data_4XB8 # _entry.id 4XB8 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4XB8 WWPDB D_1000205277 # loop_ _pdbx_database_related.db_name _pdbx_database_related.details _pdbx_database_related.db_id _pdbx_database_related.content_type PDB . 4WVR unspecified PDB . 4X5L unspecified PDB . 4X83 unspecified PDB . 4X8X unspecified PDB . 4X9F unspecified PDB . 4X9G unspecified PDB . 4X9H unspecified PDB . 4X9I unspecified PDB . 4X9B unspecified PDB . 4XB7 unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 4XB8 _pdbx_database_status.recvd_initial_deposition_date 2014-12-16 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBJ _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Chen, Q.' 1 'Yu, Y.' 2 'Li, S.A.' 3 'cheng, L.' 4 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country US _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'Sci Adv' _citation.journal_id_ASTM ? _citation.journal_id_CSD ? _citation.journal_id_ISSN 2375-2548 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 2 _citation.language ? _citation.page_first e1501118 _citation.page_last e1501118 _citation.title 'Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition' _citation.year 2016 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1126/sciadv.1501118 _citation.pdbx_database_id_PubMed 27386517 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Li, S.A.' 1 primary 'Cheng, L.' 2 primary 'Yu, Y.' 3 primary 'Chen, Q.' 4 # _cell.entry_id 4XB8 _cell.length_a 66.672 _cell.length_b 57.269 _cell.length_c 129.946 _cell.angle_alpha 90.00 _cell.angle_beta 93.65 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? # _symmetry.entry_id 4XB8 _symmetry.space_group_name_H-M 'P 1 21 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 4 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Down Syndrome Cell Adhesion Molecule, isoform 9.44' 43414.879 2 ? ? 'N-terminal four Ig domains' ? 2 non-polymer syn N-ACETYL-D-GLUCOSAMINE 221.208 7 ? ? ? ? 3 non-polymer man BETA-D-MANNOSE 180.156 1 ? ? ? ? 4 non-polymer man ALPHA-D-MANNOSE 180.156 1 ? ? ? ? 5 non-polymer syn 'ZINC ION' 65.409 6 ? ? ? ? 6 water nat water 18.015 12 ? ? ? ? # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;GGADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVH AQVYACLARNQFGSIISRDVHVRAVVIQSYESEADNEYVIRGNSVVMKCEIPSYVADFVFVDLWLDSEGRNYYPNNAAET DGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVGSKAPTFATASKISSLLGSSSSDIVLL CQAQAFPVPYTRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKID PPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGG ; _entity_poly.pdbx_seq_one_letter_code_can ;GGADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVH AQVYACLARNQFGSIISRDVHVRAVVIQSYESEADNEYVIRGNSVVMKCEIPSYVADFVFVDLWLDSEGRNYYPNNAAET DGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVGSKAPTFATASKISSLLGSSSSDIVLL CQAQAFPVPYTRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKID PPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGG ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLY n 1 2 GLY n 1 3 ALA n 1 4 ASP n 1 5 GLN n 1 6 LYS n 1 7 GLY n 1 8 PRO n 1 9 VAL n 1 10 PHE n 1 11 LEU n 1 12 LYS n 1 13 GLU n 1 14 PRO n 1 15 THR n 1 16 ASN n 1 17 ARG n 1 18 ILE n 1 19 ASP n 1 20 PHE n 1 21 SER n 1 22 ASN n 1 23 SER n 1 24 THR n 1 25 GLY n 1 26 ALA n 1 27 GLU n 1 28 ILE n 1 29 GLU n 1 30 CYS n 1 31 LYS n 1 32 ALA n 1 33 SER n 1 34 GLY n 1 35 ASN n 1 36 PRO n 1 37 MET n 1 38 PRO n 1 39 GLU n 1 40 ILE n 1 41 ILE n 1 42 TRP n 1 43 ILE n 1 44 ARG n 1 45 SER n 1 46 ASP n 1 47 GLY n 1 48 THR n 1 49 ALA n 1 50 VAL n 1 51 GLY n 1 52 ASP n 1 53 VAL n 1 54 PRO n 1 55 GLY n 1 56 LEU n 1 57 ARG n 1 58 GLN n 1 59 ILE n 1 60 SER n 1 61 SER n 1 62 ASP n 1 63 GLY n 1 64 LYS n 1 65 LEU n 1 66 VAL n 1 67 PHE n 1 68 PRO n 1 69 PRO n 1 70 PHE n 1 71 ARG n 1 72 ALA n 1 73 GLU n 1 74 ASP n 1 75 TYR n 1 76 ARG n 1 77 GLN n 1 78 GLU n 1 79 VAL n 1 80 HIS n 1 81 ALA n 1 82 GLN n 1 83 VAL n 1 84 TYR n 1 85 ALA n 1 86 CYS n 1 87 LEU n 1 88 ALA n 1 89 ARG n 1 90 ASN n 1 91 GLN n 1 92 PHE n 1 93 GLY n 1 94 SER n 1 95 ILE n 1 96 ILE n 1 97 SER n 1 98 ARG n 1 99 ASP n 1 100 VAL n 1 101 HIS n 1 102 VAL n 1 103 ARG n 1 104 ALA n 1 105 VAL n 1 106 VAL n 1 107 ILE n 1 108 GLN n 1 109 SER n 1 110 TYR n 1 111 GLU n 1 112 SER n 1 113 GLU n 1 114 ALA n 1 115 ASP n 1 116 ASN n 1 117 GLU n 1 118 TYR n 1 119 VAL n 1 120 ILE n 1 121 ARG n 1 122 GLY n 1 123 ASN n 1 124 SER n 1 125 VAL n 1 126 VAL n 1 127 MET n 1 128 LYS n 1 129 CYS n 1 130 GLU n 1 131 ILE n 1 132 PRO n 1 133 SER n 1 134 TYR n 1 135 VAL n 1 136 ALA n 1 137 ASP n 1 138 PHE n 1 139 VAL n 1 140 PHE n 1 141 VAL n 1 142 ASP n 1 143 LEU n 1 144 TRP n 1 145 LEU n 1 146 ASP n 1 147 SER n 1 148 GLU n 1 149 GLY n 1 150 ARG n 1 151 ASN n 1 152 TYR n 1 153 TYR n 1 154 PRO n 1 155 ASN n 1 156 ASN n 1 157 ALA n 1 158 ALA n 1 159 GLU n 1 160 THR n 1 161 ASP n 1 162 GLY n 1 163 LYS n 1 164 TYR n 1 165 LEU n 1 166 VAL n 1 167 LEU n 1 168 PRO n 1 169 SER n 1 170 GLY n 1 171 GLU n 1 172 LEU n 1 173 HIS n 1 174 ILE n 1 175 ARG n 1 176 GLU n 1 177 VAL n 1 178 GLY n 1 179 PRO n 1 180 GLU n 1 181 ASP n 1 182 GLY n 1 183 TYR n 1 184 LYS n 1 185 SER n 1 186 TYR n 1 187 GLN n 1 188 CYS n 1 189 ARG n 1 190 THR n 1 191 LYS n 1 192 HIS n 1 193 ARG n 1 194 LEU n 1 195 THR n 1 196 GLY n 1 197 GLU n 1 198 THR n 1 199 ARG n 1 200 LEU n 1 201 SER n 1 202 ALA n 1 203 THR n 1 204 LYS n 1 205 GLY n 1 206 ARG n 1 207 LEU n 1 208 VAL n 1 209 ILE n 1 210 THR n 1 211 GLU n 1 212 PRO n 1 213 VAL n 1 214 GLY n 1 215 SER n 1 216 LYS n 1 217 ALA n 1 218 PRO n 1 219 THR n 1 220 PHE n 1 221 ALA n 1 222 THR n 1 223 ALA n 1 224 SER n 1 225 LYS n 1 226 ILE n 1 227 SER n 1 228 SER n 1 229 LEU n 1 230 LEU n 1 231 GLY n 1 232 SER n 1 233 SER n 1 234 SER n 1 235 SER n 1 236 ASP n 1 237 ILE n 1 238 VAL n 1 239 LEU n 1 240 LEU n 1 241 CYS n 1 242 GLN n 1 243 ALA n 1 244 GLN n 1 245 ALA n 1 246 PHE n 1 247 PRO n 1 248 VAL n 1 249 PRO n 1 250 TYR n 1 251 THR n 1 252 ARG n 1 253 TRP n 1 254 TYR n 1 255 LYS n 1 256 PHE n 1 257 ILE n 1 258 GLU n 1 259 GLY n 1 260 THR n 1 261 THR n 1 262 ARG n 1 263 LYS n 1 264 GLN n 1 265 ALA n 1 266 VAL n 1 267 VAL n 1 268 LEU n 1 269 ASN n 1 270 ASP n 1 271 ARG n 1 272 VAL n 1 273 LYS n 1 274 GLN n 1 275 VAL n 1 276 SER n 1 277 GLY n 1 278 THR n 1 279 LEU n 1 280 ILE n 1 281 ILE n 1 282 LYS n 1 283 ASP n 1 284 ALA n 1 285 VAL n 1 286 VAL n 1 287 GLU n 1 288 ASP n 1 289 SER n 1 290 GLY n 1 291 LYS n 1 292 TYR n 1 293 LEU n 1 294 CYS n 1 295 VAL n 1 296 VAL n 1 297 ASN n 1 298 ASN n 1 299 SER n 1 300 VAL n 1 301 GLY n 1 302 GLY n 1 303 GLU n 1 304 SER n 1 305 VAL n 1 306 GLU n 1 307 THR n 1 308 VAL n 1 309 LEU n 1 310 THR n 1 311 VAL n 1 312 THR n 1 313 ALA n 1 314 PRO n 1 315 LEU n 1 316 SER n 1 317 ALA n 1 318 LYS n 1 319 ILE n 1 320 ASP n 1 321 PRO n 1 322 PRO n 1 323 THR n 1 324 GLN n 1 325 THR n 1 326 VAL n 1 327 ASP n 1 328 PHE n 1 329 GLY n 1 330 ARG n 1 331 PRO n 1 332 ALA n 1 333 VAL n 1 334 PHE n 1 335 THR n 1 336 CYS n 1 337 GLN n 1 338 TYR n 1 339 THR n 1 340 GLY n 1 341 ASN n 1 342 PRO n 1 343 ILE n 1 344 LYS n 1 345 THR n 1 346 VAL n 1 347 SER n 1 348 TRP n 1 349 MET n 1 350 LYS n 1 351 ASP n 1 352 GLY n 1 353 LYS n 1 354 ALA n 1 355 ILE n 1 356 GLY n 1 357 HIS n 1 358 SER n 1 359 GLU n 1 360 PRO n 1 361 VAL n 1 362 LEU n 1 363 ARG n 1 364 ILE n 1 365 GLU n 1 366 SER n 1 367 VAL n 1 368 LYS n 1 369 LYS n 1 370 GLU n 1 371 ASP n 1 372 LYS n 1 373 GLY n 1 374 MET n 1 375 TYR n 1 376 GLN n 1 377 CYS n 1 378 PHE n 1 379 VAL n 1 380 ARG n 1 381 ASN n 1 382 ASP n 1 383 GLN n 1 384 GLU n 1 385 SER n 1 386 ALA n 1 387 GLU n 1 388 ALA n 1 389 SER n 1 390 ALA n 1 391 GLU n 1 392 LEU n 1 393 LYS n 1 394 LEU n 1 395 GLY n 1 396 GLY n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type 'Biological sequence' _entity_src_gen.pdbx_beg_seq_num 1 _entity_src_gen.pdbx_end_seq_num 396 _entity_src_gen.gene_src_common_name ? _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene ? _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 7227 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Trichoplusia ni' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7111 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type baculovirus _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.db_code 4XB8 _struct_ref.db_name PDB _struct_ref.details ? _struct_ref.entity_id 1 _struct_ref.id 1 _struct_ref.seq_align ? _struct_ref.seq_dif ? _struct_ref.pdbx_db_accession 4XB8 _struct_ref.pdbx_db_isoform ? _struct_ref.pdbx_seq_one_letter_code ? _struct_ref.pdbx_align_begin 1 _struct_ref.pdbx_align_end ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4XB8 A 1 ? 396 ? 4XB8 -3 ? 392 ? -3 392 2 1 4XB8 B 1 ? 396 ? 4XB8 -3 ? 392 ? -3 392 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 4XB8 _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 2.85 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 56.86 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 289 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '0.1M Sodium Cacodylate pH 6.4, 0.2M Zinc Acetate, 20% (w/v) PEG 4000' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type MARRESEARCH _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2014-06-10 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.979 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'BSRF BEAMLINE 3W1A' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 0.979 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline 3W1A _diffrn_source.pdbx_synchrotron_site BSRF # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 4XB8 _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 3.2 _reflns.d_resolution_low 50 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 16383 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 99.6 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 4.9 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 8.1 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 4XB8 _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 16381 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.36 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 47.988 _refine.ls_d_res_high 3.202 _refine.ls_percent_reflns_obs 99.67 _refine.ls_R_factor_obs 0.2561 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.2530 _refine.ls_R_factor_R_free 0.3160 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.09 _refine.ls_number_reflns_R_free 834 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean ? _refine.aniso_B[1][1] ? _refine.aniso_B[2][2] ? _refine.aniso_B[3][3] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][3] ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_ls_cross_valid_method 'FREE R-VALUE' _refine.details ? _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.56 _refine.pdbx_overall_phase_error 35.06 _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6024 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 126 _refine_hist.number_atoms_solvent 12 _refine_hist.number_atoms_total 6162 _refine_hist.d_res_high 3.202 _refine_hist.d_res_low 47.988 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function f_bond_d 0.004 ? ? 6310 'X-RAY DIFFRACTION' ? f_angle_d 0.912 ? ? 8525 'X-RAY DIFFRACTION' ? f_dihedral_angle_d 14.533 ? ? 2335 'X-RAY DIFFRACTION' ? f_chiral_restr 0.036 ? ? 982 'X-RAY DIFFRACTION' ? f_plane_restr 0.004 ? ? 1097 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_all _refine_ls_shell.R_factor_all 'X-RAY DIFFRACTION' . 3.2024 3.4030 2513 0.3462 98.00 0.4615 . . 139 . . 'X-RAY DIFFRACTION' . 3.4030 3.6657 2582 0.2955 100.00 0.3807 . . 135 . . 'X-RAY DIFFRACTION' . 3.6657 4.0344 2575 0.2608 100.00 0.3385 . . 142 . . 'X-RAY DIFFRACTION' . 4.0344 4.6178 2584 0.2342 100.00 0.3191 . . 136 . . 'X-RAY DIFFRACTION' . 4.6178 5.8163 2616 0.2265 100.00 0.2600 . . 133 . . 'X-RAY DIFFRACTION' . 5.8163 47.9938 2677 0.2370 100.00 0.2740 . . 149 . . # _struct.entry_id 4XB8 _struct.title 'Crystal structure of Dscam1 isoform 9.44, N-terminal four Ig domains (with zinc)' _struct.pdbx_descriptor 'Down Syndrome Cell Adhesion Molecule, isoform 9.44' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 4XB8 _struct_keywords.text 'Ig fold, cell adhesion' _struct_keywords.pdbx_keywords 'CELL ADHESION' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 2 ? E N N 3 ? F N N 4 ? G N N 2 ? H N N 2 ? I N N 5 ? J N N 5 ? K N N 5 ? L N N 5 ? M N N 2 ? N N N 2 ? O N N 2 ? P N N 5 ? Q N N 5 ? R N N 6 ? S N N 6 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 ARG A 71 ? TYR A 75 ? ARG A 67 TYR A 71 5 ? 5 HELX_P HELX_P2 AA2 ARG A 76 ? ALA A 81 ? ARG A 72 ALA A 77 1 ? 6 HELX_P HELX_P3 AA3 GLY A 178 ? GLY A 182 ? GLY A 174 GLY A 178 5 ? 5 HELX_P HELX_P4 AA4 VAL A 285 ? SER A 289 ? VAL A 281 SER A 285 5 ? 5 HELX_P HELX_P5 AA5 ARG B 76 ? ALA B 81 ? ARG B 72 ALA B 77 1 ? 6 HELX_P HELX_P6 AA6 TYR B 134 ? PHE B 138 ? TYR B 130 PHE B 134 5 ? 5 HELX_P HELX_P7 AA7 GLY B 178 ? TYR B 183 ? GLY B 174 TYR B 179 1 ? 6 HELX_P HELX_P8 AA8 VAL B 285 ? SER B 289 ? VAL B 281 SER B 285 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 30 SG ? ? ? 1_555 A CYS 86 SG ? ? A CYS 26 A CYS 82 1_555 ? ? ? ? ? ? ? 2.033 ? disulf2 disulf ? ? A CYS 129 SG ? ? ? 1_555 A CYS 188 SG ? ? A CYS 125 A CYS 184 1_555 ? ? ? ? ? ? ? 2.034 ? disulf3 disulf ? ? A CYS 241 SG ? ? ? 1_555 A CYS 294 SG ? ? A CYS 237 A CYS 290 1_555 ? ? ? ? ? ? ? 2.032 ? disulf4 disulf ? ? A CYS 336 SG ? ? ? 1_555 A CYS 377 SG ? ? A CYS 332 A CYS 373 1_555 ? ? ? ? ? ? ? 2.033 ? disulf5 disulf ? ? B CYS 30 SG ? ? ? 1_555 B CYS 86 SG ? ? B CYS 26 B CYS 82 1_555 ? ? ? ? ? ? ? 2.034 ? disulf6 disulf ? ? B CYS 129 SG ? ? ? 1_555 B CYS 188 SG ? ? B CYS 125 B CYS 184 1_555 ? ? ? ? ? ? ? 2.029 ? disulf7 disulf ? ? B CYS 241 SG ? ? ? 1_555 B CYS 294 SG ? ? B CYS 237 B CYS 290 1_555 ? ? ? ? ? ? ? 2.032 ? disulf8 disulf ? ? B CYS 336 SG ? ? ? 1_555 B CYS 377 SG ? ? B CYS 332 B CYS 373 1_555 ? ? ? ? ? ? ? 2.033 ? metalc1 metalc ? ? A GLU 13 OE1 ? ? ? 1_555 J ZN . ZN ? ? A GLU 9 A ZN 408 1_555 ? ? ? ? ? ? ? 2.038 ? metalc2 metalc ? ? A GLU 13 OE2 ? ? ? 1_555 J ZN . ZN ? ? A GLU 9 A ZN 408 1_555 ? ? ? ? ? ? ? 2.034 ? covale1 covale one ? A ASN 22 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 18 A NAG 401 1_555 ? ? ? ? ? ? ? 1.439 ? metalc3 metalc ? ? A ASP 99 OD1 ? ? ? 1_555 I ZN . ZN ? ? A ASP 95 A ZN 407 1_555 ? ? ? ? ? ? ? 1.974 ? metalc4 metalc ? ? A ASP 99 OD2 ? ? ? 1_555 I ZN . ZN ? ? A ASP 95 A ZN 407 1_555 ? ? ? ? ? ? ? 2.021 ? metalc5 metalc ? ? A HIS 101 NE2 ? ? ? 1_555 I ZN . ZN ? ? A HIS 97 A ZN 407 1_555 ? ? ? ? ? ? ? 2.046 ? metalc6 metalc ? ? A GLU 113 OE1 ? ? ? 1_555 K ZN . ZN ? ? A GLU 109 A ZN 409 1_555 ? ? ? ? ? ? ? 2.007 ? metalc7 metalc ? ? A GLU 113 OE2 ? ? ? 1_555 K ZN . ZN ? ? A GLU 109 A ZN 409 1_555 ? ? ? ? ? ? ? 1.992 ? metalc8 metalc ? ? A ASP 115 OD1 ? ? ? 1_555 L ZN . ZN ? ? A ASP 111 A ZN 410 1_555 ? ? ? ? ? ? ? 1.983 ? metalc9 metalc ? ? A ASP 115 OD2 ? ? ? 1_555 L ZN . ZN ? ? A ASP 111 A ZN 410 1_555 ? ? ? ? ? ? ? 1.998 ? metalc10 metalc ? ? A GLU 130 OE1 ? ? ? 1_555 K ZN . ZN ? ? A GLU 126 A ZN 409 1_555 ? ? ? ? ? ? ? 1.985 ? metalc11 metalc ? ? A GLU 130 OE2 ? ? ? 1_555 K ZN . ZN ? ? A GLU 126 A ZN 409 1_555 ? ? ? ? ? ? ? 1.999 ? covale2 covale one ? A ASN 297 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 293 A NAG 405 1_555 ? ? ? ? ? ? ? 1.446 ? metalc12 metalc ? ? A GLU 387 O ? ? ? 1_555 J ZN . ZN ? ? A GLU 383 A ZN 408 1_555 ? ? ? ? ? ? ? 2.080 ? metalc13 metalc ? ? A GLU 387 OE1 ? ? ? 1_555 J ZN . ZN ? ? A GLU 383 A ZN 408 1_555 ? ? ? ? ? ? ? 1.977 ? metalc14 metalc ? ? B GLU 13 OE1 ? ? ? 1_555 Q ZN . ZN ? ? B GLU 9 B ZN 405 1_555 ? ? ? ? ? ? ? 1.984 ? metalc15 metalc ? ? B GLU 13 OE2 ? ? ? 1_555 Q ZN . ZN ? ? B GLU 9 B ZN 405 1_555 ? ? ? ? ? ? ? 1.995 ? covale3 covale one ? B ASN 22 ND2 ? ? ? 1_555 M NAG . C1 ? ? B ASN 18 B NAG 401 1_555 ? ? ? ? ? ? ? 1.441 ? metalc16 metalc ? ? B ASP 99 OD1 ? ? ? 1_555 P ZN . ZN ? ? B ASP 95 B ZN 404 1_555 ? ? ? ? ? ? ? 1.990 ? metalc17 metalc ? ? B ASP 99 OD2 ? ? ? 1_555 P ZN . ZN ? ? B ASP 95 B ZN 404 1_555 ? ? ? ? ? ? ? 1.995 ? metalc18 metalc ? ? B HIS 101 NE2 ? ? ? 1_555 P ZN . ZN ? ? B HIS 97 B ZN 404 1_555 ? ? ? ? ? ? ? 2.024 ? metalc19 metalc ? ? B GLU 113 OE1 ? ? ? 1_555 L ZN . ZN ? ? B GLU 109 A ZN 410 1_555 ? ? ? ? ? ? ? 1.997 ? metalc20 metalc ? ? B GLU 113 OE2 ? ? ? 1_555 L ZN . ZN ? ? B GLU 109 A ZN 410 1_555 ? ? ? ? ? ? ? 2.003 ? metalc21 metalc ? ? B ASP 115 OD1 ? ? ? 1_555 K ZN . ZN ? ? B ASP 111 A ZN 409 1_555 ? ? ? ? ? ? ? 1.980 ? metalc22 metalc ? ? B ASP 115 OD2 ? ? ? 1_555 K ZN . ZN ? ? B ASP 111 A ZN 409 1_555 ? ? ? ? ? ? ? 1.999 ? metalc23 metalc ? ? B GLU 130 OE1 ? ? ? 1_555 L ZN . ZN ? ? B GLU 126 A ZN 410 1_555 ? ? ? ? ? ? ? 1.989 ? metalc24 metalc ? ? B GLU 130 OE2 ? ? ? 1_555 L ZN . ZN ? ? B GLU 126 A ZN 410 1_555 ? ? ? ? ? ? ? 1.992 ? covale4 covale one ? B ASN 297 ND2 ? ? ? 1_555 N NAG . C1 ? ? B ASN 293 B NAG 402 1_555 ? ? ? ? ? ? ? 1.436 ? metalc25 metalc ? ? B GLU 387 O ? ? ? 1_555 Q ZN . ZN ? ? B GLU 383 B ZN 405 1_555 ? ? ? ? ? ? ? 2.000 ? metalc26 metalc ? ? B GLU 387 OE1 ? ? ? 1_555 Q ZN . ZN ? ? B GLU 383 B ZN 405 1_555 ? ? ? ? ? ? ? 1.998 ? covale5 covale both ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? A NAG 401 A NAG 402 1_555 ? ? ? ? ? ? ? 1.431 ? covale6 covale both ? D NAG . O4 ? ? ? 1_555 E BMA . C1 ? ? A NAG 402 A BMA 403 1_555 ? ? ? ? ? ? ? 1.441 ? covale7 covale one ? E BMA . O6 ? ? ? 1_555 F MAN . C1 ? ? A BMA 403 A MAN 404 1_555 ? ? ? ? ? ? ? 1.452 ? covale8 covale both ? G NAG . O4 ? ? ? 1_555 H NAG . C1 ? ? A NAG 405 A NAG 406 1_555 ? ? ? ? ? ? ? 1.451 ? metalc27 metalc ? ? I ZN . ZN ? ? ? 1_555 R HOH . O ? ? A ZN 407 A HOH 505 1_555 ? ? ? ? ? ? ? 2.084 ? covale9 covale both ? N NAG . O4 ? ? ? 1_555 O NAG . C1 ? ? B NAG 402 B NAG 403 1_555 ? ? ? ? ? ? ? 1.444 ? metalc28 metalc ? ? P ZN . ZN ? ? ? 1_555 S HOH . O ? ? B ZN 404 B HOH 505 1_555 ? ? ? ? ? ? ? 2.090 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ASN 35 A . ? ASN 31 A PRO 36 A ? PRO 32 A 1 -1.08 2 PHE 246 A . ? PHE 242 A PRO 247 A ? PRO 243 A 1 -5.74 3 ASP 320 A . ? ASP 316 A PRO 321 A ? PRO 317 A 1 -6.61 4 ASN 341 A . ? ASN 337 A PRO 342 A ? PRO 338 A 1 -8.12 5 ASN 35 B . ? ASN 31 B PRO 36 B ? PRO 32 B 1 -6.07 6 PHE 246 B . ? PHE 242 B PRO 247 B ? PRO 243 B 1 13.65 7 ASP 320 B . ? ASP 316 B PRO 321 B ? PRO 317 B 1 -4.86 8 ASN 341 B . ? ASN 337 B PRO 342 B ? PRO 338 B 1 -10.68 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 2 ? AA2 ? 4 ? AA3 ? 4 ? AA4 ? 3 ? AA5 ? 2 ? AA6 ? 5 ? AA7 ? 4 ? AA8 ? 3 ? AA9 ? 5 ? AB1 ? 4 ? AB2 ? 3 ? AB3 ? 5 ? AB4 ? 3 ? AB5 ? 3 ? AB6 ? 2 ? AB7 ? 2 ? AB8 ? 3 ? AB9 ? 3 ? AC1 ? 2 ? AC2 ? 5 ? AC3 ? 3 ? AC4 ? 3 ? AC5 ? 5 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA2 1 2 ? parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA3 1 2 ? parallel AA3 2 3 ? anti-parallel AA3 3 4 ? anti-parallel AA4 1 2 ? anti-parallel AA4 2 3 ? anti-parallel AA5 1 2 ? anti-parallel AA6 1 2 ? parallel AA6 2 3 ? anti-parallel AA6 3 4 ? anti-parallel AA6 4 5 ? anti-parallel AA7 1 2 ? parallel AA7 2 3 ? anti-parallel AA7 3 4 ? anti-parallel AA8 1 2 ? anti-parallel AA8 2 3 ? anti-parallel AA9 1 2 ? parallel AA9 2 3 ? anti-parallel AA9 3 4 ? anti-parallel AA9 4 5 ? anti-parallel AB1 1 2 ? parallel AB1 2 3 ? anti-parallel AB1 3 4 ? anti-parallel AB2 1 2 ? anti-parallel AB2 2 3 ? anti-parallel AB3 1 2 ? parallel AB3 2 3 ? anti-parallel AB3 3 4 ? anti-parallel AB3 4 5 ? anti-parallel AB4 1 2 ? anti-parallel AB4 2 3 ? anti-parallel AB5 1 2 ? anti-parallel AB5 2 3 ? anti-parallel AB6 1 2 ? anti-parallel AB7 1 2 ? parallel AB8 1 2 ? anti-parallel AB8 2 3 ? anti-parallel AB9 1 2 ? anti-parallel AB9 2 3 ? anti-parallel AC1 1 2 ? anti-parallel AC2 1 2 ? parallel AC2 2 3 ? anti-parallel AC2 3 4 ? anti-parallel AC2 4 5 ? anti-parallel AC3 1 2 ? anti-parallel AC3 2 3 ? anti-parallel AC4 1 2 ? anti-parallel AC4 2 3 ? anti-parallel AC5 1 2 ? parallel AC5 2 3 ? anti-parallel AC5 3 4 ? anti-parallel AC5 4 5 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 VAL A 9 ? PHE A 10 ? VAL A 5 PHE A 6 AA1 2 ALA A 32 ? SER A 33 ? ALA A 28 SER A 29 AA2 1 ARG A 17 ? SER A 21 ? ARG A 13 SER A 17 AA2 2 VAL A 100 ? VAL A 105 ? VAL A 96 VAL A 101 AA2 3 GLN A 82 ? ARG A 89 ? GLN A 78 ARG A 85 AA2 4 GLU A 39 ? ARG A 44 ? GLU A 35 ARG A 40 AA3 1 ARG A 17 ? SER A 21 ? ARG A 13 SER A 17 AA3 2 VAL A 100 ? VAL A 105 ? VAL A 96 VAL A 101 AA3 3 GLN A 82 ? ARG A 89 ? GLN A 78 ARG A 85 AA3 4 SER A 94 ? ILE A 96 ? SER A 90 ILE A 92 AA4 1 ALA A 26 ? GLU A 29 ? ALA A 22 GLU A 25 AA4 2 LYS A 64 ? PHE A 67 ? LYS A 60 PHE A 63 AA4 3 GLN A 58 ? ILE A 59 ? GLN A 54 ILE A 55 AA5 1 GLU A 113 ? ALA A 114 ? GLU A 109 ALA A 110 AA5 2 CYS A 129 ? GLU A 130 ? CYS A 125 GLU A 126 AA6 1 GLU A 117 ? ILE A 120 ? GLU A 113 ILE A 116 AA6 2 GLY A 205 ? THR A 210 ? GLY A 201 THR A 206 AA6 3 SER A 185 ? HIS A 192 ? SER A 181 HIS A 188 AA6 4 VAL A 139 ? ASP A 146 ? VAL A 135 ASP A 142 AA6 5 ASN A 151 ? TYR A 152 ? ASN A 147 TYR A 148 AA7 1 GLU A 117 ? ILE A 120 ? GLU A 113 ILE A 116 AA7 2 GLY A 205 ? THR A 210 ? GLY A 201 THR A 206 AA7 3 SER A 185 ? HIS A 192 ? SER A 181 HIS A 188 AA7 4 THR A 198 ? LEU A 200 ? THR A 194 LEU A 196 AA8 1 VAL A 125 ? MET A 127 ? VAL A 121 MET A 123 AA8 2 LEU A 172 ? ILE A 174 ? LEU A 168 ILE A 170 AA8 3 TYR A 164 ? VAL A 166 ? TYR A 160 VAL A 162 AA9 1 ILE A 226 ? SER A 232 ? ILE A 222 SER A 228 AA9 2 GLY A 301 ? ASP A 320 ? GLY A 297 ASP A 316 AA9 3 GLY A 290 ? ASN A 298 ? GLY A 286 ASN A 294 AA9 4 TYR A 250 ? PHE A 256 ? TYR A 246 PHE A 252 AA9 5 LYS A 263 ? ALA A 265 ? LYS A 259 ALA A 261 AB1 1 ILE A 226 ? SER A 232 ? ILE A 222 SER A 228 AB1 2 GLY A 301 ? ASP A 320 ? GLY A 297 ASP A 316 AB1 3 ALA A 332 ? ASN A 341 ? ALA A 328 ASN A 337 AB1 4 VAL A 361 ? ILE A 364 ? VAL A 357 ILE A 360 AB2 1 VAL A 238 ? LEU A 239 ? VAL A 234 LEU A 235 AB2 2 THR A 278 ? ILE A 280 ? THR A 274 ILE A 276 AB2 3 LYS A 273 ? VAL A 275 ? LYS A 269 VAL A 271 AB3 1 THR A 323 ? ASP A 327 ? THR A 319 ASP A 323 AB3 2 GLU A 384 ? GLY A 395 ? GLU A 380 GLY A 391 AB3 3 MET A 374 ? ASN A 381 ? MET A 370 ASN A 377 AB3 4 THR A 345 ? LYS A 350 ? THR A 341 LYS A 346 AB3 5 LYS A 353 ? ILE A 355 ? LYS A 349 ILE A 351 AB4 1 ALA B 26 ? ILE B 28 ? ALA B 22 ILE B 24 AB4 2 LYS B 64 ? PHE B 67 ? LYS B 60 PHE B 63 AB4 3 GLN B 58 ? SER B 60 ? GLN B 54 SER B 56 AB5 1 ILE B 41 ? ARG B 44 ? ILE B 37 ARG B 40 AB5 2 TYR B 84 ? ASN B 90 ? TYR B 80 ASN B 86 AB5 3 GLY B 93 ? ILE B 96 ? GLY B 89 ILE B 92 AB6 1 GLU B 113 ? ALA B 114 ? GLU B 109 ALA B 110 AB6 2 CYS B 129 ? GLU B 130 ? CYS B 125 GLU B 126 AB7 1 GLU B 117 ? ILE B 120 ? GLU B 113 ILE B 116 AB7 2 LEU B 207 ? THR B 210 ? LEU B 203 THR B 206 AB8 1 VAL B 125 ? MET B 127 ? VAL B 121 MET B 123 AB8 2 LEU B 172 ? ILE B 174 ? LEU B 168 ILE B 170 AB8 3 LEU B 165 ? VAL B 166 ? LEU B 161 VAL B 162 AB9 1 PHE B 140 ? ASP B 146 ? PHE B 136 ASP B 142 AB9 2 TYR B 186 ? LYS B 191 ? TYR B 182 LYS B 187 AB9 3 THR B 198 ? LEU B 200 ? THR B 194 LEU B 196 AC1 1 LYS B 216 ? PHE B 220 ? LYS B 212 PHE B 216 AC1 2 ALA B 243 ? PHE B 246 ? ALA B 239 PHE B 242 AC2 1 ILE B 226 ? SER B 232 ? ILE B 222 SER B 228 AC2 2 SER B 304 ? THR B 312 ? SER B 300 THR B 308 AC2 3 GLY B 290 ? ASN B 297 ? GLY B 286 ASN B 293 AC2 4 TYR B 250 ? PHE B 256 ? TYR B 246 PHE B 252 AC2 5 LYS B 263 ? ALA B 265 ? LYS B 259 ALA B 261 AC3 1 ILE B 237 ? LEU B 239 ? ILE B 233 LEU B 235 AC3 2 THR B 278 ? ILE B 281 ? THR B 274 ILE B 277 AC3 3 VAL B 272 ? VAL B 275 ? VAL B 268 VAL B 271 AC4 1 ALA B 317 ? ASP B 320 ? ALA B 313 ASP B 316 AC4 2 ALA B 332 ? TYR B 338 ? ALA B 328 TYR B 334 AC4 3 VAL B 361 ? ILE B 364 ? VAL B 357 ILE B 360 AC5 1 THR B 323 ? VAL B 326 ? THR B 319 VAL B 322 AC5 2 GLU B 384 ? LEU B 394 ? GLU B 380 LEU B 390 AC5 3 GLY B 373 ? ASN B 381 ? GLY B 369 ASN B 377 AC5 4 THR B 345 ? LYS B 350 ? THR B 341 LYS B 346 AC5 5 LYS B 353 ? ALA B 354 ? LYS B 349 ALA B 350 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N VAL A 9 ? N VAL A 5 O SER A 33 ? O SER A 29 AA2 1 2 N ILE A 18 ? N ILE A 14 O HIS A 101 ? O HIS A 97 AA2 2 3 O VAL A 100 ? O VAL A 96 N TYR A 84 ? N TYR A 80 AA2 3 4 O LEU A 87 ? O LEU A 83 N ILE A 41 ? N ILE A 37 AA3 1 2 N ILE A 18 ? N ILE A 14 O HIS A 101 ? O HIS A 97 AA3 2 3 O VAL A 100 ? O VAL A 96 N TYR A 84 ? N TYR A 80 AA3 3 4 N ALA A 88 ? N ALA A 84 O ILE A 95 ? O ILE A 91 AA4 1 2 N ALA A 26 ? N ALA A 22 O PHE A 67 ? O PHE A 63 AA4 2 3 O VAL A 66 ? O VAL A 62 N GLN A 58 ? N GLN A 54 AA5 1 2 N GLU A 113 ? N GLU A 109 O GLU A 130 ? O GLU A 126 AA6 1 2 N VAL A 119 ? N VAL A 115 O THR A 210 ? O THR A 206 AA6 2 3 O GLY A 205 ? O GLY A 201 N TYR A 186 ? N TYR A 182 AA6 3 4 O GLN A 187 ? O GLN A 183 N LEU A 145 ? N LEU A 141 AA6 4 5 N TRP A 144 ? N TRP A 140 O TYR A 152 ? O TYR A 148 AA7 1 2 N VAL A 119 ? N VAL A 115 O THR A 210 ? O THR A 206 AA7 2 3 O GLY A 205 ? O GLY A 201 N TYR A 186 ? N TYR A 182 AA7 3 4 N THR A 190 ? N THR A 186 O ARG A 199 ? O ARG A 195 AA8 1 2 N VAL A 125 ? N VAL A 121 O ILE A 174 ? O ILE A 170 AA8 2 3 O HIS A 173 ? O HIS A 169 N LEU A 165 ? N LEU A 161 AA9 1 2 N GLY A 231 ? N GLY A 227 O THR A 312 ? O THR A 308 AA9 2 3 O GLY A 301 ? O GLY A 297 N ASN A 298 ? N ASN A 294 AA9 3 4 O LYS A 291 ? O LYS A 287 N PHE A 256 ? N PHE A 252 AA9 4 5 N LYS A 255 ? N LYS A 251 O GLN A 264 ? O GLN A 260 AB1 1 2 N GLY A 231 ? N GLY A 227 O THR A 312 ? O THR A 308 AB1 2 3 N LYS A 318 ? N LYS A 314 O GLN A 337 ? O GLN A 333 AB1 3 4 N PHE A 334 ? N PHE A 330 O LEU A 362 ? O LEU A 358 AB2 1 2 N LEU A 239 ? N LEU A 235 O LEU A 279 ? O LEU A 275 AB2 2 3 O THR A 278 ? O THR A 274 N VAL A 275 ? N VAL A 271 AB3 1 2 N GLN A 324 ? N GLN A 320 O LYS A 393 ? O LYS A 389 AB3 2 3 O GLU A 384 ? O GLU A 380 N ASN A 381 ? N ASN A 377 AB3 3 4 O PHE A 378 ? O PHE A 374 N SER A 347 ? N SER A 343 AB3 4 5 N LYS A 350 ? N LYS A 346 O LYS A 353 ? O LYS A 349 AB4 1 2 N ALA B 26 ? N ALA B 22 O PHE B 67 ? O PHE B 63 AB4 2 3 O LYS B 64 ? O LYS B 60 N SER B 60 ? N SER B 56 AB5 1 2 N ILE B 41 ? N ILE B 37 O LEU B 87 ? O LEU B 83 AB5 2 3 N ASN B 90 ? N ASN B 86 O GLY B 93 ? O GLY B 89 AB6 1 2 N GLU B 113 ? N GLU B 109 O GLU B 130 ? O GLU B 126 AB7 1 2 N VAL B 119 ? N VAL B 115 O VAL B 208 ? O VAL B 204 AB8 1 2 N MET B 127 ? N MET B 123 O LEU B 172 ? O LEU B 168 AB8 2 3 O HIS B 173 ? O HIS B 169 N LEU B 165 ? N LEU B 161 AB9 1 2 N LEU B 145 ? N LEU B 141 O GLN B 187 ? O GLN B 183 AB9 2 3 N THR B 190 ? N THR B 186 O ARG B 199 ? O ARG B 195 AC1 1 2 N THR B 219 ? N THR B 215 O GLN B 244 ? O GLN B 240 AC2 1 2 N SER B 227 ? N SER B 223 O VAL B 308 ? O VAL B 304 AC2 2 3 O VAL B 305 ? O VAL B 301 N CYS B 294 ? N CYS B 290 AC2 3 4 O LYS B 291 ? O LYS B 287 N PHE B 256 ? N PHE B 252 AC2 4 5 N LYS B 255 ? N LYS B 251 O GLN B 264 ? O GLN B 260 AC3 1 2 N ILE B 237 ? N ILE B 233 O ILE B 281 ? O ILE B 277 AC3 2 3 O THR B 278 ? O THR B 274 N VAL B 275 ? N VAL B 271 AC4 1 2 N LYS B 318 ? N LYS B 314 O GLN B 337 ? O GLN B 333 AC4 2 3 N ALA B 332 ? N ALA B 328 O ILE B 364 ? O ILE B 360 AC5 1 2 N GLN B 324 ? N GLN B 320 O LYS B 393 ? O LYS B 389 AC5 2 3 O ALA B 390 ? O ALA B 386 N TYR B 375 ? N TYR B 371 AC5 3 4 O PHE B 378 ? O PHE B 374 N SER B 347 ? N SER B 343 AC5 4 5 N LYS B 350 ? N LYS B 346 O LYS B 353 ? O LYS B 349 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A ZN 407 ? 5 'binding site for residue ZN A 407' AC2 Software A ZN 408 ? 2 'binding site for residue ZN A 408' AC3 Software A ZN 409 ? 3 'binding site for residue ZN A 409' AC4 Software A ZN 410 ? 3 'binding site for residue ZN A 410' AC5 Software B ZN 404 ? 3 'binding site for residue ZN B 404' AC6 Software B ZN 405 ? 2 'binding site for residue ZN B 405' AC7 Software A ASN 18 ? 7 'binding site for Poly-Saccharide residues NAG A 401 through MAN A 404 bound to ASN A 18' AC8 Software A ASN 293 ? 3 'binding site for Poly-Saccharide residues NAG A 405 through NAG A 406 bound to ASN A 293' AC9 Software B NAG 401 ? 2 'binding site for Mono-Saccharide NAG B 401 bound to ASN B 18' AD1 Software B ASN 293 ? 4 'binding site for Poly-Saccharide residues NAG B 402 through NAG B 403 bound to ASN B 293' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 5 ASN A 16 ? ASN A 12 . ? 1_555 ? 2 AC1 5 ASP A 99 ? ASP A 95 . ? 1_555 ? 3 AC1 5 HIS A 101 ? HIS A 97 . ? 1_555 ? 4 AC1 5 ARG A 380 ? ARG A 376 . ? 1_555 ? 5 AC1 5 HOH R . ? HOH A 505 . ? 1_555 ? 6 AC2 2 GLU A 13 ? GLU A 9 . ? 1_555 ? 7 AC2 2 GLU A 387 ? GLU A 383 . ? 1_555 ? 8 AC3 3 GLU A 113 ? GLU A 109 . ? 1_555 ? 9 AC3 3 GLU A 130 ? GLU A 126 . ? 1_555 ? 10 AC3 3 ASP B 115 ? ASP B 111 . ? 1_555 ? 11 AC4 3 ASP A 115 ? ASP A 111 . ? 1_555 ? 12 AC4 3 GLU B 113 ? GLU B 109 . ? 1_555 ? 13 AC4 3 GLU B 130 ? GLU B 126 . ? 1_555 ? 14 AC5 3 ASP B 99 ? ASP B 95 . ? 1_555 ? 15 AC5 3 HIS B 101 ? HIS B 97 . ? 1_555 ? 16 AC5 3 HOH S . ? HOH B 505 . ? 1_555 ? 17 AC6 2 GLU B 13 ? GLU B 9 . ? 1_555 ? 18 AC6 2 GLU B 387 ? GLU B 383 . ? 1_555 ? 19 AC7 7 ASN A 22 ? ASN A 18 . ? 1_555 ? 20 AC7 7 SER A 23 ? SER A 19 . ? 1_555 ? 21 AC7 7 PHE A 70 ? PHE A 66 . ? 1_555 ? 22 AC7 7 ARG A 71 ? ARG A 67 . ? 1_555 ? 23 AC7 7 ALA A 72 ? ALA A 68 . ? 1_555 ? 24 AC7 7 VAL A 106 ? VAL A 102 . ? 1_555 ? 25 AC7 7 ILE A 107 ? ILE A 103 . ? 1_555 ? 26 AC8 3 ASN A 297 ? ASN A 293 . ? 1_555 ? 27 AC8 3 GLY A 302 ? GLY A 298 . ? 1_555 ? 28 AC8 3 GLU A 303 ? GLU A 299 . ? 1_555 ? 29 AC9 2 ASN B 22 ? ASN B 18 . ? 1_555 ? 30 AC9 2 ARG B 71 ? ARG B 67 . ? 1_555 ? 31 AD1 4 TYR B 250 ? TYR B 246 . ? 1_555 ? 32 AD1 4 VAL B 295 ? VAL B 291 . ? 1_555 ? 33 AD1 4 ASN B 297 ? ASN B 293 . ? 1_555 ? 34 AD1 4 GLY B 302 ? GLY B 298 . ? 1_555 ? # _atom_sites.entry_id 4XB8 _atom_sites.fract_transf_matrix[1][1] 0.014999 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000956 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.017461 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007711 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLN A 1 5 ? -43.102 22.262 -68.712 1.00 65.57 ? 1 GLN A N 1 ATOM 2 C CA . GLN A 1 5 ? -43.840 20.993 -68.448 1.00 66.13 ? 1 GLN A CA 1 ATOM 3 C C . GLN A 1 5 ? -43.390 20.349 -67.140 1.00 77.79 ? 1 GLN A C 1 ATOM 4 O O . GLN A 1 5 ? -44.104 20.405 -66.137 1.00 75.82 ? 1 GLN A O 1 ATOM 5 C CB . GLN A 1 5 ? -43.647 20.008 -69.601 1.00 74.76 ? 1 GLN A CB 1 ATOM 6 C CG . GLN A 1 5 ? -44.126 20.524 -70.945 1.00 107.38 ? 1 GLN A CG 1 ATOM 7 C CD . GLN A 1 5 ? -44.060 19.471 -72.034 1.00 99.92 ? 1 GLN A CD 1 ATOM 8 O OE1 . GLN A 1 5 ? -43.942 18.277 -71.756 1.00 92.56 ? 1 GLN A OE1 1 ATOM 9 N NE2 . GLN A 1 5 ? -44.135 19.910 -73.285 1.00 95.32 ? 1 GLN A NE2 1 ATOM 10 N N . LYS A 1 6 ? -42.203 19.744 -67.157 1.00 83.36 ? 2 LYS A N 1 ATOM 11 C CA . LYS A 1 6 ? -41.688 19.025 -65.995 1.00 75.28 ? 2 LYS A CA 1 ATOM 12 C C . LYS A 1 6 ? -40.453 19.700 -65.413 1.00 74.49 ? 2 LYS A C 1 ATOM 13 O O . LYS A 1 6 ? -39.933 20.660 -65.978 1.00 68.10 ? 2 LYS A O 1 ATOM 14 C CB . LYS A 1 6 ? -41.355 17.579 -66.376 1.00 67.60 ? 2 LYS A CB 1 ATOM 15 C CG . LYS A 1 6 ? -42.555 16.758 -66.815 1.00 96.03 ? 2 LYS A CG 1 ATOM 16 C CD . LYS A 1 6 ? -43.556 16.589 -65.683 1.00 95.05 ? 2 LYS A CD 1 ATOM 17 C CE . LYS A 1 6 ? -44.777 15.811 -66.131 1.00 81.00 ? 2 LYS A CE 1 ATOM 18 N NZ . LYS A 1 6 ? -45.842 15.823 -65.092 1.00 89.33 ? 2 LYS A NZ 1 ATOM 19 N N . GLY A 1 7 ? -39.976 19.161 -64.295 1.00 82.75 ? 3 GLY A N 1 ATOM 20 C CA . GLY A 1 7 ? -38.830 19.712 -63.598 1.00 54.39 ? 3 GLY A CA 1 ATOM 21 C C . GLY A 1 7 ? -37.566 18.969 -63.971 1.00 71.12 ? 3 GLY A C 1 ATOM 22 O O . GLY A 1 7 ? -37.618 17.986 -64.712 1.00 69.52 ? 3 GLY A O 1 ATOM 23 N N . PRO A 1 8 ? -36.417 19.427 -63.457 1.00 75.10 ? 4 PRO A N 1 ATOM 24 C CA . PRO A 1 8 ? -35.158 18.751 -63.768 1.00 55.24 ? 4 PRO A CA 1 ATOM 25 C C . PRO A 1 8 ? -35.114 17.361 -63.152 1.00 61.14 ? 4 PRO A C 1 ATOM 26 O O . PRO A 1 8 ? -35.433 17.205 -61.972 1.00 60.46 ? 4 PRO A O 1 ATOM 27 C CB . PRO A 1 8 ? -34.107 19.667 -63.146 1.00 39.13 ? 4 PRO A CB 1 ATOM 28 C CG . PRO A 1 8 ? -34.814 20.286 -61.978 1.00 39.56 ? 4 PRO A CG 1 ATOM 29 C CD . PRO A 1 8 ? -36.247 20.463 -62.423 1.00 60.15 ? 4 PRO A CD 1 ATOM 30 N N . VAL A 1 9 ? -34.736 16.369 -63.950 1.00 60.60 ? 5 VAL A N 1 ATOM 31 C CA . VAL A 1 9 ? -34.550 15.014 -63.456 1.00 49.48 ? 5 VAL A CA 1 ATOM 32 C C . VAL A 1 9 ? -33.127 14.591 -63.779 1.00 57.72 ? 5 VAL A C 1 ATOM 33 O O . VAL A 1 9 ? -32.647 14.795 -64.893 1.00 56.86 ? 5 VAL A O 1 ATOM 34 C CB . VAL A 1 9 ? -35.570 14.023 -64.068 1.00 52.44 ? 5 VAL A CB 1 ATOM 35 C CG1 . VAL A 1 9 ? -35.397 13.907 -65.585 1.00 48.72 ? 5 VAL A CG1 1 ATOM 36 C CG2 . VAL A 1 9 ? -35.456 12.658 -63.397 1.00 49.33 ? 5 VAL A CG2 1 ATOM 37 N N . PHE A 1 10 ? -32.447 14.025 -62.790 1.00 57.14 ? 6 PHE A N 1 ATOM 38 C CA . PHE A 1 10 ? -31.066 13.605 -62.965 1.00 48.40 ? 6 PHE A CA 1 ATOM 39 C C . PHE A 1 10 ? -30.989 12.279 -63.713 1.00 59.38 ? 6 PHE A C 1 ATOM 40 O O . PHE A 1 10 ? -31.618 11.294 -63.322 1.00 67.08 ? 6 PHE A O 1 ATOM 41 C CB . PHE A 1 10 ? -30.368 13.491 -61.606 1.00 55.24 ? 6 PHE A CB 1 ATOM 42 C CG . PHE A 1 10 ? -29.561 14.709 -61.226 1.00 53.87 ? 6 PHE A CG 1 ATOM 43 C CD1 . PHE A 1 10 ? -28.672 15.281 -62.118 1.00 38.77 ? 6 PHE A CD1 1 ATOM 44 C CD2 . PHE A 1 10 ? -29.693 15.278 -59.971 1.00 49.22 ? 6 PHE A CD2 1 ATOM 45 C CE1 . PHE A 1 10 ? -27.937 16.392 -61.767 1.00 23.50 ? 6 PHE A CE1 1 ATOM 46 C CE2 . PHE A 1 10 ? -28.954 16.390 -59.617 1.00 34.53 ? 6 PHE A CE2 1 ATOM 47 C CZ . PHE A 1 10 ? -28.077 16.945 -60.516 1.00 29.38 ? 6 PHE A CZ 1 ATOM 48 N N . LEU A 1 11 ? -30.217 12.272 -64.794 1.00 56.53 ? 7 LEU A N 1 ATOM 49 C CA . LEU A 1 11 ? -30.003 11.069 -65.588 1.00 62.55 ? 7 LEU A CA 1 ATOM 50 C C . LEU A 1 11 ? -28.650 10.467 -65.252 1.00 55.29 ? 7 LEU A C 1 ATOM 51 O O . LEU A 1 11 ? -28.565 9.432 -64.591 1.00 65.02 ? 7 LEU A O 1 ATOM 52 C CB . LEU A 1 11 ? -30.081 11.385 -67.082 1.00 53.01 ? 7 LEU A CB 1 ATOM 53 C CG . LEU A 1 11 ? -31.424 11.921 -67.572 1.00 46.64 ? 7 LEU A CG 1 ATOM 54 C CD1 . LEU A 1 11 ? -31.314 12.321 -69.032 1.00 58.25 ? 7 LEU A CD1 1 ATOM 55 C CD2 . LEU A 1 11 ? -32.524 10.888 -67.368 1.00 49.83 ? 7 LEU A CD2 1 ATOM 56 N N . LYS A 1 12 ? -27.597 11.137 -65.706 1.00 53.13 ? 8 LYS A N 1 ATOM 57 C CA . LYS A 1 12 ? -26.236 10.703 -65.444 1.00 58.30 ? 8 LYS A CA 1 ATOM 58 C C . LYS A 1 12 ? -25.625 11.605 -64.378 1.00 56.27 ? 8 LYS A C 1 ATOM 59 O O . LYS A 1 12 ? -25.418 12.796 -64.608 1.00 65.12 ? 8 LYS A O 1 ATOM 60 C CB . LYS A 1 12 ? -25.407 10.730 -66.733 1.00 59.31 ? 8 LYS A CB 1 ATOM 61 C CG . LYS A 1 12 ? -24.064 10.029 -66.631 1.00 78.86 ? 8 LYS A CG 1 ATOM 62 C CD . LYS A 1 12 ? -22.960 10.988 -66.225 1.00 67.42 ? 8 LYS A CD 1 ATOM 63 C CE . LYS A 1 12 ? -21.634 10.270 -66.064 1.00 62.39 ? 8 LYS A CE 1 ATOM 64 N NZ . LYS A 1 12 ? -20.617 11.130 -65.400 1.00 69.82 ? 8 LYS A NZ 1 ATOM 65 N N . GLU A 1 13 ? -25.348 11.027 -63.213 1.00 50.67 ? 9 GLU A N 1 ATOM 66 C CA . GLU A 1 13 ? -24.700 11.743 -62.121 1.00 43.63 ? 9 GLU A CA 1 ATOM 67 C C . GLU A 1 13 ? -23.301 11.154 -61.964 1.00 63.96 ? 9 GLU A C 1 ATOM 68 O O . GLU A 1 13 ? -23.091 9.980 -62.271 1.00 72.66 ? 9 GLU A O 1 ATOM 69 C CB . GLU A 1 13 ? -25.491 11.600 -60.810 1.00 39.73 ? 9 GLU A CB 1 ATOM 70 C CG . GLU A 1 13 ? -26.964 12.004 -60.877 1.00 47.97 ? 9 GLU A CG 1 ATOM 71 C CD . GLU A 1 13 ? -27.804 11.389 -59.748 1.00 61.85 ? 9 GLU A CD 1 ATOM 72 O OE1 . GLU A 1 13 ? -27.741 11.884 -58.605 1.00 52.11 ? 9 GLU A OE1 1 ATOM 73 O OE2 . GLU A 1 13 ? -28.534 10.405 -59.999 1.00 57.08 ? 9 GLU A OE2 1 ATOM 74 N N . PRO A 1 14 ? -22.330 11.959 -61.501 1.00 61.38 ? 10 PRO A N 1 ATOM 75 C CA . PRO A 1 14 ? -21.025 11.350 -61.220 1.00 53.08 ? 10 PRO A CA 1 ATOM 76 C C . PRO A 1 14 ? -21.086 10.382 -60.043 1.00 42.55 ? 10 PRO A C 1 ATOM 77 O O . PRO A 1 14 ? -22.161 10.149 -59.487 1.00 43.05 ? 10 PRO A O 1 ATOM 78 C CB . PRO A 1 14 ? -20.131 12.550 -60.891 1.00 60.05 ? 10 PRO A CB 1 ATOM 79 C CG . PRO A 1 14 ? -20.801 13.723 -61.515 1.00 65.87 ? 10 PRO A CG 1 ATOM 80 C CD . PRO A 1 14 ? -22.274 13.431 -61.468 1.00 65.30 ? 10 PRO A CD 1 ATOM 81 N N . THR A 1 15 ? -19.934 9.841 -59.664 1.00 38.57 ? 11 THR A N 1 ATOM 82 C CA . THR A 1 15 ? -19.860 8.837 -58.612 1.00 40.39 ? 11 THR A CA 1 ATOM 83 C C . THR A 1 15 ? -19.332 9.460 -57.327 1.00 44.69 ? 11 THR A C 1 ATOM 84 O O . THR A 1 15 ? -18.541 10.403 -57.365 1.00 45.62 ? 11 THR A O 1 ATOM 85 C CB . THR A 1 15 ? -18.956 7.657 -59.018 1.00 49.35 ? 11 THR A CB 1 ATOM 86 O OG1 . THR A 1 15 ? -17.588 7.968 -58.725 1.00 65.54 ? 11 THR A OG1 1 ATOM 87 C CG2 . THR A 1 15 ? -19.112 7.342 -60.504 1.00 38.25 ? 11 THR A CG2 1 ATOM 88 N N . ASN A 1 16 ? -19.785 8.927 -56.196 1.00 43.89 ? 12 ASN A N 1 ATOM 89 C CA . ASN A 1 16 ? -19.431 9.455 -54.884 1.00 43.54 ? 12 ASN A CA 1 ATOM 90 C C . ASN A 1 16 ? -17.934 9.679 -54.704 1.00 40.87 ? 12 ASN A C 1 ATOM 91 O O . ASN A 1 16 ? -17.522 10.638 -54.052 1.00 45.15 ? 12 ASN A O 1 ATOM 92 C CB . ASN A 1 16 ? -19.929 8.511 -53.791 1.00 46.95 ? 12 ASN A CB 1 ATOM 93 C CG . ASN A 1 16 ? -20.979 9.145 -52.911 1.00 51.02 ? 12 ASN A CG 1 ATOM 94 O OD1 . ASN A 1 16 ? -22.176 8.990 -53.145 1.00 46.83 ? 12 ASN A OD1 1 ATOM 95 N ND2 . ASN A 1 16 ? -20.536 9.868 -51.890 1.00 52.43 ? 12 ASN A ND2 1 ATOM 96 N N . ARG A 1 17 ? -17.130 8.791 -55.281 1.00 43.27 ? 13 ARG A N 1 ATOM 97 C CA . ARG A 1 17 ? -15.677 8.903 -55.212 1.00 41.18 ? 13 ARG A CA 1 ATOM 98 C C . ARG A 1 17 ? -15.054 8.923 -56.604 1.00 35.83 ? 13 ARG A C 1 ATOM 99 O O . ARG A 1 17 ? -15.188 7.968 -57.368 1.00 34.57 ? 13 ARG A O 1 ATOM 100 C CB . ARG A 1 17 ? -15.089 7.753 -54.396 1.00 38.99 ? 13 ARG A CB 1 ATOM 101 C CG . ARG A 1 17 ? -14.599 8.169 -53.016 1.00 41.60 ? 13 ARG A CG 1 ATOM 102 C CD . ARG A 1 17 ? -15.750 8.318 -52.030 1.00 40.39 ? 13 ARG A CD 1 ATOM 103 N NE . ARG A 1 17 ? -15.294 8.782 -50.721 1.00 47.25 ? 13 ARG A NE 1 ATOM 104 C CZ . ARG A 1 17 ? -16.070 8.878 -49.645 1.00 49.00 ? 13 ARG A CZ 1 ATOM 105 N NH1 . ARG A 1 17 ? -17.350 8.538 -49.707 1.00 47.13 ? 13 ARG A NH1 1 ATOM 106 N NH2 . ARG A 1 17 ? -15.563 9.312 -48.501 1.00 58.25 ? 13 ARG A NH2 1 ATOM 107 N N . ILE A 1 18 ? -14.377 10.024 -56.921 1.00 45.38 ? 14 ILE A N 1 ATOM 108 C CA . ILE A 1 18 ? -13.645 10.157 -58.177 1.00 44.95 ? 14 ILE A CA 1 ATOM 109 C C . ILE A 1 18 ? -12.169 10.378 -57.877 1.00 42.75 ? 14 ILE A C 1 ATOM 110 O O . ILE A 1 18 ? -11.787 11.408 -57.323 1.00 45.58 ? 14 ILE A O 1 ATOM 111 C CB . ILE A 1 18 ? -14.176 11.322 -59.039 1.00 39.79 ? 14 ILE A CB 1 ATOM 112 C CG1 . ILE A 1 18 ? -15.649 11.095 -59.394 1.00 40.99 ? 14 ILE A CG1 1 ATOM 113 C CG2 . ILE A 1 18 ? -13.329 11.483 -60.306 1.00 38.54 ? 14 ILE A CG2 1 ATOM 114 C CD1 . ILE A 1 18 ? -15.904 9.855 -60.241 1.00 62.96 ? 14 ILE A CD1 1 ATOM 115 N N . ASP A 1 19 ? -11.348 9.400 -58.245 1.00 42.16 ? 15 ASP A N 1 ATOM 116 C CA . ASP A 1 19 ? -9.920 9.449 -57.971 1.00 33.51 ? 15 ASP A CA 1 ATOM 117 C C . ASP A 1 19 ? -9.134 9.396 -59.274 1.00 40.10 ? 15 ASP A C 1 ATOM 118 O O . ASP A 1 19 ? -9.485 8.647 -60.187 1.00 32.13 ? 15 ASP A O 1 ATOM 119 C CB . ASP A 1 19 ? -9.506 8.292 -57.059 1.00 35.41 ? 15 ASP A CB 1 ATOM 120 C CG . ASP A 1 19 ? -10.423 8.132 -55.863 1.00 52.19 ? 15 ASP A CG 1 ATOM 121 O OD1 . ASP A 1 19 ? -11.135 9.098 -55.519 1.00 52.87 ? 15 ASP A OD1 1 ATOM 122 O OD2 . ASP A 1 19 ? -10.426 7.041 -55.256 1.00 74.84 ? 15 ASP A OD2 1 ATOM 123 N N . PHE A 1 20 ? -8.077 10.197 -59.359 1.00 34.92 ? 16 PHE A N 1 ATOM 124 C CA . PHE A 1 20 ? -7.202 10.179 -60.524 1.00 34.81 ? 16 PHE A CA 1 ATOM 125 C C . PHE A 1 20 ? -5.819 10.719 -60.180 1.00 45.02 ? 16 PHE A C 1 ATOM 126 O O . PHE A 1 20 ? -5.566 11.126 -59.044 1.00 48.74 ? 16 PHE A O 1 ATOM 127 C CB . PHE A 1 20 ? -7.818 10.985 -61.669 1.00 37.64 ? 16 PHE A CB 1 ATOM 128 C CG . PHE A 1 20 ? -8.020 12.445 -61.352 1.00 51.47 ? 16 PHE A CG 1 ATOM 129 C CD1 . PHE A 1 20 ? -9.093 12.863 -60.582 1.00 42.40 ? 16 PHE A CD1 1 ATOM 130 C CD2 . PHE A 1 20 ? -7.142 13.402 -61.835 1.00 57.26 ? 16 PHE A CD2 1 ATOM 131 C CE1 . PHE A 1 20 ? -9.279 14.204 -60.296 1.00 40.80 ? 16 PHE A CE1 1 ATOM 132 C CE2 . PHE A 1 20 ? -7.327 14.742 -61.550 1.00 44.45 ? 16 PHE A CE2 1 ATOM 133 C CZ . PHE A 1 20 ? -8.396 15.141 -60.782 1.00 37.02 ? 16 PHE A CZ 1 ATOM 134 N N . SER A 1 21 ? -4.934 10.730 -61.173 1.00 45.22 ? 17 SER A N 1 ATOM 135 C CA . SER A 1 21 ? -3.539 11.098 -60.960 1.00 43.67 ? 17 SER A CA 1 ATOM 136 C C . SER A 1 21 ? -3.201 12.400 -61.669 1.00 68.47 ? 17 SER A C 1 ATOM 137 O O . SER A 1 21 ? -3.845 12.769 -62.651 1.00 53.09 ? 17 SER A O 1 ATOM 138 C CB . SER A 1 21 ? -2.610 9.985 -61.448 1.00 50.46 ? 17 SER A CB 1 ATOM 139 O OG . SER A 1 21 ? -2.468 10.017 -62.855 1.00 47.30 ? 17 SER A OG 1 ATOM 140 N N . ASN A 1 22 ? -2.190 13.092 -61.154 1.00 51.71 ? 18 ASN A N 1 ATOM 141 C CA . ASN A 1 22 ? -1.786 14.383 -61.692 1.00 35.80 ? 18 ASN A CA 1 ATOM 142 C C . ASN A 1 22 ? -1.369 14.291 -63.157 1.00 35.79 ? 18 ASN A C 1 ATOM 143 O O . ASN A 1 22 ? -1.410 15.282 -63.880 1.00 51.28 ? 18 ASN A O 1 ATOM 144 C CB . ASN A 1 22 ? -0.640 14.969 -60.859 1.00 40.56 ? 18 ASN A CB 1 ATOM 145 C CG . ASN A 1 22 ? 0.662 14.212 -61.048 1.00 55.52 ? 18 ASN A CG 1 ATOM 146 O OD1 . ASN A 1 22 ? 0.668 12.984 -61.121 1.00 63.01 ? 18 ASN A OD1 1 ATOM 147 N ND2 . ASN A 1 22 ? 1.773 14.943 -61.132 1.00 40.70 ? 18 ASN A ND2 1 ATOM 148 N N . SER A 1 23 ? -0.960 13.102 -63.587 1.00 35.22 ? 19 SER A N 1 ATOM 149 C CA . SER A 1 23 ? -0.566 12.878 -64.976 1.00 45.79 ? 19 SER A CA 1 ATOM 150 C C . SER A 1 23 ? -1.777 12.666 -65.885 1.00 44.16 ? 19 SER A C 1 ATOM 151 O O . SER A 1 23 ? -1.774 13.079 -67.046 1.00 52.78 ? 19 SER A O 1 ATOM 152 C CB . SER A 1 23 ? 0.374 11.675 -65.076 1.00 55.36 ? 19 SER A CB 1 ATOM 153 O OG . SER A 1 23 ? 1.557 11.884 -64.322 1.00 46.96 ? 19 SER A OG 1 ATOM 154 N N . THR A 1 24 ? -2.807 12.016 -65.352 1.00 47.79 ? 20 THR A N 1 ATOM 155 C CA . THR A 1 24 ? -4.009 11.711 -66.121 1.00 51.22 ? 20 THR A CA 1 ATOM 156 C C . THR A 1 24 ? -4.913 12.929 -66.223 1.00 47.35 ? 20 THR A C 1 ATOM 157 O O . THR A 1 24 ? -5.115 13.481 -67.306 1.00 54.61 ? 20 THR A O 1 ATOM 158 C CB . THR A 1 24 ? -4.817 10.553 -65.490 1.00 53.13 ? 20 THR A CB 1 ATOM 159 O OG1 . THR A 1 24 ? -5.084 10.844 -64.111 1.00 57.84 ? 20 THR A OG1 1 ATOM 160 C CG2 . THR A 1 24 ? -4.058 9.237 -65.599 1.00 53.60 ? 20 THR A CG2 1 ATOM 161 N N . GLY A 1 25 ? -5.448 13.341 -65.080 1.00 51.83 ? 21 GLY A N 1 ATOM 162 C CA . GLY A 1 25 ? -6.443 14.393 -65.031 1.00 47.23 ? 21 GLY A CA 1 ATOM 163 C C . GLY A 1 25 ? -7.817 13.758 -65.040 1.00 56.53 ? 21 GLY A C 1 ATOM 164 O O . GLY A 1 25 ? -7.937 12.532 -65.053 1.00 51.91 ? 21 GLY A O 1 ATOM 165 N N . ALA A 1 26 ? -8.855 14.585 -65.023 1.00 62.45 ? 22 ALA A N 1 ATOM 166 C CA . ALA A 1 26 ? -10.219 14.081 -65.025 1.00 46.26 ? 22 ALA A CA 1 ATOM 167 C C . ALA A 1 26 ? -11.166 15.086 -65.658 1.00 41.49 ? 22 ALA A C 1 ATOM 168 O O . ALA A 1 26 ? -10.949 16.294 -65.575 1.00 54.15 ? 22 ALA A O 1 ATOM 169 C CB . ALA A 1 26 ? -10.665 13.754 -63.606 1.00 40.27 ? 22 ALA A CB 1 ATOM 170 N N . GLU A 1 27 ? -12.208 14.573 -66.302 1.00 55.37 ? 23 GLU A N 1 ATOM 171 C CA . GLU A 1 27 ? -13.321 15.394 -66.754 1.00 51.47 ? 23 GLU A CA 1 ATOM 172 C C . GLU A 1 27 ? -14.605 14.671 -66.376 1.00 50.80 ? 23 GLU A C 1 ATOM 173 O O . GLU A 1 27 ? -14.837 13.534 -66.791 1.00 63.17 ? 23 GLU A O 1 ATOM 174 C CB . GLU A 1 27 ? -13.244 15.661 -68.262 1.00 50.51 ? 23 GLU A CB 1 ATOM 175 C CG . GLU A 1 27 ? -13.352 14.426 -69.143 1.00 79.65 ? 23 GLU A CG 1 ATOM 176 C CD . GLU A 1 27 ? -13.101 14.726 -70.609 1.00 94.30 ? 23 GLU A CD 1 ATOM 177 O OE1 . GLU A 1 27 ? -12.179 15.513 -70.913 1.00 95.13 ? 23 GLU A OE1 1 ATOM 178 O OE2 . GLU A 1 27 ? -13.830 14.174 -71.461 1.00 98.87 ? 23 GLU A OE2 1 ATOM 179 N N . ILE A 1 28 ? -15.424 15.328 -65.561 1.00 45.78 ? 24 ILE A N 1 ATOM 180 C CA . ILE A 1 28 ? -16.625 14.703 -65.023 1.00 60.09 ? 24 ILE A CA 1 ATOM 181 C C . ILE A 1 28 ? -17.876 15.351 -65.605 1.00 50.53 ? 24 ILE A C 1 ATOM 182 O O . ILE A 1 28 ? -17.894 16.549 -65.891 1.00 38.33 ? 24 ILE A O 1 ATOM 183 C CB . ILE A 1 28 ? -16.647 14.777 -63.484 1.00 49.92 ? 24 ILE A CB 1 ATOM 184 C CG1 . ILE A 1 28 ? -16.696 16.229 -63.002 1.00 35.99 ? 24 ILE A CG1 1 ATOM 185 C CG2 . ILE A 1 28 ? -15.418 14.064 -62.919 1.00 47.67 ? 24 ILE A CG2 1 ATOM 186 C CD1 . ILE A 1 28 ? -16.857 16.365 -61.503 1.00 44.10 ? 24 ILE A CD1 1 ATOM 187 N N . GLU A 1 29 ? -18.916 14.540 -65.776 1.00 59.34 ? 25 GLU A N 1 ATOM 188 C CA . GLU A 1 29 ? -20.120 14.956 -66.482 1.00 45.36 ? 25 GLU A CA 1 ATOM 189 C C . GLU A 1 29 ? -21.346 14.881 -65.590 1.00 39.90 ? 25 GLU A C 1 ATOM 190 O O . GLU A 1 29 ? -21.414 14.064 -64.673 1.00 43.08 ? 25 GLU A O 1 ATOM 191 C CB . GLU A 1 29 ? -20.326 14.083 -67.719 1.00 53.84 ? 25 GLU A CB 1 ATOM 192 C CG . GLU A 1 29 ? -21.344 14.620 -68.705 1.00 62.51 ? 25 GLU A CG 1 ATOM 193 C CD . GLU A 1 29 ? -21.500 13.720 -69.916 1.00 80.40 ? 25 GLU A CD 1 ATOM 194 O OE1 . GLU A 1 29 ? -20.950 14.061 -70.985 1.00 75.76 ? 25 GLU A OE1 1 ATOM 195 O OE2 . GLU A 1 29 ? -22.169 12.671 -69.796 1.00 81.23 ? 25 GLU A OE2 1 ATOM 196 N N . CYS A 1 30 ? -22.315 15.743 -65.872 1.00 54.59 ? 26 CYS A N 1 ATOM 197 C CA . CYS A 1 30 ? -23.590 15.727 -65.173 1.00 57.74 ? 26 CYS A CA 1 ATOM 198 C C . CYS A 1 30 ? -24.708 15.989 -66.175 1.00 55.02 ? 26 CYS A C 1 ATOM 199 O O . CYS A 1 30 ? -24.597 16.885 -67.013 1.00 60.55 ? 26 CYS A O 1 ATOM 200 C CB . CYS A 1 30 ? -23.601 16.766 -64.056 1.00 55.43 ? 26 CYS A CB 1 ATOM 201 S SG . CYS A 1 30 ? -24.787 16.416 -62.749 1.00 54.10 ? 26 CYS A SG 1 ATOM 202 N N . LYS A 1 31 ? -25.778 15.204 -66.088 1.00 53.31 ? 27 LYS A N 1 ATOM 203 C CA . LYS A 1 31 ? -26.853 15.261 -67.074 1.00 61.86 ? 27 LYS A CA 1 ATOM 204 C C . LYS A 1 31 ? -28.221 15.353 -66.415 1.00 65.63 ? 27 LYS A C 1 ATOM 205 O O . LYS A 1 31 ? -28.540 14.589 -65.501 1.00 65.13 ? 27 LYS A O 1 ATOM 206 C CB . LYS A 1 31 ? -26.791 14.038 -67.991 1.00 60.89 ? 27 LYS A CB 1 ATOM 207 C CG . LYS A 1 31 ? -25.652 14.099 -68.989 1.00 75.38 ? 27 LYS A CG 1 ATOM 208 C CD . LYS A 1 31 ? -26.046 14.905 -70.213 1.00 80.68 ? 27 LYS A CD 1 ATOM 209 C CE . LYS A 1 31 ? -24.835 15.523 -70.888 1.00 65.94 ? 27 LYS A CE 1 ATOM 210 N NZ . LYS A 1 31 ? -24.305 16.676 -70.107 1.00 74.25 ? 27 LYS A NZ 1 ATOM 211 N N . ALA A 1 32 ? -29.019 16.303 -66.890 1.00 65.47 ? 28 ALA A N 1 ATOM 212 C CA . ALA A 1 32 ? -30.375 16.500 -66.397 1.00 59.42 ? 28 ALA A CA 1 ATOM 213 C C . ALA A 1 32 ? -31.306 16.823 -67.559 1.00 61.34 ? 28 ALA A C 1 ATOM 214 O O . ALA A 1 32 ? -30.863 17.313 -68.599 1.00 67.72 ? 28 ALA A O 1 ATOM 215 C CB . ALA A 1 32 ? -30.409 17.610 -65.354 1.00 53.65 ? 28 ALA A CB 1 ATOM 216 N N . SER A 1 33 ? -32.593 16.541 -67.379 1.00 69.61 ? 29 SER A N 1 ATOM 217 C CA . SER A 1 33 ? -33.583 16.780 -68.423 1.00 76.27 ? 29 SER A CA 1 ATOM 218 C C . SER A 1 33 ? -34.873 17.344 -67.842 1.00 64.47 ? 29 SER A C 1 ATOM 219 O O . SER A 1 33 ? -35.174 17.156 -66.663 1.00 63.65 ? 29 SER A O 1 ATOM 220 C CB . SER A 1 33 ? -33.877 15.489 -69.189 1.00 64.72 ? 29 SER A CB 1 ATOM 221 O OG . SER A 1 33 ? -34.650 15.753 -70.347 1.00 75.01 ? 29 SER A OG 1 ATOM 222 N N . GLY A 1 34 ? -35.631 18.037 -68.683 1.00 52.95 ? 30 GLY A N 1 ATOM 223 C CA . GLY A 1 34 ? -36.894 18.624 -68.280 1.00 70.33 ? 30 GLY A CA 1 ATOM 224 C C . GLY A 1 34 ? -37.282 19.737 -69.231 1.00 70.89 ? 30 GLY A C 1 ATOM 225 O O . GLY A 1 34 ? -36.496 20.116 -70.098 1.00 66.37 ? 30 GLY A O 1 ATOM 226 N N . ASN A 1 35 ? -38.501 20.247 -69.080 1.00 61.57 ? 31 ASN A N 1 ATOM 227 C CA . ASN A 1 35 ? -38.979 21.357 -69.898 1.00 55.58 ? 31 ASN A CA 1 ATOM 228 C C . ASN A 1 35 ? -39.302 22.587 -69.043 1.00 57.88 ? 31 ASN A C 1 ATOM 229 O O . ASN A 1 35 ? -40.219 22.537 -68.227 1.00 62.10 ? 31 ASN A O 1 ATOM 230 C CB . ASN A 1 35 ? -40.212 20.929 -70.692 1.00 68.43 ? 31 ASN A CB 1 ATOM 231 C CG . ASN A 1 35 ? -40.254 21.546 -72.075 1.00 70.86 ? 31 ASN A CG 1 ATOM 232 O OD1 . ASN A 1 35 ? -39.882 22.705 -72.261 1.00 67.29 ? 31 ASN A OD1 1 ATOM 233 N ND2 . ASN A 1 35 ? -40.696 20.770 -73.058 1.00 69.83 ? 31 ASN A ND2 1 ATOM 234 N N . PRO A 1 36 ? -38.558 23.697 -69.222 1.00 64.79 ? 32 PRO A N 1 ATOM 235 C CA . PRO A 1 36 ? -37.430 23.873 -70.146 1.00 67.85 ? 32 PRO A CA 1 ATOM 236 C C . PRO A 1 36 ? -36.191 23.116 -69.674 1.00 72.14 ? 32 PRO A C 1 ATOM 237 O O . PRO A 1 36 ? -36.068 22.837 -68.481 1.00 62.45 ? 32 PRO A O 1 ATOM 238 C CB . PRO A 1 36 ? -37.185 25.390 -70.133 1.00 67.23 ? 32 PRO A CB 1 ATOM 239 C CG . PRO A 1 36 ? -38.351 25.995 -69.401 1.00 61.10 ? 32 PRO A CG 1 ATOM 240 C CD . PRO A 1 36 ? -38.839 24.935 -68.478 1.00 62.73 ? 32 PRO A CD 1 ATOM 241 N N . MET A 1 37 ? -35.291 22.790 -70.598 1.00 76.60 ? 33 MET A N 1 ATOM 242 C CA . MET A 1 37 ? -34.073 22.061 -70.257 1.00 61.80 ? 33 MET A CA 1 ATOM 243 C C . MET A 1 37 ? -33.230 22.836 -69.248 1.00 70.11 ? 33 MET A C 1 ATOM 244 O O . MET A 1 37 ? -32.935 24.013 -69.458 1.00 79.78 ? 33 MET A O 1 ATOM 245 C CB . MET A 1 37 ? -33.250 21.776 -71.512 1.00 49.41 ? 33 MET A CB 1 ATOM 246 C CG . MET A 1 37 ? -31.808 21.398 -71.238 1.00 75.30 ? 33 MET A CG 1 ATOM 247 S SD . MET A 1 37 ? -31.084 20.476 -72.607 1.00 106.25 ? 33 MET A SD 1 ATOM 248 C CE . MET A 1 37 ? -31.588 21.485 -73.997 1.00 70.61 ? 33 MET A CE 1 ATOM 249 N N . PRO A 1 38 ? -32.837 22.178 -68.145 1.00 54.42 ? 34 PRO A N 1 ATOM 250 C CA . PRO A 1 38 ? -32.057 22.886 -67.127 1.00 53.31 ? 34 PRO A CA 1 ATOM 251 C C . PRO A 1 38 ? -30.612 23.112 -67.547 1.00 58.58 ? 34 PRO A C 1 ATOM 252 O O . PRO A 1 38 ? -30.126 22.456 -68.469 1.00 64.55 ? 34 PRO A O 1 ATOM 253 C CB . PRO A 1 38 ? -32.133 21.953 -65.919 1.00 51.59 ? 34 PRO A CB 1 ATOM 254 C CG . PRO A 1 38 ? -32.261 20.592 -66.518 1.00 52.54 ? 34 PRO A CG 1 ATOM 255 C CD . PRO A 1 38 ? -33.075 20.771 -67.774 1.00 50.95 ? 34 PRO A CD 1 ATOM 256 N N . GLU A 1 39 ? -29.946 24.044 -66.872 1.00 57.05 ? 35 GLU A N 1 ATOM 257 C CA . GLU A 1 39 ? -28.534 24.311 -67.102 1.00 61.17 ? 35 GLU A CA 1 ATOM 258 C C . GLU A 1 39 ? -27.736 23.777 -65.922 1.00 63.39 ? 35 GLU A C 1 ATOM 259 O O . GLU A 1 39 ? -28.102 23.988 -64.764 1.00 55.39 ? 35 GLU A O 1 ATOM 260 C CB . GLU A 1 39 ? -28.288 25.808 -67.299 1.00 76.92 ? 35 GLU A CB 1 ATOM 261 C CG . GLU A 1 39 ? -28.816 26.684 -66.176 1.00 84.00 ? 35 GLU A CG 1 ATOM 262 C CD . GLU A 1 39 ? -28.642 28.162 -66.464 1.00 99.72 ? 35 GLU A CD 1 ATOM 263 O OE1 . GLU A 1 39 ? -28.103 28.501 -67.538 1.00 110.31 ? 35 GLU A OE1 1 ATOM 264 O OE2 . GLU A 1 39 ? -29.046 28.986 -65.617 1.00 97.01 ? 35 GLU A OE2 1 ATOM 265 N N . ILE A 1 40 ? -26.649 23.077 -66.223 1.00 59.89 ? 36 ILE A N 1 ATOM 266 C CA . ILE A 1 40 ? -25.879 22.391 -65.198 1.00 59.94 ? 36 ILE A CA 1 ATOM 267 C C . ILE A 1 40 ? -24.825 23.319 -64.606 1.00 59.86 ? 36 ILE A C 1 ATOM 268 O O . ILE A 1 40 ? -23.974 23.848 -65.321 1.00 61.41 ? 36 ILE A O 1 ATOM 269 C CB . ILE A 1 40 ? -25.208 21.121 -65.760 1.00 64.53 ? 36 ILE A CB 1 ATOM 270 C CG1 . ILE A 1 40 ? -26.274 20.074 -66.099 1.00 67.31 ? 36 ILE A CG1 1 ATOM 271 C CG2 . ILE A 1 40 ? -24.225 20.539 -64.754 1.00 61.64 ? 36 ILE A CG2 1 ATOM 272 C CD1 . ILE A 1 40 ? -26.913 20.243 -67.466 1.00 79.39 ? 36 ILE A CD1 1 ATOM 273 N N . ILE A 1 41 ? -24.898 23.505 -63.291 1.00 47.73 ? 37 ILE A N 1 ATOM 274 C CA . ILE A 1 41 ? -23.969 24.367 -62.570 1.00 40.58 ? 37 ILE A CA 1 ATOM 275 C C . ILE A 1 41 ? -23.182 23.554 -61.553 1.00 41.03 ? 37 ILE A C 1 ATOM 276 O O . ILE A 1 41 ? -23.752 22.788 -60.773 1.00 37.42 ? 37 ILE A O 1 ATOM 277 C CB . ILE A 1 41 ? -24.708 25.521 -61.860 1.00 36.52 ? 37 ILE A CB 1 ATOM 278 C CG1 . ILE A 1 41 ? -25.336 26.452 -62.899 1.00 44.29 ? 37 ILE A CG1 1 ATOM 279 C CG2 . ILE A 1 41 ? -23.754 26.308 -60.956 1.00 36.26 ? 37 ILE A CG2 1 ATOM 280 C CD1 . ILE A 1 41 ? -26.346 27.421 -62.326 1.00 63.62 ? 37 ILE A CD1 1 ATOM 281 N N . TRP A 1 42 ? -21.865 23.735 -61.570 1.00 49.88 ? 38 TRP A N 1 ATOM 282 C CA . TRP A 1 42 ? -20.970 23.013 -60.675 1.00 36.55 ? 38 TRP A CA 1 ATOM 283 C C . TRP A 1 42 ? -20.740 23.800 -59.399 1.00 37.57 ? 38 TRP A C 1 ATOM 284 O O . TRP A 1 42 ? -20.585 25.022 -59.426 1.00 54.69 ? 38 TRP A O 1 ATOM 285 C CB . TRP A 1 42 ? -19.644 22.720 -61.369 1.00 31.13 ? 38 TRP A CB 1 ATOM 286 C CG . TRP A 1 42 ? -19.807 21.764 -62.501 1.00 41.87 ? 38 TRP A CG 1 ATOM 287 C CD1 . TRP A 1 42 ? -19.904 22.069 -63.826 1.00 46.61 ? 38 TRP A CD1 1 ATOM 288 C CD2 . TRP A 1 42 ? -19.918 20.340 -62.407 1.00 51.70 ? 38 TRP A CD2 1 ATOM 289 N NE1 . TRP A 1 42 ? -20.061 20.922 -64.565 1.00 55.56 ? 38 TRP A NE1 1 ATOM 290 C CE2 . TRP A 1 42 ? -20.073 19.846 -63.716 1.00 50.35 ? 38 TRP A CE2 1 ATOM 291 C CE3 . TRP A 1 42 ? -19.897 19.435 -61.343 1.00 39.92 ? 38 TRP A CE3 1 ATOM 292 C CZ2 . TRP A 1 42 ? -20.204 18.490 -63.989 1.00 38.81 ? 38 TRP A CZ2 1 ATOM 293 C CZ3 . TRP A 1 42 ? -20.028 18.092 -61.617 1.00 34.58 ? 38 TRP A CZ3 1 ATOM 294 C CH2 . TRP A 1 42 ? -20.179 17.631 -62.928 1.00 42.55 ? 38 TRP A CH2 1 ATOM 295 N N . ILE A 1 43 ? -20.722 23.085 -58.282 1.00 37.59 ? 39 ILE A N 1 ATOM 296 C CA . ILE A 1 43 ? -20.695 23.708 -56.970 1.00 42.51 ? 39 ILE A CA 1 ATOM 297 C C . ILE A 1 43 ? -19.975 22.808 -55.972 1.00 49.14 ? 39 ILE A C 1 ATOM 298 O O . ILE A 1 43 ? -19.794 21.616 -56.221 1.00 40.90 ? 39 ILE A O 1 ATOM 299 C CB . ILE A 1 43 ? -22.128 23.995 -56.462 1.00 38.47 ? 39 ILE A CB 1 ATOM 300 C CG1 . ILE A 1 43 ? -22.893 22.680 -56.283 1.00 46.85 ? 39 ILE A CG1 1 ATOM 301 C CG2 . ILE A 1 43 ? -22.875 24.918 -57.429 1.00 38.44 ? 39 ILE A CG2 1 ATOM 302 C CD1 . ILE A 1 43 ? -24.334 22.839 -55.842 1.00 43.03 ? 39 ILE A CD1 1 ATOM 303 N N . ARG A 1 44 ? -19.561 23.380 -54.847 1.00 39.73 ? 40 ARG A N 1 ATOM 304 C CA . ARG A 1 44 ? -19.050 22.585 -53.742 1.00 37.56 ? 40 ARG A CA 1 ATOM 305 C C . ARG A 1 44 ? -20.230 21.980 -52.991 1.00 52.66 ? 40 ARG A C 1 ATOM 306 O O . ARG A 1 44 ? -21.383 22.248 -53.327 1.00 64.87 ? 40 ARG A O 1 ATOM 307 C CB . ARG A 1 44 ? -18.194 23.436 -52.808 1.00 44.91 ? 40 ARG A CB 1 ATOM 308 C CG . ARG A 1 44 ? -16.948 24.001 -53.456 1.00 39.93 ? 40 ARG A CG 1 ATOM 309 C CD . ARG A 1 44 ? -16.142 24.800 -52.454 1.00 47.79 ? 40 ARG A CD 1 ATOM 310 N NE . ARG A 1 44 ? -15.006 25.482 -53.066 1.00 70.45 ? 40 ARG A NE 1 ATOM 311 C CZ . ARG A 1 44 ? -15.105 26.570 -53.823 1.00 81.03 ? 40 ARG A CZ 1 ATOM 312 N NH1 . ARG A 1 44 ? -16.293 27.098 -54.080 1.00 58.47 ? 40 ARG A NH1 1 ATOM 313 N NH2 . ARG A 1 44 ? -14.016 27.124 -54.332 1.00 93.36 ? 40 ARG A NH2 1 ATOM 314 N N . SER A 1 45 ? -19.946 21.179 -51.970 1.00 59.78 ? 41 SER A N 1 ATOM 315 C CA . SER A 1 45 ? -21.001 20.485 -51.239 1.00 70.39 ? 41 SER A CA 1 ATOM 316 C C . SER A 1 45 ? -21.885 21.458 -50.463 1.00 76.93 ? 41 SER A C 1 ATOM 317 O O . SER A 1 45 ? -23.074 21.202 -50.263 1.00 84.61 ? 41 SER A O 1 ATOM 318 C CB . SER A 1 45 ? -20.398 19.457 -50.282 1.00 62.54 ? 41 SER A CB 1 ATOM 319 O OG . SER A 1 45 ? -19.648 20.090 -49.262 1.00 68.09 ? 41 SER A OG 1 ATOM 320 N N . ASP A 1 46 ? -21.303 22.577 -50.040 1.00 69.87 ? 42 ASP A N 1 ATOM 321 C CA . ASP A 1 46 ? -22.034 23.573 -49.260 1.00 66.10 ? 42 ASP A CA 1 ATOM 322 C C . ASP A 1 46 ? -22.868 24.480 -50.164 1.00 55.10 ? 42 ASP A C 1 ATOM 323 O O . ASP A 1 46 ? -23.572 25.368 -49.681 1.00 52.03 ? 42 ASP A O 1 ATOM 324 C CB . ASP A 1 46 ? -21.070 24.407 -48.409 1.00 71.91 ? 42 ASP A CB 1 ATOM 325 C CG . ASP A 1 46 ? -19.952 25.024 -49.221 1.00 80.43 ? 42 ASP A CG 1 ATOM 326 O OD1 . ASP A 1 46 ? -19.508 24.384 -50.197 1.00 75.12 ? 42 ASP A OD1 1 ATOM 327 O OD2 . ASP A 1 46 ? -19.512 26.142 -48.880 1.00 72.95 ? 42 ASP A OD2 1 ATOM 328 N N . GLY A 1 47 ? -22.781 24.253 -51.472 1.00 58.98 ? 43 GLY A N 1 ATOM 329 C CA . GLY A 1 47 ? -23.678 24.886 -52.424 1.00 58.44 ? 43 GLY A CA 1 ATOM 330 C C . GLY A 1 47 ? -23.148 26.166 -53.042 1.00 59.75 ? 43 GLY A C 1 ATOM 331 O O . GLY A 1 47 ? -23.902 26.907 -53.675 1.00 64.05 ? 43 GLY A O 1 ATOM 332 N N . THR A 1 48 ? -21.856 26.424 -52.865 1.00 58.81 ? 44 THR A N 1 ATOM 333 C CA . THR A 1 48 ? -21.232 27.611 -53.439 1.00 43.50 ? 44 THR A CA 1 ATOM 334 C C . THR A 1 48 ? -20.653 27.279 -54.810 1.00 36.40 ? 44 THR A C 1 ATOM 335 O O . THR A 1 48 ? -20.032 26.232 -54.993 1.00 52.87 ? 44 THR A O 1 ATOM 336 C CB . THR A 1 48 ? -20.121 28.173 -52.527 1.00 43.64 ? 44 THR A CB 1 ATOM 337 O OG1 . THR A 1 48 ? -18.980 27.310 -52.563 1.00 58.68 ? 44 THR A OG1 1 ATOM 338 C CG2 . THR A 1 48 ? -20.618 28.309 -51.093 1.00 51.28 ? 44 THR A CG2 1 ATOM 339 N N . ALA A 1 49 ? -20.866 28.170 -55.773 1.00 35.02 ? 45 ALA A N 1 ATOM 340 C CA . ALA A 1 49 ? -20.391 27.949 -57.132 1.00 32.08 ? 45 ALA A CA 1 ATOM 341 C C . ALA A 1 49 ? -18.869 27.953 -57.170 1.00 43.22 ? 45 ALA A C 1 ATOM 342 O O . ALA A 1 49 ? -18.219 28.548 -56.309 1.00 62.52 ? 45 ALA A O 1 ATOM 343 C CB . ALA A 1 49 ? -20.953 29.006 -58.074 1.00 41.14 ? 45 ALA A CB 1 ATOM 344 N N . VAL A 1 50 ? -18.314 27.276 -58.170 1.00 39.91 ? 46 VAL A N 1 ATOM 345 C CA . VAL A 1 50 ? -16.871 27.182 -58.343 1.00 37.99 ? 46 VAL A CA 1 ATOM 346 C C . VAL A 1 50 ? -16.472 27.762 -59.693 1.00 42.31 ? 46 VAL A C 1 ATOM 347 O O . VAL A 1 50 ? -17.122 27.506 -60.708 1.00 44.55 ? 46 VAL A O 1 ATOM 348 C CB . VAL A 1 50 ? -16.385 25.721 -58.230 1.00 53.87 ? 46 VAL A CB 1 ATOM 349 C CG1 . VAL A 1 50 ? -16.607 25.211 -56.815 1.00 48.80 ? 46 VAL A CG1 1 ATOM 350 C CG2 . VAL A 1 50 ? -17.089 24.822 -59.249 1.00 43.43 ? 46 VAL A CG2 1 ATOM 351 N N . GLY A 1 51 ? -15.410 28.562 -59.689 1.00 53.36 ? 47 GLY A N 1 ATOM 352 C CA . GLY A 1 51 ? -14.913 29.193 -60.897 1.00 63.18 ? 47 GLY A CA 1 ATOM 353 C C . GLY A 1 51 ? -13.646 28.530 -61.389 1.00 54.45 ? 47 GLY A C 1 ATOM 354 O O . GLY A 1 51 ? -13.187 27.539 -60.820 1.00 54.04 ? 47 GLY A O 1 ATOM 355 N N . ASP A 1 52 ? -13.075 29.086 -62.451 1.00 53.00 ? 48 ASP A N 1 ATOM 356 C CA . ASP A 1 52 ? -11.857 28.547 -63.031 1.00 48.20 ? 48 ASP A CA 1 ATOM 357 C C . ASP A 1 52 ? -10.651 28.791 -62.136 1.00 51.92 ? 48 ASP A C 1 ATOM 358 O O . ASP A 1 52 ? -10.623 29.727 -61.337 1.00 55.29 ? 48 ASP A O 1 ATOM 359 C CB . ASP A 1 52 ? -11.600 29.163 -64.406 1.00 57.68 ? 48 ASP A CB 1 ATOM 360 C CG . ASP A 1 52 ? -12.743 28.933 -65.369 1.00 69.04 ? 48 ASP A CG 1 ATOM 361 O OD1 . ASP A 1 52 ? -13.912 29.052 -64.946 1.00 75.62 ? 48 ASP A OD1 1 ATOM 362 O OD2 . ASP A 1 52 ? -12.470 28.631 -66.550 1.00 71.25 ? 48 ASP A OD2 1 ATOM 363 N N . VAL A 1 53 ? -9.666 27.915 -62.277 1.00 49.17 ? 49 VAL A N 1 ATOM 364 C CA . VAL A 1 53 ? -8.356 28.091 -61.675 1.00 52.99 ? 49 VAL A CA 1 ATOM 365 C C . VAL A 1 53 ? -7.357 27.643 -62.733 1.00 58.70 ? 49 VAL A C 1 ATOM 366 O O . VAL A 1 53 ? -6.937 26.485 -62.726 1.00 63.85 ? 49 VAL A O 1 ATOM 367 C CB . VAL A 1 53 ? -8.187 27.277 -60.379 1.00 50.49 ? 49 VAL A CB 1 ATOM 368 C CG1 . VAL A 1 53 ? -6.842 27.590 -59.734 1.00 58.17 ? 49 VAL A CG1 1 ATOM 369 C CG2 . VAL A 1 53 ? -9.331 27.574 -59.414 1.00 62.66 ? 49 VAL A CG2 1 ATOM 370 N N . PRO A 1 54 ? -6.989 28.551 -63.659 1.00 71.54 ? 50 PRO A N 1 ATOM 371 C CA . PRO A 1 54 ? -6.311 28.127 -64.891 1.00 76.44 ? 50 PRO A CA 1 ATOM 372 C C . PRO A 1 54 ? -5.104 27.227 -64.635 1.00 62.00 ? 50 PRO A C 1 ATOM 373 O O . PRO A 1 54 ? -4.231 27.568 -63.835 1.00 52.55 ? 50 PRO A O 1 ATOM 374 C CB . PRO A 1 54 ? -5.878 29.454 -65.525 1.00 59.48 ? 50 PRO A CB 1 ATOM 375 C CG . PRO A 1 54 ? -6.857 30.458 -65.004 1.00 53.89 ? 50 PRO A CG 1 ATOM 376 C CD . PRO A 1 54 ? -7.167 30.015 -63.604 1.00 63.44 ? 50 PRO A CD 1 ATOM 377 N N . GLY A 1 55 ? -5.077 26.083 -65.315 1.00 47.35 ? 51 GLY A N 1 ATOM 378 C CA . GLY A 1 55 ? -4.034 25.091 -65.127 1.00 67.75 ? 51 GLY A CA 1 ATOM 379 C C . GLY A 1 55 ? -4.440 23.990 -64.159 1.00 52.46 ? 51 GLY A C 1 ATOM 380 O O . GLY A 1 55 ? -3.862 22.902 -64.178 1.00 42.89 ? 51 GLY A O 1 ATOM 381 N N . LEU A 1 56 ? -5.437 24.272 -63.321 1.00 39.97 ? 52 LEU A N 1 ATOM 382 C CA . LEU A 1 56 ? -5.928 23.306 -62.336 1.00 49.08 ? 52 LEU A CA 1 ATOM 383 C C . LEU A 1 56 ? -7.376 22.916 -62.598 1.00 43.56 ? 52 LEU A C 1 ATOM 384 O O . LEU A 1 56 ? -7.672 21.760 -62.892 1.00 43.36 ? 52 LEU A O 1 ATOM 385 C CB . LEU A 1 56 ? -5.813 23.866 -60.915 1.00 40.84 ? 52 LEU A CB 1 ATOM 386 C CG . LEU A 1 56 ? -4.419 24.173 -60.371 1.00 39.29 ? 52 LEU A CG 1 ATOM 387 C CD1 . LEU A 1 56 ? -4.505 24.433 -58.869 1.00 39.28 ? 52 LEU A CD1 1 ATOM 388 C CD2 . LEU A 1 56 ? -3.428 23.049 -60.678 1.00 44.92 ? 52 LEU A CD2 1 ATOM 389 N N . ARG A 1 57 ? -8.274 23.887 -62.465 1.00 48.08 ? 53 ARG A N 1 ATOM 390 C CA . ARG A 1 57 ? -9.700 23.652 -62.647 1.00 42.48 ? 53 ARG A CA 1 ATOM 391 C C . ARG A 1 57 ? -10.260 24.595 -63.696 1.00 56.07 ? 53 ARG A C 1 ATOM 392 O O . ARG A 1 57 ? -10.106 25.811 -63.593 1.00 70.43 ? 53 ARG A O 1 ATOM 393 C CB . ARG A 1 57 ? -10.447 23.835 -61.327 1.00 48.31 ? 53 ARG A CB 1 ATOM 394 C CG . ARG A 1 57 ? -11.949 23.657 -61.432 1.00 31.18 ? 53 ARG A CG 1 ATOM 395 C CD . ARG A 1 57 ? -12.580 23.638 -60.053 1.00 31.43 ? 53 ARG A CD 1 ATOM 396 N NE . ARG A 1 57 ? -12.434 24.924 -59.374 1.00 42.60 ? 53 ARG A NE 1 ATOM 397 C CZ . ARG A 1 57 ? -12.281 25.076 -58.061 1.00 48.47 ? 53 ARG A CZ 1 ATOM 398 N NH1 . ARG A 1 57 ? -12.247 24.025 -57.255 1.00 53.98 ? 53 ARG A NH1 1 ATOM 399 N NH2 . ARG A 1 57 ? -12.157 26.291 -57.548 1.00 63.23 ? 53 ARG A NH2 1 ATOM 400 N N . GLN A 1 58 ? -10.895 24.027 -64.713 1.00 58.18 ? 54 GLN A N 1 ATOM 401 C CA . GLN A 1 58 ? -11.517 24.820 -65.760 1.00 59.97 ? 54 GLN A CA 1 ATOM 402 C C . GLN A 1 58 ? -12.824 24.183 -66.209 1.00 58.33 ? 54 GLN A C 1 ATOM 403 O O . GLN A 1 58 ? -12.876 22.986 -66.484 1.00 52.11 ? 54 GLN A O 1 ATOM 404 C CB . GLN A 1 58 ? -10.565 24.975 -66.946 1.00 55.13 ? 54 GLN A CB 1 ATOM 405 C CG . GLN A 1 58 ? -9.261 25.680 -66.592 1.00 66.51 ? 54 GLN A CG 1 ATOM 406 C CD . GLN A 1 58 ? -8.367 25.936 -67.796 1.00 70.33 ? 54 GLN A CD 1 ATOM 407 O OE1 . GLN A 1 58 ? -7.507 26.817 -67.761 1.00 57.83 ? 54 GLN A OE1 1 ATOM 408 N NE2 . GLN A 1 58 ? -8.558 25.166 -68.863 1.00 78.64 ? 54 GLN A NE2 1 ATOM 409 N N . ILE A 1 59 ? -13.879 24.987 -66.277 1.00 64.07 ? 55 ILE A N 1 ATOM 410 C CA . ILE A 1 59 ? -15.149 24.522 -66.818 1.00 64.98 ? 55 ILE A CA 1 ATOM 411 C C . ILE A 1 59 ? -15.078 24.597 -68.338 1.00 72.41 ? 55 ILE A C 1 ATOM 412 O O . ILE A 1 59 ? -14.688 25.622 -68.899 1.00 80.46 ? 55 ILE A O 1 ATOM 413 C CB . ILE A 1 59 ? -16.335 25.352 -66.294 1.00 59.75 ? 55 ILE A CB 1 ATOM 414 C CG1 . ILE A 1 59 ? -16.399 25.258 -64.767 1.00 53.96 ? 55 ILE A CG1 1 ATOM 415 C CG2 . ILE A 1 59 ? -17.644 24.868 -66.919 1.00 60.13 ? 55 ILE A CG2 1 ATOM 416 C CD1 . ILE A 1 59 ? -17.395 26.201 -64.131 1.00 40.66 ? 55 ILE A CD1 1 ATOM 417 N N . SER A 1 60 ? -15.446 23.503 -68.998 1.00 71.93 ? 56 SER A N 1 ATOM 418 C CA . SER A 1 60 ? -15.275 23.385 -70.442 1.00 80.51 ? 56 SER A CA 1 ATOM 419 C C . SER A 1 60 ? -16.522 23.811 -71.213 1.00 73.33 ? 56 SER A C 1 ATOM 420 O O . SER A 1 60 ? -17.473 24.345 -70.639 1.00 69.69 ? 56 SER A O 1 ATOM 421 C CB . SER A 1 60 ? -14.900 21.950 -70.814 1.00 80.99 ? 56 SER A CB 1 ATOM 422 O OG . SER A 1 60 ? -16.037 21.111 -70.829 1.00 70.31 ? 56 SER A OG 1 ATOM 423 N N . SER A 1 61 ? -16.500 23.553 -72.519 1.00 65.55 ? 57 SER A N 1 ATOM 424 C CA . SER A 1 61 ? -17.524 24.032 -73.443 1.00 82.70 ? 57 SER A CA 1 ATOM 425 C C . SER A 1 61 ? -18.950 23.675 -73.025 1.00 88.33 ? 57 SER A C 1 ATOM 426 O O . SER A 1 61 ? -19.786 24.567 -72.872 1.00 95.26 ? 57 SER A O 1 ATOM 427 C CB . SER A 1 61 ? -17.246 23.478 -74.842 1.00 87.23 ? 57 SER A CB 1 ATOM 428 O OG . SER A 1 61 ? -16.011 23.961 -75.341 1.00 84.49 ? 57 SER A OG 1 ATOM 429 N N . ASP A 1 62 ? -19.229 22.386 -72.841 1.00 81.24 ? 58 ASP A N 1 ATOM 430 C CA . ASP A 1 62 ? -20.563 21.964 -72.426 1.00 81.45 ? 58 ASP A CA 1 ATOM 431 C C . ASP A 1 62 ? -20.555 21.361 -71.026 1.00 83.58 ? 58 ASP A C 1 ATOM 432 O O . ASP A 1 62 ? -20.185 20.202 -70.849 1.00 85.81 ? 58 ASP A O 1 ATOM 433 C CB . ASP A 1 62 ? -21.117 20.940 -73.425 1.00 100.07 ? 58 ASP A CB 1 ATOM 434 C CG . ASP A 1 62 ? -22.599 20.659 -73.228 1.00 119.07 ? 58 ASP A CG 1 ATOM 435 O OD1 . ASP A 1 62 ? -23.175 21.116 -72.220 1.00 124.14 ? 58 ASP A OD1 1 ATOM 436 O OD2 . ASP A 1 62 ? -23.188 19.971 -74.089 1.00 112.92 ? 58 ASP A OD2 1 ATOM 437 N N . GLY A 1 63 ? -20.993 22.152 -70.047 1.00 87.48 ? 59 GLY A N 1 ATOM 438 C CA . GLY A 1 63 ? -21.384 21.666 -68.732 1.00 81.26 ? 59 GLY A CA 1 ATOM 439 C C . GLY A 1 63 ? -20.480 20.620 -68.107 1.00 75.59 ? 59 GLY A C 1 ATOM 440 O O . GLY A 1 63 ? -20.974 19.719 -67.427 1.00 68.67 ? 59 GLY A O 1 ATOM 441 N N . LYS A 1 64 ? -19.170 20.732 -68.318 1.00 77.47 ? 60 LYS A N 1 ATOM 442 C CA . LYS A 1 64 ? -18.247 19.667 -67.926 1.00 56.81 ? 60 LYS A CA 1 ATOM 443 C C . LYS A 1 64 ? -17.059 20.201 -67.137 1.00 45.21 ? 60 LYS A C 1 ATOM 444 O O . LYS A 1 64 ? -16.266 20.997 -67.640 1.00 61.92 ? 60 LYS A O 1 ATOM 445 C CB . LYS A 1 64 ? -17.757 18.915 -69.165 1.00 49.94 ? 60 LYS A CB 1 ATOM 446 C CG . LYS A 1 64 ? -17.447 17.451 -68.942 1.00 46.18 ? 60 LYS A CG 1 ATOM 447 C CD . LYS A 1 64 ? -17.378 16.729 -70.274 1.00 52.48 ? 60 LYS A CD 1 ATOM 448 C CE . LYS A 1 64 ? -16.551 15.462 -70.190 1.00 72.68 ? 60 LYS A CE 1 ATOM 449 N NZ . LYS A 1 64 ? -17.113 14.489 -69.218 1.00 83.21 ? 60 LYS A NZ 1 ATOM 450 N N . LEU A 1 65 ? -16.945 19.747 -65.893 1.00 35.32 ? 61 LEU A N 1 ATOM 451 C CA . LEU A 1 65 ? -15.857 20.158 -65.017 1.00 35.13 ? 61 LEU A CA 1 ATOM 452 C C . LEU A 1 65 ? -14.585 19.389 -65.361 1.00 35.90 ? 61 LEU A C 1 ATOM 453 O O . LEU A 1 65 ? -14.583 18.158 -65.366 1.00 32.41 ? 61 LEU A O 1 ATOM 454 C CB . LEU A 1 65 ? -16.238 19.934 -63.554 1.00 31.34 ? 61 LEU A CB 1 ATOM 455 C CG . LEU A 1 65 ? -15.264 20.472 -62.506 1.00 31.09 ? 61 LEU A CG 1 ATOM 456 C CD1 . LEU A 1 65 ? -15.145 21.993 -62.593 1.00 46.45 ? 61 LEU A CD1 1 ATOM 457 C CD2 . LEU A 1 65 ? -15.706 20.038 -61.117 1.00 31.73 ? 61 LEU A CD2 1 ATOM 458 N N . VAL A 1 66 ? -13.508 20.119 -65.643 1.00 53.27 ? 62 VAL A N 1 ATOM 459 C CA . VAL A 1 66 ? -12.253 19.511 -66.083 1.00 45.81 ? 62 VAL A CA 1 ATOM 460 C C . VAL A 1 66 ? -11.122 19.775 -65.093 1.00 33.80 ? 62 VAL A C 1 ATOM 461 O O . VAL A 1 66 ? -11.021 20.858 -64.516 1.00 43.14 ? 62 VAL A O 1 ATOM 462 C CB . VAL A 1 66 ? -11.840 20.031 -67.483 1.00 38.98 ? 62 VAL A CB 1 ATOM 463 C CG1 . VAL A 1 66 ? -10.473 19.476 -67.898 1.00 35.05 ? 62 VAL A CG1 1 ATOM 464 C CG2 . VAL A 1 66 ? -12.905 19.666 -68.512 1.00 39.47 ? 62 VAL A CG2 1 ATOM 465 N N . PHE A 1 67 ? -10.285 18.760 -64.900 1.00 35.16 ? 63 PHE A N 1 ATOM 466 C CA . PHE A 1 67 ? -9.079 18.871 -64.089 1.00 46.63 ? 63 PHE A CA 1 ATOM 467 C C . PHE A 1 67 ? -7.877 18.426 -64.913 1.00 53.42 ? 63 PHE A C 1 ATOM 468 O O . PHE A 1 67 ? -7.489 17.259 -64.860 1.00 55.58 ? 63 PHE A O 1 ATOM 469 C CB . PHE A 1 67 ? -9.191 18.024 -62.819 1.00 41.23 ? 63 PHE A CB 1 ATOM 470 C CG . PHE A 1 67 ? -10.250 18.497 -61.866 1.00 29.69 ? 63 PHE A CG 1 ATOM 471 C CD1 . PHE A 1 67 ? -11.575 18.159 -62.059 1.00 31.66 ? 63 PHE A CD1 1 ATOM 472 C CD2 . PHE A 1 67 ? -9.919 19.279 -60.774 1.00 37.35 ? 63 PHE A CD2 1 ATOM 473 C CE1 . PHE A 1 67 ? -12.549 18.593 -61.185 1.00 42.27 ? 63 PHE A CE1 1 ATOM 474 C CE2 . PHE A 1 67 ? -10.890 19.715 -59.897 1.00 36.39 ? 63 PHE A CE2 1 ATOM 475 C CZ . PHE A 1 67 ? -12.205 19.372 -60.103 1.00 45.65 ? 63 PHE A CZ 1 ATOM 476 N N . PRO A 1 68 ? -7.284 19.349 -65.689 1.00 50.67 ? 64 PRO A N 1 ATOM 477 C CA . PRO A 1 68 ? -6.162 18.919 -66.528 1.00 40.25 ? 64 PRO A CA 1 ATOM 478 C C . PRO A 1 68 ? -4.972 18.472 -65.683 1.00 33.72 ? 64 PRO A C 1 ATOM 479 O O . PRO A 1 68 ? -4.923 18.795 -64.495 1.00 40.08 ? 64 PRO A O 1 ATOM 480 C CB . PRO A 1 68 ? -5.824 20.174 -67.343 1.00 39.29 ? 64 PRO A CB 1 ATOM 481 C CG . PRO A 1 68 ? -7.034 21.075 -67.217 1.00 27.46 ? 64 PRO A CG 1 ATOM 482 C CD . PRO A 1 68 ? -7.580 20.782 -65.859 1.00 33.70 ? 64 PRO A CD 1 ATOM 483 N N . PRO A 1 69 ? -4.031 17.726 -66.280 1.00 28.65 ? 65 PRO A N 1 ATOM 484 C CA . PRO A 1 69 ? -2.839 17.288 -65.544 1.00 40.09 ? 65 PRO A CA 1 ATOM 485 C C . PRO A 1 69 ? -2.034 18.469 -65.021 1.00 43.06 ? 65 PRO A C 1 ATOM 486 O O . PRO A 1 69 ? -2.162 19.571 -65.556 1.00 55.77 ? 65 PRO A O 1 ATOM 487 C CB . PRO A 1 69 ? -2.044 16.494 -66.587 1.00 40.04 ? 65 PRO A CB 1 ATOM 488 C CG . PRO A 1 69 ? -2.583 16.936 -67.919 1.00 43.18 ? 65 PRO A CG 1 ATOM 489 C CD . PRO A 1 69 ? -4.020 17.270 -67.680 1.00 32.10 ? 65 PRO A CD 1 ATOM 490 N N . PHE A 1 70 ? -1.222 18.245 -63.993 1.00 36.05 ? 66 PHE A N 1 ATOM 491 C CA . PHE A 1 70 ? -0.530 19.343 -63.333 1.00 48.00 ? 66 PHE A CA 1 ATOM 492 C C . PHE A 1 70 ? 0.754 18.895 -62.651 1.00 55.28 ? 66 PHE A C 1 ATOM 493 O O . PHE A 1 70 ? 0.926 17.720 -62.328 1.00 45.62 ? 66 PHE A O 1 ATOM 494 C CB . PHE A 1 70 ? -1.457 19.998 -62.307 1.00 38.42 ? 66 PHE A CB 1 ATOM 495 C CG . PHE A 1 70 ? -1.970 19.048 -61.253 1.00 34.40 ? 66 PHE A CG 1 ATOM 496 C CD1 . PHE A 1 70 ? -2.965 18.133 -61.548 1.00 43.07 ? 66 PHE A CD1 1 ATOM 497 C CD2 . PHE A 1 70 ? -1.463 19.077 -59.966 1.00 43.27 ? 66 PHE A CD2 1 ATOM 498 C CE1 . PHE A 1 70 ? -3.437 17.262 -60.578 1.00 45.30 ? 66 PHE A CE1 1 ATOM 499 C CE2 . PHE A 1 70 ? -1.932 18.208 -58.996 1.00 38.38 ? 66 PHE A CE2 1 ATOM 500 C CZ . PHE A 1 70 ? -2.918 17.302 -59.304 1.00 35.54 ? 66 PHE A CZ 1 ATOM 501 N N . ARG A 1 71 ? 1.655 19.850 -62.445 1.00 54.77 ? 67 ARG A N 1 ATOM 502 C CA . ARG A 1 71 ? 2.863 19.614 -61.671 1.00 53.50 ? 67 ARG A CA 1 ATOM 503 C C . ARG A 1 71 ? 2.504 19.233 -60.244 1.00 48.48 ? 67 ARG A C 1 ATOM 504 O O . ARG A 1 71 ? 1.502 19.697 -59.705 1.00 43.01 ? 67 ARG A O 1 ATOM 505 C CB . ARG A 1 71 ? 3.755 20.858 -61.665 1.00 64.09 ? 67 ARG A CB 1 ATOM 506 C CG . ARG A 1 71 ? 4.915 20.814 -62.638 1.00 65.06 ? 67 ARG A CG 1 ATOM 507 C CD . ARG A 1 71 ? 6.213 21.178 -61.944 1.00 79.28 ? 67 ARG A CD 1 ATOM 508 N NE . ARG A 1 71 ? 7.285 21.465 -62.895 1.00 88.13 ? 67 ARG A NE 1 ATOM 509 C CZ . ARG A 1 71 ? 8.538 21.028 -62.789 1.00 89.71 ? 67 ARG A CZ 1 ATOM 510 N NH1 . ARG A 1 71 ? 8.916 20.266 -61.769 1.00 89.91 ? 67 ARG A NH1 1 ATOM 511 N NH2 . ARG A 1 71 ? 9.424 21.358 -63.718 1.00 81.20 ? 67 ARG A NH2 1 ATOM 512 N N . ALA A 1 72 ? 3.325 18.386 -59.635 1.00 62.93 ? 68 ALA A N 1 ATOM 513 C CA . ALA A 1 72 ? 3.159 18.053 -58.228 1.00 60.34 ? 68 ALA A CA 1 ATOM 514 C C . ALA A 1 72 ? 3.252 19.325 -57.389 1.00 55.68 ? 68 ALA A C 1 ATOM 515 O O . ALA A 1 72 ? 2.669 19.419 -56.308 1.00 49.71 ? 68 ALA A O 1 ATOM 516 C CB . ALA A 1 72 ? 4.208 17.042 -57.796 1.00 50.23 ? 68 ALA A CB 1 ATOM 517 N N . GLU A 1 73 ? 3.981 20.305 -57.916 1.00 64.89 ? 69 GLU A N 1 ATOM 518 C CA . GLU A 1 73 ? 4.171 21.591 -57.254 1.00 68.11 ? 69 GLU A CA 1 ATOM 519 C C . GLU A 1 73 ? 2.926 22.470 -57.364 1.00 56.99 ? 69 GLU A C 1 ATOM 520 O O . GLU A 1 73 ? 2.682 23.325 -56.510 1.00 51.51 ? 69 GLU A O 1 ATOM 521 C CB . GLU A 1 73 ? 5.380 22.320 -57.852 1.00 60.65 ? 69 GLU A CB 1 ATOM 522 C CG . GLU A 1 73 ? 6.731 21.723 -57.470 1.00 71.09 ? 69 GLU A CG 1 ATOM 523 C CD . GLU A 1 73 ? 6.935 20.317 -58.004 1.00 72.17 ? 69 GLU A CD 1 ATOM 524 O OE1 . GLU A 1 73 ? 6.149 19.888 -58.875 1.00 74.43 ? 69 GLU A OE1 1 ATOM 525 O OE2 . GLU A 1 73 ? 7.880 19.638 -57.550 1.00 66.95 ? 69 GLU A OE2 1 ATOM 526 N N . ASP A 1 74 ? 2.140 22.250 -58.414 1.00 60.59 ? 70 ASP A N 1 ATOM 527 C CA . ASP A 1 74 ? 0.942 23.047 -58.665 1.00 59.72 ? 70 ASP A CA 1 ATOM 528 C C . ASP A 1 74 ? -0.273 22.467 -57.950 1.00 50.26 ? 70 ASP A C 1 ATOM 529 O O . ASP A 1 74 ? -1.385 22.979 -58.087 1.00 54.09 ? 70 ASP A O 1 ATOM 530 C CB . ASP A 1 74 ? 0.664 23.136 -60.168 1.00 55.61 ? 70 ASP A CB 1 ATOM 531 C CG . ASP A 1 74 ? 1.703 23.956 -60.909 1.00 55.89 ? 70 ASP A CG 1 ATOM 532 O OD1 . ASP A 1 74 ? 2.420 24.748 -60.261 1.00 43.91 ? 70 ASP A OD1 1 ATOM 533 O OD2 . ASP A 1 74 ? 1.797 23.813 -62.147 1.00 62.06 ? 70 ASP A OD2 1 ATOM 534 N N . TYR A 1 75 ? -0.058 21.396 -57.193 1.00 56.24 ? 71 TYR A N 1 ATOM 535 C CA . TYR A 1 75 ? -1.133 20.776 -56.431 1.00 45.91 ? 71 TYR A CA 1 ATOM 536 C C . TYR A 1 75 ? -1.741 21.785 -55.467 1.00 45.80 ? 71 TYR A C 1 ATOM 537 O O . TYR A 1 75 ? -1.030 22.424 -54.691 1.00 48.81 ? 71 TYR A O 1 ATOM 538 C CB . TYR A 1 75 ? -0.623 19.554 -55.663 1.00 43.27 ? 71 TYR A CB 1 ATOM 539 C CG . TYR A 1 75 ? -1.678 18.887 -54.801 1.00 40.89 ? 71 TYR A CG 1 ATOM 540 C CD1 . TYR A 1 75 ? -1.952 19.347 -53.520 1.00 41.11 ? 71 TYR A CD1 1 ATOM 541 C CD2 . TYR A 1 75 ? -2.399 17.798 -55.269 1.00 43.52 ? 71 TYR A CD2 1 ATOM 542 C CE1 . TYR A 1 75 ? -2.915 18.744 -52.732 1.00 42.57 ? 71 TYR A CE1 1 ATOM 543 C CE2 . TYR A 1 75 ? -3.364 17.188 -54.485 1.00 35.43 ? 71 TYR A CE2 1 ATOM 544 C CZ . TYR A 1 75 ? -3.616 17.666 -53.219 1.00 42.21 ? 71 TYR A CZ 1 ATOM 545 O OH . TYR A 1 75 ? -4.573 17.062 -52.436 1.00 37.59 ? 71 TYR A OH 1 ATOM 546 N N . ARG A 1 76 ? -3.061 21.922 -55.532 1.00 46.53 ? 72 ARG A N 1 ATOM 547 C CA . ARG A 1 76 ? -3.793 22.808 -54.639 1.00 52.04 ? 72 ARG A CA 1 ATOM 548 C C . ARG A 1 76 ? -4.956 22.034 -54.029 1.00 51.89 ? 72 ARG A C 1 ATOM 549 O O . ARG A 1 76 ? -5.764 21.439 -54.743 1.00 49.87 ? 72 ARG A O 1 ATOM 550 C CB . ARG A 1 76 ? -4.281 24.053 -55.385 1.00 45.36 ? 72 ARG A CB 1 ATOM 551 C CG . ARG A 1 76 ? -4.672 25.198 -54.466 1.00 53.49 ? 72 ARG A CG 1 ATOM 552 C CD . ARG A 1 76 ? -3.457 25.804 -53.766 1.00 51.85 ? 72 ARG A CD 1 ATOM 553 N NE . ARG A 1 76 ? -3.774 26.245 -52.410 1.00 63.34 ? 72 ARG A NE 1 ATOM 554 C CZ . ARG A 1 76 ? -2.868 26.567 -51.492 1.00 65.08 ? 72 ARG A CZ 1 ATOM 555 N NH1 . ARG A 1 76 ? -1.573 26.501 -51.770 1.00 64.98 ? 72 ARG A NH1 1 ATOM 556 N NH2 . ARG A 1 76 ? -3.262 26.955 -50.289 1.00 68.82 ? 72 ARG A NH2 1 ATOM 557 N N . GLN A 1 77 ? -5.019 22.040 -52.702 1.00 48.76 ? 73 GLN A N 1 ATOM 558 C CA . GLN A 1 77 ? -5.945 21.187 -51.963 1.00 46.38 ? 73 GLN A CA 1 ATOM 559 C C . GLN A 1 77 ? -7.408 21.455 -52.301 1.00 44.50 ? 73 GLN A C 1 ATOM 560 O O . GLN A 1 77 ? -8.138 20.541 -52.686 1.00 48.96 ? 73 GLN A O 1 ATOM 561 C CB . GLN A 1 77 ? -5.728 21.364 -50.459 1.00 50.34 ? 73 GLN A CB 1 ATOM 562 C CG . GLN A 1 77 ? -6.664 20.527 -49.595 1.00 47.56 ? 73 GLN A CG 1 ATOM 563 C CD . GLN A 1 77 ? -6.219 20.454 -48.143 1.00 47.61 ? 73 GLN A CD 1 ATOM 564 O OE1 . GLN A 1 77 ? -5.042 20.629 -47.830 1.00 57.16 ? 73 GLN A OE1 1 ATOM 565 N NE2 . GLN A 1 77 ? -7.163 20.191 -47.248 1.00 46.69 ? 73 GLN A NE2 1 ATOM 566 N N . GLU A 1 78 ? -7.831 22.707 -52.157 1.00 52.48 ? 74 GLU A N 1 ATOM 567 C CA . GLU A 1 78 ? -9.240 23.062 -52.299 1.00 57.78 ? 74 GLU A CA 1 ATOM 568 C C . GLU A 1 78 ? -9.777 22.753 -53.698 1.00 59.05 ? 74 GLU A C 1 ATOM 569 O O . GLU A 1 78 ? -10.984 22.601 -53.882 1.00 66.12 ? 74 GLU A O 1 ATOM 570 C CB . GLU A 1 78 ? -9.456 24.545 -51.968 1.00 60.83 ? 74 GLU A CB 1 ATOM 571 C CG . GLU A 1 78 ? -8.668 25.526 -52.825 1.00 87.76 ? 74 GLU A CG 1 ATOM 572 C CD . GLU A 1 78 ? -7.273 25.807 -52.296 1.00 80.54 ? 74 GLU A CD 1 ATOM 573 O OE1 . GLU A 1 78 ? -6.790 25.047 -51.429 1.00 68.10 ? 74 GLU A OE1 1 ATOM 574 O OE2 . GLU A 1 78 ? -6.656 26.796 -52.748 1.00 85.57 ? 74 GLU A OE2 1 ATOM 575 N N . VAL A 1 79 ? -8.884 22.681 -54.681 1.00 40.85 ? 75 VAL A N 1 ATOM 576 C CA . VAL A 1 79 ? -9.265 22.272 -56.032 1.00 41.71 ? 75 VAL A CA 1 ATOM 577 C C . VAL A 1 79 ? -9.385 20.755 -56.159 1.00 46.69 ? 75 VAL A C 1 ATOM 578 O O . VAL A 1 79 ? -10.369 20.238 -56.689 1.00 54.83 ? 75 VAL A O 1 ATOM 579 C CB . VAL A 1 79 ? -8.245 22.761 -57.081 1.00 42.95 ? 75 VAL A CB 1 ATOM 580 C CG1 . VAL A 1 79 ? -8.632 22.269 -58.483 1.00 33.06 ? 75 VAL A CG1 1 ATOM 581 C CG2 . VAL A 1 79 ? -8.133 24.280 -57.047 1.00 51.96 ? 75 VAL A CG2 1 ATOM 582 N N . HIS A 1 80 ? -8.375 20.053 -55.656 1.00 50.33 ? 76 HIS A N 1 ATOM 583 C CA . HIS A 1 80 ? -8.187 18.633 -55.939 1.00 49.72 ? 76 HIS A CA 1 ATOM 584 C C . HIS A 1 80 ? -8.854 17.754 -54.893 1.00 53.23 ? 76 HIS A C 1 ATOM 585 O O . HIS A 1 80 ? -9.755 16.981 -55.218 1.00 55.47 ? 76 HIS A O 1 ATOM 586 C CB . HIS A 1 80 ? -6.698 18.319 -56.038 1.00 46.57 ? 76 HIS A CB 1 ATOM 587 C CG . HIS A 1 80 ? -6.017 19.015 -57.174 1.00 36.79 ? 76 HIS A CG 1 ATOM 588 N ND1 . HIS A 1 80 ? -5.291 20.174 -57.009 1.00 35.18 ? 76 HIS A ND1 1 ATOM 589 C CD2 . HIS A 1 80 ? -5.971 18.727 -58.497 1.00 35.04 ? 76 HIS A CD2 1 ATOM 590 C CE1 . HIS A 1 80 ? -4.817 20.564 -58.179 1.00 49.47 ? 76 HIS A CE1 1 ATOM 591 N NE2 . HIS A 1 80 ? -5.216 19.704 -59.099 1.00 34.58 ? 76 HIS A NE2 1 ATOM 592 N N . ALA A 1 81 ? -8.425 17.877 -53.640 1.00 41.00 ? 77 ALA A N 1 ATOM 593 C CA . ALA A 1 81 ? -9.053 17.115 -52.572 1.00 45.19 ? 77 ALA A CA 1 ATOM 594 C C . ALA A 1 81 ? -10.200 17.963 -52.054 1.00 55.05 ? 77 ALA A C 1 ATOM 595 O O . ALA A 1 81 ? -9.998 18.960 -51.362 1.00 64.24 ? 77 ALA A O 1 ATOM 596 C CB . ALA A 1 81 ? -8.058 16.796 -51.466 1.00 43.54 ? 77 ALA A CB 1 ATOM 597 N N . GLN A 1 82 ? -11.413 17.541 -52.391 1.00 55.53 ? 78 GLN A N 1 ATOM 598 C CA . GLN A 1 82 ? -12.579 18.400 -52.258 1.00 51.46 ? 78 GLN A CA 1 ATOM 599 C C . GLN A 1 82 ? -13.871 17.591 -52.279 1.00 47.41 ? 78 GLN A C 1 ATOM 600 O O . GLN A 1 82 ? -13.891 16.446 -52.731 1.00 53.41 ? 78 GLN A O 1 ATOM 601 C CB . GLN A 1 82 ? -12.578 19.441 -53.384 1.00 53.46 ? 78 GLN A CB 1 ATOM 602 C CG . GLN A 1 82 ? -13.717 20.456 -53.347 1.00 53.12 ? 78 GLN A CG 1 ATOM 603 C CD . GLN A 1 82 ? -13.686 21.324 -52.105 1.00 52.30 ? 78 GLN A CD 1 ATOM 604 O OE1 . GLN A 1 82 ? -14.523 21.185 -51.214 1.00 47.97 ? 78 GLN A OE1 1 ATOM 605 N NE2 . GLN A 1 82 ? -12.723 22.233 -52.047 1.00 56.67 ? 78 GLN A NE2 1 ATOM 606 N N . VAL A 1 83 ? -14.944 18.200 -51.786 1.00 52.87 ? 79 VAL A N 1 ATOM 607 C CA . VAL A 1 83 ? -16.287 17.663 -51.952 1.00 39.23 ? 79 VAL A CA 1 ATOM 608 C C . VAL A 1 83 ? -17.023 18.522 -52.977 1.00 44.88 ? 79 VAL A C 1 ATOM 609 O O . VAL A 1 83 ? -17.084 19.745 -52.840 1.00 51.04 ? 79 VAL A O 1 ATOM 610 C CB . VAL A 1 83 ? -17.068 17.642 -50.627 1.00 41.30 ? 79 VAL A CB 1 ATOM 611 C CG1 . VAL A 1 83 ? -18.212 16.642 -50.715 1.00 37.64 ? 79 VAL A CG1 1 ATOM 612 C CG2 . VAL A 1 83 ? -16.138 17.306 -49.460 1.00 52.89 ? 79 VAL A CG2 1 ATOM 613 N N . TYR A 1 84 ? -17.573 17.879 -54.004 1.00 41.55 ? 80 TYR A N 1 ATOM 614 C CA . TYR A 1 84 ? -18.237 18.589 -55.095 1.00 44.00 ? 80 TYR A CA 1 ATOM 615 C C . TYR A 1 84 ? -19.698 18.188 -55.238 1.00 39.26 ? 80 TYR A C 1 ATOM 616 O O . TYR A 1 84 ? -20.209 17.355 -54.490 1.00 37.70 ? 80 TYR A O 1 ATOM 617 C CB . TYR A 1 84 ? -17.506 18.339 -56.418 1.00 38.43 ? 80 TYR A CB 1 ATOM 618 C CG . TYR A 1 84 ? -16.287 19.210 -56.611 1.00 37.46 ? 80 TYR A CG 1 ATOM 619 C CD1 . TYR A 1 84 ? -16.399 20.498 -57.113 1.00 36.66 ? 80 TYR A CD1 1 ATOM 620 C CD2 . TYR A 1 84 ? -15.024 18.745 -56.290 1.00 63.50 ? 80 TYR A CD2 1 ATOM 621 C CE1 . TYR A 1 84 ? -15.283 21.296 -57.288 1.00 40.36 ? 80 TYR A CE1 1 ATOM 622 C CE2 . TYR A 1 84 ? -13.906 19.534 -56.465 1.00 52.54 ? 80 TYR A CE2 1 ATOM 623 C CZ . TYR A 1 84 ? -14.039 20.808 -56.961 1.00 46.52 ? 80 TYR A CZ 1 ATOM 624 O OH . TYR A 1 84 ? -12.923 21.593 -57.132 1.00 54.11 ? 80 TYR A OH 1 ATOM 625 N N . ALA A 1 85 ? -20.362 18.801 -56.211 1.00 42.58 ? 81 ALA A N 1 ATOM 626 C CA . ALA A 1 85 ? -21.747 18.489 -56.516 1.00 47.49 ? 81 ALA A CA 1 ATOM 627 C C . ALA A 1 85 ? -22.111 19.025 -57.894 1.00 38.95 ? 81 ALA A C 1 ATOM 628 O O . ALA A 1 85 ? -21.290 19.647 -58.570 1.00 41.38 ? 81 ALA A O 1 ATOM 629 C CB . ALA A 1 85 ? -22.671 19.067 -55.456 1.00 39.03 ? 81 ALA A CB 1 ATOM 630 N N . CYS A 1 86 ? -23.351 18.775 -58.297 1.00 34.36 ? 82 CYS A N 1 ATOM 631 C CA . CYS A 1 86 ? -23.841 19.165 -59.611 1.00 29.15 ? 82 CYS A CA 1 ATOM 632 C C . CYS A 1 86 ? -25.262 19.698 -59.476 1.00 41.52 ? 82 CYS A C 1 ATOM 633 O O . CYS A 1 86 ? -26.116 19.046 -58.874 1.00 51.27 ? 82 CYS A O 1 ATOM 634 C CB . CYS A 1 86 ? -23.796 17.977 -60.571 1.00 40.61 ? 82 CYS A CB 1 ATOM 635 S SG . CYS A 1 86 ? -24.400 18.342 -62.227 1.00 68.35 ? 82 CYS A SG 1 ATOM 636 N N . LEU A 1 87 ? -25.510 20.880 -60.035 1.00 41.15 ? 83 LEU A N 1 ATOM 637 C CA . LEU A 1 87 ? -26.795 21.555 -59.868 1.00 48.22 ? 83 LEU A CA 1 ATOM 638 C C . LEU A 1 87 ? -27.518 21.735 -61.200 1.00 54.19 ? 83 LEU A C 1 ATOM 639 O O . LEU A 1 87 ? -27.062 22.476 -62.070 1.00 59.22 ? 83 LEU A O 1 ATOM 640 C CB . LEU A 1 87 ? -26.595 22.917 -59.193 1.00 48.09 ? 83 LEU A CB 1 ATOM 641 C CG . LEU A 1 87 ? -27.852 23.597 -58.640 1.00 35.24 ? 83 LEU A CG 1 ATOM 642 C CD1 . LEU A 1 87 ? -27.493 24.511 -57.474 1.00 26.25 ? 83 LEU A CD1 1 ATOM 643 C CD2 . LEU A 1 87 ? -28.589 24.383 -59.722 1.00 43.99 ? 83 LEU A CD2 1 ATOM 644 N N . ALA A 1 88 ? -28.651 21.053 -61.342 1.00 45.85 ? 84 ALA A N 1 ATOM 645 C CA . ALA A 1 88 ? -29.526 21.223 -62.496 1.00 47.86 ? 84 ALA A CA 1 ATOM 646 C C . ALA A 1 88 ? -30.689 22.118 -62.091 1.00 51.26 ? 84 ALA A C 1 ATOM 647 O O . ALA A 1 88 ? -31.291 21.915 -61.035 1.00 47.71 ? 84 ALA A O 1 ATOM 648 C CB . ALA A 1 88 ? -30.027 19.878 -63.002 1.00 52.41 ? 84 ALA A CB 1 ATOM 649 N N . ARG A 1 89 ? -31.002 23.107 -62.922 1.00 56.09 ? 85 ARG A N 1 ATOM 650 C CA . ARG A 1 89 ? -31.988 24.115 -62.549 1.00 59.74 ? 85 ARG A CA 1 ATOM 651 C C . ARG A 1 89 ? -32.756 24.689 -63.733 1.00 61.07 ? 85 ARG A C 1 ATOM 652 O O . ARG A 1 89 ? -32.201 24.904 -64.810 1.00 52.83 ? 85 ARG A O 1 ATOM 653 C CB . ARG A 1 89 ? -31.297 25.252 -61.797 1.00 48.74 ? 85 ARG A CB 1 ATOM 654 C CG . ARG A 1 89 ? -32.219 26.371 -61.364 1.00 56.09 ? 85 ARG A CG 1 ATOM 655 C CD . ARG A 1 89 ? -31.477 27.363 -60.497 1.00 48.57 ? 85 ARG A CD 1 ATOM 656 N NE . ARG A 1 89 ? -30.453 28.077 -61.252 1.00 61.10 ? 85 ARG A NE 1 ATOM 657 C CZ . ARG A 1 89 ? -29.518 28.843 -60.702 1.00 57.61 ? 85 ARG A CZ 1 ATOM 658 N NH1 . ARG A 1 89 ? -29.470 28.995 -59.386 1.00 54.51 ? 85 ARG A NH1 1 ATOM 659 N NH2 . ARG A 1 89 ? -28.627 29.455 -61.468 1.00 58.79 ? 85 ARG A NH2 1 ATOM 660 N N . ASN A 1 90 ? -34.039 24.946 -63.501 1.00 49.45 ? 86 ASN A N 1 ATOM 661 C CA . ASN A 1 90 ? -34.883 25.657 -64.451 1.00 50.99 ? 86 ASN A CA 1 ATOM 662 C C . ASN A 1 90 ? -36.014 26.357 -63.690 1.00 59.91 ? 86 ASN A C 1 ATOM 663 O O . ASN A 1 90 ? -35.953 26.481 -62.466 1.00 60.17 ? 86 ASN A O 1 ATOM 664 C CB . ASN A 1 90 ? -35.425 24.711 -65.531 1.00 55.29 ? 86 ASN A CB 1 ATOM 665 C CG . ASN A 1 90 ? -36.268 23.586 -64.967 1.00 61.63 ? 86 ASN A CG 1 ATOM 666 O OD1 . ASN A 1 90 ? -36.542 23.538 -63.770 1.00 67.36 ? 86 ASN A OD1 1 ATOM 667 N ND2 . ASN A 1 90 ? -36.692 22.672 -65.837 1.00 47.16 ? 86 ASN A ND2 1 ATOM 668 N N . GLN A 1 91 ? -37.028 26.809 -64.423 1.00 61.06 ? 87 GLN A N 1 ATOM 669 C CA . GLN A 1 91 ? -38.095 27.660 -63.889 1.00 50.89 ? 87 GLN A CA 1 ATOM 670 C C . GLN A 1 91 ? -38.662 27.205 -62.544 1.00 54.74 ? 87 GLN A C 1 ATOM 671 O O . GLN A 1 91 ? -38.949 28.024 -61.670 1.00 64.42 ? 87 GLN A O 1 ATOM 672 C CB . GLN A 1 91 ? -39.252 27.721 -64.888 1.00 53.49 ? 87 GLN A CB 1 ATOM 673 C CG . GLN A 1 91 ? -38.887 28.201 -66.285 1.00 66.42 ? 87 GLN A CG 1 ATOM 674 C CD . GLN A 1 91 ? -40.044 28.107 -67.274 1.00 61.80 ? 87 GLN A CD 1 ATOM 675 O OE1 . GLN A 1 91 ? -39.892 28.457 -68.444 1.00 64.79 ? 87 GLN A OE1 1 ATOM 676 N NE2 . GLN A 1 91 ? -41.202 27.636 -66.813 1.00 68.02 ? 87 GLN A NE2 1 ATOM 677 N N . PHE A 1 92 ? -38.814 25.895 -62.389 1.00 42.91 ? 88 PHE A N 1 ATOM 678 C CA . PHE A 1 92 ? -39.587 25.321 -61.292 1.00 50.97 ? 88 PHE A CA 1 ATOM 679 C C . PHE A 1 92 ? -38.814 25.338 -59.982 1.00 57.80 ? 88 PHE A C 1 ATOM 680 O O . PHE A 1 92 ? -39.226 25.978 -59.014 1.00 73.42 ? 88 PHE A O 1 ATOM 681 C CB . PHE A 1 92 ? -40.003 23.894 -61.646 1.00 56.66 ? 88 PHE A CB 1 ATOM 682 C CG . PHE A 1 92 ? -40.603 23.771 -63.015 1.00 67.84 ? 88 PHE A CG 1 ATOM 683 C CD1 . PHE A 1 92 ? -39.793 23.613 -64.124 1.00 60.58 ? 88 PHE A CD1 1 ATOM 684 C CD2 . PHE A 1 92 ? -41.973 23.828 -63.197 1.00 72.93 ? 88 PHE A CD2 1 ATOM 685 C CE1 . PHE A 1 92 ? -40.333 23.513 -65.384 1.00 65.34 ? 88 PHE A CE1 1 ATOM 686 C CE2 . PHE A 1 92 ? -42.521 23.723 -64.461 1.00 74.05 ? 88 PHE A CE2 1 ATOM 687 C CZ . PHE A 1 92 ? -41.698 23.564 -65.555 1.00 69.03 ? 88 PHE A CZ 1 ATOM 688 N N . GLY A 1 93 ? -37.697 24.621 -59.958 1.00 59.27 ? 89 GLY A N 1 ATOM 689 C CA . GLY A 1 93 ? -36.878 24.520 -58.768 1.00 48.25 ? 89 GLY A CA 1 ATOM 690 C C . GLY A 1 93 ? -35.474 24.078 -59.124 1.00 48.49 ? 89 GLY A C 1 ATOM 691 O O . GLY A 1 93 ? -35.112 24.031 -60.301 1.00 45.28 ? 89 GLY A O 1 ATOM 692 N N . SER A 1 94 ? -34.681 23.761 -58.105 1.00 56.78 ? 90 SER A N 1 ATOM 693 C CA . SER A 1 94 ? -33.303 23.328 -58.305 1.00 51.22 ? 90 SER A CA 1 ATOM 694 C C . SER A 1 94 ? -33.048 22.017 -57.577 1.00 53.01 ? 90 SER A C 1 ATOM 695 O O . SER A 1 94 ? -33.713 21.705 -56.589 1.00 48.23 ? 90 SER A O 1 ATOM 696 C CB . SER A 1 94 ? -32.326 24.396 -57.816 1.00 44.55 ? 90 SER A CB 1 ATOM 697 O OG . SER A 1 94 ? -32.693 25.676 -58.293 1.00 69.91 ? 90 SER A OG 1 ATOM 698 N N . ILE A 1 95 ? -32.084 21.252 -58.074 1.00 56.72 ? 91 ILE A N 1 ATOM 699 C CA . ILE A 1 95 ? -31.707 20.001 -57.434 1.00 51.81 ? 91 ILE A CA 1 ATOM 700 C C . ILE A 1 95 ? -30.201 19.789 -57.467 1.00 45.59 ? 91 ILE A C 1 ATOM 701 O O . ILE A 1 95 ? -29.518 20.214 -58.401 1.00 37.71 ? 91 ILE A O 1 ATOM 702 C CB . ILE A 1 95 ? -32.401 18.801 -58.095 1.00 46.68 ? 91 ILE A CB 1 ATOM 703 C CG1 . ILE A 1 95 ? -32.300 18.895 -59.620 1.00 47.25 ? 91 ILE A CG1 1 ATOM 704 C CG2 . ILE A 1 95 ? -33.859 18.732 -57.651 1.00 45.21 ? 91 ILE A CG2 1 ATOM 705 C CD1 . ILE A 1 95 ? -32.701 17.618 -60.331 1.00 42.43 ? 91 ILE A CD1 1 ATOM 706 N N . ILE A 1 96 ? -29.700 19.122 -56.432 1.00 50.25 ? 92 ILE A N 1 ATOM 707 C CA . ILE A 1 96 ? -28.275 18.865 -56.272 1.00 48.23 ? 92 ILE A CA 1 ATOM 708 C C . ILE A 1 96 ? -28.005 17.369 -56.372 1.00 38.84 ? 92 ILE A C 1 ATOM 709 O O . ILE A 1 96 ? -28.830 16.557 -55.961 1.00 36.70 ? 92 ILE A O 1 ATOM 710 C CB . ILE A 1 96 ? -27.760 19.404 -54.918 1.00 39.44 ? 92 ILE A CB 1 ATOM 711 C CG1 . ILE A 1 96 ? -27.912 20.924 -54.864 1.00 59.70 ? 92 ILE A CG1 1 ATOM 712 C CG2 . ILE A 1 96 ? -26.301 19.026 -54.697 1.00 46.07 ? 92 ILE A CG2 1 ATOM 713 C CD1 . ILE A 1 96 ? -27.651 21.518 -53.496 1.00 75.26 ? 92 ILE A CD1 1 ATOM 714 N N . SER A 1 97 ? -26.845 17.014 -56.915 1.00 43.45 ? 93 SER A N 1 ATOM 715 C CA . SER A 1 97 ? -26.455 15.617 -57.060 1.00 46.88 ? 93 SER A CA 1 ATOM 716 C C . SER A 1 97 ? -25.909 15.056 -55.752 1.00 45.18 ? 93 SER A C 1 ATOM 717 O O . SER A 1 97 ? -25.787 15.770 -54.760 1.00 50.17 ? 93 SER A O 1 ATOM 718 C CB . SER A 1 97 ? -25.400 15.474 -58.158 1.00 46.20 ? 93 SER A CB 1 ATOM 719 O OG . SER A 1 97 ? -24.193 16.116 -57.787 1.00 31.37 ? 93 SER A OG 1 ATOM 720 N N . ARG A 1 98 ? -25.571 13.773 -55.759 1.00 33.82 ? 94 ARG A N 1 ATOM 721 C CA . ARG A 1 98 ? -24.901 13.160 -54.622 1.00 47.43 ? 94 ARG A CA 1 ATOM 722 C C . ARG A 1 98 ? -23.523 13.786 -54.478 1.00 56.91 ? 94 ARG A C 1 ATOM 723 O O . ARG A 1 98 ? -22.918 14.181 -55.476 1.00 44.82 ? 94 ARG A O 1 ATOM 724 C CB . ARG A 1 98 ? -24.795 11.649 -54.809 1.00 37.63 ? 94 ARG A CB 1 ATOM 725 C CG . ARG A 1 98 ? -24.103 11.243 -56.097 1.00 45.14 ? 94 ARG A CG 1 ATOM 726 C CD . ARG A 1 98 ? -24.323 9.778 -56.396 1.00 38.09 ? 94 ARG A CD 1 ATOM 727 N NE . ARG A 1 98 ? -24.028 9.461 -57.789 1.00 41.92 ? 94 ARG A NE 1 ATOM 728 C CZ . ARG A 1 98 ? -24.276 8.285 -58.355 1.00 36.68 ? 94 ARG A CZ 1 ATOM 729 N NH1 . ARG A 1 98 ? -24.826 7.307 -57.650 1.00 39.98 ? 94 ARG A NH1 1 ATOM 730 N NH2 . ARG A 1 98 ? -23.975 8.090 -59.629 1.00 34.71 ? 94 ARG A NH2 1 ATOM 731 N N . ASP A 1 99 ? -23.029 13.887 -53.248 1.00 53.20 ? 95 ASP A N 1 ATOM 732 C CA . ASP A 1 99 ? -21.738 14.517 -53.026 1.00 50.58 ? 95 ASP A CA 1 ATOM 733 C C . ASP A 1 99 ? -20.679 13.738 -53.794 1.00 109.16 ? 95 ASP A C 1 ATOM 734 O O . ASP A 1 99 ? -20.580 12.519 -53.674 1.00 61.36 ? 95 ASP A O 1 ATOM 735 C CB . ASP A 1 99 ? -21.405 14.597 -51.527 1.00 55.68 ? 95 ASP A CB 1 ATOM 736 C CG . ASP A 1 99 ? -21.074 13.245 -50.913 1.00 69.57 ? 95 ASP A CG 1 ATOM 737 O OD1 . ASP A 1 99 ? -19.913 12.809 -51.035 1.00 78.76 ? 95 ASP A OD1 1 ATOM 738 O OD2 . ASP A 1 99 ? -21.957 12.627 -50.283 1.00 84.89 ? 95 ASP A OD2 1 ATOM 739 N N . VAL A 1 100 ? -19.921 14.451 -54.620 1.00 55.43 ? 96 VAL A N 1 ATOM 740 C CA . VAL A 1 100 ? -18.865 13.840 -55.415 1.00 47.21 ? 96 VAL A CA 1 ATOM 741 C C . VAL A 1 100 ? -17.530 14.145 -54.753 1.00 52.93 ? 96 VAL A C 1 ATOM 742 O O . VAL A 1 100 ? -17.068 15.286 -54.766 1.00 52.06 ? 96 VAL A O 1 ATOM 743 C CB . VAL A 1 100 ? -18.875 14.358 -56.871 1.00 39.92 ? 96 VAL A CB 1 ATOM 744 C CG1 . VAL A 1 100 ? -17.716 13.764 -57.671 1.00 38.03 ? 96 VAL A CG1 1 ATOM 745 C CG2 . VAL A 1 100 ? -20.214 14.041 -57.536 1.00 45.75 ? 96 VAL A CG2 1 ATOM 746 N N . HIS A 1 101 ? -16.911 13.118 -54.181 1.00 45.76 ? 97 HIS A N 1 ATOM 747 C CA . HIS A 1 101 ? -15.660 13.297 -53.464 1.00 36.31 ? 97 HIS A CA 1 ATOM 748 C C . HIS A 1 101 ? -14.508 13.096 -54.424 1.00 43.06 ? 97 HIS A C 1 ATOM 749 O O . HIS A 1 101 ? -14.256 11.985 -54.890 1.00 49.54 ? 97 HIS A O 1 ATOM 750 C CB . HIS A 1 101 ? -15.553 12.319 -52.294 1.00 42.72 ? 97 HIS A CB 1 ATOM 751 C CG . HIS A 1 101 ? -16.650 12.464 -51.288 1.00 47.16 ? 97 HIS A CG 1 ATOM 752 N ND1 . HIS A 1 101 ? -16.561 13.314 -50.206 1.00 53.51 ? 97 HIS A ND1 1 ATOM 753 C CD2 . HIS A 1 101 ? -17.864 11.871 -51.202 1.00 60.23 ? 97 HIS A CD2 1 ATOM 754 C CE1 . HIS A 1 101 ? -17.673 13.237 -49.497 1.00 73.42 ? 97 HIS A CE1 1 ATOM 755 N NE2 . HIS A 1 101 ? -18.481 12.369 -50.080 1.00 71.29 ? 97 HIS A NE2 1 ATOM 756 N N . VAL A 1 102 ? -13.810 14.186 -54.716 1.00 53.02 ? 98 VAL A N 1 ATOM 757 C CA . VAL A 1 102 ? -12.643 14.133 -55.576 1.00 46.40 ? 98 VAL A CA 1 ATOM 758 C C . VAL A 1 102 ? -11.397 14.099 -54.707 1.00 36.56 ? 98 VAL A C 1 ATOM 759 O O . VAL A 1 102 ? -11.210 14.961 -53.850 1.00 33.02 ? 98 VAL A O 1 ATOM 760 C CB . VAL A 1 102 ? -12.578 15.338 -56.539 1.00 32.85 ? 98 VAL A CB 1 ATOM 761 C CG1 . VAL A 1 102 ? -11.354 15.229 -57.453 1.00 29.21 ? 98 VAL A CG1 1 ATOM 762 C CG2 . VAL A 1 102 ? -13.859 15.428 -57.361 1.00 39.78 ? 98 VAL A CG2 1 ATOM 763 N N . ARG A 1 103 ? -10.572 13.077 -54.903 1.00 33.87 ? 99 ARG A N 1 ATOM 764 C CA . ARG A 1 103 ? -9.213 13.089 -54.388 1.00 34.18 ? 99 ARG A CA 1 ATOM 765 C C . ARG A 1 103 ? -8.272 12.788 -55.545 1.00 40.43 ? 99 ARG A C 1 ATOM 766 O O . ARG A 1 103 ? -8.266 11.687 -56.093 1.00 44.57 ? 99 ARG A O 1 ATOM 767 C CB . ARG A 1 103 ? -9.032 12.083 -53.241 1.00 44.21 ? 99 ARG A CB 1 ATOM 768 C CG . ARG A 1 103 ? -9.446 10.656 -53.556 1.00 69.82 ? 99 ARG A CG 1 ATOM 769 C CD . ARG A 1 103 ? -9.230 9.735 -52.365 1.00 68.66 ? 99 ARG A CD 1 ATOM 770 N NE . ARG A 1 103 ? -9.588 8.353 -52.675 1.00 61.92 ? 99 ARG A NE 1 ATOM 771 C CZ . ARG A 1 103 ? -9.559 7.352 -51.801 1.00 80.69 ? 99 ARG A CZ 1 ATOM 772 N NH1 . ARG A 1 103 ? -9.187 7.564 -50.546 1.00 87.63 ? 99 ARG A NH1 1 ATOM 773 N NH2 . ARG A 1 103 ? -9.904 6.131 -52.185 1.00 87.74 ? 99 ARG A NH2 1 ATOM 774 N N . ALA A 1 104 ? -7.492 13.792 -55.928 1.00 45.95 ? 100 ALA A N 1 ATOM 775 C CA . ALA A 1 104 ? -6.482 13.623 -56.959 1.00 40.09 ? 100 ALA A CA 1 ATOM 776 C C . ALA A 1 104 ? -5.157 13.419 -56.259 1.00 39.48 ? 100 ALA A C 1 ATOM 777 O O . ALA A 1 104 ? -4.798 14.184 -55.365 1.00 44.93 ? 100 ALA A O 1 ATOM 778 C CB . ALA A 1 104 ? -6.436 14.822 -57.890 1.00 39.08 ? 100 ALA A CB 1 ATOM 779 N N . VAL A 1 105 ? -4.441 12.377 -56.659 1.00 46.22 ? 101 VAL A N 1 ATOM 780 C CA . VAL A 1 105 ? -3.225 11.987 -55.968 1.00 53.44 ? 101 VAL A CA 1 ATOM 781 C C . VAL A 1 105 ? -2.044 12.023 -56.913 1.00 45.67 ? 101 VAL A C 1 ATOM 782 O O . VAL A 1 105 ? -2.078 11.446 -57.999 1.00 38.81 ? 101 VAL A O 1 ATOM 783 C CB . VAL A 1 105 ? -3.348 10.586 -55.360 1.00 51.46 ? 101 VAL A CB 1 ATOM 784 C CG1 . VAL A 1 105 ? -2.264 10.376 -54.314 1.00 77.95 ? 101 VAL A CG1 1 ATOM 785 C CG2 . VAL A 1 105 ? -4.726 10.409 -54.743 1.00 53.05 ? 101 VAL A CG2 1 ATOM 786 N N . VAL A 1 106 ? -1.001 12.723 -56.493 1.00 44.74 ? 102 VAL A N 1 ATOM 787 C CA . VAL A 1 106 ? 0.223 12.775 -57.262 1.00 56.40 ? 102 VAL A CA 1 ATOM 788 C C . VAL A 1 106 ? 0.872 11.402 -57.219 1.00 57.64 ? 102 VAL A C 1 ATOM 789 O O . VAL A 1 106 ? 0.732 10.673 -56.236 1.00 55.79 ? 102 VAL A O 1 ATOM 790 C CB . VAL A 1 106 ? 1.191 13.834 -56.719 1.00 57.38 ? 102 VAL A CB 1 ATOM 791 C CG1 . VAL A 1 106 ? 2.410 13.920 -57.604 1.00 58.81 ? 102 VAL A CG1 1 ATOM 792 C CG2 . VAL A 1 106 ? 0.501 15.187 -56.627 1.00 56.01 ? 102 VAL A CG2 1 ATOM 793 N N . ILE A 1 107 ? 1.578 11.045 -58.285 1.00 57.11 ? 103 ILE A N 1 ATOM 794 C CA . ILE A 1 107 ? 2.293 9.782 -58.306 1.00 57.69 ? 103 ILE A CA 1 ATOM 795 C C . ILE A 1 107 ? 3.420 9.870 -57.291 1.00 68.94 ? 103 ILE A C 1 ATOM 796 O O . ILE A 1 107 ? 4.271 10.757 -57.366 1.00 71.97 ? 103 ILE A O 1 ATOM 797 C CB . ILE A 1 107 ? 2.866 9.461 -59.697 1.00 58.47 ? 103 ILE A CB 1 ATOM 798 C CG1 . ILE A 1 107 ? 1.750 9.440 -60.743 1.00 59.37 ? 103 ILE A CG1 1 ATOM 799 C CG2 . ILE A 1 107 ? 3.603 8.123 -59.675 1.00 87.21 ? 103 ILE A CG2 1 ATOM 800 C CD1 . ILE A 1 107 ? 2.255 9.543 -62.162 1.00 62.82 ? 103 ILE A CD1 1 ATOM 801 N N . GLN A 1 108 ? 3.411 8.942 -56.343 1.00 71.11 ? 104 GLN A N 1 ATOM 802 C CA . GLN A 1 108 ? 4.403 8.912 -55.282 1.00 72.12 ? 104 GLN A CA 1 ATOM 803 C C . GLN A 1 108 ? 4.973 7.508 -55.184 1.00 85.49 ? 104 GLN A C 1 ATOM 804 O O . GLN A 1 108 ? 4.249 6.550 -54.909 1.00 85.59 ? 104 GLN A O 1 ATOM 805 C CB . GLN A 1 108 ? 3.790 9.351 -53.952 1.00 74.62 ? 104 GLN A CB 1 ATOM 806 C CG . GLN A 1 108 ? 4.787 9.430 -52.814 1.00 83.75 ? 104 GLN A CG 1 ATOM 807 C CD . GLN A 1 108 ? 4.273 10.253 -51.651 1.00 76.16 ? 104 GLN A CD 1 ATOM 808 O OE1 . GLN A 1 108 ? 3.066 10.366 -51.441 1.00 75.47 ? 104 GLN A OE1 1 ATOM 809 N NE2 . GLN A 1 108 ? 5.190 10.845 -50.893 1.00 73.38 ? 104 GLN A NE2 1 ATOM 810 N N . SER A 1 109 ? 6.277 7.403 -55.424 1.00 90.66 ? 105 SER A N 1 ATOM 811 C CA . SER A 1 109 ? 6.960 6.118 -55.459 1.00 81.85 ? 105 SER A CA 1 ATOM 812 C C . SER A 1 109 ? 6.685 5.322 -54.193 1.00 83.81 ? 105 SER A C 1 ATOM 813 O O . SER A 1 109 ? 6.712 5.860 -53.086 1.00 85.96 ? 105 SER A O 1 ATOM 814 C CB . SER A 1 109 ? 8.465 6.318 -55.635 1.00 100.15 ? 105 SER A CB 1 ATOM 815 O OG . SER A 1 109 ? 9.001 7.098 -54.581 1.00 96.36 ? 105 SER A OG 1 ATOM 816 N N . TYR A 1 110 ? 6.405 4.037 -54.378 1.00 78.06 ? 106 TYR A N 1 ATOM 817 C CA . TYR A 1 110 ? 6.061 3.148 -53.279 1.00 80.37 ? 106 TYR A CA 1 ATOM 818 C C . TYR A 1 110 ? 6.839 1.852 -53.415 1.00 71.24 ? 106 TYR A C 1 ATOM 819 O O . TYR A 1 110 ? 7.408 1.571 -54.470 1.00 71.53 ? 106 TYR A O 1 ATOM 820 C CB . TYR A 1 110 ? 4.558 2.865 -53.267 1.00 86.31 ? 106 TYR A CB 1 ATOM 821 C CG . TYR A 1 110 ? 4.097 1.992 -54.417 1.00 70.36 ? 106 TYR A CG 1 ATOM 822 C CD1 . TYR A 1 110 ? 4.150 2.449 -55.727 1.00 73.74 ? 106 TYR A CD1 1 ATOM 823 C CD2 . TYR A 1 110 ? 3.608 0.714 -54.193 1.00 56.70 ? 106 TYR A CD2 1 ATOM 824 C CE1 . TYR A 1 110 ? 3.732 1.656 -56.781 1.00 69.45 ? 106 TYR A CE1 1 ATOM 825 C CE2 . TYR A 1 110 ? 3.187 -0.086 -55.241 1.00 62.71 ? 106 TYR A CE2 1 ATOM 826 C CZ . TYR A 1 110 ? 3.251 0.389 -56.532 1.00 70.07 ? 106 TYR A CZ 1 ATOM 827 O OH . TYR A 1 110 ? 2.833 -0.405 -57.579 1.00 54.14 ? 106 TYR A OH 1 ATOM 828 N N . GLU A 1 111 ? 6.862 1.065 -52.344 1.00 73.93 ? 107 GLU A N 1 ATOM 829 C CA . GLU A 1 111 ? 7.543 -0.221 -52.361 1.00 71.52 ? 107 GLU A CA 1 ATOM 830 C C . GLU A 1 111 ? 6.816 -1.210 -51.459 1.00 72.34 ? 107 GLU A C 1 ATOM 831 O O . GLU A 1 111 ? 6.334 -0.845 -50.385 1.00 72.49 ? 107 GLU A O 1 ATOM 832 C CB . GLU A 1 111 ? 9.001 -0.064 -51.924 1.00 68.31 ? 107 GLU A CB 1 ATOM 833 C CG . GLU A 1 111 ? 9.956 -1.022 -52.614 1.00 66.40 ? 107 GLU A CG 1 ATOM 834 C CD . GLU A 1 111 ? 10.021 -0.802 -54.113 1.00 74.71 ? 107 GLU A CD 1 ATOM 835 O OE1 . GLU A 1 111 ? 9.419 -1.605 -54.857 1.00 82.45 ? 107 GLU A OE1 1 ATOM 836 O OE2 . GLU A 1 111 ? 10.671 0.173 -54.545 1.00 54.61 ? 107 GLU A OE2 1 ATOM 837 N N . SER A 1 112 ? 6.741 -2.460 -51.904 1.00 72.90 ? 108 SER A N 1 ATOM 838 C CA . SER A 1 112 ? 6.039 -3.503 -51.166 1.00 69.55 ? 108 SER A CA 1 ATOM 839 C C . SER A 1 112 ? 7.022 -4.420 -50.449 1.00 69.29 ? 108 SER A C 1 ATOM 840 O O . SER A 1 112 ? 7.980 -4.915 -51.045 1.00 66.70 ? 108 SER A O 1 ATOM 841 C CB . SER A 1 112 ? 5.145 -4.315 -52.106 1.00 59.50 ? 108 SER A CB 1 ATOM 842 O OG . SER A 1 112 ? 5.757 -4.493 -53.370 1.00 70.38 ? 108 SER A OG 1 ATOM 843 N N . GLU A 1 113 ? 6.773 -4.629 -49.161 1.00 80.36 ? 109 GLU A N 1 ATOM 844 C CA . GLU A 1 113 ? 7.594 -5.502 -48.335 1.00 82.15 ? 109 GLU A CA 1 ATOM 845 C C . GLU A 1 113 ? 6.881 -6.836 -48.132 1.00 95.75 ? 109 GLU A C 1 ATOM 846 O O . GLU A 1 113 ? 5.867 -6.907 -47.440 1.00 96.46 ? 109 GLU A O 1 ATOM 847 C CB . GLU A 1 113 ? 7.888 -4.829 -46.987 1.00 82.03 ? 109 GLU A CB 1 ATOM 848 C CG . GLU A 1 113 ? 8.613 -5.694 -45.963 1.00 96.61 ? 109 GLU A CG 1 ATOM 849 C CD . GLU A 1 113 ? 7.879 -5.756 -44.633 1.00 112.71 ? 109 GLU A CD 1 ATOM 850 O OE1 . GLU A 1 113 ? 8.436 -5.297 -43.615 1.00 118.91 ? 109 GLU A OE1 1 ATOM 851 O OE2 . GLU A 1 113 ? 6.742 -6.268 -44.605 1.00 130.40 ? 109 GLU A OE2 1 ATOM 852 N N . ALA A 1 114 ? 7.409 -7.892 -48.743 1.00 100.74 ? 110 ALA A N 1 ATOM 853 C CA . ALA A 1 114 ? 6.887 -9.236 -48.519 1.00 86.96 ? 110 ALA A CA 1 ATOM 854 C C . ALA A 1 114 ? 7.536 -9.789 -47.261 1.00 87.21 ? 110 ALA A C 1 ATOM 855 O O . ALA A 1 114 ? 8.759 -9.913 -47.187 1.00 92.92 ? 110 ALA A O 1 ATOM 856 C CB . ALA A 1 114 ? 7.156 -10.138 -49.716 1.00 62.90 ? 110 ALA A CB 1 ATOM 857 N N . ASP A 1 115 ? 6.712 -10.112 -46.271 1.00 75.08 ? 111 ASP A N 1 ATOM 858 C CA . ASP A 1 115 ? 7.208 -10.427 -44.938 1.00 92.52 ? 111 ASP A CA 1 ATOM 859 C C . ASP A 1 115 ? 7.478 -11.916 -44.760 1.00 89.92 ? 111 ASP A C 1 ATOM 860 O O . ASP A 1 115 ? 6.644 -12.754 -45.107 1.00 93.42 ? 111 ASP A O 1 ATOM 861 C CB . ASP A 1 115 ? 6.205 -9.954 -43.881 1.00 107.86 ? 111 ASP A CB 1 ATOM 862 C CG . ASP A 1 115 ? 6.836 -9.777 -42.508 1.00 118.02 ? 111 ASP A CG 1 ATOM 863 O OD1 . ASP A 1 115 ? 8.017 -9.373 -42.439 1.00 121.78 ? 111 ASP A OD1 1 ATOM 864 O OD2 . ASP A 1 115 ? 6.150 -10.036 -41.497 1.00 122.00 ? 111 ASP A OD2 1 ATOM 865 N N . ASN A 1 116 ? 8.651 -12.240 -44.225 1.00 87.36 ? 112 ASN A N 1 ATOM 866 C CA . ASN A 1 116 ? 8.949 -13.607 -43.825 1.00 82.98 ? 112 ASN A CA 1 ATOM 867 C C . ASN A 1 116 ? 7.990 -14.026 -42.718 1.00 83.82 ? 112 ASN A C 1 ATOM 868 O O . ASN A 1 116 ? 7.841 -13.322 -41.719 1.00 90.00 ? 112 ASN A O 1 ATOM 869 C CB . ASN A 1 116 ? 10.399 -13.738 -43.354 1.00 77.23 ? 112 ASN A CB 1 ATOM 870 C CG . ASN A 1 116 ? 11.400 -13.377 -44.435 1.00 82.38 ? 112 ASN A CG 1 ATOM 871 O OD1 . ASN A 1 116 ? 11.559 -14.102 -45.417 1.00 77.41 ? 112 ASN A OD1 1 ATOM 872 N ND2 . ASN A 1 116 ? 12.094 -12.260 -44.251 1.00 81.02 ? 112 ASN A ND2 1 ATOM 873 N N . GLU A 1 117 ? 7.341 -15.171 -42.905 1.00 71.32 ? 113 GLU A N 1 ATOM 874 C CA . GLU A 1 117 ? 6.314 -15.638 -41.980 1.00 79.56 ? 113 GLU A CA 1 ATOM 875 C C . GLU A 1 117 ? 6.737 -16.943 -41.312 1.00 74.99 ? 113 GLU A C 1 ATOM 876 O O . GLU A 1 117 ? 7.084 -17.915 -41.984 1.00 66.65 ? 113 GLU A O 1 ATOM 877 C CB . GLU A 1 117 ? 4.984 -15.812 -42.716 1.00 87.24 ? 113 GLU A CB 1 ATOM 878 C CG . GLU A 1 117 ? 4.347 -14.491 -43.139 1.00 91.46 ? 113 GLU A CG 1 ATOM 879 C CD . GLU A 1 117 ? 3.543 -13.840 -42.028 1.00 95.77 ? 113 GLU A CD 1 ATOM 880 O OE1 . GLU A 1 117 ? 2.756 -12.917 -42.328 1.00 99.06 ? 113 GLU A OE1 1 ATOM 881 O OE2 . GLU A 1 117 ? 3.698 -14.244 -40.857 1.00 103.43 ? 113 GLU A OE2 1 ATOM 882 N N . TYR A 1 118 ? 6.712 -16.948 -39.982 1.00 76.15 ? 114 TYR A N 1 ATOM 883 C CA . TYR A 1 118 ? 7.138 -18.101 -39.199 1.00 59.83 ? 114 TYR A CA 1 ATOM 884 C C . TYR A 1 118 ? 6.025 -19.129 -39.093 1.00 73.67 ? 114 TYR A C 1 ATOM 885 O O . TYR A 1 118 ? 4.847 -18.780 -39.010 1.00 86.22 ? 114 TYR A O 1 ATOM 886 C CB . TYR A 1 118 ? 7.588 -17.659 -37.811 1.00 75.17 ? 114 TYR A CB 1 ATOM 887 C CG . TYR A 1 118 ? 8.809 -16.776 -37.855 1.00 101.38 ? 114 TYR A CG 1 ATOM 888 C CD1 . TYR A 1 118 ? 10.076 -17.300 -37.646 1.00 92.27 ? 114 TYR A CD1 1 ATOM 889 C CD2 . TYR A 1 118 ? 8.697 -15.419 -38.122 1.00 106.22 ? 114 TYR A CD2 1 ATOM 890 C CE1 . TYR A 1 118 ? 11.196 -16.497 -37.693 1.00 96.18 ? 114 TYR A CE1 1 ATOM 891 C CE2 . TYR A 1 118 ? 9.811 -14.608 -38.172 1.00 107.69 ? 114 TYR A CE2 1 ATOM 892 C CZ . TYR A 1 118 ? 11.059 -15.151 -37.957 1.00 109.09 ? 114 TYR A CZ 1 ATOM 893 O OH . TYR A 1 118 ? 12.172 -14.344 -38.006 1.00 105.47 ? 114 TYR A OH 1 ATOM 894 N N . VAL A 1 119 ? 6.413 -20.399 -39.095 1.00 77.68 ? 115 VAL A N 1 ATOM 895 C CA . VAL A 1 119 ? 5.458 -21.493 -39.182 1.00 72.43 ? 115 VAL A CA 1 ATOM 896 C C . VAL A 1 119 ? 6.024 -22.767 -38.565 1.00 65.93 ? 115 VAL A C 1 ATOM 897 O O . VAL A 1 119 ? 7.240 -22.942 -38.488 1.00 65.13 ? 115 VAL A O 1 ATOM 898 C CB . VAL A 1 119 ? 5.066 -21.756 -40.658 1.00 60.37 ? 115 VAL A CB 1 ATOM 899 C CG1 . VAL A 1 119 ? 6.313 -21.928 -41.518 1.00 54.99 ? 115 VAL A CG1 1 ATOM 900 C CG2 . VAL A 1 119 ? 4.139 -22.966 -40.788 1.00 55.05 ? 115 VAL A CG2 1 ATOM 901 N N . ILE A 1 120 ? 5.130 -23.642 -38.112 1.00 61.22 ? 116 ILE A N 1 ATOM 902 C CA . ILE A 1 120 ? 5.497 -25.001 -37.730 1.00 59.09 ? 116 ILE A CA 1 ATOM 903 C C . ILE A 1 120 ? 5.013 -25.958 -38.812 1.00 56.58 ? 116 ILE A C 1 ATOM 904 O O . ILE A 1 120 ? 3.901 -25.818 -39.322 1.00 65.91 ? 116 ILE A O 1 ATOM 905 C CB . ILE A 1 120 ? 4.903 -25.391 -36.364 1.00 50.85 ? 116 ILE A CB 1 ATOM 906 C CG1 . ILE A 1 120 ? 5.487 -24.477 -35.282 1.00 49.76 ? 116 ILE A CG1 1 ATOM 907 C CG2 . ILE A 1 120 ? 5.171 -26.873 -36.060 1.00 53.25 ? 116 ILE A CG2 1 ATOM 908 C CD1 . ILE A 1 120 ? 5.178 -24.892 -33.856 1.00 54.18 ? 116 ILE A CD1 1 ATOM 909 N N . ARG A 1 121 ? 5.855 -26.928 -39.156 1.00 57.69 ? 117 ARG A N 1 ATOM 910 C CA . ARG A 1 121 ? 5.557 -27.864 -40.235 1.00 62.54 ? 117 ARG A CA 1 ATOM 911 C C . ARG A 1 121 ? 4.213 -28.559 -40.039 1.00 53.36 ? 117 ARG A C 1 ATOM 912 O O . ARG A 1 121 ? 3.856 -28.944 -38.925 1.00 49.98 ? 117 ARG A O 1 ATOM 913 C CB . ARG A 1 121 ? 6.664 -28.913 -40.355 1.00 73.83 ? 117 ARG A CB 1 ATOM 914 C CG . ARG A 1 121 ? 6.347 -30.011 -41.355 1.00 67.33 ? 117 ARG A CG 1 ATOM 915 C CD . ARG A 1 121 ? 7.606 -30.623 -41.939 1.00 67.79 ? 117 ARG A CD 1 ATOM 916 N NE . ARG A 1 121 ? 8.403 -31.322 -40.935 1.00 81.14 ? 117 ARG A NE 1 ATOM 917 C CZ . ARG A 1 121 ? 9.633 -31.781 -41.145 1.00 89.67 ? 117 ARG A CZ 1 ATOM 918 N NH1 . ARG A 1 121 ? 10.283 -32.404 -40.172 1.00 90.84 ? 117 ARG A NH1 1 ATOM 919 N NH2 . ARG A 1 121 ? 10.220 -31.613 -42.322 1.00 86.43 ? 117 ARG A NH2 1 ATOM 920 N N . GLY A 1 122 ? 3.474 -28.703 -41.134 1.00 54.50 ? 118 GLY A N 1 ATOM 921 C CA . GLY A 1 122 ? 2.181 -29.361 -41.116 1.00 69.13 ? 118 GLY A CA 1 ATOM 922 C C . GLY A 1 122 ? 1.044 -28.366 -41.002 1.00 59.94 ? 118 GLY A C 1 ATOM 923 O O . GLY A 1 122 ? -0.091 -28.664 -41.376 1.00 67.15 ? 118 GLY A O 1 ATOM 924 N N . ASN A 1 123 ? 1.348 -27.179 -40.485 1.00 50.13 ? 119 ASN A N 1 ATOM 925 C CA . ASN A 1 123 ? 0.360 -26.113 -40.397 1.00 47.11 ? 119 ASN A CA 1 ATOM 926 C C . ASN A 1 123 ? 0.238 -25.362 -41.714 1.00 53.31 ? 119 ASN A C 1 ATOM 927 O O . ASN A 1 123 ? 1.227 -25.154 -42.417 1.00 61.56 ? 119 ASN A O 1 ATOM 928 C CB . ASN A 1 123 ? 0.712 -25.130 -39.278 1.00 44.83 ? 119 ASN A CB 1 ATOM 929 C CG . ASN A 1 123 ? 0.604 -25.747 -37.901 1.00 39.80 ? 119 ASN A CG 1 ATOM 930 O OD1 . ASN A 1 123 ? -0.480 -25.809 -37.323 1.00 58.86 ? 119 ASN A OD1 1 ATOM 931 N ND2 . ASN A 1 123 ? 1.729 -26.194 -37.361 1.00 46.08 ? 119 ASN A ND2 1 ATOM 932 N N . SER A 1 124 ? -0.985 -24.962 -42.046 1.00 53.29 ? 120 SER A N 1 ATOM 933 C CA . SER A 1 124 ? -1.224 -24.130 -43.213 1.00 51.66 ? 120 SER A CA 1 ATOM 934 C C . SER A 1 124 ? -0.856 -22.696 -42.867 1.00 52.03 ? 120 SER A C 1 ATOM 935 O O . SER A 1 124 ? -0.921 -22.304 -41.700 1.00 59.86 ? 120 SER A O 1 ATOM 936 C CB . SER A 1 124 ? -2.681 -24.229 -43.658 1.00 58.31 ? 120 SER A CB 1 ATOM 937 O OG . SER A 1 124 ? -3.028 -25.572 -43.950 1.00 70.64 ? 120 SER A OG 1 ATOM 938 N N . VAL A 1 125 ? -0.460 -21.921 -43.872 1.00 54.50 ? 121 VAL A N 1 ATOM 939 C CA . VAL A 1 125 ? -0.050 -20.540 -43.646 1.00 65.84 ? 121 VAL A CA 1 ATOM 940 C C . VAL A 1 125 ? -0.646 -19.574 -44.655 1.00 64.93 ? 121 VAL A C 1 ATOM 941 O O . VAL A 1 125 ? -1.053 -19.957 -45.755 1.00 56.86 ? 121 VAL A O 1 ATOM 942 C CB . VAL A 1 125 ? 1.486 -20.388 -43.689 1.00 57.16 ? 121 VAL A CB 1 ATOM 943 C CG1 . VAL A 1 125 ? 2.134 -21.246 -42.613 1.00 67.64 ? 121 VAL A CG1 1 ATOM 944 C CG2 . VAL A 1 125 ? 2.032 -20.732 -45.078 1.00 53.91 ? 121 VAL A CG2 1 ATOM 945 N N . VAL A 1 126 ? -0.686 -18.311 -44.250 1.00 58.05 ? 122 VAL A N 1 ATOM 946 C CA . VAL A 1 126 ? -1.088 -17.216 -45.114 1.00 60.11 ? 122 VAL A CA 1 ATOM 947 C C . VAL A 1 126 ? -0.063 -16.106 -44.962 1.00 67.26 ? 122 VAL A C 1 ATOM 948 O O . VAL A 1 126 ? 0.116 -15.571 -43.866 1.00 78.14 ? 122 VAL A O 1 ATOM 949 C CB . VAL A 1 126 ? -2.489 -16.687 -44.761 1.00 65.51 ? 122 VAL A CB 1 ATOM 950 C CG1 . VAL A 1 126 ? -2.853 -15.510 -45.654 1.00 60.28 ? 122 VAL A CG1 1 ATOM 951 C CG2 . VAL A 1 126 ? -3.522 -17.798 -44.886 1.00 76.58 ? 122 VAL A CG2 1 ATOM 952 N N . MET A 1 127 ? 0.616 -15.773 -46.054 1.00 53.09 ? 123 MET A N 1 ATOM 953 C CA . MET A 1 127 ? 1.588 -14.692 -46.029 1.00 73.16 ? 123 MET A CA 1 ATOM 954 C C . MET A 1 127 ? 1.047 -13.481 -46.768 1.00 80.56 ? 123 MET A C 1 ATOM 955 O O . MET A 1 127 ? 0.316 -13.598 -47.754 1.00 72.73 ? 123 MET A O 1 ATOM 956 C CB . MET A 1 127 ? 2.925 -15.136 -46.619 1.00 84.90 ? 123 MET A CB 1 ATOM 957 C CG . MET A 1 127 ? 2.843 -15.909 -47.918 1.00 69.71 ? 123 MET A CG 1 ATOM 958 S SD . MET A 1 127 ? 4.476 -16.109 -48.664 1.00 95.64 ? 123 MET A SD 1 ATOM 959 C CE . MET A 1 127 ? 5.452 -16.614 -47.246 1.00 60.73 ? 123 MET A CE 1 ATOM 960 N N . LYS A 1 128 ? 1.436 -12.316 -46.269 1.00 84.64 ? 124 LYS A N 1 ATOM 961 C CA . LYS A 1 128 ? 0.802 -11.059 -46.610 1.00 87.18 ? 124 LYS A CA 1 ATOM 962 C C . LYS A 1 128 ? 1.780 -10.139 -47.319 1.00 93.33 ? 124 LYS A C 1 ATOM 963 O O . LYS A 1 128 ? 2.981 -10.177 -47.051 1.00 84.07 ? 124 LYS A O 1 ATOM 964 C CB . LYS A 1 128 ? 0.275 -10.408 -45.331 1.00 102.67 ? 124 LYS A CB 1 ATOM 965 C CG . LYS A 1 128 ? -0.413 -9.065 -45.505 1.00 102.03 ? 124 LYS A CG 1 ATOM 966 C CD . LYS A 1 128 ? -0.953 -8.555 -44.167 1.00 115.02 ? 124 LYS A CD 1 ATOM 967 C CE . LYS A 1 128 ? 0.159 -8.304 -43.148 1.00 122.38 ? 124 LYS A CE 1 ATOM 968 N NZ . LYS A 1 128 ? -0.368 -7.910 -41.814 1.00 105.42 ? 124 LYS A NZ 1 ATOM 969 N N . CYS A 1 129 ? 1.265 -9.319 -48.228 1.00 94.77 ? 125 CYS A N 1 ATOM 970 C CA . CYS A 1 129 ? 2.073 -8.287 -48.854 1.00 83.56 ? 125 CYS A CA 1 ATOM 971 C C . CYS A 1 129 ? 1.875 -7.018 -48.042 1.00 80.91 ? 125 CYS A C 1 ATOM 972 O O . CYS A 1 129 ? 0.801 -6.420 -48.075 1.00 94.50 ? 125 CYS A O 1 ATOM 973 C CB . CYS A 1 129 ? 1.662 -8.080 -50.316 1.00 75.97 ? 125 CYS A CB 1 ATOM 974 S SG . CYS A 1 129 ? 2.933 -7.330 -51.356 1.00 108.17 ? 125 CYS A SG 1 ATOM 975 N N . GLU A 1 130 ? 2.905 -6.603 -47.310 1.00 82.43 ? 126 GLU A N 1 ATOM 976 C CA . GLU A 1 130 ? 2.780 -5.410 -46.486 1.00 84.73 ? 126 GLU A CA 1 ATOM 977 C C . GLU A 1 130 ? 2.827 -4.195 -47.389 1.00 79.68 ? 126 GLU A C 1 ATOM 978 O O . GLU A 1 130 ? 3.801 -3.982 -48.111 1.00 70.67 ? 126 GLU A O 1 ATOM 979 C CB . GLU A 1 130 ? 3.880 -5.329 -45.427 1.00 93.86 ? 126 GLU A CB 1 ATOM 980 C CG . GLU A 1 130 ? 3.676 -6.261 -44.247 1.00 100.54 ? 126 GLU A CG 1 ATOM 981 C CD . GLU A 1 130 ? 4.632 -5.972 -43.103 1.00 131.78 ? 126 GLU A CD 1 ATOM 982 O OE1 . GLU A 1 130 ? 4.795 -4.786 -42.743 1.00 148.44 ? 126 GLU A OE1 1 ATOM 983 O OE2 . GLU A 1 130 ? 5.224 -6.930 -42.563 1.00 133.50 ? 126 GLU A OE2 1 ATOM 984 N N . ILE A 1 131 ? 1.765 -3.402 -47.338 1.00 90.52 ? 127 ILE A N 1 ATOM 985 C CA . ILE A 1 131 ? 1.648 -2.220 -48.175 1.00 71.63 ? 127 ILE A CA 1 ATOM 986 C C . ILE A 1 131 ? 1.429 -1.011 -47.275 1.00 63.70 ? 127 ILE A C 1 ATOM 987 O O . ILE A 1 131 ? 0.718 -1.107 -46.274 1.00 64.63 ? 127 ILE A O 1 ATOM 988 C CB . ILE A 1 131 ? 0.493 -2.361 -49.189 1.00 67.06 ? 127 ILE A CB 1 ATOM 989 C CG1 . ILE A 1 131 ? 0.770 -3.532 -50.136 1.00 81.05 ? 127 ILE A CG1 1 ATOM 990 C CG2 . ILE A 1 131 ? 0.315 -1.076 -49.987 1.00 46.05 ? 127 ILE A CG2 1 ATOM 991 C CD1 . ILE A 1 131 ? -0.408 -3.923 -50.999 1.00 63.90 ? 127 ILE A CD1 1 ATOM 992 N N . PRO A 1 132 ? 2.045 0.132 -47.619 1.00 64.35 ? 128 PRO A N 1 ATOM 993 C CA . PRO A 1 132 ? 1.877 1.313 -46.766 1.00 61.94 ? 128 PRO A CA 1 ATOM 994 C C . PRO A 1 132 ? 0.426 1.773 -46.667 1.00 63.81 ? 128 PRO A C 1 ATOM 995 O O . PRO A 1 132 ? -0.387 1.462 -47.538 1.00 66.13 ? 128 PRO A O 1 ATOM 996 C CB . PRO A 1 132 ? 2.737 2.374 -47.459 1.00 55.53 ? 128 PRO A CB 1 ATOM 997 C CG . PRO A 1 132 ? 3.721 1.608 -48.269 1.00 52.20 ? 128 PRO A CG 1 ATOM 998 C CD . PRO A 1 132 ? 3.001 0.378 -48.715 1.00 54.05 ? 128 PRO A CD 1 ATOM 999 N N . SER A 1 133 ? 0.118 2.504 -45.600 1.00 57.74 ? 129 SER A N 1 ATOM 1000 C CA . SER A 1 133 ? -1.228 3.002 -45.356 1.00 43.19 ? 129 SER A CA 1 ATOM 1001 C C . SER A 1 133 ? -1.720 3.892 -46.495 1.00 54.78 ? 129 SER A C 1 ATOM 1002 O O . SER A 1 133 ? -2.897 3.854 -46.857 1.00 75.68 ? 129 SER A O 1 ATOM 1003 C CB . SER A 1 133 ? -1.268 3.783 -44.039 1.00 48.10 ? 129 SER A CB 1 ATOM 1004 O OG . SER A 1 133 ? -0.588 3.090 -43.005 1.00 59.79 ? 129 SER A OG 1 ATOM 1005 N N . TYR A 1 134 ? -0.813 4.681 -47.065 1.00 48.10 ? 130 TYR A N 1 ATOM 1006 C CA . TYR A 1 134 ? -1.206 5.758 -47.969 1.00 52.71 ? 130 TYR A CA 1 ATOM 1007 C C . TYR A 1 134 ? -1.544 5.277 -49.390 1.00 59.87 ? 130 TYR A C 1 ATOM 1008 O O . TYR A 1 134 ? -2.430 5.845 -50.032 1.00 75.79 ? 130 TYR A O 1 ATOM 1009 C CB . TYR A 1 134 ? -0.110 6.842 -48.012 1.00 63.62 ? 130 TYR A CB 1 ATOM 1010 C CG . TYR A 1 134 ? 1.268 6.380 -48.454 1.00 57.46 ? 130 TYR A CG 1 ATOM 1011 C CD1 . TYR A 1 134 ? 1.654 6.473 -49.782 1.00 69.14 ? 130 TYR A CD1 1 ATOM 1012 C CD2 . TYR A 1 134 ? 2.189 5.878 -47.543 1.00 49.29 ? 130 TYR A CD2 1 ATOM 1013 C CE1 . TYR A 1 134 ? 2.910 6.062 -50.197 1.00 72.20 ? 130 TYR A CE1 1 ATOM 1014 C CE2 . TYR A 1 134 ? 3.449 5.464 -47.951 1.00 69.72 ? 130 TYR A CE2 1 ATOM 1015 C CZ . TYR A 1 134 ? 3.801 5.558 -49.279 1.00 78.63 ? 130 TYR A CZ 1 ATOM 1016 O OH . TYR A 1 134 ? 5.046 5.147 -49.696 1.00 69.60 ? 130 TYR A OH 1 ATOM 1017 N N . VAL A 1 135 ? -0.854 4.247 -49.881 1.00 49.20 ? 131 VAL A N 1 ATOM 1018 C CA . VAL A 1 135 ? -1.169 3.672 -51.197 1.00 56.13 ? 131 VAL A CA 1 ATOM 1019 C C . VAL A 1 135 ? -2.188 2.537 -51.129 1.00 61.19 ? 131 VAL A C 1 ATOM 1020 O O . VAL A 1 135 ? -2.719 2.119 -52.161 1.00 50.97 ? 131 VAL A O 1 ATOM 1021 C CB . VAL A 1 135 ? 0.084 3.107 -51.910 1.00 45.49 ? 131 VAL A CB 1 ATOM 1022 C CG1 . VAL A 1 135 ? 0.952 4.226 -52.452 1.00 56.64 ? 131 VAL A CG1 1 ATOM 1023 C CG2 . VAL A 1 135 ? 0.867 2.173 -50.985 1.00 65.31 ? 131 VAL A CG2 1 ATOM 1024 N N . ALA A 1 136 ? -2.459 2.051 -49.919 1.00 59.76 ? 132 ALA A N 1 ATOM 1025 C CA . ALA A 1 136 ? -3.258 0.841 -49.719 1.00 59.92 ? 132 ALA A CA 1 ATOM 1026 C C . ALA A 1 136 ? -4.579 0.898 -50.474 1.00 64.52 ? 132 ALA A C 1 ATOM 1027 O O . ALA A 1 136 ? -5.079 -0.122 -50.952 1.00 76.26 ? 132 ALA A O 1 ATOM 1028 C CB . ALA A 1 136 ? -3.515 0.620 -48.232 1.00 55.84 ? 132 ALA A CB 1 ATOM 1029 N N . ASP A 1 137 ? -5.134 2.099 -50.583 1.00 63.19 ? 133 ASP A N 1 ATOM 1030 C CA . ASP A 1 137 ? -6.405 2.295 -51.268 1.00 66.02 ? 133 ASP A CA 1 ATOM 1031 C C . ASP A 1 137 ? -6.250 2.176 -52.786 1.00 68.13 ? 133 ASP A C 1 ATOM 1032 O O . ASP A 1 137 ? -7.147 1.676 -53.466 1.00 69.32 ? 133 ASP A O 1 ATOM 1033 C CB . ASP A 1 137 ? -7.009 3.659 -50.898 1.00 74.36 ? 133 ASP A CB 1 ATOM 1034 C CG . ASP A 1 137 ? -5.983 4.781 -50.900 1.00 83.89 ? 133 ASP A CG 1 ATOM 1035 O OD1 . ASP A 1 137 ? -4.772 4.483 -50.967 1.00 82.45 ? 133 ASP A OD1 1 ATOM 1036 O OD2 . ASP A 1 137 ? -6.391 5.959 -50.818 1.00 78.48 ? 133 ASP A OD2 1 ATOM 1037 N N . PHE A 1 138 ? -5.111 2.626 -53.305 1.00 66.03 ? 134 PHE A N 1 ATOM 1038 C CA . PHE A 1 138 ? -4.879 2.668 -54.750 1.00 62.33 ? 134 PHE A CA 1 ATOM 1039 C C . PHE A 1 138 ? -4.098 1.476 -55.296 1.00 61.51 ? 134 PHE A C 1 ATOM 1040 O O . PHE A 1 138 ? -3.895 1.375 -56.507 1.00 55.97 ? 134 PHE A O 1 ATOM 1041 C CB . PHE A 1 138 ? -4.143 3.956 -55.113 1.00 61.73 ? 134 PHE A CB 1 ATOM 1042 C CG . PHE A 1 138 ? -4.923 5.194 -54.798 1.00 65.45 ? 134 PHE A CG 1 ATOM 1043 C CD1 . PHE A 1 138 ? -5.986 5.574 -55.595 1.00 54.26 ? 134 PHE A CD1 1 ATOM 1044 C CD2 . PHE A 1 138 ? -4.608 5.967 -53.697 1.00 61.16 ? 134 PHE A CD2 1 ATOM 1045 C CE1 . PHE A 1 138 ? -6.713 6.705 -55.307 1.00 61.10 ? 134 PHE A CE1 1 ATOM 1046 C CE2 . PHE A 1 138 ? -5.333 7.100 -53.404 1.00 65.79 ? 134 PHE A CE2 1 ATOM 1047 C CZ . PHE A 1 138 ? -6.388 7.469 -54.210 1.00 69.88 ? 134 PHE A CZ 1 ATOM 1048 N N . VAL A 1 139 ? -3.674 0.572 -54.417 1.00 64.83 ? 135 VAL A N 1 ATOM 1049 C CA . VAL A 1 139 ? -2.812 -0.535 -54.828 1.00 61.77 ? 135 VAL A CA 1 ATOM 1050 C C . VAL A 1 139 ? -3.287 -1.866 -54.264 1.00 61.45 ? 135 VAL A C 1 ATOM 1051 O O . VAL A 1 139 ? -3.818 -1.940 -53.155 1.00 62.20 ? 135 VAL A O 1 ATOM 1052 C CB . VAL A 1 139 ? -1.344 -0.294 -54.396 1.00 58.33 ? 135 VAL A CB 1 ATOM 1053 C CG1 . VAL A 1 139 ? -0.470 -1.516 -54.696 1.00 61.49 ? 135 VAL A CG1 1 ATOM 1054 C CG2 . VAL A 1 139 ? -0.789 0.943 -55.092 1.00 57.07 ? 135 VAL A CG2 1 ATOM 1055 N N . PHE A 1 140 ? -3.090 -2.913 -55.056 1.00 59.71 ? 136 PHE A N 1 ATOM 1056 C CA . PHE A 1 140 ? -3.384 -4.273 -54.636 1.00 59.70 ? 136 PHE A CA 1 ATOM 1057 C C . PHE A 1 140 ? -2.448 -5.237 -55.352 1.00 57.39 ? 136 PHE A C 1 ATOM 1058 O O . PHE A 1 140 ? -1.636 -4.823 -56.181 1.00 47.26 ? 136 PHE A O 1 ATOM 1059 C CB . PHE A 1 140 ? -4.841 -4.625 -54.926 1.00 63.80 ? 136 PHE A CB 1 ATOM 1060 C CG . PHE A 1 140 ? -5.218 -4.492 -56.373 1.00 68.86 ? 136 PHE A CG 1 ATOM 1061 C CD1 . PHE A 1 140 ? -5.157 -5.584 -57.223 1.00 67.39 ? 136 PHE A CD1 1 ATOM 1062 C CD2 . PHE A 1 140 ? -5.632 -3.275 -56.886 1.00 69.40 ? 136 PHE A CD2 1 ATOM 1063 C CE1 . PHE A 1 140 ? -5.503 -5.464 -58.554 1.00 62.51 ? 136 PHE A CE1 1 ATOM 1064 C CE2 . PHE A 1 140 ? -5.980 -3.151 -58.218 1.00 75.25 ? 136 PHE A CE2 1 ATOM 1065 C CZ . PHE A 1 140 ? -5.915 -4.247 -59.051 1.00 71.45 ? 136 PHE A CZ 1 ATOM 1066 N N . VAL A 1 141 ? -2.575 -6.523 -55.040 1.00 47.12 ? 137 VAL A N 1 ATOM 1067 C CA . VAL A 1 141 ? -1.684 -7.536 -55.592 1.00 31.31 ? 137 VAL A CA 1 ATOM 1068 C C . VAL A 1 141 ? -2.148 -7.976 -56.975 1.00 33.26 ? 137 VAL A C 1 ATOM 1069 O O . VAL A 1 141 ? -3.301 -8.367 -57.160 1.00 53.13 ? 137 VAL A O 1 ATOM 1070 C CB . VAL A 1 141 ? -1.595 -8.769 -54.673 1.00 26.38 ? 137 VAL A CB 1 ATOM 1071 C CG1 . VAL A 1 141 ? -0.498 -9.714 -55.156 1.00 39.65 ? 137 VAL A CG1 1 ATOM 1072 C CG2 . VAL A 1 141 ? -1.340 -8.339 -53.231 1.00 32.93 ? 137 VAL A CG2 1 ATOM 1073 N N . ASP A 1 142 ? -1.241 -7.899 -57.944 1.00 31.20 ? 138 ASP A N 1 ATOM 1074 C CA . ASP A 1 142 ? -1.524 -8.350 -59.299 1.00 37.78 ? 138 ASP A CA 1 ATOM 1075 C C . ASP A 1 142 ? -1.401 -9.868 -59.361 1.00 57.76 ? 138 ASP A C 1 ATOM 1076 O O . ASP A 1 142 ? -2.234 -10.545 -59.967 1.00 59.39 ? 138 ASP A O 1 ATOM 1077 C CB . ASP A 1 142 ? -0.572 -7.685 -60.297 1.00 43.16 ? 138 ASP A CB 1 ATOM 1078 C CG . ASP A 1 142 ? -0.933 -7.984 -61.741 1.00 52.78 ? 138 ASP A CG 1 ATOM 1079 O OD1 . ASP A 1 142 ? -2.048 -8.487 -61.991 1.00 68.44 ? 138 ASP A OD1 1 ATOM 1080 O OD2 . ASP A 1 142 ? -0.102 -7.704 -62.630 1.00 58.12 ? 138 ASP A OD2 1 ATOM 1081 N N . LEU A 1 143 ? -0.363 -10.396 -58.717 1.00 61.19 ? 139 LEU A N 1 ATOM 1082 C CA . LEU A 1 143 ? -0.160 -11.839 -58.621 1.00 52.61 ? 139 LEU A CA 1 ATOM 1083 C C . LEU A 1 143 ? 0.924 -12.167 -57.602 1.00 48.29 ? 139 LEU A C 1 ATOM 1084 O O . LEU A 1 143 ? 1.507 -11.271 -56.990 1.00 47.68 ? 139 LEU A O 1 ATOM 1085 C CB . LEU A 1 143 ? 0.210 -12.431 -59.985 1.00 40.87 ? 139 LEU A CB 1 ATOM 1086 C CG . LEU A 1 143 ? 1.507 -11.940 -60.636 1.00 47.98 ? 139 LEU A CG 1 ATOM 1087 C CD1 . LEU A 1 143 ? 2.723 -12.769 -60.208 1.00 49.03 ? 139 LEU A CD1 1 ATOM 1088 C CD2 . LEU A 1 143 ? 1.371 -11.938 -62.155 1.00 62.47 ? 139 LEU A CD2 1 ATOM 1089 N N . TRP A 1 144 ? 1.182 -13.462 -57.431 1.00 46.01 ? 140 TRP A N 1 ATOM 1090 C CA . TRP A 1 144 ? 2.286 -13.941 -56.603 1.00 40.93 ? 140 TRP A CA 1 ATOM 1091 C C . TRP A 1 144 ? 3.276 -14.703 -57.468 1.00 33.02 ? 140 TRP A C 1 ATOM 1092 O O . TRP A 1 144 ? 2.901 -15.301 -58.476 1.00 39.31 ? 140 TRP A O 1 ATOM 1093 C CB . TRP A 1 144 ? 1.783 -14.833 -55.471 1.00 39.77 ? 140 TRP A CB 1 ATOM 1094 C CG . TRP A 1 144 ? 1.299 -14.068 -54.278 1.00 45.53 ? 140 TRP A CG 1 ATOM 1095 C CD1 . TRP A 1 144 ? 0.020 -13.673 -54.023 1.00 40.73 ? 140 TRP A CD1 1 ATOM 1096 C CD2 . TRP A 1 144 ? 2.089 -13.603 -53.176 1.00 46.22 ? 140 TRP A CD2 1 ATOM 1097 N NE1 . TRP A 1 144 ? -0.038 -12.993 -52.831 1.00 40.52 ? 140 TRP A NE1 1 ATOM 1098 C CE2 . TRP A 1 144 ? 1.219 -12.936 -52.291 1.00 46.26 ? 140 TRP A CE2 1 ATOM 1099 C CE3 . TRP A 1 144 ? 3.446 -13.688 -52.851 1.00 40.24 ? 140 TRP A CE3 1 ATOM 1100 C CZ2 . TRP A 1 144 ? 1.661 -12.357 -51.105 1.00 64.76 ? 140 TRP A CZ2 1 ATOM 1101 C CZ3 . TRP A 1 144 ? 3.882 -13.112 -51.672 1.00 47.85 ? 140 TRP A CZ3 1 ATOM 1102 C CH2 . TRP A 1 144 ? 2.993 -12.455 -50.814 1.00 62.96 ? 140 TRP A CH2 1 ATOM 1103 N N . LEU A 1 145 ? 4.540 -14.678 -57.064 1.00 46.37 ? 141 LEU A N 1 ATOM 1104 C CA . LEU A 1 145 ? 5.612 -15.282 -57.843 1.00 43.54 ? 141 LEU A CA 1 ATOM 1105 C C . LEU A 1 145 ? 6.632 -15.921 -56.912 1.00 40.74 ? 141 LEU A C 1 ATOM 1106 O O . LEU A 1 145 ? 7.003 -15.323 -55.907 1.00 51.85 ? 141 LEU A O 1 ATOM 1107 C CB . LEU A 1 145 ? 6.277 -14.225 -58.723 1.00 35.77 ? 141 LEU A CB 1 ATOM 1108 C CG . LEU A 1 145 ? 7.436 -14.690 -59.598 1.00 41.18 ? 141 LEU A CG 1 ATOM 1109 C CD1 . LEU A 1 145 ? 6.949 -15.689 -60.647 1.00 51.37 ? 141 LEU A CD1 1 ATOM 1110 C CD2 . LEU A 1 145 ? 8.115 -13.488 -60.242 1.00 40.11 ? 141 LEU A CD2 1 ATOM 1111 N N . ASP A 1 146 ? 7.077 -17.131 -57.238 1.00 52.10 ? 142 ASP A N 1 ATOM 1112 C CA . ASP A 1 146 ? 8.104 -17.794 -56.437 1.00 57.24 ? 142 ASP A CA 1 ATOM 1113 C C . ASP A 1 146 ? 9.466 -17.752 -57.130 1.00 46.48 ? 142 ASP A C 1 ATOM 1114 O O . ASP A 1 146 ? 9.598 -17.229 -58.238 1.00 46.80 ? 142 ASP A O 1 ATOM 1115 C CB . ASP A 1 146 ? 7.707 -19.244 -56.124 1.00 50.33 ? 142 ASP A CB 1 ATOM 1116 C CG . ASP A 1 146 ? 7.426 -20.066 -57.365 1.00 51.10 ? 142 ASP A CG 1 ATOM 1117 O OD1 . ASP A 1 146 ? 7.913 -19.716 -58.461 1.00 46.35 ? 142 ASP A OD1 1 ATOM 1118 O OD2 . ASP A 1 146 ? 6.715 -21.084 -57.235 1.00 59.25 ? 142 ASP A OD2 1 ATOM 1119 N N . SER A 1 147 ? 10.475 -18.306 -56.466 1.00 44.66 ? 143 SER A N 1 ATOM 1120 C CA . SER A 1 147 ? 11.833 -18.329 -57.000 1.00 57.78 ? 143 SER A CA 1 ATOM 1121 C C . SER A 1 147 ? 11.982 -19.346 -58.126 1.00 51.82 ? 143 SER A C 1 ATOM 1122 O O . SER A 1 147 ? 12.911 -19.262 -58.932 1.00 49.52 ? 143 SER A O 1 ATOM 1123 C CB . SER A 1 147 ? 12.832 -18.637 -55.883 1.00 61.72 ? 143 SER A CB 1 ATOM 1124 O OG . SER A 1 147 ? 12.287 -19.555 -54.952 1.00 60.65 ? 143 SER A OG 1 ATOM 1125 N N . GLU A 1 148 ? 11.058 -20.299 -58.182 1.00 49.26 ? 144 GLU A N 1 ATOM 1126 C CA . GLU A 1 148 ? 11.109 -21.362 -59.179 1.00 37.69 ? 144 GLU A CA 1 ATOM 1127 C C . GLU A 1 148 ? 10.425 -20.928 -60.475 1.00 39.42 ? 144 GLU A C 1 ATOM 1128 O O . GLU A 1 148 ? 10.517 -21.615 -61.494 1.00 25.29 ? 144 GLU A O 1 ATOM 1129 C CB . GLU A 1 148 ? 10.463 -22.635 -58.627 1.00 48.71 ? 144 GLU A CB 1 ATOM 1130 C CG . GLU A 1 148 ? 10.911 -22.978 -57.210 1.00 56.70 ? 144 GLU A CG 1 ATOM 1131 C CD . GLU A 1 148 ? 12.418 -23.091 -57.085 1.00 70.96 ? 144 GLU A CD 1 ATOM 1132 O OE1 . GLU A 1 148 ? 13.070 -23.514 -58.063 1.00 70.38 ? 144 GLU A OE1 1 ATOM 1133 O OE2 . GLU A 1 148 ? 12.951 -22.752 -56.007 1.00 84.96 ? 144 GLU A OE2 1 ATOM 1134 N N . GLY A 1 149 ? 9.745 -19.785 -60.430 1.00 53.24 ? 145 GLY A N 1 ATOM 1135 C CA . GLY A 1 149 ? 9.179 -19.183 -61.624 1.00 56.59 ? 145 GLY A CA 1 ATOM 1136 C C . GLY A 1 149 ? 7.729 -19.547 -61.885 1.00 51.86 ? 145 GLY A C 1 ATOM 1137 O O . GLY A 1 149 ? 7.257 -19.429 -63.016 1.00 53.06 ? 145 GLY A O 1 ATOM 1138 N N . ARG A 1 150 ? 7.021 -19.999 -60.853 1.00 41.91 ? 146 ARG A N 1 ATOM 1139 C CA . ARG A 1 150 ? 5.598 -20.292 -60.995 1.00 59.92 ? 146 ARG A CA 1 ATOM 1140 C C . ARG A 1 150 ? 4.749 -19.111 -60.547 1.00 58.58 ? 146 ARG A C 1 ATOM 1141 O O . ARG A 1 150 ? 4.780 -18.710 -59.383 1.00 52.08 ? 146 ARG A O 1 ATOM 1142 C CB . ARG A 1 150 ? 5.195 -21.536 -60.202 1.00 65.10 ? 146 ARG A CB 1 ATOM 1143 C CG . ARG A 1 150 ? 3.706 -21.825 -60.299 1.00 71.07 ? 146 ARG A CG 1 ATOM 1144 C CD . ARG A 1 150 ? 3.369 -23.253 -59.925 1.00 85.15 ? 146 ARG A CD 1 ATOM 1145 N NE . ARG A 1 150 ? 1.940 -23.518 -60.070 1.00 93.17 ? 146 ARG A NE 1 ATOM 1146 C CZ . ARG A 1 150 ? 1.333 -23.752 -61.230 1.00 100.15 ? 146 ARG A CZ 1 ATOM 1147 N NH1 . ARG A 1 150 ? 2.024 -23.755 -62.363 1.00 110.33 ? 146 ARG A NH1 1 ATOM 1148 N NH2 . ARG A 1 150 ? 0.028 -23.981 -61.260 1.00 99.31 ? 146 ARG A NH2 1 ATOM 1149 N N . ASN A 1 151 ? 3.990 -18.561 -61.488 1.00 51.94 ? 147 ASN A N 1 ATOM 1150 C CA . ASN A 1 151 ? 3.052 -17.491 -61.192 1.00 48.30 ? 147 ASN A CA 1 ATOM 1151 C C . ASN A 1 151 ? 1.781 -18.048 -60.561 1.00 46.29 ? 147 ASN A C 1 ATOM 1152 O O . ASN A 1 151 ? 1.145 -18.939 -61.124 1.00 61.99 ? 147 ASN A O 1 ATOM 1153 C CB . ASN A 1 151 ? 2.708 -16.721 -62.468 1.00 55.42 ? 147 ASN A CB 1 ATOM 1154 C CG . ASN A 1 151 ? 3.935 -16.350 -63.276 1.00 68.41 ? 147 ASN A CG 1 ATOM 1155 O OD1 . ASN A 1 151 ? 4.596 -17.216 -63.852 1.00 62.20 ? 147 ASN A OD1 1 ATOM 1156 N ND2 . ASN A 1 151 ? 4.237 -15.057 -63.339 1.00 72.11 ? 147 ASN A ND2 1 ATOM 1157 N N . TYR A 1 152 ? 1.427 -17.534 -59.387 1.00 41.47 ? 148 TYR A N 1 ATOM 1158 C CA . TYR A 1 152 ? 0.156 -17.868 -58.756 1.00 48.00 ? 148 TYR A CA 1 ATOM 1159 C C . TYR A 1 152 ? -0.799 -16.697 -58.950 1.00 48.35 ? 148 TYR A C 1 ATOM 1160 O O . TYR A 1 152 ? -0.630 -15.638 -58.346 1.00 48.60 ? 148 TYR A O 1 ATOM 1161 C CB . TYR A 1 152 ? 0.347 -18.181 -57.271 1.00 43.38 ? 148 TYR A CB 1 ATOM 1162 C CG . TYR A 1 152 ? 1.431 -19.202 -57.004 1.00 52.67 ? 148 TYR A CG 1 ATOM 1163 C CD1 . TYR A 1 152 ? 2.748 -18.810 -56.818 1.00 62.25 ? 148 TYR A CD1 1 ATOM 1164 C CD2 . TYR A 1 152 ? 1.140 -20.557 -56.943 1.00 56.47 ? 148 TYR A CD2 1 ATOM 1165 C CE1 . TYR A 1 152 ? 3.744 -19.736 -56.577 1.00 57.61 ? 148 TYR A CE1 1 ATOM 1166 C CE2 . TYR A 1 152 ? 2.131 -21.491 -56.702 1.00 62.26 ? 148 TYR A CE2 1 ATOM 1167 C CZ . TYR A 1 152 ? 3.431 -21.074 -56.519 1.00 63.13 ? 148 TYR A CZ 1 ATOM 1168 O OH . TYR A 1 152 ? 4.420 -22.001 -56.279 1.00 76.11 ? 148 TYR A OH 1 ATOM 1169 N N . TYR A 1 153 ? -1.801 -16.896 -59.799 1.00 44.44 ? 149 TYR A N 1 ATOM 1170 C CA . TYR A 1 153 ? -2.710 -15.821 -60.176 1.00 56.43 ? 149 TYR A CA 1 ATOM 1171 C C . TYR A 1 153 ? -3.889 -15.733 -59.209 1.00 69.39 ? 149 TYR A C 1 ATOM 1172 O O . TYR A 1 153 ? -4.379 -16.758 -58.732 1.00 78.18 ? 149 TYR A O 1 ATOM 1173 C CB . TYR A 1 153 ? -3.208 -16.035 -61.607 1.00 57.29 ? 149 TYR A CB 1 ATOM 1174 C CG . TYR A 1 153 ? -2.089 -16.114 -62.624 1.00 60.37 ? 149 TYR A CG 1 ATOM 1175 C CD1 . TYR A 1 153 ? -1.041 -15.207 -62.602 1.00 63.98 ? 149 TYR A CD1 1 ATOM 1176 C CD2 . TYR A 1 153 ? -2.073 -17.105 -63.595 1.00 68.04 ? 149 TYR A CD2 1 ATOM 1177 C CE1 . TYR A 1 153 ? -0.016 -15.277 -63.525 1.00 68.20 ? 149 TYR A CE1 1 ATOM 1178 C CE2 . TYR A 1 153 ? -1.049 -17.183 -64.519 1.00 63.08 ? 149 TYR A CE2 1 ATOM 1179 C CZ . TYR A 1 153 ? -0.024 -16.267 -64.479 1.00 64.54 ? 149 TYR A CZ 1 ATOM 1180 O OH . TYR A 1 153 ? 0.998 -16.340 -65.397 1.00 65.17 ? 149 TYR A OH 1 ATOM 1181 N N . PRO A 1 154 ? -4.348 -14.506 -58.909 1.00 66.53 ? 150 PRO A N 1 ATOM 1182 C CA . PRO A 1 154 ? -5.501 -14.357 -58.018 1.00 63.18 ? 150 PRO A CA 1 ATOM 1183 C C . PRO A 1 154 ? -6.793 -14.734 -58.724 1.00 67.89 ? 150 PRO A C 1 ATOM 1184 O O . PRO A 1 154 ? -6.916 -14.524 -59.931 1.00 65.69 ? 150 PRO A O 1 ATOM 1185 C CB . PRO A 1 154 ? -5.476 -12.874 -57.655 1.00 61.50 ? 150 PRO A CB 1 ATOM 1186 C CG . PRO A 1 154 ? -4.857 -12.216 -58.839 1.00 64.10 ? 150 PRO A CG 1 ATOM 1187 C CD . PRO A 1 154 ? -3.869 -13.205 -59.409 1.00 68.50 ? 150 PRO A CD 1 ATOM 1188 N N . ASN A 1 155 ? -7.735 -15.298 -57.978 1.00 80.43 ? 151 ASN A N 1 ATOM 1189 C CA . ASN A 1 155 ? -8.982 -15.775 -58.556 1.00 93.79 ? 151 ASN A CA 1 ATOM 1190 C C . ASN A 1 155 ? -10.126 -15.747 -57.554 1.00 105.22 ? 151 ASN A C 1 ATOM 1191 O O . ASN A 1 155 ? -9.913 -15.919 -56.353 1.00 96.76 ? 151 ASN A O 1 ATOM 1192 C CB . ASN A 1 155 ? -8.798 -17.200 -59.084 1.00 97.91 ? 151 ASN A CB 1 ATOM 1193 C CG . ASN A 1 155 ? -8.456 -18.190 -57.982 1.00 96.74 ? 151 ASN A CG 1 ATOM 1194 O OD1 . ASN A 1 155 ? -7.816 -17.834 -56.993 1.00 84.13 ? 151 ASN A OD1 1 ATOM 1195 N ND2 . ASN A 1 155 ? -8.882 -19.438 -58.149 1.00 100.77 ? 151 ASN A ND2 1 ATOM 1196 N N . ASN A 1 156 ? -11.339 -15.520 -58.049 1.00 114.93 ? 152 ASN A N 1 ATOM 1197 C CA . ASN A 1 156 ? -12.524 -15.854 -57.279 1.00 123.46 ? 152 ASN A CA 1 ATOM 1198 C C . ASN A 1 156 ? -12.419 -17.344 -57.017 1.00 116.96 ? 152 ASN A C 1 ATOM 1199 O O . ASN A 1 156 ? -11.985 -18.087 -57.900 1.00 120.05 ? 152 ASN A O 1 ATOM 1200 C CB . ASN A 1 156 ? -13.811 -15.505 -58.033 1.00 129.78 ? 152 ASN A CB 1 ATOM 1201 C CG . ASN A 1 156 ? -14.012 -16.353 -59.280 1.00 133.43 ? 152 ASN A CG 1 ATOM 1202 O OD1 . ASN A 1 156 ? -13.059 -16.668 -59.992 1.00 134.51 ? 152 ASN A OD1 1 ATOM 1203 N ND2 . ASN A 1 156 ? -15.259 -16.725 -59.548 1.00 135.49 ? 152 ASN A ND2 1 ATOM 1204 N N . ALA A 1 157 ? -12.796 -17.808 -55.831 1.00 119.57 ? 153 ALA A N 1 ATOM 1205 C CA . ALA A 1 157 ? -12.559 -19.210 -55.544 1.00 124.02 ? 153 ALA A CA 1 ATOM 1206 C C . ALA A 1 157 ? -13.774 -20.007 -55.977 1.00 128.21 ? 153 ALA A C 1 ATOM 1207 O O . ALA A 1 157 ? -14.770 -20.092 -55.265 1.00 127.57 ? 153 ALA A O 1 ATOM 1208 C CB . ALA A 1 157 ? -12.278 -19.411 -54.057 1.00 109.27 ? 153 ALA A CB 1 ATOM 1209 N N . ALA A 1 158 ? -13.658 -20.609 -57.157 1.00 126.84 ? 154 ALA A N 1 ATOM 1210 C CA . ALA A 1 158 ? -14.599 -21.610 -57.629 1.00 120.80 ? 154 ALA A CA 1 ATOM 1211 C C . ALA A 1 158 ? -14.155 -22.954 -57.089 1.00 131.42 ? 154 ALA A C 1 ATOM 1212 O O . ALA A 1 158 ? -14.958 -23.761 -56.619 1.00 130.16 ? 154 ALA A O 1 ATOM 1213 C CB . ALA A 1 158 ? -14.661 -21.621 -59.146 1.00 126.73 ? 154 ALA A CB 1 ATOM 1214 N N . GLU A 1 159 ? -12.844 -23.167 -57.168 1.00 138.06 ? 155 GLU A N 1 ATOM 1215 C CA . GLU A 1 159 ? -12.209 -24.378 -56.680 1.00 152.53 ? 155 GLU A CA 1 ATOM 1216 C C . GLU A 1 159 ? -11.186 -24.021 -55.613 1.00 127.15 ? 155 GLU A C 1 ATOM 1217 O O . GLU A 1 159 ? -10.152 -23.417 -55.903 1.00 115.42 ? 155 GLU A O 1 ATOM 1218 C CB . GLU A 1 159 ? -11.542 -25.137 -57.830 1.00 133.33 ? 155 GLU A CB 1 ATOM 1219 C CG . GLU A 1 159 ? -11.003 -26.503 -57.441 1.00 120.67 ? 155 GLU A CG 1 ATOM 1220 C CD . GLU A 1 159 ? -12.084 -27.421 -56.911 1.00 122.99 ? 155 GLU A CD 1 ATOM 1221 O OE1 . GLU A 1 159 ? -12.336 -27.396 -55.688 1.00 133.17 ? 155 GLU A OE1 1 ATOM 1222 O OE2 . GLU A 1 159 ? -12.685 -28.162 -57.716 1.00 110.76 -1 155 GLU A OE2 1 ATOM 1223 N N . THR A 1 160 ? -11.486 -24.402 -54.377 1.00 121.15 ? 156 THR A N 1 ATOM 1224 C CA . THR A 1 160 ? -10.590 -24.166 -53.256 1.00 110.12 ? 156 THR A CA 1 ATOM 1225 C C . THR A 1 160 ? -9.647 -25.349 -53.078 1.00 115.35 ? 156 THR A C 1 ATOM 1226 O O . THR A 1 160 ? -8.772 -25.336 -52.211 1.00 102.91 ? 156 THR A O 1 ATOM 1227 C CB . THR A 1 160 ? -11.372 -23.933 -51.958 1.00 101.58 ? 156 THR A CB 1 ATOM 1228 O OG1 . THR A 1 160 ? -12.226 -25.055 -51.700 1.00 112.62 ? 156 THR A OG1 1 ATOM 1229 C CG2 . THR A 1 160 ? -12.212 -22.666 -52.062 1.00 106.71 ? 156 THR A CG2 1 ATOM 1230 N N . ASP A 1 161 ? -9.831 -26.371 -53.909 1.00 123.59 ? 157 ASP A N 1 ATOM 1231 C CA . ASP A 1 161 ? -8.990 -27.554 -53.855 1.00 116.84 ? 157 ASP A CA 1 ATOM 1232 C C . ASP A 1 161 ? -7.676 -27.290 -54.571 1.00 120.57 ? 157 ASP A C 1 ATOM 1233 O O . ASP A 1 161 ? -7.647 -27.024 -55.773 1.00 122.08 ? 157 ASP A O 1 ATOM 1234 C CB . ASP A 1 161 ? -9.705 -28.750 -54.483 1.00 104.86 ? 157 ASP A CB 1 ATOM 1235 C CG . ASP A 1 161 ? -10.952 -29.151 -53.718 1.00 103.29 ? 157 ASP A CG 1 ATOM 1236 O OD1 . ASP A 1 161 ? -11.059 -28.801 -52.524 1.00 99.87 ? 157 ASP A OD1 1 ATOM 1237 O OD2 . ASP A 1 161 ? -11.824 -29.819 -54.312 1.00 101.13 -1 157 ASP A OD2 1 ATOM 1238 N N . GLY A 1 162 ? -6.589 -27.368 -53.815 1.00 116.52 ? 158 GLY A N 1 ATOM 1239 C CA . GLY A 1 162 ? -5.260 -27.164 -54.350 1.00 107.53 ? 158 GLY A CA 1 ATOM 1240 C C . GLY A 1 162 ? -4.290 -26.908 -53.218 1.00 87.02 ? 158 GLY A C 1 ATOM 1241 O O . GLY A 1 162 ? -4.703 -26.625 -52.095 1.00 88.90 ? 158 GLY A O 1 ATOM 1242 N N . LYS A 1 163 ? -2.999 -26.992 -53.515 1.00 73.10 ? 159 LYS A N 1 ATOM 1243 C CA . LYS A 1 163 ? -1.971 -26.735 -52.518 1.00 72.16 ? 159 LYS A CA 1 ATOM 1244 C C . LYS A 1 163 ? -1.841 -25.234 -52.289 1.00 76.48 ? 159 LYS A C 1 ATOM 1245 O O . LYS A 1 163 ? -1.781 -24.768 -51.149 1.00 68.06 ? 159 LYS A O 1 ATOM 1246 C CB . LYS A 1 163 ? -0.634 -27.330 -52.966 1.00 73.95 ? 159 LYS A CB 1 ATOM 1247 C CG . LYS A 1 163 ? 0.513 -27.125 -51.989 1.00 77.23 ? 159 LYS A CG 1 ATOM 1248 C CD . LYS A 1 163 ? 0.262 -27.826 -50.664 1.00 72.24 ? 159 LYS A CD 1 ATOM 1249 C CE . LYS A 1 163 ? 1.563 -28.038 -49.905 1.00 79.84 ? 159 LYS A CE 1 ATOM 1250 N NZ . LYS A 1 163 ? 2.293 -26.762 -49.686 1.00 70.06 ? 159 LYS A NZ 1 ATOM 1251 N N . TYR A 1 164 ? -1.810 -24.490 -53.391 1.00 79.38 ? 160 TYR A N 1 ATOM 1252 C CA . TYR A 1 164 ? -1.658 -23.040 -53.359 1.00 65.21 ? 160 TYR A CA 1 ATOM 1253 C C . TYR A 1 164 ? -2.938 -22.350 -53.802 1.00 69.85 ? 160 TYR A C 1 ATOM 1254 O O . TYR A 1 164 ? -3.539 -22.725 -54.811 1.00 69.18 ? 160 TYR A O 1 ATOM 1255 C CB . TYR A 1 164 ? -0.504 -22.599 -54.258 1.00 72.14 ? 160 TYR A CB 1 ATOM 1256 C CG . TYR A 1 164 ? 0.855 -23.070 -53.793 1.00 71.29 ? 160 TYR A CG 1 ATOM 1257 C CD1 . TYR A 1 164 ? 1.551 -22.379 -52.813 1.00 70.95 ? 160 TYR A CD1 1 ATOM 1258 C CD2 . TYR A 1 164 ? 1.444 -24.203 -54.337 1.00 60.71 ? 160 TYR A CD2 1 ATOM 1259 C CE1 . TYR A 1 164 ? 2.793 -22.803 -52.383 1.00 77.98 ? 160 TYR A CE1 1 ATOM 1260 C CE2 . TYR A 1 164 ? 2.686 -24.634 -53.914 1.00 67.58 ? 160 TYR A CE2 1 ATOM 1261 C CZ . TYR A 1 164 ? 3.356 -23.931 -52.936 1.00 72.02 ? 160 TYR A CZ 1 ATOM 1262 O OH . TYR A 1 164 ? 4.595 -24.355 -52.512 1.00 60.30 ? 160 TYR A OH 1 ATOM 1263 N N . LEU A 1 165 ? -3.349 -21.341 -53.042 1.00 70.46 ? 161 LEU A N 1 ATOM 1264 C CA . LEU A 1 165 ? -4.503 -20.528 -53.401 1.00 57.60 ? 161 LEU A CA 1 ATOM 1265 C C . LEU A 1 165 ? -4.221 -19.055 -53.154 1.00 49.10 ? 161 LEU A C 1 ATOM 1266 O O . LEU A 1 165 ? -3.877 -18.660 -52.039 1.00 46.59 ? 161 LEU A O 1 ATOM 1267 C CB . LEU A 1 165 ? -5.738 -20.961 -52.608 1.00 58.87 ? 161 LEU A CB 1 ATOM 1268 C CG . LEU A 1 165 ? -6.939 -20.012 -52.685 1.00 50.15 ? 161 LEU A CG 1 ATOM 1269 C CD1 . LEU A 1 165 ? -7.402 -19.836 -54.132 1.00 64.52 ? 161 LEU A CD1 1 ATOM 1270 C CD2 . LEU A 1 165 ? -8.072 -20.508 -51.799 1.00 49.60 ? 161 LEU A CD2 1 ATOM 1271 N N . VAL A 1 166 ? -4.375 -18.245 -54.197 1.00 60.13 ? 162 VAL A N 1 ATOM 1272 C CA . VAL A 1 166 ? -4.336 -16.797 -54.041 1.00 58.96 ? 162 VAL A CA 1 ATOM 1273 C C . VAL A 1 166 ? -5.767 -16.307 -53.869 1.00 49.77 ? 162 VAL A C 1 ATOM 1274 O O . VAL A 1 166 ? -6.567 -16.336 -54.803 1.00 47.77 ? 162 VAL A O 1 ATOM 1275 C CB . VAL A 1 166 ? -3.682 -16.094 -55.240 1.00 51.94 ? 162 VAL A CB 1 ATOM 1276 C CG1 . VAL A 1 166 ? -3.598 -14.586 -54.986 1.00 46.05 ? 162 VAL A CG1 1 ATOM 1277 C CG2 . VAL A 1 166 ? -2.303 -16.673 -55.502 1.00 56.98 ? 162 VAL A CG2 1 ATOM 1278 N N . LEU A 1 167 ? -6.070 -15.853 -52.660 1.00 39.16 ? 163 LEU A N 1 ATOM 1279 C CA . LEU A 1 167 ? -7.423 -15.466 -52.291 1.00 51.26 ? 163 LEU A CA 1 ATOM 1280 C C . LEU A 1 167 ? -7.653 -13.978 -52.580 1.00 63.19 ? 163 LEU A C 1 ATOM 1281 O O . LEU A 1 167 ? -6.698 -13.205 -52.651 1.00 61.70 ? 163 LEU A O 1 ATOM 1282 C CB . LEU A 1 167 ? -7.675 -15.803 -50.815 1.00 54.24 ? 163 LEU A CB 1 ATOM 1283 C CG . LEU A 1 167 ? -6.634 -15.368 -49.783 1.00 45.78 ? 163 LEU A CG 1 ATOM 1284 C CD1 . LEU A 1 167 ? -6.885 -13.936 -49.356 1.00 61.20 ? 163 LEU A CD1 1 ATOM 1285 C CD2 . LEU A 1 167 ? -6.643 -16.311 -48.589 1.00 31.89 ? 163 LEU A CD2 1 ATOM 1286 N N . PRO A 1 168 ? -8.923 -13.573 -52.754 1.00 76.00 ? 164 PRO A N 1 ATOM 1287 C CA . PRO A 1 168 ? -9.245 -12.202 -53.179 1.00 71.84 ? 164 PRO A CA 1 ATOM 1288 C C . PRO A 1 168 ? -8.762 -11.097 -52.235 1.00 67.48 ? 164 PRO A C 1 ATOM 1289 O O . PRO A 1 168 ? -8.547 -9.976 -52.699 1.00 72.80 ? 164 PRO A O 1 ATOM 1290 C CB . PRO A 1 168 ? -10.780 -12.207 -53.253 1.00 58.94 ? 164 PRO A CB 1 ATOM 1291 C CG . PRO A 1 168 ? -11.216 -13.401 -52.467 1.00 48.58 ? 164 PRO A CG 1 ATOM 1292 C CD . PRO A 1 168 ? -10.132 -14.405 -52.633 1.00 55.03 ? 164 PRO A CD 1 ATOM 1293 N N . SER A 1 169 ? -8.582 -11.394 -50.951 1.00 60.94 ? 165 SER A N 1 ATOM 1294 C CA . SER A 1 169 ? -8.138 -10.366 -50.008 1.00 65.77 ? 165 SER A CA 1 ATOM 1295 C C . SER A 1 169 ? -6.667 -10.010 -50.254 1.00 65.20 ? 165 SER A C 1 ATOM 1296 O O . SER A 1 169 ? -6.135 -9.083 -49.641 1.00 59.86 ? 165 SER A O 1 ATOM 1297 C CB . SER A 1 169 ? -8.352 -10.818 -48.558 1.00 53.90 ? 165 SER A CB 1 ATOM 1298 O OG . SER A 1 169 ? -7.200 -11.435 -48.020 1.00 48.21 ? 165 SER A OG 1 ATOM 1299 N N . GLY A 1 170 ? -6.023 -10.754 -51.153 1.00 61.92 ? 166 GLY A N 1 ATOM 1300 C CA . GLY A 1 170 ? -4.701 -10.408 -51.649 1.00 58.88 ? 166 GLY A CA 1 ATOM 1301 C C . GLY A 1 170 ? -3.564 -11.274 -51.137 1.00 48.60 ? 166 GLY A C 1 ATOM 1302 O O . GLY A 1 170 ? -2.411 -11.066 -51.518 1.00 55.55 ? 166 GLY A O 1 ATOM 1303 N N . GLU A 1 171 ? -3.874 -12.254 -50.291 1.00 49.77 ? 167 GLU A N 1 ATOM 1304 C CA . GLU A 1 171 ? -2.835 -13.099 -49.703 1.00 52.89 ? 167 GLU A CA 1 ATOM 1305 C C . GLU A 1 171 ? -2.579 -14.371 -50.507 1.00 51.65 ? 167 GLU A C 1 ATOM 1306 O O . GLU A 1 171 ? -3.240 -14.636 -51.513 1.00 40.35 ? 167 GLU A O 1 ATOM 1307 C CB . GLU A 1 171 ? -3.201 -13.483 -48.265 1.00 45.17 ? 167 GLU A CB 1 ATOM 1308 C CG . GLU A 1 171 ? -2.940 -12.394 -47.237 1.00 66.42 ? 167 GLU A CG 1 ATOM 1309 C CD . GLU A 1 171 ? -3.958 -11.278 -47.292 1.00 69.56 ? 167 GLU A CD 1 ATOM 1310 O OE1 . GLU A 1 171 ? -4.702 -11.199 -48.291 1.00 62.43 ? 167 GLU A OE1 1 ATOM 1311 O OE2 . GLU A 1 171 ? -4.017 -10.481 -46.333 1.00 76.77 ? 167 GLU A OE2 1 ATOM 1312 N N . LEU A 1 172 ? -1.602 -15.146 -50.041 1.00 62.63 ? 168 LEU A N 1 ATOM 1313 C CA . LEU A 1 172 ? -1.269 -16.443 -50.617 1.00 52.40 ? 168 LEU A CA 1 ATOM 1314 C C . LEU A 1 172 ? -1.423 -17.517 -49.546 1.00 52.80 ? 168 LEU A C 1 ATOM 1315 O O . LEU A 1 172 ? -0.672 -17.542 -48.569 1.00 52.05 ? 168 LEU A O 1 ATOM 1316 C CB . LEU A 1 172 ? 0.157 -16.442 -51.172 1.00 46.30 ? 168 LEU A CB 1 ATOM 1317 C CG . LEU A 1 172 ? 0.640 -17.743 -51.816 1.00 33.94 ? 168 LEU A CG 1 ATOM 1318 C CD1 . LEU A 1 172 ? -0.122 -18.033 -53.108 1.00 37.29 ? 168 LEU A CD1 1 ATOM 1319 C CD2 . LEU A 1 172 ? 2.142 -17.680 -52.067 1.00 51.13 ? 168 LEU A CD2 1 ATOM 1320 N N . HIS A 1 173 ? -2.399 -18.398 -49.734 1.00 64.83 ? 169 HIS A N 1 ATOM 1321 C CA . HIS A 1 173 ? -2.672 -19.455 -48.770 1.00 51.99 ? 169 HIS A CA 1 ATOM 1322 C C . HIS A 1 173 ? -1.980 -20.744 -49.189 1.00 53.51 ? 169 HIS A C 1 ATOM 1323 O O . HIS A 1 173 ? -2.102 -21.179 -50.335 1.00 61.87 ? 169 HIS A O 1 ATOM 1324 C CB . HIS A 1 173 ? -4.177 -19.689 -48.628 1.00 51.20 ? 169 HIS A CB 1 ATOM 1325 C CG . HIS A 1 173 ? -4.530 -20.662 -47.547 1.00 55.36 ? 169 HIS A CG 1 ATOM 1326 N ND1 . HIS A 1 173 ? -4.493 -22.027 -47.732 1.00 45.43 ? 169 HIS A ND1 1 ATOM 1327 C CD2 . HIS A 1 173 ? -4.916 -20.466 -46.264 1.00 51.96 ? 169 HIS A CD2 1 ATOM 1328 C CE1 . HIS A 1 173 ? -4.844 -22.630 -46.610 1.00 55.32 ? 169 HIS A CE1 1 ATOM 1329 N NE2 . HIS A 1 173 ? -5.106 -21.705 -45.704 1.00 53.06 ? 169 HIS A NE2 1 ATOM 1330 N N . ILE A 1 174 ? -1.252 -21.348 -48.255 1.00 44.72 ? 170 ILE A N 1 ATOM 1331 C CA . ILE A 1 174 ? -0.544 -22.596 -48.515 1.00 51.13 ? 170 ILE A CA 1 ATOM 1332 C C . ILE A 1 174 ? -0.974 -23.651 -47.502 1.00 46.48 ? 170 ILE A C 1 ATOM 1333 O O . ILE A 1 174 ? -0.884 -23.444 -46.291 1.00 40.83 ? 170 ILE A O 1 ATOM 1334 C CB . ILE A 1 174 ? 0.984 -22.401 -48.462 1.00 68.26 ? 170 ILE A CB 1 ATOM 1335 C CG1 . ILE A 1 174 ? 1.390 -21.228 -49.361 1.00 54.52 ? 170 ILE A CG1 1 ATOM 1336 C CG2 . ILE A 1 174 ? 1.699 -23.686 -48.881 1.00 63.48 ? 170 ILE A CG2 1 ATOM 1337 C CD1 . ILE A 1 174 ? 2.861 -20.874 -49.309 1.00 41.30 ? 170 ILE A CD1 1 ATOM 1338 N N . ARG A 1 175 ? -1.448 -24.782 -48.014 1.00 45.98 ? 171 ARG A N 1 ATOM 1339 C CA . ARG A 1 175 ? -1.974 -25.851 -47.177 1.00 61.64 ? 171 ARG A CA 1 ATOM 1340 C C . ARG A 1 175 ? -0.878 -26.727 -46.584 1.00 75.37 ? 171 ARG A C 1 ATOM 1341 O O . ARG A 1 175 ? -0.108 -27.344 -47.320 1.00 68.78 ? 171 ARG A O 1 ATOM 1342 C CB . ARG A 1 175 ? -2.928 -26.730 -47.984 1.00 66.15 ? 171 ARG A CB 1 ATOM 1343 C CG . ARG A 1 175 ? -4.346 -26.219 -48.057 1.00 62.39 ? 171 ARG A CG 1 ATOM 1344 C CD . ARG A 1 175 ? -5.206 -27.195 -48.831 1.00 67.08 ? 171 ARG A CD 1 ATOM 1345 N NE . ARG A 1 175 ? -6.627 -26.869 -48.769 1.00 87.09 ? 171 ARG A NE 1 ATOM 1346 C CZ . ARG A 1 175 ? -7.573 -27.536 -49.421 1.00 79.72 ? 171 ARG A CZ 1 ATOM 1347 N NH1 . ARG A 1 175 ? -7.253 -28.567 -50.193 1.00 93.66 ? 171 ARG A NH1 1 ATOM 1348 N NH2 . ARG A 1 175 ? -8.840 -27.171 -49.303 1.00 66.00 ? 171 ARG A NH2 1 ATOM 1349 N N . GLU A 1 176 ? -0.830 -26.783 -45.255 1.00 71.85 ? 172 GLU A N 1 ATOM 1350 C CA . GLU A 1 176 ? 0.028 -27.727 -44.545 1.00 53.42 ? 172 GLU A CA 1 ATOM 1351 C C . GLU A 1 176 ? 1.463 -27.697 -45.055 1.00 57.52 ? 172 GLU A C 1 ATOM 1352 O O . GLU A 1 176 ? 1.914 -28.627 -45.727 1.00 74.19 ? 172 GLU A O 1 ATOM 1353 C CB . GLU A 1 176 ? -0.542 -29.139 -44.670 1.00 68.24 ? 172 GLU A CB 1 ATOM 1354 C CG . GLU A 1 176 ? -1.938 -29.281 -44.088 1.00 76.35 ? 172 GLU A CG 1 ATOM 1355 C CD . GLU A 1 176 ? -2.576 -30.617 -44.411 1.00 82.41 ? 172 GLU A CD 1 ATOM 1356 O OE1 . GLU A 1 176 ? -1.977 -31.397 -45.181 1.00 82.09 ? 172 GLU A OE1 1 ATOM 1357 O OE2 . GLU A 1 176 ? -3.680 -30.887 -43.893 1.00 83.17 ? 172 GLU A OE2 1 ATOM 1358 N N . VAL A 1 177 ? 2.168 -26.617 -44.740 1.00 62.52 ? 173 VAL A N 1 ATOM 1359 C CA . VAL A 1 177 ? 3.521 -26.403 -45.238 1.00 70.77 ? 173 VAL A CA 1 ATOM 1360 C C . VAL A 1 177 ? 4.453 -27.531 -44.803 1.00 60.40 ? 173 VAL A C 1 ATOM 1361 O O . VAL A 1 177 ? 4.247 -28.163 -43.766 1.00 54.04 ? 173 VAL A O 1 ATOM 1362 C CB . VAL A 1 177 ? 4.081 -25.046 -44.753 1.00 64.53 ? 173 VAL A CB 1 ATOM 1363 C CG1 . VAL A 1 177 ? 5.530 -24.850 -45.205 1.00 71.97 ? 173 VAL A CG1 1 ATOM 1364 C CG2 . VAL A 1 177 ? 3.208 -23.910 -45.266 1.00 51.11 ? 173 VAL A CG2 1 ATOM 1365 N N . GLY A 1 178 ? 5.475 -27.774 -45.617 1.00 62.32 ? 174 GLY A N 1 ATOM 1366 C CA . GLY A 1 178 ? 6.436 -28.832 -45.373 1.00 71.64 ? 174 GLY A CA 1 ATOM 1367 C C . GLY A 1 178 ? 7.781 -28.432 -45.951 1.00 76.76 ? 174 GLY A C 1 ATOM 1368 O O . GLY A 1 178 ? 7.931 -27.317 -46.450 1.00 83.08 ? 174 GLY A O 1 ATOM 1369 N N . PRO A 1 179 ? 8.770 -29.334 -45.881 1.00 72.05 ? 175 PRO A N 1 ATOM 1370 C CA . PRO A 1 179 ? 10.139 -29.018 -46.304 1.00 63.54 ? 175 PRO A CA 1 ATOM 1371 C C . PRO A 1 179 ? 10.229 -28.590 -47.765 1.00 63.10 ? 175 PRO A C 1 ATOM 1372 O O . PRO A 1 179 ? 11.041 -27.727 -48.096 1.00 73.80 ? 175 PRO A O 1 ATOM 1373 C CB . PRO A 1 179 ? 10.888 -30.335 -46.076 1.00 72.98 ? 175 PRO A CB 1 ATOM 1374 C CG . PRO A 1 179 ? 9.834 -31.388 -46.144 1.00 79.82 ? 175 PRO A CG 1 ATOM 1375 C CD . PRO A 1 179 ? 8.607 -30.760 -45.557 1.00 81.13 ? 175 PRO A CD 1 ATOM 1376 N N . GLU A 1 180 ? 9.395 -29.178 -48.619 1.00 64.49 ? 176 GLU A N 1 ATOM 1377 C CA . GLU A 1 180 ? 9.439 -28.896 -50.051 1.00 67.31 ? 176 GLU A CA 1 ATOM 1378 C C . GLU A 1 180 ? 9.143 -27.426 -50.343 1.00 75.87 ? 176 GLU A C 1 ATOM 1379 O O . GLU A 1 180 ? 9.561 -26.890 -51.372 1.00 76.46 ? 176 GLU A O 1 ATOM 1380 C CB . GLU A 1 180 ? 8.447 -29.789 -50.802 1.00 56.22 ? 176 GLU A CB 1 ATOM 1381 C CG . GLU A 1 180 ? 8.451 -29.568 -52.309 1.00 58.95 ? 176 GLU A CG 1 ATOM 1382 C CD . GLU A 1 180 ? 7.811 -30.709 -53.077 1.00 80.21 ? 176 GLU A CD 1 ATOM 1383 O OE1 . GLU A 1 180 ? 7.933 -30.729 -54.320 1.00 89.91 ? 176 GLU A OE1 1 ATOM 1384 O OE2 . GLU A 1 180 ? 7.187 -31.585 -52.441 1.00 98.29 ? 176 GLU A OE2 1 ATOM 1385 N N . ASP A 1 181 ? 8.425 -26.786 -49.427 1.00 77.21 ? 177 ASP A N 1 ATOM 1386 C CA . ASP A 1 181 ? 8.075 -25.376 -49.552 1.00 71.70 ? 177 ASP A CA 1 ATOM 1387 C C . ASP A 1 181 ? 9.070 -24.489 -48.802 1.00 65.76 ? 177 ASP A C 1 ATOM 1388 O O . ASP A 1 181 ? 8.964 -23.262 -48.828 1.00 64.66 ? 177 ASP A O 1 ATOM 1389 C CB . ASP A 1 181 ? 6.658 -25.143 -49.025 1.00 73.52 ? 177 ASP A CB 1 ATOM 1390 C CG . ASP A 1 181 ? 5.681 -26.212 -49.484 1.00 59.73 ? 177 ASP A CG 1 ATOM 1391 O OD1 . ASP A 1 181 ? 5.758 -26.626 -50.660 1.00 60.98 ? 177 ASP A OD1 1 ATOM 1392 O OD2 . ASP A 1 181 ? 4.841 -26.642 -48.665 1.00 51.41 ? 177 ASP A OD2 1 ATOM 1393 N N . GLY A 1 182 ? 10.046 -25.113 -48.148 1.00 69.87 ? 178 GLY A N 1 ATOM 1394 C CA . GLY A 1 182 ? 10.961 -24.400 -47.275 1.00 75.58 ? 178 GLY A CA 1 ATOM 1395 C C . GLY A 1 182 ? 11.965 -23.517 -47.990 1.00 77.01 ? 178 GLY A C 1 ATOM 1396 O O . GLY A 1 182 ? 12.143 -22.355 -47.618 1.00 85.02 ? 178 GLY A O 1 ATOM 1397 N N . TYR A 1 183 ? 12.621 -24.059 -49.012 1.00 61.23 ? 179 TYR A N 1 ATOM 1398 C CA . TYR A 1 183 ? 13.679 -23.333 -49.711 1.00 71.57 ? 179 TYR A CA 1 ATOM 1399 C C . TYR A 1 183 ? 13.148 -22.555 -50.914 1.00 84.54 ? 179 TYR A C 1 ATOM 1400 O O . TYR A 1 183 ? 13.919 -21.944 -51.654 1.00 99.05 ? 179 TYR A O 1 ATOM 1401 C CB . TYR A 1 183 ? 14.787 -24.298 -50.142 1.00 98.80 ? 179 TYR A CB 1 ATOM 1402 C CG . TYR A 1 183 ? 15.820 -24.531 -49.060 1.00 102.38 ? 179 TYR A CG 1 ATOM 1403 C CD1 . TYR A 1 183 ? 15.538 -25.337 -47.966 1.00 96.31 ? 179 TYR A CD1 1 ATOM 1404 C CD2 . TYR A 1 183 ? 17.074 -23.937 -49.129 1.00 102.07 ? 179 TYR A CD2 1 ATOM 1405 C CE1 . TYR A 1 183 ? 16.475 -25.548 -46.974 1.00 101.44 ? 179 TYR A CE1 1 ATOM 1406 C CE2 . TYR A 1 183 ? 18.017 -24.144 -48.142 1.00 111.88 ? 179 TYR A CE2 1 ATOM 1407 C CZ . TYR A 1 183 ? 17.713 -24.949 -47.066 1.00 112.61 ? 179 TYR A CZ 1 ATOM 1408 O OH . TYR A 1 183 ? 18.650 -25.156 -46.081 1.00 129.16 ? 179 TYR A OH 1 ATOM 1409 N N . LYS A 1 184 ? 11.831 -22.578 -51.105 1.00 83.68 ? 180 LYS A N 1 ATOM 1410 C CA . LYS A 1 184 ? 11.184 -21.696 -52.072 1.00 59.82 ? 180 LYS A CA 1 ATOM 1411 C C . LYS A 1 184 ? 10.992 -20.315 -51.449 1.00 66.21 ? 180 LYS A C 1 ATOM 1412 O O . LYS A 1 184 ? 10.719 -20.206 -50.253 1.00 80.16 ? 180 LYS A O 1 ATOM 1413 C CB . LYS A 1 184 ? 9.836 -22.268 -52.518 1.00 53.36 ? 180 LYS A CB 1 ATOM 1414 C CG . LYS A 1 184 ? 9.935 -23.525 -53.367 1.00 82.75 ? 180 LYS A CG 1 ATOM 1415 C CD . LYS A 1 184 ? 8.601 -24.261 -53.426 1.00 73.85 ? 180 LYS A CD 1 ATOM 1416 C CE . LYS A 1 184 ? 7.580 -23.539 -54.295 1.00 78.64 ? 180 LYS A CE 1 ATOM 1417 N NZ . LYS A 1 184 ? 7.861 -23.706 -55.747 1.00 64.63 ? 180 LYS A NZ 1 ATOM 1418 N N . SER A 1 185 ? 11.144 -19.268 -52.258 1.00 65.43 ? 181 SER A N 1 ATOM 1419 C CA . SER A 1 185 ? 10.922 -17.894 -51.805 1.00 60.59 ? 181 SER A CA 1 ATOM 1420 C C . SER A 1 185 ? 9.908 -17.215 -52.720 1.00 60.85 ? 181 SER A C 1 ATOM 1421 O O . SER A 1 185 ? 9.850 -17.520 -53.910 1.00 59.89 ? 181 SER A O 1 ATOM 1422 C CB . SER A 1 185 ? 12.235 -17.110 -51.777 1.00 56.73 ? 181 SER A CB 1 ATOM 1423 O OG . SER A 1 185 ? 12.790 -16.990 -53.073 1.00 50.64 ? 181 SER A OG 1 ATOM 1424 N N . TYR A 1 186 ? 9.123 -16.292 -52.164 1.00 64.46 ? 182 TYR A N 1 ATOM 1425 C CA . TYR A 1 186 ? 7.961 -15.739 -52.862 1.00 54.55 ? 182 TYR A CA 1 ATOM 1426 C C . TYR A 1 186 ? 7.972 -14.215 -52.975 1.00 59.39 ? 182 TYR A C 1 ATOM 1427 O O . TYR A 1 186 ? 8.247 -13.507 -52.006 1.00 64.48 ? 182 TYR A O 1 ATOM 1428 C CB . TYR A 1 186 ? 6.677 -16.178 -52.155 1.00 49.46 ? 182 TYR A CB 1 ATOM 1429 C CG . TYR A 1 186 ? 6.510 -17.679 -52.080 1.00 60.46 ? 182 TYR A CG 1 ATOM 1430 C CD1 . TYR A 1 186 ? 7.025 -18.401 -51.014 1.00 54.98 ? 182 TYR A CD1 1 ATOM 1431 C CD2 . TYR A 1 186 ? 5.845 -18.376 -53.079 1.00 62.93 ? 182 TYR A CD2 1 ATOM 1432 C CE1 . TYR A 1 186 ? 6.879 -19.774 -50.941 1.00 50.23 ? 182 TYR A CE1 1 ATOM 1433 C CE2 . TYR A 1 186 ? 5.695 -19.749 -53.015 1.00 66.51 ? 182 TYR A CE2 1 ATOM 1434 C CZ . TYR A 1 186 ? 6.214 -20.443 -51.944 1.00 65.90 ? 182 TYR A CZ 1 ATOM 1435 O OH . TYR A 1 186 ? 6.066 -21.811 -51.877 1.00 83.30 ? 182 TYR A OH 1 ATOM 1436 N N . GLN A 1 187 ? 7.665 -13.729 -54.176 1.00 57.15 ? 183 GLN A N 1 ATOM 1437 C CA . GLN A 1 187 ? 7.438 -12.311 -54.424 1.00 34.94 ? 183 GLN A CA 1 ATOM 1438 C C . GLN A 1 187 ? 5.967 -12.042 -54.708 1.00 50.22 ? 183 GLN A C 1 ATOM 1439 O O . GLN A 1 187 ? 5.269 -12.893 -55.262 1.00 58.40 ? 183 GLN A O 1 ATOM 1440 C CB . GLN A 1 187 ? 8.268 -11.824 -55.611 1.00 34.49 ? 183 GLN A CB 1 ATOM 1441 C CG . GLN A 1 187 ? 9.767 -11.865 -55.413 1.00 54.29 ? 183 GLN A CG 1 ATOM 1442 C CD . GLN A 1 187 ? 10.501 -11.061 -56.469 1.00 57.64 ? 183 GLN A CD 1 ATOM 1443 O OE1 . GLN A 1 187 ? 10.386 -9.836 -56.521 1.00 51.21 ? 183 GLN A OE1 1 ATOM 1444 N NE2 . GLN A 1 187 ? 11.251 -11.746 -57.324 1.00 57.93 ? 183 GLN A NE2 1 ATOM 1445 N N . CYS A 1 188 ? 5.504 -10.856 -54.325 1.00 58.59 ? 184 CYS A N 1 ATOM 1446 C CA . CYS A 1 188 ? 4.203 -10.357 -54.753 1.00 49.68 ? 184 CYS A CA 1 ATOM 1447 C C . CYS A 1 188 ? 4.422 -9.077 -55.542 1.00 45.18 ? 184 CYS A C 1 ATOM 1448 O O . CYS A 1 188 ? 5.153 -8.190 -55.101 1.00 60.72 ? 184 CYS A O 1 ATOM 1449 C CB . CYS A 1 188 ? 3.279 -10.098 -53.560 1.00 48.10 ? 184 CYS A CB 1 ATOM 1450 S SG . CYS A 1 188 ? 3.838 -8.810 -52.417 1.00 92.03 ? 184 CYS A SG 1 ATOM 1451 N N . ARG A 1 189 ? 3.806 -8.990 -56.716 1.00 43.44 ? 185 ARG A N 1 ATOM 1452 C CA . ARG A 1 189 ? 3.883 -7.779 -57.520 1.00 47.80 ? 185 ARG A CA 1 ATOM 1453 C C . ARG A 1 189 ? 2.538 -7.073 -57.473 1.00 42.85 ? 185 ARG A C 1 ATOM 1454 O O . ARG A 1 189 ? 1.485 -7.709 -57.559 1.00 45.48 ? 185 ARG A O 1 ATOM 1455 C CB . ARG A 1 189 ? 4.296 -8.100 -58.957 1.00 36.92 ? 185 ARG A CB 1 ATOM 1456 C CG . ARG A 1 189 ? 3.173 -8.190 -59.963 1.00 41.24 ? 185 ARG A CG 1 ATOM 1457 C CD . ARG A 1 189 ? 3.743 -8.432 -61.337 1.00 42.32 ? 185 ARG A CD 1 ATOM 1458 N NE . ARG A 1 189 ? 2.724 -8.858 -62.287 1.00 61.10 ? 185 ARG A NE 1 ATOM 1459 C CZ . ARG A 1 189 ? 2.943 -9.013 -63.587 1.00 67.81 ? 185 ARG A CZ 1 ATOM 1460 N NH1 . ARG A 1 189 ? 4.144 -8.767 -64.090 1.00 66.54 ? 185 ARG A NH1 1 ATOM 1461 N NH2 . ARG A 1 189 ? 1.960 -9.407 -64.382 1.00 73.63 ? 185 ARG A NH2 1 ATOM 1462 N N . THR A 1 190 ? 2.588 -5.753 -57.338 1.00 38.97 ? 186 THR A N 1 ATOM 1463 C CA . THR A 1 190 ? 1.396 -4.957 -57.096 1.00 34.44 ? 186 THR A CA 1 ATOM 1464 C C . THR A 1 190 ? 1.125 -4.009 -58.252 1.00 44.51 ? 186 THR A C 1 ATOM 1465 O O . THR A 1 190 ? 2.040 -3.637 -58.987 1.00 41.51 ? 186 THR A O 1 ATOM 1466 C CB . THR A 1 190 ? 1.530 -4.145 -55.803 1.00 39.52 ? 186 THR A CB 1 ATOM 1467 O OG1 . THR A 1 190 ? 2.497 -3.105 -55.989 1.00 51.61 ? 186 THR A OG1 1 ATOM 1468 C CG2 . THR A 1 190 ? 1.959 -5.041 -54.648 1.00 49.16 ? 186 THR A CG2 1 ATOM 1469 N N . LYS A 1 191 ? -0.139 -3.624 -58.399 1.00 44.35 ? 187 LYS A N 1 ATOM 1470 C CA . LYS A 1 191 ? -0.561 -2.737 -59.475 1.00 45.04 ? 187 LYS A CA 1 ATOM 1471 C C . LYS A 1 191 ? -1.267 -1.511 -58.910 1.00 46.93 ? 187 LYS A C 1 ATOM 1472 O O . LYS A 1 191 ? -2.104 -1.626 -58.014 1.00 62.25 ? 187 LYS A O 1 ATOM 1473 C CB . LYS A 1 191 ? -1.481 -3.482 -60.440 1.00 31.26 ? 187 LYS A CB 1 ATOM 1474 C CG . LYS A 1 191 ? -1.430 -2.969 -61.864 1.00 45.94 ? 187 LYS A CG 1 ATOM 1475 C CD . LYS A 1 191 ? -2.349 -3.775 -62.761 1.00 60.93 ? 187 LYS A CD 1 ATOM 1476 C CE . LYS A 1 191 ? -1.827 -3.836 -64.184 1.00 63.26 ? 187 LYS A CE 1 ATOM 1477 N NZ . LYS A 1 191 ? -2.661 -4.719 -65.042 1.00 75.43 ? 187 LYS A NZ 1 ATOM 1478 N N . HIS A 1 192 ? -0.918 -0.339 -59.432 1.00 39.12 ? 188 HIS A N 1 ATOM 1479 C CA . HIS A 1 192 ? -1.574 0.904 -59.044 1.00 45.61 ? 188 HIS A CA 1 ATOM 1480 C C . HIS A 1 192 ? -2.789 1.117 -59.944 1.00 50.72 ? 188 HIS A C 1 ATOM 1481 O O . HIS A 1 192 ? -2.652 1.216 -61.162 1.00 50.11 ? 188 HIS A O 1 ATOM 1482 C CB . HIS A 1 192 ? -0.606 2.084 -59.143 1.00 55.45 ? 188 HIS A CB 1 ATOM 1483 C CG . HIS A 1 192 ? -1.046 3.291 -58.377 1.00 55.01 ? 188 HIS A CG 1 ATOM 1484 N ND1 . HIS A 1 192 ? -0.538 3.613 -57.137 1.00 63.54 ? 188 HIS A ND1 1 ATOM 1485 C CD2 . HIS A 1 192 ? -1.955 4.250 -58.670 1.00 47.07 ? 188 HIS A CD2 1 ATOM 1486 C CE1 . HIS A 1 192 ? -1.111 4.721 -56.702 1.00 51.37 ? 188 HIS A CE1 1 ATOM 1487 N NE2 . HIS A 1 192 ? -1.976 5.128 -57.614 1.00 41.16 ? 188 HIS A NE2 1 ATOM 1488 N N . ARG A 1 193 ? -3.976 1.179 -59.345 1.00 45.49 ? 189 ARG A N 1 ATOM 1489 C CA . ARG A 1 193 ? -5.217 1.173 -60.116 1.00 48.41 ? 189 ARG A CA 1 ATOM 1490 C C . ARG A 1 193 ? -5.421 2.463 -60.910 1.00 37.50 ? 189 ARG A C 1 ATOM 1491 O O . ARG A 1 193 ? -6.266 2.519 -61.804 1.00 46.92 ? 189 ARG A O 1 ATOM 1492 C CB . ARG A 1 193 ? -6.409 0.931 -59.189 1.00 56.84 ? 189 ARG A CB 1 ATOM 1493 C CG . ARG A 1 193 ? -6.703 2.065 -58.235 1.00 61.99 ? 189 ARG A CG 1 ATOM 1494 C CD . ARG A 1 193 ? -7.626 1.612 -57.124 1.00 68.04 ? 189 ARG A CD 1 ATOM 1495 N NE . ARG A 1 193 ? -8.534 2.671 -56.694 1.00 87.87 ? 189 ARG A NE 1 ATOM 1496 C CZ . ARG A 1 193 ? -9.220 2.652 -55.556 1.00 88.31 ? 189 ARG A CZ 1 ATOM 1497 N NH1 . ARG A 1 193 ? -9.096 1.632 -54.717 1.00 82.69 ? 189 ARG A NH1 1 ATOM 1498 N NH2 . ARG A 1 193 ? -10.025 3.660 -55.252 1.00 87.35 ? 189 ARG A NH2 1 ATOM 1499 N N . LEU A 1 194 ? -4.648 3.494 -60.583 1.00 43.98 ? 190 LEU A N 1 ATOM 1500 C CA . LEU A 1 194 ? -4.650 4.738 -61.351 1.00 47.58 ? 190 LEU A CA 1 ATOM 1501 C C . LEU A 1 194 ? -3.646 4.630 -62.493 1.00 53.36 ? 190 LEU A C 1 ATOM 1502 O O . LEU A 1 194 ? -4.012 4.684 -63.668 1.00 52.17 ? 190 LEU A O 1 ATOM 1503 C CB . LEU A 1 194 ? -4.311 5.941 -60.466 1.00 44.42 ? 190 LEU A CB 1 ATOM 1504 C CG . LEU A 1 194 ? -5.056 6.062 -59.137 1.00 51.96 ? 190 LEU A CG 1 ATOM 1505 C CD1 . LEU A 1 194 ? -4.543 7.271 -58.363 1.00 39.89 ? 190 LEU A CD1 1 ATOM 1506 C CD2 . LEU A 1 194 ? -6.561 6.149 -59.366 1.00 40.98 ? 190 LEU A CD2 1 ATOM 1507 N N . THR A 1 195 ? -2.374 4.483 -62.130 1.00 56.33 ? 191 THR A N 1 ATOM 1508 C CA . THR A 1 195 ? -1.291 4.373 -63.101 1.00 57.28 ? 191 THR A CA 1 ATOM 1509 C C . THR A 1 195 ? -1.431 3.114 -63.952 1.00 64.58 ? 191 THR A C 1 ATOM 1510 O O . THR A 1 195 ? -1.394 3.177 -65.181 1.00 63.02 ? 191 THR A O 1 ATOM 1511 C CB . THR A 1 195 ? 0.085 4.352 -62.405 1.00 52.54 ? 191 THR A CB 1 ATOM 1512 O OG1 . THR A 1 195 ? 0.184 5.458 -61.500 1.00 69.09 ? 191 THR A OG1 1 ATOM 1513 C CG2 . THR A 1 195 ? 1.212 4.427 -63.431 1.00 59.94 ? 191 THR A CG2 1 ATOM 1514 N N . GLY A 1 196 ? -1.586 1.973 -63.288 1.00 53.79 ? 192 GLY A N 1 ATOM 1515 C CA . GLY A 1 196 ? -1.710 0.699 -63.971 1.00 54.42 ? 192 GLY A CA 1 ATOM 1516 C C . GLY A 1 196 ? -0.362 0.052 -64.228 1.00 64.83 ? 192 GLY A C 1 ATOM 1517 O O . GLY A 1 196 ? -0.266 -0.899 -65.004 1.00 71.05 ? 192 GLY A O 1 ATOM 1518 N N . GLU A 1 197 ? 0.678 0.567 -63.575 1.00 61.63 ? 193 GLU A N 1 ATOM 1519 C CA . GLU A 1 197 ? 2.024 0.023 -63.725 1.00 52.30 ? 193 GLU A CA 1 ATOM 1520 C C . GLU A 1 197 ? 2.351 -0.957 -62.603 1.00 60.79 ? 193 GLU A C 1 ATOM 1521 O O . GLU A 1 197 ? 2.041 -0.711 -61.436 1.00 49.11 ? 193 GLU A O 1 ATOM 1522 C CB . GLU A 1 197 ? 3.060 1.148 -63.762 1.00 56.67 ? 193 GLU A CB 1 ATOM 1523 C CG . GLU A 1 197 ? 3.194 1.799 -65.128 1.00 64.27 ? 193 GLU A CG 1 ATOM 1524 C CD . GLU A 1 197 ? 4.331 2.799 -65.196 1.00 91.44 ? 193 GLU A CD 1 ATOM 1525 O OE1 . GLU A 1 197 ? 5.026 2.986 -64.175 1.00 97.08 ? 193 GLU A OE1 1 ATOM 1526 O OE2 . GLU A 1 197 ? 4.532 3.395 -66.275 1.00 95.34 ? 193 GLU A OE2 1 ATOM 1527 N N . THR A 1 198 ? 2.988 -2.063 -62.977 1.00 63.38 ? 194 THR A N 1 ATOM 1528 C CA . THR A 1 198 ? 3.282 -3.151 -62.053 1.00 50.11 ? 194 THR A CA 1 ATOM 1529 C C . THR A 1 198 ? 4.685 -3.043 -61.464 1.00 55.68 ? 194 THR A C 1 ATOM 1530 O O . THR A 1 198 ? 5.625 -2.625 -62.143 1.00 46.23 ? 194 THR A O 1 ATOM 1531 C CB . THR A 1 198 ? 3.140 -4.514 -62.747 1.00 57.48 ? 194 THR A CB 1 ATOM 1532 O OG1 . THR A 1 198 ? 3.871 -4.502 -63.981 1.00 71.07 ? 194 THR A OG1 1 ATOM 1533 C CG2 . THR A 1 198 ? 1.675 -4.815 -63.028 1.00 53.05 ? 194 THR A CG2 1 ATOM 1534 N N . ARG A 1 199 ? 4.812 -3.416 -60.193 1.00 48.38 ? 195 ARG A N 1 ATOM 1535 C CA . ARG A 1 199 ? 6.095 -3.382 -59.504 1.00 51.42 ? 195 ARG A CA 1 ATOM 1536 C C . ARG A 1 199 ? 6.267 -4.598 -58.594 1.00 52.32 ? 195 ARG A C 1 ATOM 1537 O O . ARG A 1 199 ? 5.404 -4.890 -57.765 1.00 44.78 ? 195 ARG A O 1 ATOM 1538 C CB . ARG A 1 199 ? 6.220 -2.091 -58.697 1.00 50.65 ? 195 ARG A CB 1 ATOM 1539 C CG . ARG A 1 199 ? 7.645 -1.710 -58.369 1.00 62.98 ? 195 ARG A CG 1 ATOM 1540 C CD . ARG A 1 199 ? 7.715 -0.279 -57.880 1.00 65.02 ? 195 ARG A CD 1 ATOM 1541 N NE . ARG A 1 199 ? 9.078 0.138 -57.572 1.00 76.71 ? 195 ARG A NE 1 ATOM 1542 C CZ . ARG A 1 199 ? 9.400 1.327 -57.074 1.00 87.19 ? 195 ARG A CZ 1 ATOM 1543 N NH1 . ARG A 1 199 ? 8.458 2.227 -56.822 1.00 106.39 ? 195 ARG A NH1 1 ATOM 1544 N NH2 . ARG A 1 199 ? 10.668 1.618 -56.823 1.00 65.91 ? 195 ARG A NH2 1 ATOM 1545 N N . LEU A 1 200 ? 7.387 -5.300 -58.753 1.00 39.81 ? 196 LEU A N 1 ATOM 1546 C CA . LEU A 1 200 ? 7.694 -6.459 -57.918 1.00 35.85 ? 196 LEU A CA 1 ATOM 1547 C C . LEU A 1 200 ? 8.068 -6.030 -56.505 1.00 45.61 ? 196 LEU A C 1 ATOM 1548 O O . LEU A 1 200 ? 8.527 -4.906 -56.291 1.00 67.96 ? 196 LEU A O 1 ATOM 1549 C CB . LEU A 1 200 ? 8.837 -7.277 -58.522 1.00 42.16 ? 196 LEU A CB 1 ATOM 1550 C CG . LEU A 1 200 ? 8.580 -7.958 -59.865 1.00 42.87 ? 196 LEU A CG 1 ATOM 1551 C CD1 . LEU A 1 200 ? 9.903 -8.325 -60.513 1.00 49.64 ? 196 LEU A CD1 1 ATOM 1552 C CD2 . LEU A 1 200 ? 7.704 -9.190 -59.681 1.00 29.86 ? 196 LEU A CD2 1 ATOM 1553 N N . SER A 1 201 ? 7.875 -6.929 -55.545 1.00 31.82 ? 197 SER A N 1 ATOM 1554 C CA . SER A 1 201 ? 8.262 -6.660 -54.165 1.00 44.38 ? 197 SER A CA 1 ATOM 1555 C C . SER A 1 201 ? 9.777 -6.519 -54.064 1.00 61.48 ? 197 SER A C 1 ATOM 1556 O O . SER A 1 201 ? 10.523 -7.274 -54.689 1.00 66.62 ? 197 SER A O 1 ATOM 1557 C CB . SER A 1 201 ? 7.767 -7.770 -53.234 1.00 43.80 ? 197 SER A CB 1 ATOM 1558 O OG . SER A 1 201 ? 8.333 -9.021 -53.576 1.00 73.62 ? 197 SER A OG 1 ATOM 1559 N N . ALA A 1 202 ? 10.225 -5.543 -53.281 1.00 60.27 ? 198 ALA A N 1 ATOM 1560 C CA . ALA A 1 202 ? 11.651 -5.298 -53.101 1.00 64.50 ? 198 ALA A CA 1 ATOM 1561 C C . ALA A 1 202 ? 12.290 -6.433 -52.309 1.00 64.53 ? 198 ALA A C 1 ATOM 1562 O O . ALA A 1 202 ? 13.269 -7.038 -52.750 1.00 74.61 ? 198 ALA A O 1 ATOM 1563 C CB . ALA A 1 202 ? 11.874 -3.965 -52.399 1.00 72.38 ? 198 ALA A CB 1 ATOM 1564 N N . THR A 1 203 ? 11.720 -6.719 -51.142 1.00 56.10 ? 199 THR A N 1 ATOM 1565 C CA . THR A 1 203 ? 12.202 -7.795 -50.283 1.00 70.77 ? 199 THR A CA 1 ATOM 1566 C C . THR A 1 203 ? 11.385 -9.060 -50.510 1.00 73.22 ? 199 THR A C 1 ATOM 1567 O O . THR A 1 203 ? 10.163 -9.001 -50.658 1.00 65.73 ? 199 THR A O 1 ATOM 1568 C CB . THR A 1 203 ? 12.135 -7.401 -48.796 1.00 74.81 ? 199 THR A CB 1 ATOM 1569 O OG1 . THR A 1 203 ? 10.797 -7.011 -48.461 1.00 93.80 ? 199 THR A OG1 1 ATOM 1570 C CG2 . THR A 1 203 ? 13.088 -6.249 -48.507 1.00 59.20 ? 199 THR A CG2 1 ATOM 1571 N N . LYS A 1 204 ? 12.067 -10.201 -50.538 1.00 74.56 ? 200 LYS A N 1 ATOM 1572 C CA . LYS A 1 204 ? 11.423 -11.483 -50.788 1.00 51.19 ? 200 LYS A CA 1 ATOM 1573 C C . LYS A 1 204 ? 11.145 -12.210 -49.481 1.00 49.76 ? 200 LYS A C 1 ATOM 1574 O O . LYS A 1 204 ? 12.022 -12.321 -48.624 1.00 51.14 ? 200 LYS A O 1 ATOM 1575 C CB . LYS A 1 204 ? 12.296 -12.352 -51.689 1.00 47.16 ? 200 LYS A CB 1 ATOM 1576 C CG . LYS A 1 204 ? 12.910 -11.611 -52.859 1.00 57.85 ? 200 LYS A CG 1 ATOM 1577 C CD . LYS A 1 204 ? 13.720 -12.553 -53.725 1.00 59.53 ? 200 LYS A CD 1 ATOM 1578 C CE . LYS A 1 204 ? 14.609 -11.793 -54.688 1.00 68.40 ? 200 LYS A CE 1 ATOM 1579 N NZ . LYS A 1 204 ? 15.334 -12.714 -55.603 1.00 63.78 ? 200 LYS A NZ 1 ATOM 1580 N N . GLY A 1 205 ? 9.919 -12.698 -49.331 1.00 56.61 ? 201 GLY A N 1 ATOM 1581 C CA . GLY A 1 205 ? 9.553 -13.475 -48.165 1.00 63.55 ? 201 GLY A CA 1 ATOM 1582 C C . GLY A 1 205 ? 9.888 -14.936 -48.374 1.00 66.66 ? 201 GLY A C 1 ATOM 1583 O O . GLY A 1 205 ? 9.825 -15.441 -49.496 1.00 67.04 ? 201 GLY A O 1 ATOM 1584 N N . ARG A 1 206 ? 10.241 -15.614 -47.288 1.00 63.55 ? 202 ARG A N 1 ATOM 1585 C CA . ARG A 1 206 ? 10.573 -17.030 -47.336 1.00 64.12 ? 202 ARG A CA 1 ATOM 1586 C C . ARG A 1 206 ? 9.900 -17.737 -46.172 1.00 68.49 ? 202 ARG A C 1 ATOM 1587 O O . ARG A 1 206 ? 9.743 -17.161 -45.095 1.00 74.69 ? 202 ARG A O 1 ATOM 1588 C CB . ARG A 1 206 ? 12.089 -17.237 -47.285 1.00 78.39 ? 202 ARG A CB 1 ATOM 1589 C CG . ARG A 1 206 ? 12.543 -18.614 -47.733 1.00 76.25 ? 202 ARG A CG 1 ATOM 1590 C CD . ARG A 1 206 ? 14.058 -18.702 -47.803 1.00 78.04 ? 202 ARG A CD 1 ATOM 1591 N NE . ARG A 1 206 ? 14.560 -19.969 -47.274 1.00 72.09 ? 202 ARG A NE 1 ATOM 1592 C CZ . ARG A 1 206 ? 14.936 -20.166 -46.013 1.00 75.16 ? 202 ARG A CZ 1 ATOM 1593 N NH1 . ARG A 1 206 ? 14.879 -19.183 -45.124 1.00 90.23 ? 202 ARG A NH1 1 ATOM 1594 N NH2 . ARG A 1 206 ? 15.376 -21.358 -45.637 1.00 74.55 ? 202 ARG A NH2 1 ATOM 1595 N N . LEU A 1 207 ? 9.502 -18.985 -46.388 1.00 70.08 ? 203 LEU A N 1 ATOM 1596 C CA . LEU A 1 207 ? 8.867 -19.758 -45.335 1.00 70.92 ? 203 LEU A CA 1 ATOM 1597 C C . LEU A 1 207 ? 9.929 -20.272 -44.377 1.00 75.00 ? 203 LEU A C 1 ATOM 1598 O O . LEU A 1 207 ? 10.839 -20.999 -44.778 1.00 79.56 ? 203 LEU A O 1 ATOM 1599 C CB . LEU A 1 207 ? 8.065 -20.921 -45.922 1.00 68.61 ? 203 LEU A CB 1 ATOM 1600 C CG . LEU A 1 207 ? 6.834 -20.527 -46.738 1.00 58.10 ? 203 LEU A CG 1 ATOM 1601 C CD1 . LEU A 1 207 ? 6.252 -21.741 -47.442 1.00 55.76 ? 203 LEU A CD1 1 ATOM 1602 C CD2 . LEU A 1 207 ? 5.785 -19.872 -45.846 1.00 79.31 ? 203 LEU A CD2 1 ATOM 1603 N N . VAL A 1 208 ? 9.814 -19.876 -43.113 1.00 69.66 ? 204 VAL A N 1 ATOM 1604 C CA . VAL A 1 208 ? 10.704 -20.374 -42.075 1.00 71.03 ? 204 VAL A CA 1 ATOM 1605 C C . VAL A 1 208 ? 9.959 -21.441 -41.292 1.00 77.34 ? 204 VAL A C 1 ATOM 1606 O O . VAL A 1 208 ? 9.075 -21.133 -40.491 1.00 77.33 ? 204 VAL A O 1 ATOM 1607 C CB . VAL A 1 208 ? 11.172 -19.247 -41.132 1.00 72.50 ? 204 VAL A CB 1 ATOM 1608 C CG1 . VAL A 1 208 ? 12.018 -19.813 -39.992 1.00 81.93 ? 204 VAL A CG1 1 ATOM 1609 C CG2 . VAL A 1 208 ? 11.949 -18.196 -41.916 1.00 72.02 ? 204 VAL A CG2 1 ATOM 1610 N N . ILE A 1 209 ? 10.345 -22.694 -41.508 1.00 75.11 ? 205 ILE A N 1 ATOM 1611 C CA . ILE A 1 209 ? 9.639 -23.821 -40.917 1.00 73.13 ? 205 ILE A CA 1 ATOM 1612 C C . ILE A 1 209 ? 10.401 -24.337 -39.710 1.00 72.20 ? 205 ILE A C 1 ATOM 1613 O O . ILE A 1 209 ? 11.492 -24.894 -39.836 1.00 82.90 ? 205 ILE A O 1 ATOM 1614 C CB . ILE A 1 209 ? 9.435 -24.974 -41.931 1.00 66.77 ? 205 ILE A CB 1 ATOM 1615 C CG1 . ILE A 1 209 ? 8.616 -24.496 -43.131 1.00 68.45 ? 205 ILE A CG1 1 ATOM 1616 C CG2 . ILE A 1 209 ? 8.733 -26.158 -41.274 1.00 60.13 ? 205 ILE A CG2 1 ATOM 1617 C CD1 . ILE A 1 209 ? 9.448 -23.927 -44.252 1.00 74.87 ? 205 ILE A CD1 1 ATOM 1618 N N . THR A 1 210 ? 9.816 -24.134 -38.537 1.00 69.44 ? 206 THR A N 1 ATOM 1619 C CA . THR A 1 210 ? 10.327 -24.734 -37.320 1.00 66.23 ? 206 THR A CA 1 ATOM 1620 C C . THR A 1 210 ? 9.855 -26.186 -37.337 1.00 80.91 ? 206 THR A C 1 ATOM 1621 O O . THR A 1 210 ? 9.048 -26.561 -38.189 1.00 56.34 ? 206 THR A O 1 ATOM 1622 C CB . THR A 1 210 ? 9.817 -23.958 -36.073 1.00 75.60 ? 206 THR A CB 1 ATOM 1623 O OG1 . THR A 1 210 ? 10.319 -22.616 -36.113 1.00 92.40 ? 206 THR A OG1 1 ATOM 1624 C CG2 . THR A 1 210 ? 10.247 -24.608 -34.766 1.00 66.67 ? 206 THR A CG2 1 ATOM 1625 N N . GLU A 1 211 ? 10.323 -26.991 -36.391 1.00 94.07 ? 207 GLU A N 1 ATOM 1626 C CA . GLU A 1 211 ? 9.955 -28.399 -36.327 1.00 77.96 ? 207 GLU A CA 1 ATOM 1627 C C . GLU A 1 211 ? 9.142 -28.626 -35.059 1.00 85.12 ? 207 GLU A C 1 ATOM 1628 O O . GLU A 1 211 ? 9.255 -27.855 -34.105 1.00 93.28 ? 207 GLU A O 1 ATOM 1629 C CB . GLU A 1 211 ? 11.203 -29.286 -36.347 1.00 67.95 ? 207 GLU A CB 1 ATOM 1630 C CG . GLU A 1 211 ? 12.185 -28.963 -37.476 1.00 70.09 ? 207 GLU A CG 1 ATOM 1631 C CD . GLU A 1 211 ? 11.713 -29.448 -38.834 1.00 83.42 ? 207 GLU A CD 1 ATOM 1632 O OE1 . GLU A 1 211 ? 11.067 -30.514 -38.896 1.00 91.10 ? 207 GLU A OE1 1 ATOM 1633 O OE2 . GLU A 1 211 ? 11.992 -28.763 -39.841 1.00 87.38 ? 207 GLU A OE2 1 ATOM 1634 N N . PRO A 1 212 ? 8.313 -29.679 -35.039 1.00 78.93 ? 208 PRO A N 1 ATOM 1635 C CA . PRO A 1 212 ? 7.484 -29.910 -33.854 1.00 85.94 ? 208 PRO A CA 1 ATOM 1636 C C . PRO A 1 212 ? 8.341 -30.237 -32.634 1.00 96.05 ? 208 PRO A C 1 ATOM 1637 O O . PRO A 1 212 ? 8.446 -31.390 -32.211 1.00 103.78 ? 208 PRO A O 1 ATOM 1638 C CB . PRO A 1 212 ? 6.603 -31.093 -34.268 1.00 88.32 ? 208 PRO A CB 1 ATOM 1639 C CG . PRO A 1 212 ? 7.353 -31.771 -35.365 1.00 92.52 ? 208 PRO A CG 1 ATOM 1640 C CD . PRO A 1 212 ? 8.050 -30.668 -36.098 1.00 78.84 ? 208 PRO A CD 1 ATOM 1641 N N . VAL A 1 213 ? 8.976 -29.198 -32.100 1.00 92.68 ? 209 VAL A N 1 ATOM 1642 C CA . VAL A 1 213 ? 9.828 -29.321 -30.926 1.00 94.98 ? 209 VAL A CA 1 ATOM 1643 C C . VAL A 1 213 ? 9.008 -29.897 -29.771 1.00 91.98 ? 209 VAL A C 1 ATOM 1644 O O . VAL A 1 213 ? 9.336 -30.957 -29.235 1.00 101.73 ? 209 VAL A O 1 ATOM 1645 C CB . VAL A 1 213 ? 10.471 -27.924 -30.558 1.00 105.44 ? 209 VAL A CB 1 ATOM 1646 C CG1 . VAL A 1 213 ? 10.027 -27.385 -29.181 1.00 99.76 ? 209 VAL A CG1 1 ATOM 1647 C CG2 . VAL A 1 213 ? 12.000 -27.967 -30.649 1.00 113.25 ? 209 VAL A CG2 1 ATOM 1648 N N . GLY A 1 214 ? 7.943 -29.193 -29.402 1.00 96.60 ? 210 GLY A N 1 ATOM 1649 C CA . GLY A 1 214 ? 7.058 -29.610 -28.332 1.00 109.32 ? 210 GLY A CA 1 ATOM 1650 C C . GLY A 1 214 ? 5.671 -29.977 -28.817 1.00 100.26 ? 210 GLY A C 1 ATOM 1651 O O . GLY A 1 214 ? 5.465 -30.342 -29.975 1.00 96.28 ? 210 GLY A O 1 ATOM 1652 N N . SER A 1 215 ? 4.720 -29.877 -27.895 1.00 94.19 ? 211 SER A N 1 ATOM 1653 C CA . SER A 1 215 ? 3.301 -29.839 -28.212 1.00 82.15 ? 211 SER A CA 1 ATOM 1654 C C . SER A 1 215 ? 2.717 -28.734 -27.343 1.00 83.76 ? 211 SER A C 1 ATOM 1655 O O . SER A 1 215 ? 2.831 -28.784 -26.117 1.00 77.72 ? 211 SER A O 1 ATOM 1656 C CB . SER A 1 215 ? 2.624 -31.180 -27.941 1.00 81.15 ? 211 SER A CB 1 ATOM 1657 O OG . SER A 1 215 ? 2.721 -31.524 -26.572 1.00 92.24 ? 211 SER A OG 1 ATOM 1658 N N . LYS A 1 216 ? 2.097 -27.740 -27.972 1.00 81.03 ? 212 LYS A N 1 ATOM 1659 C CA . LYS A 1 216 ? 1.777 -26.493 -27.285 1.00 79.05 ? 212 LYS A CA 1 ATOM 1660 C C . LYS A 1 216 ? 0.383 -25.965 -27.600 1.00 78.61 ? 212 LYS A C 1 ATOM 1661 O O . LYS A 1 216 ? -0.372 -26.565 -28.366 1.00 79.88 ? 212 LYS A O 1 ATOM 1662 C CB . LYS A 1 216 ? 2.812 -25.433 -27.654 1.00 82.56 ? 212 LYS A CB 1 ATOM 1663 C CG . LYS A 1 216 ? 2.825 -25.118 -29.132 1.00 75.37 ? 212 LYS A CG 1 ATOM 1664 C CD . LYS A 1 216 ? 3.962 -24.200 -29.511 1.00 83.40 ? 212 LYS A CD 1 ATOM 1665 C CE . LYS A 1 216 ? 3.923 -23.924 -30.998 1.00 84.73 ? 212 LYS A CE 1 ATOM 1666 N NZ . LYS A 1 216 ? 2.682 -23.187 -31.375 1.00 82.75 ? 212 LYS A NZ 1 ATOM 1667 N N . ALA A 1 217 ? 0.062 -24.824 -27.000 1.00 89.21 ? 213 ALA A N 1 ATOM 1668 C CA . ALA A 1 217 ? -1.235 -24.186 -27.173 1.00 85.05 ? 213 ALA A CA 1 ATOM 1669 C C . ALA A 1 217 ? -1.393 -23.613 -28.577 1.00 85.72 ? 213 ALA A C 1 ATOM 1670 O O . ALA A 1 217 ? -0.401 -23.371 -29.265 1.00 94.17 ? 213 ALA A O 1 ATOM 1671 C CB . ALA A 1 217 ? -1.415 -23.084 -26.142 1.00 83.05 ? 213 ALA A CB 1 ATOM 1672 N N . PRO A 1 218 ? -2.646 -23.403 -29.014 1.00 70.23 ? 214 PRO A N 1 ATOM 1673 C CA . PRO A 1 218 ? -2.868 -22.625 -30.237 1.00 68.34 ? 214 PRO A CA 1 ATOM 1674 C C . PRO A 1 218 ? -2.475 -21.169 -30.035 1.00 83.48 ? 214 PRO A C 1 ATOM 1675 O O . PRO A 1 218 ? -2.860 -20.568 -29.031 1.00 90.07 ? 214 PRO A O 1 ATOM 1676 C CB . PRO A 1 218 ? -4.373 -22.773 -30.487 1.00 71.64 ? 214 PRO A CB 1 ATOM 1677 C CG . PRO A 1 218 ? -4.787 -23.979 -29.688 1.00 69.39 ? 214 PRO A CG 1 ATOM 1678 C CD . PRO A 1 218 ? -3.900 -23.964 -28.488 1.00 67.59 ? 214 PRO A CD 1 ATOM 1679 N N . THR A 1 219 ? -1.714 -20.620 -30.977 1.00 79.37 ? 215 THR A N 1 ATOM 1680 C CA . THR A 1 219 ? -1.204 -19.261 -30.851 1.00 81.22 ? 215 THR A CA 1 ATOM 1681 C C . THR A 1 219 ? -1.515 -18.439 -32.094 1.00 79.28 ? 215 THR A C 1 ATOM 1682 O O . THR A 1 219 ? -1.000 -18.707 -33.181 1.00 73.40 ? 215 THR A O 1 ATOM 1683 C CB . THR A 1 219 ? 0.316 -19.260 -30.600 1.00 73.17 ? 215 THR A CB 1 ATOM 1684 O OG1 . THR A 1 219 ? 0.993 -19.836 -31.724 1.00 71.91 ? 215 THR A OG1 1 ATOM 1685 C CG2 . THR A 1 219 ? 0.642 -20.059 -29.342 1.00 70.97 ? 215 THR A CG2 1 ATOM 1686 N N . PHE A 1 220 ? -2.366 -17.434 -31.919 1.00 70.92 ? 216 PHE A N 1 ATOM 1687 C CA . PHE A 1 220 ? -2.688 -16.502 -32.988 1.00 64.84 ? 216 PHE A CA 1 ATOM 1688 C C . PHE A 1 220 ? -1.542 -15.516 -33.176 1.00 69.18 ? 216 PHE A C 1 ATOM 1689 O O . PHE A 1 220 ? -0.743 -15.297 -32.264 1.00 78.19 ? 216 PHE A O 1 ATOM 1690 C CB . PHE A 1 220 ? -3.993 -15.767 -32.685 1.00 80.29 ? 216 PHE A CB 1 ATOM 1691 C CG . PHE A 1 220 ? -5.181 -16.679 -32.557 1.00 80.97 ? 216 PHE A CG 1 ATOM 1692 C CD1 . PHE A 1 220 ? -5.490 -17.270 -31.345 1.00 85.78 ? 216 PHE A CD1 1 ATOM 1693 C CD2 . PHE A 1 220 ? -5.984 -16.953 -33.650 1.00 76.85 ? 216 PHE A CD2 1 ATOM 1694 C CE1 . PHE A 1 220 ? -6.580 -18.113 -31.226 1.00 84.93 ? 216 PHE A CE1 1 ATOM 1695 C CE2 . PHE A 1 220 ? -7.075 -17.792 -33.534 1.00 70.81 ? 216 PHE A CE2 1 ATOM 1696 C CZ . PHE A 1 220 ? -7.370 -18.375 -32.322 1.00 73.53 ? 216 PHE A CZ 1 ATOM 1697 N N . ALA A 1 221 ? -1.463 -14.931 -34.366 1.00 69.72 ? 217 ALA A N 1 ATOM 1698 C CA . ALA A 1 221 ? -0.378 -14.018 -34.705 1.00 72.79 ? 217 ALA A CA 1 ATOM 1699 C C . ALA A 1 221 ? -0.428 -12.743 -33.864 1.00 78.06 ? 217 ALA A C 1 ATOM 1700 O O . ALA A 1 221 ? 0.567 -12.025 -33.761 1.00 85.00 ? 217 ALA A O 1 ATOM 1701 C CB . ALA A 1 221 ? -0.427 -13.676 -36.189 1.00 75.89 ? 217 ALA A CB 1 ATOM 1702 N N . THR A 1 222 ? -1.585 -12.469 -33.265 1.00 81.53 ? 218 THR A N 1 ATOM 1703 C CA . THR A 1 222 ? -1.756 -11.287 -32.426 1.00 77.77 ? 218 THR A CA 1 ATOM 1704 C C . THR A 1 222 ? -2.559 -11.612 -31.172 1.00 76.84 ? 218 THR A C 1 ATOM 1705 O O . THR A 1 222 ? -3.208 -12.655 -31.087 1.00 79.27 ? 218 THR A O 1 ATOM 1706 C CB . THR A 1 222 ? -2.459 -10.146 -33.189 1.00 85.01 ? 218 THR A CB 1 ATOM 1707 O OG1 . THR A 1 222 ? -3.762 -10.574 -33.605 1.00 83.85 ? 218 THR A OG1 1 ATOM 1708 C CG2 . THR A 1 222 ? -1.643 -9.729 -34.408 1.00 89.19 ? 218 THR A CG2 1 ATOM 1709 N N . ALA A 1 223 ? -2.509 -10.704 -30.204 1.00 78.83 ? 219 ALA A N 1 ATOM 1710 C CA . ALA A 1 223 ? -3.213 -10.879 -28.941 1.00 93.99 ? 219 ALA A CA 1 ATOM 1711 C C . ALA A 1 223 ? -4.672 -10.448 -29.060 1.00 95.59 ? 219 ALA A C 1 ATOM 1712 O O . ALA A 1 223 ? -5.431 -10.533 -28.094 1.00 90.65 ? 219 ALA A O 1 ATOM 1713 C CB . ALA A 1 223 ? -2.518 -10.093 -27.841 1.00 104.05 ? 219 ALA A CB 1 ATOM 1714 N N . SER A 1 224 ? -5.064 -9.993 -30.247 1.00 94.60 ? 220 SER A N 1 ATOM 1715 C CA . SER A 1 224 ? -6.421 -9.502 -30.452 1.00 77.35 ? 220 SER A CA 1 ATOM 1716 C C . SER A 1 224 ? -7.407 -10.662 -30.508 1.00 79.59 ? 220 SER A C 1 ATOM 1717 O O . SER A 1 224 ? -7.297 -11.550 -31.353 1.00 80.78 ? 220 SER A O 1 ATOM 1718 C CB . SER A 1 224 ? -6.505 -8.675 -31.738 1.00 71.41 ? 220 SER A CB 1 ATOM 1719 O OG . SER A 1 224 ? -7.771 -8.050 -31.860 1.00 71.51 ? 220 SER A OG 1 ATOM 1720 N N . LYS A 1 225 ? -8.370 -10.639 -29.591 1.00 85.10 ? 221 LYS A N 1 ATOM 1721 C CA . LYS A 1 225 ? -9.434 -11.635 -29.542 1.00 77.14 ? 221 LYS A CA 1 ATOM 1722 C C . LYS A 1 225 ? -10.672 -11.176 -30.309 1.00 59.80 ? 221 LYS A C 1 ATOM 1723 O O . LYS A 1 225 ? -11.685 -11.876 -30.339 1.00 57.92 ? 221 LYS A O 1 ATOM 1724 C CB . LYS A 1 225 ? -9.800 -11.946 -28.090 1.00 73.58 ? 221 LYS A CB 1 ATOM 1725 C CG . LYS A 1 225 ? -9.304 -13.300 -27.617 1.00 74.99 ? 221 LYS A CG 1 ATOM 1726 C CD . LYS A 1 225 ? -7.789 -13.415 -27.712 1.00 91.11 ? 221 LYS A CD 1 ATOM 1727 C CE . LYS A 1 225 ? -7.304 -14.752 -27.179 1.00 85.62 ? 221 LYS A CE 1 ATOM 1728 N NZ . LYS A 1 225 ? -7.919 -15.896 -27.912 1.00 72.35 ? 221 LYS A NZ 1 ATOM 1729 N N . ILE A 1 226 ? -10.588 -10.000 -30.926 1.00 54.41 ? 222 ILE A N 1 ATOM 1730 C CA . ILE A 1 226 ? -11.673 -9.501 -31.762 1.00 57.74 ? 222 ILE A CA 1 ATOM 1731 C C . ILE A 1 226 ? -11.136 -8.674 -32.922 1.00 56.58 ? 222 ILE A C 1 ATOM 1732 O O . ILE A 1 226 ? -10.089 -8.035 -32.817 1.00 72.65 ? 222 ILE A O 1 ATOM 1733 C CB . ILE A 1 226 ? -12.674 -8.645 -30.958 1.00 65.37 ? 222 ILE A CB 1 ATOM 1734 C CG1 . ILE A 1 226 ? -13.928 -8.373 -31.795 1.00 57.59 ? 222 ILE A CG1 1 ATOM 1735 C CG2 . ILE A 1 226 ? -12.029 -7.334 -30.509 1.00 72.96 ? 222 ILE A CG2 1 ATOM 1736 C CD1 . ILE A 1 226 ? -15.064 -7.751 -31.013 1.00 64.49 ? 222 ILE A CD1 1 ATOM 1737 N N . SER A 1 227 ? -11.870 -8.696 -34.028 1.00 52.64 ? 223 SER A N 1 ATOM 1738 C CA . SER A 1 227 ? -11.514 -7.928 -35.211 1.00 56.43 ? 223 SER A CA 1 ATOM 1739 C C . SER A 1 227 ? -12.782 -7.465 -35.908 1.00 64.08 ? 223 SER A C 1 ATOM 1740 O O . SER A 1 227 ? -13.890 -7.750 -35.452 1.00 67.73 ? 223 SER A O 1 ATOM 1741 C CB . SER A 1 227 ? -10.659 -8.764 -36.165 1.00 60.33 ? 223 SER A CB 1 ATOM 1742 O OG . SER A 1 227 ? -11.357 -9.919 -36.599 1.00 46.76 ? 223 SER A OG 1 ATOM 1743 N N . SER A 1 228 ? -12.617 -6.743 -37.009 1.00 48.31 ? 224 SER A N 1 ATOM 1744 C CA . SER A 1 228 ? -13.744 -6.394 -37.856 1.00 38.08 ? 224 SER A CA 1 ATOM 1745 C C . SER A 1 228 ? -13.262 -6.207 -39.283 1.00 50.39 ? 224 SER A C 1 ATOM 1746 O O . SER A 1 228 ? -12.100 -5.877 -39.517 1.00 65.54 ? 224 SER A O 1 ATOM 1747 C CB . SER A 1 228 ? -14.438 -5.123 -37.363 1.00 38.31 ? 224 SER A CB 1 ATOM 1748 O OG . SER A 1 228 ? -13.708 -3.967 -37.725 1.00 62.37 ? 224 SER A OG 1 ATOM 1749 N N . LEU A 1 229 ? -14.160 -6.427 -40.235 1.00 46.14 ? 225 LEU A N 1 ATOM 1750 C CA . LEU A 1 229 ? -13.856 -6.190 -41.636 1.00 56.36 ? 225 LEU A CA 1 ATOM 1751 C C . LEU A 1 229 ? -15.136 -5.868 -42.382 1.00 52.45 ? 225 LEU A C 1 ATOM 1752 O O . LEU A 1 229 ? -16.233 -6.181 -41.918 1.00 51.16 ? 225 LEU A O 1 ATOM 1753 C CB . LEU A 1 229 ? -13.162 -7.399 -42.268 1.00 54.65 ? 225 LEU A CB 1 ATOM 1754 C CG . LEU A 1 229 ? -13.996 -8.673 -42.438 1.00 53.94 ? 225 LEU A CG 1 ATOM 1755 C CD1 . LEU A 1 229 ? -13.490 -9.491 -43.619 1.00 45.58 ? 225 LEU A CD1 1 ATOM 1756 C CD2 . LEU A 1 229 ? -13.976 -9.499 -41.161 1.00 62.80 ? 225 LEU A CD2 1 ATOM 1757 N N . LEU A 1 230 ? -14.980 -5.253 -43.546 1.00 55.01 ? 226 LEU A N 1 ATOM 1758 C CA . LEU A 1 230 ? -16.107 -4.844 -44.364 1.00 47.03 ? 226 LEU A CA 1 ATOM 1759 C C . LEU A 1 230 ? -15.904 -5.353 -45.780 1.00 57.24 ? 226 LEU A C 1 ATOM 1760 O O . LEU A 1 230 ? -14.771 -5.515 -46.233 1.00 60.60 ? 226 LEU A O 1 ATOM 1761 C CB . LEU A 1 230 ? -16.249 -3.322 -44.343 1.00 42.26 ? 226 LEU A CB 1 ATOM 1762 C CG . LEU A 1 230 ? -17.478 -2.724 -45.024 1.00 47.58 ? 226 LEU A CG 1 ATOM 1763 C CD1 . LEU A 1 230 ? -17.928 -1.494 -44.255 1.00 46.35 ? 226 LEU A CD1 1 ATOM 1764 C CD2 . LEU A 1 230 ? -17.192 -2.372 -46.480 1.00 50.26 ? 226 LEU A CD2 1 ATOM 1765 N N . GLY A 1 231 ? -17.006 -5.610 -46.474 1.00 48.84 ? 227 GLY A N 1 ATOM 1766 C CA . GLY A 1 231 ? -16.947 -6.077 -47.844 1.00 51.67 ? 227 GLY A CA 1 ATOM 1767 C C . GLY A 1 231 ? -18.187 -5.660 -48.601 1.00 36.72 ? 227 GLY A C 1 ATOM 1768 O O . GLY A 1 231 ? -19.232 -5.411 -48.000 1.00 34.63 ? 227 GLY A O 1 ATOM 1769 N N . SER A 1 232 ? -18.074 -5.582 -49.923 1.00 36.21 ? 228 SER A N 1 ATOM 1770 C CA . SER A 1 232 ? -19.204 -5.194 -50.753 1.00 47.24 ? 228 SER A CA 1 ATOM 1771 C C . SER A 1 232 ? -20.145 -6.382 -50.907 1.00 49.09 ? 228 SER A C 1 ATOM 1772 O O . SER A 1 232 ? -19.875 -7.467 -50.392 1.00 62.70 ? 228 SER A O 1 ATOM 1773 C CB . SER A 1 232 ? -18.734 -4.697 -52.122 1.00 42.66 ? 228 SER A CB 1 ATOM 1774 O OG . SER A 1 232 ? -18.491 -5.776 -53.002 1.00 51.30 ? 228 SER A OG 1 ATOM 1775 N N . SER A 1 233 ? -21.247 -6.175 -51.617 1.00 44.05 ? 229 SER A N 1 ATOM 1776 C CA . SER A 1 233 ? -22.270 -7.202 -51.750 1.00 41.18 ? 229 SER A CA 1 ATOM 1777 C C . SER A 1 233 ? -21.866 -8.299 -52.732 1.00 49.99 ? 229 SER A C 1 ATOM 1778 O O . SER A 1 233 ? -21.940 -9.484 -52.411 1.00 59.21 ? 229 SER A O 1 ATOM 1779 C CB . SER A 1 233 ? -23.591 -6.566 -52.188 1.00 61.97 ? 229 SER A CB 1 ATOM 1780 O OG . SER A 1 233 ? -24.138 -5.774 -51.148 1.00 57.75 ? 229 SER A OG 1 ATOM 1781 N N . SER A 1 234 ? -21.420 -7.903 -53.919 1.00 39.54 ? 230 SER A N 1 ATOM 1782 C CA . SER A 1 234 ? -21.108 -8.859 -54.978 1.00 51.13 ? 230 SER A CA 1 ATOM 1783 C C . SER A 1 234 ? -19.692 -9.416 -54.850 1.00 61.44 ? 230 SER A C 1 ATOM 1784 O O . SER A 1 234 ? -19.331 -10.377 -55.533 1.00 48.84 ? 230 SER A O 1 ATOM 1785 C CB . SER A 1 234 ? -21.287 -8.203 -56.347 1.00 55.90 ? 230 SER A CB 1 ATOM 1786 O OG . SER A 1 234 ? -22.630 -7.806 -56.544 1.00 62.66 ? 230 SER A OG 1 ATOM 1787 N N . SER A 1 235 ? -18.895 -8.814 -53.972 1.00 60.40 ? 231 SER A N 1 ATOM 1788 C CA . SER A 1 235 ? -17.513 -9.240 -53.781 1.00 61.43 ? 231 SER A CA 1 ATOM 1789 C C . SER A 1 235 ? -17.442 -10.561 -53.035 1.00 57.04 ? 231 SER A C 1 ATOM 1790 O O . SER A 1 235 ? -18.392 -10.960 -52.361 1.00 47.72 ? 231 SER A O 1 ATOM 1791 C CB . SER A 1 235 ? -16.713 -8.180 -53.019 1.00 66.73 ? 231 SER A CB 1 ATOM 1792 O OG . SER A 1 235 ? -17.288 -7.912 -51.751 1.00 56.47 ? 231 SER A OG 1 ATOM 1793 N N . ASP A 1 236 ? -16.300 -11.231 -53.163 1.00 61.11 ? 232 ASP A N 1 ATOM 1794 C CA . ASP A 1 236 ? -16.047 -12.467 -52.442 1.00 52.65 ? 232 ASP A CA 1 ATOM 1795 C C . ASP A 1 236 ? -15.189 -12.151 -51.225 1.00 40.76 ? 232 ASP A C 1 ATOM 1796 O O . ASP A 1 236 ? -14.010 -11.824 -51.351 1.00 63.99 ? 232 ASP A O 1 ATOM 1797 C CB . ASP A 1 236 ? -15.358 -13.489 -53.349 1.00 56.63 ? 232 ASP A CB 1 ATOM 1798 C CG . ASP A 1 236 ? -16.080 -13.674 -54.674 1.00 69.23 ? 232 ASP A CG 1 ATOM 1799 O OD1 . ASP A 1 236 ? -16.924 -12.820 -55.018 1.00 63.39 ? 232 ASP A OD1 1 ATOM 1800 O OD2 . ASP A 1 236 ? -15.796 -14.666 -55.379 1.00 70.85 ? 232 ASP A OD2 1 ATOM 1801 N N . ILE A 1 237 ? -15.792 -12.254 -50.045 1.00 35.84 ? 233 ILE A N 1 ATOM 1802 C CA . ILE A 1 237 ? -15.151 -11.812 -48.811 1.00 35.73 ? 233 ILE A CA 1 ATOM 1803 C C . ILE A 1 237 ? -14.447 -12.972 -48.121 1.00 42.19 ? 233 ILE A C 1 ATOM 1804 O O . ILE A 1 237 ? -14.920 -14.108 -48.162 1.00 43.83 ? 233 ILE A O 1 ATOM 1805 C CB . ILE A 1 237 ? -16.171 -11.180 -47.840 1.00 37.79 ? 233 ILE A CB 1 ATOM 1806 C CG1 . ILE A 1 237 ? -16.983 -10.098 -48.559 1.00 51.67 ? 233 ILE A CG1 1 ATOM 1807 C CG2 . ILE A 1 237 ? -15.456 -10.602 -46.613 1.00 42.21 ? 233 ILE A CG2 1 ATOM 1808 C CD1 . ILE A 1 237 ? -18.113 -9.518 -47.734 1.00 51.37 ? 233 ILE A CD1 1 ATOM 1809 N N . VAL A 1 238 ? -13.310 -12.675 -47.498 1.00 51.36 ? 234 VAL A N 1 ATOM 1810 C CA . VAL A 1 238 ? -12.504 -13.694 -46.837 1.00 44.41 ? 234 VAL A CA 1 ATOM 1811 C C . VAL A 1 238 ? -12.231 -13.348 -45.377 1.00 46.97 ? 234 VAL A C 1 ATOM 1812 O O . VAL A 1 238 ? -11.528 -12.383 -45.074 1.00 44.65 ? 234 VAL A O 1 ATOM 1813 C CB . VAL A 1 238 ? -11.157 -13.891 -47.560 1.00 46.60 ? 234 VAL A CB 1 ATOM 1814 C CG1 . VAL A 1 238 ? -10.378 -15.046 -46.936 1.00 39.71 ? 234 VAL A CG1 1 ATOM 1815 C CG2 . VAL A 1 238 ? -11.391 -14.137 -49.045 1.00 44.14 ? 234 VAL A CG2 1 ATOM 1816 N N . LEU A 1 239 ? -12.804 -14.142 -44.479 1.00 54.01 ? 235 LEU A N 1 ATOM 1817 C CA . LEU A 1 239 ? -12.430 -14.119 -43.072 1.00 51.48 ? 235 LEU A CA 1 ATOM 1818 C C . LEU A 1 239 ? -11.171 -14.953 -42.892 1.00 48.95 ? 235 LEU A C 1 ATOM 1819 O O . LEU A 1 239 ? -10.889 -15.837 -43.702 1.00 49.47 ? 235 LEU A O 1 ATOM 1820 C CB . LEU A 1 239 ? -13.559 -14.648 -42.188 1.00 47.56 ? 235 LEU A CB 1 ATOM 1821 C CG . LEU A 1 239 ? -14.811 -13.774 -42.114 1.00 44.43 ? 235 LEU A CG 1 ATOM 1822 C CD1 . LEU A 1 239 ? -15.660 -13.918 -43.372 1.00 43.28 ? 235 LEU A CD1 1 ATOM 1823 C CD2 . LEU A 1 239 ? -15.612 -14.111 -40.863 1.00 40.53 ? 235 LEU A CD2 1 ATOM 1824 N N . LEU A 1 240 ? -10.416 -14.668 -41.836 1.00 58.54 ? 236 LEU A N 1 ATOM 1825 C CA . LEU A 1 240 ? -9.166 -15.373 -41.579 1.00 58.27 ? 236 LEU A CA 1 ATOM 1826 C C . LEU A 1 240 ? -9.112 -15.986 -40.191 1.00 61.93 ? 236 LEU A C 1 ATOM 1827 O O . LEU A 1 240 ? -9.641 -15.432 -39.225 1.00 39.98 ? 236 LEU A O 1 ATOM 1828 C CB . LEU A 1 240 ? -7.975 -14.429 -41.742 1.00 52.99 ? 236 LEU A CB 1 ATOM 1829 C CG . LEU A 1 240 ? -7.799 -13.740 -43.091 1.00 53.91 ? 236 LEU A CG 1 ATOM 1830 C CD1 . LEU A 1 240 ? -6.725 -12.673 -42.963 1.00 67.11 ? 236 LEU A CD1 1 ATOM 1831 C CD2 . LEU A 1 240 ? -7.445 -14.747 -44.180 1.00 42.96 ? 236 LEU A CD2 1 ATOM 1832 N N . CYS A 1 241 ? -8.474 -17.148 -40.114 1.00 74.77 ? 237 CYS A N 1 ATOM 1833 C CA . CYS A 1 241 ? -7.976 -17.673 -38.856 1.00 77.65 ? 237 CYS A CA 1 ATOM 1834 C C . CYS A 1 241 ? -6.506 -18.013 -39.065 1.00 64.33 ? 237 CYS A C 1 ATOM 1835 O O . CYS A 1 241 ? -6.169 -18.949 -39.790 1.00 78.47 ? 237 CYS A O 1 ATOM 1836 C CB . CYS A 1 241 ? -8.773 -18.897 -38.411 1.00 68.79 ? 237 CYS A CB 1 ATOM 1837 S SG . CYS A 1 241 ? -9.082 -18.954 -36.643 1.00 72.85 ? 237 CYS A SG 1 ATOM 1838 N N . GLN A 1 242 ? -5.637 -17.238 -38.427 1.00 63.39 ? 238 GLN A N 1 ATOM 1839 C CA . GLN A 1 242 ? -4.194 -17.366 -38.604 1.00 80.03 ? 238 GLN A CA 1 ATOM 1840 C C . GLN A 1 242 ? -3.574 -18.250 -37.526 1.00 81.66 ? 238 GLN A C 1 ATOM 1841 O O . GLN A 1 242 ? -2.350 -18.343 -37.413 1.00 80.62 ? 238 GLN A O 1 ATOM 1842 C CB . GLN A 1 242 ? -3.545 -15.981 -38.630 1.00 80.62 ? 238 GLN A CB 1 ATOM 1843 C CG . GLN A 1 242 ? -3.624 -15.338 -40.007 1.00 75.50 ? 238 GLN A CG 1 ATOM 1844 C CD . GLN A 1 242 ? -3.132 -13.908 -40.028 1.00 67.59 ? 238 GLN A CD 1 ATOM 1845 O OE1 . GLN A 1 242 ? -3.489 -13.102 -39.170 1.00 69.92 ? 238 GLN A OE1 1 ATOM 1846 N NE2 . GLN A 1 242 ? -2.309 -13.582 -41.018 1.00 69.46 ? 238 GLN A NE2 1 ATOM 1847 N N . ALA A 1 243 ? -4.436 -18.885 -36.735 1.00 74.55 ? 239 ALA A N 1 ATOM 1848 C CA . ALA A 1 243 ? -4.014 -19.713 -35.609 1.00 79.24 ? 239 ALA A CA 1 ATOM 1849 C C . ALA A 1 243 ? -2.929 -20.706 -36.003 1.00 74.04 ? 239 ALA A C 1 ATOM 1850 O O . ALA A 1 243 ? -2.981 -21.316 -37.072 1.00 81.46 ? 239 ALA A O 1 ATOM 1851 C CB . ALA A 1 243 ? -5.208 -20.458 -35.033 1.00 82.51 ? 239 ALA A CB 1 ATOM 1852 N N . GLN A 1 244 ? -1.944 -20.847 -35.124 1.00 71.15 ? 240 GLN A N 1 ATOM 1853 C CA . GLN A 1 244 ? -0.792 -21.704 -35.363 1.00 70.58 ? 240 GLN A CA 1 ATOM 1854 C C . GLN A 1 244 ? -0.558 -22.591 -34.152 1.00 64.23 ? 240 GLN A C 1 ATOM 1855 O O . GLN A 1 244 ? -0.789 -22.166 -33.020 1.00 69.86 ? 240 GLN A O 1 ATOM 1856 C CB . GLN A 1 244 ? 0.450 -20.860 -35.642 1.00 83.95 ? 240 GLN A CB 1 ATOM 1857 C CG . GLN A 1 244 ? 1.209 -21.249 -36.891 1.00 70.29 ? 240 GLN A CG 1 ATOM 1858 C CD . GLN A 1 244 ? 2.702 -21.287 -36.661 1.00 66.93 ? 240 GLN A CD 1 ATOM 1859 O OE1 . GLN A 1 244 ? 3.355 -22.297 -36.920 1.00 76.43 ? 240 GLN A OE1 1 ATOM 1860 N NE2 . GLN A 1 244 ? 3.251 -20.187 -36.162 1.00 67.29 ? 240 GLN A NE2 1 ATOM 1861 N N . ALA A 1 245 ? -0.073 -23.809 -34.381 1.00 65.95 ? 241 ALA A N 1 ATOM 1862 C CA . ALA A 1 245 ? 0.137 -24.755 -33.286 1.00 72.53 ? 241 ALA A CA 1 ATOM 1863 C C . ALA A 1 245 ? 0.773 -26.057 -33.727 1.00 65.93 ? 241 ALA A C 1 ATOM 1864 O O . ALA A 1 245 ? 0.890 -26.347 -34.917 1.00 62.28 ? 241 ALA A O 1 ATOM 1865 C CB . ALA A 1 245 ? -1.186 -25.070 -32.599 1.00 74.04 ? 241 ALA A CB 1 ATOM 1866 N N . PHE A 1 246 ? 1.195 -26.829 -32.733 1.00 69.05 ? 242 PHE A N 1 ATOM 1867 C CA . PHE A 1 246 ? 1.419 -28.255 -32.901 1.00 75.83 ? 242 PHE A CA 1 ATOM 1868 C C . PHE A 1 246 ? 0.866 -28.975 -31.667 1.00 79.63 ? 242 PHE A C 1 ATOM 1869 O O . PHE A 1 246 ? 1.012 -28.476 -30.550 1.00 80.96 ? 242 PHE A O 1 ATOM 1870 C CB . PHE A 1 246 ? 2.902 -28.576 -33.088 1.00 79.67 ? 242 PHE A CB 1 ATOM 1871 C CG . PHE A 1 246 ? 3.172 -30.040 -33.273 1.00 84.73 ? 242 PHE A CG 1 ATOM 1872 C CD1 . PHE A 1 246 ? 3.403 -30.857 -32.182 1.00 80.82 ? 242 PHE A CD1 1 ATOM 1873 C CD2 . PHE A 1 246 ? 3.159 -30.606 -34.536 1.00 85.39 ? 242 PHE A CD2 1 ATOM 1874 C CE1 . PHE A 1 246 ? 3.634 -32.207 -32.348 1.00 73.59 ? 242 PHE A CE1 1 ATOM 1875 C CE2 . PHE A 1 246 ? 3.390 -31.958 -34.706 1.00 68.26 ? 242 PHE A CE2 1 ATOM 1876 C CZ . PHE A 1 246 ? 3.628 -32.757 -33.610 1.00 61.01 ? 242 PHE A CZ 1 ATOM 1877 N N . PRO A 1 247 ? 0.222 -30.142 -31.852 1.00 78.67 ? 243 PRO A N 1 ATOM 1878 C CA . PRO A 1 247 ? -0.128 -30.778 -33.130 1.00 71.63 ? 243 PRO A CA 1 ATOM 1879 C C . PRO A 1 247 ? -1.129 -29.954 -33.935 1.00 72.83 ? 243 PRO A C 1 ATOM 1880 O O . PRO A 1 247 ? -1.942 -29.235 -33.354 1.00 76.91 ? 243 PRO A O 1 ATOM 1881 C CB . PRO A 1 247 ? -0.732 -32.122 -32.706 1.00 62.34 ? 243 PRO A CB 1 ATOM 1882 C CG . PRO A 1 247 ? -1.146 -31.940 -31.284 1.00 66.60 ? 243 PRO A CG 1 ATOM 1883 C CD . PRO A 1 247 ? -0.163 -30.978 -30.701 1.00 69.45 ? 243 PRO A CD 1 ATOM 1884 N N . VAL A 1 248 ? -1.051 -30.060 -35.259 1.00 64.93 ? 244 VAL A N 1 ATOM 1885 C CA . VAL A 1 248 ? -1.856 -29.235 -36.156 1.00 68.36 ? 244 VAL A CA 1 ATOM 1886 C C . VAL A 1 248 ? -3.350 -29.409 -35.859 1.00 67.54 ? 244 VAL A C 1 ATOM 1887 O O . VAL A 1 248 ? -3.876 -30.518 -35.959 1.00 59.50 ? 244 VAL A O 1 ATOM 1888 C CB . VAL A 1 248 ? -1.576 -29.581 -37.633 1.00 61.11 ? 244 VAL A CB 1 ATOM 1889 C CG1 . VAL A 1 248 ? -2.437 -28.726 -38.564 1.00 45.01 ? 244 VAL A CG1 1 ATOM 1890 C CG2 . VAL A 1 248 ? -0.094 -29.390 -37.942 1.00 57.39 ? 244 VAL A CG2 1 ATOM 1891 N N . PRO A 1 249 ? -4.037 -28.313 -35.486 1.00 71.78 ? 245 PRO A N 1 ATOM 1892 C CA . PRO A 1 249 ? -5.439 -28.417 -35.069 1.00 65.66 ? 245 PRO A CA 1 ATOM 1893 C C . PRO A 1 249 ? -6.459 -28.313 -36.197 1.00 61.50 ? 245 PRO A C 1 ATOM 1894 O O . PRO A 1 249 ? -6.105 -28.174 -37.369 1.00 64.86 ? 245 PRO A O 1 ATOM 1895 C CB . PRO A 1 249 ? -5.597 -27.237 -34.115 1.00 68.94 ? 245 PRO A CB 1 ATOM 1896 C CG . PRO A 1 249 ? -4.657 -26.208 -34.642 1.00 70.86 ? 245 PRO A CG 1 ATOM 1897 C CD . PRO A 1 249 ? -3.503 -26.956 -35.263 1.00 64.34 ? 245 PRO A CD 1 ATOM 1898 N N . TYR A 1 250 ? -7.729 -28.376 -35.808 1.00 69.43 ? 246 TYR A N 1 ATOM 1899 C CA . TYR A 1 250 ? -8.855 -28.275 -36.726 1.00 76.28 ? 246 TYR A CA 1 ATOM 1900 C C . TYR A 1 250 ? -9.615 -26.984 -36.451 1.00 69.61 ? 246 TYR A C 1 ATOM 1901 O O . TYR A 1 250 ? -9.629 -26.498 -35.318 1.00 69.59 ? 246 TYR A O 1 ATOM 1902 C CB . TYR A 1 250 ? -9.781 -29.485 -36.574 1.00 66.48 ? 246 TYR A CB 1 ATOM 1903 C CG . TYR A 1 250 ? -10.272 -29.695 -35.156 1.00 61.10 ? 246 TYR A CG 1 ATOM 1904 C CD1 . TYR A 1 250 ? -9.511 -30.400 -34.232 1.00 71.67 ? 246 TYR A CD1 1 ATOM 1905 C CD2 . TYR A 1 250 ? -11.493 -29.186 -34.738 1.00 55.96 ? 246 TYR A CD2 1 ATOM 1906 C CE1 . TYR A 1 250 ? -9.953 -30.592 -32.936 1.00 73.12 ? 246 TYR A CE1 1 ATOM 1907 C CE2 . TYR A 1 250 ? -11.941 -29.376 -33.442 1.00 68.59 ? 246 TYR A CE2 1 ATOM 1908 C CZ . TYR A 1 250 ? -11.168 -30.078 -32.547 1.00 71.89 ? 246 TYR A CZ 1 ATOM 1909 O OH . TYR A 1 250 ? -11.615 -30.266 -31.258 1.00 72.71 ? 246 TYR A OH 1 ATOM 1910 N N . THR A 1 251 ? -10.247 -26.438 -37.486 1.00 61.86 ? 247 THR A N 1 ATOM 1911 C CA . THR A 1 251 ? -10.945 -25.162 -37.376 1.00 65.33 ? 247 THR A CA 1 ATOM 1912 C C . THR A 1 251 ? -12.451 -25.325 -37.548 1.00 67.93 ? 247 THR A C 1 ATOM 1913 O O . THR A 1 251 ? -12.917 -26.107 -38.378 1.00 78.12 ? 247 THR A O 1 ATOM 1914 C CB . THR A 1 251 ? -10.430 -24.150 -38.417 1.00 67.18 ? 247 THR A CB 1 ATOM 1915 O OG1 . THR A 1 251 ? -9.006 -24.036 -38.306 1.00 79.24 ? 247 THR A OG1 1 ATOM 1916 C CG2 . THR A 1 251 ? -11.073 -22.779 -38.201 1.00 74.65 ? 247 THR A CG2 1 ATOM 1917 N N . ARG A 1 252 ? -13.201 -24.577 -36.745 1.00 55.98 ? 248 ARG A N 1 ATOM 1918 C CA . ARG A 1 252 ? -14.655 -24.567 -36.813 1.00 60.89 ? 248 ARG A CA 1 ATOM 1919 C C . ARG A 1 252 ? -15.151 -23.127 -36.763 1.00 67.75 ? 248 ARG A C 1 ATOM 1920 O O . ARG A 1 252 ? -14.859 -22.395 -35.815 1.00 60.07 ? 248 ARG A O 1 ATOM 1921 C CB . ARG A 1 252 ? -15.263 -25.370 -35.663 1.00 76.34 ? 248 ARG A CB 1 ATOM 1922 C CG . ARG A 1 252 ? -14.624 -26.728 -35.422 1.00 72.92 ? 248 ARG A CG 1 ATOM 1923 C CD . ARG A 1 252 ? -14.777 -27.134 -33.974 1.00 84.07 ? 248 ARG A CD 1 ATOM 1924 N NE . ARG A 1 252 ? -16.143 -27.530 -33.646 1.00 95.89 ? 248 ARG A NE 1 ATOM 1925 C CZ . ARG A 1 252 ? -16.597 -28.781 -33.686 1.00 110.52 ? 248 ARG A CZ 1 ATOM 1926 N NH1 . ARG A 1 252 ? -15.799 -29.781 -34.043 1.00 104.35 ? 248 ARG A NH1 1 ATOM 1927 N NH2 . ARG A 1 252 ? -17.858 -29.033 -33.366 1.00 110.31 ? 248 ARG A NH2 1 ATOM 1928 N N . TRP A 1 253 ? -15.898 -22.727 -37.787 1.00 68.50 ? 249 TRP A N 1 ATOM 1929 C CA . TRP A 1 253 ? -16.442 -21.376 -37.866 1.00 50.35 ? 249 TRP A CA 1 ATOM 1930 C C . TRP A 1 253 ? -17.881 -21.335 -37.368 1.00 50.46 ? 249 TRP A C 1 ATOM 1931 O O . TRP A 1 253 ? -18.695 -22.188 -37.724 1.00 56.63 ? 249 TRP A O 1 ATOM 1932 C CB . TRP A 1 253 ? -16.370 -20.853 -39.301 1.00 57.37 ? 249 TRP A CB 1 ATOM 1933 C CG . TRP A 1 253 ? -15.077 -20.157 -39.612 1.00 64.49 ? 249 TRP A CG 1 ATOM 1934 C CD1 . TRP A 1 253 ? -14.036 -20.649 -40.343 1.00 58.30 ? 249 TRP A CD1 1 ATOM 1935 C CD2 . TRP A 1 253 ? -14.688 -18.843 -39.195 1.00 63.17 ? 249 TRP A CD2 1 ATOM 1936 N NE1 . TRP A 1 253 ? -13.025 -19.722 -40.410 1.00 53.53 ? 249 TRP A NE1 1 ATOM 1937 C CE2 . TRP A 1 253 ? -13.400 -18.604 -39.712 1.00 59.85 ? 249 TRP A CE2 1 ATOM 1938 C CE3 . TRP A 1 253 ? -15.304 -17.845 -38.434 1.00 54.23 ? 249 TRP A CE3 1 ATOM 1939 C CZ2 . TRP A 1 253 ? -12.718 -17.411 -39.494 1.00 58.00 ? 249 TRP A CZ2 1 ATOM 1940 C CZ3 . TRP A 1 253 ? -14.625 -16.663 -38.220 1.00 51.14 ? 249 TRP A CZ3 1 ATOM 1941 C CH2 . TRP A 1 253 ? -13.347 -16.455 -38.748 1.00 56.60 ? 249 TRP A CH2 1 ATOM 1942 N N . TYR A 1 254 ? -18.182 -20.338 -36.543 1.00 51.60 ? 250 TYR A N 1 ATOM 1943 C CA . TYR A 1 254 ? -19.526 -20.153 -36.007 1.00 49.54 ? 250 TYR A CA 1 ATOM 1944 C C . TYR A 1 254 ? -20.002 -18.726 -36.228 1.00 51.75 ? 250 TYR A C 1 ATOM 1945 O O . TYR A 1 254 ? -19.196 -17.804 -36.364 1.00 55.90 ? 250 TYR A O 1 ATOM 1946 C CB . TYR A 1 254 ? -19.566 -20.489 -34.516 1.00 51.80 ? 250 TYR A CB 1 ATOM 1947 C CG . TYR A 1 254 ? -19.304 -21.947 -34.218 1.00 67.73 ? 250 TYR A CG 1 ATOM 1948 C CD1 . TYR A 1 254 ? -18.012 -22.449 -34.195 1.00 73.38 ? 250 TYR A CD1 1 ATOM 1949 C CD2 . TYR A 1 254 ? -20.350 -22.822 -33.961 1.00 70.34 ? 250 TYR A CD2 1 ATOM 1950 C CE1 . TYR A 1 254 ? -17.768 -23.781 -33.926 1.00 75.84 ? 250 TYR A CE1 1 ATOM 1951 C CE2 . TYR A 1 254 ? -20.116 -24.155 -33.691 1.00 73.77 ? 250 TYR A CE2 1 ATOM 1952 C CZ . TYR A 1 254 ? -18.824 -24.630 -33.674 1.00 74.12 ? 250 TYR A CZ 1 ATOM 1953 O OH . TYR A 1 254 ? -18.587 -25.958 -33.405 1.00 92.81 ? 250 TYR A OH 1 ATOM 1954 N N . LYS A 1 255 ? -21.319 -18.557 -36.266 1.00 54.78 ? 251 LYS A N 1 ATOM 1955 C CA . LYS A 1 255 ? -21.928 -17.242 -36.399 1.00 50.93 ? 251 LYS A CA 1 ATOM 1956 C C . LYS A 1 255 ? -22.883 -16.994 -35.239 1.00 61.13 ? 251 LYS A C 1 ATOM 1957 O O . LYS A 1 255 ? -23.705 -17.847 -34.904 1.00 72.47 ? 251 LYS A O 1 ATOM 1958 C CB . LYS A 1 255 ? -22.664 -17.120 -37.731 1.00 43.82 ? 251 LYS A CB 1 ATOM 1959 C CG . LYS A 1 255 ? -23.270 -15.751 -37.960 1.00 46.98 ? 251 LYS A CG 1 ATOM 1960 C CD . LYS A 1 255 ? -23.965 -15.672 -39.299 1.00 45.69 ? 251 LYS A CD 1 ATOM 1961 C CE . LYS A 1 255 ? -24.772 -14.395 -39.418 1.00 54.25 ? 251 LYS A CE 1 ATOM 1962 N NZ . LYS A 1 255 ? -25.649 -14.406 -40.618 1.00 66.93 ? 251 LYS A NZ 1 ATOM 1963 N N . PHE A 1 256 ? -22.766 -15.819 -34.629 1.00 45.14 ? 252 PHE A N 1 ATOM 1964 C CA . PHE A 1 256 ? -23.585 -15.475 -33.475 1.00 51.93 ? 252 PHE A CA 1 ATOM 1965 C C . PHE A 1 256 ? -25.004 -15.105 -33.876 1.00 67.41 ? 252 PHE A C 1 ATOM 1966 O O . PHE A 1 256 ? -25.222 -14.435 -34.885 1.00 66.63 ? 252 PHE A O 1 ATOM 1967 C CB . PHE A 1 256 ? -22.962 -14.315 -32.699 1.00 66.03 ? 252 PHE A CB 1 ATOM 1968 C CG . PHE A 1 256 ? -22.132 -14.748 -31.525 1.00 66.41 ? 252 PHE A CG 1 ATOM 1969 C CD1 . PHE A 1 256 ? -22.735 -15.163 -30.351 1.00 66.33 ? 252 PHE A CD1 1 ATOM 1970 C CD2 . PHE A 1 256 ? -20.751 -14.738 -31.594 1.00 59.69 ? 252 PHE A CD2 1 ATOM 1971 C CE1 . PHE A 1 256 ? -21.976 -15.562 -29.271 1.00 78.57 ? 252 PHE A CE1 1 ATOM 1972 C CE2 . PHE A 1 256 ? -19.988 -15.136 -30.516 1.00 64.66 ? 252 PHE A CE2 1 ATOM 1973 C CZ . PHE A 1 256 ? -20.600 -15.549 -29.354 1.00 78.26 ? 252 PHE A CZ 1 ATOM 1974 N N . ILE A 1 257 ? -25.966 -15.552 -33.077 1.00 74.12 ? 253 ILE A N 1 ATOM 1975 C CA . ILE A 1 257 ? -27.341 -15.101 -33.221 1.00 69.64 ? 253 ILE A CA 1 ATOM 1976 C C . ILE A 1 257 ? -27.457 -13.759 -32.508 1.00 72.15 ? 253 ILE A C 1 ATOM 1977 O O . ILE A 1 257 ? -26.956 -13.587 -31.396 1.00 72.88 ? 253 ILE A O 1 ATOM 1978 C CB . ILE A 1 257 ? -28.343 -16.127 -32.665 1.00 69.12 ? 253 ILE A CB 1 ATOM 1979 C CG1 . ILE A 1 257 ? -28.273 -17.406 -33.505 1.00 72.91 ? 253 ILE A CG1 1 ATOM 1980 C CG2 . ILE A 1 257 ? -29.762 -15.558 -32.677 1.00 68.82 ? 253 ILE A CG2 1 ATOM 1981 C CD1 . ILE A 1 257 ? -29.078 -18.559 -32.962 1.00 83.60 ? 253 ILE A CD1 1 ATOM 1982 N N . GLU A 1 258 ? -28.126 -12.817 -33.162 1.00 72.63 ? 254 GLU A N 1 ATOM 1983 C CA . GLU A 1 258 ? -28.040 -11.403 -32.805 1.00 74.98 ? 254 GLU A CA 1 ATOM 1984 C C . GLU A 1 258 ? -28.536 -11.090 -31.395 1.00 83.04 ? 254 GLU A C 1 ATOM 1985 O O . GLU A 1 258 ? -29.630 -11.495 -30.998 1.00 85.08 ? 254 GLU A O 1 ATOM 1986 C CB . GLU A 1 258 ? -28.823 -10.562 -33.818 1.00 76.98 ? 254 GLU A CB 1 ATOM 1987 C CG . GLU A 1 258 ? -28.216 -10.548 -35.221 1.00 85.56 ? 254 GLU A CG 1 ATOM 1988 C CD . GLU A 1 258 ? -28.409 -11.853 -35.971 1.00 88.20 ? 254 GLU A CD 1 ATOM 1989 O OE1 . GLU A 1 258 ? -29.212 -12.694 -35.515 1.00 89.51 ? 254 GLU A OE1 1 ATOM 1990 O OE2 . GLU A 1 258 ? -27.752 -12.042 -37.017 1.00 87.36 ? 254 GLU A OE2 1 ATOM 1991 N N . GLY A 1 259 ? -27.710 -10.365 -30.645 1.00 73.92 ? 255 GLY A N 1 ATOM 1992 C CA . GLY A 1 259 ? -28.094 -9.841 -29.347 1.00 81.54 ? 255 GLY A CA 1 ATOM 1993 C C . GLY A 1 259 ? -28.214 -10.885 -28.254 1.00 89.56 ? 255 GLY A C 1 ATOM 1994 O O . GLY A 1 259 ? -28.837 -10.631 -27.222 1.00 87.45 ? 255 GLY A O 1 ATOM 1995 N N . THR A 1 260 ? -27.620 -12.056 -28.473 1.00 85.81 ? 256 THR A N 1 ATOM 1996 C CA . THR A 1 260 ? -27.672 -13.134 -27.488 1.00 78.42 ? 256 THR A CA 1 ATOM 1997 C C . THR A 1 260 ? -26.355 -13.899 -27.393 1.00 90.85 ? 256 THR A C 1 ATOM 1998 O O . THR A 1 260 ? -25.477 -13.768 -28.248 1.00 87.86 ? 256 THR A O 1 ATOM 1999 C CB . THR A 1 260 ? -28.807 -14.130 -27.801 1.00 86.96 ? 256 THR A CB 1 ATOM 2000 O OG1 . THR A 1 260 ? -28.697 -14.587 -29.154 1.00 79.57 ? 256 THR A OG1 1 ATOM 2001 C CG2 . THR A 1 260 ? -30.162 -13.470 -27.594 1.00 100.99 ? 256 THR A CG2 1 ATOM 2002 N N . THR A 1 261 ? -26.236 -14.697 -26.336 1.00 100.86 ? 257 THR A N 1 ATOM 2003 C CA . THR A 1 261 ? -25.019 -15.448 -26.049 1.00 98.41 ? 257 THR A CA 1 ATOM 2004 C C . THR A 1 261 ? -24.997 -16.783 -26.794 1.00 82.76 ? 257 THR A C 1 ATOM 2005 O O . THR A 1 261 ? -24.044 -17.553 -26.675 1.00 86.27 ? 257 THR A O 1 ATOM 2006 C CB . THR A 1 261 ? -24.882 -15.711 -24.531 1.00 100.39 ? 257 THR A CB 1 ATOM 2007 O OG1 . THR A 1 261 ? -25.413 -14.600 -23.798 1.00 90.29 ? 257 THR A OG1 1 ATOM 2008 C CG2 . THR A 1 261 ? -23.425 -15.922 -24.139 1.00 96.69 ? 257 THR A CG2 1 ATOM 2009 N N . ARG A 1 262 ? -26.045 -17.050 -27.569 1.00 78.54 ? 258 ARG A N 1 ATOM 2010 C CA . ARG A 1 262 ? -26.188 -18.335 -28.246 1.00 85.63 ? 258 ARG A CA 1 ATOM 2011 C C . ARG A 1 262 ? -25.573 -18.303 -29.642 1.00 78.55 ? 258 ARG A C 1 ATOM 2012 O O . ARG A 1 262 ? -25.851 -17.401 -30.434 1.00 74.85 ? 258 ARG A O 1 ATOM 2013 C CB . ARG A 1 262 ? -27.664 -18.727 -28.321 1.00 86.67 ? 258 ARG A CB 1 ATOM 2014 C CG . ARG A 1 262 ? -28.332 -18.783 -26.956 1.00 89.28 ? 258 ARG A CG 1 ATOM 2015 C CD . ARG A 1 262 ? -29.738 -19.357 -27.020 1.00 81.47 ? 258 ARG A CD 1 ATOM 2016 N NE . ARG A 1 262 ? -30.680 -18.454 -27.679 1.00 88.33 ? 258 ARG A NE 1 ATOM 2017 C CZ . ARG A 1 262 ? -30.948 -18.453 -28.982 1.00 84.90 ? 258 ARG A CZ 1 ATOM 2018 N NH1 . ARG A 1 262 ? -30.349 -19.308 -29.801 1.00 81.68 ? 258 ARG A NH1 1 ATOM 2019 N NH2 . ARG A 1 262 ? -31.824 -17.587 -29.471 1.00 90.25 ? 258 ARG A NH2 1 ATOM 2020 N N . LYS A 1 263 ? -24.736 -19.295 -29.932 1.00 73.99 ? 259 LYS A N 1 ATOM 2021 C CA . LYS A 1 263 ? -24.025 -19.362 -31.204 1.00 69.56 ? 259 LYS A CA 1 ATOM 2022 C C . LYS A 1 263 ? -24.708 -20.296 -32.190 1.00 64.91 ? 259 LYS A C 1 ATOM 2023 O O . LYS A 1 263 ? -25.706 -20.941 -31.869 1.00 71.17 ? 259 LYS A O 1 ATOM 2024 C CB . LYS A 1 263 ? -22.587 -19.834 -30.984 1.00 67.87 ? 259 LYS A CB 1 ATOM 2025 C CG . LYS A 1 263 ? -21.760 -18.931 -30.093 1.00 72.90 ? 259 LYS A CG 1 ATOM 2026 C CD . LYS A 1 263 ? -20.359 -19.483 -29.897 1.00 71.99 ? 259 LYS A CD 1 ATOM 2027 C CE . LYS A 1 263 ? -20.355 -20.724 -29.017 1.00 69.34 ? 259 LYS A CE 1 ATOM 2028 N NZ . LYS A 1 263 ? -18.970 -21.173 -28.708 1.00 68.49 ? 259 LYS A NZ 1 ATOM 2029 N N . GLN A 1 264 ? -24.154 -20.360 -33.396 1.00 63.30 ? 260 GLN A N 1 ATOM 2030 C CA . GLN A 1 264 ? -24.582 -21.329 -34.392 1.00 61.47 ? 260 GLN A CA 1 ATOM 2031 C C . GLN A 1 264 ? -23.435 -21.624 -35.353 1.00 61.34 ? 260 GLN A C 1 ATOM 2032 O O . GLN A 1 264 ? -22.616 -20.750 -35.636 1.00 67.41 ? 260 GLN A O 1 ATOM 2033 C CB . GLN A 1 264 ? -25.807 -20.821 -35.150 1.00 59.31 ? 260 GLN A CB 1 ATOM 2034 C CG . GLN A 1 264 ? -26.321 -21.799 -36.193 1.00 65.76 ? 260 GLN A CG 1 ATOM 2035 C CD . GLN A 1 264 ? -27.835 -21.901 -36.212 1.00 72.29 ? 260 GLN A CD 1 ATOM 2036 O OE1 . GLN A 1 264 ? -28.542 -20.958 -35.852 1.00 60.47 ? 260 GLN A OE1 1 ATOM 2037 N NE2 . GLN A 1 264 ? -28.342 -23.055 -36.628 1.00 86.52 ? 260 GLN A NE2 1 ATOM 2038 N N . ALA A 1 265 ? -23.383 -22.854 -35.853 1.00 59.13 ? 261 ALA A N 1 ATOM 2039 C CA . ALA A 1 265 ? -22.308 -23.271 -36.746 1.00 44.69 ? 261 ALA A CA 1 ATOM 2040 C C . ALA A 1 265 ? -22.573 -22.814 -38.174 1.00 42.41 ? 261 ALA A C 1 ATOM 2041 O O . ALA A 1 265 ? -23.721 -22.745 -38.614 1.00 44.70 ? 261 ALA A O 1 ATOM 2042 C CB . ALA A 1 265 ? -22.134 -24.781 -36.697 1.00 51.25 ? 261 ALA A CB 1 ATOM 2043 N N . VAL A 1 266 ? -21.499 -22.501 -38.892 1.00 47.20 ? 262 VAL A N 1 ATOM 2044 C CA . VAL A 1 266 ? -21.604 -22.022 -40.265 1.00 52.54 ? 262 VAL A CA 1 ATOM 2045 C C . VAL A 1 266 ? -21.784 -23.190 -41.224 1.00 43.52 ? 262 VAL A C 1 ATOM 2046 O O . VAL A 1 266 ? -21.016 -24.153 -41.202 1.00 46.87 ? 262 VAL A O 1 ATOM 2047 C CB . VAL A 1 266 ? -20.361 -21.204 -40.671 1.00 44.89 ? 262 VAL A CB 1 ATOM 2048 C CG1 . VAL A 1 266 ? -20.462 -20.747 -42.132 1.00 38.88 ? 262 VAL A CG1 1 ATOM 2049 C CG2 . VAL A 1 266 ? -20.199 -20.012 -39.736 1.00 45.84 ? 262 VAL A CG2 1 ATOM 2050 N N . VAL A 1 267 ? -22.807 -23.094 -42.065 1.00 42.14 ? 263 VAL A N 1 ATOM 2051 C CA . VAL A 1 267 ? -23.105 -24.135 -43.038 1.00 52.69 ? 263 VAL A CA 1 ATOM 2052 C C . VAL A 1 267 ? -22.324 -23.885 -44.324 1.00 46.53 ? 263 VAL A C 1 ATOM 2053 O O . VAL A 1 267 ? -22.454 -22.832 -44.949 1.00 45.40 ? 263 VAL A O 1 ATOM 2054 C CB . VAL A 1 267 ? -24.615 -24.201 -43.341 1.00 35.80 ? 263 VAL A CB 1 ATOM 2055 C CG1 . VAL A 1 267 ? -24.915 -25.302 -44.358 1.00 24.69 ? 263 VAL A CG1 1 ATOM 2056 C CG2 . VAL A 1 267 ? -25.394 -24.428 -42.048 1.00 20.65 ? 263 VAL A CG2 1 ATOM 2057 N N . LEU A 1 268 ? -21.509 -24.863 -44.708 1.00 43.59 ? 264 LEU A N 1 ATOM 2058 C CA . LEU A 1 268 ? -20.683 -24.754 -45.904 1.00 41.91 ? 264 LEU A CA 1 ATOM 2059 C C . LEU A 1 268 ? -21.439 -25.203 -47.147 1.00 45.70 ? 264 LEU A C 1 ATOM 2060 O O . LEU A 1 268 ? -22.101 -26.242 -47.148 1.00 50.05 ? 264 LEU A O 1 ATOM 2061 C CB . LEU A 1 268 ? -19.406 -25.575 -45.745 1.00 39.29 ? 264 LEU A CB 1 ATOM 2062 C CG . LEU A 1 268 ? -18.287 -24.883 -44.968 1.00 47.49 ? 264 LEU A CG 1 ATOM 2063 C CD1 . LEU A 1 268 ? -18.686 -24.617 -43.518 1.00 37.20 ? 264 LEU A CD1 1 ATOM 2064 C CD2 . LEU A 1 268 ? -17.028 -25.725 -45.042 1.00 55.84 ? 264 LEU A CD2 1 ATOM 2065 N N . ASN A 1 269 ? -21.327 -24.401 -48.201 1.00 48.16 ? 265 ASN A N 1 ATOM 2066 C CA . ASN A 1 269 ? -22.006 -24.649 -49.464 1.00 43.56 ? 265 ASN A CA 1 ATOM 2067 C C . ASN A 1 269 ? -20.993 -24.652 -50.601 1.00 45.64 ? 265 ASN A C 1 ATOM 2068 O O . ASN A 1 269 ? -19.786 -24.623 -50.364 1.00 58.26 ? 265 ASN A O 1 ATOM 2069 C CB . ASN A 1 269 ? -23.080 -23.586 -49.718 1.00 50.12 ? 265 ASN A CB 1 ATOM 2070 C CG . ASN A 1 269 ? -23.916 -23.286 -48.485 1.00 55.14 ? 265 ASN A CG 1 ATOM 2071 O OD1 . ASN A 1 269 ? -24.117 -24.146 -47.629 1.00 61.07 ? 265 ASN A OD1 1 ATOM 2072 N ND2 . ASN A 1 269 ? -24.414 -22.056 -48.395 1.00 48.12 ? 265 ASN A ND2 1 ATOM 2073 N N . ASP A 1 270 ? -21.481 -24.715 -51.835 1.00 43.39 ? 266 ASP A N 1 ATOM 2074 C CA . ASP A 1 270 ? -20.639 -24.426 -52.991 1.00 52.42 ? 266 ASP A CA 1 ATOM 2075 C C . ASP A 1 270 ? -20.438 -22.913 -53.083 1.00 57.13 ? 266 ASP A C 1 ATOM 2076 O O . ASP A 1 270 ? -19.631 -22.423 -53.876 1.00 57.17 ? 266 ASP A O 1 ATOM 2077 C CB . ASP A 1 270 ? -21.258 -24.980 -54.277 1.00 51.27 ? 266 ASP A CB 1 ATOM 2078 C CG . ASP A 1 270 ? -22.709 -24.586 -54.443 1.00 72.68 ? 266 ASP A CG 1 ATOM 2079 O OD1 . ASP A 1 270 ? -23.342 -24.206 -53.434 1.00 83.19 ? 266 ASP A OD1 1 ATOM 2080 O OD2 . ASP A 1 270 ? -23.220 -24.666 -55.580 1.00 76.65 ? 266 ASP A OD2 1 ATOM 2081 N N . ARG A 1 271 ? -21.189 -22.187 -52.257 1.00 50.57 ? 267 ARG A N 1 ATOM 2082 C CA . ARG A 1 271 ? -21.026 -20.749 -52.086 1.00 46.14 ? 267 ARG A CA 1 ATOM 2083 C C . ARG A 1 271 ? -20.033 -20.478 -50.960 1.00 40.70 ? 267 ARG A C 1 ATOM 2084 O O . ARG A 1 271 ? -18.965 -19.906 -51.184 1.00 52.08 ? 267 ARG A O 1 ATOM 2085 C CB . ARG A 1 271 ? -22.373 -20.091 -51.778 1.00 58.71 ? 267 ARG A CB 1 ATOM 2086 C CG . ARG A 1 271 ? -22.414 -18.596 -52.039 1.00 50.79 ? 267 ARG A CG 1 ATOM 2087 C CD . ARG A 1 271 ? -23.752 -18.002 -51.631 1.00 43.99 ? 267 ARG A CD 1 ATOM 2088 N NE . ARG A 1 271 ? -23.845 -17.800 -50.186 1.00 39.70 ? 267 ARG A NE 1 ATOM 2089 C CZ . ARG A 1 271 ? -23.387 -16.728 -49.546 1.00 47.74 ? 267 ARG A CZ 1 ATOM 2090 N NH1 . ARG A 1 271 ? -22.797 -15.748 -50.212 1.00 42.49 ? 267 ARG A NH1 1 ATOM 2091 N NH2 . ARG A 1 271 ? -23.517 -16.635 -48.232 1.00 45.00 ? 267 ARG A NH2 1 ATOM 2092 N N . VAL A 1 272 ? -20.396 -20.894 -49.748 1.00 33.81 ? 268 VAL A N 1 ATOM 2093 C CA . VAL A 1 272 ? -19.541 -20.714 -48.578 1.00 32.68 ? 268 VAL A CA 1 ATOM 2094 C C . VAL A 1 272 ? -18.545 -21.867 -48.457 1.00 52.39 ? 268 VAL A C 1 ATOM 2095 O O . VAL A 1 272 ? -18.936 -23.021 -48.285 1.00 67.11 ? 268 VAL A O 1 ATOM 2096 C CB . VAL A 1 272 ? -20.369 -20.617 -47.280 1.00 28.80 ? 268 VAL A CB 1 ATOM 2097 C CG1 . VAL A 1 272 ? -19.463 -20.333 -46.084 1.00 34.55 ? 268 VAL A CG1 1 ATOM 2098 C CG2 . VAL A 1 272 ? -21.436 -19.538 -47.414 1.00 42.88 ? 268 VAL A CG2 1 ATOM 2099 N N . LYS A 1 273 ? -17.257 -21.538 -48.523 1.00 51.09 ? 269 LYS A N 1 ATOM 2100 C CA . LYS A 1 273 ? -16.191 -22.536 -48.540 1.00 41.98 ? 269 LYS A CA 1 ATOM 2101 C C . LYS A 1 273 ? -15.242 -22.366 -47.364 1.00 43.82 ? 269 LYS A C 1 ATOM 2102 O O . LYS A 1 273 ? -15.163 -21.291 -46.772 1.00 42.14 ? 269 LYS A O 1 ATOM 2103 C CB . LYS A 1 273 ? -15.399 -22.445 -49.843 1.00 47.23 ? 269 LYS A CB 1 ATOM 2104 C CG . LYS A 1 273 ? -16.133 -22.981 -51.053 1.00 61.14 ? 269 LYS A CG 1 ATOM 2105 C CD . LYS A 1 273 ? -15.820 -24.448 -51.272 1.00 82.46 ? 269 LYS A CD 1 ATOM 2106 C CE . LYS A 1 273 ? -16.387 -24.939 -52.589 1.00 93.74 ? 269 LYS A CE 1 ATOM 2107 N NZ . LYS A 1 273 ? -16.007 -26.349 -52.867 1.00 93.26 ? 269 LYS A NZ 1 ATOM 2108 N N . GLN A 1 274 ? -14.520 -23.433 -47.035 1.00 51.36 ? 270 GLN A N 1 ATOM 2109 C CA . GLN A 1 274 ? -13.506 -23.374 -45.992 1.00 42.02 ? 270 GLN A CA 1 ATOM 2110 C C . GLN A 1 274 ? -12.192 -23.980 -46.464 1.00 41.65 ? 270 GLN A C 1 ATOM 2111 O O . GLN A 1 274 ? -12.167 -25.048 -47.075 1.00 58.80 ? 270 GLN A O 1 ATOM 2112 C CB . GLN A 1 274 ? -13.980 -24.088 -44.729 1.00 40.78 ? 270 GLN A CB 1 ATOM 2113 C CG . GLN A 1 274 ? -12.969 -24.030 -43.592 1.00 32.56 ? 270 GLN A CG 1 ATOM 2114 C CD . GLN A 1 274 ? -13.568 -24.394 -42.245 1.00 38.14 ? 270 GLN A CD 1 ATOM 2115 O OE1 . GLN A 1 274 ? -14.776 -24.598 -42.121 1.00 55.93 ? 270 GLN A OE1 1 ATOM 2116 N NE2 . GLN A 1 274 ? -12.722 -24.473 -41.225 1.00 42.47 ? 270 GLN A NE2 1 ATOM 2117 N N . VAL A 1 275 ? -11.104 -23.276 -46.172 1.00 48.78 ? 271 VAL A N 1 ATOM 2118 C CA . VAL A 1 275 ? -9.758 -23.730 -46.498 1.00 48.37 ? 271 VAL A CA 1 ATOM 2119 C C . VAL A 1 275 ? -8.873 -23.509 -45.281 1.00 45.97 ? 271 VAL A C 1 ATOM 2120 O O . VAL A 1 275 ? -8.712 -22.375 -44.835 1.00 46.79 ? 271 VAL A O 1 ATOM 2121 C CB . VAL A 1 275 ? -9.176 -22.980 -47.708 1.00 38.58 ? 271 VAL A CB 1 ATOM 2122 C CG1 . VAL A 1 275 ? -7.884 -23.642 -48.168 1.00 50.13 ? 271 VAL A CG1 1 ATOM 2123 C CG2 . VAL A 1 275 ? -10.192 -22.930 -48.839 1.00 52.69 ? 271 VAL A CG2 1 ATOM 2124 N N . SER A 1 276 ? -8.298 -24.585 -44.748 1.00 53.12 ? 272 SER A N 1 ATOM 2125 C CA . SER A 1 276 ? -7.594 -24.508 -43.472 1.00 63.61 ? 272 SER A CA 1 ATOM 2126 C C . SER A 1 276 ? -8.548 -23.886 -42.451 1.00 56.24 ? 272 SER A C 1 ATOM 2127 O O . SER A 1 276 ? -9.585 -24.472 -42.138 1.00 53.69 ? 272 SER A O 1 ATOM 2128 C CB . SER A 1 276 ? -6.298 -23.701 -43.601 1.00 68.99 ? 272 SER A CB 1 ATOM 2129 O OG . SER A 1 276 ? -5.688 -23.507 -42.337 1.00 83.29 ? 272 SER A OG 1 ATOM 2130 N N . GLY A 1 277 ? -8.199 -22.708 -41.938 1.00 58.13 ? 273 GLY A N 1 ATOM 2131 C CA . GLY A 1 277 ? -9.088 -21.955 -41.070 1.00 64.29 ? 273 GLY A CA 1 ATOM 2132 C C . GLY A 1 277 ? -9.751 -20.802 -41.808 1.00 59.03 ? 273 GLY A C 1 ATOM 2133 O O . GLY A 1 277 ? -10.511 -20.033 -41.219 1.00 58.79 ? 273 GLY A O 1 ATOM 2134 N N . THR A 1 278 ? -9.464 -20.688 -43.103 1.00 48.50 ? 274 THR A N 1 ATOM 2135 C CA . THR A 1 278 ? -9.965 -19.583 -43.918 1.00 40.11 ? 274 THR A CA 1 ATOM 2136 C C . THR A 1 278 ? -11.402 -19.817 -44.374 1.00 47.77 ? 274 THR A C 1 ATOM 2137 O O . THR A 1 278 ? -11.696 -20.808 -45.039 1.00 61.65 ? 274 THR A O 1 ATOM 2138 C CB . THR A 1 278 ? -9.080 -19.359 -45.169 1.00 45.12 ? 274 THR A CB 1 ATOM 2139 O OG1 . THR A 1 278 ? -7.726 -19.118 -44.765 1.00 53.88 ? 274 THR A OG1 1 ATOM 2140 C CG2 . THR A 1 278 ? -9.585 -18.175 -46.000 1.00 56.34 ? 274 THR A CG2 1 ATOM 2141 N N . LEU A 1 279 ? -12.287 -18.888 -44.020 1.00 42.46 ? 275 LEU A N 1 ATOM 2142 C CA . LEU A 1 279 ? -13.683 -18.941 -44.441 1.00 32.82 ? 275 LEU A CA 1 ATOM 2143 C C . LEU A 1 279 ? -13.899 -18.027 -45.645 1.00 37.58 ? 275 LEU A C 1 ATOM 2144 O O . LEU A 1 279 ? -13.409 -16.898 -45.666 1.00 41.21 ? 275 LEU A O 1 ATOM 2145 C CB . LEU A 1 279 ? -14.605 -18.537 -43.288 1.00 41.95 ? 275 LEU A CB 1 ATOM 2146 C CG . LEU A 1 279 ? -16.110 -18.513 -43.567 1.00 44.88 ? 275 LEU A CG 1 ATOM 2147 C CD1 . LEU A 1 279 ? -16.597 -19.847 -44.119 1.00 53.06 ? 275 LEU A CD1 1 ATOM 2148 C CD2 . LEU A 1 279 ? -16.860 -18.155 -42.296 1.00 42.51 ? 275 LEU A CD2 1 ATOM 2149 N N . ILE A 1 280 ? -14.629 -18.520 -46.643 1.00 45.87 ? 276 ILE A N 1 ATOM 2150 C CA . ILE A 1 280 ? -14.858 -17.772 -47.879 1.00 36.16 ? 276 ILE A CA 1 ATOM 2151 C C . ILE A 1 280 ? -16.356 -17.659 -48.162 1.00 34.47 ? 276 ILE A C 1 ATOM 2152 O O . ILE A 1 280 ? -17.043 -18.654 -48.371 1.00 31.77 ? 276 ILE A O 1 ATOM 2153 C CB . ILE A 1 280 ? -14.135 -18.431 -49.074 1.00 36.78 ? 276 ILE A CB 1 ATOM 2154 C CG1 . ILE A 1 280 ? -12.632 -18.518 -48.791 1.00 43.90 ? 276 ILE A CG1 1 ATOM 2155 C CG2 . ILE A 1 280 ? -14.384 -17.643 -50.359 1.00 33.71 ? 276 ILE A CG2 1 ATOM 2156 C CD1 . ILE A 1 280 ? -11.865 -19.400 -49.758 1.00 59.41 ? 276 ILE A CD1 1 ATOM 2157 N N . ILE A 1 281 ? -16.833 -16.419 -48.159 1.00 37.12 ? 277 ILE A N 1 ATOM 2158 C CA . ILE A 1 281 ? -18.254 -16.078 -48.261 1.00 36.81 ? 277 ILE A CA 1 ATOM 2159 C C . ILE A 1 281 ? -18.664 -15.768 -49.712 1.00 34.25 ? 277 ILE A C 1 ATOM 2160 O O . ILE A 1 281 ? -19.694 -15.144 -49.951 1.00 41.09 ? 277 ILE A O 1 ATOM 2161 C CB . ILE A 1 281 ? -18.607 -14.905 -47.320 1.00 24.75 ? 277 ILE A CB 1 ATOM 2162 C CG1 . ILE A 1 281 ? -17.867 -15.094 -45.989 1.00 36.65 ? 277 ILE A CG1 1 ATOM 2163 C CG2 . ILE A 1 281 ? -20.132 -14.822 -47.086 1.00 35.09 ? 277 ILE A CG2 1 ATOM 2164 C CD1 . ILE A 1 281 ? -18.589 -14.554 -44.763 1.00 33.35 ? 277 ILE A CD1 1 ATOM 2165 N N . LYS A 1 282 ? -17.841 -16.188 -50.671 1.00 35.86 ? 278 LYS A N 1 ATOM 2166 C CA . LYS A 1 282 ? -17.890 -15.698 -52.054 1.00 43.10 ? 278 LYS A CA 1 ATOM 2167 C C . LYS A 1 282 ? -19.303 -15.555 -52.631 1.00 44.82 ? 278 LYS A C 1 ATOM 2168 O O . LYS A 1 282 ? -20.184 -16.373 -52.365 1.00 41.91 ? 278 LYS A O 1 ATOM 2169 C CB . LYS A 1 282 ? -17.085 -16.644 -52.956 1.00 58.02 ? 278 LYS A CB 1 ATOM 2170 C CG . LYS A 1 282 ? -17.924 -17.486 -53.916 1.00 66.53 ? 278 LYS A CG 1 ATOM 2171 C CD . LYS A 1 282 ? -17.070 -18.489 -54.650 1.00 66.99 ? 278 LYS A CD 1 ATOM 2172 C CE . LYS A 1 282 ? -17.816 -19.107 -55.822 1.00 76.22 ? 278 LYS A CE 1 ATOM 2173 N NZ . LYS A 1 282 ? -18.041 -18.129 -56.925 1.00 91.74 ? 278 LYS A NZ 1 ATOM 2174 N N . ASP A 1 283 ? -19.499 -14.484 -53.403 1.00 50.94 ? 279 ASP A N 1 ATOM 2175 C CA . ASP A 1 283 ? -20.820 -14.062 -53.881 1.00 54.21 ? 279 ASP A CA 1 ATOM 2176 C C . ASP A 1 283 ? -21.714 -13.748 -52.685 1.00 53.76 ? 279 ASP A C 1 ATOM 2177 O O . ASP A 1 283 ? -22.669 -14.469 -52.391 1.00 55.08 ? 279 ASP A O 1 ATOM 2178 C CB . ASP A 1 283 ? -21.457 -15.127 -54.783 1.00 57.49 ? 279 ASP A CB 1 ATOM 2179 C CG . ASP A 1 283 ? -20.765 -15.240 -56.128 1.00 57.97 ? 279 ASP A CG 1 ATOM 2180 O OD1 . ASP A 1 283 ? -20.462 -14.191 -56.734 1.00 53.08 ? 279 ASP A OD1 1 ATOM 2181 O OD2 . ASP A 1 283 ? -20.523 -16.379 -56.583 1.00 67.91 ? 279 ASP A OD2 1 ATOM 2182 N N . ALA A 1 284 ? -21.388 -12.651 -52.006 1.00 46.96 ? 280 ALA A N 1 ATOM 2183 C CA . ALA A 1 284 ? -21.979 -12.332 -50.711 1.00 52.52 ? 280 ALA A CA 1 ATOM 2184 C C . ALA A 1 284 ? -23.339 -11.647 -50.814 1.00 52.92 ? 280 ALA A C 1 ATOM 2185 O O . ALA A 1 284 ? -23.825 -11.343 -51.905 1.00 51.31 ? 280 ALA A O 1 ATOM 2186 C CB . ALA A 1 284 ? -21.016 -11.451 -49.911 1.00 45.56 ? 280 ALA A CB 1 ATOM 2187 N N . VAL A 1 285 ? -23.933 -11.412 -49.648 1.00 48.66 ? 281 VAL A N 1 ATOM 2188 C CA . VAL A 1 285 ? -25.200 -10.706 -49.518 1.00 46.00 ? 281 VAL A CA 1 ATOM 2189 C C . VAL A 1 285 ? -25.211 -10.024 -48.156 1.00 41.27 ? 281 VAL A C 1 ATOM 2190 O O . VAL A 1 285 ? -24.419 -10.373 -47.281 1.00 44.54 ? 281 VAL A O 1 ATOM 2191 C CB . VAL A 1 285 ? -26.422 -11.646 -49.646 1.00 48.27 ? 281 VAL A CB 1 ATOM 2192 C CG1 . VAL A 1 285 ? -26.499 -12.250 -51.043 1.00 48.49 ? 281 VAL A CG1 1 ATOM 2193 C CG2 . VAL A 1 285 ? -26.377 -12.744 -48.589 1.00 50.30 ? 281 VAL A CG2 1 ATOM 2194 N N . VAL A 1 286 ? -26.102 -9.056 -47.977 1.00 43.39 ? 282 VAL A N 1 ATOM 2195 C CA . VAL A 1 286 ? -26.144 -8.275 -46.744 1.00 44.43 ? 282 VAL A CA 1 ATOM 2196 C C . VAL A 1 286 ? -26.354 -9.164 -45.523 1.00 47.34 ? 282 VAL A C 1 ATOM 2197 O O . VAL A 1 286 ? -25.783 -8.921 -44.459 1.00 50.43 ? 282 VAL A O 1 ATOM 2198 C CB . VAL A 1 286 ? -27.265 -7.218 -46.782 1.00 45.31 ? 282 VAL A CB 1 ATOM 2199 C CG1 . VAL A 1 286 ? -27.234 -6.358 -45.518 1.00 35.95 ? 282 VAL A CG1 1 ATOM 2200 C CG2 . VAL A 1 286 ? -27.137 -6.346 -48.027 1.00 42.73 ? 282 VAL A CG2 1 ATOM 2201 N N . GLU A 1 287 ? -27.163 -10.204 -45.689 1.00 64.67 ? 283 GLU A N 1 ATOM 2202 C CA . GLU A 1 287 ? -27.561 -11.054 -44.572 1.00 63.00 ? 283 GLU A CA 1 ATOM 2203 C C . GLU A 1 287 ? -26.414 -11.936 -44.077 1.00 58.40 ? 283 GLU A C 1 ATOM 2204 O O . GLU A 1 287 ? -26.542 -12.609 -43.053 1.00 53.09 ? 283 GLU A O 1 ATOM 2205 C CB . GLU A 1 287 ? -28.759 -11.922 -44.970 1.00 61.32 ? 283 GLU A CB 1 ATOM 2206 C CG . GLU A 1 287 ? -30.055 -11.136 -45.164 1.00 73.69 ? 283 GLU A CG 1 ATOM 2207 C CD . GLU A 1 287 ? -30.048 -10.272 -46.414 1.00 75.18 ? 283 GLU A CD 1 ATOM 2208 O OE1 . GLU A 1 287 ? -29.371 -10.644 -47.397 1.00 70.81 ? 283 GLU A OE1 1 ATOM 2209 O OE2 . GLU A 1 287 ? -30.716 -9.216 -46.410 1.00 68.55 ? 283 GLU A OE2 1 ATOM 2210 N N . ASP A 1 288 ? -25.295 -11.927 -44.798 1.00 60.37 ? 284 ASP A N 1 ATOM 2211 C CA . ASP A 1 288 ? -24.100 -12.650 -44.368 1.00 55.33 ? 284 ASP A CA 1 ATOM 2212 C C . ASP A 1 288 ? -23.454 -11.958 -43.169 1.00 48.53 ? 284 ASP A C 1 ATOM 2213 O O . ASP A 1 288 ? -22.581 -12.522 -42.509 1.00 52.91 ? 284 ASP A O 1 ATOM 2214 C CB . ASP A 1 288 ? -23.083 -12.760 -45.511 1.00 35.06 ? 284 ASP A CB 1 ATOM 2215 C CG . ASP A 1 288 ? -23.509 -13.741 -46.588 1.00 49.49 ? 284 ASP A CG 1 ATOM 2216 O OD1 . ASP A 1 288 ? -24.124 -14.777 -46.255 1.00 58.06 ? 284 ASP A OD1 1 ATOM 2217 O OD2 . ASP A 1 288 ? -23.216 -13.479 -47.774 1.00 42.46 ? 284 ASP A OD2 1 ATOM 2218 N N . SER A 1 289 ? -23.892 -10.733 -42.892 1.00 43.17 ? 285 SER A N 1 ATOM 2219 C CA . SER A 1 289 ? -23.326 -9.938 -41.810 1.00 44.15 ? 285 SER A CA 1 ATOM 2220 C C . SER A 1 289 ? -23.649 -10.545 -40.451 1.00 46.98 ? 285 SER A C 1 ATOM 2221 O O . SER A 1 289 ? -24.648 -11.247 -40.296 1.00 59.36 ? 285 SER A O 1 ATOM 2222 C CB . SER A 1 289 ? -23.851 -8.502 -41.873 1.00 55.25 ? 285 SER A CB 1 ATOM 2223 O OG . SER A 1 289 ? -23.665 -7.942 -43.162 1.00 53.60 ? 285 SER A OG 1 ATOM 2224 N N . GLY A 1 290 ? -22.791 -10.275 -39.474 1.00 42.27 ? 286 GLY A N 1 ATOM 2225 C CA . GLY A 1 290 ? -23.003 -10.738 -38.115 1.00 51.06 ? 286 GLY A CA 1 ATOM 2226 C C . GLY A 1 290 ? -21.680 -10.905 -37.399 1.00 52.74 ? 286 GLY A C 1 ATOM 2227 O O . GLY A 1 290 ? -20.619 -10.702 -37.990 1.00 56.39 ? 286 GLY A O 1 ATOM 2228 N N . LYS A 1 291 ? -21.738 -11.273 -36.124 1.00 56.23 ? 287 LYS A N 1 ATOM 2229 C CA . LYS A 1 291 ? -20.530 -11.587 -35.376 1.00 42.39 ? 287 LYS A CA 1 ATOM 2230 C C . LYS A 1 291 ? -20.168 -13.049 -35.606 1.00 54.94 ? 287 LYS A C 1 ATOM 2231 O O . LYS A 1 291 ? -21.029 -13.926 -35.532 1.00 67.35 ? 287 LYS A O 1 ATOM 2232 C CB . LYS A 1 291 ? -20.716 -11.310 -33.883 1.00 43.35 ? 287 LYS A CB 1 ATOM 2233 C CG . LYS A 1 291 ? -19.542 -10.580 -33.250 1.00 55.76 ? 287 LYS A CG 1 ATOM 2234 C CD . LYS A 1 291 ? -19.394 -10.906 -31.772 1.00 60.75 ? 287 LYS A CD 1 ATOM 2235 C CE . LYS A 1 291 ? -20.632 -10.531 -30.975 1.00 65.75 ? 287 LYS A CE 1 ATOM 2236 N NZ . LYS A 1 291 ? -20.428 -10.746 -29.516 1.00 71.17 ? 287 LYS A NZ 1 ATOM 2237 N N . TYR A 1 292 ? -18.895 -13.302 -35.889 1.00 56.67 ? 288 TYR A N 1 ATOM 2238 C CA . TYR A 1 292 ? -18.409 -14.655 -36.133 1.00 39.25 ? 288 TYR A CA 1 ATOM 2239 C C . TYR A 1 292 ? -17.437 -15.071 -35.046 1.00 39.56 ? 288 TYR A C 1 ATOM 2240 O O . TYR A 1 292 ? -16.807 -14.228 -34.411 1.00 49.26 ? 288 TYR A O 1 ATOM 2241 C CB . TYR A 1 292 ? -17.730 -14.755 -37.498 1.00 39.44 ? 288 TYR A CB 1 ATOM 2242 C CG . TYR A 1 292 ? -18.695 -14.717 -38.660 1.00 40.05 ? 288 TYR A CG 1 ATOM 2243 C CD1 . TYR A 1 292 ? -19.453 -15.828 -38.992 1.00 56.27 ? 288 TYR A CD1 1 ATOM 2244 C CD2 . TYR A 1 292 ? -18.846 -13.573 -39.425 1.00 45.71 ? 288 TYR A CD2 1 ATOM 2245 C CE1 . TYR A 1 292 ? -20.338 -15.799 -40.054 1.00 57.21 ? 288 TYR A CE1 1 ATOM 2246 C CE2 . TYR A 1 292 ? -19.727 -13.536 -40.489 1.00 54.36 ? 288 TYR A CE2 1 ATOM 2247 C CZ . TYR A 1 292 ? -20.469 -14.650 -40.797 1.00 42.93 ? 288 TYR A CZ 1 ATOM 2248 O OH . TYR A 1 292 ? -21.348 -14.614 -41.856 1.00 37.85 ? 288 TYR A OH 1 ATOM 2249 N N . LEU A 1 293 ? -17.332 -16.377 -34.830 1.00 49.64 ? 289 LEU A N 1 ATOM 2250 C CA . LEU A 1 293 ? -16.372 -16.920 -33.881 1.00 46.07 ? 289 LEU A CA 1 ATOM 2251 C C . LEU A 1 293 ? -15.593 -18.058 -34.518 1.00 41.07 ? 289 LEU A C 1 ATOM 2252 O O . LEU A 1 293 ? -16.161 -19.083 -34.895 1.00 49.46 ? 289 LEU A O 1 ATOM 2253 C CB . LEU A 1 293 ? -17.074 -17.408 -32.612 1.00 48.96 ? 289 LEU A CB 1 ATOM 2254 C CG . LEU A 1 293 ? -16.142 -17.898 -31.501 1.00 40.42 ? 289 LEU A CG 1 ATOM 2255 C CD1 . LEU A 1 293 ? -15.341 -16.736 -30.912 1.00 56.06 ? 289 LEU A CD1 1 ATOM 2256 C CD2 . LEU A 1 293 ? -16.932 -18.625 -30.423 1.00 48.35 ? 289 LEU A CD2 1 ATOM 2257 N N . CYS A 1 294 ? -14.286 -17.859 -34.642 1.00 57.98 ? 290 CYS A N 1 ATOM 2258 C CA . CYS A 1 294 ? -13.389 -18.922 -35.062 1.00 53.25 ? 290 CYS A CA 1 ATOM 2259 C C . CYS A 1 294 ? -12.897 -19.655 -33.824 1.00 42.68 ? 290 CYS A C 1 ATOM 2260 O O . CYS A 1 294 ? -12.447 -19.026 -32.868 1.00 41.11 ? 290 CYS A O 1 ATOM 2261 C CB . CYS A 1 294 ? -12.208 -18.372 -35.855 1.00 47.16 ? 290 CYS A CB 1 ATOM 2262 S SG . CYS A 1 294 ? -10.948 -19.613 -36.183 1.00 76.85 ? 290 CYS A SG 1 ATOM 2263 N N . VAL A 1 295 ? -12.983 -20.980 -33.847 1.00 51.72 ? 291 VAL A N 1 ATOM 2264 C CA . VAL A 1 295 ? -12.602 -21.795 -32.699 1.00 58.42 ? 291 VAL A CA 1 ATOM 2265 C C . VAL A 1 295 ? -11.634 -22.888 -33.126 1.00 61.02 ? 291 VAL A C 1 ATOM 2266 O O . VAL A 1 295 ? -11.958 -23.727 -33.968 1.00 71.85 ? 291 VAL A O 1 ATOM 2267 C CB . VAL A 1 295 ? -13.836 -22.429 -32.020 1.00 61.61 ? 291 VAL A CB 1 ATOM 2268 C CG1 . VAL A 1 295 ? -13.415 -23.282 -30.829 1.00 73.78 ? 291 VAL A CG1 1 ATOM 2269 C CG2 . VAL A 1 295 ? -14.811 -21.344 -31.584 1.00 70.27 ? 291 VAL A CG2 1 ATOM 2270 N N . VAL A 1 296 ? -10.444 -22.867 -32.533 1.00 59.07 ? 292 VAL A N 1 ATOM 2271 C CA . VAL A 1 296 ? -9.411 -23.849 -32.834 1.00 76.12 ? 292 VAL A CA 1 ATOM 2272 C C . VAL A 1 296 ? -8.956 -24.539 -31.553 1.00 80.31 ? 292 VAL A C 1 ATOM 2273 O O . VAL A 1 296 ? -8.358 -23.916 -30.674 1.00 83.24 ? 292 VAL A O 1 ATOM 2274 C CB . VAL A 1 296 ? -8.200 -23.195 -33.534 1.00 75.00 ? 292 VAL A CB 1 ATOM 2275 C CG1 . VAL A 1 296 ? -7.128 -24.235 -33.844 1.00 84.23 ? 292 VAL A CG1 1 ATOM 2276 C CG2 . VAL A 1 296 ? -8.648 -22.486 -34.808 1.00 68.80 ? 292 VAL A CG2 1 ATOM 2277 N N . ASN A 1 297 ? -9.249 -25.833 -31.464 1.00 73.45 ? 293 ASN A N 1 ATOM 2278 C CA . ASN A 1 297 ? -8.810 -26.661 -30.348 1.00 79.78 ? 293 ASN A CA 1 ATOM 2279 C C . ASN A 1 297 ? -7.770 -27.670 -30.817 1.00 72.40 ? 293 ASN A C 1 ATOM 2280 O O . ASN A 1 297 ? -7.841 -28.166 -31.943 1.00 67.69 ? 293 ASN A O 1 ATOM 2281 C CB . ASN A 1 297 ? -9.993 -27.402 -29.714 1.00 81.29 ? 293 ASN A CB 1 ATOM 2282 C CG . ASN A 1 297 ? -11.059 -26.465 -29.169 1.00 79.01 ? 293 ASN A CG 1 ATOM 2283 O OD1 . ASN A 1 297 ? -11.681 -25.718 -29.919 1.00 73.93 ? 293 ASN A OD1 1 ATOM 2284 N ND2 . ASN A 1 297 ? -11.283 -26.515 -27.855 1.00 87.36 ? 293 ASN A ND2 1 ATOM 2285 N N . ASN A 1 298 ? -6.800 -27.960 -29.956 1.00 68.92 ? 294 ASN A N 1 ATOM 2286 C CA . ASN A 1 298 ? -5.873 -29.061 -30.187 1.00 74.36 ? 294 ASN A CA 1 ATOM 2287 C C . ASN A 1 298 ? -5.741 -29.896 -28.917 1.00 76.46 ? 294 ASN A C 1 ATOM 2288 O O . ASN A 1 298 ? -6.441 -29.654 -27.933 1.00 80.36 ? 294 ASN A O 1 ATOM 2289 C CB . ASN A 1 298 ? -4.504 -28.543 -30.656 1.00 68.69 ? 294 ASN A CB 1 ATOM 2290 C CG . ASN A 1 298 ? -3.687 -27.912 -29.544 1.00 64.55 ? 294 ASN A CG 1 ATOM 2291 O OD1 . ASN A 1 298 ? -4.220 -27.475 -28.525 1.00 75.12 ? 294 ASN A OD1 1 ATOM 2292 N ND2 . ASN A 1 298 ? -2.375 -27.841 -29.751 1.00 62.47 ? 294 ASN A ND2 1 ATOM 2293 N N . SER A 1 299 ? -4.856 -30.885 -28.947 1.00 66.92 ? 295 SER A N 1 ATOM 2294 C CA . SER A 1 299 ? -4.688 -31.795 -27.820 1.00 70.47 ? 295 SER A CA 1 ATOM 2295 C C . SER A 1 299 ? -4.286 -31.062 -26.541 1.00 75.33 ? 295 SER A C 1 ATOM 2296 O O . SER A 1 299 ? -4.638 -31.489 -25.441 1.00 80.09 ? 295 SER A O 1 ATOM 2297 C CB . SER A 1 299 ? -3.641 -32.858 -28.157 1.00 77.53 ? 295 SER A CB 1 ATOM 2298 O OG . SER A 1 299 ? -2.368 -32.271 -28.355 1.00 84.21 ? 295 SER A OG 1 ATOM 2299 N N . VAL A 1 300 ? -3.555 -29.961 -26.689 1.00 78.93 ? 296 VAL A N 1 ATOM 2300 C CA . VAL A 1 300 ? -3.022 -29.236 -25.537 1.00 82.20 ? 296 VAL A CA 1 ATOM 2301 C C . VAL A 1 300 ? -4.012 -28.200 -24.996 1.00 78.31 ? 296 VAL A C 1 ATOM 2302 O O . VAL A 1 300 ? -3.859 -27.715 -23.874 1.00 83.40 ? 296 VAL A O 1 ATOM 2303 C CB . VAL A 1 300 ? -1.696 -28.515 -25.885 1.00 81.36 ? 296 VAL A CB 1 ATOM 2304 C CG1 . VAL A 1 300 ? -0.874 -28.283 -24.622 1.00 79.60 ? 296 VAL A CG1 1 ATOM 2305 C CG2 . VAL A 1 300 ? -0.886 -29.321 -26.899 1.00 71.30 ? 296 VAL A CG2 1 ATOM 2306 N N . GLY A 1 301 ? -5.034 -27.876 -25.783 1.00 71.65 ? 297 GLY A N 1 ATOM 2307 C CA . GLY A 1 301 ? -6.011 -26.878 -25.382 1.00 78.44 ? 297 GLY A CA 1 ATOM 2308 C C . GLY A 1 301 ? -6.739 -26.267 -26.563 1.00 75.80 ? 297 GLY A C 1 ATOM 2309 O O . GLY A 1 301 ? -6.790 -26.852 -27.643 1.00 75.71 ? 297 GLY A O 1 ATOM 2310 N N . GLY A 1 302 ? -7.308 -25.084 -26.356 1.00 68.19 ? 298 GLY A N 1 ATOM 2311 C CA . GLY A 1 302 ? -8.031 -24.398 -27.410 1.00 70.36 ? 298 GLY A CA 1 ATOM 2312 C C . GLY A 1 302 ? -8.212 -22.919 -27.131 1.00 83.10 ? 298 GLY A C 1 ATOM 2313 O O . GLY A 1 302 ? -8.179 -22.483 -25.980 1.00 92.42 ? 298 GLY A O 1 ATOM 2314 N N . GLU A 1 303 ? -8.405 -22.149 -28.198 1.00 76.62 ? 299 GLU A N 1 ATOM 2315 C CA . GLU A 1 303 ? -8.644 -20.714 -28.094 1.00 72.70 ? 299 GLU A CA 1 ATOM 2316 C C . GLU A 1 303 ? -9.627 -20.286 -29.179 1.00 72.16 ? 299 GLU A C 1 ATOM 2317 O O . GLU A 1 303 ? -9.868 -21.033 -30.129 1.00 69.69 ? 299 GLU A O 1 ATOM 2318 C CB . GLU A 1 303 ? -7.334 -19.931 -28.215 1.00 75.33 ? 299 GLU A CB 1 ATOM 2319 C CG . GLU A 1 303 ? -6.313 -20.227 -27.121 1.00 80.88 ? 299 GLU A CG 1 ATOM 2320 C CD . GLU A 1 303 ? -6.757 -19.751 -25.749 1.00 93.88 ? 299 GLU A CD 1 ATOM 2321 O OE1 . GLU A 1 303 ? -7.819 -19.102 -25.651 1.00 103.86 ? 299 GLU A OE1 1 ATOM 2322 O OE2 . GLU A 1 303 ? -6.037 -20.025 -24.765 1.00 95.84 ? 299 GLU A OE2 1 ATOM 2323 N N . SER A 1 304 ? -10.194 -19.090 -29.037 1.00 77.68 ? 300 SER A N 1 ATOM 2324 C CA . SER A 1 304 ? -11.206 -18.608 -29.974 1.00 68.57 ? 300 SER A CA 1 ATOM 2325 C C . SER A 1 304 ? -11.047 -17.121 -30.277 1.00 62.20 ? 300 SER A C 1 ATOM 2326 O O . SER A 1 304 ? -10.478 -16.373 -29.480 1.00 63.28 ? 300 SER A O 1 ATOM 2327 C CB . SER A 1 304 ? -12.605 -18.878 -29.419 1.00 60.06 ? 300 SER A CB 1 ATOM 2328 O OG . SER A 1 304 ? -12.874 -18.063 -28.293 1.00 79.52 ? 300 SER A OG 1 ATOM 2329 N N . VAL A 1 305 ? -11.559 -16.703 -31.434 1.00 56.60 ? 301 VAL A N 1 ATOM 2330 C CA . VAL A 1 305 ? -11.417 -15.323 -31.898 1.00 56.43 ? 301 VAL A CA 1 ATOM 2331 C C . VAL A 1 305 ? -12.695 -14.813 -32.561 1.00 57.62 ? 301 VAL A C 1 ATOM 2332 O O . VAL A 1 305 ? -13.235 -15.449 -33.467 1.00 56.81 ? 301 VAL A O 1 ATOM 2333 C CB . VAL A 1 305 ? -10.238 -15.194 -32.889 1.00 54.07 ? 301 VAL A CB 1 ATOM 2334 C CG1 . VAL A 1 305 ? -10.254 -13.841 -33.605 1.00 52.43 ? 301 VAL A CG1 1 ATOM 2335 C CG2 . VAL A 1 305 ? -8.921 -15.398 -32.156 1.00 67.91 ? 301 VAL A CG2 1 ATOM 2336 N N . GLU A 1 306 ? -13.166 -13.657 -32.102 1.00 61.97 ? 302 GLU A N 1 ATOM 2337 C CA . GLU A 1 306 ? -14.347 -13.013 -32.672 1.00 52.15 ? 302 GLU A CA 1 ATOM 2338 C C . GLU A 1 306 ? -14.018 -12.179 -33.909 1.00 53.57 ? 302 GLU A C 1 ATOM 2339 O O . GLU A 1 306 ? -12.921 -11.634 -34.026 1.00 60.93 ? 302 GLU A O 1 ATOM 2340 C CB . GLU A 1 306 ? -15.028 -12.128 -31.630 1.00 56.78 ? 302 GLU A CB 1 ATOM 2341 C CG . GLU A 1 306 ? -15.997 -12.870 -30.734 1.00 65.92 ? 302 GLU A CG 1 ATOM 2342 C CD . GLU A 1 306 ? -16.744 -11.944 -29.794 1.00 81.66 ? 302 GLU A CD 1 ATOM 2343 O OE1 . GLU A 1 306 ? -16.348 -10.765 -29.680 1.00 87.50 ? 302 GLU A OE1 1 ATOM 2344 O OE2 . GLU A 1 306 ? -17.730 -12.395 -29.175 1.00 83.32 ? 302 GLU A OE2 1 ATOM 2345 N N . THR A 1 307 ? -14.972 -12.096 -34.832 1.00 55.96 ? 303 THR A N 1 ATOM 2346 C CA . THR A 1 307 ? -14.841 -11.232 -36.004 1.00 58.37 ? 303 THR A CA 1 ATOM 2347 C C . THR A 1 307 ? -16.183 -10.582 -36.342 1.00 49.66 ? 303 THR A C 1 ATOM 2348 O O . THR A 1 307 ? -17.212 -11.257 -36.398 1.00 52.82 ? 303 THR A O 1 ATOM 2349 C CB . THR A 1 307 ? -14.321 -12.011 -37.231 1.00 54.36 ? 303 THR A CB 1 ATOM 2350 O OG1 . THR A 1 307 ? -13.065 -12.626 -36.916 1.00 65.66 ? 303 THR A OG1 1 ATOM 2351 C CG2 . THR A 1 307 ? -14.143 -11.081 -38.431 1.00 41.36 ? 303 THR A CG2 1 ATOM 2352 N N . VAL A 1 308 ? -16.159 -9.271 -36.571 1.00 51.14 ? 304 VAL A N 1 ATOM 2353 C CA . VAL A 1 308 ? -17.370 -8.512 -36.882 1.00 41.89 ? 304 VAL A CA 1 ATOM 2354 C C . VAL A 1 308 ? -17.413 -8.147 -38.362 1.00 41.63 ? 304 VAL A C 1 ATOM 2355 O O . VAL A 1 308 ? -16.614 -7.342 -38.840 1.00 50.87 ? 304 VAL A O 1 ATOM 2356 C CB . VAL A 1 308 ? -17.464 -7.224 -36.040 1.00 30.65 ? 304 VAL A CB 1 ATOM 2357 C CG1 . VAL A 1 308 ? -18.756 -6.470 -36.356 1.00 36.32 ? 304 VAL A CG1 1 ATOM 2358 C CG2 . VAL A 1 308 ? -17.386 -7.560 -34.557 1.00 40.97 ? 304 VAL A CG2 1 ATOM 2359 N N . LEU A 1 309 ? -18.364 -8.737 -39.078 1.00 37.61 ? 305 LEU A N 1 ATOM 2360 C CA . LEU A 1 309 ? -18.501 -8.511 -40.510 1.00 42.40 ? 305 LEU A CA 1 ATOM 2361 C C . LEU A 1 309 ? -19.695 -7.616 -40.812 1.00 61.19 ? 305 LEU A C 1 ATOM 2362 O O . LEU A 1 309 ? -20.745 -7.727 -40.180 1.00 68.99 ? 305 LEU A O 1 ATOM 2363 C CB . LEU A 1 309 ? -18.651 -9.840 -41.249 1.00 56.93 ? 305 LEU A CB 1 ATOM 2364 C CG . LEU A 1 309 ? -18.762 -9.739 -42.772 1.00 57.36 ? 305 LEU A CG 1 ATOM 2365 C CD1 . LEU A 1 309 ? -17.429 -9.321 -43.391 1.00 58.19 ? 305 LEU A CD1 1 ATOM 2366 C CD2 . LEU A 1 309 ? -19.248 -11.058 -43.343 1.00 44.61 ? 305 LEU A CD2 1 ATOM 2367 N N . THR A 1 310 ? -19.516 -6.726 -41.783 1.00 56.98 ? 306 THR A N 1 ATOM 2368 C CA . THR A 1 310 ? -20.601 -5.892 -42.279 1.00 42.41 ? 306 THR A CA 1 ATOM 2369 C C . THR A 1 310 ? -20.548 -5.855 -43.801 1.00 41.36 ? 306 THR A C 1 ATOM 2370 O O . THR A 1 310 ? -19.557 -5.416 -44.385 1.00 42.38 ? 306 THR A O 1 ATOM 2371 C CB . THR A 1 310 ? -20.524 -4.461 -41.714 1.00 44.61 ? 306 THR A CB 1 ATOM 2372 O OG1 . THR A 1 310 ? -20.511 -4.515 -40.281 1.00 44.39 ? 306 THR A OG1 1 ATOM 2373 C CG2 . THR A 1 310 ? -21.717 -3.629 -42.179 1.00 48.73 ? 306 THR A CG2 1 ATOM 2374 N N . VAL A 1 311 ? -21.614 -6.326 -44.438 1.00 50.92 ? 307 VAL A N 1 ATOM 2375 C CA . VAL A 1 311 ? -21.695 -6.325 -45.893 1.00 54.74 ? 307 VAL A CA 1 ATOM 2376 C C . VAL A 1 311 ? -22.468 -5.098 -46.357 1.00 49.57 ? 307 VAL A C 1 ATOM 2377 O O . VAL A 1 311 ? -23.588 -4.845 -45.909 1.00 45.60 ? 307 VAL A O 1 ATOM 2378 C CB . VAL A 1 311 ? -22.358 -7.606 -46.434 1.00 39.22 ? 307 VAL A CB 1 ATOM 2379 C CG1 . VAL A 1 311 ? -22.460 -7.556 -47.963 1.00 36.98 ? 307 VAL A CG1 1 ATOM 2380 C CG2 . VAL A 1 311 ? -21.568 -8.831 -45.987 1.00 38.32 ? 307 VAL A CG2 1 ATOM 2381 N N . THR A 1 312 ? -21.852 -4.342 -47.258 1.00 42.11 ? 308 THR A N 1 ATOM 2382 C CA . THR A 1 312 ? -22.421 -3.094 -47.740 1.00 34.90 ? 308 THR A CA 1 ATOM 2383 C C . THR A 1 312 ? -23.018 -3.272 -49.127 1.00 56.75 ? 308 THR A C 1 ATOM 2384 O O . THR A 1 312 ? -22.486 -4.017 -49.951 1.00 51.88 ? 308 THR A O 1 ATOM 2385 C CB . THR A 1 312 ? -21.364 -1.977 -47.782 1.00 47.62 ? 308 THR A CB 1 ATOM 2386 O OG1 . THR A 1 312 ? -20.340 -2.311 -48.728 1.00 33.67 ? 308 THR A OG1 1 ATOM 2387 C CG2 . THR A 1 312 ? -20.745 -1.781 -46.407 1.00 27.60 ? 308 THR A CG2 1 ATOM 2388 N N . ALA A 1 313 ? -24.129 -2.586 -49.368 1.00 58.20 ? 309 ALA A N 1 ATOM 2389 C CA . ALA A 1 313 ? -24.799 -2.614 -50.661 1.00 53.71 ? 309 ALA A CA 1 ATOM 2390 C C . ALA A 1 313 ? -24.927 -1.191 -51.205 1.00 52.13 ? 309 ALA A C 1 ATOM 2391 O O . ALA A 1 313 ? -25.011 -0.238 -50.430 1.00 52.44 ? 309 ALA A O 1 ATOM 2392 C CB . ALA A 1 313 ? -26.166 -3.275 -50.535 1.00 49.69 ? 309 ALA A CB 1 ATOM 2393 N N . PRO A 1 314 ? -24.933 -1.043 -52.539 1.00 44.17 ? 310 PRO A N 1 ATOM 2394 C CA . PRO A 1 314 ? -24.988 0.289 -53.157 1.00 41.53 ? 310 PRO A CA 1 ATOM 2395 C C . PRO A 1 314 ? -26.255 1.060 -52.792 1.00 50.76 ? 310 PRO A C 1 ATOM 2396 O O . PRO A 1 314 ? -27.357 0.516 -52.877 1.00 49.68 ? 310 PRO A O 1 ATOM 2397 C CB . PRO A 1 314 ? -24.943 -0.019 -54.658 1.00 42.01 ? 310 PRO A CB 1 ATOM 2398 C CG . PRO A 1 314 ? -25.430 -1.431 -54.777 1.00 51.49 ? 310 PRO A CG 1 ATOM 2399 C CD . PRO A 1 314 ? -24.941 -2.119 -53.545 1.00 37.56 ? 310 PRO A CD 1 ATOM 2400 N N . LEU A 1 315 ? -26.086 2.315 -52.384 1.00 43.82 ? 311 LEU A N 1 ATOM 2401 C CA . LEU A 1 315 ? -27.210 3.163 -52.007 1.00 46.99 ? 311 LEU A CA 1 ATOM 2402 C C . LEU A 1 315 ? -27.957 3.662 -53.236 1.00 37.20 ? 311 LEU A C 1 ATOM 2403 O O . LEU A 1 315 ? -27.366 4.246 -54.145 1.00 39.08 ? 311 LEU A O 1 ATOM 2404 C CB . LEU A 1 315 ? -26.732 4.355 -51.175 1.00 35.71 ? 311 LEU A CB 1 ATOM 2405 C CG . LEU A 1 315 ? -26.101 4.035 -49.821 1.00 26.00 ? 311 LEU A CG 1 ATOM 2406 C CD1 . LEU A 1 315 ? -25.573 5.315 -49.195 1.00 41.61 ? 311 LEU A CD1 1 ATOM 2407 C CD2 . LEU A 1 315 ? -27.098 3.341 -48.894 1.00 26.48 ? 311 LEU A CD2 1 ATOM 2408 N N . SER A 1 316 ? -29.262 3.420 -53.253 1.00 43.01 ? 312 SER A N 1 ATOM 2409 C CA . SER A 1 316 ? -30.128 3.916 -54.313 1.00 52.42 ? 312 SER A CA 1 ATOM 2410 C C . SER A 1 316 ? -31.434 4.375 -53.689 1.00 46.54 ? 312 SER A C 1 ATOM 2411 O O . SER A 1 316 ? -31.851 3.851 -52.655 1.00 47.17 ? 312 SER A O 1 ATOM 2412 C CB . SER A 1 316 ? -30.380 2.839 -55.370 1.00 52.65 ? 312 SER A CB 1 ATOM 2413 O OG . SER A 1 316 ? -31.041 1.717 -54.812 1.00 62.05 ? 312 SER A OG 1 ATOM 2414 N N . ALA A 1 317 ? -32.073 5.359 -54.311 1.00 48.57 ? 313 ALA A N 1 ATOM 2415 C CA . ALA A 1 317 ? -33.300 5.923 -53.769 1.00 50.22 ? 313 ALA A CA 1 ATOM 2416 C C . ALA A 1 317 ? -34.249 6.341 -54.881 1.00 45.54 ? 313 ALA A C 1 ATOM 2417 O O . ALA A 1 317 ? -33.821 6.794 -55.944 1.00 38.56 ? 313 ALA A O 1 ATOM 2418 C CB . ALA A 1 317 ? -32.985 7.108 -52.866 1.00 53.51 ? 313 ALA A CB 1 ATOM 2419 N N . LYS A 1 318 ? -35.541 6.165 -54.629 1.00 49.85 ? 314 LYS A N 1 ATOM 2420 C CA . LYS A 1 318 ? -36.572 6.580 -55.568 1.00 53.36 ? 314 LYS A CA 1 ATOM 2421 C C . LYS A 1 318 ? -37.749 7.184 -54.812 1.00 58.95 ? 314 LYS A C 1 ATOM 2422 O O . LYS A 1 318 ? -38.282 6.571 -53.885 1.00 58.56 ? 314 LYS A O 1 ATOM 2423 C CB . LYS A 1 318 ? -37.029 5.396 -56.426 1.00 45.14 ? 314 LYS A CB 1 ATOM 2424 C CG . LYS A 1 318 ? -38.070 5.748 -57.481 1.00 67.68 ? 314 LYS A CG 1 ATOM 2425 C CD . LYS A 1 318 ? -37.678 6.987 -58.274 1.00 83.30 ? 314 LYS A CD 1 ATOM 2426 C CE . LYS A 1 318 ? -38.573 7.180 -59.484 1.00 80.09 ? 314 LYS A CE 1 ATOM 2427 N NZ . LYS A 1 318 ? -38.245 6.224 -60.577 1.00 96.54 ? 314 LYS A NZ 1 ATOM 2428 N N . ILE A 1 319 ? -38.146 8.388 -55.211 1.00 58.25 ? 315 ILE A N 1 ATOM 2429 C CA . ILE A 1 319 ? -39.248 9.091 -54.562 1.00 48.24 ? 315 ILE A CA 1 ATOM 2430 C C . ILE A 1 319 ? -40.581 8.698 -55.184 1.00 50.38 ? 315 ILE A C 1 ATOM 2431 O O . ILE A 1 319 ? -40.714 8.635 -56.408 1.00 50.37 ? 315 ILE A O 1 ATOM 2432 C CB . ILE A 1 319 ? -39.075 10.624 -54.650 1.00 54.10 ? 315 ILE A CB 1 ATOM 2433 C CG1 . ILE A 1 319 ? -37.926 11.075 -53.745 1.00 60.83 ? 315 ILE A CG1 1 ATOM 2434 C CG2 . ILE A 1 319 ? -40.368 11.343 -54.246 1.00 61.99 ? 315 ILE A CG2 1 ATOM 2435 C CD1 . ILE A 1 319 ? -37.465 12.498 -53.996 1.00 58.67 ? 315 ILE A CD1 1 ATOM 2436 N N . ASP A 1 320 ? -41.559 8.432 -54.324 1.00 50.13 ? 316 ASP A N 1 ATOM 2437 C CA . ASP A 1 320 ? -42.916 8.101 -54.745 1.00 49.61 ? 316 ASP A CA 1 ATOM 2438 C C . ASP A 1 320 ? -43.916 9.164 -54.271 1.00 54.00 ? 316 ASP A C 1 ATOM 2439 O O . ASP A 1 320 ? -44.074 9.360 -53.065 1.00 47.92 ? 316 ASP A O 1 ATOM 2440 C CB . ASP A 1 320 ? -43.318 6.728 -54.200 1.00 50.04 ? 316 ASP A CB 1 ATOM 2441 C CG . ASP A 1 320 ? -44.798 6.446 -54.363 1.00 61.52 ? 316 ASP A CG 1 ATOM 2442 O OD1 . ASP A 1 320 ? -45.202 6.005 -55.460 1.00 63.93 ? 316 ASP A OD1 1 ATOM 2443 O OD2 . ASP A 1 320 ? -45.555 6.660 -53.393 1.00 66.46 ? 316 ASP A OD2 1 ATOM 2444 N N . PRO A 1 321 ? -44.596 9.860 -55.204 1.00 43.81 ? 317 PRO A N 1 ATOM 2445 C CA . PRO A 1 321 ? -44.469 9.881 -56.668 1.00 45.10 ? 317 PRO A CA 1 ATOM 2446 C C . PRO A 1 321 ? -43.328 10.780 -57.153 1.00 49.90 ? 317 PRO A C 1 ATOM 2447 O O . PRO A 1 321 ? -42.922 11.673 -56.410 1.00 46.47 ? 317 PRO A O 1 ATOM 2448 C CB . PRO A 1 321 ? -45.820 10.429 -57.118 1.00 49.26 ? 317 PRO A CB 1 ATOM 2449 C CG . PRO A 1 321 ? -46.198 11.377 -56.031 1.00 57.26 ? 317 PRO A CG 1 ATOM 2450 C CD . PRO A 1 321 ? -45.674 10.760 -54.749 1.00 45.90 ? 317 PRO A CD 1 ATOM 2451 N N . PRO A 1 322 ? -42.827 10.561 -58.384 1.00 58.16 ? 318 PRO A N 1 ATOM 2452 C CA . PRO A 1 322 ? -41.820 11.462 -58.966 1.00 63.60 ? 318 PRO A CA 1 ATOM 2453 C C . PRO A 1 322 ? -42.349 12.888 -59.113 1.00 61.58 ? 318 PRO A C 1 ATOM 2454 O O . PRO A 1 322 ? -41.579 13.848 -59.054 1.00 56.36 ? 318 PRO A O 1 ATOM 2455 C CB . PRO A 1 322 ? -41.535 10.840 -60.340 1.00 67.99 ? 318 PRO A CB 1 ATOM 2456 C CG . PRO A 1 322 ? -42.007 9.423 -60.236 1.00 62.08 ? 318 PRO A CG 1 ATOM 2457 C CD . PRO A 1 322 ? -43.176 9.467 -59.306 1.00 64.06 ? 318 PRO A CD 1 ATOM 2458 N N . THR A 1 323 ? -43.658 13.009 -59.310 1.00 65.12 ? 319 THR A N 1 ATOM 2459 C CA . THR A 1 323 ? -44.312 14.307 -59.413 1.00 53.46 ? 319 THR A CA 1 ATOM 2460 C C . THR A 1 323 ? -45.758 14.197 -58.950 1.00 49.68 ? 319 THR A C 1 ATOM 2461 O O . THR A 1 323 ? -46.392 13.156 -59.123 1.00 51.91 ? 319 THR A O 1 ATOM 2462 C CB . THR A 1 323 ? -44.282 14.851 -60.854 1.00 53.30 ? 319 THR A CB 1 ATOM 2463 O OG1 . THR A 1 323 ? -44.879 16.154 -60.886 1.00 59.19 ? 319 THR A OG1 1 ATOM 2464 C CG2 . THR A 1 323 ? -45.033 13.917 -61.810 1.00 58.54 ? 319 THR A CG2 1 ATOM 2465 N N . GLN A 1 324 ? -46.277 15.266 -58.356 1.00 45.70 ? 320 GLN A N 1 ATOM 2466 C CA . GLN A 1 324 ? -47.684 15.306 -57.985 1.00 49.75 ? 320 GLN A CA 1 ATOM 2467 C C . GLN A 1 324 ? -48.230 16.728 -57.995 1.00 44.11 ? 320 GLN A C 1 ATOM 2468 O O . GLN A 1 324 ? -47.534 17.678 -57.634 1.00 47.81 ? 320 GLN A O 1 ATOM 2469 C CB . GLN A 1 324 ? -47.893 14.675 -56.608 1.00 51.54 ? 320 GLN A CB 1 ATOM 2470 C CG . GLN A 1 324 ? -47.034 15.267 -55.502 1.00 44.01 ? 320 GLN A CG 1 ATOM 2471 C CD . GLN A 1 324 ? -47.443 14.774 -54.123 1.00 46.54 ? 320 GLN A CD 1 ATOM 2472 O OE1 . GLN A 1 324 ? -48.628 14.596 -53.841 1.00 61.39 ? 320 GLN A OE1 1 ATOM 2473 N NE2 . GLN A 1 324 ? -46.461 14.547 -53.259 1.00 38.74 ? 320 GLN A NE2 1 ATOM 2474 N N . THR A 1 325 ? -49.486 16.857 -58.409 1.00 57.36 ? 321 THR A N 1 ATOM 2475 C CA . THR A 1 325 ? -50.174 18.140 -58.424 1.00 58.19 ? 321 THR A CA 1 ATOM 2476 C C . THR A 1 325 ? -51.169 18.194 -57.274 1.00 57.86 ? 321 THR A C 1 ATOM 2477 O O . THR A 1 325 ? -51.884 17.225 -57.015 1.00 67.65 ? 321 THR A O 1 ATOM 2478 C CB . THR A 1 325 ? -50.908 18.377 -59.754 1.00 57.45 ? 321 THR A CB 1 ATOM 2479 O OG1 . THR A 1 325 ? -49.991 18.210 -60.842 1.00 59.30 ? 321 THR A OG1 1 ATOM 2480 C CG2 . THR A 1 325 ? -51.506 19.781 -59.797 1.00 51.56 ? 321 THR A CG2 1 ATOM 2481 N N . VAL A 1 326 ? -51.207 19.330 -56.586 1.00 53.90 ? 322 VAL A N 1 ATOM 2482 C CA . VAL A 1 326 ? -52.096 19.512 -55.447 1.00 52.43 ? 322 VAL A CA 1 ATOM 2483 C C . VAL A 1 326 ? -52.649 20.933 -55.472 1.00 59.53 ? 322 VAL A C 1 ATOM 2484 O O . VAL A 1 326 ? -52.082 21.816 -56.114 1.00 66.03 ? 322 VAL A O 1 ATOM 2485 C CB . VAL A 1 326 ? -51.365 19.239 -54.106 1.00 52.18 ? 322 VAL A CB 1 ATOM 2486 C CG1 . VAL A 1 326 ? -52.336 19.282 -52.926 1.00 52.68 ? 322 VAL A CG1 1 ATOM 2487 C CG2 . VAL A 1 326 ? -50.655 17.890 -54.153 1.00 44.21 ? 322 VAL A CG2 1 ATOM 2488 N N . ASP A 1 327 ? -53.758 21.144 -54.772 1.00 68.52 ? 323 ASP A N 1 ATOM 2489 C CA . ASP A 1 327 ? -54.404 22.447 -54.714 1.00 71.27 ? 323 ASP A CA 1 ATOM 2490 C C . ASP A 1 327 ? -54.176 23.080 -53.348 1.00 59.97 ? 323 ASP A C 1 ATOM 2491 O O . ASP A 1 327 ? -54.002 22.382 -52.348 1.00 52.03 ? 323 ASP A O 1 ATOM 2492 C CB . ASP A 1 327 ? -55.900 22.320 -55.009 1.00 78.24 ? 323 ASP A CB 1 ATOM 2493 C CG . ASP A 1 327 ? -56.176 21.911 -56.445 1.00 81.79 ? 323 ASP A CG 1 ATOM 2494 O OD1 . ASP A 1 327 ? -56.274 20.695 -56.711 1.00 74.28 ? 323 ASP A OD1 1 ATOM 2495 O OD2 . ASP A 1 327 ? -56.290 22.807 -57.309 1.00 84.04 ? 323 ASP A OD2 1 ATOM 2496 N N . PHE A 1 328 ? -54.161 24.408 -53.329 1.00 48.01 ? 324 PHE A N 1 ATOM 2497 C CA . PHE A 1 328 ? -53.847 25.175 -52.131 1.00 58.85 ? 324 PHE A CA 1 ATOM 2498 C C . PHE A 1 328 ? -54.734 24.753 -50.958 1.00 48.16 ? 324 PHE A C 1 ATOM 2499 O O . PHE A 1 328 ? -55.961 24.763 -51.062 1.00 65.21 ? 324 PHE A O 1 ATOM 2500 C CB . PHE A 1 328 ? -54.020 26.668 -52.443 1.00 69.18 ? 324 PHE A CB 1 ATOM 2501 C CG . PHE A 1 328 ? -53.601 27.598 -51.334 1.00 81.58 ? 324 PHE A CG 1 ATOM 2502 C CD1 . PHE A 1 328 ? -52.859 27.157 -50.254 1.00 73.96 ? 324 PHE A CD1 1 ATOM 2503 C CD2 . PHE A 1 328 ? -53.958 28.934 -51.384 1.00 81.86 ? 324 PHE A CD2 1 ATOM 2504 C CE1 . PHE A 1 328 ? -52.489 28.032 -49.250 1.00 63.23 ? 324 PHE A CE1 1 ATOM 2505 C CE2 . PHE A 1 328 ? -53.591 29.802 -50.384 1.00 75.14 ? 324 PHE A CE2 1 ATOM 2506 C CZ . PHE A 1 328 ? -52.854 29.350 -49.318 1.00 59.34 ? 324 PHE A CZ 1 ATOM 2507 N N . GLY A 1 329 ? -54.099 24.377 -49.849 1.00 45.51 ? 325 GLY A N 1 ATOM 2508 C CA . GLY A 1 329 ? -54.802 23.981 -48.640 1.00 54.78 ? 325 GLY A CA 1 ATOM 2509 C C . GLY A 1 329 ? -54.809 22.481 -48.389 1.00 60.35 ? 325 GLY A C 1 ATOM 2510 O O . GLY A 1 329 ? -55.034 22.040 -47.261 1.00 62.20 ? 325 GLY A O 1 ATOM 2511 N N . ARG A 1 330 ? -54.556 21.697 -49.433 1.00 55.44 ? 326 ARG A N 1 ATOM 2512 C CA . ARG A 1 330 ? -54.557 20.236 -49.321 1.00 59.56 ? 326 ARG A CA 1 ATOM 2513 C C . ARG A 1 330 ? -53.169 19.698 -48.957 1.00 64.33 ? 326 ARG A C 1 ATOM 2514 O O . ARG A 1 330 ? -52.169 20.188 -49.473 1.00 65.05 ? 326 ARG A O 1 ATOM 2515 C CB . ARG A 1 330 ? -55.028 19.601 -50.630 1.00 62.74 ? 326 ARG A CB 1 ATOM 2516 C CG . ARG A 1 330 ? -56.516 19.743 -50.878 1.00 56.33 ? 326 ARG A CG 1 ATOM 2517 C CD . ARG A 1 330 ? -57.291 18.583 -50.282 1.00 64.76 ? 326 ARG A CD 1 ATOM 2518 N NE . ARG A 1 330 ? -58.723 18.702 -50.538 1.00 67.49 ? 326 ARG A NE 1 ATOM 2519 C CZ . ARG A 1 330 ? -59.303 18.411 -51.698 1.00 57.57 ? 326 ARG A CZ 1 ATOM 2520 N NH1 . ARG A 1 330 ? -60.612 18.553 -51.838 1.00 58.68 ? 326 ARG A NH1 1 ATOM 2521 N NH2 . ARG A 1 330 ? -58.577 17.983 -52.722 1.00 51.55 ? 326 ARG A NH2 1 ATOM 2522 N N . PRO A 1 331 ? -53.100 18.689 -48.067 1.00 64.57 ? 327 PRO A N 1 ATOM 2523 C CA . PRO A 1 331 ? -51.800 18.079 -47.749 1.00 64.22 ? 327 PRO A CA 1 ATOM 2524 C C . PRO A 1 331 ? -51.096 17.458 -48.953 1.00 59.78 ? 327 PRO A C 1 ATOM 2525 O O . PRO A 1 331 ? -51.744 16.888 -49.833 1.00 60.07 ? 327 PRO A O 1 ATOM 2526 C CB . PRO A 1 331 ? -52.158 16.997 -46.723 1.00 65.60 ? 327 PRO A CB 1 ATOM 2527 C CG . PRO A 1 331 ? -53.429 17.449 -46.109 1.00 70.54 ? 327 PRO A CG 1 ATOM 2528 C CD . PRO A 1 331 ? -54.170 18.194 -47.181 1.00 64.93 ? 327 PRO A CD 1 ATOM 2529 N N . ALA A 1 332 ? -49.772 17.582 -48.975 1.00 61.56 ? 328 ALA A N 1 ATOM 2530 C CA . ALA A 1 332 ? -48.940 16.961 -49.996 1.00 59.60 ? 328 ALA A CA 1 ATOM 2531 C C . ALA A 1 332 ? -47.799 16.217 -49.314 1.00 48.23 ? 328 ALA A C 1 ATOM 2532 O O . ALA A 1 332 ? -46.980 16.824 -48.623 1.00 52.91 ? 328 ALA A O 1 ATOM 2533 C CB . ALA A 1 332 ? -48.403 18.003 -50.970 1.00 55.52 ? 328 ALA A CB 1 ATOM 2534 N N . VAL A 1 333 ? -47.761 14.901 -49.504 1.00 52.78 ? 329 VAL A N 1 ATOM 2535 C CA . VAL A 1 333 ? -46.770 14.052 -48.850 1.00 40.09 ? 329 VAL A CA 1 ATOM 2536 C C . VAL A 1 333 ? -45.796 13.464 -49.865 1.00 40.48 ? 329 VAL A C 1 ATOM 2537 O O . VAL A 1 333 ? -46.182 13.091 -50.974 1.00 36.58 ? 329 VAL A O 1 ATOM 2538 C CB . VAL A 1 333 ? -47.446 12.907 -48.059 1.00 37.69 ? 329 VAL A CB 1 ATOM 2539 C CG1 . VAL A 1 333 ? -46.404 11.948 -47.470 1.00 42.18 ? 329 VAL A CG1 1 ATOM 2540 C CG2 . VAL A 1 333 ? -48.327 13.485 -46.957 1.00 57.17 ? 329 VAL A CG2 1 ATOM 2541 N N . PHE A 1 334 ? -44.529 13.402 -49.466 1.00 55.43 ? 330 PHE A N 1 ATOM 2542 C CA . PHE A 1 334 ? -43.484 12.752 -50.246 1.00 40.09 ? 330 PHE A CA 1 ATOM 2543 C C . PHE A 1 334 ? -42.860 11.632 -49.424 1.00 39.58 ? 330 PHE A C 1 ATOM 2544 O O . PHE A 1 334 ? -42.573 11.809 -48.239 1.00 41.07 ? 330 PHE A O 1 ATOM 2545 C CB . PHE A 1 334 ? -42.412 13.755 -50.671 1.00 44.53 ? 330 PHE A CB 1 ATOM 2546 C CG . PHE A 1 334 ? -42.842 14.663 -51.789 1.00 43.33 ? 330 PHE A CG 1 ATOM 2547 C CD1 . PHE A 1 334 ? -42.732 14.256 -53.107 1.00 45.31 ? 330 PHE A CD1 1 ATOM 2548 C CD2 . PHE A 1 334 ? -43.353 15.920 -51.524 1.00 27.85 ? 330 PHE A CD2 1 ATOM 2549 C CE1 . PHE A 1 334 ? -43.126 15.086 -54.138 1.00 44.47 ? 330 PHE A CE1 1 ATOM 2550 C CE2 . PHE A 1 334 ? -43.747 16.752 -52.553 1.00 30.10 ? 330 PHE A CE2 1 ATOM 2551 C CZ . PHE A 1 334 ? -43.634 16.333 -53.861 1.00 32.60 ? 330 PHE A CZ 1 ATOM 2552 N N . THR A 1 335 ? -42.658 10.482 -50.060 1.00 54.98 ? 331 THR A N 1 ATOM 2553 C CA . THR A 1 335 ? -42.078 9.322 -49.392 1.00 54.47 ? 331 THR A CA 1 ATOM 2554 C C . THR A 1 335 ? -40.822 8.855 -50.123 1.00 46.25 ? 331 THR A C 1 ATOM 2555 O O . THR A 1 335 ? -40.869 8.519 -51.308 1.00 46.44 ? 331 THR A O 1 ATOM 2556 C CB . THR A 1 335 ? -43.087 8.162 -49.305 1.00 38.68 ? 331 THR A CB 1 ATOM 2557 O OG1 . THR A 1 335 ? -44.319 8.642 -48.751 1.00 49.13 ? 331 THR A OG1 1 ATOM 2558 C CG2 . THR A 1 335 ? -42.538 7.040 -48.432 1.00 42.62 ? 331 THR A CG2 1 ATOM 2559 N N . CYS A 1 336 ? -39.701 8.846 -49.407 1.00 42.79 ? 332 CYS A N 1 ATOM 2560 C CA . CYS A 1 336 ? -38.424 8.431 -49.977 1.00 52.90 ? 332 CYS A CA 1 ATOM 2561 C C . CYS A 1 336 ? -38.164 6.951 -49.694 1.00 54.97 ? 332 CYS A C 1 ATOM 2562 O O . CYS A 1 336 ? -38.082 6.531 -48.538 1.00 53.09 ? 332 CYS A O 1 ATOM 2563 C CB . CYS A 1 336 ? -37.285 9.293 -49.423 1.00 62.32 ? 332 CYS A CB 1 ATOM 2564 S SG . CYS A 1 336 ? -35.644 8.876 -50.056 1.00 52.14 ? 332 CYS A SG 1 ATOM 2565 N N . GLN A 1 337 ? -38.041 6.173 -50.766 1.00 50.09 ? 333 GLN A N 1 ATOM 2566 C CA . GLN A 1 337 ? -37.820 4.733 -50.679 1.00 44.89 ? 333 GLN A CA 1 ATOM 2567 C C . GLN A 1 337 ? -36.384 4.423 -51.071 1.00 47.59 ? 333 GLN A C 1 ATOM 2568 O O . GLN A 1 337 ? -35.910 4.901 -52.100 1.00 52.12 ? 333 GLN A O 1 ATOM 2569 C CB . GLN A 1 337 ? -38.797 3.993 -51.588 1.00 44.14 ? 333 GLN A CB 1 ATOM 2570 C CG . GLN A 1 337 ? -40.248 4.344 -51.322 1.00 40.29 ? 333 GLN A CG 1 ATOM 2571 C CD . GLN A 1 337 ? -41.186 3.790 -52.372 1.00 37.85 ? 333 GLN A CD 1 ATOM 2572 O OE1 . GLN A 1 337 ? -40.880 3.801 -53.565 1.00 36.00 ? 333 GLN A OE1 1 ATOM 2573 N NE2 . GLN A 1 337 ? -42.339 3.300 -51.934 1.00 36.51 ? 333 GLN A NE2 1 ATOM 2574 N N . TYR A 1 338 ? -35.697 3.621 -50.260 1.00 48.10 ? 334 TYR A N 1 ATOM 2575 C CA . TYR A 1 338 ? -34.264 3.415 -50.443 1.00 52.80 ? 334 TYR A CA 1 ATOM 2576 C C . TYR A 1 338 ? -33.813 1.969 -50.299 1.00 51.25 ? 334 TYR A C 1 ATOM 2577 O O . TYR A 1 338 ? -34.550 1.104 -49.821 1.00 64.06 ? 334 TYR A O 1 ATOM 2578 C CB . TYR A 1 338 ? -33.487 4.282 -49.449 1.00 48.65 ? 334 TYR A CB 1 ATOM 2579 C CG . TYR A 1 338 ? -33.922 4.117 -48.005 1.00 43.59 ? 334 TYR A CG 1 ATOM 2580 C CD1 . TYR A 1 338 ? -34.949 4.886 -47.475 1.00 40.30 ? 334 TYR A CD1 1 ATOM 2581 C CD2 . TYR A 1 338 ? -33.300 3.199 -47.170 1.00 40.37 ? 334 TYR A CD2 1 ATOM 2582 C CE1 . TYR A 1 338 ? -35.347 4.742 -46.156 1.00 42.82 ? 334 TYR A CE1 1 ATOM 2583 C CE2 . TYR A 1 338 ? -33.693 3.048 -45.849 1.00 39.77 ? 334 TYR A CE2 1 ATOM 2584 C CZ . TYR A 1 338 ? -34.715 3.822 -45.348 1.00 51.69 ? 334 TYR A CZ 1 ATOM 2585 O OH . TYR A 1 338 ? -35.110 3.677 -44.036 1.00 59.56 ? 334 TYR A OH 1 ATOM 2586 N N . THR A 1 339 ? -32.580 1.734 -50.735 1.00 45.68 ? 335 THR A N 1 ATOM 2587 C CA . THR A 1 339 ? -31.921 0.445 -50.609 1.00 48.07 ? 335 THR A CA 1 ATOM 2588 C C . THR A 1 339 ? -30.461 0.682 -50.245 1.00 51.74 ? 335 THR A C 1 ATOM 2589 O O . THR A 1 339 ? -30.059 1.812 -49.958 1.00 42.61 ? 335 THR A O 1 ATOM 2590 C CB . THR A 1 339 ? -32.001 -0.378 -51.909 1.00 45.09 ? 335 THR A CB 1 ATOM 2591 O OG1 . THR A 1 339 ? -31.273 0.288 -52.948 1.00 43.23 ? 335 THR A OG1 1 ATOM 2592 C CG2 . THR A 1 339 ? -33.448 -0.570 -52.342 1.00 58.81 ? 335 THR A CG2 1 ATOM 2593 N N . GLY A 1 340 ? -29.672 -0.386 -50.254 1.00 54.34 ? 336 GLY A N 1 ATOM 2594 C CA . GLY A 1 340 ? -28.267 -0.297 -49.913 1.00 41.38 ? 336 GLY A CA 1 ATOM 2595 C C . GLY A 1 340 ? -28.076 -0.447 -48.418 1.00 45.36 ? 336 GLY A C 1 ATOM 2596 O O . GLY A 1 340 ? -29.010 -0.228 -47.645 1.00 42.14 ? 336 GLY A O 1 ATOM 2597 N N . ASN A 1 341 ? -26.868 -0.827 -48.014 1.00 45.54 ? 337 ASN A N 1 ATOM 2598 C CA . ASN A 1 341 ? -26.546 -1.000 -46.603 1.00 46.55 ? 337 ASN A CA 1 ATOM 2599 C C . ASN A 1 341 ? -25.135 -0.484 -46.306 1.00 47.10 ? 337 ASN A C 1 ATOM 2600 O O . ASN A 1 341 ? -24.250 -0.599 -47.152 1.00 37.80 ? 337 ASN A O 1 ATOM 2601 C CB . ASN A 1 341 ? -26.668 -2.476 -46.211 1.00 37.91 ? 337 ASN A CB 1 ATOM 2602 C CG . ASN A 1 341 ? -26.949 -2.671 -44.733 1.00 39.51 ? 337 ASN A CG 1 ATOM 2603 O OD1 . ASN A 1 341 ? -28.012 -2.297 -44.239 1.00 49.21 ? 337 ASN A OD1 1 ATOM 2604 N ND2 . ASN A 1 341 ? -26.004 -3.274 -44.023 1.00 35.80 ? 337 ASN A ND2 1 ATOM 2605 N N . PRO A 1 342 ? -24.920 0.111 -45.117 1.00 42.15 ? 338 PRO A N 1 ATOM 2606 C CA . PRO A 1 342 ? -25.922 0.480 -44.111 1.00 53.78 ? 338 PRO A CA 1 ATOM 2607 C C . PRO A 1 342 ? -26.520 1.860 -44.358 1.00 45.65 ? 338 PRO A C 1 ATOM 2608 O O . PRO A 1 342 ? -26.129 2.545 -45.307 1.00 44.09 ? 338 PRO A O 1 ATOM 2609 C CB . PRO A 1 342 ? -25.126 0.460 -42.810 1.00 41.51 ? 338 PRO A CB 1 ATOM 2610 C CG . PRO A 1 342 ? -23.754 0.873 -43.221 1.00 43.28 ? 338 PRO A CG 1 ATOM 2611 C CD . PRO A 1 342 ? -23.549 0.323 -44.616 1.00 41.24 ? 338 PRO A CD 1 ATOM 2612 N N . ILE A 1 343 ? -27.458 2.251 -43.501 1.00 40.01 ? 339 ILE A N 1 ATOM 2613 C CA . ILE A 1 343 ? -28.074 3.572 -43.556 1.00 45.84 ? 339 ILE A CA 1 ATOM 2614 C C . ILE A 1 343 ? -27.865 4.277 -42.224 1.00 59.55 ? 339 ILE A C 1 ATOM 2615 O O . ILE A 1 343 ? -27.967 3.661 -41.161 1.00 81.17 ? 339 ILE A O 1 ATOM 2616 C CB . ILE A 1 343 ? -29.588 3.493 -43.868 1.00 35.09 ? 339 ILE A CB 1 ATOM 2617 C CG1 . ILE A 1 343 ? -29.825 2.776 -45.202 1.00 41.87 ? 339 ILE A CG1 1 ATOM 2618 C CG2 . ILE A 1 343 ? -30.215 4.891 -43.880 1.00 43.39 ? 339 ILE A CG2 1 ATOM 2619 C CD1 . ILE A 1 343 ? -29.269 3.506 -46.421 1.00 32.02 ? 339 ILE A CD1 1 ATOM 2620 N N . LYS A 1 344 ? -27.561 5.568 -42.294 1.00 47.35 ? 340 LYS A N 1 ATOM 2621 C CA . LYS A 1 344 ? -27.399 6.394 -41.106 1.00 51.46 ? 340 LYS A CA 1 ATOM 2622 C C . LYS A 1 344 ? -28.384 7.554 -41.151 1.00 61.36 ? 340 LYS A C 1 ATOM 2623 O O . LYS A 1 344 ? -29.250 7.669 -40.283 1.00 78.28 ? 340 LYS A O 1 ATOM 2624 C CB . LYS A 1 344 ? -25.956 6.901 -40.988 1.00 65.24 ? 340 LYS A CB 1 ATOM 2625 C CG . LYS A 1 344 ? -24.942 5.819 -40.607 1.00 85.16 ? 340 LYS A CG 1 ATOM 2626 C CD . LYS A 1 344 ? -25.265 5.178 -39.259 1.00 100.71 ? 340 LYS A CD 1 ATOM 2627 C CE . LYS A 1 344 ? -24.313 4.041 -38.931 1.00 92.34 ? 340 LYS A CE 1 ATOM 2628 N NZ . LYS A 1 344 ? -22.926 4.508 -38.671 1.00 87.23 ? 340 LYS A NZ 1 ATOM 2629 N N . THR A 1 345 ? -28.252 8.406 -42.163 1.00 60.81 ? 341 THR A N 1 ATOM 2630 C CA . THR A 1 345 ? -29.118 9.572 -42.292 1.00 67.77 ? 341 THR A CA 1 ATOM 2631 C C . THR A 1 345 ? -29.911 9.583 -43.593 1.00 58.93 ? 341 THR A C 1 ATOM 2632 O O . THR A 1 345 ? -29.351 9.469 -44.684 1.00 59.86 ? 341 THR A O 1 ATOM 2633 C CB . THR A 1 345 ? -28.309 10.879 -42.208 1.00 69.32 ? 341 THR A CB 1 ATOM 2634 O OG1 . THR A 1 345 ? -27.322 10.904 -43.246 1.00 52.07 ? 341 THR A OG1 1 ATOM 2635 C CG2 . THR A 1 345 ? -27.629 10.992 -40.858 1.00 68.77 ? 341 THR A CG2 1 ATOM 2636 N N . VAL A 1 346 ? -31.226 9.701 -43.451 1.00 60.81 ? 342 VAL A N 1 ATOM 2637 C CA . VAL A 1 346 ? -32.096 10.090 -44.549 1.00 61.90 ? 342 VAL A CA 1 ATOM 2638 C C . VAL A 1 346 ? -32.515 11.525 -44.264 1.00 58.63 ? 342 VAL A C 1 ATOM 2639 O O . VAL A 1 346 ? -32.939 11.836 -43.151 1.00 63.73 ? 342 VAL A O 1 ATOM 2640 C CB . VAL A 1 346 ? -33.333 9.181 -44.676 1.00 52.68 ? 342 VAL A CB 1 ATOM 2641 C CG1 . VAL A 1 346 ? -34.148 9.564 -45.911 1.00 40.91 ? 342 VAL A CG1 1 ATOM 2642 C CG2 . VAL A 1 346 ? -32.914 7.716 -44.733 1.00 62.80 ? 342 VAL A CG2 1 ATOM 2643 N N . SER A 1 347 ? -32.380 12.401 -45.254 1.00 51.84 ? 343 SER A N 1 ATOM 2644 C CA . SER A 1 347 ? -32.700 13.811 -45.061 1.00 54.31 ? 343 SER A CA 1 ATOM 2645 C C . SER A 1 347 ? -33.364 14.399 -46.296 1.00 56.15 ? 343 SER A C 1 ATOM 2646 O O . SER A 1 347 ? -33.219 13.876 -47.401 1.00 47.78 ? 343 SER A O 1 ATOM 2647 C CB . SER A 1 347 ? -31.440 14.607 -44.711 1.00 55.34 ? 343 SER A CB 1 ATOM 2648 O OG . SER A 1 347 ? -30.552 14.680 -45.812 1.00 66.61 ? 343 SER A OG 1 ATOM 2649 N N . TRP A 1 348 ? -34.082 15.499 -46.091 1.00 57.82 ? 344 TRP A N 1 ATOM 2650 C CA . TRP A 1 348 ? -34.886 16.115 -47.138 1.00 43.13 ? 344 TRP A CA 1 ATOM 2651 C C . TRP A 1 348 ? -34.345 17.478 -47.541 1.00 41.34 ? 344 TRP A C 1 ATOM 2652 O O . TRP A 1 348 ? -33.774 18.196 -46.720 1.00 44.42 ? 344 TRP A O 1 ATOM 2653 C CB . TRP A 1 348 ? -36.335 16.248 -46.675 1.00 42.44 ? 344 TRP A CB 1 ATOM 2654 C CG . TRP A 1 348 ? -37.067 14.949 -46.699 1.00 38.51 ? 344 TRP A CG 1 ATOM 2655 C CD1 . TRP A 1 348 ? -37.338 14.138 -45.636 1.00 52.31 ? 344 TRP A CD1 1 ATOM 2656 C CD2 . TRP A 1 348 ? -37.614 14.298 -47.850 1.00 39.63 ? 344 TRP A CD2 1 ATOM 2657 N NE1 . TRP A 1 348 ? -38.025 13.024 -46.055 1.00 52.79 ? 344 TRP A NE1 1 ATOM 2658 C CE2 . TRP A 1 348 ? -38.206 13.099 -47.411 1.00 41.62 ? 344 TRP A CE2 1 ATOM 2659 C CE3 . TRP A 1 348 ? -37.662 14.613 -49.210 1.00 42.73 ? 344 TRP A CE3 1 ATOM 2660 C CZ2 . TRP A 1 348 ? -38.837 12.220 -48.283 1.00 42.36 ? 344 TRP A CZ2 1 ATOM 2661 C CZ3 . TRP A 1 348 ? -38.290 13.738 -50.070 1.00 39.17 ? 344 TRP A CZ3 1 ATOM 2662 C CH2 . TRP A 1 348 ? -38.868 12.557 -49.605 1.00 38.35 ? 344 TRP A CH2 1 ATOM 2663 N N . MET A 1 349 ? -34.533 17.825 -48.811 1.00 35.94 ? 345 MET A N 1 ATOM 2664 C CA . MET A 1 349 ? -34.073 19.103 -49.342 1.00 39.02 ? 345 MET A CA 1 ATOM 2665 C C . MET A 1 349 ? -35.129 19.742 -50.241 1.00 48.14 ? 345 MET A C 1 ATOM 2666 O O . MET A 1 349 ? -35.898 19.045 -50.905 1.00 49.12 ? 345 MET A O 1 ATOM 2667 C CB . MET A 1 349 ? -32.770 18.917 -50.118 1.00 46.38 ? 345 MET A CB 1 ATOM 2668 C CG . MET A 1 349 ? -31.612 18.418 -49.271 1.00 56.31 ? 345 MET A CG 1 ATOM 2669 S SD . MET A 1 349 ? -30.279 19.623 -49.171 1.00 68.24 ? 345 MET A SD 1 ATOM 2670 C CE . MET A 1 349 ? -29.759 19.684 -50.882 1.00 36.64 ? 345 MET A CE 1 ATOM 2671 N N . LYS A 1 350 ? -35.155 21.072 -50.248 1.00 61.92 ? 346 LYS A N 1 ATOM 2672 C CA . LYS A 1 350 ? -36.115 21.839 -51.037 1.00 58.17 ? 346 LYS A CA 1 ATOM 2673 C C . LYS A 1 350 ? -35.409 22.890 -51.891 1.00 56.49 ? 346 LYS A C 1 ATOM 2674 O O . LYS A 1 350 ? -34.832 23.842 -51.363 1.00 62.98 ? 346 LYS A O 1 ATOM 2675 C CB . LYS A 1 350 ? -37.134 22.508 -50.111 1.00 53.30 ? 346 LYS A CB 1 ATOM 2676 C CG . LYS A 1 350 ? -38.097 23.461 -50.798 1.00 58.41 ? 346 LYS A CG 1 ATOM 2677 C CD . LYS A 1 350 ? -38.921 22.758 -51.863 1.00 56.39 ? 346 LYS A CD 1 ATOM 2678 C CE . LYS A 1 350 ? -40.121 23.594 -52.274 1.00 65.78 ? 346 LYS A CE 1 ATOM 2679 N NZ . LYS A 1 350 ? -39.720 24.920 -52.815 1.00 56.20 ? 346 LYS A NZ 1 ATOM 2680 N N . ASP A 1 351 ? -35.469 22.714 -53.209 1.00 56.17 ? 347 ASP A N 1 ATOM 2681 C CA . ASP A 1 351 ? -34.872 23.655 -54.157 1.00 65.09 ? 347 ASP A CA 1 ATOM 2682 C C . ASP A 1 351 ? -33.399 23.936 -53.845 1.00 63.76 ? 347 ASP A C 1 ATOM 2683 O O . ASP A 1 351 ? -32.893 25.025 -54.119 1.00 66.91 ? 347 ASP A O 1 ATOM 2684 C CB . ASP A 1 351 ? -35.668 24.967 -54.174 1.00 74.02 ? 347 ASP A CB 1 ATOM 2685 C CG . ASP A 1 351 ? -37.041 24.811 -54.807 1.00 66.70 ? 347 ASP A CG 1 ATOM 2686 O OD1 . ASP A 1 351 ? -37.215 23.907 -55.651 1.00 63.40 ? 347 ASP A OD1 1 ATOM 2687 O OD2 . ASP A 1 351 ? -37.947 25.600 -54.466 1.00 58.34 ? 347 ASP A OD2 1 ATOM 2688 N N . GLY A 1 352 ? -32.719 22.943 -53.278 1.00 67.25 ? 348 GLY A N 1 ATOM 2689 C CA . GLY A 1 352 ? -31.305 23.056 -52.965 1.00 60.41 ? 348 GLY A CA 1 ATOM 2690 C C . GLY A 1 352 ? -31.039 23.357 -51.500 1.00 54.96 ? 348 GLY A C 1 ATOM 2691 O O . GLY A 1 352 ? -29.945 23.096 -51.000 1.00 61.80 ? 348 GLY A O 1 ATOM 2692 N N . LYS A 1 353 ? -32.043 23.897 -50.812 1.00 64.57 ? 349 LYS A N 1 ATOM 2693 C CA . LYS A 1 353 ? -31.916 24.237 -49.396 1.00 71.58 ? 349 LYS A CA 1 ATOM 2694 C C . LYS A 1 353 ? -32.529 23.149 -48.518 1.00 54.08 ? 349 LYS A C 1 ATOM 2695 O O . LYS A 1 353 ? -33.544 22.548 -48.867 1.00 50.27 ? 349 LYS A O 1 ATOM 2696 C CB . LYS A 1 353 ? -32.572 25.590 -49.103 1.00 77.57 ? 349 LYS A CB 1 ATOM 2697 C CG . LYS A 1 353 ? -31.870 26.780 -49.756 1.00 72.68 ? 349 LYS A CG 1 ATOM 2698 C CD . LYS A 1 353 ? -30.559 27.131 -49.052 1.00 84.76 ? 349 LYS A CD 1 ATOM 2699 C CE . LYS A 1 353 ? -29.339 26.604 -49.798 1.00 94.43 ? 349 LYS A CE 1 ATOM 2700 N NZ . LYS A 1 353 ? -29.118 27.315 -51.087 1.00 105.87 ? 349 LYS A NZ 1 ATOM 2701 N N . ALA A 1 354 ? -31.901 22.905 -47.373 1.00 50.60 ? 350 ALA A N 1 ATOM 2702 C CA . ALA A 1 354 ? -32.258 21.779 -46.516 1.00 53.06 ? 350 ALA A CA 1 ATOM 2703 C C . ALA A 1 354 ? -33.550 21.984 -45.727 1.00 57.69 ? 350 ALA A C 1 ATOM 2704 O O . ALA A 1 354 ? -34.004 23.108 -45.519 1.00 66.53 ? 350 ALA A O 1 ATOM 2705 C CB . ALA A 1 354 ? -31.117 21.490 -45.553 1.00 71.11 ? 350 ALA A CB 1 ATOM 2706 N N . ILE A 1 355 ? -34.128 20.864 -45.304 1.00 75.58 ? 351 ILE A N 1 ATOM 2707 C CA . ILE A 1 355 ? -35.217 20.833 -44.334 1.00 80.04 ? 351 ILE A CA 1 ATOM 2708 C C . ILE A 1 355 ? -34.817 19.853 -43.252 1.00 93.41 ? 351 ILE A C 1 ATOM 2709 O O . ILE A 1 355 ? -34.526 18.696 -43.560 1.00 100.68 ? 351 ILE A O 1 ATOM 2710 C CB . ILE A 1 355 ? -36.552 20.360 -44.940 1.00 64.36 ? 351 ILE A CB 1 ATOM 2711 C CG1 . ILE A 1 355 ? -36.908 21.152 -46.196 1.00 63.73 ? 351 ILE A CG1 1 ATOM 2712 C CG2 . ILE A 1 355 ? -37.669 20.444 -43.896 1.00 60.11 ? 351 ILE A CG2 1 ATOM 2713 C CD1 . ILE A 1 355 ? -37.972 20.472 -47.027 1.00 47.31 ? 351 ILE A CD1 1 ATOM 2714 N N . GLY A 1 356 ? -34.779 20.277 -41.994 1.00 96.39 ? 352 GLY A N 1 ATOM 2715 C CA . GLY A 1 356 ? -34.475 19.308 -40.965 1.00 98.75 ? 352 GLY A CA 1 ATOM 2716 C C . GLY A 1 356 ? -35.621 18.320 -40.865 1.00 99.10 ? 352 GLY A C 1 ATOM 2717 O O . GLY A 1 356 ? -36.726 18.662 -40.442 1.00 97.83 ? 352 GLY A O 1 ATOM 2718 N N . HIS A 1 357 ? -35.343 17.084 -41.265 1.00 81.64 ? 353 HIS A N 1 ATOM 2719 C CA . HIS A 1 357 ? -36.140 15.925 -40.900 1.00 75.82 ? 353 HIS A CA 1 ATOM 2720 C C . HIS A 1 357 ? -35.244 14.706 -41.076 1.00 82.30 ? 353 HIS A C 1 ATOM 2721 O O . HIS A 1 357 ? -34.451 14.656 -42.018 1.00 93.46 ? 353 HIS A O 1 ATOM 2722 C CB . HIS A 1 357 ? -37.410 15.822 -41.755 1.00 84.69 ? 353 HIS A CB 1 ATOM 2723 C CG . HIS A 1 357 ? -38.641 16.354 -41.083 1.00 81.69 ? 353 HIS A CG 1 ATOM 2724 N ND1 . HIS A 1 357 ? -39.670 16.951 -41.779 1.00 84.22 ? 353 HIS A ND1 1 ATOM 2725 C CD2 . HIS A 1 357 ? -39.012 16.367 -39.780 1.00 71.15 ? 353 HIS A CD2 1 ATOM 2726 C CE1 . HIS A 1 357 ? -40.618 17.316 -40.933 1.00 93.03 ? 353 HIS A CE1 1 ATOM 2727 N NE2 . HIS A 1 357 ? -40.243 16.973 -39.714 1.00 84.70 ? 353 HIS A NE2 1 ATOM 2728 N N . SER A 1 358 ? -35.370 13.725 -40.189 1.00 75.13 ? 354 SER A N 1 ATOM 2729 C CA . SER A 1 358 ? -34.653 12.464 -40.341 1.00 80.78 ? 354 SER A CA 1 ATOM 2730 C C . SER A 1 358 ? -35.566 11.390 -40.923 1.00 83.02 ? 354 SER A C 1 ATOM 2731 O O . SER A 1 358 ? -35.144 10.252 -41.131 1.00 88.09 ? 354 SER A O 1 ATOM 2732 C CB . SER A 1 358 ? -34.079 12.007 -38.999 1.00 85.53 ? 354 SER A CB 1 ATOM 2733 O OG . SER A 1 358 ? -35.098 11.856 -38.028 1.00 108.22 ? 354 SER A OG 1 ATOM 2734 N N . GLU A 1 359 ? -36.816 11.759 -41.189 1.00 72.51 ? 355 GLU A N 1 ATOM 2735 C CA . GLU A 1 359 ? -37.838 10.788 -41.565 1.00 60.29 ? 355 GLU A CA 1 ATOM 2736 C C . GLU A 1 359 ? -37.897 10.559 -43.081 1.00 61.89 ? 355 GLU A C 1 ATOM 2737 O O . GLU A 1 359 ? -37.724 11.502 -43.855 1.00 50.08 ? 355 GLU A O 1 ATOM 2738 C CB . GLU A 1 359 ? -39.208 11.240 -41.047 1.00 79.97 ? 355 GLU A CB 1 ATOM 2739 C CG . GLU A 1 359 ? -39.615 12.652 -41.451 1.00 77.20 ? 355 GLU A CG 1 ATOM 2740 C CD . GLU A 1 359 ? -40.971 13.050 -40.893 1.00 96.88 ? 355 GLU A CD 1 ATOM 2741 O OE1 . GLU A 1 359 ? -41.767 12.150 -40.555 1.00 92.90 ? 355 GLU A OE1 1 ATOM 2742 O OE2 . GLU A 1 359 ? -41.238 14.266 -40.789 1.00 102.73 ? 355 GLU A OE2 1 ATOM 2743 N N . PRO A 1 360 ? -38.138 9.303 -43.512 1.00 59.82 ? 356 PRO A N 1 ATOM 2744 C CA . PRO A 1 360 ? -38.312 9.017 -44.943 1.00 50.94 ? 356 PRO A CA 1 ATOM 2745 C C . PRO A 1 360 ? -39.602 9.602 -45.508 1.00 50.96 ? 356 PRO A C 1 ATOM 2746 O O . PRO A 1 360 ? -39.740 9.699 -46.726 1.00 42.92 ? 356 PRO A O 1 ATOM 2747 C CB . PRO A 1 360 ? -38.354 7.482 -45.004 1.00 37.95 ? 356 PRO A CB 1 ATOM 2748 C CG . PRO A 1 360 ? -37.840 7.010 -43.691 1.00 44.48 ? 356 PRO A CG 1 ATOM 2749 C CD . PRO A 1 360 ? -38.200 8.070 -42.708 1.00 54.18 ? 356 PRO A CD 1 ATOM 2750 N N . VAL A 1 361 ? -40.536 9.963 -44.631 1.00 57.80 ? 357 VAL A N 1 ATOM 2751 C CA . VAL A 1 361 ? -41.822 10.513 -45.054 1.00 59.25 ? 357 VAL A CA 1 ATOM 2752 C C . VAL A 1 361 ? -41.886 12.010 -44.773 1.00 59.42 ? 357 VAL A C 1 ATOM 2753 O O . VAL A 1 361 ? -41.960 12.429 -43.618 1.00 62.20 ? 357 VAL A O 1 ATOM 2754 C CB . VAL A 1 361 ? -43.001 9.810 -44.342 1.00 57.47 ? 357 VAL A CB 1 ATOM 2755 C CG1 . VAL A 1 361 ? -44.340 10.412 -44.779 1.00 64.46 ? 357 VAL A CG1 1 ATOM 2756 C CG2 . VAL A 1 361 ? -42.969 8.312 -44.619 1.00 64.14 ? 357 VAL A CG2 1 ATOM 2757 N N . LEU A 1 362 ? -41.859 12.810 -45.835 1.00 49.39 ? 358 LEU A N 1 ATOM 2758 C CA . LEU A 1 362 ? -42.055 14.247 -45.709 1.00 58.47 ? 358 LEU A CA 1 ATOM 2759 C C . LEU A 1 362 ? -43.530 14.560 -45.874 1.00 60.42 ? 358 LEU A C 1 ATOM 2760 O O . LEU A 1 362 ? -44.129 14.217 -46.891 1.00 69.13 ? 358 LEU A O 1 ATOM 2761 C CB . LEU A 1 362 ? -41.242 15.022 -46.745 1.00 49.58 ? 358 LEU A CB 1 ATOM 2762 C CG . LEU A 1 362 ? -41.398 16.540 -46.613 1.00 60.52 ? 358 LEU A CG 1 ATOM 2763 C CD1 . LEU A 1 362 ? -40.547 17.066 -45.459 1.00 57.05 ? 358 LEU A CD1 1 ATOM 2764 C CD2 . LEU A 1 362 ? -41.069 17.243 -47.919 1.00 55.45 ? 358 LEU A CD2 1 ATOM 2765 N N . ARG A 1 363 ? -44.102 15.229 -44.880 1.00 59.50 ? 359 ARG A N 1 ATOM 2766 C CA . ARG A 1 363 ? -45.517 15.567 -44.906 1.00 71.16 ? 359 ARG A CA 1 ATOM 2767 C C . ARG A 1 363 ? -45.737 17.055 -44.691 1.00 82.26 ? 359 ARG A C 1 ATOM 2768 O O . ARG A 1 363 ? -45.466 17.589 -43.614 1.00 80.05 ? 359 ARG A O 1 ATOM 2769 C CB . ARG A 1 363 ? -46.272 14.765 -43.846 1.00 80.05 ? 359 ARG A CB 1 ATOM 2770 C CG . ARG A 1 363 ? -45.478 14.504 -42.576 1.00 80.18 ? 359 ARG A CG 1 ATOM 2771 C CD . ARG A 1 363 ? -46.303 13.712 -41.584 1.00 81.28 ? 359 ARG A CD 1 ATOM 2772 N NE . ARG A 1 363 ? -46.473 12.323 -42.008 1.00 68.35 ? 359 ARG A NE 1 ATOM 2773 C CZ . ARG A 1 363 ? -45.837 11.279 -41.480 1.00 69.52 ? 359 ARG A CZ 1 ATOM 2774 N NH1 . ARG A 1 363 ? -44.972 11.428 -40.484 1.00 88.37 ? 359 ARG A NH1 1 ATOM 2775 N NH2 . ARG A 1 363 ? -46.076 10.068 -41.952 1.00 63.74 ? 359 ARG A NH2 1 ATOM 2776 N N . ILE A 1 364 ? -46.227 17.714 -45.735 1.00 78.43 ? 360 ILE A N 1 ATOM 2777 C CA . ILE A 1 364 ? -46.713 19.080 -45.630 1.00 75.46 ? 360 ILE A CA 1 ATOM 2778 C C . ILE A 1 364 ? -48.226 19.007 -45.474 1.00 73.52 ? 360 ILE A C 1 ATOM 2779 O O . ILE A 1 364 ? -48.894 18.217 -46.142 1.00 81.52 ? 360 ILE A O 1 ATOM 2780 C CB . ILE A 1 364 ? -46.307 19.933 -46.850 1.00 72.52 ? 360 ILE A CB 1 ATOM 2781 C CG1 . ILE A 1 364 ? -44.808 20.254 -46.760 1.00 72.50 ? 360 ILE A CG1 1 ATOM 2782 C CG2 . ILE A 1 364 ? -47.140 21.220 -46.919 1.00 68.40 ? 360 ILE A CG2 1 ATOM 2783 C CD1 . ILE A 1 364 ? -44.274 21.175 -47.840 1.00 75.58 ? 360 ILE A CD1 1 ATOM 2784 N N . GLU A 1 365 ? -48.751 19.842 -44.586 1.00 71.21 ? 361 GLU A N 1 ATOM 2785 C CA . GLU A 1 365 ? -50.131 19.734 -44.128 1.00 73.72 ? 361 GLU A CA 1 ATOM 2786 C C . GLU A 1 365 ? -51.042 20.609 -44.979 1.00 68.71 ? 361 GLU A C 1 ATOM 2787 O O . GLU A 1 365 ? -51.970 20.116 -45.616 1.00 66.83 ? 361 GLU A O 1 ATOM 2788 C CB . GLU A 1 365 ? -50.231 20.121 -42.651 1.00 69.92 ? 361 GLU A CB 1 ATOM 2789 C CG . GLU A 1 365 ? -49.160 19.475 -41.766 1.00 77.94 ? 361 GLU A CG 1 ATOM 2790 C CD . GLU A 1 365 ? -47.813 20.179 -41.844 1.00 90.74 ? 361 GLU A CD 1 ATOM 2791 O OE1 . GLU A 1 365 ? -47.707 21.196 -42.563 1.00 89.60 ? 361 GLU A OE1 1 ATOM 2792 O OE2 . GLU A 1 365 ? -46.856 19.710 -41.192 1.00 90.68 ? 361 GLU A OE2 1 ATOM 2793 N N . SER A 1 366 ? -50.793 21.914 -44.958 1.00 57.37 ? 362 SER A N 1 ATOM 2794 C CA . SER A 1 366 ? -51.468 22.834 -45.864 1.00 60.18 ? 362 SER A CA 1 ATOM 2795 C C . SER A 1 366 ? -50.451 23.400 -46.847 1.00 59.52 ? 362 SER A C 1 ATOM 2796 O O . SER A 1 366 ? -49.475 24.039 -46.450 1.00 66.41 ? 362 SER A O 1 ATOM 2797 C CB . SER A 1 366 ? -52.162 23.958 -45.094 1.00 90.00 ? 362 SER A CB 1 ATOM 2798 O OG . SER A 1 366 ? -52.743 24.894 -45.986 1.00 87.54 ? 362 SER A OG 1 ATOM 2799 N N . VAL A 1 367 ? -50.678 23.147 -48.132 1.00 49.13 ? 363 VAL A N 1 ATOM 2800 C CA . VAL A 1 367 ? -49.796 23.644 -49.181 1.00 53.31 ? 363 VAL A CA 1 ATOM 2801 C C . VAL A 1 367 ? -49.853 25.164 -49.206 1.00 59.88 ? 363 VAL A C 1 ATOM 2802 O O . VAL A 1 367 ? -50.801 25.757 -48.707 1.00 58.69 ? 363 VAL A O 1 ATOM 2803 C CB . VAL A 1 367 ? -50.183 23.061 -50.566 1.00 47.83 ? 363 VAL A CB 1 ATOM 2804 C CG1 . VAL A 1 367 ? -49.630 23.904 -51.717 1.00 43.78 ? 363 VAL A CG1 1 ATOM 2805 C CG2 . VAL A 1 367 ? -49.684 21.631 -50.682 1.00 60.00 ? 363 VAL A CG2 1 ATOM 2806 N N . LYS A 1 368 ? -48.806 25.783 -49.742 1.00 70.16 ? 364 LYS A N 1 ATOM 2807 C CA . LYS A 1 368 ? -48.777 27.219 -49.985 1.00 55.93 ? 364 LYS A CA 1 ATOM 2808 C C . LYS A 1 368 ? -48.185 27.437 -51.373 1.00 50.01 ? 364 LYS A C 1 ATOM 2809 O O . LYS A 1 368 ? -47.626 26.510 -51.958 1.00 55.45 ? 364 LYS A O 1 ATOM 2810 C CB . LYS A 1 368 ? -47.951 27.945 -48.918 1.00 46.51 ? 364 LYS A CB 1 ATOM 2811 C CG . LYS A 1 368 ? -48.376 27.655 -47.481 1.00 53.27 ? 364 LYS A CG 1 ATOM 2812 C CD . LYS A 1 368 ? -47.180 27.574 -46.550 1.00 67.64 ? 364 LYS A CD 1 ATOM 2813 C CE . LYS A 1 368 ? -47.568 26.989 -45.204 1.00 63.95 ? 364 LYS A CE 1 ATOM 2814 N NZ . LYS A 1 368 ? -46.381 26.722 -44.348 1.00 77.13 ? 364 LYS A NZ 1 ATOM 2815 N N . LYS A 1 369 ? -48.313 28.645 -51.913 1.00 49.17 ? 365 LYS A N 1 ATOM 2816 C CA . LYS A 1 369 ? -47.624 28.973 -53.157 1.00 64.05 ? 365 LYS A CA 1 ATOM 2817 C C . LYS A 1 369 ? -46.119 28.906 -52.907 1.00 69.89 ? 365 LYS A C 1 ATOM 2818 O O . LYS A 1 369 ? -45.320 28.725 -53.828 1.00 59.49 ? 365 LYS A O 1 ATOM 2819 C CB . LYS A 1 369 ? -48.026 30.355 -53.674 1.00 71.16 ? 365 LYS A CB 1 ATOM 2820 C CG . LYS A 1 369 ? -47.652 30.579 -55.131 1.00 69.78 ? 365 LYS A CG 1 ATOM 2821 C CD . LYS A 1 369 ? -48.033 31.968 -55.615 1.00 90.36 ? 365 LYS A CD 1 ATOM 2822 C CE . LYS A 1 369 ? -47.085 33.030 -55.081 1.00 82.89 ? 365 LYS A CE 1 ATOM 2823 N NZ . LYS A 1 369 ? -47.348 34.362 -55.692 1.00 69.82 ? 365 LYS A NZ 1 ATOM 2824 N N . GLU A 1 370 ? -45.755 29.053 -51.637 1.00 69.88 ? 366 GLU A N 1 ATOM 2825 C CA . GLU A 1 370 ? -44.376 28.948 -51.181 1.00 51.71 ? 366 GLU A CA 1 ATOM 2826 C C . GLU A 1 370 ? -43.778 27.572 -51.463 1.00 57.13 ? 366 GLU A C 1 ATOM 2827 O O . GLU A 1 370 ? -42.644 27.457 -51.931 1.00 70.32 ? 366 GLU A O 1 ATOM 2828 C CB . GLU A 1 370 ? -44.318 29.235 -49.679 1.00 58.63 ? 366 GLU A CB 1 ATOM 2829 C CG . GLU A 1 370 ? -42.931 29.502 -49.130 1.00 87.38 ? 366 GLU A CG 1 ATOM 2830 C CD . GLU A 1 370 ? -42.950 29.784 -47.639 1.00 98.32 ? 366 GLU A CD 1 ATOM 2831 O OE1 . GLU A 1 370 ? -43.930 29.389 -46.970 1.00 70.52 ? 366 GLU A OE1 1 ATOM 2832 O OE2 . GLU A 1 370 ? -41.991 30.407 -47.136 1.00 110.43 ? 366 GLU A OE2 1 ATOM 2833 N N . ASP A 1 371 ? -44.559 26.533 -51.179 1.00 64.95 ? 367 ASP A N 1 ATOM 2834 C CA . ASP A 1 371 ? -44.068 25.156 -51.177 1.00 52.97 ? 367 ASP A CA 1 ATOM 2835 C C . ASP A 1 371 ? -43.805 24.592 -52.573 1.00 47.47 ? 367 ASP A C 1 ATOM 2836 O O . ASP A 1 371 ? -43.170 23.546 -52.710 1.00 54.19 ? 367 ASP A O 1 ATOM 2837 C CB . ASP A 1 371 ? -45.068 24.255 -50.446 1.00 42.45 ? 367 ASP A CB 1 ATOM 2838 C CG . ASP A 1 371 ? -45.191 24.595 -48.972 1.00 59.67 ? 367 ASP A CG 1 ATOM 2839 O OD1 . ASP A 1 371 ? -44.173 24.978 -48.355 1.00 61.90 ? 367 ASP A OD1 1 ATOM 2840 O OD2 . ASP A 1 371 ? -46.310 24.477 -48.428 1.00 57.03 ? 367 ASP A OD2 1 ATOM 2841 N N . LYS A 1 372 ? -44.289 25.278 -53.604 1.00 56.52 ? 368 LYS A N 1 ATOM 2842 C CA . LYS A 1 372 ? -44.061 24.842 -54.980 1.00 51.68 ? 368 LYS A CA 1 ATOM 2843 C C . LYS A 1 372 ? -42.569 24.816 -55.292 1.00 69.88 ? 368 LYS A C 1 ATOM 2844 O O . LYS A 1 372 ? -41.849 25.775 -55.012 1.00 80.41 ? 368 LYS A O 1 ATOM 2845 C CB . LYS A 1 372 ? -44.795 25.757 -55.967 1.00 69.88 ? 368 LYS A CB 1 ATOM 2846 C CG . LYS A 1 372 ? -44.298 25.685 -57.415 1.00 72.52 ? 368 LYS A CG 1 ATOM 2847 C CD . LYS A 1 372 ? -44.424 24.284 -58.005 1.00 72.87 ? 368 LYS A CD 1 ATOM 2848 C CE . LYS A 1 372 ? -43.733 24.185 -59.362 1.00 87.00 ? 368 LYS A CE 1 ATOM 2849 N NZ . LYS A 1 372 ? -44.608 24.634 -60.479 1.00 76.82 ? 368 LYS A NZ 1 ATOM 2850 N N . GLY A 1 373 ? -42.110 23.709 -55.867 1.00 65.09 ? 369 GLY A N 1 ATOM 2851 C CA . GLY A 1 373 ? -40.722 23.575 -56.260 1.00 62.65 ? 369 GLY A CA 1 ATOM 2852 C C . GLY A 1 373 ? -40.296 22.126 -56.367 1.00 62.45 ? 369 GLY A C 1 ATOM 2853 O O . GLY A 1 373 ? -41.125 21.232 -56.555 1.00 48.14 ? 369 GLY A O 1 ATOM 2854 N N . MET A 1 374 ? -38.991 21.903 -56.241 1.00 60.82 ? 370 MET A N 1 ATOM 2855 C CA . MET A 1 374 ? -38.406 20.574 -56.354 1.00 33.69 ? 370 MET A CA 1 ATOM 2856 C C . MET A 1 374 ? -37.998 20.047 -54.981 1.00 46.82 ? 370 MET A C 1 ATOM 2857 O O . MET A 1 374 ? -37.498 20.797 -54.142 1.00 49.05 ? 370 MET A O 1 ATOM 2858 C CB . MET A 1 374 ? -37.200 20.611 -57.290 1.00 30.44 ? 370 MET A CB 1 ATOM 2859 C CG . MET A 1 374 ? -37.545 21.000 -58.718 1.00 37.34 ? 370 MET A CG 1 ATOM 2860 S SD . MET A 1 374 ? -38.531 19.745 -59.551 1.00 47.90 ? 370 MET A SD 1 ATOM 2861 C CE . MET A 1 374 ? -37.365 18.388 -59.658 1.00 60.81 ? 370 MET A CE 1 ATOM 2862 N N . TYR A 1 375 ? -38.218 18.753 -54.765 1.00 51.74 ? 371 TYR A N 1 ATOM 2863 C CA . TYR A 1 375 ? -37.909 18.101 -53.495 1.00 40.34 ? 371 TYR A CA 1 ATOM 2864 C C . TYR A 1 375 ? -36.904 16.979 -53.704 1.00 51.94 ? 371 TYR A C 1 ATOM 2865 O O . TYR A 1 375 ? -36.880 16.344 -54.759 1.00 62.67 ? 371 TYR A O 1 ATOM 2866 C CB . TYR A 1 375 ? -39.182 17.551 -52.849 1.00 42.63 ? 371 TYR A CB 1 ATOM 2867 C CG . TYR A 1 375 ? -40.097 18.621 -52.293 1.00 43.47 ? 371 TYR A CG 1 ATOM 2868 C CD1 . TYR A 1 375 ? -40.787 19.480 -53.136 1.00 46.92 ? 371 TYR A CD1 1 ATOM 2869 C CD2 . TYR A 1 375 ? -40.270 18.771 -50.925 1.00 39.36 ? 371 TYR A CD2 1 ATOM 2870 C CE1 . TYR A 1 375 ? -41.622 20.461 -52.631 1.00 44.09 ? 371 TYR A CE1 1 ATOM 2871 C CE2 . TYR A 1 375 ? -41.104 19.748 -50.412 1.00 49.66 ? 371 TYR A CE2 1 ATOM 2872 C CZ . TYR A 1 375 ? -41.777 20.590 -51.269 1.00 45.88 ? 371 TYR A CZ 1 ATOM 2873 O OH . TYR A 1 375 ? -42.606 21.563 -50.758 1.00 38.56 ? 371 TYR A OH 1 ATOM 2874 N N . GLN A 1 376 ? -36.080 16.739 -52.690 1.00 51.10 ? 372 GLN A N 1 ATOM 2875 C CA . GLN A 1 376 ? -35.066 15.694 -52.753 1.00 44.70 ? 372 GLN A CA 1 ATOM 2876 C C . GLN A 1 376 ? -34.905 15.000 -51.412 1.00 44.78 ? 372 GLN A C 1 ATOM 2877 O O . GLN A 1 376 ? -35.004 15.636 -50.363 1.00 43.98 ? 372 GLN A O 1 ATOM 2878 C CB . GLN A 1 376 ? -33.721 16.276 -53.184 1.00 34.35 ? 372 GLN A CB 1 ATOM 2879 C CG . GLN A 1 376 ? -33.692 16.783 -54.605 1.00 36.28 ? 372 GLN A CG 1 ATOM 2880 C CD . GLN A 1 376 ? -32.379 16.486 -55.293 1.00 41.04 ? 372 GLN A CD 1 ATOM 2881 O OE1 . GLN A 1 376 ? -32.354 16.027 -56.435 1.00 55.20 ? 372 GLN A OE1 1 ATOM 2882 N NE2 . GLN A 1 376 ? -31.277 16.742 -54.601 1.00 36.27 ? 372 GLN A NE2 1 ATOM 2883 N N . CYS A 1 377 ? -34.658 13.694 -51.455 1.00 41.52 ? 373 CYS A N 1 ATOM 2884 C CA . CYS A 1 377 ? -34.285 12.947 -50.263 1.00 42.51 ? 373 CYS A CA 1 ATOM 2885 C C . CYS A 1 377 ? -32.838 12.502 -50.397 1.00 43.76 ? 373 CYS A C 1 ATOM 2886 O O . CYS A 1 377 ? -32.428 12.000 -51.445 1.00 48.12 ? 373 CYS A O 1 ATOM 2887 C CB . CYS A 1 377 ? -35.204 11.742 -50.050 1.00 63.68 ? 373 CYS A CB 1 ATOM 2888 S SG . CYS A 1 377 ? -35.000 10.397 -51.241 1.00 127.50 ? 373 CYS A SG 1 ATOM 2889 N N . PHE A 1 378 ? -32.066 12.708 -49.335 1.00 59.28 ? 374 PHE A N 1 ATOM 2890 C CA . PHE A 1 378 ? -30.656 12.344 -49.325 1.00 61.77 ? 374 PHE A CA 1 ATOM 2891 C C . PHE A 1 378 ? -30.398 11.210 -48.344 1.00 45.58 ? 374 PHE A C 1 ATOM 2892 O O . PHE A 1 378 ? -30.470 11.395 -47.129 1.00 43.89 ? 374 PHE A O 1 ATOM 2893 C CB . PHE A 1 378 ? -29.795 13.560 -48.978 1.00 60.93 ? 374 PHE A CB 1 ATOM 2894 C CG . PHE A 1 378 ? -29.091 14.156 -50.165 1.00 50.70 ? 374 PHE A CG 1 ATOM 2895 C CD1 . PHE A 1 378 ? -29.808 14.666 -51.231 1.00 32.81 ? 374 PHE A CD1 1 ATOM 2896 C CD2 . PHE A 1 378 ? -27.709 14.201 -50.214 1.00 56.22 ? 374 PHE A CD2 1 ATOM 2897 C CE1 . PHE A 1 378 ? -29.160 15.208 -52.322 1.00 40.57 ? 374 PHE A CE1 1 ATOM 2898 C CE2 . PHE A 1 378 ? -27.059 14.743 -51.302 1.00 46.86 ? 374 PHE A CE2 1 ATOM 2899 C CZ . PHE A 1 378 ? -27.785 15.246 -52.356 1.00 48.22 ? 374 PHE A CZ 1 ATOM 2900 N N . VAL A 1 379 ? -30.098 10.036 -48.890 1.00 51.90 ? 375 VAL A N 1 ATOM 2901 C CA . VAL A 1 379 ? -29.716 8.882 -48.091 1.00 63.12 ? 375 VAL A CA 1 ATOM 2902 C C . VAL A 1 379 ? -28.200 8.849 -48.018 1.00 56.37 ? 375 VAL A C 1 ATOM 2903 O O . VAL A 1 379 ? -27.524 9.095 -49.018 1.00 51.06 ? 375 VAL A O 1 ATOM 2904 C CB . VAL A 1 379 ? -30.257 7.566 -48.684 1.00 58.87 ? 375 VAL A CB 1 ATOM 2905 C CG1 . VAL A 1 379 ? -31.777 7.582 -48.677 1.00 53.62 ? 375 VAL A CG1 1 ATOM 2906 C CG2 . VAL A 1 379 ? -29.721 7.335 -50.102 1.00 55.68 ? 375 VAL A CG2 1 ATOM 2907 N N . ARG A 1 380 ? -27.663 8.573 -46.835 1.00 42.75 ? 376 ARG A N 1 ATOM 2908 C CA . ARG A 1 380 ? -26.223 8.642 -46.640 1.00 50.82 ? 376 ARG A CA 1 ATOM 2909 C C . ARG A 1 380 ? -25.701 7.647 -45.617 1.00 52.39 ? 376 ARG A C 1 ATOM 2910 O O . ARG A 1 380 ? -26.366 7.322 -44.632 1.00 45.56 ? 376 ARG A O 1 ATOM 2911 C CB . ARG A 1 380 ? -25.814 10.053 -46.206 1.00 65.10 ? 376 ARG A CB 1 ATOM 2912 C CG . ARG A 1 380 ? -26.143 11.150 -47.197 1.00 62.88 ? 376 ARG A CG 1 ATOM 2913 C CD . ARG A 1 380 ? -25.737 12.505 -46.657 1.00 61.32 ? 376 ARG A CD 1 ATOM 2914 N NE . ARG A 1 380 ? -25.589 13.495 -47.718 1.00 54.45 ? 376 ARG A NE 1 ATOM 2915 C CZ . ARG A 1 380 ? -24.486 13.661 -48.441 1.00 72.10 ? 376 ARG A CZ 1 ATOM 2916 N NH1 . ARG A 1 380 ? -23.421 12.901 -48.228 1.00 89.48 ? 376 ARG A NH1 1 ATOM 2917 N NH2 . ARG A 1 380 ? -24.448 14.590 -49.383 1.00 82.38 ? 376 ARG A NH2 1 ATOM 2918 N N . ASN A 1 381 ? -24.495 7.165 -45.885 1.00 59.64 ? 377 ASN A N 1 ATOM 2919 C CA . ASN A 1 381 ? -23.679 6.481 -44.899 1.00 58.88 ? 377 ASN A CA 1 ATOM 2920 C C . ASN A 1 381 ? -22.256 6.987 -45.103 1.00 55.27 ? 377 ASN A C 1 ATOM 2921 O O . ASN A 1 381 ? -21.986 7.672 -46.088 1.00 57.21 ? 377 ASN A O 1 ATOM 2922 C CB . ASN A 1 381 ? -23.776 4.963 -45.040 1.00 50.34 ? 377 ASN A CB 1 ATOM 2923 C CG . ASN A 1 381 ? -22.745 4.396 -45.989 1.00 55.28 ? 377 ASN A CG 1 ATOM 2924 O OD1 . ASN A 1 381 ? -22.964 4.338 -47.199 1.00 55.87 ? 377 ASN A OD1 1 ATOM 2925 N ND2 . ASN A 1 381 ? -21.615 3.961 -45.444 1.00 76.96 ? 377 ASN A ND2 1 ATOM 2926 N N . ASP A 1 382 ? -21.357 6.666 -44.180 1.00 43.64 ? 378 ASP A N 1 ATOM 2927 C CA . ASP A 1 382 ? -20.033 7.285 -44.145 1.00 51.87 ? 378 ASP A CA 1 ATOM 2928 C C . ASP A 1 382 ? -19.319 7.328 -45.498 1.00 60.13 ? 378 ASP A C 1 ATOM 2929 O O . ASP A 1 382 ? -18.737 8.350 -45.864 1.00 78.74 ? 378 ASP A O 1 ATOM 2930 C CB . ASP A 1 382 ? -19.150 6.548 -43.138 1.00 66.22 ? 378 ASP A CB 1 ATOM 2931 C CG . ASP A 1 382 ? -19.369 7.021 -41.715 1.00 83.91 ? 378 ASP A CG 1 ATOM 2932 O OD1 . ASP A 1 382 ? -18.694 7.987 -41.300 1.00 83.75 ? 378 ASP A OD1 1 ATOM 2933 O OD2 . ASP A 1 382 ? -20.213 6.427 -41.013 1.00 93.13 ? 378 ASP A OD2 1 ATOM 2934 N N . GLN A 1 383 ? -19.375 6.225 -46.240 1.00 43.45 ? 379 GLN A N 1 ATOM 2935 C CA . GLN A 1 383 ? -18.615 6.103 -47.481 1.00 45.92 ? 379 GLN A CA 1 ATOM 2936 C C . GLN A 1 383 ? -19.423 6.408 -48.746 1.00 38.65 ? 379 GLN A C 1 ATOM 2937 O O . GLN A 1 383 ? -18.882 6.337 -49.850 1.00 34.16 ? 379 GLN A O 1 ATOM 2938 C CB . GLN A 1 383 ? -18.032 4.691 -47.590 1.00 51.02 ? 379 GLN A CB 1 ATOM 2939 C CG . GLN A 1 383 ? -16.682 4.635 -48.296 1.00 57.43 ? 379 GLN A CG 1 ATOM 2940 C CD . GLN A 1 383 ? -15.570 5.262 -47.473 1.00 64.17 ? 379 GLN A CD 1 ATOM 2941 O OE1 . GLN A 1 383 ? -15.754 5.573 -46.296 1.00 61.84 ? 379 GLN A OE1 1 ATOM 2942 N NE2 . GLN A 1 383 ? -14.409 5.453 -48.090 1.00 82.82 ? 379 GLN A NE2 1 ATOM 2943 N N . GLU A 1 384 ? -20.705 6.741 -48.603 1.00 39.06 ? 380 GLU A N 1 ATOM 2944 C CA . GLU A 1 384 ? -21.576 6.836 -49.777 1.00 45.65 ? 380 GLU A CA 1 ATOM 2945 C C . GLU A 1 384 ? -22.823 7.702 -49.574 1.00 49.45 ? 380 GLU A C 1 ATOM 2946 O O . GLU A 1 384 ? -23.238 7.964 -48.448 1.00 57.81 ? 380 GLU A O 1 ATOM 2947 C CB . GLU A 1 384 ? -21.999 5.428 -50.199 1.00 48.55 ? 380 GLU A CB 1 ATOM 2948 C CG . GLU A 1 384 ? -22.443 5.308 -51.644 1.00 56.12 ? 380 GLU A CG 1 ATOM 2949 C CD . GLU A 1 384 ? -22.756 3.878 -52.036 1.00 54.37 ? 380 GLU A CD 1 ATOM 2950 O OE1 . GLU A 1 384 ? -23.242 3.665 -53.167 1.00 48.68 ? 380 GLU A OE1 1 ATOM 2951 O OE2 . GLU A 1 384 ? -22.515 2.967 -51.216 1.00 57.22 ? 380 GLU A OE2 1 ATOM 2952 N N . SER A 1 385 ? -23.417 8.133 -50.683 1.00 46.34 ? 381 SER A N 1 ATOM 2953 C CA . SER A 1 385 ? -24.663 8.896 -50.655 1.00 45.50 ? 381 SER A CA 1 ATOM 2954 C C . SER A 1 385 ? -25.392 8.758 -51.989 1.00 50.38 ? 381 SER A C 1 ATOM 2955 O O . SER A 1 385 ? -24.804 8.321 -52.977 1.00 54.08 ? 381 SER A O 1 ATOM 2956 C CB . SER A 1 385 ? -24.394 10.371 -50.349 1.00 50.36 ? 381 SER A CB 1 ATOM 2957 O OG . SER A 1 385 ? -23.651 10.985 -51.386 1.00 61.83 ? 381 SER A OG 1 ATOM 2958 N N . ALA A 1 386 ? -26.672 9.119 -52.018 1.00 45.58 ? 382 ALA A N 1 ATOM 2959 C CA . ALA A 1 386 ? -27.452 9.033 -53.250 1.00 33.29 ? 382 ALA A CA 1 ATOM 2960 C C . ALA A 1 386 ? -28.514 10.124 -53.318 1.00 43.39 ? 382 ALA A C 1 ATOM 2961 O O . ALA A 1 386 ? -28.909 10.684 -52.293 1.00 51.97 ? 382 ALA A O 1 ATOM 2962 C CB . ALA A 1 386 ? -28.098 7.656 -53.378 1.00 50.64 ? 382 ALA A CB 1 ATOM 2963 N N . GLU A 1 387 ? -28.967 10.413 -54.537 1.00 60.62 ? 383 GLU A N 1 ATOM 2964 C CA . GLU A 1 387 ? -29.947 11.469 -54.781 1.00 58.76 ? 383 GLU A CA 1 ATOM 2965 C C . GLU A 1 387 ? -31.087 11.008 -55.681 1.00 54.62 ? 383 GLU A C 1 ATOM 2966 O O . GLU A 1 387 ? -30.856 10.503 -56.789 1.00 75.72 ? 383 GLU A O 1 ATOM 2967 C CB . GLU A 1 387 ? -29.273 12.694 -55.410 1.00 46.14 ? 383 GLU A CB 1 ATOM 2968 C CG . GLU A 1 387 ? -30.199 13.552 -56.279 1.00 43.82 ? 383 GLU A CG 1 ATOM 2969 C CD . GLU A 1 387 ? -30.328 13.047 -57.706 1.00 58.18 ? 383 GLU A CD 1 ATOM 2970 O OE1 . GLU A 1 387 ? -29.319 12.576 -58.274 1.00 60.76 ? 383 GLU A OE1 1 ATOM 2971 O OE2 . GLU A 1 387 ? -31.443 13.126 -58.265 1.00 58.39 ? 383 GLU A OE2 1 ATOM 2972 N N . ALA A 1 388 ? -32.306 11.230 -55.189 1.00 47.50 ? 384 ALA A N 1 ATOM 2973 C CA . ALA A 1 388 ? -33.542 11.041 -55.945 1.00 64.66 ? 384 ALA A CA 1 ATOM 2974 C C . ALA A 1 388 ? -34.275 12.381 -56.073 1.00 55.33 ? 384 ALA A C 1 ATOM 2975 O O . ALA A 1 388 ? -34.304 13.172 -55.128 1.00 52.72 ? 384 ALA A O 1 ATOM 2976 C CB . ALA A 1 388 ? -34.436 10.005 -55.267 1.00 72.76 ? 384 ALA A CB 1 ATOM 2977 N N . SER A 1 389 ? -34.875 12.620 -57.237 1.00 59.88 ? 385 SER A N 1 ATOM 2978 C CA . SER A 1 389 ? -35.489 13.909 -57.555 1.00 52.14 ? 385 SER A CA 1 ATOM 2979 C C . SER A 1 389 ? -37.014 13.843 -57.527 1.00 60.82 ? 385 SER A C 1 ATOM 2980 O O . SER A 1 389 ? -37.605 12.803 -57.817 1.00 58.96 ? 385 SER A O 1 ATOM 2981 C CB . SER A 1 389 ? -35.025 14.388 -58.931 1.00 59.19 ? 385 SER A CB 1 ATOM 2982 O OG . SER A 1 389 ? -35.462 13.508 -59.951 1.00 69.23 ? 385 SER A OG 1 ATOM 2983 N N . ALA A 1 390 ? -37.644 14.960 -57.172 1.00 68.60 ? 386 ALA A N 1 ATOM 2984 C CA . ALA A 1 390 ? -39.102 15.043 -57.142 1.00 65.65 ? 386 ALA A CA 1 ATOM 2985 C C . ALA A 1 390 ? -39.576 16.464 -57.420 1.00 56.80 ? 386 ALA A C 1 ATOM 2986 O O . ALA A 1 390 ? -38.877 17.433 -57.120 1.00 61.20 ? 386 ALA A O 1 ATOM 2987 C CB . ALA A 1 390 ? -39.634 14.563 -55.801 1.00 58.94 ? 386 ALA A CB 1 ATOM 2988 N N . GLU A 1 391 ? -40.770 16.575 -57.996 1.00 60.80 ? 387 GLU A N 1 ATOM 2989 C CA . GLU A 1 391 ? -41.383 17.870 -58.274 1.00 56.54 ? 387 GLU A CA 1 ATOM 2990 C C . GLU A 1 391 ? -42.735 17.996 -57.592 1.00 54.10 ? 387 GLU A C 1 ATOM 2991 O O . GLU A 1 391 ? -43.455 17.011 -57.420 1.00 53.30 ? 387 GLU A O 1 ATOM 2992 C CB . GLU A 1 391 ? -41.555 18.083 -59.780 1.00 42.90 ? 387 GLU A CB 1 ATOM 2993 C CG . GLU A 1 391 ? -42.349 19.339 -60.127 1.00 40.77 ? 387 GLU A CG 1 ATOM 2994 C CD . GLU A 1 391 ? -42.276 19.695 -61.599 1.00 64.25 ? 387 GLU A CD 1 ATOM 2995 O OE1 . GLU A 1 391 ? -41.936 18.811 -62.413 1.00 66.89 ? 387 GLU A OE1 1 ATOM 2996 O OE2 . GLU A 1 391 ? -42.559 20.864 -61.940 1.00 59.39 ? 387 GLU A OE2 1 ATOM 2997 N N . LEU A 1 392 ? -43.067 19.223 -57.205 1.00 50.04 ? 388 LEU A N 1 ATOM 2998 C CA . LEU A 1 392 ? -44.398 19.551 -56.718 1.00 51.56 ? 388 LEU A CA 1 ATOM 2999 C C . LEU A 1 392 ? -45.032 20.536 -57.689 1.00 55.01 ? 388 LEU A C 1 ATOM 3000 O O . LEU A 1 392 ? -44.329 21.284 -58.367 1.00 64.89 ? 388 LEU A O 1 ATOM 3001 C CB . LEU A 1 392 ? -44.339 20.138 -55.307 1.00 47.40 ? 388 LEU A CB 1 ATOM 3002 C CG . LEU A 1 392 ? -45.685 20.529 -54.691 1.00 47.59 ? 388 LEU A CG 1 ATOM 3003 C CD1 . LEU A 1 392 ? -46.602 19.317 -54.547 1.00 48.65 ? 388 LEU A CD1 1 ATOM 3004 C CD2 . LEU A 1 392 ? -45.470 21.211 -53.349 1.00 59.90 ? 388 LEU A CD2 1 ATOM 3005 N N . LYS A 1 393 ? -46.357 20.520 -57.765 1.00 46.74 ? 389 LYS A N 1 ATOM 3006 C CA . LYS A 1 393 ? -47.087 21.432 -58.635 1.00 50.67 ? 389 LYS A CA 1 ATOM 3007 C C . LYS A 1 393 ? -48.323 21.963 -57.925 1.00 59.67 ? 389 LYS A C 1 ATOM 3008 O O . LYS A 1 393 ? -48.714 21.448 -56.876 1.00 55.03 ? 389 LYS A O 1 ATOM 3009 C CB . LYS A 1 393 ? -47.480 20.739 -59.939 1.00 49.23 ? 389 LYS A CB 1 ATOM 3010 C CG . LYS A 1 393 ? -46.312 20.478 -60.870 1.00 43.31 ? 389 LYS A CG 1 ATOM 3011 C CD . LYS A 1 393 ? -46.794 20.003 -62.225 1.00 30.33 ? 389 LYS A CD 1 ATOM 3012 C CE . LYS A 1 393 ? -45.687 20.045 -63.261 1.00 47.21 ? 389 LYS A CE 1 ATOM 3013 N NZ . LYS A 1 393 ? -46.190 19.672 -64.611 1.00 51.65 ? 389 LYS A NZ 1 ATOM 3014 N N . LEU A 1 394 ? -48.927 22.996 -58.504 1.00 71.01 ? 390 LEU A N 1 ATOM 3015 C CA . LEU A 1 394 ? -50.058 23.676 -57.886 1.00 65.36 ? 390 LEU A CA 1 ATOM 3016 C C . LEU A 1 394 ? -51.252 23.786 -58.825 1.00 64.81 ? 390 LEU A C 1 ATOM 3017 O O . LEU A 1 394 ? -51.112 23.682 -60.044 1.00 70.68 ? 390 LEU A O 1 ATOM 3018 C CB . LEU A 1 394 ? -49.633 25.067 -57.417 1.00 56.73 ? 390 LEU A CB 1 ATOM 3019 C CG . LEU A 1 394 ? -49.071 25.116 -55.997 1.00 58.77 ? 390 LEU A CG 1 ATOM 3020 C CD1 . LEU A 1 394 ? -48.333 26.420 -55.764 1.00 60.70 ? 390 LEU A CD1 1 ATOM 3021 C CD2 . LEU A 1 394 ? -50.189 24.944 -54.979 1.00 61.72 ? 390 LEU A CD2 1 ATOM 3022 N N . GLY A 1 395 ? -52.428 23.995 -58.240 1.00 75.36 ? 391 GLY A N 1 ATOM 3023 C CA . GLY A 1 395 ? -53.653 24.165 -58.999 1.00 88.81 ? 391 GLY A CA 1 ATOM 3024 C C . GLY A 1 395 ? -54.599 25.132 -58.314 1.00 86.24 ? 391 GLY A C 1 ATOM 3025 O O . GLY A 1 395 ? -54.580 25.271 -57.090 1.00 77.13 ? 391 GLY A O 1 ATOM 3026 N N . GLN B 1 5 ? -7.639 -34.659 14.870 1.00 102.90 ? 1 GLN B N 1 ATOM 3027 C CA . GLN B 1 5 ? -8.800 -34.040 15.568 1.00 108.53 ? 1 GLN B CA 1 ATOM 3028 C C . GLN B 1 5 ? -9.650 -33.201 14.614 1.00 108.75 ? 1 GLN B C 1 ATOM 3029 O O . GLN B 1 5 ? -10.876 -33.200 14.719 1.00 115.38 ? 1 GLN B O 1 ATOM 3030 C CB . GLN B 1 5 ? -8.318 -33.175 16.739 1.00 93.78 ? 1 GLN B CB 1 ATOM 3031 C CG . GLN B 1 5 ? -9.441 -32.522 17.537 1.00 108.47 ? 1 GLN B CG 1 ATOM 3032 C CD . GLN B 1 5 ? -8.944 -31.835 18.796 1.00 112.23 ? 1 GLN B CD 1 ATOM 3033 O OE1 . GLN B 1 5 ? -8.022 -32.314 19.456 1.00 113.51 ? 1 GLN B OE1 1 ATOM 3034 N NE2 . GLN B 1 5 ? -9.552 -30.702 19.132 1.00 113.93 ? 1 GLN B NE2 1 ATOM 3035 N N . LYS B 1 6 ? -8.998 -32.505 13.682 1.00 105.94 ? 2 LYS B N 1 ATOM 3036 C CA . LYS B 1 6 ? -9.682 -31.556 12.800 1.00 107.58 ? 2 LYS B CA 1 ATOM 3037 C C . LYS B 1 6 ? -9.286 -31.717 11.331 1.00 109.96 ? 2 LYS B C 1 ATOM 3038 O O . LYS B 1 6 ? -8.318 -32.404 11.009 1.00 103.43 ? 2 LYS B O 1 ATOM 3039 C CB . LYS B 1 6 ? -9.397 -30.123 13.253 1.00 111.85 ? 2 LYS B CB 1 ATOM 3040 C CG . LYS B 1 6 ? -9.688 -29.861 14.727 1.00 111.51 ? 2 LYS B CG 1 ATOM 3041 C CD . LYS B 1 6 ? -11.159 -30.066 15.096 1.00 110.52 ? 2 LYS B CD 1 ATOM 3042 C CE . LYS B 1 6 ? -12.047 -28.923 14.627 1.00 115.90 ? 2 LYS B CE 1 ATOM 3043 N NZ . LYS B 1 6 ? -12.536 -29.098 13.229 1.00 118.13 ? 2 LYS B NZ 1 ATOM 3044 N N . GLY B 1 7 ? -10.044 -31.065 10.451 1.00 117.24 ? 3 GLY B N 1 ATOM 3045 C CA . GLY B 1 7 ? -9.874 -31.218 9.015 1.00 116.29 ? 3 GLY B CA 1 ATOM 3046 C C . GLY B 1 7 ? -8.960 -30.198 8.350 1.00 117.89 ? 3 GLY B C 1 ATOM 3047 O O . GLY B 1 7 ? -8.555 -29.216 8.973 1.00 117.86 ? 3 GLY B O 1 ATOM 3048 N N . PRO B 1 8 ? -8.639 -30.432 7.065 1.00 114.03 ? 4 PRO B N 1 ATOM 3049 C CA . PRO B 1 8 ? -7.640 -29.731 6.244 1.00 113.42 ? 4 PRO B CA 1 ATOM 3050 C C . PRO B 1 8 ? -8.046 -28.374 5.655 1.00 112.03 ? 4 PRO B C 1 ATOM 3051 O O . PRO B 1 8 ? -9.229 -28.053 5.541 1.00 125.97 ? 4 PRO B O 1 ATOM 3052 C CB . PRO B 1 8 ? -7.393 -30.722 5.109 1.00 107.87 ? 4 PRO B CB 1 ATOM 3053 C CG . PRO B 1 8 ? -8.716 -31.376 4.917 1.00 102.24 ? 4 PRO B CG 1 ATOM 3054 C CD . PRO B 1 8 ? -9.324 -31.486 6.293 1.00 98.78 ? 4 PRO B CD 1 ATOM 3055 N N . VAL B 1 9 ? -7.029 -27.595 5.294 1.00 113.80 ? 5 VAL B N 1 ATOM 3056 C CA . VAL B 1 9 ? -7.175 -26.385 4.487 1.00 120.62 ? 5 VAL B CA 1 ATOM 3057 C C . VAL B 1 9 ? -5.804 -26.124 3.850 1.00 114.87 ? 5 VAL B C 1 ATOM 3058 O O . VAL B 1 9 ? -4.793 -26.606 4.358 1.00 115.37 ? 5 VAL B O 1 ATOM 3059 C CB . VAL B 1 9 ? -7.663 -25.166 5.321 1.00 118.76 ? 5 VAL B CB 1 ATOM 3060 C CG1 . VAL B 1 9 ? -6.652 -24.771 6.395 1.00 113.61 ? 5 VAL B CG1 1 ATOM 3061 C CG2 . VAL B 1 9 ? -7.976 -23.980 4.415 1.00 120.11 ? 5 VAL B CG2 1 ATOM 3062 N N . PHE B 1 10 ? -5.756 -25.359 2.761 1.00 113.14 ? 6 PHE B N 1 ATOM 3063 C CA . PHE B 1 10 ? -4.524 -25.234 1.976 1.00 109.68 ? 6 PHE B CA 1 ATOM 3064 C C . PHE B 1 10 ? -3.634 -24.079 2.432 1.00 123.95 ? 6 PHE B C 1 ATOM 3065 O O . PHE B 1 10 ? -3.978 -22.909 2.254 1.00 126.05 ? 6 PHE B O 1 ATOM 3066 C CB . PHE B 1 10 ? -4.866 -25.034 0.492 1.00 111.94 ? 6 PHE B CB 1 ATOM 3067 C CG . PHE B 1 10 ? -4.774 -26.287 -0.346 1.00 112.91 ? 6 PHE B CG 1 ATOM 3068 C CD1 . PHE B 1 10 ? -3.710 -27.164 -0.217 1.00 111.27 ? 6 PHE B CD1 1 ATOM 3069 C CD2 . PHE B 1 10 ? -5.754 -26.571 -1.282 1.00 115.50 ? 6 PHE B CD2 1 ATOM 3070 C CE1 . PHE B 1 10 ? -3.636 -28.304 -0.997 1.00 107.10 ? 6 PHE B CE1 1 ATOM 3071 C CE2 . PHE B 1 10 ? -5.681 -27.709 -2.062 1.00 94.18 ? 6 PHE B CE2 1 ATOM 3072 C CZ . PHE B 1 10 ? -4.623 -28.574 -1.919 1.00 92.59 ? 6 PHE B CZ 1 ATOM 3073 N N . LEU B 1 11 ? -2.488 -24.417 3.021 1.00 128.46 ? 7 LEU B N 1 ATOM 3074 C CA . LEU B 1 11 ? -1.476 -23.421 3.371 1.00 129.99 ? 7 LEU B CA 1 ATOM 3075 C C . LEU B 1 11 ? -0.590 -23.040 2.185 1.00 130.90 ? 7 LEU B C 1 ATOM 3076 O O . LEU B 1 11 ? -0.388 -21.856 1.912 1.00 121.15 ? 7 LEU B O 1 ATOM 3077 C CB . LEU B 1 11 ? -0.603 -23.931 4.521 1.00 133.73 ? 7 LEU B CB 1 ATOM 3078 C CG . LEU B 1 11 ? -0.912 -23.344 5.902 1.00 134.56 ? 7 LEU B CG 1 ATOM 3079 C CD1 . LEU B 1 11 ? -0.597 -21.852 5.942 1.00 124.76 ? 7 LEU B CD1 1 ATOM 3080 C CD2 . LEU B 1 11 ? -2.362 -23.599 6.290 1.00 128.87 ? 7 LEU B CD2 1 ATOM 3081 N N . LYS B 1 12 ? -0.076 -24.048 1.484 1.00 129.22 ? 8 LYS B N 1 ATOM 3082 C CA . LYS B 1 12 ? 0.837 -23.831 0.362 1.00 121.21 ? 8 LYS B CA 1 ATOM 3083 C C . LYS B 1 12 ? 0.205 -24.319 -0.938 1.00 114.63 ? 8 LYS B C 1 ATOM 3084 O O . LYS B 1 12 ? -0.071 -25.508 -1.105 1.00 109.13 ? 8 LYS B O 1 ATOM 3085 C CB . LYS B 1 12 ? 2.175 -24.535 0.608 1.00 121.45 ? 8 LYS B CB 1 ATOM 3086 C CG . LYS B 1 12 ? 2.962 -23.988 1.798 1.00 128.30 ? 8 LYS B CG 1 ATOM 3087 C CD . LYS B 1 12 ? 3.393 -22.542 1.583 1.00 123.12 ? 8 LYS B CD 1 ATOM 3088 C CE . LYS B 1 12 ? 4.219 -22.020 2.753 1.00 127.72 ? 8 LYS B CE 1 ATOM 3089 N NZ . LYS B 1 12 ? 5.504 -22.755 2.932 1.00 123.23 ? 8 LYS B NZ 1 ATOM 3090 N N . GLU B 1 13 ? -0.009 -23.379 -1.853 1.00 114.37 ? 9 GLU B N 1 ATOM 3091 C CA . GLU B 1 13 ? -0.802 -23.604 -3.055 1.00 109.75 ? 9 GLU B CA 1 ATOM 3092 C C . GLU B 1 13 ? -0.021 -23.174 -4.307 1.00 114.82 ? 9 GLU B C 1 ATOM 3093 O O . GLU B 1 13 ? -0.006 -21.991 -4.650 1.00 121.39 ? 9 GLU B O 1 ATOM 3094 C CB . GLU B 1 13 ? -2.129 -22.849 -2.938 1.00 114.24 ? 9 GLU B CB 1 ATOM 3095 C CG . GLU B 1 13 ? -3.338 -23.625 -3.439 1.00 117.07 ? 9 GLU B CG 1 ATOM 3096 C CD . GLU B 1 13 ? -4.652 -23.016 -2.977 1.00 122.03 ? 9 GLU B CD 1 ATOM 3097 O OE1 . GLU B 1 13 ? -4.623 -21.930 -2.359 1.00 118.26 ? 9 GLU B OE1 1 ATOM 3098 O OE2 . GLU B 1 13 ? -5.714 -23.622 -3.231 1.00 121.52 ? 9 GLU B OE2 1 ATOM 3099 N N . PRO B 1 14 ? 0.651 -24.130 -4.980 1.00 104.64 ? 10 PRO B N 1 ATOM 3100 C CA . PRO B 1 14 ? 1.575 -23.819 -6.082 1.00 89.31 ? 10 PRO B CA 1 ATOM 3101 C C . PRO B 1 14 ? 0.994 -22.919 -7.174 1.00 91.64 ? 10 PRO B C 1 ATOM 3102 O O . PRO B 1 14 ? -0.220 -22.874 -7.375 1.00 103.84 ? 10 PRO B O 1 ATOM 3103 C CB . PRO B 1 14 ? 1.903 -25.198 -6.660 1.00 91.56 ? 10 PRO B CB 1 ATOM 3104 C CG . PRO B 1 14 ? 1.732 -26.130 -5.526 1.00 92.62 ? 10 PRO B CG 1 ATOM 3105 C CD . PRO B 1 14 ? 0.600 -25.579 -4.709 1.00 94.89 ? 10 PRO B CD 1 ATOM 3106 N N . THR B 1 15 ? 1.884 -22.206 -7.860 1.00 103.97 ? 11 THR B N 1 ATOM 3107 C CA . THR B 1 15 ? 1.511 -21.212 -8.862 1.00 107.00 ? 11 THR B CA 1 ATOM 3108 C C . THR B 1 15 ? 0.616 -21.798 -9.951 1.00 104.09 ? 11 THR B C 1 ATOM 3109 O O . THR B 1 15 ? 0.745 -22.967 -10.314 1.00 108.45 ? 11 THR B O 1 ATOM 3110 C CB . THR B 1 15 ? 2.769 -20.599 -9.520 1.00 104.78 ? 11 THR B CB 1 ATOM 3111 O OG1 . THR B 1 15 ? 3.661 -20.126 -8.503 1.00 117.05 ? 11 THR B OG1 1 ATOM 3112 C CG2 . THR B 1 15 ? 2.400 -19.444 -10.443 1.00 92.17 ? 11 THR B CG2 1 ATOM 3113 N N . ASN B 1 16 ? -0.292 -20.970 -10.461 1.00 100.29 ? 12 ASN B N 1 ATOM 3114 C CA . ASN B 1 16 ? -1.276 -21.407 -11.447 1.00 100.38 ? 12 ASN B CA 1 ATOM 3115 C C . ASN B 1 16 ? -0.663 -21.883 -12.754 1.00 91.58 ? 12 ASN B C 1 ATOM 3116 O O . ASN B 1 16 ? -1.236 -22.727 -13.440 1.00 92.23 ? 12 ASN B O 1 ATOM 3117 C CB . ASN B 1 16 ? -2.260 -20.275 -11.752 1.00 102.14 ? 12 ASN B CB 1 ATOM 3118 C CG . ASN B 1 16 ? -3.170 -19.964 -10.589 1.00 110.91 ? 12 ASN B CG 1 ATOM 3119 O OD1 . ASN B 1 16 ? -3.276 -20.747 -9.651 1.00 114.59 ? 12 ASN B OD1 1 ATOM 3120 N ND2 . ASN B 1 16 ? -3.843 -18.821 -10.648 1.00 113.51 ? 12 ASN B ND2 1 ATOM 3121 N N . ARG B 1 17 ? 0.489 -21.324 -13.103 1.00 93.34 ? 13 ARG B N 1 ATOM 3122 C CA . ARG B 1 17 ? 1.152 -21.659 -14.355 1.00 92.03 ? 13 ARG B CA 1 ATOM 3123 C C . ARG B 1 17 ? 2.658 -21.758 -14.156 1.00 90.88 ? 13 ARG B C 1 ATOM 3124 O O . ARG B 1 17 ? 3.275 -20.879 -13.553 1.00 109.97 ? 13 ARG B O 1 ATOM 3125 C CB . ARG B 1 17 ? 0.810 -20.621 -15.425 1.00 99.69 ? 13 ARG B CB 1 ATOM 3126 C CG . ARG B 1 17 ? -0.655 -20.651 -15.834 1.00 106.29 ? 13 ARG B CG 1 ATOM 3127 C CD . ARG B 1 17 ? -1.012 -19.518 -16.775 1.00 127.55 ? 13 ARG B CD 1 ATOM 3128 N NE . ARG B 1 17 ? -1.026 -18.229 -16.091 1.00 141.69 ? 13 ARG B NE 1 ATOM 3129 C CZ . ARG B 1 17 ? -1.445 -17.094 -16.642 1.00 129.00 ? 13 ARG B CZ 1 ATOM 3130 N NH1 . ARG B 1 17 ? -1.890 -17.083 -17.891 1.00 117.63 ? 13 ARG B NH1 1 ATOM 3131 N NH2 . ARG B 1 17 ? -1.421 -15.969 -15.942 1.00 128.45 ? 13 ARG B NH2 1 ATOM 3132 N N . ILE B 1 18 ? 3.236 -22.843 -14.663 1.00 86.81 ? 14 ILE B N 1 ATOM 3133 C CA . ILE B 1 18 ? 4.655 -23.129 -14.484 1.00 93.56 ? 14 ILE B CA 1 ATOM 3134 C C . ILE B 1 18 ? 5.320 -23.426 -15.821 1.00 94.49 ? 14 ILE B C 1 ATOM 3135 O O . ILE B 1 18 ? 4.851 -24.267 -16.589 1.00 97.43 ? 14 ILE B O 1 ATOM 3136 C CB . ILE B 1 18 ? 4.869 -24.319 -13.529 1.00 94.53 ? 14 ILE B CB 1 ATOM 3137 C CG1 . ILE B 1 18 ? 4.248 -24.004 -12.164 1.00 96.13 ? 14 ILE B CG1 1 ATOM 3138 C CG2 . ILE B 1 18 ? 6.360 -24.639 -13.393 1.00 89.94 ? 14 ILE B CG2 1 ATOM 3139 C CD1 . ILE B 1 18 ? 4.314 -25.142 -11.168 1.00 101.57 ? 14 ILE B CD1 1 ATOM 3140 N N . ASP B 1 19 ? 6.423 -22.730 -16.078 1.00 93.15 ? 15 ASP B N 1 ATOM 3141 C CA . ASP B 1 19 ? 7.174 -22.884 -17.317 1.00 99.55 ? 15 ASP B CA 1 ATOM 3142 C C . ASP B 1 19 ? 8.654 -23.082 -17.008 1.00 98.07 ? 15 ASP B C 1 ATOM 3143 O O . ASP B 1 19 ? 9.152 -22.602 -15.989 1.00 102.58 ? 15 ASP B O 1 ATOM 3144 C CB . ASP B 1 19 ? 6.980 -21.660 -18.216 1.00 105.28 ? 15 ASP B CB 1 ATOM 3145 C CG . ASP B 1 19 ? 5.516 -21.345 -18.468 1.00 115.32 ? 15 ASP B CG 1 ATOM 3146 O OD1 . ASP B 1 19 ? 4.712 -22.292 -18.598 1.00 119.44 ? 15 ASP B OD1 1 ATOM 3147 O OD2 . ASP B 1 19 ? 5.170 -20.147 -18.536 1.00 113.43 ? 15 ASP B OD2 1 ATOM 3148 N N . PHE B 1 20 ? 9.351 -23.780 -17.900 1.00 90.91 ? 16 PHE B N 1 ATOM 3149 C CA . PHE B 1 20 ? 10.779 -24.039 -17.746 1.00 92.74 ? 16 PHE B CA 1 ATOM 3150 C C . PHE B 1 20 ? 11.313 -24.788 -18.960 1.00 98.84 ? 16 PHE B C 1 ATOM 3151 O O . PHE B 1 20 ? 10.545 -25.342 -19.746 1.00 98.86 ? 16 PHE B O 1 ATOM 3152 C CB . PHE B 1 20 ? 11.060 -24.842 -16.471 1.00 95.45 ? 16 PHE B CB 1 ATOM 3153 C CG . PHE B 1 20 ? 10.236 -26.095 -16.346 1.00 96.28 ? 16 PHE B CG 1 ATOM 3154 C CD1 . PHE B 1 20 ? 9.011 -26.075 -15.700 1.00 92.49 ? 16 PHE B CD1 1 ATOM 3155 C CD2 . PHE B 1 20 ? 10.689 -27.293 -16.870 1.00 95.30 ? 16 PHE B CD2 1 ATOM 3156 C CE1 . PHE B 1 20 ? 8.254 -27.227 -15.583 1.00 89.26 ? 16 PHE B CE1 1 ATOM 3157 C CE2 . PHE B 1 20 ? 9.935 -28.446 -16.755 1.00 81.53 ? 16 PHE B CE2 1 ATOM 3158 C CZ . PHE B 1 20 ? 8.718 -28.412 -16.112 1.00 80.42 ? 16 PHE B CZ 1 ATOM 3159 N N . SER B 1 21 ? 12.635 -24.803 -19.103 1.00 103.15 ? 17 SER B N 1 ATOM 3160 C CA . SER B 1 21 ? 13.281 -25.402 -20.265 1.00 93.66 ? 17 SER B CA 1 ATOM 3161 C C . SER B 1 21 ? 13.668 -26.854 -20.007 1.00 87.96 ? 17 SER B C 1 ATOM 3162 O O . SER B 1 21 ? 13.442 -27.381 -18.916 1.00 85.43 ? 17 SER B O 1 ATOM 3163 C CB . SER B 1 21 ? 14.520 -24.593 -20.654 1.00 98.85 ? 17 SER B CB 1 ATOM 3164 O OG . SER B 1 21 ? 15.429 -24.501 -19.571 1.00 91.37 ? 17 SER B OG 1 ATOM 3165 N N . ASN B 1 22 ? 14.251 -27.493 -21.017 1.00 90.38 ? 18 ASN B N 1 ATOM 3166 C CA . ASN B 1 22 ? 14.699 -28.875 -20.898 1.00 90.31 ? 18 ASN B CA 1 ATOM 3167 C C . ASN B 1 22 ? 16.011 -28.965 -20.125 1.00 95.01 ? 18 ASN B C 1 ATOM 3168 O O . ASN B 1 22 ? 16.305 -29.984 -19.501 1.00 103.32 ? 18 ASN B O 1 ATOM 3169 C CB . ASN B 1 22 ? 14.854 -29.509 -22.285 1.00 89.89 ? 18 ASN B CB 1 ATOM 3170 C CG . ASN B 1 22 ? 15.970 -28.878 -23.101 1.00 92.80 ? 18 ASN B CG 1 ATOM 3171 O OD1 . ASN B 1 22 ? 16.245 -27.685 -22.979 1.00 107.12 ? 18 ASN B OD1 1 ATOM 3172 N ND2 . ASN B 1 22 ? 16.619 -29.683 -23.941 1.00 87.81 ? 18 ASN B ND2 1 ATOM 3173 N N . SER B 1 23 ? 16.792 -27.889 -20.167 1.00 92.66 ? 19 SER B N 1 ATOM 3174 C CA . SER B 1 23 ? 18.085 -27.844 -19.492 1.00 89.70 ? 19 SER B CA 1 ATOM 3175 C C . SER B 1 23 ? 17.942 -27.565 -18.000 1.00 88.42 ? 19 SER B C 1 ATOM 3176 O O . SER B 1 23 ? 18.680 -28.116 -17.183 1.00 105.19 ? 19 SER B O 1 ATOM 3177 C CB . SER B 1 23 ? 18.982 -26.781 -20.129 1.00 96.51 ? 19 SER B CB 1 ATOM 3178 O OG . SER B 1 23 ? 18.409 -25.493 -19.999 1.00 109.96 ? 19 SER B OG 1 ATOM 3179 N N . THR B 1 24 ? 16.986 -26.711 -17.653 1.00 82.58 ? 20 THR B N 1 ATOM 3180 C CA . THR B 1 24 ? 16.825 -26.264 -16.274 1.00 87.13 ? 20 THR B CA 1 ATOM 3181 C C . THR B 1 24 ? 16.228 -27.362 -15.401 1.00 100.68 ? 20 THR B C 1 ATOM 3182 O O . THR B 1 24 ? 16.888 -27.877 -14.498 1.00 110.98 ? 20 THR B O 1 ATOM 3183 C CB . THR B 1 24 ? 15.923 -25.011 -16.187 1.00 92.14 ? 20 THR B CB 1 ATOM 3184 O OG1 . THR B 1 24 ? 16.442 -23.981 -17.036 1.00 102.03 ? 20 THR B OG1 1 ATOM 3185 C CG2 . THR B 1 24 ? 15.846 -24.492 -14.753 1.00 87.99 ? 20 THR B CG2 1 ATOM 3186 N N . GLY B 1 25 ? 14.978 -27.716 -15.684 1.00 92.98 ? 21 GLY B N 1 ATOM 3187 C CA . GLY B 1 25 ? 14.222 -28.623 -14.840 1.00 79.53 ? 21 GLY B CA 1 ATOM 3188 C C . GLY B 1 25 ? 13.314 -27.803 -13.948 1.00 82.27 ? 21 GLY B C 1 ATOM 3189 O O . GLY B 1 25 ? 13.251 -26.582 -14.089 1.00 89.83 ? 21 GLY B O 1 ATOM 3190 N N . ALA B 1 26 ? 12.633 -28.460 -13.015 1.00 86.91 ? 22 ALA B N 1 ATOM 3191 C CA . ALA B 1 26 ? 11.680 -27.780 -12.144 1.00 97.21 ? 22 ALA B CA 1 ATOM 3192 C C . ALA B 1 26 ? 11.119 -28.742 -11.110 1.00 100.61 ? 22 ALA B C 1 ATOM 3193 O O . ALA B 1 26 ? 11.249 -29.958 -11.243 1.00 99.45 ? 22 ALA B O 1 ATOM 3194 C CB . ALA B 1 26 ? 10.542 -27.167 -12.960 1.00 92.95 ? 22 ALA B CB 1 ATOM 3195 N N . GLU B 1 27 ? 10.497 -28.185 -10.077 1.00 96.83 ? 23 GLU B N 1 ATOM 3196 C CA . GLU B 1 27 ? 9.907 -28.983 -9.013 1.00 97.86 ? 23 GLU B CA 1 ATOM 3197 C C . GLU B 1 27 ? 8.814 -28.199 -8.298 1.00 96.74 ? 23 GLU B C 1 ATOM 3198 O O . GLU B 1 27 ? 8.796 -26.968 -8.333 1.00 86.87 ? 23 GLU B O 1 ATOM 3199 C CB . GLU B 1 27 ? 10.985 -29.433 -8.023 1.00 103.27 ? 23 GLU B CB 1 ATOM 3200 C CG . GLU B 1 27 ? 11.902 -28.316 -7.529 1.00 111.62 ? 23 GLU B CG 1 ATOM 3201 C CD . GLU B 1 27 ? 13.299 -28.812 -7.193 1.00 111.14 ? 23 GLU B CD 1 ATOM 3202 O OE1 . GLU B 1 27 ? 13.936 -29.440 -8.066 1.00 99.63 ? 23 GLU B OE1 1 ATOM 3203 O OE2 . GLU B 1 27 ? 13.761 -28.574 -6.057 1.00 103.71 ? 23 GLU B OE2 1 ATOM 3204 N N . ILE B 1 28 ? 7.911 -28.925 -7.645 1.00 96.78 ? 24 ILE B N 1 ATOM 3205 C CA . ILE B 1 28 ? 6.754 -28.324 -6.992 1.00 99.55 ? 24 ILE B CA 1 ATOM 3206 C C . ILE B 1 28 ? 6.553 -28.952 -5.619 1.00 101.59 ? 24 ILE B C 1 ATOM 3207 O O . ILE B 1 28 ? 6.937 -30.100 -5.392 1.00 104.91 ? 24 ILE B O 1 ATOM 3208 C CB . ILE B 1 28 ? 5.458 -28.505 -7.822 1.00 96.59 ? 24 ILE B CB 1 ATOM 3209 C CG1 . ILE B 1 28 ? 5.741 -28.384 -9.326 1.00 89.97 ? 24 ILE B CG1 1 ATOM 3210 C CG2 . ILE B 1 28 ? 4.406 -27.487 -7.386 1.00 100.43 ? 24 ILE B CG2 1 ATOM 3211 C CD1 . ILE B 1 28 ? 4.571 -28.783 -10.203 1.00 95.25 ? 24 ILE B CD1 1 ATOM 3212 N N . GLU B 1 29 ? 5.951 -28.194 -4.707 1.00 103.28 ? 25 GLU B N 1 ATOM 3213 C CA . GLU B 1 29 ? 5.668 -28.686 -3.364 1.00 111.15 ? 25 GLU B CA 1 ATOM 3214 C C . GLU B 1 29 ? 4.304 -28.204 -2.883 1.00 109.32 ? 25 GLU B C 1 ATOM 3215 O O . GLU B 1 29 ? 3.957 -27.032 -3.036 1.00 103.53 ? 25 GLU B O 1 ATOM 3216 C CB . GLU B 1 29 ? 6.758 -28.241 -2.391 1.00 118.44 ? 25 GLU B CB 1 ATOM 3217 C CG . GLU B 1 29 ? 6.650 -28.883 -1.018 1.00 126.14 ? 25 GLU B CG 1 ATOM 3218 C CD . GLU B 1 29 ? 7.866 -28.620 -0.149 1.00 135.91 ? 25 GLU B CD 1 ATOM 3219 O OE1 . GLU B 1 29 ? 8.811 -27.954 -0.623 1.00 134.67 ? 25 GLU B OE1 1 ATOM 3220 O OE2 . GLU B 1 29 ? 7.878 -29.083 1.012 1.00 132.94 ? 25 GLU B OE2 1 ATOM 3221 N N . CYS B 1 30 ? 3.538 -29.126 -2.306 1.00 120.67 ? 26 CYS B N 1 ATOM 3222 C CA . CYS B 1 30 ? 2.183 -28.846 -1.847 1.00 115.19 ? 26 CYS B CA 1 ATOM 3223 C C . CYS B 1 30 ? 1.929 -29.461 -0.468 1.00 123.67 ? 26 CYS B C 1 ATOM 3224 O O . CYS B 1 30 ? 2.023 -30.678 -0.299 1.00 130.31 ? 26 CYS B O 1 ATOM 3225 C CB . CYS B 1 30 ? 1.174 -29.374 -2.875 1.00 118.29 ? 26 CYS B CB 1 ATOM 3226 S SG . CYS B 1 30 ? -0.340 -30.105 -2.203 1.00 122.31 ? 26 CYS B SG 1 ATOM 3227 N N . LYS B 1 31 ? 1.627 -28.613 0.515 1.00 118.92 ? 27 LYS B N 1 ATOM 3228 C CA . LYS B 1 31 ? 1.176 -29.075 1.827 1.00 123.02 ? 27 LYS B CA 1 ATOM 3229 C C . LYS B 1 31 ? -0.259 -28.610 2.030 1.00 126.76 ? 27 LYS B C 1 ATOM 3230 O O . LYS B 1 31 ? -0.772 -27.847 1.210 1.00 118.93 ? 27 LYS B O 1 ATOM 3231 C CB . LYS B 1 31 ? 2.065 -28.514 2.940 1.00 120.86 ? 27 LYS B CB 1 ATOM 3232 C CG . LYS B 1 31 ? 3.560 -28.550 2.654 1.00 115.60 ? 27 LYS B CG 1 ATOM 3233 C CD . LYS B 1 31 ? 4.360 -27.988 3.825 1.00 122.37 ? 27 LYS B CD 1 ATOM 3234 C CE . LYS B 1 31 ? 4.217 -26.475 3.947 1.00 116.73 ? 27 LYS B CE 1 ATOM 3235 N NZ . LYS B 1 31 ? 4.805 -25.955 5.210 1.00 110.25 ? 27 LYS B NZ 1 ATOM 3236 N N . ALA B 1 32 ? -0.919 -29.060 3.097 1.00 122.64 ? 28 ALA B N 1 ATOM 3237 C CA . ALA B 1 32 ? -2.147 -28.392 3.519 1.00 119.44 ? 28 ALA B CA 1 ATOM 3238 C C . ALA B 1 32 ? -2.214 -28.071 5.016 1.00 121.23 ? 28 ALA B C 1 ATOM 3239 O O . ALA B 1 32 ? -1.801 -26.993 5.443 1.00 117.45 ? 28 ALA B O 1 ATOM 3240 C CB . ALA B 1 32 ? -3.344 -29.249 3.118 1.00 117.31 ? 28 ALA B CB 1 ATOM 3241 N N . SER B 1 33 ? -2.687 -29.041 5.801 1.00 123.42 ? 29 SER B N 1 ATOM 3242 C CA . SER B 1 33 ? -2.992 -28.842 7.223 1.00 120.99 ? 29 SER B CA 1 ATOM 3243 C C . SER B 1 33 ? -3.791 -30.022 7.769 1.00 111.75 ? 29 SER B C 1 ATOM 3244 O O . SER B 1 33 ? -4.126 -30.948 7.032 1.00 97.53 ? 29 SER B O 1 ATOM 3245 C CB . SER B 1 33 ? -3.782 -27.557 7.455 1.00 118.63 ? 29 SER B CB 1 ATOM 3246 O OG . SER B 1 33 ? -4.907 -27.508 6.605 1.00 123.30 ? 29 SER B OG 1 ATOM 3247 N N . GLY B 1 34 ? -4.102 -29.975 9.063 1.00 102.25 ? 30 GLY B N 1 ATOM 3248 C CA . GLY B 1 34 ? -5.169 -30.792 9.620 1.00 100.13 ? 30 GLY B CA 1 ATOM 3249 C C . GLY B 1 34 ? -4.697 -31.998 10.399 1.00 105.57 ? 30 GLY B C 1 ATOM 3250 O O . GLY B 1 34 ? -3.505 -32.155 10.647 1.00 116.91 ? 30 GLY B O 1 ATOM 3251 N N . ASN B 1 35 ? -5.640 -32.845 10.803 1.00 99.34 ? 31 ASN B N 1 ATOM 3252 C CA . ASN B 1 35 ? -5.306 -34.066 11.525 1.00 113.34 ? 31 ASN B CA 1 ATOM 3253 C C . ASN B 1 35 ? -6.198 -35.241 11.117 1.00 110.97 ? 31 ASN B C 1 ATOM 3254 O O . ASN B 1 35 ? -7.394 -35.058 10.891 1.00 117.79 ? 31 ASN B O 1 ATOM 3255 C CB . ASN B 1 35 ? -5.416 -33.828 13.029 1.00 112.40 ? 31 ASN B CB 1 ATOM 3256 C CG . ASN B 1 35 ? -4.220 -33.088 13.587 1.00 111.17 ? 31 ASN B CG 1 ATOM 3257 O OD1 . ASN B 1 35 ? -4.319 -31.927 13.984 1.00 108.80 ? 31 ASN B OD1 1 ATOM 3258 N ND2 . ASN B 1 35 ? -3.078 -33.763 13.621 1.00 110.53 ? 31 ASN B ND2 1 ATOM 3259 N N . PRO B 1 36 ? -5.622 -36.454 11.016 1.00 110.80 ? 32 PRO B N 1 ATOM 3260 C CA . PRO B 1 36 ? -4.190 -36.763 11.136 1.00 121.80 ? 32 PRO B CA 1 ATOM 3261 C C . PRO B 1 36 ? -3.391 -36.178 9.971 1.00 121.52 ? 32 PRO B C 1 ATOM 3262 O O . PRO B 1 36 ? -3.967 -35.440 9.170 1.00 117.19 ? 32 PRO B O 1 ATOM 3263 C CB . PRO B 1 36 ? -4.156 -38.294 11.119 1.00 128.30 ? 32 PRO B CB 1 ATOM 3264 C CG . PRO B 1 36 ? -5.387 -38.688 10.382 1.00 114.04 ? 32 PRO B CG 1 ATOM 3265 C CD . PRO B 1 36 ? -6.419 -37.666 10.756 1.00 108.53 ? 32 PRO B CD 1 ATOM 3266 N N . MET B 1 37 ? -2.101 -36.492 9.879 1.00 123.74 ? 33 MET B N 1 ATOM 3267 C CA . MET B 1 37 ? -1.273 -35.960 8.800 1.00 122.92 ? 33 MET B CA 1 ATOM 3268 C C . MET B 1 37 ? -1.929 -36.315 7.466 1.00 122.00 ? 33 MET B C 1 ATOM 3269 O O . MET B 1 37 ? -2.055 -37.493 7.132 1.00 131.75 ? 33 MET B O 1 ATOM 3270 C CB . MET B 1 37 ? 0.154 -36.524 8.885 1.00 120.49 ? 33 MET B CB 1 ATOM 3271 C CG . MET B 1 37 ? 0.929 -36.555 7.566 1.00 118.17 ? 33 MET B CG 1 ATOM 3272 S SD . MET B 1 37 ? 1.118 -34.945 6.775 1.00 140.86 ? 33 MET B SD 1 ATOM 3273 C CE . MET B 1 37 ? 2.353 -34.181 7.822 1.00 121.11 ? 33 MET B CE 1 ATOM 3274 N N . PRO B 1 38 ? -2.357 -35.296 6.698 1.00 115.34 ? 34 PRO B N 1 ATOM 3275 C CA . PRO B 1 38 ? -3.160 -35.576 5.502 1.00 112.32 ? 34 PRO B CA 1 ATOM 3276 C C . PRO B 1 38 ? -2.394 -36.321 4.421 1.00 111.72 ? 34 PRO B C 1 ATOM 3277 O O . PRO B 1 38 ? -1.182 -36.147 4.294 1.00 115.47 ? 34 PRO B O 1 ATOM 3278 C CB . PRO B 1 38 ? -3.557 -34.179 5.015 1.00 113.90 ? 34 PRO B CB 1 ATOM 3279 C CG . PRO B 1 38 ? -2.475 -33.293 5.521 1.00 122.25 ? 34 PRO B CG 1 ATOM 3280 C CD . PRO B 1 38 ? -2.148 -33.848 6.875 1.00 117.91 ? 34 PRO B CD 1 ATOM 3281 N N . GLU B 1 39 ? -3.101 -37.141 3.651 1.00 114.04 ? 35 GLU B N 1 ATOM 3282 C CA . GLU B 1 39 ? -2.488 -37.825 2.526 1.00 118.65 ? 35 GLU B CA 1 ATOM 3283 C C . GLU B 1 39 ? -2.384 -36.837 1.379 1.00 117.12 ? 35 GLU B C 1 ATOM 3284 O O . GLU B 1 39 ? -3.399 -36.375 0.861 1.00 111.09 ? 35 GLU B O 1 ATOM 3285 C CB . GLU B 1 39 ? -3.315 -39.041 2.105 1.00 122.44 ? 35 GLU B CB 1 ATOM 3286 C CG . GLU B 1 39 ? -3.687 -39.974 3.244 1.00 128.27 ? 35 GLU B CG 1 ATOM 3287 C CD . GLU B 1 39 ? -4.580 -41.113 2.791 1.00 111.78 ? 35 GLU B CD 1 ATOM 3288 O OE1 . GLU B 1 39 ? -4.909 -41.169 1.586 1.00 103.35 ? 35 GLU B OE1 1 ATOM 3289 O OE2 . GLU B 1 39 ? -4.956 -41.951 3.637 1.00 109.90 ? 35 GLU B OE2 1 ATOM 3290 N N . ILE B 1 40 ? -1.159 -36.530 0.968 1.00 123.48 ? 36 ILE B N 1 ATOM 3291 C CA . ILE B 1 40 ? -0.949 -35.585 -0.117 1.00 116.33 ? 36 ILE B CA 1 ATOM 3292 C C . ILE B 1 40 ? -0.811 -36.368 -1.410 1.00 113.22 ? 36 ILE B C 1 ATOM 3293 O O . ILE B 1 40 ? 0.180 -37.066 -1.626 1.00 113.42 ? 36 ILE B O 1 ATOM 3294 C CB . ILE B 1 40 ? 0.295 -34.709 0.116 1.00 123.97 ? 36 ILE B CB 1 ATOM 3295 C CG1 . ILE B 1 40 ? 0.269 -34.118 1.530 1.00 123.39 ? 36 ILE B CG1 1 ATOM 3296 C CG2 . ILE B 1 40 ? 0.372 -33.602 -0.930 1.00 122.90 ? 36 ILE B CG2 1 ATOM 3297 C CD1 . ILE B 1 40 ? -1.000 -33.335 1.860 1.00 114.95 ? 36 ILE B CD1 1 ATOM 3298 N N . ILE B 1 41 ? -1.821 -36.240 -2.264 1.00 111.35 ? 37 ILE B N 1 ATOM 3299 C CA . ILE B 1 41 ? -1.871 -36.976 -3.518 1.00 112.07 ? 37 ILE B CA 1 ATOM 3300 C C . ILE B 1 41 ? -1.849 -36.009 -4.687 1.00 107.05 ? 37 ILE B C 1 ATOM 3301 O O . ILE B 1 41 ? -2.545 -34.993 -4.685 1.00 105.17 ? 37 ILE B O 1 ATOM 3302 C CB . ILE B 1 41 ? -3.130 -37.866 -3.608 1.00 108.08 ? 37 ILE B CB 1 ATOM 3303 C CG1 . ILE B 1 41 ? -3.125 -38.898 -2.476 1.00 99.65 ? 37 ILE B CG1 1 ATOM 3304 C CG2 . ILE B 1 41 ? -3.199 -38.569 -4.968 1.00 105.31 ? 37 ILE B CG2 1 ATOM 3305 C CD1 . ILE B 1 41 ? -4.396 -39.723 -2.378 1.00 107.65 ? 37 ILE B CD1 1 ATOM 3306 N N . TRP B 1 42 ? -1.035 -36.340 -5.681 1.00 110.82 ? 38 TRP B N 1 ATOM 3307 C CA . TRP B 1 42 ? -0.968 -35.573 -6.912 1.00 106.33 ? 38 TRP B CA 1 ATOM 3308 C C . TRP B 1 42 ? -1.875 -36.225 -7.937 1.00 115.01 ? 38 TRP B C 1 ATOM 3309 O O . TRP B 1 42 ? -1.810 -37.436 -8.153 1.00 115.65 ? 38 TRP B O 1 ATOM 3310 C CB . TRP B 1 42 ? 0.469 -35.499 -7.423 1.00 105.54 ? 38 TRP B CB 1 ATOM 3311 C CG . TRP B 1 42 ? 1.394 -34.892 -6.422 1.00 115.28 ? 38 TRP B CG 1 ATOM 3312 C CD1 . TRP B 1 42 ? 1.946 -35.509 -5.339 1.00 117.70 ? 38 TRP B CD1 1 ATOM 3313 C CD2 . TRP B 1 42 ? 1.868 -33.541 -6.401 1.00 110.00 ? 38 TRP B CD2 1 ATOM 3314 N NE1 . TRP B 1 42 ? 2.737 -34.628 -4.645 1.00 119.26 ? 38 TRP B NE1 1 ATOM 3315 C CE2 . TRP B 1 42 ? 2.706 -33.412 -5.277 1.00 110.46 ? 38 TRP B CE2 1 ATOM 3316 C CE3 . TRP B 1 42 ? 1.667 -32.429 -7.223 1.00 101.19 ? 38 TRP B CE3 1 ATOM 3317 C CZ2 . TRP B 1 42 ? 3.343 -32.218 -4.955 1.00 105.96 ? 38 TRP B CZ2 1 ATOM 3318 C CZ3 . TRP B 1 42 ? 2.301 -31.246 -6.902 1.00 89.37 ? 38 TRP B CZ3 1 ATOM 3319 C CH2 . TRP B 1 42 ? 3.128 -31.149 -5.779 1.00 93.18 ? 38 TRP B CH2 1 ATOM 3320 N N . ILE B 1 43 ? -2.736 -35.421 -8.548 1.00 109.68 ? 39 ILE B N 1 ATOM 3321 C CA . ILE B 1 43 ? -3.680 -35.924 -9.531 1.00 104.24 ? 39 ILE B CA 1 ATOM 3322 C C . ILE B 1 43 ? -3.724 -35.020 -10.752 1.00 99.09 ? 39 ILE B C 1 ATOM 3323 O O . ILE B 1 43 ? -3.603 -33.800 -10.646 1.00 100.03 ? 39 ILE B O 1 ATOM 3324 C CB . ILE B 1 43 ? -5.104 -36.053 -8.935 1.00 109.24 ? 39 ILE B CB 1 ATOM 3325 C CG1 . ILE B 1 43 ? -5.606 -34.696 -8.424 1.00 105.94 ? 39 ILE B CG1 1 ATOM 3326 C CG2 . ILE B 1 43 ? -5.111 -37.088 -7.816 1.00 105.67 ? 39 ILE B CG2 1 ATOM 3327 C CD1 . ILE B 1 43 ? -7.037 -34.711 -7.908 1.00 107.97 ? 39 ILE B CD1 1 ATOM 3328 N N . ARG B 1 44 ? -3.882 -35.636 -11.917 1.00 102.92 ? 40 ARG B N 1 ATOM 3329 C CA . ARG B 1 44 ? -4.187 -34.900 -13.129 1.00 100.31 ? 40 ARG B CA 1 ATOM 3330 C C . ARG B 1 44 ? -5.590 -34.325 -12.933 1.00 105.50 ? 40 ARG B C 1 ATOM 3331 O O . ARG B 1 44 ? -6.320 -34.791 -12.059 1.00 114.29 ? 40 ARG B O 1 ATOM 3332 C CB . ARG B 1 44 ? -4.089 -35.811 -14.354 1.00 103.49 ? 40 ARG B CB 1 ATOM 3333 C CG . ARG B 1 44 ? -3.652 -35.109 -15.628 1.00 114.54 ? 40 ARG B CG 1 ATOM 3334 C CD . ARG B 1 44 ? -2.844 -36.048 -16.511 1.00 124.36 ? 40 ARG B CD 1 ATOM 3335 N NE . ARG B 1 44 ? -3.511 -37.331 -16.715 1.00 119.45 ? 40 ARG B NE 1 ATOM 3336 C CZ . ARG B 1 44 ? -4.445 -37.556 -17.634 1.00 120.03 ? 40 ARG B CZ 1 ATOM 3337 N NH1 . ARG B 1 44 ? -4.841 -36.583 -18.445 1.00 117.18 ? 40 ARG B NH1 1 ATOM 3338 N NH2 . ARG B 1 44 ? -4.990 -38.759 -17.741 1.00 118.22 ? 40 ARG B NH2 1 ATOM 3339 N N . SER B 1 45 ? -5.956 -33.307 -13.709 1.00 100.45 ? 41 SER B N 1 ATOM 3340 C CA . SER B 1 45 ? -7.174 -32.536 -13.440 1.00 104.47 ? 41 SER B CA 1 ATOM 3341 C C . SER B 1 45 ? -8.407 -33.418 -13.251 1.00 104.73 ? 41 SER B C 1 ATOM 3342 O O . SER B 1 45 ? -9.066 -33.348 -12.212 1.00 104.49 ? 41 SER B O 1 ATOM 3343 C CB . SER B 1 45 ? -7.428 -31.537 -14.568 1.00 104.28 ? 41 SER B CB 1 ATOM 3344 O OG . SER B 1 45 ? -7.693 -32.203 -15.789 1.00 91.83 ? 41 SER B OG 1 ATOM 3345 N N . ASP B 1 46 ? -8.717 -34.250 -14.240 1.00 104.37 ? 42 ASP B N 1 ATOM 3346 C CA . ASP B 1 46 ? -9.724 -35.286 -14.044 1.00 104.65 ? 42 ASP B CA 1 ATOM 3347 C C . ASP B 1 46 ? -9.137 -36.272 -13.041 1.00 115.63 ? 42 ASP B C 1 ATOM 3348 O O . ASP B 1 46 ? -7.974 -36.656 -13.148 1.00 116.85 ? 42 ASP B O 1 ATOM 3349 C CB . ASP B 1 46 ? -10.107 -35.965 -15.363 1.00 106.18 ? 42 ASP B CB 1 ATOM 3350 C CG . ASP B 1 46 ? -8.903 -36.427 -16.158 1.00 108.59 ? 42 ASP B CG 1 ATOM 3351 O OD1 . ASP B 1 46 ? -7.813 -35.847 -15.978 1.00 118.26 ? 42 ASP B OD1 1 ATOM 3352 O OD2 . ASP B 1 46 ? -9.052 -37.364 -16.969 1.00 116.95 ? 42 ASP B OD2 1 ATOM 3353 N N . GLY B 1 47 ? -9.957 -36.710 -12.093 1.00 125.06 ? 43 GLY B N 1 ATOM 3354 C CA . GLY B 1 47 ? -9.463 -37.167 -10.806 1.00 117.17 ? 43 GLY B CA 1 ATOM 3355 C C . GLY B 1 47 ? -8.586 -38.404 -10.785 1.00 116.84 ? 43 GLY B C 1 ATOM 3356 O O . GLY B 1 47 ? -8.180 -38.843 -9.709 1.00 128.27 ? 43 GLY B O 1 ATOM 3357 N N . THR B 1 48 ? -8.289 -38.973 -11.950 1.00 116.13 ? 44 THR B N 1 ATOM 3358 C CA . THR B 1 48 ? -7.397 -40.128 -12.007 1.00 111.27 ? 44 THR B CA 1 ATOM 3359 C C . THR B 1 48 ? -6.019 -39.752 -11.464 1.00 105.03 ? 44 THR B C 1 ATOM 3360 O O . THR B 1 48 ? -5.478 -38.693 -11.786 1.00 96.04 ? 44 THR B O 1 ATOM 3361 C CB . THR B 1 48 ? -7.256 -40.691 -13.444 1.00 99.80 ? 44 THR B CB 1 ATOM 3362 O OG1 . THR B 1 48 ? -6.486 -41.899 -13.409 1.00 98.29 ? 44 THR B OG1 1 ATOM 3363 C CG2 . THR B 1 48 ? -6.586 -39.686 -14.384 1.00 102.10 ? 44 THR B CG2 1 ATOM 3364 N N . ALA B 1 49 ? -5.466 -40.622 -10.623 1.00 105.21 ? 45 ALA B N 1 ATOM 3365 C CA . ALA B 1 49 ? -4.182 -40.367 -9.979 1.00 103.23 ? 45 ALA B CA 1 ATOM 3366 C C . ALA B 1 49 ? -3.027 -40.540 -10.959 1.00 102.55 ? 45 ALA B C 1 ATOM 3367 O O . ALA B 1 49 ? -3.174 -41.192 -11.994 1.00 98.83 ? 45 ALA B O 1 ATOM 3368 C CB . ALA B 1 49 ? -4.003 -41.287 -8.781 1.00 104.27 ? 45 ALA B CB 1 ATOM 3369 N N . VAL B 1 50 ? -1.882 -39.948 -10.625 1.00 103.57 ? 46 VAL B N 1 ATOM 3370 C CA . VAL B 1 50 ? -0.691 -40.032 -11.464 1.00 110.40 ? 46 VAL B CA 1 ATOM 3371 C C . VAL B 1 50 ? 0.486 -40.630 -10.700 1.00 97.95 ? 46 VAL B C 1 ATOM 3372 O O . VAL B 1 50 ? 0.752 -40.266 -9.554 1.00 96.89 ? 46 VAL B O 1 ATOM 3373 C CB . VAL B 1 50 ? -0.289 -38.646 -12.013 1.00 106.39 ? 46 VAL B CB 1 ATOM 3374 C CG1 . VAL B 1 50 ? -1.280 -38.199 -13.074 1.00 103.57 ? 46 VAL B CG1 1 ATOM 3375 C CG2 . VAL B 1 50 ? -0.198 -37.615 -10.890 1.00 101.95 ? 46 VAL B CG2 1 ATOM 3376 N N . GLY B 1 51 ? 1.172 -41.566 -11.349 1.00 103.42 ? 47 GLY B N 1 ATOM 3377 C CA . GLY B 1 51 ? 2.366 -42.178 -10.798 1.00 114.90 ? 47 GLY B CA 1 ATOM 3378 C C . GLY B 1 51 ? 3.603 -41.685 -11.520 1.00 111.95 ? 47 GLY B C 1 ATOM 3379 O O . GLY B 1 51 ? 3.566 -40.665 -12.207 1.00 96.68 ? 47 GLY B O 1 ATOM 3380 N N . ASP B 1 52 ? 4.700 -42.418 -11.368 1.00 116.15 ? 48 ASP B N 1 ATOM 3381 C CA . ASP B 1 52 ? 5.983 -42.003 -11.919 1.00 113.41 ? 48 ASP B CA 1 ATOM 3382 C C . ASP B 1 52 ? 6.178 -42.391 -13.383 1.00 116.89 ? 48 ASP B C 1 ATOM 3383 O O . ASP B 1 52 ? 5.709 -43.436 -13.835 1.00 117.57 ? 48 ASP B O 1 ATOM 3384 C CB . ASP B 1 52 ? 7.121 -42.602 -11.091 1.00 112.93 ? 48 ASP B CB 1 ATOM 3385 C CG . ASP B 1 52 ? 7.016 -42.257 -9.620 1.00 119.18 ? 48 ASP B CG 1 ATOM 3386 O OD1 . ASP B 1 52 ? 5.891 -41.980 -9.152 1.00 119.21 ? 48 ASP B OD1 1 ATOM 3387 O OD2 . ASP B 1 52 ? 8.058 -42.264 -8.932 1.00 121.51 ? 48 ASP B OD2 1 ATOM 3388 N N . VAL B 1 53 ? 6.863 -41.517 -14.113 1.00 107.32 ? 49 VAL B N 1 ATOM 3389 C CA . VAL B 1 53 ? 7.475 -41.858 -15.391 1.00 101.88 ? 49 VAL B CA 1 ATOM 3390 C C . VAL B 1 53 ? 8.949 -41.479 -15.249 1.00 106.05 ? 49 VAL B C 1 ATOM 3391 O O . VAL B 1 53 ? 9.366 -40.427 -15.734 1.00 109.41 ? 49 VAL B O 1 ATOM 3392 C CB . VAL B 1 53 ? 6.828 -41.118 -16.580 1.00 94.19 ? 49 VAL B CB 1 ATOM 3393 C CG1 . VAL B 1 53 ? 7.431 -41.601 -17.895 1.00 83.42 ? 49 VAL B CG1 1 ATOM 3394 C CG2 . VAL B 1 53 ? 5.324 -41.329 -16.576 1.00 107.24 ? 49 VAL B CG2 1 ATOM 3395 N N . PRO B 1 54 ? 9.738 -42.337 -14.572 1.00 108.25 ? 50 PRO B N 1 ATOM 3396 C CA . PRO B 1 54 ? 11.059 -41.961 -14.043 1.00 106.26 ? 50 PRO B CA 1 ATOM 3397 C C . PRO B 1 54 ? 11.974 -41.279 -15.057 1.00 101.03 ? 50 PRO B C 1 ATOM 3398 O O . PRO B 1 54 ? 12.050 -41.696 -16.214 1.00 97.97 ? 50 PRO B O 1 ATOM 3399 C CB . PRO B 1 54 ? 11.655 -43.304 -13.591 1.00 109.22 ? 50 PRO B CB 1 ATOM 3400 C CG . PRO B 1 54 ? 10.815 -44.358 -14.226 1.00 108.10 ? 50 PRO B CG 1 ATOM 3401 C CD . PRO B 1 54 ? 9.456 -43.766 -14.354 1.00 111.94 ? 50 PRO B CD 1 ATOM 3402 N N . GLY B 1 55 ? 12.655 -40.230 -14.601 1.00 100.19 ? 51 GLY B N 1 ATOM 3403 C CA . GLY B 1 55 ? 13.497 -39.407 -15.450 1.00 93.56 ? 51 GLY B CA 1 ATOM 3404 C C . GLY B 1 55 ? 12.809 -38.101 -15.805 1.00 93.71 ? 51 GLY B C 1 ATOM 3405 O O . GLY B 1 55 ? 13.466 -37.119 -16.153 1.00 95.78 ? 51 GLY B O 1 ATOM 3406 N N . LEU B 1 56 ? 11.481 -38.096 -15.709 1.00 102.06 ? 52 LEU B N 1 ATOM 3407 C CA . LEU B 1 56 ? 10.672 -36.916 -16.003 1.00 93.85 ? 52 LEU B CA 1 ATOM 3408 C C . LEU B 1 56 ? 9.688 -36.647 -14.878 1.00 94.47 ? 52 LEU B C 1 ATOM 3409 O O . LEU B 1 56 ? 9.743 -35.604 -14.229 1.00 101.86 ? 52 LEU B O 1 ATOM 3410 C CB . LEU B 1 56 ? 9.920 -37.095 -17.319 1.00 98.01 ? 52 LEU B CB 1 ATOM 3411 C CG . LEU B 1 56 ? 10.816 -37.321 -18.534 1.00 104.75 ? 52 LEU B CG 1 ATOM 3412 C CD1 . LEU B 1 56 ? 9.981 -37.710 -19.739 1.00 94.11 ? 52 LEU B CD1 1 ATOM 3413 C CD2 . LEU B 1 56 ? 11.644 -36.079 -18.826 1.00 95.38 ? 52 LEU B CD2 1 ATOM 3414 N N . ARG B 1 57 ? 8.768 -37.584 -14.674 1.00 87.85 ? 53 ARG B N 1 ATOM 3415 C CA . ARG B 1 57 ? 7.804 -37.485 -13.589 1.00 92.60 ? 53 ARG B CA 1 ATOM 3416 C C . ARG B 1 57 ? 8.062 -38.567 -12.555 1.00 99.96 ? 53 ARG B C 1 ATOM 3417 O O . ARG B 1 57 ? 7.930 -39.756 -12.837 1.00 109.89 ? 53 ARG B O 1 ATOM 3418 C CB . ARG B 1 57 ? 6.373 -37.603 -14.114 1.00 103.31 ? 53 ARG B CB 1 ATOM 3419 C CG . ARG B 1 57 ? 5.380 -36.709 -13.380 1.00 83.55 ? 53 ARG B CG 1 ATOM 3420 C CD . ARG B 1 57 ? 4.127 -37.448 -12.934 1.00 85.23 ? 53 ARG B CD 1 ATOM 3421 N NE . ARG B 1 57 ? 3.016 -37.254 -13.862 1.00 91.92 ? 53 ARG B NE 1 ATOM 3422 C CZ . ARG B 1 57 ? 2.779 -38.009 -14.931 1.00 102.24 ? 53 ARG B CZ 1 ATOM 3423 N NH1 . ARG B 1 57 ? 3.573 -39.028 -15.230 1.00 99.82 ? 53 ARG B NH1 1 ATOM 3424 N NH2 . ARG B 1 57 ? 1.739 -37.744 -15.708 1.00 107.99 ? 53 ARG B NH2 1 ATOM 3425 N N . GLN B 1 58 ? 8.461 -38.148 -11.362 1.00 89.67 ? 54 GLN B N 1 ATOM 3426 C CA . GLN B 1 58 ? 8.549 -39.053 -10.229 1.00 100.92 ? 54 GLN B CA 1 ATOM 3427 C C . GLN B 1 58 ? 8.312 -38.266 -8.955 1.00 92.29 ? 54 GLN B C 1 ATOM 3428 O O . GLN B 1 58 ? 8.730 -37.113 -8.842 1.00 94.93 ? 54 GLN B O 1 ATOM 3429 C CB . GLN B 1 58 ? 9.904 -39.759 -10.192 1.00 121.61 ? 54 GLN B CB 1 ATOM 3430 C CG . GLN B 1 58 ? 11.102 -38.825 -10.146 1.00 112.34 ? 54 GLN B CG 1 ATOM 3431 C CD . GLN B 1 58 ? 12.420 -39.567 -10.279 1.00 109.95 ? 54 GLN B CD 1 ATOM 3432 O OE1 . GLN B 1 58 ? 12.463 -40.702 -10.755 1.00 118.43 ? 54 GLN B OE1 1 ATOM 3433 N NE2 . GLN B 1 58 ? 13.504 -38.928 -9.855 1.00 112.51 ? 54 GLN B NE2 1 ATOM 3434 N N . ILE B 1 59 ? 7.649 -38.893 -7.991 1.00 97.92 ? 55 ILE B N 1 ATOM 3435 C CA . ILE B 1 59 ? 7.280 -38.202 -6.769 1.00 101.23 ? 55 ILE B CA 1 ATOM 3436 C C . ILE B 1 59 ? 8.383 -38.375 -5.740 1.00 115.38 ? 55 ILE B C 1 ATOM 3437 O O . ILE B 1 59 ? 8.630 -39.473 -5.241 1.00 121.45 ? 55 ILE B O 1 ATOM 3438 C CB . ILE B 1 59 ? 5.942 -38.719 -6.209 1.00 107.61 ? 55 ILE B CB 1 ATOM 3439 C CG1 . ILE B 1 59 ? 4.829 -38.472 -7.232 1.00 112.99 ? 55 ILE B CG1 1 ATOM 3440 C CG2 . ILE B 1 59 ? 5.614 -38.033 -4.882 1.00 108.64 ? 55 ILE B CG2 1 ATOM 3441 C CD1 . ILE B 1 59 ? 3.501 -39.099 -6.876 1.00 106.30 ? 55 ILE B CD1 1 ATOM 3442 N N . SER B 1 60 ? 9.044 -37.266 -5.438 1.00 121.70 ? 56 SER B N 1 ATOM 3443 C CA . SER B 1 60 ? 10.109 -37.239 -4.452 1.00 119.81 ? 56 SER B CA 1 ATOM 3444 C C . SER B 1 60 ? 9.520 -37.383 -3.059 1.00 123.80 ? 56 SER B C 1 ATOM 3445 O O . SER B 1 60 ? 8.317 -37.210 -2.861 1.00 121.91 ? 56 SER B O 1 ATOM 3446 C CB . SER B 1 60 ? 10.917 -35.944 -4.561 1.00 117.47 ? 56 SER B CB 1 ATOM 3447 O OG . SER B 1 60 ? 11.994 -35.932 -3.641 1.00 120.46 ? 56 SER B OG 1 ATOM 3448 N N . SER B 1 61 ? 10.375 -37.713 -2.099 1.00 131.32 ? 57 SER B N 1 ATOM 3449 C CA . SER B 1 61 ? 9.960 -37.842 -0.711 1.00 142.61 ? 57 SER B CA 1 ATOM 3450 C C . SER B 1 61 ? 9.416 -36.500 -0.229 1.00 139.06 ? 57 SER B C 1 ATOM 3451 O O . SER B 1 61 ? 9.717 -35.466 -0.825 1.00 136.41 ? 57 SER B O 1 ATOM 3452 C CB . SER B 1 61 ? 11.133 -38.299 0.156 1.00 138.25 ? 57 SER B CB 1 ATOM 3453 O OG . SER B 1 61 ? 11.785 -39.416 -0.422 1.00 109.38 ? 57 SER B OG 1 ATOM 3454 N N . ASP B 1 62 ? 8.608 -36.546 0.833 1.00 135.38 ? 58 ASP B N 1 ATOM 3455 C CA . ASP B 1 62 ? 7.789 -35.424 1.322 1.00 140.92 ? 58 ASP B CA 1 ATOM 3456 C C . ASP B 1 62 ? 6.459 -35.369 0.571 1.00 137.22 ? 58 ASP B C 1 ATOM 3457 O O . ASP B 1 62 ? 5.597 -34.546 0.882 1.00 141.33 ? 58 ASP B O 1 ATOM 3458 C CB . ASP B 1 62 ? 8.504 -34.068 1.198 1.00 143.50 ? 58 ASP B CB 1 ATOM 3459 C CG . ASP B 1 62 ? 9.917 -34.092 1.751 1.00 149.19 ? 58 ASP B CG 1 ATOM 3460 O OD1 . ASP B 1 62 ? 10.159 -34.820 2.736 1.00 153.65 ? 58 ASP B OD1 1 ATOM 3461 O OD2 . ASP B 1 62 ? 10.785 -33.379 1.202 1.00 140.77 ? 58 ASP B OD2 1 ATOM 3462 N N . GLY B 1 63 ? 6.291 -36.247 -0.414 1.00 136.69 ? 59 GLY B N 1 ATOM 3463 C CA . GLY B 1 63 ? 5.088 -36.252 -1.226 1.00 136.82 ? 59 GLY B CA 1 ATOM 3464 C C . GLY B 1 63 ? 5.075 -35.039 -2.134 1.00 135.91 ? 59 GLY B C 1 ATOM 3465 O O . GLY B 1 63 ? 4.030 -34.428 -2.363 1.00 126.24 ? 59 GLY B O 1 ATOM 3466 N N . LYS B 1 64 ? 6.255 -34.695 -2.645 1.00 130.74 ? 60 LYS B N 1 ATOM 3467 C CA . LYS B 1 64 ? 6.428 -33.535 -3.512 1.00 115.68 ? 60 LYS B CA 1 ATOM 3468 C C . LYS B 1 64 ? 6.857 -34.002 -4.897 1.00 111.57 ? 60 LYS B C 1 ATOM 3469 O O . LYS B 1 64 ? 7.517 -35.034 -5.031 1.00 122.53 ? 60 LYS B O 1 ATOM 3470 C CB . LYS B 1 64 ? 7.453 -32.568 -2.913 1.00 110.66 ? 60 LYS B CB 1 ATOM 3471 C CG . LYS B 1 64 ? 8.803 -32.539 -3.614 1.00 123.96 ? 60 LYS B CG 1 ATOM 3472 C CD . LYS B 1 64 ? 9.845 -31.851 -2.756 1.00 127.75 ? 60 LYS B CD 1 ATOM 3473 C CE . LYS B 1 64 ? 11.136 -31.641 -3.525 1.00 106.27 ? 60 LYS B CE 1 ATOM 3474 N NZ . LYS B 1 64 ? 12.288 -31.404 -2.616 1.00 102.88 ? 60 LYS B NZ 1 ATOM 3475 N N . LEU B 1 65 ? 6.486 -33.240 -5.922 1.00 103.40 ? 61 LEU B N 1 ATOM 3476 C CA . LEU B 1 65 ? 6.698 -33.659 -7.304 1.00 101.15 ? 61 LEU B CA 1 ATOM 3477 C C . LEU B 1 65 ? 7.799 -32.850 -7.987 1.00 100.78 ? 61 LEU B C 1 ATOM 3478 O O . LEU B 1 65 ? 7.749 -31.620 -8.036 1.00 95.78 ? 61 LEU B O 1 ATOM 3479 C CB . LEU B 1 65 ? 5.389 -33.545 -8.090 1.00 92.28 ? 61 LEU B CB 1 ATOM 3480 C CG . LEU B 1 65 ? 5.387 -34.031 -9.542 1.00 91.36 ? 61 LEU B CG 1 ATOM 3481 C CD1 . LEU B 1 65 ? 6.231 -35.287 -9.732 1.00 100.81 ? 61 LEU B CD1 1 ATOM 3482 C CD2 . LEU B 1 65 ? 3.957 -34.296 -9.982 1.00 102.22 ? 61 LEU B CD2 1 ATOM 3483 N N . VAL B 1 66 ? 8.789 -33.567 -8.513 1.00 106.48 ? 62 VAL B N 1 ATOM 3484 C CA . VAL B 1 66 ? 9.937 -32.969 -9.185 1.00 103.82 ? 62 VAL B CA 1 ATOM 3485 C C . VAL B 1 66 ? 9.915 -33.285 -10.680 1.00 101.17 ? 62 VAL B C 1 ATOM 3486 O O . VAL B 1 66 ? 9.422 -34.335 -11.094 1.00 93.73 ? 62 VAL B O 1 ATOM 3487 C CB . VAL B 1 66 ? 11.260 -33.476 -8.565 1.00 101.52 ? 62 VAL B CB 1 ATOM 3488 C CG1 . VAL B 1 66 ? 12.472 -32.919 -9.308 1.00 107.42 ? 62 VAL B CG1 1 ATOM 3489 C CG2 . VAL B 1 66 ? 11.320 -33.111 -7.086 1.00 104.57 ? 62 VAL B CG2 1 ATOM 3490 N N . PHE B 1 67 ? 10.447 -32.363 -11.479 1.00 103.75 ? 63 PHE B N 1 ATOM 3491 C CA . PHE B 1 67 ? 10.583 -32.554 -12.921 1.00 102.03 ? 63 PHE B CA 1 ATOM 3492 C C . PHE B 1 67 ? 12.047 -32.415 -13.330 1.00 99.92 ? 63 PHE B C 1 ATOM 3493 O O . PHE B 1 67 ? 12.488 -31.325 -13.697 1.00 96.46 ? 63 PHE B O 1 ATOM 3494 C CB . PHE B 1 67 ? 9.719 -31.547 -13.685 1.00 98.45 ? 63 PHE B CB 1 ATOM 3495 C CG . PHE B 1 67 ? 8.245 -31.741 -13.477 1.00 102.77 ? 63 PHE B CG 1 ATOM 3496 C CD1 . PHE B 1 67 ? 7.543 -32.670 -14.227 1.00 100.82 ? 63 PHE B CD1 1 ATOM 3497 C CD2 . PHE B 1 67 ? 7.562 -31.002 -12.528 1.00 99.62 ? 63 PHE B CD2 1 ATOM 3498 C CE1 . PHE B 1 67 ? 6.188 -32.855 -14.035 1.00 95.87 ? 63 PHE B CE1 1 ATOM 3499 C CE2 . PHE B 1 67 ? 6.207 -31.183 -12.331 1.00 97.07 ? 63 PHE B CE2 1 ATOM 3500 C CZ . PHE B 1 67 ? 5.519 -32.111 -13.086 1.00 91.39 ? 63 PHE B CZ 1 ATOM 3501 N N . PRO B 1 68 ? 12.812 -33.520 -13.258 1.00 97.07 ? 64 PRO B N 1 ATOM 3502 C CA . PRO B 1 68 ? 14.235 -33.462 -13.608 1.00 95.10 ? 64 PRO B CA 1 ATOM 3503 C C . PRO B 1 68 ? 14.464 -33.008 -15.049 1.00 91.59 ? 64 PRO B C 1 ATOM 3504 O O . PRO B 1 68 ? 13.610 -33.259 -15.900 1.00 88.99 ? 64 PRO B O 1 ATOM 3505 C CB . PRO B 1 68 ? 14.704 -34.908 -13.412 1.00 94.24 ? 64 PRO B CB 1 ATOM 3506 C CG . PRO B 1 68 ? 13.718 -35.508 -12.464 1.00 96.36 ? 64 PRO B CG 1 ATOM 3507 C CD . PRO B 1 68 ? 12.416 -34.869 -12.817 1.00 93.52 ? 64 PRO B CD 1 ATOM 3508 N N . PRO B 1 69 ? 15.599 -32.340 -15.321 1.00 90.08 ? 65 PRO B N 1 ATOM 3509 C CA . PRO B 1 69 ? 15.921 -31.950 -16.698 1.00 87.62 ? 65 PRO B CA 1 ATOM 3510 C C . PRO B 1 69 ? 16.073 -33.170 -17.598 1.00 79.31 ? 65 PRO B C 1 ATOM 3511 O O . PRO B 1 69 ? 16.372 -34.259 -17.107 1.00 92.53 ? 65 PRO B O 1 ATOM 3512 C CB . PRO B 1 69 ? 17.243 -31.189 -16.555 1.00 89.10 ? 65 PRO B CB 1 ATOM 3513 C CG . PRO B 1 69 ? 17.817 -31.646 -15.252 1.00 92.26 ? 65 PRO B CG 1 ATOM 3514 C CD . PRO B 1 69 ? 16.643 -31.921 -14.371 1.00 87.14 ? 65 PRO B CD 1 ATOM 3515 N N . PHE B 1 70 ? 15.871 -32.982 -18.897 1.00 76.71 ? 66 PHE B N 1 ATOM 3516 C CA . PHE B 1 70 ? 15.801 -34.094 -19.834 1.00 90.17 ? 66 PHE B CA 1 ATOM 3517 C C . PHE B 1 70 ? 16.273 -33.669 -21.215 1.00 96.28 ? 66 PHE B C 1 ATOM 3518 O O . PHE B 1 70 ? 16.307 -32.479 -21.527 1.00 89.83 ? 66 PHE B O 1 ATOM 3519 C CB . PHE B 1 70 ? 14.368 -34.625 -19.908 1.00 98.84 ? 66 PHE B CB 1 ATOM 3520 C CG . PHE B 1 70 ? 13.343 -33.558 -20.208 1.00 106.63 ? 66 PHE B CG 1 ATOM 3521 C CD1 . PHE B 1 70 ? 12.923 -32.682 -19.220 1.00 97.84 ? 66 PHE B CD1 1 ATOM 3522 C CD2 . PHE B 1 70 ? 12.802 -33.431 -21.476 1.00 101.79 ? 66 PHE B CD2 1 ATOM 3523 C CE1 . PHE B 1 70 ? 11.989 -31.700 -19.494 1.00 79.01 ? 66 PHE B CE1 1 ATOM 3524 C CE2 . PHE B 1 70 ? 11.865 -32.451 -21.752 1.00 85.02 ? 66 PHE B CE2 1 ATOM 3525 C CZ . PHE B 1 70 ? 11.461 -31.586 -20.760 1.00 73.06 ? 66 PHE B CZ 1 ATOM 3526 N N . ARG B 1 71 ? 16.640 -34.644 -22.039 1.00 102.38 ? 67 ARG B N 1 ATOM 3527 C CA . ARG B 1 71 ? 17.038 -34.360 -23.410 1.00 101.85 ? 67 ARG B CA 1 ATOM 3528 C C . ARG B 1 71 ? 15.780 -34.085 -24.231 1.00 100.92 ? 67 ARG B C 1 ATOM 3529 O O . ARG B 1 71 ? 14.668 -34.229 -23.729 1.00 93.79 ? 67 ARG B O 1 ATOM 3530 C CB . ARG B 1 71 ? 17.844 -35.534 -23.984 1.00 94.76 ? 67 ARG B CB 1 ATOM 3531 C CG . ARG B 1 71 ? 18.699 -35.218 -25.212 1.00 105.79 ? 67 ARG B CG 1 ATOM 3532 C CD . ARG B 1 71 ? 19.669 -34.075 -24.954 1.00 109.76 ? 67 ARG B CD 1 ATOM 3533 N NE . ARG B 1 71 ? 20.518 -33.781 -26.104 1.00 113.57 ? 67 ARG B NE 1 ATOM 3534 C CZ . ARG B 1 71 ? 20.134 -33.061 -27.152 1.00 100.94 ? 67 ARG B CZ 1 ATOM 3535 N NH1 . ARG B 1 71 ? 18.905 -32.568 -27.214 1.00 93.20 ? 67 ARG B NH1 1 ATOM 3536 N NH2 . ARG B 1 71 ? 20.978 -32.841 -28.148 1.00 109.38 ? 67 ARG B NH2 1 ATOM 3537 N N . ALA B 1 72 ? 15.948 -33.707 -25.493 1.00 101.65 ? 68 ALA B N 1 ATOM 3538 C CA . ALA B 1 72 ? 14.816 -33.306 -26.322 1.00 96.93 ? 68 ALA B CA 1 ATOM 3539 C C . ALA B 1 72 ? 14.020 -34.505 -26.830 1.00 104.24 ? 68 ALA B C 1 ATOM 3540 O O . ALA B 1 72 ? 12.790 -34.466 -26.877 1.00 105.36 ? 68 ALA B O 1 ATOM 3541 C CB . ALA B 1 72 ? 15.302 -32.466 -27.493 1.00 94.18 ? 68 ALA B CB 1 ATOM 3542 N N . GLU B 1 73 ? 14.724 -35.569 -27.201 1.00 110.00 ? 69 GLU B N 1 ATOM 3543 C CA . GLU B 1 73 ? 14.096 -36.726 -27.835 1.00 103.38 ? 69 GLU B CA 1 ATOM 3544 C C . GLU B 1 73 ? 13.187 -37.493 -26.877 1.00 96.25 ? 69 GLU B C 1 ATOM 3545 O O . GLU B 1 73 ? 12.163 -38.044 -27.287 1.00 83.68 ? 69 GLU B O 1 ATOM 3546 C CB . GLU B 1 73 ? 15.164 -37.671 -28.397 1.00 105.34 ? 69 GLU B CB 1 ATOM 3547 C CG . GLU B 1 73 ? 15.994 -37.077 -29.531 1.00 100.21 ? 69 GLU B CG 1 ATOM 3548 C CD . GLU B 1 73 ? 17.081 -36.137 -29.046 1.00 104.60 ? 69 GLU B CD 1 ATOM 3549 O OE1 . GLU B 1 73 ? 17.676 -36.404 -27.981 1.00 103.85 ? 69 GLU B OE1 1 ATOM 3550 O OE2 . GLU B 1 73 ? 17.340 -35.126 -29.734 1.00 109.88 ? 69 GLU B OE2 1 ATOM 3551 N N . ASP B 1 74 ? 13.562 -37.523 -25.602 1.00 102.52 ? 70 ASP B N 1 ATOM 3552 C CA . ASP B 1 74 ? 12.813 -38.270 -24.596 1.00 106.35 ? 70 ASP B CA 1 ATOM 3553 C C . ASP B 1 74 ? 11.469 -37.612 -24.283 1.00 105.40 ? 70 ASP B C 1 ATOM 3554 O O . ASP B 1 74 ? 10.643 -38.180 -23.568 1.00 110.54 ? 70 ASP B O 1 ATOM 3555 C CB . ASP B 1 74 ? 13.639 -38.400 -23.314 1.00 106.40 ? 70 ASP B CB 1 ATOM 3556 C CG . ASP B 1 74 ? 14.893 -39.228 -23.510 1.00 101.70 ? 70 ASP B CG 1 ATOM 3557 O OD1 . ASP B 1 74 ? 15.872 -38.704 -24.082 1.00 105.14 ? 70 ASP B OD1 1 ATOM 3558 O OD2 . ASP B 1 74 ? 14.902 -40.403 -23.087 1.00 92.21 ? 70 ASP B OD2 1 ATOM 3559 N N . TYR B 1 75 ? 11.260 -36.416 -24.826 1.00 104.05 ? 71 TYR B N 1 ATOM 3560 C CA . TYR B 1 75 ? 10.044 -35.647 -24.583 1.00 103.75 ? 71 TYR B CA 1 ATOM 3561 C C . TYR B 1 75 ? 8.777 -36.394 -24.992 1.00 102.35 ? 71 TYR B C 1 ATOM 3562 O O . TYR B 1 75 ? 8.671 -36.891 -26.113 1.00 112.14 ? 71 TYR B O 1 ATOM 3563 C CB . TYR B 1 75 ? 10.119 -34.312 -25.330 1.00 101.55 ? 71 TYR B CB 1 ATOM 3564 C CG . TYR B 1 75 ? 8.834 -33.512 -25.308 1.00 109.07 ? 71 TYR B CG 1 ATOM 3565 C CD1 . TYR B 1 75 ? 8.551 -32.642 -24.264 1.00 107.34 ? 71 TYR B CD1 1 ATOM 3566 C CD2 . TYR B 1 75 ? 7.907 -33.621 -26.337 1.00 108.93 ? 71 TYR B CD2 1 ATOM 3567 C CE1 . TYR B 1 75 ? 7.380 -31.908 -24.242 1.00 98.74 ? 71 TYR B CE1 1 ATOM 3568 C CE2 . TYR B 1 75 ? 6.733 -32.892 -26.322 1.00 102.43 ? 71 TYR B CE2 1 ATOM 3569 C CZ . TYR B 1 75 ? 6.475 -32.037 -25.274 1.00 96.30 ? 71 TYR B CZ 1 ATOM 3570 O OH . TYR B 1 75 ? 5.307 -31.309 -25.258 1.00 96.16 ? 71 TYR B OH 1 ATOM 3571 N N . ARG B 1 76 ? 7.826 -36.468 -24.066 1.00 99.78 ? 72 ARG B N 1 ATOM 3572 C CA . ARG B 1 76 ? 6.491 -36.987 -24.347 1.00 110.39 ? 72 ARG B CA 1 ATOM 3573 C C . ARG B 1 76 ? 5.473 -36.058 -23.688 1.00 105.20 ? 72 ARG B C 1 ATOM 3574 O O . ARG B 1 76 ? 5.708 -35.548 -22.593 1.00 101.59 ? 72 ARG B O 1 ATOM 3575 C CB . ARG B 1 76 ? 6.340 -38.426 -23.845 1.00 113.27 ? 72 ARG B CB 1 ATOM 3576 C CG . ARG B 1 76 ? 7.361 -39.399 -24.432 1.00 102.27 ? 72 ARG B CG 1 ATOM 3577 C CD . ARG B 1 76 ? 7.155 -39.612 -25.930 1.00 101.76 ? 72 ARG B CD 1 ATOM 3578 N NE . ARG B 1 76 ? 8.323 -40.216 -26.569 1.00 112.71 ? 72 ARG B NE 1 ATOM 3579 C CZ . ARG B 1 76 ? 8.457 -40.388 -27.881 1.00 108.28 ? 72 ARG B CZ 1 ATOM 3580 N NH1 . ARG B 1 76 ? 7.497 -40.002 -28.710 1.00 103.38 ? 72 ARG B NH1 1 ATOM 3581 N NH2 . ARG B 1 76 ? 9.557 -40.946 -28.366 1.00 110.30 ? 72 ARG B NH2 1 ATOM 3582 N N . GLN B 1 77 ? 4.351 -35.834 -24.364 1.00 100.60 ? 73 GLN B N 1 ATOM 3583 C CA . GLN B 1 77 ? 3.416 -34.779 -23.977 1.00 93.10 ? 73 GLN B CA 1 ATOM 3584 C C . GLN B 1 77 ? 2.782 -34.962 -22.601 1.00 90.89 ? 73 GLN B C 1 ATOM 3585 O O . GLN B 1 77 ? 2.806 -34.040 -21.785 1.00 98.09 ? 73 GLN B O 1 ATOM 3586 C CB . GLN B 1 77 ? 2.298 -34.664 -25.015 1.00 96.47 ? 73 GLN B CB 1 ATOM 3587 C CG . GLN B 1 77 ? 1.249 -33.605 -24.683 1.00 89.55 ? 73 GLN B CG 1 ATOM 3588 C CD . GLN B 1 77 ? 0.016 -33.718 -25.547 1.00 94.51 ? 73 GLN B CD 1 ATOM 3589 O OE1 . GLN B 1 77 ? 0.076 -33.552 -26.766 1.00 88.55 ? 73 GLN B OE1 1 ATOM 3590 N NE2 . GLN B 1 77 ? -1.116 -34.013 -24.918 1.00 90.28 ? 73 GLN B NE2 1 ATOM 3591 N N . GLU B 1 78 ? 2.204 -36.137 -22.359 1.00 88.14 ? 74 GLU B N 1 ATOM 3592 C CA . GLU B 1 78 ? 1.333 -36.348 -21.201 1.00 90.61 ? 74 GLU B CA 1 ATOM 3593 C C . GLU B 1 78 ? 1.959 -35.864 -19.900 1.00 88.67 ? 74 GLU B C 1 ATOM 3594 O O . GLU B 1 78 ? 1.265 -35.350 -19.022 1.00 92.38 ? 74 GLU B O 1 ATOM 3595 C CB . GLU B 1 78 ? 0.970 -37.828 -21.061 1.00 101.12 ? 74 GLU B CB 1 ATOM 3596 C CG . GLU B 1 78 ? -0.127 -38.293 -22.007 1.00 112.82 ? 74 GLU B CG 1 ATOM 3597 C CD . GLU B 1 78 ? -0.706 -39.643 -21.622 1.00 107.01 ? 74 GLU B CD 1 ATOM 3598 O OE1 . GLU B 1 78 ? -0.386 -40.147 -20.524 1.00 101.47 ? 74 GLU B OE1 1 ATOM 3599 O OE2 . GLU B 1 78 ? -1.488 -40.202 -22.421 1.00 97.96 ? 74 GLU B OE2 1 ATOM 3600 N N . VAL B 1 79 ? 3.273 -36.028 -19.786 1.00 97.68 ? 75 VAL B N 1 ATOM 3601 C CA . VAL B 1 79 ? 3.994 -35.597 -18.593 1.00 99.71 ? 75 VAL B CA 1 ATOM 3602 C C . VAL B 1 79 ? 4.310 -34.099 -18.597 1.00 93.09 ? 75 VAL B C 1 ATOM 3603 O O . VAL B 1 79 ? 4.151 -33.429 -17.577 1.00 88.87 ? 75 VAL B O 1 ATOM 3604 C CB . VAL B 1 79 ? 5.317 -36.386 -18.412 1.00 89.42 ? 75 VAL B CB 1 ATOM 3605 C CG1 . VAL B 1 79 ? 6.189 -36.313 -19.663 1.00 91.62 ? 75 VAL B CG1 1 ATOM 3606 C CG2 . VAL B 1 79 ? 6.076 -35.880 -17.188 1.00 91.52 ? 75 VAL B CG2 1 ATOM 3607 N N . HIS B 1 80 ? 4.746 -33.576 -19.740 1.00 93.53 ? 76 HIS B N 1 ATOM 3608 C CA . HIS B 1 80 ? 5.277 -32.214 -19.799 1.00 96.20 ? 76 HIS B CA 1 ATOM 3609 C C . HIS B 1 80 ? 4.175 -31.170 -19.916 1.00 95.70 ? 76 HIS B C 1 ATOM 3610 O O . HIS B 1 80 ? 3.874 -30.470 -18.948 1.00 95.42 ? 76 HIS B O 1 ATOM 3611 C CB . HIS B 1 80 ? 6.244 -32.074 -20.975 1.00 99.17 ? 76 HIS B CB 1 ATOM 3612 C CG . HIS B 1 80 ? 7.464 -32.931 -20.856 1.00 98.01 ? 76 HIS B CG 1 ATOM 3613 N ND1 . HIS B 1 80 ? 7.661 -34.057 -21.627 1.00 107.42 ? 76 HIS B ND1 1 ATOM 3614 C CD2 . HIS B 1 80 ? 8.547 -32.833 -20.050 1.00 88.18 ? 76 HIS B CD2 1 ATOM 3615 C CE1 . HIS B 1 80 ? 8.815 -34.612 -21.304 1.00 99.86 ? 76 HIS B CE1 1 ATOM 3616 N NE2 . HIS B 1 80 ? 9.373 -33.889 -20.350 1.00 92.10 ? 76 HIS B NE2 1 ATOM 3617 N N . ALA B 1 81 ? 3.572 -31.070 -21.097 1.00 93.50 ? 77 ALA B N 1 ATOM 3618 C CA . ALA B 1 81 ? 2.450 -30.164 -21.288 1.00 95.84 ? 77 ALA B CA 1 ATOM 3619 C C . ALA B 1 81 ? 1.203 -30.857 -20.767 1.00 90.60 ? 77 ALA B C 1 ATOM 3620 O O . ALA B 1 81 ? 0.774 -31.872 -21.316 1.00 95.32 ? 77 ALA B O 1 ATOM 3621 C CB . ALA B 1 81 ? 2.296 -29.788 -22.754 1.00 88.70 ? 77 ALA B CB 1 ATOM 3622 N N . GLN B 1 82 ? 0.606 -30.286 -19.726 1.00 82.95 ? 78 GLN B N 1 ATOM 3623 C CA . GLN B 1 82 ? -0.459 -30.958 -18.993 1.00 87.76 ? 78 GLN B CA 1 ATOM 3624 C C . GLN B 1 82 ? -0.955 -30.076 -17.854 1.00 88.18 ? 78 GLN B C 1 ATOM 3625 O O . GLN B 1 82 ? -0.309 -29.092 -17.489 1.00 81.39 ? 78 GLN B O 1 ATOM 3626 C CB . GLN B 1 82 ? 0.034 -32.306 -18.443 1.00 87.89 ? 78 GLN B CB 1 ATOM 3627 C CG . GLN B 1 82 ? -1.034 -33.160 -17.771 1.00 94.13 ? 78 GLN B CG 1 ATOM 3628 C CD . GLN B 1 82 ? -2.231 -33.413 -18.666 1.00 93.73 ? 78 GLN B CD 1 ATOM 3629 O OE1 . GLN B 1 82 ? -3.376 -33.201 -18.266 1.00 103.96 ? 78 GLN B OE1 1 ATOM 3630 N NE2 . GLN B 1 82 ? -1.974 -33.881 -19.881 1.00 98.70 ? 78 GLN B NE2 1 ATOM 3631 N N . VAL B 1 83 ? -2.112 -30.436 -17.307 1.00 90.94 ? 79 VAL B N 1 ATOM 3632 C CA . VAL B 1 83 ? -2.674 -29.766 -16.141 1.00 79.20 ? 79 VAL B CA 1 ATOM 3633 C C . VAL B 1 83 ? -2.735 -30.743 -14.973 1.00 81.42 ? 79 VAL B C 1 ATOM 3634 O O . VAL B 1 83 ? -3.453 -31.742 -15.025 1.00 90.22 ? 79 VAL B O 1 ATOM 3635 C CB . VAL B 1 83 ? -4.078 -29.213 -16.437 1.00 80.47 ? 79 VAL B CB 1 ATOM 3636 C CG1 . VAL B 1 83 ? -4.667 -28.538 -15.199 1.00 84.02 ? 79 VAL B CG1 1 ATOM 3637 C CG2 . VAL B 1 83 ? -4.015 -28.246 -17.614 1.00 85.12 ? 79 VAL B CG2 1 ATOM 3638 N N . TYR B 1 84 ? -1.973 -30.447 -13.925 1.00 85.91 ? 80 TYR B N 1 ATOM 3639 C CA . TYR B 1 84 ? -1.921 -31.295 -12.740 1.00 81.46 ? 80 TYR B CA 1 ATOM 3640 C C . TYR B 1 84 ? -2.737 -30.697 -11.607 1.00 84.46 ? 80 TYR B C 1 ATOM 3641 O O . TYR B 1 84 ? -3.398 -29.675 -11.777 1.00 78.41 ? 80 TYR B O 1 ATOM 3642 C CB . TYR B 1 84 ? -0.473 -31.502 -12.292 1.00 74.36 ? 80 TYR B CB 1 ATOM 3643 C CG . TYR B 1 84 ? 0.333 -32.335 -13.253 1.00 83.58 ? 80 TYR B CG 1 ATOM 3644 C CD1 . TYR B 1 84 ? 1.112 -31.741 -14.233 1.00 79.32 ? 80 TYR B CD1 1 ATOM 3645 C CD2 . TYR B 1 84 ? 0.305 -33.720 -13.188 1.00 99.14 ? 80 TYR B CD2 1 ATOM 3646 C CE1 . TYR B 1 84 ? 1.847 -32.502 -15.117 1.00 85.43 ? 80 TYR B CE1 1 ATOM 3647 C CE2 . TYR B 1 84 ? 1.035 -34.488 -14.067 1.00 99.04 ? 80 TYR B CE2 1 ATOM 3648 C CZ . TYR B 1 84 ? 1.804 -33.876 -15.029 1.00 94.01 ? 80 TYR B CZ 1 ATOM 3649 O OH . TYR B 1 84 ? 2.532 -34.642 -15.904 1.00 94.93 ? 80 TYR B OH 1 ATOM 3650 N N . ALA B 1 85 ? -2.695 -31.355 -10.455 1.00 90.97 ? 81 ALA B N 1 ATOM 3651 C CA . ALA B 1 85 ? -3.366 -30.863 -9.264 1.00 89.76 ? 81 ALA B CA 1 ATOM 3652 C C . ALA B 1 85 ? -2.824 -31.577 -8.032 1.00 95.08 ? 81 ALA B C 1 ATOM 3653 O O . ALA B 1 85 ? -1.897 -32.382 -8.124 1.00 99.23 ? 81 ALA B O 1 ATOM 3654 C CB . ALA B 1 85 ? -4.876 -31.052 -9.381 1.00 102.05 ? 81 ALA B CB 1 ATOM 3655 N N . CYS B 1 86 ? -3.411 -31.271 -6.882 1.00 101.65 ? 82 CYS B N 1 ATOM 3656 C CA . CYS B 1 86 ? -2.972 -31.826 -5.609 1.00 102.80 ? 82 CYS B CA 1 ATOM 3657 C C . CYS B 1 86 ? -4.174 -31.932 -4.683 1.00 98.35 ? 82 CYS B C 1 ATOM 3658 O O . CYS B 1 86 ? -5.122 -31.155 -4.803 1.00 93.99 ? 82 CYS B O 1 ATOM 3659 C CB . CYS B 1 86 ? -1.879 -30.955 -4.986 1.00 105.11 ? 82 CYS B CB 1 ATOM 3660 S SG . CYS B 1 86 ? -1.369 -31.456 -3.323 1.00 127.67 ? 82 CYS B SG 1 ATOM 3661 N N . LEU B 1 87 ? -4.140 -32.894 -3.768 1.00 103.87 ? 83 LEU B N 1 ATOM 3662 C CA . LEU B 1 87 ? -5.283 -33.139 -2.900 1.00 100.32 ? 83 LEU B CA 1 ATOM 3663 C C . LEU B 1 87 ? -4.863 -33.686 -1.537 1.00 116.29 ? 83 LEU B C 1 ATOM 3664 O O . LEU B 1 87 ? -3.921 -34.471 -1.434 1.00 125.46 ? 83 LEU B O 1 ATOM 3665 C CB . LEU B 1 87 ? -6.253 -34.098 -3.594 1.00 95.45 ? 83 LEU B CB 1 ATOM 3666 C CG . LEU B 1 87 ? -7.593 -34.359 -2.910 1.00 100.65 ? 83 LEU B CG 1 ATOM 3667 C CD1 . LEU B 1 87 ? -8.705 -34.432 -3.942 1.00 108.13 ? 83 LEU B CD1 1 ATOM 3668 C CD2 . LEU B 1 87 ? -7.517 -35.633 -2.116 1.00 97.63 ? 83 LEU B CD2 1 ATOM 3669 N N . ALA B 1 88 ? -5.578 -33.257 -0.498 1.00 104.50 ? 84 ALA B N 1 ATOM 3670 C CA . ALA B 1 88 ? -5.299 -33.660 0.879 1.00 109.67 ? 84 ALA B CA 1 ATOM 3671 C C . ALA B 1 88 ? -6.509 -34.382 1.461 1.00 107.60 ? 84 ALA B C 1 ATOM 3672 O O . ALA B 1 88 ? -7.644 -34.024 1.152 1.00 110.07 ? 84 ALA B O 1 ATOM 3673 C CB . ALA B 1 88 ? -4.942 -32.449 1.725 1.00 106.85 ? 84 ALA B CB 1 ATOM 3674 N N . ARG B 1 89 ? -6.273 -35.390 2.301 1.00 110.05 ? 85 ARG B N 1 ATOM 3675 C CA . ARG B 1 89 ? -7.369 -36.197 2.835 1.00 109.23 ? 85 ARG B CA 1 ATOM 3676 C C . ARG B 1 89 ? -7.205 -36.616 4.287 1.00 112.15 ? 85 ARG B C 1 ATOM 3677 O O . ARG B 1 89 ? -6.137 -37.047 4.722 1.00 108.49 ? 85 ARG B O 1 ATOM 3678 C CB . ARG B 1 89 ? -7.552 -37.455 1.990 1.00 111.11 ? 85 ARG B CB 1 ATOM 3679 C CG . ARG B 1 89 ? -7.751 -37.162 0.535 1.00 109.67 ? 85 ARG B CG 1 ATOM 3680 C CD . ARG B 1 89 ? -8.211 -38.384 -0.227 1.00 102.38 ? 85 ARG B CD 1 ATOM 3681 N NE . ARG B 1 89 ? -7.244 -39.471 -0.128 1.00 94.81 ? 85 ARG B NE 1 ATOM 3682 C CZ . ARG B 1 89 ? -7.382 -40.650 -0.724 1.00 105.83 ? 85 ARG B CZ 1 ATOM 3683 N NH1 . ARG B 1 89 ? -8.451 -40.901 -1.466 1.00 90.64 ? 85 ARG B NH1 1 ATOM 3684 N NH2 . ARG B 1 89 ? -6.449 -41.580 -0.577 1.00 108.53 ? 85 ARG B NH2 1 ATOM 3685 N N . ASN B 1 90 ? -8.301 -36.473 5.021 1.00 113.98 ? 86 ASN B N 1 ATOM 3686 C CA . ASN B 1 90 ? -8.477 -37.091 6.322 1.00 117.91 ? 86 ASN B CA 1 ATOM 3687 C C . ASN B 1 90 ? -9.816 -37.811 6.291 1.00 120.07 ? 86 ASN B C 1 ATOM 3688 O O . ASN B 1 90 ? -10.443 -37.912 5.235 1.00 119.28 ? 86 ASN B O 1 ATOM 3689 C CB . ASN B 1 90 ? -8.442 -36.055 7.447 1.00 119.71 ? 86 ASN B CB 1 ATOM 3690 C CG . ASN B 1 90 ? -7.264 -35.107 7.336 1.00 115.84 ? 86 ASN B CG 1 ATOM 3691 O OD1 . ASN B 1 90 ? -7.400 -33.906 7.567 1.00 114.83 ? 86 ASN B OD1 1 ATOM 3692 N ND2 . ASN B 1 90 ? -6.102 -35.641 6.982 1.00 114.60 ? 86 ASN B ND2 1 ATOM 3693 N N . GLN B 1 91 ? -10.258 -38.318 7.435 1.00 124.73 ? 87 GLN B N 1 ATOM 3694 C CA . GLN B 1 91 ? -11.626 -38.809 7.552 1.00 121.17 ? 87 GLN B CA 1 ATOM 3695 C C . GLN B 1 91 ? -12.612 -37.660 7.315 1.00 121.53 ? 87 GLN B C 1 ATOM 3696 O O . GLN B 1 91 ? -13.801 -37.886 7.085 1.00 128.58 ? 87 GLN B O 1 ATOM 3697 C CB . GLN B 1 91 ? -11.866 -39.447 8.924 1.00 120.02 ? 87 GLN B CB 1 ATOM 3698 C CG . GLN B 1 91 ? -11.564 -38.538 10.115 1.00 120.28 ? 87 GLN B CG 1 ATOM 3699 C CD . GLN B 1 91 ? -10.108 -38.574 10.554 1.00 121.08 ? 87 GLN B CD 1 ATOM 3700 O OE1 . GLN B 1 91 ? -9.293 -39.309 9.995 1.00 123.64 ? 87 GLN B OE1 1 ATOM 3701 N NE2 . GLN B 1 91 ? -9.776 -37.773 11.560 1.00 115.44 ? 87 GLN B NE2 1 ATOM 3702 N N . PHE B 1 92 ? -12.103 -36.431 7.373 1.00 119.21 ? 88 PHE B N 1 ATOM 3703 C CA . PHE B 1 92 ? -12.906 -35.233 7.143 1.00 116.61 ? 88 PHE B CA 1 ATOM 3704 C C . PHE B 1 92 ? -13.211 -34.992 5.665 1.00 119.71 ? 88 PHE B C 1 ATOM 3705 O O . PHE B 1 92 ? -14.032 -34.139 5.336 1.00 128.19 ? 88 PHE B O 1 ATOM 3706 C CB . PHE B 1 92 ? -12.194 -34.007 7.719 1.00 118.69 ? 88 PHE B CB 1 ATOM 3707 C CG . PHE B 1 92 ? -12.252 -33.922 9.217 1.00 120.10 ? 88 PHE B CG 1 ATOM 3708 C CD1 . PHE B 1 92 ? -11.580 -34.841 10.004 1.00 114.92 ? 88 PHE B CD1 1 ATOM 3709 C CD2 . PHE B 1 92 ? -12.978 -32.921 9.839 1.00 118.70 ? 88 PHE B CD2 1 ATOM 3710 C CE1 . PHE B 1 92 ? -11.635 -34.765 11.381 1.00 110.16 ? 88 PHE B CE1 1 ATOM 3711 C CE2 . PHE B 1 92 ? -13.034 -32.839 11.215 1.00 112.52 ? 88 PHE B CE2 1 ATOM 3712 C CZ . PHE B 1 92 ? -12.362 -33.762 11.987 1.00 105.73 ? 88 PHE B CZ 1 ATOM 3713 N N . GLY B 1 93 ? -12.558 -35.743 4.782 1.00 120.88 ? 89 GLY B N 1 ATOM 3714 C CA . GLY B 1 93 ? -12.778 -35.604 3.352 1.00 125.80 ? 89 GLY B CA 1 ATOM 3715 C C . GLY B 1 93 ? -11.663 -34.891 2.608 1.00 113.44 ? 89 GLY B C 1 ATOM 3716 O O . GLY B 1 93 ? -10.580 -34.669 3.150 1.00 108.17 ? 89 GLY B O 1 ATOM 3717 N N . SER B 1 94 ? -11.947 -34.524 1.360 1.00 111.79 ? 90 SER B N 1 ATOM 3718 C CA . SER B 1 94 ? -10.920 -34.115 0.408 1.00 103.92 ? 90 SER B CA 1 ATOM 3719 C C . SER B 1 94 ? -11.039 -32.660 -0.042 1.00 97.26 ? 90 SER B C 1 ATOM 3720 O O . SER B 1 94 ? -12.109 -32.058 0.034 1.00 103.81 ? 90 SER B O 1 ATOM 3721 C CB . SER B 1 94 ? -10.975 -35.023 -0.821 1.00 103.47 ? 90 SER B CB 1 ATOM 3722 O OG . SER B 1 94 ? -10.781 -36.380 -0.465 1.00 106.66 ? 90 SER B OG 1 ATOM 3723 N N . ILE B 1 95 ? -9.920 -32.109 -0.506 1.00 100.44 ? 91 ILE B N 1 ATOM 3724 C CA . ILE B 1 95 ? -9.880 -30.760 -1.064 1.00 103.89 ? 91 ILE B CA 1 ATOM 3725 C C . ILE B 1 95 ? -8.901 -30.694 -2.236 1.00 103.06 ? 91 ILE B C 1 ATOM 3726 O O . ILE B 1 95 ? -7.788 -31.203 -2.150 1.00 105.44 ? 91 ILE B O 1 ATOM 3727 C CB . ILE B 1 95 ? -9.476 -29.723 -0.004 1.00 115.87 ? 91 ILE B CB 1 ATOM 3728 C CG1 . ILE B 1 95 ? -8.344 -30.268 0.869 1.00 109.89 ? 91 ILE B CG1 1 ATOM 3729 C CG2 . ILE B 1 95 ? -10.679 -29.354 0.851 1.00 114.06 ? 91 ILE B CG2 1 ATOM 3730 C CD1 . ILE B 1 95 ? -7.684 -29.220 1.722 1.00 115.31 ? 91 ILE B CD1 1 ATOM 3731 N N . ILE B 1 96 ? -9.319 -30.044 -3.318 1.00 96.35 ? 92 ILE B N 1 ATOM 3732 C CA . ILE B 1 96 ? -8.556 -30.027 -4.564 1.00 93.06 ? 92 ILE B CA 1 ATOM 3733 C C . ILE B 1 96 ? -7.758 -28.736 -4.733 1.00 96.50 ? 92 ILE B C 1 ATOM 3734 O O . ILE B 1 96 ? -8.257 -27.645 -4.458 1.00 97.41 ? 92 ILE B O 1 ATOM 3735 C CB . ILE B 1 96 ? -9.495 -30.211 -5.779 1.00 92.91 ? 92 ILE B CB 1 ATOM 3736 C CG1 . ILE B 1 96 ? -10.125 -31.602 -5.746 1.00 96.75 ? 92 ILE B CG1 1 ATOM 3737 C CG2 . ILE B 1 96 ? -8.742 -30.020 -7.091 1.00 99.02 ? 92 ILE B CG2 1 ATOM 3738 C CD1 . ILE B 1 96 ? -11.235 -31.797 -6.745 1.00 110.71 ? 92 ILE B CD1 1 ATOM 3739 N N . SER B 1 97 ? -6.514 -28.871 -5.188 1.00 96.29 ? 93 SER B N 1 ATOM 3740 C CA . SER B 1 97 ? -5.674 -27.718 -5.493 1.00 99.51 ? 93 SER B CA 1 ATOM 3741 C C . SER B 1 97 ? -6.086 -27.114 -6.827 1.00 94.88 ? 93 SER B C 1 ATOM 3742 O O . SER B 1 97 ? -6.565 -27.817 -7.716 1.00 91.72 ? 93 SER B O 1 ATOM 3743 C CB . SER B 1 97 ? -4.196 -28.109 -5.530 1.00 100.82 ? 93 SER B CB 1 ATOM 3744 O OG . SER B 1 97 ? -3.910 -28.929 -6.649 1.00 105.42 ? 93 SER B OG 1 ATOM 3745 N N . ARG B 1 98 ? -5.866 -25.814 -6.979 1.00 98.30 ? 94 ARG B N 1 ATOM 3746 C CA . ARG B 1 98 ? -6.377 -25.092 -8.134 1.00 99.65 ? 94 ARG B CA 1 ATOM 3747 C C . ARG B 1 98 ? -5.602 -25.429 -9.398 1.00 94.04 ? 94 ARG B C 1 ATOM 3748 O O . ARG B 1 98 ? -4.732 -26.298 -9.399 1.00 86.68 ? 94 ARG B O 1 ATOM 3749 C CB . ARG B 1 98 ? -6.331 -23.588 -7.882 1.00 106.21 ? 94 ARG B CB 1 ATOM 3750 C CG . ARG B 1 98 ? -4.936 -23.033 -7.702 1.00 105.30 ? 94 ARG B CG 1 ATOM 3751 C CD . ARG B 1 98 ? -4.991 -21.539 -7.510 1.00 107.22 ? 94 ARG B CD 1 ATOM 3752 N NE . ARG B 1 98 ? -3.669 -20.962 -7.275 1.00 105.12 ? 94 ARG B NE 1 ATOM 3753 C CZ . ARG B 1 98 ? -3.153 -20.723 -6.073 1.00 115.25 ? 94 ARG B CZ 1 ATOM 3754 N NH1 . ARG B 1 98 ? -3.841 -21.004 -4.975 1.00 130.66 ? 94 ARG B NH1 1 ATOM 3755 N NH2 . ARG B 1 98 ? -1.942 -20.194 -5.968 1.00 108.91 ? 94 ARG B NH2 1 ATOM 3756 N N . ASP B 1 99 ? -5.934 -24.726 -10.473 1.00 105.86 ? 95 ASP B N 1 ATOM 3757 C CA . ASP B 1 99 ? -5.432 -25.044 -11.799 1.00 107.86 ? 95 ASP B CA 1 ATOM 3758 C C . ASP B 1 99 ? -3.932 -24.749 -11.955 1.00 108.48 ? 95 ASP B C 1 ATOM 3759 O O . ASP B 1 99 ? -3.490 -23.613 -11.802 1.00 112.74 ? 95 ASP B O 1 ATOM 3760 C CB . ASP B 1 99 ? -6.256 -24.259 -12.813 1.00 95.15 ? 95 ASP B CB 1 ATOM 3761 C CG . ASP B 1 99 ? -5.803 -24.478 -14.216 1.00 102.11 ? 95 ASP B CG 1 ATOM 3762 O OD1 . ASP B 1 99 ? -6.273 -25.441 -14.856 1.00 101.43 ? 95 ASP B OD1 1 ATOM 3763 O OD2 . ASP B 1 99 ? -4.970 -23.681 -14.686 1.00 119.90 ? 95 ASP B OD2 1 ATOM 3764 N N . VAL B 1 100 ? -3.173 -25.796 -12.279 1.00 91.38 ? 96 VAL B N 1 ATOM 3765 C CA . VAL B 1 100 ? -1.706 -25.806 -12.186 1.00 90.43 ? 96 VAL B CA 1 ATOM 3766 C C . VAL B 1 100 ? -0.928 -25.606 -13.507 1.00 94.92 ? 96 VAL B C 1 ATOM 3767 O O . VAL B 1 100 ? 0.297 -25.685 -13.479 1.00 98.67 ? 96 VAL B O 1 ATOM 3768 C CB . VAL B 1 100 ? -1.233 -27.142 -11.515 1.00 79.27 ? 96 VAL B CB 1 ATOM 3769 C CG1 . VAL B 1 100 ? 0.237 -27.092 -11.057 1.00 70.66 ? 96 VAL B CG1 1 ATOM 3770 C CG2 . VAL B 1 100 ? -2.094 -27.448 -10.306 1.00 85.92 ? 96 VAL B CG2 1 ATOM 3771 N N . HIS B 1 101 ? -1.585 -25.272 -14.627 1.00 95.24 ? 97 HIS B N 1 ATOM 3772 C CA . HIS B 1 101 ? -1.123 -25.728 -15.959 1.00 95.54 ? 97 HIS B CA 1 ATOM 3773 C C . HIS B 1 101 ? 0.391 -25.675 -16.139 1.00 93.38 ? 97 HIS B C 1 ATOM 3774 O O . HIS B 1 101 ? 1.028 -24.648 -15.909 1.00 102.69 ? 97 HIS B O 1 ATOM 3775 C CB . HIS B 1 101 ? -1.699 -24.879 -17.110 1.00 92.21 ? 97 HIS B CB 1 ATOM 3776 C CG . HIS B 1 101 ? -3.096 -24.392 -16.904 1.00 98.75 ? 97 HIS B CG 1 ATOM 3777 N ND1 . HIS B 1 101 ? -3.428 -23.056 -16.972 1.00 114.24 ? 97 HIS B ND1 1 ATOM 3778 C CD2 . HIS B 1 101 ? -4.254 -25.056 -16.685 1.00 105.33 ? 97 HIS B CD2 1 ATOM 3779 C CE1 . HIS B 1 101 ? -4.726 -22.915 -16.778 1.00 115.22 ? 97 HIS B CE1 1 ATOM 3780 N NE2 . HIS B 1 101 ? -5.250 -24.114 -16.595 1.00 114.12 ? 97 HIS B NE2 1 ATOM 3781 N N . VAL B 1 102 ? 0.945 -26.797 -16.590 1.00 87.10 ? 98 VAL B N 1 ATOM 3782 C CA . VAL B 1 102 ? 2.389 -26.972 -16.691 1.00 84.90 ? 98 VAL B CA 1 ATOM 3783 C C . VAL B 1 102 ? 2.826 -27.049 -18.148 1.00 87.19 ? 98 VAL B C 1 ATOM 3784 O O . VAL B 1 102 ? 2.117 -27.599 -18.992 1.00 88.16 ? 98 VAL B O 1 ATOM 3785 C CB . VAL B 1 102 ? 2.845 -28.247 -15.945 1.00 88.28 ? 98 VAL B CB 1 ATOM 3786 C CG1 . VAL B 1 102 ? 4.338 -28.508 -16.157 1.00 94.79 ? 98 VAL B CG1 1 ATOM 3787 C CG2 . VAL B 1 102 ? 2.525 -28.130 -14.459 1.00 86.40 ? 98 VAL B CG2 1 ATOM 3788 N N . ARG B 1 103 ? 3.998 -26.489 -18.429 1.00 98.82 ? 99 ARG B N 1 ATOM 3789 C CA . ARG B 1 103 ? 4.591 -26.544 -19.760 1.00 104.35 ? 99 ARG B CA 1 ATOM 3790 C C . ARG B 1 103 ? 6.095 -26.753 -19.667 1.00 97.65 ? 99 ARG B C 1 ATOM 3791 O O . ARG B 1 103 ? 6.710 -26.481 -18.635 1.00 99.61 ? 99 ARG B O 1 ATOM 3792 C CB . ARG B 1 103 ? 4.295 -25.261 -20.542 1.00 113.61 ? 99 ARG B CB 1 ATOM 3793 C CG . ARG B 1 103 ? 2.832 -25.060 -20.882 1.00 108.35 ? 99 ARG B CG 1 ATOM 3794 C CD . ARG B 1 103 ? 2.374 -25.994 -21.990 1.00 113.45 ? 99 ARG B CD 1 ATOM 3795 N NE . ARG B 1 103 ? 0.936 -25.888 -22.206 1.00 105.81 ? 99 ARG B NE 1 ATOM 3796 C CZ . ARG B 1 103 ? 0.352 -24.952 -22.947 1.00 104.51 ? 99 ARG B CZ 1 ATOM 3797 N NH1 . ARG B 1 103 ? 1.079 -24.027 -23.563 1.00 103.00 ? 99 ARG B NH1 1 ATOM 3798 N NH2 . ARG B 1 103 ? -0.966 -24.944 -23.072 1.00 91.74 ? 99 ARG B NH2 1 ATOM 3799 N N . ALA B 1 104 ? 6.676 -27.244 -20.756 1.00 94.20 ? 100 ALA B N 1 ATOM 3800 C CA . ALA B 1 104 ? 8.121 -27.374 -20.873 1.00 88.08 ? 100 ALA B CA 1 ATOM 3801 C C . ALA B 1 104 ? 8.532 -26.956 -22.277 1.00 98.97 ? 100 ALA B C 1 ATOM 3802 O O . ALA B 1 104 ? 7.788 -27.173 -23.235 1.00 119.04 ? 100 ALA B O 1 ATOM 3803 C CB . ALA B 1 104 ? 8.567 -28.797 -20.574 1.00 86.20 ? 100 ALA B CB 1 ATOM 3804 N N . VAL B 1 105 ? 9.711 -26.353 -22.393 1.00 89.88 ? 101 VAL B N 1 ATOM 3805 C CA . VAL B 1 105 ? 10.157 -25.783 -23.660 1.00 92.45 ? 101 VAL B CA 1 ATOM 3806 C C . VAL B 1 105 ? 11.514 -26.318 -24.091 1.00 96.05 ? 101 VAL B C 1 ATOM 3807 O O . VAL B 1 105 ? 12.514 -26.159 -23.391 1.00 95.56 ? 101 VAL B O 1 ATOM 3808 C CB . VAL B 1 105 ? 10.239 -24.242 -23.581 1.00 95.97 ? 101 VAL B CB 1 ATOM 3809 C CG1 . VAL B 1 105 ? 10.658 -23.656 -24.928 1.00 95.30 ? 101 VAL B CG1 1 ATOM 3810 C CG2 . VAL B 1 105 ? 8.903 -23.662 -23.137 1.00 79.99 ? 101 VAL B CG2 1 ATOM 3811 N N . VAL B 1 106 ? 11.532 -26.965 -25.251 1.00 97.49 ? 102 VAL B N 1 ATOM 3812 C CA . VAL B 1 106 ? 12.776 -27.279 -25.935 1.00 89.99 ? 102 VAL B CA 1 ATOM 3813 C C . VAL B 1 106 ? 13.184 -26.053 -26.740 1.00 106.23 ? 102 VAL B C 1 ATOM 3814 O O . VAL B 1 106 ? 12.331 -25.331 -27.256 1.00 108.71 ? 102 VAL B O 1 ATOM 3815 C CB . VAL B 1 106 ? 12.634 -28.502 -26.856 1.00 91.91 ? 102 VAL B CB 1 ATOM 3816 C CG1 . VAL B 1 106 ? 13.948 -28.792 -27.574 1.00 96.97 ? 102 VAL B CG1 1 ATOM 3817 C CG2 . VAL B 1 106 ? 12.174 -29.712 -26.055 1.00 90.72 ? 102 VAL B CG2 1 ATOM 3818 N N . ILE B 1 107 ? 14.486 -25.815 -26.842 1.00 111.76 ? 103 ILE B N 1 ATOM 3819 C CA . ILE B 1 107 ? 14.990 -24.624 -27.512 1.00 102.39 ? 103 ILE B CA 1 ATOM 3820 C C . ILE B 1 107 ? 14.762 -24.703 -29.021 1.00 108.47 ? 103 ILE B C 1 ATOM 3821 O O . ILE B 1 107 ? 15.210 -25.642 -29.680 1.00 109.27 ? 103 ILE B O 1 ATOM 3822 C CB . ILE B 1 107 ? 16.490 -24.424 -27.212 1.00 99.60 ? 103 ILE B CB 1 ATOM 3823 C CG1 . ILE B 1 107 ? 16.689 -24.232 -25.705 1.00 95.82 ? 103 ILE B CG1 1 ATOM 3824 C CG2 . ILE B 1 107 ? 17.048 -23.234 -27.993 1.00 110.17 ? 103 ILE B CG2 1 ATOM 3825 C CD1 . ILE B 1 107 ? 18.133 -24.172 -25.262 1.00 109.99 ? 103 ILE B CD1 1 ATOM 3826 N N . GLN B 1 108 ? 14.057 -23.707 -29.553 1.00 105.68 ? 104 GLN B N 1 ATOM 3827 C CA . GLN B 1 108 ? 13.759 -23.630 -30.981 1.00 108.89 ? 104 GLN B CA 1 ATOM 3828 C C . GLN B 1 108 ? 14.749 -22.740 -31.726 1.00 115.73 ? 104 GLN B C 1 ATOM 3829 O O . GLN B 1 108 ? 14.695 -22.641 -32.954 1.00 110.21 ? 104 GLN B O 1 ATOM 3830 C CB . GLN B 1 108 ? 12.337 -23.098 -31.200 1.00 109.94 ? 104 GLN B CB 1 ATOM 3831 C CG . GLN B 1 108 ? 11.245 -24.156 -31.175 1.00 110.83 ? 104 GLN B CG 1 ATOM 3832 C CD . GLN B 1 108 ? 10.423 -24.126 -29.902 1.00 113.28 ? 104 GLN B CD 1 ATOM 3833 O OE1 . GLN B 1 108 ? 9.194 -24.074 -29.946 1.00 99.81 ? 104 GLN B OE1 1 ATOM 3834 N NE2 . GLN B 1 108 ? 11.096 -24.168 -28.760 1.00 111.33 ? 104 GLN B NE2 1 ATOM 3835 N N . SER B 1 109 ? 15.656 -22.110 -30.983 1.00 113.03 ? 105 SER B N 1 ATOM 3836 C CA . SER B 1 109 ? 16.547 -21.099 -31.544 1.00 107.89 ? 105 SER B CA 1 ATOM 3837 C C . SER B 1 109 ? 15.714 -20.050 -32.279 1.00 115.80 ? 105 SER B C 1 ATOM 3838 O O . SER B 1 109 ? 15.789 -19.925 -33.500 1.00 117.90 ? 105 SER B O 1 ATOM 3839 C CB . SER B 1 109 ? 17.578 -21.732 -32.484 1.00 116.11 ? 105 SER B CB 1 ATOM 3840 O OG . SER B 1 109 ? 18.400 -22.657 -31.793 1.00 117.51 ? 105 SER B OG 1 ATOM 3841 N N . TYR B 1 110 ? 14.911 -19.312 -31.516 1.00 122.18 ? 106 TYR B N 1 ATOM 3842 C CA . TYR B 1 110 ? 13.972 -18.337 -32.068 1.00 113.04 ? 106 TYR B CA 1 ATOM 3843 C C . TYR B 1 110 ? 14.648 -17.269 -32.923 1.00 108.43 ? 106 TYR B C 1 ATOM 3844 O O . TYR B 1 110 ? 15.772 -16.851 -32.643 1.00 111.64 ? 106 TYR B O 1 ATOM 3845 C CB . TYR B 1 110 ? 13.195 -17.658 -30.933 1.00 103.93 ? 106 TYR B CB 1 ATOM 3846 C CG . TYR B 1 110 ? 14.060 -16.831 -30.003 1.00 101.82 ? 106 TYR B CG 1 ATOM 3847 C CD1 . TYR B 1 110 ? 14.872 -17.438 -29.055 1.00 112.23 ? 106 TYR B CD1 1 ATOM 3848 C CD2 . TYR B 1 110 ? 14.060 -15.443 -30.069 1.00 94.81 ? 106 TYR B CD2 1 ATOM 3849 C CE1 . TYR B 1 110 ? 15.665 -16.691 -28.205 1.00 115.95 ? 106 TYR B CE1 1 ATOM 3850 C CE2 . TYR B 1 110 ? 14.849 -14.687 -29.219 1.00 96.67 ? 106 TYR B CE2 1 ATOM 3851 C CZ . TYR B 1 110 ? 15.649 -15.317 -28.290 1.00 104.98 ? 106 TYR B CZ 1 ATOM 3852 O OH . TYR B 1 110 ? 16.438 -14.574 -27.441 1.00 101.92 ? 106 TYR B OH 1 ATOM 3853 N N . GLU B 1 111 ? 13.943 -16.841 -33.968 1.00 105.59 ? 107 GLU B N 1 ATOM 3854 C CA . GLU B 1 111 ? 14.387 -15.750 -34.829 1.00 105.43 ? 107 GLU B CA 1 ATOM 3855 C C . GLU B 1 111 ? 13.448 -14.562 -34.668 1.00 99.97 ? 107 GLU B C 1 ATOM 3856 O O . GLU B 1 111 ? 12.273 -14.733 -34.346 1.00 100.16 ? 107 GLU B O 1 ATOM 3857 C CB . GLU B 1 111 ? 14.438 -16.194 -36.292 1.00 97.72 ? 107 GLU B CB 1 ATOM 3858 C CG . GLU B 1 111 ? 15.776 -16.775 -36.712 1.00 117.05 ? 107 GLU B CG 1 ATOM 3859 C CD . GLU B 1 111 ? 16.119 -18.041 -35.962 1.00 118.69 ? 107 GLU B CD 1 ATOM 3860 O OE1 . GLU B 1 111 ? 15.397 -19.046 -36.133 1.00 129.79 ? 107 GLU B OE1 1 ATOM 3861 O OE2 . GLU B 1 111 ? 17.107 -18.031 -35.197 1.00 113.90 ? 107 GLU B OE2 1 ATOM 3862 N N . SER B 1 112 ? 13.976 -13.361 -34.880 1.00 101.85 ? 108 SER B N 1 ATOM 3863 C CA . SER B 1 112 ? 13.179 -12.145 -34.782 1.00 100.04 ? 108 SER B CA 1 ATOM 3864 C C . SER B 1 112 ? 13.471 -11.220 -35.955 1.00 81.77 ? 108 SER B C 1 ATOM 3865 O O . SER B 1 112 ? 14.626 -10.907 -36.248 1.00 90.09 ? 108 SER B O 1 ATOM 3866 C CB . SER B 1 112 ? 13.447 -11.430 -33.457 1.00 91.69 ? 108 SER B CB 1 ATOM 3867 O OG . SER B 1 112 ? 14.821 -11.137 -33.300 1.00 79.50 ? 108 SER B OG 1 ATOM 3868 N N . GLU B 1 113 ? 12.404 -10.794 -36.621 1.00 87.51 ? 109 GLU B N 1 ATOM 3869 C CA . GLU B 1 113 ? 12.497 -9.955 -37.807 1.00 94.70 ? 109 GLU B CA 1 ATOM 3870 C C . GLU B 1 113 ? 12.160 -8.508 -37.459 1.00 97.96 ? 109 GLU B C 1 ATOM 3871 O O . GLU B 1 113 ? 11.130 -8.235 -36.843 1.00 112.22 ? 109 GLU B O 1 ATOM 3872 C CB . GLU B 1 113 ? 11.555 -10.488 -38.894 1.00 103.52 ? 109 GLU B CB 1 ATOM 3873 C CG . GLU B 1 113 ? 11.459 -9.643 -40.156 1.00 109.80 ? 109 GLU B CG 1 ATOM 3874 C CD . GLU B 1 113 ? 10.018 -9.386 -40.567 1.00 117.20 ? 109 GLU B CD 1 ATOM 3875 O OE1 . GLU B 1 113 ? 9.343 -8.578 -39.895 1.00 137.00 ? 109 GLU B OE1 1 ATOM 3876 O OE2 . GLU B 1 113 ? 9.555 -9.995 -41.554 1.00 112.82 ? 109 GLU B OE2 1 ATOM 3877 N N . ALA B 1 114 ? 13.035 -7.585 -37.849 1.00 81.31 ? 110 ALA B N 1 ATOM 3878 C CA . ALA B 1 114 ? 12.775 -6.159 -37.676 1.00 76.38 ? 110 ALA B CA 1 ATOM 3879 C C . ALA B 1 114 ? 12.084 -5.639 -38.926 1.00 86.16 ? 110 ALA B C 1 ATOM 3880 O O . ALA B 1 114 ? 12.662 -5.640 -40.014 1.00 81.02 ? 110 ALA B O 1 ATOM 3881 C CB . ALA B 1 114 ? 14.065 -5.397 -37.410 1.00 92.70 ? 110 ALA B CB 1 ATOM 3882 N N . ASP B 1 115 ? 10.842 -5.195 -38.766 1.00 93.97 ? 111 ASP B N 1 ATOM 3883 C CA . ASP B 1 115 ? 9.997 -4.880 -39.909 1.00 92.72 ? 111 ASP B CA 1 ATOM 3884 C C . ASP B 1 115 ? 10.203 -3.453 -40.400 1.00 82.89 ? 111 ASP B C 1 ATOM 3885 O O . ASP B 1 115 ? 10.187 -2.504 -39.616 1.00 77.61 ? 111 ASP B O 1 ATOM 3886 C CB . ASP B 1 115 ? 8.524 -5.096 -39.551 1.00 102.43 ? 111 ASP B CB 1 ATOM 3887 C CG . ASP B 1 115 ? 7.664 -5.391 -40.769 1.00 119.87 ? 111 ASP B CG 1 ATOM 3888 O OD1 . ASP B 1 115 ? 8.071 -6.238 -41.592 1.00 131.93 ? 111 ASP B OD1 1 ATOM 3889 O OD2 . ASP B 1 115 ? 6.586 -4.775 -40.907 1.00 121.30 ? 111 ASP B OD2 1 ATOM 3890 N N . ASN B 1 116 ? 10.402 -3.314 -41.707 1.00 76.94 ? 112 ASN B N 1 ATOM 3891 C CA . ASN B 1 116 ? 10.462 -2.005 -42.337 1.00 70.20 ? 112 ASN B CA 1 ATOM 3892 C C . ASN B 1 116 ? 9.130 -1.282 -42.182 1.00 78.07 ? 112 ASN B C 1 ATOM 3893 O O . ASN B 1 116 ? 8.069 -1.887 -42.339 1.00 92.27 ? 112 ASN B O 1 ATOM 3894 C CB . ASN B 1 116 ? 10.820 -2.138 -43.820 1.00 69.96 ? 112 ASN B CB 1 ATOM 3895 C CG . ASN B 1 116 ? 12.158 -2.819 -44.041 1.00 82.88 ? 112 ASN B CG 1 ATOM 3896 O OD1 . ASN B 1 116 ? 13.063 -2.718 -43.214 1.00 83.68 ? 112 ASN B OD1 1 ATOM 3897 N ND2 . ASN B 1 116 ? 12.289 -3.518 -45.164 1.00 84.10 ? 112 ASN B ND2 1 ATOM 3898 N N . GLU B 1 117 ? 9.191 0.008 -41.865 1.00 71.48 ? 113 GLU B N 1 ATOM 3899 C CA . GLU B 1 117 ? 7.992 0.824 -41.717 1.00 76.86 ? 113 GLU B CA 1 ATOM 3900 C C . GLU B 1 117 ? 8.090 2.051 -42.617 1.00 72.97 ? 113 GLU B C 1 ATOM 3901 O O . GLU B 1 117 ? 9.086 2.774 -42.598 1.00 69.14 ? 113 GLU B O 1 ATOM 3902 C CB . GLU B 1 117 ? 7.791 1.228 -40.254 1.00 80.88 ? 113 GLU B CB 1 ATOM 3903 C CG . GLU B 1 117 ? 7.432 0.057 -39.342 1.00 96.35 ? 113 GLU B CG 1 ATOM 3904 C CD . GLU B 1 117 ? 6.020 -0.460 -39.570 1.00 101.18 ? 113 GLU B CD 1 ATOM 3905 O OE1 . GLU B 1 117 ? 5.639 -1.458 -38.921 1.00 78.94 ? 113 GLU B OE1 1 ATOM 3906 O OE2 . GLU B 1 117 ? 5.289 0.129 -40.394 1.00 103.90 ? 113 GLU B OE2 1 ATOM 3907 N N . TYR B 1 118 ? 7.042 2.266 -43.406 1.00 78.56 ? 114 TYR B N 1 ATOM 3908 C CA . TYR B 1 118 ? 7.033 3.287 -44.446 1.00 73.13 ? 114 TYR B CA 1 ATOM 3909 C C . TYR B 1 118 ? 6.170 4.458 -43.991 1.00 65.58 ? 114 TYR B C 1 ATOM 3910 O O . TYR B 1 118 ? 4.994 4.281 -43.673 1.00 70.42 ? 114 TYR B O 1 ATOM 3911 C CB . TYR B 1 118 ? 6.518 2.697 -45.764 1.00 69.56 ? 114 TYR B CB 1 ATOM 3912 C CG . TYR B 1 118 ? 7.433 1.642 -46.365 1.00 72.73 ? 114 TYR B CG 1 ATOM 3913 C CD1 . TYR B 1 118 ? 7.867 0.553 -45.616 1.00 80.37 ? 114 TYR B CD1 1 ATOM 3914 C CD2 . TYR B 1 118 ? 7.856 1.731 -47.684 1.00 71.38 ? 114 TYR B CD2 1 ATOM 3915 C CE1 . TYR B 1 118 ? 8.702 -0.405 -46.159 1.00 82.28 ? 114 TYR B CE1 1 ATOM 3916 C CE2 . TYR B 1 118 ? 8.689 0.774 -48.236 1.00 77.99 ? 114 TYR B CE2 1 ATOM 3917 C CZ . TYR B 1 118 ? 9.108 -0.290 -47.468 1.00 77.18 ? 114 TYR B CZ 1 ATOM 3918 O OH . TYR B 1 118 ? 9.938 -1.246 -48.011 1.00 59.41 ? 114 TYR B OH 1 ATOM 3919 N N . VAL B 1 119 ? 6.756 5.653 -43.961 1.00 72.97 ? 115 VAL B N 1 ATOM 3920 C CA . VAL B 1 119 ? 6.129 6.792 -43.299 1.00 66.83 ? 115 VAL B CA 1 ATOM 3921 C C . VAL B 1 119 ? 6.275 8.095 -44.079 1.00 67.33 ? 115 VAL B C 1 ATOM 3922 O O . VAL B 1 119 ? 7.280 8.326 -44.752 1.00 71.77 ? 115 VAL B O 1 ATOM 3923 C CB . VAL B 1 119 ? 6.725 7.000 -41.884 1.00 65.81 ? 115 VAL B CB 1 ATOM 3924 C CG1 . VAL B 1 119 ? 5.974 8.090 -41.128 1.00 67.10 ? 115 VAL B CG1 1 ATOM 3925 C CG2 . VAL B 1 119 ? 6.706 5.698 -41.095 1.00 66.01 ? 115 VAL B CG2 1 ATOM 3926 N N . ILE B 1 120 ? 5.251 8.937 -43.978 1.00 76.08 ? 116 ILE B N 1 ATOM 3927 C CA . ILE B 1 120 ? 5.298 10.301 -44.492 1.00 78.06 ? 116 ILE B CA 1 ATOM 3928 C C . ILE B 1 120 ? 5.872 11.216 -43.417 1.00 68.00 ? 116 ILE B C 1 ATOM 3929 O O . ILE B 1 120 ? 5.458 11.148 -42.260 1.00 67.80 ? 116 ILE B O 1 ATOM 3930 C CB . ILE B 1 120 ? 3.899 10.800 -44.905 1.00 67.25 ? 116 ILE B CB 1 ATOM 3931 C CG1 . ILE B 1 120 ? 3.334 9.923 -46.025 1.00 64.83 ? 116 ILE B CG1 1 ATOM 3932 C CG2 . ILE B 1 120 ? 3.958 12.259 -45.347 1.00 65.36 ? 116 ILE B CG2 1 ATOM 3933 C CD1 . ILE B 1 120 ? 1.863 10.143 -46.297 1.00 87.50 ? 116 ILE B CD1 1 ATOM 3934 N N . ARG B 1 121 ? 6.814 12.075 -43.796 1.00 60.98 ? 117 ARG B N 1 ATOM 3935 C CA . ARG B 1 121 ? 7.493 12.929 -42.824 1.00 71.10 ? 117 ARG B CA 1 ATOM 3936 C C . ARG B 1 121 ? 6.505 13.794 -42.045 1.00 60.57 ? 117 ARG B C 1 ATOM 3937 O O . ARG B 1 121 ? 5.556 14.336 -42.612 1.00 65.19 ? 117 ARG B O 1 ATOM 3938 C CB . ARG B 1 121 ? 8.528 13.823 -43.511 1.00 67.13 ? 117 ARG B CB 1 ATOM 3939 C CG . ARG B 1 121 ? 9.469 14.496 -42.524 1.00 62.19 ? 117 ARG B CG 1 ATOM 3940 C CD . ARG B 1 121 ? 10.562 15.299 -43.203 1.00 65.38 ? 117 ARG B CD 1 ATOM 3941 N NE . ARG B 1 121 ? 10.022 16.325 -44.090 1.00 68.27 ? 117 ARG B NE 1 ATOM 3942 C CZ . ARG B 1 121 ? 9.850 16.177 -45.401 1.00 60.77 ? 117 ARG B CZ 1 ATOM 3943 N NH1 . ARG B 1 121 ? 9.350 17.175 -46.113 1.00 50.84 ? 117 ARG B NH1 1 ATOM 3944 N NH2 . ARG B 1 121 ? 10.177 15.041 -46.004 1.00 59.68 ? 117 ARG B NH2 1 ATOM 3945 N N . GLY B 1 122 ? 6.743 13.911 -40.740 1.00 60.25 ? 118 GLY B N 1 ATOM 3946 C CA . GLY B 1 122 ? 5.880 14.674 -39.857 1.00 67.91 ? 118 GLY B CA 1 ATOM 3947 C C . GLY B 1 122 ? 5.003 13.770 -39.010 1.00 68.82 ? 118 GLY B C 1 ATOM 3948 O O . GLY B 1 122 ? 4.485 14.193 -37.976 1.00 72.97 ? 118 GLY B O 1 ATOM 3949 N N . ASN B 1 123 ? 4.851 12.521 -39.443 1.00 67.02 ? 119 ASN B N 1 ATOM 3950 C CA . ASN B 1 123 ? 3.991 11.565 -38.750 1.00 61.16 ? 119 ASN B CA 1 ATOM 3951 C C . ASN B 1 123 ? 4.763 10.648 -37.810 1.00 60.59 ? 119 ASN B C 1 ATOM 3952 O O . ASN B 1 123 ? 5.741 10.014 -38.203 1.00 73.10 ? 119 ASN B O 1 ATOM 3953 C CB . ASN B 1 123 ? 3.214 10.719 -39.762 1.00 56.98 ? 119 ASN B CB 1 ATOM 3954 C CG . ASN B 1 123 ? 1.744 11.078 -39.814 1.00 54.99 ? 119 ASN B CG 1 ATOM 3955 O OD1 . ASN B 1 123 ? 1.247 11.556 -40.833 1.00 56.38 ? 119 ASN B OD1 1 ATOM 3956 N ND2 . ASN B 1 123 ? 1.037 10.842 -38.714 1.00 50.63 ? 119 ASN B ND2 1 ATOM 3957 N N . SER B 1 124 ? 4.303 10.580 -36.564 1.00 62.26 ? 120 SER B N 1 ATOM 3958 C CA . SER B 1 124 ? 4.886 9.691 -35.569 1.00 76.54 ? 120 SER B CA 1 ATOM 3959 C C . SER B 1 124 ? 4.598 8.240 -35.943 1.00 82.60 ? 120 SER B C 1 ATOM 3960 O O . SER B 1 124 ? 3.475 7.905 -36.321 1.00 92.99 ? 120 SER B O 1 ATOM 3961 C CB . SER B 1 124 ? 4.330 10.009 -34.179 1.00 84.91 ? 120 SER B CB 1 ATOM 3962 O OG . SER B 1 124 ? 4.422 11.396 -33.901 1.00 91.49 ? 120 SER B OG 1 ATOM 3963 N N . VAL B 1 125 ? 5.615 7.387 -35.838 1.00 85.83 ? 121 VAL B N 1 ATOM 3964 C CA . VAL B 1 125 ? 5.497 5.988 -36.245 1.00 83.70 ? 121 VAL B CA 1 ATOM 3965 C C . VAL B 1 125 ? 5.946 5.040 -35.139 1.00 82.02 ? 121 VAL B C 1 ATOM 3966 O O . VAL B 1 125 ? 6.803 5.381 -34.322 1.00 80.45 ? 121 VAL B O 1 ATOM 3967 C CB . VAL B 1 125 ? 6.326 5.704 -37.521 1.00 67.37 ? 121 VAL B CB 1 ATOM 3968 C CG1 . VAL B 1 125 ? 7.822 5.879 -37.250 1.00 64.78 ? 121 VAL B CG1 1 ATOM 3969 C CG2 . VAL B 1 125 ? 6.023 4.303 -38.065 1.00 77.09 ? 121 VAL B CG2 1 ATOM 3970 N N . VAL B 1 126 ? 5.353 3.850 -35.127 1.00 87.81 ? 122 VAL B N 1 ATOM 3971 C CA . VAL B 1 126 ? 5.727 2.796 -34.191 1.00 87.10 ? 122 VAL B CA 1 ATOM 3972 C C . VAL B 1 126 ? 6.429 1.661 -34.930 1.00 82.65 ? 122 VAL B C 1 ATOM 3973 O O . VAL B 1 126 ? 5.925 1.157 -35.935 1.00 84.38 ? 122 VAL B O 1 ATOM 3974 C CB . VAL B 1 126 ? 4.499 2.236 -33.448 1.00 77.85 ? 122 VAL B CB 1 ATOM 3975 C CG1 . VAL B 1 126 ? 4.928 1.205 -32.408 1.00 69.45 ? 122 VAL B CG1 1 ATOM 3976 C CG2 . VAL B 1 126 ? 3.714 3.369 -32.795 1.00 103.92 ? 122 VAL B CG2 1 ATOM 3977 N N . MET B 1 127 ? 7.595 1.267 -34.424 1.00 81.89 ? 123 MET B N 1 ATOM 3978 C CA . MET B 1 127 ? 8.348 0.155 -34.991 1.00 81.13 ? 123 MET B CA 1 ATOM 3979 C C . MET B 1 127 ? 8.137 -1.112 -34.176 1.00 80.83 ? 123 MET B C 1 ATOM 3980 O O . MET B 1 127 ? 8.271 -1.103 -32.951 1.00 69.90 ? 123 MET B O 1 ATOM 3981 C CB . MET B 1 127 ? 9.838 0.486 -35.050 1.00 98.66 ? 123 MET B CB 1 ATOM 3982 C CG . MET B 1 127 ? 10.197 1.534 -36.083 1.00 104.37 ? 123 MET B CG 1 ATOM 3983 S SD . MET B 1 127 ? 11.948 1.489 -36.507 1.00 101.54 ? 123 MET B SD 1 ATOM 3984 C CE . MET B 1 127 ? 12.025 -0.027 -37.459 1.00 82.50 ? 123 MET B CE 1 ATOM 3985 N N . LYS B 1 128 ? 7.806 -2.199 -34.867 1.00 91.22 ? 124 LYS B N 1 ATOM 3986 C CA . LYS B 1 128 ? 7.630 -3.498 -34.234 1.00 85.77 ? 124 LYS B CA 1 ATOM 3987 C C . LYS B 1 128 ? 8.635 -4.507 -34.769 1.00 89.77 ? 124 LYS B C 1 ATOM 3988 O O . LYS B 1 128 ? 8.698 -4.754 -35.974 1.00 93.34 ? 124 LYS B O 1 ATOM 3989 C CB . LYS B 1 128 ? 6.210 -4.023 -34.460 1.00 77.95 ? 124 LYS B CB 1 ATOM 3990 C CG . LYS B 1 128 ? 5.128 -3.250 -33.730 1.00 98.54 ? 124 LYS B CG 1 ATOM 3991 C CD . LYS B 1 128 ? 3.763 -3.872 -33.968 1.00 114.13 ? 124 LYS B CD 1 ATOM 3992 C CE . LYS B 1 128 ? 2.667 -3.108 -33.249 1.00 108.12 ? 124 LYS B CE 1 ATOM 3993 N NZ . LYS B 1 128 ? 1.322 -3.694 -33.507 1.00 126.46 ? 124 LYS B NZ 1 ATOM 3994 N N . CYS B 1 129 ? 9.425 -5.080 -33.868 1.00 79.90 ? 125 CYS B N 1 ATOM 3995 C CA . CYS B 1 129 ? 10.234 -6.242 -34.199 1.00 79.62 ? 125 CYS B CA 1 ATOM 3996 C C . CYS B 1 129 ? 9.384 -7.462 -33.883 1.00 76.06 ? 125 CYS B C 1 ATOM 3997 O O . CYS B 1 129 ? 9.029 -7.694 -32.727 1.00 67.80 ? 125 CYS B O 1 ATOM 3998 C CB . CYS B 1 129 ? 11.545 -6.257 -33.414 1.00 101.45 ? 125 CYS B CB 1 ATOM 3999 S SG . CYS B 1 129 ? 12.684 -7.560 -33.931 1.00 130.82 ? 125 CYS B SG 1 ATOM 4000 N N . GLU B 1 130 ? 9.048 -8.233 -34.911 1.00 81.03 ? 126 GLU B N 1 ATOM 4001 C CA . GLU B 1 130 ? 8.026 -9.264 -34.778 1.00 83.87 ? 126 GLU B CA 1 ATOM 4002 C C . GLU B 1 130 ? 8.614 -10.606 -34.353 1.00 91.87 ? 126 GLU B C 1 ATOM 4003 O O . GLU B 1 130 ? 9.386 -11.228 -35.084 1.00 92.67 ? 126 GLU B O 1 ATOM 4004 C CB . GLU B 1 130 ? 7.248 -9.416 -36.092 1.00 90.61 ? 126 GLU B CB 1 ATOM 4005 C CG . GLU B 1 130 ? 8.092 -9.714 -37.320 1.00 105.56 ? 126 GLU B CG 1 ATOM 4006 C CD . GLU B 1 130 ? 7.326 -9.498 -38.611 1.00 126.07 ? 126 GLU B CD 1 ATOM 4007 O OE1 . GLU B 1 130 ? 7.398 -8.380 -39.164 1.00 133.93 ? 126 GLU B OE1 1 ATOM 4008 O OE2 . GLU B 1 130 ? 6.649 -10.442 -39.072 1.00 129.91 ? 126 GLU B OE2 1 ATOM 4009 N N . ILE B 1 131 ? 8.239 -11.035 -33.152 1.00 91.63 ? 127 ILE B N 1 ATOM 4010 C CA . ILE B 1 131 ? 8.618 -12.341 -32.629 1.00 79.22 ? 127 ILE B CA 1 ATOM 4011 C C . ILE B 1 131 ? 7.522 -13.342 -33.002 1.00 100.15 ? 127 ILE B C 1 ATOM 4012 O O . ILE B 1 131 ? 6.340 -12.996 -32.965 1.00 103.69 ? 127 ILE B O 1 ATOM 4013 C CB . ILE B 1 131 ? 8.826 -12.300 -31.092 1.00 71.32 ? 127 ILE B CB 1 ATOM 4014 C CG1 . ILE B 1 131 ? 10.113 -11.549 -30.742 1.00 74.96 ? 127 ILE B CG1 1 ATOM 4015 C CG2 . ILE B 1 131 ? 8.915 -13.697 -30.503 1.00 72.09 ? 127 ILE B CG2 1 ATOM 4016 C CD1 . ILE B 1 131 ? 10.012 -10.042 -30.841 1.00 86.40 ? 127 ILE B CD1 1 ATOM 4017 N N . PRO B 1 132 ? 7.903 -14.578 -33.379 1.00 87.35 ? 128 PRO B N 1 ATOM 4018 C CA . PRO B 1 132 ? 6.887 -15.576 -33.745 1.00 80.49 ? 128 PRO B CA 1 ATOM 4019 C C . PRO B 1 132 ? 5.860 -15.808 -32.636 1.00 77.51 ? 128 PRO B C 1 ATOM 4020 O O . PRO B 1 132 ? 6.187 -15.690 -31.456 1.00 77.76 ? 128 PRO B O 1 ATOM 4021 C CB . PRO B 1 132 ? 7.712 -16.839 -34.007 1.00 77.96 ? 128 PRO B CB 1 ATOM 4022 C CG . PRO B 1 132 ? 9.066 -16.337 -34.367 1.00 84.75 ? 128 PRO B CG 1 ATOM 4023 C CD . PRO B 1 132 ? 9.270 -15.096 -33.563 1.00 86.13 ? 128 PRO B CD 1 ATOM 4024 N N . SER B 1 133 ? 4.633 -16.136 -33.029 1.00 81.02 ? 129 SER B N 1 ATOM 4025 C CA . SER B 1 133 ? 3.507 -16.214 -32.104 1.00 85.11 ? 129 SER B CA 1 ATOM 4026 C C . SER B 1 133 ? 3.690 -17.263 -31.009 1.00 81.02 ? 129 SER B C 1 ATOM 4027 O O . SER B 1 133 ? 3.214 -17.080 -29.888 1.00 78.69 ? 129 SER B O 1 ATOM 4028 C CB . SER B 1 133 ? 2.224 -16.509 -32.883 1.00 74.73 ? 129 SER B CB 1 ATOM 4029 O OG . SER B 1 133 ? 2.367 -17.682 -33.661 1.00 86.88 ? 129 SER B OG 1 ATOM 4030 N N . TYR B 1 134 ? 4.377 -18.356 -31.330 1.00 69.94 ? 130 TYR B N 1 ATOM 4031 C CA . TYR B 1 134 ? 4.492 -19.473 -30.394 1.00 77.23 ? 130 TYR B CA 1 ATOM 4032 C C . TYR B 1 134 ? 5.536 -19.216 -29.312 1.00 77.61 ? 130 TYR B C 1 ATOM 4033 O O . TYR B 1 134 ? 5.330 -19.566 -28.148 1.00 70.17 ? 130 TYR B O 1 ATOM 4034 C CB . TYR B 1 134 ? 4.819 -20.779 -31.133 1.00 75.38 ? 130 TYR B CB 1 ATOM 4035 C CG . TYR B 1 134 ? 5.881 -20.695 -32.214 1.00 74.98 ? 130 TYR B CG 1 ATOM 4036 C CD1 . TYR B 1 134 ? 7.227 -20.861 -31.917 1.00 84.03 ? 130 TYR B CD1 1 ATOM 4037 C CD2 . TYR B 1 134 ? 5.528 -20.484 -33.540 1.00 77.04 ? 130 TYR B CD2 1 ATOM 4038 C CE1 . TYR B 1 134 ? 8.193 -20.797 -32.912 1.00 82.90 ? 130 TYR B CE1 1 ATOM 4039 C CE2 . TYR B 1 134 ? 6.484 -20.420 -34.537 1.00 76.21 ? 130 TYR B CE2 1 ATOM 4040 C CZ . TYR B 1 134 ? 7.814 -20.578 -34.219 1.00 77.89 ? 130 TYR B CZ 1 ATOM 4041 O OH . TYR B 1 134 ? 8.766 -20.514 -35.211 1.00 69.22 ? 130 TYR B OH 1 ATOM 4042 N N . VAL B 1 135 ? 6.650 -18.605 -29.698 1.00 84.99 ? 131 VAL B N 1 ATOM 4043 C CA . VAL B 1 135 ? 7.721 -18.294 -28.756 1.00 75.01 ? 131 VAL B CA 1 ATOM 4044 C C . VAL B 1 135 ? 7.417 -16.994 -28.006 1.00 81.78 ? 131 VAL B C 1 ATOM 4045 O O . VAL B 1 135 ? 8.004 -16.720 -26.958 1.00 81.45 ? 131 VAL B O 1 ATOM 4046 C CB . VAL B 1 135 ? 9.087 -18.183 -29.481 1.00 74.77 ? 131 VAL B CB 1 ATOM 4047 C CG1 . VAL B 1 135 ? 9.075 -17.035 -30.480 1.00 75.37 ? 131 VAL B CG1 1 ATOM 4048 C CG2 . VAL B 1 135 ? 10.231 -18.026 -28.480 1.00 92.38 ? 131 VAL B CG2 1 ATOM 4049 N N . ALA B 1 136 ? 6.478 -16.211 -28.536 1.00 78.73 ? 132 ALA B N 1 ATOM 4050 C CA . ALA B 1 136 ? 6.131 -14.909 -27.963 1.00 74.72 ? 132 ALA B CA 1 ATOM 4051 C C . ALA B 1 136 ? 5.594 -15.023 -26.537 1.00 69.32 ? 132 ALA B C 1 ATOM 4052 O O . ALA B 1 136 ? 5.516 -14.027 -25.817 1.00 67.47 ? 132 ALA B O 1 ATOM 4053 C CB . ALA B 1 136 ? 5.108 -14.200 -28.847 1.00 72.23 ? 132 ALA B CB 1 ATOM 4054 N N . ASP B 1 137 ? 5.229 -16.236 -26.132 1.00 70.24 ? 133 ASP B N 1 ATOM 4055 C CA . ASP B 1 137 ? 4.732 -16.479 -24.781 1.00 80.57 ? 133 ASP B CA 1 ATOM 4056 C C . ASP B 1 137 ? 5.811 -16.223 -23.725 1.00 83.67 ? 133 ASP B C 1 ATOM 4057 O O . ASP B 1 137 ? 5.517 -16.172 -22.530 1.00 82.63 ? 133 ASP B O 1 ATOM 4058 C CB . ASP B 1 137 ? 4.213 -17.914 -24.656 1.00 80.67 ? 133 ASP B CB 1 ATOM 4059 C CG . ASP B 1 137 ? 3.123 -18.234 -25.662 1.00 88.36 ? 133 ASP B CG 1 ATOM 4060 O OD1 . ASP B 1 137 ? 2.279 -17.353 -25.933 1.00 108.54 ? 133 ASP B OD1 1 ATOM 4061 O OD2 . ASP B 1 137 ? 3.111 -19.369 -26.184 1.00 83.11 ? 133 ASP B OD2 1 ATOM 4062 N N . PHE B 1 138 ? 7.056 -16.068 -24.176 1.00 82.83 ? 134 PHE B N 1 ATOM 4063 C CA . PHE B 1 138 ? 8.201 -15.919 -23.283 1.00 84.25 ? 134 PHE B CA 1 ATOM 4064 C C . PHE B 1 138 ? 9.066 -14.716 -23.654 1.00 89.91 ? 134 PHE B C 1 ATOM 4065 O O . PHE B 1 138 ? 9.185 -13.763 -22.882 1.00 102.18 ? 134 PHE B O 1 ATOM 4066 C CB . PHE B 1 138 ? 9.039 -17.196 -23.311 1.00 80.90 ? 134 PHE B CB 1 ATOM 4067 C CG . PHE B 1 138 ? 8.217 -18.450 -23.264 1.00 83.15 ? 134 PHE B CG 1 ATOM 4068 C CD1 . PHE B 1 138 ? 7.553 -18.812 -22.106 1.00 86.36 ? 134 PHE B CD1 1 ATOM 4069 C CD2 . PHE B 1 138 ? 8.097 -19.261 -24.379 1.00 85.75 ? 134 PHE B CD2 1 ATOM 4070 C CE1 . PHE B 1 138 ? 6.789 -19.960 -22.060 1.00 84.42 ? 134 PHE B CE1 1 ATOM 4071 C CE2 . PHE B 1 138 ? 7.334 -20.413 -24.337 1.00 83.51 ? 134 PHE B CE2 1 ATOM 4072 C CZ . PHE B 1 138 ? 6.681 -20.762 -23.175 1.00 80.85 ? 134 PHE B CZ 1 ATOM 4073 N N . VAL B 1 139 ? 9.667 -14.774 -24.839 1.00 77.03 ? 135 VAL B N 1 ATOM 4074 C CA . VAL B 1 139 ? 10.623 -13.763 -25.285 1.00 81.67 ? 135 VAL B CA 1 ATOM 4075 C C . VAL B 1 139 ? 10.042 -12.350 -25.273 1.00 85.48 ? 135 VAL B C 1 ATOM 4076 O O . VAL B 1 139 ? 8.872 -12.144 -25.598 1.00 89.50 ? 135 VAL B O 1 ATOM 4077 C CB . VAL B 1 139 ? 11.132 -14.074 -26.714 1.00 78.70 ? 135 VAL B CB 1 ATOM 4078 C CG1 . VAL B 1 139 ? 12.052 -12.965 -27.224 1.00 83.31 ? 135 VAL B CG1 1 ATOM 4079 C CG2 . VAL B 1 139 ? 11.849 -15.417 -26.742 1.00 84.12 ? 135 VAL B CG2 1 ATOM 4080 N N . PHE B 1 140 ? 10.874 -11.386 -24.887 1.00 76.94 ? 136 PHE B N 1 ATOM 4081 C CA . PHE B 1 140 ? 10.518 -9.973 -24.958 1.00 78.61 ? 136 PHE B CA 1 ATOM 4082 C C . PHE B 1 140 ? 11.721 -9.148 -25.405 1.00 85.00 ? 136 PHE B C 1 ATOM 4083 O O . PHE B 1 140 ? 12.847 -9.644 -25.435 1.00 91.43 ? 136 PHE B O 1 ATOM 4084 C CB . PHE B 1 140 ? 10.000 -9.469 -23.607 1.00 88.79 ? 136 PHE B CB 1 ATOM 4085 C CG . PHE B 1 140 ? 11.023 -9.520 -22.501 1.00 86.53 ? 136 PHE B CG 1 ATOM 4086 C CD1 . PHE B 1 140 ? 11.975 -8.523 -22.369 1.00 85.63 ? 136 PHE B CD1 1 ATOM 4087 C CD2 . PHE B 1 140 ? 11.021 -10.557 -21.584 1.00 91.00 ? 136 PHE B CD2 1 ATOM 4088 C CE1 . PHE B 1 140 ? 12.911 -8.566 -21.354 1.00 89.24 ? 136 PHE B CE1 1 ATOM 4089 C CE2 . PHE B 1 140 ? 11.956 -10.602 -20.563 1.00 87.39 ? 136 PHE B CE2 1 ATOM 4090 C CZ . PHE B 1 140 ? 12.900 -9.605 -20.450 1.00 87.00 ? 136 PHE B CZ 1 ATOM 4091 N N . VAL B 1 141 ? 11.471 -7.887 -25.748 1.00 90.51 ? 137 VAL B N 1 ATOM 4092 C CA . VAL B 1 141 ? 12.519 -6.989 -26.224 1.00 90.02 ? 137 VAL B CA 1 ATOM 4093 C C . VAL B 1 141 ? 13.045 -6.119 -25.085 1.00 97.33 ? 137 VAL B C 1 ATOM 4094 O O . VAL B 1 141 ? 12.329 -5.264 -24.562 1.00 93.50 ? 137 VAL B O 1 ATOM 4095 C CB . VAL B 1 141 ? 12.004 -6.088 -27.364 1.00 81.57 ? 137 VAL B CB 1 ATOM 4096 C CG1 . VAL B 1 141 ? 13.124 -5.203 -27.904 1.00 83.69 ? 137 VAL B CG1 1 ATOM 4097 C CG2 . VAL B 1 141 ? 11.405 -6.938 -28.478 1.00 73.17 ? 137 VAL B CG2 1 ATOM 4098 N N . ASP B 1 142 ? 14.298 -6.350 -24.706 1.00 106.83 ? 138 ASP B N 1 ATOM 4099 C CA . ASP B 1 142 ? 14.929 -5.593 -23.630 1.00 108.01 ? 138 ASP B CA 1 ATOM 4100 C C . ASP B 1 142 ? 15.450 -4.239 -24.112 1.00 100.33 ? 138 ASP B C 1 ATOM 4101 O O . ASP B 1 142 ? 15.345 -3.239 -23.400 1.00 112.72 ? 138 ASP B O 1 ATOM 4102 C CB . ASP B 1 142 ? 16.074 -6.400 -23.012 1.00 118.71 ? 138 ASP B CB 1 ATOM 4103 C CG . ASP B 1 142 ? 16.676 -5.723 -21.794 1.00 122.49 ? 138 ASP B CG 1 ATOM 4104 O OD1 . ASP B 1 142 ? 15.967 -4.929 -21.139 1.00 123.76 ? 138 ASP B OD1 1 ATOM 4105 O OD2 . ASP B 1 142 ? 17.857 -5.989 -21.487 1.00 127.58 ? 138 ASP B OD2 1 ATOM 4106 N N . LEU B 1 143 ? 16.013 -4.210 -25.318 1.00 88.60 ? 139 LEU B N 1 ATOM 4107 C CA . LEU B 1 143 ? 16.606 -2.987 -25.849 1.00 94.99 ? 139 LEU B CA 1 ATOM 4108 C C . LEU B 1 143 ? 16.523 -2.909 -27.370 1.00 96.67 ? 139 LEU B C 1 ATOM 4109 O O . LEU B 1 143 ? 16.402 -3.926 -28.056 1.00 95.27 ? 139 LEU B O 1 ATOM 4110 C CB . LEU B 1 143 ? 18.069 -2.871 -25.403 1.00 100.69 ? 139 LEU B CB 1 ATOM 4111 C CG . LEU B 1 143 ? 19.014 -4.018 -25.776 1.00 118.68 ? 139 LEU B CG 1 ATOM 4112 C CD1 . LEU B 1 143 ? 19.661 -3.796 -27.141 1.00 105.17 ? 139 LEU B CD1 1 ATOM 4113 C CD2 . LEU B 1 143 ? 20.079 -4.203 -24.702 1.00 125.23 ? 139 LEU B CD2 1 ATOM 4114 N N . TRP B 1 144 ? 16.589 -1.681 -27.875 1.00 94.18 ? 140 TRP B N 1 ATOM 4115 C CA . TRP B 1 144 ? 16.603 -1.402 -29.306 1.00 90.85 ? 140 TRP B CA 1 ATOM 4116 C C . TRP B 1 144 ? 17.927 -0.741 -29.669 1.00 92.12 ? 140 TRP B C 1 ATOM 4117 O O . TRP B 1 144 ? 18.540 -0.076 -28.834 1.00 99.64 ? 140 TRP B O 1 ATOM 4118 C CB . TRP B 1 144 ? 15.429 -0.500 -29.693 1.00 88.37 ? 140 TRP B CB 1 ATOM 4119 C CG . TRP B 1 144 ? 14.228 -1.248 -30.191 1.00 80.81 ? 140 TRP B CG 1 ATOM 4120 C CD1 . TRP B 1 144 ? 13.299 -1.905 -29.439 1.00 81.14 ? 140 TRP B CD1 1 ATOM 4121 C CD2 . TRP B 1 144 ? 13.826 -1.409 -31.555 1.00 81.92 ? 140 TRP B CD2 1 ATOM 4122 N NE1 . TRP B 1 144 ? 12.345 -2.469 -30.251 1.00 70.97 ? 140 TRP B NE1 1 ATOM 4123 C CE2 . TRP B 1 144 ? 12.645 -2.177 -31.555 1.00 72.12 ? 140 TRP B CE2 1 ATOM 4124 C CE3 . TRP B 1 144 ? 14.349 -0.979 -32.777 1.00 90.47 ? 140 TRP B CE3 1 ATOM 4125 C CZ2 . TRP B 1 144 ? 11.983 -2.526 -32.729 1.00 76.70 ? 140 TRP B CZ2 1 ATOM 4126 C CZ3 . TRP B 1 144 ? 13.689 -1.325 -33.939 1.00 82.51 ? 140 TRP B CZ3 1 ATOM 4127 C CH2 . TRP B 1 144 ? 12.519 -2.090 -33.907 1.00 73.31 ? 140 TRP B CH2 1 ATOM 4128 N N . LEU B 1 145 ? 18.365 -0.918 -30.912 1.00 84.00 ? 141 LEU B N 1 ATOM 4129 C CA . LEU B 1 145 ? 19.641 -0.362 -31.348 1.00 80.08 ? 141 LEU B CA 1 ATOM 4130 C C . LEU B 1 145 ? 19.597 0.078 -32.808 1.00 82.31 ? 141 LEU B C 1 ATOM 4131 O O . LEU B 1 145 ? 18.824 -0.455 -33.605 1.00 93.14 ? 141 LEU B O 1 ATOM 4132 C CB . LEU B 1 145 ? 20.760 -1.387 -31.141 1.00 87.78 ? 141 LEU B CB 1 ATOM 4133 C CG . LEU B 1 145 ? 22.176 -0.912 -31.471 1.00 98.94 ? 141 LEU B CG 1 ATOM 4134 C CD1 . LEU B 1 145 ? 22.575 0.254 -30.581 1.00 105.29 ? 141 LEU B CD1 1 ATOM 4135 C CD2 . LEU B 1 145 ? 23.165 -2.052 -31.334 1.00 99.12 ? 141 LEU B CD2 1 ATOM 4136 N N . ASP B 1 146 ? 20.432 1.059 -33.140 1.00 80.45 ? 142 ASP B N 1 ATOM 4137 C CA . ASP B 1 146 ? 20.534 1.577 -34.501 1.00 81.10 ? 142 ASP B CA 1 ATOM 4138 C C . ASP B 1 146 ? 21.980 1.530 -34.994 1.00 95.57 ? 142 ASP B C 1 ATOM 4139 O O . ASP B 1 146 ? 22.863 1.014 -34.309 1.00 101.28 ? 142 ASP B O 1 ATOM 4140 C CB . ASP B 1 146 ? 19.998 3.009 -34.570 1.00 84.03 ? 142 ASP B CB 1 ATOM 4141 C CG . ASP B 1 146 ? 20.826 3.983 -33.757 1.00 98.45 ? 142 ASP B CG 1 ATOM 4142 O OD1 . ASP B 1 146 ? 21.521 3.539 -32.818 1.00 96.41 ? 142 ASP B OD1 1 ATOM 4143 O OD2 . ASP B 1 146 ? 20.777 5.195 -34.055 1.00 100.59 ? 142 ASP B OD2 1 ATOM 4144 N N . SER B 1 147 ? 22.210 2.073 -36.186 1.00 89.13 ? 143 SER B N 1 ATOM 4145 C CA . SER B 1 147 ? 23.526 2.036 -36.817 1.00 89.38 ? 143 SER B CA 1 ATOM 4146 C C . SER B 1 147 ? 24.559 2.892 -36.081 1.00 99.32 ? 143 SER B C 1 ATOM 4147 O O . SER B 1 147 ? 25.763 2.675 -36.222 1.00 107.33 ? 143 SER B O 1 ATOM 4148 C CB . SER B 1 147 ? 23.418 2.497 -38.273 1.00 82.14 ? 143 SER B CB 1 ATOM 4149 O OG . SER B 1 147 ? 22.501 1.697 -38.997 1.00 86.99 ? 143 SER B OG 1 ATOM 4150 N N . GLU B 1 148 ? 24.087 3.859 -35.299 1.00 99.20 ? 144 GLU B N 1 ATOM 4151 C CA . GLU B 1 148 ? 24.976 4.808 -34.631 1.00 92.12 ? 144 GLU B CA 1 ATOM 4152 C C . GLU B 1 148 ? 25.462 4.284 -33.280 1.00 90.74 ? 144 GLU B C 1 ATOM 4153 O O . GLU B 1 148 ? 26.392 4.839 -32.692 1.00 101.96 ? 144 GLU B O 1 ATOM 4154 C CB . GLU B 1 148 ? 24.272 6.156 -34.435 1.00 101.23 ? 144 GLU B CB 1 ATOM 4155 C CG . GLU B 1 148 ? 23.420 6.624 -35.616 1.00 105.96 ? 144 GLU B CG 1 ATOM 4156 C CD . GLU B 1 148 ? 24.239 6.977 -36.845 1.00 128.96 ? 144 GLU B CD 1 ATOM 4157 O OE1 . GLU B 1 148 ? 25.480 6.843 -36.803 1.00 127.96 ? 144 GLU B OE1 1 ATOM 4158 O OE2 . GLU B 1 148 ? 23.636 7.397 -37.856 1.00 103.52 ? 144 GLU B OE2 1 ATOM 4159 N N . GLY B 1 149 ? 24.837 3.214 -32.795 1.00 89.13 ? 145 GLY B N 1 ATOM 4160 C CA . GLY B 1 149 ? 25.200 2.630 -31.516 1.00 91.91 ? 145 GLY B CA 1 ATOM 4161 C C . GLY B 1 149 ? 24.366 3.159 -30.363 1.00 102.67 ? 145 GLY B C 1 ATOM 4162 O O . GLY B 1 149 ? 24.771 3.054 -29.206 1.00 106.70 ? 145 GLY B O 1 ATOM 4163 N N . ARG B 1 150 ? 23.197 3.718 -30.672 1.00 100.30 ? 146 ARG B N 1 ATOM 4164 C CA . ARG B 1 150 ? 22.346 4.322 -29.648 1.00 93.21 ? 146 ARG B CA 1 ATOM 4165 C C . ARG B 1 150 ? 21.547 3.268 -28.890 1.00 95.04 ? 146 ARG B C 1 ATOM 4166 O O . ARG B 1 150 ? 20.715 2.570 -29.468 1.00 98.18 ? 146 ARG B O 1 ATOM 4167 C CB . ARG B 1 150 ? 21.389 5.340 -30.274 1.00 79.19 ? 146 ARG B CB 1 ATOM 4168 C CG . ARG B 1 150 ? 22.076 6.414 -31.092 1.00 102.08 ? 146 ARG B CG 1 ATOM 4169 C CD . ARG B 1 150 ? 23.007 7.249 -30.232 1.00 106.72 ? 146 ARG B CD 1 ATOM 4170 N NE . ARG B 1 150 ? 23.586 8.362 -30.978 1.00 108.06 ? 146 ARG B NE 1 ATOM 4171 C CZ . ARG B 1 150 ? 24.436 9.246 -30.466 1.00 121.11 ? 146 ARG B CZ 1 ATOM 4172 N NH1 . ARG B 1 150 ? 24.816 9.156 -29.198 1.00 117.74 ? 146 ARG B NH1 1 ATOM 4173 N NH2 . ARG B 1 150 ? 24.909 10.224 -31.225 1.00 124.39 ? 146 ARG B NH2 1 ATOM 4174 N N . ASN B 1 151 ? 21.787 3.187 -27.586 1.00 105.94 ? 147 ASN B N 1 ATOM 4175 C CA . ASN B 1 151 ? 21.114 2.217 -26.733 1.00 105.30 ? 147 ASN B CA 1 ATOM 4176 C C . ASN B 1 151 ? 19.840 2.795 -26.138 1.00 107.02 ? 147 ASN B C 1 ATOM 4177 O O . ASN B 1 151 ? 19.895 3.751 -25.362 1.00 104.06 ? 147 ASN B O 1 ATOM 4178 C CB . ASN B 1 151 ? 22.045 1.761 -25.609 1.00 105.71 ? 147 ASN B CB 1 ATOM 4179 C CG . ASN B 1 151 ? 23.302 1.092 -26.126 1.00 111.45 ? 147 ASN B CG 1 ATOM 4180 O OD1 . ASN B 1 151 ? 23.595 1.135 -27.321 1.00 109.55 ? 147 ASN B OD1 1 ATOM 4181 N ND2 . ASN B 1 151 ? 24.056 0.472 -25.226 1.00 111.45 ? 147 ASN B ND2 1 ATOM 4182 N N . TYR B 1 152 ? 18.695 2.220 -26.496 1.00 105.90 ? 148 TYR B N 1 ATOM 4183 C CA . TYR B 1 152 ? 17.435 2.653 -25.910 1.00 104.52 ? 148 TYR B CA 1 ATOM 4184 C C . TYR B 1 152 ? 17.114 1.746 -24.731 1.00 107.43 ? 148 TYR B C 1 ATOM 4185 O O . TYR B 1 152 ? 17.783 0.732 -24.526 1.00 119.52 ? 148 TYR B O 1 ATOM 4186 C CB . TYR B 1 152 ? 16.317 2.620 -26.953 1.00 97.15 ? 148 TYR B CB 1 ATOM 4187 C CG . TYR B 1 152 ? 16.687 3.290 -28.261 1.00 93.62 ? 148 TYR B CG 1 ATOM 4188 C CD1 . TYR B 1 152 ? 17.631 4.307 -28.302 1.00 96.86 ? 148 TYR B CD1 1 ATOM 4189 C CD2 . TYR B 1 152 ? 16.097 2.900 -29.455 1.00 99.79 ? 148 TYR B CD2 1 ATOM 4190 C CE1 . TYR B 1 152 ? 17.976 4.917 -29.492 1.00 107.05 ? 148 TYR B CE1 1 ATOM 4191 C CE2 . TYR B 1 152 ? 16.435 3.507 -30.652 1.00 93.12 ? 148 TYR B CE2 1 ATOM 4192 C CZ . TYR B 1 152 ? 17.375 4.515 -30.664 1.00 92.83 ? 148 TYR B CZ 1 ATOM 4193 O OH . TYR B 1 152 ? 17.717 5.124 -31.850 1.00 78.18 ? 148 TYR B OH 1 ATOM 4194 N N . TYR B 1 153 ? 16.080 2.097 -23.973 1.00 115.17 ? 149 TYR B N 1 ATOM 4195 C CA . TYR B 1 153 ? 15.784 1.404 -22.724 1.00 120.18 ? 149 TYR B CA 1 ATOM 4196 C C . TYR B 1 153 ? 14.283 1.434 -22.405 1.00 116.79 ? 149 TYR B C 1 ATOM 4197 O O . TYR B 1 153 ? 13.566 2.304 -22.899 1.00 120.48 ? 149 TYR B O 1 ATOM 4198 C CB . TYR B 1 153 ? 16.631 2.014 -21.601 1.00 128.84 ? 149 TYR B CB 1 ATOM 4199 C CG . TYR B 1 153 ? 18.072 1.535 -21.653 1.00 119.80 ? 149 TYR B CG 1 ATOM 4200 C CD1 . TYR B 1 153 ? 18.418 0.261 -21.218 1.00 116.26 ? 149 TYR B CD1 1 ATOM 4201 C CD2 . TYR B 1 153 ? 19.080 2.344 -22.165 1.00 116.86 ? 149 TYR B CD2 1 ATOM 4202 C CE1 . TYR B 1 153 ? 19.728 -0.187 -21.277 1.00 123.85 ? 149 TYR B CE1 1 ATOM 4203 C CE2 . TYR B 1 153 ? 20.391 1.904 -22.227 1.00 118.03 ? 149 TYR B CE2 1 ATOM 4204 C CZ . TYR B 1 153 ? 20.710 0.639 -21.782 1.00 133.79 ? 149 TYR B CZ 1 ATOM 4205 O OH . TYR B 1 153 ? 22.013 0.199 -21.843 1.00 138.22 ? 149 TYR B OH 1 ATOM 4206 N N . PRO B 1 154 ? 13.805 0.477 -21.583 1.00 111.23 ? 150 PRO B N 1 ATOM 4207 C CA . PRO B 1 154 ? 12.367 0.247 -21.363 1.00 122.70 ? 150 PRO B CA 1 ATOM 4208 C C . PRO B 1 154 ? 11.525 1.477 -21.014 1.00 130.63 ? 150 PRO B C 1 ATOM 4209 O O . PRO B 1 154 ? 10.441 1.617 -21.579 1.00 122.30 ? 150 PRO B O 1 ATOM 4210 C CB . PRO B 1 154 ? 12.350 -0.745 -20.186 1.00 114.48 ? 150 PRO B CB 1 ATOM 4211 C CG . PRO B 1 154 ? 13.741 -0.734 -19.625 1.00 112.23 ? 150 PRO B CG 1 ATOM 4212 C CD . PRO B 1 154 ? 14.613 -0.467 -20.794 1.00 106.71 ? 150 PRO B CD 1 ATOM 4213 N N . ASN B 1 155 ? 11.999 2.337 -20.115 1.00 129.53 ? 151 ASN B N 1 ATOM 4214 C CA . ASN B 1 155 ? 11.216 3.493 -19.669 1.00 128.68 ? 151 ASN B CA 1 ATOM 4215 C C . ASN B 1 155 ? 9.821 3.083 -19.190 1.00 131.20 ? 151 ASN B C 1 ATOM 4216 O O . ASN B 1 155 ? 8.838 3.784 -19.435 1.00 127.70 ? 151 ASN B O 1 ATOM 4217 C CB . ASN B 1 155 ? 11.098 4.530 -20.794 1.00 122.32 ? 151 ASN B CB 1 ATOM 4218 C CG . ASN B 1 155 ? 12.406 5.242 -21.073 1.00 119.87 ? 151 ASN B CG 1 ATOM 4219 O OD1 . ASN B 1 155 ? 13.013 5.061 -22.129 1.00 117.87 ? 151 ASN B OD1 1 ATOM 4220 N ND2 . ASN B 1 155 ? 12.840 6.069 -20.131 1.00 118.59 ? 151 ASN B ND2 1 ATOM 4221 N N . ASN B 1 156 ? 9.749 1.943 -18.507 1.00 127.07 ? 152 ASN B N 1 ATOM 4222 C CA . ASN B 1 156 ? 8.479 1.387 -18.047 1.00 132.58 ? 152 ASN B CA 1 ATOM 4223 C C . ASN B 1 156 ? 7.491 1.207 -19.196 1.00 123.31 ? 152 ASN B C 1 ATOM 4224 O O . ASN B 1 156 ? 7.863 0.763 -20.283 1.00 110.56 ? 152 ASN B O 1 ATOM 4225 C CB . ASN B 1 156 ? 7.858 2.275 -16.965 1.00 131.27 ? 152 ASN B CB 1 ATOM 4226 C CG . ASN B 1 156 ? 8.682 2.306 -15.693 1.00 127.19 ? 152 ASN B CG 1 ATOM 4227 O OD1 . ASN B 1 156 ? 9.911 2.254 -15.735 1.00 122.09 ? 152 ASN B OD1 1 ATOM 4228 N ND2 . ASN B 1 156 ? 8.006 2.384 -14.552 1.00 140.49 ? 152 ASN B ND2 1 ATOM 4229 N N . ASP B 1 161 ? 14.882 13.419 -25.987 1.00 107.18 ? 157 ASP B N 1 ATOM 4230 C CA . ASP B 1 161 ? 14.726 12.514 -24.854 1.00 126.30 ? 157 ASP B CA 1 ATOM 4231 C C . ASP B 1 161 ? 13.291 12.005 -24.764 1.00 108.01 ? 157 ASP B C 1 ATOM 4232 O O . ASP B 1 161 ? 13.058 10.806 -24.605 1.00 92.64 ? 157 ASP B O 1 ATOM 4233 C CB . ASP B 1 161 ? 15.124 13.215 -23.554 1.00 135.15 ? 157 ASP B CB 1 ATOM 4234 C CG . ASP B 1 161 ? 16.564 13.693 -23.567 1.00 130.87 ? 157 ASP B CG 1 ATOM 4235 O OD1 . ASP B 1 161 ? 17.087 13.984 -24.663 1.00 125.78 ? 157 ASP B OD1 1 ATOM 4236 O OD2 . ASP B 1 161 ? 17.174 13.778 -22.480 1.00 138.95 ? 157 ASP B OD2 1 ATOM 4237 N N . GLY B 1 162 ? 12.335 12.924 -24.867 1.00 112.93 ? 158 GLY B N 1 ATOM 4238 C CA . GLY B 1 162 ? 10.927 12.570 -24.872 1.00 115.65 ? 158 GLY B CA 1 ATOM 4239 C C . GLY B 1 162 ? 10.441 12.241 -26.272 1.00 111.70 ? 158 GLY B C 1 ATOM 4240 O O . GLY B 1 162 ? 9.238 12.132 -26.514 1.00 91.75 ? 158 GLY B O 1 ATOM 4241 N N . LYS B 1 163 ? 11.389 12.088 -27.194 1.00 112.33 ? 159 LYS B N 1 ATOM 4242 C CA . LYS B 1 163 ? 11.089 11.761 -28.583 1.00 104.42 ? 159 LYS B CA 1 ATOM 4243 C C . LYS B 1 163 ? 11.166 10.254 -28.801 1.00 93.69 ? 159 LYS B C 1 ATOM 4244 O O . LYS B 1 163 ? 10.163 9.607 -29.105 1.00 89.82 ? 159 LYS B O 1 ATOM 4245 C CB . LYS B 1 163 ? 12.058 12.487 -29.518 1.00 83.04 ? 159 LYS B CB 1 ATOM 4246 C CG . LYS B 1 163 ? 11.928 12.104 -30.982 1.00 72.57 ? 159 LYS B CG 1 ATOM 4247 C CD . LYS B 1 163 ? 12.660 13.096 -31.866 1.00 70.99 ? 159 LYS B CD 1 ATOM 4248 C CE . LYS B 1 163 ? 12.776 12.599 -33.295 1.00 79.03 ? 159 LYS B CE 1 ATOM 4249 N NZ . LYS B 1 163 ? 13.079 13.705 -34.241 1.00 83.65 ? 159 LYS B NZ 1 ATOM 4250 N N . TYR B 1 164 ? 12.367 9.703 -28.643 1.00 90.88 ? 160 TYR B N 1 ATOM 4251 C CA . TYR B 1 164 ? 12.572 8.262 -28.738 1.00 87.36 ? 160 TYR B CA 1 ATOM 4252 C C . TYR B 1 164 ? 12.140 7.591 -27.443 1.00 93.74 ? 160 TYR B C 1 ATOM 4253 O O . TYR B 1 164 ? 12.673 7.890 -26.374 1.00 104.64 ? 160 TYR B O 1 ATOM 4254 C CB . TYR B 1 164 ? 14.039 7.940 -29.028 1.00 78.53 ? 160 TYR B CB 1 ATOM 4255 C CG . TYR B 1 164 ? 14.491 8.323 -30.418 1.00 80.53 ? 160 TYR B CG 1 ATOM 4256 C CD1 . TYR B 1 164 ? 14.660 9.654 -30.771 1.00 86.04 ? 160 TYR B CD1 1 ATOM 4257 C CD2 . TYR B 1 164 ? 14.757 7.354 -31.375 1.00 81.20 ? 160 TYR B CD2 1 ATOM 4258 C CE1 . TYR B 1 164 ? 15.074 10.009 -32.039 1.00 90.62 ? 160 TYR B CE1 1 ATOM 4259 C CE2 . TYR B 1 164 ? 15.173 7.700 -32.646 1.00 88.64 ? 160 TYR B CE2 1 ATOM 4260 C CZ . TYR B 1 164 ? 15.329 9.029 -32.972 1.00 98.07 ? 160 TYR B CZ 1 ATOM 4261 O OH . TYR B 1 164 ? 15.744 9.380 -34.235 1.00 105.47 ? 160 TYR B OH 1 ATOM 4262 N N . LEU B 1 165 ? 11.175 6.684 -27.545 1.00 88.90 ? 161 LEU B N 1 ATOM 4263 C CA . LEU B 1 165 ? 10.665 5.980 -26.376 1.00 89.14 ? 161 LEU B CA 1 ATOM 4264 C C . LEU B 1 165 ? 10.316 4.536 -26.705 1.00 85.73 ? 161 LEU B C 1 ATOM 4265 O O . LEU B 1 165 ? 9.702 4.250 -27.732 1.00 83.77 ? 161 LEU B O 1 ATOM 4266 C CB . LEU B 1 165 ? 9.435 6.700 -25.816 1.00 91.21 ? 161 LEU B CB 1 ATOM 4267 C CG . LEU B 1 165 ? 8.647 5.966 -24.726 1.00 89.38 ? 161 LEU B CG 1 ATOM 4268 C CD1 . LEU B 1 165 ? 9.512 5.711 -23.495 1.00 107.17 ? 161 LEU B CD1 1 ATOM 4269 C CD2 . LEU B 1 165 ? 7.398 6.750 -24.358 1.00 67.68 ? 161 LEU B CD2 1 ATOM 4270 N N . VAL B 1 166 ? 10.715 3.632 -25.817 1.00 84.59 ? 162 VAL B N 1 ATOM 4271 C CA . VAL B 1 166 ? 10.285 2.242 -25.880 1.00 86.99 ? 162 VAL B CA 1 ATOM 4272 C C . VAL B 1 166 ? 9.191 2.057 -24.837 1.00 86.86 ? 162 VAL B C 1 ATOM 4273 O O . VAL B 1 166 ? 9.226 2.683 -23.779 1.00 95.20 ? 162 VAL B O 1 ATOM 4274 C CB . VAL B 1 166 ? 11.448 1.263 -25.631 1.00 93.10 ? 162 VAL B CB 1 ATOM 4275 C CG1 . VAL B 1 166 ? 10.951 -0.182 -25.651 1.00 100.07 ? 162 VAL B CG1 1 ATOM 4276 C CG2 . VAL B 1 166 ? 12.540 1.472 -26.674 1.00 85.17 ? 162 VAL B CG2 1 ATOM 4277 N N . LEU B 1 167 ? 8.213 1.212 -25.145 1.00 86.55 ? 163 LEU B N 1 ATOM 4278 C CA . LEU B 1 167 ? 7.031 1.072 -24.305 1.00 87.03 ? 163 LEU B CA 1 ATOM 4279 C C . LEU B 1 167 ? 7.127 -0.158 -23.398 1.00 92.44 ? 163 LEU B C 1 ATOM 4280 O O . LEU B 1 167 ? 8.066 -0.945 -23.522 1.00 103.90 ? 163 LEU B O 1 ATOM 4281 C CB . LEU B 1 167 ? 5.798 1.000 -25.206 1.00 91.84 ? 163 LEU B CB 1 ATOM 4282 C CG . LEU B 1 167 ? 5.572 2.259 -26.050 1.00 81.09 ? 163 LEU B CG 1 ATOM 4283 C CD1 . LEU B 1 167 ? 4.429 2.050 -27.027 1.00 75.72 ? 163 LEU B CD1 1 ATOM 4284 C CD2 . LEU B 1 167 ? 5.307 3.479 -25.168 1.00 88.29 ? 163 LEU B CD2 1 ATOM 4285 N N . PRO B 1 168 ? 6.155 -0.333 -22.483 1.00 93.03 ? 164 PRO B N 1 ATOM 4286 C CA . PRO B 1 168 ? 6.176 -1.536 -21.640 1.00 108.03 ? 164 PRO B CA 1 ATOM 4287 C C . PRO B 1 168 ? 5.896 -2.819 -22.422 1.00 109.95 ? 164 PRO B C 1 ATOM 4288 O O . PRO B 1 168 ? 6.273 -3.903 -21.972 1.00 104.54 ? 164 PRO B O 1 ATOM 4289 C CB . PRO B 1 168 ? 5.070 -1.267 -20.609 1.00 101.65 ? 164 PRO B CB 1 ATOM 4290 C CG . PRO B 1 168 ? 4.242 -0.165 -21.191 1.00 97.97 ? 164 PRO B CG 1 ATOM 4291 C CD . PRO B 1 168 ? 5.194 0.663 -21.979 1.00 89.28 ? 164 PRO B CD 1 ATOM 4292 N N . SER B 1 169 ? 5.248 -2.690 -23.575 1.00 103.95 ? 165 SER B N 1 ATOM 4293 C CA . SER B 1 169 ? 4.964 -3.837 -24.432 1.00 99.87 ? 165 SER B CA 1 ATOM 4294 C C . SER B 1 169 ? 6.141 -4.117 -25.372 1.00 97.28 ? 165 SER B C 1 ATOM 4295 O O . SER B 1 169 ? 6.165 -5.138 -26.062 1.00 99.21 ? 165 SER B O 1 ATOM 4296 C CB . SER B 1 169 ? 3.675 -3.601 -25.223 1.00 100.59 ? 165 SER B CB 1 ATOM 4297 O OG . SER B 1 169 ? 3.684 -2.336 -25.855 1.00 104.90 ? 165 SER B OG 1 ATOM 4298 N N . GLY B 1 170 ? 7.110 -3.203 -25.391 1.00 91.52 ? 166 GLY B N 1 ATOM 4299 C CA . GLY B 1 170 ? 8.405 -3.455 -26.004 1.00 94.22 ? 166 GLY B CA 1 ATOM 4300 C C . GLY B 1 170 ? 8.702 -2.760 -27.323 1.00 93.24 ? 166 GLY B C 1 ATOM 4301 O O . GLY B 1 170 ? 9.861 -2.697 -27.733 1.00 95.18 ? 166 GLY B O 1 ATOM 4302 N N . GLU B 1 171 ? 7.681 -2.229 -27.989 1.00 94.40 ? 167 GLU B N 1 ATOM 4303 C CA . GLU B 1 171 ? 7.896 -1.571 -29.280 1.00 92.98 ? 167 GLU B CA 1 ATOM 4304 C C . GLU B 1 171 ? 8.532 -0.195 -29.100 1.00 83.38 ? 167 GLU B C 1 ATOM 4305 O O . GLU B 1 171 ? 8.444 0.407 -28.029 1.00 82.98 ? 167 GLU B O 1 ATOM 4306 C CB . GLU B 1 171 ? 6.588 -1.439 -30.072 1.00 92.19 ? 167 GLU B CB 1 ATOM 4307 C CG . GLU B 1 171 ? 5.481 -0.659 -29.379 1.00 89.74 ? 167 GLU B CG 1 ATOM 4308 C CD . GLU B 1 171 ? 4.629 -1.520 -28.467 1.00 94.07 ? 167 GLU B CD 1 ATOM 4309 O OE1 . GLU B 1 171 ? 4.990 -2.693 -28.234 1.00 111.98 ? 167 GLU B OE1 1 ATOM 4310 O OE2 . GLU B 1 171 ? 3.593 -1.021 -27.979 1.00 100.52 ? 167 GLU B OE2 1 ATOM 4311 N N . LEU B 1 172 ? 9.168 0.291 -30.162 1.00 78.00 ? 168 LEU B N 1 ATOM 4312 C CA . LEU B 1 172 ? 9.851 1.582 -30.148 1.00 76.57 ? 168 LEU B CA 1 ATOM 4313 C C . LEU B 1 172 ? 8.999 2.654 -30.818 1.00 70.58 ? 168 LEU B C 1 ATOM 4314 O O . LEU B 1 172 ? 8.548 2.478 -31.950 1.00 75.74 ? 168 LEU B O 1 ATOM 4315 C CB . LEU B 1 172 ? 11.205 1.473 -30.852 1.00 90.07 ? 168 LEU B CB 1 ATOM 4316 C CG . LEU B 1 172 ? 12.020 2.760 -30.995 1.00 79.11 ? 168 LEU B CG 1 ATOM 4317 C CD1 . LEU B 1 172 ? 12.560 3.225 -29.646 1.00 74.65 ? 168 LEU B CD1 1 ATOM 4318 C CD2 . LEU B 1 172 ? 13.147 2.550 -31.994 1.00 72.59 ? 168 LEU B CD2 1 ATOM 4319 N N . HIS B 1 173 ? 8.793 3.766 -30.119 1.00 70.69 ? 169 HIS B N 1 ATOM 4320 C CA . HIS B 1 173 ? 7.992 4.866 -30.642 1.00 78.16 ? 169 HIS B CA 1 ATOM 4321 C C . HIS B 1 173 ? 8.863 6.058 -31.026 1.00 77.09 ? 169 HIS B C 1 ATOM 4322 O O . HIS B 1 173 ? 9.782 6.431 -30.296 1.00 70.56 ? 169 HIS B O 1 ATOM 4323 C CB . HIS B 1 173 ? 6.943 5.304 -29.619 1.00 84.92 ? 169 HIS B CB 1 ATOM 4324 C CG . HIS B 1 173 ? 6.092 6.442 -30.086 1.00 93.80 ? 169 HIS B CG 1 ATOM 4325 N ND1 . HIS B 1 173 ? 6.473 7.760 -29.953 1.00 100.48 ? 169 HIS B ND1 1 ATOM 4326 C CD2 . HIS B 1 173 ? 4.885 6.460 -30.699 1.00 83.48 ? 169 HIS B CD2 1 ATOM 4327 C CE1 . HIS B 1 173 ? 5.535 8.540 -30.460 1.00 92.74 ? 169 HIS B CE1 1 ATOM 4328 N NE2 . HIS B 1 173 ? 4.560 7.776 -30.917 1.00 88.49 ? 169 HIS B NE2 1 ATOM 4329 N N . ILE B 1 174 ? 8.559 6.645 -32.180 1.00 79.04 ? 170 ILE B N 1 ATOM 4330 C CA . ILE B 1 174 ? 9.225 7.854 -32.653 1.00 80.16 ? 170 ILE B CA 1 ATOM 4331 C C . ILE B 1 174 ? 8.173 8.910 -32.967 1.00 83.56 ? 170 ILE B C 1 ATOM 4332 O O . ILE B 1 174 ? 7.128 8.595 -33.535 1.00 83.48 ? 170 ILE B O 1 ATOM 4333 C CB . ILE B 1 174 ? 10.082 7.583 -33.913 1.00 74.68 ? 170 ILE B CB 1 ATOM 4334 C CG1 . ILE B 1 174 ? 11.267 6.678 -33.564 1.00 65.52 ? 170 ILE B CG1 1 ATOM 4335 C CG2 . ILE B 1 174 ? 10.576 8.898 -34.533 1.00 87.64 ? 170 ILE B CG2 1 ATOM 4336 C CD1 . ILE B 1 174 ? 12.052 6.189 -34.772 1.00 63.41 ? 170 ILE B CD1 1 ATOM 4337 N N . ARG B 1 175 ? 8.453 10.156 -32.594 1.00 86.88 ? 171 ARG B N 1 ATOM 4338 C CA . ARG B 1 175 ? 7.571 11.277 -32.909 1.00 87.26 ? 171 ARG B CA 1 ATOM 4339 C C . ARG B 1 175 ? 8.297 12.274 -33.801 1.00 89.66 ? 171 ARG B C 1 ATOM 4340 O O . ARG B 1 175 ? 9.525 12.351 -33.770 1.00 87.60 ? 171 ARG B O 1 ATOM 4341 C CB . ARG B 1 175 ? 7.084 11.971 -31.633 1.00 87.31 ? 171 ARG B CB 1 ATOM 4342 C CG . ARG B 1 175 ? 8.121 12.858 -30.945 1.00 95.65 ? 171 ARG B CG 1 ATOM 4343 C CD . ARG B 1 175 ? 7.466 13.805 -29.961 1.00 96.72 ? 171 ARG B CD 1 ATOM 4344 N NE . ARG B 1 175 ? 7.039 13.130 -28.739 1.00 99.11 ? 171 ARG B NE 1 ATOM 4345 C CZ . ARG B 1 175 ? 6.252 13.679 -27.820 1.00 109.25 ? 171 ARG B CZ 1 ATOM 4346 N NH1 . ARG B 1 175 ? 5.791 14.911 -27.985 1.00 105.84 ? 171 ARG B NH1 1 ATOM 4347 N NH2 . ARG B 1 175 ? 5.917 12.993 -26.737 1.00 114.40 ? 171 ARG B NH2 1 ATOM 4348 N N . GLU B 1 176 ? 7.536 13.049 -34.572 1.00 88.35 ? 172 GLU B N 1 ATOM 4349 C CA . GLU B 1 176 ? 8.114 14.050 -35.464 1.00 100.03 ? 172 GLU B CA 1 ATOM 4350 C C . GLU B 1 176 ? 9.212 13.424 -36.319 1.00 102.56 ? 172 GLU B C 1 ATOM 4351 O O . GLU B 1 176 ? 10.357 13.880 -36.309 1.00 119.78 ? 172 GLU B O 1 ATOM 4352 C CB . GLU B 1 176 ? 8.665 15.241 -34.664 1.00 110.86 ? 172 GLU B CB 1 ATOM 4353 C CG . GLU B 1 176 ? 7.657 16.346 -34.417 1.00 107.29 ? 172 GLU B CG 1 ATOM 4354 C CD . GLU B 1 176 ? 8.296 17.722 -34.459 1.00 103.25 ? 172 GLU B CD 1 ATOM 4355 O OE1 . GLU B 1 176 ? 9.194 17.989 -33.633 1.00 110.87 ? 172 GLU B OE1 1 ATOM 4356 O OE2 . GLU B 1 176 ? 7.908 18.531 -35.328 1.00 94.32 ? 172 GLU B OE2 1 ATOM 4357 N N . VAL B 1 177 ? 8.866 12.355 -37.032 1.00 84.28 ? 173 VAL B N 1 ATOM 4358 C CA . VAL B 1 177 ? 9.851 11.640 -37.833 1.00 91.72 ? 173 VAL B CA 1 ATOM 4359 C C . VAL B 1 177 ? 10.506 12.609 -38.810 1.00 90.88 ? 173 VAL B C 1 ATOM 4360 O O . VAL B 1 177 ? 9.827 13.237 -39.623 1.00 77.77 ? 173 VAL B O 1 ATOM 4361 C CB . VAL B 1 177 ? 9.203 10.468 -38.605 1.00 77.56 ? 173 VAL B CB 1 ATOM 4362 C CG1 . VAL B 1 177 ? 10.206 9.810 -39.553 1.00 78.81 ? 173 VAL B CG1 1 ATOM 4363 C CG2 . VAL B 1 177 ? 8.635 9.447 -37.627 1.00 78.13 ? 173 VAL B CG2 1 ATOM 4364 N N . GLY B 1 178 ? 11.827 12.729 -38.710 1.00 85.27 ? 174 GLY B N 1 ATOM 4365 C CA . GLY B 1 178 ? 12.601 13.597 -39.580 1.00 88.91 ? 174 GLY B CA 1 ATOM 4366 C C . GLY B 1 178 ? 13.443 12.802 -40.557 1.00 88.00 ? 174 GLY B C 1 ATOM 4367 O O . GLY B 1 178 ? 13.488 11.577 -40.477 1.00 90.38 ? 174 GLY B O 1 ATOM 4368 N N . PRO B 1 179 ? 14.142 13.499 -41.467 1.00 92.66 ? 175 PRO B N 1 ATOM 4369 C CA . PRO B 1 179 ? 15.048 12.857 -42.426 1.00 87.15 ? 175 PRO B CA 1 ATOM 4370 C C . PRO B 1 179 ? 16.259 12.251 -41.726 1.00 80.34 ? 175 PRO B C 1 ATOM 4371 O O . PRO B 1 179 ? 16.917 11.365 -42.271 1.00 85.01 ? 175 PRO B O 1 ATOM 4372 C CB . PRO B 1 179 ? 15.457 14.008 -43.346 1.00 79.26 ? 175 PRO B CB 1 ATOM 4373 C CG . PRO B 1 179 ? 15.347 15.226 -42.485 1.00 78.59 ? 175 PRO B CG 1 ATOM 4374 C CD . PRO B 1 179 ? 14.191 14.968 -41.557 1.00 94.38 ? 175 PRO B CD 1 ATOM 4375 N N . GLU B 1 180 ? 16.538 12.739 -40.521 1.00 77.90 ? 176 GLU B N 1 ATOM 4376 C CA . GLU B 1 180 ? 17.648 12.246 -39.716 1.00 78.79 ? 176 GLU B CA 1 ATOM 4377 C C . GLU B 1 180 ? 17.395 10.821 -39.236 1.00 86.43 ? 176 GLU B C 1 ATOM 4378 O O . GLU B 1 180 ? 18.329 10.041 -39.050 1.00 100.57 ? 176 GLU B O 1 ATOM 4379 C CB . GLU B 1 180 ? 17.885 13.173 -38.517 1.00 88.44 ? 176 GLU B CB 1 ATOM 4380 C CG . GLU B 1 180 ? 16.668 13.361 -37.616 1.00 88.77 ? 176 GLU B CG 1 ATOM 4381 C CD . GLU B 1 180 ? 16.906 14.368 -36.504 1.00 117.82 ? 176 GLU B CD 1 ATOM 4382 O OE1 . GLU B 1 180 ? 18.082 14.668 -36.207 1.00 134.18 ? 176 GLU B OE1 1 ATOM 4383 O OE2 . GLU B 1 180 ? 15.914 14.862 -35.927 1.00 117.43 ? 176 GLU B OE2 1 ATOM 4384 N N . ASP B 1 181 ? 16.122 10.493 -39.040 1.00 84.75 ? 177 ASP B N 1 ATOM 4385 C CA . ASP B 1 181 ? 15.723 9.197 -38.501 1.00 86.72 ? 177 ASP B CA 1 ATOM 4386 C C . ASP B 1 181 ? 15.712 8.083 -39.550 1.00 78.78 ? 177 ASP B C 1 ATOM 4387 O O . ASP B 1 181 ? 16.090 6.948 -39.262 1.00 82.89 ? 177 ASP B O 1 ATOM 4388 C CB . ASP B 1 181 ? 14.335 9.307 -37.862 1.00 81.59 ? 177 ASP B CB 1 ATOM 4389 C CG . ASP B 1 181 ? 14.287 10.323 -36.738 1.00 83.66 ? 177 ASP B CG 1 ATOM 4390 O OD1 . ASP B 1 181 ? 15.319 10.518 -36.062 1.00 99.47 ? 177 ASP B OD1 1 ATOM 4391 O OD2 . ASP B 1 181 ? 13.214 10.927 -36.527 1.00 82.95 ? 177 ASP B OD2 1 ATOM 4392 N N . GLY B 1 182 ? 15.281 8.413 -40.763 1.00 79.67 ? 178 GLY B N 1 ATOM 4393 C CA . GLY B 1 182 ? 14.943 7.405 -41.755 1.00 87.09 ? 178 GLY B CA 1 ATOM 4394 C C . GLY B 1 182 ? 16.097 6.654 -42.392 1.00 89.95 ? 178 GLY B C 1 ATOM 4395 O O . GLY B 1 182 ? 15.990 5.452 -42.646 1.00 88.38 ? 178 GLY B O 1 ATOM 4396 N N . TYR B 1 183 ? 17.203 7.347 -42.644 1.00 83.39 ? 179 TYR B N 1 ATOM 4397 C CA . TYR B 1 183 ? 18.301 6.769 -43.413 1.00 81.87 ? 179 TYR B CA 1 ATOM 4398 C C . TYR B 1 183 ? 19.257 5.994 -42.511 1.00 76.09 ? 179 TYR B C 1 ATOM 4399 O O . TYR B 1 183 ? 20.295 5.507 -42.960 1.00 73.77 ? 179 TYR B O 1 ATOM 4400 C CB . TYR B 1 183 ? 19.044 7.862 -44.183 1.00 65.49 ? 179 TYR B CB 1 ATOM 4401 C CG . TYR B 1 183 ? 18.227 8.461 -45.309 1.00 67.43 ? 179 TYR B CG 1 ATOM 4402 C CD1 . TYR B 1 183 ? 17.072 9.180 -45.043 1.00 74.76 ? 179 TYR B CD1 1 ATOM 4403 C CD2 . TYR B 1 183 ? 18.609 8.303 -46.635 1.00 62.40 ? 179 TYR B CD2 1 ATOM 4404 C CE1 . TYR B 1 183 ? 16.316 9.724 -46.064 1.00 72.24 ? 179 TYR B CE1 1 ATOM 4405 C CE2 . TYR B 1 183 ? 17.860 8.847 -47.663 1.00 65.83 ? 179 TYR B CE2 1 ATOM 4406 C CZ . TYR B 1 183 ? 16.715 9.556 -47.372 1.00 75.07 ? 179 TYR B CZ 1 ATOM 4407 O OH . TYR B 1 183 ? 15.967 10.098 -48.392 1.00 75.44 ? 179 TYR B OH 1 ATOM 4408 N N . LYS B 1 184 ? 18.892 5.878 -41.238 1.00 79.23 ? 180 LYS B N 1 ATOM 4409 C CA . LYS B 1 184 ? 19.547 4.938 -40.338 1.00 76.23 ? 180 LYS B CA 1 ATOM 4410 C C . LYS B 1 184 ? 19.061 3.530 -40.648 1.00 75.63 ? 180 LYS B C 1 ATOM 4411 O O . LYS B 1 184 ? 18.375 3.299 -41.644 1.00 70.98 ? 180 LYS B O 1 ATOM 4412 C CB . LYS B 1 184 ? 19.246 5.253 -38.873 1.00 73.32 ? 180 LYS B CB 1 ATOM 4413 C CG . LYS B 1 184 ? 19.526 6.666 -38.423 1.00 78.85 ? 180 LYS B CG 1 ATOM 4414 C CD . LYS B 1 184 ? 19.138 6.800 -36.959 1.00 73.07 ? 180 LYS B CD 1 ATOM 4415 C CE . LYS B 1 184 ? 19.479 8.158 -36.385 1.00 95.58 ? 180 LYS B CE 1 ATOM 4416 N NZ . LYS B 1 184 ? 19.076 8.248 -34.953 1.00 100.24 ? 180 LYS B NZ 1 ATOM 4417 N N . SER B 1 185 ? 19.432 2.592 -39.785 1.00 83.27 ? 181 SER B N 1 ATOM 4418 C CA . SER B 1 185 ? 18.859 1.254 -39.800 1.00 79.26 ? 181 SER B CA 1 ATOM 4419 C C . SER B 1 185 ? 18.650 0.812 -38.357 1.00 76.79 ? 181 SER B C 1 ATOM 4420 O O . SER B 1 185 ? 19.440 1.162 -37.480 1.00 75.52 ? 181 SER B O 1 ATOM 4421 C CB . SER B 1 185 ? 19.763 0.278 -40.550 1.00 88.63 ? 181 SER B CB 1 ATOM 4422 O OG . SER B 1 185 ? 21.049 0.216 -39.961 1.00 101.49 ? 181 SER B OG 1 ATOM 4423 N N . TYR B 1 186 ? 17.584 0.054 -38.117 1.00 86.20 ? 182 TYR B N 1 ATOM 4424 C CA . TYR B 1 186 ? 17.208 -0.344 -36.763 1.00 91.33 ? 182 TYR B CA 1 ATOM 4425 C C . TYR B 1 186 ? 17.165 -1.859 -36.620 1.00 83.45 ? 182 TYR B C 1 ATOM 4426 O O . TYR B 1 186 ? 16.804 -2.573 -37.555 1.00 80.04 ? 182 TYR B O 1 ATOM 4427 C CB . TYR B 1 186 ? 15.843 0.239 -36.389 1.00 89.69 ? 182 TYR B CB 1 ATOM 4428 C CG . TYR B 1 186 ? 15.758 1.746 -36.482 1.00 87.00 ? 182 TYR B CG 1 ATOM 4429 C CD1 . TYR B 1 186 ? 15.607 2.377 -37.708 1.00 87.66 ? 182 TYR B CD1 1 ATOM 4430 C CD2 . TYR B 1 186 ? 15.815 2.537 -35.343 1.00 75.69 ? 182 TYR B CD2 1 ATOM 4431 C CE1 . TYR B 1 186 ? 15.526 3.754 -37.799 1.00 71.97 ? 182 TYR B CE1 1 ATOM 4432 C CE2 . TYR B 1 186 ? 15.733 3.914 -35.424 1.00 77.64 ? 182 TYR B CE2 1 ATOM 4433 C CZ . TYR B 1 186 ? 15.589 4.517 -36.654 1.00 71.73 ? 182 TYR B CZ 1 ATOM 4434 O OH . TYR B 1 186 ? 15.507 5.888 -36.736 1.00 84.82 ? 182 TYR B OH 1 ATOM 4435 N N . GLN B 1 187 ? 17.537 -2.338 -35.439 1.00 77.19 ? 183 GLN B N 1 ATOM 4436 C CA . GLN B 1 187 ? 17.423 -3.749 -35.111 1.00 80.86 ? 183 GLN B CA 1 ATOM 4437 C C . GLN B 1 187 ? 17.221 -3.886 -33.606 1.00 85.18 ? 183 GLN B C 1 ATOM 4438 O O . GLN B 1 187 ? 17.713 -3.062 -32.833 1.00 80.85 ? 183 GLN B O 1 ATOM 4439 C CB . GLN B 1 187 ? 18.663 -4.516 -35.583 1.00 102.79 ? 183 GLN B CB 1 ATOM 4440 C CG . GLN B 1 187 ? 19.786 -4.630 -34.558 1.00 94.91 ? 183 GLN B CG 1 ATOM 4441 C CD . GLN B 1 187 ? 20.979 -5.407 -35.083 1.00 95.41 ? 183 GLN B CD 1 ATOM 4442 O OE1 . GLN B 1 187 ? 21.555 -6.234 -34.376 1.00 96.62 ? 183 GLN B OE1 1 ATOM 4443 N NE2 . GLN B 1 187 ? 21.361 -5.142 -36.327 1.00 96.61 ? 183 GLN B NE2 1 ATOM 4444 N N . CYS B 1 188 ? 16.498 -4.924 -33.196 1.00 81.61 ? 184 CYS B N 1 ATOM 4445 C CA . CYS B 1 188 ? 16.128 -5.102 -31.796 1.00 87.10 ? 184 CYS B CA 1 ATOM 4446 C C . CYS B 1 188 ? 16.786 -6.329 -31.178 1.00 85.52 ? 184 CYS B C 1 ATOM 4447 O O . CYS B 1 188 ? 17.062 -7.313 -31.867 1.00 83.27 ? 184 CYS B O 1 ATOM 4448 C CB . CYS B 1 188 ? 14.610 -5.211 -31.667 1.00 89.84 ? 184 CYS B CB 1 ATOM 4449 S SG . CYS B 1 188 ? 13.880 -6.528 -32.657 1.00 104.75 ? 184 CYS B SG 1 ATOM 4450 N N . ARG B 1 189 ? 17.030 -6.257 -29.871 1.00 87.58 ? 185 ARG B N 1 ATOM 4451 C CA . ARG B 1 189 ? 17.597 -7.373 -29.125 1.00 82.57 ? 185 ARG B CA 1 ATOM 4452 C C . ARG B 1 189 ? 16.514 -8.031 -28.278 1.00 79.89 ? 185 ARG B C 1 ATOM 4453 O O . ARG B 1 189 ? 15.797 -7.354 -27.541 1.00 79.82 ? 185 ARG B O 1 ATOM 4454 C CB . ARG B 1 189 ? 18.754 -6.907 -28.238 1.00 94.18 ? 185 ARG B CB 1 ATOM 4455 C CG . ARG B 1 189 ? 19.524 -8.050 -27.592 1.00 98.84 ? 185 ARG B CG 1 ATOM 4456 C CD . ARG B 1 189 ? 20.544 -7.561 -26.580 1.00 110.21 ? 185 ARG B CD 1 ATOM 4457 N NE . ARG B 1 189 ? 21.742 -7.017 -27.216 1.00 119.96 ? 185 ARG B NE 1 ATOM 4458 C CZ . ARG B 1 189 ? 22.721 -7.757 -27.731 1.00 124.04 ? 185 ARG B CZ 1 ATOM 4459 N NH1 . ARG B 1 189 ? 22.649 -9.083 -27.700 1.00 106.99 ? 185 ARG B NH1 1 ATOM 4460 N NH2 . ARG B 1 189 ? 23.774 -7.173 -28.286 1.00 102.29 ? 185 ARG B NH2 1 ATOM 4461 N N . THR B 1 190 ? 16.408 -9.352 -28.388 1.00 87.84 ? 186 THR B N 1 ATOM 4462 C CA . THR B 1 190 ? 15.378 -10.112 -27.687 1.00 72.07 ? 186 THR B CA 1 ATOM 4463 C C . THR B 1 190 ? 15.979 -11.067 -26.665 1.00 73.44 ? 186 THR B C 1 ATOM 4464 O O . THR B 1 190 ? 16.963 -11.751 -26.951 1.00 88.00 ? 186 THR B O 1 ATOM 4465 C CB . THR B 1 190 ? 14.518 -10.922 -28.670 1.00 81.95 ? 186 THR B CB 1 ATOM 4466 O OG1 . THR B 1 190 ? 15.343 -11.434 -29.725 1.00 68.97 ? 186 THR B OG1 1 ATOM 4467 C CG2 . THR B 1 190 ? 13.422 -10.051 -29.262 1.00 86.89 ? 186 THR B CG2 1 ATOM 4468 N N . LYS B 1 191 ? 15.381 -11.108 -25.477 1.00 63.37 ? 187 LYS B N 1 ATOM 4469 C CA . LYS B 1 191 ? 15.801 -12.038 -24.436 1.00 76.94 ? 187 LYS B CA 1 ATOM 4470 C C . LYS B 1 191 ? 14.680 -13.007 -24.084 1.00 75.97 ? 187 LYS B C 1 ATOM 4471 O O . LYS B 1 191 ? 13.508 -12.635 -24.051 1.00 74.50 ? 187 LYS B O 1 ATOM 4472 C CB . LYS B 1 191 ? 16.247 -11.291 -23.178 1.00 76.34 ? 187 LYS B CB 1 ATOM 4473 C CG . LYS B 1 191 ? 16.941 -12.196 -22.172 1.00 86.36 ? 187 LYS B CG 1 ATOM 4474 C CD . LYS B 1 191 ? 17.184 -11.505 -20.847 1.00 87.59 ? 187 LYS B CD 1 ATOM 4475 C CE . LYS B 1 191 ? 16.060 -11.789 -19.864 1.00 100.66 ? 187 LYS B CE 1 ATOM 4476 N NZ . LYS B 1 191 ? 16.456 -11.458 -18.471 1.00 125.14 ? 187 LYS B NZ 1 ATOM 4477 N N . HIS B 1 192 ? 15.062 -14.250 -23.813 1.00 81.72 ? 188 HIS B N 1 ATOM 4478 C CA . HIS B 1 192 ? 14.115 -15.298 -23.454 1.00 84.28 ? 188 HIS B CA 1 ATOM 4479 C C . HIS B 1 192 ? 13.965 -15.366 -21.936 1.00 84.25 ? 188 HIS B C 1 ATOM 4480 O O . HIS B 1 192 ? 14.952 -15.275 -21.205 1.00 81.07 ? 188 HIS B O 1 ATOM 4481 C CB . HIS B 1 192 ? 14.581 -16.640 -24.014 1.00 79.48 ? 188 HIS B CB 1 ATOM 4482 C CG . HIS B 1 192 ? 13.546 -17.716 -23.944 1.00 79.02 ? 188 HIS B CG 1 ATOM 4483 N ND1 . HIS B 1 192 ? 13.815 -18.977 -23.459 1.00 90.33 ? 188 HIS B ND1 1 ATOM 4484 C CD2 . HIS B 1 192 ? 12.240 -17.720 -24.301 1.00 87.99 ? 188 HIS B CD2 1 ATOM 4485 C CE1 . HIS B 1 192 ? 12.720 -19.712 -23.521 1.00 90.94 ? 188 HIS B CE1 1 ATOM 4486 N NE2 . HIS B 1 192 ? 11.749 -18.973 -24.026 1.00 92.31 ? 188 HIS B NE2 1 ATOM 4487 N N . ARG B 1 193 ? 12.730 -15.521 -21.466 1.00 91.86 ? 189 ARG B N 1 ATOM 4488 C CA . ARG B 1 193 ? 12.437 -15.407 -20.039 1.00 94.83 ? 189 ARG B CA 1 ATOM 4489 C C . ARG B 1 193 ? 12.599 -16.719 -19.262 1.00 97.17 ? 189 ARG B C 1 ATOM 4490 O O . ARG B 1 193 ? 12.660 -16.702 -18.031 1.00 98.86 ? 189 ARG B O 1 ATOM 4491 C CB . ARG B 1 193 ? 11.014 -14.869 -19.851 1.00 91.64 ? 189 ARG B CB 1 ATOM 4492 C CG . ARG B 1 193 ? 10.828 -14.035 -18.590 1.00 104.64 ? 189 ARG B CG 1 ATOM 4493 C CD . ARG B 1 193 ? 9.726 -13.000 -18.758 1.00 105.24 ? 189 ARG B CD 1 ATOM 4494 N NE . ARG B 1 193 ? 9.719 -12.034 -17.662 1.00 100.81 ? 189 ARG B NE 1 ATOM 4495 C CZ . ARG B 1 193 ? 8.999 -10.916 -17.649 1.00 102.80 ? 189 ARG B CZ 1 ATOM 4496 N NH1 . ARG B 1 193 ? 8.218 -10.608 -18.675 1.00 96.90 ? 189 ARG B NH1 1 ATOM 4497 N NH2 . ARG B 1 193 ? 9.063 -10.101 -16.606 1.00 95.96 ? 189 ARG B NH2 1 ATOM 4498 N N . LEU B 1 194 ? 12.671 -17.846 -19.969 1.00 97.21 ? 190 LEU B N 1 ATOM 4499 C CA . LEU B 1 194 ? 12.850 -19.147 -19.318 1.00 87.13 ? 190 LEU B CA 1 ATOM 4500 C C . LEU B 1 194 ? 14.310 -19.597 -19.286 1.00 90.41 ? 190 LEU B C 1 ATOM 4501 O O . LEU B 1 194 ? 14.634 -20.627 -18.691 1.00 93.70 ? 190 LEU B O 1 ATOM 4502 C CB . LEU B 1 194 ? 12.014 -20.217 -20.025 1.00 89.01 ? 190 LEU B CB 1 ATOM 4503 C CG . LEU B 1 194 ? 10.500 -20.020 -20.086 1.00 89.94 ? 190 LEU B CG 1 ATOM 4504 C CD1 . LEU B 1 194 ? 9.859 -21.232 -20.747 1.00 86.65 ? 190 LEU B CD1 1 ATOM 4505 C CD2 . LEU B 1 194 ? 9.915 -19.784 -18.700 1.00 101.94 ? 190 LEU B CD2 1 ATOM 4506 N N . THR B 1 195 ? 15.182 -18.823 -19.926 1.00 88.11 ? 191 THR B N 1 ATOM 4507 C CA . THR B 1 195 ? 16.597 -19.167 -20.043 1.00 84.39 ? 191 THR B CA 1 ATOM 4508 C C . THR B 1 195 ? 17.472 -17.990 -19.625 1.00 86.80 ? 191 THR B C 1 ATOM 4509 O O . THR B 1 195 ? 18.254 -18.090 -18.678 1.00 103.57 ? 191 THR B O 1 ATOM 4510 C CB . THR B 1 195 ? 16.964 -19.592 -21.479 1.00 84.85 ? 191 THR B CB 1 ATOM 4511 O OG1 . THR B 1 195 ? 16.806 -18.480 -22.368 1.00 78.18 ? 191 THR B OG1 1 ATOM 4512 C CG2 . THR B 1 195 ? 16.088 -20.755 -21.941 1.00 86.92 ? 191 THR B CG2 1 ATOM 4513 N N . GLY B 1 196 ? 17.323 -16.877 -20.338 1.00 91.57 ? 192 GLY B N 1 ATOM 4514 C CA . GLY B 1 196 ? 18.212 -15.737 -20.203 1.00 83.10 ? 192 GLY B CA 1 ATOM 4515 C C . GLY B 1 196 ? 19.101 -15.568 -21.423 1.00 76.27 ? 192 GLY B C 1 ATOM 4516 O O . GLY B 1 196 ? 19.965 -14.692 -21.451 1.00 72.31 ? 192 GLY B O 1 ATOM 4517 N N . GLU B 1 197 ? 18.884 -16.404 -22.436 1.00 82.41 ? 193 GLU B N 1 ATOM 4518 C CA . GLU B 1 197 ? 19.625 -16.288 -23.687 1.00 91.08 ? 193 GLU B CA 1 ATOM 4519 C C . GLU B 1 197 ? 19.110 -15.097 -24.486 1.00 91.16 ? 193 GLU B C 1 ATOM 4520 O O . GLU B 1 197 ? 17.932 -15.041 -24.842 1.00 86.81 ? 193 GLU B O 1 ATOM 4521 C CB . GLU B 1 197 ? 19.494 -17.567 -24.522 1.00 90.54 ? 193 GLU B CB 1 ATOM 4522 C CG . GLU B 1 197 ? 19.837 -18.848 -23.776 1.00 90.24 ? 193 GLU B CG 1 ATOM 4523 C CD . GLU B 1 197 ? 21.299 -18.929 -23.387 1.00 89.54 ? 193 GLU B CD 1 ATOM 4524 O OE1 . GLU B 1 197 ? 22.123 -18.219 -24.001 1.00 93.72 ? 193 GLU B OE1 1 ATOM 4525 O OE2 . GLU B 1 197 ? 21.625 -19.705 -22.463 1.00 96.59 ? 193 GLU B OE2 1 ATOM 4526 N N . THR B 1 198 ? 20.001 -14.152 -24.771 1.00 89.15 ? 194 THR B N 1 ATOM 4527 C CA . THR B 1 198 ? 19.654 -12.990 -25.579 1.00 83.58 ? 194 THR B CA 1 ATOM 4528 C C . THR B 1 198 ? 19.958 -13.263 -27.042 1.00 92.86 ? 194 THR B C 1 ATOM 4529 O O . THR B 1 198 ? 20.469 -14.328 -27.391 1.00 102.95 ? 194 THR B O 1 ATOM 4530 C CB . THR B 1 198 ? 20.425 -11.730 -25.142 1.00 90.80 ? 194 THR B CB 1 ATOM 4531 O OG1 . THR B 1 198 ? 21.833 -11.952 -25.288 1.00 111.21 ? 194 THR B OG1 1 ATOM 4532 C CG2 . THR B 1 198 ? 20.110 -11.374 -23.698 1.00 84.58 ? 194 THR B CG2 1 ATOM 4533 N N . ARG B 1 199 ? 19.665 -12.281 -27.889 1.00 91.72 ? 195 ARG B N 1 ATOM 4534 C CA . ARG B 1 199 ? 19.951 -12.375 -29.314 1.00 94.26 ? 195 ARG B CA 1 ATOM 4535 C C . ARG B 1 199 ? 19.587 -11.079 -30.009 1.00 92.90 ? 195 ARG B C 1 ATOM 4536 O O . ARG B 1 199 ? 18.799 -10.289 -29.493 1.00 87.16 ? 195 ARG B O 1 ATOM 4537 C CB . ARG B 1 199 ? 19.179 -13.524 -29.959 1.00 94.09 ? 195 ARG B CB 1 ATOM 4538 C CG . ARG B 1 199 ? 19.867 -14.118 -31.174 1.00 96.23 ? 195 ARG B CG 1 ATOM 4539 C CD . ARG B 1 199 ? 19.305 -15.487 -31.499 1.00 97.60 ? 195 ARG B CD 1 ATOM 4540 N NE . ARG B 1 199 ? 19.379 -16.376 -30.343 1.00 103.86 ? 195 ARG B NE 1 ATOM 4541 C CZ . ARG B 1 199 ? 18.758 -17.546 -30.252 1.00 105.19 ? 195 ARG B CZ 1 ATOM 4542 N NH1 . ARG B 1 199 ? 18.009 -17.983 -31.254 1.00 112.16 ? 195 ARG B NH1 1 ATOM 4543 N NH2 . ARG B 1 199 ? 18.884 -18.280 -29.155 1.00 106.07 ? 195 ARG B NH2 1 ATOM 4544 N N . LEU B 1 200 ? 20.139 -10.891 -31.202 1.00 98.93 ? 196 LEU B N 1 ATOM 4545 C CA . LEU B 1 200 ? 19.926 -9.675 -31.974 1.00 93.70 ? 196 LEU B CA 1 ATOM 4546 C C . LEU B 1 200 ? 19.037 -9.956 -33.173 1.00 91.34 ? 196 LEU B C 1 ATOM 4547 O O . LEU B 1 200 ? 19.026 -11.069 -33.703 1.00 92.48 ? 196 LEU B O 1 ATOM 4548 C CB . LEU B 1 200 ? 21.262 -9.090 -32.434 1.00 95.00 ? 196 LEU B CB 1 ATOM 4549 C CG . LEU B 1 200 ? 22.105 -8.413 -31.352 1.00 103.09 ? 196 LEU B CG 1 ATOM 4550 C CD1 . LEU B 1 200 ? 23.486 -8.092 -31.896 1.00 111.76 ? 196 LEU B CD1 1 ATOM 4551 C CD2 . LEU B 1 200 ? 21.418 -7.151 -30.841 1.00 107.18 ? 196 LEU B CD2 1 ATOM 4552 N N . SER B 1 201 ? 18.282 -8.942 -33.581 1.00 91.90 ? 197 SER B N 1 ATOM 4553 C CA . SER B 1 201 ? 17.373 -9.067 -34.711 1.00 88.93 ? 197 SER B CA 1 ATOM 4554 C C . SER B 1 201 ? 18.098 -9.591 -35.944 1.00 92.92 ? 197 SER B C 1 ATOM 4555 O O . SER B 1 201 ? 19.165 -9.098 -36.310 1.00 89.13 ? 197 SER B O 1 ATOM 4556 C CB . SER B 1 201 ? 16.713 -7.721 -35.015 1.00 85.25 ? 197 SER B CB 1 ATOM 4557 O OG . SER B 1 201 ? 16.098 -7.723 -36.292 1.00 90.34 ? 197 SER B OG 1 ATOM 4558 N N . ALA B 1 202 ? 17.509 -10.610 -36.562 1.00 98.35 ? 198 ALA B N 1 ATOM 4559 C CA . ALA B 1 202 ? 18.072 -11.231 -37.753 1.00 92.97 ? 198 ALA B CA 1 ATOM 4560 C C . ALA B 1 202 ? 18.229 -10.203 -38.864 1.00 91.38 ? 198 ALA B C 1 ATOM 4561 O O . ALA B 1 202 ? 19.302 -10.065 -39.453 1.00 91.63 ? 198 ALA B O 1 ATOM 4562 C CB . ALA B 1 202 ? 17.187 -12.383 -38.215 1.00 86.36 ? 198 ALA B CB 1 ATOM 4563 N N . THR B 1 203 ? 17.147 -9.478 -39.132 1.00 94.66 ? 199 THR B N 1 ATOM 4564 C CA . THR B 1 203 ? 17.130 -8.460 -40.174 1.00 88.82 ? 199 THR B CA 1 ATOM 4565 C C . THR B 1 203 ? 17.278 -7.066 -39.572 1.00 82.43 ? 199 THR B C 1 ATOM 4566 O O . THR B 1 203 ? 17.350 -6.912 -38.352 1.00 77.86 ? 199 THR B O 1 ATOM 4567 C CB . THR B 1 203 ? 15.829 -8.527 -40.995 1.00 96.43 ? 199 THR B CB 1 ATOM 4568 O OG1 . THR B 1 203 ? 14.704 -8.295 -40.138 1.00 84.72 ? 199 THR B OG1 1 ATOM 4569 C CG2 . THR B 1 203 ? 15.689 -9.891 -41.659 1.00 97.36 ? 199 THR B CG2 1 ATOM 4570 N N . LYS B 1 204 ? 17.316 -6.058 -40.438 1.00 83.61 ? 200 LYS B N 1 ATOM 4571 C CA . LYS B 1 204 ? 17.488 -4.673 -40.014 1.00 84.29 ? 200 LYS B CA 1 ATOM 4572 C C . LYS B 1 204 ? 16.359 -3.807 -40.555 1.00 72.95 ? 200 LYS B C 1 ATOM 4573 O O . LYS B 1 204 ? 16.177 -3.691 -41.768 1.00 68.92 ? 200 LYS B O 1 ATOM 4574 C CB . LYS B 1 204 ? 18.842 -4.139 -40.482 1.00 94.13 ? 200 LYS B CB 1 ATOM 4575 C CG . LYS B 1 204 ? 20.029 -4.851 -39.857 1.00 95.90 ? 200 LYS B CG 1 ATOM 4576 C CD . LYS B 1 204 ? 21.339 -4.282 -40.364 1.00 117.64 ? 200 LYS B CD 1 ATOM 4577 C CE . LYS B 1 204 ? 22.528 -4.983 -39.732 1.00 130.81 ? 200 LYS B CE 1 ATOM 4578 N NZ . LYS B 1 204 ? 23.817 -4.440 -40.236 1.00 177.86 ? 200 LYS B NZ 1 ATOM 4579 N N . GLY B 1 205 ? 15.594 -3.210 -39.648 1.00 75.61 ? 201 GLY B N 1 ATOM 4580 C CA . GLY B 1 205 ? 14.472 -2.376 -40.029 1.00 83.50 ? 201 GLY B CA 1 ATOM 4581 C C . GLY B 1 205 ? 14.903 -1.097 -40.718 1.00 75.72 ? 201 GLY B C 1 ATOM 4582 O O . GLY B 1 205 ? 15.708 -0.333 -40.184 1.00 74.99 ? 201 GLY B O 1 ATOM 4583 N N . ARG B 1 206 ? 14.363 -0.871 -41.912 1.00 67.63 ? 202 ARG B N 1 ATOM 4584 C CA . ARG B 1 206 ? 14.598 0.355 -42.664 1.00 63.43 ? 202 ARG B CA 1 ATOM 4585 C C . ARG B 1 206 ? 13.379 1.262 -42.561 1.00 77.89 ? 202 ARG B C 1 ATOM 4586 O O . ARG B 1 206 ? 12.247 0.804 -42.722 1.00 88.46 ? 202 ARG B O 1 ATOM 4587 C CB . ARG B 1 206 ? 14.898 0.042 -44.132 1.00 62.95 ? 202 ARG B CB 1 ATOM 4588 C CG . ARG B 1 206 ? 16.253 -0.610 -44.374 1.00 76.24 ? 202 ARG B CG 1 ATOM 4589 C CD . ARG B 1 206 ? 17.394 0.385 -44.199 1.00 88.41 ? 202 ARG B CD 1 ATOM 4590 N NE . ARG B 1 206 ? 17.275 1.528 -45.104 1.00 91.37 ? 202 ARG B NE 1 ATOM 4591 C CZ . ARG B 1 206 ? 18.110 2.562 -45.121 1.00 75.93 ? 202 ARG B CZ 1 ATOM 4592 N NH1 . ARG B 1 206 ? 19.136 2.609 -44.282 1.00 78.81 ? 202 ARG B NH1 1 ATOM 4593 N NH2 . ARG B 1 206 ? 17.919 3.555 -45.979 1.00 63.98 ? 202 ARG B NH2 1 ATOM 4594 N N . LEU B 1 207 ? 13.611 2.543 -42.289 1.00 79.90 ? 203 LEU B N 1 ATOM 4595 C CA . LEU B 1 207 ? 12.533 3.522 -42.277 1.00 79.07 ? 203 LEU B CA 1 ATOM 4596 C C . LEU B 1 207 ? 12.537 4.319 -43.570 1.00 88.97 ? 203 LEU B C 1 ATOM 4597 O O . LEU B 1 207 ? 13.434 5.125 -43.819 1.00 91.24 ? 203 LEU B O 1 ATOM 4598 C CB . LEU B 1 207 ? 12.654 4.467 -41.080 1.00 69.50 ? 203 LEU B CB 1 ATOM 4599 C CG . LEU B 1 207 ? 12.297 3.928 -39.692 1.00 84.05 ? 203 LEU B CG 1 ATOM 4600 C CD1 . LEU B 1 207 ? 11.892 5.093 -38.802 1.00 79.02 ? 203 LEU B CD1 1 ATOM 4601 C CD2 . LEU B 1 207 ? 11.195 2.868 -39.736 1.00 91.71 ? 203 LEU B CD2 1 ATOM 4602 N N . VAL B 1 208 ? 11.521 4.080 -44.389 1.00 76.65 ? 204 VAL B N 1 ATOM 4603 C CA . VAL B 1 208 ? 11.366 4.794 -45.644 1.00 71.54 ? 204 VAL B CA 1 ATOM 4604 C C . VAL B 1 208 ? 10.591 6.080 -45.398 1.00 81.76 ? 204 VAL B C 1 ATOM 4605 O O . VAL B 1 208 ? 9.438 6.050 -44.966 1.00 85.25 ? 204 VAL B O 1 ATOM 4606 C CB . VAL B 1 208 ? 10.645 3.930 -46.696 1.00 67.73 ? 204 VAL B CB 1 ATOM 4607 C CG1 . VAL B 1 208 ? 10.407 4.723 -47.980 1.00 73.66 ? 204 VAL B CG1 1 ATOM 4608 C CG2 . VAL B 1 208 ? 11.458 2.673 -46.977 1.00 76.42 ? 204 VAL B CG2 1 ATOM 4609 N N . ILE B 1 209 ? 11.239 7.208 -45.672 1.00 79.93 ? 205 ILE B N 1 ATOM 4610 C CA . ILE B 1 209 ? 10.613 8.514 -45.518 1.00 69.41 ? 205 ILE B CA 1 ATOM 4611 C C . ILE B 1 209 ? 10.153 9.016 -46.874 1.00 76.97 ? 205 ILE B C 1 ATOM 4612 O O . ILE B 1 209 ? 10.967 9.309 -47.751 1.00 87.01 ? 205 ILE B O 1 ATOM 4613 C CB . ILE B 1 209 ? 11.572 9.532 -44.881 1.00 79.63 ? 205 ILE B CB 1 ATOM 4614 C CG1 . ILE B 1 209 ? 11.878 9.117 -43.443 1.00 80.89 ? 205 ILE B CG1 1 ATOM 4615 C CG2 . ILE B 1 209 ? 10.969 10.942 -44.909 1.00 79.74 ? 205 ILE B CG2 1 ATOM 4616 C CD1 . ILE B 1 209 ? 12.972 9.918 -42.803 1.00 103.28 ? 205 ILE B CD1 1 ATOM 4617 N N . THR B 1 210 ? 8.839 9.112 -47.033 1.00 73.71 ? 206 THR B N 1 ATOM 4618 C CA . THR B 1 210 ? 8.248 9.560 -48.285 1.00 67.20 ? 206 THR B CA 1 ATOM 4619 C C . THR B 1 210 ? 7.901 11.037 -48.218 1.00 76.22 ? 206 THR B C 1 ATOM 4620 O O . THR B 1 210 ? 7.474 11.546 -47.180 1.00 66.65 ? 206 THR B O 1 ATOM 4621 C CB . THR B 1 210 ? 6.994 8.749 -48.629 1.00 70.28 ? 206 THR B CB 1 ATOM 4622 O OG1 . THR B 1 210 ? 6.103 8.731 -47.507 1.00 71.06 ? 206 THR B OG1 1 ATOM 4623 C CG2 . THR B 1 210 ? 7.385 7.333 -48.986 1.00 72.76 ? 206 THR B CG2 1 ATOM 4624 N N . GLU B 1 211 ? 8.094 11.720 -49.339 1.00 81.03 ? 207 GLU B N 1 ATOM 4625 C CA . GLU B 1 211 ? 7.882 13.155 -49.406 1.00 60.37 ? 207 GLU B CA 1 ATOM 4626 C C . GLU B 1 211 ? 6.388 13.480 -49.471 1.00 50.76 ? 207 GLU B C 1 ATOM 4627 O O . GLU B 1 211 ? 5.724 13.126 -50.445 1.00 52.51 ? 207 GLU B O 1 ATOM 4628 C CB . GLU B 1 211 ? 8.604 13.732 -50.626 1.00 55.03 ? 207 GLU B CB 1 ATOM 4629 C CG . GLU B 1 211 ? 8.982 15.187 -50.477 1.00 53.60 ? 207 GLU B CG 1 ATOM 4630 C CD . GLU B 1 211 ? 10.071 15.398 -49.449 1.00 70.40 ? 207 GLU B CD 1 ATOM 4631 O OE1 . GLU B 1 211 ? 9.741 15.808 -48.319 1.00 73.19 ? 207 GLU B OE1 1 ATOM 4632 O OE2 . GLU B 1 211 ? 11.254 15.154 -49.770 1.00 73.14 ? 207 GLU B OE2 1 ATOM 4633 N N . PRO B 1 212 ? 5.844 14.137 -48.429 1.00 53.58 ? 208 PRO B N 1 ATOM 4634 C CA . PRO B 1 212 ? 4.443 14.553 -48.566 1.00 55.82 ? 208 PRO B CA 1 ATOM 4635 C C . PRO B 1 212 ? 4.267 15.569 -49.686 1.00 54.48 ? 208 PRO B C 1 ATOM 4636 O O . PRO B 1 212 ? 4.976 16.576 -49.711 1.00 56.05 ? 208 PRO B O 1 ATOM 4637 C CB . PRO B 1 212 ? 4.124 15.181 -47.207 1.00 51.95 ? 208 PRO B CB 1 ATOM 4638 C CG . PRO B 1 212 ? 5.453 15.591 -46.652 1.00 50.48 ? 208 PRO B CG 1 ATOM 4639 C CD . PRO B 1 212 ? 6.416 14.548 -47.135 1.00 61.88 ? 208 PRO B CD 1 ATOM 4640 N N . VAL B 1 213 ? 3.337 15.302 -50.597 1.00 51.04 ? 209 VAL B N 1 ATOM 4641 C CA . VAL B 1 213 ? 3.033 16.216 -51.692 1.00 57.22 ? 209 VAL B CA 1 ATOM 4642 C C . VAL B 1 213 ? 1.544 16.522 -51.698 1.00 55.03 ? 209 VAL B C 1 ATOM 4643 O O . VAL B 1 213 ? 1.113 17.602 -51.298 1.00 55.91 ? 209 VAL B O 1 ATOM 4644 C CB . VAL B 1 213 ? 3.450 15.619 -53.049 1.00 50.48 ? 209 VAL B CB 1 ATOM 4645 C CG1 . VAL B 1 213 ? 3.022 16.525 -54.201 1.00 61.42 ? 209 VAL B CG1 1 ATOM 4646 C CG2 . VAL B 1 213 ? 4.954 15.374 -53.077 1.00 55.70 ? 209 VAL B CG2 1 ATOM 4647 N N . GLY B 1 214 ? 0.763 15.545 -52.145 1.00 54.02 ? 210 GLY B N 1 ATOM 4648 C CA . GLY B 1 214 ? -0.678 15.667 -52.152 1.00 42.45 ? 210 GLY B CA 1 ATOM 4649 C C . GLY B 1 214 ? -1.190 15.420 -50.752 1.00 55.41 ? 210 GLY B C 1 ATOM 4650 O O . GLY B 1 214 ? -0.609 14.634 -50.003 1.00 79.26 ? 210 GLY B O 1 ATOM 4651 N N . SER B 1 215 ? -2.274 16.096 -50.393 1.00 52.48 ? 211 SER B N 1 ATOM 4652 C CA . SER B 1 215 ? -2.836 15.960 -49.061 1.00 51.07 ? 211 SER B CA 1 ATOM 4653 C C . SER B 1 215 ? -3.592 14.641 -48.953 1.00 59.52 ? 211 SER B C 1 ATOM 4654 O O . SER B 1 215 ? -4.411 14.314 -49.813 1.00 62.16 ? 211 SER B O 1 ATOM 4655 C CB . SER B 1 215 ? -3.748 17.144 -48.741 1.00 52.96 ? 211 SER B CB 1 ATOM 4656 O OG . SER B 1 215 ? -4.747 17.305 -49.732 1.00 62.09 ? 211 SER B OG 1 ATOM 4657 N N . LYS B 1 216 ? -3.305 13.887 -47.895 1.00 64.83 ? 212 LYS B N 1 ATOM 4658 C CA . LYS B 1 216 ? -3.861 12.552 -47.720 1.00 50.97 ? 212 LYS B CA 1 ATOM 4659 C C . LYS B 1 216 ? -4.727 12.476 -46.476 1.00 58.02 ? 212 LYS B C 1 ATOM 4660 O O . LYS B 1 216 ? -4.346 12.966 -45.412 1.00 58.70 ? 212 LYS B O 1 ATOM 4661 C CB . LYS B 1 216 ? -2.739 11.519 -47.636 1.00 63.80 ? 212 LYS B CB 1 ATOM 4662 C CG . LYS B 1 216 ? -1.944 11.391 -48.914 1.00 74.27 ? 212 LYS B CG 1 ATOM 4663 C CD . LYS B 1 216 ? -0.758 10.473 -48.730 1.00 83.51 ? 212 LYS B CD 1 ATOM 4664 C CE . LYS B 1 216 ? -0.005 10.284 -50.031 1.00 102.77 ? 212 LYS B CE 1 ATOM 4665 N NZ . LYS B 1 216 ? 1.349 9.716 -49.805 1.00 100.19 ? 212 LYS B NZ 1 ATOM 4666 N N . ALA B 1 217 ? -5.896 11.860 -46.615 1.00 56.44 ? 213 ALA B N 1 ATOM 4667 C CA . ALA B 1 217 ? -6.778 11.654 -45.478 1.00 44.63 ? 213 ALA B CA 1 ATOM 4668 C C . ALA B 1 217 ? -6.154 10.608 -44.553 1.00 52.73 ? 213 ALA B C 1 ATOM 4669 O O . ALA B 1 217 ? -5.408 9.746 -45.014 1.00 57.92 ? 213 ALA B O 1 ATOM 4670 C CB . ALA B 1 217 ? -8.160 11.221 -45.942 1.00 54.86 ? 213 ALA B CB 1 ATOM 4671 N N . PRO B 1 218 ? -6.442 10.687 -43.243 1.00 53.88 ? 214 PRO B N 1 ATOM 4672 C CA . PRO B 1 218 ? -5.858 9.741 -42.283 1.00 54.72 ? 214 PRO B CA 1 ATOM 4673 C C . PRO B 1 218 ? -6.212 8.291 -42.584 1.00 62.82 ? 214 PRO B C 1 ATOM 4674 O O . PRO B 1 218 ? -7.379 7.960 -42.798 1.00 69.40 ? 214 PRO B O 1 ATOM 4675 C CB . PRO B 1 218 ? -6.457 10.186 -40.942 1.00 51.70 ? 214 PRO B CB 1 ATOM 4676 C CG . PRO B 1 218 ? -6.815 11.621 -41.147 1.00 63.25 ? 214 PRO B CG 1 ATOM 4677 C CD . PRO B 1 218 ? -7.271 11.700 -42.573 1.00 55.43 ? 214 PRO B CD 1 ATOM 4678 N N . THR B 1 219 ? -5.189 7.443 -42.599 1.00 62.42 ? 215 THR B N 1 ATOM 4679 C CA . THR B 1 219 ? -5.352 6.017 -42.843 1.00 61.52 ? 215 THR B CA 1 ATOM 4680 C C . THR B 1 219 ? -4.617 5.230 -41.772 1.00 54.43 ? 215 THR B C 1 ATOM 4681 O O . THR B 1 219 ? -3.576 5.664 -41.278 1.00 61.49 ? 215 THR B O 1 ATOM 4682 C CB . THR B 1 219 ? -4.823 5.613 -44.228 1.00 47.99 ? 215 THR B CB 1 ATOM 4683 O OG1 . THR B 1 219 ? -3.462 6.041 -44.365 1.00 59.62 ? 215 THR B OG1 1 ATOM 4684 C CG2 . THR B 1 219 ? -5.664 6.248 -45.321 1.00 64.43 ? 215 THR B CG2 1 ATOM 4685 N N . PHE B 1 220 ? -5.167 4.075 -41.414 1.00 51.14 ? 216 PHE B N 1 ATOM 4686 C CA . PHE B 1 220 ? -4.558 3.220 -40.406 1.00 55.84 ? 216 PHE B CA 1 ATOM 4687 C C . PHE B 1 220 ? -3.746 2.103 -41.051 1.00 61.66 ? 216 PHE B C 1 ATOM 4688 O O . PHE B 1 220 ? -3.693 1.982 -42.276 1.00 62.48 ? 216 PHE B O 1 ATOM 4689 C CB . PHE B 1 220 ? -5.632 2.637 -39.485 1.00 51.01 ? 216 PHE B CB 1 ATOM 4690 C CG . PHE B 1 220 ? -6.143 3.613 -38.462 1.00 58.06 ? 216 PHE B CG 1 ATOM 4691 C CD1 . PHE B 1 220 ? -6.965 4.661 -38.833 1.00 60.60 ? 216 PHE B CD1 1 ATOM 4692 C CD2 . PHE B 1 220 ? -5.800 3.479 -37.127 1.00 57.45 ? 216 PHE B CD2 1 ATOM 4693 C CE1 . PHE B 1 220 ? -7.434 5.560 -37.893 1.00 57.15 ? 216 PHE B CE1 1 ATOM 4694 C CE2 . PHE B 1 220 ? -6.267 4.376 -36.182 1.00 54.07 ? 216 PHE B CE2 1 ATOM 4695 C CZ . PHE B 1 220 ? -7.084 5.416 -36.566 1.00 53.43 ? 216 PHE B CZ 1 ATOM 4696 N N . ALA B 1 221 ? -3.111 1.293 -40.210 1.00 60.89 ? 217 ALA B N 1 ATOM 4697 C CA . ALA B 1 221 ? -2.302 0.176 -40.674 1.00 61.26 ? 217 ALA B CA 1 ATOM 4698 C C . ALA B 1 221 ? -3.193 -0.895 -41.287 1.00 66.87 ? 217 ALA B C 1 ATOM 4699 O O . ALA B 1 221 ? -2.885 -1.444 -42.346 1.00 61.29 ? 217 ALA B O 1 ATOM 4700 C CB . ALA B 1 221 ? -1.486 -0.399 -39.525 1.00 68.69 ? 217 ALA B CB 1 ATOM 4701 N N . THR B 1 222 ? -4.304 -1.174 -40.612 1.00 71.41 ? 218 THR B N 1 ATOM 4702 C CA . THR B 1 222 ? -5.251 -2.193 -41.050 1.00 59.05 ? 218 THR B CA 1 ATOM 4703 C C . THR B 1 222 ? -6.656 -1.620 -41.198 1.00 61.84 ? 218 THR B C 1 ATOM 4704 O O . THR B 1 222 ? -6.967 -0.552 -40.668 1.00 58.66 ? 218 THR B O 1 ATOM 4705 C CB . THR B 1 222 ? -5.292 -3.379 -40.069 1.00 63.49 ? 218 THR B CB 1 ATOM 4706 O OG1 . THR B 1 222 ? -5.581 -2.903 -38.749 1.00 67.53 ? 218 THR B OG1 1 ATOM 4707 C CG2 . THR B 1 222 ? -3.957 -4.115 -40.065 1.00 72.48 ? 218 THR B CG2 1 ATOM 4708 N N . ALA B 1 223 ? -7.498 -2.347 -41.925 1.00 69.57 ? 219 ALA B N 1 ATOM 4709 C CA . ALA B 1 223 ? -8.866 -1.921 -42.188 1.00 51.51 ? 219 ALA B CA 1 ATOM 4710 C C . ALA B 1 223 ? -9.765 -2.172 -40.978 1.00 51.09 ? 219 ALA B C 1 ATOM 4711 O O . ALA B 1 223 ? -10.874 -1.643 -40.903 1.00 63.48 ? 219 ALA B O 1 ATOM 4712 C CB . ALA B 1 223 ? -9.411 -2.644 -43.415 1.00 34.10 ? 219 ALA B CB 1 ATOM 4713 N N . SER B 1 224 ? -9.282 -2.975 -40.032 1.00 45.85 ? 220 SER B N 1 ATOM 4714 C CA . SER B 1 224 ? -10.074 -3.337 -38.861 1.00 41.05 ? 220 SER B CA 1 ATOM 4715 C C . SER B 1 224 ? -10.371 -2.114 -38.000 1.00 51.94 ? 220 SER B C 1 ATOM 4716 O O . SER B 1 224 ? -9.474 -1.334 -37.676 1.00 61.78 ? 220 SER B O 1 ATOM 4717 C CB . SER B 1 224 ? -9.353 -4.405 -38.033 1.00 48.15 ? 220 SER B CB 1 ATOM 4718 O OG . SER B 1 224 ? -10.188 -4.900 -36.999 1.00 53.76 ? 220 SER B OG 1 ATOM 4719 N N . LYS B 1 225 ? -11.641 -1.955 -37.640 1.00 63.17 ? 221 LYS B N 1 ATOM 4720 C CA . LYS B 1 225 ? -12.090 -0.817 -36.845 1.00 57.60 ? 221 LYS B CA 1 ATOM 4721 C C . LYS B 1 225 ? -12.085 -1.128 -35.355 1.00 53.38 ? 221 LYS B C 1 ATOM 4722 O O . LYS B 1 225 ? -12.511 -0.302 -34.546 1.00 55.01 ? 221 LYS B O 1 ATOM 4723 C CB . LYS B 1 225 ? -13.494 -0.392 -37.269 1.00 68.62 ? 221 LYS B CB 1 ATOM 4724 C CG . LYS B 1 225 ? -13.574 0.142 -38.679 1.00 90.77 ? 221 LYS B CG 1 ATOM 4725 C CD . LYS B 1 225 ? -15.002 0.490 -39.039 1.00 98.35 ? 221 LYS B CD 1 ATOM 4726 C CE . LYS B 1 225 ? -15.103 1.026 -40.452 1.00 108.86 ? 221 LYS B CE 1 ATOM 4727 N NZ . LYS B 1 225 ? -16.511 1.314 -40.833 1.00 99.46 ? 221 LYS B NZ 1 ATOM 4728 N N . ILE B 1 226 ? -11.615 -2.317 -34.992 1.00 56.95 ? 222 ILE B N 1 ATOM 4729 C CA . ILE B 1 226 ? -11.625 -2.726 -33.594 1.00 59.84 ? 222 ILE B CA 1 ATOM 4730 C C . ILE B 1 226 ? -10.479 -3.662 -33.232 1.00 64.24 ? 222 ILE B C 1 ATOM 4731 O O . ILE B 1 226 ? -9.951 -4.389 -34.074 1.00 71.17 ? 222 ILE B O 1 ATOM 4732 C CB . ILE B 1 226 ? -12.959 -3.412 -33.226 1.00 58.39 ? 222 ILE B CB 1 ATOM 4733 C CG1 . ILE B 1 226 ? -13.082 -3.555 -31.707 1.00 53.24 ? 222 ILE B CG1 1 ATOM 4734 C CG2 . ILE B 1 226 ? -13.083 -4.773 -33.916 1.00 58.49 ? 222 ILE B CG2 1 ATOM 4735 C CD1 . ILE B 1 226 ? -14.510 -3.549 -31.218 1.00 50.60 ? 222 ILE B CD1 1 ATOM 4736 N N . SER B 1 227 ? -10.112 -3.624 -31.957 1.00 63.25 ? 223 SER B N 1 ATOM 4737 C CA . SER B 1 227 ? -9.071 -4.476 -31.409 1.00 70.37 ? 223 SER B CA 1 ATOM 4738 C C . SER B 1 227 ? -9.403 -4.771 -29.953 1.00 64.42 ? 223 SER B C 1 ATOM 4739 O O . SER B 1 227 ? -10.212 -4.069 -29.346 1.00 65.44 ? 223 SER B O 1 ATOM 4740 C CB . SER B 1 227 ? -7.704 -3.801 -31.529 1.00 75.43 ? 223 SER B CB 1 ATOM 4741 O OG . SER B 1 227 ? -7.733 -2.499 -30.971 1.00 81.36 ? 223 SER B OG 1 ATOM 4742 N N . SER B 1 228 ? -8.790 -5.812 -29.399 1.00 59.75 ? 224 SER B N 1 ATOM 4743 C CA . SER B 1 228 ? -8.948 -6.125 -27.984 1.00 63.69 ? 224 SER B CA 1 ATOM 4744 C C . SER B 1 228 ? -7.590 -6.248 -27.323 1.00 67.96 ? 224 SER B C 1 ATOM 4745 O O . SER B 1 228 ? -6.603 -6.617 -27.960 1.00 77.74 ? 224 SER B O 1 ATOM 4746 C CB . SER B 1 228 ? -9.751 -7.411 -27.785 1.00 71.76 ? 224 SER B CB 1 ATOM 4747 O OG . SER B 1 228 ? -9.315 -8.438 -28.655 1.00 87.26 ? 224 SER B OG 1 ATOM 4748 N N . LEU B 1 229 ? -7.553 -5.932 -26.034 1.00 64.31 ? 225 LEU B N 1 ATOM 4749 C CA . LEU B 1 229 ? -6.308 -5.886 -25.291 1.00 68.43 ? 225 LEU B CA 1 ATOM 4750 C C . LEU B 1 229 ? -6.580 -6.110 -23.812 1.00 70.58 ? 225 LEU B C 1 ATOM 4751 O O . LEU B 1 229 ? -7.693 -5.883 -23.340 1.00 65.51 ? 225 LEU B O 1 ATOM 4752 C CB . LEU B 1 229 ? -5.620 -4.540 -25.509 1.00 61.47 ? 225 LEU B CB 1 ATOM 4753 C CG . LEU B 1 229 ? -4.147 -4.458 -25.126 1.00 70.45 ? 225 LEU B CG 1 ATOM 4754 C CD1 . LEU B 1 229 ? -3.296 -5.280 -26.083 1.00 79.49 ? 225 LEU B CD1 1 ATOM 4755 C CD2 . LEU B 1 229 ? -3.710 -3.012 -25.117 1.00 71.26 ? 225 LEU B CD2 1 ATOM 4756 N N . LEU B 1 230 ? -5.571 -6.572 -23.083 1.00 78.64 ? 226 LEU B N 1 ATOM 4757 C CA . LEU B 1 230 ? -5.699 -6.716 -21.641 1.00 78.13 ? 226 LEU B CA 1 ATOM 4758 C C . LEU B 1 230 ? -4.338 -6.784 -20.958 1.00 76.65 ? 226 LEU B C 1 ATOM 4759 O O . LEU B 1 230 ? -3.320 -7.038 -21.602 1.00 75.43 ? 226 LEU B O 1 ATOM 4760 C CB . LEU B 1 230 ? -6.522 -7.959 -21.295 1.00 71.17 ? 226 LEU B CB 1 ATOM 4761 C CG . LEU B 1 230 ? -5.812 -9.311 -21.364 1.00 62.37 ? 226 LEU B CG 1 ATOM 4762 C CD1 . LEU B 1 230 ? -6.775 -10.415 -20.965 1.00 60.21 ? 226 LEU B CD1 1 ATOM 4763 C CD2 . LEU B 1 230 ? -5.232 -9.571 -22.752 1.00 63.43 ? 226 LEU B CD2 1 ATOM 4764 N N . GLY B 1 231 ? -4.332 -6.556 -19.649 1.00 74.25 ? 227 GLY B N 1 ATOM 4765 C CA . GLY B 1 231 ? -3.118 -6.647 -18.861 1.00 80.96 ? 227 GLY B CA 1 ATOM 4766 C C . GLY B 1 231 ? -3.422 -6.793 -17.383 1.00 85.97 ? 227 GLY B C 1 ATOM 4767 O O . GLY B 1 231 ? -4.583 -6.756 -16.974 1.00 89.53 ? 227 GLY B O 1 ATOM 4768 N N . SER B 1 232 ? -2.379 -6.967 -16.578 1.00 91.66 ? 228 SER B N 1 ATOM 4769 C CA . SER B 1 232 ? -2.537 -7.051 -15.131 1.00 98.00 ? 228 SER B CA 1 ATOM 4770 C C . SER B 1 232 ? -2.824 -5.669 -14.552 1.00 106.12 ? 228 SER B C 1 ATOM 4771 O O . SER B 1 232 ? -2.563 -4.652 -15.195 1.00 100.04 ? 228 SER B O 1 ATOM 4772 C CB . SER B 1 232 ? -1.290 -7.658 -14.482 1.00 102.77 ? 228 SER B CB 1 ATOM 4773 O OG . SER B 1 232 ? -0.177 -6.793 -14.590 1.00 109.90 ? 228 SER B OG 1 ATOM 4774 N N . SER B 1 233 ? -3.380 -5.643 -13.345 1.00 106.76 ? 229 SER B N 1 ATOM 4775 C CA . SER B 1 233 ? -3.729 -4.391 -12.679 1.00 102.77 ? 229 SER B CA 1 ATOM 4776 C C . SER B 1 233 ? -2.531 -3.463 -12.542 1.00 104.78 ? 229 SER B C 1 ATOM 4777 O O . SER B 1 233 ? -2.611 -2.280 -12.869 1.00 103.77 ? 229 SER B O 1 ATOM 4778 C CB . SER B 1 233 ? -4.322 -4.677 -11.297 1.00 104.44 ? 229 SER B CB 1 ATOM 4779 O OG . SER B 1 233 ? -5.543 -5.388 -11.403 1.00 106.49 ? 229 SER B OG 1 ATOM 4780 N N . SER B 1 234 ? -1.415 -4.010 -12.078 1.00 110.99 ? 230 SER B N 1 ATOM 4781 C CA . SER B 1 234 ? -0.259 -3.196 -11.732 1.00 108.97 ? 230 SER B CA 1 ATOM 4782 C C . SER B 1 234 ? 0.616 -2.863 -12.943 1.00 108.67 ? 230 SER B C 1 ATOM 4783 O O . SER B 1 234 ? 1.609 -2.147 -12.816 1.00 110.28 ? 230 SER B O 1 ATOM 4784 C CB . SER B 1 234 ? 0.573 -3.909 -10.666 1.00 102.35 ? 230 SER B CB 1 ATOM 4785 O OG . SER B 1 234 ? 1.510 -3.025 -10.081 1.00 109.99 ? 230 SER B OG 1 ATOM 4786 N N . SER B 1 235 ? 0.248 -3.377 -14.113 1.00 102.37 ? 231 SER B N 1 ATOM 4787 C CA . SER B 1 235 ? 1.034 -3.157 -15.326 1.00 98.11 ? 231 SER B CA 1 ATOM 4788 C C . SER B 1 235 ? 0.772 -1.794 -15.955 1.00 91.62 ? 231 SER B C 1 ATOM 4789 O O . SER B 1 235 ? -0.304 -1.217 -15.791 1.00 96.21 ? 231 SER B O 1 ATOM 4790 C CB . SER B 1 235 ? 0.749 -4.254 -16.355 1.00 101.38 ? 231 SER B CB 1 ATOM 4791 O OG . SER B 1 235 ? -0.624 -4.291 -16.699 1.00 96.57 ? 231 SER B OG 1 ATOM 4792 N N . ASP B 1 236 ? 1.771 -1.289 -16.674 1.00 88.58 ? 232 ASP B N 1 ATOM 4793 C CA . ASP B 1 236 ? 1.612 -0.092 -17.488 1.00 95.06 ? 232 ASP B CA 1 ATOM 4794 C C . ASP B 1 236 ? 1.151 -0.516 -18.876 1.00 91.18 ? 232 ASP B C 1 ATOM 4795 O O . ASP B 1 236 ? 1.871 -1.219 -19.585 1.00 89.53 ? 232 ASP B O 1 ATOM 4796 C CB . ASP B 1 236 ? 2.919 0.698 -17.570 1.00 101.48 ? 232 ASP B CB 1 ATOM 4797 C CG . ASP B 1 236 ? 3.383 1.203 -16.217 1.00 103.77 ? 232 ASP B CG 1 ATOM 4798 O OD1 . ASP B 1 236 ? 2.578 1.184 -15.264 1.00 103.28 ? 232 ASP B OD1 1 ATOM 4799 O OD2 . ASP B 1 236 ? 4.552 1.628 -16.108 1.00 105.68 ? 232 ASP B OD2 1 ATOM 4800 N N . ILE B 1 237 ? -0.046 -0.084 -19.259 1.00 85.34 ? 233 ILE B N 1 ATOM 4801 C CA . ILE B 1 237 ? -0.679 -0.574 -20.481 1.00 86.67 ? 233 ILE B CA 1 ATOM 4802 C C . ILE B 1 237 ? -0.619 0.452 -21.605 1.00 72.79 ? 233 ILE B C 1 ATOM 4803 O O . ILE B 1 237 ? -0.751 1.656 -21.382 1.00 68.05 ? 233 ILE B O 1 ATOM 4804 C CB . ILE B 1 237 ? -2.150 -0.966 -20.227 1.00 80.21 ? 233 ILE B CB 1 ATOM 4805 C CG1 . ILE B 1 237 ? -2.220 -2.020 -19.118 1.00 73.94 ? 233 ILE B CG1 1 ATOM 4806 C CG2 . ILE B 1 237 ? -2.799 -1.498 -21.511 1.00 71.82 ? 233 ILE B CG2 1 ATOM 4807 C CD1 . ILE B 1 237 ? -3.622 -2.346 -18.656 1.00 80.20 ? 233 ILE B CD1 1 ATOM 4808 N N . VAL B 1 238 ? -0.423 -0.057 -22.816 1.00 73.44 ? 234 VAL B N 1 ATOM 4809 C CA . VAL B 1 238 ? -0.350 0.761 -24.017 1.00 70.06 ? 234 VAL B CA 1 ATOM 4810 C C . VAL B 1 238 ? -1.591 0.554 -24.869 1.00 71.61 ? 234 VAL B C 1 ATOM 4811 O O . VAL B 1 238 ? -2.152 -0.539 -24.903 1.00 80.41 ? 234 VAL B O 1 ATOM 4812 C CB . VAL B 1 238 ? 0.906 0.420 -24.847 1.00 79.17 ? 234 VAL B CB 1 ATOM 4813 C CG1 . VAL B 1 238 ? 0.846 1.053 -26.245 1.00 81.65 ? 234 VAL B CG1 1 ATOM 4814 C CG2 . VAL B 1 238 ? 2.153 0.859 -24.105 1.00 82.83 ? 234 VAL B CG2 1 ATOM 4815 N N . LEU B 1 239 ? -2.020 1.614 -25.545 1.00 61.49 ? 235 LEU B N 1 ATOM 4816 C CA . LEU B 1 239 ? -3.062 1.512 -26.554 1.00 62.94 ? 235 LEU B CA 1 ATOM 4817 C C . LEU B 1 239 ? -2.565 2.152 -27.842 1.00 61.40 ? 235 LEU B C 1 ATOM 4818 O O . LEU B 1 239 ? -2.355 3.363 -27.912 1.00 64.82 ? 235 LEU B O 1 ATOM 4819 C CB . LEU B 1 239 ? -4.352 2.172 -26.071 1.00 64.44 ? 235 LEU B CB 1 ATOM 4820 C CG . LEU B 1 239 ? -4.974 1.503 -24.841 1.00 64.84 ? 235 LEU B CG 1 ATOM 4821 C CD1 . LEU B 1 239 ? -6.142 2.325 -24.340 1.00 65.16 ? 235 LEU B CD1 1 ATOM 4822 C CD2 . LEU B 1 239 ? -5.409 0.072 -25.149 1.00 74.01 ? 235 LEU B CD2 1 ATOM 4823 N N . LEU B 1 240 ? -2.377 1.322 -28.860 1.00 76.83 ? 236 LEU B N 1 ATOM 4824 C CA . LEU B 1 240 ? -1.800 1.771 -30.117 1.00 73.83 ? 236 LEU B CA 1 ATOM 4825 C C . LEU B 1 240 ? -2.799 2.553 -30.950 1.00 70.80 ? 236 LEU B C 1 ATOM 4826 O O . LEU B 1 240 ? -3.972 2.191 -31.038 1.00 89.09 ? 236 LEU B O 1 ATOM 4827 C CB . LEU B 1 240 ? -1.292 0.578 -30.932 1.00 86.86 ? 236 LEU B CB 1 ATOM 4828 C CG . LEU B 1 240 ? -0.125 -0.220 -30.351 1.00 93.34 ? 236 LEU B CG 1 ATOM 4829 C CD1 . LEU B 1 240 ? 0.108 -1.463 -31.193 1.00 103.50 ? 236 LEU B CD1 1 ATOM 4830 C CD2 . LEU B 1 240 ? 1.138 0.629 -30.282 1.00 81.23 ? 236 LEU B CD2 1 ATOM 4831 N N . CYS B 1 241 ? -2.325 3.641 -31.543 1.00 60.39 ? 237 CYS B N 1 ATOM 4832 C CA . CYS B 1 241 ? -3.024 4.271 -32.649 1.00 68.73 ? 237 CYS B CA 1 ATOM 4833 C C . CYS B 1 241 ? -1.996 4.513 -33.743 1.00 69.05 ? 237 CYS B C 1 ATOM 4834 O O . CYS B 1 241 ? -1.079 5.319 -33.579 1.00 81.48 ? 237 CYS B O 1 ATOM 4835 C CB . CYS B 1 241 ? -3.695 5.577 -32.219 1.00 75.98 ? 237 CYS B CB 1 ATOM 4836 S SG . CYS B 1 241 ? -5.192 5.980 -33.152 1.00 99.52 ? 237 CYS B SG 1 ATOM 4837 N N . GLN B 1 242 ? -2.153 3.804 -34.855 1.00 60.83 ? 238 GLN B N 1 ATOM 4838 C CA . GLN B 1 242 ? -1.253 3.945 -35.988 1.00 63.24 ? 238 GLN B CA 1 ATOM 4839 C C . GLN B 1 242 ? -2.004 4.656 -37.096 1.00 65.04 ? 238 GLN B C 1 ATOM 4840 O O . GLN B 1 242 ? -2.886 4.076 -37.723 1.00 80.67 ? 238 GLN B O 1 ATOM 4841 C CB . GLN B 1 242 ? -0.747 2.579 -36.454 1.00 90.63 ? 238 GLN B CB 1 ATOM 4842 C CG . GLN B 1 242 ? 0.118 1.868 -35.425 1.00 99.97 ? 238 GLN B CG 1 ATOM 4843 C CD . GLN B 1 242 ? 0.366 0.411 -35.769 1.00 94.55 ? 238 GLN B CD 1 ATOM 4844 O OE1 . GLN B 1 242 ? -0.502 -0.267 -36.319 1.00 110.49 ? 238 GLN B OE1 1 ATOM 4845 N NE2 . GLN B 1 242 ? 1.557 -0.079 -35.446 1.00 83.84 ? 238 GLN B NE2 1 ATOM 4846 N N . ALA B 1 243 ? -1.648 5.914 -37.332 1.00 58.93 ? 239 ALA B N 1 ATOM 4847 C CA . ALA B 1 243 ? -2.360 6.738 -38.298 1.00 50.63 ? 239 ALA B CA 1 ATOM 4848 C C . ALA B 1 243 ? -1.396 7.677 -39.008 1.00 56.69 ? 239 ALA B C 1 ATOM 4849 O O . ALA B 1 243 ? -0.511 8.265 -38.385 1.00 69.67 ? 239 ALA B O 1 ATOM 4850 C CB . ALA B 1 243 ? -3.474 7.526 -37.607 1.00 57.64 ? 239 ALA B CB 1 ATOM 4851 N N . GLN B 1 244 ? -1.581 7.811 -40.317 1.00 43.55 ? 240 GLN B N 1 ATOM 4852 C CA . GLN B 1 244 ? -0.729 8.658 -41.140 1.00 45.33 ? 240 GLN B CA 1 ATOM 4853 C C . GLN B 1 244 ? -1.568 9.561 -42.028 1.00 52.23 ? 240 GLN B C 1 ATOM 4854 O O . GLN B 1 244 ? -2.356 9.084 -42.846 1.00 70.57 ? 240 GLN B O 1 ATOM 4855 C CB . GLN B 1 244 ? 0.211 7.807 -41.994 1.00 58.43 ? 240 GLN B CB 1 ATOM 4856 C CG . GLN B 1 244 ? 1.436 7.316 -41.245 1.00 56.95 ? 240 GLN B CG 1 ATOM 4857 C CD . GLN B 1 244 ? 2.388 6.496 -42.104 1.00 66.98 ? 240 GLN B CD 1 ATOM 4858 O OE1 . GLN B 1 244 ? 3.319 5.882 -41.584 1.00 92.68 ? 240 GLN B OE1 1 ATOM 4859 N NE2 . GLN B 1 244 ? 2.166 6.485 -43.417 1.00 58.43 ? 240 GLN B NE2 1 ATOM 4860 N N . ALA B 1 245 ? -1.389 10.868 -41.862 1.00 49.12 ? 241 ALA B N 1 ATOM 4861 C CA . ALA B 1 245 ? -2.132 11.852 -42.640 1.00 50.66 ? 241 ALA B CA 1 ATOM 4862 C C . ALA B 1 245 ? -1.247 13.030 -43.020 1.00 60.55 ? 241 ALA B C 1 ATOM 4863 O O . ALA B 1 245 ? -0.292 13.362 -42.319 1.00 62.91 ? 241 ALA B O 1 ATOM 4864 C CB . ALA B 1 245 ? -3.351 12.340 -41.863 1.00 41.37 ? 241 ALA B CB 1 ATOM 4865 N N . PHE B 1 246 ? -1.572 13.639 -44.154 1.00 61.74 ? 242 PHE B N 1 ATOM 4866 C CA . PHE B 1 246 ? -0.942 14.876 -44.602 1.00 62.31 ? 242 PHE B CA 1 ATOM 4867 C C . PHE B 1 246 ? -2.025 15.901 -44.958 1.00 55.98 ? 242 PHE B C 1 ATOM 4868 O O . PHE B 1 246 ? -2.599 15.826 -46.041 1.00 48.73 ? 242 PHE B O 1 ATOM 4869 C CB . PHE B 1 246 ? -0.016 14.644 -45.796 1.00 60.39 ? 242 PHE B CB 1 ATOM 4870 C CG . PHE B 1 246 ? 0.729 15.881 -46.209 1.00 62.87 ? 242 PHE B CG 1 ATOM 4871 C CD1 . PHE B 1 246 ? 1.581 16.512 -45.318 1.00 50.18 ? 242 PHE B CD1 1 ATOM 4872 C CD2 . PHE B 1 246 ? 0.560 16.429 -47.467 1.00 63.81 ? 242 PHE B CD2 1 ATOM 4873 C CE1 . PHE B 1 246 ? 2.258 17.658 -45.676 1.00 51.55 ? 242 PHE B CE1 1 ATOM 4874 C CE2 . PHE B 1 246 ? 1.239 17.578 -47.833 1.00 65.33 ? 242 PHE B CE2 1 ATOM 4875 C CZ . PHE B 1 246 ? 2.089 18.192 -46.935 1.00 64.54 ? 242 PHE B CZ 1 ATOM 4876 N N . PRO B 1 247 ? -2.333 16.847 -44.048 1.00 60.27 ? 243 PRO B N 1 ATOM 4877 C CA . PRO B 1 247 ? -1.601 17.235 -42.831 1.00 52.66 ? 243 PRO B CA 1 ATOM 4878 C C . PRO B 1 247 ? -1.545 16.188 -41.727 1.00 43.59 ? 243 PRO B C 1 ATOM 4879 O O . PRO B 1 247 ? -2.428 15.337 -41.618 1.00 47.22 ? 243 PRO B O 1 ATOM 4880 C CB . PRO B 1 247 ? -2.375 18.465 -42.335 1.00 54.69 ? 243 PRO B CB 1 ATOM 4881 C CG . PRO B 1 247 ? -3.087 18.987 -43.530 1.00 51.48 ? 243 PRO B CG 1 ATOM 4882 C CD . PRO B 1 247 ? -3.451 17.770 -44.317 1.00 62.43 ? 243 PRO B CD 1 ATOM 4883 N N . VAL B 1 248 ? -0.502 16.276 -40.907 1.00 50.28 ? 244 VAL B N 1 ATOM 4884 C CA . VAL B 1 248 ? -0.348 15.395 -39.758 1.00 55.47 ? 244 VAL B CA 1 ATOM 4885 C C . VAL B 1 248 ? -1.529 15.623 -38.819 1.00 42.98 ? 244 VAL B C 1 ATOM 4886 O O . VAL B 1 248 ? -1.796 16.756 -38.422 1.00 57.37 ? 244 VAL B O 1 ATOM 4887 C CB . VAL B 1 248 ? 0.982 15.645 -39.015 1.00 48.80 ? 244 VAL B CB 1 ATOM 4888 C CG1 . VAL B 1 248 ? 1.154 14.642 -37.875 1.00 42.78 ? 244 VAL B CG1 1 ATOM 4889 C CG2 . VAL B 1 248 ? 2.153 15.560 -39.987 1.00 48.68 ? 244 VAL B CG2 1 ATOM 4890 N N . PRO B 1 249 ? -2.243 14.548 -38.459 1.00 38.51 ? 245 PRO B N 1 ATOM 4891 C CA . PRO B 1 249 ? -3.508 14.737 -37.749 1.00 52.25 ? 245 PRO B CA 1 ATOM 4892 C C . PRO B 1 249 ? -3.319 14.943 -36.252 1.00 56.39 ? 245 PRO B C 1 ATOM 4893 O O . PRO B 1 249 ? -2.183 15.053 -35.787 1.00 56.87 ? 245 PRO B O 1 ATOM 4894 C CB . PRO B 1 249 ? -4.242 13.433 -38.031 1.00 53.76 ? 245 PRO B CB 1 ATOM 4895 C CG . PRO B 1 249 ? -3.130 12.401 -38.055 1.00 46.47 ? 245 PRO B CG 1 ATOM 4896 C CD . PRO B 1 249 ? -1.882 13.121 -38.545 1.00 56.35 ? 245 PRO B CD 1 ATOM 4897 N N . TYR B 1 250 ? -4.425 15.003 -35.517 1.00 59.07 ? 246 TYR B N 1 ATOM 4898 C CA . TYR B 1 250 ? -4.380 15.062 -34.064 1.00 57.88 ? 246 TYR B CA 1 ATOM 4899 C C . TYR B 1 250 ? -5.256 13.947 -33.511 1.00 66.31 ? 246 TYR B C 1 ATOM 4900 O O . TYR B 1 250 ? -6.394 13.756 -33.944 1.00 68.19 ? 246 TYR B O 1 ATOM 4901 C CB . TYR B 1 250 ? -4.830 16.434 -33.548 1.00 63.65 ? 246 TYR B CB 1 ATOM 4902 C CG . TYR B 1 250 ? -6.306 16.726 -33.721 1.00 67.50 ? 246 TYR B CG 1 ATOM 4903 C CD1 . TYR B 1 250 ? -6.790 17.291 -34.892 1.00 63.18 ? 246 TYR B CD1 1 ATOM 4904 C CD2 . TYR B 1 250 ? -7.212 16.446 -32.707 1.00 67.52 ? 246 TYR B CD2 1 ATOM 4905 C CE1 . TYR B 1 250 ? -8.136 17.562 -35.052 1.00 54.67 ? 246 TYR B CE1 1 ATOM 4906 C CE2 . TYR B 1 250 ? -8.559 16.713 -32.858 1.00 71.92 ? 246 TYR B CE2 1 ATOM 4907 C CZ . TYR B 1 250 ? -9.016 17.271 -34.031 1.00 67.20 ? 246 TYR B CZ 1 ATOM 4908 O OH . TYR B 1 250 ? -10.359 17.537 -34.180 1.00 76.58 ? 246 TYR B OH 1 ATOM 4909 N N . THR B 1 251 ? -4.701 13.201 -32.564 1.00 71.04 ? 247 THR B N 1 ATOM 4910 C CA . THR B 1 251 ? -5.368 12.035 -32.002 1.00 61.40 ? 247 THR B CA 1 ATOM 4911 C C . THR B 1 251 ? -5.994 12.376 -30.660 1.00 73.39 ? 247 THR B C 1 ATOM 4912 O O . THR B 1 251 ? -5.308 12.831 -29.745 1.00 81.97 ? 247 THR B O 1 ATOM 4913 C CB . THR B 1 251 ? -4.384 10.871 -31.821 1.00 62.67 ? 247 THR B CB 1 ATOM 4914 O OG1 . THR B 1 251 ? -3.701 10.624 -33.057 1.00 77.17 ? 247 THR B OG1 1 ATOM 4915 C CG2 . THR B 1 251 ? -5.108 9.603 -31.374 1.00 68.23 ? 247 THR B CG2 1 ATOM 4916 N N . ARG B 1 252 ? -7.300 12.153 -30.554 1.00 68.83 ? 248 ARG B N 1 ATOM 4917 C CA . ARG B 1 252 ? -8.023 12.400 -29.314 1.00 75.82 ? 248 ARG B CA 1 ATOM 4918 C C . ARG B 1 252 ? -8.719 11.124 -28.855 1.00 68.08 ? 248 ARG B C 1 ATOM 4919 O O . ARG B 1 252 ? -9.626 10.621 -29.520 1.00 59.20 ? 248 ARG B O 1 ATOM 4920 C CB . ARG B 1 252 ? -9.034 13.534 -29.497 1.00 80.76 ? 248 ARG B CB 1 ATOM 4921 C CG . ARG B 1 252 ? -9.475 14.177 -28.193 1.00 86.56 ? 248 ARG B CG 1 ATOM 4922 C CD . ARG B 1 252 ? -8.354 14.986 -27.552 1.00 85.80 ? 248 ARG B CD 1 ATOM 4923 N NE . ARG B 1 252 ? -8.694 15.409 -26.197 1.00 91.03 ? 248 ARG B NE 1 ATOM 4924 C CZ . ARG B 1 252 ? -8.613 14.626 -25.125 1.00 90.32 ? 248 ARG B CZ 1 ATOM 4925 N NH1 . ARG B 1 252 ? -8.209 13.368 -25.239 1.00 88.22 ? 248 ARG B NH1 1 ATOM 4926 N NH2 . ARG B 1 252 ? -8.943 15.103 -23.934 1.00 82.21 ? 248 ARG B NH2 1 ATOM 4927 N N . TRP B 1 253 ? -8.279 10.607 -27.712 1.00 72.25 ? 249 TRP B N 1 ATOM 4928 C CA . TRP B 1 253 ? -8.796 9.354 -27.172 1.00 60.85 ? 249 TRP B CA 1 ATOM 4929 C C . TRP B 1 253 ? -9.978 9.579 -26.237 1.00 62.64 ? 249 TRP B C 1 ATOM 4930 O O . TRP B 1 253 ? -9.871 10.309 -25.249 1.00 65.76 ? 249 TRP B O 1 ATOM 4931 C CB . TRP B 1 253 ? -7.694 8.600 -26.425 1.00 68.77 ? 249 TRP B CB 1 ATOM 4932 C CG . TRP B 1 253 ? -6.747 7.866 -27.324 1.00 65.27 ? 249 TRP B CG 1 ATOM 4933 C CD1 . TRP B 1 253 ? -5.685 8.389 -28.001 1.00 61.55 ? 249 TRP B CD1 1 ATOM 4934 C CD2 . TRP B 1 253 ? -6.775 6.469 -27.640 1.00 69.06 ? 249 TRP B CD2 1 ATOM 4935 N NE1 . TRP B 1 253 ? -5.052 7.406 -28.721 1.00 68.96 ? 249 TRP B NE1 1 ATOM 4936 C CE2 . TRP B 1 253 ? -5.702 6.218 -28.515 1.00 71.32 ? 249 TRP B CE2 1 ATOM 4937 C CE3 . TRP B 1 253 ? -7.604 5.408 -27.268 1.00 70.15 ? 249 TRP B CE3 1 ATOM 4938 C CZ2 . TRP B 1 253 ? -5.436 4.948 -29.024 1.00 69.01 ? 249 TRP B CZ2 1 ATOM 4939 C CZ3 . TRP B 1 253 ? -7.338 4.151 -27.775 1.00 75.00 ? 249 TRP B CZ3 1 ATOM 4940 C CH2 . TRP B 1 253 ? -6.264 3.932 -28.643 1.00 69.37 ? 249 TRP B CH2 1 ATOM 4941 N N . TYR B 1 254 ? -11.103 8.946 -26.557 1.00 67.93 ? 250 TYR B N 1 ATOM 4942 C CA . TYR B 1 254 ? -12.289 8.993 -25.710 1.00 58.21 ? 250 TYR B CA 1 ATOM 4943 C C . TYR B 1 254 ? -12.479 7.672 -24.982 1.00 55.93 ? 250 TYR B C 1 ATOM 4944 O O . TYR B 1 254 ? -11.675 6.750 -25.125 1.00 61.87 ? 250 TYR B O 1 ATOM 4945 C CB . TYR B 1 254 ? -13.532 9.313 -26.540 1.00 56.21 ? 250 TYR B CB 1 ATOM 4946 C CG . TYR B 1 254 ? -13.409 10.581 -27.352 1.00 62.80 ? 250 TYR B CG 1 ATOM 4947 C CD1 . TYR B 1 254 ? -13.720 11.816 -26.801 1.00 58.46 ? 250 TYR B CD1 1 ATOM 4948 C CD2 . TYR B 1 254 ? -12.979 10.543 -28.669 1.00 65.36 ? 250 TYR B CD2 1 ATOM 4949 C CE1 . TYR B 1 254 ? -13.606 12.977 -27.541 1.00 68.05 ? 250 TYR B CE1 1 ATOM 4950 C CE2 . TYR B 1 254 ? -12.862 11.699 -29.417 1.00 65.42 ? 250 TYR B CE2 1 ATOM 4951 C CZ . TYR B 1 254 ? -13.177 12.913 -28.849 1.00 62.74 ? 250 TYR B CZ 1 ATOM 4952 O OH . TYR B 1 254 ? -13.062 14.067 -29.590 1.00 56.23 ? 250 TYR B OH 1 ATOM 4953 N N . LYS B 1 255 ? -13.545 7.593 -24.195 1.00 57.78 ? 251 LYS B N 1 ATOM 4954 C CA . LYS B 1 255 ? -13.934 6.346 -23.556 1.00 65.66 ? 251 LYS B CA 1 ATOM 4955 C C . LYS B 1 255 ? -15.452 6.252 -23.493 1.00 69.97 ? 251 LYS B C 1 ATOM 4956 O O . LYS B 1 255 ? -16.134 7.239 -23.214 1.00 78.42 ? 251 LYS B O 1 ATOM 4957 C CB . LYS B 1 255 ? -13.332 6.236 -22.154 1.00 70.09 ? 251 LYS B CB 1 ATOM 4958 C CG . LYS B 1 255 ? -13.555 4.879 -21.509 1.00 64.09 ? 251 LYS B CG 1 ATOM 4959 C CD . LYS B 1 255 ? -12.931 4.797 -20.130 1.00 59.17 ? 251 LYS B CD 1 ATOM 4960 C CE . LYS B 1 255 ? -13.088 3.406 -19.537 1.00 54.26 ? 251 LYS B CE 1 ATOM 4961 N NZ . LYS B 1 255 ? -12.411 3.272 -18.219 1.00 67.50 ? 251 LYS B NZ 1 ATOM 4962 N N . PHE B 1 256 ? -15.973 5.060 -23.757 1.00 71.93 ? 252 PHE B N 1 ATOM 4963 C CA . PHE B 1 256 ? -17.411 4.833 -23.752 1.00 68.21 ? 252 PHE B CA 1 ATOM 4964 C C . PHE B 1 256 ? -17.923 4.562 -22.345 1.00 78.44 ? 252 PHE B C 1 ATOM 4965 O O . PHE B 1 256 ? -17.152 4.518 -21.385 1.00 78.26 ? 252 PHE B O 1 ATOM 4966 C CB . PHE B 1 256 ? -17.770 3.655 -24.665 1.00 71.91 ? 252 PHE B CB 1 ATOM 4967 C CG . PHE B 1 256 ? -18.110 4.055 -26.071 1.00 67.45 ? 252 PHE B CG 1 ATOM 4968 C CD1 . PHE B 1 256 ? -19.406 4.399 -26.410 1.00 82.15 ? 252 PHE B CD1 1 ATOM 4969 C CD2 . PHE B 1 256 ? -17.140 4.079 -27.056 1.00 62.47 ? 252 PHE B CD2 1 ATOM 4970 C CE1 . PHE B 1 256 ? -19.728 4.766 -27.701 1.00 85.80 ? 252 PHE B CE1 1 ATOM 4971 C CE2 . PHE B 1 256 ? -17.457 4.445 -28.351 1.00 63.82 ? 252 PHE B CE2 1 ATOM 4972 C CZ . PHE B 1 256 ? -18.753 4.789 -28.672 1.00 75.86 ? 252 PHE B CZ 1 ATOM 4973 N N . ILE B 1 257 ? -19.236 4.392 -22.239 1.00 95.66 ? 253 ILE B N 1 ATOM 4974 C CA . ILE B 1 257 ? -19.868 3.896 -21.026 1.00 96.84 ? 253 ILE B CA 1 ATOM 4975 C C . ILE B 1 257 ? -20.506 2.563 -21.400 1.00 111.51 ? 253 ILE B C 1 ATOM 4976 O O . ILE B 1 257 ? -20.888 2.359 -22.553 1.00 109.93 ? 253 ILE B O 1 ATOM 4977 C CB . ILE B 1 257 ? -20.906 4.890 -20.456 1.00 85.60 ? 253 ILE B CB 1 ATOM 4978 C CG1 . ILE B 1 257 ? -20.212 6.178 -19.999 1.00 81.32 ? 253 ILE B CG1 1 ATOM 4979 C CG2 . ILE B 1 257 ? -21.667 4.275 -19.281 1.00 98.18 ? 253 ILE B CG2 1 ATOM 4980 C CD1 . ILE B 1 257 ? -19.974 7.199 -21.105 1.00 82.33 ? 253 ILE B CD1 1 ATOM 4981 N N . GLU B 1 258 ? -20.607 1.660 -20.431 1.00 117.13 ? 254 GLU B N 1 ATOM 4982 C CA . GLU B 1 258 ? -20.960 0.270 -20.708 1.00 115.37 ? 254 GLU B CA 1 ATOM 4983 C C . GLU B 1 258 ? -22.281 0.128 -21.460 1.00 104.23 ? 254 GLU B C 1 ATOM 4984 O O . GLU B 1 258 ? -23.323 0.596 -21.005 1.00 107.46 ? 254 GLU B O 1 ATOM 4985 C CB . GLU B 1 258 ? -21.032 -0.518 -19.397 1.00 122.45 ? 254 GLU B CB 1 ATOM 4986 C CG . GLU B 1 258 ? -19.754 -0.476 -18.573 1.00 125.35 ? 254 GLU B CG 1 ATOM 4987 C CD . GLU B 1 258 ? -18.580 -1.117 -19.286 1.00 120.90 ? 254 GLU B CD 1 ATOM 4988 O OE1 . GLU B 1 258 ? -18.710 -2.282 -19.719 1.00 121.05 ? 254 GLU B OE1 1 ATOM 4989 O OE2 . GLU B 1 258 ? -17.529 -0.455 -19.417 1.00 119.52 ? 254 GLU B OE2 1 ATOM 4990 N N . GLY B 1 259 ? -22.219 -0.539 -22.610 1.00 107.19 ? 255 GLY B N 1 ATOM 4991 C CA . GLY B 1 259 ? -23.399 -0.850 -23.399 1.00 113.86 ? 255 GLY B CA 1 ATOM 4992 C C . GLY B 1 259 ? -24.206 0.356 -23.847 1.00 113.84 ? 255 GLY B C 1 ATOM 4993 O O . GLY B 1 259 ? -25.406 0.238 -24.099 1.00 113.95 ? 255 GLY B O 1 ATOM 4994 N N . THR B 1 260 ? -23.552 1.511 -23.954 1.00 110.17 ? 256 THR B N 1 ATOM 4995 C CA . THR B 1 260 ? -24.221 2.738 -24.384 1.00 101.86 ? 256 THR B CA 1 ATOM 4996 C C . THR B 1 260 ? -23.427 3.462 -25.465 1.00 98.96 ? 256 THR B C 1 ATOM 4997 O O . THR B 1 260 ? -22.234 3.216 -25.647 1.00 93.61 ? 256 THR B O 1 ATOM 4998 C CB . THR B 1 260 ? -24.444 3.707 -23.205 1.00 99.17 ? 256 THR B CB 1 ATOM 4999 O OG1 . THR B 1 260 ? -23.182 4.059 -22.625 1.00 100.53 ? 256 THR B OG1 1 ATOM 5000 C CG2 . THR B 1 260 ? -25.336 3.074 -22.146 1.00 104.62 ? 256 THR B CG2 1 ATOM 5001 N N . THR B 1 261 ? -24.108 4.353 -26.182 1.00 92.39 ? 257 THR B N 1 ATOM 5002 C CA . THR B 1 261 ? -23.481 5.161 -27.223 1.00 92.31 ? 257 THR B CA 1 ATOM 5003 C C . THR B 1 261 ? -22.893 6.441 -26.635 1.00 91.26 ? 257 THR B C 1 ATOM 5004 O O . THR B 1 261 ? -22.318 7.258 -27.355 1.00 84.92 ? 257 THR B O 1 ATOM 5005 C CB . THR B 1 261 ? -24.487 5.527 -28.337 1.00 95.60 ? 257 THR B CB 1 ATOM 5006 O OG1 . THR B 1 261 ? -23.826 6.287 -29.357 1.00 101.72 ? 257 THR B OG1 1 ATOM 5007 C CG2 . THR B 1 261 ? -25.660 6.332 -27.776 1.00 98.27 ? 257 THR B CG2 1 ATOM 5008 N N . ARG B 1 262 ? -23.040 6.610 -25.323 1.00 98.03 ? 258 ARG B N 1 ATOM 5009 C CA . ARG B 1 262 ? -22.537 7.797 -24.640 1.00 95.98 ? 258 ARG B CA 1 ATOM 5010 C C . ARG B 1 262 ? -21.013 7.800 -24.666 1.00 83.61 ? 258 ARG B C 1 ATOM 5011 O O . ARG B 1 262 ? -20.387 6.742 -24.728 1.00 84.84 ? 258 ARG B O 1 ATOM 5012 C CB . ARG B 1 262 ? -23.048 7.847 -23.199 1.00 95.94 ? 258 ARG B CB 1 ATOM 5013 C CG . ARG B 1 262 ? -24.561 7.741 -23.076 1.00 94.39 ? 258 ARG B CG 1 ATOM 5014 C CD . ARG B 1 262 ? -25.258 9.049 -23.423 1.00 94.76 ? 258 ARG B CD 1 ATOM 5015 N NE . ARG B 1 262 ? -26.603 8.833 -23.951 1.00 110.26 ? 258 ARG B NE 1 ATOM 5016 C CZ . ARG B 1 262 ? -27.615 8.320 -23.255 1.00 117.64 ? 258 ARG B CZ 1 ATOM 5017 N NH1 . ARG B 1 262 ? -27.449 7.953 -21.992 1.00 109.05 ? 258 ARG B NH1 1 ATOM 5018 N NH2 . ARG B 1 262 ? -28.800 8.167 -23.830 1.00 102.77 ? 258 ARG B NH2 1 ATOM 5019 N N . LYS B 1 263 ? -20.421 8.989 -24.610 1.00 78.27 ? 259 LYS B N 1 ATOM 5020 C CA . LYS B 1 263 ? -18.982 9.130 -24.797 1.00 77.49 ? 259 LYS B CA 1 ATOM 5021 C C . LYS B 1 263 ? -18.415 10.301 -24.004 1.00 75.78 ? 259 LYS B C 1 ATOM 5022 O O . LYS B 1 263 ? -19.081 11.320 -23.822 1.00 84.62 ? 259 LYS B O 1 ATOM 5023 C CB . LYS B 1 263 ? -18.673 9.317 -26.283 1.00 69.84 ? 259 LYS B CB 1 ATOM 5024 C CG . LYS B 1 263 ? -17.200 9.249 -26.650 1.00 62.17 ? 259 LYS B CG 1 ATOM 5025 C CD . LYS B 1 263 ? -16.924 10.020 -27.930 1.00 61.97 ? 259 LYS B CD 1 ATOM 5026 C CE . LYS B 1 263 ? -17.746 9.496 -29.095 1.00 47.64 ? 259 LYS B CE 1 ATOM 5027 N NZ . LYS B 1 263 ? -17.447 10.229 -30.352 1.00 40.39 ? 259 LYS B NZ 1 ATOM 5028 N N . GLN B 1 264 ? -17.176 10.147 -23.545 1.00 67.14 ? 260 GLN B N 1 ATOM 5029 C CA . GLN B 1 264 ? -16.458 11.224 -22.872 1.00 80.90 ? 260 GLN B CA 1 ATOM 5030 C C . GLN B 1 264 ? -14.967 11.156 -23.197 1.00 70.82 ? 260 GLN B C 1 ATOM 5031 O O . GLN B 1 264 ? -14.406 10.068 -23.333 1.00 70.80 ? 260 GLN B O 1 ATOM 5032 C CB . GLN B 1 264 ? -16.672 11.158 -21.356 1.00 81.00 ? 260 GLN B CB 1 ATOM 5033 C CG . GLN B 1 264 ? -18.106 11.419 -20.921 1.00 93.59 ? 260 GLN B CG 1 ATOM 5034 C CD . GLN B 1 264 ? -18.203 11.950 -19.503 1.00 95.72 ? 260 GLN B CD 1 ATOM 5035 O OE1 . GLN B 1 264 ? -18.938 12.901 -19.234 1.00 90.00 ? 260 GLN B OE1 1 ATOM 5036 N NE2 . GLN B 1 264 ? -17.463 11.336 -18.587 1.00 93.32 ? 260 GLN B NE2 1 ATOM 5037 N N . ALA B 1 265 ? -14.329 12.318 -23.320 1.00 68.13 ? 261 ALA B N 1 ATOM 5038 C CA . ALA B 1 265 ? -12.887 12.371 -23.541 1.00 67.94 ? 261 ALA B CA 1 ATOM 5039 C C . ALA B 1 265 ? -12.198 11.997 -22.239 1.00 71.29 ? 261 ALA B C 1 ATOM 5040 O O . ALA B 1 265 ? -12.874 11.807 -21.227 1.00 84.81 ? 261 ALA B O 1 ATOM 5041 C CB . ALA B 1 265 ? -12.458 13.754 -24.008 1.00 62.05 ? 261 ALA B CB 1 ATOM 5042 N N . VAL B 1 266 ? -10.869 11.893 -22.243 1.00 58.44 ? 262 VAL B N 1 ATOM 5043 C CA . VAL B 1 266 ? -10.187 11.416 -21.045 1.00 68.67 ? 262 VAL B CA 1 ATOM 5044 C C . VAL B 1 266 ? -9.017 12.257 -20.546 1.00 83.36 ? 262 VAL B C 1 ATOM 5045 O O . VAL B 1 266 ? -7.931 12.240 -21.126 1.00 85.10 ? 262 VAL B O 1 ATOM 5046 C CB . VAL B 1 266 ? -9.645 9.984 -21.292 1.00 63.61 ? 262 VAL B CB 1 ATOM 5047 C CG1 . VAL B 1 266 ? -9.002 9.411 -20.030 1.00 66.43 ? 262 VAL B CG1 1 ATOM 5048 C CG2 . VAL B 1 266 ? -10.759 9.069 -21.800 1.00 75.86 ? 262 VAL B CG2 1 ATOM 5049 N N . VAL B 1 267 ? -9.274 13.022 -19.488 1.00 81.55 ? 263 VAL B N 1 ATOM 5050 C CA . VAL B 1 267 ? -8.458 13.048 -18.277 1.00 73.86 ? 263 VAL B CA 1 ATOM 5051 C C . VAL B 1 267 ? -6.966 12.771 -18.485 1.00 84.70 ? 263 VAL B C 1 ATOM 5052 O O . VAL B 1 267 ? -6.476 11.718 -18.072 1.00 90.58 ? 263 VAL B O 1 ATOM 5053 C CB . VAL B 1 267 ? -9.016 12.043 -17.240 1.00 73.23 ? 263 VAL B CB 1 ATOM 5054 C CG1 . VAL B 1 267 ? -8.454 12.339 -15.854 1.00 80.22 ? 263 VAL B CG1 1 ATOM 5055 C CG2 . VAL B 1 267 ? -10.541 12.108 -17.207 1.00 79.23 ? 263 VAL B CG2 1 ATOM 5056 N N . LEU B 1 268 ? -6.240 13.679 -19.129 1.00 93.93 ? 264 LEU B N 1 ATOM 5057 C CA . LEU B 1 268 ? -4.793 13.513 -19.229 1.00 91.86 ? 264 LEU B CA 1 ATOM 5058 C C . LEU B 1 268 ? -4.126 14.020 -17.954 1.00 94.22 ? 264 LEU B C 1 ATOM 5059 O O . LEU B 1 268 ? -4.263 15.187 -17.586 1.00 98.50 ? 264 LEU B O 1 ATOM 5060 C CB . LEU B 1 268 ? -4.235 14.235 -20.456 1.00 89.48 ? 264 LEU B CB 1 ATOM 5061 C CG . LEU B 1 268 ? -4.672 13.690 -21.821 1.00 88.54 ? 264 LEU B CG 1 ATOM 5062 C CD1 . LEU B 1 268 ? -3.724 14.192 -22.896 1.00 75.28 ? 264 LEU B CD1 1 ATOM 5063 C CD2 . LEU B 1 268 ? -4.754 12.159 -21.847 1.00 79.61 ? 264 LEU B CD2 1 ATOM 5064 N N . ASN B 1 269 ? -3.408 13.122 -17.286 1.00 95.30 ? 265 ASN B N 1 ATOM 5065 C CA . ASN B 1 269 ? -2.774 13.426 -16.009 1.00 96.87 ? 265 ASN B CA 1 ATOM 5066 C C . ASN B 1 269 ? -1.564 12.522 -15.777 1.00 96.09 ? 265 ASN B C 1 ATOM 5067 O O . ASN B 1 269 ? -1.100 11.853 -16.701 1.00 91.33 ? 265 ASN B O 1 ATOM 5068 C CB . ASN B 1 269 ? -3.783 13.289 -14.866 1.00 101.74 ? 265 ASN B CB 1 ATOM 5069 C CG . ASN B 1 269 ? -4.292 11.871 -14.698 1.00 99.33 ? 265 ASN B CG 1 ATOM 5070 O OD1 . ASN B 1 269 ? -5.073 11.379 -15.511 1.00 97.62 ? 265 ASN B OD1 1 ATOM 5071 N ND2 . ASN B 1 269 ? -3.866 11.212 -13.626 1.00 98.39 ? 265 ASN B ND2 1 ATOM 5072 N N . ASP B 1 270 ? -1.044 12.524 -14.553 1.00 100.83 ? 266 ASP B N 1 ATOM 5073 C CA . ASP B 1 270 ? 0.176 11.786 -14.229 1.00 103.10 ? 266 ASP B CA 1 ATOM 5074 C C . ASP B 1 270 ? 0.095 10.305 -14.603 1.00 98.71 ? 266 ASP B C 1 ATOM 5075 O O . ASP B 1 270 ? 1.002 9.776 -15.248 1.00 96.30 ? 266 ASP B O 1 ATOM 5076 C CB . ASP B 1 270 ? 0.495 11.926 -12.738 1.00 110.32 ? 266 ASP B CB 1 ATOM 5077 C CG . ASP B 1 270 ? -0.625 11.426 -11.849 1.00 112.48 ? 266 ASP B CG 1 ATOM 5078 O OD1 . ASP B 1 270 ? -1.790 11.434 -12.297 1.00 113.60 ? 266 ASP B OD1 1 ATOM 5079 O OD2 . ASP B 1 270 ? -0.340 11.025 -10.701 1.00 112.62 ? 266 ASP B OD2 1 ATOM 5080 N N . ARG B 1 271 ? -0.984 9.640 -14.202 1.00 95.14 ? 267 ARG B N 1 ATOM 5081 C CA . ARG B 1 271 ? -1.137 8.213 -14.473 1.00 87.78 ? 267 ARG B CA 1 ATOM 5082 C C . ARG B 1 271 ? -1.499 7.952 -15.931 1.00 81.19 ? 267 ARG B C 1 ATOM 5083 O O . ARG B 1 271 ? -0.867 7.128 -16.593 1.00 78.86 ? 267 ARG B O 1 ATOM 5084 C CB . ARG B 1 271 ? -2.199 7.599 -13.560 1.00 88.46 ? 267 ARG B CB 1 ATOM 5085 C CG . ARG B 1 271 ? -2.429 6.116 -13.812 1.00 82.08 ? 267 ARG B CG 1 ATOM 5086 C CD . ARG B 1 271 ? -3.185 5.460 -12.673 1.00 71.91 ? 267 ARG B CD 1 ATOM 5087 N NE . ARG B 1 271 ? -4.509 6.047 -12.486 1.00 96.87 ? 267 ARG B NE 1 ATOM 5088 C CZ . ARG B 1 271 ? -5.568 5.768 -13.239 1.00 98.07 ? 267 ARG B CZ 1 ATOM 5089 N NH1 . ARG B 1 271 ? -5.471 4.909 -14.244 1.00 85.92 ? 267 ARG B NH1 1 ATOM 5090 N NH2 . ARG B 1 271 ? -6.730 6.354 -12.991 1.00 103.00 ? 267 ARG B NH2 1 ATOM 5091 N N . VAL B 1 272 ? -2.513 8.655 -16.430 1.00 83.31 ? 268 VAL B N 1 ATOM 5092 C CA . VAL B 1 272 ? -2.938 8.491 -17.816 1.00 87.62 ? 268 VAL B CA 1 ATOM 5093 C C . VAL B 1 272 ? -2.270 9.550 -18.685 1.00 88.50 ? 268 VAL B C 1 ATOM 5094 O O . VAL B 1 272 ? -2.645 10.722 -18.651 1.00 98.68 ? 268 VAL B O 1 ATOM 5095 C CB . VAL B 1 272 ? -4.473 8.597 -17.950 1.00 86.60 ? 268 VAL B CB 1 ATOM 5096 C CG1 . VAL B 1 272 ? -4.910 8.377 -19.398 1.00 85.44 ? 268 VAL B CG1 1 ATOM 5097 C CG2 . VAL B 1 272 ? -5.152 7.595 -17.025 1.00 83.22 ? 268 VAL B CG2 1 ATOM 5098 N N . LYS B 1 273 ? -1.303 9.114 -19.486 1.00 77.78 ? 269 LYS B N 1 ATOM 5099 C CA . LYS B 1 273 ? -0.528 10.014 -20.333 1.00 86.99 ? 269 LYS B CA 1 ATOM 5100 C C . LYS B 1 273 ? -0.904 9.853 -21.793 1.00 85.79 ? 269 LYS B C 1 ATOM 5101 O O . LYS B 1 273 ? -1.733 9.016 -22.136 1.00 85.59 ? 269 LYS B O 1 ATOM 5102 C CB . LYS B 1 273 ? 0.968 9.753 -20.152 1.00 82.16 ? 269 LYS B CB 1 ATOM 5103 C CG . LYS B 1 273 ? 1.522 10.284 -18.849 1.00 92.16 ? 269 LYS B CG 1 ATOM 5104 C CD . LYS B 1 273 ? 1.664 11.797 -18.890 1.00 95.42 ? 269 LYS B CD 1 ATOM 5105 C CE . LYS B 1 273 ? 2.141 12.342 -17.557 1.00 101.75 ? 269 LYS B CE 1 ATOM 5106 N NZ . LYS B 1 273 ? 3.403 11.692 -17.112 1.00 99.77 ? 269 LYS B NZ 1 ATOM 5107 N N . GLN B 1 274 ? -0.284 10.654 -22.652 1.00 79.33 ? 270 GLN B N 1 ATOM 5108 C CA . GLN B 1 274 ? -0.424 10.470 -24.087 1.00 73.40 ? 270 GLN B CA 1 ATOM 5109 C C . GLN B 1 274 ? 0.820 10.943 -24.827 1.00 82.74 ? 270 GLN B C 1 ATOM 5110 O O . GLN B 1 274 ? 1.441 11.940 -24.457 1.00 95.00 ? 270 GLN B O 1 ATOM 5111 C CB . GLN B 1 274 ? -1.656 11.206 -24.611 1.00 68.62 ? 270 GLN B CB 1 ATOM 5112 C CG . GLN B 1 274 ? -1.801 11.126 -26.124 1.00 68.71 ? 270 GLN B CG 1 ATOM 5113 C CD . GLN B 1 274 ? -3.199 11.466 -26.612 1.00 79.42 ? 270 GLN B CD 1 ATOM 5114 O OE1 . GLN B 1 274 ? -4.143 11.560 -25.827 1.00 96.65 ? 270 GLN B OE1 1 ATOM 5115 N NE2 . GLN B 1 274 ? -3.337 11.646 -27.921 1.00 76.86 ? 270 GLN B NE2 1 ATOM 5116 N N . VAL B 1 275 ? 1.174 10.206 -25.874 1.00 76.91 ? 271 VAL B N 1 ATOM 5117 C CA . VAL B 1 275 ? 2.269 10.576 -26.760 1.00 76.85 ? 271 VAL B CA 1 ATOM 5118 C C . VAL B 1 275 ? 1.823 10.351 -28.198 1.00 70.01 ? 271 VAL B C 1 ATOM 5119 O O . VAL B 1 275 ? 1.489 9.228 -28.577 1.00 80.72 ? 271 VAL B O 1 ATOM 5120 C CB . VAL B 1 275 ? 3.544 9.760 -26.461 1.00 89.16 ? 271 VAL B CB 1 ATOM 5121 C CG1 . VAL B 1 275 ? 4.585 9.952 -27.559 1.00 82.25 ? 271 VAL B CG1 1 ATOM 5122 C CG2 . VAL B 1 275 ? 4.111 10.150 -25.104 1.00 108.60 ? 271 VAL B CG2 1 ATOM 5123 N N . SER B 1 276 ? 1.818 11.419 -28.991 1.00 71.19 ? 272 SER B N 1 ATOM 5124 C CA . SER B 1 276 ? 1.352 11.347 -30.371 1.00 69.70 ? 272 SER B CA 1 ATOM 5125 C C . SER B 1 276 ? -0.070 10.778 -30.394 1.00 77.46 ? 272 SER B C 1 ATOM 5126 O O . SER B 1 276 ? -0.977 11.361 -29.798 1.00 84.64 ? 272 SER B O 1 ATOM 5127 C CB . SER B 1 276 ? 2.309 10.501 -31.216 1.00 70.68 ? 272 SER B CB 1 ATOM 5128 O OG . SER B 1 276 ? 3.634 10.998 -31.134 1.00 84.77 ? 272 SER B OG 1 ATOM 5129 N N . GLY B 1 277 ? -0.262 9.644 -31.064 1.00 77.25 ? 273 GLY B N 1 ATOM 5130 C CA . GLY B 1 277 ? -1.556 8.986 -31.099 1.00 69.41 ? 273 GLY B CA 1 ATOM 5131 C C . GLY B 1 277 ? -1.672 7.904 -30.043 1.00 66.81 ? 273 GLY B C 1 ATOM 5132 O O . GLY B 1 277 ? -2.722 7.280 -29.896 1.00 76.66 ? 273 GLY B O 1 ATOM 5133 N N . THR B 1 278 ? -0.592 7.696 -29.297 1.00 62.43 ? 274 THR B N 1 ATOM 5134 C CA . THR B 1 278 ? -0.516 6.597 -28.341 1.00 61.86 ? 274 THR B CA 1 ATOM 5135 C C . THR B 1 278 ? -1.031 6.999 -26.964 1.00 60.10 ? 274 THR B C 1 ATOM 5136 O O . THR B 1 278 ? -0.504 7.915 -26.334 1.00 75.82 ? 274 THR B O 1 ATOM 5137 C CB . THR B 1 278 ? 0.934 6.084 -28.201 1.00 70.61 ? 274 THR B CB 1 ATOM 5138 O OG1 . THR B 1 278 ? 1.439 5.720 -29.492 1.00 60.63 ? 274 THR B OG1 1 ATOM 5139 C CG2 . THR B 1 278 ? 1.000 4.875 -27.264 1.00 65.33 ? 274 THR B CG2 1 ATOM 5140 N N . LEU B 1 279 ? -2.064 6.298 -26.505 1.00 60.11 ? 275 LEU B N 1 ATOM 5141 C CA . LEU B 1 279 ? -2.589 6.480 -25.157 1.00 70.68 ? 275 LEU B CA 1 ATOM 5142 C C . LEU B 1 279 ? -1.934 5.476 -24.217 1.00 63.43 ? 275 LEU B C 1 ATOM 5143 O O . LEU B 1 279 ? -2.066 4.266 -24.405 1.00 70.45 ? 275 LEU B O 1 ATOM 5144 C CB . LEU B 1 279 ? -4.110 6.311 -25.138 1.00 63.25 ? 275 LEU B CB 1 ATOM 5145 C CG . LEU B 1 279 ? -4.786 6.435 -23.769 1.00 51.28 ? 275 LEU B CG 1 ATOM 5146 C CD1 . LEU B 1 279 ? -4.580 7.826 -23.188 1.00 59.71 ? 275 LEU B CD1 1 ATOM 5147 C CD2 . LEU B 1 279 ? -6.267 6.115 -23.873 1.00 70.10 ? 275 LEU B CD2 1 ATOM 5148 N N . ILE B 1 280 ? -1.228 5.982 -23.209 1.00 63.54 ? 276 ILE B N 1 ATOM 5149 C CA . ILE B 1 280 ? -0.533 5.124 -22.256 1.00 67.67 ? 276 ILE B CA 1 ATOM 5150 C C . ILE B 1 280 ? -1.168 5.224 -20.878 1.00 64.37 ? 276 ILE B C 1 ATOM 5151 O O . ILE B 1 280 ? -1.474 6.315 -20.395 1.00 68.54 ? 276 ILE B O 1 ATOM 5152 C CB . ILE B 1 280 ? 0.963 5.480 -22.140 1.00 75.55 ? 276 ILE B CB 1 ATOM 5153 C CG1 . ILE B 1 280 ? 1.605 5.540 -23.529 1.00 78.53 ? 276 ILE B CG1 1 ATOM 5154 C CG2 . ILE B 1 280 ? 1.683 4.457 -21.254 1.00 68.02 ? 276 ILE B CG2 1 ATOM 5155 C CD1 . ILE B 1 280 ? 3.029 6.048 -23.526 1.00 70.47 ? 276 ILE B CD1 1 ATOM 5156 N N . ILE B 1 281 ? -1.362 4.067 -20.259 1.00 63.52 ? 277 ILE B N 1 ATOM 5157 C CA . ILE B 1 281 ? -1.847 3.984 -18.892 1.00 73.86 ? 277 ILE B CA 1 ATOM 5158 C C . ILE B 1 281 ? -0.738 3.403 -18.020 1.00 83.90 ? 277 ILE B C 1 ATOM 5159 O O . ILE B 1 281 ? -0.189 2.343 -18.321 1.00 91.10 ? 277 ILE B O 1 ATOM 5160 C CB . ILE B 1 281 ? -3.131 3.124 -18.799 1.00 81.34 ? 277 ILE B CB 1 ATOM 5161 C CG1 . ILE B 1 281 ? -4.291 3.844 -19.490 1.00 80.06 ? 277 ILE B CG1 1 ATOM 5162 C CG2 . ILE B 1 281 ? -3.497 2.834 -17.347 1.00 81.91 ? 277 ILE B CG2 1 ATOM 5163 C CD1 . ILE B 1 281 ? -5.516 2.979 -19.709 1.00 71.88 ? 277 ILE B CD1 1 ATOM 5164 N N . LYS B 1 282 ? -0.415 4.109 -16.942 1.00 78.79 ? 278 LYS B N 1 ATOM 5165 C CA . LYS B 1 282 ? 0.609 3.676 -15.996 1.00 90.93 ? 278 LYS B CA 1 ATOM 5166 C C . LYS B 1 282 ? -0.003 2.626 -15.081 1.00 98.48 ? 278 LYS B C 1 ATOM 5167 O O . LYS B 1 282 ? -1.043 2.065 -15.420 1.00 90.94 ? 278 LYS B O 1 ATOM 5168 C CB . LYS B 1 282 ? 1.157 4.862 -15.202 1.00 88.67 ? 278 LYS B CB 1 ATOM 5169 C CG . LYS B 1 282 ? 2.027 5.792 -16.025 1.00 92.47 ? 278 LYS B CG 1 ATOM 5170 C CD . LYS B 1 282 ? 2.631 6.886 -15.167 1.00 97.93 ? 278 LYS B CD 1 ATOM 5171 C CE . LYS B 1 282 ? 3.412 7.881 -16.006 1.00 102.69 ? 278 LYS B CE 1 ATOM 5172 N NZ . LYS B 1 282 ? 4.569 7.251 -16.701 1.00 105.12 ? 278 LYS B NZ 1 ATOM 5173 N N . ASP B 1 283 ? 0.647 2.322 -13.957 1.00 112.49 ? 279 ASP B N 1 ATOM 5174 C CA . ASP B 1 283 ? 0.169 1.252 -13.088 1.00 106.85 ? 279 ASP B CA 1 ATOM 5175 C C . ASP B 1 283 ? -1.312 1.494 -12.820 1.00 97.78 ? 279 ASP B C 1 ATOM 5176 O O . ASP B 1 283 ? -1.710 2.541 -12.308 1.00 100.61 ? 279 ASP B O 1 ATOM 5177 C CB . ASP B 1 283 ? 0.976 1.212 -11.784 1.00 103.55 ? 279 ASP B CB 1 ATOM 5178 C CG . ASP B 1 283 ? 0.566 0.071 -10.867 1.00 105.25 ? 279 ASP B CG 1 ATOM 5179 O OD1 . ASP B 1 283 ? -0.637 -0.057 -10.556 1.00 110.59 ? 279 ASP B OD1 1 ATOM 5180 O OD2 . ASP B 1 283 ? 1.457 -0.697 -10.446 1.00 106.15 ? 279 ASP B OD2 1 ATOM 5181 N N . ALA B 1 284 ? -2.113 0.496 -13.179 1.00 91.72 ? 280 ALA B N 1 ATOM 5182 C CA . ALA B 1 284 ? -3.535 0.691 -13.423 1.00 85.83 ? 280 ALA B CA 1 ATOM 5183 C C . ALA B 1 284 ? -4.419 0.097 -12.339 1.00 92.51 ? 280 ALA B C 1 ATOM 5184 O O . ALA B 1 284 ? -3.939 -0.409 -11.323 1.00 98.59 ? 280 ALA B O 1 ATOM 5185 C CB . ALA B 1 284 ? -3.910 0.099 -14.787 1.00 80.10 ? 280 ALA B CB 1 ATOM 5186 N N . VAL B 1 285 ? -5.722 0.189 -12.575 1.00 94.91 ? 281 VAL B N 1 ATOM 5187 C CA . VAL B 1 285 ? -6.727 -0.417 -11.719 1.00 101.28 ? 281 VAL B CA 1 ATOM 5188 C C . VAL B 1 285 ? -7.767 -1.104 -12.594 1.00 97.58 ? 281 VAL B C 1 ATOM 5189 O O . VAL B 1 285 ? -7.844 -0.848 -13.796 1.00 90.05 ? 281 VAL B O 1 ATOM 5190 C CB . VAL B 1 285 ? -7.405 0.630 -10.818 1.00 98.58 ? 281 VAL B CB 1 ATOM 5191 C CG1 . VAL B 1 285 ? -6.407 1.180 -9.812 1.00 101.20 ? 281 VAL B CG1 1 ATOM 5192 C CG2 . VAL B 1 285 ? -8.000 1.756 -11.660 1.00 90.36 ? 281 VAL B CG2 1 ATOM 5193 N N . VAL B 1 286 ? -8.562 -1.979 -11.990 1.00 94.39 ? 282 VAL B N 1 ATOM 5194 C CA . VAL B 1 286 ? -9.635 -2.656 -12.707 1.00 88.81 ? 282 VAL B CA 1 ATOM 5195 C C . VAL B 1 286 ? -10.686 -1.637 -13.147 1.00 95.54 ? 282 VAL B C 1 ATOM 5196 O O . VAL B 1 286 ? -11.457 -1.886 -14.074 1.00 90.15 ? 282 VAL B O 1 ATOM 5197 C CB . VAL B 1 286 ? -10.283 -3.754 -11.834 1.00 90.92 ? 282 VAL B CB 1 ATOM 5198 C CG1 . VAL B 1 286 ? -11.373 -4.499 -12.601 1.00 71.02 ? 282 VAL B CG1 1 ATOM 5199 C CG2 . VAL B 1 286 ? -9.219 -4.732 -11.341 1.00 92.51 ? 282 VAL B CG2 1 ATOM 5200 N N . GLU B 1 287 ? -10.694 -0.480 -12.490 1.00 99.91 ? 283 GLU B N 1 ATOM 5201 C CA . GLU B 1 287 ? -11.649 0.580 -12.800 1.00 92.77 ? 283 GLU B CA 1 ATOM 5202 C C . GLU B 1 287 ? -11.344 1.234 -14.150 1.00 89.31 ? 283 GLU B C 1 ATOM 5203 O O . GLU B 1 287 ? -12.181 1.952 -14.701 1.00 78.48 ? 283 GLU B O 1 ATOM 5204 C CB . GLU B 1 287 ? -11.651 1.637 -11.690 1.00 86.31 ? 283 GLU B CB 1 ATOM 5205 C CG . GLU B 1 287 ? -12.096 1.113 -10.330 1.00 95.94 ? 283 GLU B CG 1 ATOM 5206 C CD . GLU B 1 287 ? -10.992 0.382 -9.590 1.00 106.01 ? 283 GLU B CD 1 ATOM 5207 O OE1 . GLU B 1 287 ? -10.209 1.048 -8.878 1.00 104.93 ? 283 GLU B OE1 1 ATOM 5208 O OE2 . GLU B 1 287 ? -10.906 -0.857 -9.720 1.00 103.91 ? 283 GLU B OE2 1 ATOM 5209 N N . ASP B 1 288 ? -10.147 0.985 -14.675 1.00 88.28 ? 284 ASP B N 1 ATOM 5210 C CA . ASP B 1 288 ? -9.765 1.491 -15.991 1.00 83.84 ? 284 ASP B CA 1 ATOM 5211 C C . ASP B 1 288 ? -10.302 0.591 -17.100 1.00 77.69 ? 284 ASP B C 1 ATOM 5212 O O . ASP B 1 288 ? -10.340 0.988 -18.266 1.00 65.23 ? 284 ASP B O 1 ATOM 5213 C CB . ASP B 1 288 ? -8.241 1.605 -16.107 1.00 79.31 ? 284 ASP B CB 1 ATOM 5214 C CG . ASP B 1 288 ? -7.677 2.777 -15.325 1.00 86.97 ? 284 ASP B CG 1 ATOM 5215 O OD1 . ASP B 1 288 ? -8.390 3.788 -15.153 1.00 87.82 ? 284 ASP B OD1 1 ATOM 5216 O OD2 . ASP B 1 288 ? -6.509 2.689 -14.889 1.00 91.31 ? 284 ASP B OD2 1 ATOM 5217 N N . SER B 1 289 ? -10.712 -0.621 -16.733 1.00 79.28 ? 285 SER B N 1 ATOM 5218 C CA . SER B 1 289 ? -11.265 -1.570 -17.695 1.00 68.94 ? 285 SER B CA 1 ATOM 5219 C C . SER B 1 289 ? -12.456 -0.965 -18.419 1.00 78.03 ? 285 SER B C 1 ATOM 5220 O O . SER B 1 289 ? -13.330 -0.362 -17.796 1.00 82.59 ? 285 SER B O 1 ATOM 5221 C CB . SER B 1 289 ? -11.689 -2.863 -16.998 1.00 74.81 ? 285 SER B CB 1 ATOM 5222 O OG . SER B 1 289 ? -10.584 -3.506 -16.393 1.00 88.25 ? 285 SER B OG 1 ATOM 5223 N N . GLY B 1 290 ? -12.489 -1.122 -19.738 1.00 68.26 ? 286 GLY B N 1 ATOM 5224 C CA . GLY B 1 290 ? -13.594 -0.602 -20.516 1.00 60.27 ? 286 GLY B CA 1 ATOM 5225 C C . GLY B 1 290 ? -13.355 -0.591 -22.010 1.00 56.23 ? 286 GLY B C 1 ATOM 5226 O O . GLY B 1 290 ? -12.488 -1.293 -22.531 1.00 57.13 ? 286 GLY B O 1 ATOM 5227 N N . LYS B 1 291 ? -14.146 0.231 -22.690 1.00 62.71 ? 287 LYS B N 1 ATOM 5228 C CA . LYS B 1 291 ? -14.160 0.308 -24.142 1.00 63.14 ? 287 LYS B CA 1 ATOM 5229 C C . LYS B 1 291 ? -13.815 1.729 -24.577 1.00 64.80 ? 287 LYS B C 1 ATOM 5230 O O . LYS B 1 291 ? -14.591 2.657 -24.351 1.00 69.80 ? 287 LYS B O 1 ATOM 5231 C CB . LYS B 1 291 ? -15.539 -0.124 -24.649 1.00 63.67 ? 287 LYS B CB 1 ATOM 5232 C CG . LYS B 1 291 ? -15.859 0.166 -26.099 1.00 64.06 ? 287 LYS B CG 1 ATOM 5233 C CD . LYS B 1 291 ? -17.312 -0.208 -26.353 1.00 94.87 ? 287 LYS B CD 1 ATOM 5234 C CE . LYS B 1 291 ? -17.730 -0.022 -27.796 1.00 96.35 ? 287 LYS B CE 1 ATOM 5235 N NZ . LYS B 1 291 ? -19.207 -0.126 -27.943 1.00 90.65 ? 287 LYS B NZ 1 ATOM 5236 N N . TYR B 1 292 ? -12.648 1.897 -25.195 1.00 55.84 ? 288 TYR B N 1 ATOM 5237 C CA . TYR B 1 292 ? -12.166 3.223 -25.575 1.00 54.06 ? 288 TYR B CA 1 ATOM 5238 C C . TYR B 1 292 ? -12.389 3.493 -27.056 1.00 56.29 ? 288 TYR B C 1 ATOM 5239 O O . TYR B 1 292 ? -12.860 2.627 -27.794 1.00 66.84 ? 288 TYR B O 1 ATOM 5240 C CB . TYR B 1 292 ? -10.678 3.373 -25.243 1.00 60.74 ? 288 TYR B CB 1 ATOM 5241 C CG . TYR B 1 292 ? -10.349 3.151 -23.781 1.00 64.42 ? 288 TYR B CG 1 ATOM 5242 C CD1 . TYR B 1 292 ? -10.219 1.870 -23.268 1.00 60.88 ? 288 TYR B CD1 1 ATOM 5243 C CD2 . TYR B 1 292 ? -10.165 4.221 -22.917 1.00 64.36 ? 288 TYR B CD2 1 ATOM 5244 C CE1 . TYR B 1 292 ? -9.919 1.660 -21.936 1.00 57.12 ? 288 TYR B CE1 1 ATOM 5245 C CE2 . TYR B 1 292 ? -9.863 4.018 -21.583 1.00 63.29 ? 288 TYR B CE2 1 ATOM 5246 C CZ . TYR B 1 292 ? -9.742 2.736 -21.099 1.00 62.17 ? 288 TYR B CZ 1 ATOM 5247 O OH . TYR B 1 292 ? -9.443 2.527 -19.771 1.00 81.05 ? 288 TYR B OH 1 ATOM 5248 N N . LEU B 1 293 ? -12.042 4.704 -27.479 1.00 59.48 ? 289 LEU B N 1 ATOM 5249 C CA . LEU B 1 293 ? -12.184 5.106 -28.872 1.00 61.98 ? 289 LEU B CA 1 ATOM 5250 C C . LEU B 1 293 ? -11.047 6.036 -29.280 1.00 58.83 ? 289 LEU B C 1 ATOM 5251 O O . LEU B 1 293 ? -10.682 6.946 -28.536 1.00 65.02 ? 289 LEU B O 1 ATOM 5252 C CB . LEU B 1 293 ? -13.538 5.783 -29.096 1.00 59.26 ? 289 LEU B CB 1 ATOM 5253 C CG . LEU B 1 293 ? -13.819 6.303 -30.507 1.00 60.71 ? 289 LEU B CG 1 ATOM 5254 C CD1 . LEU B 1 293 ? -13.842 5.160 -31.518 1.00 64.52 ? 289 LEU B CD1 1 ATOM 5255 C CD2 . LEU B 1 293 ? -15.128 7.079 -30.531 1.00 56.92 ? 289 LEU B CD2 1 ATOM 5256 N N . CYS B 1 294 ? -10.496 5.798 -30.465 1.00 50.71 ? 290 CYS B N 1 ATOM 5257 C CA . CYS B 1 294 ? -9.419 6.620 -31.001 1.00 51.53 ? 290 CYS B CA 1 ATOM 5258 C C . CYS B 1 294 ? -9.874 7.315 -32.276 1.00 51.30 ? 290 CYS B C 1 ATOM 5259 O O . CYS B 1 294 ? -10.091 6.669 -33.301 1.00 57.10 ? 290 CYS B O 1 ATOM 5260 C CB . CYS B 1 294 ? -8.176 5.768 -31.275 1.00 69.35 ? 290 CYS B CB 1 ATOM 5261 S SG . CYS B 1 294 ? -6.914 6.596 -32.266 1.00 70.55 ? 290 CYS B SG 1 ATOM 5262 N N . VAL B 1 295 ? -10.015 8.635 -32.203 1.00 59.73 ? 291 VAL B N 1 ATOM 5263 C CA . VAL B 1 295 ? -10.418 9.430 -33.357 1.00 50.13 ? 291 VAL B CA 1 ATOM 5264 C C . VAL B 1 295 ? -9.232 10.235 -33.861 1.00 55.53 ? 291 VAL B C 1 ATOM 5265 O O . VAL B 1 295 ? -8.584 10.955 -33.100 1.00 64.83 ? 291 VAL B O 1 ATOM 5266 C CB . VAL B 1 295 ? -11.582 10.383 -33.027 1.00 39.80 ? 291 VAL B CB 1 ATOM 5267 C CG1 . VAL B 1 295 ? -12.059 11.093 -34.294 1.00 42.18 ? 291 VAL B CG1 1 ATOM 5268 C CG2 . VAL B 1 295 ? -12.726 9.612 -32.377 1.00 52.20 ? 291 VAL B CG2 1 ATOM 5269 N N . VAL B 1 296 ? -8.953 10.096 -35.152 1.00 58.16 ? 292 VAL B N 1 ATOM 5270 C CA . VAL B 1 296 ? -7.883 10.836 -35.803 1.00 57.45 ? 292 VAL B CA 1 ATOM 5271 C C . VAL B 1 296 ? -8.508 11.811 -36.787 1.00 63.60 ? 292 VAL B C 1 ATOM 5272 O O . VAL B 1 296 ? -9.485 11.482 -37.462 1.00 68.94 ? 292 VAL B O 1 ATOM 5273 C CB . VAL B 1 296 ? -6.897 9.894 -36.518 1.00 55.92 ? 292 VAL B CB 1 ATOM 5274 C CG1 . VAL B 1 296 ? -5.830 10.689 -37.260 1.00 60.83 ? 292 VAL B CG1 1 ATOM 5275 C CG2 . VAL B 1 296 ? -6.258 8.950 -35.506 1.00 60.39 ? 292 VAL B CG2 1 ATOM 5276 N N . ASN B 1 297 ? -7.946 13.012 -36.859 1.00 68.87 ? 293 ASN B N 1 ATOM 5277 C CA . ASN B 1 297 ? -8.548 14.082 -37.640 1.00 69.17 ? 293 ASN B CA 1 ATOM 5278 C C . ASN B 1 297 ? -7.539 15.039 -38.258 1.00 57.52 ? 293 ASN B C 1 ATOM 5279 O O . ASN B 1 297 ? -6.518 15.367 -37.654 1.00 55.17 ? 293 ASN B O 1 ATOM 5280 C CB . ASN B 1 297 ? -9.521 14.872 -36.762 1.00 71.77 ? 293 ASN B CB 1 ATOM 5281 C CG . ASN B 1 297 ? -10.968 14.543 -37.058 1.00 73.31 ? 293 ASN B CG 1 ATOM 5282 O OD1 . ASN B 1 297 ? -11.387 14.536 -38.217 1.00 66.69 ? 293 ASN B OD1 1 ATOM 5283 N ND2 . ASN B 1 297 ? -11.741 14.265 -36.012 1.00 81.40 ? 293 ASN B ND2 1 ATOM 5284 N N . ASN B 1 298 ? -7.850 15.482 -39.470 1.00 58.08 ? 294 ASN B N 1 ATOM 5285 C CA . ASN B 1 298 ? -7.080 16.516 -40.142 1.00 53.57 ? 294 ASN B CA 1 ATOM 5286 C C . ASN B 1 298 ? -8.015 17.355 -41.010 1.00 52.38 ? 294 ASN B C 1 ATOM 5287 O O . ASN B 1 298 ? -9.238 17.241 -40.904 1.00 53.79 ? 294 ASN B O 1 ATOM 5288 C CB . ASN B 1 298 ? -5.944 15.903 -40.972 1.00 42.92 ? 294 ASN B CB 1 ATOM 5289 C CG . ASN B 1 298 ? -6.424 15.282 -42.271 1.00 51.85 ? 294 ASN B CG 1 ATOM 5290 O OD1 . ASN B 1 298 ? -7.584 14.889 -42.396 1.00 69.00 ? 294 ASN B OD1 1 ATOM 5291 N ND2 . ASN B 1 298 ? -5.525 15.182 -43.246 1.00 43.18 ? 294 ASN B ND2 1 ATOM 5292 N N . SER B 1 299 ? -7.442 18.202 -41.858 1.00 53.67 ? 295 SER B N 1 ATOM 5293 C CA . SER B 1 299 ? -8.235 19.114 -42.675 1.00 55.86 ? 295 SER B CA 1 ATOM 5294 C C . SER B 1 299 ? -9.040 18.368 -43.736 1.00 57.27 ? 295 SER B C 1 ATOM 5295 O O . SER B 1 299 ? -10.229 18.629 -43.927 1.00 72.04 ? 295 SER B O 1 ATOM 5296 C CB . SER B 1 299 ? -7.327 20.147 -43.345 1.00 56.41 ? 295 SER B CB 1 ATOM 5297 O OG . SER B 1 299 ? -6.665 19.596 -44.469 1.00 54.13 ? 295 SER B OG 1 ATOM 5298 N N . VAL B 1 300 ? -8.383 17.434 -44.415 1.00 48.45 ? 296 VAL B N 1 ATOM 5299 C CA . VAL B 1 300 ? -8.973 16.736 -45.554 1.00 52.23 ? 296 VAL B CA 1 ATOM 5300 C C . VAL B 1 300 ? -10.086 15.772 -45.146 1.00 60.36 ? 296 VAL B C 1 ATOM 5301 O O . VAL B 1 300 ? -10.977 15.475 -45.942 1.00 63.20 ? 296 VAL B O 1 ATOM 5302 C CB . VAL B 1 300 ? -7.892 15.935 -46.331 1.00 47.11 ? 296 VAL B CB 1 ATOM 5303 C CG1 . VAL B 1 300 ? -8.494 15.199 -47.534 1.00 63.36 ? 296 VAL B CG1 1 ATOM 5304 C CG2 . VAL B 1 300 ? -6.768 16.855 -46.782 1.00 62.28 ? 296 VAL B CG2 1 ATOM 5305 N N . GLY B 1 301 ? -10.055 15.307 -43.902 1.00 57.41 ? 297 GLY B N 1 ATOM 5306 C CA . GLY B 1 301 ? -10.759 14.088 -43.556 1.00 57.27 ? 297 GLY B CA 1 ATOM 5307 C C . GLY B 1 301 ? -10.423 13.578 -42.171 1.00 56.31 ? 297 GLY B C 1 ATOM 5308 O O . GLY B 1 301 ? -10.167 14.347 -41.243 1.00 56.17 ? 297 GLY B O 1 ATOM 5309 N N . GLY B 1 302 ? -10.448 12.256 -42.048 1.00 66.34 ? 298 GLY B N 1 ATOM 5310 C CA . GLY B 1 302 ? -10.157 11.563 -40.809 1.00 71.41 ? 298 GLY B CA 1 ATOM 5311 C C . GLY B 1 302 ? -11.332 10.807 -40.240 1.00 72.02 ? 298 GLY B C 1 ATOM 5312 O O . GLY B 1 302 ? -12.496 11.123 -40.486 1.00 80.41 ? 298 GLY B O 1 ATOM 5313 N N . GLU B 1 303 ? -10.988 9.778 -39.473 1.00 61.36 ? 299 GLU B N 1 ATOM 5314 C CA . GLU B 1 303 ? -11.909 8.717 -39.105 1.00 60.67 ? 299 GLU B CA 1 ATOM 5315 C C . GLU B 1 303 ? -11.557 8.214 -37.712 1.00 67.74 ? 299 GLU B C 1 ATOM 5316 O O . GLU B 1 303 ? -10.756 8.833 -37.009 1.00 67.71 ? 299 GLU B O 1 ATOM 5317 C CB . GLU B 1 303 ? -11.857 7.573 -40.127 1.00 73.83 ? 299 GLU B CB 1 ATOM 5318 C CG . GLU B 1 303 ? -12.323 7.953 -41.534 1.00 78.98 ? 299 GLU B CG 1 ATOM 5319 C CD . GLU B 1 303 ? -11.273 8.693 -42.343 1.00 79.36 ? 299 GLU B CD 1 ATOM 5320 O OE1 . GLU B 1 303 ? -10.071 8.579 -42.024 1.00 85.78 ? 299 GLU B OE1 1 ATOM 5321 O OE2 . GLU B 1 303 ? -11.654 9.401 -43.299 1.00 78.37 ? 299 GLU B OE2 1 ATOM 5322 N N . SER B 1 304 ? -12.153 7.092 -37.318 1.00 71.12 ? 300 SER B N 1 ATOM 5323 C CA . SER B 1 304 ? -12.023 6.601 -35.953 1.00 56.99 ? 300 SER B CA 1 ATOM 5324 C C . SER B 1 304 ? -11.805 5.095 -35.874 1.00 56.11 ? 300 SER B C 1 ATOM 5325 O O . SER B 1 304 ? -12.138 4.349 -36.796 1.00 64.32 ? 300 SER B O 1 ATOM 5326 C CB . SER B 1 304 ? -13.270 6.979 -35.155 1.00 57.75 ? 300 SER B CB 1 ATOM 5327 O OG . SER B 1 304 ? -14.444 6.548 -35.820 1.00 78.96 ? 300 SER B OG 1 ATOM 5328 N N . VAL B 1 305 ? -11.233 4.670 -34.752 1.00 47.42 ? 301 VAL B N 1 ATOM 5329 C CA . VAL B 1 305 ? -11.047 3.260 -34.433 1.00 49.38 ? 301 VAL B CA 1 ATOM 5330 C C . VAL B 1 305 ? -11.221 3.092 -32.930 1.00 58.56 ? 301 VAL B C 1 ATOM 5331 O O . VAL B 1 305 ? -10.739 3.919 -32.158 1.00 68.27 ? 301 VAL B O 1 ATOM 5332 C CB . VAL B 1 305 ? -9.655 2.747 -34.863 1.00 45.93 ? 301 VAL B CB 1 ATOM 5333 C CG1 . VAL B 1 305 ? -9.321 1.415 -34.181 1.00 53.25 ? 301 VAL B CG1 1 ATOM 5334 C CG2 . VAL B 1 305 ? -9.583 2.613 -36.379 1.00 53.31 ? 301 VAL B CG2 1 ATOM 5335 N N . GLU B 1 306 ? -11.895 2.023 -32.517 1.00 53.10 ? 302 GLU B N 1 ATOM 5336 C CA . GLU B 1 306 ? -12.138 1.776 -31.099 1.00 53.24 ? 302 GLU B CA 1 ATOM 5337 C C . GLU B 1 306 ? -11.333 0.579 -30.615 1.00 64.65 ? 302 GLU B C 1 ATOM 5338 O O . GLU B 1 306 ? -11.020 -0.323 -31.387 1.00 70.18 ? 302 GLU B O 1 ATOM 5339 C CB . GLU B 1 306 ? -13.627 1.554 -30.830 1.00 58.31 ? 302 GLU B CB 1 ATOM 5340 C CG . GLU B 1 306 ? -14.252 0.410 -31.601 1.00 81.03 ? 302 GLU B CG 1 ATOM 5341 C CD . GLU B 1 306 ? -15.537 -0.071 -30.961 1.00 74.81 ? 302 GLU B CD 1 ATOM 5342 O OE1 . GLU B 1 306 ? -15.480 -0.508 -29.793 1.00 82.16 ? 302 GLU B OE1 1 ATOM 5343 O OE2 . GLU B 1 306 ? -16.600 -0.009 -31.615 1.00 56.06 ? 302 GLU B OE2 1 ATOM 5344 N N . THR B 1 307 ? -10.993 0.590 -29.331 1.00 68.55 ? 303 THR B N 1 ATOM 5345 C CA . THR B 1 307 ? -10.135 -0.436 -28.751 1.00 61.77 ? 303 THR B CA 1 ATOM 5346 C C . THR B 1 307 ? -10.689 -0.912 -27.414 1.00 64.37 ? 303 THR B C 1 ATOM 5347 O O . THR B 1 307 ? -10.855 -0.125 -26.483 1.00 75.82 ? 303 THR B O 1 ATOM 5348 C CB . THR B 1 307 ? -8.698 0.088 -28.558 1.00 62.70 ? 303 THR B CB 1 ATOM 5349 O OG1 . THR B 1 307 ? -8.169 0.503 -29.824 1.00 68.40 ? 303 THR B OG1 1 ATOM 5350 C CG2 . THR B 1 307 ? -7.795 -0.987 -27.959 1.00 63.58 ? 303 THR B CG2 1 ATOM 5351 N N . VAL B 1 308 ? -10.974 -2.207 -27.329 1.00 64.32 ? 304 VAL B N 1 ATOM 5352 C CA . VAL B 1 308 ? -11.469 -2.801 -26.095 1.00 60.04 ? 304 VAL B CA 1 ATOM 5353 C C . VAL B 1 308 ? -10.297 -3.076 -25.166 1.00 58.65 ? 304 VAL B C 1 ATOM 5354 O O . VAL B 1 308 ? -9.212 -3.444 -25.618 1.00 77.01 ? 304 VAL B O 1 ATOM 5355 C CB . VAL B 1 308 ? -12.238 -4.112 -26.352 1.00 59.30 ? 304 VAL B CB 1 ATOM 5356 C CG1 . VAL B 1 308 ? -12.920 -4.587 -25.069 1.00 55.46 ? 304 VAL B CG1 1 ATOM 5357 C CG2 . VAL B 1 308 ? -13.257 -3.921 -27.472 1.00 61.28 ? 304 VAL B CG2 1 ATOM 5358 N N . LEU B 1 309 ? -10.518 -2.890 -23.869 1.00 54.86 ? 305 LEU B N 1 ATOM 5359 C CA . LEU B 1 309 ? -9.473 -3.117 -22.881 1.00 63.85 ? 305 LEU B CA 1 ATOM 5360 C C . LEU B 1 309 ? -10.020 -3.812 -21.643 1.00 65.39 ? 305 LEU B C 1 ATOM 5361 O O . LEU B 1 309 ? -11.171 -3.608 -21.255 1.00 64.36 ? 305 LEU B O 1 ATOM 5362 C CB . LEU B 1 309 ? -8.809 -1.798 -22.485 1.00 62.97 ? 305 LEU B CB 1 ATOM 5363 C CG . LEU B 1 309 ? -7.675 -1.920 -21.463 1.00 60.38 ? 305 LEU B CG 1 ATOM 5364 C CD1 . LEU B 1 309 ? -6.518 -2.749 -22.022 1.00 74.42 ? 305 LEU B CD1 1 ATOM 5365 C CD2 . LEU B 1 309 ? -7.205 -0.542 -21.033 1.00 67.57 ? 305 LEU B CD2 1 ATOM 5366 N N . THR B 1 310 ? -9.173 -4.634 -21.032 1.00 76.16 ? 306 THR B N 1 ATOM 5367 C CA . THR B 1 310 ? -9.513 -5.329 -19.801 1.00 73.06 ? 306 THR B CA 1 ATOM 5368 C C . THR B 1 310 ? -8.327 -5.289 -18.847 1.00 74.96 ? 306 THR B C 1 ATOM 5369 O O . THR B 1 310 ? -7.174 -5.262 -19.274 1.00 77.06 ? 306 THR B O 1 ATOM 5370 C CB . THR B 1 310 ? -9.912 -6.793 -20.064 1.00 58.15 ? 306 THR B CB 1 ATOM 5371 O OG1 . THR B 1 310 ? -10.778 -6.860 -21.203 1.00 54.96 ? 306 THR B OG1 1 ATOM 5372 C CG2 . THR B 1 310 ? -10.619 -7.384 -18.849 1.00 64.65 ? 306 THR B CG2 1 ATOM 5373 N N . VAL B 1 311 ? -8.620 -5.269 -17.553 1.00 78.92 ? 307 VAL B N 1 ATOM 5374 C CA . VAL B 1 311 ? -7.587 -5.319 -16.527 1.00 81.93 ? 307 VAL B CA 1 ATOM 5375 C C . VAL B 1 311 ? -7.832 -6.540 -15.654 1.00 87.55 ? 307 VAL B C 1 ATOM 5376 O O . VAL B 1 311 ? -8.978 -6.857 -15.330 1.00 89.93 ? 307 VAL B O 1 ATOM 5377 C CB . VAL B 1 311 ? -7.570 -4.039 -15.672 1.00 83.23 ? 307 VAL B CB 1 ATOM 5378 C CG1 . VAL B 1 311 ? -6.590 -4.176 -14.521 1.00 89.39 ? 307 VAL B CG1 1 ATOM 5379 C CG2 . VAL B 1 311 ? -7.218 -2.832 -16.539 1.00 69.28 ? 307 VAL B CG2 1 ATOM 5380 N N . THR B 1 312 ? -6.753 -7.220 -15.277 1.00 80.76 ? 308 THR B N 1 ATOM 5381 C CA . THR B 1 312 ? -6.868 -8.476 -14.549 1.00 82.53 ? 308 THR B CA 1 ATOM 5382 C C . THR B 1 312 ? -6.227 -8.404 -13.168 1.00 91.93 ? 308 THR B C 1 ATOM 5383 O O . THR B 1 312 ? -5.008 -8.290 -13.037 1.00 97.38 ? 308 THR B O 1 ATOM 5384 C CB . THR B 1 312 ? -6.228 -9.639 -15.338 1.00 84.44 ? 308 THR B CB 1 ATOM 5385 O OG1 . THR B 1 312 ? -4.815 -9.435 -15.448 1.00 105.73 ? 308 THR B OG1 1 ATOM 5386 C CG2 . THR B 1 312 ? -6.839 -9.741 -16.732 1.00 71.53 ? 308 THR B CG2 1 ATOM 5387 N N . ALA B 1 313 ? -7.072 -8.465 -12.144 1.00 91.63 ? 309 ALA B N 1 ATOM 5388 C CA . ALA B 1 313 ? -6.619 -8.587 -10.766 1.00 85.52 ? 309 ALA B CA 1 ATOM 5389 C C . ALA B 1 313 ? -6.513 -10.070 -10.406 1.00 87.86 ? 309 ALA B C 1 ATOM 5390 O O . ALA B 1 313 ? -7.199 -10.901 -11.002 1.00 77.82 ? 309 ALA B O 1 ATOM 5391 C CB . ALA B 1 313 ? -7.572 -7.856 -9.825 1.00 92.58 ? 309 ALA B CB 1 ATOM 5392 N N . PRO B 1 314 ? -5.650 -10.411 -9.436 1.00 99.93 ? 310 PRO B N 1 ATOM 5393 C CA . PRO B 1 314 ? -5.441 -11.821 -9.082 1.00 94.47 ? 310 PRO B CA 1 ATOM 5394 C C . PRO B 1 314 ? -6.676 -12.478 -8.472 1.00 86.31 ? 310 PRO B C 1 ATOM 5395 O O . PRO B 1 314 ? -7.365 -11.864 -7.657 1.00 93.50 ? 310 PRO B O 1 ATOM 5396 C CB . PRO B 1 314 ? -4.298 -11.760 -8.064 1.00 103.35 ? 310 PRO B CB 1 ATOM 5397 C CG . PRO B 1 314 ? -4.374 -10.389 -7.488 1.00 116.90 ? 310 PRO B CG 1 ATOM 5398 C CD . PRO B 1 314 ? -4.827 -9.509 -8.612 1.00 113.70 ? 310 PRO B CD 1 ATOM 5399 N N . LEU B 1 315 ? -6.944 -13.717 -8.872 1.00 86.23 ? 311 LEU B N 1 ATOM 5400 C CA . LEU B 1 315 ? -8.057 -14.480 -8.323 1.00 86.02 ? 311 LEU B CA 1 ATOM 5401 C C . LEU B 1 315 ? -7.722 -15.029 -6.943 1.00 92.22 ? 311 LEU B C 1 ATOM 5402 O O . LEU B 1 315 ? -6.715 -15.714 -6.763 1.00 100.09 ? 311 LEU B O 1 ATOM 5403 C CB . LEU B 1 315 ? -8.431 -15.635 -9.253 1.00 90.37 ? 311 LEU B CB 1 ATOM 5404 C CG . LEU B 1 315 ? -9.392 -15.322 -10.398 1.00 77.17 ? 311 LEU B CG 1 ATOM 5405 C CD1 . LEU B 1 315 ? -8.697 -14.532 -11.502 1.00 84.24 ? 311 LEU B CD1 1 ATOM 5406 C CD2 . LEU B 1 315 ? -9.988 -16.616 -10.930 1.00 73.57 ? 311 LEU B CD2 1 ATOM 5407 N N . SER B 1 316 ? -8.569 -14.717 -5.970 1.00 92.16 ? 312 SER B N 1 ATOM 5408 C CA . SER B 1 316 ? -8.451 -15.290 -4.636 1.00 100.73 ? 312 SER B CA 1 ATOM 5409 C C . SER B 1 316 ? -9.805 -15.214 -3.944 1.00 110.63 ? 312 SER B C 1 ATOM 5410 O O . SER B 1 316 ? -10.677 -14.453 -4.364 1.00 111.53 ? 312 SER B O 1 ATOM 5411 C CB . SER B 1 316 ? -7.383 -14.567 -3.816 1.00 96.36 ? 312 SER B CB 1 ATOM 5412 O OG . SER B 1 316 ? -7.160 -15.231 -2.584 1.00 98.51 ? 312 SER B OG 1 ATOM 5413 N N . ALA B 1 317 ? -9.972 -15.985 -2.875 1.00 110.77 ? 313 ALA B N 1 ATOM 5414 C CA . ALA B 1 317 ? -11.262 -16.076 -2.203 1.00 116.29 ? 313 ALA B CA 1 ATOM 5415 C C . ALA B 1 317 ? -11.182 -16.926 -0.943 1.00 119.69 ? 313 ALA B C 1 ATOM 5416 O O . ALA B 1 317 ? -10.200 -17.633 -0.714 1.00 121.56 ? 313 ALA B O 1 ATOM 5417 C CB . ALA B 1 317 ? -12.315 -16.656 -3.151 1.00 112.77 ? 313 ALA B CB 1 ATOM 5418 N N . LYS B 1 318 ? -12.227 -16.838 -0.126 1.00 124.70 ? 314 LYS B N 1 ATOM 5419 C CA . LYS B 1 318 ? -12.349 -17.653 1.075 1.00 123.24 ? 314 LYS B CA 1 ATOM 5420 C C . LYS B 1 318 ? -13.827 -17.857 1.397 1.00 120.04 ? 314 LYS B C 1 ATOM 5421 O O . LYS B 1 318 ? -14.684 -17.142 0.877 1.00 127.58 ? 314 LYS B O 1 ATOM 5422 C CB . LYS B 1 318 ? -11.625 -17.004 2.256 1.00 131.33 ? 314 LYS B CB 1 ATOM 5423 C CG . LYS B 1 318 ? -11.257 -17.983 3.363 1.00 135.86 ? 314 LYS B CG 1 ATOM 5424 C CD . LYS B 1 318 ? -10.808 -17.271 4.624 1.00 130.86 ? 314 LYS B CD 1 ATOM 5425 C CE . LYS B 1 318 ? -9.509 -16.516 4.415 1.00 141.56 ? 314 LYS B CE 1 ATOM 5426 N NZ . LYS B 1 318 ? -9.060 -15.859 5.671 1.00 139.41 ? 314 LYS B NZ 1 ATOM 5427 N N . ILE B 1 319 ? -14.119 -18.844 2.239 1.00 113.41 ? 315 ILE B N 1 ATOM 5428 C CA . ILE B 1 319 ? -15.492 -19.170 2.614 1.00 120.41 ? 315 ILE B CA 1 ATOM 5429 C C . ILE B 1 319 ? -15.781 -18.764 4.055 1.00 126.11 ? 315 ILE B C 1 ATOM 5430 O O . ILE B 1 319 ? -14.962 -18.980 4.949 1.00 121.01 ? 315 ILE B O 1 ATOM 5431 C CB . ILE B 1 319 ? -15.775 -20.677 2.443 1.00 118.62 ? 315 ILE B CB 1 ATOM 5432 C CG1 . ILE B 1 319 ? -15.630 -21.078 0.974 1.00 122.79 ? 315 ILE B CG1 1 ATOM 5433 C CG2 . ILE B 1 319 ? -17.171 -21.032 2.939 1.00 122.20 ? 315 ILE B CG2 1 ATOM 5434 C CD1 . ILE B 1 319 ? -14.221 -21.418 0.577 1.00 118.73 ? 315 ILE B CD1 1 ATOM 5435 N N . ASP B 1 320 ? -16.956 -18.174 4.262 1.00 125.91 ? 316 ASP B N 1 ATOM 5436 C CA . ASP B 1 320 ? -17.402 -17.744 5.583 1.00 122.98 ? 316 ASP B CA 1 ATOM 5437 C C . ASP B 1 320 ? -18.577 -18.596 6.077 1.00 120.13 ? 316 ASP B C 1 ATOM 5438 O O . ASP B 1 320 ? -19.611 -18.657 5.411 1.00 120.39 ? 316 ASP B O 1 ATOM 5439 C CB . ASP B 1 320 ? -17.810 -16.269 5.549 1.00 114.25 ? 316 ASP B CB 1 ATOM 5440 C CG . ASP B 1 320 ? -18.200 -15.740 6.915 1.00 120.24 ? 316 ASP B CG 1 ATOM 5441 O OD1 . ASP B 1 320 ? -17.493 -16.050 7.897 1.00 119.89 ? 316 ASP B OD1 1 ATOM 5442 O OD2 . ASP B 1 320 ? -19.215 -15.017 7.008 1.00 118.51 ? 316 ASP B OD2 1 ATOM 5443 N N . PRO B 1 321 ? -18.431 -19.264 7.237 1.00 117.88 ? 317 PRO B N 1 ATOM 5444 C CA . PRO B 1 321 ? -17.239 -19.379 8.087 1.00 126.34 ? 317 PRO B CA 1 ATOM 5445 C C . PRO B 1 321 ? -16.244 -20.406 7.546 1.00 122.09 ? 317 PRO B C 1 ATOM 5446 O O . PRO B 1 321 ? -16.648 -21.281 6.780 1.00 120.63 ? 317 PRO B O 1 ATOM 5447 C CB . PRO B 1 321 ? -17.814 -19.829 9.429 1.00 127.21 ? 317 PRO B CB 1 ATOM 5448 C CG . PRO B 1 321 ? -19.009 -20.633 9.059 1.00 122.20 ? 317 PRO B CG 1 ATOM 5449 C CD . PRO B 1 321 ? -19.581 -19.980 7.822 1.00 120.24 ? 317 PRO B CD 1 ATOM 5450 N N . PRO B 1 322 ? -14.960 -20.301 7.930 1.00 119.05 ? 318 PRO B N 1 ATOM 5451 C CA . PRO B 1 322 ? -13.989 -21.338 7.562 1.00 114.18 ? 318 PRO B CA 1 ATOM 5452 C C . PRO B 1 322 ? -14.409 -22.719 8.065 1.00 115.34 ? 318 PRO B C 1 ATOM 5453 O O . PRO B 1 322 ? -14.088 -23.723 7.433 1.00 120.85 ? 318 PRO B O 1 ATOM 5454 C CB . PRO B 1 322 ? -12.698 -20.868 8.239 1.00 109.82 ? 318 PRO B CB 1 ATOM 5455 C CG . PRO B 1 322 ? -12.859 -19.389 8.364 1.00 114.98 ? 318 PRO B CG 1 ATOM 5456 C CD . PRO B 1 322 ? -14.320 -19.176 8.632 1.00 115.70 ? 318 PRO B CD 1 ATOM 5457 N N . THR B 1 323 ? -15.106 -22.765 9.197 1.00 115.22 ? 319 THR B N 1 ATOM 5458 C CA . THR B 1 323 ? -15.659 -24.018 9.702 1.00 117.15 ? 319 THR B CA 1 ATOM 5459 C C . THR B 1 323 ? -16.841 -23.769 10.637 1.00 119.14 ? 319 THR B C 1 ATOM 5460 O O . THR B 1 323 ? -16.954 -22.699 11.234 1.00 122.88 ? 319 THR B O 1 ATOM 5461 C CB . THR B 1 323 ? -14.590 -24.842 10.445 1.00 115.67 ? 319 THR B CB 1 ATOM 5462 O OG1 . THR B 1 323 ? -15.171 -26.057 10.934 1.00 117.14 ? 319 THR B OG1 1 ATOM 5463 C CG2 . THR B 1 323 ? -14.001 -24.044 11.609 1.00 118.06 ? 319 THR B CG2 1 ATOM 5464 N N . GLN B 1 324 ? -17.718 -24.762 10.759 1.00 121.46 ? 320 GLN B N 1 ATOM 5465 C CA . GLN B 1 324 ? -18.858 -24.671 11.666 1.00 123.09 ? 320 GLN B CA 1 ATOM 5466 C C . GLN B 1 324 ? -19.413 -26.051 12.016 1.00 132.44 ? 320 GLN B C 1 ATOM 5467 O O . GLN B 1 324 ? -19.092 -27.042 11.361 1.00 131.84 ? 320 GLN B O 1 ATOM 5468 C CB . GLN B 1 324 ? -19.959 -23.803 11.056 1.00 120.60 ? 320 GLN B CB 1 ATOM 5469 C CG . GLN B 1 324 ? -20.449 -24.275 9.698 1.00 122.46 ? 320 GLN B CG 1 ATOM 5470 C CD . GLN B 1 324 ? -21.670 -23.509 9.223 1.00 126.68 ? 320 GLN B CD 1 ATOM 5471 O OE1 . GLN B 1 324 ? -22.196 -22.654 9.935 1.00 114.60 ? 320 GLN B OE1 1 ATOM 5472 N NE2 . GLN B 1 324 ? -22.128 -23.815 8.016 1.00 122.37 ? 320 GLN B NE2 1 ATOM 5473 N N . THR B 1 325 ? -20.232 -26.102 13.064 1.00 140.20 ? 321 THR B N 1 ATOM 5474 C CA . THR B 1 325 ? -20.910 -27.329 13.479 1.00 134.74 ? 321 THR B CA 1 ATOM 5475 C C . THR B 1 325 ? -22.412 -27.072 13.581 1.00 138.19 ? 321 THR B C 1 ATOM 5476 O O . THR B 1 325 ? -22.832 -25.970 13.938 1.00 140.82 ? 321 THR B O 1 ATOM 5477 C CB . THR B 1 325 ? -20.372 -27.842 14.830 1.00 134.93 ? 321 THR B CB 1 ATOM 5478 O OG1 . THR B 1 325 ? -18.956 -28.044 14.739 1.00 132.83 ? 321 THR B OG1 1 ATOM 5479 C CG2 . THR B 1 325 ? -21.047 -29.152 15.227 1.00 136.23 ? 321 THR B CG2 1 ATOM 5480 N N . VAL B 1 326 ? -23.220 -28.085 13.268 1.00 136.96 ? 322 VAL B N 1 ATOM 5481 C CA . VAL B 1 326 ? -24.670 -27.905 13.173 1.00 140.06 ? 322 VAL B CA 1 ATOM 5482 C C . VAL B 1 326 ? -25.440 -29.131 13.704 1.00 137.48 ? 322 VAL B C 1 ATOM 5483 O O . VAL B 1 326 ? -24.889 -30.224 13.845 1.00 135.30 ? 322 VAL B O 1 ATOM 5484 C CB . VAL B 1 326 ? -25.062 -27.569 11.701 1.00 138.61 ? 322 VAL B CB 1 ATOM 5485 C CG1 . VAL B 1 326 ? -26.559 -27.518 11.495 1.00 143.15 ? 322 VAL B CG1 1 ATOM 5486 C CG2 . VAL B 1 326 ? -24.462 -26.219 11.302 1.00 123.20 ? 322 VAL B CG2 1 ATOM 5487 N N . ASP B 1 327 ? -26.721 -28.909 13.988 1.00 137.22 ? 323 ASP B N 1 ATOM 5488 C CA . ASP B 1 327 ? -27.559 -29.749 14.849 1.00 136.09 ? 323 ASP B CA 1 ATOM 5489 C C . ASP B 1 327 ? -28.341 -30.899 14.187 1.00 143.36 ? 323 ASP B C 1 ATOM 5490 O O . ASP B 1 327 ? -29.303 -31.384 14.783 1.00 146.65 ? 323 ASP B O 1 ATOM 5491 C CB . ASP B 1 327 ? -28.545 -28.851 15.607 1.00 136.75 ? 323 ASP B CB 1 ATOM 5492 C CG . ASP B 1 327 ? -27.852 -27.928 16.596 1.00 142.13 ? 323 ASP B CG 1 ATOM 5493 O OD1 . ASP B 1 327 ? -26.746 -28.270 17.065 1.00 134.74 ? 323 ASP B OD1 1 ATOM 5494 O OD2 . ASP B 1 327 ? -28.421 -26.863 16.911 1.00 144.94 ? 323 ASP B OD2 1 ATOM 5495 N N . PHE B 1 328 ? -27.984 -31.299 12.965 1.00 144.47 ? 324 PHE B N 1 ATOM 5496 C CA . PHE B 1 328 ? -28.738 -32.333 12.230 1.00 145.38 ? 324 PHE B CA 1 ATOM 5497 C C . PHE B 1 328 ? -30.142 -31.885 11.812 1.00 148.44 ? 324 PHE B C 1 ATOM 5498 O O . PHE B 1 328 ? -31.139 -32.215 12.456 1.00 146.89 ? 324 PHE B O 1 ATOM 5499 C CB . PHE B 1 328 ? -28.859 -33.635 13.050 1.00 128.83 ? 324 PHE B CB 1 ATOM 5500 C CG . PHE B 1 328 ? -27.789 -34.642 12.765 1.00 134.12 ? 324 PHE B CG 1 ATOM 5501 C CD1 . PHE B 1 328 ? -27.738 -35.290 11.546 1.00 136.21 ? 324 PHE B CD1 1 ATOM 5502 C CD2 . PHE B 1 328 ? -26.854 -34.966 13.732 1.00 134.51 ? 324 PHE B CD2 1 ATOM 5503 C CE1 . PHE B 1 328 ? -26.760 -36.227 11.286 1.00 135.14 ? 324 PHE B CE1 1 ATOM 5504 C CE2 . PHE B 1 328 ? -25.874 -35.903 13.479 1.00 137.27 ? 324 PHE B CE2 1 ATOM 5505 C CZ . PHE B 1 328 ? -25.828 -36.537 12.256 1.00 138.24 ? 324 PHE B CZ 1 ATOM 5506 N N . GLY B 1 329 ? -30.191 -31.103 10.735 1.00 149.52 ? 325 GLY B N 1 ATOM 5507 C CA . GLY B 1 329 ? -31.433 -30.580 10.191 1.00 146.28 ? 325 GLY B CA 1 ATOM 5508 C C . GLY B 1 329 ? -31.534 -29.076 10.345 1.00 149.93 ? 325 GLY B C 1 ATOM 5509 O O . GLY B 1 329 ? -32.460 -28.444 9.836 1.00 151.25 ? 325 GLY B O 1 ATOM 5510 N N . ARG B 1 330 ? -30.567 -28.506 11.053 1.00 147.45 ? 326 ARG B N 1 ATOM 5511 C CA . ARG B 1 330 ? -30.474 -27.065 11.233 1.00 143.36 ? 326 ARG B CA 1 ATOM 5512 C C . ARG B 1 330 ? -29.719 -26.437 10.053 1.00 145.77 ? 326 ARG B C 1 ATOM 5513 O O . ARG B 1 330 ? -28.876 -27.095 9.442 1.00 145.91 ? 326 ARG B O 1 ATOM 5514 C CB . ARG B 1 330 ? -29.782 -26.769 12.565 1.00 139.07 ? 326 ARG B CB 1 ATOM 5515 C CG . ARG B 1 330 ? -29.439 -25.317 12.827 1.00 141.34 ? 326 ARG B CG 1 ATOM 5516 C CD . ARG B 1 330 ? -28.730 -25.175 14.154 1.00 141.49 ? 326 ARG B CD 1 ATOM 5517 N NE . ARG B 1 330 ? -28.571 -23.779 14.544 1.00 142.84 ? 326 ARG B NE 1 ATOM 5518 C CZ . ARG B 1 330 ? -28.300 -23.374 15.780 1.00 142.19 ? 326 ARG B CZ 1 ATOM 5519 N NH1 . ARG B 1 330 ? -28.174 -22.081 16.040 1.00 145.45 ? 326 ARG B NH1 1 ATOM 5520 N NH2 . ARG B 1 330 ? -28.160 -24.259 16.759 1.00 143.38 ? 326 ARG B NH2 1 ATOM 5521 N N . PRO B 1 331 ? -30.033 -25.172 9.709 1.00 147.46 ? 327 PRO B N 1 ATOM 5522 C CA . PRO B 1 331 ? -29.358 -24.512 8.582 1.00 146.80 ? 327 PRO B CA 1 ATOM 5523 C C . PRO B 1 331 ? -27.836 -24.417 8.683 1.00 149.94 ? 327 PRO B C 1 ATOM 5524 O O . PRO B 1 331 ? -27.281 -24.189 9.759 1.00 153.85 ? 327 PRO B O 1 ATOM 5525 C CB . PRO B 1 331 ? -29.970 -23.099 8.586 1.00 138.62 ? 327 PRO B CB 1 ATOM 5526 C CG . PRO B 1 331 ? -30.725 -22.980 9.885 1.00 131.48 ? 327 PRO B CG 1 ATOM 5527 C CD . PRO B 1 331 ? -31.167 -24.366 10.188 1.00 142.47 ? 327 PRO B CD 1 ATOM 5528 N N . ALA B 1 332 ? -27.181 -24.599 7.539 1.00 146.03 ? 328 ALA B N 1 ATOM 5529 C CA . ALA B 1 332 ? -25.751 -24.357 7.390 1.00 136.42 ? 328 ALA B CA 1 ATOM 5530 C C . ALA B 1 332 ? -25.527 -23.680 6.044 1.00 141.56 ? 328 ALA B C 1 ATOM 5531 O O . ALA B 1 332 ? -26.086 -24.108 5.034 1.00 148.09 ? 328 ALA B O 1 ATOM 5532 C CB . ALA B 1 332 ? -24.965 -25.651 7.482 1.00 123.26 ? 328 ALA B CB 1 ATOM 5533 N N . VAL B 1 333 ? -24.717 -22.625 6.027 1.00 140.48 ? 329 VAL B N 1 ATOM 5534 C CA . VAL B 1 333 ? -24.539 -21.828 4.817 1.00 143.46 ? 329 VAL B CA 1 ATOM 5535 C C . VAL B 1 333 ? -23.083 -21.426 4.610 1.00 139.50 ? 329 VAL B C 1 ATOM 5536 O O . VAL B 1 333 ? -22.336 -21.222 5.568 1.00 136.04 ? 329 VAL B O 1 ATOM 5537 C CB . VAL B 1 333 ? -25.415 -20.553 4.853 1.00 146.25 ? 329 VAL B CB 1 ATOM 5538 C CG1 . VAL B 1 333 ? -25.355 -19.818 3.517 1.00 152.69 ? 329 VAL B CG1 1 ATOM 5539 C CG2 . VAL B 1 333 ? -26.859 -20.906 5.198 1.00 145.14 ? 329 VAL B CG2 1 ATOM 5540 N N . PHE B 1 334 ? -22.695 -21.326 3.342 1.00 142.60 ? 330 PHE B N 1 ATOM 5541 C CA . PHE B 1 334 ? -21.356 -20.899 2.961 1.00 152.28 ? 330 PHE B CA 1 ATOM 5542 C C . PHE B 1 334 ? -21.420 -19.907 1.805 1.00 150.85 ? 330 PHE B C 1 ATOM 5543 O O . PHE B 1 334 ? -22.004 -20.196 0.759 1.00 160.46 ? 330 PHE B O 1 ATOM 5544 C CB . PHE B 1 334 ? -20.499 -22.105 2.573 1.00 144.54 ? 330 PHE B CB 1 ATOM 5545 C CG . PHE B 1 334 ? -20.270 -23.072 3.701 1.00 132.88 ? 330 PHE B CG 1 ATOM 5546 C CD1 . PHE B 1 334 ? -19.581 -22.682 4.837 1.00 139.20 ? 330 PHE B CD1 1 ATOM 5547 C CD2 . PHE B 1 334 ? -20.738 -24.374 3.622 1.00 129.49 ? 330 PHE B CD2 1 ATOM 5548 C CE1 . PHE B 1 334 ? -19.370 -23.568 5.875 1.00 132.68 ? 330 PHE B CE1 1 ATOM 5549 C CE2 . PHE B 1 334 ? -20.527 -25.264 4.658 1.00 130.65 ? 330 PHE B CE2 1 ATOM 5550 C CZ . PHE B 1 334 ? -19.841 -24.860 5.785 1.00 131.05 ? 330 PHE B CZ 1 ATOM 5551 N N . THR B 1 335 ? -20.820 -18.738 2.008 1.00 147.46 ? 331 THR B N 1 ATOM 5552 C CA . THR B 1 335 ? -20.748 -17.712 0.973 1.00 152.28 ? 331 THR B CA 1 ATOM 5553 C C . THR B 1 335 ? -19.304 -17.527 0.523 1.00 154.33 ? 331 THR B C 1 ATOM 5554 O O . THR B 1 335 ? -18.387 -17.482 1.345 1.00 146.02 ? 331 THR B O 1 ATOM 5555 C CB . THR B 1 335 ? -21.315 -16.361 1.461 1.00 145.89 ? 331 THR B CB 1 ATOM 5556 O OG1 . THR B 1 335 ? -21.105 -15.363 0.454 1.00 154.79 ? 331 THR B OG1 1 ATOM 5557 C CG2 . THR B 1 335 ? -20.648 -15.918 2.761 1.00 137.28 ? 331 THR B CG2 1 ATOM 5558 N N . CYS B 1 336 ? -19.112 -17.433 -0.788 1.00 152.11 ? 332 CYS B N 1 ATOM 5559 C CA . CYS B 1 336 ? -17.782 -17.284 -1.364 1.00 139.27 ? 332 CYS B CA 1 ATOM 5560 C C . CYS B 1 336 ? -17.479 -15.810 -1.618 1.00 129.18 ? 332 CYS B C 1 ATOM 5561 O O . CYS B 1 336 ? -18.091 -15.187 -2.486 1.00 133.13 ? 332 CYS B O 1 ATOM 5562 C CB . CYS B 1 336 ? -17.677 -18.083 -2.668 1.00 140.24 ? 332 CYS B CB 1 ATOM 5563 S SG . CYS B 1 336 ? -15.996 -18.560 -3.131 1.00 141.37 ? 332 CYS B SG 1 ATOM 5564 N N . GLN B 1 337 ? -16.535 -15.255 -0.861 1.00 122.79 ? 333 GLN B N 1 ATOM 5565 C CA . GLN B 1 337 ? -16.107 -13.878 -1.080 1.00 126.63 ? 333 GLN B CA 1 ATOM 5566 C C . GLN B 1 337 ? -15.034 -13.887 -2.155 1.00 117.30 ? 333 GLN B C 1 ATOM 5567 O O . GLN B 1 337 ? -13.964 -14.462 -1.960 1.00 113.95 ? 333 GLN B O 1 ATOM 5568 C CB . GLN B 1 337 ? -15.567 -13.240 0.204 1.00 131.39 ? 333 GLN B CB 1 ATOM 5569 C CG . GLN B 1 337 ? -16.305 -13.633 1.481 1.00 127.90 ? 333 GLN B CG 1 ATOM 5570 C CD . GLN B 1 337 ? -15.581 -14.694 2.296 1.00 124.27 ? 333 GLN B CD 1 ATOM 5571 O OE1 . GLN B 1 337 ? -16.202 -15.630 2.799 1.00 126.63 ? 333 GLN B OE1 1 ATOM 5572 N NE2 . GLN B 1 337 ? -14.269 -14.545 2.445 1.00 123.61 ? 333 GLN B NE2 1 ATOM 5573 N N . TYR B 1 338 ? -15.315 -13.237 -3.280 1.00 111.80 ? 334 TYR B N 1 ATOM 5574 C CA . TYR B 1 338 ? -14.451 -13.331 -4.450 1.00 100.46 ? 334 TYR B CA 1 ATOM 5575 C C . TYR B 1 338 ? -13.854 -11.990 -4.848 1.00 109.01 ? 334 TYR B C 1 ATOM 5576 O O . TYR B 1 338 ? -14.438 -10.932 -4.610 1.00 118.65 ? 334 TYR B O 1 ATOM 5577 C CB . TYR B 1 338 ? -15.228 -13.914 -5.631 1.00 96.71 ? 334 TYR B CB 1 ATOM 5578 C CG . TYR B 1 338 ? -16.564 -13.247 -5.876 1.00 108.65 ? 334 TYR B CG 1 ATOM 5579 C CD1 . TYR B 1 338 ? -16.646 -12.035 -6.545 1.00 119.13 ? 334 TYR B CD1 1 ATOM 5580 C CD2 . TYR B 1 338 ? -17.743 -13.831 -5.437 1.00 116.52 ? 334 TYR B CD2 1 ATOM 5581 C CE1 . TYR B 1 338 ? -17.864 -11.422 -6.771 1.00 125.40 ? 334 TYR B CE1 1 ATOM 5582 C CE2 . TYR B 1 338 ? -18.967 -13.226 -5.657 1.00 122.62 ? 334 TYR B CE2 1 ATOM 5583 C CZ . TYR B 1 338 ? -19.021 -12.022 -6.325 1.00 124.39 ? 334 TYR B CZ 1 ATOM 5584 O OH . TYR B 1 338 ? -20.237 -11.416 -6.547 1.00 123.82 ? 334 TYR B OH 1 ATOM 5585 N N . THR B 1 339 ? -12.675 -12.060 -5.455 1.00 104.85 ? 335 THR B N 1 ATOM 5586 C CA . THR B 1 339 ? -12.008 -10.896 -6.018 1.00 95.96 ? 335 THR B CA 1 ATOM 5587 C C . THR B 1 339 ? -11.316 -11.313 -7.306 1.00 85.33 ? 335 THR B C 1 ATOM 5588 O O . THR B 1 339 ? -11.508 -12.430 -7.790 1.00 88.88 ? 335 THR B O 1 ATOM 5589 C CB . THR B 1 339 ? -10.977 -10.291 -5.051 1.00 94.45 ? 335 THR B CB 1 ATOM 5590 O OG1 . THR B 1 339 ? -9.908 -11.221 -4.840 1.00 96.79 ? 335 THR B OG1 1 ATOM 5591 C CG2 . THR B 1 339 ? -11.622 -9.945 -3.718 1.00 114.02 ? 335 THR B CG2 1 ATOM 5592 N N . GLY B 1 340 ? -10.514 -10.412 -7.861 1.00 79.02 ? 336 GLY B N 1 ATOM 5593 C CA . GLY B 1 340 ? -9.829 -10.676 -9.111 1.00 92.59 ? 336 GLY B CA 1 ATOM 5594 C C . GLY B 1 340 ? -10.720 -10.299 -10.273 1.00 84.31 ? 336 GLY B C 1 ATOM 5595 O O . GLY B 1 340 ? -11.935 -10.183 -10.113 1.00 88.74 ? 336 GLY B O 1 ATOM 5596 N N . ASN B 1 341 ? -10.118 -10.098 -11.441 1.00 83.50 ? 337 ASN B N 1 ATOM 5597 C CA . ASN B 1 341 ? -10.873 -9.742 -12.635 1.00 80.79 ? 337 ASN B CA 1 ATOM 5598 C C . ASN B 1 341 ? -10.297 -10.430 -13.877 1.00 84.87 ? 337 ASN B C 1 ATOM 5599 O O . ASN B 1 341 ? -9.085 -10.604 -13.977 1.00 90.63 ? 337 ASN B O 1 ATOM 5600 C CB . ASN B 1 341 ? -10.872 -8.222 -12.819 1.00 88.84 ? 337 ASN B CB 1 ATOM 5601 C CG . ASN B 1 341 ? -11.970 -7.742 -13.747 1.00 89.63 ? 337 ASN B CG 1 ATOM 5602 O OD1 . ASN B 1 341 ? -13.140 -7.691 -13.366 1.00 83.61 ? 337 ASN B OD1 1 ATOM 5603 N ND2 . ASN B 1 341 ? -11.599 -7.378 -14.968 1.00 80.38 ? 337 ASN B ND2 1 ATOM 5604 N N . PRO B 1 342 ? -11.165 -10.865 -14.808 1.00 87.28 ? 338 PRO B N 1 ATOM 5605 C CA . PRO B 1 342 ? -12.619 -10.940 -14.647 1.00 85.58 ? 338 PRO B CA 1 ATOM 5606 C C . PRO B 1 342 ? -12.987 -12.094 -13.727 1.00 84.04 ? 338 PRO B C 1 ATOM 5607 O O . PRO B 1 342 ? -12.096 -12.827 -13.294 1.00 91.07 ? 338 PRO B O 1 ATOM 5608 C CB . PRO B 1 342 ? -13.118 -11.185 -16.070 1.00 87.35 ? 338 PRO B CB 1 ATOM 5609 C CG . PRO B 1 342 ? -12.005 -11.934 -16.720 1.00 75.48 ? 338 PRO B CG 1 ATOM 5610 C CD . PRO B 1 342 ? -10.736 -11.373 -16.124 1.00 84.08 ? 338 PRO B CD 1 ATOM 5611 N N . ILE B 1 343 ? -14.272 -12.249 -13.430 1.00 90.03 ? 339 ILE B N 1 ATOM 5612 C CA . ILE B 1 343 ? -14.748 -13.422 -12.710 1.00 90.90 ? 339 ILE B CA 1 ATOM 5613 C C . ILE B 1 343 ? -15.780 -14.114 -13.583 1.00 92.54 ? 339 ILE B C 1 ATOM 5614 O O . ILE B 1 343 ? -16.870 -13.592 -13.819 1.00 102.58 ? 339 ILE B O 1 ATOM 5615 C CB . ILE B 1 343 ? -15.336 -13.057 -11.338 1.00 94.41 ? 339 ILE B CB 1 ATOM 5616 C CG1 . ILE B 1 343 ? -14.281 -12.308 -10.517 1.00 99.82 ? 339 ILE B CG1 1 ATOM 5617 C CG2 . ILE B 1 343 ? -15.800 -14.317 -10.606 1.00 91.62 ? 339 ILE B CG2 1 ATOM 5618 C CD1 . ILE B 1 343 ? -14.741 -11.867 -9.153 1.00 98.28 ? 339 ILE B CD1 1 ATOM 5619 N N . LYS B 1 344 ? -15.418 -15.298 -14.060 1.00 93.77 ? 340 LYS B N 1 ATOM 5620 C CA . LYS B 1 344 ? -16.220 -16.013 -15.038 1.00 96.39 ? 340 LYS B CA 1 ATOM 5621 C C . LYS B 1 344 ? -17.290 -16.848 -14.352 1.00 93.48 ? 340 LYS B C 1 ATOM 5622 O O . LYS B 1 344 ? -18.476 -16.523 -14.418 1.00 93.09 ? 340 LYS B O 1 ATOM 5623 C CB . LYS B 1 344 ? -15.324 -16.901 -15.900 1.00 96.29 ? 340 LYS B CB 1 ATOM 5624 C CG . LYS B 1 344 ? -16.040 -17.624 -17.026 1.00 99.71 ? 340 LYS B CG 1 ATOM 5625 C CD . LYS B 1 344 ? -15.593 -17.109 -18.382 1.00 103.58 ? 340 LYS B CD 1 ATOM 5626 C CE . LYS B 1 344 ? -16.006 -18.056 -19.493 1.00 117.58 ? 340 LYS B CE 1 ATOM 5627 N NZ . LYS B 1 344 ? -17.477 -18.279 -19.528 1.00 131.39 ? 340 LYS B NZ 1 ATOM 5628 N N . THR B 1 345 ? -16.865 -17.923 -13.695 1.00 96.08 ? 341 THR B N 1 ATOM 5629 C CA . THR B 1 345 ? -17.795 -18.820 -13.022 1.00 102.32 ? 341 THR B CA 1 ATOM 5630 C C . THR B 1 345 ? -17.256 -19.341 -11.697 1.00 104.13 ? 341 THR B C 1 ATOM 5631 O O . THR B 1 345 ? -16.130 -19.831 -11.618 1.00 104.49 ? 341 THR B O 1 ATOM 5632 C CB . THR B 1 345 ? -18.144 -20.028 -13.911 1.00 101.77 ? 341 THR B CB 1 ATOM 5633 O OG1 . THR B 1 345 ? -16.939 -20.628 -14.403 1.00 92.05 ? 341 THR B OG1 1 ATOM 5634 C CG2 . THR B 1 345 ? -19.013 -19.597 -15.083 1.00 109.25 ? 341 THR B CG2 1 ATOM 5635 N N . VAL B 1 346 ? -18.077 -19.223 -10.660 1.00 110.35 ? 342 VAL B N 1 ATOM 5636 C CA . VAL B 1 346 ? -17.832 -19.903 -9.397 1.00 119.04 ? 342 VAL B CA 1 ATOM 5637 C C . VAL B 1 346 ? -18.386 -21.319 -9.508 1.00 131.54 ? 342 VAL B C 1 ATOM 5638 O O . VAL B 1 346 ? -19.386 -21.542 -10.190 1.00 142.59 ? 342 VAL B O 1 ATOM 5639 C CB . VAL B 1 346 ? -18.482 -19.166 -8.205 1.00 131.88 ? 342 VAL B CB 1 ATOM 5640 C CG1 . VAL B 1 346 ? -20.002 -19.102 -8.366 1.00 149.20 ? 342 VAL B CG1 1 ATOM 5641 C CG2 . VAL B 1 346 ? -18.098 -19.835 -6.889 1.00 132.29 ? 342 VAL B CG2 1 ATOM 5642 N N . SER B 1 347 ? -17.734 -22.273 -8.852 1.00 127.32 ? 343 SER B N 1 ATOM 5643 C CA . SER B 1 347 ? -18.199 -23.656 -8.863 1.00 129.77 ? 343 SER B CA 1 ATOM 5644 C C . SER B 1 347 ? -17.980 -24.322 -7.510 1.00 123.23 ? 343 SER B C 1 ATOM 5645 O O . SER B 1 347 ? -16.948 -24.128 -6.867 1.00 122.93 ? 343 SER B O 1 ATOM 5646 C CB . SER B 1 347 ? -17.494 -24.451 -9.965 1.00 124.52 ? 343 SER B CB 1 ATOM 5647 O OG . SER B 1 347 ? -16.092 -24.470 -9.769 1.00 130.23 ? 343 SER B OG 1 ATOM 5648 N N . TRP B 1 348 ? -18.965 -25.112 -7.093 1.00 127.76 ? 344 TRP B N 1 ATOM 5649 C CA . TRP B 1 348 ? -18.918 -25.822 -5.821 1.00 130.13 ? 344 TRP B CA 1 ATOM 5650 C C . TRP B 1 348 ? -18.627 -27.296 -6.048 1.00 131.09 ? 344 TRP B C 1 ATOM 5651 O O . TRP B 1 348 ? -19.013 -27.865 -7.069 1.00 134.58 ? 344 TRP B O 1 ATOM 5652 C CB . TRP B 1 348 ? -20.237 -25.661 -5.066 1.00 126.48 ? 344 TRP B CB 1 ATOM 5653 C CG . TRP B 1 348 ? -20.518 -24.249 -4.658 1.00 143.38 ? 344 TRP B CG 1 ATOM 5654 C CD1 . TRP B 1 348 ? -21.115 -23.282 -5.411 1.00 152.17 ? 344 TRP B CD1 1 ATOM 5655 C CD2 . TRP B 1 348 ? -20.213 -23.643 -3.397 1.00 137.54 ? 344 TRP B CD2 1 ATOM 5656 N NE1 . TRP B 1 348 ? -21.200 -22.111 -4.699 1.00 158.18 ? 344 TRP B NE1 1 ATOM 5657 C CE2 . TRP B 1 348 ? -20.653 -22.307 -3.458 1.00 145.03 ? 344 TRP B CE2 1 ATOM 5658 C CE3 . TRP B 1 348 ? -19.611 -24.101 -2.222 1.00 132.58 ? 344 TRP B CE3 1 ATOM 5659 C CZ2 . TRP B 1 348 ? -20.509 -21.424 -2.391 1.00 148.55 ? 344 TRP B CZ2 1 ATOM 5660 C CZ3 . TRP B 1 348 ? -19.469 -23.224 -1.164 1.00 134.65 ? 344 TRP B CZ3 1 ATOM 5661 C CH2 . TRP B 1 348 ? -19.916 -21.901 -1.255 1.00 139.20 ? 344 TRP B CH2 1 ATOM 5662 N N . MET B 1 349 ? -17.921 -27.906 -5.103 1.00 135.62 ? 345 MET B N 1 ATOM 5663 C CA . MET B 1 349 ? -17.656 -29.336 -5.152 1.00 122.95 ? 345 MET B CA 1 ATOM 5664 C C . MET B 1 349 ? -17.580 -29.920 -3.746 1.00 113.08 ? 345 MET B C 1 ATOM 5665 O O . MET B 1 349 ? -17.028 -29.302 -2.834 1.00 104.05 ? 345 MET B O 1 ATOM 5666 C CB . MET B 1 349 ? -16.360 -29.611 -5.919 1.00 122.12 ? 345 MET B CB 1 ATOM 5667 C CG . MET B 1 349 ? -15.198 -28.710 -5.536 1.00 125.73 ? 345 MET B CG 1 ATOM 5668 S SD . MET B 1 349 ? -13.749 -28.963 -6.579 1.00 125.99 ? 345 MET B SD 1 ATOM 5669 C CE . MET B 1 349 ? -14.319 -28.284 -8.136 1.00 118.71 ? 345 MET B CE 1 ATOM 5670 N N . LYS B 1 350 ? -18.140 -31.116 -3.582 1.00 121.47 ? 346 LYS B N 1 ATOM 5671 C CA . LYS B 1 350 ? -18.121 -31.811 -2.301 1.00 120.91 ? 346 LYS B CA 1 ATOM 5672 C C . LYS B 1 350 ? -17.032 -32.876 -2.311 1.00 122.41 ? 346 LYS B C 1 ATOM 5673 O O . LYS B 1 350 ? -17.146 -33.886 -3.006 1.00 123.71 ? 346 LYS B O 1 ATOM 5674 C CB . LYS B 1 350 ? -19.483 -32.447 -2.010 1.00 124.09 ? 346 LYS B CB 1 ATOM 5675 C CG . LYS B 1 350 ? -19.568 -33.164 -0.671 1.00 119.34 ? 346 LYS B CG 1 ATOM 5676 C CD . LYS B 1 350 ? -20.853 -33.968 -0.548 1.00 121.12 ? 346 LYS B CD 1 ATOM 5677 C CE . LYS B 1 350 ? -21.029 -34.539 0.853 1.00 118.55 ? 346 LYS B CE 1 ATOM 5678 N NZ . LYS B 1 350 ? -19.835 -35.297 1.324 1.00 113.82 ? 346 LYS B NZ 1 ATOM 5679 N N . ASP B 1 351 ? -15.982 -32.639 -1.530 1.00 118.67 ? 347 ASP B N 1 ATOM 5680 C CA . ASP B 1 351 ? -14.854 -33.562 -1.432 1.00 110.97 ? 347 ASP B CA 1 ATOM 5681 C C . ASP B 1 351 ? -14.252 -33.868 -2.802 1.00 104.65 ? 347 ASP B C 1 ATOM 5682 O O . ASP B 1 351 ? -13.735 -34.961 -3.034 1.00 105.25 ? 347 ASP B O 1 ATOM 5683 C CB . ASP B 1 351 ? -15.287 -34.860 -0.747 1.00 115.80 ? 347 ASP B CB 1 ATOM 5684 C CG . ASP B 1 351 ? -15.895 -34.623 0.622 1.00 119.80 ? 347 ASP B CG 1 ATOM 5685 O OD1 . ASP B 1 351 ? -15.162 -34.184 1.531 1.00 120.46 ? 347 ASP B OD1 1 ATOM 5686 O OD2 . ASP B 1 351 ? -17.105 -34.882 0.794 1.00 121.70 ? 347 ASP B OD2 1 ATOM 5687 N N . GLY B 1 352 ? -14.326 -32.893 -3.703 1.00 103.06 ? 348 GLY B N 1 ATOM 5688 C CA . GLY B 1 352 ? -13.776 -33.032 -5.038 1.00 103.38 ? 348 GLY B CA 1 ATOM 5689 C C . GLY B 1 352 ? -14.808 -33.504 -6.043 1.00 113.38 ? 348 GLY B C 1 ATOM 5690 O O . GLY B 1 352 ? -14.648 -33.305 -7.249 1.00 110.20 ? 348 GLY B O 1 ATOM 5691 N N . LYS B 1 353 ? -15.872 -34.130 -5.549 1.00 118.44 ? 349 LYS B N 1 ATOM 5692 C CA . LYS B 1 353 ? -16.990 -34.515 -6.400 1.00 110.85 ? 349 LYS B CA 1 ATOM 5693 C C . LYS B 1 353 ? -17.628 -33.248 -6.952 1.00 118.38 ? 349 LYS B C 1 ATOM 5694 O O . LYS B 1 353 ? -17.795 -32.271 -6.222 1.00 118.32 ? 349 LYS B O 1 ATOM 5695 C CB . LYS B 1 353 ? -18.020 -35.338 -5.624 1.00 104.25 ? 349 LYS B CB 1 ATOM 5696 C CG . LYS B 1 353 ? -18.736 -36.381 -6.467 1.00 112.97 ? 349 LYS B CG 1 ATOM 5697 C CD . LYS B 1 353 ? -20.121 -36.688 -5.919 1.00 122.08 ? 349 LYS B CD 1 ATOM 5698 C CE . LYS B 1 353 ? -20.940 -37.508 -6.903 1.00 130.07 ? 349 LYS B CE 1 ATOM 5699 N NZ . LYS B 1 353 ? -22.403 -37.328 -6.692 1.00 119.39 ? 349 LYS B NZ 1 ATOM 5700 N N . ALA B 1 354 ? -18.002 -33.263 -8.227 1.00 122.32 ? 350 ALA B N 1 ATOM 5701 C CA . ALA B 1 354 ? -18.521 -32.061 -8.864 1.00 114.27 ? 350 ALA B CA 1 ATOM 5702 C C . ALA B 1 354 ? -20.032 -32.000 -8.701 1.00 118.90 ? 350 ALA B C 1 ATOM 5703 O O . ALA B 1 354 ? -20.764 -32.801 -9.284 1.00 118.18 ? 350 ALA B O 1 ATOM 5704 C CB . ALA B 1 354 ? -18.140 -32.030 -10.339 1.00 105.85 ? 350 ALA B CB 1 ATOM 5705 N N . ILE B 1 355 ? -20.487 -31.039 -7.901 1.00 131.23 ? 351 ILE B N 1 ATOM 5706 C CA . ILE B 1 355 ? -21.912 -30.816 -7.690 1.00 142.37 ? 351 ILE B CA 1 ATOM 5707 C C . ILE B 1 355 ? -22.193 -29.336 -7.964 1.00 139.51 ? 351 ILE B C 1 ATOM 5708 O O . ILE B 1 355 ? -21.689 -28.444 -7.283 1.00 134.75 ? 351 ILE B O 1 ATOM 5709 C CB . ILE B 1 355 ? -22.354 -31.261 -6.260 1.00 125.43 ? 351 ILE B CB 1 ATOM 5710 C CG1 . ILE B 1 355 ? -21.886 -30.278 -5.176 1.00 124.82 ? 351 ILE B CG1 1 ATOM 5711 C CG2 . ILE B 1 355 ? -21.833 -32.678 -5.984 1.00 121.17 ? 351 ILE B CG2 1 ATOM 5712 C CD1 . ILE B 1 355 ? -22.152 -30.736 -3.755 1.00 110.02 ? 351 ILE B CD1 1 ATOM 5713 N N . GLY B 1 356 ? -22.960 -29.086 -9.017 1.00 133.34 ? 352 GLY B N 1 ATOM 5714 C CA . GLY B 1 356 ? -23.119 -27.742 -9.534 1.00 149.19 ? 352 GLY B CA 1 ATOM 5715 C C . GLY B 1 356 ? -23.992 -26.803 -8.729 1.00 179.94 ? 352 GLY B C 1 ATOM 5716 O O . GLY B 1 356 ? -25.112 -27.144 -8.347 1.00 189.20 ? 352 GLY B O 1 ATOM 5717 N N . HIS B 1 357 ? -23.462 -25.615 -8.461 1.00 164.77 ? 353 HIS B N 1 ATOM 5718 C CA . HIS B 1 357 ? -24.288 -24.449 -8.190 1.00 175.03 ? 353 HIS B CA 1 ATOM 5719 C C . HIS B 1 357 ? -23.524 -23.210 -8.646 1.00 178.06 ? 353 HIS B C 1 ATOM 5720 O O . HIS B 1 357 ? -22.312 -23.113 -8.452 1.00 161.76 ? 353 HIS B O 1 ATOM 5721 C CB . HIS B 1 357 ? -24.666 -24.346 -6.712 1.00 170.66 ? 353 HIS B CB 1 ATOM 5722 C CG . HIS B 1 357 ? -25.871 -23.495 -6.464 1.00 188.67 ? 353 HIS B CG 1 ATOM 5723 N ND1 . HIS B 1 357 ? -27.053 -23.661 -7.158 1.00 179.25 ? 353 HIS B ND1 1 ATOM 5724 C CD2 . HIS B 1 357 ? -26.082 -22.466 -5.611 1.00 196.14 ? 353 HIS B CD2 1 ATOM 5725 C CE1 . HIS B 1 357 ? -27.936 -22.775 -6.740 1.00 191.83 ? 353 HIS B CE1 1 ATOM 5726 N NE2 . HIS B 1 357 ? -27.373 -22.037 -5.798 1.00 201.47 ? 353 HIS B NE2 1 ATOM 5727 N N . SER B 1 358 ? -24.241 -22.268 -9.248 1.00 192.14 ? 354 SER B N 1 ATOM 5728 C CA . SER B 1 358 ? -23.627 -21.077 -9.827 1.00 183.17 ? 354 SER B CA 1 ATOM 5729 C C . SER B 1 358 ? -23.689 -19.880 -8.883 1.00 188.74 ? 354 SER B C 1 ATOM 5730 O O . SER B 1 358 ? -23.181 -18.805 -9.203 1.00 187.58 ? 354 SER B O 1 ATOM 5731 C CB . SER B 1 358 ? -24.308 -20.730 -11.152 1.00 192.74 ? 354 SER B CB 1 ATOM 5732 O OG . SER B 1 358 ? -25.709 -20.593 -10.985 1.00 232.52 ? 354 SER B OG 1 ATOM 5733 N N . GLU B 1 359 ? -24.307 -20.070 -7.722 1.00 202.87 ? 355 GLU B N 1 ATOM 5734 C CA . GLU B 1 359 ? -24.519 -18.977 -6.780 1.00 213.33 ? 355 GLU B CA 1 ATOM 5735 C C . GLU B 1 359 ? -23.320 -18.822 -5.843 1.00 200.79 ? 355 GLU B C 1 ATOM 5736 O O . GLU B 1 359 ? -22.760 -19.818 -5.387 1.00 194.12 ? 355 GLU B O 1 ATOM 5737 C CB . GLU B 1 359 ? -25.794 -19.221 -5.969 1.00 277.71 ? 355 GLU B CB 1 ATOM 5738 C CG . GLU B 1 359 ? -26.372 -17.978 -5.314 1.00 308.65 ? 355 GLU B CG 1 ATOM 5739 C CD . GLU B 1 359 ? -27.658 -18.262 -4.560 1.00 338.55 ? 355 GLU B CD 1 ATOM 5740 O OE1 . GLU B 1 359 ? -28.148 -19.409 -4.626 1.00 367.60 ? 355 GLU B OE1 1 ATOM 5741 O OE2 . GLU B 1 359 ? -28.178 -17.339 -3.899 1.00 331.02 ? 355 GLU B OE2 1 ATOM 5742 N N . PRO B 1 360 ? -22.916 -17.572 -5.554 1.00 197.65 ? 356 PRO B N 1 ATOM 5743 C CA . PRO B 1 360 ? -21.829 -17.368 -4.589 1.00 179.81 ? 356 PRO B CA 1 ATOM 5744 C C . PRO B 1 360 ? -22.226 -17.811 -3.185 1.00 178.99 ? 356 PRO B C 1 ATOM 5745 O O . PRO B 1 360 ? -21.362 -18.160 -2.380 1.00 162.87 ? 356 PRO B O 1 ATOM 5746 C CB . PRO B 1 360 ? -21.589 -15.855 -4.642 1.00 166.70 ? 356 PRO B CB 1 ATOM 5747 C CG . PRO B 1 360 ? -22.879 -15.284 -5.119 1.00 185.62 ? 356 PRO B CG 1 ATOM 5748 C CD . PRO B 1 360 ? -23.428 -16.294 -6.078 1.00 197.95 ? 356 PRO B CD 1 ATOM 5749 N N . VAL B 1 361 ? -23.527 -17.797 -2.913 1.00 199.18 ? 357 VAL B N 1 ATOM 5750 C CA . VAL B 1 361 ? -24.064 -18.196 -1.617 1.00 196.62 ? 357 VAL B CA 1 ATOM 5751 C C . VAL B 1 361 ? -24.876 -19.479 -1.755 1.00 194.87 ? 357 VAL B C 1 ATOM 5752 O O . VAL B 1 361 ? -25.945 -19.480 -2.367 1.00 208.70 ? 357 VAL B O 1 ATOM 5753 C CB . VAL B 1 361 ? -24.959 -17.095 -1.009 1.00 195.61 ? 357 VAL B CB 1 ATOM 5754 C CG1 . VAL B 1 361 ? -25.293 -17.420 0.443 1.00 174.72 ? 357 VAL B CG1 1 ATOM 5755 C CG2 . VAL B 1 361 ? -24.280 -15.735 -1.113 1.00 173.01 ? 357 VAL B CG2 1 ATOM 5756 N N . LEU B 1 362 ? -24.362 -20.566 -1.186 1.00 170.49 ? 358 LEU B N 1 ATOM 5757 C CA . LEU B 1 362 ? -25.057 -21.849 -1.200 1.00 168.26 ? 358 LEU B CA 1 ATOM 5758 C C . LEU B 1 362 ? -25.387 -22.279 0.224 1.00 164.18 ? 358 LEU B C 1 ATOM 5759 O O . LEU B 1 362 ? -24.559 -22.167 1.130 1.00 163.45 ? 358 LEU B O 1 ATOM 5760 C CB . LEU B 1 362 ? -24.215 -22.915 -1.903 1.00 166.23 ? 358 LEU B CB 1 ATOM 5761 C CG . LEU B 1 362 ? -24.817 -24.321 -2.002 1.00 173.48 ? 358 LEU B CG 1 ATOM 5762 C CD1 . LEU B 1 362 ? -26.243 -24.309 -2.544 1.00 171.19 ? 358 LEU B CD1 1 ATOM 5763 C CD2 . LEU B 1 362 ? -23.936 -25.190 -2.883 1.00 185.13 ? 358 LEU B CD2 1 ATOM 5764 N N . ARG B 1 363 ? -26.609 -22.772 0.404 1.00 170.65 ? 359 ARG B N 1 ATOM 5765 C CA . ARG B 1 363 ? -27.146 -23.099 1.717 1.00 164.13 ? 359 ARG B CA 1 ATOM 5766 C C . ARG B 1 363 ? -27.758 -24.494 1.740 1.00 156.47 ? 359 ARG B C 1 ATOM 5767 O O . ARG B 1 363 ? -28.272 -24.970 0.726 1.00 157.42 ? 359 ARG B O 1 ATOM 5768 C CB . ARG B 1 363 ? -28.203 -22.069 2.112 1.00 174.05 ? 359 ARG B CB 1 ATOM 5769 C CG . ARG B 1 363 ? -29.238 -21.830 1.020 1.00 179.76 ? 359 ARG B CG 1 ATOM 5770 C CD . ARG B 1 363 ? -30.286 -20.814 1.433 1.00 175.13 ? 359 ARG B CD 1 ATOM 5771 N NE . ARG B 1 363 ? -29.697 -19.522 1.775 1.00 166.72 ? 359 ARG B NE 1 ATOM 5772 C CZ . ARG B 1 363 ? -29.245 -18.643 0.885 1.00 169.42 ? 359 ARG B CZ 1 ATOM 5773 N NH1 . ARG B 1 363 ? -29.300 -18.910 -0.413 1.00 184.37 ? 359 ARG B NH1 1 ATOM 5774 N NH2 . ARG B 1 363 ? -28.727 -17.494 1.294 1.00 166.39 ? 359 ARG B NH2 1 ATOM 5775 N N . ILE B 1 364 ? -27.690 -25.145 2.897 1.00 148.38 ? 360 ILE B N 1 ATOM 5776 C CA . ILE B 1 364 ? -28.430 -26.380 3.127 1.00 149.33 ? 360 ILE B CA 1 ATOM 5777 C C . ILE B 1 364 ? -29.222 -26.265 4.432 1.00 157.06 ? 360 ILE B C 1 ATOM 5778 O O . ILE B 1 364 ? -28.650 -26.215 5.522 1.00 151.57 ? 360 ILE B O 1 ATOM 5779 C CB . ILE B 1 364 ? -27.488 -27.610 3.166 1.00 143.59 ? 360 ILE B CB 1 ATOM 5780 C CG1 . ILE B 1 364 ? -26.366 -27.431 4.194 1.00 135.64 ? 360 ILE B CG1 1 ATOM 5781 C CG2 . ILE B 1 364 ? -26.874 -27.848 1.793 1.00 132.68 ? 360 ILE B CG2 1 ATOM 5782 C CD1 . ILE B 1 364 ? -26.405 -28.447 5.313 1.00 132.49 ? 360 ILE B CD1 1 ATOM 5783 N N . GLU B 1 365 ? -30.546 -26.212 4.308 1.00 161.18 ? 361 GLU B N 1 ATOM 5784 C CA . GLU B 1 365 ? -31.426 -26.110 5.470 1.00 155.01 ? 361 GLU B CA 1 ATOM 5785 C C . GLU B 1 365 ? -31.884 -27.488 5.934 1.00 152.96 ? 361 GLU B C 1 ATOM 5786 O O . GLU B 1 365 ? -32.469 -27.626 7.009 1.00 155.89 ? 361 GLU B O 1 ATOM 5787 C CB . GLU B 1 365 ? -32.641 -25.227 5.160 1.00 154.75 ? 361 GLU B CB 1 ATOM 5788 C CG . GLU B 1 365 ? -33.564 -25.749 4.059 1.00 164.14 ? 361 GLU B CG 1 ATOM 5789 C CD . GLU B 1 365 ? -33.070 -25.439 2.658 1.00 165.75 ? 361 GLU B CD 1 ATOM 5790 O OE1 . GLU B 1 365 ? -31.981 -24.841 2.520 1.00 167.43 ? 361 GLU B OE1 1 ATOM 5791 O OE2 . GLU B 1 365 ? -33.774 -25.797 1.690 1.00 173.47 ? 361 GLU B OE2 1 ATOM 5792 N N . SER B 1 366 ? -31.614 -28.501 5.115 1.00 152.48 ? 362 SER B N 1 ATOM 5793 C CA . SER B 1 366 ? -31.906 -29.885 5.469 1.00 154.97 ? 362 SER B CA 1 ATOM 5794 C C . SER B 1 366 ? -30.645 -30.713 5.292 1.00 155.40 ? 362 SER B C 1 ATOM 5795 O O . SER B 1 366 ? -30.169 -30.902 4.172 1.00 161.18 ? 362 SER B O 1 ATOM 5796 C CB . SER B 1 366 ? -33.041 -30.446 4.611 1.00 159.01 ? 362 SER B CB 1 ATOM 5797 O OG . SER B 1 366 ? -33.306 -31.797 4.944 1.00 146.66 ? 362 SER B OG 1 ATOM 5798 N N . VAL B 1 367 ? -30.113 -31.210 6.404 1.00 161.92 ? 363 VAL B N 1 ATOM 5799 C CA . VAL B 1 367 ? -28.854 -31.938 6.389 1.00 156.35 ? 363 VAL B CA 1 ATOM 5800 C C . VAL B 1 367 ? -29.140 -33.436 6.415 1.00 152.54 ? 363 VAL B C 1 ATOM 5801 O O . VAL B 1 367 ? -30.014 -33.902 7.149 1.00 156.76 ? 363 VAL B O 1 ATOM 5802 C CB . VAL B 1 367 ? -27.934 -31.528 7.583 1.00 152.57 ? 363 VAL B CB 1 ATOM 5803 C CG1 . VAL B 1 367 ? -28.293 -30.132 8.091 1.00 148.94 ? 363 VAL B CG1 1 ATOM 5804 C CG2 . VAL B 1 367 ? -27.989 -32.538 8.728 1.00 146.60 ? 363 VAL B CG2 1 ATOM 5805 N N . LYS B 1 368 ? -28.417 -34.179 5.585 1.00 150.53 ? 364 LYS B N 1 ATOM 5806 C CA . LYS B 1 368 ? -28.500 -35.633 5.583 1.00 143.79 ? 364 LYS B CA 1 ATOM 5807 C C . LYS B 1 368 ? -27.418 -36.193 6.499 1.00 144.49 ? 364 LYS B C 1 ATOM 5808 O O . LYS B 1 368 ? -26.665 -35.440 7.115 1.00 153.26 ? 364 LYS B O 1 ATOM 5809 C CB . LYS B 1 368 ? -28.354 -36.182 4.161 1.00 139.19 ? 364 LYS B CB 1 ATOM 5810 C CG . LYS B 1 368 ? -29.498 -35.797 3.231 1.00 128.35 ? 364 LYS B CG 1 ATOM 5811 C CD . LYS B 1 368 ? -29.275 -36.325 1.822 1.00 128.72 ? 364 LYS B CD 1 ATOM 5812 C CE . LYS B 1 368 ? -30.418 -35.940 0.895 1.00 116.52 ? 364 LYS B CE 1 ATOM 5813 N NZ . LYS B 1 368 ? -30.190 -36.403 -0.503 1.00 125.52 ? 364 LYS B NZ 1 ATOM 5814 N N . LYS B 1 369 ? -27.352 -37.514 6.596 1.00 140.59 ? 365 LYS B N 1 ATOM 5815 C CA . LYS B 1 369 ? -26.348 -38.170 7.422 1.00 140.21 ? 365 LYS B CA 1 ATOM 5816 C C . LYS B 1 369 ? -24.993 -38.188 6.719 1.00 137.93 ? 365 LYS B C 1 ATOM 5817 O O . LYS B 1 369 ? -23.944 -38.219 7.363 1.00 126.93 ? 365 LYS B O 1 ATOM 5818 C CB . LYS B 1 369 ? -26.793 -39.595 7.750 1.00 128.14 ? 365 LYS B CB 1 ATOM 5819 C CG . LYS B 1 369 ? -25.831 -40.363 8.634 1.00 131.58 ? 365 LYS B CG 1 ATOM 5820 C CD . LYS B 1 369 ? -26.321 -41.778 8.870 1.00 124.40 ? 365 LYS B CD 1 ATOM 5821 C CE . LYS B 1 369 ? -25.324 -42.574 9.689 1.00 103.23 ? 365 LYS B CE 1 ATOM 5822 N NZ . LYS B 1 369 ? -25.103 -41.964 11.030 1.00 111.28 ? 365 LYS B NZ 1 ATOM 5823 N N . GLU B 1 370 ? -25.035 -38.157 5.391 1.00 139.75 ? 366 GLU B N 1 ATOM 5824 C CA . GLU B 1 370 ? -23.851 -38.362 4.561 1.00 136.17 ? 366 GLU B CA 1 ATOM 5825 C C . GLU B 1 370 ? -23.187 -37.055 4.113 1.00 135.71 ? 366 GLU B C 1 ATOM 5826 O O . GLU B 1 370 ? -22.217 -37.079 3.354 1.00 129.89 ? 366 GLU B O 1 ATOM 5827 C CB . GLU B 1 370 ? -24.218 -39.213 3.336 1.00 138.79 ? 366 GLU B CB 1 ATOM 5828 C CG . GLU B 1 370 ? -25.459 -38.754 2.570 1.00 141.60 ? 366 GLU B CG 1 ATOM 5829 C CD . GLU B 1 370 ? -25.918 -39.770 1.543 1.00 135.85 ? 366 GLU B CD 1 ATOM 5830 O OE1 . GLU B 1 370 ? -27.032 -39.608 1.000 1.00 129.27 ? 366 GLU B OE1 1 ATOM 5831 O OE2 . GLU B 1 370 ? -25.170 -40.736 1.282 1.00 143.17 ? 366 GLU B OE2 1 ATOM 5832 N N . ASP B 1 371 ? -23.700 -35.923 4.586 1.00 136.65 ? 367 ASP B N 1 ATOM 5833 C CA . ASP B 1 371 ? -23.155 -34.622 4.200 1.00 132.62 ? 367 ASP B CA 1 ATOM 5834 C C . ASP B 1 371 ? -21.952 -34.232 5.059 1.00 135.46 ? 367 ASP B C 1 ATOM 5835 O O . ASP B 1 371 ? -21.380 -33.155 4.885 1.00 131.20 ? 367 ASP B O 1 ATOM 5836 C CB . ASP B 1 371 ? -24.237 -33.536 4.284 1.00 137.10 ? 367 ASP B CB 1 ATOM 5837 C CG . ASP B 1 371 ? -24.917 -33.479 5.638 1.00 147.74 ? 367 ASP B CG 1 ATOM 5838 O OD1 . ASP B 1 371 ? -24.266 -33.774 6.662 1.00 139.89 ? 367 ASP B OD1 1 ATOM 5839 O OD2 . ASP B 1 371 ? -26.115 -33.130 5.674 1.00 156.13 ? 367 ASP B OD2 1 ATOM 5840 N N . LYS B 1 372 ? -21.569 -35.109 5.983 1.00 142.42 ? 368 LYS B N 1 ATOM 5841 C CA . LYS B 1 372 ? -20.393 -34.872 6.812 1.00 133.62 ? 368 LYS B CA 1 ATOM 5842 C C . LYS B 1 372 ? -19.147 -34.961 5.940 1.00 124.34 ? 368 LYS B C 1 ATOM 5843 O O . LYS B 1 372 ? -18.916 -35.974 5.280 1.00 121.66 ? 368 LYS B O 1 ATOM 5844 C CB . LYS B 1 372 ? -20.315 -35.892 7.954 1.00 129.50 ? 368 LYS B CB 1 ATOM 5845 C CG . LYS B 1 372 ? -19.619 -35.395 9.221 1.00 128.51 ? 368 LYS B CG 1 ATOM 5846 C CD . LYS B 1 372 ? -18.277 -34.746 8.929 1.00 131.12 ? 368 LYS B CD 1 ATOM 5847 C CE . LYS B 1 372 ? -17.525 -34.424 10.209 1.00 126.67 ? 368 LYS B CE 1 ATOM 5848 N NZ . LYS B 1 372 ? -16.328 -33.579 9.950 1.00 113.33 ? 368 LYS B NZ 1 ATOM 5849 N N . GLY B 1 373 ? -18.347 -33.899 5.939 1.00 118.65 ? 369 GLY B N 1 ATOM 5850 C CA . GLY B 1 373 ? -17.113 -33.883 5.177 1.00 123.89 ? 369 GLY B CA 1 ATOM 5851 C C . GLY B 1 373 ? -16.694 -32.496 4.727 1.00 124.60 ? 369 GLY B C 1 ATOM 5852 O O . GLY B 1 373 ? -17.254 -31.491 5.165 1.00 121.39 ? 369 GLY B O 1 ATOM 5853 N N . MET B 1 374 ? -15.700 -32.449 3.844 1.00 123.49 ? 370 MET B N 1 ATOM 5854 C CA . MET B 1 374 ? -15.175 -31.189 3.330 1.00 118.55 ? 370 MET B CA 1 ATOM 5855 C C . MET B 1 374 ? -16.073 -30.585 2.254 1.00 115.67 ? 370 MET B C 1 ATOM 5856 O O . MET B 1 374 ? -16.839 -31.291 1.597 1.00 130.23 ? 370 MET B O 1 ATOM 5857 C CB . MET B 1 374 ? -13.766 -31.388 2.760 1.00 119.69 ? 370 MET B CB 1 ATOM 5858 C CG . MET B 1 374 ? -12.656 -31.514 3.798 1.00 125.80 ? 370 MET B CG 1 ATOM 5859 S SD . MET B 1 374 ? -12.585 -30.148 4.976 1.00 148.60 ? 370 MET B SD 1 ATOM 5860 C CE . MET B 1 374 ? -12.614 -28.724 3.889 1.00 109.38 ? 370 MET B CE 1 ATOM 5861 N N . TYR B 1 375 ? -15.968 -29.269 2.093 1.00 108.92 ? 371 TYR B N 1 ATOM 5862 C CA . TYR B 1 375 ? -16.667 -28.544 1.039 1.00 117.04 ? 371 TYR B CA 1 ATOM 5863 C C . TYR B 1 375 ? -15.754 -27.451 0.490 1.00 109.46 ? 371 TYR B C 1 ATOM 5864 O O . TYR B 1 375 ? -14.941 -26.891 1.226 1.00 108.25 ? 371 TYR B O 1 ATOM 5865 C CB . TYR B 1 375 ? -17.972 -27.941 1.564 1.00 122.71 ? 371 TYR B CB 1 ATOM 5866 C CG . TYR B 1 375 ? -19.039 -28.967 1.881 1.00 122.93 ? 371 TYR B CG 1 ATOM 5867 C CD1 . TYR B 1 375 ? -19.111 -29.562 3.133 1.00 126.13 ? 371 TYR B CD1 1 ATOM 5868 C CD2 . TYR B 1 375 ? -19.976 -29.338 0.927 1.00 119.65 ? 371 TYR B CD2 1 ATOM 5869 C CE1 . TYR B 1 375 ? -20.085 -30.499 3.424 1.00 123.47 ? 371 TYR B CE1 1 ATOM 5870 C CE2 . TYR B 1 375 ? -20.953 -30.273 1.210 1.00 122.43 ? 371 TYR B CE2 1 ATOM 5871 C CZ . TYR B 1 375 ? -21.003 -30.849 2.458 1.00 124.88 ? 371 TYR B CZ 1 ATOM 5872 O OH . TYR B 1 375 ? -21.974 -31.780 2.740 1.00 130.21 ? 371 TYR B OH 1 ATOM 5873 N N . GLN B 1 376 ? -15.887 -27.154 -0.801 1.00 114.00 ? 372 GLN B N 1 ATOM 5874 C CA . GLN B 1 376 ? -15.009 -26.191 -1.463 1.00 109.68 ? 372 GLN B CA 1 ATOM 5875 C C . GLN B 1 376 ? -15.759 -25.172 -2.309 1.00 108.89 ? 372 GLN B C 1 ATOM 5876 O O . GLN B 1 376 ? -16.925 -25.363 -2.651 1.00 116.10 ? 372 GLN B O 1 ATOM 5877 C CB . GLN B 1 376 ? -14.004 -26.917 -2.354 1.00 114.69 ? 372 GLN B CB 1 ATOM 5878 C CG . GLN B 1 376 ? -12.903 -27.637 -1.613 1.00 108.61 ? 372 GLN B CG 1 ATOM 5879 C CD . GLN B 1 376 ? -11.745 -27.978 -2.523 1.00 108.75 ? 372 GLN B CD 1 ATOM 5880 O OE1 . GLN B 1 376 ? -10.582 -27.836 -2.149 1.00 110.24 ? 372 GLN B OE1 1 ATOM 5881 N NE2 . GLN B 1 376 ? -12.058 -28.426 -3.733 1.00 104.68 ? 372 GLN B NE2 1 ATOM 5882 N N . CYS B 1 377 ? -15.061 -24.090 -2.643 1.00 110.20 ? 373 CYS B N 1 ATOM 5883 C CA . CYS B 1 377 ? -15.551 -23.093 -3.585 1.00 116.02 ? 373 CYS B CA 1 ATOM 5884 C C . CYS B 1 377 ? -14.463 -22.795 -4.613 1.00 114.88 ? 373 CYS B C 1 ATOM 5885 O O . CYS B 1 377 ? -13.392 -22.292 -4.266 1.00 112.55 ? 373 CYS B O 1 ATOM 5886 C CB . CYS B 1 377 ? -15.967 -21.813 -2.856 1.00 120.29 ? 373 CYS B CB 1 ATOM 5887 S SG . CYS B 1 377 ? -16.296 -20.401 -3.939 1.00 120.70 ? 373 CYS B SG 1 ATOM 5888 N N . PHE B 1 378 ? -14.743 -23.113 -5.874 1.00 113.10 ? 374 PHE B N 1 ATOM 5889 C CA . PHE B 1 378 ? -13.786 -22.908 -6.957 1.00 106.53 ? 374 PHE B CA 1 ATOM 5890 C C . PHE B 1 378 ? -14.163 -21.695 -7.799 1.00 106.75 ? 374 PHE B C 1 ATOM 5891 O O . PHE B 1 378 ? -15.150 -21.722 -8.535 1.00 112.77 ? 374 PHE B O 1 ATOM 5892 C CB . PHE B 1 378 ? -13.708 -24.153 -7.847 1.00 114.17 ? 374 PHE B CB 1 ATOM 5893 C CG . PHE B 1 378 ? -12.377 -24.848 -7.806 1.00 115.94 ? 374 PHE B CG 1 ATOM 5894 C CD1 . PHE B 1 378 ? -11.305 -24.363 -8.537 1.00 116.76 ? 374 PHE B CD1 1 ATOM 5895 C CD2 . PHE B 1 378 ? -12.199 -25.990 -7.045 1.00 114.01 ? 374 PHE B CD2 1 ATOM 5896 C CE1 . PHE B 1 378 ? -10.082 -25.001 -8.503 1.00 101.93 ? 374 PHE B CE1 1 ATOM 5897 C CE2 . PHE B 1 378 ? -10.978 -26.632 -7.009 1.00 107.61 ? 374 PHE B CE2 1 ATOM 5898 C CZ . PHE B 1 378 ? -9.919 -26.137 -7.738 1.00 107.78 ? 374 PHE B CZ 1 ATOM 5899 N N . VAL B 1 379 ? -13.368 -20.635 -7.686 1.00 106.07 ? 375 VAL B N 1 ATOM 5900 C CA . VAL B 1 379 ? -13.536 -19.450 -8.519 1.00 101.25 ? 375 VAL B CA 1 ATOM 5901 C C . VAL B 1 379 ? -12.621 -19.582 -9.729 1.00 88.47 ? 375 VAL B C 1 ATOM 5902 O O . VAL B 1 379 ? -11.397 -19.621 -9.595 1.00 99.37 ? 375 VAL B O 1 ATOM 5903 C CB . VAL B 1 379 ? -13.227 -18.154 -7.743 1.00 95.13 ? 375 VAL B CB 1 ATOM 5904 C CG1 . VAL B 1 379 ? -13.213 -16.945 -8.680 1.00 84.82 ? 375 VAL B CG1 1 ATOM 5905 C CG2 . VAL B 1 379 ? -14.250 -17.961 -6.633 1.00 99.31 ? 375 VAL B CG2 1 ATOM 5906 N N . ARG B 1 380 ? -13.231 -19.648 -10.908 1.00 91.16 ? 376 ARG B N 1 ATOM 5907 C CA . ARG B 1 380 ? -12.522 -19.992 -12.133 1.00 94.19 ? 376 ARG B CA 1 ATOM 5908 C C . ARG B 1 380 ? -12.753 -18.961 -13.232 1.00 87.25 ? 376 ARG B C 1 ATOM 5909 O O . ARG B 1 380 ? -13.742 -18.227 -13.218 1.00 82.87 ? 376 ARG B O 1 ATOM 5910 C CB . ARG B 1 380 ? -12.972 -21.374 -12.622 1.00 101.93 ? 376 ARG B CB 1 ATOM 5911 C CG . ARG B 1 380 ? -11.979 -22.092 -13.527 1.00 94.10 ? 376 ARG B CG 1 ATOM 5912 C CD . ARG B 1 380 ? -10.895 -22.810 -12.734 1.00 85.48 ? 376 ARG B CD 1 ATOM 5913 N NE . ARG B 1 380 ? -10.362 -23.967 -13.455 1.00 88.92 ? 376 ARG B NE 1 ATOM 5914 C CZ . ARG B 1 380 ? -10.663 -25.238 -13.191 1.00 90.20 ? 376 ARG B CZ 1 ATOM 5915 N NH1 . ARG B 1 380 ? -11.497 -25.558 -12.209 1.00 92.14 ? 376 ARG B NH1 1 ATOM 5916 N NH2 . ARG B 1 380 ? -10.116 -26.204 -13.915 1.00 94.82 ? 376 ARG B NH2 1 ATOM 5917 N N . ASN B 1 381 ? -11.818 -18.908 -14.175 1.00 92.58 ? 377 ASN B N 1 ATOM 5918 C CA . ASN B 1 381 ? -12.025 -18.233 -15.450 1.00 98.53 ? 377 ASN B CA 1 ATOM 5919 C C . ASN B 1 381 ? -11.133 -18.913 -16.484 1.00 95.57 ? 377 ASN B C 1 ATOM 5920 O O . ASN B 1 381 ? -10.573 -19.973 -16.202 1.00 88.31 ? 377 ASN B O 1 ATOM 5921 C CB . ASN B 1 381 ? -11.747 -16.730 -15.352 1.00 95.80 ? 377 ASN B CB 1 ATOM 5922 C CG . ASN B 1 381 ? -10.289 -16.412 -15.125 1.00 91.44 ? 377 ASN B CG 1 ATOM 5923 O OD1 . ASN B 1 381 ? -9.827 -16.368 -13.986 1.00 95.81 ? 377 ASN B OD1 1 ATOM 5924 N ND2 . ASN B 1 381 ? -9.559 -16.159 -16.206 1.00 92.47 ? 377 ASN B ND2 1 ATOM 5925 N N . ASP B 1 382 ? -11.009 -18.319 -17.670 1.00 99.89 ? 378 ASP B N 1 ATOM 5926 C CA . ASP B 1 382 ? -10.428 -19.014 -18.823 1.00 106.17 ? 378 ASP B CA 1 ATOM 5927 C C . ASP B 1 382 ? -9.079 -19.665 -18.504 1.00 102.70 ? 378 ASP B C 1 ATOM 5928 O O . ASP B 1 382 ? -9.003 -20.892 -18.400 1.00 99.40 ? 378 ASP B O 1 ATOM 5929 C CB . ASP B 1 382 ? -10.275 -18.046 -19.998 1.00 112.88 ? 378 ASP B CB 1 ATOM 5930 C CG . ASP B 1 382 ? -11.552 -17.285 -20.295 1.00 105.43 ? 378 ASP B CG 1 ATOM 5931 O OD1 . ASP B 1 382 ? -12.134 -16.707 -19.352 1.00 109.12 ? 378 ASP B OD1 1 ATOM 5932 O OD2 . ASP B 1 382 ? -11.980 -17.272 -21.468 1.00 100.14 ? 378 ASP B OD2 1 ATOM 5933 N N . GLN B 1 383 ? -8.023 -18.866 -18.357 1.00 101.28 ? 379 GLN B N 1 ATOM 5934 C CA . GLN B 1 383 ? -6.806 -19.356 -17.718 1.00 110.65 ? 379 GLN B CA 1 ATOM 5935 C C . GLN B 1 383 ? -6.527 -18.559 -16.453 1.00 106.35 ? 379 GLN B C 1 ATOM 5936 O O . GLN B 1 383 ? -5.997 -17.449 -16.505 1.00 98.65 ? 379 GLN B O 1 ATOM 5937 C CB . GLN B 1 383 ? -5.622 -19.267 -18.679 1.00 115.40 ? 379 GLN B CB 1 ATOM 5938 C CG . GLN B 1 383 ? -5.712 -20.238 -19.843 1.00 114.07 ? 379 GLN B CG 1 ATOM 5939 C CD . GLN B 1 383 ? -4.586 -20.063 -20.841 1.00 113.57 ? 379 GLN B CD 1 ATOM 5940 O OE1 . GLN B 1 383 ? -3.897 -19.043 -20.846 1.00 100.79 ? 379 GLN B OE1 1 ATOM 5941 N NE2 . GLN B 1 383 ? -4.390 -21.062 -21.692 1.00 116.78 ? 379 GLN B NE2 1 ATOM 5942 N N . GLU B 1 384 ? -6.878 -19.163 -15.322 1.00 105.19 ? 380 GLU B N 1 ATOM 5943 C CA . GLU B 1 384 ? -6.605 -18.642 -13.988 1.00 95.09 ? 380 GLU B CA 1 ATOM 5944 C C . GLU B 1 384 ? -7.410 -19.519 -13.041 1.00 97.67 ? 380 GLU B C 1 ATOM 5945 O O . GLU B 1 384 ? -8.243 -20.303 -13.498 1.00 99.87 ? 380 GLU B O 1 ATOM 5946 C CB . GLU B 1 384 ? -6.987 -17.166 -13.850 1.00 95.09 ? 380 GLU B CB 1 ATOM 5947 C CG . GLU B 1 384 ? -5.797 -16.216 -13.777 1.00 105.92 ? 380 GLU B CG 1 ATOM 5948 C CD . GLU B 1 384 ? -5.285 -16.019 -12.363 1.00 107.10 ? 380 GLU B CD 1 ATOM 5949 O OE1 . GLU B 1 384 ? -5.534 -16.893 -11.506 1.00 99.55 ? 380 GLU B OE1 1 ATOM 5950 O OE2 . GLU B 1 384 ? -4.635 -14.983 -12.107 1.00 112.02 ? 380 GLU B OE2 1 ATOM 5951 N N . SER B 1 385 ? -7.203 -19.370 -11.737 1.00 97.97 ? 381 SER B N 1 ATOM 5952 C CA . SER B 1 385 ? -8.014 -20.090 -10.758 1.00 91.01 ? 381 SER B CA 1 ATOM 5953 C C . SER B 1 385 ? -7.666 -19.702 -9.331 1.00 98.68 ? 381 SER B C 1 ATOM 5954 O O . SER B 1 385 ? -6.627 -19.097 -9.068 1.00 110.24 ? 381 SER B O 1 ATOM 5955 C CB . SER B 1 385 ? -7.846 -21.607 -10.909 1.00 94.61 ? 381 SER B CB 1 ATOM 5956 O OG . SER B 1 385 ? -8.715 -22.295 -10.027 1.00 99.36 ? 381 SER B OG 1 ATOM 5957 N N . ALA B 1 386 ? -8.562 -20.054 -8.417 1.00 98.82 ? 382 ALA B N 1 ATOM 5958 C CA . ALA B 1 386 ? -8.316 -19.909 -6.991 1.00 109.04 ? 382 ALA B CA 1 ATOM 5959 C C . ALA B 1 386 ? -9.207 -20.888 -6.242 1.00 112.01 ? 382 ALA B C 1 ATOM 5960 O O . ALA B 1 386 ? -10.234 -21.326 -6.764 1.00 105.50 ? 382 ALA B O 1 ATOM 5961 C CB . ALA B 1 386 ? -8.573 -18.483 -6.538 1.00 102.50 ? 382 ALA B CB 1 ATOM 5962 N N . GLU B 1 387 ? -8.817 -21.228 -5.019 1.00 122.23 ? 383 GLU B N 1 ATOM 5963 C CA . GLU B 1 387 ? -9.563 -22.198 -4.230 1.00 117.57 ? 383 GLU B CA 1 ATOM 5964 C C . GLU B 1 387 ? -9.477 -21.901 -2.742 1.00 126.94 ? 383 GLU B C 1 ATOM 5965 O O . GLU B 1 387 ? -8.446 -21.459 -2.232 1.00 150.60 ? 383 GLU B O 1 ATOM 5966 C CB . GLU B 1 387 ? -9.057 -23.618 -4.514 1.00 115.66 ? 383 GLU B CB 1 ATOM 5967 C CG . GLU B 1 387 ? -9.478 -24.668 -3.482 1.00 111.70 ? 383 GLU B CG 1 ATOM 5968 C CD . GLU B 1 387 ? -8.580 -24.701 -2.256 1.00 120.26 ? 383 GLU B CD 1 ATOM 5969 O OE1 . GLU B 1 387 ? -7.656 -23.863 -2.162 1.00 130.89 ? 383 GLU B OE1 1 ATOM 5970 O OE2 . GLU B 1 387 ? -8.805 -25.562 -1.380 1.00 116.56 ? 383 GLU B OE2 1 ATOM 5971 N N . ALA B 1 388 ? -10.584 -22.160 -2.058 1.00 117.51 ? 384 ALA B N 1 ATOM 5972 C CA . ALA B 1 388 ? -10.644 -22.110 -0.609 1.00 117.65 ? 384 ALA B CA 1 ATOM 5973 C C . ALA B 1 388 ? -11.718 -23.090 -0.163 1.00 107.51 ? 384 ALA B C 1 ATOM 5974 O O . ALA B 1 388 ? -12.540 -23.519 -0.974 1.00 104.32 ? 384 ALA B O 1 ATOM 5975 C CB . ALA B 1 388 ? -10.941 -20.706 -0.124 1.00 118.20 ? 384 ALA B CB 1 ATOM 5976 N N . SER B 1 389 ? -11.710 -23.451 1.116 1.00 105.05 ? 385 SER B N 1 ATOM 5977 C CA . SER B 1 389 ? -12.598 -24.497 1.605 1.00 117.28 ? 385 SER B CA 1 ATOM 5978 C C . SER B 1 389 ? -13.199 -24.194 2.968 1.00 112.72 ? 385 SER B C 1 ATOM 5979 O O . SER B 1 389 ? -12.746 -23.304 3.691 1.00 106.13 ? 385 SER B O 1 ATOM 5980 C CB . SER B 1 389 ? -11.843 -25.826 1.670 1.00 124.53 ? 385 SER B CB 1 ATOM 5981 O OG . SER B 1 389 ? -10.709 -25.726 2.512 1.00 121.08 ? 385 SER B OG 1 ATOM 5982 N N . ALA B 1 390 ? -14.235 -24.956 3.297 1.00 103.87 ? 386 ALA B N 1 ATOM 5983 C CA . ALA B 1 390 ? -14.856 -24.926 4.609 1.00 106.91 ? 386 ALA B CA 1 ATOM 5984 C C . ALA B 1 390 ? -15.477 -26.292 4.856 1.00 113.67 ? 386 ALA B C 1 ATOM 5985 O O . ALA B 1 390 ? -15.661 -27.070 3.920 1.00 123.17 ? 386 ALA B O 1 ATOM 5986 C CB . ALA B 1 390 ? -15.901 -23.826 4.701 1.00 118.87 ? 386 ALA B CB 1 ATOM 5987 N N . GLU B 1 391 ? -15.790 -26.588 6.112 1.00 116.95 ? 387 GLU B N 1 ATOM 5988 C CA . GLU B 1 391 ? -16.314 -27.898 6.468 1.00 120.14 ? 387 GLU B CA 1 ATOM 5989 C C . GLU B 1 391 ? -17.373 -27.810 7.553 1.00 118.74 ? 387 GLU B C 1 ATOM 5990 O O . GLU B 1 391 ? -17.304 -26.961 8.442 1.00 129.04 ? 387 GLU B O 1 ATOM 5991 C CB . GLU B 1 391 ? -15.180 -28.816 6.921 1.00 118.62 ? 387 GLU B CB 1 ATOM 5992 C CG . GLU B 1 391 ? -13.963 -28.076 7.467 1.00 127.46 ? 387 GLU B CG 1 ATOM 5993 C CD . GLU B 1 391 ? -12.900 -29.008 8.019 1.00 129.96 ? 387 GLU B CD 1 ATOM 5994 O OE1 . GLU B 1 391 ? -13.221 -30.179 8.309 1.00 125.23 ? 387 GLU B OE1 1 ATOM 5995 O OE2 . GLU B 1 391 ? -11.738 -28.570 8.158 1.00 136.31 ? 387 GLU B OE2 1 ATOM 5996 N N . LEU B 1 392 ? -18.353 -28.703 7.463 1.00 106.10 ? 388 LEU B N 1 ATOM 5997 C CA . LEU B 1 392 ? -19.439 -28.764 8.427 1.00 111.22 ? 388 LEU B CA 1 ATOM 5998 C C . LEU B 1 392 ? -19.390 -30.070 9.207 1.00 119.91 ? 388 LEU B C 1 ATOM 5999 O O . LEU B 1 392 ? -19.418 -31.154 8.622 1.00 128.84 ? 388 LEU B O 1 ATOM 6000 C CB . LEU B 1 392 ? -20.789 -28.620 7.724 1.00 123.51 ? 388 LEU B CB 1 ATOM 6001 C CG . LEU B 1 392 ? -22.008 -28.825 8.624 1.00 125.63 ? 388 LEU B CG 1 ATOM 6002 C CD1 . LEU B 1 392 ? -21.978 -27.861 9.798 1.00 124.08 ? 388 LEU B CD1 1 ATOM 6003 C CD2 . LEU B 1 392 ? -23.291 -28.663 7.829 1.00 133.63 ? 388 LEU B CD2 1 ATOM 6004 N N . LYS B 1 393 ? -19.315 -29.956 10.529 1.00 120.39 ? 389 LYS B N 1 ATOM 6005 C CA . LYS B 1 393 ? -19.328 -31.118 11.410 1.00 128.32 ? 389 LYS B CA 1 ATOM 6006 C C . LYS B 1 393 ? -20.732 -31.341 11.965 1.00 130.85 ? 389 LYS B C 1 ATOM 6007 O O . LYS B 1 393 ? -21.468 -30.387 12.217 1.00 130.07 ? 389 LYS B O 1 ATOM 6008 C CB . LYS B 1 393 ? -18.322 -30.944 12.549 1.00 132.47 ? 389 LYS B CB 1 ATOM 6009 C CG . LYS B 1 393 ? -18.397 -32.027 13.609 1.00 135.41 ? 389 LYS B CG 1 ATOM 6010 C CD . LYS B 1 393 ? -17.185 -31.991 14.518 1.00 136.10 ? 389 LYS B CD 1 ATOM 6011 C CE . LYS B 1 393 ? -17.502 -32.583 15.880 1.00 125.78 ? 389 LYS B CE 1 ATOM 6012 N NZ . LYS B 1 393 ? -18.003 -33.983 15.789 1.00 138.87 ? 389 LYS B NZ 1 ATOM 6013 N N . LEU B 1 394 ? -21.098 -32.607 12.134 1.00 127.96 ? 390 LEU B N 1 ATOM 6014 C CA . LEU B 1 394 ? -22.423 -32.975 12.618 1.00 127.03 ? 390 LEU B CA 1 ATOM 6015 C C . LEU B 1 394 ? -22.408 -33.239 14.121 1.00 128.84 ? 390 LEU B C 1 ATOM 6016 O O . LEU B 1 394 ? -21.747 -34.166 14.590 1.00 126.89 ? 390 LEU B O 1 ATOM 6017 C CB . LEU B 1 394 ? -22.931 -34.209 11.868 1.00 132.37 ? 390 LEU B CB 1 ATOM 6018 C CG . LEU B 1 394 ? -23.527 -33.965 10.478 1.00 133.91 ? 390 LEU B CG 1 ATOM 6019 C CD1 . LEU B 1 394 ? -22.703 -32.974 9.662 1.00 126.94 ? 390 LEU B CD1 1 ATOM 6020 C CD2 . LEU B 1 394 ? -23.654 -35.282 9.730 1.00 134.64 ? 390 LEU B CD2 1 ATOM 6021 N N . GLY B 1 395 ? -23.137 -32.414 14.866 1.00 128.60 ? 391 GLY B N 1 ATOM 6022 C CA . GLY B 1 395 ? -23.228 -32.551 16.310 1.00 130.96 ? 391 GLY B CA 1 ATOM 6023 C C . GLY B 1 395 ? -24.629 -32.269 16.818 1.00 133.79 ? 391 GLY B C 1 ATOM 6024 O O . GLY B 1 395 ? -24.909 -31.183 17.325 1.00 136.60 ? 391 GLY B O 1 HETATM 6025 C C1 . NAG C 2 . ? 3.045 14.299 -61.329 1.00 36.03 ? 401 NAG A C1 1 HETATM 6026 C C2 . NAG C 2 . ? 3.766 14.786 -62.564 1.00 48.09 ? 401 NAG A C2 1 HETATM 6027 C C3 . NAG C 2 . ? 4.919 13.848 -62.875 1.00 49.78 ? 401 NAG A C3 1 HETATM 6028 C C4 . NAG C 2 . ? 5.840 13.731 -61.662 1.00 47.77 ? 401 NAG A C4 1 HETATM 6029 C C5 . NAG C 2 . ? 5.076 13.469 -60.357 1.00 45.93 ? 401 NAG A C5 1 HETATM 6030 C C6 . NAG C 2 . ? 5.944 13.698 -59.139 1.00 52.15 ? 401 NAG A C6 1 HETATM 6031 C C7 . NAG C 2 . ? 2.634 16.057 -64.339 1.00 38.68 ? 401 NAG A C7 1 HETATM 6032 C C8 . NAG C 2 . ? 1.677 16.002 -65.493 1.00 39.32 ? 401 NAG A C8 1 HETATM 6033 N N2 . NAG C 2 . ? 2.863 14.898 -63.705 1.00 28.15 ? 401 NAG A N2 1 HETATM 6034 O O3 . NAG C 2 . ? 5.643 14.344 -63.995 1.00 47.91 ? 401 NAG A O3 1 HETATM 6035 O O4 . NAG C 2 . ? 6.723 12.635 -61.863 1.00 67.89 ? 401 NAG A O4 1 HETATM 6036 O O5 . NAG C 2 . ? 3.937 14.338 -60.221 1.00 49.43 ? 401 NAG A O5 1 HETATM 6037 O O6 . NAG C 2 . ? 5.233 13.515 -57.923 1.00 50.16 ? 401 NAG A O6 1 HETATM 6038 O O7 . NAG C 2 . ? 3.169 17.106 -63.994 1.00 59.35 ? 401 NAG A O7 1 HETATM 6039 C C1 . NAG D 2 . ? 8.057 12.963 -61.462 1.00 65.32 ? 402 NAG A C1 1 HETATM 6040 C C2 . NAG D 2 . ? 8.828 11.637 -61.386 1.00 57.62 ? 402 NAG A C2 1 HETATM 6041 C C3 . NAG D 2 . ? 10.318 11.894 -61.167 1.00 72.53 ? 402 NAG A C3 1 HETATM 6042 C C4 . NAG D 2 . ? 10.847 12.854 -62.222 1.00 76.85 ? 402 NAG A C4 1 HETATM 6043 C C5 . NAG D 2 . ? 10.030 14.138 -62.179 1.00 71.02 ? 402 NAG A C5 1 HETATM 6044 C C6 . NAG D 2 . ? 10.445 15.151 -63.220 1.00 65.67 ? 402 NAG A C6 1 HETATM 6045 C C7 . NAG D 2 . ? 7.431 9.789 -60.494 1.00 52.39 ? 402 NAG A C7 1 HETATM 6046 C C8 . NAG D 2 . ? 6.994 9.514 -61.902 1.00 42.20 ? 402 NAG A C8 1 HETATM 6047 N N2 . NAG D 2 . ? 8.298 10.798 -60.318 1.00 43.87 ? 402 NAG A N2 1 HETATM 6048 O O3 . NAG D 2 . ? 11.023 10.660 -61.238 1.00 78.52 ? 402 NAG A O3 1 HETATM 6049 O O4 . NAG D 2 . ? 12.229 13.124 -62.011 1.00 76.99 ? 402 NAG A O4 1 HETATM 6050 O O5 . NAG D 2 . ? 8.658 13.819 -62.441 1.00 69.72 ? 402 NAG A O5 1 HETATM 6051 O O6 . NAG D 2 . ? 9.316 15.721 -63.869 1.00 46.63 ? 402 NAG A O6 1 HETATM 6052 O O7 . NAG D 2 . ? 7.022 9.120 -59.549 1.00 58.69 ? 402 NAG A O7 1 HETATM 6053 C C1 . BMA E 3 . ? 12.905 12.807 -63.243 1.00 79.16 ? 403 BMA A C1 1 HETATM 6054 C C2 . BMA E 3 . ? 14.076 13.769 -63.472 1.00 82.42 ? 403 BMA A C2 1 HETATM 6055 C C3 . BMA E 3 . ? 14.730 13.450 -64.817 1.00 77.43 ? 403 BMA A C3 1 HETATM 6056 C C4 . BMA E 3 . ? 15.062 11.947 -64.938 1.00 71.87 ? 403 BMA A C4 1 HETATM 6057 C C5 . BMA E 3 . ? 13.816 11.090 -64.662 1.00 83.86 ? 403 BMA A C5 1 HETATM 6058 C C6 . BMA E 3 . ? 14.124 9.592 -64.676 1.00 94.93 ? 403 BMA A C6 1 HETATM 6059 O O2 . BMA E 3 . ? 15.094 13.602 -62.483 1.00 78.41 ? 403 BMA A O2 1 HETATM 6060 O O3 . BMA E 3 . ? 15.901 14.228 -65.036 1.00 71.12 ? 403 BMA A O3 1 HETATM 6061 O O4 . BMA E 3 . ? 15.547 11.660 -66.242 1.00 63.05 ? 403 BMA A O4 1 HETATM 6062 O O5 . BMA E 3 . ? 13.279 11.449 -63.364 1.00 87.13 ? 403 BMA A O5 1 HETATM 6063 O O6 . BMA E 3 . ? 12.886 8.850 -64.585 1.00 87.79 ? 403 BMA A O6 1 HETATM 6064 C C1 . MAN F 4 . ? 12.404 8.416 -63.286 1.00 87.76 ? 404 MAN A C1 1 HETATM 6065 C C2 . MAN F 4 . ? 13.395 8.478 -62.098 1.00 96.41 ? 404 MAN A C2 1 HETATM 6066 C C3 . MAN F 4 . ? 12.744 7.957 -60.807 1.00 90.62 ? 404 MAN A C3 1 HETATM 6067 C C4 . MAN F 4 . ? 11.859 6.682 -60.994 1.00 97.09 ? 404 MAN A C4 1 HETATM 6068 C C5 . MAN F 4 . ? 11.038 6.676 -62.320 1.00 85.97 ? 404 MAN A C5 1 HETATM 6069 C C6 . MAN F 4 . ? 9.756 7.511 -62.258 1.00 76.09 ? 404 MAN A C6 1 HETATM 6070 O O2 . MAN F 4 . ? 13.772 9.826 -61.783 1.00 104.03 ? 404 MAN A O2 1 HETATM 6071 O O3 . MAN F 4 . ? 11.991 8.982 -60.159 1.00 89.95 ? 404 MAN A O3 1 HETATM 6072 O O4 . MAN F 4 . ? 12.680 5.521 -60.938 1.00 113.30 ? 404 MAN A O4 1 HETATM 6073 O O5 . MAN F 4 . ? 11.834 7.148 -63.422 1.00 86.04 ? 404 MAN A O5 1 HETATM 6074 O O6 . MAN F 4 . ? 8.652 6.653 -62.532 1.00 74.99 ? 404 MAN A O6 1 HETATM 6075 C C1 . NAG G 2 . ? -12.289 -25.688 -27.226 1.00 92.90 ? 405 NAG A C1 1 HETATM 6076 C C2 . NAG G 2 . ? -13.267 -26.521 -26.417 1.00 106.39 ? 405 NAG A C2 1 HETATM 6077 C C3 . NAG G 2 . ? -14.411 -25.640 -25.920 1.00 109.41 ? 405 NAG A C3 1 HETATM 6078 C C4 . NAG G 2 . ? -13.887 -24.401 -25.202 1.00 106.97 ? 405 NAG A C4 1 HETATM 6079 C C5 . NAG G 2 . ? -12.787 -23.705 -26.013 1.00 91.41 ? 405 NAG A C5 1 HETATM 6080 C C6 . NAG G 2 . ? -12.074 -22.626 -25.230 1.00 91.79 ? 405 NAG A C6 1 HETATM 6081 C C7 . NAG G 2 . ? -13.141 -28.812 -27.291 1.00 94.56 ? 405 NAG A C7 1 HETATM 6082 C C8 . NAG G 2 . ? -13.812 -29.853 -28.134 1.00 93.25 ? 405 NAG A C8 1 HETATM 6083 N N2 . NAG G 2 . ? -13.774 -27.636 -27.190 1.00 100.90 ? 405 NAG A N2 1 HETATM 6084 O O3 . NAG G 2 . ? -15.231 -26.399 -25.038 1.00 112.23 ? 405 NAG A O3 1 HETATM 6085 O O4 . NAG G 2 . ? -14.961 -23.478 -25.048 1.00 110.19 ? 405 NAG A O4 1 HETATM 6086 O O5 . NAG G 2 . ? -11.778 -24.641 -26.428 1.00 87.94 ? 405 NAG A O5 1 HETATM 6087 O O6 . NAG G 2 . ? -10.935 -22.146 -25.931 1.00 75.77 ? 405 NAG A O6 1 HETATM 6088 O O7 . NAG G 2 . ? -12.071 -29.021 -26.726 1.00 96.02 ? 405 NAG A O7 1 HETATM 6089 C C1 . NAG H 2 . ? -15.403 -23.209 -23.692 1.00 115.83 ? 406 NAG A C1 1 HETATM 6090 C C2 . NAG H 2 . ? -16.314 -24.302 -23.127 1.00 121.52 ? 406 NAG A C2 1 HETATM 6091 C C3 . NAG H 2 . ? -16.911 -23.850 -21.793 1.00 119.00 ? 406 NAG A C3 1 HETATM 6092 C C4 . NAG H 2 . ? -15.817 -23.370 -20.847 1.00 109.06 ? 406 NAG A C4 1 HETATM 6093 C C5 . NAG H 2 . ? -14.921 -22.342 -21.534 1.00 119.44 ? 406 NAG A C5 1 HETATM 6094 C C6 . NAG H 2 . ? -13.746 -21.917 -20.684 1.00 132.63 ? 406 NAG A C6 1 HETATM 6095 C C7 . NAG H 2 . ? -18.225 -25.648 -23.897 1.00 125.43 ? 406 NAG A C7 1 HETATM 6096 C C8 . NAG H 2 . ? -19.248 -25.839 -24.977 1.00 121.94 ? 406 NAG A C8 1 HETATM 6097 N N2 . NAG H 2 . ? -17.368 -24.635 -24.074 1.00 128.16 ? 406 NAG A N2 1 HETATM 6098 O O3 . NAG H 2 . ? -17.616 -24.930 -21.190 1.00 124.77 ? 406 NAG A O3 1 HETATM 6099 O O4 . NAG H 2 . ? -16.407 -22.780 -19.694 1.00 102.08 ? 406 NAG A O4 1 HETATM 6100 O O5 . NAG H 2 . ? -14.383 -22.898 -22.743 1.00 118.33 ? 406 NAG A O5 1 HETATM 6101 O O6 . NAG H 2 . ? -12.557 -22.600 -21.055 1.00 131.22 ? 406 NAG A O6 1 HETATM 6102 O O7 . NAG H 2 . ? -18.180 -26.374 -22.909 1.00 137.33 ? 406 NAG A O7 1 HETATM 6103 ZN ZN . ZN I 5 . ? -20.327 11.913 -49.325 1.00 92.29 ? 407 ZN A ZN 1 HETATM 6104 ZN ZN . ZN J 5 . ? -29.249 10.607 -58.106 1.00 74.10 ? 408 ZN A ZN 1 HETATM 6105 ZN ZN . ZN K 5 . ? 6.636 -5.529 -42.758 1.00 206.39 ? 409 ZN A ZN 1 HETATM 6106 ZN ZN . ZN L 5 . ? 7.864 -9.775 -40.503 1.00 176.20 ? 410 ZN A ZN 1 HETATM 6107 C C1 . NAG M 2 . ? 17.691 -29.206 -24.778 1.00 87.83 ? 401 NAG B C1 1 HETATM 6108 C C2 . NAG M 2 . ? 19.028 -29.883 -24.503 1.00 96.72 ? 401 NAG B C2 1 HETATM 6109 C C3 . NAG M 2 . ? 20.114 -29.259 -25.373 1.00 104.04 ? 401 NAG B C3 1 HETATM 6110 C C4 . NAG M 2 . ? 19.711 -29.313 -26.842 1.00 106.82 ? 401 NAG B C4 1 HETATM 6111 C C5 . NAG M 2 . ? 18.323 -28.707 -27.048 1.00 100.02 ? 401 NAG B C5 1 HETATM 6112 C C6 . NAG M 2 . ? 17.801 -28.906 -28.454 1.00 106.33 ? 401 NAG B C6 1 HETATM 6113 C C7 . NAG M 2 . ? 19.898 -30.833 -22.409 1.00 86.82 ? 401 NAG B C7 1 HETATM 6114 C C8 . NAG M 2 . ? 20.208 -30.577 -20.965 1.00 83.05 ? 401 NAG B C8 1 HETATM 6115 N N2 . NAG M 2 . ? 19.386 -29.803 -23.095 1.00 89.97 ? 401 NAG B N2 1 HETATM 6116 O O3 . NAG M 2 . ? 21.338 -29.957 -25.179 1.00 111.62 ? 401 NAG B O3 1 HETATM 6117 O O4 . NAG M 2 . ? 20.656 -28.596 -27.629 1.00 108.84 ? 401 NAG B O4 1 HETATM 6118 O O5 . NAG M 2 . ? 17.370 -29.326 -26.168 1.00 83.54 ? 401 NAG B O5 1 HETATM 6119 O O6 . NAG M 2 . ? 18.831 -28.767 -29.422 1.00 112.61 ? 401 NAG B O6 1 HETATM 6120 O O7 . NAG M 2 . ? 20.094 -31.926 -22.928 1.00 95.30 ? 401 NAG B O7 1 HETATM 6121 C C1 . NAG N 2 . ? -13.128 13.945 -36.203 1.00 90.72 ? 402 NAG B C1 1 HETATM 6122 C C2 . NAG N 2 . ? -13.923 15.195 -36.599 1.00 78.95 ? 402 NAG B C2 1 HETATM 6123 C C3 . NAG N 2 . ? -15.383 14.836 -36.874 1.00 85.28 ? 402 NAG B C3 1 HETATM 6124 C C4 . NAG N 2 . ? -15.444 13.731 -37.919 1.00 90.45 ? 402 NAG B C4 1 HETATM 6125 C C5 . NAG N 2 . ? -14.659 12.528 -37.412 1.00 86.93 ? 402 NAG B C5 1 HETATM 6126 C C6 . NAG N 2 . ? -14.641 11.369 -38.382 1.00 81.51 ? 402 NAG B C6 1 HETATM 6127 C C7 . NAG N 2 . ? -13.531 17.499 -35.773 1.00 98.16 ? 402 NAG B C7 1 HETATM 6128 C C8 . NAG N 2 . ? -13.287 17.904 -37.197 1.00 94.56 ? 402 NAG B C8 1 HETATM 6129 N N2 . NAG N 2 . ? -13.831 16.210 -35.557 1.00 82.94 ? 402 NAG B N2 1 HETATM 6130 O O3 . NAG N 2 . ? -16.070 15.992 -37.339 1.00 91.74 ? 402 NAG B O3 1 HETATM 6131 O O4 . NAG N 2 . ? -16.780 13.384 -38.280 1.00 98.26 ? 402 NAG B O4 1 HETATM 6132 O O5 . NAG N 2 . ? -13.296 12.921 -37.206 1.00 91.00 ? 402 NAG B O5 1 HETATM 6133 O O6 . NAG N 2 . ? -14.930 11.787 -39.710 1.00 81.73 ? 402 NAG B O6 1 HETATM 6134 O O7 . NAG N 2 . ? -13.464 18.309 -34.852 1.00 103.45 ? 402 NAG B O7 1 HETATM 6135 C C1 . NAG O 2 . ? -17.658 12.864 -37.259 1.00 94.28 ? 403 NAG B C1 1 HETATM 6136 C C2 . NAG O 2 . ? -19.042 12.773 -37.912 1.00 102.56 ? 403 NAG B C2 1 HETATM 6137 C C3 . NAG O 2 . ? -20.050 12.153 -36.947 1.00 105.76 ? 403 NAG B C3 1 HETATM 6138 C C4 . NAG O 2 . ? -19.532 10.820 -36.423 1.00 100.77 ? 403 NAG B C4 1 HETATM 6139 C C5 . NAG O 2 . ? -18.155 11.017 -35.800 1.00 100.50 ? 403 NAG B C5 1 HETATM 6140 C C6 . NAG O 2 . ? -17.529 9.729 -35.315 1.00 96.19 ? 403 NAG B C6 1 HETATM 6141 C C7 . NAG O 2 . ? -19.172 14.613 -39.540 1.00 112.98 ? 403 NAG B C7 1 HETATM 6142 C C8 . NAG O 2 . ? -19.737 15.972 -39.831 1.00 114.29 ? 403 NAG B C8 1 HETATM 6143 N N2 . NAG O 2 . ? -19.500 14.083 -38.356 1.00 106.71 ? 403 NAG B N2 1 HETATM 6144 O O3 . NAG O 2 . ? -21.290 11.962 -37.619 1.00 97.08 ? 403 NAG B O3 1 HETATM 6145 O O4 . NAG O 2 . ? -20.427 10.293 -35.450 1.00 88.30 ? 403 NAG B O4 1 HETATM 6146 O O5 . NAG O 2 . ? -17.267 11.568 -36.781 1.00 96.65 ? 403 NAG B O5 1 HETATM 6147 O O6 . NAG O 2 . ? -16.603 9.966 -34.264 1.00 82.47 ? 403 NAG B O6 1 HETATM 6148 O O7 . NAG O 2 . ? -18.447 14.027 -40.338 1.00 115.19 ? 403 NAG B O7 1 HETATM 6149 ZN ZN . ZN P 5 . ? -6.823 -23.614 -15.423 1.00 107.44 ? 404 ZN B ZN 1 HETATM 6150 ZN ZN . ZN Q 5 . ? -6.581 -22.179 -2.160 1.00 140.07 ? 405 ZN B ZN 1 HETATM 6151 O O . HOH R 6 . ? -29.216 8.542 -61.097 1.00 55.22 ? 501 HOH A O 1 HETATM 6152 O O . HOH R 6 . ? 9.792 19.244 -58.802 1.00 47.05 ? 502 HOH A O 1 HETATM 6153 O O . HOH R 6 . ? 3.474 -11.134 -40.619 1.00 153.47 ? 503 HOH A O 1 HETATM 6154 O O . HOH R 6 . ? 1.099 -15.550 -41.279 1.00 71.13 ? 504 HOH A O 1 HETATM 6155 O O . HOH R 6 . ? -19.750 12.145 -47.336 1.00 120.54 ? 505 HOH A O 1 HETATM 6156 O O . HOH R 6 . ? -11.987 14.810 -49.988 1.00 42.34 ? 506 HOH A O 1 HETATM 6157 O O . HOH S 6 . ? -4.276 13.289 -52.040 1.00 47.82 ? 501 HOH B O 1 HETATM 6158 O O . HOH S 6 . ? 3.255 -1.124 -36.963 1.00 103.08 ? 502 HOH B O 1 HETATM 6159 O O . HOH S 6 . ? 4.392 -3.281 -40.201 1.00 152.09 ? 503 HOH B O 1 HETATM 6160 O O . HOH S 6 . ? -4.324 -20.006 -0.689 1.00 138.98 ? 504 HOH B O 1 HETATM 6161 O O . HOH S 6 . ? -7.879 -23.723 -17.223 1.00 94.77 ? 505 HOH B O 1 HETATM 6162 O O . HOH S 6 . ? 1.794 12.840 -49.848 1.00 53.15 ? 506 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLY 1 -3 ? ? ? A . n A 1 2 GLY 2 -2 ? ? ? A . n A 1 3 ALA 3 -1 ? ? ? A . n A 1 4 ASP 4 0 ? ? ? A . n A 1 5 GLN 5 1 1 GLN GLN A . n A 1 6 LYS 6 2 2 LYS LYS A . n A 1 7 GLY 7 3 3 GLY GLY A . n A 1 8 PRO 8 4 4 PRO PRO A . n A 1 9 VAL 9 5 5 VAL VAL A . n A 1 10 PHE 10 6 6 PHE PHE A . n A 1 11 LEU 11 7 7 LEU LEU A . n A 1 12 LYS 12 8 8 LYS LYS A . n A 1 13 GLU 13 9 9 GLU GLU A . n A 1 14 PRO 14 10 10 PRO PRO A . n A 1 15 THR 15 11 11 THR THR A . n A 1 16 ASN 16 12 12 ASN ASN A . n A 1 17 ARG 17 13 13 ARG ARG A . n A 1 18 ILE 18 14 14 ILE ILE A . n A 1 19 ASP 19 15 15 ASP ASP A . n A 1 20 PHE 20 16 16 PHE PHE A . n A 1 21 SER 21 17 17 SER SER A . n A 1 22 ASN 22 18 18 ASN ASN A . n A 1 23 SER 23 19 19 SER SER A . n A 1 24 THR 24 20 20 THR THR A . n A 1 25 GLY 25 21 21 GLY GLY A . n A 1 26 ALA 26 22 22 ALA ALA A . n A 1 27 GLU 27 23 23 GLU GLU A . n A 1 28 ILE 28 24 24 ILE ILE A . n A 1 29 GLU 29 25 25 GLU GLU A . n A 1 30 CYS 30 26 26 CYS CYS A . n A 1 31 LYS 31 27 27 LYS LYS A . n A 1 32 ALA 32 28 28 ALA ALA A . n A 1 33 SER 33 29 29 SER SER A . n A 1 34 GLY 34 30 30 GLY GLY A . n A 1 35 ASN 35 31 31 ASN ASN A . n A 1 36 PRO 36 32 32 PRO PRO A . n A 1 37 MET 37 33 33 MET MET A . n A 1 38 PRO 38 34 34 PRO PRO A . n A 1 39 GLU 39 35 35 GLU GLU A . n A 1 40 ILE 40 36 36 ILE ILE A . n A 1 41 ILE 41 37 37 ILE ILE A . n A 1 42 TRP 42 38 38 TRP TRP A . n A 1 43 ILE 43 39 39 ILE ILE A . n A 1 44 ARG 44 40 40 ARG ARG A . n A 1 45 SER 45 41 41 SER SER A . n A 1 46 ASP 46 42 42 ASP ASP A . n A 1 47 GLY 47 43 43 GLY GLY A . n A 1 48 THR 48 44 44 THR THR A . n A 1 49 ALA 49 45 45 ALA ALA A . n A 1 50 VAL 50 46 46 VAL VAL A . n A 1 51 GLY 51 47 47 GLY GLY A . n A 1 52 ASP 52 48 48 ASP ASP A . n A 1 53 VAL 53 49 49 VAL VAL A . n A 1 54 PRO 54 50 50 PRO PRO A . n A 1 55 GLY 55 51 51 GLY GLY A . n A 1 56 LEU 56 52 52 LEU LEU A . n A 1 57 ARG 57 53 53 ARG ARG A . n A 1 58 GLN 58 54 54 GLN GLN A . n A 1 59 ILE 59 55 55 ILE ILE A . n A 1 60 SER 60 56 56 SER SER A . n A 1 61 SER 61 57 57 SER SER A . n A 1 62 ASP 62 58 58 ASP ASP A . n A 1 63 GLY 63 59 59 GLY GLY A . n A 1 64 LYS 64 60 60 LYS LYS A . n A 1 65 LEU 65 61 61 LEU LEU A . n A 1 66 VAL 66 62 62 VAL VAL A . n A 1 67 PHE 67 63 63 PHE PHE A . n A 1 68 PRO 68 64 64 PRO PRO A . n A 1 69 PRO 69 65 65 PRO PRO A . n A 1 70 PHE 70 66 66 PHE PHE A . n A 1 71 ARG 71 67 67 ARG ARG A . n A 1 72 ALA 72 68 68 ALA ALA A . n A 1 73 GLU 73 69 69 GLU GLU A . n A 1 74 ASP 74 70 70 ASP ASP A . n A 1 75 TYR 75 71 71 TYR TYR A . n A 1 76 ARG 76 72 72 ARG ARG A . n A 1 77 GLN 77 73 73 GLN GLN A . n A 1 78 GLU 78 74 74 GLU GLU A . n A 1 79 VAL 79 75 75 VAL VAL A . n A 1 80 HIS 80 76 76 HIS HIS A . n A 1 81 ALA 81 77 77 ALA ALA A . n A 1 82 GLN 82 78 78 GLN GLN A . n A 1 83 VAL 83 79 79 VAL VAL A . n A 1 84 TYR 84 80 80 TYR TYR A . n A 1 85 ALA 85 81 81 ALA ALA A . n A 1 86 CYS 86 82 82 CYS CYS A . n A 1 87 LEU 87 83 83 LEU LEU A . n A 1 88 ALA 88 84 84 ALA ALA A . n A 1 89 ARG 89 85 85 ARG ARG A . n A 1 90 ASN 90 86 86 ASN ASN A . n A 1 91 GLN 91 87 87 GLN GLN A . n A 1 92 PHE 92 88 88 PHE PHE A . n A 1 93 GLY 93 89 89 GLY GLY A . n A 1 94 SER 94 90 90 SER SER A . n A 1 95 ILE 95 91 91 ILE ILE A . n A 1 96 ILE 96 92 92 ILE ILE A . n A 1 97 SER 97 93 93 SER SER A . n A 1 98 ARG 98 94 94 ARG ARG A . n A 1 99 ASP 99 95 95 ASP ASP A . n A 1 100 VAL 100 96 96 VAL VAL A . n A 1 101 HIS 101 97 97 HIS HIS A . n A 1 102 VAL 102 98 98 VAL VAL A . n A 1 103 ARG 103 99 99 ARG ARG A . n A 1 104 ALA 104 100 100 ALA ALA A . n A 1 105 VAL 105 101 101 VAL VAL A . n A 1 106 VAL 106 102 102 VAL VAL A . n A 1 107 ILE 107 103 103 ILE ILE A . n A 1 108 GLN 108 104 104 GLN GLN A . n A 1 109 SER 109 105 105 SER SER A . n A 1 110 TYR 110 106 106 TYR TYR A . n A 1 111 GLU 111 107 107 GLU GLU A . n A 1 112 SER 112 108 108 SER SER A . n A 1 113 GLU 113 109 109 GLU GLU A . n A 1 114 ALA 114 110 110 ALA ALA A . n A 1 115 ASP 115 111 111 ASP ASP A . n A 1 116 ASN 116 112 112 ASN ASN A . n A 1 117 GLU 117 113 113 GLU GLU A . n A 1 118 TYR 118 114 114 TYR TYR A . n A 1 119 VAL 119 115 115 VAL VAL A . n A 1 120 ILE 120 116 116 ILE ILE A . n A 1 121 ARG 121 117 117 ARG ARG A . n A 1 122 GLY 122 118 118 GLY GLY A . n A 1 123 ASN 123 119 119 ASN ASN A . n A 1 124 SER 124 120 120 SER SER A . n A 1 125 VAL 125 121 121 VAL VAL A . n A 1 126 VAL 126 122 122 VAL VAL A . n A 1 127 MET 127 123 123 MET MET A . n A 1 128 LYS 128 124 124 LYS LYS A . n A 1 129 CYS 129 125 125 CYS CYS A . n A 1 130 GLU 130 126 126 GLU GLU A . n A 1 131 ILE 131 127 127 ILE ILE A . n A 1 132 PRO 132 128 128 PRO PRO A . n A 1 133 SER 133 129 129 SER SER A . n A 1 134 TYR 134 130 130 TYR TYR A . n A 1 135 VAL 135 131 131 VAL VAL A . n A 1 136 ALA 136 132 132 ALA ALA A . n A 1 137 ASP 137 133 133 ASP ASP A . n A 1 138 PHE 138 134 134 PHE PHE A . n A 1 139 VAL 139 135 135 VAL VAL A . n A 1 140 PHE 140 136 136 PHE PHE A . n A 1 141 VAL 141 137 137 VAL VAL A . n A 1 142 ASP 142 138 138 ASP ASP A . n A 1 143 LEU 143 139 139 LEU LEU A . n A 1 144 TRP 144 140 140 TRP TRP A . n A 1 145 LEU 145 141 141 LEU LEU A . n A 1 146 ASP 146 142 142 ASP ASP A . n A 1 147 SER 147 143 143 SER SER A . n A 1 148 GLU 148 144 144 GLU GLU A . n A 1 149 GLY 149 145 145 GLY GLY A . n A 1 150 ARG 150 146 146 ARG ARG A . n A 1 151 ASN 151 147 147 ASN ASN A . n A 1 152 TYR 152 148 148 TYR TYR A . n A 1 153 TYR 153 149 149 TYR TYR A . n A 1 154 PRO 154 150 150 PRO PRO A . n A 1 155 ASN 155 151 151 ASN ASN A . n A 1 156 ASN 156 152 152 ASN ASN A . n A 1 157 ALA 157 153 153 ALA ALA A . n A 1 158 ALA 158 154 154 ALA ALA A . n A 1 159 GLU 159 155 155 GLU GLU A . n A 1 160 THR 160 156 156 THR THR A . n A 1 161 ASP 161 157 157 ASP ASP A . n A 1 162 GLY 162 158 158 GLY GLY A . n A 1 163 LYS 163 159 159 LYS LYS A . n A 1 164 TYR 164 160 160 TYR TYR A . n A 1 165 LEU 165 161 161 LEU LEU A . n A 1 166 VAL 166 162 162 VAL VAL A . n A 1 167 LEU 167 163 163 LEU LEU A . n A 1 168 PRO 168 164 164 PRO PRO A . n A 1 169 SER 169 165 165 SER SER A . n A 1 170 GLY 170 166 166 GLY GLY A . n A 1 171 GLU 171 167 167 GLU GLU A . n A 1 172 LEU 172 168 168 LEU LEU A . n A 1 173 HIS 173 169 169 HIS HIS A . n A 1 174 ILE 174 170 170 ILE ILE A . n A 1 175 ARG 175 171 171 ARG ARG A . n A 1 176 GLU 176 172 172 GLU GLU A . n A 1 177 VAL 177 173 173 VAL VAL A . n A 1 178 GLY 178 174 174 GLY GLY A . n A 1 179 PRO 179 175 175 PRO PRO A . n A 1 180 GLU 180 176 176 GLU GLU A . n A 1 181 ASP 181 177 177 ASP ASP A . n A 1 182 GLY 182 178 178 GLY GLY A . n A 1 183 TYR 183 179 179 TYR TYR A . n A 1 184 LYS 184 180 180 LYS LYS A . n A 1 185 SER 185 181 181 SER SER A . n A 1 186 TYR 186 182 182 TYR TYR A . n A 1 187 GLN 187 183 183 GLN GLN A . n A 1 188 CYS 188 184 184 CYS CYS A . n A 1 189 ARG 189 185 185 ARG ARG A . n A 1 190 THR 190 186 186 THR THR A . n A 1 191 LYS 191 187 187 LYS LYS A . n A 1 192 HIS 192 188 188 HIS HIS A . n A 1 193 ARG 193 189 189 ARG ARG A . n A 1 194 LEU 194 190 190 LEU LEU A . n A 1 195 THR 195 191 191 THR THR A . n A 1 196 GLY 196 192 192 GLY GLY A . n A 1 197 GLU 197 193 193 GLU GLU A . n A 1 198 THR 198 194 194 THR THR A . n A 1 199 ARG 199 195 195 ARG ARG A . n A 1 200 LEU 200 196 196 LEU LEU A . n A 1 201 SER 201 197 197 SER SER A . n A 1 202 ALA 202 198 198 ALA ALA A . n A 1 203 THR 203 199 199 THR THR A . n A 1 204 LYS 204 200 200 LYS LYS A . n A 1 205 GLY 205 201 201 GLY GLY A . n A 1 206 ARG 206 202 202 ARG ARG A . n A 1 207 LEU 207 203 203 LEU LEU A . n A 1 208 VAL 208 204 204 VAL VAL A . n A 1 209 ILE 209 205 205 ILE ILE A . n A 1 210 THR 210 206 206 THR THR A . n A 1 211 GLU 211 207 207 GLU GLU A . n A 1 212 PRO 212 208 208 PRO PRO A . n A 1 213 VAL 213 209 209 VAL VAL A . n A 1 214 GLY 214 210 210 GLY GLY A . n A 1 215 SER 215 211 211 SER SER A . n A 1 216 LYS 216 212 212 LYS LYS A . n A 1 217 ALA 217 213 213 ALA ALA A . n A 1 218 PRO 218 214 214 PRO PRO A . n A 1 219 THR 219 215 215 THR THR A . n A 1 220 PHE 220 216 216 PHE PHE A . n A 1 221 ALA 221 217 217 ALA ALA A . n A 1 222 THR 222 218 218 THR THR A . n A 1 223 ALA 223 219 219 ALA ALA A . n A 1 224 SER 224 220 220 SER SER A . n A 1 225 LYS 225 221 221 LYS LYS A . n A 1 226 ILE 226 222 222 ILE ILE A . n A 1 227 SER 227 223 223 SER SER A . n A 1 228 SER 228 224 224 SER SER A . n A 1 229 LEU 229 225 225 LEU LEU A . n A 1 230 LEU 230 226 226 LEU LEU A . n A 1 231 GLY 231 227 227 GLY GLY A . n A 1 232 SER 232 228 228 SER SER A . n A 1 233 SER 233 229 229 SER SER A . n A 1 234 SER 234 230 230 SER SER A . n A 1 235 SER 235 231 231 SER SER A . n A 1 236 ASP 236 232 232 ASP ASP A . n A 1 237 ILE 237 233 233 ILE ILE A . n A 1 238 VAL 238 234 234 VAL VAL A . n A 1 239 LEU 239 235 235 LEU LEU A . n A 1 240 LEU 240 236 236 LEU LEU A . n A 1 241 CYS 241 237 237 CYS CYS A . n A 1 242 GLN 242 238 238 GLN GLN A . n A 1 243 ALA 243 239 239 ALA ALA A . n A 1 244 GLN 244 240 240 GLN GLN A . n A 1 245 ALA 245 241 241 ALA ALA A . n A 1 246 PHE 246 242 242 PHE PHE A . n A 1 247 PRO 247 243 243 PRO PRO A . n A 1 248 VAL 248 244 244 VAL VAL A . n A 1 249 PRO 249 245 245 PRO PRO A . n A 1 250 TYR 250 246 246 TYR TYR A . n A 1 251 THR 251 247 247 THR THR A . n A 1 252 ARG 252 248 248 ARG ARG A . n A 1 253 TRP 253 249 249 TRP TRP A . n A 1 254 TYR 254 250 250 TYR TYR A . n A 1 255 LYS 255 251 251 LYS LYS A . n A 1 256 PHE 256 252 252 PHE PHE A . n A 1 257 ILE 257 253 253 ILE ILE A . n A 1 258 GLU 258 254 254 GLU GLU A . n A 1 259 GLY 259 255 255 GLY GLY A . n A 1 260 THR 260 256 256 THR THR A . n A 1 261 THR 261 257 257 THR THR A . n A 1 262 ARG 262 258 258 ARG ARG A . n A 1 263 LYS 263 259 259 LYS LYS A . n A 1 264 GLN 264 260 260 GLN GLN A . n A 1 265 ALA 265 261 261 ALA ALA A . n A 1 266 VAL 266 262 262 VAL VAL A . n A 1 267 VAL 267 263 263 VAL VAL A . n A 1 268 LEU 268 264 264 LEU LEU A . n A 1 269 ASN 269 265 265 ASN ASN A . n A 1 270 ASP 270 266 266 ASP ASP A . n A 1 271 ARG 271 267 267 ARG ARG A . n A 1 272 VAL 272 268 268 VAL VAL A . n A 1 273 LYS 273 269 269 LYS LYS A . n A 1 274 GLN 274 270 270 GLN GLN A . n A 1 275 VAL 275 271 271 VAL VAL A . n A 1 276 SER 276 272 272 SER SER A . n A 1 277 GLY 277 273 273 GLY GLY A . n A 1 278 THR 278 274 274 THR THR A . n A 1 279 LEU 279 275 275 LEU LEU A . n A 1 280 ILE 280 276 276 ILE ILE A . n A 1 281 ILE 281 277 277 ILE ILE A . n A 1 282 LYS 282 278 278 LYS LYS A . n A 1 283 ASP 283 279 279 ASP ASP A . n A 1 284 ALA 284 280 280 ALA ALA A . n A 1 285 VAL 285 281 281 VAL VAL A . n A 1 286 VAL 286 282 282 VAL VAL A . n A 1 287 GLU 287 283 283 GLU GLU A . n A 1 288 ASP 288 284 284 ASP ASP A . n A 1 289 SER 289 285 285 SER SER A . n A 1 290 GLY 290 286 286 GLY GLY A . n A 1 291 LYS 291 287 287 LYS LYS A . n A 1 292 TYR 292 288 288 TYR TYR A . n A 1 293 LEU 293 289 289 LEU LEU A . n A 1 294 CYS 294 290 290 CYS CYS A . n A 1 295 VAL 295 291 291 VAL VAL A . n A 1 296 VAL 296 292 292 VAL VAL A . n A 1 297 ASN 297 293 293 ASN ASN A . n A 1 298 ASN 298 294 294 ASN ASN A . n A 1 299 SER 299 295 295 SER SER A . n A 1 300 VAL 300 296 296 VAL VAL A . n A 1 301 GLY 301 297 297 GLY GLY A . n A 1 302 GLY 302 298 298 GLY GLY A . n A 1 303 GLU 303 299 299 GLU GLU A . n A 1 304 SER 304 300 300 SER SER A . n A 1 305 VAL 305 301 301 VAL VAL A . n A 1 306 GLU 306 302 302 GLU GLU A . n A 1 307 THR 307 303 303 THR THR A . n A 1 308 VAL 308 304 304 VAL VAL A . n A 1 309 LEU 309 305 305 LEU LEU A . n A 1 310 THR 310 306 306 THR THR A . n A 1 311 VAL 311 307 307 VAL VAL A . n A 1 312 THR 312 308 308 THR THR A . n A 1 313 ALA 313 309 309 ALA ALA A . n A 1 314 PRO 314 310 310 PRO PRO A . n A 1 315 LEU 315 311 311 LEU LEU A . n A 1 316 SER 316 312 312 SER SER A . n A 1 317 ALA 317 313 313 ALA ALA A . n A 1 318 LYS 318 314 314 LYS LYS A . n A 1 319 ILE 319 315 315 ILE ILE A . n A 1 320 ASP 320 316 316 ASP ASP A . n A 1 321 PRO 321 317 317 PRO PRO A . n A 1 322 PRO 322 318 318 PRO PRO A . n A 1 323 THR 323 319 319 THR THR A . n A 1 324 GLN 324 320 320 GLN GLN A . n A 1 325 THR 325 321 321 THR THR A . n A 1 326 VAL 326 322 322 VAL VAL A . n A 1 327 ASP 327 323 323 ASP ASP A . n A 1 328 PHE 328 324 324 PHE PHE A . n A 1 329 GLY 329 325 325 GLY GLY A . n A 1 330 ARG 330 326 326 ARG ARG A . n A 1 331 PRO 331 327 327 PRO PRO A . n A 1 332 ALA 332 328 328 ALA ALA A . n A 1 333 VAL 333 329 329 VAL VAL A . n A 1 334 PHE 334 330 330 PHE PHE A . n A 1 335 THR 335 331 331 THR THR A . n A 1 336 CYS 336 332 332 CYS CYS A . n A 1 337 GLN 337 333 333 GLN GLN A . n A 1 338 TYR 338 334 334 TYR TYR A . n A 1 339 THR 339 335 335 THR THR A . n A 1 340 GLY 340 336 336 GLY GLY A . n A 1 341 ASN 341 337 337 ASN ASN A . n A 1 342 PRO 342 338 338 PRO PRO A . n A 1 343 ILE 343 339 339 ILE ILE A . n A 1 344 LYS 344 340 340 LYS LYS A . n A 1 345 THR 345 341 341 THR THR A . n A 1 346 VAL 346 342 342 VAL VAL A . n A 1 347 SER 347 343 343 SER SER A . n A 1 348 TRP 348 344 344 TRP TRP A . n A 1 349 MET 349 345 345 MET MET A . n A 1 350 LYS 350 346 346 LYS LYS A . n A 1 351 ASP 351 347 347 ASP ASP A . n A 1 352 GLY 352 348 348 GLY GLY A . n A 1 353 LYS 353 349 349 LYS LYS A . n A 1 354 ALA 354 350 350 ALA ALA A . n A 1 355 ILE 355 351 351 ILE ILE A . n A 1 356 GLY 356 352 352 GLY GLY A . n A 1 357 HIS 357 353 353 HIS HIS A . n A 1 358 SER 358 354 354 SER SER A . n A 1 359 GLU 359 355 355 GLU GLU A . n A 1 360 PRO 360 356 356 PRO PRO A . n A 1 361 VAL 361 357 357 VAL VAL A . n A 1 362 LEU 362 358 358 LEU LEU A . n A 1 363 ARG 363 359 359 ARG ARG A . n A 1 364 ILE 364 360 360 ILE ILE A . n A 1 365 GLU 365 361 361 GLU GLU A . n A 1 366 SER 366 362 362 SER SER A . n A 1 367 VAL 367 363 363 VAL VAL A . n A 1 368 LYS 368 364 364 LYS LYS A . n A 1 369 LYS 369 365 365 LYS LYS A . n A 1 370 GLU 370 366 366 GLU GLU A . n A 1 371 ASP 371 367 367 ASP ASP A . n A 1 372 LYS 372 368 368 LYS LYS A . n A 1 373 GLY 373 369 369 GLY GLY A . n A 1 374 MET 374 370 370 MET MET A . n A 1 375 TYR 375 371 371 TYR TYR A . n A 1 376 GLN 376 372 372 GLN GLN A . n A 1 377 CYS 377 373 373 CYS CYS A . n A 1 378 PHE 378 374 374 PHE PHE A . n A 1 379 VAL 379 375 375 VAL VAL A . n A 1 380 ARG 380 376 376 ARG ARG A . n A 1 381 ASN 381 377 377 ASN ASN A . n A 1 382 ASP 382 378 378 ASP ASP A . n A 1 383 GLN 383 379 379 GLN GLN A . n A 1 384 GLU 384 380 380 GLU GLU A . n A 1 385 SER 385 381 381 SER SER A . n A 1 386 ALA 386 382 382 ALA ALA A . n A 1 387 GLU 387 383 383 GLU GLU A . n A 1 388 ALA 388 384 384 ALA ALA A . n A 1 389 SER 389 385 385 SER SER A . n A 1 390 ALA 390 386 386 ALA ALA A . n A 1 391 GLU 391 387 387 GLU GLU A . n A 1 392 LEU 392 388 388 LEU LEU A . n A 1 393 LYS 393 389 389 LYS LYS A . n A 1 394 LEU 394 390 390 LEU LEU A . n A 1 395 GLY 395 391 391 GLY GLY A . n A 1 396 GLY 396 392 ? ? ? A . n B 1 1 GLY 1 -3 ? ? ? B . n B 1 2 GLY 2 -2 ? ? ? B . n B 1 3 ALA 3 -1 ? ? ? B . n B 1 4 ASP 4 0 ? ? ? B . n B 1 5 GLN 5 1 1 GLN GLN B . n B 1 6 LYS 6 2 2 LYS LYS B . n B 1 7 GLY 7 3 3 GLY GLY B . n B 1 8 PRO 8 4 4 PRO PRO B . n B 1 9 VAL 9 5 5 VAL VAL B . n B 1 10 PHE 10 6 6 PHE PHE B . n B 1 11 LEU 11 7 7 LEU LEU B . n B 1 12 LYS 12 8 8 LYS LYS B . n B 1 13 GLU 13 9 9 GLU GLU B . n B 1 14 PRO 14 10 10 PRO PRO B . n B 1 15 THR 15 11 11 THR THR B . n B 1 16 ASN 16 12 12 ASN ASN B . n B 1 17 ARG 17 13 13 ARG ARG B . n B 1 18 ILE 18 14 14 ILE ILE B . n B 1 19 ASP 19 15 15 ASP ASP B . n B 1 20 PHE 20 16 16 PHE PHE B . n B 1 21 SER 21 17 17 SER SER B . n B 1 22 ASN 22 18 18 ASN ASN B . n B 1 23 SER 23 19 19 SER SER B . n B 1 24 THR 24 20 20 THR THR B . n B 1 25 GLY 25 21 21 GLY GLY B . n B 1 26 ALA 26 22 22 ALA ALA B . n B 1 27 GLU 27 23 23 GLU GLU B . n B 1 28 ILE 28 24 24 ILE ILE B . n B 1 29 GLU 29 25 25 GLU GLU B . n B 1 30 CYS 30 26 26 CYS CYS B . n B 1 31 LYS 31 27 27 LYS LYS B . n B 1 32 ALA 32 28 28 ALA ALA B . n B 1 33 SER 33 29 29 SER SER B . n B 1 34 GLY 34 30 30 GLY GLY B . n B 1 35 ASN 35 31 31 ASN ASN B . n B 1 36 PRO 36 32 32 PRO PRO B . n B 1 37 MET 37 33 33 MET MET B . n B 1 38 PRO 38 34 34 PRO PRO B . n B 1 39 GLU 39 35 35 GLU GLU B . n B 1 40 ILE 40 36 36 ILE ILE B . n B 1 41 ILE 41 37 37 ILE ILE B . n B 1 42 TRP 42 38 38 TRP TRP B . n B 1 43 ILE 43 39 39 ILE ILE B . n B 1 44 ARG 44 40 40 ARG ARG B . n B 1 45 SER 45 41 41 SER SER B . n B 1 46 ASP 46 42 42 ASP ASP B . n B 1 47 GLY 47 43 43 GLY GLY B . n B 1 48 THR 48 44 44 THR THR B . n B 1 49 ALA 49 45 45 ALA ALA B . n B 1 50 VAL 50 46 46 VAL VAL B . n B 1 51 GLY 51 47 47 GLY GLY B . n B 1 52 ASP 52 48 48 ASP ASP B . n B 1 53 VAL 53 49 49 VAL VAL B . n B 1 54 PRO 54 50 50 PRO PRO B . n B 1 55 GLY 55 51 51 GLY GLY B . n B 1 56 LEU 56 52 52 LEU LEU B . n B 1 57 ARG 57 53 53 ARG ARG B . n B 1 58 GLN 58 54 54 GLN GLN B . n B 1 59 ILE 59 55 55 ILE ILE B . n B 1 60 SER 60 56 56 SER SER B . n B 1 61 SER 61 57 57 SER SER B . n B 1 62 ASP 62 58 58 ASP ASP B . n B 1 63 GLY 63 59 59 GLY GLY B . n B 1 64 LYS 64 60 60 LYS LYS B . n B 1 65 LEU 65 61 61 LEU LEU B . n B 1 66 VAL 66 62 62 VAL VAL B . n B 1 67 PHE 67 63 63 PHE PHE B . n B 1 68 PRO 68 64 64 PRO PRO B . n B 1 69 PRO 69 65 65 PRO PRO B . n B 1 70 PHE 70 66 66 PHE PHE B . n B 1 71 ARG 71 67 67 ARG ARG B . n B 1 72 ALA 72 68 68 ALA ALA B . n B 1 73 GLU 73 69 69 GLU GLU B . n B 1 74 ASP 74 70 70 ASP ASP B . n B 1 75 TYR 75 71 71 TYR TYR B . n B 1 76 ARG 76 72 72 ARG ARG B . n B 1 77 GLN 77 73 73 GLN GLN B . n B 1 78 GLU 78 74 74 GLU GLU B . n B 1 79 VAL 79 75 75 VAL VAL B . n B 1 80 HIS 80 76 76 HIS HIS B . n B 1 81 ALA 81 77 77 ALA ALA B . n B 1 82 GLN 82 78 78 GLN GLN B . n B 1 83 VAL 83 79 79 VAL VAL B . n B 1 84 TYR 84 80 80 TYR TYR B . n B 1 85 ALA 85 81 81 ALA ALA B . n B 1 86 CYS 86 82 82 CYS CYS B . n B 1 87 LEU 87 83 83 LEU LEU B . n B 1 88 ALA 88 84 84 ALA ALA B . n B 1 89 ARG 89 85 85 ARG ARG B . n B 1 90 ASN 90 86 86 ASN ASN B . n B 1 91 GLN 91 87 87 GLN GLN B . n B 1 92 PHE 92 88 88 PHE PHE B . n B 1 93 GLY 93 89 89 GLY GLY B . n B 1 94 SER 94 90 90 SER SER B . n B 1 95 ILE 95 91 91 ILE ILE B . n B 1 96 ILE 96 92 92 ILE ILE B . n B 1 97 SER 97 93 93 SER SER B . n B 1 98 ARG 98 94 94 ARG ARG B . n B 1 99 ASP 99 95 95 ASP ASP B . n B 1 100 VAL 100 96 96 VAL VAL B . n B 1 101 HIS 101 97 97 HIS HIS B . n B 1 102 VAL 102 98 98 VAL VAL B . n B 1 103 ARG 103 99 99 ARG ARG B . n B 1 104 ALA 104 100 100 ALA ALA B . n B 1 105 VAL 105 101 101 VAL VAL B . n B 1 106 VAL 106 102 102 VAL VAL B . n B 1 107 ILE 107 103 103 ILE ILE B . n B 1 108 GLN 108 104 104 GLN GLN B . n B 1 109 SER 109 105 105 SER SER B . n B 1 110 TYR 110 106 106 TYR TYR B . n B 1 111 GLU 111 107 107 GLU GLU B . n B 1 112 SER 112 108 108 SER SER B . n B 1 113 GLU 113 109 109 GLU GLU B . n B 1 114 ALA 114 110 110 ALA ALA B . n B 1 115 ASP 115 111 111 ASP ASP B . n B 1 116 ASN 116 112 112 ASN ASN B . n B 1 117 GLU 117 113 113 GLU GLU B . n B 1 118 TYR 118 114 114 TYR TYR B . n B 1 119 VAL 119 115 115 VAL VAL B . n B 1 120 ILE 120 116 116 ILE ILE B . n B 1 121 ARG 121 117 117 ARG ARG B . n B 1 122 GLY 122 118 118 GLY GLY B . n B 1 123 ASN 123 119 119 ASN ASN B . n B 1 124 SER 124 120 120 SER SER B . n B 1 125 VAL 125 121 121 VAL VAL B . n B 1 126 VAL 126 122 122 VAL VAL B . n B 1 127 MET 127 123 123 MET MET B . n B 1 128 LYS 128 124 124 LYS LYS B . n B 1 129 CYS 129 125 125 CYS CYS B . n B 1 130 GLU 130 126 126 GLU GLU B . n B 1 131 ILE 131 127 127 ILE ILE B . n B 1 132 PRO 132 128 128 PRO PRO B . n B 1 133 SER 133 129 129 SER SER B . n B 1 134 TYR 134 130 130 TYR TYR B . n B 1 135 VAL 135 131 131 VAL VAL B . n B 1 136 ALA 136 132 132 ALA ALA B . n B 1 137 ASP 137 133 133 ASP ASP B . n B 1 138 PHE 138 134 134 PHE PHE B . n B 1 139 VAL 139 135 135 VAL VAL B . n B 1 140 PHE 140 136 136 PHE PHE B . n B 1 141 VAL 141 137 137 VAL VAL B . n B 1 142 ASP 142 138 138 ASP ASP B . n B 1 143 LEU 143 139 139 LEU LEU B . n B 1 144 TRP 144 140 140 TRP TRP B . n B 1 145 LEU 145 141 141 LEU LEU B . n B 1 146 ASP 146 142 142 ASP ASP B . n B 1 147 SER 147 143 143 SER SER B . n B 1 148 GLU 148 144 144 GLU GLU B . n B 1 149 GLY 149 145 145 GLY GLY B . n B 1 150 ARG 150 146 146 ARG ARG B . n B 1 151 ASN 151 147 147 ASN ASN B . n B 1 152 TYR 152 148 148 TYR TYR B . n B 1 153 TYR 153 149 149 TYR TYR B . n B 1 154 PRO 154 150 150 PRO PRO B . n B 1 155 ASN 155 151 151 ASN ASN B . n B 1 156 ASN 156 152 152 ASN ASN B . n B 1 157 ALA 157 153 ? ? ? B . n B 1 158 ALA 158 154 ? ? ? B . n B 1 159 GLU 159 155 ? ? ? B . n B 1 160 THR 160 156 ? ? ? B . n B 1 161 ASP 161 157 157 ASP ASP B . n B 1 162 GLY 162 158 158 GLY GLY B . n B 1 163 LYS 163 159 159 LYS LYS B . n B 1 164 TYR 164 160 160 TYR TYR B . n B 1 165 LEU 165 161 161 LEU LEU B . n B 1 166 VAL 166 162 162 VAL VAL B . n B 1 167 LEU 167 163 163 LEU LEU B . n B 1 168 PRO 168 164 164 PRO PRO B . n B 1 169 SER 169 165 165 SER SER B . n B 1 170 GLY 170 166 166 GLY GLY B . n B 1 171 GLU 171 167 167 GLU GLU B . n B 1 172 LEU 172 168 168 LEU LEU B . n B 1 173 HIS 173 169 169 HIS HIS B . n B 1 174 ILE 174 170 170 ILE ILE B . n B 1 175 ARG 175 171 171 ARG ARG B . n B 1 176 GLU 176 172 172 GLU GLU B . n B 1 177 VAL 177 173 173 VAL VAL B . n B 1 178 GLY 178 174 174 GLY GLY B . n B 1 179 PRO 179 175 175 PRO PRO B . n B 1 180 GLU 180 176 176 GLU GLU B . n B 1 181 ASP 181 177 177 ASP ASP B . n B 1 182 GLY 182 178 178 GLY GLY B . n B 1 183 TYR 183 179 179 TYR TYR B . n B 1 184 LYS 184 180 180 LYS LYS B . n B 1 185 SER 185 181 181 SER SER B . n B 1 186 TYR 186 182 182 TYR TYR B . n B 1 187 GLN 187 183 183 GLN GLN B . n B 1 188 CYS 188 184 184 CYS CYS B . n B 1 189 ARG 189 185 185 ARG ARG B . n B 1 190 THR 190 186 186 THR THR B . n B 1 191 LYS 191 187 187 LYS LYS B . n B 1 192 HIS 192 188 188 HIS HIS B . n B 1 193 ARG 193 189 189 ARG ARG B . n B 1 194 LEU 194 190 190 LEU LEU B . n B 1 195 THR 195 191 191 THR THR B . n B 1 196 GLY 196 192 192 GLY GLY B . n B 1 197 GLU 197 193 193 GLU GLU B . n B 1 198 THR 198 194 194 THR THR B . n B 1 199 ARG 199 195 195 ARG ARG B . n B 1 200 LEU 200 196 196 LEU LEU B . n B 1 201 SER 201 197 197 SER SER B . n B 1 202 ALA 202 198 198 ALA ALA B . n B 1 203 THR 203 199 199 THR THR B . n B 1 204 LYS 204 200 200 LYS LYS B . n B 1 205 GLY 205 201 201 GLY GLY B . n B 1 206 ARG 206 202 202 ARG ARG B . n B 1 207 LEU 207 203 203 LEU LEU B . n B 1 208 VAL 208 204 204 VAL VAL B . n B 1 209 ILE 209 205 205 ILE ILE B . n B 1 210 THR 210 206 206 THR THR B . n B 1 211 GLU 211 207 207 GLU GLU B . n B 1 212 PRO 212 208 208 PRO PRO B . n B 1 213 VAL 213 209 209 VAL VAL B . n B 1 214 GLY 214 210 210 GLY GLY B . n B 1 215 SER 215 211 211 SER SER B . n B 1 216 LYS 216 212 212 LYS LYS B . n B 1 217 ALA 217 213 213 ALA ALA B . n B 1 218 PRO 218 214 214 PRO PRO B . n B 1 219 THR 219 215 215 THR THR B . n B 1 220 PHE 220 216 216 PHE PHE B . n B 1 221 ALA 221 217 217 ALA ALA B . n B 1 222 THR 222 218 218 THR THR B . n B 1 223 ALA 223 219 219 ALA ALA B . n B 1 224 SER 224 220 220 SER SER B . n B 1 225 LYS 225 221 221 LYS LYS B . n B 1 226 ILE 226 222 222 ILE ILE B . n B 1 227 SER 227 223 223 SER SER B . n B 1 228 SER 228 224 224 SER SER B . n B 1 229 LEU 229 225 225 LEU LEU B . n B 1 230 LEU 230 226 226 LEU LEU B . n B 1 231 GLY 231 227 227 GLY GLY B . n B 1 232 SER 232 228 228 SER SER B . n B 1 233 SER 233 229 229 SER SER B . n B 1 234 SER 234 230 230 SER SER B . n B 1 235 SER 235 231 231 SER SER B . n B 1 236 ASP 236 232 232 ASP ASP B . n B 1 237 ILE 237 233 233 ILE ILE B . n B 1 238 VAL 238 234 234 VAL VAL B . n B 1 239 LEU 239 235 235 LEU LEU B . n B 1 240 LEU 240 236 236 LEU LEU B . n B 1 241 CYS 241 237 237 CYS CYS B . n B 1 242 GLN 242 238 238 GLN GLN B . n B 1 243 ALA 243 239 239 ALA ALA B . n B 1 244 GLN 244 240 240 GLN GLN B . n B 1 245 ALA 245 241 241 ALA ALA B . n B 1 246 PHE 246 242 242 PHE PHE B . n B 1 247 PRO 247 243 243 PRO PRO B . n B 1 248 VAL 248 244 244 VAL VAL B . n B 1 249 PRO 249 245 245 PRO PRO B . n B 1 250 TYR 250 246 246 TYR TYR B . n B 1 251 THR 251 247 247 THR THR B . n B 1 252 ARG 252 248 248 ARG ARG B . n B 1 253 TRP 253 249 249 TRP TRP B . n B 1 254 TYR 254 250 250 TYR TYR B . n B 1 255 LYS 255 251 251 LYS LYS B . n B 1 256 PHE 256 252 252 PHE PHE B . n B 1 257 ILE 257 253 253 ILE ILE B . n B 1 258 GLU 258 254 254 GLU GLU B . n B 1 259 GLY 259 255 255 GLY GLY B . n B 1 260 THR 260 256 256 THR THR B . n B 1 261 THR 261 257 257 THR THR B . n B 1 262 ARG 262 258 258 ARG ARG B . n B 1 263 LYS 263 259 259 LYS LYS B . n B 1 264 GLN 264 260 260 GLN GLN B . n B 1 265 ALA 265 261 261 ALA ALA B . n B 1 266 VAL 266 262 262 VAL VAL B . n B 1 267 VAL 267 263 263 VAL VAL B . n B 1 268 LEU 268 264 264 LEU LEU B . n B 1 269 ASN 269 265 265 ASN ASN B . n B 1 270 ASP 270 266 266 ASP ASP B . n B 1 271 ARG 271 267 267 ARG ARG B . n B 1 272 VAL 272 268 268 VAL VAL B . n B 1 273 LYS 273 269 269 LYS LYS B . n B 1 274 GLN 274 270 270 GLN GLN B . n B 1 275 VAL 275 271 271 VAL VAL B . n B 1 276 SER 276 272 272 SER SER B . n B 1 277 GLY 277 273 273 GLY GLY B . n B 1 278 THR 278 274 274 THR THR B . n B 1 279 LEU 279 275 275 LEU LEU B . n B 1 280 ILE 280 276 276 ILE ILE B . n B 1 281 ILE 281 277 277 ILE ILE B . n B 1 282 LYS 282 278 278 LYS LYS B . n B 1 283 ASP 283 279 279 ASP ASP B . n B 1 284 ALA 284 280 280 ALA ALA B . n B 1 285 VAL 285 281 281 VAL VAL B . n B 1 286 VAL 286 282 282 VAL VAL B . n B 1 287 GLU 287 283 283 GLU GLU B . n B 1 288 ASP 288 284 284 ASP ASP B . n B 1 289 SER 289 285 285 SER SER B . n B 1 290 GLY 290 286 286 GLY GLY B . n B 1 291 LYS 291 287 287 LYS LYS B . n B 1 292 TYR 292 288 288 TYR TYR B . n B 1 293 LEU 293 289 289 LEU LEU B . n B 1 294 CYS 294 290 290 CYS CYS B . n B 1 295 VAL 295 291 291 VAL VAL B . n B 1 296 VAL 296 292 292 VAL VAL B . n B 1 297 ASN 297 293 293 ASN ASN B . n B 1 298 ASN 298 294 294 ASN ASN B . n B 1 299 SER 299 295 295 SER SER B . n B 1 300 VAL 300 296 296 VAL VAL B . n B 1 301 GLY 301 297 297 GLY GLY B . n B 1 302 GLY 302 298 298 GLY GLY B . n B 1 303 GLU 303 299 299 GLU GLU B . n B 1 304 SER 304 300 300 SER SER B . n B 1 305 VAL 305 301 301 VAL VAL B . n B 1 306 GLU 306 302 302 GLU GLU B . n B 1 307 THR 307 303 303 THR THR B . n B 1 308 VAL 308 304 304 VAL VAL B . n B 1 309 LEU 309 305 305 LEU LEU B . n B 1 310 THR 310 306 306 THR THR B . n B 1 311 VAL 311 307 307 VAL VAL B . n B 1 312 THR 312 308 308 THR THR B . n B 1 313 ALA 313 309 309 ALA ALA B . n B 1 314 PRO 314 310 310 PRO PRO B . n B 1 315 LEU 315 311 311 LEU LEU B . n B 1 316 SER 316 312 312 SER SER B . n B 1 317 ALA 317 313 313 ALA ALA B . n B 1 318 LYS 318 314 314 LYS LYS B . n B 1 319 ILE 319 315 315 ILE ILE B . n B 1 320 ASP 320 316 316 ASP ASP B . n B 1 321 PRO 321 317 317 PRO PRO B . n B 1 322 PRO 322 318 318 PRO PRO B . n B 1 323 THR 323 319 319 THR THR B . n B 1 324 GLN 324 320 320 GLN GLN B . n B 1 325 THR 325 321 321 THR THR B . n B 1 326 VAL 326 322 322 VAL VAL B . n B 1 327 ASP 327 323 323 ASP ASP B . n B 1 328 PHE 328 324 324 PHE PHE B . n B 1 329 GLY 329 325 325 GLY GLY B . n B 1 330 ARG 330 326 326 ARG ARG B . n B 1 331 PRO 331 327 327 PRO PRO B . n B 1 332 ALA 332 328 328 ALA ALA B . n B 1 333 VAL 333 329 329 VAL VAL B . n B 1 334 PHE 334 330 330 PHE PHE B . n B 1 335 THR 335 331 331 THR THR B . n B 1 336 CYS 336 332 332 CYS CYS B . n B 1 337 GLN 337 333 333 GLN GLN B . n B 1 338 TYR 338 334 334 TYR TYR B . n B 1 339 THR 339 335 335 THR THR B . n B 1 340 GLY 340 336 336 GLY GLY B . n B 1 341 ASN 341 337 337 ASN ASN B . n B 1 342 PRO 342 338 338 PRO PRO B . n B 1 343 ILE 343 339 339 ILE ILE B . n B 1 344 LYS 344 340 340 LYS LYS B . n B 1 345 THR 345 341 341 THR THR B . n B 1 346 VAL 346 342 342 VAL VAL B . n B 1 347 SER 347 343 343 SER SER B . n B 1 348 TRP 348 344 344 TRP TRP B . n B 1 349 MET 349 345 345 MET MET B . n B 1 350 LYS 350 346 346 LYS LYS B . n B 1 351 ASP 351 347 347 ASP ASP B . n B 1 352 GLY 352 348 348 GLY GLY B . n B 1 353 LYS 353 349 349 LYS LYS B . n B 1 354 ALA 354 350 350 ALA ALA B . n B 1 355 ILE 355 351 351 ILE ILE B . n B 1 356 GLY 356 352 352 GLY GLY B . n B 1 357 HIS 357 353 353 HIS HIS B . n B 1 358 SER 358 354 354 SER SER B . n B 1 359 GLU 359 355 355 GLU GLU B . n B 1 360 PRO 360 356 356 PRO PRO B . n B 1 361 VAL 361 357 357 VAL VAL B . n B 1 362 LEU 362 358 358 LEU LEU B . n B 1 363 ARG 363 359 359 ARG ARG B . n B 1 364 ILE 364 360 360 ILE ILE B . n B 1 365 GLU 365 361 361 GLU GLU B . n B 1 366 SER 366 362 362 SER SER B . n B 1 367 VAL 367 363 363 VAL VAL B . n B 1 368 LYS 368 364 364 LYS LYS B . n B 1 369 LYS 369 365 365 LYS LYS B . n B 1 370 GLU 370 366 366 GLU GLU B . n B 1 371 ASP 371 367 367 ASP ASP B . n B 1 372 LYS 372 368 368 LYS LYS B . n B 1 373 GLY 373 369 369 GLY GLY B . n B 1 374 MET 374 370 370 MET MET B . n B 1 375 TYR 375 371 371 TYR TYR B . n B 1 376 GLN 376 372 372 GLN GLN B . n B 1 377 CYS 377 373 373 CYS CYS B . n B 1 378 PHE 378 374 374 PHE PHE B . n B 1 379 VAL 379 375 375 VAL VAL B . n B 1 380 ARG 380 376 376 ARG ARG B . n B 1 381 ASN 381 377 377 ASN ASN B . n B 1 382 ASP 382 378 378 ASP ASP B . n B 1 383 GLN 383 379 379 GLN GLN B . n B 1 384 GLU 384 380 380 GLU GLU B . n B 1 385 SER 385 381 381 SER SER B . n B 1 386 ALA 386 382 382 ALA ALA B . n B 1 387 GLU 387 383 383 GLU GLU B . n B 1 388 ALA 388 384 384 ALA ALA B . n B 1 389 SER 389 385 385 SER SER B . n B 1 390 ALA 390 386 386 ALA ALA B . n B 1 391 GLU 391 387 387 GLU GLU B . n B 1 392 LEU 392 388 388 LEU LEU B . n B 1 393 LYS 393 389 389 LYS LYS B . n B 1 394 LEU 394 390 390 LEU LEU B . n B 1 395 GLY 395 391 391 GLY GLY B . n B 1 396 GLY 396 392 ? ? ? B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 NAG 1 401 4018 NAG NAG A . D 2 NAG 2 402 4019 NAG NAG A . E 3 BMA 3 403 4020 BMA MAN A . F 4 MAN 4 404 4021 MAN MAN A . G 2 NAG 1 405 4293 NAG NAG A . H 2 NAG 2 406 4294 NAG NAG A . I 5 ZN 1 407 2002 ZN ZN A . J 5 ZN 1 408 2005 ZN ZN A . K 5 ZN 1 409 2006 ZN ZN A . L 5 ZN 1 410 2001 ZN ZN A . M 2 NAG 1 401 4018 NAG NAG B . N 2 NAG 1 402 4293 NAG NAG B . O 2 NAG 2 403 4294 NAG NAG B . P 5 ZN 1 404 2003 ZN ZN B . Q 5 ZN 1 405 2004 ZN ZN B . R 6 HOH 1 501 1 HOH HOH A . R 6 HOH 2 502 1 HOH HOH A . R 6 HOH 3 503 1 HOH HOH A . R 6 HOH 4 504 1 HOH HOH A . R 6 HOH 5 505 5 HOH HOH A . R 6 HOH 6 506 8 HOH HOH A . S 6 HOH 1 501 2 HOH HOH B . S 6 HOH 2 502 1 HOH HOH B . S 6 HOH 3 503 1 HOH HOH B . S 6 HOH 4 504 7 HOH HOH B . S 6 HOH 5 505 6 HOH HOH B . S 6 HOH 6 506 1 HOH HOH B . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 6230 ? 1 MORE -207 ? 1 'SSA (A^2)' 38090 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 OE1 ? A GLU 13 ? A GLU 9 ? 1_555 ZN ? J ZN . ? A ZN 408 ? 1_555 OE2 ? A GLU 13 ? A GLU 9 ? 1_555 64.8 ? 2 OE1 ? A GLU 13 ? A GLU 9 ? 1_555 ZN ? J ZN . ? A ZN 408 ? 1_555 O ? A GLU 387 ? A GLU 383 ? 1_555 139.3 ? 3 OE2 ? A GLU 13 ? A GLU 9 ? 1_555 ZN ? J ZN . ? A ZN 408 ? 1_555 O ? A GLU 387 ? A GLU 383 ? 1_555 148.9 ? 4 OE1 ? A GLU 13 ? A GLU 9 ? 1_555 ZN ? J ZN . ? A ZN 408 ? 1_555 OE1 ? A GLU 387 ? A GLU 383 ? 1_555 51.8 ? 5 OE2 ? A GLU 13 ? A GLU 9 ? 1_555 ZN ? J ZN . ? A ZN 408 ? 1_555 OE1 ? A GLU 387 ? A GLU 383 ? 1_555 91.8 ? 6 O ? A GLU 387 ? A GLU 383 ? 1_555 ZN ? J ZN . ? A ZN 408 ? 1_555 OE1 ? A GLU 387 ? A GLU 383 ? 1_555 94.4 ? 7 OD1 ? A ASP 99 ? A ASP 95 ? 1_555 ZN ? I ZN . ? A ZN 407 ? 1_555 OD2 ? A ASP 99 ? A ASP 95 ? 1_555 66.3 ? 8 OD1 ? A ASP 99 ? A ASP 95 ? 1_555 ZN ? I ZN . ? A ZN 407 ? 1_555 NE2 ? A HIS 101 ? A HIS 97 ? 1_555 52.4 ? 9 OD2 ? A ASP 99 ? A ASP 95 ? 1_555 ZN ? I ZN . ? A ZN 407 ? 1_555 NE2 ? A HIS 101 ? A HIS 97 ? 1_555 118.3 ? 10 OD1 ? A ASP 99 ? A ASP 95 ? 1_555 ZN ? I ZN . ? A ZN 407 ? 1_555 O ? R HOH . ? A HOH 505 ? 1_555 135.9 ? 11 OD2 ? A ASP 99 ? A ASP 95 ? 1_555 ZN ? I ZN . ? A ZN 407 ? 1_555 O ? R HOH . ? A HOH 505 ? 1_555 129.5 ? 12 NE2 ? A HIS 101 ? A HIS 97 ? 1_555 ZN ? I ZN . ? A ZN 407 ? 1_555 O ? R HOH . ? A HOH 505 ? 1_555 94.4 ? 13 OE1 ? A GLU 113 ? A GLU 109 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OE2 ? A GLU 113 ? A GLU 109 ? 1_555 66.4 ? 14 OE1 ? A GLU 113 ? A GLU 109 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OE1 ? A GLU 130 ? A GLU 126 ? 1_555 142.3 ? 15 OE2 ? A GLU 113 ? A GLU 109 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OE1 ? A GLU 130 ? A GLU 126 ? 1_555 101.3 ? 16 OE1 ? A GLU 113 ? A GLU 109 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OE2 ? A GLU 130 ? A GLU 126 ? 1_555 139.1 ? 17 OE2 ? A GLU 113 ? A GLU 109 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OE2 ? A GLU 130 ? A GLU 126 ? 1_555 82.4 ? 18 OE1 ? A GLU 130 ? A GLU 126 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OE2 ? A GLU 130 ? A GLU 126 ? 1_555 66.8 ? 19 OE1 ? A GLU 113 ? A GLU 109 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OD1 ? B ASP 115 ? B ASP 111 ? 1_555 69.1 ? 20 OE2 ? A GLU 113 ? A GLU 109 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OD1 ? B ASP 115 ? B ASP 111 ? 1_555 112.0 ? 21 OE1 ? A GLU 130 ? A GLU 126 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OD1 ? B ASP 115 ? B ASP 111 ? 1_555 143.3 ? 22 OE2 ? A GLU 130 ? A GLU 126 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OD1 ? B ASP 115 ? B ASP 111 ? 1_555 101.7 ? 23 OE1 ? A GLU 113 ? A GLU 109 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OD2 ? B ASP 115 ? B ASP 111 ? 1_555 112.0 ? 24 OE2 ? A GLU 113 ? A GLU 109 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OD2 ? B ASP 115 ? B ASP 111 ? 1_555 178.3 ? 25 OE1 ? A GLU 130 ? A GLU 126 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OD2 ? B ASP 115 ? B ASP 111 ? 1_555 80.1 ? 26 OE2 ? A GLU 130 ? A GLU 126 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OD2 ? B ASP 115 ? B ASP 111 ? 1_555 99.0 ? 27 OD1 ? B ASP 115 ? B ASP 111 ? 1_555 ZN ? K ZN . ? A ZN 409 ? 1_555 OD2 ? B ASP 115 ? B ASP 111 ? 1_555 66.9 ? 28 OD1 ? A ASP 115 ? A ASP 111 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OD2 ? A ASP 115 ? A ASP 111 ? 1_555 66.9 ? 29 OD1 ? A ASP 115 ? A ASP 111 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE1 ? B GLU 113 ? B GLU 109 ? 1_555 96.8 ? 30 OD2 ? A ASP 115 ? A ASP 111 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE1 ? B GLU 113 ? B GLU 109 ? 1_555 149.8 ? 31 OD1 ? A ASP 115 ? A ASP 111 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE2 ? B GLU 113 ? B GLU 109 ? 1_555 56.3 ? 32 OD2 ? A ASP 115 ? A ASP 111 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE2 ? B GLU 113 ? B GLU 109 ? 1_555 116.7 ? 33 OE1 ? B GLU 113 ? B GLU 109 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE2 ? B GLU 113 ? B GLU 109 ? 1_555 66.5 ? 34 OD1 ? A ASP 115 ? A ASP 111 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE1 ? B GLU 130 ? B GLU 126 ? 1_555 122.2 ? 35 OD2 ? A ASP 115 ? A ASP 111 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE1 ? B GLU 130 ? B GLU 126 ? 1_555 103.0 ? 36 OE1 ? B GLU 113 ? B GLU 109 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE1 ? B GLU 130 ? B GLU 126 ? 1_555 63.1 ? 37 OE2 ? B GLU 113 ? B GLU 109 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE1 ? B GLU 130 ? B GLU 126 ? 1_555 128.9 ? 38 OD1 ? A ASP 115 ? A ASP 111 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE2 ? B GLU 130 ? B GLU 126 ? 1_555 144.7 ? 39 OD2 ? A ASP 115 ? A ASP 111 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE2 ? B GLU 130 ? B GLU 126 ? 1_555 77.9 ? 40 OE1 ? B GLU 113 ? B GLU 109 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE2 ? B GLU 130 ? B GLU 126 ? 1_555 115.7 ? 41 OE2 ? B GLU 113 ? B GLU 109 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE2 ? B GLU 130 ? B GLU 126 ? 1_555 148.8 ? 42 OE1 ? B GLU 130 ? B GLU 126 ? 1_555 ZN ? L ZN . ? A ZN 410 ? 1_555 OE2 ? B GLU 130 ? B GLU 126 ? 1_555 66.9 ? 43 OE1 ? B GLU 13 ? B GLU 9 ? 1_555 ZN ? Q ZN . ? B ZN 405 ? 1_555 OE2 ? B GLU 13 ? B GLU 9 ? 1_555 66.9 ? 44 OE1 ? B GLU 13 ? B GLU 9 ? 1_555 ZN ? Q ZN . ? B ZN 405 ? 1_555 O ? B GLU 387 ? B GLU 383 ? 1_555 150.6 ? 45 OE2 ? B GLU 13 ? B GLU 9 ? 1_555 ZN ? Q ZN . ? B ZN 405 ? 1_555 O ? B GLU 387 ? B GLU 383 ? 1_555 130.2 ? 46 OE1 ? B GLU 13 ? B GLU 9 ? 1_555 ZN ? Q ZN . ? B ZN 405 ? 1_555 OE1 ? B GLU 387 ? B GLU 383 ? 1_555 129.6 ? 47 OE2 ? B GLU 13 ? B GLU 9 ? 1_555 ZN ? Q ZN . ? B ZN 405 ? 1_555 OE1 ? B GLU 387 ? B GLU 383 ? 1_555 67.9 ? 48 O ? B GLU 387 ? B GLU 383 ? 1_555 ZN ? Q ZN . ? B ZN 405 ? 1_555 OE1 ? B GLU 387 ? B GLU 383 ? 1_555 78.6 ? 49 OD1 ? B ASP 99 ? B ASP 95 ? 1_555 ZN ? P ZN . ? B ZN 404 ? 1_555 OD2 ? B ASP 99 ? B ASP 95 ? 1_555 66.9 ? 50 OD1 ? B ASP 99 ? B ASP 95 ? 1_555 ZN ? P ZN . ? B ZN 404 ? 1_555 NE2 ? B HIS 101 ? B HIS 97 ? 1_555 73.9 ? 51 OD2 ? B ASP 99 ? B ASP 95 ? 1_555 ZN ? P ZN . ? B ZN 404 ? 1_555 NE2 ? B HIS 101 ? B HIS 97 ? 1_555 58.9 ? 52 OD1 ? B ASP 99 ? B ASP 95 ? 1_555 ZN ? P ZN . ? B ZN 404 ? 1_555 O ? S HOH . ? B HOH 505 ? 1_555 109.7 ? 53 OD2 ? B ASP 99 ? B ASP 95 ? 1_555 ZN ? P ZN . ? B ZN 404 ? 1_555 O ? S HOH . ? B HOH 505 ? 1_555 141.8 ? 54 NE2 ? B HIS 101 ? B HIS 97 ? 1_555 ZN ? P ZN . ? B ZN 404 ? 1_555 O ? S HOH . ? B HOH 505 ? 1_555 83.2 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2015-12-16 2 'Structure model' 1 1 2016-10-05 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Database references' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(phenix.refine: 1.8.4_1496)' 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS ? ? ? . 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? XSCALE ? ? ? . 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? . 4 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OE1 A GLU 9 ? ? OE1 A GLU 383 ? ? 1.75 2 1 OD1 A ASP 95 ? ? NE2 A HIS 97 ? ? 1.78 3 1 OD1 A ASP 111 ? ? OE2 B GLU 109 ? ? 1.88 4 1 OD2 B ASP 95 ? ? NE2 B HIS 97 ? ? 1.98 5 1 OE1 B GLU 109 ? ? OE1 B GLU 126 ? ? 2.09 6 1 OH B TYR 160 ? ? OD1 B ASP 177 ? ? 2.19 # _pdbx_validate_symm_contact.id 1 _pdbx_validate_symm_contact.PDB_model_num 1 _pdbx_validate_symm_contact.auth_atom_id_1 O _pdbx_validate_symm_contact.auth_asym_id_1 B _pdbx_validate_symm_contact.auth_comp_id_1 GLY _pdbx_validate_symm_contact.auth_seq_id_1 30 _pdbx_validate_symm_contact.PDB_ins_code_1 ? _pdbx_validate_symm_contact.label_alt_id_1 ? _pdbx_validate_symm_contact.site_symmetry_1 1_555 _pdbx_validate_symm_contact.auth_atom_id_2 OG _pdbx_validate_symm_contact.auth_asym_id_2 B _pdbx_validate_symm_contact.auth_comp_id_2 SER _pdbx_validate_symm_contact.auth_seq_id_2 230 _pdbx_validate_symm_contact.PDB_ins_code_2 ? _pdbx_validate_symm_contact.label_alt_id_2 ? _pdbx_validate_symm_contact.site_symmetry_2 2_545 _pdbx_validate_symm_contact.dist 2.13 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 LEU A 7 ? ? -101.58 -72.23 2 1 PRO A 10 ? ? -67.41 -176.17 3 1 HIS A 76 ? ? -92.34 -61.11 4 1 GLU A 172 ? ? 50.01 71.54 5 1 PRO A 208 ? ? -65.06 74.80 6 1 ARG A 267 ? ? -90.31 -63.43 7 1 SER A 272 ? ? 53.30 -115.99 8 1 ASP A 279 ? ? 60.71 70.07 9 1 LYS A 340 ? ? -121.38 -61.92 10 1 GLU A 361 ? ? -92.68 -61.62 11 1 ALA B 28 ? ? -131.87 -86.77 12 1 SER B 29 ? ? 167.63 178.39 13 1 PRO B 32 ? ? -67.58 -173.46 14 1 LEU B 52 ? ? -130.34 -63.80 15 1 ASP B 58 ? ? 85.11 -3.85 16 1 HIS B 76 ? ? -82.85 -73.97 17 1 GLN B 78 ? ? 179.92 165.33 18 1 PHE B 134 ? ? -129.83 -64.41 19 1 LYS B 159 ? ? -94.45 -64.87 20 1 THR B 191 ? ? -129.70 -60.46 21 1 VAL B 209 ? ? -126.11 -74.41 22 1 VAL B 263 ? ? 31.03 68.80 23 1 SER B 272 ? ? 55.16 -119.53 24 1 LYS B 278 ? ? -79.58 -164.66 25 1 PHE B 324 ? ? 67.76 78.88 26 1 LYS B 340 ? ? -86.20 -71.36 27 1 ASP B 378 ? ? -50.76 -73.09 28 1 GLU B 380 ? ? 169.56 171.31 # loop_ _pdbx_validate_peptide_omega.id _pdbx_validate_peptide_omega.PDB_model_num _pdbx_validate_peptide_omega.auth_comp_id_1 _pdbx_validate_peptide_omega.auth_asym_id_1 _pdbx_validate_peptide_omega.auth_seq_id_1 _pdbx_validate_peptide_omega.PDB_ins_code_1 _pdbx_validate_peptide_omega.label_alt_id_1 _pdbx_validate_peptide_omega.auth_comp_id_2 _pdbx_validate_peptide_omega.auth_asym_id_2 _pdbx_validate_peptide_omega.auth_seq_id_2 _pdbx_validate_peptide_omega.PDB_ins_code_2 _pdbx_validate_peptide_omega.label_alt_id_2 _pdbx_validate_peptide_omega.omega 1 1 VAL B 96 ? ? HIS B 97 ? ? -147.68 2 1 VAL B 262 ? ? VAL B 263 ? ? 128.86 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLY -3 ? A GLY 1 2 1 Y 1 A GLY -2 ? A GLY 2 3 1 Y 1 A ALA -1 ? A ALA 3 4 1 Y 1 A ASP 0 ? A ASP 4 5 1 Y 1 A GLY 392 ? A GLY 396 6 1 Y 1 B GLY -3 ? B GLY 1 7 1 Y 1 B GLY -2 ? B GLY 2 8 1 Y 1 B ALA -1 ? B ALA 3 9 1 Y 1 B ASP 0 ? B ASP 4 10 1 Y 1 B ALA 153 ? B ALA 157 11 1 Y 1 B ALA 154 ? B ALA 158 12 1 Y 1 B GLU 155 ? B GLU 159 13 1 Y 1 B THR 156 ? B THR 160 14 1 Y 1 B GLY 392 ? B GLY 396 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 BETA-D-MANNOSE BMA 4 ALPHA-D-MANNOSE MAN 5 'ZINC ION' ZN 6 water HOH #