 94.00 0.3791 . . 152 . . 'X-RAY DIFFRACTION' . 2.8950 2.9317 3179 0.3445 93.00 0.3734 . . 187 . . 'X-RAY DIFFRACTION' . 2.9317 2.9703 3244 0.3156 93.00 0.3211 . . 160 . . 'X-RAY DIFFRACTION' . 2.9703 3.0109 3243 0.3092 94.00 0.3293 . . 166 . . 'X-RAY DIFFRACTION' . 3.0109 3.0539 3449 0.3044 97.00 0.2713 . . 148 . . 'X-RAY DIFFRACTION' . 3.0539 3.0995 3390 0.2871 98.00 0.3014 . . 147 . . 'X-RAY DIFFRACTION' . 3.0995 3.1479 3436 0.2862 98.00 0.3171 . . 202 . . 'X-RAY DIFFRACTION' . 3.1479 3.1995 3408 0.2705 99.00 0.3089 . . 179 . . 'X-RAY DIFFRACTION' . 3.1995 3.2547 3492 0.2722 100.00 0.3281 . . 157 . . 'X-RAY DIFFRACTION' . 3.2547 3.3139 3483 0.2627 100.00 0.2969 . . 183 . . 'X-RAY DIFFRACTION' . 3.3139 3.3776 3438 0.2493 100.00 0.2925 . . 171 . . 'X-RAY DIFFRACTION' . 3.3776 3.4465 3492 0.2442 100.00 0.2454 . . 173 . . 'X-RAY DIFFRACTION' . 3.4465 3.5214 3482 0.2363 100.00 0.2566 . . 189 . . 'X-RAY DIFFRACTION' . 3.5214 3.6033 3454 0.2339 100.00 0.2643 . . 167 . . 'X-RAY DIFFRACTION' . 3.6033 3.6934 3464 0.2324 100.00 0.2730 . . 182 . . 'X-RAY DIFFRACTION' . 3.6934 3.7932 3465 0.2245 99.00 0.2581 . . 178 . . 'X-RAY DIFFRACTION' . 3.7932 3.9048 3416 0.2078 100.00 0.2423 . . 223 . . 'X-RAY DIFFRACTION' . 3.9048 4.0307 3461 0.2040 100.00 0.2601 . . 162 . . 'X-RAY DIFFRACTION' . 4.0307 4.1747 3493 0.1870 100.00 0.2391 . . 154 . . 'X-RAY DIFFRACTION' . 4.1747 4.3418 3460 0.1787 100.00 0.2034 . . 163 . . 'X-RAY DIFFRACTION' . 4.3418 4.5392 3460 0.1731 100.00 0.2013 . . 192 . . 'X-RAY DIFFRACTION' . 4.5392 4.7783 3470 0.1711 100.00 0.2279 . . 163 . . 'X-RAY DIFFRACTION' . 4.7783 5.0773 3488 0.1792 100.00 0.2177 . . 180 . . 'X-RAY DIFFRACTION' . 5.0773 5.4688 3440 0.1906 100.00 0.2316 . . 189 . . 'X-RAY DIFFRACTION' . 5.4688 6.0181 3474 0.2015 100.00 0.2426 . . 176 . . 'X-RAY DIFFRACTION' . 6.0181 6.8866 3430 0.2027 100.00 0.2223 . . 207 . . 'X-RAY DIFFRACTION' . 6.8866 8.6673 3464 0.1601 99.00 0.1879 . . 164 . . 'X-RAY DIFFRACTION' . 8.6673 46.7309 3318 0.2022 96.00 0.2115 . . 201 . . # _struct.entry_id 4XP9 _struct.title 'X-ray structure of Drosophila dopamine transporter bound to psychostimulant D-amphetamine' _struct.pdbx_descriptor 'Dopamine transporter-protein, Antibody fragment heavy chain-protein, Antibody fragment light chain-protein' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 4XP9 _struct_keywords.text ;integral membrane protein, all-alpha helical antidepressant complex, membrane protein, protein transport, transport protein-inhibitor complex ; _struct_keywords.pdbx_keywords 'transport protein/inhibitor' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 6 ? G N N 7 ? H N N 8 ? I N N 9 ? J N N 10 ? K N N 10 ? L N N 11 ? M N N 11 ? N N N 12 ? O N N 13 ? P N N 13 ? Q N N 13 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 GLY A 8 ? VAL A 21 ? GLY C 32 VAL C 45 1 ? 14 HELX_P HELX_P2 AA2 ASP A 22 ? ARG A 28 ? ASP C 46 ARG C 52 1 ? 7 HELX_P HELX_P3 AA3 ARG A 28 ? ASN A 36 ? ARG C 52 ASN C 60 1 ? 9 HELX_P HELX_P4 AA4 GLY A 37 ? ALA A 40 ? GLY C 61 ALA C 64 5 ? 4 HELX_P HELX_P5 AA5 PHE A 41 ? GLY A 52 ? PHE C 65 GLY C 76 1 ? 12 HELX_P HELX_P6 AA6 GLY A 52 ? ARG A 68 ? GLY C 76 ARG C 92 1 ? 17 HELX_P HELX_P7 AA7 GLY A 70 ? VAL A 79 ? GLY C 94 VAL C 103 1 ? 10 HELX_P HELX_P8 AA8 PRO A 80 ? PHE A 82 ? PRO C 104 PHE C 106 5 ? 3 HELX_P HELX_P9 AA9 LYS A 83 ? ALA A 113 ? LYS C 107 ALA C 137 1 ? 31 HELX_P HELX_P10 AB1 LEU A 119 ? SER A 123 ? LEU C 143 SER C 147 5 ? 5 HELX_P HELX_P11 AB2 SER A 145 ? TYR A 154 ? SER C 210 TYR C 219 1 ? 10 HELX_P HELX_P12 AB3 GLU A 157 ? SER A 161 ? GLU C 222 SER C 226 5 ? 5 HELX_P HELX_P13 AB4 LYS A 171 ? TRP A 190 ? LYS C 236 TRP C 255 1 ? 20 HELX_P HELX_P14 AB5 GLY A 192 ? THR A 220 ? GLY C 257 THR C 285 1 ? 29 HELX_P HELX_P15 AB6 GLY A 223 ? THR A 233 ? GLY C 288 THR C 298 1 ? 11 HELX_P HELX_P16 AB7 ASN A 235 ? TYR A 240 ? ASN C 300 TYR C 305 5 ? 6 HELX_P HELX_P17 AB8 LYS A 241 ? LEU A 256 ? LYS C 306 LEU C 321 1 ? 16 HELX_P HELX_P18 AB9 GLY A 261 ? SER A 268 ? GLY C 326 SER C 333 1 ? 8 HELX_P HELX_P19 AC1 ASN A 275 ? LEU A 309 ? ASN C 340 LEU C 374 1 ? 35 HELX_P HELX_P20 AC2 ARG A 312 ? ALA A 317 ? ARG C 377 ALA C 382 1 ? 6 HELX_P HELX_P21 AC3 GLY A 320 ? VAL A 326 ? GLY C 385 VAL C 391 1 ? 7 HELX_P HELX_P22 AC4 VAL A 326 ? THR A 334 ? VAL C 391 THR C 399 1 ? 9 HELX_P HELX_P23 AC5 ALA A 337 ? PHE A 372 ? ALA C 402 PHE C 437 1 ? 36 HELX_P HELX_P24 AC6 PHE A 372 ? ASN A 378 ? PHE C 437 ASN C 443 1 ? 7 HELX_P HELX_P25 AC7 ASN A 378 ? LEU A 395 ? ASN C 443 LEU C 460 1 ? 18 HELX_P HELX_P26 AC8 ALA A 396 ? THR A 399 ? ALA C 461 THR C 464 5 ? 4 HELX_P HELX_P27 AC9 GLY A 401 ? ALA A 413 ? GLY C 466 ALA C 478 1 ? 13 HELX_P HELX_P28 AD1 ALA A 414 ? ILE A 432 ? ALA C 479 ILE C 497 1 ? 19 HELX_P HELX_P29 AD2 GLY A 434 ? GLY A 447 ? GLY C 499 GLY C 512 1 ? 14 HELX_P HELX_P30 AD3 GLY A 451 ? PHE A 460 ? GLY C 516 PHE C 525 1 ? 10 HELX_P HELX_P31 AD4 PHE A 460 ? GLY A 476 ? PHE C 525 GLY C 541 1 ? 17 HELX_P HELX_P32 AD5 PRO A 488 ? VAL A 504 ? PRO C 553 VAL C 569 1 ? 17 HELX_P HELX_P33 AD6 VAL A 504 ? LEU A 515 ? VAL C 569 LEU C 580 1 ? 12 HELX_P HELX_P34 AD7 SER A 520 ? THR A 529 ? SER C 585 THR C 594 1 ? 10 HELX_P HELX_P35 AD8 PRO A 531 ? GLN A 536 ? PRO C 596 GLN C 601 1 ? 6 HELX_P HELX_P36 AD9 GLY B 30 ? SER B 32 ? GLY L 30 SER L 32 5 ? 3 HELX_P HELX_P37 AE1 GLU B 80 ? ALA B 84 ? GLU L 80 ALA L 84 5 ? 5 HELX_P HELX_P38 AE2 SER B 122 ? THR B 127 ? SER L 122 THR L 127 1 ? 6 HELX_P HELX_P39 AE3 LYS B 184 ? ARG B 189 ? LYS L 184 ARG L 189 1 ? 6 HELX_P HELX_P40 AE4 THR C 28 ? TYR C 32 ? THR H 28 TYR H 32 5 ? 5 HELX_P HELX_P41 AE5 ARG C 87 ? THR C 91 ? ARG H 87 THR H 91 5 ? 5 HELX_P HELX_P42 AE6 SER C 162 ? SER C 164 ? SER H 162 SER H 164 5 ? 3 HELX_P HELX_P43 AE7 PRO C 206 ? SER C 209 ? PRO H 206 SER H 209 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 124 SG ? ? ? 1_555 A CYS 133 SG ? ? C CYS 148 C CYS 157 1_555 ? ? ? ? ? ? ? 2.077 ? disulf2 disulf ? ? B CYS 23 SG ? ? ? 1_555 B CYS 89 SG ? ? L CYS 23 L CYS 89 1_555 ? ? ? ? ? ? ? 2.108 ? disulf3 disulf ? ? B CYS 135 SG ? ? ? 1_555 B CYS 195 SG ? ? L CYS 135 L CYS 195 1_555 ? ? ? ? ? ? ? 2.051 ? disulf4 disulf ? ? C CYS 22 SG ? ? ? 1_555 C CYS 96 SG ? ? H CYS 22 H CYS 96 1_555 ? ? ? ? ? ? ? 2.073 ? disulf5 disulf ? ? C CYS 146 SG ? ? ? 1_555 C CYS 201 SG ? ? H CYS 146 H CYS 201 1_555 ? ? ? ? ? ? ? 2.051 ? metalc1 metalc ? ? A GLY 18 O ? ? ? 1_555 M NA . NA ? ? C GLY 42 C NA 710 1_555 ? ? ? ? ? ? ? 2.276 ? metalc2 metalc ? ? A ALA 20 O ? ? ? 1_555 L NA . NA ? ? C ALA 44 C NA 709 1_555 ? ? ? ? ? ? ? 2.440 ? metalc3 metalc ? ? A VAL 21 O ? ? ? 1_555 M NA . NA ? ? C VAL 45 C NA 710 1_555 ? ? ? ? ? ? ? 2.546 ? metalc4 metalc ? ? A ASN 25 OD1 ? ? ? 1_555 L NA . NA ? ? C ASN 49 C NA 709 1_555 ? ? ? ? ? ? ? 2.403 ? covale1 covale one ? A ASN 117 ND2 ? ? ? 1_555 E NAG . C1 ? ? C ASN 141 C NAG 702 1_555 ? ? ? ? ? ? ? 1.471 ? metalc5 metalc ? ? A SER 255 O ? ? ? 1_555 L NA . NA ? ? C SER 320 C NA 709 1_555 ? ? ? ? ? ? ? 2.788 ? metalc6 metalc ? ? A SER 255 OG ? ? ? 1_555 L NA . NA ? ? C SER 320 C NA 709 1_555 ? ? ? ? ? ? ? 2.332 ? metalc7 metalc ? ? A ASN 287 OD1 ? ? ? 1_555 L NA . NA ? ? C ASN 352 C NA 709 1_555 ? ? ? ? ? ? ? 2.772 ? metalc8 metalc ? ? A LEU 352 O ? ? ? 1_555 M NA . NA ? ? C LEU 417 C NA 710 1_555 ? ? ? ? ? ? ? 2.339 ? metalc9 metalc ? ? A ASP 355 OD2 ? ? ? 1_555 M NA . NA ? ? C ASP 420 C NA 710 1_555 ? ? ? ? ? ? ? 2.923 ? metalc10 metalc ? ? A SER 356 OG ? ? ? 1_555 M NA . NA ? ? C SER 421 C NA 710 1_555 ? ? ? ? ? ? ? 2.647 ? metalc11 metalc ? ? L NA . NA ? ? ? 1_555 O HOH . O ? ? C NA 709 C HOH 805 1_555 ? ? ? ? ? ? ? 2.715 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ASP 1 A . ? ASP 25 C GLU 2 A ? GLU 26 C 1 0.05 2 SER 7 B . ? SER 7 L PRO 8 B ? PRO 8 L 1 -5.00 3 TYR 95 B . ? TYR 95 L PRO 96 B ? PRO 96 L 1 -3.86 4 TYR 141 B . ? TYR 141 L PRO 142 B ? PRO 142 L 1 -0.61 5 GLY 135 C . ? GLY 135 H ASP 136 C ? ASP 136 H 1 -22.33 6 THR 137 C . ? THR 137 H THR 138 C ? THR 138 H 1 -17.76 7 THR 138 C . ? THR 138 H GLY 139 C ? GLY 139 H 1 3.59 8 PHE 152 C . ? PHE 152 H PRO 153 C ? PRO 153 H 1 -4.73 9 GLU 154 C . ? GLU 154 H PRO 155 C ? PRO 155 H 1 4.58 10 TRP 194 C . ? TRP 194 H PRO 195 C ? PRO 195 H 1 -3.65 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 2 ? AA2 ? 4 ? AA3 ? 6 ? AA4 ? 4 ? AA5 ? 4 ? AA6 ? 4 ? AA7 ? 4 ? AA8 ? 6 ? AA9 ? 4 ? AB1 ? 4 ? AB2 ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA2 1 2 ? anti-parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA3 1 2 ? parallel AA3 2 3 ? anti-parallel AA3 3 4 ? anti-parallel AA3 4 5 ? anti-parallel AA3 5 6 ? anti-parallel AA4 1 2 ? parallel AA4 2 3 ? anti-parallel AA4 3 4 ? anti-parallel AA5 1 2 ? anti-parallel AA5 2 3 ? anti-parallel AA5 3 4 ? anti-parallel AA6 1 2 ? anti-parallel AA6 2 3 ? anti-parallel AA6 3 4 ? anti-parallel AA7 1 2 ? anti-parallel AA7 2 3 ? anti-parallel AA7 3 4 ? anti-parallel AA8 1 2 ? parallel AA8 2 3 ? anti-parallel AA8 3 4 ? anti-parallel AA8 4 5 ? anti-parallel AA8 5 6 ? anti-parallel AA9 1 2 ? parallel AA9 2 3 ? anti-parallel AA9 3 4 ? anti-parallel AB1 1 2 ? anti-parallel AB1 2 3 ? anti-parallel AB1 3 4 ? anti-parallel AB2 1 2 ? anti-parallel AB2 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 THR A 481 ? TYR A 482 ? THR C 546 TYR C 547 AA1 2 TYR A 485 ? VAL A 486 ? TYR C 550 VAL C 551 AA2 1 LEU B 4 ? SER B 7 ? LEU L 4 SER L 7 AA2 2 VAL B 19 ? ALA B 25 ? VAL L 19 ALA L 25 AA2 3 SER B 71 ? ILE B 76 ? SER L 71 ILE L 76 AA2 4 PHE B 63 ? SER B 68 ? PHE L 63 SER L 68 AA3 1 ILE B 10 ? THR B 13 ? ILE L 10 THR L 13 AA3 2 THR B 103 ? MET B 107 ? THR L 103 MET L 107 AA3 3 THR B 86 ? GLN B 91 ? THR L 86 GLN L 91 AA3 4 LEU B 34 ? GLN B 39 ? LEU L 34 GLN L 39 AA3 5 LYS B 46 ? TYR B 50 ? LYS L 46 TYR L 50 AA3 6 ASN B 54 ? LEU B 55 ? ASN L 54 LEU L 55 AA4 1 ILE B 10 ? THR B 13 ? ILE L 10 THR L 13 AA4 2 THR B 103 ? MET B 107 ? THR L 103 MET L 107 AA4 3 THR B 86 ? GLN B 91 ? THR L 86 GLN L 91 AA4 4 THR B 98 ? PHE B 99 ? THR L 98 PHE L 99 AA5 1 THR B 115 ? PHE B 119 ? THR L 115 PHE L 119 AA5 2 GLY B 130 ? PHE B 140 ? GLY L 130 PHE L 140 AA5 3 TYR B 174 ? THR B 183 ? TYR L 174 THR L 183 AA5 4 VAL B 160 ? TRP B 164 ? VAL L 160 TRP L 164 AA6 1 SER B 154 ? ARG B 156 ? SER L 154 ARG L 156 AA6 2 ILE B 145 ? ILE B 151 ? ILE L 145 ILE L 151 AA6 3 SER B 192 ? HIS B 199 ? SER L 192 HIS L 199 AA6 4 SER B 202 ? ASN B 211 ? SER L 202 ASN L 211 AA7 1 GLU C 6 ? SER C 7 ? GLU H 6 SER H 7 AA7 2 LYS C 19 ? ALA C 23 ? LYS H 19 ALA H 23 AA7 3 ILE C 78 ? GLU C 82 ? ILE H 78 GLU H 82 AA7 4 THR C 69 ? ASP C 73 ? THR H 69 ASP H 73 AA8 1 LEU C 11 ? VAL C 12 ? LEU H 11 VAL H 12 AA8 2 THR C 113 ? VAL C 117 ? THR H 113 VAL H 117 AA8 3 ALA C 92 ? ARG C 98 ? ALA H 92 ARG H 98 AA8 4 MET C 34 ? GLN C 39 ? MET H 34 GLN H 39 AA8 5 LEU C 45 ? ILE C 51 ? LEU H 45 ILE H 51 AA8 6 ILE C 58 ? TYR C 60 ? ILE H 58 TYR H 60 AA9 1 LEU C 11 ? VAL C 12 ? LEU H 11 VAL H 12 AA9 2 THR C 113 ? VAL C 117 ? THR H 113 VAL H 117 AA9 3 ALA C 92 ? ARG C 98 ? ALA H 92 ARG H 98 AA9 4 TYR C 108 ? TRP C 109 ? TYR H 108 TRP H 109 AB1 1 SER C 126 ? LEU C 130 ? SER H 126 LEU H 130 AB1 2 SER C 141 ? TYR C 151 ? SER H 141 TYR H 151 AB1 3 TYR C 181 ? THR C 190 ? TYR H 181 THR H 190 AB1 4 VAL C 169 ? LEU C 176 ? VAL H 169 LEU H 176 AB2 1 THR C 157 ? TRP C 160 ? THR H 157 TRP H 160 AB2 2 THR C 200 ? HIS C 205 ? THR H 200 HIS H 205 AB2 3 THR C 210 ? LYS C 215 ? THR H 210 LYS H 215 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N TYR A 482 ? N TYR C 547 O TYR A 485 ? O TYR C 550 AA2 1 2 N THR B 5 ? N THR L 5 O ARG B 24 ? O ARG L 24 AA2 2 3 N CYS B 23 ? N CYS L 23 O TYR B 72 ? O TYR L 72 AA2 3 4 O SER B 73 ? O SER L 73 N SER B 66 ? N SER L 66 AA3 1 2 N MET B 11 ? N MET L 11 O GLU B 106 ? O GLU L 106 AA3 2 3 O THR B 103 ? O THR L 103 N TYR B 87 ? N TYR L 87 AA3 3 4 O TYR B 88 ? O TYR L 88 N TYR B 37 ? N TYR L 37 AA3 4 5 N TRP B 36 ? N TRP L 36 O ILE B 49 ? O ILE L 49 AA3 5 6 N TYR B 50 ? N TYR L 50 O ASN B 54 ? O ASN L 54 AA4 1 2 N MET B 11 ? N MET L 11 O GLU B 106 ? O GLU L 106 AA4 2 3 O THR B 103 ? O THR L 103 N TYR B 87 ? N TYR L 87 AA4 3 4 N GLN B 91 ? N GLN L 91 O THR B 98 ? O THR L 98 AA5 1 2 N PHE B 119 ? N PHE L 119 O VAL B 134 ? O VAL L 134 AA5 2 3 N ALA B 131 ? N ALA L 131 O LEU B 182 ? O LEU L 182 AA5 3 4 O THR B 179 ? O THR L 179 N LEU B 161 ? N LEU L 161 AA6 1 2 O ARG B 156 ? O ARG L 156 N TRP B 149 ? N TRP L 149 AA6 2 3 N LYS B 150 ? N LYS L 150 O THR B 194 ? O THR L 194 AA6 3 4 N ALA B 197 ? N ALA L 197 O ILE B 206 ? O ILE L 206 AA7 1 2 N SER C 7 ? N SER H 7 O SER C 21 ? O SER H 21 AA7 2 3 N CYS C 22 ? N CYS H 22 O LEU C 79 ? O LEU H 79 AA7 3 4 O GLU C 82 ? O GLU H 82 N THR C 69 ? N THR H 69 AA8 1 2 N VAL C 12 ? N VAL H 12 O THR C 116 ? O THR H 116 AA8 2 3 O THR C 113 ? O THR H 113 N TYR C 94 ? N TYR H 94 AA8 3 4 O TYR C 95 ? O TYR H 95 N VAL C 37 ? N VAL H 37 AA8 4 5 N MET C 34 ? N MET H 34 O ILE C 51 ? O ILE H 51 AA8 5 6 N GLU C 50 ? N GLU H 50 O TYR C 59 ? O TYR H 59 AA9 1 2 N VAL C 12 ? N VAL H 12 O THR C 116 ? O THR H 116 AA9 2 3 O THR C 113 ? O THR H 113 N TYR C 94 ? N TYR H 94 AA9 3 4 N ARG C 98 ? N ARG H 98 O TYR C 108 ? O TYR H 108 AB1 1 2 N TYR C 128 ? N TYR H 128 O LEU C 147 ? O LEU H 147 AB1 2 3 N LEU C 144 ? N LEU H 144 O VAL C 187 ? O VAL H 187 AB1 3 4 O SER C 186 ? O SER H 186 N HIS C 170 ? N HIS H 170 AB2 1 2 N THR C 157 ? N THR H 157 O ALA C 204 ? O ALA H 204 AB2 2 3 N VAL C 203 ? N VAL H 203 O VAL C 212 ? O VAL H 212 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software C Y01 701 ? 5 'binding site for residue Y01 C 701' AC2 Software C MAL 703 ? 4 'binding site for residue MAL C 703' AC3 Software C MPO 704 ? 1 'binding site for residue MPO C 704' AC4 Software C CLR 705 ? 5 'binding site for residue CLR C 705' AC5 Software C 1WE 706 ? 9 'binding site for residue 1WE C 706' AC6 Software C P4G 707 ? 1 'binding site for residue P4G C 707' AC7 Software C NA 709 ? 5 'binding site for residue NA C 709' AC8 Software C NA 710 ? 5 'binding site for residue NA C 710' AC9 Software C CL 711 ? 4 'binding site for residue CL C 711' AD1 Software C NAG 702 ? 2 'binding site for Mono-Saccharide NAG C 702 bound to ASN C 141' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 5 TYR A 277 ? TYR C 342 . ? 1_555 ? 2 AC1 5 PHE A 285 ? PHE C 350 . ? 1_555 ? 3 AC1 5 GLY A 451 ? GLY C 516 . ? 1_555 ? 4 AC1 5 TYR A 453 ? TYR C 518 . ? 1_555 ? 5 AC1 5 TRP A 454 ? TRP C 519 . ? 1_555 ? 6 AC2 4 ARG A 109 ? ARG C 133 . ? 1_555 ? 7 AC2 4 ALA A 113 ? ALA C 137 . ? 1_555 ? 8 AC2 4 PRO A 120 ? PRO C 144 . ? 1_555 ? 9 AC2 4 TYR A 154 ? TYR C 219 . ? 1_555 ? 10 AC3 1 GLU A 157 ? GLU C 222 . ? 1_555 ? 11 AC4 5 VAL A 10 ? VAL C 34 . ? 1_555 ? 12 AC4 5 LEU A 13 ? LEU C 37 . ? 1_555 ? 13 AC4 5 LEU A 205 ? LEU C 270 . ? 1_555 ? 14 AC4 5 TYR A 208 ? TYR C 273 . ? 1_555 ? 15 AC4 5 ILE A 286 ? ILE C 351 . ? 1_555 ? 16 AC5 9 PHE A 19 ? PHE C 43 . ? 1_555 ? 17 AC5 9 ALA A 20 ? ALA C 44 . ? 1_555 ? 18 AC5 9 ASP A 22 ? ASP C 46 . ? 1_555 ? 19 AC5 9 PHE A 254 ? PHE C 319 . ? 1_555 ? 20 AC5 9 SER A 255 ? SER C 320 . ? 1_555 ? 21 AC5 9 LEU A 256 ? LEU C 321 . ? 1_555 ? 22 AC5 9 GLY A 257 ? GLY C 322 . ? 1_555 ? 23 AC5 9 PHE A 260 ? PHE C 325 . ? 1_555 ? 24 AC5 9 HOH O . ? HOH C 805 . ? 1_555 ? 25 AC6 1 PHE A 512 ? PHE C 577 . ? 1_555 ? 26 AC7 5 ALA A 20 ? ALA C 44 . ? 1_555 ? 27 AC7 5 ASN A 25 ? ASN C 49 . ? 1_555 ? 28 AC7 5 SER A 255 ? SER C 320 . ? 1_555 ? 29 AC7 5 ASN A 287 ? ASN C 352 . ? 1_555 ? 30 AC7 5 HOH O . ? HOH C 805 . ? 1_555 ? 31 AC8 5 GLY A 18 ? GLY C 42 . ? 1_555 ? 32 AC8 5 VAL A 21 ? VAL C 45 . ? 1_555 ? 33 AC8 5 LEU A 352 ? LEU C 417 . ? 1_555 ? 34 AC8 5 ASP A 355 ? ASP C 420 . ? 1_555 ? 35 AC8 5 SER A 356 ? SER C 421 . ? 1_555 ? 36 AC9 4 TYR A 45 ? TYR C 69 . ? 1_555 ? 37 AC9 4 GLN A 251 ? GLN C 316 . ? 1_555 ? 38 AC9 4 SER A 255 ? SER C 320 . ? 1_555 ? 39 AC9 4 SER A 291 ? SER C 356 . ? 1_555 ? 40 AD1 2 THR A 116 ? THR C 140 . ? 1_555 ? 41 AD1 2 ASN A 117 ? ASN C 141 . ? 1_555 ? # _atom_sites.entry_id 4XP9 _atom_sites.fract_transf_matrix[1][1] 0.010272 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.007105 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.005997 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C CL H N NA O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ASP A 1 1 ? -167.059 -165.502 205.215 1.00 126.43 ? 25 ASP C N 1 ATOM 2 C CA . ASP A 1 1 ? -166.425 -166.799 205.414 1.00 133.94 ? 25 ASP C CA 1 ATOM 3 C C . ASP A 1 1 ? -167.318 -167.911 204.859 1.00 140.31 ? 25 ASP C C 1 ATOM 4 O O . ASP A 1 1 ? -168.480 -168.035 205.261 1.00 139.57 ? 25 ASP C O 1 ATOM 5 C CB . ASP A 1 1 ? -166.140 -167.032 206.903 1.00 135.37 ? 25 ASP C CB 1 ATOM 6 C CG . ASP A 1 1 ? -164.929 -167.933 207.147 1.00 136.83 ? 25 ASP C CG 1 ATOM 7 O OD1 . ASP A 1 1 ? -164.494 -168.633 206.206 1.00 138.00 ? 25 ASP C OD1 1 ATOM 8 O OD2 . ASP A 1 1 ? -164.413 -167.943 208.289 1.00 129.92 ? 25 ASP C OD2 1 ATOM 9 N N . GLU A 1 2 ? -166.779 -168.728 203.947 1.00 139.39 ? 26 GLU C N 1 ATOM 10 C CA . GLU A 1 2 ? -165.397 -168.602 203.471 1.00 131.15 ? 26 GLU C CA 1 ATOM 11 C C . GLU A 1 2 ? -165.155 -167.364 202.610 1.00 126.29 ? 26 GLU C C 1 ATOM 12 O O . GLU A 1 2 ? -165.954 -167.027 201.735 1.00 124.24 ? 26 GLU C O 1 ATOM 13 C CB . GLU A 1 2 ? -164.995 -169.849 202.671 1.00 132.80 ? 26 GLU C CB 1 ATOM 14 C CG . GLU A 1 2 ? -164.674 -171.072 203.523 1.00 136.04 ? 26 GLU C CG 1 ATOM 15 C CD . GLU A 1 2 ? -164.204 -172.260 202.691 1.00 136.79 ? 26 GLU C CD 1 ATOM 16 O OE1 . GLU A 1 2 ? -164.229 -172.175 201.444 1.00 129.44 ? 26 GLU C OE1 1 ATOM 17 O OE2 . GLU A 1 2 ? -163.808 -173.283 203.286 1.00 137.99 ? 26 GLU C OE2 1 ATOM 18 N N . ARG A 1 3 ? -164.022 -166.711 202.854 1.00 120.34 ? 27 ARG C N 1 ATOM 19 C CA . ARG A 1 3 ? -163.595 -165.589 202.034 1.00 105.71 ? 27 ARG C CA 1 ATOM 20 C C . ARG A 1 3 ? -162.170 -165.836 201.577 1.00 98.41 ? 27 ARG C C 1 ATOM 21 O O . ARG A 1 3 ? -161.332 -166.316 202.345 1.00 102.48 ? 27 ARG C O 1 ATOM 22 C CB . ARG A 1 3 ? -163.698 -164.271 202.804 1.00 105.88 ? 27 ARG C CB 1 ATOM 23 C CG . ARG A 1 3 ? -163.343 -163.031 201.984 1.00 98.97 ? 27 ARG C CG 1 ATOM 24 C CD . ARG A 1 3 ? -163.628 -161.748 202.755 1.00 91.91 ? 27 ARG C CD 1 ATOM 25 N NE . ARG A 1 3 ? -163.208 -160.559 202.021 1.00 92.48 ? 27 ARG C NE 1 ATOM 26 C CZ . ARG A 1 3 ? -164.037 -159.650 201.514 1.00 94.93 ? 27 ARG C CZ 1 ATOM 27 N NH1 . ARG A 1 3 ? -165.350 -159.781 201.660 1.00 96.17 ? 27 ARG C NH1 1 ATOM 28 N NH2 . ARG A 1 3 ? -163.552 -158.598 200.865 1.00 94.51 ? 27 ARG C NH2 1 ATOM 29 N N . GLU A 1 4 ? -161.905 -165.484 200.329 1.00 94.59 ? 28 GLU C N 1 ATOM 30 C CA . GLU A 1 4 ? -160.619 -165.714 199.684 1.00 94.90 ? 28 GLU C CA 1 ATOM 31 C C . GLU A 1 4 ? -159.507 -164.974 200.444 1.00 93.63 ? 28 GLU C C 1 ATOM 32 O O . GLU A 1 4 ? -159.757 -163.935 201.047 1.00 96.78 ? 28 GLU C O 1 ATOM 33 C CB . GLU A 1 4 ? -160.724 -165.258 198.227 1.00 94.35 ? 28 GLU C CB 1 ATOM 34 C CG . GLU A 1 4 ? -159.548 -165.512 197.329 1.00 96.24 ? 28 GLU C CG 1 ATOM 35 C CD . GLU A 1 4 ? -159.806 -164.920 195.953 1.00 106.41 ? 28 GLU C CD 1 ATOM 36 O OE1 . GLU A 1 4 ? -160.954 -164.464 195.744 1.00 108.60 ? 28 GLU C OE1 1 ATOM 37 O OE2 . GLU A 1 4 ? -158.887 -164.897 195.096 1.00 103.05 ? 28 GLU C OE2 1 ATOM 38 N N . THR A 1 5 ? -158.295 -165.518 200.458 1.00 87.30 ? 29 THR C N 1 ATOM 39 C CA . THR A 1 5 ? -157.215 -164.921 201.246 1.00 85.32 ? 29 THR C CA 1 ATOM 40 C C . THR A 1 5 ? -155.945 -164.742 200.414 1.00 88.07 ? 29 THR C C 1 ATOM 41 O O . THR A 1 5 ? -155.779 -165.392 199.377 1.00 89.99 ? 29 THR C O 1 ATOM 42 C CB . THR A 1 5 ? -156.882 -165.774 202.479 1.00 89.25 ? 29 THR C CB 1 ATOM 43 O OG1 . THR A 1 5 ? -155.828 -165.155 203.225 1.00 95.20 ? 29 THR C OG1 1 ATOM 44 C CG2 . THR A 1 5 ? -156.426 -167.164 202.053 1.00 93.77 ? 29 THR C CG2 1 ATOM 45 N N . TRP A 1 6 ? -155.047 -163.867 200.864 1.00 85.56 ? 30 TRP C N 1 ATOM 46 C CA . TRP A 1 6 ? -153.832 -163.599 200.101 1.00 85.92 ? 30 TRP C CA 1 ATOM 47 C C . TRP A 1 6 ? -153.061 -164.899 199.931 1.00 87.39 ? 30 TRP C C 1 ATOM 48 O O . TRP A 1 6 ? -152.916 -165.684 200.868 1.00 95.25 ? 30 TRP C O 1 ATOM 49 C CB . TRP A 1 6 ? -152.954 -162.531 200.775 1.00 79.94 ? 30 TRP C CB 1 ATOM 50 C CG . TRP A 1 6 ? -153.561 -161.141 200.801 1.00 82.35 ? 30 TRP C CG 1 ATOM 51 C CD1 . TRP A 1 6 ? -154.129 -160.507 201.884 1.00 79.03 ? 30 TRP C CD1 1 ATOM 52 C CD2 . TRP A 1 6 ? -153.664 -160.218 199.709 1.00 87.31 ? 30 TRP C CD2 1 ATOM 53 N NE1 . TRP A 1 6 ? -154.576 -159.260 201.531 1.00 78.11 ? 30 TRP C NE1 1 ATOM 54 C CE2 . TRP A 1 6 ? -154.307 -159.054 200.202 1.00 85.48 ? 30 TRP C CE2 1 ATOM 55 C CE3 . TRP A 1 6 ? -153.282 -160.259 198.363 1.00 85.22 ? 30 TRP C CE3 1 ATOM 56 C CZ2 . TRP A 1 6 ? -154.572 -157.944 199.390 1.00 82.10 ? 30 TRP C CZ2 1 ATOM 57 C CZ3 . TRP A 1 6 ? -153.550 -159.158 197.561 1.00 81.43 ? 30 TRP C CZ3 1 ATOM 58 C CH2 . TRP A 1 6 ? -154.186 -158.019 198.076 1.00 79.73 ? 30 TRP C CH2 1 ATOM 59 N N . SER A 1 7 ? -152.557 -165.115 198.727 1.00 90.38 ? 31 SER C N 1 ATOM 60 C CA . SER A 1 7 ? -151.818 -166.321 198.409 1.00 87.17 ? 31 SER C CA 1 ATOM 61 C C . SER A 1 7 ? -150.541 -166.381 199.242 1.00 87.96 ? 31 SER C C 1 ATOM 62 O O . SER A 1 7 ? -149.924 -167.433 199.370 1.00 101.43 ? 31 SER C O 1 ATOM 63 C CB . SER A 1 7 ? -151.500 -166.368 196.924 1.00 90.27 ? 31 SER C CB 1 ATOM 64 O OG . SER A 1 7 ? -150.747 -167.521 196.614 1.00 106.46 ? 31 SER C OG 1 ATOM 65 N N . GLY A 1 8 ? -150.143 -165.239 199.791 1.00 85.48 ? 32 GLY C N 1 ATOM 66 C CA . GLY A 1 8 ? -149.020 -165.153 200.711 1.00 88.73 ? 32 GLY C CA 1 ATOM 67 C C . GLY A 1 8 ? -148.920 -163.733 201.244 1.00 90.27 ? 32 GLY C C 1 ATOM 68 O O . GLY A 1 8 ? -149.368 -162.791 200.580 1.00 92.67 ? 32 GLY C O 1 ATOM 69 N N . LYS A 1 9 ? -148.329 -163.558 202.426 1.00 84.12 ? 33 LYS C N 1 ATOM 70 C CA . LYS A 1 9 ? -148.349 -162.239 203.061 1.00 86.02 ? 33 LYS C CA 1 ATOM 71 C C . LYS A 1 9 ? -147.564 -161.192 202.254 1.00 83.62 ? 33 LYS C C 1 ATOM 72 O O . LYS A 1 9 ? -147.942 -160.020 202.218 1.00 80.48 ? 33 LYS C O 1 ATOM 73 C CB . LYS A 1 9 ? -147.823 -162.318 204.500 1.00 74.57 ? 33 LYS C CB 1 ATOM 74 N N . VAL A 1 10 ? -146.508 -161.603 201.565 1.00 81.80 ? 34 VAL C N 1 ATOM 75 C CA . VAL A 1 10 ? -145.771 -160.638 200.755 1.00 80.22 ? 34 VAL C CA 1 ATOM 76 C C . VAL A 1 10 ? -146.651 -160.015 199.671 1.00 82.25 ? 34 VAL C C 1 ATOM 77 O O . VAL A 1 10 ? -146.495 -158.835 199.347 1.00 85.64 ? 34 VAL C O 1 ATOM 78 C CB . VAL A 1 10 ? -144.540 -161.269 200.120 1.00 77.95 ? 34 VAL C CB 1 ATOM 79 C CG1 . VAL A 1 10 ? -143.960 -160.350 199.046 1.00 78.53 ? 34 VAL C CG1 1 ATOM 80 C CG2 . VAL A 1 10 ? -143.526 -161.537 201.208 1.00 85.26 ? 34 VAL C CG2 1 ATOM 81 N N . ASP A 1 11 ? -147.604 -160.776 199.147 1.00 78.39 ? 35 ASP C N 1 ATOM 82 C CA . ASP A 1 11 ? -148.531 -160.231 198.164 1.00 82.44 ? 35 ASP C CA 1 ATOM 83 C C . ASP A 1 11 ? -149.302 -159.044 198.747 1.00 85.30 ? 35 ASP C C 1 ATOM 84 O O . ASP A 1 11 ? -149.464 -158.008 198.089 1.00 81.86 ? 35 ASP C O 1 ATOM 85 C CB . ASP A 1 11 ? -149.515 -161.302 197.703 1.00 85.14 ? 35 ASP C CB 1 ATOM 86 C CG . ASP A 1 11 ? -148.840 -162.430 196.952 1.00 87.34 ? 35 ASP C CG 1 ATOM 87 O OD1 . ASP A 1 11 ? -147.592 -162.400 196.827 1.00 85.28 ? 35 ASP C OD1 1 ATOM 88 O OD2 . ASP A 1 11 ? -149.559 -163.354 196.498 1.00 88.83 ? 35 ASP C OD2 1 ATOM 89 N N . PHE A 1 12 ? -149.748 -159.182 199.993 1.00 85.00 ? 36 PHE C N 1 ATOM 90 C CA . PHE A 1 12 ? -150.531 -158.131 200.615 1.00 81.04 ? 36 PHE C CA 1 ATOM 91 C C . PHE A 1 12 ? -149.664 -156.898 200.776 1.00 80.28 ? 36 PHE C C 1 ATOM 92 O O . PHE A 1 12 ? -150.066 -155.783 200.419 1.00 78.74 ? 36 PHE C O 1 ATOM 93 C CB . PHE A 1 12 ? -151.070 -158.588 201.965 1.00 75.53 ? 36 PHE C CB 1 ATOM 94 C CG . PHE A 1 12 ? -151.592 -157.475 202.823 1.00 71.34 ? 36 PHE C CG 1 ATOM 95 C CD1 . PHE A 1 12 ? -152.788 -156.854 202.518 1.00 76.62 ? 36 PHE C CD1 1 ATOM 96 C CD2 . PHE A 1 12 ? -150.894 -157.063 203.944 1.00 70.46 ? 36 PHE C CD2 1 ATOM 97 C CE1 . PHE A 1 12 ? -153.282 -155.836 203.315 1.00 74.22 ? 36 PHE C CE1 1 ATOM 98 C CE2 . PHE A 1 12 ? -151.377 -156.052 204.748 1.00 70.57 ? 36 PHE C CE2 1 ATOM 99 C CZ . PHE A 1 12 ? -152.577 -155.432 204.426 1.00 74.21 ? 36 PHE C CZ 1 ATOM 100 N N . LEU A 1 13 ? -148.458 -157.104 201.289 1.00 78.44 ? 37 LEU C N 1 ATOM 101 C CA . LEU A 1 13 ? -147.596 -155.978 201.592 1.00 80.92 ? 37 LEU C CA 1 ATOM 102 C C . LEU A 1 13 ? -147.225 -155.226 200.333 1.00 78.83 ? 37 LEU C C 1 ATOM 103 O O . LEU A 1 13 ? -147.120 -154.006 200.347 1.00 82.35 ? 37 LEU C O 1 ATOM 104 C CB . LEU A 1 13 ? -146.329 -156.443 202.302 1.00 80.73 ? 37 LEU C CB 1 ATOM 105 C CG . LEU A 1 13 ? -146.525 -157.129 203.646 1.00 72.46 ? 37 LEU C CG 1 ATOM 106 C CD1 . LEU A 1 13 ? -145.167 -157.462 204.194 1.00 71.63 ? 37 LEU C CD1 1 ATOM 107 C CD2 . LEU A 1 13 ? -147.282 -156.230 204.589 1.00 74.13 ? 37 LEU C CD2 1 ATOM 108 N N . LEU A 1 14 ? -147.041 -155.951 199.239 1.00 75.22 ? 38 LEU C N 1 ATOM 109 C CA . LEU A 1 14 ? -146.667 -155.297 197.998 1.00 75.70 ? 38 LEU C CA 1 ATOM 110 C C . LEU A 1 14 ? -147.867 -154.601 197.374 1.00 76.71 ? 38 LEU C C 1 ATOM 111 O O . LEU A 1 14 ? -147.724 -153.553 196.754 1.00 79.11 ? 38 LEU C O 1 ATOM 112 C CB . LEU A 1 14 ? -146.055 -156.295 197.020 1.00 76.77 ? 38 LEU C CB 1 ATOM 113 C CG . LEU A 1 14 ? -144.731 -156.912 197.466 1.00 76.38 ? 38 LEU C CG 1 ATOM 114 C CD1 . LEU A 1 14 ? -144.252 -157.942 196.455 1.00 83.78 ? 38 LEU C CD1 1 ATOM 115 C CD2 . LEU A 1 14 ? -143.696 -155.833 197.667 1.00 70.57 ? 38 LEU C CD2 1 ATOM 116 N N . SER A 1 15 ? -149.054 -155.177 197.533 1.00 77.01 ? 39 SER C N 1 ATOM 117 C CA . SER A 1 15 ? -150.258 -154.505 197.074 1.00 75.40 ? 39 SER C CA 1 ATOM 118 C C . SER A 1 15 ? -150.440 -153.190 197.791 1.00 74.30 ? 39 SER C C 1 ATOM 119 O O . SER A 1 15 ? -150.866 -152.201 197.205 1.00 78.70 ? 39 SER C O 1 ATOM 120 C CB . SER A 1 15 ? -151.481 -155.369 197.310 1.00 74.25 ? 39 SER C CB 1 ATOM 121 O OG . SER A 1 15 ? -151.390 -156.538 196.531 1.00 81.28 ? 39 SER C OG 1 ATOM 122 N N . VAL A 1 16 ? -150.100 -153.171 199.066 1.00 74.37 ? 40 VAL C N 1 ATOM 123 C CA . VAL A 1 16 ? -150.270 -151.965 199.839 1.00 72.07 ? 40 VAL C CA 1 ATOM 124 C C . VAL A 1 16 ? -149.189 -150.966 199.538 1.00 72.12 ? 40 VAL C C 1 ATOM 125 O O . VAL A 1 16 ? -149.460 -149.777 199.408 1.00 70.41 ? 40 VAL C O 1 ATOM 126 C CB . VAL A 1 16 ? -150.257 -152.251 201.320 1.00 71.17 ? 40 VAL C CB 1 ATOM 127 C CG1 . VAL A 1 16 ? -150.098 -150.943 202.076 1.00 63.63 ? 40 VAL C CG1 1 ATOM 128 C CG2 . VAL A 1 16 ? -151.538 -152.972 201.703 1.00 69.92 ? 40 VAL C CG2 1 ATOM 129 N N . ILE A 1 17 ? -147.953 -151.445 199.461 1.00 73.99 ? 41 ILE C N 1 ATOM 130 C CA . ILE A 1 17 ? -146.841 -150.565 199.157 1.00 70.65 ? 41 ILE C CA 1 ATOM 131 C C . ILE A 1 17 ? -146.999 -150.030 197.740 1.00 73.46 ? 41 ILE C C 1 ATOM 132 O O . ILE A 1 17 ? -146.680 -148.871 197.458 1.00 74.37 ? 41 ILE C O 1 ATOM 133 C CB . ILE A 1 17 ? -145.495 -151.281 199.301 1.00 70.68 ? 41 ILE C CB 1 ATOM 134 C CG1 . ILE A 1 17 ? -145.238 -151.641 200.768 1.00 71.35 ? 41 ILE C CG1 1 ATOM 135 C CG2 . ILE A 1 17 ? -144.386 -150.404 198.797 1.00 67.30 ? 41 ILE C CG2 1 ATOM 136 C CD1 . ILE A 1 17 ? -143.943 -152.413 200.980 1.00 69.90 ? 41 ILE C CD1 1 ATOM 137 N N . GLY A 1 18 ? -147.546 -150.863 196.859 1.00 72.25 ? 42 GLY C N 1 ATOM 138 C CA . GLY A 1 18 ? -147.728 -150.449 195.485 1.00 71.32 ? 42 GLY C CA 1 ATOM 139 C C . GLY A 1 18 ? -148.815 -149.402 195.372 1.00 72.24 ? 42 GLY C C 1 ATOM 140 O O . GLY A 1 18 ? -148.720 -148.483 194.569 1.00 77.22 ? 42 GLY C O 1 ATOM 141 N N . PHE A 1 19 ? -149.854 -149.531 196.179 1.00 71.02 ? 43 PHE C N 1 ATOM 142 C CA . PHE A 1 19 ? -150.923 -148.555 196.149 1.00 71.86 ? 43 PHE C CA 1 ATOM 143 C C . PHE A 1 19 ? -150.384 -147.215 196.652 1.00 73.75 ? 43 PHE C C 1 ATOM 144 O O . PHE A 1 19 ? -150.572 -146.174 196.032 1.00 73.90 ? 43 PHE C O 1 ATOM 145 C CB . PHE A 1 19 ? -152.104 -149.037 196.995 1.00 63.73 ? 43 PHE C CB 1 ATOM 146 C CG . PHE A 1 19 ? -153.088 -147.963 197.336 1.00 67.61 ? 43 PHE C CG 1 ATOM 147 C CD1 . PHE A 1 19 ? -153.935 -147.446 196.367 1.00 72.90 ? 43 PHE C CD1 1 ATOM 148 C CD2 . PHE A 1 19 ? -153.186 -147.482 198.636 1.00 68.48 ? 43 PHE C CD2 1 ATOM 149 C CE1 . PHE A 1 19 ? -154.856 -146.454 196.682 1.00 74.38 ? 43 PHE C CE1 1 ATOM 150 C CE2 . PHE A 1 19 ? -154.113 -146.493 198.965 1.00 68.20 ? 43 PHE C CE2 1 ATOM 151 C CZ . PHE A 1 19 ? -154.948 -145.980 197.991 1.00 71.48 ? 43 PHE C CZ 1 ATOM 152 N N . ALA A 1 20 ? -149.678 -147.255 197.770 1.00 71.99 ? 44 ALA C N 1 ATOM 153 C CA . ALA A 1 20 ? -149.277 -146.031 198.428 1.00 68.79 ? 44 ALA C CA 1 ATOM 154 C C . ALA A 1 20 ? -148.151 -145.321 197.687 1.00 75.00 ? 44 ALA C C 1 ATOM 155 O O . ALA A 1 20 ? -148.138 -144.095 197.603 1.00 74.00 ? 44 ALA C O 1 ATOM 156 C CB . ALA A 1 20 ? -148.866 -146.321 199.838 1.00 70.56 ? 44 ALA C CB 1 ATOM 157 N N . VAL A 1 21 ? -147.195 -146.074 197.158 1.00 71.79 ? 45 VAL C N 1 ATOM 158 C CA . VAL A 1 21 ? -146.124 -145.428 196.416 1.00 72.85 ? 45 VAL C CA 1 ATOM 159 C C . VAL A 1 21 ? -146.546 -145.212 194.974 1.00 73.67 ? 45 VAL C C 1 ATOM 160 O O . VAL A 1 21 ? -146.722 -146.170 194.212 1.00 72.65 ? 45 VAL C O 1 ATOM 161 C CB . VAL A 1 21 ? -144.821 -146.244 196.426 1.00 67.71 ? 45 VAL C CB 1 ATOM 162 C CG1 . VAL A 1 21 ? -143.757 -145.530 195.629 1.00 66.06 ? 45 VAL C CG1 1 ATOM 163 C CG2 . VAL A 1 21 ? -144.350 -146.460 197.816 1.00 68.72 ? 45 VAL C CG2 1 ATOM 164 N N . ASP A 1 22 ? -146.689 -143.949 194.596 1.00 72.05 ? 46 ASP C N 1 ATOM 165 C CA . ASP A 1 22 ? -146.970 -143.609 193.208 1.00 73.32 ? 46 ASP C CA 1 ATOM 166 C C . ASP A 1 22 ? -146.179 -142.385 192.777 1.00 70.62 ? 46 ASP C C 1 ATOM 167 O O . ASP A 1 22 ? -145.139 -142.082 193.358 1.00 72.07 ? 46 ASP C O 1 ATOM 168 C CB . ASP A 1 22 ? -148.462 -143.384 192.988 1.00 70.63 ? 46 ASP C CB 1 ATOM 169 C CG . ASP A 1 22 ? -149.009 -142.233 193.797 1.00 78.46 ? 46 ASP C CG 1 ATOM 170 O OD1 . ASP A 1 22 ? -148.248 -141.553 194.531 1.00 74.28 ? 46 ASP C OD1 1 ATOM 171 O OD2 . ASP A 1 22 ? -150.233 -142.014 193.696 1.00 87.70 ? 46 ASP C OD2 1 ATOM 172 N N . LEU A 1 23 ? -146.681 -141.693 191.760 1.00 69.35 ? 47 LEU C N 1 ATOM 173 C CA . LEU A 1 23 ? -145.949 -140.597 191.141 1.00 68.35 ? 47 LEU C CA 1 ATOM 174 C C . LEU A 1 23 ? -145.699 -139.414 192.065 1.00 70.59 ? 47 LEU C C 1 ATOM 175 O O . LEU A 1 23 ? -144.675 -138.746 191.946 1.00 73.18 ? 47 LEU C O 1 ATOM 176 C CB . LEU A 1 23 ? -146.689 -140.136 189.893 1.00 66.57 ? 47 LEU C CB 1 ATOM 177 C CG . LEU A 1 23 ? -146.559 -141.234 188.852 1.00 66.08 ? 47 LEU C CG 1 ATOM 178 C CD1 . LEU A 1 23 ? -147.842 -141.422 188.095 1.00 72.42 ? 47 LEU C CD1 1 ATOM 179 C CD2 . LEU A 1 23 ? -145.402 -140.926 187.913 1.00 66.97 ? 47 LEU C CD2 1 ATOM 180 N N . ALA A 1 24 ? -146.608 -139.166 193.001 1.00 67.72 ? 48 ALA C N 1 ATOM 181 C CA . ALA A 1 24 ? -146.444 -138.045 193.926 1.00 67.19 ? 48 ALA C CA 1 ATOM 182 C C . ALA A 1 24 ? -145.286 -138.262 194.908 1.00 74.19 ? 48 ALA C C 1 ATOM 183 O O . ALA A 1 24 ? -144.796 -137.310 195.514 1.00 75.40 ? 48 ALA C O 1 ATOM 184 C CB . ALA A 1 24 ? -147.714 -137.796 194.687 1.00 66.70 ? 48 ALA C CB 1 ATOM 185 N N . ASN A 1 25 ? -144.871 -139.514 195.104 1.00 78.80 ? 49 ASN C N 1 ATOM 186 C CA . ASN A 1 25 ? -143.672 -139.790 195.893 1.00 68.84 ? 49 ASN C CA 1 ATOM 187 C C . ASN A 1 25 ? -142.496 -139.164 195.186 1.00 70.76 ? 49 ASN C C 1 ATOM 188 O O . ASN A 1 25 ? -141.544 -138.730 195.829 1.00 73.84 ? 49 ASN C O 1 ATOM 189 C CB . ASN A 1 25 ? -143.440 -141.295 196.078 1.00 64.89 ? 49 ASN C CB 1 ATOM 190 C CG . ASN A 1 25 ? -144.447 -141.948 197.025 1.00 68.20 ? 49 ASN C CG 1 ATOM 191 O OD1 . ASN A 1 25 ? -145.640 -142.044 196.705 1.00 75.86 ? 49 ASN C OD1 1 ATOM 192 N ND2 . ASN A 1 25 ? -143.964 -142.452 198.159 1.00 65.98 ? 49 ASN C ND2 1 ATOM 193 N N . VAL A 1 26 ? -142.577 -139.104 193.854 1.00 68.48 ? 50 VAL C N 1 ATOM 194 C CA . VAL A 1 26 ? -141.485 -138.550 193.063 1.00 69.15 ? 50 VAL C CA 1 ATOM 195 C C . VAL A 1 26 ? -141.685 -137.081 192.745 1.00 67.42 ? 50 VAL C C 1 ATOM 196 O O . VAL A 1 26 ? -140.760 -136.284 192.876 1.00 72.25 ? 50 VAL C O 1 ATOM 197 C CB . VAL A 1 26 ? -141.293 -139.289 191.723 1.00 62.79 ? 50 VAL C CB 1 ATOM 198 C CG1 . VAL A 1 26 ? -140.271 -138.561 190.883 1.00 61.79 ? 50 VAL C CG1 1 ATOM 199 C CG2 . VAL A 1 26 ? -140.864 -140.707 191.945 1.00 54.57 ? 50 VAL C CG2 1 ATOM 200 N N . TRP A 1 27 ? -142.881 -136.709 192.312 1.00 64.85 ? 51 TRP C N 1 ATOM 201 C CA . TRP A 1 27 ? -143.014 -135.378 191.756 1.00 70.64 ? 51 TRP C CA 1 ATOM 202 C C . TRP A 1 27 ? -143.638 -134.350 192.713 1.00 73.39 ? 51 TRP C C 1 ATOM 203 O O . TRP A 1 27 ? -143.913 -133.220 192.294 1.00 73.76 ? 51 TRP C O 1 ATOM 204 C CB . TRP A 1 27 ? -143.771 -135.424 190.409 1.00 66.65 ? 51 TRP C CB 1 ATOM 205 C CG . TRP A 1 27 ? -145.271 -135.680 190.391 1.00 71.50 ? 51 TRP C CG 1 ATOM 206 C CD1 . TRP A 1 27 ? -146.177 -135.470 191.399 1.00 71.71 ? 51 TRP C CD1 1 ATOM 207 C CD2 . TRP A 1 27 ? -146.027 -136.189 189.278 1.00 70.55 ? 51 TRP C CD2 1 ATOM 208 N NE1 . TRP A 1 27 ? -147.446 -135.806 190.974 1.00 68.00 ? 51 TRP C NE1 1 ATOM 209 C CE2 . TRP A 1 27 ? -147.375 -136.258 189.681 1.00 65.24 ? 51 TRP C CE2 1 ATOM 210 C CE3 . TRP A 1 27 ? -145.690 -136.590 187.976 1.00 78.02 ? 51 TRP C CE3 1 ATOM 211 C CZ2 . TRP A 1 27 ? -148.379 -136.714 188.830 1.00 69.34 ? 51 TRP C CZ2 1 ATOM 212 C CZ3 . TRP A 1 27 ? -146.686 -137.034 187.140 1.00 78.27 ? 51 TRP C CZ3 1 ATOM 213 C CH2 . TRP A 1 27 ? -148.012 -137.098 187.568 1.00 74.19 ? 51 TRP C CH2 1 ATOM 214 N N . ARG A 1 28 ? -143.828 -134.704 193.989 1.00 68.13 ? 52 ARG C N 1 ATOM 215 C CA . ARG A 1 28 ? -144.267 -133.704 194.968 1.00 64.74 ? 52 ARG C CA 1 ATOM 216 C C . ARG A 1 28 ? -143.433 -133.673 196.258 1.00 68.99 ? 52 ARG C C 1 ATOM 217 O O . ARG A 1 28 ? -143.053 -132.599 196.716 1.00 72.22 ? 52 ARG C O 1 ATOM 218 C CB . ARG A 1 28 ? -145.744 -133.898 195.319 1.00 66.83 ? 52 ARG C CB 1 ATOM 219 C CG . ARG A 1 28 ? -146.251 -132.883 196.338 1.00 67.52 ? 52 ARG C CG 1 ATOM 220 C CD . ARG A 1 28 ? -147.557 -132.224 195.912 1.00 71.92 ? 52 ARG C CD 1 ATOM 221 N NE . ARG A 1 28 ? -148.043 -131.338 196.972 1.00 87.74 ? 52 ARG C NE 1 ATOM 222 C CZ . ARG A 1 28 ? -147.959 -130.005 196.963 1.00 83.56 ? 52 ARG C CZ 1 ATOM 223 N NH1 . ARG A 1 28 ? -147.423 -129.363 195.927 1.00 76.39 ? 52 ARG C NH1 1 ATOM 224 N NH2 . ARG A 1 28 ? -148.430 -129.314 197.998 1.00 76.50 ? 52 ARG C NH2 1 ATOM 225 N N . PHE A 1 29 ? -143.134 -134.822 196.854 1.00 66.99 ? 53 PHE C N 1 ATOM 226 C CA . PHE A 1 29 ? -142.398 -134.762 198.113 1.00 72.31 ? 53 PHE C CA 1 ATOM 227 C C . PHE A 1 29 ? -141.053 -134.009 198.006 1.00 72.71 ? 53 PHE C C 1 ATOM 228 O O . PHE A 1 29 ? -140.815 -133.091 198.792 1.00 71.48 ? 53 PHE C O 1 ATOM 229 C CB . PHE A 1 29 ? -142.143 -136.156 198.687 1.00 69.27 ? 53 PHE C CB 1 ATOM 230 C CG . PHE A 1 29 ? -141.258 -136.128 199.897 1.00 71.07 ? 53 PHE C CG 1 ATOM 231 C CD1 . PHE A 1 29 ? -141.786 -135.828 201.146 1.00 72.35 ? 53 PHE C CD1 1 ATOM 232 C CD2 . PHE A 1 29 ? -139.895 -136.378 199.791 1.00 69.23 ? 53 PHE C CD2 1 ATOM 233 C CE1 . PHE A 1 29 ? -140.975 -135.777 202.269 1.00 75.79 ? 53 PHE C CE1 1 ATOM 234 C CE2 . PHE A 1 29 ? -139.080 -136.332 200.912 1.00 66.95 ? 53 PHE C CE2 1 ATOM 235 C CZ . PHE A 1 29 ? -139.620 -136.025 202.151 1.00 68.57 ? 53 PHE C CZ 1 ATOM 236 N N . PRO A 1 30 ? -140.181 -134.379 197.035 1.00 70.88 ? 54 PRO C N 1 ATOM 237 C CA . PRO A 1 30 ? -138.909 -133.654 196.898 1.00 66.84 ? 54 PRO C CA 1 ATOM 238 C C . PRO A 1 30 ? -139.113 -132.167 196.616 1.00 74.30 ? 54 PRO C C 1 ATOM 239 O O . PRO A 1 30 ? -138.350 -131.330 197.109 1.00 73.11 ? 54 PRO C O 1 ATOM 240 C CB . PRO A 1 30 ? -138.256 -134.325 195.697 1.00 63.84 ? 54 PRO C CB 1 ATOM 241 C CG . PRO A 1 30 ? -138.793 -135.709 195.709 1.00 68.83 ? 54 PRO C CG 1 ATOM 242 C CD . PRO A 1 30 ? -140.215 -135.584 196.189 1.00 70.47 ? 54 PRO C CD 1 ATOM 243 N N . TYR A 1 31 ? -140.163 -131.836 195.870 1.00 76.03 ? 55 TYR C N 1 ATOM 244 C CA . TYR A 1 31 ? -140.427 -130.436 195.597 1.00 70.11 ? 55 TYR C CA 1 ATOM 245 C C . TYR A 1 31 ? -140.794 -129.716 196.883 1.00 73.84 ? 55 TYR C C 1 ATOM 246 O O . TYR A 1 31 ? -140.338 -128.601 197.122 1.00 78.49 ? 55 TYR C O 1 ATOM 247 C CB . TYR A 1 31 ? -141.541 -130.272 194.579 1.00 70.31 ? 55 TYR C CB 1 ATOM 248 C CG . TYR A 1 31 ? -142.000 -128.848 194.446 1.00 70.21 ? 55 TYR C CG 1 ATOM 249 C CD1 . TYR A 1 31 ? -141.244 -127.919 193.740 1.00 69.95 ? 55 TYR C CD1 1 ATOM 250 C CD2 . TYR A 1 31 ? -143.189 -128.425 195.025 1.00 69.81 ? 55 TYR C CD2 1 ATOM 251 C CE1 . TYR A 1 31 ? -141.661 -126.607 193.625 1.00 72.46 ? 55 TYR C CE1 1 ATOM 252 C CE2 . TYR A 1 31 ? -143.613 -127.116 194.911 1.00 75.18 ? 55 TYR C CE2 1 ATOM 253 C CZ . TYR A 1 31 ? -142.848 -126.210 194.219 1.00 76.22 ? 55 TYR C CZ 1 ATOM 254 O OH . TYR A 1 31 ? -143.279 -124.901 194.122 1.00 80.12 ? 55 TYR C OH 1 ATOM 255 N N . LEU A 1 32 ? -141.595 -130.360 197.727 1.00 72.64 ? 56 LEU C N 1 ATOM 256 C CA . LEU A 1 32 ? -141.979 -129.741 198.994 1.00 73.63 ? 56 LEU C CA 1 ATOM 257 C C . LEU A 1 32 ? -140.784 -129.540 199.914 1.00 72.74 ? 56 LEU C C 1 ATOM 258 O O . LEU A 1 32 ? -140.748 -128.569 200.663 1.00 74.04 ? 56 LEU C O 1 ATOM 259 C CB . LEU A 1 32 ? -143.043 -130.572 199.703 1.00 69.74 ? 56 LEU C CB 1 ATOM 260 C CG . LEU A 1 32 ? -144.417 -130.540 199.054 1.00 70.20 ? 56 LEU C CG 1 ATOM 261 C CD1 . LEU A 1 32 ? -145.330 -131.557 199.716 1.00 72.87 ? 56 LEU C CD1 1 ATOM 262 C CD2 . LEU A 1 32 ? -145.012 -129.141 199.119 1.00 73.08 ? 56 LEU C CD2 1 ATOM 263 N N . CYS A 1 33 ? -139.814 -130.454 199.864 1.00 73.81 ? 57 CYS C N 1 ATOM 264 C CA . CYS A 1 33 ? -138.616 -130.319 200.694 1.00 75.39 ? 57 CYS C CA 1 ATOM 265 C C . CYS A 1 33 ? -137.824 -129.110 200.232 1.00 75.53 ? 57 CYS C C 1 ATOM 266 O O . CYS A 1 33 ? -137.371 -128.300 201.039 1.00 78.13 ? 57 CYS C O 1 ATOM 267 C CB . CYS A 1 33 ? -137.731 -131.566 200.627 1.00 70.23 ? 57 CYS C CB 1 ATOM 268 S SG . CYS A 1 33 ? -138.253 -132.918 201.710 1.00 79.35 ? 57 CYS C SG 1 ATOM 269 N N . TYR A 1 34 ? -137.694 -128.978 198.918 1.00 71.99 ? 58 TYR C N 1 ATOM 270 C CA . TYR A 1 34 ? -136.952 -127.881 198.342 1.00 71.55 ? 58 TYR C CA 1 ATOM 271 C C . TYR A 1 34 ? -137.616 -126.538 198.653 1.00 75.48 ? 58 TYR C C 1 ATOM 272 O O . TYR A 1 34 ? -136.942 -125.540 198.883 1.00 79.45 ? 58 TYR C O 1 ATOM 273 C CB . TYR A 1 34 ? -136.826 -128.093 196.826 1.00 71.67 ? 58 TYR C CB 1 ATOM 274 C CG . TYR A 1 34 ? -136.585 -126.809 196.071 1.00 71.80 ? 58 TYR C CG 1 ATOM 275 C CD1 . TYR A 1 34 ? -135.300 -126.352 195.838 1.00 67.55 ? 58 TYR C CD1 1 ATOM 276 C CD2 . TYR A 1 34 ? -137.651 -126.049 195.609 1.00 66.08 ? 58 TYR C CD2 1 ATOM 277 C CE1 . TYR A 1 34 ? -135.074 -125.170 195.160 1.00 69.23 ? 58 TYR C CE1 1 ATOM 278 C CE2 . TYR A 1 34 ? -137.444 -124.884 194.932 1.00 73.61 ? 58 TYR C CE2 1 ATOM 279 C CZ . TYR A 1 34 ? -136.147 -124.435 194.709 1.00 76.81 ? 58 TYR C CZ 1 ATOM 280 O OH . TYR A 1 34 ? -135.938 -123.250 194.028 1.00 73.74 ? 58 TYR C OH 1 ATOM 281 N N . LYS A 1 35 ? -138.943 -126.529 198.676 1.00 72.58 ? 59 LYS C N 1 ATOM 282 C CA . LYS A 1 35 ? -139.700 -125.299 198.861 1.00 77.68 ? 59 LYS C CA 1 ATOM 283 C C . LYS A 1 35 ? -139.830 -124.867 200.317 1.00 77.25 ? 59 LYS C C 1 ATOM 284 O O . LYS A 1 35 ? -140.078 -123.695 200.600 1.00 79.58 ? 59 LYS C O 1 ATOM 285 C CB . LYS A 1 35 ? -141.102 -125.458 198.254 1.00 77.96 ? 59 LYS C CB 1 ATOM 286 C CG . LYS A 1 35 ? -142.050 -124.317 198.580 1.00 82.85 ? 59 LYS C CG 1 ATOM 287 C CD . LYS A 1 35 ? -143.463 -124.536 198.021 1.00 93.83 ? 59 LYS C CD 1 ATOM 288 C CE . LYS A 1 35 ? -144.355 -125.333 198.986 1.00 95.30 ? 59 LYS C CE 1 ATOM 289 N NZ . LYS A 1 35 ? -145.824 -125.211 198.656 1.00 97.22 ? 59 LYS C NZ 1 ATOM 290 N N . ASN A 1 36 ? -139.642 -125.804 201.239 1.00 79.00 ? 60 ASN C N 1 ATOM 291 C CA . ASN A 1 36 ? -140.005 -125.570 202.635 1.00 80.06 ? 60 ASN C CA 1 ATOM 292 C C . ASN A 1 36 ? -138.898 -125.799 203.649 1.00 79.99 ? 60 ASN C C 1 ATOM 293 O O . ASN A 1 36 ? -139.123 -126.435 204.669 1.00 85.69 ? 60 ASN C O 1 ATOM 294 C CB . ASN A 1 36 ? -141.193 -126.458 203.018 1.00 79.81 ? 60 ASN C CB 1 ATOM 295 C CG . ASN A 1 36 ? -142.475 -126.038 202.341 1.00 81.15 ? 60 ASN C CG 1 ATOM 296 O OD1 . ASN A 1 36 ? -142.759 -124.854 202.210 1.00 83.49 ? 60 ASN C OD1 1 ATOM 297 N ND2 . ASN A 1 36 ? -143.265 -127.009 201.918 1.00 81.53 ? 60 ASN C ND2 1 ATOM 298 N N . GLY A 1 37 ? -137.715 -125.261 203.399 1.00 81.10 ? 61 GLY C N 1 ATOM 299 C CA . GLY A 1 37 ? -136.666 -125.348 204.392 1.00 81.82 ? 61 GLY C CA 1 ATOM 300 C C . GLY A 1 37 ? -135.870 -126.633 204.389 1.00 82.18 ? 61 GLY C C 1 ATOM 301 O O . GLY A 1 37 ? -135.240 -126.968 205.389 1.00 85.58 ? 61 GLY C O 1 ATOM 302 N N . GLY A 1 38 ? -135.903 -127.362 203.280 1.00 80.01 ? 62 GLY C N 1 ATOM 303 C CA . GLY A 1 38 ? -135.051 -128.529 203.129 1.00 76.36 ? 62 GLY C CA 1 ATOM 304 C C . GLY A 1 38 ? -135.347 -129.576 204.177 1.00 81.14 ? 62 GLY C C 1 ATOM 305 O O . GLY A 1 38 ? -136.511 -129.880 204.440 1.00 82.00 ? 62 GLY C O 1 ATOM 306 N N . GLY A 1 39 ? -134.307 -130.103 204.811 1.00 81.88 ? 63 GLY C N 1 ATOM 307 C CA . GLY A 1 39 ? -134.496 -131.170 205.771 1.00 80.10 ? 63 GLY C CA 1 ATOM 308 C C . GLY A 1 39 ? -135.330 -130.697 206.953 1.00 84.38 ? 63 GLY C C 1 ATOM 309 O O . GLY A 1 39 ? -135.868 -131.512 207.705 1.00 86.52 ? 63 GLY C O 1 ATOM 310 N N . ALA A 1 40 ? -135.451 -129.382 207.121 1.00 82.47 ? 64 ALA C N 1 ATOM 311 C CA . ALA A 1 40 ? -136.327 -128.834 208.156 1.00 82.01 ? 64 ALA C CA 1 ATOM 312 C C . ALA A 1 40 ? -137.781 -129.226 207.909 1.00 84.67 ? 64 ALA C C 1 ATOM 313 O O . ALA A 1 40 ? -138.569 -129.352 208.846 1.00 86.40 ? 64 ALA C O 1 ATOM 314 C CB . ALA A 1 40 ? -136.201 -127.317 208.214 1.00 81.28 ? 64 ALA C CB 1 ATOM 315 N N . PHE A 1 41 ? -138.132 -129.424 206.641 1.00 83.34 ? 65 PHE C N 1 ATOM 316 C CA . PHE A 1 41 ? -139.494 -129.801 206.287 1.00 79.49 ? 65 PHE C CA 1 ATOM 317 C C . PHE A 1 41 ? -139.836 -131.156 206.890 1.00 79.21 ? 65 PHE C C 1 ATOM 318 O O . PHE A 1 41 ? -141.001 -131.451 207.165 1.00 77.67 ? 65 PHE C O 1 ATOM 319 C CB . PHE A 1 41 ? -139.672 -129.839 204.767 1.00 76.69 ? 65 PHE C CB 1 ATOM 320 C CG . PHE A 1 41 ? -141.015 -130.345 204.342 1.00 76.96 ? 65 PHE C CG 1 ATOM 321 C CD1 . PHE A 1 41 ? -142.157 -129.620 204.626 1.00 73.56 ? 65 PHE C CD1 1 ATOM 322 C CD2 . PHE A 1 41 ? -141.141 -131.558 203.678 1.00 80.41 ? 65 PHE C CD2 1 ATOM 323 C CE1 . PHE A 1 41 ? -143.404 -130.086 204.256 1.00 72.09 ? 65 PHE C CE1 1 ATOM 324 C CE2 . PHE A 1 41 ? -142.388 -132.037 203.307 1.00 73.87 ? 65 PHE C CE2 1 ATOM 325 C CZ . PHE A 1 41 ? -143.521 -131.292 203.592 1.00 71.79 ? 65 PHE C CZ 1 ATOM 326 N N . LEU A 1 42 ? -138.808 -131.969 207.105 1.00 78.49 ? 66 LEU C N 1 ATOM 327 C CA . LEU A 1 42 ? -138.992 -133.300 207.660 1.00 78.48 ? 66 LEU C CA 1 ATOM 328 C C . LEU A 1 42 ? -139.637 -133.238 209.048 1.00 82.82 ? 66 LEU C C 1 ATOM 329 O O . LEU A 1 42 ? -140.357 -134.162 209.444 1.00 81.48 ? 66 LEU C O 1 ATOM 330 C CB . LEU A 1 42 ? -137.657 -134.039 207.727 1.00 76.09 ? 66 LEU C CB 1 ATOM 331 C CG . LEU A 1 42 ? -137.022 -134.301 206.360 1.00 80.17 ? 66 LEU C CG 1 ATOM 332 C CD1 . LEU A 1 42 ? -135.568 -134.678 206.503 1.00 79.91 ? 66 LEU C CD1 1 ATOM 333 C CD2 . LEU A 1 42 ? -137.771 -135.382 205.625 1.00 77.60 ? 66 LEU C CD2 1 ATOM 334 N N . VAL A 1 43 ? -139.402 -132.159 209.788 1.00 81.30 ? 67 VAL C N 1 ATOM 335 C CA . VAL A 1 43 ? -139.993 -132.063 211.113 1.00 80.63 ? 67 VAL C CA 1 ATOM 336 C C . VAL A 1 43 ? -141.529 -131.994 211.051 1.00 77.93 ? 67 VAL C C 1 ATOM 337 O O . VAL A 1 43 ? -142.202 -132.864 211.607 1.00 77.82 ? 67 VAL C O 1 ATOM 338 C CB . VAL A 1 43 ? -139.448 -130.840 211.886 1.00 83.32 ? 67 VAL C CB 1 ATOM 339 C CG1 . VAL A 1 43 ? -140.301 -130.580 213.114 1.00 76.78 ? 67 VAL C CG1 1 ATOM 340 C CG2 . VAL A 1 43 ? -137.989 -131.086 212.270 1.00 75.42 ? 67 VAL C CG2 1 ATOM 341 N N . PRO A 1 44 ? -142.093 -130.961 210.399 1.00 81.06 ? 68 PRO C N 1 ATOM 342 C CA . PRO A 1 44 ? -143.554 -130.903 210.251 1.00 79.37 ? 68 PRO C CA 1 ATOM 343 C C . PRO A 1 44 ? -144.101 -132.130 209.542 1.00 80.56 ? 68 PRO C C 1 ATOM 344 O O . PRO A 1 44 ? -145.182 -132.623 209.890 1.00 78.94 ? 68 PRO C O 1 ATOM 345 C CB . PRO A 1 44 ? -143.793 -129.639 209.422 1.00 73.07 ? 68 PRO C CB 1 ATOM 346 C CG . PRO A 1 44 ? -142.485 -129.331 208.785 1.00 77.85 ? 68 PRO C CG 1 ATOM 347 C CD . PRO A 1 44 ? -141.433 -129.818 209.739 1.00 80.50 ? 68 PRO C CD 1 ATOM 348 N N . TYR A 1 45 ? -143.336 -132.641 208.579 1.00 77.85 ? 69 TYR C N 1 ATOM 349 C CA . TYR A 1 45 ? -143.729 -133.827 207.829 1.00 73.11 ? 69 TYR C CA 1 ATOM 350 C C . TYR A 1 45 ? -143.814 -135.047 208.740 1.00 77.87 ? 69 TYR C C 1 ATOM 351 O O . TYR A 1 45 ? -144.791 -135.794 208.700 1.00 77.30 ? 69 TYR C O 1 ATOM 352 C CB . TYR A 1 45 ? -142.730 -134.075 206.706 1.00 75.03 ? 69 TYR C CB 1 ATOM 353 C CG . TYR A 1 45 ? -142.953 -135.353 205.924 1.00 77.06 ? 69 TYR C CG 1 ATOM 354 C CD1 . TYR A 1 45 ? -143.836 -135.391 204.859 1.00 74.49 ? 69 TYR C CD1 1 ATOM 355 C CD2 . TYR A 1 45 ? -142.251 -136.506 206.229 1.00 74.80 ? 69 TYR C CD2 1 ATOM 356 C CE1 . TYR A 1 45 ? -144.027 -136.535 204.132 1.00 74.97 ? 69 TYR C CE1 1 ATOM 357 C CE2 . TYR A 1 45 ? -142.435 -137.661 205.505 1.00 77.13 ? 69 TYR C CE2 1 ATOM 358 C CZ . TYR A 1 45 ? -143.327 -137.670 204.456 1.00 74.61 ? 69 TYR C CZ 1 ATOM 359 O OH . TYR A 1 45 ? -143.534 -138.819 203.724 1.00 71.22 ? 69 TYR C OH 1 ATOM 360 N N . GLY A 1 46 ? -142.802 -135.230 209.583 1.00 78.34 ? 70 GLY C N 1 ATOM 361 C CA . GLY A 1 46 ? -142.761 -136.383 210.460 1.00 73.90 ? 70 GLY C CA 1 ATOM 362 C C . GLY A 1 46 ? -143.817 -136.327 211.545 1.00 75.89 ? 70 GLY C C 1 ATOM 363 O O . GLY A 1 46 ? -144.411 -137.342 211.904 1.00 83.76 ? 70 GLY C O 1 ATOM 364 N N . ILE A 1 47 ? -144.074 -135.138 212.067 1.00 73.62 ? 71 ILE C N 1 ATOM 365 C CA . ILE A 1 47 ? -145.104 -134.998 213.079 1.00 76.14 ? 71 ILE C CA 1 ATOM 366 C C . ILE A 1 47 ? -146.490 -135.258 212.478 1.00 78.28 ? 71 ILE C C 1 ATOM 367 O O . ILE A 1 47 ? -147.304 -135.958 213.083 1.00 80.18 ? 71 ILE C O 1 ATOM 368 C CB . ILE A 1 47 ? -145.051 -133.606 213.721 1.00 76.93 ? 71 ILE C CB 1 ATOM 369 C CG1 . ILE A 1 47 ? -143.748 -133.441 214.494 1.00 68.56 ? 71 ILE C CG1 1 ATOM 370 C CG2 . ILE A 1 47 ? -146.226 -133.391 214.632 1.00 69.70 ? 71 ILE C CG2 1 ATOM 371 C CD1 . ILE A 1 47 ? -143.298 -132.015 214.588 1.00 69.42 ? 71 ILE C CD1 1 ATOM 372 N N . MET A 1 48 ? -146.747 -134.733 211.278 1.00 77.23 ? 72 MET C N 1 ATOM 373 C CA . MET A 1 48 ? -148.027 -135.000 210.604 1.00 81.67 ? 72 MET C CA 1 ATOM 374 C C . MET A 1 48 ? -148.173 -136.485 210.266 1.00 80.70 ? 72 MET C C 1 ATOM 375 O O . MET A 1 48 ? -149.264 -137.061 210.284 1.00 77.33 ? 72 MET C O 1 ATOM 376 C CB . MET A 1 48 ? -148.162 -134.186 209.320 1.00 77.00 ? 72 MET C CB 1 ATOM 377 C CG . MET A 1 48 ? -148.413 -132.701 209.519 1.00 82.23 ? 72 MET C CG 1 ATOM 378 S SD . MET A 1 48 ? -149.643 -132.301 210.775 1.00 80.56 ? 72 MET C SD 1 ATOM 379 C CE . MET A 1 48 ? -148.582 -132.240 212.225 1.00 84.02 ? 72 MET C CE 1 ATOM 380 N N . LEU A 1 49 ? -147.050 -137.102 209.940 1.00 78.02 ? 73 LEU C N 1 ATOM 381 C CA . LEU A 1 49 ? -147.048 -138.510 209.607 1.00 75.57 ? 73 LEU C CA 1 ATOM 382 C C . LEU A 1 49 ? -147.438 -139.327 210.835 1.00 81.10 ? 73 LEU C C 1 ATOM 383 O O . LEU A 1 49 ? -148.159 -140.334 210.738 1.00 77.64 ? 73 LEU C O 1 ATOM 384 C CB . LEU A 1 49 ? -145.673 -138.907 209.109 1.00 74.25 ? 73 LEU C CB 1 ATOM 385 C CG . LEU A 1 49 ? -145.520 -140.281 208.505 1.00 78.13 ? 73 LEU C CG 1 ATOM 386 C CD1 . LEU A 1 49 ? -146.701 -140.559 207.603 1.00 73.17 ? 73 LEU C CD1 1 ATOM 387 C CD2 . LEU A 1 49 ? -144.224 -140.322 207.722 1.00 81.01 ? 73 LEU C CD2 1 ATOM 388 N N . ALA A 1 50 ? -146.994 -138.851 211.998 1.00 80.58 ? 74 ALA C N 1 ATOM 389 C CA . ALA A 1 50 ? -147.097 -139.611 213.231 1.00 75.63 ? 74 ALA C CA 1 ATOM 390 C C . ALA A 1 50 ? -148.460 -139.485 213.897 1.00 81.64 ? 74 ALA C C 1 ATOM 391 O O . ALA A 1 50 ? -148.982 -140.460 214.448 1.00 83.01 ? 74 ALA C O 1 ATOM 392 C CB . ALA A 1 50 ? -146.014 -139.175 214.182 1.00 77.76 ? 74 ALA C CB 1 ATOM 393 N N . VAL A 1 51 ? -149.025 -138.281 213.864 1.00 79.55 ? 75 VAL C N 1 ATOM 394 C CA . VAL A 1 51 ? -150.280 -138.005 214.566 1.00 79.37 ? 75 VAL C CA 1 ATOM 395 C C . VAL A 1 51 ? -151.500 -138.005 213.634 1.00 81.75 ? 75 VAL C C 1 ATOM 396 O O . VAL A 1 51 ? -152.648 -138.122 214.075 1.00 84.87 ? 75 VAL C O 1 ATOM 397 C CB . VAL A 1 51 ? -150.199 -136.658 215.293 1.00 77.44 ? 75 VAL C CB 1 ATOM 398 C CG1 . VAL A 1 51 ? -148.879 -136.562 216.059 1.00 77.31 ? 75 VAL C CG1 1 ATOM 399 C CG2 . VAL A 1 51 ? -150.296 -135.527 214.298 1.00 73.13 ? 75 VAL C CG2 1 ATOM 400 N N . GLY A 1 52 ? -151.256 -137.873 212.337 1.00 79.35 ? 76 GLY C N 1 ATOM 401 C CA . GLY A 1 52 ? -152.348 -137.814 211.389 1.00 73.17 ? 76 GLY C CA 1 ATOM 402 C C . GLY A 1 52 ? -152.352 -138.994 210.448 1.00 77.07 ? 76 GLY C C 1 ATOM 403 O O . GLY A 1 52 ? -153.249 -139.845 210.493 1.00 81.38 ? 76 GLY C O 1 ATOM 404 N N . GLY A 1 53 ? -151.333 -139.056 209.603 1.00 78.13 ? 77 GLY C N 1 ATOM 405 C CA . GLY A 1 53 ? -151.303 -140.025 208.534 1.00 74.08 ? 77 GLY C CA 1 ATOM 406 C C . GLY A 1 53 ? -151.306 -141.449 209.025 1.00 74.24 ? 77 GLY C C 1 ATOM 407 O O . GLY A 1 53 ? -152.250 -142.193 208.782 1.00 73.72 ? 77 GLY C O 1 ATOM 408 N N . ILE A 1 54 ? -150.249 -141.841 209.725 1.00 77.90 ? 78 ILE C N 1 ATOM 409 C CA . ILE A 1 54 ? -150.118 -143.248 210.101 1.00 75.84 ? 78 ILE C CA 1 ATOM 410 C C . ILE A 1 54 ? -151.298 -143.738 210.952 1.00 74.94 ? 78 ILE C C 1 ATOM 411 O O . ILE A 1 54 ? -151.824 -144.827 210.703 1.00 77.40 ? 78 ILE C O 1 ATOM 412 C CB . ILE A 1 54 ? -148.819 -143.517 210.818 1.00 70.22 ? 78 ILE C CB 1 ATOM 413 C CG1 . ILE A 1 54 ? -147.645 -143.230 209.889 1.00 74.42 ? 78 ILE C CG1 1 ATOM 414 C CG2 . ILE A 1 54 ? -148.740 -144.952 211.212 1.00 70.93 ? 78 ILE C CG2 1 ATOM 415 C CD1 . ILE A 1 54 ? -146.316 -143.652 210.431 1.00 77.20 ? 78 ILE C CD1 1 ATOM 416 N N . PRO A 1 55 ? -151.716 -142.963 211.956 1.00 73.88 ? 79 PRO C N 1 ATOM 417 C CA . PRO A 1 55 ? -152.896 -143.440 212.678 1.00 77.13 ? 79 PRO C CA 1 ATOM 418 C C . PRO A 1 55 ? -154.122 -143.679 211.793 1.00 77.14 ? 79 PRO C C 1 ATOM 419 O O . PRO A 1 55 ? -154.816 -144.673 211.996 1.00 78.02 ? 79 PRO C O 1 ATOM 420 C CB . PRO A 1 55 ? -153.172 -142.314 213.668 1.00 74.82 ? 79 PRO C CB 1 ATOM 421 C CG . PRO A 1 55 ? -151.828 -141.680 213.893 1.00 74.43 ? 79 PRO C CG 1 ATOM 422 C CD . PRO A 1 55 ? -151.140 -141.753 212.557 1.00 74.70 ? 79 PRO C CD 1 ATOM 423 N N . LEU A 1 56 ? -154.381 -142.816 210.817 1.00 74.77 ? 80 LEU C N 1 ATOM 424 C CA . LEU A 1 56 ? -155.526 -143.040 209.930 1.00 72.26 ? 80 LEU C CA 1 ATOM 425 C C . LEU A 1 56 ? -155.265 -144.252 209.070 1.00 74.14 ? 80 LEU C C 1 ATOM 426 O O . LEU A 1 56 ? -156.184 -144.986 208.697 1.00 74.48 ? 80 LEU C O 1 ATOM 427 C CB . LEU A 1 56 ? -155.791 -141.816 209.052 1.00 73.30 ? 80 LEU C CB 1 ATOM 428 C CG . LEU A 1 56 ? -156.467 -140.612 209.715 1.00 72.78 ? 80 LEU C CG 1 ATOM 429 C CD1 . LEU A 1 56 ? -156.535 -139.473 208.753 1.00 77.46 ? 80 LEU C CD1 1 ATOM 430 C CD2 . LEU A 1 56 ? -157.868 -140.992 210.164 1.00 79.17 ? 80 LEU C CD2 1 ATOM 431 N N . PHE A 1 57 ? -153.986 -144.442 208.759 1.00 75.75 ? 81 PHE C N 1 ATOM 432 C CA . PHE A 1 57 ? -153.531 -145.492 207.855 1.00 73.93 ? 81 PHE C CA 1 ATOM 433 C C . PHE A 1 57 ? -153.689 -146.842 208.535 1.00 76.87 ? 81 PHE C C 1 ATOM 434 O O . PHE A 1 57 ? -154.218 -147.798 207.955 1.00 76.37 ? 81 PHE C O 1 ATOM 435 C CB . PHE A 1 57 ? -152.077 -145.229 207.471 1.00 73.79 ? 81 PHE C CB 1 ATOM 436 C CG . PHE A 1 57 ? -151.494 -146.223 206.518 1.00 69.54 ? 81 PHE C CG 1 ATOM 437 C CD1 . PHE A 1 57 ? -151.789 -146.161 205.174 1.00 71.23 ? 81 PHE C CD1 1 ATOM 438 C CD2 . PHE A 1 57 ? -150.616 -147.198 206.965 1.00 69.45 ? 81 PHE C CD2 1 ATOM 439 C CE1 . PHE A 1 57 ? -151.232 -147.070 204.282 1.00 69.38 ? 81 PHE C CE1 1 ATOM 440 C CE2 . PHE A 1 57 ? -150.061 -148.105 206.084 1.00 71.83 ? 81 PHE C CE2 1 ATOM 441 C CZ . PHE A 1 57 ? -150.381 -148.036 204.734 1.00 68.62 ? 81 PHE C CZ 1 ATOM 442 N N . TYR A 1 58 ? -153.252 -146.885 209.793 1.00 77.56 ? 82 TYR C N 1 ATOM 443 C CA . TYR A 1 58 ? -153.411 -148.034 210.674 1.00 71.41 ? 82 TYR C CA 1 ATOM 444 C C . TYR A 1 58 ? -154.886 -148.403 210.808 1.00 76.51 ? 82 TYR C C 1 ATOM 445 O O . TYR A 1 58 ? -155.278 -149.565 210.646 1.00 75.92 ? 82 TYR C O 1 ATOM 446 C CB . TYR A 1 58 ? -152.817 -147.678 212.024 1.00 73.89 ? 82 TYR C CB 1 ATOM 447 C CG . TYR A 1 58 ? -152.888 -148.711 213.122 1.00 81.20 ? 82 TYR C CG 1 ATOM 448 C CD1 . TYR A 1 58 ? -153.123 -150.058 212.857 1.00 80.35 ? 82 TYR C CD1 1 ATOM 449 C CD2 . TYR A 1 58 ? -152.702 -148.326 214.449 1.00 84.06 ? 82 TYR C CD2 1 ATOM 450 C CE1 . TYR A 1 58 ? -153.171 -150.988 213.894 1.00 79.63 ? 82 TYR C CE1 1 ATOM 451 C CE2 . TYR A 1 58 ? -152.751 -149.242 215.478 1.00 86.00 ? 82 TYR C CE2 1 ATOM 452 C CZ . TYR A 1 58 ? -152.986 -150.565 215.202 1.00 82.59 ? 82 TYR C CZ 1 ATOM 453 O OH . TYR A 1 58 ? -153.026 -151.449 216.254 1.00 81.14 ? 82 TYR C OH 1 ATOM 454 N N . MET A 1 59 ? -155.707 -147.387 211.055 1.00 78.21 ? 83 MET C N 1 ATOM 455 C CA . MET A 1 59 ? -157.108 -147.600 211.366 1.00 75.48 ? 83 MET C CA 1 ATOM 456 C C . MET A 1 59 ? -157.819 -148.317 210.244 1.00 77.11 ? 83 MET C C 1 ATOM 457 O O . MET A 1 59 ? -158.458 -149.347 210.472 1.00 79.72 ? 83 MET C O 1 ATOM 458 C CB . MET A 1 59 ? -157.798 -146.270 211.641 1.00 78.75 ? 83 MET C CB 1 ATOM 459 C CG . MET A 1 59 ? -159.300 -146.359 211.895 1.00 79.12 ? 83 MET C CG 1 ATOM 460 S SD . MET A 1 59 ? -159.982 -144.728 212.268 1.00 88.97 ? 83 MET C SD 1 ATOM 461 C CE . MET A 1 59 ? -160.293 -144.136 210.597 1.00 86.38 ? 83 MET C CE 1 ATOM 462 N N . GLU A 1 60 ? -157.702 -147.793 209.029 1.00 77.44 ? 84 GLU C N 1 ATOM 463 C CA . GLU A 1 60 ? -158.462 -148.367 207.935 1.00 79.66 ? 84 GLU C CA 1 ATOM 464 C C . GLU A 1 60 ? -157.982 -149.790 207.673 1.00 78.40 ? 84 GLU C C 1 ATOM 465 O O . GLU A 1 60 ? -158.791 -150.672 207.369 1.00 78.47 ? 84 GLU C O 1 ATOM 466 C CB . GLU A 1 60 ? -158.351 -147.513 206.669 1.00 79.77 ? 84 GLU C CB 1 ATOM 467 C CG . GLU A 1 60 ? -159.299 -147.955 205.558 1.00 83.07 ? 84 GLU C CG 1 ATOM 468 C CD . GLU A 1 60 ? -159.014 -147.282 204.220 1.00 86.67 ? 84 GLU C CD 1 ATOM 469 O OE1 . GLU A 1 60 ? -158.156 -146.376 204.176 1.00 84.98 ? 84 GLU C OE1 1 ATOM 470 O OE2 . GLU A 1 60 ? -159.649 -147.661 203.208 1.00 89.79 ? 84 GLU C OE2 1 ATOM 471 N N . LEU A 1 61 ? -156.677 -150.024 207.833 1.00 75.38 ? 85 LEU C N 1 ATOM 472 C CA . LEU A 1 61 ? -156.140 -151.366 207.619 1.00 74.74 ? 85 LEU C CA 1 ATOM 473 C C . LEU A 1 61 ? -156.686 -152.355 208.650 1.00 74.44 ? 85 LEU C C 1 ATOM 474 O O . LEU A 1 61 ? -157.096 -153.459 208.299 1.00 72.52 ? 85 LEU C O 1 ATOM 475 C CB . LEU A 1 61 ? -154.611 -151.358 207.665 1.00 71.52 ? 85 LEU C CB 1 ATOM 476 C CG . LEU A 1 61 ? -153.853 -150.949 206.404 1.00 72.13 ? 85 LEU C CG 1 ATOM 477 C CD1 . LEU A 1 61 ? -152.373 -150.826 206.704 1.00 69.74 ? 85 LEU C CD1 1 ATOM 478 C CD2 . LEU A 1 61 ? -154.072 -151.940 205.280 1.00 71.20 ? 85 LEU C CD2 1 ATOM 479 N N . ALA A 1 62 ? -156.725 -151.952 209.916 1.00 73.54 ? 86 ALA C N 1 ATOM 480 C CA . ALA A 1 62 ? -157.237 -152.839 210.952 1.00 73.95 ? 86 ALA C CA 1 ATOM 481 C C . ALA A 1 62 ? -158.700 -153.102 210.699 1.00 75.38 ? 86 ALA C C 1 ATOM 482 O O . ALA A 1 62 ? -159.180 -154.234 210.779 1.00 80.02 ? 86 ALA C O 1 ATOM 483 C CB . ALA A 1 62 ? -157.039 -152.228 212.339 1.00 73.39 ? 86 ALA C CB 1 ATOM 484 N N . LEU A 1 63 ? -159.397 -152.034 210.351 1.00 80.10 ? 87 LEU C N 1 ATOM 485 C CA . LEU A 1 63 ? -160.828 -152.087 210.176 1.00 78.90 ? 87 LEU C CA 1 ATOM 486 C C . LEU A 1 63 ? -161.200 -153.014 209.021 1.00 80.11 ? 87 LEU C C 1 ATOM 487 O O . LEU A 1 63 ? -162.191 -153.734 209.085 1.00 80.86 ? 87 LEU C O 1 ATOM 488 C CB . LEU A 1 63 ? -161.353 -150.678 209.937 1.00 77.60 ? 87 LEU C CB 1 ATOM 489 C CG . LEU A 1 63 ? -162.843 -150.513 210.154 1.00 86.43 ? 87 LEU C CG 1 ATOM 490 C CD1 . LEU A 1 63 ? -163.188 -150.879 211.584 1.00 89.76 ? 87 LEU C CD1 1 ATOM 491 C CD2 . LEU A 1 63 ? -163.241 -149.081 209.841 1.00 91.43 ? 87 LEU C CD2 1 ATOM 492 N N . GLY A 1 64 ? -160.395 -153.012 207.967 1.00 75.89 ? 88 GLY C N 1 ATOM 493 C CA . GLY A 1 64 ? -160.691 -153.872 206.843 1.00 76.16 ? 88 GLY C CA 1 ATOM 494 C C . GLY A 1 64 ? -160.415 -155.328 207.165 1.00 81.18 ? 88 GLY C C 1 ATOM 495 O O . GLY A 1 64 ? -161.151 -156.215 206.739 1.00 83.81 ? 88 GLY C O 1 ATOM 496 N N . GLN A 1 65 ? -159.358 -155.579 207.931 1.00 81.29 ? 89 GLN C N 1 ATOM 497 C CA . GLN A 1 65 ? -159.035 -156.943 208.325 1.00 80.23 ? 89 GLN C CA 1 ATOM 498 C C . GLN A 1 65 ? -160.067 -157.522 209.298 1.00 82.96 ? 89 GLN C C 1 ATOM 499 O O . GLN A 1 65 ? -160.394 -158.713 209.241 1.00 79.29 ? 89 GLN C O 1 ATOM 500 C CB . GLN A 1 65 ? -157.645 -157.005 208.950 1.00 74.67 ? 89 GLN C CB 1 ATOM 501 C CG . GLN A 1 65 ? -157.250 -158.403 209.399 1.00 74.99 ? 89 GLN C CG 1 ATOM 502 C CD . GLN A 1 65 ? -155.820 -158.479 209.885 1.00 74.64 ? 89 GLN C CD 1 ATOM 503 O OE1 . GLN A 1 65 ? -154.876 -158.133 209.164 1.00 75.28 ? 89 GLN C OE1 1 ATOM 504 N NE2 . GLN A 1 65 ? -155.648 -158.927 211.119 1.00 74.98 ? 89 GLN C NE2 1 ATOM 505 N N . HIS A 1 66 ? -160.599 -156.678 210.176 1.00 80.08 ? 90 HIS C N 1 ATOM 506 C CA . HIS A 1 66 ? -161.547 -157.158 211.161 1.00 81.06 ? 90 HIS C CA 1 ATOM 507 C C . HIS A 1 66 ? -162.928 -157.449 210.566 1.00 85.43 ? 90 HIS C C 1 ATOM 508 O O . HIS A 1 66 ? -163.500 -158.515 210.791 1.00 87.75 ? 90 HIS C O 1 ATOM 509 C CB . HIS A 1 66 ? -161.684 -156.151 212.283 1.00 80.31 ? 90 HIS C CB 1 ATOM 510 C CG . HIS A 1 66 ? -162.626 -156.586 213.366 1.00 86.66 ? 90 HIS C CG 1 ATOM 511 N ND1 . HIS A 1 66 ? -163.580 -155.752 213.904 1.00 93.64 ? 90 HIS C ND1 1 ATOM 512 C CD2 . HIS A 1 66 ? -162.739 -157.766 214.022 1.00 86.31 ? 90 HIS C CD2 1 ATOM 513 C CE1 . HIS A 1 66 ? -164.254 -156.404 214.839 1.00 90.80 ? 90 HIS C CE1 1 ATOM 514 N NE2 . HIS A 1 66 ? -163.763 -157.625 214.929 1.00 88.32 ? 90 HIS C NE2 1 ATOM 515 N N . ASN A 1 67 ? -163.458 -156.502 209.801 1.00 84.03 ? 91 ASN C N 1 ATOM 516 C CA . ASN A 1 67 ? -164.816 -156.621 209.292 1.00 78.12 ? 91 ASN C CA 1 ATOM 517 C C . ASN A 1 67 ? -164.898 -157.440 208.008 1.00 83.91 ? 91 ASN C C 1 ATOM 518 O O . ASN A 1 67 ? -165.977 -157.816 207.566 1.00 88.85 ? 91 ASN C O 1 ATOM 519 C CB . ASN A 1 67 ? -165.407 -155.232 209.103 1.00 76.44 ? 91 ASN C CB 1 ATOM 520 C CG . ASN A 1 67 ? -165.622 -154.520 210.433 1.00 88.47 ? 91 ASN C CG 1 ATOM 521 O OD1 . ASN A 1 67 ? -166.071 -155.131 211.407 1.00 93.65 ? 91 ASN C OD1 1 ATOM 522 N ND2 . ASN A 1 67 ? -165.273 -153.238 210.493 1.00 94.65 ? 91 ASN C ND2 1 ATOM 523 N N . ARG A 1 68 ? -163.744 -157.720 207.418 1.00 87.60 ? 92 ARG C N 1 ATOM 524 C CA . ARG A 1 68 ? -163.627 -158.691 206.332 1.00 89.10 ? 92 ARG C CA 1 ATOM 525 C C . ARG A 1 68 ? -164.575 -158.449 205.152 1.00 88.82 ? 92 ARG C C 1 ATOM 526 O O . ARG A 1 68 ? -164.927 -159.383 204.433 1.00 91.22 ? 92 ARG C O 1 ATOM 527 C CB . ARG A 1 68 ? -163.834 -160.094 206.907 1.00 84.91 ? 92 ARG C CB 1 ATOM 528 C CG . ARG A 1 68 ? -162.827 -160.410 207.998 1.00 87.48 ? 92 ARG C CG 1 ATOM 529 C CD . ARG A 1 68 ? -163.148 -161.687 208.769 1.00 99.33 ? 92 ARG C CD 1 ATOM 530 N NE . ARG A 1 68 ? -163.056 -162.904 207.958 1.00 110.25 ? 92 ARG C NE 1 ATOM 531 C CZ . ARG A 1 68 ? -161.975 -163.285 207.277 1.00 107.61 ? 92 ARG C CZ 1 ATOM 532 N NH1 . ARG A 1 68 ? -162.016 -164.414 206.570 1.00 103.30 ? 92 ARG C NH1 1 ATOM 533 N NH2 . ARG A 1 68 ? -160.863 -162.535 207.293 1.00 95.23 ? 92 ARG C NH2 1 ATOM 534 N N . LYS A 1 69 ? -164.948 -157.189 204.932 1.00 89.37 ? 93 LYS C N 1 ATOM 535 C CA . LYS A 1 69 ? -165.791 -156.815 203.794 1.00 89.43 ? 93 LYS C CA 1 ATOM 536 C C . LYS A 1 69 ? -165.254 -155.549 203.151 1.00 87.55 ? 93 LYS C C 1 ATOM 537 O O . LYS A 1 69 ? -164.442 -154.841 203.743 1.00 91.91 ? 93 LYS C O 1 ATOM 538 C CB . LYS A 1 69 ? -167.251 -156.597 204.213 1.00 88.67 ? 93 LYS C CB 1 ATOM 539 C CG . LYS A 1 69 ? -167.876 -157.757 204.974 1.00 93.60 ? 93 LYS C CG 1 ATOM 540 C CD . LYS A 1 69 ? -167.904 -159.037 204.150 1.00 90.32 ? 93 LYS C CD 1 ATOM 541 C CE . LYS A 1 69 ? -169.281 -159.293 203.575 1.00 91.18 ? 93 LYS C CE 1 ATOM 542 N NZ . LYS A 1 69 ? -169.359 -160.626 202.912 1.00 95.97 ? 93 LYS C NZ 1 ATOM 543 N N . GLY A 1 70 ? -165.730 -155.258 201.946 1.00 88.21 ? 94 GLY C N 1 ATOM 544 C CA . GLY A 1 70 ? -165.314 -154.074 201.218 1.00 84.85 ? 94 GLY C CA 1 ATOM 545 C C . GLY A 1 70 ? -166.023 -152.850 201.759 1.00 84.70 ? 94 GLY C C 1 ATOM 546 O O . GLY A 1 70 ? -166.800 -152.945 202.702 1.00 85.89 ? 94 GLY C O 1 ATOM 547 N N . ALA A 1 71 ? -165.759 -151.698 201.162 1.00 82.64 ? 95 ALA C N 1 ATOM 548 C CA . ALA A 1 71 ? -166.087 -150.439 201.807 1.00 85.33 ? 95 ALA C CA 1 ATOM 549 C C . ALA A 1 71 ? -167.576 -150.224 202.086 1.00 85.94 ? 95 ALA C C 1 ATOM 550 O O . ALA A 1 71 ? -167.937 -149.676 203.135 1.00 85.44 ? 95 ALA C O 1 ATOM 551 C CB . ALA A 1 71 ? -165.552 -149.288 200.969 1.00 87.33 ? 95 ALA C CB 1 ATOM 552 N N . ILE A 1 72 ? -168.443 -150.660 201.177 1.00 85.54 ? 96 ILE C N 1 ATOM 553 C CA . ILE A 1 72 ? -169.870 -150.384 201.358 1.00 90.29 ? 96 ILE C CA 1 ATOM 554 C C . ILE A 1 72 ? -170.436 -151.200 202.507 1.00 90.50 ? 96 ILE C C 1 ATOM 555 O O . ILE A 1 72 ? -170.999 -150.655 203.452 1.00 88.62 ? 96 ILE C O 1 ATOM 556 C CB . ILE A 1 72 ? -170.691 -150.700 200.104 1.00 89.89 ? 96 ILE C CB 1 ATOM 557 C CG1 . ILE A 1 72 ? -170.212 -149.870 198.921 1.00 85.27 ? 96 ILE C CG1 1 ATOM 558 C CG2 . ILE A 1 72 ? -172.165 -150.461 200.376 1.00 87.62 ? 96 ILE C CG2 1 ATOM 559 C CD1 . ILE A 1 72 ? -170.765 -150.349 197.604 1.00 85.17 ? 96 ILE C CD1 1 ATOM 560 N N . THR A 1 73 ? -170.235 -152.511 202.429 1.00 90.85 ? 97 THR C N 1 ATOM 561 C CA . THR A 1 73 ? -170.728 -153.423 203.440 1.00 85.23 ? 97 THR C CA 1 ATOM 562 C C . THR A 1 73 ? -170.120 -153.113 204.797 1.00 86.07 ? 97 THR C C 1 ATOM 563 O O . THR A 1 73 ? -170.791 -153.170 205.821 1.00 88.03 ? 97 THR C O 1 ATOM 564 C CB . THR A 1 73 ? -170.387 -154.880 203.088 1.00 88.29 ? 97 THR C CB 1 ATOM 565 O OG1 . THR A 1 73 ? -171.083 -155.286 201.899 1.00 92.06 ? 97 THR C OG1 1 ATOM 566 C CG2 . THR A 1 73 ? -170.757 -155.789 204.231 1.00 89.08 ? 97 THR C CG2 1 ATOM 567 N N . CYS A 1 74 ? -168.847 -152.745 204.789 1.00 87.48 ? 98 CYS C N 1 ATOM 568 C CA . CYS A 1 74 ? -168.106 -152.590 206.025 1.00 86.25 ? 98 CYS C CA 1 ATOM 569 C C . CYS A 1 74 ? -168.635 -151.430 206.847 1.00 83.92 ? 98 CYS C C 1 ATOM 570 O O . CYS A 1 74 ? -168.905 -151.572 208.031 1.00 89.32 ? 98 CYS C O 1 ATOM 571 C CB . CYS A 1 74 ? -166.615 -152.394 205.719 1.00 87.36 ? 98 CYS C CB 1 ATOM 572 S SG . CYS A 1 74 ? -165.635 -151.836 207.139 1.00 90.61 ? 98 CYS C SG 1 ATOM 573 N N . TRP A 1 75 ? -168.796 -150.280 206.216 1.00 85.80 ? 99 TRP C N 1 ATOM 574 C CA . TRP A 1 75 ? -169.270 -149.121 206.949 1.00 87.56 ? 99 TRP C CA 1 ATOM 575 C C . TRP A 1 75 ? -170.723 -149.305 207.322 1.00 87.85 ? 99 TRP C C 1 ATOM 576 O O . TRP A 1 75 ? -171.177 -148.765 208.325 1.00 87.99 ? 99 TRP C O 1 ATOM 577 C CB . TRP A 1 75 ? -169.057 -147.843 206.135 1.00 88.24 ? 99 TRP C CB 1 ATOM 578 C CG . TRP A 1 75 ? -167.624 -147.446 206.139 1.00 82.56 ? 99 TRP C CG 1 ATOM 579 C CD1 . TRP A 1 75 ? -166.746 -147.534 205.106 1.00 85.70 ? 99 TRP C CD1 1 ATOM 580 C CD2 . TRP A 1 75 ? -166.889 -146.935 207.251 1.00 74.09 ? 99 TRP C CD2 1 ATOM 581 N NE1 . TRP A 1 75 ? -165.508 -147.092 205.502 1.00 89.57 ? 99 TRP C NE1 1 ATOM 582 C CE2 . TRP A 1 75 ? -165.574 -146.718 206.817 1.00 82.51 ? 99 TRP C CE2 1 ATOM 583 C CE3 . TRP A 1 75 ? -167.222 -146.627 208.568 1.00 80.86 ? 99 TRP C CE3 1 ATOM 584 C CZ2 . TRP A 1 75 ? -164.588 -146.211 207.659 1.00 87.51 ? 99 TRP C CZ2 1 ATOM 585 C CZ3 . TRP A 1 75 ? -166.245 -146.118 209.400 1.00 82.32 ? 99 TRP C CZ3 1 ATOM 586 C CH2 . TRP A 1 75 ? -164.947 -145.918 208.947 1.00 83.54 ? 99 TRP C CH2 1 ATOM 587 N N . GLY A 1 76 ? -171.448 -150.087 206.527 1.00 89.01 ? 100 GLY C N 1 ATOM 588 C CA . GLY A 1 76 ? -172.833 -150.381 206.839 1.00 89.00 ? 100 GLY C CA 1 ATOM 589 C C . GLY A 1 76 ? -172.959 -151.276 208.059 1.00 92.50 ? 100 GLY C C 1 ATOM 590 O O . GLY A 1 76 ? -173.809 -151.038 208.919 1.00 96.14 ? 100 GLY C O 1 ATOM 591 N N . ARG A 1 77 ? -172.089 -152.283 208.152 1.00 92.71 ? 101 ARG C N 1 ATOM 592 C CA . ARG A 1 77 ? -172.050 -153.187 209.303 1.00 88.33 ? 101 ARG C CA 1 ATOM 593 C C . ARG A 1 77 ? -171.508 -152.523 210.573 1.00 90.37 ? 101 ARG C C 1 ATOM 594 O O . ARG A 1 77 ? -171.807 -152.953 211.685 1.00 99.13 ? 101 ARG C O 1 ATOM 595 C CB . ARG A 1 77 ? -171.211 -154.435 208.971 1.00 83.08 ? 101 ARG C CB 1 ATOM 596 C CG . ARG A 1 77 ? -171.955 -155.459 208.114 1.00 84.20 ? 101 ARG C CG 1 ATOM 597 C CD . ARG A 1 77 ? -171.236 -156.787 208.003 1.00 88.08 ? 101 ARG C CD 1 ATOM 598 N NE . ARG A 1 77 ? -171.987 -157.733 207.179 1.00 94.73 ? 101 ARG C NE 1 ATOM 599 C CZ . ARG A 1 77 ? -171.633 -158.999 206.968 1.00 99.53 ? 101 ARG C CZ 1 ATOM 600 N NH1 . ARG A 1 77 ? -170.531 -159.486 207.517 1.00 99.19 ? 101 ARG C NH1 1 ATOM 601 N NH2 . ARG A 1 77 ? -172.386 -159.785 206.208 1.00 102.96 ? 101 ARG C NH2 1 ATOM 602 N N . LEU A 1 78 ? -170.702 -151.487 210.410 1.00 86.11 ? 102 LEU C N 1 ATOM 603 C CA . LEU A 1 78 ? -170.076 -150.860 211.556 1.00 87.22 ? 102 LEU C CA 1 ATOM 604 C C . LEU A 1 78 ? -170.957 -149.770 212.192 1.00 91.29 ? 102 LEU C C 1 ATOM 605 O O . LEU A 1 78 ? -171.096 -149.692 213.413 1.00 93.98 ? 102 LEU C O 1 ATOM 606 C CB . LEU A 1 78 ? -168.722 -150.302 211.127 1.00 88.38 ? 102 LEU C CB 1 ATOM 607 C CG . LEU A 1 78 ? -167.773 -149.848 212.229 1.00 95.19 ? 102 LEU C CG 1 ATOM 608 C CD1 . LEU A 1 78 ? -166.348 -150.046 211.753 1.00 97.37 ? 102 LEU C CD1 1 ATOM 609 C CD2 . LEU A 1 78 ? -168.022 -148.385 212.573 1.00 91.49 ? 102 LEU C CD2 1 ATOM 610 N N . VAL A 1 79 ? -171.552 -148.934 211.351 1.00 93.13 ? 103 VAL C N 1 ATOM 611 C CA . VAL A 1 79 ? -172.483 -147.896 211.784 1.00 91.34 ? 103 VAL C CA 1 ATOM 612 C C . VAL A 1 79 ? -173.462 -147.648 210.638 1.00 92.73 ? 103 VAL C C 1 ATOM 613 O O . VAL A 1 79 ? -173.191 -146.821 209.769 1.00 93.53 ? 103 VAL C O 1 ATOM 614 C CB . VAL A 1 79 ? -171.776 -146.580 212.159 1.00 88.59 ? 103 VAL C CB 1 ATOM 615 C CG1 . VAL A 1 79 ? -172.790 -145.482 212.413 1.00 87.68 ? 103 VAL C CG1 1 ATOM 616 C CG2 . VAL A 1 79 ? -170.893 -146.773 213.378 1.00 93.27 ? 103 VAL C CG2 1 ATOM 617 N N . PRO A 1 80 ? -174.617 -148.335 210.649 1.00 94.99 ? 104 PRO C N 1 ATOM 618 C CA . PRO A 1 80 ? -175.533 -148.380 209.503 1.00 96.88 ? 104 PRO C CA 1 ATOM 619 C C . PRO A 1 80 ? -175.997 -146.988 209.100 1.00 92.21 ? 104 PRO C C 1 ATOM 620 O O . PRO A 1 80 ? -176.251 -146.720 207.919 1.00 90.27 ? 104 PRO C O 1 ATOM 621 C CB . PRO A 1 80 ? -176.701 -149.224 210.018 1.00 95.14 ? 104 PRO C CB 1 ATOM 622 C CG . PRO A 1 80 ? -176.093 -150.104 211.045 1.00 91.36 ? 104 PRO C CG 1 ATOM 623 C CD . PRO A 1 80 ? -175.027 -149.268 211.713 1.00 92.98 ? 104 PRO C CD 1 ATOM 624 N N . LEU A 1 81 ? -176.097 -146.103 210.083 1.00 92.35 ? 105 LEU C N 1 ATOM 625 C CA . LEU A 1 81 ? -176.495 -144.721 209.846 1.00 93.15 ? 105 LEU C CA 1 ATOM 626 C C . LEU A 1 81 ? -175.530 -144.067 208.865 1.00 93.87 ? 105 LEU C C 1 ATOM 627 O O . LEU A 1 81 ? -175.878 -143.120 208.165 1.00 98.32 ? 105 LEU C O 1 ATOM 628 C CB . LEU A 1 81 ? -176.521 -143.948 211.166 1.00 93.14 ? 105 LEU C CB 1 ATOM 629 C CG . LEU A 1 81 ? -176.733 -142.445 211.062 1.00 93.44 ? 105 LEU C CG 1 ATOM 630 C CD1 . LEU A 1 81 ? -178.116 -142.195 210.489 1.00 99.21 ? 105 LEU C CD1 1 ATOM 631 C CD2 . LEU A 1 81 ? -176.545 -141.734 212.410 1.00 82.61 ? 105 LEU C CD2 1 ATOM 632 N N . PHE A 1 82 ? -174.311 -144.584 208.817 1.00 96.51 ? 106 PHE C N 1 ATOM 633 C CA . PHE A 1 82 ? -173.297 -144.039 207.936 1.00 88.09 ? 106 PHE C CA 1 ATOM 634 C C . PHE A 1 82 ? -172.890 -145.006 206.834 1.00 84.81 ? 106 PHE C C 1 ATOM 635 O O . PHE A 1 82 ? -171.746 -144.987 206.400 1.00 87.67 ? 106 PHE C O 1 ATOM 636 C CB . PHE A 1 82 ? -172.070 -143.638 208.745 1.00 83.23 ? 106 PHE C CB 1 ATOM 637 C CG . PHE A 1 82 ? -172.247 -142.372 209.527 1.00 88.98 ? 106 PHE C CG 1 ATOM 638 C CD1 . PHE A 1 82 ? -173.129 -141.393 209.104 1.00 93.13 ? 106 PHE C CD1 1 ATOM 639 C CD2 . PHE A 1 82 ? -171.512 -142.152 210.679 1.00 89.39 ? 106 PHE C CD2 1 ATOM 640 C CE1 . PHE A 1 82 ? -173.273 -140.214 209.822 1.00 89.20 ? 106 PHE C CE1 1 ATOM 641 C CE2 . PHE A 1 82 ? -171.658 -140.990 211.402 1.00 89.16 ? 106 PHE C CE2 1 ATOM 642 C CZ . PHE A 1 82 ? -172.543 -140.017 210.974 1.00 81.54 ? 106 PHE C CZ 1 ATOM 643 N N . LYS A 1 83 ? -173.814 -145.835 206.361 1.00 86.75 ? 107 LYS C N 1 ATOM 644 C CA . LYS A 1 83 ? -173.480 -146.758 205.280 1.00 88.92 ? 107 LYS C CA 1 ATOM 645 C C . LYS A 1 83 ? -173.068 -145.956 204.049 1.00 92.81 ? 107 LYS C C 1 ATOM 646 O O . LYS A 1 83 ? -172.369 -146.457 203.164 1.00 94.86 ? 107 LYS C O 1 ATOM 647 C CB . LYS A 1 83 ? -174.650 -147.694 204.942 1.00 88.96 ? 107 LYS C CB 1 ATOM 648 C CG . LYS A 1 83 ? -174.262 -148.777 203.938 1.00 90.00 ? 107 LYS C CG 1 ATOM 649 C CD . LYS A 1 83 ? -175.413 -149.677 203.511 1.00 89.77 ? 107 LYS C CD 1 ATOM 650 C CE . LYS A 1 83 ? -174.855 -150.858 202.717 1.00 95.78 ? 107 LYS C CE 1 ATOM 651 N NZ . LYS A 1 83 ? -175.871 -151.842 202.257 1.00 100.83 ? 107 LYS C NZ 1 ATOM 652 N N . GLY A 1 84 ? -173.497 -144.700 204.010 1.00 92.68 ? 108 GLY C N 1 ATOM 653 C CA . GLY A 1 84 ? -173.264 -143.861 202.856 1.00 93.48 ? 108 GLY C CA 1 ATOM 654 C C . GLY A 1 84 ? -171.787 -143.608 202.644 1.00 91.58 ? 108 GLY C C 1 ATOM 655 O O . GLY A 1 84 ? -171.347 -143.419 201.503 1.00 92.22 ? 108 GLY C O 1 ATOM 656 N N . ILE A 1 85 ? -171.013 -143.641 203.726 1.00 86.59 ? 109 ILE C N 1 ATOM 657 C CA . ILE A 1 85 ? -169.585 -143.384 203.628 1.00 82.73 ? 109 ILE C CA 1 ATOM 658 C C . ILE A 1 85 ? -168.965 -144.367 202.658 1.00 84.24 ? 109 ILE C C 1 ATOM 659 O O . ILE A 1 85 ? -168.041 -144.033 201.925 1.00 82.95 ? 109 ILE C O 1 ATOM 660 C CB . ILE A 1 85 ? -168.880 -143.537 204.978 1.00 80.75 ? 109 ILE C CB 1 ATOM 661 C CG1 . ILE A 1 85 ? -169.341 -142.466 205.963 1.00 80.83 ? 109 ILE C CG1 1 ATOM 662 C CG2 . ILE A 1 85 ? -167.370 -143.520 204.782 1.00 82.45 ? 109 ILE C CG2 1 ATOM 663 C CD1 . ILE A 1 85 ? -168.675 -142.571 207.313 1.00 80.41 ? 109 ILE C CD1 1 ATOM 664 N N . GLY A 1 86 ? -169.504 -145.578 202.643 1.00 85.35 ? 110 GLY C N 1 ATOM 665 C CA . GLY A 1 86 ? -168.992 -146.605 201.771 1.00 81.10 ? 110 GLY C CA 1 ATOM 666 C C . GLY A 1 86 ? -169.333 -146.294 200.340 1.00 83.80 ? 110 GLY C C 1 ATOM 667 O O . GLY A 1 86 ? -168.536 -146.541 199.442 1.00 86.94 ? 110 GLY C O 1 ATOM 668 N N . TYR A 1 87 ? -170.515 -145.738 200.118 1.00 87.83 ? 111 TYR C N 1 ATOM 669 C CA . TYR A 1 87 ? -170.888 -145.350 198.765 1.00 89.18 ? 111 TYR C CA 1 ATOM 670 C C . TYR A 1 87 ? -170.033 -144.178 198.293 1.00 83.51 ? 111 TYR C C 1 ATOM 671 O O . TYR A 1 87 ? -169.572 -144.150 197.152 1.00 85.26 ? 111 TYR C O 1 ATOM 672 C CB . TYR A 1 87 ? -172.382 -144.999 198.685 1.00 91.56 ? 111 TYR C CB 1 ATOM 673 C CG . TYR A 1 87 ? -173.292 -146.210 198.766 1.00 91.88 ? 111 TYR C CG 1 ATOM 674 C CD1 . TYR A 1 87 ? -173.273 -147.186 197.768 1.00 90.19 ? 111 TYR C CD1 1 ATOM 675 C CD2 . TYR A 1 87 ? -174.167 -146.381 199.834 1.00 92.96 ? 111 TYR C CD2 1 ATOM 676 C CE1 . TYR A 1 87 ? -174.091 -148.300 197.834 1.00 83.25 ? 111 TYR C CE1 1 ATOM 677 C CE2 . TYR A 1 87 ? -174.997 -147.495 199.909 1.00 92.13 ? 111 TYR C CE2 1 ATOM 678 C CZ . TYR A 1 87 ? -174.949 -148.449 198.907 1.00 91.15 ? 111 TYR C CZ 1 ATOM 679 O OH . TYR A 1 87 ? -175.767 -149.549 198.984 1.00 96.40 ? 111 TYR C OH 1 ATOM 680 N N . ALA A 1 88 ? -169.791 -143.230 199.190 1.00 79.72 ? 112 ALA C N 1 ATOM 681 C CA . ALA A 1 88 ? -169.048 -142.031 198.833 1.00 84.15 ? 112 ALA C CA 1 ATOM 682 C C . ALA A 1 88 ? -167.644 -142.417 198.400 1.00 86.12 ? 112 ALA C C 1 ATOM 683 O O . ALA A 1 88 ? -167.169 -142.044 197.318 1.00 87.93 ? 112 ALA C O 1 ATOM 684 C CB . ALA A 1 88 ? -169.001 -141.055 200.011 1.00 80.86 ? 112 ALA C CB 1 ATOM 685 N N . VAL A 1 89 ? -167.010 -143.222 199.239 1.00 84.03 ? 113 VAL C N 1 ATOM 686 C CA . VAL A 1 89 ? -165.657 -143.660 199.007 1.00 80.69 ? 113 VAL C CA 1 ATOM 687 C C . VAL A 1 89 ? -165.567 -144.473 197.730 1.00 79.83 ? 113 VAL C C 1 ATOM 688 O O . VAL A 1 89 ? -164.557 -144.449 197.032 1.00 81.16 ? 113 VAL C O 1 ATOM 689 C CB . VAL A 1 89 ? -165.152 -144.476 200.205 1.00 85.66 ? 113 VAL C CB 1 ATOM 690 C CG1 . VAL A 1 89 ? -163.941 -145.280 199.821 1.00 84.47 ? 113 VAL C CG1 1 ATOM 691 C CG2 . VAL A 1 89 ? -164.850 -143.552 201.380 1.00 83.08 ? 113 VAL C CG2 1 ATOM 692 N N . VAL A 1 90 ? -166.642 -145.169 197.400 1.00 83.56 ? 114 VAL C N 1 ATOM 693 C CA . VAL A 1 90 ? -166.590 -146.047 196.249 1.00 85.18 ? 114 VAL C CA 1 ATOM 694 C C . VAL A 1 90 ? -166.536 -145.270 194.939 1.00 85.40 ? 114 VAL C C 1 ATOM 695 O O . VAL A 1 90 ? -165.730 -145.588 194.061 1.00 87.32 ? 114 VAL C O 1 ATOM 696 C CB . VAL A 1 90 ? -167.779 -147.016 196.230 1.00 86.15 ? 114 VAL C CB 1 ATOM 697 C CG1 . VAL A 1 90 ? -167.958 -147.618 194.841 1.00 77.03 ? 114 VAL C CG1 1 ATOM 698 C CG2 . VAL A 1 90 ? -167.552 -148.119 197.269 1.00 86.49 ? 114 VAL C CG2 1 ATOM 699 N N . LEU A 1 91 ? -167.361 -144.239 194.802 1.00 84.23 ? 115 LEU C N 1 ATOM 700 C CA . LEU A 1 91 ? -167.387 -143.516 193.535 1.00 88.08 ? 115 LEU C CA 1 ATOM 701 C C . LEU A 1 91 ? -166.397 -142.358 193.495 1.00 85.38 ? 115 LEU C C 1 ATOM 702 O O . LEU A 1 91 ? -166.132 -141.808 192.431 1.00 86.77 ? 115 LEU C O 1 ATOM 703 C CB . LEU A 1 91 ? -168.802 -143.033 193.219 1.00 90.59 ? 115 LEU C CB 1 ATOM 704 C CG . LEU A 1 91 ? -169.502 -142.146 194.225 1.00 92.27 ? 115 LEU C CG 1 ATOM 705 C CD1 . LEU A 1 91 ? -169.205 -140.700 193.906 1.00 96.50 ? 115 LEU C CD1 1 ATOM 706 C CD2 . LEU A 1 91 ? -170.994 -142.418 194.174 1.00 96.44 ? 115 LEU C CD2 1 ATOM 707 N N . ILE A 1 92 ? -165.829 -141.992 194.636 1.00 81.98 ? 116 ILE C N 1 ATOM 708 C CA . ILE A 1 92 ? -164.618 -141.180 194.583 1.00 78.61 ? 116 ILE C CA 1 ATOM 709 C C . ILE A 1 92 ? -163.511 -141.993 193.893 1.00 81.31 ? 116 ILE C C 1 ATOM 710 O O . ILE A 1 92 ? -162.830 -141.504 192.995 1.00 79.93 ? 116 ILE C O 1 ATOM 711 C CB . ILE A 1 92 ? -164.132 -140.759 195.972 1.00 77.25 ? 116 ILE C CB 1 ATOM 712 C CG1 . ILE A 1 92 ? -165.049 -139.697 196.568 1.00 79.69 ? 116 ILE C CG1 1 ATOM 713 C CG2 . ILE A 1 92 ? -162.704 -140.250 195.899 1.00 71.94 ? 116 ILE C CG2 1 ATOM 714 C CD1 . ILE A 1 92 ? -164.651 -139.276 197.969 1.00 78.05 ? 116 ILE C CD1 1 ATOM 715 N N . ALA A 1 93 ? -163.361 -143.254 194.293 1.00 81.08 ? 117 ALA C N 1 ATOM 716 C CA . ALA A 1 93 ? -162.391 -144.148 193.668 1.00 76.62 ? 117 ALA C CA 1 ATOM 717 C C . ALA A 1 93 ? -162.737 -144.365 192.211 1.00 82.18 ? 117 ALA C C 1 ATOM 718 O O . ALA A 1 93 ? -161.852 -144.616 191.380 1.00 79.77 ? 117 ALA C O 1 ATOM 719 C CB . ALA A 1 93 ? -162.346 -145.472 194.395 1.00 73.18 ? 117 ALA C CB 1 ATOM 720 N N . PHE A 1 94 ? -164.041 -144.279 191.931 1.00 86.96 ? 118 PHE C N 1 ATOM 721 C CA . PHE A 1 94 ? -164.610 -144.446 190.593 1.00 88.08 ? 118 PHE C CA 1 ATOM 722 C C . PHE A 1 94 ? -164.229 -143.283 189.664 1.00 87.99 ? 118 PHE C C 1 ATOM 723 O O . PHE A 1 94 ? -163.770 -143.505 188.544 1.00 85.34 ? 118 PHE C O 1 ATOM 724 C CB . PHE A 1 94 ? -166.137 -144.578 190.714 1.00 87.53 ? 118 PHE C CB 1 ATOM 725 C CG . PHE A 1 94 ? -166.868 -144.674 189.394 1.00 90.72 ? 118 PHE C CG 1 ATOM 726 C CD1 . PHE A 1 94 ? -166.710 -145.781 188.571 1.00 91.16 ? 118 PHE C CD1 1 ATOM 727 C CD2 . PHE A 1 94 ? -167.752 -143.670 189.000 1.00 90.87 ? 118 PHE C CD2 1 ATOM 728 C CE1 . PHE A 1 94 ? -167.398 -145.876 187.365 1.00 96.43 ? 118 PHE C CE1 1 ATOM 729 C CE2 . PHE A 1 94 ? -168.446 -143.754 187.799 1.00 86.70 ? 118 PHE C CE2 1 ATOM 730 C CZ . PHE A 1 94 ? -168.267 -144.860 186.978 1.00 96.40 ? 118 PHE C CZ 1 ATOM 731 N N . TYR A 1 95 ? -164.394 -142.050 190.150 1.00 84.14 ? 119 TYR C N 1 ATOM 732 C CA . TYR A 1 95 ? -163.979 -140.854 189.412 1.00 83.74 ? 119 TYR C CA 1 ATOM 733 C C . TYR A 1 95 ? -162.480 -140.828 189.156 1.00 86.18 ? 119 TYR C C 1 ATOM 734 O O . TYR A 1 95 ? -162.035 -140.530 188.042 1.00 89.64 ? 119 TYR C O 1 ATOM 735 C CB . TYR A 1 95 ? -164.343 -139.581 190.171 1.00 79.31 ? 119 TYR C CB 1 ATOM 736 C CG . TYR A 1 95 ? -165.819 -139.363 190.361 1.00 85.93 ? 119 TYR C CG 1 ATOM 737 C CD1 . TYR A 1 95 ? -166.733 -139.721 189.374 1.00 85.89 ? 119 TYR C CD1 1 ATOM 738 C CD2 . TYR A 1 95 ? -166.305 -138.794 191.533 1.00 85.08 ? 119 TYR C CD2 1 ATOM 739 C CE1 . TYR A 1 95 ? -168.085 -139.515 189.552 1.00 84.96 ? 119 TYR C CE1 1 ATOM 740 C CE2 . TYR A 1 95 ? -167.655 -138.591 191.718 1.00 87.04 ? 119 TYR C CE2 1 ATOM 741 C CZ . TYR A 1 95 ? -168.540 -138.956 190.726 1.00 89.87 ? 119 TYR C CZ 1 ATOM 742 O OH . TYR A 1 95 ? -169.887 -138.744 190.915 1.00 94.84 ? 119 TYR C OH 1 ATOM 743 N N . VAL A 1 96 ? -161.707 -141.168 190.185 1.00 81.24 ? 120 VAL C N 1 ATOM 744 C CA . VAL A 1 96 ? -160.261 -141.058 190.116 1.00 79.21 ? 120 VAL C CA 1 ATOM 745 C C . VAL A 1 96 ? -159.720 -141.936 188.991 1.00 83.28 ? 120 VAL C C 1 ATOM 746 O O . VAL A 1 96 ? -158.713 -141.612 188.375 1.00 81.52 ? 120 VAL C O 1 ATOM 747 C CB . VAL A 1 96 ? -159.600 -141.449 191.458 1.00 69.96 ? 120 VAL C CB 1 ATOM 748 C CG1 . VAL A 1 96 ? -158.091 -141.398 191.341 1.00 67.17 ? 120 VAL C CG1 1 ATOM 749 C CG2 . VAL A 1 96 ? -160.059 -140.539 192.549 1.00 67.15 ? 120 VAL C CG2 1 ATOM 750 N N . ASP A 1 97 ? -160.407 -143.036 188.705 1.00 85.66 ? 121 ASP C N 1 ATOM 751 C CA . ASP A 1 97 ? -159.979 -143.895 187.602 1.00 93.66 ? 121 ASP C CA 1 ATOM 752 C C . ASP A 1 97 ? -160.181 -143.211 186.239 1.00 95.99 ? 121 ASP C C 1 ATOM 753 O O . ASP A 1 97 ? -159.498 -143.538 185.265 1.00 96.99 ? 121 ASP C O 1 ATOM 754 C CB . ASP A 1 97 ? -160.701 -145.245 187.645 1.00 91.19 ? 121 ASP C CB 1 ATOM 755 C CG . ASP A 1 97 ? -159.918 -146.309 188.444 1.00 101.23 ? 121 ASP C CG 1 ATOM 756 O OD1 . ASP A 1 97 ? -158.658 -146.297 188.410 1.00 97.82 ? 121 ASP C OD1 1 ATOM 757 O OD2 . ASP A 1 97 ? -160.561 -147.166 189.105 1.00 101.16 ? 121 ASP C OD2 1 ATOM 758 N N . PHE A 1 98 ? -161.100 -142.249 186.176 1.00 93.21 ? 122 PHE C N 1 ATOM 759 C CA . PHE A 1 98 ? -161.384 -141.560 184.920 1.00 90.23 ? 122 PHE C CA 1 ATOM 760 C C . PHE A 1 98 ? -160.220 -140.712 184.422 1.00 91.25 ? 122 PHE C C 1 ATOM 761 O O . PHE A 1 98 ? -160.113 -140.456 183.217 1.00 97.69 ? 122 PHE C O 1 ATOM 762 C CB . PHE A 1 98 ? -162.630 -140.689 185.052 1.00 91.46 ? 122 PHE C CB 1 ATOM 763 C CG . PHE A 1 98 ? -163.915 -141.468 185.002 1.00 89.99 ? 122 PHE C CG 1 ATOM 764 C CD1 . PHE A 1 98 ? -164.211 -142.264 183.909 1.00 89.29 ? 122 PHE C CD1 1 ATOM 765 C CD2 . PHE A 1 98 ? -164.827 -141.402 186.045 1.00 94.88 ? 122 PHE C CD2 1 ATOM 766 C CE1 . PHE A 1 98 ? -165.384 -142.982 183.858 1.00 92.02 ? 122 PHE C CE1 1 ATOM 767 C CE2 . PHE A 1 98 ? -166.006 -142.122 186.003 1.00 94.17 ? 122 PHE C CE2 1 ATOM 768 C CZ . PHE A 1 98 ? -166.283 -142.914 184.908 1.00 95.53 ? 122 PHE C CZ 1 ATOM 769 N N . TYR A 1 99 ? -159.345 -140.272 185.324 1.00 89.43 ? 123 TYR C N 1 ATOM 770 C CA . TYR A 1 99 ? -158.210 -139.453 184.882 1.00 90.32 ? 123 TYR C CA 1 ATOM 771 C C . TYR A 1 99 ? -156.838 -140.033 185.224 1.00 85.02 ? 123 TYR C C 1 ATOM 772 O O . TYR A 1 99 ? -155.918 -139.944 184.418 1.00 89.95 ? 123 TYR C O 1 ATOM 773 C CB . TYR A 1 99 ? -158.324 -138.026 185.444 1.00 81.90 ? 123 TYR C CB 1 ATOM 774 C CG . TYR A 1 99 ? -158.124 -137.895 186.935 1.00 82.52 ? 123 TYR C CG 1 ATOM 775 C CD1 . TYR A 1 99 ? -156.852 -137.742 187.482 1.00 82.10 ? 123 TYR C CD1 1 ATOM 776 C CD2 . TYR A 1 99 ? -159.211 -137.904 187.799 1.00 85.26 ? 123 TYR C CD2 1 ATOM 777 C CE1 . TYR A 1 99 ? -156.671 -137.612 188.855 1.00 82.02 ? 123 TYR C CE1 1 ATOM 778 C CE2 . TYR A 1 99 ? -159.041 -137.773 189.171 1.00 82.51 ? 123 TYR C CE2 1 ATOM 779 C CZ . TYR A 1 99 ? -157.769 -137.623 189.693 1.00 81.93 ? 123 TYR C CZ 1 ATOM 780 O OH . TYR A 1 99 ? -157.601 -137.480 191.056 1.00 80.85 ? 123 TYR C OH 1 ATOM 781 N N . TYR A 1 100 ? -156.702 -140.635 186.397 1.00 83.58 ? 124 TYR C N 1 ATOM 782 C CA . TYR A 1 100 ? -155.394 -141.043 186.899 1.00 78.04 ? 124 TYR C CA 1 ATOM 783 C C . TYR A 1 100 ? -154.660 -141.985 185.938 1.00 82.14 ? 124 TYR C C 1 ATOM 784 O O . TYR A 1 100 ? -153.425 -141.962 185.839 1.00 79.80 ? 124 TYR C O 1 ATOM 785 C CB . TYR A 1 100 ? -155.557 -141.727 188.259 1.00 80.40 ? 124 TYR C CB 1 ATOM 786 C CG . TYR A 1 100 ? -154.254 -142.056 188.944 1.00 78.70 ? 124 TYR C CG 1 ATOM 787 C CD1 . TYR A 1 100 ? -153.730 -141.201 189.899 1.00 82.30 ? 124 TYR C CD1 1 ATOM 788 C CD2 . TYR A 1 100 ? -153.547 -143.215 188.636 1.00 79.07 ? 124 TYR C CD2 1 ATOM 789 C CE1 . TYR A 1 100 ? -152.543 -141.480 190.532 1.00 87.35 ? 124 TYR C CE1 1 ATOM 790 C CE2 . TYR A 1 100 ? -152.345 -143.509 189.265 1.00 81.15 ? 124 TYR C CE2 1 ATOM 791 C CZ . TYR A 1 100 ? -151.851 -142.632 190.213 1.00 82.89 ? 124 TYR C CZ 1 ATOM 792 O OH . TYR A 1 100 ? -150.661 -142.881 190.846 1.00 80.15 ? 124 TYR C OH 1 ATOM 793 N N . ASN A 1 101 ? -155.423 -142.808 185.224 1.00 86.44 ? 125 ASN C N 1 ATOM 794 C CA . ASN A 1 101 ? -154.841 -143.730 184.254 1.00 81.28 ? 125 ASN C CA 1 ATOM 795 C C . ASN A 1 101 ? -154.170 -142.991 183.097 1.00 81.33 ? 125 ASN C C 1 ATOM 796 O O . ASN A 1 101 ? -153.252 -143.508 182.456 1.00 80.88 ? 125 ASN C O 1 ATOM 797 C CB . ASN A 1 101 ? -155.907 -144.690 183.723 1.00 83.37 ? 125 ASN C CB 1 ATOM 798 C CG . ASN A 1 101 ? -156.412 -145.646 184.789 1.00 90.12 ? 125 ASN C CG 1 ATOM 799 O OD1 . ASN A 1 101 ? -155.714 -146.588 185.173 1.00 90.34 ? 125 ASN C OD1 1 ATOM 800 N ND2 . ASN A 1 101 ? -157.634 -145.421 185.259 1.00 89.79 ? 125 ASN C ND2 1 ATOM 801 N N . VAL A 1 102 ? -154.632 -141.774 182.834 1.00 79.82 ? 126 VAL C N 1 ATOM 802 C CA . VAL A 1 102 ? -154.062 -140.976 181.760 1.00 76.97 ? 126 VAL C CA 1 ATOM 803 C C . VAL A 1 102 ? -152.577 -140.678 181.976 1.00 75.88 ? 126 VAL C C 1 ATOM 804 O O . VAL A 1 102 ? -151.813 -140.591 181.007 1.00 70.72 ? 126 VAL C O 1 ATOM 805 C CB . VAL A 1 102 ? -154.812 -139.662 181.609 1.00 78.84 ? 126 VAL C CB 1 ATOM 806 C CG1 . VAL A 1 102 ? -154.308 -138.915 180.394 1.00 81.49 ? 126 VAL C CG1 1 ATOM 807 C CG2 . VAL A 1 102 ? -156.288 -139.946 181.477 1.00 89.43 ? 126 VAL C CG2 1 ATOM 808 N N . ILE A 1 103 ? -152.168 -140.532 183.236 1.00 74.07 ? 127 ILE C N 1 ATOM 809 C CA . ILE A 1 103 ? -150.762 -140.325 183.554 1.00 72.66 ? 127 ILE C CA 1 ATOM 810 C C . ILE A 1 103 ? -149.930 -141.545 183.173 1.00 74.82 ? 127 ILE C C 1 ATOM 811 O O . ILE A 1 103 ? -148.795 -141.426 182.692 1.00 72.64 ? 127 ILE C O 1 ATOM 812 C CB . ILE A 1 103 ? -150.554 -140.053 185.044 1.00 74.82 ? 127 ILE C CB 1 ATOM 813 C CG1 . ILE A 1 103 ? -151.345 -138.830 185.494 1.00 77.63 ? 127 ILE C CG1 1 ATOM 814 C CG2 . ILE A 1 103 ? -149.067 -139.876 185.345 1.00 73.86 ? 127 ILE C CG2 1 ATOM 815 C CD1 . ILE A 1 103 ? -151.095 -138.473 186.951 1.00 78.31 ? 127 ILE C CD1 1 ATOM 816 N N . ILE A 1 104 ? -150.506 -142.722 183.374 1.00 73.64 ? 128 ILE C N 1 ATOM 817 C CA . ILE A 1 104 ? -149.810 -143.948 183.036 1.00 74.68 ? 128 ILE C CA 1 ATOM 818 C C . ILE A 1 104 ? -149.633 -144.018 181.532 1.00 77.05 ? 128 ILE C C 1 ATOM 819 O O . ILE A 1 104 ? -148.553 -144.341 181.026 1.00 75.03 ? 128 ILE C O 1 ATOM 820 C CB . ILE A 1 104 ? -150.583 -145.167 183.526 1.00 71.16 ? 128 ILE C CB 1 ATOM 821 C CG1 . ILE A 1 104 ? -151.062 -144.921 184.962 1.00 72.19 ? 128 ILE C CG1 1 ATOM 822 C CG2 . ILE A 1 104 ? -149.730 -146.405 183.409 1.00 68.34 ? 128 ILE C CG2 1 ATOM 823 C CD1 . ILE A 1 104 ? -151.728 -146.112 185.616 1.00 77.01 ? 128 ILE C CD1 1 ATOM 824 N N . ALA A 1 105 ? -150.704 -143.659 180.826 1.00 80.01 ? 129 ALA C N 1 ATOM 825 C CA . ALA A 1 105 ? -150.714 -143.663 179.370 1.00 73.59 ? 129 ALA C CA 1 ATOM 826 C C . ALA A 1 105 ? -149.688 -142.686 178.801 1.00 74.29 ? 129 ALA C C 1 ATOM 827 O O . ALA A 1 105 ? -149.008 -143.004 177.831 1.00 77.62 ? 129 ALA C O 1 ATOM 828 C CB . ALA A 1 105 ? -152.110 -143.326 178.863 1.00 70.52 ? 129 ALA C CB 1 ATOM 829 N N . TRP A 1 106 ? -149.546 -141.519 179.431 1.00 72.17 ? 130 TRP C N 1 ATOM 830 C CA . TRP A 1 106 ? -148.511 -140.572 179.038 1.00 70.79 ? 130 TRP C CA 1 ATOM 831 C C . TRP A 1 106 ? -147.144 -141.215 179.248 1.00 75.09 ? 130 TRP C C 1 ATOM 832 O O . TRP A 1 106 ? -146.219 -141.030 178.449 1.00 73.53 ? 130 TRP C O 1 ATOM 833 C CB . TRP A 1 106 ? -148.595 -139.276 179.851 1.00 66.34 ? 130 TRP C CB 1 ATOM 834 C CG . TRP A 1 106 ? -149.792 -138.443 179.555 1.00 71.17 ? 130 TRP C CG 1 ATOM 835 C CD1 . TRP A 1 106 ? -150.523 -138.451 178.414 1.00 76.07 ? 130 TRP C CD1 1 ATOM 836 C CD2 . TRP A 1 106 ? -150.411 -137.475 180.423 1.00 70.93 ? 130 TRP C CD2 1 ATOM 837 N NE1 . TRP A 1 106 ? -151.570 -137.551 178.509 1.00 77.22 ? 130 TRP C NE1 1 ATOM 838 C CE2 . TRP A 1 106 ? -151.516 -136.939 179.734 1.00 70.76 ? 130 TRP C CE2 1 ATOM 839 C CE3 . TRP A 1 106 ? -150.135 -137.013 181.712 1.00 72.58 ? 130 TRP C CE3 1 ATOM 840 C CZ2 . TRP A 1 106 ? -152.344 -135.966 180.294 1.00 72.80 ? 130 TRP C CZ2 1 ATOM 841 C CZ3 . TRP A 1 106 ? -150.958 -136.041 182.265 1.00 71.91 ? 130 TRP C CZ3 1 ATOM 842 C CH2 . TRP A 1 106 ? -152.051 -135.533 181.558 1.00 72.63 ? 130 TRP C CH2 1 ATOM 843 N N . SER A 1 107 ? -147.030 -142.002 180.313 1.00 74.40 ? 131 SER C N 1 ATOM 844 C CA . SER A 1 107 ? -145.780 -142.685 180.603 1.00 71.95 ? 131 SER C CA 1 ATOM 845 C C . SER A 1 107 ? -145.476 -143.716 179.534 1.00 75.41 ? 131 SER C C 1 ATOM 846 O O . SER A 1 107 ? -144.343 -143.812 179.056 1.00 74.44 ? 131 SER C O 1 ATOM 847 C CB . SER A 1 107 ? -145.854 -143.350 181.965 1.00 75.49 ? 131 SER C CB 1 ATOM 848 O OG . SER A 1 107 ? -146.443 -142.460 182.893 1.00 81.58 ? 131 SER C OG 1 ATOM 849 N N . LEU A 1 108 ? -146.491 -144.489 179.150 1.00 75.22 ? 132 LEU C N 1 ATOM 850 C CA . LEU A 1 108 ? -146.302 -145.447 178.073 1.00 75.55 ? 132 LEU C CA 1 ATOM 851 C C . LEU A 1 108 ? -146.018 -144.726 176.774 1.00 79.18 ? 132 LEU C C 1 ATOM 852 O O . LEU A 1 108 ? -145.209 -145.189 175.966 1.00 82.38 ? 132 LEU C O 1 ATOM 853 C CB . LEU A 1 108 ? -147.526 -146.342 177.906 1.00 81.32 ? 132 LEU C CB 1 ATOM 854 C CG . LEU A 1 108 ? -147.730 -147.452 178.940 1.00 80.34 ? 132 LEU C CG 1 ATOM 855 C CD1 . LEU A 1 108 ? -148.939 -148.287 178.552 1.00 76.56 ? 132 LEU C CD1 1 ATOM 856 C CD2 . LEU A 1 108 ? -146.473 -148.307 179.063 1.00 73.27 ? 132 LEU C CD2 1 ATOM 857 N N . ARG A 1 109 ? -146.670 -143.579 176.585 1.00 76.04 ? 133 ARG C N 1 ATOM 858 C CA . ARG A 1 109 ? -146.532 -142.838 175.340 1.00 74.80 ? 133 ARG C CA 1 ATOM 859 C C . ARG A 1 109 ? -145.119 -142.313 175.162 1.00 77.14 ? 133 ARG C C 1 ATOM 860 O O . ARG A 1 109 ? -144.594 -142.308 174.049 1.00 76.20 ? 133 ARG C O 1 ATOM 861 C CB . ARG A 1 109 ? -147.524 -141.680 175.284 1.00 75.39 ? 133 ARG C CB 1 ATOM 862 C CG . ARG A 1 109 ? -147.474 -140.910 173.976 1.00 76.54 ? 133 ARG C CG 1 ATOM 863 C CD . ARG A 1 109 ? -147.640 -141.859 172.817 1.00 76.88 ? 133 ARG C CD 1 ATOM 864 N NE . ARG A 1 109 ? -147.528 -141.197 171.522 1.00 76.81 ? 133 ARG C NE 1 ATOM 865 C CZ . ARG A 1 109 ? -146.435 -141.210 170.770 1.00 80.53 ? 133 ARG C CZ 1 ATOM 866 N NH1 . ARG A 1 109 ? -145.348 -141.842 171.194 1.00 78.64 ? 133 ARG C NH1 1 ATOM 867 N NH2 . ARG A 1 109 ? -146.424 -140.586 169.598 1.00 83.17 ? 133 ARG C NH2 1 ATOM 868 N N . PHE A 1 110 ? -144.509 -141.872 176.261 1.00 76.01 ? 134 PHE C N 1 ATOM 869 C CA . PHE A 1 110 ? -143.120 -141.445 176.235 1.00 71.71 ? 134 PHE C CA 1 ATOM 870 C C . PHE A 1 110 ? -142.195 -142.638 176.113 1.00 76.54 ? 134 PHE C C 1 ATOM 871 O O . PHE A 1 110 ? -141.121 -142.530 175.536 1.00 77.79 ? 134 PHE C O 1 ATOM 872 C CB . PHE A 1 110 ? -142.766 -140.646 177.489 1.00 76.68 ? 134 PHE C CB 1 ATOM 873 C CG . PHE A 1 110 ? -143.080 -139.184 177.390 1.00 76.71 ? 134 PHE C CG 1 ATOM 874 C CD1 . PHE A 1 110 ? -143.290 -138.593 176.177 1.00 85.15 ? 134 PHE C CD1 1 ATOM 875 C CD2 . PHE A 1 110 ? -143.158 -138.402 178.515 1.00 86.38 ? 134 PHE C CD2 1 ATOM 876 C CE1 . PHE A 1 110 ? -143.581 -137.253 176.086 1.00 80.91 ? 134 PHE C CE1 1 ATOM 877 C CE2 . PHE A 1 110 ? -143.454 -137.051 178.420 1.00 82.69 ? 134 PHE C CE2 1 ATOM 878 C CZ . PHE A 1 110 ? -143.663 -136.489 177.206 1.00 68.98 ? 134 PHE C CZ 1 ATOM 879 N N . PHE A 1 111 ? -142.610 -143.779 176.662 1.00 77.94 ? 135 PHE C N 1 ATOM 880 C CA . PHE A 1 111 ? -141.794 -144.991 176.586 1.00 81.08 ? 135 PHE C CA 1 ATOM 881 C C . PHE A 1 111 ? -141.684 -145.451 175.133 1.00 83.95 ? 135 PHE C C 1 ATOM 882 O O . PHE A 1 111 ? -140.576 -145.640 174.611 1.00 81.88 ? 135 PHE C O 1 ATOM 883 C CB . PHE A 1 111 ? -142.386 -146.103 177.466 1.00 82.62 ? 135 PHE C CB 1 ATOM 884 C CG . PHE A 1 111 ? -141.613 -147.397 177.424 1.00 80.01 ? 135 PHE C CG 1 ATOM 885 C CD1 . PHE A 1 111 ? -140.416 -147.529 178.116 1.00 83.15 ? 135 PHE C CD1 1 ATOM 886 C CD2 . PHE A 1 111 ? -142.089 -148.485 176.705 1.00 80.97 ? 135 PHE C CD2 1 ATOM 887 C CE1 . PHE A 1 111 ? -139.697 -148.726 178.082 1.00 83.74 ? 135 PHE C CE1 1 ATOM 888 C CE2 . PHE A 1 111 ? -141.375 -149.684 176.662 1.00 80.36 ? 135 PHE C CE2 1 ATOM 889 C CZ . PHE A 1 111 ? -140.178 -149.802 177.350 1.00 79.21 ? 135 PHE C CZ 1 ATOM 890 N N . PHE A 1 112 ? -142.835 -145.556 174.463 1.00 83.14 ? 136 PHE C N 1 ATOM 891 C CA . PHE A 1 112 ? -142.872 -145.969 173.068 1.00 80.95 ? 136 PHE C CA 1 ATOM 892 C C . PHE A 1 112 ? -142.133 -144.926 172.254 1.00 81.11 ? 136 PHE C C 1 ATOM 893 O O . PHE A 1 112 ? -141.633 -145.197 171.171 1.00 88.65 ? 136 PHE C O 1 ATOM 894 C CB . PHE A 1 112 ? -144.306 -146.122 172.568 1.00 79.95 ? 136 PHE C CB 1 ATOM 895 C CG . PHE A 1 112 ? -145.061 -147.281 173.187 1.00 88.96 ? 136 PHE C CG 1 ATOM 896 C CD1 . PHE A 1 112 ? -144.396 -148.433 173.596 1.00 89.89 ? 136 PHE C CD1 1 ATOM 897 C CD2 . PHE A 1 112 ? -146.445 -147.222 173.346 1.00 90.46 ? 136 PHE C CD2 1 ATOM 898 C CE1 . PHE A 1 112 ? -145.099 -149.505 174.159 1.00 87.72 ? 136 PHE C CE1 1 ATOM 899 C CE2 . PHE A 1 112 ? -147.149 -148.286 173.904 1.00 90.31 ? 136 PHE C CE2 1 ATOM 900 C CZ . PHE A 1 112 ? -146.474 -149.428 174.312 1.00 86.83 ? 136 PHE C CZ 1 ATOM 901 N N . ALA A 1 113 ? -142.058 -143.721 172.798 1.00 83.41 ? 137 ALA C N 1 ATOM 902 C CA . ALA A 1 113 ? -141.411 -142.614 172.110 1.00 80.97 ? 137 ALA C CA 1 ATOM 903 C C . ALA A 1 113 ? -139.886 -142.643 172.199 1.00 83.27 ? 137 ALA C C 1 ATOM 904 O O . ALA A 1 113 ? -139.212 -141.923 171.466 1.00 85.00 ? 137 ALA C O 1 ATOM 905 C CB . ALA A 1 113 ? -141.928 -141.311 172.656 1.00 82.49 ? 137 ALA C CB 1 ATOM 906 N N . SER A 1 114 ? -139.339 -143.457 173.097 1.00 83.64 ? 138 SER C N 1 ATOM 907 C CA . SER A 1 114 ? -137.900 -143.417 173.347 1.00 84.55 ? 138 SER C CA 1 ATOM 908 C C . SER A 1 114 ? -137.166 -144.579 172.692 1.00 89.66 ? 138 SER C C 1 ATOM 909 O O . SER A 1 114 ? -135.977 -144.808 172.951 1.00 83.95 ? 138 SER C O 1 ATOM 910 C CB . SER A 1 114 ? -137.618 -143.410 174.845 1.00 78.68 ? 138 SER C CB 1 ATOM 911 O OG . SER A 1 114 ? -138.792 -143.070 175.554 1.00 76.28 ? 138 SER C OG 1 ATOM 912 N N . PHE A 1 115 ? -137.876 -145.332 171.858 1.00 93.97 ? 139 PHE C N 1 ATOM 913 C CA . PHE A 1 115 ? -137.220 -146.374 171.091 1.00 91.20 ? 139 PHE C CA 1 ATOM 914 C C . PHE A 1 115 ? -136.513 -145.700 169.924 1.00 88.51 ? 139 PHE C C 1 ATOM 915 O O . PHE A 1 115 ? -136.950 -145.762 168.782 1.00 92.04 ? 139 PHE C O 1 ATOM 916 C CB . PHE A 1 115 ? -138.226 -147.425 170.622 1.00 87.82 ? 139 PHE C CB 1 ATOM 917 C CG . PHE A 1 115 ? -138.761 -148.285 171.732 1.00 90.72 ? 139 PHE C CG 1 ATOM 918 C CD1 . PHE A 1 115 ? -137.981 -149.288 172.292 1.00 91.54 ? 139 PHE C CD1 1 ATOM 919 C CD2 . PHE A 1 115 ? -140.039 -148.083 172.227 1.00 90.72 ? 139 PHE C CD2 1 ATOM 920 C CE1 . PHE A 1 115 ? -138.467 -150.074 173.319 1.00 93.78 ? 139 PHE C CE1 1 ATOM 921 C CE2 . PHE A 1 115 ? -140.537 -148.869 173.248 1.00 89.64 ? 139 PHE C CE2 1 ATOM 922 C CZ . PHE A 1 115 ? -139.749 -149.866 173.795 1.00 96.17 ? 139 PHE C CZ 1 ATOM 923 N N . THR A 1 116 ? -135.437 -145.005 170.248 1.00 84.85 ? 140 THR C N 1 ATOM 924 C CA . THR A 1 116 ? -134.670 -144.313 169.249 1.00 95.51 ? 140 THR C CA 1 ATOM 925 C C . THR A 1 116 ? -133.331 -143.904 169.752 1.00 93.48 ? 140 THR C C 1 ATOM 926 O O . THR A 1 116 ? -133.085 -143.796 170.959 1.00 86.50 ? 140 THR C O 1 ATOM 927 C CB . THR A 1 116 ? -135.350 -143.031 168.730 1.00 98.84 ? 140 THR C CB 1 ATOM 928 O OG1 . THR A 1 116 ? -134.379 -142.278 167.988 1.00 91.78 ? 140 THR C OG1 1 ATOM 929 C CG2 . THR A 1 116 ? -135.849 -142.173 169.883 1.00 90.06 ? 140 THR C CG2 1 ATOM 930 N N . ASN A 1 117 ? -132.472 -143.660 168.775 1.00 100.48 ? 141 ASN C N 1 ATOM 931 C CA . ASN A 1 117 ? -131.070 -143.370 169.012 1.00 104.62 ? 141 ASN C CA 1 ATOM 932 C C . ASN A 1 117 ? -130.832 -141.880 169.249 1.00 98.64 ? 141 ASN C C 1 ATOM 933 O O . ASN A 1 117 ? -129.752 -141.489 169.676 1.00 98.55 ? 141 ASN C O 1 ATOM 934 C CB . ASN A 1 117 ? -130.219 -143.925 167.835 1.00 109.79 ? 141 ASN C CB 1 ATOM 935 C CG . ASN A 1 117 ? -130.460 -143.200 166.495 1.00 111.45 ? 141 ASN C CG 1 ATOM 936 O OD1 . ASN A 1 117 ? -129.643 -142.333 166.131 1.00 113.11 ? 141 ASN C OD1 1 ATOM 937 N ND2 . ASN A 1 117 ? -131.561 -143.560 165.722 1.00 117.05 ? 141 ASN C ND2 1 ATOM 938 N N . SER A 1 118 ? -131.865 -141.075 168.991 1.00 95.15 ? 142 SER C N 1 ATOM 939 C CA . SER A 1 118 ? -131.861 -139.636 169.247 1.00 95.39 ? 142 SER C CA 1 ATOM 940 C C . SER A 1 118 ? -133.242 -139.147 169.720 1.00 96.51 ? 142 SER C C 1 ATOM 941 O O . SER A 1 118 ? -134.190 -139.038 168.921 1.00 92.86 ? 142 SER C O 1 ATOM 942 C CB . SER A 1 118 ? -131.454 -138.867 167.994 1.00 96.16 ? 142 SER C CB 1 ATOM 943 O OG . SER A 1 118 ? -131.364 -137.469 168.253 1.00 98.71 ? 142 SER C OG 1 ATOM 944 N N . LEU A 1 119 ? -133.341 -138.830 171.012 1.00 89.85 ? 143 LEU C N 1 ATOM 945 C CA . LEU A 1 119 ? -134.615 -138.519 171.654 1.00 79.39 ? 143 LEU C CA 1 ATOM 946 C C . LEU A 1 119 ? -135.231 -137.238 171.104 1.00 81.58 ? 143 LEU C C 1 ATOM 947 O O . LEU A 1 119 ? -134.558 -136.219 171.003 1.00 84.01 ? 143 LEU C O 1 ATOM 948 C CB . LEU A 1 119 ? -134.422 -138.399 173.164 1.00 79.83 ? 143 LEU C CB 1 ATOM 949 C CG . LEU A 1 119 ? -133.991 -139.697 173.852 1.00 79.77 ? 143 LEU C CG 1 ATOM 950 C CD1 . LEU A 1 119 ? -133.592 -139.473 175.309 1.00 75.81 ? 143 LEU C CD1 1 ATOM 951 C CD2 . LEU A 1 119 ? -135.083 -140.755 173.746 1.00 77.59 ? 143 LEU C CD2 1 ATOM 952 N N . PRO A 1 120 ? -136.526 -137.307 170.736 1.00 78.22 ? 144 PRO C N 1 ATOM 953 C CA . PRO A 1 120 ? -137.274 -136.240 170.051 1.00 75.80 ? 144 PRO C CA 1 ATOM 954 C C . PRO A 1 120 ? -137.311 -134.900 170.778 1.00 76.49 ? 144 PRO C C 1 ATOM 955 O O . PRO A 1 120 ? -137.323 -133.852 170.131 1.00 80.61 ? 144 PRO C O 1 ATOM 956 C CB . PRO A 1 120 ? -138.672 -136.809 169.906 1.00 72.36 ? 144 PRO C CB 1 ATOM 957 C CG . PRO A 1 120 ? -138.777 -137.867 170.953 1.00 79.52 ? 144 PRO C CG 1 ATOM 958 C CD . PRO A 1 120 ? -137.394 -138.443 171.073 1.00 77.87 ? 144 PRO C CD 1 ATOM 959 N N . TRP A 1 121 ? -137.337 -134.920 172.106 1.00 74.74 ? 145 TRP C N 1 ATOM 960 C CA . TRP A 1 121 ? -137.648 -133.710 172.861 1.00 73.85 ? 145 TRP C CA 1 ATOM 961 C C . TRP A 1 121 ? -136.419 -132.850 173.095 1.00 72.91 ? 145 TRP C C 1 ATOM 962 O O . TRP A 1 121 ? -136.472 -131.850 173.811 1.00 72.48 ? 145 TRP C O 1 ATOM 963 C CB . TRP A 1 121 ? -138.319 -134.065 174.187 1.00 68.72 ? 145 TRP C CB 1 ATOM 964 C CG . TRP A 1 121 ? -137.566 -135.024 175.049 1.00 69.56 ? 145 TRP C CG 1 ATOM 965 C CD1 . TRP A 1 121 ? -136.544 -134.727 175.904 1.00 72.59 ? 145 TRP C CD1 1 ATOM 966 C CD2 . TRP A 1 121 ? -137.793 -136.432 175.176 1.00 71.18 ? 145 TRP C CD2 1 ATOM 967 N NE1 . TRP A 1 121 ? -136.117 -135.859 176.544 1.00 71.31 ? 145 TRP C NE1 1 ATOM 968 C CE2 . TRP A 1 121 ? -136.868 -136.921 176.114 1.00 72.90 ? 145 TRP C CE2 1 ATOM 969 C CE3 . TRP A 1 121 ? -138.684 -137.326 174.585 1.00 72.25 ? 145 TRP C CE3 1 ATOM 970 C CZ2 . TRP A 1 121 ? -136.809 -138.270 176.470 1.00 71.13 ? 145 TRP C CZ2 1 ATOM 971 C CZ3 . TRP A 1 121 ? -138.623 -138.659 174.940 1.00 70.12 ? 145 TRP C CZ3 1 ATOM 972 C CH2 . TRP A 1 121 ? -137.694 -139.118 175.867 1.00 69.16 ? 145 TRP C CH2 1 ATOM 973 N N . THR A 1 122 ? -135.309 -133.261 172.497 1.00 73.60 ? 146 THR C N 1 ATOM 974 C CA . THR A 1 122 ? -134.033 -132.579 172.687 1.00 76.10 ? 146 THR C CA 1 ATOM 975 C C . THR A 1 122 ? -133.918 -131.179 172.095 1.00 75.98 ? 146 THR C C 1 ATOM 976 O O . THR A 1 122 ? -133.347 -130.283 172.724 1.00 75.13 ? 146 THR C O 1 ATOM 977 C CB . THR A 1 122 ? -132.884 -133.384 172.077 1.00 67.78 ? 146 THR C CB 1 ATOM 978 O OG1 . THR A 1 122 ? -132.969 -134.744 172.506 1.00 78.26 ? 146 THR C OG1 1 ATOM 979 C CG2 . THR A 1 122 ? -131.597 -132.807 172.534 1.00 72.56 ? 146 THR C CG2 1 ATOM 980 N N . SER A 1 123 ? -134.464 -130.986 170.897 1.00 76.34 ? 147 SER C N 1 ATOM 981 C CA . SER A 1 123 ? -134.088 -129.832 170.084 1.00 73.55 ? 147 SER C CA 1 ATOM 982 C C . SER A 1 123 ? -135.278 -128.994 169.650 1.00 77.20 ? 147 SER C C 1 ATOM 983 O O . SER A 1 123 ? -136.420 -129.446 169.693 1.00 80.64 ? 147 SER C O 1 ATOM 984 C CB . SER A 1 123 ? -133.303 -130.297 168.861 1.00 74.92 ? 147 SER C CB 1 ATOM 985 O OG . SER A 1 123 ? -132.122 -130.976 169.264 1.00 87.85 ? 147 SER C OG 1 ATOM 986 N N . CYS A 1 124 ? -134.995 -127.760 169.250 1.00 78.56 ? 148 CYS C N 1 ATOM 987 C CA . CYS A 1 124 ? -136.029 -126.789 168.915 1.00 73.79 ? 148 CYS C CA 1 ATOM 988 C C . CYS A 1 124 ? -136.283 -126.593 167.428 1.00 75.24 ? 148 CYS C C 1 ATOM 989 O O . CYS A 1 124 ? -136.908 -125.604 167.039 1.00 77.15 ? 148 CYS C O 1 ATOM 990 C CB . CYS A 1 124 ? -135.672 -125.444 169.517 1.00 72.27 ? 148 CYS C CB 1 ATOM 991 S SG . CYS A 1 124 ? -135.682 -125.486 171.268 1.00 82.75 ? 148 CYS C SG 1 ATOM 992 N N . ASN A 1 125 ? -135.787 -127.499 166.594 1.00 77.48 ? 149 ASN C N 1 ATOM 993 C CA . ASN A 1 125 ? -135.941 -127.344 165.152 1.00 76.34 ? 149 ASN C CA 1 ATOM 994 C C . ASN A 1 125 ? -136.814 -128.428 164.523 1.00 75.60 ? 149 ASN C C 1 ATOM 995 O O . ASN A 1 125 ? -136.514 -128.913 163.433 1.00 75.90 ? 149 ASN C O 1 ATOM 996 C CB . ASN A 1 125 ? -134.571 -127.317 164.473 1.00 76.00 ? 149 ASN C CB 1 ATOM 997 C CG . ASN A 1 125 ? -133.859 -128.655 164.521 1.00 71.88 ? 149 ASN C CG 1 ATOM 998 O OD1 . ASN A 1 125 ? -134.031 -129.439 165.450 1.00 79.44 ? 149 ASN C OD1 1 ATOM 999 N ND2 . ASN A 1 125 ? -133.050 -128.919 163.513 1.00 78.64 ? 149 ASN C ND2 1 ATOM 1000 N N . ASN A 1 126 ? -137.885 -128.808 165.220 1.00 74.35 ? 150 ASN C N 1 ATOM 1001 C CA . ASN A 1 126 ? -138.832 -129.809 164.728 1.00 75.76 ? 150 ASN C CA 1 ATOM 1002 C C . ASN A 1 126 ? -140.134 -129.185 164.240 1.00 76.07 ? 150 ASN C C 1 ATOM 1003 O O . ASN A 1 126 ? -140.406 -128.015 164.507 1.00 77.68 ? 150 ASN C O 1 ATOM 1004 C CB . ASN A 1 126 ? -139.118 -130.834 165.818 1.00 76.85 ? 150 ASN C CB 1 ATOM 1005 C CG . ASN A 1 126 ? -137.854 -131.369 166.442 1.00 80.90 ? 150 ASN C CG 1 ATOM 1006 O OD1 . ASN A 1 126 ? -137.114 -132.138 165.814 1.00 85.94 ? 150 ASN C OD1 1 ATOM 1007 N ND2 . ASN A 1 126 ? -137.583 -130.956 167.678 1.00 74.37 ? 150 ASN C ND2 1 ATOM 1008 N N . ILE A 1 127 ? -140.937 -129.976 163.534 1.00 77.82 ? 151 ILE C N 1 ATOM 1009 C CA . ILE A 1 127 ? -142.134 -129.467 162.878 1.00 74.13 ? 151 ILE C CA 1 ATOM 1010 C C . ILE A 1 127 ? -143.120 -128.886 163.894 1.00 73.40 ? 151 ILE C C 1 ATOM 1011 O O . ILE A 1 127 ? -143.834 -127.927 163.602 1.00 71.39 ? 151 ILE C O 1 ATOM 1012 C CB . ILE A 1 127 ? -142.830 -130.583 162.033 1.00 78.95 ? 151 ILE C CB 1 ATOM 1013 C CG1 . ILE A 1 127 ? -143.951 -129.997 161.186 1.00 89.16 ? 151 ILE C CG1 1 ATOM 1014 C CG2 . ILE A 1 127 ? -143.406 -131.688 162.908 1.00 72.16 ? 151 ILE C CG2 1 ATOM 1015 C CD1 . ILE A 1 127 ? -143.553 -128.728 160.463 1.00 86.20 ? 151 ILE C CD1 1 ATOM 1016 N N . TRP A 1 128 ? -143.128 -129.440 165.101 1.00 73.79 ? 152 TRP C N 1 ATOM 1017 C CA . TRP A 1 128 ? -144.030 -128.965 166.157 1.00 75.23 ? 152 TRP C CA 1 ATOM 1018 C C . TRP A 1 128 ? -143.508 -127.777 166.959 1.00 74.35 ? 152 TRP C C 1 ATOM 1019 O O . TRP A 1 128 ? -144.191 -127.309 167.865 1.00 74.75 ? 152 TRP C O 1 ATOM 1020 C CB . TRP A 1 128 ? -144.339 -130.083 167.144 1.00 69.42 ? 152 TRP C CB 1 ATOM 1021 C CG . TRP A 1 128 ? -143.126 -130.618 167.792 1.00 74.72 ? 152 TRP C CG 1 ATOM 1022 C CD1 . TRP A 1 128 ? -142.466 -130.091 168.865 1.00 73.35 ? 152 TRP C CD1 1 ATOM 1023 C CD2 . TRP A 1 128 ? -142.412 -131.796 167.420 1.00 76.23 ? 152 TRP C CD2 1 ATOM 1024 N NE1 . TRP A 1 128 ? -141.381 -130.870 169.182 1.00 67.68 ? 152 TRP C NE1 1 ATOM 1025 C CE2 . TRP A 1 128 ? -141.326 -131.926 168.310 1.00 73.81 ? 152 TRP C CE2 1 ATOM 1026 C CE3 . TRP A 1 128 ? -142.586 -132.757 166.423 1.00 74.72 ? 152 TRP C CE3 1 ATOM 1027 C CZ2 . TRP A 1 128 ? -140.415 -132.983 168.228 1.00 73.76 ? 152 TRP C CZ2 1 ATOM 1028 C CZ3 . TRP A 1 128 ? -141.684 -133.800 166.345 1.00 77.24 ? 152 TRP C CZ3 1 ATOM 1029 C CH2 . TRP A 1 128 ? -140.612 -133.905 167.241 1.00 72.83 ? 152 TRP C CH2 1 ATOM 1030 N N . ASN A 1 129 ? -142.296 -127.315 166.666 1.00 72.46 ? 153 ASN C N 1 ATOM 1031 C CA . ASN A 1 129 ? -141.687 -126.277 167.484 1.00 69.36 ? 153 ASN C CA 1 ATOM 1032 C C . ASN A 1 129 ? -142.160 -124.884 167.144 1.00 74.07 ? 153 ASN C C 1 ATOM 1033 O O . ASN A 1 129 ? -142.901 -124.646 166.187 1.00 81.58 ? 153 ASN C O 1 ATOM 1034 C CB . ASN A 1 129 ? -140.172 -126.319 167.387 1.00 71.96 ? 153 ASN C CB 1 ATOM 1035 C CG . ASN A 1 129 ? -139.574 -127.469 168.166 1.00 74.12 ? 153 ASN C CG 1 ATOM 1036 O OD1 . ASN A 1 129 ? -138.813 -128.275 167.627 1.00 76.55 ? 153 ASN C OD1 1 ATOM 1037 N ND2 . ASN A 1 129 ? -139.925 -127.558 169.443 1.00 73.37 ? 153 ASN C ND2 1 ATOM 1038 N N . THR A 1 130 ? -141.696 -123.961 167.958 1.00 72.99 ? 154 THR C N 1 ATOM 1039 C CA . THR A 1 130 ? -142.138 -122.589 167.948 1.00 72.97 ? 154 THR C CA 1 ATOM 1040 C C . THR A 1 130 ? -140.896 -121.737 167.791 1.00 72.96 ? 154 THR C C 1 ATOM 1041 O O . THR A 1 130 ? -139.800 -122.167 168.150 1.00 75.84 ? 154 THR C O 1 ATOM 1042 C CB . THR A 1 130 ? -142.894 -122.273 169.260 1.00 76.95 ? 154 THR C CB 1 ATOM 1043 O OG1 . THR A 1 130 ? -144.285 -122.584 169.104 1.00 78.32 ? 154 THR C OG1 1 ATOM 1044 C CG2 . THR A 1 130 ? -142.717 -120.829 169.713 1.00 77.64 ? 154 THR C CG2 1 ATOM 1045 N N . PRO A 1 131 ? -141.043 -120.533 167.241 1.00 73.06 ? 155 PRO C N 1 ATOM 1046 C CA . PRO A 1 131 ? -139.909 -119.616 167.108 1.00 69.84 ? 155 PRO C CA 1 ATOM 1047 C C . PRO A 1 131 ? -139.306 -119.310 168.478 1.00 76.45 ? 155 PRO C C 1 ATOM 1048 O O . PRO A 1 131 ? -138.116 -119.032 168.597 1.00 77.51 ? 155 PRO C O 1 ATOM 1049 C CB . PRO A 1 131 ? -140.533 -118.372 166.490 1.00 70.73 ? 155 PRO C CB 1 ATOM 1050 C CG . PRO A 1 131 ? -141.790 -118.842 165.846 1.00 78.47 ? 155 PRO C CG 1 ATOM 1051 C CD . PRO A 1 131 ? -142.290 -119.960 166.716 1.00 80.22 ? 155 PRO C CD 1 ATOM 1052 N N . ASN A 1 132 ? -140.148 -119.342 169.498 1.00 75.82 ? 156 ASN C N 1 ATOM 1053 C CA . ASN A 1 132 ? -139.755 -119.003 170.860 1.00 73.48 ? 156 ASN C CA 1 ATOM 1054 C C . ASN A 1 132 ? -139.094 -120.127 171.675 1.00 77.58 ? 156 ASN C C 1 ATOM 1055 O O . ASN A 1 132 ? -138.754 -119.918 172.833 1.00 83.84 ? 156 ASN C O 1 ATOM 1056 C CB . ASN A 1 132 ? -140.975 -118.491 171.630 1.00 78.29 ? 156 ASN C CB 1 ATOM 1057 C CG . ASN A 1 132 ? -141.608 -117.253 170.975 1.00 84.90 ? 156 ASN C CG 1 ATOM 1058 O OD1 . ASN A 1 132 ? -141.086 -116.718 169.987 1.00 86.67 ? 156 ASN C OD1 1 ATOM 1059 N ND2 . ASN A 1 132 ? -142.723 -116.786 171.536 1.00 82.43 ? 156 ASN C ND2 1 ATOM 1060 N N . CYS A 1 133 ? -138.933 -121.318 171.107 1.00 78.42 ? 157 CYS C N 1 ATOM 1061 C CA . CYS A 1 133 ? -138.368 -122.450 171.858 1.00 73.35 ? 157 CYS C CA 1 ATOM 1062 C C . CYS A 1 133 ? -136.894 -122.278 172.298 1.00 73.17 ? 157 CYS C C 1 ATOM 1063 O O . CYS A 1 133 ? -136.054 -121.835 171.528 1.00 82.59 ? 157 CYS C O 1 ATOM 1064 C CB . CYS A 1 133 ? -138.522 -123.719 171.017 1.00 75.40 ? 157 CYS C CB 1 ATOM 1065 S SG . CYS A 1 133 ? -137.703 -125.214 171.664 1.00 83.60 ? 157 CYS C SG 1 ATOM 1066 N N . ARG A 1 134 ? -136.598 -122.664 173.536 1.00 70.30 ? 158 ARG C N 1 ATOM 1067 C CA . ARG A 1 134 ? -135.240 -122.663 174.106 1.00 69.23 ? 158 ARG C CA 1 ATOM 1068 C C . ARG A 1 134 ? -134.805 -124.091 174.326 1.00 72.01 ? 158 ARG C C 1 ATOM 1069 O O . ARG A 1 134 ? -135.654 -124.967 174.497 1.00 75.91 ? 158 ARG C O 1 ATOM 1070 C CB . ARG A 1 134 ? -135.179 -121.958 175.459 1.00 67.63 ? 158 ARG C CB 1 ATOM 1071 C CG . ARG A 1 134 ? -135.662 -120.569 175.507 1.00 73.00 ? 158 ARG C CG 1 ATOM 1072 C CD . ARG A 1 134 ? -135.967 -120.215 176.952 1.00 78.97 ? 158 ARG C CD 1 ATOM 1073 N NE . ARG A 1 134 ? -135.031 -120.796 177.917 1.00 74.79 ? 158 ARG C NE 1 ATOM 1074 C CZ . ARG A 1 134 ? -134.128 -120.101 178.612 1.00 75.43 ? 158 ARG C CZ 1 ATOM 1075 N NH1 . ARG A 1 134 ? -134.009 -118.785 178.440 1.00 84.56 ? 158 ARG C NH1 1 ATOM 1076 N NH2 . ARG A 1 134 ? -133.333 -120.730 179.477 1.00 68.53 ? 158 ARG C NH2 1 ATOM 1077 N N . PRO A 1 135 ? -133.484 -124.330 174.350 1.00 70.32 ? 159 PRO C N 1 ATOM 1078 C CA . PRO A 1 135 ? -133.026 -125.668 174.730 1.00 71.18 ? 159 PRO C CA 1 ATOM 1079 C C . PRO A 1 135 ? -133.461 -126.110 176.145 1.00 64.60 ? 159 PRO C C 1 ATOM 1080 O O . PRO A 1 135 ? -133.755 -127.287 176.291 1.00 73.09 ? 159 PRO C O 1 ATOM 1081 C CB . PRO A 1 135 ? -131.492 -125.552 174.634 1.00 64.28 ? 159 PRO C CB 1 ATOM 1082 C CG . PRO A 1 135 ? -131.194 -124.116 174.470 1.00 61.33 ? 159 PRO C CG 1 ATOM 1083 C CD . PRO A 1 135 ? -132.386 -123.481 173.867 1.00 66.18 ? 159 PRO C CD 1 ATOM 1084 N N . PHE A 1 136 ? -133.564 -125.223 177.132 1.00 66.86 ? 160 PHE C N 1 ATOM 1085 C CA . PHE A 1 136 ? -133.950 -125.670 178.484 1.00 68.15 ? 160 PHE C CA 1 ATOM 1086 C C . PHE A 1 136 ? -134.845 -124.681 179.240 1.00 68.32 ? 160 PHE C C 1 ATOM 1087 O O . PHE A 1 136 ? -135.069 -123.568 178.770 1.00 72.53 ? 160 PHE C O 1 ATOM 1088 C CB . PHE A 1 136 ? -132.703 -125.976 179.316 1.00 63.89 ? 160 PHE C CB 1 ATOM 1089 C CG . PHE A 1 136 ? -131.822 -127.032 178.716 1.00 73.07 ? 160 PHE C CG 1 ATOM 1090 C CD1 . PHE A 1 136 ? -132.106 -128.381 178.898 1.00 69.34 ? 160 PHE C CD1 1 ATOM 1091 C CD2 . PHE A 1 136 ? -130.715 -126.682 177.956 1.00 73.02 ? 160 PHE C CD2 1 ATOM 1092 C CE1 . PHE A 1 136 ? -131.301 -129.353 178.343 1.00 67.68 ? 160 PHE C CE1 1 ATOM 1093 C CE2 . PHE A 1 136 ? -129.914 -127.654 177.399 1.00 74.16 ? 160 PHE C CE2 1 ATOM 1094 C CZ . PHE A 1 136 ? -130.206 -128.986 177.595 1.00 71.32 ? 160 PHE C CZ 1 ATOM 1095 N N . GLU A 1 137 ? -135.374 -125.110 180.385 1.00 65.92 ? 161 GLU C N 1 ATOM 1096 C CA . GLU A 1 137 ? -136.309 -124.303 181.170 1.00 68.15 ? 161 GLU C CA 1 ATOM 1097 C C . GLU A 1 137 ? -135.842 -122.879 181.381 1.00 68.39 ? 161 GLU C C 1 ATOM 1098 O O . GLU A 1 137 ? -134.695 -122.654 181.730 1.00 73.44 ? 161 GLU C O 1 ATOM 1099 C CB . GLU A 1 137 ? -136.559 -124.940 182.543 1.00 71.13 ? 161 GLU C CB 1 ATOM 1100 C CG . GLU A 1 137 ? -137.208 -126.309 182.501 1.00 71.72 ? 161 GLU C CG 1 ATOM 1101 C CD . GLU A 1 137 ? -138.429 -126.345 181.603 1.00 80.14 ? 161 GLU C CD 1 ATOM 1102 O OE1 . GLU A 1 137 ? -139.283 -125.435 181.703 1.00 88.13 ? 161 GLU C OE1 1 ATOM 1103 O OE2 . GLU A 1 137 ? -138.522 -127.278 180.777 1.00 80.79 ? 161 GLU C OE2 1 ATOM 1104 N N . GLY A 1 138 ? -136.737 -121.918 181.174 1.00 70.75 ? 203 GLY C N 1 ATOM 1105 C CA . GLY A 1 138 ? -136.442 -120.529 181.484 1.00 70.48 ? 203 GLY C CA 1 ATOM 1106 C C . GLY A 1 138 ? -137.393 -119.993 182.538 1.00 71.88 ? 203 GLY C C 1 ATOM 1107 O O . GLY A 1 138 ? -138.038 -120.767 183.237 1.00 76.69 ? 203 GLY C O 1 ATOM 1108 N N . HIS A 1 139 ? -137.508 -118.676 182.664 1.00 81.48 ? 204 HIS C N 1 ATOM 1109 C CA . HIS A 1 139 ? -138.478 -118.123 183.612 1.00 83.28 ? 204 HIS C CA 1 ATOM 1110 C C . HIS A 1 139 ? -139.438 -117.118 182.968 1.00 78.38 ? 204 HIS C C 1 ATOM 1111 O O . HIS A 1 139 ? -140.059 -116.313 183.658 1.00 87.15 ? 204 HIS C O 1 ATOM 1112 C CB . HIS A 1 139 ? -137.759 -117.485 184.813 1.00 80.87 ? 204 HIS C CB 1 ATOM 1113 C CG . HIS A 1 139 ? -136.666 -116.535 184.441 1.00 84.39 ? 204 HIS C CG 1 ATOM 1114 N ND1 . HIS A 1 139 ? -135.342 -116.914 184.367 1.00 90.45 ? 204 HIS C ND1 1 ATOM 1115 C CD2 . HIS A 1 139 ? -136.696 -115.215 184.137 1.00 94.83 ? 204 HIS C CD2 1 ATOM 1116 C CE1 . HIS A 1 139 ? -134.606 -115.873 184.022 1.00 99.11 ? 204 HIS C CE1 1 ATOM 1117 N NE2 . HIS A 1 139 ? -135.404 -114.830 183.872 1.00 101.65 ? 204 HIS C NE2 1 ATOM 1118 N N . VAL A 1 140 ? -139.561 -117.173 181.647 1.00 80.01 ? 205 VAL C N 1 ATOM 1119 C CA . VAL A 1 140 ? -140.505 -116.316 180.923 1.00 83.71 ? 205 VAL C CA 1 ATOM 1120 C C . VAL A 1 140 ? -141.548 -117.176 180.202 1.00 83.58 ? 205 VAL C C 1 ATOM 1121 O O . VAL A 1 140 ? -141.187 -118.048 179.405 1.00 83.41 ? 205 VAL C O 1 ATOM 1122 C CB . VAL A 1 140 ? -139.777 -115.407 179.920 1.00 78.95 ? 205 VAL C CB 1 ATOM 1123 C CG1 . VAL A 1 140 ? -140.765 -114.662 179.054 1.00 79.19 ? 205 VAL C CG1 1 ATOM 1124 C CG2 . VAL A 1 140 ? -138.880 -114.441 180.665 1.00 81.54 ? 205 VAL C CG2 1 ATOM 1125 N N . GLU A 1 141 ? -142.833 -116.931 180.475 1.00 80.76 ? 206 GLU C N 1 ATOM 1126 C CA . GLU A 1 141 ? -143.873 -117.901 180.115 1.00 82.66 ? 206 GLU C CA 1 ATOM 1127 C C . GLU A 1 141 ? -143.996 -118.136 178.616 1.00 81.20 ? 206 GLU C C 1 ATOM 1128 O O . GLU A 1 141 ? -144.353 -119.222 178.176 1.00 88.94 ? 206 GLU C O 1 ATOM 1129 C CB . GLU A 1 141 ? -145.238 -117.477 180.668 1.00 89.07 ? 206 GLU C CB 1 ATOM 1130 C CG . GLU A 1 141 ? -146.365 -118.448 180.282 1.00 97.36 ? 206 GLU C CG 1 ATOM 1131 C CD . GLU A 1 141 ? -147.671 -118.173 181.011 1.00 108.50 ? 206 GLU C CD 1 ATOM 1132 O OE1 . GLU A 1 141 ? -147.820 -117.056 181.558 1.00 116.07 ? 206 GLU C OE1 1 ATOM 1133 O OE2 . GLU A 1 141 ? -148.544 -119.074 181.047 1.00 103.15 ? 206 GLU C OE2 1 ATOM 1134 N N . GLY A 1 142 ? -143.670 -117.136 177.822 1.00 78.68 ? 207 GLY C N 1 ATOM 1135 C CA . GLY A 1 142 ? -143.886 -117.259 176.401 1.00 79.77 ? 207 GLY C CA 1 ATOM 1136 C C . GLY A 1 142 ? -142.771 -117.994 175.706 1.00 74.50 ? 207 GLY C C 1 ATOM 1137 O O . GLY A 1 142 ? -142.818 -118.175 174.494 1.00 75.71 ? 207 GLY C O 1 ATOM 1138 N N . PHE A 1 143 ? -141.768 -118.425 176.467 1.00 79.60 ? 208 PHE C N 1 ATOM 1139 C CA . PHE A 1 143 ? -140.623 -119.109 175.870 1.00 79.18 ? 208 PHE C CA 1 ATOM 1140 C C . PHE A 1 143 ? -140.337 -120.456 176.516 1.00 72.18 ? 208 PHE C C 1 ATOM 1141 O O . PHE A 1 143 ? -139.493 -120.576 177.392 1.00 72.52 ? 208 PHE C O 1 ATOM 1142 C CB . PHE A 1 143 ? -139.386 -118.213 175.930 1.00 78.38 ? 208 PHE C CB 1 ATOM 1143 C CG . PHE A 1 143 ? -139.555 -116.917 175.190 1.00 83.95 ? 208 PHE C CG 1 ATOM 1144 C CD1 . PHE A 1 143 ? -139.106 -116.786 173.880 1.00 80.33 ? 208 PHE C CD1 1 ATOM 1145 C CD2 . PHE A 1 143 ? -140.195 -115.837 175.794 1.00 79.84 ? 208 PHE C CD2 1 ATOM 1146 C CE1 . PHE A 1 143 ? -139.275 -115.597 173.190 1.00 76.18 ? 208 PHE C CE1 1 ATOM 1147 C CE2 . PHE A 1 143 ? -140.362 -114.642 175.113 1.00 77.99 ? 208 PHE C CE2 1 ATOM 1148 C CZ . PHE A 1 143 ? -139.901 -114.521 173.812 1.00 75.50 ? 208 PHE C CZ 1 ATOM 1149 N N . GLN A 1 144 ? -141.051 -121.468 176.043 1.00 77.96 ? 209 GLN C N 1 ATOM 1150 C CA . GLN A 1 144 ? -140.880 -122.830 176.511 1.00 71.87 ? 209 GLN C CA 1 ATOM 1151 C C . GLN A 1 144 ? -139.579 -123.509 176.064 1.00 69.46 ? 209 GLN C C 1 ATOM 1152 O O . GLN A 1 144 ? -138.970 -123.165 175.057 1.00 75.83 ? 209 GLN C O 1 ATOM 1153 C CB . GLN A 1 144 ? -142.074 -123.670 176.062 1.00 73.02 ? 209 GLN C CB 1 ATOM 1154 C CG . GLN A 1 144 ? -143.358 -123.213 176.689 1.00 67.77 ? 209 GLN C CG 1 ATOM 1155 C CD . GLN A 1 144 ? -143.194 -122.929 178.162 1.00 71.18 ? 209 GLN C CD 1 ATOM 1156 O OE1 . GLN A 1 144 ? -142.854 -123.821 178.945 1.00 73.97 ? 209 GLN C OE1 1 ATOM 1157 N NE2 . GLN A 1 144 ? -143.420 -121.677 178.553 1.00 74.28 ? 209 GLN C NE2 1 ATOM 1158 N N . SER A 1 145 ? -139.176 -124.482 176.863 1.00 72.97 ? 210 SER C N 1 ATOM 1159 C CA . SER A 1 145 ? -138.072 -125.375 176.590 1.00 65.11 ? 210 SER C CA 1 ATOM 1160 C C . SER A 1 145 ? -138.414 -126.380 175.502 1.00 73.32 ? 210 SER C C 1 ATOM 1161 O O . SER A 1 145 ? -139.589 -126.669 175.245 1.00 75.24 ? 210 SER C O 1 ATOM 1162 C CB . SER A 1 145 ? -137.702 -126.128 177.853 1.00 72.51 ? 210 SER C CB 1 ATOM 1163 O OG . SER A 1 145 ? -138.787 -126.916 178.291 1.00 72.68 ? 210 SER C OG 1 ATOM 1164 N N . ALA A 1 146 ? -137.386 -126.946 174.885 1.00 73.90 ? 211 ALA C N 1 ATOM 1165 C CA . ALA A 1 146 ? -137.595 -127.931 173.847 1.00 69.57 ? 211 ALA C CA 1 ATOM 1166 C C . ALA A 1 146 ? -138.422 -129.113 174.355 1.00 74.71 ? 211 ALA C C 1 ATOM 1167 O O . ALA A 1 146 ? -139.271 -129.629 173.628 1.00 79.08 ? 211 ALA C O 1 ATOM 1168 C CB . ALA A 1 146 ? -136.256 -128.417 173.315 1.00 66.41 ? 211 ALA C CB 1 ATOM 1169 N N . ALA A 1 147 ? -138.189 -129.530 175.599 1.00 77.49 ? 212 ALA C N 1 ATOM 1170 C CA . ALA A 1 147 ? -138.966 -130.624 176.183 1.00 73.52 ? 212 ALA C CA 1 ATOM 1171 C C . ALA A 1 147 ? -140.402 -130.216 176.494 1.00 72.40 ? 212 ALA C C 1 ATOM 1172 O O . ALA A 1 147 ? -141.319 -131.044 176.456 1.00 71.16 ? 212 ALA C O 1 ATOM 1173 C CB . ALA A 1 147 ? -138.296 -131.144 177.439 1.00 68.48 ? 212 ALA C CB 1 ATOM 1174 N N . SER A 1 148 ? -140.601 -128.948 176.832 1.00 75.28 ? 213 SER C N 1 ATOM 1175 C CA . SER A 1 148 ? -141.948 -128.481 177.129 1.00 72.29 ? 213 SER C CA 1 ATOM 1176 C C . SER A 1 148 ? -142.816 -128.442 175.870 1.00 72.91 ? 213 SER C C 1 ATOM 1177 O O . SER A 1 148 ? -143.988 -128.822 175.908 1.00 69.20 ? 213 SER C O 1 ATOM 1178 C CB . SER A 1 148 ? -141.913 -127.100 177.769 1.00 68.59 ? 213 SER C CB 1 ATOM 1179 O OG . SER A 1 148 ? -143.226 -126.590 177.905 1.00 73.14 ? 213 SER C OG 1 ATOM 1180 N N . GLU A 1 149 ? -142.242 -127.974 174.759 1.00 72.52 ? 214 GLU C N 1 ATOM 1181 C CA . GLU A 1 149 ? -142.970 -127.924 173.493 1.00 67.03 ? 214 GLU C CA 1 ATOM 1182 C C . GLU A 1 149 ? -143.230 -129.321 172.935 1.00 70.93 ? 214 GLU C C 1 ATOM 1183 O O . GLU A 1 149 ? -144.250 -129.553 172.282 1.00 73.71 ? 214 GLU C O 1 ATOM 1184 C CB . GLU A 1 149 ? -142.220 -127.076 172.460 1.00 71.50 ? 214 GLU C CB 1 ATOM 1185 C CG . GLU A 1 149 ? -142.078 -125.597 172.848 1.00 72.01 ? 214 GLU C CG 1 ATOM 1186 C CD . GLU A 1 149 ? -141.705 -124.682 171.680 1.00 73.23 ? 214 GLU C CD 1 ATOM 1187 O OE1 . GLU A 1 149 ? -141.144 -125.166 170.671 1.00 70.52 ? 214 GLU C OE1 1 ATOM 1188 O OE2 . GLU A 1 149 ? -141.978 -123.464 171.777 1.00 81.97 ? 214 GLU C OE2 1 ATOM 1189 N N . TYR A 1 150 ? -142.325 -130.261 173.193 1.00 70.72 ? 215 TYR C N 1 ATOM 1190 C CA . TYR A 1 150 ? -142.576 -131.628 172.763 1.00 69.29 ? 215 TYR C CA 1 ATOM 1191 C C . TYR A 1 150 ? -143.781 -132.180 173.483 1.00 68.73 ? 215 TYR C C 1 ATOM 1192 O O . TYR A 1 150 ? -144.675 -132.750 172.864 1.00 71.72 ? 215 TYR C O 1 ATOM 1193 C CB . TYR A 1 150 ? -141.385 -132.538 173.024 1.00 67.08 ? 215 TYR C CB 1 ATOM 1194 C CG . TYR A 1 150 ? -141.620 -133.968 172.580 1.00 69.22 ? 215 TYR C CG 1 ATOM 1195 C CD1 . TYR A 1 150 ? -141.469 -134.333 171.252 1.00 72.87 ? 215 TYR C CD1 1 ATOM 1196 C CD2 . TYR A 1 150 ? -141.983 -134.954 173.488 1.00 72.27 ? 215 TYR C CD2 1 ATOM 1197 C CE1 . TYR A 1 150 ? -141.673 -135.635 170.841 1.00 77.31 ? 215 TYR C CE1 1 ATOM 1198 C CE2 . TYR A 1 150 ? -142.196 -136.267 173.087 1.00 72.08 ? 215 TYR C CE2 1 ATOM 1199 C CZ . TYR A 1 150 ? -142.033 -136.604 171.763 1.00 78.38 ? 215 TYR C CZ 1 ATOM 1200 O OH . TYR A 1 150 ? -142.235 -137.904 171.347 1.00 82.22 ? 215 TYR C OH 1 ATOM 1201 N N . PHE A 1 151 ? -143.808 -132.005 174.798 1.00 67.33 ? 216 PHE C N 1 ATOM 1202 C CA . PHE A 1 151 ? -144.886 -132.572 175.576 1.00 65.54 ? 216 PHE C CA 1 ATOM 1203 C C . PHE A 1 151 ? -146.173 -131.904 175.158 1.00 70.73 ? 216 PHE C C 1 ATOM 1204 O O . PHE A 1 151 ? -147.179 -132.550 174.835 1.00 69.42 ? 216 PHE C O 1 ATOM 1205 C CB . PHE A 1 151 ? -144.652 -132.375 177.060 1.00 60.47 ? 216 PHE C CB 1 ATOM 1206 C CG . PHE A 1 151 ? -145.708 -132.983 177.912 1.00 61.89 ? 216 PHE C CG 1 ATOM 1207 C CD1 . PHE A 1 151 ? -146.220 -134.238 177.601 1.00 67.09 ? 216 PHE C CD1 1 ATOM 1208 C CD2 . PHE A 1 151 ? -146.190 -132.319 179.028 1.00 59.31 ? 216 PHE C CD2 1 ATOM 1209 C CE1 . PHE A 1 151 ? -147.208 -134.815 178.379 1.00 63.82 ? 216 PHE C CE1 1 ATOM 1210 C CE2 . PHE A 1 151 ? -147.173 -132.888 179.812 1.00 65.03 ? 216 PHE C CE2 1 ATOM 1211 C CZ . PHE A 1 151 ? -147.682 -134.142 179.491 1.00 66.19 ? 216 PHE C CZ 1 ATOM 1212 N N . ASN A 1 152 ? -146.107 -130.585 175.117 1.00 72.19 ? 217 ASN C N 1 ATOM 1213 C CA . ASN A 1 152 ? -147.292 -129.788 174.945 1.00 69.44 ? 217 ASN C CA 1 ATOM 1214 C C . ASN A 1 152 ? -147.799 -129.762 173.523 1.00 71.03 ? 217 ASN C C 1 ATOM 1215 O O . ASN A 1 152 ? -148.994 -129.891 173.296 1.00 71.91 ? 217 ASN C O 1 ATOM 1216 C CB . ASN A 1 152 ? -147.014 -128.380 175.410 1.00 76.70 ? 217 ASN C CB 1 ATOM 1217 C CG . ASN A 1 152 ? -148.264 -127.627 175.686 1.00 84.36 ? 217 ASN C CG 1 ATOM 1218 O OD1 . ASN A 1 152 ? -148.868 -127.055 174.769 1.00 73.67 ? 217 ASN C OD1 1 ATOM 1219 N ND2 . ASN A 1 152 ? -148.684 -127.621 176.961 1.00 89.82 ? 217 ASN C ND2 1 ATOM 1220 N N . ARG A 1 153 ? -146.891 -129.597 172.566 1.00 75.32 ? 218 ARG C N 1 ATOM 1221 C CA . ARG A 1 153 ? -147.285 -129.416 171.167 1.00 78.37 ? 218 ARG C CA 1 ATOM 1222 C C . ARG A 1 153 ? -147.259 -130.698 170.337 1.00 74.11 ? 218 ARG C C 1 ATOM 1223 O O . ARG A 1 153 ? -147.881 -130.761 169.283 1.00 76.47 ? 218 ARG C O 1 ATOM 1224 C CB . ARG A 1 153 ? -146.391 -128.353 170.499 1.00 71.13 ? 218 ARG C CB 1 ATOM 1225 C CG . ARG A 1 153 ? -146.448 -126.995 171.140 1.00 62.99 ? 218 ARG C CG 1 ATOM 1226 C CD . ARG A 1 153 ? -145.601 -126.000 170.398 1.00 68.33 ? 218 ARG C CD 1 ATOM 1227 N NE . ARG A 1 153 ? -146.142 -125.725 169.071 1.00 74.28 ? 218 ARG C NE 1 ATOM 1228 C CZ . ARG A 1 153 ? -147.051 -124.790 168.807 1.00 77.37 ? 218 ARG C CZ 1 ATOM 1229 N NH1 . ARG A 1 153 ? -147.525 -124.028 169.791 1.00 74.50 ? 218 ARG C NH1 1 ATOM 1230 N NH2 . ARG A 1 153 ? -147.492 -124.620 167.560 1.00 75.06 ? 218 ARG C NH2 1 ATOM 1231 N N . TYR A 1 154 ? -146.518 -131.704 170.786 1.00 71.50 ? 219 TYR C N 1 ATOM 1232 C CA . TYR A 1 154 ? -146.487 -132.976 170.067 1.00 70.54 ? 219 TYR C CA 1 ATOM 1233 C C . TYR A 1 154 ? -147.265 -134.109 170.751 1.00 76.15 ? 219 TYR C C 1 ATOM 1234 O O . TYR A 1 154 ? -148.103 -134.747 170.125 1.00 79.49 ? 219 TYR C O 1 ATOM 1235 C CB . TYR A 1 154 ? -145.054 -133.451 169.844 1.00 70.27 ? 219 TYR C CB 1 ATOM 1236 C CG . TYR A 1 154 ? -144.997 -134.755 169.080 1.00 78.36 ? 219 TYR C CG 1 ATOM 1237 C CD1 . TYR A 1 154 ? -145.086 -134.767 167.692 1.00 82.00 ? 219 TYR C CD1 1 ATOM 1238 C CD2 . TYR A 1 154 ? -144.885 -135.972 169.739 1.00 77.30 ? 219 TYR C CD2 1 ATOM 1239 C CE1 . TYR A 1 154 ? -145.050 -135.954 166.972 1.00 82.10 ? 219 TYR C CE1 1 ATOM 1240 C CE2 . TYR A 1 154 ? -144.853 -137.176 169.030 1.00 84.77 ? 219 TYR C CE2 1 ATOM 1241 C CZ . TYR A 1 154 ? -144.933 -137.156 167.646 1.00 89.32 ? 219 TYR C CZ 1 ATOM 1242 O OH . TYR A 1 154 ? -144.889 -138.333 166.938 1.00 92.75 ? 219 TYR C OH 1 ATOM 1243 N N . ILE A 1 155 ? -146.960 -134.388 172.018 1.00 74.35 ? 220 ILE C N 1 ATOM 1244 C CA . ILE A 1 155 ? -147.638 -135.454 172.746 1.00 72.64 ? 220 ILE C CA 1 ATOM 1245 C C . ILE A 1 155 ? -149.094 -135.088 173.022 1.00 73.93 ? 220 ILE C C 1 ATOM 1246 O O . ILE A 1 155 ? -150.004 -135.846 172.727 1.00 79.42 ? 220 ILE C O 1 ATOM 1247 C CB . ILE A 1 155 ? -146.938 -135.757 174.098 1.00 70.73 ? 220 ILE C CB 1 ATOM 1248 C CG1 . ILE A 1 155 ? -145.482 -136.168 173.883 1.00 69.39 ? 220 ILE C CG1 1 ATOM 1249 C CG2 . ILE A 1 155 ? -147.686 -136.831 174.871 1.00 70.50 ? 220 ILE C CG2 1 ATOM 1250 C CD1 . ILE A 1 155 ? -145.303 -137.453 173.112 1.00 73.74 ? 220 ILE C CD1 1 ATOM 1251 N N . LEU A 1 156 ? -149.307 -133.910 173.585 1.00 71.11 ? 221 LEU C N 1 ATOM 1252 C CA . LEU A 1 156 ? -150.635 -133.484 174.000 1.00 66.99 ? 221 LEU C CA 1 ATOM 1253 C C . LEU A 1 156 ? -151.443 -132.779 172.891 1.00 76.43 ? 221 LEU C C 1 ATOM 1254 O O . LEU A 1 156 ? -152.668 -132.889 172.848 1.00 81.78 ? 221 LEU C O 1 ATOM 1255 C CB . LEU A 1 156 ? -150.507 -132.554 175.207 1.00 67.47 ? 221 LEU C CB 1 ATOM 1256 C CG . LEU A 1 156 ? -150.747 -133.094 176.615 1.00 67.62 ? 221 LEU C CG 1 ATOM 1257 C CD1 . LEU A 1 156 ? -150.226 -134.508 176.783 1.00 71.45 ? 221 LEU C CD1 1 ATOM 1258 C CD2 . LEU A 1 156 ? -150.115 -132.140 177.636 1.00 66.91 ? 221 LEU C CD2 1 ATOM 1259 N N . GLU A 1 157 ? -150.750 -132.055 172.009 1.00 78.14 ? 222 GLU C N 1 ATOM 1260 C CA . GLU A 1 157 ? -151.365 -131.102 171.072 1.00 76.72 ? 222 GLU C CA 1 ATOM 1261 C C . GLU A 1 157 ? -152.305 -130.129 171.797 1.00 73.53 ? 222 GLU C C 1 ATOM 1262 O O . GLU A 1 157 ? -153.285 -129.659 171.233 1.00 73.57 ? 222 GLU C O 1 ATOM 1263 C CB . GLU A 1 157 ? -152.106 -131.833 169.944 1.00 73.74 ? 222 GLU C CB 1 ATOM 1264 C CG . GLU A 1 157 ? -151.198 -132.707 169.087 1.00 82.79 ? 222 GLU C CG 1 ATOM 1265 C CD . GLU A 1 157 ? -151.893 -133.300 167.862 1.00 91.67 ? 222 GLU C CD 1 ATOM 1266 O OE1 . GLU A 1 157 ? -153.053 -132.912 167.576 1.00 88.76 ? 222 GLU C OE1 1 ATOM 1267 O OE2 . GLU A 1 157 ? -151.276 -134.160 167.182 1.00 94.50 ? 222 GLU C OE2 1 ATOM 1268 N N . LEU A 1 158 ? -151.962 -129.787 173.033 1.00 72.03 ? 223 LEU C N 1 ATOM 1269 C CA . LEU A 1 158 ? -152.803 -128.919 173.852 1.00 73.64 ? 223 LEU C CA 1 ATOM 1270 C C . LEU A 1 158 ? -152.936 -127.513 173.262 1.00 74.31 ? 223 LEU C C 1 ATOM 1271 O O . LEU A 1 158 ? -153.862 -126.783 173.604 1.00 77.84 ? 223 LEU C O 1 ATOM 1272 C CB . LEU A 1 158 ? -152.253 -128.838 175.279 1.00 71.45 ? 223 LEU C CB 1 ATOM 1273 C CG . LEU A 1 158 ? -153.115 -128.175 176.361 1.00 71.78 ? 223 LEU C CG 1 ATOM 1274 C CD1 . LEU A 1 158 ? -154.496 -128.797 176.429 1.00 70.36 ? 223 LEU C CD1 1 ATOM 1275 C CD2 . LEU A 1 158 ? -152.433 -128.256 177.718 1.00 69.46 ? 223 LEU C CD2 1 ATOM 1276 N N . ASN A 1 159 ? -151.998 -127.115 172.408 1.00 71.91 ? 224 ASN C N 1 ATOM 1277 C CA . ASN A 1 159 ? -152.043 -125.784 171.816 1.00 74.00 ? 224 ASN C CA 1 ATOM 1278 C C . ASN A 1 159 ? -153.259 -125.595 170.904 1.00 79.21 ? 224 ASN C C 1 ATOM 1279 O O . ASN A 1 159 ? -153.719 -124.473 170.675 1.00 86.03 ? 224 ASN C O 1 ATOM 1280 C CB . ASN A 1 159 ? -150.764 -125.499 171.036 1.00 74.49 ? 224 ASN C CB 1 ATOM 1281 C CG . ASN A 1 159 ? -150.447 -126.569 170.018 1.00 73.02 ? 224 ASN C CG 1 ATOM 1282 O OD1 . ASN A 1 159 ? -151.321 -127.271 169.563 1.00 84.55 ? 224 ASN C OD1 1 ATOM 1283 N ND2 . ASN A 1 159 ? -149.189 -126.695 169.662 1.00 78.96 ? 224 ASN C ND2 1 ATOM 1284 N N . ARG A 1 160 ? -153.769 -126.702 170.381 1.00 75.48 ? 225 ARG C N 1 ATOM 1285 C CA . ARG A 1 160 ? -154.869 -126.688 169.427 1.00 78.78 ? 225 ARG C CA 1 ATOM 1286 C C . ARG A 1 160 ? -156.239 -126.624 170.088 1.00 80.33 ? 225 ARG C C 1 ATOM 1287 O O . ARG A 1 160 ? -157.254 -126.636 169.398 1.00 85.16 ? 225 ARG C O 1 ATOM 1288 C CB . ARG A 1 160 ? -154.791 -127.922 168.528 1.00 76.18 ? 225 ARG C CB 1 ATOM 1289 C CG . ARG A 1 160 ? -153.461 -128.068 167.845 1.00 73.00 ? 225 ARG C CG 1 ATOM 1290 C CD . ARG A 1 160 ? -153.438 -129.218 166.901 1.00 79.72 ? 225 ARG C CD 1 ATOM 1291 N NE . ARG A 1 160 ? -152.080 -129.524 166.471 1.00 80.13 ? 225 ARG C NE 1 ATOM 1292 C CZ . ARG A 1 160 ? -151.787 -130.390 165.510 1.00 82.63 ? 225 ARG C CZ 1 ATOM 1293 N NH1 . ARG A 1 160 ? -152.762 -131.026 164.879 1.00 88.20 ? 225 ARG C NH1 1 ATOM 1294 N NH2 . ARG A 1 160 ? -150.525 -130.617 165.184 1.00 86.68 ? 225 ARG C NH2 1 ATOM 1295 N N . SER A 1 161 ? -156.264 -126.616 171.417 1.00 76.52 ? 226 SER C N 1 ATOM 1296 C CA . SER A 1 161 ? -157.512 -126.514 172.161 1.00 80.20 ? 226 SER C CA 1 ATOM 1297 C C . SER A 1 161 ? -157.641 -125.143 172.804 1.00 84.09 ? 226 SER C C 1 ATOM 1298 O O . SER A 1 161 ? -156.681 -124.639 173.396 1.00 87.79 ? 226 SER C O 1 ATOM 1299 C CB . SER A 1 161 ? -157.600 -127.611 173.234 1.00 82.90 ? 226 SER C CB 1 ATOM 1300 O OG . SER A 1 161 ? -158.537 -127.254 174.250 1.00 83.52 ? 226 SER C OG 1 ATOM 1301 N N . GLU A 1 162 ? -158.820 -124.537 172.682 1.00 86.68 ? 227 GLU C N 1 ATOM 1302 C CA . GLU A 1 162 ? -159.053 -123.213 173.252 1.00 83.82 ? 227 GLU C CA 1 ATOM 1303 C C . GLU A 1 162 ? -159.618 -123.267 174.662 1.00 86.25 ? 227 GLU C C 1 ATOM 1304 O O . GLU A 1 162 ? -159.897 -122.226 175.261 1.00 94.01 ? 227 GLU C O 1 ATOM 1305 C CB . GLU A 1 162 ? -159.991 -122.410 172.368 1.00 86.41 ? 227 GLU C CB 1 ATOM 1306 C CG . GLU A 1 162 ? -159.556 -122.337 170.925 1.00 92.63 ? 227 GLU C CG 1 ATOM 1307 C CD . GLU A 1 162 ? -160.328 -121.295 170.142 1.00 103.77 ? 227 GLU C CD 1 ATOM 1308 O OE1 . GLU A 1 162 ? -161.461 -120.939 170.551 1.00 105.57 ? 227 GLU C OE1 1 ATOM 1309 O OE2 . GLU A 1 162 ? -159.789 -120.823 169.118 1.00 107.63 ? 227 GLU C OE2 1 ATOM 1310 N N . GLY A 1 163 ? -159.808 -124.478 175.180 1.00 82.75 ? 228 GLY C N 1 ATOM 1311 C CA . GLY A 1 163 ? -160.338 -124.660 176.521 1.00 83.56 ? 228 GLY C CA 1 ATOM 1312 C C . GLY A 1 163 ? -161.063 -125.986 176.696 1.00 86.25 ? 228 GLY C C 1 ATOM 1313 O O . GLY A 1 163 ? -160.993 -126.862 175.823 1.00 78.92 ? 228 GLY C O 1 ATOM 1314 N N . ILE A 1 164 ? -161.749 -126.137 177.827 1.00 79.92 ? 229 ILE C N 1 ATOM 1315 C CA . ILE A 1 164 ? -162.458 -127.372 178.118 1.00 82.38 ? 229 ILE C CA 1 ATOM 1316 C C . ILE A 1 164 ? -163.669 -127.523 177.222 1.00 85.52 ? 229 ILE C C 1 ATOM 1317 O O . ILE A 1 164 ? -164.203 -128.622 177.063 1.00 80.90 ? 229 ILE C O 1 ATOM 1318 C CB . ILE A 1 164 ? -162.917 -127.450 179.575 1.00 89.19 ? 229 ILE C CB 1 ATOM 1319 C CG1 . ILE A 1 164 ? -163.493 -128.845 179.857 1.00 85.06 ? 229 ILE C CG1 1 ATOM 1320 C CG2 . ILE A 1 164 ? -163.917 -126.355 179.872 1.00 86.01 ? 229 ILE C CG2 1 ATOM 1321 C CD1 . ILE A 1 164 ? -163.255 -129.352 181.261 1.00 85.23 ? 229 ILE C CD1 1 ATOM 1322 N N . HIS A 1 165 ? -164.102 -126.407 176.644 1.00 89.39 ? 230 HIS C N 1 ATOM 1323 C CA . HIS A 1 165 ? -165.225 -126.398 175.709 1.00 88.06 ? 230 HIS C CA 1 ATOM 1324 C C . HIS A 1 165 ? -164.799 -126.873 174.327 1.00 81.84 ? 230 HIS C C 1 ATOM 1325 O O . HIS A 1 165 ? -165.628 -127.104 173.456 1.00 84.35 ? 230 HIS C O 1 ATOM 1326 C CB . HIS A 1 165 ? -165.814 -124.994 175.614 1.00 92.86 ? 230 HIS C CB 1 ATOM 1327 C CG . HIS A 1 165 ? -164.827 -123.972 175.154 1.00 91.10 ? 230 HIS C CG 1 ATOM 1328 N ND1 . HIS A 1 165 ? -164.513 -123.795 173.823 1.00 87.64 ? 230 HIS C ND1 1 ATOM 1329 C CD2 . HIS A 1 165 ? -164.054 -123.101 175.845 1.00 91.52 ? 230 HIS C CD2 1 ATOM 1330 C CE1 . HIS A 1 165 ? -163.606 -122.842 173.711 1.00 93.57 ? 230 HIS C CE1 1 ATOM 1331 N NE2 . HIS A 1 165 ? -163.308 -122.407 174.924 1.00 99.59 ? 230 HIS C NE2 1 ATOM 1332 N N . ASP A 1 166 ? -163.494 -127.008 174.135 1.00 84.20 ? 231 ASP C N 1 ATOM 1333 C CA . ASP A 1 166 ? -162.929 -127.289 172.820 1.00 86.15 ? 231 ASP C CA 1 ATOM 1334 C C . ASP A 1 166 ? -161.971 -128.484 172.891 1.00 83.52 ? 231 ASP C C 1 ATOM 1335 O O . ASP A 1 166 ? -160.763 -128.343 172.709 1.00 83.44 ? 231 ASP C O 1 ATOM 1336 C CB . ASP A 1 166 ? -162.215 -126.034 172.285 1.00 85.06 ? 231 ASP C CB 1 ATOM 1337 C CG . ASP A 1 166 ? -161.647 -126.223 170.885 1.00 89.77 ? 231 ASP C CG 1 ATOM 1338 O OD1 . ASP A 1 166 ? -162.182 -127.081 170.138 1.00 90.58 ? 231 ASP C OD1 1 ATOM 1339 O OD2 . ASP A 1 166 ? -160.666 -125.508 170.540 1.00 87.25 ? 231 ASP C OD2 1 ATOM 1340 N N . LEU A 1 167 ? -162.511 -129.665 173.163 1.00 81.28 ? 232 LEU C N 1 ATOM 1341 C CA . LEU A 1 167 ? -161.670 -130.840 173.341 1.00 80.41 ? 232 LEU C CA 1 ATOM 1342 C C . LEU A 1 167 ? -160.963 -131.286 172.066 1.00 76.91 ? 232 LEU C C 1 ATOM 1343 O O . LEU A 1 167 ? -159.979 -132.015 172.137 1.00 80.86 ? 232 LEU C O 1 ATOM 1344 C CB . LEU A 1 167 ? -162.490 -131.996 173.915 1.00 86.29 ? 232 LEU C CB 1 ATOM 1345 C CG . LEU A 1 167 ? -162.966 -131.742 175.349 1.00 86.81 ? 232 LEU C CG 1 ATOM 1346 C CD1 . LEU A 1 167 ? -163.700 -132.962 175.907 1.00 83.38 ? 232 LEU C CD1 1 ATOM 1347 C CD2 . LEU A 1 167 ? -161.795 -131.344 176.245 1.00 79.40 ? 232 LEU C CD2 1 ATOM 1348 N N . GLY A 1 168 ? -161.461 -130.875 170.904 1.00 74.68 ? 233 GLY C N 1 ATOM 1349 C CA . GLY A 1 168 ? -160.762 -131.140 169.654 1.00 77.99 ? 233 GLY C CA 1 ATOM 1350 C C . GLY A 1 168 ? -160.777 -132.583 169.181 1.00 74.26 ? 233 GLY C C 1 ATOM 1351 O O . GLY A 1 168 ? -161.673 -133.341 169.520 1.00 78.43 ? 233 GLY C O 1 ATOM 1352 N N . ALA A 1 169 ? -159.803 -132.952 168.356 1.00 78.45 ? 234 ALA C N 1 ATOM 1353 C CA . ALA A 1 169 ? -159.744 -134.299 167.793 1.00 73.17 ? 234 ALA C CA 1 ATOM 1354 C C . ALA A 1 169 ? -159.278 -135.325 168.814 1.00 80.03 ? 234 ALA C C 1 ATOM 1355 O O . ALA A 1 169 ? -158.507 -135.018 169.719 1.00 83.28 ? 234 ALA C O 1 ATOM 1356 C CB . ALA A 1 169 ? -158.833 -134.323 166.590 1.00 69.87 ? 234 ALA C CB 1 ATOM 1357 N N . ILE A 1 170 ? -159.779 -136.546 168.693 1.00 89.69 ? 235 ILE C N 1 ATOM 1358 C CA . ILE A 1 170 ? -159.249 -137.652 169.480 1.00 84.46 ? 235 ILE C CA 1 ATOM 1359 C C . ILE A 1 170 ? -157.896 -138.019 168.924 1.00 83.57 ? 235 ILE C C 1 ATOM 1360 O O . ILE A 1 170 ? -157.708 -138.033 167.714 1.00 92.41 ? 235 ILE C O 1 ATOM 1361 C CB . ILE A 1 170 ? -160.166 -138.881 169.471 1.00 83.95 ? 235 ILE C CB 1 ATOM 1362 C CG1 . ILE A 1 170 ? -161.445 -138.591 170.261 1.00 77.73 ? 235 ILE C CG1 1 ATOM 1363 C CG2 . ILE A 1 170 ? -159.433 -140.089 170.034 1.00 82.04 ? 235 ILE C CG2 1 ATOM 1364 C CD1 . ILE A 1 170 ? -162.428 -139.728 170.283 1.00 81.36 ? 235 ILE C CD1 1 ATOM 1365 N N . LYS A 1 171 ? -156.967 -138.342 169.810 1.00 87.01 ? 236 LYS C N 1 ATOM 1366 C CA . LYS A 1 171 ? -155.595 -138.620 169.426 1.00 84.26 ? 236 LYS C CA 1 ATOM 1367 C C . LYS A 1 171 ? -155.327 -140.112 169.614 1.00 87.56 ? 236 LYS C C 1 ATOM 1368 O O . LYS A 1 171 ? -155.031 -140.563 170.722 1.00 86.47 ? 236 LYS C O 1 ATOM 1369 C CB . LYS A 1 171 ? -154.644 -137.761 170.258 1.00 82.64 ? 236 LYS C CB 1 ATOM 1370 C CG . LYS A 1 171 ? -153.426 -137.300 169.504 1.00 91.44 ? 236 LYS C CG 1 ATOM 1371 C CD . LYS A 1 171 ? -152.640 -136.247 170.276 1.00 85.90 ? 236 LYS C CD 1 ATOM 1372 C CE . LYS A 1 171 ? -151.167 -136.639 170.319 1.00 87.18 ? 236 LYS C CE 1 ATOM 1373 N NZ . LYS A 1 171 ? -150.673 -137.192 169.026 1.00 87.99 ? 236 LYS C NZ 1 ATOM 1374 N N . TRP A 1 172 ? -155.447 -140.871 168.526 1.00 90.38 ? 237 TRP C N 1 ATOM 1375 C CA . TRP A 1 172 ? -155.548 -142.329 168.616 1.00 89.40 ? 237 TRP C CA 1 ATOM 1376 C C . TRP A 1 172 ? -154.285 -142.992 169.142 1.00 87.38 ? 237 TRP C C 1 ATOM 1377 O O . TRP A 1 172 ? -154.361 -144.062 169.756 1.00 90.78 ? 237 TRP C O 1 ATOM 1378 C CB . TRP A 1 172 ? -155.962 -142.920 167.254 1.00 84.73 ? 237 TRP C CB 1 ATOM 1379 C CG . TRP A 1 172 ? -157.370 -142.518 166.954 1.00 90.42 ? 237 TRP C CG 1 ATOM 1380 C CD1 . TRP A 1 172 ? -157.791 -141.589 166.039 1.00 94.45 ? 237 TRP C CD1 1 ATOM 1381 C CD2 . TRP A 1 172 ? -158.546 -142.966 167.642 1.00 87.38 ? 237 TRP C CD2 1 ATOM 1382 N NE1 . TRP A 1 172 ? -159.164 -141.457 166.099 1.00 87.62 ? 237 TRP C NE1 1 ATOM 1383 C CE2 . TRP A 1 172 ? -159.647 -142.290 167.077 1.00 85.60 ? 237 TRP C CE2 1 ATOM 1384 C CE3 . TRP A 1 172 ? -158.775 -143.888 168.672 1.00 82.92 ? 237 TRP C CE3 1 ATOM 1385 C CZ2 . TRP A 1 172 ? -160.951 -142.503 167.511 1.00 79.09 ? 237 TRP C CZ2 1 ATOM 1386 C CZ3 . TRP A 1 172 ? -160.072 -144.102 169.098 1.00 78.53 ? 237 TRP C CZ3 1 ATOM 1387 C CH2 . TRP A 1 172 ? -161.143 -143.413 168.518 1.00 83.29 ? 237 TRP C CH2 1 ATOM 1388 N N . ASP A 1 173 ? -153.131 -142.367 168.946 1.00 82.13 ? 238 ASP C N 1 ATOM 1389 C CA . ASP A 1 173 ? -151.913 -142.937 169.517 1.00 86.72 ? 238 ASP C CA 1 ATOM 1390 C C . ASP A 1 173 ? -152.005 -142.914 171.054 1.00 85.36 ? 238 ASP C C 1 ATOM 1391 O O . ASP A 1 173 ? -151.523 -143.824 171.724 1.00 82.72 ? 238 ASP C O 1 ATOM 1392 C CB . ASP A 1 173 ? -150.664 -142.191 169.022 1.00 84.27 ? 238 ASP C CB 1 ATOM 1393 C CG . ASP A 1 173 ? -150.566 -140.771 169.572 1.00 91.78 ? 238 ASP C CG 1 ATOM 1394 O OD1 . ASP A 1 173 ? -151.615 -140.079 169.699 1.00 86.74 ? 238 ASP C OD1 1 ATOM 1395 O OD2 . ASP A 1 173 ? -149.426 -140.354 169.884 1.00 92.51 ? 238 ASP C OD2 1 ATOM 1396 N N . MET A 1 174 ? -152.659 -141.895 171.607 1.00 81.78 ? 239 MET C N 1 ATOM 1397 C CA . MET A 1 174 ? -152.882 -141.847 173.045 1.00 83.87 ? 239 MET C CA 1 ATOM 1398 C C . MET A 1 174 ? -153.929 -142.857 173.481 1.00 85.39 ? 239 MET C C 1 ATOM 1399 O O . MET A 1 174 ? -153.744 -143.549 174.481 1.00 85.07 ? 239 MET C O 1 ATOM 1400 C CB . MET A 1 174 ? -153.307 -140.449 173.491 1.00 85.61 ? 239 MET C CB 1 ATOM 1401 C CG . MET A 1 174 ? -152.152 -139.497 173.745 1.00 86.89 ? 239 MET C CG 1 ATOM 1402 S SD . MET A 1 174 ? -150.945 -140.152 174.915 1.00 89.69 ? 239 MET C SD 1 ATOM 1403 C CE . MET A 1 174 ? -151.953 -140.333 176.390 1.00 76.08 ? 239 MET C CE 1 ATOM 1404 N N . ALA A 1 175 ? -155.018 -142.952 172.720 1.00 86.86 ? 240 ALA C N 1 ATOM 1405 C CA . ALA A 1 175 ? -156.077 -143.904 173.029 1.00 85.40 ? 240 ALA C CA 1 ATOM 1406 C C . ALA A 1 175 ? -155.515 -145.318 173.011 1.00 86.90 ? 240 ALA C C 1 ATOM 1407 O O . ALA A 1 175 ? -155.946 -146.186 173.777 1.00 84.72 ? 240 ALA C O 1 ATOM 1408 C CB . ALA A 1 175 ? -157.220 -143.775 172.039 1.00 81.29 ? 240 ALA C CB 1 ATOM 1409 N N . LEU A 1 176 ? -154.525 -145.537 172.154 1.00 83.59 ? 241 LEU C N 1 ATOM 1410 C CA . LEU A 1 176 ? -153.870 -146.827 172.104 1.00 80.61 ? 241 LEU C CA 1 ATOM 1411 C C . LEU A 1 176 ? -153.150 -147.072 173.418 1.00 85.88 ? 241 LEU C C 1 ATOM 1412 O O . LEU A 1 176 ? -153.244 -148.162 173.992 1.00 93.77 ? 241 LEU C O 1 ATOM 1413 C CB . LEU A 1 176 ? -152.887 -146.902 170.943 1.00 80.13 ? 241 LEU C CB 1 ATOM 1414 C CG . LEU A 1 176 ? -152.251 -148.280 170.792 1.00 82.18 ? 241 LEU C CG 1 ATOM 1415 C CD1 . LEU A 1 176 ? -153.353 -149.326 170.729 1.00 83.42 ? 241 LEU C CD1 1 ATOM 1416 C CD2 . LEU A 1 176 ? -151.352 -148.339 169.558 1.00 71.29 ? 241 LEU C CD2 1 ATOM 1417 N N . CYS A 1 177 ? -152.432 -146.061 173.906 1.00 85.25 ? 242 CYS C N 1 ATOM 1418 C CA . CYS A 1 177 ? -151.735 -146.203 175.181 1.00 82.74 ? 242 CYS C CA 1 ATOM 1419 C C . CYS A 1 177 ? -152.729 -146.311 176.338 1.00 82.09 ? 242 CYS C C 1 ATOM 1420 O O . CYS A 1 177 ? -152.499 -147.046 177.299 1.00 84.97 ? 242 CYS C O 1 ATOM 1421 C CB . CYS A 1 177 ? -150.775 -145.038 175.401 1.00 77.56 ? 242 CYS C CB 1 ATOM 1422 S SG . CYS A 1 177 ? -149.433 -144.955 174.176 1.00 88.11 ? 242 CYS C SG 1 ATOM 1423 N N . LEU A 1 178 ? -153.843 -145.599 176.239 1.00 78.12 ? 243 LEU C N 1 ATOM 1424 C CA . LEU A 1 178 ? -154.841 -145.654 177.298 1.00 79.58 ? 243 LEU C CA 1 ATOM 1425 C C . LEU A 1 178 ? -155.466 -147.045 177.348 1.00 86.64 ? 243 LEU C C 1 ATOM 1426 O O . LEU A 1 178 ? -155.808 -147.546 178.421 1.00 81.78 ? 243 LEU C O 1 ATOM 1427 C CB . LEU A 1 178 ? -155.911 -144.587 177.095 1.00 78.63 ? 243 LEU C CB 1 ATOM 1428 C CG . LEU A 1 178 ? -156.968 -144.497 178.196 1.00 82.61 ? 243 LEU C CG 1 ATOM 1429 C CD1 . LEU A 1 178 ? -156.327 -144.376 179.572 1.00 74.57 ? 243 LEU C CD1 1 ATOM 1430 C CD2 . LEU A 1 178 ? -157.932 -143.341 177.929 1.00 83.18 ? 243 LEU C CD2 1 ATOM 1431 N N . LEU A 1 179 ? -155.574 -147.682 176.181 1.00 90.19 ? 244 LEU C N 1 ATOM 1432 C CA . LEU A 1 179 ? -156.177 -149.009 176.090 1.00 89.44 ? 244 LEU C CA 1 ATOM 1433 C C . LEU A 1 179 ? -155.231 -150.069 176.632 1.00 87.79 ? 244 LEU C C 1 ATOM 1434 O O . LEU A 1 179 ? -155.652 -150.968 177.364 1.00 86.62 ? 244 LEU C O 1 ATOM 1435 C CB . LEU A 1 179 ? -156.559 -149.343 174.646 1.00 93.49 ? 244 LEU C CB 1 ATOM 1436 C CG . LEU A 1 179 ? -157.179 -150.726 174.419 1.00 91.48 ? 244 LEU C CG 1 ATOM 1437 C CD1 . LEU A 1 179 ? -158.625 -150.783 174.924 1.00 89.36 ? 244 LEU C CD1 1 ATOM 1438 C CD2 . LEU A 1 179 ? -157.094 -151.108 172.955 1.00 86.83 ? 244 LEU C CD2 1 ATOM 1439 N N . ILE A 1 180 ? -153.952 -149.951 176.278 1.00 83.97 ? 245 ILE C N 1 ATOM 1440 C CA . ILE A 1 180 ? -152.947 -150.882 176.765 1.00 80.73 ? 245 ILE C CA 1 ATOM 1441 C C . ILE A 1 180 ? -152.901 -150.856 178.285 1.00 83.05 ? 245 ILE C C 1 ATOM 1442 O O . ILE A 1 180 ? -152.669 -151.883 178.923 1.00 83.03 ? 245 ILE C O 1 ATOM 1443 C CB . ILE A 1 180 ? -151.548 -150.541 176.232 1.00 81.07 ? 245 ILE C CB 1 ATOM 1444 C CG1 . ILE A 1 180 ? -151.465 -150.812 174.735 1.00 80.83 ? 245 ILE C CG1 1 ATOM 1445 C CG2 . ILE A 1 180 ? -150.469 -151.315 177.011 1.00 76.50 ? 245 ILE C CG2 1 ATOM 1446 C CD1 . ILE A 1 180 ? -150.130 -150.456 174.142 1.00 80.22 ? 245 ILE C CD1 1 ATOM 1447 N N . VAL A 1 181 ? -153.119 -149.677 178.862 1.00 81.46 ? 246 VAL C N 1 ATOM 1448 C CA . VAL A 1 181 ? -153.089 -149.550 180.302 1.00 81.04 ? 246 VAL C CA 1 ATOM 1449 C C . VAL A 1 181 ? -154.237 -150.371 180.855 1.00 82.11 ? 246 VAL C C 1 ATOM 1450 O O . VAL A 1 181 ? -154.039 -151.209 181.737 1.00 79.25 ? 246 VAL C O 1 ATOM 1451 C CB . VAL A 1 181 ? -153.190 -148.070 180.764 1.00 82.31 ? 246 VAL C CB 1 ATOM 1452 C CG1 . VAL A 1 181 ? -153.615 -147.971 182.231 1.00 75.67 ? 246 VAL C CG1 1 ATOM 1453 C CG2 . VAL A 1 181 ? -151.866 -147.367 180.554 1.00 80.93 ? 246 VAL C CG2 1 ATOM 1454 N N . TYR A 1 182 ? -155.424 -150.169 180.291 1.00 84.02 ? 247 TYR C N 1 ATOM 1455 C CA . TYR A 1 182 ? -156.619 -150.853 180.769 1.00 81.30 ? 247 TYR C CA 1 ATOM 1456 C C . TYR A 1 182 ? -156.567 -152.360 180.517 1.00 82.11 ? 247 TYR C C 1 ATOM 1457 O O . TYR A 1 182 ? -157.146 -153.140 181.277 1.00 86.03 ? 247 TYR C O 1 ATOM 1458 C CB . TYR A 1 182 ? -157.858 -150.249 180.118 1.00 81.20 ? 247 TYR C CB 1 ATOM 1459 C CG . TYR A 1 182 ? -158.234 -148.913 180.714 1.00 82.67 ? 247 TYR C CG 1 ATOM 1460 C CD1 . TYR A 1 182 ? -158.357 -148.758 182.087 1.00 88.04 ? 247 TYR C CD1 1 ATOM 1461 C CD2 . TYR A 1 182 ? -158.419 -147.797 179.911 1.00 83.08 ? 247 TYR C CD2 1 ATOM 1462 C CE1 . TYR A 1 182 ? -158.689 -147.533 182.643 1.00 91.02 ? 247 TYR C CE1 1 ATOM 1463 C CE2 . TYR A 1 182 ? -158.745 -146.569 180.455 1.00 82.83 ? 247 TYR C CE2 1 ATOM 1464 C CZ . TYR A 1 182 ? -158.879 -146.441 181.824 1.00 86.20 ? 247 TYR C CZ 1 ATOM 1465 O OH . TYR A 1 182 ? -159.204 -145.226 182.387 1.00 86.05 ? 247 TYR C OH 1 ATOM 1466 N N . LEU A 1 183 ? -155.874 -152.779 179.465 1.00 78.19 ? 248 LEU C N 1 ATOM 1467 C CA . LEU A 1 183 ? -155.705 -154.204 179.246 1.00 81.65 ? 248 LEU C CA 1 ATOM 1468 C C . LEU A 1 183 ? -154.830 -154.773 180.358 1.00 86.25 ? 248 LEU C C 1 ATOM 1469 O O . LEU A 1 183 ? -155.155 -155.793 180.959 1.00 89.08 ? 248 LEU C O 1 ATOM 1470 C CB . LEU A 1 183 ? -155.097 -154.494 177.867 1.00 84.74 ? 248 LEU C CB 1 ATOM 1471 C CG . LEU A 1 183 ? -156.038 -154.358 176.660 1.00 83.87 ? 248 LEU C CG 1 ATOM 1472 C CD1 . LEU A 1 183 ? -155.324 -154.695 175.361 1.00 80.02 ? 248 LEU C CD1 1 ATOM 1473 C CD2 . LEU A 1 183 ? -157.262 -155.223 176.837 1.00 73.30 ? 248 LEU C CD2 1 ATOM 1474 N N . ILE A 1 184 ? -153.746 -154.072 180.666 1.00 86.89 ? 249 ILE C N 1 ATOM 1475 C CA . ILE A 1 184 ? -152.841 -154.502 181.718 1.00 82.03 ? 249 ILE C CA 1 ATOM 1476 C C . ILE A 1 184 ? -153.577 -154.556 183.059 1.00 83.57 ? 249 ILE C C 1 ATOM 1477 O O . ILE A 1 184 ? -153.315 -155.417 183.903 1.00 86.80 ? 249 ILE C O 1 ATOM 1478 C CB . ILE A 1 184 ? -151.650 -153.538 181.838 1.00 75.81 ? 249 ILE C CB 1 ATOM 1479 C CG1 . ILE A 1 184 ? -150.821 -153.565 180.565 1.00 75.31 ? 249 ILE C CG1 1 ATOM 1480 C CG2 . ILE A 1 184 ? -150.799 -153.891 183.025 1.00 75.20 ? 249 ILE C CG2 1 ATOM 1481 C CD1 . ILE A 1 184 ? -149.640 -152.622 180.591 1.00 74.90 ? 249 ILE C CD1 1 ATOM 1482 N N . CYS A 1 185 ? -154.509 -153.638 183.250 1.00 76.28 ? 250 CYS C N 1 ATOM 1483 C CA . CYS A 1 185 ? -155.252 -153.597 184.495 1.00 82.47 ? 250 CYS C CA 1 ATOM 1484 C C . CYS A 1 185 ? -156.298 -154.694 184.532 1.00 89.22 ? 250 CYS C C 1 ATOM 1485 O O . CYS A 1 185 ? -156.605 -155.234 185.596 1.00 87.76 ? 250 CYS C O 1 ATOM 1486 C CB . CYS A 1 185 ? -155.913 -152.232 184.691 1.00 84.11 ? 250 CYS C CB 1 ATOM 1487 S SG . CYS A 1 185 ? -154.741 -150.880 184.946 1.00 95.18 ? 250 CYS C SG 1 ATOM 1488 N N . TYR A 1 186 ? -156.851 -155.018 183.368 1.00 90.63 ? 251 TYR C N 1 ATOM 1489 C CA . TYR A 1 186 ? -157.891 -156.029 183.304 1.00 87.67 ? 251 TYR C CA 1 ATOM 1490 C C . TYR A 1 186 ? -157.328 -157.399 183.626 1.00 90.86 ? 251 TYR C C 1 ATOM 1491 O O . TYR A 1 186 ? -157.876 -158.112 184.461 1.00 94.20 ? 251 TYR C O 1 ATOM 1492 C CB . TYR A 1 186 ? -158.545 -156.068 181.932 1.00 85.63 ? 251 TYR C CB 1 ATOM 1493 C CG . TYR A 1 186 ? -159.675 -157.068 181.885 1.00 93.54 ? 251 TYR C CG 1 ATOM 1494 C CD1 . TYR A 1 186 ? -160.983 -156.672 182.146 1.00 92.94 ? 251 TYR C CD1 1 ATOM 1495 C CD2 . TYR A 1 186 ? -159.437 -158.413 181.612 1.00 96.09 ? 251 TYR C CD2 1 ATOM 1496 C CE1 . TYR A 1 186 ? -162.020 -157.571 182.112 1.00 88.48 ? 251 TYR C CE1 1 ATOM 1497 C CE2 . TYR A 1 186 ? -160.474 -159.327 181.588 1.00 93.48 ? 251 TYR C CE2 1 ATOM 1498 C CZ . TYR A 1 186 ? -161.759 -158.891 181.840 1.00 89.61 ? 251 TYR C CZ 1 ATOM 1499 O OH . TYR A 1 186 ? -162.795 -159.777 181.817 1.00 91.35 ? 251 TYR C OH 1 ATOM 1500 N N . PHE A 1 187 ? -156.215 -157.744 182.984 1.00 84.55 ? 252 PHE C N 1 ATOM 1501 C CA . PHE A 1 187 ? -155.624 -159.068 183.123 1.00 86.12 ? 252 PHE C CA 1 ATOM 1502 C C . PHE A 1 187 ? -154.793 -159.133 184.385 1.00 93.15 ? 252 PHE C C 1 ATOM 1503 O O . PHE A 1 187 ? -154.112 -160.131 184.650 1.00 98.85 ? 252 PHE C O 1 ATOM 1504 C CB . PHE A 1 187 ? -154.784 -159.442 181.895 1.00 88.56 ? 252 PHE C CB 1 ATOM 1505 C CG . PHE A 1 187 ? -155.596 -159.582 180.631 1.00 97.39 ? 252 PHE C CG 1 ATOM 1506 C CD1 . PHE A 1 187 ? -156.474 -160.647 180.464 1.00 93.73 ? 252 PHE C CD1 1 ATOM 1507 C CD2 . PHE A 1 187 ? -155.492 -158.641 179.617 1.00 93.49 ? 252 PHE C CD2 1 ATOM 1508 C CE1 . PHE A 1 187 ? -157.224 -160.767 179.313 1.00 94.93 ? 252 PHE C CE1 1 ATOM 1509 C CE2 . PHE A 1 187 ? -156.234 -158.760 178.465 1.00 87.00 ? 252 PHE C CE2 1 ATOM 1510 C CZ . PHE A 1 187 ? -157.101 -159.826 178.311 1.00 93.45 ? 252 PHE C CZ 1 ATOM 1511 N N . SER A 1 188 ? -154.821 -158.036 185.136 1.00 90.97 ? 253 SER C N 1 ATOM 1512 C CA . SER A 1 188 ? -154.253 -158.006 186.472 1.00 88.10 ? 253 SER C CA 1 ATOM 1513 C C . SER A 1 188 ? -155.333 -158.227 187.537 1.00 87.40 ? 253 SER C C 1 ATOM 1514 O O . SER A 1 188 ? -155.054 -158.717 188.633 1.00 91.63 ? 253 SER C O 1 ATOM 1515 C CB . SER A 1 188 ? -153.532 -156.679 186.704 1.00 83.66 ? 253 SER C CB 1 ATOM 1516 O OG . SER A 1 188 ? -152.239 -156.683 186.121 1.00 75.59 ? 253 SER C OG 1 ATOM 1517 N N . LEU A 1 189 ? -156.573 -157.888 187.202 1.00 87.22 ? 254 LEU C N 1 ATOM 1518 C CA . LEU A 1 189 ? -157.622 -157.838 188.211 1.00 89.77 ? 254 LEU C CA 1 ATOM 1519 C C . LEU A 1 189 ? -158.813 -158.769 187.980 1.00 96.45 ? 254 LEU C C 1 ATOM 1520 O O . LEU A 1 189 ? -159.662 -158.884 188.866 1.00 100.18 ? 254 LEU C O 1 ATOM 1521 C CB . LEU A 1 189 ? -158.145 -156.402 188.342 1.00 85.75 ? 254 LEU C CB 1 ATOM 1522 C CG . LEU A 1 189 ? -157.182 -155.329 188.843 1.00 79.95 ? 254 LEU C CG 1 ATOM 1523 C CD1 . LEU A 1 189 ? -157.879 -153.993 188.892 1.00 84.17 ? 254 LEU C CD1 1 ATOM 1524 C CD2 . LEU A 1 189 ? -156.663 -155.694 190.202 1.00 78.41 ? 254 LEU C CD2 1 ATOM 1525 N N . TRP A 1 190 ? -158.920 -159.404 186.810 1.00 99.90 ? 255 TRP C N 1 ATOM 1526 C CA . TRP A 1 190 ? -160.121 -160.208 186.538 1.00 102.01 ? 255 TRP C CA 1 ATOM 1527 C C . TRP A 1 190 ? -160.193 -161.459 187.412 1.00 99.68 ? 255 TRP C C 1 ATOM 1528 O O . TRP A 1 190 ? -161.267 -161.828 187.886 1.00 97.54 ? 255 TRP C O 1 ATOM 1529 C CB . TRP A 1 190 ? -160.221 -160.598 185.050 1.00 102.11 ? 255 TRP C CB 1 ATOM 1530 C CG . TRP A 1 190 ? -159.074 -161.381 184.507 1.00 100.52 ? 255 TRP C CG 1 ATOM 1531 C CD1 . TRP A 1 190 ? -157.960 -160.880 183.938 1.00 105.56 ? 255 TRP C CD1 1 ATOM 1532 C CD2 . TRP A 1 190 ? -158.942 -162.804 184.454 1.00 112.36 ? 255 TRP C CD2 1 ATOM 1533 N NE1 . TRP A 1 190 ? -157.117 -161.889 183.544 1.00 106.31 ? 255 TRP C NE1 1 ATOM 1534 C CE2 . TRP A 1 190 ? -157.698 -163.086 183.848 1.00 111.93 ? 255 TRP C CE2 1 ATOM 1535 C CE3 . TRP A 1 190 ? -159.741 -163.871 184.881 1.00 123.35 ? 255 TRP C CE3 1 ATOM 1536 C CZ2 . TRP A 1 190 ? -157.234 -164.385 183.649 1.00 127.00 ? 255 TRP C CZ2 1 ATOM 1537 C CZ3 . TRP A 1 190 ? -159.279 -165.169 184.687 1.00 126.27 ? 255 TRP C CZ3 1 ATOM 1538 C CH2 . TRP A 1 190 ? -158.036 -165.412 184.073 1.00 134.20 ? 255 TRP C CH2 1 ATOM 1539 N N . LYS A 1 191 ? -159.044 -162.075 187.661 1.00 100.15 ? 256 LYS C N 1 ATOM 1540 C CA . LYS A 1 191 ? -159.001 -163.325 188.414 1.00 102.63 ? 256 LYS C CA 1 ATOM 1541 C C . LYS A 1 191 ? -158.971 -163.100 189.931 1.00 98.33 ? 256 LYS C C 1 ATOM 1542 O O . LYS A 1 191 ? -158.952 -164.059 190.704 1.00 100.68 ? 256 LYS C O 1 ATOM 1543 C CB . LYS A 1 191 ? -157.790 -164.160 187.975 1.00 100.20 ? 256 LYS C CB 1 ATOM 1544 N N . GLY A 1 192 ? -158.964 -161.839 190.356 1.00 99.22 ? 257 GLY C N 1 ATOM 1545 C CA . GLY A 1 192 ? -158.860 -161.523 191.770 1.00 93.74 ? 257 GLY C CA 1 ATOM 1546 C C . GLY A 1 192 ? -157.434 -161.479 192.304 1.00 92.13 ? 257 GLY C C 1 ATOM 1547 O O . GLY A 1 192 ? -156.461 -161.477 191.535 1.00 91.32 ? 257 GLY C O 1 ATOM 1548 N N . ILE A 1 193 ? -157.305 -161.447 193.629 1.00 88.73 ? 258 ILE C N 1 ATOM 1549 C CA . ILE A 1 193 ? -156.015 -161.186 194.267 1.00 86.25 ? 258 ILE C CA 1 ATOM 1550 C C . ILE A 1 193 ? -154.990 -162.299 194.035 1.00 84.95 ? 258 ILE C C 1 ATOM 1551 O O . ILE A 1 193 ? -153.799 -162.108 194.270 1.00 87.50 ? 258 ILE C O 1 ATOM 1552 C CB . ILE A 1 193 ? -156.181 -160.958 195.781 1.00 82.38 ? 258 ILE C CB 1 ATOM 1553 C CG1 . ILE A 1 193 ? -156.893 -162.140 196.428 1.00 87.00 ? 258 ILE C CG1 1 ATOM 1554 C CG2 . ILE A 1 193 ? -156.937 -159.663 196.053 1.00 79.63 ? 258 ILE C CG2 1 ATOM 1555 C CD1 . ILE A 1 193 ? -157.160 -161.950 197.922 1.00 87.74 ? 258 ILE C CD1 1 ATOM 1556 N N . SER A 1 194 ? -155.460 -163.457 193.587 1.00 88.45 ? 259 SER C N 1 ATOM 1557 C CA . SER A 1 194 ? -154.593 -164.603 193.316 1.00 89.88 ? 259 SER C CA 1 ATOM 1558 C C . SER A 1 194 ? -153.566 -164.268 192.231 1.00 94.16 ? 259 SER C C 1 ATOM 1559 O O . SER A 1 194 ? -152.443 -164.792 192.227 1.00 92.44 ? 259 SER C O 1 ATOM 1560 C CB . SER A 1 194 ? -155.427 -165.819 192.897 1.00 85.03 ? 259 SER C CB 1 ATOM 1561 O OG . SER A 1 194 ? -156.816 -165.516 192.956 1.00 87.39 ? 259 SER C OG 1 ATOM 1562 N N . THR A 1 195 ? -153.948 -163.389 191.309 1.00 92.35 ? 260 THR C N 1 ATOM 1563 C CA . THR A 1 195 ? -153.006 -162.918 190.299 1.00 93.98 ? 260 THR C CA 1 ATOM 1564 C C . THR A 1 195 ? -152.620 -161.460 190.530 1.00 90.13 ? 260 THR C C 1 ATOM 1565 O O . THR A 1 195 ? -151.495 -161.050 190.221 1.00 87.77 ? 260 THR C O 1 ATOM 1566 C CB . THR A 1 195 ? -153.584 -163.051 188.888 1.00 92.27 ? 260 THR C CB 1 ATOM 1567 O OG1 . THR A 1 195 ? -154.777 -162.265 188.803 1.00 98.40 ? 260 THR C OG1 1 ATOM 1568 C CG2 . THR A 1 195 ? -153.913 -164.507 188.582 1.00 97.62 ? 260 THR C CG2 1 ATOM 1569 N N . SER A 1 196 ? -153.558 -160.676 191.062 1.00 86.49 ? 261 SER C N 1 ATOM 1570 C CA . SER A 1 196 ? -153.295 -159.261 191.290 1.00 81.58 ? 261 SER C CA 1 ATOM 1571 C C . SER A 1 196 ? -152.173 -159.118 192.302 1.00 84.76 ? 261 SER C C 1 ATOM 1572 O O . SER A 1 196 ? -151.307 -158.253 192.170 1.00 83.21 ? 261 SER C O 1 ATOM 1573 C CB . SER A 1 196 ? -154.546 -158.541 191.782 1.00 79.13 ? 261 SER C CB 1 ATOM 1574 O OG . SER A 1 196 ? -154.495 -158.310 193.181 1.00 77.64 ? 261 SER C OG 1 ATOM 1575 N N . GLY A 1 197 ? -152.143 -160.027 193.270 1.00 83.99 ? 262 GLY C N 1 ATOM 1576 C CA . GLY A 1 197 ? -151.137 -159.982 194.310 1.00 78.47 ? 262 GLY C CA 1 ATOM 1577 C C . GLY A 1 197 ? -149.831 -160.592 193.852 1.00 82.17 ? 262 GLY C C 1 ATOM 1578 O O . GLY A 1 197 ? -148.856 -160.629 194.599 1.00 81.52 ? 262 GLY C O 1 ATOM 1579 N N . LYS A 1 198 ? -149.819 -161.118 192.634 1.00 84.91 ? 263 LYS C N 1 ATOM 1580 C CA . LYS A 1 198 ? -148.588 -161.667 192.079 1.00 86.31 ? 263 LYS C CA 1 ATOM 1581 C C . LYS A 1 198 ? -148.007 -160.663 191.099 1.00 81.78 ? 263 LYS C C 1 ATOM 1582 O O . LYS A 1 198 ? -146.791 -160.519 190.972 1.00 76.32 ? 263 LYS C O 1 ATOM 1583 C CB . LYS A 1 198 ? -148.852 -163.020 191.403 1.00 85.31 ? 263 LYS C CB 1 ATOM 1584 N N . VAL A 1 199 ? -148.896 -159.950 190.419 1.00 84.01 ? 264 VAL C N 1 ATOM 1585 C CA . VAL A 1 199 ? -148.482 -158.933 189.458 1.00 80.96 ? 264 VAL C CA 1 ATOM 1586 C C . VAL A 1 199 ? -147.715 -157.807 190.142 1.00 81.46 ? 264 VAL C C 1 ATOM 1587 O O . VAL A 1 199 ? -146.797 -157.206 189.563 1.00 78.85 ? 264 VAL C O 1 ATOM 1588 C CB . VAL A 1 199 ? -149.680 -158.327 188.731 1.00 78.98 ? 264 VAL C CB 1 ATOM 1589 C CG1 . VAL A 1 199 ? -149.233 -157.194 187.847 1.00 83.78 ? 264 VAL C CG1 1 ATOM 1590 C CG2 . VAL A 1 199 ? -150.379 -159.386 187.912 1.00 81.47 ? 264 VAL C CG2 1 ATOM 1591 N N . VAL A 1 200 ? -148.076 -157.534 191.390 1.00 81.17 ? 265 VAL C N 1 ATOM 1592 C CA . VAL A 1 200 ? -147.527 -156.383 192.077 1.00 79.27 ? 265 VAL C CA 1 ATOM 1593 C C . VAL A 1 200 ? -146.067 -156.624 192.418 1.00 78.64 ? 265 VAL C C 1 ATOM 1594 O O . VAL A 1 200 ? -145.338 -155.691 192.737 1.00 81.53 ? 265 VAL C O 1 ATOM 1595 C CB . VAL A 1 200 ? -148.314 -156.054 193.345 1.00 78.62 ? 265 VAL C CB 1 ATOM 1596 C CG1 . VAL A 1 200 ? -149.721 -155.621 192.983 1.00 70.91 ? 265 VAL C CG1 1 ATOM 1597 C CG2 . VAL A 1 200 ? -148.321 -157.252 194.276 1.00 81.59 ? 265 VAL C CG2 1 ATOM 1598 N N . TRP A 1 201 ? -145.636 -157.876 192.335 1.00 81.41 ? 266 TRP C N 1 ATOM 1599 C CA . TRP A 1 201 ? -144.235 -158.184 192.588 1.00 83.47 ? 266 TRP C CA 1 ATOM 1600 C C . TRP A 1 201 ? -143.373 -157.427 191.604 1.00 84.83 ? 266 TRP C C 1 ATOM 1601 O O . TRP A 1 201 ? -142.274 -156.976 191.949 1.00 81.45 ? 266 TRP C O 1 ATOM 1602 C CB . TRP A 1 201 ? -143.969 -159.676 192.465 1.00 80.06 ? 266 TRP C CB 1 ATOM 1603 C CG . TRP A 1 201 ? -144.460 -160.432 193.638 1.00 82.54 ? 266 TRP C CG 1 ATOM 1604 C CD1 . TRP A 1 201 ? -145.758 -160.596 194.024 1.00 82.19 ? 266 TRP C CD1 1 ATOM 1605 C CD2 . TRP A 1 201 ? -143.661 -161.137 194.590 1.00 85.86 ? 266 TRP C CD2 1 ATOM 1606 N NE1 . TRP A 1 201 ? -145.812 -161.357 195.163 1.00 83.86 ? 266 TRP C NE1 1 ATOM 1607 C CE2 . TRP A 1 201 ? -144.539 -161.706 195.528 1.00 83.18 ? 266 TRP C CE2 1 ATOM 1608 C CE3 . TRP A 1 201 ? -142.282 -161.338 194.741 1.00 86.31 ? 266 TRP C CE3 1 ATOM 1609 C CZ2 . TRP A 1 201 ? -144.091 -162.469 196.599 1.00 88.06 ? 266 TRP C CZ2 1 ATOM 1610 C CZ3 . TRP A 1 201 ? -141.834 -162.089 195.811 1.00 85.95 ? 266 TRP C CZ3 1 ATOM 1611 C CH2 . TRP A 1 201 ? -142.737 -162.643 196.730 1.00 89.48 ? 266 TRP C CH2 1 ATOM 1612 N N . PHE A 1 202 ? -143.895 -157.256 190.386 1.00 83.16 ? 267 PHE C N 1 ATOM 1613 C CA . PHE A 1 202 ? -143.188 -156.493 189.373 1.00 76.20 ? 267 PHE C CA 1 ATOM 1614 C C . PHE A 1 202 ? -143.434 -155.014 189.587 1.00 78.59 ? 267 PHE C C 1 ATOM 1615 O O . PHE A 1 202 ? -142.493 -154.244 189.800 1.00 77.06 ? 267 PHE C O 1 ATOM 1616 C CB . PHE A 1 202 ? -143.622 -156.888 187.964 1.00 75.51 ? 267 PHE C CB 1 ATOM 1617 C CG . PHE A 1 202 ? -142.932 -156.091 186.883 1.00 78.99 ? 267 PHE C CG 1 ATOM 1618 C CD1 . PHE A 1 202 ? -141.568 -156.225 186.674 1.00 76.89 ? 267 PHE C CD1 1 ATOM 1619 C CD2 . PHE A 1 202 ? -143.639 -155.191 186.092 1.00 78.04 ? 267 PHE C CD2 1 ATOM 1620 C CE1 . PHE A 1 202 ? -140.924 -155.490 185.699 1.00 75.96 ? 267 PHE C CE1 1 ATOM 1621 C CE2 . PHE A 1 202 ? -142.995 -154.445 185.107 1.00 78.69 ? 267 PHE C CE2 1 ATOM 1622 C CZ . PHE A 1 202 ? -141.634 -154.597 184.913 1.00 77.73 ? 267 PHE C CZ 1 ATOM 1623 N N . THR A 1 203 ? -144.709 -154.630 189.554 1.00 75.37 ? 268 THR C N 1 ATOM 1624 C CA . THR A 1 203 ? -145.076 -153.219 189.548 1.00 76.08 ? 268 THR C CA 1 ATOM 1625 C C . THR A 1 203 ? -144.674 -152.490 190.841 1.00 78.31 ? 268 THR C C 1 ATOM 1626 O O . THR A 1 203 ? -144.496 -151.258 190.844 1.00 75.39 ? 268 THR C O 1 ATOM 1627 C CB . THR A 1 203 ? -146.568 -153.054 189.313 1.00 67.86 ? 268 THR C CB 1 ATOM 1628 O OG1 . THR A 1 203 ? -147.294 -153.584 190.427 1.00 72.07 ? 268 THR C OG1 1 ATOM 1629 C CG2 . THR A 1 203 ? -146.968 -153.797 188.068 1.00 71.73 ? 268 THR C CG2 1 ATOM 1630 N N . ALA A 1 204 ? -144.553 -153.238 191.936 1.00 73.66 ? 269 ALA C N 1 ATOM 1631 C CA . ALA A 1 204 ? -144.176 -152.639 193.212 1.00 76.77 ? 269 ALA C CA 1 ATOM 1632 C C . ALA A 1 204 ? -142.664 -152.653 193.419 1.00 79.38 ? 269 ALA C C 1 ATOM 1633 O O . ALA A 1 204 ? -142.120 -151.807 194.144 1.00 75.54 ? 269 ALA C O 1 ATOM 1634 C CB . ALA A 1 204 ? -144.877 -153.345 194.373 1.00 74.29 ? 269 ALA C CB 1 ATOM 1635 N N . LEU A 1 205 ? -141.989 -153.609 192.779 1.00 77.18 ? 270 LEU C N 1 ATOM 1636 C CA . LEU A 1 205 ? -140.552 -153.797 192.987 1.00 76.75 ? 270 LEU C CA 1 ATOM 1637 C C . LEU A 1 205 ? -139.699 -153.133 191.915 1.00 74.29 ? 270 LEU C C 1 ATOM 1638 O O . LEU A 1 205 ? -138.596 -152.655 192.190 1.00 77.65 ? 270 LEU C O 1 ATOM 1639 C CB . LEU A 1 205 ? -140.212 -155.294 193.055 1.00 77.99 ? 270 LEU C CB 1 ATOM 1640 C CG . LEU A 1 205 ? -140.666 -156.082 194.291 1.00 78.61 ? 270 LEU C CG 1 ATOM 1641 C CD1 . LEU A 1 205 ? -140.107 -157.493 194.234 1.00 77.39 ? 270 LEU C CD1 1 ATOM 1642 C CD2 . LEU A 1 205 ? -140.249 -155.376 195.572 1.00 69.41 ? 270 LEU C CD2 1 ATOM 1643 N N . PHE A 1 206 ? -140.215 -153.097 190.699 1.00 74.57 ? 271 PHE C N 1 ATOM 1644 C CA . PHE A 1 206 ? -139.474 -152.559 189.569 1.00 72.43 ? 271 PHE C CA 1 ATOM 1645 C C . PHE A 1 206 ? -138.982 -151.134 189.813 1.00 76.00 ? 271 PHE C C 1 ATOM 1646 O O . PHE A 1 206 ? -137.833 -150.808 189.526 1.00 79.62 ? 271 PHE C O 1 ATOM 1647 C CB . PHE A 1 206 ? -140.337 -152.608 188.303 1.00 75.03 ? 271 PHE C CB 1 ATOM 1648 C CG . PHE A 1 206 ? -139.634 -152.135 187.069 1.00 80.69 ? 271 PHE C CG 1 ATOM 1649 C CD1 . PHE A 1 206 ? -138.972 -153.030 186.252 1.00 82.76 ? 271 PHE C CD1 1 ATOM 1650 C CD2 . PHE A 1 206 ? -139.633 -150.793 186.730 1.00 82.09 ? 271 PHE C CD2 1 ATOM 1651 C CE1 . PHE A 1 206 ? -138.328 -152.593 185.120 1.00 82.55 ? 271 PHE C CE1 1 ATOM 1652 C CE2 . PHE A 1 206 ? -138.989 -150.352 185.594 1.00 81.91 ? 271 PHE C CE2 1 ATOM 1653 C CZ . PHE A 1 206 ? -138.337 -151.253 184.789 1.00 84.92 ? 271 PHE C CZ 1 ATOM 1654 N N . PRO A 1 207 ? -139.849 -150.273 190.373 1.00 77.14 ? 272 PRO C N 1 ATOM 1655 C CA . PRO A 1 207 ? -139.442 -148.883 190.588 1.00 73.22 ? 272 PRO C CA 1 ATOM 1656 C C . PRO A 1 207 ? -138.201 -148.766 191.461 1.00 75.26 ? 272 PRO C C 1 ATOM 1657 O O . PRO A 1 207 ? -137.415 -147.838 191.266 1.00 78.58 ? 272 PRO C O 1 ATOM 1658 C CB . PRO A 1 207 ? -140.649 -148.284 191.307 1.00 71.05 ? 272 PRO C CB 1 ATOM 1659 C CG . PRO A 1 207 ? -141.800 -149.136 190.891 1.00 75.22 ? 272 PRO C CG 1 ATOM 1660 C CD . PRO A 1 207 ? -141.234 -150.515 190.807 1.00 75.98 ? 272 PRO C CD 1 ATOM 1661 N N . TYR A 1 208 ? -138.037 -149.664 192.423 1.00 73.61 ? 273 TYR C N 1 ATOM 1662 C CA . TYR A 1 208 ? -136.862 -149.610 193.276 1.00 72.36 ? 273 TYR C CA 1 ATOM 1663 C C . TYR A 1 208 ? -135.603 -150.002 192.508 1.00 77.05 ? 273 TYR C C 1 ATOM 1664 O O . TYR A 1 208 ? -134.514 -149.478 192.769 1.00 75.57 ? 273 TYR C O 1 ATOM 1665 C CB . TYR A 1 208 ? -137.053 -150.491 194.499 1.00 73.72 ? 273 TYR C CB 1 ATOM 1666 C CG . TYR A 1 208 ? -138.144 -149.961 195.405 1.00 78.48 ? 273 TYR C CG 1 ATOM 1667 C CD1 . TYR A 1 208 ? -137.944 -148.795 196.153 1.00 71.05 ? 273 TYR C CD1 1 ATOM 1668 C CD2 . TYR A 1 208 ? -139.379 -150.611 195.509 1.00 74.24 ? 273 TYR C CD2 1 ATOM 1669 C CE1 . TYR A 1 208 ? -138.936 -148.291 196.971 1.00 69.25 ? 273 TYR C CE1 1 ATOM 1670 C CE2 . TYR A 1 208 ? -140.380 -150.112 196.334 1.00 74.55 ? 273 TYR C CE2 1 ATOM 1671 C CZ . TYR A 1 208 ? -140.150 -148.953 197.059 1.00 75.30 ? 273 TYR C CZ 1 ATOM 1672 O OH . TYR A 1 208 ? -141.142 -148.456 197.878 1.00 76.96 ? 273 TYR C OH 1 ATOM 1673 N N . ALA A 1 209 ? -135.743 -150.893 191.533 1.00 73.44 ? 274 ALA C N 1 ATOM 1674 C CA . ALA A 1 209 ? -134.587 -151.236 190.730 1.00 69.21 ? 274 ALA C CA 1 ATOM 1675 C C . ALA A 1 209 ? -134.138 -149.995 189.978 1.00 75.93 ? 274 ALA C C 1 ATOM 1676 O O . ALA A 1 209 ? -132.964 -149.624 190.031 1.00 78.33 ? 274 ALA C O 1 ATOM 1677 C CB . ALA A 1 209 ? -134.905 -152.356 189.774 1.00 68.85 ? 274 ALA C CB 1 ATOM 1678 N N . VAL A 1 210 ? -135.087 -149.347 189.299 1.00 74.63 ? 275 VAL C N 1 ATOM 1679 C CA . VAL A 1 210 ? -134.820 -148.118 188.553 1.00 72.26 ? 275 VAL C CA 1 ATOM 1680 C C . VAL A 1 210 ? -134.416 -146.952 189.459 1.00 73.49 ? 275 VAL C C 1 ATOM 1681 O O . VAL A 1 210 ? -133.557 -146.143 189.103 1.00 69.99 ? 275 VAL C O 1 ATOM 1682 C CB . VAL A 1 210 ? -136.050 -147.709 187.726 1.00 72.30 ? 275 VAL C CB 1 ATOM 1683 C CG1 . VAL A 1 210 ? -135.745 -146.513 186.853 1.00 71.61 ? 275 VAL C CG1 1 ATOM 1684 C CG2 . VAL A 1 210 ? -136.505 -148.869 186.877 1.00 76.95 ? 275 VAL C CG2 1 ATOM 1685 N N . LEU A 1 211 ? -135.004 -146.877 190.647 1.00 75.31 ? 276 LEU C N 1 ATOM 1686 C CA . LEU A 1 211 ? -134.648 -145.800 191.559 1.00 77.85 ? 276 LEU C CA 1 ATOM 1687 C C . LEU A 1 211 ? -133.167 -145.893 191.936 1.00 79.18 ? 276 LEU C C 1 ATOM 1688 O O . LEU A 1 211 ? -132.483 -144.878 192.063 1.00 79.25 ? 276 LEU C O 1 ATOM 1689 C CB . LEU A 1 211 ? -135.513 -145.844 192.820 1.00 77.74 ? 276 LEU C CB 1 ATOM 1690 C CG . LEU A 1 211 ? -136.853 -145.112 192.847 1.00 77.16 ? 276 LEU C CG 1 ATOM 1691 C CD1 . LEU A 1 211 ? -137.293 -144.984 194.280 1.00 71.45 ? 276 LEU C CD1 1 ATOM 1692 C CD2 . LEU A 1 211 ? -136.744 -143.740 192.215 1.00 75.37 ? 276 LEU C CD2 1 ATOM 1693 N N . LEU A 1 212 ? -132.675 -147.121 192.070 1.00 81.71 ? 277 LEU C N 1 ATOM 1694 C CA . LEU A 1 212 ? -131.279 -147.371 192.420 1.00 80.37 ? 277 LEU C CA 1 ATOM 1695 C C . LEU A 1 212 ? -130.348 -146.994 191.262 1.00 83.01 ? 277 LEU C C 1 ATOM 1696 O O . LEU A 1 212 ? -129.332 -146.314 191.452 1.00 83.08 ? 277 LEU C O 1 ATOM 1697 C CB . LEU A 1 212 ? -131.095 -148.842 192.793 1.00 78.91 ? 277 LEU C CB 1 ATOM 1698 C CG . LEU A 1 212 ? -129.705 -149.392 193.101 1.00 77.70 ? 277 LEU C CG 1 ATOM 1699 C CD1 . LEU A 1 212 ? -129.187 -148.857 194.432 1.00 78.19 ? 277 LEU C CD1 1 ATOM 1700 C CD2 . LEU A 1 212 ? -129.750 -150.920 193.093 1.00 69.60 ? 277 LEU C CD2 1 ATOM 1701 N N . ILE A 1 213 ? -130.714 -147.421 190.057 1.00 79.49 ? 278 ILE C N 1 ATOM 1702 C CA . ILE A 1 213 ? -129.901 -147.151 188.885 1.00 76.38 ? 278 ILE C CA 1 ATOM 1703 C C . ILE A 1 213 ? -129.821 -145.648 188.627 1.00 79.36 ? 278 ILE C C 1 ATOM 1704 O O . ILE A 1 213 ? -128.747 -145.105 188.380 1.00 82.55 ? 278 ILE C O 1 ATOM 1705 C CB . ILE A 1 213 ? -130.470 -147.872 187.658 1.00 73.59 ? 278 ILE C CB 1 ATOM 1706 C CG1 . ILE A 1 213 ? -130.403 -149.390 187.851 1.00 75.60 ? 278 ILE C CG1 1 ATOM 1707 C CG2 . ILE A 1 213 ? -129.721 -147.487 186.430 1.00 74.32 ? 278 ILE C CG2 1 ATOM 1708 C CD1 . ILE A 1 213 ? -130.976 -150.177 186.687 1.00 69.93 ? 278 ILE C CD1 1 ATOM 1709 N N . LEU A 1 214 ? -130.961 -144.974 188.698 1.00 80.71 ? 279 LEU C N 1 ATOM 1710 C CA . LEU A 1 214 ? -131.007 -143.529 188.525 1.00 76.10 ? 279 LEU C CA 1 ATOM 1711 C C . LEU A 1 214 ? -130.354 -142.810 189.683 1.00 73.91 ? 279 LEU C C 1 ATOM 1712 O O . LEU A 1 214 ? -129.829 -141.717 189.529 1.00 75.76 ? 279 LEU C O 1 ATOM 1713 C CB . LEU A 1 214 ? -132.456 -143.059 188.372 1.00 75.94 ? 279 LEU C CB 1 ATOM 1714 C CG . LEU A 1 214 ? -133.066 -143.483 187.038 1.00 71.11 ? 279 LEU C CG 1 ATOM 1715 C CD1 . LEU A 1 214 ? -134.506 -143.010 186.891 1.00 71.19 ? 279 LEU C CD1 1 ATOM 1716 C CD2 . LEU A 1 214 ? -132.190 -142.952 185.927 1.00 72.29 ? 279 LEU C CD2 1 ATOM 1717 N N . LEU A 1 215 ? -130.398 -143.411 190.858 1.00 77.16 ? 280 LEU C N 1 ATOM 1718 C CA . LEU A 1 215 ? -129.790 -142.782 192.019 1.00 79.02 ? 280 LEU C CA 1 ATOM 1719 C C . LEU A 1 215 ? -128.271 -142.738 191.842 1.00 81.04 ? 280 LEU C C 1 ATOM 1720 O O . LEU A 1 215 ? -127.606 -141.824 192.330 1.00 80.25 ? 280 LEU C O 1 ATOM 1721 C CB . LEU A 1 215 ? -130.174 -143.523 193.306 1.00 76.34 ? 280 LEU C CB 1 ATOM 1722 C CG . LEU A 1 215 ? -129.484 -143.109 194.604 1.00 75.89 ? 280 LEU C CG 1 ATOM 1723 C CD1 . LEU A 1 215 ? -129.618 -141.601 194.855 1.00 72.52 ? 280 LEU C CD1 1 ATOM 1724 C CD2 . LEU A 1 215 ? -130.005 -143.937 195.789 1.00 69.42 ? 280 LEU C CD2 1 ATOM 1725 N N . ILE A 1 216 ? -127.724 -143.721 191.125 1.00 82.39 ? 281 ILE C N 1 ATOM 1726 C CA . ILE A 1 216 ? -126.274 -143.804 190.939 1.00 83.16 ? 281 ILE C CA 1 ATOM 1727 C C . ILE A 1 216 ? -125.815 -142.910 189.801 1.00 82.46 ? 281 ILE C C 1 ATOM 1728 O O . ILE A 1 216 ? -124.838 -142.173 189.931 1.00 85.25 ? 281 ILE C O 1 ATOM 1729 C CB . ILE A 1 216 ? -125.817 -145.251 190.670 1.00 86.59 ? 281 ILE C CB 1 ATOM 1730 C CG1 . ILE A 1 216 ? -125.980 -146.109 191.931 1.00 85.74 ? 281 ILE C CG1 1 ATOM 1731 C CG2 . ILE A 1 216 ? -124.372 -145.275 190.232 1.00 85.08 ? 281 ILE C CG2 1 ATOM 1732 C CD1 . ILE A 1 216 ? -126.242 -147.575 191.625 1.00 86.25 ? 281 ILE C CD1 1 ATOM 1733 N N . ARG A 1 217 ? -126.543 -142.963 188.692 1.00 81.12 ? 282 ARG C N 1 ATOM 1734 C CA . ARG A 1 217 ? -126.255 -142.090 187.569 1.00 81.87 ? 282 ARG C CA 1 ATOM 1735 C C . ARG A 1 217 ? -126.461 -140.655 188.021 1.00 85.48 ? 282 ARG C C 1 ATOM 1736 O O . ARG A 1 217 ? -125.776 -139.741 187.567 1.00 90.11 ? 282 ARG C O 1 ATOM 1737 C CB . ARG A 1 217 ? -127.152 -142.408 186.366 1.00 82.78 ? 282 ARG C CB 1 ATOM 1738 C CG . ARG A 1 217 ? -126.721 -141.688 185.106 1.00 83.64 ? 282 ARG C CG 1 ATOM 1739 C CD . ARG A 1 217 ? -125.226 -141.454 185.222 1.00 87.49 ? 282 ARG C CD 1 ATOM 1740 N NE . ARG A 1 217 ? -124.612 -140.894 184.031 1.00 90.78 ? 282 ARG C NE 1 ATOM 1741 C CZ . ARG A 1 217 ? -123.359 -140.458 183.993 1.00 97.08 ? 282 ARG C CZ 1 ATOM 1742 N NH1 . ARG A 1 217 ? -122.605 -140.519 185.086 1.00 94.77 ? 282 ARG C NH1 1 ATOM 1743 N NH2 . ARG A 1 217 ? -122.862 -139.958 182.867 1.00 108.83 ? 282 ARG C NH2 1 ATOM 1744 N N . GLY A 1 218 ? -127.393 -140.464 188.949 1.00 86.05 ? 283 GLY C N 1 ATOM 1745 C CA . GLY A 1 218 ? -127.700 -139.135 189.427 1.00 81.97 ? 283 GLY C CA 1 ATOM 1746 C C . GLY A 1 218 ? -126.568 -138.566 190.250 1.00 84.28 ? 283 GLY C C 1 ATOM 1747 O O . GLY A 1 218 ? -126.121 -137.434 190.017 1.00 83.26 ? 283 GLY C O 1 ATOM 1748 N N . LEU A 1 219 ? -126.096 -139.367 191.202 1.00 85.41 ? 284 LEU C N 1 ATOM 1749 C CA . LEU A 1 219 ? -125.131 -138.889 192.182 1.00 86.02 ? 284 LEU C CA 1 ATOM 1750 C C . LEU A 1 219 ? -123.718 -138.865 191.613 1.00 85.54 ? 284 LEU C C 1 ATOM 1751 O O . LEU A 1 219 ? -122.832 -138.240 192.185 1.00 85.69 ? 284 LEU C O 1 ATOM 1752 C CB . LEU A 1 219 ? -125.192 -139.738 193.455 1.00 80.61 ? 284 LEU C CB 1 ATOM 1753 C CG . LEU A 1 219 ? -126.418 -139.499 194.344 1.00 79.17 ? 284 LEU C CG 1 ATOM 1754 C CD1 . LEU A 1 219 ? -126.516 -140.538 195.441 1.00 78.92 ? 284 LEU C CD1 1 ATOM 1755 C CD2 . LEU A 1 219 ? -126.383 -138.111 194.951 1.00 81.22 ? 284 LEU C CD2 1 ATOM 1756 N N . THR A 1 220 ? -123.510 -139.537 190.486 1.00 82.29 ? 285 THR C N 1 ATOM 1757 C CA . THR A 1 220 ? -122.226 -139.463 189.791 1.00 84.28 ? 285 THR C CA 1 ATOM 1758 C C . THR A 1 220 ? -122.108 -138.278 188.820 1.00 87.55 ? 285 THR C C 1 ATOM 1759 O O . THR A 1 220 ? -121.044 -138.046 188.241 1.00 90.64 ? 285 THR C O 1 ATOM 1760 C CB . THR A 1 220 ? -121.942 -140.741 189.009 1.00 80.29 ? 285 THR C CB 1 ATOM 1761 O OG1 . THR A 1 220 ? -122.974 -140.953 188.039 1.00 87.76 ? 285 THR C OG1 1 ATOM 1762 C CG2 . THR A 1 220 ? -121.883 -141.914 189.954 1.00 82.07 ? 285 THR C CG2 1 ATOM 1763 N N . LEU A 1 221 ? -123.199 -137.545 188.618 1.00 89.77 ? 286 LEU C N 1 ATOM 1764 C CA . LEU A 1 221 ? -123.202 -136.407 187.690 1.00 88.74 ? 286 LEU C CA 1 ATOM 1765 C C . LEU A 1 221 ? -122.471 -135.182 188.241 1.00 85.47 ? 286 LEU C C 1 ATOM 1766 O O . LEU A 1 221 ? -122.512 -134.922 189.449 1.00 84.98 ? 286 LEU C O 1 ATOM 1767 C CB . LEU A 1 221 ? -124.638 -136.023 187.351 1.00 86.38 ? 286 LEU C CB 1 ATOM 1768 C CG . LEU A 1 221 ? -125.382 -136.953 186.411 1.00 85.52 ? 286 LEU C CG 1 ATOM 1769 C CD1 . LEU A 1 221 ? -126.810 -136.505 186.349 1.00 84.58 ? 286 LEU C CD1 1 ATOM 1770 C CD2 . LEU A 1 221 ? -124.748 -136.916 185.034 1.00 82.97 ? 286 LEU C CD2 1 ATOM 1771 N N . PRO A 1 222 ? -121.802 -134.419 187.362 1.00 81.63 ? 287 PRO C N 1 ATOM 1772 C CA . PRO A 1 222 ? -121.270 -133.159 187.893 1.00 77.04 ? 287 PRO C CA 1 ATOM 1773 C C . PRO A 1 222 ? -122.409 -132.294 188.402 1.00 84.50 ? 287 PRO C C 1 ATOM 1774 O O . PRO A 1 222 ? -123.458 -132.231 187.757 1.00 90.04 ? 287 PRO C O 1 ATOM 1775 C CB . PRO A 1 222 ? -120.575 -132.515 186.687 1.00 71.23 ? 287 PRO C CB 1 ATOM 1776 C CG . PRO A 1 222 ? -121.061 -133.281 185.483 1.00 74.63 ? 287 PRO C CG 1 ATOM 1777 C CD . PRO A 1 222 ? -121.401 -134.660 185.966 1.00 77.56 ? 287 PRO C CD 1 ATOM 1778 N N . GLY A 1 223 ? -122.204 -131.616 189.520 1.00 82.64 ? 288 GLY C N 1 ATOM 1779 C CA . GLY A 1 223 ? -123.225 -130.759 190.086 1.00 79.14 ? 288 GLY C CA 1 ATOM 1780 C C . GLY A 1 223 ? -124.257 -131.490 190.932 1.00 84.66 ? 288 GLY C C 1 ATOM 1781 O O . GLY A 1 223 ? -125.155 -130.856 191.507 1.00 85.48 ? 288 GLY C O 1 ATOM 1782 N N . SER A 1 224 ? -124.140 -132.814 191.036 1.00 80.83 ? 289 SER C N 1 ATOM 1783 C CA . SER A 1 224 ? -125.143 -133.568 191.784 1.00 81.89 ? 289 SER C CA 1 ATOM 1784 C C . SER A 1 224 ? -125.186 -133.192 193.267 1.00 79.77 ? 289 SER C C 1 ATOM 1785 O O . SER A 1 224 ? -126.257 -133.154 193.852 1.00 82.52 ? 289 SER C O 1 ATOM 1786 C CB . SER A 1 224 ? -124.918 -135.082 191.629 1.00 85.47 ? 289 SER C CB 1 ATOM 1787 O OG . SER A 1 224 ? -123.683 -135.477 192.170 1.00 89.69 ? 289 SER C OG 1 ATOM 1788 N N . PHE A 1 225 ? -124.042 -132.907 193.877 1.00 83.37 ? 290 PHE C N 1 ATOM 1789 C CA . PHE A 1 225 ? -124.057 -132.488 195.273 1.00 79.64 ? 290 PHE C CA 1 ATOM 1790 C C . PHE A 1 225 ? -124.736 -131.135 195.410 1.00 81.19 ? 290 PHE C C 1 ATOM 1791 O O . PHE A 1 225 ? -125.344 -130.847 196.432 1.00 85.24 ? 290 PHE C O 1 ATOM 1792 C CB . PHE A 1 225 ? -122.641 -132.440 195.881 1.00 80.73 ? 290 PHE C CB 1 ATOM 1793 C CG . PHE A 1 225 ? -122.624 -132.076 197.356 1.00 86.22 ? 290 PHE C CG 1 ATOM 1794 C CD1 . PHE A 1 225 ? -123.057 -132.982 198.321 1.00 88.38 ? 290 PHE C CD1 1 ATOM 1795 C CD2 . PHE A 1 225 ? -122.185 -130.823 197.775 1.00 93.63 ? 290 PHE C CD2 1 ATOM 1796 C CE1 . PHE A 1 225 ? -123.058 -132.643 199.667 1.00 87.98 ? 290 PHE C CE1 1 ATOM 1797 C CE2 . PHE A 1 225 ? -122.179 -130.479 199.121 1.00 82.34 ? 290 PHE C CE2 1 ATOM 1798 C CZ . PHE A 1 225 ? -122.619 -131.389 200.063 1.00 89.04 ? 290 PHE C CZ 1 ATOM 1799 N N . LEU A 1 226 ? -124.634 -130.299 194.385 1.00 83.52 ? 291 LEU C N 1 ATOM 1800 C CA . LEU A 1 226 ? -125.280 -128.999 194.451 1.00 84.63 ? 291 LEU C CA 1 ATOM 1801 C C . LEU A 1 226 ? -126.789 -129.198 194.538 1.00 83.58 ? 291 LEU C C 1 ATOM 1802 O O . LEU A 1 226 ? -127.500 -128.440 195.209 1.00 82.21 ? 291 LEU C O 1 ATOM 1803 C CB . LEU A 1 226 ? -124.915 -128.139 193.236 1.00 83.34 ? 291 LEU C CB 1 ATOM 1804 C CG . LEU A 1 226 ? -125.692 -126.823 193.054 1.00 84.59 ? 291 LEU C CG 1 ATOM 1805 C CD1 . LEU A 1 226 ? -125.496 -125.871 194.231 1.00 71.94 ? 291 LEU C CD1 1 ATOM 1806 C CD2 . LEU A 1 226 ? -125.314 -126.148 191.729 1.00 87.12 ? 291 LEU C CD2 1 ATOM 1807 N N . GLY A 1 227 ? -127.270 -130.251 193.886 1.00 80.83 ? 292 GLY C N 1 ATOM 1808 C CA . GLY A 1 227 ? -128.692 -130.533 193.881 1.00 79.00 ? 292 GLY C CA 1 ATOM 1809 C C . GLY A 1 227 ? -129.136 -130.983 195.252 1.00 80.44 ? 292 GLY C C 1 ATOM 1810 O O . GLY A 1 227 ? -130.129 -130.492 195.800 1.00 82.93 ? 292 GLY C O 1 ATOM 1811 N N . ILE A 1 228 ? -128.353 -131.874 195.843 1.00 76.86 ? 293 ILE C N 1 ATOM 1812 C CA . ILE A 1 228 ? -128.696 -132.390 197.149 1.00 75.62 ? 293 ILE C CA 1 ATOM 1813 C C . ILE A 1 228 ? -128.753 -131.239 198.146 1.00 80.22 ? 293 ILE C C 1 ATOM 1814 O O . ILE A 1 228 ? -129.521 -131.281 199.109 1.00 84.65 ? 293 ILE C O 1 ATOM 1815 C CB . ILE A 1 228 ? -127.704 -133.445 197.603 1.00 73.82 ? 293 ILE C CB 1 ATOM 1816 C CG1 . ILE A 1 228 ? -127.685 -134.594 196.598 1.00 80.25 ? 293 ILE C CG1 1 ATOM 1817 C CG2 . ILE A 1 228 ? -128.100 -133.987 198.950 1.00 81.92 ? 293 ILE C CG2 1 ATOM 1818 C CD1 . ILE A 1 228 ? -129.016 -135.282 196.443 1.00 79.84 ? 293 ILE C CD1 1 ATOM 1819 N N . GLN A 1 229 ? -127.966 -130.199 197.896 1.00 81.35 ? 294 GLN C N 1 ATOM 1820 C CA . GLN A 1 229 ? -127.959 -129.020 198.758 1.00 81.62 ? 294 GLN C CA 1 ATOM 1821 C C . GLN A 1 229 ? -129.282 -128.263 198.708 1.00 82.83 ? 294 GLN C C 1 ATOM 1822 O O . GLN A 1 229 ? -129.796 -127.823 199.738 1.00 80.43 ? 294 GLN C O 1 ATOM 1823 C CB . GLN A 1 229 ? -126.839 -128.073 198.357 1.00 87.54 ? 294 GLN C CB 1 ATOM 1824 C CG . GLN A 1 229 ? -125.468 -128.678 198.339 1.00 87.65 ? 294 GLN C CG 1 ATOM 1825 C CD . GLN A 1 229 ? -124.393 -127.649 198.608 1.00 90.81 ? 294 GLN C CD 1 ATOM 1826 O OE1 . GLN A 1 229 ? -123.649 -127.762 199.578 1.00 98.32 ? 294 GLN C OE1 1 ATOM 1827 N NE2 . GLN A 1 229 ? -124.291 -126.647 197.734 1.00 90.40 ? 294 GLN C NE2 1 ATOM 1828 N N . TYR A 1 230 ? -129.814 -128.090 197.500 1.00 81.45 ? 295 TYR C N 1 ATOM 1829 C CA . TYR A 1 230 ? -131.102 -127.435 197.318 1.00 76.74 ? 295 TYR C CA 1 ATOM 1830 C C . TYR A 1 230 ? -132.217 -128.285 197.897 1.00 76.11 ? 295 TYR C C 1 ATOM 1831 O O . TYR A 1 230 ? -133.234 -127.779 198.367 1.00 72.64 ? 295 TYR C O 1 ATOM 1832 C CB . TYR A 1 230 ? -131.358 -127.175 195.846 1.00 75.59 ? 295 TYR C CB 1 ATOM 1833 C CG . TYR A 1 230 ? -130.575 -126.012 195.283 1.00 80.18 ? 295 TYR C CG 1 ATOM 1834 C CD1 . TYR A 1 230 ? -130.762 -124.720 195.784 1.00 72.98 ? 295 TYR C CD1 1 ATOM 1835 C CD2 . TYR A 1 230 ? -129.672 -126.194 194.232 1.00 77.62 ? 295 TYR C CD2 1 ATOM 1836 C CE1 . TYR A 1 230 ? -130.060 -123.652 195.270 1.00 71.46 ? 295 TYR C CE1 1 ATOM 1837 C CE2 . TYR A 1 230 ? -128.966 -125.127 193.708 1.00 78.56 ? 295 TYR C CE2 1 ATOM 1838 C CZ . TYR A 1 230 ? -129.164 -123.860 194.233 1.00 79.98 ? 295 TYR C CZ 1 ATOM 1839 O OH . TYR A 1 230 ? -128.462 -122.796 193.706 1.00 87.84 ? 295 TYR C OH 1 ATOM 1840 N N . TYR A 1 231 ? -132.007 -129.596 197.850 1.00 79.17 ? 296 TYR C N 1 ATOM 1841 C CA . TYR A 1 231 ? -133.005 -130.543 198.315 1.00 77.17 ? 296 TYR C CA 1 ATOM 1842 C C . TYR A 1 231 ? -133.131 -130.465 199.828 1.00 76.92 ? 296 TYR C C 1 ATOM 1843 O O . TYR A 1 231 ? -134.223 -130.252 200.350 1.00 77.47 ? 296 TYR C O 1 ATOM 1844 C CB . TYR A 1 231 ? -132.625 -131.963 197.865 1.00 76.66 ? 296 TYR C CB 1 ATOM 1845 C CG . TYR A 1 231 ? -133.493 -133.096 198.383 1.00 72.82 ? 296 TYR C CG 1 ATOM 1846 C CD1 . TYR A 1 231 ? -134.747 -132.858 198.931 1.00 76.35 ? 296 TYR C CD1 1 ATOM 1847 C CD2 . TYR A 1 231 ? -133.063 -134.418 198.291 1.00 73.54 ? 296 TYR C CD2 1 ATOM 1848 C CE1 . TYR A 1 231 ? -135.539 -133.907 199.396 1.00 76.34 ? 296 TYR C CE1 1 ATOM 1849 C CE2 . TYR A 1 231 ? -133.847 -135.469 198.744 1.00 72.18 ? 296 TYR C CE2 1 ATOM 1850 C CZ . TYR A 1 231 ? -135.083 -135.207 199.299 1.00 72.96 ? 296 TYR C CZ 1 ATOM 1851 O OH . TYR A 1 231 ? -135.855 -136.258 199.752 1.00 71.58 ? 296 TYR C OH 1 ATOM 1852 N N . LEU A 1 232 ? -132.005 -130.593 200.525 1.00 74.36 ? 297 LEU C N 1 ATOM 1853 C CA . LEU A 1 232 ? -132.052 -130.880 201.950 1.00 77.32 ? 297 LEU C CA 1 ATOM 1854 C C . LEU A 1 232 ? -131.501 -129.811 202.903 1.00 81.81 ? 297 LEU C C 1 ATOM 1855 O O . LEU A 1 232 ? -131.640 -129.957 204.116 1.00 81.87 ? 297 LEU C O 1 ATOM 1856 C CB . LEU A 1 232 ? -131.326 -132.192 202.205 1.00 75.37 ? 297 LEU C CB 1 ATOM 1857 C CG . LEU A 1 232 ? -132.099 -133.363 201.612 1.00 79.65 ? 297 LEU C CG 1 ATOM 1858 C CD1 . LEU A 1 232 ? -131.333 -134.692 201.755 1.00 76.13 ? 297 LEU C CD1 1 ATOM 1859 C CD2 . LEU A 1 232 ? -133.456 -133.440 202.282 1.00 75.29 ? 297 LEU C CD2 1 ATOM 1860 N N . THR A 1 233 ? -130.922 -128.728 202.393 1.00 81.19 ? 298 THR C N 1 ATOM 1861 C CA . THR A 1 233 ? -130.277 -127.786 203.300 1.00 81.01 ? 298 THR C CA 1 ATOM 1862 C C . THR A 1 233 ? -131.322 -127.138 204.204 1.00 80.44 ? 298 THR C C 1 ATOM 1863 O O . THR A 1 233 ? -132.240 -126.458 203.737 1.00 79.59 ? 298 THR C O 1 ATOM 1864 C CB . THR A 1 233 ? -129.499 -126.704 202.519 1.00 81.86 ? 298 THR C CB 1 ATOM 1865 O OG1 . THR A 1 233 ? -128.470 -127.328 201.736 1.00 84.60 ? 298 THR C OG1 1 ATOM 1866 C CG2 . THR A 1 233 ? -128.864 -125.696 203.461 1.00 74.86 ? 298 THR C CG2 1 ATOM 1867 N N . PRO A 1 234 ? -131.141 -127.308 205.518 1.00 79.52 ? 299 PRO C N 1 ATOM 1868 C CA . PRO A 1 234 ? -132.143 -126.896 206.502 1.00 82.40 ? 299 PRO C CA 1 ATOM 1869 C C . PRO A 1 234 ? -132.341 -125.400 206.548 1.00 83.61 ? 299 PRO C C 1 ATOM 1870 O O . PRO A 1 234 ? -131.402 -124.643 206.339 1.00 84.54 ? 299 PRO C O 1 ATOM 1871 C CB . PRO A 1 234 ? -131.574 -127.418 207.834 1.00 80.06 ? 299 PRO C CB 1 ATOM 1872 C CG . PRO A 1 234 ? -130.150 -127.729 207.564 1.00 87.46 ? 299 PRO C CG 1 ATOM 1873 C CD . PRO A 1 234 ? -130.057 -128.095 206.122 1.00 80.47 ? 299 PRO C CD 1 ATOM 1874 N N . ASN A 1 235 ? -133.578 -125.003 206.826 1.00 85.74 ? 300 ASN C N 1 ATOM 1875 C CA . ASN A 1 235 ? -133.940 -123.618 207.069 1.00 81.64 ? 300 ASN C CA 1 ATOM 1876 C C . ASN A 1 235 ? -135.218 -123.610 207.908 1.00 90.77 ? 300 ASN C C 1 ATOM 1877 O O . ASN A 1 235 ? -136.334 -123.587 207.375 1.00 92.84 ? 300 ASN C O 1 ATOM 1878 C CB . ASN A 1 235 ? -134.123 -122.865 205.754 1.00 84.73 ? 300 ASN C CB 1 ATOM 1879 C CG . ASN A 1 235 ? -134.527 -121.411 205.958 1.00 99.65 ? 300 ASN C CG 1 ATOM 1880 O OD1 . ASN A 1 235 ? -134.765 -120.961 207.088 1.00 99.10 ? 300 ASN C OD1 1 ATOM 1881 N ND2 . ASN A 1 235 ? -134.627 -120.668 204.851 1.00 95.32 ? 300 ASN C ND2 1 ATOM 1882 N N . PHE A 1 236 ? -135.046 -123.599 209.228 1.00 93.10 ? 301 PHE C N 1 ATOM 1883 C CA . PHE A 1 236 ? -136.146 -123.828 210.161 1.00 86.95 ? 301 PHE C CA 1 ATOM 1884 C C . PHE A 1 236 ? -137.067 -122.628 210.261 1.00 92.25 ? 301 PHE C C 1 ATOM 1885 O O . PHE A 1 236 ? -138.095 -122.685 210.936 1.00 95.42 ? 301 PHE C O 1 ATOM 1886 C CB . PHE A 1 236 ? -135.605 -124.201 211.534 1.00 80.10 ? 301 PHE C CB 1 ATOM 1887 C CG . PHE A 1 236 ? -134.899 -125.519 211.555 1.00 85.69 ? 301 PHE C CG 1 ATOM 1888 C CD1 . PHE A 1 236 ? -135.551 -126.664 211.991 1.00 82.13 ? 301 PHE C CD1 1 ATOM 1889 C CD2 . PHE A 1 236 ? -133.590 -125.620 211.109 1.00 87.78 ? 301 PHE C CD2 1 ATOM 1890 C CE1 . PHE A 1 236 ? -134.900 -127.890 212.002 1.00 88.14 ? 301 PHE C CE1 1 ATOM 1891 C CE2 . PHE A 1 236 ? -132.927 -126.843 211.114 1.00 88.86 ? 301 PHE C CE2 1 ATOM 1892 C CZ . PHE A 1 236 ? -133.583 -127.981 211.562 1.00 90.81 ? 301 PHE C CZ 1 ATOM 1893 N N . SER A 1 237 ? -136.696 -121.550 209.576 1.00 94.60 ? 302 SER C N 1 ATOM 1894 C CA . SER A 1 237 ? -137.541 -120.372 209.480 1.00 88.66 ? 302 SER C CA 1 ATOM 1895 C C . SER A 1 237 ? -138.877 -120.736 208.851 1.00 97.05 ? 302 SER C C 1 ATOM 1896 O O . SER A 1 237 ? -139.908 -120.138 209.164 1.00 101.25 ? 302 SER C O 1 ATOM 1897 C CB . SER A 1 237 ? -136.852 -119.284 208.661 1.00 92.76 ? 302 SER C CB 1 ATOM 1898 O OG . SER A 1 237 ? -137.814 -118.450 208.034 1.00 104.58 ? 302 SER C OG 1 ATOM 1899 N N . ALA A 1 238 ? -138.857 -121.732 207.972 1.00 100.25 ? 303 ALA C N 1 ATOM 1900 C CA . ALA A 1 238 ? -140.077 -122.203 207.326 1.00 103.42 ? 303 ALA C CA 1 ATOM 1901 C C . ALA A 1 238 ? -141.089 -122.781 208.331 1.00 107.97 ? 303 ALA C C 1 ATOM 1902 O O . ALA A 1 238 ? -142.305 -122.596 208.171 1.00 105.66 ? 303 ALA C O 1 ATOM 1903 C CB . ALA A 1 238 ? -139.738 -123.240 206.261 1.00 92.30 ? 303 ALA C CB 1 ATOM 1904 N N . ILE A 1 239 ? -140.585 -123.430 209.387 1.00 104.51 ? 304 ILE C N 1 ATOM 1905 C CA . ILE A 1 239 ? -141.435 -124.149 210.332 1.00 100.27 ? 304 ILE C CA 1 ATOM 1906 C C . ILE A 1 239 ? -142.420 -123.185 210.994 1.00 102.61 ? 304 ILE C C 1 ATOM 1907 O O . ILE A 1 239 ? -143.505 -123.585 211.423 1.00 99.52 ? 304 ILE C O 1 ATOM 1908 C CB . ILE A 1 239 ? -140.606 -124.881 211.437 1.00 96.99 ? 304 ILE C CB 1 ATOM 1909 C CG1 . ILE A 1 239 ? -139.544 -125.788 210.819 1.00 95.08 ? 304 ILE C CG1 1 ATOM 1910 C CG2 . ILE A 1 239 ? -141.512 -125.726 212.318 1.00 96.20 ? 304 ILE C CG2 1 ATOM 1911 C CD1 . ILE A 1 239 ? -140.081 -126.675 209.714 1.00 95.75 ? 304 ILE C CD1 1 ATOM 1912 N N . TYR A 1 240 ? -142.043 -121.913 211.071 1.00 102.82 ? 305 TYR C N 1 ATOM 1913 C CA . TYR A 1 240 ? -142.898 -120.923 211.710 1.00 102.96 ? 305 TYR C CA 1 ATOM 1914 C C . TYR A 1 240 ? -144.236 -120.776 210.990 1.00 103.73 ? 305 TYR C C 1 ATOM 1915 O O . TYR A 1 240 ? -145.256 -120.560 211.642 1.00 104.55 ? 305 TYR C O 1 ATOM 1916 C CB . TYR A 1 240 ? -142.194 -119.562 211.771 1.00 102.90 ? 305 TYR C CB 1 ATOM 1917 N N . LYS A 1 241 ? -144.230 -120.908 209.660 1.00 106.95 ? 306 LYS C N 1 ATOM 1918 C CA . LYS A 1 241 ? -145.430 -120.665 208.836 1.00 101.34 ? 306 LYS C CA 1 ATOM 1919 C C . LYS A 1 241 ? -146.466 -121.796 208.851 1.00 94.75 ? 306 LYS C C 1 ATOM 1920 O O . LYS A 1 241 ? -146.122 -122.977 208.885 1.00 94.23 ? 306 LYS C O 1 ATOM 1921 C CB . LYS A 1 241 ? -145.022 -120.386 207.385 1.00 95.72 ? 306 LYS C CB 1 ATOM 1922 N N . ALA A 1 242 ? -147.740 -121.417 208.808 1.00 96.49 ? 307 ALA C N 1 ATOM 1923 C CA . ALA A 1 242 ? -148.831 -122.382 208.774 1.00 89.41 ? 307 ALA C CA 1 ATOM 1924 C C . ALA A 1 242 ? -148.879 -123.128 207.456 1.00 87.78 ? 307 ALA C C 1 ATOM 1925 O O . ALA A 1 242 ? -149.237 -124.306 207.411 1.00 89.07 ? 307 ALA C O 1 ATOM 1926 C CB . ALA A 1 242 ? -150.155 -121.693 209.024 1.00 87.93 ? 307 ALA C CB 1 ATOM 1927 N N . GLU A 1 243 ? -148.511 -122.442 206.383 1.00 88.38 ? 308 GLU C N 1 ATOM 1928 C CA . GLU A 1 243 ? -148.628 -123.020 205.056 1.00 88.78 ? 308 GLU C CA 1 ATOM 1929 C C . GLU A 1 243 ? -147.733 -124.256 204.929 1.00 88.14 ? 308 GLU C C 1 ATOM 1930 O O . GLU A 1 243 ? -148.051 -125.192 204.198 1.00 86.83 ? 308 GLU C O 1 ATOM 1931 C CB . GLU A 1 243 ? -148.276 -121.981 203.989 1.00 87.15 ? 308 GLU C CB 1 ATOM 1932 N N . VAL A 1 244 ? -146.619 -124.264 205.653 1.00 86.86 ? 309 VAL C N 1 ATOM 1933 C CA . VAL A 1 244 ? -145.716 -125.404 205.614 1.00 82.10 ? 309 VAL C CA 1 ATOM 1934 C C . VAL A 1 244 ? -146.313 -126.625 206.298 1.00 82.89 ? 309 VAL C C 1 ATOM 1935 O O . VAL A 1 244 ? -146.240 -127.728 205.762 1.00 84.05 ? 309 VAL C O 1 ATOM 1936 C CB . VAL A 1 244 ? -144.379 -125.081 206.266 1.00 85.40 ? 309 VAL C CB 1 ATOM 1937 C CG1 . VAL A 1 244 ? -143.495 -126.330 206.321 1.00 80.97 ? 309 VAL C CG1 1 ATOM 1938 C CG2 . VAL A 1 244 ? -143.687 -123.942 205.509 1.00 87.97 ? 309 VAL C CG2 1 ATOM 1939 N N . TRP A 1 245 ? -146.900 -126.438 207.477 1.00 83.67 ? 310 TRP C N 1 ATOM 1940 C CA . TRP A 1 245 ? -147.556 -127.547 208.162 1.00 79.09 ? 310 TRP C CA 1 ATOM 1941 C C . TRP A 1 245 ? -148.737 -128.090 207.351 1.00 80.48 ? 310 TRP C C 1 ATOM 1942 O O . TRP A 1 245 ? -148.985 -129.295 207.334 1.00 78.34 ? 310 TRP C O 1 ATOM 1943 C CB . TRP A 1 245 ? -148.019 -127.111 209.551 1.00 78.92 ? 310 TRP C CB 1 ATOM 1944 C CG . TRP A 1 245 ? -146.875 -126.818 210.462 1.00 81.81 ? 310 TRP C CG 1 ATOM 1945 C CD1 . TRP A 1 245 ? -146.141 -125.680 210.507 1.00 84.68 ? 310 TRP C CD1 1 ATOM 1946 C CD2 . TRP A 1 245 ? -146.319 -127.695 211.449 1.00 77.62 ? 310 TRP C CD2 1 ATOM 1947 N NE1 . TRP A 1 245 ? -145.154 -125.787 211.467 1.00 85.59 ? 310 TRP C NE1 1 ATOM 1948 C CE2 . TRP A 1 245 ? -145.244 -127.017 212.055 1.00 79.37 ? 310 TRP C CE2 1 ATOM 1949 C CE3 . TRP A 1 245 ? -146.626 -128.986 211.876 1.00 79.28 ? 310 TRP C CE3 1 ATOM 1950 C CZ2 . TRP A 1 245 ? -144.479 -127.581 213.067 1.00 83.01 ? 310 TRP C CZ2 1 ATOM 1951 C CZ3 . TRP A 1 245 ? -145.862 -129.548 212.884 1.00 82.06 ? 310 TRP C CZ3 1 ATOM 1952 C CH2 . TRP A 1 245 ? -144.801 -128.844 213.469 1.00 78.75 ? 310 TRP C CH2 1 ATOM 1953 N N . VAL A 1 246 ? -149.444 -127.204 206.654 1.00 81.48 ? 311 VAL C N 1 ATOM 1954 C CA . VAL A 1 246 ? -150.541 -127.622 205.791 1.00 79.13 ? 311 VAL C CA 1 ATOM 1955 C C . VAL A 1 246 ? -150.038 -128.441 204.608 1.00 83.74 ? 311 VAL C C 1 ATOM 1956 O O . VAL A 1 246 ? -150.700 -129.390 204.165 1.00 81.45 ? 311 VAL C O 1 ATOM 1957 C CB . VAL A 1 246 ? -151.315 -126.419 205.264 1.00 83.12 ? 311 VAL C CB 1 ATOM 1958 C CG1 . VAL A 1 246 ? -152.265 -126.842 204.169 1.00 79.21 ? 311 VAL C CG1 1 ATOM 1959 C CG2 . VAL A 1 246 ? -152.062 -125.745 206.395 1.00 89.01 ? 311 VAL C CG2 1 ATOM 1960 N N . ASP A 1 247 ? -148.865 -128.070 204.099 1.00 84.31 ? 312 ASP C N 1 ATOM 1961 C CA . ASP A 1 247 ? -148.239 -128.805 203.007 1.00 79.84 ? 312 ASP C CA 1 ATOM 1962 C C . ASP A 1 247 ? -147.827 -130.183 203.468 1.00 77.16 ? 312 ASP C C 1 ATOM 1963 O O . ASP A 1 247 ? -147.965 -131.153 202.726 1.00 80.76 ? 312 ASP C O 1 ATOM 1964 C CB . ASP A 1 247 ? -147.011 -128.057 202.474 1.00 83.20 ? 312 ASP C CB 1 ATOM 1965 C CG . ASP A 1 247 ? -147.372 -126.943 201.504 1.00 88.37 ? 312 ASP C CG 1 ATOM 1966 O OD1 . ASP A 1 247 ? -148.503 -126.950 200.967 1.00 86.65 ? 312 ASP C OD1 1 ATOM 1967 O OD2 . ASP A 1 247 ? -146.504 -126.074 201.269 1.00 90.98 ? 312 ASP C OD2 1 ATOM 1968 N N . ALA A 1 248 ? -147.317 -130.263 204.694 1.00 77.77 ? 313 ALA C N 1 ATOM 1969 C CA . ALA A 1 248 ? -146.961 -131.544 205.289 1.00 73.80 ? 313 ALA C CA 1 ATOM 1970 C C . ALA A 1 248 ? -148.207 -132.363 205.589 1.00 77.19 ? 313 ALA C C 1 ATOM 1971 O O . ALA A 1 248 ? -148.241 -133.571 205.347 1.00 75.99 ? 313 ALA C O 1 ATOM 1972 C CB . ALA A 1 248 ? -146.152 -131.345 206.560 1.00 71.10 ? 313 ALA C CB 1 ATOM 1973 N N . ALA A 1 249 ? -149.238 -131.709 206.113 1.00 77.32 ? 314 ALA C N 1 ATOM 1974 C CA . ALA A 1 249 ? -150.443 -132.432 206.461 1.00 75.80 ? 314 ALA C CA 1 ATOM 1975 C C . ALA A 1 249 ? -151.037 -133.038 205.200 1.00 75.75 ? 314 ALA C C 1 ATOM 1976 O O . ALA A 1 249 ? -151.291 -134.243 205.140 1.00 76.39 ? 314 ALA C O 1 ATOM 1977 C CB . ALA A 1 249 ? -151.445 -131.522 207.149 1.00 74.33 ? 314 ALA C CB 1 ATOM 1978 N N . THR A 1 250 ? -151.220 -132.213 204.177 1.00 76.10 ? 315 THR C N 1 ATOM 1979 C CA . THR A 1 250 ? -151.844 -132.696 202.950 1.00 77.33 ? 315 THR C CA 1 ATOM 1980 C C . THR A 1 250 ? -150.999 -133.753 202.228 1.00 71.05 ? 315 THR C C 1 ATOM 1981 O O . THR A 1 250 ? -151.532 -134.708 201.671 1.00 70.91 ? 315 THR C O 1 ATOM 1982 C CB . THR A 1 250 ? -152.135 -131.521 201.998 1.00 76.32 ? 315 THR C CB 1 ATOM 1983 O OG1 . THR A 1 250 ? -150.908 -130.837 201.713 1.00 95.24 ? 315 THR C OG1 1 ATOM 1984 C CG2 . THR A 1 250 ? -153.075 -130.550 202.658 1.00 73.71 ? 315 THR C CG2 1 ATOM 1985 N N . GLN A 1 251 ? -149.682 -133.612 202.268 1.00 71.93 ? 316 GLN C N 1 ATOM 1986 C CA . GLN A 1 251 ? -148.842 -134.558 201.554 1.00 69.53 ? 316 GLN C CA 1 ATOM 1987 C C . GLN A 1 251 ? -148.909 -135.903 202.238 1.00 74.96 ? 316 GLN C C 1 ATOM 1988 O O . GLN A 1 251 ? -149.048 -136.948 201.593 1.00 71.29 ? 316 GLN C O 1 ATOM 1989 C CB . GLN A 1 251 ? -147.400 -134.080 201.490 1.00 69.20 ? 316 GLN C CB 1 ATOM 1990 C CG . GLN A 1 251 ? -146.482 -135.056 200.789 1.00 68.66 ? 316 GLN C CG 1 ATOM 1991 C CD . GLN A 1 251 ? -146.918 -135.382 199.361 1.00 73.45 ? 316 GLN C CD 1 ATOM 1992 O OE1 . GLN A 1 251 ? -147.606 -134.598 198.698 1.00 74.21 ? 316 GLN C OE1 1 ATOM 1993 N NE2 . GLN A 1 251 ? -146.508 -136.551 198.881 1.00 77.16 ? 316 GLN C NE2 1 ATOM 1994 N N . VAL A 1 252 ? -148.850 -135.858 203.566 1.00 77.53 ? 317 VAL C N 1 ATOM 1995 C CA . VAL A 1 252 ? -148.923 -137.058 204.363 1.00 70.66 ? 317 VAL C CA 1 ATOM 1996 C C . VAL A 1 252 ? -150.239 -137.740 204.105 1.00 76.95 ? 317 VAL C C 1 ATOM 1997 O O . VAL A 1 252 ? -150.278 -138.951 203.865 1.00 79.83 ? 317 VAL C O 1 ATOM 1998 C CB . VAL A 1 252 ? -148.809 -136.755 205.837 1.00 71.43 ? 317 VAL C CB 1 ATOM 1999 C CG1 . VAL A 1 252 ? -149.525 -137.823 206.645 1.00 69.87 ? 317 VAL C CG1 1 ATOM 2000 C CG2 . VAL A 1 252 ? -147.358 -136.629 206.213 1.00 73.71 ? 317 VAL C CG2 1 ATOM 2001 N N . PHE A 1 253 ? -151.319 -136.963 204.097 1.00 75.68 ? 318 PHE C N 1 ATOM 2002 C CA . PHE A 1 253 ? -152.631 -137.567 203.932 1.00 72.81 ? 318 PHE C CA 1 ATOM 2003 C C . PHE A 1 253 ? -152.799 -138.221 202.557 1.00 74.90 ? 318 PHE C C 1 ATOM 2004 O O . PHE A 1 253 ? -153.200 -139.378 202.471 1.00 73.54 ? 318 PHE C O 1 ATOM 2005 C CB . PHE A 1 253 ? -153.742 -136.546 204.147 1.00 72.07 ? 318 PHE C CB 1 ATOM 2006 C CG . PHE A 1 253 ? -155.100 -137.095 203.857 1.00 77.18 ? 318 PHE C CG 1 ATOM 2007 C CD1 . PHE A 1 253 ? -155.731 -137.924 204.770 1.00 77.01 ? 318 PHE C CD1 1 ATOM 2008 C CD2 . PHE A 1 253 ? -155.731 -136.822 202.653 1.00 79.34 ? 318 PHE C CD2 1 ATOM 2009 C CE1 . PHE A 1 253 ? -156.975 -138.457 204.500 1.00 77.90 ? 318 PHE C CE1 1 ATOM 2010 C CE2 . PHE A 1 253 ? -156.983 -137.348 202.373 1.00 84.26 ? 318 PHE C CE2 1 ATOM 2011 C CZ . PHE A 1 253 ? -157.608 -138.167 203.299 1.00 83.94 ? 318 PHE C CZ 1 ATOM 2012 N N . PHE A 1 254 ? -152.468 -137.507 201.483 1.00 72.75 ? 319 PHE C N 1 ATOM 2013 C CA . PHE A 1 254 ? -152.682 -138.060 200.147 1.00 69.45 ? 319 PHE C CA 1 ATOM 2014 C C . PHE A 1 254 ? -151.628 -139.097 199.737 1.00 74.73 ? 319 PHE C C 1 ATOM 2015 O O . PHE A 1 254 ? -151.844 -139.871 198.802 1.00 68.37 ? 319 PHE C O 1 ATOM 2016 C CB . PHE A 1 254 ? -152.743 -136.935 199.114 1.00 63.41 ? 319 PHE C CB 1 ATOM 2017 C CG . PHE A 1 254 ? -154.030 -136.151 199.156 1.00 71.64 ? 319 PHE C CG 1 ATOM 2018 C CD1 . PHE A 1 254 ? -155.213 -136.716 198.706 1.00 75.88 ? 319 PHE C CD1 1 ATOM 2019 C CD2 . PHE A 1 254 ? -154.065 -134.862 199.653 1.00 74.57 ? 319 PHE C CD2 1 ATOM 2020 C CE1 . PHE A 1 254 ? -156.411 -136.014 198.751 1.00 78.06 ? 319 PHE C CE1 1 ATOM 2021 C CE2 . PHE A 1 254 ? -155.257 -134.154 199.704 1.00 77.40 ? 319 PHE C CE2 1 ATOM 2022 C CZ . PHE A 1 254 ? -156.435 -134.734 199.249 1.00 81.93 ? 319 PHE C CZ 1 ATOM 2023 N N . SER A 1 255 ? -150.494 -139.132 200.431 1.00 80.08 ? 320 SER C N 1 ATOM 2024 C CA . SER A 1 255 ? -149.440 -140.070 200.053 1.00 75.46 ? 320 SER C CA 1 ATOM 2025 C C . SER A 1 255 ? -149.744 -141.483 200.559 1.00 71.64 ? 320 SER C C 1 ATOM 2026 O O . SER A 1 255 ? -149.690 -142.444 199.801 1.00 74.31 ? 320 SER C O 1 ATOM 2027 C CB . SER A 1 255 ? -148.099 -139.584 200.579 1.00 71.31 ? 320 SER C CB 1 ATOM 2028 O OG . SER A 1 255 ? -147.080 -140.488 200.226 1.00 76.53 ? 320 SER C OG 1 ATOM 2029 N N . LEU A 1 256 ? -150.089 -141.588 201.838 1.00 71.52 ? 321 LEU C N 1 ATOM 2030 C CA . LEU A 1 256 ? -150.670 -142.803 202.401 1.00 71.09 ? 321 LEU C CA 1 ATOM 2031 C C . LEU A 1 256 ? -152.086 -142.883 201.851 1.00 81.84 ? 321 LEU C C 1 ATOM 2032 O O . LEU A 1 256 ? -152.640 -141.870 201.421 1.00 88.03 ? 321 LEU C O 1 ATOM 2033 C CB . LEU A 1 256 ? -150.670 -142.757 203.921 1.00 72.57 ? 321 LEU C CB 1 ATOM 2034 C CG . LEU A 1 256 ? -149.299 -142.723 204.588 1.00 66.09 ? 321 LEU C CG 1 ATOM 2035 C CD1 . LEU A 1 256 ? -149.436 -142.696 206.097 1.00 66.87 ? 321 LEU C CD1 1 ATOM 2036 C CD2 . LEU A 1 256 ? -148.521 -143.936 204.145 1.00 68.45 ? 321 LEU C CD2 1 ATOM 2037 N N . GLY A 1 257 ? -152.695 -144.049 201.799 1.00 74.72 ? 322 GLY C N 1 ATOM 2038 C CA . GLY A 1 257 ? -153.976 -144.062 201.103 1.00 84.68 ? 322 GLY C CA 1 ATOM 2039 C C . GLY A 1 257 ? -155.270 -143.886 201.898 1.00 83.00 ? 322 GLY C C 1 ATOM 2040 O O . GLY A 1 257 ? -156.337 -144.192 201.371 1.00 84.63 ? 322 GLY C O 1 ATOM 2041 N N . PRO A 1 258 ? -155.188 -143.409 203.159 1.00 77.71 ? 323 PRO C N 1 ATOM 2042 C CA . PRO A 1 258 ? -156.248 -143.766 204.108 1.00 78.67 ? 323 PRO C CA 1 ATOM 2043 C C . PRO A 1 258 ? -157.629 -143.249 203.730 1.00 88.65 ? 323 PRO C C 1 ATOM 2044 O O . PRO A 1 258 ? -157.757 -142.130 203.219 1.00 89.04 ? 323 PRO C O 1 ATOM 2045 C CB . PRO A 1 258 ? -155.769 -143.122 205.405 1.00 75.58 ? 323 PRO C CB 1 ATOM 2046 C CG . PRO A 1 258 ? -155.082 -141.896 204.953 1.00 75.78 ? 323 PRO C CG 1 ATOM 2047 C CD . PRO A 1 258 ? -154.407 -142.258 203.639 1.00 75.43 ? 323 PRO C CD 1 ATOM 2048 N N . GLY A 1 259 ? -158.646 -144.071 203.996 1.00 90.77 ? 324 GLY C N 1 ATOM 2049 C CA . GLY A 1 259 ? -160.043 -143.717 203.802 1.00 89.89 ? 324 GLY C CA 1 ATOM 2050 C C . GLY A 1 259 ? -160.600 -143.797 202.389 1.00 89.33 ? 324 GLY C C 1 ATOM 2051 O O . GLY A 1 259 ? -161.716 -143.332 202.149 1.00 97.36 ? 324 GLY C O 1 ATOM 2052 N N . PHE A 1 260 ? -159.835 -144.354 201.451 1.00 83.87 ? 325 PHE C N 1 ATOM 2053 C CA . PHE A 1 260 ? -160.307 -144.503 200.070 1.00 84.79 ? 325 PHE C CA 1 ATOM 2054 C C . PHE A 1 260 ? -160.992 -145.836 199.861 1.00 87.62 ? 325 PHE C C 1 ATOM 2055 O O . PHE A 1 260 ? -161.462 -146.135 198.754 1.00 84.27 ? 325 PHE C O 1 ATOM 2056 C CB . PHE A 1 260 ? -159.162 -144.378 199.066 1.00 85.98 ? 325 PHE C CB 1 ATOM 2057 C CG . PHE A 1 260 ? -158.543 -142.999 198.998 1.00 92.60 ? 325 PHE C CG 1 ATOM 2058 C CD1 . PHE A 1 260 ? -158.346 -142.246 200.156 1.00 89.68 ? 325 PHE C CD1 1 ATOM 2059 C CD2 . PHE A 1 260 ? -158.143 -142.462 197.772 1.00 91.18 ? 325 PHE C CD2 1 ATOM 2060 C CE1 . PHE A 1 260 ? -157.776 -140.992 200.092 1.00 89.33 ? 325 PHE C CE1 1 ATOM 2061 C CE2 . PHE A 1 260 ? -157.575 -141.213 197.697 1.00 88.48 ? 325 PHE C CE2 1 ATOM 2062 C CZ . PHE A 1 260 ? -157.388 -140.471 198.857 1.00 94.84 ? 325 PHE C CZ 1 ATOM 2063 N N . GLY A 1 261 ? -160.986 -146.657 200.912 1.00 85.39 ? 326 GLY C N 1 ATOM 2064 C CA . GLY A 1 261 ? -161.575 -147.982 200.870 1.00 77.47 ? 326 GLY C CA 1 ATOM 2065 C C . GLY A 1 261 ? -160.644 -148.963 200.183 1.00 81.30 ? 326 GLY C C 1 ATOM 2066 O O . GLY A 1 261 ? -160.982 -150.133 200.003 1.00 88.37 ? 326 GLY C O 1 ATOM 2067 N N . VAL A 1 262 ? -159.474 -148.483 199.774 1.00 77.09 ? 327 VAL C N 1 ATOM 2068 C CA . VAL A 1 262 ? -158.495 -149.335 199.119 1.00 76.75 ? 327 VAL C CA 1 ATOM 2069 C C . VAL A 1 262 ? -157.747 -150.191 200.125 1.00 76.59 ? 327 VAL C C 1 ATOM 2070 O O . VAL A 1 262 ? -157.627 -151.397 199.959 1.00 76.66 ? 327 VAL C O 1 ATOM 2071 C CB . VAL A 1 262 ? -157.490 -148.497 198.321 1.00 74.70 ? 327 VAL C CB 1 ATOM 2072 C CG1 . VAL A 1 262 ? -156.316 -149.359 197.845 1.00 65.40 ? 327 VAL C CG1 1 ATOM 2073 C CG2 . VAL A 1 262 ? -158.195 -147.808 197.169 1.00 79.67 ? 327 VAL C CG2 1 ATOM 2074 N N . LEU A 1 263 ? -157.253 -149.560 201.178 1.00 75.05 ? 328 LEU C N 1 ATOM 2075 C CA . LEU A 1 263 ? -156.580 -150.288 202.229 1.00 76.15 ? 328 LEU C CA 1 ATOM 2076 C C . LEU A 1 263 ? -157.580 -151.218 202.892 1.00 80.47 ? 328 LEU C C 1 ATOM 2077 O O . LEU A 1 263 ? -157.225 -152.302 203.362 1.00 76.83 ? 328 LEU C O 1 ATOM 2078 C CB . LEU A 1 263 ? -155.977 -149.322 203.246 1.00 77.16 ? 328 LEU C CB 1 ATOM 2079 C CG . LEU A 1 263 ? -154.873 -148.432 202.679 1.00 74.98 ? 328 LEU C CG 1 ATOM 2080 C CD1 . LEU A 1 263 ? -154.323 -147.521 203.760 1.00 73.42 ? 328 LEU C CD1 1 ATOM 2081 C CD2 . LEU A 1 263 ? -153.772 -149.292 202.061 1.00 69.85 ? 328 LEU C CD2 1 ATOM 2082 N N . LEU A 1 264 ? -158.838 -150.784 202.901 1.00 79.66 ? 329 LEU C N 1 ATOM 2083 C CA . LEU A 1 264 ? -159.915 -151.532 203.521 1.00 77.74 ? 329 LEU C CA 1 ATOM 2084 C C . LEU A 1 264 ? -160.089 -152.845 202.792 1.00 81.45 ? 329 LEU C C 1 ATOM 2085 O O . LEU A 1 264 ? -160.135 -153.911 203.408 1.00 85.52 ? 329 LEU C O 1 ATOM 2086 C CB . LEU A 1 264 ? -161.216 -150.732 203.484 1.00 80.01 ? 329 LEU C CB 1 ATOM 2087 C CG . LEU A 1 264 ? -162.325 -151.112 204.461 1.00 84.57 ? 329 LEU C CG 1 ATOM 2088 C CD1 . LEU A 1 264 ? -161.989 -150.630 205.875 1.00 77.36 ? 329 LEU C CD1 1 ATOM 2089 C CD2 . LEU A 1 264 ? -163.643 -150.521 203.988 1.00 86.89 ? 329 LEU C CD2 1 ATOM 2090 N N . ALA A 1 265 ? -160.148 -152.771 201.469 1.00 77.69 ? 330 ALA C N 1 ATOM 2091 C CA . ALA A 1 265 ? -160.401 -153.963 200.682 1.00 77.86 ? 330 ALA C CA 1 ATOM 2092 C C . ALA A 1 265 ? -159.224 -154.931 200.783 1.00 80.78 ? 330 ALA C C 1 ATOM 2093 O O . ALA A 1 265 ? -159.406 -156.139 200.916 1.00 84.48 ? 330 ALA C O 1 ATOM 2094 C CB . ALA A 1 265 ? -160.675 -153.595 199.233 1.00 71.56 ? 330 ALA C CB 1 ATOM 2095 N N . TYR A 1 266 ? -158.016 -154.387 200.758 1.00 79.00 ? 331 TYR C N 1 ATOM 2096 C CA . TYR A 1 266 ? -156.818 -155.212 200.754 1.00 81.58 ? 331 TYR C CA 1 ATOM 2097 C C . TYR A 1 266 ? -156.656 -155.955 202.074 1.00 83.10 ? 331 TYR C C 1 ATOM 2098 O O . TYR A 1 266 ? -156.287 -157.130 202.105 1.00 83.46 ? 331 TYR C O 1 ATOM 2099 C CB . TYR A 1 266 ? -155.594 -154.348 200.483 1.00 77.90 ? 331 TYR C CB 1 ATOM 2100 C CG . TYR A 1 266 ? -155.352 -154.083 199.019 1.00 82.81 ? 331 TYR C CG 1 ATOM 2101 C CD1 . TYR A 1 266 ? -155.812 -154.967 198.043 1.00 82.56 ? 331 TYR C CD1 1 ATOM 2102 C CD2 . TYR A 1 266 ? -154.648 -152.957 198.603 1.00 78.76 ? 331 TYR C CD2 1 ATOM 2103 C CE1 . TYR A 1 266 ? -155.571 -154.730 196.689 1.00 78.40 ? 331 TYR C CE1 1 ATOM 2104 C CE2 . TYR A 1 266 ? -154.411 -152.720 197.263 1.00 77.54 ? 331 TYR C CE2 1 ATOM 2105 C CZ . TYR A 1 266 ? -154.867 -153.596 196.309 1.00 80.49 ? 331 TYR C CZ 1 ATOM 2106 O OH . TYR A 1 266 ? -154.603 -153.307 194.982 1.00 81.22 ? 331 TYR C OH 1 ATOM 2107 N N . ALA A 1 267 ? -156.947 -155.264 203.165 1.00 77.52 ? 332 ALA C N 1 ATOM 2108 C CA . ALA A 1 267 ? -156.837 -155.868 204.476 1.00 77.14 ? 332 ALA C CA 1 ATOM 2109 C C . ALA A 1 267 ? -157.966 -156.869 204.701 1.00 80.08 ? 332 ALA C C 1 ATOM 2110 O O . ALA A 1 267 ? -157.862 -157.749 205.557 1.00 78.22 ? 332 ALA C O 1 ATOM 2111 C CB . ALA A 1 267 ? -156.848 -154.803 205.544 1.00 74.78 ? 332 ALA C CB 1 ATOM 2112 N N . SER A 1 268 ? -159.044 -156.733 203.932 1.00 82.36 ? 333 SER C N 1 ATOM 2113 C CA . SER A 1 268 ? -160.218 -157.596 204.103 1.00 83.20 ? 333 SER C CA 1 ATOM 2114 C C . SER A 1 268 ? -159.924 -159.039 203.684 1.00 84.43 ? 333 SER C C 1 ATOM 2115 O O . SER A 1 268 ? -160.672 -159.956 204.023 1.00 86.25 ? 333 SER C O 1 ATOM 2116 C CB . SER A 1 268 ? -161.414 -157.050 203.305 1.00 82.92 ? 333 SER C CB 1 ATOM 2117 O OG . SER A 1 268 ? -161.349 -157.430 201.934 1.00 83.35 ? 333 SER C OG 1 ATOM 2118 N N . TYR A 1 269 ? -158.852 -159.223 202.920 1.00 82.16 ? 334 TYR C N 1 ATOM 2119 C CA . TYR A 1 269 ? -158.415 -160.552 202.514 1.00 80.60 ? 334 TYR C CA 1 ATOM 2120 C C . TYR A 1 269 ? -157.287 -161.077 203.409 1.00 78.59 ? 334 TYR C C 1 ATOM 2121 O O . TYR A 1 269 ? -156.702 -162.124 203.137 1.00 77.86 ? 334 TYR C O 1 ATOM 2122 C CB . TYR A 1 269 ? -157.970 -160.548 201.052 1.00 77.98 ? 334 TYR C CB 1 ATOM 2123 C CG . TYR A 1 269 ? -159.045 -160.065 200.109 1.00 86.13 ? 334 TYR C CG 1 ATOM 2124 C CD1 . TYR A 1 269 ? -160.105 -160.883 199.753 1.00 89.75 ? 334 TYR C CD1 1 ATOM 2125 C CD2 . TYR A 1 269 ? -159.009 -158.780 199.583 1.00 90.14 ? 334 TYR C CD2 1 ATOM 2126 C CE1 . TYR A 1 269 ? -161.095 -160.437 198.900 1.00 91.46 ? 334 TYR C CE1 1 ATOM 2127 C CE2 . TYR A 1 269 ? -159.990 -158.333 198.722 1.00 85.57 ? 334 TYR C CE2 1 ATOM 2128 C CZ . TYR A 1 269 ? -161.029 -159.165 198.382 1.00 90.41 ? 334 TYR C CZ 1 ATOM 2129 O OH . TYR A 1 269 ? -162.015 -158.733 197.525 1.00 93.18 ? 334 TYR C OH 1 ATOM 2130 N N . ASN A 1 270 ? -156.963 -160.335 204.461 1.00 74.88 ? 335 ASN C N 1 ATOM 2131 C CA . ASN A 1 270 ? -156.034 -160.831 205.471 1.00 78.32 ? 335 ASN C CA 1 ATOM 2132 C C . ASN A 1 270 ? -156.609 -161.957 206.325 1.00 78.55 ? 335 ASN C C 1 ATOM 2133 O O . ASN A 1 270 ? -157.826 -162.031 206.555 1.00 78.90 ? 335 ASN C O 1 ATOM 2134 C CB . ASN A 1 270 ? -155.600 -159.700 206.398 1.00 77.50 ? 335 ASN C CB 1 ATOM 2135 C CG . ASN A 1 270 ? -154.649 -158.752 205.743 1.00 76.73 ? 335 ASN C CG 1 ATOM 2136 O OD1 . ASN A 1 270 ? -154.212 -158.974 204.614 1.00 79.22 ? 335 ASN C OD1 1 ATOM 2137 N ND2 . ASN A 1 270 ? -154.295 -157.694 206.454 1.00 75.35 ? 335 ASN C ND2 1 ATOM 2138 N N . LYS A 1 271 ? -155.734 -162.835 206.797 1.00 78.30 ? 336 LYS C N 1 ATOM 2139 C CA . LYS A 1 271 ? -156.125 -163.752 207.860 1.00 76.39 ? 336 LYS C CA 1 ATOM 2140 C C . LYS A 1 271 ? -156.418 -162.925 209.106 1.00 76.31 ? 336 LYS C C 1 ATOM 2141 O O . LYS A 1 271 ? -155.701 -161.964 209.407 1.00 77.62 ? 336 LYS C O 1 ATOM 2142 C CB . LYS A 1 271 ? -155.039 -164.798 208.126 1.00 69.32 ? 336 LYS C CB 1 ATOM 2143 C CG . LYS A 1 271 ? -154.872 -165.794 206.993 1.00 74.26 ? 336 LYS C CG 1 ATOM 2144 C CD . LYS A 1 271 ? -153.773 -166.823 207.265 1.00 88.07 ? 336 LYS C CD 1 ATOM 2145 C CE . LYS A 1 271 ? -153.614 -167.789 206.087 1.00 99.13 ? 336 LYS C CE 1 ATOM 2146 N NZ . LYS A 1 271 ? -154.913 -168.464 205.720 1.00 98.49 ? 336 LYS C NZ 1 ATOM 2147 N N . TYR A 1 272 ? -157.457 -163.316 209.836 1.00 73.99 ? 337 TYR C N 1 ATOM 2148 C CA . TYR A 1 272 ? -158.004 -162.488 210.906 1.00 72.41 ? 337 TYR C CA 1 ATOM 2149 C C . TYR A 1 272 ? -157.011 -162.141 212.010 1.00 75.79 ? 337 TYR C C 1 ATOM 2150 O O . TYR A 1 272 ? -157.058 -161.039 212.564 1.00 79.64 ? 337 TYR C O 1 ATOM 2151 C CB . TYR A 1 272 ? -159.202 -163.198 211.517 1.00 70.28 ? 337 TYR C CB 1 ATOM 2152 C CG . TYR A 1 272 ? -159.936 -162.458 212.612 1.00 71.20 ? 337 TYR C CG 1 ATOM 2153 C CD1 . TYR A 1 272 ? -160.897 -161.509 212.304 1.00 77.53 ? 337 TYR C CD1 1 ATOM 2154 C CD2 . TYR A 1 272 ? -159.708 -162.745 213.952 1.00 69.76 ? 337 TYR C CD2 1 ATOM 2155 C CE1 . TYR A 1 272 ? -161.593 -160.837 213.291 1.00 77.24 ? 337 TYR C CE1 1 ATOM 2156 C CE2 . TYR A 1 272 ? -160.404 -162.087 214.958 1.00 72.66 ? 337 TYR C CE2 1 ATOM 2157 C CZ . TYR A 1 272 ? -161.347 -161.134 214.620 1.00 79.91 ? 337 TYR C CZ 1 ATOM 2158 O OH . TYR A 1 272 ? -162.042 -160.469 215.605 1.00 78.71 ? 337 TYR C OH 1 ATOM 2159 N N . HIS A 1 273 ? -156.109 -163.068 212.322 1.00 75.38 ? 338 HIS C N 1 ATOM 2160 C CA . HIS A 1 273 ? -155.157 -162.872 213.421 1.00 74.63 ? 338 HIS C CA 1 ATOM 2161 C C . HIS A 1 273 ? -153.809 -162.408 212.910 1.00 77.15 ? 338 HIS C C 1 ATOM 2162 O O . HIS A 1 273 ? -152.795 -162.568 213.589 1.00 79.55 ? 338 HIS C O 1 ATOM 2163 C CB . HIS A 1 273 ? -154.997 -164.154 214.244 1.00 74.81 ? 338 HIS C CB 1 ATOM 2164 C CG . HIS A 1 273 ? -156.206 -164.485 215.056 1.00 75.74 ? 338 HIS C CG 1 ATOM 2165 N ND1 . HIS A 1 273 ? -157.086 -165.488 214.708 1.00 77.37 ? 338 HIS C ND1 1 ATOM 2166 C CD2 . HIS A 1 273 ? -156.712 -163.908 216.172 1.00 72.33 ? 338 HIS C CD2 1 ATOM 2167 C CE1 . HIS A 1 273 ? -158.071 -165.529 215.587 1.00 78.91 ? 338 HIS C CE1 1 ATOM 2168 N NE2 . HIS A 1 273 ? -157.868 -164.581 216.486 1.00 80.91 ? 338 HIS C NE2 1 ATOM 2169 N N . ASN A 1 274 ? -153.802 -161.871 211.692 1.00 72.37 ? 339 ASN C N 1 ATOM 2170 C CA . ASN A 1 274 ? -152.614 -161.258 211.131 1.00 71.49 ? 339 ASN C CA 1 ATOM 2171 C C . ASN A 1 274 ? -152.211 -160.017 211.925 1.00 71.89 ? 339 ASN C C 1 ATOM 2172 O O . ASN A 1 274 ? -153.067 -159.290 212.431 1.00 74.41 ? 339 ASN C O 1 ATOM 2173 C CB . ASN A 1 274 ? -152.860 -160.916 209.663 1.00 79.31 ? 339 ASN C CB 1 ATOM 2174 C CG . ASN A 1 274 ? -151.687 -160.195 209.030 1.00 79.21 ? 339 ASN C CG 1 ATOM 2175 O OD1 . ASN A 1 274 ? -150.624 -160.780 208.828 1.00 80.36 ? 339 ASN C OD1 1 ATOM 2176 N ND2 . ASN A 1 274 ? -151.876 -158.917 208.717 1.00 78.14 ? 339 ASN C ND2 1 ATOM 2177 N N . ASN A 1 275 ? -150.913 -159.776 212.055 1.00 74.40 ? 340 ASN C N 1 ATOM 2178 C CA . ASN A 1 275 ? -150.468 -158.602 212.797 1.00 73.23 ? 340 ASN C CA 1 ATOM 2179 C C . ASN A 1 275 ? -150.558 -157.346 211.936 1.00 79.66 ? 340 ASN C C 1 ATOM 2180 O O . ASN A 1 275 ? -149.550 -156.838 211.448 1.00 80.92 ? 340 ASN C O 1 ATOM 2181 C CB . ASN A 1 275 ? -149.049 -158.793 213.304 1.00 71.39 ? 340 ASN C CB 1 ATOM 2182 C CG . ASN A 1 275 ? -148.654 -157.746 214.308 1.00 77.87 ? 340 ASN C CG 1 ATOM 2183 O OD1 . ASN A 1 275 ? -149.353 -156.750 214.476 1.00 78.33 ? 340 ASN C OD1 1 ATOM 2184 N ND2 . ASN A 1 275 ? -147.528 -157.957 214.983 1.00 87.00 ? 340 ASN C ND2 1 ATOM 2185 N N . VAL A 1 276 ? -151.777 -156.843 211.767 1.00 76.76 ? 341 VAL C N 1 ATOM 2186 C CA . VAL A 1 276 ? -152.033 -155.724 210.874 1.00 72.79 ? 341 VAL C CA 1 ATOM 2187 C C . VAL A 1 276 ? -151.287 -154.466 211.334 1.00 74.54 ? 341 VAL C C 1 ATOM 2188 O O . VAL A 1 276 ? -150.907 -153.637 210.518 1.00 78.09 ? 341 VAL C O 1 ATOM 2189 C CB . VAL A 1 276 ? -153.555 -155.436 210.770 1.00 73.03 ? 341 VAL C CB 1 ATOM 2190 C CG1 . VAL A 1 276 ? -154.059 -154.756 212.036 1.00 73.55 ? 341 VAL C CG1 1 ATOM 2191 C CG2 . VAL A 1 276 ? -153.873 -154.588 209.548 1.00 68.46 ? 341 VAL C CG2 1 ATOM 2192 N N . TYR A 1 277 ? -151.063 -154.334 212.635 1.00 73.86 ? 342 TYR C N 1 ATOM 2193 C CA . TYR A 1 277 ? -150.317 -153.193 213.165 1.00 77.77 ? 342 TYR C CA 1 ATOM 2194 C C . TYR A 1 277 ? -148.848 -153.190 212.735 1.00 80.88 ? 342 TYR C C 1 ATOM 2195 O O . TYR A 1 277 ? -148.286 -152.141 212.420 1.00 81.66 ? 342 TYR C O 1 ATOM 2196 C CB . TYR A 1 277 ? -150.399 -153.193 214.685 1.00 75.25 ? 342 TYR C CB 1 ATOM 2197 C CG . TYR A 1 277 ? -149.503 -152.198 215.381 1.00 78.23 ? 342 TYR C CG 1 ATOM 2198 C CD1 . TYR A 1 277 ? -149.791 -150.843 215.366 1.00 80.74 ? 342 TYR C CD1 1 ATOM 2199 C CD2 . TYR A 1 277 ? -148.396 -152.617 216.092 1.00 78.73 ? 342 TYR C CD2 1 ATOM 2200 C CE1 . TYR A 1 277 ? -148.986 -149.933 216.023 1.00 80.17 ? 342 TYR C CE1 1 ATOM 2201 C CE2 . TYR A 1 277 ? -147.589 -151.712 216.762 1.00 79.89 ? 342 TYR C CE2 1 ATOM 2202 C CZ . TYR A 1 277 ? -147.889 -150.375 216.717 1.00 79.37 ? 342 TYR C CZ 1 ATOM 2203 O OH . TYR A 1 277 ? -147.092 -149.464 217.369 1.00 87.27 ? 342 TYR C OH 1 ATOM 2204 N N . LYS A 1 278 ? -148.220 -154.358 212.731 1.00 76.75 ? 343 LYS C N 1 ATOM 2205 C CA . LYS A 1 278 ? -146.851 -154.446 212.258 1.00 78.72 ? 343 LYS C CA 1 ATOM 2206 C C . LYS A 1 278 ? -146.826 -154.117 210.767 1.00 79.79 ? 343 LYS C C 1 ATOM 2207 O O . LYS A 1 278 ? -145.921 -153.439 210.284 1.00 80.38 ? 343 LYS C O 1 ATOM 2208 C CB . LYS A 1 278 ? -146.277 -155.839 212.539 1.00 83.86 ? 343 LYS C CB 1 ATOM 2209 C CG . LYS A 1 278 ? -144.816 -156.019 212.164 1.00 90.37 ? 343 LYS C CG 1 ATOM 2210 C CD . LYS A 1 278 ? -144.260 -157.299 212.781 1.00 99.17 ? 343 LYS C CD 1 ATOM 2211 C CE . LYS A 1 278 ? -142.795 -157.530 212.408 1.00 109.48 ? 343 LYS C CE 1 ATOM 2212 N NZ . LYS A 1 278 ? -142.618 -158.040 211.013 1.00 113.39 ? 343 LYS C NZ 1 ATOM 2213 N N . ASP A 1 279 ? -147.851 -154.567 210.048 1.00 81.69 ? 344 ASP C N 1 ATOM 2214 C CA . ASP A 1 279 ? -147.947 -154.306 208.614 1.00 79.42 ? 344 ASP C CA 1 ATOM 2215 C C . ASP A 1 279 ? -148.161 -152.828 208.314 1.00 75.40 ? 344 ASP C C 1 ATOM 2216 O O . ASP A 1 279 ? -147.627 -152.303 207.349 1.00 80.18 ? 344 ASP C O 1 ATOM 2217 C CB . ASP A 1 279 ? -149.087 -155.121 207.999 1.00 78.94 ? 344 ASP C CB 1 ATOM 2218 C CG . ASP A 1 279 ? -148.837 -156.603 208.068 1.00 83.57 ? 344 ASP C CG 1 ATOM 2219 O OD1 . ASP A 1 279 ? -147.699 -156.990 208.397 1.00 91.29 ? 344 ASP C OD1 1 ATOM 2220 O OD2 . ASP A 1 279 ? -149.768 -157.381 207.780 1.00 88.45 ? 344 ASP C OD2 1 ATOM 2221 N N . ALA A 1 280 ? -148.954 -152.156 209.131 1.00 77.34 ? 345 ALA C N 1 ATOM 2222 C CA . ALA A 1 280 ? -149.212 -150.748 208.910 1.00 71.70 ? 345 ALA C CA 1 ATOM 2223 C C . ALA A 1 280 ? -147.956 -149.913 209.123 1.00 72.59 ? 345 ALA C C 1 ATOM 2224 O O . ALA A 1 280 ? -147.759 -148.927 208.438 1.00 78.03 ? 345 ALA C O 1 ATOM 2225 C CB . ALA A 1 280 ? -150.330 -150.273 209.810 1.00 71.40 ? 345 ALA C CB 1 ATOM 2226 N N . LEU A 1 281 ? -147.089 -150.318 210.045 1.00 76.28 ? 346 LEU C N 1 ATOM 2227 C CA . LEU A 1 281 ? -145.889 -149.539 210.329 1.00 70.14 ? 346 LEU C CA 1 ATOM 2228 C C . LEU A 1 281 ? -144.806 -149.770 209.296 1.00 73.99 ? 346 LEU C C 1 ATOM 2229 O O . LEU A 1 281 ? -144.179 -148.824 208.821 1.00 79.45 ? 346 LEU C O 1 ATOM 2230 C CB . LEU A 1 281 ? -145.332 -149.879 211.704 1.00 68.73 ? 346 LEU C CB 1 ATOM 2231 C CG . LEU A 1 281 ? -146.077 -149.383 212.939 1.00 75.34 ? 346 LEU C CG 1 ATOM 2232 C CD1 . LEU A 1 281 ? -145.337 -149.830 214.182 1.00 73.22 ? 346 LEU C CD1 1 ATOM 2233 C CD2 . LEU A 1 281 ? -146.257 -147.864 212.924 1.00 73.39 ? 346 LEU C CD2 1 ATOM 2234 N N . LEU A 1 282 ? -144.590 -151.032 208.942 1.00 73.23 ? 347 LEU C N 1 ATOM 2235 C CA . LEU A 1 282 ? -143.562 -151.360 207.967 1.00 73.40 ? 347 LEU C CA 1 ATOM 2236 C C . LEU A 1 282 ? -143.905 -150.666 206.662 1.00 78.55 ? 347 LEU C C 1 ATOM 2237 O O . LEU A 1 282 ? -143.064 -150.056 206.001 1.00 82.41 ? 347 LEU C O 1 ATOM 2238 C CB . LEU A 1 282 ? -143.470 -152.878 207.758 1.00 66.85 ? 347 LEU C CB 1 ATOM 2239 C CG . LEU A 1 282 ? -142.710 -153.273 206.490 1.00 78.23 ? 347 LEU C CG 1 ATOM 2240 C CD1 . LEU A 1 282 ? -141.249 -152.815 206.560 1.00 71.99 ? 347 LEU C CD1 1 ATOM 2241 C CD2 . LEU A 1 282 ? -142.804 -154.771 206.172 1.00 73.61 ? 347 LEU C CD2 1 ATOM 2242 N N . THR A 1 283 ? -145.186 -150.719 206.344 1.00 77.31 ? 348 THR C N 1 ATOM 2243 C CA . THR A 1 283 ? -145.695 -150.204 205.099 1.00 73.17 ? 348 THR C CA 1 ATOM 2244 C C . THR A 1 283 ? -145.657 -148.675 205.042 1.00 75.72 ? 348 THR C C 1 ATOM 2245 O O . THR A 1 283 ? -145.258 -148.115 204.021 1.00 75.37 ? 348 THR C O 1 ATOM 2246 C CB . THR A 1 283 ? -147.124 -150.727 204.875 1.00 73.65 ? 348 THR C CB 1 ATOM 2247 O OG1 . THR A 1 283 ? -147.062 -151.888 204.036 1.00 77.55 ? 348 THR C OG1 1 ATOM 2248 C CG2 . THR A 1 283 ? -147.979 -149.700 204.227 1.00 74.45 ? 348 THR C CG2 1 ATOM 2249 N N . SER A 1 284 ? -146.033 -147.998 206.131 1.00 76.91 ? 349 SER C N 1 ATOM 2250 C CA . SER A 1 284 ? -145.976 -146.535 206.156 1.00 72.61 ? 349 SER C CA 1 ATOM 2251 C C . SER A 1 284 ? -144.552 -146.122 205.884 1.00 78.38 ? 349 SER C C 1 ATOM 2252 O O . SER A 1 284 ? -144.291 -145.245 205.049 1.00 79.72 ? 349 SER C O 1 ATOM 2253 C CB . SER A 1 284 ? -146.396 -145.936 207.502 1.00 72.83 ? 349 SER C CB 1 ATOM 2254 O OG . SER A 1 284 ? -147.308 -146.744 208.204 1.00 84.28 ? 349 SER C OG 1 ATOM 2255 N N . PHE A 1 285 ? -143.633 -146.778 206.592 1.00 76.66 ? 350 PHE C N 1 ATOM 2256 C CA . PHE A 1 285 ? -142.239 -146.381 206.576 1.00 78.45 ? 350 PHE C CA 1 ATOM 2257 C C . PHE A 1 285 ? -141.645 -146.472 205.184 1.00 75.70 ? 350 PHE C C 1 ATOM 2258 O O . PHE A 1 285 ? -140.917 -145.572 204.748 1.00 72.93 ? 350 PHE C O 1 ATOM 2259 C CB . PHE A 1 285 ? -141.425 -147.245 207.531 1.00 76.65 ? 350 PHE C CB 1 ATOM 2260 C CG . PHE A 1 285 ? -139.956 -146.972 207.468 1.00 77.01 ? 350 PHE C CG 1 ATOM 2261 C CD1 . PHE A 1 285 ? -139.418 -145.868 208.112 1.00 78.13 ? 350 PHE C CD1 1 ATOM 2262 C CD2 . PHE A 1 285 ? -139.112 -147.807 206.753 1.00 75.79 ? 350 PHE C CD2 1 ATOM 2263 C CE1 . PHE A 1 285 ? -138.061 -145.601 208.049 1.00 81.86 ? 350 PHE C CE1 1 ATOM 2264 C CE2 . PHE A 1 285 ? -137.758 -147.550 206.684 1.00 77.85 ? 350 PHE C CE2 1 ATOM 2265 C CZ . PHE A 1 285 ? -137.228 -146.445 207.338 1.00 81.94 ? 350 PHE C CZ 1 ATOM 2266 N N . ILE A 1 286 ? -141.979 -147.545 204.476 1.00 76.31 ? 351 ILE C N 1 ATOM 2267 C CA . ILE A 1 286 ? -141.457 -147.750 203.128 1.00 75.31 ? 351 ILE C CA 1 ATOM 2268 C C . ILE A 1 286 ? -141.949 -146.665 202.164 1.00 76.15 ? 351 ILE C C 1 ATOM 2269 O O . ILE A 1 286 ? -141.212 -146.217 201.279 1.00 76.07 ? 351 ILE C O 1 ATOM 2270 C CB . ILE A 1 286 ? -141.850 -149.135 202.610 1.00 71.02 ? 351 ILE C CB 1 ATOM 2271 C CG1 . ILE A 1 286 ? -141.076 -150.196 203.392 1.00 76.01 ? 351 ILE C CG1 1 ATOM 2272 C CG2 . ILE A 1 286 ? -141.592 -149.253 201.121 1.00 69.19 ? 351 ILE C CG2 1 ATOM 2273 C CD1 . ILE A 1 286 ? -141.635 -151.583 203.242 1.00 80.48 ? 351 ILE C CD1 1 ATOM 2274 N N . ASN A 1 287 ? -143.180 -146.206 202.375 1.00 74.18 ? 352 ASN C N 1 ATOM 2275 C CA . ASN A 1 287 ? -143.749 -145.171 201.529 1.00 71.03 ? 352 ASN C CA 1 ATOM 2276 C C . ASN A 1 287 ? -142.938 -143.892 201.646 1.00 71.84 ? 352 ASN C C 1 ATOM 2277 O O . ASN A 1 287 ? -142.446 -143.360 200.651 1.00 72.64 ? 352 ASN C O 1 ATOM 2278 C CB . ASN A 1 287 ? -145.214 -144.921 201.914 1.00 76.64 ? 352 ASN C CB 1 ATOM 2279 C CG . ASN A 1 287 ? -145.822 -143.713 201.204 1.00 73.94 ? 352 ASN C CG 1 ATOM 2280 O OD1 . ASN A 1 287 ? -145.678 -143.542 199.993 1.00 73.94 ? 352 ASN C OD1 1 ATOM 2281 N ND2 . ASN A 1 287 ? -146.503 -142.871 201.964 1.00 71.45 ? 352 ASN C ND2 1 ATOM 2282 N N . SER A 1 288 ? -142.770 -143.413 202.871 1.00 71.12 ? 353 SER C N 1 ATOM 2283 C CA . SER A 1 288 ? -142.020 -142.189 203.077 1.00 70.19 ? 353 SER C CA 1 ATOM 2284 C C . SER A 1 288 ? -140.552 -142.350 202.705 1.00 71.83 ? 353 SER C C 1 ATOM 2285 O O . SER A 1 288 ? -139.946 -141.443 202.143 1.00 71.60 ? 353 SER C O 1 ATOM 2286 C CB . SER A 1 288 ? -142.156 -141.722 204.521 1.00 69.08 ? 353 SER C CB 1 ATOM 2287 O OG . SER A 1 288 ? -143.498 -141.356 204.794 1.00 76.37 ? 353 SER C OG 1 ATOM 2288 N N . ALA A 1 289 ? -139.980 -143.512 202.978 1.00 76.64 ? 354 ALA C N 1 ATOM 2289 C CA . ALA A 1 289 ? -138.566 -143.686 202.704 1.00 71.56 ? 354 ALA C CA 1 ATOM 2290 C C . ALA A 1 289 ? -138.345 -143.587 201.202 1.00 71.16 ? 354 ALA C C 1 ATOM 2291 O O . ALA A 1 289 ? -137.339 -143.034 200.739 1.00 72.89 ? 354 ALA C O 1 ATOM 2292 C CB . ALA A 1 289 ? -138.065 -145.015 203.248 1.00 68.78 ? 354 ALA C CB 1 ATOM 2293 N N . THR A 1 290 ? -139.310 -144.087 200.439 1.00 67.62 ? 355 THR C N 1 ATOM 2294 C CA . THR A 1 290 ? -139.213 -144.013 198.991 1.00 72.81 ? 355 THR C CA 1 ATOM 2295 C C . THR A 1 290 ? -139.230 -142.569 198.504 1.00 70.42 ? 355 THR C C 1 ATOM 2296 O O . THR A 1 290 ? -138.515 -142.210 197.577 1.00 67.68 ? 355 THR C O 1 ATOM 2297 C CB . THR A 1 290 ? -140.354 -144.784 198.314 1.00 71.14 ? 355 THR C CB 1 ATOM 2298 O OG1 . THR A 1 290 ? -140.309 -146.159 198.718 1.00 73.74 ? 355 THR C OG1 1 ATOM 2299 C CG2 . THR A 1 290 ? -140.207 -144.706 196.817 1.00 67.07 ? 355 THR C CG2 1 ATOM 2300 N N . SER A 1 291 ? -140.019 -141.728 199.159 1.00 70.67 ? 356 SER C N 1 ATOM 2301 C CA . SER A 1 291 ? -140.049 -140.327 198.778 1.00 70.19 ? 356 SER C CA 1 ATOM 2302 C C . SER A 1 291 ? -138.714 -139.678 199.056 1.00 69.82 ? 356 SER C C 1 ATOM 2303 O O . SER A 1 291 ? -138.226 -138.876 198.266 1.00 75.11 ? 356 SER C O 1 ATOM 2304 C CB . SER A 1 291 ? -141.148 -139.589 199.527 1.00 71.09 ? 356 SER C CB 1 ATOM 2305 O OG . SER A 1 291 ? -142.397 -140.185 199.265 1.00 75.90 ? 356 SER C OG 1 ATOM 2306 N N . PHE A 1 292 ? -138.109 -140.068 200.167 1.00 68.07 ? 357 PHE C N 1 ATOM 2307 C CA . PHE A 1 292 ? -136.854 -139.483 200.593 1.00 70.04 ? 357 PHE C CA 1 ATOM 2308 C C . PHE A 1 292 ? -135.801 -139.807 199.551 1.00 72.14 ? 357 PHE C C 1 ATOM 2309 O O . PHE A 1 292 ? -135.104 -138.915 199.071 1.00 71.21 ? 357 PHE C O 1 ATOM 2310 C CB . PHE A 1 292 ? -136.470 -140.017 201.977 1.00 77.15 ? 357 PHE C CB 1 ATOM 2311 C CG . PHE A 1 292 ? -135.254 -139.361 202.577 1.00 79.26 ? 357 PHE C CG 1 ATOM 2312 C CD1 . PHE A 1 292 ? -135.302 -138.041 203.008 1.00 75.34 ? 357 PHE C CD1 1 ATOM 2313 C CD2 . PHE A 1 292 ? -134.070 -140.078 202.736 1.00 76.08 ? 357 PHE C CD2 1 ATOM 2314 C CE1 . PHE A 1 292 ? -134.186 -137.438 203.568 1.00 76.90 ? 357 PHE C CE1 1 ATOM 2315 C CE2 . PHE A 1 292 ? -132.954 -139.483 203.292 1.00 72.89 ? 357 PHE C CE2 1 ATOM 2316 C CZ . PHE A 1 292 ? -133.014 -138.162 203.714 1.00 75.17 ? 357 PHE C CZ 1 ATOM 2317 N N . ILE A 1 293 ? -135.746 -141.083 199.166 1.00 71.46 ? 358 ILE C N 1 ATOM 2318 C CA . ILE A 1 293 ? -134.797 -141.573 198.173 1.00 68.56 ? 358 ILE C CA 1 ATOM 2319 C C . ILE A 1 293 ? -134.973 -140.894 196.832 1.00 70.20 ? 358 ILE C C 1 ATOM 2320 O O . ILE A 1 293 ? -134.016 -140.401 196.223 1.00 71.18 ? 358 ILE C O 1 ATOM 2321 C CB . ILE A 1 293 ? -134.954 -143.094 197.939 1.00 70.75 ? 358 ILE C CB 1 ATOM 2322 C CG1 . ILE A 1 293 ? -134.608 -143.883 199.203 1.00 76.35 ? 358 ILE C CG1 1 ATOM 2323 C CG2 . ILE A 1 293 ? -134.090 -143.544 196.781 1.00 66.40 ? 358 ILE C CG2 1 ATOM 2324 C CD1 . ILE A 1 293 ? -133.253 -143.540 199.768 1.00 80.69 ? 358 ILE C CD1 1 ATOM 2325 N N . ALA A 1 294 ? -136.222 -140.859 196.385 1.00 69.80 ? 359 ALA C N 1 ATOM 2326 C CA . ALA A 1 294 ? -136.550 -140.360 195.063 1.00 65.74 ? 359 ALA C CA 1 ATOM 2327 C C . ALA A 1 294 ? -136.134 -138.913 194.964 1.00 70.74 ? 359 ALA C C 1 ATOM 2328 O O . ALA A 1 294 ? -135.812 -138.417 193.881 1.00 66.26 ? 359 ALA C O 1 ATOM 2329 C CB . ALA A 1 294 ? -138.024 -140.511 194.793 1.00 68.64 ? 359 ALA C CB 1 ATOM 2330 N N . GLY A 1 295 ? -136.137 -138.238 196.109 1.00 69.41 ? 360 GLY C N 1 ATOM 2331 C CA . GLY A 1 295 ? -135.752 -136.846 196.147 1.00 70.41 ? 360 GLY C CA 1 ATOM 2332 C C . GLY A 1 295 ? -134.295 -136.721 195.773 1.00 69.44 ? 360 GLY C C 1 ATOM 2333 O O . GLY A 1 295 ? -133.905 -135.801 195.053 1.00 70.57 ? 360 GLY C O 1 ATOM 2334 N N . PHE A 1 296 ? -133.482 -137.662 196.233 1.00 69.84 ? 361 PHE C N 1 ATOM 2335 C CA . PHE A 1 296 ? -132.083 -137.625 195.859 1.00 71.01 ? 361 PHE C CA 1 ATOM 2336 C C . PHE A 1 296 ? -131.964 -137.864 194.367 1.00 70.35 ? 361 PHE C C 1 ATOM 2337 O O . PHE A 1 296 ? -131.161 -137.216 193.694 1.00 70.85 ? 361 PHE C O 1 ATOM 2338 C CB . PHE A 1 296 ? -131.279 -138.664 196.630 1.00 73.31 ? 361 PHE C CB 1 ATOM 2339 C CG . PHE A 1 296 ? -131.101 -138.336 198.090 1.00 73.12 ? 361 PHE C CG 1 ATOM 2340 C CD1 . PHE A 1 296 ? -130.074 -137.508 198.501 1.00 68.44 ? 361 PHE C CD1 1 ATOM 2341 C CD2 . PHE A 1 296 ? -131.954 -138.867 199.048 1.00 71.53 ? 361 PHE C CD2 1 ATOM 2342 C CE1 . PHE A 1 296 ? -129.903 -137.205 199.826 1.00 68.71 ? 361 PHE C CE1 1 ATOM 2343 C CE2 . PHE A 1 296 ? -131.786 -138.568 200.384 1.00 75.72 ? 361 PHE C CE2 1 ATOM 2344 C CZ . PHE A 1 296 ? -130.760 -137.730 200.771 1.00 77.26 ? 361 PHE C CZ 1 ATOM 2345 N N . VAL A 1 297 ? -132.803 -138.757 193.848 1.00 68.65 ? 362 VAL C N 1 ATOM 2346 C CA . VAL A 1 297 ? -132.761 -139.103 192.431 1.00 67.73 ? 362 VAL C CA 1 ATOM 2347 C C . VAL A 1 297 ? -133.043 -137.877 191.567 1.00 72.76 ? 362 VAL C C 1 ATOM 2348 O O . VAL A 1 297 ? -132.387 -137.646 190.547 1.00 72.54 ? 362 VAL C O 1 ATOM 2349 C CB . VAL A 1 297 ? -133.797 -140.189 192.090 1.00 66.50 ? 362 VAL C CB 1 ATOM 2350 C CG1 . VAL A 1 297 ? -133.700 -140.576 190.630 1.00 72.06 ? 362 VAL C CG1 1 ATOM 2351 C CG2 . VAL A 1 297 ? -133.618 -141.394 192.969 1.00 69.50 ? 362 VAL C CG2 1 ATOM 2352 N N . ILE A 1 298 ? -134.014 -137.082 192.009 1.00 71.73 ? 363 ILE C N 1 ATOM 2353 C CA . ILE A 1 298 ? -134.478 -135.936 191.254 1.00 69.76 ? 363 ILE C CA 1 ATOM 2354 C C . ILE A 1 298 ? -133.475 -134.792 191.350 1.00 71.71 ? 363 ILE C C 1 ATOM 2355 O O . ILE A 1 298 ? -133.027 -134.250 190.328 1.00 69.37 ? 363 ILE C O 1 ATOM 2356 C CB . ILE A 1 298 ? -135.878 -135.460 191.762 1.00 68.62 ? 363 ILE C CB 1 ATOM 2357 C CG1 . ILE A 1 298 ? -136.954 -136.453 191.352 1.00 68.98 ? 363 ILE C CG1 1 ATOM 2358 C CG2 . ILE A 1 298 ? -136.232 -134.093 191.210 1.00 63.60 ? 363 ILE C CG2 1 ATOM 2359 C CD1 . ILE A 1 298 ? -137.131 -136.579 189.850 1.00 67.51 ? 363 ILE C CD1 1 ATOM 2360 N N . PHE A 1 299 ? -133.102 -134.439 192.576 1.00 66.16 ? 364 PHE C N 1 ATOM 2361 C CA . PHE A 1 299 ? -132.308 -133.234 192.758 1.00 72.66 ? 364 PHE C CA 1 ATOM 2362 C C . PHE A 1 299 ? -130.827 -133.394 192.433 1.00 75.93 ? 364 PHE C C 1 ATOM 2363 O O . PHE A 1 299 ? -130.132 -132.405 192.208 1.00 76.25 ? 364 PHE C O 1 ATOM 2364 C CB . PHE A 1 299 ? -132.478 -132.708 194.174 1.00 65.49 ? 364 PHE C CB 1 ATOM 2365 C CG . PHE A 1 299 ? -133.719 -131.903 194.352 1.00 70.43 ? 364 PHE C CG 1 ATOM 2366 C CD1 . PHE A 1 299 ? -133.690 -130.532 194.191 1.00 68.09 ? 364 PHE C CD1 1 ATOM 2367 C CD2 . PHE A 1 299 ? -134.934 -132.519 194.617 1.00 73.82 ? 364 PHE C CD2 1 ATOM 2368 C CE1 . PHE A 1 299 ? -134.833 -129.774 194.322 1.00 66.79 ? 364 PHE C CE1 1 ATOM 2369 C CE2 . PHE A 1 299 ? -136.084 -131.772 194.763 1.00 67.92 ? 364 PHE C CE2 1 ATOM 2370 C CZ . PHE A 1 299 ? -136.030 -130.392 194.617 1.00 70.79 ? 364 PHE C CZ 1 ATOM 2371 N N . SER A 1 300 ? -130.339 -134.625 192.394 1.00 74.06 ? 365 SER C N 1 ATOM 2372 C CA . SER A 1 300 ? -128.993 -134.829 191.916 1.00 71.50 ? 365 SER C CA 1 ATOM 2373 C C . SER A 1 300 ? -128.978 -134.384 190.465 1.00 77.36 ? 365 SER C C 1 ATOM 2374 O O . SER A 1 300 ? -128.107 -133.627 190.048 1.00 78.67 ? 365 SER C O 1 ATOM 2375 C CB . SER A 1 300 ? -128.578 -136.285 192.049 1.00 75.02 ? 365 SER C CB 1 ATOM 2376 O OG . SER A 1 300 ? -129.457 -137.124 191.328 1.00 79.70 ? 365 SER C OG 1 ATOM 2377 N N . VAL A 1 301 ? -129.973 -134.846 189.707 1.00 80.32 ? 366 VAL C N 1 ATOM 2378 C CA . VAL A 1 301 ? -130.123 -134.457 188.307 1.00 75.59 ? 366 VAL C CA 1 ATOM 2379 C C . VAL A 1 301 ? -130.478 -132.978 188.160 1.00 76.78 ? 366 VAL C C 1 ATOM 2380 O O . VAL A 1 301 ? -130.018 -132.304 187.233 1.00 74.24 ? 366 VAL C O 1 ATOM 2381 C CB . VAL A 1 301 ? -131.208 -135.275 187.613 1.00 71.60 ? 366 VAL C CB 1 ATOM 2382 C CG1 . VAL A 1 301 ? -131.425 -134.760 186.213 1.00 73.46 ? 366 VAL C CG1 1 ATOM 2383 C CG2 . VAL A 1 301 ? -130.817 -136.725 187.585 1.00 74.16 ? 366 VAL C CG2 1 ATOM 2384 N N . LEU A 1 302 ? -131.296 -132.472 189.079 1.00 74.87 ? 367 LEU C N 1 ATOM 2385 C CA . LEU A 1 302 ? -131.665 -131.065 189.045 1.00 73.19 ? 367 LEU C CA 1 ATOM 2386 C C . LEU A 1 302 ? -130.429 -130.209 189.265 1.00 78.75 ? 367 LEU C C 1 ATOM 2387 O O . LEU A 1 302 ? -130.281 -129.149 188.658 1.00 74.98 ? 367 LEU C O 1 ATOM 2388 C CB . LEU A 1 302 ? -132.719 -130.767 190.106 1.00 71.46 ? 367 LEU C CB 1 ATOM 2389 C CG . LEU A 1 302 ? -134.173 -130.547 189.673 1.00 74.78 ? 367 LEU C CG 1 ATOM 2390 C CD1 . LEU A 1 302 ? -134.630 -131.525 188.604 1.00 70.87 ? 367 LEU C CD1 1 ATOM 2391 C CD2 . LEU A 1 302 ? -135.094 -130.614 190.891 1.00 71.47 ? 367 LEU C CD2 1 ATOM 2392 N N . GLY A 1 303 ? -129.519 -130.696 190.106 1.00 83.46 ? 368 GLY C N 1 ATOM 2393 C CA . GLY A 1 303 ? -128.288 -129.981 190.384 1.00 77.51 ? 368 GLY C CA 1 ATOM 2394 C C . GLY A 1 303 ? -127.390 -130.018 189.170 1.00 80.52 ? 368 GLY C C 1 ATOM 2395 O O . GLY A 1 303 ? -126.688 -129.055 188.868 1.00 83.27 ? 368 GLY C O 1 ATOM 2396 N N . TYR A 1 304 ? -127.406 -131.151 188.476 1.00 80.68 ? 369 TYR C N 1 ATOM 2397 C CA . TYR A 1 304 ? -126.610 -131.316 187.272 1.00 78.77 ? 369 TYR C CA 1 ATOM 2398 C C . TYR A 1 304 ? -127.120 -130.389 186.172 1.00 80.72 ? 369 TYR C C 1 ATOM 2399 O O . TYR A 1 304 ? -126.348 -129.908 185.343 1.00 79.23 ? 369 TYR C O 1 ATOM 2400 C CB . TYR A 1 304 ? -126.636 -132.777 186.819 1.00 77.99 ? 369 TYR C CB 1 ATOM 2401 C CG . TYR A 1 304 ? -126.382 -132.983 185.347 1.00 81.15 ? 369 TYR C CG 1 ATOM 2402 C CD1 . TYR A 1 304 ? -125.091 -132.965 184.825 1.00 83.59 ? 369 TYR C CD1 1 ATOM 2403 C CD2 . TYR A 1 304 ? -127.437 -133.194 184.471 1.00 79.13 ? 369 TYR C CD2 1 ATOM 2404 C CE1 . TYR A 1 304 ? -124.868 -133.154 183.462 1.00 82.00 ? 369 TYR C CE1 1 ATOM 2405 C CE2 . TYR A 1 304 ? -127.219 -133.383 183.112 1.00 75.55 ? 369 TYR C CE2 1 ATOM 2406 C CZ . TYR A 1 304 ? -125.937 -133.363 182.623 1.00 74.87 ? 369 TYR C CZ 1 ATOM 2407 O OH . TYR A 1 304 ? -125.710 -133.545 181.291 1.00 81.97 ? 369 TYR C OH 1 ATOM 2408 N N . MET A 1 305 ? -128.418 -130.106 186.173 1.00 82.39 ? 370 MET C N 1 ATOM 2409 C CA . MET A 1 305 ? -128.939 -129.210 185.155 1.00 82.09 ? 370 MET C CA 1 ATOM 2410 C C . MET A 1 305 ? -128.428 -127.791 185.423 1.00 86.01 ? 370 MET C C 1 ATOM 2411 O O . MET A 1 305 ? -127.988 -127.099 184.499 1.00 87.75 ? 370 MET C O 1 ATOM 2412 C CB . MET A 1 305 ? -130.473 -129.259 185.106 1.00 74.19 ? 370 MET C CB 1 ATOM 2413 C CG . MET A 1 305 ? -131.029 -130.434 184.310 1.00 77.02 ? 370 MET C CG 1 ATOM 2414 S SD . MET A 1 305 ? -132.820 -130.401 183.995 1.00 76.81 ? 370 MET C SD 1 ATOM 2415 C CE . MET A 1 305 ? -133.396 -130.523 185.681 1.00 74.94 ? 370 MET C CE 1 ATOM 2416 N N . ALA A 1 306 ? -128.449 -127.380 186.690 1.00 79.81 ? 371 ALA C N 1 ATOM 2417 C CA . ALA A 1 306 ? -128.064 -126.020 187.064 1.00 78.56 ? 371 ALA C CA 1 ATOM 2418 C C . ALA A 1 306 ? -126.571 -125.759 186.866 1.00 86.90 ? 371 ALA C C 1 ATOM 2419 O O . ALA A 1 306 ? -126.169 -124.691 186.408 1.00 91.35 ? 371 ALA C O 1 ATOM 2420 C CB . ALA A 1 306 ? -128.453 -125.750 188.507 1.00 75.80 ? 371 ALA C CB 1 ATOM 2421 N N . HIS A 1 307 ? -125.757 -126.748 187.213 1.00 90.63 ? 372 HIS C N 1 ATOM 2422 C CA . HIS A 1 307 ? -124.305 -126.658 187.107 1.00 85.93 ? 372 HIS C CA 1 ATOM 2423 C C . HIS A 1 307 ? -123.809 -126.756 185.664 1.00 89.70 ? 372 HIS C C 1 ATOM 2424 O O . HIS A 1 307 ? -122.964 -125.975 185.234 1.00 93.69 ? 372 HIS C O 1 ATOM 2425 C CB . HIS A 1 307 ? -123.678 -127.773 187.953 1.00 92.86 ? 372 HIS C CB 1 ATOM 2426 C CG . HIS A 1 307 ? -122.179 -127.798 187.934 1.00 97.89 ? 372 HIS C CG 1 ATOM 2427 N ND1 . HIS A 1 307 ? -121.408 -126.876 188.614 1.00 90.49 ? 372 HIS C ND1 1 ATOM 2428 C CD2 . HIS A 1 307 ? -121.311 -128.652 187.339 1.00 92.04 ? 372 HIS C CD2 1 ATOM 2429 C CE1 . HIS A 1 307 ? -120.130 -127.154 188.426 1.00 97.64 ? 372 HIS C CE1 1 ATOM 2430 N NE2 . HIS A 1 307 ? -120.044 -128.226 187.655 1.00 94.05 ? 372 HIS C NE2 1 ATOM 2431 N N . THR A 1 308 ? -124.358 -127.713 184.922 1.00 86.99 ? 373 THR C N 1 ATOM 2432 C CA . THR A 1 308 ? -123.880 -128.041 183.585 1.00 84.61 ? 373 THR C CA 1 ATOM 2433 C C . THR A 1 308 ? -124.640 -127.323 182.468 1.00 89.53 ? 373 THR C C 1 ATOM 2434 O O . THR A 1 308 ? -124.036 -126.672 181.624 1.00 93.30 ? 373 THR C O 1 ATOM 2435 C CB . THR A 1 308 ? -123.972 -129.562 183.337 1.00 85.31 ? 373 THR C CB 1 ATOM 2436 O OG1 . THR A 1 308 ? -122.987 -130.234 184.133 1.00 88.50 ? 373 THR C OG1 1 ATOM 2437 C CG2 . THR A 1 308 ? -123.762 -129.894 181.860 1.00 83.06 ? 373 THR C CG2 1 ATOM 2438 N N . LEU A 1 309 ? -125.963 -127.463 182.467 1.00 90.59 ? 374 LEU C N 1 ATOM 2439 C CA . LEU A 1 309 ? -126.810 -127.007 181.366 1.00 82.59 ? 374 LEU C CA 1 ATOM 2440 C C . LEU A 1 309 ? -127.155 -125.523 181.455 1.00 85.05 ? 374 LEU C C 1 ATOM 2441 O O . LEU A 1 309 ? -127.766 -124.961 180.543 1.00 85.84 ? 374 LEU C O 1 ATOM 2442 C CB . LEU A 1 309 ? -128.082 -127.847 181.323 1.00 84.33 ? 374 LEU C CB 1 ATOM 2443 C CG . LEU A 1 309 ? -127.824 -129.358 181.305 1.00 82.82 ? 374 LEU C CG 1 ATOM 2444 C CD1 . LEU A 1 309 ? -129.114 -130.124 181.518 1.00 77.02 ? 374 LEU C CD1 1 ATOM 2445 C CD2 . LEU A 1 309 ? -127.153 -129.790 180.007 1.00 75.26 ? 374 LEU C CD2 1 ATOM 2446 N N . GLY A 1 310 ? -126.771 -124.895 182.561 1.00 89.51 ? 375 GLY C N 1 ATOM 2447 C CA . GLY A 1 310 ? -126.882 -123.451 182.698 1.00 85.10 ? 375 GLY C CA 1 ATOM 2448 C C . GLY A 1 310 ? -128.307 -122.957 182.780 1.00 85.00 ? 375 GLY C C 1 ATOM 2449 O O . GLY A 1 310 ? -128.818 -122.329 181.850 1.00 89.96 ? 375 GLY C O 1 ATOM 2450 N N . VAL A 1 311 ? -128.946 -123.252 183.905 1.00 83.60 ? 376 VAL C N 1 ATOM 2451 C CA . VAL A 1 311 ? -130.341 -122.907 184.122 1.00 78.24 ? 376 VAL C CA 1 ATOM 2452 C C . VAL A 1 311 ? -130.582 -122.701 185.610 1.00 75.73 ? 376 VAL C C 1 ATOM 2453 O O . VAL A 1 311 ? -130.000 -123.399 186.428 1.00 84.05 ? 376 VAL C O 1 ATOM 2454 C CB . VAL A 1 311 ? -131.298 -124.008 183.564 1.00 78.63 ? 376 VAL C CB 1 ATOM 2455 C CG1 . VAL A 1 311 ? -130.796 -125.387 183.883 1.00 73.71 ? 376 VAL C CG1 1 ATOM 2456 C CG2 . VAL A 1 311 ? -132.675 -123.836 184.140 1.00 84.13 ? 376 VAL C CG2 1 ATOM 2457 N N . ARG A 1 312 ? -131.425 -121.742 185.971 1.00 72.73 ? 377 ARG C N 1 ATOM 2458 C CA . ARG A 1 312 ? -131.683 -121.492 187.380 1.00 75.79 ? 377 ARG C CA 1 ATOM 2459 C C . ARG A 1 312 ? -132.354 -122.695 188.040 1.00 79.32 ? 377 ARG C C 1 ATOM 2460 O O . ARG A 1 312 ? -133.255 -123.297 187.464 1.00 80.44 ? 377 ARG C O 1 ATOM 2461 C CB . ARG A 1 312 ? -132.546 -120.244 187.550 1.00 79.21 ? 377 ARG C CB 1 ATOM 2462 C CG . ARG A 1 312 ? -131.956 -119.011 186.906 1.00 85.45 ? 377 ARG C CG 1 ATOM 2463 C CD . ARG A 1 312 ? -132.703 -117.766 187.343 1.00 98.34 ? 377 ARG C CD 1 ATOM 2464 N NE . ARG A 1 312 ? -132.030 -116.543 186.920 1.00 114.01 ? 377 ARG C NE 1 ATOM 2465 C CZ . ARG A 1 312 ? -132.634 -115.364 186.804 1.00 112.34 ? 377 ARG C CZ 1 ATOM 2466 N NH1 . ARG A 1 312 ? -133.934 -115.255 187.076 1.00 105.66 ? 377 ARG C NH1 1 ATOM 2467 N NH2 . ARG A 1 312 ? -131.939 -114.299 186.409 1.00 102.44 ? 377 ARG C NH2 1 ATOM 2468 N N . ILE A 1 313 ? -131.937 -123.033 189.257 1.00 78.14 ? 378 ILE C N 1 ATOM 2469 C CA . ILE A 1 313 ? -132.494 -124.203 189.931 1.00 74.89 ? 378 ILE C CA 1 ATOM 2470 C C . ILE A 1 313 ? -134.000 -124.018 190.124 1.00 79.58 ? 378 ILE C C 1 ATOM 2471 O O . ILE A 1 313 ? -134.784 -124.964 189.977 1.00 79.51 ? 378 ILE C O 1 ATOM 2472 C CB . ILE A 1 313 ? -131.815 -124.450 191.305 1.00 74.86 ? 378 ILE C CB 1 ATOM 2473 C CG1 . ILE A 1 313 ? -132.379 -125.690 192.000 1.00 70.14 ? 378 ILE C CG1 1 ATOM 2474 C CG2 . ILE A 1 313 ? -131.968 -123.241 192.220 1.00 70.76 ? 378 ILE C CG2 1 ATOM 2475 C CD1 . ILE A 1 313 ? -132.253 -126.945 191.185 1.00 75.41 ? 378 ILE C CD1 1 ATOM 2476 N N . GLU A 1 314 ? -134.414 -122.786 190.392 1.00 79.15 ? 379 GLU C N 1 ATOM 2477 C CA . GLU A 1 314 ? -135.820 -122.541 190.656 1.00 82.21 ? 379 GLU C CA 1 ATOM 2478 C C . GLU A 1 314 ? -136.660 -122.794 189.411 1.00 80.28 ? 379 GLU C C 1 ATOM 2479 O O . GLU A 1 314 ? -137.855 -123.050 189.519 1.00 87.48 ? 379 GLU C O 1 ATOM 2480 C CB . GLU A 1 314 ? -136.048 -121.122 191.177 1.00 81.31 ? 379 GLU C CB 1 ATOM 2481 C CG . GLU A 1 314 ? -135.775 -120.031 190.178 1.00 88.87 ? 379 GLU C CG 1 ATOM 2482 C CD . GLU A 1 314 ? -134.381 -119.424 190.328 1.00 96.54 ? 379 GLU C CD 1 ATOM 2483 O OE1 . GLU A 1 314 ? -133.505 -120.059 190.976 1.00 86.04 ? 379 GLU C OE1 1 ATOM 2484 O OE2 . GLU A 1 314 ? -134.170 -118.304 189.796 1.00 109.60 ? 379 GLU C OE2 1 ATOM 2485 N N . ASP A 1 315 ? -136.046 -122.724 188.234 1.00 75.88 ? 380 ASP C N 1 ATOM 2486 C CA . ASP A 1 315 ? -136.789 -122.964 186.994 1.00 78.78 ? 380 ASP C CA 1 ATOM 2487 C C . ASP A 1 315 ? -136.960 -124.445 186.643 1.00 79.36 ? 380 ASP C C 1 ATOM 2488 O O . ASP A 1 315 ? -137.873 -124.800 185.895 1.00 77.70 ? 380 ASP C O 1 ATOM 2489 C CB . ASP A 1 315 ? -136.119 -122.248 185.825 1.00 77.70 ? 380 ASP C CB 1 ATOM 2490 C CG . ASP A 1 315 ? -136.235 -120.739 185.930 1.00 84.83 ? 380 ASP C CG 1 ATOM 2491 O OD1 . ASP A 1 315 ? -137.225 -120.270 186.540 1.00 87.90 ? 380 ASP C OD1 1 ATOM 2492 O OD2 . ASP A 1 315 ? -135.349 -120.024 185.402 1.00 83.90 ? 380 ASP C OD2 1 ATOM 2493 N N . VAL A 1 316 ? -136.086 -125.306 187.168 1.00 73.46 ? 381 VAL C N 1 ATOM 2494 C CA . VAL A 1 316 ? -136.182 -126.738 186.883 1.00 66.38 ? 381 VAL C CA 1 ATOM 2495 C C . VAL A 1 316 ? -136.783 -127.513 188.053 1.00 74.53 ? 381 VAL C C 1 ATOM 2496 O O . VAL A 1 316 ? -137.283 -128.627 187.875 1.00 75.14 ? 381 VAL C O 1 ATOM 2497 C CB . VAL A 1 316 ? -134.820 -127.355 186.547 1.00 67.13 ? 381 VAL C CB 1 ATOM 2498 C CG1 . VAL A 1 316 ? -134.291 -126.801 185.254 1.00 73.12 ? 381 VAL C CG1 1 ATOM 2499 C CG2 . VAL A 1 316 ? -133.818 -127.133 187.673 1.00 68.37 ? 381 VAL C CG2 1 ATOM 2500 N N . ALA A 1 317 ? -136.722 -126.934 189.252 1.00 72.17 ? 382 ALA C N 1 ATOM 2501 C CA . ALA A 1 317 ? -137.242 -127.608 190.430 1.00 67.61 ? 382 ALA C CA 1 ATOM 2502 C C . ALA A 1 317 ? -138.743 -127.378 190.504 1.00 73.28 ? 382 ALA C C 1 ATOM 2503 O O . ALA A 1 317 ? -139.215 -126.336 190.957 1.00 77.18 ? 382 ALA C O 1 ATOM 2504 C CB . ALA A 1 317 ? -136.551 -127.122 191.692 1.00 68.52 ? 382 ALA C CB 1 ATOM 2505 N N . THR A 1 318 ? -139.488 -128.377 190.064 1.00 75.52 ? 383 THR C N 1 ATOM 2506 C CA . THR A 1 318 ? -140.919 -128.241 189.928 1.00 74.49 ? 383 THR C CA 1 ATOM 2507 C C . THR A 1 318 ? -141.659 -129.525 190.293 1.00 71.60 ? 383 THR C C 1 ATOM 2508 O O . THR A 1 318 ? -141.062 -130.590 190.387 1.00 77.25 ? 383 THR C O 1 ATOM 2509 C CB . THR A 1 318 ? -141.273 -127.833 188.502 1.00 71.64 ? 383 THR C CB 1 ATOM 2510 O OG1 . THR A 1 318 ? -142.601 -128.283 188.208 1.00 83.41 ? 383 THR C OG1 1 ATOM 2511 C CG2 . THR A 1 318 ? -140.302 -128.472 187.533 1.00 66.17 ? 383 THR C CG2 1 ATOM 2512 N N . GLU A 1 319 ? -142.964 -129.401 190.506 1.00 70.58 ? 384 GLU C N 1 ATOM 2513 C CA . GLU A 1 319 ? -143.822 -130.516 190.873 1.00 72.95 ? 384 GLU C CA 1 ATOM 2514 C C . GLU A 1 319 ? -144.711 -131.001 189.737 1.00 72.49 ? 384 GLU C C 1 ATOM 2515 O O . GLU A 1 319 ? -144.844 -130.333 188.713 1.00 69.77 ? 384 GLU C O 1 ATOM 2516 C CB . GLU A 1 319 ? -144.700 -130.122 192.040 1.00 71.35 ? 384 GLU C CB 1 ATOM 2517 C CG . GLU A 1 319 ? -145.480 -128.873 191.785 1.00 70.43 ? 384 GLU C CG 1 ATOM 2518 C CD . GLU A 1 319 ? -146.449 -128.590 192.912 1.00 91.77 ? 384 GLU C CD 1 ATOM 2519 O OE1 . GLU A 1 319 ? -146.865 -129.575 193.582 1.00 87.58 ? 384 GLU C OE1 1 ATOM 2520 O OE2 . GLU A 1 319 ? -146.787 -127.396 193.135 1.00 96.39 ? 384 GLU C OE2 1 ATOM 2521 N N . GLY A 1 320 ? -145.326 -132.167 189.930 1.00 67.47 ? 385 GLY C N 1 ATOM 2522 C CA . GLY A 1 320 ? -146.371 -132.637 189.038 1.00 64.42 ? 385 GLY C CA 1 ATOM 2523 C C . GLY A 1 320 ? -145.855 -133.142 187.720 1.00 67.00 ? 385 GLY C C 1 ATOM 2524 O O . GLY A 1 320 ? -144.673 -133.392 187.570 1.00 72.90 ? 385 GLY C O 1 ATOM 2525 N N . PRO A 1 321 ? -146.744 -133.252 186.732 1.00 67.38 ? 386 PRO C N 1 ATOM 2526 C CA . PRO A 1 321 ? -146.383 -133.874 185.455 1.00 68.84 ? 386 PRO C CA 1 ATOM 2527 C C . PRO A 1 321 ? -145.191 -133.188 184.795 1.00 70.23 ? 386 PRO C C 1 ATOM 2528 O O . PRO A 1 321 ? -144.385 -133.858 184.141 1.00 72.88 ? 386 PRO C O 1 ATOM 2529 C CB . PRO A 1 321 ? -147.653 -133.671 184.608 1.00 67.47 ? 386 PRO C CB 1 ATOM 2530 C CG . PRO A 1 321 ? -148.751 -133.722 185.603 1.00 68.88 ? 386 PRO C CG 1 ATOM 2531 C CD . PRO A 1 321 ? -148.200 -133.091 186.873 1.00 69.25 ? 386 PRO C CD 1 ATOM 2532 N N . GLY A 1 322 ? -145.070 -131.880 184.990 1.00 64.36 ? 387 GLY C N 1 ATOM 2533 C CA . GLY A 1 322 ? -144.026 -131.143 184.315 1.00 68.52 ? 387 GLY C CA 1 ATOM 2534 C C . GLY A 1 322 ? -142.646 -131.651 184.693 1.00 73.43 ? 387 GLY C C 1 ATOM 2535 O O . GLY A 1 322 ? -141.728 -131.669 183.867 1.00 73.39 ? 387 GLY C O 1 ATOM 2536 N N . LEU A 1 323 ? -142.497 -132.094 185.937 1.00 71.35 ? 388 LEU C N 1 ATOM 2537 C CA . LEU A 1 323 ? -141.202 -132.573 186.393 1.00 70.97 ? 388 LEU C CA 1 ATOM 2538 C C . LEU A 1 323 ? -140.800 -133.840 185.650 1.00 74.09 ? 388 LEU C C 1 ATOM 2539 O O . LEU A 1 323 ? -139.681 -133.927 185.130 1.00 73.45 ? 388 LEU C O 1 ATOM 2540 C CB . LEU A 1 323 ? -141.220 -132.835 187.902 1.00 69.52 ? 388 LEU C CB 1 ATOM 2541 C CG . LEU A 1 323 ? -140.002 -133.516 188.544 1.00 63.15 ? 388 LEU C CG 1 ATOM 2542 C CD1 . LEU A 1 323 ? -138.752 -132.666 188.490 1.00 63.90 ? 388 LEU C CD1 1 ATOM 2543 C CD2 . LEU A 1 323 ? -140.335 -133.851 189.968 1.00 68.57 ? 388 LEU C CD2 1 ATOM 2544 N N . VAL A 1 324 ? -141.718 -134.805 185.574 1.00 70.98 ? 389 VAL C N 1 ATOM 2545 C CA . VAL A 1 324 ? -141.382 -136.111 185.017 1.00 70.31 ? 389 VAL C CA 1 ATOM 2546 C C . VAL A 1 324 ? -141.523 -136.181 183.505 1.00 66.73 ? 389 VAL C C 1 ATOM 2547 O O . VAL A 1 324 ? -140.837 -136.968 182.862 1.00 70.62 ? 389 VAL C O 1 ATOM 2548 C CB . VAL A 1 324 ? -142.248 -137.241 185.624 1.00 71.88 ? 389 VAL C CB 1 ATOM 2549 C CG1 . VAL A 1 324 ? -141.979 -137.386 187.099 1.00 65.43 ? 389 VAL C CG1 1 ATOM 2550 C CG2 . VAL A 1 324 ? -143.728 -136.994 185.350 1.00 69.83 ? 389 VAL C CG2 1 ATOM 2551 N N . PHE A 1 325 ? -142.415 -135.387 182.929 1.00 64.00 ? 390 PHE C N 1 ATOM 2552 C CA . PHE A 1 325 ? -142.606 -135.455 181.484 1.00 66.56 ? 390 PHE C CA 1 ATOM 2553 C C . PHE A 1 325 ? -141.861 -134.389 180.692 1.00 67.10 ? 390 PHE C C 1 ATOM 2554 O O . PHE A 1 325 ? -141.913 -134.386 179.475 1.00 69.20 ? 390 PHE C O 1 ATOM 2555 C CB . PHE A 1 325 ? -144.091 -135.375 181.156 1.00 69.08 ? 390 PHE C CB 1 ATOM 2556 C CG . PHE A 1 325 ? -144.882 -136.529 181.687 1.00 69.46 ? 390 PHE C CG 1 ATOM 2557 C CD1 . PHE A 1 325 ? -144.539 -137.828 181.346 1.00 63.85 ? 390 PHE C CD1 1 ATOM 2558 C CD2 . PHE A 1 325 ? -145.948 -136.319 182.545 1.00 65.71 ? 390 PHE C CD2 1 ATOM 2559 C CE1 . PHE A 1 325 ? -145.242 -138.891 181.828 1.00 67.33 ? 390 PHE C CE1 1 ATOM 2560 C CE2 . PHE A 1 325 ? -146.661 -137.381 183.035 1.00 67.47 ? 390 PHE C CE2 1 ATOM 2561 C CZ . PHE A 1 325 ? -146.311 -138.673 182.677 1.00 73.96 ? 390 PHE C CZ 1 ATOM 2562 N N . VAL A 1 326 ? -141.179 -133.484 181.384 1.00 71.41 ? 391 VAL C N 1 ATOM 2563 C CA . VAL A 1 326 ? -140.508 -132.376 180.730 1.00 66.12 ? 391 VAL C CA 1 ATOM 2564 C C . VAL A 1 326 ? -139.119 -132.148 181.283 1.00 69.87 ? 391 VAL C C 1 ATOM 2565 O O . VAL A 1 326 ? -138.138 -132.347 180.574 1.00 75.74 ? 391 VAL C O 1 ATOM 2566 C CB . VAL A 1 326 ? -141.317 -131.064 180.854 1.00 66.08 ? 391 VAL C CB 1 ATOM 2567 C CG1 . VAL A 1 326 ? -140.501 -129.891 180.305 1.00 64.67 ? 391 VAL C CG1 1 ATOM 2568 C CG2 . VAL A 1 326 ? -142.632 -131.184 180.121 1.00 60.48 ? 391 VAL C CG2 1 ATOM 2569 N N . VAL A 1 327 ? -139.023 -131.737 182.542 1.00 69.03 ? 392 VAL C N 1 ATOM 2570 C CA . VAL A 1 327 ? -137.722 -131.386 183.089 1.00 69.95 ? 392 VAL C CA 1 ATOM 2571 C C . VAL A 1 327 ? -136.740 -132.552 183.192 1.00 64.92 ? 392 VAL C C 1 ATOM 2572 O O . VAL A 1 327 ? -135.629 -132.460 182.705 1.00 66.89 ? 392 VAL C O 1 ATOM 2573 C CB . VAL A 1 327 ? -137.847 -130.762 184.479 1.00 71.71 ? 392 VAL C CB 1 ATOM 2574 C CG1 . VAL A 1 327 ? -136.476 -130.655 185.076 1.00 65.51 ? 392 VAL C CG1 1 ATOM 2575 C CG2 . VAL A 1 327 ? -138.508 -129.392 184.400 1.00 67.90 ? 392 VAL C CG2 1 ATOM 2576 N N . TYR A 1 328 ? -137.148 -133.641 183.821 1.00 68.26 ? 393 TYR C N 1 ATOM 2577 C CA . TYR A 1 328 ? -136.262 -134.800 183.956 1.00 69.92 ? 393 TYR C CA 1 ATOM 2578 C C . TYR A 1 328 ? -135.837 -135.421 182.621 1.00 71.89 ? 393 TYR C C 1 ATOM 2579 O O . TYR A 1 328 ? -134.666 -135.721 182.418 1.00 72.19 ? 393 TYR C O 1 ATOM 2580 C CB . TYR A 1 328 ? -136.926 -135.869 184.821 1.00 66.24 ? 393 TYR C CB 1 ATOM 2581 C CG . TYR A 1 328 ? -135.929 -136.858 185.339 1.00 69.91 ? 393 TYR C CG 1 ATOM 2582 C CD1 . TYR A 1 328 ? -135.161 -136.579 186.464 1.00 70.52 ? 393 TYR C CD1 1 ATOM 2583 C CD2 . TYR A 1 328 ? -135.736 -138.075 184.697 1.00 75.13 ? 393 TYR C CD2 1 ATOM 2584 C CE1 . TYR A 1 328 ? -134.229 -137.502 186.939 1.00 66.35 ? 393 TYR C CE1 1 ATOM 2585 C CE2 . TYR A 1 328 ? -134.811 -138.991 185.162 1.00 72.97 ? 393 TYR C CE2 1 ATOM 2586 C CZ . TYR A 1 328 ? -134.071 -138.701 186.279 1.00 68.50 ? 393 TYR C CZ 1 ATOM 2587 O OH . TYR A 1 328 ? -133.168 -139.631 186.720 1.00 75.56 ? 393 TYR C OH 1 ATOM 2588 N N . PRO A 1 329 ? -136.795 -135.635 181.709 1.00 71.45 ? 394 PRO C N 1 ATOM 2589 C CA . PRO A 1 329 ? -136.435 -136.118 180.372 1.00 70.80 ? 394 PRO C CA 1 ATOM 2590 C C . PRO A 1 329 ? -135.468 -135.172 179.660 1.00 74.52 ? 394 PRO C C 1 ATOM 2591 O O . PRO A 1 329 ? -134.630 -135.617 178.877 1.00 75.74 ? 394 PRO C O 1 ATOM 2592 C CB . PRO A 1 329 ? -137.771 -136.170 179.645 1.00 66.18 ? 394 PRO C CB 1 ATOM 2593 C CG . PRO A 1 329 ? -138.759 -136.417 180.715 1.00 71.22 ? 394 PRO C CG 1 ATOM 2594 C CD . PRO A 1 329 ? -138.254 -135.651 181.914 1.00 71.38 ? 394 PRO C CD 1 ATOM 2595 N N . ALA A 1 330 ? -135.602 -133.877 179.920 1.00 71.30 ? 395 ALA C N 1 ATOM 2596 C CA . ALA A 1 330 ? -134.668 -132.913 179.372 1.00 69.76 ? 395 ALA C CA 1 ATOM 2597 C C . ALA A 1 330 ? -133.240 -133.228 179.797 1.00 73.60 ? 395 ALA C C 1 ATOM 2598 O O . ALA A 1 330 ? -132.337 -133.256 178.961 1.00 76.56 ? 395 ALA C O 1 ATOM 2599 C CB . ALA A 1 330 ? -135.038 -131.513 179.805 1.00 68.31 ? 395 ALA C CB 1 ATOM 2600 N N . ALA A 1 331 ? -133.043 -133.469 181.095 1.00 74.50 ? 396 ALA C N 1 ATOM 2601 C CA . ALA A 1 331 ? -131.713 -133.740 181.646 1.00 70.97 ? 396 ALA C CA 1 ATOM 2602 C C . ALA A 1 331 ? -131.155 -135.050 181.120 1.00 75.90 ? 396 ALA C C 1 ATOM 2603 O O . ALA A 1 331 ? -129.961 -135.169 180.839 1.00 76.22 ? 396 ALA C O 1 ATOM 2604 C CB . ALA A 1 331 ? -131.768 -133.768 183.163 1.00 64.82 ? 396 ALA C CB 1 ATOM 2605 N N . ILE A 1 332 ? -132.043 -136.024 180.967 1.00 79.36 ? 397 ILE C N 1 ATOM 2606 C CA . ILE A 1 332 ? -131.657 -137.362 180.544 1.00 75.87 ? 397 ILE C CA 1 ATOM 2607 C C . ILE A 1 332 ? -131.042 -137.316 179.156 1.00 77.10 ? 397 ILE C C 1 ATOM 2608 O O . ILE A 1 332 ? -130.059 -137.988 178.877 1.00 83.05 ? 397 ILE C O 1 ATOM 2609 C CB . ILE A 1 332 ? -132.885 -138.309 180.526 1.00 74.37 ? 397 ILE C CB 1 ATOM 2610 C CG1 . ILE A 1 332 ? -133.247 -138.766 181.932 1.00 76.95 ? 397 ILE C CG1 1 ATOM 2611 C CG2 . ILE A 1 332 ? -132.642 -139.493 179.643 1.00 74.25 ? 397 ILE C CG2 1 ATOM 2612 C CD1 . ILE A 1 332 ? -134.576 -139.493 181.961 1.00 77.45 ? 397 ILE C CD1 1 ATOM 2613 N N . ALA A 1 333 ? -131.599 -136.457 178.312 1.00 77.18 ? 398 ALA C N 1 ATOM 2614 C CA . ALA A 1 333 ? -131.254 -136.409 176.898 1.00 77.91 ? 398 ALA C CA 1 ATOM 2615 C C . ALA A 1 333 ? -129.840 -135.897 176.670 1.00 80.19 ? 398 ALA C C 1 ATOM 2616 O O . ALA A 1 333 ? -129.254 -136.125 175.615 1.00 83.16 ? 398 ALA C O 1 ATOM 2617 C CB . ALA A 1 333 ? -132.259 -135.537 176.147 1.00 78.09 ? 398 ALA C CB 1 ATOM 2618 N N . THR A 1 334 ? -129.315 -135.162 177.643 1.00 77.80 ? 399 THR C N 1 ATOM 2619 C CA . THR A 1 334 ? -127.964 -134.636 177.549 1.00 78.00 ? 399 THR C CA 1 ATOM 2620 C C . THR A 1 334 ? -126.917 -135.664 177.990 1.00 80.86 ? 399 THR C C 1 ATOM 2621 O O . THR A 1 334 ? -125.723 -135.489 177.768 1.00 86.90 ? 399 THR C O 1 ATOM 2622 C CB . THR A 1 334 ? -127.821 -133.373 178.395 1.00 75.37 ? 399 THR C CB 1 ATOM 2623 O OG1 . THR A 1 334 ? -127.807 -133.729 179.781 1.00 80.02 ? 399 THR C OG1 1 ATOM 2624 C CG2 . THR A 1 334 ? -128.982 -132.431 178.130 1.00 77.24 ? 399 THR C CG2 1 ATOM 2625 N N . MET A 1 335 ? -127.371 -136.729 178.636 1.00 81.76 ? 400 MET C N 1 ATOM 2626 C CA . MET A 1 335 ? -126.464 -137.741 179.167 1.00 86.01 ? 400 MET C CA 1 ATOM 2627 C C . MET A 1 335 ? -126.057 -138.792 178.149 1.00 90.34 ? 400 MET C C 1 ATOM 2628 O O . MET A 1 335 ? -126.850 -139.162 177.274 1.00 90.91 ? 400 MET C O 1 ATOM 2629 C CB . MET A 1 335 ? -127.101 -138.430 180.363 1.00 84.46 ? 400 MET C CB 1 ATOM 2630 C CG . MET A 1 335 ? -127.630 -137.457 181.370 1.00 87.29 ? 400 MET C CG 1 ATOM 2631 S SD . MET A 1 335 ? -128.467 -138.277 182.724 1.00 96.17 ? 400 MET C SD 1 ATOM 2632 C CE . MET A 1 335 ? -128.524 -136.932 183.900 1.00 81.76 ? 400 MET C CE 1 ATOM 2633 N N . PRO A 1 336 ? -124.814 -139.291 178.265 1.00 91.86 ? 401 PRO C N 1 ATOM 2634 C CA . PRO A 1 336 ? -124.448 -140.474 177.478 1.00 89.01 ? 401 PRO C CA 1 ATOM 2635 C C . PRO A 1 336 ? -125.304 -141.675 177.871 1.00 90.51 ? 401 PRO C C 1 ATOM 2636 O O . PRO A 1 336 ? -125.624 -141.842 179.055 1.00 88.52 ? 401 PRO C O 1 ATOM 2637 C CB . PRO A 1 336 ? -122.973 -140.697 177.822 1.00 77.47 ? 401 PRO C CB 1 ATOM 2638 C CG . PRO A 1 336 ? -122.709 -139.879 179.051 1.00 75.51 ? 401 PRO C CG 1 ATOM 2639 C CD . PRO A 1 336 ? -123.679 -138.750 179.032 1.00 90.00 ? 401 PRO C CD 1 ATOM 2640 N N . ALA A 1 337 ? -125.632 -142.519 176.899 1.00 92.95 ? 402 ALA C N 1 ATOM 2641 C CA . ALA A 1 337 ? -126.538 -143.643 177.119 1.00 92.06 ? 402 ALA C CA 1 ATOM 2642 C C . ALA A 1 337 ? -127.940 -143.175 177.463 1.00 90.87 ? 402 ALA C C 1 ATOM 2643 O O . ALA A 1 337 ? -128.676 -143.858 178.186 1.00 93.65 ? 402 ALA C O 1 ATOM 2644 C CB . ALA A 1 337 ? -126.008 -144.542 178.221 1.00 92.29 ? 402 ALA C CB 1 ATOM 2645 N N . SER A 1 338 ? -128.324 -142.032 176.905 1.00 89.60 ? 403 SER C N 1 ATOM 2646 C CA . SER A 1 338 ? -129.590 -141.400 177.254 1.00 87.10 ? 403 SER C CA 1 ATOM 2647 C C . SER A 1 338 ? -130.814 -142.278 176.965 1.00 86.81 ? 403 SER C C 1 ATOM 2648 O O . SER A 1 338 ? -131.773 -142.307 177.750 1.00 85.59 ? 403 SER C O 1 ATOM 2649 C CB . SER A 1 338 ? -129.711 -140.091 176.494 1.00 82.25 ? 403 SER C CB 1 ATOM 2650 O OG . SER A 1 338 ? -129.634 -140.354 175.109 1.00 84.22 ? 403 SER C OG 1 ATOM 2651 N N . THR A 1 339 ? -130.753 -143.037 175.877 1.00 81.09 ? 404 THR C N 1 ATOM 2652 C CA . THR A 1 339 ? -131.881 -143.852 175.466 1.00 79.08 ? 404 THR C CA 1 ATOM 2653 C C . THR A 1 339 ? -132.227 -144.860 176.547 1.00 83.30 ? 404 THR C C 1 ATOM 2654 O O . THR A 1 339 ? -133.393 -145.214 176.740 1.00 81.44 ? 404 THR C O 1 ATOM 2655 C CB . THR A 1 339 ? -131.574 -144.596 174.161 1.00 83.24 ? 404 THR C CB 1 ATOM 2656 O OG1 . THR A 1 339 ? -131.298 -143.639 173.131 1.00 90.15 ? 404 THR C OG1 1 ATOM 2657 C CG2 . THR A 1 339 ? -132.745 -145.481 173.748 1.00 75.00 ? 404 THR C CG2 1 ATOM 2658 N N . PHE A 1 340 ? -131.203 -145.313 177.263 1.00 82.26 ? 405 PHE C N 1 ATOM 2659 C CA . PHE A 1 340 ? -131.402 -146.297 178.317 1.00 78.63 ? 405 PHE C CA 1 ATOM 2660 C C . PHE A 1 340 ? -132.064 -145.673 179.542 1.00 81.12 ? 405 PHE C C 1 ATOM 2661 O O . PHE A 1 340 ? -133.023 -146.226 180.092 1.00 76.83 ? 405 PHE C O 1 ATOM 2662 C CB . PHE A 1 340 ? -130.068 -146.929 178.695 1.00 78.35 ? 405 PHE C CB 1 ATOM 2663 C CG . PHE A 1 340 ? -130.146 -147.840 179.871 1.00 72.94 ? 405 PHE C CG 1 ATOM 2664 C CD1 . PHE A 1 340 ? -130.778 -149.064 179.771 1.00 67.38 ? 405 PHE C CD1 1 ATOM 2665 C CD2 . PHE A 1 340 ? -129.573 -147.476 181.080 1.00 81.09 ? 405 PHE C CD2 1 ATOM 2666 C CE1 . PHE A 1 340 ? -130.855 -149.912 180.859 1.00 72.10 ? 405 PHE C CE1 1 ATOM 2667 C CE2 . PHE A 1 340 ? -129.643 -148.318 182.178 1.00 75.05 ? 405 PHE C CE2 1 ATOM 2668 C CZ . PHE A 1 340 ? -130.286 -149.538 182.065 1.00 72.74 ? 405 PHE C CZ 1 ATOM 2669 N N . TRP A 1 341 ? -131.575 -144.501 179.947 1.00 81.96 ? 406 TRP C N 1 ATOM 2670 C CA . TRP A 1 341 ? -132.154 -143.797 181.084 1.00 79.28 ? 406 TRP C CA 1 ATOM 2671 C C . TRP A 1 341 ? -133.607 -143.428 180.796 1.00 80.32 ? 406 TRP C C 1 ATOM 2672 O O . TRP A 1 341 ? -134.468 -143.483 181.678 1.00 72.29 ? 406 TRP C O 1 ATOM 2673 C CB . TRP A 1 341 ? -131.337 -142.545 181.399 1.00 77.63 ? 406 TRP C CB 1 ATOM 2674 C CG . TRP A 1 341 ? -129.895 -142.856 181.619 1.00 88.73 ? 406 TRP C CG 1 ATOM 2675 C CD1 . TRP A 1 341 ? -128.831 -142.412 180.894 1.00 88.03 ? 406 TRP C CD1 1 ATOM 2676 C CD2 . TRP A 1 341 ? -129.363 -143.729 182.623 1.00 93.82 ? 406 TRP C CD2 1 ATOM 2677 N NE1 . TRP A 1 341 ? -127.658 -142.944 181.404 1.00 93.01 ? 406 TRP C NE1 1 ATOM 2678 C CE2 . TRP A 1 341 ? -127.964 -143.756 182.465 1.00 88.78 ? 406 TRP C CE2 1 ATOM 2679 C CE3 . TRP A 1 341 ? -129.938 -144.480 183.652 1.00 91.20 ? 406 TRP C CE3 1 ATOM 2680 C CZ2 . TRP A 1 341 ? -127.138 -144.497 183.294 1.00 83.54 ? 406 TRP C CZ2 1 ATOM 2681 C CZ3 . TRP A 1 341 ? -129.112 -145.217 184.472 1.00 91.02 ? 406 TRP C CZ3 1 ATOM 2682 C CH2 . TRP A 1 341 ? -127.728 -145.219 184.289 1.00 87.31 ? 406 TRP C CH2 1 ATOM 2683 N N . ALA A 1 342 ? -133.898 -143.097 179.545 1.00 77.46 ? 407 ALA C N 1 ATOM 2684 C CA . ALA A 1 342 ? -135.246 -142.694 179.228 1.00 74.37 ? 407 ALA C CA 1 ATOM 2685 C C . ALA A 1 342 ? -136.196 -143.882 179.329 1.00 75.48 ? 407 ALA C C 1 ATOM 2686 O O . ALA A 1 342 ? -137.273 -143.763 179.913 1.00 76.51 ? 407 ALA C O 1 ATOM 2687 C CB . ALA A 1 342 ? -135.298 -142.074 177.853 1.00 77.39 ? 407 ALA C CB 1 ATOM 2688 N N . LEU A 1 343 ? -135.793 -145.033 178.787 1.00 80.31 ? 408 LEU C N 1 ATOM 2689 C CA . LEU A 1 343 ? -136.683 -146.207 178.737 1.00 78.78 ? 408 LEU C CA 1 ATOM 2690 C C . LEU A 1 343 ? -137.010 -146.760 180.123 1.00 76.61 ? 408 LEU C C 1 ATOM 2691 O O . LEU A 1 343 ? -138.140 -147.196 180.377 1.00 74.12 ? 408 LEU C O 1 ATOM 2692 C CB . LEU A 1 343 ? -136.069 -147.320 177.874 1.00 77.40 ? 408 LEU C CB 1 ATOM 2693 C CG . LEU A 1 343 ? -136.115 -147.137 176.352 1.00 81.19 ? 408 LEU C CG 1 ATOM 2694 C CD1 . LEU A 1 343 ? -135.121 -148.054 175.648 1.00 69.73 ? 408 LEU C CD1 1 ATOM 2695 C CD2 . LEU A 1 343 ? -137.526 -147.368 175.813 1.00 84.42 ? 408 LEU C CD2 1 ATOM 2696 N N . ILE A 1 344 ? -136.038 -146.726 181.032 1.00 73.17 ? 409 ILE C N 1 ATOM 2697 C CA . ILE A 1 344 ? -136.320 -147.201 182.376 1.00 75.36 ? 409 ILE C CA 1 ATOM 2698 C C . ILE A 1 344 ? -136.996 -146.124 183.218 1.00 73.68 ? 409 ILE C C 1 ATOM 2699 O O . ILE A 1 344 ? -137.738 -146.449 184.137 1.00 79.89 ? 409 ILE C O 1 ATOM 2700 C CB . ILE A 1 344 ? -135.053 -147.717 183.104 1.00 75.37 ? 409 ILE C CB 1 ATOM 2701 C CG1 . ILE A 1 344 ? -133.998 -146.624 183.246 1.00 75.42 ? 409 ILE C CG1 1 ATOM 2702 C CG2 . ILE A 1 344 ? -134.485 -148.924 182.381 1.00 66.56 ? 409 ILE C CG2 1 ATOM 2703 C CD1 . ILE A 1 344 ? -132.868 -147.019 184.167 1.00 71.45 ? 409 ILE C CD1 1 ATOM 2704 N N . PHE A 1 345 ? -136.772 -144.852 182.904 1.00 73.15 ? 410 PHE C N 1 ATOM 2705 C CA . PHE A 1 345 ? -137.468 -143.790 183.624 1.00 70.42 ? 410 PHE C CA 1 ATOM 2706 C C . PHE A 1 345 ? -138.960 -143.870 183.364 1.00 74.39 ? 410 PHE C C 1 ATOM 2707 O O . PHE A 1 345 ? -139.764 -143.907 184.298 1.00 73.86 ? 410 PHE C O 1 ATOM 2708 C CB . PHE A 1 345 ? -136.956 -142.415 183.216 1.00 71.82 ? 410 PHE C CB 1 ATOM 2709 C CG . PHE A 1 345 ? -137.659 -141.273 183.908 1.00 72.86 ? 410 PHE C CG 1 ATOM 2710 C CD1 . PHE A 1 345 ? -137.533 -141.094 185.280 1.00 73.11 ? 410 PHE C CD1 1 ATOM 2711 C CD2 . PHE A 1 345 ? -138.433 -140.371 183.190 1.00 73.19 ? 410 PHE C CD2 1 ATOM 2712 C CE1 . PHE A 1 345 ? -138.168 -140.042 185.919 1.00 66.45 ? 410 PHE C CE1 1 ATOM 2713 C CE2 . PHE A 1 345 ? -139.079 -139.320 183.828 1.00 69.47 ? 410 PHE C CE2 1 ATOM 2714 C CZ . PHE A 1 345 ? -138.941 -139.156 185.193 1.00 66.57 ? 410 PHE C CZ 1 ATOM 2715 N N . PHE A 1 346 ? -139.333 -143.921 182.090 1.00 72.62 ? 411 PHE C N 1 ATOM 2716 C CA . PHE A 1 346 ? -140.741 -143.934 181.754 1.00 69.40 ? 411 PHE C CA 1 ATOM 2717 C C . PHE A 1 346 ? -141.403 -145.253 182.122 1.00 75.66 ? 411 PHE C C 1 ATOM 2718 O O . PHE A 1 346 ? -142.602 -145.299 182.381 1.00 77.24 ? 411 PHE C O 1 ATOM 2719 C CB . PHE A 1 346 ? -140.924 -143.618 180.281 1.00 72.36 ? 411 PHE C CB 1 ATOM 2720 C CG . PHE A 1 346 ? -140.510 -142.222 179.929 1.00 72.60 ? 411 PHE C CG 1 ATOM 2721 C CD1 . PHE A 1 346 ? -141.104 -141.142 180.555 1.00 73.83 ? 411 PHE C CD1 1 ATOM 2722 C CD2 . PHE A 1 346 ? -139.522 -141.986 179.003 1.00 70.42 ? 411 PHE C CD2 1 ATOM 2723 C CE1 . PHE A 1 346 ? -140.717 -139.858 180.264 1.00 74.22 ? 411 PHE C CE1 1 ATOM 2724 C CE2 . PHE A 1 346 ? -139.137 -140.708 178.705 1.00 68.39 ? 411 PHE C CE2 1 ATOM 2725 C CZ . PHE A 1 346 ? -139.728 -139.642 179.341 1.00 72.25 ? 411 PHE C CZ 1 ATOM 2726 N N . MET A 1 347 ? -140.626 -146.329 182.155 1.00 80.27 ? 412 MET C N 1 ATOM 2727 C CA . MET A 1 347 ? -141.174 -147.596 182.600 1.00 78.11 ? 412 MET C CA 1 ATOM 2728 C C . MET A 1 347 ? -141.480 -147.502 184.096 1.00 77.87 ? 412 MET C C 1 ATOM 2729 O O . MET A 1 347 ? -142.539 -147.948 184.562 1.00 74.55 ? 412 MET C O 1 ATOM 2730 C CB . MET A 1 347 ? -140.202 -148.732 182.314 1.00 81.90 ? 412 MET C CB 1 ATOM 2731 C CG . MET A 1 347 ? -140.803 -150.126 182.491 1.00 88.81 ? 412 MET C CG 1 ATOM 2732 S SD . MET A 1 347 ? -142.438 -150.247 181.731 1.00 103.44 ? 412 MET C SD 1 ATOM 2733 C CE . MET A 1 347 ? -142.682 -152.022 181.781 1.00 104.12 ? 412 MET C CE 1 ATOM 2734 N N . MET A 1 348 ? -140.562 -146.883 184.839 1.00 77.34 ? 413 MET C N 1 ATOM 2735 C CA . MET A 1 348 ? -140.738 -146.718 186.270 1.00 71.37 ? 413 MET C CA 1 ATOM 2736 C C . MET A 1 348 ? -141.962 -145.864 186.528 1.00 74.27 ? 413 MET C C 1 ATOM 2737 O O . MET A 1 348 ? -142.721 -146.127 187.464 1.00 72.79 ? 413 MET C O 1 ATOM 2738 C CB . MET A 1 348 ? -139.508 -146.063 186.917 1.00 68.89 ? 413 MET C CB 1 ATOM 2739 C CG . MET A 1 348 ? -139.766 -145.616 188.364 1.00 77.29 ? 413 MET C CG 1 ATOM 2740 S SD . MET A 1 348 ? -138.539 -144.525 189.131 1.00 80.50 ? 413 MET C SD 1 ATOM 2741 C CE . MET A 1 348 ? -138.663 -143.071 188.105 1.00 76.47 ? 413 MET C CE 1 ATOM 2742 N N . LEU A 1 349 ? -142.168 -144.848 185.691 1.00 74.73 ? 414 LEU C N 1 ATOM 2743 C CA . LEU A 1 349 ? -143.290 -143.948 185.913 1.00 73.33 ? 414 LEU C CA 1 ATOM 2744 C C . LEU A 1 349 ? -144.595 -144.712 185.799 1.00 71.88 ? 414 LEU C C 1 ATOM 2745 O O . LEU A 1 349 ? -145.507 -144.525 186.596 1.00 69.45 ? 414 LEU C O 1 ATOM 2746 C CB . LEU A 1 349 ? -143.267 -142.789 184.920 1.00 72.42 ? 414 LEU C CB 1 ATOM 2747 C CG . LEU A 1 349 ? -142.207 -141.707 185.152 1.00 70.33 ? 414 LEU C CG 1 ATOM 2748 C CD1 . LEU A 1 349 ? -142.423 -140.506 184.210 1.00 68.29 ? 414 LEU C CD1 1 ATOM 2749 C CD2 . LEU A 1 349 ? -142.215 -141.260 186.590 1.00 62.31 ? 414 LEU C CD2 1 ATOM 2750 N N . ALA A 1 350 ? -144.648 -145.626 184.839 1.00 73.25 ? 415 ALA C N 1 ATOM 2751 C CA . ALA A 1 350 ? -145.869 -146.362 184.572 1.00 71.12 ? 415 ALA C CA 1 ATOM 2752 C C . ALA A 1 350 ? -146.140 -147.383 185.670 1.00 76.31 ? 415 ALA C C 1 ATOM 2753 O O . ALA A 1 350 ? -147.277 -147.528 186.126 1.00 77.41 ? 415 ALA C O 1 ATOM 2754 C CB . ALA A 1 350 ? -145.792 -147.046 183.219 1.00 69.61 ? 415 ALA C CB 1 ATOM 2755 N N . THR A 1 351 ? -145.109 -148.114 186.082 1.00 78.05 ? 416 THR C N 1 ATOM 2756 C CA . THR A 1 351 ? -145.285 -149.094 187.148 1.00 73.33 ? 416 THR C CA 1 ATOM 2757 C C . THR A 1 351 ? -145.585 -148.388 188.471 1.00 74.99 ? 416 THR C C 1 ATOM 2758 O O . THR A 1 351 ? -146.215 -148.958 189.353 1.00 75.53 ? 416 THR C O 1 ATOM 2759 C CB . THR A 1 351 ? -144.049 -150.003 187.295 1.00 69.06 ? 416 THR C CB 1 ATOM 2760 O OG1 . THR A 1 351 ? -142.877 -149.196 187.457 1.00 69.52 ? 416 THR C OG1 1 ATOM 2761 C CG2 . THR A 1 351 ? -143.900 -150.860 186.062 1.00 68.24 ? 416 THR C CG2 1 ATOM 2762 N N . LEU A 1 352 ? -145.114 -147.151 188.611 1.00 71.16 ? 417 LEU C N 1 ATOM 2763 C CA . LEU A 1 352 ? -145.427 -146.360 189.795 1.00 66.65 ? 417 LEU C CA 1 ATOM 2764 C C . LEU A 1 352 ? -146.908 -146.059 189.875 1.00 70.35 ? 417 LEU C C 1 ATOM 2765 O O . LEU A 1 352 ? -147.466 -145.960 190.963 1.00 74.30 ? 417 LEU C O 1 ATOM 2766 C CB . LEU A 1 352 ? -144.634 -145.058 189.802 1.00 72.29 ? 417 LEU C CB 1 ATOM 2767 C CG . LEU A 1 352 ? -143.311 -145.131 190.555 1.00 70.71 ? 417 LEU C CG 1 ATOM 2768 C CD1 . LEU A 1 352 ? -142.519 -143.854 190.363 1.00 64.84 ? 417 LEU C CD1 1 ATOM 2769 C CD2 . LEU A 1 352 ? -143.592 -145.402 192.024 1.00 67.48 ? 417 LEU C CD2 1 ATOM 2770 N N . GLY A 1 353 ? -147.542 -145.912 188.713 1.00 75.07 ? 418 GLY C N 1 ATOM 2771 C CA . GLY A 1 353 ? -148.954 -145.587 188.648 1.00 71.89 ? 418 GLY C CA 1 ATOM 2772 C C . GLY A 1 353 ? -149.877 -146.786 188.631 1.00 74.24 ? 418 GLY C C 1 ATOM 2773 O O . GLY A 1 353 ? -150.992 -146.724 189.164 1.00 77.75 ? 418 GLY C O 1 ATOM 2774 N N . LEU A 1 354 ? -149.400 -147.887 188.050 1.00 75.10 ? 419 LEU C N 1 ATOM 2775 C CA . LEU A 1 354 ? -150.205 -149.097 187.894 1.00 73.49 ? 419 LEU C CA 1 ATOM 2776 C C . LEU A 1 354 ? -150.670 -149.716 189.211 1.00 76.63 ? 419 LEU C C 1 ATOM 2777 O O . LEU A 1 354 ? -151.854 -150.036 189.325 1.00 75.53 ? 419 LEU C O 1 ATOM 2778 C CB . LEU A 1 354 ? -149.436 -150.148 187.099 1.00 74.79 ? 419 LEU C CB 1 ATOM 2779 C CG . LEU A 1 354 ? -149.422 -149.982 185.572 1.00 73.66 ? 419 LEU C CG 1 ATOM 2780 C CD1 . LEU A 1 354 ? -148.379 -150.882 184.950 1.00 66.92 ? 419 LEU C CD1 1 ATOM 2781 C CD2 . LEU A 1 354 ? -150.779 -150.291 184.991 1.00 70.02 ? 419 LEU C CD2 1 ATOM 2782 N N . ASP A 1 355 ? -149.782 -149.851 190.209 1.00 80.76 ? 420 ASP C N 1 ATOM 2783 C CA . ASP A 1 355 ? -150.182 -150.479 191.477 1.00 70.71 ? 420 ASP C CA 1 ATOM 2784 C C . ASP A 1 355 ? -151.296 -149.649 192.066 1.00 76.62 ? 420 ASP C C 1 ATOM 2785 O O . ASP A 1 355 ? -152.191 -150.179 192.731 1.00 80.09 ? 420 ASP C O 1 ATOM 2786 C CB . ASP A 1 355 ? -149.077 -150.540 192.539 1.00 75.12 ? 420 ASP C CB 1 ATOM 2787 C CG . ASP A 1 355 ? -147.684 -150.780 191.985 1.00 80.54 ? 420 ASP C CG 1 ATOM 2788 O OD1 . ASP A 1 355 ? -147.240 -151.961 191.959 1.00 79.26 ? 420 ASP C OD1 1 ATOM 2789 O OD2 . ASP A 1 355 ? -147.003 -149.774 191.672 1.00 74.97 ? 420 ASP C OD2 1 ATOM 2790 N N . SER A 1 356 ? -151.227 -148.339 191.831 1.00 76.10 ? 421 SER C N 1 ATOM 2791 C CA . SER A 1 356 ? -152.149 -147.410 192.457 1.00 73.36 ? 421 SER C CA 1 ATOM 2792 C C . SER A 1 356 ? -153.514 -147.477 191.792 1.00 78.84 ? 421 SER C C 1 ATOM 2793 O O . SER A 1 356 ? -154.542 -147.493 192.477 1.00 79.20 ? 421 SER C O 1 ATOM 2794 C CB . SER A 1 356 ? -151.592 -145.991 192.411 1.00 74.65 ? 421 SER C CB 1 ATOM 2795 O OG . SER A 1 356 ? -150.434 -145.861 193.226 1.00 73.19 ? 421 SER C OG 1 ATOM 2796 N N . SER A 1 357 ? -153.540 -147.548 190.465 1.00 80.21 ? 422 SER C N 1 ATOM 2797 C CA . SER A 1 357 ? -154.820 -147.722 189.804 1.00 81.80 ? 422 SER C CA 1 ATOM 2798 C C . SER A 1 357 ? -155.417 -149.081 190.175 1.00 80.11 ? 422 SER C C 1 ATOM 2799 O O . SER A 1 357 ? -156.640 -149.212 190.255 1.00 83.62 ? 422 SER C O 1 ATOM 2800 C CB . SER A 1 357 ? -154.690 -147.601 188.284 1.00 86.06 ? 422 SER C CB 1 ATOM 2801 O OG . SER A 1 357 ? -155.982 -147.694 187.684 1.00 92.81 ? 422 SER C OG 1 ATOM 2802 N N . PHE A 1 358 ? -154.558 -150.076 190.420 1.00 77.18 ? 423 PHE C N 1 ATOM 2803 C CA . PHE A 1 358 ? -155.019 -151.399 190.838 1.00 74.10 ? 423 PHE C CA 1 ATOM 2804 C C . PHE A 1 358 ? -155.855 -151.269 192.092 1.00 78.96 ? 423 PHE C C 1 ATOM 2805 O O . PHE A 1 358 ? -156.965 -151.793 192.182 1.00 83.43 ? 423 PHE C O 1 ATOM 2806 C CB . PHE A 1 358 ? -153.855 -152.345 191.141 1.00 74.20 ? 423 PHE C CB 1 ATOM 2807 C CG . PHE A 1 358 ? -153.117 -152.838 189.927 1.00 74.37 ? 423 PHE C CG 1 ATOM 2808 C CD1 . PHE A 1 358 ? -153.554 -152.528 188.652 1.00 75.21 ? 423 PHE C CD1 1 ATOM 2809 C CD2 . PHE A 1 358 ? -151.978 -153.619 190.072 1.00 69.89 ? 423 PHE C CD2 1 ATOM 2810 C CE1 . PHE A 1 358 ? -152.865 -152.983 187.544 1.00 72.91 ? 423 PHE C CE1 1 ATOM 2811 C CE2 . PHE A 1 358 ? -151.286 -154.085 188.970 1.00 69.29 ? 423 PHE C CE2 1 ATOM 2812 C CZ . PHE A 1 358 ? -151.728 -153.770 187.704 1.00 69.82 ? 423 PHE C CZ 1 ATOM 2813 N N . GLY A 1 359 ? -155.315 -150.544 193.063 1.00 77.36 ? 424 GLY C N 1 ATOM 2814 C CA . GLY A 1 359 ? -155.951 -150.443 194.358 1.00 75.76 ? 424 GLY C CA 1 ATOM 2815 C C . GLY A 1 359 ? -157.247 -149.672 194.279 1.00 77.75 ? 424 GLY C C 1 ATOM 2816 O O . GLY A 1 359 ? -158.208 -150.004 194.959 1.00 81.60 ? 424 GLY C O 1 ATOM 2817 N N . GLY A 1 360 ? -157.291 -148.650 193.434 1.00 77.84 ? 425 GLY C N 1 ATOM 2818 C CA . GLY A 1 360 ? -158.500 -147.867 193.316 1.00 73.87 ? 425 GLY C CA 1 ATOM 2819 C C . GLY A 1 360 ? -159.610 -148.727 192.755 1.00 77.40 ? 425 GLY C C 1 ATOM 2820 O O . GLY A 1 360 ? -160.719 -148.736 193.279 1.00 80.11 ? 425 GLY C O 1 ATOM 2821 N N . SER A 1 361 ? -159.304 -149.489 191.715 1.00 75.85 ? 426 SER C N 1 ATOM 2822 C CA . SER A 1 361 ? -160.297 -150.356 191.109 1.00 78.76 ? 426 SER C CA 1 ATOM 2823 C C . SER A 1 361 ? -160.720 -151.470 192.076 1.00 82.74 ? 426 SER C C 1 ATOM 2824 O O . SER A 1 361 ? -161.913 -151.808 192.180 1.00 82.62 ? 426 SER C O 1 ATOM 2825 C CB . SER A 1 361 ? -159.745 -150.944 189.807 1.00 80.60 ? 426 SER C CB 1 ATOM 2826 O OG . SER A 1 361 ? -159.253 -149.920 188.952 1.00 83.89 ? 426 SER C OG 1 ATOM 2827 N N . GLU A 1 362 ? -159.755 -152.023 192.806 1.00 80.43 ? 427 GLU C N 1 ATOM 2828 C CA . GLU A 1 362 ? -160.060 -153.114 193.711 1.00 78.35 ? 427 GLU C CA 1 ATOM 2829 C C . GLU A 1 362 ? -160.938 -152.630 194.845 1.00 78.71 ? 427 GLU C C 1 ATOM 2830 O O . GLU A 1 362 ? -161.742 -153.389 195.372 1.00 85.94 ? 427 GLU C O 1 ATOM 2831 C CB . GLU A 1 362 ? -158.791 -153.742 194.270 1.00 81.79 ? 427 GLU C CB 1 ATOM 2832 C CG . GLU A 1 362 ? -159.078 -154.967 195.128 1.00 83.39 ? 427 GLU C CG 1 ATOM 2833 C CD . GLU A 1 362 ? -159.818 -156.050 194.356 1.00 92.88 ? 427 GLU C CD 1 ATOM 2834 O OE1 . GLU A 1 362 ? -159.491 -156.258 193.168 1.00 95.56 ? 427 GLU C OE1 1 ATOM 2835 O OE2 . GLU A 1 362 ? -160.731 -156.690 194.930 1.00 94.14 ? 427 GLU C OE2 1 ATOM 2836 N N . ALA A 1 363 ? -160.802 -151.363 195.210 1.00 74.22 ? 428 ALA C N 1 ATOM 2837 C CA . ALA A 1 363 ? -161.664 -150.812 196.239 1.00 76.78 ? 428 ALA C CA 1 ATOM 2838 C C . ALA A 1 363 ? -163.083 -150.885 195.741 1.00 80.26 ? 428 ALA C C 1 ATOM 2839 O O . ALA A 1 363 ? -164.011 -151.112 196.510 1.00 84.68 ? 428 ALA C O 1 ATOM 2840 C CB . ALA A 1 363 ? -161.291 -149.368 196.568 1.00 77.23 ? 428 ALA C CB 1 ATOM 2841 N N . ILE A 1 364 ? -163.232 -150.709 194.433 1.00 83.19 ? 429 ILE C N 1 ATOM 2842 C CA . ILE A 1 364 ? -164.539 -150.690 193.805 1.00 84.55 ? 429 ILE C CA 1 ATOM 2843 C C . ILE A 1 364 ? -165.075 -152.100 193.631 1.00 88.16 ? 429 ILE C C 1 ATOM 2844 O O . ILE A 1 364 ? -166.182 -152.410 194.087 1.00 85.13 ? 429 ILE C O 1 ATOM 2845 C CB . ILE A 1 364 ? -164.493 -149.992 192.429 1.00 83.46 ? 429 ILE C CB 1 ATOM 2846 C CG1 . ILE A 1 364 ? -164.226 -148.497 192.605 1.00 79.06 ? 429 ILE C CG1 1 ATOM 2847 C CG2 . ILE A 1 364 ? -165.797 -150.201 191.678 1.00 84.31 ? 429 ILE C CG2 1 ATOM 2848 C CD1 . ILE A 1 364 ? -164.101 -147.740 191.297 1.00 84.13 ? 429 ILE C CD1 1 ATOM 2849 N N . ILE A 1 365 ? -164.285 -152.963 192.995 1.00 85.29 ? 430 ILE C N 1 ATOM 2850 C CA . ILE A 1 365 ? -164.749 -154.315 192.719 1.00 82.92 ? 430 ILE C CA 1 ATOM 2851 C C . ILE A 1 365 ? -165.102 -155.027 194.010 1.00 85.49 ? 430 ILE C C 1 ATOM 2852 O O . ILE A 1 365 ? -166.181 -155.596 194.135 1.00 89.23 ? 430 ILE C O 1 ATOM 2853 C CB . ILE A 1 365 ? -163.697 -155.139 191.986 1.00 89.81 ? 430 ILE C CB 1 ATOM 2854 C CG1 . ILE A 1 365 ? -163.220 -154.420 190.723 1.00 87.83 ? 430 ILE C CG1 1 ATOM 2855 C CG2 . ILE A 1 365 ? -164.245 -156.508 191.671 1.00 87.81 ? 430 ILE C CG2 1 ATOM 2856 C CD1 . ILE A 1 365 ? -162.064 -155.117 190.059 1.00 83.57 ? 430 ILE C CD1 1 ATOM 2857 N N . THR A 1 366 ? -164.197 -154.962 194.985 1.00 84.65 ? 431 THR C N 1 ATOM 2858 C CA . THR A 1 366 ? -164.421 -155.627 196.258 1.00 79.07 ? 431 THR C CA 1 ATOM 2859 C C . THR A 1 366 ? -165.630 -155.052 196.965 1.00 83.07 ? 431 THR C C 1 ATOM 2860 O O . THR A 1 366 ? -166.387 -155.784 197.586 1.00 88.93 ? 431 THR C O 1 ATOM 2861 C CB . THR A 1 366 ? -163.208 -155.503 197.188 1.00 77.62 ? 431 THR C CB 1 ATOM 2862 O OG1 . THR A 1 366 ? -162.194 -156.422 196.776 1.00 81.36 ? 431 THR C OG1 1 ATOM 2863 C CG2 . THR A 1 366 ? -163.596 -155.819 198.614 1.00 75.24 ? 431 THR C CG2 1 ATOM 2864 N N . ALA A 1 367 ? -165.848 -153.751 196.850 1.00 82.35 ? 432 ALA C N 1 ATOM 2865 C CA . ALA A 1 367 ? -167.001 -153.173 197.517 1.00 83.36 ? 432 ALA C CA 1 ATOM 2866 C C . ALA A 1 367 ? -168.270 -153.714 196.874 1.00 86.45 ? 432 ALA C C 1 ATOM 2867 O O . ALA A 1 367 ? -169.153 -154.233 197.553 1.00 84.25 ? 432 ALA C O 1 ATOM 2868 C CB . ALA A 1 367 ? -166.961 -151.657 197.456 1.00 77.87 ? 432 ALA C CB 1 ATOM 2869 N N . LEU A 1 368 ? -168.339 -153.624 195.552 1.00 87.17 ? 433 LEU C N 1 ATOM 2870 C CA . LEU A 1 368 ? -169.507 -154.107 194.831 1.00 89.47 ? 433 LEU C CA 1 ATOM 2871 C C . LEU A 1 368 ? -169.630 -155.630 194.878 1.00 89.99 ? 433 LEU C C 1 ATOM 2872 O O . LEU A 1 368 ? -170.738 -156.160 194.869 1.00 93.65 ? 433 LEU C O 1 ATOM 2873 C CB . LEU A 1 368 ? -169.474 -153.619 193.383 1.00 88.67 ? 433 LEU C CB 1 ATOM 2874 C CG . LEU A 1 368 ? -169.474 -152.097 193.255 1.00 85.69 ? 433 LEU C CG 1 ATOM 2875 C CD1 . LEU A 1 368 ? -169.461 -151.675 191.798 1.00 92.90 ? 433 LEU C CD1 1 ATOM 2876 C CD2 . LEU A 1 368 ? -170.648 -151.486 193.994 1.00 76.16 ? 433 LEU C CD2 1 ATOM 2877 N N . SER A 1 369 ? -168.503 -156.335 194.952 1.00 88.68 ? 434 SER C N 1 ATOM 2878 C CA . SER A 1 369 ? -168.543 -157.799 195.005 1.00 89.53 ? 434 SER C CA 1 ATOM 2879 C C . SER A 1 369 ? -169.208 -158.287 196.290 1.00 92.97 ? 434 SER C C 1 ATOM 2880 O O . SER A 1 369 ? -169.774 -159.377 196.324 1.00 101.11 ? 434 SER C O 1 ATOM 2881 C CB . SER A 1 369 ? -167.137 -158.396 194.893 1.00 85.71 ? 434 SER C CB 1 ATOM 2882 O OG . SER A 1 369 ? -166.722 -158.474 193.542 1.00 84.04 ? 434 SER C OG 1 ATOM 2883 N N . ASP A 1 370 ? -169.141 -157.478 197.341 1.00 87.41 ? 435 ASP C N 1 ATOM 2884 C CA . ASP A 1 370 ? -169.668 -157.875 198.635 1.00 87.44 ? 435 ASP C CA 1 ATOM 2885 C C . ASP A 1 370 ? -171.118 -157.440 198.833 1.00 92.75 ? 435 ASP C C 1 ATOM 2886 O O . ASP A 1 370 ? -171.880 -158.115 199.529 1.00 99.02 ? 435 ASP C O 1 ATOM 2887 C CB . ASP A 1 370 ? -168.782 -157.324 199.763 1.00 90.24 ? 435 ASP C CB 1 ATOM 2888 C CG . ASP A 1 370 ? -167.403 -158.001 199.820 1.00 92.32 ? 435 ASP C CG 1 ATOM 2889 O OD1 . ASP A 1 370 ? -167.175 -158.997 199.091 1.00 91.26 ? 435 ASP C OD1 1 ATOM 2890 O OD2 . ASP A 1 370 ? -166.547 -157.544 200.611 1.00 93.22 ? 435 ASP C OD2 1 ATOM 2891 N N . GLU A 1 371 ? -171.492 -156.300 198.254 1.00 94.44 ? 436 GLU C N 1 ATOM 2892 C CA . GLU A 1 371 ? -172.898 -155.868 198.252 1.00 95.18 ? 436 GLU C CA 1 ATOM 2893 C C . GLU A 1 371 ? -173.781 -156.704 197.322 1.00 97.11 ? 436 GLU C C 1 ATOM 2894 O O . GLU A 1 371 ? -174.976 -156.875 197.562 1.00 96.05 ? 436 GLU C O 1 ATOM 2895 C CB . GLU A 1 371 ? -173.020 -154.401 197.848 1.00 88.06 ? 436 GLU C CB 1 ATOM 2896 C CG . GLU A 1 371 ? -172.719 -153.438 198.960 1.00 95.63 ? 436 GLU C CG 1 ATOM 2897 C CD . GLU A 1 371 ? -173.557 -153.712 200.187 1.00 101.11 ? 436 GLU C CD 1 ATOM 2898 O OE1 . GLU A 1 371 ? -174.750 -153.343 200.184 1.00 98.52 ? 436 GLU C OE1 1 ATOM 2899 O OE2 . GLU A 1 371 ? -173.026 -154.300 201.154 1.00 103.79 ? 436 GLU C OE2 1 ATOM 2900 N N . PHE A 1 372 ? -173.191 -157.214 196.249 1.00 89.63 ? 437 PHE C N 1 ATOM 2901 C CA . PHE A 1 372 ? -173.981 -157.804 195.194 1.00 91.24 ? 437 PHE C CA 1 ATOM 2902 C C . PHE A 1 372 ? -173.375 -159.116 194.718 1.00 99.13 ? 437 PHE C C 1 ATOM 2903 O O . PHE A 1 372 ? -172.440 -159.123 193.917 1.00 101.53 ? 437 PHE C O 1 ATOM 2904 C CB . PHE A 1 372 ? -174.128 -156.801 194.043 1.00 96.48 ? 437 PHE C CB 1 ATOM 2905 C CG . PHE A 1 372 ? -174.796 -155.507 194.452 1.00 92.53 ? 437 PHE C CG 1 ATOM 2906 C CD1 . PHE A 1 372 ? -176.166 -155.456 194.651 1.00 93.31 ? 437 PHE C CD1 1 ATOM 2907 C CD2 . PHE A 1 372 ? -174.056 -154.349 194.650 1.00 92.45 ? 437 PHE C CD2 1 ATOM 2908 C CE1 . PHE A 1 372 ? -176.788 -154.274 195.036 1.00 92.58 ? 437 PHE C CE1 1 ATOM 2909 C CE2 . PHE A 1 372 ? -174.675 -153.163 195.039 1.00 88.28 ? 437 PHE C CE2 1 ATOM 2910 C CZ . PHE A 1 372 ? -176.040 -153.131 195.231 1.00 87.65 ? 437 PHE C CZ 1 ATOM 2911 N N . PRO A 1 373 ? -173.937 -160.236 195.188 1.00 100.65 ? 438 PRO C N 1 ATOM 2912 C CA . PRO A 1 373 ? -173.460 -161.571 194.829 1.00 98.86 ? 438 PRO C CA 1 ATOM 2913 C C . PRO A 1 373 ? -173.559 -161.746 193.330 1.00 98.37 ? 438 PRO C C 1 ATOM 2914 O O . PRO A 1 373 ? -172.791 -162.513 192.740 1.00 99.49 ? 438 PRO C O 1 ATOM 2915 C CB . PRO A 1 373 ? -174.418 -162.507 195.574 1.00 94.12 ? 438 PRO C CB 1 ATOM 2916 C CG . PRO A 1 373 ? -175.576 -161.653 195.970 1.00 97.50 ? 438 PRO C CG 1 ATOM 2917 C CD . PRO A 1 373 ? -175.024 -160.286 196.176 1.00 95.88 ? 438 PRO C CD 1 ATOM 2918 N N . LYS A 1 374 ? -174.513 -161.043 192.729 1.00 98.93 ? 439 LYS C N 1 ATOM 2919 C CA . LYS A 1 374 ? -174.672 -161.053 191.280 1.00 103.90 ? 439 LYS C CA 1 ATOM 2920 C C . LYS A 1 374 ? -173.343 -160.754 190.564 1.00 107.67 ? 439 LYS C C 1 ATOM 2921 O O . LYS A 1 374 ? -172.904 -161.545 189.720 1.00 105.20 ? 439 LYS C O 1 ATOM 2922 C CB . LYS A 1 374 ? -175.750 -160.041 190.863 1.00 95.09 ? 439 LYS C CB 1 ATOM 2923 N N . ILE A 1 375 ? -172.688 -159.644 190.927 1.00 101.19 ? 440 ILE C N 1 ATOM 2924 C CA . ILE A 1 375 ? -171.435 -159.257 190.267 1.00 102.68 ? 440 ILE C CA 1 ATOM 2925 C C . ILE A 1 375 ? -170.221 -160.037 190.790 1.00 99.92 ? 440 ILE C C 1 ATOM 2926 O O . ILE A 1 375 ? -169.250 -160.267 190.057 1.00 97.79 ? 440 ILE C O 1 ATOM 2927 C CB . ILE A 1 375 ? -171.151 -157.727 190.389 1.00 100.08 ? 440 ILE C CB 1 ATOM 2928 C CG1 . ILE A 1 375 ? -170.853 -157.337 191.818 1.00 96.44 ? 440 ILE C CG1 1 ATOM 2929 C CG2 . ILE A 1 375 ? -172.292 -156.883 189.832 1.00 103.04 ? 440 ILE C CG2 1 ATOM 2930 C CD1 . ILE A 1 375 ? -169.411 -157.002 192.017 1.00 97.75 ? 440 ILE C CD1 1 ATOM 2931 N N . LYS A 1 376 ? -170.285 -160.459 192.048 1.00 96.19 ? 441 LYS C N 1 ATOM 2932 C CA . LYS A 1 376 ? -169.223 -161.277 192.626 1.00 96.98 ? 441 LYS C CA 1 ATOM 2933 C C . LYS A 1 376 ? -169.081 -162.622 191.922 1.00 102.24 ? 441 LYS C C 1 ATOM 2934 O O . LYS A 1 376 ? -167.971 -163.147 191.771 1.00 97.86 ? 441 LYS C O 1 ATOM 2935 C CB . LYS A 1 376 ? -169.486 -161.513 194.109 1.00 98.14 ? 441 LYS C CB 1 ATOM 2936 C CG . LYS A 1 376 ? -168.509 -162.473 194.762 1.00 95.71 ? 441 LYS C CG 1 ATOM 2937 C CD . LYS A 1 376 ? -168.736 -162.521 196.256 1.00 92.66 ? 441 LYS C CD 1 ATOM 2938 C CE . LYS A 1 376 ? -167.643 -163.306 196.945 1.00 101.35 ? 441 LYS C CE 1 ATOM 2939 N NZ . LYS A 1 376 ? -167.798 -163.223 198.425 1.00 108.92 ? 441 LYS C NZ 1 ATOM 2940 N N . ARG A 1 377 ? -170.215 -163.171 191.489 1.00 107.60 ? 442 ARG C N 1 ATOM 2941 C CA . ARG A 1 377 ? -170.236 -164.426 190.749 1.00 107.14 ? 442 ARG C CA 1 ATOM 2942 C C . ARG A 1 377 ? -169.660 -164.216 189.360 1.00 107.60 ? 442 ARG C C 1 ATOM 2943 O O . ARG A 1 377 ? -169.128 -165.142 188.749 1.00 110.71 ? 442 ARG C O 1 ATOM 2944 C CB . ARG A 1 377 ? -171.663 -164.976 190.665 1.00 106.61 ? 442 ARG C CB 1 ATOM 2945 N N . ASN A 1 378 ? -169.748 -162.976 188.884 1.00 107.71 ? 443 ASN C N 1 ATOM 2946 C CA . ASN A 1 378 ? -169.370 -162.645 187.516 1.00 111.39 ? 443 ASN C CA 1 ATOM 2947 C C . ASN A 1 378 ? -168.249 -161.618 187.403 1.00 105.93 ? 443 ASN C C 1 ATOM 2948 O O . ASN A 1 378 ? -168.292 -160.738 186.544 1.00 107.03 ? 443 ASN C O 1 ATOM 2949 C CB . ASN A 1 378 ? -170.595 -162.144 186.754 1.00 112.15 ? 443 ASN C CB 1 ATOM 2950 C CG . ASN A 1 378 ? -171.569 -163.253 186.445 1.00 111.02 ? 443 ASN C CG 1 ATOM 2951 O OD1 . ASN A 1 378 ? -171.225 -164.222 185.764 1.00 104.72 ? 443 ASN C OD1 1 ATOM 2952 N ND2 . ASN A 1 378 ? -172.795 -163.119 186.943 1.00 111.33 ? 443 ASN C ND2 1 ATOM 2953 N N . ARG A 1 379 ? -167.231 -161.760 188.245 1.00 102.57 ? 444 ARG C N 1 ATOM 2954 C CA . ARG A 1 379 ? -166.159 -160.775 188.321 1.00 99.13 ? 444 ARG C CA 1 ATOM 2955 C C . ARG A 1 379 ? -165.495 -160.478 186.977 1.00 98.21 ? 444 ARG C C 1 ATOM 2956 O O . ARG A 1 379 ? -165.376 -159.317 186.586 1.00 97.63 ? 444 ARG C O 1 ATOM 2957 C CB . ARG A 1 379 ? -165.095 -161.241 189.310 1.00 96.17 ? 444 ARG C CB 1 ATOM 2958 C CG . ARG A 1 379 ? -163.803 -160.460 189.223 1.00 93.62 ? 444 ARG C CG 1 ATOM 2959 C CD . ARG A 1 379 ? -163.107 -160.403 190.565 1.00 94.75 ? 444 ARG C CD 1 ATOM 2960 N NE . ARG A 1 379 ? -162.128 -159.324 190.631 1.00 99.28 ? 444 ARG C NE 1 ATOM 2961 C CZ . ARG A 1 379 ? -161.479 -158.974 191.734 1.00 96.11 ? 444 ARG C CZ 1 ATOM 2962 N NH1 . ARG A 1 379 ? -161.712 -159.625 192.863 1.00 100.46 ? 444 ARG C NH1 1 ATOM 2963 N NH2 . ARG A 1 379 ? -160.607 -157.975 191.710 1.00 87.92 ? 444 ARG C NH2 1 ATOM 2964 N N . GLU A 1 380 ? -165.114 -161.523 186.252 1.00 103.63 ? 445 GLU C N 1 ATOM 2965 C CA . GLU A 1 380 ? -164.352 -161.345 185.019 1.00 101.66 ? 445 GLU C CA 1 ATOM 2966 C C . GLU A 1 380 ? -165.195 -160.542 184.034 1.00 100.16 ? 445 GLU C C 1 ATOM 2967 O O . GLU A 1 380 ? -164.683 -159.770 183.220 1.00 93.38 ? 445 GLU C O 1 ATOM 2968 C CB . GLU A 1 380 ? -163.949 -162.701 184.445 1.00 94.78 ? 445 GLU C CB 1 ATOM 2969 C CG . GLU A 1 380 ? -163.522 -163.682 185.536 1.00 103.20 ? 445 GLU C CG 1 ATOM 2970 C CD . GLU A 1 380 ? -163.130 -165.044 185.002 1.00 117.18 ? 445 GLU C CD 1 ATOM 2971 O OE1 . GLU A 1 380 ? -163.843 -165.558 184.113 1.00 130.02 ? 445 GLU C OE1 1 ATOM 2972 O OE2 . GLU A 1 380 ? -162.107 -165.603 185.464 1.00 115.80 ? 445 GLU C OE2 1 ATOM 2973 N N . LEU A 1 381 ? -166.507 -160.693 184.153 1.00 102.47 ? 446 LEU C N 1 ATOM 2974 C CA . LEU A 1 381 ? -167.421 -159.912 183.338 1.00 98.47 ? 446 LEU C CA 1 ATOM 2975 C C . LEU A 1 381 ? -167.516 -158.471 183.824 1.00 93.82 ? 446 LEU C C 1 ATOM 2976 O O . LEU A 1 381 ? -167.457 -157.546 183.023 1.00 92.99 ? 446 LEU C O 1 ATOM 2977 C CB . LEU A 1 381 ? -168.806 -160.561 183.333 1.00 104.05 ? 446 LEU C CB 1 ATOM 2978 C CG . LEU A 1 381 ? -169.855 -159.945 182.409 1.00 100.69 ? 446 LEU C CG 1 ATOM 2979 C CD1 . LEU A 1 381 ? -169.602 -160.359 180.956 1.00 95.94 ? 446 LEU C CD1 1 ATOM 2980 C CD2 . LEU A 1 381 ? -171.274 -160.297 182.876 1.00 99.80 ? 446 LEU C CD2 1 ATOM 2981 N N . PHE A 1 382 ? -167.646 -158.278 185.134 1.00 92.53 ? 447 PHE C N 1 ATOM 2982 C CA . PHE A 1 382 ? -167.928 -156.948 185.666 1.00 91.04 ? 447 PHE C CA 1 ATOM 2983 C C . PHE A 1 382 ? -166.806 -155.953 185.404 1.00 92.82 ? 447 PHE C C 1 ATOM 2984 O O . PHE A 1 382 ? -167.054 -154.820 184.996 1.00 92.23 ? 447 PHE C O 1 ATOM 2985 C CB . PHE A 1 382 ? -168.191 -157.015 187.167 1.00 88.06 ? 447 PHE C CB 1 ATOM 2986 C CG . PHE A 1 382 ? -168.269 -155.668 187.827 1.00 93.58 ? 447 PHE C CG 1 ATOM 2987 C CD1 . PHE A 1 382 ? -169.434 -154.923 187.772 1.00 92.58 ? 447 PHE C CD1 1 ATOM 2988 C CD2 . PHE A 1 382 ? -167.177 -155.145 188.510 1.00 97.09 ? 447 PHE C CD2 1 ATOM 2989 C CE1 . PHE A 1 382 ? -169.519 -153.678 188.383 1.00 94.01 ? 447 PHE C CE1 1 ATOM 2990 C CE2 . PHE A 1 382 ? -167.251 -153.898 189.126 1.00 93.46 ? 447 PHE C CE2 1 ATOM 2991 C CZ . PHE A 1 382 ? -168.426 -153.165 189.062 1.00 92.82 ? 447 PHE C CZ 1 ATOM 2992 N N . VAL A 1 383 ? -165.569 -156.366 185.641 1.00 90.56 ? 448 VAL C N 1 ATOM 2993 C CA . VAL A 1 383 ? -164.464 -155.450 185.445 1.00 93.68 ? 448 VAL C CA 1 ATOM 2994 C C . VAL A 1 383 ? -164.347 -155.084 183.969 1.00 92.57 ? 448 VAL C C 1 ATOM 2995 O O . VAL A 1 383 ? -164.000 -153.952 183.626 1.00 92.87 ? 448 VAL C O 1 ATOM 2996 C CB . VAL A 1 383 ? -163.132 -156.040 185.954 1.00 92.31 ? 448 VAL C CB 1 ATOM 2997 C CG1 . VAL A 1 383 ? -163.291 -156.512 187.380 1.00 92.13 ? 448 VAL C CG1 1 ATOM 2998 C CG2 . VAL A 1 383 ? -162.696 -157.173 185.077 1.00 96.15 ? 448 VAL C CG2 1 ATOM 2999 N N . ALA A 1 384 ? -164.675 -156.030 183.096 1.00 89.49 ? 449 ALA C N 1 ATOM 3000 C CA . ALA A 1 384 ? -164.601 -155.766 181.669 1.00 84.80 ? 449 ALA C CA 1 ATOM 3001 C C . ALA A 1 384 ? -165.575 -154.663 181.304 1.00 85.03 ? 449 ALA C C 1 ATOM 3002 O O . ALA A 1 384 ? -165.313 -153.845 180.420 1.00 88.23 ? 449 ALA C O 1 ATOM 3003 C CB . ALA A 1 384 ? -164.895 -157.014 180.883 1.00 85.50 ? 449 ALA C CB 1 ATOM 3004 N N . GLY A 1 385 ? -166.704 -154.632 181.996 1.00 85.82 ? 450 GLY C N 1 ATOM 3005 C CA . GLY A 1 385 ? -167.683 -153.602 181.728 1.00 86.21 ? 450 GLY C CA 1 ATOM 3006 C C . GLY A 1 385 ? -167.241 -152.288 182.313 1.00 85.17 ? 450 GLY C C 1 ATOM 3007 O O . GLY A 1 385 ? -167.438 -151.227 181.723 1.00 85.34 ? 450 GLY C O 1 ATOM 3008 N N . LEU A 1 386 ? -166.571 -152.374 183.454 1.00 89.35 ? 451 LEU C N 1 ATOM 3009 C CA . LEU A 1 386 ? -166.105 -151.185 184.154 1.00 89.33 ? 451 LEU C CA 1 ATOM 3010 C C . LEU A 1 386 ? -164.954 -150.520 183.394 1.00 88.43 ? 451 LEU C C 1 ATOM 3011 O O . LEU A 1 386 ? -164.988 -149.312 183.138 1.00 86.71 ? 451 LEU C O 1 ATOM 3012 C CB . LEU A 1 386 ? -165.671 -151.549 185.570 1.00 87.44 ? 451 LEU C CB 1 ATOM 3013 C CG . LEU A 1 386 ? -165.073 -150.470 186.465 1.00 85.85 ? 451 LEU C CG 1 ATOM 3014 C CD1 . LEU A 1 386 ? -166.132 -149.517 187.021 1.00 86.24 ? 451 LEU C CD1 1 ATOM 3015 C CD2 . LEU A 1 386 ? -164.291 -151.121 187.578 1.00 80.15 ? 451 LEU C CD2 1 ATOM 3016 N N . PHE A 1 387 ? -163.952 -151.306 183.011 1.00 80.98 ? 452 PHE C N 1 ATOM 3017 C CA . PHE A 1 387 ? -162.826 -150.755 182.292 1.00 82.52 ? 452 PHE C CA 1 ATOM 3018 C C . PHE A 1 387 ? -163.277 -150.281 180.923 1.00 89.86 ? 452 PHE C C 1 ATOM 3019 O O . PHE A 1 387 ? -162.652 -149.409 180.319 1.00 95.65 ? 452 PHE C O 1 ATOM 3020 C CB . PHE A 1 387 ? -161.696 -151.768 182.162 1.00 84.69 ? 452 PHE C CB 1 ATOM 3021 C CG . PHE A 1 387 ? -160.986 -152.043 183.451 1.00 86.06 ? 452 PHE C CG 1 ATOM 3022 C CD1 . PHE A 1 387 ? -161.328 -151.353 184.603 1.00 83.56 ? 452 PHE C CD1 1 ATOM 3023 C CD2 . PHE A 1 387 ? -159.973 -152.987 183.512 1.00 87.62 ? 452 PHE C CD2 1 ATOM 3024 C CE1 . PHE A 1 387 ? -160.689 -151.603 185.795 1.00 80.66 ? 452 PHE C CE1 1 ATOM 3025 C CE2 . PHE A 1 387 ? -159.323 -153.247 184.706 1.00 87.28 ? 452 PHE C CE2 1 ATOM 3026 C CZ . PHE A 1 387 ? -159.687 -152.552 185.852 1.00 81.63 ? 452 PHE C CZ 1 ATOM 3027 N N . SER A 1 388 ? -164.356 -150.862 180.416 1.00 90.22 ? 453 SER C N 1 ATOM 3028 C CA . SER A 1 388 ? -164.888 -150.402 179.147 1.00 88.48 ? 453 SER C CA 1 ATOM 3029 C C . SER A 1 388 ? -165.465 -149.007 179.306 1.00 88.85 ? 453 SER C C 1 ATOM 3030 O O . SER A 1 388 ? -165.229 -148.132 178.470 1.00 90.10 ? 453 SER C O 1 ATOM 3031 C CB . SER A 1 388 ? -165.945 -151.366 178.624 1.00 88.06 ? 453 SER C CB 1 ATOM 3032 O OG . SER A 1 388 ? -165.337 -152.568 178.194 1.00 82.57 ? 453 SER C OG 1 ATOM 3033 N N . LEU A 1 389 ? -166.208 -148.795 180.390 1.00 87.06 ? 454 LEU C N 1 ATOM 3034 C CA . LEU A 1 389 ? -166.756 -147.470 180.670 1.00 91.44 ? 454 LEU C CA 1 ATOM 3035 C C . LEU A 1 389 ? -165.612 -146.482 180.943 1.00 93.50 ? 454 LEU C C 1 ATOM 3036 O O . LEU A 1 389 ? -165.710 -145.296 180.598 1.00 92.51 ? 454 LEU C O 1 ATOM 3037 C CB . LEU A 1 389 ? -167.740 -147.514 181.843 1.00 83.74 ? 454 LEU C CB 1 ATOM 3038 C CG . LEU A 1 389 ? -168.406 -146.202 182.271 1.00 88.52 ? 454 LEU C CG 1 ATOM 3039 C CD1 . LEU A 1 389 ? -169.722 -146.448 182.968 1.00 89.06 ? 454 LEU C CD1 1 ATOM 3040 C CD2 . LEU A 1 389 ? -167.506 -145.443 183.216 1.00 94.36 ? 454 LEU C CD2 1 ATOM 3041 N N . TYR A 1 390 ? -164.523 -146.974 181.535 1.00 90.76 ? 455 TYR C N 1 ATOM 3042 C CA . TYR A 1 390 ? -163.331 -146.148 181.750 1.00 88.82 ? 455 TYR C CA 1 ATOM 3043 C C . TYR A 1 390 ? -162.704 -145.749 180.431 1.00 87.09 ? 455 TYR C C 1 ATOM 3044 O O . TYR A 1 390 ? -162.412 -144.579 180.199 1.00 92.84 ? 455 TYR C O 1 ATOM 3045 C CB . TYR A 1 390 ? -162.276 -146.889 182.585 1.00 85.79 ? 455 TYR C CB 1 ATOM 3046 C CG . TYR A 1 390 ? -162.614 -147.018 184.038 1.00 83.23 ? 455 TYR C CG 1 ATOM 3047 C CD1 . TYR A 1 390 ? -163.596 -146.222 184.602 1.00 84.98 ? 455 TYR C CD1 1 ATOM 3048 C CD2 . TYR A 1 390 ? -161.956 -147.937 184.848 1.00 85.31 ? 455 TYR C CD2 1 ATOM 3049 C CE1 . TYR A 1 390 ? -163.925 -146.335 185.937 1.00 88.86 ? 455 TYR C CE1 1 ATOM 3050 C CE2 . TYR A 1 390 ? -162.273 -148.056 186.191 1.00 87.93 ? 455 TYR C CE2 1 ATOM 3051 C CZ . TYR A 1 390 ? -163.262 -147.249 186.731 1.00 89.11 ? 455 TYR C CZ 1 ATOM 3052 O OH . TYR A 1 390 ? -163.588 -147.349 188.070 1.00 91.27 ? 455 TYR C OH 1 ATOM 3053 N N . PHE A 1 391 ? -162.487 -146.734 179.573 1.00 87.04 ? 456 PHE C N 1 ATOM 3054 C CA . PHE A 1 391 ? -161.824 -146.490 178.312 1.00 88.67 ? 456 PHE C CA 1 ATOM 3055 C C . PHE A 1 391 ? -162.635 -145.547 177.442 1.00 93.99 ? 456 PHE C C 1 ATOM 3056 O O . PHE A 1 391 ? -162.076 -144.713 176.729 1.00 94.98 ? 456 PHE C O 1 ATOM 3057 C CB . PHE A 1 391 ? -161.583 -147.792 177.569 1.00 82.01 ? 456 PHE C CB 1 ATOM 3058 C CG . PHE A 1 391 ? -161.012 -147.599 176.210 1.00 89.96 ? 456 PHE C CG 1 ATOM 3059 C CD1 . PHE A 1 391 ? -159.642 -147.515 176.031 1.00 96.33 ? 456 PHE C CD1 1 ATOM 3060 C CD2 . PHE A 1 391 ? -161.836 -147.489 175.105 1.00 91.99 ? 456 PHE C CD2 1 ATOM 3061 C CE1 . PHE A 1 391 ? -159.103 -147.330 174.769 1.00 93.47 ? 456 PHE C CE1 1 ATOM 3062 C CE2 . PHE A 1 391 ? -161.302 -147.302 173.839 1.00 95.00 ? 456 PHE C CE2 1 ATOM 3063 C CZ . PHE A 1 391 ? -159.935 -147.221 173.674 1.00 92.88 ? 456 PHE C CZ 1 ATOM 3064 N N . VAL A 1 392 ? -163.957 -145.659 177.514 1.00 93.82 ? 457 VAL C N 1 ATOM 3065 C CA . VAL A 1 392 ? -164.799 -144.858 176.638 1.00 91.85 ? 457 VAL C CA 1 ATOM 3066 C C . VAL A 1 392 ? -164.874 -143.423 177.125 1.00 88.45 ? 457 VAL C C 1 ATOM 3067 O O . VAL A 1 392 ? -164.598 -142.498 176.365 1.00 90.01 ? 457 VAL C O 1 ATOM 3068 C CB . VAL A 1 392 ? -166.214 -145.452 176.519 1.00 89.84 ? 457 VAL C CB 1 ATOM 3069 C CG1 . VAL A 1 392 ? -167.174 -144.433 175.938 1.00 83.92 ? 457 VAL C CG1 1 ATOM 3070 C CG2 . VAL A 1 392 ? -166.175 -146.712 175.669 1.00 80.30 ? 457 VAL C CG2 1 ATOM 3071 N N . VAL A 1 393 ? -165.194 -143.237 178.403 1.00 87.48 ? 458 VAL C N 1 ATOM 3072 C CA . VAL A 1 393 ? -165.210 -141.890 178.963 1.00 90.46 ? 458 VAL C CA 1 ATOM 3073 C C . VAL A 1 393 ? -163.805 -141.316 178.944 1.00 93.02 ? 458 VAL C C 1 ATOM 3074 O O . VAL A 1 393 ? -163.618 -140.109 178.780 1.00 93.34 ? 458 VAL C O 1 ATOM 3075 C CB . VAL A 1 393 ? -165.735 -141.845 180.405 1.00 92.49 ? 458 VAL C CB 1 ATOM 3076 C CG1 . VAL A 1 393 ? -165.552 -140.451 180.985 1.00 85.17 ? 458 VAL C CG1 1 ATOM 3077 C CG2 . VAL A 1 393 ? -167.199 -142.250 180.456 1.00 96.93 ? 458 VAL C CG2 1 ATOM 3078 N N . GLY A 1 394 ? -162.816 -142.199 179.048 1.00 89.86 ? 459 GLY C N 1 ATOM 3079 C CA . GLY A 1 394 ? -161.434 -141.773 179.131 1.00 89.75 ? 459 GLY C CA 1 ATOM 3080 C C . GLY A 1 394 ? -160.925 -141.254 177.803 1.00 90.42 ? 459 GLY C C 1 ATOM 3081 O O . GLY A 1 394 ? -159.917 -140.545 177.745 1.00 87.44 ? 459 GLY C O 1 ATOM 3082 N N . LEU A 1 395 ? -161.643 -141.572 176.730 1.00 93.55 ? 460 LEU C N 1 ATOM 3083 C CA . LEU A 1 395 ? -161.256 -141.101 175.409 1.00 86.45 ? 460 LEU C CA 1 ATOM 3084 C C . LEU A 1 395 ? -161.280 -139.567 175.394 1.00 85.35 ? 460 LEU C C 1 ATOM 3085 O O . LEU A 1 395 ? -160.607 -138.935 174.578 1.00 80.40 ? 460 LEU C O 1 ATOM 3086 C CB . LEU A 1 395 ? -162.185 -141.673 174.332 1.00 87.59 ? 460 LEU C CB 1 ATOM 3087 C CG . LEU A 1 395 ? -161.909 -143.093 173.824 1.00 91.80 ? 460 LEU C CG 1 ATOM 3088 C CD1 . LEU A 1 395 ? -163.035 -143.573 172.921 1.00 85.34 ? 460 LEU C CD1 1 ATOM 3089 C CD2 . LEU A 1 395 ? -160.581 -143.166 173.086 1.00 84.76 ? 460 LEU C CD2 1 ATOM 3090 N N . ALA A 1 396 ? -162.048 -138.971 176.304 1.00 85.27 ? 461 ALA C N 1 ATOM 3091 C CA . ALA A 1 396 ? -162.087 -137.521 176.410 1.00 79.20 ? 461 ALA C CA 1 ATOM 3092 C C . ALA A 1 396 ? -160.714 -136.956 176.745 1.00 82.48 ? 461 ALA C C 1 ATOM 3093 O O . ALA A 1 396 ? -160.337 -135.901 176.246 1.00 82.66 ? 461 ALA C O 1 ATOM 3094 C CB . ALA A 1 396 ? -163.087 -137.097 177.470 1.00 76.65 ? 461 ALA C CB 1 ATOM 3095 N N . SER A 1 397 ? -159.957 -137.672 177.572 1.00 81.28 ? 462 SER C N 1 ATOM 3096 C CA . SER A 1 397 ? -158.651 -137.181 178.002 1.00 81.07 ? 462 SER C CA 1 ATOM 3097 C C . SER A 1 397 ? -157.562 -137.508 176.973 1.00 81.92 ? 462 SER C C 1 ATOM 3098 O O . SER A 1 397 ? -156.416 -137.087 177.113 1.00 83.43 ? 462 SER C O 1 ATOM 3099 C CB . SER A 1 397 ? -158.294 -137.739 179.394 1.00 79.47 ? 462 SER C CB 1 ATOM 3100 O OG . SER A 1 397 ? -158.421 -139.150 179.440 1.00 89.68 ? 462 SER C OG 1 ATOM 3101 N N . CYS A 1 398 ? -157.916 -138.279 175.954 1.00 79.80 ? 463 CYS C N 1 ATOM 3102 C CA . CYS A 1 398 ? -157.014 -138.515 174.832 1.00 76.02 ? 463 CYS C CA 1 ATOM 3103 C C . CYS A 1 398 ? -157.226 -137.484 173.707 1.00 81.30 ? 463 CYS C C 1 ATOM 3104 O O . CYS A 1 398 ? -156.563 -137.539 172.664 1.00 78.11 ? 463 CYS C O 1 ATOM 3105 C CB . CYS A 1 398 ? -157.191 -139.926 174.285 1.00 81.34 ? 463 CYS C CB 1 ATOM 3106 S SG . CYS A 1 398 ? -156.840 -141.209 175.477 1.00 93.89 ? 463 CYS C SG 1 ATOM 3107 N N . THR A 1 399 ? -158.162 -136.560 173.908 1.00 79.26 ? 464 THR C N 1 ATOM 3108 C CA . THR A 1 399 ? -158.387 -135.476 172.951 1.00 80.97 ? 464 THR C CA 1 ATOM 3109 C C . THR A 1 399 ? -157.341 -134.377 173.091 1.00 80.25 ? 464 THR C C 1 ATOM 3110 O O . THR A 1 399 ? -156.581 -134.343 174.056 1.00 79.89 ? 464 THR C O 1 ATOM 3111 C CB . THR A 1 399 ? -159.772 -134.857 173.105 1.00 82.25 ? 464 THR C CB 1 ATOM 3112 O OG1 . THR A 1 399 ? -159.843 -134.128 174.339 1.00 79.72 ? 464 THR C OG1 1 ATOM 3113 C CG2 . THR A 1 399 ? -160.831 -135.944 173.073 1.00 84.51 ? 464 THR C CG2 1 ATOM 3114 N N . GLN A 1 400 ? -157.284 -133.498 172.099 1.00 82.30 ? 465 GLN C N 1 ATOM 3115 C CA . GLN A 1 400 ? -156.275 -132.447 172.062 1.00 76.47 ? 465 GLN C CA 1 ATOM 3116 C C . GLN A 1 400 ? -156.419 -131.498 173.226 1.00 74.59 ? 465 GLN C C 1 ATOM 3117 O O . GLN A 1 400 ? -155.434 -130.981 173.742 1.00 80.04 ? 465 GLN C O 1 ATOM 3118 C CB . GLN A 1 400 ? -156.364 -131.683 170.743 1.00 80.45 ? 465 GLN C CB 1 ATOM 3119 C CG . GLN A 1 400 ? -156.086 -132.561 169.528 1.00 81.13 ? 465 GLN C CG 1 ATOM 3120 C CD . GLN A 1 400 ? -156.324 -131.849 168.216 1.00 79.58 ? 465 GLN C CD 1 ATOM 3121 O OE1 . GLN A 1 400 ? -157.378 -131.239 167.998 1.00 81.33 ? 465 GLN C OE1 1 ATOM 3122 N NE2 . GLN A 1 400 ? -155.348 -131.934 167.323 1.00 80.67 ? 465 GLN C NE2 1 ATOM 3123 N N . GLY A 1 401 ? -157.651 -131.307 173.670 1.00 78.06 ? 466 GLY C N 1 ATOM 3124 C CA . GLY A 1 401 ? -157.915 -130.487 174.833 1.00 78.38 ? 466 GLY C CA 1 ATOM 3125 C C . GLY A 1 401 ? -157.933 -131.343 176.088 1.00 76.98 ? 466 GLY C C 1 ATOM 3126 O O . GLY A 1 401 ? -158.381 -130.898 177.152 1.00 75.28 ? 466 GLY C O 1 ATOM 3127 N N . GLY A 1 402 ? -157.449 -132.576 175.967 1.00 71.25 ? 467 GLY C N 1 ATOM 3128 C CA . GLY A 1 402 ? -157.607 -133.558 177.028 1.00 77.78 ? 467 GLY C CA 1 ATOM 3129 C C . GLY A 1 402 ? -156.971 -133.187 178.360 1.00 79.16 ? 467 GLY C C 1 ATOM 3130 O O . GLY A 1 402 ? -157.458 -133.577 179.423 1.00 75.95 ? 467 GLY C O 1 ATOM 3131 N N . PHE A 1 403 ? -155.885 -132.425 178.320 1.00 79.07 ? 468 PHE C N 1 ATOM 3132 C CA . PHE A 1 403 ? -155.274 -132.016 179.568 1.00 71.81 ? 468 PHE C CA 1 ATOM 3133 C C . PHE A 1 403 ? -156.251 -131.180 180.368 1.00 73.29 ? 468 PHE C C 1 ATOM 3134 O O . PHE A 1 403 ? -156.290 -131.285 181.591 1.00 77.91 ? 468 PHE C O 1 ATOM 3135 C CB . PHE A 1 403 ? -153.982 -131.224 179.330 1.00 72.67 ? 468 PHE C CB 1 ATOM 3136 C CG . PHE A 1 403 ? -153.187 -130.991 180.578 1.00 78.36 ? 468 PHE C CG 1 ATOM 3137 C CD1 . PHE A 1 403 ? -152.205 -131.891 180.971 1.00 77.59 ? 468 PHE C CD1 1 ATOM 3138 C CD2 . PHE A 1 403 ? -153.444 -129.891 181.385 1.00 82.02 ? 468 PHE C CD2 1 ATOM 3139 C CE1 . PHE A 1 403 ? -151.487 -131.691 182.144 1.00 73.22 ? 468 PHE C CE1 1 ATOM 3140 C CE2 . PHE A 1 403 ? -152.728 -129.684 182.562 1.00 81.41 ? 468 PHE C CE2 1 ATOM 3141 C CZ . PHE A 1 403 ? -151.749 -130.587 182.938 1.00 73.37 ? 468 PHE C CZ 1 ATOM 3142 N N . TYR A 1 404 ? -157.063 -130.376 179.684 1.00 74.18 ? 469 TYR C N 1 ATOM 3143 C CA . TYR A 1 404 ? -157.970 -129.467 180.382 1.00 77.40 ? 469 TYR C CA 1 ATOM 3144 C C . TYR A 1 404 ? -159.017 -130.282 181.123 1.00 75.36 ? 469 TYR C C 1 ATOM 3145 O O . TYR A 1 404 ? -159.544 -129.863 182.153 1.00 73.66 ? 469 TYR C O 1 ATOM 3146 C CB . TYR A 1 404 ? -158.636 -128.479 179.410 1.00 81.19 ? 469 TYR C CB 1 ATOM 3147 C CG . TYR A 1 404 ? -157.725 -127.409 178.818 1.00 79.29 ? 469 TYR C CG 1 ATOM 3148 C CD1 . TYR A 1 404 ? -157.023 -126.533 179.636 1.00 78.23 ? 469 TYR C CD1 1 ATOM 3149 C CD2 . TYR A 1 404 ? -157.599 -127.256 177.442 1.00 76.12 ? 469 TYR C CD2 1 ATOM 3150 C CE1 . TYR A 1 404 ? -156.206 -125.558 179.104 1.00 78.33 ? 469 TYR C CE1 1 ATOM 3151 C CE2 . TYR A 1 404 ? -156.785 -126.284 176.902 1.00 76.09 ? 469 TYR C CE2 1 ATOM 3152 C CZ . TYR A 1 404 ? -156.089 -125.437 177.735 1.00 79.54 ? 469 TYR C CZ 1 ATOM 3153 O OH . TYR A 1 404 ? -155.274 -124.464 177.194 1.00 80.82 ? 469 TYR C OH 1 ATOM 3154 N N . PHE A 1 405 ? -159.312 -131.452 180.565 1.00 78.08 ? 470 PHE C N 1 ATOM 3155 C CA . PHE A 1 405 ? -160.266 -132.389 181.153 1.00 79.90 ? 470 PHE C CA 1 ATOM 3156 C C . PHE A 1 405 ? -159.618 -133.119 182.321 1.00 78.00 ? 470 PHE C C 1 ATOM 3157 O O . PHE A 1 405 ? -160.201 -133.235 183.397 1.00 78.35 ? 470 PHE C O 1 ATOM 3158 C CB . PHE A 1 405 ? -160.747 -133.378 180.094 1.00 77.67 ? 470 PHE C CB 1 ATOM 3159 C CG . PHE A 1 405 ? -161.650 -134.445 180.624 1.00 80.96 ? 470 PHE C CG 1 ATOM 3160 C CD1 . PHE A 1 405 ? -162.957 -134.153 180.974 1.00 81.57 ? 470 PHE C CD1 1 ATOM 3161 C CD2 . PHE A 1 405 ? -161.198 -135.752 180.750 1.00 82.62 ? 470 PHE C CD2 1 ATOM 3162 C CE1 . PHE A 1 405 ? -163.794 -135.140 181.460 1.00 86.15 ? 470 PHE C CE1 1 ATOM 3163 C CE2 . PHE A 1 405 ? -162.031 -136.747 181.232 1.00 81.43 ? 470 PHE C CE2 1 ATOM 3164 C CZ . PHE A 1 405 ? -163.329 -136.442 181.589 1.00 83.93 ? 470 PHE C CZ 1 ATOM 3165 N N . PHE A 1 406 ? -158.386 -133.574 182.102 1.00 77.99 ? 471 PHE C N 1 ATOM 3166 C CA . PHE A 1 406 ? -157.602 -134.198 183.147 1.00 71.72 ? 471 PHE C CA 1 ATOM 3167 C C . PHE A 1 406 ? -157.496 -133.251 184.327 1.00 75.32 ? 471 PHE C C 1 ATOM 3168 O O . PHE A 1 406 ? -157.800 -133.622 185.458 1.00 78.54 ? 471 PHE C O 1 ATOM 3169 C CB . PHE A 1 406 ? -156.211 -134.567 182.628 1.00 73.05 ? 471 PHE C CB 1 ATOM 3170 C CG . PHE A 1 406 ? -155.214 -134.897 183.716 1.00 75.33 ? 471 PHE C CG 1 ATOM 3171 C CD1 . PHE A 1 406 ? -155.068 -136.200 184.171 1.00 80.09 ? 471 PHE C CD1 1 ATOM 3172 C CD2 . PHE A 1 406 ? -154.410 -133.912 184.261 1.00 74.69 ? 471 PHE C CD2 1 ATOM 3173 C CE1 . PHE A 1 406 ? -154.150 -136.510 185.163 1.00 77.65 ? 471 PHE C CE1 1 ATOM 3174 C CE2 . PHE A 1 406 ? -153.496 -134.211 185.256 1.00 80.17 ? 471 PHE C CE2 1 ATOM 3175 C CZ . PHE A 1 406 ? -153.364 -135.516 185.709 1.00 79.68 ? 471 PHE C CZ 1 ATOM 3176 N N . HIS A 1 407 ? -157.113 -132.010 184.054 1.00 72.86 ? 472 HIS C N 1 ATOM 3177 C CA . HIS A 1 407 ? -156.860 -131.060 185.125 1.00 72.89 ? 472 HIS C CA 1 ATOM 3178 C C . HIS A 1 407 ? -158.118 -130.763 185.930 1.00 76.92 ? 472 HIS C C 1 ATOM 3179 O O . HIS A 1 407 ? -158.051 -130.581 187.149 1.00 74.97 ? 472 HIS C O 1 ATOM 3180 C CB . HIS A 1 407 ? -156.283 -129.772 184.556 1.00 70.98 ? 472 HIS C CB 1 ATOM 3181 C CG . HIS A 1 407 ? -155.631 -128.905 185.582 1.00 74.58 ? 472 HIS C CG 1 ATOM 3182 N ND1 . HIS A 1 407 ? -155.969 -127.580 185.764 1.00 75.08 ? 472 HIS C ND1 1 ATOM 3183 C CD2 . HIS A 1 407 ? -154.677 -129.184 186.502 1.00 70.07 ? 472 HIS C CD2 1 ATOM 3184 C CE1 . HIS A 1 407 ? -155.240 -127.074 186.743 1.00 70.42 ? 472 HIS C CE1 1 ATOM 3185 N NE2 . HIS A 1 407 ? -154.450 -128.028 187.207 1.00 76.40 ? 472 HIS C NE2 1 ATOM 3186 N N . LEU A 1 408 ? -159.272 -130.770 185.262 1.00 80.61 ? 473 LEU C N 1 ATOM 3187 C CA . LEU A 1 408 ? -160.534 -130.507 185.953 1.00 79.85 ? 473 LEU C CA 1 ATOM 3188 C C . LEU A 1 408 ? -160.826 -131.593 186.983 1.00 81.17 ? 473 LEU C C 1 ATOM 3189 O O . LEU A 1 408 ? -161.042 -131.304 188.164 1.00 80.20 ? 473 LEU C O 1 ATOM 3190 C CB . LEU A 1 408 ? -161.700 -130.416 184.964 1.00 80.29 ? 473 LEU C CB 1 ATOM 3191 C CG . LEU A 1 408 ? -163.020 -130.005 185.626 1.00 77.42 ? 473 LEU C CG 1 ATOM 3192 C CD1 . LEU A 1 408 ? -162.902 -128.590 186.135 1.00 79.47 ? 473 LEU C CD1 1 ATOM 3193 C CD2 . LEU A 1 408 ? -164.184 -130.123 184.677 1.00 83.26 ? 473 LEU C CD2 1 ATOM 3194 N N . LEU A 1 409 ? -160.797 -132.847 186.534 1.00 78.76 ? 474 LEU C N 1 ATOM 3195 C CA . LEU A 1 409 ? -161.028 -133.960 187.440 1.00 79.69 ? 474 LEU C CA 1 ATOM 3196 C C . LEU A 1 409 ? -159.977 -133.996 188.541 1.00 80.85 ? 474 LEU C C 1 ATOM 3197 O O . LEU A 1 409 ? -160.298 -134.208 189.712 1.00 83.05 ? 474 LEU C O 1 ATOM 3198 C CB . LEU A 1 409 ? -161.013 -135.276 186.682 1.00 77.83 ? 474 LEU C CB 1 ATOM 3199 C CG . LEU A 1 409 ? -162.197 -135.472 185.761 1.00 83.64 ? 474 LEU C CG 1 ATOM 3200 C CD1 . LEU A 1 409 ? -162.135 -136.864 185.156 1.00 90.17 ? 474 LEU C CD1 1 ATOM 3201 C CD2 . LEU A 1 409 ? -163.457 -135.280 186.568 1.00 84.92 ? 474 LEU C CD2 1 ATOM 3202 N N . ASP A 1 410 ? -158.733 -133.712 188.172 1.00 76.18 ? 475 ASP C N 1 ATOM 3203 C CA . ASP A 1 410 ? -157.623 -133.853 189.099 1.00 79.76 ? 475 ASP C CA 1 ATOM 3204 C C . ASP A 1 410 ? -157.871 -132.965 190.299 1.00 80.64 ? 475 ASP C C 1 ATOM 3205 O O . ASP A 1 410 ? -157.458 -133.273 191.413 1.00 85.82 ? 475 ASP C O 1 ATOM 3206 C CB . ASP A 1 410 ? -156.296 -133.490 188.426 1.00 80.73 ? 475 ASP C CB 1 ATOM 3207 C CG . ASP A 1 410 ? -155.143 -133.435 189.408 1.00 83.00 ? 475 ASP C CG 1 ATOM 3208 O OD1 . ASP A 1 410 ? -154.986 -134.387 190.209 1.00 84.11 ? 475 ASP C OD1 1 ATOM 3209 O OD2 . ASP A 1 410 ? -154.408 -132.423 189.383 1.00 82.50 ? 475 ASP C OD2 1 ATOM 3210 N N . ARG A 1 411 ? -158.570 -131.866 190.063 1.00 81.31 ? 476 ARG C N 1 ATOM 3211 C CA . ARG A 1 411 ? -158.858 -130.926 191.127 1.00 81.61 ? 476 ARG C CA 1 ATOM 3212 C C . ARG A 1 411 ? -160.092 -131.276 191.927 1.00 85.11 ? 476 ARG C C 1 ATOM 3213 O O . ARG A 1 411 ? -160.089 -131.222 193.155 1.00 91.91 ? 476 ARG C O 1 ATOM 3214 C CB . ARG A 1 411 ? -159.029 -129.533 190.558 1.00 85.43 ? 476 ARG C CB 1 ATOM 3215 C CG . ARG A 1 411 ? -159.472 -128.539 191.589 1.00 91.29 ? 476 ARG C CG 1 ATOM 3216 C CD . ARG A 1 411 ? -158.587 -127.311 191.513 1.00 102.47 ? 476 ARG C CD 1 ATOM 3217 N NE . ARG A 1 411 ? -159.113 -126.229 192.332 1.00 108.53 ? 476 ARG C NE 1 ATOM 3218 C CZ . ARG A 1 411 ? -158.936 -124.939 192.066 1.00 104.88 ? 476 ARG C CZ 1 ATOM 3219 N NH1 . ARG A 1 411 ? -158.244 -124.557 190.993 1.00 104.18 ? 476 ARG C NH1 1 ATOM 3220 N NH2 . ARG A 1 411 ? -159.459 -124.032 192.876 1.00 106.49 ? 476 ARG C NH2 1 ATOM 3221 N N . TYR A 1 412 ? -161.153 -131.645 191.222 1.00 89.40 ? 477 TYR C N 1 ATOM 3222 C CA . TYR A 1 412 ? -162.467 -131.743 191.847 1.00 90.55 ? 477 TYR C CA 1 ATOM 3223 C C . TYR A 1 412 ? -162.902 -133.164 192.218 1.00 83.57 ? 477 TYR C C 1 ATOM 3224 O O . TYR A 1 412 ? -163.672 -133.350 193.154 1.00 86.45 ? 477 TYR C O 1 ATOM 3225 C CB . TYR A 1 412 ? -163.512 -131.095 190.923 1.00 89.94 ? 477 TYR C CB 1 ATOM 3226 C CG . TYR A 1 412 ? -163.435 -129.584 190.883 1.00 89.52 ? 477 TYR C CG 1 ATOM 3227 C CD1 . TYR A 1 412 ? -163.702 -128.835 192.022 1.00 92.12 ? 477 TYR C CD1 1 ATOM 3228 C CD2 . TYR A 1 412 ? -163.106 -128.905 189.713 1.00 87.94 ? 477 TYR C CD2 1 ATOM 3229 C CE1 . TYR A 1 412 ? -163.646 -127.456 192.014 1.00 93.21 ? 477 TYR C CE1 1 ATOM 3230 C CE2 . TYR A 1 412 ? -163.038 -127.509 189.693 1.00 92.91 ? 477 TYR C CE2 1 ATOM 3231 C CZ . TYR A 1 412 ? -163.313 -126.791 190.854 1.00 97.06 ? 477 TYR C CZ 1 ATOM 3232 O OH . TYR A 1 412 ? -163.256 -125.411 190.868 1.00 97.80 ? 477 TYR C OH 1 ATOM 3233 N N . ALA A 1 413 ? -162.394 -134.159 191.505 1.00 83.03 ? 478 ALA C N 1 ATOM 3234 C CA . ALA A 1 413 ? -162.902 -135.524 191.639 1.00 85.66 ? 478 ALA C CA 1 ATOM 3235 C C . ALA A 1 413 ? -162.790 -136.048 193.067 1.00 85.40 ? 478 ALA C C 1 ATOM 3236 O O . ALA A 1 413 ? -163.755 -136.559 193.637 1.00 88.61 ? 478 ALA C O 1 ATOM 3237 C CB . ALA A 1 413 ? -162.161 -136.455 190.695 1.00 80.65 ? 478 ALA C CB 1 ATOM 3238 N N . ALA A 1 414 ? -161.622 -135.891 193.663 1.00 80.16 ? 479 ALA C N 1 ATOM 3239 C CA . ALA A 1 414 ? -161.378 -136.556 194.923 1.00 80.06 ? 479 ALA C CA 1 ATOM 3240 C C . ALA A 1 414 ? -160.903 -135.631 196.022 1.00 85.04 ? 479 ALA C C 1 ATOM 3241 O O . ALA A 1 414 ? -161.039 -135.961 197.194 1.00 97.67 ? 479 ALA C O 1 ATOM 3242 C CB . ALA A 1 414 ? -160.371 -137.673 194.719 1.00 83.17 ? 479 ALA C CB 1 ATOM 3243 N N . GLY A 1 415 ? -160.350 -134.483 195.651 1.00 85.10 ? 480 GLY C N 1 ATOM 3244 C CA . GLY A 1 415 ? -159.680 -133.616 196.607 1.00 82.41 ? 480 GLY C CA 1 ATOM 3245 C C . GLY A 1 415 ? -160.465 -133.260 197.855 1.00 89.15 ? 480 GLY C C 1 ATOM 3246 O O . GLY A 1 415 ? -160.194 -133.776 198.939 1.00 89.76 ? 480 GLY C O 1 ATOM 3247 N N . TYR A 1 416 ? -161.426 -132.354 197.706 1.00 95.72 ? 481 TYR C N 1 ATOM 3248 C CA . TYR A 1 416 ? -162.258 -131.934 198.825 1.00 88.16 ? 481 TYR C CA 1 ATOM 3249 C C . TYR A 1 416 ? -163.159 -133.068 199.302 1.00 88.45 ? 481 TYR C C 1 ATOM 3250 O O . TYR A 1 416 ? -163.497 -133.144 200.484 1.00 88.42 ? 481 TYR C O 1 ATOM 3251 C CB . TYR A 1 416 ? -163.108 -130.720 198.432 1.00 93.12 ? 481 TYR C CB 1 ATOM 3252 C CG . TYR A 1 416 ? -162.293 -129.555 197.901 1.00 99.47 ? 481 TYR C CG 1 ATOM 3253 C CD1 . TYR A 1 416 ? -161.802 -128.569 198.763 1.00 96.27 ? 481 TYR C CD1 1 ATOM 3254 C CD2 . TYR A 1 416 ? -162.013 -129.442 196.533 1.00 97.71 ? 481 TYR C CD2 1 ATOM 3255 C CE1 . TYR A 1 416 ? -161.049 -127.504 198.279 1.00 99.29 ? 481 TYR C CE1 1 ATOM 3256 C CE2 . TYR A 1 416 ? -161.266 -128.381 196.033 1.00 99.53 ? 481 TYR C CE2 1 ATOM 3257 C CZ . TYR A 1 416 ? -160.784 -127.413 196.909 1.00 107.68 ? 481 TYR C CZ 1 ATOM 3258 O OH . TYR A 1 416 ? -160.035 -126.362 196.410 1.00 107.57 ? 481 TYR C OH 1 ATOM 3259 N N . SER A 1 417 ? -163.545 -133.958 198.392 1.00 88.35 ? 482 SER C N 1 ATOM 3260 C CA . SER A 1 417 ? -164.561 -134.951 198.734 1.00 85.76 ? 482 SER C CA 1 ATOM 3261 C C . SER A 1 417 ? -164.068 -135.962 199.764 1.00 91.60 ? 482 SER C C 1 ATOM 3262 O O . SER A 1 417 ? -164.734 -136.207 200.778 1.00 88.96 ? 482 SER C O 1 ATOM 3263 C CB . SER A 1 417 ? -165.024 -135.689 197.489 1.00 84.62 ? 482 SER C CB 1 ATOM 3264 O OG . SER A 1 417 ? -164.697 -134.948 196.328 1.00 95.53 ? 482 SER C OG 1 ATOM 3265 N N . ILE A 1 418 ? -162.892 -136.528 199.512 1.00 89.41 ? 483 ILE C N 1 ATOM 3266 C CA . ILE A 1 418 ? -162.386 -137.608 200.343 1.00 85.98 ? 483 ILE C CA 1 ATOM 3267 C C . ILE A 1 418 ? -162.077 -137.113 201.753 1.00 82.76 ? 483 ILE C C 1 ATOM 3268 O O . ILE A 1 418 ? -162.192 -137.862 202.716 1.00 85.44 ? 483 ILE C O 1 ATOM 3269 C CB . ILE A 1 418 ? -161.127 -138.261 199.704 1.00 89.42 ? 483 ILE C CB 1 ATOM 3270 C CG1 . ILE A 1 418 ? -160.869 -139.653 200.300 1.00 89.24 ? 483 ILE C CG1 1 ATOM 3271 C CG2 . ILE A 1 418 ? -159.916 -137.355 199.865 1.00 83.68 ? 483 ILE C CG2 1 ATOM 3272 C CD1 . ILE A 1 418 ? -162.015 -140.640 200.120 1.00 85.58 ? 483 ILE C CD1 1 ATOM 3273 N N . LEU A 1 419 ? -161.713 -135.846 201.880 1.00 79.60 ? 484 LEU C N 1 ATOM 3274 C CA . LEU A 1 419 ? -161.380 -135.313 203.196 1.00 79.23 ? 484 LEU C CA 1 ATOM 3275 C C . LEU A 1 419 ? -162.579 -135.312 204.124 1.00 82.15 ? 484 LEU C C 1 ATOM 3276 O O . LEU A 1 419 ? -162.431 -135.504 205.334 1.00 83.53 ? 484 LEU C O 1 ATOM 3277 C CB . LEU A 1 419 ? -160.815 -133.898 203.090 1.00 83.20 ? 484 LEU C CB 1 ATOM 3278 C CG . LEU A 1 419 ? -159.427 -133.774 202.457 1.00 88.04 ? 484 LEU C CG 1 ATOM 3279 C CD1 . LEU A 1 419 ? -159.162 -132.336 202.062 1.00 87.94 ? 484 LEU C CD1 1 ATOM 3280 C CD2 . LEU A 1 419 ? -158.367 -134.271 203.420 1.00 82.34 ? 484 LEU C CD2 1 ATOM 3281 N N . VAL A 1 420 ? -163.773 -135.100 203.578 1.00 82.68 ? 485 VAL C N 1 ATOM 3282 C CA . VAL A 1 420 ? -164.954 -135.092 204.434 1.00 85.07 ? 485 VAL C CA 1 ATOM 3283 C C . VAL A 1 420 ? -165.385 -136.524 204.678 1.00 82.68 ? 485 VAL C C 1 ATOM 3284 O O . VAL A 1 420 ? -165.867 -136.853 205.756 1.00 86.18 ? 485 VAL C O 1 ATOM 3285 C CB . VAL A 1 420 ? -166.139 -134.271 203.838 1.00 82.90 ? 485 VAL C CB 1 ATOM 3286 C CG1 . VAL A 1 420 ? -165.671 -132.892 203.413 1.00 74.09 ? 485 VAL C CG1 1 ATOM 3287 C CG2 . VAL A 1 420 ? -166.793 -135.020 202.690 1.00 90.77 ? 485 VAL C CG2 1 ATOM 3288 N N . ALA A 1 421 ? -165.185 -137.380 203.683 1.00 79.92 ? 486 ALA C N 1 ATOM 3289 C CA . ALA A 1 421 ? -165.493 -138.795 203.850 1.00 79.81 ? 486 ALA C CA 1 ATOM 3290 C C . ALA A 1 421 ? -164.646 -139.386 204.967 1.00 82.89 ? 486 ALA C C 1 ATOM 3291 O O . ALA A 1 421 ? -165.171 -140.006 205.894 1.00 87.53 ? 486 ALA C O 1 ATOM 3292 C CB . ALA A 1 421 ? -165.265 -139.551 202.578 1.00 78.29 ? 486 ALA C CB 1 ATOM 3293 N N . VAL A 1 422 ? -163.340 -139.167 204.899 1.00 80.34 ? 487 VAL C N 1 ATOM 3294 C CA . VAL A 1 422 ? -162.454 -139.693 205.918 1.00 80.49 ? 487 VAL C CA 1 ATOM 3295 C C . VAL A 1 422 ? -162.756 -139.042 207.253 1.00 80.78 ? 487 VAL C C 1 ATOM 3296 O O . VAL A 1 422 ? -162.609 -139.669 208.295 1.00 85.23 ? 487 VAL C O 1 ATOM 3297 C CB . VAL A 1 422 ? -160.959 -139.481 205.561 1.00 78.76 ? 487 VAL C CB 1 ATOM 3298 C CG1 . VAL A 1 422 ? -160.088 -139.786 206.765 1.00 81.04 ? 487 VAL C CG1 1 ATOM 3299 C CG2 . VAL A 1 422 ? -160.554 -140.342 204.390 1.00 78.24 ? 487 VAL C CG2 1 ATOM 3300 N N . PHE A 1 423 ? -163.202 -137.790 207.231 1.00 83.26 ? 488 PHE C N 1 ATOM 3301 C CA . PHE A 1 423 ? -163.478 -137.105 208.489 1.00 85.57 ? 488 PHE C CA 1 ATOM 3302 C C . PHE A 1 423 ? -164.624 -137.788 209.221 1.00 84.27 ? 488 PHE C C 1 ATOM 3303 O O . PHE A 1 423 ? -164.581 -137.955 210.436 1.00 76.88 ? 488 PHE C O 1 ATOM 3304 C CB . PHE A 1 423 ? -163.812 -135.631 208.261 1.00 83.28 ? 488 PHE C CB 1 ATOM 3305 C CG . PHE A 1 423 ? -164.266 -134.918 209.504 1.00 83.65 ? 488 PHE C CG 1 ATOM 3306 C CD1 . PHE A 1 423 ? -163.343 -134.461 210.433 1.00 84.92 ? 488 PHE C CD1 1 ATOM 3307 C CD2 . PHE A 1 423 ? -165.618 -134.711 209.749 1.00 84.78 ? 488 PHE C CD2 1 ATOM 3308 C CE1 . PHE A 1 423 ? -163.752 -133.805 211.584 1.00 82.34 ? 488 PHE C CE1 1 ATOM 3309 C CE2 . PHE A 1 423 ? -166.037 -134.056 210.897 1.00 82.29 ? 488 PHE C CE2 1 ATOM 3310 C CZ . PHE A 1 423 ? -165.102 -133.605 211.815 1.00 80.99 ? 488 PHE C CZ 1 ATOM 3311 N N . PHE A 1 424 ? -165.649 -138.188 208.475 1.00 86.91 ? 489 PHE C N 1 ATOM 3312 C CA . PHE A 1 424 ? -166.744 -138.946 209.058 1.00 85.97 ? 489 PHE C CA 1 ATOM 3313 C C . PHE A 1 424 ? -166.305 -140.355 209.415 1.00 86.21 ? 489 PHE C C 1 ATOM 3314 O O . PHE A 1 424 ? -166.801 -140.931 210.379 1.00 88.13 ? 489 PHE C O 1 ATOM 3315 C CB . PHE A 1 424 ? -167.939 -138.980 208.107 1.00 87.99 ? 489 PHE C CB 1 ATOM 3316 C CG . PHE A 1 424 ? -168.591 -137.645 207.926 1.00 93.31 ? 489 PHE C CG 1 ATOM 3317 C CD1 . PHE A 1 424 ? -168.539 -136.700 208.937 1.00 95.70 ? 489 PHE C CD1 1 ATOM 3318 C CD2 . PHE A 1 424 ? -169.237 -137.323 206.744 1.00 96.73 ? 489 PHE C CD2 1 ATOM 3319 C CE1 . PHE A 1 424 ? -169.126 -135.457 208.775 1.00 96.79 ? 489 PHE C CE1 1 ATOM 3320 C CE2 . PHE A 1 424 ? -169.824 -136.085 206.577 1.00 95.35 ? 489 PHE C CE2 1 ATOM 3321 C CZ . PHE A 1 424 ? -169.768 -135.151 207.594 1.00 90.83 ? 489 PHE C CZ 1 ATOM 3322 N N . GLU A 1 425 ? -165.360 -140.901 208.651 1.00 86.72 ? 490 GLU C N 1 ATOM 3323 C CA . GLU A 1 425 ? -164.811 -142.218 208.954 1.00 80.78 ? 490 GLU C CA 1 ATOM 3324 C C . GLU A 1 425 ? -164.133 -142.229 210.327 1.00 84.14 ? 490 GLU C C 1 ATOM 3325 O O . GLU A 1 425 ? -164.312 -143.159 211.117 1.00 86.23 ? 490 GLU C O 1 ATOM 3326 C CB . GLU A 1 425 ? -163.808 -142.640 207.882 1.00 79.56 ? 490 GLU C CB 1 ATOM 3327 C CG . GLU A 1 425 ? -164.424 -143.072 206.566 1.00 81.62 ? 490 GLU C CG 1 ATOM 3328 C CD . GLU A 1 425 ? -163.386 -143.636 205.607 1.00 86.16 ? 490 GLU C CD 1 ATOM 3329 O OE1 . GLU A 1 425 ? -162.323 -144.092 206.069 1.00 86.10 ? 490 GLU C OE1 1 ATOM 3330 O OE2 . GLU A 1 425 ? -163.627 -143.615 204.389 1.00 90.72 ? 490 GLU C OE2 1 ATOM 3331 N N . ALA A 1 426 ? -163.369 -141.179 210.613 1.00 81.93 ? 491 ALA C N 1 ATOM 3332 C CA . ALA A 1 426 ? -162.699 -141.062 211.899 1.00 82.55 ? 491 ALA C CA 1 ATOM 3333 C C . ALA A 1 426 ? -163.729 -140.902 213.007 1.00 87.57 ? 491 ALA C C 1 ATOM 3334 O O . ALA A 1 426 ? -163.664 -141.585 214.036 1.00 88.89 ? 491 ALA C O 1 ATOM 3335 C CB . ALA A 1 426 ? -161.745 -139.892 211.900 1.00 77.09 ? 491 ALA C CB 1 ATOM 3336 N N . ILE A 1 427 ? -164.681 -139.994 212.774 1.00 87.65 ? 492 ILE C N 1 ATOM 3337 C CA . ILE A 1 427 ? -165.726 -139.683 213.743 1.00 83.38 ? 492 ILE C CA 1 ATOM 3338 C C . ILE A 1 427 ? -166.618 -140.887 213.984 1.00 85.90 ? 492 ILE C C 1 ATOM 3339 O O . ILE A 1 427 ? -167.042 -141.131 215.112 1.00 89.71 ? 492 ILE C O 1 ATOM 3340 C CB . ILE A 1 427 ? -166.598 -138.491 213.279 1.00 83.49 ? 492 ILE C CB 1 ATOM 3341 C CG1 . ILE A 1 427 ? -165.777 -137.199 213.234 1.00 82.82 ? 492 ILE C CG1 1 ATOM 3342 C CG2 . ILE A 1 427 ? -167.777 -138.291 214.213 1.00 76.92 ? 492 ILE C CG2 1 ATOM 3343 C CD1 . ILE A 1 427 ? -165.265 -136.766 214.579 1.00 77.78 ? 492 ILE C CD1 1 ATOM 3344 N N . ALA A 1 428 ? -166.878 -141.654 212.930 1.00 85.42 ? 493 ALA C N 1 ATOM 3345 C CA . ALA A 1 428 ? -167.725 -142.841 213.047 1.00 86.29 ? 493 ALA C CA 1 ATOM 3346 C C . ALA A 1 428 ? -167.030 -143.884 213.890 1.00 90.23 ? 493 ALA C C 1 ATOM 3347 O O . ALA A 1 428 ? -167.617 -144.451 214.809 1.00 93.92 ? 493 ALA C O 1 ATOM 3348 C CB . ALA A 1 428 ? -168.064 -143.423 211.669 1.00 85.85 ? 493 ALA C CB 1 ATOM 3349 N N . VAL A 1 429 ? -165.763 -144.122 213.577 1.00 90.66 ? 494 VAL C N 1 ATOM 3350 C CA . VAL A 1 429 ? -165.013 -145.152 214.263 1.00 89.25 ? 494 VAL C CA 1 ATOM 3351 C C . VAL A 1 429 ? -164.817 -144.806 215.727 1.00 87.97 ? 494 VAL C C 1 ATOM 3352 O O . VAL A 1 429 ? -165.191 -145.580 216.596 1.00 92.32 ? 494 VAL C O 1 ATOM 3353 C CB . VAL A 1 429 ? -163.641 -145.373 213.607 1.00 87.69 ? 494 VAL C CB 1 ATOM 3354 C CG1 . VAL A 1 429 ? -162.784 -146.285 214.461 1.00 79.56 ? 494 VAL C CG1 1 ATOM 3355 C CG2 . VAL A 1 429 ? -163.810 -145.944 212.208 1.00 86.18 ? 494 VAL C CG2 1 ATOM 3356 N N . SER A 1 430 ? -164.255 -143.637 216.002 1.00 86.97 ? 495 SER C N 1 ATOM 3357 C CA . SER A 1 430 ? -163.889 -143.295 217.370 1.00 83.76 ? 495 SER C CA 1 ATOM 3358 C C . SER A 1 430 ? -165.056 -142.953 218.289 1.00 89.44 ? 495 SER C C 1 ATOM 3359 O O . SER A 1 430 ? -165.000 -143.238 219.483 1.00 92.05 ? 495 SER C O 1 ATOM 3360 C CB . SER A 1 430 ? -162.912 -142.125 217.363 1.00 87.27 ? 495 SER C CB 1 ATOM 3361 O OG . SER A 1 430 ? -161.672 -142.500 216.802 1.00 91.99 ? 495 SER C OG 1 ATOM 3362 N N . TRP A 1 431 ? -166.109 -142.344 217.747 1.00 90.74 ? 496 TRP C N 1 ATOM 3363 C CA . TRP A 1 431 ? -167.109 -141.696 218.593 1.00 87.67 ? 496 TRP C CA 1 ATOM 3364 C C . TRP A 1 431 ? -168.490 -142.322 218.512 1.00 88.98 ? 496 TRP C C 1 ATOM 3365 O O . TRP A 1 431 ? -169.235 -142.304 219.492 1.00 95.04 ? 496 TRP C O 1 ATOM 3366 C CB . TRP A 1 431 ? -167.225 -140.214 218.249 1.00 85.85 ? 496 TRP C CB 1 ATOM 3367 C CG . TRP A 1 431 ? -166.018 -139.384 218.594 1.00 87.35 ? 496 TRP C CG 1 ATOM 3368 C CD1 . TRP A 1 431 ? -165.026 -138.995 217.747 1.00 90.53 ? 496 TRP C CD1 1 ATOM 3369 C CD2 . TRP A 1 431 ? -165.698 -138.819 219.870 1.00 88.73 ? 496 TRP C CD2 1 ATOM 3370 N NE1 . TRP A 1 431 ? -164.103 -138.229 218.419 1.00 89.45 ? 496 TRP C NE1 1 ATOM 3371 C CE2 . TRP A 1 431 ? -164.495 -138.104 219.723 1.00 87.28 ? 496 TRP C CE2 1 ATOM 3372 C CE3 . TRP A 1 431 ? -166.314 -138.848 221.122 1.00 93.71 ? 496 TRP C CE3 1 ATOM 3373 C CZ2 . TRP A 1 431 ? -163.893 -137.425 220.780 1.00 93.09 ? 496 TRP C CZ2 1 ATOM 3374 C CZ3 . TRP A 1 431 ? -165.714 -138.179 222.174 1.00 97.77 ? 496 TRP C CZ3 1 ATOM 3375 C CH2 . TRP A 1 431 ? -164.511 -137.479 221.997 1.00 98.37 ? 496 TRP C CH2 1 ATOM 3376 N N . ILE A 1 432 ? -168.857 -142.857 217.356 1.00 86.82 ? 497 ILE C N 1 ATOM 3377 C CA . ILE A 1 432 ? -170.145 -143.533 217.257 1.00 85.12 ? 497 ILE C CA 1 ATOM 3378 C C . ILE A 1 432 ? -169.937 -144.992 217.623 1.00 89.88 ? 497 ILE C C 1 ATOM 3379 O O . ILE A 1 432 ? -170.494 -145.486 218.602 1.00 91.46 ? 497 ILE C O 1 ATOM 3380 C CB . ILE A 1 432 ? -170.766 -143.427 215.842 1.00 90.46 ? 497 ILE C CB 1 ATOM 3381 C CG1 . ILE A 1 432 ? -170.796 -141.966 215.353 1.00 89.81 ? 497 ILE C CG1 1 ATOM 3382 C CG2 . ILE A 1 432 ? -172.147 -144.075 215.811 1.00 86.42 ? 497 ILE C CG2 1 ATOM 3383 C CD1 . ILE A 1 432 ? -170.994 -140.934 216.463 1.00 88.48 ? 497 ILE C CD1 1 ATOM 3384 N N . TYR A 1 433 ? -169.120 -145.672 216.826 1.00 89.08 ? 498 TYR C N 1 ATOM 3385 C CA . TYR A 1 433 ? -168.772 -147.064 217.074 1.00 89.03 ? 498 TYR C CA 1 ATOM 3386 C C . TYR A 1 433 ? -168.001 -147.215 218.384 1.00 89.42 ? 498 TYR C C 1 ATOM 3387 O O . TYR A 1 433 ? -168.177 -148.190 219.107 1.00 90.12 ? 498 TYR C O 1 ATOM 3388 C CB . TYR A 1 433 ? -167.950 -147.605 215.905 1.00 90.03 ? 498 TYR C CB 1 ATOM 3389 C CG . TYR A 1 433 ? -167.649 -149.082 215.991 1.00 94.17 ? 498 TYR C CG 1 ATOM 3390 C CD1 . TYR A 1 433 ? -168.642 -150.028 215.764 1.00 91.21 ? 498 TYR C CD1 1 ATOM 3391 C CD2 . TYR A 1 433 ? -166.366 -149.534 216.290 1.00 88.39 ? 498 TYR C CD2 1 ATOM 3392 C CE1 . TYR A 1 433 ? -168.367 -151.382 215.844 1.00 89.60 ? 498 TYR C CE1 1 ATOM 3393 C CE2 . TYR A 1 433 ? -166.085 -150.884 216.370 1.00 84.62 ? 498 TYR C CE2 1 ATOM 3394 C CZ . TYR A 1 433 ? -167.085 -151.801 216.147 1.00 85.63 ? 498 TYR C CZ 1 ATOM 3395 O OH . TYR A 1 433 ? -166.784 -153.141 216.224 1.00 83.32 ? 498 TYR C OH 1 ATOM 3396 N N . GLY A 1 434 ? -167.175 -146.222 218.701 1.00 88.25 ? 499 GLY C N 1 ATOM 3397 C CA . GLY A 1 434 ? -166.390 -146.226 219.924 1.00 89.77 ? 499 GLY C CA 1 ATOM 3398 C C . GLY A 1 434 ? -164.976 -146.766 219.781 1.00 87.36 ? 499 GLY C C 1 ATOM 3399 O O . GLY A 1 434 ? -164.760 -147.795 219.129 1.00 82.74 ? 499 GLY C O 1 ATOM 3400 N N . THR A 1 435 ? -164.013 -146.077 220.397 1.00 84.67 ? 500 THR C N 1 ATOM 3401 C CA . THR A 1 435 ? -162.638 -146.569 220.445 1.00 86.50 ? 500 THR C CA 1 ATOM 3402 C C . THR A 1 435 ? -162.577 -147.836 221.285 1.00 87.56 ? 500 THR C C 1 ATOM 3403 O O . THR A 1 435 ? -161.766 -148.719 221.024 1.00 88.50 ? 500 THR C O 1 ATOM 3404 C CB . THR A 1 435 ? -161.645 -145.517 221.024 1.00 88.89 ? 500 THR C CB 1 ATOM 3405 O OG1 . THR A 1 435 ? -161.973 -145.231 222.387 1.00 89.77 ? 500 THR C OG1 1 ATOM 3406 C CG2 . THR A 1 435 ? -161.676 -144.232 220.211 1.00 93.75 ? 500 THR C CG2 1 ATOM 3407 N N . ASN A 1 436 ? -163.459 -147.922 222.279 1.00 90.04 ? 501 ASN C N 1 ATOM 3408 C CA . ASN A 1 436 ? -163.568 -149.099 223.126 1.00 80.89 ? 501 ASN C CA 1 ATOM 3409 C C . ASN A 1 436 ? -163.786 -150.350 222.319 1.00 86.57 ? 501 ASN C C 1 ATOM 3410 O O . ASN A 1 436 ? -163.042 -151.318 222.443 1.00 88.37 ? 501 ASN C O 1 ATOM 3411 C CB . ASN A 1 436 ? -164.737 -148.966 224.104 1.00 89.67 ? 501 ASN C CB 1 ATOM 3412 C CG . ASN A 1 436 ? -164.389 -148.165 225.338 1.00 99.73 ? 501 ASN C CG 1 ATOM 3413 O OD1 . ASN A 1 436 ? -163.214 -148.027 225.702 1.00 102.46 ? 501 ASN C OD1 1 ATOM 3414 N ND2 . ASN A 1 436 ? -165.416 -147.640 226.002 1.00 100.52 ? 501 ASN C ND2 1 ATOM 3415 N N . ARG A 1 437 ? -164.824 -150.333 221.490 1.00 88.49 ? 502 ARG C N 1 ATOM 3416 C CA . ARG A 1 437 ? -165.128 -151.506 220.702 1.00 87.22 ? 502 ARG C CA 1 ATOM 3417 C C . ARG A 1 437 ? -163.957 -151.785 219.774 1.00 86.61 ? 502 ARG C C 1 ATOM 3418 O O . ARG A 1 437 ? -163.515 -152.921 219.650 1.00 87.12 ? 502 ARG C O 1 ATOM 3419 C CB . ARG A 1 437 ? -166.426 -151.317 219.911 1.00 82.87 ? 502 ARG C CB 1 ATOM 3420 C CG . ARG A 1 437 ? -167.676 -151.216 220.766 1.00 86.12 ? 502 ARG C CG 1 ATOM 3421 C CD . ARG A 1 437 ? -168.928 -151.105 219.904 1.00 96.28 ? 502 ARG C CD 1 ATOM 3422 N NE . ARG A 1 437 ? -170.158 -151.060 220.690 1.00 103.43 ? 502 ARG C NE 1 ATOM 3423 C CZ . ARG A 1 437 ? -171.213 -150.312 220.383 1.00 104.93 ? 502 ARG C CZ 1 ATOM 3424 N NH1 . ARG A 1 437 ? -171.187 -149.533 219.312 1.00 101.12 ? 502 ARG C NH1 1 ATOM 3425 N NH2 . ARG A 1 437 ? -172.294 -150.335 221.154 1.00 116.59 ? 502 ARG C NH2 1 ATOM 3426 N N . PHE A 1 438 ? -163.411 -150.730 219.180 1.00 87.21 ? 503 PHE C N 1 ATOM 3427 C CA . PHE A 1 438 ? -162.381 -150.889 218.163 1.00 82.40 ? 503 PHE C CA 1 ATOM 3428 C C . PHE A 1 438 ? -161.112 -151.482 218.760 1.00 83.63 ? 503 PHE C C 1 ATOM 3429 O O . PHE A 1 438 ? -160.520 -152.396 218.182 1.00 82.71 ? 503 PHE C O 1 ATOM 3430 C CB . PHE A 1 438 ? -162.091 -149.538 217.504 1.00 82.12 ? 503 PHE C CB 1 ATOM 3431 C CG . PHE A 1 438 ? -161.272 -149.623 216.250 1.00 70.11 ? 503 PHE C CG 1 ATOM 3432 C CD1 . PHE A 1 438 ? -161.734 -150.313 215.149 1.00 75.11 ? 503 PHE C CD1 1 ATOM 3433 C CD2 . PHE A 1 438 ? -160.054 -148.975 216.164 1.00 76.56 ? 503 PHE C CD2 1 ATOM 3434 C CE1 . PHE A 1 438 ? -160.986 -150.380 213.985 1.00 78.97 ? 503 PHE C CE1 1 ATOM 3435 C CE2 . PHE A 1 438 ? -159.299 -149.029 215.013 1.00 77.94 ? 503 PHE C CE2 1 ATOM 3436 C CZ . PHE A 1 438 ? -159.765 -149.740 213.919 1.00 79.44 ? 503 PHE C CZ 1 ATOM 3437 N N . SER A 1 439 ? -160.711 -150.985 219.931 1.00 82.62 ? 504 SER C N 1 ATOM 3438 C CA . SER A 1 439 ? -159.509 -151.496 220.589 1.00 83.24 ? 504 SER C CA 1 ATOM 3439 C C . SER A 1 439 ? -159.668 -152.971 220.897 1.00 87.66 ? 504 SER C C 1 ATOM 3440 O O . SER A 1 439 ? -158.757 -153.774 220.678 1.00 91.39 ? 504 SER C O 1 ATOM 3441 C CB . SER A 1 439 ? -159.231 -150.743 221.881 1.00 78.28 ? 504 SER C CB 1 ATOM 3442 O OG . SER A 1 439 ? -159.235 -149.354 221.654 1.00 88.35 ? 504 SER C OG 1 ATOM 3443 N N . GLU A 1 440 ? -160.856 -153.316 221.377 1.00 81.33 ? 505 GLU C N 1 ATOM 3444 C CA . GLU A 1 440 ? -161.208 -154.688 221.675 1.00 79.07 ? 505 GLU C CA 1 ATOM 3445 C C . GLU A 1 440 ? -161.204 -155.552 220.416 1.00 83.60 ? 505 GLU C C 1 ATOM 3446 O O . GLU A 1 440 ? -160.824 -156.724 220.460 1.00 85.79 ? 505 GLU C O 1 ATOM 3447 C CB . GLU A 1 440 ? -162.577 -154.695 222.349 1.00 85.19 ? 505 GLU C CB 1 ATOM 3448 C CG . GLU A 1 440 ? -163.200 -156.034 222.607 1.00 84.75 ? 505 GLU C CG 1 ATOM 3449 C CD . GLU A 1 440 ? -164.550 -155.876 223.270 1.00 89.53 ? 505 GLU C CD 1 ATOM 3450 O OE1 . GLU A 1 440 ? -165.058 -154.732 223.305 1.00 92.60 ? 505 GLU C OE1 1 ATOM 3451 O OE2 . GLU A 1 440 ? -165.100 -156.883 223.762 1.00 91.54 ? 505 GLU C OE2 1 ATOM 3452 N N . ASP A 1 441 ? -161.595 -154.968 219.287 1.00 85.61 ? 506 ASP C N 1 ATOM 3453 C CA . ASP A 1 441 ? -161.566 -155.694 218.030 1.00 84.62 ? 506 ASP C CA 1 ATOM 3454 C C . ASP A 1 441 ? -160.117 -155.953 217.667 1.00 79.32 ? 506 ASP C C 1 ATOM 3455 O O . ASP A 1 441 ? -159.748 -157.046 217.253 1.00 79.46 ? 506 ASP C O 1 ATOM 3456 C CB . ASP A 1 441 ? -162.270 -154.908 216.915 1.00 86.87 ? 506 ASP C CB 1 ATOM 3457 C CG . ASP A 1 441 ? -163.727 -154.601 217.235 1.00 89.62 ? 506 ASP C CG 1 ATOM 3458 O OD1 . ASP A 1 441 ? -164.434 -155.518 217.701 1.00 90.99 ? 506 ASP C OD1 1 ATOM 3459 O OD2 . ASP A 1 441 ? -164.162 -153.444 217.018 1.00 89.73 ? 506 ASP C OD2 1 ATOM 3460 N N . ILE A 1 442 ? -159.285 -154.941 217.854 1.00 80.37 ? 507 ILE C N 1 ATOM 3461 C CA . ILE A 1 442 ? -157.898 -155.072 217.464 1.00 81.97 ? 507 ILE C CA 1 ATOM 3462 C C . ILE A 1 442 ? -157.172 -156.099 218.347 1.00 81.80 ? 507 ILE C C 1 ATOM 3463 O O . ILE A 1 442 ? -156.371 -156.890 217.840 1.00 78.24 ? 507 ILE C O 1 ATOM 3464 C CB . ILE A 1 442 ? -157.197 -153.700 217.485 1.00 80.29 ? 507 ILE C CB 1 ATOM 3465 C CG1 . ILE A 1 442 ? -157.574 -152.922 216.228 1.00 76.01 ? 507 ILE C CG1 1 ATOM 3466 C CG2 . ILE A 1 442 ? -155.690 -153.852 217.505 1.00 81.15 ? 507 ILE C CG2 1 ATOM 3467 C CD1 . ILE A 1 442 ? -157.450 -151.428 216.375 1.00 79.36 ? 507 ILE C CD1 1 ATOM 3468 N N . ARG A 1 443 ? -157.477 -156.143 219.644 1.00 82.85 ? 508 ARG C N 1 ATOM 3469 C CA . ARG A 1 443 ? -156.852 -157.167 220.482 1.00 80.57 ? 508 ARG C CA 1 ATOM 3470 C C . ARG A 1 443 ? -157.309 -158.561 220.107 1.00 79.24 ? 508 ARG C C 1 ATOM 3471 O O . ARG A 1 443 ? -156.509 -159.489 220.099 1.00 77.21 ? 508 ARG C O 1 ATOM 3472 C CB . ARG A 1 443 ? -157.144 -156.995 221.964 1.00 77.96 ? 508 ARG C CB 1 ATOM 3473 C CG . ARG A 1 443 ? -156.988 -158.353 222.675 1.00 75.25 ? 508 ARG C CG 1 ATOM 3474 C CD . ARG A 1 443 ? -157.193 -158.278 224.154 1.00 79.63 ? 508 ARG C CD 1 ATOM 3475 N NE . ARG A 1 443 ? -156.818 -159.507 224.867 1.00 81.08 ? 508 ARG C NE 1 ATOM 3476 C CZ . ARG A 1 443 ? -157.371 -160.704 224.688 1.00 80.90 ? 508 ARG C CZ 1 ATOM 3477 N NH1 . ARG A 1 443 ? -158.307 -160.882 223.772 1.00 84.65 ? 508 ARG C NH1 1 ATOM 3478 N NH2 . ARG A 1 443 ? -156.967 -161.732 225.417 1.00 74.87 ? 508 ARG C NH2 1 ATOM 3479 N N . ASP A 1 444 ? -158.586 -158.717 219.777 1.00 76.88 ? 509 ASP C N 1 ATOM 3480 C CA . ASP A 1 444 ? -159.060 -160.048 219.453 1.00 77.20 ? 509 ASP C CA 1 ATOM 3481 C C . ASP A 1 444 ? -158.311 -160.545 218.230 1.00 78.86 ? 509 ASP C C 1 ATOM 3482 O O . ASP A 1 444 ? -158.094 -161.748 218.076 1.00 79.02 ? 509 ASP C O 1 ATOM 3483 C CB . ASP A 1 444 ? -160.562 -160.082 219.208 1.00 74.73 ? 509 ASP C CB 1 ATOM 3484 C CG . ASP A 1 444 ? -161.102 -161.506 219.141 1.00 78.28 ? 509 ASP C CG 1 ATOM 3485 O OD1 . ASP A 1 444 ? -161.051 -162.219 220.171 1.00 74.61 ? 509 ASP C OD1 1 ATOM 3486 O OD2 . ASP A 1 444 ? -161.578 -161.914 218.064 1.00 79.81 ? 509 ASP C OD2 1 ATOM 3487 N N . MET A 1 445 ? -157.899 -159.613 217.374 1.00 76.64 ? 510 MET C N 1 ATOM 3488 C CA . MET A 1 445 ? -157.128 -159.971 216.197 1.00 75.66 ? 510 MET C CA 1 ATOM 3489 C C . MET A 1 445 ? -155.654 -160.202 216.536 1.00 77.78 ? 510 MET C C 1 ATOM 3490 O O . MET A 1 445 ? -155.131 -161.283 216.280 1.00 79.73 ? 510 MET C O 1 ATOM 3491 C CB . MET A 1 445 ? -157.258 -158.895 215.114 1.00 77.03 ? 510 MET C CB 1 ATOM 3492 C CG . MET A 1 445 ? -158.498 -159.010 214.228 1.00 76.37 ? 510 MET C CG 1 ATOM 3493 S SD . MET A 1 445 ? -158.560 -157.737 212.930 1.00 86.60 ? 510 MET C SD 1 ATOM 3494 C CE . MET A 1 445 ? -158.049 -156.274 213.830 1.00 73.73 ? 510 MET C CE 1 ATOM 3495 N N . ILE A 1 446 ? -154.987 -159.196 217.102 1.00 73.49 ? 511 ILE C N 1 ATOM 3496 C CA . ILE A 1 446 ? -153.525 -159.238 217.221 1.00 74.12 ? 511 ILE C CA 1 ATOM 3497 C C . ILE A 1 446 ? -153.031 -159.500 218.644 1.00 79.22 ? 511 ILE C C 1 ATOM 3498 O O . ILE A 1 446 ? -151.823 -159.564 218.894 1.00 76.59 ? 511 ILE C O 1 ATOM 3499 C CB . ILE A 1 446 ? -152.866 -157.932 216.706 1.00 72.64 ? 511 ILE C CB 1 ATOM 3500 C CG1 . ILE A 1 446 ? -153.107 -156.767 217.663 1.00 72.54 ? 511 ILE C CG1 1 ATOM 3501 C CG2 . ILE A 1 446 ? -153.342 -157.594 215.297 1.00 71.03 ? 511 ILE C CG2 1 ATOM 3502 C CD1 . ILE A 1 446 ? -152.567 -155.466 217.152 1.00 70.82 ? 511 ILE C CD1 1 ATOM 3503 N N . GLY A 1 447 ? -153.968 -159.646 219.572 1.00 77.39 ? 512 GLY C N 1 ATOM 3504 C CA . GLY A 1 447 ? -153.642 -160.076 220.917 1.00 70.31 ? 512 GLY C CA 1 ATOM 3505 C C . GLY A 1 447 ? -153.399 -158.967 221.908 1.00 71.15 ? 512 GLY C C 1 ATOM 3506 O O . GLY A 1 447 ? -153.285 -159.219 223.107 1.00 71.99 ? 512 GLY C O 1 ATOM 3507 N N . PHE A 1 448 ? -153.314 -157.734 221.436 1.00 73.31 ? 513 PHE C N 1 ATOM 3508 C CA . PHE A 1 448 ? -153.188 -156.634 222.381 1.00 75.92 ? 513 PHE C CA 1 ATOM 3509 C C . PHE A 1 448 ? -153.971 -155.421 221.928 1.00 78.52 ? 513 PHE C C 1 ATOM 3510 O O . PHE A 1 448 ? -154.149 -155.213 220.734 1.00 82.97 ? 513 PHE C O 1 ATOM 3511 C CB . PHE A 1 448 ? -151.722 -156.266 222.586 1.00 73.18 ? 513 PHE C CB 1 ATOM 3512 C CG . PHE A 1 448 ? -151.003 -155.930 221.318 1.00 74.92 ? 513 PHE C CG 1 ATOM 3513 C CD1 . PHE A 1 448 ? -150.881 -154.616 220.907 1.00 77.78 ? 513 PHE C CD1 1 ATOM 3514 C CD2 . PHE A 1 448 ? -150.446 -156.925 220.539 1.00 73.53 ? 513 PHE C CD2 1 ATOM 3515 C CE1 . PHE A 1 448 ? -150.217 -154.295 219.746 1.00 76.57 ? 513 PHE C CE1 1 ATOM 3516 C CE2 . PHE A 1 448 ? -149.790 -156.613 219.368 1.00 78.54 ? 513 PHE C CE2 1 ATOM 3517 C CZ . PHE A 1 448 ? -149.671 -155.291 218.971 1.00 75.46 ? 513 PHE C CZ 1 ATOM 3518 N N . PRO A 1 449 ? -154.446 -154.616 222.888 1.00 79.76 ? 514 PRO C N 1 ATOM 3519 C CA . PRO A 1 449 ? -155.073 -153.326 222.607 1.00 72.65 ? 514 PRO C CA 1 ATOM 3520 C C . PRO A 1 449 ? -154.068 -152.347 222.010 1.00 76.89 ? 514 PRO C C 1 ATOM 3521 O O . PRO A 1 449 ? -152.874 -152.429 222.329 1.00 75.73 ? 514 PRO C O 1 ATOM 3522 C CB . PRO A 1 449 ? -155.552 -152.854 223.986 1.00 73.92 ? 514 PRO C CB 1 ATOM 3523 C CG . PRO A 1 449 ? -154.638 -153.513 224.949 1.00 75.61 ? 514 PRO C CG 1 ATOM 3524 C CD . PRO A 1 449 ? -154.284 -154.843 224.337 1.00 78.84 ? 514 PRO C CD 1 ATOM 3525 N N . PRO A 1 450 ? -154.547 -151.428 221.162 1.00 81.61 ? 515 PRO C N 1 ATOM 3526 C CA . PRO A 1 450 ? -153.745 -150.302 220.691 1.00 77.32 ? 515 PRO C CA 1 ATOM 3527 C C . PRO A 1 450 ? -153.368 -149.429 221.876 1.00 77.86 ? 515 PRO C C 1 ATOM 3528 O O . PRO A 1 450 ? -154.160 -149.342 222.812 1.00 78.89 ? 515 PRO C O 1 ATOM 3529 C CB . PRO A 1 450 ? -154.698 -149.555 219.745 1.00 80.35 ? 515 PRO C CB 1 ATOM 3530 C CG . PRO A 1 450 ? -155.857 -150.481 219.514 1.00 75.65 ? 515 PRO C CG 1 ATOM 3531 C CD . PRO A 1 450 ? -155.951 -151.326 220.725 1.00 80.36 ? 515 PRO C CD 1 ATOM 3532 N N . GLY A 1 451 ? -152.194 -148.810 221.851 1.00 80.30 ? 516 GLY C N 1 ATOM 3533 C CA . GLY A 1 451 ? -151.781 -147.958 222.948 1.00 83.92 ? 516 GLY C CA 1 ATOM 3534 C C . GLY A 1 451 ? -152.689 -146.747 223.077 1.00 86.17 ? 516 GLY C C 1 ATOM 3535 O O . GLY A 1 451 ? -153.456 -146.443 222.165 1.00 88.51 ? 516 GLY C O 1 ATOM 3536 N N . ARG A 1 452 ? -152.636 -146.060 224.214 1.00 86.10 ? 517 ARG C N 1 ATOM 3537 C CA . ARG A 1 452 ? -153.461 -144.871 224.382 1.00 91.83 ? 517 ARG C CA 1 ATOM 3538 C C . ARG A 1 452 ? -153.025 -143.802 223.381 1.00 92.42 ? 517 ARG C C 1 ATOM 3539 O O . ARG A 1 452 ? -153.791 -142.892 223.061 1.00 93.82 ? 517 ARG C O 1 ATOM 3540 C CB . ARG A 1 452 ? -153.403 -144.348 225.819 1.00 92.51 ? 517 ARG C CB 1 ATOM 3541 C CG . ARG A 1 452 ? -154.125 -145.259 226.821 1.00 113.83 ? 517 ARG C CG 1 ATOM 3542 C CD . ARG A 1 452 ? -154.315 -144.598 228.184 1.00 122.95 ? 517 ARG C CD 1 ATOM 3543 N NE . ARG A 1 452 ? -155.049 -143.334 228.086 1.00 128.78 ? 517 ARG C NE 1 ATOM 3544 C CZ . ARG A 1 452 ? -156.366 -143.210 228.236 1.00 128.55 ? 517 ARG C CZ 1 ATOM 3545 N NH1 . ARG A 1 452 ? -157.114 -144.278 228.497 1.00 133.61 ? 517 ARG C NH1 1 ATOM 3546 N NH2 . ARG A 1 452 ? -156.933 -142.013 228.129 1.00 122.25 ? 517 ARG C NH2 1 ATOM 3547 N N . TYR A 1 453 ? -151.799 -143.909 222.878 1.00 86.84 ? 518 TYR C N 1 ATOM 3548 C CA . TYR A 1 453 ? -151.355 -142.998 221.829 1.00 88.48 ? 518 TYR C CA 1 ATOM 3549 C C . TYR A 1 453 ? -152.222 -143.087 220.569 1.00 89.56 ? 518 TYR C C 1 ATOM 3550 O O . TYR A 1 453 ? -152.725 -142.082 220.073 1.00 89.67 ? 518 TYR C O 1 ATOM 3551 C CB . TYR A 1 453 ? -149.904 -143.282 221.461 1.00 90.81 ? 518 TYR C CB 1 ATOM 3552 C CG . TYR A 1 453 ? -149.438 -142.487 220.274 1.00 88.96 ? 518 TYR C CG 1 ATOM 3553 C CD1 . TYR A 1 453 ? -149.193 -141.136 220.391 1.00 92.42 ? 518 TYR C CD1 1 ATOM 3554 C CD2 . TYR A 1 453 ? -149.252 -143.082 219.041 1.00 90.70 ? 518 TYR C CD2 1 ATOM 3555 C CE1 . TYR A 1 453 ? -148.772 -140.393 219.321 1.00 94.69 ? 518 TYR C CE1 1 ATOM 3556 C CE2 . TYR A 1 453 ? -148.831 -142.347 217.958 1.00 94.57 ? 518 TYR C CE2 1 ATOM 3557 C CZ . TYR A 1 453 ? -148.591 -140.996 218.107 1.00 93.18 ? 518 TYR C CZ 1 ATOM 3558 O OH . TYR A 1 453 ? -148.169 -140.237 217.041 1.00 95.55 ? 518 TYR C OH 1 ATOM 3559 N N . TRP A 1 454 ? -152.410 -144.297 220.063 1.00 87.72 ? 519 TRP C N 1 ATOM 3560 C CA . TRP A 1 454 ? -153.215 -144.483 218.864 1.00 90.42 ? 519 TRP C CA 1 ATOM 3561 C C . TRP A 1 454 ? -154.662 -144.099 219.123 1.00 90.39 ? 519 TRP C C 1 ATOM 3562 O O . TRP A 1 454 ? -155.386 -143.714 218.203 1.00 91.59 ? 519 TRP C O 1 ATOM 3563 C CB . TRP A 1 454 ? -153.137 -145.930 218.377 1.00 87.22 ? 519 TRP C CB 1 ATOM 3564 C CG . TRP A 1 454 ? -151.766 -146.336 217.977 1.00 84.64 ? 519 TRP C CG 1 ATOM 3565 C CD1 . TRP A 1 454 ? -150.947 -147.222 218.612 1.00 85.20 ? 519 TRP C CD1 1 ATOM 3566 C CD2 . TRP A 1 454 ? -151.041 -145.856 216.848 1.00 85.51 ? 519 TRP C CD2 1 ATOM 3567 N NE1 . TRP A 1 454 ? -149.759 -147.327 217.937 1.00 86.45 ? 519 TRP C NE1 1 ATOM 3568 C CE2 . TRP A 1 454 ? -149.793 -146.494 216.850 1.00 84.92 ? 519 TRP C CE2 1 ATOM 3569 C CE3 . TRP A 1 454 ? -151.328 -144.940 215.838 1.00 87.84 ? 519 TRP C CE3 1 ATOM 3570 C CZ2 . TRP A 1 454 ? -148.831 -146.247 215.878 1.00 89.10 ? 519 TRP C CZ2 1 ATOM 3571 C CZ3 . TRP A 1 454 ? -150.373 -144.693 214.875 1.00 85.78 ? 519 TRP C CZ3 1 ATOM 3572 C CH2 . TRP A 1 454 ? -149.140 -145.344 214.901 1.00 84.30 ? 519 TRP C CH2 1 ATOM 3573 N N . GLN A 1 455 ? -155.082 -144.223 220.379 1.00 90.10 ? 520 GLN C N 1 ATOM 3574 C CA . GLN A 1 455 ? -156.463 -143.939 220.740 1.00 88.88 ? 520 GLN C CA 1 ATOM 3575 C C . GLN A 1 455 ? -156.710 -142.442 220.770 1.00 89.54 ? 520 GLN C C 1 ATOM 3576 O O . GLN A 1 455 ? -157.717 -141.960 220.248 1.00 90.23 ? 520 GLN C O 1 ATOM 3577 C CB . GLN A 1 455 ? -156.800 -144.555 222.089 1.00 93.44 ? 520 GLN C CB 1 ATOM 3578 C CG . GLN A 1 455 ? -156.764 -146.076 222.101 1.00 97.65 ? 520 GLN C CG 1 ATOM 3579 C CD . GLN A 1 455 ? -157.220 -146.665 223.421 1.00 94.18 ? 520 GLN C CD 1 ATOM 3580 O OE1 . GLN A 1 455 ? -157.168 -146.006 224.463 1.00 96.72 ? 520 GLN C OE1 1 ATOM 3581 N NE2 . GLN A 1 455 ? -157.672 -147.916 223.383 1.00 89.78 ? 520 GLN C NE2 1 ATOM 3582 N N . VAL A 1 456 ? -155.775 -141.705 221.364 1.00 90.13 ? 521 VAL C N 1 ATOM 3583 C CA . VAL A 1 456 ? -155.901 -140.255 221.431 1.00 90.39 ? 521 VAL C CA 1 ATOM 3584 C C . VAL A 1 456 ? -155.881 -139.677 220.026 1.00 94.45 ? 521 VAL C C 1 ATOM 3585 O O . VAL A 1 456 ? -156.622 -138.737 219.722 1.00 96.23 ? 521 VAL C O 1 ATOM 3586 C CB . VAL A 1 456 ? -154.770 -139.610 222.243 1.00 87.03 ? 521 VAL C CB 1 ATOM 3587 C CG1 . VAL A 1 456 ? -154.947 -138.112 222.268 1.00 86.83 ? 521 VAL C CG1 1 ATOM 3588 C CG2 . VAL A 1 456 ? -154.726 -140.171 223.657 1.00 79.94 ? 521 VAL C CG2 1 ATOM 3589 N N . CYS A 1 457 ? -155.056 -140.269 219.163 1.00 91.06 ? 522 CYS C N 1 ATOM 3590 C CA . CYS A 1 457 ? -154.902 -139.779 217.803 1.00 89.47 ? 522 CYS C CA 1 ATOM 3591 C C . CYS A 1 457 ? -156.166 -139.973 216.971 1.00 88.17 ? 522 CYS C C 1 ATOM 3592 O O . CYS A 1 457 ? -156.525 -139.103 216.179 1.00 88.73 ? 522 CYS C O 1 ATOM 3593 C CB . CYS A 1 457 ? -153.719 -140.467 217.122 1.00 84.07 ? 522 CYS C CB 1 ATOM 3594 S SG . CYS A 1 457 ? -152.102 -139.710 217.455 1.00 88.05 ? 522 CYS C SG 1 ATOM 3595 N N . TRP A 1 458 ? -156.839 -141.107 217.147 1.00 83.15 ? 523 TRP C N 1 ATOM 3596 C CA . TRP A 1 458 ? -158.038 -141.392 216.367 1.00 85.13 ? 523 TRP C CA 1 ATOM 3597 C C . TRP A 1 458 ? -159.211 -140.562 216.847 1.00 93.41 ? 523 TRP C C 1 ATOM 3598 O O . TRP A 1 458 ? -160.080 -140.174 216.060 1.00 90.69 ? 523 TRP C O 1 ATOM 3599 C CB . TRP A 1 458 ? -158.419 -142.866 216.456 1.00 83.72 ? 523 TRP C CB 1 ATOM 3600 C CG . TRP A 1 458 ? -157.461 -143.778 215.804 1.00 85.10 ? 523 TRP C CG 1 ATOM 3601 C CD1 . TRP A 1 458 ? -156.659 -143.499 214.738 1.00 86.66 ? 523 TRP C CD1 1 ATOM 3602 C CD2 . TRP A 1 458 ? -157.175 -145.127 216.178 1.00 85.83 ? 523 TRP C CD2 1 ATOM 3603 N NE1 . TRP A 1 458 ? -155.897 -144.592 214.417 1.00 79.37 ? 523 TRP C NE1 1 ATOM 3604 C CE2 . TRP A 1 458 ? -156.191 -145.606 215.290 1.00 84.45 ? 523 TRP C CE2 1 ATOM 3605 C CE3 . TRP A 1 458 ? -157.653 -145.979 217.179 1.00 84.76 ? 523 TRP C CE3 1 ATOM 3606 C CZ2 . TRP A 1 458 ? -155.682 -146.901 215.371 1.00 83.59 ? 523 TRP C CZ2 1 ATOM 3607 C CZ3 . TRP A 1 458 ? -157.154 -147.260 217.255 1.00 80.93 ? 523 TRP C CZ3 1 ATOM 3608 C CH2 . TRP A 1 458 ? -156.177 -147.710 216.362 1.00 86.01 ? 523 TRP C CH2 1 ATOM 3609 N N . ARG A 1 459 ? -159.242 -140.319 218.156 1.00 92.72 ? 524 ARG C N 1 ATOM 3610 C CA . ARG A 1 459 ? -160.385 -139.683 218.789 1.00 92.18 ? 524 ARG C CA 1 ATOM 3611 C C . ARG A 1 459 ? -160.320 -138.165 218.648 1.00 93.08 ? 524 ARG C C 1 ATOM 3612 O O . ARG A 1 459 ? -161.324 -137.518 218.361 1.00 93.71 ? 524 ARG C O 1 ATOM 3613 C CB . ARG A 1 459 ? -160.458 -140.100 220.268 1.00 96.42 ? 524 ARG C CB 1 ATOM 3614 C CG . ARG A 1 459 ? -161.655 -139.534 221.042 1.00 98.11 ? 524 ARG C CG 1 ATOM 3615 C CD . ARG A 1 459 ? -161.721 -140.044 222.487 1.00 98.61 ? 524 ARG C CD 1 ATOM 3616 N NE . ARG A 1 459 ? -162.126 -141.446 222.538 1.00 103.29 ? 524 ARG C NE 1 ATOM 3617 C CZ . ARG A 1 459 ? -163.387 -141.866 222.467 1.00 98.48 ? 524 ARG C CZ 1 ATOM 3618 N NH1 . ARG A 1 459 ? -164.379 -140.989 222.350 1.00 95.95 ? 524 ARG C NH1 1 ATOM 3619 N NH2 . ARG A 1 459 ? -163.656 -143.166 222.511 1.00 94.19 ? 524 ARG C NH2 1 ATOM 3620 N N . PHE A 1 460 ? -159.130 -137.603 218.817 1.00 92.11 ? 525 PHE C N 1 ATOM 3621 C CA . PHE A 1 460 ? -158.978 -136.154 218.865 1.00 92.98 ? 525 PHE C CA 1 ATOM 3622 C C . PHE A 1 460 ? -158.132 -135.609 217.719 1.00 93.90 ? 525 PHE C C 1 ATOM 3623 O O . PHE A 1 460 ? -158.586 -134.762 216.950 1.00 96.94 ? 525 PHE C O 1 ATOM 3624 C CB . PHE A 1 460 ? -158.355 -135.737 220.198 1.00 96.78 ? 525 PHE C CB 1 ATOM 3625 C CG . PHE A 1 460 ? -159.235 -135.990 221.392 1.00 98.96 ? 525 PHE C CG 1 ATOM 3626 C CD1 . PHE A 1 460 ? -160.608 -135.800 221.320 1.00 94.66 ? 525 PHE C CD1 1 ATOM 3627 C CD2 . PHE A 1 460 ? -158.685 -136.413 222.588 1.00 98.61 ? 525 PHE C CD2 1 ATOM 3628 C CE1 . PHE A 1 460 ? -161.414 -136.035 222.421 1.00 93.52 ? 525 PHE C CE1 1 ATOM 3629 C CE2 . PHE A 1 460 ? -159.485 -136.642 223.692 1.00 99.57 ? 525 PHE C CE2 1 ATOM 3630 C CZ . PHE A 1 460 ? -160.850 -136.455 223.608 1.00 97.48 ? 525 PHE C CZ 1 ATOM 3631 N N . VAL A 1 461 ? -156.895 -136.091 217.614 1.00 94.52 ? 526 VAL C N 1 ATOM 3632 C CA . VAL A 1 461 ? -155.948 -135.539 216.655 1.00 87.80 ? 526 VAL C CA 1 ATOM 3633 C C . VAL A 1 461 ? -156.416 -135.698 215.224 1.00 89.28 ? 526 VAL C C 1 ATOM 3634 O O . VAL A 1 461 ? -156.387 -134.744 214.453 1.00 90.53 ? 526 VAL C O 1 ATOM 3635 C CB . VAL A 1 461 ? -154.561 -136.195 216.778 1.00 86.44 ? 526 VAL C CB 1 ATOM 3636 C CG1 . VAL A 1 461 ? -153.545 -135.439 215.916 1.00 81.57 ? 526 VAL C CG1 1 ATOM 3637 C CG2 . VAL A 1 461 ? -154.113 -136.228 218.223 1.00 85.66 ? 526 VAL C CG2 1 ATOM 3638 N N . ALA A 1 462 ? -156.864 -136.894 214.872 1.00 90.37 ? 527 ALA C N 1 ATOM 3639 C CA . ALA A 1 462 ? -157.186 -137.182 213.483 1.00 88.88 ? 527 ALA C CA 1 ATOM 3640 C C . ALA A 1 462 ? -158.242 -136.243 212.917 1.00 89.16 ? 527 ALA C C 1 ATOM 3641 O O . ALA A 1 462 ? -158.021 -135.610 211.893 1.00 90.04 ? 527 ALA C O 1 ATOM 3642 C CB . ALA A 1 462 ? -157.663 -138.623 213.353 1.00 89.06 ? 527 ALA C CB 1 ATOM 3643 N N . PRO A 1 463 ? -159.399 -136.148 213.595 1.00 93.06 ? 528 PRO C N 1 ATOM 3644 C CA . PRO A 1 463 ? -160.477 -135.306 213.066 1.00 92.09 ? 528 PRO C CA 1 ATOM 3645 C C . PRO A 1 463 ? -160.088 -133.837 212.881 1.00 93.00 ? 528 PRO C C 1 ATOM 3646 O O . PRO A 1 463 ? -160.561 -133.212 211.921 1.00 95.41 ? 528 PRO C O 1 ATOM 3647 C CB . PRO A 1 463 ? -161.580 -135.445 214.118 1.00 90.62 ? 528 PRO C CB 1 ATOM 3648 C CG . PRO A 1 463 ? -161.275 -136.728 214.811 1.00 94.74 ? 528 PRO C CG 1 ATOM 3649 C CD . PRO A 1 463 ? -159.785 -136.833 214.836 1.00 90.32 ? 528 PRO C CD 1 ATOM 3650 N N . ILE A 1 464 ? -159.262 -133.283 213.767 1.00 85.10 ? 529 ILE C N 1 ATOM 3651 C CA . ILE A 1 464 ? -158.880 -131.886 213.588 1.00 88.16 ? 529 ILE C CA 1 ATOM 3652 C C . ILE A 1 464 ? -157.682 -131.805 212.648 1.00 91.81 ? 529 ILE C C 1 ATOM 3653 O O . ILE A 1 464 ? -157.367 -130.748 212.120 1.00 95.16 ? 529 ILE C O 1 ATOM 3654 C CB . ILE A 1 464 ? -158.587 -131.197 214.927 1.00 89.74 ? 529 ILE C CB 1 ATOM 3655 C CG1 . ILE A 1 464 ? -157.113 -131.308 215.307 1.00 88.62 ? 529 ILE C CG1 1 ATOM 3656 C CG2 . ILE A 1 464 ? -159.496 -131.760 216.019 1.00 89.00 ? 529 ILE C CG2 1 ATOM 3657 C CD1 . ILE A 1 464 ? -156.875 -131.116 216.807 1.00 95.13 ? 529 ILE C CD1 1 ATOM 3658 N N . PHE A 1 465 ? -157.030 -132.938 212.423 1.00 91.90 ? 530 PHE C N 1 ATOM 3659 C CA . PHE A 1 465 ? -155.997 -133.026 211.405 1.00 86.42 ? 530 PHE C CA 1 ATOM 3660 C C . PHE A 1 465 ? -156.663 -132.871 210.051 1.00 84.26 ? 530 PHE C C 1 ATOM 3661 O O . PHE A 1 465 ? -156.268 -132.040 209.243 1.00 84.87 ? 530 PHE C O 1 ATOM 3662 C CB . PHE A 1 465 ? -155.260 -134.368 211.508 1.00 84.92 ? 530 PHE C CB 1 ATOM 3663 C CG . PHE A 1 465 ? -154.346 -134.666 210.346 1.00 82.92 ? 530 PHE C CG 1 ATOM 3664 C CD1 . PHE A 1 465 ? -153.083 -134.093 210.274 1.00 80.68 ? 530 PHE C CD1 1 ATOM 3665 C CD2 . PHE A 1 465 ? -154.736 -135.543 209.342 1.00 80.90 ? 530 PHE C CD2 1 ATOM 3666 C CE1 . PHE A 1 465 ? -152.231 -134.376 209.216 1.00 80.57 ? 530 PHE C CE1 1 ATOM 3667 C CE2 . PHE A 1 465 ? -153.888 -135.826 208.278 1.00 77.12 ? 530 PHE C CE2 1 ATOM 3668 C CZ . PHE A 1 465 ? -152.636 -135.242 208.216 1.00 73.16 ? 530 PHE C CZ 1 ATOM 3669 N N . LEU A 1 466 ? -157.698 -133.670 209.827 1.00 86.15 ? 531 LEU C N 1 ATOM 3670 C CA . LEU A 1 466 ? -158.443 -133.616 208.584 1.00 84.88 ? 531 LEU C CA 1 ATOM 3671 C C . LEU A 1 466 ? -159.127 -132.268 208.477 1.00 87.45 ? 531 LEU C C 1 ATOM 3672 O O . LEU A 1 466 ? -159.235 -131.692 207.396 1.00 86.64 ? 531 LEU C O 1 ATOM 3673 C CB . LEU A 1 466 ? -159.464 -134.744 208.516 1.00 82.08 ? 531 LEU C CB 1 ATOM 3674 C CG . LEU A 1 466 ? -158.911 -136.165 208.519 1.00 81.40 ? 531 LEU C CG 1 ATOM 3675 C CD1 . LEU A 1 466 ? -160.046 -137.179 208.560 1.00 80.64 ? 531 LEU C CD1 1 ATOM 3676 C CD2 . LEU A 1 466 ? -158.062 -136.380 207.294 1.00 75.52 ? 531 LEU C CD2 1 ATOM 3677 N N . LEU A 1 467 ? -159.560 -131.749 209.616 1.00 88.43 ? 532 LEU C N 1 ATOM 3678 C CA . LEU A 1 467 ? -160.226 -130.460 209.645 1.00 89.78 ? 532 LEU C CA 1 ATOM 3679 C C . LEU A 1 467 ? -159.256 -129.347 209.269 1.00 91.02 ? 532 LEU C C 1 ATOM 3680 O O . LEU A 1 467 ? -159.591 -128.419 208.528 1.00 89.64 ? 532 LEU C O 1 ATOM 3681 C CB . LEU A 1 467 ? -160.794 -130.209 211.029 1.00 90.99 ? 532 LEU C CB 1 ATOM 3682 C CG . LEU A 1 467 ? -161.775 -129.059 211.083 1.00 91.08 ? 532 LEU C CG 1 ATOM 3683 C CD1 . LEU A 1 467 ? -162.994 -129.430 210.264 1.00 88.47 ? 532 LEU C CD1 1 ATOM 3684 C CD2 . LEU A 1 467 ? -162.133 -128.794 212.523 1.00 92.32 ? 532 LEU C CD2 1 ATOM 3685 N N . PHE A 1 468 ? -158.031 -129.486 209.763 1.00 92.18 ? 533 PHE C N 1 ATOM 3686 C CA . PHE A 1 468 ? -156.967 -128.512 209.546 1.00 89.20 ? 533 PHE C CA 1 ATOM 3687 C C . PHE A 1 468 ? -156.615 -128.385 208.071 1.00 92.21 ? 533 PHE C C 1 ATOM 3688 O O . PHE A 1 468 ? -156.373 -127.292 207.574 1.00 93.51 ? 533 PHE C O 1 ATOM 3689 C CB . PHE A 1 468 ? -155.739 -128.936 210.351 1.00 84.37 ? 533 PHE C CB 1 ATOM 3690 C CG . PHE A 1 468 ? -154.511 -128.124 210.086 1.00 92.85 ? 533 PHE C CG 1 ATOM 3691 C CD1 . PHE A 1 468 ? -154.330 -126.896 210.700 1.00 97.80 ? 533 PHE C CD1 1 ATOM 3692 C CD2 . PHE A 1 468 ? -153.506 -128.613 209.269 1.00 92.03 ? 533 PHE C CD2 1 ATOM 3693 C CE1 . PHE A 1 468 ? -153.182 -126.157 210.480 1.00 95.98 ? 533 PHE C CE1 1 ATOM 3694 C CE2 . PHE A 1 468 ? -152.355 -127.879 209.043 1.00 90.20 ? 533 PHE C CE2 1 ATOM 3695 C CZ . PHE A 1 468 ? -152.195 -126.649 209.647 1.00 90.84 ? 533 PHE C CZ 1 ATOM 3696 N N . ILE A 1 469 ? -156.623 -129.516 207.374 1.00 91.46 ? 534 ILE C N 1 ATOM 3697 C CA . ILE A 1 469 ? -156.347 -129.558 205.947 1.00 83.71 ? 534 ILE C CA 1 ATOM 3698 C C . ILE A 1 469 ? -157.508 -128.972 205.161 1.00 86.35 ? 534 ILE C C 1 ATOM 3699 O O . ILE A 1 469 ? -157.311 -128.154 204.278 1.00 91.39 ? 534 ILE C O 1 ATOM 3700 C CB . ILE A 1 469 ? -156.099 -131.007 205.477 1.00 82.38 ? 534 ILE C CB 1 ATOM 3701 C CG1 . ILE A 1 469 ? -154.891 -131.590 206.182 1.00 75.25 ? 534 ILE C CG1 1 ATOM 3702 C CG2 . ILE A 1 469 ? -155.926 -131.083 203.972 1.00 78.77 ? 534 ILE C CG2 1 ATOM 3703 C CD1 . ILE A 1 469 ? -154.765 -133.056 205.980 1.00 80.68 ? 534 ILE C CD1 1 ATOM 3704 N N . THR A 1 470 ? -158.721 -129.389 205.505 1.00 87.92 ? 535 THR C N 1 ATOM 3705 C CA . THR A 1 470 ? -159.901 -128.990 204.755 1.00 86.44 ? 535 THR C CA 1 ATOM 3706 C C . THR A 1 470 ? -160.161 -127.496 204.835 1.00 91.93 ? 535 THR C C 1 ATOM 3707 O O . THR A 1 470 ? -160.604 -126.889 203.863 1.00 96.74 ? 535 THR C O 1 ATOM 3708 C CB . THR A 1 470 ? -161.153 -129.734 205.237 1.00 86.62 ? 535 THR C CB 1 ATOM 3709 O OG1 . THR A 1 470 ? -160.992 -131.139 205.014 1.00 88.31 ? 535 THR C OG1 1 ATOM 3710 C CG2 . THR A 1 470 ? -162.383 -129.248 204.487 1.00 86.64 ? 535 THR C CG2 1 ATOM 3711 N N . VAL A 1 471 ? -159.871 -126.895 205.983 1.00 91.16 ? 536 VAL C N 1 ATOM 3712 C CA . VAL A 1 471 ? -160.157 -125.481 206.164 1.00 90.00 ? 536 VAL C CA 1 ATOM 3713 C C . VAL A 1 471 ? -159.173 -124.613 205.402 1.00 87.58 ? 536 VAL C C 1 ATOM 3714 O O . VAL A 1 471 ? -159.576 -123.666 204.743 1.00 95.57 ? 536 VAL C O 1 ATOM 3715 C CB . VAL A 1 471 ? -160.154 -125.097 207.660 1.00 95.11 ? 536 VAL C CB 1 ATOM 3716 C CG1 . VAL A 1 471 ? -160.025 -123.596 207.822 1.00 92.67 ? 536 VAL C CG1 1 ATOM 3717 C CG2 . VAL A 1 471 ? -161.426 -125.606 208.336 1.00 86.96 ? 536 VAL C CG2 1 ATOM 3718 N N . TYR A 1 472 ? -157.888 -124.929 205.480 1.00 89.62 ? 537 TYR C N 1 ATOM 3719 C CA . TYR A 1 472 ? -156.892 -124.183 204.709 1.00 93.68 ? 537 TYR C CA 1 ATOM 3720 C C . TYR A 1 472 ? -157.000 -124.456 203.216 1.00 96.92 ? 537 TYR C C 1 ATOM 3721 O O . TYR A 1 472 ? -156.570 -123.651 202.397 1.00 99.98 ? 537 TYR C O 1 ATOM 3722 C CB . TYR A 1 472 ? -155.477 -124.499 205.181 1.00 89.44 ? 537 TYR C CB 1 ATOM 3723 C CG . TYR A 1 472 ? -155.142 -123.836 206.491 1.00 97.78 ? 537 TYR C CG 1 ATOM 3724 C CD1 . TYR A 1 472 ? -154.830 -122.482 206.545 1.00 94.63 ? 537 TYR C CD1 1 ATOM 3725 C CD2 . TYR A 1 472 ? -155.148 -124.559 207.681 1.00 100.28 ? 537 TYR C CD2 1 ATOM 3726 C CE1 . TYR A 1 472 ? -154.523 -121.867 207.744 1.00 95.46 ? 537 TYR C CE1 1 ATOM 3727 C CE2 . TYR A 1 472 ? -154.848 -123.950 208.886 1.00 104.37 ? 537 TYR C CE2 1 ATOM 3728 C CZ . TYR A 1 472 ? -154.536 -122.598 208.908 1.00 102.95 ? 537 TYR C CZ 1 ATOM 3729 O OH . TYR A 1 472 ? -154.228 -121.970 210.091 1.00 113.71 ? 537 TYR C OH 1 ATOM 3730 N N . GLY A 1 473 ? -157.570 -125.597 202.858 1.00 93.05 ? 538 GLY C N 1 ATOM 3731 C CA . GLY A 1 473 ? -157.818 -125.882 201.462 1.00 95.99 ? 538 GLY C CA 1 ATOM 3732 C C . GLY A 1 473 ? -159.038 -125.140 200.942 1.00 100.91 ? 538 GLY C C 1 ATOM 3733 O O . GLY A 1 473 ? -159.253 -125.061 199.731 1.00 104.52 ? 538 GLY C O 1 ATOM 3734 N N . LEU A 1 474 ? -159.842 -124.599 201.854 1.00 100.61 ? 539 LEU C N 1 ATOM 3735 C CA . LEU A 1 474 ? -160.990 -123.788 201.469 1.00 101.64 ? 539 LEU C CA 1 ATOM 3736 C C . LEU A 1 474 ? -160.567 -122.334 201.384 1.00 101.46 ? 539 LEU C C 1 ATOM 3737 O O . LEU A 1 474 ? -160.818 -121.660 200.386 1.00 103.41 ? 539 LEU C O 1 ATOM 3738 C CB . LEU A 1 474 ? -162.150 -123.949 202.462 1.00 99.64 ? 539 LEU C CB 1 ATOM 3739 C CG . LEU A 1 474 ? -162.942 -125.266 202.423 1.00 101.73 ? 539 LEU C CG 1 ATOM 3740 C CD1 . LEU A 1 474 ? -164.056 -125.280 203.473 1.00 101.65 ? 539 LEU C CD1 1 ATOM 3741 C CD2 . LEU A 1 474 ? -163.506 -125.543 201.032 1.00 95.83 ? 539 LEU C CD2 1 ATOM 3742 N N . ILE A 1 475 ? -159.898 -121.864 202.431 1.00 103.07 ? 540 ILE C N 1 ATOM 3743 C CA . ILE A 1 475 ? -159.489 -120.464 202.518 1.00 104.98 ? 540 ILE C CA 1 ATOM 3744 C C . ILE A 1 475 ? -158.504 -120.109 201.408 1.00 102.37 ? 540 ILE C C 1 ATOM 3745 O O . ILE A 1 475 ? -158.383 -118.951 201.015 1.00 109.78 ? 540 ILE C O 1 ATOM 3746 C CB . ILE A 1 475 ? -158.864 -120.143 203.892 1.00 99.96 ? 540 ILE C CB 1 ATOM 3747 C CG1 . ILE A 1 475 ? -158.769 -118.632 204.089 1.00 112.25 ? 540 ILE C CG1 1 ATOM 3748 C CG2 . ILE A 1 475 ? -157.504 -120.792 204.032 1.00 103.00 ? 540 ILE C CG2 1 ATOM 3749 C CD1 . ILE A 1 475 ? -158.420 -118.226 205.499 1.00 121.04 ? 540 ILE C CD1 1 ATOM 3750 N N . GLY A 1 476 ? -157.797 -121.115 200.913 1.00 104.33 ? 541 GLY C N 1 ATOM 3751 C CA . GLY A 1 476 ? -156.894 -120.928 199.797 1.00 103.20 ? 541 GLY C CA 1 ATOM 3752 C C . GLY A 1 476 ? -157.536 -121.119 198.434 1.00 103.32 ? 541 GLY C C 1 ATOM 3753 O O . GLY A 1 476 ? -156.845 -121.039 197.415 1.00 107.40 ? 541 GLY C O 1 ATOM 3754 N N . TYR A 1 477 ? -158.844 -121.370 198.396 1.00 100.56 ? 542 TYR C N 1 ATOM 3755 C CA . TYR A 1 477 ? -159.510 -121.675 197.127 1.00 100.77 ? 542 TYR C CA 1 ATOM 3756 C C . TYR A 1 477 ? -159.466 -120.527 196.122 1.00 102.99 ? 542 TYR C C 1 ATOM 3757 O O . TYR A 1 477 ? -159.572 -119.352 196.483 1.00 106.59 ? 542 TYR C O 1 ATOM 3758 C CB . TYR A 1 477 ? -160.966 -122.057 197.353 1.00 96.56 ? 542 TYR C CB 1 ATOM 3759 C CG . TYR A 1 477 ? -161.731 -122.296 196.072 1.00 92.98 ? 542 TYR C CG 1 ATOM 3760 C CD1 . TYR A 1 477 ? -161.757 -123.548 195.485 1.00 96.90 ? 542 TYR C CD1 1 ATOM 3761 C CD2 . TYR A 1 477 ? -162.426 -121.269 195.450 1.00 96.26 ? 542 TYR C CD2 1 ATOM 3762 C CE1 . TYR A 1 477 ? -162.453 -123.778 194.309 1.00 100.07 ? 542 TYR C CE1 1 ATOM 3763 C CE2 . TYR A 1 477 ? -163.125 -121.483 194.269 1.00 97.27 ? 542 TYR C CE2 1 ATOM 3764 C CZ . TYR A 1 477 ? -163.137 -122.741 193.705 1.00 98.33 ? 542 TYR C CZ 1 ATOM 3765 O OH . TYR A 1 477 ? -163.824 -122.970 192.537 1.00 95.05 ? 542 TYR C OH 1 ATOM 3766 N N . GLU A 1 478 ? -159.287 -120.886 194.854 1.00 102.51 ? 543 GLU C N 1 ATOM 3767 C CA . GLU A 1 478 ? -159.378 -119.955 193.728 1.00 101.06 ? 543 GLU C CA 1 ATOM 3768 C C . GLU A 1 478 ? -160.028 -120.687 192.563 1.00 97.79 ? 543 GLU C C 1 ATOM 3769 O O . GLU A 1 478 ? -159.928 -121.903 192.476 1.00 102.88 ? 543 GLU C O 1 ATOM 3770 C CB . GLU A 1 478 ? -158.001 -119.433 193.332 1.00 103.92 ? 543 GLU C CB 1 ATOM 3771 C CG . GLU A 1 478 ? -157.204 -118.850 194.492 1.00 108.72 ? 543 GLU C CG 1 ATOM 3772 C CD . GLU A 1 478 ? -155.833 -118.360 194.076 1.00 118.55 ? 543 GLU C CD 1 ATOM 3773 O OE1 . GLU A 1 478 ? -155.282 -118.895 193.090 1.00 120.76 ? 543 GLU C OE1 1 ATOM 3774 O OE2 . GLU A 1 478 ? -155.310 -117.432 194.731 1.00 124.75 ? 543 GLU C OE2 1 ATOM 3775 N N . PRO A 1 479 ? -160.697 -119.961 191.666 1.00 97.81 ? 544 PRO C N 1 ATOM 3776 C CA . PRO A 1 479 ? -161.316 -120.656 190.533 1.00 96.03 ? 544 PRO C CA 1 ATOM 3777 C C . PRO A 1 479 ? -160.271 -121.351 189.670 1.00 94.34 ? 544 PRO C C 1 ATOM 3778 O O . PRO A 1 479 ? -159.127 -120.904 189.594 1.00 94.07 ? 544 PRO C O 1 ATOM 3779 C CB . PRO A 1 479 ? -162.016 -119.529 189.767 1.00 99.22 ? 544 PRO C CB 1 ATOM 3780 C CG . PRO A 1 479 ? -162.268 -118.492 190.799 1.00 97.47 ? 544 PRO C CG 1 ATOM 3781 C CD . PRO A 1 479 ? -161.096 -118.547 191.733 1.00 100.82 ? 544 PRO C CD 1 ATOM 3782 N N . LEU A 1 480 ? -160.661 -122.481 189.095 1.00 93.53 ? 545 LEU C N 1 ATOM 3783 C CA . LEU A 1 480 ? -159.729 -123.338 188.384 1.00 90.18 ? 545 LEU C CA 1 ATOM 3784 C C . LEU A 1 480 ? -159.135 -122.638 187.181 1.00 88.88 ? 545 LEU C C 1 ATOM 3785 O O . LEU A 1 480 ? -159.844 -121.961 186.429 1.00 87.76 ? 545 LEU C O 1 ATOM 3786 C CB . LEU A 1 480 ? -160.405 -124.631 187.938 1.00 85.93 ? 545 LEU C CB 1 ATOM 3787 C CG . LEU A 1 480 ? -159.467 -125.624 187.253 1.00 80.97 ? 545 LEU C CG 1 ATOM 3788 C CD1 . LEU A 1 480 ? -158.300 -125.983 188.164 1.00 81.32 ? 545 LEU C CD1 1 ATOM 3789 C CD2 . LEU A 1 480 ? -160.226 -126.860 186.844 1.00 81.10 ? 545 LEU C CD2 1 ATOM 3790 N N . THR A 1 481 ? -157.832 -122.838 186.997 1.00 85.80 ? 546 THR C N 1 ATOM 3791 C CA . THR A 1 481 ? -157.096 -122.288 185.870 1.00 83.33 ? 546 THR C CA 1 ATOM 3792 C C . THR A 1 481 ? -155.947 -123.217 185.534 1.00 79.75 ? 546 THR C C 1 ATOM 3793 O O . THR A 1 481 ? -155.498 -123.978 186.391 1.00 88.33 ? 546 THR C O 1 ATOM 3794 C CB . THR A 1 481 ? -156.531 -120.888 186.179 1.00 84.07 ? 546 THR C CB 1 ATOM 3795 O OG1 . THR A 1 481 ? -155.507 -120.998 187.177 1.00 80.07 ? 546 THR C OG1 1 ATOM 3796 C CG2 . THR A 1 481 ? -157.621 -119.957 186.676 1.00 78.45 ? 546 THR C CG2 1 ATOM 3797 N N . TYR A 1 482 ? -155.477 -123.171 184.293 1.00 75.60 ? 547 TYR C N 1 ATOM 3798 C CA . TYR A 1 482 ? -154.229 -123.840 183.950 1.00 78.44 ? 547 TYR C CA 1 ATOM 3799 C C . TYR A 1 482 ? -153.458 -122.980 182.975 1.00 78.96 ? 547 TYR C C 1 ATOM 3800 O O . TYR A 1 482 ? -154.016 -122.545 181.967 1.00 78.59 ? 547 TYR C O 1 ATOM 3801 C CB . TYR A 1 482 ? -154.458 -125.226 183.346 1.00 77.78 ? 547 TYR C CB 1 ATOM 3802 C CG . TYR A 1 482 ? -153.145 -125.892 183.002 1.00 76.93 ? 547 TYR C CG 1 ATOM 3803 C CD1 . TYR A 1 482 ? -152.294 -126.329 184.003 1.00 77.87 ? 547 TYR C CD1 1 ATOM 3804 C CD2 . TYR A 1 482 ? -152.742 -126.051 181.689 1.00 75.45 ? 547 TYR C CD2 1 ATOM 3805 C CE1 . TYR A 1 482 ? -151.080 -126.917 183.709 1.00 76.92 ? 547 TYR C CE1 1 ATOM 3806 C CE2 . TYR A 1 482 ? -151.530 -126.648 181.380 1.00 75.17 ? 547 TYR C CE2 1 ATOM 3807 C CZ . TYR A 1 482 ? -150.700 -127.074 182.391 1.00 77.88 ? 547 TYR C CZ 1 ATOM 3808 O OH . TYR A 1 482 ? -149.493 -127.664 182.075 1.00 81.39 ? 547 TYR C OH 1 ATOM 3809 N N . ALA A 1 483 ? -152.172 -122.772 183.263 1.00 78.50 ? 548 ALA C N 1 ATOM 3810 C CA . ALA A 1 483 ? -151.359 -121.766 182.573 1.00 76.96 ? 548 ALA C CA 1 ATOM 3811 C C . ALA A 1 483 ? -152.173 -120.493 182.391 1.00 79.64 ? 548 ALA C C 1 ATOM 3812 O O . ALA A 1 483 ? -152.718 -119.966 183.368 1.00 81.14 ? 548 ALA C O 1 ATOM 3813 C CB . ALA A 1 483 ? -150.847 -122.286 181.234 1.00 77.53 ? 548 ALA C CB 1 ATOM 3814 N N . ASP A 1 484 ? -152.269 -120.001 181.157 1.00 73.72 ? 549 ASP C N 1 ATOM 3815 C CA . ASP A 1 484 ? -152.956 -118.735 180.922 1.00 77.29 ? 549 ASP C CA 1 ATOM 3816 C C . ASP A 1 484 ? -154.470 -118.876 180.773 1.00 77.56 ? 549 ASP C C 1 ATOM 3817 O O . ASP A 1 484 ? -155.187 -117.876 180.770 1.00 89.04 ? 549 ASP C O 1 ATOM 3818 C CB . ASP A 1 484 ? -152.370 -118.035 179.687 1.00 81.62 ? 549 ASP C CB 1 ATOM 3819 C CG . ASP A 1 484 ? -152.418 -116.498 179.792 1.00 82.13 ? 549 ASP C CG 1 ATOM 3820 O OD1 . ASP A 1 484 ? -152.585 -115.959 180.914 1.00 73.47 ? 549 ASP C OD1 1 ATOM 3821 O OD2 . ASP A 1 484 ? -152.273 -115.833 178.741 1.00 83.09 ? 549 ASP C OD2 1 ATOM 3822 N N . TYR A 1 485 ? -154.948 -120.105 180.610 1.00 78.68 ? 550 TYR C N 1 ATOM 3823 C CA . TYR A 1 485 ? -156.388 -120.386 180.499 1.00 80.37 ? 550 TYR C CA 1 ATOM 3824 C C . TYR A 1 485 ? -157.120 -120.255 181.839 1.00 85.70 ? 550 TYR C C 1 ATOM 3825 O O . TYR A 1 485 ? -156.607 -120.697 182.874 1.00 84.29 ? 550 TYR C O 1 ATOM 3826 C CB . TYR A 1 485 ? -156.597 -121.788 179.925 1.00 76.21 ? 550 TYR C CB 1 ATOM 3827 C CG . TYR A 1 485 ? -158.026 -122.259 179.797 1.00 81.16 ? 550 TYR C CG 1 ATOM 3828 C CD1 . TYR A 1 485 ? -158.851 -121.797 178.779 1.00 78.55 ? 550 TYR C CD1 1 ATOM 3829 C CD2 . TYR A 1 485 ? -158.542 -123.208 180.674 1.00 87.32 ? 550 TYR C CD2 1 ATOM 3830 C CE1 . TYR A 1 485 ? -160.160 -122.252 178.654 1.00 84.21 ? 550 TYR C CE1 1 ATOM 3831 C CE2 . TYR A 1 485 ? -159.857 -123.663 180.562 1.00 86.55 ? 550 TYR C CE2 1 ATOM 3832 C CZ . TYR A 1 485 ? -160.658 -123.184 179.547 1.00 85.95 ? 550 TYR C CZ 1 ATOM 3833 O OH . TYR A 1 485 ? -161.959 -123.626 179.422 1.00 87.45 ? 550 TYR C OH 1 ATOM 3834 N N . VAL A 1 486 ? -158.323 -119.678 181.825 1.00 86.09 ? 551 VAL C N 1 ATOM 3835 C CA . VAL A 1 486 ? -159.191 -119.725 183.002 1.00 87.24 ? 551 VAL C CA 1 ATOM 3836 C C . VAL A 1 486 ? -160.460 -120.461 182.651 1.00 86.25 ? 551 VAL C C 1 ATOM 3837 O O . VAL A 1 486 ? -161.116 -120.164 181.662 1.00 88.57 ? 551 VAL C O 1 ATOM 3838 C CB . VAL A 1 486 ? -159.563 -118.322 183.568 1.00 82.40 ? 551 VAL C CB 1 ATOM 3839 C CG1 . VAL A 1 486 ? -158.313 -117.549 183.932 1.00 81.11 ? 551 VAL C CG1 1 ATOM 3840 C CG2 . VAL A 1 486 ? -160.413 -117.551 182.595 1.00 92.41 ? 551 VAL C CG2 1 ATOM 3841 N N . TYR A 1 487 ? -160.799 -121.435 183.478 1.00 92.52 ? 552 TYR C N 1 ATOM 3842 C CA . TYR A 1 487 ? -161.981 -122.241 183.242 1.00 93.64 ? 552 TYR C CA 1 ATOM 3843 C C . TYR A 1 487 ? -163.241 -121.401 183.391 1.00 92.15 ? 552 TYR C C 1 ATOM 3844 O O . TYR A 1 487 ? -163.325 -120.551 184.279 1.00 93.91 ? 552 TYR C O 1 ATOM 3845 C CB . TYR A 1 487 ? -162.013 -123.435 184.204 1.00 90.85 ? 552 TYR C CB 1 ATOM 3846 C CG . TYR A 1 487 ? -161.059 -124.545 183.826 1.00 85.74 ? 552 TYR C CG 1 ATOM 3847 C CD1 . TYR A 1 487 ? -161.504 -125.648 183.114 1.00 84.58 ? 552 TYR C CD1 1 ATOM 3848 C CD2 . TYR A 1 487 ? -159.716 -124.481 184.162 1.00 81.80 ? 552 TYR C CD2 1 ATOM 3849 C CE1 . TYR A 1 487 ? -160.642 -126.662 182.757 1.00 81.66 ? 552 TYR C CE1 1 ATOM 3850 C CE2 . TYR A 1 487 ? -158.852 -125.491 183.810 1.00 79.18 ? 552 TYR C CE2 1 ATOM 3851 C CZ . TYR A 1 487 ? -159.319 -126.578 183.115 1.00 76.38 ? 552 TYR C CZ 1 ATOM 3852 O OH . TYR A 1 487 ? -158.453 -127.582 182.768 1.00 75.78 ? 552 TYR C OH 1 ATOM 3853 N N . PRO A 1 488 ? -164.228 -121.658 182.522 1.00 90.06 ? 553 PRO C N 1 ATOM 3854 C CA . PRO A 1 488 ? -165.570 -121.066 182.540 1.00 92.32 ? 553 PRO C CA 1 ATOM 3855 C C . PRO A 1 488 ? -166.316 -121.427 183.817 1.00 95.62 ? 553 PRO C C 1 ATOM 3856 O O . PRO A 1 488 ? -166.055 -122.475 184.399 1.00 100.27 ? 553 PRO C O 1 ATOM 3857 C CB . PRO A 1 488 ? -166.249 -121.692 181.318 1.00 92.10 ? 553 PRO C CB 1 ATOM 3858 C CG . PRO A 1 488 ? -165.458 -122.917 181.017 1.00 93.55 ? 553 PRO C CG 1 ATOM 3859 C CD . PRO A 1 488 ? -164.050 -122.575 181.385 1.00 89.34 ? 553 PRO C CD 1 ATOM 3860 N N . SER A 1 489 ? -167.188 -120.537 184.280 1.00 100.24 ? 554 SER C N 1 ATOM 3861 C CA . SER A 1 489 ? -167.871 -120.750 185.551 1.00 96.01 ? 554 SER C CA 1 ATOM 3862 C C . SER A 1 489 ? -168.679 -122.046 185.575 1.00 93.71 ? 554 SER C C 1 ATOM 3863 O O . SER A 1 489 ? -168.804 -122.679 186.619 1.00 95.96 ? 554 SER C O 1 ATOM 3864 C CB . SER A 1 489 ? -168.783 -119.562 185.862 1.00 94.63 ? 554 SER C CB 1 ATOM 3865 O OG . SER A 1 489 ? -168.026 -118.369 186.007 1.00 105.33 ? 554 SER C OG 1 ATOM 3866 N N . TRP A 1 490 ? -169.227 -122.452 184.436 1.00 92.06 ? 555 TRP C N 1 ATOM 3867 C CA . TRP A 1 490 ? -169.972 -123.707 184.393 1.00 94.10 ? 555 TRP C CA 1 ATOM 3868 C C . TRP A 1 490 ? -169.076 -124.920 184.614 1.00 97.18 ? 555 TRP C C 1 ATOM 3869 O O . TRP A 1 490 ? -169.491 -125.912 185.219 1.00 96.83 ? 555 TRP C O 1 ATOM 3870 C CB . TRP A 1 490 ? -170.701 -123.852 183.059 1.00 94.39 ? 555 TRP C CB 1 ATOM 3871 C CG . TRP A 1 490 ? -169.790 -123.861 181.878 1.00 97.42 ? 555 TRP C CG 1 ATOM 3872 C CD1 . TRP A 1 490 ? -169.465 -122.798 181.085 1.00 101.06 ? 555 TRP C CD1 1 ATOM 3873 C CD2 . TRP A 1 490 ? -169.085 -124.992 181.346 1.00 100.96 ? 555 TRP C CD2 1 ATOM 3874 N NE1 . TRP A 1 490 ? -168.597 -123.198 180.084 1.00 103.75 ? 555 TRP C NE1 1 ATOM 3875 C CE2 . TRP A 1 490 ? -168.349 -124.538 180.226 1.00 99.50 ? 555 TRP C CE2 1 ATOM 3876 C CE3 . TRP A 1 490 ? -168.998 -126.342 181.711 1.00 99.43 ? 555 TRP C CE3 1 ATOM 3877 C CZ2 . TRP A 1 490 ? -167.545 -125.384 179.473 1.00 94.98 ? 555 TRP C CZ2 1 ATOM 3878 C CZ3 . TRP A 1 490 ? -168.189 -127.184 180.956 1.00 96.22 ? 555 TRP C CZ3 1 ATOM 3879 C CH2 . TRP A 1 490 ? -167.476 -126.699 179.852 1.00 94.47 ? 555 TRP C CH2 1 ATOM 3880 N N . ALA A 1 491 ? -167.840 -124.836 184.127 1.00 97.53 ? 556 ALA C N 1 ATOM 3881 C CA . ALA A 1 491 ? -166.889 -125.925 184.303 1.00 93.94 ? 556 ALA C CA 1 ATOM 3882 C C . ALA A 1 491 ? -166.566 -126.056 185.773 1.00 91.41 ? 556 ALA C C 1 ATOM 3883 O O . ALA A 1 491 ? -166.484 -127.162 186.302 1.00 92.77 ? 556 ALA C O 1 ATOM 3884 C CB . ALA A 1 491 ? -165.626 -125.678 183.502 1.00 91.08 ? 556 ALA C CB 1 ATOM 3885 N N . ASN A 1 492 ? -166.433 -124.913 186.435 1.00 90.05 ? 557 ASN C N 1 ATOM 3886 C CA . ASN A 1 492 ? -166.178 -124.885 187.863 1.00 94.17 ? 557 ASN C CA 1 ATOM 3887 C C . ASN A 1 492 ? -167.297 -125.557 188.650 1.00 95.19 ? 557 ASN C C 1 ATOM 3888 O O . ASN A 1 492 ? -167.043 -126.407 189.503 1.00 98.01 ? 557 ASN C O 1 ATOM 3889 C CB . ASN A 1 492 ? -166.013 -123.447 188.346 1.00 89.63 ? 557 ASN C CB 1 ATOM 3890 C CG . ASN A 1 492 ? -164.588 -122.975 188.288 1.00 93.19 ? 557 ASN C CG 1 ATOM 3891 O OD1 . ASN A 1 492 ? -163.740 -123.448 189.043 1.00 92.96 ? 557 ASN C OD1 1 ATOM 3892 N ND2 . ASN A 1 492 ? -164.310 -122.025 187.403 1.00 98.45 ? 557 ASN C ND2 1 ATOM 3893 N N . ALA A 1 493 ? -168.535 -125.168 188.364 1.00 96.05 ? 558 ALA C N 1 ATOM 3894 C CA . ALA A 1 493 ? -169.683 -125.722 189.065 1.00 95.84 ? 558 ALA C CA 1 ATOM 3895 C C . ALA A 1 493 ? -169.842 -127.212 188.768 1.00 94.67 ? 558 ALA C C 1 ATOM 3896 O O . ALA A 1 493 ? -170.251 -127.984 189.634 1.00 95.95 ? 558 ALA C O 1 ATOM 3897 C CB . ALA A 1 493 ? -170.948 -124.954 188.687 1.00 92.69 ? 558 ALA C CB 1 ATOM 3898 N N . LEU A 1 494 ? -169.491 -127.616 187.553 1.00 91.50 ? 559 LEU C N 1 ATOM 3899 C CA . LEU A 1 494 ? -169.583 -129.020 187.176 1.00 91.24 ? 559 LEU C CA 1 ATOM 3900 C C . LEU A 1 494 ? -168.630 -129.891 188.000 1.00 93.74 ? 559 LEU C C 1 ATOM 3901 O O . LEU A 1 494 ? -168.906 -131.055 188.273 1.00 92.00 ? 559 LEU C O 1 ATOM 3902 C CB . LEU A 1 494 ? -169.282 -129.182 185.693 1.00 90.56 ? 559 LEU C CB 1 ATOM 3903 C CG . LEU A 1 494 ? -169.083 -130.625 185.259 1.00 87.82 ? 559 LEU C CG 1 ATOM 3904 C CD1 . LEU A 1 494 ? -170.357 -131.395 185.484 1.00 88.77 ? 559 LEU C CD1 1 ATOM 3905 C CD2 . LEU A 1 494 ? -168.675 -130.668 183.801 1.00 99.01 ? 559 LEU C CD2 1 ATOM 3906 N N . GLY A 1 495 ? -167.496 -129.325 188.384 1.00 94.06 ? 560 GLY C N 1 ATOM 3907 C CA . GLY A 1 495 ? -166.549 -130.057 189.196 1.00 92.33 ? 560 GLY C CA 1 ATOM 3908 C C . GLY A 1 495 ? -167.011 -130.076 190.636 1.00 93.96 ? 560 GLY C C 1 ATOM 3909 O O . GLY A 1 495 ? -166.724 -131.012 191.387 1.00 95.54 ? 560 GLY C O 1 ATOM 3910 N N . TRP A 1 496 ? -167.735 -129.034 191.026 1.00 92.75 ? 561 TRP C N 1 ATOM 3911 C CA . TRP A 1 496 ? -168.352 -129.013 192.337 1.00 89.28 ? 561 TRP C CA 1 ATOM 3912 C C . TRP A 1 496 ? -169.408 -130.101 192.424 1.00 86.92 ? 561 TRP C C 1 ATOM 3913 O O . TRP A 1 496 ? -169.693 -130.613 193.500 1.00 84.80 ? 561 TRP C O 1 ATOM 3914 C CB . TRP A 1 496 ? -168.953 -127.648 192.631 1.00 86.92 ? 561 TRP C CB 1 ATOM 3915 C CG . TRP A 1 496 ? -167.941 -126.644 192.999 1.00 90.30 ? 561 TRP C CG 1 ATOM 3916 C CD1 . TRP A 1 496 ? -167.628 -125.499 192.317 1.00 96.20 ? 561 TRP C CD1 1 ATOM 3917 C CD2 . TRP A 1 496 ? -167.082 -126.683 194.141 1.00 97.64 ? 561 TRP C CD2 1 ATOM 3918 N NE1 . TRP A 1 496 ? -166.627 -124.817 192.973 1.00 97.86 ? 561 TRP C NE1 1 ATOM 3919 C CE2 . TRP A 1 496 ? -166.274 -125.525 194.094 1.00 99.89 ? 561 TRP C CE2 1 ATOM 3920 C CE3 . TRP A 1 496 ? -166.915 -127.584 195.205 1.00 96.28 ? 561 TRP C CE3 1 ATOM 3921 C CZ2 . TRP A 1 496 ? -165.316 -125.248 195.069 1.00 104.65 ? 561 TRP C CZ2 1 ATOM 3922 C CZ3 . TRP A 1 496 ? -165.960 -127.306 196.170 1.00 92.60 ? 561 TRP C CZ3 1 ATOM 3923 C CH2 . TRP A 1 496 ? -165.177 -126.148 196.098 1.00 100.75 ? 561 TRP C CH2 1 ATOM 3924 N N . CYS A 1 497 ? -169.989 -130.450 191.285 1.00 84.13 ? 562 CYS C N 1 ATOM 3925 C CA . CYS A 1 497 ? -170.961 -131.524 191.266 1.00 90.25 ? 562 CYS C CA 1 ATOM 3926 C C . CYS A 1 497 ? -170.273 -132.844 191.531 1.00 88.88 ? 562 CYS C C 1 ATOM 3927 O O . CYS A 1 497 ? -170.700 -133.621 192.382 1.00 88.42 ? 562 CYS C O 1 ATOM 3928 C CB . CYS A 1 497 ? -171.704 -131.565 189.930 1.00 97.02 ? 562 CYS C CB 1 ATOM 3929 S SG . CYS A 1 497 ? -173.009 -130.344 189.827 1.00 105.13 ? 562 CYS C SG 1 ATOM 3930 N N . ILE A 1 498 ? -169.176 -133.073 190.823 1.00 89.85 ? 563 ILE C N 1 ATOM 3931 C CA . ILE A 1 498 ? -168.423 -134.300 190.990 1.00 88.24 ? 563 ILE C CA 1 ATOM 3932 C C . ILE A 1 498 ? -167.931 -134.395 192.423 1.00 86.34 ? 563 ILE C C 1 ATOM 3933 O O . ILE A 1 498 ? -167.870 -135.479 193.001 1.00 91.12 ? 563 ILE C O 1 ATOM 3934 C CB . ILE A 1 498 ? -167.231 -134.346 190.037 1.00 85.38 ? 563 ILE C CB 1 ATOM 3935 C CG1 . ILE A 1 498 ? -167.693 -134.043 188.613 1.00 84.77 ? 563 ILE C CG1 1 ATOM 3936 C CG2 . ILE A 1 498 ? -166.532 -135.690 190.125 1.00 83.24 ? 563 ILE C CG2 1 ATOM 3937 C CD1 . ILE A 1 498 ? -166.643 -134.332 187.572 1.00 79.95 ? 563 ILE C CD1 1 ATOM 3938 N N . ALA A 1 499 ? -167.609 -133.244 193.001 1.00 80.40 ? 564 ALA C N 1 ATOM 3939 C CA . ALA A 1 499 ? -167.052 -133.202 194.343 1.00 85.46 ? 564 ALA C CA 1 ATOM 3940 C C . ALA A 1 499 ? -168.103 -133.562 195.377 1.00 88.43 ? 564 ALA C C 1 ATOM 3941 O O . ALA A 1 499 ? -167.873 -134.411 196.250 1.00 86.91 ? 564 ALA C O 1 ATOM 3942 C CB . ALA A 1 499 ? -166.478 -131.825 194.633 1.00 84.06 ? 564 ALA C CB 1 ATOM 3943 N N . GLY A 1 500 ? -169.261 -132.917 195.264 1.00 90.41 ? 565 GLY C N 1 ATOM 3944 C CA . GLY A 1 500 ? -170.361 -133.147 196.183 1.00 87.41 ? 565 GLY C CA 1 ATOM 3945 C C . GLY A 1 500 ? -171.208 -134.357 195.840 1.00 83.72 ? 565 GLY C C 1 ATOM 3946 O O . GLY A 1 500 ? -171.986 -134.819 196.666 1.00 84.06 ? 565 GLY C O 1 ATOM 3947 N N . SER A 1 501 ? -171.042 -134.896 194.636 1.00 84.25 ? 566 SER C N 1 ATOM 3948 C CA . SER A 1 501 ? -171.875 -136.015 194.212 1.00 79.31 ? 566 SER C CA 1 ATOM 3949 C C . SER A 1 501 ? -171.641 -137.203 195.137 1.00 85.28 ? 566 SER C C 1 ATOM 3950 O O . SER A 1 501 ? -172.540 -138.002 195.379 1.00 85.70 ? 566 SER C O 1 ATOM 3951 C CB . SER A 1 501 ? -171.589 -136.380 192.749 1.00 77.04 ? 566 SER C CB 1 ATOM 3952 O OG . SER A 1 501 ? -170.809 -137.561 192.628 1.00 82.44 ? 566 SER C OG 1 ATOM 3953 N N . SER A 1 502 ? -170.425 -137.291 195.666 1.00 87.66 ? 567 SER C N 1 ATOM 3954 C CA . SER A 1 502 ? -170.016 -138.395 196.521 1.00 85.56 ? 567 SER C CA 1 ATOM 3955 C C . SER A 1 502 ? -170.265 -138.074 197.987 1.00 84.74 ? 567 SER C C 1 ATOM 3956 O O . SER A 1 502 ? -170.832 -138.881 198.729 1.00 83.30 ? 567 SER C O 1 ATOM 3957 C CB . SER A 1 502 ? -168.535 -138.715 196.300 1.00 85.28 ? 567 SER C CB 1 ATOM 3958 O OG . SER A 1 502 ? -167.748 -137.535 196.294 1.00 87.77 ? 567 SER C OG 1 ATOM 3959 N N . VAL A 1 503 ? -169.858 -136.876 198.384 1.00 79.24 ? 568 VAL C N 1 ATOM 3960 C CA . VAL A 1 503 ? -170.023 -136.425 199.751 1.00 85.45 ? 568 VAL C CA 1 ATOM 3961 C C . VAL A 1 503 ? -171.494 -136.462 200.161 1.00 88.44 ? 568 VAL C C 1 ATOM 3962 O O . VAL A 1 503 ? -171.838 -136.704 201.314 1.00 88.71 ? 568 VAL C O 1 ATOM 3963 C CB . VAL A 1 503 ? -169.505 -134.988 199.918 1.00 84.17 ? 568 VAL C CB 1 ATOM 3964 C CG1 . VAL A 1 503 ? -169.898 -134.459 201.273 1.00 92.25 ? 568 VAL C CG1 1 ATOM 3965 C CG2 . VAL A 1 503 ? -168.016 -134.944 199.735 1.00 86.82 ? 568 VAL C CG2 1 ATOM 3966 N N . VAL A 1 504 ? -172.357 -136.210 199.189 1.00 91.76 ? 569 VAL C N 1 ATOM 3967 C CA . VAL A 1 504 ? -173.784 -136.089 199.435 1.00 89.22 ? 569 VAL C CA 1 ATOM 3968 C C . VAL A 1 504 ? -174.405 -137.435 199.800 1.00 90.74 ? 569 VAL C C 1 ATOM 3969 O O . VAL A 1 504 ? -175.450 -137.488 200.444 1.00 91.97 ? 569 VAL C O 1 ATOM 3970 C CB . VAL A 1 504 ? -174.501 -135.488 198.216 1.00 81.63 ? 569 VAL C CB 1 ATOM 3971 C CG1 . VAL A 1 504 ? -174.832 -136.583 197.203 1.00 80.70 ? 569 VAL C CG1 1 ATOM 3972 C CG2 . VAL A 1 504 ? -175.738 -134.734 198.658 1.00 79.03 ? 569 VAL C CG2 1 ATOM 3973 N N . MET A 1 505 ? -173.757 -138.523 199.402 1.00 89.33 ? 570 MET C N 1 ATOM 3974 C CA . MET A 1 505 ? -174.244 -139.851 199.746 1.00 89.77 ? 570 MET C CA 1 ATOM 3975 C C . MET A 1 505 ? -174.285 -140.055 201.268 1.00 91.55 ? 570 MET C C 1 ATOM 3976 O O . MET A 1 505 ? -175.138 -140.770 201.790 1.00 93.09 ? 570 MET C O 1 ATOM 3977 C CB . MET A 1 505 ? -173.358 -140.920 199.103 1.00 85.71 ? 570 MET C CB 1 ATOM 3978 C CG . MET A 1 505 ? -173.292 -140.840 197.597 1.00 93.34 ? 570 MET C CG 1 ATOM 3979 S SD . MET A 1 505 ? -174.857 -141.303 196.828 1.00 112.84 ? 570 MET C SD 1 ATOM 3980 C CE . MET A 1 505 ? -175.028 -143.000 197.376 1.00 103.61 ? 570 MET C CE 1 ATOM 3981 N N . ILE A 1 506 ? -173.355 -139.432 201.981 1.00 87.87 ? 571 ILE C N 1 ATOM 3982 C CA . ILE A 1 506 ? -173.288 -139.586 203.431 1.00 91.05 ? 571 ILE C CA 1 ATOM 3983 C C . ILE A 1 506 ? -174.562 -139.108 204.135 1.00 96.34 ? 571 ILE C C 1 ATOM 3984 O O . ILE A 1 506 ? -175.139 -139.849 204.937 1.00 100.24 ? 571 ILE C O 1 ATOM 3985 C CB . ILE A 1 506 ? -172.066 -138.840 204.006 1.00 88.59 ? 571 ILE C CB 1 ATOM 3986 C CG1 . ILE A 1 506 ? -170.782 -139.491 203.512 1.00 87.84 ? 571 ILE C CG1 1 ATOM 3987 C CG2 . ILE A 1 506 ? -172.091 -138.820 205.524 1.00 80.74 ? 571 ILE C CG2 1 ATOM 3988 C CD1 . ILE A 1 506 ? -169.557 -138.704 203.861 1.00 82.92 ? 571 ILE C CD1 1 ATOM 3989 N N . PRO A 1 507 ? -175.017 -137.882 203.834 1.00 96.48 ? 572 PRO C N 1 ATOM 3990 C CA . PRO A 1 507 ? -176.244 -137.437 204.497 1.00 96.37 ? 572 PRO C CA 1 ATOM 3991 C C . PRO A 1 507 ? -177.474 -137.992 203.791 1.00 93.79 ? 572 PRO C C 1 ATOM 3992 O O . PRO A 1 507 ? -178.493 -138.249 204.430 1.00 90.71 ? 572 PRO C O 1 ATOM 3993 C CB . PRO A 1 507 ? -176.164 -135.911 204.395 1.00 86.61 ? 572 PRO C CB 1 ATOM 3994 C CG . PRO A 1 507 ? -175.375 -135.677 203.163 1.00 89.16 ? 572 PRO C CG 1 ATOM 3995 C CD . PRO A 1 507 ? -174.387 -136.804 203.050 1.00 92.76 ? 572 PRO C CD 1 ATOM 3996 N N . ALA A 1 508 ? -177.359 -138.185 202.480 1.00 92.42 ? 573 ALA C N 1 ATOM 3997 C CA . ALA A 1 508 ? -178.454 -138.742 201.695 1.00 91.22 ? 573 ALA C CA 1 ATOM 3998 C C . ALA A 1 508 ? -178.833 -140.084 202.267 1.00 96.91 ? 573 ALA C C 1 ATOM 3999 O O . ALA A 1 508 ? -179.932 -140.267 202.774 1.00 102.14 ? 573 ALA C O 1 ATOM 4000 C CB . ALA A 1 508 ? -178.070 -138.888 200.233 1.00 87.90 ? 573 ALA C CB 1 ATOM 4001 N N . VAL A 1 509 ? -177.892 -141.012 202.221 1.00 101.37 ? 574 VAL C N 1 ATOM 4002 C CA . VAL A 1 509 ? -178.149 -142.366 202.674 1.00 105.71 ? 574 VAL C CA 1 ATOM 4003 C C . VAL A 1 509 ? -178.530 -142.400 204.157 1.00 98.83 ? 574 VAL C C 1 ATOM 4004 O O . VAL A 1 509 ? -179.301 -143.245 204.577 1.00 97.79 ? 574 VAL C O 1 ATOM 4005 C CB . VAL A 1 509 ? -176.925 -143.267 202.413 1.00 101.63 ? 574 VAL C CB 1 ATOM 4006 C CG1 . VAL A 1 509 ? -177.059 -144.583 203.161 1.00 102.47 ? 574 VAL C CG1 1 ATOM 4007 C CG2 . VAL A 1 509 ? -176.760 -143.498 200.916 1.00 97.38 ? 574 VAL C CG2 1 ATOM 4008 N N . ALA A 1 510 ? -178.007 -141.475 204.949 1.00 97.01 ? 575 ALA C N 1 ATOM 4009 C CA . ALA A 1 510 ? -178.394 -141.429 206.353 1.00 97.64 ? 575 ALA C CA 1 ATOM 4010 C C . ALA A 1 510 ? -179.860 -141.051 206.470 1.00 106.22 ? 575 ALA C C 1 ATOM 4011 O O . ALA A 1 510 ? -180.585 -141.590 207.304 1.00 111.41 ? 575 ALA C O 1 ATOM 4012 C CB . ALA A 1 510 ? -177.531 -140.443 207.127 1.00 91.51 ? 575 ALA C CB 1 ATOM 4013 N N . ILE A 1 511 ? -180.298 -140.132 205.614 1.00 108.14 ? 576 ILE C N 1 ATOM 4014 C CA . ILE A 1 511 ? -181.679 -139.657 205.635 1.00 102.06 ? 576 ILE C CA 1 ATOM 4015 C C . ILE A 1 511 ? -182.623 -140.765 205.187 1.00 102.17 ? 576 ILE C C 1 ATOM 4016 O O . ILE A 1 511 ? -183.663 -140.996 205.793 1.00 106.84 ? 576 ILE C O 1 ATOM 4017 C CB . ILE A 1 511 ? -181.868 -138.413 204.723 1.00 100.65 ? 576 ILE C CB 1 ATOM 4018 C CG1 . ILE A 1 511 ? -181.140 -137.191 205.295 1.00 98.48 ? 576 ILE C CG1 1 ATOM 4019 C CG2 . ILE A 1 511 ? -183.331 -138.102 204.538 1.00 101.93 ? 576 ILE C CG2 1 ATOM 4020 C CD1 . ILE A 1 511 ? -181.569 -136.826 206.703 1.00 102.94 ? 576 ILE C CD1 1 ATOM 4021 N N . PHE A 1 512 ? -182.238 -141.453 204.123 1.00 100.90 ? 577 PHE C N 1 ATOM 4022 C CA . PHE A 1 512 ? -183.029 -142.541 203.569 1.00 105.29 ? 577 PHE C CA 1 ATOM 4023 C C . PHE A 1 512 ? -183.127 -143.758 204.495 1.00 112.30 ? 577 PHE C C 1 ATOM 4024 O O . PHE A 1 512 ? -184.139 -144.452 204.511 1.00 115.43 ? 577 PHE C O 1 ATOM 4025 C CB . PHE A 1 512 ? -182.433 -142.956 202.223 1.00 106.33 ? 577 PHE C CB 1 ATOM 4026 C CG . PHE A 1 512 ? -183.044 -144.190 201.643 1.00 112.72 ? 577 PHE C CG 1 ATOM 4027 C CD1 . PHE A 1 512 ? -184.052 -144.096 200.696 1.00 117.25 ? 577 PHE C CD1 1 ATOM 4028 C CD2 . PHE A 1 512 ? -182.607 -145.448 202.033 1.00 113.27 ? 577 PHE C CD2 1 ATOM 4029 C CE1 . PHE A 1 512 ? -184.621 -145.234 200.152 1.00 121.07 ? 577 PHE C CE1 1 ATOM 4030 C CE2 . PHE A 1 512 ? -183.169 -146.586 201.499 1.00 114.72 ? 577 PHE C CE2 1 ATOM 4031 C CZ . PHE A 1 512 ? -184.177 -146.482 200.554 1.00 117.91 ? 577 PHE C CZ 1 ATOM 4032 N N . LYS A 1 513 ? -182.061 -144.040 205.240 1.00 116.00 ? 578 LYS C N 1 ATOM 4033 C CA . LYS A 1 513 ? -182.066 -145.171 206.171 1.00 115.23 ? 578 LYS C CA 1 ATOM 4034 C C . LYS A 1 513 ? -182.968 -144.898 207.372 1.00 116.84 ? 578 LYS C C 1 ATOM 4035 O O . LYS A 1 513 ? -183.573 -145.815 207.923 1.00 121.86 ? 578 LYS C O 1 ATOM 4036 C CB . LYS A 1 513 ? -180.645 -145.504 206.654 1.00 111.45 ? 578 LYS C CB 1 ATOM 4037 C CG . LYS A 1 513 ? -179.660 -145.904 205.549 1.00 111.94 ? 578 LYS C CG 1 ATOM 4038 C CD . LYS A 1 513 ? -179.974 -147.258 204.925 1.00 119.22 ? 578 LYS C CD 1 ATOM 4039 C CE . LYS A 1 513 ? -179.463 -148.407 205.782 1.00 118.33 ? 578 LYS C CE 1 ATOM 4040 N NZ . LYS A 1 513 ? -179.420 -149.675 205.000 1.00 119.26 ? 578 LYS C NZ 1 ATOM 4041 N N . LEU A 1 514 ? -183.060 -143.631 207.769 1.00 113.70 ? 579 LEU C N 1 ATOM 4042 C CA . LEU A 1 514 ? -183.916 -143.245 208.889 1.00 117.34 ? 579 LEU C CA 1 ATOM 4043 C C . LEU A 1 514 ? -185.390 -143.485 208.559 1.00 122.08 ? 579 LEU C C 1 ATOM 4044 O O . LEU A 1 514 ? -186.213 -143.726 209.443 1.00 125.52 ? 579 LEU C O 1 ATOM 4045 C CB . LEU A 1 514 ? -183.703 -141.774 209.260 1.00 111.48 ? 579 LEU C CB 1 ATOM 4046 C CG . LEU A 1 514 ? -182.482 -141.383 210.091 1.00 106.13 ? 579 LEU C CG 1 ATOM 4047 C CD1 . LEU A 1 514 ? -182.588 -139.953 210.584 1.00 98.59 ? 579 LEU C CD1 1 ATOM 4048 C CD2 . LEU A 1 514 ? -182.303 -142.320 211.262 1.00 116.41 ? 579 LEU C CD2 1 ATOM 4049 N N . LEU A 1 515 ? -185.714 -143.428 207.275 1.00 119.93 ? 580 LEU C N 1 ATOM 4050 C CA . LEU A 1 515 ? -187.101 -143.459 206.844 1.00 119.62 ? 580 LEU C CA 1 ATOM 4051 C C . LEU A 1 515 ? -187.531 -144.851 206.392 1.00 122.21 ? 580 LEU C C 1 ATOM 4052 O O . LEU A 1 515 ? -188.527 -145.001 205.678 1.00 126.86 ? 580 LEU C O 1 ATOM 4053 C CB . LEU A 1 515 ? -187.323 -142.436 205.728 1.00 117.59 ? 580 LEU C CB 1 ATOM 4054 C CG . LEU A 1 515 ? -186.941 -141.005 206.122 1.00 111.82 ? 580 LEU C CG 1 ATOM 4055 C CD1 . LEU A 1 515 ? -187.467 -140.012 205.101 1.00 98.99 ? 580 LEU C CD1 1 ATOM 4056 C CD2 . LEU A 1 515 ? -187.428 -140.668 207.529 1.00 108.09 ? 580 LEU C CD2 1 ATOM 4057 N N . SER A 1 516 ? -186.765 -145.866 206.778 1.00 119.89 ? 581 SER C N 1 ATOM 4058 C CA . SER A 1 516 ? -187.196 -147.245 206.581 1.00 123.57 ? 581 SER C CA 1 ATOM 4059 C C . SER A 1 516 ? -187.293 -147.952 207.929 1.00 124.80 ? 581 SER C C 1 ATOM 4060 O O . SER A 1 516 ? -187.649 -149.131 208.007 1.00 128.44 ? 581 SER C O 1 ATOM 4061 C CB . SER A 1 516 ? -186.231 -147.979 205.653 1.00 123.65 ? 581 SER C CB 1 ATOM 4062 O OG . SER A 1 516 ? -185.936 -147.187 204.513 1.00 116.22 ? 581 SER C OG 1 ATOM 4063 N N . THR A 1 517 ? -186.963 -147.211 208.985 1.00 123.71 ? 582 THR C N 1 ATOM 4064 C CA . THR A 1 517 ? -186.873 -147.754 210.339 1.00 126.58 ? 582 THR C CA 1 ATOM 4065 C C . THR A 1 517 ? -188.057 -147.358 211.224 1.00 129.25 ? 582 THR C C 1 ATOM 4066 O O . THR A 1 517 ? -188.424 -146.184 211.292 1.00 127.74 ? 582 THR C O 1 ATOM 4067 C CB . THR A 1 517 ? -185.561 -147.328 211.013 1.00 128.82 ? 582 THR C CB 1 ATOM 4068 O OG1 . THR A 1 517 ? -185.069 -146.130 210.396 1.00 128.18 ? 582 THR C OG1 1 ATOM 4069 C CG2 . THR A 1 517 ? -184.518 -148.427 210.850 1.00 118.95 ? 582 THR C CG2 1 ATOM 4070 N N . PRO A 1 518 ? -188.657 -148.354 211.895 1.00 129.26 ? 583 PRO C N 1 ATOM 4071 C CA . PRO A 1 518 ? -189.946 -148.240 212.585 1.00 125.66 ? 583 PRO C CA 1 ATOM 4072 C C . PRO A 1 518 ? -190.088 -147.158 213.663 1.00 125.46 ? 583 PRO C C 1 ATOM 4073 O O . PRO A 1 518 ? -191.075 -146.428 213.648 1.00 127.08 ? 583 PRO C O 1 ATOM 4074 C CB . PRO A 1 518 ? -190.088 -149.614 213.253 1.00 129.65 ? 583 PRO C CB 1 ATOM 4075 C CG . PRO A 1 518 ? -188.676 -150.095 213.424 1.00 129.26 ? 583 PRO C CG 1 ATOM 4076 C CD . PRO A 1 518 ? -188.007 -149.651 212.166 1.00 129.03 ? 583 PRO C CD 1 ATOM 4077 N N . GLY A 1 519 ? -189.078 -146.969 214.502 1.00 124.08 ? 584 GLY C N 1 ATOM 4078 C CA . GLY A 1 519 ? -189.343 -146.381 215.805 1.00 128.30 ? 584 GLY C CA 1 ATOM 4079 C C . GLY A 1 519 ? -189.364 -144.871 215.922 1.00 123.68 ? 584 GLY C C 1 ATOM 4080 O O . GLY A 1 519 ? -189.340 -144.147 214.928 1.00 124.72 ? 584 GLY C O 1 ATOM 4081 N N . SER A 1 520 ? -189.414 -144.407 217.165 1.00 120.98 ? 585 SER C N 1 ATOM 4082 C CA . SER A 1 520 ? -189.214 -143.006 217.501 1.00 126.30 ? 585 SER C CA 1 ATOM 4083 C C . SER A 1 520 ? -187.752 -142.632 217.274 1.00 134.67 ? 585 SER C C 1 ATOM 4084 O O . SER A 1 520 ? -186.887 -143.508 217.173 1.00 136.79 ? 585 SER C O 1 ATOM 4085 C CB . SER A 1 520 ? -189.589 -142.730 218.949 1.00 129.16 ? 585 SER C CB 1 ATOM 4086 O OG . SER A 1 520 ? -188.829 -141.641 219.454 1.00 128.50 ? 585 SER C OG 1 ATOM 4087 N N . LEU A 1 521 ? -187.471 -141.344 217.125 1.00 131.79 ? 586 LEU C N 1 ATOM 4088 C CA . LEU A 1 521 ? -186.128 -140.931 216.725 1.00 132.06 ? 586 LEU C CA 1 ATOM 4089 C C . LEU A 1 521 ? -185.044 -141.093 217.798 1.00 131.92 ? 586 LEU C C 1 ATOM 4090 O O . LEU A 1 521 ? -183.864 -141.126 217.461 1.00 136.75 ? 586 LEU C O 1 ATOM 4091 C CB . LEU A 1 521 ? -186.154 -139.491 216.213 1.00 132.41 ? 586 LEU C CB 1 ATOM 4092 C CG . LEU A 1 521 ? -186.605 -139.437 214.744 1.00 136.71 ? 586 LEU C CG 1 ATOM 4093 C CD1 . LEU A 1 521 ? -188.068 -139.872 214.587 1.00 138.57 ? 586 LEU C CD1 1 ATOM 4094 C CD2 . LEU A 1 521 ? -186.382 -138.063 214.145 1.00 132.41 ? 586 LEU C CD2 1 ATOM 4095 N N . ARG A 1 522 ? -185.402 -141.188 219.076 1.00 133.68 ? 587 ARG C N 1 ATOM 4096 C CA . ARG A 1 522 ? -184.396 -141.611 220.053 1.00 126.49 ? 587 ARG C CA 1 ATOM 4097 C C . ARG A 1 522 ? -184.153 -143.105 219.841 1.00 129.04 ? 587 ARG C C 1 ATOM 4098 O O . ARG A 1 522 ? -183.017 -143.588 219.883 1.00 126.42 ? 587 ARG C O 1 ATOM 4099 C CB . ARG A 1 522 ? -184.841 -141.318 221.488 1.00 116.11 ? 587 ARG C CB 1 ATOM 4100 N N . GLN A 1 523 ? -185.248 -143.816 219.583 1.00 129.53 ? 588 GLN C N 1 ATOM 4101 C CA . GLN A 1 523 ? -185.240 -145.248 219.304 1.00 128.06 ? 588 GLN C CA 1 ATOM 4102 C C . GLN A 1 523 ? -184.559 -145.578 217.977 1.00 126.40 ? 588 GLN C C 1 ATOM 4103 O O . GLN A 1 523 ? -184.084 -146.697 217.776 1.00 124.54 ? 588 GLN C O 1 ATOM 4104 C CB . GLN A 1 523 ? -186.682 -145.790 219.309 1.00 131.51 ? 588 GLN C CB 1 ATOM 4105 C CG . GLN A 1 523 ? -186.854 -147.158 218.652 1.00 135.75 ? 588 GLN C CG 1 ATOM 4106 C CD . GLN A 1 523 ? -187.391 -148.218 219.603 1.00 140.51 ? 588 GLN C CD 1 ATOM 4107 O OE1 . GLN A 1 523 ? -186.754 -149.253 219.823 1.00 141.71 ? 588 GLN C OE1 1 ATOM 4108 N NE2 . GLN A 1 523 ? -188.573 -147.970 220.163 1.00 131.67 ? 588 GLN C NE2 1 ATOM 4109 N N . ARG A 1 524 ? -184.526 -144.616 217.061 1.00 128.15 ? 589 ARG C N 1 ATOM 4110 C CA . ARG A 1 524 ? -184.028 -144.912 215.720 1.00 128.64 ? 589 ARG C CA 1 ATOM 4111 C C . ARG A 1 524 ? -182.550 -144.565 215.494 1.00 123.39 ? 589 ARG C C 1 ATOM 4112 O O . ARG A 1 524 ? -181.903 -145.164 214.634 1.00 118.39 ? 589 ARG C O 1 ATOM 4113 C CB . ARG A 1 524 ? -184.882 -144.209 214.673 1.00 125.78 ? 589 ARG C CB 1 ATOM 4114 C CG . ARG A 1 524 ? -185.038 -145.034 213.402 1.00 126.33 ? 589 ARG C CG 1 ATOM 4115 C CD . ARG A 1 524 ? -186.342 -144.704 212.700 1.00 129.83 ? 589 ARG C CD 1 ATOM 4116 N NE . ARG A 1 524 ? -186.395 -143.295 212.333 1.00 138.91 ? 589 ARG C NE 1 ATOM 4117 C CZ . ARG A 1 524 ? -187.500 -142.557 212.348 1.00 140.56 ? 589 ARG C CZ 1 ATOM 4118 N NH1 . ARG A 1 524 ? -187.441 -141.275 211.992 1.00 143.34 ? 589 ARG C NH1 1 ATOM 4119 N NH2 . ARG A 1 524 ? -188.657 -143.101 212.716 1.00 130.28 ? 589 ARG C NH2 1 ATOM 4120 N N . PHE A 1 525 ? -182.011 -143.602 216.235 1.00 122.82 ? 590 PHE C N 1 ATOM 4121 C CA . PHE A 1 525 ? -180.572 -143.376 216.165 1.00 120.13 ? 590 PHE C CA 1 ATOM 4122 C C . PHE A 1 525 ? -179.862 -144.595 216.730 1.00 119.33 ? 590 PHE C C 1 ATOM 4123 O O . PHE A 1 525 ? -178.780 -144.962 216.277 1.00 121.64 ? 590 PHE C O 1 ATOM 4124 C CB . PHE A 1 525 ? -180.150 -142.116 216.921 1.00 118.26 ? 590 PHE C CB 1 ATOM 4125 C CG . PHE A 1 525 ? -180.544 -140.832 216.236 1.00 126.39 ? 590 PHE C CG 1 ATOM 4126 C CD1 . PHE A 1 525 ? -180.862 -140.811 214.883 1.00 123.56 ? 590 PHE C CD1 1 ATOM 4127 C CD2 . PHE A 1 525 ? -180.601 -139.642 216.952 1.00 126.52 ? 590 PHE C CD2 1 ATOM 4128 C CE1 . PHE A 1 525 ? -181.232 -139.629 214.258 1.00 117.55 ? 590 PHE C CE1 1 ATOM 4129 C CE2 . PHE A 1 525 ? -180.968 -138.461 216.333 1.00 124.40 ? 590 PHE C CE2 1 ATOM 4130 C CZ . PHE A 1 525 ? -181.283 -138.452 214.988 1.00 119.07 ? 590 PHE C CZ 1 ATOM 4131 N N . THR A 1 526 ? -180.486 -145.235 217.712 1.00 120.14 ? 591 THR C N 1 ATOM 4132 C CA . THR A 1 526 ? -179.882 -146.399 218.340 1.00 115.28 ? 591 THR C CA 1 ATOM 4133 C C . THR A 1 526 ? -179.895 -147.632 217.435 1.00 110.70 ? 591 THR C C 1 ATOM 4134 O O . THR A 1 526 ? -178.908 -148.363 217.379 1.00 111.18 ? 591 THR C O 1 ATOM 4135 C CB . THR A 1 526 ? -180.573 -146.727 219.659 1.00 111.85 ? 591 THR C CB 1 ATOM 4136 O OG1 . THR A 1 526 ? -181.987 -146.725 219.454 1.00 124.45 ? 591 THR C OG1 1 ATOM 4137 C CG2 . THR A 1 526 ? -180.227 -145.685 220.708 1.00 108.20 ? 591 THR C CG2 1 ATOM 4138 N N . ILE A 1 527 ? -180.985 -147.868 216.713 1.00 109.19 ? 592 ILE C N 1 ATOM 4139 C CA . ILE A 1 527 ? -181.020 -149.040 215.843 1.00 110.44 ? 592 ILE C CA 1 ATOM 4140 C C . ILE A 1 527 ? -180.014 -148.894 214.701 1.00 111.29 ? 592 ILE C C 1 ATOM 4141 O O . ILE A 1 527 ? -179.516 -149.889 214.153 1.00 108.15 ? 592 ILE C O 1 ATOM 4142 C CB . ILE A 1 527 ? -182.424 -149.300 215.259 1.00 112.78 ? 592 ILE C CB 1 ATOM 4143 C CG1 . ILE A 1 527 ? -182.398 -150.532 214.341 1.00 109.63 ? 592 ILE C CG1 1 ATOM 4144 C CG2 . ILE A 1 527 ? -182.931 -148.078 214.512 1.00 121.38 ? 592 ILE C CG2 1 ATOM 4145 C CD1 . ILE A 1 527 ? -183.745 -150.910 213.758 1.00 107.37 ? 592 ILE C CD1 1 ATOM 4146 N N . LEU A 1 528 ? -179.713 -147.647 214.346 1.00 112.42 ? 593 LEU C N 1 ATOM 4147 C CA . LEU A 1 528 ? -178.800 -147.371 213.238 1.00 107.81 ? 593 LEU C CA 1 ATOM 4148 C C . LEU A 1 528 ? -177.372 -147.069 213.712 1.00 104.20 ? 593 LEU C C 1 ATOM 4149 O O . LEU A 1 528 ? -176.455 -146.972 212.895 1.00 103.71 ? 593 LEU C O 1 ATOM 4150 C CB . LEU A 1 528 ? -179.347 -146.218 212.386 1.00 105.51 ? 593 LEU C CB 1 ATOM 4151 C CG . LEU A 1 528 ? -180.577 -146.560 211.529 1.00 103.43 ? 593 LEU C CG 1 ATOM 4152 C CD1 . LEU A 1 528 ? -181.259 -145.311 210.997 1.00 110.26 ? 593 LEU C CD1 1 ATOM 4153 C CD2 . LEU A 1 528 ? -180.208 -147.487 210.382 1.00 95.78 ? 593 LEU C CD2 1 ATOM 4154 N N . THR A 1 529 ? -177.181 -146.927 215.022 1.00 102.91 ? 594 THR C N 1 ATOM 4155 C CA . THR A 1 529 ? -175.832 -146.850 215.584 1.00 103.00 ? 594 THR C CA 1 ATOM 4156 C C . THR A 1 529 ? -175.437 -148.110 216.368 1.00 102.62 ? 594 THR C C 1 ATOM 4157 O O . THR A 1 529 ? -174.441 -148.104 217.100 1.00 103.78 ? 594 THR C O 1 ATOM 4158 C CB . THR A 1 529 ? -175.657 -145.611 216.503 1.00 105.23 ? 594 THR C CB 1 ATOM 4159 O OG1 . THR A 1 529 ? -176.578 -145.673 217.599 1.00 109.95 ? 594 THR C OG1 1 ATOM 4160 C CG2 . THR A 1 529 ? -175.874 -144.334 215.725 1.00 98.96 ? 594 THR C CG2 1 ATOM 4161 N N . THR A 1 530 ? -176.218 -149.181 216.244 1.00 100.27 ? 595 THR C N 1 ATOM 4162 C CA . THR A 1 530 ? -175.798 -150.475 216.798 1.00 105.37 ? 595 THR C CA 1 ATOM 4163 C C . THR A 1 530 ? -175.180 -151.350 215.705 1.00 100.88 ? 595 THR C C 1 ATOM 4164 O O . THR A 1 530 ? -175.812 -151.649 214.682 1.00 95.34 ? 595 THR C O 1 ATOM 4165 C CB . THR A 1 530 ? -176.959 -151.233 217.491 1.00 101.77 ? 595 THR C CB 1 ATOM 4166 O OG1 . THR A 1 530 ? -178.078 -151.338 216.599 1.00 107.38 ? 595 THR C OG1 1 ATOM 4167 C CG2 . THR A 1 530 ? -177.366 -150.522 218.780 1.00 91.35 ? 595 THR C CG2 1 ATOM 4168 N N . PRO A 1 531 ? -173.927 -151.743 215.924 1.00 94.61 ? 596 PRO C N 1 ATOM 4169 C CA . PRO A 1 531 ? -173.098 -152.514 215.003 1.00 93.28 ? 596 PRO C CA 1 ATOM 4170 C C . PRO A 1 531 ? -173.673 -153.886 214.693 1.00 97.57 ? 596 PRO C C 1 ATOM 4171 O O . PRO A 1 531 ? -174.274 -154.514 215.545 1.00 108.25 ? 596 PRO C O 1 ATOM 4172 C CB . PRO A 1 531 ? -171.775 -152.651 215.773 1.00 97.97 ? 596 PRO C CB 1 ATOM 4173 C CG . PRO A 1 531 ? -171.757 -151.480 216.667 1.00 96.48 ? 596 PRO C CG 1 ATOM 4174 C CD . PRO A 1 531 ? -173.164 -151.285 217.101 1.00 94.09 ? 596 PRO C CD 1 ATOM 4175 N N . TRP A 1 532 ? -173.458 -154.330 213.467 1.00 95.34 ? 597 TRP C N 1 ATOM 4176 C CA . TRP A 1 532 ? -173.927 -155.615 212.994 1.00 103.26 ? 597 TRP C CA 1 ATOM 4177 C C . TRP A 1 532 ? -173.337 -156.776 213.793 1.00 116.34 ? 597 TRP C C 1 ATOM 4178 O O . TRP A 1 532 ? -173.945 -157.844 213.908 1.00 123.98 ? 597 TRP C O 1 ATOM 4179 C CB . TRP A 1 532 ? -173.569 -155.761 211.527 1.00 104.41 ? 597 TRP C CB 1 ATOM 4180 C CG . TRP A 1 532 ? -174.013 -157.015 210.887 1.00 104.10 ? 597 TRP C CG 1 ATOM 4181 C CD1 . TRP A 1 532 ? -175.232 -157.258 210.321 1.00 110.40 ? 597 TRP C CD1 1 ATOM 4182 C CD2 . TRP A 1 532 ? -173.241 -158.202 210.709 1.00 106.23 ? 597 TRP C CD2 1 ATOM 4183 N NE1 . TRP A 1 532 ? -175.269 -158.530 209.808 1.00 111.07 ? 597 TRP C NE1 1 ATOM 4184 C CE2 . TRP A 1 532 ? -174.058 -159.131 210.034 1.00 109.51 ? 597 TRP C CE2 1 ATOM 4185 C CE3 . TRP A 1 532 ? -171.939 -158.575 211.059 1.00 108.67 ? 597 TRP C CE3 1 ATOM 4186 C CZ2 . TRP A 1 532 ? -173.614 -160.410 209.701 1.00 115.00 ? 597 TRP C CZ2 1 ATOM 4187 C CZ3 . TRP A 1 532 ? -171.501 -159.844 210.729 1.00 107.19 ? 597 TRP C CZ3 1 ATOM 4188 C CH2 . TRP A 1 532 ? -172.334 -160.745 210.058 1.00 113.33 ? 597 TRP C CH2 1 ATOM 4189 N N . ARG A 1 533 ? -172.148 -156.558 214.342 1.00 118.79 ? 598 ARG C N 1 ATOM 4190 C CA . ARG A 1 533 ? -171.466 -157.538 215.186 1.00 120.42 ? 598 ARG C CA 1 ATOM 4191 C C . ARG A 1 533 ? -172.283 -157.860 216.435 1.00 124.86 ? 598 ARG C C 1 ATOM 4192 O O . ARG A 1 533 ? -172.267 -158.993 216.925 1.00 128.96 ? 598 ARG C O 1 ATOM 4193 C CB . ARG A 1 533 ? -170.081 -157.004 215.587 1.00 118.89 ? 598 ARG C CB 1 ATOM 4194 C CG . ARG A 1 533 ? -169.245 -157.929 216.452 1.00 121.08 ? 598 ARG C CG 1 ATOM 4195 C CD . ARG A 1 533 ? -168.616 -159.053 215.638 1.00 119.82 ? 598 ARG C CD 1 ATOM 4196 N NE . ARG A 1 533 ? -168.005 -160.054 216.511 1.00 124.63 ? 598 ARG C NE 1 ATOM 4197 C CZ . ARG A 1 533 ? -168.200 -161.370 216.414 1.00 129.81 ? 598 ARG C CZ 1 ATOM 4198 N NH1 . ARG A 1 533 ? -168.993 -161.868 215.465 1.00 127.79 ? 598 ARG C NH1 1 ATOM 4199 N NH2 . ARG A 1 533 ? -167.593 -162.194 217.269 1.00 120.60 ? 598 ARG C NH2 1 ATOM 4200 N N . ASP A 1 534 ? -173.009 -156.862 216.935 1.00 124.34 ? 599 ASP C N 1 ATOM 4201 C CA . ASP A 1 534 ? -173.748 -156.999 218.189 1.00 126.53 ? 599 ASP C CA 1 ATOM 4202 C C . ASP A 1 534 ? -175.174 -157.546 218.008 1.00 131.06 ? 599 ASP C C 1 ATOM 4203 O O . ASP A 1 534 ? -175.687 -158.239 218.892 1.00 137.12 ? 599 ASP C O 1 ATOM 4204 C CB . ASP A 1 534 ? -173.784 -155.649 218.922 1.00 114.57 ? 599 ASP C CB 1 ATOM 4205 C CG . ASP A 1 534 ? -172.387 -155.121 219.238 1.00 114.35 ? 599 ASP C CG 1 ATOM 4206 O OD1 . ASP A 1 534 ? -171.419 -155.887 219.048 1.00 116.18 ? 599 ASP C OD1 1 ATOM 4207 O OD2 . ASP A 1 534 ? -172.245 -153.954 219.677 1.00 111.02 ? 599 ASP C OD2 1 ATOM 4208 N N . GLN A 1 535 ? -175.805 -157.244 216.874 1.00 128.42 ? 600 GLN C N 1 ATOM 4209 C CA . GLN A 1 535 ? -177.176 -157.698 216.617 1.00 137.21 ? 600 GLN C CA 1 ATOM 4210 C C . GLN A 1 535 ? -177.276 -159.224 216.460 1.00 142.36 ? 600 GLN C C 1 ATOM 4211 O O . GLN A 1 535 ? -178.292 -159.836 216.803 1.00 143.05 ? 600 GLN C O 1 ATOM 4212 C CB . GLN A 1 535 ? -177.736 -157.010 215.364 1.00 127.93 ? 600 GLN C CB 1 ATOM 4213 N N . GLN A 1 536 ? -176.211 -159.827 215.941 1.00 141.24 ? 601 GLN C N 1 ATOM 4214 C CA . GLN A 1 536 ? -176.177 -161.259 215.645 1.00 143.48 ? 601 GLN C CA 1 ATOM 4215 C C . GLN A 1 536 ? -175.741 -162.158 216.816 1.00 145.90 ? 601 GLN C C 1 ATOM 4216 O O . GLN A 1 536 ? -175.826 -163.389 216.717 1.00 144.39 ? 601 GLN C O 1 ATOM 4217 C CB . GLN A 1 536 ? -175.245 -161.495 214.457 1.00 138.49 ? 601 GLN C CB 1 ATOM 4218 C CG . GLN A 1 536 ? -173.850 -160.942 214.683 1.00 133.37 ? 601 GLN C CG 1 ATOM 4219 C CD . GLN A 1 536 ? -172.841 -161.548 213.743 1.00 138.15 ? 601 GLN C CD 1 ATOM 4220 O OE1 . GLN A 1 536 ? -173.204 -162.078 212.692 1.00 136.45 ? 601 GLN C OE1 1 ATOM 4221 N NE2 . GLN A 1 536 ? -171.563 -161.489 214.119 1.00 140.40 ? 601 GLN C NE2 1 ATOM 4222 N N . LEU A 1 537 ? -175.282 -161.536 217.906 1.00 146.07 ? 602 LEU C N 1 ATOM 4223 C CA . LEU A 1 537 ? -174.620 -162.224 219.026 1.00 147.23 ? 602 LEU C CA 1 ATOM 4224 C C . LEU A 1 537 ? -173.583 -163.249 218.539 1.00 148.97 ? 602 LEU C C 1 ATOM 4225 O O . LEU A 1 537 ? -173.862 -164.442 218.394 1.00 149.41 ? 602 LEU C O 1 ATOM 4226 C CB . LEU A 1 537 ? -175.653 -162.887 219.965 1.00 145.91 ? 602 LEU C CB 1 ATOM 4227 C CG . LEU A 1 537 ? -176.772 -163.839 219.500 1.00 144.33 ? 602 LEU C CG 1 ATOM 4228 C CD1 . LEU A 1 537 ? -176.335 -165.309 219.486 1.00 139.36 ? 602 LEU C CD1 1 ATOM 4229 C CD2 . LEU A 1 537 ? -178.016 -163.661 220.367 1.00 136.53 ? 602 LEU C CD2 1 ATOM 4230 N N . GLU B 2 1 ? -155.824 -179.145 220.364 1.00 84.33 ? 1 GLU L N 1 ATOM 4231 C CA . GLU B 2 1 ? -155.426 -178.597 221.659 1.00 86.84 ? 1 GLU L CA 1 ATOM 4232 C C . GLU B 2 1 ? -153.942 -178.826 221.884 1.00 85.24 ? 1 GLU L C 1 ATOM 4233 O O . GLU B 2 1 ? -153.469 -179.963 221.825 1.00 81.28 ? 1 GLU L O 1 ATOM 4234 C CB . GLU B 2 1 ? -156.235 -179.223 222.793 1.00 82.61 ? 1 GLU L CB 1 ATOM 4235 C CG . GLU B 2 1 ? -155.757 -178.828 224.175 1.00 85.12 ? 1 GLU L CG 1 ATOM 4236 C CD . GLU B 2 1 ? -156.393 -179.669 225.270 1.00 102.88 ? 1 GLU L CD 1 ATOM 4237 O OE1 . GLU B 2 1 ? -157.082 -180.659 224.939 1.00 102.87 ? 1 GLU L OE1 1 ATOM 4238 O OE2 . GLU B 2 1 ? -156.205 -179.342 226.463 1.00 116.12 ? 1 GLU L OE2 1 ATOM 4239 N N . ASN B 2 2 ? -153.221 -177.738 222.151 1.00 81.08 ? 2 ASN L N 1 ATOM 4240 C CA . ASN B 2 2 ? -151.767 -177.763 222.194 1.00 71.44 ? 2 ASN L CA 1 ATOM 4241 C C . ASN B 2 2 ? -151.265 -178.221 223.559 1.00 75.31 ? 2 ASN L C 1 ATOM 4242 O O . ASN B 2 2 ? -151.072 -177.417 224.471 1.00 74.56 ? 2 ASN L O 1 ATOM 4243 C CB . ASN B 2 2 ? -151.206 -176.380 221.853 1.00 70.07 ? 2 ASN L CB 1 ATOM 4244 C CG . ASN B 2 2 ? -149.738 -176.417 221.502 1.00 77.27 ? 2 ASN L CG 1 ATOM 4245 O OD1 . ASN B 2 2 ? -149.044 -177.394 221.797 1.00 80.74 ? 2 ASN L OD1 1 ATOM 4246 N ND2 . ASN B 2 2 ? -149.252 -175.354 220.858 1.00 73.06 ? 2 ASN L ND2 1 ATOM 4247 N N . VAL B 2 3 ? -151.043 -179.521 223.700 1.00 72.61 ? 3 VAL L N 1 ATOM 4248 C CA . VAL B 2 3 ? -150.514 -180.052 224.942 1.00 68.68 ? 3 VAL L CA 1 ATOM 4249 C C . VAL B 2 3 ? -149.093 -179.549 225.212 1.00 71.02 ? 3 VAL L C 1 ATOM 4250 O O . VAL B 2 3 ? -148.246 -179.561 224.319 1.00 72.92 ? 3 VAL L O 1 ATOM 4251 C CB . VAL B 2 3 ? -150.528 -181.577 224.919 1.00 61.16 ? 3 VAL L CB 1 ATOM 4252 C CG1 . VAL B 2 3 ? -149.573 -182.130 225.948 1.00 60.90 ? 3 VAL L CG1 1 ATOM 4253 C CG2 . VAL B 2 3 ? -151.919 -182.074 225.169 1.00 59.26 ? 3 VAL L CG2 1 ATOM 4254 N N . LEU B 2 4 ? -148.843 -179.126 226.453 1.00 68.28 ? 4 LEU L N 1 ATOM 4255 C CA . LEU B 2 4 ? -147.517 -178.705 226.901 1.00 65.35 ? 4 LEU L CA 1 ATOM 4256 C C . LEU B 2 4 ? -147.038 -179.663 227.971 1.00 68.75 ? 4 LEU L C 1 ATOM 4257 O O . LEU B 2 4 ? -147.644 -179.767 229.044 1.00 67.03 ? 4 LEU L O 1 ATOM 4258 C CB . LEU B 2 4 ? -147.526 -177.271 227.450 1.00 65.84 ? 4 LEU L CB 1 ATOM 4259 C CG . LEU B 2 4 ? -148.124 -176.166 226.576 1.00 66.44 ? 4 LEU L CG 1 ATOM 4260 C CD1 . LEU B 2 4 ? -147.890 -174.816 227.189 1.00 69.39 ? 4 LEU L CD1 1 ATOM 4261 C CD2 . LEU B 2 4 ? -147.590 -176.197 225.176 1.00 66.92 ? 4 LEU L CD2 1 ATOM 4262 N N . THR B 2 5 ? -145.964 -180.384 227.669 1.00 68.34 ? 5 THR L N 1 ATOM 4263 C CA . THR B 2 5 ? -145.413 -181.349 228.599 1.00 67.14 ? 5 THR L CA 1 ATOM 4264 C C . THR B 2 5 ? -144.139 -180.787 229.208 1.00 73.22 ? 5 THR L C 1 ATOM 4265 O O . THR B 2 5 ? -143.265 -180.296 228.490 1.00 76.01 ? 5 THR L O 1 ATOM 4266 C CB . THR B 2 5 ? -145.128 -182.693 227.907 1.00 62.23 ? 5 THR L CB 1 ATOM 4267 O OG1 . THR B 2 5 ? -146.355 -183.232 227.401 1.00 74.19 ? 5 THR L OG1 1 ATOM 4268 C CG2 . THR B 2 5 ? -144.540 -183.679 228.883 1.00 57.95 ? 5 THR L CG2 1 ATOM 4269 N N . GLN B 2 6 ? -144.035 -180.850 230.534 1.00 70.22 ? 6 GLN L N 1 ATOM 4270 C CA . GLN B 2 6 ? -142.872 -180.311 231.216 1.00 67.36 ? 6 GLN L CA 1 ATOM 4271 C C . GLN B 2 6 ? -142.100 -181.403 231.920 1.00 68.49 ? 6 GLN L C 1 ATOM 4272 O O . GLN B 2 6 ? -142.684 -182.313 232.501 1.00 73.91 ? 6 GLN L O 1 ATOM 4273 C CB . GLN B 2 6 ? -143.278 -179.242 232.232 1.00 68.81 ? 6 GLN L CB 1 ATOM 4274 C CG . GLN B 2 6 ? -143.824 -177.958 231.639 1.00 71.10 ? 6 GLN L CG 1 ATOM 4275 C CD . GLN B 2 6 ? -144.367 -177.048 232.703 1.00 66.72 ? 6 GLN L CD 1 ATOM 4276 O OE1 . GLN B 2 6 ? -145.324 -177.387 233.377 1.00 71.80 ? 6 GLN L OE1 1 ATOM 4277 N NE2 . GLN B 2 6 ? -143.748 -175.898 232.876 1.00 72.23 ? 6 GLN L NE2 1 ATOM 4278 N N . SER B 2 7 ? -140.779 -181.307 231.854 1.00 70.87 ? 7 SER L N 1 ATOM 4279 C CA . SER B 2 7 ? -139.903 -182.189 232.603 1.00 71.90 ? 7 SER L CA 1 ATOM 4280 C C . SER B 2 7 ? -138.757 -181.383 233.171 1.00 68.64 ? 7 SER L C 1 ATOM 4281 O O . SER B 2 7 ? -138.403 -180.341 232.620 1.00 70.82 ? 7 SER L O 1 ATOM 4282 C CB . SER B 2 7 ? -139.389 -183.319 231.714 1.00 68.92 ? 7 SER L CB 1 ATOM 4283 O OG . SER B 2 7 ? -138.488 -182.800 230.765 1.00 82.09 ? 7 SER L OG 1 ATOM 4284 N N . PRO B 2 8 ? -138.181 -181.852 234.281 1.00 61.53 ? 8 PRO L N 1 ATOM 4285 C CA . PRO B 2 8 ? -138.676 -183.025 235.006 1.00 71.44 ? 8 PRO L CA 1 ATOM 4286 C C . PRO B 2 8 ? -140.018 -182.737 235.664 1.00 71.51 ? 8 PRO L C 1 ATOM 4287 O O . PRO B 2 8 ? -140.478 -181.602 235.594 1.00 71.81 ? 8 PRO L O 1 ATOM 4288 C CB . PRO B 2 8 ? -137.591 -183.276 236.054 1.00 70.44 ? 8 PRO L CB 1 ATOM 4289 C CG . PRO B 2 8 ? -136.871 -181.987 236.187 1.00 73.12 ? 8 PRO L CG 1 ATOM 4290 C CD . PRO B 2 8 ? -136.901 -181.374 234.821 1.00 65.74 ? 8 PRO L CD 1 ATOM 4291 N N . ALA B 2 9 ? -140.656 -183.755 236.235 1.00 72.57 ? 9 ALA L N 1 ATOM 4292 C CA . ALA B 2 9 ? -141.914 -183.568 236.960 1.00 70.59 ? 9 ALA L CA 1 ATOM 4293 C C . ALA B 2 9 ? -141.678 -183.059 238.375 1.00 72.17 ? 9 ALA L C 1 ATOM 4294 O O . ALA B 2 9 ? -142.434 -182.218 238.883 1.00 69.27 ? 9 ALA L O 1 ATOM 4295 C CB . ALA B 2 9 ? -142.692 -184.862 237.003 1.00 70.69 ? 9 ALA L CB 1 ATOM 4296 N N . ILE B 2 10 ? -140.638 -183.609 239.006 1.00 72.38 ? 10 ILE L N 1 ATOM 4297 C CA . ILE B 2 10 ? -140.179 -183.176 240.317 1.00 67.53 ? 10 ILE L CA 1 ATOM 4298 C C . ILE B 2 10 ? -138.661 -183.066 240.276 1.00 76.22 ? 10 ILE L C 1 ATOM 4299 O O . ILE B 2 10 ? -137.985 -183.774 239.529 1.00 77.30 ? 10 ILE L O 1 ATOM 4300 C CB . ILE B 2 10 ? -140.591 -184.127 241.442 1.00 64.59 ? 10 ILE L CB 1 ATOM 4301 C CG1 . ILE B 2 10 ? -142.046 -184.556 241.282 1.00 69.08 ? 10 ILE L CG1 1 ATOM 4302 C CG2 . ILE B 2 10 ? -140.403 -183.444 242.795 1.00 70.21 ? 10 ILE L CG2 1 ATOM 4303 C CD1 . ILE B 2 10 ? -142.627 -185.205 242.519 1.00 55.66 ? 10 ILE L CD1 1 ATOM 4304 N N . MET B 2 11 ? -138.122 -182.166 241.081 1.00 71.35 ? 11 MET L N 1 ATOM 4305 C CA . MET B 2 11 ? -136.754 -181.748 240.894 1.00 65.92 ? 11 MET L CA 1 ATOM 4306 C C . MET B 2 11 ? -136.209 -181.261 242.214 1.00 73.09 ? 11 MET L C 1 ATOM 4307 O O . MET B 2 11 ? -136.807 -180.401 242.855 1.00 78.93 ? 11 MET L O 1 ATOM 4308 C CB . MET B 2 11 ? -136.715 -180.663 239.831 1.00 73.38 ? 11 MET L CB 1 ATOM 4309 C CG . MET B 2 11 ? -135.368 -180.114 239.515 1.00 80.19 ? 11 MET L CG 1 ATOM 4310 S SD . MET B 2 11 ? -135.554 -179.075 238.067 1.00 76.16 ? 11 MET L SD 1 ATOM 4311 C CE . MET B 2 11 ? -133.864 -178.511 237.889 1.00 85.78 ? 11 MET L CE 1 ATOM 4312 N N . SER B 2 12 ? -135.102 -181.842 242.654 1.00 73.00 ? 12 SER L N 1 ATOM 4313 C CA . SER B 2 12 ? -134.532 -181.467 243.940 1.00 71.22 ? 12 SER L CA 1 ATOM 4314 C C . SER B 2 12 ? -133.210 -180.786 243.665 1.00 77.67 ? 12 SER L C 1 ATOM 4315 O O . SER B 2 12 ? -132.482 -181.183 242.756 1.00 81.35 ? 12 SER L O 1 ATOM 4316 C CB . SER B 2 12 ? -134.342 -182.681 244.855 1.00 77.79 ? 12 SER L CB 1 ATOM 4317 O OG . SER B 2 12 ? -135.532 -183.459 244.964 1.00 83.06 ? 12 SER L OG 1 ATOM 4318 N N . THR B 2 13 ? -132.897 -179.747 244.424 1.00 83.18 ? 13 THR L N 1 ATOM 4319 C CA . THR B 2 13 ? -131.687 -178.996 244.147 1.00 82.10 ? 13 THR L CA 1 ATOM 4320 C C . THR B 2 13 ? -131.150 -178.344 245.404 1.00 77.39 ? 13 THR L C 1 ATOM 4321 O O . THR B 2 13 ? -131.911 -177.893 246.256 1.00 78.34 ? 13 THR L O 1 ATOM 4322 C CB . THR B 2 13 ? -131.943 -177.943 243.067 1.00 80.08 ? 13 THR L CB 1 ATOM 4323 O OG1 . THR B 2 13 ? -132.354 -178.610 241.869 1.00 89.67 ? 13 THR L OG1 1 ATOM 4324 C CG2 . THR B 2 13 ? -130.683 -177.158 242.771 1.00 79.32 ? 13 THR L CG2 1 ATOM 4325 N N . SER B 2 14 ? -129.828 -178.348 245.524 1.00 78.93 ? 14 SER L N 1 ATOM 4326 C CA . SER B 2 14 ? -129.152 -177.673 246.618 1.00 81.22 ? 14 SER L CA 1 ATOM 4327 C C . SER B 2 14 ? -129.135 -176.178 246.349 1.00 74.42 ? 14 SER L C 1 ATOM 4328 O O . SER B 2 14 ? -128.943 -175.764 245.206 1.00 75.64 ? 14 SER L O 1 ATOM 4329 C CB . SER B 2 14 ? -127.725 -178.204 246.777 1.00 86.97 ? 14 SER L CB 1 ATOM 4330 O OG . SER B 2 14 ? -127.675 -179.607 246.553 1.00 90.94 ? 14 SER L OG 1 ATOM 4331 N N . PRO B 2 15 ? -129.311 -175.360 247.396 1.00 75.58 ? 15 PRO L N 1 ATOM 4332 C CA . PRO B 2 15 ? -129.256 -173.918 247.127 1.00 73.91 ? 15 PRO L CA 1 ATOM 4333 C C . PRO B 2 15 ? -127.900 -173.534 246.550 1.00 70.09 ? 15 PRO L C 1 ATOM 4334 O O . PRO B 2 15 ? -126.883 -174.088 246.965 1.00 76.61 ? 15 PRO L O 1 ATOM 4335 C CB . PRO B 2 15 ? -129.451 -173.298 248.510 1.00 59.19 ? 15 PRO L CB 1 ATOM 4336 C CG . PRO B 2 15 ? -130.292 -174.293 249.236 1.00 70.91 ? 15 PRO L CG 1 ATOM 4337 C CD . PRO B 2 15 ? -129.845 -175.656 248.738 1.00 72.71 ? 15 PRO L CD 1 ATOM 4338 N N . GLY B 2 16 ? -127.899 -172.616 245.594 1.00 69.80 ? 16 GLY L N 1 ATOM 4339 C CA . GLY B 2 16 ? -126.702 -172.247 244.863 1.00 66.14 ? 16 GLY L CA 1 ATOM 4340 C C . GLY B 2 16 ? -126.498 -172.994 243.551 1.00 74.79 ? 16 GLY L C 1 ATOM 4341 O O . GLY B 2 16 ? -125.795 -172.504 242.666 1.00 77.68 ? 16 GLY L O 1 ATOM 4342 N N . GLU B 2 17 ? -127.099 -174.173 243.406 1.00 74.55 ? 17 GLU L N 1 ATOM 4343 C CA . GLU B 2 17 ? -126.965 -174.927 242.155 1.00 77.82 ? 17 GLU L CA 1 ATOM 4344 C C . GLU B 2 17 ? -127.742 -174.300 240.998 1.00 78.46 ? 17 GLU L C 1 ATOM 4345 O O . GLU B 2 17 ? -128.699 -173.569 241.209 1.00 81.53 ? 17 GLU L O 1 ATOM 4346 C CB . GLU B 2 17 ? -127.425 -176.372 242.336 1.00 78.54 ? 17 GLU L CB 1 ATOM 4347 C CG . GLU B 2 17 ? -126.401 -177.280 242.997 1.00 83.77 ? 17 GLU L CG 1 ATOM 4348 C CD . GLU B 2 17 ? -126.831 -178.744 243.010 1.00 99.30 ? 17 GLU L CD 1 ATOM 4349 O OE1 . GLU B 2 17 ? -127.971 -179.051 242.572 1.00 99.27 ? 17 GLU L OE1 1 ATOM 4350 O OE2 . GLU B 2 17 ? -126.018 -179.589 243.457 1.00 107.64 ? 17 GLU L OE2 1 ATOM 4351 N N . LYS B 2 18 ? -127.285 -174.525 239.775 1.00 80.02 ? 18 LYS L N 1 ATOM 4352 C CA . LYS B 2 18 ? -128.083 -174.172 238.604 1.00 81.99 ? 18 LYS L CA 1 ATOM 4353 C C . LYS B 2 18 ? -129.254 -175.152 238.442 1.00 81.62 ? 18 LYS L C 1 ATOM 4354 O O . LYS B 2 18 ? -129.099 -176.341 238.711 1.00 85.45 ? 18 LYS L O 1 ATOM 4355 C CB . LYS B 2 18 ? -127.213 -174.155 237.346 1.00 81.42 ? 18 LYS L CB 1 ATOM 4356 C CG . LYS B 2 18 ? -127.917 -173.608 236.117 1.00 87.00 ? 18 LYS L CG 1 ATOM 4357 C CD . LYS B 2 18 ? -126.962 -173.330 234.952 1.00 93.16 ? 18 LYS L CD 1 ATOM 4358 C CE . LYS B 2 18 ? -126.751 -174.573 234.085 1.00 108.76 ? 18 LYS L CE 1 ATOM 4359 N NZ . LYS B 2 18 ? -125.717 -174.345 233.025 1.00 114.22 ? 18 LYS L NZ 1 ATOM 4360 N N . VAL B 2 19 ? -130.417 -174.672 238.002 1.00 78.59 ? 19 VAL L N 1 ATOM 4361 C CA . VAL B 2 19 ? -131.516 -175.572 237.657 1.00 74.04 ? 19 VAL L CA 1 ATOM 4362 C C . VAL B 2 19 ? -132.111 -175.179 236.323 1.00 75.21 ? 19 VAL L C 1 ATOM 4363 O O . VAL B 2 19 ? -132.289 -173.993 236.030 1.00 75.41 ? 19 VAL L O 1 ATOM 4364 C CB . VAL B 2 19 ? -132.652 -175.580 238.708 1.00 75.37 ? 19 VAL L CB 1 ATOM 4365 C CG1 . VAL B 2 19 ? -132.106 -175.764 240.100 1.00 78.94 ? 19 VAL L CG1 1 ATOM 4366 C CG2 . VAL B 2 19 ? -133.468 -174.322 238.624 1.00 77.64 ? 19 VAL L CG2 1 ATOM 4367 N N . THR B 2 20 ? -132.412 -176.187 235.512 1.00 77.86 ? 20 THR L N 1 ATOM 4368 C CA . THR B 2 20 ? -133.110 -175.973 234.254 1.00 73.15 ? 20 THR L CA 1 ATOM 4369 C C . THR B 2 20 ? -134.319 -176.874 234.218 1.00 72.82 ? 20 THR L C 1 ATOM 4370 O O . THR B 2 20 ? -134.332 -177.951 234.822 1.00 69.97 ? 20 THR L O 1 ATOM 4371 C CB . THR B 2 20 ? -132.238 -176.262 233.024 1.00 69.84 ? 20 THR L CB 1 ATOM 4372 O OG1 . THR B 2 20 ? -131.122 -175.370 233.007 1.00 88.06 ? 20 THR L OG1 1 ATOM 4373 C CG2 . THR B 2 20 ? -133.030 -176.047 231.762 1.00 69.17 ? 20 THR L CG2 1 ATOM 4374 N N . MET B 2 21 ? -135.340 -176.409 233.517 1.00 71.35 ? 21 MET L N 1 ATOM 4375 C CA . MET B 2 21 ? -136.563 -177.161 233.348 1.00 69.61 ? 21 MET L CA 1 ATOM 4376 C C . MET B 2 21 ? -137.136 -176.808 231.992 1.00 70.64 ? 21 MET L C 1 ATOM 4377 O O . MET B 2 21 ? -137.018 -175.667 231.539 1.00 72.08 ? 21 MET L O 1 ATOM 4378 C CB . MET B 2 21 ? -137.547 -176.849 234.468 1.00 71.36 ? 21 MET L CB 1 ATOM 4379 C CG . MET B 2 21 ? -137.917 -175.384 234.575 1.00 67.10 ? 21 MET L CG 1 ATOM 4380 S SD . MET B 2 21 ? -138.935 -175.127 236.027 1.00 72.50 ? 21 MET L SD 1 ATOM 4381 C CE . MET B 2 21 ? -137.694 -174.791 237.268 1.00 65.07 ? 21 MET L CE 1 ATOM 4382 N N . THR B 2 22 ? -137.760 -177.783 231.344 1.00 69.45 ? 22 THR L N 1 ATOM 4383 C CA . THR B 2 22 ? -138.145 -177.609 229.953 1.00 69.65 ? 22 THR L CA 1 ATOM 4384 C C . THR B 2 22 ? -139.652 -177.731 229.723 1.00 71.08 ? 22 THR L C 1 ATOM 4385 O O . THR B 2 22 ? -140.380 -178.295 230.544 1.00 66.75 ? 22 THR L O 1 ATOM 4386 C CB . THR B 2 22 ? -137.408 -178.622 229.056 1.00 71.13 ? 22 THR L CB 1 ATOM 4387 O OG1 . THR B 2 22 ? -137.561 -179.940 229.596 1.00 73.56 ? 22 THR L OG1 1 ATOM 4388 C CG2 . THR B 2 22 ? -135.931 -178.288 228.984 1.00 68.30 ? 22 THR L CG2 1 ATOM 4389 N N . CYS B 2 23 ? -140.097 -177.180 228.593 1.00 73.73 ? 23 CYS L N 1 ATOM 4390 C CA . CYS B 2 23 ? -141.502 -177.185 228.183 1.00 75.53 ? 23 CYS L CA 1 ATOM 4391 C C . CYS B 2 23 ? -141.586 -177.628 226.727 1.00 74.21 ? 23 CYS L C 1 ATOM 4392 O O . CYS B 2 23 ? -140.992 -176.993 225.866 1.00 82.05 ? 23 CYS L O 1 ATOM 4393 C CB . CYS B 2 23 ? -142.105 -175.787 228.342 1.00 76.19 ? 23 CYS L CB 1 ATOM 4394 S SG . CYS B 2 23 ? -143.900 -175.626 228.137 1.00 84.94 ? 23 CYS L SG 1 ATOM 4395 N N . ARG B 2 24 ? -142.296 -178.711 226.436 1.00 75.01 ? 24 ARG L N 1 ATOM 4396 C CA . ARG B 2 24 ? -142.439 -179.136 225.047 1.00 73.02 ? 24 ARG L CA 1 ATOM 4397 C C . ARG B 2 24 ? -143.885 -179.128 224.591 1.00 72.60 ? 24 ARG L C 1 ATOM 4398 O O . ARG B 2 24 ? -144.738 -179.781 225.180 1.00 73.25 ? 24 ARG L O 1 ATOM 4399 C CB . ARG B 2 24 ? -141.823 -180.518 224.848 1.00 73.51 ? 24 ARG L CB 1 ATOM 4400 C CG . ARG B 2 24 ? -140.318 -180.460 224.967 1.00 85.75 ? 24 ARG L CG 1 ATOM 4401 C CD . ARG B 2 24 ? -139.580 -181.770 224.700 1.00 92.80 ? 24 ARG L CD 1 ATOM 4402 N NE . ARG B 2 24 ? -138.156 -181.583 224.996 1.00 102.30 ? 24 ARG L NE 1 ATOM 4403 C CZ . ARG B 2 24 ? -137.289 -180.968 224.188 1.00 97.30 ? 24 ARG L CZ 1 ATOM 4404 N NH1 . ARG B 2 24 ? -137.686 -180.489 223.015 1.00 89.39 ? 24 ARG L NH1 1 ATOM 4405 N NH2 . ARG B 2 24 ? -136.020 -180.836 224.554 1.00 98.99 ? 24 ARG L NH2 1 ATOM 4406 N N . ALA B 2 25 ? -144.151 -178.357 223.543 1.00 74.04 ? 25 ALA L N 1 ATOM 4407 C CA . ALA B 2 25 ? -145.491 -178.263 222.984 1.00 72.31 ? 25 ALA L CA 1 ATOM 4408 C C . ALA B 2 25 ? -145.683 -179.264 221.858 1.00 74.54 ? 25 ALA L C 1 ATOM 4409 O O . ALA B 2 25 ? -144.738 -179.591 221.137 1.00 73.54 ? 25 ALA L O 1 ATOM 4410 C CB . ALA B 2 25 ? -145.759 -176.857 222.493 1.00 73.09 ? 25 ALA L CB 1 ATOM 4411 N N . SER B 2 26 ? -146.915 -179.736 221.703 1.00 74.49 ? 26 SER L N 1 ATOM 4412 C CA . SER B 2 26 ? -147.251 -180.658 220.629 1.00 72.65 ? 26 SER L CA 1 ATOM 4413 C C . SER B 2 26 ? -147.433 -179.900 219.317 1.00 81.11 ? 26 SER L C 1 ATOM 4414 O O . SER B 2 26 ? -147.582 -180.498 218.256 1.00 90.23 ? 26 SER L O 1 ATOM 4415 C CB . SER B 2 26 ? -148.512 -181.437 220.965 1.00 73.16 ? 26 SER L CB 1 ATOM 4416 O OG . SER B 2 26 ? -149.599 -180.561 221.200 1.00 84.24 ? 26 SER L OG 1 ATOM 4417 N N . SER B 2 27 ? -147.423 -178.576 219.398 1.00 77.69 ? 27 SER L N 1 ATOM 4418 C CA . SER B 2 27 ? -147.541 -177.732 218.220 1.00 77.62 ? 27 SER L CA 1 ATOM 4419 C C . SER B 2 27 ? -146.665 -176.513 218.416 1.00 78.95 ? 27 SER L C 1 ATOM 4420 O O . SER B 2 27 ? -146.341 -176.152 219.537 1.00 81.96 ? 27 SER L O 1 ATOM 4421 C CB . SER B 2 27 ? -148.990 -177.305 217.988 1.00 77.53 ? 27 SER L CB 1 ATOM 4422 O OG . SER B 2 27 ? -149.880 -178.397 218.167 1.00 90.75 ? 27 SER L OG 1 ATOM 4423 N N . SER B 2 28 ? -146.277 -175.865 217.334 1.00 80.08 ? 28 SER L N 1 ATOM 4424 C CA . SER B 2 28 ? -145.435 -174.699 217.476 1.00 76.91 ? 28 SER L CA 1 ATOM 4425 C C . SER B 2 28 ? -146.163 -173.596 218.249 1.00 81.18 ? 28 SER L C 1 ATOM 4426 O O . SER B 2 28 ? -147.372 -173.400 218.102 1.00 86.63 ? 28 SER L O 1 ATOM 4427 C CB . SER B 2 28 ? -144.992 -174.192 216.107 1.00 78.93 ? 28 SER L CB 1 ATOM 4428 O OG . SER B 2 28 ? -144.082 -173.116 216.255 1.00 85.13 ? 28 SER L OG 1 ATOM 4429 N N . VAL B 2 29 ? -145.420 -172.884 219.085 1.00 77.18 ? 29 VAL L N 1 ATOM 4430 C CA . VAL B 2 29 ? -145.953 -171.725 219.787 1.00 75.70 ? 29 VAL L CA 1 ATOM 4431 C C . VAL B 2 29 ? -145.061 -170.520 219.507 1.00 77.38 ? 29 VAL L C 1 ATOM 4432 O O . VAL B 2 29 ? -143.834 -170.606 219.639 1.00 75.72 ? 29 VAL L O 1 ATOM 4433 C CB . VAL B 2 29 ? -146.029 -171.969 221.307 1.00 74.71 ? 29 VAL L CB 1 ATOM 4434 C CG1 . VAL B 2 29 ? -146.324 -170.675 222.037 1.00 73.61 ? 29 VAL L CG1 1 ATOM 4435 C CG2 . VAL B 2 29 ? -147.074 -173.024 221.627 1.00 78.31 ? 29 VAL L CG2 1 ATOM 4436 N N . GLY B 2 30 ? -145.663 -169.403 219.110 1.00 69.42 ? 30 GLY L N 1 ATOM 4437 C CA . GLY B 2 30 ? -144.896 -168.185 218.914 1.00 67.40 ? 30 GLY L CA 1 ATOM 4438 C C . GLY B 2 30 ? -144.238 -167.784 220.224 1.00 71.30 ? 30 GLY L C 1 ATOM 4439 O O . GLY B 2 30 ? -144.841 -167.887 221.292 1.00 73.04 ? 30 GLY L O 1 ATOM 4440 N N . SER B 2 31 ? -142.996 -167.337 220.165 1.00 70.49 ? 31 SER L N 1 ATOM 4441 C CA . SER B 2 31 ? -142.250 -167.108 221.396 1.00 73.02 ? 31 SER L CA 1 ATOM 4442 C C . SER B 2 31 ? -142.796 -165.921 222.175 1.00 73.38 ? 31 SER L C 1 ATOM 4443 O O . SER B 2 31 ? -142.533 -165.772 223.373 1.00 72.48 ? 31 SER L O 1 ATOM 4444 C CB . SER B 2 31 ? -140.771 -166.898 221.102 1.00 71.90 ? 31 SER L CB 1 ATOM 4445 O OG . SER B 2 31 ? -140.585 -165.739 220.309 1.00 85.80 ? 31 SER L OG 1 ATOM 4446 N N . SER B 2 32 ? -143.548 -165.059 221.509 1.00 70.55 ? 32 SER L N 1 ATOM 4447 C CA . SER B 2 32 ? -144.130 -163.943 222.236 1.00 75.16 ? 32 SER L CA 1 ATOM 4448 C C . SER B 2 32 ? -145.362 -164.424 223.006 1.00 76.75 ? 32 SER L C 1 ATOM 4449 O O . SER B 2 32 ? -145.936 -163.676 223.793 1.00 79.53 ? 32 SER L O 1 ATOM 4450 C CB . SER B 2 32 ? -144.497 -162.798 221.294 1.00 74.65 ? 32 SER L CB 1 ATOM 4451 O OG . SER B 2 32 ? -145.514 -163.203 220.398 1.00 81.65 ? 32 SER L OG 1 ATOM 4452 N N . TYR B 2 33 ? -145.765 -165.674 222.770 1.00 72.19 ? 33 TYR L N 1 ATOM 4453 C CA . TYR B 2 33 ? -146.942 -166.249 223.413 1.00 67.71 ? 33 TYR L CA 1 ATOM 4454 C C . TYR B 2 33 ? -146.633 -167.292 224.503 1.00 74.87 ? 33 TYR L C 1 ATOM 4455 O O . TYR B 2 33 ? -147.551 -167.926 225.041 1.00 74.27 ? 33 TYR L O 1 ATOM 4456 C CB . TYR B 2 33 ? -147.849 -166.880 222.354 1.00 73.21 ? 33 TYR L CB 1 ATOM 4457 C CG . TYR B 2 33 ? -148.498 -165.865 221.429 1.00 79.84 ? 33 TYR L CG 1 ATOM 4458 C CD1 . TYR B 2 33 ? -149.674 -165.210 221.790 1.00 77.33 ? 33 TYR L CD1 1 ATOM 4459 C CD2 . TYR B 2 33 ? -147.929 -165.550 220.192 1.00 75.06 ? 33 TYR L CD2 1 ATOM 4460 C CE1 . TYR B 2 33 ? -150.255 -164.282 220.939 1.00 79.74 ? 33 TYR L CE1 1 ATOM 4461 C CE2 . TYR B 2 33 ? -148.515 -164.623 219.348 1.00 70.52 ? 33 TYR L CE2 1 ATOM 4462 C CZ . TYR B 2 33 ? -149.668 -163.997 219.722 1.00 73.89 ? 33 TYR L CZ 1 ATOM 4463 O OH . TYR B 2 33 ? -150.250 -163.082 218.876 1.00 80.44 ? 33 TYR L OH 1 ATOM 4464 N N . LEU B 2 34 ? -145.360 -167.505 224.819 1.00 69.02 ? 34 LEU L N 1 ATOM 4465 C CA . LEU B 2 34 ? -145.040 -168.483 225.844 1.00 67.29 ? 34 LEU L CA 1 ATOM 4466 C C . LEU B 2 34 ? -144.734 -167.824 227.175 1.00 69.41 ? 34 LEU L C 1 ATOM 4467 O O . LEU B 2 34 ? -143.939 -166.891 227.235 1.00 72.91 ? 34 LEU L O 1 ATOM 4468 C CB . LEU B 2 34 ? -143.865 -169.352 225.423 1.00 67.66 ? 34 LEU L CB 1 ATOM 4469 C CG . LEU B 2 34 ? -143.840 -170.518 226.416 1.00 68.13 ? 34 LEU L CG 1 ATOM 4470 C CD1 . LEU B 2 34 ? -144.310 -171.804 225.784 1.00 58.86 ? 34 LEU L CD1 1 ATOM 4471 C CD2 . LEU B 2 34 ? -142.503 -170.667 227.085 1.00 69.26 ? 34 LEU L CD2 1 ATOM 4472 N N . HIS B 2 35 ? -145.336 -168.325 228.249 1.00 63.69 ? 35 HIS L N 1 ATOM 4473 C CA . HIS B 2 35 ? -145.176 -167.690 229.555 1.00 67.25 ? 35 HIS L CA 1 ATOM 4474 C C . HIS B 2 35 ? -144.936 -168.728 230.634 1.00 67.17 ? 35 HIS L C 1 ATOM 4475 O O . HIS B 2 35 ? -145.174 -169.908 230.426 1.00 69.41 ? 35 HIS L O 1 ATOM 4476 C CB . HIS B 2 35 ? -146.411 -166.845 229.895 1.00 64.88 ? 35 HIS L CB 1 ATOM 4477 C CG . HIS B 2 35 ? -146.919 -166.031 228.741 1.00 70.88 ? 35 HIS L CG 1 ATOM 4478 N ND1 . HIS B 2 35 ? -146.163 -165.055 228.127 1.00 71.36 ? 35 HIS L ND1 1 ATOM 4479 C CD2 . HIS B 2 35 ? -148.097 -166.064 228.073 1.00 72.24 ? 35 HIS L CD2 1 ATOM 4480 C CE1 . HIS B 2 35 ? -146.857 -164.516 227.139 1.00 70.07 ? 35 HIS L CE1 1 ATOM 4481 N NE2 . HIS B 2 35 ? -148.035 -165.110 227.084 1.00 68.16 ? 35 HIS L NE2 1 ATOM 4482 N N . TRP B 2 36 ? -144.471 -168.286 231.793 1.00 65.38 ? 36 TRP L N 1 ATOM 4483 C CA . TRP B 2 36 ? -144.254 -169.195 232.906 1.00 65.68 ? 36 TRP L CA 1 ATOM 4484 C C . TRP B 2 36 ? -144.884 -168.627 234.164 1.00 67.80 ? 36 TRP L C 1 ATOM 4485 O O . TRP B 2 36 ? -144.865 -167.417 234.378 1.00 68.61 ? 36 TRP L O 1 ATOM 4486 C CB . TRP B 2 36 ? -142.768 -169.417 233.152 1.00 66.94 ? 36 TRP L CB 1 ATOM 4487 C CG . TRP B 2 36 ? -142.053 -170.105 232.036 1.00 69.84 ? 36 TRP L CG 1 ATOM 4488 C CD1 . TRP B 2 36 ? -141.614 -169.547 230.887 1.00 68.04 ? 36 TRP L CD1 1 ATOM 4489 C CD2 . TRP B 2 36 ? -141.682 -171.488 231.983 1.00 70.35 ? 36 TRP L CD2 1 ATOM 4490 N NE1 . TRP B 2 36 ? -140.993 -170.495 230.107 1.00 67.69 ? 36 TRP L NE1 1 ATOM 4491 C CE2 . TRP B 2 36 ? -141.017 -171.693 230.763 1.00 64.00 ? 36 TRP L CE2 1 ATOM 4492 C CE3 . TRP B 2 36 ? -141.856 -172.571 232.847 1.00 62.93 ? 36 TRP L CE3 1 ATOM 4493 C CZ2 . TRP B 2 36 ? -140.518 -172.931 230.386 1.00 65.86 ? 36 TRP L CZ2 1 ATOM 4494 C CZ3 . TRP B 2 36 ? -141.368 -173.797 232.469 1.00 67.71 ? 36 TRP L CZ3 1 ATOM 4495 C CH2 . TRP B 2 36 ? -140.705 -173.971 231.245 1.00 67.69 ? 36 TRP L CH2 1 ATOM 4496 N N . TYR B 2 37 ? -145.414 -169.497 235.012 1.00 66.67 ? 37 TYR L N 1 ATOM 4497 C CA . TYR B 2 37 ? -145.904 -169.065 236.302 1.00 61.95 ? 37 TYR L CA 1 ATOM 4498 C C . TYR B 2 37 ? -145.278 -169.877 237.418 1.00 62.99 ? 37 TYR L C 1 ATOM 4499 O O . TYR B 2 37 ? -145.056 -171.077 237.268 1.00 66.18 ? 37 TYR L O 1 ATOM 4500 C CB . TYR B 2 37 ? -147.417 -169.194 236.357 1.00 66.10 ? 37 TYR L CB 1 ATOM 4501 C CG . TYR B 2 37 ? -148.135 -168.567 235.189 1.00 62.94 ? 37 TYR L CG 1 ATOM 4502 C CD1 . TYR B 2 37 ? -148.713 -167.315 235.296 1.00 63.46 ? 37 TYR L CD1 1 ATOM 4503 C CD2 . TYR B 2 37 ? -148.254 -169.234 233.990 1.00 64.71 ? 37 TYR L CD2 1 ATOM 4504 C CE1 . TYR B 2 37 ? -149.381 -166.737 234.222 1.00 64.58 ? 37 TYR L CE1 1 ATOM 4505 C CE2 . TYR B 2 37 ? -148.925 -168.667 232.917 1.00 69.99 ? 37 TYR L CE2 1 ATOM 4506 C CZ . TYR B 2 37 ? -149.482 -167.415 233.041 1.00 64.45 ? 37 TYR L CZ 1 ATOM 4507 O OH . TYR B 2 37 ? -150.145 -166.857 231.972 1.00 67.21 ? 37 TYR L OH 1 ATOM 4508 N N . GLN B 2 38 ? -144.974 -169.223 238.533 1.00 60.70 ? 38 GLN L N 1 ATOM 4509 C CA . GLN B 2 38 ? -144.551 -169.944 239.723 1.00 63.39 ? 38 GLN L CA 1 ATOM 4510 C C . GLN B 2 38 ? -145.716 -169.980 240.676 1.00 67.92 ? 38 GLN L C 1 ATOM 4511 O O . GLN B 2 38 ? -146.448 -168.990 240.785 1.00 70.07 ? 38 GLN L O 1 ATOM 4512 C CB . GLN B 2 38 ? -143.350 -169.287 240.385 1.00 63.99 ? 38 GLN L CB 1 ATOM 4513 C CG . GLN B 2 38 ? -143.577 -168.997 241.848 1.00 69.72 ? 38 GLN L CG 1 ATOM 4514 C CD . GLN B 2 38 ? -142.358 -168.410 242.504 1.00 71.59 ? 38 GLN L CD 1 ATOM 4515 O OE1 . GLN B 2 38 ? -141.232 -168.825 242.213 1.00 65.61 ? 38 GLN L OE1 1 ATOM 4516 N NE2 . GLN B 2 38 ? -142.566 -167.428 243.387 1.00 72.84 ? 38 GLN L NE2 1 ATOM 4517 N N . GLN B 2 39 ? -145.905 -171.102 241.363 1.00 64.71 ? 39 GLN L N 1 ATOM 4518 C CA . GLN B 2 39 ? -146.987 -171.206 242.337 1.00 63.17 ? 39 GLN L CA 1 ATOM 4519 C C . GLN B 2 39 ? -146.458 -171.863 243.581 1.00 68.04 ? 39 GLN L C 1 ATOM 4520 O O . GLN B 2 39 ? -146.242 -173.071 243.587 1.00 73.86 ? 39 GLN L O 1 ATOM 4521 C CB . GLN B 2 39 ? -148.156 -172.013 241.794 1.00 63.04 ? 39 GLN L CB 1 ATOM 4522 C CG . GLN B 2 39 ? -149.214 -172.333 242.826 1.00 62.94 ? 39 GLN L CG 1 ATOM 4523 C CD . GLN B 2 39 ? -150.437 -172.998 242.221 1.00 65.40 ? 39 GLN L CD 1 ATOM 4524 O OE1 . GLN B 2 39 ? -150.316 -173.932 241.434 1.00 68.62 ? 39 GLN L OE1 1 ATOM 4525 N NE2 . GLN B 2 39 ? -151.628 -172.516 242.593 1.00 64.25 ? 39 GLN L NE2 1 ATOM 4526 N N . LYS B 2 40 ? -146.214 -171.070 244.622 1.00 71.53 ? 40 LYS L N 1 ATOM 4527 C CA . LYS B 2 40 ? -145.713 -171.604 245.885 1.00 71.41 ? 40 LYS L CA 1 ATOM 4528 C C . LYS B 2 40 ? -146.842 -172.371 246.575 1.00 71.35 ? 40 LYS L C 1 ATOM 4529 O O . LYS B 2 40 ? -148.026 -172.134 246.314 1.00 67.44 ? 40 LYS L O 1 ATOM 4530 C CB . LYS B 2 40 ? -145.133 -170.485 246.769 1.00 63.86 ? 40 LYS L CB 1 ATOM 4531 C CG . LYS B 2 40 ? -143.639 -170.248 246.470 1.00 71.16 ? 40 LYS L CG 1 ATOM 4532 C CD . LYS B 2 40 ? -143.044 -168.955 247.018 1.00 69.37 ? 40 LYS L CD 1 ATOM 4533 C CE . LYS B 2 40 ? -142.154 -169.220 248.241 1.00 78.32 ? 40 LYS L CE 1 ATOM 4534 N NZ . LYS B 2 40 ? -141.156 -170.321 248.042 1.00 78.28 ? 40 LYS L NZ 1 ATOM 4535 N N . SER B 2 41 ? -146.471 -173.333 247.411 1.00 77.93 ? 41 SER L N 1 ATOM 4536 C CA . SER B 2 41 ? -147.453 -174.219 248.024 1.00 79.82 ? 41 SER L CA 1 ATOM 4537 C C . SER B 2 41 ? -148.507 -173.455 248.825 1.00 81.30 ? 41 SER L C 1 ATOM 4538 O O . SER B 2 41 ? -148.167 -172.666 249.711 1.00 82.54 ? 41 SER L O 1 ATOM 4539 C CB . SER B 2 41 ? -146.744 -175.223 248.937 1.00 83.34 ? 41 SER L CB 1 ATOM 4540 O OG . SER B 2 41 ? -147.697 -176.006 249.638 1.00 93.99 ? 41 SER L OG 1 ATOM 4541 N N . GLY B 2 42 ? -149.781 -173.722 248.538 1.00 74.49 ? 42 GLY L N 1 ATOM 4542 C CA . GLY B 2 42 ? -150.879 -173.068 249.231 1.00 66.80 ? 42 GLY L CA 1 ATOM 4543 C C . GLY B 2 42 ? -151.242 -171.678 248.743 1.00 72.43 ? 42 GLY L C 1 ATOM 4544 O O . GLY B 2 42 ? -152.054 -170.994 249.371 1.00 78.97 ? 42 GLY L O 1 ATOM 4545 N N . ALA B 2 43 ? -150.654 -171.252 247.627 1.00 75.51 ? 43 ALA L N 1 ATOM 4546 C CA . ALA B 2 43 ? -150.893 -169.902 247.104 1.00 67.70 ? 43 ALA L CA 1 ATOM 4547 C C . ALA B 2 43 ? -151.365 -169.940 245.661 1.00 67.98 ? 43 ALA L C 1 ATOM 4548 O O . ALA B 2 43 ? -151.302 -170.985 245.010 1.00 71.81 ? 43 ALA L O 1 ATOM 4549 C CB . ALA B 2 43 ? -149.638 -169.056 247.209 1.00 63.94 ? 43 ALA L CB 1 ATOM 4550 N N . SER B 2 44 ? -151.847 -168.802 245.169 1.00 67.56 ? 44 SER L N 1 ATOM 4551 C CA . SER B 2 44 ? -152.218 -168.665 243.761 1.00 68.32 ? 44 SER L CA 1 ATOM 4552 C C . SER B 2 44 ? -150.968 -168.556 242.895 1.00 67.64 ? 44 SER L C 1 ATOM 4553 O O . SER B 2 44 ? -149.909 -168.130 243.374 1.00 67.98 ? 44 SER L O 1 ATOM 4554 C CB . SER B 2 44 ? -153.114 -167.440 243.537 1.00 66.90 ? 44 SER L CB 1 ATOM 4555 O OG . SER B 2 44 ? -153.680 -166.970 244.754 1.00 78.43 ? 44 SER L OG 1 ATOM 4556 N N . PRO B 2 45 ? -151.089 -168.926 241.616 1.00 67.56 ? 45 PRO L N 1 ATOM 4557 C CA . PRO B 2 45 ? -150.006 -168.768 240.648 1.00 64.32 ? 45 PRO L CA 1 ATOM 4558 C C . PRO B 2 45 ? -149.636 -167.300 240.498 1.00 63.79 ? 45 PRO L C 1 ATOM 4559 O O . PRO B 2 45 ? -150.494 -166.461 240.719 1.00 65.47 ? 45 PRO L O 1 ATOM 4560 C CB . PRO B 2 45 ? -150.617 -169.310 239.355 1.00 63.09 ? 45 PRO L CB 1 ATOM 4561 C CG . PRO B 2 45 ? -151.679 -170.239 239.789 1.00 62.28 ? 45 PRO L CG 1 ATOM 4562 C CD . PRO B 2 45 ? -152.246 -169.629 241.031 1.00 68.96 ? 45 PRO L CD 1 ATOM 4563 N N . LYS B 2 46 ? -148.366 -167.002 240.239 1.00 64.94 ? 46 LYS L N 1 ATOM 4564 C CA . LYS B 2 46 ? -147.959 -165.653 239.853 1.00 62.67 ? 46 LYS L CA 1 ATOM 4565 C C . LYS B 2 46 ? -147.332 -165.623 238.457 1.00 62.52 ? 46 LYS L C 1 ATOM 4566 O O . LYS B 2 46 ? -146.562 -166.506 238.121 1.00 66.15 ? 46 LYS L O 1 ATOM 4567 C CB . LYS B 2 46 ? -146.984 -165.098 240.878 1.00 58.66 ? 46 LYS L CB 1 ATOM 4568 C CG . LYS B 2 46 ? -147.571 -164.985 242.245 1.00 63.18 ? 46 LYS L CG 1 ATOM 4569 C CD . LYS B 2 46 ? -146.650 -164.251 243.204 1.00 59.25 ? 46 LYS L CD 1 ATOM 4570 C CE . LYS B 2 46 ? -147.374 -163.995 244.511 1.00 54.50 ? 46 LYS L CE 1 ATOM 4571 N NZ . LYS B 2 46 ? -146.422 -163.532 245.534 1.00 73.81 ? 46 LYS L NZ 1 ATOM 4572 N N . LEU B 2 47 ? -147.659 -164.617 237.647 1.00 67.74 ? 47 LEU L N 1 ATOM 4573 C CA . LEU B 2 47 ? -146.999 -164.476 236.356 1.00 65.12 ? 47 LEU L CA 1 ATOM 4574 C C . LEU B 2 47 ? -145.543 -164.271 236.650 1.00 65.17 ? 47 LEU L C 1 ATOM 4575 O O . LEU B 2 47 ? -145.210 -163.663 237.660 1.00 65.30 ? 47 LEU L O 1 ATOM 4576 C CB . LEU B 2 47 ? -147.538 -163.300 235.535 1.00 73.45 ? 47 LEU L CB 1 ATOM 4577 C CG . LEU B 2 47 ? -146.665 -163.004 234.308 1.00 67.00 ? 47 LEU L CG 1 ATOM 4578 C CD1 . LEU B 2 47 ? -146.863 -164.090 233.252 1.00 63.41 ? 47 LEU L CD1 1 ATOM 4579 C CD2 . LEU B 2 47 ? -146.961 -161.630 233.738 1.00 67.49 ? 47 LEU L CD2 1 ATOM 4580 N N . TRP B 2 48 ? -144.678 -164.778 235.781 1.00 65.49 ? 48 TRP L N 1 ATOM 4581 C CA . TRP B 2 48 ? -143.281 -164.965 236.158 1.00 66.28 ? 48 TRP L CA 1 ATOM 4582 C C . TRP B 2 48 ? -142.305 -164.653 235.033 1.00 68.42 ? 48 TRP L C 1 ATOM 4583 O O . TRP B 2 48 ? -141.332 -163.916 235.214 1.00 68.76 ? 48 TRP L O 1 ATOM 4584 C CB . TRP B 2 48 ? -143.065 -166.400 236.627 1.00 62.87 ? 48 TRP L CB 1 ATOM 4585 C CG . TRP B 2 48 ? -141.830 -166.576 237.437 1.00 65.50 ? 48 TRP L CG 1 ATOM 4586 C CD1 . TRP B 2 48 ? -140.680 -167.202 237.058 1.00 67.27 ? 48 TRP L CD1 1 ATOM 4587 C CD2 . TRP B 2 48 ? -141.611 -166.116 238.783 1.00 69.65 ? 48 TRP L CD2 1 ATOM 4588 N NE1 . TRP B 2 48 ? -139.747 -167.161 238.090 1.00 67.09 ? 48 TRP L NE1 1 ATOM 4589 C CE2 . TRP B 2 48 ? -140.298 -166.497 239.151 1.00 61.12 ? 48 TRP L CE2 1 ATOM 4590 C CE3 . TRP B 2 48 ? -142.390 -165.395 239.705 1.00 69.08 ? 48 TRP L CE3 1 ATOM 4591 C CZ2 . TRP B 2 48 ? -139.758 -166.191 240.390 1.00 65.60 ? 48 TRP L CZ2 1 ATOM 4592 C CZ3 . TRP B 2 48 ? -141.836 -165.089 240.949 1.00 62.25 ? 48 TRP L CZ3 1 ATOM 4593 C CH2 . TRP B 2 48 ? -140.539 -165.491 241.274 1.00 61.49 ? 48 TRP L CH2 1 ATOM 4594 N N . ILE B 2 49 ? -142.550 -165.254 233.879 1.00 64.98 ? 49 ILE L N 1 ATOM 4595 C CA . ILE B 2 49 ? -141.794 -164.940 232.681 1.00 67.02 ? 49 ILE L CA 1 ATOM 4596 C C . ILE B 2 49 ? -142.789 -164.882 231.544 1.00 70.23 ? 49 ILE L C 1 ATOM 4597 O O . ILE B 2 49 ? -143.600 -165.801 231.383 1.00 69.28 ? 49 ILE L O 1 ATOM 4598 C CB . ILE B 2 49 ? -140.709 -165.978 232.389 1.00 63.01 ? 49 ILE L CB 1 ATOM 4599 C CG1 . ILE B 2 49 ? -139.743 -166.071 233.567 1.00 65.98 ? 49 ILE L CG1 1 ATOM 4600 C CG2 . ILE B 2 49 ? -139.952 -165.589 231.169 1.00 65.21 ? 49 ILE L CG2 1 ATOM 4601 C CD1 . ILE B 2 49 ? -138.766 -167.212 233.470 1.00 60.70 ? 49 ILE L CD1 1 ATOM 4602 N N . TYR B 2 50 ? -142.757 -163.806 230.762 1.00 65.36 ? 50 TYR L N 1 ATOM 4603 C CA . TYR B 2 50 ? -143.737 -163.677 229.708 1.00 67.23 ? 50 TYR L CA 1 ATOM 4604 C C . TYR B 2 50 ? -143.052 -163.541 228.360 1.00 68.89 ? 50 TYR L C 1 ATOM 4605 O O . TYR B 2 50 ? -141.971 -162.969 228.260 1.00 69.50 ? 50 TYR L O 1 ATOM 4606 C CB . TYR B 2 50 ? -144.680 -162.503 229.990 1.00 73.44 ? 50 TYR L CB 1 ATOM 4607 C CG . TYR B 2 50 ? -144.046 -161.143 229.940 1.00 79.48 ? 50 TYR L CG 1 ATOM 4608 C CD1 . TYR B 2 50 ? -143.960 -160.447 228.736 1.00 77.11 ? 50 TYR L CD1 1 ATOM 4609 C CD2 . TYR B 2 50 ? -143.542 -160.536 231.096 1.00 76.10 ? 50 TYR L CD2 1 ATOM 4610 C CE1 . TYR B 2 50 ? -143.367 -159.195 228.680 1.00 78.98 ? 50 TYR L CE1 1 ATOM 4611 C CE2 . TYR B 2 50 ? -142.952 -159.275 231.039 1.00 77.27 ? 50 TYR L CE2 1 ATOM 4612 C CZ . TYR B 2 50 ? -142.871 -158.617 229.829 1.00 80.30 ? 50 TYR L CZ 1 ATOM 4613 O OH . TYR B 2 50 ? -142.296 -157.371 229.755 1.00 90.74 ? 50 TYR L OH 1 ATOM 4614 N N . SER B 2 51 ? -143.687 -164.105 227.337 1.00 67.40 ? 51 SER L N 1 ATOM 4615 C CA . SER B 2 51 ? -143.097 -164.247 226.007 1.00 73.05 ? 51 SER L CA 1 ATOM 4616 C C . SER B 2 51 ? -141.639 -164.688 226.101 1.00 71.11 ? 51 SER L C 1 ATOM 4617 O O . SER B 2 51 ? -140.734 -163.951 225.740 1.00 71.93 ? 51 SER L O 1 ATOM 4618 C CB . SER B 2 51 ? -143.223 -162.955 225.202 1.00 70.97 ? 51 SER L CB 1 ATOM 4619 O OG . SER B 2 51 ? -142.358 -161.978 225.715 1.00 81.73 ? 51 SER L OG 1 ATOM 4620 N N . THR B 2 52 ? -141.446 -165.891 226.630 1.00 69.10 ? 52 THR L N 1 ATOM 4621 C CA . THR B 2 52 ? -140.168 -166.581 226.611 1.00 70.43 ? 52 THR L CA 1 ATOM 4622 C C . THR B 2 52 ? -139.087 -166.054 227.544 1.00 72.52 ? 52 THR L C 1 ATOM 4623 O O . THR B 2 52 ? -138.650 -166.768 228.445 1.00 69.14 ? 52 THR L O 1 ATOM 4624 C CB . THR B 2 52 ? -139.578 -166.586 225.199 1.00 69.20 ? 52 THR L CB 1 ATOM 4625 O OG1 . THR B 2 52 ? -140.484 -167.253 224.313 1.00 68.05 ? 52 THR L OG1 1 ATOM 4626 C CG2 . THR B 2 52 ? -138.244 -167.314 225.207 1.00 70.51 ? 52 THR L CG2 1 ATOM 4627 N N . SER B 2 53 ? -138.635 -164.825 227.303 1.00 78.82 ? 53 SER L N 1 ATOM 4628 C CA . SER B 2 53 ? -137.455 -164.275 227.982 1.00 71.49 ? 53 SER L CA 1 ATOM 4629 C C . SER B 2 53 ? -137.697 -163.228 229.062 1.00 72.46 ? 53 SER L C 1 ATOM 4630 O O . SER B 2 53 ? -136.795 -162.929 229.841 1.00 68.43 ? 53 SER L O 1 ATOM 4631 C CB . SER B 2 53 ? -136.536 -163.659 226.939 1.00 68.58 ? 53 SER L CB 1 ATOM 4632 O OG . SER B 2 53 ? -135.981 -164.673 226.122 1.00 90.88 ? 53 SER L OG 1 ATOM 4633 N N . ASN B 2 54 ? -138.904 -162.675 229.112 1.00 73.71 ? 54 ASN L N 1 ATOM 4634 C CA . ASN B 2 54 ? -139.142 -161.453 229.876 1.00 71.83 ? 54 ASN L CA 1 ATOM 4635 C C . ASN B 2 54 ? -139.573 -161.652 231.311 1.00 71.49 ? 54 ASN L C 1 ATOM 4636 O O . ASN B 2 54 ? -140.701 -162.064 231.563 1.00 73.00 ? 54 ASN L O 1 ATOM 4637 C CB . ASN B 2 54 ? -140.186 -160.599 229.161 1.00 70.84 ? 54 ASN L CB 1 ATOM 4638 C CG . ASN B 2 54 ? -139.675 -160.063 227.853 1.00 71.47 ? 54 ASN L CG 1 ATOM 4639 O OD1 . ASN B 2 54 ? -138.859 -159.141 227.835 1.00 79.68 ? 54 ASN L OD1 1 ATOM 4640 N ND2 . ASN B 2 54 ? -140.131 -160.646 226.747 1.00 67.58 ? 54 ASN L ND2 1 ATOM 4641 N N . LEU B 2 55 ? -138.683 -161.321 232.243 1.00 69.06 ? 55 LEU L N 1 ATOM 4642 C CA . LEU B 2 55 ? -138.994 -161.430 233.658 1.00 68.27 ? 55 LEU L CA 1 ATOM 4643 C C . LEU B 2 55 ? -140.155 -160.527 234.016 1.00 66.36 ? 55 LEU L C 1 ATOM 4644 O O . LEU B 2 55 ? -140.218 -159.396 233.558 1.00 71.03 ? 55 LEU L O 1 ATOM 4645 C CB . LEU B 2 55 ? -137.771 -161.075 234.506 1.00 69.06 ? 55 LEU L CB 1 ATOM 4646 C CG . LEU B 2 55 ? -136.546 -161.961 234.291 1.00 67.00 ? 55 LEU L CG 1 ATOM 4647 C CD1 . LEU B 2 55 ? -135.551 -161.771 235.413 1.00 69.29 ? 55 LEU L CD1 1 ATOM 4648 C CD2 . LEU B 2 55 ? -136.957 -163.426 234.185 1.00 71.02 ? 55 LEU L CD2 1 ATOM 4649 N N . ALA B 2 56 ? -141.074 -161.037 234.831 1.00 70.26 ? 56 ALA L N 1 ATOM 4650 C CA . ALA B 2 56 ? -142.217 -160.252 235.309 1.00 71.13 ? 56 ALA L CA 1 ATOM 4651 C C . ALA B 2 56 ? -141.774 -159.278 236.379 1.00 79.57 ? 56 ALA L C 1 ATOM 4652 O O . ALA B 2 56 ? -140.629 -159.325 236.839 1.00 86.45 ? 56 ALA L O 1 ATOM 4653 C CB . ALA B 2 56 ? -143.301 -161.148 235.846 1.00 75.62 ? 56 ALA L CB 1 ATOM 4654 N N . SER B 2 57 ? -142.664 -158.374 236.766 1.00 83.81 ? 57 SER L N 1 ATOM 4655 C CA . SER B 2 57 ? -142.296 -157.420 237.795 1.00 88.58 ? 57 SER L CA 1 ATOM 4656 C C . SER B 2 57 ? -141.996 -158.135 239.112 1.00 83.29 ? 57 SER L C 1 ATOM 4657 O O . SER B 2 57 ? -142.761 -158.994 239.560 1.00 81.50 ? 57 SER L O 1 ATOM 4658 C CB . SER B 2 57 ? -143.413 -156.388 237.985 1.00 90.63 ? 57 SER L CB 1 ATOM 4659 O OG . SER B 2 57 ? -142.876 -155.173 238.491 1.00 94.67 ? 57 SER L OG 1 ATOM 4660 N N . GLY B 2 58 ? -140.884 -157.755 239.736 1.00 77.35 ? 58 GLY L N 1 ATOM 4661 C CA . GLY B 2 58 ? -140.522 -158.302 241.028 1.00 79.78 ? 58 GLY L CA 1 ATOM 4662 C C . GLY B 2 58 ? -139.778 -159.625 240.970 1.00 78.09 ? 58 GLY L C 1 ATOM 4663 O O . GLY B 2 58 ? -139.408 -160.166 242.007 1.00 77.00 ? 58 GLY L O 1 ATOM 4664 N N . VAL B 2 59 ? -139.551 -160.145 239.769 1.00 75.59 ? 59 VAL L N 1 ATOM 4665 C CA . VAL B 2 59 ? -138.879 -161.429 239.608 1.00 70.36 ? 59 VAL L CA 1 ATOM 4666 C C . VAL B 2 59 ? -137.359 -161.228 239.600 1.00 72.58 ? 59 VAL L C 1 ATOM 4667 O O . VAL B 2 59 ? -136.826 -160.521 238.748 1.00 72.76 ? 59 VAL L O 1 ATOM 4668 C CB . VAL B 2 59 ? -139.325 -162.137 238.304 1.00 73.08 ? 59 VAL L CB 1 ATOM 4669 C CG1 . VAL B 2 59 ? -138.488 -163.381 238.049 1.00 72.19 ? 59 VAL L CG1 1 ATOM 4670 C CG2 . VAL B 2 59 ? -140.831 -162.466 238.333 1.00 65.36 ? 59 VAL L CG2 1 ATOM 4671 N N . PRO B 2 60 ? -136.649 -161.869 240.539 1.00 70.85 ? 60 PRO L N 1 ATOM 4672 C CA . PRO B 2 60 ? -135.208 -161.651 240.659 1.00 69.45 ? 60 PRO L CA 1 ATOM 4673 C C . PRO B 2 60 ? -134.462 -162.123 239.427 1.00 70.72 ? 60 PRO L C 1 ATOM 4674 O O . PRO B 2 60 ? -134.907 -163.029 238.725 1.00 72.20 ? 60 PRO L O 1 ATOM 4675 C CB . PRO B 2 60 ? -134.813 -162.475 241.891 1.00 63.96 ? 60 PRO L CB 1 ATOM 4676 C CG . PRO B 2 60 ? -135.892 -163.438 242.098 1.00 73.43 ? 60 PRO L CG 1 ATOM 4677 C CD . PRO B 2 60 ? -137.151 -162.791 241.574 1.00 79.25 ? 60 PRO L CD 1 ATOM 4678 N N . ALA B 2 61 ? -133.329 -161.484 239.169 1.00 74.34 ? 61 ALA L N 1 ATOM 4679 C CA . ALA B 2 61 ? -132.561 -161.705 237.953 1.00 73.92 ? 61 ALA L CA 1 ATOM 4680 C C . ALA B 2 61 ? -132.038 -163.141 237.805 1.00 74.33 ? 61 ALA L C 1 ATOM 4681 O O . ALA B 2 61 ? -131.560 -163.499 236.725 1.00 71.49 ? 61 ALA L O 1 ATOM 4682 C CB . ALA B 2 61 ? -131.417 -160.743 237.897 1.00 71.27 ? 61 ALA L CB 1 ATOM 4683 N N . ARG B 2 62 ? -132.119 -163.954 238.867 1.00 72.32 ? 62 ARG L N 1 ATOM 4684 C CA . ARG B 2 62 ? -131.670 -165.346 238.777 1.00 68.50 ? 62 ARG L CA 1 ATOM 4685 C C . ARG B 2 62 ? -132.374 -166.048 237.634 1.00 75.62 ? 62 ARG L C 1 ATOM 4686 O O . ARG B 2 62 ? -131.824 -166.950 236.999 1.00 78.10 ? 62 ARG L O 1 ATOM 4687 C CB . ARG B 2 62 ? -131.989 -166.141 240.036 1.00 71.29 ? 62 ARG L CB 1 ATOM 4688 C CG . ARG B 2 62 ? -131.900 -165.464 241.359 1.00 75.82 ? 62 ARG L CG 1 ATOM 4689 C CD . ARG B 2 62 ? -131.995 -166.540 242.435 1.00 75.71 ? 62 ARG L CD 1 ATOM 4690 N NE . ARG B 2 62 ? -133.323 -166.648 243.019 1.00 70.36 ? 62 ARG L NE 1 ATOM 4691 C CZ . ARG B 2 62 ? -133.835 -165.730 243.832 1.00 74.51 ? 62 ARG L CZ 1 ATOM 4692 N NH1 . ARG B 2 62 ? -133.143 -164.640 244.122 1.00 77.00 ? 62 ARG L NH1 1 ATOM 4693 N NH2 . ARG B 2 62 ? -135.043 -165.879 244.340 1.00 75.65 ? 62 ARG L NH2 1 ATOM 4694 N N . PHE B 2 63 ? -133.626 -165.659 237.423 1.00 74.23 ? 63 PHE L N 1 ATOM 4695 C CA . PHE B 2 63 ? -134.469 -166.330 236.460 1.00 69.99 ? 63 PHE L CA 1 ATOM 4696 C C . PHE B 2 63 ? -134.181 -165.853 235.049 1.00 71.98 ? 63 PHE L C 1 ATOM 4697 O O . PHE B 2 63 ? -133.785 -164.712 234.820 1.00 78.86 ? 63 PHE L O 1 ATOM 4698 C CB . PHE B 2 63 ? -135.935 -166.126 236.814 1.00 73.47 ? 63 PHE L CB 1 ATOM 4699 C CG . PHE B 2 63 ? -136.330 -166.782 238.107 1.00 68.97 ? 63 PHE L CG 1 ATOM 4700 C CD1 . PHE B 2 63 ? -136.841 -168.069 238.121 1.00 65.09 ? 63 PHE L CD1 1 ATOM 4701 C CD2 . PHE B 2 63 ? -136.151 -166.121 239.311 1.00 67.67 ? 63 PHE L CD2 1 ATOM 4702 C CE1 . PHE B 2 63 ? -137.189 -168.684 239.313 1.00 66.46 ? 63 PHE L CE1 1 ATOM 4703 C CE2 . PHE B 2 63 ? -136.496 -166.724 240.509 1.00 71.07 ? 63 PHE L CE2 1 ATOM 4704 C CZ . PHE B 2 63 ? -137.015 -168.013 240.511 1.00 68.00 ? 63 PHE L CZ 1 ATOM 4705 N N . SER B 2 64 ? -134.393 -166.753 234.103 1.00 75.76 ? 64 SER L N 1 ATOM 4706 C CA . SER B 2 64 ? -134.203 -166.483 232.695 1.00 70.55 ? 64 SER L CA 1 ATOM 4707 C C . SER B 2 64 ? -134.981 -167.547 231.939 1.00 68.31 ? 64 SER L C 1 ATOM 4708 O O . SER B 2 64 ? -135.213 -168.645 232.453 1.00 64.82 ? 64 SER L O 1 ATOM 4709 C CB . SER B 2 64 ? -132.727 -166.518 232.325 1.00 68.49 ? 64 SER L CB 1 ATOM 4710 O OG . SER B 2 64 ? -132.310 -167.842 232.038 1.00 72.61 ? 64 SER L OG 1 ATOM 4711 N N . GLY B 2 65 ? -135.386 -167.226 230.723 1.00 67.88 ? 65 GLY L N 1 ATOM 4712 C CA . GLY B 2 65 ? -136.189 -168.139 229.945 1.00 62.64 ? 65 GLY L CA 1 ATOM 4713 C C . GLY B 2 65 ? -135.741 -168.113 228.509 1.00 67.62 ? 65 GLY L C 1 ATOM 4714 O O . GLY B 2 65 ? -135.308 -167.082 228.000 1.00 69.42 ? 65 GLY L O 1 ATOM 4715 N N . SER B 2 66 ? -135.866 -169.251 227.842 1.00 69.97 ? 66 SER L N 1 ATOM 4716 C CA . SER B 2 66 ? -135.343 -169.395 226.502 1.00 69.07 ? 66 SER L CA 1 ATOM 4717 C C . SER B 2 66 ? -136.158 -170.416 225.717 1.00 71.01 ? 66 SER L C 1 ATOM 4718 O O . SER B 2 66 ? -136.833 -171.262 226.308 1.00 73.93 ? 66 SER L O 1 ATOM 4719 C CB . SER B 2 66 ? -133.879 -169.810 226.570 1.00 67.81 ? 66 SER L CB 1 ATOM 4720 O OG . SER B 2 66 ? -133.593 -170.771 225.571 1.00 92.20 ? 66 SER L OG 1 ATOM 4721 N N . GLY B 2 67 ? -136.112 -170.332 224.389 1.00 66.36 ? 67 GLY L N 1 ATOM 4722 C CA . GLY B 2 67 ? -136.784 -171.310 223.553 1.00 68.26 ? 67 GLY L CA 1 ATOM 4723 C C . GLY B 2 67 ? -137.494 -170.772 222.323 1.00 69.28 ? 67 GLY L C 1 ATOM 4724 O O . GLY B 2 67 ? -137.460 -169.575 222.032 1.00 72.31 ? 67 GLY L O 1 ATOM 4725 N N . SER B 2 68 ? -138.120 -171.678 221.582 1.00 67.47 ? 68 SER L N 1 ATOM 4726 C CA . SER B 2 68 ? -138.853 -171.314 220.375 1.00 74.11 ? 68 SER L CA 1 ATOM 4727 C C . SER B 2 68 ? -139.612 -172.521 219.821 1.00 75.29 ? 68 SER L C 1 ATOM 4728 O O . SER B 2 68 ? -139.336 -173.666 220.189 1.00 73.62 ? 68 SER L O 1 ATOM 4729 C CB . SER B 2 68 ? -137.900 -170.771 219.316 1.00 72.87 ? 68 SER L CB 1 ATOM 4730 O OG . SER B 2 68 ? -136.822 -171.683 219.137 1.00 81.74 ? 68 SER L OG 1 ATOM 4731 N N . GLY B 2 69 ? -140.567 -172.269 218.935 1.00 74.13 ? 69 GLY L N 1 ATOM 4732 C CA . GLY B 2 69 ? -141.279 -173.352 218.288 1.00 74.27 ? 69 GLY L CA 1 ATOM 4733 C C . GLY B 2 69 ? -141.963 -174.237 219.294 1.00 74.40 ? 69 GLY L C 1 ATOM 4734 O O . GLY B 2 69 ? -142.954 -173.834 219.900 1.00 76.59 ? 69 GLY L O 1 ATOM 4735 N N . THR B 2 70 ? -141.439 -175.449 219.462 1.00 75.03 ? 70 THR L N 1 ATOM 4736 C CA . THR B 2 70 ? -142.067 -176.424 220.341 1.00 71.42 ? 70 THR L CA 1 ATOM 4737 C C . THR B 2 70 ? -141.224 -176.747 221.556 1.00 73.44 ? 70 THR L C 1 ATOM 4738 O O . THR B 2 70 ? -141.520 -177.702 222.281 1.00 75.54 ? 70 THR L O 1 ATOM 4739 C CB . THR B 2 70 ? -142.363 -177.752 219.623 1.00 73.95 ? 70 THR L CB 1 ATOM 4740 O OG1 . THR B 2 70 ? -141.134 -178.419 219.321 1.00 73.31 ? 70 THR L OG1 1 ATOM 4741 C CG2 . THR B 2 70 ? -143.156 -177.523 218.368 1.00 72.91 ? 70 THR L CG2 1 ATOM 4742 N N . SER B 2 71 ? -140.172 -175.971 221.780 1.00 69.65 ? 71 SER L N 1 ATOM 4743 C CA . SER B 2 71 ? -139.291 -176.257 222.899 1.00 68.75 ? 71 SER L CA 1 ATOM 4744 C C . SER B 2 71 ? -138.835 -174.995 223.626 1.00 75.09 ? 71 SER L C 1 ATOM 4745 O O . SER B 2 71 ? -138.249 -174.088 223.022 1.00 76.95 ? 71 SER L O 1 ATOM 4746 C CB . SER B 2 71 ? -138.078 -177.042 222.420 1.00 75.12 ? 71 SER L CB 1 ATOM 4747 O OG . SER B 2 71 ? -137.131 -177.171 223.470 1.00 89.17 ? 71 SER L OG 1 ATOM 4748 N N . TYR B 2 72 ? -139.097 -174.947 224.930 1.00 70.18 ? 72 TYR L N 1 ATOM 4749 C CA . TYR B 2 72 ? -138.769 -173.790 225.756 1.00 69.14 ? 72 TYR L CA 1 ATOM 4750 C C . TYR B 2 72 ? -138.206 -174.266 227.089 1.00 74.18 ? 72 TYR L C 1 ATOM 4751 O O . TYR B 2 72 ? -138.333 -175.450 227.438 1.00 75.90 ? 72 TYR L O 1 ATOM 4752 C CB . TYR B 2 72 ? -139.998 -172.925 225.992 1.00 64.67 ? 72 TYR L CB 1 ATOM 4753 C CG . TYR B 2 72 ? -140.535 -172.265 224.746 1.00 67.55 ? 72 TYR L CG 1 ATOM 4754 C CD1 . TYR B 2 72 ? -140.338 -170.904 224.514 1.00 71.25 ? 72 TYR L CD1 1 ATOM 4755 C CD2 . TYR B 2 72 ? -141.242 -172.990 223.800 1.00 67.26 ? 72 TYR L CD2 1 ATOM 4756 C CE1 . TYR B 2 72 ? -140.822 -170.292 223.376 1.00 69.41 ? 72 TYR L CE1 1 ATOM 4757 C CE2 . TYR B 2 72 ? -141.726 -172.383 222.657 1.00 71.12 ? 72 TYR L CE2 1 ATOM 4758 C CZ . TYR B 2 72 ? -141.514 -171.034 222.451 1.00 71.14 ? 72 TYR L CZ 1 ATOM 4759 O OH . TYR B 2 72 ? -141.999 -170.433 221.309 1.00 73.06 ? 72 TYR L OH 1 ATOM 4760 N N . SER B 2 73 ? -137.580 -173.364 227.840 1.00 67.95 ? 73 SER L N 1 ATOM 4761 C CA . SER B 2 73 ? -136.997 -173.747 229.118 1.00 69.49 ? 73 SER L CA 1 ATOM 4762 C C . SER B 2 73 ? -136.888 -172.595 230.129 1.00 72.92 ? 73 SER L C 1 ATOM 4763 O O . SER B 2 73 ? -136.681 -171.436 229.763 1.00 69.08 ? 73 SER L O 1 ATOM 4764 C CB . SER B 2 73 ? -135.614 -174.331 228.882 1.00 66.19 ? 73 SER L CB 1 ATOM 4765 O OG . SER B 2 73 ? -134.773 -173.347 228.307 1.00 79.14 ? 73 SER L OG 1 ATOM 4766 N N . LEU B 2 74 ? -137.027 -172.926 231.406 1.00 71.84 ? 74 LEU L N 1 ATOM 4767 C CA . LEU B 2 74 ? -136.791 -171.971 232.479 1.00 67.73 ? 74 LEU L CA 1 ATOM 4768 C C . LEU B 2 74 ? -135.469 -172.329 233.108 1.00 69.08 ? 74 LEU L C 1 ATOM 4769 O O . LEU B 2 74 ? -135.155 -173.512 233.269 1.00 68.76 ? 74 LEU L O 1 ATOM 4770 C CB . LEU B 2 74 ? -137.922 -172.009 233.514 1.00 71.69 ? 74 LEU L CB 1 ATOM 4771 C CG . LEU B 2 74 ? -137.955 -170.931 234.593 1.00 66.81 ? 74 LEU L CG 1 ATOM 4772 C CD1 . LEU B 2 74 ? -139.363 -170.399 234.708 1.00 62.87 ? 74 LEU L CD1 1 ATOM 4773 C CD2 . LEU B 2 74 ? -137.490 -171.505 235.921 1.00 66.41 ? 74 LEU L CD2 1 ATOM 4774 N N . THR B 2 75 ? -134.684 -171.320 233.458 1.00 69.41 ? 75 THR L N 1 ATOM 4775 C CA . THR B 2 75 ? -133.417 -171.573 234.121 1.00 71.18 ? 75 THR L CA 1 ATOM 4776 C C . THR B 2 75 ? -133.286 -170.660 235.318 1.00 75.81 ? 75 THR L C 1 ATOM 4777 O O . THR B 2 75 ? -133.571 -169.462 235.231 1.00 76.09 ? 75 THR L O 1 ATOM 4778 C CB . THR B 2 75 ? -132.194 -171.350 233.200 1.00 68.73 ? 75 THR L CB 1 ATOM 4779 O OG1 . THR B 2 75 ? -132.149 -172.357 232.185 1.00 73.54 ? 75 THR L OG1 1 ATOM 4780 C CG2 . THR B 2 75 ? -130.921 -171.436 234.009 1.00 69.40 ? 75 THR L CG2 1 ATOM 4781 N N . ILE B 2 76 ? -132.865 -171.239 236.437 1.00 70.36 ? 76 ILE L N 1 ATOM 4782 C CA . ILE B 2 76 ? -132.473 -170.469 237.598 1.00 70.10 ? 76 ILE L CA 1 ATOM 4783 C C . ILE B 2 76 ? -130.963 -170.616 237.730 1.00 74.94 ? 76 ILE L C 1 ATOM 4784 O O . ILE B 2 76 ? -130.465 -171.716 237.948 1.00 79.07 ? 76 ILE L O 1 ATOM 4785 C CB . ILE B 2 76 ? -133.194 -170.953 238.868 1.00 73.47 ? 76 ILE L CB 1 ATOM 4786 C CG1 . ILE B 2 76 ? -134.698 -171.092 238.612 1.00 70.58 ? 76 ILE L CG1 1 ATOM 4787 C CG2 . ILE B 2 76 ? -132.926 -170.015 240.019 1.00 72.87 ? 76 ILE L CG2 1 ATOM 4788 C CD1 . ILE B 2 76 ? -135.453 -171.802 239.725 1.00 64.38 ? 76 ILE L CD1 1 ATOM 4789 N N . SER B 2 77 ? -130.235 -169.517 237.553 1.00 80.96 ? 77 SER L N 1 ATOM 4790 C CA . SER B 2 77 ? -128.771 -169.539 237.571 1.00 78.56 ? 77 SER L CA 1 ATOM 4791 C C . SER B 2 77 ? -128.156 -169.900 238.933 1.00 83.90 ? 77 SER L C 1 ATOM 4792 O O . SER B 2 77 ? -127.131 -170.601 238.986 1.00 90.20 ? 77 SER L O 1 ATOM 4793 C CB . SER B 2 77 ? -128.240 -168.188 237.150 1.00 68.96 ? 77 SER L CB 1 ATOM 4794 O OG . SER B 2 77 ? -128.503 -167.258 238.182 1.00 80.39 ? 77 SER L OG 1 ATOM 4795 N N . SER B 2 78 ? -128.770 -169.440 240.026 1.00 72.51 ? 78 SER L N 1 ATOM 4796 C CA . SER B 2 78 ? -128.359 -169.879 241.368 1.00 75.16 ? 78 SER L CA 1 ATOM 4797 C C . SER B 2 78 ? -129.542 -169.968 242.332 1.00 76.96 ? 78 SER L C 1 ATOM 4798 O O . SER B 2 78 ? -130.011 -168.951 242.858 1.00 79.03 ? 78 SER L O 1 ATOM 4799 C CB . SER B 2 78 ? -127.300 -168.949 241.939 1.00 75.61 ? 78 SER L CB 1 ATOM 4800 O OG . SER B 2 78 ? -126.014 -169.518 241.792 1.00 78.54 ? 78 SER L OG 1 ATOM 4801 N N . VAL B 2 79 ? -129.995 -171.192 242.583 1.00 73.50 ? 79 VAL L N 1 ATOM 4802 C CA . VAL B 2 79 ? -131.256 -171.418 243.277 1.00 74.32 ? 79 VAL L CA 1 ATOM 4803 C C . VAL B 2 79 ? -131.255 -170.912 244.709 1.00 75.19 ? 79 VAL L C 1 ATOM 4804 O O . VAL B 2 79 ? -130.230 -170.943 245.397 1.00 71.81 ? 79 VAL L O 1 ATOM 4805 C CB . VAL B 2 79 ? -131.620 -172.908 243.304 1.00 71.61 ? 79 VAL L CB 1 ATOM 4806 C CG1 . VAL B 2 79 ? -133.047 -173.076 243.800 1.00 75.92 ? 79 VAL L CG1 1 ATOM 4807 C CG2 . VAL B 2 79 ? -131.525 -173.469 241.939 1.00 81.14 ? 79 VAL L CG2 1 ATOM 4808 N N . GLU B 2 80 ? -132.418 -170.453 245.158 1.00 76.09 ? 80 GLU L N 1 ATOM 4809 C CA . GLU B 2 80 ? -132.587 -170.083 246.555 1.00 74.74 ? 80 GLU L CA 1 ATOM 4810 C C . GLU B 2 80 ? -133.799 -170.784 247.142 1.00 73.37 ? 80 GLU L C 1 ATOM 4811 O O . GLU B 2 80 ? -134.724 -171.146 246.423 1.00 80.95 ? 80 GLU L O 1 ATOM 4812 C CB . GLU B 2 80 ? -132.699 -168.572 246.689 1.00 76.76 ? 80 GLU L CB 1 ATOM 4813 C CG . GLU B 2 80 ? -131.530 -167.891 246.011 1.00 77.84 ? 80 GLU L CG 1 ATOM 4814 C CD . GLU B 2 80 ? -131.411 -166.424 246.332 1.00 88.11 ? 80 GLU L CD 1 ATOM 4815 O OE1 . GLU B 2 80 ? -132.198 -165.915 247.171 1.00 93.42 ? 80 GLU L OE1 1 ATOM 4816 O OE2 . GLU B 2 80 ? -130.524 -165.776 245.730 1.00 93.39 ? 80 GLU L OE2 1 ATOM 4817 N N . ALA B 2 81 ? -133.785 -170.998 248.448 1.00 78.77 ? 81 ALA L N 1 ATOM 4818 C CA . ALA B 2 81 ? -134.827 -171.787 249.087 1.00 74.87 ? 81 ALA L CA 1 ATOM 4819 C C . ALA B 2 81 ? -136.187 -171.140 248.893 1.00 73.19 ? 81 ALA L C 1 ATOM 4820 O O . ALA B 2 81 ? -137.207 -171.827 248.903 1.00 79.80 ? 81 ALA L O 1 ATOM 4821 C CB . ALA B 2 81 ? -134.531 -171.956 250.559 1.00 75.46 ? 81 ALA L CB 1 ATOM 4822 N N . GLU B 2 82 ? -136.207 -169.824 248.717 1.00 73.17 ? 82 GLU L N 1 ATOM 4823 C CA . GLU B 2 82 ? -137.461 -169.135 248.456 1.00 76.85 ? 82 GLU L CA 1 ATOM 4824 C C . GLU B 2 82 ? -137.985 -169.471 247.063 1.00 77.40 ? 82 GLU L C 1 ATOM 4825 O O . GLU B 2 82 ? -139.142 -169.211 246.762 1.00 82.80 ? 82 GLU L O 1 ATOM 4826 C CB . GLU B 2 82 ? -137.303 -167.623 248.608 1.00 77.94 ? 82 GLU L CB 1 ATOM 4827 C CG . GLU B 2 82 ? -136.480 -166.948 247.511 1.00 85.43 ? 82 GLU L CG 1 ATOM 4828 C CD . GLU B 2 82 ? -136.574 -165.417 247.566 1.00 94.77 ? 82 GLU L CD 1 ATOM 4829 O OE1 . GLU B 2 82 ? -137.425 -164.907 248.333 1.00 95.85 ? 82 GLU L OE1 1 ATOM 4830 O OE2 . GLU B 2 82 ? -135.809 -164.727 246.844 1.00 90.85 ? 82 GLU L OE2 1 ATOM 4831 N N . ASP B 2 83 ? -137.130 -170.042 246.219 1.00 76.23 ? 83 ASP L N 1 ATOM 4832 C CA . ASP B 2 83 ? -137.500 -170.421 244.855 1.00 70.27 ? 83 ASP L CA 1 ATOM 4833 C C . ASP B 2 83 ? -138.241 -171.737 244.723 1.00 69.53 ? 83 ASP L C 1 ATOM 4834 O O . ASP B 2 83 ? -138.736 -172.046 243.636 1.00 67.57 ? 83 ASP L O 1 ATOM 4835 C CB . ASP B 2 83 ? -136.261 -170.492 243.978 1.00 67.09 ? 83 ASP L CB 1 ATOM 4836 C CG . ASP B 2 83 ? -135.671 -169.147 243.742 1.00 74.36 ? 83 ASP L CG 1 ATOM 4837 O OD1 . ASP B 2 83 ? -136.377 -168.161 244.058 1.00 83.92 ? 83 ASP L OD1 1 ATOM 4838 O OD2 . ASP B 2 83 ? -134.527 -169.056 243.253 1.00 76.25 ? 83 ASP L OD2 1 ATOM 4839 N N . ALA B 2 84 ? -138.295 -172.522 245.798 1.00 70.36 ? 84 ALA L N 1 ATOM 4840 C CA . ALA B 2 84 ? -139.023 -173.787 245.771 1.00 66.90 ? 84 ALA L CA 1 ATOM 4841 C C . ALA B 2 84 ? -140.503 -173.553 245.529 1.00 70.13 ? 84 ALA L C 1 ATOM 4842 O O . ALA B 2 84 ? -141.179 -172.899 246.335 1.00 72.03 ? 84 ALA L O 1 ATOM 4843 C CB . ALA B 2 84 ? -138.820 -174.541 247.069 1.00 67.03 ? 84 ALA L CB 1 ATOM 4844 N N . ALA B 2 85 ? -141.011 -174.123 244.440 1.00 69.08 ? 85 ALA L N 1 ATOM 4845 C CA . ALA B 2 85 ? -142.423 -173.975 244.060 1.00 67.16 ? 85 ALA L CA 1 ATOM 4846 C C . ALA B 2 85 ? -142.729 -174.871 242.868 1.00 70.96 ? 85 ALA L C 1 ATOM 4847 O O . ALA B 2 85 ? -141.856 -175.604 242.399 1.00 73.55 ? 85 ALA L O 1 ATOM 4848 C CB . ALA B 2 85 ? -142.752 -172.538 243.730 1.00 64.67 ? 85 ALA L CB 1 ATOM 4849 N N . THR B 2 86 ? -143.961 -174.836 242.374 1.00 68.11 ? 86 THR L N 1 ATOM 4850 C CA . THR B 2 86 ? -144.227 -175.503 241.115 1.00 67.57 ? 86 THR L CA 1 ATOM 4851 C C . THR B 2 86 ? -144.249 -174.468 240.001 1.00 65.04 ? 86 THR L C 1 ATOM 4852 O O . THR B 2 86 ? -144.895 -173.430 240.116 1.00 65.55 ? 86 THR L O 1 ATOM 4853 C CB . THR B 2 86 ? -145.545 -176.296 241.134 1.00 65.39 ? 86 THR L CB 1 ATOM 4854 O OG1 . THR B 2 86 ? -145.461 -177.337 242.112 1.00 71.62 ? 86 THR L OG1 1 ATOM 4855 C CG2 . THR B 2 86 ? -145.768 -176.961 239.792 1.00 62.68 ? 86 THR L CG2 1 ATOM 4856 N N . TYR B 2 87 ? -143.532 -174.753 238.924 1.00 63.86 ? 87 TYR L N 1 ATOM 4857 C CA . TYR B 2 87 ? -143.516 -173.853 237.788 1.00 65.42 ? 87 TYR L CA 1 ATOM 4858 C C . TYR B 2 87 ? -144.402 -174.361 236.665 1.00 65.20 ? 87 TYR L C 1 ATOM 4859 O O . TYR B 2 87 ? -144.274 -175.515 236.244 1.00 68.69 ? 87 TYR L O 1 ATOM 4860 C CB . TYR B 2 87 ? -142.073 -173.658 237.324 1.00 65.43 ? 87 TYR L CB 1 ATOM 4861 C CG . TYR B 2 87 ? -141.288 -172.889 238.360 1.00 61.24 ? 87 TYR L CG 1 ATOM 4862 C CD1 . TYR B 2 87 ? -141.166 -171.507 238.284 1.00 59.32 ? 87 TYR L CD1 1 ATOM 4863 C CD2 . TYR B 2 87 ? -140.732 -173.536 239.448 1.00 61.59 ? 87 TYR L CD2 1 ATOM 4864 C CE1 . TYR B 2 87 ? -140.479 -170.793 239.252 1.00 62.18 ? 87 TYR L CE1 1 ATOM 4865 C CE2 . TYR B 2 87 ? -140.042 -172.841 240.414 1.00 64.64 ? 87 TYR L CE2 1 ATOM 4866 C CZ . TYR B 2 87 ? -139.920 -171.473 240.313 1.00 65.77 ? 87 TYR L CZ 1 ATOM 4867 O OH . TYR B 2 87 ? -139.227 -170.812 241.287 1.00 69.66 ? 87 TYR L OH 1 ATOM 4868 N N . TYR B 2 88 ? -145.291 -173.499 236.175 1.00 59.39 ? 88 TYR L N 1 ATOM 4869 C CA . TYR B 2 88 ? -146.134 -173.858 235.030 1.00 67.22 ? 88 TYR L CA 1 ATOM 4870 C C . TYR B 2 88 ? -145.825 -172.996 233.808 1.00 66.73 ? 88 TYR L C 1 ATOM 4871 O O . TYR B 2 88 ? -145.755 -171.774 233.913 1.00 71.35 ? 88 TYR L O 1 ATOM 4872 C CB . TYR B 2 88 ? -147.623 -173.732 235.379 1.00 65.35 ? 88 TYR L CB 1 ATOM 4873 C CG . TYR B 2 88 ? -148.068 -174.601 236.546 1.00 65.84 ? 88 TYR L CG 1 ATOM 4874 C CD1 . TYR B 2 88 ? -148.568 -175.882 236.343 1.00 63.78 ? 88 TYR L CD1 1 ATOM 4875 C CD2 . TYR B 2 88 ? -147.968 -174.145 237.854 1.00 66.25 ? 88 TYR L CD2 1 ATOM 4876 C CE1 . TYR B 2 88 ? -148.972 -176.674 237.403 1.00 60.02 ? 88 TYR L CE1 1 ATOM 4877 C CE2 . TYR B 2 88 ? -148.374 -174.929 238.918 1.00 67.09 ? 88 TYR L CE2 1 ATOM 4878 C CZ . TYR B 2 88 ? -148.876 -176.196 238.685 1.00 66.72 ? 88 TYR L CZ 1 ATOM 4879 O OH . TYR B 2 88 ? -149.276 -176.988 239.738 1.00 72.26 ? 88 TYR L OH 1 ATOM 4880 N N . CYS B 2 89 ? -145.648 -173.621 232.647 1.00 65.79 ? 89 CYS L N 1 ATOM 4881 C CA . CYS B 2 89 ? -145.561 -172.863 231.401 1.00 67.98 ? 89 CYS L CA 1 ATOM 4882 C C . CYS B 2 89 ? -146.953 -172.720 230.769 1.00 69.37 ? 89 CYS L C 1 ATOM 4883 O O . CYS B 2 89 ? -147.886 -173.434 231.134 1.00 69.90 ? 89 CYS L O 1 ATOM 4884 C CB . CYS B 2 89 ? -144.593 -173.518 230.421 1.00 64.30 ? 89 CYS L CB 1 ATOM 4885 S SG . CYS B 2 89 ? -145.036 -175.153 229.848 1.00 78.02 ? 89 CYS L SG 1 ATOM 4886 N N . GLN B 2 90 ? -147.109 -171.784 229.840 1.00 69.62 ? 90 GLN L N 1 ATOM 4887 C CA . GLN B 2 90 ? -148.402 -171.592 229.192 1.00 69.87 ? 90 GLN L CA 1 ATOM 4888 C C . GLN B 2 90 ? -148.240 -170.985 227.813 1.00 70.56 ? 90 GLN L C 1 ATOM 4889 O O . GLN B 2 90 ? -147.282 -170.247 227.559 1.00 76.01 ? 90 GLN L O 1 ATOM 4890 C CB . GLN B 2 90 ? -149.307 -170.695 230.045 1.00 69.37 ? 90 GLN L CB 1 ATOM 4891 C CG . GLN B 2 90 ? -150.692 -170.458 229.439 1.00 71.95 ? 90 GLN L CG 1 ATOM 4892 C CD . GLN B 2 90 ? -151.085 -168.996 229.436 1.00 71.47 ? 90 GLN L CD 1 ATOM 4893 O OE1 . GLN B 2 90 ? -150.312 -168.140 229.839 1.00 68.49 ? 90 GLN L OE1 1 ATOM 4894 N NE2 . GLN B 2 90 ? -152.297 -168.707 228.986 1.00 69.92 ? 90 GLN L NE2 1 ATOM 4895 N N . GLN B 2 91 ? -149.171 -171.319 226.923 1.00 71.44 ? 91 GLN L N 1 ATOM 4896 C CA . GLN B 2 91 ? -149.308 -170.645 225.628 1.00 75.10 ? 91 GLN L CA 1 ATOM 4897 C C . GLN B 2 91 ? -150.523 -169.710 225.527 1.00 72.55 ? 91 GLN L C 1 ATOM 4898 O O . GLN B 2 91 ? -151.529 -169.953 226.186 1.00 72.74 ? 91 GLN L O 1 ATOM 4899 C CB . GLN B 2 91 ? -149.424 -171.674 224.521 1.00 69.73 ? 91 GLN L CB 1 ATOM 4900 C CG . GLN B 2 91 ? -150.671 -171.445 223.694 1.00 75.03 ? 91 GLN L CG 1 ATOM 4901 C CD . GLN B 2 91 ? -151.430 -172.704 223.574 1.00 78.48 ? 91 GLN L CD 1 ATOM 4902 O OE1 . GLN B 2 91 ? -150.835 -173.777 223.588 1.00 90.41 ? 91 GLN L OE1 1 ATOM 4903 N NE2 . GLN B 2 91 ? -152.744 -172.613 223.509 1.00 76.51 ? 91 GLN L NE2 1 ATOM 4904 N N . PHE B 2 92 ? -150.432 -168.651 224.715 1.00 72.46 ? 92 PHE L N 1 ATOM 4905 C CA . PHE B 2 92 ? -151.633 -168.003 224.155 1.00 73.16 ? 92 PHE L CA 1 ATOM 4906 C C . PHE B 2 92 ? -151.636 -167.990 222.637 1.00 78.13 ? 92 PHE L C 1 ATOM 4907 O O . PHE B 2 92 ? -152.307 -167.144 222.061 1.00 81.42 ? 92 PHE L O 1 ATOM 4908 C CB . PHE B 2 92 ? -151.795 -166.530 224.507 1.00 72.40 ? 92 PHE L CB 1 ATOM 4909 C CG . PHE B 2 92 ? -152.083 -166.219 225.919 1.00 75.61 ? 92 PHE L CG 1 ATOM 4910 C CD1 . PHE B 2 92 ? -153.346 -166.392 226.477 1.00 84.67 ? 92 PHE L CD1 1 ATOM 4911 C CD2 . PHE B 2 92 ? -151.111 -165.576 226.645 1.00 79.56 ? 92 PHE L CD2 1 ATOM 4912 C CE1 . PHE B 2 92 ? -153.583 -166.014 227.786 1.00 87.25 ? 92 PHE L CE1 1 ATOM 4913 C CE2 . PHE B 2 92 ? -151.332 -165.190 227.929 1.00 85.52 ? 92 PHE L CE2 1 ATOM 4914 C CZ . PHE B 2 92 ? -152.565 -165.409 228.514 1.00 87.54 ? 92 PHE L CZ 1 ATOM 4915 N N . SER B 2 93 ? -150.866 -168.834 221.965 1.00 80.42 ? 93 SER L N 1 ATOM 4916 C CA . SER B 2 93 ? -150.829 -168.730 220.515 1.00 75.74 ? 93 SER L CA 1 ATOM 4917 C C . SER B 2 93 ? -152.161 -169.215 219.938 1.00 81.20 ? 93 SER L C 1 ATOM 4918 O O . SER B 2 93 ? -152.469 -168.953 218.777 1.00 93.13 ? 93 SER L O 1 ATOM 4919 C CB . SER B 2 93 ? -149.654 -169.513 219.928 1.00 79.60 ? 93 SER L CB 1 ATOM 4920 O OG . SER B 2 93 ? -149.949 -170.899 219.800 1.00 90.49 ? 93 SER L OG 1 ATOM 4921 N N . GLY B 2 94 ? -152.948 -169.925 220.742 1.00 76.31 ? 94 GLY L N 1 ATOM 4922 C CA . GLY B 2 94 ? -154.203 -170.471 220.255 1.00 75.49 ? 94 GLY L CA 1 ATOM 4923 C C . GLY B 2 94 ? -155.169 -170.958 221.316 1.00 75.61 ? 94 GLY L C 1 ATOM 4924 O O . GLY B 2 94 ? -154.774 -171.497 222.350 1.00 75.90 ? 94 GLY L O 1 ATOM 4925 N N . TYR B 2 95 ? -156.454 -170.731 221.074 1.00 77.72 ? 95 TYR L N 1 ATOM 4926 C CA . TYR B 2 95 ? -157.498 -171.307 221.916 1.00 70.33 ? 95 TYR L CA 1 ATOM 4927 C C . TYR B 2 95 ? -157.763 -172.760 221.535 1.00 66.29 ? 95 TYR L C 1 ATOM 4928 O O . TYR B 2 95 ? -157.751 -173.096 220.354 1.00 73.48 ? 95 TYR L O 1 ATOM 4929 C CB . TYR B 2 95 ? -158.780 -170.482 221.802 1.00 67.48 ? 95 TYR L CB 1 ATOM 4930 C CG . TYR B 2 95 ? -158.605 -169.015 222.181 1.00 72.26 ? 95 TYR L CG 1 ATOM 4931 C CD1 . TYR B 2 95 ? -158.819 -168.581 223.481 1.00 68.80 ? 95 TYR L CD1 1 ATOM 4932 C CD2 . TYR B 2 95 ? -158.225 -168.070 221.239 1.00 70.41 ? 95 TYR L CD2 1 ATOM 4933 C CE1 . TYR B 2 95 ? -158.660 -167.253 223.828 1.00 67.33 ? 95 TYR L CE1 1 ATOM 4934 C CE2 . TYR B 2 95 ? -158.076 -166.738 221.582 1.00 70.48 ? 95 TYR L CE2 1 ATOM 4935 C CZ . TYR B 2 95 ? -158.293 -166.336 222.880 1.00 70.70 ? 95 TYR L CZ 1 ATOM 4936 O OH . TYR B 2 95 ? -158.137 -165.009 223.232 1.00 76.18 ? 95 TYR L OH 1 ATOM 4937 N N . PRO B 2 96 ? -158.045 -173.628 222.521 1.00 75.53 ? 96 PRO L N 1 ATOM 4938 C CA . PRO B 2 96 ? -158.053 -173.351 223.965 1.00 76.60 ? 96 PRO L CA 1 ATOM 4939 C C . PRO B 2 96 ? -156.674 -173.042 224.533 1.00 75.25 ? 96 PRO L C 1 ATOM 4940 O O . PRO B 2 96 ? -155.713 -173.736 224.194 1.00 75.86 ? 96 PRO L O 1 ATOM 4941 C CB . PRO B 2 96 ? -158.598 -174.646 224.560 1.00 74.06 ? 96 PRO L CB 1 ATOM 4942 C CG . PRO B 2 96 ? -158.190 -175.705 223.586 1.00 73.25 ? 96 PRO L CG 1 ATOM 4943 C CD . PRO B 2 96 ? -158.221 -175.065 222.232 1.00 73.51 ? 96 PRO L CD 1 ATOM 4944 N N . LEU B 2 97 ? -156.592 -172.071 225.436 1.00 70.25 ? 97 LEU L N 1 ATOM 4945 C CA . LEU B 2 97 ? -155.342 -171.778 226.101 1.00 63.99 ? 97 LEU L CA 1 ATOM 4946 C C . LEU B 2 97 ? -154.954 -172.978 226.935 1.00 66.73 ? 97 LEU L C 1 ATOM 4947 O O . LEU B 2 97 ? -155.815 -173.592 227.554 1.00 71.44 ? 97 LEU L O 1 ATOM 4948 C CB . LEU B 2 97 ? -155.476 -170.546 226.980 1.00 70.16 ? 97 LEU L CB 1 ATOM 4949 C CG . LEU B 2 97 ? -156.085 -169.325 226.314 1.00 68.73 ? 97 LEU L CG 1 ATOM 4950 C CD1 . LEU B 2 97 ? -156.131 -168.169 227.307 1.00 64.55 ? 97 LEU L CD1 1 ATOM 4951 C CD2 . LEU B 2 97 ? -155.288 -168.981 225.074 1.00 67.12 ? 97 LEU L CD2 1 ATOM 4952 N N . THR B 2 98 ? -153.669 -173.315 226.980 1.00 72.21 ? 98 THR L N 1 ATOM 4953 C CA . THR B 2 98 ? -153.260 -174.490 227.745 1.00 71.99 ? 98 THR L CA 1 ATOM 4954 C C . THR B 2 98 ? -152.031 -174.263 228.625 1.00 69.50 ? 98 THR L C 1 ATOM 4955 O O . THR B 2 98 ? -151.115 -173.516 228.272 1.00 69.63 ? 98 THR L O 1 ATOM 4956 C CB . THR B 2 98 ? -152.994 -175.672 226.827 1.00 66.79 ? 98 THR L CB 1 ATOM 4957 O OG1 . THR B 2 98 ? -152.158 -175.249 225.754 1.00 69.91 ? 98 THR L OG1 1 ATOM 4958 C CG2 . THR B 2 98 ? -154.302 -176.195 226.269 1.00 68.43 ? 98 THR L CG2 1 ATOM 4959 N N . PHE B 2 99 ? -152.058 -174.904 229.793 1.00 70.13 ? 99 PHE L N 1 ATOM 4960 C CA . PHE B 2 99 ? -150.986 -174.822 230.771 1.00 64.02 ? 99 PHE L CA 1 ATOM 4961 C C . PHE B 2 99 ? -150.144 -176.078 230.736 1.00 63.59 ? 99 PHE L C 1 ATOM 4962 O O . PHE B 2 99 ? -150.644 -177.154 230.425 1.00 69.99 ? 99 PHE L O 1 ATOM 4963 C CB . PHE B 2 99 ? -151.557 -174.617 232.175 1.00 66.88 ? 99 PHE L CB 1 ATOM 4964 C CG . PHE B 2 99 ? -152.034 -173.232 232.435 1.00 64.12 ? 99 PHE L CG 1 ATOM 4965 C CD1 . PHE B 2 99 ? -153.178 -172.758 231.825 1.00 70.93 ? 99 PHE L CD1 1 ATOM 4966 C CD2 . PHE B 2 99 ? -151.337 -172.402 233.295 1.00 65.57 ? 99 PHE L CD2 1 ATOM 4967 C CE1 . PHE B 2 99 ? -153.604 -171.470 232.058 1.00 68.76 ? 99 PHE L CE1 1 ATOM 4968 C CE2 . PHE B 2 99 ? -151.753 -171.117 233.533 1.00 67.99 ? 99 PHE L CE2 1 ATOM 4969 C CZ . PHE B 2 99 ? -152.887 -170.651 232.917 1.00 66.08 ? 99 PHE L CZ 1 ATOM 4970 N N . GLY B 2 100 ? -148.870 -175.942 231.081 1.00 68.96 ? 100 GLY L N 1 ATOM 4971 C CA . GLY B 2 100 ? -147.972 -177.079 231.168 1.00 66.29 ? 100 GLY L CA 1 ATOM 4972 C C . GLY B 2 100 ? -148.256 -177.925 232.391 1.00 63.62 ? 100 GLY L C 1 ATOM 4973 O O . GLY B 2 100 ? -148.975 -177.513 233.295 1.00 69.77 ? 100 GLY L O 1 ATOM 4974 N N . SER B 2 101 ? -147.686 -179.117 232.420 1.00 60.87 ? 101 SER L N 1 ATOM 4975 C CA . SER B 2 101 ? -148.019 -180.111 233.424 1.00 56.42 ? 101 SER L CA 1 ATOM 4976 C C . SER B 2 101 ? -147.297 -179.886 234.751 1.00 61.57 ? 101 SER L C 1 ATOM 4977 O O . SER B 2 101 ? -147.517 -180.613 235.722 1.00 65.78 ? 101 SER L O 1 ATOM 4978 C CB . SER B 2 101 ? -147.691 -181.490 232.890 1.00 60.10 ? 101 SER L CB 1 ATOM 4979 O OG . SER B 2 101 ? -146.291 -181.581 232.602 1.00 73.71 ? 101 SER L OG 1 ATOM 4980 N N . GLY B 2 102 ? -146.415 -178.897 234.791 1.00 63.13 ? 102 GLY L N 1 ATOM 4981 C CA . GLY B 2 102 ? -145.751 -178.525 236.029 1.00 62.53 ? 102 GLY L CA 1 ATOM 4982 C C . GLY B 2 102 ? -144.379 -179.149 236.206 1.00 64.68 ? 102 GLY L C 1 ATOM 4983 O O . GLY B 2 102 ? -144.150 -180.295 235.835 1.00 69.04 ? 102 GLY L O 1 ATOM 4984 N N . THR B 2 103 ? -143.460 -178.369 236.760 1.00 64.11 ? 103 THR L N 1 ATOM 4985 C CA . THR B 2 103 ? -142.222 -178.885 237.328 1.00 65.66 ? 103 THR L CA 1 ATOM 4986 C C . THR B 2 103 ? -142.181 -178.428 238.778 1.00 64.77 ? 103 THR L C 1 ATOM 4987 O O . THR B 2 103 ? -142.076 -177.230 239.042 1.00 68.09 ? 103 THR L O 1 ATOM 4988 C CB . THR B 2 103 ? -140.962 -178.363 236.607 1.00 65.74 ? 103 THR L CB 1 ATOM 4989 O OG1 . THR B 2 103 ? -140.972 -178.767 235.233 1.00 67.11 ? 103 THR L OG1 1 ATOM 4990 C CG2 . THR B 2 103 ? -139.699 -178.876 237.293 1.00 61.91 ? 103 THR L CG2 1 ATOM 4991 N N . LYS B 2 104 ? -142.299 -179.359 239.715 1.00 65.73 ? 104 LYS L N 1 ATOM 4992 C CA . LYS B 2 104 ? -142.212 -178.994 241.126 1.00 71.92 ? 104 LYS L CA 1 ATOM 4993 C C . LYS B 2 104 ? -140.753 -178.936 241.557 1.00 71.29 ? 104 LYS L C 1 ATOM 4994 O O . LYS B 2 104 ? -140.032 -179.934 241.473 1.00 71.70 ? 104 LYS L O 1 ATOM 4995 C CB . LYS B 2 104 ? -142.995 -179.980 242.004 1.00 69.13 ? 104 LYS L CB 1 ATOM 4996 C CG . LYS B 2 104 ? -142.994 -179.621 243.472 1.00 65.82 ? 104 LYS L CG 1 ATOM 4997 C CD . LYS B 2 104 ? -143.420 -180.808 244.315 1.00 72.26 ? 104 LYS L CD 1 ATOM 4998 C CE . LYS B 2 104 ? -144.881 -180.684 244.740 1.00 86.45 ? 104 LYS L CE 1 ATOM 4999 N NZ . LYS B 2 104 ? -145.419 -181.955 245.316 1.00 88.25 ? 104 LYS L NZ 1 ATOM 5000 N N . LEU B 2 105 ? -140.326 -177.767 242.023 1.00 68.84 ? 105 LEU L N 1 ATOM 5001 C CA . LEU B 2 105 ? -138.944 -177.575 242.429 1.00 70.50 ? 105 LEU L CA 1 ATOM 5002 C C . LEU B 2 105 ? -138.828 -177.698 243.930 1.00 75.66 ? 105 LEU L C 1 ATOM 5003 O O . LEU B 2 105 ? -139.632 -177.115 244.669 1.00 78.95 ? 105 LEU L O 1 ATOM 5004 C CB . LEU B 2 105 ? -138.426 -176.218 241.982 1.00 73.16 ? 105 LEU L CB 1 ATOM 5005 C CG . LEU B 2 105 ? -137.005 -175.931 242.452 1.00 70.65 ? 105 LEU L CG 1 ATOM 5006 C CD1 . LEU B 2 105 ? -136.094 -177.047 241.981 1.00 71.72 ? 105 LEU L CD1 1 ATOM 5007 C CD2 . LEU B 2 105 ? -136.564 -174.603 241.914 1.00 64.88 ? 105 LEU L CD2 1 ATOM 5008 N N . GLU B 2 106 ? -137.809 -178.425 244.376 1.00 74.45 ? 106 GLU L N 1 ATOM 5009 C CA . GLU B 2 106 ? -137.682 -178.778 245.777 1.00 73.60 ? 106 GLU L CA 1 ATOM 5010 C C . GLU B 2 106 ? -136.251 -178.692 246.278 1.00 76.43 ? 106 GLU L C 1 ATOM 5011 O O . GLU B 2 106 ? -135.291 -178.858 245.524 1.00 75.45 ? 106 GLU L O 1 ATOM 5012 C CB . GLU B 2 106 ? -138.218 -180.180 246.011 1.00 76.40 ? 106 GLU L CB 1 ATOM 5013 C CG . GLU B 2 106 ? -139.713 -180.200 246.325 1.00 83.45 ? 106 GLU L CG 1 ATOM 5014 C CD . GLU B 2 106 ? -140.282 -181.606 246.486 1.00 86.67 ? 106 GLU L CD 1 ATOM 5015 O OE1 . GLU B 2 106 ? -139.734 -182.569 245.876 1.00 82.94 ? 106 GLU L OE1 1 ATOM 5016 O OE2 . GLU B 2 106 ? -141.286 -181.727 247.233 1.00 86.16 ? 106 GLU L OE2 1 ATOM 5017 N N . MET B 2 107 ? -136.113 -178.419 247.566 1.00 79.83 ? 107 MET L N 1 ATOM 5018 C CA . MET B 2 107 ? -134.800 -178.202 248.141 1.00 75.75 ? 107 MET L CA 1 ATOM 5019 C C . MET B 2 107 ? -134.128 -179.486 248.566 1.00 76.43 ? 107 MET L C 1 ATOM 5020 O O . MET B 2 107 ? -134.690 -180.268 249.323 1.00 77.06 ? 107 MET L O 1 ATOM 5021 C CB . MET B 2 107 ? -134.908 -177.262 249.334 1.00 73.15 ? 107 MET L CB 1 ATOM 5022 C CG . MET B 2 107 ? -135.164 -175.841 248.913 1.00 78.23 ? 107 MET L CG 1 ATOM 5023 S SD . MET B 2 107 ? -134.022 -175.374 247.605 1.00 81.90 ? 107 MET L SD 1 ATOM 5024 C CE . MET B 2 107 ? -135.106 -175.303 246.188 1.00 78.85 ? 107 MET L CE 1 ATOM 5025 N N . LYS B 2 108 ? -132.919 -179.706 248.073 1.00 79.11 ? 108 LYS L N 1 ATOM 5026 C CA . LYS B 2 108 ? -132.106 -180.783 248.610 1.00 80.78 ? 108 LYS L CA 1 ATOM 5027 C C . LYS B 2 108 ? -131.465 -180.334 249.927 1.00 82.02 ? 108 LYS L C 1 ATOM 5028 O O . LYS B 2 108 ? -131.190 -179.146 250.133 1.00 80.61 ? 108 LYS L O 1 ATOM 5029 C CB . LYS B 2 108 ? -131.040 -181.228 247.604 1.00 76.19 ? 108 LYS L CB 1 ATOM 5030 C CG . LYS B 2 108 ? -130.397 -182.543 247.952 1.00 70.96 ? 108 LYS L CG 1 ATOM 5031 C CD . LYS B 2 108 ? -129.206 -182.836 247.048 1.00 93.24 ? 108 LYS L CD 1 ATOM 5032 C CE . LYS B 2 108 ? -129.586 -182.853 245.565 1.00 94.60 ? 108 LYS L CE 1 ATOM 5033 N NZ . LYS B 2 108 ? -128.435 -183.305 244.718 1.00 108.46 ? 108 LYS L NZ 1 ATOM 5034 N N . ARG B 2 109 ? -131.217 -181.297 250.806 1.00 80.42 ? 109 ARG L N 1 ATOM 5035 C CA . ARG B 2 109 ? -130.624 -181.038 252.106 1.00 76.41 ? 109 ARG L CA 1 ATOM 5036 C C . ARG B 2 109 ? -130.003 -182.348 252.588 1.00 81.23 ? 109 ARG L C 1 ATOM 5037 O O . ARG B 2 109 ? -130.220 -183.397 251.973 1.00 82.32 ? 109 ARG L O 1 ATOM 5038 C CB . ARG B 2 109 ? -131.673 -180.537 253.092 1.00 74.91 ? 109 ARG L CB 1 ATOM 5039 C CG . ARG B 2 109 ? -132.526 -181.645 253.652 1.00 76.04 ? 109 ARG L CG 1 ATOM 5040 C CD . ARG B 2 109 ? -133.480 -181.141 254.691 1.00 80.75 ? 109 ARG L CD 1 ATOM 5041 N NE . ARG B 2 109 ? -132.849 -180.807 255.970 1.00 85.41 ? 109 ARG L NE 1 ATOM 5042 C CZ . ARG B 2 109 ? -132.437 -181.699 256.864 1.00 79.03 ? 109 ARG L CZ 1 ATOM 5043 N NH1 . ARG B 2 109 ? -132.542 -182.991 256.620 1.00 84.32 ? 109 ARG L NH1 1 ATOM 5044 N NH2 . ARG B 2 109 ? -131.906 -181.301 258.002 1.00 78.97 ? 109 ARG L NH2 1 ATOM 5045 N N . ALA B 2 110 ? -129.221 -182.305 253.662 1.00 82.86 ? 110 ALA L N 1 ATOM 5046 C CA . ALA B 2 110 ? -128.620 -183.531 254.188 1.00 75.09 ? 110 ALA L CA 1 ATOM 5047 C C . ALA B 2 110 ? -129.681 -184.416 254.822 1.00 78.89 ? 110 ALA L C 1 ATOM 5048 O O . ALA B 2 110 ? -130.650 -183.913 255.397 1.00 79.76 ? 110 ALA L O 1 ATOM 5049 C CB . ALA B 2 110 ? -127.531 -183.209 255.189 1.00 81.30 ? 110 ALA L CB 1 ATOM 5050 N N . ASP B 2 111 ? -129.470 -185.727 254.741 1.00 79.92 ? 111 ASP L N 1 ATOM 5051 C CA . ASP B 2 111 ? -130.433 -186.714 255.226 1.00 79.41 ? 111 ASP L CA 1 ATOM 5052 C C . ASP B 2 111 ? -130.738 -186.564 256.716 1.00 81.70 ? 111 ASP L C 1 ATOM 5053 O O . ASP B 2 111 ? -129.857 -186.247 257.517 1.00 83.85 ? 111 ASP L O 1 ATOM 5054 C CB . ASP B 2 111 ? -129.930 -188.143 254.957 1.00 80.29 ? 111 ASP L CB 1 ATOM 5055 C CG . ASP B 2 111 ? -129.848 -188.479 253.461 1.00 91.30 ? 111 ASP L CG 1 ATOM 5056 O OD1 . ASP B 2 111 ? -130.360 -187.692 252.627 1.00 90.53 ? 111 ASP L OD1 1 ATOM 5057 O OD2 . ASP B 2 111 ? -129.273 -189.543 253.119 1.00 90.50 ? 111 ASP L OD2 1 ATOM 5058 N N . ALA B 2 112 ? -131.995 -186.795 257.081 1.00 81.82 ? 112 ALA L N 1 ATOM 5059 C CA . ALA B 2 112 ? -132.401 -186.789 258.483 1.00 81.32 ? 112 ALA L CA 1 ATOM 5060 C C . ALA B 2 112 ? -133.396 -187.909 258.748 1.00 84.33 ? 112 ALA L C 1 ATOM 5061 O O . ALA B 2 112 ? -134.311 -188.128 257.958 1.00 89.06 ? 112 ALA L O 1 ATOM 5062 C CB . ALA B 2 112 ? -133.002 -185.451 258.854 1.00 79.35 ? 112 ALA L CB 1 ATOM 5063 N N . ALA B 2 113 ? -133.206 -188.628 259.847 1.00 83.77 ? 113 ALA L N 1 ATOM 5064 C CA . ALA B 2 113 ? -134.092 -189.727 260.196 1.00 79.87 ? 113 ALA L CA 1 ATOM 5065 C C . ALA B 2 113 ? -135.409 -189.241 260.799 1.00 84.27 ? 113 ALA L C 1 ATOM 5066 O O . ALA B 2 113 ? -135.459 -188.194 261.456 1.00 83.54 ? 113 ALA L O 1 ATOM 5067 C CB . ALA B 2 113 ? -133.400 -190.682 261.149 1.00 82.80 ? 113 ALA L CB 1 ATOM 5068 N N . PRO B 2 114 ? -136.491 -190.005 260.564 1.00 88.78 ? 114 PRO L N 1 ATOM 5069 C CA . PRO B 2 114 ? -137.815 -189.669 261.090 1.00 85.18 ? 114 PRO L CA 1 ATOM 5070 C C . PRO B 2 114 ? -137.843 -189.732 262.612 1.00 92.12 ? 114 PRO L C 1 ATOM 5071 O O . PRO B 2 114 ? -137.136 -190.558 263.196 1.00 89.02 ? 114 PRO L O 1 ATOM 5072 C CB . PRO B 2 114 ? -138.705 -190.742 260.483 1.00 82.23 ? 114 PRO L CB 1 ATOM 5073 C CG . PRO B 2 114 ? -137.795 -191.919 260.322 1.00 85.36 ? 114 PRO L CG 1 ATOM 5074 C CD . PRO B 2 114 ? -136.473 -191.332 259.923 1.00 89.42 ? 114 PRO L CD 1 ATOM 5075 N N . THR B 2 115 ? -138.651 -188.873 263.231 1.00 93.93 ? 115 THR L N 1 ATOM 5076 C CA . THR B 2 115 ? -138.986 -188.973 264.648 1.00 85.82 ? 115 THR L CA 1 ATOM 5077 C C . THR B 2 115 ? -140.343 -189.663 264.816 1.00 87.10 ? 115 THR L C 1 ATOM 5078 O O . THR B 2 115 ? -141.378 -189.004 264.945 1.00 90.17 ? 115 THR L O 1 ATOM 5079 C CB . THR B 2 115 ? -139.039 -187.575 265.311 1.00 87.79 ? 115 THR L CB 1 ATOM 5080 O OG1 . THR B 2 115 ? -137.808 -186.878 265.078 1.00 85.52 ? 115 THR L OG1 1 ATOM 5081 C CG2 . THR B 2 115 ? -139.294 -187.694 266.801 1.00 82.25 ? 115 THR L CG2 1 ATOM 5082 N N . VAL B 2 116 ? -140.338 -190.989 264.806 1.00 89.53 ? 116 VAL L N 1 ATOM 5083 C CA . VAL B 2 116 ? -141.569 -191.777 264.946 1.00 88.35 ? 116 VAL L CA 1 ATOM 5084 C C . VAL B 2 116 ? -142.256 -191.701 266.324 1.00 87.08 ? 116 VAL L C 1 ATOM 5085 O O . VAL B 2 116 ? -141.597 -191.738 267.356 1.00 91.63 ? 116 VAL L O 1 ATOM 5086 C CB . VAL B 2 116 ? -141.281 -193.253 264.642 1.00 84.92 ? 116 VAL L CB 1 ATOM 5087 C CG1 . VAL B 2 116 ? -142.533 -194.078 264.789 1.00 83.63 ? 116 VAL L CG1 1 ATOM 5088 C CG2 . VAL B 2 116 ? -140.680 -193.399 263.237 1.00 89.58 ? 116 VAL L CG2 1 ATOM 5089 N N . SER B 2 117 ? -143.587 -191.639 266.323 1.00 90.07 ? 117 SER L N 1 ATOM 5090 C CA . SER B 2 117 ? -144.398 -191.650 267.549 1.00 90.32 ? 117 SER L CA 1 ATOM 5091 C C . SER B 2 117 ? -145.676 -192.460 267.344 1.00 91.26 ? 117 SER L C 1 ATOM 5092 O O . SER B 2 117 ? -146.326 -192.330 266.309 1.00 96.07 ? 117 SER L O 1 ATOM 5093 C CB . SER B 2 117 ? -144.771 -190.229 267.968 1.00 80.97 ? 117 SER L CB 1 ATOM 5094 O OG . SER B 2 117 ? -143.682 -189.352 267.770 1.00 94.29 ? 117 SER L OG 1 ATOM 5095 N N . ILE B 2 118 ? -146.054 -193.284 268.318 1.00 92.17 ? 118 ILE L N 1 ATOM 5096 C CA . ILE B 2 118 ? -147.258 -194.093 268.154 1.00 91.80 ? 118 ILE L CA 1 ATOM 5097 C C . ILE B 2 118 ? -148.325 -193.761 269.182 1.00 95.78 ? 118 ILE L C 1 ATOM 5098 O O . ILE B 2 118 ? -148.033 -193.636 270.364 1.00 102.02 ? 118 ILE L O 1 ATOM 5099 C CB . ILE B 2 118 ? -146.956 -195.589 268.222 1.00 88.49 ? 118 ILE L CB 1 ATOM 5100 C CG1 . ILE B 2 118 ? -148.234 -196.373 267.924 1.00 90.01 ? 118 ILE L CG1 1 ATOM 5101 C CG2 . ILE B 2 118 ? -146.377 -195.958 269.571 1.00 89.30 ? 118 ILE L CG2 1 ATOM 5102 C CD1 . ILE B 2 118 ? -147.978 -197.748 267.333 1.00 94.89 ? 118 ILE L CD1 1 ATOM 5103 N N . PHE B 2 119 ? -149.561 -193.598 268.710 1.00 96.68 ? 119 PHE L N 1 ATOM 5104 C CA . PHE B 2 119 ? -150.689 -193.195 269.552 1.00 96.23 ? 119 PHE L CA 1 ATOM 5105 C C . PHE B 2 119 ? -151.854 -194.200 269.530 1.00 97.20 ? 119 PHE L C 1 ATOM 5106 O O . PHE B 2 119 ? -152.419 -194.473 268.474 1.00 95.99 ? 119 PHE L O 1 ATOM 5107 C CB . PHE B 2 119 ? -151.198 -191.820 269.122 1.00 91.08 ? 119 PHE L CB 1 ATOM 5108 C CG . PHE B 2 119 ? -150.178 -190.731 269.234 1.00 96.50 ? 119 PHE L CG 1 ATOM 5109 C CD1 . PHE B 2 119 ? -149.030 -190.905 269.979 1.00 107.06 ? 119 PHE L CD1 1 ATOM 5110 C CD2 . PHE B 2 119 ? -150.376 -189.525 268.605 1.00 104.15 ? 119 PHE L CD2 1 ATOM 5111 C CE1 . PHE B 2 119 ? -148.087 -189.899 270.085 1.00 107.37 ? 119 PHE L CE1 1 ATOM 5112 C CE2 . PHE B 2 119 ? -149.442 -188.510 268.714 1.00 108.91 ? 119 PHE L CE2 1 ATOM 5113 C CZ . PHE B 2 119 ? -148.297 -188.698 269.454 1.00 101.77 ? 119 PHE L CZ 1 ATOM 5114 N N . PRO B 2 120 ? -152.200 -194.766 270.698 1.00 103.17 ? 120 PRO L N 1 ATOM 5115 C CA . PRO B 2 120 ? -153.351 -195.653 270.911 1.00 97.63 ? 120 PRO L CA 1 ATOM 5116 C C . PRO B 2 120 ? -154.655 -194.895 270.736 1.00 93.26 ? 120 PRO L C 1 ATOM 5117 O O . PRO B 2 120 ? -154.644 -193.674 270.865 1.00 96.36 ? 120 PRO L O 1 ATOM 5118 C CB . PRO B 2 120 ? -153.181 -196.120 272.358 1.00 100.59 ? 120 PRO L CB 1 ATOM 5119 C CG . PRO B 2 120 ? -151.765 -195.861 272.689 1.00 103.50 ? 120 PRO L CG 1 ATOM 5120 C CD . PRO B 2 120 ? -151.401 -194.624 271.924 1.00 103.30 ? 120 PRO L CD 1 ATOM 5121 N N . PRO B 2 121 ? -155.757 -195.606 270.446 1.00 93.54 ? 121 PRO L N 1 ATOM 5122 C CA . PRO B 2 121 ? -157.029 -194.909 270.233 1.00 94.40 ? 121 PRO L CA 1 ATOM 5123 C C . PRO B 2 121 ? -157.472 -194.154 271.477 1.00 94.12 ? 121 PRO L C 1 ATOM 5124 O O . PRO B 2 121 ? -157.259 -194.621 272.590 1.00 96.93 ? 121 PRO L O 1 ATOM 5125 C CB . PRO B 2 121 ? -158.004 -196.056 269.934 1.00 87.84 ? 121 PRO L CB 1 ATOM 5126 C CG . PRO B 2 121 ? -157.146 -197.193 269.482 1.00 89.21 ? 121 PRO L CG 1 ATOM 5127 C CD . PRO B 2 121 ? -155.871 -197.058 270.247 1.00 93.15 ? 121 PRO L CD 1 ATOM 5128 N N . SER B 2 122 ? -158.076 -192.988 271.273 1.00 94.18 ? 122 SER L N 1 ATOM 5129 C CA . SER B 2 122 ? -158.556 -192.175 272.381 1.00 101.20 ? 122 SER L CA 1 ATOM 5130 C C . SER B 2 122 ? -159.836 -192.778 272.957 1.00 104.76 ? 122 SER L C 1 ATOM 5131 O O . SER B 2 122 ? -160.608 -193.410 272.230 1.00 103.56 ? 122 SER L O 1 ATOM 5132 C CB . SER B 2 122 ? -158.805 -190.730 271.934 1.00 98.85 ? 122 SER L CB 1 ATOM 5133 O OG . SER B 2 122 ? -160.076 -190.597 271.322 1.00 98.62 ? 122 SER L OG 1 ATOM 5134 N N . SER B 2 123 ? -160.079 -192.564 274.248 1.00 103.61 ? 123 SER L N 1 ATOM 5135 C CA . SER B 2 123 ? -161.249 -193.148 274.883 1.00 104.77 ? 123 SER L CA 1 ATOM 5136 C C . SER B 2 123 ? -162.534 -192.634 274.245 1.00 105.47 ? 123 SER L C 1 ATOM 5137 O O . SER B 2 123 ? -163.538 -193.350 274.199 1.00 105.56 ? 123 SER L O 1 ATOM 5138 C CB . SER B 2 123 ? -161.251 -192.859 276.384 1.00 113.64 ? 123 SER L CB 1 ATOM 5139 O OG . SER B 2 123 ? -160.244 -193.611 277.044 1.00 125.20 ? 123 SER L OG 1 ATOM 5140 N N . GLU B 2 124 ? -162.501 -191.403 273.740 1.00 102.24 ? 124 GLU L N 1 ATOM 5141 C CA . GLU B 2 124 ? -163.667 -190.834 273.074 1.00 99.78 ? 124 GLU L CA 1 ATOM 5142 C C . GLU B 2 124 ? -164.010 -191.633 271.819 1.00 101.05 ? 124 GLU L C 1 ATOM 5143 O O . GLU B 2 124 ? -165.179 -191.756 271.447 1.00 101.73 ? 124 GLU L O 1 ATOM 5144 C CB . GLU B 2 124 ? -163.433 -189.364 272.708 1.00 100.72 ? 124 GLU L CB 1 ATOM 5145 C CG . GLU B 2 124 ? -163.205 -188.426 273.890 1.00 101.64 ? 124 GLU L CG 1 ATOM 5146 C CD . GLU B 2 124 ? -161.763 -188.422 274.394 1.00 106.91 ? 124 GLU L CD 1 ATOM 5147 O OE1 . GLU B 2 124 ? -161.069 -189.467 274.312 1.00 103.45 ? 124 GLU L OE1 1 ATOM 5148 O OE2 . GLU B 2 124 ? -161.325 -187.352 274.870 1.00 112.32 ? 124 GLU L OE2 1 ATOM 5149 N N . GLN B 2 125 ? -162.989 -192.190 271.170 1.00 99.96 ? 125 GLN L N 1 ATOM 5150 C CA . GLN B 2 125 ? -163.217 -192.933 269.939 1.00 98.13 ? 125 GLN L CA 1 ATOM 5151 C C . GLN B 2 125 ? -163.699 -194.353 270.200 1.00 98.31 ? 125 GLN L C 1 ATOM 5152 O O . GLN B 2 125 ? -164.577 -194.852 269.484 1.00 96.19 ? 125 GLN L O 1 ATOM 5153 C CB . GLN B 2 125 ? -161.952 -192.982 269.075 1.00 99.31 ? 125 GLN L CB 1 ATOM 5154 C CG . GLN B 2 125 ? -162.246 -193.377 267.627 1.00 91.84 ? 125 GLN L CG 1 ATOM 5155 C CD . GLN B 2 125 ? -161.024 -193.810 266.850 1.00 88.92 ? 125 GLN L CD 1 ATOM 5156 O OE1 . GLN B 2 125 ? -159.914 -193.884 267.386 1.00 90.50 ? 125 GLN L OE1 1 ATOM 5157 N NE2 . GLN B 2 125 ? -161.225 -194.109 265.570 1.00 83.71 ? 125 GLN L NE2 1 ATOM 5158 N N . LEU B 2 126 ? -163.133 -195.004 271.218 1.00 97.62 ? 126 LEU L N 1 ATOM 5159 C CA . LEU B 2 126 ? -163.509 -196.386 271.509 1.00 98.12 ? 126 LEU L CA 1 ATOM 5160 C C . LEU B 2 126 ? -164.982 -196.463 271.900 1.00 98.92 ? 126 LEU L C 1 ATOM 5161 O O . LEU B 2 126 ? -165.674 -197.408 271.535 1.00 96.31 ? 126 LEU L O 1 ATOM 5162 C CB . LEU B 2 126 ? -162.634 -196.967 272.629 1.00 99.23 ? 126 LEU L CB 1 ATOM 5163 C CG . LEU B 2 126 ? -161.204 -197.422 272.312 1.00 96.73 ? 126 LEU L CG 1 ATOM 5164 C CD1 . LEU B 2 126 ? -160.384 -196.249 271.866 1.00 105.73 ? 126 LEU L CD1 1 ATOM 5165 C CD2 . LEU B 2 126 ? -160.531 -198.075 273.502 1.00 93.77 ? 126 LEU L CD2 1 ATOM 5166 N N . THR B 2 127 ? -165.460 -195.439 272.602 1.00 101.06 ? 127 THR L N 1 ATOM 5167 C CA . THR B 2 127 ? -166.858 -195.380 273.017 1.00 100.47 ? 127 THR L CA 1 ATOM 5168 C C . THR B 2 127 ? -167.770 -195.176 271.815 1.00 99.92 ? 127 THR L C 1 ATOM 5169 O O . THR B 2 127 ? -168.958 -195.489 271.866 1.00 100.87 ? 127 THR L O 1 ATOM 5170 C CB . THR B 2 127 ? -167.114 -194.249 274.034 1.00 104.39 ? 127 THR L CB 1 ATOM 5171 O OG1 . THR B 2 127 ? -167.079 -192.985 273.364 1.00 109.84 ? 127 THR L OG1 1 ATOM 5172 C CG2 . THR B 2 127 ? -166.077 -194.276 275.160 1.00 98.45 ? 127 THR L CG2 1 ATOM 5173 N N . SER B 2 128 ? -167.202 -194.629 270.742 1.00 104.00 ? 128 SER L N 1 ATOM 5174 C CA . SER B 2 128 ? -167.914 -194.446 269.474 1.00 102.50 ? 128 SER L CA 1 ATOM 5175 C C . SER B 2 128 ? -168.098 -195.765 268.715 1.00 95.89 ? 128 SER L C 1 ATOM 5176 O O . SER B 2 128 ? -168.908 -195.848 267.792 1.00 97.18 ? 128 SER L O 1 ATOM 5177 C CB . SER B 2 128 ? -167.174 -193.430 268.591 1.00 99.34 ? 128 SER L CB 1 ATOM 5178 N N . GLY B 2 129 ? -167.353 -196.792 269.121 1.00 95.68 ? 129 GLY L N 1 ATOM 5179 C CA . GLY B 2 129 ? -167.313 -198.060 268.411 1.00 93.87 ? 129 GLY L CA 1 ATOM 5180 C C . GLY B 2 129 ? -166.123 -198.185 267.468 1.00 101.16 ? 129 GLY L C 1 ATOM 5181 O O . GLY B 2 129 ? -165.910 -199.233 266.846 1.00 103.03 ? 129 GLY L O 1 ATOM 5182 N N . GLY B 2 130 ? -165.353 -197.108 267.344 1.00 97.12 ? 130 GLY L N 1 ATOM 5183 C CA . GLY B 2 130 ? -164.180 -197.107 266.491 1.00 94.19 ? 130 GLY L CA 1 ATOM 5184 C C . GLY B 2 130 ? -162.873 -197.333 267.224 1.00 95.10 ? 130 GLY L C 1 ATOM 5185 O O . GLY B 2 130 ? -162.838 -197.424 268.449 1.00 100.69 ? 130 GLY L O 1 ATOM 5186 N N . ALA B 2 131 ? -161.788 -197.415 266.463 1.00 92.10 ? 131 ALA L N 1 ATOM 5187 C CA . ALA B 2 131 ? -160.451 -197.526 267.028 1.00 90.54 ? 131 ALA L CA 1 ATOM 5188 C C . ALA B 2 131 ? -159.419 -197.280 265.943 1.00 91.28 ? 131 ALA L C 1 ATOM 5189 O O . ALA B 2 131 ? -159.198 -198.147 265.096 1.00 88.88 ? 131 ALA L O 1 ATOM 5190 C CB . ALA B 2 131 ? -160.237 -198.895 267.655 1.00 91.43 ? 131 ALA L CB 1 ATOM 5191 N N . SER B 2 132 ? -158.789 -196.107 265.954 1.00 85.22 ? 132 SER L N 1 ATOM 5192 C CA . SER B 2 132 ? -157.689 -195.883 265.033 1.00 84.95 ? 132 SER L CA 1 ATOM 5193 C C . SER B 2 132 ? -156.409 -195.537 265.784 1.00 85.92 ? 132 SER L C 1 ATOM 5194 O O . SER B 2 132 ? -156.327 -194.536 266.502 1.00 87.51 ? 132 SER L O 1 ATOM 5195 C CB . SER B 2 132 ? -158.037 -194.798 264.005 1.00 85.10 ? 132 SER L CB 1 ATOM 5196 O OG . SER B 2 132 ? -158.697 -193.701 264.598 1.00 88.33 ? 132 SER L OG 1 ATOM 5197 N N . VAL B 2 133 ? -155.431 -196.425 265.647 1.00 84.31 ? 133 VAL L N 1 ATOM 5198 C CA . VAL B 2 133 ? -154.064 -196.162 266.062 1.00 84.62 ? 133 VAL L CA 1 ATOM 5199 C C . VAL B 2 133 ? -153.456 -195.141 265.094 1.00 87.16 ? 133 VAL L C 1 ATOM 5200 O O . VAL B 2 133 ? -153.792 -195.133 263.911 1.00 88.85 ? 133 VAL L O 1 ATOM 5201 C CB . VAL B 2 133 ? -153.217 -197.451 266.075 1.00 86.44 ? 133 VAL L CB 1 ATOM 5202 C CG1 . VAL B 2 133 ? -151.933 -197.240 266.860 1.00 89.23 ? 133 VAL L CG1 1 ATOM 5203 C CG2 . VAL B 2 133 ? -154.019 -198.621 266.647 1.00 83.94 ? 133 VAL L CG2 1 ATOM 5204 N N . VAL B 2 134 ? -152.574 -194.278 265.585 1.00 86.57 ? 134 VAL L N 1 ATOM 5205 C CA . VAL B 2 134 ? -151.930 -193.282 264.737 1.00 80.88 ? 134 VAL L CA 1 ATOM 5206 C C . VAL B 2 134 ? -150.431 -193.284 264.975 1.00 84.18 ? 134 VAL L C 1 ATOM 5207 O O . VAL B 2 134 ? -149.974 -193.523 266.079 1.00 88.69 ? 134 VAL L O 1 ATOM 5208 C CB . VAL B 2 134 ? -152.496 -191.869 264.989 1.00 76.54 ? 134 VAL L CB 1 ATOM 5209 C CG1 . VAL B 2 134 ? -151.673 -190.808 264.268 1.00 78.28 ? 134 VAL L CG1 1 ATOM 5210 C CG2 . VAL B 2 134 ? -153.941 -191.807 264.554 1.00 82.52 ? 134 VAL L CG2 1 ATOM 5211 N N . CYS B 2 135 ? -149.663 -193.023 263.928 1.00 86.45 ? 135 CYS L N 1 ATOM 5212 C CA . CYS B 2 135 ? -148.222 -193.013 264.044 1.00 81.18 ? 135 CYS L CA 1 ATOM 5213 C C . CYS B 2 135 ? -147.624 -191.888 263.218 1.00 87.15 ? 135 CYS L C 1 ATOM 5214 O O . CYS B 2 135 ? -147.511 -192.004 261.996 1.00 88.61 ? 135 CYS L O 1 ATOM 5215 C CB . CYS B 2 135 ? -147.656 -194.358 263.610 1.00 86.09 ? 135 CYS L CB 1 ATOM 5216 S SG . CYS B 2 135 ? -145.866 -194.371 263.493 1.00 100.27 ? 135 CYS L SG 1 ATOM 5217 N N . PHE B 2 136 ? -147.299 -190.781 263.882 1.00 82.26 ? 136 PHE L N 1 ATOM 5218 C CA . PHE B 2 136 ? -146.586 -189.679 263.246 1.00 81.63 ? 136 PHE L CA 1 ATOM 5219 C C . PHE B 2 136 ? -145.122 -190.019 262.934 1.00 83.75 ? 136 PHE L C 1 ATOM 5220 O O . PHE B 2 136 ? -144.439 -190.649 263.734 1.00 87.26 ? 136 PHE L O 1 ATOM 5221 C CB . PHE B 2 136 ? -146.661 -188.443 264.135 1.00 83.00 ? 136 PHE L CB 1 ATOM 5222 C CG . PHE B 2 136 ? -148.055 -187.946 264.357 1.00 85.88 ? 136 PHE L CG 1 ATOM 5223 C CD1 . PHE B 2 136 ? -148.884 -187.685 263.281 1.00 88.03 ? 136 PHE L CD1 1 ATOM 5224 C CD2 . PHE B 2 136 ? -148.543 -187.738 265.634 1.00 91.55 ? 136 PHE L CD2 1 ATOM 5225 C CE1 . PHE B 2 136 ? -150.179 -187.226 263.472 1.00 88.33 ? 136 PHE L CE1 1 ATOM 5226 C CE2 . PHE B 2 136 ? -149.842 -187.281 265.836 1.00 93.34 ? 136 PHE L CE2 1 ATOM 5227 C CZ . PHE B 2 136 ? -150.659 -187.027 264.756 1.00 91.75 ? 136 PHE L CZ 1 ATOM 5228 N N . LEU B 2 137 ? -144.642 -189.579 261.779 1.00 80.32 ? 137 LEU L N 1 ATOM 5229 C CA . LEU B 2 137 ? -143.247 -189.739 261.397 1.00 76.80 ? 137 LEU L CA 1 ATOM 5230 C C . LEU B 2 137 ? -142.733 -188.383 260.964 1.00 83.67 ? 137 LEU L C 1 ATOM 5231 O O . LEU B 2 137 ? -142.955 -187.973 259.820 1.00 86.78 ? 137 LEU L O 1 ATOM 5232 C CB . LEU B 2 137 ? -143.089 -190.745 260.261 1.00 76.98 ? 137 LEU L CB 1 ATOM 5233 C CG . LEU B 2 137 ? -143.347 -192.219 260.553 1.00 79.50 ? 137 LEU L CG 1 ATOM 5234 C CD1 . LEU B 2 137 ? -144.784 -192.430 260.973 1.00 81.27 ? 137 LEU L CD1 1 ATOM 5235 C CD2 . LEU B 2 137 ? -143.027 -193.053 259.328 1.00 83.37 ? 137 LEU L CD2 1 ATOM 5236 N N . ASN B 2 138 ? -142.048 -187.681 261.863 1.00 83.60 ? 138 ASN L N 1 ATOM 5237 C CA . ASN B 2 138 ? -141.754 -186.269 261.627 1.00 81.92 ? 138 ASN L CA 1 ATOM 5238 C C . ASN B 2 138 ? -140.312 -185.897 261.270 1.00 86.56 ? 138 ASN L C 1 ATOM 5239 O O . ASN B 2 138 ? -139.341 -186.528 261.706 1.00 89.46 ? 138 ASN L O 1 ATOM 5240 C CB . ASN B 2 138 ? -142.187 -185.469 262.847 1.00 80.97 ? 138 ASN L CB 1 ATOM 5241 C CG . ASN B 2 138 ? -143.689 -185.486 263.030 1.00 85.92 ? 138 ASN L CG 1 ATOM 5242 O OD1 . ASN B 2 138 ? -144.435 -185.373 262.062 1.00 88.89 ? 138 ASN L OD1 1 ATOM 5243 N ND2 . ASN B 2 138 ? -144.143 -185.647 264.267 1.00 83.66 ? 138 ASN L ND2 1 ATOM 5244 N N . ASN B 2 139 ? -140.199 -184.855 260.452 1.00 84.79 ? 139 ASN L N 1 ATOM 5245 C CA . ASN B 2 139 ? -138.935 -184.185 260.203 1.00 80.96 ? 139 ASN L CA 1 ATOM 5246 C C . ASN B 2 139 ? -137.818 -185.079 259.674 1.00 84.58 ? 139 ASN L C 1 ATOM 5247 O O . ASN B 2 139 ? -136.747 -185.176 260.289 1.00 87.73 ? 139 ASN L O 1 ATOM 5248 C CB . ASN B 2 139 ? -138.484 -183.502 261.489 1.00 83.13 ? 139 ASN L CB 1 ATOM 5249 C CG . ASN B 2 139 ? -139.539 -182.561 262.045 1.00 82.71 ? 139 ASN L CG 1 ATOM 5250 O OD1 . ASN B 2 139 ? -139.803 -181.502 261.476 1.00 84.34 ? 139 ASN L OD1 1 ATOM 5251 N ND2 . ASN B 2 139 ? -140.145 -182.942 263.164 1.00 86.17 ? 139 ASN L ND2 1 ATOM 5252 N N . PHE B 2 140 ? -138.072 -185.720 258.532 1.00 78.63 ? 140 PHE L N 1 ATOM 5253 C CA . PHE B 2 140 ? -137.064 -186.542 257.862 1.00 76.58 ? 140 PHE L CA 1 ATOM 5254 C C . PHE B 2 140 ? -136.785 -186.063 256.440 1.00 75.37 ? 140 PHE L C 1 ATOM 5255 O O . PHE B 2 140 ? -137.525 -185.247 255.895 1.00 77.39 ? 140 PHE L O 1 ATOM 5256 C CB . PHE B 2 140 ? -137.493 -188.012 257.843 1.00 80.04 ? 140 PHE L CB 1 ATOM 5257 C CG . PHE B 2 140 ? -138.793 -188.263 257.129 1.00 79.38 ? 140 PHE L CG 1 ATOM 5258 C CD1 . PHE B 2 140 ? -138.817 -188.529 255.770 1.00 78.74 ? 140 PHE L CD1 1 ATOM 5259 C CD2 . PHE B 2 140 ? -139.994 -188.238 257.819 1.00 80.17 ? 140 PHE L CD2 1 ATOM 5260 C CE1 . PHE B 2 140 ? -140.014 -188.762 255.116 1.00 76.20 ? 140 PHE L CE1 1 ATOM 5261 C CE2 . PHE B 2 140 ? -141.191 -188.476 257.172 1.00 76.66 ? 140 PHE L CE2 1 ATOM 5262 C CZ . PHE B 2 140 ? -141.198 -188.739 255.819 1.00 77.73 ? 140 PHE L CZ 1 ATOM 5263 N N . TYR B 2 141 ? -135.675 -186.542 255.882 1.00 78.73 ? 141 TYR L N 1 ATOM 5264 C CA . TYR B 2 141 ? -135.298 -186.318 254.487 1.00 78.76 ? 141 TYR L CA 1 ATOM 5265 C C . TYR B 2 141 ? -134.429 -187.492 254.033 1.00 81.05 ? 141 TYR L C 1 ATOM 5266 O O . TYR B 2 141 ? -133.641 -188.000 254.819 1.00 83.06 ? 141 TYR L O 1 ATOM 5267 C CB . TYR B 2 141 ? -134.542 -184.998 254.326 1.00 75.29 ? 141 TYR L CB 1 ATOM 5268 C CG . TYR B 2 141 ? -134.269 -184.646 252.888 1.00 79.32 ? 141 TYR L CG 1 ATOM 5269 C CD1 . TYR B 2 141 ? -135.105 -183.795 252.188 1.00 73.91 ? 141 TYR L CD1 1 ATOM 5270 C CD2 . TYR B 2 141 ? -133.181 -185.183 252.220 1.00 79.67 ? 141 TYR L CD2 1 ATOM 5271 C CE1 . TYR B 2 141 ? -134.851 -183.488 250.867 1.00 76.55 ? 141 TYR L CE1 1 ATOM 5272 C CE2 . TYR B 2 141 ? -132.932 -184.886 250.905 1.00 72.15 ? 141 TYR L CE2 1 ATOM 5273 C CZ . TYR B 2 141 ? -133.758 -184.044 250.230 1.00 76.37 ? 141 TYR L CZ 1 ATOM 5274 O OH . TYR B 2 141 ? -133.486 -183.758 248.904 1.00 83.47 ? 141 TYR L OH 1 ATOM 5275 N N . PRO B 2 142 ? -134.557 -187.940 252.774 1.00 81.82 ? 142 PRO L N 1 ATOM 5276 C CA . PRO B 2 142 ? -135.425 -187.515 251.670 1.00 82.97 ? 142 PRO L CA 1 ATOM 5277 C C . PRO B 2 142 ? -136.868 -187.947 251.866 1.00 79.98 ? 142 PRO L C 1 ATOM 5278 O O . PRO B 2 142 ? -137.159 -188.659 252.841 1.00 73.61 ? 142 PRO L O 1 ATOM 5279 C CB . PRO B 2 142 ? -134.819 -188.225 250.463 1.00 80.37 ? 142 PRO L CB 1 ATOM 5280 C CG . PRO B 2 142 ? -134.313 -189.482 251.031 1.00 82.72 ? 142 PRO L CG 1 ATOM 5281 C CD . PRO B 2 142 ? -133.735 -189.093 252.376 1.00 84.42 ? 142 PRO L CD 1 ATOM 5282 N N . LYS B 2 143 ? -137.745 -187.528 250.950 1.00 80.09 ? 143 LYS L N 1 ATOM 5283 C CA . LYS B 2 143 ? -139.188 -187.661 251.156 1.00 79.59 ? 143 LYS L CA 1 ATOM 5284 C C . LYS B 2 143 ? -139.666 -189.098 251.267 1.00 76.46 ? 143 LYS L C 1 ATOM 5285 O O . LYS B 2 143 ? -140.571 -189.389 252.040 1.00 79.07 ? 143 LYS L O 1 ATOM 5286 C CB . LYS B 2 143 ? -139.951 -186.980 250.019 1.00 77.22 ? 143 LYS L CB 1 ATOM 5287 C CG . LYS B 2 143 ? -141.466 -186.937 250.236 1.00 80.95 ? 143 LYS L CG 1 ATOM 5288 C CD . LYS B 2 143 ? -142.153 -185.943 249.289 1.00 80.42 ? 143 LYS L CD 1 ATOM 5289 C CE . LYS B 2 143 ? -143.671 -185.982 249.418 1.00 72.72 ? 143 LYS L CE 1 ATOM 5290 N NZ . LYS B 2 143 ? -144.296 -186.767 248.312 1.00 91.00 ? 143 LYS L NZ 1 ATOM 5291 N N . ASP B 2 144 ? -139.048 -190.006 250.522 1.00 79.94 ? 144 ASP L N 1 ATOM 5292 C CA . ASP B 2 144 ? -139.528 -191.381 250.523 1.00 82.21 ? 144 ASP L CA 1 ATOM 5293 C C . ASP B 2 144 ? -139.360 -192.030 251.903 1.00 82.38 ? 144 ASP L C 1 ATOM 5294 O O . ASP B 2 144 ? -138.265 -192.027 252.479 1.00 84.13 ? 144 ASP L O 1 ATOM 5295 C CB . ASP B 2 144 ? -138.797 -192.191 249.442 1.00 80.30 ? 144 ASP L CB 1 ATOM 5296 C CG . ASP B 2 144 ? -139.266 -193.639 249.369 1.00 87.93 ? 144 ASP L CG 1 ATOM 5297 O OD1 . ASP B 2 144 ? -140.374 -193.881 248.826 1.00 91.09 ? 144 ASP L OD1 1 ATOM 5298 O OD2 . ASP B 2 144 ? -138.525 -194.536 249.850 1.00 85.72 ? 144 ASP L OD2 1 ATOM 5299 N N . ILE B 2 145 ? -140.433 -192.653 252.380 1.00 76.69 ? 145 ILE L N 1 ATOM 5300 C CA . ILE B 2 145 ? -140.416 -193.396 253.629 1.00 79.74 ? 145 ILE L CA 1 ATOM 5301 C C . ILE B 2 145 ? -141.514 -194.452 253.574 1.00 85.26 ? 145 ILE L C 1 ATOM 5302 O O . ILE B 2 145 ? -142.508 -194.271 252.867 1.00 82.20 ? 145 ILE L O 1 ATOM 5303 C CB . ILE B 2 145 ? -140.623 -192.477 254.849 1.00 82.94 ? 145 ILE L CB 1 ATOM 5304 C CG1 . ILE B 2 145 ? -140.194 -193.187 256.135 1.00 84.85 ? 145 ILE L CG1 1 ATOM 5305 C CG2 . ILE B 2 145 ? -142.067 -192.019 254.933 1.00 81.24 ? 145 ILE L CG2 1 ATOM 5306 C CD1 . ILE B 2 145 ? -140.270 -192.321 257.368 1.00 80.93 ? 145 ILE L CD1 1 ATOM 5307 N N . ASN B 2 146 ? -141.332 -195.547 254.313 1.00 88.22 ? 146 ASN L N 1 ATOM 5308 C CA . ASN B 2 146 ? -142.246 -196.690 254.253 1.00 77.14 ? 146 ASN L CA 1 ATOM 5309 C C . ASN B 2 146 ? -142.688 -197.174 255.627 1.00 83.52 ? 146 ASN L C 1 ATOM 5310 O O . ASN B 2 146 ? -141.915 -197.794 256.354 1.00 89.82 ? 146 ASN L O 1 ATOM 5311 C CB . ASN B 2 146 ? -141.592 -197.843 253.496 1.00 80.02 ? 146 ASN L CB 1 ATOM 5312 C CG . ASN B 2 146 ? -141.223 -197.470 252.070 1.00 89.01 ? 146 ASN L CG 1 ATOM 5313 O OD1 . ASN B 2 146 ? -140.046 -197.222 251.764 1.00 88.70 ? 146 ASN L OD1 1 ATOM 5314 N ND2 . ASN B 2 146 ? -142.231 -197.417 251.184 1.00 83.05 ? 146 ASN L ND2 1 ATOM 5315 N N . VAL B 2 147 ? -143.926 -196.860 255.994 1.00 85.30 ? 147 VAL L N 1 ATOM 5316 C CA . VAL B 2 147 ? -144.481 -197.302 257.266 1.00 83.98 ? 147 VAL L CA 1 ATOM 5317 C C . VAL B 2 147 ? -145.004 -198.720 257.132 1.00 84.13 ? 147 VAL L C 1 ATOM 5318 O O . VAL B 2 147 ? -145.373 -199.143 256.044 1.00 86.72 ? 147 VAL L O 1 ATOM 5319 C CB . VAL B 2 147 ? -145.604 -196.368 257.755 1.00 85.52 ? 147 VAL L CB 1 ATOM 5320 C CG1 . VAL B 2 147 ? -146.693 -196.271 256.700 1.00 90.24 ? 147 VAL L CG1 1 ATOM 5321 C CG2 . VAL B 2 147 ? -146.180 -196.875 259.069 1.00 85.09 ? 147 VAL L CG2 1 ATOM 5322 N N . LYS B 2 148 ? -145.031 -199.449 258.242 1.00 91.06 ? 148 LYS L N 1 ATOM 5323 C CA . LYS B 2 148 ? -145.475 -200.842 258.262 1.00 88.12 ? 148 LYS L CA 1 ATOM 5324 C C . LYS B 2 148 ? -146.106 -201.194 259.617 1.00 91.37 ? 148 LYS L C 1 ATOM 5325 O O . LYS B 2 148 ? -145.420 -201.195 260.636 1.00 100.97 ? 148 LYS L O 1 ATOM 5326 C CB . LYS B 2 148 ? -144.292 -201.768 257.962 1.00 89.18 ? 148 LYS L CB 1 ATOM 5327 C CG . LYS B 2 148 ? -144.562 -203.251 258.172 1.00 94.28 ? 148 LYS L CG 1 ATOM 5328 C CD . LYS B 2 148 ? -143.270 -204.071 258.078 1.00 92.57 ? 148 LYS L CD 1 ATOM 5329 C CE . LYS B 2 148 ? -142.909 -204.406 256.635 1.00 89.40 ? 148 LYS L CE 1 ATOM 5330 N NZ . LYS B 2 148 ? -141.608 -205.138 256.519 1.00 97.62 ? 148 LYS L NZ 1 ATOM 5331 N N . TRP B 2 149 ? -147.411 -201.449 259.644 1.00 87.23 ? 149 TRP L N 1 ATOM 5332 C CA . TRP B 2 149 ? -148.088 -201.773 260.900 1.00 87.50 ? 149 TRP L CA 1 ATOM 5333 C C . TRP B 2 149 ? -148.025 -203.258 261.253 1.00 93.79 ? 149 TRP L C 1 ATOM 5334 O O . TRP B 2 149 ? -148.058 -204.121 260.370 1.00 91.94 ? 149 TRP L O 1 ATOM 5335 C CB . TRP B 2 149 ? -149.554 -201.345 260.848 1.00 90.19 ? 149 TRP L CB 1 ATOM 5336 C CG . TRP B 2 149 ? -149.774 -199.870 260.811 1.00 84.92 ? 149 TRP L CG 1 ATOM 5337 C CD1 . TRP B 2 149 ? -149.895 -199.093 259.702 1.00 84.35 ? 149 TRP L CD1 1 ATOM 5338 C CD2 . TRP B 2 149 ? -149.918 -198.992 261.934 1.00 90.79 ? 149 TRP L CD2 1 ATOM 5339 N NE1 . TRP B 2 149 ? -150.095 -197.782 260.059 1.00 86.05 ? 149 TRP L NE1 1 ATOM 5340 C CE2 . TRP B 2 149 ? -150.116 -197.692 261.425 1.00 90.06 ? 149 TRP L CE2 1 ATOM 5341 C CE3 . TRP B 2 149 ? -149.891 -199.177 263.320 1.00 88.73 ? 149 TRP L CE3 1 ATOM 5342 C CZ2 . TRP B 2 149 ? -150.288 -196.578 262.253 1.00 86.04 ? 149 TRP L CZ2 1 ATOM 5343 C CZ3 . TRP B 2 149 ? -150.066 -198.073 264.140 1.00 89.50 ? 149 TRP L CZ3 1 ATOM 5344 C CH2 . TRP B 2 149 ? -150.264 -196.789 263.604 1.00 84.38 ? 149 TRP L CH2 1 ATOM 5345 N N . LYS B 2 150 ? -147.985 -203.549 262.554 1.00 101.23 ? 150 LYS L N 1 ATOM 5346 C CA . LYS B 2 150 ? -148.049 -204.926 263.054 1.00 100.20 ? 150 LYS L CA 1 ATOM 5347 C C . LYS B 2 150 ? -148.948 -205.053 264.285 1.00 98.21 ? 150 LYS L C 1 ATOM 5348 O O . LYS B 2 150 ? -148.743 -204.364 265.282 1.00 104.36 ? 150 LYS L O 1 ATOM 5349 C CB . LYS B 2 150 ? -146.648 -205.440 263.407 1.00 98.45 ? 150 LYS L CB 1 ATOM 5350 C CG . LYS B 2 150 ? -145.809 -205.950 262.247 1.00 92.10 ? 150 LYS L CG 1 ATOM 5351 C CD . LYS B 2 150 ? -144.434 -206.363 262.746 1.00 97.99 ? 150 LYS L CD 1 ATOM 5352 C CE . LYS B 2 150 ? -143.469 -206.664 261.617 1.00 102.20 ? 150 LYS L CE 1 ATOM 5353 N NZ . LYS B 2 150 ? -142.054 -206.521 262.087 1.00 105.60 ? 150 LYS L NZ 1 ATOM 5354 N N . ILE B 2 151 ? -149.951 -205.921 264.206 1.00 99.95 ? 151 ILE L N 1 ATOM 5355 C CA . ILE B 2 151 ? -150.643 -206.401 265.401 1.00 107.35 ? 151 ILE L CA 1 ATOM 5356 C C . ILE B 2 151 ? -150.019 -207.756 265.771 1.00 113.16 ? 151 ILE L C 1 ATOM 5357 O O . ILE B 2 151 ? -149.823 -208.608 264.900 1.00 112.81 ? 151 ILE L O 1 ATOM 5358 C CB . ILE B 2 151 ? -152.167 -206.519 265.185 1.00 107.81 ? 151 ILE L CB 1 ATOM 5359 C CG1 . ILE B 2 151 ? -152.491 -207.566 264.107 1.00 120.11 ? 151 ILE L CG1 1 ATOM 5360 C CG2 . ILE B 2 151 ? -152.743 -205.168 264.780 1.00 99.26 ? 151 ILE L CG2 1 ATOM 5361 C CD1 . ILE B 2 151 ? -152.673 -209.004 264.610 1.00 111.96 ? 151 ILE L CD1 1 ATOM 5362 N N . GLU B 2 152 ? -149.707 -207.952 267.053 1.00 116.66 ? 152 GLU L N 1 ATOM 5363 C CA . GLU B 2 152 ? -148.816 -209.026 267.480 1.00 115.58 ? 152 GLU L CA 1 ATOM 5364 C C . GLU B 2 152 ? -147.508 -208.733 266.795 1.00 114.57 ? 152 GLU L C 1 ATOM 5365 O O . GLU B 2 152 ? -147.006 -207.602 266.832 1.00 114.56 ? 152 GLU L O 1 ATOM 5366 C CB . GLU B 2 152 ? -149.303 -210.427 267.077 1.00 117.78 ? 152 GLU L CB 1 ATOM 5367 C CG . GLU B 2 152 ? -150.606 -210.907 267.709 1.00 130.99 ? 152 GLU L CG 1 ATOM 5368 C CD . GLU B 2 152 ? -150.497 -211.145 269.214 1.00 141.83 ? 152 GLU L CD 1 ATOM 5369 O OE1 . GLU B 2 152 ? -149.423 -210.868 269.794 1.00 145.99 ? 152 GLU L OE1 1 ATOM 5370 O OE2 . GLU B 2 152 ? -151.505 -211.572 269.824 1.00 142.97 ? 152 GLU L OE2 1 ATOM 5371 N N . GLY B 2 153 ? -146.964 -209.769 266.166 1.00 109.89 ? 153 GLY L N 1 ATOM 5372 C CA . GLY B 2 153 ? -145.886 -209.609 265.215 1.00 108.33 ? 153 GLY L CA 1 ATOM 5373 C C . GLY B 2 153 ? -146.379 -209.667 263.780 1.00 110.76 ? 153 GLY L C 1 ATOM 5374 O O . GLY B 2 153 ? -145.622 -209.368 262.854 1.00 114.71 ? 153 GLY L O 1 ATOM 5375 N N . SER B 2 154 ? -147.633 -210.069 263.580 1.00 110.20 ? 154 SER L N 1 ATOM 5376 C CA . SER B 2 154 ? -148.200 -210.092 262.231 1.00 106.29 ? 154 SER L CA 1 ATOM 5377 C C . SER B 2 154 ? -148.351 -208.686 261.656 1.00 106.97 ? 154 SER L C 1 ATOM 5378 O O . SER B 2 154 ? -148.851 -207.780 262.327 1.00 109.41 ? 154 SER L O 1 ATOM 5379 C CB . SER B 2 154 ? -149.560 -210.792 262.229 1.00 100.34 ? 154 SER L CB 1 ATOM 5380 O OG . SER B 2 154 ? -149.394 -212.182 262.424 1.00 111.19 ? 154 SER L OG 1 ATOM 5381 N N . GLU B 2 155 ? -147.943 -208.500 260.405 1.00 101.85 ? 155 GLU L N 1 ATOM 5382 C CA . GLU B 2 155 ? -148.170 -207.213 259.763 1.00 100.76 ? 155 GLU L CA 1 ATOM 5383 C C . GLU B 2 155 ? -149.617 -207.106 259.281 1.00 98.10 ? 155 GLU L C 1 ATOM 5384 O O . GLU B 2 155 ? -150.235 -208.101 258.906 1.00 90.89 ? 155 GLU L O 1 ATOM 5385 C CB . GLU B 2 155 ? -147.186 -206.993 258.609 1.00 98.94 ? 155 GLU L CB 1 ATOM 5386 C CG . GLU B 2 155 ? -147.219 -208.046 257.520 1.00 103.87 ? 155 GLU L CG 1 ATOM 5387 C CD . GLU B 2 155 ? -146.340 -207.678 256.326 1.00 113.55 ? 155 GLU L CD 1 ATOM 5388 O OE1 . GLU B 2 155 ? -145.932 -206.496 256.224 1.00 113.32 ? 155 GLU L OE1 1 ATOM 5389 O OE2 . GLU B 2 155 ? -146.059 -208.571 255.490 1.00 115.49 ? 155 GLU L OE2 1 ATOM 5390 N N . ARG B 2 156 ? -150.160 -205.894 259.295 1.00 97.38 ? 156 ARG L N 1 ATOM 5391 C CA . ARG B 2 156 ? -151.477 -205.664 258.719 1.00 94.81 ? 156 ARG L CA 1 ATOM 5392 C C . ARG B 2 156 ? -151.365 -204.642 257.595 1.00 95.18 ? 156 ARG L C 1 ATOM 5393 O O . ARG B 2 156 ? -150.848 -203.544 257.810 1.00 97.74 ? 156 ARG L O 1 ATOM 5394 C CB . ARG B 2 156 ? -152.459 -205.182 259.778 1.00 95.75 ? 156 ARG L CB 1 ATOM 5395 C CG . ARG B 2 156 ? -153.874 -205.058 259.252 1.00 99.15 ? 156 ARG L CG 1 ATOM 5396 C CD . ARG B 2 156 ? -154.823 -204.569 260.324 1.00 112.06 ? 156 ARG L CD 1 ATOM 5397 N NE . ARG B 2 156 ? -156.170 -204.364 259.799 1.00 117.43 ? 156 ARG L NE 1 ATOM 5398 C CZ . ARG B 2 156 ? -157.073 -205.330 259.686 1.00 124.39 ? 156 ARG L CZ 1 ATOM 5399 N NH1 . ARG B 2 156 ? -156.764 -206.570 260.059 1.00 119.19 ? 156 ARG L NH1 1 ATOM 5400 N NH2 . ARG B 2 156 ? -158.278 -205.053 259.196 1.00 129.72 ? 156 ARG L NH2 1 ATOM 5401 N N . GLN B 2 157 ? -151.820 -205.004 256.397 1.00 85.06 ? 157 GLN L N 1 ATOM 5402 C CA . GLN B 2 157 ? -151.659 -204.130 255.235 1.00 82.95 ? 157 GLN L CA 1 ATOM 5403 C C . GLN B 2 157 ? -152.916 -203.328 254.895 1.00 83.68 ? 157 GLN L C 1 ATOM 5404 O O . GLN B 2 157 ? -152.832 -202.204 254.397 1.00 80.58 ? 157 GLN L O 1 ATOM 5405 C CB . GLN B 2 157 ? -151.227 -204.959 254.028 1.00 83.40 ? 157 GLN L CB 1 ATOM 5406 C CG . GLN B 2 157 ? -149.907 -205.685 254.251 1.00 92.31 ? 157 GLN L CG 1 ATOM 5407 C CD . GLN B 2 157 ? -149.673 -206.803 253.263 1.00 91.77 ? 157 GLN L CD 1 ATOM 5408 O OE1 . GLN B 2 157 ? -150.605 -207.294 252.620 1.00 90.47 ? 157 GLN L OE1 1 ATOM 5409 N NE2 . GLN B 2 157 ? -148.418 -207.217 253.135 1.00 98.43 ? 157 GLN L NE2 1 ATOM 5410 N N . ASN B 2 158 ? -154.075 -203.920 255.165 1.00 89.47 ? 158 ASN L N 1 ATOM 5411 C CA . ASN B 2 158 ? -155.366 -203.317 254.866 1.00 83.07 ? 158 ASN L CA 1 ATOM 5412 C C . ASN B 2 158 ? -155.764 -202.193 255.832 1.00 83.27 ? 158 ASN L C 1 ATOM 5413 O O . ASN B 2 158 ? -155.299 -202.159 256.970 1.00 86.49 ? 158 ASN L O 1 ATOM 5414 C CB . ASN B 2 158 ? -156.438 -204.412 254.860 1.00 88.30 ? 158 ASN L CB 1 ATOM 5415 C CG . ASN B 2 158 ? -157.723 -203.957 254.197 1.00 106.24 ? 158 ASN L CG 1 ATOM 5416 O OD1 . ASN B 2 158 ? -157.695 -203.145 253.254 1.00 105.02 ? 158 ASN L OD1 1 ATOM 5417 N ND2 . ASN B 2 158 ? -158.861 -204.463 254.686 1.00 110.68 ? 158 ASN L ND2 1 ATOM 5418 N N . GLY B 2 159 ? -156.629 -201.280 255.380 1.00 81.91 ? 159 GLY L N 1 ATOM 5419 C CA . GLY B 2 159 ? -157.239 -200.296 256.267 1.00 78.33 ? 159 GLY L CA 1 ATOM 5420 C C . GLY B 2 159 ? -156.378 -199.161 256.798 1.00 79.05 ? 159 GLY L C 1 ATOM 5421 O O . GLY B 2 159 ? -156.514 -198.754 257.953 1.00 79.41 ? 159 GLY L O 1 ATOM 5422 N N . VAL B 2 160 ? -155.478 -198.657 255.963 1.00 77.62 ? 160 VAL L N 1 ATOM 5423 C CA . VAL B 2 160 ? -154.559 -197.605 256.369 1.00 72.58 ? 160 VAL L CA 1 ATOM 5424 C C . VAL B 2 160 ? -154.744 -196.297 255.592 1.00 76.45 ? 160 VAL L C 1 ATOM 5425 O O . VAL B 2 160 ? -155.214 -196.286 254.455 1.00 75.02 ? 160 VAL L O 1 ATOM 5426 C CB . VAL B 2 160 ? -153.109 -198.089 256.213 1.00 72.13 ? 160 VAL L CB 1 ATOM 5427 C CG1 . VAL B 2 160 ? -152.115 -196.954 256.435 1.00 69.57 ? 160 VAL L CG1 1 ATOM 5428 C CG2 . VAL B 2 160 ? -152.852 -199.234 257.171 1.00 75.80 ? 160 VAL L CG2 1 ATOM 5429 N N . LEU B 2 161 ? -154.385 -195.190 256.233 1.00 78.94 ? 161 LEU L N 1 ATOM 5430 C CA . LEU B 2 161 ? -154.382 -193.892 255.580 1.00 76.55 ? 161 LEU L CA 1 ATOM 5431 C C . LEU B 2 161 ? -153.053 -193.187 255.836 1.00 74.90 ? 161 LEU L C 1 ATOM 5432 O O . LEU B 2 161 ? -152.623 -193.053 256.972 1.00 78.20 ? 161 LEU L O 1 ATOM 5433 C CB . LEU B 2 161 ? -155.555 -193.035 256.071 1.00 75.40 ? 161 LEU L CB 1 ATOM 5434 C CG . LEU B 2 161 ? -155.699 -191.647 255.433 1.00 79.68 ? 161 LEU L CG 1 ATOM 5435 C CD1 . LEU B 2 161 ? -157.103 -191.108 255.613 1.00 71.55 ? 161 LEU L CD1 1 ATOM 5436 C CD2 . LEU B 2 161 ? -154.674 -190.661 255.985 1.00 77.10 ? 161 LEU L CD2 1 ATOM 5437 N N . ASN B 2 162 ? -152.414 -192.724 254.774 1.00 75.43 ? 162 ASN L N 1 ATOM 5438 C CA . ASN B 2 162 ? -151.125 -192.073 254.907 1.00 72.90 ? 162 ASN L CA 1 ATOM 5439 C C . ASN B 2 162 ? -151.193 -190.667 254.372 1.00 72.22 ? 162 ASN L C 1 ATOM 5440 O O . ASN B 2 162 ? -151.705 -190.447 253.285 1.00 73.56 ? 162 ASN L O 1 ATOM 5441 C CB . ASN B 2 162 ? -150.040 -192.840 254.155 1.00 76.37 ? 162 ASN L CB 1 ATOM 5442 C CG . ASN B 2 162 ? -149.916 -194.276 254.605 1.00 78.60 ? 162 ASN L CG 1 ATOM 5443 O OD1 . ASN B 2 162 ? -149.931 -194.562 255.802 1.00 77.08 ? 162 ASN L OD1 1 ATOM 5444 N ND2 . ASN B 2 162 ? -149.782 -195.195 253.637 1.00 74.91 ? 162 ASN L ND2 1 ATOM 5445 N N . SER B 2 163 ? -150.665 -189.717 255.130 1.00 75.69 ? 163 SER L N 1 ATOM 5446 C CA . SER B 2 163 ? -150.613 -188.334 254.688 1.00 75.01 ? 163 SER L CA 1 ATOM 5447 C C . SER B 2 163 ? -149.182 -187.839 254.725 1.00 73.39 ? 163 SER L C 1 ATOM 5448 O O . SER B 2 163 ? -148.445 -188.190 255.627 1.00 74.41 ? 163 SER L O 1 ATOM 5449 C CB . SER B 2 163 ? -151.510 -187.460 255.567 1.00 76.69 ? 163 SER L CB 1 ATOM 5450 O OG . SER B 2 163 ? -151.621 -186.142 255.052 1.00 75.38 ? 163 SER L OG 1 ATOM 5451 N N . TRP B 2 164 ? -148.795 -187.042 253.733 1.00 75.72 ? 164 TRP L N 1 ATOM 5452 C CA . TRP B 2 164 ? -147.458 -186.455 253.680 1.00 75.95 ? 164 TRP L CA 1 ATOM 5453 C C . TRP B 2 164 ? -147.596 -184.937 253.691 1.00 73.71 ? 164 TRP L C 1 ATOM 5454 O O . TRP B 2 164 ? -148.452 -184.391 253.004 1.00 73.45 ? 164 TRP L O 1 ATOM 5455 C CB . TRP B 2 164 ? -146.681 -186.897 252.423 1.00 78.49 ? 164 TRP L CB 1 ATOM 5456 C CG . TRP B 2 164 ? -146.412 -188.373 252.270 1.00 83.21 ? 164 TRP L CG 1 ATOM 5457 C CD1 . TRP B 2 164 ? -146.353 -189.316 253.262 1.00 90.27 ? 164 TRP L CD1 1 ATOM 5458 C CD2 . TRP B 2 164 ? -146.182 -189.072 251.042 1.00 88.89 ? 164 TRP L CD2 1 ATOM 5459 N NE1 . TRP B 2 164 ? -146.090 -190.565 252.725 1.00 84.40 ? 164 TRP L NE1 1 ATOM 5460 C CE2 . TRP B 2 164 ? -145.985 -190.440 251.366 1.00 90.26 ? 164 TRP L CE2 1 ATOM 5461 C CE3 . TRP B 2 164 ? -146.120 -188.675 249.691 1.00 90.63 ? 164 TRP L CE3 1 ATOM 5462 C CZ2 . TRP B 2 164 ? -145.725 -191.404 250.396 1.00 95.95 ? 164 TRP L CZ2 1 ATOM 5463 C CZ3 . TRP B 2 164 ? -145.854 -189.632 248.726 1.00 86.18 ? 164 TRP L CZ3 1 ATOM 5464 C CH2 . TRP B 2 164 ? -145.662 -190.983 249.082 1.00 98.54 ? 164 TRP L CH2 1 ATOM 5465 N N . THR B 2 165 ? -146.773 -184.264 254.488 1.00 75.37 ? 165 THR L N 1 ATOM 5466 C CA . THR B 2 165 ? -146.705 -182.808 254.464 1.00 73.15 ? 165 THR L CA 1 ATOM 5467 C C . THR B 2 165 ? -145.901 -182.348 253.270 1.00 77.10 ? 165 THR L C 1 ATOM 5468 O O . THR B 2 165 ? -145.096 -183.105 252.735 1.00 79.50 ? 165 THR L O 1 ATOM 5469 C CB . THR B 2 165 ? -146.072 -182.226 255.721 1.00 70.47 ? 165 THR L CB 1 ATOM 5470 O OG1 . THR B 2 165 ? -144.756 -182.763 255.877 1.00 75.88 ? 165 THR L OG1 1 ATOM 5471 C CG2 . THR B 2 165 ? -146.916 -182.542 256.972 1.00 70.56 ? 165 THR L CG2 1 ATOM 5472 N N . ASP B 2 166 ? -146.142 -181.117 252.838 1.00 78.75 ? 166 ASP L N 1 ATOM 5473 C CA . ASP B 2 166 ? -145.264 -180.477 251.872 1.00 81.75 ? 166 ASP L CA 1 ATOM 5474 C C . ASP B 2 166 ? -143.936 -180.182 252.561 1.00 82.93 ? 166 ASP L C 1 ATOM 5475 O O . ASP B 2 166 ? -143.858 -180.149 253.800 1.00 80.48 ? 166 ASP L O 1 ATOM 5476 C CB . ASP B 2 166 ? -145.885 -179.204 251.304 1.00 87.09 ? 166 ASP L CB 1 ATOM 5477 C CG . ASP B 2 166 ? -147.117 -179.485 250.464 1.00 97.48 ? 166 ASP L CG 1 ATOM 5478 O OD1 . ASP B 2 166 ? -147.391 -180.678 250.204 1.00 96.36 ? 166 ASP L OD1 1 ATOM 5479 O OD2 . ASP B 2 166 ? -147.807 -178.521 250.053 1.00 100.66 ? 166 ASP L OD2 1 ATOM 5480 N N . GLN B 2 167 ? -142.880 -180.040 251.766 1.00 82.35 ? 167 GLN L N 1 ATOM 5481 C CA . GLN B 2 167 ? -141.558 -179.778 252.311 1.00 79.55 ? 167 GLN L CA 1 ATOM 5482 C C . GLN B 2 167 ? -141.545 -178.476 253.118 1.00 84.52 ? 167 GLN L C 1 ATOM 5483 O O . GLN B 2 167 ? -142.068 -177.439 252.691 1.00 81.43 ? 167 GLN L O 1 ATOM 5484 C CB . GLN B 2 167 ? -140.524 -179.724 251.185 1.00 72.10 ? 167 GLN L CB 1 ATOM 5485 C CG . GLN B 2 167 ? -139.105 -179.670 251.679 1.00 77.51 ? 167 GLN L CG 1 ATOM 5486 C CD . GLN B 2 167 ? -138.095 -179.641 250.551 1.00 81.39 ? 167 GLN L CD 1 ATOM 5487 O OE1 . GLN B 2 167 ? -138.340 -179.060 249.481 1.00 80.21 ? 167 GLN L OE1 1 ATOM 5488 N NE2 . GLN B 2 167 ? -136.948 -180.272 250.779 1.00 79.38 ? 167 GLN L NE2 1 ATOM 5489 N N . ASP B 2 168 ? -140.939 -178.551 254.295 1.00 86.88 ? 168 ASP L N 1 ATOM 5490 C CA . ASP B 2 168 ? -140.872 -177.429 255.213 1.00 88.13 ? 168 ASP L CA 1 ATOM 5491 C C . ASP B 2 168 ? -140.075 -176.276 254.596 1.00 89.77 ? 168 ASP L C 1 ATOM 5492 O O . ASP B 2 168 ? -138.979 -176.481 254.080 1.00 90.46 ? 168 ASP L O 1 ATOM 5493 C CB . ASP B 2 168 ? -140.241 -177.908 256.530 1.00 92.12 ? 168 ASP L CB 1 ATOM 5494 C CG . ASP B 2 168 ? -140.387 -176.914 257.660 1.00 98.03 ? 168 ASP L CG 1 ATOM 5495 O OD1 . ASP B 2 168 ? -140.147 -175.707 257.434 1.00 98.21 ? 168 ASP L OD1 1 ATOM 5496 O OD2 . ASP B 2 168 ? -140.729 -177.354 258.784 1.00 101.61 ? 168 ASP L OD2 1 ATOM 5497 N N . SER B 2 169 ? -140.610 -175.062 254.684 1.00 91.11 ? 169 SER L N 1 ATOM 5498 C CA . SER B 2 169 ? -139.898 -173.884 254.201 1.00 88.80 ? 169 SER L CA 1 ATOM 5499 C C . SER B 2 169 ? -138.743 -173.529 255.138 1.00 92.10 ? 169 SER L C 1 ATOM 5500 O O . SER B 2 169 ? -137.824 -172.814 254.747 1.00 91.82 ? 169 SER L O 1 ATOM 5501 C CB . SER B 2 169 ? -140.854 -172.695 254.059 1.00 87.96 ? 169 SER L CB 1 ATOM 5502 N N . LYS B 2 170 ? -138.800 -174.030 256.372 1.00 94.06 ? 170 LYS L N 1 ATOM 5503 C CA . LYS B 2 170 ? -137.772 -173.754 257.377 1.00 93.82 ? 170 LYS L CA 1 ATOM 5504 C C . LYS B 2 170 ? -136.597 -174.734 257.263 1.00 93.32 ? 170 LYS L C 1 ATOM 5505 O O . LYS B 2 170 ? -135.552 -174.374 256.723 1.00 85.90 ? 170 LYS L O 1 ATOM 5506 C CB . LYS B 2 170 ? -138.368 -173.802 258.791 1.00 97.91 ? 170 LYS L CB 1 ATOM 5507 N N . ASP B 2 171 ? -136.763 -175.961 257.770 1.00 94.91 ? 171 ASP L N 1 ATOM 5508 C CA . ASP B 2 171 ? -135.683 -176.955 257.720 1.00 91.48 ? 171 ASP L CA 1 ATOM 5509 C C . ASP B 2 171 ? -135.696 -177.840 256.461 1.00 92.89 ? 171 ASP L C 1 ATOM 5510 O O . ASP B 2 171 ? -134.829 -178.698 256.297 1.00 92.10 ? 171 ASP L O 1 ATOM 5511 C CB . ASP B 2 171 ? -135.698 -177.843 258.981 1.00 88.39 ? 171 ASP L CB 1 ATOM 5512 C CG . ASP B 2 171 ? -136.962 -178.688 259.117 1.00 94.42 ? 171 ASP L CG 1 ATOM 5513 O OD1 . ASP B 2 171 ? -137.712 -178.839 258.127 1.00 94.42 ? 171 ASP L OD1 1 ATOM 5514 O OD2 . ASP B 2 171 ? -137.195 -179.224 260.228 1.00 93.27 ? 171 ASP L OD2 1 ATOM 5515 N N . SER B 2 172 ? -136.677 -177.639 255.584 1.00 91.12 ? 172 SER L N 1 ATOM 5516 C CA . SER B 2 172 ? -136.764 -178.394 254.332 1.00 88.48 ? 172 SER L CA 1 ATOM 5517 C C . SER B 2 172 ? -136.925 -179.905 254.512 1.00 88.01 ? 172 SER L C 1 ATOM 5518 O O . SER B 2 172 ? -136.542 -180.672 253.627 1.00 86.52 ? 172 SER L O 1 ATOM 5519 C CB . SER B 2 172 ? -135.521 -178.131 253.471 1.00 82.06 ? 172 SER L CB 1 ATOM 5520 O OG . SER B 2 172 ? -135.593 -176.860 252.839 1.00 83.76 ? 172 SER L OG 1 ATOM 5521 N N . THR B 2 173 ? -137.498 -180.334 255.635 1.00 83.91 ? 173 THR L N 1 ATOM 5522 C CA . THR B 2 173 ? -137.757 -181.760 255.851 1.00 83.13 ? 173 THR L CA 1 ATOM 5523 C C . THR B 2 173 ? -139.200 -182.154 255.545 1.00 84.02 ? 173 THR L C 1 ATOM 5524 O O . THR B 2 173 ? -140.068 -181.295 255.342 1.00 83.22 ? 173 THR L O 1 ATOM 5525 C CB . THR B 2 173 ? -137.442 -182.184 257.294 1.00 85.96 ? 173 THR L CB 1 ATOM 5526 O OG1 . THR B 2 173 ? -138.439 -181.663 258.182 1.00 83.98 ? 173 THR L OG1 1 ATOM 5527 C CG2 . THR B 2 173 ? -136.077 -181.673 257.703 1.00 87.81 ? 173 THR L CG2 1 ATOM 5528 N N . TYR B 2 174 ? -139.438 -183.463 255.492 1.00 78.88 ? 174 TYR L N 1 ATOM 5529 C CA . TYR B 2 174 ? -140.775 -184.006 255.243 1.00 76.29 ? 174 TYR L CA 1 ATOM 5530 C C . TYR B 2 174 ? -141.358 -184.679 256.483 1.00 77.89 ? 174 TYR L C 1 ATOM 5531 O O . TYR B 2 174 ? -140.614 -185.136 257.349 1.00 84.48 ? 174 TYR L O 1 ATOM 5532 C CB . TYR B 2 174 ? -140.733 -185.001 254.083 1.00 79.04 ? 174 TYR L CB 1 ATOM 5533 C CG . TYR B 2 174 ? -140.372 -184.367 252.761 1.00 75.96 ? 174 TYR L CG 1 ATOM 5534 C CD1 . TYR B 2 174 ? -141.347 -183.836 251.932 1.00 69.51 ? 174 TYR L CD1 1 ATOM 5535 C CD2 . TYR B 2 174 ? -139.045 -184.287 252.351 1.00 73.28 ? 174 TYR L CD2 1 ATOM 5536 C CE1 . TYR B 2 174 ? -141.006 -183.249 250.724 1.00 71.89 ? 174 TYR L CE1 1 ATOM 5537 C CE2 . TYR B 2 174 ? -138.701 -183.702 251.154 1.00 71.53 ? 174 TYR L CE2 1 ATOM 5538 C CZ . TYR B 2 174 ? -139.683 -183.188 250.347 1.00 69.99 ? 174 TYR L CZ 1 ATOM 5539 O OH . TYR B 2 174 ? -139.339 -182.602 249.157 1.00 74.09 ? 174 TYR L OH 1 ATOM 5540 N N . SER B 2 175 ? -142.684 -184.744 256.573 1.00 71.36 ? 175 SER L N 1 ATOM 5541 C CA . SER B 2 175 ? -143.323 -185.472 257.657 1.00 75.91 ? 175 SER L CA 1 ATOM 5542 C C . SER B 2 175 ? -144.523 -186.253 257.153 1.00 78.16 ? 175 SER L C 1 ATOM 5543 O O . SER B 2 175 ? -145.131 -185.899 256.149 1.00 77.44 ? 175 SER L O 1 ATOM 5544 C CB . SER B 2 175 ? -143.748 -184.522 258.764 1.00 77.84 ? 175 SER L CB 1 ATOM 5545 O OG . SER B 2 175 ? -142.630 -183.816 259.260 1.00 85.80 ? 175 SER L OG 1 ATOM 5546 N N . MET B 2 176 ? -144.862 -187.322 257.861 1.00 76.50 ? 176 MET L N 1 ATOM 5547 C CA . MET B 2 176 ? -145.949 -188.182 257.440 1.00 76.94 ? 176 MET L CA 1 ATOM 5548 C C . MET B 2 176 ? -146.781 -188.711 258.599 1.00 75.15 ? 176 MET L C 1 ATOM 5549 O O . MET B 2 176 ? -146.272 -188.948 259.684 1.00 77.99 ? 176 MET L O 1 ATOM 5550 C CB . MET B 2 176 ? -145.416 -189.367 256.629 1.00 78.19 ? 176 MET L CB 1 ATOM 5551 C CG . MET B 2 176 ? -146.343 -190.577 256.700 1.00 73.95 ? 176 MET L CG 1 ATOM 5552 S SD . MET B 2 176 ? -145.733 -191.995 255.794 1.00 86.14 ? 176 MET L SD 1 ATOM 5553 C CE . MET B 2 176 ? -147.097 -193.147 255.984 1.00 73.09 ? 176 MET L CE 1 ATOM 5554 N N . SER B 2 177 ? -148.068 -188.920 258.334 1.00 76.97 ? 177 SER L N 1 ATOM 5555 C CA . SER B 2 177 ? -148.990 -189.472 259.315 1.00 78.35 ? 177 SER L CA 1 ATOM 5556 C C . SER B 2 177 ? -149.640 -190.741 258.766 1.00 78.33 ? 177 SER L C 1 ATOM 5557 O O . SER B 2 177 ? -150.180 -190.742 257.665 1.00 78.72 ? 177 SER L O 1 ATOM 5558 C CB . SER B 2 177 ? -150.045 -188.425 259.685 1.00 74.81 ? 177 SER L CB 1 ATOM 5559 O OG . SER B 2 177 ? -151.100 -188.981 260.435 1.00 80.98 ? 177 SER L OG 1 ATOM 5560 N N . SER B 2 178 ? -149.577 -191.827 259.524 1.00 76.78 ? 178 SER L N 1 ATOM 5561 C CA . SER B 2 178 ? -150.236 -193.060 259.112 1.00 77.65 ? 178 SER L CA 1 ATOM 5562 C C . SER B 2 178 ? -151.289 -193.472 260.128 1.00 80.63 ? 178 SER L C 1 ATOM 5563 O O . SER B 2 178 ? -150.990 -193.629 261.304 1.00 80.36 ? 178 SER L O 1 ATOM 5564 C CB . SER B 2 178 ? -149.228 -194.189 258.938 1.00 76.37 ? 178 SER L CB 1 ATOM 5565 O OG . SER B 2 178 ? -149.903 -195.423 258.798 1.00 74.18 ? 178 SER L OG 1 ATOM 5566 N N . THR B 2 179 ? -152.519 -193.667 259.673 1.00 80.77 ? 179 THR L N 1 ATOM 5567 C CA . THR B 2 179 ? -153.592 -194.019 260.582 1.00 77.52 ? 179 THR L CA 1 ATOM 5568 C C . THR B 2 179 ? -154.193 -195.373 260.235 1.00 80.85 ? 179 THR L C 1 ATOM 5569 O O . THR B 2 179 ? -154.742 -195.561 259.148 1.00 81.70 ? 179 THR L O 1 ATOM 5570 C CB . THR B 2 179 ? -154.695 -192.967 260.572 1.00 78.94 ? 179 THR L CB 1 ATOM 5571 O OG1 . THR B 2 179 ? -154.128 -191.679 260.846 1.00 83.95 ? 179 THR L OG1 1 ATOM 5572 C CG2 . THR B 2 179 ? -155.734 -193.292 261.618 1.00 79.27 ? 179 THR L CG2 1 ATOM 5573 N N . LEU B 2 180 ? -154.071 -196.309 261.175 1.00 83.37 ? 180 LEU L N 1 ATOM 5574 C CA . LEU B 2 180 ? -154.651 -197.644 261.077 1.00 80.14 ? 180 LEU L CA 1 ATOM 5575 C C . LEU B 2 180 ? -155.967 -197.691 261.838 1.00 81.58 ? 180 LEU L C 1 ATOM 5576 O O . LEU B 2 180 ? -155.981 -197.516 263.053 1.00 84.90 ? 180 LEU L O 1 ATOM 5577 C CB . LEU B 2 180 ? -153.679 -198.676 261.635 1.00 83.04 ? 180 LEU L CB 1 ATOM 5578 C CG . LEU B 2 180 ? -154.206 -200.090 261.822 1.00 86.30 ? 180 LEU L CG 1 ATOM 5579 C CD1 . LEU B 2 180 ? -154.583 -200.705 260.477 1.00 84.38 ? 180 LEU L CD1 1 ATOM 5580 C CD2 . LEU B 2 180 ? -153.136 -200.897 262.509 1.00 86.80 ? 180 LEU L CD2 1 ATOM 5581 N N . THR B 2 181 ? -157.079 -197.892 261.138 1.00 82.60 ? 181 THR L N 1 ATOM 5582 C CA . THR B 2 181 ? -158.371 -197.888 261.822 1.00 88.54 ? 181 THR L CA 1 ATOM 5583 C C . THR B 2 181 ? -158.969 -199.295 261.877 1.00 89.74 ? 181 THR L C 1 ATOM 5584 O O . THR B 2 181 ? -158.939 -200.041 260.896 1.00 83.92 ? 181 THR L O 1 ATOM 5585 C CB . THR B 2 181 ? -159.392 -196.909 261.164 1.00 88.12 ? 181 THR L CB 1 ATOM 5586 O OG1 . THR B 2 181 ? -159.896 -197.475 259.951 1.00 92.79 ? 181 THR L OG1 1 ATOM 5587 C CG2 . THR B 2 181 ? -158.757 -195.535 260.885 1.00 85.56 ? 181 THR L CG2 1 ATOM 5588 N N . LEU B 2 182 ? -159.517 -199.630 263.043 1.00 94.76 ? 182 LEU L N 1 ATOM 5589 C CA . LEU B 2 182 ? -160.132 -200.925 263.303 1.00 87.34 ? 182 LEU L CA 1 ATOM 5590 C C . LEU B 2 182 ? -161.470 -200.724 263.999 1.00 90.92 ? 182 LEU L C 1 ATOM 5591 O O . LEU B 2 182 ? -161.735 -199.663 264.564 1.00 91.19 ? 182 LEU L O 1 ATOM 5592 C CB . LEU B 2 182 ? -159.227 -201.787 264.182 1.00 90.96 ? 182 LEU L CB 1 ATOM 5593 C CG . LEU B 2 182 ? -157.760 -201.924 263.791 1.00 91.32 ? 182 LEU L CG 1 ATOM 5594 C CD1 . LEU B 2 182 ? -156.949 -202.322 265.003 1.00 89.68 ? 182 LEU L CD1 1 ATOM 5595 C CD2 . LEU B 2 182 ? -157.608 -202.950 262.681 1.00 96.52 ? 182 LEU L CD2 1 ATOM 5596 N N . THR B 2 183 ? -162.318 -201.742 263.955 1.00 99.43 ? 183 THR L N 1 ATOM 5597 C CA . THR B 2 183 ? -163.493 -201.764 264.812 1.00 97.92 ? 183 THR L CA 1 ATOM 5598 C C . THR B 2 183 ? -162.984 -201.871 266.240 1.00 99.91 ? 183 THR L C 1 ATOM 5599 O O . THR B 2 183 ? -161.885 -202.387 266.467 1.00 100.11 ? 183 THR L O 1 ATOM 5600 C CB . THR B 2 183 ? -164.430 -202.933 264.492 1.00 96.51 ? 183 THR L CB 1 ATOM 5601 O OG1 . THR B 2 183 ? -163.666 -204.141 264.357 1.00 98.88 ? 183 THR L OG1 1 ATOM 5602 C CG2 . THR B 2 183 ? -165.181 -202.668 263.204 1.00 87.69 ? 183 THR L CG2 1 ATOM 5603 N N . LYS B 2 184 ? -163.746 -201.367 267.205 1.00 100.88 ? 184 LYS L N 1 ATOM 5604 C CA . LYS B 2 184 ? -163.292 -201.491 268.580 1.00 104.36 ? 184 LYS L CA 1 ATOM 5605 C C . LYS B 2 184 ? -163.161 -202.967 268.951 1.00 102.31 ? 184 LYS L C 1 ATOM 5606 O O . LYS B 2 184 ? -162.252 -203.351 269.684 1.00 100.50 ? 184 LYS L O 1 ATOM 5607 C CB . LYS B 2 184 ? -164.252 -200.786 269.552 1.00 101.48 ? 184 LYS L CB 1 ATOM 5608 C CG . LYS B 2 184 ? -163.761 -200.810 270.996 1.00 103.32 ? 184 LYS L CG 1 ATOM 5609 C CD . LYS B 2 184 ? -164.743 -200.172 271.953 1.00 103.49 ? 184 LYS L CD 1 ATOM 5610 C CE . LYS B 2 184 ? -165.891 -201.107 272.291 1.00 107.86 ? 184 LYS L CE 1 ATOM 5611 N NZ . LYS B 2 184 ? -166.931 -200.399 273.096 1.00 110.74 ? 184 LYS L NZ 1 ATOM 5612 N N . ASP B 2 185 ? -164.045 -203.794 268.406 1.00 102.25 ? 185 ASP L N 1 ATOM 5613 C CA . ASP B 2 185 ? -164.021 -205.213 268.722 1.00 103.14 ? 185 ASP L CA 1 ATOM 5614 C C . ASP B 2 185 ? -162.738 -205.850 268.222 1.00 101.62 ? 185 ASP L C 1 ATOM 5615 O O . ASP B 2 185 ? -162.146 -206.673 268.907 1.00 101.88 ? 185 ASP L O 1 ATOM 5616 C CB . ASP B 2 185 ? -165.241 -205.928 268.129 1.00 101.08 ? 185 ASP L CB 1 ATOM 5617 C CG . ASP B 2 185 ? -166.531 -205.604 268.879 1.00 115.00 ? 185 ASP L CG 1 ATOM 5618 O OD1 . ASP B 2 185 ? -166.454 -205.010 269.985 1.00 110.60 ? 185 ASP L OD1 1 ATOM 5619 O OD2 . ASP B 2 185 ? -167.619 -205.956 268.368 1.00 116.84 ? 185 ASP L OD2 1 ATOM 5620 N N . GLU B 2 186 ? -162.290 -205.456 267.037 1.00 108.88 ? 186 GLU L N 1 ATOM 5621 C CA . GLU B 2 186 ? -161.025 -205.973 266.527 1.00 108.79 ? 186 GLU L CA 1 ATOM 5622 C C . GLU B 2 186 ? -159.838 -205.452 267.331 1.00 103.68 ? 186 GLU L C 1 ATOM 5623 O O . GLU B 2 186 ? -158.853 -206.159 267.528 1.00 102.69 ? 186 GLU L O 1 ATOM 5624 C CB . GLU B 2 186 ? -160.852 -205.615 265.049 1.00 108.63 ? 186 GLU L CB 1 ATOM 5625 C CG . GLU B 2 186 ? -159.656 -206.296 264.391 1.00 110.07 ? 186 GLU L CG 1 ATOM 5626 C CD . GLU B 2 186 ? -159.735 -207.820 264.456 1.00 125.00 ? 186 GLU L CD 1 ATOM 5627 O OE1 . GLU B 2 186 ? -160.824 -208.358 264.776 1.00 125.07 ? 186 GLU L OE1 1 ATOM 5628 O OE2 . GLU B 2 186 ? -158.703 -208.481 264.190 1.00 126.02 ? 186 GLU L OE2 1 ATOM 5629 N N . TYR B 2 187 ? -159.935 -204.209 267.787 1.00 104.26 ? 187 TYR L N 1 ATOM 5630 C CA . TYR B 2 187 ? -158.871 -203.614 268.584 1.00 102.96 ? 187 TYR L CA 1 ATOM 5631 C C . TYR B 2 187 ? -158.714 -204.278 269.945 1.00 106.12 ? 187 TYR L C 1 ATOM 5632 O O . TYR B 2 187 ? -157.604 -204.398 270.463 1.00 105.68 ? 187 TYR L O 1 ATOM 5633 C CB . TYR B 2 187 ? -159.120 -202.118 268.778 1.00 98.66 ? 187 TYR L CB 1 ATOM 5634 C CG . TYR B 2 187 ? -158.087 -201.469 269.663 1.00 97.93 ? 187 TYR L CG 1 ATOM 5635 C CD1 . TYR B 2 187 ? -156.762 -201.378 269.260 1.00 91.25 ? 187 TYR L CD1 1 ATOM 5636 C CD2 . TYR B 2 187 ? -158.433 -200.952 270.906 1.00 98.78 ? 187 TYR L CD2 1 ATOM 5637 C CE1 . TYR B 2 187 ? -155.811 -200.785 270.070 1.00 97.66 ? 187 TYR L CE1 1 ATOM 5638 C CE2 . TYR B 2 187 ? -157.492 -200.355 271.720 1.00 95.98 ? 187 TYR L CE2 1 ATOM 5639 C CZ . TYR B 2 187 ? -156.180 -200.277 271.301 1.00 99.13 ? 187 TYR L CZ 1 ATOM 5640 O OH . TYR B 2 187 ? -155.233 -199.689 272.111 1.00 99.23 ? 187 TYR L OH 1 ATOM 5641 N N . GLU B 2 188 ? -159.836 -204.698 270.522 1.00 110.78 ? 188 GLU L N 1 ATOM 5642 C CA . GLU B 2 188 ? -159.842 -205.284 271.862 1.00 109.27 ? 188 GLU L CA 1 ATOM 5643 C C . GLU B 2 188 ? -159.645 -206.795 271.847 1.00 106.45 ? 188 GLU L C 1 ATOM 5644 O O . GLU B 2 188 ? -159.483 -207.414 272.895 1.00 106.36 ? 188 GLU L O 1 ATOM 5645 C CB . GLU B 2 188 ? -161.144 -204.930 272.587 1.00 103.22 ? 188 GLU L CB 1 ATOM 5646 C CG . GLU B 2 188 ? -161.157 -203.522 273.132 1.00 102.97 ? 188 GLU L CG 1 ATOM 5647 C CD . GLU B 2 188 ? -162.532 -203.088 273.591 1.00 113.09 ? 188 GLU L CD 1 ATOM 5648 O OE1 . GLU B 2 188 ? -163.494 -203.872 273.407 1.00 112.94 ? 188 GLU L OE1 1 ATOM 5649 O OE2 . GLU B 2 188 ? -162.648 -201.960 274.129 1.00 112.21 ? 188 GLU L OE2 1 ATOM 5650 N N . ARG B 2 189 ? -159.643 -207.380 270.654 1.00 105.01 ? 189 ARG L N 1 ATOM 5651 C CA . ARG B 2 189 ? -159.462 -208.817 270.507 1.00 103.48 ? 189 ARG L CA 1 ATOM 5652 C C . ARG B 2 189 ? -157.969 -209.115 270.504 1.00 107.57 ? 189 ARG L C 1 ATOM 5653 O O . ARG B 2 189 ? -157.546 -210.244 270.242 1.00 110.52 ? 189 ARG L O 1 ATOM 5654 C CB . ARG B 2 189 ? -160.122 -209.339 269.225 1.00 95.92 ? 189 ARG L CB 1 ATOM 5655 N N . HIS B 2 190 ? -157.166 -208.090 270.768 1.00 103.88 ? 190 HIS L N 1 ATOM 5656 C CA . HIS B 2 190 ? -155.734 -208.267 270.670 1.00 106.30 ? 190 HIS L CA 1 ATOM 5657 C C . HIS B 2 190 ? -154.890 -207.146 271.347 1.00 107.82 ? 190 HIS L C 1 ATOM 5658 O O . HIS B 2 190 ? -155.380 -206.039 271.550 1.00 113.74 ? 190 HIS L O 1 ATOM 5659 C CB . HIS B 2 190 ? -155.390 -208.417 269.198 1.00 103.45 ? 190 HIS L CB 1 ATOM 5660 C CG . HIS B 2 190 ? -153.932 -208.308 268.930 1.00 120.97 ? 190 HIS L CG 1 ATOM 5661 N ND1 . HIS B 2 190 ? -152.986 -208.924 269.722 1.00 118.31 ? 190 HIS L ND1 1 ATOM 5662 C CD2 . HIS B 2 190 ? -153.254 -207.619 267.986 1.00 125.81 ? 190 HIS L CD2 1 ATOM 5663 C CE1 . HIS B 2 190 ? -151.781 -208.606 269.283 1.00 117.70 ? 190 HIS L CE1 1 ATOM 5664 N NE2 . HIS B 2 190 ? -151.916 -207.832 268.224 1.00 129.28 ? 190 HIS L NE2 1 ATOM 5665 N N . ASN B 2 191 ? -153.632 -207.448 271.694 1.00 100.27 ? 191 ASN L N 1 ATOM 5666 C CA . ASN B 2 191 ? -152.840 -206.653 272.640 1.00 108.69 ? 191 ASN L CA 1 ATOM 5667 C C . ASN B 2 191 ? -151.678 -205.786 272.121 1.00 110.34 ? 191 ASN L C 1 ATOM 5668 O O . ASN B 2 191 ? -151.554 -204.617 272.507 1.00 104.70 ? 191 ASN L O 1 ATOM 5669 C CB . ASN B 2 191 ? -152.269 -207.587 273.710 1.00 109.45 ? 191 ASN L CB 1 ATOM 5670 C CG . ASN B 2 191 ? -151.364 -206.856 274.700 1.00 114.16 ? 191 ASN L CG 1 ATOM 5671 O OD1 . ASN B 2 191 ? -151.802 -205.937 275.405 1.00 115.82 ? 191 ASN L OD1 1 ATOM 5672 N ND2 . ASN B 2 191 ? -150.100 -207.267 274.764 1.00 108.79 ? 191 ASN L ND2 1 ATOM 5673 N N . SER B 2 192 ? -150.794 -206.351 271.307 1.00 109.13 ? 192 SER L N 1 ATOM 5674 C CA . SER B 2 192 ? -149.631 -205.588 270.849 1.00 107.79 ? 192 SER L CA 1 ATOM 5675 C C . SER B 2 192 ? -149.856 -204.848 269.516 1.00 108.45 ? 192 SER L C 1 ATOM 5676 O O . SER B 2 192 ? -150.250 -205.443 268.510 1.00 107.75 ? 192 SER L O 1 ATOM 5677 C CB . SER B 2 192 ? -148.423 -206.509 270.718 1.00 108.77 ? 192 SER L CB 1 ATOM 5678 O OG . SER B 2 192 ? -147.282 -205.785 270.289 1.00 103.40 ? 192 SER L OG 1 ATOM 5679 N N . TYR B 2 193 ? -149.584 -203.548 269.507 1.00 102.17 ? 193 TYR L N 1 ATOM 5680 C CA . TYR B 2 193 ? -149.674 -202.766 268.283 1.00 97.82 ? 193 TYR L CA 1 ATOM 5681 C C . TYR B 2 193 ? -148.359 -202.070 268.010 1.00 96.61 ? 193 TYR L C 1 ATOM 5682 O O . TYR B 2 193 ? -147.823 -201.369 268.865 1.00 98.54 ? 193 TYR L O 1 ATOM 5683 C CB . TYR B 2 193 ? -150.816 -201.751 268.368 1.00 98.54 ? 193 TYR L CB 1 ATOM 5684 C CG . TYR B 2 193 ? -152.156 -202.423 268.435 1.00 99.82 ? 193 TYR L CG 1 ATOM 5685 C CD1 . TYR B 2 193 ? -152.812 -202.835 267.281 1.00 96.58 ? 193 TYR L CD1 1 ATOM 5686 C CD2 . TYR B 2 193 ? -152.751 -202.678 269.654 1.00 100.79 ? 193 TYR L CD2 1 ATOM 5687 C CE1 . TYR B 2 193 ? -154.036 -203.474 267.347 1.00 99.26 ? 193 TYR L CE1 1 ATOM 5688 C CE2 . TYR B 2 193 ? -153.968 -203.313 269.733 1.00 102.70 ? 193 TYR L CE2 1 ATOM 5689 C CZ . TYR B 2 193 ? -154.612 -203.713 268.582 1.00 102.93 ? 193 TYR L CZ 1 ATOM 5690 O OH . TYR B 2 193 ? -155.835 -204.349 268.680 1.00 103.36 ? 193 TYR L OH 1 ATOM 5691 N N . THR B 2 194 ? -147.849 -202.266 266.804 1.00 95.43 ? 194 THR L N 1 ATOM 5692 C CA . THR B 2 194 ? -146.566 -201.700 266.434 1.00 98.00 ? 194 THR L CA 1 ATOM 5693 C C . THR B 2 194 ? -146.644 -200.964 265.109 1.00 100.67 ? 194 THR L C 1 ATOM 5694 O O . THR B 2 194 ? -147.415 -201.331 264.216 1.00 100.03 ? 194 THR L O 1 ATOM 5695 C CB . THR B 2 194 ? -145.481 -202.787 266.332 1.00 100.74 ? 194 THR L CB 1 ATOM 5696 O OG1 . THR B 2 194 ? -145.699 -203.779 267.346 1.00 104.82 ? 194 THR L OG1 1 ATOM 5697 C CG2 . THR B 2 194 ? -144.082 -202.167 266.476 1.00 95.58 ? 194 THR L CG2 1 ATOM 5698 N N . CYS B 2 195 ? -145.834 -199.924 264.985 1.00 95.67 ? 195 CYS L N 1 ATOM 5699 C CA . CYS B 2 195 ? -145.743 -199.192 263.737 1.00 95.35 ? 195 CYS L CA 1 ATOM 5700 C C . CYS B 2 195 ? -144.260 -198.913 263.475 1.00 98.45 ? 195 CYS L C 1 ATOM 5701 O O . CYS B 2 195 ? -143.566 -198.347 264.325 1.00 96.47 ? 195 CYS L O 1 ATOM 5702 C CB . CYS B 2 195 ? -146.572 -197.912 263.808 1.00 91.32 ? 195 CYS L CB 1 ATOM 5703 S SG . CYS B 2 195 ? -145.632 -196.402 263.659 1.00 95.81 ? 195 CYS L SG 1 ATOM 5704 N N . GLU B 2 196 ? -143.747 -199.350 262.329 1.00 93.08 ? 196 GLU L N 1 ATOM 5705 C CA . GLU B 2 196 ? -142.313 -199.237 262.096 1.00 93.05 ? 196 GLU L CA 1 ATOM 5706 C C . GLU B 2 196 ? -141.994 -198.634 260.733 1.00 93.13 ? 196 GLU L C 1 ATOM 5707 O O . GLU B 2 196 ? -142.598 -198.983 259.720 1.00 93.30 ? 196 GLU L O 1 ATOM 5708 C CB . GLU B 2 196 ? -141.645 -200.601 262.239 1.00 93.71 ? 196 GLU L CB 1 ATOM 5709 C CG . GLU B 2 196 ? -142.174 -201.648 261.305 1.00 95.63 ? 196 GLU L CG 1 ATOM 5710 C CD . GLU B 2 196 ? -141.391 -202.944 261.378 1.00 103.94 ? 196 GLU L CD 1 ATOM 5711 O OE1 . GLU B 2 196 ? -140.798 -203.215 262.443 1.00 106.96 ? 196 GLU L OE1 1 ATOM 5712 O OE2 . GLU B 2 196 ? -141.375 -203.691 260.369 1.00 109.25 ? 196 GLU L OE2 1 ATOM 5713 N N . ALA B 2 197 ? -141.027 -197.723 260.722 1.00 91.35 ? 197 ALA L N 1 ATOM 5714 C CA . ALA B 2 197 ? -140.716 -196.948 259.533 1.00 91.67 ? 197 ALA L CA 1 ATOM 5715 C C . ALA B 2 197 ? -139.356 -197.297 258.946 1.00 92.83 ? 197 ALA L C 1 ATOM 5716 O O . ALA B 2 197 ? -138.324 -196.879 259.470 1.00 91.06 ? 197 ALA L O 1 ATOM 5717 C CB . ALA B 2 197 ? -140.776 -195.458 259.856 1.00 90.17 ? 197 ALA L CB 1 ATOM 5718 N N . THR B 2 198 ? -139.346 -198.087 257.876 1.00 88.98 ? 198 THR L N 1 ATOM 5719 C CA . THR B 2 198 ? -138.136 -198.193 257.065 1.00 91.71 ? 198 THR L CA 1 ATOM 5720 C C . THR B 2 198 ? -137.882 -196.871 256.328 1.00 93.74 ? 198 THR L C 1 ATOM 5721 O O . THR B 2 198 ? -138.793 -196.305 255.719 1.00 92.25 ? 198 THR L O 1 ATOM 5722 C CB . THR B 2 198 ? -138.236 -199.341 256.053 1.00 85.26 ? 198 THR L CB 1 ATOM 5723 O OG1 . THR B 2 198 ? -138.365 -200.579 256.761 1.00 96.97 ? 198 THR L OG1 1 ATOM 5724 C CG2 . THR B 2 198 ? -137.002 -199.400 255.179 1.00 80.80 ? 198 THR L CG2 1 ATOM 5725 N N . HIS B 2 199 ? -136.635 -196.417 256.342 1.00 88.94 ? 199 HIS L N 1 ATOM 5726 C CA . HIS B 2 199 ? -136.267 -195.160 255.712 1.00 84.19 ? 199 HIS L CA 1 ATOM 5727 C C . HIS B 2 199 ? -134.795 -195.253 255.338 1.00 87.97 ? 199 HIS L C 1 ATOM 5728 O O . HIS B 2 199 ? -134.063 -196.069 255.902 1.00 90.54 ? 199 HIS L O 1 ATOM 5729 C CB . HIS B 2 199 ? -136.541 -193.976 256.644 1.00 83.83 ? 199 HIS L CB 1 ATOM 5730 C CG . HIS B 2 199 ? -136.139 -192.643 256.077 1.00 87.36 ? 199 HIS L CG 1 ATOM 5731 N ND1 . HIS B 2 199 ? -134.840 -192.186 256.096 1.00 88.18 ? 199 HIS L ND1 1 ATOM 5732 C CD2 . HIS B 2 199 ? -136.867 -191.666 255.484 1.00 87.76 ? 199 HIS L CD2 1 ATOM 5733 C CE1 . HIS B 2 199 ? -134.783 -190.987 255.540 1.00 84.25 ? 199 HIS L CE1 1 ATOM 5734 N NE2 . HIS B 2 199 ? -136.001 -190.644 255.165 1.00 81.78 ? 199 HIS L NE2 1 ATOM 5735 N N . LYS B 2 200 ? -134.366 -194.432 254.385 1.00 84.96 ? 200 LYS L N 1 ATOM 5736 C CA . LYS B 2 200 ? -133.018 -194.535 253.836 1.00 89.33 ? 200 LYS L CA 1 ATOM 5737 C C . LYS B 2 200 ? -131.926 -194.320 254.900 1.00 94.77 ? 200 LYS L C 1 ATOM 5738 O O . LYS B 2 200 ? -130.840 -194.892 254.811 1.00 93.60 ? 200 LYS L O 1 ATOM 5739 C CB . LYS B 2 200 ? -132.855 -193.523 252.696 1.00 85.96 ? 200 LYS L CB 1 ATOM 5740 C CG . LYS B 2 200 ? -131.455 -193.418 252.111 1.00 92.94 ? 200 LYS L CG 1 ATOM 5741 C CD . LYS B 2 200 ? -131.324 -192.181 251.220 1.00 89.44 ? 200 LYS L CD 1 ATOM 5742 C CE . LYS B 2 200 ? -129.930 -192.088 250.604 1.00 95.12 ? 200 LYS L CE 1 ATOM 5743 N NZ . LYS B 2 200 ? -129.729 -190.820 249.835 1.00 101.34 ? 200 LYS L NZ 1 ATOM 5744 N N . THR B 2 201 ? -132.228 -193.525 255.921 1.00 92.38 ? 201 THR L N 1 ATOM 5745 C CA . THR B 2 201 ? -131.242 -193.183 256.938 1.00 91.81 ? 201 THR L CA 1 ATOM 5746 C C . THR B 2 201 ? -130.707 -194.393 257.708 1.00 101.40 ? 201 THR L C 1 ATOM 5747 O O . THR B 2 201 ? -129.595 -194.349 258.242 1.00 102.58 ? 201 THR L O 1 ATOM 5748 C CB . THR B 2 201 ? -131.824 -192.196 257.955 1.00 90.72 ? 201 THR L CB 1 ATOM 5749 O OG1 . THR B 2 201 ? -133.022 -192.746 258.531 1.00 89.39 ? 201 THR L OG1 1 ATOM 5750 C CG2 . THR B 2 201 ? -132.116 -190.854 257.285 1.00 83.99 ? 201 THR L CG2 1 ATOM 5751 N N . SER B 2 202 ? -131.490 -195.468 257.785 1.00 102.33 ? 202 SER L N 1 ATOM 5752 C CA . SER B 2 202 ? -131.052 -196.639 258.544 1.00 102.58 ? 202 SER L CA 1 ATOM 5753 C C . SER B 2 202 ? -131.525 -197.973 257.970 1.00 104.27 ? 202 SER L C 1 ATOM 5754 O O . SER B 2 202 ? -132.680 -198.127 257.565 1.00 104.35 ? 202 SER L O 1 ATOM 5755 C CB . SER B 2 202 ? -131.522 -196.521 259.993 1.00 103.94 ? 202 SER L CB 1 ATOM 5756 O OG . SER B 2 202 ? -131.295 -197.729 260.689 1.00 108.62 ? 202 SER L OG 1 ATOM 5757 N N . THR B 2 203 ? -130.610 -198.935 257.952 1.00 110.80 ? 203 THR L N 1 ATOM 5758 C CA . THR B 2 203 ? -130.903 -200.301 257.533 1.00 109.93 ? 203 THR L CA 1 ATOM 5759 C C . THR B 2 203 ? -131.886 -200.977 258.485 1.00 106.79 ? 203 THR L C 1 ATOM 5760 O O . THR B 2 203 ? -132.728 -201.777 258.066 1.00 102.97 ? 203 THR L O 1 ATOM 5761 C CB . THR B 2 203 ? -129.607 -201.126 257.457 1.00 105.97 ? 203 THR L CB 1 ATOM 5762 O OG1 . THR B 2 203 ? -128.857 -200.935 258.665 1.00 106.99 ? 203 THR L OG1 1 ATOM 5763 C CG2 . THR B 2 203 ? -128.758 -200.667 256.287 1.00 99.96 ? 203 THR L CG2 1 ATOM 5764 N N . SER B 2 204 ? -131.767 -200.645 259.769 1.00 104.24 ? 204 SER L N 1 ATOM 5765 C CA . SER B 2 204 ? -132.729 -201.069 260.780 1.00 108.10 ? 204 SER L CA 1 ATOM 5766 C C . SER B 2 204 ? -133.979 -200.180 260.710 1.00 109.74 ? 204 SER L C 1 ATOM 5767 O O . SER B 2 204 ? -133.880 -198.938 260.714 1.00 106.36 ? 204 SER L O 1 ATOM 5768 C CB . SER B 2 204 ? -132.102 -201.031 262.192 1.00 112.91 ? 204 SER L CB 1 ATOM 5769 O OG . SER B 2 204 ? -131.801 -199.702 262.633 1.00 112.33 ? 204 SER L OG 1 ATOM 5770 N N . PRO B 2 205 ? -135.161 -200.806 260.631 1.00 102.03 ? 205 PRO L N 1 ATOM 5771 C CA . PRO B 2 205 ? -136.386 -200.017 260.741 1.00 96.60 ? 205 PRO L CA 1 ATOM 5772 C C . PRO B 2 205 ? -136.471 -199.339 262.105 1.00 98.59 ? 205 PRO L C 1 ATOM 5773 O O . PRO B 2 205 ? -136.072 -199.940 263.103 1.00 100.33 ? 205 PRO L O 1 ATOM 5774 C CB . PRO B 2 205 ? -137.494 -201.066 260.564 1.00 97.16 ? 205 PRO L CB 1 ATOM 5775 C CG . PRO B 2 205 ? -136.850 -202.357 260.940 1.00 99.44 ? 205 PRO L CG 1 ATOM 5776 C CD . PRO B 2 205 ? -135.429 -202.247 260.500 1.00 101.86 ? 205 PRO L CD 1 ATOM 5777 N N . ILE B 2 206 ? -136.990 -198.111 262.135 1.00 92.31 ? 206 ILE L N 1 ATOM 5778 C CA . ILE B 2 206 ? -137.253 -197.411 263.390 1.00 92.56 ? 206 ILE L CA 1 ATOM 5779 C C . ILE B 2 206 ? -138.618 -197.834 263.930 1.00 95.90 ? 206 ILE L C 1 ATOM 5780 O O . ILE B 2 206 ? -139.635 -197.727 263.237 1.00 94.87 ? 206 ILE L O 1 ATOM 5781 C CB . ILE B 2 206 ? -137.197 -195.874 263.202 1.00 89.35 ? 206 ILE L CB 1 ATOM 5782 C CG1 . ILE B 2 206 ? -135.749 -195.430 262.995 1.00 96.42 ? 206 ILE L CG1 1 ATOM 5783 C CG2 . ILE B 2 206 ? -137.795 -195.160 264.391 1.00 78.89 ? 206 ILE L CG2 1 ATOM 5784 C CD1 . ILE B 2 206 ? -135.583 -194.040 262.413 1.00 101.79 ? 206 ILE L CD1 1 ATOM 5785 N N . VAL B 2 207 ? -138.646 -198.318 265.165 1.00 95.71 ? 207 VAL L N 1 ATOM 5786 C CA . VAL B 2 207 ? -139.857 -198.948 265.674 1.00 94.73 ? 207 VAL L CA 1 ATOM 5787 C C . VAL B 2 207 ? -140.393 -198.332 266.960 1.00 97.06 ? 207 VAL L C 1 ATOM 5788 O O . VAL B 2 207 ? -139.669 -198.166 267.941 1.00 100.40 ? 207 VAL L O 1 ATOM 5789 C CB . VAL B 2 207 ? -139.625 -200.436 265.920 1.00 91.89 ? 207 VAL L CB 1 ATOM 5790 C CG1 . VAL B 2 207 ? -140.911 -201.091 266.388 1.00 91.29 ? 207 VAL L CG1 1 ATOM 5791 C CG2 . VAL B 2 207 ? -139.099 -201.097 264.654 1.00 92.94 ? 207 VAL L CG2 1 ATOM 5792 N N . LYS B 2 208 ? -141.678 -197.997 266.934 1.00 98.32 ? 208 LYS L N 1 ATOM 5793 C CA . LYS B 2 208 ? -142.407 -197.583 268.122 1.00 96.16 ? 208 LYS L CA 1 ATOM 5794 C C . LYS B 2 208 ? -143.581 -198.538 268.295 1.00 94.59 ? 208 LYS L C 1 ATOM 5795 O O . LYS B 2 208 ? -144.119 -199.059 267.319 1.00 96.38 ? 208 LYS L O 1 ATOM 5796 C CB . LYS B 2 208 ? -142.880 -196.130 268.014 1.00 92.10 ? 208 LYS L CB 1 ATOM 5797 C CG . LYS B 2 208 ? -141.763 -195.140 267.780 1.00 95.48 ? 208 LYS L CG 1 ATOM 5798 C CD . LYS B 2 208 ? -140.720 -195.199 268.882 1.00 96.51 ? 208 LYS L CD 1 ATOM 5799 C CE . LYS B 2 208 ? -141.074 -194.232 269.996 1.00 105.72 ? 208 LYS L CE 1 ATOM 5800 N NZ . LYS B 2 208 ? -139.980 -194.111 270.999 1.00 107.74 ? 208 LYS L NZ 1 ATOM 5801 N N . SER B 2 209 ? -143.959 -198.782 269.543 1.00 96.59 ? 209 SER L N 1 ATOM 5802 C CA . SER B 2 209 ? -144.951 -199.799 269.845 1.00 93.76 ? 209 SER L CA 1 ATOM 5803 C C . SER B 2 209 ? -145.550 -199.617 271.229 1.00 98.01 ? 209 SER L C 1 ATOM 5804 O O . SER B 2 209 ? -145.012 -198.887 272.067 1.00 97.35 ? 209 SER L O 1 ATOM 5805 C CB . SER B 2 209 ? -144.329 -201.189 269.726 1.00 87.49 ? 209 SER L CB 1 ATOM 5806 O OG . SER B 2 209 ? -145.203 -202.173 270.239 1.00 94.26 ? 209 SER L OG 1 ATOM 5807 N N . PHE B 2 210 ? -146.679 -200.277 271.458 1.00 98.89 ? 210 PHE L N 1 ATOM 5808 C CA . PHE B 2 210 ? -147.311 -200.256 272.765 1.00 97.96 ? 210 PHE L CA 1 ATOM 5809 C C . PHE B 2 210 ? -148.201 -201.465 272.969 1.00 100.69 ? 210 PHE L C 1 ATOM 5810 O O . PHE B 2 210 ? -148.920 -201.880 272.066 1.00 103.31 ? 210 PHE L O 1 ATOM 5811 C CB . PHE B 2 210 ? -148.135 -198.982 272.942 1.00 97.90 ? 210 PHE L CB 1 ATOM 5812 C CG . PHE B 2 210 ? -149.393 -198.956 272.119 1.00 104.02 ? 210 PHE L CG 1 ATOM 5813 C CD1 . PHE B 2 210 ? -150.587 -199.442 272.633 1.00 98.99 ? 210 PHE L CD1 1 ATOM 5814 C CD2 . PHE B 2 210 ? -149.384 -198.447 270.829 1.00 104.53 ? 210 PHE L CD2 1 ATOM 5815 C CE1 . PHE B 2 210 ? -151.747 -199.423 271.878 1.00 101.42 ? 210 PHE L CE1 1 ATOM 5816 C CE2 . PHE B 2 210 ? -150.545 -198.424 270.071 1.00 101.28 ? 210 PHE L CE2 1 ATOM 5817 C CZ . PHE B 2 210 ? -151.728 -198.913 270.595 1.00 101.22 ? 210 PHE L CZ 1 ATOM 5818 N N . ASN B 2 211 ? -148.140 -202.030 274.165 1.00 104.86 ? 211 ASN L N 1 ATOM 5819 C CA . ASN B 2 211 ? -149.105 -203.029 274.581 1.00 104.16 ? 211 ASN L CA 1 ATOM 5820 C C . ASN B 2 211 ? -150.275 -202.336 275.255 1.00 105.54 ? 211 ASN L C 1 ATOM 5821 O O . ASN B 2 211 ? -150.156 -201.182 275.676 1.00 101.37 ? 211 ASN L O 1 ATOM 5822 C CB . ASN B 2 211 ? -148.460 -204.051 275.521 1.00 107.42 ? 211 ASN L CB 1 ATOM 5823 C CG . ASN B 2 211 ? -147.430 -204.930 274.820 1.00 113.70 ? 211 ASN L CG 1 ATOM 5824 O OD1 . ASN B 2 211 ? -147.577 -205.265 273.642 1.00 117.30 ? 211 ASN L OD1 1 ATOM 5825 N ND2 . ASN B 2 211 ? -146.383 -205.310 275.547 1.00 113.89 ? 211 ASN L ND2 1 ATOM 5826 N N . ARG B 2 212 ? -151.407 -203.026 275.350 1.00 108.19 ? 212 ARG L N 1 ATOM 5827 C CA . ARG B 2 212 ? -152.521 -202.530 276.155 1.00 114.41 ? 212 ARG L CA 1 ATOM 5828 C C . ARG B 2 212 ? -152.345 -202.892 277.645 1.00 123.97 ? 212 ARG L C 1 ATOM 5829 O O . ARG B 2 212 ? -152.830 -203.932 278.107 1.00 124.51 ? 212 ARG L O 1 ATOM 5830 C CB . ARG B 2 212 ? -153.833 -203.078 275.619 1.00 109.57 ? 212 ARG L CB 1 ATOM 5831 C CG . ARG B 2 212 ? -153.976 -202.865 274.130 1.00 113.13 ? 212 ARG L CG 1 ATOM 5832 C CD . ARG B 2 212 ? -155.224 -203.535 273.584 1.00 109.45 ? 212 ARG L CD 1 ATOM 5833 N NE . ARG B 2 212 ? -156.431 -202.923 274.118 1.00 107.87 ? 212 ARG L NE 1 ATOM 5834 C CZ . ARG B 2 212 ? -157.574 -203.575 274.283 1.00 111.48 ? 212 ARG L CZ 1 ATOM 5835 N NH1 . ARG B 2 212 ? -157.652 -204.865 273.952 1.00 108.68 ? 212 ARG L NH1 1 ATOM 5836 N NH2 . ARG B 2 212 ? -158.631 -202.941 274.784 1.00 108.67 ? 212 ARG L NH2 1 ATOM 5837 N N . ASN B 2 213 ? -151.634 -202.014 278.358 1.00 123.81 ? 213 ASN L N 1 ATOM 5838 C CA . ASN B 2 213 ? -151.305 -202.112 279.786 1.00 124.48 ? 213 ASN L CA 1 ATOM 5839 C C . ASN B 2 213 ? -151.979 -203.253 280.550 1.00 130.72 ? 213 ASN L C 1 ATOM 5840 O O . ASN B 2 213 ? -151.861 -203.360 281.777 1.00 134.60 ? 213 ASN L O 1 ATOM 5841 C CB . ASN B 2 213 ? -151.637 -200.774 280.468 1.00 129.71 ? 213 ASN L CB 1 ATOM 5842 C CG . ASN B 2 213 ? -153.069 -200.315 280.202 1.00 130.96 ? 213 ASN L CG 1 ATOM 5843 O OD1 . ASN B 2 213 ? -153.766 -200.872 279.350 1.00 131.78 ? 213 ASN L OD1 1 ATOM 5844 N ND2 . ASN B 2 213 ? -153.507 -199.289 280.927 1.00 129.18 ? 213 ASN L ND2 1 ATOM 5845 N N . GLU C 3 1 ? -153.195 -152.855 245.903 1.00 83.38 ? 1 GLU H N 1 ATOM 5846 C CA . GLU C 3 1 ? -153.178 -152.333 244.538 1.00 89.06 ? 1 GLU H CA 1 ATOM 5847 C C . GLU C 3 1 ? -154.298 -152.982 243.693 1.00 93.37 ? 1 GLU H C 1 ATOM 5848 O O . GLU C 3 1 ? -155.483 -152.802 243.991 1.00 91.69 ? 1 GLU H O 1 ATOM 5849 C CB . GLU C 3 1 ? -151.811 -152.571 243.901 1.00 94.69 ? 1 GLU H CB 1 ATOM 5850 N N . VAL C 3 2 ? -153.937 -153.713 242.636 1.00 88.31 ? 2 VAL H N 1 ATOM 5851 C CA . VAL C 3 2 ? -154.907 -154.579 241.981 1.00 84.06 ? 2 VAL H CA 1 ATOM 5852 C C . VAL C 3 2 ? -155.285 -155.701 242.930 1.00 85.36 ? 2 VAL H C 1 ATOM 5853 O O . VAL C 3 2 ? -154.412 -156.301 243.571 1.00 83.69 ? 2 VAL H O 1 ATOM 5854 C CB . VAL C 3 2 ? -154.374 -155.193 240.676 1.00 79.12 ? 2 VAL H CB 1 ATOM 5855 C CG1 . VAL C 3 2 ? -155.275 -156.315 240.233 1.00 76.54 ? 2 VAL H CG1 1 ATOM 5856 C CG2 . VAL C 3 2 ? -154.302 -154.161 239.600 1.00 80.22 ? 2 VAL H CG2 1 ATOM 5857 N N . GLN C 3 3 ? -156.578 -156.006 242.999 1.00 80.48 ? 3 GLN H N 1 ATOM 5858 C CA . GLN C 3 3 ? -157.031 -157.136 243.800 1.00 81.87 ? 3 GLN H CA 1 ATOM 5859 C C . GLN C 3 3 ? -158.202 -157.821 243.104 1.00 83.15 ? 3 GLN H C 1 ATOM 5860 O O . GLN C 3 3 ? -159.070 -157.164 242.517 1.00 78.94 ? 3 GLN H O 1 ATOM 5861 C CB . GLN C 3 3 ? -157.419 -156.690 245.212 1.00 71.85 ? 3 GLN H CB 1 ATOM 5862 N N . LEU C 3 4 ? -158.194 -159.150 243.137 1.00 79.21 ? 4 LEU H N 1 ATOM 5863 C CA . LEU C 3 4 ? -159.274 -159.947 242.574 1.00 76.21 ? 4 LEU H CA 1 ATOM 5864 C C . LEU C 3 4 ? -159.767 -160.893 243.653 1.00 82.39 ? 4 LEU H C 1 ATOM 5865 O O . LEU C 3 4 ? -158.967 -161.496 244.376 1.00 81.83 ? 4 LEU H O 1 ATOM 5866 C CB . LEU C 3 4 ? -158.805 -160.728 241.349 1.00 76.48 ? 4 LEU H CB 1 ATOM 5867 C CG . LEU C 3 4 ? -158.204 -159.917 240.203 1.00 72.89 ? 4 LEU H CG 1 ATOM 5868 C CD1 . LEU C 3 4 ? -157.678 -160.858 239.129 1.00 72.80 ? 4 LEU H CD1 1 ATOM 5869 C CD2 . LEU C 3 4 ? -159.232 -158.953 239.632 1.00 70.46 ? 4 LEU H CD2 1 ATOM 5870 N N . VAL C 3 5 ? -161.081 -161.028 243.768 1.00 82.96 ? 5 VAL H N 1 ATOM 5871 C CA . VAL C 3 5 ? -161.639 -161.854 244.823 1.00 81.49 ? 5 VAL H CA 1 ATOM 5872 C C . VAL C 3 5 ? -162.742 -162.746 244.290 1.00 81.62 ? 5 VAL H C 1 ATOM 5873 O O . VAL C 3 5 ? -163.842 -162.284 243.990 1.00 78.30 ? 5 VAL H O 1 ATOM 5874 C CB . VAL C 3 5 ? -162.196 -161.009 245.970 1.00 75.63 ? 5 VAL H CB 1 ATOM 5875 C CG1 . VAL C 3 5 ? -162.832 -161.906 247.002 1.00 74.56 ? 5 VAL H CG1 1 ATOM 5876 C CG2 . VAL C 3 5 ? -161.087 -160.182 246.592 1.00 66.96 ? 5 VAL H CG2 1 ATOM 5877 N N . GLU C 3 6 ? -162.422 -164.026 244.142 1.00 82.82 ? 6 GLU H N 1 ATOM 5878 C CA . GLU C 3 6 ? -163.408 -165.015 243.754 1.00 76.15 ? 6 GLU H CA 1 ATOM 5879 C C . GLU C 3 6 ? -164.283 -165.386 244.927 1.00 74.96 ? 6 GLU H C 1 ATOM 5880 O O . GLU C 3 6 ? -163.836 -165.357 246.072 1.00 81.36 ? 6 GLU H O 1 ATOM 5881 C CB . GLU C 3 6 ? -162.727 -166.255 243.187 1.00 77.09 ? 6 GLU H CB 1 ATOM 5882 C CG . GLU C 3 6 ? -161.806 -165.948 242.020 1.00 75.77 ? 6 GLU H CG 1 ATOM 5883 C CD . GLU C 3 6 ? -160.401 -165.625 242.467 1.00 76.31 ? 6 GLU H CD 1 ATOM 5884 O OE1 . GLU C 3 6 ? -160.216 -165.226 243.637 1.00 74.89 ? 6 GLU H OE1 1 ATOM 5885 O OE2 . GLU C 3 6 ? -159.474 -165.793 241.648 1.00 82.76 ? 6 GLU H OE2 1 ATOM 5886 N N . SER C 3 7 ? -165.526 -165.750 244.631 1.00 75.67 ? 7 SER H N 1 ATOM 5887 C CA . SER C 3 7 ? -166.467 -166.169 245.657 1.00 72.55 ? 7 SER H CA 1 ATOM 5888 C C . SER C 3 7 ? -167.555 -167.066 245.083 1.00 74.42 ? 7 SER H C 1 ATOM 5889 O O . SER C 3 7 ? -167.766 -167.103 243.868 1.00 74.52 ? 7 SER H O 1 ATOM 5890 C CB . SER C 3 7 ? -167.105 -164.954 246.308 1.00 71.50 ? 7 SER H CB 1 ATOM 5891 O OG . SER C 3 7 ? -167.986 -164.324 245.396 1.00 78.61 ? 7 SER H OG 1 ATOM 5892 N N . GLY C 3 8 ? -168.262 -167.768 245.963 1.00 72.83 ? 8 GLY H N 1 ATOM 5893 C CA . GLY C 3 8 ? -169.421 -168.544 245.556 1.00 70.79 ? 8 GLY H CA 1 ATOM 5894 C C . GLY C 3 8 ? -169.256 -170.047 245.480 1.00 77.25 ? 8 GLY H C 1 ATOM 5895 O O . GLY C 3 8 ? -170.232 -170.779 245.286 1.00 82.12 ? 8 GLY H O 1 ATOM 5896 N N . GLY C 3 9 ? -168.028 -170.525 245.632 1.00 75.41 ? 9 GLY H N 1 ATOM 5897 C CA . GLY C 3 9 ? -167.781 -171.948 245.530 1.00 72.43 ? 9 GLY H CA 1 ATOM 5898 C C . GLY C 3 9 ? -168.389 -172.670 246.712 1.00 77.29 ? 9 GLY H C 1 ATOM 5899 O O . GLY C 3 9 ? -168.620 -172.068 247.757 1.00 83.89 ? 9 GLY H O 1 ATOM 5900 N N . GLY C 3 10 ? -168.655 -173.960 246.546 1.00 75.63 ? 10 GLY H N 1 ATOM 5901 C CA . GLY C 3 10 ? -169.152 -174.787 247.629 1.00 69.73 ? 10 GLY H CA 1 ATOM 5902 C C . GLY C 3 10 ? -169.569 -176.140 247.099 1.00 73.34 ? 10 GLY H C 1 ATOM 5903 O O . GLY C 3 10 ? -169.392 -176.420 245.917 1.00 77.01 ? 10 GLY H O 1 ATOM 5904 N N . LEU C 3 11 ? -170.105 -176.995 247.965 1.00 73.84 ? 11 LEU H N 1 ATOM 5905 C CA . LEU C 3 11 ? -170.545 -178.319 247.536 1.00 68.26 ? 11 LEU H CA 1 ATOM 5906 C C . LEU C 3 11 ? -171.790 -178.233 246.651 1.00 71.71 ? 11 LEU H C 1 ATOM 5907 O O . LEU C 3 11 ? -172.699 -177.439 246.903 1.00 71.46 ? 11 LEU H O 1 ATOM 5908 C CB . LEU C 3 11 ? -170.812 -179.213 248.747 1.00 63.40 ? 11 LEU H CB 1 ATOM 5909 C CG . LEU C 3 11 ? -171.327 -180.630 248.505 1.00 70.04 ? 11 LEU H CG 1 ATOM 5910 C CD1 . LEU C 3 11 ? -170.562 -181.342 247.385 1.00 71.65 ? 11 LEU H CD1 1 ATOM 5911 C CD2 . LEU C 3 11 ? -171.254 -181.442 249.783 1.00 68.66 ? 11 LEU H CD2 1 ATOM 5912 N N . VAL C 3 12 ? -171.824 -179.060 245.615 1.00 68.46 ? 12 VAL H N 1 ATOM 5913 C CA . VAL C 3 12 ? -172.962 -179.121 244.712 1.00 69.65 ? 12 VAL H CA 1 ATOM 5914 C C . VAL C 3 12 ? -173.131 -180.560 244.253 1.00 77.31 ? 12 VAL H C 1 ATOM 5915 O O . VAL C 3 12 ? -172.138 -181.253 244.017 1.00 79.91 ? 12 VAL H O 1 ATOM 5916 C CB . VAL C 3 12 ? -172.782 -178.219 243.482 1.00 66.91 ? 12 VAL H CB 1 ATOM 5917 C CG1 . VAL C 3 12 ? -173.958 -178.394 242.535 1.00 68.51 ? 12 VAL H CG1 1 ATOM 5918 C CG2 . VAL C 3 12 ? -172.620 -176.777 243.893 1.00 64.52 ? 12 VAL H CG2 1 ATOM 5919 N N . LYS C 3 13 ? -174.376 -181.020 244.145 1.00 77.73 ? 13 LYS H N 1 ATOM 5920 C CA . LYS C 3 13 ? -174.637 -182.372 243.648 1.00 76.98 ? 13 LYS H CA 1 ATOM 5921 C C . LYS C 3 13 ? -174.477 -182.386 242.133 1.00 76.75 ? 13 LYS H C 1 ATOM 5922 O O . LYS C 3 13 ? -174.671 -181.353 241.483 1.00 77.00 ? 13 LYS H O 1 ATOM 5923 C CB . LYS C 3 13 ? -176.029 -182.851 244.072 1.00 77.33 ? 13 LYS H CB 1 ATOM 5924 C CG . LYS C 3 13 ? -176.201 -182.834 245.589 1.00 89.19 ? 13 LYS H CG 1 ATOM 5925 C CD . LYS C 3 13 ? -177.582 -183.271 246.062 1.00 92.44 ? 13 LYS H CD 1 ATOM 5926 C CE . LYS C 3 13 ? -177.592 -183.424 247.583 1.00 89.79 ? 13 LYS H CE 1 ATOM 5927 N NZ . LYS C 3 13 ? -176.662 -184.501 248.056 1.00 91.19 ? 13 LYS H NZ 1 ATOM 5928 N N . PRO C 3 14 ? -174.129 -183.551 241.569 1.00 77.90 ? 14 PRO H N 1 ATOM 5929 C CA . PRO C 3 14 ? -173.904 -183.616 240.124 1.00 74.37 ? 14 PRO H CA 1 ATOM 5930 C C . PRO C 3 14 ? -175.155 -183.243 239.358 1.00 75.84 ? 14 PRO H C 1 ATOM 5931 O O . PRO C 3 14 ? -176.260 -183.551 239.788 1.00 77.45 ? 14 PRO H O 1 ATOM 5932 C CB . PRO C 3 14 ? -173.539 -185.082 239.888 1.00 70.65 ? 14 PRO H CB 1 ATOM 5933 C CG . PRO C 3 14 ? -172.941 -185.533 241.180 1.00 72.82 ? 14 PRO H CG 1 ATOM 5934 C CD . PRO C 3 14 ? -173.652 -184.763 242.266 1.00 79.14 ? 14 PRO H CD 1 ATOM 5935 N N . GLY C 3 15 ? -174.961 -182.549 238.246 1.00 84.14 ? 15 GLY H N 1 ATOM 5936 C CA . GLY C 3 15 ? -176.050 -182.087 237.410 1.00 80.14 ? 15 GLY H CA 1 ATOM 5937 C C . GLY C 3 15 ? -176.556 -180.747 237.900 1.00 79.79 ? 15 GLY H C 1 ATOM 5938 O O . GLY C 3 15 ? -177.328 -180.080 237.214 1.00 84.10 ? 15 GLY H O 1 ATOM 5939 N N . GLY C 3 16 ? -176.082 -180.326 239.068 1.00 76.28 ? 16 GLY H N 1 ATOM 5940 C CA . GLY C 3 16 ? -176.578 -179.107 239.681 1.00 77.85 ? 16 GLY H CA 1 ATOM 5941 C C . GLY C 3 16 ? -175.898 -177.913 239.040 1.00 77.41 ? 16 GLY H C 1 ATOM 5942 O O . GLY C 3 16 ? -175.155 -178.073 238.077 1.00 80.84 ? 16 GLY H O 1 ATOM 5943 N N . SER C 3 17 ? -176.144 -176.715 239.558 1.00 75.53 ? 17 SER H N 1 ATOM 5944 C CA . SER C 3 17 ? -175.541 -175.523 238.974 1.00 76.70 ? 17 SER H CA 1 ATOM 5945 C C . SER C 3 17 ? -175.252 -174.448 240.004 1.00 76.72 ? 17 SER H C 1 ATOM 5946 O O . SER C 3 17 ? -175.902 -174.366 241.038 1.00 85.52 ? 17 SER H O 1 ATOM 5947 C CB . SER C 3 17 ? -176.430 -174.963 237.863 1.00 80.11 ? 17 SER H CB 1 ATOM 5948 O OG . SER C 3 17 ? -177.760 -174.824 238.279 1.00 77.23 ? 17 SER H OG 1 ATOM 5949 N N . LEU C 3 18 ? -174.277 -173.605 239.700 1.00 76.31 ? 18 LEU H N 1 ATOM 5950 C CA . LEU C 3 18 ? -173.788 -172.651 240.675 1.00 72.53 ? 18 LEU H CA 1 ATOM 5951 C C . LEU C 3 18 ? -173.124 -171.488 239.950 1.00 76.28 ? 18 LEU H C 1 ATOM 5952 O O . LEU C 3 18 ? -172.709 -171.635 238.796 1.00 79.95 ? 18 LEU H O 1 ATOM 5953 C CB . LEU C 3 18 ? -172.827 -173.353 241.635 1.00 77.21 ? 18 LEU H CB 1 ATOM 5954 C CG . LEU C 3 18 ? -172.173 -172.567 242.766 1.00 83.00 ? 18 LEU H CG 1 ATOM 5955 C CD1 . LEU C 3 18 ? -173.222 -171.807 243.593 1.00 90.61 ? 18 LEU H CD1 1 ATOM 5956 C CD2 . LEU C 3 18 ? -171.382 -173.513 243.629 1.00 75.52 ? 18 LEU H CD2 1 ATOM 5957 N N . LYS C 3 19 ? -173.043 -170.329 240.601 1.00 76.03 ? 19 LYS H N 1 ATOM 5958 C CA . LYS C 3 19 ? -172.519 -169.131 239.945 1.00 74.63 ? 19 LYS H CA 1 ATOM 5959 C C . LYS C 3 19 ? -171.368 -168.554 240.756 1.00 76.69 ? 19 LYS H C 1 ATOM 5960 O O . LYS C 3 19 ? -171.561 -168.044 241.864 1.00 77.90 ? 19 LYS H O 1 ATOM 5961 C CB . LYS C 3 19 ? -173.631 -168.088 239.755 1.00 77.81 ? 19 LYS H CB 1 ATOM 5962 C CG . LYS C 3 19 ? -173.218 -166.755 239.122 1.00 80.07 ? 19 LYS H CG 1 ATOM 5963 C CD . LYS C 3 19 ? -174.433 -165.826 238.978 1.00 82.47 ? 19 LYS H CD 1 ATOM 5964 C CE . LYS C 3 19 ? -174.037 -164.421 238.520 1.00 95.60 ? 19 LYS H CE 1 ATOM 5965 N NZ . LYS C 3 19 ? -175.167 -163.618 237.923 1.00 96.63 ? 19 LYS H NZ 1 ATOM 5966 N N . LEU C 3 20 ? -170.161 -168.689 240.218 1.00 77.41 ? 20 LEU H N 1 ATOM 5967 C CA . LEU C 3 20 ? -168.973 -168.083 240.806 1.00 74.85 ? 20 LEU H CA 1 ATOM 5968 C C . LEU C 3 20 ? -168.905 -166.610 240.451 1.00 70.30 ? 20 LEU H C 1 ATOM 5969 O O . LEU C 3 20 ? -169.449 -166.195 239.428 1.00 71.99 ? 20 LEU H O 1 ATOM 5970 C CB . LEU C 3 20 ? -167.717 -168.811 240.338 1.00 76.35 ? 20 LEU H CB 1 ATOM 5971 C CG . LEU C 3 20 ? -167.733 -170.291 240.707 1.00 80.05 ? 20 LEU H CG 1 ATOM 5972 C CD1 . LEU C 3 20 ? -166.456 -170.992 240.232 1.00 77.91 ? 20 LEU H CD1 1 ATOM 5973 C CD2 . LEU C 3 20 ? -167.904 -170.413 242.204 1.00 76.66 ? 20 LEU H CD2 1 ATOM 5974 N N . SER C 3 21 ? -168.221 -165.826 241.282 1.00 69.31 ? 21 SER H N 1 ATOM 5975 C CA . SER C 3 21 ? -168.098 -164.390 241.040 1.00 73.03 ? 21 SER H CA 1 ATOM 5976 C C . SER C 3 21 ? -166.735 -163.876 241.435 1.00 75.41 ? 21 SER H C 1 ATOM 5977 O O . SER C 3 21 ? -166.164 -164.337 242.427 1.00 76.28 ? 21 SER H O 1 ATOM 5978 C CB . SER C 3 21 ? -169.169 -163.612 241.812 1.00 70.21 ? 21 SER H CB 1 ATOM 5979 O OG . SER C 3 21 ? -170.459 -163.881 241.297 1.00 70.59 ? 21 SER H OG 1 ATOM 5980 N N . CYS C 3 22 ? -166.225 -162.907 240.677 1.00 73.57 ? 22 CYS H N 1 ATOM 5981 C CA . CYS C 3 22 ? -164.927 -162.317 240.987 1.00 75.70 ? 22 CYS H CA 1 ATOM 5982 C C . CYS C 3 22 ? -165.037 -160.806 241.083 1.00 82.32 ? 22 CYS H C 1 ATOM 5983 O O . CYS C 3 22 ? -165.431 -160.129 240.129 1.00 83.43 ? 22 CYS H O 1 ATOM 5984 C CB . CYS C 3 22 ? -163.888 -162.682 239.932 1.00 82.38 ? 22 CYS H CB 1 ATOM 5985 S SG . CYS C 3 22 ? -162.189 -162.099 240.288 1.00 91.07 ? 22 CYS H SG 1 ATOM 5986 N N . ALA C 3 23 ? -164.680 -160.278 242.244 1.00 82.71 ? 23 ALA H N 1 ATOM 5987 C CA . ALA C 3 23 ? -164.786 -158.856 242.496 1.00 73.93 ? 23 ALA H CA 1 ATOM 5988 C C . ALA C 3 23 ? -163.482 -158.150 242.179 1.00 76.18 ? 23 ALA H C 1 ATOM 5989 O O . ALA C 3 23 ? -162.565 -158.126 243.001 1.00 77.82 ? 23 ALA H O 1 ATOM 5990 C CB . ALA C 3 23 ? -165.185 -158.612 243.935 1.00 71.93 ? 23 ALA H CB 1 ATOM 5991 N N . ALA C 3 24 ? -163.405 -157.576 240.984 1.00 74.77 ? 24 ALA H N 1 ATOM 5992 C CA . ALA C 3 24 ? -162.239 -156.796 240.573 1.00 76.58 ? 24 ALA H CA 1 ATOM 5993 C C . ALA C 3 24 ? -162.175 -155.448 241.276 1.00 78.78 ? 24 ALA H C 1 ATOM 5994 O O . ALA C 3 24 ? -163.207 -154.814 241.501 1.00 86.21 ? 24 ALA H O 1 ATOM 5995 C CB . ALA C 3 24 ? -162.240 -156.595 239.065 1.00 70.77 ? 24 ALA H CB 1 ATOM 5996 N N . SER C 3 25 ? -160.966 -155.003 241.597 1.00 75.68 ? 25 SER H N 1 ATOM 5997 C CA . SER C 3 25 ? -160.750 -153.678 242.155 1.00 74.90 ? 25 SER H CA 1 ATOM 5998 C C . SER C 3 25 ? -159.287 -153.260 242.024 1.00 81.15 ? 25 SER H C 1 ATOM 5999 O O . SER C 3 25 ? -158.406 -154.118 241.906 1.00 88.51 ? 25 SER H O 1 ATOM 6000 C CB . SER C 3 25 ? -161.165 -153.649 243.612 1.00 79.70 ? 25 SER H CB 1 ATOM 6001 O OG . SER C 3 25 ? -160.181 -154.239 244.429 1.00 84.47 ? 25 SER H OG 1 ATOM 6002 N N . GLY C 3 26 ? -159.025 -151.954 242.070 1.00 80.41 ? 26 GLY H N 1 ATOM 6003 C CA . GLY C 3 26 ? -157.663 -151.430 242.017 1.00 82.78 ? 26 GLY H CA 1 ATOM 6004 C C . GLY C 3 26 ? -157.091 -151.191 240.630 1.00 80.45 ? 26 GLY H C 1 ATOM 6005 O O . GLY C 3 26 ? -155.910 -150.864 240.478 1.00 85.41 ? 26 GLY H O 1 ATOM 6006 N N . PHE C 3 27 ? -157.933 -151.369 239.620 1.00 76.08 ? 27 PHE H N 1 ATOM 6007 C CA . PHE C 3 27 ? -157.556 -151.150 238.228 1.00 74.95 ? 27 PHE H CA 1 ATOM 6008 C C . PHE C 3 27 ? -158.842 -150.965 237.433 1.00 75.62 ? 27 PHE H C 1 ATOM 6009 O O . PHE C 3 27 ? -159.935 -151.213 237.954 1.00 83.01 ? 27 PHE H O 1 ATOM 6010 C CB . PHE C 3 27 ? -156.744 -152.324 237.676 1.00 78.49 ? 27 PHE H CB 1 ATOM 6011 C CG . PHE C 3 27 ? -157.543 -153.597 237.537 1.00 77.83 ? 27 PHE H CG 1 ATOM 6012 C CD1 . PHE C 3 27 ? -158.223 -153.886 236.355 1.00 73.02 ? 27 PHE H CD1 1 ATOM 6013 C CD2 . PHE C 3 27 ? -157.635 -154.489 238.600 1.00 72.55 ? 27 PHE H CD2 1 ATOM 6014 C CE1 . PHE C 3 27 ? -158.968 -155.035 236.231 1.00 70.64 ? 27 PHE H CE1 1 ATOM 6015 C CE2 . PHE C 3 27 ? -158.373 -155.644 238.479 1.00 74.70 ? 27 PHE H CE2 1 ATOM 6016 C CZ . PHE C 3 27 ? -159.041 -155.918 237.292 1.00 76.45 ? 27 PHE H CZ 1 ATOM 6017 N N . THR C 3 28 ? -158.727 -150.537 236.183 1.00 68.18 ? 28 THR H N 1 ATOM 6018 C CA . THR C 3 28 ? -159.916 -150.265 235.386 1.00 79.78 ? 28 THR H CA 1 ATOM 6019 C C . THR C 3 28 ? -160.447 -151.520 234.708 1.00 83.12 ? 28 THR H C 1 ATOM 6020 O O . THR C 3 28 ? -160.025 -151.880 233.606 1.00 82.56 ? 28 THR H O 1 ATOM 6021 C CB . THR C 3 28 ? -159.652 -149.207 234.329 1.00 81.86 ? 28 THR H CB 1 ATOM 6022 O OG1 . THR C 3 28 ? -159.350 -147.974 234.988 1.00 86.23 ? 28 THR H OG1 1 ATOM 6023 C CG2 . THR C 3 28 ? -160.881 -149.033 233.466 1.00 74.93 ? 28 THR H CG2 1 ATOM 6024 N N . PHE C 3 29 ? -161.422 -152.139 235.361 1.00 82.61 ? 29 PHE H N 1 ATOM 6025 C CA . PHE C 3 29 ? -161.900 -153.464 235.008 1.00 78.04 ? 29 PHE H CA 1 ATOM 6026 C C . PHE C 3 29 ? -162.425 -153.535 233.584 1.00 82.78 ? 29 PHE H C 1 ATOM 6027 O O . PHE C 3 29 ? -162.353 -154.587 232.948 1.00 82.33 ? 29 PHE H O 1 ATOM 6028 C CB . PHE C 3 29 ? -162.995 -153.884 235.980 1.00 79.73 ? 29 PHE H CB 1 ATOM 6029 C CG . PHE C 3 29 ? -163.575 -155.238 235.703 1.00 81.47 ? 29 PHE H CG 1 ATOM 6030 C CD1 . PHE C 3 29 ? -162.896 -156.386 236.077 1.00 75.92 ? 29 PHE H CD1 1 ATOM 6031 C CD2 . PHE C 3 29 ? -164.818 -155.364 235.101 1.00 84.48 ? 29 PHE H CD2 1 ATOM 6032 C CE1 . PHE C 3 29 ? -163.433 -157.632 235.845 1.00 79.87 ? 29 PHE H CE1 1 ATOM 6033 C CE2 . PHE C 3 29 ? -165.366 -156.616 234.858 1.00 85.80 ? 29 PHE H CE2 1 ATOM 6034 C CZ . PHE C 3 29 ? -164.674 -157.754 235.233 1.00 83.96 ? 29 PHE H CZ 1 ATOM 6035 N N . SER C 3 30 ? -162.949 -152.422 233.077 1.00 90.88 ? 30 SER H N 1 ATOM 6036 C CA . SER C 3 30 ? -163.494 -152.403 231.724 1.00 83.70 ? 30 SER H CA 1 ATOM 6037 C C . SER C 3 30 ? -162.403 -152.646 230.683 1.00 81.68 ? 30 SER H C 1 ATOM 6038 O O . SER C 3 30 ? -162.664 -153.250 229.650 1.00 86.96 ? 30 SER H O 1 ATOM 6039 C CB . SER C 3 30 ? -164.208 -151.080 231.443 1.00 70.76 ? 30 SER H CB 1 ATOM 6040 N N . SER C 3 31 ? -161.178 -152.211 230.973 1.00 77.04 ? 31 SER H N 1 ATOM 6041 C CA . SER C 3 31 ? -160.095 -152.251 229.986 1.00 77.06 ? 31 SER H CA 1 ATOM 6042 C C . SER C 3 31 ? -159.484 -153.634 229.741 1.00 85.87 ? 31 SER H C 1 ATOM 6043 O O . SER C 3 31 ? -158.837 -153.859 228.710 1.00 79.47 ? 31 SER H O 1 ATOM 6044 C CB . SER C 3 31 ? -158.986 -151.297 230.412 1.00 81.26 ? 31 SER H CB 1 ATOM 6045 O OG . SER C 3 31 ? -159.506 -150.001 230.603 1.00 85.76 ? 31 SER H OG 1 ATOM 6046 N N . TYR C 3 32 ? -159.676 -154.554 230.685 1.00 89.99 ? 32 TYR H N 1 ATOM 6047 C CA . TYR C 3 32 ? -158.992 -155.841 230.610 1.00 83.19 ? 32 TYR H CA 1 ATOM 6048 C C . TYR C 3 32 ? -159.903 -157.027 230.368 1.00 77.29 ? 32 TYR H C 1 ATOM 6049 O O . TYR C 3 32 ? -160.967 -157.131 230.955 1.00 79.68 ? 32 TYR H O 1 ATOM 6050 C CB . TYR C 3 32 ? -158.214 -156.079 231.888 1.00 79.55 ? 32 TYR H CB 1 ATOM 6051 C CG . TYR C 3 32 ? -157.175 -155.026 232.174 1.00 82.42 ? 32 TYR H CG 1 ATOM 6052 C CD1 . TYR C 3 32 ? -155.964 -155.028 231.519 1.00 82.59 ? 32 TYR H CD1 1 ATOM 6053 C CD2 . TYR C 3 32 ? -157.402 -154.040 233.114 1.00 83.35 ? 32 TYR H CD2 1 ATOM 6054 C CE1 . TYR C 3 32 ? -155.008 -154.079 231.790 1.00 83.86 ? 32 TYR H CE1 1 ATOM 6055 C CE2 . TYR C 3 32 ? -156.454 -153.081 233.385 1.00 83.51 ? 32 TYR H CE2 1 ATOM 6056 C CZ . TYR C 3 32 ? -155.256 -153.108 232.720 1.00 82.46 ? 32 TYR H CZ 1 ATOM 6057 O OH . TYR C 3 32 ? -154.295 -152.162 232.987 1.00 89.18 ? 32 TYR H OH 1 ATOM 6058 N N . ALA C 3 33 ? -159.472 -157.921 229.491 1.00 77.73 ? 33 ALA H N 1 ATOM 6059 C CA . ALA C 3 33 ? -160.100 -159.226 229.348 1.00 76.90 ? 33 ALA H CA 1 ATOM 6060 C C . ALA C 3 33 ? -159.807 -160.059 230.587 1.00 80.87 ? 33 ALA H C 1 ATOM 6061 O O . ALA C 3 33 ? -158.763 -159.900 231.227 1.00 82.25 ? 33 ALA H O 1 ATOM 6062 C CB . ALA C 3 33 ? -159.603 -159.937 228.103 1.00 70.39 ? 33 ALA H CB 1 ATOM 6063 N N . MET C 3 34 ? -160.728 -160.949 230.923 1.00 76.63 ? 34 MET H N 1 ATOM 6064 C CA . MET C 3 34 ? -160.589 -161.772 232.110 1.00 74.89 ? 34 MET H CA 1 ATOM 6065 C C . MET C 3 34 ? -160.771 -163.241 231.748 1.00 75.37 ? 34 MET H C 1 ATOM 6066 O O . MET C 3 34 ? -161.471 -163.567 230.780 1.00 74.42 ? 34 MET H O 1 ATOM 6067 C CB . MET C 3 34 ? -161.612 -161.353 233.152 1.00 73.99 ? 34 MET H CB 1 ATOM 6068 C CG . MET C 3 34 ? -161.581 -159.884 233.451 1.00 68.75 ? 34 MET H CG 1 ATOM 6069 S SD . MET C 3 34 ? -160.189 -159.510 234.494 1.00 75.70 ? 34 MET H SD 1 ATOM 6070 C CE . MET C 3 34 ? -160.549 -160.493 235.948 1.00 73.33 ? 34 MET H CE 1 ATOM 6071 N N . SER C 3 35 ? -160.144 -164.132 232.509 1.00 66.98 ? 35 SER H N 1 ATOM 6072 C CA . SER C 3 35 ? -160.357 -165.561 232.293 1.00 66.68 ? 35 SER H CA 1 ATOM 6073 C C . SER C 3 35 ? -160.605 -166.284 233.593 1.00 69.16 ? 35 SER H C 1 ATOM 6074 O O . SER C 3 35 ? -160.125 -165.872 234.653 1.00 69.47 ? 35 SER H O 1 ATOM 6075 C CB . SER C 3 35 ? -159.165 -166.195 231.587 1.00 66.10 ? 35 SER H CB 1 ATOM 6076 O OG . SER C 3 35 ? -159.134 -165.833 230.224 1.00 73.35 ? 35 SER H OG 1 ATOM 6077 N N . TRP C 3 36 ? -161.380 -167.354 233.510 1.00 63.08 ? 36 TRP H N 1 ATOM 6078 C CA . TRP C 3 36 ? -161.464 -168.289 234.609 1.00 68.68 ? 36 TRP H CA 1 ATOM 6079 C C . TRP C 3 36 ? -160.486 -169.430 234.334 1.00 71.09 ? 36 TRP H C 1 ATOM 6080 O O . TRP C 3 36 ? -160.519 -170.048 233.256 1.00 64.73 ? 36 TRP H O 1 ATOM 6081 C CB . TRP C 3 36 ? -162.892 -168.815 234.785 1.00 72.81 ? 36 TRP H CB 1 ATOM 6082 C CG . TRP C 3 36 ? -163.826 -167.793 235.352 1.00 75.63 ? 36 TRP H CG 1 ATOM 6083 C CD1 . TRP C 3 36 ? -164.692 -166.989 234.657 1.00 73.66 ? 36 TRP H CD1 1 ATOM 6084 C CD2 . TRP C 3 36 ? -163.984 -167.447 236.736 1.00 72.76 ? 36 TRP H CD2 1 ATOM 6085 N NE1 . TRP C 3 36 ? -165.372 -166.166 235.524 1.00 71.03 ? 36 TRP H NE1 1 ATOM 6086 C CE2 . TRP C 3 36 ? -164.958 -166.432 236.804 1.00 70.83 ? 36 TRP H CE2 1 ATOM 6087 C CE3 . TRP C 3 36 ? -163.399 -167.902 237.922 1.00 71.76 ? 36 TRP H CE3 1 ATOM 6088 C CZ2 . TRP C 3 36 ? -165.355 -165.865 238.009 1.00 70.51 ? 36 TRP H CZ2 1 ATOM 6089 C CZ3 . TRP C 3 36 ? -163.803 -167.339 239.121 1.00 73.49 ? 36 TRP H CZ3 1 ATOM 6090 C CH2 . TRP C 3 36 ? -164.769 -166.330 239.153 1.00 71.22 ? 36 TRP H CH2 1 ATOM 6091 N N . VAL C 3 37 ? -159.604 -169.683 235.302 1.00 63.73 ? 37 VAL H N 1 ATOM 6092 C CA . VAL C 3 37 ? -158.705 -170.833 235.264 1.00 65.39 ? 37 VAL H CA 1 ATOM 6093 C C . VAL C 3 37 ? -158.896 -171.705 236.506 1.00 69.10 ? 37 VAL H C 1 ATOM 6094 O O . VAL C 3 37 ? -158.888 -171.206 237.634 1.00 69.69 ? 37 VAL H O 1 ATOM 6095 C CB . VAL C 3 37 ? -157.233 -170.411 235.186 1.00 66.92 ? 37 VAL H CB 1 ATOM 6096 C CG1 . VAL C 3 37 ? -156.349 -171.638 235.231 1.00 71.75 ? 37 VAL H CG1 1 ATOM 6097 C CG2 . VAL C 3 37 ? -156.967 -169.608 233.942 1.00 66.42 ? 37 VAL H CG2 1 ATOM 6098 N N . ARG C 3 38 ? -159.073 -173.005 236.309 1.00 68.26 ? 38 ARG H N 1 ATOM 6099 C CA . ARG C 3 38 ? -159.295 -173.882 237.451 1.00 68.82 ? 38 ARG H CA 1 ATOM 6100 C C . ARG C 3 38 ? -158.090 -174.765 237.749 1.00 66.60 ? 38 ARG H C 1 ATOM 6101 O O . ARG C 3 38 ? -157.255 -174.995 236.885 1.00 66.85 ? 38 ARG H O 1 ATOM 6102 C CB . ARG C 3 38 ? -160.546 -174.738 237.240 1.00 66.65 ? 38 ARG H CB 1 ATOM 6103 C CG . ARG C 3 38 ? -160.560 -175.641 236.025 1.00 67.32 ? 38 ARG H CG 1 ATOM 6104 C CD . ARG C 3 38 ? -161.978 -176.168 235.857 1.00 69.72 ? 38 ARG H CD 1 ATOM 6105 N NE . ARG C 3 38 ? -162.098 -177.282 234.919 1.00 70.83 ? 38 ARG H NE 1 ATOM 6106 C CZ . ARG C 3 38 ? -163.261 -177.842 234.597 1.00 75.21 ? 38 ARG H CZ 1 ATOM 6107 N NH1 . ARG C 3 38 ? -164.400 -177.390 235.131 1.00 72.55 ? 38 ARG H NH1 1 ATOM 6108 N NH2 . ARG C 3 38 ? -163.294 -178.855 233.745 1.00 80.47 ? 38 ARG H NH2 1 ATOM 6109 N N . GLN C 3 39 ? -157.989 -175.227 238.990 1.00 63.24 ? 39 GLN H N 1 ATOM 6110 C CA . GLN C 3 39 ? -156.958 -176.180 239.373 1.00 66.87 ? 39 GLN H CA 1 ATOM 6111 C C . GLN C 3 39 ? -157.604 -177.358 240.101 1.00 66.50 ? 39 GLN H C 1 ATOM 6112 O O . GLN C 3 39 ? -158.179 -177.207 241.173 1.00 67.45 ? 39 GLN H O 1 ATOM 6113 C CB . GLN C 3 39 ? -155.888 -175.503 240.238 1.00 63.33 ? 39 GLN H CB 1 ATOM 6114 C CG . GLN C 3 39 ? -154.645 -176.357 240.454 1.00 65.14 ? 39 GLN H CG 1 ATOM 6115 C CD . GLN C 3 39 ? -153.462 -175.550 241.009 1.00 67.73 ? 39 GLN H CD 1 ATOM 6116 O OE1 . GLN C 3 39 ? -153.638 -174.637 241.818 1.00 74.51 ? 39 GLN H OE1 1 ATOM 6117 N NE2 . GLN C 3 39 ? -152.260 -175.881 240.564 1.00 66.43 ? 39 GLN H NE2 1 ATOM 6118 N N . SER C 3 40 ? -157.511 -178.534 239.501 1.00 70.49 ? 40 SER H N 1 ATOM 6119 C CA . SER C 3 40 ? -158.104 -179.735 240.062 1.00 68.35 ? 40 SER H CA 1 ATOM 6120 C C . SER C 3 40 ? -157.350 -180.135 241.318 1.00 73.38 ? 40 SER H C 1 ATOM 6121 O O . SER C 3 40 ? -156.252 -179.633 241.570 1.00 72.40 ? 40 SER H O 1 ATOM 6122 C CB . SER C 3 40 ? -158.095 -180.883 239.053 1.00 65.63 ? 40 SER H CB 1 ATOM 6123 O OG . SER C 3 40 ? -156.771 -181.278 238.727 1.00 72.88 ? 40 SER H OG 1 ATOM 6124 N N . PRO C 3 41 ? -157.962 -180.991 242.148 1.00 74.77 ? 41 PRO H N 1 ATOM 6125 C CA . PRO C 3 41 ? -157.297 -181.463 243.362 1.00 74.04 ? 41 PRO H CA 1 ATOM 6126 C C . PRO C 3 41 ? -155.979 -182.120 243.024 1.00 71.86 ? 41 PRO H C 1 ATOM 6127 O O . PRO C 3 41 ? -155.136 -182.202 243.907 1.00 78.55 ? 41 PRO H O 1 ATOM 6128 C CB . PRO C 3 41 ? -158.286 -182.459 243.955 1.00 66.70 ? 41 PRO H CB 1 ATOM 6129 C CG . PRO C 3 41 ? -159.268 -182.742 242.867 1.00 69.64 ? 41 PRO H CG 1 ATOM 6130 C CD . PRO C 3 41 ? -159.330 -181.513 242.033 1.00 65.45 ? 41 PRO H CD 1 ATOM 6131 N N . GLU C 3 42 ? -155.826 -182.624 241.802 1.00 70.43 ? 42 GLU H N 1 ATOM 6132 C CA . GLU C 3 42 ? -154.544 -183.163 241.347 1.00 76.11 ? 42 GLU H CA 1 ATOM 6133 C C . GLU C 3 42 ? -153.582 -182.073 240.818 1.00 75.63 ? 42 GLU H C 1 ATOM 6134 O O . GLU C 3 42 ? -152.567 -182.383 240.191 1.00 72.11 ? 42 GLU H O 1 ATOM 6135 C CB . GLU C 3 42 ? -154.787 -184.230 240.286 1.00 76.00 ? 42 GLU H CB 1 ATOM 6136 C CG . GLU C 3 42 ? -155.794 -185.253 240.774 1.00 80.40 ? 42 GLU H CG 1 ATOM 6137 C CD . GLU C 3 42 ? -155.860 -186.509 239.919 1.00 89.91 ? 42 GLU H CD 1 ATOM 6138 O OE1 . GLU C 3 42 ? -155.644 -186.408 238.685 1.00 91.20 ? 42 GLU H OE1 1 ATOM 6139 O OE2 . GLU C 3 42 ? -156.144 -187.595 240.490 1.00 86.06 ? 42 GLU H OE2 1 ATOM 6140 N N . LYS C 3 43 ? -153.912 -180.808 241.089 1.00 74.86 ? 43 LYS H N 1 ATOM 6141 C CA . LYS C 3 43 ? -153.008 -179.662 240.892 1.00 69.40 ? 43 LYS H CA 1 ATOM 6142 C C . LYS C 3 43 ? -152.768 -179.283 239.428 1.00 68.27 ? 43 LYS H C 1 ATOM 6143 O O . LYS C 3 43 ? -151.926 -178.433 239.133 1.00 64.22 ? 43 LYS H O 1 ATOM 6144 C CB . LYS C 3 43 ? -151.657 -179.930 241.566 1.00 64.32 ? 43 LYS H CB 1 ATOM 6145 C CG . LYS C 3 43 ? -151.681 -179.968 243.082 1.00 66.59 ? 43 LYS H CG 1 ATOM 6146 C CD . LYS C 3 43 ? -152.338 -178.686 243.650 1.00 87.63 ? 43 LYS H CD 1 ATOM 6147 C CE . LYS C 3 43 ? -151.423 -177.939 244.662 1.00 86.81 ? 43 LYS H CE 1 ATOM 6148 N NZ . LYS C 3 43 ? -151.923 -176.565 245.061 1.00 74.12 ? 43 LYS H NZ 1 ATOM 6149 N N . ARG C 3 44 ? -153.507 -179.904 238.515 1.00 70.88 ? 44 ARG H N 1 ATOM 6150 C CA . ARG C 3 44 ? -153.434 -179.528 237.105 1.00 70.84 ? 44 ARG H CA 1 ATOM 6151 C C . ARG C 3 44 ? -154.120 -178.181 236.867 1.00 71.14 ? 44 ARG H C 1 ATOM 6152 O O . ARG C 3 44 ? -155.262 -177.972 237.286 1.00 67.82 ? 44 ARG H O 1 ATOM 6153 C CB . ARG C 3 44 ? -154.069 -180.618 236.236 1.00 68.29 ? 44 ARG H CB 1 ATOM 6154 C CG . ARG C 3 44 ? -153.603 -180.642 234.796 1.00 81.29 ? 44 ARG H CG 1 ATOM 6155 C CD . ARG C 3 44 ? -154.369 -181.693 233.967 1.00 95.31 ? 44 ARG H CD 1 ATOM 6156 N NE . ARG C 3 44 ? -154.380 -181.361 232.537 1.00 97.92 ? 44 ARG H NE 1 ATOM 6157 C CZ . ARG C 3 44 ? -155.443 -180.913 231.873 1.00 93.90 ? 44 ARG H CZ 1 ATOM 6158 N NH1 . ARG C 3 44 ? -156.612 -180.753 232.489 1.00 96.02 ? 44 ARG H NH1 1 ATOM 6159 N NH2 . ARG C 3 44 ? -155.338 -180.630 230.586 1.00 103.74 ? 44 ARG H NH2 1 ATOM 6160 N N . LEU C 3 45 ? -153.437 -177.277 236.180 1.00 69.39 ? 45 LEU H N 1 ATOM 6161 C CA . LEU C 3 45 ? -154.068 -176.033 235.774 1.00 65.52 ? 45 LEU H CA 1 ATOM 6162 C C . LEU C 3 45 ? -154.775 -176.201 234.426 1.00 72.81 ? 45 LEU H C 1 ATOM 6163 O O . LEU C 3 45 ? -154.204 -176.716 233.464 1.00 76.93 ? 45 LEU H O 1 ATOM 6164 C CB . LEU C 3 45 ? -153.036 -174.917 235.705 1.00 63.68 ? 45 LEU H CB 1 ATOM 6165 C CG . LEU C 3 45 ? -152.684 -174.253 237.025 1.00 64.79 ? 45 LEU H CG 1 ATOM 6166 C CD1 . LEU C 3 45 ? -151.603 -173.254 236.782 1.00 64.39 ? 45 LEU H CD1 1 ATOM 6167 C CD2 . LEU C 3 45 ? -153.902 -173.580 237.596 1.00 66.63 ? 45 LEU H CD2 1 ATOM 6168 N N . GLU C 3 46 ? -156.021 -175.750 234.359 1.00 73.65 ? 46 GLU H N 1 ATOM 6169 C CA . GLU C 3 46 ? -156.809 -175.852 233.141 1.00 72.14 ? 46 GLU H CA 1 ATOM 6170 C C . GLU C 3 46 ? -157.611 -174.566 232.910 1.00 74.84 ? 46 GLU H C 1 ATOM 6171 O O . GLU C 3 46 ? -158.433 -174.157 233.739 1.00 71.44 ? 46 GLU H O 1 ATOM 6172 C CB . GLU C 3 46 ? -157.726 -177.074 233.207 1.00 62.93 ? 46 GLU H CB 1 ATOM 6173 C CG . GLU C 3 46 ? -158.748 -177.141 232.097 1.00 75.23 ? 46 GLU H CG 1 ATOM 6174 C CD . GLU C 3 46 ? -159.872 -178.163 232.356 1.00 93.30 ? 46 GLU H CD 1 ATOM 6175 O OE1 . GLU C 3 46 ? -160.054 -178.622 233.525 1.00 91.41 ? 46 GLU H OE1 1 ATOM 6176 O OE2 . GLU C 3 46 ? -160.582 -178.496 231.369 1.00 95.46 ? 46 GLU H OE2 1 ATOM 6177 N N . TRP C 3 47 ? -157.329 -173.907 231.791 1.00 71.27 ? 47 TRP H N 1 ATOM 6178 C CA . TRP C 3 47 ? -158.048 -172.699 231.419 1.00 68.47 ? 47 TRP H CA 1 ATOM 6179 C C . TRP C 3 47 ? -159.484 -173.070 231.087 1.00 70.43 ? 47 TRP H C 1 ATOM 6180 O O . TRP C 3 47 ? -159.735 -174.120 230.507 1.00 77.20 ? 47 TRP H O 1 ATOM 6181 C CB . TRP C 3 47 ? -157.356 -172.009 230.243 1.00 68.63 ? 47 TRP H CB 1 ATOM 6182 C CG . TRP C 3 47 ? -158.122 -170.883 229.647 1.00 67.83 ? 47 TRP H CG 1 ATOM 6183 C CD1 . TRP C 3 47 ? -158.125 -169.583 230.057 1.00 68.79 ? 47 TRP H CD1 1 ATOM 6184 C CD2 . TRP C 3 47 ? -158.992 -170.950 228.510 1.00 65.42 ? 47 TRP H CD2 1 ATOM 6185 N NE1 . TRP C 3 47 ? -158.949 -168.830 229.239 1.00 67.67 ? 47 TRP H NE1 1 ATOM 6186 C CE2 . TRP C 3 47 ? -159.486 -169.648 228.282 1.00 64.51 ? 47 TRP H CE2 1 ATOM 6187 C CE3 . TRP C 3 47 ? -159.390 -171.982 227.653 1.00 68.01 ? 47 TRP H CE3 1 ATOM 6188 C CZ2 . TRP C 3 47 ? -160.366 -169.356 227.246 1.00 68.63 ? 47 TRP H CZ2 1 ATOM 6189 C CZ3 . TRP C 3 47 ? -160.258 -171.681 226.608 1.00 72.65 ? 47 TRP H CZ3 1 ATOM 6190 C CH2 . TRP C 3 47 ? -160.740 -170.380 226.420 1.00 68.41 ? 47 TRP H CH2 1 ATOM 6191 N N . VAL C 3 48 ? -160.422 -172.209 231.455 1.00 72.33 ? 48 VAL H N 1 ATOM 6192 C CA . VAL C 3 48 ? -161.836 -172.520 231.339 1.00 70.02 ? 48 VAL H CA 1 ATOM 6193 C C . VAL C 3 48 ? -162.536 -171.674 230.296 1.00 69.41 ? 48 VAL H C 1 ATOM 6194 O O . VAL C 3 48 ? -163.155 -172.201 229.364 1.00 74.16 ? 48 VAL H O 1 ATOM 6195 C CB . VAL C 3 48 ? -162.546 -172.320 232.682 1.00 66.98 ? 48 VAL H CB 1 ATOM 6196 C CG1 . VAL C 3 48 ? -164.015 -172.645 232.545 1.00 71.04 ? 48 VAL H CG1 1 ATOM 6197 C CG2 . VAL C 3 48 ? -161.907 -173.191 233.739 1.00 65.91 ? 48 VAL H CG2 1 ATOM 6198 N N . ALA C 3 49 ? -162.450 -170.359 230.465 1.00 68.84 ? 49 ALA H N 1 ATOM 6199 C CA . ALA C 3 49 ? -163.092 -169.440 229.537 1.00 69.81 ? 49 ALA H CA 1 ATOM 6200 C C . ALA C 3 49 ? -162.483 -168.050 229.631 1.00 69.06 ? 49 ALA H C 1 ATOM 6201 O O . ALA C 3 49 ? -161.962 -167.659 230.682 1.00 70.39 ? 49 ALA H O 1 ATOM 6202 C CB . ALA C 3 49 ? -164.590 -169.380 229.796 1.00 69.33 ? 49 ALA H CB 1 ATOM 6203 N N . GLU C 3 50 ? -162.547 -167.309 228.526 1.00 70.93 ? 50 GLU H N 1 ATOM 6204 C CA . GLU C 3 50 ? -162.073 -165.929 228.490 1.00 69.81 ? 50 GLU H CA 1 ATOM 6205 C C . GLU C 3 50 ? -163.167 -165.008 227.975 1.00 74.14 ? 50 GLU H C 1 ATOM 6206 O O . GLU C 3 50 ? -163.906 -165.363 227.050 1.00 72.33 ? 50 GLU H O 1 ATOM 6207 C CB . GLU C 3 50 ? -160.838 -165.794 227.606 1.00 68.37 ? 50 GLU H CB 1 ATOM 6208 C CG . GLU C 3 50 ? -160.359 -164.356 227.446 1.00 74.39 ? 50 GLU H CG 1 ATOM 6209 C CD . GLU C 3 50 ? -159.265 -164.191 226.408 1.00 75.15 ? 50 GLU H CD 1 ATOM 6210 O OE1 . GLU C 3 50 ? -159.493 -164.533 225.232 1.00 75.91 ? 50 GLU H OE1 1 ATOM 6211 O OE2 . GLU C 3 50 ? -158.176 -163.710 226.782 1.00 78.50 ? 50 GLU H OE2 1 ATOM 6212 N N . ILE C 3 51 ? -163.272 -163.828 228.578 1.00 74.33 ? 51 ILE H N 1 ATOM 6213 C CA . ILE C 3 51 ? -164.214 -162.814 228.119 1.00 73.74 ? 51 ILE H CA 1 ATOM 6214 C C . ILE C 3 51 ? -163.470 -161.518 227.834 1.00 76.07 ? 51 ILE H C 1 ATOM 6215 O O . ILE C 3 51 ? -162.539 -161.162 228.556 1.00 75.27 ? 51 ILE H O 1 ATOM 6216 C CB . ILE C 3 51 ? -165.319 -162.548 229.146 1.00 76.08 ? 51 ILE H CB 1 ATOM 6217 C CG1 . ILE C 3 51 ? -166.325 -161.527 228.597 1.00 81.94 ? 51 ILE H CG1 1 ATOM 6218 C CG2 . ILE C 3 51 ? -164.724 -162.075 230.470 1.00 71.07 ? 51 ILE H CG2 1 ATOM 6219 C CD1 . ILE C 3 51 ? -167.678 -161.540 229.298 1.00 77.83 ? 51 ILE H CD1 1 ATOM 6220 N N . SER C 3 52 ? -163.903 -160.822 226.783 1.00 79.81 ? 52 SER H N 1 ATOM 6221 C CA . SER C 3 52 ? -163.290 -159.574 226.336 1.00 73.66 ? 52 SER H CA 1 ATOM 6222 C C . SER C 3 52 ? -163.463 -158.475 227.345 1.00 79.36 ? 52 SER H C 1 ATOM 6223 O O . SER C 3 52 ? -164.272 -158.571 228.276 1.00 82.61 ? 52 SER H O 1 ATOM 6224 C CB . SER C 3 52 ? -163.895 -159.103 225.026 1.00 77.35 ? 52 SER H CB 1 ATOM 6225 O OG . SER C 3 52 ? -164.007 -160.162 224.106 1.00 80.68 ? 52 SER H OG 1 ATOM 6226 N N . SER C 3 53 ? -162.685 -157.423 227.165 1.00 82.52 ? 53 SER H N 1 ATOM 6227 C CA . SER C 3 53 ? -162.806 -156.263 228.023 1.00 82.21 ? 53 SER H CA 1 ATOM 6228 C C . SER C 3 53 ? -164.215 -155.703 227.929 1.00 84.21 ? 53 SER H C 1 ATOM 6229 O O . SER C 3 53 ? -164.800 -155.297 228.929 1.00 82.96 ? 53 SER H O 1 ATOM 6230 C CB . SER C 3 53 ? -161.773 -155.215 227.611 1.00 83.42 ? 53 SER H CB 1 ATOM 6231 O OG . SER C 3 53 ? -161.648 -155.196 226.188 1.00 90.00 ? 53 SER H OG 1 ATOM 6232 N N . GLY C 3 54 ? -164.769 -155.720 226.721 1.00 84.70 ? 54 GLY H N 1 ATOM 6233 C CA . GLY C 3 54 ? -166.125 -155.254 226.496 1.00 76.25 ? 54 GLY H CA 1 ATOM 6234 C C . GLY C 3 54 ? -167.111 -156.394 226.429 1.00 80.13 ? 54 GLY H C 1 ATOM 6235 O O . GLY C 3 54 ? -168.281 -156.197 226.119 1.00 87.19 ? 54 GLY H O 1 ATOM 6236 N N . GLY C 3 55 ? -166.623 -157.606 226.656 1.00 84.09 ? 55 GLY H N 1 ATOM 6237 C CA . GLY C 3 55 ? -167.488 -158.762 226.779 1.00 78.17 ? 55 GLY H CA 1 ATOM 6238 C C . GLY C 3 55 ? -168.006 -159.310 225.466 1.00 82.88 ? 55 GLY H C 1 ATOM 6239 O O . GLY C 3 55 ? -168.848 -160.215 225.452 1.00 84.10 ? 55 GLY H O 1 ATOM 6240 N N . ARG C 3 56 ? -167.508 -158.774 224.356 1.00 84.15 ? 56 ARG H N 1 ATOM 6241 C CA . ARG C 3 56 ? -168.009 -159.182 223.051 1.00 84.48 ? 56 ARG H CA 1 ATOM 6242 C C . ARG C 3 56 ? -167.293 -160.371 222.401 1.00 81.15 ? 56 ARG H C 1 ATOM 6243 O O . ARG C 3 56 ? -167.775 -160.897 221.398 1.00 85.71 ? 56 ARG H O 1 ATOM 6244 C CB . ARG C 3 56 ? -167.991 -157.984 222.108 1.00 86.20 ? 56 ARG H CB 1 ATOM 6245 C CG . ARG C 3 56 ? -169.163 -157.035 222.354 1.00 96.55 ? 56 ARG H CG 1 ATOM 6246 C CD . ARG C 3 56 ? -169.137 -155.848 221.410 1.00 101.19 ? 56 ARG H CD 1 ATOM 6247 N NE . ARG C 3 56 ? -167.791 -155.308 221.304 1.00 100.11 ? 56 ARG H NE 1 ATOM 6248 C CZ . ARG C 3 56 ? -167.158 -155.102 220.155 1.00 102.96 ? 56 ARG H CZ 1 ATOM 6249 N NH1 . ARG C 3 56 ? -167.747 -155.372 218.994 1.00 100.74 ? 56 ARG H NH1 1 ATOM 6250 N NH2 . ARG C 3 56 ? -165.928 -154.618 220.172 1.00 99.77 ? 56 ARG H NH2 1 ATOM 6251 N N . TYR C 3 57 ? -166.167 -160.811 222.958 1.00 78.98 ? 57 TYR H N 1 ATOM 6252 C CA . TYR C 3 57 ? -165.498 -162.011 222.439 1.00 77.68 ? 57 TYR H CA 1 ATOM 6253 C C . TYR C 3 57 ? -165.295 -163.037 223.559 1.00 77.48 ? 57 TYR H C 1 ATOM 6254 O O . TYR C 3 57 ? -164.568 -162.793 224.530 1.00 76.56 ? 57 TYR H O 1 ATOM 6255 C CB . TYR C 3 57 ? -164.157 -161.661 221.768 1.00 75.54 ? 57 TYR H CB 1 ATOM 6256 C CG . TYR C 3 57 ? -164.270 -160.698 220.602 1.00 79.16 ? 57 TYR H CG 1 ATOM 6257 C CD1 . TYR C 3 57 ? -164.412 -161.162 219.298 1.00 82.31 ? 57 TYR H CD1 1 ATOM 6258 C CD2 . TYR C 3 57 ? -164.247 -159.324 220.808 1.00 81.76 ? 57 TYR H CD2 1 ATOM 6259 C CE1 . TYR C 3 57 ? -164.528 -160.285 218.234 1.00 84.79 ? 57 TYR H CE1 1 ATOM 6260 C CE2 . TYR C 3 57 ? -164.365 -158.437 219.754 1.00 81.77 ? 57 TYR H CE2 1 ATOM 6261 C CZ . TYR C 3 57 ? -164.502 -158.920 218.470 1.00 86.92 ? 57 TYR H CZ 1 ATOM 6262 O OH . TYR C 3 57 ? -164.611 -158.034 217.420 1.00 89.42 ? 57 TYR H OH 1 ATOM 6263 N N . ILE C 3 58 ? -165.956 -164.182 223.415 1.00 71.88 ? 58 ILE H N 1 ATOM 6264 C CA . ILE C 3 58 ? -165.966 -165.203 224.450 1.00 72.61 ? 58 ILE H CA 1 ATOM 6265 C C . ILE C 3 58 ? -165.376 -166.505 223.917 1.00 76.72 ? 58 ILE H C 1 ATOM 6266 O O . ILE C 3 58 ? -165.814 -167.008 222.878 1.00 75.42 ? 58 ILE H O 1 ATOM 6267 C CB . ILE C 3 58 ? -167.408 -165.482 224.965 1.00 69.30 ? 58 ILE H CB 1 ATOM 6268 C CG1 . ILE C 3 58 ? -168.089 -164.204 225.440 1.00 66.51 ? 58 ILE H CG1 1 ATOM 6269 C CG2 . ILE C 3 58 ? -167.378 -166.469 226.098 1.00 75.00 ? 58 ILE H CG2 1 ATOM 6270 C CD1 . ILE C 3 58 ? -167.532 -163.697 226.731 1.00 79.09 ? 58 ILE H CD1 1 ATOM 6271 N N . TYR C 3 59 ? -164.392 -167.060 224.622 1.00 72.72 ? 59 TYR H N 1 ATOM 6272 C CA . TYR C 3 59 ? -163.875 -168.376 224.261 1.00 71.80 ? 59 TYR H CA 1 ATOM 6273 C C . TYR C 3 59 ? -164.051 -169.367 225.421 1.00 74.14 ? 59 TYR H C 1 ATOM 6274 O O . TYR C 3 59 ? -163.917 -168.996 226.586 1.00 74.75 ? 59 TYR H O 1 ATOM 6275 C CB . TYR C 3 59 ? -162.400 -168.287 223.861 1.00 72.81 ? 59 TYR H CB 1 ATOM 6276 C CG . TYR C 3 59 ? -162.117 -167.347 222.703 1.00 76.82 ? 59 TYR H CG 1 ATOM 6277 C CD1 . TYR C 3 59 ? -162.074 -167.819 221.392 1.00 71.80 ? 59 TYR H CD1 1 ATOM 6278 C CD2 . TYR C 3 59 ? -161.882 -165.987 222.919 1.00 71.54 ? 59 TYR H CD2 1 ATOM 6279 C CE1 . TYR C 3 59 ? -161.812 -166.965 220.331 1.00 75.98 ? 59 TYR H CE1 1 ATOM 6280 C CE2 . TYR C 3 59 ? -161.614 -165.130 221.863 1.00 72.18 ? 59 TYR H CE2 1 ATOM 6281 C CZ . TYR C 3 59 ? -161.580 -165.619 220.567 1.00 79.53 ? 59 TYR H CZ 1 ATOM 6282 O OH . TYR C 3 59 ? -161.317 -164.769 219.499 1.00 82.38 ? 59 TYR H OH 1 ATOM 6283 N N . TYR C 3 60 ? -164.341 -170.625 225.098 1.00 69.38 ? 60 TYR H N 1 ATOM 6284 C CA . TYR C 3 60 ? -164.507 -171.670 226.105 1.00 70.90 ? 60 TYR H CA 1 ATOM 6285 C C . TYR C 3 60 ? -163.613 -172.863 225.810 1.00 73.91 ? 60 TYR H C 1 ATOM 6286 O O . TYR C 3 60 ? -163.386 -173.191 224.650 1.00 78.29 ? 60 TYR H O 1 ATOM 6287 C CB . TYR C 3 60 ? -165.966 -172.147 226.165 1.00 69.89 ? 60 TYR H CB 1 ATOM 6288 C CG . TYR C 3 60 ? -166.969 -171.104 226.593 1.00 72.09 ? 60 TYR H CG 1 ATOM 6289 C CD1 . TYR C 3 60 ? -167.020 -170.647 227.903 1.00 72.38 ? 60 TYR H CD1 1 ATOM 6290 C CD2 . TYR C 3 60 ? -167.880 -170.581 225.693 1.00 75.52 ? 60 TYR H CD2 1 ATOM 6291 C CE1 . TYR C 3 60 ? -167.943 -169.688 228.291 1.00 70.44 ? 60 TYR H CE1 1 ATOM 6292 C CE2 . TYR C 3 60 ? -168.804 -169.622 226.083 1.00 71.16 ? 60 TYR H CE2 1 ATOM 6293 C CZ . TYR C 3 60 ? -168.835 -169.188 227.377 1.00 68.70 ? 60 TYR H CZ 1 ATOM 6294 O OH . TYR C 3 60 ? -169.758 -168.232 227.742 1.00 78.06 ? 60 TYR H OH 1 ATOM 6295 N N . SER C 3 61 ? -163.131 -173.538 226.849 1.00 72.35 ? 61 SER H N 1 ATOM 6296 C CA . SER C 3 61 ? -162.471 -174.824 226.630 1.00 77.83 ? 61 SER H CA 1 ATOM 6297 C C . SER C 3 61 ? -163.523 -175.834 226.177 1.00 80.29 ? 61 SER H C 1 ATOM 6298 O O . SER C 3 61 ? -164.704 -175.668 226.460 1.00 78.54 ? 61 SER H O 1 ATOM 6299 C CB . SER C 3 61 ? -161.758 -175.308 227.887 1.00 78.38 ? 61 SER H CB 1 ATOM 6300 O OG . SER C 3 61 ? -162.595 -176.120 228.686 1.00 84.23 ? 61 SER H OG 1 ATOM 6301 N N . ASP C 3 62 ? -163.128 -176.857 225.435 1.00 88.29 ? 62 ASP H N 1 ATOM 6302 C CA . ASP C 3 62 ? -164.129 -177.819 224.971 1.00 88.83 ? 62 ASP H CA 1 ATOM 6303 C C . ASP C 3 62 ? -164.751 -178.562 226.150 1.00 86.54 ? 62 ASP H C 1 ATOM 6304 O O . ASP C 3 62 ? -165.852 -179.085 226.038 1.00 90.29 ? 62 ASP H O 1 ATOM 6305 C CB . ASP C 3 62 ? -163.525 -178.824 223.988 1.00 92.47 ? 62 ASP H CB 1 ATOM 6306 C CG . ASP C 3 62 ? -163.136 -178.192 222.661 1.00 106.64 ? 62 ASP H CG 1 ATOM 6307 O OD1 . ASP C 3 62 ? -163.551 -177.040 222.390 1.00 104.39 ? 62 ASP H OD1 1 ATOM 6308 O OD2 . ASP C 3 62 ? -162.425 -178.861 221.878 1.00 118.31 ? 62 ASP H OD2 1 ATOM 6309 N N . THR C 3 63 ? -164.035 -178.611 227.271 1.00 83.33 ? 63 THR H N 1 ATOM 6310 C CA . THR C 3 63 ? -164.483 -179.329 228.461 1.00 81.09 ? 63 THR H CA 1 ATOM 6311 C C . THR C 3 63 ? -165.773 -178.770 229.067 1.00 85.68 ? 63 THR H C 1 ATOM 6312 O O . THR C 3 63 ? -166.587 -179.518 229.604 1.00 89.45 ? 63 THR H O 1 ATOM 6313 C CB . THR C 3 63 ? -163.409 -179.308 229.573 1.00 85.60 ? 63 THR H CB 1 ATOM 6314 O OG1 . THR C 3 63 ? -162.158 -179.794 229.073 1.00 89.33 ? 63 THR H OG1 1 ATOM 6315 C CG2 . THR C 3 63 ? -163.844 -180.171 230.731 1.00 95.61 ? 63 THR H CG2 1 ATOM 6316 N N . VAL C 3 64 ? -165.953 -177.454 228.985 1.00 79.90 ? 64 VAL H N 1 ATOM 6317 C CA . VAL C 3 64 ? -167.071 -176.803 229.642 1.00 76.88 ? 64 VAL H CA 1 ATOM 6318 C C . VAL C 3 64 ? -168.044 -176.116 228.679 1.00 79.63 ? 64 VAL H C 1 ATOM 6319 O O . VAL C 3 64 ? -169.018 -175.491 229.110 1.00 82.32 ? 64 VAL H O 1 ATOM 6320 C CB . VAL C 3 64 ? -166.580 -175.741 230.649 1.00 78.12 ? 64 VAL H CB 1 ATOM 6321 C CG1 . VAL C 3 64 ? -165.628 -176.357 231.653 1.00 77.87 ? 64 VAL H CG1 1 ATOM 6322 C CG2 . VAL C 3 64 ? -165.929 -174.580 229.916 1.00 72.87 ? 64 VAL H CG2 1 ATOM 6323 N N . THR C 3 65 ? -167.787 -176.193 227.383 1.00 79.51 ? 65 THR H N 1 ATOM 6324 C CA . THR C 3 65 ? -168.604 -175.431 226.443 1.00 80.93 ? 65 THR H CA 1 ATOM 6325 C C . THR C 3 65 ? -170.057 -175.935 226.386 1.00 83.90 ? 65 THR H C 1 ATOM 6326 O O . THR C 3 65 ? -170.316 -177.135 226.367 1.00 79.91 ? 65 THR H O 1 ATOM 6327 C CB . THR C 3 65 ? -167.980 -175.452 225.052 1.00 76.60 ? 65 THR H CB 1 ATOM 6328 O OG1 . THR C 3 65 ? -168.829 -174.744 224.147 1.00 82.14 ? 65 THR H OG1 1 ATOM 6329 C CG2 . THR C 3 65 ? -167.784 -176.880 224.580 1.00 75.28 ? 65 THR H CG2 1 ATOM 6330 N N . GLY C 3 66 ? -171.005 -175.005 226.385 1.00 83.70 ? 66 GLY H N 1 ATOM 6331 C CA . GLY C 3 66 ? -172.412 -175.365 226.397 1.00 82.65 ? 66 GLY H CA 1 ATOM 6332 C C . GLY C 3 66 ? -172.943 -175.676 227.785 1.00 83.33 ? 66 GLY H C 1 ATOM 6333 O O . GLY C 3 66 ? -174.154 -175.842 227.972 1.00 88.24 ? 66 GLY H O 1 ATOM 6334 N N . ARG C 3 67 ? -172.043 -175.714 228.767 1.00 81.92 ? 67 ARG H N 1 ATOM 6335 C CA . ARG C 3 67 ? -172.429 -175.899 230.164 1.00 77.92 ? 67 ARG H CA 1 ATOM 6336 C C . ARG C 3 67 ? -172.106 -174.659 230.998 1.00 80.39 ? 67 ARG H C 1 ATOM 6337 O O . ARG C 3 67 ? -172.915 -174.231 231.824 1.00 82.93 ? 67 ARG H O 1 ATOM 6338 C CB . ARG C 3 67 ? -171.737 -177.113 230.765 1.00 78.61 ? 67 ARG H CB 1 ATOM 6339 C CG . ARG C 3 67 ? -172.220 -178.438 230.227 1.00 76.02 ? 67 ARG H CG 1 ATOM 6340 C CD . ARG C 3 67 ? -171.588 -179.572 230.990 1.00 81.95 ? 67 ARG H CD 1 ATOM 6341 N NE . ARG C 3 67 ? -170.129 -179.480 231.065 1.00 85.01 ? 67 ARG H NE 1 ATOM 6342 C CZ . ARG C 3 67 ? -169.444 -179.489 232.203 1.00 83.28 ? 67 ARG H CZ 1 ATOM 6343 N NH1 . ARG C 3 67 ? -170.088 -179.579 233.355 1.00 84.67 ? 67 ARG H NH1 1 ATOM 6344 N NH2 . ARG C 3 67 ? -168.122 -179.412 232.191 1.00 84.08 ? 67 ARG H NH2 1 ATOM 6345 N N . PHE C 3 68 ? -170.914 -174.097 230.799 1.00 82.15 ? 68 PHE H N 1 ATOM 6346 C CA . PHE C 3 68 ? -170.517 -172.872 231.494 1.00 79.86 ? 68 PHE H CA 1 ATOM 6347 C C . PHE C 3 68 ? -170.877 -171.654 230.671 1.00 74.50 ? 68 PHE H C 1 ATOM 6348 O O . PHE C 3 68 ? -170.965 -171.734 229.448 1.00 76.79 ? 68 PHE H O 1 ATOM 6349 C CB . PHE C 3 68 ? -169.013 -172.851 231.797 1.00 77.52 ? 68 PHE H CB 1 ATOM 6350 C CG . PHE C 3 68 ? -168.586 -173.809 232.872 1.00 76.94 ? 68 PHE H CG 1 ATOM 6351 C CD1 . PHE C 3 68 ? -169.435 -174.807 233.313 1.00 79.02 ? 68 PHE H CD1 1 ATOM 6352 C CD2 . PHE C 3 68 ? -167.330 -173.702 233.444 1.00 77.99 ? 68 PHE H CD2 1 ATOM 6353 C CE1 . PHE C 3 68 ? -169.043 -175.682 234.297 1.00 79.23 ? 68 PHE H CE1 1 ATOM 6354 C CE2 . PHE C 3 68 ? -166.926 -174.579 234.426 1.00 78.10 ? 68 PHE H CE2 1 ATOM 6355 C CZ . PHE C 3 68 ? -167.791 -175.573 234.854 1.00 79.94 ? 68 PHE H CZ 1 ATOM 6356 N N . THR C 3 69 ? -171.053 -170.523 231.343 1.00 72.93 ? 69 THR H N 1 ATOM 6357 C CA . THR C 3 69 ? -171.295 -169.260 230.665 1.00 75.47 ? 69 THR H CA 1 ATOM 6358 C C . THR C 3 69 ? -170.575 -168.146 231.398 1.00 79.77 ? 69 THR H C 1 ATOM 6359 O O . THR C 3 69 ? -170.905 -167.834 232.550 1.00 81.20 ? 69 THR H O 1 ATOM 6360 C CB . THR C 3 69 ? -172.798 -168.913 230.586 1.00 81.69 ? 69 THR H CB 1 ATOM 6361 O OG1 . THR C 3 69 ? -173.449 -169.778 229.652 1.00 82.19 ? 69 THR H OG1 1 ATOM 6362 C CG2 . THR C 3 69 ? -172.993 -167.473 230.140 1.00 76.04 ? 69 THR H CG2 1 ATOM 6363 N N . ILE C 3 70 ? -169.591 -167.542 230.737 1.00 76.53 ? 70 ILE H N 1 ATOM 6364 C CA . ILE C 3 70 ? -168.848 -166.443 231.348 1.00 77.80 ? 70 ILE H CA 1 ATOM 6365 C C . ILE C 3 70 ? -169.524 -165.100 231.066 1.00 77.69 ? 70 ILE H C 1 ATOM 6366 O O . ILE C 3 70 ? -170.046 -164.868 229.975 1.00 75.74 ? 70 ILE H O 1 ATOM 6367 C CB . ILE C 3 70 ? -167.395 -166.418 230.859 1.00 75.37 ? 70 ILE H CB 1 ATOM 6368 C CG1 . ILE C 3 70 ? -166.571 -165.440 231.702 1.00 71.44 ? 70 ILE H CG1 1 ATOM 6369 C CG2 . ILE C 3 70 ? -167.348 -166.123 229.367 1.00 73.15 ? 70 ILE H CG2 1 ATOM 6370 C CD1 . ILE C 3 70 ? -165.084 -165.545 231.459 1.00 71.41 ? 70 ILE H CD1 1 ATOM 6371 N N . SER C 3 71 ? -169.522 -164.218 232.058 1.00 75.18 ? 71 SER H N 1 ATOM 6372 C CA . SER C 3 71 ? -170.311 -162.992 231.985 1.00 73.84 ? 71 SER H CA 1 ATOM 6373 C C . SER C 3 71 ? -169.526 -161.922 232.668 1.00 77.84 ? 71 SER H C 1 ATOM 6374 O O . SER C 3 71 ? -168.579 -162.192 233.400 1.00 80.74 ? 71 SER H O 1 ATOM 6375 C CB . SER C 3 71 ? -171.694 -163.106 232.660 1.00 77.46 ? 71 SER H CB 1 ATOM 6376 O OG . SER C 3 71 ? -172.275 -164.401 232.537 1.00 99.31 ? 71 SER H OG 1 ATOM 6377 N N . ARG C 3 72 ? -169.950 -160.695 232.445 1.00 83.32 ? 72 ARG H N 1 ATOM 6378 C CA . ARG C 3 72 ? -169.141 -159.565 232.796 1.00 78.75 ? 72 ARG H CA 1 ATOM 6379 C C . ARG C 3 72 ? -170.059 -158.417 233.173 1.00 79.89 ? 72 ARG H C 1 ATOM 6380 O O . ARG C 3 72 ? -170.966 -158.078 232.418 1.00 85.13 ? 72 ARG H O 1 ATOM 6381 C CB . ARG C 3 72 ? -168.248 -159.207 231.610 1.00 76.80 ? 72 ARG H CB 1 ATOM 6382 C CG . ARG C 3 72 ? -167.030 -158.477 231.990 1.00 77.26 ? 72 ARG H CG 1 ATOM 6383 C CD . ARG C 3 72 ? -166.282 -157.979 230.798 1.00 74.83 ? 72 ARG H CD 1 ATOM 6384 N NE . ARG C 3 72 ? -165.300 -157.018 231.279 1.00 83.59 ? 72 ARG H NE 1 ATOM 6385 C CZ . ARG C 3 72 ? -164.050 -157.323 231.592 1.00 76.12 ? 72 ARG H CZ 1 ATOM 6386 N NH1 . ARG C 3 72 ? -163.618 -158.558 231.432 1.00 80.25 ? 72 ARG H NH1 1 ATOM 6387 N NH2 . ARG C 3 72 ? -163.230 -156.389 232.040 1.00 79.57 ? 72 ARG H NH2 1 ATOM 6388 N N . ASP C 3 73 ? -169.838 -157.832 234.342 1.00 79.38 ? 73 ASP H N 1 ATOM 6389 C CA . ASP C 3 73 ? -170.564 -156.640 234.745 1.00 79.65 ? 73 ASP H CA 1 ATOM 6390 C C . ASP C 3 73 ? -169.599 -155.479 234.899 1.00 85.11 ? 73 ASP H C 1 ATOM 6391 O O . ASP C 3 73 ? -169.022 -155.270 235.971 1.00 81.93 ? 73 ASP H O 1 ATOM 6392 C CB . ASP C 3 73 ? -171.321 -156.878 236.047 1.00 90.47 ? 73 ASP H CB 1 ATOM 6393 C CG . ASP C 3 73 ? -172.129 -155.665 236.481 1.00 95.91 ? 73 ASP H CG 1 ATOM 6394 O OD1 . ASP C 3 73 ? -172.253 -154.701 235.692 1.00 97.45 ? 73 ASP H OD1 1 ATOM 6395 O OD2 . ASP C 3 73 ? -172.649 -155.685 237.613 1.00 98.82 ? 73 ASP H OD2 1 ATOM 6396 N N . ASN C 3 74 ? -169.432 -154.727 233.817 1.00 84.66 ? 74 ASN H N 1 ATOM 6397 C CA . ASN C 3 74 ? -168.454 -153.654 233.790 1.00 84.13 ? 74 ASN H CA 1 ATOM 6398 C C . ASN C 3 74 ? -168.857 -152.439 234.619 1.00 88.34 ? 74 ASN H C 1 ATOM 6399 O O . ASN C 3 74 ? -168.023 -151.588 234.931 1.00 90.25 ? 74 ASN H O 1 ATOM 6400 C CB . ASN C 3 74 ? -168.180 -153.230 232.350 1.00 84.92 ? 74 ASN H CB 1 ATOM 6401 C CG . ASN C 3 74 ? -167.088 -154.059 231.696 1.00 82.62 ? 74 ASN H CG 1 ATOM 6402 O OD1 . ASN C 3 74 ? -165.922 -153.966 232.071 1.00 88.39 ? 74 ASN H OD1 1 ATOM 6403 N ND2 . ASN C 3 74 ? -167.457 -154.861 230.708 1.00 79.15 ? 74 ASN H ND2 1 ATOM 6404 N N . ALA C 3 75 ? -170.135 -152.344 234.967 1.00 94.74 ? 75 ALA H N 1 ATOM 6405 C CA . ALA C 3 75 ? -170.583 -151.249 235.818 1.00 92.20 ? 75 ALA H CA 1 ATOM 6406 C C . ALA C 3 75 ? -170.182 -151.489 237.266 1.00 89.18 ? 75 ALA H C 1 ATOM 6407 O O . ALA C 3 75 ? -169.645 -150.595 237.918 1.00 84.31 ? 75 ALA H O 1 ATOM 6408 C CB . ALA C 3 75 ? -172.078 -151.073 235.706 1.00 90.39 ? 75 ALA H CB 1 ATOM 6409 N N . ARG C 3 76 ? -170.422 -152.710 237.748 1.00 93.34 ? 76 ARG H N 1 ATOM 6410 C CA . ARG C 3 76 ? -170.194 -153.063 239.152 1.00 91.45 ? 76 ARG H CA 1 ATOM 6411 C C . ARG C 3 76 ? -168.851 -153.745 239.398 1.00 92.74 ? 76 ARG H C 1 ATOM 6412 O O . ARG C 3 76 ? -168.562 -154.120 240.534 1.00 90.80 ? 76 ARG H O 1 ATOM 6413 C CB . ARG C 3 76 ? -171.324 -153.966 239.671 1.00 90.87 ? 76 ARG H CB 1 ATOM 6414 C CG . ARG C 3 76 ? -172.666 -153.244 239.816 1.00 98.52 ? 76 ARG H CG 1 ATOM 6415 C CD . ARG C 3 76 ? -173.796 -154.151 240.305 1.00 95.84 ? 76 ARG H CD 1 ATOM 6416 N NE . ARG C 3 76 ? -174.181 -155.150 239.308 1.00 116.60 ? 76 ARG H NE 1 ATOM 6417 C CZ . ARG C 3 76 ? -175.337 -155.821 239.304 1.00 116.08 ? 76 ARG H CZ 1 ATOM 6418 N NH1 . ARG C 3 76 ? -176.253 -155.599 240.246 1.00 106.43 ? 76 ARG H NH1 1 ATOM 6419 N NH2 . ARG C 3 76 ? -175.580 -156.716 238.346 1.00 112.90 ? 76 ARG H NH2 1 ATOM 6420 N N . ASN C 3 77 ? -168.045 -153.908 238.341 1.00 92.47 ? 77 ASN H N 1 ATOM 6421 C CA . ASN C 3 77 ? -166.742 -154.589 238.417 1.00 82.84 ? 77 ASN H CA 1 ATOM 6422 C C . ASN C 3 77 ? -166.759 -156.032 238.903 1.00 79.95 ? 77 ASN H C 1 ATOM 6423 O O . ASN C 3 77 ? -165.972 -156.397 239.770 1.00 82.37 ? 77 ASN H O 1 ATOM 6424 C CB . ASN C 3 77 ? -165.811 -153.802 239.326 1.00 83.83 ? 77 ASN H CB 1 ATOM 6425 C CG . ASN C 3 77 ? -165.330 -152.531 238.685 1.00 94.08 ? 77 ASN H CG 1 ATOM 6426 O OD1 . ASN C 3 77 ? -165.957 -152.033 237.746 1.00 95.61 ? 77 ASN H OD1 1 ATOM 6427 N ND2 . ASN C 3 77 ? -164.206 -151.994 239.178 1.00 91.39 ? 77 ASN H ND2 1 ATOM 6428 N N . ILE C 3 78 ? -167.652 -156.846 238.352 1.00 81.93 ? 78 ILE H N 1 ATOM 6429 C CA . ILE C 3 78 ? -167.792 -158.235 238.785 1.00 84.21 ? 78 ILE H CA 1 ATOM 6430 C C . ILE C 3 78 ? -167.723 -159.195 237.602 1.00 85.22 ? 78 ILE H C 1 ATOM 6431 O O . ILE C 3 78 ? -168.504 -159.082 236.660 1.00 87.00 ? 78 ILE H O 1 ATOM 6432 C CB . ILE C 3 78 ? -169.146 -158.481 239.534 1.00 87.09 ? 78 ILE H CB 1 ATOM 6433 C CG1 . ILE C 3 78 ? -169.304 -157.556 240.748 1.00 86.78 ? 78 ILE H CG1 1 ATOM 6434 C CG2 . ILE C 3 78 ? -169.291 -159.945 239.938 1.00 75.60 ? 78 ILE H CG2 1 ATOM 6435 C CD1 . ILE C 3 78 ? -168.417 -157.910 241.920 1.00 87.38 ? 78 ILE H CD1 1 ATOM 6436 N N . LEU C 3 79 ? -166.782 -160.132 237.644 1.00 85.00 ? 79 LEU H N 1 ATOM 6437 C CA . LEU C 3 79 ? -166.743 -161.218 236.672 1.00 79.11 ? 79 LEU H CA 1 ATOM 6438 C C . LEU C 3 79 ? -167.618 -162.395 237.117 1.00 78.12 ? 79 LEU H C 1 ATOM 6439 O O . LEU C 3 79 ? -167.772 -162.641 238.317 1.00 79.35 ? 79 LEU H O 1 ATOM 6440 C CB . LEU C 3 79 ? -165.309 -161.674 236.465 1.00 76.93 ? 79 LEU H CB 1 ATOM 6441 C CG . LEU C 3 79 ? -165.181 -162.722 235.370 1.00 80.02 ? 79 LEU H CG 1 ATOM 6442 C CD1 . LEU C 3 79 ? -165.294 -162.070 233.984 1.00 80.99 ? 79 LEU H CD1 1 ATOM 6443 C CD2 . LEU C 3 79 ? -163.877 -163.507 235.535 1.00 76.31 ? 79 LEU H CD2 1 ATOM 6444 N N . HIS C 3 80 ? -168.155 -163.143 236.160 1.00 73.64 ? 80 HIS H N 1 ATOM 6445 C CA . HIS C 3 80 ? -169.080 -164.232 236.478 1.00 75.98 ? 80 HIS H CA 1 ATOM 6446 C C . HIS C 3 80 ? -168.820 -165.512 235.684 1.00 80.59 ? 80 HIS H C 1 ATOM 6447 O O . HIS C 3 80 ? -168.588 -165.479 234.473 1.00 84.21 ? 80 HIS H O 1 ATOM 6448 C CB . HIS C 3 80 ? -170.532 -163.806 236.207 1.00 79.95 ? 80 HIS H CB 1 ATOM 6449 C CG . HIS C 3 80 ? -171.033 -162.713 237.099 1.00 82.97 ? 80 HIS H CG 1 ATOM 6450 N ND1 . HIS C 3 80 ? -171.370 -162.926 238.419 1.00 81.77 ? 80 HIS H ND1 1 ATOM 6451 C CD2 . HIS C 3 80 ? -171.268 -161.400 236.856 1.00 86.10 ? 80 HIS H CD2 1 ATOM 6452 C CE1 . HIS C 3 80 ? -171.777 -161.789 238.956 1.00 85.23 ? 80 HIS H CE1 1 ATOM 6453 N NE2 . HIS C 3 80 ? -171.721 -160.847 238.031 1.00 88.41 ? 80 HIS H NE2 1 ATOM 6454 N N . LEU C 3 81 ? -168.900 -166.647 236.359 1.00 74.39 ? 81 LEU H N 1 ATOM 6455 C CA . LEU C 3 81 ? -168.929 -167.920 235.670 1.00 71.77 ? 81 LEU H CA 1 ATOM 6456 C C . LEU C 3 81 ? -170.209 -168.616 236.090 1.00 78.44 ? 81 LEU H C 1 ATOM 6457 O O . LEU C 3 81 ? -170.376 -168.951 237.256 1.00 78.99 ? 81 LEU H O 1 ATOM 6458 C CB . LEU C 3 81 ? -167.708 -168.771 236.011 1.00 74.02 ? 81 LEU H CB 1 ATOM 6459 C CG . LEU C 3 81 ? -167.647 -170.109 235.279 1.00 72.08 ? 81 LEU H CG 1 ATOM 6460 C CD1 . LEU C 3 81 ? -167.501 -169.846 233.808 1.00 73.60 ? 81 LEU H CD1 1 ATOM 6461 C CD2 . LEU C 3 81 ? -166.515 -170.974 235.790 1.00 68.88 ? 81 LEU H CD2 1 ATOM 6462 N N . GLU C 3 82 ? -171.133 -168.789 235.153 1.00 83.36 ? 82 GLU H N 1 ATOM 6463 C CA . GLU C 3 82 ? -172.390 -169.460 235.443 1.00 80.02 ? 82 GLU H CA 1 ATOM 6464 C C . GLU C 3 82 ? -172.332 -170.912 235.015 1.00 81.07 ? 82 GLU H C 1 ATOM 6465 O O . GLU C 3 82 ? -172.378 -171.216 233.822 1.00 85.92 ? 82 GLU H O 1 ATOM 6466 C CB . GLU C 3 82 ? -173.548 -168.748 234.749 1.00 86.76 ? 82 GLU H CB 1 ATOM 6467 C CG . GLU C 3 82 ? -174.041 -167.513 235.481 1.00 94.30 ? 82 GLU H CG 1 ATOM 6468 C CD . GLU C 3 82 ? -175.027 -166.696 234.659 1.00 110.29 ? 82 GLU H CD 1 ATOM 6469 O OE1 . GLU C 3 82 ? -175.252 -167.052 233.476 1.00 110.10 ? 82 GLU H OE1 1 ATOM 6470 O OE2 . GLU C 3 82 ? -175.573 -165.697 235.195 1.00 114.61 ? 82 GLU H OE2 1 ATOM 6471 N N . MET C 3 83 ? -172.200 -171.802 235.992 1.00 78.44 ? 83 MET H N 1 ATOM 6472 C CA . MET C 3 83 ? -172.095 -173.234 235.721 1.00 83.45 ? 83 MET H CA 1 ATOM 6473 C C . MET C 3 83 ? -173.430 -173.968 235.729 1.00 83.46 ? 83 MET H C 1 ATOM 6474 O O . MET C 3 83 ? -174.387 -173.537 236.371 1.00 87.88 ? 83 MET H O 1 ATOM 6475 C CB . MET C 3 83 ? -171.167 -173.882 236.730 1.00 87.00 ? 83 MET H CB 1 ATOM 6476 C CG . MET C 3 83 ? -169.757 -173.383 236.639 1.00 79.01 ? 83 MET H CG 1 ATOM 6477 S SD . MET C 3 83 ? -168.972 -173.587 238.223 1.00 81.60 ? 83 MET H SD 1 ATOM 6478 C CE . MET C 3 83 ? -167.384 -174.096 237.633 1.00 75.48 ? 83 MET H CE 1 ATOM 6479 N N . SER C 3 84 ? -173.487 -175.091 235.024 1.00 77.10 ? 84 SER H N 1 ATOM 6480 C CA . SER C 3 84 ? -174.699 -175.895 235.003 1.00 80.41 ? 84 SER H CA 1 ATOM 6481 C C . SER C 3 84 ? -174.390 -177.312 234.535 1.00 79.76 ? 84 SER H C 1 ATOM 6482 O O . SER C 3 84 ? -173.323 -177.550 233.989 1.00 82.38 ? 84 SER H O 1 ATOM 6483 C CB . SER C 3 84 ? -175.739 -175.265 234.108 1.00 76.69 ? 84 SER H CB 1 ATOM 6484 O OG . SER C 3 84 ? -175.377 -175.473 232.775 1.00 78.42 ? 84 SER H OG 1 ATOM 6485 N N . SER C 3 85 ? -175.347 -178.223 234.714 1.00 81.32 ? 85 SER H N 1 ATOM 6486 C CA . SER C 3 85 ? -175.102 -179.667 234.671 1.00 81.25 ? 85 SER H CA 1 ATOM 6487 C C . SER C 3 85 ? -173.658 -179.935 235.041 1.00 77.55 ? 85 SER H C 1 ATOM 6488 O O . SER C 3 85 ? -172.865 -180.380 234.217 1.00 80.69 ? 85 SER H O 1 ATOM 6489 C CB . SER C 3 85 ? -175.454 -180.282 233.308 1.00 87.74 ? 85 SER H CB 1 ATOM 6490 O OG . SER C 3 85 ? -174.819 -179.610 232.244 1.00 95.63 ? 85 SER H OG 1 ATOM 6491 N N . LEU C 3 86 ? -173.330 -179.611 236.286 1.00 78.70 ? 86 LEU H N 1 ATOM 6492 C CA . LEU C 3 86 ? -172.003 -179.829 236.837 1.00 78.82 ? 86 LEU H CA 1 ATOM 6493 C C . LEU C 3 86 ? -171.736 -181.312 236.967 1.00 79.13 ? 86 LEU H C 1 ATOM 6494 O O . LEU C 3 86 ? -172.662 -182.109 237.063 1.00 80.07 ? 86 LEU H O 1 ATOM 6495 C CB . LEU C 3 86 ? -171.858 -179.158 238.198 1.00 77.99 ? 86 LEU H CB 1 ATOM 6496 C CG . LEU C 3 86 ? -171.885 -177.639 238.140 1.00 75.64 ? 86 LEU H CG 1 ATOM 6497 C CD1 . LEU C 3 86 ? -171.814 -177.028 239.518 1.00 71.31 ? 86 LEU H CD1 1 ATOM 6498 C CD2 . LEU C 3 86 ? -170.711 -177.204 237.301 1.00 83.82 ? 86 LEU H CD2 1 ATOM 6499 N N . ARG C 3 87 ? -170.466 -181.684 236.949 1.00 86.41 ? 87 ARG H N 1 ATOM 6500 C CA . ARG C 3 87 ? -170.076 -183.074 237.124 1.00 82.02 ? 87 ARG H CA 1 ATOM 6501 C C . ARG C 3 87 ? -168.771 -183.118 237.916 1.00 78.44 ? 87 ARG H C 1 ATOM 6502 O O . ARG C 3 87 ? -168.072 -182.116 238.008 1.00 80.93 ? 87 ARG H O 1 ATOM 6503 C CB . ARG C 3 87 ? -169.922 -183.748 235.771 1.00 80.50 ? 87 ARG H CB 1 ATOM 6504 C CG . ARG C 3 87 ? -168.720 -183.241 235.049 1.00 90.68 ? 87 ARG H CG 1 ATOM 6505 C CD . ARG C 3 87 ? -168.481 -183.993 233.760 1.00 104.16 ? 87 ARG H CD 1 ATOM 6506 N NE . ARG C 3 87 ? -169.152 -183.370 232.621 1.00 107.01 ? 87 ARG H NE 1 ATOM 6507 C CZ . ARG C 3 87 ? -168.924 -183.718 231.360 1.00 108.63 ? 87 ARG H CZ 1 ATOM 6508 N NH1 . ARG C 3 87 ? -169.565 -183.108 230.372 1.00 101.86 ? 87 ARG H NH1 1 ATOM 6509 N NH2 . ARG C 3 87 ? -168.051 -184.684 231.096 1.00 119.15 ? 87 ARG H NH2 1 ATOM 6510 N N . SER C 3 88 ? -168.444 -184.271 238.486 1.00 81.10 ? 88 SER H N 1 ATOM 6511 C CA . SER C 3 88 ? -167.351 -184.353 239.449 1.00 82.12 ? 88 SER H CA 1 ATOM 6512 C C . SER C 3 88 ? -166.010 -183.941 238.839 1.00 81.93 ? 88 SER H C 1 ATOM 6513 O O . SER C 3 88 ? -165.111 -183.485 239.548 1.00 84.81 ? 88 SER H O 1 ATOM 6514 C CB . SER C 3 88 ? -167.259 -185.767 240.038 1.00 80.95 ? 88 SER H CB 1 ATOM 6515 O OG . SER C 3 88 ? -166.949 -186.721 239.040 1.00 87.11 ? 88 SER H OG 1 ATOM 6516 N N . GLU C 3 89 ? -165.882 -184.080 237.526 1.00 83.01 ? 89 GLU H N 1 ATOM 6517 C CA . GLU C 3 89 ? -164.676 -183.644 236.831 1.00 81.96 ? 89 GLU H CA 1 ATOM 6518 C C . GLU C 3 89 ? -164.482 -182.131 236.947 1.00 81.18 ? 89 GLU H C 1 ATOM 6519 O O . GLU C 3 89 ? -163.392 -181.624 236.727 1.00 82.76 ? 89 GLU H O 1 ATOM 6520 C CB . GLU C 3 89 ? -164.740 -184.046 235.361 1.00 90.89 ? 89 GLU H CB 1 ATOM 6521 C CG . GLU C 3 89 ? -165.038 -182.866 234.445 1.00 104.98 ? 89 GLU H CG 1 ATOM 6522 C CD . GLU C 3 89 ? -165.210 -183.265 232.983 1.00 114.15 ? 89 GLU H CD 1 ATOM 6523 O OE1 . GLU C 3 89 ? -165.402 -184.481 232.710 1.00 114.63 ? 89 GLU H OE1 1 ATOM 6524 O OE2 . GLU C 3 89 ? -165.168 -182.352 232.115 1.00 109.62 ? 89 GLU H OE2 1 ATOM 6525 N N . ASP C 3 90 ? -165.549 -181.406 237.270 1.00 84.71 ? 90 ASP H N 1 ATOM 6526 C CA . ASP C 3 90 ? -165.473 -179.948 237.434 1.00 81.77 ? 90 ASP H CA 1 ATOM 6527 C C . ASP C 3 90 ? -164.978 -179.510 238.816 1.00 74.30 ? 90 ASP H C 1 ATOM 6528 O O . ASP C 3 90 ? -164.805 -178.318 239.068 1.00 73.13 ? 90 ASP H O 1 ATOM 6529 C CB . ASP C 3 90 ? -166.838 -179.306 237.161 1.00 79.00 ? 90 ASP H CB 1 ATOM 6530 C CG . ASP C 3 90 ? -167.298 -179.511 235.730 1.00 84.06 ? 90 ASP H CG 1 ATOM 6531 O OD1 . ASP C 3 90 ? -166.451 -179.458 234.807 1.00 85.08 ? 90 ASP H OD1 1 ATOM 6532 O OD2 . ASP C 3 90 ? -168.511 -179.724 235.528 1.00 89.66 ? 90 ASP H OD2 1 ATOM 6533 N N . THR C 3 91 ? -164.767 -180.463 239.715 1.00 73.12 ? 91 THR H N 1 ATOM 6534 C CA . THR C 3 91 ? -164.244 -180.122 241.031 1.00 71.83 ? 91 THR H CA 1 ATOM 6535 C C . THR C 3 91 ? -162.882 -179.476 240.869 1.00 69.95 ? 91 THR H C 1 ATOM 6536 O O . THR C 3 91 ? -161.997 -180.039 240.228 1.00 80.60 ? 91 THR H O 1 ATOM 6537 C CB . THR C 3 91 ? -164.117 -181.365 241.926 1.00 70.55 ? 91 THR H CB 1 ATOM 6538 O OG1 . THR C 3 91 ? -165.347 -182.105 241.891 1.00 68.58 ? 91 THR H OG1 1 ATOM 6539 C CG2 . THR C 3 91 ? -163.788 -180.958 243.344 1.00 64.79 ? 91 THR H CG2 1 ATOM 6540 N N . ALA C 3 92 ? -162.703 -178.304 241.460 1.00 67.18 ? 92 ALA H N 1 ATOM 6541 C CA . ALA C 3 92 ? -161.447 -177.570 241.323 1.00 64.67 ? 92 ALA H CA 1 ATOM 6542 C C . ALA C 3 92 ? -161.470 -176.331 242.186 1.00 66.26 ? 92 ALA H C 1 ATOM 6543 O O . ALA C 3 92 ? -162.524 -175.951 242.693 1.00 66.21 ? 92 ALA H O 1 ATOM 6544 C CB . ALA C 3 92 ? -161.197 -177.185 239.868 1.00 66.83 ? 92 ALA H CB 1 ATOM 6545 N N . MET C 3 93 ? -160.315 -175.701 242.370 1.00 62.02 ? 93 MET H N 1 ATOM 6546 C CA . MET C 3 93 ? -160.316 -174.319 242.799 1.00 65.57 ? 93 MET H CA 1 ATOM 6547 C C . MET C 3 93 ? -160.449 -173.445 241.560 1.00 72.83 ? 93 MET H C 1 ATOM 6548 O O . MET C 3 93 ? -159.681 -173.621 240.612 1.00 72.94 ? 93 MET H O 1 ATOM 6549 C CB . MET C 3 93 ? -159.052 -173.980 243.553 1.00 63.21 ? 93 MET H CB 1 ATOM 6550 C CG . MET C 3 93 ? -158.975 -172.524 243.954 1.00 67.98 ? 93 MET H CG 1 ATOM 6551 S SD . MET C 3 93 ? -157.835 -172.379 245.331 1.00 95.46 ? 93 MET H SD 1 ATOM 6552 C CE . MET C 3 93 ? -158.673 -173.377 246.568 1.00 76.96 ? 93 MET H CE 1 ATOM 6553 N N . TYR C 3 94 ? -161.407 -172.515 241.540 1.00 64.77 ? 94 TYR H N 1 ATOM 6554 C CA . TYR C 3 94 ? -161.539 -171.647 240.376 1.00 67.31 ? 94 TYR H CA 1 ATOM 6555 C C . TYR C 3 94 ? -160.870 -170.312 240.615 1.00 69.99 ? 94 TYR H C 1 ATOM 6556 O O . TYR C 3 94 ? -161.114 -169.649 241.621 1.00 66.33 ? 94 TYR H O 1 ATOM 6557 C CB . TYR C 3 94 ? -163.004 -171.449 239.993 1.00 69.43 ? 94 TYR H CB 1 ATOM 6558 C CG . TYR C 3 94 ? -163.572 -172.687 239.354 1.00 67.63 ? 94 TYR H CG 1 ATOM 6559 C CD1 . TYR C 3 94 ? -163.843 -172.730 237.994 1.00 60.89 ? 94 TYR H CD1 1 ATOM 6560 C CD2 . TYR C 3 94 ? -163.790 -173.836 240.109 1.00 65.26 ? 94 TYR H CD2 1 ATOM 6561 C CE1 . TYR C 3 94 ? -164.334 -173.874 237.412 1.00 64.38 ? 94 TYR H CE1 1 ATOM 6562 C CE2 . TYR C 3 94 ? -164.297 -174.978 239.535 1.00 65.38 ? 94 TYR H CE2 1 ATOM 6563 C CZ . TYR C 3 94 ? -164.565 -174.998 238.192 1.00 63.65 ? 94 TYR H CZ 1 ATOM 6564 O OH . TYR C 3 94 ? -165.065 -176.151 237.628 1.00 65.92 ? 94 TYR H OH 1 ATOM 6565 N N . TYR C 3 95 ? -160.011 -169.941 239.671 1.00 72.54 ? 95 TYR H N 1 ATOM 6566 C CA . TYR C 3 95 ? -159.285 -168.688 239.720 1.00 68.01 ? 95 TYR H CA 1 ATOM 6567 C C . TYR C 3 95 ? -159.872 -167.711 238.737 1.00 66.84 ? 95 TYR H C 1 ATOM 6568 O O . TYR C 3 95 ? -160.287 -168.080 237.646 1.00 70.81 ? 95 TYR H O 1 ATOM 6569 C CB . TYR C 3 95 ? -157.800 -168.907 239.411 1.00 70.59 ? 95 TYR H CB 1 ATOM 6570 C CG . TYR C 3 95 ? -157.031 -169.599 240.509 1.00 69.90 ? 95 TYR H CG 1 ATOM 6571 C CD1 . TYR C 3 95 ? -156.733 -168.940 241.686 1.00 70.75 ? 95 TYR H CD1 1 ATOM 6572 C CD2 . TYR C 3 95 ? -156.593 -170.906 240.363 1.00 65.29 ? 95 TYR H CD2 1 ATOM 6573 C CE1 . TYR C 3 95 ? -156.022 -169.570 242.696 1.00 75.84 ? 95 TYR H CE1 1 ATOM 6574 C CE2 . TYR C 3 95 ? -155.875 -171.540 241.365 1.00 64.82 ? 95 TYR H CE2 1 ATOM 6575 C CZ . TYR C 3 95 ? -155.596 -170.873 242.528 1.00 71.14 ? 95 TYR H CZ 1 ATOM 6576 O OH . TYR C 3 95 ? -154.898 -171.499 243.536 1.00 73.97 ? 95 TYR H OH 1 ATOM 6577 N N . CYS C 3 96 ? -159.901 -166.459 239.141 1.00 72.42 ? 96 CYS H N 1 ATOM 6578 C CA . CYS C 3 96 ? -160.233 -165.382 238.243 1.00 75.00 ? 96 CYS H CA 1 ATOM 6579 C C . CYS C 3 96 ? -158.906 -164.692 237.919 1.00 74.48 ? 96 CYS H C 1 ATOM 6580 O O . CYS C 3 96 ? -158.100 -164.443 238.828 1.00 72.60 ? 96 CYS H O 1 ATOM 6581 C CB . CYS C 3 96 ? -161.278 -164.474 238.908 1.00 77.12 ? 96 CYS H CB 1 ATOM 6582 S SG . CYS C 3 96 ? -161.275 -162.727 238.537 1.00 98.31 ? 96 CYS H SG 1 ATOM 6583 N N . ALA C 3 97 ? -158.651 -164.421 236.638 1.00 72.07 ? 97 ALA H N 1 ATOM 6584 C CA . ALA C 3 97 ? -157.334 -163.912 236.230 1.00 68.98 ? 97 ALA H CA 1 ATOM 6585 C C . ALA C 3 97 ? -157.387 -162.823 235.162 1.00 72.98 ? 97 ALA H C 1 ATOM 6586 O O . ALA C 3 97 ? -158.063 -162.974 234.138 1.00 71.00 ? 97 ALA H O 1 ATOM 6587 C CB . ALA C 3 97 ? -156.472 -165.051 235.732 1.00 64.46 ? 97 ALA H CB 1 ATOM 6588 N N . ARG C 3 98 ? -156.674 -161.725 235.407 1.00 72.72 ? 98 ARG H N 1 ATOM 6589 C CA . ARG C 3 98 ? -156.536 -160.663 234.415 1.00 70.42 ? 98 ARG H CA 1 ATOM 6590 C C . ARG C 3 98 ? -155.650 -161.113 233.264 1.00 68.76 ? 98 ARG H C 1 ATOM 6591 O O . ARG C 3 98 ? -154.649 -161.778 233.486 1.00 67.14 ? 98 ARG H O 1 ATOM 6592 C CB . ARG C 3 98 ? -155.970 -159.394 235.057 1.00 71.07 ? 98 ARG H CB 1 ATOM 6593 C CG . ARG C 3 98 ? -156.365 -158.135 234.312 1.00 77.03 ? 98 ARG H CG 1 ATOM 6594 C CD . ARG C 3 98 ? -155.944 -156.859 235.035 1.00 75.11 ? 98 ARG H CD 1 ATOM 6595 N NE . ARG C 3 98 ? -154.539 -156.559 234.817 1.00 80.28 ? 98 ARG H NE 1 ATOM 6596 C CZ . ARG C 3 98 ? -153.920 -155.481 235.283 1.00 81.72 ? 98 ARG H CZ 1 ATOM 6597 N NH1 . ARG C 3 98 ? -154.584 -154.582 235.999 1.00 81.88 ? 98 ARG H NH1 1 ATOM 6598 N NH2 . ARG C 3 98 ? -152.631 -155.302 235.032 1.00 82.03 ? 98 ARG H NH2 1 ATOM 6599 N N . GLY C 3 99 ? -155.992 -160.723 232.040 1.00 71.59 ? 99 GLY H N 1 ATOM 6600 C CA . GLY C 3 99 ? -155.213 -161.139 230.889 1.00 71.44 ? 99 GLY H CA 1 ATOM 6601 C C . GLY C 3 99 ? -155.553 -160.395 229.612 1.00 74.15 ? 99 GLY H C 1 ATOM 6602 O O . GLY C 3 99 ? -155.948 -161.002 228.612 1.00 74.66 ? 99 GLY H O 1 ATOM 6603 N N . GLU C 3 100 ? -155.415 -159.073 229.636 1.00 80.33 ? 100 GLU H N 1 ATOM 6604 C CA . GLU C 3 100 ? -155.723 -158.278 228.454 1.00 77.89 ? 100 GLU H CA 1 ATOM 6605 C C . GLU C 3 100 ? -154.722 -158.483 227.316 1.00 74.33 ? 100 GLU H C 1 ATOM 6606 O O . GLU C 3 100 ? -155.111 -158.484 226.156 1.00 79.29 ? 100 GLU H O 1 ATOM 6607 C CB . GLU C 3 100 ? -155.807 -156.792 228.810 1.00 76.66 ? 100 GLU H CB 1 ATOM 6608 C CG . GLU C 3 100 ? -156.045 -155.874 227.599 1.00 82.52 ? 100 GLU H CG 1 ATOM 6609 C CD . GLU C 3 100 ? -157.396 -156.078 226.914 1.00 82.66 ? 100 GLU H CD 1 ATOM 6610 O OE1 . GLU C 3 100 ? -158.164 -156.962 227.334 1.00 82.02 ? 100 GLU H OE1 1 ATOM 6611 O OE2 . GLU C 3 100 ? -157.697 -155.341 225.954 1.00 88.84 ? 100 GLU H OE2 1 ATOM 6612 N N . VAL C 3 101 ? -153.443 -158.677 227.622 1.00 72.05 ? 101 VAL H N 1 ATOM 6613 C CA . VAL C 3 101 ? -152.486 -158.880 226.538 1.00 71.61 ? 101 VAL H CA 1 ATOM 6614 C C . VAL C 3 101 ? -152.082 -160.351 226.470 1.00 67.99 ? 101 VAL H C 1 ATOM 6615 O O . VAL C 3 101 ? -151.580 -160.914 227.438 1.00 71.83 ? 101 VAL H O 1 ATOM 6616 C CB . VAL C 3 101 ? -151.218 -157.977 226.687 1.00 67.75 ? 101 VAL H CB 1 ATOM 6617 C CG1 . VAL C 3 101 ? -150.172 -158.322 225.626 1.00 62.86 ? 101 VAL H CG1 1 ATOM 6618 C CG2 . VAL C 3 101 ? -151.580 -156.523 226.582 1.00 58.04 ? 101 VAL H CG2 1 ATOM 6619 N N . ARG C 3 102 ? -152.316 -160.969 225.322 1.00 64.64 ? 102 ARG H N 1 ATOM 6620 C CA . ARG C 3 102 ? -151.872 -162.331 225.097 1.00 68.16 ? 102 ARG H CA 1 ATOM 6621 C C . ARG C 3 102 ? -150.354 -162.437 225.116 1.00 73.57 ? 102 ARG H C 1 ATOM 6622 O O . ARG C 3 102 ? -149.784 -163.447 225.513 1.00 75.48 ? 102 ARG H O 1 ATOM 6623 C CB . ARG C 3 102 ? -152.382 -162.854 223.756 1.00 68.12 ? 102 ARG H CB 1 ATOM 6624 C CG . ARG C 3 102 ? -153.868 -162.804 223.560 1.00 61.73 ? 102 ARG H CG 1 ATOM 6625 C CD . ARG C 3 102 ? -154.245 -163.676 222.394 1.00 64.21 ? 102 ARG H CD 1 ATOM 6626 N NE . ARG C 3 102 ? -155.689 -163.730 222.166 1.00 72.90 ? 102 ARG H NE 1 ATOM 6627 C CZ . ARG C 3 102 ? -156.296 -163.286 221.072 1.00 73.50 ? 102 ARG H CZ 1 ATOM 6628 N NH1 . ARG C 3 102 ? -157.615 -163.386 220.955 1.00 71.03 ? 102 ARG H NH1 1 ATOM 6629 N NH2 . ARG C 3 102 ? -155.578 -162.741 220.100 1.00 75.48 ? 102 ARG H NH2 1 ATOM 6630 N N . GLN C 3 103 ? -149.678 -161.397 224.667 1.00 74.22 ? 103 GLN H N 1 ATOM 6631 C CA . GLN C 3 103 ? -148.240 -161.503 224.584 1.00 68.20 ? 103 GLN H CA 1 ATOM 6632 C C . GLN C 3 103 ? -147.676 -161.377 225.991 1.00 71.38 ? 103 GLN H C 1 ATOM 6633 O O . GLN C 3 103 ? -146.485 -161.605 226.205 1.00 77.14 ? 103 GLN H O 1 ATOM 6634 C CB . GLN C 3 103 ? -147.648 -160.443 223.641 1.00 71.95 ? 103 GLN H CB 1 ATOM 6635 C CG . GLN C 3 103 ? -147.840 -160.714 222.146 1.00 74.62 ? 103 GLN H CG 1 ATOM 6636 C CD . GLN C 3 103 ? -149.233 -160.347 221.644 1.00 75.71 ? 103 GLN H CD 1 ATOM 6637 O OE1 . GLN C 3 103 ? -150.032 -159.747 222.367 1.00 74.49 ? 103 GLN H OE1 1 ATOM 6638 N NE2 . GLN C 3 103 ? -149.524 -160.707 220.399 1.00 74.06 ? 103 GLN H NE2 1 ATOM 6639 N N . ARG C 3 104 ? -148.515 -160.992 226.954 1.00 70.04 ? 104 ARG H N 1 ATOM 6640 C CA . ARG C 3 104 ? -148.004 -160.766 228.301 1.00 74.86 ? 104 ARG H CA 1 ATOM 6641 C C . ARG C 3 104 ? -148.523 -161.742 229.375 1.00 75.24 ? 104 ARG H C 1 ATOM 6642 O O . ARG C 3 104 ? -148.011 -161.759 230.499 1.00 76.03 ? 104 ARG H O 1 ATOM 6643 C CB . ARG C 3 104 ? -148.300 -159.329 228.732 1.00 77.57 ? 104 ARG H CB 1 ATOM 6644 C CG . ARG C 3 104 ? -147.334 -158.862 229.804 1.00 93.60 ? 104 ARG H CG 1 ATOM 6645 C CD . ARG C 3 104 ? -147.797 -157.637 230.590 1.00 103.71 ? 104 ARG H CD 1 ATOM 6646 N NE . ARG C 3 104 ? -147.167 -157.639 231.914 1.00 107.08 ? 104 ARG H NE 1 ATOM 6647 C CZ . ARG C 3 104 ? -145.972 -157.112 232.184 1.00 109.46 ? 104 ARG H CZ 1 ATOM 6648 N NH1 . ARG C 3 104 ? -145.276 -156.509 231.215 1.00 98.04 ? 104 ARG H NH1 1 ATOM 6649 N NH2 . ARG C 3 104 ? -145.477 -157.185 233.427 1.00 105.97 ? 104 ARG H NH2 1 ATOM 6650 N N . GLY C 3 105 ? -149.518 -162.560 229.045 1.00 73.62 ? 105 GLY H N 1 ATOM 6651 C CA . GLY C 3 105 ? -150.029 -163.526 230.006 1.00 69.51 ? 105 GLY H CA 1 ATOM 6652 C C . GLY C 3 105 ? -151.050 -163.045 231.027 1.00 73.99 ? 105 GLY H C 1 ATOM 6653 O O . GLY C 3 105 ? -151.550 -161.909 230.967 1.00 77.63 ? 105 GLY H O 1 ATOM 6654 N N . PHE C 3 106 ? -151.372 -163.932 231.971 1.00 74.76 ? 106 PHE H N 1 ATOM 6655 C CA . PHE C 3 106 ? -152.254 -163.613 233.101 1.00 71.17 ? 106 PHE H CA 1 ATOM 6656 C C . PHE C 3 106 ? -151.478 -162.937 234.226 1.00 69.87 ? 106 PHE H C 1 ATOM 6657 O O . PHE C 3 106 ? -150.912 -163.614 235.084 1.00 65.06 ? 106 PHE H O 1 ATOM 6658 C CB . PHE C 3 106 ? -152.939 -164.879 233.622 1.00 59.81 ? 106 PHE H CB 1 ATOM 6659 C CG . PHE C 3 106 ? -153.823 -165.547 232.602 1.00 65.88 ? 106 PHE H CG 1 ATOM 6660 C CD1 . PHE C 3 106 ? -155.003 -164.950 232.186 1.00 62.85 ? 106 PHE H CD1 1 ATOM 6661 C CD2 . PHE C 3 106 ? -153.479 -166.777 232.065 1.00 65.71 ? 106 PHE H CD2 1 ATOM 6662 C CE1 . PHE C 3 106 ? -155.813 -165.564 231.255 1.00 65.25 ? 106 PHE H CE1 1 ATOM 6663 C CE2 . PHE C 3 106 ? -154.296 -167.397 231.137 1.00 60.06 ? 106 PHE H CE2 1 ATOM 6664 C CZ . PHE C 3 106 ? -155.458 -166.786 230.725 1.00 60.61 ? 106 PHE H CZ 1 ATOM 6665 N N . ASP C 3 107 ? -151.440 -161.603 234.202 1.00 69.46 ? 107 ASP H N 1 ATOM 6666 C CA . ASP C 3 107 ? -150.577 -160.840 235.108 1.00 69.64 ? 107 ASP H CA 1 ATOM 6667 C C . ASP C 3 107 ? -151.032 -160.758 236.581 1.00 77.66 ? 107 ASP H C 1 ATOM 6668 O O . ASP C 3 107 ? -150.202 -160.505 237.462 1.00 78.70 ? 107 ASP H O 1 ATOM 6669 C CB . ASP C 3 107 ? -150.369 -159.426 234.562 1.00 68.73 ? 107 ASP H CB 1 ATOM 6670 C CG . ASP C 3 107 ? -151.662 -158.726 234.210 1.00 78.89 ? 107 ASP H CG 1 ATOM 6671 O OD1 . ASP C 3 107 ? -152.704 -159.395 234.062 1.00 84.30 ? 107 ASP H OD1 1 ATOM 6672 O OD2 . ASP C 3 107 ? -151.626 -157.491 234.042 1.00 84.38 ? 107 ASP H OD2 1 ATOM 6673 N N . TYR C 3 108 ? -152.317 -160.996 236.864 1.00 74.84 ? 108 TYR H N 1 ATOM 6674 C CA . TYR C 3 108 ? -152.820 -161.005 238.250 1.00 71.99 ? 108 TYR H CA 1 ATOM 6675 C C . TYR C 3 108 ? -153.851 -162.113 238.471 1.00 73.23 ? 108 TYR H C 1 ATOM 6676 O O . TYR C 3 108 ? -154.675 -162.375 237.597 1.00 77.00 ? 108 TYR H O 1 ATOM 6677 C CB . TYR C 3 108 ? -153.444 -159.650 238.626 1.00 68.89 ? 108 TYR H CB 1 ATOM 6678 C CG . TYR C 3 108 ? -152.458 -158.508 238.836 1.00 77.03 ? 108 TYR H CG 1 ATOM 6679 C CD1 . TYR C 3 108 ? -151.299 -158.678 239.576 1.00 85.34 ? 108 TYR H CD1 1 ATOM 6680 C CD2 . TYR C 3 108 ? -152.688 -157.267 238.277 1.00 86.23 ? 108 TYR H CD2 1 ATOM 6681 C CE1 . TYR C 3 108 ? -150.397 -157.644 239.757 1.00 91.76 ? 108 TYR H CE1 1 ATOM 6682 C CE2 . TYR C 3 108 ? -151.800 -156.215 238.458 1.00 92.41 ? 108 TYR H CE2 1 ATOM 6683 C CZ . TYR C 3 108 ? -150.652 -156.411 239.201 1.00 91.60 ? 108 TYR H CZ 1 ATOM 6684 O OH . TYR C 3 108 ? -149.766 -155.372 239.375 1.00 98.19 ? 108 TYR H OH 1 ATOM 6685 N N . TRP C 3 109 ? -153.825 -162.734 239.650 1.00 69.87 ? 109 TRP H N 1 ATOM 6686 C CA . TRP C 3 109 ? -154.743 -163.826 239.984 1.00 67.33 ? 109 TRP H CA 1 ATOM 6687 C C . TRP C 3 109 ? -155.468 -163.620 241.323 1.00 69.82 ? 109 TRP H C 1 ATOM 6688 O O . TRP C 3 109 ? -154.905 -163.052 242.260 1.00 69.05 ? 109 TRP H O 1 ATOM 6689 C CB . TRP C 3 109 ? -153.988 -165.150 240.064 1.00 69.10 ? 109 TRP H CB 1 ATOM 6690 C CG . TRP C 3 109 ? -153.387 -165.642 238.787 1.00 69.71 ? 109 TRP H CG 1 ATOM 6691 C CD1 . TRP C 3 109 ? -152.418 -165.033 238.051 1.00 69.16 ? 109 TRP H CD1 1 ATOM 6692 C CD2 . TRP C 3 109 ? -153.672 -166.884 238.126 1.00 66.36 ? 109 TRP H CD2 1 ATOM 6693 N NE1 . TRP C 3 109 ? -152.102 -165.803 236.958 1.00 70.39 ? 109 TRP H NE1 1 ATOM 6694 C CE2 . TRP C 3 109 ? -152.862 -166.943 236.978 1.00 67.10 ? 109 TRP H CE2 1 ATOM 6695 C CE3 . TRP C 3 109 ? -154.548 -167.939 238.383 1.00 66.60 ? 109 TRP H CE3 1 ATOM 6696 C CZ2 . TRP C 3 109 ? -152.897 -168.023 236.088 1.00 63.13 ? 109 TRP H CZ2 1 ATOM 6697 C CZ3 . TRP C 3 109 ? -154.583 -169.011 237.494 1.00 70.85 ? 109 TRP H CZ3 1 ATOM 6698 C CH2 . TRP C 3 109 ? -153.760 -169.045 236.369 1.00 66.72 ? 109 TRP H CH2 1 ATOM 6699 N N . GLY C 3 110 ? -156.679 -164.158 241.446 1.00 70.06 ? 110 GLY H N 1 ATOM 6700 C CA . GLY C 3 110 ? -157.399 -164.098 242.712 1.00 71.11 ? 110 GLY H CA 1 ATOM 6701 C C . GLY C 3 110 ? -156.869 -165.125 243.698 1.00 69.97 ? 110 GLY H C 1 ATOM 6702 O O . GLY C 3 110 ? -155.869 -165.780 243.425 1.00 69.48 ? 110 GLY H O 1 ATOM 6703 N N . GLN C 3 111 ? -157.472 -165.234 244.878 1.00 76.47 ? 111 GLN H N 1 ATOM 6704 C CA . GLN C 3 111 ? -157.025 -166.259 245.828 1.00 77.29 ? 111 GLN H CA 1 ATOM 6705 C C . GLN C 3 111 ? -157.737 -167.591 245.567 1.00 75.30 ? 111 GLN H C 1 ATOM 6706 O O . GLN C 3 111 ? -157.335 -168.649 246.061 1.00 68.83 ? 111 GLN H O 1 ATOM 6707 C CB . GLN C 3 111 ? -157.244 -165.796 247.271 1.00 70.26 ? 111 GLN H CB 1 ATOM 6708 C CG . GLN C 3 111 ? -158.674 -165.948 247.764 1.00 84.23 ? 111 GLN H CG 1 ATOM 6709 C CD . GLN C 3 111 ? -159.625 -164.910 247.188 1.00 95.34 ? 111 GLN H CD 1 ATOM 6710 O OE1 . GLN C 3 111 ? -159.233 -163.764 246.916 1.00 93.15 ? 111 GLN H OE1 1 ATOM 6711 N NE2 . GLN C 3 111 ? -160.889 -165.306 247.001 1.00 83.37 ? 111 GLN H NE2 1 ATOM 6712 N N . GLY C 3 112 ? -158.783 -167.527 244.751 1.00 72.07 ? 112 GLY H N 1 ATOM 6713 C CA . GLY C 3 112 ? -159.498 -168.706 244.318 1.00 68.07 ? 112 GLY H CA 1 ATOM 6714 C C . GLY C 3 112 ? -160.676 -169.031 245.203 1.00 76.71 ? 112 GLY H C 1 ATOM 6715 O O . GLY C 3 112 ? -160.711 -168.654 246.372 1.00 81.83 ? 112 GLY H O 1 ATOM 6716 N N . THR C 3 113 ? -161.641 -169.747 244.636 1.00 70.50 ? 113 THR H N 1 ATOM 6717 C CA . THR C 3 113 ? -162.809 -170.210 245.363 1.00 66.19 ? 113 THR H CA 1 ATOM 6718 C C . THR C 3 113 ? -163.068 -171.671 244.972 1.00 69.45 ? 113 THR H C 1 ATOM 6719 O O . THR C 3 113 ? -162.996 -172.029 243.795 1.00 69.01 ? 113 THR H O 1 ATOM 6720 C CB . THR C 3 113 ? -164.035 -169.313 245.060 1.00 73.75 ? 113 THR H CB 1 ATOM 6721 O OG1 . THR C 3 113 ? -165.160 -169.720 245.847 1.00 76.87 ? 113 THR H OG1 1 ATOM 6722 C CG2 . THR C 3 113 ? -164.397 -169.358 243.585 1.00 70.25 ? 113 THR H CG2 1 ATOM 6723 N N . THR C 3 114 ? -163.359 -172.520 245.953 1.00 67.26 ? 114 THR H N 1 ATOM 6724 C CA . THR C 3 114 ? -163.391 -173.964 245.713 1.00 65.72 ? 114 THR H CA 1 ATOM 6725 C C . THR C 3 114 ? -164.752 -174.573 245.364 1.00 70.83 ? 114 THR H C 1 ATOM 6726 O O . THR C 3 114 ? -165.723 -174.481 246.117 1.00 71.76 ? 114 THR H O 1 ATOM 6727 C CB . THR C 3 114 ? -162.866 -174.737 246.928 1.00 62.68 ? 114 THR H CB 1 ATOM 6728 O OG1 . THR C 3 114 ? -161.460 -174.499 247.079 1.00 73.80 ? 114 THR H OG1 1 ATOM 6729 C CG2 . THR C 3 114 ? -163.096 -176.224 246.725 1.00 66.68 ? 114 THR H CG2 1 ATOM 6730 N N . LEU C 3 115 ? -164.802 -175.243 244.224 1.00 70.17 ? 115 LEU H N 1 ATOM 6731 C CA . LEU C 3 115 ? -165.993 -175.963 243.848 1.00 69.85 ? 115 LEU H CA 1 ATOM 6732 C C . LEU C 3 115 ? -165.797 -177.427 244.176 1.00 69.99 ? 115 LEU H C 1 ATOM 6733 O O . LEU C 3 115 ? -164.766 -178.009 243.835 1.00 68.34 ? 115 LEU H O 1 ATOM 6734 C CB . LEU C 3 115 ? -166.299 -175.784 242.360 1.00 73.18 ? 115 LEU H CB 1 ATOM 6735 C CG . LEU C 3 115 ? -167.634 -176.389 241.927 1.00 72.45 ? 115 LEU H CG 1 ATOM 6736 C CD1 . LEU C 3 115 ? -168.714 -175.554 242.573 1.00 72.39 ? 115 LEU H CD1 1 ATOM 6737 C CD2 . LEU C 3 115 ? -167.782 -176.440 240.400 1.00 66.24 ? 115 LEU H CD2 1 ATOM 6738 N N . THR C 3 116 ? -166.782 -178.026 244.839 1.00 71.34 ? 116 THR H N 1 ATOM 6739 C CA . THR C 3 116 ? -166.772 -179.470 245.038 1.00 70.44 ? 116 THR H CA 1 ATOM 6740 C C . THR C 3 116 ? -168.080 -180.075 244.544 1.00 70.71 ? 116 THR H C 1 ATOM 6741 O O . THR C 3 116 ? -169.160 -179.712 245.006 1.00 72.65 ? 116 THR H O 1 ATOM 6742 C CB . THR C 3 116 ? -166.554 -179.855 246.506 1.00 65.65 ? 116 THR H CB 1 ATOM 6743 O OG1 . THR C 3 116 ? -165.373 -179.217 247.007 1.00 75.72 ? 116 THR H OG1 1 ATOM 6744 C CG2 . THR C 3 116 ? -166.373 -181.333 246.623 1.00 62.15 ? 116 THR H CG2 1 ATOM 6745 N N . VAL C 3 117 ? -167.968 -180.990 243.590 1.00 66.47 ? 117 VAL H N 1 ATOM 6746 C CA . VAL C 3 117 ? -169.124 -181.631 243.009 1.00 70.95 ? 117 VAL H CA 1 ATOM 6747 C C . VAL C 3 117 ? -169.139 -183.089 243.449 1.00 75.18 ? 117 VAL H C 1 ATOM 6748 O O . VAL C 3 117 ? -168.304 -183.885 243.019 1.00 78.53 ? 117 VAL H O 1 ATOM 6749 C CB . VAL C 3 117 ? -169.114 -181.533 241.465 1.00 76.22 ? 117 VAL H CB 1 ATOM 6750 C CG1 . VAL C 3 117 ? -170.383 -182.149 240.877 1.00 76.34 ? 117 VAL H CG1 1 ATOM 6751 C CG2 . VAL C 3 117 ? -168.967 -180.086 241.028 1.00 69.97 ? 117 VAL H CG2 1 ATOM 6752 N N . SER C 3 118 ? -170.077 -183.440 244.323 1.00 78.12 ? 118 SER H N 1 ATOM 6753 C CA . SER C 3 118 ? -170.154 -184.804 244.831 1.00 72.15 ? 118 SER H CA 1 ATOM 6754 C C . SER C 3 118 ? -171.561 -185.169 245.234 1.00 73.59 ? 118 SER H C 1 ATOM 6755 O O . SER C 3 118 ? -172.381 -184.292 245.497 1.00 76.46 ? 118 SER H O 1 ATOM 6756 C CB . SER C 3 118 ? -169.234 -184.994 246.030 1.00 69.84 ? 118 SER H CB 1 ATOM 6757 O OG . SER C 3 118 ? -169.320 -186.329 246.492 1.00 75.26 ? 118 SER H OG 1 ATOM 6758 N N . SER C 3 119 ? -171.847 -186.464 245.271 1.00 75.97 ? 119 SER H N 1 ATOM 6759 C CA . SER C 3 119 ? -173.106 -186.924 245.839 1.00 74.57 ? 119 SER H CA 1 ATOM 6760 C C . SER C 3 119 ? -173.024 -187.090 247.356 1.00 77.19 ? 119 SER H C 1 ATOM 6761 O O . SER C 3 119 ? -174.041 -187.316 248.023 1.00 79.71 ? 119 SER H O 1 ATOM 6762 C CB . SER C 3 119 ? -173.536 -188.231 245.184 1.00 76.50 ? 119 SER H CB 1 ATOM 6763 O OG . SER C 3 119 ? -174.196 -187.949 243.960 1.00 92.45 ? 119 SER H OG 1 ATOM 6764 N N . ALA C 3 120 ? -171.818 -186.967 247.902 1.00 68.25 ? 120 ALA H N 1 ATOM 6765 C CA . ALA C 3 120 ? -171.627 -187.160 249.326 1.00 72.91 ? 120 ALA H CA 1 ATOM 6766 C C . ALA C 3 120 ? -172.399 -186.112 250.143 1.00 79.90 ? 120 ALA H C 1 ATOM 6767 O O . ALA C 3 120 ? -172.461 -184.932 249.782 1.00 77.57 ? 120 ALA H O 1 ATOM 6768 C CB . ALA C 3 120 ? -170.151 -187.118 249.663 1.00 71.04 ? 120 ALA H CB 1 ATOM 6769 N N . LYS C 3 121 ? -173.028 -186.570 251.224 1.00 80.49 ? 121 LYS H N 1 ATOM 6770 C CA . LYS C 3 121 ? -173.647 -185.666 252.199 1.00 81.28 ? 121 LYS H CA 1 ATOM 6771 C C . LYS C 3 121 ? -172.608 -185.025 253.118 1.00 79.66 ? 121 LYS H C 1 ATOM 6772 O O . LYS C 3 121 ? -171.630 -185.664 253.506 1.00 78.16 ? 121 LYS H O 1 ATOM 6773 C CB . LYS C 3 121 ? -174.697 -186.414 253.037 1.00 80.31 ? 121 LYS H CB 1 ATOM 6774 C CG . LYS C 3 121 ? -176.080 -186.457 252.381 1.00 92.21 ? 121 LYS H CG 1 ATOM 6775 C CD . LYS C 3 121 ? -176.852 -187.755 252.674 1.00 94.77 ? 121 LYS H CD 1 ATOM 6776 C CE . LYS C 3 121 ? -177.045 -187.995 254.179 1.00 107.88 ? 121 LYS H CE 1 ATOM 6777 N NZ . LYS C 3 121 ? -178.347 -188.682 254.495 1.00 97.08 ? 121 LYS H NZ 1 ATOM 6778 N N . THR C 3 122 ? -172.849 -183.772 253.494 1.00 79.47 ? 122 THR H N 1 ATOM 6779 C CA . THR C 3 122 ? -172.007 -183.075 254.461 1.00 75.63 ? 122 THR H CA 1 ATOM 6780 C C . THR C 3 122 ? -172.066 -183.773 255.810 1.00 78.43 ? 122 THR H C 1 ATOM 6781 O O . THR C 3 122 ? -173.163 -184.083 256.286 1.00 80.92 ? 122 THR H O 1 ATOM 6782 C CB . THR C 3 122 ? -172.468 -181.615 254.647 1.00 73.04 ? 122 THR H CB 1 ATOM 6783 O OG1 . THR C 3 122 ? -172.299 -180.885 253.426 1.00 77.16 ? 122 THR H OG1 1 ATOM 6784 C CG2 . THR C 3 122 ? -171.695 -180.951 255.760 1.00 70.88 ? 122 THR H CG2 1 ATOM 6785 N N . THR C 3 123 ? -170.914 -183.996 256.448 1.00 73.47 ? 123 THR H N 1 ATOM 6786 C CA . THR C 3 123 ? -170.919 -184.576 257.793 1.00 79.41 ? 123 THR H CA 1 ATOM 6787 C C . THR C 3 123 ? -169.779 -184.021 258.671 1.00 78.34 ? 123 THR H C 1 ATOM 6788 O O . THR C 3 123 ? -168.677 -183.756 258.197 1.00 77.01 ? 123 THR H O 1 ATOM 6789 C CB . THR C 3 123 ? -170.847 -186.143 257.756 1.00 74.73 ? 123 THR H CB 1 ATOM 6790 O OG1 . THR C 3 123 ? -169.488 -186.582 257.716 1.00 85.03 ? 123 THR H OG1 1 ATOM 6791 C CG2 . THR C 3 123 ? -171.585 -186.705 256.555 1.00 78.00 ? 123 THR H CG2 1 ATOM 6792 N N . ALA C 3 124 ? -170.080 -183.828 259.954 1.00 78.96 ? 124 ALA H N 1 ATOM 6793 C CA . ALA C 3 124 ? -169.160 -183.207 260.899 1.00 75.87 ? 124 ALA H CA 1 ATOM 6794 C C . ALA C 3 124 ? -168.080 -184.170 261.348 1.00 80.15 ? 124 ALA H C 1 ATOM 6795 O O . ALA C 3 124 ? -168.346 -185.351 261.564 1.00 84.03 ? 124 ALA H O 1 ATOM 6796 C CB . ALA C 3 124 ? -169.917 -182.678 262.100 1.00 75.08 ? 124 ALA H CB 1 ATOM 6797 N N . PRO C 3 125 ? -166.847 -183.661 261.491 1.00 77.29 ? 125 PRO H N 1 ATOM 6798 C CA . PRO C 3 125 ? -165.736 -184.474 261.989 1.00 77.04 ? 125 PRO H CA 1 ATOM 6799 C C . PRO C 3 125 ? -165.941 -184.886 263.432 1.00 79.25 ? 125 PRO H C 1 ATOM 6800 O O . PRO C 3 125 ? -166.594 -184.167 264.173 1.00 83.80 ? 125 PRO H O 1 ATOM 6801 C CB . PRO C 3 125 ? -164.531 -183.534 261.873 1.00 76.89 ? 125 PRO H CB 1 ATOM 6802 C CG . PRO C 3 125 ? -165.116 -182.165 261.938 1.00 80.30 ? 125 PRO H CG 1 ATOM 6803 C CD . PRO C 3 125 ? -166.457 -182.261 261.266 1.00 79.73 ? 125 PRO H CD 1 ATOM 6804 N N . SER C 3 126 ? -165.435 -186.055 263.802 1.00 78.63 ? 126 SER H N 1 ATOM 6805 C CA . SER C 3 126 ? -165.139 -186.350 265.191 1.00 79.86 ? 126 SER H CA 1 ATOM 6806 C C . SER C 3 126 ? -163.712 -185.924 265.446 1.00 82.29 ? 126 SER H C 1 ATOM 6807 O O . SER C 3 126 ? -162.821 -186.333 264.707 1.00 85.28 ? 126 SER H O 1 ATOM 6808 C CB . SER C 3 126 ? -165.294 -187.838 265.476 1.00 82.96 ? 126 SER H CB 1 ATOM 6809 O OG . SER C 3 126 ? -166.399 -188.360 264.766 1.00 89.93 ? 126 SER H OG 1 ATOM 6810 N N . VAL C 3 127 ? -163.471 -185.112 266.467 1.00 81.32 ? 127 VAL H N 1 ATOM 6811 C CA . VAL C 3 127 ? -162.091 -184.789 266.797 1.00 84.17 ? 127 VAL H CA 1 ATOM 6812 C C . VAL C 3 127 ? -161.652 -185.559 268.031 1.00 84.21 ? 127 VAL H C 1 ATOM 6813 O O . VAL C 3 127 ? -162.329 -185.559 269.050 1.00 90.97 ? 127 VAL H O 1 ATOM 6814 C CB . VAL C 3 127 ? -161.891 -183.282 267.005 1.00 83.12 ? 127 VAL H CB 1 ATOM 6815 C CG1 . VAL C 3 127 ? -162.323 -182.530 265.758 1.00 81.94 ? 127 VAL H CG1 1 ATOM 6816 C CG2 . VAL C 3 127 ? -162.687 -182.806 268.190 1.00 94.70 ? 127 VAL H CG2 1 ATOM 6817 N N . TYR C 3 128 ? -160.509 -186.224 267.929 1.00 89.18 ? 128 TYR H N 1 ATOM 6818 C CA . TYR C 3 128 ? -159.994 -187.034 269.030 1.00 92.24 ? 128 TYR H CA 1 ATOM 6819 C C . TYR C 3 128 ? -158.634 -186.513 269.472 1.00 90.40 ? 128 TYR H C 1 ATOM 6820 O O . TYR C 3 128 ? -157.772 -186.238 268.632 1.00 87.26 ? 128 TYR H O 1 ATOM 6821 C CB . TYR C 3 128 ? -159.868 -188.508 268.614 1.00 88.90 ? 128 TYR H CB 1 ATOM 6822 C CG . TYR C 3 128 ? -161.143 -189.141 268.113 1.00 90.69 ? 128 TYR H CG 1 ATOM 6823 C CD1 . TYR C 3 128 ? -162.313 -189.084 268.861 1.00 90.71 ? 128 TYR H CD1 1 ATOM 6824 C CD2 . TYR C 3 128 ? -161.184 -189.787 266.880 1.00 90.95 ? 128 TYR H CD2 1 ATOM 6825 C CE1 . TYR C 3 128 ? -163.485 -189.659 268.403 1.00 86.27 ? 128 TYR H CE1 1 ATOM 6826 C CE2 . TYR C 3 128 ? -162.359 -190.360 266.417 1.00 89.67 ? 128 TYR H CE2 1 ATOM 6827 C CZ . TYR C 3 128 ? -163.504 -190.290 267.181 1.00 87.78 ? 128 TYR H CZ 1 ATOM 6828 O OH . TYR C 3 128 ? -164.674 -190.861 266.725 1.00 95.55 ? 128 TYR H OH 1 ATOM 6829 N N . PRO C 3 129 ? -158.446 -186.379 270.788 1.00 95.55 ? 129 PRO H N 1 ATOM 6830 C CA . PRO C 3 129 ? -157.138 -186.077 271.370 1.00 94.23 ? 129 PRO H CA 1 ATOM 6831 C C . PRO C 3 129 ? -156.160 -187.215 271.112 1.00 95.36 ? 129 PRO H C 1 ATOM 6832 O O . PRO C 3 129 ? -156.570 -188.379 271.103 1.00 100.96 ? 129 PRO H O 1 ATOM 6833 C CB . PRO C 3 129 ? -157.441 -185.937 272.859 1.00 94.33 ? 129 PRO H CB 1 ATOM 6834 C CG . PRO C 3 129 ? -158.657 -186.788 273.063 1.00 95.43 ? 129 PRO H CG 1 ATOM 6835 C CD . PRO C 3 129 ? -159.470 -186.624 271.820 1.00 95.91 ? 129 PRO H CD 1 ATOM 6836 N N . LEU C 3 130 ? -154.889 -186.899 270.923 1.00 89.70 ? 130 LEU H N 1 ATOM 6837 C CA . LEU C 3 130 ? -153.892 -187.950 270.843 1.00 94.19 ? 130 LEU H CA 1 ATOM 6838 C C . LEU C 3 130 ? -152.856 -187.766 271.947 1.00 100.24 ? 130 LEU H C 1 ATOM 6839 O O . LEU C 3 130 ? -151.821 -187.123 271.746 1.00 103.22 ? 130 LEU H O 1 ATOM 6840 C CB . LEU C 3 130 ? -153.221 -187.989 269.466 1.00 97.11 ? 130 LEU H CB 1 ATOM 6841 C CG . LEU C 3 130 ? -154.092 -188.250 268.232 1.00 94.44 ? 130 LEU H CG 1 ATOM 6842 C CD1 . LEU C 3 130 ? -153.237 -188.296 266.969 1.00 88.65 ? 130 LEU H CD1 1 ATOM 6843 C CD2 . LEU C 3 130 ? -154.905 -189.522 268.387 1.00 88.19 ? 130 LEU H CD2 1 ATOM 6844 N N . ALA C 3 131 ? -153.176 -188.297 273.129 1.00 102.89 ? 131 ALA H N 1 ATOM 6845 C CA . ALA C 3 131 ? -152.232 -188.407 274.240 1.00 103.48 ? 131 ALA H CA 1 ATOM 6846 C C . ALA C 3 131 ? -151.302 -189.608 274.071 1.00 108.14 ? 131 ALA H C 1 ATOM 6847 O O . ALA C 3 131 ? -151.749 -190.675 273.636 1.00 107.75 ? 131 ALA H O 1 ATOM 6848 C CB . ALA C 3 131 ? -152.980 -188.506 275.561 1.00 108.69 ? 131 ALA H CB 1 ATOM 6849 N N . PRO C 3 132 ? -150.021 -189.440 274.450 1.00 106.16 ? 132 PRO H N 1 ATOM 6850 C CA . PRO C 3 132 ? -148.905 -190.401 274.429 1.00 101.98 ? 132 PRO H CA 1 ATOM 6851 C C . PRO C 3 132 ? -149.081 -191.599 275.366 1.00 106.54 ? 132 PRO H C 1 ATOM 6852 O O . PRO C 3 132 ? -149.769 -191.493 276.374 1.00 112.63 ? 132 PRO H O 1 ATOM 6853 C CB . PRO C 3 132 ? -147.703 -189.556 274.868 1.00 97.96 ? 132 PRO H CB 1 ATOM 6854 C CG . PRO C 3 132 ? -148.267 -188.333 275.474 1.00 104.10 ? 132 PRO H CG 1 ATOM 6855 C CD . PRO C 3 132 ? -149.571 -188.084 274.811 1.00 103.92 ? 132 PRO H CD 1 ATOM 6856 N N . VAL C 3 133 ? -148.467 -192.725 274.999 1.00 112.11 ? 133 VAL H N 1 ATOM 6857 C CA . VAL C 3 133 ? -148.612 -194.017 275.689 1.00 126.80 ? 133 VAL H CA 1 ATOM 6858 C C . VAL C 3 133 ? -148.208 -193.984 277.173 1.00 136.55 ? 133 VAL H C 1 ATOM 6859 O O . VAL C 3 133 ? -147.607 -193.015 277.623 1.00 133.88 ? 133 VAL H O 1 ATOM 6860 C CB . VAL C 3 133 ? -147.759 -195.107 274.979 1.00 125.10 ? 133 VAL H CB 1 ATOM 6861 C CG1 . VAL C 3 133 ? -148.082 -196.504 275.518 1.00 127.00 ? 133 VAL H CG1 1 ATOM 6862 C CG2 . VAL C 3 133 ? -147.959 -195.049 273.467 1.00 108.79 ? 133 VAL H CG2 1 ATOM 6863 N N . CYS C 3 134 ? -148.570 -195.029 277.927 1.00 143.15 ? 134 CYS H N 1 ATOM 6864 C CA . CYS C 3 134 ? -148.155 -195.185 279.331 1.00 143.69 ? 134 CYS H CA 1 ATOM 6865 C C . CYS C 3 134 ? -146.620 -195.257 279.443 1.00 149.70 ? 134 CYS H C 1 ATOM 6866 O O . CYS C 3 134 ? -145.962 -195.930 278.643 1.00 152.92 ? 134 CYS H O 1 ATOM 6867 C CB . CYS C 3 134 ? -148.782 -196.444 279.942 1.00 143.49 ? 134 CYS H CB 1 ATOM 6868 S SG . CYS C 3 134 ? -150.525 -196.738 279.524 1.00 137.45 ? 134 CYS H SG 1 ATOM 6869 N N . GLY C 3 135 ? -146.051 -194.581 280.440 1.00 150.50 ? 135 GLY H N 1 ATOM 6870 C CA . GLY C 3 135 ? -144.627 -194.278 280.418 1.00 151.57 ? 135 GLY H CA 1 ATOM 6871 C C . GLY C 3 135 ? -144.522 -193.225 279.329 1.00 157.19 ? 135 GLY H C 1 ATOM 6872 O O . GLY C 3 135 ? -145.510 -192.548 279.063 1.00 158.38 ? 135 GLY H O 1 ATOM 6873 N N . ASP C 3 136 ? -143.349 -193.006 278.744 1.00 160.04 ? 136 ASP H N 1 ATOM 6874 C CA . ASP C 3 136 ? -142.064 -193.336 279.336 1.00 163.76 ? 136 ASP H CA 1 ATOM 6875 C C . ASP C 3 136 ? -141.132 -192.179 278.969 1.00 158.34 ? 136 ASP H C 1 ATOM 6876 O O . ASP C 3 136 ? -140.407 -192.211 277.972 1.00 156.42 ? 136 ASP H O 1 ATOM 6877 C CB . ASP C 3 136 ? -141.522 -194.687 278.855 1.00 163.86 ? 136 ASP H CB 1 ATOM 6878 C CG . ASP C 3 136 ? -140.193 -195.053 279.515 1.00 162.64 ? 136 ASP H CG 1 ATOM 6879 O OD1 . ASP C 3 136 ? -139.759 -194.321 280.432 1.00 163.25 ? 136 ASP H OD1 1 ATOM 6880 O OD2 . ASP C 3 136 ? -139.587 -196.074 279.123 1.00 157.14 ? 136 ASP H OD2 1 ATOM 6881 N N . THR C 3 137 ? -141.212 -191.137 279.785 1.00 157.18 ? 137 THR H N 1 ATOM 6882 C CA . THR C 3 137 ? -140.389 -189.942 279.679 1.00 157.07 ? 137 THR H CA 1 ATOM 6883 C C . THR C 3 137 ? -138.909 -190.296 279.842 1.00 157.46 ? 137 THR H C 1 ATOM 6884 O O . THR C 3 137 ? -138.604 -191.180 280.645 1.00 157.84 ? 137 THR H O 1 ATOM 6885 C CB . THR C 3 137 ? -140.822 -188.916 280.775 1.00 155.21 ? 137 THR H CB 1 ATOM 6886 O OG1 . THR C 3 137 ? -141.982 -188.188 280.347 1.00 149.93 ? 137 THR H OG1 1 ATOM 6887 C CG2 . THR C 3 137 ? -139.713 -187.946 281.109 1.00 152.86 ? 137 THR H CG2 1 ATOM 6888 N N . THR C 3 138 ? -137.970 -189.694 279.098 1.00 155.11 ? 138 THR H N 1 ATOM 6889 C CA . THR C 3 138 ? -138.105 -188.935 277.841 1.00 154.23 ? 138 THR H CA 1 ATOM 6890 C C . THR C 3 138 ? -136.642 -188.863 277.328 1.00 150.99 ? 138 THR H C 1 ATOM 6891 O O . THR C 3 138 ? -135.791 -189.565 277.878 1.00 147.64 ? 138 THR H O 1 ATOM 6892 C CB . THR C 3 138 ? -138.734 -187.508 277.993 1.00 149.75 ? 138 THR H CB 1 ATOM 6893 O OG1 . THR C 3 138 ? -138.201 -186.822 279.136 1.00 152.70 ? 138 THR H OG1 1 ATOM 6894 C CG2 . THR C 3 138 ? -140.262 -187.535 278.022 1.00 148.72 ? 138 THR H CG2 1 ATOM 6895 N N . GLY C 3 139 ? -136.307 -188.052 276.317 1.00 143.76 ? 139 GLY H N 1 ATOM 6896 C CA . GLY C 3 139 ? -137.192 -187.120 275.643 1.00 137.69 ? 139 GLY H CA 1 ATOM 6897 C C . GLY C 3 139 ? -136.982 -185.681 276.091 1.00 135.14 ? 139 GLY H C 1 ATOM 6898 O O . GLY C 3 139 ? -137.590 -185.222 277.058 1.00 130.80 ? 139 GLY H O 1 ATOM 6899 N N . SER C 3 140 ? -136.132 -184.947 275.381 1.00 136.78 ? 140 SER H N 1 ATOM 6900 C CA . SER C 3 140 ? -135.977 -183.522 275.664 1.00 134.90 ? 140 SER H CA 1 ATOM 6901 C C . SER C 3 140 ? -137.321 -182.832 275.415 1.00 132.31 ? 140 SER H C 1 ATOM 6902 O O . SER C 3 140 ? -137.628 -181.784 275.994 1.00 129.93 ? 140 SER H O 1 ATOM 6903 C CB . SER C 3 140 ? -134.866 -182.897 274.806 1.00 133.05 ? 140 SER H CB 1 ATOM 6904 O OG . SER C 3 140 ? -135.190 -182.917 273.428 1.00 132.80 ? 140 SER H OG 1 ATOM 6905 N N . SER C 3 141 ? -138.121 -183.457 274.554 1.00 129.06 ? 141 SER H N 1 ATOM 6906 C CA . SER C 3 141 ? -139.429 -182.945 274.180 1.00 125.00 ? 141 SER H CA 1 ATOM 6907 C C . SER C 3 141 ? -140.447 -184.082 274.101 1.00 120.62 ? 141 SER H C 1 ATOM 6908 O O . SER C 3 141 ? -140.077 -185.258 274.137 1.00 118.20 ? 141 SER H O 1 ATOM 6909 C CB . SER C 3 141 ? -139.341 -182.210 272.841 1.00 119.79 ? 141 SER H CB 1 ATOM 6910 O OG . SER C 3 141 ? -140.394 -181.272 272.693 1.00 111.90 ? 141 SER H OG 1 ATOM 6911 N N . VAL C 3 142 ? -141.727 -183.723 274.010 1.00 118.39 ? 142 VAL H N 1 ATOM 6912 C CA . VAL C 3 142 ? -142.802 -184.700 273.816 1.00 117.26 ? 142 VAL H CA 1 ATOM 6913 C C . VAL C 3 142 ? -143.692 -184.322 272.612 1.00 112.12 ? 142 VAL H C 1 ATOM 6914 O O . VAL C 3 142 ? -143.809 -183.141 272.246 1.00 106.61 ? 142 VAL H O 1 ATOM 6915 C CB . VAL C 3 142 ? -143.680 -184.833 275.082 1.00 115.77 ? 142 VAL H CB 1 ATOM 6916 C CG1 . VAL C 3 142 ? -144.254 -183.476 275.482 1.00 116.94 ? 142 VAL H CG1 1 ATOM 6917 C CG2 . VAL C 3 142 ? -144.802 -185.846 274.863 1.00 107.38 ? 142 VAL H CG2 1 ATOM 6918 N N . THR C 3 143 ? -144.304 -185.327 271.988 1.00 109.72 ? 143 THR H N 1 ATOM 6919 C CA . THR C 3 143 ? -145.224 -185.084 270.880 1.00 105.56 ? 143 THR H CA 1 ATOM 6920 C C . THR C 3 143 ? -146.671 -185.384 271.258 1.00 98.99 ? 143 THR H C 1 ATOM 6921 O O . THR C 3 143 ? -146.987 -186.460 271.776 1.00 97.51 ? 143 THR H O 1 ATOM 6922 C CB . THR C 3 143 ? -144.864 -185.925 269.642 1.00 101.15 ? 143 THR H CB 1 ATOM 6923 O OG1 . THR C 3 143 ? -143.482 -185.752 269.324 1.00 104.72 ? 143 THR H OG1 1 ATOM 6924 C CG2 . THR C 3 143 ? -145.689 -185.475 268.464 1.00 101.64 ? 143 THR H CG2 1 ATOM 6925 N N . LEU C 3 144 ? -147.540 -184.416 270.990 1.00 98.21 ? 144 LEU H N 1 ATOM 6926 C CA . LEU C 3 144 ? -148.977 -184.577 271.178 1.00 104.63 ? 144 LEU H CA 1 ATOM 6927 C C . LEU C 3 144 ? -149.667 -184.632 269.820 1.00 103.01 ? 144 LEU H C 1 ATOM 6928 O O . LEU C 3 144 ? -149.084 -184.241 268.806 1.00 98.15 ? 144 LEU H O 1 ATOM 6929 C CB . LEU C 3 144 ? -149.542 -183.436 272.030 1.00 106.33 ? 144 LEU H CB 1 ATOM 6930 C CG . LEU C 3 144 ? -149.604 -183.672 273.545 1.00 102.92 ? 144 LEU H CG 1 ATOM 6931 C CD1 . LEU C 3 144 ? -148.280 -184.177 274.096 1.00 102.01 ? 144 LEU H CD1 1 ATOM 6932 C CD2 . LEU C 3 144 ? -150.035 -182.392 274.243 1.00 103.93 ? 144 LEU H CD2 1 ATOM 6933 N N . GLY C 3 145 ? -150.903 -185.122 269.789 1.00 98.69 ? 145 GLY H N 1 ATOM 6934 C CA . GLY C 3 145 ? -151.603 -185.228 268.523 1.00 97.24 ? 145 GLY H CA 1 ATOM 6935 C C . GLY C 3 145 ? -153.104 -185.031 268.560 1.00 94.77 ? 145 GLY H C 1 ATOM 6936 O O . GLY C 3 145 ? -153.736 -185.102 269.618 1.00 92.53 ? 145 GLY H O 1 ATOM 6937 N N . CYS C 3 146 ? -153.670 -184.806 267.377 1.00 94.64 ? 146 CYS H N 1 ATOM 6938 C CA . CYS C 3 146 ? -155.102 -184.593 267.221 1.00 90.06 ? 146 CYS H CA 1 ATOM 6939 C C . CYS C 3 146 ? -155.631 -185.283 265.965 1.00 89.08 ? 146 CYS H C 1 ATOM 6940 O O . CYS C 3 146 ? -155.025 -185.200 264.898 1.00 93.11 ? 146 CYS H O 1 ATOM 6941 C CB . CYS C 3 146 ? -155.406 -183.103 267.159 1.00 90.01 ? 146 CYS H CB 1 ATOM 6942 S SG . CYS C 3 146 ? -157.149 -182.727 267.258 1.00 100.88 ? 146 CYS H SG 1 ATOM 6943 N N . LEU C 3 147 ? -156.774 -185.948 266.088 1.00 85.50 ? 147 LEU H N 1 ATOM 6944 C CA . LEU C 3 147 ? -157.324 -186.726 264.987 1.00 80.46 ? 147 LEU H CA 1 ATOM 6945 C C . LEU C 3 147 ? -158.677 -186.178 264.562 1.00 84.73 ? 147 LEU H C 1 ATOM 6946 O O . LEU C 3 147 ? -159.653 -186.289 265.303 1.00 88.29 ? 147 LEU H O 1 ATOM 6947 C CB . LEU C 3 147 ? -157.456 -188.195 265.389 1.00 82.03 ? 147 LEU H CB 1 ATOM 6948 C CG . LEU C 3 147 ? -157.994 -189.162 264.338 1.00 82.27 ? 147 LEU H CG 1 ATOM 6949 C CD1 . LEU C 3 147 ? -157.075 -189.153 263.132 1.00 83.15 ? 147 LEU H CD1 1 ATOM 6950 C CD2 . LEU C 3 147 ? -158.136 -190.567 264.899 1.00 75.46 ? 147 LEU H CD2 1 ATOM 6951 N N . VAL C 3 148 ? -158.728 -185.571 263.379 1.00 81.52 ? 148 VAL H N 1 ATOM 6952 C CA . VAL C 3 148 ? -159.978 -185.061 262.824 1.00 78.46 ? 148 VAL H CA 1 ATOM 6953 C C . VAL C 3 148 ? -160.508 -186.038 261.778 1.00 80.21 ? 148 VAL H C 1 ATOM 6954 O O . VAL C 3 148 ? -160.117 -185.973 260.608 1.00 82.16 ? 148 VAL H O 1 ATOM 6955 C CB . VAL C 3 148 ? -159.785 -183.681 262.180 1.00 77.65 ? 148 VAL H CB 1 ATOM 6956 C CG1 . VAL C 3 148 ? -161.131 -183.040 261.880 1.00 77.37 ? 148 VAL H CG1 1 ATOM 6957 C CG2 . VAL C 3 148 ? -158.949 -182.795 263.082 1.00 81.95 ? 148 VAL H CG2 1 ATOM 6958 N N . LYS C 3 149 ? -161.388 -186.944 262.195 1.00 78.19 ? 149 LYS H N 1 ATOM 6959 C CA . LYS C 3 149 ? -161.787 -188.070 261.345 1.00 78.29 ? 149 LYS H CA 1 ATOM 6960 C C . LYS C 3 149 ? -163.227 -187.995 260.844 1.00 76.82 ? 149 LYS H C 1 ATOM 6961 O O . LYS C 3 149 ? -164.120 -187.555 261.561 1.00 80.94 ? 149 LYS H O 1 ATOM 6962 C CB . LYS C 3 149 ? -161.578 -189.381 262.110 1.00 74.60 ? 149 LYS H CB 1 ATOM 6963 C CG . LYS C 3 149 ? -161.820 -190.638 261.315 1.00 77.56 ? 149 LYS H CG 1 ATOM 6964 C CD . LYS C 3 149 ? -161.324 -191.860 262.081 1.00 79.89 ? 149 LYS H CD 1 ATOM 6965 C CE . LYS C 3 149 ? -161.841 -193.148 261.451 1.00 78.64 ? 149 LYS H CE 1 ATOM 6966 N NZ . LYS C 3 149 ? -161.503 -193.233 260.010 1.00 84.68 ? 149 LYS H NZ 1 ATOM 6967 N N . GLY C 3 150 ? -163.447 -188.438 259.611 1.00 74.84 ? 150 GLY H N 1 ATOM 6968 C CA . GLY C 3 150 ? -164.793 -188.680 259.118 1.00 69.11 ? 150 GLY H CA 1 ATOM 6969 C C . GLY C 3 150 ? -165.633 -187.490 258.707 1.00 78.37 ? 150 GLY H C 1 ATOM 6970 O O . GLY C 3 150 ? -166.854 -187.518 258.875 1.00 79.11 ? 150 GLY H O 1 ATOM 6971 N N . TYR C 3 151 ? -164.995 -186.433 258.198 1.00 80.07 ? 151 TYR H N 1 ATOM 6972 C CA . TYR C 3 151 ? -165.734 -185.246 257.765 1.00 72.78 ? 151 TYR H CA 1 ATOM 6973 C C . TYR C 3 151 ? -165.833 -185.089 256.255 1.00 72.45 ? 151 TYR H C 1 ATOM 6974 O O . TYR C 3 151 ? -165.058 -185.678 255.501 1.00 75.94 ? 151 TYR H O 1 ATOM 6975 C CB . TYR C 3 151 ? -165.116 -183.980 258.362 1.00 75.23 ? 151 TYR H CB 1 ATOM 6976 C CG . TYR C 3 151 ? -163.755 -183.587 257.834 1.00 76.60 ? 151 TYR H CG 1 ATOM 6977 C CD1 . TYR C 3 151 ? -163.628 -182.689 256.774 1.00 74.01 ? 151 TYR H CD1 1 ATOM 6978 C CD2 . TYR C 3 151 ? -162.595 -184.076 258.420 1.00 74.56 ? 151 TYR H CD2 1 ATOM 6979 C CE1 . TYR C 3 151 ? -162.388 -182.313 256.302 1.00 72.44 ? 151 TYR H CE1 1 ATOM 6980 C CE2 . TYR C 3 151 ? -161.354 -183.704 257.954 1.00 73.46 ? 151 TYR H CE2 1 ATOM 6981 C CZ . TYR C 3 151 ? -161.252 -182.827 256.894 1.00 78.27 ? 151 TYR H CZ 1 ATOM 6982 O OH . TYR C 3 151 ? -160.002 -182.454 256.436 1.00 78.32 ? 151 TYR H OH 1 ATOM 6983 N N . PHE C 3 152 ? -166.816 -184.303 255.828 1.00 73.54 ? 152 PHE H N 1 ATOM 6984 C CA . PHE C 3 152 ? -166.985 -183.910 254.431 1.00 71.89 ? 152 PHE H CA 1 ATOM 6985 C C . PHE C 3 152 ? -167.923 -182.707 254.391 1.00 77.07 ? 152 PHE H C 1 ATOM 6986 O O . PHE C 3 152 ? -168.843 -182.622 255.214 1.00 77.08 ? 152 PHE H O 1 ATOM 6987 C CB . PHE C 3 152 ? -167.551 -185.070 253.606 1.00 70.38 ? 152 PHE H CB 1 ATOM 6988 C CG . PHE C 3 152 ? -167.666 -184.785 252.138 1.00 72.89 ? 152 PHE H CG 1 ATOM 6989 C CD1 . PHE C 3 152 ? -166.669 -185.184 251.260 1.00 72.27 ? 152 PHE H CD1 1 ATOM 6990 C CD2 . PHE C 3 152 ? -168.778 -184.136 251.629 1.00 72.23 ? 152 PHE H CD2 1 ATOM 6991 C CE1 . PHE C 3 152 ? -166.781 -184.927 249.906 1.00 69.68 ? 152 PHE H CE1 1 ATOM 6992 C CE2 . PHE C 3 152 ? -168.895 -183.879 250.271 1.00 71.68 ? 152 PHE H CE2 1 ATOM 6993 C CZ . PHE C 3 152 ? -167.899 -184.272 249.409 1.00 67.20 ? 152 PHE H CZ 1 ATOM 6994 N N . PRO C 3 153 ? -167.700 -181.766 253.455 1.00 80.42 ? 153 PRO H N 1 ATOM 6995 C CA . PRO C 3 153 ? -166.586 -181.705 252.506 1.00 75.89 ? 153 PRO H CA 1 ATOM 6996 C C . PRO C 3 153 ? -165.390 -181.024 253.125 1.00 73.08 ? 153 PRO H C 1 ATOM 6997 O O . PRO C 3 153 ? -165.485 -180.635 254.281 1.00 72.99 ? 153 PRO H O 1 ATOM 6998 C CB . PRO C 3 153 ? -167.153 -180.864 251.366 1.00 69.27 ? 153 PRO H CB 1 ATOM 6999 C CG . PRO C 3 153 ? -168.022 -179.885 252.074 1.00 73.82 ? 153 PRO H CG 1 ATOM 7000 C CD . PRO C 3 153 ? -168.637 -180.644 253.250 1.00 77.47 ? 153 PRO H CD 1 ATOM 7001 N N . GLU C 3 154 ? -164.302 -180.872 252.372 1.00 75.42 ? 154 GLU H N 1 ATOM 7002 C CA . GLU C 3 154 ? -163.195 -180.025 252.801 1.00 77.82 ? 154 GLU H CA 1 ATOM 7003 C C . GLU C 3 154 ? -163.725 -178.589 252.748 1.00 77.67 ? 154 GLU H C 1 ATOM 7004 O O . GLU C 3 154 ? -164.675 -178.330 252.013 1.00 77.86 ? 154 GLU H O 1 ATOM 7005 C CB . GLU C 3 154 ? -161.973 -180.221 251.900 1.00 78.94 ? 154 GLU H CB 1 ATOM 7006 C CG . GLU C 3 154 ? -160.674 -179.619 252.434 1.00 88.21 ? 154 GLU H CG 1 ATOM 7007 C CD . GLU C 3 154 ? -160.091 -180.427 253.577 1.00 87.69 ? 154 GLU H CD 1 ATOM 7008 O OE1 . GLU C 3 154 ? -160.238 -181.666 253.526 1.00 88.70 ? 154 GLU H OE1 1 ATOM 7009 O OE2 . GLU C 3 154 ? -159.503 -179.834 254.520 1.00 88.20 ? 154 GLU H OE2 1 ATOM 7010 N N . PRO C 3 155 ? -163.167 -177.649 253.538 1.00 75.40 ? 155 PRO H N 1 ATOM 7011 C CA . PRO C 3 155 ? -162.044 -177.554 254.480 1.00 79.24 ? 155 PRO H CA 1 ATOM 7012 C C . PRO C 3 155 ? -162.409 -177.636 255.958 1.00 81.35 ? 155 PRO H C 1 ATOM 7013 O O . PRO C 3 155 ? -163.559 -177.365 256.318 1.00 83.70 ? 155 PRO H O 1 ATOM 7014 C CB . PRO C 3 155 ? -161.511 -176.161 254.196 1.00 71.79 ? 155 PRO H CB 1 ATOM 7015 C CG . PRO C 3 155 ? -162.779 -175.380 254.012 1.00 68.61 ? 155 PRO H CG 1 ATOM 7016 C CD . PRO C 3 155 ? -163.752 -176.315 253.311 1.00 71.57 ? 155 PRO H CD 1 ATOM 7017 N N . VAL C 3 156 ? -161.429 -177.975 256.798 1.00 79.95 ? 156 VAL H N 1 ATOM 7018 C CA . VAL C 3 156 ? -161.548 -177.767 258.237 1.00 77.34 ? 156 VAL H CA 1 ATOM 7019 C C . VAL C 3 156 ? -160.368 -176.941 258.718 1.00 85.78 ? 156 VAL H C 1 ATOM 7020 O O . VAL C 3 156 ? -159.295 -176.963 258.113 1.00 91.63 ? 156 VAL H O 1 ATOM 7021 C CB . VAL C 3 156 ? -161.606 -179.074 259.042 1.00 76.61 ? 156 VAL H CB 1 ATOM 7022 C CG1 . VAL C 3 156 ? -162.721 -179.963 258.524 1.00 79.72 ? 156 VAL H CG1 1 ATOM 7023 C CG2 . VAL C 3 156 ? -160.283 -179.782 259.022 1.00 76.68 ? 156 VAL H CG2 1 ATOM 7024 N N . THR C 3 157 ? -160.578 -176.201 259.802 1.00 84.46 ? 157 THR H N 1 ATOM 7025 C CA . THR C 3 157 ? -159.556 -175.344 260.380 1.00 81.90 ? 157 THR H CA 1 ATOM 7026 C C . THR C 3 157 ? -159.032 -175.942 261.675 1.00 88.32 ? 157 THR H C 1 ATOM 7027 O O . THR C 3 157 ? -159.755 -176.007 262.677 1.00 91.84 ? 157 THR H O 1 ATOM 7028 C CB . THR C 3 157 ? -160.105 -173.927 260.650 1.00 85.17 ? 157 THR H CB 1 ATOM 7029 O OG1 . THR C 3 157 ? -160.066 -173.162 259.440 1.00 83.15 ? 157 THR H OG1 1 ATOM 7030 C CG2 . THR C 3 157 ? -159.284 -173.215 261.718 1.00 83.26 ? 157 THR H CG2 1 ATOM 7031 N N . LEU C 3 158 ? -157.779 -176.388 261.655 1.00 88.96 ? 158 LEU H N 1 ATOM 7032 C CA . LEU C 3 158 ? -157.127 -176.848 262.875 1.00 85.50 ? 158 LEU H CA 1 ATOM 7033 C C . LEU C 3 158 ? -156.047 -175.866 263.325 1.00 88.62 ? 158 LEU H C 1 ATOM 7034 O O . LEU C 3 158 ? -155.316 -175.307 262.507 1.00 91.02 ? 158 LEU H O 1 ATOM 7035 C CB . LEU C 3 158 ? -156.534 -178.243 262.676 1.00 82.99 ? 158 LEU H CB 1 ATOM 7036 C CG . LEU C 3 158 ? -156.273 -178.993 263.985 1.00 93.23 ? 158 LEU H CG 1 ATOM 7037 C CD1 . LEU C 3 158 ? -156.546 -180.486 263.819 1.00 93.25 ? 158 LEU H CD1 1 ATOM 7038 C CD2 . LEU C 3 158 ? -154.856 -178.750 264.492 1.00 89.64 ? 158 LEU H CD2 1 ATOM 7039 N N . THR C 3 159 ? -155.973 -175.643 264.634 1.00 93.57 ? 159 THR H N 1 ATOM 7040 C CA . THR C 3 159 ? -154.903 -174.855 265.245 1.00 95.34 ? 159 THR H CA 1 ATOM 7041 C C . THR C 3 159 ? -154.633 -175.448 266.614 1.00 94.56 ? 159 THR H C 1 ATOM 7042 O O . THR C 3 159 ? -155.291 -176.405 267.017 1.00 97.42 ? 159 THR H O 1 ATOM 7043 C CB . THR C 3 159 ? -155.240 -173.347 265.385 1.00 91.26 ? 159 THR H CB 1 ATOM 7044 O OG1 . THR C 3 159 ? -156.484 -173.190 266.075 1.00 90.65 ? 159 THR H OG1 1 ATOM 7045 C CG2 . THR C 3 159 ? -155.322 -172.667 264.022 1.00 86.10 ? 159 THR H CG2 1 ATOM 7046 N N . TRP C 3 160 ? -153.643 -174.911 267.313 1.00 97.89 ? 160 TRP H N 1 ATOM 7047 C CA . TRP C 3 160 ? -153.368 -175.360 268.668 1.00 98.13 ? 160 TRP H CA 1 ATOM 7048 C C . TRP C 3 160 ? -153.361 -174.184 269.619 1.00 103.82 ? 160 TRP H C 1 ATOM 7049 O O . TRP C 3 160 ? -152.743 -173.157 269.323 1.00 105.61 ? 160 TRP H O 1 ATOM 7050 C CB . TRP C 3 160 ? -152.037 -176.096 268.730 1.00 94.03 ? 160 TRP H CB 1 ATOM 7051 C CG . TRP C 3 160 ? -152.077 -177.414 268.037 1.00 96.60 ? 160 TRP H CG 1 ATOM 7052 C CD1 . TRP C 3 160 ? -151.812 -177.654 266.721 1.00 94.55 ? 160 TRP H CD1 1 ATOM 7053 C CD2 . TRP C 3 160 ? -152.406 -178.680 268.619 1.00 92.81 ? 160 TRP H CD2 1 ATOM 7054 N NE1 . TRP C 3 160 ? -151.951 -178.991 266.449 1.00 94.89 ? 160 TRP H NE1 1 ATOM 7055 C CE2 . TRP C 3 160 ? -152.316 -179.645 267.596 1.00 94.39 ? 160 TRP H CE2 1 ATOM 7056 C CE3 . TRP C 3 160 ? -152.768 -179.091 269.903 1.00 94.64 ? 160 TRP H CE3 1 ATOM 7057 C CZ2 . TRP C 3 160 ? -152.572 -181.001 267.819 1.00 94.71 ? 160 TRP H CZ2 1 ATOM 7058 C CZ3 . TRP C 3 160 ? -153.028 -180.435 270.123 1.00 99.78 ? 160 TRP H CZ3 1 ATOM 7059 C CH2 . TRP C 3 160 ? -152.925 -181.376 269.085 1.00 97.49 ? 160 TRP H CH2 1 ATOM 7060 N N . ASN C 3 161 ? -154.045 -174.337 270.754 1.00 103.39 ? 161 ASN H N 1 ATOM 7061 C CA . ASN C 3 161 ? -154.179 -173.257 271.731 1.00 100.24 ? 161 ASN H CA 1 ATOM 7062 C C . ASN C 3 161 ? -154.569 -171.959 271.034 1.00 102.26 ? 161 ASN H C 1 ATOM 7063 O O . ASN C 3 161 ? -153.993 -170.905 271.291 1.00 105.98 ? 161 ASN H O 1 ATOM 7064 C CB . ASN C 3 161 ? -152.885 -173.066 272.523 1.00 92.68 ? 161 ASN H CB 1 ATOM 7065 C CG . ASN C 3 161 ? -152.679 -174.138 273.574 1.00 101.84 ? 161 ASN H CG 1 ATOM 7066 O OD1 . ASN C 3 161 ? -153.607 -174.870 273.925 1.00 101.60 ? 161 ASN H OD1 1 ATOM 7067 N ND2 . ASN C 3 161 ? -151.456 -174.231 274.092 1.00 107.23 ? 161 ASN H ND2 1 ATOM 7068 N N . SER C 3 162 ? -155.523 -172.068 270.116 1.00 101.81 ? 162 SER H N 1 ATOM 7069 C CA . SER C 3 162 ? -156.032 -170.935 269.346 1.00 102.35 ? 162 SER H CA 1 ATOM 7070 C C . SER C 3 162 ? -154.939 -170.177 268.579 1.00 102.78 ? 162 SER H C 1 ATOM 7071 O O . SER C 3 162 ? -155.029 -168.965 268.377 1.00 103.45 ? 162 SER H O 1 ATOM 7072 C CB . SER C 3 162 ? -156.795 -169.990 270.271 1.00 98.78 ? 162 SER H CB 1 ATOM 7073 O OG . SER C 3 162 ? -157.686 -170.729 271.092 1.00 96.98 ? 162 SER H OG 1 ATOM 7074 N N . GLY C 3 163 ? -153.927 -170.911 268.126 1.00 100.13 ? 163 GLY H N 1 ATOM 7075 C CA . GLY C 3 163 ? -152.901 -170.352 267.265 1.00 103.58 ? 163 GLY H CA 1 ATOM 7076 C C . GLY C 3 163 ? -151.692 -169.778 267.982 1.00 108.66 ? 163 GLY H C 1 ATOM 7077 O O . GLY C 3 163 ? -150.709 -169.393 267.344 1.00 107.77 ? 163 GLY H O 1 ATOM 7078 N N . SER C 3 164 ? -151.746 -169.733 269.309 1.00 110.47 ? 164 SER H N 1 ATOM 7079 C CA . SER C 3 164 ? -150.612 -169.245 270.082 1.00 108.93 ? 164 SER H CA 1 ATOM 7080 C C . SER C 3 164 ? -149.421 -170.158 269.844 1.00 107.57 ? 164 SER H C 1 ATOM 7081 O O . SER C 3 164 ? -148.268 -169.721 269.829 1.00 106.13 ? 164 SER H O 1 ATOM 7082 C CB . SER C 3 164 ? -150.951 -169.195 271.574 1.00 105.77 ? 164 SER H CB 1 ATOM 7083 O OG . SER C 3 164 ? -152.160 -168.497 271.804 1.00 111.78 ? 164 SER H OG 1 ATOM 7084 N N . LEU C 3 165 ? -149.731 -171.428 269.616 1.00 102.63 ? 165 LEU H N 1 ATOM 7085 C CA . LEU C 3 165 ? -148.733 -172.476 269.531 1.00 100.23 ? 165 LEU H CA 1 ATOM 7086 C C . LEU C 3 165 ? -148.505 -172.885 268.075 1.00 100.29 ? 165 LEU H C 1 ATOM 7087 O O . LEU C 3 165 ? -149.089 -173.854 267.610 1.00 104.63 ? 165 LEU H O 1 ATOM 7088 C CB . LEU C 3 165 ? -149.190 -173.665 270.385 1.00 91.65 ? 165 LEU H CB 1 ATOM 7089 C CG . LEU C 3 165 ? -148.304 -174.899 270.487 1.00 85.78 ? 165 LEU H CG 1 ATOM 7090 C CD1 . LEU C 3 165 ? -146.875 -174.482 270.709 1.00 89.73 ? 165 LEU H CD1 1 ATOM 7091 C CD2 . LEU C 3 165 ? -148.795 -175.803 271.608 1.00 87.43 ? 165 LEU H CD2 1 ATOM 7092 N N . SER C 3 166 ? -147.687 -172.131 267.346 1.00 102.24 ? 166 SER H N 1 ATOM 7093 C CA . SER C 3 166 ? -147.460 -172.432 265.933 1.00 102.27 ? 166 SER H CA 1 ATOM 7094 C C . SER C 3 166 ? -146.147 -173.183 265.676 1.00 106.78 ? 166 SER H C 1 ATOM 7095 O O . SER C 3 166 ? -146.038 -173.927 264.701 1.00 109.37 ? 166 SER H O 1 ATOM 7096 C CB . SER C 3 166 ? -147.496 -171.145 265.098 1.00 107.06 ? 166 SER H CB 1 ATOM 7097 O OG . SER C 3 166 ? -146.424 -170.272 265.418 1.00 114.64 ? 166 SER H OG 1 ATOM 7098 N N . SER C 3 167 ? -145.151 -172.988 266.536 1.00 105.17 ? 167 SER H N 1 ATOM 7099 C CA . SER C 3 167 ? -143.890 -173.712 266.407 1.00 102.64 ? 167 SER H CA 1 ATOM 7100 C C . SER C 3 167 ? -144.068 -175.203 266.698 1.00 104.73 ? 167 SER H C 1 ATOM 7101 O O . SER C 3 167 ? -144.821 -175.585 267.600 1.00 103.10 ? 167 SER H O 1 ATOM 7102 C CB . SER C 3 167 ? -142.828 -173.122 267.342 1.00 108.33 ? 167 SER H CB 1 ATOM 7103 O OG . SER C 3 167 ? -142.343 -171.876 266.862 1.00 115.95 ? 167 SER H OG 1 ATOM 7104 N N . GLY C 3 168 ? -143.377 -176.042 265.927 1.00 103.76 ? 168 GLY H N 1 ATOM 7105 C CA . GLY C 3 168 ? -143.355 -177.479 266.166 1.00 102.42 ? 168 GLY H CA 1 ATOM 7106 C C . GLY C 3 168 ? -144.594 -178.221 265.683 1.00 100.10 ? 168 GLY H C 1 ATOM 7107 O O . GLY C 3 168 ? -144.773 -179.411 265.960 1.00 103.04 ? 168 GLY H O 1 ATOM 7108 N N . VAL C 3 169 ? -145.451 -177.511 264.956 1.00 99.49 ? 169 VAL H N 1 ATOM 7109 C CA . VAL C 3 169 ? -146.718 -178.056 264.489 1.00 96.75 ? 169 VAL H CA 1 ATOM 7110 C C . VAL C 3 169 ? -146.639 -178.611 263.059 1.00 94.92 ? 169 VAL H C 1 ATOM 7111 O O . VAL C 3 169 ? -146.161 -177.943 262.131 1.00 90.98 ? 169 VAL H O 1 ATOM 7112 C CB . VAL C 3 169 ? -147.831 -176.980 264.563 1.00 99.69 ? 169 VAL H CB 1 ATOM 7113 C CG1 . VAL C 3 169 ? -149.110 -177.464 263.897 1.00 91.69 ? 169 VAL H CG1 1 ATOM 7114 C CG2 . VAL C 3 169 ? -148.088 -176.604 266.007 1.00 96.55 ? 169 VAL H CG2 1 ATOM 7115 N N . HIS C 3 170 ? -147.120 -179.843 262.905 1.00 90.42 ? 170 HIS H N 1 ATOM 7116 C CA . HIS C 3 170 ? -147.270 -180.491 261.604 1.00 87.15 ? 170 HIS H CA 1 ATOM 7117 C C . HIS C 3 170 ? -148.730 -180.872 261.372 1.00 84.09 ? 170 HIS H C 1 ATOM 7118 O O . HIS C 3 170 ? -149.230 -181.807 262.005 1.00 85.55 ? 170 HIS H O 1 ATOM 7119 C CB . HIS C 3 170 ? -146.398 -181.743 261.514 1.00 83.85 ? 170 HIS H CB 1 ATOM 7120 C CG . HIS C 3 170 ? -144.944 -181.457 261.338 1.00 85.17 ? 170 HIS H CG 1 ATOM 7121 N ND1 . HIS C 3 170 ? -144.440 -180.818 260.224 1.00 88.83 ? 170 HIS H ND1 1 ATOM 7122 C CD2 . HIS C 3 170 ? -143.880 -181.737 262.126 1.00 91.45 ? 170 HIS H CD2 1 ATOM 7123 C CE1 . HIS C 3 170 ? -143.127 -180.715 260.337 1.00 93.21 ? 170 HIS H CE1 1 ATOM 7124 N NE2 . HIS C 3 170 ? -142.761 -181.263 261.483 1.00 93.43 ? 170 HIS H NE2 1 ATOM 7125 N N . THR C 3 171 ? -149.421 -180.160 260.486 1.00 75.49 ? 171 THR H N 1 ATOM 7126 C CA . THR C 3 171 ? -150.816 -180.495 260.206 1.00 77.31 ? 171 THR H CA 1 ATOM 7127 C C . THR C 3 171 ? -150.982 -181.096 258.820 1.00 76.71 ? 171 THR H C 1 ATOM 7128 O O . THR C 3 171 ? -150.853 -180.421 257.798 1.00 76.49 ? 171 THR H O 1 ATOM 7129 C CB . THR C 3 171 ? -151.748 -179.294 260.326 1.00 80.81 ? 171 THR H CB 1 ATOM 7130 O OG1 . THR C 3 171 ? -151.785 -178.861 261.689 1.00 86.86 ? 171 THR H OG1 1 ATOM 7131 C CG2 . THR C 3 171 ? -153.147 -179.710 259.910 1.00 76.59 ? 171 THR H CG2 1 ATOM 7132 N N . PHE C 3 172 ? -151.291 -182.381 258.806 1.00 78.45 ? 172 PHE H N 1 ATOM 7133 C CA . PHE C 3 172 ? -151.292 -183.157 257.587 1.00 73.81 ? 172 PHE H CA 1 ATOM 7134 C C . PHE C 3 172 ? -152.496 -182.899 256.705 1.00 75.79 ? 172 PHE H C 1 ATOM 7135 O O . PHE C 3 172 ? -153.615 -182.747 257.185 1.00 77.90 ? 172 PHE H O 1 ATOM 7136 C CB . PHE C 3 172 ? -151.181 -184.630 257.956 1.00 75.77 ? 172 PHE H CB 1 ATOM 7137 C CG . PHE C 3 172 ? -149.929 -184.940 258.717 1.00 74.25 ? 172 PHE H CG 1 ATOM 7138 C CD1 . PHE C 3 172 ? -148.734 -185.163 258.044 1.00 74.07 ? 172 PHE H CD1 1 ATOM 7139 C CD2 . PHE C 3 172 ? -149.931 -184.954 260.100 1.00 76.02 ? 172 PHE H CD2 1 ATOM 7140 C CE1 . PHE C 3 172 ? -147.571 -185.423 258.737 1.00 79.01 ? 172 PHE H CE1 1 ATOM 7141 C CE2 . PHE C 3 172 ? -148.770 -185.219 260.802 1.00 78.08 ? 172 PHE H CE2 1 ATOM 7142 C CZ . PHE C 3 172 ? -147.590 -185.452 260.126 1.00 77.94 ? 172 PHE H CZ 1 ATOM 7143 N N . PRO C 3 173 ? -152.254 -182.810 255.394 1.00 78.16 ? 173 PRO H N 1 ATOM 7144 C CA . PRO C 3 173 ? -153.385 -182.570 254.500 1.00 73.94 ? 173 PRO H CA 1 ATOM 7145 C C . PRO C 3 173 ? -154.373 -183.726 254.565 1.00 73.93 ? 173 PRO H C 1 ATOM 7146 O O . PRO C 3 173 ? -153.983 -184.868 254.769 1.00 76.52 ? 173 PRO H O 1 ATOM 7147 C CB . PRO C 3 173 ? -152.731 -182.445 253.119 1.00 65.62 ? 173 PRO H CB 1 ATOM 7148 C CG . PRO C 3 173 ? -151.345 -182.973 253.278 1.00 67.34 ? 173 PRO H CG 1 ATOM 7149 C CD . PRO C 3 173 ? -150.959 -182.798 254.696 1.00 69.54 ? 173 PRO H CD 1 ATOM 7150 N N . ALA C 3 174 ? -155.654 -183.420 254.424 1.00 75.03 ? 174 ALA H N 1 ATOM 7151 C CA . ALA C 3 174 ? -156.687 -184.437 254.543 1.00 74.57 ? 174 ALA H CA 1 ATOM 7152 C C . ALA C 3 174 ? -156.666 -185.397 253.357 1.00 78.01 ? 174 ALA H C 1 ATOM 7153 O O . ALA C 3 174 ? -156.171 -185.060 252.279 1.00 79.03 ? 174 ALA H O 1 ATOM 7154 C CB . ALA C 3 174 ? -158.045 -183.787 254.673 1.00 75.64 ? 174 ALA H CB 1 ATOM 7155 N N . VAL C 3 175 ? -157.180 -186.605 253.573 1.00 78.26 ? 175 VAL H N 1 ATOM 7156 C CA . VAL C 3 175 ? -157.219 -187.628 252.537 1.00 71.88 ? 175 VAL H CA 1 ATOM 7157 C C . VAL C 3 175 ? -158.584 -188.274 252.440 1.00 72.19 ? 175 VAL H C 1 ATOM 7158 O O . VAL C 3 175 ? -159.042 -188.887 253.391 1.00 71.42 ? 175 VAL H O 1 ATOM 7159 C CB . VAL C 3 175 ? -156.183 -188.716 252.796 1.00 72.81 ? 175 VAL H CB 1 ATOM 7160 C CG1 . VAL C 3 175 ? -156.196 -189.709 251.658 1.00 64.26 ? 175 VAL H CG1 1 ATOM 7161 C CG2 . VAL C 3 175 ? -154.803 -188.084 252.965 1.00 73.22 ? 175 VAL H CG2 1 ATOM 7162 N N . LEU C 3 176 ? -159.235 -188.126 251.286 1.00 82.82 ? 176 LEU H N 1 ATOM 7163 C CA . LEU C 3 176 ? -160.568 -188.705 251.064 1.00 74.66 ? 176 LEU H CA 1 ATOM 7164 C C . LEU C 3 176 ? -160.529 -190.226 251.033 1.00 77.83 ? 176 LEU H C 1 ATOM 7165 O O . LEU C 3 176 ? -159.681 -190.826 250.370 1.00 80.27 ? 176 LEU H O 1 ATOM 7166 C CB . LEU C 3 176 ? -161.169 -188.190 249.765 1.00 71.85 ? 176 LEU H CB 1 ATOM 7167 C CG . LEU C 3 176 ? -162.662 -188.368 249.512 1.00 72.21 ? 176 LEU H CG 1 ATOM 7168 C CD1 . LEU C 3 176 ? -163.465 -187.516 250.458 1.00 72.38 ? 176 LEU H CD1 1 ATOM 7169 C CD2 . LEU C 3 176 ? -162.965 -187.981 248.076 1.00 75.62 ? 176 LEU H CD2 1 ATOM 7170 N N . GLN C 3 177 ? -161.468 -190.851 251.727 1.00 78.66 ? 177 GLN H N 1 ATOM 7171 C CA . GLN C 3 177 ? -161.588 -192.300 251.702 1.00 73.60 ? 177 GLN H CA 1 ATOM 7172 C C . GLN C 3 177 ? -163.068 -192.690 251.884 1.00 76.99 ? 177 GLN H C 1 ATOM 7173 O O . GLN C 3 177 ? -163.665 -192.455 252.942 1.00 73.27 ? 177 GLN H O 1 ATOM 7174 C CB . GLN C 3 177 ? -160.692 -192.936 252.777 1.00 73.49 ? 177 GLN H CB 1 ATOM 7175 C CG . GLN C 3 177 ? -159.173 -192.844 252.508 1.00 74.40 ? 177 GLN H CG 1 ATOM 7176 C CD . GLN C 3 177 ? -158.346 -193.768 253.422 1.00 78.81 ? 177 GLN H CD 1 ATOM 7177 O OE1 . GLN C 3 177 ? -158.859 -194.308 254.400 1.00 78.59 ? 177 GLN H OE1 1 ATOM 7178 N NE2 . GLN C 3 177 ? -157.072 -193.956 253.094 1.00 74.86 ? 177 GLN H NE2 1 ATOM 7179 N N . SER C 3 178 ? -163.644 -193.274 250.832 1.00 82.67 ? 178 SER H N 1 ATOM 7180 C CA . SER C 3 178 ? -165.053 -193.658 250.794 1.00 75.12 ? 178 SER H CA 1 ATOM 7181 C C . SER C 3 178 ? -165.914 -192.476 251.237 1.00 79.03 ? 178 SER H C 1 ATOM 7182 O O . SER C 3 178 ? -166.728 -192.568 252.163 1.00 82.85 ? 178 SER H O 1 ATOM 7183 C CB . SER C 3 178 ? -165.319 -194.904 251.643 1.00 73.41 ? 178 SER H CB 1 ATOM 7184 O OG . SER C 3 178 ? -165.065 -194.658 253.011 1.00 88.22 ? 178 SER H OG 1 ATOM 7185 N N . ASP C 3 179 ? -165.693 -191.354 250.566 1.00 80.56 ? 179 ASP H N 1 ATOM 7186 C CA . ASP C 3 179 ? -166.504 -190.157 250.740 1.00 77.87 ? 179 ASP H CA 1 ATOM 7187 C C . ASP C 3 179 ? -166.407 -189.516 252.127 1.00 77.81 ? 179 ASP H C 1 ATOM 7188 O O . ASP C 3 179 ? -167.353 -188.860 252.576 1.00 76.84 ? 179 ASP H O 1 ATOM 7189 C CB . ASP C 3 179 ? -167.958 -190.481 250.419 1.00 73.53 ? 179 ASP H CB 1 ATOM 7190 C CG . ASP C 3 179 ? -168.195 -190.654 248.919 1.00 95.54 ? 179 ASP H CG 1 ATOM 7191 O OD1 . ASP C 3 179 ? -167.377 -190.129 248.118 1.00 98.29 ? 179 ASP H OD1 1 ATOM 7192 O OD2 . ASP C 3 179 ? -169.197 -191.305 248.538 1.00 101.63 ? 179 ASP H OD2 1 ATOM 7193 N N . LEU C 3 180 ? -165.254 -189.665 252.782 1.00 77.35 ? 180 LEU H N 1 ATOM 7194 C CA . LEU C 3 180 ? -165.010 -188.976 254.051 1.00 75.79 ? 180 LEU H CA 1 ATOM 7195 C C . LEU C 3 180 ? -163.543 -188.629 254.223 1.00 71.86 ? 180 LEU H C 1 ATOM 7196 O O . LEU C 3 180 ? -162.680 -189.500 254.142 1.00 72.09 ? 180 LEU H O 1 ATOM 7197 C CB . LEU C 3 180 ? -165.476 -189.820 255.240 1.00 79.67 ? 180 LEU H CB 1 ATOM 7198 C CG . LEU C 3 180 ? -166.968 -190.123 255.406 1.00 74.73 ? 180 LEU H CG 1 ATOM 7199 C CD1 . LEU C 3 180 ? -167.160 -191.029 256.595 1.00 65.88 ? 180 LEU H CD1 1 ATOM 7200 C CD2 . LEU C 3 180 ? -167.792 -188.854 255.545 1.00 63.25 ? 180 LEU H CD2 1 ATOM 7201 N N . TYR C 3 181 ? -163.258 -187.347 254.420 1.00 72.81 ? 181 TYR H N 1 ATOM 7202 C CA . TYR C 3 181 ? -161.899 -186.936 254.748 1.00 76.03 ? 181 TYR H CA 1 ATOM 7203 C C . TYR C 3 181 ? -161.528 -187.314 256.174 1.00 75.33 ? 181 TYR H C 1 ATOM 7204 O O . TYR C 3 181 ? -162.351 -187.233 257.090 1.00 74.08 ? 181 TYR H O 1 ATOM 7205 C CB . TYR C 3 181 ? -161.706 -185.436 254.561 1.00 72.10 ? 181 TYR H CB 1 ATOM 7206 C CG . TYR C 3 181 ? -161.863 -184.976 253.131 1.00 75.65 ? 181 TYR H CG 1 ATOM 7207 C CD1 . TYR C 3 181 ? -160.792 -185.002 252.240 1.00 69.77 ? 181 TYR H CD1 1 ATOM 7208 C CD2 . TYR C 3 181 ? -163.084 -184.498 252.676 1.00 75.49 ? 181 TYR H CD2 1 ATOM 7209 C CE1 . TYR C 3 181 ? -160.949 -184.575 250.938 1.00 73.70 ? 181 TYR H CE1 1 ATOM 7210 C CE2 . TYR C 3 181 ? -163.246 -184.070 251.386 1.00 77.30 ? 181 TYR H CE2 1 ATOM 7211 C CZ . TYR C 3 181 ? -162.187 -184.105 250.513 1.00 78.45 ? 181 TYR H CZ 1 ATOM 7212 O OH . TYR C 3 181 ? -162.397 -183.666 249.218 1.00 77.53 ? 181 TYR H OH 1 ATOM 7213 N N . THR C 3 182 ? -160.274 -187.708 256.347 1.00 74.58 ? 182 THR H N 1 ATOM 7214 C CA . THR C 3 182 ? -159.688 -187.840 257.663 1.00 74.89 ? 182 THR H CA 1 ATOM 7215 C C . THR C 3 182 ? -158.446 -186.988 257.706 1.00 74.48 ? 182 THR H C 1 ATOM 7216 O O . THR C 3 182 ? -157.717 -186.900 256.723 1.00 76.53 ? 182 THR H O 1 ATOM 7217 C CB . THR C 3 182 ? -159.328 -189.280 257.990 1.00 79.30 ? 182 THR H CB 1 ATOM 7218 O OG1 . THR C 3 182 ? -160.514 -190.091 257.934 1.00 85.51 ? 182 THR H OG1 1 ATOM 7219 C CG2 . THR C 3 182 ? -158.706 -189.348 259.383 1.00 72.51 ? 182 THR H CG2 1 ATOM 7220 N N . LEU C 3 183 ? -158.194 -186.364 258.844 1.00 75.34 ? 183 LEU H N 1 ATOM 7221 C CA . LEU C 3 183 ? -157.094 -185.423 258.945 1.00 75.48 ? 183 LEU H CA 1 ATOM 7222 C C . LEU C 3 183 ? -156.455 -185.563 260.326 1.00 78.97 ? 183 LEU H C 1 ATOM 7223 O O . LEU C 3 183 ? -157.066 -186.126 261.250 1.00 78.86 ? 183 LEU H O 1 ATOM 7224 C CB . LEU C 3 183 ? -157.606 -184.005 258.686 1.00 77.13 ? 183 LEU H CB 1 ATOM 7225 C CG . LEU C 3 183 ? -156.711 -182.778 258.810 1.00 76.57 ? 183 LEU H CG 1 ATOM 7226 C CD1 . LEU C 3 183 ? -157.174 -181.738 257.804 1.00 71.96 ? 183 LEU H CD1 1 ATOM 7227 C CD2 . LEU C 3 183 ? -156.772 -182.219 260.227 1.00 76.21 ? 183 LEU H CD2 1 ATOM 7228 N N . SER C 3 184 ? -155.216 -185.103 260.469 1.00 77.35 ? 184 SER H N 1 ATOM 7229 C CA . SER C 3 184 ? -154.551 -185.185 261.763 1.00 78.20 ? 184 SER H CA 1 ATOM 7230 C C . SER C 3 184 ? -153.496 -184.115 261.903 1.00 82.04 ? 184 SER H C 1 ATOM 7231 O O . SER C 3 184 ? -153.022 -183.561 260.905 1.00 82.61 ? 184 SER H O 1 ATOM 7232 C CB . SER C 3 184 ? -153.913 -186.557 261.969 1.00 78.54 ? 184 SER H CB 1 ATOM 7233 O OG . SER C 3 184 ? -152.783 -186.727 261.135 1.00 81.22 ? 184 SER H OG 1 ATOM 7234 N N . SER C 3 185 ? -153.128 -183.828 263.148 1.00 85.28 ? 185 SER H N 1 ATOM 7235 C CA . SER C 3 185 ? -152.084 -182.856 263.429 1.00 82.56 ? 185 SER H CA 1 ATOM 7236 C C . SER C 3 185 ? -151.220 -183.311 264.588 1.00 85.68 ? 185 SER H C 1 ATOM 7237 O O . SER C 3 185 ? -151.713 -183.883 265.558 1.00 89.48 ? 185 SER H O 1 ATOM 7238 C CB . SER C 3 185 ? -152.690 -181.496 263.742 1.00 82.33 ? 185 SER H CB 1 ATOM 7239 O OG . SER C 3 185 ? -151.691 -180.498 263.753 1.00 82.19 ? 185 SER H OG 1 ATOM 7240 N N . SER C 3 186 ? -149.923 -183.068 264.475 1.00 85.32 ? 186 SER H N 1 ATOM 7241 C CA . SER C 3 186 ? -149.010 -183.346 265.565 1.00 88.26 ? 186 SER H CA 1 ATOM 7242 C C . SER C 3 186 ? -148.307 -182.060 265.983 1.00 95.13 ? 186 SER H C 1 ATOM 7243 O O . SER C 3 186 ? -147.932 -181.232 265.147 1.00 95.48 ? 186 SER H O 1 ATOM 7244 C CB . SER C 3 186 ? -147.984 -184.403 265.167 1.00 90.17 ? 186 SER H CB 1 ATOM 7245 O OG . SER C 3 186 ? -146.926 -183.842 264.404 1.00 91.95 ? 186 SER H OG 1 ATOM 7246 N N . VAL C 3 187 ? -148.132 -181.897 267.286 1.00 101.23 ? 187 VAL H N 1 ATOM 7247 C CA . VAL C 3 187 ? -147.457 -180.730 267.829 1.00 101.02 ? 187 VAL H CA 1 ATOM 7248 C C . VAL C 3 187 ? -146.491 -181.190 268.901 1.00 99.44 ? 187 VAL H C 1 ATOM 7249 O O . VAL C 3 187 ? -146.810 -182.093 269.676 1.00 99.98 ? 187 VAL H O 1 ATOM 7250 C CB . VAL C 3 187 ? -148.454 -179.725 268.412 1.00 97.97 ? 187 VAL H CB 1 ATOM 7251 C CG1 . VAL C 3 187 ? -149.258 -180.368 269.532 1.00 93.27 ? 187 VAL H CG1 1 ATOM 7252 C CG2 . VAL C 3 187 ? -147.727 -178.487 268.893 1.00 95.81 ? 187 VAL H CG2 1 ATOM 7253 N N . THR C 3 188 ? -145.306 -180.591 268.939 1.00 102.49 ? 188 THR H N 1 ATOM 7254 C CA . THR C 3 188 ? -144.310 -180.998 269.929 1.00 109.51 ? 188 THR H CA 1 ATOM 7255 C C . THR C 3 188 ? -143.791 -179.814 270.745 1.00 106.80 ? 188 THR H C 1 ATOM 7256 O O . THR C 3 188 ? -143.368 -178.785 270.208 1.00 102.74 ? 188 THR H O 1 ATOM 7257 C CB . THR C 3 188 ? -143.122 -181.728 269.272 1.00 104.40 ? 188 THR H CB 1 ATOM 7258 O OG1 . THR C 3 188 ? -142.501 -180.858 268.320 1.00 109.81 ? 188 THR H OG1 1 ATOM 7259 C CG2 . THR C 3 188 ? -143.597 -182.994 268.565 1.00 100.47 ? 188 THR H CG2 1 ATOM 7260 N N . VAL C 3 189 ? -143.844 -179.979 272.058 1.00 110.08 ? 189 VAL H N 1 ATOM 7261 C CA . VAL C 3 189 ? -143.379 -178.961 272.976 1.00 117.54 ? 189 VAL H CA 1 ATOM 7262 C C . VAL C 3 189 ? -142.445 -179.626 273.988 1.00 120.91 ? 189 VAL H C 1 ATOM 7263 O O . VAL C 3 189 ? -142.492 -180.851 274.179 1.00 115.31 ? 189 VAL H O 1 ATOM 7264 C CB . VAL C 3 189 ? -144.556 -178.251 273.689 1.00 113.82 ? 189 VAL H CB 1 ATOM 7265 N N . THR C 3 190 ? -141.589 -178.820 274.615 1.00 123.12 ? 190 THR H N 1 ATOM 7266 C CA . THR C 3 190 ? -140.618 -179.313 275.587 1.00 120.08 ? 190 THR H CA 1 ATOM 7267 C C . THR C 3 190 ? -141.323 -180.004 276.749 1.00 118.30 ? 190 THR H C 1 ATOM 7268 O O . THR C 3 190 ? -142.422 -179.604 277.149 1.00 118.36 ? 190 THR H O 1 ATOM 7269 C CB . THR C 3 190 ? -139.745 -178.176 276.127 1.00 118.49 ? 190 THR H CB 1 ATOM 7270 O OG1 . THR C 3 190 ? -140.584 -177.198 276.756 1.00 120.69 ? 190 THR H OG1 1 ATOM 7271 C CG2 . THR C 3 190 ? -138.971 -177.521 274.995 1.00 112.92 ? 190 THR H CG2 1 ATOM 7272 N N . SER C 3 191 ? -140.680 -181.030 277.299 1.00 117.32 ? 191 SER H N 1 ATOM 7273 C CA . SER C 3 191 ? -141.307 -181.866 278.317 1.00 119.60 ? 191 SER H CA 1 ATOM 7274 C C . SER C 3 191 ? -141.718 -181.060 279.554 1.00 123.93 ? 191 SER H C 1 ATOM 7275 O O . SER C 3 191 ? -142.627 -181.460 280.287 1.00 118.77 ? 191 SER H O 1 ATOM 7276 C CB . SER C 3 191 ? -140.356 -182.995 278.726 1.00 121.17 ? 191 SER H CB 1 ATOM 7277 O OG . SER C 3 191 ? -141.024 -183.924 279.563 1.00 129.25 ? 191 SER H OG 1 ATOM 7278 N N . SER C 3 192 ? -141.050 -179.932 279.780 1.00 124.63 ? 192 SER H N 1 ATOM 7279 C CA . SER C 3 192 ? -141.467 -178.993 280.815 1.00 117.58 ? 192 SER H CA 1 ATOM 7280 C C . SER C 3 192 ? -142.861 -178.442 280.517 1.00 119.49 ? 192 SER H C 1 ATOM 7281 O O . SER C 3 192 ? -143.699 -178.315 281.417 1.00 117.67 ? 192 SER H O 1 ATOM 7282 C CB . SER C 3 192 ? -140.475 -177.826 280.920 1.00 117.28 ? 192 SER H CB 1 ATOM 7283 O OG . SER C 3 192 ? -139.146 -178.246 280.676 1.00 121.67 ? 192 SER H OG 1 ATOM 7284 N N . THR C 3 193 ? -143.115 -178.155 279.241 1.00 120.55 ? 193 THR H N 1 ATOM 7285 C CA . THR C 3 193 ? -144.333 -177.461 278.821 1.00 119.29 ? 193 THR H CA 1 ATOM 7286 C C . THR C 3 193 ? -145.619 -178.268 279.033 1.00 117.60 ? 193 THR H C 1 ATOM 7287 O O . THR C 3 193 ? -146.674 -177.700 279.330 1.00 116.95 ? 193 THR H O 1 ATOM 7288 C CB . THR C 3 193 ? -144.246 -177.057 277.327 1.00 117.01 ? 193 THR H CB 1 ATOM 7289 O OG1 . THR C 3 193 ? -143.054 -176.292 277.104 1.00 119.20 ? 193 THR H OG1 1 ATOM 7290 C CG2 . THR C 3 193 ? -145.461 -176.228 276.907 1.00 116.76 ? 193 THR H CG2 1 ATOM 7291 N N . TRP C 3 194 ? -145.530 -179.587 278.899 1.00 111.78 ? 194 TRP H N 1 ATOM 7292 C CA . TRP C 3 194 ? -146.714 -180.433 279.023 1.00 110.23 ? 194 TRP H CA 1 ATOM 7293 C C . TRP C 3 194 ? -146.400 -181.631 279.924 1.00 110.46 ? 194 TRP H C 1 ATOM 7294 O O . TRP C 3 194 ? -145.271 -182.128 279.923 1.00 116.16 ? 194 TRP H O 1 ATOM 7295 C CB . TRP C 3 194 ? -147.187 -180.891 277.623 1.00 113.88 ? 194 TRP H CB 1 ATOM 7296 C CG . TRP C 3 194 ? -148.493 -181.669 277.608 1.00 106.59 ? 194 TRP H CG 1 ATOM 7297 C CD1 . TRP C 3 194 ? -149.758 -181.158 277.491 1.00 99.86 ? 194 TRP H CD1 1 ATOM 7298 C CD2 . TRP C 3 194 ? -148.643 -183.091 277.720 1.00 99.82 ? 194 TRP H CD2 1 ATOM 7299 N NE1 . TRP C 3 194 ? -150.675 -182.174 277.537 1.00 95.14 ? 194 TRP H NE1 1 ATOM 7300 C CE2 . TRP C 3 194 ? -150.019 -183.370 277.679 1.00 97.62 ? 194 TRP H CE2 1 ATOM 7301 C CE3 . TRP C 3 194 ? -147.742 -184.154 277.857 1.00 101.60 ? 194 TRP H CE3 1 ATOM 7302 C CZ2 . TRP C 3 194 ? -150.522 -184.673 277.765 1.00 105.02 ? 194 TRP H CZ2 1 ATOM 7303 C CZ3 . TRP C 3 194 ? -148.238 -185.444 277.942 1.00 100.54 ? 194 TRP H CZ3 1 ATOM 7304 C CH2 . TRP C 3 194 ? -149.616 -185.694 277.895 1.00 103.44 ? 194 TRP H CH2 1 ATOM 7305 N N . PRO C 3 195 ? -147.397 -182.112 280.688 1.00 103.11 ? 195 PRO H N 1 ATOM 7306 C CA . PRO C 3 195 ? -148.759 -181.573 280.821 1.00 103.15 ? 195 PRO H CA 1 ATOM 7307 C C . PRO C 3 195 ? -148.890 -180.414 281.809 1.00 111.68 ? 195 PRO H C 1 ATOM 7308 O O . PRO C 3 195 ? -149.982 -180.188 282.334 1.00 114.43 ? 195 PRO H O 1 ATOM 7309 C CB . PRO C 3 195 ? -149.558 -182.778 281.318 1.00 102.19 ? 195 PRO H CB 1 ATOM 7310 C CG . PRO C 3 195 ? -148.570 -183.595 282.060 1.00 104.36 ? 195 PRO H CG 1 ATOM 7311 C CD . PRO C 3 195 ? -147.256 -183.423 281.350 1.00 99.76 ? 195 PRO H CD 1 ATOM 7312 N N . SER C 3 196 ? -147.796 -179.697 282.053 1.00 116.41 ? 196 SER H N 1 ATOM 7313 C CA . SER C 3 196 ? -147.777 -178.601 283.017 1.00 110.43 ? 196 SER H CA 1 ATOM 7314 C C . SER C 3 196 ? -148.693 -177.461 282.581 1.00 116.13 ? 196 SER H C 1 ATOM 7315 O O . SER C 3 196 ? -149.254 -176.746 283.412 1.00 117.01 ? 196 SER H O 1 ATOM 7316 C CB . SER C 3 196 ? -146.348 -178.090 283.191 1.00 112.56 ? 196 SER H CB 1 ATOM 7317 O OG . SER C 3 196 ? -145.415 -179.145 283.008 1.00 113.30 ? 196 SER H OG 1 ATOM 7318 N N . GLN C 3 197 ? -148.841 -177.307 281.268 1.00 121.21 ? 197 GLN H N 1 ATOM 7319 C CA . GLN C 3 197 ? -149.728 -176.297 280.693 1.00 122.90 ? 197 GLN H CA 1 ATOM 7320 C C . GLN C 3 197 ? -150.695 -176.940 279.697 1.00 120.00 ? 197 GLN H C 1 ATOM 7321 O O . GLN C 3 197 ? -150.319 -177.859 278.966 1.00 113.98 ? 197 GLN H O 1 ATOM 7322 C CB . GLN C 3 197 ? -148.920 -175.197 280.008 1.00 116.26 ? 197 GLN H CB 1 ATOM 7323 C CG . GLN C 3 197 ? -148.024 -174.425 280.947 1.00 119.71 ? 197 GLN H CG 1 ATOM 7324 C CD . GLN C 3 197 ? -147.078 -173.498 280.208 1.00 126.60 ? 197 GLN H CD 1 ATOM 7325 O OE1 . GLN C 3 197 ? -146.591 -173.824 279.123 1.00 125.82 ? 197 GLN H OE1 1 ATOM 7326 N NE2 . GLN C 3 197 ? -146.818 -172.329 280.789 1.00 126.10 ? 197 GLN H NE2 1 ATOM 7327 N N . SER C 3 198 ? -151.936 -176.453 279.677 1.00 123.28 ? 198 SER H N 1 ATOM 7328 C CA . SER C 3 198 ? -152.983 -177.048 278.853 1.00 118.49 ? 198 SER H CA 1 ATOM 7329 C C . SER C 3 198 ? -152.641 -176.939 277.366 1.00 116.34 ? 198 SER H C 1 ATOM 7330 O O . SER C 3 198 ? -152.178 -175.896 276.886 1.00 111.28 ? 198 SER H O 1 ATOM 7331 C CB . SER C 3 198 ? -154.340 -176.390 279.143 1.00 101.57 ? 198 SER H CB 1 ATOM 7332 N N . ILE C 3 199 ? -152.865 -178.034 276.648 1.00 112.63 ? 199 ILE H N 1 ATOM 7333 C CA . ILE C 3 199 ? -152.693 -178.055 275.202 1.00 108.65 ? 199 ILE H CA 1 ATOM 7334 C C . ILE C 3 199 ? -154.000 -178.487 274.569 1.00 104.94 ? 199 ILE H C 1 ATOM 7335 O O . ILE C 3 199 ? -154.407 -179.645 274.682 1.00 105.89 ? 199 ILE H O 1 ATOM 7336 C CB . ILE C 3 199 ? -151.564 -179.005 274.762 1.00 107.87 ? 199 ILE H CB 1 ATOM 7337 C CG1 . ILE C 3 199 ? -150.244 -178.625 275.437 1.00 108.15 ? 199 ILE H CG1 1 ATOM 7338 C CG2 . ILE C 3 199 ? -151.402 -178.964 273.262 1.00 102.95 ? 199 ILE H CG2 1 ATOM 7339 C CD1 . ILE C 3 199 ? -149.783 -177.222 275.098 1.00 110.40 ? 199 ILE H CD1 1 ATOM 7340 N N . THR C 3 200 ? -154.677 -177.545 273.927 1.00 102.06 ? 200 THR H N 1 ATOM 7341 C CA . THR C 3 200 ? -155.944 -177.860 273.289 1.00 104.27 ? 200 THR H CA 1 ATOM 7342 C C . THR C 3 200 ? -155.861 -177.825 271.757 1.00 102.18 ? 200 THR H C 1 ATOM 7343 O O . THR C 3 200 ? -155.345 -176.881 271.145 1.00 101.82 ? 200 THR H O 1 ATOM 7344 C CB . THR C 3 200 ? -157.056 -176.902 273.751 1.00 105.50 ? 200 THR H CB 1 ATOM 7345 O OG1 . THR C 3 200 ? -158.302 -177.281 273.149 1.00 110.41 ? 200 THR H OG1 1 ATOM 7346 C CG2 . THR C 3 200 ? -156.725 -175.465 273.358 1.00 111.08 ? 200 THR H CG2 1 ATOM 7347 N N . CYS C 3 201 ? -156.394 -178.872 271.150 1.00 101.98 ? 201 CYS H N 1 ATOM 7348 C CA . CYS C 3 201 ? -156.559 -178.942 269.709 1.00 102.04 ? 201 CYS H CA 1 ATOM 7349 C C . CYS C 3 201 ? -157.938 -178.393 269.346 1.00 101.86 ? 201 CYS H C 1 ATOM 7350 O O . CYS C 3 201 ? -158.959 -178.989 269.702 1.00 100.54 ? 201 CYS H O 1 ATOM 7351 C CB . CYS C 3 201 ? -156.391 -180.389 269.245 1.00 100.51 ? 201 CYS H CB 1 ATOM 7352 S SG . CYS C 3 201 ? -156.893 -180.717 267.573 1.00 108.33 ? 201 CYS H SG 1 ATOM 7353 N N . ASN C 3 202 ? -157.988 -177.250 268.669 1.00 98.27 ? 202 ASN H N 1 ATOM 7354 C CA . ASN C 3 202 ? -159.288 -176.663 268.350 1.00 99.56 ? 202 ASN H CA 1 ATOM 7355 C C . ASN C 3 202 ? -159.585 -176.685 266.850 1.00 96.54 ? 202 ASN H C 1 ATOM 7356 O O . ASN C 3 202 ? -158.801 -176.207 266.029 1.00 93.25 ? 202 ASN H O 1 ATOM 7357 C CB . ASN C 3 202 ? -159.401 -175.238 268.915 1.00 101.52 ? 202 ASN H CB 1 ATOM 7358 C CG . ASN C 3 202 ? -158.207 -174.378 268.592 1.00 102.38 ? 202 ASN H CG 1 ATOM 7359 O OD1 . ASN C 3 202 ? -157.202 -174.858 268.082 1.00 108.00 ? 202 ASN H OD1 1 ATOM 7360 N ND2 . ASN C 3 202 ? -158.309 -173.094 268.896 1.00 104.59 ? 202 ASN H ND2 1 ATOM 7361 N N . VAL C 3 203 ? -160.740 -177.263 266.522 1.00 94.89 ? 203 VAL H N 1 ATOM 7362 C CA . VAL C 3 203 ? -161.095 -177.621 265.156 1.00 83.38 ? 203 VAL H CA 1 ATOM 7363 C C . VAL C 3 203 ? -162.352 -176.920 264.676 1.00 87.97 ? 203 VAL H C 1 ATOM 7364 O O . VAL C 3 203 ? -163.325 -176.787 265.422 1.00 94.14 ? 203 VAL H O 1 ATOM 7365 C CB . VAL C 3 203 ? -161.314 -179.134 265.042 1.00 82.17 ? 203 VAL H CB 1 ATOM 7366 C CG1 . VAL C 3 203 ? -161.682 -179.506 263.623 1.00 83.68 ? 203 VAL H CG1 1 ATOM 7367 C CG2 . VAL C 3 203 ? -160.074 -179.878 265.497 1.00 88.95 ? 203 VAL H CG2 1 ATOM 7368 N N . ALA C 3 204 ? -162.349 -176.493 263.422 1.00 83.79 ? 204 ALA H N 1 ATOM 7369 C CA . ALA C 3 204 ? -163.508 -175.811 262.871 1.00 83.93 ? 204 ALA H CA 1 ATOM 7370 C C . ALA C 3 204 ? -163.910 -176.422 261.524 1.00 88.39 ? 204 ALA H C 1 ATOM 7371 O O . ALA C 3 204 ? -163.077 -176.612 260.633 1.00 85.82 ? 204 ALA H O 1 ATOM 7372 C CB . ALA C 3 204 ? -163.224 -174.330 262.717 1.00 84.11 ? 204 ALA H CB 1 ATOM 7373 N N . HIS C 3 205 ? -165.184 -176.765 261.396 1.00 87.50 ? 205 HIS H N 1 ATOM 7374 C CA . HIS C 3 205 ? -165.715 -177.280 260.150 1.00 81.28 ? 205 HIS H CA 1 ATOM 7375 C C . HIS C 3 205 ? -167.039 -176.574 259.827 1.00 81.77 ? 205 HIS H C 1 ATOM 7376 O O . HIS C 3 205 ? -168.111 -177.130 260.092 1.00 84.80 ? 205 HIS H O 1 ATOM 7377 C CB . HIS C 3 205 ? -165.885 -178.802 260.223 1.00 80.47 ? 205 HIS H CB 1 ATOM 7378 C CG . HIS C 3 205 ? -166.331 -179.420 258.934 1.00 80.60 ? 205 HIS H CG 1 ATOM 7379 N ND1 . HIS C 3 205 ? -167.492 -180.156 258.827 1.00 80.77 ? 205 HIS H ND1 1 ATOM 7380 C CD2 . HIS C 3 205 ? -165.779 -179.407 257.696 1.00 78.05 ? 205 HIS H CD2 1 ATOM 7381 C CE1 . HIS C 3 205 ? -167.633 -180.574 257.581 1.00 77.62 ? 205 HIS H CE1 1 ATOM 7382 N NE2 . HIS C 3 205 ? -166.606 -180.134 256.875 1.00 77.43 ? 205 HIS H NE2 1 ATOM 7383 N N . PRO C 3 206 ? -166.974 -175.364 259.258 1.00 76.41 ? 206 PRO H N 1 ATOM 7384 C CA . PRO C 3 206 ? -168.133 -174.492 259.063 1.00 76.07 ? 206 PRO H CA 1 ATOM 7385 C C . PRO C 3 206 ? -169.237 -175.142 258.242 1.00 79.31 ? 206 PRO H C 1 ATOM 7386 O O . PRO C 3 206 ? -170.423 -174.870 258.476 1.00 81.64 ? 206 PRO H O 1 ATOM 7387 C CB . PRO C 3 206 ? -167.560 -173.294 258.302 1.00 70.69 ? 206 PRO H CB 1 ATOM 7388 C CG . PRO C 3 206 ? -166.120 -173.299 258.603 1.00 77.30 ? 206 PRO H CG 1 ATOM 7389 C CD . PRO C 3 206 ? -165.732 -174.740 258.767 1.00 80.34 ? 206 PRO H CD 1 ATOM 7390 N N . ALA C 3 207 ? -168.861 -175.978 257.280 1.00 81.84 ? 207 ALA H N 1 ATOM 7391 C CA . ALA C 3 207 ? -169.842 -176.579 256.391 1.00 75.80 ? 207 ALA H CA 1 ATOM 7392 C C . ALA C 3 207 ? -170.869 -177.378 257.199 1.00 78.95 ? 207 ALA H C 1 ATOM 7393 O O . ALA C 3 207 ? -172.028 -177.473 256.801 1.00 79.38 ? 207 ALA H O 1 ATOM 7394 C CB . ALA C 3 207 ? -169.141 -177.468 255.372 1.00 68.43 ? 207 ALA H CB 1 ATOM 7395 N N . SER C 3 208 ? -170.435 -177.924 258.339 1.00 81.13 ? 208 SER H N 1 ATOM 7396 C CA . SER C 3 208 ? -171.314 -178.670 259.243 1.00 79.36 ? 208 SER H CA 1 ATOM 7397 C C . SER C 3 208 ? -171.549 -177.960 260.569 1.00 81.63 ? 208 SER H C 1 ATOM 7398 O O . SER C 3 208 ? -172.072 -178.561 261.507 1.00 84.71 ? 208 SER H O 1 ATOM 7399 C CB . SER C 3 208 ? -170.760 -180.068 259.530 1.00 77.84 ? 208 SER H CB 1 ATOM 7400 O OG . SER C 3 208 ? -169.670 -180.036 260.431 1.00 78.24 ? 208 SER H OG 1 ATOM 7401 N N . SER C 3 209 ? -171.142 -176.696 260.646 1.00 80.47 ? 209 SER H N 1 ATOM 7402 C CA . SER C 3 209 ? -171.357 -175.861 261.830 1.00 80.94 ? 209 SER H CA 1 ATOM 7403 C C . SER C 3 209 ? -170.654 -176.350 263.083 1.00 77.97 ? 209 SER H C 1 ATOM 7404 O O . SER C 3 209 ? -171.046 -175.975 264.182 1.00 86.04 ? 209 SER H O 1 ATOM 7405 C CB . SER C 3 209 ? -172.852 -175.750 262.138 1.00 76.86 ? 209 SER H CB 1 ATOM 7406 O OG . SER C 3 209 ? -173.584 -175.382 260.989 1.00 82.01 ? 209 SER H OG 1 ATOM 7407 N N . THR C 3 210 ? -169.635 -177.187 262.924 1.00 78.39 ? 210 THR H N 1 ATOM 7408 C CA . THR C 3 210 ? -168.858 -177.671 264.063 1.00 81.78 ? 210 THR H CA 1 ATOM 7409 C C . THR C 3 210 ? -167.836 -176.644 264.561 1.00 88.25 ? 210 THR H C 1 ATOM 7410 O O . THR C 3 210 ? -167.328 -175.817 263.793 1.00 88.89 ? 210 THR H O 1 ATOM 7411 C CB . THR C 3 210 ? -168.136 -178.991 263.721 1.00 81.86 ? 210 THR H CB 1 ATOM 7412 O OG1 . THR C 3 210 ? -169.090 -179.935 263.223 1.00 77.55 ? 210 THR H OG1 1 ATOM 7413 C CG2 . THR C 3 210 ? -167.460 -179.578 264.954 1.00 82.49 ? 210 THR H CG2 1 ATOM 7414 N N . LYS C 3 211 ? -167.549 -176.707 265.859 1.00 89.84 ? 211 LYS H N 1 ATOM 7415 C CA . LYS C 3 211 ? -166.518 -175.879 266.478 1.00 87.61 ? 211 LYS H CA 1 ATOM 7416 C C . LYS C 3 211 ? -166.079 -176.517 267.783 1.00 87.81 ? 211 LYS H C 1 ATOM 7417 O O . LYS C 3 211 ? -166.425 -176.042 268.856 1.00 97.42 ? 211 LYS H O 1 ATOM 7418 C CB . LYS C 3 211 ? -167.024 -174.454 266.727 1.00 97.00 ? 211 LYS H CB 1 ATOM 7419 C CG . LYS C 3 211 ? -166.512 -173.398 265.739 1.00 94.26 ? 211 LYS H CG 1 ATOM 7420 C CD . LYS C 3 211 ? -167.020 -171.995 266.098 1.00 100.75 ? 211 LYS H CD 1 ATOM 7421 C CE . LYS C 3 211 ? -168.560 -171.953 266.161 1.00 118.35 ? 211 LYS H CE 1 ATOM 7422 N NZ . LYS C 3 211 ? -169.107 -170.582 266.419 1.00 117.89 ? 211 LYS H NZ 1 ATOM 7423 N N . VAL C 3 212 ? -165.347 -177.617 267.676 1.00 94.00 ? 212 VAL H N 1 ATOM 7424 C CA . VAL C 3 212 ? -164.833 -178.344 268.832 1.00 97.17 ? 212 VAL H CA 1 ATOM 7425 C C . VAL C 3 212 ? -163.472 -177.840 269.332 1.00 99.87 ? 212 VAL H C 1 ATOM 7426 O O . VAL C 3 212 ? -162.649 -177.363 268.542 1.00 96.17 ? 212 VAL H O 1 ATOM 7427 C CB . VAL C 3 212 ? -164.690 -179.846 268.507 1.00 90.54 ? 212 VAL H CB 1 ATOM 7428 C CG1 . VAL C 3 212 ? -164.343 -180.630 269.754 1.00 97.04 ? 212 VAL H CG1 1 ATOM 7429 C CG2 . VAL C 3 212 ? -165.961 -180.373 267.880 1.00 90.89 ? 212 VAL H CG2 1 ATOM 7430 N N . ASP C 3 213 ? -163.245 -177.968 270.643 1.00 102.85 ? 213 ASP H N 1 ATOM 7431 C CA . ASP C 3 213 ? -161.915 -177.831 271.243 1.00 100.54 ? 213 ASP H CA 1 ATOM 7432 C C . ASP C 3 213 ? -161.637 -179.101 272.024 1.00 104.78 ? 213 ASP H C 1 ATOM 7433 O O . ASP C 3 213 ? -162.569 -179.708 272.548 1.00 105.48 ? 213 ASP H O 1 ATOM 7434 C CB . ASP C 3 213 ? -161.821 -176.627 272.174 1.00 96.80 ? 213 ASP H CB 1 ATOM 7435 C CG . ASP C 3 213 ? -162.343 -175.347 271.544 1.00 108.90 ? 213 ASP H CG 1 ATOM 7436 O OD1 . ASP C 3 213 ? -162.361 -175.230 270.296 1.00 105.86 ? 213 ASP H OD1 1 ATOM 7437 O OD2 . ASP C 3 213 ? -162.729 -174.437 272.311 1.00 120.29 ? 213 ASP H OD2 1 ATOM 7438 N N . LYS C 3 214 ? -160.374 -179.514 272.108 1.00 107.29 ? 214 LYS H N 1 ATOM 7439 C CA . LYS C 3 214 ? -160.037 -180.752 272.820 1.00 104.63 ? 214 LYS H CA 1 ATOM 7440 C C . LYS C 3 214 ? -158.744 -180.658 273.613 1.00 106.38 ? 214 LYS H C 1 ATOM 7441 O O . LYS C 3 214 ? -157.656 -180.819 273.066 1.00 107.72 ? 214 LYS H O 1 ATOM 7442 C CB . LYS C 3 214 ? -159.941 -181.925 271.844 1.00 95.43 ? 214 LYS H CB 1 ATOM 7443 C CG . LYS C 3 214 ? -161.211 -182.156 271.051 1.00 103.42 ? 214 LYS H CG 1 ATOM 7444 C CD . LYS C 3 214 ? -162.394 -182.564 271.941 1.00 103.28 ? 214 LYS H CD 1 ATOM 7445 C CE . LYS C 3 214 ? -162.214 -183.972 272.502 1.00 108.77 ? 214 LYS H CE 1 ATOM 7446 N NZ . LYS C 3 214 ? -163.512 -184.665 272.762 1.00 108.89 ? 214 LYS H NZ 1 ATOM 7447 N N . LYS C 3 215 ? -158.869 -180.406 274.909 1.00 108.95 ? 215 LYS H N 1 ATOM 7448 C CA . LYS C 3 215 ? -157.718 -180.439 275.791 1.00 110.26 ? 215 LYS H CA 1 ATOM 7449 C C . LYS C 3 215 ? -157.185 -181.873 275.842 1.00 110.29 ? 215 LYS H C 1 ATOM 7450 O O . LYS C 3 215 ? -157.954 -182.835 275.793 1.00 102.27 ? 215 LYS H O 1 ATOM 7451 C CB . LYS C 3 215 ? -158.086 -179.925 277.189 1.00 116.74 ? 215 LYS H CB 1 ATOM 7452 C CG . LYS C 3 215 ? -156.887 -179.682 278.107 1.00 119.48 ? 215 LYS H CG 1 ATOM 7453 C CD . LYS C 3 215 ? -157.314 -179.278 279.511 1.00 119.96 ? 215 LYS H CD 1 ATOM 7454 C CE . LYS C 3 215 ? -158.202 -180.346 280.154 1.00 128.18 ? 215 LYS H CE 1 ATOM 7455 N NZ . LYS C 3 215 ? -158.518 -180.058 281.593 1.00 127.03 ? 215 LYS H NZ 1 ATOM 7456 N N . ILE C 3 216 ? -155.866 -182.003 275.928 1.00 113.28 ? 216 ILE H N 1 ATOM 7457 C CA . ILE C 3 216 ? -155.208 -183.305 275.880 1.00 113.98 ? 216 ILE H CA 1 ATOM 7458 C C . ILE C 3 216 ? -154.630 -183.743 277.228 1.00 115.02 ? 216 ILE H C 1 ATOM 7459 O O . ILE C 3 216 ? -153.658 -183.156 277.708 1.00 114.16 ? 216 ILE H O 1 ATOM 7460 C CB . ILE C 3 216 ? -154.070 -183.291 274.839 1.00 110.66 ? 216 ILE H CB 1 ATOM 7461 C CG1 . ILE C 3 216 ? -154.615 -182.921 273.461 1.00 104.01 ? 216 ILE H CG1 1 ATOM 7462 C CG2 . ILE C 3 216 ? -153.356 -184.632 274.797 1.00 110.74 ? 216 ILE H CG2 1 ATOM 7463 C CD1 . ILE C 3 216 ? -153.585 -182.988 272.375 1.00 103.63 ? 216 ILE H CD1 1 ATOM 7464 N N . GLU C 3 217 ? -155.194 -184.794 277.818 1.00 117.90 ? 217 GLU H N 1 ATOM 7465 C CA . GLU C 3 217 ? -154.720 -185.263 279.121 1.00 118.07 ? 217 GLU H CA 1 ATOM 7466 C C . GLU C 3 217 ? -154.216 -186.692 279.020 1.00 118.18 ? 217 GLU H C 1 ATOM 7467 O O . GLU C 3 217 ? -154.752 -187.487 278.249 1.00 123.84 ? 217 GLU H O 1 ATOM 7468 C CB . GLU C 3 217 ? -155.834 -185.174 280.161 1.00 118.72 ? 217 GLU H CB 1 ATOM 7469 C CG . GLU C 3 217 ? -156.596 -183.853 280.134 1.00 124.14 ? 217 GLU H CG 1 ATOM 7470 C CD . GLU C 3 217 ? -157.668 -183.770 281.208 1.00 138.95 ? 217 GLU H CD 1 ATOM 7471 O OE1 . GLU C 3 217 ? -158.375 -184.783 281.430 1.00 141.58 ? 217 GLU H OE1 1 ATOM 7472 O OE2 . GLU C 3 217 ? -157.797 -182.693 281.836 1.00 139.20 ? 217 GLU H OE2 1 ATOM 7473 N N . PRO C 3 218 ? -153.185 -187.029 279.807 1.00 117.26 ? 218 PRO H N 1 ATOM 7474 C CA . PRO C 3 218 ? -152.493 -188.320 279.661 1.00 119.32 ? 218 PRO H CA 1 ATOM 7475 C C . PRO C 3 218 ? -153.147 -189.506 280.390 1.00 120.79 ? 218 PRO H C 1 ATOM 7476 O O . PRO C 3 218 ? -152.435 -190.262 281.061 1.00 122.02 ? 218 PRO H O 1 ATOM 7477 C CB . PRO C 3 218 ? -151.104 -188.031 280.245 1.00 117.06 ? 218 PRO H CB 1 ATOM 7478 C CG . PRO C 3 218 ? -151.336 -186.931 281.240 1.00 113.54 ? 218 PRO H CG 1 ATOM 7479 C CD . PRO C 3 218 ? -152.471 -186.100 280.702 1.00 113.66 ? 218 PRO H CD 1 ATOM 7480 N N . ARG C 3 219 ? -154.461 -189.679 280.231 1.00 122.46 ? 219 ARG H N 1 ATOM 7481 C CA . ARG C 3 219 ? -155.204 -190.771 280.880 1.00 125.93 ? 219 ARG H CA 1 ATOM 7482 C C . ARG C 3 219 ? -154.498 -192.126 280.783 1.00 123.29 ? 219 ARG H C 1 ATOM 7483 O O . ARG C 3 219 ? -153.920 -192.607 281.763 1.00 121.05 ? 219 ARG H O 1 ATOM 7484 C CB . ARG C 3 219 ? -156.613 -190.892 280.283 1.00 114.64 ? 219 ARG H CB 1 HETATM 7485 C CAA . Y01 D 4 . ? -137.970 -139.226 206.717 1.00 84.96 ? 701 Y01 C CAA 1 HETATM 7486 C CBA . Y01 D 4 . ? -138.354 -140.693 206.474 1.00 83.49 ? 701 Y01 C CBA 1 HETATM 7487 C CAB . Y01 D 4 . ? -137.224 -141.460 205.737 1.00 75.90 ? 701 Y01 C CAB 1 HETATM 7488 C CAN . Y01 D 4 . ? -138.672 -141.380 207.810 1.00 89.73 ? 701 Y01 C CAN 1 HETATM 7489 C CAJ . Y01 D 4 . ? -140.053 -140.938 208.381 1.00 82.22 ? 701 Y01 C CAJ 1 HETATM 7490 C CAO . Y01 D 4 . ? -140.049 -140.979 209.940 1.00 87.51 ? 701 Y01 C CAO 1 HETATM 7491 C CBB . Y01 D 4 . ? -141.234 -141.884 210.552 1.00 91.29 ? 701 Y01 C CBB 1 HETATM 7492 C CAC . Y01 D 4 . ? -141.151 -143.301 209.933 1.00 86.82 ? 701 Y01 C CAC 1 HETATM 7493 C CBE . Y01 D 4 . ? -141.063 -141.924 211.905 1.00 89.59 ? 701 Y01 C CBE 1 HETATM 7494 C CAP . Y01 D 4 . ? -140.802 -140.386 212.483 1.00 86.49 ? 701 Y01 C CAP 1 HETATM 7495 C CAQ . Y01 D 4 . ? -141.836 -140.217 213.642 1.00 91.63 ? 701 Y01 C CAQ 1 HETATM 7496 C CBG . Y01 D 4 . ? -142.159 -141.727 214.061 1.00 95.45 ? 701 Y01 C CBG 1 HETATM 7497 C CBI . Y01 D 4 . ? -142.405 -142.393 212.707 1.00 89.20 ? 701 Y01 C CBI 1 HETATM 7498 C CAE . Y01 D 4 . ? -143.516 -141.605 212.073 1.00 90.93 ? 701 Y01 C CAE 1 HETATM 7499 C CAU . Y01 D 4 . ? -142.846 -143.731 212.753 1.00 87.78 ? 701 Y01 C CAU 1 HETATM 7500 C CAS . Y01 D 4 . ? -144.022 -143.967 213.882 1.00 91.66 ? 701 Y01 C CAS 1 HETATM 7501 C CBF . Y01 D 4 . ? -143.507 -143.522 215.236 1.00 98.63 ? 701 Y01 C CBF 1 HETATM 7502 C CBD . Y01 D 4 . ? -143.146 -142.073 215.208 1.00 95.09 ? 701 Y01 C CBD 1 HETATM 7503 C CAK . Y01 D 4 . ? -142.480 -141.578 216.597 1.00 97.01 ? 701 Y01 C CAK 1 HETATM 7504 C CAI . Y01 D 4 . ? -143.329 -141.913 217.770 1.00 104.45 ? 701 Y01 C CAI 1 HETATM 7505 C CAZ . Y01 D 4 . ? -144.149 -143.403 217.755 1.00 105.88 ? 701 Y01 C CAZ 1 HETATM 7506 C CAV . Y01 D 4 . ? -144.852 -143.819 219.015 1.00 107.52 ? 701 Y01 C CAV 1 HETATM 7507 C CBH . Y01 D 4 . ? -144.586 -143.907 216.481 1.00 103.41 ? 701 Y01 C CBH 1 HETATM 7508 C CAD . Y01 D 4 . ? -145.951 -143.255 216.134 1.00 100.30 ? 701 Y01 C CAD 1 HETATM 7509 C CAT . Y01 D 4 . ? -144.769 -145.415 216.531 1.00 95.18 ? 701 Y01 C CAT 1 HETATM 7510 C CAR . Y01 D 4 . ? -145.639 -145.844 217.753 1.00 98.92 ? 701 Y01 C CAR 1 HETATM 7511 C CBC . Y01 D 4 . ? -145.064 -145.317 219.093 1.00 107.76 ? 701 Y01 C CBC 1 HETATM 7512 O OAW . Y01 D 4 . ? -145.948 -145.542 220.198 1.00 113.27 ? 701 Y01 C OAW 1 HETATM 7513 C CAY . Y01 D 4 . ? -146.298 -146.886 220.582 1.00 110.82 ? 701 Y01 C CAY 1 HETATM 7514 O OAG . Y01 D 4 . ? -145.441 -147.713 220.846 1.00 109.17 ? 701 Y01 C OAG 1 HETATM 7515 C CAM . Y01 D 4 . ? -147.789 -147.258 220.676 1.00 102.74 ? 701 Y01 C CAM 1 HETATM 7516 C CAL . Y01 D 4 . ? -148.091 -148.349 221.689 1.00 107.56 ? 701 Y01 C CAL 1 HETATM 7517 C CAX . Y01 D 4 . ? -148.410 -149.673 221.023 1.00 111.92 ? 701 Y01 C CAX 1 HETATM 7518 O OAH . Y01 D 4 . ? -147.457 -150.399 220.614 1.00 117.22 ? 701 Y01 C OAH 1 HETATM 7519 O OAF . Y01 D 4 . ? -149.619 -150.050 220.872 1.00 96.12 -1 701 Y01 C OAF 1 HETATM 7520 C C1 . NAG E 5 . ? -132.711 -144.476 165.758 1.00 120.11 ? 702 NAG C C1 1 HETATM 7521 C C2 . NAG E 5 . ? -133.543 -144.284 164.480 1.00 114.63 ? 702 NAG C C2 1 HETATM 7522 C C3 . NAG E 5 . ? -134.885 -145.009 164.587 1.00 114.64 ? 702 NAG C C3 1 HETATM 7523 C C4 . NAG E 5 . ? -134.688 -146.473 164.983 1.00 118.09 ? 702 NAG C C4 1 HETATM 7524 C C5 . NAG E 5 . ? -133.766 -146.588 166.201 1.00 118.52 ? 702 NAG C C5 1 HETATM 7525 C C6 . NAG E 5 . ? -133.442 -148.009 166.592 1.00 119.33 ? 702 NAG C C6 1 HETATM 7526 C C7 . NAG E 5 . ? -133.484 -142.336 163.002 1.00 122.86 ? 702 NAG C C7 1 HETATM 7527 C C8 . NAG E 5 . ? -133.719 -140.863 162.862 1.00 120.61 ? 702 NAG C C8 1 HETATM 7528 N N2 . NAG E 5 . ? -133.747 -142.858 164.199 1.00 118.59 ? 702 NAG C N2 1 HETATM 7529 O O3 . NAG E 5 . ? -135.602 -144.956 163.360 1.00 115.50 ? 702 NAG C O3 1 HETATM 7530 O O4 . NAG E 5 . ? -135.923 -147.102 165.327 1.00 116.45 ? 702 NAG C O4 1 HETATM 7531 O O5 . NAG E 5 . ? -132.512 -145.928 165.973 1.00 121.32 ? 702 NAG C O5 1 HETATM 7532 O O6 . NAG E 5 . ? -133.323 -148.146 168.003 1.00 115.97 ? 702 NAG C O6 1 HETATM 7533 O O7 . NAG E 5 . ? -133.092 -143.020 162.059 1.00 122.68 ? 702 NAG C O7 1 HETATM 7534 C C1 . MAL F 6 . ? -142.225 -140.933 165.648 1.00 98.50 ? 703 MAL C C1 1 HETATM 7535 C C2 . MAL F 6 . ? -141.623 -140.343 164.386 1.00 103.57 ? 703 MAL C C2 1 HETATM 7536 C C3 . MAL F 6 . ? -140.323 -141.084 164.063 1.00 101.00 ? 703 MAL C C3 1 HETATM 7537 C C4 . MAL F 6 . ? -139.330 -140.858 165.206 1.00 100.28 ? 703 MAL C C4 1 HETATM 7538 C C5 . MAL F 6 . ? -139.994 -141.181 166.542 1.00 101.45 ? 703 MAL C C5 1 HETATM 7539 C C6 . MAL F 6 . ? -140.063 -139.978 167.487 1.00 101.85 ? 703 MAL C C6 1 HETATM 7540 O O1 . MAL F 6 . ? -143.260 -141.782 165.225 1.00 97.49 ? 703 MAL C O1 1 HETATM 7541 O O2 . MAL F 6 . ? -142.596 -140.446 163.356 1.00 104.26 ? 703 MAL C O2 1 HETATM 7542 O O3 . MAL F 6 . ? -139.777 -140.637 162.839 1.00 97.56 ? 703 MAL C O3 1 HETATM 7543 O O4 . MAL F 6 . ? -138.170 -141.658 165.061 1.00 99.41 ? 703 MAL C O4 1 HETATM 7544 O O5 . MAL F 6 . ? -141.286 -141.736 166.329 1.00 99.39 ? 703 MAL C O5 1 HETATM 7545 O O6 . MAL F 6 . ? -139.915 -140.406 168.837 1.00 91.87 ? 703 MAL C O6 1 HETATM 7546 C "C1'" . MAL F 6 . ? -146.436 -143.158 167.459 1.00 93.95 ? 703 MAL C "C1'" 1 HETATM 7547 C "C2'" . MAL F 6 . ? -146.803 -142.475 166.127 1.00 95.70 ? 703 MAL C "C2'" 1 HETATM 7548 C "C3'" . MAL F 6 . ? -145.573 -142.391 165.215 1.00 96.01 ? 703 MAL C "C3'" 1 HETATM 7549 C "C4'" . MAL F 6 . ? -144.397 -141.880 166.043 1.00 101.90 ? 703 MAL C "C4'" 1 HETATM 7550 C "C5'" . MAL F 6 . ? -144.124 -142.800 167.235 1.00 98.47 ? 703 MAL C "C5'" 1 HETATM 7551 C "C6'" . MAL F 6 . ? -144.064 -142.032 168.560 1.00 93.69 ? 703 MAL C "C6'" 1 HETATM 7552 O "O1'" . MAL F 6 . ? -147.376 -144.126 167.910 1.00 89.32 ? 703 MAL C "O1'" 1 HETATM 7553 O "O2'" . MAL F 6 . ? -147.863 -143.138 165.474 1.00 104.40 ? 703 MAL C "O2'" 1 HETATM 7554 O "O3'" . MAL F 6 . ? -145.750 -141.542 164.096 1.00 95.63 ? 703 MAL C "O3'" 1 HETATM 7555 O "O5'" . MAL F 6 . ? -145.165 -143.762 167.313 1.00 102.06 ? 703 MAL C "O5'" 1 HETATM 7556 O "O6'" . MAL F 6 . ? -143.009 -141.093 168.616 1.00 97.57 ? 703 MAL C "O6'" 1 HETATM 7557 S S1 . MPO G 7 . ? -155.520 -140.557 161.923 1.00 150.45 ? 704 MPO C S1 1 HETATM 7558 O O1 . MPO G 7 . ? -156.514 -140.178 160.918 1.00 136.16 ? 704 MPO C O1 1 HETATM 7559 O O2 . MPO G 7 . ? -154.004 -140.267 161.296 1.00 124.17 ? 704 MPO C O2 1 HETATM 7560 O O4 . MPO G 7 . ? -152.192 -135.978 164.523 1.00 111.37 ? 704 MPO C O4 1 HETATM 7561 N N1 . MPO G 7 . ? -154.018 -136.292 162.517 1.00 104.64 ? 704 MPO C N1 1 HETATM 7562 C C1 . MPO G 7 . ? -155.776 -139.639 163.313 1.00 117.99 ? 704 MPO C C1 1 HETATM 7563 O O3 . MPO G 7 . ? -155.630 -141.976 162.262 1.00 132.11 ? 704 MPO C O3 1 HETATM 7564 C C2 . MPO G 7 . ? -155.676 -138.129 162.995 1.00 111.32 ? 704 MPO C C2 1 HETATM 7565 C C3 . MPO G 7 . ? -154.186 -137.728 162.837 1.00 108.70 ? 704 MPO C C3 1 HETATM 7566 C C4 . MPO G 7 . ? -152.616 -136.038 162.092 1.00 95.91 ? 704 MPO C C4 1 HETATM 7567 C C5 . MPO G 7 . ? -151.820 -135.404 163.245 1.00 108.65 ? 704 MPO C C5 1 HETATM 7568 C C6 . MPO G 7 . ? -153.549 -135.731 164.935 1.00 94.86 ? 704 MPO C C6 1 HETATM 7569 C C7 . MPO G 7 . ? -154.406 -135.472 163.694 1.00 107.15 ? 704 MPO C C7 1 HETATM 7570 C C1 . CLR H 8 . ? -139.112 -158.252 201.907 1.00 98.70 ? 705 CLR C C1 1 HETATM 7571 C C2 . CLR H 8 . ? -140.088 -159.325 202.381 1.00 96.07 ? 705 CLR C C2 1 HETATM 7572 C C3 . CLR H 8 . ? -141.071 -158.726 203.380 1.00 92.05 ? 705 CLR C C3 1 HETATM 7573 C C4 . CLR H 8 . ? -141.905 -157.688 202.637 1.00 92.74 ? 705 CLR C C4 1 HETATM 7574 C C5 . CLR H 8 . ? -141.102 -156.780 201.717 1.00 91.21 ? 705 CLR C C5 1 HETATM 7575 C C6 . CLR H 8 . ? -141.620 -155.577 201.438 1.00 87.01 ? 705 CLR C C6 1 HETATM 7576 C C7 . CLR H 8 . ? -140.731 -154.369 201.292 1.00 91.23 ? 705 CLR C C7 1 HETATM 7577 C C8 . CLR H 8 . ? -139.549 -154.729 200.413 1.00 90.53 ? 705 CLR C C8 1 HETATM 7578 C C9 . CLR H 8 . ? -138.848 -155.977 200.937 1.00 93.13 ? 705 CLR C C9 1 HETATM 7579 C C10 . CLR H 8 . ? -139.791 -157.180 201.064 1.00 94.57 ? 705 CLR C C10 1 HETATM 7580 C C11 . CLR H 8 . ? -137.610 -156.300 200.092 1.00 91.70 ? 705 CLR C C11 1 HETATM 7581 C C12 . CLR H 8 . ? -136.653 -155.109 199.908 1.00 92.81 ? 705 CLR C C12 1 HETATM 7582 C C13 . CLR H 8 . ? -137.406 -153.865 199.443 1.00 93.03 ? 705 CLR C C13 1 HETATM 7583 C C14 . CLR H 8 . ? -138.528 -153.609 200.424 1.00 88.46 ? 705 CLR C C14 1 HETATM 7584 C C15 . CLR H 8 . ? -139.020 -152.208 200.111 1.00 83.37 ? 705 CLR C C15 1 HETATM 7585 C C16 . CLR H 8 . ? -137.748 -151.471 199.684 1.00 85.08 ? 705 CLR C C16 1 HETATM 7586 C C17 . CLR H 8 . ? -136.669 -152.528 199.496 1.00 89.24 ? 705 CLR C C17 1 HETATM 7587 C C18 . CLR H 8 . ? -137.965 -154.107 198.042 1.00 85.23 ? 705 CLR C C18 1 HETATM 7588 C C19 . CLR H 8 . ? -140.084 -157.730 199.673 1.00 85.23 ? 705 CLR C C19 1 HETATM 7589 C C20 . CLR H 8 . ? -135.791 -152.164 198.307 1.00 89.68 ? 705 CLR C C20 1 HETATM 7590 C C21 . CLR H 8 . ? -134.613 -153.124 198.145 1.00 91.53 ? 705 CLR C C21 1 HETATM 7591 C C22 . CLR H 8 . ? -135.278 -150.732 198.490 1.00 86.27 ? 705 CLR C C22 1 HETATM 7592 C C23 . CLR H 8 . ? -134.101 -150.455 197.554 1.00 81.27 ? 705 CLR C C23 1 HETATM 7593 C C24 . CLR H 8 . ? -133.382 -149.173 197.942 1.00 78.97 ? 705 CLR C C24 1 HETATM 7594 C C25 . CLR H 8 . ? -132.804 -148.458 196.725 1.00 78.69 ? 705 CLR C C25 1 HETATM 7595 C C26 . CLR H 8 . ? -131.929 -147.277 197.141 1.00 75.52 ? 705 CLR C C26 1 HETATM 7596 C C27 . CLR H 8 . ? -133.927 -147.981 195.811 1.00 77.46 ? 705 CLR C C27 1 HETATM 7597 O O1 . CLR H 8 . ? -141.931 -159.739 203.952 1.00 83.04 ? 705 CLR C O1 1 HETATM 7598 N N . 1WE I 9 . ? -150.706 -142.384 196.513 1.00 77.31 ? 706 1WE C N 1 HETATM 7599 C CA . 1WE I 9 . ? -152.082 -142.925 196.472 1.00 78.46 ? 706 1WE C CA 1 HETATM 7600 C C . 1WE I 9 . ? -152.596 -142.904 197.905 1.00 75.96 ? 706 1WE C C 1 HETATM 7601 C CB . 1WE I 9 . ? -152.939 -142.058 195.544 1.00 79.55 ? 706 1WE C CB 1 HETATM 7602 C CG . 1WE I 9 . ? -154.158 -142.771 195.001 1.00 81.26 ? 706 1WE C CG 1 HETATM 7603 C CD1 . 1WE I 9 . ? -154.132 -143.261 193.697 1.00 84.18 ? 706 1WE C CD1 1 HETATM 7604 C CD2 . 1WE I 9 . ? -155.308 -142.921 195.775 1.00 78.82 ? 706 1WE C CD2 1 HETATM 7605 C CE1 . 1WE I 9 . ? -155.239 -143.922 193.166 1.00 79.15 ? 706 1WE C CE1 1 HETATM 7606 C CE2 . 1WE I 9 . ? -156.415 -143.580 195.240 1.00 84.89 ? 706 1WE C CE2 1 HETATM 7607 C CZ . 1WE I 9 . ? -156.385 -144.080 193.939 1.00 79.47 ? 706 1WE C CZ 1 HETATM 7608 C C8 . P4G J 10 . ? -180.009 -146.245 199.777 1.00 113.36 ? 707 P4G C C8 1 HETATM 7609 C C7 . P4G J 10 . ? -179.702 -144.990 199.019 1.00 121.58 ? 707 P4G C C7 1 HETATM 7610 O O4 . P4G J 10 . ? -180.888 -144.183 198.853 1.00 123.97 ? 707 P4G C O4 1 HETATM 7611 C C6 . P4G J 10 . ? -180.643 -142.787 198.536 1.00 120.44 ? 707 P4G C C6 1 HETATM 7612 C C5 . P4G J 10 . ? -179.601 -142.614 197.431 1.00 119.79 ? 707 P4G C C5 1 HETATM 7613 O O3 . P4G J 10 . ? -179.579 -141.209 197.072 1.00 123.44 ? 707 P4G C O3 1 HETATM 7614 C C4 . P4G J 10 . ? -179.376 -140.959 195.674 1.00 124.46 ? 707 P4G C C4 1 HETATM 7615 C C3 . P4G J 10 . ? -180.209 -139.707 195.231 1.00 120.27 ? 707 P4G C C3 1 HETATM 7616 O O2 . P4G J 10 . ? -179.685 -138.516 195.899 1.00 114.76 ? 707 P4G C O2 1 HETATM 7617 C C2 . P4G J 10 . ? -180.573 -137.381 195.860 1.00 116.83 ? 707 P4G C C2 1 HETATM 7618 C C1 . P4G J 10 . ? -181.715 -137.561 196.839 1.00 111.37 ? 707 P4G C C1 1 HETATM 7619 H H81 . P4G J 10 . ? -179.197 -146.762 199.888 1.00 136.04 ? 707 P4G C H81 1 HETATM 7620 H H82 . P4G J 10 . ? -180.664 -146.769 199.285 1.00 136.04 ? 707 P4G C H82 1 HETATM 7621 H H83 . P4G J 10 . ? -180.373 -146.010 200.663 1.00 136.04 ? 707 P4G C H83 1 HETATM 7622 H H71 . P4G J 10 . ? -179.350 -145.217 198.155 1.00 145.90 ? 707 P4G C H71 1 HETATM 7623 H H72 . P4G J 10 . ? -179.048 -144.488 199.501 1.00 145.90 ? 707 P4G C H72 1 HETATM 7624 H H61 . P4G J 10 . ? -180.326 -142.328 199.347 1.00 144.53 ? 707 P4G C H61 1 HETATM 7625 H H62 . P4G J 10 . ? -181.485 -142.375 198.247 1.00 144.53 ? 707 P4G C H62 1 HETATM 7626 H H51 . P4G J 10 . ? -178.715 -142.888 197.760 1.00 143.74 ? 707 P4G C H51 1 HETATM 7627 H H52 . P4G J 10 . ? -179.850 -143.155 196.648 1.00 143.74 ? 707 P4G C H52 1 HETATM 7628 H H41 . P4G J 10 . ? -179.666 -141.741 195.158 1.00 149.35 ? 707 P4G C H41 1 HETATM 7629 H H42 . P4G J 10 . ? -178.414 -140.792 195.507 1.00 149.35 ? 707 P4G C H42 1 HETATM 7630 H H31 . P4G J 10 . ? -180.140 -139.592 194.246 1.00 144.33 ? 707 P4G C H31 1 HETATM 7631 H H32 . P4G J 10 . ? -181.159 -139.836 195.484 1.00 144.33 ? 707 P4G C H32 1 HETATM 7632 H H21 . P4G J 10 . ? -180.066 -136.564 196.097 1.00 140.20 ? 707 P4G C H21 1 HETATM 7633 H H22 . P4G J 10 . ? -180.935 -137.286 194.955 1.00 140.20 ? 707 P4G C H22 1 HETATM 7634 H H11 . P4G J 10 . ? -182.180 -138.393 196.646 1.00 133.65 ? 707 P4G C H11 1 HETATM 7635 H H12 . P4G J 10 . ? -182.341 -136.807 196.754 1.00 133.65 ? 707 P4G C H12 1 HETATM 7636 H H13 . P4G J 10 . ? -181.362 -137.589 197.749 1.00 133.65 ? 707 P4G C H13 1 HETATM 7637 C C8 . P4G K 10 . ? -172.089 -121.231 178.905 1.00 111.26 ? 708 P4G C C8 1 HETATM 7638 C C7 . P4G K 10 . ? -171.977 -122.231 177.800 1.00 109.51 ? 708 P4G C C7 1 HETATM 7639 O O4 . P4G K 10 . ? -170.696 -122.077 177.153 1.00 117.76 ? 708 P4G C O4 1 HETATM 7640 C C6 . P4G K 10 . ? -170.434 -123.126 176.172 1.00 112.59 ? 708 P4G C C6 1 HETATM 7641 C C5 . P4G K 10 . ? -169.398 -122.636 175.166 1.00 113.59 ? 708 P4G C C5 1 HETATM 7642 O O3 . P4G K 10 . ? -168.310 -121.946 175.842 1.00 117.82 ? 708 P4G C O3 1 HETATM 7643 C C4 . P4G K 10 . ? -168.031 -120.664 175.254 1.00 116.07 ? 708 P4G C C4 1 HETATM 7644 C C3 . P4G K 10 . ? -166.938 -119.928 176.118 1.00 117.43 ? 708 P4G C C3 1 HETATM 7645 O O2 . P4G K 10 . ? -165.727 -119.610 175.364 1.00 115.27 ? 708 P4G C O2 1 HETATM 7646 C C2 . P4G K 10 . ? -165.868 -118.683 174.257 1.00 116.01 ? 708 P4G C C2 1 HETATM 7647 C C1 . P4G K 10 . ? -164.539 -118.512 173.549 1.00 110.83 ? 708 P4G C C1 1 HETATM 7648 H H81 . P4G K 10 . ? -172.027 -120.336 178.539 1.00 133.51 ? 708 P4G C H81 1 HETATM 7649 H H82 . P4G K 10 . ? -171.369 -121.371 179.544 1.00 133.51 ? 708 P4G C H82 1 HETATM 7650 H H83 . P4G K 10 . ? -172.957 -121.342 179.359 1.00 133.51 ? 708 P4G C H83 1 HETATM 7651 H H71 . P4G K 10 . ? -172.058 -123.122 178.149 1.00 131.42 ? 708 P4G C H71 1 HETATM 7652 H H72 . P4G K 10 . ? -172.672 -122.076 177.163 1.00 131.42 ? 708 P4G C H72 1 HETATM 7653 H H61 . P4G K 10 . ? -171.268 -123.349 175.701 1.00 135.11 ? 708 P4G C H61 1 HETATM 7654 H H62 . P4G K 10 . ? -170.094 -123.923 176.631 1.00 135.11 ? 708 P4G C H62 1 HETATM 7655 H H51 . P4G K 10 . ? -169.828 -122.019 174.531 1.00 136.31 ? 708 P4G C H51 1 HETATM 7656 H H52 . P4G K 10 . ? -169.035 -123.407 174.673 1.00 136.31 ? 708 P4G C H52 1 HETATM 7657 H H41 . P4G K 10 . ? -167.696 -120.788 174.341 1.00 139.29 ? 708 P4G C H41 1 HETATM 7658 H H42 . P4G K 10 . ? -168.859 -120.123 175.233 1.00 139.29 ? 708 P4G C H42 1 HETATM 7659 H H31 . P4G K 10 . ? -166.692 -120.509 176.887 1.00 140.92 ? 708 P4G C H31 1 HETATM 7660 H H32 . P4G K 10 . ? -167.325 -119.084 176.467 1.00 140.92 ? 708 P4G C H32 1 HETATM 7661 H H21 . P4G K 10 . ? -166.171 -117.806 174.602 1.00 139.21 ? 708 P4G C H21 1 HETATM 7662 H H22 . P4G K 10 . ? -166.531 -119.032 173.625 1.00 139.21 ? 708 P4G C H22 1 HETATM 7663 H H11 . P4G K 10 . ? -164.269 -119.360 173.155 1.00 133.00 ? 708 P4G C H11 1 HETATM 7664 H H12 . P4G K 10 . ? -163.859 -118.219 174.196 1.00 133.00 ? 708 P4G C H12 1 HETATM 7665 H H13 . P4G K 10 . ? -164.629 -117.841 172.845 1.00 133.00 ? 708 P4G C H13 1 HETATM 7666 NA NA . NA L 11 . ? -147.317 -141.949 198.424 1.00 72.67 ? 709 NA C NA 1 HETATM 7667 NA NA . NA M 11 . ? -148.330 -147.353 192.632 1.00 70.25 ? 710 NA C NA 1 HETATM 7668 CL CL . CL N 12 . ? -144.584 -138.718 200.789 1.00 77.42 ? 711 CL C CL 1 HETATM 7669 O O . HOH O 13 . ? -145.176 -148.959 192.311 1.00 74.48 ? 801 HOH C O 1 HETATM 7670 O O . HOH O 13 . ? -152.738 -156.793 194.637 1.00 72.77 ? 802 HOH C O 1 HETATM 7671 O O . HOH O 13 . ? -135.478 -132.218 168.982 1.00 74.35 ? 803 HOH C O 1 HETATM 7672 O O . HOH O 13 . ? -131.653 -139.480 188.746 1.00 78.19 ? 804 HOH C O 1 HETATM 7673 O O . HOH O 13 . ? -148.759 -140.390 196.733 1.00 76.88 ? 805 HOH C O 1 HETATM 7674 O O . HOH O 13 . ? -157.741 -146.945 201.220 1.00 79.98 ? 806 HOH C O 1 HETATM 7675 O O . HOH O 13 . ? -140.385 -123.749 185.763 1.00 85.82 ? 807 HOH C O 1 HETATM 7676 O O . HOH O 13 . ? -149.647 -128.963 168.178 1.00 79.11 ? 808 HOH C O 1 HETATM 7677 O O . HOH O 13 . ? -160.678 -160.588 222.368 1.00 73.36 ? 809 HOH C O 1 HETATM 7678 O O . HOH O 13 . ? -149.061 -129.501 180.058 1.00 78.36 ? 810 HOH C O 1 HETATM 7679 O O . HOH O 13 . ? -146.071 -129.573 186.254 1.00 64.29 ? 811 HOH C O 1 HETATM 7680 O O . HOH O 13 . ? -125.034 -143.069 173.343 1.00 74.11 ? 812 HOH C O 1 HETATM 7681 O O . HOH O 13 . ? -149.376 -134.216 193.774 1.00 65.48 ? 813 HOH C O 1 HETATM 7682 O O . HOH O 13 . ? -154.973 -138.971 193.660 1.00 71.51 ? 814 HOH C O 1 HETATM 7683 O O . HOH O 13 . ? -127.982 -123.881 198.516 1.00 73.72 ? 815 HOH C O 1 HETATM 7684 O O . HOH O 13 . ? -123.154 -126.473 204.061 1.00 93.66 ? 816 HOH C O 1 HETATM 7685 O O . HOH P 13 . ? -142.558 -192.702 248.946 1.00 85.76 ? 301 HOH L O 1 HETATM 7686 O O . HOH P 13 . ? -153.029 -190.477 258.885 1.00 81.80 ? 302 HOH L O 1 HETATM 7687 O O . HOH P 13 . ? -142.796 -165.565 245.141 1.00 58.77 ? 303 HOH L O 1 HETATM 7688 O O . HOH P 13 . ? -144.826 -164.696 218.384 1.00 71.64 ? 304 HOH L O 1 HETATM 7689 O O . HOH P 13 . ? -165.906 -199.496 264.235 1.00 97.58 ? 305 HOH L O 1 HETATM 7690 O O . HOH P 13 . ? -143.530 -181.918 220.295 1.00 89.18 ? 306 HOH L O 1 HETATM 7691 O O . HOH P 13 . ? -141.578 -174.030 214.976 1.00 69.29 ? 307 HOH L O 1 HETATM 7692 O O . HOH P 13 . ? -141.228 -169.307 218.309 1.00 72.99 ? 308 HOH L O 1 HETATM 7693 O O . HOH P 13 . ? -148.224 -169.088 217.073 1.00 83.48 ? 309 HOH L O 1 HETATM 7694 O O . HOH Q 13 . ? -158.071 -153.176 245.377 1.00 81.63 ? 301 HOH H O 1 HETATM 7695 O O . HOH Q 13 . ? -154.892 -186.984 256.271 1.00 77.30 ? 302 HOH H O 1 HETATM 7696 O O . HOH Q 13 . ? -159.682 -178.570 222.320 1.00 89.02 ? 303 HOH H O 1 HETATM 7697 O O . HOH Q 13 . ? -139.840 -171.298 265.598 1.00 92.86 ? 304 HOH H O 1 HETATM 7698 O O . HOH Q 13 . ? -164.071 -168.915 248.480 1.00 71.77 ? 305 HOH H O 1 HETATM 7699 O O . HOH Q 13 . ? -155.309 -160.306 243.957 1.00 79.03 ? 306 HOH H O 1 HETATM 7700 O O . HOH Q 13 . ? -151.454 -182.624 233.517 1.00 77.03 ? 307 HOH H O 1 HETATM 7701 O O . HOH Q 13 . ? -167.028 -167.253 249.208 1.00 74.30 ? 308 HOH H O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ASP 1 25 25 ASP ASP C . n A 1 2 GLU 2 26 26 GLU GLU C . n A 1 3 ARG 3 27 27 ARG ARG C . n A 1 4 GLU 4 28 28 GLU GLU C . n A 1 5 THR 5 29 29 THR THR C . n A 1 6 TRP 6 30 30 TRP TRP C . n A 1 7 SER 7 31 31 SER SER C . n A 1 8 GLY 8 32 32 GLY GLY C . n A 1 9 LYS 9 33 33 LYS LYS C . n A 1 10 VAL 10 34 34 VAL VAL C . n A 1 11 ASP 11 35 35 ASP ASP C . n A 1 12 PHE 12 36 36 PHE PHE C . n A 1 13 LEU 13 37 37 LEU LEU C . n A 1 14 LEU 14 38 38 LEU LEU C . n A 1 15 SER 15 39 39 SER SER C . n A 1 16 VAL 16 40 40 VAL VAL C . n A 1 17 ILE 17 41 41 ILE ILE C . n A 1 18 GLY 18 42 42 GLY GLY C . n A 1 19 PHE 19 43 43 PHE PHE C . n A 1 20 ALA 20 44 44 ALA ALA C . n A 1 21 VAL 21 45 45 VAL VAL C . n A 1 22 ASP 22 46 46 ASP ASP C . n A 1 23 LEU 23 47 47 LEU LEU C . n A 1 24 ALA 24 48 48 ALA ALA C . n A 1 25 ASN 25 49 49 ASN ASN C . n A 1 26 VAL 26 50 50 VAL VAL C . n A 1 27 TRP 27 51 51 TRP TRP C . n A 1 28 ARG 28 52 52 ARG ARG C . n A 1 29 PHE 29 53 53 PHE PHE C . n A 1 30 PRO 30 54 54 PRO PRO C . n A 1 31 TYR 31 55 55 TYR TYR C . n A 1 32 LEU 32 56 56 LEU LEU C . n A 1 33 CYS 33 57 57 CYS CYS C . n A 1 34 TYR 34 58 58 TYR TYR C . n A 1 35 LYS 35 59 59 LYS LYS C . n A 1 36 ASN 36 60 60 ASN ASN C . n A 1 37 GLY 37 61 61 GLY GLY C . n A 1 38 GLY 38 62 62 GLY GLY C . n A 1 39 GLY 39 63 63 GLY GLY C . n A 1 40 ALA 40 64 64 ALA ALA C . n A 1 41 PHE 41 65 65 PHE PHE C . n A 1 42 LEU 42 66 66 LEU LEU C . n A 1 43 VAL 43 67 67 VAL VAL C . n A 1 44 PRO 44 68 68 PRO PRO C . n A 1 45 TYR 45 69 69 TYR TYR C . n A 1 46 GLY 46 70 70 GLY GLY C . n A 1 47 ILE 47 71 71 ILE ILE C . n A 1 48 MET 48 72 72 MET MET C . n A 1 49 LEU 49 73 73 LEU LEU C . n A 1 50 ALA 50 74 74 ALA ALA C . n A 1 51 VAL 51 75 75 VAL VAL C . n A 1 52 GLY 52 76 76 GLY GLY C . n A 1 53 GLY 53 77 77 GLY GLY C . n A 1 54 ILE 54 78 78 ILE ILE C . n A 1 55 PRO 55 79 79 PRO PRO C . n A 1 56 LEU 56 80 80 LEU LEU C . n A 1 57 PHE 57 81 81 PHE PHE C . n A 1 58 TYR 58 82 82 TYR TYR C . n A 1 59 MET 59 83 83 MET MET C . n A 1 60 GLU 60 84 84 GLU GLU C . n A 1 61 LEU 61 85 85 LEU LEU C . n A 1 62 ALA 62 86 86 ALA ALA C . n A 1 63 LEU 63 87 87 LEU LEU C . n A 1 64 GLY 64 88 88 GLY GLY C . n A 1 65 GLN 65 89 89 GLN GLN C . n A 1 66 HIS 66 90 90 HIS HIS C . n A 1 67 ASN 67 91 91 ASN ASN C . n A 1 68 ARG 68 92 92 ARG ARG C . n A 1 69 LYS 69 93 93 LYS LYS C . n A 1 70 GLY 70 94 94 GLY GLY C . n A 1 71 ALA 71 95 95 ALA ALA C . n A 1 72 ILE 72 96 96 ILE ILE C . n A 1 73 THR 73 97 97 THR THR C . n A 1 74 CYS 74 98 98 CYS CYS C . n A 1 75 TRP 75 99 99 TRP TRP C . n A 1 76 GLY 76 100 100 GLY GLY C . n A 1 77 ARG 77 101 101 ARG ARG C . n A 1 78 LEU 78 102 102 LEU LEU C . n A 1 79 VAL 79 103 103 VAL VAL C . n A 1 80 PRO 80 104 104 PRO PRO C . n A 1 81 LEU 81 105 105 LEU LEU C . n A 1 82 PHE 82 106 106 PHE PHE C . n A 1 83 LYS 83 107 107 LYS LYS C . n A 1 84 GLY 84 108 108 GLY GLY C . n A 1 85 ILE 85 109 109 ILE ILE C . n A 1 86 GLY 86 110 110 GLY GLY C . n A 1 87 TYR 87 111 111 TYR TYR C . n A 1 88 ALA 88 112 112 ALA ALA C . n A 1 89 VAL 89 113 113 VAL VAL C . n A 1 90 VAL 90 114 114 VAL VAL C . n A 1 91 LEU 91 115 115 LEU LEU C . n A 1 92 ILE 92 116 116 ILE ILE C . n A 1 93 ALA 93 117 117 ALA ALA C . n A 1 94 PHE 94 118 118 PHE PHE C . n A 1 95 TYR 95 119 119 TYR TYR C . n A 1 96 VAL 96 120 120 VAL VAL C . n A 1 97 ASP 97 121 121 ASP ASP C . n A 1 98 PHE 98 122 122 PHE PHE C . n A 1 99 TYR 99 123 123 TYR TYR C . n A 1 100 TYR 100 124 124 TYR TYR C . n A 1 101 ASN 101 125 125 ASN ASN C . n A 1 102 VAL 102 126 126 VAL VAL C . n A 1 103 ILE 103 127 127 ILE ILE C . n A 1 104 ILE 104 128 128 ILE ILE C . n A 1 105 ALA 105 129 129 ALA ALA C . n A 1 106 TRP 106 130 130 TRP TRP C . n A 1 107 SER 107 131 131 SER SER C . n A 1 108 LEU 108 132 132 LEU LEU C . n A 1 109 ARG 109 133 133 ARG ARG C . n A 1 110 PHE 110 134 134 PHE PHE C . n A 1 111 PHE 111 135 135 PHE PHE C . n A 1 112 PHE 112 136 136 PHE PHE C . n A 1 113 ALA 113 137 137 ALA ALA C . n A 1 114 SER 114 138 138 SER SER C . n A 1 115 PHE 115 139 139 PHE PHE C . n A 1 116 THR 116 140 140 THR THR C . n A 1 117 ASN 117 141 141 ASN ASN C . n A 1 118 SER 118 142 142 SER SER C . n A 1 119 LEU 119 143 143 LEU LEU C . n A 1 120 PRO 120 144 144 PRO PRO C . n A 1 121 TRP 121 145 145 TRP TRP C . n A 1 122 THR 122 146 146 THR THR C . n A 1 123 SER 123 147 147 SER SER C . n A 1 124 CYS 124 148 148 CYS CYS C . n A 1 125 ASN 125 149 149 ASN ASN C . n A 1 126 ASN 126 150 150 ASN ASN C . n A 1 127 ILE 127 151 151 ILE ILE C . n A 1 128 TRP 128 152 152 TRP TRP C . n A 1 129 ASN 129 153 153 ASN ASN C . n A 1 130 THR 130 154 154 THR THR C . n A 1 131 PRO 131 155 155 PRO PRO C . n A 1 132 ASN 132 156 156 ASN ASN C . n A 1 133 CYS 133 157 157 CYS CYS C . n A 1 134 ARG 134 158 158 ARG ARG C . n A 1 135 PRO 135 159 159 PRO PRO C . n A 1 136 PHE 136 160 160 PHE PHE C . n A 1 137 GLU 137 161 161 GLU GLU C . n A 1 138 GLY 138 203 203 GLY GLY C . n A 1 139 HIS 139 204 204 HIS HIS C . n A 1 140 VAL 140 205 205 VAL VAL C . n A 1 141 GLU 141 206 206 GLU GLU C . n A 1 142 GLY 142 207 207 GLY GLY C . n A 1 143 PHE 143 208 208 PHE PHE C . n A 1 144 GLN 144 209 209 GLN GLN C . n A 1 145 SER 145 210 210 SER SER C . n A 1 146 ALA 146 211 211 ALA ALA C . n A 1 147 ALA 147 212 212 ALA ALA C . n A 1 148 SER 148 213 213 SER SER C . n A 1 149 GLU 149 214 214 GLU GLU C . n A 1 150 TYR 150 215 215 TYR TYR C . n A 1 151 PHE 151 216 216 PHE PHE C . n A 1 152 ASN 152 217 217 ASN ASN C . n A 1 153 ARG 153 218 218 ARG ARG C . n A 1 154 TYR 154 219 219 TYR TYR C . n A 1 155 ILE 155 220 220 ILE ILE C . n A 1 156 LEU 156 221 221 LEU LEU C . n A 1 157 GLU 157 222 222 GLU GLU C . n A 1 158 LEU 158 223 223 LEU LEU C . n A 1 159 ASN 159 224 224 ASN ASN C . n A 1 160 ARG 160 225 225 ARG ARG C . n A 1 161 SER 161 226 226 SER SER C . n A 1 162 GLU 162 227 227 GLU GLU C . n A 1 163 GLY 163 228 228 GLY GLY C . n A 1 164 ILE 164 229 229 ILE ILE C . n A 1 165 HIS 165 230 230 HIS HIS C . n A 1 166 ASP 166 231 231 ASP ASP C . n A 1 167 LEU 167 232 232 LEU LEU C . n A 1 168 GLY 168 233 233 GLY GLY C . n A 1 169 ALA 169 234 234 ALA ALA C . n A 1 170 ILE 170 235 235 ILE ILE C . n A 1 171 LYS 171 236 236 LYS LYS C . n A 1 172 TRP 172 237 237 TRP TRP C . n A 1 173 ASP 173 238 238 ASP ASP C . n A 1 174 MET 174 239 239 MET MET C . n A 1 175 ALA 175 240 240 ALA ALA C . n A 1 176 LEU 176 241 241 LEU LEU C . n A 1 177 CYS 177 242 242 CYS CYS C . n A 1 178 LEU 178 243 243 LEU LEU C . n A 1 179 LEU 179 244 244 LEU LEU C . n A 1 180 ILE 180 245 245 ILE ILE C . n A 1 181 VAL 181 246 246 VAL VAL C . n A 1 182 TYR 182 247 247 TYR TYR C . n A 1 183 LEU 183 248 248 LEU LEU C . n A 1 184 ILE 184 249 249 ILE ILE C . n A 1 185 CYS 185 250 250 CYS CYS C . n A 1 186 TYR 186 251 251 TYR TYR C . n A 1 187 PHE 187 252 252 PHE PHE C . n A 1 188 SER 188 253 253 SER SER C . n A 1 189 LEU 189 254 254 LEU LEU C . n A 1 190 TRP 190 255 255 TRP TRP C . n A 1 191 LYS 191 256 256 LYS LYS C . n A 1 192 GLY 192 257 257 GLY GLY C . n A 1 193 ILE 193 258 258 ILE ILE C . n A 1 194 SER 194 259 259 SER SER C . n A 1 195 THR 195 260 260 THR THR C . n A 1 196 SER 196 261 261 SER SER C . n A 1 197 GLY 197 262 262 GLY GLY C . n A 1 198 LYS 198 263 263 LYS LYS C . n A 1 199 VAL 199 264 264 VAL VAL C . n A 1 200 VAL 200 265 265 VAL VAL C . n A 1 201 TRP 201 266 266 TRP TRP C . n A 1 202 PHE 202 267 267 PHE PHE C . n A 1 203 THR 203 268 268 THR THR C . n A 1 204 ALA 204 269 269 ALA ALA C . n A 1 205 LEU 205 270 270 LEU LEU C . n A 1 206 PHE 206 271 271 PHE PHE C . n A 1 207 PRO 207 272 272 PRO PRO C . n A 1 208 TYR 208 273 273 TYR TYR C . n A 1 209 ALA 209 274 274 ALA ALA C . n A 1 210 VAL 210 275 275 VAL VAL C . n A 1 211 LEU 211 276 276 LEU LEU C . n A 1 212 LEU 212 277 277 LEU LEU C . n A 1 213 ILE 213 278 278 ILE ILE C . n A 1 214 LEU 214 279 279 LEU LEU C . n A 1 215 LEU 215 280 280 LEU LEU C . n A 1 216 ILE 216 281 281 ILE ILE C . n A 1 217 ARG 217 282 282 ARG ARG C . n A 1 218 GLY 218 283 283 GLY GLY C . n A 1 219 LEU 219 284 284 LEU LEU C . n A 1 220 THR 220 285 285 THR THR C . n A 1 221 LEU 221 286 286 LEU LEU C . n A 1 222 PRO 222 287 287 PRO PRO C . n A 1 223 GLY 223 288 288 GLY GLY C . n A 1 224 SER 224 289 289 SER SER C . n A 1 225 PHE 225 290 290 PHE PHE C . n A 1 226 LEU 226 291 291 LEU LEU C . n A 1 227 GLY 227 292 292 GLY GLY C . n A 1 228 ILE 228 293 293 ILE ILE C . n A 1 229 GLN 229 294 294 GLN GLN C . n A 1 230 TYR 230 295 295 TYR TYR C . n A 1 231 TYR 231 296 296 TYR TYR C . n A 1 232 LEU 232 297 297 LEU LEU C . n A 1 233 THR 233 298 298 THR THR C . n A 1 234 PRO 234 299 299 PRO PRO C . n A 1 235 ASN 235 300 300 ASN ASN C . n A 1 236 PHE 236 301 301 PHE PHE C . n A 1 237 SER 237 302 302 SER SER C . n A 1 238 ALA 238 303 303 ALA ALA C . n A 1 239 ILE 239 304 304 ILE ILE C . n A 1 240 TYR 240 305 305 TYR TYR C . n A 1 241 LYS 241 306 306 LYS LYS C . n A 1 242 ALA 242 307 307 ALA ALA C . n A 1 243 GLU 243 308 308 GLU GLU C . n A 1 244 VAL 244 309 309 VAL VAL C . n A 1 245 TRP 245 310 310 TRP TRP C . n A 1 246 VAL 246 311 311 VAL VAL C . n A 1 247 ASP 247 312 312 ASP ASP C . n A 1 248 ALA 248 313 313 ALA ALA C . n A 1 249 ALA 249 314 314 ALA ALA C . n A 1 250 THR 250 315 315 THR THR C . n A 1 251 GLN 251 316 316 GLN GLN C . n A 1 252 VAL 252 317 317 VAL VAL C . n A 1 253 PHE 253 318 318 PHE PHE C . n A 1 254 PHE 254 319 319 PHE PHE C . n A 1 255 SER 255 320 320 SER SER C . n A 1 256 LEU 256 321 321 LEU LEU C . n A 1 257 GLY 257 322 322 GLY GLY C . n A 1 258 PRO 258 323 323 PRO PRO C . n A 1 259 GLY 259 324 324 GLY GLY C . n A 1 260 PHE 260 325 325 PHE PHE C . n A 1 261 GLY 261 326 326 GLY GLY C . n A 1 262 VAL 262 327 327 VAL VAL C . n A 1 263 LEU 263 328 328 LEU LEU C . n A 1 264 LEU 264 329 329 LEU LEU C . n A 1 265 ALA 265 330 330 ALA ALA C . n A 1 266 TYR 266 331 331 TYR TYR C . n A 1 267 ALA 267 332 332 ALA ALA C . n A 1 268 SER 268 333 333 SER SER C . n A 1 269 TYR 269 334 334 TYR TYR C . n A 1 270 ASN 270 335 335 ASN ASN C . n A 1 271 LYS 271 336 336 LYS LYS C . n A 1 272 TYR 272 337 337 TYR TYR C . n A 1 273 HIS 273 338 338 HIS HIS C . n A 1 274 ASN 274 339 339 ASN ASN C . n A 1 275 ASN 275 340 340 ASN ASN C . n A 1 276 VAL 276 341 341 VAL VAL C . n A 1 277 TYR 277 342 342 TYR TYR C . n A 1 278 LYS 278 343 343 LYS LYS C . n A 1 279 ASP 279 344 344 ASP ASP C . n A 1 280 ALA 280 345 345 ALA ALA C . n A 1 281 LEU 281 346 346 LEU LEU C . n A 1 282 LEU 282 347 347 LEU LEU C . n A 1 283 THR 283 348 348 THR THR C . n A 1 284 SER 284 349 349 SER SER C . n A 1 285 PHE 285 350 350 PHE PHE C . n A 1 286 ILE 286 351 351 ILE ILE C . n A 1 287 ASN 287 352 352 ASN ASN C . n A 1 288 SER 288 353 353 SER SER C . n A 1 289 ALA 289 354 354 ALA ALA C . n A 1 290 THR 290 355 355 THR THR C . n A 1 291 SER 291 356 356 SER SER C . n A 1 292 PHE 292 357 357 PHE PHE C . n A 1 293 ILE 293 358 358 ILE ILE C . n A 1 294 ALA 294 359 359 ALA ALA C . n A 1 295 GLY 295 360 360 GLY GLY C . n A 1 296 PHE 296 361 361 PHE PHE C . n A 1 297 VAL 297 362 362 VAL VAL C . n A 1 298 ILE 298 363 363 ILE ILE C . n A 1 299 PHE 299 364 364 PHE PHE C . n A 1 300 SER 300 365 365 SER SER C . n A 1 301 VAL 301 366 366 VAL VAL C . n A 1 302 LEU 302 367 367 LEU LEU C . n A 1 303 GLY 303 368 368 GLY GLY C . n A 1 304 TYR 304 369 369 TYR TYR C . n A 1 305 MET 305 370 370 MET MET C . n A 1 306 ALA 306 371 371 ALA ALA C . n A 1 307 HIS 307 372 372 HIS HIS C . n A 1 308 THR 308 373 373 THR THR C . n A 1 309 LEU 309 374 374 LEU LEU C . n A 1 310 GLY 310 375 375 GLY GLY C . n A 1 311 VAL 311 376 376 VAL VAL C . n A 1 312 ARG 312 377 377 ARG ARG C . n A 1 313 ILE 313 378 378 ILE ILE C . n A 1 314 GLU 314 379 379 GLU GLU C . n A 1 315 ASP 315 380 380 ASP ASP C . n A 1 316 VAL 316 381 381 VAL VAL C . n A 1 317 ALA 317 382 382 ALA ALA C . n A 1 318 THR 318 383 383 THR THR C . n A 1 319 GLU 319 384 384 GLU GLU C . n A 1 320 GLY 320 385 385 GLY GLY C . n A 1 321 PRO 321 386 386 PRO PRO C . n A 1 322 GLY 322 387 387 GLY GLY C . n A 1 323 LEU 323 388 388 LEU LEU C . n A 1 324 VAL 324 389 389 VAL VAL C . n A 1 325 PHE 325 390 390 PHE PHE C . n A 1 326 VAL 326 391 391 VAL VAL C . n A 1 327 VAL 327 392 392 VAL VAL C . n A 1 328 TYR 328 393 393 TYR TYR C . n A 1 329 PRO 329 394 394 PRO PRO C . n A 1 330 ALA 330 395 395 ALA ALA C . n A 1 331 ALA 331 396 396 ALA ALA C . n A 1 332 ILE 332 397 397 ILE ILE C . n A 1 333 ALA 333 398 398 ALA ALA C . n A 1 334 THR 334 399 399 THR THR C . n A 1 335 MET 335 400 400 MET MET C . n A 1 336 PRO 336 401 401 PRO PRO C . n A 1 337 ALA 337 402 402 ALA ALA C . n A 1 338 SER 338 403 403 SER SER C . n A 1 339 THR 339 404 404 THR THR C . n A 1 340 PHE 340 405 405 PHE PHE C . n A 1 341 TRP 341 406 406 TRP TRP C . n A 1 342 ALA 342 407 407 ALA ALA C . n A 1 343 LEU 343 408 408 LEU LEU C . n A 1 344 ILE 344 409 409 ILE ILE C . n A 1 345 PHE 345 410 410 PHE PHE C . n A 1 346 PHE 346 411 411 PHE PHE C . n A 1 347 MET 347 412 412 MET MET C . n A 1 348 MET 348 413 413 MET MET C . n A 1 349 LEU 349 414 414 LEU LEU C . n A 1 350 ALA 350 415 415 ALA ALA C . n A 1 351 THR 351 416 416 THR THR C . n A 1 352 LEU 352 417 417 LEU LEU C . n A 1 353 GLY 353 418 418 GLY GLY C . n A 1 354 LEU 354 419 419 LEU LEU C . n A 1 355 ASP 355 420 420 ASP ASP C . n A 1 356 SER 356 421 421 SER SER C . n A 1 357 SER 357 422 422 SER SER C . n A 1 358 PHE 358 423 423 PHE PHE C . n A 1 359 GLY 359 424 424 GLY GLY C . n A 1 360 GLY 360 425 425 GLY GLY C . n A 1 361 SER 361 426 426 SER SER C . n A 1 362 GLU 362 427 427 GLU GLU C . n A 1 363 ALA 363 428 428 ALA ALA C . n A 1 364 ILE 364 429 429 ILE ILE C . n A 1 365 ILE 365 430 430 ILE ILE C . n A 1 366 THR 366 431 431 THR THR C . n A 1 367 ALA 367 432 432 ALA ALA C . n A 1 368 LEU 368 433 433 LEU LEU C . n A 1 369 SER 369 434 434 SER SER C . n A 1 370 ASP 370 435 435 ASP ASP C . n A 1 371 GLU 371 436 436 GLU GLU C . n A 1 372 PHE 372 437 437 PHE PHE C . n A 1 373 PRO 373 438 438 PRO PRO C . n A 1 374 LYS 374 439 439 LYS LYS C . n A 1 375 ILE 375 440 440 ILE ILE C . n A 1 376 LYS 376 441 441 LYS LYS C . n A 1 377 ARG 377 442 442 ARG ARG C . n A 1 378 ASN 378 443 443 ASN ASN C . n A 1 379 ARG 379 444 444 ARG ARG C . n A 1 380 GLU 380 445 445 GLU GLU C . n A 1 381 LEU 381 446 446 LEU LEU C . n A 1 382 PHE 382 447 447 PHE PHE C . n A 1 383 VAL 383 448 448 VAL VAL C . n A 1 384 ALA 384 449 449 ALA ALA C . n A 1 385 GLY 385 450 450 GLY GLY C . n A 1 386 LEU 386 451 451 LEU LEU C . n A 1 387 PHE 387 452 452 PHE PHE C . n A 1 388 SER 388 453 453 SER SER C . n A 1 389 LEU 389 454 454 LEU LEU C . n A 1 390 TYR 390 455 455 TYR TYR C . n A 1 391 PHE 391 456 456 PHE PHE C . n A 1 392 VAL 392 457 457 VAL VAL C . n A 1 393 VAL 393 458 458 VAL VAL C . n A 1 394 GLY 394 459 459 GLY GLY C . n A 1 395 LEU 395 460 460 LEU LEU C . n A 1 396 ALA 396 461 461 ALA ALA C . n A 1 397 SER 397 462 462 SER SER C . n A 1 398 CYS 398 463 463 CYS CYS C . n A 1 399 THR 399 464 464 THR THR C . n A 1 400 GLN 400 465 465 GLN GLN C . n A 1 401 GLY 401 466 466 GLY GLY C . n A 1 402 GLY 402 467 467 GLY GLY C . n A 1 403 PHE 403 468 468 PHE PHE C . n A 1 404 TYR 404 469 469 TYR TYR C . n A 1 405 PHE 405 470 470 PHE PHE C . n A 1 406 PHE 406 471 471 PHE PHE C . n A 1 407 HIS 407 472 472 HIS HIS C . n A 1 408 LEU 408 473 473 LEU LEU C . n A 1 409 LEU 409 474 474 LEU LEU C . n A 1 410 ASP 410 475 475 ASP ASP C . n A 1 411 ARG 411 476 476 ARG ARG C . n A 1 412 TYR 412 477 477 TYR TYR C . n A 1 413 ALA 413 478 478 ALA ALA C . n A 1 414 ALA 414 479 479 ALA ALA C . n A 1 415 GLY 415 480 480 GLY GLY C . n A 1 416 TYR 416 481 481 TYR TYR C . n A 1 417 SER 417 482 482 SER SER C . n A 1 418 ILE 418 483 483 ILE ILE C . n A 1 419 LEU 419 484 484 LEU LEU C . n A 1 420 VAL 420 485 485 VAL VAL C . n A 1 421 ALA 421 486 486 ALA ALA C . n A 1 422 VAL 422 487 487 VAL VAL C . n A 1 423 PHE 423 488 488 PHE PHE C . n A 1 424 PHE 424 489 489 PHE PHE C . n A 1 425 GLU 425 490 490 GLU GLU C . n A 1 426 ALA 426 491 491 ALA ALA C . n A 1 427 ILE 427 492 492 ILE ILE C . n A 1 428 ALA 428 493 493 ALA ALA C . n A 1 429 VAL 429 494 494 VAL VAL C . n A 1 430 SER 430 495 495 SER SER C . n A 1 431 TRP 431 496 496 TRP TRP C . n A 1 432 ILE 432 497 497 ILE ILE C . n A 1 433 TYR 433 498 498 TYR TYR C . n A 1 434 GLY 434 499 499 GLY GLY C . n A 1 435 THR 435 500 500 THR THR C . n A 1 436 ASN 436 501 501 ASN ASN C . n A 1 437 ARG 437 502 502 ARG ARG C . n A 1 438 PHE 438 503 503 PHE PHE C . n A 1 439 SER 439 504 504 SER SER C . n A 1 440 GLU 440 505 505 GLU GLU C . n A 1 441 ASP 441 506 506 ASP ASP C . n A 1 442 ILE 442 507 507 ILE ILE C . n A 1 443 ARG 443 508 508 ARG ARG C . n A 1 444 ASP 444 509 509 ASP ASP C . n A 1 445 MET 445 510 510 MET MET C . n A 1 446 ILE 446 511 511 ILE ILE C . n A 1 447 GLY 447 512 512 GLY GLY C . n A 1 448 PHE 448 513 513 PHE PHE C . n A 1 449 PRO 449 514 514 PRO PRO C . n A 1 450 PRO 450 515 515 PRO PRO C . n A 1 451 GLY 451 516 516 GLY GLY C . n A 1 452 ARG 452 517 517 ARG ARG C . n A 1 453 TYR 453 518 518 TYR TYR C . n A 1 454 TRP 454 519 519 TRP TRP C . n A 1 455 GLN 455 520 520 GLN GLN C . n A 1 456 VAL 456 521 521 VAL VAL C . n A 1 457 CYS 457 522 522 CYS CYS C . n A 1 458 TRP 458 523 523 TRP TRP C . n A 1 459 ARG 459 524 524 ARG ARG C . n A 1 460 PHE 460 525 525 PHE PHE C . n A 1 461 VAL 461 526 526 VAL VAL C . n A 1 462 ALA 462 527 527 ALA ALA C . n A 1 463 PRO 463 528 528 PRO PRO C . n A 1 464 ILE 464 529 529 ILE ILE C . n A 1 465 PHE 465 530 530 PHE PHE C . n A 1 466 LEU 466 531 531 LEU LEU C . n A 1 467 LEU 467 532 532 LEU LEU C . n A 1 468 PHE 468 533 533 PHE PHE C . n A 1 469 ILE 469 534 534 ILE ILE C . n A 1 470 THR 470 535 535 THR THR C . n A 1 471 VAL 471 536 536 VAL VAL C . n A 1 472 TYR 472 537 537 TYR TYR C . n A 1 473 GLY 473 538 538 GLY GLY C . n A 1 474 LEU 474 539 539 LEU LEU C . n A 1 475 ILE 475 540 540 ILE ILE C . n A 1 476 GLY 476 541 541 GLY GLY C . n A 1 477 TYR 477 542 542 TYR TYR C . n A 1 478 GLU 478 543 543 GLU GLU C . n A 1 479 PRO 479 544 544 PRO PRO C . n A 1 480 LEU 480 545 545 LEU LEU C . n A 1 481 THR 481 546 546 THR THR C . n A 1 482 TYR 482 547 547 TYR TYR C . n A 1 483 ALA 483 548 548 ALA ALA C . n A 1 484 ASP 484 549 549 ASP ASP C . n A 1 485 TYR 485 550 550 TYR TYR C . n A 1 486 VAL 486 551 551 VAL VAL C . n A 1 487 TYR 487 552 552 TYR TYR C . n A 1 488 PRO 488 553 553 PRO PRO C . n A 1 489 SER 489 554 554 SER SER C . n A 1 490 TRP 490 555 555 TRP TRP C . n A 1 491 ALA 491 556 556 ALA ALA C . n A 1 492 ASN 492 557 557 ASN ASN C . n A 1 493 ALA 493 558 558 ALA ALA C . n A 1 494 LEU 494 559 559 LEU LEU C . n A 1 495 GLY 495 560 560 GLY GLY C . n A 1 496 TRP 496 561 561 TRP TRP C . n A 1 497 CYS 497 562 562 CYS CYS C . n A 1 498 ILE 498 563 563 ILE ILE C . n A 1 499 ALA 499 564 564 ALA ALA C . n A 1 500 GLY 500 565 565 GLY GLY C . n A 1 501 SER 501 566 566 SER SER C . n A 1 502 SER 502 567 567 SER SER C . n A 1 503 VAL 503 568 568 VAL VAL C . n A 1 504 VAL 504 569 569 VAL VAL C . n A 1 505 MET 505 570 570 MET MET C . n A 1 506 ILE 506 571 571 ILE ILE C . n A 1 507 PRO 507 572 572 PRO PRO C . n A 1 508 ALA 508 573 573 ALA ALA C . n A 1 509 VAL 509 574 574 VAL VAL C . n A 1 510 ALA 510 575 575 ALA ALA C . n A 1 511 ILE 511 576 576 ILE ILE C . n A 1 512 PHE 512 577 577 PHE PHE C . n A 1 513 LYS 513 578 578 LYS LYS C . n A 1 514 LEU 514 579 579 LEU LEU C . n A 1 515 LEU 515 580 580 LEU LEU C . n A 1 516 SER 516 581 581 SER SER C . n A 1 517 THR 517 582 582 THR THR C . n A 1 518 PRO 518 583 583 PRO PRO C . n A 1 519 GLY 519 584 584 GLY GLY C . n A 1 520 SER 520 585 585 SER SER C . n A 1 521 LEU 521 586 586 LEU LEU C . n A 1 522 ARG 522 587 587 ARG ARG C . n A 1 523 GLN 523 588 588 GLN GLN C . n A 1 524 ARG 524 589 589 ARG ARG C . n A 1 525 PHE 525 590 590 PHE PHE C . n A 1 526 THR 526 591 591 THR THR C . n A 1 527 ILE 527 592 592 ILE ILE C . n A 1 528 LEU 528 593 593 LEU LEU C . n A 1 529 THR 529 594 594 THR THR C . n A 1 530 THR 530 595 595 THR THR C . n A 1 531 PRO 531 596 596 PRO PRO C . n A 1 532 TRP 532 597 597 TRP TRP C . n A 1 533 ARG 533 598 598 ARG ARG C . n A 1 534 ASP 534 599 599 ASP ASP C . n A 1 535 GLN 535 600 600 GLN GLN C . n A 1 536 GLN 536 601 601 GLN GLN C . n A 1 537 LEU 537 602 602 LEU LEU C . n A 1 538 LEU 538 603 ? ? ? C . n A 1 539 VAL 539 604 ? ? ? C . n A 1 540 PRO 540 605 ? ? ? C . n A 1 541 ARG 541 606 ? ? ? C . n B 2 1 GLU 1 1 1 GLU GLU L . n B 2 2 ASN 2 2 2 ASN ASN L . n B 2 3 VAL 3 3 3 VAL VAL L . n B 2 4 LEU 4 4 4 LEU LEU L . n B 2 5 THR 5 5 5 THR THR L . n B 2 6 GLN 6 6 6 GLN GLN L . n B 2 7 SER 7 7 7 SER SER L . n B 2 8 PRO 8 8 8 PRO PRO L . n B 2 9 ALA 9 9 9 ALA ALA L . n B 2 10 ILE 10 10 10 ILE ILE L . n B 2 11 MET 11 11 11 MET MET L . n B 2 12 SER 12 12 12 SER SER L . n B 2 13 THR 13 13 13 THR THR L . n B 2 14 SER 14 14 14 SER SER L . n B 2 15 PRO 15 15 15 PRO PRO L . n B 2 16 GLY 16 16 16 GLY GLY L . n B 2 17 GLU 17 17 17 GLU GLU L . n B 2 18 LYS 18 18 18 LYS LYS L . n B 2 19 VAL 19 19 19 VAL VAL L . n B 2 20 THR 20 20 20 THR THR L . n B 2 21 MET 21 21 21 MET MET L . n B 2 22 THR 22 22 22 THR THR L . n B 2 23 CYS 23 23 23 CYS CYS L . n B 2 24 ARG 24 24 24 ARG ARG L . n B 2 25 ALA 25 25 25 ALA ALA L . n B 2 26 SER 26 26 26 SER SER L . n B 2 27 SER 27 27 27 SER SER L . n B 2 28 SER 28 28 28 SER SER L . n B 2 29 VAL 29 29 29 VAL VAL L . n B 2 30 GLY 30 30 30 GLY GLY L . n B 2 31 SER 31 31 31 SER SER L . n B 2 32 SER 32 32 32 SER SER L . n B 2 33 TYR 33 33 33 TYR TYR L . n B 2 34 LEU 34 34 34 LEU LEU L . n B 2 35 HIS 35 35 35 HIS HIS L . n B 2 36 TRP 36 36 36 TRP TRP L . n B 2 37 TYR 37 37 37 TYR TYR L . n B 2 38 GLN 38 38 38 GLN GLN L . n B 2 39 GLN 39 39 39 GLN GLN L . n B 2 40 LYS 40 40 40 LYS LYS L . n B 2 41 SER 41 41 41 SER SER L . n B 2 42 GLY 42 42 42 GLY GLY L . n B 2 43 ALA 43 43 43 ALA ALA L . n B 2 44 SER 44 44 44 SER SER L . n B 2 45 PRO 45 45 45 PRO PRO L . n B 2 46 LYS 46 46 46 LYS LYS L . n B 2 47 LEU 47 47 47 LEU LEU L . n B 2 48 TRP 48 48 48 TRP TRP L . n B 2 49 ILE 49 49 49 ILE ILE L . n B 2 50 TYR 50 50 50 TYR TYR L . n B 2 51 SER 51 51 51 SER SER L . n B 2 52 THR 52 52 52 THR THR L . n B 2 53 SER 53 53 53 SER SER L . n B 2 54 ASN 54 54 54 ASN ASN L . n B 2 55 LEU 55 55 55 LEU LEU L . n B 2 56 ALA 56 56 56 ALA ALA L . n B 2 57 SER 57 57 57 SER SER L . n B 2 58 GLY 58 58 58 GLY GLY L . n B 2 59 VAL 59 59 59 VAL VAL L . n B 2 60 PRO 60 60 60 PRO PRO L . n B 2 61 ALA 61 61 61 ALA ALA L . n B 2 62 ARG 62 62 62 ARG ARG L . n B 2 63 PHE 63 63 63 PHE PHE L . n B 2 64 SER 64 64 64 SER SER L . n B 2 65 GLY 65 65 65 GLY GLY L . n B 2 66 SER 66 66 66 SER SER L . n B 2 67 GLY 67 67 67 GLY GLY L . n B 2 68 SER 68 68 68 SER SER L . n B 2 69 GLY 69 69 69 GLY GLY L . n B 2 70 THR 70 70 70 THR THR L . n B 2 71 SER 71 71 71 SER SER L . n B 2 72 TYR 72 72 72 TYR TYR L . n B 2 73 SER 73 73 73 SER SER L . n B 2 74 LEU 74 74 74 LEU LEU L . n B 2 75 THR 75 75 75 THR THR L . n B 2 76 ILE 76 76 76 ILE ILE L . n B 2 77 SER 77 77 77 SER SER L . n B 2 78 SER 78 78 78 SER SER L . n B 2 79 VAL 79 79 79 VAL VAL L . n B 2 80 GLU 80 80 80 GLU GLU L . n B 2 81 ALA 81 81 81 ALA ALA L . n B 2 82 GLU 82 82 82 GLU GLU L . n B 2 83 ASP 83 83 83 ASP ASP L . n B 2 84 ALA 84 84 84 ALA ALA L . n B 2 85 ALA 85 85 85 ALA ALA L . n B 2 86 THR 86 86 86 THR THR L . n B 2 87 TYR 87 87 87 TYR TYR L . n B 2 88 TYR 88 88 88 TYR TYR L . n B 2 89 CYS 89 89 89 CYS CYS L . n B 2 90 GLN 90 90 90 GLN GLN L . n B 2 91 GLN 91 91 91 GLN GLN L . n B 2 92 PHE 92 92 92 PHE PHE L . n B 2 93 SER 93 93 93 SER SER L . n B 2 94 GLY 94 94 94 GLY GLY L . n B 2 95 TYR 95 95 95 TYR TYR L . n B 2 96 PRO 96 96 96 PRO PRO L . n B 2 97 LEU 97 97 97 LEU LEU L . n B 2 98 THR 98 98 98 THR THR L . n B 2 99 PHE 99 99 99 PHE PHE L . n B 2 100 GLY 100 100 100 GLY GLY L . n B 2 101 SER 101 101 101 SER SER L . n B 2 102 GLY 102 102 102 GLY GLY L . n B 2 103 THR 103 103 103 THR THR L . n B 2 104 LYS 104 104 104 LYS LYS L . n B 2 105 LEU 105 105 105 LEU LEU L . n B 2 106 GLU 106 106 106 GLU GLU L . n B 2 107 MET 107 107 107 MET MET L . n B 2 108 LYS 108 108 108 LYS LYS L . n B 2 109 ARG 109 109 109 ARG ARG L . n B 2 110 ALA 110 110 110 ALA ALA L . n B 2 111 ASP 111 111 111 ASP ASP L . n B 2 112 ALA 112 112 112 ALA ALA L . n B 2 113 ALA 113 113 113 ALA ALA L . n B 2 114 PRO 114 114 114 PRO PRO L . n B 2 115 THR 115 115 115 THR THR L . n B 2 116 VAL 116 116 116 VAL VAL L . n B 2 117 SER 117 117 117 SER SER L . n B 2 118 ILE 118 118 118 ILE ILE L . n B 2 119 PHE 119 119 119 PHE PHE L . n B 2 120 PRO 120 120 120 PRO PRO L . n B 2 121 PRO 121 121 121 PRO PRO L . n B 2 122 SER 122 122 122 SER SER L . n B 2 123 SER 123 123 123 SER SER L . n B 2 124 GLU 124 124 124 GLU GLU L . n B 2 125 GLN 125 125 125 GLN GLN L . n B 2 126 LEU 126 126 126 LEU LEU L . n B 2 127 THR 127 127 127 THR THR L . n B 2 128 SER 128 128 128 SER SER L . n B 2 129 GLY 129 129 129 GLY GLY L . n B 2 130 GLY 130 130 130 GLY GLY L . n B 2 131 ALA 131 131 131 ALA ALA L . n B 2 132 SER 132 132 132 SER SER L . n B 2 133 VAL 133 133 133 VAL VAL L . n B 2 134 VAL 134 134 134 VAL VAL L . n B 2 135 CYS 135 135 135 CYS CYS L . n B 2 136 PHE 136 136 136 PHE PHE L . n B 2 137 LEU 137 137 137 LEU LEU L . n B 2 138 ASN 138 138 138 ASN ASN L . n B 2 139 ASN 139 139 139 ASN ASN L . n B 2 140 PHE 140 140 140 PHE PHE L . n B 2 141 TYR 141 141 141 TYR TYR L . n B 2 142 PRO 142 142 142 PRO PRO L . n B 2 143 LYS 143 143 143 LYS LYS L . n B 2 144 ASP 144 144 144 ASP ASP L . n B 2 145 ILE 145 145 145 ILE ILE L . n B 2 146 ASN 146 146 146 ASN ASN L . n B 2 147 VAL 147 147 147 VAL VAL L . n B 2 148 LYS 148 148 148 LYS LYS L . n B 2 149 TRP 149 149 149 TRP TRP L . n B 2 150 LYS 150 150 150 LYS LYS L . n B 2 151 ILE 151 151 151 ILE ILE L . n B 2 152 GLU 152 152 152 GLU GLU L . n B 2 153 GLY 153 153 153 GLY GLY L . n B 2 154 SER 154 154 154 SER SER L . n B 2 155 GLU 155 155 155 GLU GLU L . n B 2 156 ARG 156 156 156 ARG ARG L . n B 2 157 GLN 157 157 157 GLN GLN L . n B 2 158 ASN 158 158 158 ASN ASN L . n B 2 159 GLY 159 159 159 GLY GLY L . n B 2 160 VAL 160 160 160 VAL VAL L . n B 2 161 LEU 161 161 161 LEU LEU L . n B 2 162 ASN 162 162 162 ASN ASN L . n B 2 163 SER 163 163 163 SER SER L . n B 2 164 TRP 164 164 164 TRP TRP L . n B 2 165 THR 165 165 165 THR THR L . n B 2 166 ASP 166 166 166 ASP ASP L . n B 2 167 GLN 167 167 167 GLN GLN L . n B 2 168 ASP 168 168 168 ASP ASP L . n B 2 169 SER 169 169 169 SER SER L . n B 2 170 LYS 170 170 170 LYS LYS L . n B 2 171 ASP 171 171 171 ASP ASP L . n B 2 172 SER 172 172 172 SER SER L . n B 2 173 THR 173 173 173 THR THR L . n B 2 174 TYR 174 174 174 TYR TYR L . n B 2 175 SER 175 175 175 SER SER L . n B 2 176 MET 176 176 176 MET MET L . n B 2 177 SER 177 177 177 SER SER L . n B 2 178 SER 178 178 178 SER SER L . n B 2 179 THR 179 179 179 THR THR L . n B 2 180 LEU 180 180 180 LEU LEU L . n B 2 181 THR 181 181 181 THR THR L . n B 2 182 LEU 182 182 182 LEU LEU L . n B 2 183 THR 183 183 183 THR THR L . n B 2 184 LYS 184 184 184 LYS LYS L . n B 2 185 ASP 185 185 185 ASP ASP L . n B 2 186 GLU 186 186 186 GLU GLU L . n B 2 187 TYR 187 187 187 TYR TYR L . n B 2 188 GLU 188 188 188 GLU GLU L . n B 2 189 ARG 189 189 189 ARG ARG L . n B 2 190 HIS 190 190 190 HIS HIS L . n B 2 191 ASN 191 191 191 ASN ASN L . n B 2 192 SER 192 192 192 SER SER L . n B 2 193 TYR 193 193 193 TYR TYR L . n B 2 194 THR 194 194 194 THR THR L . n B 2 195 CYS 195 195 195 CYS CYS L . n B 2 196 GLU 196 196 196 GLU GLU L . n B 2 197 ALA 197 197 197 ALA ALA L . n B 2 198 THR 198 198 198 THR THR L . n B 2 199 HIS 199 199 199 HIS HIS L . n B 2 200 LYS 200 200 200 LYS LYS L . n B 2 201 THR 201 201 201 THR THR L . n B 2 202 SER 202 202 202 SER SER L . n B 2 203 THR 203 203 203 THR THR L . n B 2 204 SER 204 204 204 SER SER L . n B 2 205 PRO 205 205 205 PRO PRO L . n B 2 206 ILE 206 206 206 ILE ILE L . n B 2 207 VAL 207 207 207 VAL VAL L . n B 2 208 LYS 208 208 208 LYS LYS L . n B 2 209 SER 209 209 209 SER SER L . n B 2 210 PHE 210 210 210 PHE PHE L . n B 2 211 ASN 211 211 211 ASN ASN L . n B 2 212 ARG 212 212 212 ARG ARG L . n B 2 213 ASN 213 213 213 ASN ASN L . n C 3 1 GLU 1 1 1 GLU GLU H . n C 3 2 VAL 2 2 2 VAL VAL H . n C 3 3 GLN 3 3 3 GLN GLN H . n C 3 4 LEU 4 4 4 LEU LEU H . n C 3 5 VAL 5 5 5 VAL VAL H . n C 3 6 GLU 6 6 6 GLU GLU H . n C 3 7 SER 7 7 7 SER SER H . n C 3 8 GLY 8 8 8 GLY GLY H . n C 3 9 GLY 9 9 9 GLY GLY H . n C 3 10 GLY 10 10 10 GLY GLY H . n C 3 11 LEU 11 11 11 LEU LEU H . n C 3 12 VAL 12 12 12 VAL VAL H . n C 3 13 LYS 13 13 13 LYS LYS H . n C 3 14 PRO 14 14 14 PRO PRO H . n C 3 15 GLY 15 15 15 GLY GLY H . n C 3 16 GLY 16 16 16 GLY GLY H . n C 3 17 SER 17 17 17 SER SER H . n C 3 18 LEU 18 18 18 LEU LEU H . n C 3 19 LYS 19 19 19 LYS LYS H . n C 3 20 LEU 20 20 20 LEU LEU H . n C 3 21 SER 21 21 21 SER SER H . n C 3 22 CYS 22 22 22 CYS CYS H . n C 3 23 ALA 23 23 23 ALA ALA H . n C 3 24 ALA 24 24 24 ALA ALA H . n C 3 25 SER 25 25 25 SER SER H . n C 3 26 GLY 26 26 26 GLY GLY H . n C 3 27 PHE 27 27 27 PHE PHE H . n C 3 28 THR 28 28 28 THR THR H . n C 3 29 PHE 29 29 29 PHE PHE H . n C 3 30 SER 30 30 30 SER SER H . n C 3 31 SER 31 31 31 SER SER H . n C 3 32 TYR 32 32 32 TYR TYR H . n C 3 33 ALA 33 33 33 ALA ALA H . n C 3 34 MET 34 34 34 MET MET H . n C 3 35 SER 35 35 35 SER SER H . n C 3 36 TRP 36 36 36 TRP TRP H . n C 3 37 VAL 37 37 37 VAL VAL H . n C 3 38 ARG 38 38 38 ARG ARG H . n C 3 39 GLN 39 39 39 GLN GLN H . n C 3 40 SER 40 40 40 SER SER H . n C 3 41 PRO 41 41 41 PRO PRO H . n C 3 42 GLU 42 42 42 GLU GLU H . n C 3 43 LYS 43 43 43 LYS LYS H . n C 3 44 ARG 44 44 44 ARG ARG H . n C 3 45 LEU 45 45 45 LEU LEU H . n C 3 46 GLU 46 46 46 GLU GLU H . n C 3 47 TRP 47 47 47 TRP TRP H . n C 3 48 VAL 48 48 48 VAL VAL H . n C 3 49 ALA 49 49 49 ALA ALA H . n C 3 50 GLU 50 50 50 GLU GLU H . n C 3 51 ILE 51 51 51 ILE ILE H . n C 3 52 SER 52 52 52 SER SER H . n C 3 53 SER 53 53 53 SER SER H . n C 3 54 GLY 54 54 54 GLY GLY H . n C 3 55 GLY 55 55 55 GLY GLY H . n C 3 56 ARG 56 56 56 ARG ARG H . n C 3 57 TYR 57 57 57 TYR TYR H . n C 3 58 ILE 58 58 58 ILE ILE H . n C 3 59 TYR 59 59 59 TYR TYR H . n C 3 60 TYR 60 60 60 TYR TYR H . n C 3 61 SER 61 61 61 SER SER H . n C 3 62 ASP 62 62 62 ASP ASP H . n C 3 63 THR 63 63 63 THR THR H . n C 3 64 VAL 64 64 64 VAL VAL H . n C 3 65 THR 65 65 65 THR THR H . n C 3 66 GLY 66 66 66 GLY GLY H . n C 3 67 ARG 67 67 67 ARG ARG H . n C 3 68 PHE 68 68 68 PHE PHE H . n C 3 69 THR 69 69 69 THR THR H . n C 3 70 ILE 70 70 70 ILE ILE H . n C 3 71 SER 71 71 71 SER SER H . n C 3 72 ARG 72 72 72 ARG ARG H . n C 3 73 ASP 73 73 73 ASP ASP H . n C 3 74 ASN 74 74 74 ASN ASN H . n C 3 75 ALA 75 75 75 ALA ALA H . n C 3 76 ARG 76 76 76 ARG ARG H . n C 3 77 ASN 77 77 77 ASN ASN H . n C 3 78 ILE 78 78 78 ILE ILE H . n C 3 79 LEU 79 79 79 LEU LEU H . n C 3 80 HIS 80 80 80 HIS HIS H . n C 3 81 LEU 81 81 81 LEU LEU H . n C 3 82 GLU 82 82 82 GLU GLU H . n C 3 83 MET 83 83 83 MET MET H . n C 3 84 SER 84 84 84 SER SER H . n C 3 85 SER 85 85 85 SER SER H . n C 3 86 LEU 86 86 86 LEU LEU H . n C 3 87 ARG 87 87 87 ARG ARG H . n C 3 88 SER 88 88 88 SER SER H . n C 3 89 GLU 89 89 89 GLU GLU H . n C 3 90 ASP 90 90 90 ASP ASP H . n C 3 91 THR 91 91 91 THR THR H . n C 3 92 ALA 92 92 92 ALA ALA H . n C 3 93 MET 93 93 93 MET MET H . n C 3 94 TYR 94 94 94 TYR TYR H . n C 3 95 TYR 95 95 95 TYR TYR H . n C 3 96 CYS 96 96 96 CYS CYS H . n C 3 97 ALA 97 97 97 ALA ALA H . n C 3 98 ARG 98 98 98 ARG ARG H . n C 3 99 GLY 99 99 99 GLY GLY H . n C 3 100 GLU 100 100 100 GLU GLU H . n C 3 101 VAL 101 101 101 VAL VAL H . n C 3 102 ARG 102 102 102 ARG ARG H . n C 3 103 GLN 103 103 103 GLN GLN H . n C 3 104 ARG 104 104 104 ARG ARG H . n C 3 105 GLY 105 105 105 GLY GLY H . n C 3 106 PHE 106 106 106 PHE PHE H . n C 3 107 ASP 107 107 107 ASP ASP H . n C 3 108 TYR 108 108 108 TYR TYR H . n C 3 109 TRP 109 109 109 TRP TRP H . n C 3 110 GLY 110 110 110 GLY GLY H . n C 3 111 GLN 111 111 111 GLN GLN H . n C 3 112 GLY 112 112 112 GLY GLY H . n C 3 113 THR 113 113 113 THR THR H . n C 3 114 THR 114 114 114 THR THR H . n C 3 115 LEU 115 115 115 LEU LEU H . n C 3 116 THR 116 116 116 THR THR H . n C 3 117 VAL 117 117 117 VAL VAL H . n C 3 118 SER 118 118 118 SER SER H . n C 3 119 SER 119 119 119 SER SER H . n C 3 120 ALA 120 120 120 ALA ALA H . n C 3 121 LYS 121 121 121 LYS LYS H . n C 3 122 THR 122 122 122 THR THR H . n C 3 123 THR 123 123 123 THR THR H . n C 3 124 ALA 124 124 124 ALA ALA H . n C 3 125 PRO 125 125 125 PRO PRO H . n C 3 126 SER 126 126 126 SER SER H . n C 3 127 VAL 127 127 127 VAL VAL H . n C 3 128 TYR 128 128 128 TYR TYR H . n C 3 129 PRO 129 129 129 PRO PRO H . n C 3 130 LEU 130 130 130 LEU LEU H . n C 3 131 ALA 131 131 131 ALA ALA H . n C 3 132 PRO 132 132 132 PRO PRO H . n C 3 133 VAL 133 133 133 VAL VAL H . n C 3 134 CYS 134 134 134 CYS CYS H . n C 3 135 GLY 135 135 135 GLY GLY H . n C 3 136 ASP 136 136 136 ASP ASP H . n C 3 137 THR 137 137 137 THR THR H . n C 3 138 THR 138 138 138 THR THR H . n C 3 139 GLY 139 139 139 GLY GLY H . n C 3 140 SER 140 140 140 SER SER H . n C 3 141 SER 141 141 141 SER SER H . n C 3 142 VAL 142 142 142 VAL VAL H . n C 3 143 THR 143 143 143 THR THR H . n C 3 144 LEU 144 144 144 LEU LEU H . n C 3 145 GLY 145 145 145 GLY GLY H . n C 3 146 CYS 146 146 146 CYS CYS H . n C 3 147 LEU 147 147 147 LEU LEU H . n C 3 148 VAL 148 148 148 VAL VAL H . n C 3 149 LYS 149 149 149 LYS LYS H . n C 3 150 GLY 150 150 150 GLY GLY H . n C 3 151 TYR 151 151 151 TYR TYR H . n C 3 152 PHE 152 152 152 PHE PHE H . n C 3 153 PRO 153 153 153 PRO PRO H . n C 3 154 GLU 154 154 154 GLU GLU H . n C 3 155 PRO 155 155 155 PRO PRO H . n C 3 156 VAL 156 156 156 VAL VAL H . n C 3 157 THR 157 157 157 THR THR H . n C 3 158 LEU 158 158 158 LEU LEU H . n C 3 159 THR 159 159 159 THR THR H . n C 3 160 TRP 160 160 160 TRP TRP H . n C 3 161 ASN 161 161 161 ASN ASN H . n C 3 162 SER 162 162 162 SER SER H . n C 3 163 GLY 163 163 163 GLY GLY H . n C 3 164 SER 164 164 164 SER SER H . n C 3 165 LEU 165 165 165 LEU LEU H . n C 3 166 SER 166 166 166 SER SER H . n C 3 167 SER 167 167 167 SER SER H . n C 3 168 GLY 168 168 168 GLY GLY H . n C 3 169 VAL 169 169 169 VAL VAL H . n C 3 170 HIS 170 170 170 HIS HIS H . n C 3 171 THR 171 171 171 THR THR H . n C 3 172 PHE 172 172 172 PHE PHE H . n C 3 173 PRO 173 173 173 PRO PRO H . n C 3 174 ALA 174 174 174 ALA ALA H . n C 3 175 VAL 175 175 175 VAL VAL H . n C 3 176 LEU 176 176 176 LEU LEU H . n C 3 177 GLN 177 177 177 GLN GLN H . n C 3 178 SER 178 178 178 SER SER H . n C 3 179 ASP 179 179 179 ASP ASP H . n C 3 180 LEU 180 180 180 LEU LEU H . n C 3 181 TYR 181 181 181 TYR TYR H . n C 3 182 THR 182 182 182 THR THR H . n C 3 183 LEU 183 183 183 LEU LEU H . n C 3 184 SER 184 184 184 SER SER H . n C 3 185 SER 185 185 185 SER SER H . n C 3 186 SER 186 186 186 SER SER H . n C 3 187 VAL 187 187 187 VAL VAL H . n C 3 188 THR 188 188 188 THR THR H . n C 3 189 VAL 189 189 189 VAL VAL H . n C 3 190 THR 190 190 190 THR THR H . n C 3 191 SER 191 191 191 SER SER H . n C 3 192 SER 192 192 192 SER SER H . n C 3 193 THR 193 193 193 THR THR H . n C 3 194 TRP 194 194 194 TRP TRP H . n C 3 195 PRO 195 195 195 PRO PRO H . n C 3 196 SER 196 196 196 SER SER H . n C 3 197 GLN 197 197 197 GLN GLN H . n C 3 198 SER 198 198 198 SER SER H . n C 3 199 ILE 199 199 199 ILE ILE H . n C 3 200 THR 200 200 200 THR THR H . n C 3 201 CYS 201 201 201 CYS CYS H . n C 3 202 ASN 202 202 202 ASN ASN H . n C 3 203 VAL 203 203 203 VAL VAL H . n C 3 204 ALA 204 204 204 ALA ALA H . n C 3 205 HIS 205 205 205 HIS HIS H . n C 3 206 PRO 206 206 206 PRO PRO H . n C 3 207 ALA 207 207 207 ALA ALA H . n C 3 208 SER 208 208 208 SER SER H . n C 3 209 SER 209 209 209 SER SER H . n C 3 210 THR 210 210 210 THR THR H . n C 3 211 LYS 211 211 211 LYS LYS H . n C 3 212 VAL 212 212 212 VAL VAL H . n C 3 213 ASP 213 213 213 ASP ASP H . n C 3 214 LYS 214 214 214 LYS LYS H . n C 3 215 LYS 215 215 215 LYS LYS H . n C 3 216 ILE 216 216 216 ILE ILE H . n C 3 217 GLU 217 217 217 GLU GLU H . n C 3 218 PRO 218 218 218 PRO PRO H . n C 3 219 ARG 219 219 219 ARG ARG H . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code D 4 Y01 1 701 601 Y01 Y01 C . E 5 NAG 1 702 602 NAG NAG C . F 6 MAL 1 703 603 MAL MAL C . G 7 MPO 1 704 604 MPO MPO C . H 8 CLR 1 705 605 CLR CLR C . I 9 1WE 1 706 606 1WE 1WE C . J 10 P4G 1 707 607 P4G P4G C . K 10 P4G 1 708 608 P4G P4G C . L 11 NA 1 709 609 NA NA C . M 11 NA 1 710 610 NA NA C . N 12 CL 1 711 611 CL CL C . O 13 HOH 1 801 701 HOH HOH C . O 13 HOH 2 802 702 HOH HOH C . O 13 HOH 3 803 703 HOH HOH C . O 13 HOH 4 804 704 HOH HOH C . O 13 HOH 5 805 705 HOH HOH C . O 13 HOH 6 806 706 HOH HOH C . O 13 HOH 7 807 707 HOH HOH C . O 13 HOH 8 808 708 HOH HOH C . O 13 HOH 9 809 709 HOH HOH C . O 13 HOH 10 810 710 HOH HOH C . O 13 HOH 11 811 711 HOH HOH C . O 13 HOH 12 812 712 HOH HOH C . O 13 HOH 13 813 713 HOH HOH C . O 13 HOH 14 814 714 HOH HOH C . O 13 HOH 15 815 715 HOH HOH C . O 13 HOH 16 816 716 HOH HOH C . P 13 HOH 1 301 301 HOH HOH L . P 13 HOH 2 302 302 HOH HOH L . P 13 HOH 3 303 303 HOH HOH L . P 13 HOH 4 304 304 HOH HOH L . P 13 HOH 5 305 305 HOH HOH L . P 13 HOH 6 306 306 HOH HOH L . P 13 HOH 7 307 307 HOH HOH L . P 13 HOH 8 308 308 HOH HOH L . P 13 HOH 9 309 309 HOH HOH L . Q 13 HOH 1 301 301 HOH HOH H . Q 13 HOH 2 302 302 HOH HOH H . Q 13 HOH 3 303 303 HOH HOH H . Q 13 HOH 4 304 304 HOH HOH H . Q 13 HOH 5 305 305 HOH HOH H . Q 13 HOH 6 306 306 HOH HOH H . Q 13 HOH 7 307 307 HOH HOH H . Q 13 HOH 8 308 308 HOH HOH H . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details trimeric _pdbx_struct_assembly.oligomeric_count 3 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 7120 ? 1 MORE -40 ? 1 'SSA (A^2)' 39170 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 O ? A GLY 18 ? C GLY 42 ? 1_555 NA ? M NA . ? C NA 710 ? 1_555 O ? A VAL 21 ? C VAL 45 ? 1_555 79.1 ? 2 O ? A GLY 18 ? C GLY 42 ? 1_555 NA ? M NA . ? C NA 710 ? 1_555 O ? A LEU 352 ? C LEU 417 ? 1_555 165.0 ? 3 O ? A VAL 21 ? C VAL 45 ? 1_555 NA ? M NA . ? C NA 710 ? 1_555 O ? A LEU 352 ? C LEU 417 ? 1_555 86.1 ? 4 O ? A GLY 18 ? C GLY 42 ? 1_555 NA ? M NA . ? C NA 710 ? 1_555 OD2 ? A ASP 355 ? C ASP 420 ? 1_555 86.9 ? 5 O ? A VAL 21 ? C VAL 45 ? 1_555 NA ? M NA . ? C NA 710 ? 1_555 OD2 ? A ASP 355 ? C ASP 420 ? 1_555 107.6 ? 6 O ? A LEU 352 ? C LEU 417 ? 1_555 NA ? M NA . ? C NA 710 ? 1_555 OD2 ? A ASP 355 ? C ASP 420 ? 1_555 95.2 ? 7 O ? A GLY 18 ? C GLY 42 ? 1_555 NA ? M NA . ? C NA 710 ? 1_555 OG ? A SER 356 ? C SER 421 ? 1_555 87.3 ? 8 O ? A VAL 21 ? C VAL 45 ? 1_555 NA ? M NA . ? C NA 710 ? 1_555 OG ? A SER 356 ? C SER 421 ? 1_555 95.8 ? 9 O ? A LEU 352 ? C LEU 417 ? 1_555 NA ? M NA . ? C NA 710 ? 1_555 OG ? A SER 356 ? C SER 421 ? 1_555 96.8 ? 10 OD2 ? A ASP 355 ? C ASP 420 ? 1_555 NA ? M NA . ? C NA 710 ? 1_555 OG ? A SER 356 ? C SER 421 ? 1_555 154.4 ? 11 O ? A ALA 20 ? C ALA 44 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 OD1 ? A ASN 25 ? C ASN 49 ? 1_555 87.7 ? 12 O ? A ALA 20 ? C ALA 44 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 O ? A SER 255 ? C SER 320 ? 1_555 74.0 ? 13 OD1 ? A ASN 25 ? C ASN 49 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 O ? A SER 255 ? C SER 320 ? 1_555 160.1 ? 14 O ? A ALA 20 ? C ALA 44 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 OG ? A SER 255 ? C SER 320 ? 1_555 147.7 ? 15 OD1 ? A ASN 25 ? C ASN 49 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 OG ? A SER 255 ? C SER 320 ? 1_555 120.4 ? 16 O ? A SER 255 ? C SER 320 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 OG ? A SER 255 ? C SER 320 ? 1_555 79.4 ? 17 O ? A ALA 20 ? C ALA 44 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 OD1 ? A ASN 287 ? C ASN 352 ? 1_555 83.3 ? 18 OD1 ? A ASN 25 ? C ASN 49 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 OD1 ? A ASN 287 ? C ASN 352 ? 1_555 88.3 ? 19 O ? A SER 255 ? C SER 320 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 OD1 ? A ASN 287 ? C ASN 352 ? 1_555 97.0 ? 20 OG ? A SER 255 ? C SER 320 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 OD1 ? A ASN 287 ? C ASN 352 ? 1_555 82.1 ? 21 O ? A ALA 20 ? C ALA 44 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 O ? O HOH . ? C HOH 805 ? 1_555 96.7 ? 22 OD1 ? A ASN 25 ? C ASN 49 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 O ? O HOH . ? C HOH 805 ? 1_555 87.0 ? 23 O ? A SER 255 ? C SER 320 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 O ? O HOH . ? C HOH 805 ? 1_555 87.6 ? 24 OG ? A SER 255 ? C SER 320 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 O ? O HOH . ? C HOH 805 ? 1_555 100.1 ? 25 OD1 ? A ASN 287 ? C ASN 352 ? 1_555 NA ? L NA . ? C NA 709 ? 1_555 O ? O HOH . ? C HOH 805 ? 1_555 175.3 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2015-05-06 2 'Structure model' 1 1 2015-05-27 3 'Structure model' 1 2 2015-06-03 4 'Structure model' 1 3 2015-11-25 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Database references' 3 4 'Structure model' Other # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? . 1 ? 'data extraction' ? ? ? ? ? ? ? ? ? ? ? PDB_EXTRACT ? ? ? 3.15 2 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS ? ? ? . 3 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? XSCALE ? ? ? . 4 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? . 5 # _pdbx_validate_close_contact.id 1 _pdbx_validate_close_contact.PDB_model_num 1 _pdbx_validate_close_contact.auth_atom_id_1 OD2 _pdbx_validate_close_contact.auth_asym_id_1 C _pdbx_validate_close_contact.auth_comp_id_1 ASP _pdbx_validate_close_contact.auth_seq_id_1 420 _pdbx_validate_close_contact.PDB_ins_code_1 ? _pdbx_validate_close_contact.label_alt_id_1 ? _pdbx_validate_close_contact.auth_atom_id_2 O _pdbx_validate_close_contact.auth_asym_id_2 C _pdbx_validate_close_contact.auth_comp_id_2 HOH _pdbx_validate_close_contact.auth_seq_id_2 801 _pdbx_validate_close_contact.PDB_ins_code_2 ? _pdbx_validate_close_contact.label_alt_id_2 ? _pdbx_validate_close_contact.dist 2.10 # _pdbx_validate_rmsd_angle.id 1 _pdbx_validate_rmsd_angle.PDB_model_num 1 _pdbx_validate_rmsd_angle.auth_atom_id_1 C _pdbx_validate_rmsd_angle.auth_asym_id_1 H _pdbx_validate_rmsd_angle.auth_comp_id_1 ALA _pdbx_validate_rmsd_angle.auth_seq_id_1 131 _pdbx_validate_rmsd_angle.PDB_ins_code_1 ? _pdbx_validate_rmsd_angle.label_alt_id_1 ? _pdbx_validate_rmsd_angle.auth_atom_id_2 N _pdbx_validate_rmsd_angle.auth_asym_id_2 H _pdbx_validate_rmsd_angle.auth_comp_id_2 PRO _pdbx_validate_rmsd_angle.auth_seq_id_2 132 _pdbx_validate_rmsd_angle.PDB_ins_code_2 ? _pdbx_validate_rmsd_angle.label_alt_id_2 ? _pdbx_validate_rmsd_angle.auth_atom_id_3 CA _pdbx_validate_rmsd_angle.auth_asym_id_3 H _pdbx_validate_rmsd_angle.auth_comp_id_3 PRO _pdbx_validate_rmsd_angle.auth_seq_id_3 132 _pdbx_validate_rmsd_angle.PDB_ins_code_3 ? _pdbx_validate_rmsd_angle.label_alt_id_3 ? _pdbx_validate_rmsd_angle.angle_value 129.45 _pdbx_validate_rmsd_angle.angle_target_value 119.30 _pdbx_validate_rmsd_angle.angle_deviation 10.15 _pdbx_validate_rmsd_angle.angle_standard_deviation 1.50 _pdbx_validate_rmsd_angle.linker_flag Y # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP C 46 ? ? -139.37 -156.09 2 1 ARG C 52 ? ? -130.51 -45.91 3 1 VAL C 391 ? ? -136.06 -66.37 4 1 ALA C 548 ? ? 41.84 -126.35 5 1 TRP L 48 ? ? -141.92 -51.43 6 1 THR L 52 ? ? 73.07 -64.66 7 1 ALA L 85 ? ? -173.41 -178.49 8 1 ALA L 131 ? ? -167.05 105.02 9 1 GLU L 152 ? ? 60.92 -131.24 10 1 LYS L 170 ? ? -85.82 -78.15 11 1 SER H 85 ? ? 25.96 64.84 12 1 THR H 138 ? ? -164.98 -168.41 13 1 LYS H 211 ? ? -159.15 72.14 14 1 PRO H 218 ? ? -84.04 48.03 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 C LYS 33 ? CG ? A LYS 9 CG 2 1 Y 1 C LYS 33 ? CD ? A LYS 9 CD 3 1 Y 1 C LYS 33 ? CE ? A LYS 9 CE 4 1 Y 1 C LYS 33 ? NZ ? A LYS 9 NZ 5 1 Y 1 C LYS 256 ? CG ? A LYS 191 CG 6 1 Y 1 C LYS 256 ? CD ? A LYS 191 CD 7 1 Y 1 C LYS 256 ? CE ? A LYS 191 CE 8 1 Y 1 C LYS 256 ? NZ ? A LYS 191 NZ 9 1 Y 1 C LYS 263 ? CG ? A LYS 198 CG 10 1 Y 1 C LYS 263 ? CD ? A LYS 198 CD 11 1 Y 1 C LYS 263 ? CE ? A LYS 198 CE 12 1 Y 1 C LYS 263 ? NZ ? A LYS 198 NZ 13 1 Y 1 C TYR 305 ? CG ? A TYR 240 CG 14 1 Y 1 C TYR 305 ? CD1 ? A TYR 240 CD1 15 1 Y 1 C TYR 305 ? CD2 ? A TYR 240 CD2 16 1 Y 1 C TYR 305 ? CE1 ? A TYR 240 CE1 17 1 Y 1 C TYR 305 ? CE2 ? A TYR 240 CE2 18 1 Y 1 C TYR 305 ? CZ ? A TYR 240 CZ 19 1 Y 1 C TYR 305 ? OH ? A TYR 240 OH 20 1 Y 1 C LYS 306 ? CG ? A LYS 241 CG 21 1 Y 1 C LYS 306 ? CD ? A LYS 241 CD 22 1 Y 1 C LYS 306 ? CE ? A LYS 241 CE 23 1 Y 1 C LYS 306 ? NZ ? A LYS 241 NZ 24 1 Y 1 C GLU 308 ? CG ? A GLU 243 CG 25 1 Y 1 C GLU 308 ? CD ? A GLU 243 CD 26 1 Y 1 C GLU 308 ? OE1 ? A GLU 243 OE1 27 1 Y 1 C GLU 308 ? OE2 ? A GLU 243 OE2 28 1 Y 1 C LYS 439 ? CG ? A LYS 374 CG 29 1 Y 1 C LYS 439 ? CD ? A LYS 374 CD 30 1 Y 1 C LYS 439 ? CE ? A LYS 374 CE 31 1 Y 1 C LYS 439 ? NZ ? A LYS 374 NZ 32 1 Y 1 C ARG 442 ? CG ? A ARG 377 CG 33 1 Y 1 C ARG 442 ? CD ? A ARG 377 CD 34 1 Y 1 C ARG 442 ? NE ? A ARG 377 NE 35 1 Y 1 C ARG 442 ? CZ ? A ARG 377 CZ 36 1 Y 1 C ARG 442 ? NH1 ? A ARG 377 NH1 37 1 Y 1 C ARG 442 ? NH2 ? A ARG 377 NH2 38 1 Y 1 C ARG 587 ? CG ? A ARG 522 CG 39 1 Y 1 C ARG 587 ? CD ? A ARG 522 CD 40 1 Y 1 C ARG 587 ? NE ? A ARG 522 NE 41 1 Y 1 C ARG 587 ? CZ ? A ARG 522 CZ 42 1 Y 1 C ARG 587 ? NH1 ? A ARG 522 NH1 43 1 Y 1 C ARG 587 ? NH2 ? A ARG 522 NH2 44 1 Y 1 C GLN 600 ? CG ? A GLN 535 CG 45 1 Y 1 C GLN 600 ? CD ? A GLN 535 CD 46 1 Y 1 C GLN 600 ? OE1 ? A GLN 535 OE1 47 1 Y 1 C GLN 600 ? NE2 ? A GLN 535 NE2 48 1 Y 1 L SER 128 ? OG ? B SER 128 OG 49 1 Y 1 L SER 169 ? OG ? B SER 169 OG 50 1 Y 1 L LYS 170 ? CG ? B LYS 170 CG 51 1 Y 1 L LYS 170 ? CD ? B LYS 170 CD 52 1 Y 1 L LYS 170 ? CE ? B LYS 170 CE 53 1 Y 1 L LYS 170 ? NZ ? B LYS 170 NZ 54 1 Y 1 L ARG 189 ? CG ? B ARG 189 CG 55 1 Y 1 L ARG 189 ? CD ? B ARG 189 CD 56 1 Y 1 L ARG 189 ? NE ? B ARG 189 NE 57 1 Y 1 L ARG 189 ? CZ ? B ARG 189 CZ 58 1 Y 1 L ARG 189 ? NH1 ? B ARG 189 NH1 59 1 Y 1 L ARG 189 ? NH2 ? B ARG 189 NH2 60 1 Y 1 H GLU 1 ? CG ? C GLU 1 CG 61 1 Y 1 H GLU 1 ? CD ? C GLU 1 CD 62 1 Y 1 H GLU 1 ? OE1 ? C GLU 1 OE1 63 1 Y 1 H GLU 1 ? OE2 ? C GLU 1 OE2 64 1 Y 1 H GLN 3 ? CG ? C GLN 3 CG 65 1 Y 1 H GLN 3 ? CD ? C GLN 3 CD 66 1 Y 1 H GLN 3 ? OE1 ? C GLN 3 OE1 67 1 Y 1 H GLN 3 ? NE2 ? C GLN 3 NE2 68 1 Y 1 H SER 30 ? OG ? C SER 30 OG 69 1 Y 1 H VAL 189 ? CG1 ? C VAL 189 CG1 70 1 Y 1 H VAL 189 ? CG2 ? C VAL 189 CG2 71 1 Y 1 H SER 198 ? OG ? C SER 198 OG 72 1 Y 1 H ARG 219 ? CG ? C ARG 219 CG 73 1 Y 1 H ARG 219 ? CD ? C ARG 219 CD 74 1 Y 1 H ARG 219 ? NE ? C ARG 219 NE 75 1 Y 1 H ARG 219 ? CZ ? C ARG 219 CZ 76 1 Y 1 H ARG 219 ? NH1 ? C ARG 219 NH1 77 1 Y 1 H ARG 219 ? NH2 ? C ARG 219 NH2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 C LEU 603 ? A LEU 538 2 1 Y 1 C VAL 604 ? A VAL 539 3 1 Y 1 C PRO 605 ? A PRO 540 4 1 Y 1 C ARG 606 ? A ARG 541 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 4 'CHOLESTEROL HEMISUCCINATE' Y01 5 N-ACETYL-D-GLUCOSAMINE NAG 6 MALTOSE MAL 7 '3[N-MORPHOLINO]PROPANE SULFONIC ACID' MPO 8 CHOLESTEROL CLR 9 '(2S)-1-phenylpropan-2-amine' 1WE 10 '1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE' P4G 11 'SODIUM ION' NA 12 'CHLORIDE ION' CL 13 water HOH #