data_4UTC # _entry.id 4UTC # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4UTC PDBE EBI-61244 WWPDB D_1290061244 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.content_type _pdbx_database_related.details PDB 4UTA unspecified ;CRYSTAL STRUCTURE OF DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN IN COMPLEX WITH THE FAB FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8 ; PDB 4UTB unspecified ;CRYSTAL STRUCTURE OF DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN IN COMPLEX WITH THE FAB FRAGMENT OF THE BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 ; # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 4UTC _pdbx_database_status.deposit_site PDBE _pdbx_database_status.process_site PDBE _pdbx_database_status.SG_entry . _pdbx_database_status.recvd_initial_deposition_date 2014-07-18 _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_sf ? _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Kikuti, C.' 1 'Rouvinski, A.' 2 'Guardado-Calvo, P.' 3 'Barba-Spaeth, G.' 4 'Duquerroy, S.' 5 'Vaney, M.C.' 6 'Rey, F.A.' 7 # loop_ _citation.id _citation.title _citation.journal_abbrev _citation.journal_volume _citation.page_first _citation.page_last _citation.year _citation.journal_id_ASTM _citation.country _citation.journal_id_ISSN _citation.journal_id_CSD _citation.book_publisher _citation.pdbx_database_id_PubMed _citation.pdbx_database_id_DOI primary 'Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.' Nature 520 109 ? 2015 NATUAS UK 0028-0836 0006 ? 25581790 10.1038/NATURE14130 1 'A New Class of Highly Potent, Broadly Neutralizing Antibodies Isolated from Viremic Patients Infected with Dengue Virus.' Nat.Immunol. 16 170 ? 2015 ? UK 1529-2908 ? ? 25501631 10.1038/NI.3058 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Rouvinski, A.' 1 primary 'Guardado-Calvo, P.' 2 primary 'Barba-Spaeth, G.' 3 primary 'Duquerroy, S.' 4 primary 'Vaney, M.' 5 primary 'Kikuti, C.M.' 6 primary 'Sanchez, M.E.N.' 7 primary 'Dejnirattisai, W.' 8 primary 'Wongwiwat, W.' 9 primary 'Haouz, A.' 10 primary 'Girard-Blanc, C.' 11 primary 'Petres, S.' 12 primary 'Shepard, W.E.' 13 primary 'Despres, P.' 14 primary 'Arenzana-Seisdedos, F.' 15 primary 'Dussart, P.' 16 primary 'Mongkolsapaya, J.' 17 primary 'Screaton, G.R.' 18 primary 'Rey, F.A.' 19 1 'Dejnirattisai, W.' 20 1 'Wongwiwat, W.' 21 1 'Supasa, S.' 22 1 'Zhang, X.' 23 1 'Dai, X.' 24 1 'Rouvinsky, A.' 25 1 'Jumnainsong, A.' 26 1 'Edwards, C.' 27 1 'Quyen, N.T.H.' 28 1 'Duangchinda, T.' 29 1 'Grimes, J.M.' 30 1 'Tsai, W.' 31 1 'Lai, C.' 32 1 'Wang, W.' 33 1 'Malasit, P.' 34 1 'Farrar, J.' 35 1 'Simmons, C.P.' 36 1 'Zhou, Z.H.' 37 1 'Rey, F.A.' 38 1 'Mongkolsapaya, J.' 39 1 'Screaton, G.R.' 40 # _cell.entry_id 4UTC _cell.length_a 105.462 _cell.length_b 105.462 _cell.length_c 165.895 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 16 _cell.pdbx_unique_axis ? # _symmetry.entry_id 4UTC _symmetry.space_group_name_H-M 'P 43 21 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 96 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'ENVELOPE GLYCOPROTEIN E' 46816.547 2 ? ? 'SOLUBLE ECTODOMAIN, RESIDUES 281-671' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 8 ? ? ? ? 3 non-polymer man ALPHA-L-FUCOSE 164.156 2 ? ? ? ? 4 non-polymer man BETA-D-MANNOSE 180.156 3 ? ? ? ? 5 water nat water 18.015 6 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'E PROTEIN' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;MRCIGISNRDFVEGVSGGSWVDIVLEHGSCVTTMAKNKPTLDFELIKTEAKQPATLRKYCIEAKLTNTTTESRCPTQGEP SLNEEQDKRFICKHSMVDRGWGNGCGLFGKGGIVTCAKFTCKKNMEGKIVQPENLEYTIVITPHSGEEHAVGNDTGKHGK EIKITPQSSTTEAELTGYGTVTMECSPRTGLDFNEMVLLQMEDKAWLVHRQWFLDLPLPWLPGADTQGSNWIQKETLVTF KNPHAKKQDVVVLGSQEGAMHTALTGATEIQMSSGNLLFTGHLKCRLRMDKLQLKGMSYSMCTGKFKIVKEIAETQHGTI VIRVQYEGDGSPCKIPFEITDLEKRHVLGRLITVNPIVTEKDSPVNIEAEPPFGDSYIIVGVEPGQLKLNWLRPLESRGP FEGKPIPNPLLGLDSTRTGHHH ; _entity_poly.pdbx_seq_one_letter_code_can ;MRCIGISNRDFVEGVSGGSWVDIVLEHGSCVTTMAKNKPTLDFELIKTEAKQPATLRKYCIEAKLTNTTTESRCPTQGEP SLNEEQDKRFICKHSMVDRGWGNGCGLFGKGGIVTCAKFTCKKNMEGKIVQPENLEYTIVITPHSGEEHAVGNDTGKHGK EIKITPQSSTTEAELTGYGTVTMECSPRTGLDFNEMVLLQMEDKAWLVHRQWFLDLPLPWLPGADTQGSNWIQKETLVTF KNPHAKKQDVVVLGSQEGAMHTALTGATEIQMSSGNLLFTGHLKCRLRMDKLQLKGMSYSMCTGKFKIVKEIAETQHGTI VIRVQYEGDGSPCKIPFEITDLEKRHVLGRLITVNPIVTEKDSPVNIEAEPPFGDSYIIVGVEPGQLKLNWLRPLESRGP FEGKPIPNPLLGLDSTRTGHHH ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 MET n 1 2 ARG n 1 3 CYS n 1 4 ILE n 1 5 GLY n 1 6 ILE n 1 7 SER n 1 8 ASN n 1 9 ARG n 1 10 ASP n 1 11 PHE n 1 12 VAL n 1 13 GLU n 1 14 GLY n 1 15 VAL n 1 16 SER n 1 17 GLY n 1 18 GLY n 1 19 SER n 1 20 TRP n 1 21 VAL n 1 22 ASP n 1 23 ILE n 1 24 VAL n 1 25 LEU n 1 26 GLU n 1 27 HIS n 1 28 GLY n 1 29 SER n 1 30 CYS n 1 31 VAL n 1 32 THR n 1 33 THR n 1 34 MET n 1 35 ALA n 1 36 LYS n 1 37 ASN n 1 38 LYS n 1 39 PRO n 1 40 THR n 1 41 LEU n 1 42 ASP n 1 43 PHE n 1 44 GLU n 1 45 LEU n 1 46 ILE n 1 47 LYS n 1 48 THR n 1 49 GLU n 1 50 ALA n 1 51 LYS n 1 52 GLN n 1 53 PRO n 1 54 ALA n 1 55 THR n 1 56 LEU n 1 57 ARG n 1 58 LYS n 1 59 TYR n 1 60 CYS n 1 61 ILE n 1 62 GLU n 1 63 ALA n 1 64 LYS n 1 65 LEU n 1 66 THR n 1 67 ASN n 1 68 THR n 1 69 THR n 1 70 THR n 1 71 GLU n 1 72 SER n 1 73 ARG n 1 74 CYS n 1 75 PRO n 1 76 THR n 1 77 GLN n 1 78 GLY n 1 79 GLU n 1 80 PRO n 1 81 SER n 1 82 LEU n 1 83 ASN n 1 84 GLU n 1 85 GLU n 1 86 GLN n 1 87 ASP n 1 88 LYS n 1 89 ARG n 1 90 PHE n 1 91 ILE n 1 92 CYS n 1 93 LYS n 1 94 HIS n 1 95 SER n 1 96 MET n 1 97 VAL n 1 98 ASP n 1 99 ARG n 1 100 GLY n 1 101 TRP n 1 102 GLY n 1 103 ASN n 1 104 GLY n 1 105 CYS n 1 106 GLY n 1 107 LEU n 1 108 PHE n 1 109 GLY n 1 110 LYS n 1 111 GLY n 1 112 GLY n 1 113 ILE n 1 114 VAL n 1 115 THR n 1 116 CYS n 1 117 ALA n 1 118 LYS n 1 119 PHE n 1 120 THR n 1 121 CYS n 1 122 LYS n 1 123 LYS n 1 124 ASN n 1 125 MET n 1 126 GLU n 1 127 GLY n 1 128 LYS n 1 129 ILE n 1 130 VAL n 1 131 GLN n 1 132 PRO n 1 133 GLU n 1 134 ASN n 1 135 LEU n 1 136 GLU n 1 137 TYR n 1 138 THR n 1 139 ILE n 1 140 VAL n 1 141 ILE n 1 142 THR n 1 143 PRO n 1 144 HIS n 1 145 SER n 1 146 GLY n 1 147 GLU n 1 148 GLU n 1 149 HIS n 1 150 ALA n 1 151 VAL n 1 152 GLY n 1 153 ASN n 1 154 ASP n 1 155 THR n 1 156 GLY n 1 157 LYS n 1 158 HIS n 1 159 GLY n 1 160 LYS n 1 161 GLU n 1 162 ILE n 1 163 LYS n 1 164 ILE n 1 165 THR n 1 166 PRO n 1 167 GLN n 1 168 SER n 1 169 SER n 1 170 THR n 1 171 THR n 1 172 GLU n 1 173 ALA n 1 174 GLU n 1 175 LEU n 1 176 THR n 1 177 GLY n 1 178 TYR n 1 179 GLY n 1 180 THR n 1 181 VAL n 1 182 THR n 1 183 MET n 1 184 GLU n 1 185 CYS n 1 186 SER n 1 187 PRO n 1 188 ARG n 1 189 THR n 1 190 GLY n 1 191 LEU n 1 192 ASP n 1 193 PHE n 1 194 ASN n 1 195 GLU n 1 196 MET n 1 197 VAL n 1 198 LEU n 1 199 LEU n 1 200 GLN n 1 201 MET n 1 202 GLU n 1 203 ASP n 1 204 LYS n 1 205 ALA n 1 206 TRP n 1 207 LEU n 1 208 VAL n 1 209 HIS n 1 210 ARG n 1 211 GLN n 1 212 TRP n 1 213 PHE n 1 214 LEU n 1 215 ASP n 1 216 LEU n 1 217 PRO n 1 218 LEU n 1 219 PRO n 1 220 TRP n 1 221 LEU n 1 222 PRO n 1 223 GLY n 1 224 ALA n 1 225 ASP n 1 226 THR n 1 227 GLN n 1 228 GLY n 1 229 SER n 1 230 ASN n 1 231 TRP n 1 232 ILE n 1 233 GLN n 1 234 LYS n 1 235 GLU n 1 236 THR n 1 237 LEU n 1 238 VAL n 1 239 THR n 1 240 PHE n 1 241 LYS n 1 242 ASN n 1 243 PRO n 1 244 HIS n 1 245 ALA n 1 246 LYS n 1 247 LYS n 1 248 GLN n 1 249 ASP n 1 250 VAL n 1 251 VAL n 1 252 VAL n 1 253 LEU n 1 254 GLY n 1 255 SER n 1 256 GLN n 1 257 GLU n 1 258 GLY n 1 259 ALA n 1 260 MET n 1 261 HIS n 1 262 THR n 1 263 ALA n 1 264 LEU n 1 265 THR n 1 266 GLY n 1 267 ALA n 1 268 THR n 1 269 GLU n 1 270 ILE n 1 271 GLN n 1 272 MET n 1 273 SER n 1 274 SER n 1 275 GLY n 1 276 ASN n 1 277 LEU n 1 278 LEU n 1 279 PHE n 1 280 THR n 1 281 GLY n 1 282 HIS n 1 283 LEU n 1 284 LYS n 1 285 CYS n 1 286 ARG n 1 287 LEU n 1 288 ARG n 1 289 MET n 1 290 ASP n 1 291 LYS n 1 292 LEU n 1 293 GLN n 1 294 LEU n 1 295 LYS n 1 296 GLY n 1 297 MET n 1 298 SER n 1 299 TYR n 1 300 SER n 1 301 MET n 1 302 CYS n 1 303 THR n 1 304 GLY n 1 305 LYS n 1 306 PHE n 1 307 LYS n 1 308 ILE n 1 309 VAL n 1 310 LYS n 1 311 GLU n 1 312 ILE n 1 313 ALA n 1 314 GLU n 1 315 THR n 1 316 GLN n 1 317 HIS n 1 318 GLY n 1 319 THR n 1 320 ILE n 1 321 VAL n 1 322 ILE n 1 323 ARG n 1 324 VAL n 1 325 GLN n 1 326 TYR n 1 327 GLU n 1 328 GLY n 1 329 ASP n 1 330 GLY n 1 331 SER n 1 332 PRO n 1 333 CYS n 1 334 LYS n 1 335 ILE n 1 336 PRO n 1 337 PHE n 1 338 GLU n 1 339 ILE n 1 340 THR n 1 341 ASP n 1 342 LEU n 1 343 GLU n 1 344 LYS n 1 345 ARG n 1 346 HIS n 1 347 VAL n 1 348 LEU n 1 349 GLY n 1 350 ARG n 1 351 LEU n 1 352 ILE n 1 353 THR n 1 354 VAL n 1 355 ASN n 1 356 PRO n 1 357 ILE n 1 358 VAL n 1 359 THR n 1 360 GLU n 1 361 LYS n 1 362 ASP n 1 363 SER n 1 364 PRO n 1 365 VAL n 1 366 ASN n 1 367 ILE n 1 368 GLU n 1 369 ALA n 1 370 GLU n 1 371 PRO n 1 372 PRO n 1 373 PHE n 1 374 GLY n 1 375 ASP n 1 376 SER n 1 377 TYR n 1 378 ILE n 1 379 ILE n 1 380 VAL n 1 381 GLY n 1 382 VAL n 1 383 GLU n 1 384 PRO n 1 385 GLY n 1 386 GLN n 1 387 LEU n 1 388 LYS n 1 389 LEU n 1 390 ASN n 1 391 TRP n 1 392 LEU n 1 393 ARG n 1 394 PRO n 1 395 LEU n 1 396 GLU n 1 397 SER n 1 398 ARG n 1 399 GLY n 1 400 PRO n 1 401 PHE n 1 402 GLU n 1 403 GLY n 1 404 LYS n 1 405 PRO n 1 406 ILE n 1 407 PRO n 1 408 ASN n 1 409 PRO n 1 410 LEU n 1 411 LEU n 1 412 GLY n 1 413 LEU n 1 414 ASP n 1 415 SER n 1 416 THR n 1 417 ARG n 1 418 THR n 1 419 GLY n 1 420 HIS n 1 421 HIS n 1 422 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name ? _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene ? _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain FGA-02 _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'DENGUE VIRUS 2' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 11060 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'FRUIT FLY' _entity_src_gen.pdbx_host_org_scientific_name 'DROSOPHILA MELANOGASTER' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7227 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line 'SCHNEIDER 2' _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name PMT/BIP/V5-HIS _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code Q68Y26_9FLAV _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ? _struct_ref.pdbx_align_begin ? _struct_ref.pdbx_db_accession Q68Y26 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4UTC A 1 ? 391 ? Q68Y26 281 ? 671 ? 1 391 2 1 4UTC B 1 ? 391 ? Q68Y26 281 ? 671 ? 1 391 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 4UTC LEU A 392 ? UNP Q68Y26 ? ? 'expression tag' 392 1 1 4UTC ARG A 393 ? UNP Q68Y26 ? ? 'expression tag' 393 2 1 4UTC PRO A 394 ? UNP Q68Y26 ? ? 'expression tag' 394 3 1 4UTC LEU A 395 ? UNP Q68Y26 ? ? 'expression tag' 395 4 1 4UTC GLU A 396 ? UNP Q68Y26 ? ? 'expression tag' 396 5 1 4UTC SER A 397 ? UNP Q68Y26 ? ? 'expression tag' 397 6 1 4UTC ARG A 398 ? UNP Q68Y26 ? ? 'expression tag' 398 7 1 4UTC GLY A 399 ? UNP Q68Y26 ? ? 'expression tag' 399 8 1 4UTC PRO A 400 ? UNP Q68Y26 ? ? 'expression tag' 400 9 1 4UTC PHE A 401 ? UNP Q68Y26 ? ? 'expression tag' 401 10 1 4UTC GLU A 402 ? UNP Q68Y26 ? ? 'expression tag' 402 11 1 4UTC GLY A 403 ? UNP Q68Y26 ? ? 'expression tag' 403 12 1 4UTC LYS A 404 ? UNP Q68Y26 ? ? 'expression tag' 404 13 1 4UTC PRO A 405 ? UNP Q68Y26 ? ? 'expression tag' 405 14 1 4UTC ILE A 406 ? UNP Q68Y26 ? ? 'expression tag' 406 15 1 4UTC PRO A 407 ? UNP Q68Y26 ? ? 'expression tag' 407 16 1 4UTC ASN A 408 ? UNP Q68Y26 ? ? 'expression tag' 408 17 1 4UTC PRO A 409 ? UNP Q68Y26 ? ? 'expression tag' 409 18 1 4UTC LEU A 410 ? UNP Q68Y26 ? ? 'expression tag' 410 19 1 4UTC LEU A 411 ? UNP Q68Y26 ? ? 'expression tag' 411 20 1 4UTC GLY A 412 ? UNP Q68Y26 ? ? 'expression tag' 412 21 1 4UTC LEU A 413 ? UNP Q68Y26 ? ? 'expression tag' 413 22 1 4UTC ASP A 414 ? UNP Q68Y26 ? ? 'expression tag' 414 23 1 4UTC SER A 415 ? UNP Q68Y26 ? ? 'expression tag' 415 24 1 4UTC THR A 416 ? UNP Q68Y26 ? ? 'expression tag' 416 25 1 4UTC ARG A 417 ? UNP Q68Y26 ? ? 'expression tag' 417 26 1 4UTC THR A 418 ? UNP Q68Y26 ? ? 'expression tag' 418 27 1 4UTC GLY A 419 ? UNP Q68Y26 ? ? 'expression tag' 419 28 1 4UTC HIS A 420 ? UNP Q68Y26 ? ? 'expression tag' 420 29 1 4UTC HIS A 421 ? UNP Q68Y26 ? ? 'expression tag' 421 30 1 4UTC HIS A 422 ? UNP Q68Y26 ? ? 'expression tag' 422 31 1 4UTC LYS A 118 ? UNP Q68Y26 MET 398 conflict 118 32 2 4UTC LEU B 392 ? UNP Q68Y26 ? ? 'expression tag' 392 33 2 4UTC ARG B 393 ? UNP Q68Y26 ? ? 'expression tag' 393 34 2 4UTC PRO B 394 ? UNP Q68Y26 ? ? 'expression tag' 394 35 2 4UTC LEU B 395 ? UNP Q68Y26 ? ? 'expression tag' 395 36 2 4UTC GLU B 396 ? UNP Q68Y26 ? ? 'expression tag' 396 37 2 4UTC SER B 397 ? UNP Q68Y26 ? ? 'expression tag' 397 38 2 4UTC ARG B 398 ? UNP Q68Y26 ? ? 'expression tag' 398 39 2 4UTC GLY B 399 ? UNP Q68Y26 ? ? 'expression tag' 399 40 2 4UTC PRO B 400 ? UNP Q68Y26 ? ? 'expression tag' 400 41 2 4UTC PHE B 401 ? UNP Q68Y26 ? ? 'expression tag' 401 42 2 4UTC GLU B 402 ? UNP Q68Y26 ? ? 'expression tag' 402 43 2 4UTC GLY B 403 ? UNP Q68Y26 ? ? 'expression tag' 403 44 2 4UTC LYS B 404 ? UNP Q68Y26 ? ? 'expression tag' 404 45 2 4UTC PRO B 405 ? UNP Q68Y26 ? ? 'expression tag' 405 46 2 4UTC ILE B 406 ? UNP Q68Y26 ? ? 'expression tag' 406 47 2 4UTC PRO B 407 ? UNP Q68Y26 ? ? 'expression tag' 407 48 2 4UTC ASN B 408 ? UNP Q68Y26 ? ? 'expression tag' 408 49 2 4UTC PRO B 409 ? UNP Q68Y26 ? ? 'expression tag' 409 50 2 4UTC LEU B 410 ? UNP Q68Y26 ? ? 'expression tag' 410 51 2 4UTC LEU B 411 ? UNP Q68Y26 ? ? 'expression tag' 411 52 2 4UTC GLY B 412 ? UNP Q68Y26 ? ? 'expression tag' 412 53 2 4UTC LEU B 413 ? UNP Q68Y26 ? ? 'expression tag' 413 54 2 4UTC ASP B 414 ? UNP Q68Y26 ? ? 'expression tag' 414 55 2 4UTC SER B 415 ? UNP Q68Y26 ? ? 'expression tag' 415 56 2 4UTC THR B 416 ? UNP Q68Y26 ? ? 'expression tag' 416 57 2 4UTC ARG B 417 ? UNP Q68Y26 ? ? 'expression tag' 417 58 2 4UTC THR B 418 ? UNP Q68Y26 ? ? 'expression tag' 418 59 2 4UTC GLY B 419 ? UNP Q68Y26 ? ? 'expression tag' 419 60 2 4UTC HIS B 420 ? UNP Q68Y26 ? ? 'expression tag' 420 61 2 4UTC HIS B 421 ? UNP Q68Y26 ? ? 'expression tag' 421 62 2 4UTC HIS B 422 ? UNP Q68Y26 ? ? 'expression tag' 422 63 2 4UTC LYS B 118 ? UNP Q68Y26 MET 398 conflict 118 64 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FUC saccharide . ALPHA-L-FUCOSE ? 'C6 H12 O5' 164.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 4UTC _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.45 _exptl_crystal.density_percent_sol 49.8 _exptl_crystal.description NONE # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method ? _exptl_crystal_grow.temp ? _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details '100MM TRIS PH 8.0 86 MM NAFORMATE 16% PEG 3,350' # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'MARMOSAIC 225 mm CCD' _diffrn_detector.pdbx_collection_date 2008-09-27 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.872600 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'ESRF BEAMLINE ID23-2' _diffrn_source.pdbx_synchrotron_site ESRF _diffrn_source.pdbx_synchrotron_beamline ID23-2 _diffrn_source.pdbx_wavelength 0.872600 _diffrn_source.pdbx_wavelength_list ? # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 4UTC _reflns.observed_criterion_sigma_I 0.0 _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 50.00 _reflns.d_resolution_high 3.10 _reflns.number_obs 17615 _reflns.number_all ? _reflns.percent_possible_obs 99.3 _reflns.pdbx_Rmerge_I_obs 0.10 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 23.90 _reflns.B_iso_Wilson_estimate 95.31 _reflns.pdbx_redundancy 17.1 # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 3.10 _reflns_shell.d_res_low 3.26 _reflns_shell.percent_possible_all 96.0 _reflns_shell.Rmerge_I_obs 0.61 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 2.50 _reflns_shell.pdbx_redundancy 6.5 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 4UTC _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 17453 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.0 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 20.00 _refine.ls_d_res_high 3.08 _refine.ls_percent_reflns_obs 97.54 _refine.ls_R_factor_obs 0.2140 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.2106 _refine.ls_R_factor_R_free 0.2788 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.05 _refine.ls_number_reflns_R_free 882 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.9254 _refine.correlation_coeff_Fo_to_Fc_free 0.8736 _refine.B_iso_mean 85.62 _refine.aniso_B[1][1] 0.7469 _refine.aniso_B[2][2] 0.7469 _refine.aniso_B[3][3] -1.4938 _refine.aniso_B[1][2] 0.0000 _refine.aniso_B[1][3] 0.0000 _refine.aniso_B[2][3] 0.0000 _refine.solvent_model_details ? _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'IDEAL-DIST CONTACT TERM CONTACT SETUP. ALL ATOMS HAVE CCP4 ATOM TYPE FROM LIBRARY' _refine.pdbx_starting_model 'PDB ENTRY 1OAN' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.pdbx_overall_phase_error ? _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI 0.512 # _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_analyze.entry_id 4UTC _refine_analyze.Luzzati_coordinate_error_obs 0.585 _refine_analyze.Luzzati_sigma_a_obs ? _refine_analyze.Luzzati_d_res_low_obs ? _refine_analyze.Luzzati_coordinate_error_free ? _refine_analyze.Luzzati_sigma_a_free ? _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6072 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 165 _refine_hist.number_atoms_solvent 6 _refine_hist.number_atoms_total 6243 _refine_hist.d_res_high 3.08 _refine_hist.d_res_low 20.00 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function t_bond_d 0.010 ? 2.00 6383 'X-RAY DIFFRACTION' HARMONIC t_angle_deg 1.33 ? 2.00 8659 'X-RAY DIFFRACTION' HARMONIC t_dihedral_angle_d ? ? 2.00 2295 'X-RAY DIFFRACTION' SINUSOIDAL t_incorr_chiral_ct ? ? ? ? 'X-RAY DIFFRACTION' ? t_pseud_angle ? ? ? ? 'X-RAY DIFFRACTION' ? t_trig_c_planes ? ? 2.00 158 'X-RAY DIFFRACTION' HARMONIC t_gen_planes ? ? 5.00 891 'X-RAY DIFFRACTION' HARMONIC t_it ? ? 20.00 6383 'X-RAY DIFFRACTION' HARMONIC t_nbd ? ? ? ? 'X-RAY DIFFRACTION' ? t_omega_torsion 2.70 ? ? ? 'X-RAY DIFFRACTION' ? t_other_torsion 22.12 ? ? ? 'X-RAY DIFFRACTION' ? t_improper_torsion ? ? ? ? 'X-RAY DIFFRACTION' ? t_chiral_improper_torsion ? ? 5.00 895 'X-RAY DIFFRACTION' SEMIHARMONIC t_sum_occupancies ? ? ? ? 'X-RAY DIFFRACTION' ? t_utility_distance ? ? ? ? 'X-RAY DIFFRACTION' ? t_utility_angle ? ? ? ? 'X-RAY DIFFRACTION' ? t_utility_torsion ? ? ? ? 'X-RAY DIFFRACTION' ? t_ideal_dist_contact ? ? 4.00 6819 'X-RAY DIFFRACTION' SEMIHARMONIC # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 9 _refine_ls_shell.d_res_high 3.08 _refine_ls_shell.d_res_low 3.27 _refine_ls_shell.number_reflns_R_work 2275 _refine_ls_shell.R_factor_R_work 0.2540 _refine_ls_shell.percent_reflns_obs 97.54 _refine_ls_shell.R_factor_R_free 0.3370 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free 5.41 _refine_ls_shell.number_reflns_R_free 130 _refine_ls_shell.number_reflns_all 2405 _refine_ls_shell.R_factor_all 0.2588 # _struct_ncs_oper.id 1 _struct_ncs_oper.code given _struct_ncs_oper.details ? _struct_ncs_oper.matrix[1][1] -0.172000 _struct_ncs_oper.matrix[1][2] 0.890000 _struct_ncs_oper.matrix[1][3] -0.422000 _struct_ncs_oper.matrix[2][1] 0.897000 _struct_ncs_oper.matrix[2][2] -0.035000 _struct_ncs_oper.matrix[2][3] -0.440000 _struct_ncs_oper.matrix[3][1] -0.406000 _struct_ncs_oper.matrix[3][2] -0.454000 _struct_ncs_oper.matrix[3][3] -0.793000 _struct_ncs_oper.vector[1] -0.57200 _struct_ncs_oper.vector[2] -37.68400 _struct_ncs_oper.vector[3] -83.16500 # _struct.entry_id 4UTC _struct.title 'Crystal structure of dengue 2 virus envelope glycoprotein' _struct.pdbx_descriptor 'ENVELOPE GLYCOPROTEIN E' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 4UTC _struct_keywords.pdbx_keywords 'VIRAL PROTEIN' _struct_keywords.text 'VIRAL PROTEIN, MEMBRANE FUSION, CLASS 2 FUSION PROTEIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 3 ? E N N 2 ? F N N 2 ? G N N 2 ? H N N 2 ? I N N 3 ? J N N 2 ? K N N 4 ? L N N 4 ? M N N 4 ? N N N 2 ? O N N 2 ? P N N 5 ? Q N N 5 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 LEU A 82 ? GLN A 86 ? LEU A 82 GLN A 86 5 ? 5 HELX_P HELX_P2 2 GLY A 100 ? GLY A 104 ? GLY A 100 GLY A 104 5 ? 5 HELX_P HELX_P3 3 GLN A 131 ? GLU A 133 ? GLN A 131 GLU A 133 5 ? 3 HELX_P HELX_P4 4 ARG A 210 ? ASP A 215 ? ARG A 210 ASP A 215 1 ? 6 HELX_P HELX_P5 5 GLN A 233 ? THR A 236 ? GLN A 233 THR A 236 5 ? 4 HELX_P HELX_P6 6 GLN A 256 ? LEU A 264 ? GLN A 256 LEU A 264 1 ? 9 HELX_P HELX_P7 7 LEU B 82 ? ASP B 87 ? LEU B 82 ASP B 87 5 ? 6 HELX_P HELX_P8 8 GLN B 131 ? GLU B 133 ? GLN B 131 GLU B 133 5 ? 3 HELX_P HELX_P9 9 ARG B 210 ? ASP B 215 ? ARG B 210 ASP B 215 1 ? 6 HELX_P HELX_P10 10 GLN B 233 ? THR B 236 ? GLN B 233 THR B 236 5 ? 4 HELX_P HELX_P11 11 GLN B 256 ? LEU B 264 ? GLN B 256 LEU B 264 1 ? 9 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 3 SG ? ? ? 1_555 A CYS 30 SG ? ? A CYS 3 A CYS 30 1_555 ? ? ? ? ? ? ? 2.040 ? disulf2 disulf ? ? A CYS 60 SG ? ? ? 1_555 A CYS 121 SG ? ? A CYS 60 A CYS 121 1_555 ? ? ? ? ? ? ? 2.070 ? disulf3 disulf ? ? A CYS 74 SG ? ? ? 1_555 A CYS 105 SG ? ? A CYS 74 A CYS 105 1_555 ? ? ? ? ? ? ? 2.042 ? disulf4 disulf ? ? A CYS 92 SG ? ? ? 1_555 A CYS 116 SG ? ? A CYS 92 A CYS 116 1_555 ? ? ? ? ? ? ? 2.042 ? disulf5 disulf ? ? A CYS 185 SG ? ? ? 1_555 A CYS 285 SG ? ? A CYS 185 A CYS 285 1_555 ? ? ? ? ? ? ? 2.038 ? disulf6 disulf ? ? A CYS 302 SG ? ? ? 1_555 A CYS 333 SG ? ? A CYS 302 A CYS 333 1_555 ? ? ? ? ? ? ? 2.060 ? disulf7 disulf ? ? B CYS 3 SG ? ? ? 1_555 B CYS 30 SG ? ? B CYS 3 B CYS 30 1_555 ? ? ? ? ? ? ? 2.039 ? disulf8 disulf ? ? B CYS 60 SG ? ? ? 1_555 B CYS 121 SG ? ? B CYS 60 B CYS 121 1_555 ? ? ? ? ? ? ? 2.061 ? disulf9 disulf ? ? B CYS 74 SG ? ? ? 1_555 B CYS 105 SG ? ? B CYS 74 B CYS 105 1_555 ? ? ? ? ? ? ? 2.020 ? disulf10 disulf ? ? B CYS 92 SG ? ? ? 1_555 B CYS 116 SG ? ? B CYS 92 B CYS 116 1_555 ? ? ? ? ? ? ? 2.034 ? disulf11 disulf ? ? B CYS 185 SG ? ? ? 1_555 B CYS 285 SG ? ? B CYS 185 B CYS 285 1_555 ? ? ? ? ? ? ? 2.037 ? disulf12 disulf ? ? B CYS 302 SG ? ? ? 1_555 B CYS 333 SG ? ? B CYS 302 B CYS 333 1_555 ? ? ? ? ? ? ? 2.049 ? covale1 covale ? ? A ASN 67 ND2 ? ? ? 1_555 F NAG . C1 ? ? A ASN 67 A NAG 567 1_555 ? ? ? ? ? ? ? 1.434 ? covale2 covale ? ? A ASN 153 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 153 A NAG 501 1_555 ? ? ? ? ? ? ? 1.437 ? covale3 covale ? ? C NAG . O6 ? ? ? 1_555 D FUC . C1 ? ? A NAG 501 A FUC 502 1_555 ? ? ? ? ? ? ? 1.406 ? covale4 covale ? ? C NAG . O4 ? ? ? 1_555 E NAG . C1 ? ? A NAG 501 A NAG 503 1_555 ? ? ? ? ? ? ? 1.419 ? covale5 covale ? ? F NAG . O4 ? ? ? 1_555 G NAG . C1 ? ? A NAG 567 A NAG 569 1_555 ? ? ? ? ? ? ? 1.434 ? covale6 covale ? ? B ASN 67 ND2 ? ? ? 1_555 N NAG . C1 ? ? B ASN 67 B NAG 567 1_555 ? ? ? ? ? ? ? 1.431 ? covale7 covale ? ? B ASN 153 ND2 ? ? ? 1_555 H NAG . C1 ? ? B ASN 153 B NAG 501 1_555 ? ? ? ? ? ? ? 1.438 ? covale8 covale ? ? H NAG . O4 ? ? ? 1_555 J NAG . C1 ? ? B NAG 501 B NAG 503 1_555 ? ? ? ? ? ? ? 1.412 ? covale9 covale ? ? H NAG . O6 ? ? ? 1_555 I FUC . C1 ? ? B NAG 501 B FUC 502 1_555 ? ? ? ? ? ? ? 1.407 ? covale10 covale ? ? J NAG . O4 ? ? ? 1_555 K BMA . C1 ? ? B NAG 503 B BMA 504 1_555 ? ? ? ? ? ? ? 1.466 ? covale11 covale ? ? K BMA . O6 ? ? ? 1_555 L BMA . C1 ? ? B BMA 504 B BMA 505 1_555 ? ? ? ? ? ? ? 1.401 ? covale12 covale ? ? K BMA . O3 ? ? ? 1_555 M BMA . C1 ? ? B BMA 504 B BMA 506 1_555 ? ? ? ? ? ? ? 1.516 ? covale13 covale ? ? N NAG . O4 ? ? ? 1_555 O NAG . C1 ? ? B NAG 567 B NAG 569 1_555 ? ? ? ? ? ? ? 1.428 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 SER 331 A . ? SER 331 A PRO 332 A ? PRO 332 A 1 3.49 2 GLU 383 A . ? GLU 383 A PRO 384 A ? PRO 384 A 1 0.14 3 SER 331 B . ? SER 331 B PRO 332 B ? PRO 332 B 1 2.94 4 GLU 383 B . ? GLU 383 B PRO 384 B ? PRO 384 B 1 4.71 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA ? 5 ? AB ? 4 ? AC ? 2 ? AD ? 7 ? AE ? 4 ? AF ? 2 ? AG ? 4 ? AH ? 2 ? AI ? 3 ? BA ? 5 ? BB ? 4 ? BC ? 4 ? BD ? 3 ? BE ? 2 ? BF ? 4 ? BG ? 2 ? BH ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA 1 2 ? parallel AA 2 3 ? anti-parallel AA 3 4 ? anti-parallel AA 4 5 ? anti-parallel AB 1 2 ? anti-parallel AB 2 3 ? anti-parallel AB 3 4 ? anti-parallel AC 1 2 ? anti-parallel AD 1 2 ? anti-parallel AD 2 3 ? parallel AD 3 4 ? anti-parallel AD 4 5 ? anti-parallel AD 5 6 ? anti-parallel AD 6 7 ? anti-parallel AE 1 2 ? anti-parallel AE 2 3 ? parallel AE 3 4 ? anti-parallel AF 1 2 ? anti-parallel AG 1 2 ? anti-parallel AG 2 3 ? anti-parallel AG 3 4 ? anti-parallel AH 1 2 ? anti-parallel AI 1 2 ? anti-parallel AI 2 3 ? anti-parallel BA 1 2 ? parallel BA 2 3 ? anti-parallel BA 3 4 ? anti-parallel BA 4 5 ? anti-parallel BB 1 2 ? anti-parallel BB 2 3 ? anti-parallel BB 3 4 ? anti-parallel BC 1 2 ? anti-parallel BC 2 3 ? anti-parallel BC 3 4 ? anti-parallel BD 1 2 ? anti-parallel BD 2 3 ? anti-parallel BE 1 2 ? anti-parallel BF 1 2 ? anti-parallel BF 2 3 ? anti-parallel BF 3 4 ? anti-parallel BG 1 2 ? anti-parallel BH 1 2 ? anti-parallel BH 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA 1 ARG A 9 ? GLU A 13 ? ARG A 9 GLU A 13 AA 2 CYS A 30 ? ALA A 35 ? CYS A 30 ALA A 35 AA 3 LYS A 38 ? ALA A 50 ? LYS A 38 ALA A 50 AA 4 LEU A 135 ? PRO A 143 ? LEU A 135 PRO A 143 AA 5 LYS A 160 ? ILE A 164 ? LYS A 160 ILE A 164 AB 1 TRP A 20 ? LEU A 25 ? TRP A 20 LEU A 25 AB 2 LEU A 283 ? ARG A 288 ? LEU A 283 ARG A 288 AB 3 GLY A 179 ? SER A 186 ? GLY A 179 SER A 186 AB 4 THR A 170 ? LEU A 175 ? THR A 170 LEU A 175 AC 1 PHE A 90 ? ARG A 99 ? PHE A 90 ARG A 99 AC 2 GLY A 109 ? ILE A 129 ? GLY A 109 ILE A 129 AD 1 TRP A 220 ? PRO A 222 ? TRP A 220 PRO A 222 AD 2 ALA A 54 ? SER A 72 ? ALA A 54 SER A 72 AD 3 GLY A 109 ? ILE A 129 ? GLY A 109 ILE A 129 AD 4 MET A 196 ? GLN A 200 ? MET A 196 GLN A 200 AD 5 LYS A 204 ? HIS A 209 ? LYS A 204 HIS A 209 AD 6 THR A 268 ? SER A 273 ? THR A 268 SER A 273 AD 7 ASN A 276 ? LEU A 277 ? ASN A 276 LEU A 277 AE 1 TRP A 220 ? PRO A 222 ? TRP A 220 PRO A 222 AE 2 ALA A 54 ? SER A 72 ? ALA A 54 SER A 72 AE 3 GLY A 109 ? ILE A 129 ? GLY A 109 ILE A 129 AE 4 PHE A 90 ? ARG A 99 ? PHE A 90 ARG A 99 AF 1 VAL A 238 ? LYS A 241 ? VAL A 238 LYS A 241 AF 2 ASP A 249 ? VAL A 252 ? ASP A 249 VAL A 252 AG 1 PHE A 306 ? GLU A 314 ? PHE A 306 GLU A 314 AG 2 ILE A 320 ? TYR A 326 ? ILE A 320 TYR A 326 AG 3 VAL A 365 ? GLU A 370 ? VAL A 365 GLU A 370 AG 4 ARG A 350 ? LEU A 351 ? ARG A 350 LEU A 351 AH 1 CYS A 333 ? LYS A 334 ? CYS A 333 LYS A 334 AH 2 ILE A 357 ? VAL A 358 ? ILE A 357 VAL A 358 AI 1 PHE A 337 ? THR A 340 ? PHE A 337 THR A 340 AI 2 GLY A 374 ? VAL A 380 ? GLY A 374 VAL A 380 AI 3 LEU A 387 ? ARG A 393 ? LEU A 387 ARG A 393 BA 1 ARG B 9 ? GLU B 13 ? ARG B 9 GLU B 13 BA 2 CYS B 30 ? ALA B 35 ? CYS B 30 ALA B 35 BA 3 LYS B 38 ? ALA B 50 ? LYS B 38 ALA B 50 BA 4 LEU B 135 ? PRO B 143 ? LEU B 135 PRO B 143 BA 5 LYS B 160 ? ILE B 164 ? LYS B 160 ILE B 164 BB 1 VAL B 21 ? LEU B 25 ? VAL B 21 LEU B 25 BB 2 HIS B 282 ? ARG B 288 ? HIS B 282 ARG B 288 BB 3 GLY B 179 ? ARG B 188 ? GLY B 179 ARG B 188 BB 4 THR B 170 ? LEU B 175 ? THR B 170 LEU B 175 BC 1 PHE B 90 ? ARG B 99 ? PHE B 90 ARG B 99 BC 2 GLY B 109 ? ILE B 129 ? GLY B 109 ILE B 129 BC 3 ALA B 54 ? SER B 72 ? ALA B 54 SER B 72 BC 4 TRP B 220 ? PRO B 222 ? TRP B 220 PRO B 222 BD 1 MET B 196 ? GLN B 200 ? MET B 196 GLN B 200 BD 2 ALA B 205 ? HIS B 209 ? ALA B 205 HIS B 209 BD 3 THR B 268 ? ILE B 270 ? THR B 268 ILE B 270 BE 1 VAL B 238 ? LYS B 241 ? VAL B 238 LYS B 241 BE 2 ASP B 249 ? VAL B 252 ? ASP B 249 VAL B 252 BF 1 PHE B 306 ? GLU B 314 ? PHE B 306 GLU B 314 BF 2 ILE B 320 ? TYR B 326 ? ILE B 320 TYR B 326 BF 3 VAL B 365 ? GLU B 370 ? VAL B 365 GLU B 370 BF 4 ARG B 350 ? LEU B 351 ? ARG B 350 LEU B 351 BG 1 CYS B 333 ? LYS B 334 ? CYS B 333 LYS B 334 BG 2 ILE B 357 ? VAL B 358 ? ILE B 357 VAL B 358 BH 1 PHE B 337 ? THR B 340 ? PHE B 337 THR B 340 BH 2 GLY B 374 ? VAL B 380 ? GLY B 374 VAL B 380 BH 3 LEU B 387 ? ARG B 393 ? LEU B 387 ARG B 393 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA 1 2 N ASP A 10 ? N ASP A 10 O CYS A 30 ? O CYS A 30 AA 2 3 N ALA A 35 ? N ALA A 35 O LYS A 38 ? O LYS A 38 AA 3 4 N GLU A 49 ? N GLU A 49 O GLU A 136 ? O GLU A 136 AA 4 5 N ILE A 141 ? N ILE A 141 O LYS A 160 ? O LYS A 160 AB 1 2 N LEU A 25 ? N LEU A 25 O LEU A 283 ? O LEU A 283 AB 2 3 N ARG A 288 ? N ARG A 288 O THR A 182 ? O THR A 182 AB 3 4 N MET A 183 ? N MET A 183 O THR A 171 ? O THR A 171 AC 1 2 N ARG A 99 ? N ARG A 99 O GLY A 109 ? O GLY A 109 AD 1 2 N LEU A 221 ? N LEU A 221 O LYS A 58 ? O LYS A 58 AD 2 3 N GLU A 71 ? N GLU A 71 O VAL A 114 ? O VAL A 114 AD 3 4 N LYS A 128 ? N LYS A 128 O LEU A 198 ? O LEU A 198 AD 4 5 N LEU A 199 ? N LEU A 199 O TRP A 206 ? O TRP A 206 AD 5 6 N LEU A 207 ? N LEU A 207 O THR A 268 ? O THR A 268 AD 6 7 N SER A 273 ? N SER A 273 O ASN A 276 ? O ASN A 276 AE 1 2 N LEU A 221 ? N LEU A 221 O LYS A 58 ? O LYS A 58 AE 2 3 N GLU A 71 ? N GLU A 71 O VAL A 114 ? O VAL A 114 AE 3 4 N ALA A 117 ? N ALA A 117 O ILE A 91 ? O ILE A 91 AF 1 2 N LYS A 241 ? N LYS A 241 O ASP A 249 ? O ASP A 249 AG 1 2 N ALA A 313 ? N ALA A 313 O VAL A 321 ? O VAL A 321 AG 2 3 N VAL A 324 ? N VAL A 324 O VAL A 365 ? O VAL A 365 AG 3 4 N GLU A 370 ? N GLU A 370 O ARG A 350 ? O ARG A 350 AH 1 2 N CYS A 333 ? N CYS A 333 O VAL A 358 ? O VAL A 358 AI 1 2 N THR A 340 ? N THR A 340 O TYR A 377 ? O TYR A 377 AI 2 3 N VAL A 380 ? N VAL A 380 O LEU A 387 ? O LEU A 387 BA 1 2 N ASP B 10 ? N ASP B 10 O CYS B 30 ? O CYS B 30 BA 2 3 N ALA B 35 ? N ALA B 35 O LYS B 38 ? O LYS B 38 BA 3 4 N GLU B 49 ? N GLU B 49 O GLU B 136 ? O GLU B 136 BA 4 5 N ILE B 141 ? N ILE B 141 O LYS B 160 ? O LYS B 160 BB 1 2 N LEU B 25 ? N LEU B 25 O LEU B 283 ? O LEU B 283 BB 2 3 N ARG B 288 ? N ARG B 288 O THR B 182 ? O THR B 182 BB 3 4 N MET B 183 ? N MET B 183 O THR B 171 ? O THR B 171 BC 1 2 N ARG B 99 ? N ARG B 99 O GLY B 109 ? O GLY B 109 BC 2 3 N ILE B 129 ? N ILE B 129 O ALA B 54 ? O ALA B 54 BC 3 4 N LYS B 58 ? N LYS B 58 O LEU B 221 ? O LEU B 221 BD 1 2 N LEU B 199 ? N LEU B 199 O TRP B 206 ? O TRP B 206 BD 2 3 N LEU B 207 ? N LEU B 207 O THR B 268 ? O THR B 268 BE 1 2 N LYS B 241 ? N LYS B 241 O ASP B 249 ? O ASP B 249 BF 1 2 N ALA B 313 ? N ALA B 313 O VAL B 321 ? O VAL B 321 BF 2 3 N VAL B 324 ? N VAL B 324 O VAL B 365 ? O VAL B 365 BF 3 4 N GLU B 370 ? N GLU B 370 O ARG B 350 ? O ARG B 350 BG 1 2 N CYS B 333 ? N CYS B 333 O VAL B 358 ? O VAL B 358 BH 1 2 O THR B 340 ? O THR B 340 N TYR B 377 ? N TYR B 377 BH 2 3 N VAL B 380 ? N VAL B 380 O LEU B 387 ? O LEU B 387 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 3 'Binding site for Poly-Saccharide residues NAG A 567 through NAG A 569 bound to ASN A 67' AC2 Software ? ? ? ? 6 'Binding site for Poly-Saccharide residues NAG A 501 through NAG A 503 bound to ASN A 153' AC3 Software ? ? ? ? 2 'Binding site for Poly-Saccharide residues NAG B 567 through NAG B 569 bound to ASN B 67' AC4 Software ? ? ? ? 11 'Binding site for Poly-Saccharide residues NAG B 501 through BMA B 506 bound to ASN B 153' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 3 ASN A 67 ? ASN A 67 . ? 1_555 ? 2 AC1 3 ARG A 89 ? ARG A 89 . ? 1_555 ? 3 AC1 3 LYS A 118 ? LYS A 118 . ? 1_555 ? 4 AC2 6 GLU A 147 ? GLU A 147 . ? 1_555 ? 5 AC2 6 HIS A 149 ? HIS A 149 . ? 1_555 ? 6 AC2 6 ASN A 153 ? ASN A 153 . ? 1_555 ? 7 AC2 6 LYS A 157 ? LYS A 157 . ? 1_555 ? 8 AC2 6 HIS A 158 ? HIS A 158 . ? 1_555 ? 9 AC2 6 GLY B 102 ? GLY B 102 . ? 1_555 ? 10 AC3 2 ASN B 67 ? ASN B 67 . ? 1_555 ? 11 AC3 2 LYS B 118 ? LYS B 118 . ? 1_555 ? 12 AC4 11 GLN A 77 ? GLN A 77 . ? 8_554 ? 13 AC4 11 GLY A 102 ? GLY A 102 . ? 1_555 ? 14 AC4 11 LYS B 88 ? LYS B 88 . ? 6_544 ? 15 AC4 11 GLU B 147 ? GLU B 147 . ? 1_555 ? 16 AC4 11 HIS B 149 ? HIS B 149 . ? 1_555 ? 17 AC4 11 ASN B 153 ? ASN B 153 . ? 1_555 ? 18 AC4 11 LYS B 157 ? LYS B 157 . ? 1_555 ? 19 AC4 11 HIS B 158 ? HIS B 158 . ? 1_555 ? 20 AC4 11 VAL B 309 ? VAL B 309 . ? 8_554 ? 21 AC4 11 LYS B 310 ? LYS B 310 . ? 8_554 ? 22 AC4 11 GLU B 311 ? GLU B 311 . ? 8_554 ? # _database_PDB_matrix.entry_id 4UTC _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 4UTC _atom_sites.fract_transf_matrix[1][1] 0.009482 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009482 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.006028 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . MET A 1 1 ? -34.968 10.422 -32.476 1.00 71.58 ? 1 MET A N 1 ATOM 2 C CA . MET A 1 1 ? -35.301 10.413 -33.901 1.00 71.29 ? 1 MET A CA 1 ATOM 3 C C . MET A 1 1 ? -34.271 9.592 -34.661 1.00 74.68 ? 1 MET A C 1 ATOM 4 O O . MET A 1 1 ? -34.377 9.459 -35.894 1.00 74.72 ? 1 MET A O 1 ATOM 5 C CB . MET A 1 1 ? -35.400 11.828 -34.472 1.00 74.22 ? 1 MET A CB 1 ATOM 6 C CG . MET A 1 1 ? -36.386 12.722 -33.745 1.00 79.52 ? 1 MET A CG 1 ATOM 7 S SD . MET A 1 1 ? -37.445 13.642 -34.891 1.00 85.53 ? 1 MET A SD 1 ATOM 8 C CE . MET A 1 1 ? -36.299 14.876 -35.473 1.00 82.40 ? 1 MET A CE 1 ATOM 9 N N . ARG A 1 2 ? -33.274 9.027 -33.910 1.00 69.53 ? 2 ARG A N 1 ATOM 10 C CA . ARG A 1 2 ? -32.199 8.162 -34.396 1.00 69.51 ? 2 ARG A CA 1 ATOM 11 C C . ARG A 1 2 ? -32.769 6.929 -35.091 1.00 73.39 ? 2 ARG A C 1 ATOM 12 O O . ARG A 1 2 ? -32.309 6.556 -36.173 1.00 73.49 ? 2 ARG A O 1 ATOM 13 C CB . ARG A 1 2 ? -31.321 7.692 -33.233 1.00 71.84 ? 2 ARG A CB 1 ATOM 14 C CG . ARG A 1 2 ? -30.364 8.742 -32.695 1.00 88.12 ? 2 ARG A CG 1 ATOM 15 C CD . ARG A 1 2 ? -29.538 8.195 -31.546 1.00 94.42 ? 2 ARG A CD 1 ATOM 16 N NE . ARG A 1 2 ? -28.132 8.581 -31.660 1.00 106.22 ? 2 ARG A NE 1 ATOM 17 C CZ . ARG A 1 2 ? -27.149 7.746 -31.989 1.00 121.78 ? 2 ARG A CZ 1 ATOM 18 N NH1 . ARG A 1 2 ? -27.406 6.463 -32.213 1.00 108.61 ? 2 ARG A NH1 1 ATOM 19 N NH2 . ARG A 1 2 ? -25.899 8.181 -32.069 1.00 104.17 ? 2 ARG A NH2 1 ATOM 20 N N . CYS A 1 3 ? -33.793 6.324 -34.472 1.00 69.93 ? 3 CYS A N 1 ATOM 21 C CA . CYS A 1 3 ? -34.484 5.120 -34.924 1.00 71.21 ? 3 CYS A CA 1 ATOM 22 C C . CYS A 1 3 ? -35.054 5.213 -36.318 1.00 71.59 ? 3 CYS A C 1 ATOM 23 O O . CYS A 1 3 ? -35.207 4.191 -36.984 1.00 70.22 ? 3 CYS A O 1 ATOM 24 C CB . CYS A 1 3 ? -35.561 4.727 -33.918 1.00 73.41 ? 3 CYS A CB 1 ATOM 25 S SG . CYS A 1 3 ? -34.952 4.467 -32.227 1.00 78.11 ? 3 CYS A SG 1 ATOM 26 N N . ILE A 1 4 ? -35.408 6.427 -36.744 1.00 67.30 ? 4 ILE A N 1 ATOM 27 C CA . ILE A 1 4 ? -35.959 6.662 -38.067 1.00 66.70 ? 4 ILE A CA 1 ATOM 28 C C . ILE A 1 4 ? -34.869 6.293 -39.091 1.00 70.05 ? 4 ILE A C 1 ATOM 29 O O . ILE A 1 4 ? -33.845 6.992 -39.202 1.00 70.40 ? 4 ILE A O 1 ATOM 30 C CB . ILE A 1 4 ? -36.472 8.126 -38.209 1.00 69.67 ? 4 ILE A CB 1 ATOM 31 C CG1 . ILE A 1 4 ? -37.457 8.512 -37.084 1.00 70.48 ? 4 ILE A CG1 1 ATOM 32 C CG2 . ILE A 1 4 ? -37.092 8.349 -39.567 1.00 70.01 ? 4 ILE A CG2 1 ATOM 33 C CD1 . ILE A 1 4 ? -37.640 10.041 -36.886 1.00 78.21 ? 4 ILE A CD1 1 ATOM 34 N N . GLY A 1 5 ? -35.083 5.162 -39.765 1.00 64.30 ? 5 GLY A N 1 ATOM 35 C CA . GLY A 1 5 ? -34.170 4.656 -40.785 1.00 63.74 ? 5 GLY A CA 1 ATOM 36 C C . GLY A 1 5 ? -33.653 3.253 -40.518 1.00 64.95 ? 5 GLY A C 1 ATOM 37 O O . GLY A 1 5 ? -33.328 2.513 -41.464 1.00 64.63 ? 5 GLY A O 1 ATOM 38 N N . ILE A 1 6 ? -33.567 2.900 -39.209 1.00 57.17 ? 6 ILE A N 1 ATOM 39 C CA . ILE A 1 6 ? -33.139 1.607 -38.649 1.00 54.24 ? 6 ILE A CA 1 ATOM 40 C C . ILE A 1 6 ? -34.283 0.579 -38.788 1.00 52.97 ? 6 ILE A C 1 ATOM 41 O O . ILE A 1 6 ? -35.361 0.778 -38.246 1.00 49.79 ? 6 ILE A O 1 ATOM 42 C CB . ILE A 1 6 ? -32.653 1.787 -37.155 1.00 56.78 ? 6 ILE A CB 1 ATOM 43 C CG1 . ILE A 1 6 ? -31.334 2.561 -37.076 1.00 56.08 ? 6 ILE A CG1 1 ATOM 44 C CG2 . ILE A 1 6 ? -32.543 0.453 -36.420 1.00 58.01 ? 6 ILE A CG2 1 ATOM 45 C CD1 . ILE A 1 6 ? -30.977 3.132 -35.715 1.00 63.58 ? 6 ILE A CD1 1 ATOM 46 N N . SER A 1 7 ? -34.022 -0.526 -39.481 1.00 51.62 ? 7 SER A N 1 ATOM 47 C CA . SER A 1 7 ? -34.969 -1.618 -39.692 1.00 52.75 ? 7 SER A CA 1 ATOM 48 C C . SER A 1 7 ? -35.240 -2.408 -38.418 1.00 62.39 ? 7 SER A C 1 ATOM 49 O O . SER A 1 7 ? -36.396 -2.768 -38.190 1.00 63.26 ? 7 SER A O 1 ATOM 50 C CB . SER A 1 7 ? -34.499 -2.553 -40.795 1.00 54.99 ? 7 SER A CB 1 ATOM 51 O OG . SER A 1 7 ? -33.242 -3.104 -40.450 1.00 65.86 ? 7 SER A OG 1 ATOM 52 N N . ASN A 1 8 ? -34.209 -2.693 -37.578 1.00 60.97 ? 8 ASN A N 1 ATOM 53 C CA . ASN A 1 8 ? -34.480 -3.440 -36.343 1.00 61.08 ? 8 ASN A CA 1 ATOM 54 C C . ASN A 1 8 ? -34.912 -2.472 -35.236 1.00 63.24 ? 8 ASN A C 1 ATOM 55 O O . ASN A 1 8 ? -34.138 -2.133 -34.330 1.00 61.24 ? 8 ASN A O 1 ATOM 56 C CB . ASN A 1 8 ? -33.321 -4.353 -35.943 1.00 66.20 ? 8 ASN A CB 1 ATOM 57 C CG . ASN A 1 8 ? -33.650 -5.231 -34.755 1.00 106.50 ? 8 ASN A CG 1 ATOM 58 O OD1 . ASN A 1 8 ? -34.806 -5.643 -34.548 1.00 97.09 ? 8 ASN A OD1 1 ATOM 59 N ND2 . ASN A 1 8 ? -32.641 -5.518 -33.932 1.00 106.29 ? 8 ASN A ND2 1 ATOM 60 N N . ARG A 1 9 ? -36.173 -2.023 -35.337 1.00 59.73 ? 9 ARG A N 1 ATOM 61 C CA . ARG A 1 9 ? -36.758 -1.020 -34.451 1.00 59.14 ? 9 ARG A CA 1 ATOM 62 C C . ARG A 1 9 ? -38.069 -1.457 -33.832 1.00 61.62 ? 9 ARG A C 1 ATOM 63 O O . ARG A 1 9 ? -38.916 -2.013 -34.526 1.00 60.42 ? 9 ARG A O 1 ATOM 64 C CB . ARG A 1 9 ? -36.956 0.258 -35.261 1.00 59.85 ? 9 ARG A CB 1 ATOM 65 C CG . ARG A 1 9 ? -37.493 1.419 -34.484 1.00 65.86 ? 9 ARG A CG 1 ATOM 66 C CD . ARG A 1 9 ? -38.150 2.344 -35.450 1.00 64.62 ? 9 ARG A CD 1 ATOM 67 N NE . ARG A 1 9 ? -38.607 3.557 -34.793 1.00 60.80 ? 9 ARG A NE 1 ATOM 68 C CZ . ARG A 1 9 ? -38.982 4.642 -35.449 1.00 74.70 ? 9 ARG A CZ 1 ATOM 69 N NH1 . ARG A 1 9 ? -38.977 4.658 -36.776 1.00 79.17 ? 9 ARG A NH1 1 ATOM 70 N NH2 . ARG A 1 9 ? -39.390 5.710 -34.791 1.00 50.75 ? 9 ARG A NH2 1 ATOM 71 N N . ASP A 1 10 ? -38.242 -1.184 -32.532 1.00 59.90 ? 10 ASP A N 1 ATOM 72 C CA . ASP A 1 10 ? -39.459 -1.532 -31.796 1.00 60.84 ? 10 ASP A CA 1 ATOM 73 C C . ASP A 1 10 ? -40.178 -0.283 -31.317 1.00 64.52 ? 10 ASP A C 1 ATOM 74 O O . ASP A 1 10 ? -39.536 0.697 -30.936 1.00 63.95 ? 10 ASP A O 1 ATOM 75 C CB . ASP A 1 10 ? -39.151 -2.456 -30.603 1.00 63.99 ? 10 ASP A CB 1 ATOM 76 C CG . ASP A 1 10 ? -38.292 -3.680 -30.921 1.00 86.89 ? 10 ASP A CG 1 ATOM 77 O OD1 . ASP A 1 10 ? -38.612 -4.394 -31.905 1.00 91.18 ? 10 ASP A OD1 1 ATOM 78 O OD2 . ASP A 1 10 ? -37.326 -3.954 -30.153 1.00 92.36 ? 10 ASP A OD2 1 ATOM 79 N N . PHE A 1 11 ? -41.510 -0.320 -31.330 1.00 62.07 ? 11 PHE A N 1 ATOM 80 C CA . PHE A 1 11 ? -42.363 0.778 -30.885 1.00 62.10 ? 11 PHE A CA 1 ATOM 81 C C . PHE A 1 11 ? -43.041 0.356 -29.591 1.00 66.44 ? 11 PHE A C 1 ATOM 82 O O . PHE A 1 11 ? -44.111 -0.240 -29.614 1.00 65.85 ? 11 PHE A O 1 ATOM 83 C CB . PHE A 1 11 ? -43.394 1.118 -31.969 1.00 64.05 ? 11 PHE A CB 1 ATOM 84 C CG . PHE A 1 11 ? -42.804 1.617 -33.266 1.00 66.06 ? 11 PHE A CG 1 ATOM 85 C CD1 . PHE A 1 11 ? -42.299 0.730 -34.206 1.00 69.26 ? 11 PHE A CD1 1 ATOM 86 C CD2 . PHE A 1 11 ? -42.757 2.977 -33.552 1.00 68.99 ? 11 PHE A CD2 1 ATOM 87 C CE1 . PHE A 1 11 ? -41.730 1.199 -35.401 1.00 71.87 ? 11 PHE A CE1 1 ATOM 88 C CE2 . PHE A 1 11 ? -42.205 3.443 -34.752 1.00 69.91 ? 11 PHE A CE2 1 ATOM 89 C CZ . PHE A 1 11 ? -41.709 2.551 -35.673 1.00 69.34 ? 11 PHE A CZ 1 ATOM 90 N N . VAL A 1 12 ? -42.371 0.596 -28.467 1.00 64.70 ? 12 VAL A N 1 ATOM 91 C CA . VAL A 1 12 ? -42.836 0.232 -27.118 1.00 65.59 ? 12 VAL A CA 1 ATOM 92 C C . VAL A 1 12 ? -43.769 1.324 -26.575 1.00 72.87 ? 12 VAL A C 1 ATOM 93 O O . VAL A 1 12 ? -43.329 2.456 -26.377 1.00 72.03 ? 12 VAL A O 1 ATOM 94 C CB . VAL A 1 12 ? -41.646 -0.032 -26.140 1.00 68.24 ? 12 VAL A CB 1 ATOM 95 C CG1 . VAL A 1 12 ? -42.130 -0.304 -24.718 1.00 67.48 ? 12 VAL A CG1 1 ATOM 96 C CG2 . VAL A 1 12 ? -40.762 -1.163 -26.639 1.00 67.97 ? 12 VAL A CG2 1 ATOM 97 N N . GLU A 1 13 ? -45.041 0.980 -26.317 1.00 71.87 ? 13 GLU A N 1 ATOM 98 C CA . GLU A 1 13 ? -45.988 1.932 -25.753 1.00 73.01 ? 13 GLU A CA 1 ATOM 99 C C . GLU A 1 13 ? -46.380 1.503 -24.358 1.00 79.65 ? 13 GLU A C 1 ATOM 100 O O . GLU A 1 13 ? -46.798 0.364 -24.144 1.00 79.16 ? 13 GLU A O 1 ATOM 101 C CB . GLU A 1 13 ? -47.220 2.151 -26.650 1.00 74.73 ? 13 GLU A CB 1 ATOM 102 C CG . GLU A 1 13 ? -48.020 3.393 -26.268 1.00 89.02 ? 13 GLU A CG 1 ATOM 103 C CD . GLU A 1 13 ? -49.225 3.734 -27.125 1.00 115.76 ? 13 GLU A CD 1 ATOM 104 O OE1 . GLU A 1 13 ? -49.809 2.808 -27.735 1.00 131.00 ? 13 GLU A OE1 1 ATOM 105 O OE2 . GLU A 1 13 ? -49.599 4.930 -27.168 1.00 100.32 ? 13 GLU A OE2 1 ATOM 106 N N . GLY A 1 14 ? -46.197 2.418 -23.421 1.00 78.85 ? 14 GLY A N 1 ATOM 107 C CA . GLY A 1 14 ? -46.510 2.190 -22.027 1.00 80.63 ? 14 GLY A CA 1 ATOM 108 C C . GLY A 1 14 ? -47.959 2.488 -21.756 1.00 90.99 ? 14 GLY A C 1 ATOM 109 O O . GLY A 1 14 ? -48.510 3.460 -22.296 1.00 91.23 ? 14 GLY A O 1 ATOM 110 N N . VAL A 1 15 ? -48.585 1.635 -20.922 1.00 91.56 ? 15 VAL A N 1 ATOM 111 C CA . VAL A 1 15 ? -49.964 1.824 -20.494 1.00 92.68 ? 15 VAL A CA 1 ATOM 112 C C . VAL A 1 15 ? -49.960 3.110 -19.693 1.00 99.12 ? 15 VAL A C 1 ATOM 113 O O . VAL A 1 15 ? -49.368 3.201 -18.614 1.00 98.31 ? 15 VAL A O 1 ATOM 114 C CB . VAL A 1 15 ? -50.575 0.624 -19.739 1.00 96.47 ? 15 VAL A CB 1 ATOM 115 C CG1 . VAL A 1 15 ? -51.998 0.937 -19.287 1.00 96.12 ? 15 VAL A CG1 1 ATOM 116 C CG2 . VAL A 1 15 ? -50.555 -0.617 -20.621 1.00 96.31 ? 15 VAL A CG2 1 ATOM 117 N N . SER A 1 16 ? -50.492 4.131 -20.359 1.00 98.20 ? 16 SER A N 1 ATOM 118 C CA . SER A 1 16 ? -50.634 5.532 -19.985 1.00 98.81 ? 16 SER A CA 1 ATOM 119 C C . SER A 1 16 ? -51.121 5.720 -18.553 1.00 102.47 ? 16 SER A C 1 ATOM 120 O O . SER A 1 16 ? -52.080 5.076 -18.111 1.00 101.39 ? 16 SER A O 1 ATOM 121 C CB . SER A 1 16 ? -51.518 6.236 -21.005 1.00 103.47 ? 16 SER A CB 1 ATOM 122 O OG . SER A 1 16 ? -51.061 5.939 -22.322 1.00 111.83 ? 16 SER A OG 1 ATOM 123 N N . GLY A 1 17 ? -50.375 6.543 -17.830 1.00 99.93 ? 17 GLY A N 1 ATOM 124 C CA . GLY A 1 17 ? -50.545 6.778 -16.402 1.00 100.23 ? 17 GLY A CA 1 ATOM 125 C C . GLY A 1 17 ? -49.366 6.179 -15.655 1.00 104.93 ? 17 GLY A C 1 ATOM 126 O O . GLY A 1 17 ? -48.809 6.816 -14.754 1.00 104.73 ? 17 GLY A O 1 ATOM 127 N N . GLY A 1 18 ? -48.975 4.965 -16.074 1.00 101.87 ? 18 GLY A N 1 ATOM 128 C CA . GLY A 1 18 ? -47.857 4.194 -15.540 1.00 101.76 ? 18 GLY A CA 1 ATOM 129 C C . GLY A 1 18 ? -46.563 4.981 -15.522 1.00 106.58 ? 18 GLY A C 1 ATOM 130 O O . GLY A 1 18 ? -46.249 5.691 -16.487 1.00 106.80 ? 18 GLY A O 1 ATOM 131 N N . SER A 1 19 ? -45.827 4.883 -14.391 1.00 102.09 ? 19 SER A N 1 ATOM 132 C CA . SER A 1 19 ? -44.569 5.583 -14.148 1.00 100.65 ? 19 SER A CA 1 ATOM 133 C C . SER A 1 19 ? -43.332 4.819 -14.617 1.00 103.90 ? 19 SER A C 1 ATOM 134 O O . SER A 1 19 ? -42.218 5.284 -14.399 1.00 103.30 ? 19 SER A O 1 ATOM 135 C CB . SER A 1 19 ? -44.460 5.965 -12.679 1.00 102.37 ? 19 SER A CB 1 ATOM 136 O OG . SER A 1 19 ? -45.412 6.972 -12.386 1.00 108.69 ? 19 SER A OG 1 ATOM 137 N N . TRP A 1 20 ? -43.523 3.660 -15.271 1.00 100.68 ? 20 TRP A N 1 ATOM 138 C CA . TRP A 1 20 ? -42.428 2.836 -15.790 1.00 100.47 ? 20 TRP A CA 1 ATOM 139 C C . TRP A 1 20 ? -42.784 2.156 -17.079 1.00 99.41 ? 20 TRP A C 1 ATOM 140 O O . TRP A 1 20 ? -43.956 1.842 -17.309 1.00 98.52 ? 20 TRP A O 1 ATOM 141 C CB . TRP A 1 20 ? -42.031 1.716 -14.824 1.00 100.58 ? 20 TRP A CB 1 ATOM 142 C CG . TRP A 1 20 ? -42.262 1.982 -13.377 1.00 102.67 ? 20 TRP A CG 1 ATOM 143 C CD1 . TRP A 1 20 ? -43.343 1.607 -12.629 1.00 105.79 ? 20 TRP A CD1 1 ATOM 144 C CD2 . TRP A 1 20 ? -41.350 2.618 -12.482 1.00 103.03 ? 20 TRP A CD2 1 ATOM 145 N NE1 . TRP A 1 20 ? -43.160 1.979 -11.317 1.00 105.55 ? 20 TRP A NE1 1 ATOM 146 C CE2 . TRP A 1 20 ? -41.945 2.606 -11.198 1.00 107.30 ? 20 TRP A CE2 1 ATOM 147 C CE3 . TRP A 1 20 ? -40.070 3.185 -12.635 1.00 104.52 ? 20 TRP A CE3 1 ATOM 148 C CZ2 . TRP A 1 20 ? -41.317 3.164 -10.081 1.00 106.84 ? 20 TRP A CZ2 1 ATOM 149 C CZ3 . TRP A 1 20 ? -39.454 3.749 -11.530 1.00 106.28 ? 20 TRP A CZ3 1 ATOM 150 C CH2 . TRP A 1 20 ? -40.077 3.743 -10.274 1.00 107.04 ? 20 TRP A CH2 1 ATOM 151 N N . VAL A 1 21 ? -41.759 1.822 -17.872 1.00 93.02 ? 21 VAL A N 1 ATOM 152 C CA . VAL A 1 21 ? -41.941 1.032 -19.087 1.00 92.14 ? 21 VAL A CA 1 ATOM 153 C C . VAL A 1 21 ? -40.728 0.136 -19.275 1.00 93.31 ? 21 VAL A C 1 ATOM 154 O O . VAL A 1 21 ? -39.594 0.577 -19.032 1.00 92.84 ? 21 VAL A O 1 ATOM 155 C CB . VAL A 1 21 ? -42.360 1.819 -20.363 1.00 96.14 ? 21 VAL A CB 1 ATOM 156 C CG1 . VAL A 1 21 ? -41.159 2.386 -21.120 1.00 95.99 ? 21 VAL A CG1 1 ATOM 157 C CG2 . VAL A 1 21 ? -43.216 0.949 -21.277 1.00 95.90 ? 21 VAL A CG2 1 ATOM 158 N N . ASP A 1 22 ? -40.967 -1.133 -19.660 1.00 87.47 ? 22 ASP A N 1 ATOM 159 C CA . ASP A 1 22 ? -39.859 -2.064 -19.818 1.00 86.56 ? 22 ASP A CA 1 ATOM 160 C C . ASP A 1 22 ? -39.394 -2.222 -21.249 1.00 86.69 ? 22 ASP A C 1 ATOM 161 O O . ASP A 1 22 ? -40.190 -2.551 -22.128 1.00 86.33 ? 22 ASP A O 1 ATOM 162 C CB . ASP A 1 22 ? -40.169 -3.417 -19.184 1.00 89.02 ? 22 ASP A CB 1 ATOM 163 C CG . ASP A 1 22 ? -39.956 -3.427 -17.692 1.00 102.66 ? 22 ASP A CG 1 ATOM 164 O OD1 . ASP A 1 22 ? -38.831 -3.069 -17.245 1.00 104.69 ? 22 ASP A OD1 1 ATOM 165 O OD2 . ASP A 1 22 ? -40.899 -3.811 -16.965 1.00 106.94 ? 22 ASP A OD2 1 ATOM 166 N N . ILE A 1 23 ? -38.097 -1.964 -21.478 1.00 80.51 ? 23 ILE A N 1 ATOM 167 C CA . ILE A 1 23 ? -37.461 -2.061 -22.793 1.00 79.24 ? 23 ILE A CA 1 ATOM 168 C C . ILE A 1 23 ? -36.207 -2.947 -22.766 1.00 83.00 ? 23 ILE A C 1 ATOM 169 O O . ILE A 1 23 ? -35.567 -3.099 -21.730 1.00 83.31 ? 23 ILE A O 1 ATOM 170 C CB . ILE A 1 23 ? -37.181 -0.685 -23.465 1.00 80.98 ? 23 ILE A CB 1 ATOM 171 C CG1 . ILE A 1 23 ? -36.230 0.186 -22.634 1.00 80.27 ? 23 ILE A CG1 1 ATOM 172 C CG2 . ILE A 1 23 ? -38.478 0.032 -23.800 1.00 81.66 ? 23 ILE A CG2 1 ATOM 173 C CD1 . ILE A 1 23 ? -35.445 1.198 -23.417 1.00 85.13 ? 23 ILE A CD1 1 ATOM 174 N N . VAL A 1 24 ? -35.866 -3.516 -23.928 1.00 78.15 ? 24 VAL A N 1 ATOM 175 C CA . VAL A 1 24 ? -34.706 -4.378 -24.147 1.00 76.71 ? 24 VAL A CA 1 ATOM 176 C C . VAL A 1 24 ? -33.793 -3.708 -25.161 1.00 79.37 ? 24 VAL A C 1 ATOM 177 O O . VAL A 1 24 ? -34.100 -3.676 -26.357 1.00 79.92 ? 24 VAL A O 1 ATOM 178 C CB . VAL A 1 24 ? -35.085 -5.809 -24.621 1.00 79.62 ? 24 VAL A CB 1 ATOM 179 C CG1 . VAL A 1 24 ? -33.875 -6.725 -24.556 1.00 79.05 ? 24 VAL A CG1 1 ATOM 180 C CG2 . VAL A 1 24 ? -36.242 -6.385 -23.819 1.00 79.48 ? 24 VAL A CG2 1 ATOM 181 N N . LEU A 1 25 ? -32.686 -3.174 -24.694 1.00 75.02 ? 25 LEU A N 1 ATOM 182 C CA . LEU A 1 25 ? -31.743 -2.562 -25.603 1.00 75.99 ? 25 LEU A CA 1 ATOM 183 C C . LEU A 1 25 ? -30.649 -3.555 -25.996 1.00 84.18 ? 25 LEU A C 1 ATOM 184 O O . LEU A 1 25 ? -30.165 -4.321 -25.150 1.00 86.52 ? 25 LEU A O 1 ATOM 185 C CB . LEU A 1 25 ? -31.141 -1.277 -25.017 1.00 75.90 ? 25 LEU A CB 1 ATOM 186 C CG . LEU A 1 25 ? -32.101 -0.119 -24.768 1.00 80.95 ? 25 LEU A CG 1 ATOM 187 C CD1 . LEU A 1 25 ? -31.348 1.095 -24.291 1.00 81.31 ? 25 LEU A CD1 1 ATOM 188 C CD2 . LEU A 1 25 ? -32.895 0.241 -26.027 1.00 84.05 ? 25 LEU A CD2 1 ATOM 189 N N . GLU A 1 26 ? -30.291 -3.572 -27.287 1.00 79.83 ? 26 GLU A N 1 ATOM 190 C CA . GLU A 1 26 ? -29.226 -4.422 -27.808 1.00 78.84 ? 26 GLU A CA 1 ATOM 191 C C . GLU A 1 26 ? -28.530 -3.728 -28.973 1.00 80.04 ? 26 GLU A C 1 ATOM 192 O O . GLU A 1 26 ? -28.959 -2.645 -29.385 1.00 78.96 ? 26 GLU A O 1 ATOM 193 C CB . GLU A 1 26 ? -29.687 -5.871 -28.112 1.00 79.96 ? 26 GLU A CB 1 ATOM 194 C CG . GLU A 1 26 ? -30.592 -6.051 -29.307 1.00 87.88 ? 26 GLU A CG 1 ATOM 195 C CD . GLU A 1 26 ? -31.016 -7.487 -29.544 1.00 117.73 ? 26 GLU A CD 1 ATOM 196 O OE1 . GLU A 1 26 ? -30.132 -8.376 -29.606 1.00 113.10 ? 26 GLU A OE1 1 ATOM 197 O OE2 . GLU A 1 26 ? -32.241 -7.725 -29.651 1.00 121.76 ? 26 GLU A OE2 1 ATOM 198 N N . HIS A 1 27 ? -27.409 -4.299 -29.437 1.00 75.28 ? 27 HIS A N 1 ATOM 199 C CA . HIS A 1 27 ? -26.620 -3.703 -30.502 1.00 74.32 ? 27 HIS A CA 1 ATOM 200 C C . HIS A 1 27 ? -27.274 -3.951 -31.829 1.00 76.33 ? 27 HIS A C 1 ATOM 201 O O . HIS A 1 27 ? -27.786 -5.048 -32.061 1.00 75.58 ? 27 HIS A O 1 ATOM 202 C CB . HIS A 1 27 ? -25.170 -4.203 -30.466 1.00 75.08 ? 27 HIS A CB 1 ATOM 203 C CG . HIS A 1 27 ? -24.324 -3.491 -29.458 1.00 78.42 ? 27 HIS A CG 1 ATOM 204 N ND1 . HIS A 1 27 ? -23.541 -2.401 -29.816 1.00 80.21 ? 27 HIS A ND1 1 ATOM 205 C CD2 . HIS A 1 27 ? -24.173 -3.724 -28.131 1.00 79.88 ? 27 HIS A CD2 1 ATOM 206 C CE1 . HIS A 1 27 ? -22.937 -2.012 -28.700 1.00 79.40 ? 27 HIS A CE1 1 ATOM 207 N NE2 . HIS A 1 27 ? -23.289 -2.775 -27.658 1.00 79.63 ? 27 HIS A NE2 1 ATOM 208 N N . GLY A 1 28 ? -27.319 -2.901 -32.646 1.00 72.71 ? 28 GLY A N 1 ATOM 209 C CA . GLY A 1 28 ? -27.928 -2.894 -33.976 1.00 72.72 ? 28 GLY A CA 1 ATOM 210 C C . GLY A 1 28 ? -29.433 -2.748 -33.953 1.00 76.70 ? 28 GLY A C 1 ATOM 211 O O . GLY A 1 28 ? -30.104 -2.948 -34.974 1.00 76.26 ? 28 GLY A O 1 ATOM 212 N N . SER A 1 29 ? -29.957 -2.406 -32.771 1.00 73.42 ? 29 SER A N 1 ATOM 213 C CA . SER A 1 29 ? -31.370 -2.264 -32.472 1.00 73.93 ? 29 SER A CA 1 ATOM 214 C C . SER A 1 29 ? -31.640 -0.893 -31.853 1.00 78.33 ? 29 SER A C 1 ATOM 215 O O . SER A 1 29 ? -30.880 -0.415 -31.002 1.00 77.98 ? 29 SER A O 1 ATOM 216 C CB . SER A 1 29 ? -31.831 -3.396 -31.543 1.00 78.82 ? 29 SER A CB 1 ATOM 217 O OG . SER A 1 29 ? -32.988 -3.137 -30.756 1.00 91.15 ? 29 SER A OG 1 ATOM 218 N N . CYS A 1 30 ? -32.760 -0.289 -32.272 1.00 74.73 ? 30 CYS A N 1 ATOM 219 C CA . CYS A 1 30 ? -33.255 0.992 -31.791 1.00 73.75 ? 30 CYS A CA 1 ATOM 220 C C . CYS A 1 30 ? -34.620 0.792 -31.138 1.00 76.20 ? 30 CYS A C 1 ATOM 221 O O . CYS A 1 30 ? -35.352 -0.122 -31.529 1.00 76.04 ? 30 CYS A O 1 ATOM 222 C CB . CYS A 1 30 ? -33.342 1.973 -32.949 1.00 74.14 ? 30 CYS A CB 1 ATOM 223 S SG . CYS A 1 30 ? -33.082 3.686 -32.457 1.00 78.31 ? 30 CYS A SG 1 ATOM 224 N N . VAL A 1 31 ? -34.973 1.627 -30.151 1.00 71.67 ? 31 VAL A N 1 ATOM 225 C CA . VAL A 1 31 ? -36.287 1.531 -29.494 1.00 70.98 ? 31 VAL A CA 1 ATOM 226 C C . VAL A 1 31 ? -37.015 2.895 -29.405 1.00 73.37 ? 31 VAL A C 1 ATOM 227 O O . VAL A 1 31 ? -36.413 3.886 -28.992 1.00 72.66 ? 31 VAL A O 1 ATOM 228 C CB . VAL A 1 31 ? -36.175 0.842 -28.129 1.00 74.89 ? 31 VAL A CB 1 ATOM 229 C CG1 . VAL A 1 31 ? -37.436 1.049 -27.299 1.00 74.38 ? 31 VAL A CG1 1 ATOM 230 C CG2 . VAL A 1 31 ? -35.876 -0.644 -28.293 1.00 74.93 ? 31 VAL A CG2 1 ATOM 231 N N . THR A 1 32 ? -38.303 2.934 -29.788 1.00 68.39 ? 32 THR A N 1 ATOM 232 C CA . THR A 1 32 ? -39.116 4.147 -29.720 1.00 67.63 ? 32 THR A CA 1 ATOM 233 C C . THR A 1 32 ? -40.192 3.950 -28.636 1.00 71.12 ? 32 THR A C 1 ATOM 234 O O . THR A 1 32 ? -41.004 3.023 -28.737 1.00 69.70 ? 32 THR A O 1 ATOM 235 C CB . THR A 1 32 ? -39.658 4.504 -31.110 1.00 74.86 ? 32 THR A CB 1 ATOM 236 O OG1 . THR A 1 32 ? -38.562 4.766 -31.979 1.00 75.80 ? 32 THR A OG1 1 ATOM 237 C CG2 . THR A 1 32 ? -40.560 5.713 -31.095 1.00 72.61 ? 32 THR A CG2 1 ATOM 238 N N . THR A 1 33 ? -40.176 4.809 -27.592 1.00 67.17 ? 33 THR A N 1 ATOM 239 C CA . THR A 1 33 ? -41.106 4.726 -26.464 1.00 66.45 ? 33 THR A CA 1 ATOM 240 C C . THR A 1 33 ? -42.082 5.873 -26.407 1.00 70.61 ? 33 THR A C 1 ATOM 241 O O . THR A 1 33 ? -41.688 7.036 -26.476 1.00 69.33 ? 33 THR A O 1 ATOM 242 C CB . THR A 1 33 ? -40.362 4.601 -25.148 1.00 76.80 ? 33 THR A CB 1 ATOM 243 O OG1 . THR A 1 33 ? -39.530 5.745 -24.982 1.00 79.85 ? 33 THR A OG1 1 ATOM 244 C CG2 . THR A 1 33 ? -39.530 3.344 -25.070 1.00 76.89 ? 33 THR A CG2 1 ATOM 245 N N . MET A 1 34 ? -43.363 5.534 -26.232 1.00 68.71 ? 34 MET A N 1 ATOM 246 C CA . MET A 1 34 ? -44.489 6.465 -26.174 1.00 68.39 ? 34 MET A CA 1 ATOM 247 C C . MET A 1 34 ? -45.373 6.191 -24.979 1.00 72.16 ? 34 MET A C 1 ATOM 248 O O . MET A 1 34 ? -45.512 5.048 -24.557 1.00 71.56 ? 34 MET A O 1 ATOM 249 C CB . MET A 1 34 ? -45.337 6.334 -27.438 1.00 70.83 ? 34 MET A CB 1 ATOM 250 C CG . MET A 1 34 ? -44.553 6.467 -28.723 1.00 75.07 ? 34 MET A CG 1 ATOM 251 S SD . MET A 1 34 ? -45.443 5.745 -30.123 1.00 80.31 ? 34 MET A SD 1 ATOM 252 C CE . MET A 1 34 ? -46.548 7.128 -30.514 1.00 77.61 ? 34 MET A CE 1 ATOM 253 N N . ALA A 1 35 ? -45.995 7.244 -24.448 1.00 69.87 ? 35 ALA A N 1 ATOM 254 C CA . ALA A 1 35 ? -46.947 7.204 -23.329 1.00 69.72 ? 35 ALA A CA 1 ATOM 255 C C . ALA A 1 35 ? -47.854 8.417 -23.450 1.00 74.29 ? 35 ALA A C 1 ATOM 256 O O . ALA A 1 35 ? -47.393 9.449 -23.960 1.00 74.08 ? 35 ALA A O 1 ATOM 257 C CB . ALA A 1 35 ? -46.204 7.240 -22.002 1.00 70.19 ? 35 ALA A CB 1 ATOM 258 N N . LYS A 1 36 ? -49.138 8.305 -23.014 1.00 71.04 ? 36 LYS A N 1 ATOM 259 C CA . LYS A 1 36 ? -50.074 9.440 -23.097 1.00 70.97 ? 36 LYS A CA 1 ATOM 260 C C . LYS A 1 36 ? -49.583 10.618 -22.275 1.00 75.90 ? 36 LYS A C 1 ATOM 261 O O . LYS A 1 36 ? -49.228 10.446 -21.104 1.00 75.46 ? 36 LYS A O 1 ATOM 262 C CB . LYS A 1 36 ? -51.515 9.072 -22.732 1.00 73.24 ? 36 LYS A CB 1 ATOM 263 C CG . LYS A 1 36 ? -52.522 10.155 -23.086 1.00 101.64 ? 36 LYS A CG 1 ATOM 264 C CD . LYS A 1 36 ? -53.967 9.771 -22.772 1.00 123.37 ? 36 LYS A CD 1 ATOM 265 C CE . LYS A 1 36 ? -54.925 10.931 -22.989 1.00 139.45 ? 36 LYS A CE 1 ATOM 266 N NZ . LYS A 1 36 ? -55.917 10.694 -24.091 1.00 146.90 ? 36 LYS A NZ 1 ATOM 267 N N . ASN A 1 37 ? -49.509 11.802 -22.937 1.00 72.96 ? 37 ASN A N 1 ATOM 268 C CA . ASN A 1 37 ? -49.063 13.106 -22.417 1.00 72.20 ? 37 ASN A CA 1 ATOM 269 C C . ASN A 1 37 ? -47.613 13.065 -21.906 1.00 74.54 ? 37 ASN A C 1 ATOM 270 O O . ASN A 1 37 ? -47.239 13.795 -20.991 1.00 74.99 ? 37 ASN A O 1 ATOM 271 C CB . ASN A 1 37 ? -50.048 13.702 -21.385 1.00 69.53 ? 37 ASN A CB 1 ATOM 272 C CG . ASN A 1 37 ? -51.406 13.943 -21.968 1.00 98.72 ? 37 ASN A CG 1 ATOM 273 O OD1 . ASN A 1 37 ? -52.386 13.259 -21.633 1.00 100.63 ? 37 ASN A OD1 1 ATOM 274 N ND2 . ASN A 1 37 ? -51.472 14.846 -22.932 1.00 89.90 ? 37 ASN A ND2 1 ATOM 275 N N . LYS A 1 38 ? -46.794 12.236 -22.545 1.00 69.27 ? 38 LYS A N 1 ATOM 276 C CA . LYS A 1 38 ? -45.373 12.100 -22.243 1.00 68.50 ? 38 LYS A CA 1 ATOM 277 C C . LYS A 1 38 ? -44.634 12.148 -23.580 1.00 70.33 ? 38 LYS A C 1 ATOM 278 O O . LYS A 1 38 ? -45.195 11.753 -24.615 1.00 69.70 ? 38 LYS A O 1 ATOM 279 C CB . LYS A 1 38 ? -45.054 10.800 -21.463 1.00 70.57 ? 38 LYS A CB 1 ATOM 280 C CG . LYS A 1 38 ? -45.717 10.673 -20.083 1.00 82.13 ? 38 LYS A CG 1 ATOM 281 C CD . LYS A 1 38 ? -45.069 11.525 -19.000 1.00 87.66 ? 38 LYS A CD 1 ATOM 282 C CE . LYS A 1 38 ? -45.751 11.323 -17.669 1.00 92.25 ? 38 LYS A CE 1 ATOM 283 N NZ . LYS A 1 38 ? -45.073 12.071 -16.575 1.00 96.78 ? 38 LYS A NZ 1 ATOM 284 N N . PRO A 1 39 ? -43.397 12.655 -23.598 1.00 65.67 ? 39 PRO A N 1 ATOM 285 C CA . PRO A 1 39 ? -42.691 12.760 -24.870 1.00 66.14 ? 39 PRO A CA 1 ATOM 286 C C . PRO A 1 39 ? -42.198 11.436 -25.421 1.00 69.35 ? 39 PRO A C 1 ATOM 287 O O . PRO A 1 39 ? -41.821 10.536 -24.660 1.00 70.19 ? 39 PRO A O 1 ATOM 288 C CB . PRO A 1 39 ? -41.519 13.689 -24.559 1.00 68.62 ? 39 PRO A CB 1 ATOM 289 C CG . PRO A 1 39 ? -41.693 14.124 -23.151 1.00 72.77 ? 39 PRO A CG 1 ATOM 290 C CD . PRO A 1 39 ? -42.582 13.172 -22.487 1.00 67.60 ? 39 PRO A CD 1 ATOM 291 N N . THR A 1 40 ? -42.189 11.329 -26.755 1.00 63.42 ? 40 THR A N 1 ATOM 292 C CA . THR A 1 40 ? -41.701 10.146 -27.442 1.00 61.97 ? 40 THR A CA 1 ATOM 293 C C . THR A 1 40 ? -40.167 10.150 -27.415 1.00 64.38 ? 40 THR A C 1 ATOM 294 O O . THR A 1 40 ? -39.545 11.160 -27.738 1.00 65.45 ? 40 THR A O 1 ATOM 295 C CB . THR A 1 40 ? -42.362 10.031 -28.806 1.00 65.76 ? 40 THR A CB 1 ATOM 296 O OG1 . THR A 1 40 ? -43.767 9.834 -28.596 1.00 66.10 ? 40 THR A OG1 1 ATOM 297 C CG2 . THR A 1 40 ? -41.806 8.893 -29.626 1.00 63.36 ? 40 THR A CG2 1 ATOM 298 N N . LEU A 1 41 ? -39.570 9.042 -26.957 1.00 58.63 ? 41 LEU A N 1 ATOM 299 C CA . LEU A 1 41 ? -38.113 8.905 -26.844 1.00 57.20 ? 41 LEU A CA 1 ATOM 300 C C . LEU A 1 41 ? -37.523 7.754 -27.659 1.00 59.81 ? 41 LEU A C 1 ATOM 301 O O . LEU A 1 41 ? -38.132 6.674 -27.788 1.00 55.57 ? 41 LEU A O 1 ATOM 302 C CB . LEU A 1 41 ? -37.685 8.733 -25.388 1.00 56.71 ? 41 LEU A CB 1 ATOM 303 C CG . LEU A 1 41 ? -37.973 9.833 -24.416 1.00 59.42 ? 41 LEU A CG 1 ATOM 304 C CD1 . LEU A 1 41 ? -37.666 9.357 -23.046 1.00 59.89 ? 41 LEU A CD1 1 ATOM 305 C CD2 . LEU A 1 41 ? -37.144 11.033 -24.689 1.00 58.38 ? 41 LEU A CD2 1 ATOM 306 N N . ASP A 1 42 ? -36.286 7.993 -28.150 1.00 58.74 ? 42 ASP A N 1 ATOM 307 C CA . ASP A 1 42 ? -35.504 7.053 -28.942 1.00 60.01 ? 42 ASP A CA 1 ATOM 308 C C . ASP A 1 42 ? -34.284 6.562 -28.177 1.00 65.00 ? 42 ASP A C 1 ATOM 309 O O . ASP A 1 42 ? -33.510 7.370 -27.692 1.00 63.97 ? 42 ASP A O 1 ATOM 310 C CB . ASP A 1 42 ? -35.118 7.683 -30.291 1.00 62.12 ? 42 ASP A CB 1 ATOM 311 C CG . ASP A 1 42 ? -36.170 7.548 -31.379 1.00 73.71 ? 42 ASP A CG 1 ATOM 312 O OD1 . ASP A 1 42 ? -37.354 7.308 -31.043 1.00 75.41 ? 42 ASP A OD1 1 ATOM 313 O OD2 . ASP A 1 42 ? -35.802 7.618 -32.563 1.00 78.25 ? 42 ASP A OD2 1 ATOM 314 N N . PHE A 1 43 ? -34.128 5.238 -28.053 1.00 63.99 ? 43 PHE A N 1 ATOM 315 C CA . PHE A 1 43 ? -33.017 4.632 -27.320 1.00 64.97 ? 43 PHE A CA 1 ATOM 316 C C . PHE A 1 43 ? -32.181 3.700 -28.179 1.00 69.74 ? 43 PHE A C 1 ATOM 317 O O . PHE A 1 43 ? -32.726 2.854 -28.908 1.00 69.22 ? 43 PHE A O 1 ATOM 318 C CB . PHE A 1 43 ? -33.550 3.826 -26.134 1.00 67.24 ? 43 PHE A CB 1 ATOM 319 C CG . PHE A 1 43 ? -34.351 4.595 -25.126 1.00 69.03 ? 43 PHE A CG 1 ATOM 320 C CD1 . PHE A 1 43 ? -35.723 4.728 -25.264 1.00 72.06 ? 43 PHE A CD1 1 ATOM 321 C CD2 . PHE A 1 43 ? -33.744 5.140 -24.009 1.00 72.50 ? 43 PHE A CD2 1 ATOM 322 C CE1 . PHE A 1 43 ? -36.468 5.427 -24.318 1.00 75.63 ? 43 PHE A CE1 1 ATOM 323 C CE2 . PHE A 1 43 ? -34.491 5.817 -23.054 1.00 73.77 ? 43 PHE A CE2 1 ATOM 324 C CZ . PHE A 1 43 ? -35.843 5.976 -23.223 1.00 73.81 ? 43 PHE A CZ 1 ATOM 325 N N . GLU A 1 44 ? -30.858 3.814 -28.033 1.00 68.09 ? 44 GLU A N 1 ATOM 326 C CA . GLU A 1 44 ? -29.878 2.958 -28.702 1.00 69.91 ? 44 GLU A CA 1 ATOM 327 C C . GLU A 1 44 ? -28.744 2.590 -27.732 1.00 79.38 ? 44 GLU A C 1 ATOM 328 O O . GLU A 1 44 ? -28.352 3.409 -26.889 1.00 78.90 ? 44 GLU A O 1 ATOM 329 C CB . GLU A 1 44 ? -29.279 3.649 -29.935 1.00 70.85 ? 44 GLU A CB 1 ATOM 330 C CG . GLU A 1 44 ? -28.733 2.665 -30.953 1.00 78.91 ? 44 GLU A CG 1 ATOM 331 C CD . GLU A 1 44 ? -28.182 3.236 -32.242 1.00 104.73 ? 44 GLU A CD 1 ATOM 332 O OE1 . GLU A 1 44 ? -28.812 4.158 -32.807 1.00 105.39 ? 44 GLU A OE1 1 ATOM 333 O OE2 . GLU A 1 44 ? -27.168 2.693 -32.738 1.00 102.08 ? 44 GLU A OE2 1 ATOM 334 N N . LEU A 1 45 ? -28.226 1.362 -27.857 1.00 78.32 ? 45 LEU A N 1 ATOM 335 C CA . LEU A 1 45 ? -27.068 0.926 -27.098 1.00 78.96 ? 45 LEU A CA 1 ATOM 336 C C . LEU A 1 45 ? -25.918 1.133 -28.055 1.00 85.71 ? 45 LEU A C 1 ATOM 337 O O . LEU A 1 45 ? -25.862 0.456 -29.078 1.00 86.39 ? 45 LEU A O 1 ATOM 338 C CB . LEU A 1 45 ? -27.214 -0.546 -26.718 1.00 78.98 ? 45 LEU A CB 1 ATOM 339 C CG . LEU A 1 45 ? -26.116 -1.164 -25.882 1.00 82.78 ? 45 LEU A CG 1 ATOM 340 C CD1 . LEU A 1 45 ? -25.781 -0.311 -24.663 1.00 82.35 ? 45 LEU A CD1 1 ATOM 341 C CD2 . LEU A 1 45 ? -26.512 -2.556 -25.471 1.00 84.83 ? 45 LEU A CD2 1 ATOM 342 N N . ILE A 1 46 ? -25.076 2.136 -27.787 1.00 84.38 ? 46 ILE A N 1 ATOM 343 C CA . ILE A 1 46 ? -23.954 2.539 -28.628 1.00 86.10 ? 46 ILE A CA 1 ATOM 344 C C . ILE A 1 46 ? -22.716 1.638 -28.444 1.00 93.59 ? 46 ILE A C 1 ATOM 345 O O . ILE A 1 46 ? -22.169 1.169 -29.451 1.00 93.06 ? 46 ILE A O 1 ATOM 346 C CB . ILE A 1 46 ? -23.661 4.055 -28.435 1.00 90.03 ? 46 ILE A CB 1 ATOM 347 C CG1 . ILE A 1 46 ? -24.694 4.907 -29.180 1.00 90.35 ? 46 ILE A CG1 1 ATOM 348 C CG2 . ILE A 1 46 ? -22.220 4.464 -28.827 1.00 93.01 ? 46 ILE A CG2 1 ATOM 349 C CD1 . ILE A 1 46 ? -24.885 4.602 -30.729 1.00 101.87 ? 46 ILE A CD1 1 ATOM 350 N N . LYS A 1 47 ? -22.270 1.407 -27.183 1.00 93.03 ? 47 LYS A N 1 ATOM 351 C CA . LYS A 1 47 ? -21.120 0.538 -26.900 1.00 93.83 ? 47 LYS A CA 1 ATOM 352 C C . LYS A 1 47 ? -21.208 -0.184 -25.555 1.00 99.05 ? 47 LYS A C 1 ATOM 353 O O . LYS A 1 47 ? -21.813 0.308 -24.603 1.00 97.45 ? 47 LYS A O 1 ATOM 354 C CB . LYS A 1 47 ? -19.768 1.281 -27.047 1.00 96.62 ? 47 LYS A CB 1 ATOM 355 C CG . LYS A 1 47 ? -19.466 2.325 -25.984 1.00 112.62 ? 47 LYS A CG 1 ATOM 356 C CD . LYS A 1 47 ? -18.394 3.308 -26.446 1.00 121.92 ? 47 LYS A CD 1 ATOM 357 C CE . LYS A 1 47 ? -18.245 4.484 -25.507 1.00 128.87 ? 47 LYS A CE 1 ATOM 358 N NZ . LYS A 1 47 ? -17.268 4.197 -24.422 1.00 131.39 ? 47 LYS A NZ 1 ATOM 359 N N . THR A 1 48 ? -20.599 -1.373 -25.519 1.00 98.94 ? 48 THR A N 1 ATOM 360 C CA . THR A 1 48 ? -20.413 -2.261 -24.366 1.00 100.37 ? 48 THR A CA 1 ATOM 361 C C . THR A 1 48 ? -18.881 -2.340 -24.234 1.00 108.61 ? 48 THR A C 1 ATOM 362 O O . THR A 1 48 ? -18.191 -2.475 -25.255 1.00 108.14 ? 48 THR A O 1 ATOM 363 C CB . THR A 1 48 ? -21.079 -3.625 -24.620 1.00 107.46 ? 48 THR A CB 1 ATOM 364 O OG1 . THR A 1 48 ? -22.429 -3.445 -25.058 1.00 104.90 ? 48 THR A OG1 1 ATOM 365 C CG2 . THR A 1 48 ? -21.041 -4.530 -23.409 1.00 106.60 ? 48 THR A CG2 1 ATOM 366 N N . GLU A 1 49 ? -18.347 -2.173 -23.002 1.00 108.11 ? 49 GLU A N 1 ATOM 367 C CA . GLU A 1 49 ? -16.897 -2.105 -22.762 1.00 108.60 ? 49 GLU A CA 1 ATOM 368 C C . GLU A 1 49 ? -16.448 -2.714 -21.411 1.00 113.33 ? 49 GLU A C 1 ATOM 369 O O . GLU A 1 49 ? -17.172 -2.624 -20.413 1.00 112.15 ? 49 GLU A O 1 ATOM 370 C CB . GLU A 1 49 ? -16.460 -0.627 -22.861 1.00 109.91 ? 49 GLU A CB 1 ATOM 371 C CG . GLU A 1 49 ? -14.966 -0.374 -22.831 1.00 122.71 ? 49 GLU A CG 1 ATOM 372 C CD . GLU A 1 49 ? -14.532 0.602 -21.754 1.00 152.83 ? 49 GLU A CD 1 ATOM 373 O OE1 . GLU A 1 49 ? -14.852 1.807 -21.876 1.00 145.99 ? 49 GLU A OE1 1 ATOM 374 O OE2 . GLU A 1 49 ? -13.874 0.161 -20.784 1.00 161.11 ? 49 GLU A OE2 1 ATOM 375 N N . ALA A 1 50 ? -15.230 -3.313 -21.394 1.00 110.63 ? 50 ALA A N 1 ATOM 376 C CA . ALA A 1 50 ? -14.609 -3.884 -20.204 1.00 110.20 ? 50 ALA A CA 1 ATOM 377 C C . ALA A 1 50 ? -13.538 -2.914 -19.690 1.00 114.35 ? 50 ALA A C 1 ATOM 378 O O . ALA A 1 50 ? -12.622 -2.534 -20.431 1.00 112.72 ? 50 ALA A O 1 ATOM 379 C CB . ALA A 1 50 ? -14.015 -5.242 -20.526 1.00 110.73 ? 50 ALA A CB 1 ATOM 380 N N . LYS A 1 51 ? -13.712 -2.440 -18.445 1.00 112.93 ? 51 LYS A N 1 ATOM 381 C CA . LYS A 1 51 ? -12.777 -1.504 -17.810 1.00 113.74 ? 51 LYS A CA 1 ATOM 382 C C . LYS A 1 51 ? -11.603 -2.277 -17.147 1.00 119.58 ? 51 LYS A C 1 ATOM 383 O O . LYS A 1 51 ? -11.790 -2.922 -16.107 1.00 120.00 ? 51 LYS A O 1 ATOM 384 C CB . LYS A 1 51 ? -13.501 -0.568 -16.811 1.00 115.53 ? 51 LYS A CB 1 ATOM 385 C CG . LYS A 1 51 ? -14.106 0.684 -17.446 1.00 118.97 ? 51 LYS A CG 1 ATOM 386 C CD . LYS A 1 51 ? -13.890 1.958 -16.595 1.00 121.74 ? 51 LYS A CD 1 ATOM 387 C CE . LYS A 1 51 ? -14.449 3.208 -17.256 1.00 119.36 ? 51 LYS A CE 1 ATOM 388 N NZ . LYS A 1 51 ? -13.800 4.466 -16.774 1.00 117.04 ? 51 LYS A NZ 1 ATOM 389 N N . GLN A 1 52 ? -10.403 -2.233 -17.786 1.00 115.30 ? 52 GLN A N 1 ATOM 390 C CA . GLN A 1 52 ? -9.173 -2.899 -17.341 1.00 114.64 ? 52 GLN A CA 1 ATOM 391 C C . GLN A 1 52 ? -9.345 -4.456 -17.083 1.00 114.71 ? 52 GLN A C 1 ATOM 392 O O . GLN A 1 52 ? -9.389 -4.899 -15.921 1.00 113.50 ? 52 GLN A O 1 ATOM 393 C CB . GLN A 1 52 ? -8.556 -2.165 -16.121 1.00 116.41 ? 52 GLN A CB 1 ATOM 394 C CG . GLN A 1 52 ? -7.025 -2.027 -16.173 1.00 137.59 ? 52 GLN A CG 1 ATOM 395 C CD . GLN A 1 52 ? -6.463 -1.395 -14.923 1.00 158.15 ? 52 GLN A CD 1 ATOM 396 O OE1 . GLN A 1 52 ? -6.603 -0.193 -14.703 1.00 155.43 ? 52 GLN A OE1 1 ATOM 397 N NE2 . GLN A 1 52 ? -5.799 -2.188 -14.087 1.00 146.75 ? 52 GLN A NE2 1 ATOM 398 N N . PRO A 1 53 ? -9.423 -5.289 -18.161 1.00 108.14 ? 53 PRO A N 1 ATOM 399 C CA . PRO A 1 53 ? -9.534 -6.747 -17.946 1.00 106.02 ? 53 PRO A CA 1 ATOM 400 C C . PRO A 1 53 ? -8.158 -7.396 -17.820 1.00 105.43 ? 53 PRO A C 1 ATOM 401 O O . PRO A 1 53 ? -7.205 -7.011 -18.517 1.00 105.16 ? 53 PRO A O 1 ATOM 402 C CB . PRO A 1 53 ? -10.275 -7.238 -19.189 1.00 107.66 ? 53 PRO A CB 1 ATOM 403 C CG . PRO A 1 53 ? -10.035 -6.175 -20.247 1.00 112.64 ? 53 PRO A CG 1 ATOM 404 C CD . PRO A 1 53 ? -9.417 -4.956 -19.607 1.00 108.85 ? 53 PRO A CD 1 ATOM 405 N N . ALA A 1 54 ? -8.046 -8.383 -16.933 1.00 98.01 ? 54 ALA A N 1 ATOM 406 C CA . ALA A 1 54 ? -6.764 -9.056 -16.712 1.00 95.86 ? 54 ALA A CA 1 ATOM 407 C C . ALA A 1 54 ? -6.489 -10.114 -17.777 1.00 94.09 ? 54 ALA A C 1 ATOM 408 O O . ALA A 1 54 ? -7.265 -11.061 -17.860 1.00 93.70 ? 54 ALA A O 1 ATOM 409 C CB . ALA A 1 54 ? -6.736 -9.689 -15.321 1.00 96.63 ? 54 ALA A CB 1 ATOM 410 N N . THR A 1 55 ? -5.376 -9.997 -18.567 1.00 85.17 ? 55 THR A N 1 ATOM 411 C CA . THR A 1 55 ? -4.989 -11.026 -19.562 1.00 81.69 ? 55 THR A CA 1 ATOM 412 C C . THR A 1 55 ? -4.756 -12.344 -18.798 1.00 76.54 ? 55 THR A C 1 ATOM 413 O O . THR A 1 55 ? -3.799 -12.438 -18.036 1.00 76.67 ? 55 THR A O 1 ATOM 414 C CB . THR A 1 55 ? -3.743 -10.584 -20.358 1.00 91.61 ? 55 THR A CB 1 ATOM 415 O OG1 . THR A 1 55 ? -4.084 -9.445 -21.142 1.00 96.81 ? 55 THR A OG1 1 ATOM 416 C CG2 . THR A 1 55 ? -3.218 -11.672 -21.282 1.00 90.17 ? 55 THR A CG2 1 ATOM 417 N N . LEU A 1 56 ? -5.676 -13.310 -18.915 1.00 65.45 ? 56 LEU A N 1 ATOM 418 C CA . LEU A 1 56 ? -5.542 -14.557 -18.169 1.00 61.97 ? 56 LEU A CA 1 ATOM 419 C C . LEU A 1 56 ? -4.331 -15.320 -18.668 1.00 64.80 ? 56 LEU A C 1 ATOM 420 O O . LEU A 1 56 ? -3.374 -15.495 -17.925 1.00 64.55 ? 56 LEU A O 1 ATOM 421 C CB . LEU A 1 56 ? -6.840 -15.409 -18.265 1.00 60.47 ? 56 LEU A CB 1 ATOM 422 C CG . LEU A 1 56 ? -6.925 -16.756 -17.547 1.00 61.89 ? 56 LEU A CG 1 ATOM 423 C CD1 . LEU A 1 56 ? -6.384 -16.684 -16.160 1.00 61.46 ? 56 LEU A CD1 1 ATOM 424 C CD2 . LEU A 1 56 ? -8.344 -17.221 -17.464 1.00 60.92 ? 56 LEU A CD2 1 ATOM 425 N N . ARG A 1 57 ? -4.348 -15.691 -19.949 1.00 60.25 ? 57 ARG A N 1 ATOM 426 C CA . ARG A 1 57 ? -3.334 -16.505 -20.589 1.00 59.17 ? 57 ARG A CA 1 ATOM 427 C C . ARG A 1 57 ? -3.302 -16.166 -22.090 1.00 61.47 ? 57 ARG A C 1 ATOM 428 O O . ARG A 1 57 ? -4.307 -15.733 -22.634 1.00 63.10 ? 57 ARG A O 1 ATOM 429 C CB . ARG A 1 57 ? -3.730 -17.966 -20.336 1.00 59.31 ? 57 ARG A CB 1 ATOM 430 C CG . ARG A 1 57 ? -2.748 -19.028 -20.734 1.00 75.48 ? 57 ARG A CG 1 ATOM 431 C CD . ARG A 1 57 ? -3.335 -20.387 -20.406 1.00 86.17 ? 57 ARG A CD 1 ATOM 432 N NE . ARG A 1 57 ? -3.031 -20.816 -19.040 1.00 90.26 ? 57 ARG A NE 1 ATOM 433 C CZ . ARG A 1 57 ? -3.343 -22.011 -18.542 1.00 97.75 ? 57 ARG A CZ 1 ATOM 434 N NH1 . ARG A 1 57 ? -4.009 -22.894 -19.279 1.00 79.37 ? 57 ARG A NH1 1 ATOM 435 N NH2 . ARG A 1 57 ? -3.005 -22.328 -17.300 1.00 78.65 ? 57 ARG A NH2 1 ATOM 436 N N . LYS A 1 58 ? -2.141 -16.304 -22.730 1.00 54.47 ? 58 LYS A N 1 ATOM 437 C CA . LYS A 1 58 ? -1.902 -16.036 -24.139 1.00 52.68 ? 58 LYS A CA 1 ATOM 438 C C . LYS A 1 58 ? -1.410 -17.358 -24.746 1.00 60.01 ? 58 LYS A C 1 ATOM 439 O O . LYS A 1 58 ? -0.471 -17.948 -24.213 1.00 62.40 ? 58 LYS A O 1 ATOM 440 C CB . LYS A 1 58 ? -0.829 -14.940 -24.257 1.00 54.05 ? 58 LYS A CB 1 ATOM 441 C CG . LYS A 1 58 ? -0.433 -14.543 -25.687 1.00 67.82 ? 58 LYS A CG 1 ATOM 442 C CD . LYS A 1 58 ? 0.869 -13.745 -25.761 1.00 76.03 ? 58 LYS A CD 1 ATOM 443 C CE . LYS A 1 58 ? 0.732 -12.263 -25.424 1.00 98.91 ? 58 LYS A CE 1 ATOM 444 N NZ . LYS A 1 58 ? 2.053 -11.565 -25.316 1.00 112.75 ? 58 LYS A NZ 1 ATOM 445 N N . TYR A 1 59 ? -2.061 -17.855 -25.825 1.00 55.94 ? 59 TYR A N 1 ATOM 446 C CA . TYR A 1 59 ? -1.678 -19.120 -26.468 1.00 54.12 ? 59 TYR A CA 1 ATOM 447 C C . TYR A 1 59 ? -1.059 -18.944 -27.824 1.00 60.20 ? 59 TYR A C 1 ATOM 448 O O . TYR A 1 59 ? -1.454 -18.061 -28.566 1.00 59.77 ? 59 TYR A O 1 ATOM 449 C CB . TYR A 1 59 ? -2.879 -20.029 -26.669 1.00 53.46 ? 59 TYR A CB 1 ATOM 450 C CG . TYR A 1 59 ? -3.449 -20.642 -25.421 1.00 54.57 ? 59 TYR A CG 1 ATOM 451 C CD1 . TYR A 1 59 ? -2.994 -21.873 -24.955 1.00 55.48 ? 59 TYR A CD1 1 ATOM 452 C CD2 . TYR A 1 59 ? -4.560 -20.084 -24.802 1.00 55.74 ? 59 TYR A CD2 1 ATOM 453 C CE1 . TYR A 1 59 ? -3.610 -22.506 -23.878 1.00 54.31 ? 59 TYR A CE1 1 ATOM 454 C CE2 . TYR A 1 59 ? -5.192 -20.714 -23.733 1.00 55.92 ? 59 TYR A CE2 1 ATOM 455 C CZ . TYR A 1 59 ? -4.711 -21.915 -23.267 1.00 57.91 ? 59 TYR A CZ 1 ATOM 456 O OH . TYR A 1 59 ? -5.332 -22.454 -22.170 1.00 57.18 ? 59 TYR A OH 1 ATOM 457 N N . CYS A 1 60 ? -0.160 -19.852 -28.190 1.00 59.86 ? 60 CYS A N 1 ATOM 458 C CA . CYS A 1 60 ? 0.439 -19.867 -29.507 1.00 60.93 ? 60 CYS A CA 1 ATOM 459 C C . CYS A 1 60 ? -0.369 -20.794 -30.367 1.00 62.13 ? 60 CYS A C 1 ATOM 460 O O . CYS A 1 60 ? -0.629 -21.942 -29.983 1.00 61.01 ? 60 CYS A O 1 ATOM 461 C CB . CYS A 1 60 ? 1.898 -20.289 -29.471 1.00 63.37 ? 60 CYS A CB 1 ATOM 462 S SG . CYS A 1 60 ? 2.750 -19.996 -31.032 1.00 69.16 ? 60 CYS A SG 1 ATOM 463 N N . ILE A 1 61 ? -0.796 -20.276 -31.533 1.00 56.99 ? 61 ILE A N 1 ATOM 464 C CA . ILE A 1 61 ? -1.620 -20.994 -32.511 1.00 53.46 ? 61 ILE A CA 1 ATOM 465 C C . ILE A 1 61 ? -0.837 -21.288 -33.799 1.00 53.36 ? 61 ILE A C 1 ATOM 466 O O . ILE A 1 61 ? -1.201 -22.200 -34.513 1.00 50.53 ? 61 ILE A O 1 ATOM 467 C CB . ILE A 1 61 ? -2.988 -20.304 -32.750 1.00 54.34 ? 61 ILE A CB 1 ATOM 468 C CG1 . ILE A 1 61 ? -2.857 -18.890 -33.267 1.00 53.09 ? 61 ILE A CG1 1 ATOM 469 C CG2 . ILE A 1 61 ? -3.820 -20.338 -31.483 1.00 53.71 ? 61 ILE A CG2 1 ATOM 470 C CD1 . ILE A 1 61 ? -3.604 -18.679 -34.410 1.00 48.26 ? 61 ILE A CD1 1 ATOM 471 N N . GLU A 1 62 ? 0.254 -20.571 -34.044 1.00 51.43 ? 62 GLU A N 1 ATOM 472 C CA . GLU A 1 62 ? 1.106 -20.804 -35.212 1.00 53.76 ? 62 GLU A CA 1 ATOM 473 C C . GLU A 1 62 ? 2.546 -20.601 -34.810 1.00 59.50 ? 62 GLU A C 1 ATOM 474 O O . GLU A 1 62 ? 2.880 -19.535 -34.302 1.00 61.01 ? 62 GLU A O 1 ATOM 475 C CB . GLU A 1 62 ? 0.737 -19.885 -36.400 1.00 55.51 ? 62 GLU A CB 1 ATOM 476 C CG . GLU A 1 62 ? 1.486 -20.213 -37.678 1.00 68.30 ? 62 GLU A CG 1 ATOM 477 C CD . GLU A 1 62 ? 1.042 -19.481 -38.933 1.00 100.70 ? 62 GLU A CD 1 ATOM 478 O OE1 . GLU A 1 62 ? -0.079 -18.920 -38.948 1.00 89.08 ? 62 GLU A OE1 1 ATOM 479 O OE2 . GLU A 1 62 ? 1.814 -19.500 -39.921 1.00 100.08 ? 62 GLU A OE2 1 ATOM 480 N N . ALA A 1 63 ? 3.397 -21.615 -35.033 1.00 53.92 ? 63 ALA A N 1 ATOM 481 C CA . ALA A 1 63 ? 4.786 -21.542 -34.639 1.00 52.97 ? 63 ALA A CA 1 ATOM 482 C C . ALA A 1 63 ? 5.761 -21.792 -35.769 1.00 60.28 ? 63 ALA A C 1 ATOM 483 O O . ALA A 1 63 ? 5.373 -22.200 -36.874 1.00 59.94 ? 63 ALA A O 1 ATOM 484 C CB . ALA A 1 63 ? 5.047 -22.488 -33.493 1.00 53.19 ? 63 ALA A CB 1 ATOM 485 N N . LYS A 1 64 ? 7.039 -21.508 -35.489 1.00 59.62 ? 64 LYS A N 1 ATOM 486 C CA . LYS A 1 64 ? 8.130 -21.657 -36.434 1.00 61.19 ? 64 LYS A CA 1 ATOM 487 C C . LYS A 1 64 ? 9.372 -22.235 -35.731 1.00 68.57 ? 64 LYS A C 1 ATOM 488 O O . LYS A 1 64 ? 9.799 -21.697 -34.698 1.00 68.76 ? 64 LYS A O 1 ATOM 489 C CB . LYS A 1 64 ? 8.467 -20.309 -37.091 1.00 62.50 ? 64 LYS A CB 1 ATOM 490 C CG . LYS A 1 64 ? 9.128 -20.476 -38.453 1.00 77.23 ? 64 LYS A CG 1 ATOM 491 C CD . LYS A 1 64 ? 9.332 -19.146 -39.175 1.00 96.02 ? 64 LYS A CD 1 ATOM 492 C CE . LYS A 1 64 ? 10.672 -18.457 -38.971 1.00 108.48 ? 64 LYS A CE 1 ATOM 493 N NZ . LYS A 1 64 ? 10.904 -18.015 -37.565 1.00 113.36 ? 64 LYS A NZ 1 ATOM 494 N N . LEU A 1 65 ? 9.943 -23.331 -36.291 1.00 64.68 ? 65 LEU A N 1 ATOM 495 C CA . LEU A 1 65 ? 11.143 -23.915 -35.736 1.00 64.65 ? 65 LEU A CA 1 ATOM 496 C C . LEU A 1 65 ? 12.290 -23.555 -36.621 1.00 73.94 ? 65 LEU A C 1 ATOM 497 O O . LEU A 1 65 ? 12.260 -23.834 -37.814 1.00 73.74 ? 65 LEU A O 1 ATOM 498 C CB . LEU A 1 65 ? 11.058 -25.428 -35.585 1.00 64.10 ? 65 LEU A CB 1 ATOM 499 C CG . LEU A 1 65 ? 10.139 -25.994 -34.502 1.00 68.23 ? 65 LEU A CG 1 ATOM 500 C CD1 . LEU A 1 65 ? 9.988 -27.490 -34.668 1.00 67.77 ? 65 LEU A CD1 1 ATOM 501 C CD2 . LEU A 1 65 ? 10.627 -25.641 -33.089 1.00 69.75 ? 65 LEU A CD2 1 ATOM 502 N N . THR A 1 66 ? 13.295 -22.902 -36.031 1.00 74.78 ? 66 THR A N 1 ATOM 503 C CA . THR A 1 66 ? 14.537 -22.438 -36.666 1.00 75.16 ? 66 THR A CA 1 ATOM 504 C C . THR A 1 66 ? 15.724 -22.960 -35.861 1.00 79.25 ? 66 THR A C 1 ATOM 505 O O . THR A 1 66 ? 15.538 -23.679 -34.872 1.00 79.56 ? 66 THR A O 1 ATOM 506 C CB . THR A 1 66 ? 14.562 -20.892 -36.680 1.00 87.26 ? 66 THR A CB 1 ATOM 507 O OG1 . THR A 1 66 ? 14.305 -20.376 -35.361 1.00 91.16 ? 66 THR A OG1 1 ATOM 508 C CG2 . THR A 1 66 ? 13.598 -20.306 -37.677 1.00 83.91 ? 66 THR A CG2 1 ATOM 509 N N . ASN A 1 67 ? 16.941 -22.596 -36.287 1.00 75.85 ? 67 ASN A N 1 ATOM 510 C CA . ASN A 1 67 ? 18.194 -22.912 -35.611 1.00 76.21 ? 67 ASN A CA 1 ATOM 511 C C . ASN A 1 67 ? 18.354 -24.388 -35.184 1.00 79.91 ? 67 ASN A C 1 ATOM 512 O O . ASN A 1 67 ? 18.911 -24.639 -34.112 1.00 80.94 ? 67 ASN A O 1 ATOM 513 C CB . ASN A 1 67 ? 18.369 -21.969 -34.403 1.00 78.42 ? 67 ASN A CB 1 ATOM 514 C CG . ASN A 1 67 ? 18.389 -20.513 -34.783 1.00 110.77 ? 67 ASN A CG 1 ATOM 515 O OD1 . ASN A 1 67 ? 17.342 -19.894 -35.009 1.00 95.83 ? 67 ASN A OD1 1 ATOM 516 N ND2 . ASN A 1 67 ? 19.617 -19.993 -34.839 1.00 117.97 ? 67 ASN A ND2 1 ATOM 517 N N . THR A 1 68 ? 17.873 -25.355 -35.997 1.00 74.04 ? 68 THR A N 1 ATOM 518 C CA . THR A 1 68 ? 17.986 -26.773 -35.655 1.00 73.03 ? 68 THR A CA 1 ATOM 519 C C . THR A 1 68 ? 19.445 -27.183 -35.595 1.00 75.82 ? 68 THR A C 1 ATOM 520 O O . THR A 1 68 ? 20.175 -27.040 -36.573 1.00 75.12 ? 68 THR A O 1 ATOM 521 C CB . THR A 1 68 ? 17.125 -27.642 -36.566 1.00 83.02 ? 68 THR A CB 1 ATOM 522 O OG1 . THR A 1 68 ? 15.767 -27.302 -36.345 1.00 83.60 ? 68 THR A OG1 1 ATOM 523 C CG2 . THR A 1 68 ? 17.302 -29.129 -36.301 1.00 80.64 ? 68 THR A CG2 1 ATOM 524 N N . THR A 1 69 ? 19.859 -27.653 -34.404 1.00 72.57 ? 69 THR A N 1 ATOM 525 C CA . THR A 1 69 ? 21.226 -28.066 -34.050 1.00 71.23 ? 69 THR A CA 1 ATOM 526 C C . THR A 1 69 ? 21.266 -29.456 -33.391 1.00 69.43 ? 69 THR A C 1 ATOM 527 O O . THR A 1 69 ? 20.490 -29.729 -32.479 1.00 68.37 ? 69 THR A O 1 ATOM 528 C CB . THR A 1 69 ? 21.878 -26.987 -33.153 1.00 81.80 ? 69 THR A CB 1 ATOM 529 O OG1 . THR A 1 69 ? 21.054 -26.748 -32.006 1.00 73.70 ? 69 THR A OG1 1 ATOM 530 C CG2 . THR A 1 69 ? 22.140 -25.673 -33.905 1.00 85.84 ? 69 THR A CG2 1 ATOM 531 N N . THR A 1 70 ? 22.169 -30.324 -33.855 1.00 63.69 ? 70 THR A N 1 ATOM 532 C CA . THR A 1 70 ? 22.331 -31.669 -33.309 1.00 63.01 ? 70 THR A CA 1 ATOM 533 C C . THR A 1 70 ? 23.769 -32.029 -32.861 1.00 67.53 ? 70 THR A C 1 ATOM 534 O O . THR A 1 70 ? 24.728 -31.862 -33.633 1.00 67.84 ? 70 THR A O 1 ATOM 535 C CB . THR A 1 70 ? 21.811 -32.683 -34.300 1.00 64.43 ? 70 THR A CB 1 ATOM 536 O OG1 . THR A 1 70 ? 20.414 -32.476 -34.488 1.00 72.39 ? 70 THR A OG1 1 ATOM 537 C CG2 . THR A 1 70 ? 22.072 -34.098 -33.867 1.00 54.22 ? 70 THR A CG2 1 ATOM 538 N N . GLU A 1 71 ? 23.897 -32.553 -31.627 1.00 62.91 ? 71 GLU A N 1 ATOM 539 C CA . GLU A 1 71 ? 25.156 -33.074 -31.119 1.00 62.66 ? 71 GLU A CA 1 ATOM 540 C C . GLU A 1 71 ? 25.021 -34.558 -30.873 1.00 67.25 ? 71 GLU A C 1 ATOM 541 O O . GLU A 1 71 ? 24.071 -35.016 -30.233 1.00 67.46 ? 71 GLU A O 1 ATOM 542 C CB . GLU A 1 71 ? 25.658 -32.357 -29.864 1.00 64.29 ? 71 GLU A CB 1 ATOM 543 C CG . GLU A 1 71 ? 27.124 -32.644 -29.563 1.00 78.74 ? 71 GLU A CG 1 ATOM 544 C CD . GLU A 1 71 ? 27.689 -31.942 -28.345 1.00 123.30 ? 71 GLU A CD 1 ATOM 545 O OE1 . GLU A 1 71 ? 28.056 -30.751 -28.470 1.00 133.93 ? 71 GLU A OE1 1 ATOM 546 O OE2 . GLU A 1 71 ? 27.791 -32.587 -27.274 1.00 124.26 ? 71 GLU A OE2 1 ATOM 547 N N . SER A 1 72 ? 25.973 -35.317 -31.400 1.00 64.52 ? 72 SER A N 1 ATOM 548 C CA . SER A 1 72 ? 26.012 -36.763 -31.233 1.00 64.50 ? 72 SER A CA 1 ATOM 549 C C . SER A 1 72 ? 27.285 -37.198 -30.490 1.00 66.80 ? 72 SER A C 1 ATOM 550 O O . SER A 1 72 ? 28.181 -36.381 -30.199 1.00 64.98 ? 72 SER A O 1 ATOM 551 C CB . SER A 1 72 ? 25.868 -37.465 -32.579 1.00 69.38 ? 72 SER A CB 1 ATOM 552 O OG . SER A 1 72 ? 26.717 -36.857 -33.538 1.00 86.93 ? 72 SER A OG 1 ATOM 553 N N . ARG A 1 73 ? 27.302 -38.478 -30.104 1.00 63.15 ? 73 ARG A N 1 ATOM 554 C CA . ARG A 1 73 ? 28.403 -39.137 -29.410 1.00 62.32 ? 73 ARG A CA 1 ATOM 555 C C . ARG A 1 73 ? 28.490 -40.530 -29.963 1.00 64.33 ? 73 ARG A C 1 ATOM 556 O O . ARG A 1 73 ? 27.475 -41.117 -30.356 1.00 60.26 ? 73 ARG A O 1 ATOM 557 C CB . ARG A 1 73 ? 28.181 -39.194 -27.878 1.00 61.87 ? 73 ARG A CB 1 ATOM 558 C CG . ARG A 1 73 ? 28.335 -37.863 -27.132 1.00 65.45 ? 73 ARG A CG 1 ATOM 559 C CD . ARG A 1 73 ? 29.754 -37.547 -26.710 1.00 77.47 ? 73 ARG A CD 1 ATOM 560 N NE . ARG A 1 73 ? 29.827 -36.402 -25.798 1.00 94.09 ? 73 ARG A NE 1 ATOM 561 C CZ . ARG A 1 73 ? 29.975 -35.134 -26.184 1.00 120.06 ? 73 ARG A CZ 1 ATOM 562 N NH1 . ARG A 1 73 ? 30.062 -34.828 -27.477 1.00 108.13 ? 73 ARG A NH1 1 ATOM 563 N NH2 . ARG A 1 73 ? 30.025 -34.161 -25.281 1.00 111.17 ? 73 ARG A NH2 1 ATOM 564 N N . CYS A 1 74 ? 29.714 -41.049 -30.038 1.00 64.94 ? 74 CYS A N 1 ATOM 565 C CA . CYS A 1 74 ? 29.916 -42.402 -30.514 1.00 66.37 ? 74 CYS A CA 1 ATOM 566 C C . CYS A 1 74 ? 29.554 -43.345 -29.379 1.00 67.84 ? 74 CYS A C 1 ATOM 567 O O . CYS A 1 74 ? 29.496 -42.874 -28.236 1.00 69.26 ? 74 CYS A O 1 ATOM 568 C CB . CYS A 1 74 ? 31.350 -42.597 -30.978 1.00 68.10 ? 74 CYS A CB 1 ATOM 569 S SG . CYS A 1 74 ? 31.585 -42.229 -32.723 1.00 73.36 ? 74 CYS A SG 1 ATOM 570 N N . PRO A 1 75 ? 29.259 -44.651 -29.616 1.00 58.17 ? 75 PRO A N 1 ATOM 571 C CA . PRO A 1 75 ? 28.959 -45.519 -28.487 1.00 57.01 ? 75 PRO A CA 1 ATOM 572 C C . PRO A 1 75 ? 30.122 -45.472 -27.481 1.00 63.19 ? 75 PRO A C 1 ATOM 573 O O . PRO A 1 75 ? 31.283 -45.293 -27.888 1.00 63.79 ? 75 PRO A O 1 ATOM 574 C CB . PRO A 1 75 ? 28.827 -46.881 -29.142 1.00 57.76 ? 75 PRO A CB 1 ATOM 575 C CG . PRO A 1 75 ? 28.489 -46.597 -30.521 1.00 61.02 ? 75 PRO A CG 1 ATOM 576 C CD . PRO A 1 75 ? 29.272 -45.418 -30.869 1.00 57.04 ? 75 PRO A CD 1 ATOM 577 N N . THR A 1 76 ? 29.802 -45.557 -26.163 1.00 59.33 ? 76 THR A N 1 ATOM 578 C CA . THR A 1 76 ? 30.764 -45.553 -25.040 1.00 58.44 ? 76 THR A CA 1 ATOM 579 C C . THR A 1 76 ? 31.410 -44.184 -24.801 1.00 64.88 ? 76 THR A C 1 ATOM 580 O O . THR A 1 76 ? 32.211 -44.073 -23.873 1.00 64.34 ? 76 THR A O 1 ATOM 581 C CB . THR A 1 76 ? 31.864 -46.681 -25.146 1.00 51.86 ? 76 THR A CB 1 ATOM 582 O OG1 . THR A 1 76 ? 32.996 -46.214 -25.856 1.00 37.91 ? 76 THR A OG1 1 ATOM 583 C CG2 . THR A 1 76 ? 31.371 -48.008 -25.771 1.00 50.02 ? 76 THR A CG2 1 ATOM 584 N N . GLN A 1 77 ? 31.104 -43.162 -25.633 1.00 63.55 ? 77 GLN A N 1 ATOM 585 C CA . GLN A 1 77 ? 31.708 -41.824 -25.497 1.00 64.49 ? 77 GLN A CA 1 ATOM 586 C C . GLN A 1 77 ? 30.909 -40.860 -24.604 1.00 70.10 ? 77 GLN A C 1 ATOM 587 O O . GLN A 1 77 ? 31.233 -39.672 -24.539 1.00 70.93 ? 77 GLN A O 1 ATOM 588 C CB . GLN A 1 77 ? 31.982 -41.172 -26.878 1.00 66.13 ? 77 GLN A CB 1 ATOM 589 C CG . GLN A 1 77 ? 32.747 -42.038 -27.866 1.00 93.03 ? 77 GLN A CG 1 ATOM 590 C CD . GLN A 1 77 ? 34.238 -42.117 -27.623 1.00 116.16 ? 77 GLN A CD 1 ATOM 591 O OE1 . GLN A 1 77 ? 34.908 -41.129 -27.281 1.00 109.76 ? 77 GLN A OE1 1 ATOM 592 N NE2 . GLN A 1 77 ? 34.802 -43.299 -27.860 1.00 109.90 ? 77 GLN A NE2 1 ATOM 593 N N . GLY A 1 78 ? 29.871 -41.355 -23.950 1.00 67.38 ? 78 GLY A N 1 ATOM 594 C CA . GLY A 1 78 ? 29.034 -40.514 -23.097 1.00 67.61 ? 78 GLY A CA 1 ATOM 595 C C . GLY A 1 78 ? 27.751 -40.010 -23.739 1.00 70.42 ? 78 GLY A C 1 ATOM 596 O O . GLY A 1 78 ? 27.391 -40.448 -24.840 1.00 69.91 ? 78 GLY A O 1 ATOM 597 N N . GLU A 1 79 ? 27.039 -39.108 -23.017 1.00 65.82 ? 79 GLU A N 1 ATOM 598 C CA . GLU A 1 79 ? 25.778 -38.475 -23.424 1.00 65.48 ? 79 GLU A CA 1 ATOM 599 C C . GLU A 1 79 ? 26.100 -37.077 -24.002 1.00 68.56 ? 79 GLU A C 1 ATOM 600 O O . GLU A 1 79 ? 26.931 -36.356 -23.425 1.00 68.99 ? 79 GLU A O 1 ATOM 601 C CB . GLU A 1 79 ? 24.837 -38.345 -22.215 1.00 67.32 ? 79 GLU A CB 1 ATOM 602 C CG . GLU A 1 79 ? 23.358 -38.583 -22.504 1.00 81.85 ? 79 GLU A CG 1 ATOM 603 C CD . GLU A 1 79 ? 22.402 -38.231 -21.372 1.00 100.21 ? 79 GLU A CD 1 ATOM 604 O OE1 . GLU A 1 79 ? 22.657 -37.236 -20.652 1.00 84.61 ? 79 GLU A OE1 1 ATOM 605 O OE2 . GLU A 1 79 ? 21.377 -38.937 -21.225 1.00 101.33 ? 79 GLU A OE2 1 ATOM 606 N N . PRO A 1 80 ? 25.512 -36.683 -25.154 1.00 63.00 ? 80 PRO A N 1 ATOM 607 C CA . PRO A 1 80 ? 25.846 -35.365 -25.713 1.00 62.27 ? 80 PRO A CA 1 ATOM 608 C C . PRO A 1 80 ? 25.073 -34.239 -25.054 1.00 67.95 ? 80 PRO A C 1 ATOM 609 O O . PRO A 1 80 ? 24.065 -34.478 -24.380 1.00 67.30 ? 80 PRO A O 1 ATOM 610 C CB . PRO A 1 80 ? 25.532 -35.510 -27.194 1.00 64.12 ? 80 PRO A CB 1 ATOM 611 C CG . PRO A 1 80 ? 24.584 -36.665 -27.288 1.00 69.30 ? 80 PRO A CG 1 ATOM 612 C CD . PRO A 1 80 ? 24.509 -37.385 -25.974 1.00 64.73 ? 80 PRO A CD 1 ATOM 613 N N . SER A 1 81 ? 25.571 -33.006 -25.209 1.00 66.48 ? 81 SER A N 1 ATOM 614 C CA . SER A 1 81 ? 24.948 -31.839 -24.579 1.00 66.52 ? 81 SER A CA 1 ATOM 615 C C . SER A 1 81 ? 25.109 -30.550 -25.377 1.00 73.36 ? 81 SER A C 1 ATOM 616 O O . SER A 1 81 ? 26.178 -30.308 -25.954 1.00 74.64 ? 81 SER A O 1 ATOM 617 C CB . SER A 1 81 ? 25.519 -31.625 -23.182 1.00 65.83 ? 81 SER A CB 1 ATOM 618 O OG . SER A 1 81 ? 26.757 -30.935 -23.246 1.00 61.45 ? 81 SER A OG 1 ATOM 619 N N . LEU A 1 82 ? 24.060 -29.709 -25.361 1.00 68.90 ? 82 LEU A N 1 ATOM 620 C CA . LEU A 1 82 ? 24.060 -28.398 -25.991 1.00 68.48 ? 82 LEU A CA 1 ATOM 621 C C . LEU A 1 82 ? 23.686 -27.407 -24.907 1.00 72.62 ? 82 LEU A C 1 ATOM 622 O O . LEU A 1 82 ? 23.095 -27.805 -23.902 1.00 72.25 ? 82 LEU A O 1 ATOM 623 C CB . LEU A 1 82 ? 23.052 -28.341 -27.166 1.00 68.65 ? 82 LEU A CB 1 ATOM 624 C CG . LEU A 1 82 ? 23.246 -29.325 -28.339 1.00 72.88 ? 82 LEU A CG 1 ATOM 625 C CD1 . LEU A 1 82 ? 22.058 -29.301 -29.291 1.00 72.89 ? 82 LEU A CD1 1 ATOM 626 C CD2 . LEU A 1 82 ? 24.489 -29.023 -29.108 1.00 73.79 ? 82 LEU A CD2 1 ATOM 627 N N . ASN A 1 83 ? 24.054 -26.130 -25.078 1.00 70.40 ? 83 ASN A N 1 ATOM 628 C CA . ASN A 1 83 ? 23.713 -25.064 -24.115 1.00 70.90 ? 83 ASN A CA 1 ATOM 629 C C . ASN A 1 83 ? 22.198 -24.837 -24.146 1.00 73.53 ? 83 ASN A C 1 ATOM 630 O O . ASN A 1 83 ? 21.594 -24.612 -23.108 1.00 70.73 ? 83 ASN A O 1 ATOM 631 C CB . ASN A 1 83 ? 24.452 -23.756 -24.446 1.00 74.45 ? 83 ASN A CB 1 ATOM 632 C CG . ASN A 1 83 ? 25.927 -23.969 -24.681 1.00 106.30 ? 83 ASN A CG 1 ATOM 633 O OD1 . ASN A 1 83 ? 26.726 -23.974 -23.733 1.00 99.64 ? 83 ASN A OD1 1 ATOM 634 N ND2 . ASN A 1 83 ? 26.301 -24.242 -25.942 1.00 96.32 ? 83 ASN A ND2 1 ATOM 635 N N . GLU A 1 84 ? 21.593 -24.980 -25.350 1.00 70.73 ? 84 GLU A N 1 ATOM 636 C CA . GLU A 1 84 ? 20.171 -24.842 -25.691 1.00 70.67 ? 84 GLU A CA 1 ATOM 637 C C . GLU A 1 84 ? 19.273 -25.582 -24.736 1.00 75.45 ? 84 GLU A C 1 ATOM 638 O O . GLU A 1 84 ? 18.104 -25.216 -24.579 1.00 75.59 ? 84 GLU A O 1 ATOM 639 C CB . GLU A 1 84 ? 19.922 -25.315 -27.131 1.00 71.92 ? 84 GLU A CB 1 ATOM 640 C CG . GLU A 1 84 ? 20.446 -24.372 -28.201 1.00 81.31 ? 84 GLU A CG 1 ATOM 641 C CD . GLU A 1 84 ? 21.949 -24.185 -28.210 1.00 97.71 ? 84 GLU A CD 1 ATOM 642 O OE1 . GLU A 1 84 ? 22.446 -23.344 -27.428 1.00 83.40 ? 84 GLU A OE1 1 ATOM 643 O OE2 . GLU A 1 84 ? 22.637 -24.947 -28.926 1.00 96.81 ? 84 GLU A OE2 1 ATOM 644 N N . GLU A 1 85 ? 19.823 -26.621 -24.093 1.00 71.62 ? 85 GLU A N 1 ATOM 645 C CA . GLU A 1 85 ? 19.135 -27.395 -23.076 1.00 71.21 ? 85 GLU A CA 1 ATOM 646 C C . GLU A 1 85 ? 18.785 -26.463 -21.912 1.00 77.49 ? 85 GLU A C 1 ATOM 647 O O . GLU A 1 85 ? 17.635 -26.476 -21.486 1.00 76.64 ? 85 GLU A O 1 ATOM 648 C CB . GLU A 1 85 ? 19.985 -28.582 -22.645 1.00 72.05 ? 85 GLU A CB 1 ATOM 649 C CG . GLU A 1 85 ? 20.262 -29.543 -23.785 1.00 77.81 ? 85 GLU A CG 1 ATOM 650 C CD . GLU A 1 85 ? 21.033 -30.775 -23.363 1.00 91.56 ? 85 GLU A CD 1 ATOM 651 O OE1 . GLU A 1 85 ? 22.263 -30.665 -23.156 1.00 80.58 ? 85 GLU A OE1 1 ATOM 652 O OE2 . GLU A 1 85 ? 20.396 -31.836 -23.177 1.00 78.11 ? 85 GLU A OE2 1 ATOM 653 N N . GLN A 1 86 ? 19.737 -25.563 -21.506 1.00 77.49 ? 86 GLN A N 1 ATOM 654 C CA . GLN A 1 86 ? 19.602 -24.487 -20.472 1.00 78.67 ? 86 GLN A CA 1 ATOM 655 C C . GLN A 1 86 ? 18.707 -23.329 -20.998 1.00 83.50 ? 86 GLN A C 1 ATOM 656 O O . GLN A 1 86 ? 17.785 -22.915 -20.283 1.00 82.96 ? 86 GLN A O 1 ATOM 657 C CB . GLN A 1 86 ? 20.976 -23.894 -20.014 1.00 79.81 ? 86 GLN A CB 1 ATOM 658 C CG . GLN A 1 86 ? 22.135 -24.889 -19.846 1.00 91.32 ? 86 GLN A CG 1 ATOM 659 C CD . GLN A 1 86 ? 21.793 -26.020 -18.910 1.00 107.68 ? 86 GLN A CD 1 ATOM 660 O OE1 . GLN A 1 86 ? 21.454 -25.796 -17.743 1.00 105.91 ? 86 GLN A OE1 1 ATOM 661 N NE2 . GLN A 1 86 ? 21.821 -27.254 -19.419 1.00 93.81 ? 86 GLN A NE2 1 ATOM 662 N N . ASP A 1 87 ? 18.993 -22.818 -22.252 1.00 78.68 ? 87 ASP A N 1 ATOM 663 C CA . ASP A 1 87 ? 18.252 -21.762 -22.965 1.00 77.18 ? 87 ASP A CA 1 ATOM 664 C C . ASP A 1 87 ? 16.773 -22.214 -23.082 1.00 80.19 ? 87 ASP A C 1 ATOM 665 O O . ASP A 1 87 ? 16.479 -23.347 -23.494 1.00 79.93 ? 87 ASP A O 1 ATOM 666 C CB . ASP A 1 87 ? 18.890 -21.531 -24.352 1.00 78.48 ? 87 ASP A CB 1 ATOM 667 C CG . ASP A 1 87 ? 18.768 -20.155 -25.010 1.00 79.76 ? 87 ASP A CG 1 ATOM 668 O OD1 . ASP A 1 87 ? 17.708 -19.491 -24.826 1.00 76.17 ? 87 ASP A OD1 1 ATOM 669 O OD2 . ASP A 1 87 ? 19.690 -19.790 -25.807 1.00 82.66 ? 87 ASP A OD2 1 ATOM 670 N N . LYS A 1 88 ? 15.860 -21.357 -22.618 1.00 75.45 ? 88 LYS A N 1 ATOM 671 C CA . LYS A 1 88 ? 14.436 -21.672 -22.563 1.00 74.60 ? 88 LYS A CA 1 ATOM 672 C C . LYS A 1 88 ? 13.669 -21.478 -23.901 1.00 77.61 ? 88 LYS A C 1 ATOM 673 O O . LYS A 1 88 ? 12.561 -22.010 -24.050 1.00 77.34 ? 88 LYS A O 1 ATOM 674 C CB . LYS A 1 88 ? 13.775 -20.884 -21.416 1.00 76.30 ? 88 LYS A CB 1 ATOM 675 C CG . LYS A 1 88 ? 13.472 -21.699 -20.147 1.00 74.81 ? 88 LYS A CG 1 ATOM 676 C CD . LYS A 1 88 ? 12.327 -22.722 -20.335 1.00 83.03 ? 88 LYS A CD 1 ATOM 677 C CE . LYS A 1 88 ? 10.948 -22.104 -20.437 1.00 94.03 ? 88 LYS A CE 1 ATOM 678 N NZ . LYS A 1 88 ? 10.097 -22.790 -21.448 1.00 101.31 ? 88 LYS A NZ 1 ATOM 679 N N . ARG A 1 89 ? 14.273 -20.765 -24.876 1.00 72.64 ? 89 ARG A N 1 ATOM 680 C CA . ARG A 1 89 ? 13.657 -20.503 -26.184 1.00 71.16 ? 89 ARG A CA 1 ATOM 681 C C . ARG A 1 89 ? 13.709 -21.740 -27.065 1.00 74.98 ? 89 ARG A C 1 ATOM 682 O O . ARG A 1 89 ? 12.995 -21.806 -28.081 1.00 74.71 ? 89 ARG A O 1 ATOM 683 C CB . ARG A 1 89 ? 14.332 -19.318 -26.894 1.00 66.78 ? 89 ARG A CB 1 ATOM 684 C CG . ARG A 1 89 ? 14.284 -18.022 -26.095 1.00 69.05 ? 89 ARG A CG 1 ATOM 685 C CD . ARG A 1 89 ? 15.172 -16.939 -26.690 1.00 68.85 ? 89 ARG A CD 1 ATOM 686 N NE . ARG A 1 89 ? 16.604 -17.222 -26.571 1.00 68.02 ? 89 ARG A NE 1 ATOM 687 C CZ . ARG A 1 89 ? 17.537 -16.612 -27.292 1.00 85.75 ? 89 ARG A CZ 1 ATOM 688 N NH1 . ARG A 1 89 ? 17.199 -15.681 -28.177 1.00 76.01 ? 89 ARG A NH1 1 ATOM 689 N NH2 . ARG A 1 89 ? 18.819 -16.927 -27.135 1.00 74.69 ? 89 ARG A NH2 1 ATOM 690 N N . PHE A 1 90 ? 14.559 -22.720 -26.681 1.00 70.08 ? 90 PHE A N 1 ATOM 691 C CA . PHE A 1 90 ? 14.740 -23.938 -27.452 1.00 69.25 ? 90 PHE A CA 1 ATOM 692 C C . PHE A 1 90 ? 14.011 -25.115 -26.861 1.00 71.75 ? 90 PHE A C 1 ATOM 693 O O . PHE A 1 90 ? 13.811 -25.159 -25.649 1.00 71.47 ? 90 PHE A O 1 ATOM 694 C CB . PHE A 1 90 ? 16.227 -24.269 -27.600 1.00 71.12 ? 90 PHE A CB 1 ATOM 695 C CG . PHE A 1 90 ? 17.024 -23.239 -28.360 1.00 72.93 ? 90 PHE A CG 1 ATOM 696 C CD1 . PHE A 1 90 ? 17.584 -22.148 -27.706 1.00 75.64 ? 90 PHE A CD1 1 ATOM 697 C CD2 . PHE A 1 90 ? 17.240 -23.373 -29.724 1.00 76.03 ? 90 PHE A CD2 1 ATOM 698 C CE1 . PHE A 1 90 ? 18.325 -21.194 -28.410 1.00 76.42 ? 90 PHE A CE1 1 ATOM 699 C CE2 . PHE A 1 90 ? 17.980 -22.414 -30.432 1.00 78.55 ? 90 PHE A CE2 1 ATOM 700 C CZ . PHE A 1 90 ? 18.506 -21.326 -29.769 1.00 76.12 ? 90 PHE A CZ 1 ATOM 701 N N . ILE A 1 91 ? 13.593 -26.059 -27.731 1.00 66.76 ? 91 ILE A N 1 ATOM 702 C CA . ILE A 1 91 ? 12.977 -27.323 -27.351 1.00 65.83 ? 91 ILE A CA 1 ATOM 703 C C . ILE A 1 91 ? 13.920 -28.448 -27.806 1.00 68.92 ? 91 ILE A C 1 ATOM 704 O O . ILE A 1 91 ? 14.293 -28.544 -28.986 1.00 65.84 ? 91 ILE A O 1 ATOM 705 C CB . ILE A 1 91 ? 11.492 -27.509 -27.755 1.00 69.16 ? 91 ILE A CB 1 ATOM 706 C CG1 . ILE A 1 91 ? 10.900 -28.815 -27.137 1.00 69.18 ? 91 ILE A CG1 1 ATOM 707 C CG2 . ILE A 1 91 ? 11.297 -27.436 -29.285 1.00 71.25 ? 91 ILE A CG2 1 ATOM 708 C CD1 . ILE A 1 91 ? 9.338 -28.964 -27.075 1.00 71.63 ? 91 ILE A CD1 1 ATOM 709 N N . CYS A 1 92 ? 14.354 -29.254 -26.817 1.00 66.92 ? 92 CYS A N 1 ATOM 710 C CA . CYS A 1 92 ? 15.315 -30.343 -26.991 1.00 65.71 ? 92 CYS A CA 1 ATOM 711 C C . CYS A 1 92 ? 14.751 -31.729 -26.725 1.00 63.89 ? 92 CYS A C 1 ATOM 712 O O . CYS A 1 92 ? 13.749 -31.903 -26.011 1.00 62.63 ? 92 CYS A O 1 ATOM 713 C CB . CYS A 1 92 ? 16.558 -30.091 -26.152 1.00 66.64 ? 92 CYS A CB 1 ATOM 714 S SG . CYS A 1 92 ? 17.283 -28.466 -26.423 1.00 71.87 ? 92 CYS A SG 1 ATOM 715 N N . LYS A 1 93 ? 15.432 -32.718 -27.307 1.00 56.15 ? 93 LYS A N 1 ATOM 716 C CA . LYS A 1 93 ? 15.142 -34.122 -27.148 1.00 54.38 ? 93 LYS A CA 1 ATOM 717 C C . LYS A 1 93 ? 16.413 -34.934 -27.342 1.00 58.28 ? 93 LYS A C 1 ATOM 718 O O . LYS A 1 93 ? 17.155 -34.711 -28.307 1.00 57.88 ? 93 LYS A O 1 ATOM 719 C CB . LYS A 1 93 ? 14.038 -34.565 -28.125 1.00 55.05 ? 93 LYS A CB 1 ATOM 720 C CG . LYS A 1 93 ? 13.806 -36.079 -28.237 1.00 51.41 ? 93 LYS A CG 1 ATOM 721 C CD . LYS A 1 93 ? 12.746 -36.620 -27.291 1.00 47.26 ? 93 LYS A CD 1 ATOM 722 C CE . LYS A 1 93 ? 12.299 -38.021 -27.648 1.00 57.88 ? 93 LYS A CE 1 ATOM 723 N NZ . LYS A 1 93 ? 11.576 -38.089 -28.958 1.00 62.21 ? 93 LYS A NZ 1 ATOM 724 N N . HIS A 1 94 ? 16.638 -35.891 -26.421 1.00 53.75 ? 94 HIS A N 1 ATOM 725 C CA . HIS A 1 94 ? 17.698 -36.884 -26.489 1.00 52.07 ? 94 HIS A CA 1 ATOM 726 C C . HIS A 1 94 ? 17.144 -38.148 -27.124 1.00 56.06 ? 94 HIS A C 1 ATOM 727 O O . HIS A 1 94 ? 16.002 -38.530 -26.855 1.00 55.35 ? 94 HIS A O 1 ATOM 728 C CB . HIS A 1 94 ? 18.185 -37.238 -25.111 1.00 52.17 ? 94 HIS A CB 1 ATOM 729 C CG . HIS A 1 94 ? 19.157 -36.263 -24.567 1.00 56.00 ? 94 HIS A CG 1 ATOM 730 N ND1 . HIS A 1 94 ? 20.521 -36.493 -24.635 1.00 58.34 ? 94 HIS A ND1 1 ATOM 731 C CD2 . HIS A 1 94 ? 18.938 -35.082 -23.947 1.00 57.92 ? 94 HIS A CD2 1 ATOM 732 C CE1 . HIS A 1 94 ? 21.086 -35.450 -24.047 1.00 57.71 ? 94 HIS A CE1 1 ATOM 733 N NE2 . HIS A 1 94 ? 20.169 -34.581 -23.606 1.00 57.78 ? 94 HIS A NE2 1 ATOM 734 N N . SER A 1 95 ? 17.960 -38.805 -27.955 1.00 53.47 ? 95 SER A N 1 ATOM 735 C CA . SER A 1 95 ? 17.612 -40.067 -28.578 1.00 54.06 ? 95 SER A CA 1 ATOM 736 C C . SER A 1 95 ? 18.871 -40.922 -28.786 1.00 61.26 ? 95 SER A C 1 ATOM 737 O O . SER A 1 95 ? 19.933 -40.587 -28.268 1.00 61.39 ? 95 SER A O 1 ATOM 738 C CB . SER A 1 95 ? 16.851 -39.831 -29.873 1.00 58.32 ? 95 SER A CB 1 ATOM 739 O OG . SER A 1 95 ? 15.741 -40.707 -29.959 1.00 74.87 ? 95 SER A OG 1 ATOM 740 N N . MET A 1 96 ? 18.747 -42.027 -29.530 1.00 60.09 ? 96 MET A N 1 ATOM 741 C CA . MET A 1 96 ? 19.812 -43.000 -29.804 1.00 60.35 ? 96 MET A CA 1 ATOM 742 C C . MET A 1 96 ? 19.824 -43.289 -31.281 1.00 60.49 ? 96 MET A C 1 ATOM 743 O O . MET A 1 96 ? 18.781 -43.616 -31.847 1.00 58.97 ? 96 MET A O 1 ATOM 744 C CB . MET A 1 96 ? 19.505 -44.354 -29.096 1.00 63.97 ? 96 MET A CB 1 ATOM 745 C CG . MET A 1 96 ? 19.404 -44.289 -27.606 1.00 69.11 ? 96 MET A CG 1 ATOM 746 S SD . MET A 1 96 ? 20.994 -44.721 -26.945 1.00 75.24 ? 96 MET A SD 1 ATOM 747 C CE . MET A 1 96 ? 21.370 -43.246 -25.870 1.00 71.52 ? 96 MET A CE 1 ATOM 748 N N . VAL A 1 97 ? 20.999 -43.251 -31.895 1.00 56.51 ? 97 VAL A N 1 ATOM 749 C CA . VAL A 1 97 ? 21.165 -43.611 -33.306 1.00 55.87 ? 97 VAL A CA 1 ATOM 750 C C . VAL A 1 97 ? 22.144 -44.781 -33.445 1.00 58.27 ? 97 VAL A C 1 ATOM 751 O O . VAL A 1 97 ? 22.920 -45.060 -32.528 1.00 57.12 ? 97 VAL A O 1 ATOM 752 C CB . VAL A 1 97 ? 21.552 -42.434 -34.236 1.00 59.72 ? 97 VAL A CB 1 ATOM 753 C CG1 . VAL A 1 97 ? 20.454 -41.374 -34.286 1.00 59.41 ? 97 VAL A CG1 1 ATOM 754 C CG2 . VAL A 1 97 ? 22.903 -41.834 -33.844 1.00 59.67 ? 97 VAL A CG2 1 ATOM 755 N N . ASP A 1 98 ? 22.107 -45.459 -34.599 1.00 53.81 ? 98 ASP A N 1 ATOM 756 C CA . ASP A 1 98 ? 23.030 -46.543 -34.890 1.00 52.76 ? 98 ASP A CA 1 ATOM 757 C C . ASP A 1 98 ? 24.352 -45.921 -35.284 1.00 59.90 ? 98 ASP A C 1 ATOM 758 O O . ASP A 1 98 ? 24.427 -45.085 -36.184 1.00 61.03 ? 98 ASP A O 1 ATOM 759 C CB . ASP A 1 98 ? 22.518 -47.425 -36.024 1.00 53.53 ? 98 ASP A CB 1 ATOM 760 C CG . ASP A 1 98 ? 21.365 -48.322 -35.662 1.00 63.54 ? 98 ASP A CG 1 ATOM 761 O OD1 . ASP A 1 98 ? 21.243 -48.674 -34.482 1.00 60.68 ? 98 ASP A OD1 1 ATOM 762 O OD2 . ASP A 1 98 ? 20.608 -48.721 -36.582 1.00 78.38 ? 98 ASP A OD2 1 ATOM 763 N N . ARG A 1 99 ? 25.373 -46.278 -34.559 1.00 57.62 ? 99 ARG A N 1 ATOM 764 C CA . ARG A 1 99 ? 26.720 -45.833 -34.804 1.00 58.39 ? 99 ARG A CA 1 ATOM 765 C C . ARG A 1 99 ? 27.588 -47.048 -35.133 1.00 65.53 ? 99 ARG A C 1 ATOM 766 O O . ARG A 1 99 ? 27.156 -48.187 -34.949 1.00 64.80 ? 99 ARG A O 1 ATOM 767 C CB . ARG A 1 99 ? 27.273 -45.009 -33.627 1.00 56.65 ? 99 ARG A CB 1 ATOM 768 C CG . ARG A 1 99 ? 26.633 -43.633 -33.396 1.00 61.19 ? 99 ARG A CG 1 ATOM 769 C CD . ARG A 1 99 ? 26.573 -42.693 -34.603 1.00 52.06 ? 99 ARG A CD 1 ATOM 770 N NE . ARG A 1 99 ? 27.874 -42.158 -35.045 1.00 31.98 ? 99 ARG A NE 1 ATOM 771 C CZ . ARG A 1 99 ? 28.449 -41.059 -34.548 1.00 54.87 ? 99 ARG A CZ 1 ATOM 772 N NH1 . ARG A 1 99 ? 27.900 -40.416 -33.528 1.00 59.60 ? 99 ARG A NH1 1 ATOM 773 N NH2 . ARG A 1 99 ? 29.604 -40.630 -35.030 1.00 36.57 ? 99 ARG A NH2 1 ATOM 774 N N . GLY A 1 100 ? 28.776 -46.772 -35.666 1.00 65.03 ? 100 GLY A N 1 ATOM 775 C CA . GLY A 1 100 ? 29.749 -47.758 -36.099 1.00 65.83 ? 100 GLY A CA 1 ATOM 776 C C . GLY A 1 100 ? 30.711 -47.197 -37.121 1.00 72.15 ? 100 GLY A C 1 ATOM 777 O O . GLY A 1 100 ? 30.721 -45.985 -37.370 1.00 71.28 ? 100 GLY A O 1 ATOM 778 N N . TRP A 1 101 ? 31.516 -48.092 -37.727 1.00 70.78 ? 101 TRP A N 1 ATOM 779 C CA . TRP A 1 101 ? 32.565 -47.763 -38.690 1.00 71.46 ? 101 TRP A CA 1 ATOM 780 C C . TRP A 1 101 ? 32.173 -46.844 -39.839 1.00 70.28 ? 101 TRP A C 1 ATOM 781 O O . TRP A 1 101 ? 32.895 -45.867 -40.021 1.00 67.75 ? 101 TRP A O 1 ATOM 782 C CB . TRP A 1 101 ? 33.264 -49.008 -39.231 1.00 72.40 ? 101 TRP A CB 1 ATOM 783 C CG . TRP A 1 101 ? 34.034 -49.818 -38.224 1.00 75.54 ? 101 TRP A CG 1 ATOM 784 C CD1 . TRP A 1 101 ? 34.069 -49.651 -36.865 1.00 78.92 ? 101 TRP A CD1 1 ATOM 785 C CD2 . TRP A 1 101 ? 34.803 -50.995 -38.501 1.00 76.33 ? 101 TRP A CD2 1 ATOM 786 N NE1 . TRP A 1 101 ? 34.815 -50.648 -36.282 1.00 79.10 ? 101 TRP A NE1 1 ATOM 787 C CE2 . TRP A 1 101 ? 35.282 -51.486 -37.262 1.00 81.09 ? 101 TRP A CE2 1 ATOM 788 C CE3 . TRP A 1 101 ? 35.159 -51.672 -39.684 1.00 78.05 ? 101 TRP A CE3 1 ATOM 789 C CZ2 . TRP A 1 101 ? 36.122 -52.606 -37.176 1.00 80.83 ? 101 TRP A CZ2 1 ATOM 790 C CZ3 . TRP A 1 101 ? 35.983 -52.782 -39.595 1.00 80.03 ? 101 TRP A CZ3 1 ATOM 791 C CH2 . TRP A 1 101 ? 36.453 -53.242 -38.354 1.00 80.91 ? 101 TRP A CH2 1 ATOM 792 N N . GLY A 1 102 ? 31.085 -47.129 -40.571 1.00 65.74 ? 102 GLY A N 1 ATOM 793 C CA . GLY A 1 102 ? 30.626 -46.383 -41.744 1.00 64.85 ? 102 GLY A CA 1 ATOM 794 C C . GLY A 1 102 ? 29.948 -45.052 -41.482 1.00 65.75 ? 102 GLY A C 1 ATOM 795 O O . GLY A 1 102 ? 29.360 -44.466 -42.398 1.00 65.49 ? 102 GLY A O 1 ATOM 796 N N . ASN A 1 103 ? 30.020 -44.577 -40.217 1.00 59.27 ? 103 ASN A N 1 ATOM 797 C CA . ASN A 1 103 ? 29.471 -43.321 -39.749 1.00 57.41 ? 103 ASN A CA 1 ATOM 798 C C . ASN A 1 103 ? 30.330 -42.726 -38.623 1.00 62.66 ? 103 ASN A C 1 ATOM 799 O O . ASN A 1 103 ? 29.845 -41.947 -37.790 1.00 63.22 ? 103 ASN A O 1 ATOM 800 C CB . ASN A 1 103 ? 27.971 -43.414 -39.410 1.00 53.83 ? 103 ASN A CB 1 ATOM 801 C CG . ASN A 1 103 ? 27.617 -44.327 -38.279 1.00 76.62 ? 103 ASN A CG 1 ATOM 802 O OD1 . ASN A 1 103 ? 27.777 -43.972 -37.117 1.00 66.98 ? 103 ASN A OD1 1 ATOM 803 N ND2 . ASN A 1 103 ? 27.068 -45.502 -38.593 1.00 68.53 ? 103 ASN A ND2 1 ATOM 804 N N . GLY A 1 104 ? 31.615 -43.057 -38.655 1.00 61.25 ? 104 GLY A N 1 ATOM 805 C CA . GLY A 1 104 ? 32.643 -42.470 -37.797 1.00 63.12 ? 104 GLY A CA 1 ATOM 806 C C . GLY A 1 104 ? 33.039 -43.072 -36.462 1.00 71.87 ? 104 GLY A C 1 ATOM 807 O O . GLY A 1 104 ? 33.883 -42.478 -35.776 1.00 73.47 ? 104 GLY A O 1 ATOM 808 N N . CYS A 1 105 ? 32.467 -44.228 -36.066 1.00 69.69 ? 105 CYS A N 1 ATOM 809 C CA . CYS A 1 105 ? 32.794 -44.806 -34.749 1.00 70.89 ? 105 CYS A CA 1 ATOM 810 C C . CYS A 1 105 ? 33.661 -46.039 -34.826 1.00 78.07 ? 105 CYS A C 1 ATOM 811 O O . CYS A 1 105 ? 33.386 -46.925 -35.637 1.00 77.98 ? 105 CYS A O 1 ATOM 812 C CB . CYS A 1 105 ? 31.528 -45.082 -33.933 1.00 70.92 ? 105 CYS A CB 1 ATOM 813 S SG . CYS A 1 105 ? 30.457 -43.638 -33.678 1.00 74.01 ? 105 CYS A SG 1 ATOM 814 N N . GLY A 1 106 ? 34.640 -46.134 -33.924 1.00 75.97 ? 106 GLY A N 1 ATOM 815 C CA . GLY A 1 106 ? 35.504 -47.310 -33.834 1.00 76.58 ? 106 GLY A CA 1 ATOM 816 C C . GLY A 1 106 ? 34.758 -48.555 -33.366 1.00 81.84 ? 106 GLY A C 1 ATOM 817 O O . GLY A 1 106 ? 35.118 -49.684 -33.725 1.00 81.65 ? 106 GLY A O 1 ATOM 818 N N . LEU A 1 107 ? 33.690 -48.341 -32.559 1.00 78.00 ? 107 LEU A N 1 ATOM 819 C CA . LEU A 1 107 ? 32.813 -49.376 -32.003 1.00 76.70 ? 107 LEU A CA 1 ATOM 820 C C . LEU A 1 107 ? 31.445 -49.297 -32.671 1.00 77.49 ? 107 LEU A C 1 ATOM 821 O O . LEU A 1 107 ? 31.068 -48.233 -33.146 1.00 75.92 ? 107 LEU A O 1 ATOM 822 C CB . LEU A 1 107 ? 32.630 -49.175 -30.495 1.00 76.54 ? 107 LEU A CB 1 ATOM 823 C CG . LEU A 1 107 ? 33.869 -49.173 -29.606 1.00 80.33 ? 107 LEU A CG 1 ATOM 824 C CD1 . LEU A 1 107 ? 34.346 -47.742 -29.335 1.00 80.64 ? 107 LEU A CD1 1 ATOM 825 C CD2 . LEU A 1 107 ? 33.552 -49.810 -28.287 1.00 82.54 ? 107 LEU A CD2 1 ATOM 826 N N . PHE A 1 108 ? 30.709 -50.412 -32.690 1.00 73.73 ? 108 PHE A N 1 ATOM 827 C CA . PHE A 1 108 ? 29.373 -50.500 -33.258 1.00 74.55 ? 108 PHE A CA 1 ATOM 828 C C . PHE A 1 108 ? 28.322 -50.551 -32.143 1.00 80.02 ? 108 PHE A C 1 ATOM 829 O O . PHE A 1 108 ? 28.324 -51.476 -31.329 1.00 83.33 ? 108 PHE A O 1 ATOM 830 C CB . PHE A 1 108 ? 29.239 -51.770 -34.090 1.00 77.35 ? 108 PHE A CB 1 ATOM 831 C CG . PHE A 1 108 ? 30.059 -51.838 -35.347 1.00 80.99 ? 108 PHE A CG 1 ATOM 832 C CD1 . PHE A 1 108 ? 29.551 -51.363 -36.554 1.00 85.69 ? 108 PHE A CD1 1 ATOM 833 C CD2 . PHE A 1 108 ? 31.291 -52.480 -35.357 1.00 85.08 ? 108 PHE A CD2 1 ATOM 834 C CE1 . PHE A 1 108 ? 30.284 -51.482 -37.739 1.00 87.32 ? 108 PHE A CE1 1 ATOM 835 C CE2 . PHE A 1 108 ? 32.022 -52.609 -36.544 1.00 88.64 ? 108 PHE A CE2 1 ATOM 836 C CZ . PHE A 1 108 ? 31.511 -52.110 -37.727 1.00 87.04 ? 108 PHE A CZ 1 ATOM 837 N N . GLY A 1 109 ? 27.405 -49.601 -32.138 1.00 73.56 ? 109 GLY A N 1 ATOM 838 C CA . GLY A 1 109 ? 26.344 -49.574 -31.144 1.00 72.59 ? 109 GLY A CA 1 ATOM 839 C C . GLY A 1 109 ? 25.407 -48.391 -31.229 1.00 75.64 ? 109 GLY A C 1 ATOM 840 O O . GLY A 1 109 ? 25.341 -47.722 -32.255 1.00 76.76 ? 109 GLY A O 1 ATOM 841 N N . LYS A 1 110 ? 24.685 -48.119 -30.137 1.00 70.08 ? 110 LYS A N 1 ATOM 842 C CA . LYS A 1 110 ? 23.714 -47.030 -30.083 1.00 68.81 ? 110 LYS A CA 1 ATOM 843 C C . LYS A 1 110 ? 24.334 -45.760 -29.527 1.00 73.35 ? 110 LYS A C 1 ATOM 844 O O . LYS A 1 110 ? 24.523 -45.631 -28.316 1.00 74.59 ? 110 LYS A O 1 ATOM 845 C CB . LYS A 1 110 ? 22.428 -47.449 -29.334 1.00 69.30 ? 110 LYS A CB 1 ATOM 846 C CG . LYS A 1 110 ? 21.679 -48.646 -29.963 1.00 59.31 ? 110 LYS A CG 1 ATOM 847 C CD . LYS A 1 110 ? 20.826 -48.228 -31.139 1.00 59.06 ? 110 LYS A CD 1 ATOM 848 C CE . LYS A 1 110 ? 19.830 -49.307 -31.492 1.00 66.33 ? 110 LYS A CE 1 ATOM 849 N NZ . LYS A 1 110 ? 19.099 -49.016 -32.768 1.00 65.50 ? 110 LYS A NZ 1 ATOM 850 N N . GLY A 1 111 ? 24.694 -44.862 -30.431 1.00 68.71 ? 111 GLY A N 1 ATOM 851 C CA . GLY A 1 111 ? 25.286 -43.580 -30.086 1.00 68.33 ? 111 GLY A CA 1 ATOM 852 C C . GLY A 1 111 ? 24.219 -42.565 -29.746 1.00 72.37 ? 111 GLY A C 1 ATOM 853 O O . GLY A 1 111 ? 23.257 -42.388 -30.494 1.00 72.57 ? 111 GLY A O 1 ATOM 854 N N . GLY A 1 112 ? 24.381 -41.923 -28.598 1.00 68.65 ? 112 GLY A N 1 ATOM 855 C CA . GLY A 1 112 ? 23.460 -40.910 -28.099 1.00 67.67 ? 112 GLY A CA 1 ATOM 856 C C . GLY A 1 112 ? 23.444 -39.655 -28.938 1.00 69.92 ? 112 GLY A C 1 ATOM 857 O O . GLY A 1 112 ? 24.498 -39.157 -29.339 1.00 69.10 ? 112 GLY A O 1 ATOM 858 N N . ILE A 1 113 ? 22.236 -39.159 -29.221 1.00 66.47 ? 113 ILE A N 1 ATOM 859 C CA . ILE A 1 113 ? 21.998 -37.959 -30.017 1.00 66.12 ? 113 ILE A CA 1 ATOM 860 C C . ILE A 1 113 ? 21.172 -36.969 -29.200 1.00 68.68 ? 113 ILE A C 1 ATOM 861 O O . ILE A 1 113 ? 20.492 -37.371 -28.253 1.00 69.14 ? 113 ILE A O 1 ATOM 862 C CB . ILE A 1 113 ? 21.312 -38.349 -31.358 1.00 69.54 ? 113 ILE A CB 1 ATOM 863 C CG1 . ILE A 1 113 ? 21.661 -37.374 -32.469 1.00 71.18 ? 113 ILE A CG1 1 ATOM 864 C CG2 . ILE A 1 113 ? 19.802 -38.541 -31.221 1.00 69.68 ? 113 ILE A CG2 1 ATOM 865 C CD1 . ILE A 1 113 ? 20.844 -37.539 -33.845 1.00 87.92 ? 113 ILE A CD1 1 ATOM 866 N N . VAL A 1 114 ? 21.245 -35.689 -29.557 1.00 63.62 ? 114 VAL A N 1 ATOM 867 C CA . VAL A 1 114 ? 20.466 -34.610 -28.957 1.00 62.99 ? 114 VAL A CA 1 ATOM 868 C C . VAL A 1 114 ? 20.162 -33.547 -30.033 1.00 67.99 ? 114 VAL A C 1 ATOM 869 O O . VAL A 1 114 ? 21.060 -33.119 -30.756 1.00 69.14 ? 114 VAL A O 1 ATOM 870 C CB . VAL A 1 114 ? 21.048 -34.037 -27.628 1.00 66.08 ? 114 VAL A CB 1 ATOM 871 C CG1 . VAL A 1 114 ? 22.420 -33.396 -27.809 1.00 65.56 ? 114 VAL A CG1 1 ATOM 872 C CG2 . VAL A 1 114 ? 20.081 -33.063 -26.970 1.00 65.82 ? 114 VAL A CG2 1 ATOM 873 N N . THR A 1 115 ? 18.883 -33.183 -30.175 1.00 63.19 ? 115 THR A N 1 ATOM 874 C CA . THR A 1 115 ? 18.434 -32.189 -31.142 1.00 61.92 ? 115 THR A CA 1 ATOM 875 C C . THR A 1 115 ? 17.695 -31.051 -30.417 1.00 65.79 ? 115 THR A C 1 ATOM 876 O O . THR A 1 115 ? 16.808 -31.324 -29.596 1.00 64.20 ? 115 THR A O 1 ATOM 877 C CB . THR A 1 115 ? 17.559 -32.859 -32.225 1.00 65.07 ? 115 THR A CB 1 ATOM 878 O OG1 . THR A 1 115 ? 18.128 -34.099 -32.645 1.00 55.46 ? 115 THR A OG1 1 ATOM 879 C CG2 . THR A 1 115 ? 17.311 -31.963 -33.420 1.00 66.46 ? 115 THR A CG2 1 ATOM 880 N N . CYS A 1 116 ? 18.067 -29.779 -30.734 1.00 64.24 ? 116 CYS A N 1 ATOM 881 C CA . CYS A 1 116 ? 17.451 -28.543 -30.215 1.00 65.47 ? 116 CYS A CA 1 ATOM 882 C C . CYS A 1 116 ? 17.070 -27.642 -31.349 1.00 68.09 ? 116 CYS A C 1 ATOM 883 O O . CYS A 1 116 ? 17.807 -27.553 -32.329 1.00 66.90 ? 116 CYS A O 1 ATOM 884 C CB . CYS A 1 116 ? 18.360 -27.815 -29.236 1.00 67.24 ? 116 CYS A CB 1 ATOM 885 S SG . CYS A 1 116 ? 18.792 -28.777 -27.763 1.00 72.20 ? 116 CYS A SG 1 ATOM 886 N N . ALA A 1 117 ? 15.930 -26.950 -31.210 1.00 65.42 ? 117 ALA A N 1 ATOM 887 C CA . ALA A 1 117 ? 15.428 -26.012 -32.223 1.00 65.52 ? 117 ALA A CA 1 ATOM 888 C C . ALA A 1 117 ? 14.758 -24.842 -31.537 1.00 68.94 ? 117 ALA A C 1 ATOM 889 O O . ALA A 1 117 ? 14.255 -25.004 -30.411 1.00 67.57 ? 117 ALA A O 1 ATOM 890 C CB . ALA A 1 117 ? 14.455 -26.705 -33.163 1.00 66.28 ? 117 ALA A CB 1 ATOM 891 N N . LYS A 1 118 ? 14.797 -23.649 -32.197 1.00 65.08 ? 118 LYS A N 1 ATOM 892 C CA . LYS A 1 118 ? 14.245 -22.413 -31.641 1.00 63.78 ? 118 LYS A CA 1 ATOM 893 C C . LYS A 1 118 ? 12.786 -22.239 -31.964 1.00 64.75 ? 118 LYS A C 1 ATOM 894 O O . LYS A 1 118 ? 12.427 -22.070 -33.142 1.00 63.12 ? 118 LYS A O 1 ATOM 895 C CB . LYS A 1 118 ? 15.066 -21.180 -32.042 1.00 65.21 ? 118 LYS A CB 1 ATOM 896 C CG . LYS A 1 118 ? 15.073 -20.114 -30.954 1.00 74.32 ? 118 LYS A CG 1 ATOM 897 C CD . LYS A 1 118 ? 15.535 -18.771 -31.481 1.00 83.82 ? 118 LYS A CD 1 ATOM 898 C CE . LYS A 1 118 ? 15.270 -17.678 -30.478 1.00 99.25 ? 118 LYS A CE 1 ATOM 899 N NZ . LYS A 1 118 ? 15.744 -16.358 -30.974 1.00 117.99 ? 118 LYS A NZ 1 ATOM 900 N N . PHE A 1 119 ? 11.945 -22.267 -30.893 1.00 60.04 ? 119 PHE A N 1 ATOM 901 C CA . PHE A 1 119 ? 10.486 -22.100 -30.959 1.00 59.40 ? 119 PHE A CA 1 ATOM 902 C C . PHE A 1 119 ? 10.132 -20.630 -31.003 1.00 63.58 ? 119 PHE A C 1 ATOM 903 O O . PHE A 1 119 ? 10.305 -19.910 -30.010 1.00 62.19 ? 119 PHE A O 1 ATOM 904 C CB . PHE A 1 119 ? 9.778 -22.791 -29.792 1.00 60.73 ? 119 PHE A CB 1 ATOM 905 C CG . PHE A 1 119 ? 8.267 -22.778 -29.863 1.00 61.81 ? 119 PHE A CG 1 ATOM 906 C CD1 . PHE A 1 119 ? 7.541 -21.700 -29.378 1.00 63.91 ? 119 PHE A CD1 1 ATOM 907 C CD2 . PHE A 1 119 ? 7.566 -23.878 -30.346 1.00 64.69 ? 119 PHE A CD2 1 ATOM 908 C CE1 . PHE A 1 119 ? 6.145 -21.704 -29.411 1.00 64.87 ? 119 PHE A CE1 1 ATOM 909 C CE2 . PHE A 1 119 ? 6.167 -23.888 -30.364 1.00 67.20 ? 119 PHE A CE2 1 ATOM 910 C CZ . PHE A 1 119 ? 5.469 -22.799 -29.897 1.00 64.71 ? 119 PHE A CZ 1 ATOM 911 N N . THR A 1 120 ? 9.621 -20.198 -32.168 1.00 62.16 ? 120 THR A N 1 ATOM 912 C CA . THR A 1 120 ? 9.240 -18.821 -32.475 1.00 62.33 ? 120 THR A CA 1 ATOM 913 C C . THR A 1 120 ? 7.749 -18.782 -32.744 1.00 67.32 ? 120 THR A C 1 ATOM 914 O O . THR A 1 120 ? 7.287 -19.453 -33.676 1.00 67.25 ? 120 THR A O 1 ATOM 915 C CB . THR A 1 120 ? 10.028 -18.302 -33.707 1.00 67.90 ? 120 THR A CB 1 ATOM 916 O OG1 . THR A 1 120 ? 11.310 -18.932 -33.822 1.00 63.99 ? 120 THR A OG1 1 ATOM 917 C CG2 . THR A 1 120 ? 10.177 -16.804 -33.702 1.00 66.66 ? 120 THR A CG2 1 ATOM 918 N N . CYS A 1 121 ? 6.988 -18.019 -31.931 1.00 64.15 ? 121 CYS A N 1 ATOM 919 C CA . CYS A 1 121 ? 5.554 -17.918 -32.172 1.00 64.07 ? 121 CYS A CA 1 ATOM 920 C C . CYS A 1 121 ? 5.229 -16.877 -33.220 1.00 66.39 ? 121 CYS A C 1 ATOM 921 O O . CYS A 1 121 ? 5.738 -15.754 -33.167 1.00 66.55 ? 121 CYS A O 1 ATOM 922 C CB . CYS A 1 121 ? 4.781 -17.669 -30.899 1.00 65.19 ? 121 CYS A CB 1 ATOM 923 S SG . CYS A 1 121 ? 3.006 -17.943 -31.089 1.00 69.78 ? 121 CYS A SG 1 ATOM 924 N N . LYS A 1 122 ? 4.387 -17.258 -34.175 1.00 61.12 ? 122 LYS A N 1 ATOM 925 C CA . LYS A 1 122 ? 3.970 -16.436 -35.305 1.00 60.29 ? 122 LYS A CA 1 ATOM 926 C C . LYS A 1 122 ? 2.565 -15.787 -35.158 1.00 61.30 ? 122 LYS A C 1 ATOM 927 O O . LYS A 1 122 ? 2.335 -14.707 -35.683 1.00 60.33 ? 122 LYS A O 1 ATOM 928 C CB . LYS A 1 122 ? 4.042 -17.273 -36.575 1.00 63.58 ? 122 LYS A CB 1 ATOM 929 C CG . LYS A 1 122 ? 5.460 -17.488 -37.110 1.00 79.22 ? 122 LYS A CG 1 ATOM 930 C CD . LYS A 1 122 ? 5.490 -18.584 -38.187 1.00 94.23 ? 122 LYS A CD 1 ATOM 931 C CE . LYS A 1 122 ? 5.037 -18.173 -39.581 1.00 104.70 ? 122 LYS A CE 1 ATOM 932 N NZ . LYS A 1 122 ? 5.061 -19.329 -40.531 1.00 116.31 ? 122 LYS A NZ 1 ATOM 933 N N . LYS A 1 123 ? 1.639 -16.445 -34.487 1.00 56.71 ? 123 LYS A N 1 ATOM 934 C CA . LYS A 1 123 ? 0.276 -15.962 -34.245 1.00 56.22 ? 123 LYS A CA 1 ATOM 935 C C . LYS A 1 123 ? -0.122 -16.536 -32.888 1.00 59.16 ? 123 LYS A C 1 ATOM 936 O O . LYS A 1 123 ? 0.153 -17.702 -32.573 1.00 56.60 ? 123 LYS A O 1 ATOM 937 C CB . LYS A 1 123 ? -0.727 -16.424 -35.341 1.00 58.60 ? 123 LYS A CB 1 ATOM 938 C CG . LYS A 1 123 ? -0.910 -15.479 -36.508 1.00 67.55 ? 123 LYS A CG 1 ATOM 939 C CD . LYS A 1 123 ? -1.602 -16.165 -37.697 1.00 78.72 ? 123 LYS A CD 1 ATOM 940 C CE . LYS A 1 123 ? -1.317 -15.428 -39.003 1.00 91.09 ? 123 LYS A CE 1 ATOM 941 N NZ . LYS A 1 123 ? -2.058 -15.972 -40.179 1.00 93.31 ? 123 LYS A NZ 1 ATOM 942 N N . ASN A 1 124 ? -0.759 -15.704 -32.089 1.00 57.02 ? 124 ASN A N 1 ATOM 943 C CA . ASN A 1 124 ? -1.107 -16.038 -30.724 1.00 57.19 ? 124 ASN A CA 1 ATOM 944 C C . ASN A 1 124 ? -2.453 -15.424 -30.382 1.00 58.71 ? 124 ASN A C 1 ATOM 945 O O . ASN A 1 124 ? -2.969 -14.621 -31.166 1.00 56.66 ? 124 ASN A O 1 ATOM 946 C CB . ASN A 1 124 ? 0.024 -15.559 -29.760 1.00 61.26 ? 124 ASN A CB 1 ATOM 947 C CG . ASN A 1 124 ? 0.227 -14.053 -29.746 1.00 90.62 ? 124 ASN A CG 1 ATOM 948 O OD1 . ASN A 1 124 ? -0.556 -13.309 -29.132 1.00 86.86 ? 124 ASN A OD1 1 ATOM 949 N ND2 . ASN A 1 124 ? 1.258 -13.570 -30.459 1.00 78.60 ? 124 ASN A ND2 1 ATOM 950 N N . MET A 1 125 ? -3.024 -15.800 -29.228 1.00 54.61 ? 125 MET A N 1 ATOM 951 C CA . MET A 1 125 ? -4.338 -15.306 -28.864 1.00 54.31 ? 125 MET A CA 1 ATOM 952 C C . MET A 1 125 ? -4.504 -15.135 -27.358 1.00 62.20 ? 125 MET A C 1 ATOM 953 O O . MET A 1 125 ? -4.376 -16.088 -26.597 1.00 61.73 ? 125 MET A O 1 ATOM 954 C CB . MET A 1 125 ? -5.462 -16.158 -29.485 1.00 55.38 ? 125 MET A CB 1 ATOM 955 C CG . MET A 1 125 ? -5.158 -17.610 -29.531 1.00 58.73 ? 125 MET A CG 1 ATOM 956 S SD . MET A 1 125 ? -6.678 -18.577 -29.531 1.00 64.03 ? 125 MET A SD 1 ATOM 957 C CE . MET A 1 125 ? -6.201 -19.940 -28.596 1.00 60.85 ? 125 MET A CE 1 ATOM 958 N N . GLU A 1 126 ? -4.791 -13.895 -26.944 1.00 61.48 ? 126 GLU A N 1 ATOM 959 C CA . GLU A 1 126 ? -4.994 -13.489 -25.562 1.00 62.53 ? 126 GLU A CA 1 ATOM 960 C C . GLU A 1 126 ? -6.427 -13.750 -25.191 1.00 67.85 ? 126 GLU A C 1 ATOM 961 O O . GLU A 1 126 ? -7.312 -13.594 -26.021 1.00 67.24 ? 126 GLU A O 1 ATOM 962 C CB . GLU A 1 126 ? -4.720 -11.978 -25.391 1.00 64.61 ? 126 GLU A CB 1 ATOM 963 C CG . GLU A 1 126 ? -3.327 -11.491 -25.779 1.00 84.72 ? 126 GLU A CG 1 ATOM 964 C CD . GLU A 1 126 ? -3.092 -11.098 -27.233 1.00 132.11 ? 126 GLU A CD 1 ATOM 965 O OE1 . GLU A 1 126 ? -4.064 -10.739 -27.942 1.00 145.19 ? 126 GLU A OE1 1 ATOM 966 O OE2 . GLU A 1 126 ? -1.912 -11.115 -27.652 1.00 133.06 ? 126 GLU A OE2 1 ATOM 967 N N . GLY A 1 127 ? -6.644 -14.087 -23.937 1.00 67.07 ? 127 GLY A N 1 ATOM 968 C CA . GLY A 1 127 ? -7.966 -14.300 -23.372 1.00 68.81 ? 127 GLY A CA 1 ATOM 969 C C . GLY A 1 127 ? -8.057 -13.454 -22.120 1.00 78.09 ? 127 GLY A C 1 ATOM 970 O O . GLY A 1 127 ? -7.444 -13.798 -21.102 1.00 78.07 ? 127 GLY A O 1 ATOM 971 N N . LYS A 1 128 ? -8.764 -12.308 -22.197 1.00 77.51 ? 128 LYS A N 1 ATOM 972 C CA . LYS A 1 128 ? -8.855 -11.373 -21.075 1.00 78.13 ? 128 LYS A CA 1 ATOM 973 C C . LYS A 1 128 ? -9.974 -11.711 -20.079 1.00 87.67 ? 128 LYS A C 1 ATOM 974 O O . LYS A 1 128 ? -11.081 -12.038 -20.498 1.00 86.57 ? 128 LYS A O 1 ATOM 975 C CB . LYS A 1 128 ? -8.957 -9.938 -21.594 1.00 78.57 ? 128 LYS A CB 1 ATOM 976 C CG . LYS A 1 128 ? -7.604 -9.340 -21.975 1.00 80.79 ? 128 LYS A CG 1 ATOM 977 C CD . LYS A 1 128 ? -7.212 -9.613 -23.425 1.00 87.83 ? 128 LYS A CD 1 ATOM 978 C CE . LYS A 1 128 ? -5.956 -8.881 -23.838 1.00 96.04 ? 128 LYS A CE 1 ATOM 979 N NZ . LYS A 1 128 ? -6.249 -7.612 -24.559 1.00 103.35 ? 128 LYS A NZ 1 ATOM 980 N N . ILE A 1 129 ? -9.657 -11.674 -18.758 1.00 90.17 ? 129 ILE A N 1 ATOM 981 C CA . ILE A 1 129 ? -10.566 -11.947 -17.631 1.00 93.19 ? 129 ILE A CA 1 ATOM 982 C C . ILE A 1 129 ? -11.629 -10.861 -17.539 1.00 104.65 ? 129 ILE A C 1 ATOM 983 O O . ILE A 1 129 ? -11.315 -9.669 -17.375 1.00 104.44 ? 129 ILE A O 1 ATOM 984 C CB . ILE A 1 129 ? -9.850 -12.124 -16.240 1.00 96.33 ? 129 ILE A CB 1 ATOM 985 C CG1 . ILE A 1 129 ? -8.991 -13.401 -16.169 1.00 97.25 ? 129 ILE A CG1 1 ATOM 986 C CG2 . ILE A 1 129 ? -10.853 -12.097 -15.065 1.00 96.37 ? 129 ILE A CG2 1 ATOM 987 C CD1 . ILE A 1 129 ? -8.000 -13.508 -14.857 1.00 105.85 ? 129 ILE A CD1 1 ATOM 988 N N . VAL A 1 130 ? -12.892 -11.292 -17.585 1.00 106.21 ? 130 VAL A N 1 ATOM 989 C CA . VAL A 1 130 ? -13.994 -10.375 -17.422 1.00 108.19 ? 130 VAL A CA 1 ATOM 990 C C . VAL A 1 130 ? -14.714 -10.673 -16.106 1.00 116.05 ? 130 VAL A C 1 ATOM 991 O O . VAL A 1 130 ? -14.865 -11.837 -15.701 1.00 114.99 ? 130 VAL A O 1 ATOM 992 C CB . VAL A 1 130 ? -14.923 -10.282 -18.671 1.00 112.58 ? 130 VAL A CB 1 ATOM 993 C CG1 . VAL A 1 130 ? -16.163 -11.177 -18.566 1.00 112.33 ? 130 VAL A CG1 1 ATOM 994 C CG2 . VAL A 1 130 ? -15.313 -8.832 -18.953 1.00 112.50 ? 130 VAL A CG2 1 ATOM 995 N N . GLN A 1 131 ? -15.055 -9.588 -15.406 1.00 116.48 ? 131 GLN A N 1 ATOM 996 C CA . GLN A 1 131 ? -15.836 -9.567 -14.169 1.00 117.73 ? 131 GLN A CA 1 ATOM 997 C C . GLN A 1 131 ? -17.078 -8.721 -14.509 1.00 123.64 ? 131 GLN A C 1 ATOM 998 O O . GLN A 1 131 ? -16.922 -7.675 -15.155 1.00 122.82 ? 131 GLN A O 1 ATOM 999 C CB . GLN A 1 131 ? -15.058 -8.921 -12.993 1.00 119.11 ? 131 GLN A CB 1 ATOM 1000 C CG . GLN A 1 131 ? -13.772 -9.644 -12.571 1.00 132.05 ? 131 GLN A CG 1 ATOM 1001 C CD . GLN A 1 131 ? -12.500 -8.841 -12.800 1.00 149.35 ? 131 GLN A CD 1 ATOM 1002 O OE1 . GLN A 1 131 ? -12.508 -7.694 -13.278 1.00 146.61 ? 131 GLN A OE1 1 ATOM 1003 N NE2 . GLN A 1 131 ? -11.366 -9.439 -12.455 1.00 135.59 ? 131 GLN A NE2 1 ATOM 1004 N N . PRO A 1 132 ? -18.315 -9.133 -14.131 1.00 121.82 ? 132 PRO A N 1 ATOM 1005 C CA . PRO A 1 132 ? -19.489 -8.291 -14.457 1.00 122.15 ? 132 PRO A CA 1 ATOM 1006 C C . PRO A 1 132 ? -19.382 -6.867 -13.896 1.00 127.27 ? 132 PRO A C 1 ATOM 1007 O O . PRO A 1 132 ? -19.911 -5.944 -14.510 1.00 128.09 ? 132 PRO A O 1 ATOM 1008 C CB . PRO A 1 132 ? -20.670 -9.053 -13.843 1.00 123.61 ? 132 PRO A CB 1 ATOM 1009 C CG . PRO A 1 132 ? -20.179 -10.441 -13.634 1.00 127.91 ? 132 PRO A CG 1 ATOM 1010 C CD . PRO A 1 132 ? -18.707 -10.344 -13.379 1.00 123.35 ? 132 PRO A CD 1 ATOM 1011 N N . GLU A 1 133 ? -18.631 -6.690 -12.789 1.00 122.74 ? 133 GLU A N 1 ATOM 1012 C CA . GLU A 1 133 ? -18.389 -5.427 -12.094 1.00 122.02 ? 133 GLU A CA 1 ATOM 1013 C C . GLU A 1 133 ? -17.785 -4.344 -12.983 1.00 124.14 ? 133 GLU A C 1 ATOM 1014 O O . GLU A 1 133 ? -18.332 -3.246 -13.036 1.00 123.93 ? 133 GLU A O 1 ATOM 1015 C CB . GLU A 1 133 ? -17.511 -5.650 -10.845 1.00 123.59 ? 133 GLU A CB 1 ATOM 1016 C CG . GLU A 1 133 ? -18.191 -6.421 -9.718 1.00 136.03 ? 133 GLU A CG 1 ATOM 1017 C CD . GLU A 1 133 ? -18.301 -7.934 -9.850 1.00 156.78 ? 133 GLU A CD 1 ATOM 1018 O OE1 . GLU A 1 133 ? -17.632 -8.519 -10.734 1.00 149.66 ? 133 GLU A OE1 1 ATOM 1019 O OE2 . GLU A 1 133 ? -19.053 -8.537 -9.049 1.00 148.25 ? 133 GLU A OE2 1 ATOM 1020 N N . ASN A 1 134 ? -16.684 -4.644 -13.691 1.00 119.59 ? 134 ASN A N 1 ATOM 1021 C CA . ASN A 1 134 ? -16.011 -3.657 -14.537 1.00 119.36 ? 134 ASN A CA 1 ATOM 1022 C C . ASN A 1 134 ? -16.577 -3.560 -15.988 1.00 122.84 ? 134 ASN A C 1 ATOM 1023 O O . ASN A 1 134 ? -15.899 -3.002 -16.860 1.00 122.31 ? 134 ASN A O 1 ATOM 1024 C CB . ASN A 1 134 ? -14.480 -3.883 -14.530 1.00 121.42 ? 134 ASN A CB 1 ATOM 1025 C CG . ASN A 1 134 ? -13.982 -5.278 -14.890 1.00 141.31 ? 134 ASN A CG 1 ATOM 1026 O OD1 . ASN A 1 134 ? -14.693 -6.274 -14.788 1.00 132.35 ? 134 ASN A OD1 1 ATOM 1027 N ND2 . ASN A 1 134 ? -12.712 -5.390 -15.262 1.00 131.37 ? 134 ASN A ND2 1 ATOM 1028 N N . LEU A 1 135 ? -17.844 -4.032 -16.221 1.00 118.65 ? 135 LEU A N 1 ATOM 1029 C CA . LEU A 1 135 ? -18.543 -4.017 -17.525 1.00 117.67 ? 135 LEU A CA 1 ATOM 1030 C C . LEU A 1 135 ? -19.440 -2.756 -17.661 1.00 121.36 ? 135 LEU A C 1 ATOM 1031 O O . LEU A 1 135 ? -20.457 -2.651 -16.963 1.00 122.30 ? 135 LEU A O 1 ATOM 1032 C CB . LEU A 1 135 ? -19.430 -5.279 -17.645 1.00 117.13 ? 135 LEU A CB 1 ATOM 1033 C CG . LEU A 1 135 ? -19.507 -5.963 -18.996 1.00 121.23 ? 135 LEU A CG 1 ATOM 1034 C CD1 . LEU A 1 135 ? -20.139 -7.328 -18.847 1.00 121.09 ? 135 LEU A CD1 1 ATOM 1035 C CD2 . LEU A 1 135 ? -20.287 -5.137 -20.014 1.00 123.39 ? 135 LEU A CD2 1 ATOM 1036 N N . GLU A 1 136 ? -19.087 -1.828 -18.574 1.00 114.95 ? 136 GLU A N 1 ATOM 1037 C CA . GLU A 1 136 ? -19.831 -0.578 -18.778 1.00 113.31 ? 136 GLU A CA 1 ATOM 1038 C C . GLU A 1 136 ? -20.669 -0.550 -20.070 1.00 113.51 ? 136 GLU A C 1 ATOM 1039 O O . GLU A 1 136 ? -20.213 -1.002 -21.124 1.00 113.44 ? 136 GLU A O 1 ATOM 1040 C CB . GLU A 1 136 ? -18.860 0.619 -18.732 1.00 114.76 ? 136 GLU A CB 1 ATOM 1041 C CG . GLU A 1 136 ? -19.506 1.996 -18.746 1.00 126.70 ? 136 GLU A CG 1 ATOM 1042 C CD . GLU A 1 136 ? -18.532 3.133 -18.980 1.00 154.80 ? 136 GLU A CD 1 ATOM 1043 O OE1 . GLU A 1 136 ? -18.250 3.445 -20.161 1.00 155.08 ? 136 GLU A OE1 1 ATOM 1044 O OE2 . GLU A 1 136 ? -18.053 3.713 -17.981 1.00 149.37 ? 136 GLU A OE2 1 ATOM 1045 N N . TYR A 1 137 ? -21.883 0.030 -19.985 1.00 106.68 ? 137 TYR A N 1 ATOM 1046 C CA . TYR A 1 137 ? -22.787 0.191 -21.130 1.00 104.66 ? 137 TYR A CA 1 ATOM 1047 C C . TYR A 1 137 ? -22.970 1.674 -21.485 1.00 104.88 ? 137 TYR A C 1 ATOM 1048 O O . TYR A 1 137 ? -22.959 2.528 -20.593 1.00 104.85 ? 137 TYR A O 1 ATOM 1049 C CB . TYR A 1 137 ? -24.139 -0.486 -20.869 1.00 105.28 ? 137 TYR A CB 1 ATOM 1050 C CG . TYR A 1 137 ? -24.027 -1.928 -20.428 1.00 106.97 ? 137 TYR A CG 1 ATOM 1051 C CD1 . TYR A 1 137 ? -23.871 -2.952 -21.356 1.00 107.38 ? 137 TYR A CD1 1 ATOM 1052 C CD2 . TYR A 1 137 ? -24.075 -2.270 -19.080 1.00 109.17 ? 137 TYR A CD2 1 ATOM 1053 C CE1 . TYR A 1 137 ? -23.769 -4.283 -20.952 1.00 108.06 ? 137 TYR A CE1 1 ATOM 1054 C CE2 . TYR A 1 137 ? -23.982 -3.596 -18.665 1.00 109.37 ? 137 TYR A CE2 1 ATOM 1055 C CZ . TYR A 1 137 ? -23.829 -4.599 -19.606 1.00 115.17 ? 137 TYR A CZ 1 ATOM 1056 O OH . TYR A 1 137 ? -23.722 -5.907 -19.212 1.00 117.00 ? 137 TYR A OH 1 ATOM 1057 N N . THR A 1 138 ? -23.118 1.977 -22.783 1.00 97.58 ? 138 THR A N 1 ATOM 1058 C CA . THR A 1 138 ? -23.313 3.344 -23.274 1.00 95.62 ? 138 THR A CA 1 ATOM 1059 C C . THR A 1 138 ? -24.621 3.435 -24.058 1.00 95.02 ? 138 THR A C 1 ATOM 1060 O O . THR A 1 138 ? -24.710 2.927 -25.173 1.00 94.73 ? 138 THR A O 1 ATOM 1061 C CB . THR A 1 138 ? -22.079 3.813 -24.057 1.00 104.95 ? 138 THR A CB 1 ATOM 1062 O OG1 . THR A 1 138 ? -20.934 3.748 -23.204 1.00 105.42 ? 138 THR A OG1 1 ATOM 1063 C CG2 . THR A 1 138 ? -22.234 5.223 -24.643 1.00 103.20 ? 138 THR A CG2 1 ATOM 1064 N N . ILE A 1 139 ? -25.632 4.086 -23.451 1.00 88.34 ? 139 ILE A N 1 ATOM 1065 C CA . ILE A 1 139 ? -26.984 4.303 -23.988 1.00 85.63 ? 139 ILE A CA 1 ATOM 1066 C C . ILE A 1 139 ? -27.137 5.747 -24.432 1.00 86.64 ? 139 ILE A C 1 ATOM 1067 O O . ILE A 1 139 ? -26.666 6.647 -23.742 1.00 86.72 ? 139 ILE A O 1 ATOM 1068 C CB . ILE A 1 139 ? -28.051 3.901 -22.928 1.00 87.54 ? 139 ILE A CB 1 ATOM 1069 C CG1 . ILE A 1 139 ? -28.011 2.375 -22.661 1.00 87.08 ? 139 ILE A CG1 1 ATOM 1070 C CG2 . ILE A 1 139 ? -29.469 4.370 -23.328 1.00 87.40 ? 139 ILE A CG2 1 ATOM 1071 C CD1 . ILE A 1 139 ? -28.654 1.899 -21.417 1.00 90.31 ? 139 ILE A CD1 1 ATOM 1072 N N . VAL A 1 140 ? -27.776 5.962 -25.589 1.00 81.94 ? 140 VAL A N 1 ATOM 1073 C CA . VAL A 1 140 ? -28.071 7.297 -26.122 1.00 81.21 ? 140 VAL A CA 1 ATOM 1074 C C . VAL A 1 140 ? -29.607 7.534 -26.168 1.00 84.25 ? 140 VAL A C 1 ATOM 1075 O O . VAL A 1 140 ? -30.330 6.804 -26.856 1.00 84.42 ? 140 VAL A O 1 ATOM 1076 C CB . VAL A 1 140 ? -27.377 7.572 -27.464 1.00 84.01 ? 140 VAL A CB 1 ATOM 1077 C CG1 . VAL A 1 140 ? -27.878 8.875 -28.083 1.00 83.82 ? 140 VAL A CG1 1 ATOM 1078 C CG2 . VAL A 1 140 ? -25.872 7.622 -27.278 1.00 83.60 ? 140 VAL A CG2 1 ATOM 1079 N N . ILE A 1 141 ? -30.094 8.533 -25.411 1.00 78.03 ? 141 ILE A N 1 ATOM 1080 C CA . ILE A 1 141 ? -31.521 8.831 -25.396 1.00 76.85 ? 141 ILE A CA 1 ATOM 1081 C C . ILE A 1 141 ? -31.788 10.063 -26.220 1.00 79.07 ? 141 ILE A C 1 ATOM 1082 O O . ILE A 1 141 ? -31.305 11.134 -25.885 1.00 79.81 ? 141 ILE A O 1 ATOM 1083 C CB . ILE A 1 141 ? -32.112 8.960 -23.979 1.00 79.94 ? 141 ILE A CB 1 ATOM 1084 C CG1 . ILE A 1 141 ? -31.568 7.879 -23.035 1.00 80.64 ? 141 ILE A CG1 1 ATOM 1085 C CG2 . ILE A 1 141 ? -33.645 8.973 -24.026 1.00 79.40 ? 141 ILE A CG2 1 ATOM 1086 C CD1 . ILE A 1 141 ? -30.730 8.399 -21.997 1.00 91.04 ? 141 ILE A CD1 1 ATOM 1087 N N . THR A 1 142 ? -32.555 9.919 -27.291 1.00 73.74 ? 142 THR A N 1 ATOM 1088 C CA . THR A 1 142 ? -32.861 11.031 -28.174 1.00 72.41 ? 142 THR A CA 1 ATOM 1089 C C . THR A 1 142 ? -34.354 11.335 -28.181 1.00 76.56 ? 142 THR A C 1 ATOM 1090 O O . THR A 1 142 ? -35.128 10.550 -28.733 1.00 78.06 ? 142 THR A O 1 ATOM 1091 C CB . THR A 1 142 ? -32.313 10.773 -29.579 1.00 67.34 ? 142 THR A CB 1 ATOM 1092 O OG1 . THR A 1 142 ? -30.946 10.398 -29.477 1.00 66.82 ? 142 THR A OG1 1 ATOM 1093 C CG2 . THR A 1 142 ? -32.471 11.969 -30.493 1.00 59.62 ? 142 THR A CG2 1 ATOM 1094 N N . PRO A 1 143 ? -34.788 12.481 -27.626 1.00 70.69 ? 143 PRO A N 1 ATOM 1095 C CA . PRO A 1 143 ? -36.207 12.826 -27.707 1.00 69.22 ? 143 PRO A CA 1 ATOM 1096 C C . PRO A 1 143 ? -36.646 13.199 -29.124 1.00 69.87 ? 143 PRO A C 1 ATOM 1097 O O . PRO A 1 143 ? -35.822 13.605 -29.955 1.00 68.80 ? 143 PRO A O 1 ATOM 1098 C CB . PRO A 1 143 ? -36.342 14.001 -26.743 1.00 71.17 ? 143 PRO A CB 1 ATOM 1099 C CG . PRO A 1 143 ? -35.035 14.622 -26.728 1.00 76.81 ? 143 PRO A CG 1 ATOM 1100 C CD . PRO A 1 143 ? -34.024 13.531 -26.932 1.00 72.91 ? 143 PRO A CD 1 ATOM 1101 N N . HIS A 1 144 ? -37.951 12.989 -29.399 1.00 65.02 ? 144 HIS A N 1 ATOM 1102 C CA . HIS A 1 144 ? -38.619 13.304 -30.646 1.00 64.42 ? 144 HIS A CA 1 ATOM 1103 C C . HIS A 1 144 ? -39.050 14.775 -30.550 1.00 69.99 ? 144 HIS A C 1 ATOM 1104 O O . HIS A 1 144 ? -40.210 15.081 -30.241 1.00 67.93 ? 144 HIS A O 1 ATOM 1105 C CB . HIS A 1 144 ? -39.824 12.375 -30.846 1.00 64.88 ? 144 HIS A CB 1 ATOM 1106 C CG . HIS A 1 144 ? -39.540 11.160 -31.677 1.00 68.39 ? 144 HIS A CG 1 ATOM 1107 N ND1 . HIS A 1 144 ? -39.972 11.064 -32.991 1.00 70.27 ? 144 HIS A ND1 1 ATOM 1108 C CD2 . HIS A 1 144 ? -38.927 10.004 -31.341 1.00 70.16 ? 144 HIS A CD2 1 ATOM 1109 C CE1 . HIS A 1 144 ? -39.595 9.866 -33.414 1.00 69.41 ? 144 HIS A CE1 1 ATOM 1110 N NE2 . HIS A 1 144 ? -38.963 9.190 -32.459 1.00 69.74 ? 144 HIS A NE2 1 ATOM 1111 N N . SER A 1 145 ? -38.060 15.680 -30.747 1.00 70.12 ? 145 SER A N 1 ATOM 1112 C CA . SER A 1 145 ? -38.169 17.156 -30.708 1.00 71.63 ? 145 SER A CA 1 ATOM 1113 C C . SER A 1 145 ? -38.183 17.827 -32.071 1.00 80.61 ? 145 SER A C 1 ATOM 1114 O O . SER A 1 145 ? -37.987 19.053 -32.170 1.00 80.58 ? 145 SER A O 1 ATOM 1115 C CB . SER A 1 145 ? -37.028 17.761 -29.899 1.00 73.94 ? 145 SER A CB 1 ATOM 1116 O OG . SER A 1 145 ? -35.759 17.526 -30.487 1.00 80.61 ? 145 SER A OG 1 ATOM 1117 N N . GLY A 1 146 ? -38.459 17.061 -33.101 1.00 79.48 ? 146 GLY A N 1 ATOM 1118 C CA . GLY A 1 146 ? -38.510 17.566 -34.459 1.00 80.15 ? 146 GLY A CA 1 ATOM 1119 C C . GLY A 1 146 ? -37.253 18.225 -34.980 1.00 86.17 ? 146 GLY A C 1 ATOM 1120 O O . GLY A 1 146 ? -37.225 18.591 -36.150 1.00 85.54 ? 146 GLY A O 1 ATOM 1121 N N . GLU A 1 147 ? -36.204 18.363 -34.138 1.00 85.64 ? 147 GLU A N 1 ATOM 1122 C CA . GLU A 1 147 ? -34.936 18.995 -34.487 1.00 87.29 ? 147 GLU A CA 1 ATOM 1123 C C . GLU A 1 147 ? -34.497 18.617 -35.882 1.00 95.00 ? 147 GLU A C 1 ATOM 1124 O O . GLU A 1 147 ? -34.270 17.445 -36.184 1.00 94.42 ? 147 GLU A O 1 ATOM 1125 C CB . GLU A 1 147 ? -33.829 18.709 -33.455 1.00 88.87 ? 147 GLU A CB 1 ATOM 1126 C CG . GLU A 1 147 ? -32.735 19.776 -33.391 1.00 100.03 ? 147 GLU A CG 1 ATOM 1127 C CD . GLU A 1 147 ? -32.017 20.111 -34.688 1.00 120.92 ? 147 GLU A CD 1 ATOM 1128 O OE1 . GLU A 1 147 ? -31.183 19.299 -35.145 1.00 116.43 ? 147 GLU A OE1 1 ATOM 1129 O OE2 . GLU A 1 147 ? -32.372 21.142 -35.303 1.00 115.72 ? 147 GLU A OE2 1 ATOM 1130 N N . GLU A 1 148 ? -34.441 19.643 -36.738 1.00 95.11 ? 148 GLU A N 1 ATOM 1131 C CA . GLU A 1 148 ? -34.085 19.651 -38.152 1.00 96.90 ? 148 GLU A CA 1 ATOM 1132 C C . GLU A 1 148 ? -33.148 18.520 -38.594 1.00 104.30 ? 148 GLU A C 1 ATOM 1133 O O . GLU A 1 148 ? -33.431 17.880 -39.609 1.00 104.48 ? 148 GLU A O 1 ATOM 1134 C CB . GLU A 1 148 ? -33.501 21.028 -38.505 1.00 98.67 ? 148 GLU A CB 1 ATOM 1135 C CG . GLU A 1 148 ? -33.004 21.189 -39.931 1.00 110.98 ? 148 GLU A CG 1 ATOM 1136 C CD . GLU A 1 148 ? -32.246 22.478 -40.191 1.00 129.47 ? 148 GLU A CD 1 ATOM 1137 O OE1 . GLU A 1 148 ? -31.667 23.047 -39.237 1.00 105.60 ? 148 GLU A OE1 1 ATOM 1138 O OE2 . GLU A 1 148 ? -32.264 22.939 -41.354 1.00 130.13 ? 148 GLU A OE2 1 ATOM 1139 N N . HIS A 1 149 ? -32.077 18.245 -37.827 1.00 102.81 ? 149 HIS A N 1 ATOM 1140 C CA . HIS A 1 149 ? -31.092 17.228 -38.196 1.00 103.32 ? 149 HIS A CA 1 ATOM 1141 C C . HIS A 1 149 ? -31.316 15.848 -37.580 1.00 104.63 ? 149 HIS A C 1 ATOM 1142 O O . HIS A 1 149 ? -31.030 14.857 -38.252 1.00 103.70 ? 149 HIS A O 1 ATOM 1143 C CB . HIS A 1 149 ? -29.671 17.725 -37.893 1.00 104.98 ? 149 HIS A CB 1 ATOM 1144 C CG . HIS A 1 149 ? -29.342 19.006 -38.580 1.00 109.08 ? 149 HIS A CG 1 ATOM 1145 N ND1 . HIS A 1 149 ? -29.474 20.225 -37.934 1.00 111.23 ? 149 HIS A ND1 1 ATOM 1146 C CD2 . HIS A 1 149 ? -28.959 19.221 -39.862 1.00 111.68 ? 149 HIS A CD2 1 ATOM 1147 C CE1 . HIS A 1 149 ? -29.143 21.139 -38.834 1.00 111.31 ? 149 HIS A CE1 1 ATOM 1148 N NE2 . HIS A 1 149 ? -28.817 20.581 -40.009 1.00 111.73 ? 149 HIS A NE2 1 ATOM 1149 N N . ALA A 1 150 ? -31.830 15.787 -36.331 1.00 99.86 ? 150 ALA A N 1 ATOM 1150 C CA . ALA A 1 150 ? -32.076 14.587 -35.510 1.00 99.38 ? 150 ALA A CA 1 ATOM 1151 C C . ALA A 1 150 ? -32.418 13.256 -36.260 1.00 103.88 ? 150 ALA A C 1 ATOM 1152 O O . ALA A 1 150 ? -31.942 12.199 -35.829 1.00 103.14 ? 150 ALA A O 1 ATOM 1153 C CB . ALA A 1 150 ? -33.144 14.878 -34.476 1.00 99.84 ? 150 ALA A CB 1 ATOM 1154 N N . VAL A 1 151 ? -33.198 13.307 -37.370 1.00 101.38 ? 151 VAL A N 1 ATOM 1155 C CA . VAL A 1 151 ? -33.605 12.125 -38.162 1.00 101.47 ? 151 VAL A CA 1 ATOM 1156 C C . VAL A 1 151 ? -32.396 11.280 -38.589 1.00 108.09 ? 151 VAL A C 1 ATOM 1157 O O . VAL A 1 151 ? -31.561 11.733 -39.378 1.00 107.65 ? 151 VAL A O 1 ATOM 1158 C CB . VAL A 1 151 ? -34.540 12.474 -39.361 1.00 104.33 ? 151 VAL A CB 1 ATOM 1159 C CG1 . VAL A 1 151 ? -34.841 11.243 -40.221 1.00 103.61 ? 151 VAL A CG1 1 ATOM 1160 C CG2 . VAL A 1 151 ? -35.835 13.109 -38.876 1.00 103.93 ? 151 VAL A CG2 1 ATOM 1161 N N . GLY A 1 152 ? -32.321 10.075 -38.021 1.00 107.01 ? 152 GLY A N 1 ATOM 1162 C CA . GLY A 1 152 ? -31.256 9.101 -38.247 1.00 108.06 ? 152 GLY A CA 1 ATOM 1163 C C . GLY A 1 152 ? -29.851 9.639 -38.038 1.00 115.13 ? 152 GLY A C 1 ATOM 1164 O O . GLY A 1 152 ? -28.915 9.137 -38.667 1.00 114.96 ? 152 GLY A O 1 ATOM 1165 N N . ASN A 1 153 ? -29.700 10.692 -37.167 1.00 113.62 ? 153 ASN A N 1 ATOM 1166 C CA . ASN A 1 153 ? -28.412 11.329 -36.883 1.00 114.58 ? 153 ASN A CA 1 ATOM 1167 C C . ASN A 1 153 ? -27.528 10.417 -36.056 1.00 121.62 ? 153 ASN A C 1 ATOM 1168 O O . ASN A 1 153 ? -27.662 10.335 -34.828 1.00 120.78 ? 153 ASN A O 1 ATOM 1169 C CB . ASN A 1 153 ? -28.538 12.735 -36.275 1.00 115.60 ? 153 ASN A CB 1 ATOM 1170 C CG . ASN A 1 153 ? -27.264 13.536 -36.466 1.00 140.70 ? 153 ASN A CG 1 ATOM 1171 O OD1 . ASN A 1 153 ? -26.272 13.318 -35.766 1.00 134.58 ? 153 ASN A OD1 1 ATOM 1172 N ND2 . ASN A 1 153 ? -27.289 14.467 -37.431 1.00 135.50 ? 153 ASN A ND2 1 ATOM 1173 N N . ASP A 1 154 ? -26.632 9.710 -36.770 1.00 120.84 ? 154 ASP A N 1 ATOM 1174 C CA . ASP A 1 154 ? -25.692 8.701 -36.263 1.00 121.74 ? 154 ASP A CA 1 ATOM 1175 C C . ASP A 1 154 ? -24.651 9.260 -35.310 1.00 126.10 ? 154 ASP A C 1 ATOM 1176 O O . ASP A 1 154 ? -24.261 8.566 -34.372 1.00 124.80 ? 154 ASP A O 1 ATOM 1177 C CB . ASP A 1 154 ? -25.005 7.957 -37.430 1.00 124.36 ? 154 ASP A CB 1 ATOM 1178 C CG . ASP A 1 154 ? -24.588 8.818 -38.623 1.00 142.17 ? 154 ASP A CG 1 ATOM 1179 O OD1 . ASP A 1 154 ? -24.461 10.054 -38.455 1.00 143.94 ? 154 ASP A OD1 1 ATOM 1180 O OD2 . ASP A 1 154 ? -24.369 8.251 -39.719 1.00 150.23 ? 154 ASP A OD2 1 ATOM 1181 N N . THR A 1 155 ? -24.198 10.510 -35.577 1.00 123.87 ? 155 THR A N 1 ATOM 1182 C CA . THR A 1 155 ? -23.201 11.296 -34.836 1.00 123.94 ? 155 THR A CA 1 ATOM 1183 C C . THR A 1 155 ? -23.440 11.233 -33.317 1.00 127.63 ? 155 THR A C 1 ATOM 1184 O O . THR A 1 155 ? -22.537 10.843 -32.562 1.00 127.37 ? 155 THR A O 1 ATOM 1185 C CB . THR A 1 155 ? -23.186 12.729 -35.394 1.00 133.66 ? 155 THR A CB 1 ATOM 1186 O OG1 . THR A 1 155 ? -22.905 12.679 -36.797 1.00 129.78 ? 155 THR A OG1 1 ATOM 1187 C CG2 . THR A 1 155 ? -22.195 13.638 -34.685 1.00 134.05 ? 155 THR A CG2 1 ATOM 1188 N N . GLY A 1 156 ? -24.672 11.553 -32.915 1.00 123.79 ? 156 GLY A N 1 ATOM 1189 C CA . GLY A 1 156 ? -25.112 11.479 -31.529 1.00 123.41 ? 156 GLY A CA 1 ATOM 1190 C C . GLY A 1 156 ? -25.377 12.787 -30.821 1.00 125.54 ? 156 GLY A C 1 ATOM 1191 O O . GLY A 1 156 ? -26.149 12.814 -29.857 1.00 124.78 ? 156 GLY A O 1 ATOM 1192 N N . LYS A 1 157 ? -24.741 13.874 -31.290 1.00 121.47 ? 157 LYS A N 1 ATOM 1193 C CA . LYS A 1 157 ? -24.813 15.223 -30.717 1.00 121.03 ? 157 LYS A CA 1 ATOM 1194 C C . LYS A 1 157 ? -26.201 15.612 -30.144 1.00 124.31 ? 157 LYS A C 1 ATOM 1195 O O . LYS A 1 157 ? -26.272 16.228 -29.074 1.00 124.42 ? 157 LYS A O 1 ATOM 1196 C CB . LYS A 1 157 ? -24.331 16.256 -31.746 1.00 122.97 ? 157 LYS A CB 1 ATOM 1197 C CG . LYS A 1 157 ? -22.833 16.221 -31.997 1.00 131.44 ? 157 LYS A CG 1 ATOM 1198 C CD . LYS A 1 157 ? -22.448 16.973 -33.264 1.00 140.25 ? 157 LYS A CD 1 ATOM 1199 C CE . LYS A 1 157 ? -20.949 16.985 -33.487 1.00 142.76 ? 157 LYS A CE 1 ATOM 1200 N NZ . LYS A 1 157 ? -20.589 17.352 -34.885 1.00 140.43 ? 157 LYS A NZ 1 ATOM 1201 N N . HIS A 1 158 ? -27.287 15.212 -30.840 1.00 119.24 ? 158 HIS A N 1 ATOM 1202 C CA . HIS A 1 158 ? -28.690 15.473 -30.486 1.00 118.26 ? 158 HIS A CA 1 ATOM 1203 C C . HIS A 1 158 ? -29.187 14.811 -29.183 1.00 119.84 ? 158 HIS A C 1 ATOM 1204 O O . HIS A 1 158 ? -30.096 15.333 -28.529 1.00 119.26 ? 158 HIS A O 1 ATOM 1205 C CB . HIS A 1 158 ? -29.601 15.009 -31.628 1.00 119.00 ? 158 HIS A CB 1 ATOM 1206 C CG . HIS A 1 158 ? -29.424 15.754 -32.908 1.00 122.26 ? 158 HIS A CG 1 ATOM 1207 N ND1 . HIS A 1 158 ? -28.578 15.289 -33.897 1.00 123.97 ? 158 HIS A ND1 1 ATOM 1208 C CD2 . HIS A 1 158 ? -30.034 16.879 -33.344 1.00 123.71 ? 158 HIS A CD2 1 ATOM 1209 C CE1 . HIS A 1 158 ? -28.687 16.152 -34.892 1.00 123.17 ? 158 HIS A CE1 1 ATOM 1210 N NE2 . HIS A 1 158 ? -29.553 17.122 -34.605 1.00 123.46 ? 158 HIS A NE2 1 ATOM 1211 N N . GLY A 1 159 ? -28.646 13.645 -28.865 1.00 114.68 ? 159 GLY A N 1 ATOM 1212 C CA . GLY A 1 159 ? -29.079 12.890 -27.700 1.00 113.59 ? 159 GLY A CA 1 ATOM 1213 C C . GLY A 1 159 ? -28.155 12.957 -26.507 1.00 115.61 ? 159 GLY A C 1 ATOM 1214 O O . GLY A 1 159 ? -26.961 13.212 -26.649 1.00 114.96 ? 159 GLY A O 1 ATOM 1215 N N . LYS A 1 160 ? -28.707 12.708 -25.321 1.00 111.13 ? 160 LYS A N 1 ATOM 1216 C CA . LYS A 1 160 ? -27.959 12.677 -24.069 1.00 110.15 ? 160 LYS A CA 1 ATOM 1217 C C . LYS A 1 160 ? -27.366 11.276 -23.842 1.00 111.85 ? 160 LYS A C 1 ATOM 1218 O O . LYS A 1 160 ? -28.114 10.298 -23.675 1.00 109.94 ? 160 LYS A O 1 ATOM 1219 C CB . LYS A 1 160 ? -28.853 13.104 -22.872 1.00 112.23 ? 160 LYS A CB 1 ATOM 1220 C CG . LYS A 1 160 ? -28.130 13.168 -21.509 1.00 119.43 ? 160 LYS A CG 1 ATOM 1221 C CD . LYS A 1 160 ? -27.471 14.543 -21.256 1.00 122.36 ? 160 LYS A CD 1 ATOM 1222 C CE . LYS A 1 160 ? -26.521 14.569 -20.079 1.00 114.81 ? 160 LYS A CE 1 ATOM 1223 N NZ . LYS A 1 160 ? -25.101 14.382 -20.489 1.00 107.07 ? 160 LYS A NZ 1 ATOM 1224 N N . GLU A 1 161 ? -26.013 11.199 -23.845 1.00 107.62 ? 161 GLU A N 1 ATOM 1225 C CA . GLU A 1 161 ? -25.250 9.981 -23.585 1.00 107.01 ? 161 GLU A CA 1 ATOM 1226 C C . GLU A 1 161 ? -25.378 9.639 -22.105 1.00 110.18 ? 161 GLU A C 1 ATOM 1227 O O . GLU A 1 161 ? -25.389 10.548 -21.262 1.00 109.25 ? 161 GLU A O 1 ATOM 1228 C CB . GLU A 1 161 ? -23.769 10.188 -23.930 1.00 108.36 ? 161 GLU A CB 1 ATOM 1229 C CG . GLU A 1 161 ? -23.390 9.697 -25.312 1.00 120.81 ? 161 GLU A CG 1 ATOM 1230 C CD . GLU A 1 161 ? -21.934 9.312 -25.524 1.00 145.91 ? 161 GLU A CD 1 ATOM 1231 O OE1 . GLU A 1 161 ? -21.311 8.759 -24.587 1.00 150.90 ? 161 GLU A OE1 1 ATOM 1232 O OE2 . GLU A 1 161 ? -21.439 9.495 -26.661 1.00 135.26 ? 161 GLU A OE2 1 ATOM 1233 N N . ILE A 1 162 ? -25.498 8.334 -21.784 1.00 106.33 ? 162 ILE A N 1 ATOM 1234 C CA . ILE A 1 162 ? -25.604 7.874 -20.398 1.00 106.18 ? 162 ILE A CA 1 ATOM 1235 C C . ILE A 1 162 ? -24.851 6.557 -20.212 1.00 111.94 ? 162 ILE A C 1 ATOM 1236 O O . ILE A 1 162 ? -24.898 5.693 -21.100 1.00 111.56 ? 162 ILE A O 1 ATOM 1237 C CB . ILE A 1 162 ? -27.050 7.826 -19.830 1.00 108.89 ? 162 ILE A CB 1 ATOM 1238 C CG1 . ILE A 1 162 ? -27.781 6.529 -20.276 1.00 108.51 ? 162 ILE A CG1 1 ATOM 1239 C CG2 . ILE A 1 162 ? -27.855 9.099 -20.096 1.00 110.28 ? 162 ILE A CG2 1 ATOM 1240 C CD1 . ILE A 1 162 ? -28.719 6.020 -19.354 1.00 108.78 ? 162 ILE A CD1 1 ATOM 1241 N N . LYS A 1 163 ? -24.191 6.404 -19.041 1.00 109.67 ? 163 LYS A N 1 ATOM 1242 C CA . LYS A 1 163 ? -23.383 5.234 -18.703 1.00 109.67 ? 163 LYS A CA 1 ATOM 1243 C C . LYS A 1 163 ? -24.028 4.401 -17.628 1.00 113.80 ? 163 LYS A C 1 ATOM 1244 O O . LYS A 1 163 ? -24.357 4.906 -16.553 1.00 114.03 ? 163 LYS A O 1 ATOM 1245 C CB . LYS A 1 163 ? -21.951 5.630 -18.294 1.00 111.93 ? 163 LYS A CB 1 ATOM 1246 C CG . LYS A 1 163 ? -21.297 6.705 -19.160 1.00 123.92 ? 163 LYS A CG 1 ATOM 1247 C CD . LYS A 1 163 ? -20.582 6.130 -20.373 1.00 135.89 ? 163 LYS A CD 1 ATOM 1248 C CE . LYS A 1 163 ? -20.026 7.220 -21.260 1.00 150.19 ? 163 LYS A CE 1 ATOM 1249 N NZ . LYS A 1 163 ? -19.266 6.666 -22.414 1.00 160.84 ? 163 LYS A NZ 1 ATOM 1250 N N . ILE A 1 164 ? -24.260 3.142 -17.939 1.00 110.56 ? 164 ILE A N 1 ATOM 1251 C CA . ILE A 1 164 ? -24.847 2.265 -16.957 1.00 111.39 ? 164 ILE A CA 1 ATOM 1252 C C . ILE A 1 164 ? -23.713 1.322 -16.482 1.00 120.00 ? 164 ILE A C 1 ATOM 1253 O O . ILE A 1 164 ? -23.047 0.654 -17.288 1.00 120.02 ? 164 ILE A O 1 ATOM 1254 C CB . ILE A 1 164 ? -26.201 1.641 -17.435 1.00 113.84 ? 164 ILE A CB 1 ATOM 1255 C CG1 . ILE A 1 164 ? -27.362 2.157 -16.569 1.00 113.72 ? 164 ILE A CG1 1 ATOM 1256 C CG2 . ILE A 1 164 ? -26.228 0.118 -17.541 1.00 114.14 ? 164 ILE A CG2 1 ATOM 1257 C CD1 . ILE A 1 164 ? -28.359 2.969 -17.283 1.00 114.48 ? 164 ILE A CD1 1 ATOM 1258 N N . THR A 1 165 ? -23.401 1.437 -15.175 1.00 118.65 ? 165 THR A N 1 ATOM 1259 C CA . THR A 1 165 ? -22.348 0.722 -14.450 1.00 118.96 ? 165 THR A CA 1 ATOM 1260 C C . THR A 1 165 ? -23.027 -0.203 -13.420 1.00 125.14 ? 165 THR A C 1 ATOM 1261 O O . THR A 1 165 ? -23.967 0.253 -12.761 1.00 125.51 ? 165 THR A O 1 ATOM 1262 C CB . THR A 1 165 ? -21.447 1.767 -13.750 1.00 123.10 ? 165 THR A CB 1 ATOM 1263 O OG1 . THR A 1 165 ? -20.916 2.657 -14.728 1.00 119.74 ? 165 THR A OG1 1 ATOM 1264 C CG2 . THR A 1 165 ? -20.308 1.151 -12.945 1.00 121.97 ? 165 THR A CG2 1 ATOM 1265 N N . PRO A 1 166 ? -22.560 -1.466 -13.213 1.00 121.68 ? 166 PRO A N 1 ATOM 1266 C CA . PRO A 1 166 ? -23.198 -2.339 -12.200 1.00 121.25 ? 166 PRO A CA 1 ATOM 1267 C C . PRO A 1 166 ? -23.042 -1.828 -10.767 1.00 123.93 ? 166 PRO A C 1 ATOM 1268 O O . PRO A 1 166 ? -23.712 -2.322 -9.852 1.00 122.36 ? 166 PRO A O 1 ATOM 1269 C CB . PRO A 1 166 ? -22.512 -3.687 -12.416 1.00 123.12 ? 166 PRO A CB 1 ATOM 1270 C CG . PRO A 1 166 ? -21.927 -3.589 -13.804 1.00 127.69 ? 166 PRO A CG 1 ATOM 1271 C CD . PRO A 1 166 ? -21.475 -2.182 -13.904 1.00 123.13 ? 166 PRO A CD 1 ATOM 1272 N N . GLN A 1 167 ? -22.181 -0.797 -10.596 1.00 121.12 ? 167 GLN A N 1 ATOM 1273 C CA . GLN A 1 167 ? -21.929 -0.084 -9.343 1.00 121.00 ? 167 GLN A CA 1 ATOM 1274 C C . GLN A 1 167 ? -22.945 1.083 -9.196 1.00 126.15 ? 167 GLN A C 1 ATOM 1275 O O . GLN A 1 167 ? -23.334 1.404 -8.062 1.00 126.18 ? 167 GLN A O 1 ATOM 1276 C CB . GLN A 1 167 ? -20.480 0.433 -9.278 1.00 121.81 ? 167 GLN A CB 1 ATOM 1277 C CG . GLN A 1 167 ? -19.402 -0.586 -9.692 1.00 132.15 ? 167 GLN A CG 1 ATOM 1278 C CD . GLN A 1 167 ? -19.231 -1.814 -8.805 1.00 146.67 ? 167 GLN A CD 1 ATOM 1279 O OE1 . GLN A 1 167 ? -18.871 -2.899 -9.276 1.00 141.24 ? 167 GLN A OE1 1 ATOM 1280 N NE2 . GLN A 1 167 ? -19.406 -1.676 -7.500 1.00 135.60 ? 167 GLN A NE2 1 ATOM 1281 N N . SER A 1 168 ? -23.395 1.685 -10.352 1.00 122.02 ? 168 SER A N 1 ATOM 1282 C CA . SER A 1 168 ? -24.384 2.785 -10.432 1.00 121.03 ? 168 SER A CA 1 ATOM 1283 C C . SER A 1 168 ? -25.605 2.462 -11.359 1.00 122.82 ? 168 SER A C 1 ATOM 1284 O O . SER A 1 168 ? -26.016 3.318 -12.157 1.00 123.06 ? 168 SER A O 1 ATOM 1285 C CB . SER A 1 168 ? -23.705 4.094 -10.847 1.00 124.27 ? 168 SER A CB 1 ATOM 1286 O OG . SER A 1 168 ? -23.429 4.157 -12.238 1.00 132.68 ? 168 SER A OG 1 ATOM 1287 N N . SER A 1 169 ? -26.185 1.228 -11.228 1.00 116.26 ? 169 SER A N 1 ATOM 1288 C CA . SER A 1 169 ? -27.313 0.684 -12.020 1.00 114.06 ? 169 SER A CA 1 ATOM 1289 C C . SER A 1 169 ? -28.491 1.664 -12.275 1.00 115.23 ? 169 SER A C 1 ATOM 1290 O O . SER A 1 169 ? -29.088 1.613 -13.357 1.00 114.73 ? 169 SER A O 1 ATOM 1291 C CB . SER A 1 169 ? -27.833 -0.614 -11.409 1.00 114.87 ? 169 SER A CB 1 ATOM 1292 O OG . SER A 1 169 ? -27.186 -1.745 -11.969 1.00 116.42 ? 169 SER A OG 1 ATOM 1293 N N . THR A 1 170 ? -28.803 2.555 -11.298 1.00 109.23 ? 170 THR A N 1 ATOM 1294 C CA . THR A 1 170 ? -29.873 3.562 -11.393 1.00 107.30 ? 170 THR A CA 1 ATOM 1295 C C . THR A 1 170 ? -29.295 4.945 -11.756 1.00 108.95 ? 170 THR A C 1 ATOM 1296 O O . THR A 1 170 ? -28.578 5.553 -10.951 1.00 107.63 ? 170 THR A O 1 ATOM 1297 C CB . THR A 1 170 ? -30.742 3.547 -10.126 1.00 103.64 ? 170 THR A CB 1 ATOM 1298 O OG1 . THR A 1 170 ? -31.368 2.274 -10.038 1.00 94.07 ? 170 THR A OG1 1 ATOM 1299 C CG2 . THR A 1 170 ? -31.802 4.627 -10.121 1.00 101.49 ? 170 THR A CG2 1 ATOM 1300 N N . THR A 1 171 ? -29.625 5.427 -12.981 1.00 104.54 ? 171 THR A N 1 ATOM 1301 C CA . THR A 1 171 ? -29.170 6.720 -13.524 1.00 103.68 ? 171 THR A CA 1 ATOM 1302 C C . THR A 1 171 ? -30.344 7.595 -13.992 1.00 107.54 ? 171 THR A C 1 ATOM 1303 O O . THR A 1 171 ? -31.193 7.136 -14.754 1.00 106.97 ? 171 THR A O 1 ATOM 1304 C CB . THR A 1 171 ? -28.103 6.550 -14.605 1.00 107.11 ? 171 THR A CB 1 ATOM 1305 O OG1 . THR A 1 171 ? -27.236 5.454 -14.288 1.00 108.00 ? 171 THR A OG1 1 ATOM 1306 C CG2 . THR A 1 171 ? -27.261 7.803 -14.775 1.00 103.63 ? 171 THR A CG2 1 ATOM 1307 N N . GLU A 1 172 ? -30.350 8.872 -13.532 1.00 104.35 ? 172 GLU A N 1 ATOM 1308 C CA . GLU A 1 172 ? -31.357 9.930 -13.726 1.00 103.78 ? 172 GLU A CA 1 ATOM 1309 C C . GLU A 1 172 ? -30.804 11.019 -14.665 1.00 105.26 ? 172 GLU A C 1 ATOM 1310 O O . GLU A 1 172 ? -30.197 11.986 -14.197 1.00 105.15 ? 172 GLU A O 1 ATOM 1311 C CB . GLU A 1 172 ? -31.729 10.531 -12.328 1.00 105.51 ? 172 GLU A CB 1 ATOM 1312 C CG . GLU A 1 172 ? -32.898 11.522 -12.286 1.00 120.03 ? 172 GLU A CG 1 ATOM 1313 C CD . GLU A 1 172 ? -33.135 12.281 -10.985 1.00 138.15 ? 172 GLU A CD 1 ATOM 1314 O OE1 . GLU A 1 172 ? -33.324 11.629 -9.931 1.00 119.10 ? 172 GLU A OE1 1 ATOM 1315 O OE2 . GLU A 1 172 ? -33.199 13.533 -11.035 1.00 131.79 ? 172 GLU A OE2 1 ATOM 1316 N N . ALA A 1 173 ? -31.000 10.873 -15.980 1.00 99.67 ? 173 ALA A N 1 ATOM 1317 C CA . ALA A 1 173 ? -30.481 11.896 -16.884 1.00 98.69 ? 173 ALA A CA 1 ATOM 1318 C C . ALA A 1 173 ? -31.458 13.037 -17.109 1.00 99.90 ? 173 ALA A C 1 ATOM 1319 O O . ALA A 1 173 ? -32.644 12.805 -17.369 1.00 99.02 ? 173 ALA A O 1 ATOM 1320 C CB . ALA A 1 173 ? -30.080 11.282 -18.204 1.00 99.56 ? 173 ALA A CB 1 ATOM 1321 N N . GLU A 1 174 ? -30.959 14.271 -17.001 1.00 95.29 ? 174 GLU A N 1 ATOM 1322 C CA . GLU A 1 174 ? -31.786 15.452 -17.228 1.00 94.94 ? 174 GLU A CA 1 ATOM 1323 C C . GLU A 1 174 ? -31.794 15.832 -18.705 1.00 95.68 ? 174 GLU A C 1 ATOM 1324 O O . GLU A 1 174 ? -30.810 16.364 -19.248 1.00 95.07 ? 174 GLU A O 1 ATOM 1325 C CB . GLU A 1 174 ? -31.396 16.649 -16.333 1.00 96.76 ? 174 GLU A CB 1 ATOM 1326 C CG . GLU A 1 174 ? -32.537 17.636 -16.060 1.00 112.05 ? 174 GLU A CG 1 ATOM 1327 C CD . GLU A 1 174 ? -32.984 18.603 -17.150 1.00 137.20 ? 174 GLU A CD 1 ATOM 1328 O OE1 . GLU A 1 174 ? -32.114 19.269 -17.760 1.00 133.43 ? 174 GLU A OE1 1 ATOM 1329 O OE2 . GLU A 1 174 ? -34.215 18.756 -17.331 1.00 127.54 ? 174 GLU A OE2 1 ATOM 1330 N N . LEU A 1 175 ? -32.935 15.556 -19.344 1.00 88.97 ? 175 LEU A N 1 ATOM 1331 C CA . LEU A 1 175 ? -33.174 15.881 -20.738 1.00 86.83 ? 175 LEU A CA 1 ATOM 1332 C C . LEU A 1 175 ? -33.614 17.347 -20.835 1.00 89.15 ? 175 LEU A C 1 ATOM 1333 O O . LEU A 1 175 ? -34.628 17.751 -20.248 1.00 88.58 ? 175 LEU A O 1 ATOM 1334 C CB . LEU A 1 175 ? -34.212 14.925 -21.349 1.00 86.33 ? 175 LEU A CB 1 ATOM 1335 C CG . LEU A 1 175 ? -33.829 13.446 -21.423 1.00 90.16 ? 175 LEU A CG 1 ATOM 1336 C CD1 . LEU A 1 175 ? -35.048 12.586 -21.599 1.00 90.07 ? 175 LEU A CD1 1 ATOM 1337 C CD2 . LEU A 1 175 ? -32.855 13.176 -22.546 1.00 92.83 ? 175 LEU A CD2 1 ATOM 1338 N N . THR A 1 176 ? -32.794 18.144 -21.538 1.00 84.80 ? 176 THR A N 1 ATOM 1339 C CA . THR A 1 176 ? -32.956 19.582 -21.777 1.00 84.23 ? 176 THR A CA 1 ATOM 1340 C C . THR A 1 176 ? -34.331 19.928 -22.414 1.00 87.67 ? 176 THR A C 1 ATOM 1341 O O . THR A 1 176 ? -34.496 19.912 -23.646 1.00 87.03 ? 176 THR A O 1 ATOM 1342 C CB . THR A 1 176 ? -31.770 20.104 -22.635 1.00 87.50 ? 176 THR A CB 1 ATOM 1343 O OG1 . THR A 1 176 ? -30.567 19.383 -22.338 1.00 84.40 ? 176 THR A OG1 1 ATOM 1344 C CG2 . THR A 1 176 ? -31.574 21.612 -22.517 1.00 81.58 ? 176 THR A CG2 1 ATOM 1345 N N . GLY A 1 177 ? -35.289 20.240 -21.556 1.00 83.59 ? 177 GLY A N 1 ATOM 1346 C CA . GLY A 1 177 ? -36.628 20.631 -21.976 1.00 83.31 ? 177 GLY A CA 1 ATOM 1347 C C . GLY A 1 177 ? -37.734 19.629 -21.703 1.00 86.82 ? 177 GLY A C 1 ATOM 1348 O O . GLY A 1 177 ? -38.918 19.947 -21.887 1.00 86.05 ? 177 GLY A O 1 ATOM 1349 N N . TYR A 1 178 ? -37.364 18.418 -21.252 1.00 83.14 ? 178 TYR A N 1 ATOM 1350 C CA . TYR A 1 178 ? -38.347 17.364 -21.005 1.00 83.18 ? 178 TYR A CA 1 ATOM 1351 C C . TYR A 1 178 ? -38.351 16.842 -19.579 1.00 88.60 ? 178 TYR A C 1 ATOM 1352 O O . TYR A 1 178 ? -39.240 16.069 -19.218 1.00 87.84 ? 178 TYR A O 1 ATOM 1353 C CB . TYR A 1 178 ? -38.157 16.220 -22.016 1.00 83.86 ? 178 TYR A CB 1 ATOM 1354 C CG . TYR A 1 178 ? -38.248 16.686 -23.451 1.00 84.99 ? 178 TYR A CG 1 ATOM 1355 C CD1 . TYR A 1 178 ? -39.477 16.782 -24.098 1.00 86.70 ? 178 TYR A CD1 1 ATOM 1356 C CD2 . TYR A 1 178 ? -37.114 17.089 -24.145 1.00 85.42 ? 178 TYR A CD2 1 ATOM 1357 C CE1 . TYR A 1 178 ? -39.569 17.226 -25.410 1.00 86.07 ? 178 TYR A CE1 1 ATOM 1358 C CE2 . TYR A 1 178 ? -37.197 17.555 -25.450 1.00 86.05 ? 178 TYR A CE2 1 ATOM 1359 C CZ . TYR A 1 178 ? -38.428 17.624 -26.078 1.00 90.32 ? 178 TYR A CZ 1 ATOM 1360 O OH . TYR A 1 178 ? -38.524 18.085 -27.363 1.00 87.00 ? 178 TYR A OH 1 ATOM 1361 N N . GLY A 1 179 ? -37.374 17.279 -18.788 1.00 86.07 ? 179 GLY A N 1 ATOM 1362 C CA . GLY A 1 179 ? -37.221 16.851 -17.408 1.00 86.70 ? 179 GLY A CA 1 ATOM 1363 C C . GLY A 1 179 ? -36.269 15.686 -17.268 1.00 92.72 ? 179 GLY A C 1 ATOM 1364 O O . GLY A 1 179 ? -35.358 15.530 -18.079 1.00 92.13 ? 179 GLY A O 1 ATOM 1365 N N . THR A 1 180 ? -36.474 14.860 -16.245 1.00 91.40 ? 180 THR A N 1 ATOM 1366 C CA . THR A 1 180 ? -35.598 13.726 -15.993 1.00 92.37 ? 180 THR A CA 1 ATOM 1367 C C . THR A 1 180 ? -36.295 12.384 -16.299 1.00 96.80 ? 180 THR A C 1 ATOM 1368 O O . THR A 1 180 ? -37.530 12.261 -16.237 1.00 96.26 ? 180 THR A O 1 ATOM 1369 C CB . THR A 1 180 ? -34.973 13.789 -14.556 1.00 107.59 ? 180 THR A CB 1 ATOM 1370 O OG1 . THR A 1 180 ? -35.970 13.708 -13.535 1.00 113.81 ? 180 THR A OG1 1 ATOM 1371 C CG2 . THR A 1 180 ? -34.080 15.004 -14.323 1.00 104.28 ? 180 THR A CG2 1 ATOM 1372 N N . VAL A 1 181 ? -35.474 11.383 -16.635 1.00 93.69 ? 181 VAL A N 1 ATOM 1373 C CA . VAL A 1 181 ? -35.913 10.013 -16.886 1.00 94.11 ? 181 VAL A CA 1 ATOM 1374 C C . VAL A 1 181 ? -34.992 9.119 -16.063 1.00 97.98 ? 181 VAL A C 1 ATOM 1375 O O . VAL A 1 181 ? -33.765 9.167 -16.232 1.00 97.07 ? 181 VAL A O 1 ATOM 1376 C CB . VAL A 1 181 ? -35.978 9.624 -18.395 1.00 98.56 ? 181 VAL A CB 1 ATOM 1377 C CG1 . VAL A 1 181 ? -34.610 9.712 -19.071 1.00 98.26 ? 181 VAL A CG1 1 ATOM 1378 C CG2 . VAL A 1 181 ? -36.612 8.245 -18.602 1.00 98.35 ? 181 VAL A CG2 1 ATOM 1379 N N . THR A 1 182 ? -35.550 8.380 -15.108 1.00 95.24 ? 182 THR A N 1 ATOM 1380 C CA . THR A 1 182 ? -34.658 7.516 -14.364 1.00 95.62 ? 182 THR A CA 1 ATOM 1381 C C . THR A 1 182 ? -34.708 6.175 -15.059 1.00 99.67 ? 182 THR A C 1 ATOM 1382 O O . THR A 1 182 ? -35.771 5.669 -15.432 1.00 98.48 ? 182 THR A O 1 ATOM 1383 C CB . THR A 1 182 ? -34.846 7.561 -12.828 1.00 108.13 ? 182 THR A CB 1 ATOM 1384 O OG1 . THR A 1 182 ? -33.549 7.612 -12.220 1.00 106.94 ? 182 THR A OG1 1 ATOM 1385 C CG2 . THR A 1 182 ? -35.609 6.367 -12.260 1.00 108.14 ? 182 THR A CG2 1 ATOM 1386 N N . MET A 1 183 ? -33.523 5.661 -15.305 1.00 97.60 ? 183 MET A N 1 ATOM 1387 C CA . MET A 1 183 ? -33.285 4.416 -16.000 1.00 97.88 ? 183 MET A CA 1 ATOM 1388 C C . MET A 1 183 ? -32.700 3.377 -15.064 1.00 104.13 ? 183 MET A C 1 ATOM 1389 O O . MET A 1 183 ? -31.682 3.636 -14.409 1.00 104.11 ? 183 MET A O 1 ATOM 1390 C CB . MET A 1 183 ? -32.335 4.670 -17.159 1.00 99.90 ? 183 MET A CB 1 ATOM 1391 C CG . MET A 1 183 ? -32.639 3.787 -18.327 1.00 103.59 ? 183 MET A CG 1 ATOM 1392 S SD . MET A 1 183 ? -31.792 4.248 -19.804 1.00 107.76 ? 183 MET A SD 1 ATOM 1393 C CE . MET A 1 183 ? -32.505 5.839 -20.062 1.00 104.71 ? 183 MET A CE 1 ATOM 1394 N N . GLU A 1 184 ? -33.355 2.208 -15.000 1.00 102.03 ? 184 GLU A N 1 ATOM 1395 C CA . GLU A 1 184 ? -32.935 1.109 -14.153 1.00 103.30 ? 184 GLU A CA 1 ATOM 1396 C C . GLU A 1 184 ? -32.673 -0.124 -15.006 1.00 110.45 ? 184 GLU A C 1 ATOM 1397 O O . GLU A 1 184 ? -33.608 -0.832 -15.393 1.00 109.71 ? 184 GLU A O 1 ATOM 1398 C CB . GLU A 1 184 ? -33.963 0.868 -13.038 1.00 105.00 ? 184 GLU A CB 1 ATOM 1399 C CG . GLU A 1 184 ? -33.622 1.636 -11.769 1.00 117.12 ? 184 GLU A CG 1 ATOM 1400 C CD . GLU A 1 184 ? -34.765 2.265 -10.995 1.00 132.71 ? 184 GLU A CD 1 ATOM 1401 O OE1 . GLU A 1 184 ? -35.556 1.515 -10.377 1.00 127.70 ? 184 GLU A OE1 1 ATOM 1402 O OE2 . GLU A 1 184 ? -34.843 3.514 -10.972 1.00 114.33 ? 184 GLU A OE2 1 ATOM 1403 N N . CYS A 1 185 ? -31.383 -0.360 -15.317 1.00 110.04 ? 185 CYS A N 1 ATOM 1404 C CA . CYS A 1 185 ? -30.937 -1.444 -16.192 1.00 111.67 ? 185 CYS A CA 1 ATOM 1405 C C . CYS A 1 185 ? -30.365 -2.667 -15.469 1.00 120.15 ? 185 CYS A C 1 ATOM 1406 O O . CYS A 1 185 ? -29.698 -2.541 -14.440 1.00 119.24 ? 185 CYS A O 1 ATOM 1407 C CB . CYS A 1 185 ? -29.956 -0.905 -17.224 1.00 112.05 ? 185 CYS A CB 1 ATOM 1408 S SG . CYS A 1 185 ? -30.662 0.363 -18.307 1.00 116.02 ? 185 CYS A SG 1 ATOM 1409 N N . SER A 1 186 ? -30.615 -3.858 -16.049 1.00 120.99 ? 186 SER A N 1 ATOM 1410 C CA . SER A 1 186 ? -30.182 -5.163 -15.527 1.00 122.40 ? 186 SER A CA 1 ATOM 1411 C C . SER A 1 186 ? -29.275 -5.913 -16.543 1.00 128.32 ? 186 SER A C 1 ATOM 1412 O O . SER A 1 186 ? -29.682 -6.123 -17.696 1.00 127.60 ? 186 SER A O 1 ATOM 1413 C CB . SER A 1 186 ? -31.391 -6.020 -15.148 1.00 126.67 ? 186 SER A CB 1 ATOM 1414 O OG . SER A 1 186 ? -32.372 -5.300 -14.413 1.00 135.33 ? 186 SER A OG 1 ATOM 1415 N N . PRO A 1 187 ? -28.045 -6.321 -16.141 1.00 126.80 ? 187 PRO A N 1 ATOM 1416 C CA . PRO A 1 187 ? -27.161 -7.007 -17.103 1.00 127.10 ? 187 PRO A CA 1 ATOM 1417 C C . PRO A 1 187 ? -27.610 -8.419 -17.454 1.00 130.43 ? 187 PRO A C 1 ATOM 1418 O O . PRO A 1 187 ? -27.788 -9.258 -16.566 1.00 129.74 ? 187 PRO A O 1 ATOM 1419 C CB . PRO A 1 187 ? -25.775 -6.951 -16.441 1.00 129.01 ? 187 PRO A CB 1 ATOM 1420 C CG . PRO A 1 187 ? -26.050 -6.832 -14.990 1.00 133.31 ? 187 PRO A CG 1 ATOM 1421 C CD . PRO A 1 187 ? -27.385 -6.137 -14.829 1.00 128.75 ? 187 PRO A CD 1 ATOM 1422 N N . ARG A 1 188 ? -27.822 -8.656 -18.762 1.00 126.97 ? 188 ARG A N 1 ATOM 1423 C CA . ARG A 1 188 ? -28.281 -9.937 -19.298 1.00 127.20 ? 188 ARG A CA 1 ATOM 1424 C C . ARG A 1 188 ? -27.529 -10.372 -20.580 1.00 133.36 ? 188 ARG A C 1 ATOM 1425 O O . ARG A 1 188 ? -26.935 -9.524 -21.257 1.00 133.96 ? 188 ARG A O 1 ATOM 1426 C CB . ARG A 1 188 ? -29.805 -9.894 -19.543 1.00 126.12 ? 188 ARG A CB 1 ATOM 1427 C CG . ARG A 1 188 ? -30.656 -9.738 -18.280 1.00 132.83 ? 188 ARG A CG 1 ATOM 1428 C CD . ARG A 1 188 ? -30.597 -10.976 -17.406 1.00 138.75 ? 188 ARG A CD 1 ATOM 1429 N NE . ARG A 1 188 ? -30.737 -10.654 -15.988 1.00 144.62 ? 188 ARG A NE 1 ATOM 1430 C CZ . ARG A 1 188 ? -30.251 -11.399 -15.000 1.00 156.65 ? 188 ARG A CZ 1 ATOM 1431 N NH1 . ARG A 1 188 ? -29.569 -12.507 -15.268 1.00 144.51 ? 188 ARG A NH1 1 ATOM 1432 N NH2 . ARG A 1 188 ? -30.436 -11.039 -13.738 1.00 140.56 ? 188 ARG A NH2 1 ATOM 1433 N N . THR A 1 189 ? -27.545 -11.705 -20.883 1.00 129.92 ? 189 THR A N 1 ATOM 1434 C CA . THR A 1 189 ? -26.964 -12.398 -22.057 1.00 153.00 ? 189 THR A CA 1 ATOM 1435 C C . THR A 1 189 ? -27.524 -13.825 -22.111 1.00 156.60 ? 189 THR A C 1 ATOM 1436 O O . THR A 1 189 ? -28.732 -14.014 -22.232 1.00 109.01 ? 189 THR A O 1 ATOM 1437 C CB . THR A 1 189 ? -25.407 -12.363 -22.078 1.00 161.27 ? 189 THR A CB 1 ATOM 1438 O OG1 . THR A 1 189 ? -24.975 -11.034 -22.374 1.00 161.99 ? 189 THR A OG1 1 ATOM 1439 C CG2 . THR A 1 189 ? -24.797 -13.313 -23.125 1.00 158.44 ? 189 THR A CG2 1 ATOM 1440 N N . ASP A 1 192 ? -23.104 -15.129 -17.947 1.00 121.83 ? 192 ASP A N 1 ATOM 1441 C CA . ASP A 1 192 ? -22.974 -14.789 -16.529 1.00 121.62 ? 192 ASP A CA 1 ATOM 1442 C C . ASP A 1 192 ? -21.841 -13.791 -16.259 1.00 127.61 ? 192 ASP A C 1 ATOM 1443 O O . ASP A 1 192 ? -21.922 -13.041 -15.284 1.00 126.80 ? 192 ASP A O 1 ATOM 1444 C CB . ASP A 1 192 ? -22.848 -16.052 -15.644 1.00 122.63 ? 192 ASP A CB 1 ATOM 1445 C CG . ASP A 1 192 ? -21.575 -16.871 -15.823 1.00 125.21 ? 192 ASP A CG 1 ATOM 1446 O OD1 . ASP A 1 192 ? -20.526 -16.462 -15.286 1.00 128.45 ? 192 ASP A OD1 1 ATOM 1447 O OD2 . ASP A 1 192 ? -21.647 -17.954 -16.441 1.00 124.22 ? 192 ASP A OD2 1 ATOM 1448 N N . PHE A 1 193 ? -20.782 -13.804 -17.122 1.00 126.39 ? 193 PHE A N 1 ATOM 1449 C CA . PHE A 1 193 ? -19.556 -12.967 -17.130 1.00 127.07 ? 193 PHE A CA 1 ATOM 1450 C C . PHE A 1 193 ? -18.572 -13.205 -15.942 1.00 130.25 ? 193 PHE A C 1 ATOM 1451 O O . PHE A 1 193 ? -17.417 -12.782 -16.049 1.00 129.63 ? 193 PHE A O 1 ATOM 1452 C CB . PHE A 1 193 ? -19.857 -11.460 -17.268 1.00 129.41 ? 193 PHE A CB 1 ATOM 1453 C CG . PHE A 1 193 ? -20.795 -11.101 -18.394 1.00 131.66 ? 193 PHE A CG 1 ATOM 1454 C CD1 . PHE A 1 193 ? -20.324 -10.953 -19.693 1.00 135.30 ? 193 PHE A CD1 1 ATOM 1455 C CD2 . PHE A 1 193 ? -22.148 -10.886 -18.152 1.00 134.29 ? 193 PHE A CD2 1 ATOM 1456 C CE1 . PHE A 1 193 ? -21.195 -10.614 -20.735 1.00 136.53 ? 193 PHE A CE1 1 ATOM 1457 C CE2 . PHE A 1 193 ? -23.018 -10.546 -19.194 1.00 137.39 ? 193 PHE A CE2 1 ATOM 1458 C CZ . PHE A 1 193 ? -22.534 -10.405 -20.477 1.00 135.61 ? 193 PHE A CZ 1 ATOM 1459 N N . ASN A 1 194 ? -19.007 -13.866 -14.834 1.00 125.78 ? 194 ASN A N 1 ATOM 1460 C CA . ASN A 1 194 ? -18.118 -14.142 -13.695 1.00 124.79 ? 194 ASN A CA 1 ATOM 1461 C C . ASN A 1 194 ? -17.011 -15.054 -14.188 1.00 125.68 ? 194 ASN A C 1 ATOM 1462 O O . ASN A 1 194 ? -15.844 -14.642 -14.234 1.00 125.44 ? 194 ASN A O 1 ATOM 1463 C CB . ASN A 1 194 ? -18.833 -14.806 -12.473 1.00 125.77 ? 194 ASN A CB 1 ATOM 1464 C CG . ASN A 1 194 ? -20.335 -14.958 -12.519 1.00 137.41 ? 194 ASN A CG 1 ATOM 1465 O OD1 . ASN A 1 194 ? -21.089 -13.978 -12.499 1.00 128.88 ? 194 ASN A OD1 1 ATOM 1466 N ND2 . ASN A 1 194 ? -20.800 -16.201 -12.480 1.00 125.43 ? 194 ASN A ND2 1 ATOM 1467 N N . GLU A 1 195 ? -17.413 -16.271 -14.624 1.00 119.33 ? 195 GLU A N 1 ATOM 1468 C CA . GLU A 1 195 ? -16.549 -17.332 -15.145 1.00 117.30 ? 195 GLU A CA 1 ATOM 1469 C C . GLU A 1 195 ? -16.565 -17.343 -16.675 1.00 115.51 ? 195 GLU A C 1 ATOM 1470 O O . GLU A 1 195 ? -16.898 -18.359 -17.303 1.00 115.62 ? 195 GLU A O 1 ATOM 1471 C CB . GLU A 1 195 ? -16.923 -18.707 -14.538 1.00 118.68 ? 195 GLU A CB 1 ATOM 1472 C CG . GLU A 1 195 ? -16.993 -18.734 -13.017 1.00 130.85 ? 195 GLU A CG 1 ATOM 1473 C CD . GLU A 1 195 ? -15.845 -18.063 -12.283 1.00 154.23 ? 195 GLU A CD 1 ATOM 1474 O OE1 . GLU A 1 195 ? -14.732 -18.638 -12.261 1.00 149.47 ? 195 GLU A OE1 1 ATOM 1475 O OE2 . GLU A 1 195 ? -16.058 -16.951 -11.746 1.00 146.95 ? 195 GLU A OE2 1 ATOM 1476 N N . MET A 1 196 ? -16.221 -16.188 -17.267 1.00 106.74 ? 196 MET A N 1 ATOM 1477 C CA . MET A 1 196 ? -16.162 -16.019 -18.708 1.00 104.36 ? 196 MET A CA 1 ATOM 1478 C C . MET A 1 196 ? -14.921 -15.245 -19.111 1.00 100.28 ? 196 MET A C 1 ATOM 1479 O O . MET A 1 196 ? -14.599 -14.197 -18.535 1.00 99.29 ? 196 MET A O 1 ATOM 1480 C CB . MET A 1 196 ? -17.438 -15.358 -19.265 1.00 107.31 ? 196 MET A CB 1 ATOM 1481 C CG . MET A 1 196 ? -18.664 -16.270 -19.297 1.00 111.81 ? 196 MET A CG 1 ATOM 1482 S SD . MET A 1 196 ? -18.504 -17.766 -20.318 1.00 116.89 ? 196 MET A SD 1 ATOM 1483 C CE . MET A 1 196 ? -20.132 -18.514 -20.073 1.00 113.42 ? 196 MET A CE 1 ATOM 1484 N N . VAL A 1 197 ? -14.219 -15.804 -20.100 1.00 90.72 ? 197 VAL A N 1 ATOM 1485 C CA . VAL A 1 197 ? -13.001 -15.294 -20.710 1.00 87.48 ? 197 VAL A CA 1 ATOM 1486 C C . VAL A 1 197 ? -13.392 -14.724 -22.069 1.00 87.28 ? 197 VAL A C 1 ATOM 1487 O O . VAL A 1 197 ? -14.054 -15.392 -22.862 1.00 86.64 ? 197 VAL A O 1 ATOM 1488 C CB . VAL A 1 197 ? -11.938 -16.418 -20.862 1.00 90.22 ? 197 VAL A CB 1 ATOM 1489 C CG1 . VAL A 1 197 ? -10.670 -15.899 -21.516 1.00 89.61 ? 197 VAL A CG1 1 ATOM 1490 C CG2 . VAL A 1 197 ? -11.608 -17.059 -19.527 1.00 90.00 ? 197 VAL A CG2 1 ATOM 1491 N N . LEU A 1 198 ? -12.963 -13.501 -22.342 1.00 81.10 ? 198 LEU A N 1 ATOM 1492 C CA . LEU A 1 198 ? -13.203 -12.841 -23.611 1.00 79.63 ? 198 LEU A CA 1 ATOM 1493 C C . LEU A 1 198 ? -11.981 -13.129 -24.474 1.00 80.88 ? 198 LEU A C 1 ATOM 1494 O O . LEU A 1 198 ? -10.968 -12.415 -24.402 1.00 79.69 ? 198 LEU A O 1 ATOM 1495 C CB . LEU A 1 198 ? -13.432 -11.330 -23.373 1.00 79.71 ? 198 LEU A CB 1 ATOM 1496 C CG . LEU A 1 198 ? -13.473 -10.382 -24.574 1.00 83.66 ? 198 LEU A CG 1 ATOM 1497 C CD1 . LEU A 1 198 ? -14.776 -10.479 -25.299 1.00 83.57 ? 198 LEU A CD1 1 ATOM 1498 C CD2 . LEU A 1 198 ? -13.193 -8.960 -24.145 1.00 84.12 ? 198 LEU A CD2 1 ATOM 1499 N N . LEU A 1 199 ? -12.058 -14.223 -25.249 1.00 77.13 ? 199 LEU A N 1 ATOM 1500 C CA . LEU A 1 199 ? -10.948 -14.633 -26.103 1.00 77.31 ? 199 LEU A CA 1 ATOM 1501 C C . LEU A 1 199 ? -10.828 -13.752 -27.350 1.00 83.68 ? 199 LEU A C 1 ATOM 1502 O O . LEU A 1 199 ? -11.796 -13.642 -28.088 1.00 84.11 ? 199 LEU A O 1 ATOM 1503 C CB . LEU A 1 199 ? -11.030 -16.134 -26.449 1.00 76.81 ? 199 LEU A CB 1 ATOM 1504 C CG . LEU A 1 199 ? -10.011 -16.684 -27.470 1.00 81.04 ? 199 LEU A CG 1 ATOM 1505 C CD1 . LEU A 1 199 ? -8.592 -16.609 -26.968 1.00 80.91 ? 199 LEU A CD1 1 ATOM 1506 C CD2 . LEU A 1 199 ? -10.314 -18.100 -27.804 1.00 83.97 ? 199 LEU A CD2 1 ATOM 1507 N N . GLN A 1 200 ? -9.650 -13.128 -27.574 1.00 81.90 ? 200 GLN A N 1 ATOM 1508 C CA . GLN A 1 200 ? -9.389 -12.265 -28.732 1.00 83.44 ? 200 GLN A CA 1 ATOM 1509 C C . GLN A 1 200 ? -8.428 -12.931 -29.689 1.00 86.51 ? 200 GLN A C 1 ATOM 1510 O O . GLN A 1 200 ? -7.282 -13.198 -29.314 1.00 85.10 ? 200 GLN A O 1 ATOM 1511 C CB . GLN A 1 200 ? -8.794 -10.906 -28.326 1.00 86.15 ? 200 GLN A CB 1 ATOM 1512 C CG . GLN A 1 200 ? -9.723 -9.946 -27.594 1.00 112.61 ? 200 GLN A CG 1 ATOM 1513 C CD . GLN A 1 200 ? -9.046 -8.600 -27.467 1.00 132.80 ? 200 GLN A CD 1 ATOM 1514 O OE1 . GLN A 1 200 ? -8.873 -7.872 -28.450 1.00 130.45 ? 200 GLN A OE1 1 ATOM 1515 N NE2 . GLN A 1 200 ? -8.620 -8.239 -26.263 1.00 120.85 ? 200 GLN A NE2 1 ATOM 1516 N N . MET A 1 201 ? -8.868 -13.105 -30.943 1.00 83.84 ? 201 MET A N 1 ATOM 1517 C CA . MET A 1 201 ? -8.076 -13.743 -31.970 1.00 84.20 ? 201 MET A CA 1 ATOM 1518 C C . MET A 1 201 ? -7.264 -12.753 -32.771 1.00 91.50 ? 201 MET A C 1 ATOM 1519 O O . MET A 1 201 ? -6.105 -12.540 -32.431 1.00 91.95 ? 201 MET A O 1 ATOM 1520 C CB . MET A 1 201 ? -8.942 -14.646 -32.830 1.00 86.20 ? 201 MET A CB 1 ATOM 1521 C CG . MET A 1 201 ? -9.037 -16.048 -32.252 1.00 89.03 ? 201 MET A CG 1 ATOM 1522 S SD . MET A 1 201 ? -8.304 -17.322 -33.307 1.00 92.11 ? 201 MET A SD 1 ATOM 1523 C CE . MET A 1 201 ? -6.595 -16.642 -33.558 1.00 88.13 ? 201 MET A CE 1 ATOM 1524 N N . GLU A 1 202 ? -7.839 -12.147 -33.812 1.00 90.29 ? 202 GLU A N 1 ATOM 1525 C CA . GLU A 1 202 ? -7.160 -11.127 -34.613 1.00 91.23 ? 202 GLU A CA 1 ATOM 1526 C C . GLU A 1 202 ? -8.012 -9.862 -34.426 1.00 97.57 ? 202 GLU A C 1 ATOM 1527 O O . GLU A 1 202 ? -7.892 -9.167 -33.406 1.00 97.35 ? 202 GLU A O 1 ATOM 1528 C CB . GLU A 1 202 ? -7.094 -11.564 -36.093 1.00 92.70 ? 202 GLU A CB 1 ATOM 1529 C CG . GLU A 1 202 ? -5.734 -12.083 -36.534 1.00 107.04 ? 202 GLU A CG 1 ATOM 1530 C CD . GLU A 1 202 ? -4.677 -11.051 -36.898 1.00 128.45 ? 202 GLU A CD 1 ATOM 1531 O OE1 . GLU A 1 202 ? -5.043 -9.929 -37.328 1.00 124.09 ? 202 GLU A OE1 1 ATOM 1532 O OE2 . GLU A 1 202 ? -3.473 -11.387 -36.796 1.00 116.67 ? 202 GLU A OE2 1 ATOM 1533 N N . ASP A 1 203 ? -8.929 -9.636 -35.382 1.00 94.43 ? 203 ASP A N 1 ATOM 1534 C CA . ASP A 1 203 ? -9.960 -8.603 -35.441 1.00 93.86 ? 203 ASP A CA 1 ATOM 1535 C C . ASP A 1 203 ? -11.277 -9.303 -35.022 1.00 94.18 ? 203 ASP A C 1 ATOM 1536 O O . ASP A 1 203 ? -12.324 -8.667 -34.813 1.00 94.62 ? 203 ASP A O 1 ATOM 1537 C CB . ASP A 1 203 ? -10.061 -8.036 -36.871 1.00 96.79 ? 203 ASP A CB 1 ATOM 1538 C CG . ASP A 1 203 ? -9.851 -9.036 -38.014 1.00 117.06 ? 203 ASP A CG 1 ATOM 1539 O OD1 . ASP A 1 203 ? -10.182 -10.243 -37.830 1.00 119.57 ? 203 ASP A OD1 1 ATOM 1540 O OD2 . ASP A 1 203 ? -9.375 -8.611 -39.095 1.00 124.44 ? 203 ASP A OD2 1 ATOM 1541 N N . LYS A 1 204 ? -11.182 -10.639 -34.891 1.00 85.96 ? 204 LYS A N 1 ATOM 1542 C CA . LYS A 1 204 ? -12.243 -11.511 -34.428 1.00 83.67 ? 204 LYS A CA 1 ATOM 1543 C C . LYS A 1 204 ? -11.982 -11.712 -32.931 1.00 80.47 ? 204 LYS A C 1 ATOM 1544 O O . LYS A 1 204 ? -10.819 -11.658 -32.489 1.00 78.62 ? 204 LYS A O 1 ATOM 1545 C CB . LYS A 1 204 ? -12.222 -12.863 -35.186 1.00 87.06 ? 204 LYS A CB 1 ATOM 1546 C CG . LYS A 1 204 ? -12.697 -12.810 -36.659 1.00 102.99 ? 204 LYS A CG 1 ATOM 1547 C CD . LYS A 1 204 ? -13.004 -14.206 -37.292 1.00 110.21 ? 204 LYS A CD 1 ATOM 1548 C CE . LYS A 1 204 ? -14.313 -14.846 -36.842 1.00 113.36 ? 204 LYS A CE 1 ATOM 1549 N NZ . LYS A 1 204 ? -14.588 -16.147 -37.519 1.00 115.73 ? 204 LYS A NZ 1 ATOM 1550 N N . ALA A 1 205 ? -13.087 -11.881 -32.163 1.00 72.90 ? 205 ALA A N 1 ATOM 1551 C CA . ALA A 1 205 ? -13.157 -12.105 -30.714 1.00 70.95 ? 205 ALA A CA 1 ATOM 1552 C C . ALA A 1 205 ? -14.495 -12.749 -30.330 1.00 73.38 ? 205 ALA A C 1 ATOM 1553 O O . ALA A 1 205 ? -15.442 -12.740 -31.127 1.00 73.94 ? 205 ALA A O 1 ATOM 1554 C CB . ALA A 1 205 ? -12.951 -10.810 -29.947 1.00 71.46 ? 205 ALA A CB 1 ATOM 1555 N N . TRP A 1 206 ? -14.538 -13.401 -29.154 1.00 67.94 ? 206 TRP A N 1 ATOM 1556 C CA . TRP A 1 206 ? -15.719 -14.101 -28.641 1.00 66.92 ? 206 TRP A CA 1 ATOM 1557 C C . TRP A 1 206 ? -15.712 -14.074 -27.138 1.00 71.10 ? 206 TRP A C 1 ATOM 1558 O O . TRP A 1 206 ? -14.753 -13.618 -26.513 1.00 70.25 ? 206 TRP A O 1 ATOM 1559 C CB . TRP A 1 206 ? -15.702 -15.599 -28.980 1.00 65.42 ? 206 TRP A CB 1 ATOM 1560 C CG . TRP A 1 206 ? -15.641 -16.009 -30.410 1.00 66.04 ? 206 TRP A CG 1 ATOM 1561 C CD1 . TRP A 1 206 ? -16.547 -16.791 -31.058 1.00 68.88 ? 206 TRP A CD1 1 ATOM 1562 C CD2 . TRP A 1 206 ? -14.500 -15.917 -31.273 1.00 65.80 ? 206 TRP A CD2 1 ATOM 1563 N NE1 . TRP A 1 206 ? -16.085 -17.102 -32.315 1.00 68.45 ? 206 TRP A NE1 1 ATOM 1564 C CE2 . TRP A 1 206 ? -14.833 -16.569 -32.476 1.00 69.73 ? 206 TRP A CE2 1 ATOM 1565 C CE3 . TRP A 1 206 ? -13.215 -15.365 -31.139 1.00 67.06 ? 206 TRP A CE3 1 ATOM 1566 C CZ2 . TRP A 1 206 ? -13.961 -16.612 -33.567 1.00 69.29 ? 206 TRP A CZ2 1 ATOM 1567 C CZ3 . TRP A 1 206 ? -12.380 -15.351 -32.235 1.00 68.75 ? 206 TRP A CZ3 1 ATOM 1568 C CH2 . TRP A 1 206 ? -12.734 -16.008 -33.420 1.00 69.46 ? 206 TRP A CH2 1 ATOM 1569 N N . LEU A 1 207 ? -16.766 -14.653 -26.560 1.00 69.03 ? 207 LEU A N 1 ATOM 1570 C CA . LEU A 1 207 ? -16.882 -14.815 -25.134 1.00 69.53 ? 207 LEU A CA 1 ATOM 1571 C C . LEU A 1 207 ? -17.004 -16.264 -24.948 1.00 75.07 ? 207 LEU A C 1 ATOM 1572 O O . LEU A 1 207 ? -17.877 -16.901 -25.548 1.00 73.25 ? 207 LEU A O 1 ATOM 1573 C CB . LEU A 1 207 ? -18.074 -14.063 -24.523 1.00 69.88 ? 207 LEU A CB 1 ATOM 1574 C CG . LEU A 1 207 ? -17.770 -13.418 -23.162 1.00 74.70 ? 207 LEU A CG 1 ATOM 1575 C CD1 . LEU A 1 207 ? -17.068 -12.080 -23.325 1.00 74.63 ? 207 LEU A CD1 1 ATOM 1576 C CD2 . LEU A 1 207 ? -19.028 -13.237 -22.341 1.00 76.65 ? 207 LEU A CD2 1 ATOM 1577 N N . VAL A 1 208 ? -16.072 -16.802 -24.151 1.00 75.94 ? 208 VAL A N 1 ATOM 1578 C CA . VAL A 1 208 ? -15.944 -18.225 -23.891 1.00 76.91 ? 208 VAL A CA 1 ATOM 1579 C C . VAL A 1 208 ? -15.698 -18.586 -22.387 1.00 85.00 ? 208 VAL A C 1 ATOM 1580 O O . VAL A 1 208 ? -15.177 -17.789 -21.607 1.00 84.43 ? 208 VAL A O 1 ATOM 1581 C CB . VAL A 1 208 ? -14.861 -18.748 -24.856 1.00 79.74 ? 208 VAL A CB 1 ATOM 1582 C CG1 . VAL A 1 208 ? -13.482 -18.861 -24.216 1.00 78.90 ? 208 VAL A CG1 1 ATOM 1583 C CG2 . VAL A 1 208 ? -15.309 -20.031 -25.522 1.00 79.65 ? 208 VAL A CG2 1 ATOM 1584 N N . HIS A 1 209 ? -16.143 -19.790 -22.006 1.00 85.22 ? 209 HIS A N 1 ATOM 1585 C CA . HIS A 1 209 ? -16.053 -20.450 -20.682 1.00 86.76 ? 209 HIS A CA 1 ATOM 1586 C C . HIS A 1 209 ? -14.620 -20.405 -20.116 1.00 87.91 ? 209 HIS A C 1 ATOM 1587 O O . HIS A 1 209 ? -13.672 -20.558 -20.882 1.00 88.10 ? 209 HIS A O 1 ATOM 1588 C CB . HIS A 1 209 ? -16.517 -21.923 -20.828 1.00 89.42 ? 209 HIS A CB 1 ATOM 1589 C CG . HIS A 1 209 ? -17.307 -22.198 -22.095 1.00 94.45 ? 209 HIS A CG 1 ATOM 1590 N ND1 . HIS A 1 209 ? -16.699 -22.195 -23.360 1.00 96.68 ? 209 HIS A ND1 1 ATOM 1591 C CD2 . HIS A 1 209 ? -18.630 -22.443 -22.257 1.00 97.07 ? 209 HIS A CD2 1 ATOM 1592 C CE1 . HIS A 1 209 ? -17.667 -22.437 -24.230 1.00 96.33 ? 209 HIS A CE1 1 ATOM 1593 N NE2 . HIS A 1 209 ? -18.846 -22.588 -23.621 1.00 96.88 ? 209 HIS A NE2 1 ATOM 1594 N N . ARG A 1 210 ? -14.449 -20.184 -18.800 1.00 81.90 ? 210 ARG A N 1 ATOM 1595 C CA . ARG A 1 210 ? -13.105 -20.116 -18.178 1.00 80.08 ? 210 ARG A CA 1 ATOM 1596 C C . ARG A 1 210 ? -12.407 -21.466 -18.228 1.00 78.68 ? 210 ARG A C 1 ATOM 1597 O O . ARG A 1 210 ? -11.226 -21.544 -18.551 1.00 77.79 ? 210 ARG A O 1 ATOM 1598 C CB . ARG A 1 210 ? -13.179 -19.610 -16.726 1.00 80.69 ? 210 ARG A CB 1 ATOM 1599 C CG . ARG A 1 210 ? -11.844 -19.159 -16.120 1.00 89.71 ? 210 ARG A CG 1 ATOM 1600 C CD . ARG A 1 210 ? -11.992 -18.679 -14.673 1.00 103.08 ? 210 ARG A CD 1 ATOM 1601 N NE . ARG A 1 210 ? -12.775 -17.441 -14.560 1.00 115.58 ? 210 ARG A NE 1 ATOM 1602 C CZ . ARG A 1 210 ? -12.263 -16.240 -14.295 1.00 128.38 ? 210 ARG A CZ 1 ATOM 1603 N NH1 . ARG A 1 210 ? -10.959 -16.099 -14.077 1.00 115.22 ? 210 ARG A NH1 1 ATOM 1604 N NH2 . ARG A 1 210 ? -13.054 -15.172 -14.238 1.00 109.80 ? 210 ARG A NH2 1 ATOM 1605 N N . GLN A 1 211 ? -13.153 -22.521 -17.935 1.00 71.66 ? 211 GLN A N 1 ATOM 1606 C CA . GLN A 1 211 ? -12.647 -23.878 -17.959 1.00 69.82 ? 211 GLN A CA 1 ATOM 1607 C C . GLN A 1 211 ? -12.285 -24.344 -19.362 1.00 74.62 ? 211 GLN A C 1 ATOM 1608 O O . GLN A 1 211 ? -11.253 -24.978 -19.521 1.00 76.04 ? 211 GLN A O 1 ATOM 1609 C CB . GLN A 1 211 ? -13.640 -24.827 -17.297 1.00 69.77 ? 211 GLN A CB 1 ATOM 1610 C CG . GLN A 1 211 ? -13.735 -24.597 -15.807 1.00 55.77 ? 211 GLN A CG 1 ATOM 1611 C CD . GLN A 1 211 ? -15.034 -25.087 -15.247 1.00 85.60 ? 211 GLN A CD 1 ATOM 1612 O OE1 . GLN A 1 211 ? -15.599 -26.099 -15.688 1.00 88.13 ? 211 GLN A OE1 1 ATOM 1613 N NE2 . GLN A 1 211 ? -15.536 -24.380 -14.245 1.00 77.49 ? 211 GLN A NE2 1 ATOM 1614 N N . TRP A 1 212 ? -13.096 -24.022 -20.378 1.00 70.32 ? 212 TRP A N 1 ATOM 1615 C CA . TRP A 1 212 ? -12.809 -24.444 -21.751 1.00 70.14 ? 212 TRP A CA 1 ATOM 1616 C C . TRP A 1 212 ? -11.464 -23.863 -22.198 1.00 72.20 ? 212 TRP A C 1 ATOM 1617 O O . TRP A 1 212 ? -10.586 -24.599 -22.655 1.00 72.15 ? 212 TRP A O 1 ATOM 1618 C CB . TRP A 1 212 ? -13.959 -24.024 -22.696 1.00 69.16 ? 212 TRP A CB 1 ATOM 1619 C CG . TRP A 1 212 ? -13.781 -24.425 -24.132 1.00 70.19 ? 212 TRP A CG 1 ATOM 1620 C CD1 . TRP A 1 212 ? -14.100 -25.627 -24.689 1.00 73.37 ? 212 TRP A CD1 1 ATOM 1621 C CD2 . TRP A 1 212 ? -13.218 -23.627 -25.193 1.00 69.90 ? 212 TRP A CD2 1 ATOM 1622 N NE1 . TRP A 1 212 ? -13.750 -25.640 -26.026 1.00 73.08 ? 212 TRP A NE1 1 ATOM 1623 C CE2 . TRP A 1 212 ? -13.222 -24.421 -26.364 1.00 73.80 ? 212 TRP A CE2 1 ATOM 1624 C CE3 . TRP A 1 212 ? -12.631 -22.348 -25.249 1.00 70.94 ? 212 TRP A CE3 1 ATOM 1625 C CZ2 . TRP A 1 212 ? -12.750 -23.950 -27.594 1.00 72.76 ? 212 TRP A CZ2 1 ATOM 1626 C CZ3 . TRP A 1 212 ? -12.162 -21.880 -26.470 1.00 72.11 ? 212 TRP A CZ3 1 ATOM 1627 C CH2 . TRP A 1 212 ? -12.223 -22.678 -27.624 1.00 72.74 ? 212 TRP A CH2 1 ATOM 1628 N N . PHE A 1 213 ? -11.297 -22.554 -21.998 1.00 66.59 ? 213 PHE A N 1 ATOM 1629 C CA . PHE A 1 213 ? -10.101 -21.814 -22.358 1.00 65.16 ? 213 PHE A CA 1 ATOM 1630 C C . PHE A 1 213 ? -8.870 -22.428 -21.735 1.00 67.69 ? 213 PHE A C 1 ATOM 1631 O O . PHE A 1 213 ? -7.982 -22.876 -22.448 1.00 67.65 ? 213 PHE A O 1 ATOM 1632 C CB . PHE A 1 213 ? -10.250 -20.352 -21.917 1.00 66.30 ? 213 PHE A CB 1 ATOM 1633 C CG . PHE A 1 213 ? -9.032 -19.492 -22.108 1.00 66.72 ? 213 PHE A CG 1 ATOM 1634 C CD1 . PHE A 1 213 ? -8.704 -18.992 -23.364 1.00 67.96 ? 213 PHE A CD1 1 ATOM 1635 C CD2 . PHE A 1 213 ? -8.247 -19.129 -21.025 1.00 68.75 ? 213 PHE A CD2 1 ATOM 1636 C CE1 . PHE A 1 213 ? -7.609 -18.156 -23.539 1.00 68.58 ? 213 PHE A CE1 1 ATOM 1637 C CE2 . PHE A 1 213 ? -7.148 -18.286 -21.199 1.00 71.62 ? 213 PHE A CE2 1 ATOM 1638 C CZ . PHE A 1 213 ? -6.838 -17.806 -22.457 1.00 68.91 ? 213 PHE A CZ 1 ATOM 1639 N N . LEU A 1 214 ? -8.837 -22.467 -20.413 1.00 62.96 ? 214 LEU A N 1 ATOM 1640 C CA . LEU A 1 214 ? -7.696 -22.956 -19.642 1.00 62.63 ? 214 LEU A CA 1 ATOM 1641 C C . LEU A 1 214 ? -7.226 -24.413 -20.014 1.00 67.10 ? 214 LEU A C 1 ATOM 1642 O O . LEU A 1 214 ? -6.020 -24.712 -19.903 1.00 65.87 ? 214 LEU A O 1 ATOM 1643 C CB . LEU A 1 214 ? -7.973 -22.790 -18.135 1.00 61.68 ? 214 LEU A CB 1 ATOM 1644 C CG . LEU A 1 214 ? -8.004 -21.322 -17.672 1.00 64.15 ? 214 LEU A CG 1 ATOM 1645 C CD1 . LEU A 1 214 ? -8.530 -21.190 -16.290 1.00 63.17 ? 214 LEU A CD1 1 ATOM 1646 C CD2 . LEU A 1 214 ? -6.654 -20.673 -17.794 1.00 66.53 ? 214 LEU A CD2 1 ATOM 1647 N N . ASP A 1 215 ? -8.143 -25.254 -20.553 1.00 62.19 ? 215 ASP A N 1 ATOM 1648 C CA . ASP A 1 215 ? -7.790 -26.600 -20.959 1.00 60.49 ? 215 ASP A CA 1 ATOM 1649 C C . ASP A 1 215 ? -7.586 -26.730 -22.460 1.00 64.10 ? 215 ASP A C 1 ATOM 1650 O O . ASP A 1 215 ? -8.120 -27.643 -23.078 1.00 64.28 ? 215 ASP A O 1 ATOM 1651 C CB . ASP A 1 215 ? -8.782 -27.626 -20.418 1.00 61.72 ? 215 ASP A CB 1 ATOM 1652 C CG . ASP A 1 215 ? -8.092 -28.885 -19.954 1.00 72.70 ? 215 ASP A CG 1 ATOM 1653 O OD1 . ASP A 1 215 ? -7.083 -28.773 -19.246 1.00 72.51 ? 215 ASP A OD1 1 ATOM 1654 O OD2 . ASP A 1 215 ? -8.558 -29.991 -20.316 1.00 81.67 ? 215 ASP A OD2 1 ATOM 1655 N N . LEU A 1 216 ? -6.789 -25.840 -23.056 1.00 60.77 ? 216 LEU A N 1 ATOM 1656 C CA . LEU A 1 216 ? -6.492 -25.967 -24.489 1.00 60.63 ? 216 LEU A CA 1 ATOM 1657 C C . LEU A 1 216 ? -5.128 -26.603 -24.657 1.00 64.45 ? 216 LEU A C 1 ATOM 1658 O O . LEU A 1 216 ? -4.139 -26.144 -24.069 1.00 63.82 ? 216 LEU A O 1 ATOM 1659 C CB . LEU A 1 216 ? -6.511 -24.628 -25.290 1.00 60.50 ? 216 LEU A CB 1 ATOM 1660 C CG . LEU A 1 216 ? -7.736 -23.721 -25.236 1.00 63.33 ? 216 LEU A CG 1 ATOM 1661 C CD1 . LEU A 1 216 ? -7.520 -22.483 -26.072 1.00 62.04 ? 216 LEU A CD1 1 ATOM 1662 C CD2 . LEU A 1 216 ? -9.013 -24.460 -25.587 1.00 64.20 ? 216 LEU A CD2 1 ATOM 1663 N N . PRO A 1 217 ? -5.048 -27.614 -25.526 1.00 61.70 ? 217 PRO A N 1 ATOM 1664 C CA . PRO A 1 217 ? -3.750 -28.264 -25.798 1.00 61.90 ? 217 PRO A CA 1 ATOM 1665 C C . PRO A 1 217 ? -2.800 -27.419 -26.670 1.00 63.47 ? 217 PRO A C 1 ATOM 1666 O O . PRO A 1 217 ? -2.474 -27.832 -27.791 1.00 63.23 ? 217 PRO A O 1 ATOM 1667 C CB . PRO A 1 217 ? -4.177 -29.526 -26.543 1.00 64.05 ? 217 PRO A CB 1 ATOM 1668 C CG . PRO A 1 217 ? -5.408 -29.087 -27.298 1.00 68.17 ? 217 PRO A CG 1 ATOM 1669 C CD . PRO A 1 217 ? -6.137 -28.252 -26.289 1.00 63.39 ? 217 PRO A CD 1 ATOM 1670 N N . LEU A 1 218 ? -2.382 -26.234 -26.188 1.00 58.07 ? 218 LEU A N 1 ATOM 1671 C CA . LEU A 1 218 ? -1.501 -25.359 -26.971 1.00 57.57 ? 218 LEU A CA 1 ATOM 1672 C C . LEU A 1 218 ? -0.397 -24.712 -26.133 1.00 63.24 ? 218 LEU A C 1 ATOM 1673 O O . LEU A 1 218 ? -0.603 -24.575 -24.926 1.00 64.82 ? 218 LEU A O 1 ATOM 1674 C CB . LEU A 1 218 ? -2.312 -24.245 -27.674 1.00 56.74 ? 218 LEU A CB 1 ATOM 1675 C CG . LEU A 1 218 ? -3.384 -24.633 -28.691 1.00 58.67 ? 218 LEU A CG 1 ATOM 1676 C CD1 . LEU A 1 218 ? -4.273 -23.445 -28.991 1.00 57.68 ? 218 LEU A CD1 1 ATOM 1677 C CD2 . LEU A 1 218 ? -2.766 -25.204 -29.963 1.00 57.81 ? 218 LEU A CD2 1 ATOM 1678 N N . PRO A 1 219 ? 0.751 -24.259 -26.717 1.00 59.34 ? 219 PRO A N 1 ATOM 1679 C CA . PRO A 1 219 ? 1.765 -23.576 -25.890 1.00 59.20 ? 219 PRO A CA 1 ATOM 1680 C C . PRO A 1 219 ? 1.209 -22.267 -25.329 1.00 65.38 ? 219 PRO A C 1 ATOM 1681 O O . PRO A 1 219 ? 0.449 -21.614 -26.017 1.00 65.47 ? 219 PRO A O 1 ATOM 1682 C CB . PRO A 1 219 ? 2.946 -23.354 -26.858 1.00 60.62 ? 219 PRO A CB 1 ATOM 1683 C CG . PRO A 1 219 ? 2.677 -24.312 -28.024 1.00 65.45 ? 219 PRO A CG 1 ATOM 1684 C CD . PRO A 1 219 ? 1.184 -24.317 -28.130 1.00 61.19 ? 219 PRO A CD 1 ATOM 1685 N N . TRP A 1 220 ? 1.502 -21.931 -24.068 1.00 64.40 ? 220 TRP A N 1 ATOM 1686 C CA . TRP A 1 220 ? 0.960 -20.727 -23.454 1.00 65.90 ? 220 TRP A CA 1 ATOM 1687 C C . TRP A 1 220 ? 1.940 -19.960 -22.588 1.00 71.71 ? 220 TRP A C 1 ATOM 1688 O O . TRP A 1 220 ? 3.020 -20.438 -22.262 1.00 71.52 ? 220 TRP A O 1 ATOM 1689 C CB . TRP A 1 220 ? -0.308 -21.036 -22.663 1.00 65.41 ? 220 TRP A CB 1 ATOM 1690 C CG . TRP A 1 220 ? -0.075 -21.954 -21.507 1.00 67.28 ? 220 TRP A CG 1 ATOM 1691 C CD1 . TRP A 1 220 ? 0.014 -23.310 -21.551 1.00 70.19 ? 220 TRP A CD1 1 ATOM 1692 C CD2 . TRP A 1 220 ? 0.129 -21.581 -20.138 1.00 67.81 ? 220 TRP A CD2 1 ATOM 1693 N NE1 . TRP A 1 220 ? 0.243 -23.810 -20.293 1.00 69.91 ? 220 TRP A NE1 1 ATOM 1694 C CE2 . TRP A 1 220 ? 0.320 -22.771 -19.406 1.00 71.53 ? 220 TRP A CE2 1 ATOM 1695 C CE3 . TRP A 1 220 ? 0.192 -20.349 -19.456 1.00 69.79 ? 220 TRP A CE3 1 ATOM 1696 C CZ2 . TRP A 1 220 ? 0.527 -22.773 -18.023 1.00 71.31 ? 220 TRP A CZ2 1 ATOM 1697 C CZ3 . TRP A 1 220 ? 0.347 -20.352 -18.079 1.00 71.46 ? 220 TRP A CZ3 1 ATOM 1698 C CH2 . TRP A 1 220 ? 0.523 -21.553 -17.378 1.00 72.21 ? 220 TRP A CH2 1 ATOM 1699 N N . LEU A 1 221 ? 1.516 -18.778 -22.186 1.00 68.94 ? 221 LEU A N 1 ATOM 1700 C CA . LEU A 1 221 ? 2.275 -17.876 -21.367 1.00 69.07 ? 221 LEU A CA 1 ATOM 1701 C C . LEU A 1 221 ? 1.295 -17.268 -20.411 1.00 78.60 ? 221 LEU A C 1 ATOM 1702 O O . LEU A 1 221 ? 0.163 -16.984 -20.827 1.00 76.27 ? 221 LEU A O 1 ATOM 1703 C CB . LEU A 1 221 ? 2.897 -16.751 -22.225 1.00 68.13 ? 221 LEU A CB 1 ATOM 1704 C CG . LEU A 1 221 ? 4.183 -17.062 -22.965 1.00 71.02 ? 221 LEU A CG 1 ATOM 1705 C CD1 . LEU A 1 221 ? 4.712 -15.829 -23.677 1.00 71.16 ? 221 LEU A CD1 1 ATOM 1706 C CD2 . LEU A 1 221 ? 5.228 -17.610 -22.037 1.00 70.83 ? 221 LEU A CD2 1 ATOM 1707 N N . PRO A 1 222 ? 1.703 -17.023 -19.132 1.00 80.78 ? 222 PRO A N 1 ATOM 1708 C CA . PRO A 1 222 ? 0.767 -16.399 -18.185 1.00 81.53 ? 222 PRO A CA 1 ATOM 1709 C C . PRO A 1 222 ? 0.510 -14.934 -18.549 1.00 86.59 ? 222 PRO A C 1 ATOM 1710 O O . PRO A 1 222 ? 1.353 -14.290 -19.207 1.00 85.28 ? 222 PRO A O 1 ATOM 1711 C CB . PRO A 1 222 ? 1.479 -16.553 -16.835 1.00 83.13 ? 222 PRO A CB 1 ATOM 1712 C CG . PRO A 1 222 ? 2.554 -17.573 -17.062 1.00 86.91 ? 222 PRO A CG 1 ATOM 1713 C CD . PRO A 1 222 ? 2.984 -17.342 -18.466 1.00 82.29 ? 222 PRO A CD 1 ATOM 1714 N N . GLY A 1 223 ? -0.639 -14.425 -18.110 1.00 84.90 ? 223 GLY A N 1 ATOM 1715 C CA . GLY A 1 223 ? -1.033 -13.047 -18.370 1.00 85.84 ? 223 GLY A CA 1 ATOM 1716 C C . GLY A 1 223 ? 0.100 -12.085 -18.115 1.00 92.46 ? 223 GLY A C 1 ATOM 1717 O O . GLY A 1 223 ? 0.567 -11.407 -19.038 1.00 91.83 ? 223 GLY A O 1 ATOM 1718 N N . ALA A 1 224 ? 0.626 -12.151 -16.875 1.00 91.29 ? 224 ALA A N 1 ATOM 1719 C CA . ALA A 1 224 ? 1.739 -11.365 -16.337 1.00 91.59 ? 224 ALA A CA 1 ATOM 1720 C C . ALA A 1 224 ? 2.912 -11.182 -17.311 1.00 99.99 ? 224 ALA A C 1 ATOM 1721 O O . ALA A 1 224 ? 3.452 -10.075 -17.402 1.00 98.91 ? 224 ALA A O 1 ATOM 1722 C CB . ALA A 1 224 ? 2.226 -11.986 -15.034 1.00 91.72 ? 224 ALA A CB 1 ATOM 1723 N N . ASP A 1 225 ? 3.289 -12.249 -18.053 1.00 100.74 ? 225 ASP A N 1 ATOM 1724 C CA . ASP A 1 225 ? 4.420 -12.221 -18.976 1.00 101.92 ? 225 ASP A CA 1 ATOM 1725 C C . ASP A 1 225 ? 4.257 -11.261 -20.123 1.00 107.91 ? 225 ASP A C 1 ATOM 1726 O O . ASP A 1 225 ? 3.283 -11.340 -20.871 1.00 108.11 ? 225 ASP A O 1 ATOM 1727 C CB . ASP A 1 225 ? 4.776 -13.618 -19.504 1.00 104.16 ? 225 ASP A CB 1 ATOM 1728 C CG . ASP A 1 225 ? 6.072 -13.599 -20.298 1.00 118.19 ? 225 ASP A CG 1 ATOM 1729 O OD1 . ASP A 1 225 ? 7.154 -13.647 -19.672 1.00 119.81 ? 225 ASP A OD1 1 ATOM 1730 O OD2 . ASP A 1 225 ? 6.006 -13.450 -21.535 1.00 124.87 ? 225 ASP A OD2 1 ATOM 1731 N N . THR A 1 226 ? 5.247 -10.375 -20.267 1.00 105.95 ? 226 THR A N 1 ATOM 1732 C CA . THR A 1 226 ? 5.354 -9.396 -21.347 1.00 106.79 ? 226 THR A CA 1 ATOM 1733 C C . THR A 1 226 ? 6.750 -9.575 -22.004 1.00 111.94 ? 226 THR A C 1 ATOM 1734 O O . THR A 1 226 ? 7.125 -8.831 -22.914 1.00 111.76 ? 226 THR A O 1 ATOM 1735 C CB . THR A 1 226 ? 4.969 -7.962 -20.875 1.00 117.44 ? 226 THR A CB 1 ATOM 1736 O OG1 . THR A 1 226 ? 3.900 -8.025 -19.918 1.00 118.94 ? 226 THR A OG1 1 ATOM 1737 C CG2 . THR A 1 226 ? 4.546 -7.050 -22.036 1.00 114.77 ? 226 THR A CG2 1 ATOM 1738 N N . GLN A 1 227 ? 7.497 -10.607 -21.557 1.00 109.06 ? 227 GLN A N 1 ATOM 1739 C CA . GLN A 1 227 ? 8.800 -10.983 -22.117 1.00 109.09 ? 227 GLN A CA 1 ATOM 1740 C C . GLN A 1 227 ? 8.548 -11.548 -23.532 1.00 112.03 ? 227 GLN A C 1 ATOM 1741 O O . GLN A 1 227 ? 9.117 -11.044 -24.512 1.00 111.63 ? 227 GLN A O 1 ATOM 1742 C CB . GLN A 1 227 ? 9.528 -12.008 -21.185 1.00 110.56 ? 227 GLN A CB 1 ATOM 1743 C CG . GLN A 1 227 ? 10.622 -12.895 -21.818 1.00 123.18 ? 227 GLN A CG 1 ATOM 1744 C CD . GLN A 1 227 ? 11.778 -12.108 -22.399 1.00 143.97 ? 227 GLN A CD 1 ATOM 1745 O OE1 . GLN A 1 227 ? 11.844 -11.851 -23.609 1.00 137.46 ? 227 GLN A OE1 1 ATOM 1746 N NE2 . GLN A 1 227 ? 12.708 -11.699 -21.547 1.00 139.09 ? 227 GLN A NE2 1 ATOM 1747 N N . GLY A 1 228 ? 7.657 -12.549 -23.602 1.00 107.01 ? 228 GLY A N 1 ATOM 1748 C CA . GLY A 1 228 ? 7.263 -13.239 -24.825 1.00 105.80 ? 228 GLY A CA 1 ATOM 1749 C C . GLY A 1 228 ? 8.461 -13.811 -25.543 1.00 106.89 ? 228 GLY A C 1 ATOM 1750 O O . GLY A 1 228 ? 8.885 -13.262 -26.565 1.00 106.91 ? 228 GLY A O 1 ATOM 1751 N N . SER A 1 229 ? 9.066 -14.859 -24.963 1.00 100.42 ? 229 SER A N 1 ATOM 1752 C CA . SER A 1 229 ? 10.252 -15.487 -25.536 1.00 99.01 ? 229 SER A CA 1 ATOM 1753 C C . SER A 1 229 ? 10.185 -16.995 -25.388 1.00 99.81 ? 229 SER A C 1 ATOM 1754 O O . SER A 1 229 ? 10.433 -17.717 -26.370 1.00 100.82 ? 229 SER A O 1 ATOM 1755 C CB . SER A 1 229 ? 11.517 -14.954 -24.870 1.00 103.25 ? 229 SER A CB 1 ATOM 1756 O OG . SER A 1 229 ? 12.401 -14.359 -25.808 1.00 112.74 ? 229 SER A OG 1 ATOM 1757 N N . ASN A 1 230 ? 9.847 -17.473 -24.154 1.00 90.72 ? 230 ASN A N 1 ATOM 1758 C CA . ASN A 1 230 ? 9.777 -18.897 -23.810 1.00 86.92 ? 230 ASN A CA 1 ATOM 1759 C C . ASN A 1 230 ? 8.405 -19.310 -23.288 1.00 80.92 ? 230 ASN A C 1 ATOM 1760 O O . ASN A 1 230 ? 7.934 -18.853 -22.238 1.00 79.49 ? 230 ASN A O 1 ATOM 1761 C CB . ASN A 1 230 ? 10.897 -19.289 -22.862 1.00 89.18 ? 230 ASN A CB 1 ATOM 1762 C CG . ASN A 1 230 ? 10.909 -18.513 -21.570 1.00 115.58 ? 230 ASN A CG 1 ATOM 1763 O OD1 . ASN A 1 230 ? 10.304 -18.927 -20.562 1.00 101.65 ? 230 ASN A OD1 1 ATOM 1764 N ND2 . ASN A 1 230 ? 11.591 -17.365 -21.585 1.00 112.46 ? 230 ASN A ND2 1 ATOM 1765 N N . TRP A 1 231 ? 7.797 -20.228 -24.048 1.00 70.00 ? 231 TRP A N 1 ATOM 1766 C CA . TRP A 1 231 ? 6.443 -20.740 -23.925 1.00 65.61 ? 231 TRP A CA 1 ATOM 1767 C C . TRP A 1 231 ? 6.292 -22.032 -23.169 1.00 65.63 ? 231 TRP A C 1 ATOM 1768 O O . TRP A 1 231 ? 7.057 -22.963 -23.419 1.00 67.90 ? 231 TRP A O 1 ATOM 1769 C CB . TRP A 1 231 ? 5.956 -20.984 -25.338 1.00 63.18 ? 231 TRP A CB 1 ATOM 1770 C CG . TRP A 1 231 ? 5.746 -19.741 -26.156 1.00 63.30 ? 231 TRP A CG 1 ATOM 1771 C CD1 . TRP A 1 231 ? 6.630 -19.152 -27.017 1.00 65.77 ? 231 TRP A CD1 1 ATOM 1772 C CD2 . TRP A 1 231 ? 4.518 -19.012 -26.279 1.00 62.54 ? 231 TRP A CD2 1 ATOM 1773 N NE1 . TRP A 1 231 ? 6.030 -18.093 -27.657 1.00 64.47 ? 231 TRP A NE1 1 ATOM 1774 C CE2 . TRP A 1 231 ? 4.729 -17.992 -27.230 1.00 65.75 ? 231 TRP A CE2 1 ATOM 1775 C CE3 . TRP A 1 231 ? 3.249 -19.146 -25.693 1.00 63.32 ? 231 TRP A CE3 1 ATOM 1776 C CZ2 . TRP A 1 231 ? 3.723 -17.094 -27.590 1.00 65.00 ? 231 TRP A CZ2 1 ATOM 1777 C CZ3 . TRP A 1 231 ? 2.264 -18.245 -26.030 1.00 64.86 ? 231 TRP A CZ3 1 ATOM 1778 C CH2 . TRP A 1 231 ? 2.495 -17.247 -26.988 1.00 65.62 ? 231 TRP A CH2 1 ATOM 1779 N N . ILE A 1 232 ? 5.254 -22.141 -22.309 1.00 56.48 ? 232 ILE A N 1 ATOM 1780 C CA . ILE A 1 232 ? 4.959 -23.397 -21.588 1.00 53.15 ? 232 ILE A CA 1 ATOM 1781 C C . ILE A 1 232 ? 4.306 -24.349 -22.603 1.00 54.62 ? 232 ILE A C 1 ATOM 1782 O O . ILE A 1 232 ? 3.635 -23.862 -23.501 1.00 56.61 ? 232 ILE A O 1 ATOM 1783 C CB . ILE A 1 232 ? 4.036 -23.133 -20.371 1.00 55.13 ? 232 ILE A CB 1 ATOM 1784 C CG1 . ILE A 1 232 ? 4.697 -22.213 -19.342 1.00 54.79 ? 232 ILE A CG1 1 ATOM 1785 C CG2 . ILE A 1 232 ? 3.573 -24.433 -19.716 1.00 55.76 ? 232 ILE A CG2 1 ATOM 1786 C CD1 . ILE A 1 232 ? 3.907 -21.044 -18.998 1.00 67.43 ? 232 ILE A CD1 1 ATOM 1787 N N . GLN A 1 233 ? 4.514 -25.672 -22.487 1.00 47.64 ? 233 GLN A N 1 ATOM 1788 C CA . GLN A 1 233 ? 3.914 -26.712 -23.348 1.00 46.54 ? 233 GLN A CA 1 ATOM 1789 C C . GLN A 1 233 ? 4.299 -26.680 -24.856 1.00 49.22 ? 233 GLN A C 1 ATOM 1790 O O . GLN A 1 233 ? 3.514 -27.194 -25.651 1.00 47.75 ? 233 GLN A O 1 ATOM 1791 C CB . GLN A 1 233 ? 2.366 -26.723 -23.227 1.00 47.20 ? 233 GLN A CB 1 ATOM 1792 C CG . GLN A 1 233 ? 1.820 -27.273 -21.921 1.00 68.49 ? 233 GLN A CG 1 ATOM 1793 C CD . GLN A 1 233 ? 0.398 -26.830 -21.618 1.00 97.47 ? 233 GLN A CD 1 ATOM 1794 O OE1 . GLN A 1 233 ? 0.003 -26.719 -20.446 1.00 99.55 ? 233 GLN A OE1 1 ATOM 1795 N NE2 . GLN A 1 233 ? -0.410 -26.549 -22.646 1.00 83.80 ? 233 GLN A NE2 1 ATOM 1796 N N . LYS A 1 234 ? 5.490 -26.163 -25.257 1.00 46.34 ? 234 LYS A N 1 ATOM 1797 C CA . LYS A 1 234 ? 5.883 -26.131 -26.696 1.00 47.37 ? 234 LYS A CA 1 ATOM 1798 C C . LYS A 1 234 ? 5.603 -27.469 -27.397 1.00 55.98 ? 234 LYS A C 1 ATOM 1799 O O . LYS A 1 234 ? 5.282 -27.500 -28.589 1.00 55.94 ? 234 LYS A O 1 ATOM 1800 C CB . LYS A 1 234 ? 7.366 -25.725 -26.905 1.00 48.38 ? 234 LYS A CB 1 ATOM 1801 C CG . LYS A 1 234 ? 7.667 -24.256 -26.638 1.00 51.76 ? 234 LYS A CG 1 ATOM 1802 C CD . LYS A 1 234 ? 9.152 -23.935 -26.510 1.00 47.04 ? 234 LYS A CD 1 ATOM 1803 C CE . LYS A 1 234 ? 9.570 -24.022 -25.054 1.00 64.55 ? 234 LYS A CE 1 ATOM 1804 N NZ . LYS A 1 234 ? 9.866 -22.678 -24.482 1.00 73.24 ? 234 LYS A NZ 1 ATOM 1805 N N . GLU A 1 235 ? 5.694 -28.567 -26.620 1.00 55.26 ? 235 GLU A N 1 ATOM 1806 C CA . GLU A 1 235 ? 5.469 -29.973 -26.971 1.00 56.27 ? 235 GLU A CA 1 ATOM 1807 C C . GLU A 1 235 ? 4.149 -30.195 -27.726 1.00 63.71 ? 235 GLU A C 1 ATOM 1808 O O . GLU A 1 235 ? 4.006 -31.183 -28.462 1.00 64.43 ? 235 GLU A O 1 ATOM 1809 C CB . GLU A 1 235 ? 5.445 -30.822 -25.682 1.00 57.46 ? 235 GLU A CB 1 ATOM 1810 C CG . GLU A 1 235 ? 6.732 -30.747 -24.880 1.00 73.21 ? 235 GLU A CG 1 ATOM 1811 C CD . GLU A 1 235 ? 6.833 -29.628 -23.861 1.00 101.96 ? 235 GLU A CD 1 ATOM 1812 O OE1 . GLU A 1 235 ? 5.842 -29.399 -23.129 1.00 101.57 ? 235 GLU A OE1 1 ATOM 1813 O OE2 . GLU A 1 235 ? 7.925 -29.019 -23.758 1.00 95.23 ? 235 GLU A OE2 1 ATOM 1814 N N . THR A 1 236 ? 3.171 -29.295 -27.518 1.00 60.05 ? 236 THR A N 1 ATOM 1815 C CA . THR A 1 236 ? 1.852 -29.399 -28.136 1.00 59.12 ? 236 THR A CA 1 ATOM 1816 C C . THR A 1 236 ? 1.906 -29.025 -29.620 1.00 63.42 ? 236 THR A C 1 ATOM 1817 O O . THR A 1 236 ? 0.993 -29.382 -30.348 1.00 62.46 ? 236 THR A O 1 ATOM 1818 C CB . THR A 1 236 ? 0.811 -28.621 -27.316 1.00 56.27 ? 236 THR A CB 1 ATOM 1819 O OG1 . THR A 1 236 ? 1.179 -27.244 -27.331 1.00 56.92 ? 236 THR A OG1 1 ATOM 1820 C CG2 . THR A 1 236 ? 0.713 -29.116 -25.876 1.00 43.08 ? 236 THR A CG2 1 ATOM 1821 N N . LEU A 1 237 ? 2.966 -28.343 -30.072 1.00 62.18 ? 237 LEU A N 1 ATOM 1822 C CA . LEU A 1 237 ? 3.111 -27.968 -31.477 1.00 64.12 ? 237 LEU A CA 1 ATOM 1823 C C . LEU A 1 237 ? 4.366 -28.567 -32.067 1.00 74.10 ? 237 LEU A C 1 ATOM 1824 O O . LEU A 1 237 ? 4.575 -28.472 -33.275 1.00 73.89 ? 237 LEU A O 1 ATOM 1825 C CB . LEU A 1 237 ? 3.126 -26.420 -31.673 1.00 64.04 ? 237 LEU A CB 1 ATOM 1826 C CG . LEU A 1 237 ? 1.810 -25.599 -31.558 1.00 66.95 ? 237 LEU A CG 1 ATOM 1827 C CD1 . LEU A 1 237 ? 1.920 -24.318 -32.316 1.00 66.69 ? 237 LEU A CD1 1 ATOM 1828 C CD2 . LEU A 1 237 ? 0.587 -26.362 -32.068 1.00 66.41 ? 237 LEU A CD2 1 ATOM 1829 N N . VAL A 1 238 ? 5.235 -29.141 -31.215 1.00 75.36 ? 238 VAL A N 1 ATOM 1830 C CA . VAL A 1 238 ? 6.527 -29.729 -31.629 1.00 76.25 ? 238 VAL A CA 1 ATOM 1831 C C . VAL A 1 238 ? 6.508 -31.255 -31.518 1.00 82.39 ? 238 VAL A C 1 ATOM 1832 O O . VAL A 1 238 ? 5.902 -31.808 -30.599 1.00 82.05 ? 238 VAL A O 1 ATOM 1833 C CB . VAL A 1 238 ? 7.738 -29.114 -30.878 1.00 80.33 ? 238 VAL A CB 1 ATOM 1834 C CG1 . VAL A 1 238 ? 9.060 -29.480 -31.563 1.00 80.35 ? 238 VAL A CG1 1 ATOM 1835 C CG2 . VAL A 1 238 ? 7.610 -27.595 -30.784 1.00 80.30 ? 238 VAL A CG2 1 ATOM 1836 N N . THR A 1 239 ? 7.137 -31.927 -32.495 1.00 80.49 ? 239 THR A N 1 ATOM 1837 C CA . THR A 1 239 ? 7.222 -33.394 -32.586 1.00 80.11 ? 239 THR A CA 1 ATOM 1838 C C . THR A 1 239 ? 8.632 -33.825 -33.043 1.00 81.64 ? 239 THR A C 1 ATOM 1839 O O . THR A 1 239 ? 9.161 -33.273 -34.011 1.00 81.82 ? 239 THR A O 1 ATOM 1840 C CB . THR A 1 239 ? 6.111 -33.913 -33.546 1.00 90.09 ? 239 THR A CB 1 ATOM 1841 O OG1 . THR A 1 239 ? 4.826 -33.416 -33.144 1.00 96.85 ? 239 THR A OG1 1 ATOM 1842 C CG2 . THR A 1 239 ? 6.106 -35.435 -33.700 1.00 83.95 ? 239 THR A CG2 1 ATOM 1843 N N . PHE A 1 240 ? 9.230 -34.802 -32.341 1.00 74.74 ? 240 PHE A N 1 ATOM 1844 C CA . PHE A 1 240 ? 10.531 -35.354 -32.710 1.00 73.09 ? 240 PHE A CA 1 ATOM 1845 C C . PHE A 1 240 ? 10.323 -36.748 -33.360 1.00 79.55 ? 240 PHE A C 1 ATOM 1846 O O . PHE A 1 240 ? 9.593 -37.580 -32.826 1.00 78.84 ? 240 PHE A O 1 ATOM 1847 C CB . PHE A 1 240 ? 11.478 -35.398 -31.502 1.00 73.59 ? 240 PHE A CB 1 ATOM 1848 C CG . PHE A 1 240 ? 11.933 -34.049 -31.010 1.00 73.80 ? 240 PHE A CG 1 ATOM 1849 C CD1 . PHE A 1 240 ? 11.190 -33.351 -30.065 1.00 75.43 ? 240 PHE A CD1 1 ATOM 1850 C CD2 . PHE A 1 240 ? 13.115 -33.476 -31.486 1.00 75.93 ? 240 PHE A CD2 1 ATOM 1851 C CE1 . PHE A 1 240 ? 11.607 -32.097 -29.613 1.00 76.13 ? 240 PHE A CE1 1 ATOM 1852 C CE2 . PHE A 1 240 ? 13.543 -32.226 -31.020 1.00 78.66 ? 240 PHE A CE2 1 ATOM 1853 C CZ . PHE A 1 240 ? 12.777 -31.542 -30.093 1.00 76.30 ? 240 PHE A CZ 1 ATOM 1854 N N . LYS A 1 241 ? 10.940 -36.987 -34.504 1.00 78.96 ? 241 LYS A N 1 ATOM 1855 C CA . LYS A 1 241 ? 10.828 -38.258 -35.216 1.00 80.09 ? 241 LYS A CA 1 ATOM 1856 C C . LYS A 1 241 ? 12.192 -38.980 -35.439 1.00 85.74 ? 241 LYS A C 1 ATOM 1857 O O . LYS A 1 241 ? 13.106 -38.432 -36.049 1.00 84.82 ? 241 LYS A O 1 ATOM 1858 C CB . LYS A 1 241 ? 10.035 -38.124 -36.553 1.00 82.94 ? 241 LYS A CB 1 ATOM 1859 C CG . LYS A 1 241 ? 9.882 -36.732 -37.208 1.00 95.50 ? 241 LYS A CG 1 ATOM 1860 C CD . LYS A 1 241 ? 9.214 -36.834 -38.598 1.00 105.50 ? 241 LYS A CD 1 ATOM 1861 C CE . LYS A 1 241 ? 10.021 -36.229 -39.758 1.00 107.13 ? 241 LYS A CE 1 ATOM 1862 N NZ . LYS A 1 241 ? 9.363 -36.368 -41.085 1.00 105.14 ? 241 LYS A NZ 1 ATOM 1863 N N . ASN A 1 242 ? 12.281 -40.224 -34.992 1.00 84.16 ? 242 ASN A N 1 ATOM 1864 C CA . ASN A 1 242 ? 13.455 -41.083 -35.201 1.00 84.40 ? 242 ASN A CA 1 ATOM 1865 C C . ASN A 1 242 ? 12.958 -42.525 -35.444 1.00 89.95 ? 242 ASN A C 1 ATOM 1866 O O . ASN A 1 242 ? 12.980 -43.357 -34.529 1.00 90.10 ? 242 ASN A O 1 ATOM 1867 C CB . ASN A 1 242 ? 14.425 -40.994 -34.020 1.00 81.55 ? 242 ASN A CB 1 ATOM 1868 C CG . ASN A 1 242 ? 15.736 -41.712 -34.213 1.00 81.52 ? 242 ASN A CG 1 ATOM 1869 O OD1 . ASN A 1 242 ? 16.067 -42.199 -35.296 1.00 76.53 ? 242 ASN A OD1 1 ATOM 1870 N ND2 . ASN A 1 242 ? 16.529 -41.751 -33.162 1.00 69.36 ? 242 ASN A ND2 1 ATOM 1871 N N . PRO A 1 243 ? 12.462 -42.829 -36.660 1.00 87.49 ? 243 PRO A N 1 ATOM 1872 C CA . PRO A 1 243 ? 11.878 -44.156 -36.894 1.00 88.16 ? 243 PRO A CA 1 ATOM 1873 C C . PRO A 1 243 ? 12.842 -45.297 -37.208 1.00 94.49 ? 243 PRO A C 1 ATOM 1874 O O . PRO A 1 243 ? 12.467 -46.458 -37.027 1.00 94.83 ? 243 PRO A O 1 ATOM 1875 C CB . PRO A 1 243 ? 10.919 -43.907 -38.066 1.00 89.87 ? 243 PRO A CB 1 ATOM 1876 C CG . PRO A 1 243 ? 11.513 -42.795 -38.817 1.00 93.78 ? 243 PRO A CG 1 ATOM 1877 C CD . PRO A 1 243 ? 12.319 -41.962 -37.847 1.00 89.25 ? 243 PRO A CD 1 ATOM 1878 N N . HIS A 1 244 ? 14.045 -44.989 -37.712 1.00 92.23 ? 244 HIS A N 1 ATOM 1879 C CA . HIS A 1 244 ? 14.973 -46.036 -38.121 1.00 92.72 ? 244 HIS A CA 1 ATOM 1880 C C . HIS A 1 244 ? 16.326 -45.992 -37.409 1.00 93.39 ? 244 HIS A C 1 ATOM 1881 O O . HIS A 1 244 ? 17.261 -46.697 -37.818 1.00 93.39 ? 244 HIS A O 1 ATOM 1882 C CB . HIS A 1 244 ? 15.140 -46.001 -39.656 1.00 94.77 ? 244 HIS A CB 1 ATOM 1883 C CG . HIS A 1 244 ? 13.840 -46.018 -40.417 1.00 99.13 ? 244 HIS A CG 1 ATOM 1884 N ND1 . HIS A 1 244 ? 12.913 -47.049 -40.258 1.00 101.35 ? 244 HIS A ND1 1 ATOM 1885 C CD2 . HIS A 1 244 ? 13.363 -45.142 -41.334 1.00 101.45 ? 244 HIS A CD2 1 ATOM 1886 C CE1 . HIS A 1 244 ? 11.910 -46.760 -41.074 1.00 101.02 ? 244 HIS A CE1 1 ATOM 1887 N NE2 . HIS A 1 244 ? 12.132 -45.625 -41.745 1.00 101.36 ? 244 HIS A NE2 1 ATOM 1888 N N . ALA A 1 245 ? 16.422 -45.190 -36.325 1.00 86.94 ? 245 ALA A N 1 ATOM 1889 C CA . ALA A 1 245 ? 17.655 -44.971 -35.547 1.00 85.36 ? 245 ALA A CA 1 ATOM 1890 C C . ALA A 1 245 ? 18.808 -44.454 -36.440 1.00 84.77 ? 245 ALA A C 1 ATOM 1891 O O . ALA A 1 245 ? 19.975 -44.712 -36.161 1.00 83.31 ? 245 ALA A O 1 ATOM 1892 C CB . ALA A 1 245 ? 18.059 -46.230 -34.781 1.00 86.22 ? 245 ALA A CB 1 ATOM 1893 N N . LYS A 1 246 ? 18.460 -43.709 -37.511 1.00 79.23 ? 246 LYS A N 1 ATOM 1894 C CA . LYS A 1 246 ? 19.414 -43.139 -38.463 1.00 78.18 ? 246 LYS A CA 1 ATOM 1895 C C . LYS A 1 246 ? 19.583 -41.629 -38.215 1.00 82.79 ? 246 LYS A C 1 ATOM 1896 O O . LYS A 1 246 ? 20.682 -41.079 -38.392 1.00 82.98 ? 246 LYS A O 1 ATOM 1897 C CB . LYS A 1 246 ? 18.974 -43.405 -39.917 1.00 79.86 ? 246 LYS A CB 1 ATOM 1898 C CG . LYS A 1 246 ? 18.741 -44.873 -40.268 1.00 94.40 ? 246 LYS A CG 1 ATOM 1899 C CD . LYS A 1 246 ? 18.337 -45.078 -41.736 1.00 109.45 ? 246 LYS A CD 1 ATOM 1900 C CE . LYS A 1 246 ? 18.178 -46.549 -42.092 1.00 123.96 ? 246 LYS A CE 1 ATOM 1901 N NZ . LYS A 1 246 ? 17.967 -46.774 -43.555 1.00 128.32 ? 246 LYS A NZ 1 ATOM 1902 N N . LYS A 1 247 ? 18.481 -40.959 -37.806 1.00 79.20 ? 247 LYS A N 1 ATOM 1903 C CA . LYS A 1 247 ? 18.447 -39.518 -37.537 1.00 78.97 ? 247 LYS A CA 1 ATOM 1904 C C . LYS A 1 247 ? 17.190 -39.115 -36.743 1.00 81.67 ? 247 LYS A C 1 ATOM 1905 O O . LYS A 1 247 ? 16.147 -39.788 -36.830 1.00 81.25 ? 247 LYS A O 1 ATOM 1906 C CB . LYS A 1 247 ? 18.517 -38.721 -38.860 1.00 81.66 ? 247 LYS A CB 1 ATOM 1907 C CG . LYS A 1 247 ? 19.102 -37.323 -38.718 1.00 102.82 ? 247 LYS A CG 1 ATOM 1908 C CD . LYS A 1 247 ? 18.404 -36.346 -39.668 1.00 114.38 ? 247 LYS A CD 1 ATOM 1909 C CE . LYS A 1 247 ? 18.525 -34.895 -39.244 1.00 113.12 ? 247 LYS A CE 1 ATOM 1910 N NZ . LYS A 1 247 ? 17.609 -34.020 -40.028 1.00 114.95 ? 247 LYS A NZ 1 ATOM 1911 N N . GLN A 1 248 ? 17.302 -37.983 -36.006 1.00 77.03 ? 248 GLN A N 1 ATOM 1912 C CA . GLN A 1 248 ? 16.209 -37.357 -35.241 1.00 76.14 ? 248 GLN A CA 1 ATOM 1913 C C . GLN A 1 248 ? 15.697 -36.047 -35.947 1.00 82.32 ? 248 GLN A C 1 ATOM 1914 O O . GLN A 1 248 ? 16.452 -35.068 -36.067 1.00 82.64 ? 248 GLN A O 1 ATOM 1915 C CB . GLN A 1 248 ? 16.632 -37.116 -33.787 1.00 75.61 ? 248 GLN A CB 1 ATOM 1916 C CG . GLN A 1 248 ? 15.650 -36.287 -33.021 1.00 41.49 ? 248 GLN A CG 1 ATOM 1917 C CD . GLN A 1 248 ? 15.551 -36.729 -31.598 1.00 65.37 ? 248 GLN A CD 1 ATOM 1918 O OE1 . GLN A 1 248 ? 14.708 -37.598 -31.248 1.00 61.33 ? 248 GLN A OE1 1 ATOM 1919 N NE2 . GLN A 1 248 ? 16.395 -36.116 -30.745 1.00 52.23 ? 248 GLN A NE2 1 ATOM 1920 N N . ASP A 1 249 ? 14.418 -36.057 -36.416 1.00 78.91 ? 249 ASP A N 1 ATOM 1921 C CA . ASP A 1 249 ? 13.779 -34.960 -37.137 1.00 78.65 ? 249 ASP A CA 1 ATOM 1922 C C . ASP A 1 249 ? 12.807 -34.186 -36.283 1.00 79.60 ? 249 ASP A C 1 ATOM 1923 O O . ASP A 1 249 ? 11.999 -34.776 -35.584 1.00 78.31 ? 249 ASP A O 1 ATOM 1924 C CB . ASP A 1 249 ? 13.120 -35.464 -38.430 1.00 81.50 ? 249 ASP A CB 1 ATOM 1925 C CG . ASP A 1 249 ? 14.126 -35.700 -39.545 1.00 105.56 ? 249 ASP A CG 1 ATOM 1926 O OD1 . ASP A 1 249 ? 15.070 -36.490 -39.335 1.00 108.85 ? 249 ASP A OD1 1 ATOM 1927 O OD2 . ASP A 1 249 ? 13.998 -35.059 -40.610 1.00 116.81 ? 249 ASP A OD2 1 ATOM 1928 N N . VAL A 1 250 ? 12.887 -32.859 -36.334 1.00 75.71 ? 250 VAL A N 1 ATOM 1929 C CA . VAL A 1 250 ? 12.014 -31.996 -35.545 1.00 75.71 ? 250 VAL A CA 1 ATOM 1930 C C . VAL A 1 250 ? 10.934 -31.327 -36.440 1.00 78.94 ? 250 VAL A C 1 ATOM 1931 O O . VAL A 1 250 ? 11.253 -30.614 -37.401 1.00 78.85 ? 250 VAL A O 1 ATOM 1932 C CB . VAL A 1 250 ? 12.840 -31.018 -34.670 1.00 80.09 ? 250 VAL A CB 1 ATOM 1933 C CG1 . VAL A 1 250 ? 13.622 -29.998 -35.501 1.00 80.21 ? 250 VAL A CG1 1 ATOM 1934 C CG2 . VAL A 1 250 ? 11.968 -30.346 -33.614 1.00 79.81 ? 250 VAL A CG2 1 ATOM 1935 N N . VAL A 1 251 ? 9.649 -31.593 -36.121 1.00 75.12 ? 251 VAL A N 1 ATOM 1936 C CA . VAL A 1 251 ? 8.513 -31.108 -36.912 1.00 75.39 ? 251 VAL A CA 1 ATOM 1937 C C . VAL A 1 251 ? 7.442 -30.234 -36.152 1.00 77.51 ? 251 VAL A C 1 ATOM 1938 O O . VAL A 1 251 ? 6.921 -30.613 -35.091 1.00 75.05 ? 251 VAL A O 1 ATOM 1939 C CB . VAL A 1 251 ? 7.825 -32.290 -37.650 1.00 79.86 ? 251 VAL A CB 1 ATOM 1940 C CG1 . VAL A 1 251 ? 8.692 -32.842 -38.768 1.00 79.72 ? 251 VAL A CG1 1 ATOM 1941 C CG2 . VAL A 1 251 ? 7.387 -33.397 -36.687 1.00 79.43 ? 251 VAL A CG2 1 ATOM 1942 N N . VAL A 1 252 ? 7.108 -29.069 -36.781 1.00 74.40 ? 252 VAL A N 1 ATOM 1943 C CA . VAL A 1 252 ? 6.078 -28.100 -36.360 1.00 74.37 ? 252 VAL A CA 1 ATOM 1944 C C . VAL A 1 252 ? 4.708 -28.714 -36.692 1.00 75.78 ? 252 VAL A C 1 ATOM 1945 O O . VAL A 1 252 ? 4.578 -29.425 -37.683 1.00 74.52 ? 252 VAL A O 1 ATOM 1946 C CB . VAL A 1 252 ? 6.217 -26.706 -37.036 1.00 79.40 ? 252 VAL A CB 1 ATOM 1947 C CG1 . VAL A 1 252 ? 5.598 -25.614 -36.172 1.00 79.69 ? 252 VAL A CG1 1 ATOM 1948 C CG2 . VAL A 1 252 ? 7.668 -26.367 -37.378 1.00 79.26 ? 252 VAL A CG2 1 ATOM 1949 N N . LEU A 1 253 ? 3.695 -28.453 -35.881 1.00 72.20 ? 253 LEU A N 1 ATOM 1950 C CA . LEU A 1 253 ? 2.408 -29.103 -36.074 1.00 72.74 ? 253 LEU A CA 1 ATOM 1951 C C . LEU A 1 253 ? 1.382 -28.348 -36.936 1.00 76.74 ? 253 LEU A C 1 ATOM 1952 O O . LEU A 1 253 ? 0.269 -28.851 -37.111 1.00 78.76 ? 253 LEU A O 1 ATOM 1953 C CB . LEU A 1 253 ? 1.791 -29.475 -34.725 1.00 73.60 ? 253 LEU A CB 1 ATOM 1954 C CG . LEU A 1 253 ? 1.505 -30.962 -34.507 1.00 80.19 ? 253 LEU A CG 1 ATOM 1955 C CD1 . LEU A 1 253 ? 1.761 -31.354 -33.051 1.00 82.03 ? 253 LEU A CD1 1 ATOM 1956 C CD2 . LEU A 1 253 ? 0.066 -31.328 -34.931 1.00 82.51 ? 253 LEU A CD2 1 ATOM 1957 N N . GLY A 1 254 ? 1.743 -27.200 -37.497 1.00 69.98 ? 254 GLY A N 1 ATOM 1958 C CA . GLY A 1 254 ? 0.841 -26.486 -38.398 1.00 67.83 ? 254 GLY A CA 1 ATOM 1959 C C . GLY A 1 254 ? -0.196 -25.619 -37.718 1.00 65.74 ? 254 GLY A C 1 ATOM 1960 O O . GLY A 1 254 ? -0.767 -26.007 -36.687 1.00 64.19 ? 254 GLY A O 1 ATOM 1961 N N . SER A 1 255 ? -0.475 -24.449 -38.348 1.00 57.20 ? 255 SER A N 1 ATOM 1962 C CA . SER A 1 255 ? -1.377 -23.436 -37.842 1.00 54.48 ? 255 SER A CA 1 ATOM 1963 C C . SER A 1 255 ? -2.686 -23.971 -37.365 1.00 57.54 ? 255 SER A C 1 ATOM 1964 O O . SER A 1 255 ? -3.316 -24.775 -38.032 1.00 57.66 ? 255 SER A O 1 ATOM 1965 C CB . SER A 1 255 ? -1.597 -22.319 -38.842 1.00 56.26 ? 255 SER A CB 1 ATOM 1966 O OG . SER A 1 255 ? -2.239 -21.233 -38.188 1.00 63.83 ? 255 SER A OG 1 ATOM 1967 N N . GLN A 1 256 ? -3.074 -23.523 -36.175 1.00 53.68 ? 256 GLN A N 1 ATOM 1968 C CA . GLN A 1 256 ? -4.293 -23.887 -35.456 1.00 51.89 ? 256 GLN A CA 1 ATOM 1969 C C . GLN A 1 256 ? -5.360 -22.773 -35.556 1.00 53.98 ? 256 GLN A C 1 ATOM 1970 O O . GLN A 1 256 ? -6.366 -22.814 -34.841 1.00 53.55 ? 256 GLN A O 1 ATOM 1971 C CB . GLN A 1 256 ? -3.923 -24.200 -33.981 1.00 51.84 ? 256 GLN A CB 1 ATOM 1972 C CG . GLN A 1 256 ? -3.066 -25.451 -33.817 1.00 60.35 ? 256 GLN A CG 1 ATOM 1973 C CD . GLN A 1 256 ? -3.689 -26.714 -34.403 1.00 80.54 ? 256 GLN A CD 1 ATOM 1974 O OE1 . GLN A 1 256 ? -3.079 -27.375 -35.269 1.00 72.79 ? 256 GLN A OE1 1 ATOM 1975 N NE2 . GLN A 1 256 ? -4.905 -27.085 -33.946 1.00 66.27 ? 256 GLN A NE2 1 ATOM 1976 N N . GLU A 1 257 ? -5.130 -21.778 -36.439 1.00 48.81 ? 257 GLU A N 1 ATOM 1977 C CA . GLU A 1 257 ? -6.018 -20.622 -36.587 1.00 48.85 ? 257 GLU A CA 1 ATOM 1978 C C . GLU A 1 257 ? -7.434 -21.004 -36.996 1.00 55.88 ? 257 GLU A C 1 ATOM 1979 O O . GLU A 1 257 ? -8.379 -20.691 -36.254 1.00 55.86 ? 257 GLU A O 1 ATOM 1980 C CB . GLU A 1 257 ? -5.415 -19.583 -37.529 1.00 49.52 ? 257 GLU A CB 1 ATOM 1981 C CG . GLU A 1 257 ? -6.173 -18.273 -37.569 1.00 51.10 ? 257 GLU A CG 1 ATOM 1982 C CD . GLU A 1 257 ? -5.570 -17.249 -38.510 1.00 78.56 ? 257 GLU A CD 1 ATOM 1983 O OE1 . GLU A 1 257 ? -5.000 -17.658 -39.551 1.00 72.20 ? 257 GLU A OE1 1 ATOM 1984 O OE2 . GLU A 1 257 ? -5.697 -16.033 -38.221 1.00 75.04 ? 257 GLU A OE2 1 ATOM 1985 N N . GLY A 1 258 ? -7.549 -21.692 -38.142 1.00 52.79 ? 258 GLY A N 1 ATOM 1986 C CA . GLY A 1 258 ? -8.818 -22.151 -38.691 1.00 52.82 ? 258 GLY A CA 1 ATOM 1987 C C . GLY A 1 258 ? -9.441 -23.224 -37.827 1.00 58.56 ? 258 GLY A C 1 ATOM 1988 O O . GLY A 1 258 ? -10.664 -23.280 -37.683 1.00 59.19 ? 258 GLY A O 1 ATOM 1989 N N . ALA A 1 259 ? -8.581 -24.064 -37.225 1.00 55.05 ? 259 ALA A N 1 ATOM 1990 C CA . ALA A 1 259 ? -8.953 -25.131 -36.315 1.00 54.81 ? 259 ALA A CA 1 ATOM 1991 C C . ALA A 1 259 ? -9.742 -24.512 -35.162 1.00 60.79 ? 259 ALA A C 1 ATOM 1992 O O . ALA A 1 259 ? -10.857 -24.969 -34.868 1.00 60.39 ? 259 ALA A O 1 ATOM 1993 C CB . ALA A 1 259 ? -7.687 -25.810 -35.797 1.00 55.52 ? 259 ALA A CB 1 ATOM 1994 N N . MET A 1 260 ? -9.169 -23.427 -34.559 1.00 59.33 ? 260 MET A N 1 ATOM 1995 C CA . MET A 1 260 ? -9.750 -22.637 -33.477 1.00 60.08 ? 260 MET A CA 1 ATOM 1996 C C . MET A 1 260 ? -11.083 -22.057 -33.885 1.00 63.86 ? 260 MET A C 1 ATOM 1997 O O . MET A 1 260 ? -12.026 -22.255 -33.137 1.00 62.89 ? 260 MET A O 1 ATOM 1998 C CB . MET A 1 260 ? -8.802 -21.525 -33.024 1.00 63.28 ? 260 MET A CB 1 ATOM 1999 C CG . MET A 1 260 ? -7.872 -21.930 -31.880 1.00 68.53 ? 260 MET A CG 1 ATOM 2000 S SD . MET A 1 260 ? -8.672 -22.694 -30.417 1.00 74.52 ? 260 MET A SD 1 ATOM 2001 C CE . MET A 1 260 ? -9.517 -21.306 -29.725 1.00 71.50 ? 260 MET A CE 1 ATOM 2002 N N . HIS A 1 261 ? -11.189 -21.395 -35.089 1.00 61.73 ? 261 HIS A N 1 ATOM 2003 C CA . HIS A 1 261 ? -12.448 -20.807 -35.596 1.00 61.79 ? 261 HIS A CA 1 ATOM 2004 C C . HIS A 1 261 ? -13.572 -21.848 -35.634 1.00 67.26 ? 261 HIS A C 1 ATOM 2005 O O . HIS A 1 261 ? -14.686 -21.558 -35.205 1.00 66.04 ? 261 HIS A O 1 ATOM 2006 C CB . HIS A 1 261 ? -12.294 -20.163 -36.984 1.00 62.29 ? 261 HIS A CB 1 ATOM 2007 C CG . HIS A 1 261 ? -11.343 -19.006 -37.068 1.00 65.87 ? 261 HIS A CG 1 ATOM 2008 N ND1 . HIS A 1 261 ? -10.726 -18.671 -38.264 1.00 67.72 ? 261 HIS A ND1 1 ATOM 2009 C CD2 . HIS A 1 261 ? -10.932 -18.134 -36.119 1.00 67.95 ? 261 HIS A CD2 1 ATOM 2010 C CE1 . HIS A 1 261 ? -9.955 -17.628 -38.006 1.00 66.92 ? 261 HIS A CE1 1 ATOM 2011 N NE2 . HIS A 1 261 ? -10.045 -17.263 -36.729 1.00 67.46 ? 261 HIS A NE2 1 ATOM 2012 N N . THR A 1 262 ? -13.263 -23.065 -36.096 1.00 66.53 ? 262 THR A N 1 ATOM 2013 C CA . THR A 1 262 ? -14.211 -24.182 -36.161 1.00 68.07 ? 262 THR A CA 1 ATOM 2014 C C . THR A 1 262 ? -14.646 -24.605 -34.763 1.00 78.42 ? 262 THR A C 1 ATOM 2015 O O . THR A 1 262 ? -15.824 -24.881 -34.555 1.00 78.60 ? 262 THR A O 1 ATOM 2016 C CB . THR A 1 262 ? -13.602 -25.338 -36.934 1.00 69.60 ? 262 THR A CB 1 ATOM 2017 O OG1 . THR A 1 262 ? -13.243 -24.876 -38.241 1.00 68.60 ? 262 THR A OG1 1 ATOM 2018 C CG2 . THR A 1 262 ? -14.526 -26.542 -37.025 1.00 64.24 ? 262 THR A CG2 1 ATOM 2019 N N . ALA A 1 263 ? -13.701 -24.652 -33.808 1.00 79.38 ? 263 ALA A N 1 ATOM 2020 C CA . ALA A 1 263 ? -13.974 -25.008 -32.404 1.00 80.40 ? 263 ALA A CA 1 ATOM 2021 C C . ALA A 1 263 ? -14.868 -23.964 -31.737 1.00 86.14 ? 263 ALA A C 1 ATOM 2022 O O . ALA A 1 263 ? -15.669 -24.299 -30.871 1.00 85.59 ? 263 ALA A O 1 ATOM 2023 C CB . ALA A 1 263 ? -12.672 -25.122 -31.632 1.00 80.99 ? 263 ALA A CB 1 ATOM 2024 N N . LEU A 1 264 ? -14.738 -22.706 -32.173 1.00 84.19 ? 264 LEU A N 1 ATOM 2025 C CA . LEU A 1 264 ? -15.450 -21.549 -31.658 1.00 84.31 ? 264 LEU A CA 1 ATOM 2026 C C . LEU A 1 264 ? -16.783 -21.327 -32.381 1.00 93.65 ? 264 LEU A C 1 ATOM 2027 O O . LEU A 1 264 ? -17.347 -20.232 -32.255 1.00 93.82 ? 264 LEU A O 1 ATOM 2028 C CB . LEU A 1 264 ? -14.558 -20.296 -31.829 1.00 83.26 ? 264 LEU A CB 1 ATOM 2029 C CG . LEU A 1 264 ? -13.272 -20.205 -31.010 1.00 85.84 ? 264 LEU A CG 1 ATOM 2030 C CD1 . LEU A 1 264 ? -12.313 -19.214 -31.624 1.00 84.73 ? 264 LEU A CD1 1 ATOM 2031 C CD2 . LEU A 1 264 ? -13.557 -19.877 -29.564 1.00 86.57 ? 264 LEU A CD2 1 ATOM 2032 N N . THR A 1 265 ? -17.299 -22.340 -33.131 1.00 93.06 ? 265 THR A N 1 ATOM 2033 C CA . THR A 1 265 ? -18.564 -22.182 -33.864 1.00 94.00 ? 265 THR A CA 1 ATOM 2034 C C . THR A 1 265 ? -19.745 -21.985 -32.917 1.00 101.72 ? 265 THR A C 1 ATOM 2035 O O . THR A 1 265 ? -20.409 -20.950 -33.015 1.00 101.83 ? 265 THR A O 1 ATOM 2036 C CB . THR A 1 265 ? -18.770 -23.294 -34.887 1.00 97.38 ? 265 THR A CB 1 ATOM 2037 O OG1 . THR A 1 265 ? -17.903 -23.008 -35.969 1.00 97.22 ? 265 THR A OG1 1 ATOM 2038 C CG2 . THR A 1 265 ? -20.185 -23.373 -35.412 1.00 94.11 ? 265 THR A CG2 1 ATOM 2039 N N . GLY A 1 266 ? -19.961 -22.914 -31.984 1.00 100.38 ? 266 GLY A N 1 ATOM 2040 C CA . GLY A 1 266 ? -21.062 -22.800 -31.025 1.00 101.53 ? 266 GLY A CA 1 ATOM 2041 C C . GLY A 1 266 ? -21.032 -21.590 -30.095 1.00 108.38 ? 266 GLY A C 1 ATOM 2042 O O . GLY A 1 266 ? -22.070 -21.187 -29.565 1.00 107.52 ? 266 GLY A O 1 ATOM 2043 N N . ALA A 1 267 ? -19.841 -20.995 -29.904 1.00 107.28 ? 267 ALA A N 1 ATOM 2044 C CA . ALA A 1 267 ? -19.559 -19.879 -29.004 1.00 107.80 ? 267 ALA A CA 1 ATOM 2045 C C . ALA A 1 267 ? -20.168 -18.530 -29.377 1.00 112.03 ? 267 ALA A C 1 ATOM 2046 O O . ALA A 1 267 ? -20.453 -18.254 -30.547 1.00 109.88 ? 267 ALA A O 1 ATOM 2047 C CB . ALA A 1 267 ? -18.060 -19.727 -28.839 1.00 108.76 ? 267 ALA A CB 1 ATOM 2048 N N . THR A 1 268 ? -20.289 -17.671 -28.345 1.00 110.97 ? 268 THR A N 1 ATOM 2049 C CA . THR A 1 268 ? -20.831 -16.321 -28.410 1.00 111.60 ? 268 THR A CA 1 ATOM 2050 C C . THR A 1 268 ? -19.853 -15.387 -29.097 1.00 116.00 ? 268 THR A C 1 ATOM 2051 O O . THR A 1 268 ? -18.929 -14.884 -28.459 1.00 115.27 ? 268 THR A O 1 ATOM 2052 C CB . THR A 1 268 ? -21.205 -15.831 -27.003 1.00 121.68 ? 268 THR A CB 1 ATOM 2053 O OG1 . THR A 1 268 ? -22.048 -16.797 -26.373 1.00 122.68 ? 268 THR A OG1 1 ATOM 2054 C CG2 . THR A 1 268 ? -21.877 -14.466 -27.017 1.00 119.25 ? 268 THR A CG2 1 ATOM 2055 N N . GLU A 1 269 ? -20.067 -15.145 -30.394 1.00 113.49 ? 269 GLU A N 1 ATOM 2056 C CA . GLU A 1 269 ? -19.214 -14.230 -31.141 1.00 113.88 ? 269 GLU A CA 1 ATOM 2057 C C . GLU A 1 269 ? -19.574 -12.779 -30.772 1.00 117.64 ? 269 GLU A C 1 ATOM 2058 O O . GLU A 1 269 ? -20.753 -12.478 -30.531 1.00 117.19 ? 269 GLU A O 1 ATOM 2059 C CB . GLU A 1 269 ? -19.336 -14.479 -32.655 1.00 115.43 ? 269 GLU A CB 1 ATOM 2060 C CG . GLU A 1 269 ? -18.173 -13.915 -33.465 1.00 127.91 ? 269 GLU A CG 1 ATOM 2061 C CD . GLU A 1 269 ? -18.187 -14.114 -34.973 1.00 155.83 ? 269 GLU A CD 1 ATOM 2062 O OE1 . GLU A 1 269 ? -19.203 -14.608 -35.520 1.00 148.71 ? 269 GLU A OE1 1 ATOM 2063 O OE2 . GLU A 1 269 ? -17.177 -13.742 -35.614 1.00 153.52 ? 269 GLU A OE2 1 ATOM 2064 N N . ILE A 1 270 ? -18.543 -11.909 -30.682 1.00 113.64 ? 270 ILE A N 1 ATOM 2065 C CA . ILE A 1 270 ? -18.679 -10.474 -30.396 1.00 113.45 ? 270 ILE A CA 1 ATOM 2066 C C . ILE A 1 270 ? -17.807 -9.655 -31.326 1.00 118.39 ? 270 ILE A C 1 ATOM 2067 O O . ILE A 1 270 ? -16.665 -10.028 -31.594 1.00 117.68 ? 270 ILE A O 1 ATOM 2068 C CB . ILE A 1 270 ? -18.492 -10.046 -28.907 1.00 116.27 ? 270 ILE A CB 1 ATOM 2069 C CG1 . ILE A 1 270 ? -17.169 -10.526 -28.309 1.00 116.52 ? 270 ILE A CG1 1 ATOM 2070 C CG2 . ILE A 1 270 ? -19.661 -10.447 -28.034 1.00 117.36 ? 270 ILE A CG2 1 ATOM 2071 C CD1 . ILE A 1 270 ? -16.113 -9.515 -28.347 1.00 122.51 ? 270 ILE A CD1 1 ATOM 2072 N N . GLN A 1 271 ? -18.340 -8.532 -31.810 1.00 116.45 ? 271 GLN A N 1 ATOM 2073 C CA . GLN A 1 271 ? -17.586 -7.637 -32.678 1.00 116.99 ? 271 GLN A CA 1 ATOM 2074 C C . GLN A 1 271 ? -16.685 -6.822 -31.757 1.00 121.64 ? 271 GLN A C 1 ATOM 2075 O O . GLN A 1 271 ? -17.158 -6.322 -30.737 1.00 121.21 ? 271 GLN A O 1 ATOM 2076 C CB . GLN A 1 271 ? -18.535 -6.741 -33.507 1.00 118.44 ? 271 GLN A CB 1 ATOM 2077 C CG . GLN A 1 271 ? -17.878 -6.076 -34.720 1.00 136.31 ? 271 GLN A CG 1 ATOM 2078 C CD . GLN A 1 271 ? -17.710 -7.007 -35.906 1.00 157.02 ? 271 GLN A CD 1 ATOM 2079 O OE1 . GLN A 1 271 ? -16.890 -7.943 -35.897 1.00 150.23 ? 271 GLN A OE1 1 ATOM 2080 N NE2 . GLN A 1 271 ? -18.451 -6.733 -36.977 1.00 150.47 ? 271 GLN A NE2 1 ATOM 2081 N N . MET A 1 272 ? -15.387 -6.751 -32.061 1.00 118.55 ? 272 MET A N 1 ATOM 2082 C CA . MET A 1 272 ? -14.481 -6.024 -31.187 1.00 118.45 ? 272 MET A CA 1 ATOM 2083 C C . MET A 1 272 ? -13.620 -5.020 -31.893 1.00 121.49 ? 272 MET A C 1 ATOM 2084 O O . MET A 1 272 ? -13.208 -5.249 -33.031 1.00 121.63 ? 272 MET A O 1 ATOM 2085 C CB . MET A 1 272 ? -13.619 -6.985 -30.369 1.00 121.10 ? 272 MET A CB 1 ATOM 2086 C CG . MET A 1 272 ? -13.904 -6.895 -28.900 1.00 125.22 ? 272 MET A CG 1 ATOM 2087 S SD . MET A 1 272 ? -12.626 -7.637 -27.871 1.00 129.81 ? 272 MET A SD 1 ATOM 2088 C CE . MET A 1 272 ? -11.670 -6.192 -27.477 1.00 126.45 ? 272 MET A CE 1 ATOM 2089 N N . SER A 1 273 ? -13.332 -3.908 -31.200 1.00 117.22 ? 273 SER A N 1 ATOM 2090 C CA . SER A 1 273 ? -12.477 -2.828 -31.679 1.00 117.16 ? 273 SER A CA 1 ATOM 2091 C C . SER A 1 273 ? -11.955 -2.014 -30.500 1.00 121.17 ? 273 SER A C 1 ATOM 2092 O O . SER A 1 273 ? -12.746 -1.422 -29.759 1.00 120.68 ? 273 SER A O 1 ATOM 2093 C CB . SER A 1 273 ? -13.210 -1.941 -32.685 1.00 120.96 ? 273 SER A CB 1 ATOM 2094 O OG . SER A 1 273 ? -14.410 -1.416 -32.141 1.00 130.93 ? 273 SER A OG 1 ATOM 2095 N N . SER A 1 274 ? -10.618 -2.018 -30.320 1.00 118.17 ? 274 SER A N 1 ATOM 2096 C CA . SER A 1 274 ? -9.855 -1.305 -29.281 1.00 118.43 ? 274 SER A CA 1 ATOM 2097 C C . SER A 1 274 ? -10.491 -1.359 -27.836 1.00 121.98 ? 274 SER A C 1 ATOM 2098 O O . SER A 1 274 ? -10.682 -0.319 -27.183 1.00 122.01 ? 274 SER A O 1 ATOM 2099 C CB . SER A 1 274 ? -9.574 0.131 -29.720 1.00 122.05 ? 274 SER A CB 1 ATOM 2100 O OG . SER A 1 274 ? -10.778 0.854 -29.918 1.00 130.01 ? 274 SER A OG 1 ATOM 2101 N N . GLY A 1 275 ? -10.795 -2.579 -27.374 1.00 116.49 ? 275 GLY A N 1 ATOM 2102 C CA . GLY A 1 275 ? -11.356 -2.843 -26.047 1.00 115.00 ? 275 GLY A CA 1 ATOM 2103 C C . GLY A 1 275 ? -12.870 -2.867 -25.945 1.00 115.10 ? 275 GLY A C 1 ATOM 2104 O O . GLY A 1 275 ? -13.420 -3.407 -24.972 1.00 114.77 ? 275 GLY A O 1 ATOM 2105 N N . ASN A 1 276 ? -13.549 -2.275 -26.948 1.00 108.07 ? 276 ASN A N 1 ATOM 2106 C CA . ASN A 1 276 ? -15.002 -2.131 -27.002 1.00 106.05 ? 276 ASN A CA 1 ATOM 2107 C C . ASN A 1 276 ? -15.674 -3.236 -27.759 1.00 104.95 ? 276 ASN A C 1 ATOM 2108 O O . ASN A 1 276 ? -15.386 -3.433 -28.943 1.00 104.21 ? 276 ASN A O 1 ATOM 2109 C CB . ASN A 1 276 ? -15.378 -0.785 -27.589 1.00 108.14 ? 276 ASN A CB 1 ATOM 2110 C CG . ASN A 1 276 ? -14.963 0.351 -26.705 1.00 138.34 ? 276 ASN A CG 1 ATOM 2111 O OD1 . ASN A 1 276 ? -15.677 0.723 -25.768 1.00 136.36 ? 276 ASN A OD1 1 ATOM 2112 N ND2 . ASN A 1 276 ? -13.783 0.905 -26.965 1.00 129.94 ? 276 ASN A ND2 1 ATOM 2113 N N . LEU A 1 277 ? -16.591 -3.951 -27.072 1.00 98.28 ? 277 LEU A N 1 ATOM 2114 C CA . LEU A 1 277 ? -17.340 -5.077 -27.636 1.00 95.96 ? 277 LEU A CA 1 ATOM 2115 C C . LEU A 1 277 ? -18.744 -4.668 -28.090 1.00 96.51 ? 277 LEU A C 1 ATOM 2116 O O . LEU A 1 277 ? -19.683 -4.599 -27.297 1.00 96.27 ? 277 LEU A O 1 ATOM 2117 C CB . LEU A 1 277 ? -17.360 -6.352 -26.734 1.00 95.17 ? 277 LEU A CB 1 ATOM 2118 C CG . LEU A 1 277 ? -17.977 -6.292 -25.342 1.00 98.29 ? 277 LEU A CG 1 ATOM 2119 C CD1 . LEU A 1 277 ? -18.678 -7.588 -25.012 1.00 97.30 ? 277 LEU A CD1 1 ATOM 2120 C CD2 . LEU A 1 277 ? -16.931 -5.944 -24.288 1.00 101.09 ? 277 LEU A CD2 1 ATOM 2121 N N . LEU A 1 278 ? -18.875 -4.416 -29.395 1.00 89.83 ? 278 LEU A N 1 ATOM 2122 C CA . LEU A 1 278 ? -20.143 -4.068 -30.011 1.00 88.19 ? 278 LEU A CA 1 ATOM 2123 C C . LEU A 1 278 ? -20.967 -5.389 -30.197 1.00 91.36 ? 278 LEU A C 1 ATOM 2124 O O . LEU A 1 278 ? -21.297 -5.781 -31.321 1.00 90.83 ? 278 LEU A O 1 ATOM 2125 C CB . LEU A 1 278 ? -19.920 -3.251 -31.322 1.00 87.66 ? 278 LEU A CB 1 ATOM 2126 C CG . LEU A 1 278 ? -19.165 -1.866 -31.264 1.00 91.32 ? 278 LEU A CG 1 ATOM 2127 C CD1 . LEU A 1 278 ? -19.515 -1.034 -30.036 1.00 92.95 ? 278 LEU A CD1 1 ATOM 2128 C CD2 . LEU A 1 278 ? -17.674 -2.009 -31.393 1.00 91.11 ? 278 LEU A CD2 1 ATOM 2129 N N . PHE A 1 279 ? -21.244 -6.071 -29.037 1.00 87.20 ? 279 PHE A N 1 ATOM 2130 C CA . PHE A 1 279 ? -21.972 -7.312 -28.757 1.00 115.39 ? 279 PHE A CA 1 ATOM 2131 C C . PHE A 1 279 ? -22.726 -7.903 -29.930 1.00 136.25 ? 279 PHE A C 1 ATOM 2132 O O . PHE A 1 279 ? -22.144 -8.654 -30.706 1.00 100.77 ? 279 PHE A O 1 ATOM 2133 C CB . PHE A 1 279 ? -22.925 -7.065 -27.583 1.00 117.79 ? 279 PHE A CB 1 ATOM 2134 C CG . PHE A 1 279 ? -23.613 -8.253 -26.940 1.00 120.70 ? 279 PHE A CG 1 ATOM 2135 C CD1 . PHE A 1 279 ? -22.892 -9.394 -26.589 1.00 124.98 ? 279 PHE A CD1 1 ATOM 2136 C CD2 . PHE A 1 279 ? -24.952 -8.181 -26.565 1.00 123.83 ? 279 PHE A CD2 1 ATOM 2137 C CE1 . PHE A 1 279 ? -23.516 -10.472 -25.933 1.00 126.07 ? 279 PHE A CE1 1 ATOM 2138 C CE2 . PHE A 1 279 ? -25.574 -9.257 -25.907 1.00 127.00 ? 279 PHE A CE2 1 ATOM 2139 C CZ . PHE A 1 279 ? -24.854 -10.395 -25.600 1.00 125.14 ? 279 PHE A CZ 1 ATOM 2140 N N . HIS A 1 282 ? -28.296 -7.595 -24.938 1.00 111.44 ? 282 HIS A N 1 ATOM 2141 C CA . HIS A 1 282 ? -29.658 -7.927 -24.521 1.00 111.36 ? 282 HIS A CA 1 ATOM 2142 C C . HIS A 1 282 ? -29.981 -7.274 -23.172 1.00 113.01 ? 282 HIS A C 1 ATOM 2143 O O . HIS A 1 282 ? -30.760 -7.822 -22.380 1.00 113.32 ? 282 HIS A O 1 ATOM 2144 C CB . HIS A 1 282 ? -29.887 -9.456 -24.502 1.00 112.96 ? 282 HIS A CB 1 ATOM 2145 C CG . HIS A 1 282 ? -29.774 -10.102 -25.855 1.00 117.38 ? 282 HIS A CG 1 ATOM 2146 N ND1 . HIS A 1 282 ? -30.896 -10.337 -26.645 1.00 119.64 ? 282 HIS A ND1 1 ATOM 2147 C CD2 . HIS A 1 282 ? -28.673 -10.534 -26.523 1.00 119.49 ? 282 HIS A CD2 1 ATOM 2148 C CE1 . HIS A 1 282 ? -30.440 -10.896 -27.760 1.00 119.18 ? 282 HIS A CE1 1 ATOM 2149 N NE2 . HIS A 1 282 ? -29.108 -11.028 -27.737 1.00 119.38 ? 282 HIS A NE2 1 ATOM 2150 N N . LEU A 1 283 ? -29.394 -6.070 -22.943 1.00 106.39 ? 283 LEU A N 1 ATOM 2151 C CA . LEU A 1 283 ? -29.517 -5.238 -21.742 1.00 104.70 ? 283 LEU A CA 1 ATOM 2152 C C . LEU A 1 283 ? -30.964 -4.754 -21.473 1.00 107.96 ? 283 LEU A C 1 ATOM 2153 O O . LEU A 1 283 ? -31.419 -3.834 -22.144 1.00 107.30 ? 283 LEU A O 1 ATOM 2154 C CB . LEU A 1 283 ? -28.547 -4.057 -21.892 1.00 104.22 ? 283 LEU A CB 1 ATOM 2155 C CG . LEU A 1 283 ? -28.327 -3.189 -20.673 1.00 108.93 ? 283 LEU A CG 1 ATOM 2156 C CD1 . LEU A 1 283 ? -27.437 -3.880 -19.660 1.00 109.58 ? 283 LEU A CD1 1 ATOM 2157 C CD2 . LEU A 1 283 ? -27.705 -1.876 -21.058 1.00 110.73 ? 283 LEU A CD2 1 ATOM 2158 N N . LYS A 1 284 ? -31.678 -5.362 -20.488 1.00 105.29 ? 284 LYS A N 1 ATOM 2159 C CA . LYS A 1 284 ? -33.088 -5.028 -20.152 1.00 105.12 ? 284 LYS A CA 1 ATOM 2160 C C . LYS A 1 284 ? -33.244 -3.915 -19.102 1.00 109.74 ? 284 LYS A C 1 ATOM 2161 O O . LYS A 1 284 ? -32.724 -4.028 -17.990 1.00 108.60 ? 284 LYS A O 1 ATOM 2162 C CB . LYS A 1 284 ? -33.892 -6.274 -19.742 1.00 106.72 ? 284 LYS A CB 1 ATOM 2163 C CG . LYS A 1 284 ? -33.936 -7.343 -20.829 1.00 115.23 ? 284 LYS A CG 1 ATOM 2164 C CD . LYS A 1 284 ? -35.151 -8.264 -20.722 1.00 120.55 ? 284 LYS A CD 1 ATOM 2165 C CE . LYS A 1 284 ? -35.097 -9.376 -21.751 1.00 121.68 ? 284 LYS A CE 1 ATOM 2166 N NZ . LYS A 1 284 ? -36.362 -10.154 -21.809 1.00 122.65 ? 284 LYS A NZ 1 ATOM 2167 N N . CYS A 1 285 ? -33.975 -2.844 -19.466 1.00 108.07 ? 285 CYS A N 1 ATOM 2168 C CA . CYS A 1 285 ? -34.184 -1.678 -18.605 1.00 109.07 ? 285 CYS A CA 1 ATOM 2169 C C . CYS A 1 285 ? -35.638 -1.385 -18.279 1.00 110.25 ? 285 CYS A C 1 ATOM 2170 O O . CYS A 1 285 ? -36.565 -1.856 -18.946 1.00 109.58 ? 285 CYS A O 1 ATOM 2171 C CB . CYS A 1 285 ? -33.504 -0.438 -19.181 1.00 110.80 ? 285 CYS A CB 1 ATOM 2172 S SG . CYS A 1 285 ? -31.776 -0.688 -19.651 1.00 115.82 ? 285 CYS A SG 1 ATOM 2173 N N . ARG A 1 286 ? -35.810 -0.568 -17.229 1.00 104.38 ? 286 ARG A N 1 ATOM 2174 C CA . ARG A 1 286 ? -37.077 -0.030 -16.761 1.00 102.45 ? 286 ARG A CA 1 ATOM 2175 C C . ARG A 1 286 ? -36.915 1.479 -16.873 1.00 102.42 ? 286 ARG A C 1 ATOM 2176 O O . ARG A 1 286 ? -35.836 2.012 -16.558 1.00 101.91 ? 286 ARG A O 1 ATOM 2177 C CB . ARG A 1 286 ? -37.351 -0.429 -15.314 1.00 101.77 ? 286 ARG A CB 1 ATOM 2178 C CG . ARG A 1 286 ? -38.829 -0.520 -15.016 1.00 111.13 ? 286 ARG A CG 1 ATOM 2179 C CD . ARG A 1 286 ? -39.075 -1.352 -13.782 1.00 120.73 ? 286 ARG A CD 1 ATOM 2180 N NE . ARG A 1 286 ? -39.826 -2.572 -14.056 1.00 129.34 ? 286 ARG A NE 1 ATOM 2181 C CZ . ARG A 1 286 ? -41.151 -2.645 -14.048 1.00 146.75 ? 286 ARG A CZ 1 ATOM 2182 N NH1 . ARG A 1 286 ? -41.882 -1.564 -13.804 1.00 129.61 ? 286 ARG A NH1 1 ATOM 2183 N NH2 . ARG A 1 286 ? -41.757 -3.800 -14.302 1.00 138.33 ? 286 ARG A NH2 1 ATOM 2184 N N . LEU A 1 287 ? -37.956 2.164 -17.389 1.00 95.14 ? 287 LEU A N 1 ATOM 2185 C CA . LEU A 1 287 ? -37.951 3.612 -17.592 1.00 92.41 ? 287 LEU A CA 1 ATOM 2186 C C . LEU A 1 287 ? -38.952 4.327 -16.716 1.00 91.31 ? 287 LEU A C 1 ATOM 2187 O O . LEU A 1 287 ? -40.122 3.951 -16.693 1.00 90.09 ? 287 LEU A O 1 ATOM 2188 C CB . LEU A 1 287 ? -38.217 3.943 -19.057 1.00 92.12 ? 287 LEU A CB 1 ATOM 2189 C CG . LEU A 1 287 ? -37.052 3.722 -19.978 1.00 96.29 ? 287 LEU A CG 1 ATOM 2190 C CD1 . LEU A 1 287 ? -37.530 3.434 -21.342 1.00 96.39 ? 287 LEU A CD1 1 ATOM 2191 C CD2 . LEU A 1 287 ? -36.125 4.912 -19.970 1.00 98.38 ? 287 LEU A CD2 1 ATOM 2192 N N . ARG A 1 288 ? -38.485 5.355 -15.988 1.00 84.59 ? 288 ARG A N 1 ATOM 2193 C CA . ARG A 1 288 ? -39.329 6.144 -15.113 1.00 83.00 ? 288 ARG A CA 1 ATOM 2194 C C . ARG A 1 288 ? -39.692 7.376 -15.858 1.00 85.83 ? 288 ARG A C 1 ATOM 2195 O O . ARG A 1 288 ? -38.827 8.223 -16.131 1.00 84.77 ? 288 ARG A O 1 ATOM 2196 C CB . ARG A 1 288 ? -38.636 6.475 -13.795 1.00 83.12 ? 288 ARG A CB 1 ATOM 2197 N N . MET A 1 289 ? -40.973 7.459 -16.247 1.00 82.80 ? 289 MET A N 1 ATOM 2198 C CA . MET A 1 289 ? -41.432 8.599 -17.034 1.00 82.46 ? 289 MET A CA 1 ATOM 2199 C C . MET A 1 289 ? -42.285 9.594 -16.259 1.00 87.97 ? 289 MET A C 1 ATOM 2200 O O . MET A 1 289 ? -42.695 10.594 -16.831 1.00 87.99 ? 289 MET A O 1 ATOM 2201 C CB . MET A 1 289 ? -42.132 8.142 -18.313 1.00 84.34 ? 289 MET A CB 1 ATOM 2202 C CG . MET A 1 289 ? -41.184 7.482 -19.268 1.00 87.61 ? 289 MET A CG 1 ATOM 2203 S SD . MET A 1 289 ? -42.057 6.663 -20.583 1.00 91.39 ? 289 MET A SD 1 ATOM 2204 C CE . MET A 1 289 ? -41.180 7.416 -22.056 1.00 88.63 ? 289 MET A CE 1 ATOM 2205 N N . ASP A 1 290 ? -42.504 9.354 -14.956 1.00 85.88 ? 290 ASP A N 1 ATOM 2206 C CA . ASP A 1 290 ? -43.258 10.230 -14.057 1.00 85.77 ? 290 ASP A CA 1 ATOM 2207 C C . ASP A 1 290 ? -42.634 11.636 -14.027 1.00 88.87 ? 290 ASP A C 1 ATOM 2208 O O . ASP A 1 290 ? -43.368 12.621 -14.009 1.00 88.73 ? 290 ASP A O 1 ATOM 2209 C CB . ASP A 1 290 ? -43.310 9.622 -12.638 1.00 88.20 ? 290 ASP A CB 1 ATOM 2210 C CG . ASP A 1 290 ? -41.944 9.340 -11.989 1.00 103.03 ? 290 ASP A CG 1 ATOM 2211 O OD1 . ASP A 1 290 ? -41.344 8.274 -12.288 1.00 101.84 ? 290 ASP A OD1 1 ATOM 2212 O OD2 . ASP A 1 290 ? -41.487 10.175 -11.171 1.00 112.04 ? 290 ASP A OD2 1 ATOM 2213 N N . LYS A 1 291 ? -41.287 11.718 -14.085 1.00 84.65 ? 291 LYS A N 1 ATOM 2214 C CA . LYS A 1 291 ? -40.542 12.975 -14.042 1.00 84.49 ? 291 LYS A CA 1 ATOM 2215 C C . LYS A 1 291 ? -40.323 13.607 -15.442 1.00 85.47 ? 291 LYS A C 1 ATOM 2216 O O . LYS A 1 291 ? -39.760 14.702 -15.547 1.00 84.71 ? 291 LYS A O 1 ATOM 2217 C CB . LYS A 1 291 ? -39.222 12.801 -13.265 1.00 87.92 ? 291 LYS A CB 1 ATOM 2218 C CG . LYS A 1 291 ? -39.366 13.025 -11.757 1.00 98.60 ? 291 LYS A CG 1 ATOM 2219 C CD . LYS A 1 291 ? -38.043 12.705 -11.014 1.00 105.05 ? 291 LYS A CD 1 ATOM 2220 C CE . LYS A 1 291 ? -38.222 12.415 -9.532 1.00 105.09 ? 291 LYS A CE 1 ATOM 2221 N NZ . LYS A 1 291 ? -37.883 11.006 -9.145 1.00 100.99 ? 291 LYS A NZ 1 ATOM 2222 N N . LEU A 1 292 ? -40.796 12.930 -16.497 1.00 79.34 ? 292 LEU A N 1 ATOM 2223 C CA . LEU A 1 292 ? -40.745 13.427 -17.867 1.00 77.61 ? 292 LEU A CA 1 ATOM 2224 C C . LEU A 1 292 ? -41.992 14.245 -18.153 1.00 82.20 ? 292 LEU A C 1 ATOM 2225 O O . LEU A 1 292 ? -43.092 13.894 -17.717 1.00 82.72 ? 292 LEU A O 1 ATOM 2226 C CB . LEU A 1 292 ? -40.714 12.270 -18.865 1.00 77.10 ? 292 LEU A CB 1 ATOM 2227 C CG . LEU A 1 292 ? -39.367 11.766 -19.321 1.00 81.43 ? 292 LEU A CG 1 ATOM 2228 C CD1 . LEU A 1 292 ? -39.566 10.733 -20.386 1.00 80.07 ? 292 LEU A CD1 1 ATOM 2229 C CD2 . LEU A 1 292 ? -38.472 12.914 -19.843 1.00 86.05 ? 292 LEU A CD2 1 ATOM 2230 N N . GLN A 1 293 ? -41.838 15.297 -18.944 1.00 78.17 ? 293 GLN A N 1 ATOM 2231 C CA . GLN A 1 293 ? -42.938 16.188 -19.330 1.00 76.80 ? 293 GLN A CA 1 ATOM 2232 C C . GLN A 1 293 ? -42.786 16.662 -20.777 1.00 74.85 ? 293 GLN A C 1 ATOM 2233 O O . GLN A 1 293 ? -41.655 16.814 -21.267 1.00 72.61 ? 293 GLN A O 1 ATOM 2234 C CB . GLN A 1 293 ? -43.044 17.378 -18.353 1.00 78.23 ? 293 GLN A CB 1 ATOM 2235 C CG . GLN A 1 293 ? -41.721 18.129 -18.128 1.00 93.95 ? 293 GLN A CG 1 ATOM 2236 C CD . GLN A 1 293 ? -41.784 19.112 -16.989 1.00 119.52 ? 293 GLN A CD 1 ATOM 2237 O OE1 . GLN A 1 293 ? -41.730 20.327 -17.198 1.00 117.45 ? 293 GLN A OE1 1 ATOM 2238 N NE2 . GLN A 1 293 ? -41.883 18.612 -15.753 1.00 111.15 ? 293 GLN A NE2 1 ATOM 2239 N N . LEU A 1 294 ? -43.939 16.901 -21.442 1.00 67.31 ? 294 LEU A N 1 ATOM 2240 C CA . LEU A 1 294 ? -44.014 17.380 -22.820 1.00 64.99 ? 294 LEU A CA 1 ATOM 2241 C C . LEU A 1 294 ? -43.548 18.809 -22.925 1.00 66.51 ? 294 LEU A C 1 ATOM 2242 O O . LEU A 1 294 ? -44.047 19.668 -22.183 1.00 66.70 ? 294 LEU A O 1 ATOM 2243 C CB . LEU A 1 294 ? -45.449 17.307 -23.338 1.00 64.38 ? 294 LEU A CB 1 ATOM 2244 C CG . LEU A 1 294 ? -45.897 15.987 -23.857 1.00 68.19 ? 294 LEU A CG 1 ATOM 2245 C CD1 . LEU A 1 294 ? -47.387 15.983 -24.039 1.00 67.64 ? 294 LEU A CD1 1 ATOM 2246 C CD2 . LEU A 1 294 ? -45.222 15.676 -25.171 1.00 71.65 ? 294 LEU A CD2 1 ATOM 2247 N N . LYS A 1 295 ? -42.597 19.082 -23.839 1.00 60.40 ? 295 LYS A N 1 ATOM 2248 C CA . LYS A 1 295 ? -42.153 20.446 -24.028 1.00 60.09 ? 295 LYS A CA 1 ATOM 2249 C C . LYS A 1 295 ? -43.308 21.088 -24.823 1.00 65.95 ? 295 LYS A C 1 ATOM 2250 O O . LYS A 1 295 ? -43.764 20.496 -25.808 1.00 64.82 ? 295 LYS A O 1 ATOM 2251 C CB . LYS A 1 295 ? -40.873 20.511 -24.868 1.00 61.99 ? 295 LYS A CB 1 ATOM 2252 C CG . LYS A 1 295 ? -40.057 21.788 -24.655 1.00 68.51 ? 295 LYS A CG 1 ATOM 2253 C CD . LYS A 1 295 ? -39.164 22.140 -25.867 1.00 76.28 ? 295 LYS A CD 1 ATOM 2254 C CE . LYS A 1 295 ? -38.103 23.189 -25.584 1.00 83.87 ? 295 LYS A CE 1 ATOM 2255 N NZ . LYS A 1 295 ? -38.644 24.455 -24.995 1.00 90.48 ? 295 LYS A NZ 1 ATOM 2256 N N . GLY A 1 296 ? -43.866 22.189 -24.338 1.00 64.59 ? 296 GLY A N 1 ATOM 2257 C CA . GLY A 1 296 ? -44.929 22.896 -25.052 1.00 64.75 ? 296 GLY A CA 1 ATOM 2258 C C . GLY A 1 296 ? -46.392 22.525 -24.882 1.00 69.08 ? 296 GLY A C 1 ATOM 2259 O O . GLY A 1 296 ? -47.234 23.024 -25.637 1.00 68.55 ? 296 GLY A O 1 ATOM 2260 N N . MET A 1 297 ? -46.731 21.703 -23.877 1.00 65.91 ? 297 MET A N 1 ATOM 2261 C CA . MET A 1 297 ? -48.127 21.343 -23.628 1.00 66.06 ? 297 MET A CA 1 ATOM 2262 C C . MET A 1 297 ? -49.002 22.572 -23.234 1.00 69.35 ? 297 MET A C 1 ATOM 2263 O O . MET A 1 297 ? -50.230 22.522 -23.345 1.00 70.09 ? 297 MET A O 1 ATOM 2264 C CB . MET A 1 297 ? -48.226 20.182 -22.620 1.00 68.85 ? 297 MET A CB 1 ATOM 2265 C CG . MET A 1 297 ? -49.501 19.348 -22.771 1.00 74.91 ? 297 MET A CG 1 ATOM 2266 S SD . MET A 1 297 ? -50.070 18.988 -24.509 1.00 82.44 ? 297 MET A SD 1 ATOM 2267 C CE . MET A 1 297 ? -51.667 18.141 -24.197 1.00 79.22 ? 297 MET A CE 1 ATOM 2268 N N . SER A 1 298 ? -48.362 23.683 -22.843 1.00 63.95 ? 298 SER A N 1 ATOM 2269 C CA . SER A 1 298 ? -49.026 24.921 -22.474 1.00 63.19 ? 298 SER A CA 1 ATOM 2270 C C . SER A 1 298 ? -48.842 26.004 -23.536 1.00 67.18 ? 298 SER A C 1 ATOM 2271 O O . SER A 1 298 ? -49.427 27.076 -23.394 1.00 67.21 ? 298 SER A O 1 ATOM 2272 C CB . SER A 1 298 ? -48.535 25.398 -21.112 1.00 67.80 ? 298 SER A CB 1 ATOM 2273 O OG . SER A 1 298 ? -49.392 24.986 -20.059 1.00 77.40 ? 298 SER A OG 1 ATOM 2274 N N . TYR A 1 299 ? -48.052 25.734 -24.612 1.00 63.14 ? 299 TYR A N 1 ATOM 2275 C CA . TYR A 1 299 ? -47.870 26.703 -25.698 1.00 62.60 ? 299 TYR A CA 1 ATOM 2276 C C . TYR A 1 299 ? -49.159 26.777 -26.493 1.00 67.77 ? 299 TYR A C 1 ATOM 2277 O O . TYR A 1 299 ? -49.926 25.809 -26.557 1.00 66.61 ? 299 TYR A O 1 ATOM 2278 C CB . TYR A 1 299 ? -46.740 26.316 -26.681 1.00 63.47 ? 299 TYR A CB 1 ATOM 2279 C CG . TYR A 1 299 ? -45.318 26.229 -26.168 1.00 65.56 ? 299 TYR A CG 1 ATOM 2280 C CD1 . TYR A 1 299 ? -44.978 26.697 -24.896 1.00 68.22 ? 299 TYR A CD1 1 ATOM 2281 C CD2 . TYR A 1 299 ? -44.299 25.714 -26.970 1.00 65.88 ? 299 TYR A CD2 1 ATOM 2282 C CE1 . TYR A 1 299 ? -43.679 26.595 -24.416 1.00 69.33 ? 299 TYR A CE1 1 ATOM 2283 C CE2 . TYR A 1 299 ? -42.995 25.611 -26.504 1.00 66.87 ? 299 TYR A CE2 1 ATOM 2284 C CZ . TYR A 1 299 ? -42.693 26.052 -25.226 1.00 81.86 ? 299 TYR A CZ 1 ATOM 2285 O OH . TYR A 1 299 ? -41.416 25.935 -24.750 1.00 92.44 ? 299 TYR A OH 1 ATOM 2286 N N . SER A 1 300 ? -49.386 27.929 -27.124 1.00 66.04 ? 300 SER A N 1 ATOM 2287 C CA . SER A 1 300 ? -50.562 28.145 -27.945 1.00 65.40 ? 300 SER A CA 1 ATOM 2288 C C . SER A 1 300 ? -50.364 27.562 -29.337 1.00 70.21 ? 300 SER A C 1 ATOM 2289 O O . SER A 1 300 ? -49.238 27.205 -29.703 1.00 69.21 ? 300 SER A O 1 ATOM 2290 C CB . SER A 1 300 ? -50.933 29.621 -27.964 1.00 67.57 ? 300 SER A CB 1 ATOM 2291 O OG . SER A 1 300 ? -51.502 29.965 -26.707 1.00 71.81 ? 300 SER A OG 1 ATOM 2292 N N . MET A 1 301 ? -51.468 27.403 -30.088 1.00 68.13 ? 301 MET A N 1 ATOM 2293 C CA . MET A 1 301 ? -51.441 26.815 -31.425 1.00 68.88 ? 301 MET A CA 1 ATOM 2294 C C . MET A 1 301 ? -50.886 27.787 -32.445 1.00 71.99 ? 301 MET A C 1 ATOM 2295 O O . MET A 1 301 ? -51.247 28.961 -32.438 1.00 71.53 ? 301 MET A O 1 ATOM 2296 C CB . MET A 1 301 ? -52.852 26.376 -31.851 1.00 72.20 ? 301 MET A CB 1 ATOM 2297 C CG . MET A 1 301 ? -53.422 25.251 -31.014 1.00 77.04 ? 301 MET A CG 1 ATOM 2298 S SD . MET A 1 301 ? -52.551 23.694 -31.282 1.00 82.44 ? 301 MET A SD 1 ATOM 2299 C CE . MET A 1 301 ? -53.359 23.165 -32.755 1.00 79.95 ? 301 MET A CE 1 ATOM 2300 N N . CYS A 1 302 ? -50.019 27.304 -33.341 1.00 68.83 ? 302 CYS A N 1 ATOM 2301 C CA . CYS A 1 302 ? -49.467 28.131 -34.413 1.00 68.74 ? 302 CYS A CA 1 ATOM 2302 C C . CYS A 1 302 ? -50.642 28.590 -35.260 1.00 74.10 ? 302 CYS A C 1 ATOM 2303 O O . CYS A 1 302 ? -51.606 27.836 -35.430 1.00 73.34 ? 302 CYS A O 1 ATOM 2304 C CB . CYS A 1 302 ? -48.460 27.346 -35.257 1.00 68.88 ? 302 CYS A CB 1 ATOM 2305 S SG . CYS A 1 302 ? -46.938 26.854 -34.390 1.00 72.60 ? 302 CYS A SG 1 ATOM 2306 N N . THR A 1 303 ? -50.594 29.824 -35.762 1.00 73.12 ? 303 THR A N 1 ATOM 2307 C CA . THR A 1 303 ? -51.683 30.368 -36.603 1.00 73.28 ? 303 THR A CA 1 ATOM 2308 C C . THR A 1 303 ? -51.233 30.568 -38.053 1.00 77.85 ? 303 THR A C 1 ATOM 2309 O O . THR A 1 303 ? -52.064 30.539 -38.968 1.00 78.27 ? 303 THR A O 1 ATOM 2310 C CB . THR A 1 303 ? -52.317 31.642 -35.988 1.00 72.84 ? 303 THR A CB 1 ATOM 2311 O OG1 . THR A 1 303 ? -51.320 32.669 -35.836 1.00 75.01 ? 303 THR A OG1 1 ATOM 2312 C CG2 . THR A 1 303 ? -53.065 31.362 -34.664 1.00 61.63 ? 303 THR A CG2 1 ATOM 2313 N N . GLY A 1 304 ? -49.926 30.716 -38.239 1.00 74.48 ? 304 GLY A N 1 ATOM 2314 C CA . GLY A 1 304 ? -49.306 30.949 -39.531 1.00 74.97 ? 304 GLY A CA 1 ATOM 2315 C C . GLY A 1 304 ? -49.387 29.830 -40.545 1.00 80.46 ? 304 GLY A C 1 ATOM 2316 O O . GLY A 1 304 ? -50.126 28.842 -40.384 1.00 81.57 ? 304 GLY A O 1 ATOM 2317 N N . LYS A 1 305 ? -48.612 30.013 -41.621 1.00 75.82 ? 305 LYS A N 1 ATOM 2318 C CA . LYS A 1 305 ? -48.527 29.095 -42.750 1.00 74.69 ? 305 LYS A CA 1 ATOM 2319 C C . LYS A 1 305 ? -47.225 28.312 -42.691 1.00 74.22 ? 305 LYS A C 1 ATOM 2320 O O . LYS A 1 305 ? -46.232 28.799 -42.142 1.00 72.97 ? 305 LYS A O 1 ATOM 2321 C CB . LYS A 1 305 ? -48.682 29.855 -44.094 1.00 77.65 ? 305 LYS A CB 1 ATOM 2322 C CG . LYS A 1 305 ? -50.027 30.599 -44.256 1.00 84.88 ? 305 LYS A CG 1 ATOM 2323 C CD . LYS A 1 305 ? -50.171 31.168 -45.661 1.00 100.18 ? 305 LYS A CD 1 ATOM 2324 C CE . LYS A 1 305 ? -51.475 31.901 -45.874 1.00 114.27 ? 305 LYS A CE 1 ATOM 2325 N NZ . LYS A 1 305 ? -52.193 31.435 -47.095 1.00 119.42 ? 305 LYS A NZ 1 ATOM 2326 N N . PHE A 1 306 ? -47.242 27.088 -43.249 1.00 69.08 ? 306 PHE A N 1 ATOM 2327 C CA . PHE A 1 306 ? -46.090 26.177 -43.249 1.00 67.20 ? 306 PHE A CA 1 ATOM 2328 C C . PHE A 1 306 ? -45.618 25.810 -44.640 1.00 70.24 ? 306 PHE A C 1 ATOM 2329 O O . PHE A 1 306 ? -46.428 25.649 -45.537 1.00 70.45 ? 306 PHE A O 1 ATOM 2330 C CB . PHE A 1 306 ? -46.438 24.904 -42.467 1.00 67.63 ? 306 PHE A CB 1 ATOM 2331 C CG . PHE A 1 306 ? -46.660 25.122 -40.995 1.00 66.72 ? 306 PHE A CG 1 ATOM 2332 C CD1 . PHE A 1 306 ? -45.595 25.140 -40.116 1.00 68.54 ? 306 PHE A CD1 1 ATOM 2333 C CD2 . PHE A 1 306 ? -47.934 25.302 -40.491 1.00 67.19 ? 306 PHE A CD2 1 ATOM 2334 C CE1 . PHE A 1 306 ? -45.804 25.311 -38.755 1.00 71.46 ? 306 PHE A CE1 1 ATOM 2335 C CE2 . PHE A 1 306 ? -48.146 25.486 -39.132 1.00 67.60 ? 306 PHE A CE2 1 ATOM 2336 C CZ . PHE A 1 306 ? -47.081 25.505 -38.275 1.00 69.04 ? 306 PHE A CZ 1 ATOM 2337 N N . LYS A 1 307 ? -44.319 25.652 -44.806 1.00 67.10 ? 307 LYS A N 1 ATOM 2338 C CA . LYS A 1 307 ? -43.692 25.278 -46.073 1.00 68.32 ? 307 LYS A CA 1 ATOM 2339 C C . LYS A 1 307 ? -43.121 23.838 -45.958 1.00 77.76 ? 307 LYS A C 1 ATOM 2340 O O . LYS A 1 307 ? -42.768 23.403 -44.860 1.00 79.01 ? 307 LYS A O 1 ATOM 2341 C CB . LYS A 1 307 ? -42.579 26.283 -46.406 1.00 69.57 ? 307 LYS A CB 1 ATOM 2342 C CG . LYS A 1 307 ? -42.205 26.365 -47.868 1.00 84.11 ? 307 LYS A CG 1 ATOM 2343 C CD . LYS A 1 307 ? -41.057 27.355 -48.102 1.00 100.19 ? 307 LYS A CD 1 ATOM 2344 C CE . LYS A 1 307 ? -39.744 27.126 -47.347 1.00 106.01 ? 307 LYS A CE 1 ATOM 2345 N NZ . LYS A 1 307 ? -38.985 28.389 -47.131 1.00 103.80 ? 307 LYS A NZ 1 ATOM 2346 N N . ILE A 1 308 ? -43.023 23.114 -47.085 1.00 75.10 ? 308 ILE A N 1 ATOM 2347 C CA . ILE A 1 308 ? -42.572 21.718 -47.135 1.00 75.30 ? 308 ILE A CA 1 ATOM 2348 C C . ILE A 1 308 ? -41.108 21.577 -47.569 1.00 81.78 ? 308 ILE A C 1 ATOM 2349 O O . ILE A 1 308 ? -40.806 21.454 -48.755 1.00 81.60 ? 308 ILE A O 1 ATOM 2350 C CB . ILE A 1 308 ? -43.521 20.827 -47.978 1.00 78.48 ? 308 ILE A CB 1 ATOM 2351 C CG1 . ILE A 1 308 ? -44.461 21.657 -48.939 1.00 80.84 ? 308 ILE A CG1 1 ATOM 2352 C CG2 . ILE A 1 308 ? -44.335 19.968 -47.059 1.00 76.31 ? 308 ILE A CG2 1 ATOM 2353 C CD1 . ILE A 1 308 ? -43.789 22.514 -50.238 1.00 90.46 ? 308 ILE A CD1 1 ATOM 2354 N N . VAL A 1 309 ? -40.211 21.570 -46.573 1.00 80.62 ? 309 VAL A N 1 ATOM 2355 C CA . VAL A 1 309 ? -38.746 21.462 -46.668 1.00 81.21 ? 309 VAL A CA 1 ATOM 2356 C C . VAL A 1 309 ? -38.308 20.110 -47.293 1.00 85.22 ? 309 VAL A C 1 ATOM 2357 O O . VAL A 1 309 ? -37.519 20.095 -48.247 1.00 84.90 ? 309 VAL A O 1 ATOM 2358 C CB . VAL A 1 309 ? -38.131 21.693 -45.253 1.00 85.81 ? 309 VAL A CB 1 ATOM 2359 C CG1 . VAL A 1 309 ? -36.610 21.532 -45.253 1.00 85.85 ? 309 VAL A CG1 1 ATOM 2360 C CG2 . VAL A 1 309 ? -38.544 23.056 -44.677 1.00 85.64 ? 309 VAL A CG2 1 ATOM 2361 N N . LYS A 1 310 ? -38.810 18.992 -46.740 1.00 81.27 ? 310 LYS A N 1 ATOM 2362 C CA . LYS A 1 310 ? -38.510 17.653 -47.238 1.00 80.49 ? 310 LYS A CA 1 ATOM 2363 C C . LYS A 1 310 ? -39.812 16.891 -47.422 1.00 83.19 ? 310 LYS A C 1 ATOM 2364 O O . LYS A 1 310 ? -40.625 16.778 -46.479 1.00 83.50 ? 310 LYS A O 1 ATOM 2365 C CB . LYS A 1 310 ? -37.548 16.913 -46.294 1.00 82.76 ? 310 LYS A CB 1 ATOM 2366 C CG . LYS A 1 310 ? -36.610 15.938 -47.003 1.00 94.98 ? 310 LYS A CG 1 ATOM 2367 C CD . LYS A 1 310 ? -35.363 15.638 -46.152 1.00 101.31 ? 310 LYS A CD 1 ATOM 2368 C CE . LYS A 1 310 ? -34.199 15.059 -46.931 1.00 103.37 ? 310 LYS A CE 1 ATOM 2369 N NZ . LYS A 1 310 ? -33.453 16.090 -47.705 1.00 107.98 ? 310 LYS A NZ 1 ATOM 2370 N N . GLU A 1 311 ? -40.007 16.386 -48.658 1.00 76.96 ? 311 GLU A N 1 ATOM 2371 C CA . GLU A 1 311 ? -41.164 15.603 -49.095 1.00 75.81 ? 311 GLU A CA 1 ATOM 2372 C C . GLU A 1 311 ? -41.459 14.420 -48.150 1.00 77.96 ? 311 GLU A C 1 ATOM 2373 O O . GLU A 1 311 ? -40.541 13.884 -47.530 1.00 76.47 ? 311 GLU A O 1 ATOM 2374 C CB . GLU A 1 311 ? -40.904 15.095 -50.518 1.00 77.13 ? 311 GLU A CB 1 ATOM 2375 C CG . GLU A 1 311 ? -42.095 14.397 -51.158 1.00 91.45 ? 311 GLU A CG 1 ATOM 2376 C CD . GLU A 1 311 ? -41.977 14.080 -52.637 1.00 121.82 ? 311 GLU A CD 1 ATOM 2377 O OE1 . GLU A 1 311 ? -41.418 14.915 -53.384 1.00 127.88 ? 311 GLU A OE1 1 ATOM 2378 O OE2 . GLU A 1 311 ? -42.512 13.029 -53.060 1.00 113.68 ? 311 GLU A OE2 1 ATOM 2379 N N . ILE A 1 312 ? -42.741 14.024 -48.042 1.00 74.43 ? 312 ILE A N 1 ATOM 2380 C CA . ILE A 1 312 ? -43.137 12.869 -47.233 1.00 73.61 ? 312 ILE A CA 1 ATOM 2381 C C . ILE A 1 312 ? -42.340 11.676 -47.730 1.00 78.46 ? 312 ILE A C 1 ATOM 2382 O O . ILE A 1 312 ? -42.293 11.421 -48.938 1.00 78.05 ? 312 ILE A O 1 ATOM 2383 C CB . ILE A 1 312 ? -44.667 12.543 -47.258 1.00 75.87 ? 312 ILE A CB 1 ATOM 2384 C CG1 . ILE A 1 312 ? -45.544 13.772 -46.940 1.00 75.93 ? 312 ILE A CG1 1 ATOM 2385 C CG2 . ILE A 1 312 ? -44.988 11.368 -46.326 1.00 75.04 ? 312 ILE A CG2 1 ATOM 2386 C CD1 . ILE A 1 312 ? -47.076 13.518 -46.925 1.00 74.57 ? 312 ILE A CD1 1 ATOM 2387 N N . ALA A 1 313 ? -41.673 10.991 -46.792 1.00 75.67 ? 313 ALA A N 1 ATOM 2388 C CA . ALA A 1 313 ? -40.882 9.783 -47.016 1.00 74.92 ? 313 ALA A CA 1 ATOM 2389 C C . ALA A 1 313 ? -41.437 8.720 -46.083 1.00 76.15 ? 313 ALA A C 1 ATOM 2390 O O . ALA A 1 313 ? -41.730 9.022 -44.922 1.00 75.79 ? 313 ALA A O 1 ATOM 2391 C CB . ALA A 1 313 ? -39.410 10.047 -46.701 1.00 75.58 ? 313 ALA A CB 1 ATOM 2392 N N . GLU A 1 314 ? -41.628 7.497 -46.591 1.00 70.20 ? 314 GLU A N 1 ATOM 2393 C CA . GLU A 1 314 ? -42.139 6.399 -45.774 1.00 68.53 ? 314 GLU A CA 1 ATOM 2394 C C . GLU A 1 314 ? -40.978 5.553 -45.229 1.00 68.26 ? 314 GLU A C 1 ATOM 2395 O O . GLU A 1 314 ? -40.048 5.200 -45.965 1.00 68.66 ? 314 GLU A O 1 ATOM 2396 C CB . GLU A 1 314 ? -43.151 5.544 -46.560 1.00 69.89 ? 314 GLU A CB 1 ATOM 2397 C CG . GLU A 1 314 ? -43.913 4.537 -45.710 1.00 78.56 ? 314 GLU A CG 1 ATOM 2398 C CD . GLU A 1 314 ? -44.864 3.637 -46.472 1.00 97.70 ? 314 GLU A CD 1 ATOM 2399 O OE1 . GLU A 1 314 ? -44.408 2.984 -47.439 1.00 89.04 ? 314 GLU A OE1 1 ATOM 2400 O OE2 . GLU A 1 314 ? -46.053 3.553 -46.078 1.00 90.38 ? 314 GLU A OE2 1 ATOM 2401 N N . THR A 1 315 ? -41.032 5.248 -43.935 1.00 60.69 ? 315 THR A N 1 ATOM 2402 C CA . THR A 1 315 ? -40.019 4.416 -43.299 1.00 58.81 ? 315 THR A CA 1 ATOM 2403 C C . THR A 1 315 ? -40.347 2.948 -43.547 1.00 61.30 ? 315 THR A C 1 ATOM 2404 O O . THR A 1 315 ? -41.440 2.624 -44.023 1.00 60.36 ? 315 THR A O 1 ATOM 2405 C CB . THR A 1 315 ? -39.821 4.750 -41.807 1.00 55.25 ? 315 THR A CB 1 ATOM 2406 O OG1 . THR A 1 315 ? -40.857 4.153 -41.008 1.00 62.45 ? 315 THR A OG1 1 ATOM 2407 C CG2 . THR A 1 315 ? -39.671 6.226 -41.547 1.00 39.25 ? 315 THR A CG2 1 ATOM 2408 N N . GLN A 1 316 ? -39.414 2.066 -43.194 1.00 57.45 ? 316 GLN A N 1 ATOM 2409 C CA . GLN A 1 316 ? -39.583 0.645 -43.368 1.00 58.30 ? 316 GLN A CA 1 ATOM 2410 C C . GLN A 1 316 ? -40.756 0.060 -42.560 1.00 66.49 ? 316 GLN A C 1 ATOM 2411 O O . GLN A 1 316 ? -41.237 -1.024 -42.909 1.00 68.46 ? 316 GLN A O 1 ATOM 2412 C CB . GLN A 1 316 ? -38.259 -0.079 -43.089 1.00 59.66 ? 316 GLN A CB 1 ATOM 2413 C CG . GLN A 1 316 ? -37.318 -0.028 -44.319 1.00 69.38 ? 316 GLN A CG 1 ATOM 2414 C CD . GLN A 1 316 ? -35.930 -0.563 -44.077 1.00 67.98 ? 316 GLN A CD 1 ATOM 2415 O OE1 . GLN A 1 316 ? -35.742 -1.739 -43.810 1.00 57.34 ? 316 GLN A OE1 1 ATOM 2416 N NE2 . GLN A 1 316 ? -34.929 0.293 -44.185 1.00 59.90 ? 316 GLN A NE2 1 ATOM 2417 N N . HIS A 1 317 ? -41.277 0.800 -41.553 1.00 62.98 ? 317 HIS A N 1 ATOM 2418 C CA . HIS A 1 317 ? -42.377 0.298 -40.725 1.00 62.92 ? 317 HIS A CA 1 ATOM 2419 C C . HIS A 1 317 ? -43.712 0.934 -41.054 1.00 68.27 ? 317 HIS A C 1 ATOM 2420 O O . HIS A 1 317 ? -44.619 0.923 -40.216 1.00 71.13 ? 317 HIS A O 1 ATOM 2421 C CB . HIS A 1 317 ? -42.036 0.411 -39.229 1.00 63.54 ? 317 HIS A CB 1 ATOM 2422 C CG . HIS A 1 317 ? -40.642 -0.033 -38.949 1.00 67.10 ? 317 HIS A CG 1 ATOM 2423 N ND1 . HIS A 1 317 ? -40.314 -1.382 -38.910 1.00 68.51 ? 317 HIS A ND1 1 ATOM 2424 C CD2 . HIS A 1 317 ? -39.509 0.702 -38.833 1.00 68.53 ? 317 HIS A CD2 1 ATOM 2425 C CE1 . HIS A 1 317 ? -39.010 -1.422 -38.720 1.00 67.55 ? 317 HIS A CE1 1 ATOM 2426 N NE2 . HIS A 1 317 ? -38.480 -0.193 -38.665 1.00 67.95 ? 317 HIS A NE2 1 ATOM 2427 N N . GLY A 1 318 ? -43.849 1.442 -42.275 1.00 61.84 ? 318 GLY A N 1 ATOM 2428 C CA . GLY A 1 318 ? -45.087 2.080 -42.720 1.00 60.35 ? 318 GLY A CA 1 ATOM 2429 C C . GLY A 1 318 ? -45.294 3.523 -42.278 1.00 59.11 ? 318 GLY A C 1 ATOM 2430 O O . GLY A 1 318 ? -46.124 4.230 -42.861 1.00 58.70 ? 318 GLY A O 1 ATOM 2431 N N . THR A 1 319 ? -44.528 3.977 -41.267 1.00 51.83 ? 319 THR A N 1 ATOM 2432 C CA . THR A 1 319 ? -44.608 5.336 -40.737 1.00 50.58 ? 319 THR A CA 1 ATOM 2433 C C . THR A 1 319 ? -44.077 6.324 -41.754 1.00 50.78 ? 319 THR A C 1 ATOM 2434 O O . THR A 1 319 ? -43.337 5.948 -42.647 1.00 48.17 ? 319 THR A O 1 ATOM 2435 C CB . THR A 1 319 ? -43.895 5.483 -39.355 1.00 58.71 ? 319 THR A CB 1 ATOM 2436 O OG1 . THR A 1 319 ? -42.506 5.708 -39.561 1.00 60.14 ? 319 THR A OG1 1 ATOM 2437 C CG2 . THR A 1 319 ? -44.115 4.294 -38.408 1.00 52.59 ? 319 THR A CG2 1 ATOM 2438 N N . ILE A 1 320 ? -44.486 7.573 -41.640 1.00 49.22 ? 320 ILE A N 1 ATOM 2439 C CA . ILE A 1 320 ? -44.051 8.605 -42.562 1.00 51.30 ? 320 ILE A CA 1 ATOM 2440 C C . ILE A 1 320 ? -43.371 9.725 -41.839 1.00 60.56 ? 320 ILE A C 1 ATOM 2441 O O . ILE A 1 320 ? -43.636 9.949 -40.648 1.00 62.11 ? 320 ILE A O 1 ATOM 2442 C CB . ILE A 1 320 ? -45.191 9.114 -43.469 1.00 55.11 ? 320 ILE A CB 1 ATOM 2443 C CG1 . ILE A 1 320 ? -46.393 9.680 -42.668 1.00 55.84 ? 320 ILE A CG1 1 ATOM 2444 C CG2 . ILE A 1 320 ? -45.619 8.043 -44.436 1.00 56.83 ? 320 ILE A CG2 1 ATOM 2445 C CD1 . ILE A 1 320 ? -46.572 11.127 -42.838 1.00 64.06 ? 320 ILE A CD1 1 ATOM 2446 N N . VAL A 1 321 ? -42.491 10.437 -42.564 1.00 58.25 ? 321 VAL A N 1 ATOM 2447 C CA . VAL A 1 321 ? -41.726 11.568 -42.044 1.00 58.88 ? 321 VAL A CA 1 ATOM 2448 C C . VAL A 1 321 ? -41.892 12.793 -42.950 1.00 62.77 ? 321 VAL A C 1 ATOM 2449 O O . VAL A 1 321 ? -41.804 12.678 -44.167 1.00 62.86 ? 321 VAL A O 1 ATOM 2450 C CB . VAL A 1 321 ? -40.234 11.204 -41.765 1.00 62.59 ? 321 VAL A CB 1 ATOM 2451 C CG1 . VAL A 1 321 ? -39.489 12.347 -41.084 1.00 61.95 ? 321 VAL A CG1 1 ATOM 2452 C CG2 . VAL A 1 321 ? -40.142 9.953 -40.917 1.00 62.47 ? 321 VAL A CG2 1 ATOM 2453 N N . ILE A 1 322 ? -42.103 13.953 -42.341 1.00 59.52 ? 322 ILE A N 1 ATOM 2454 C CA . ILE A 1 322 ? -42.266 15.219 -43.028 1.00 60.58 ? 322 ILE A CA 1 ATOM 2455 C C . ILE A 1 322 ? -41.398 16.288 -42.397 1.00 67.99 ? 322 ILE A C 1 ATOM 2456 O O . ILE A 1 322 ? -41.388 16.412 -41.172 1.00 69.65 ? 322 ILE A O 1 ATOM 2457 C CB . ILE A 1 322 ? -43.787 15.607 -43.085 1.00 64.52 ? 322 ILE A CB 1 ATOM 2458 C CG1 . ILE A 1 322 ? -44.040 16.928 -43.820 1.00 66.51 ? 322 ILE A CG1 1 ATOM 2459 C CG2 . ILE A 1 322 ? -44.481 15.614 -41.730 1.00 65.13 ? 322 ILE A CG2 1 ATOM 2460 C CD1 . ILE A 1 322 ? -43.962 16.796 -45.383 1.00 83.75 ? 322 ILE A CD1 1 ATOM 2461 N N . ARG A 1 323 ? -40.631 17.041 -43.204 1.00 66.00 ? 323 ARG A N 1 ATOM 2462 C CA . ARG A 1 323 ? -39.859 18.179 -42.670 1.00 66.30 ? 323 ARG A CA 1 ATOM 2463 C C . ARG A 1 323 ? -40.494 19.515 -43.151 1.00 69.16 ? 323 ARG A C 1 ATOM 2464 O O . ARG A 1 323 ? -40.644 19.717 -44.355 1.00 69.03 ? 323 ARG A O 1 ATOM 2465 C CB . ARG A 1 323 ? -38.354 18.091 -42.948 1.00 67.68 ? 323 ARG A CB 1 ATOM 2466 C CG . ARG A 1 323 ? -37.533 19.026 -42.036 1.00 85.80 ? 323 ARG A CG 1 ATOM 2467 C CD . ARG A 1 323 ? -36.041 19.104 -42.375 1.00 96.43 ? 323 ARG A CD 1 ATOM 2468 N NE . ARG A 1 323 ? -35.358 17.814 -42.243 1.00 98.51 ? 323 ARG A NE 1 ATOM 2469 C CZ . ARG A 1 323 ? -34.321 17.431 -42.985 1.00 107.90 ? 323 ARG A CZ 1 ATOM 2470 N NH1 . ARG A 1 323 ? -33.830 18.236 -43.922 1.00 86.98 ? 323 ARG A NH1 1 ATOM 2471 N NH2 . ARG A 1 323 ? -33.771 16.235 -42.799 1.00 94.84 ? 323 ARG A NH2 1 ATOM 2472 N N . VAL A 1 324 ? -40.948 20.361 -42.211 1.00 64.13 ? 324 VAL A N 1 ATOM 2473 C CA . VAL A 1 324 ? -41.643 21.624 -42.483 1.00 63.80 ? 324 VAL A CA 1 ATOM 2474 C C . VAL A 1 324 ? -41.047 22.851 -41.780 1.00 70.99 ? 324 VAL A C 1 ATOM 2475 O O . VAL A 1 324 ? -40.592 22.748 -40.646 1.00 70.33 ? 324 VAL A O 1 ATOM 2476 C CB . VAL A 1 324 ? -43.159 21.538 -42.181 1.00 66.91 ? 324 VAL A CB 1 ATOM 2477 C CG1 . VAL A 1 324 ? -43.892 20.737 -43.247 1.00 67.08 ? 324 VAL A CG1 1 ATOM 2478 C CG2 . VAL A 1 324 ? -43.430 20.982 -40.790 1.00 66.42 ? 324 VAL A CG2 1 ATOM 2479 N N . GLN A 1 325 ? -41.138 24.029 -42.425 1.00 69.87 ? 325 GLN A N 1 ATOM 2480 C CA . GLN A 1 325 ? -40.687 25.306 -41.864 1.00 70.27 ? 325 GLN A CA 1 ATOM 2481 C C . GLN A 1 325 ? -41.887 26.243 -41.613 1.00 72.17 ? 325 GLN A C 1 ATOM 2482 O O . GLN A 1 325 ? -42.751 26.374 -42.481 1.00 71.59 ? 325 GLN A O 1 ATOM 2483 C CB . GLN A 1 325 ? -39.682 25.974 -42.806 1.00 72.52 ? 325 GLN A CB 1 ATOM 2484 C CG . GLN A 1 325 ? -38.436 26.493 -42.095 1.00 94.10 ? 325 GLN A CG 1 ATOM 2485 C CD . GLN A 1 325 ? -37.625 27.456 -42.933 1.00 114.22 ? 325 GLN A CD 1 ATOM 2486 O OE1 . GLN A 1 325 ? -37.753 27.531 -44.167 1.00 111.70 ? 325 GLN A OE1 1 ATOM 2487 N NE2 . GLN A 1 325 ? -36.755 28.210 -42.277 1.00 105.79 ? 325 GLN A NE2 1 ATOM 2488 N N . TYR A 1 326 ? -41.954 26.868 -40.417 1.00 67.84 ? 326 TYR A N 1 ATOM 2489 C CA . TYR A 1 326 ? -43.046 27.792 -40.038 1.00 66.86 ? 326 TYR A CA 1 ATOM 2490 C C . TYR A 1 326 ? -42.763 29.172 -40.567 1.00 70.90 ? 326 TYR A C 1 ATOM 2491 O O . TYR A 1 326 ? -41.643 29.668 -40.420 1.00 72.90 ? 326 TYR A O 1 ATOM 2492 C CB . TYR A 1 326 ? -43.251 27.834 -38.504 1.00 66.46 ? 326 TYR A CB 1 ATOM 2493 C CG . TYR A 1 326 ? -44.367 28.726 -37.982 1.00 64.86 ? 326 TYR A CG 1 ATOM 2494 C CD1 . TYR A 1 326 ? -45.672 28.598 -38.456 1.00 64.97 ? 326 TYR A CD1 1 ATOM 2495 C CD2 . TYR A 1 326 ? -44.145 29.604 -36.923 1.00 65.37 ? 326 TYR A CD2 1 ATOM 2496 C CE1 . TYR A 1 326 ? -46.718 29.352 -37.918 1.00 62.88 ? 326 TYR A CE1 1 ATOM 2497 C CE2 . TYR A 1 326 ? -45.184 30.362 -36.375 1.00 65.89 ? 326 TYR A CE2 1 ATOM 2498 C CZ . TYR A 1 326 ? -46.469 30.234 -36.877 1.00 69.07 ? 326 TYR A CZ 1 ATOM 2499 O OH . TYR A 1 326 ? -47.476 31.008 -36.351 1.00 67.12 ? 326 TYR A OH 1 ATOM 2500 N N . GLU A 1 327 ? -43.771 29.790 -41.183 1.00 64.92 ? 327 GLU A N 1 ATOM 2501 C CA . GLU A 1 327 ? -43.632 31.112 -41.773 1.00 64.49 ? 327 GLU A CA 1 ATOM 2502 C C . GLU A 1 327 ? -44.459 32.188 -41.058 1.00 69.81 ? 327 GLU A C 1 ATOM 2503 O O . GLU A 1 327 ? -44.538 33.308 -41.547 1.00 70.06 ? 327 GLU A O 1 ATOM 2504 C CB . GLU A 1 327 ? -43.928 31.041 -43.273 1.00 65.55 ? 327 GLU A CB 1 ATOM 2505 C CG . GLU A 1 327 ? -42.874 30.242 -44.018 1.00 75.37 ? 327 GLU A CG 1 ATOM 2506 C CD . GLU A 1 327 ? -43.204 29.923 -45.461 1.00 113.47 ? 327 GLU A CD 1 ATOM 2507 O OE1 . GLU A 1 327 ? -44.208 29.214 -45.701 1.00 118.11 ? 327 GLU A OE1 1 ATOM 2508 O OE2 . GLU A 1 327 ? -42.466 30.395 -46.356 1.00 117.25 ? 327 GLU A OE2 1 ATOM 2509 N N . GLY A 1 328 ? -45.003 31.846 -39.889 1.00 67.97 ? 328 GLY A N 1 ATOM 2510 C CA . GLY A 1 328 ? -45.824 32.721 -39.055 1.00 69.03 ? 328 GLY A CA 1 ATOM 2511 C C . GLY A 1 328 ? -45.014 33.498 -38.036 1.00 76.20 ? 328 GLY A C 1 ATOM 2512 O O . GLY A 1 328 ? -43.820 33.718 -38.260 1.00 75.55 ? 328 GLY A O 1 ATOM 2513 N N . ASP A 1 329 ? -45.650 33.941 -36.916 1.00 75.25 ? 329 ASP A N 1 ATOM 2514 C CA . ASP A 1 329 ? -44.956 34.753 -35.899 1.00 76.11 ? 329 ASP A CA 1 ATOM 2515 C C . ASP A 1 329 ? -45.091 34.290 -34.425 1.00 80.91 ? 329 ASP A C 1 ATOM 2516 O O . ASP A 1 329 ? -44.242 34.665 -33.598 1.00 82.03 ? 329 ASP A O 1 ATOM 2517 C CB . ASP A 1 329 ? -45.370 36.236 -35.996 1.00 78.16 ? 329 ASP A CB 1 ATOM 2518 C CG . ASP A 1 329 ? -45.095 36.908 -37.333 1.00 93.40 ? 329 ASP A CG 1 ATOM 2519 O OD1 . ASP A 1 329 ? -43.945 36.798 -37.842 1.00 92.30 ? 329 ASP A OD1 1 ATOM 2520 O OD2 . ASP A 1 329 ? -45.992 37.604 -37.831 1.00 103.81 ? 329 ASP A OD2 1 ATOM 2521 N N . GLY A 1 330 ? -46.131 33.508 -34.116 1.00 74.58 ? 330 GLY A N 1 ATOM 2522 C CA . GLY A 1 330 ? -46.434 33.055 -32.761 1.00 73.12 ? 330 GLY A CA 1 ATOM 2523 C C . GLY A 1 330 ? -45.389 32.301 -31.957 1.00 74.89 ? 330 GLY A C 1 ATOM 2524 O O . GLY A 1 330 ? -45.517 32.220 -30.730 1.00 72.74 ? 330 GLY A O 1 ATOM 2525 N N . SER A 1 331 ? -44.347 31.756 -32.632 1.00 72.75 ? 331 SER A N 1 ATOM 2526 C CA . SER A 1 331 ? -43.279 30.896 -32.087 1.00 72.63 ? 331 SER A CA 1 ATOM 2527 C C . SER A 1 331 ? -42.672 31.398 -30.776 1.00 77.59 ? 331 SER A C 1 ATOM 2528 O O . SER A 1 331 ? -42.403 32.593 -30.642 1.00 77.39 ? 331 SER A O 1 ATOM 2529 C CB . SER A 1 331 ? -42.194 30.616 -33.122 1.00 76.37 ? 331 SER A CB 1 ATOM 2530 O OG . SER A 1 331 ? -41.249 31.666 -33.233 1.00 91.12 ? 331 SER A OG 1 ATOM 2531 N N . PRO A 1 332 ? -42.502 30.518 -29.764 1.00 75.10 ? 332 PRO A N 1 ATOM 2532 C CA . PRO A 1 332 ? -42.762 29.060 -29.746 1.00 74.32 ? 332 PRO A CA 1 ATOM 2533 C C . PRO A 1 332 ? -44.246 28.699 -29.719 1.00 76.31 ? 332 PRO A C 1 ATOM 2534 O O . PRO A 1 332 ? -45.017 29.248 -28.910 1.00 77.85 ? 332 PRO A O 1 ATOM 2535 C CB . PRO A 1 332 ? -41.986 28.587 -28.517 1.00 76.06 ? 332 PRO A CB 1 ATOM 2536 C CG . PRO A 1 332 ? -42.023 29.778 -27.588 1.00 80.90 ? 332 PRO A CG 1 ATOM 2537 C CD . PRO A 1 332 ? -41.958 30.988 -28.473 1.00 76.73 ? 332 PRO A CD 1 ATOM 2538 N N . CYS A 1 333 ? -44.658 27.817 -30.647 1.00 68.79 ? 333 CYS A N 1 ATOM 2539 C CA . CYS A 1 333 ? -46.055 27.399 -30.761 1.00 67.09 ? 333 CYS A CA 1 ATOM 2540 C C . CYS A 1 333 ? -46.211 25.918 -31.191 1.00 64.89 ? 333 CYS A C 1 ATOM 2541 O O . CYS A 1 333 ? -45.305 25.358 -31.824 1.00 63.43 ? 333 CYS A O 1 ATOM 2542 C CB . CYS A 1 333 ? -46.836 28.354 -31.671 1.00 67.73 ? 333 CYS A CB 1 ATOM 2543 S SG . CYS A 1 333 ? -46.192 28.478 -33.365 1.00 72.21 ? 333 CYS A SG 1 ATOM 2544 N N . LYS A 1 334 ? -47.373 25.304 -30.854 1.00 57.33 ? 334 LYS A N 1 ATOM 2545 C CA . LYS A 1 334 ? -47.709 23.930 -31.246 1.00 55.92 ? 334 LYS A CA 1 ATOM 2546 C C . LYS A 1 334 ? -48.097 23.909 -32.755 1.00 58.47 ? 334 LYS A C 1 ATOM 2547 O O . LYS A 1 334 ? -49.025 24.640 -33.162 1.00 58.72 ? 334 LYS A O 1 ATOM 2548 C CB . LYS A 1 334 ? -48.922 23.401 -30.437 1.00 56.83 ? 334 LYS A CB 1 ATOM 2549 C CG . LYS A 1 334 ? -48.751 23.136 -28.959 1.00 47.86 ? 334 LYS A CG 1 ATOM 2550 C CD . LYS A 1 334 ? -50.069 22.547 -28.416 1.00 56.67 ? 334 LYS A CD 1 ATOM 2551 C CE . LYS A 1 334 ? -50.137 22.421 -26.900 1.00 75.31 ? 334 LYS A CE 1 ATOM 2552 N NZ . LYS A 1 334 ? -51.261 21.562 -26.423 1.00 72.39 ? 334 LYS A NZ 1 ATOM 2553 N N . ILE A 1 335 ? -47.423 23.062 -33.572 1.00 51.15 ? 335 ILE A N 1 ATOM 2554 C CA . ILE A 1 335 ? -47.760 22.920 -34.996 1.00 49.26 ? 335 ILE A CA 1 ATOM 2555 C C . ILE A 1 335 ? -49.038 22.099 -35.043 1.00 57.77 ? 335 ILE A C 1 ATOM 2556 O O . ILE A 1 335 ? -49.056 21.004 -34.456 1.00 58.47 ? 335 ILE A O 1 ATOM 2557 C CB . ILE A 1 335 ? -46.700 22.174 -35.813 1.00 50.84 ? 335 ILE A CB 1 ATOM 2558 C CG1 . ILE A 1 335 ? -45.290 22.676 -35.587 1.00 52.57 ? 335 ILE A CG1 1 ATOM 2559 C CG2 . ILE A 1 335 ? -47.047 22.191 -37.255 1.00 49.01 ? 335 ILE A CG2 1 ATOM 2560 C CD1 . ILE A 1 335 ? -44.205 21.578 -35.609 1.00 60.05 ? 335 ILE A CD1 1 ATOM 2561 N N . PRO A 1 336 ? -50.121 22.578 -35.718 1.00 56.20 ? 336 PRO A N 1 ATOM 2562 C CA . PRO A 1 336 ? -51.352 21.770 -35.792 1.00 55.27 ? 336 PRO A CA 1 ATOM 2563 C C . PRO A 1 336 ? -51.123 20.604 -36.751 1.00 55.74 ? 336 PRO A C 1 ATOM 2564 O O . PRO A 1 336 ? -50.565 20.785 -37.837 1.00 55.37 ? 336 PRO A O 1 ATOM 2565 C CB . PRO A 1 336 ? -52.415 22.765 -36.299 1.00 56.66 ? 336 PRO A CB 1 ATOM 2566 C CG . PRO A 1 336 ? -51.762 24.111 -36.267 1.00 61.13 ? 336 PRO A CG 1 ATOM 2567 C CD . PRO A 1 336 ? -50.298 23.851 -36.438 1.00 57.70 ? 336 PRO A CD 1 ATOM 2568 N N . PHE A 1 337 ? -51.488 19.403 -36.323 1.00 49.05 ? 337 PHE A N 1 ATOM 2569 C CA . PHE A 1 337 ? -51.289 18.228 -37.150 1.00 47.62 ? 337 PHE A CA 1 ATOM 2570 C C . PHE A 1 337 ? -52.453 17.286 -37.066 1.00 50.39 ? 337 PHE A C 1 ATOM 2571 O O . PHE A 1 337 ? -52.976 17.029 -35.972 1.00 46.91 ? 337 PHE A O 1 ATOM 2572 C CB . PHE A 1 337 ? -49.991 17.521 -36.759 1.00 48.93 ? 337 PHE A CB 1 ATOM 2573 C CG . PHE A 1 337 ? -49.488 16.515 -37.748 1.00 49.30 ? 337 PHE A CG 1 ATOM 2574 C CD1 . PHE A 1 337 ? -48.681 16.908 -38.805 1.00 51.56 ? 337 PHE A CD1 1 ATOM 2575 C CD2 . PHE A 1 337 ? -49.774 15.168 -37.591 1.00 51.78 ? 337 PHE A CD2 1 ATOM 2576 C CE1 . PHE A 1 337 ? -48.191 15.973 -39.706 1.00 54.70 ? 337 PHE A CE1 1 ATOM 2577 C CE2 . PHE A 1 337 ? -49.286 14.230 -38.486 1.00 53.23 ? 337 PHE A CE2 1 ATOM 2578 C CZ . PHE A 1 337 ? -48.482 14.638 -39.531 1.00 53.06 ? 337 PHE A CZ 1 ATOM 2579 N N . GLU A 1 338 ? -52.852 16.755 -38.236 1.00 49.59 ? 338 GLU A N 1 ATOM 2580 C CA . GLU A 1 338 ? -53.962 15.826 -38.345 1.00 50.34 ? 338 GLU A CA 1 ATOM 2581 C C . GLU A 1 338 ? -53.846 14.896 -39.526 1.00 55.25 ? 338 GLU A C 1 ATOM 2582 O O . GLU A 1 338 ? -53.328 15.274 -40.578 1.00 52.30 ? 338 GLU A O 1 ATOM 2583 C CB . GLU A 1 338 ? -55.309 16.562 -38.377 1.00 52.09 ? 338 GLU A CB 1 ATOM 2584 C CG . GLU A 1 338 ? -56.372 15.814 -37.593 1.00 72.90 ? 338 GLU A CG 1 ATOM 2585 C CD . GLU A 1 338 ? -57.293 16.665 -36.735 1.00 117.12 ? 338 GLU A CD 1 ATOM 2586 O OE1 . GLU A 1 338 ? -56.972 16.867 -35.539 1.00 121.25 ? 338 GLU A OE1 1 ATOM 2587 O OE2 . GLU A 1 338 ? -58.373 17.062 -37.235 1.00 115.97 ? 338 GLU A OE2 1 ATOM 2588 N N . ILE A 1 339 ? -54.360 13.668 -39.337 1.00 54.25 ? 339 ILE A N 1 ATOM 2589 C CA . ILE A 1 339 ? -54.440 12.632 -40.366 1.00 53.86 ? 339 ILE A CA 1 ATOM 2590 C C . ILE A 1 339 ? -55.917 12.287 -40.379 1.00 59.59 ? 339 ILE A C 1 ATOM 2591 O O . ILE A 1 339 ? -56.474 11.890 -39.343 1.00 59.25 ? 339 ILE A O 1 ATOM 2592 C CB . ILE A 1 339 ? -53.500 11.408 -40.077 1.00 56.19 ? 339 ILE A CB 1 ATOM 2593 C CG1 . ILE A 1 339 ? -52.033 11.753 -40.353 1.00 55.66 ? 339 ILE A CG1 1 ATOM 2594 C CG2 . ILE A 1 339 ? -53.886 10.207 -40.910 1.00 57.17 ? 339 ILE A CG2 1 ATOM 2595 C CD1 . ILE A 1 339 ? -51.109 11.171 -39.430 1.00 59.63 ? 339 ILE A CD1 1 ATOM 2596 N N . THR A 1 340 ? -56.580 12.542 -41.509 1.00 57.18 ? 340 THR A N 1 ATOM 2597 C CA . THR A 1 340 ? -58.015 12.240 -41.605 1.00 57.07 ? 340 THR A CA 1 ATOM 2598 C C . THR A 1 340 ? -58.303 11.446 -42.833 1.00 61.34 ? 340 THR A C 1 ATOM 2599 O O . THR A 1 340 ? -57.457 11.372 -43.724 1.00 61.19 ? 340 THR A O 1 ATOM 2600 C CB . THR A 1 340 ? -58.879 13.493 -41.693 1.00 55.84 ? 340 THR A CB 1 ATOM 2601 O OG1 . THR A 1 340 ? -58.417 14.268 -42.789 1.00 44.23 ? 340 THR A OG1 1 ATOM 2602 C CG2 . THR A 1 340 ? -58.955 14.268 -40.385 1.00 53.79 ? 340 THR A CG2 1 ATOM 2603 N N . ASP A 1 341 ? -59.541 10.923 -42.912 1.00 57.61 ? 341 ASP A N 1 ATOM 2604 C CA . ASP A 1 341 ? -60.066 10.210 -44.072 1.00 57.25 ? 341 ASP A CA 1 ATOM 2605 C C . ASP A 1 341 ? -60.124 11.222 -45.225 1.00 58.94 ? 341 ASP A C 1 ATOM 2606 O O . ASP A 1 341 ? -59.924 12.419 -44.982 1.00 56.95 ? 341 ASP A O 1 ATOM 2607 C CB . ASP A 1 341 ? -61.470 9.619 -43.755 1.00 58.98 ? 341 ASP A CB 1 ATOM 2608 C CG . ASP A 1 341 ? -62.605 10.617 -43.527 1.00 67.40 ? 341 ASP A CG 1 ATOM 2609 O OD1 . ASP A 1 341 ? -62.346 11.686 -42.949 1.00 72.29 ? 341 ASP A OD1 1 ATOM 2610 O OD2 . ASP A 1 341 ? -63.756 10.313 -43.921 1.00 68.19 ? 341 ASP A OD2 1 ATOM 2611 N N . LEU A 1 342 ? -60.381 10.759 -46.460 1.00 55.26 ? 342 LEU A N 1 ATOM 2612 C CA . LEU A 1 342 ? -60.458 11.677 -47.606 1.00 55.01 ? 342 LEU A CA 1 ATOM 2613 C C . LEU A 1 342 ? -61.504 12.762 -47.471 1.00 56.97 ? 342 LEU A C 1 ATOM 2614 O O . LEU A 1 342 ? -61.246 13.877 -47.909 1.00 54.98 ? 342 LEU A O 1 ATOM 2615 C CB . LEU A 1 342 ? -60.648 10.943 -48.940 1.00 55.10 ? 342 LEU A CB 1 ATOM 2616 C CG . LEU A 1 342 ? -59.497 10.075 -49.421 1.00 59.08 ? 342 LEU A CG 1 ATOM 2617 C CD1 . LEU A 1 342 ? -59.702 9.680 -50.867 1.00 58.80 ? 342 LEU A CD1 1 ATOM 2618 C CD2 . LEU A 1 342 ? -58.150 10.757 -49.202 1.00 60.26 ? 342 LEU A CD2 1 ATOM 2619 N N . GLU A 1 343 ? -62.653 12.443 -46.823 1.00 54.77 ? 343 GLU A N 1 ATOM 2620 C CA . GLU A 1 343 ? -63.783 13.350 -46.606 1.00 55.09 ? 343 GLU A CA 1 ATOM 2621 C C . GLU A 1 343 ? -63.596 14.305 -45.426 1.00 57.07 ? 343 GLU A C 1 ATOM 2622 O O . GLU A 1 343 ? -64.523 15.048 -45.125 1.00 56.60 ? 343 GLU A O 1 ATOM 2623 C CB . GLU A 1 343 ? -65.112 12.576 -46.499 1.00 57.30 ? 343 GLU A CB 1 ATOM 2624 C CG . GLU A 1 343 ? -65.990 12.704 -47.752 1.00 74.01 ? 343 GLU A CG 1 ATOM 2625 C CD . GLU A 1 343 ? -67.440 13.100 -47.502 1.00 115.32 ? 343 GLU A CD 1 ATOM 2626 O OE1 . GLU A 1 343 ? -67.709 14.307 -47.285 1.00 110.65 ? 343 GLU A OE1 1 ATOM 2627 O OE2 . GLU A 1 343 ? -68.310 12.197 -47.499 1.00 124.80 ? 343 GLU A OE2 1 ATOM 2628 N N . LYS A 1 344 ? -62.374 14.341 -44.827 1.00 53.24 ? 344 LYS A N 1 ATOM 2629 C CA . LYS A 1 344 ? -61.902 15.186 -43.714 1.00 52.20 ? 344 LYS A CA 1 ATOM 2630 C C . LYS A 1 344 ? -62.947 15.271 -42.580 1.00 56.85 ? 344 LYS A C 1 ATOM 2631 O O . LYS A 1 344 ? -63.406 16.361 -42.224 1.00 57.90 ? 344 LYS A O 1 ATOM 2632 C CB . LYS A 1 344 ? -61.455 16.557 -44.263 1.00 54.09 ? 344 LYS A CB 1 ATOM 2633 C CG . LYS A 1 344 ? -60.612 17.401 -43.286 1.00 77.81 ? 344 LYS A CG 1 ATOM 2634 C CD . LYS A 1 344 ? -60.236 18.800 -43.851 1.00 88.98 ? 344 LYS A CD 1 ATOM 2635 C CE . LYS A 1 344 ? -60.333 19.929 -42.831 1.00 89.75 ? 344 LYS A CE 1 ATOM 2636 N NZ . LYS A 1 344 ? -59.792 21.224 -43.359 1.00 87.41 ? 344 LYS A NZ 1 ATOM 2637 N N . ARG A 1 345 ? -63.366 14.084 -42.069 1.00 52.54 ? 345 ARG A N 1 ATOM 2638 C CA . ARG A 1 345 ? -64.431 13.844 -41.067 1.00 51.71 ? 345 ARG A CA 1 ATOM 2639 C C . ARG A 1 345 ? -63.949 12.956 -39.909 1.00 56.01 ? 345 ARG A C 1 ATOM 2640 O O . ARG A 1 345 ? -64.283 13.215 -38.742 1.00 56.03 ? 345 ARG A O 1 ATOM 2641 C CB . ARG A 1 345 ? -65.659 13.200 -41.765 1.00 50.67 ? 345 ARG A CB 1 ATOM 2642 C CG . ARG A 1 345 ? -66.702 12.561 -40.840 1.00 59.57 ? 345 ARG A CG 1 ATOM 2643 C CD . ARG A 1 345 ? -67.825 11.846 -41.563 1.00 71.76 ? 345 ARG A CD 1 ATOM 2644 N NE . ARG A 1 345 ? -68.641 12.737 -42.391 1.00 87.48 ? 345 ARG A NE 1 ATOM 2645 C CZ . ARG A 1 345 ? -68.930 12.511 -43.670 1.00 107.85 ? 345 ARG A CZ 1 ATOM 2646 N NH1 . ARG A 1 345 ? -68.466 11.425 -44.283 1.00 95.56 ? 345 ARG A NH1 1 ATOM 2647 N NH2 . ARG A 1 345 ? -69.683 13.371 -44.349 1.00 96.30 ? 345 ARG A NH2 1 ATOM 2648 N N . HIS A 1 346 ? -63.170 11.911 -40.245 1.00 52.29 ? 346 HIS A N 1 ATOM 2649 C CA . HIS A 1 346 ? -62.613 10.967 -39.288 1.00 51.71 ? 346 HIS A CA 1 ATOM 2650 C C . HIS A 1 346 ? -61.162 11.179 -38.979 1.00 57.63 ? 346 HIS A C 1 ATOM 2651 O O . HIS A 1 346 ? -60.330 11.237 -39.886 1.00 57.14 ? 346 HIS A O 1 ATOM 2652 C CB . HIS A 1 346 ? -62.827 9.540 -39.764 1.00 51.74 ? 346 HIS A CB 1 ATOM 2653 C CG . HIS A 1 346 ? -64.244 9.131 -39.606 1.00 54.72 ? 346 HIS A CG 1 ATOM 2654 N ND1 . HIS A 1 346 ? -65.195 9.432 -40.568 1.00 56.34 ? 346 HIS A ND1 1 ATOM 2655 C CD2 . HIS A 1 346 ? -64.855 8.584 -38.543 1.00 55.49 ? 346 HIS A CD2 1 ATOM 2656 C CE1 . HIS A 1 346 ? -66.333 8.973 -40.092 1.00 55.24 ? 346 HIS A CE1 1 ATOM 2657 N NE2 . HIS A 1 346 ? -66.181 8.475 -38.872 1.00 55.48 ? 346 HIS A NE2 1 ATOM 2658 N N . VAL A 1 347 ? -60.844 11.260 -37.675 1.00 55.11 ? 347 VAL A N 1 ATOM 2659 C CA . VAL A 1 347 ? -59.449 11.359 -37.245 1.00 53.90 ? 347 VAL A CA 1 ATOM 2660 C C . VAL A 1 347 ? -58.894 9.943 -37.267 1.00 56.83 ? 347 VAL A C 1 ATOM 2661 O O . VAL A 1 347 ? -59.508 9.014 -36.714 1.00 56.28 ? 347 VAL A O 1 ATOM 2662 C CB . VAL A 1 347 ? -59.187 12.103 -35.921 1.00 56.11 ? 347 VAL A CB 1 ATOM 2663 C CG1 . VAL A 1 347 ? -57.690 12.146 -35.633 1.00 56.15 ? 347 VAL A CG1 1 ATOM 2664 C CG2 . VAL A 1 347 ? -59.727 13.516 -35.998 1.00 55.52 ? 347 VAL A CG2 1 ATOM 2665 N N . LEU A 1 348 ? -57.778 9.789 -37.990 1.00 51.14 ? 348 LEU A N 1 ATOM 2666 C CA . LEU A 1 348 ? -57.144 8.516 -38.218 1.00 50.31 ? 348 LEU A CA 1 ATOM 2667 C C . LEU A 1 348 ? -55.661 8.529 -37.895 1.00 57.26 ? 348 LEU A C 1 ATOM 2668 O O . LEU A 1 348 ? -55.052 9.606 -37.824 1.00 56.54 ? 348 LEU A O 1 ATOM 2669 C CB . LEU A 1 348 ? -57.364 8.130 -39.688 1.00 49.48 ? 348 LEU A CB 1 ATOM 2670 C CG . LEU A 1 348 ? -58.789 7.813 -40.158 1.00 50.89 ? 348 LEU A CG 1 ATOM 2671 C CD1 . LEU A 1 348 ? -58.869 7.902 -41.662 1.00 49.44 ? 348 LEU A CD1 1 ATOM 2672 C CD2 . LEU A 1 348 ? -59.239 6.441 -39.680 1.00 49.90 ? 348 LEU A CD2 1 ATOM 2673 N N . GLY A 1 349 ? -55.106 7.323 -37.696 1.00 56.92 ? 349 GLY A N 1 ATOM 2674 C CA . GLY A 1 349 ? -53.703 7.089 -37.378 1.00 58.52 ? 349 GLY A CA 1 ATOM 2675 C C . GLY A 1 349 ? -53.224 7.838 -36.142 1.00 67.53 ? 349 GLY A C 1 ATOM 2676 O O . GLY A 1 349 ? -54.000 8.540 -35.487 1.00 70.17 ? 349 GLY A O 1 ATOM 2677 N N . ARG A 1 350 ? -51.932 7.738 -35.825 1.00 62.52 ? 350 ARG A N 1 ATOM 2678 C CA . ARG A 1 350 ? -51.375 8.373 -34.631 1.00 60.13 ? 350 ARG A CA 1 ATOM 2679 C C . ARG A 1 350 ? -50.102 9.177 -34.915 1.00 58.81 ? 350 ARG A C 1 ATOM 2680 O O . ARG A 1 350 ? -49.525 9.051 -35.995 1.00 59.16 ? 350 ARG A O 1 ATOM 2681 C CB . ARG A 1 350 ? -51.168 7.324 -33.511 1.00 59.42 ? 350 ARG A CB 1 ATOM 2682 C CG . ARG A 1 350 ? -50.100 6.270 -33.752 1.00 65.61 ? 350 ARG A CG 1 ATOM 2683 C CD . ARG A 1 350 ? -49.759 5.578 -32.437 1.00 88.54 ? 350 ARG A CD 1 ATOM 2684 N NE . ARG A 1 350 ? -48.738 4.538 -32.608 1.00 113.00 ? 350 ARG A NE 1 ATOM 2685 C CZ . ARG A 1 350 ? -48.988 3.231 -32.693 1.00 131.08 ? 350 ARG A CZ 1 ATOM 2686 N NH1 . ARG A 1 350 ? -50.231 2.778 -32.597 1.00 119.24 ? 350 ARG A NH1 1 ATOM 2687 N NH2 . ARG A 1 350 ? -47.995 2.369 -32.860 1.00 115.88 ? 350 ARG A NH2 1 ATOM 2688 N N . LEU A 1 351 ? -49.670 9.998 -33.953 1.00 50.83 ? 351 LEU A N 1 ATOM 2689 C CA . LEU A 1 351 ? -48.483 10.826 -34.070 1.00 48.87 ? 351 LEU A CA 1 ATOM 2690 C C . LEU A 1 351 ? -47.299 10.238 -33.252 1.00 53.60 ? 351 LEU A C 1 ATOM 2691 O O . LEU A 1 351 ? -47.392 10.137 -32.032 1.00 55.19 ? 351 LEU A O 1 ATOM 2692 C CB . LEU A 1 351 ? -48.823 12.218 -33.541 1.00 48.04 ? 351 LEU A CB 1 ATOM 2693 C CG . LEU A 1 351 ? -48.639 13.377 -34.472 1.00 52.86 ? 351 LEU A CG 1 ATOM 2694 C CD1 . LEU A 1 351 ? -48.750 14.646 -33.725 1.00 53.08 ? 351 LEU A CD1 1 ATOM 2695 C CD2 . LEU A 1 351 ? -47.264 13.381 -35.134 1.00 57.03 ? 351 LEU A CD2 1 ATOM 2696 N N . ILE A 1 352 ? -46.183 9.882 -33.900 1.00 47.27 ? 352 ILE A N 1 ATOM 2697 C CA . ILE A 1 352 ? -45.029 9.374 -33.166 1.00 45.72 ? 352 ILE A CA 1 ATOM 2698 C C . ILE A 1 352 ? -44.350 10.570 -32.487 1.00 52.18 ? 352 ILE A C 1 ATOM 2699 O O . ILE A 1 352 ? -44.264 10.569 -31.259 1.00 53.43 ? 352 ILE A O 1 ATOM 2700 C CB . ILE A 1 352 ? -44.072 8.522 -34.026 1.00 47.03 ? 352 ILE A CB 1 ATOM 2701 C CG1 . ILE A 1 352 ? -44.829 7.418 -34.844 1.00 45.38 ? 352 ILE A CG1 1 ATOM 2702 C CG2 . ILE A 1 352 ? -42.923 7.950 -33.170 1.00 46.68 ? 352 ILE A CG2 1 ATOM 2703 C CD1 . ILE A 1 352 ? -45.477 6.288 -34.104 1.00 35.54 ? 352 ILE A CD1 1 ATOM 2704 N N . THR A 1 353 ? -43.952 11.619 -33.268 1.00 47.04 ? 353 THR A N 1 ATOM 2705 C CA . THR A 1 353 ? -43.363 12.864 -32.748 1.00 45.55 ? 353 THR A CA 1 ATOM 2706 C C . THR A 1 353 ? -44.510 13.684 -32.101 1.00 49.11 ? 353 THR A C 1 ATOM 2707 O O . THR A 1 353 ? -44.955 14.691 -32.666 1.00 48.59 ? 353 THR A O 1 ATOM 2708 C CB . THR A 1 353 ? -42.647 13.650 -33.874 1.00 50.43 ? 353 THR A CB 1 ATOM 2709 O OG1 . THR A 1 353 ? -41.946 12.752 -34.748 1.00 53.80 ? 353 THR A OG1 1 ATOM 2710 C CG2 . THR A 1 353 ? -41.711 14.742 -33.340 1.00 45.14 ? 353 THR A CG2 1 ATOM 2711 N N . VAL A 1 354 ? -44.986 13.229 -30.913 1.00 45.52 ? 354 VAL A N 1 ATOM 2712 C CA . VAL A 1 354 ? -46.080 13.853 -30.150 1.00 44.71 ? 354 VAL A CA 1 ATOM 2713 C C . VAL A 1 354 ? -45.782 15.312 -29.815 1.00 48.45 ? 354 VAL A C 1 ATOM 2714 O O . VAL A 1 354 ? -44.608 15.654 -29.538 1.00 45.93 ? 354 VAL A O 1 ATOM 2715 C CB . VAL A 1 354 ? -46.559 13.080 -28.884 1.00 46.72 ? 354 VAL A CB 1 ATOM 2716 C CG1 . VAL A 1 354 ? -46.932 11.645 -29.211 1.00 45.81 ? 354 VAL A CG1 1 ATOM 2717 C CG2 . VAL A 1 354 ? -45.536 13.143 -27.755 1.00 46.75 ? 354 VAL A CG2 1 ATOM 2718 N N . ASN A 1 355 ? -46.881 16.147 -29.824 1.00 44.48 ? 355 ASN A N 1 ATOM 2719 C CA . ASN A 1 355 ? -46.919 17.582 -29.531 1.00 44.16 ? 355 ASN A CA 1 ATOM 2720 C C . ASN A 1 355 ? -45.870 18.338 -30.352 1.00 53.94 ? 355 ASN A C 1 ATOM 2721 O O . ASN A 1 355 ? -44.967 18.946 -29.754 1.00 54.79 ? 355 ASN A O 1 ATOM 2722 C CB . ASN A 1 355 ? -46.757 17.843 -28.026 1.00 39.16 ? 355 ASN A CB 1 ATOM 2723 C CG . ASN A 1 355 ? -47.257 19.202 -27.618 1.00 64.97 ? 355 ASN A CG 1 ATOM 2724 O OD1 . ASN A 1 355 ? -48.466 19.466 -27.609 1.00 59.30 ? 355 ASN A OD1 1 ATOM 2725 N ND2 . ASN A 1 355 ? -46.339 20.104 -27.284 1.00 57.89 ? 355 ASN A ND2 1 ATOM 2726 N N . PRO A 1 356 ? -45.915 18.266 -31.718 1.00 53.38 ? 356 PRO A N 1 ATOM 2727 C CA . PRO A 1 356 ? -44.866 18.937 -32.523 1.00 54.47 ? 356 PRO A CA 1 ATOM 2728 C C . PRO A 1 356 ? -44.883 20.431 -32.308 1.00 62.57 ? 356 PRO A C 1 ATOM 2729 O O . PRO A 1 356 ? -45.969 21.035 -32.333 1.00 64.21 ? 356 PRO A O 1 ATOM 2730 C CB . PRO A 1 356 ? -45.194 18.537 -33.963 1.00 55.96 ? 356 PRO A CB 1 ATOM 2731 C CG . PRO A 1 356 ? -46.627 18.162 -33.939 1.00 59.56 ? 356 PRO A CG 1 ATOM 2732 C CD . PRO A 1 356 ? -46.896 17.580 -32.582 1.00 54.81 ? 356 PRO A CD 1 ATOM 2733 N N . ILE A 1 357 ? -43.714 21.009 -31.991 1.00 59.47 ? 357 ILE A N 1 ATOM 2734 C CA . ILE A 1 357 ? -43.642 22.441 -31.694 1.00 59.61 ? 357 ILE A CA 1 ATOM 2735 C C . ILE A 1 357 ? -42.597 23.198 -32.544 1.00 66.39 ? 357 ILE A C 1 ATOM 2736 O O . ILE A 1 357 ? -41.650 22.601 -33.052 1.00 64.31 ? 357 ILE A O 1 ATOM 2737 C CB . ILE A 1 357 ? -43.444 22.703 -30.166 1.00 61.63 ? 357 ILE A CB 1 ATOM 2738 C CG1 . ILE A 1 357 ? -42.086 22.210 -29.675 1.00 62.00 ? 357 ILE A CG1 1 ATOM 2739 C CG2 . ILE A 1 357 ? -44.590 22.152 -29.317 1.00 60.90 ? 357 ILE A CG2 1 ATOM 2740 C CD1 . ILE A 1 357 ? -41.395 23.218 -28.754 1.00 74.46 ? 357 ILE A CD1 1 ATOM 2741 N N . VAL A 1 358 ? -42.792 24.520 -32.693 1.00 67.48 ? 358 VAL A N 1 ATOM 2742 C CA . VAL A 1 358 ? -41.831 25.404 -33.349 1.00 69.26 ? 358 VAL A CA 1 ATOM 2743 C C . VAL A 1 358 ? -41.132 26.126 -32.189 1.00 76.52 ? 358 VAL A C 1 ATOM 2744 O O . VAL A 1 358 ? -41.772 26.475 -31.191 1.00 74.89 ? 358 VAL A O 1 ATOM 2745 C CB . VAL A 1 358 ? -42.437 26.414 -34.355 1.00 73.40 ? 358 VAL A CB 1 ATOM 2746 C CG1 . VAL A 1 358 ? -41.333 27.130 -35.140 1.00 72.86 ? 358 VAL A CG1 1 ATOM 2747 C CG2 . VAL A 1 358 ? -43.403 25.727 -35.315 1.00 73.56 ? 358 VAL A CG2 1 ATOM 2748 N N . THR A 1 359 ? -39.813 26.287 -32.297 1.00 76.59 ? 359 THR A N 1 ATOM 2749 C CA . THR A 1 359 ? -38.983 26.962 -31.303 1.00 77.26 ? 359 THR A CA 1 ATOM 2750 C C . THR A 1 359 ? -38.451 28.266 -31.931 1.00 83.32 ? 359 THR A C 1 ATOM 2751 O O . THR A 1 359 ? -38.481 29.317 -31.284 1.00 81.66 ? 359 THR A O 1 ATOM 2752 C CB . THR A 1 359 ? -37.946 25.955 -30.786 1.00 82.05 ? 359 THR A CB 1 ATOM 2753 O OG1 . THR A 1 359 ? -38.611 25.130 -29.834 1.00 76.65 ? 359 THR A OG1 1 ATOM 2754 C CG2 . THR A 1 359 ? -36.687 26.615 -30.175 1.00 81.40 ? 359 THR A CG2 1 ATOM 2755 N N . GLU A 1 360 ? -38.011 28.166 -33.219 1.00 82.80 ? 360 GLU A N 1 ATOM 2756 C CA . GLU A 1 360 ? -37.503 29.232 -34.082 1.00 84.01 ? 360 GLU A CA 1 ATOM 2757 C C . GLU A 1 360 ? -38.053 29.004 -35.493 1.00 89.72 ? 360 GLU A C 1 ATOM 2758 O O . GLU A 1 360 ? -38.051 27.859 -35.971 1.00 89.52 ? 360 GLU A O 1 ATOM 2759 C CB . GLU A 1 360 ? -35.967 29.209 -34.139 1.00 85.67 ? 360 GLU A CB 1 ATOM 2760 C CG . GLU A 1 360 ? -35.277 29.525 -32.827 1.00 99.06 ? 360 GLU A CG 1 ATOM 2761 C CD . GLU A 1 360 ? -33.986 28.757 -32.651 1.00 131.56 ? 360 GLU A CD 1 ATOM 2762 O OE1 . GLU A 1 360 ? -33.095 28.881 -33.526 1.00 129.83 ? 360 GLU A OE1 1 ATOM 2763 O OE2 . GLU A 1 360 ? -33.880 28.002 -31.656 1.00 133.59 ? 360 GLU A OE2 1 ATOM 2764 N N . LYS A 1 361 ? -38.493 30.094 -36.164 1.00 87.18 ? 361 LYS A N 1 ATOM 2765 C CA . LYS A 1 361 ? -39.030 30.066 -37.530 1.00 87.92 ? 361 LYS A CA 1 ATOM 2766 C C . LYS A 1 361 ? -37.980 29.540 -38.510 1.00 94.27 ? 361 LYS A C 1 ATOM 2767 O O . LYS A 1 361 ? -38.315 28.772 -39.419 1.00 94.17 ? 361 LYS A O 1 ATOM 2768 C CB . LYS A 1 361 ? -39.495 31.470 -37.964 1.00 90.58 ? 361 LYS A CB 1 ATOM 2769 C CG . LYS A 1 361 ? -40.991 31.739 -37.831 1.00 105.65 ? 361 LYS A CG 1 ATOM 2770 C CD . LYS A 1 361 ? -41.420 32.270 -36.441 1.00 119.25 ? 361 LYS A CD 1 ATOM 2771 C CE . LYS A 1 361 ? -41.203 33.753 -36.209 1.00 128.29 ? 361 LYS A CE 1 ATOM 2772 N NZ . LYS A 1 361 ? -41.735 34.200 -34.894 1.00 129.28 ? 361 LYS A NZ 1 ATOM 2773 N N . ASP A 1 362 ? -36.712 29.946 -38.300 1.00 92.72 ? 362 ASP A N 1 ATOM 2774 C CA . ASP A 1 362 ? -35.547 29.566 -39.105 1.00 94.07 ? 362 ASP A CA 1 ATOM 2775 C C . ASP A 1 362 ? -35.300 28.048 -39.148 1.00 97.88 ? 362 ASP A C 1 ATOM 2776 O O . ASP A 1 362 ? -34.996 27.500 -40.214 1.00 98.08 ? 362 ASP A O 1 ATOM 2777 C CB . ASP A 1 362 ? -34.283 30.292 -38.590 1.00 97.00 ? 362 ASP A CB 1 ATOM 2778 C CG . ASP A 1 362 ? -34.273 31.808 -38.794 1.00 116.98 ? 362 ASP A CG 1 ATOM 2779 O OD1 . ASP A 1 362 ? -35.355 32.383 -39.127 1.00 118.72 ? 362 ASP A OD1 1 ATOM 2780 O OD2 . ASP A 1 362 ? -33.184 32.423 -38.626 1.00 123.48 ? 362 ASP A OD2 1 ATOM 2781 N N . SER A 1 363 ? -35.431 27.383 -37.984 1.00 92.86 ? 363 SER A N 1 ATOM 2782 C CA . SER A 1 363 ? -35.200 25.952 -37.821 1.00 91.28 ? 363 SER A CA 1 ATOM 2783 C C . SER A 1 363 ? -36.418 25.098 -38.257 1.00 89.51 ? 363 SER A C 1 ATOM 2784 O O . SER A 1 363 ? -37.461 25.138 -37.573 1.00 90.12 ? 363 SER A O 1 ATOM 2785 C CB . SER A 1 363 ? -34.801 25.645 -36.374 1.00 96.43 ? 363 SER A CB 1 ATOM 2786 O OG . SER A 1 363 ? -34.591 24.256 -36.151 1.00 108.39 ? 363 SER A OG 1 ATOM 2787 N N . PRO A 1 364 ? -36.293 24.292 -39.359 1.00 79.09 ? 364 PRO A N 1 ATOM 2788 C CA . PRO A 1 364 ? -37.404 23.419 -39.766 1.00 76.54 ? 364 PRO A CA 1 ATOM 2789 C C . PRO A 1 364 ? -37.635 22.305 -38.754 1.00 73.51 ? 364 PRO A C 1 ATOM 2790 O O . PRO A 1 364 ? -36.811 22.088 -37.870 1.00 72.34 ? 364 PRO A O 1 ATOM 2791 C CB . PRO A 1 364 ? -36.968 22.868 -41.132 1.00 78.34 ? 364 PRO A CB 1 ATOM 2792 C CG . PRO A 1 364 ? -35.823 23.674 -41.534 1.00 83.41 ? 364 PRO A CG 1 ATOM 2793 C CD . PRO A 1 364 ? -35.159 24.138 -40.280 1.00 79.35 ? 364 PRO A CD 1 ATOM 2794 N N . VAL A 1 365 ? -38.784 21.642 -38.861 1.00 65.43 ? 365 VAL A N 1 ATOM 2795 C CA . VAL A 1 365 ? -39.203 20.595 -37.952 1.00 63.17 ? 365 VAL A CA 1 ATOM 2796 C C . VAL A 1 365 ? -39.445 19.284 -38.711 1.00 64.61 ? 365 VAL A C 1 ATOM 2797 O O . VAL A 1 365 ? -39.936 19.289 -39.836 1.00 63.63 ? 365 VAL A O 1 ATOM 2798 C CB . VAL A 1 365 ? -40.451 21.043 -37.115 1.00 65.96 ? 365 VAL A CB 1 ATOM 2799 C CG1 . VAL A 1 365 ? -40.997 19.909 -36.234 1.00 65.30 ? 365 VAL A CG1 1 ATOM 2800 C CG2 . VAL A 1 365 ? -40.168 22.293 -36.278 1.00 65.39 ? 365 VAL A CG2 1 ATOM 2801 N N . ASN A 1 366 ? -39.136 18.169 -38.052 1.00 59.43 ? 366 ASN A N 1 ATOM 2802 C CA . ASN A 1 366 ? -39.342 16.826 -38.547 1.00 58.64 ? 366 ASN A CA 1 ATOM 2803 C C . ASN A 1 366 ? -40.451 16.135 -37.749 1.00 61.91 ? 366 ASN A C 1 ATOM 2804 O O . ASN A 1 366 ? -40.386 16.061 -36.514 1.00 62.07 ? 366 ASN A O 1 ATOM 2805 C CB . ASN A 1 366 ? -38.063 16.037 -38.450 1.00 58.49 ? 366 ASN A CB 1 ATOM 2806 C CG . ASN A 1 366 ? -37.041 16.478 -39.432 1.00 75.24 ? 366 ASN A CG 1 ATOM 2807 O OD1 . ASN A 1 366 ? -37.092 16.125 -40.615 1.00 72.33 ? 366 ASN A OD1 1 ATOM 2808 N ND2 . ASN A 1 366 ? -36.100 17.255 -38.960 1.00 61.80 ? 366 ASN A ND2 1 ATOM 2809 N N . ILE A 1 367 ? -41.476 15.640 -38.449 1.00 55.36 ? 367 ILE A N 1 ATOM 2810 C CA . ILE A 1 367 ? -42.595 14.977 -37.802 1.00 52.75 ? 367 ILE A CA 1 ATOM 2811 C C . ILE A 1 367 ? -42.726 13.572 -38.339 1.00 54.56 ? 367 ILE A C 1 ATOM 2812 O O . ILE A 1 367 ? -42.729 13.365 -39.552 1.00 53.45 ? 367 ILE A O 1 ATOM 2813 C CB . ILE A 1 367 ? -43.924 15.781 -37.914 1.00 55.39 ? 367 ILE A CB 1 ATOM 2814 C CG1 . ILE A 1 367 ? -43.788 17.212 -37.396 1.00 54.54 ? 367 ILE A CG1 1 ATOM 2815 C CG2 . ILE A 1 367 ? -45.079 15.075 -37.180 1.00 58.65 ? 367 ILE A CG2 1 ATOM 2816 C CD1 . ILE A 1 367 ? -43.967 18.197 -38.424 1.00 56.83 ? 367 ILE A CD1 1 ATOM 2817 N N . GLU A 1 368 ? -42.830 12.606 -37.417 1.00 50.51 ? 368 GLU A N 1 ATOM 2818 C CA . GLU A 1 368 ? -43.054 11.204 -37.737 1.00 49.89 ? 368 GLU A CA 1 ATOM 2819 C C . GLU A 1 368 ? -44.423 10.836 -37.238 1.00 49.85 ? 368 GLU A C 1 ATOM 2820 O O . GLU A 1 368 ? -44.738 11.050 -36.062 1.00 46.46 ? 368 GLU A O 1 ATOM 2821 C CB . GLU A 1 368 ? -41.996 10.279 -37.110 1.00 51.84 ? 368 GLU A CB 1 ATOM 2822 C CG . GLU A 1 368 ? -42.090 8.837 -37.613 1.00 64.72 ? 368 GLU A CG 1 ATOM 2823 C CD . GLU A 1 368 ? -41.137 7.801 -37.035 1.00 88.86 ? 368 GLU A CD 1 ATOM 2824 O OE1 . GLU A 1 368 ? -40.849 7.847 -35.818 1.00 79.19 ? 368 GLU A OE1 1 ATOM 2825 O OE2 . GLU A 1 368 ? -40.710 6.907 -37.797 1.00 90.18 ? 368 GLU A OE2 1 ATOM 2826 N N . ALA A 1 369 ? -45.233 10.265 -38.146 1.00 46.39 ? 369 ALA A N 1 ATOM 2827 C CA . ALA A 1 369 ? -46.596 9.807 -37.853 1.00 45.68 ? 369 ALA A CA 1 ATOM 2828 C C . ALA A 1 369 ? -46.890 8.494 -38.538 1.00 46.85 ? 369 ALA A C 1 ATOM 2829 O O . ALA A 1 369 ? -46.296 8.197 -39.575 1.00 44.67 ? 369 ALA A O 1 ATOM 2830 C CB . ALA A 1 369 ? -47.611 10.850 -38.291 1.00 46.61 ? 369 ALA A CB 1 ATOM 2831 N N . GLU A 1 370 ? -47.813 7.724 -37.957 1.00 45.13 ? 370 GLU A N 1 ATOM 2832 C CA . GLU A 1 370 ? -48.271 6.452 -38.502 1.00 47.44 ? 370 GLU A CA 1 ATOM 2833 C C . GLU A 1 370 ? -49.592 6.688 -39.285 1.00 54.94 ? 370 GLU A C 1 ATOM 2834 O O . GLU A 1 370 ? -50.656 6.844 -38.654 1.00 54.81 ? 370 GLU A O 1 ATOM 2835 C CB . GLU A 1 370 ? -48.468 5.383 -37.392 1.00 48.94 ? 370 GLU A CB 1 ATOM 2836 C CG . GLU A 1 370 ? -48.797 3.992 -37.920 1.00 55.13 ? 370 GLU A CG 1 ATOM 2837 C CD . GLU A 1 370 ? -48.223 2.856 -37.097 1.00 86.48 ? 370 GLU A CD 1 ATOM 2838 O OE1 . GLU A 1 370 ? -48.226 2.950 -35.844 1.00 87.92 ? 370 GLU A OE1 1 ATOM 2839 O OE2 . GLU A 1 370 ? -47.767 1.865 -37.713 1.00 82.71 ? 370 GLU A OE2 1 ATOM 2840 N N . PRO A 1 371 ? -49.548 6.716 -40.650 1.00 50.94 ? 371 PRO A N 1 ATOM 2841 C CA . PRO A 1 371 ? -50.790 6.897 -41.408 1.00 50.08 ? 371 PRO A CA 1 ATOM 2842 C C . PRO A 1 371 ? -51.666 5.639 -41.375 1.00 54.99 ? 371 PRO A C 1 ATOM 2843 O O . PRO A 1 371 ? -51.123 4.549 -41.187 1.00 54.12 ? 371 PRO A O 1 ATOM 2844 C CB . PRO A 1 371 ? -50.293 7.189 -42.823 1.00 51.29 ? 371 PRO A CB 1 ATOM 2845 C CG . PRO A 1 371 ? -48.999 6.510 -42.913 1.00 56.05 ? 371 PRO A CG 1 ATOM 2846 C CD . PRO A 1 371 ? -48.389 6.550 -41.551 1.00 51.95 ? 371 PRO A CD 1 ATOM 2847 N N . PRO A 1 372 ? -53.007 5.741 -41.573 1.00 53.32 ? 372 PRO A N 1 ATOM 2848 C CA . PRO A 1 372 ? -53.828 4.527 -41.643 1.00 53.59 ? 372 PRO A CA 1 ATOM 2849 C C . PRO A 1 372 ? -53.666 3.797 -42.978 1.00 60.51 ? 372 PRO A C 1 ATOM 2850 O O . PRO A 1 372 ? -53.235 4.394 -43.982 1.00 61.10 ? 372 PRO A O 1 ATOM 2851 C CB . PRO A 1 372 ? -55.245 5.073 -41.520 1.00 54.99 ? 372 PRO A CB 1 ATOM 2852 C CG . PRO A 1 372 ? -55.183 6.395 -42.150 1.00 59.11 ? 372 PRO A CG 1 ATOM 2853 C CD . PRO A 1 372 ? -53.837 6.945 -41.794 1.00 54.80 ? 372 PRO A CD 1 ATOM 2854 N N . PHE A 1 373 ? -54.030 2.504 -42.991 1.00 58.29 ? 373 PHE A N 1 ATOM 2855 C CA . PHE A 1 373 ? -53.978 1.686 -44.197 1.00 58.08 ? 373 PHE A CA 1 ATOM 2856 C C . PHE A 1 373 ? -54.959 2.209 -45.217 1.00 59.97 ? 373 PHE A C 1 ATOM 2857 O O . PHE A 1 373 ? -56.147 2.286 -44.952 1.00 60.17 ? 373 PHE A O 1 ATOM 2858 C CB . PHE A 1 373 ? -54.194 0.189 -43.895 1.00 60.31 ? 373 PHE A CB 1 ATOM 2859 C CG . PHE A 1 373 ? -52.903 -0.501 -43.512 1.00 62.37 ? 373 PHE A CG 1 ATOM 2860 C CD1 . PHE A 1 373 ? -51.957 -0.828 -44.481 1.00 66.49 ? 373 PHE A CD1 1 ATOM 2861 C CD2 . PHE A 1 373 ? -52.603 -0.767 -42.178 1.00 63.73 ? 373 PHE A CD2 1 ATOM 2862 C CE1 . PHE A 1 373 ? -50.728 -1.389 -44.119 1.00 67.44 ? 373 PHE A CE1 1 ATOM 2863 C CE2 . PHE A 1 373 ? -51.372 -1.318 -41.818 1.00 66.37 ? 373 PHE A CE2 1 ATOM 2864 C CZ . PHE A 1 373 ? -50.450 -1.639 -42.790 1.00 65.33 ? 373 PHE A CZ 1 ATOM 2865 N N . GLY A 1 374 ? -54.436 2.625 -46.348 1.00 55.13 ? 374 GLY A N 1 ATOM 2866 C CA . GLY A 1 374 ? -55.223 3.164 -47.437 1.00 54.27 ? 374 GLY A CA 1 ATOM 2867 C C . GLY A 1 374 ? -55.037 4.651 -47.573 1.00 56.37 ? 374 GLY A C 1 ATOM 2868 O O . GLY A 1 374 ? -53.998 5.206 -47.168 1.00 54.05 ? 374 GLY A O 1 ATOM 2869 N N . ASP A 1 375 ? -56.077 5.301 -48.127 1.00 52.83 ? 375 ASP A N 1 ATOM 2870 C CA . ASP A 1 375 ? -56.048 6.735 -48.353 1.00 52.26 ? 375 ASP A CA 1 ATOM 2871 C C . ASP A 1 375 ? -56.369 7.537 -47.099 1.00 55.79 ? 375 ASP A C 1 ATOM 2872 O O . ASP A 1 375 ? -57.252 7.169 -46.304 1.00 54.16 ? 375 ASP A O 1 ATOM 2873 C CB . ASP A 1 375 ? -56.921 7.168 -49.537 1.00 53.60 ? 375 ASP A CB 1 ATOM 2874 C CG . ASP A 1 375 ? -56.389 6.765 -50.895 1.00 66.16 ? 375 ASP A CG 1 ATOM 2875 O OD1 . ASP A 1 375 ? -55.328 7.295 -51.307 1.00 68.72 ? 375 ASP A OD1 1 ATOM 2876 O OD2 . ASP A 1 375 ? -57.061 5.965 -51.575 1.00 69.69 ? 375 ASP A OD2 1 ATOM 2877 N N . SER A 1 376 ? -55.582 8.621 -46.917 1.00 50.78 ? 376 SER A N 1 ATOM 2878 C CA . SER A 1 376 ? -55.708 9.582 -45.836 1.00 48.70 ? 376 SER A CA 1 ATOM 2879 C C . SER A 1 376 ? -55.224 10.941 -46.320 1.00 50.17 ? 376 SER A C 1 ATOM 2880 O O . SER A 1 376 ? -54.695 11.053 -47.429 1.00 48.24 ? 376 SER A O 1 ATOM 2881 C CB . SER A 1 376 ? -54.924 9.123 -44.611 1.00 49.68 ? 376 SER A CB 1 ATOM 2882 O OG . SER A 1 376 ? -53.600 8.722 -44.916 1.00 52.00 ? 376 SER A OG 1 ATOM 2883 N N . TYR A 1 377 ? -55.466 11.971 -45.507 1.00 46.92 ? 377 TYR A N 1 ATOM 2884 C CA . TYR A 1 377 ? -55.014 13.334 -45.723 1.00 47.01 ? 377 TYR A CA 1 ATOM 2885 C C . TYR A 1 377 ? -54.122 13.742 -44.561 1.00 50.07 ? 377 TYR A C 1 ATOM 2886 O O . TYR A 1 377 ? -54.531 13.675 -43.388 1.00 50.65 ? 377 TYR A O 1 ATOM 2887 C CB . TYR A 1 377 ? -56.176 14.330 -45.835 1.00 48.85 ? 377 TYR A CB 1 ATOM 2888 C CG . TYR A 1 377 ? -56.624 14.621 -47.250 1.00 54.22 ? 377 TYR A CG 1 ATOM 2889 C CD1 . TYR A 1 377 ? -55.822 15.357 -48.125 1.00 55.74 ? 377 TYR A CD1 1 ATOM 2890 C CD2 . TYR A 1 377 ? -57.870 14.201 -47.708 1.00 57.33 ? 377 TYR A CD2 1 ATOM 2891 C CE1 . TYR A 1 377 ? -56.230 15.622 -49.433 1.00 56.56 ? 377 TYR A CE1 1 ATOM 2892 C CE2 . TYR A 1 377 ? -58.301 14.488 -49.003 1.00 59.00 ? 377 TYR A CE2 1 ATOM 2893 C CZ . TYR A 1 377 ? -57.485 15.211 -49.856 1.00 66.68 ? 377 TYR A CZ 1 ATOM 2894 O OH . TYR A 1 377 ? -57.927 15.490 -51.128 1.00 72.71 ? 377 TYR A OH 1 ATOM 2895 N N . ILE A 1 378 ? -52.893 14.114 -44.874 1.00 43.60 ? 378 ILE A N 1 ATOM 2896 C CA . ILE A 1 378 ? -51.987 14.630 -43.868 1.00 42.47 ? 378 ILE A CA 1 ATOM 2897 C C . ILE A 1 378 ? -52.148 16.140 -43.901 1.00 48.85 ? 378 ILE A C 1 ATOM 2898 O O . ILE A 1 378 ? -51.784 16.802 -44.873 1.00 48.03 ? 378 ILE A O 1 ATOM 2899 C CB . ILE A 1 378 ? -50.541 14.141 -44.007 1.00 43.74 ? 378 ILE A CB 1 ATOM 2900 C CG1 . ILE A 1 378 ? -50.490 12.648 -43.689 1.00 43.73 ? 378 ILE A CG1 1 ATOM 2901 C CG2 . ILE A 1 378 ? -49.605 14.935 -43.070 1.00 41.03 ? 378 ILE A CG2 1 ATOM 2902 C CD1 . ILE A 1 378 ? -49.568 11.907 -44.508 1.00 54.20 ? 378 ILE A CD1 1 ATOM 2903 N N . ILE A 1 379 ? -52.751 16.655 -42.845 1.00 47.04 ? 379 ILE A N 1 ATOM 2904 C CA . ILE A 1 379 ? -53.055 18.060 -42.678 1.00 47.83 ? 379 ILE A CA 1 ATOM 2905 C C . ILE A 1 379 ? -52.140 18.695 -41.600 1.00 54.66 ? 379 ILE A C 1 ATOM 2906 O O . ILE A 1 379 ? -52.256 18.464 -40.383 1.00 53.97 ? 379 ILE A O 1 ATOM 2907 C CB . ILE A 1 379 ? -54.592 18.263 -42.442 1.00 50.81 ? 379 ILE A CB 1 ATOM 2908 C CG1 . ILE A 1 379 ? -55.428 17.771 -43.659 1.00 49.51 ? 379 ILE A CG1 1 ATOM 2909 C CG2 . ILE A 1 379 ? -54.932 19.715 -42.079 1.00 52.66 ? 379 ILE A CG2 1 ATOM 2910 C CD1 . ILE A 1 379 ? -56.702 17.052 -43.301 1.00 38.60 ? 379 ILE A CD1 1 ATOM 2911 N N . VAL A 1 380 ? -51.214 19.491 -42.083 1.00 53.98 ? 380 VAL A N 1 ATOM 2912 C CA . VAL A 1 380 ? -50.295 20.200 -41.224 1.00 54.88 ? 380 VAL A CA 1 ATOM 2913 C C . VAL A 1 380 ? -50.554 21.702 -41.340 1.00 59.67 ? 380 VAL A C 1 ATOM 2914 O O . VAL A 1 380 ? -50.540 22.286 -42.422 1.00 56.46 ? 380 VAL A O 1 ATOM 2915 C CB . VAL A 1 380 ? -48.824 19.773 -41.397 1.00 59.51 ? 380 VAL A CB 1 ATOM 2916 C CG1 . VAL A 1 380 ? -48.390 19.767 -42.857 1.00 59.61 ? 380 VAL A CG1 1 ATOM 2917 C CG2 . VAL A 1 380 ? -47.889 20.616 -40.537 1.00 59.52 ? 380 VAL A CG2 1 ATOM 2918 N N . GLY A 1 381 ? -50.844 22.282 -40.195 1.00 60.20 ? 381 GLY A N 1 ATOM 2919 C CA . GLY A 1 381 ? -51.130 23.690 -40.068 1.00 61.70 ? 381 GLY A CA 1 ATOM 2920 C C . GLY A 1 381 ? -52.600 23.979 -40.021 1.00 69.84 ? 381 GLY A C 1 ATOM 2921 O O . GLY A 1 381 ? -53.427 23.058 -39.945 1.00 70.80 ? 381 GLY A O 1 ATOM 2922 N N . VAL A 1 382 ? -52.911 25.280 -40.047 1.00 67.94 ? 382 VAL A N 1 ATOM 2923 C CA . VAL A 1 382 ? -54.254 25.816 -39.989 1.00 68.53 ? 382 VAL A CA 1 ATOM 2924 C C . VAL A 1 382 ? -54.480 26.760 -41.167 1.00 77.58 ? 382 VAL A C 1 ATOM 2925 O O . VAL A 1 382 ? -53.509 27.341 -41.683 1.00 77.63 ? 382 VAL A O 1 ATOM 2926 C CB . VAL A 1 382 ? -54.523 26.412 -38.579 1.00 70.95 ? 382 VAL A CB 1 ATOM 2927 C CG1 . VAL A 1 382 ? -55.094 27.826 -38.593 1.00 70.82 ? 382 VAL A CG1 1 ATOM 2928 C CG2 . VAL A 1 382 ? -55.393 25.470 -37.779 1.00 70.20 ? 382 VAL A CG2 1 ATOM 2929 N N . GLU A 1 383 ? -55.767 26.838 -41.624 1.00 76.66 ? 383 GLU A N 1 ATOM 2930 C CA . GLU A 1 383 ? -56.269 27.658 -42.738 1.00 76.92 ? 383 GLU A CA 1 ATOM 2931 C C . GLU A 1 383 ? -56.136 29.167 -42.444 1.00 82.77 ? 383 GLU A C 1 ATOM 2932 O O . GLU A 1 383 ? -56.462 29.569 -41.321 1.00 83.12 ? 383 GLU A O 1 ATOM 2933 C CB . GLU A 1 383 ? -57.731 27.280 -43.082 1.00 77.69 ? 383 GLU A CB 1 ATOM 2934 C CG . GLU A 1 383 ? -57.858 26.264 -44.206 1.00 80.50 ? 383 GLU A CG 1 ATOM 2935 C CD . GLU A 1 383 ? -57.439 26.769 -45.575 1.00 102.38 ? 383 GLU A CD 1 ATOM 2936 O OE1 . GLU A 1 383 ? -58.265 27.456 -46.215 1.00 118.19 ? 383 GLU A OE1 1 ATOM 2937 O OE2 . GLU A 1 383 ? -56.289 26.507 -46.000 1.00 84.38 ? 383 GLU A OE2 1 ATOM 2938 N N . PRO A 1 384 ? -55.669 30.031 -43.395 1.00 79.06 ? 384 PRO A N 1 ATOM 2939 C CA . PRO A 1 384 ? -55.227 29.763 -44.789 1.00 78.29 ? 384 PRO A CA 1 ATOM 2940 C C . PRO A 1 384 ? -53.810 29.201 -44.842 1.00 80.18 ? 384 PRO A C 1 ATOM 2941 O O . PRO A 1 384 ? -53.109 29.237 -43.831 1.00 82.32 ? 384 PRO A O 1 ATOM 2942 C CB . PRO A 1 384 ? -55.263 31.156 -45.425 1.00 80.25 ? 384 PRO A CB 1 ATOM 2943 C CG . PRO A 1 384 ? -54.902 32.075 -44.296 1.00 84.75 ? 384 PRO A CG 1 ATOM 2944 C CD . PRO A 1 384 ? -55.537 31.466 -43.063 1.00 80.48 ? 384 PRO A CD 1 ATOM 2945 N N . GLY A 1 385 ? -53.378 28.739 -46.008 1.00 72.35 ? 385 GLY A N 1 ATOM 2946 C CA . GLY A 1 385 ? -52.044 28.163 -46.150 1.00 70.60 ? 385 GLY A CA 1 ATOM 2947 C C . GLY A 1 385 ? -51.888 26.813 -45.465 1.00 71.03 ? 385 GLY A C 1 ATOM 2948 O O . GLY A 1 385 ? -50.764 26.317 -45.310 1.00 72.56 ? 385 GLY A O 1 ATOM 2949 N N . GLN A 1 386 ? -53.036 26.210 -45.053 1.00 61.40 ? 386 GLN A N 1 ATOM 2950 C CA . GLN A 1 386 ? -53.145 24.897 -44.445 1.00 57.75 ? 386 GLN A CA 1 ATOM 2951 C C . GLN A 1 386 ? -52.625 23.952 -45.488 1.00 61.96 ? 386 GLN A C 1 ATOM 2952 O O . GLN A 1 386 ? -53.039 24.066 -46.648 1.00 62.54 ? 386 GLN A O 1 ATOM 2953 C CB . GLN A 1 386 ? -54.616 24.578 -44.191 1.00 56.92 ? 386 GLN A CB 1 ATOM 2954 C CG . GLN A 1 386 ? -54.849 23.472 -43.208 1.00 45.74 ? 386 GLN A CG 1 ATOM 2955 C CD . GLN A 1 386 ? -56.222 22.852 -43.321 1.00 65.61 ? 386 GLN A CD 1 ATOM 2956 O OE1 . GLN A 1 386 ? -56.726 22.559 -44.405 1.00 66.60 ? 386 GLN A OE1 1 ATOM 2957 N NE2 . GLN A 1 386 ? -56.842 22.559 -42.196 1.00 52.14 ? 386 GLN A NE2 1 ATOM 2958 N N . LEU A 1 387 ? -51.658 23.089 -45.110 1.00 58.16 ? 387 LEU A N 1 ATOM 2959 C CA . LEU A 1 387 ? -51.079 22.061 -45.980 1.00 57.36 ? 387 LEU A CA 1 ATOM 2960 C C . LEU A 1 387 ? -51.982 20.813 -45.906 1.00 64.20 ? 387 LEU A C 1 ATOM 2961 O O . LEU A 1 387 ? -52.315 20.341 -44.814 1.00 62.54 ? 387 LEU A O 1 ATOM 2962 C CB . LEU A 1 387 ? -49.622 21.739 -45.631 1.00 56.25 ? 387 LEU A CB 1 ATOM 2963 C CG . LEU A 1 387 ? -48.601 22.853 -45.829 1.00 60.39 ? 387 LEU A CG 1 ATOM 2964 C CD1 . LEU A 1 387 ? -47.251 22.453 -45.263 1.00 61.13 ? 387 LEU A CD1 1 ATOM 2965 C CD2 . LEU A 1 387 ? -48.406 23.163 -47.284 1.00 62.59 ? 387 LEU A CD2 1 ATOM 2966 N N . LYS A 1 388 ? -52.481 20.371 -47.072 1.00 63.46 ? 388 LYS A N 1 ATOM 2967 C CA . LYS A 1 388 ? -53.396 19.236 -47.163 1.00 63.78 ? 388 LYS A CA 1 ATOM 2968 C C . LYS A 1 388 ? -52.772 18.190 -48.106 1.00 69.31 ? 388 LYS A C 1 ATOM 2969 O O . LYS A 1 388 ? -53.072 18.143 -49.297 1.00 69.19 ? 388 LYS A O 1 ATOM 2970 C CB . LYS A 1 388 ? -54.803 19.682 -47.624 1.00 65.27 ? 388 LYS A CB 1 ATOM 2971 C CG . LYS A 1 388 ? -55.325 20.982 -46.997 1.00 79.21 ? 388 LYS A CG 1 ATOM 2972 C CD . LYS A 1 388 ? -56.394 21.655 -47.868 1.00 97.29 ? 388 LYS A CD 1 ATOM 2973 C CE . LYS A 1 388 ? -56.685 23.104 -47.531 1.00 116.49 ? 388 LYS A CE 1 ATOM 2974 N NZ . LYS A 1 388 ? -55.631 24.048 -48.003 1.00 130.12 ? 388 LYS A NZ 1 ATOM 2975 N N . LEU A 1 389 ? -51.856 17.391 -47.557 1.00 66.25 ? 389 LEU A N 1 ATOM 2976 C CA . LEU A 1 389 ? -51.131 16.336 -48.268 1.00 66.05 ? 389 LEU A CA 1 ATOM 2977 C C . LEU A 1 389 ? -51.933 15.044 -48.289 1.00 67.76 ? 389 LEU A C 1 ATOM 2978 O O . LEU A 1 389 ? -52.733 14.800 -47.399 1.00 66.51 ? 389 LEU A O 1 ATOM 2979 C CB . LEU A 1 389 ? -49.739 16.119 -47.650 1.00 66.24 ? 389 LEU A CB 1 ATOM 2980 C CG . LEU A 1 389 ? -48.841 17.373 -47.635 1.00 70.86 ? 389 LEU A CG 1 ATOM 2981 C CD1 . LEU A 1 389 ? -47.827 17.337 -46.487 1.00 69.66 ? 389 LEU A CD1 1 ATOM 2982 C CD2 . LEU A 1 389 ? -48.175 17.598 -48.997 1.00 73.57 ? 389 LEU A CD2 1 ATOM 2983 N N . ASN A 1 390 ? -51.738 14.236 -49.325 1.00 63.06 ? 390 ASN A N 1 ATOM 2984 C CA . ASN A 1 390 ? -52.467 12.991 -49.529 1.00 62.17 ? 390 ASN A CA 1 ATOM 2985 C C . ASN A 1 390 ? -51.542 11.807 -49.471 1.00 64.27 ? 390 ASN A C 1 ATOM 2986 O O . ASN A 1 390 ? -50.475 11.813 -50.095 1.00 64.68 ? 390 ASN A O 1 ATOM 2987 C CB . ASN A 1 390 ? -53.204 13.015 -50.857 1.00 64.41 ? 390 ASN A CB 1 ATOM 2988 C CG . ASN A 1 390 ? -52.548 13.845 -51.933 1.00 112.79 ? 390 ASN A CG 1 ATOM 2989 O OD1 . ASN A 1 390 ? -51.309 13.948 -52.033 1.00 108.92 ? 390 ASN A OD1 1 ATOM 2990 N ND2 . ASN A 1 390 ? -53.381 14.486 -52.745 1.00 113.52 ? 390 ASN A ND2 1 ATOM 2991 N N . TRP A 1 391 ? -51.963 10.778 -48.734 1.00 58.05 ? 391 TRP A N 1 ATOM 2992 C CA . TRP A 1 391 ? -51.168 9.589 -48.546 1.00 56.43 ? 391 TRP A CA 1 ATOM 2993 C C . TRP A 1 391 ? -51.908 8.303 -48.853 1.00 62.32 ? 391 TRP A C 1 ATOM 2994 O O . TRP A 1 391 ? -53.126 8.217 -48.671 1.00 63.37 ? 391 TRP A O 1 ATOM 2995 C CB . TRP A 1 391 ? -50.581 9.552 -47.111 1.00 53.77 ? 391 TRP A CB 1 ATOM 2996 C CG . TRP A 1 391 ? -49.424 8.602 -46.969 1.00 53.66 ? 391 TRP A CG 1 ATOM 2997 C CD1 . TRP A 1 391 ? -49.414 7.399 -46.321 1.00 56.21 ? 391 TRP A CD1 1 ATOM 2998 C CD2 . TRP A 1 391 ? -48.166 8.704 -47.642 1.00 52.91 ? 391 TRP A CD2 1 ATOM 2999 N NE1 . TRP A 1 391 ? -48.201 6.775 -46.501 1.00 55.06 ? 391 TRP A NE1 1 ATOM 3000 C CE2 . TRP A 1 391 ? -47.439 7.531 -47.353 1.00 56.34 ? 391 TRP A CE2 1 ATOM 3001 C CE3 . TRP A 1 391 ? -47.598 9.663 -48.496 1.00 53.47 ? 391 TRP A CE3 1 ATOM 3002 C CZ2 . TRP A 1 391 ? -46.172 7.304 -47.876 1.00 55.54 ? 391 TRP A CZ2 1 ATOM 3003 C CZ3 . TRP A 1 391 ? -46.342 9.434 -49.008 1.00 54.46 ? 391 TRP A CZ3 1 ATOM 3004 C CH2 . TRP A 1 391 ? -45.630 8.287 -48.671 1.00 55.13 ? 391 TRP A CH2 1 ATOM 3005 N N . LEU A 1 392 ? -51.136 7.302 -49.275 1.00 58.74 ? 392 LEU A N 1 ATOM 3006 C CA . LEU A 1 392 ? -51.627 5.970 -49.527 1.00 59.06 ? 392 LEU A CA 1 ATOM 3007 C C . LEU A 1 392 ? -50.762 4.943 -48.793 1.00 67.88 ? 392 LEU A C 1 ATOM 3008 O O . LEU A 1 392 ? -49.538 5.016 -48.867 1.00 68.56 ? 392 LEU A O 1 ATOM 3009 C CB . LEU A 1 392 ? -51.631 5.715 -51.019 1.00 58.08 ? 392 LEU A CB 1 ATOM 3010 C CG . LEU A 1 392 ? -52.167 4.397 -51.427 1.00 61.07 ? 392 LEU A CG 1 ATOM 3011 C CD1 . LEU A 1 392 ? -53.662 4.333 -51.215 1.00 61.12 ? 392 LEU A CD1 1 ATOM 3012 C CD2 . LEU A 1 392 ? -51.813 4.129 -52.823 1.00 62.25 ? 392 LEU A CD2 1 ATOM 3013 N N . ARG A 1 393 ? -51.385 4.019 -48.059 1.00 67.19 ? 393 ARG A N 1 ATOM 3014 C CA . ARG A 1 393 ? -50.638 2.983 -47.353 1.00 68.88 ? 393 ARG A CA 1 ATOM 3015 C C . ARG A 1 393 ? -51.281 1.676 -47.736 1.00 78.48 ? 393 ARG A C 1 ATOM 3016 O O . ARG A 1 393 ? -52.281 1.273 -47.149 1.00 79.16 ? 393 ARG A O 1 ATOM 3017 C CB . ARG A 1 393 ? -50.627 3.198 -45.827 1.00 68.64 ? 393 ARG A CB 1 ATOM 3018 C CG . ARG A 1 393 ? -49.741 2.211 -45.088 1.00 70.98 ? 393 ARG A CG 1 ATOM 3019 C CD . ARG A 1 393 ? -49.937 2.265 -43.590 1.00 77.67 ? 393 ARG A CD 1 ATOM 3020 N NE . ARG A 1 393 ? -48.972 1.382 -42.932 1.00 86.99 ? 393 ARG A NE 1 ATOM 3021 C CZ . ARG A 1 393 ? -48.918 1.130 -41.626 1.00 86.20 ? 393 ARG A CZ 1 ATOM 3022 N NH1 . ARG A 1 393 ? -49.798 1.682 -40.798 1.00 72.68 ? 393 ARG A NH1 1 ATOM 3023 N NH2 . ARG A 1 393 ? -48.002 0.301 -41.141 1.00 55.43 ? 393 ARG A NH2 1 ATOM 3024 N N . PRO A 1 394 ? -50.783 1.016 -48.784 1.00 78.53 ? 394 PRO A N 1 ATOM 3025 C CA . PRO A 1 394 ? -51.450 -0.231 -49.218 1.00 78.75 ? 394 PRO A CA 1 ATOM 3026 C C . PRO A 1 394 ? -51.336 -1.378 -48.218 1.00 83.77 ? 394 PRO A C 1 ATOM 3027 O O . PRO A 1 394 ? -50.434 -1.360 -47.368 1.00 84.03 ? 394 PRO A O 1 ATOM 3028 C CB . PRO A 1 394 ? -50.770 -0.552 -50.542 1.00 80.75 ? 394 PRO A CB 1 ATOM 3029 C CG . PRO A 1 394 ? -49.415 0.141 -50.454 1.00 85.67 ? 394 PRO A CG 1 ATOM 3030 C CD . PRO A 1 394 ? -49.620 1.368 -49.633 1.00 80.88 ? 394 PRO A CD 1 ATOM 3031 N N . LEU A 1 395 ? -52.242 -2.374 -48.324 1.00 80.32 ? 395 LEU A N 1 ATOM 3032 C CA . LEU A 1 395 ? -52.238 -3.543 -47.437 1.00 115.00 ? 395 LEU A CA 1 ATOM 3033 C C . LEU A 1 395 ? -51.299 -4.652 -47.950 1.00 151.66 ? 395 LEU A C 1 ATOM 3034 O O . LEU A 1 395 ? -50.125 -4.714 -47.568 1.00 112.85 ? 395 LEU A O 1 ATOM 3035 C CB . LEU A 1 395 ? -53.662 -4.079 -47.243 1.00 114.94 ? 395 LEU A CB 1 ATOM 3036 N N . MET B 1 1 ? 28.211 -55.170 -47.512 1.00 73.93 ? 1 MET B N 1 ATOM 3037 C CA . MET B 1 1 ? 28.972 -54.616 -46.394 1.00 74.66 ? 1 MET B CA 1 ATOM 3038 C C . MET B 1 1 ? 28.317 -53.359 -45.807 1.00 79.55 ? 1 MET B C 1 ATOM 3039 O O . MET B 1 1 ? 28.832 -52.793 -44.841 1.00 77.15 ? 1 MET B O 1 ATOM 3040 C CB . MET B 1 1 ? 30.420 -54.352 -46.802 1.00 77.60 ? 1 MET B CB 1 ATOM 3041 C CG . MET B 1 1 ? 31.056 -55.507 -47.593 1.00 82.31 ? 1 MET B CG 1 ATOM 3042 S SD . MET B 1 1 ? 32.242 -56.518 -46.667 1.00 86.96 ? 1 MET B SD 1 ATOM 3043 C CE . MET B 1 1 ? 33.584 -55.299 -46.397 1.00 82.61 ? 1 MET B CE 1 ATOM 3044 N N . ARG B 1 2 ? 27.164 -52.940 -46.403 1.00 78.99 ? 2 ARG B N 1 ATOM 3045 C CA . ARG B 1 2 ? 26.333 -51.799 -45.987 1.00 79.25 ? 2 ARG B CA 1 ATOM 3046 C C . ARG B 1 2 ? 25.656 -52.121 -44.662 1.00 80.76 ? 2 ARG B C 1 ATOM 3047 O O . ARG B 1 2 ? 25.654 -51.282 -43.771 1.00 78.69 ? 2 ARG B O 1 ATOM 3048 C CB . ARG B 1 2 ? 25.227 -51.520 -47.024 1.00 84.08 ? 2 ARG B CB 1 ATOM 3049 C CG . ARG B 1 2 ? 25.679 -50.828 -48.297 1.00 109.15 ? 2 ARG B CG 1 ATOM 3050 C CD . ARG B 1 2 ? 24.511 -50.612 -49.267 1.00 131.30 ? 2 ARG B CD 1 ATOM 3051 N NE . ARG B 1 2 ? 24.555 -49.266 -49.853 1.00 143.55 ? 2 ARG B NE 1 ATOM 3052 C CZ . ARG B 1 2 ? 23.711 -48.283 -49.550 1.00 152.11 ? 2 ARG B CZ 1 ATOM 3053 N NH1 . ARG B 1 2 ? 22.716 -48.493 -48.697 1.00 140.21 ? 2 ARG B NH1 1 ATOM 3054 N NH2 . ARG B 1 2 ? 23.851 -47.085 -50.106 1.00 131.82 ? 2 ARG B NH2 1 ATOM 3055 N N . CYS B 1 3 ? 25.085 -53.345 -44.549 1.00 77.72 ? 3 CYS B N 1 ATOM 3056 C CA . CYS B 1 3 ? 24.367 -53.875 -43.399 1.00 78.22 ? 3 CYS B CA 1 ATOM 3057 C C . CYS B 1 3 ? 25.150 -53.817 -42.103 1.00 78.87 ? 3 CYS B C 1 ATOM 3058 O O . CYS B 1 3 ? 24.534 -53.738 -41.036 1.00 79.53 ? 3 CYS B O 1 ATOM 3059 C CB . CYS B 1 3 ? 23.875 -55.288 -43.671 1.00 80.60 ? 3 CYS B CB 1 ATOM 3060 S SG . CYS B 1 3 ? 22.841 -55.452 -45.144 1.00 86.24 ? 3 CYS B SG 1 ATOM 3061 N N . ILE B 1 4 ? 26.488 -53.911 -42.177 1.00 70.90 ? 4 ILE B N 1 ATOM 3062 C CA . ILE B 1 4 ? 27.334 -53.857 -40.995 1.00 69.07 ? 4 ILE B CA 1 ATOM 3063 C C . ILE B 1 4 ? 27.172 -52.459 -40.353 1.00 73.77 ? 4 ILE B C 1 ATOM 3064 O O . ILE B 1 4 ? 27.627 -51.454 -40.912 1.00 72.71 ? 4 ILE B O 1 ATOM 3065 C CB . ILE B 1 4 ? 28.807 -54.202 -41.340 1.00 71.20 ? 4 ILE B CB 1 ATOM 3066 C CG1 . ILE B 1 4 ? 28.920 -55.527 -42.111 1.00 70.75 ? 4 ILE B CG1 1 ATOM 3067 C CG2 . ILE B 1 4 ? 29.692 -54.190 -40.085 1.00 70.62 ? 4 ILE B CG2 1 ATOM 3068 C CD1 . ILE B 1 4 ? 30.254 -55.678 -42.890 1.00 77.76 ? 4 ILE B CD1 1 ATOM 3069 N N . GLY B 1 5 ? 26.478 -52.418 -39.217 1.00 71.94 ? 5 GLY B N 1 ATOM 3070 C CA . GLY B 1 5 ? 26.204 -51.181 -38.484 1.00 72.07 ? 5 GLY B CA 1 ATOM 3071 C C . GLY B 1 5 ? 24.726 -50.900 -38.278 1.00 75.99 ? 5 GLY B C 1 ATOM 3072 O O . GLY B 1 5 ? 24.361 -50.225 -37.309 1.00 76.67 ? 5 GLY B O 1 ATOM 3073 N N . ILE B 1 6 ? 23.877 -51.431 -39.201 1.00 70.76 ? 6 ILE B N 1 ATOM 3074 C CA . ILE B 1 6 ? 22.418 -51.331 -39.246 1.00 70.33 ? 6 ILE B CA 1 ATOM 3075 C C . ILE B 1 6 ? 21.820 -52.355 -38.272 1.00 78.44 ? 6 ILE B C 1 ATOM 3076 O O . ILE B 1 6 ? 22.044 -53.563 -38.425 1.00 80.46 ? 6 ILE B O 1 ATOM 3077 C CB . ILE B 1 6 ? 21.862 -51.497 -40.715 1.00 72.20 ? 6 ILE B CB 1 ATOM 3078 C CG1 . ILE B 1 6 ? 22.209 -50.271 -41.588 1.00 71.90 ? 6 ILE B CG1 1 ATOM 3079 C CG2 . ILE B 1 6 ? 20.344 -51.795 -40.765 1.00 71.83 ? 6 ILE B CG2 1 ATOM 3080 C CD1 . ILE B 1 6 ? 22.062 -50.473 -43.092 1.00 75.61 ? 6 ILE B CD1 1 ATOM 3081 N N . SER B 1 7 ? 21.023 -51.862 -37.301 1.00 74.13 ? 7 SER B N 1 ATOM 3082 C CA . SER B 1 7 ? 20.357 -52.681 -36.298 1.00 72.68 ? 7 SER B CA 1 ATOM 3083 C C . SER B 1 7 ? 19.216 -53.516 -36.879 1.00 73.52 ? 7 SER B C 1 ATOM 3084 O O . SER B 1 7 ? 19.070 -54.664 -36.484 1.00 73.35 ? 7 SER B O 1 ATOM 3085 C CB . SER B 1 7 ? 19.872 -51.813 -35.148 1.00 76.14 ? 7 SER B CB 1 ATOM 3086 O OG . SER B 1 7 ? 19.014 -50.807 -35.653 1.00 85.92 ? 7 SER B OG 1 ATOM 3087 N N . ASN B 1 8 ? 18.408 -52.972 -37.797 1.00 69.18 ? 8 ASN B N 1 ATOM 3088 C CA . ASN B 1 8 ? 17.321 -53.780 -38.360 1.00 69.26 ? 8 ASN B CA 1 ATOM 3089 C C . ASN B 1 8 ? 17.829 -54.584 -39.545 1.00 73.84 ? 8 ASN B C 1 ATOM 3090 O O . ASN B 1 8 ? 17.571 -54.259 -40.701 1.00 73.18 ? 8 ASN B O 1 ATOM 3091 C CB . ASN B 1 8 ? 16.068 -52.953 -38.686 1.00 71.46 ? 8 ASN B CB 1 ATOM 3092 C CG . ASN B 1 8 ? 14.888 -53.806 -39.118 1.00 95.78 ? 8 ASN B CG 1 ATOM 3093 O OD1 . ASN B 1 8 ? 14.722 -54.969 -38.694 1.00 95.46 ? 8 ASN B OD1 1 ATOM 3094 N ND2 . ASN B 1 8 ? 14.052 -53.253 -39.987 1.00 80.86 ? 8 ASN B ND2 1 ATOM 3095 N N . ARG B 1 9 ? 18.571 -55.649 -39.236 1.00 72.00 ? 9 ARG B N 1 ATOM 3096 C CA . ARG B 1 9 ? 19.256 -56.499 -40.209 1.00 71.46 ? 9 ARG B CA 1 ATOM 3097 C C . ARG B 1 9 ? 18.925 -57.979 -40.066 1.00 74.90 ? 9 ARG B C 1 ATOM 3098 O O . ARG B 1 9 ? 18.900 -58.489 -38.948 1.00 75.58 ? 9 ARG B O 1 ATOM 3099 C CB . ARG B 1 9 ? 20.762 -56.266 -40.051 1.00 68.59 ? 9 ARG B CB 1 ATOM 3100 C CG . ARG B 1 9 ? 21.614 -57.014 -41.032 1.00 75.26 ? 9 ARG B CG 1 ATOM 3101 C CD . ARG B 1 9 ? 22.974 -57.158 -40.428 1.00 70.99 ? 9 ARG B CD 1 ATOM 3102 N NE . ARG B 1 9 ? 23.898 -57.773 -41.363 1.00 54.41 ? 9 ARG B NE 1 ATOM 3103 C CZ . ARG B 1 9 ? 25.203 -57.776 -41.190 1.00 65.85 ? 9 ARG B CZ 1 ATOM 3104 N NH1 . ARG B 1 9 ? 25.731 -57.244 -40.097 1.00 48.12 ? 9 ARG B NH1 1 ATOM 3105 N NH2 . ARG B 1 9 ? 25.994 -58.345 -42.088 1.00 68.27 ? 9 ARG B NH2 1 ATOM 3106 N N . ASP B 1 10 ? 18.710 -58.667 -41.190 1.00 70.73 ? 10 ASP B N 1 ATOM 3107 C CA . ASP B 1 10 ? 18.405 -60.092 -41.209 1.00 71.75 ? 10 ASP B CA 1 ATOM 3108 C C . ASP B 1 10 ? 19.504 -60.882 -41.918 1.00 78.42 ? 10 ASP B C 1 ATOM 3109 O O . ASP B 1 10 ? 20.074 -60.397 -42.904 1.00 79.78 ? 10 ASP B O 1 ATOM 3110 C CB . ASP B 1 10 ? 17.053 -60.355 -41.880 1.00 74.12 ? 10 ASP B CB 1 ATOM 3111 C CG . ASP B 1 10 ? 15.887 -59.531 -41.355 1.00 99.16 ? 10 ASP B CG 1 ATOM 3112 O OD1 . ASP B 1 10 ? 15.724 -59.444 -40.112 1.00 101.91 ? 10 ASP B OD1 1 ATOM 3113 O OD2 . ASP B 1 10 ? 15.098 -59.026 -42.183 1.00 113.20 ? 10 ASP B OD2 1 ATOM 3114 N N . PHE B 1 11 ? 19.785 -62.109 -41.421 1.00 73.31 ? 11 PHE B N 1 ATOM 3115 C CA . PHE B 1 11 ? 20.790 -63.000 -41.996 1.00 72.20 ? 11 PHE B CA 1 ATOM 3116 C C . PHE B 1 11 ? 20.070 -64.179 -42.615 1.00 79.99 ? 11 PHE B C 1 ATOM 3117 O O . PHE B 1 11 ? 19.833 -65.187 -41.953 1.00 79.83 ? 11 PHE B O 1 ATOM 3118 C CB . PHE B 1 11 ? 21.801 -63.455 -40.949 1.00 72.85 ? 11 PHE B CB 1 ATOM 3119 C CG . PHE B 1 11 ? 22.596 -62.344 -40.323 1.00 73.66 ? 11 PHE B CG 1 ATOM 3120 C CD1 . PHE B 1 11 ? 22.044 -61.546 -39.320 1.00 75.12 ? 11 PHE B CD1 1 ATOM 3121 C CD2 . PHE B 1 11 ? 23.905 -62.105 -40.714 1.00 76.23 ? 11 PHE B CD2 1 ATOM 3122 C CE1 . PHE B 1 11 ? 22.778 -60.509 -38.739 1.00 77.95 ? 11 PHE B CE1 1 ATOM 3123 C CE2 . PHE B 1 11 ? 24.646 -61.084 -40.122 1.00 77.32 ? 11 PHE B CE2 1 ATOM 3124 C CZ . PHE B 1 11 ? 24.079 -60.295 -39.129 1.00 76.46 ? 11 PHE B CZ 1 ATOM 3125 N N . VAL B 1 12 ? 19.690 -64.032 -43.889 1.00 79.52 ? 12 VAL B N 1 ATOM 3126 C CA . VAL B 1 12 ? 18.988 -65.055 -44.666 1.00 79.71 ? 12 VAL B CA 1 ATOM 3127 C C . VAL B 1 12 ? 19.989 -66.044 -45.302 1.00 82.15 ? 12 VAL B C 1 ATOM 3128 O O . VAL B 1 12 ? 20.806 -65.638 -46.120 1.00 79.92 ? 12 VAL B O 1 ATOM 3129 C CB . VAL B 1 12 ? 18.063 -64.406 -45.740 1.00 84.05 ? 12 VAL B CB 1 ATOM 3130 C CG1 . VAL B 1 12 ? 17.356 -65.468 -46.576 1.00 83.74 ? 12 VAL B CG1 1 ATOM 3131 C CG2 . VAL B 1 12 ? 17.049 -63.454 -45.112 1.00 83.81 ? 12 VAL B CG2 1 ATOM 3132 N N . GLU B 1 13 ? 19.901 -67.328 -44.941 1.00 80.67 ? 13 GLU B N 1 ATOM 3133 C CA . GLU B 1 13 ? 20.750 -68.353 -45.539 1.00 81.48 ? 13 GLU B CA 1 ATOM 3134 C C . GLU B 1 13 ? 19.911 -69.320 -46.371 1.00 85.95 ? 13 GLU B C 1 ATOM 3135 O O . GLU B 1 13 ? 18.909 -69.866 -45.900 1.00 84.83 ? 13 GLU B O 1 ATOM 3136 C CB . GLU B 1 13 ? 21.608 -69.089 -44.495 1.00 83.12 ? 13 GLU B CB 1 ATOM 3137 C CG . GLU B 1 13 ? 22.742 -69.899 -45.119 1.00 97.00 ? 13 GLU B CG 1 ATOM 3138 C CD . GLU B 1 13 ? 23.663 -70.667 -44.184 1.00 129.59 ? 13 GLU B CD 1 ATOM 3139 O OE1 . GLU B 1 13 ? 23.200 -71.106 -43.104 1.00 127.57 ? 13 GLU B OE1 1 ATOM 3140 O OE2 . GLU B 1 13 ? 24.839 -70.883 -44.564 1.00 124.43 ? 13 GLU B OE2 1 ATOM 3141 N N . GLY B 1 14 ? 20.320 -69.494 -47.613 1.00 83.65 ? 14 GLY B N 1 ATOM 3142 C CA . GLY B 1 14 ? 19.651 -70.408 -48.527 1.00 117.91 ? 14 GLY B CA 1 ATOM 3143 C C . GLY B 1 14 ? 20.189 -71.815 -48.384 1.00 132.13 ? 14 GLY B C 1 ATOM 3144 O O . GLY B 1 14 ? 21.399 -72.006 -48.243 1.00 90.86 ? 14 GLY B O 1 ATOM 3145 N N . TRP B 1 20 ? 17.467 -70.525 -55.266 1.00 127.34 ? 20 TRP B N 1 ATOM 3146 C CA . TRP B 1 20 ? 16.177 -69.919 -54.941 1.00 127.51 ? 20 TRP B CA 1 ATOM 3147 C C . TRP B 1 20 ? 16.019 -69.656 -53.416 1.00 126.05 ? 20 TRP B C 1 ATOM 3148 O O . TRP B 1 20 ? 15.744 -70.570 -52.633 1.00 124.53 ? 20 TRP B O 1 ATOM 3149 C CB . TRP B 1 20 ? 14.986 -70.701 -55.555 1.00 127.77 ? 20 TRP B CB 1 ATOM 3150 C CG . TRP B 1 20 ? 14.729 -72.075 -54.997 1.00 129.93 ? 20 TRP B CG 1 ATOM 3151 C CD1 . TRP B 1 20 ? 13.645 -72.472 -54.267 1.00 132.99 ? 20 TRP B CD1 1 ATOM 3152 C CD2 . TRP B 1 20 ? 15.566 -73.238 -55.140 1.00 130.32 ? 20 TRP B CD2 1 ATOM 3153 N NE1 . TRP B 1 20 ? 13.755 -73.805 -53.939 1.00 132.82 ? 20 TRP B NE1 1 ATOM 3154 C CE2 . TRP B 1 20 ? 14.929 -74.299 -54.455 1.00 134.61 ? 20 TRP B CE2 1 ATOM 3155 C CE3 . TRP B 1 20 ? 16.800 -73.486 -55.777 1.00 131.81 ? 20 TRP B CE3 1 ATOM 3156 C CZ2 . TRP B 1 20 ? 15.486 -75.587 -54.385 1.00 134.19 ? 20 TRP B CZ2 1 ATOM 3157 C CZ3 . TRP B 1 20 ? 17.357 -74.756 -55.694 1.00 133.46 ? 20 TRP B CZ3 1 ATOM 3158 C CH2 . TRP B 1 20 ? 16.701 -75.792 -55.013 1.00 134.18 ? 20 TRP B CH2 1 ATOM 3159 N N . VAL B 1 21 ? 16.244 -68.378 -53.014 1.00 119.69 ? 21 VAL B N 1 ATOM 3160 C CA . VAL B 1 21 ? 16.156 -67.870 -51.631 1.00 117.48 ? 21 VAL B CA 1 ATOM 3161 C C . VAL B 1 21 ? 15.181 -66.663 -51.559 1.00 118.06 ? 21 VAL B C 1 ATOM 3162 O O . VAL B 1 21 ? 15.261 -65.747 -52.384 1.00 118.33 ? 21 VAL B O 1 ATOM 3163 C CB . VAL B 1 21 ? 17.551 -67.597 -50.980 1.00 120.20 ? 21 VAL B CB 1 ATOM 3164 C CG1 . VAL B 1 21 ? 18.274 -66.407 -51.607 1.00 119.51 ? 21 VAL B CG1 1 ATOM 3165 C CG2 . VAL B 1 21 ? 17.440 -67.437 -49.474 1.00 119.86 ? 21 VAL B CG2 1 ATOM 3166 N N . ASP B 1 22 ? 14.247 -66.690 -50.597 1.00 110.48 ? 22 ASP B N 1 ATOM 3167 C CA . ASP B 1 22 ? 13.247 -65.643 -50.459 1.00 108.44 ? 22 ASP B CA 1 ATOM 3168 C C . ASP B 1 22 ? 13.601 -64.595 -49.435 1.00 106.74 ? 22 ASP B C 1 ATOM 3169 O O . ASP B 1 22 ? 13.829 -64.923 -48.267 1.00 105.66 ? 22 ASP B O 1 ATOM 3170 C CB . ASP B 1 22 ? 11.868 -66.247 -50.181 1.00 110.72 ? 22 ASP B CB 1 ATOM 3171 C CG . ASP B 1 22 ? 11.177 -66.755 -51.426 1.00 123.89 ? 22 ASP B CG 1 ATOM 3172 O OD1 . ASP B 1 22 ? 10.965 -65.949 -52.358 1.00 123.94 ? 22 ASP B OD1 1 ATOM 3173 O OD2 . ASP B 1 22 ? 10.812 -67.949 -51.455 1.00 133.63 ? 22 ASP B OD2 1 ATOM 3174 N N . ILE B 1 23 ? 13.642 -63.322 -49.878 1.00 99.97 ? 23 ILE B N 1 ATOM 3175 C CA . ILE B 1 23 ? 13.939 -62.179 -49.002 1.00 98.48 ? 23 ILE B CA 1 ATOM 3176 C C . ILE B 1 23 ? 12.858 -61.108 -49.065 1.00 100.71 ? 23 ILE B C 1 ATOM 3177 O O . ILE B 1 23 ? 12.173 -60.972 -50.081 1.00 100.03 ? 23 ILE B O 1 ATOM 3178 C CB . ILE B 1 23 ? 15.350 -61.565 -49.180 1.00 101.16 ? 23 ILE B CB 1 ATOM 3179 C CG1 . ILE B 1 23 ? 15.570 -61.019 -50.608 1.00 101.26 ? 23 ILE B CG1 1 ATOM 3180 C CG2 . ILE B 1 23 ? 16.429 -62.548 -48.759 1.00 101.76 ? 23 ILE B CG2 1 ATOM 3181 C CD1 . ILE B 1 23 ? 16.586 -59.882 -50.696 1.00 104.93 ? 23 ILE B CD1 1 ATOM 3182 N N . VAL B 1 24 ? 12.718 -60.357 -47.958 1.00 96.83 ? 24 VAL B N 1 ATOM 3183 C CA . VAL B 1 24 ? 11.747 -59.281 -47.799 1.00 96.35 ? 24 VAL B CA 1 ATOM 3184 C C . VAL B 1 24 ? 12.505 -57.985 -47.567 1.00 98.36 ? 24 VAL B C 1 ATOM 3185 O O . VAL B 1 24 ? 13.069 -57.765 -46.489 1.00 97.47 ? 24 VAL B O 1 ATOM 3186 C CB . VAL B 1 24 ? 10.698 -59.548 -46.677 1.00 100.41 ? 24 VAL B CB 1 ATOM 3187 C CG1 . VAL B 1 24 ? 9.604 -58.489 -46.680 1.00 100.14 ? 24 VAL B CG1 1 ATOM 3188 C CG2 . VAL B 1 24 ? 10.074 -60.933 -46.816 1.00 100.39 ? 24 VAL B CG2 1 ATOM 3189 N N . LEU B 1 25 ? 12.519 -57.131 -48.583 1.00 93.18 ? 25 LEU B N 1 ATOM 3190 C CA . LEU B 1 25 ? 13.164 -55.844 -48.447 1.00 91.73 ? 25 LEU B CA 1 ATOM 3191 C C . LEU B 1 25 ? 12.147 -54.765 -48.057 1.00 92.68 ? 25 LEU B C 1 ATOM 3192 O O . LEU B 1 25 ? 11.025 -54.752 -48.560 1.00 91.59 ? 25 LEU B O 1 ATOM 3193 C CB . LEU B 1 25 ? 13.925 -55.471 -49.723 1.00 91.58 ? 25 LEU B CB 1 ATOM 3194 C CG . LEU B 1 25 ? 15.099 -56.374 -50.115 1.00 96.12 ? 25 LEU B CG 1 ATOM 3195 C CD1 . LEU B 1 25 ? 15.798 -55.839 -51.339 1.00 96.58 ? 25 LEU B CD1 1 ATOM 3196 C CD2 . LEU B 1 25 ? 16.109 -56.523 -48.984 1.00 98.11 ? 25 LEU B CD2 1 ATOM 3197 N N . GLU B 1 26 ? 12.532 -53.896 -47.121 1.00 87.71 ? 26 GLU B N 1 ATOM 3198 C CA . GLU B 1 26 ? 11.724 -52.766 -46.679 1.00 86.86 ? 26 GLU B CA 1 ATOM 3199 C C . GLU B 1 26 ? 12.632 -51.588 -46.291 1.00 91.36 ? 26 GLU B C 1 ATOM 3200 O O . GLU B 1 26 ? 13.863 -51.725 -46.298 1.00 91.01 ? 26 GLU B O 1 ATOM 3201 C CB . GLU B 1 26 ? 10.691 -53.152 -45.604 1.00 87.97 ? 26 GLU B CB 1 ATOM 3202 C CG . GLU B 1 26 ? 11.251 -53.474 -44.231 1.00 98.07 ? 26 GLU B CG 1 ATOM 3203 C CD . GLU B 1 26 ? 10.214 -53.850 -43.189 1.00 111.99 ? 26 GLU B CD 1 ATOM 3204 O OE1 . GLU B 1 26 ? 9.289 -53.041 -42.945 1.00 104.01 ? 26 GLU B OE1 1 ATOM 3205 O OE2 . GLU B 1 26 ? 10.346 -54.944 -42.593 1.00 96.63 ? 26 GLU B OE2 1 ATOM 3206 N N . HIS B 1 27 ? 12.029 -50.417 -46.048 1.00 88.19 ? 27 HIS B N 1 ATOM 3207 C CA . HIS B 1 27 ? 12.781 -49.214 -45.733 1.00 88.16 ? 27 HIS B CA 1 ATOM 3208 C C . HIS B 1 27 ? 13.263 -49.259 -44.314 1.00 92.28 ? 27 HIS B C 1 ATOM 3209 O O . HIS B 1 27 ? 12.524 -49.687 -43.435 1.00 92.57 ? 27 HIS B O 1 ATOM 3210 C CB . HIS B 1 27 ? 11.969 -47.942 -46.044 1.00 88.99 ? 27 HIS B CB 1 ATOM 3211 C CG . HIS B 1 27 ? 11.992 -47.552 -47.498 1.00 92.47 ? 27 HIS B CG 1 ATOM 3212 N ND1 . HIS B 1 27 ? 12.907 -46.628 -47.990 1.00 94.22 ? 27 HIS B ND1 1 ATOM 3213 C CD2 . HIS B 1 27 ? 11.229 -47.993 -48.527 1.00 94.20 ? 27 HIS B CD2 1 ATOM 3214 C CE1 . HIS B 1 27 ? 12.663 -46.530 -49.290 1.00 93.55 ? 27 HIS B CE1 1 ATOM 3215 N NE2 . HIS B 1 27 ? 11.665 -47.331 -49.660 1.00 93.95 ? 27 HIS B NE2 1 ATOM 3216 N N . GLY B 1 28 ? 14.522 -48.872 -44.119 1.00 88.58 ? 28 GLY B N 1 ATOM 3217 C CA . GLY B 1 28 ? 15.203 -48.852 -42.822 1.00 87.49 ? 28 GLY B CA 1 ATOM 3218 C C . GLY B 1 28 ? 15.723 -50.208 -42.390 1.00 87.86 ? 28 GLY B C 1 ATOM 3219 O O . GLY B 1 28 ? 16.154 -50.381 -41.248 1.00 86.50 ? 28 GLY B O 1 ATOM 3220 N N . SER B 1 29 ? 15.664 -51.173 -43.315 1.00 83.09 ? 29 SER B N 1 ATOM 3221 C CA . SER B 1 29 ? 16.046 -52.562 -43.140 1.00 82.50 ? 29 SER B CA 1 ATOM 3222 C C . SER B 1 29 ? 17.092 -52.983 -44.173 1.00 86.51 ? 29 SER B C 1 ATOM 3223 O O . SER B 1 29 ? 16.973 -52.644 -45.355 1.00 87.00 ? 29 SER B O 1 ATOM 3224 C CB . SER B 1 29 ? 14.803 -53.452 -43.227 1.00 84.59 ? 29 SER B CB 1 ATOM 3225 O OG . SER B 1 29 ? 15.030 -54.811 -43.580 1.00 88.21 ? 29 SER B OG 1 ATOM 3226 N N . CYS B 1 30 ? 18.092 -53.754 -43.711 1.00 81.68 ? 30 CYS B N 1 ATOM 3227 C CA . CYS B 1 30 ? 19.165 -54.325 -44.512 1.00 80.97 ? 30 CYS B CA 1 ATOM 3228 C C . CYS B 1 30 ? 19.066 -55.844 -44.487 1.00 80.33 ? 30 CYS B C 1 ATOM 3229 O O . CYS B 1 30 ? 18.587 -56.387 -43.499 1.00 80.53 ? 30 CYS B O 1 ATOM 3230 C CB . CYS B 1 30 ? 20.515 -53.849 -43.989 1.00 82.18 ? 30 CYS B CB 1 ATOM 3231 S SG . CYS B 1 30 ? 21.793 -53.708 -45.271 1.00 86.48 ? 30 CYS B SG 1 ATOM 3232 N N . VAL B 1 31 ? 19.510 -56.537 -45.549 1.00 73.62 ? 31 VAL B N 1 ATOM 3233 C CA . VAL B 1 31 ? 19.476 -58.010 -45.587 1.00 72.62 ? 31 VAL B CA 1 ATOM 3234 C C . VAL B 1 31 ? 20.831 -58.621 -46.023 1.00 78.17 ? 31 VAL B C 1 ATOM 3235 O O . VAL B 1 31 ? 21.406 -58.189 -47.017 1.00 77.89 ? 31 VAL B O 1 ATOM 3236 C CB . VAL B 1 31 ? 18.291 -58.538 -46.431 1.00 74.59 ? 31 VAL B CB 1 ATOM 3237 C CG1 . VAL B 1 31 ? 18.450 -60.014 -46.772 1.00 73.99 ? 31 VAL B CG1 1 ATOM 3238 C CG2 . VAL B 1 31 ? 16.976 -58.289 -45.721 1.00 74.04 ? 31 VAL B CG2 1 ATOM 3239 N N . THR B 1 32 ? 21.318 -59.636 -45.291 1.00 75.63 ? 32 THR B N 1 ATOM 3240 C CA . THR B 1 32 ? 22.562 -60.331 -45.619 1.00 76.34 ? 32 THR B CA 1 ATOM 3241 C C . THR B 1 32 ? 22.230 -61.768 -46.053 1.00 84.12 ? 32 THR B C 1 ATOM 3242 O O . THR B 1 32 ? 21.633 -62.520 -45.287 1.00 83.62 ? 32 THR B O 1 ATOM 3243 C CB . THR B 1 32 ? 23.567 -60.208 -44.463 1.00 78.62 ? 32 THR B CB 1 ATOM 3244 O OG1 . THR B 1 32 ? 23.878 -58.829 -44.251 1.00 76.46 ? 32 THR B OG1 1 ATOM 3245 C CG2 . THR B 1 32 ? 24.842 -60.964 -44.719 1.00 74.43 ? 32 THR B CG2 1 ATOM 3246 N N . THR B 1 33 ? 22.586 -62.128 -47.296 1.00 84.13 ? 33 THR B N 1 ATOM 3247 C CA . THR B 1 33 ? 22.294 -63.449 -47.869 1.00 85.39 ? 33 THR B CA 1 ATOM 3248 C C . THR B 1 33 ? 23.542 -64.279 -48.129 1.00 92.40 ? 33 THR B C 1 ATOM 3249 O O . THR B 1 33 ? 24.512 -63.803 -48.730 1.00 92.68 ? 33 THR B O 1 ATOM 3250 C CB . THR B 1 33 ? 21.480 -63.335 -49.141 1.00 94.26 ? 33 THR B CB 1 ATOM 3251 O OG1 . THR B 1 33 ? 22.244 -62.587 -50.097 1.00 102.05 ? 33 THR B OG1 1 ATOM 3252 C CG2 . THR B 1 33 ? 20.125 -62.711 -48.906 1.00 88.73 ? 33 THR B CG2 1 ATOM 3253 N N . MET B 1 34 ? 23.481 -65.543 -47.700 1.00 89.94 ? 34 MET B N 1 ATOM 3254 C CA . MET B 1 34 ? 24.557 -66.515 -47.798 1.00 90.23 ? 34 MET B CA 1 ATOM 3255 C C . MET B 1 34 ? 24.060 -67.833 -48.359 1.00 97.96 ? 34 MET B C 1 ATOM 3256 O O . MET B 1 34 ? 22.905 -68.216 -48.152 1.00 97.00 ? 34 MET B O 1 ATOM 3257 C CB . MET B 1 34 ? 25.149 -66.775 -46.411 1.00 92.34 ? 34 MET B CB 1 ATOM 3258 C CG . MET B 1 34 ? 25.590 -65.535 -45.703 1.00 96.23 ? 34 MET B CG 1 ATOM 3259 S SD . MET B 1 34 ? 25.743 -65.819 -43.940 1.00 100.90 ? 34 MET B SD 1 ATOM 3260 C CE . MET B 1 34 ? 27.383 -66.582 -43.885 1.00 97.75 ? 34 MET B CE 1 ATOM 3261 N N . ALA B 1 35 ? 24.961 -68.539 -49.055 1.00 98.55 ? 35 ALA B N 1 ATOM 3262 C CA . ALA B 1 35 ? 24.747 -69.871 -49.623 1.00 99.93 ? 35 ALA B CA 1 ATOM 3263 C C . ALA B 1 35 ? 26.116 -70.540 -49.752 1.00 105.39 ? 35 ALA B C 1 ATOM 3264 O O . ALA B 1 35 ? 27.111 -69.826 -49.958 1.00 105.26 ? 35 ALA B O 1 ATOM 3265 C CB . ALA B 1 35 ? 24.082 -69.766 -50.981 1.00 100.78 ? 35 ALA B CB 1 ATOM 3266 N N . LYS B 1 36 ? 26.178 -71.892 -49.609 1.00 101.81 ? 36 LYS B N 1 ATOM 3267 C CA . LYS B 1 36 ? 27.449 -72.618 -49.703 1.00 101.39 ? 36 LYS B CA 1 ATOM 3268 C C . LYS B 1 36 ? 28.091 -72.429 -51.070 1.00 103.77 ? 36 LYS B C 1 ATOM 3269 O O . LYS B 1 36 ? 27.428 -72.641 -52.091 1.00 102.87 ? 36 LYS B O 1 ATOM 3270 C CB . LYS B 1 36 ? 27.323 -74.116 -49.340 1.00 104.05 ? 36 LYS B CB 1 ATOM 3271 C CG . LYS B 1 36 ? 28.684 -74.790 -49.136 1.00 122.15 ? 36 LYS B CG 1 ATOM 3272 C CD . LYS B 1 36 ? 28.582 -76.249 -48.757 1.00 132.60 ? 36 LYS B CD 1 ATOM 3273 C CE . LYS B 1 36 ? 29.954 -76.880 -48.691 1.00 144.51 ? 36 LYS B CE 1 ATOM 3274 N NZ . LYS B 1 36 ? 29.878 -78.265 -48.175 1.00 152.19 ? 36 LYS B NZ 1 ATOM 3275 N N . ASN B 1 37 ? 29.377 -71.978 -51.062 1.00 99.59 ? 37 ASN B N 1 ATOM 3276 C CA . ASN B 1 37 ? 30.236 -71.707 -52.225 1.00 99.35 ? 37 ASN B CA 1 ATOM 3277 C C . ASN B 1 37 ? 29.648 -70.636 -53.176 1.00 101.00 ? 37 ASN B C 1 ATOM 3278 O O . ASN B 1 37 ? 29.863 -70.658 -54.393 1.00 99.97 ? 37 ASN B O 1 ATOM 3279 C CB . ASN B 1 37 ? 30.629 -72.999 -52.959 1.00 102.29 ? 37 ASN B CB 1 ATOM 3280 C CG . ASN B 1 37 ? 31.445 -73.906 -52.069 1.00 130.05 ? 37 ASN B CG 1 ATOM 3281 O OD1 . ASN B 1 37 ? 30.989 -74.979 -51.661 1.00 121.41 ? 37 ASN B OD1 1 ATOM 3282 N ND2 . ASN B 1 37 ? 32.639 -73.451 -51.679 1.00 124.26 ? 37 ASN B ND2 1 ATOM 3283 N N . LYS B 1 38 ? 28.927 -69.682 -52.586 1.00 96.20 ? 38 LYS B N 1 ATOM 3284 C CA . LYS B 1 38 ? 28.332 -68.548 -53.278 1.00 95.05 ? 38 LYS B CA 1 ATOM 3285 C C . LYS B 1 38 ? 28.695 -67.308 -52.476 1.00 96.82 ? 38 LYS B C 1 ATOM 3286 O O . LYS B 1 38 ? 28.873 -67.409 -51.256 1.00 97.03 ? 38 LYS B O 1 ATOM 3287 C CB . LYS B 1 38 ? 26.804 -68.692 -53.422 1.00 97.46 ? 38 LYS B CB 1 ATOM 3288 C CG . LYS B 1 38 ? 26.334 -69.896 -54.251 1.00 112.99 ? 38 LYS B CG 1 ATOM 3289 C CD . LYS B 1 38 ? 26.521 -69.733 -55.751 1.00 122.53 ? 38 LYS B CD 1 ATOM 3290 C CE . LYS B 1 38 ? 25.988 -70.937 -56.487 1.00 129.06 ? 38 LYS B CE 1 ATOM 3291 N NZ . LYS B 1 38 ? 26.057 -70.748 -57.956 1.00 133.89 ? 38 LYS B NZ 1 ATOM 3292 N N . PRO B 1 39 ? 28.852 -66.137 -53.124 1.00 90.45 ? 39 PRO B N 1 ATOM 3293 C CA . PRO B 1 39 ? 29.250 -64.939 -52.370 1.00 89.29 ? 39 PRO B CA 1 ATOM 3294 C C . PRO B 1 39 ? 28.156 -64.378 -51.469 1.00 93.19 ? 39 PRO B C 1 ATOM 3295 O O . PRO B 1 39 ? 26.960 -64.439 -51.793 1.00 92.96 ? 39 PRO B O 1 ATOM 3296 C CB . PRO B 1 39 ? 29.671 -63.943 -53.453 1.00 90.60 ? 39 PRO B CB 1 ATOM 3297 C CG . PRO B 1 39 ? 29.555 -64.671 -54.745 1.00 95.25 ? 39 PRO B CG 1 ATOM 3298 C CD . PRO B 1 39 ? 28.679 -65.838 -54.554 1.00 91.15 ? 39 PRO B CD 1 ATOM 3299 N N . THR B 1 40 ? 28.577 -63.831 -50.322 1.00 88.68 ? 40 THR B N 1 ATOM 3300 C CA . THR B 1 40 ? 27.664 -63.202 -49.376 1.00 87.59 ? 40 THR B CA 1 ATOM 3301 C C . THR B 1 40 ? 27.276 -61.814 -49.914 1.00 89.45 ? 40 THR B C 1 ATOM 3302 O O . THR B 1 40 ? 28.153 -61.029 -50.308 1.00 87.80 ? 40 THR B O 1 ATOM 3303 C CB . THR B 1 40 ? 28.248 -63.246 -47.969 1.00 86.47 ? 40 THR B CB 1 ATOM 3304 O OG1 . THR B 1 40 ? 28.334 -64.624 -47.581 1.00 78.56 ? 40 THR B OG1 1 ATOM 3305 C CG2 . THR B 1 40 ? 27.411 -62.478 -46.961 1.00 81.05 ? 40 THR B CG2 1 ATOM 3306 N N . LEU B 1 41 ? 25.951 -61.549 -49.983 1.00 83.86 ? 41 LEU B N 1 ATOM 3307 C CA . LEU B 1 41 ? 25.417 -60.291 -50.506 1.00 81.29 ? 41 LEU B CA 1 ATOM 3308 C C . LEU B 1 41 ? 24.585 -59.505 -49.511 1.00 81.48 ? 41 LEU B C 1 ATOM 3309 O O . LEU B 1 41 ? 23.846 -60.080 -48.707 1.00 79.73 ? 41 LEU B O 1 ATOM 3310 C CB . LEU B 1 41 ? 24.584 -60.528 -51.771 1.00 80.41 ? 41 LEU B CB 1 ATOM 3311 C CG . LEU B 1 41 ? 25.269 -61.121 -52.987 1.00 83.41 ? 41 LEU B CG 1 ATOM 3312 C CD1 . LEU B 1 41 ? 24.252 -61.480 -54.005 1.00 82.99 ? 41 LEU B CD1 1 ATOM 3313 C CD2 . LEU B 1 41 ? 26.250 -60.164 -53.597 1.00 83.70 ? 41 LEU B CD2 1 ATOM 3314 N N . ASP B 1 42 ? 24.673 -58.171 -49.634 1.00 77.15 ? 42 ASP B N 1 ATOM 3315 C CA . ASP B 1 42 ? 23.948 -57.184 -48.830 1.00 76.15 ? 42 ASP B CA 1 ATOM 3316 C C . ASP B 1 42 ? 22.901 -56.449 -49.670 1.00 77.85 ? 42 ASP B C 1 ATOM 3317 O O . ASP B 1 42 ? 23.231 -55.891 -50.707 1.00 77.85 ? 42 ASP B O 1 ATOM 3318 C CB . ASP B 1 42 ? 24.928 -56.208 -48.144 1.00 77.71 ? 42 ASP B CB 1 ATOM 3319 C CG . ASP B 1 42 ? 25.515 -56.719 -46.842 1.00 88.72 ? 42 ASP B CG 1 ATOM 3320 O OD1 . ASP B 1 42 ? 25.468 -57.952 -46.605 1.00 90.96 ? 42 ASP B OD1 1 ATOM 3321 O OD2 . ASP B 1 42 ? 25.966 -55.887 -46.035 1.00 92.56 ? 42 ASP B OD2 1 ATOM 3322 N N . PHE B 1 43 ? 21.648 -56.462 -49.228 1.00 73.31 ? 43 PHE B N 1 ATOM 3323 C CA . PHE B 1 43 ? 20.536 -55.813 -49.930 1.00 72.84 ? 43 PHE B CA 1 ATOM 3324 C C . PHE B 1 43 ? 19.838 -54.745 -49.084 1.00 75.88 ? 43 PHE B C 1 ATOM 3325 O O . PHE B 1 43 ? 19.546 -54.971 -47.901 1.00 76.03 ? 43 PHE B O 1 ATOM 3326 C CB . PHE B 1 43 ? 19.489 -56.840 -50.346 1.00 74.48 ? 43 PHE B CB 1 ATOM 3327 C CG . PHE B 1 43 ? 19.983 -57.934 -51.242 1.00 76.63 ? 43 PHE B CG 1 ATOM 3328 C CD1 . PHE B 1 43 ? 20.519 -59.094 -50.714 1.00 80.30 ? 43 PHE B CD1 1 ATOM 3329 C CD2 . PHE B 1 43 ? 19.839 -57.844 -52.619 1.00 80.23 ? 43 PHE B CD2 1 ATOM 3330 C CE1 . PHE B 1 43 ? 20.952 -60.127 -51.552 1.00 83.70 ? 43 PHE B CE1 1 ATOM 3331 C CE2 . PHE B 1 43 ? 20.248 -58.889 -53.454 1.00 81.57 ? 43 PHE B CE2 1 ATOM 3332 C CZ . PHE B 1 43 ? 20.827 -60.012 -52.918 1.00 81.43 ? 43 PHE B CZ 1 ATOM 3333 N N . GLU B 1 44 ? 19.535 -53.600 -49.715 1.00 70.09 ? 44 GLU B N 1 ATOM 3334 C CA . GLU B 1 44 ? 18.809 -52.478 -49.118 1.00 68.53 ? 44 GLU B CA 1 ATOM 3335 C C . GLU B 1 44 ? 17.820 -51.908 -50.128 1.00 76.92 ? 44 GLU B C 1 ATOM 3336 O O . GLU B 1 44 ? 18.111 -51.872 -51.328 1.00 78.43 ? 44 GLU B O 1 ATOM 3337 C CB . GLU B 1 44 ? 19.760 -51.374 -48.655 1.00 68.64 ? 44 GLU B CB 1 ATOM 3338 C CG . GLU B 1 44 ? 19.164 -50.514 -47.562 1.00 75.71 ? 44 GLU B CG 1 ATOM 3339 C CD . GLU B 1 44 ? 20.046 -49.438 -46.952 1.00 102.95 ? 44 GLU B CD 1 ATOM 3340 O OE1 . GLU B 1 44 ? 21.244 -49.705 -46.678 1.00 75.27 ? 44 GLU B OE1 1 ATOM 3341 O OE2 . GLU B 1 44 ? 19.497 -48.349 -46.653 1.00 107.11 ? 44 GLU B OE2 1 ATOM 3342 N N . LEU B 1 45 ? 16.643 -51.475 -49.648 1.00 74.22 ? 45 LEU B N 1 ATOM 3343 C CA . LEU B 1 45 ? 15.659 -50.783 -50.470 1.00 73.43 ? 45 LEU B CA 1 ATOM 3344 C C . LEU B 1 45 ? 15.936 -49.315 -50.199 1.00 79.73 ? 45 LEU B C 1 ATOM 3345 O O . LEU B 1 45 ? 15.724 -48.859 -49.077 1.00 80.02 ? 45 LEU B O 1 ATOM 3346 C CB . LEU B 1 45 ? 14.252 -51.163 -50.044 1.00 72.84 ? 45 LEU B CB 1 ATOM 3347 C CG . LEU B 1 45 ? 13.112 -50.562 -50.828 1.00 77.04 ? 45 LEU B CG 1 ATOM 3348 C CD1 . LEU B 1 45 ? 13.298 -50.757 -52.335 1.00 77.33 ? 45 LEU B CD1 1 ATOM 3349 C CD2 . LEU B 1 45 ? 11.809 -51.170 -50.380 1.00 80.05 ? 45 LEU B CD2 1 ATOM 3350 N N . ILE B 1 46 ? 16.519 -48.616 -51.182 1.00 78.54 ? 46 ILE B N 1 ATOM 3351 C CA . ILE B 1 46 ? 16.928 -47.216 -51.088 1.00 79.88 ? 46 ILE B CA 1 ATOM 3352 C C . ILE B 1 46 ? 15.751 -46.242 -51.277 1.00 85.87 ? 46 ILE B C 1 ATOM 3353 O O . ILE B 1 46 ? 15.593 -45.341 -50.452 1.00 84.33 ? 46 ILE B O 1 ATOM 3354 C CB . ILE B 1 46 ? 18.118 -46.950 -52.050 1.00 83.72 ? 46 ILE B CB 1 ATOM 3355 C CG1 . ILE B 1 46 ? 19.425 -47.501 -51.438 1.00 84.89 ? 46 ILE B CG1 1 ATOM 3356 C CG2 . ILE B 1 46 ? 18.278 -45.462 -52.452 1.00 84.99 ? 46 ILE B CG2 1 ATOM 3357 C CD1 . ILE B 1 46 ? 19.829 -47.013 -49.964 1.00 95.71 ? 46 ILE B CD1 1 ATOM 3358 N N . LYS B 1 47 ? 14.944 -46.406 -52.356 1.00 85.00 ? 47 LYS B N 1 ATOM 3359 C CA . LYS B 1 47 ? 13.783 -45.545 -52.608 1.00 85.13 ? 47 LYS B CA 1 ATOM 3360 C C . LYS B 1 47 ? 12.637 -46.250 -53.331 1.00 89.08 ? 47 LYS B C 1 ATOM 3361 O O . LYS B 1 47 ? 12.841 -47.188 -54.103 1.00 87.43 ? 47 LYS B O 1 ATOM 3362 C CB . LYS B 1 47 ? 14.162 -44.227 -53.333 1.00 87.44 ? 47 LYS B CB 1 ATOM 3363 C CG . LYS B 1 47 ? 14.599 -44.368 -54.790 1.00 102.98 ? 47 LYS B CG 1 ATOM 3364 C CD . LYS B 1 47 ? 15.377 -43.158 -55.269 1.00 117.36 ? 47 LYS B CD 1 ATOM 3365 C CE . LYS B 1 47 ? 16.058 -43.379 -56.601 1.00 127.27 ? 47 LYS B CE 1 ATOM 3366 N NZ . LYS B 1 47 ? 17.468 -43.824 -56.436 1.00 131.99 ? 47 LYS B NZ 1 ATOM 3367 N N . THR B 1 48 ? 11.425 -45.768 -53.038 1.00 86.91 ? 48 THR B N 1 ATOM 3368 C CA . THR B 1 48 ? 10.144 -46.146 -53.629 1.00 86.78 ? 48 THR B CA 1 ATOM 3369 C C . THR B 1 48 ? 9.651 -44.819 -54.248 1.00 89.42 ? 48 THR B C 1 ATOM 3370 O O . THR B 1 48 ? 9.787 -43.778 -53.606 1.00 87.96 ? 48 THR B O 1 ATOM 3371 C CB . THR B 1 48 ? 9.196 -46.703 -52.533 1.00 95.58 ? 48 THR B CB 1 ATOM 3372 O OG1 . THR B 1 48 ? 9.846 -47.741 -51.783 1.00 90.81 ? 48 THR B OG1 1 ATOM 3373 C CG2 . THR B 1 48 ? 7.909 -47.231 -53.097 1.00 94.41 ? 48 THR B CG2 1 ATOM 3374 N N . GLU B 1 49 ? 9.173 -44.832 -55.513 1.00 86.91 ? 49 GLU B N 1 ATOM 3375 C CA . GLU B 1 49 ? 8.722 -43.613 -56.221 1.00 87.02 ? 49 GLU B CA 1 ATOM 3376 C C . GLU B 1 49 ? 7.599 -43.822 -57.265 1.00 91.17 ? 49 GLU B C 1 ATOM 3377 O O . GLU B 1 49 ? 7.537 -44.867 -57.931 1.00 90.21 ? 49 GLU B O 1 ATOM 3378 C CB . GLU B 1 49 ? 9.910 -42.877 -56.889 1.00 88.63 ? 49 GLU B CB 1 ATOM 3379 C CG . GLU B 1 49 ? 10.061 -41.427 -56.446 1.00 104.55 ? 49 GLU B CG 1 ATOM 3380 C CD . GLU B 1 49 ? 10.323 -40.358 -57.498 1.00 130.32 ? 49 GLU B CD 1 ATOM 3381 O OE1 . GLU B 1 49 ? 9.973 -40.572 -58.682 1.00 127.81 ? 49 GLU B OE1 1 ATOM 3382 O OE2 . GLU B 1 49 ? 10.837 -39.278 -57.120 1.00 115.42 ? 49 GLU B OE2 1 ATOM 3383 N N . ALA B 1 50 ? 6.728 -42.787 -57.419 1.00 87.77 ? 50 ALA B N 1 ATOM 3384 C CA . ALA B 1 50 ? 5.655 -42.778 -58.429 1.00 86.69 ? 50 ALA B CA 1 ATOM 3385 C C . ALA B 1 50 ? 6.178 -42.048 -59.677 1.00 88.60 ? 50 ALA B C 1 ATOM 3386 O O . ALA B 1 50 ? 6.678 -40.921 -59.573 1.00 86.99 ? 50 ALA B O 1 ATOM 3387 C CB . ALA B 1 50 ? 4.404 -42.091 -57.894 1.00 87.07 ? 50 ALA B CB 1 ATOM 3388 N N . LYS B 1 51 ? 6.132 -42.726 -60.833 1.00 85.05 ? 51 LYS B N 1 ATOM 3389 C CA . LYS B 1 51 ? 6.622 -42.144 -62.080 1.00 85.10 ? 51 LYS B CA 1 ATOM 3390 C C . LYS B 1 51 ? 5.555 -41.292 -62.759 1.00 87.44 ? 51 LYS B C 1 ATOM 3391 O O . LYS B 1 51 ? 4.557 -41.813 -63.277 1.00 85.55 ? 51 LYS B O 1 ATOM 3392 C CB . LYS B 1 51 ? 7.237 -43.198 -63.027 1.00 88.07 ? 51 LYS B CB 1 ATOM 3393 C CG . LYS B 1 51 ? 8.704 -43.506 -62.705 1.00 99.21 ? 51 LYS B CG 1 ATOM 3394 C CD . LYS B 1 51 ? 9.371 -44.431 -63.717 1.00 108.71 ? 51 LYS B CD 1 ATOM 3395 C CE . LYS B 1 51 ? 9.054 -45.898 -63.509 1.00 120.61 ? 51 LYS B CE 1 ATOM 3396 N NZ . LYS B 1 51 ? 9.897 -46.778 -64.368 1.00 126.35 ? 51 LYS B NZ 1 ATOM 3397 N N . GLN B 1 52 ? 5.782 -39.958 -62.699 1.00 83.81 ? 52 GLN B N 1 ATOM 3398 C CA . GLN B 1 52 ? 4.968 -38.850 -63.247 1.00 83.23 ? 52 GLN B CA 1 ATOM 3399 C C . GLN B 1 52 ? 3.420 -39.040 -62.995 1.00 82.87 ? 52 GLN B C 1 ATOM 3400 O O . GLN B 1 52 ? 2.673 -39.403 -63.919 1.00 82.27 ? 52 GLN B O 1 ATOM 3401 C CB . GLN B 1 52 ? 5.317 -38.592 -64.733 1.00 85.20 ? 52 GLN B CB 1 ATOM 3402 C CG . GLN B 1 52 ? 5.579 -37.108 -65.049 1.00 111.35 ? 52 GLN B CG 1 ATOM 3403 C CD . GLN B 1 52 ? 6.593 -36.809 -66.163 1.00 128.51 ? 52 GLN B CD 1 ATOM 3404 O OE1 . GLN B 1 52 ? 6.627 -37.436 -67.241 1.00 123.96 ? 52 GLN B OE1 1 ATOM 3405 N NE2 . GLN B 1 52 ? 7.405 -35.779 -65.949 1.00 114.66 ? 52 GLN B NE2 1 ATOM 3406 N N . PRO B 1 53 ? 2.936 -38.830 -61.735 1.00 75.21 ? 53 PRO B N 1 ATOM 3407 C CA . PRO B 1 53 ? 1.503 -39.001 -61.454 1.00 73.44 ? 53 PRO B CA 1 ATOM 3408 C C . PRO B 1 53 ? 0.684 -37.752 -61.785 1.00 75.04 ? 53 PRO B C 1 ATOM 3409 O O . PRO B 1 53 ? 1.150 -36.617 -61.624 1.00 74.89 ? 53 PRO B O 1 ATOM 3410 C CB . PRO B 1 53 ? 1.476 -39.319 -59.963 1.00 75.09 ? 53 PRO B CB 1 ATOM 3411 C CG . PRO B 1 53 ? 2.728 -38.737 -59.414 1.00 79.89 ? 53 PRO B CG 1 ATOM 3412 C CD . PRO B 1 53 ? 3.655 -38.378 -60.528 1.00 75.97 ? 53 PRO B CD 1 ATOM 3413 N N . ALA B 1 54 ? -0.550 -37.965 -62.244 1.00 68.80 ? 54 ALA B N 1 ATOM 3414 C CA . ALA B 1 54 ? -1.430 -36.872 -62.635 1.00 66.66 ? 54 ALA B CA 1 ATOM 3415 C C . ALA B 1 54 ? -2.057 -36.178 -61.449 1.00 66.02 ? 54 ALA B C 1 ATOM 3416 O O . ALA B 1 54 ? -2.846 -36.782 -60.714 1.00 66.37 ? 54 ALA B O 1 ATOM 3417 C CB . ALA B 1 54 ? -2.510 -37.368 -63.589 1.00 67.31 ? 54 ALA B CB 1 ATOM 3418 N N . THR B 1 55 ? -1.697 -34.908 -61.262 1.00 58.20 ? 55 THR B N 1 ATOM 3419 C CA . THR B 1 55 ? -2.293 -34.119 -60.203 1.00 56.33 ? 55 THR B CA 1 ATOM 3420 C C . THR B 1 55 ? -3.772 -34.069 -60.459 1.00 55.50 ? 55 THR B C 1 ATOM 3421 O O . THR B 1 55 ? -4.183 -33.715 -61.550 1.00 54.03 ? 55 THR B O 1 ATOM 3422 C CB . THR B 1 55 ? -1.691 -32.734 -60.112 1.00 66.37 ? 55 THR B CB 1 ATOM 3423 O OG1 . THR B 1 55 ? -0.277 -32.811 -60.377 1.00 68.11 ? 55 THR B OG1 1 ATOM 3424 C CG2 . THR B 1 55 ? -1.997 -32.075 -58.765 1.00 61.81 ? 55 THR B CG2 1 ATOM 3425 N N . LEU B 1 56 ? -4.552 -34.588 -59.519 1.00 50.87 ? 56 LEU B N 1 ATOM 3426 C CA . LEU B 1 56 ? -6.001 -34.602 -59.615 1.00 49.74 ? 56 LEU B CA 1 ATOM 3427 C C . LEU B 1 56 ? -6.541 -33.180 -59.414 1.00 53.78 ? 56 LEU B C 1 ATOM 3428 O O . LEU B 1 56 ? -7.155 -32.614 -60.322 1.00 53.70 ? 56 LEU B O 1 ATOM 3429 C CB . LEU B 1 56 ? -6.609 -35.586 -58.594 1.00 48.89 ? 56 LEU B CB 1 ATOM 3430 C CG . LEU B 1 56 ? -8.167 -35.745 -58.538 1.00 51.52 ? 56 LEU B CG 1 ATOM 3431 C CD1 . LEU B 1 56 ? -8.794 -35.837 -59.902 1.00 50.59 ? 56 LEU B CD1 1 ATOM 3432 C CD2 . LEU B 1 56 ? -8.549 -36.988 -57.798 1.00 52.10 ? 56 LEU B CD2 1 ATOM 3433 N N . ARG B 1 57 ? -6.255 -32.594 -58.245 1.00 48.93 ? 57 ARG B N 1 ATOM 3434 C CA . ARG B 1 57 ? -6.737 -31.282 -57.840 1.00 47.95 ? 57 ARG B CA 1 ATOM 3435 C C . ARG B 1 57 ? -5.748 -30.682 -56.828 1.00 52.22 ? 57 ARG B C 1 ATOM 3436 O O . ARG B 1 57 ? -5.063 -31.424 -56.128 1.00 52.62 ? 57 ARG B O 1 ATOM 3437 C CB . ARG B 1 57 ? -8.134 -31.499 -57.231 1.00 46.74 ? 57 ARG B CB 1 ATOM 3438 C CG . ARG B 1 57 ? -8.938 -30.283 -56.877 1.00 49.60 ? 57 ARG B CG 1 ATOM 3439 C CD . ARG B 1 57 ? -10.258 -30.726 -56.272 1.00 49.86 ? 57 ARG B CD 1 ATOM 3440 N NE . ARG B 1 57 ? -11.279 -30.962 -57.290 1.00 52.85 ? 57 ARG B NE 1 ATOM 3441 C CZ . ARG B 1 57 ? -12.546 -31.267 -57.030 1.00 69.43 ? 57 ARG B CZ 1 ATOM 3442 N NH1 . ARG B 1 57 ? -12.962 -31.404 -55.778 1.00 59.26 ? 57 ARG B NH1 1 ATOM 3443 N NH2 . ARG B 1 57 ? -13.407 -31.438 -58.018 1.00 65.47 ? 57 ARG B NH2 1 ATOM 3444 N N . LYS B 1 58 ? -5.648 -29.346 -56.788 1.00 49.44 ? 58 LYS B N 1 ATOM 3445 C CA . LYS B 1 58 ? -4.774 -28.565 -55.891 1.00 49.09 ? 58 LYS B CA 1 ATOM 3446 C C . LYS B 1 58 ? -5.692 -27.670 -55.035 1.00 52.13 ? 58 LYS B C 1 ATOM 3447 O O . LYS B 1 58 ? -6.533 -26.966 -55.611 1.00 51.93 ? 58 LYS B O 1 ATOM 3448 C CB . LYS B 1 58 ? -3.804 -27.720 -56.737 1.00 50.60 ? 58 LYS B CB 1 ATOM 3449 C CG . LYS B 1 58 ? -2.855 -26.818 -55.964 1.00 62.99 ? 58 LYS B CG 1 ATOM 3450 C CD . LYS B 1 58 ? -2.250 -25.707 -56.847 1.00 70.15 ? 58 LYS B CD 1 ATOM 3451 C CE . LYS B 1 58 ? -0.994 -26.102 -57.589 1.00 78.51 ? 58 LYS B CE 1 ATOM 3452 N NZ . LYS B 1 58 ? -0.463 -24.980 -58.420 1.00 86.84 ? 58 LYS B NZ 1 ATOM 3453 N N . TYR B 1 59 ? -5.574 -27.732 -53.682 1.00 45.70 ? 59 TYR B N 1 ATOM 3454 C CA . TYR B 1 59 ? -6.423 -26.931 -52.787 1.00 44.33 ? 59 TYR B CA 1 ATOM 3455 C C . TYR B 1 59 ? -5.705 -25.823 -52.054 1.00 52.60 ? 59 TYR B C 1 ATOM 3456 O O . TYR B 1 59 ? -4.549 -25.974 -51.688 1.00 53.10 ? 59 TYR B O 1 ATOM 3457 C CB . TYR B 1 59 ? -7.058 -27.793 -51.721 1.00 42.93 ? 59 TYR B CB 1 ATOM 3458 C CG . TYR B 1 59 ? -8.135 -28.736 -52.184 1.00 41.11 ? 59 TYR B CG 1 ATOM 3459 C CD1 . TYR B 1 59 ? -9.469 -28.342 -52.195 1.00 42.50 ? 59 TYR B CD1 1 ATOM 3460 C CD2 . TYR B 1 59 ? -7.856 -30.077 -52.412 1.00 41.41 ? 59 TYR B CD2 1 ATOM 3461 C CE1 . TYR B 1 59 ? -10.490 -29.239 -52.494 1.00 43.59 ? 59 TYR B CE1 1 ATOM 3462 C CE2 . TYR B 1 59 ? -8.870 -30.990 -52.675 1.00 42.74 ? 59 TYR B CE2 1 ATOM 3463 C CZ . TYR B 1 59 ? -10.185 -30.563 -52.737 1.00 50.24 ? 59 TYR B CZ 1 ATOM 3464 O OH . TYR B 1 59 ? -11.165 -31.451 -53.095 1.00 47.87 ? 59 TYR B OH 1 ATOM 3465 N N . CYS B 1 60 ? -6.415 -24.736 -51.766 1.00 52.92 ? 60 CYS B N 1 ATOM 3466 C CA . CYS B 1 60 ? -5.872 -23.638 -50.979 1.00 54.46 ? 60 CYS B CA 1 ATOM 3467 C C . CYS B 1 60 ? -6.223 -23.883 -49.529 1.00 58.76 ? 60 CYS B C 1 ATOM 3468 O O . CYS B 1 60 ? -7.399 -24.121 -49.211 1.00 57.31 ? 60 CYS B O 1 ATOM 3469 C CB . CYS B 1 60 ? -6.385 -22.285 -51.453 1.00 55.55 ? 60 CYS B CB 1 ATOM 3470 S SG . CYS B 1 60 ? -5.497 -20.886 -50.733 1.00 60.59 ? 60 CYS B SG 1 ATOM 3471 N N . ILE B 1 61 ? -5.195 -23.831 -48.653 1.00 56.39 ? 61 ILE B N 1 ATOM 3472 C CA . ILE B 1 61 ? -5.335 -24.052 -47.209 1.00 56.79 ? 61 ILE B CA 1 ATOM 3473 C C . ILE B 1 61 ? -5.055 -22.776 -46.401 1.00 57.38 ? 61 ILE B C 1 ATOM 3474 O O . ILE B 1 61 ? -5.511 -22.667 -45.262 1.00 56.29 ? 61 ILE B O 1 ATOM 3475 C CB . ILE B 1 61 ? -4.533 -25.280 -46.709 1.00 61.36 ? 61 ILE B CB 1 ATOM 3476 C CG1 . ILE B 1 61 ? -3.030 -25.151 -46.956 1.00 61.59 ? 61 ILE B CG1 1 ATOM 3477 C CG2 . ILE B 1 61 ? -5.069 -26.559 -47.334 1.00 63.88 ? 61 ILE B CG2 1 ATOM 3478 C CD1 . ILE B 1 61 ? -2.291 -25.384 -45.778 1.00 70.90 ? 61 ILE B CD1 1 ATOM 3479 N N . GLU B 1 62 ? -4.391 -21.794 -47.004 1.00 54.09 ? 62 GLU B N 1 ATOM 3480 C CA . GLU B 1 62 ? -4.173 -20.506 -46.351 1.00 55.79 ? 62 GLU B CA 1 ATOM 3481 C C . GLU B 1 62 ? -4.306 -19.401 -47.400 1.00 65.83 ? 62 GLU B C 1 ATOM 3482 O O . GLU B 1 62 ? -3.631 -19.455 -48.433 1.00 64.88 ? 62 GLU B O 1 ATOM 3483 C CB . GLU B 1 62 ? -2.813 -20.436 -45.649 1.00 56.92 ? 62 GLU B CB 1 ATOM 3484 C CG . GLU B 1 62 ? -2.609 -19.177 -44.827 1.00 62.71 ? 62 GLU B CG 1 ATOM 3485 C CD . GLU B 1 62 ? -1.360 -19.119 -43.975 1.00 83.68 ? 62 GLU B CD 1 ATOM 3486 O OE1 . GLU B 1 62 ? -0.761 -20.184 -43.699 1.00 107.18 ? 62 GLU B OE1 1 ATOM 3487 O OE2 . GLU B 1 62 ? -1.009 -18.002 -43.536 1.00 69.63 ? 62 GLU B OE2 1 ATOM 3488 N N . ALA B 1 63 ? -5.175 -18.403 -47.125 1.00 66.23 ? 63 ALA B N 1 ATOM 3489 C CA . ALA B 1 63 ? -5.428 -17.319 -48.062 1.00 67.75 ? 63 ALA B CA 1 ATOM 3490 C C . ALA B 1 63 ? -5.236 -15.932 -47.496 1.00 75.33 ? 63 ALA B C 1 ATOM 3491 O O . ALA B 1 63 ? -5.076 -15.781 -46.295 1.00 73.75 ? 63 ALA B O 1 ATOM 3492 C CB . ALA B 1 63 ? -6.815 -17.458 -48.651 1.00 68.43 ? 63 ALA B CB 1 ATOM 3493 N N . LYS B 1 64 ? -5.240 -14.916 -48.387 1.00 76.19 ? 64 LYS B N 1 ATOM 3494 C CA . LYS B 1 64 ? -5.072 -13.492 -48.088 1.00 76.55 ? 64 LYS B CA 1 ATOM 3495 C C . LYS B 1 64 ? -6.033 -12.630 -48.917 1.00 82.04 ? 64 LYS B C 1 ATOM 3496 O O . LYS B 1 64 ? -6.086 -12.759 -50.147 1.00 82.16 ? 64 LYS B O 1 ATOM 3497 C CB . LYS B 1 64 ? -3.623 -13.074 -48.349 1.00 78.55 ? 64 LYS B CB 1 ATOM 3498 C CG . LYS B 1 64 ? -3.204 -11.866 -47.544 1.00 99.06 ? 64 LYS B CG 1 ATOM 3499 C CD . LYS B 1 64 ? -1.713 -11.554 -47.732 1.00 112.66 ? 64 LYS B CD 1 ATOM 3500 C CE . LYS B 1 64 ? -1.442 -10.440 -48.727 1.00 123.06 ? 64 LYS B CE 1 ATOM 3501 N NZ . LYS B 1 64 ? -1.711 -10.851 -50.135 1.00 132.75 ? 64 LYS B NZ 1 ATOM 3502 N N . LEU B 1 65 ? -6.797 -11.758 -48.239 1.00 78.83 ? 65 LEU B N 1 ATOM 3503 C CA . LEU B 1 65 ? -7.719 -10.849 -48.925 1.00 77.76 ? 65 LEU B CA 1 ATOM 3504 C C . LEU B 1 65 ? -7.140 -9.460 -48.937 1.00 81.65 ? 65 LEU B C 1 ATOM 3505 O O . LEU B 1 65 ? -6.802 -8.920 -47.881 1.00 81.00 ? 65 LEU B O 1 ATOM 3506 C CB . LEU B 1 65 ? -9.115 -10.818 -48.296 1.00 77.04 ? 65 LEU B CB 1 ATOM 3507 C CG . LEU B 1 65 ? -9.972 -12.036 -48.449 1.00 80.74 ? 65 LEU B CG 1 ATOM 3508 C CD1 . LEU B 1 65 ? -11.180 -11.913 -47.569 1.00 80.57 ? 65 LEU B CD1 1 ATOM 3509 C CD2 . LEU B 1 65 ? -10.354 -12.290 -49.903 1.00 82.59 ? 65 LEU B CD2 1 ATOM 3510 N N . THR B 1 66 ? -7.006 -8.904 -50.141 1.00 78.66 ? 66 THR B N 1 ATOM 3511 C CA . THR B 1 66 ? -6.488 -7.569 -50.430 1.00 78.88 ? 66 THR B CA 1 ATOM 3512 C C . THR B 1 66 ? -7.506 -6.818 -51.320 1.00 84.65 ? 66 THR B C 1 ATOM 3513 O O . THR B 1 66 ? -8.566 -7.366 -51.639 1.00 83.75 ? 66 THR B O 1 ATOM 3514 C CB . THR B 1 66 ? -5.120 -7.693 -51.154 1.00 84.25 ? 66 THR B CB 1 ATOM 3515 O OG1 . THR B 1 66 ? -5.236 -8.565 -52.282 1.00 85.48 ? 66 THR B OG1 1 ATOM 3516 C CG2 . THR B 1 66 ? -4.012 -8.190 -50.243 1.00 81.89 ? 66 THR B CG2 1 ATOM 3517 N N . ASN B 1 67 ? -7.179 -5.570 -51.711 1.00 82.51 ? 67 ASN B N 1 ATOM 3518 C CA . ASN B 1 67 ? -7.945 -4.729 -52.633 1.00 82.79 ? 67 ASN B CA 1 ATOM 3519 C C . ASN B 1 67 ? -9.466 -4.642 -52.354 1.00 90.12 ? 67 ASN B C 1 ATOM 3520 O O . ASN B 1 67 ? -10.258 -4.608 -53.307 1.00 91.01 ? 67 ASN B O 1 ATOM 3521 C CB . ASN B 1 67 ? -7.692 -5.213 -54.063 1.00 81.69 ? 67 ASN B CB 1 ATOM 3522 C CG . ASN B 1 67 ? -6.244 -5.203 -54.464 1.00 109.36 ? 67 ASN B CG 1 ATOM 3523 O OD1 . ASN B 1 67 ? -5.474 -6.118 -54.113 1.00 99.67 ? 67 ASN B OD1 1 ATOM 3524 N ND2 . ASN B 1 67 ? -5.863 -4.155 -55.207 1.00 105.65 ? 67 ASN B ND2 1 ATOM 3525 N N . THR B 1 68 ? -9.880 -4.606 -51.068 1.00 87.52 ? 68 THR B N 1 ATOM 3526 C CA . THR B 1 68 ? -11.303 -4.539 -50.718 1.00 87.98 ? 68 THR B CA 1 ATOM 3527 C C . THR B 1 68 ? -11.944 -3.249 -51.229 1.00 94.60 ? 68 THR B C 1 ATOM 3528 O O . THR B 1 68 ? -11.484 -2.152 -50.901 1.00 95.01 ? 68 THR B O 1 ATOM 3529 C CB . THR B 1 68 ? -11.515 -4.787 -49.235 1.00 96.76 ? 68 THR B CB 1 ATOM 3530 O OG1 . THR B 1 68 ? -11.087 -6.117 -48.950 1.00 98.97 ? 68 THR B OG1 1 ATOM 3531 C CG2 . THR B 1 68 ? -12.968 -4.630 -48.819 1.00 95.93 ? 68 THR B CG2 1 ATOM 3532 N N . THR B 1 69 ? -12.989 -3.403 -52.071 1.00 92.00 ? 69 THR B N 1 ATOM 3533 C CA . THR B 1 69 ? -13.742 -2.325 -52.734 1.00 91.82 ? 69 THR B CA 1 ATOM 3534 C C . THR B 1 69 ? -15.279 -2.502 -52.594 1.00 96.23 ? 69 THR B C 1 ATOM 3535 O O . THR B 1 69 ? -15.790 -3.602 -52.821 1.00 95.47 ? 69 THR B O 1 ATOM 3536 C CB . THR B 1 69 ? -13.305 -2.233 -54.212 1.00 98.58 ? 69 THR B CB 1 ATOM 3537 O OG1 . THR B 1 69 ? -13.468 -3.504 -54.843 1.00 96.13 ? 69 THR B OG1 1 ATOM 3538 C CG2 . THR B 1 69 ? -11.844 -1.788 -54.378 1.00 99.53 ? 69 THR B CG2 1 ATOM 3539 N N . THR B 1 70 ? -16.011 -1.421 -52.238 1.00 93.28 ? 70 THR B N 1 ATOM 3540 C CA . THR B 1 70 ? -17.478 -1.473 -52.077 1.00 93.00 ? 70 THR B CA 1 ATOM 3541 C C . THR B 1 70 ? -18.273 -0.402 -52.836 1.00 95.84 ? 70 THR B C 1 ATOM 3542 O O . THR B 1 70 ? -17.992 0.791 -52.691 1.00 95.86 ? 70 THR B O 1 ATOM 3543 C CB . THR B 1 70 ? -17.853 -1.434 -50.591 1.00 103.40 ? 70 THR B CB 1 ATOM 3544 O OG1 . THR B 1 70 ? -17.333 -2.600 -49.954 1.00 104.00 ? 70 THR B OG1 1 ATOM 3545 C CG2 . THR B 1 70 ? -19.368 -1.329 -50.356 1.00 102.80 ? 70 THR B CG2 1 ATOM 3546 N N . GLU B 1 71 ? -19.322 -0.830 -53.576 1.00 90.83 ? 71 GLU B N 1 ATOM 3547 C CA . GLU B 1 71 ? -20.242 0.085 -54.244 1.00 89.95 ? 71 GLU B CA 1 ATOM 3548 C C . GLU B 1 71 ? -21.647 -0.091 -53.683 1.00 91.23 ? 71 GLU B C 1 ATOM 3549 O O . GLU B 1 71 ? -22.144 -1.210 -53.577 1.00 89.79 ? 71 GLU B O 1 ATOM 3550 C CB . GLU B 1 71 ? -20.241 -0.077 -55.763 1.00 91.44 ? 71 GLU B CB 1 ATOM 3551 C CG . GLU B 1 71 ? -20.885 1.097 -56.488 1.00 101.89 ? 71 GLU B CG 1 ATOM 3552 C CD . GLU B 1 71 ? -20.883 1.008 -58.005 1.00 117.96 ? 71 GLU B CD 1 ATOM 3553 O OE1 . GLU B 1 71 ? -19.843 1.335 -58.623 1.00 101.41 ? 71 GLU B OE1 1 ATOM 3554 O OE2 . GLU B 1 71 ? -21.930 0.629 -58.578 1.00 110.69 ? 71 GLU B OE2 1 ATOM 3555 N N . SER B 1 72 ? -22.275 1.023 -53.308 1.00 86.74 ? 72 SER B N 1 ATOM 3556 C CA . SER B 1 72 ? -23.639 1.035 -52.785 1.00 85.52 ? 72 SER B CA 1 ATOM 3557 C C . SER B 1 72 ? -24.591 1.828 -53.702 1.00 88.84 ? 72 SER B C 1 ATOM 3558 O O . SER B 1 72 ? -24.156 2.456 -54.671 1.00 89.52 ? 72 SER B O 1 ATOM 3559 C CB . SER B 1 72 ? -23.671 1.570 -51.356 1.00 86.55 ? 72 SER B CB 1 ATOM 3560 O OG . SER B 1 72 ? -22.890 2.748 -51.264 1.00 91.70 ? 72 SER B OG 1 ATOM 3561 N N . ARG B 1 73 ? -25.895 1.725 -53.430 1.00 83.06 ? 73 ARG B N 1 ATOM 3562 C CA . ARG B 1 73 ? -26.977 2.406 -54.136 1.00 81.38 ? 73 ARG B CA 1 ATOM 3563 C C . ARG B 1 73 ? -28.025 2.782 -53.089 1.00 84.25 ? 73 ARG B C 1 ATOM 3564 O O . ARG B 1 73 ? -28.188 2.078 -52.092 1.00 83.90 ? 73 ARG B O 1 ATOM 3565 C CB . ARG B 1 73 ? -27.618 1.505 -55.223 1.00 77.52 ? 73 ARG B CB 1 ATOM 3566 C CG . ARG B 1 73 ? -26.776 1.256 -56.464 1.00 80.16 ? 73 ARG B CG 1 ATOM 3567 C CD . ARG B 1 73 ? -26.927 2.319 -57.530 1.00 93.77 ? 73 ARG B CD 1 ATOM 3568 N NE . ARG B 1 73 ? -26.296 1.931 -58.802 1.00 103.75 ? 73 ARG B NE 1 ATOM 3569 C CZ . ARG B 1 73 ? -25.035 2.197 -59.148 1.00 108.61 ? 73 ARG B CZ 1 ATOM 3570 N NH1 . ARG B 1 73 ? -24.233 2.856 -58.316 1.00 74.44 ? 73 ARG B NH1 1 ATOM 3571 N NH2 . ARG B 1 73 ? -24.566 1.798 -60.324 1.00 101.91 ? 73 ARG B NH2 1 ATOM 3572 N N . CYS B 1 74 ? -28.725 3.884 -53.304 1.00 80.43 ? 74 CYS B N 1 ATOM 3573 C CA . CYS B 1 74 ? -29.793 4.286 -52.402 1.00 80.89 ? 74 CYS B CA 1 ATOM 3574 C C . CYS B 1 74 ? -31.007 3.441 -52.738 1.00 85.63 ? 74 CYS B C 1 ATOM 3575 O O . CYS B 1 74 ? -31.018 2.839 -53.815 1.00 83.78 ? 74 CYS B O 1 ATOM 3576 C CB . CYS B 1 74 ? -30.092 5.775 -52.539 1.00 81.75 ? 74 CYS B CB 1 ATOM 3577 S SG . CYS B 1 74 ? -29.160 6.836 -51.402 1.00 85.94 ? 74 CYS B SG 1 ATOM 3578 N N . PRO B 1 75 ? -32.039 3.320 -51.867 1.00 85.24 ? 75 PRO B N 1 ATOM 3579 C CA . PRO B 1 75 ? -33.200 2.500 -52.252 1.00 86.21 ? 75 PRO B CA 1 ATOM 3580 C C . PRO B 1 75 ? -33.795 3.036 -53.543 1.00 95.14 ? 75 PRO B C 1 ATOM 3581 O O . PRO B 1 75 ? -33.726 4.254 -53.784 1.00 95.94 ? 75 PRO B O 1 ATOM 3582 C CB . PRO B 1 75 ? -34.160 2.679 -51.075 1.00 87.38 ? 75 PRO B CB 1 ATOM 3583 C CG . PRO B 1 75 ? -33.304 3.069 -49.958 1.00 91.24 ? 75 PRO B CG 1 ATOM 3584 C CD . PRO B 1 75 ? -32.252 3.932 -50.543 1.00 86.36 ? 75 PRO B CD 1 ATOM 3585 N N . THR B 1 76 ? -34.322 2.135 -54.406 1.00 93.66 ? 76 THR B N 1 ATOM 3586 C CA . THR B 1 76 ? -34.948 2.464 -55.707 1.00 94.09 ? 76 THR B CA 1 ATOM 3587 C C . THR B 1 76 ? -33.945 2.953 -56.771 1.00 98.11 ? 76 THR B C 1 ATOM 3588 O O . THR B 1 76 ? -34.369 3.241 -57.889 1.00 98.82 ? 76 THR B O 1 ATOM 3589 C CB . THR B 1 76 ? -36.153 3.481 -55.590 1.00 104.17 ? 76 THR B CB 1 ATOM 3590 O OG1 . THR B 1 76 ? -35.679 4.838 -55.693 1.00 107.35 ? 76 THR B OG1 1 ATOM 3591 C CG2 . THR B 1 76 ? -37.022 3.288 -54.329 1.00 98.92 ? 76 THR B CG2 1 ATOM 3592 N N . GLN B 1 77 ? -32.646 3.073 -56.435 1.00 93.90 ? 77 GLN B N 1 ATOM 3593 C CA . GLN B 1 77 ? -31.616 3.554 -57.376 1.00 93.58 ? 77 GLN B CA 1 ATOM 3594 C C . GLN B 1 77 ? -30.953 2.436 -58.188 1.00 96.15 ? 77 GLN B C 1 ATOM 3595 O O . GLN B 1 77 ? -29.985 2.694 -58.910 1.00 96.73 ? 77 GLN B O 1 ATOM 3596 C CB . GLN B 1 77 ? -30.540 4.428 -56.687 1.00 94.94 ? 77 GLN B CB 1 ATOM 3597 C CG . GLN B 1 77 ? -31.085 5.565 -55.828 1.00 117.75 ? 77 GLN B CG 1 ATOM 3598 C CD . GLN B 1 77 ? -31.549 6.782 -56.574 1.00 145.31 ? 77 GLN B CD 1 ATOM 3599 O OE1 . GLN B 1 77 ? -30.897 7.247 -57.511 1.00 142.62 ? 77 GLN B OE1 1 ATOM 3600 N NE2 . GLN B 1 77 ? -32.639 7.377 -56.099 1.00 141.50 ? 77 GLN B NE2 1 ATOM 3601 N N . GLY B 1 78 ? -31.480 1.222 -58.078 1.00 90.49 ? 78 GLY B N 1 ATOM 3602 C CA . GLY B 1 78 ? -30.937 0.069 -58.781 1.00 89.90 ? 78 GLY B CA 1 ATOM 3603 C C . GLY B 1 78 ? -29.983 -0.775 -57.956 1.00 92.23 ? 78 GLY B C 1 ATOM 3604 O O . GLY B 1 78 ? -29.830 -0.568 -56.739 1.00 93.15 ? 78 GLY B O 1 ATOM 3605 N N . GLU B 1 79 ? -29.353 -1.754 -58.634 1.00 85.38 ? 79 GLU B N 1 ATOM 3606 C CA . GLU B 1 79 ? -28.395 -2.703 -58.064 1.00 83.95 ? 79 GLU B CA 1 ATOM 3607 C C . GLU B 1 79 ? -26.977 -2.190 -58.347 1.00 83.18 ? 79 GLU B C 1 ATOM 3608 O O . GLU B 1 79 ? -26.722 -1.734 -59.463 1.00 84.26 ? 79 GLU B O 1 ATOM 3609 C CB . GLU B 1 79 ? -28.605 -4.099 -58.684 1.00 85.55 ? 79 GLU B CB 1 ATOM 3610 C CG . GLU B 1 79 ? -28.437 -5.266 -57.715 1.00 98.31 ? 79 GLU B CG 1 ATOM 3611 C CD . GLU B 1 79 ? -28.433 -6.650 -58.349 1.00 123.81 ? 79 GLU B CD 1 ATOM 3612 O OE1 . GLU B 1 79 ? -27.906 -6.791 -59.477 1.00 124.29 ? 79 GLU B OE1 1 ATOM 3613 O OE2 . GLU B 1 79 ? -28.930 -7.604 -57.706 1.00 110.19 ? 79 GLU B OE2 1 ATOM 3614 N N . PRO B 1 80 ? -26.045 -2.194 -57.379 1.00 74.30 ? 80 PRO B N 1 ATOM 3615 C CA . PRO B 1 80 ? -24.702 -1.687 -57.686 1.00 73.73 ? 80 PRO B CA 1 ATOM 3616 C C . PRO B 1 80 ? -23.842 -2.726 -58.401 1.00 79.46 ? 80 PRO B C 1 ATOM 3617 O O . PRO B 1 80 ? -24.160 -3.928 -58.397 1.00 80.90 ? 80 PRO B O 1 ATOM 3618 C CB . PRO B 1 80 ? -24.141 -1.289 -56.324 1.00 75.32 ? 80 PRO B CB 1 ATOM 3619 C CG . PRO B 1 80 ? -24.941 -2.059 -55.328 1.00 79.68 ? 80 PRO B CG 1 ATOM 3620 C CD . PRO B 1 80 ? -26.129 -2.695 -55.998 1.00 75.08 ? 80 PRO B CD 1 ATOM 3621 N N . SER B 1 81 ? -22.774 -2.263 -59.068 1.00 73.61 ? 81 SER B N 1 ATOM 3622 C CA . SER B 1 81 ? -21.909 -3.172 -59.812 1.00 71.68 ? 81 SER B CA 1 ATOM 3623 C C . SER B 1 81 ? -20.461 -2.706 -59.849 1.00 75.42 ? 81 SER B C 1 ATOM 3624 O O . SER B 1 81 ? -20.193 -1.499 -59.937 1.00 76.67 ? 81 SER B O 1 ATOM 3625 C CB . SER B 1 81 ? -22.428 -3.373 -61.232 1.00 71.95 ? 81 SER B CB 1 ATOM 3626 O OG . SER B 1 81 ? -22.070 -2.264 -62.037 1.00 79.61 ? 81 SER B OG 1 ATOM 3627 N N . LEU B 1 82 ? -19.530 -3.679 -59.815 1.00 68.57 ? 82 LEU B N 1 ATOM 3628 C CA . LEU B 1 82 ? -18.099 -3.457 -59.927 1.00 65.87 ? 82 LEU B CA 1 ATOM 3629 C C . LEU B 1 82 ? -17.632 -4.289 -61.097 1.00 66.97 ? 82 LEU B C 1 ATOM 3630 O O . LEU B 1 82 ? -18.314 -5.246 -61.474 1.00 63.80 ? 82 LEU B O 1 ATOM 3631 C CB . LEU B 1 82 ? -17.374 -3.846 -58.637 1.00 65.44 ? 82 LEU B CB 1 ATOM 3632 C CG . LEU B 1 82 ? -17.776 -3.084 -57.351 1.00 69.42 ? 82 LEU B CG 1 ATOM 3633 C CD1 . LEU B 1 82 ? -17.132 -3.705 -56.127 1.00 68.84 ? 82 LEU B CD1 1 ATOM 3634 C CD2 . LEU B 1 82 ? -17.391 -1.629 -57.427 1.00 72.53 ? 82 LEU B CD2 1 ATOM 3635 N N . ASN B 1 83 ? -16.509 -3.892 -61.724 1.00 65.85 ? 83 ASN B N 1 ATOM 3636 C CA . ASN B 1 83 ? -15.940 -4.620 -62.886 1.00 66.33 ? 83 ASN B CA 1 ATOM 3637 C C . ASN B 1 83 ? -15.438 -5.974 -62.398 1.00 68.86 ? 83 ASN B C 1 ATOM 3638 O O . ASN B 1 83 ? -15.664 -7.002 -63.045 1.00 66.90 ? 83 ASN B O 1 ATOM 3639 C CB . ASN B 1 83 ? -14.804 -3.823 -63.539 1.00 67.88 ? 83 ASN B CB 1 ATOM 3640 C CG . ASN B 1 83 ? -15.191 -2.391 -63.805 1.00 94.63 ? 83 ASN B CG 1 ATOM 3641 O OD1 . ASN B 1 83 ? -15.786 -2.080 -64.843 1.00 88.65 ? 83 ASN B OD1 1 ATOM 3642 N ND2 . ASN B 1 83 ? -14.956 -1.507 -62.822 1.00 84.47 ? 83 ASN B ND2 1 ATOM 3643 N N . GLU B 1 84 ? -14.820 -5.938 -61.193 1.00 64.28 ? 84 GLU B N 1 ATOM 3644 C CA . GLU B 1 84 ? -14.310 -7.007 -60.366 1.00 63.10 ? 84 GLU B CA 1 ATOM 3645 C C . GLU B 1 84 ? -15.154 -8.272 -60.414 1.00 68.94 ? 84 GLU B C 1 ATOM 3646 O O . GLU B 1 84 ? -14.598 -9.368 -60.341 1.00 70.66 ? 84 GLU B O 1 ATOM 3647 C CB . GLU B 1 84 ? -14.239 -6.487 -58.944 1.00 63.91 ? 84 GLU B CB 1 ATOM 3648 C CG . GLU B 1 84 ? -12.963 -5.731 -58.656 1.00 77.52 ? 84 GLU B CG 1 ATOM 3649 C CD . GLU B 1 84 ? -12.872 -4.289 -59.117 1.00 114.30 ? 84 GLU B CD 1 ATOM 3650 O OE1 . GLU B 1 84 ? -12.970 -4.036 -60.342 1.00 112.54 ? 84 GLU B OE1 1 ATOM 3651 O OE2 . GLU B 1 84 ? -12.592 -3.424 -58.254 1.00 113.96 ? 84 GLU B OE2 1 ATOM 3652 N N . GLU B 1 85 ? -16.483 -8.131 -60.557 1.00 65.00 ? 85 GLU B N 1 ATOM 3653 C CA . GLU B 1 85 ? -17.429 -9.247 -60.648 1.00 65.45 ? 85 GLU B CA 1 ATOM 3654 C C . GLU B 1 85 ? -17.170 -10.096 -61.873 1.00 71.03 ? 85 GLU B C 1 ATOM 3655 O O . GLU B 1 85 ? -17.736 -11.177 -62.008 1.00 70.50 ? 85 GLU B O 1 ATOM 3656 C CB . GLU B 1 85 ? -18.870 -8.743 -60.668 1.00 67.01 ? 85 GLU B CB 1 ATOM 3657 C CG . GLU B 1 85 ? -19.210 -7.842 -59.496 1.00 77.35 ? 85 GLU B CG 1 ATOM 3658 C CD . GLU B 1 85 ? -20.597 -7.264 -59.625 1.00 88.57 ? 85 GLU B CD 1 ATOM 3659 O OE1 . GLU B 1 85 ? -21.570 -7.941 -59.224 1.00 79.11 ? 85 GLU B OE1 1 ATOM 3660 O OE2 . GLU B 1 85 ? -20.715 -6.163 -60.202 1.00 76.37 ? 85 GLU B OE2 1 ATOM 3661 N N . GLN B 1 86 ? -16.285 -9.609 -62.748 1.00 70.00 ? 86 GLN B N 1 ATOM 3662 C CA . GLN B 1 86 ? -15.853 -10.250 -64.000 1.00 70.39 ? 86 GLN B CA 1 ATOM 3663 C C . GLN B 1 86 ? -14.363 -10.725 -63.895 1.00 70.58 ? 86 GLN B C 1 ATOM 3664 O O . GLN B 1 86 ? -13.921 -11.590 -64.662 1.00 68.40 ? 86 GLN B O 1 ATOM 3665 C CB . GLN B 1 86 ? -16.164 -9.330 -65.214 1.00 72.21 ? 86 GLN B CB 1 ATOM 3666 C CG . GLN B 1 86 ? -17.661 -8.886 -65.243 1.00 96.65 ? 86 GLN B CG 1 ATOM 3667 C CD . GLN B 1 86 ? -18.027 -7.738 -66.177 1.00 119.09 ? 86 GLN B CD 1 ATOM 3668 O OE1 . GLN B 1 86 ? -17.300 -6.735 -66.321 1.00 114.84 ? 86 GLN B OE1 1 ATOM 3669 N NE2 . GLN B 1 86 ? -19.219 -7.830 -66.776 1.00 104.65 ? 86 GLN B NE2 1 ATOM 3670 N N . ASP B 1 87 ? -13.637 -10.220 -62.868 1.00 65.59 ? 87 ASP B N 1 ATOM 3671 C CA . ASP B 1 87 ? -12.279 -10.660 -62.560 1.00 64.72 ? 87 ASP B CA 1 ATOM 3672 C C . ASP B 1 87 ? -12.396 -11.963 -61.743 1.00 69.28 ? 87 ASP B C 1 ATOM 3673 O O . ASP B 1 87 ? -13.014 -11.972 -60.662 1.00 70.77 ? 87 ASP B O 1 ATOM 3674 C CB . ASP B 1 87 ? -11.503 -9.579 -61.782 1.00 65.73 ? 87 ASP B CB 1 ATOM 3675 C CG . ASP B 1 87 ? -9.988 -9.763 -61.747 1.00 73.96 ? 87 ASP B CG 1 ATOM 3676 O OD1 . ASP B 1 87 ? -9.497 -10.840 -62.166 1.00 72.35 ? 87 ASP B OD1 1 ATOM 3677 O OD2 . ASP B 1 87 ? -9.293 -8.825 -61.331 1.00 83.82 ? 87 ASP B OD2 1 ATOM 3678 N N . LYS B 1 88 ? -11.838 -13.061 -62.271 1.00 63.53 ? 88 LYS B N 1 ATOM 3679 C CA . LYS B 1 88 ? -11.920 -14.360 -61.620 1.00 63.07 ? 88 LYS B CA 1 ATOM 3680 C C . LYS B 1 88 ? -10.923 -14.552 -60.463 1.00 67.11 ? 88 LYS B C 1 ATOM 3681 O O . LYS B 1 88 ? -10.751 -15.680 -59.989 1.00 68.91 ? 88 LYS B O 1 ATOM 3682 C CB . LYS B 1 88 ? -11.779 -15.479 -62.655 1.00 66.67 ? 88 LYS B CB 1 ATOM 3683 C CG . LYS B 1 88 ? -13.007 -15.744 -63.520 1.00 92.42 ? 88 LYS B CG 1 ATOM 3684 C CD . LYS B 1 88 ? -12.597 -16.530 -64.784 1.00 109.74 ? 88 LYS B CD 1 ATOM 3685 C CE . LYS B 1 88 ? -13.605 -17.564 -65.236 1.00 124.22 ? 88 LYS B CE 1 ATOM 3686 N NZ . LYS B 1 88 ? -13.185 -18.234 -66.500 1.00 132.13 ? 88 LYS B NZ 1 ATOM 3687 N N . ARG B 1 89 ? -10.289 -13.470 -59.993 1.00 61.31 ? 89 ARG B N 1 ATOM 3688 C CA . ARG B 1 89 ? -9.307 -13.491 -58.901 1.00 60.15 ? 89 ARG B CA 1 ATOM 3689 C C . ARG B 1 89 ? -9.885 -12.753 -57.715 1.00 65.52 ? 89 ARG B C 1 ATOM 3690 O O . ARG B 1 89 ? -9.234 -12.583 -56.678 1.00 66.66 ? 89 ARG B O 1 ATOM 3691 C CB . ARG B 1 89 ? -8.005 -12.818 -59.365 1.00 56.55 ? 89 ARG B CB 1 ATOM 3692 C CG . ARG B 1 89 ? -7.423 -13.518 -60.586 1.00 62.98 ? 89 ARG B CG 1 ATOM 3693 C CD . ARG B 1 89 ? -6.281 -12.760 -61.205 1.00 76.22 ? 89 ARG B CD 1 ATOM 3694 N NE . ARG B 1 89 ? -6.680 -11.489 -61.817 1.00 82.58 ? 89 ARG B NE 1 ATOM 3695 C CZ . ARG B 1 89 ? -5.956 -10.374 -61.753 1.00 92.65 ? 89 ARG B CZ 1 ATOM 3696 N NH1 . ARG B 1 89 ? -4.797 -10.360 -61.096 1.00 64.94 ? 89 ARG B NH1 1 ATOM 3697 N NH2 . ARG B 1 89 ? -6.384 -9.265 -62.339 1.00 83.86 ? 89 ARG B NH2 1 ATOM 3698 N N . PHE B 1 90 ? -11.117 -12.297 -57.887 1.00 61.26 ? 90 PHE B N 1 ATOM 3699 C CA . PHE B 1 90 ? -11.846 -11.519 -56.911 1.00 60.62 ? 90 PHE B CA 1 ATOM 3700 C C . PHE B 1 90 ? -12.992 -12.295 -56.346 1.00 64.56 ? 90 PHE B C 1 ATOM 3701 O O . PHE B 1 90 ? -13.553 -13.176 -57.019 1.00 65.27 ? 90 PHE B O 1 ATOM 3702 C CB . PHE B 1 90 ? -12.342 -10.214 -57.559 1.00 62.05 ? 90 PHE B CB 1 ATOM 3703 C CG . PHE B 1 90 ? -11.320 -9.113 -57.440 1.00 63.04 ? 90 PHE B CG 1 ATOM 3704 C CD1 . PHE B 1 90 ? -11.267 -8.309 -56.305 1.00 65.19 ? 90 PHE B CD1 1 ATOM 3705 C CD2 . PHE B 1 90 ? -10.366 -8.922 -58.426 1.00 64.60 ? 90 PHE B CD2 1 ATOM 3706 C CE1 . PHE B 1 90 ? -10.294 -7.316 -56.173 1.00 67.18 ? 90 PHE B CE1 1 ATOM 3707 C CE2 . PHE B 1 90 ? -9.391 -7.932 -58.293 1.00 65.06 ? 90 PHE B CE2 1 ATOM 3708 C CZ . PHE B 1 90 ? -9.364 -7.135 -57.171 1.00 64.52 ? 90 PHE B CZ 1 ATOM 3709 N N . ILE B 1 91 ? -13.352 -11.969 -55.111 1.00 59.34 ? 91 ILE B N 1 ATOM 3710 C CA . ILE B 1 91 ? -14.476 -12.615 -54.446 1.00 59.36 ? 91 ILE B CA 1 ATOM 3711 C C . ILE B 1 91 ? -15.532 -11.533 -54.175 1.00 67.78 ? 91 ILE B C 1 ATOM 3712 O O . ILE B 1 91 ? -15.207 -10.500 -53.565 1.00 67.02 ? 91 ILE B O 1 ATOM 3713 C CB . ILE B 1 91 ? -14.026 -13.495 -53.212 1.00 60.89 ? 91 ILE B CB 1 ATOM 3714 C CG1 . ILE B 1 91 ? -15.206 -14.163 -52.487 1.00 60.19 ? 91 ILE B CG1 1 ATOM 3715 C CG2 . ILE B 1 91 ? -13.136 -12.747 -52.224 1.00 59.46 ? 91 ILE B CG2 1 ATOM 3716 C CD1 . ILE B 1 91 ? -15.699 -15.379 -53.109 1.00 66.04 ? 91 ILE B CD1 1 ATOM 3717 N N . CYS B 1 92 ? -16.765 -11.715 -54.727 1.00 66.85 ? 92 CYS B N 1 ATOM 3718 C CA . CYS B 1 92 ? -17.823 -10.709 -54.562 1.00 67.43 ? 92 CYS B CA 1 ATOM 3719 C C . CYS B 1 92 ? -19.075 -11.241 -53.888 1.00 71.40 ? 92 CYS B C 1 ATOM 3720 O O . CYS B 1 92 ? -19.373 -12.444 -53.943 1.00 70.62 ? 92 CYS B O 1 ATOM 3721 C CB . CYS B 1 92 ? -18.162 -10.018 -55.883 1.00 67.87 ? 92 CYS B CB 1 ATOM 3722 S SG . CYS B 1 92 ? -16.732 -9.310 -56.742 1.00 72.24 ? 92 CYS B SG 1 ATOM 3723 N N . LYS B 1 93 ? -19.826 -10.304 -53.281 1.00 67.52 ? 93 LYS B N 1 ATOM 3724 C CA . LYS B 1 93 ? -21.095 -10.570 -52.636 1.00 67.19 ? 93 LYS B CA 1 ATOM 3725 C C . LYS B 1 93 ? -21.932 -9.323 -52.647 1.00 72.54 ? 93 LYS B C 1 ATOM 3726 O O . LYS B 1 93 ? -21.447 -8.230 -52.329 1.00 70.99 ? 93 LYS B O 1 ATOM 3727 C CB . LYS B 1 93 ? -20.886 -11.072 -51.189 1.00 69.61 ? 93 LYS B CB 1 ATOM 3728 C CG . LYS B 1 93 ? -22.135 -11.163 -50.285 1.00 71.03 ? 93 LYS B CG 1 ATOM 3729 C CD . LYS B 1 93 ? -22.840 -12.510 -50.327 1.00 71.40 ? 93 LYS B CD 1 ATOM 3730 C CE . LYS B 1 93 ? -23.864 -12.668 -49.229 1.00 75.24 ? 93 LYS B CE 1 ATOM 3731 N NZ . LYS B 1 93 ? -23.246 -12.658 -47.873 1.00 90.70 ? 93 LYS B NZ 1 ATOM 3732 N N . HIS B 1 94 ? -23.212 -9.509 -52.997 1.00 72.12 ? 94 HIS B N 1 ATOM 3733 C CA . HIS B 1 94 ? -24.246 -8.490 -52.941 1.00 73.62 ? 94 HIS B CA 1 ATOM 3734 C C . HIS B 1 94 ? -25.007 -8.640 -51.638 1.00 77.86 ? 94 HIS B C 1 ATOM 3735 O O . HIS B 1 94 ? -25.291 -9.758 -51.211 1.00 77.55 ? 94 HIS B O 1 ATOM 3736 C CB . HIS B 1 94 ? -25.243 -8.683 -54.074 1.00 75.39 ? 94 HIS B CB 1 ATOM 3737 C CG . HIS B 1 94 ? -24.786 -8.109 -55.357 1.00 79.46 ? 94 HIS B CG 1 ATOM 3738 N ND1 . HIS B 1 94 ? -25.197 -6.862 -55.766 1.00 81.51 ? 94 HIS B ND1 1 ATOM 3739 C CD2 . HIS B 1 94 ? -23.962 -8.641 -56.291 1.00 81.90 ? 94 HIS B CD2 1 ATOM 3740 C CE1 . HIS B 1 94 ? -24.611 -6.669 -56.936 1.00 81.53 ? 94 HIS B CE1 1 ATOM 3741 N NE2 . HIS B 1 94 ? -23.859 -7.717 -57.294 1.00 81.88 ? 94 HIS B NE2 1 ATOM 3742 N N . SER B 1 95 ? -25.367 -7.525 -51.026 1.00 75.69 ? 95 SER B N 1 ATOM 3743 C CA . SER B 1 95 ? -26.168 -7.516 -49.812 1.00 76.42 ? 95 SER B CA 1 ATOM 3744 C C . SER B 1 95 ? -27.063 -6.288 -49.805 1.00 80.89 ? 95 SER B C 1 ATOM 3745 O O . SER B 1 95 ? -27.161 -5.592 -50.814 1.00 81.24 ? 95 SER B O 1 ATOM 3746 C CB . SER B 1 95 ? -25.292 -7.587 -48.563 1.00 81.62 ? 95 SER B CB 1 ATOM 3747 O OG . SER B 1 95 ? -25.838 -8.470 -47.595 1.00 91.84 ? 95 SER B OG 1 ATOM 3748 N N . MET B 1 96 ? -27.737 -6.042 -48.686 1.00 77.45 ? 96 MET B N 1 ATOM 3749 C CA . MET B 1 96 ? -28.683 -4.950 -48.497 1.00 76.68 ? 96 MET B CA 1 ATOM 3750 C C . MET B 1 96 ? -28.350 -4.239 -47.197 1.00 74.55 ? 96 MET B C 1 ATOM 3751 O O . MET B 1 96 ? -28.203 -4.884 -46.158 1.00 75.30 ? 96 MET B O 1 ATOM 3752 C CB . MET B 1 96 ? -30.108 -5.535 -48.362 1.00 79.87 ? 96 MET B CB 1 ATOM 3753 C CG . MET B 1 96 ? -30.605 -6.290 -49.575 1.00 84.59 ? 96 MET B CG 1 ATOM 3754 S SD . MET B 1 96 ? -31.552 -5.152 -50.615 1.00 90.20 ? 96 MET B SD 1 ATOM 3755 C CE . MET B 1 96 ? -30.729 -5.387 -52.206 1.00 87.30 ? 96 MET B CE 1 ATOM 3756 N N . VAL B 1 97 ? -28.275 -2.929 -47.237 1.00 65.62 ? 97 VAL B N 1 ATOM 3757 C CA . VAL B 1 97 ? -28.060 -2.128 -46.042 1.00 64.12 ? 97 VAL B CA 1 ATOM 3758 C C . VAL B 1 97 ? -29.254 -1.185 -45.817 1.00 69.09 ? 97 VAL B C 1 ATOM 3759 O O . VAL B 1 97 ? -30.027 -0.922 -46.737 1.00 69.52 ? 97 VAL B O 1 ATOM 3760 C CB . VAL B 1 97 ? -26.710 -1.364 -46.010 1.00 66.66 ? 97 VAL B CB 1 ATOM 3761 C CG1 . VAL B 1 97 ? -25.535 -2.309 -45.981 1.00 66.35 ? 97 VAL B CG1 1 ATOM 3762 C CG2 . VAL B 1 97 ? -26.576 -0.369 -47.141 1.00 66.15 ? 97 VAL B CG2 1 ATOM 3763 N N . ASP B 1 98 ? -29.395 -0.669 -44.599 1.00 64.86 ? 98 ASP B N 1 ATOM 3764 C CA . ASP B 1 98 ? -30.432 0.284 -44.273 1.00 63.95 ? 98 ASP B CA 1 ATOM 3765 C C . ASP B 1 98 ? -29.965 1.611 -44.767 1.00 68.24 ? 98 ASP B C 1 ATOM 3766 O O . ASP B 1 98 ? -28.875 2.085 -44.418 1.00 67.83 ? 98 ASP B O 1 ATOM 3767 C CB . ASP B 1 98 ? -30.708 0.378 -42.765 1.00 64.80 ? 98 ASP B CB 1 ATOM 3768 C CG . ASP B 1 98 ? -31.448 -0.791 -42.174 1.00 64.56 ? 98 ASP B CG 1 ATOM 3769 O OD1 . ASP B 1 98 ? -32.197 -1.473 -42.929 1.00 59.99 ? 98 ASP B OD1 1 ATOM 3770 O OD2 . ASP B 1 98 ? -31.304 -1.015 -40.951 1.00 70.95 ? 98 ASP B OD2 1 ATOM 3771 N N . ARG B 1 99 ? -30.788 2.189 -45.613 1.00 64.86 ? 99 ARG B N 1 ATOM 3772 C CA . ARG B 1 99 ? -30.567 3.494 -46.170 1.00 63.80 ? 99 ARG B CA 1 ATOM 3773 C C . ARG B 1 99 ? -31.716 4.387 -45.740 1.00 66.97 ? 99 ARG B C 1 ATOM 3774 O O . ARG B 1 99 ? -32.726 3.902 -45.228 1.00 63.51 ? 99 ARG B O 1 ATOM 3775 C CB . ARG B 1 99 ? -30.385 3.433 -47.698 1.00 60.65 ? 99 ARG B CB 1 ATOM 3776 C CG . ARG B 1 99 ? -29.112 2.751 -48.227 1.00 59.27 ? 99 ARG B CG 1 ATOM 3777 C CD . ARG B 1 99 ? -27.779 3.229 -47.660 1.00 59.49 ? 99 ARG B CD 1 ATOM 3778 N NE . ARG B 1 99 ? -27.370 4.567 -48.078 1.00 66.62 ? 99 ARG B NE 1 ATOM 3779 C CZ . ARG B 1 99 ? -26.694 4.846 -49.192 1.00 76.96 ? 99 ARG B CZ 1 ATOM 3780 N NH1 . ARG B 1 99 ? -26.415 3.882 -50.074 1.00 53.22 ? 99 ARG B NH1 1 ATOM 3781 N NH2 . ARG B 1 99 ? -26.346 6.096 -49.466 1.00 70.83 ? 99 ARG B NH2 1 ATOM 3782 N N . GLY B 1 100 ? -31.504 5.680 -45.906 1.00 67.41 ? 100 GLY B N 1 ATOM 3783 C CA . GLY B 1 100 ? -32.431 6.742 -45.550 1.00 69.03 ? 100 GLY B CA 1 ATOM 3784 C C . GLY B 1 100 ? -31.724 8.067 -45.341 1.00 75.48 ? 100 GLY B C 1 ATOM 3785 O O . GLY B 1 100 ? -30.529 8.203 -45.648 1.00 76.43 ? 100 GLY B O 1 ATOM 3786 N N . TRP B 1 101 ? -32.481 9.065 -44.836 1.00 71.52 ? 101 TRP B N 1 ATOM 3787 C CA . TRP B 1 101 ? -31.976 10.381 -44.503 1.00 71.62 ? 101 TRP B CA 1 ATOM 3788 C C . TRP B 1 101 ? -31.094 9.982 -43.313 1.00 80.02 ? 101 TRP B C 1 ATOM 3789 O O . TRP B 1 101 ? -31.427 9.049 -42.548 1.00 80.86 ? 101 TRP B O 1 ATOM 3790 C CB . TRP B 1 101 ? -33.071 11.312 -43.931 1.00 69.88 ? 101 TRP B CB 1 ATOM 3791 C CG . TRP B 1 101 ? -34.351 11.509 -44.699 1.00 70.68 ? 101 TRP B CG 1 ATOM 3792 C CD1 . TRP B 1 101 ? -34.728 10.903 -45.861 1.00 73.73 ? 101 TRP B CD1 1 ATOM 3793 C CD2 . TRP B 1 101 ? -35.456 12.341 -44.305 1.00 70.33 ? 101 TRP B CD2 1 ATOM 3794 N NE1 . TRP B 1 101 ? -36.001 11.300 -46.214 1.00 73.22 ? 101 TRP B NE1 1 ATOM 3795 C CE2 . TRP B 1 101 ? -36.467 12.189 -45.281 1.00 74.09 ? 101 TRP B CE2 1 ATOM 3796 C CE3 . TRP B 1 101 ? -35.689 13.211 -43.219 1.00 71.47 ? 101 TRP B CE3 1 ATOM 3797 C CZ2 . TRP B 1 101 ? -37.680 12.890 -45.221 1.00 72.93 ? 101 TRP B CZ2 1 ATOM 3798 C CZ3 . TRP B 1 101 ? -36.906 13.876 -43.140 1.00 72.62 ? 101 TRP B CZ3 1 ATOM 3799 C CH2 . TRP B 1 101 ? -37.878 13.724 -44.141 1.00 73.19 ? 101 TRP B CH2 1 ATOM 3800 N N . GLY B 1 102 ? -29.985 10.645 -43.150 1.00 77.53 ? 102 GLY B N 1 ATOM 3801 C CA . GLY B 1 102 ? -29.097 10.265 -42.063 1.00 77.17 ? 102 GLY B CA 1 ATOM 3802 C C . GLY B 1 102 ? -27.907 9.491 -42.559 1.00 81.36 ? 102 GLY B C 1 ATOM 3803 O O . GLY B 1 102 ? -26.895 9.419 -41.855 1.00 81.10 ? 102 GLY B O 1 ATOM 3804 N N . ASN B 1 103 ? -28.024 8.913 -43.779 1.00 78.81 ? 103 ASN B N 1 ATOM 3805 C CA . ASN B 1 103 ? -26.949 8.189 -44.478 1.00 79.17 ? 103 ASN B CA 1 ATOM 3806 C C . ASN B 1 103 ? -27.025 8.413 -46.019 1.00 84.12 ? 103 ASN B C 1 ATOM 3807 O O . ASN B 1 103 ? -26.568 7.591 -46.818 1.00 82.87 ? 103 ASN B O 1 ATOM 3808 C CB . ASN B 1 103 ? -26.844 6.711 -44.075 1.00 77.54 ? 103 ASN B CB 1 ATOM 3809 C CG . ASN B 1 103 ? -28.036 5.873 -44.429 1.00 92.91 ? 103 ASN B CG 1 ATOM 3810 O OD1 . ASN B 1 103 ? -28.214 5.476 -45.576 1.00 76.96 ? 103 ASN B OD1 1 ATOM 3811 N ND2 . ASN B 1 103 ? -28.841 5.525 -43.437 1.00 88.81 ? 103 ASN B ND2 1 ATOM 3812 N N . GLY B 1 104 ? -27.581 9.569 -46.386 1.00 81.67 ? 104 GLY B N 1 ATOM 3813 C CA . GLY B 1 104 ? -27.615 10.091 -47.743 1.00 81.35 ? 104 GLY B CA 1 ATOM 3814 C C . GLY B 1 104 ? -28.767 9.833 -48.677 1.00 85.62 ? 104 GLY B C 1 ATOM 3815 O O . GLY B 1 104 ? -28.694 10.299 -49.813 1.00 85.93 ? 104 GLY B O 1 ATOM 3816 N N . CYS B 1 105 ? -29.823 9.120 -48.256 1.00 82.13 ? 105 CYS B N 1 ATOM 3817 C CA . CYS B 1 105 ? -30.939 8.810 -49.163 1.00 81.41 ? 105 CYS B CA 1 ATOM 3818 C C . CYS B 1 105 ? -32.204 9.596 -48.895 1.00 83.82 ? 105 CYS B C 1 ATOM 3819 O O . CYS B 1 105 ? -32.625 9.716 -47.748 1.00 83.94 ? 105 CYS B O 1 ATOM 3820 C CB . CYS B 1 105 ? -31.231 7.316 -49.183 1.00 81.84 ? 105 CYS B CB 1 ATOM 3821 S SG . CYS B 1 105 ? -29.798 6.282 -49.567 1.00 85.90 ? 105 CYS B SG 1 ATOM 3822 N N . GLY B 1 106 ? -32.849 10.040 -49.971 1.00 78.24 ? 106 GLY B N 1 ATOM 3823 C CA . GLY B 1 106 ? -34.117 10.762 -49.898 1.00 76.74 ? 106 GLY B CA 1 ATOM 3824 C C . GLY B 1 106 ? -35.261 9.881 -49.434 1.00 77.23 ? 106 GLY B C 1 ATOM 3825 O O . GLY B 1 106 ? -36.206 10.360 -48.804 1.00 75.96 ? 106 GLY B O 1 ATOM 3826 N N . LEU B 1 107 ? -35.160 8.578 -49.739 1.00 72.39 ? 107 LEU B N 1 ATOM 3827 C CA . LEU B 1 107 ? -36.120 7.544 -49.356 1.00 72.02 ? 107 LEU B CA 1 ATOM 3828 C C . LEU B 1 107 ? -35.506 6.645 -48.278 1.00 74.91 ? 107 LEU B C 1 ATOM 3829 O O . LEU B 1 107 ? -34.280 6.535 -48.203 1.00 75.29 ? 107 LEU B O 1 ATOM 3830 C CB . LEU B 1 107 ? -36.468 6.663 -50.562 1.00 71.88 ? 107 LEU B CB 1 ATOM 3831 C CG . LEU B 1 107 ? -37.054 7.310 -51.791 1.00 75.24 ? 107 LEU B CG 1 ATOM 3832 C CD1 . LEU B 1 107 ? -35.963 7.609 -52.813 1.00 75.21 ? 107 LEU B CD1 1 ATOM 3833 C CD2 . LEU B 1 107 ? -38.084 6.366 -52.412 1.00 75.27 ? 107 LEU B CD2 1 ATOM 3834 N N . PHE B 1 108 ? -36.355 5.994 -47.470 1.00 69.21 ? 108 PHE B N 1 ATOM 3835 C CA . PHE B 1 108 ? -35.935 5.082 -46.411 1.00 67.66 ? 108 PHE B CA 1 ATOM 3836 C C . PHE B 1 108 ? -36.202 3.640 -46.828 1.00 70.08 ? 108 PHE B C 1 ATOM 3837 O O . PHE B 1 108 ? -37.369 3.255 -47.050 1.00 69.23 ? 108 PHE B O 1 ATOM 3838 C CB . PHE B 1 108 ? -36.715 5.353 -45.135 1.00 68.82 ? 108 PHE B CB 1 ATOM 3839 C CG . PHE B 1 108 ? -36.453 6.660 -44.452 1.00 69.82 ? 108 PHE B CG 1 ATOM 3840 C CD1 . PHE B 1 108 ? -35.451 6.769 -43.491 1.00 72.08 ? 108 PHE B CD1 1 ATOM 3841 C CD2 . PHE B 1 108 ? -37.290 7.754 -44.669 1.00 71.52 ? 108 PHE B CD2 1 ATOM 3842 C CE1 . PHE B 1 108 ? -35.251 7.969 -42.802 1.00 73.10 ? 108 PHE B CE1 1 ATOM 3843 C CE2 . PHE B 1 108 ? -37.098 8.951 -43.973 1.00 73.89 ? 108 PHE B CE2 1 ATOM 3844 C CZ . PHE B 1 108 ? -36.083 9.051 -43.042 1.00 71.91 ? 108 PHE B CZ 1 ATOM 3845 N N . GLY B 1 109 ? -35.140 2.837 -46.868 1.00 64.92 ? 109 GLY B N 1 ATOM 3846 C CA . GLY B 1 109 ? -35.286 1.437 -47.247 1.00 63.77 ? 109 GLY B CA 1 ATOM 3847 C C . GLY B 1 109 ? -33.998 0.665 -47.335 1.00 63.93 ? 109 GLY B C 1 ATOM 3848 O O . GLY B 1 109 ? -32.978 1.093 -46.812 1.00 62.24 ? 109 GLY B O 1 ATOM 3849 N N . LYS B 1 110 ? -34.053 -0.479 -47.996 1.00 60.02 ? 110 LYS B N 1 ATOM 3850 C CA . LYS B 1 110 ? -32.913 -1.358 -48.142 1.00 59.82 ? 110 LYS B CA 1 ATOM 3851 C C . LYS B 1 110 ? -32.108 -1.058 -49.424 1.00 64.07 ? 110 LYS B C 1 ATOM 3852 O O . LYS B 1 110 ? -32.490 -1.464 -50.534 1.00 61.56 ? 110 LYS B O 1 ATOM 3853 C CB . LYS B 1 110 ? -33.346 -2.842 -48.038 1.00 61.57 ? 110 LYS B CB 1 ATOM 3854 C CG . LYS B 1 110 ? -33.991 -3.257 -46.710 1.00 61.18 ? 110 LYS B CG 1 ATOM 3855 C CD . LYS B 1 110 ? -32.994 -3.423 -45.580 1.00 69.84 ? 110 LYS B CD 1 ATOM 3856 C CE . LYS B 1 110 ? -33.585 -4.173 -44.417 1.00 84.56 ? 110 LYS B CE 1 ATOM 3857 N NZ . LYS B 1 110 ? -32.683 -4.195 -43.232 1.00 94.96 ? 110 LYS B NZ 1 ATOM 3858 N N . GLY B 1 111 ? -31.013 -0.321 -49.239 1.00 62.12 ? 111 GLY B N 1 ATOM 3859 C CA . GLY B 1 111 ? -30.095 0.037 -50.307 1.00 62.48 ? 111 GLY B CA 1 ATOM 3860 C C . GLY B 1 111 ? -29.120 -1.078 -50.592 1.00 68.73 ? 111 GLY B C 1 ATOM 3861 O O . GLY B 1 111 ? -28.484 -1.586 -49.679 1.00 68.84 ? 111 GLY B O 1 ATOM 3862 N N . GLY B 1 112 ? -29.039 -1.478 -51.853 1.00 66.85 ? 112 GLY B N 1 ATOM 3863 C CA . GLY B 1 112 ? -28.158 -2.541 -52.314 1.00 66.91 ? 112 GLY B CA 1 ATOM 3864 C C . GLY B 1 112 ? -26.687 -2.199 -52.192 1.00 71.03 ? 112 GLY B C 1 ATOM 3865 O O . GLY B 1 112 ? -26.269 -1.086 -52.516 1.00 70.11 ? 112 GLY B O 1 ATOM 3866 N N . ILE B 1 113 ? -25.902 -3.160 -51.696 1.00 67.67 ? 113 ILE B N 1 ATOM 3867 C CA . ILE B 1 113 ? -24.464 -3.040 -51.498 1.00 66.37 ? 113 ILE B CA 1 ATOM 3868 C C . ILE B 1 113 ? -23.782 -4.183 -52.236 1.00 73.81 ? 113 ILE B C 1 ATOM 3869 O O . ILE B 1 113 ? -24.412 -5.210 -52.502 1.00 74.59 ? 113 ILE B O 1 ATOM 3870 C CB . ILE B 1 113 ? -24.127 -3.016 -49.981 1.00 67.70 ? 113 ILE B CB 1 ATOM 3871 C CG1 . ILE B 1 113 ? -22.838 -2.223 -49.708 1.00 67.41 ? 113 ILE B CG1 1 ATOM 3872 C CG2 . ILE B 1 113 ? -24.103 -4.410 -49.364 1.00 66.91 ? 113 ILE B CG2 1 ATOM 3873 C CD1 . ILE B 1 113 ? -22.268 -2.289 -48.226 1.00 72.87 ? 113 ILE B CD1 1 ATOM 3874 N N . VAL B 1 114 ? -22.503 -3.994 -52.585 1.00 70.77 ? 114 VAL B N 1 ATOM 3875 C CA . VAL B 1 114 ? -21.667 -5.003 -53.236 1.00 69.41 ? 114 VAL B CA 1 ATOM 3876 C C . VAL B 1 114 ? -20.210 -4.805 -52.771 1.00 70.99 ? 114 VAL B C 1 ATOM 3877 O O . VAL B 1 114 ? -19.689 -3.682 -52.779 1.00 68.25 ? 114 VAL B O 1 ATOM 3878 C CB . VAL B 1 114 ? -21.848 -5.128 -54.784 1.00 72.26 ? 114 VAL B CB 1 ATOM 3879 C CG1 . VAL B 1 114 ? -21.451 -3.855 -55.512 1.00 72.19 ? 114 VAL B CG1 1 ATOM 3880 C CG2 . VAL B 1 114 ? -21.088 -6.327 -55.342 1.00 71.86 ? 114 VAL B CG2 1 ATOM 3881 N N . THR B 1 115 ? -19.589 -5.902 -52.315 1.00 67.50 ? 115 THR B N 1 ATOM 3882 C CA . THR B 1 115 ? -18.208 -5.891 -51.845 1.00 66.85 ? 115 THR B CA 1 ATOM 3883 C C . THR B 1 115 ? -17.393 -6.947 -52.626 1.00 68.90 ? 115 THR B C 1 ATOM 3884 O O . THR B 1 115 ? -17.855 -8.084 -52.783 1.00 66.65 ? 115 THR B O 1 ATOM 3885 C CB . THR B 1 115 ? -18.165 -6.107 -50.311 1.00 72.91 ? 115 THR B CB 1 ATOM 3886 O OG1 . THR B 1 115 ? -19.194 -5.353 -49.636 1.00 73.67 ? 115 THR B OG1 1 ATOM 3887 C CG2 . THR B 1 115 ? -16.795 -5.809 -49.721 1.00 64.79 ? 115 THR B CG2 1 ATOM 3888 N N . CYS B 1 116 ? -16.192 -6.547 -53.118 1.00 66.27 ? 116 CYS B N 1 ATOM 3889 C CA . CYS B 1 116 ? -15.224 -7.403 -53.816 1.00 66.55 ? 116 CYS B CA 1 ATOM 3890 C C . CYS B 1 116 ? -13.860 -7.272 -53.178 1.00 69.21 ? 116 CYS B C 1 ATOM 3891 O O . CYS B 1 116 ? -13.463 -6.168 -52.797 1.00 68.04 ? 116 CYS B O 1 ATOM 3892 C CB . CYS B 1 116 ? -15.148 -7.091 -55.301 1.00 67.61 ? 116 CYS B CB 1 ATOM 3893 S SG . CYS B 1 116 ? -16.690 -7.354 -56.187 1.00 72.40 ? 116 CYS B SG 1 ATOM 3894 N N . ALA B 1 117 ? -13.134 -8.395 -53.085 1.00 64.88 ? 117 ALA B N 1 ATOM 3895 C CA . ALA B 1 117 ? -11.778 -8.450 -52.541 1.00 63.41 ? 117 ALA B CA 1 ATOM 3896 C C . ALA B 1 117 ? -10.949 -9.453 -53.326 1.00 65.55 ? 117 ALA B C 1 ATOM 3897 O O . ALA B 1 117 ? -11.508 -10.370 -53.933 1.00 66.16 ? 117 ALA B O 1 ATOM 3898 C CB . ALA B 1 117 ? -11.815 -8.815 -51.079 1.00 63.95 ? 117 ALA B CB 1 ATOM 3899 N N . LYS B 1 118 ? -9.631 -9.241 -53.383 1.00 59.48 ? 118 LYS B N 1 ATOM 3900 C CA . LYS B 1 118 ? -8.731 -10.102 -54.151 1.00 58.64 ? 118 LYS B CA 1 ATOM 3901 C C . LYS B 1 118 ? -8.202 -11.254 -53.331 1.00 61.85 ? 118 LYS B C 1 ATOM 3902 O O . LYS B 1 118 ? -7.455 -11.059 -52.352 1.00 60.62 ? 118 LYS B O 1 ATOM 3903 C CB . LYS B 1 118 ? -7.584 -9.312 -54.806 1.00 61.33 ? 118 LYS B CB 1 ATOM 3904 C CG . LYS B 1 118 ? -7.127 -9.926 -56.119 1.00 73.42 ? 118 LYS B CG 1 ATOM 3905 C CD . LYS B 1 118 ? -5.760 -9.407 -56.531 1.00 87.19 ? 118 LYS B CD 1 ATOM 3906 C CE . LYS B 1 118 ? -5.197 -10.194 -57.693 1.00 97.54 ? 118 LYS B CE 1 ATOM 3907 N NZ . LYS B 1 118 ? -3.936 -9.600 -58.217 1.00 96.64 ? 118 LYS B NZ 1 ATOM 3908 N N . PHE B 1 119 ? -8.592 -12.465 -53.765 1.00 58.76 ? 119 PHE B N 1 ATOM 3909 C CA . PHE B 1 119 ? -8.221 -13.734 -53.153 1.00 58.71 ? 119 PHE B CA 1 ATOM 3910 C C . PHE B 1 119 ? -6.851 -14.189 -53.640 1.00 61.48 ? 119 PHE B C 1 ATOM 3911 O O . PHE B 1 119 ? -6.678 -14.547 -54.809 1.00 59.96 ? 119 PHE B O 1 ATOM 3912 C CB . PHE B 1 119 ? -9.274 -14.791 -53.457 1.00 60.90 ? 119 PHE B CB 1 ATOM 3913 C CG . PHE B 1 119 ? -9.062 -16.107 -52.754 1.00 63.29 ? 119 PHE B CG 1 ATOM 3914 C CD1 . PHE B 1 119 ? -8.237 -17.087 -53.303 1.00 67.57 ? 119 PHE B CD1 1 ATOM 3915 C CD2 . PHE B 1 119 ? -9.727 -16.393 -51.568 1.00 64.56 ? 119 PHE B CD2 1 ATOM 3916 C CE1 . PHE B 1 119 ? -8.069 -18.320 -52.662 1.00 68.36 ? 119 PHE B CE1 1 ATOM 3917 C CE2 . PHE B 1 119 ? -9.563 -17.626 -50.935 1.00 67.03 ? 119 PHE B CE2 1 ATOM 3918 C CZ . PHE B 1 119 ? -8.739 -18.583 -51.486 1.00 66.01 ? 119 PHE B CZ 1 ATOM 3919 N N . THR B 1 120 ? -5.890 -14.188 -52.710 1.00 58.95 ? 120 THR B N 1 ATOM 3920 C CA . THR B 1 120 ? -4.497 -14.560 -52.926 1.00 59.39 ? 120 THR B CA 1 ATOM 3921 C C . THR B 1 120 ? -4.165 -15.795 -52.072 1.00 62.71 ? 120 THR B C 1 ATOM 3922 O O . THR B 1 120 ? -4.273 -15.744 -50.847 1.00 62.14 ? 120 THR B O 1 ATOM 3923 C CB . THR B 1 120 ? -3.588 -13.373 -52.574 1.00 74.10 ? 120 THR B CB 1 ATOM 3924 O OG1 . THR B 1 120 ? -4.268 -12.106 -52.774 1.00 75.94 ? 120 THR B OG1 1 ATOM 3925 C CG2 . THR B 1 120 ? -2.265 -13.431 -53.316 1.00 73.94 ? 120 THR B CG2 1 ATOM 3926 N N . CYS B 1 121 ? -3.777 -16.903 -52.708 1.00 58.39 ? 121 CYS B N 1 ATOM 3927 C CA . CYS B 1 121 ? -3.440 -18.096 -51.950 1.00 57.15 ? 121 CYS B CA 1 ATOM 3928 C C . CYS B 1 121 ? -2.015 -18.032 -51.443 1.00 60.01 ? 121 CYS B C 1 ATOM 3929 O O . CYS B 1 121 ? -1.091 -17.711 -52.196 1.00 60.33 ? 121 CYS B O 1 ATOM 3930 C CB . CYS B 1 121 ? -3.690 -19.363 -52.758 1.00 57.30 ? 121 CYS B CB 1 ATOM 3931 S SG . CYS B 1 121 ? -3.708 -20.875 -51.757 1.00 61.16 ? 121 CYS B SG 1 ATOM 3932 N N . LYS B 1 122 ? -1.838 -18.350 -50.162 1.00 54.84 ? 122 LYS B N 1 ATOM 3933 C CA . LYS B 1 122 ? -0.551 -18.349 -49.470 1.00 53.67 ? 122 LYS B CA 1 ATOM 3934 C C . LYS B 1 122 ? 0.065 -19.763 -49.298 1.00 56.02 ? 122 LYS B C 1 ATOM 3935 O O . LYS B 1 122 ? 1.288 -19.881 -49.282 1.00 55.04 ? 122 LYS B O 1 ATOM 3936 C CB . LYS B 1 122 ? -0.713 -17.669 -48.108 1.00 56.33 ? 122 LYS B CB 1 ATOM 3937 C CG . LYS B 1 122 ? -0.805 -16.145 -48.196 1.00 72.86 ? 122 LYS B CG 1 ATOM 3938 C CD . LYS B 1 122 ? -1.328 -15.513 -46.894 1.00 81.20 ? 122 LYS B CD 1 ATOM 3939 C CE . LYS B 1 122 ? -0.325 -15.380 -45.765 1.00 81.09 ? 122 LYS B CE 1 ATOM 3940 N NZ . LYS B 1 122 ? -0.954 -14.807 -44.536 1.00 74.60 ? 122 LYS B NZ 1 ATOM 3941 N N . LYS B 1 123 ? -0.773 -20.832 -49.206 1.00 50.98 ? 123 LYS B N 1 ATOM 3942 C CA . LYS B 1 123 ? -0.290 -22.198 -48.981 1.00 49.25 ? 123 LYS B CA 1 ATOM 3943 C C . LYS B 1 123 ? -1.119 -23.241 -49.755 1.00 50.92 ? 123 LYS B C 1 ATOM 3944 O O . LYS B 1 123 ? -2.334 -23.113 -49.768 1.00 50.44 ? 123 LYS B O 1 ATOM 3945 C CB . LYS B 1 123 ? -0.341 -22.452 -47.457 1.00 51.47 ? 123 LYS B CB 1 ATOM 3946 C CG . LYS B 1 123 ? 0.728 -23.386 -46.943 1.00 70.34 ? 123 LYS B CG 1 ATOM 3947 C CD . LYS B 1 123 ? 1.342 -23.019 -45.597 1.00 76.81 ? 123 LYS B CD 1 ATOM 3948 C CE . LYS B 1 123 ? 2.417 -24.059 -45.317 1.00 86.50 ? 123 LYS B CE 1 ATOM 3949 N NZ . LYS B 1 123 ? 3.142 -23.850 -44.030 1.00 97.09 ? 123 LYS B NZ 1 ATOM 3950 N N . ASN B 1 124 ? -0.491 -24.264 -50.400 1.00 47.23 ? 124 ASN B N 1 ATOM 3951 C CA . ASN B 1 124 ? -1.266 -25.292 -51.152 1.00 46.65 ? 124 ASN B CA 1 ATOM 3952 C C . ASN B 1 124 ? -1.150 -26.738 -50.625 1.00 50.62 ? 124 ASN B C 1 ATOM 3953 O O . ASN B 1 124 ? -0.341 -27.052 -49.758 1.00 50.67 ? 124 ASN B O 1 ATOM 3954 C CB . ASN B 1 124 ? -0.889 -25.354 -52.643 1.00 43.71 ? 124 ASN B CB 1 ATOM 3955 C CG . ASN B 1 124 ? -0.798 -24.095 -53.463 1.00 83.39 ? 124 ASN B CG 1 ATOM 3956 O OD1 . ASN B 1 124 ? -0.272 -24.151 -54.579 1.00 80.81 ? 124 ASN B OD1 1 ATOM 3957 N ND2 . ASN B 1 124 ? -1.280 -22.940 -52.979 1.00 79.55 ? 124 ASN B ND2 1 ATOM 3958 N N . MET B 1 125 ? -1.933 -27.617 -51.241 1.00 46.48 ? 125 MET B N 1 ATOM 3959 C CA . MET B 1 125 ? -2.013 -29.061 -51.075 1.00 46.42 ? 125 MET B CA 1 ATOM 3960 C C . MET B 1 125 ? -2.120 -29.578 -52.490 1.00 54.62 ? 125 MET B C 1 ATOM 3961 O O . MET B 1 125 ? -2.837 -28.977 -53.315 1.00 54.50 ? 125 MET B O 1 ATOM 3962 C CB . MET B 1 125 ? -3.326 -29.496 -50.416 1.00 48.20 ? 125 MET B CB 1 ATOM 3963 C CG . MET B 1 125 ? -3.419 -29.215 -48.986 1.00 52.06 ? 125 MET B CG 1 ATOM 3964 S SD . MET B 1 125 ? -4.574 -30.394 -48.261 1.00 56.73 ? 125 MET B SD 1 ATOM 3965 C CE . MET B 1 125 ? -6.127 -29.677 -48.628 1.00 53.40 ? 125 MET B CE 1 ATOM 3966 N N . GLU B 1 126 ? -1.497 -30.736 -52.760 1.00 52.53 ? 126 GLU B N 1 ATOM 3967 C CA . GLU B 1 126 ? -1.615 -31.369 -54.066 1.00 52.77 ? 126 GLU B CA 1 ATOM 3968 C C . GLU B 1 126 ? -2.015 -32.785 -53.891 1.00 59.27 ? 126 GLU B C 1 ATOM 3969 O O . GLU B 1 126 ? -1.515 -33.472 -53.000 1.00 59.38 ? 126 GLU B O 1 ATOM 3970 C CB . GLU B 1 126 ? -0.327 -31.280 -54.867 1.00 54.14 ? 126 GLU B CB 1 ATOM 3971 C CG . GLU B 1 126 ? 0.038 -29.868 -55.286 1.00 63.51 ? 126 GLU B CG 1 ATOM 3972 C CD . GLU B 1 126 ? 0.658 -29.777 -56.664 1.00 92.22 ? 126 GLU B CD 1 ATOM 3973 O OE1 . GLU B 1 126 ? 0.591 -30.773 -57.423 1.00 72.31 ? 126 GLU B OE1 1 ATOM 3974 O OE2 . GLU B 1 126 ? 1.193 -28.693 -56.992 1.00 102.91 ? 126 GLU B OE2 1 ATOM 3975 N N . GLY B 1 127 ? -2.962 -33.202 -54.704 1.00 58.46 ? 127 GLY B N 1 ATOM 3976 C CA . GLY B 1 127 ? -3.446 -34.574 -54.695 1.00 59.64 ? 127 GLY B CA 1 ATOM 3977 C C . GLY B 1 127 ? -3.063 -35.227 -55.998 1.00 65.52 ? 127 GLY B C 1 ATOM 3978 O O . GLY B 1 127 ? -3.316 -34.640 -57.051 1.00 66.58 ? 127 GLY B O 1 ATOM 3979 N N . LYS B 1 128 ? -2.424 -36.405 -55.953 1.00 61.40 ? 128 LYS B N 1 ATOM 3980 C CA . LYS B 1 128 ? -2.008 -37.073 -57.183 1.00 61.09 ? 128 LYS B CA 1 ATOM 3981 C C . LYS B 1 128 ? -2.573 -38.456 -57.359 1.00 69.76 ? 128 LYS B C 1 ATOM 3982 O O . LYS B 1 128 ? -2.703 -39.197 -56.384 1.00 69.40 ? 128 LYS B O 1 ATOM 3983 C CB . LYS B 1 128 ? -0.493 -37.098 -57.304 1.00 61.19 ? 128 LYS B CB 1 ATOM 3984 C CG . LYS B 1 128 ? 0.036 -35.822 -57.910 1.00 58.81 ? 128 LYS B CG 1 ATOM 3985 C CD . LYS B 1 128 ? 1.099 -35.160 -57.057 1.00 60.26 ? 128 LYS B CD 1 ATOM 3986 C CE . LYS B 1 128 ? 2.130 -34.497 -57.944 1.00 53.35 ? 128 LYS B CE 1 ATOM 3987 N NZ . LYS B 1 128 ? 2.974 -33.528 -57.200 1.00 48.52 ? 128 LYS B NZ 1 ATOM 3988 N N . ILE B 1 129 ? -2.919 -38.810 -58.608 1.00 70.70 ? 129 ILE B N 1 ATOM 3989 C CA . ILE B 1 129 ? -3.382 -40.165 -58.894 1.00 72.84 ? 129 ILE B CA 1 ATOM 3990 C C . ILE B 1 129 ? -2.157 -41.031 -59.232 1.00 84.29 ? 129 ILE B C 1 ATOM 3991 O O . ILE B 1 129 ? -1.456 -40.776 -60.218 1.00 83.63 ? 129 ILE B O 1 ATOM 3992 C CB . ILE B 1 129 ? -4.549 -40.292 -59.898 1.00 75.15 ? 129 ILE B CB 1 ATOM 3993 C CG1 . ILE B 1 129 ? -5.784 -39.531 -59.391 1.00 74.97 ? 129 ILE B CG1 1 ATOM 3994 C CG2 . ILE B 1 129 ? -4.882 -41.779 -60.112 1.00 76.42 ? 129 ILE B CG2 1 ATOM 3995 C CD1 . ILE B 1 129 ? -6.958 -39.421 -60.367 1.00 81.18 ? 129 ILE B CD1 1 ATOM 3996 N N . VAL B 1 130 ? -1.895 -42.022 -58.360 1.00 86.21 ? 130 VAL B N 1 ATOM 3997 C CA . VAL B 1 130 ? -0.762 -42.940 -58.416 1.00 88.22 ? 130 VAL B CA 1 ATOM 3998 C C . VAL B 1 130 ? -1.244 -44.380 -58.658 1.00 95.91 ? 130 VAL B C 1 ATOM 3999 O O . VAL B 1 130 ? -1.878 -44.992 -57.782 1.00 94.87 ? 130 VAL B O 1 ATOM 4000 C CB . VAL B 1 130 ? 0.066 -42.815 -57.112 1.00 92.71 ? 130 VAL B CB 1 ATOM 4001 C CG1 . VAL B 1 130 ? 1.142 -43.894 -57.018 1.00 92.79 ? 130 VAL B CG1 1 ATOM 4002 C CG2 . VAL B 1 130 ? 0.677 -41.426 -56.984 1.00 92.61 ? 130 VAL B CG2 1 ATOM 4003 N N . GLN B 1 131 ? -0.925 -44.921 -59.849 1.00 94.92 ? 131 GLN B N 1 ATOM 4004 C CA . GLN B 1 131 ? -1.312 -46.282 -60.177 1.00 95.57 ? 131 GLN B CA 1 ATOM 4005 C C . GLN B 1 131 ? -0.168 -47.267 -59.925 1.00 101.47 ? 131 GLN B C 1 ATOM 4006 O O . GLN B 1 131 ? 0.997 -46.896 -60.126 1.00 100.88 ? 131 GLN B O 1 ATOM 4007 C CB . GLN B 1 131 ? -1.913 -46.391 -61.583 1.00 97.03 ? 131 GLN B CB 1 ATOM 4008 C CG . GLN B 1 131 ? -3.405 -45.990 -61.648 1.00 113.64 ? 131 GLN B CG 1 ATOM 4009 C CD . GLN B 1 131 ? -4.246 -46.344 -60.422 1.00 124.38 ? 131 GLN B CD 1 ATOM 4010 O OE1 . GLN B 1 131 ? -4.666 -45.458 -59.660 1.00 117.41 ? 131 GLN B OE1 1 ATOM 4011 N NE2 . GLN B 1 131 ? -4.523 -47.634 -60.215 1.00 107.43 ? 131 GLN B NE2 1 ATOM 4012 N N . PRO B 1 132 ? -0.483 -48.495 -59.408 1.00 99.47 ? 132 PRO B N 1 ATOM 4013 C CA . PRO B 1 132 ? 0.575 -49.457 -59.059 1.00 99.37 ? 132 PRO B CA 1 ATOM 4014 C C . PRO B 1 132 ? 1.565 -49.801 -60.166 1.00 103.56 ? 132 PRO B C 1 ATOM 4015 O O . PRO B 1 132 ? 2.742 -49.989 -59.876 1.00 103.19 ? 132 PRO B O 1 ATOM 4016 C CB . PRO B 1 132 ? -0.209 -50.694 -58.605 1.00 101.17 ? 132 PRO B CB 1 ATOM 4017 C CG . PRO B 1 132 ? -1.495 -50.184 -58.155 1.00 105.59 ? 132 PRO B CG 1 ATOM 4018 C CD . PRO B 1 132 ? -1.812 -49.056 -59.085 1.00 101.32 ? 132 PRO B CD 1 ATOM 4019 N N . GLU B 1 133 ? 1.094 -49.890 -61.422 1.00 100.11 ? 133 GLU B N 1 ATOM 4020 C CA . GLU B 1 133 ? 1.918 -50.225 -62.587 1.00 99.81 ? 133 GLU B CA 1 ATOM 4021 C C . GLU B 1 133 ? 3.160 -49.350 -62.790 1.00 105.91 ? 133 GLU B C 1 ATOM 4022 O O . GLU B 1 133 ? 4.170 -49.853 -63.305 1.00 106.32 ? 133 GLU B O 1 ATOM 4023 C CB . GLU B 1 133 ? 1.080 -50.225 -63.870 1.00 100.77 ? 133 GLU B CB 1 ATOM 4024 C CG . GLU B 1 133 ? 0.119 -49.056 -63.999 1.00 106.54 ? 133 GLU B CG 1 ATOM 4025 C CD . GLU B 1 133 ? -1.313 -49.439 -63.688 1.00 119.21 ? 133 GLU B CD 1 ATOM 4026 O OE1 . GLU B 1 133 ? -1.530 -50.230 -62.739 1.00 105.52 ? 133 GLU B OE1 1 ATOM 4027 O OE2 . GLU B 1 133 ? -2.216 -48.975 -64.420 1.00 109.73 ? 133 GLU B OE2 1 ATOM 4028 N N . ASN B 1 134 ? 3.089 -48.051 -62.399 1.00 102.57 ? 134 ASN B N 1 ATOM 4029 C CA . ASN B 1 134 ? 4.177 -47.084 -62.617 1.00 102.18 ? 134 ASN B CA 1 ATOM 4030 C C . ASN B 1 134 ? 4.888 -46.661 -61.311 1.00 104.66 ? 134 ASN B C 1 ATOM 4031 O O . ASN B 1 134 ? 5.522 -45.599 -61.240 1.00 103.93 ? 134 ASN B O 1 ATOM 4032 C CB . ASN B 1 134 ? 3.668 -45.878 -63.435 1.00 103.85 ? 134 ASN B CB 1 ATOM 4033 C CG . ASN B 1 134 ? 2.502 -46.189 -64.365 1.00 118.90 ? 134 ASN B CG 1 ATOM 4034 O OD1 . ASN B 1 134 ? 1.396 -45.660 -64.205 1.00 116.37 ? 134 ASN B OD1 1 ATOM 4035 N ND2 . ASN B 1 134 ? 2.701 -47.089 -65.324 1.00 104.07 ? 134 ASN B ND2 1 ATOM 4036 N N . LEU B 1 135 ? 4.814 -47.543 -60.301 1.00 100.52 ? 135 LEU B N 1 ATOM 4037 C CA . LEU B 1 135 ? 5.465 -47.448 -58.989 1.00 99.73 ? 135 LEU B CA 1 ATOM 4038 C C . LEU B 1 135 ? 6.830 -48.137 -59.128 1.00 101.59 ? 135 LEU B C 1 ATOM 4039 O O . LEU B 1 135 ? 6.865 -49.339 -59.387 1.00 102.29 ? 135 LEU B O 1 ATOM 4040 C CB . LEU B 1 135 ? 4.610 -48.206 -57.960 1.00 99.88 ? 135 LEU B CB 1 ATOM 4041 C CG . LEU B 1 135 ? 4.592 -47.711 -56.523 1.00 105.02 ? 135 LEU B CG 1 ATOM 4042 C CD1 . LEU B 1 135 ? 3.462 -48.352 -55.749 1.00 105.41 ? 135 LEU B CD1 1 ATOM 4043 C CD2 . LEU B 1 135 ? 5.886 -48.005 -55.823 1.00 107.09 ? 135 LEU B CD2 1 ATOM 4044 N N . GLU B 1 136 ? 7.940 -47.397 -58.970 1.00 95.58 ? 136 GLU B N 1 ATOM 4045 C CA . GLU B 1 136 ? 9.292 -47.942 -59.123 1.00 94.92 ? 136 GLU B CA 1 ATOM 4046 C C . GLU B 1 136 ? 10.037 -48.152 -57.785 1.00 97.04 ? 136 GLU B C 1 ATOM 4047 O O . GLU B 1 136 ? 9.965 -47.309 -56.886 1.00 96.51 ? 136 GLU B O 1 ATOM 4048 C CB . GLU B 1 136 ? 10.107 -47.044 -60.071 1.00 96.60 ? 136 GLU B CB 1 ATOM 4049 C CG . GLU B 1 136 ? 11.471 -47.582 -60.476 1.00 109.34 ? 136 GLU B CG 1 ATOM 4050 C CD . GLU B 1 136 ? 12.329 -46.580 -61.226 1.00 130.71 ? 136 GLU B CD 1 ATOM 4051 O OE1 . GLU B 1 136 ? 12.183 -46.483 -62.466 1.00 117.26 ? 136 GLU B OE1 1 ATOM 4052 O OE2 . GLU B 1 136 ? 13.144 -45.885 -60.576 1.00 127.33 ? 136 GLU B OE2 1 ATOM 4053 N N . TYR B 1 137 ? 10.795 -49.264 -57.686 1.00 91.62 ? 137 TYR B N 1 ATOM 4054 C CA . TYR B 1 137 ? 11.609 -49.585 -56.507 1.00 89.63 ? 137 TYR B CA 1 ATOM 4055 C C . TYR B 1 137 ? 13.110 -49.529 -56.833 1.00 90.88 ? 137 TYR B C 1 ATOM 4056 O O . TYR B 1 137 ? 13.504 -49.875 -57.940 1.00 89.89 ? 137 TYR B O 1 ATOM 4057 C CB . TYR B 1 137 ? 11.222 -50.949 -55.922 1.00 89.31 ? 137 TYR B CB 1 ATOM 4058 C CG . TYR B 1 137 ? 9.740 -51.094 -55.658 1.00 88.79 ? 137 TYR B CG 1 ATOM 4059 C CD1 . TYR B 1 137 ? 9.168 -50.606 -54.486 1.00 89.12 ? 137 TYR B CD1 1 ATOM 4060 C CD2 . TYR B 1 137 ? 8.906 -51.720 -56.583 1.00 90.14 ? 137 TYR B CD2 1 ATOM 4061 C CE1 . TYR B 1 137 ? 7.803 -50.747 -54.235 1.00 90.01 ? 137 TYR B CE1 1 ATOM 4062 C CE2 . TYR B 1 137 ? 7.539 -51.858 -56.349 1.00 90.20 ? 137 TYR B CE2 1 ATOM 4063 C CZ . TYR B 1 137 ? 6.990 -51.375 -55.173 1.00 96.43 ? 137 TYR B CZ 1 ATOM 4064 O OH . TYR B 1 137 ? 5.640 -51.526 -54.959 1.00 94.36 ? 137 TYR B OH 1 ATOM 4065 N N . THR B 1 138 ? 13.929 -49.073 -55.876 1.00 86.75 ? 138 THR B N 1 ATOM 4066 C CA . THR B 1 138 ? 15.372 -48.953 -56.038 1.00 86.98 ? 138 THR B CA 1 ATOM 4067 C C . THR B 1 138 ? 16.091 -49.774 -54.966 1.00 90.60 ? 138 THR B C 1 ATOM 4068 O O . THR B 1 138 ? 16.118 -49.380 -53.794 1.00 90.41 ? 138 THR B O 1 ATOM 4069 C CB . THR B 1 138 ? 15.791 -47.477 -56.071 1.00 101.45 ? 138 THR B CB 1 ATOM 4070 O OG1 . THR B 1 138 ? 15.129 -46.835 -57.159 1.00 105.98 ? 138 THR B OG1 1 ATOM 4071 C CG2 . THR B 1 138 ? 17.305 -47.277 -56.186 1.00 99.94 ? 138 THR B CG2 1 ATOM 4072 N N . ILE B 1 139 ? 16.685 -50.913 -55.397 1.00 84.81 ? 139 ILE B N 1 ATOM 4073 C CA . ILE B 1 139 ? 17.432 -51.865 -54.576 1.00 82.54 ? 139 ILE B CA 1 ATOM 4074 C C . ILE B 1 139 ? 18.928 -51.704 -54.837 1.00 79.78 ? 139 ILE B C 1 ATOM 4075 O O . ILE B 1 139 ? 19.330 -51.532 -55.987 1.00 78.67 ? 139 ILE B O 1 ATOM 4076 C CB . ILE B 1 139 ? 16.934 -53.311 -54.880 1.00 86.09 ? 139 ILE B CB 1 ATOM 4077 C CG1 . ILE B 1 139 ? 15.469 -53.498 -54.407 1.00 86.33 ? 139 ILE B CG1 1 ATOM 4078 C CG2 . ILE B 1 139 ? 17.867 -54.393 -54.309 1.00 87.16 ? 139 ILE B CG2 1 ATOM 4079 C CD1 . ILE B 1 139 ? 14.742 -54.686 -55.048 1.00 90.63 ? 139 ILE B CD1 1 ATOM 4080 N N . VAL B 1 140 ? 19.739 -51.760 -53.770 1.00 71.92 ? 140 VAL B N 1 ATOM 4081 C CA . VAL B 1 140 ? 21.198 -51.697 -53.847 1.00 69.91 ? 140 VAL B CA 1 ATOM 4082 C C . VAL B 1 140 ? 21.804 -53.031 -53.387 1.00 73.07 ? 140 VAL B C 1 ATOM 4083 O O . VAL B 1 140 ? 21.623 -53.427 -52.229 1.00 72.92 ? 140 VAL B O 1 ATOM 4084 C CB . VAL B 1 140 ? 21.788 -50.473 -53.103 1.00 72.67 ? 140 VAL B CB 1 ATOM 4085 C CG1 . VAL B 1 140 ? 23.303 -50.561 -53.002 1.00 72.52 ? 140 VAL B CG1 1 ATOM 4086 C CG2 . VAL B 1 140 ? 21.394 -49.196 -53.807 1.00 72.43 ? 140 VAL B CG2 1 ATOM 4087 N N . ILE B 1 141 ? 22.515 -53.725 -54.293 1.00 68.47 ? 141 ILE B N 1 ATOM 4088 C CA . ILE B 1 141 ? 23.149 -55.001 -53.950 1.00 67.53 ? 141 ILE B CA 1 ATOM 4089 C C . ILE B 1 141 ? 24.636 -54.786 -53.731 1.00 70.71 ? 141 ILE B C 1 ATOM 4090 O O . ILE B 1 141 ? 25.334 -54.393 -54.660 1.00 70.85 ? 141 ILE B O 1 ATOM 4091 C CB . ILE B 1 141 ? 22.870 -56.124 -54.971 1.00 69.95 ? 141 ILE B CB 1 ATOM 4092 C CG1 . ILE B 1 141 ? 21.420 -56.136 -55.438 1.00 69.54 ? 141 ILE B CG1 1 ATOM 4093 C CG2 . ILE B 1 141 ? 23.272 -57.464 -54.398 1.00 70.86 ? 141 ILE B CG2 1 ATOM 4094 C CD1 . ILE B 1 141 ? 21.258 -55.806 -56.801 1.00 66.15 ? 141 ILE B CD1 1 ATOM 4095 N N . THR B 1 142 ? 25.110 -55.019 -52.512 1.00 65.96 ? 142 THR B N 1 ATOM 4096 C CA . THR B 1 142 ? 26.508 -54.836 -52.192 1.00 66.61 ? 142 THR B CA 1 ATOM 4097 C C . THR B 1 142 ? 27.169 -56.151 -51.810 1.00 74.94 ? 142 THR B C 1 ATOM 4098 O O . THR B 1 142 ? 26.893 -56.679 -50.732 1.00 75.66 ? 142 THR B O 1 ATOM 4099 C CB . THR B 1 142 ? 26.682 -53.764 -51.120 1.00 73.70 ? 142 THR B CB 1 ATOM 4100 O OG1 . THR B 1 142 ? 25.962 -52.602 -51.511 1.00 75.77 ? 142 THR B OG1 1 ATOM 4101 C CG2 . THR B 1 142 ? 28.154 -53.419 -50.861 1.00 69.64 ? 142 THR B CG2 1 ATOM 4102 N N . PRO B 1 143 ? 28.086 -56.691 -52.640 1.00 73.21 ? 143 PRO B N 1 ATOM 4103 C CA . PRO B 1 143 ? 28.776 -57.923 -52.237 1.00 73.51 ? 143 PRO B CA 1 ATOM 4104 C C . PRO B 1 143 ? 29.756 -57.693 -51.085 1.00 79.11 ? 143 PRO B C 1 ATOM 4105 O O . PRO B 1 143 ? 30.251 -56.560 -50.875 1.00 77.59 ? 143 PRO B O 1 ATOM 4106 C CB . PRO B 1 143 ? 29.488 -58.357 -53.519 1.00 74.81 ? 143 PRO B CB 1 ATOM 4107 C CG . PRO B 1 143 ? 29.691 -57.122 -54.274 1.00 78.24 ? 143 PRO B CG 1 ATOM 4108 C CD . PRO B 1 143 ? 28.548 -56.223 -53.964 1.00 73.88 ? 143 PRO B CD 1 ATOM 4109 N N . HIS B 1 144 ? 30.003 -58.787 -50.328 1.00 77.26 ? 144 HIS B N 1 ATOM 4110 C CA . HIS B 1 144 ? 30.945 -58.854 -49.210 1.00 77.77 ? 144 HIS B CA 1 ATOM 4111 C C . HIS B 1 144 ? 32.341 -59.178 -49.798 1.00 81.26 ? 144 HIS B C 1 ATOM 4112 O O . HIS B 1 144 ? 32.773 -60.328 -49.816 1.00 80.99 ? 144 HIS B O 1 ATOM 4113 C CB . HIS B 1 144 ? 30.496 -59.925 -48.201 1.00 79.01 ? 144 HIS B CB 1 ATOM 4114 C CG . HIS B 1 144 ? 29.673 -59.413 -47.063 1.00 82.24 ? 144 HIS B CG 1 ATOM 4115 N ND1 . HIS B 1 144 ? 30.211 -59.261 -45.791 1.00 83.74 ? 144 HIS B ND1 1 ATOM 4116 C CD2 . HIS B 1 144 ? 28.363 -59.083 -47.025 1.00 83.50 ? 144 HIS B CD2 1 ATOM 4117 C CE1 . HIS B 1 144 ? 29.216 -58.840 -45.029 1.00 82.77 ? 144 HIS B CE1 1 ATOM 4118 N NE2 . HIS B 1 144 ? 28.088 -58.708 -45.729 1.00 83.12 ? 144 HIS B NE2 1 ATOM 4119 N N . SER B 1 145 ? 32.961 -58.158 -50.399 1.00 77.11 ? 145 SER B N 1 ATOM 4120 C CA . SER B 1 145 ? 34.290 -58.113 -51.000 1.00 75.59 ? 145 SER B CA 1 ATOM 4121 C C . SER B 1 145 ? 34.881 -57.240 -49.938 1.00 76.37 ? 145 SER B C 1 ATOM 4122 O O . SER B 1 145 ? 34.295 -56.200 -49.680 1.00 79.06 ? 145 SER B O 1 ATOM 4123 C CB . SER B 1 145 ? 34.239 -57.345 -52.320 1.00 80.52 ? 145 SER B CB 1 ATOM 4124 O OG . SER B 1 145 ? 33.924 -55.967 -52.152 1.00 93.54 ? 145 SER B OG 1 ATOM 4125 N N . GLY B 1 146 ? 35.786 -57.748 -49.143 1.00 68.88 ? 146 GLY B N 1 ATOM 4126 C CA . GLY B 1 146 ? 36.388 -57.042 -48.011 1.00 66.92 ? 146 GLY B CA 1 ATOM 4127 C C . GLY B 1 146 ? 36.922 -55.648 -48.257 1.00 65.87 ? 146 GLY B C 1 ATOM 4128 O O . GLY B 1 146 ? 37.674 -55.138 -47.424 1.00 64.63 ? 146 GLY B O 1 ATOM 4129 N N . GLU B 1 147 ? 36.526 -55.012 -49.383 1.00 60.54 ? 147 GLU B N 1 ATOM 4130 C CA . GLU B 1 147 ? 36.914 -53.659 -49.762 1.00 60.42 ? 147 GLU B CA 1 ATOM 4131 C C . GLU B 1 147 ? 36.996 -52.735 -48.558 1.00 65.99 ? 147 GLU B C 1 ATOM 4132 O O . GLU B 1 147 ? 35.996 -52.504 -47.876 1.00 64.71 ? 147 GLU B O 1 ATOM 4133 C CB . GLU B 1 147 ? 36.022 -53.071 -50.870 1.00 61.46 ? 147 GLU B CB 1 ATOM 4134 C CG . GLU B 1 147 ? 36.729 -52.017 -51.730 1.00 70.16 ? 147 GLU B CG 1 ATOM 4135 C CD . GLU B 1 147 ? 37.343 -50.828 -51.007 1.00 94.76 ? 147 GLU B CD 1 ATOM 4136 O OE1 . GLU B 1 147 ? 36.576 -49.950 -50.547 1.00 104.68 ? 147 GLU B OE1 1 ATOM 4137 O OE2 . GLU B 1 147 ? 38.579 -50.832 -50.802 1.00 78.12 ? 147 GLU B OE2 1 ATOM 4138 N N . GLU B 1 148 ? 38.230 -52.270 -48.292 1.00 64.76 ? 148 GLU B N 1 ATOM 4139 C CA . GLU B 1 148 ? 38.655 -51.380 -47.222 1.00 65.54 ? 148 GLU B CA 1 ATOM 4140 C C . GLU B 1 148 ? 37.554 -50.413 -46.694 1.00 71.60 ? 148 GLU B C 1 ATOM 4141 O O . GLU B 1 148 ? 37.387 -50.320 -45.466 1.00 72.65 ? 148 GLU B O 1 ATOM 4142 C CB . GLU B 1 148 ? 39.906 -50.614 -47.675 1.00 66.93 ? 148 GLU B CB 1 ATOM 4143 C CG . GLU B 1 148 ? 40.437 -49.590 -46.679 1.00 74.61 ? 148 GLU B CG 1 ATOM 4144 C CD . GLU B 1 148 ? 41.517 -48.687 -47.234 1.00 93.96 ? 148 GLU B CD 1 ATOM 4145 O OE1 . GLU B 1 148 ? 41.559 -48.474 -48.471 1.00 120.55 ? 148 GLU B OE1 1 ATOM 4146 O OE2 . GLU B 1 148 ? 42.347 -48.218 -46.426 1.00 64.90 ? 148 GLU B OE2 1 ATOM 4147 N N . HIS B 1 149 ? 36.808 -49.712 -47.603 1.00 66.98 ? 149 HIS B N 1 ATOM 4148 C CA . HIS B 1 149 ? 35.790 -48.731 -47.201 1.00 66.14 ? 149 HIS B CA 1 ATOM 4149 C C . HIS B 1 149 ? 34.368 -49.233 -47.107 1.00 70.38 ? 149 HIS B C 1 ATOM 4150 O O . HIS B 1 149 ? 33.589 -48.624 -46.372 1.00 71.50 ? 149 HIS B O 1 ATOM 4151 C CB . HIS B 1 149 ? 35.833 -47.504 -48.100 1.00 66.58 ? 149 HIS B CB 1 ATOM 4152 C CG . HIS B 1 149 ? 37.060 -46.711 -47.851 1.00 70.24 ? 149 HIS B CG 1 ATOM 4153 N ND1 . HIS B 1 149 ? 38.119 -46.741 -48.731 1.00 72.28 ? 149 HIS B ND1 1 ATOM 4154 C CD2 . HIS B 1 149 ? 37.429 -46.019 -46.748 1.00 72.07 ? 149 HIS B CD2 1 ATOM 4155 C CE1 . HIS B 1 149 ? 39.073 -46.005 -48.175 1.00 71.42 ? 149 HIS B CE1 1 ATOM 4156 N NE2 . HIS B 1 149 ? 38.706 -45.550 -46.983 1.00 71.66 ? 149 HIS B NE2 1 ATOM 4157 N N . ALA B 1 150 ? 34.029 -50.327 -47.811 1.00 65.76 ? 150 ALA B N 1 ATOM 4158 C CA . ALA B 1 150 ? 32.686 -50.916 -47.936 1.00 65.49 ? 150 ALA B CA 1 ATOM 4159 C C . ALA B 1 150 ? 31.828 -50.998 -46.658 1.00 71.15 ? 150 ALA B C 1 ATOM 4160 O O . ALA B 1 150 ? 30.625 -50.768 -46.767 1.00 71.17 ? 150 ALA B O 1 ATOM 4161 C CB . ALA B 1 150 ? 32.772 -52.281 -48.578 1.00 66.13 ? 150 ALA B CB 1 ATOM 4162 N N . VAL B 1 151 ? 32.421 -51.303 -45.471 1.00 69.15 ? 151 VAL B N 1 ATOM 4163 C CA . VAL B 1 151 ? 31.735 -51.426 -44.162 1.00 68.75 ? 151 VAL B CA 1 ATOM 4164 C C . VAL B 1 151 ? 30.873 -50.189 -43.858 1.00 72.30 ? 151 VAL B C 1 ATOM 4165 O O . VAL B 1 151 ? 31.409 -49.082 -43.699 1.00 69.67 ? 151 VAL B O 1 ATOM 4166 C CB . VAL B 1 151 ? 32.721 -51.763 -42.996 1.00 72.23 ? 151 VAL B CB 1 ATOM 4167 C CG1 . VAL B 1 151 ? 32.033 -51.752 -41.633 1.00 71.67 ? 151 VAL B CG1 1 ATOM 4168 C CG2 . VAL B 1 151 ? 33.393 -53.098 -43.218 1.00 72.28 ? 151 VAL B CG2 1 ATOM 4169 N N . GLY B 1 152 ? 29.555 -50.410 -43.819 1.00 70.73 ? 152 GLY B N 1 ATOM 4170 C CA . GLY B 1 152 ? 28.539 -49.401 -43.555 1.00 71.92 ? 152 GLY B CA 1 ATOM 4171 C C . GLY B 1 152 ? 28.624 -48.155 -44.415 1.00 79.41 ? 152 GLY B C 1 ATOM 4172 O O . GLY B 1 152 ? 28.216 -47.079 -43.959 1.00 77.65 ? 152 GLY B O 1 ATOM 4173 N N . ASN B 1 153 ? 29.178 -48.277 -45.661 1.00 80.04 ? 153 ASN B N 1 ATOM 4174 C CA . ASN B 1 153 ? 29.336 -47.164 -46.604 1.00 81.00 ? 153 ASN B CA 1 ATOM 4175 C C . ASN B 1 153 ? 27.955 -46.851 -47.177 1.00 88.03 ? 153 ASN B C 1 ATOM 4176 O O . ASN B 1 153 ? 27.437 -47.583 -48.034 1.00 87.42 ? 153 ASN B O 1 ATOM 4177 C CB . ASN B 1 153 ? 30.369 -47.494 -47.698 1.00 81.47 ? 153 ASN B CB 1 ATOM 4178 C CG . ASN B 1 153 ? 31.001 -46.282 -48.367 1.00 103.40 ? 153 ASN B CG 1 ATOM 4179 O OD1 . ASN B 1 153 ? 30.612 -45.910 -49.487 1.00 108.92 ? 153 ASN B OD1 1 ATOM 4180 N ND2 . ASN B 1 153 ? 32.012 -45.686 -47.688 1.00 81.78 ? 153 ASN B ND2 1 ATOM 4181 N N . ASP B 1 154 ? 27.318 -45.815 -46.576 1.00 86.42 ? 154 ASP B N 1 ATOM 4182 C CA . ASP B 1 154 ? 25.980 -45.265 -46.866 1.00 86.37 ? 154 ASP B CA 1 ATOM 4183 C C . ASP B 1 154 ? 25.899 -44.661 -48.251 1.00 89.19 ? 154 ASP B C 1 ATOM 4184 O O . ASP B 1 154 ? 24.833 -44.699 -48.865 1.00 88.83 ? 154 ASP B O 1 ATOM 4185 C CB . ASP B 1 154 ? 25.587 -44.208 -45.805 1.00 88.63 ? 154 ASP B CB 1 ATOM 4186 C CG . ASP B 1 154 ? 26.699 -43.261 -45.320 1.00 107.42 ? 154 ASP B CG 1 ATOM 4187 O OD1 . ASP B 1 154 ? 27.756 -43.145 -46.021 1.00 109.16 ? 154 ASP B OD1 1 ATOM 4188 O OD2 . ASP B 1 154 ? 26.517 -42.634 -44.252 1.00 115.33 ? 154 ASP B OD2 1 ATOM 4189 N N . THR B 1 155 ? 27.036 -44.098 -48.719 1.00 85.63 ? 155 THR B N 1 ATOM 4190 C CA . THR B 1 155 ? 27.295 -43.430 -49.996 1.00 85.69 ? 155 THR B CA 1 ATOM 4191 C C . THR B 1 155 ? 26.665 -44.179 -51.203 1.00 93.54 ? 155 THR B C 1 ATOM 4192 O O . THR B 1 155 ? 25.865 -43.583 -51.932 1.00 95.20 ? 155 THR B O 1 ATOM 4193 C CB . THR B 1 155 ? 28.802 -43.173 -50.135 1.00 84.84 ? 155 THR B CB 1 ATOM 4194 O OG1 . THR B 1 155 ? 29.228 -42.352 -49.050 1.00 76.03 ? 155 THR B OG1 1 ATOM 4195 C CG2 . THR B 1 155 ? 29.151 -42.488 -51.417 1.00 86.08 ? 155 THR B CG2 1 ATOM 4196 N N . GLY B 1 156 ? 27.009 -45.444 -51.414 1.00 89.24 ? 156 GLY B N 1 ATOM 4197 C CA . GLY B 1 156 ? 26.398 -46.196 -52.512 1.00 87.77 ? 156 GLY B CA 1 ATOM 4198 C C . GLY B 1 156 ? 27.322 -46.571 -53.651 1.00 86.46 ? 156 GLY B C 1 ATOM 4199 O O . GLY B 1 156 ? 26.915 -47.301 -54.571 1.00 86.41 ? 156 GLY B O 1 ATOM 4200 N N . LYS B 1 157 ? 28.579 -46.093 -53.567 1.00 77.44 ? 157 LYS B N 1 ATOM 4201 C CA . LYS B 1 157 ? 29.634 -46.360 -54.537 1.00 75.18 ? 157 LYS B CA 1 ATOM 4202 C C . LYS B 1 157 ? 30.002 -47.878 -54.655 1.00 75.32 ? 157 LYS B C 1 ATOM 4203 O O . LYS B 1 157 ? 30.231 -48.377 -55.761 1.00 74.64 ? 157 LYS B O 1 ATOM 4204 C CB . LYS B 1 157 ? 30.853 -45.478 -54.228 1.00 76.67 ? 157 LYS B CB 1 ATOM 4205 C CG . LYS B 1 157 ? 30.586 -44.015 -54.560 1.00 90.18 ? 157 LYS B CG 1 ATOM 4206 C CD . LYS B 1 157 ? 31.626 -43.060 -53.972 1.00 96.41 ? 157 LYS B CD 1 ATOM 4207 C CE . LYS B 1 157 ? 31.347 -41.613 -54.336 1.00 89.63 ? 157 LYS B CE 1 ATOM 4208 N NZ . LYS B 1 157 ? 32.076 -40.661 -53.464 1.00 84.69 ? 157 LYS B NZ 1 ATOM 4209 N N . HIS B 1 158 ? 29.950 -48.619 -53.535 1.00 68.20 ? 158 HIS B N 1 ATOM 4210 C CA . HIS B 1 158 ? 30.338 -50.027 -53.515 1.00 65.70 ? 158 HIS B CA 1 ATOM 4211 C C . HIS B 1 158 ? 29.302 -51.010 -54.059 1.00 70.10 ? 158 HIS B C 1 ATOM 4212 O O . HIS B 1 158 ? 29.648 -52.178 -54.255 1.00 70.49 ? 158 HIS B O 1 ATOM 4213 C CB . HIS B 1 158 ? 30.783 -50.453 -52.109 1.00 64.55 ? 158 HIS B CB 1 ATOM 4214 C CG . HIS B 1 158 ? 31.951 -49.674 -51.580 1.00 66.47 ? 158 HIS B CG 1 ATOM 4215 N ND1 . HIS B 1 158 ? 31.800 -48.375 -51.108 1.00 67.22 ? 158 HIS B ND1 1 ATOM 4216 C CD2 . HIS B 1 158 ? 33.245 -50.049 -51.427 1.00 66.74 ? 158 HIS B CD2 1 ATOM 4217 C CE1 . HIS B 1 158 ? 32.999 -48.010 -50.680 1.00 65.92 ? 158 HIS B CE1 1 ATOM 4218 N NE2 . HIS B 1 158 ? 33.899 -48.987 -50.840 1.00 66.16 ? 158 HIS B NE2 1 ATOM 4219 N N . GLY B 1 159 ? 28.069 -50.572 -54.287 1.00 65.96 ? 159 GLY B N 1 ATOM 4220 C CA . GLY B 1 159 ? 27.032 -51.489 -54.741 1.00 65.66 ? 159 GLY B CA 1 ATOM 4221 C C . GLY B 1 159 ? 26.412 -51.140 -56.066 1.00 69.68 ? 159 GLY B C 1 ATOM 4222 O O . GLY B 1 159 ? 26.386 -49.967 -56.455 1.00 70.51 ? 159 GLY B O 1 ATOM 4223 N N . LYS B 1 160 ? 25.870 -52.170 -56.735 1.00 64.93 ? 160 LYS B N 1 ATOM 4224 C CA . LYS B 1 160 ? 25.166 -52.059 -58.012 1.00 64.27 ? 160 LYS B CA 1 ATOM 4225 C C . LYS B 1 160 ? 23.678 -51.746 -57.770 1.00 67.63 ? 160 LYS B C 1 ATOM 4226 O O . LYS B 1 160 ? 22.950 -52.563 -57.195 1.00 67.66 ? 160 LYS B O 1 ATOM 4227 C CB . LYS B 1 160 ? 25.334 -53.352 -58.850 1.00 65.86 ? 160 LYS B CB 1 ATOM 4228 C CG . LYS B 1 160 ? 24.654 -53.345 -60.218 1.00 71.65 ? 160 LYS B CG 1 ATOM 4229 C CD . LYS B 1 160 ? 25.559 -52.817 -61.330 1.00 87.81 ? 160 LYS B CD 1 ATOM 4230 C CE . LYS B 1 160 ? 24.795 -52.657 -62.624 1.00 104.98 ? 160 LYS B CE 1 ATOM 4231 N NZ . LYS B 1 160 ? 24.301 -51.264 -62.812 1.00 113.86 ? 160 LYS B NZ 1 ATOM 4232 N N . GLU B 1 161 ? 23.243 -50.560 -58.219 1.00 62.93 ? 161 GLU B N 1 ATOM 4233 C CA . GLU B 1 161 ? 21.858 -50.107 -58.149 1.00 62.20 ? 161 GLU B CA 1 ATOM 4234 C C . GLU B 1 161 ? 21.004 -50.914 -59.143 1.00 65.41 ? 161 GLU B C 1 ATOM 4235 O O . GLU B 1 161 ? 21.485 -51.263 -60.222 1.00 62.64 ? 161 GLU B O 1 ATOM 4236 C CB . GLU B 1 161 ? 21.779 -48.616 -58.489 1.00 63.49 ? 161 GLU B CB 1 ATOM 4237 C CG . GLU B 1 161 ? 21.796 -47.699 -57.277 1.00 75.39 ? 161 GLU B CG 1 ATOM 4238 C CD . GLU B 1 161 ? 21.151 -46.330 -57.443 1.00 96.42 ? 161 GLU B CD 1 ATOM 4239 O OE1 . GLU B 1 161 ? 20.161 -46.212 -58.202 1.00 85.45 ? 161 GLU B OE1 1 ATOM 4240 O OE2 . GLU B 1 161 ? 21.620 -45.377 -56.781 1.00 89.65 ? 161 GLU B OE2 1 ATOM 4241 N N . ILE B 1 162 ? 19.763 -51.246 -58.764 1.00 64.97 ? 162 ILE B N 1 ATOM 4242 C CA . ILE B 1 162 ? 18.851 -51.989 -59.642 1.00 66.54 ? 162 ILE B CA 1 ATOM 4243 C C . ILE B 1 162 ? 17.389 -51.530 -59.432 1.00 75.12 ? 162 ILE B C 1 ATOM 4244 O O . ILE B 1 162 ? 16.999 -51.213 -58.298 1.00 75.34 ? 162 ILE B O 1 ATOM 4245 C CB . ILE B 1 162 ? 19.042 -53.524 -59.566 1.00 69.39 ? 162 ILE B CB 1 ATOM 4246 C CG1 . ILE B 1 162 ? 18.689 -54.222 -60.882 1.00 69.79 ? 162 ILE B CG1 1 ATOM 4247 C CG2 . ILE B 1 162 ? 18.337 -54.150 -58.384 1.00 70.96 ? 162 ILE B CG2 1 ATOM 4248 C CD1 . ILE B 1 162 ? 19.516 -53.823 -62.207 1.00 81.13 ? 162 ILE B CD1 1 ATOM 4249 N N . LYS B 1 163 ? 16.603 -51.467 -60.537 1.00 72.80 ? 163 LYS B N 1 ATOM 4250 C CA . LYS B 1 163 ? 15.226 -50.978 -60.555 1.00 73.01 ? 163 LYS B CA 1 ATOM 4251 C C . LYS B 1 163 ? 14.215 -52.072 -60.809 1.00 83.23 ? 163 LYS B C 1 ATOM 4252 O O . LYS B 1 163 ? 14.379 -52.891 -61.722 1.00 83.37 ? 163 LYS B O 1 ATOM 4253 C CB . LYS B 1 163 ? 15.053 -49.852 -61.590 1.00 73.50 ? 163 LYS B CB 1 ATOM 4254 C CG . LYS B 1 163 ? 16.189 -48.823 -61.650 1.00 73.54 ? 163 LYS B CG 1 ATOM 4255 C CD . LYS B 1 163 ? 16.014 -47.665 -60.672 1.00 77.66 ? 163 LYS B CD 1 ATOM 4256 C CE . LYS B 1 163 ? 17.187 -46.715 -60.667 1.00 91.03 ? 163 LYS B CE 1 ATOM 4257 N NZ . LYS B 1 163 ? 16.948 -45.540 -59.776 1.00 104.51 ? 163 LYS B NZ 1 ATOM 4258 N N . ILE B 1 164 ? 13.130 -52.064 -60.035 1.00 84.61 ? 164 ILE B N 1 ATOM 4259 C CA . ILE B 1 164 ? 12.062 -53.056 -60.179 1.00 86.45 ? 164 ILE B CA 1 ATOM 4260 C C . ILE B 1 164 ? 10.683 -52.358 -60.290 1.00 94.34 ? 164 ILE B C 1 ATOM 4261 O O . ILE B 1 164 ? 10.381 -51.411 -59.552 1.00 94.20 ? 164 ILE B O 1 ATOM 4262 C CB . ILE B 1 164 ? 12.168 -54.159 -59.068 1.00 89.45 ? 164 ILE B CB 1 ATOM 4263 C CG1 . ILE B 1 164 ? 12.941 -55.397 -59.573 1.00 90.49 ? 164 ILE B CG1 1 ATOM 4264 C CG2 . ILE B 1 164 ? 10.837 -54.552 -58.422 1.00 89.80 ? 164 ILE B CG2 1 ATOM 4265 C CD1 . ILE B 1 164 ? 12.268 -56.277 -60.734 1.00 103.80 ? 164 ILE B CD1 1 ATOM 4266 N N . THR B 1 165 ? 9.883 -52.827 -61.251 1.00 93.00 ? 165 THR B N 1 ATOM 4267 C CA . THR B 1 165 ? 8.546 -52.331 -61.551 1.00 94.26 ? 165 THR B CA 1 ATOM 4268 C C . THR B 1 165 ? 7.571 -53.508 -61.620 1.00 101.44 ? 165 THR B C 1 ATOM 4269 O O . THR B 1 165 ? 7.913 -54.522 -62.236 1.00 100.69 ? 165 THR B O 1 ATOM 4270 C CB . THR B 1 165 ? 8.538 -51.506 -62.865 1.00 107.24 ? 165 THR B CB 1 ATOM 4271 O OG1 . THR B 1 165 ? 7.239 -51.562 -63.475 1.00 111.01 ? 165 THR B OG1 1 ATOM 4272 C CG2 . THR B 1 165 ? 9.590 -51.964 -63.881 1.00 104.31 ? 165 THR B CG2 1 ATOM 4273 N N . PRO B 1 166 ? 6.330 -53.382 -61.071 1.00 100.47 ? 166 PRO B N 1 ATOM 4274 C CA . PRO B 1 166 ? 5.368 -54.499 -61.157 1.00 100.99 ? 166 PRO B CA 1 ATOM 4275 C C . PRO B 1 166 ? 5.255 -55.119 -62.546 1.00 108.14 ? 166 PRO B C 1 ATOM 4276 O O . PRO B 1 166 ? 5.210 -56.344 -62.650 1.00 108.11 ? 166 PRO B O 1 ATOM 4277 C CB . PRO B 1 166 ? 4.058 -53.870 -60.686 1.00 102.20 ? 166 PRO B CB 1 ATOM 4278 C CG . PRO B 1 166 ? 4.480 -52.820 -59.745 1.00 106.21 ? 166 PRO B CG 1 ATOM 4279 C CD . PRO B 1 166 ? 5.755 -52.251 -60.313 1.00 101.80 ? 166 PRO B CD 1 ATOM 4280 N N . GLN B 1 167 ? 5.294 -54.287 -63.604 1.00 107.28 ? 167 GLN B N 1 ATOM 4281 C CA . GLN B 1 167 ? 5.231 -54.743 -64.996 1.00 108.63 ? 167 GLN B CA 1 ATOM 4282 C C . GLN B 1 167 ? 6.439 -55.637 -65.344 1.00 115.10 ? 167 GLN B C 1 ATOM 4283 O O . GLN B 1 167 ? 6.236 -56.747 -65.846 1.00 114.11 ? 167 GLN B O 1 ATOM 4284 C CB . GLN B 1 167 ? 5.071 -53.557 -65.973 1.00 110.10 ? 167 GLN B CB 1 ATOM 4285 C CG . GLN B 1 167 ? 3.754 -52.780 -65.796 1.00 122.76 ? 167 GLN B CG 1 ATOM 4286 C CD . GLN B 1 167 ? 3.639 -51.530 -66.646 1.00 141.11 ? 167 GLN B CD 1 ATOM 4287 O OE1 . GLN B 1 167 ? 2.610 -51.286 -67.288 1.00 135.85 ? 167 GLN B OE1 1 ATOM 4288 N NE2 . GLN B 1 167 ? 4.659 -50.678 -66.626 1.00 134.01 ? 167 GLN B NE2 1 ATOM 4289 N N . SER B 1 168 ? 7.678 -55.188 -65.011 1.00 114.34 ? 168 SER B N 1 ATOM 4290 C CA . SER B 1 168 ? 8.891 -55.985 -65.235 1.00 115.43 ? 168 SER B CA 1 ATOM 4291 C C . SER B 1 168 ? 9.166 -56.879 -64.004 1.00 123.14 ? 168 SER B C 1 ATOM 4292 O O . SER B 1 168 ? 9.708 -56.423 -62.987 1.00 123.05 ? 168 SER B O 1 ATOM 4293 C CB . SER B 1 168 ? 10.087 -55.121 -65.656 1.00 118.26 ? 168 SER B CB 1 ATOM 4294 O OG . SER B 1 168 ? 10.935 -54.676 -64.607 1.00 124.88 ? 168 SER B OG 1 ATOM 4295 N N . SER B 1 169 ? 8.705 -58.150 -64.094 1.00 121.62 ? 169 SER B N 1 ATOM 4296 C CA . SER B 1 169 ? 8.796 -59.184 -63.051 1.00 121.65 ? 169 SER B CA 1 ATOM 4297 C C . SER B 1 169 ? 10.254 -59.525 -62.643 1.00 124.46 ? 169 SER B C 1 ATOM 4298 O O . SER B 1 169 ? 10.591 -59.414 -61.455 1.00 124.18 ? 169 SER B O 1 ATOM 4299 C CB . SER B 1 169 ? 8.033 -60.444 -63.475 1.00 125.06 ? 169 SER B CB 1 ATOM 4300 O OG . SER B 1 169 ? 6.690 -60.176 -63.851 1.00 131.05 ? 169 SER B OG 1 ATOM 4301 N N . THR B 1 170 ? 11.114 -59.887 -63.638 1.00 118.94 ? 170 THR B N 1 ATOM 4302 C CA . THR B 1 170 ? 12.516 -60.279 -63.429 1.00 117.39 ? 170 THR B CA 1 ATOM 4303 C C . THR B 1 170 ? 13.577 -59.260 -63.893 1.00 118.54 ? 170 THR B C 1 ATOM 4304 O O . THR B 1 170 ? 13.417 -58.609 -64.931 1.00 118.04 ? 170 THR B O 1 ATOM 4305 C CB . THR B 1 170 ? 12.804 -61.664 -64.074 1.00 120.14 ? 170 THR B CB 1 ATOM 4306 O OG1 . THR B 1 170 ? 14.190 -61.997 -63.907 1.00 119.92 ? 170 THR B OG1 1 ATOM 4307 C CG2 . THR B 1 170 ? 12.413 -61.741 -65.556 1.00 114.78 ? 170 THR B CG2 1 ATOM 4308 N N . THR B 1 171 ? 14.685 -59.187 -63.117 1.00 112.65 ? 171 THR B N 1 ATOM 4309 C CA . THR B 1 171 ? 15.906 -58.438 -63.404 1.00 111.11 ? 171 THR B CA 1 ATOM 4310 C C . THR B 1 171 ? 17.078 -59.365 -63.104 1.00 111.64 ? 171 THR B C 1 ATOM 4311 O O . THR B 1 171 ? 17.263 -59.812 -61.971 1.00 111.07 ? 171 THR B O 1 ATOM 4312 C CB . THR B 1 171 ? 16.016 -57.060 -62.695 1.00 116.95 ? 171 THR B CB 1 ATOM 4313 O OG1 . THR B 1 171 ? 14.742 -56.429 -62.612 1.00 118.92 ? 171 THR B OG1 1 ATOM 4314 C CG2 . THR B 1 171 ? 16.982 -56.141 -63.397 1.00 112.49 ? 171 THR B CG2 1 ATOM 4315 N N . GLU B 1 172 ? 17.793 -59.734 -64.149 1.00 105.74 ? 172 GLU B N 1 ATOM 4316 C CA . GLU B 1 172 ? 18.990 -60.555 -64.076 1.00 104.08 ? 172 GLU B CA 1 ATOM 4317 C C . GLU B 1 172 ? 20.078 -59.469 -63.971 1.00 104.19 ? 172 GLU B C 1 ATOM 4318 O O . GLU B 1 172 ? 20.342 -58.798 -64.953 1.00 103.05 ? 172 GLU B O 1 ATOM 4319 C CB . GLU B 1 172 ? 19.121 -61.342 -65.393 1.00 105.42 ? 172 GLU B CB 1 ATOM 4320 C CG . GLU B 1 172 ? 19.490 -62.809 -65.283 1.00 117.31 ? 172 GLU B CG 1 ATOM 4321 C CD . GLU B 1 172 ? 19.922 -63.451 -66.595 1.00 142.91 ? 172 GLU B CD 1 ATOM 4322 O OE1 . GLU B 1 172 ? 19.447 -63.017 -67.671 1.00 135.08 ? 172 GLU B OE1 1 ATOM 4323 O OE2 . GLU B 1 172 ? 20.743 -64.395 -66.543 1.00 140.05 ? 172 GLU B OE2 1 ATOM 4324 N N . ALA B 1 173 ? 20.592 -59.185 -62.772 1.00 99.00 ? 173 ALA B N 1 ATOM 4325 C CA . ALA B 1 173 ? 21.575 -58.114 -62.638 1.00 97.64 ? 173 ALA B CA 1 ATOM 4326 C C . ALA B 1 173 ? 22.968 -58.641 -62.466 1.00 99.60 ? 173 ALA B C 1 ATOM 4327 O O . ALA B 1 173 ? 23.220 -59.507 -61.627 1.00 98.35 ? 173 ALA B O 1 ATOM 4328 C CB . ALA B 1 173 ? 21.208 -57.174 -61.505 1.00 98.26 ? 173 ALA B CB 1 ATOM 4329 N N . GLU B 1 174 ? 23.878 -58.087 -63.266 1.00 95.89 ? 174 GLU B N 1 ATOM 4330 C CA . GLU B 1 174 ? 25.296 -58.426 -63.313 1.00 95.23 ? 174 GLU B CA 1 ATOM 4331 C C . GLU B 1 174 ? 26.088 -57.696 -62.219 1.00 97.53 ? 174 GLU B C 1 ATOM 4332 O O . GLU B 1 174 ? 25.893 -56.497 -62.001 1.00 96.52 ? 174 GLU B O 1 ATOM 4333 C CB . GLU B 1 174 ? 25.843 -58.096 -64.717 1.00 96.49 ? 174 GLU B CB 1 ATOM 4334 C CG . GLU B 1 174 ? 27.206 -58.678 -65.045 1.00 107.69 ? 174 GLU B CG 1 ATOM 4335 C CD . GLU B 1 174 ? 27.246 -60.139 -65.447 1.00 133.36 ? 174 GLU B CD 1 ATOM 4336 O OE1 . GLU B 1 174 ? 26.276 -60.607 -66.088 1.00 127.23 ? 174 GLU B OE1 1 ATOM 4337 O OE2 . GLU B 1 174 ? 28.277 -60.799 -65.175 1.00 128.66 ? 174 GLU B OE2 1 ATOM 4338 N N . LEU B 1 175 ? 26.989 -58.443 -61.554 1.00 93.38 ? 175 LEU B N 1 ATOM 4339 C CA . LEU B 1 175 ? 27.915 -58.006 -60.509 1.00 92.82 ? 175 LEU B CA 1 ATOM 4340 C C . LEU B 1 175 ? 29.371 -58.245 -60.978 1.00 95.77 ? 175 LEU B C 1 ATOM 4341 O O . LEU B 1 175 ? 29.771 -59.383 -61.267 1.00 94.14 ? 175 LEU B O 1 ATOM 4342 C CB . LEU B 1 175 ? 27.620 -58.730 -59.173 1.00 92.48 ? 175 LEU B CB 1 ATOM 4343 C CG . LEU B 1 175 ? 26.258 -58.446 -58.534 1.00 95.89 ? 175 LEU B CG 1 ATOM 4344 C CD1 . LEU B 1 175 ? 25.869 -59.536 -57.588 1.00 95.46 ? 175 LEU B CD1 1 ATOM 4345 C CD2 . LEU B 1 175 ? 26.260 -57.121 -57.801 1.00 97.30 ? 175 LEU B CD2 1 ATOM 4346 N N . THR B 1 176 ? 30.127 -57.138 -61.101 1.00 92.03 ? 176 THR B N 1 ATOM 4347 C CA . THR B 1 176 ? 31.522 -57.081 -61.538 1.00 91.56 ? 176 THR B CA 1 ATOM 4348 C C . THR B 1 176 ? 32.456 -57.947 -60.645 1.00 93.33 ? 176 THR B C 1 ATOM 4349 O O . THR B 1 176 ? 32.945 -57.506 -59.593 1.00 91.73 ? 176 THR B O 1 ATOM 4350 C CB . THR B 1 176 ? 31.971 -55.606 -61.650 1.00 105.39 ? 176 THR B CB 1 ATOM 4351 O OG1 . THR B 1 176 ? 30.903 -54.816 -62.187 1.00 108.03 ? 176 THR B OG1 1 ATOM 4352 C CG2 . THR B 1 176 ? 33.233 -55.428 -62.492 1.00 105.06 ? 176 THR B CG2 1 ATOM 4353 N N . GLY B 1 177 ? 32.689 -59.176 -61.103 1.00 88.73 ? 177 GLY B N 1 ATOM 4354 C CA . GLY B 1 177 ? 33.577 -60.124 -60.440 1.00 87.50 ? 177 GLY B CA 1 ATOM 4355 C C . GLY B 1 177 ? 32.879 -61.317 -59.833 1.00 90.01 ? 177 GLY B C 1 ATOM 4356 O O . GLY B 1 177 ? 33.555 -62.254 -59.405 1.00 90.76 ? 177 GLY B O 1 ATOM 4357 N N . TYR B 1 178 ? 31.531 -61.309 -59.797 1.00 83.98 ? 178 TYR B N 1 ATOM 4358 C CA . TYR B 1 178 ? 30.760 -62.381 -59.161 1.00 82.49 ? 178 TYR B CA 1 ATOM 4359 C C . TYR B 1 178 ? 29.739 -63.054 -60.084 1.00 84.23 ? 178 TYR B C 1 ATOM 4360 O O . TYR B 1 178 ? 29.144 -64.060 -59.718 1.00 82.37 ? 178 TYR B O 1 ATOM 4361 C CB . TYR B 1 178 ? 30.087 -61.844 -57.872 1.00 82.89 ? 178 TYR B CB 1 ATOM 4362 C CG . TYR B 1 178 ? 31.075 -61.254 -56.877 1.00 83.13 ? 178 TYR B CG 1 ATOM 4363 C CD1 . TYR B 1 178 ? 31.722 -62.060 -55.948 1.00 84.99 ? 178 TYR B CD1 1 ATOM 4364 C CD2 . TYR B 1 178 ? 31.404 -59.900 -56.904 1.00 83.11 ? 178 TYR B CD2 1 ATOM 4365 C CE1 . TYR B 1 178 ? 32.646 -61.532 -55.044 1.00 85.36 ? 178 TYR B CE1 1 ATOM 4366 C CE2 . TYR B 1 178 ? 32.337 -59.359 -56.010 1.00 83.64 ? 178 TYR B CE2 1 ATOM 4367 C CZ . TYR B 1 178 ? 32.952 -60.178 -55.077 1.00 90.76 ? 178 TYR B CZ 1 ATOM 4368 O OH . TYR B 1 178 ? 33.871 -59.651 -54.192 1.00 92.07 ? 178 TYR B OH 1 ATOM 4369 N N . GLY B 1 179 ? 29.535 -62.484 -61.259 1.00 81.31 ? 179 GLY B N 1 ATOM 4370 C CA . GLY B 1 179 ? 28.559 -62.982 -62.222 1.00 81.29 ? 179 GLY B CA 1 ATOM 4371 C C . GLY B 1 179 ? 27.215 -62.279 -62.125 1.00 84.99 ? 179 GLY B C 1 ATOM 4372 O O . GLY B 1 179 ? 27.140 -61.130 -61.681 1.00 82.95 ? 179 GLY B O 1 ATOM 4373 N N . THR B 1 180 ? 26.140 -62.971 -62.527 1.00 83.16 ? 180 THR B N 1 ATOM 4374 C CA . THR B 1 180 ? 24.794 -62.405 -62.520 1.00 84.46 ? 180 THR B CA 1 ATOM 4375 C C . THR B 1 180 ? 23.926 -63.011 -61.408 1.00 93.96 ? 180 THR B C 1 ATOM 4376 O O . THR B 1 180 ? 24.129 -64.154 -60.996 1.00 94.37 ? 180 THR B O 1 ATOM 4377 C CB . THR B 1 180 ? 24.171 -62.504 -63.945 1.00 89.64 ? 180 THR B CB 1 ATOM 4378 O OG1 . THR B 1 180 ? 23.813 -61.214 -64.443 1.00 87.84 ? 180 THR B OG1 1 ATOM 4379 C CG2 . THR B 1 180 ? 23.002 -63.477 -64.058 1.00 86.05 ? 180 THR B CG2 1 ATOM 4380 N N . VAL B 1 181 ? 22.958 -62.225 -60.927 1.00 94.09 ? 181 VAL B N 1 ATOM 4381 C CA . VAL B 1 181 ? 21.988 -62.634 -59.914 1.00 94.60 ? 181 VAL B CA 1 ATOM 4382 C C . VAL B 1 181 ? 20.587 -62.385 -60.445 1.00 99.30 ? 181 VAL B C 1 ATOM 4383 O O . VAL B 1 181 ? 20.278 -61.261 -60.838 1.00 98.74 ? 181 VAL B O 1 ATOM 4384 C CB . VAL B 1 181 ? 22.254 -62.007 -58.510 1.00 98.25 ? 181 VAL B CB 1 ATOM 4385 C CG1 . VAL B 1 181 ? 22.230 -60.473 -58.532 1.00 97.82 ? 181 VAL B CG1 1 ATOM 4386 C CG2 . VAL B 1 181 ? 21.302 -62.566 -57.457 1.00 98.04 ? 181 VAL B CG2 1 ATOM 4387 N N . THR B 1 182 ? 19.769 -63.442 -60.498 1.00 96.57 ? 182 THR B N 1 ATOM 4388 C CA . THR B 1 182 ? 18.403 -63.342 -61.000 1.00 97.00 ? 182 THR B CA 1 ATOM 4389 C C . THR B 1 182 ? 17.495 -62.959 -59.832 1.00 101.13 ? 182 THR B C 1 ATOM 4390 O O . THR B 1 182 ? 17.457 -63.680 -58.840 1.00 100.33 ? 182 THR B O 1 ATOM 4391 C CB . THR B 1 182 ? 17.973 -64.645 -61.727 1.00 107.15 ? 182 THR B CB 1 ATOM 4392 O OG1 . THR B 1 182 ? 19.077 -65.222 -62.448 1.00 104.38 ? 182 THR B OG1 1 ATOM 4393 C CG2 . THR B 1 182 ? 16.780 -64.425 -62.661 1.00 105.63 ? 182 THR B CG2 1 ATOM 4394 N N . MET B 1 183 ? 16.803 -61.806 -59.930 1.00 98.79 ? 183 MET B N 1 ATOM 4395 C CA . MET B 1 183 ? 15.917 -61.307 -58.878 1.00 98.81 ? 183 MET B CA 1 ATOM 4396 C C . MET B 1 183 ? 14.491 -61.233 -59.400 1.00 101.81 ? 183 MET B C 1 ATOM 4397 O O . MET B 1 183 ? 14.255 -60.632 -60.446 1.00 101.37 ? 183 MET B O 1 ATOM 4398 C CB . MET B 1 183 ? 16.393 -59.927 -58.433 1.00 101.59 ? 183 MET B CB 1 ATOM 4399 C CG . MET B 1 183 ? 16.132 -59.611 -56.999 1.00 106.18 ? 183 MET B CG 1 ATOM 4400 S SD . MET B 1 183 ? 16.944 -58.013 -56.551 1.00 111.32 ? 183 MET B SD 1 ATOM 4401 C CE . MET B 1 183 ? 18.674 -58.446 -56.708 1.00 107.82 ? 183 MET B CE 1 ATOM 4402 N N . GLU B 1 184 ? 13.544 -61.854 -58.693 1.00 98.23 ? 184 GLU B N 1 ATOM 4403 C CA . GLU B 1 184 ? 12.131 -61.862 -59.085 1.00 98.00 ? 184 GLU B CA 1 ATOM 4404 C C . GLU B 1 184 ? 11.290 -61.266 -57.970 1.00 103.05 ? 184 GLU B C 1 ATOM 4405 O O . GLU B 1 184 ? 10.962 -61.961 -57.004 1.00 102.93 ? 184 GLU B O 1 ATOM 4406 C CB . GLU B 1 184 ? 11.682 -63.276 -59.502 1.00 99.21 ? 184 GLU B CB 1 ATOM 4407 C CG . GLU B 1 184 ? 11.839 -63.519 -60.995 1.00 110.42 ? 184 GLU B CG 1 ATOM 4408 C CD . GLU B 1 184 ? 12.342 -64.883 -61.437 1.00 132.32 ? 184 GLU B CD 1 ATOM 4409 O OE1 . GLU B 1 184 ? 11.567 -65.862 -61.354 1.00 122.79 ? 184 GLU B OE1 1 ATOM 4410 O OE2 . GLU B 1 184 ? 13.493 -64.964 -61.924 1.00 134.13 ? 184 GLU B OE2 1 ATOM 4411 N N . CYS B 1 185 ? 10.962 -59.961 -58.095 1.00 100.88 ? 185 CYS B N 1 ATOM 4412 C CA . CYS B 1 185 ? 10.249 -59.221 -57.055 1.00 101.59 ? 185 CYS B CA 1 ATOM 4413 C C . CYS B 1 185 ? 8.770 -59.014 -57.303 1.00 108.35 ? 185 CYS B C 1 ATOM 4414 O O . CYS B 1 185 ? 8.340 -58.761 -58.432 1.00 108.59 ? 185 CYS B O 1 ATOM 4415 C CB . CYS B 1 185 ? 10.946 -57.900 -56.774 1.00 101.75 ? 185 CYS B CB 1 ATOM 4416 S SG . CYS B 1 185 ? 12.640 -58.103 -56.176 1.00 105.72 ? 185 CYS B SG 1 ATOM 4417 N N . SER B 1 186 ? 8.007 -59.106 -56.194 1.00 106.39 ? 186 SER B N 1 ATOM 4418 C CA . SER B 1 186 ? 6.558 -58.946 -56.120 1.00 107.03 ? 186 SER B CA 1 ATOM 4419 C C . SER B 1 186 ? 6.169 -57.803 -55.172 1.00 113.01 ? 186 SER B C 1 ATOM 4420 O O . SER B 1 186 ? 6.574 -57.802 -54.003 1.00 112.56 ? 186 SER B O 1 ATOM 4421 C CB . SER B 1 186 ? 5.898 -60.240 -55.658 1.00 110.64 ? 186 SER B CB 1 ATOM 4422 O OG . SER B 1 186 ? 6.205 -61.308 -56.538 1.00 120.59 ? 186 SER B OG 1 ATOM 4423 N N . PRO B 1 187 ? 5.372 -56.826 -55.664 1.00 110.90 ? 187 PRO B N 1 ATOM 4424 C CA . PRO B 1 187 ? 4.947 -55.709 -54.793 1.00 110.87 ? 187 PRO B CA 1 ATOM 4425 C C . PRO B 1 187 ? 3.956 -56.111 -53.690 1.00 114.60 ? 187 PRO B C 1 ATOM 4426 O O . PRO B 1 187 ? 3.051 -56.905 -53.950 1.00 114.54 ? 187 PRO B O 1 ATOM 4427 C CB . PRO B 1 187 ? 4.290 -54.738 -55.779 1.00 112.81 ? 187 PRO B CB 1 ATOM 4428 C CG . PRO B 1 187 ? 3.821 -55.593 -56.923 1.00 117.30 ? 187 PRO B CG 1 ATOM 4429 C CD . PRO B 1 187 ? 4.833 -56.690 -57.037 1.00 112.67 ? 187 PRO B CD 1 ATOM 4430 N N . ARG B 1 188 ? 4.112 -55.573 -52.467 1.00 111.03 ? 188 ARG B N 1 ATOM 4431 C CA . ARG B 1 188 ? 3.173 -55.851 -51.376 1.00 111.45 ? 188 ARG B CA 1 ATOM 4432 C C . ARG B 1 188 ? 2.786 -54.551 -50.641 1.00 117.12 ? 188 ARG B C 1 ATOM 4433 O O . ARG B 1 188 ? 3.472 -54.090 -49.717 1.00 116.83 ? 188 ARG B O 1 ATOM 4434 C CB . ARG B 1 188 ? 3.657 -56.973 -50.434 1.00 112.71 ? 188 ARG B CB 1 ATOM 4435 C CG . ARG B 1 188 ? 2.678 -57.318 -49.290 1.00 128.23 ? 188 ARG B CG 1 ATOM 4436 C CD . ARG B 1 188 ? 1.762 -58.509 -49.556 1.00 144.04 ? 188 ARG B CD 1 ATOM 4437 N NE . ARG B 1 188 ? 1.626 -59.372 -48.370 1.00 154.72 ? 188 ARG B NE 1 ATOM 4438 C CZ . ARG B 1 188 ? 0.512 -59.534 -47.655 1.00 164.57 ? 188 ARG B CZ 1 ATOM 4439 N NH1 . ARG B 1 188 ? -0.606 -58.904 -47.999 1.00 148.28 ? 188 ARG B NH1 1 ATOM 4440 N NH2 . ARG B 1 188 ? 0.505 -60.334 -46.597 1.00 148.20 ? 188 ARG B NH2 1 ATOM 4441 N N . THR B 1 189 ? 1.678 -53.955 -51.114 1.00 114.39 ? 189 THR B N 1 ATOM 4442 C CA . THR B 1 189 ? 1.060 -52.718 -50.624 1.00 113.89 ? 189 THR B CA 1 ATOM 4443 C C . THR B 1 189 ? -0.064 -53.046 -49.614 1.00 118.14 ? 189 THR B C 1 ATOM 4444 O O . THR B 1 189 ? -0.420 -54.215 -49.450 1.00 118.07 ? 189 THR B O 1 ATOM 4445 C CB . THR B 1 189 ? 0.620 -51.841 -51.827 1.00 118.15 ? 189 THR B CB 1 ATOM 4446 O OG1 . THR B 1 189 ? -0.245 -50.795 -51.380 1.00 117.88 ? 189 THR B OG1 1 ATOM 4447 C CG2 . THR B 1 189 ? -0.067 -52.642 -52.941 1.00 115.09 ? 189 THR B CG2 1 ATOM 4448 N N . GLY B 1 190 ? -0.591 -52.020 -48.949 1.00 114.46 ? 190 GLY B N 1 ATOM 4449 C CA . GLY B 1 190 ? -1.653 -52.150 -47.956 1.00 113.97 ? 190 GLY B CA 1 ATOM 4450 C C . GLY B 1 190 ? -3.079 -52.134 -48.479 1.00 116.60 ? 190 GLY B C 1 ATOM 4451 O O . GLY B 1 190 ? -3.872 -52.993 -48.079 1.00 117.03 ? 190 GLY B O 1 ATOM 4452 N N . LEU B 1 191 ? -3.434 -51.140 -49.340 1.00 110.76 ? 191 LEU B N 1 ATOM 4453 C CA . LEU B 1 191 ? -4.781 -50.982 -49.928 1.00 109.86 ? 191 LEU B CA 1 ATOM 4454 C C . LEU B 1 191 ? -4.680 -50.953 -51.463 1.00 111.55 ? 191 LEU B C 1 ATOM 4455 O O . LEU B 1 191 ? -3.564 -50.838 -51.981 1.00 110.67 ? 191 LEU B O 1 ATOM 4456 C CB . LEU B 1 191 ? -5.418 -49.644 -49.433 1.00 110.01 ? 191 LEU B CB 1 ATOM 4457 C CG . LEU B 1 191 ? -6.938 -49.586 -49.057 1.00 114.06 ? 191 LEU B CG 1 ATOM 4458 C CD1 . LEU B 1 191 ? -7.254 -48.377 -48.210 1.00 113.82 ? 191 LEU B CD1 1 ATOM 4459 C CD2 . LEU B 1 191 ? -7.866 -49.567 -50.269 1.00 115.25 ? 191 LEU B CD2 1 ATOM 4460 N N . ASP B 1 192 ? -5.844 -51.043 -52.190 1.00 106.94 ? 192 ASP B N 1 ATOM 4461 C CA . ASP B 1 192 ? -5.902 -50.916 -53.656 1.00 106.04 ? 192 ASP B CA 1 ATOM 4462 C C . ASP B 1 192 ? -5.661 -49.452 -53.971 1.00 104.68 ? 192 ASP B C 1 ATOM 4463 O O . ASP B 1 192 ? -6.417 -48.578 -53.536 1.00 104.71 ? 192 ASP B O 1 ATOM 4464 C CB . ASP B 1 192 ? -7.238 -51.400 -54.278 1.00 108.84 ? 192 ASP B CB 1 ATOM 4465 C CG . ASP B 1 192 ? -7.402 -51.097 -55.784 1.00 125.54 ? 192 ASP B CG 1 ATOM 4466 O OD1 . ASP B 1 192 ? -6.468 -51.419 -56.571 1.00 126.01 ? 192 ASP B OD1 1 ATOM 4467 O OD2 . ASP B 1 192 ? -8.470 -50.550 -56.175 1.00 133.32 ? 192 ASP B OD2 1 ATOM 4468 N N . PHE B 1 193 ? -4.586 -49.202 -54.705 1.00 96.36 ? 193 PHE B N 1 ATOM 4469 C CA . PHE B 1 193 ? -4.107 -47.887 -55.064 1.00 93.99 ? 193 PHE B CA 1 ATOM 4470 C C . PHE B 1 193 ? -4.945 -47.079 -56.008 1.00 96.90 ? 193 PHE B C 1 ATOM 4471 O O . PHE B 1 193 ? -4.641 -45.898 -56.158 1.00 95.94 ? 193 PHE B O 1 ATOM 4472 C CB . PHE B 1 193 ? -2.732 -48.030 -55.660 1.00 95.07 ? 193 PHE B CB 1 ATOM 4473 C CG . PHE B 1 193 ? -1.634 -47.665 -54.719 1.00 95.90 ? 193 PHE B CG 1 ATOM 4474 C CD1 . PHE B 1 193 ? -1.366 -48.446 -53.604 1.00 98.48 ? 193 PHE B CD1 1 ATOM 4475 C CD2 . PHE B 1 193 ? -0.833 -46.562 -54.966 1.00 97.84 ? 193 PHE B CD2 1 ATOM 4476 C CE1 . PHE B 1 193 ? -0.338 -48.109 -52.735 1.00 99.31 ? 193 PHE B CE1 1 ATOM 4477 C CE2 . PHE B 1 193 ? 0.208 -46.236 -54.107 1.00 100.53 ? 193 PHE B CE2 1 ATOM 4478 C CZ . PHE B 1 193 ? 0.454 -47.015 -53.001 1.00 98.64 ? 193 PHE B CZ 1 ATOM 4479 N N . ASN B 1 194 ? -5.951 -47.671 -56.691 1.00 94.33 ? 194 ASN B N 1 ATOM 4480 C CA . ASN B 1 194 ? -6.717 -46.868 -57.653 1.00 94.44 ? 194 ASN B CA 1 ATOM 4481 C C . ASN B 1 194 ? -7.553 -45.777 -57.017 1.00 96.15 ? 194 ASN B C 1 ATOM 4482 O O . ASN B 1 194 ? -7.434 -44.610 -57.450 1.00 97.45 ? 194 ASN B O 1 ATOM 4483 C CB . ASN B 1 194 ? -7.581 -47.667 -58.633 1.00 97.80 ? 194 ASN B CB 1 ATOM 4484 C CG . ASN B 1 194 ? -8.267 -46.732 -59.627 1.00 121.64 ? 194 ASN B CG 1 ATOM 4485 O OD1 . ASN B 1 194 ? -7.636 -45.838 -60.225 1.00 115.53 ? 194 ASN B OD1 1 ATOM 4486 N ND2 . ASN B 1 194 ? -9.589 -46.813 -59.713 1.00 111.49 ? 194 ASN B ND2 1 ATOM 4487 N N . GLU B 1 195 ? -8.406 -46.142 -56.017 1.00 86.77 ? 195 GLU B N 1 ATOM 4488 C CA . GLU B 1 195 ? -9.262 -45.152 -55.380 1.00 83.42 ? 195 GLU B CA 1 ATOM 4489 C C . GLU B 1 195 ? -8.485 -44.170 -54.489 1.00 79.95 ? 195 GLU B C 1 ATOM 4490 O O . GLU B 1 195 ? -9.002 -43.119 -54.128 1.00 77.62 ? 195 GLU B O 1 ATOM 4491 C CB . GLU B 1 195 ? -10.410 -45.818 -54.643 1.00 84.75 ? 195 GLU B CB 1 ATOM 4492 C CG . GLU B 1 195 ? -11.658 -44.979 -54.722 1.00 94.64 ? 195 GLU B CG 1 ATOM 4493 C CD . GLU B 1 195 ? -12.473 -45.259 -55.957 1.00 125.28 ? 195 GLU B CD 1 ATOM 4494 O OE1 . GLU B 1 195 ? -13.323 -46.177 -55.898 1.00 122.40 ? 195 GLU B OE1 1 ATOM 4495 O OE2 . GLU B 1 195 ? -12.247 -44.584 -56.989 1.00 124.72 ? 195 GLU B OE2 1 ATOM 4496 N N . MET B 1 196 ? -7.221 -44.481 -54.208 1.00 73.76 ? 196 MET B N 1 ATOM 4497 C CA . MET B 1 196 ? -6.385 -43.633 -53.381 1.00 72.84 ? 196 MET B CA 1 ATOM 4498 C C . MET B 1 196 ? -5.703 -42.496 -54.159 1.00 73.64 ? 196 MET B C 1 ATOM 4499 O O . MET B 1 196 ? -5.403 -42.606 -55.361 1.00 73.18 ? 196 MET B O 1 ATOM 4500 C CB . MET B 1 196 ? -5.372 -44.452 -52.554 1.00 75.35 ? 196 MET B CB 1 ATOM 4501 C CG . MET B 1 196 ? -6.012 -45.368 -51.481 1.00 79.46 ? 196 MET B CG 1 ATOM 4502 S SD . MET B 1 196 ? -7.611 -44.832 -50.760 1.00 84.26 ? 196 MET B SD 1 ATOM 4503 C CE . MET B 1 196 ? -8.715 -46.093 -51.379 1.00 81.13 ? 196 MET B CE 1 ATOM 4504 N N . VAL B 1 197 ? -5.502 -41.380 -53.432 1.00 66.99 ? 197 VAL B N 1 ATOM 4505 C CA . VAL B 1 197 ? -4.898 -40.134 -53.876 1.00 65.45 ? 197 VAL B CA 1 ATOM 4506 C C . VAL B 1 197 ? -3.708 -39.841 -52.953 1.00 67.19 ? 197 VAL B C 1 ATOM 4507 O O . VAL B 1 197 ? -3.850 -39.903 -51.729 1.00 66.21 ? 197 VAL B O 1 ATOM 4508 C CB . VAL B 1 197 ? -5.924 -38.957 -53.867 1.00 68.67 ? 197 VAL B CB 1 ATOM 4509 C CG1 . VAL B 1 197 ? -5.322 -37.689 -54.462 1.00 68.57 ? 197 VAL B CG1 1 ATOM 4510 C CG2 . VAL B 1 197 ? -7.198 -39.311 -54.611 1.00 68.26 ? 197 VAL B CG2 1 ATOM 4511 N N . LEU B 1 198 ? -2.554 -39.502 -53.545 1.00 62.28 ? 198 LEU B N 1 ATOM 4512 C CA . LEU B 1 198 ? -1.359 -39.143 -52.799 1.00 61.73 ? 198 LEU B CA 1 ATOM 4513 C C . LEU B 1 198 ? -1.390 -37.644 -52.359 1.00 65.60 ? 198 LEU B C 1 ATOM 4514 O O . LEU B 1 198 ? -0.820 -36.754 -53.014 1.00 65.27 ? 198 LEU B O 1 ATOM 4515 C CB . LEU B 1 198 ? -0.075 -39.541 -53.566 1.00 61.47 ? 198 LEU B CB 1 ATOM 4516 C CG . LEU B 1 198 ? 1.324 -39.184 -52.973 1.00 65.47 ? 198 LEU B CG 1 ATOM 4517 C CD1 . LEU B 1 198 ? 1.548 -39.754 -51.542 1.00 64.72 ? 198 LEU B CD1 1 ATOM 4518 C CD2 . LEU B 1 198 ? 2.432 -39.655 -53.910 1.00 68.27 ? 198 LEU B CD2 1 ATOM 4519 N N . LEU B 1 199 ? -2.062 -37.392 -51.218 1.00 60.66 ? 199 LEU B N 1 ATOM 4520 C CA . LEU B 1 199 ? -2.182 -36.057 -50.641 1.00 59.08 ? 199 LEU B CA 1 ATOM 4521 C C . LEU B 1 199 ? -0.853 -35.559 -50.096 1.00 63.88 ? 199 LEU B C 1 ATOM 4522 O O . LEU B 1 199 ? -0.483 -35.881 -48.980 1.00 65.22 ? 199 LEU B O 1 ATOM 4523 C CB . LEU B 1 199 ? -3.297 -36.001 -49.557 1.00 57.67 ? 199 LEU B CB 1 ATOM 4524 C CG . LEU B 1 199 ? -3.666 -34.622 -48.991 1.00 58.88 ? 199 LEU B CG 1 ATOM 4525 C CD1 . LEU B 1 199 ? -3.705 -33.545 -50.071 1.00 58.11 ? 199 LEU B CD1 1 ATOM 4526 C CD2 . LEU B 1 199 ? -4.964 -34.678 -48.258 1.00 56.36 ? 199 LEU B CD2 1 ATOM 4527 N N . GLN B 1 200 ? -0.139 -34.791 -50.879 1.00 59.45 ? 200 GLN B N 1 ATOM 4528 C CA . GLN B 1 200 ? 1.096 -34.202 -50.401 1.00 59.27 ? 200 GLN B CA 1 ATOM 4529 C C . GLN B 1 200 ? 0.738 -32.850 -49.847 1.00 63.81 ? 200 GLN B C 1 ATOM 4530 O O . GLN B 1 200 ? 0.149 -32.024 -50.550 1.00 62.53 ? 200 GLN B O 1 ATOM 4531 C CB . GLN B 1 200 ? 2.094 -33.997 -51.544 1.00 60.96 ? 200 GLN B CB 1 ATOM 4532 C CG . GLN B 1 200 ? 2.792 -35.250 -52.018 1.00 90.56 ? 200 GLN B CG 1 ATOM 4533 C CD . GLN B 1 200 ? 3.600 -34.968 -53.262 1.00 121.80 ? 200 GLN B CD 1 ATOM 4534 O OE1 . GLN B 1 200 ? 3.062 -34.675 -54.339 1.00 117.25 ? 200 GLN B OE1 1 ATOM 4535 N NE2 . GLN B 1 200 ? 4.911 -35.057 -53.135 1.00 121.29 ? 200 GLN B NE2 1 ATOM 4536 N N . MET B 1 201 ? 1.104 -32.596 -48.598 1.00 62.90 ? 201 MET B N 1 ATOM 4537 C CA . MET B 1 201 ? 0.879 -31.274 -48.038 1.00 63.83 ? 201 MET B CA 1 ATOM 4538 C C . MET B 1 201 ? 2.131 -30.406 -48.255 1.00 74.51 ? 201 MET B C 1 ATOM 4539 O O . MET B 1 201 ? 2.273 -29.793 -49.326 1.00 76.36 ? 201 MET B O 1 ATOM 4540 C CB . MET B 1 201 ? 0.358 -31.309 -46.596 1.00 65.21 ? 201 MET B CB 1 ATOM 4541 C CG . MET B 1 201 ? -1.158 -31.220 -46.559 1.00 67.77 ? 201 MET B CG 1 ATOM 4542 S SD . MET B 1 201 ? -1.946 -30.659 -45.035 1.00 70.75 ? 201 MET B SD 1 ATOM 4543 C CE . MET B 1 201 ? -1.285 -28.994 -44.914 1.00 67.36 ? 201 MET B CE 1 ATOM 4544 N N . GLU B 1 202 ? 3.057 -30.404 -47.299 1.00 73.25 ? 202 GLU B N 1 ATOM 4545 C CA . GLU B 1 202 ? 4.299 -29.640 -47.400 1.00 73.90 ? 202 GLU B CA 1 ATOM 4546 C C . GLU B 1 202 ? 5.392 -30.678 -47.644 1.00 78.55 ? 202 GLU B C 1 ATOM 4547 O O . GLU B 1 202 ? 5.601 -31.117 -48.775 1.00 76.78 ? 202 GLU B O 1 ATOM 4548 C CB . GLU B 1 202 ? 4.530 -28.866 -46.082 1.00 75.33 ? 202 GLU B CB 1 ATOM 4549 C CG . GLU B 1 202 ? 4.168 -27.393 -46.149 1.00 87.54 ? 202 GLU B CG 1 ATOM 4550 C CD . GLU B 1 202 ? 5.220 -26.455 -46.718 1.00 113.66 ? 202 GLU B CD 1 ATOM 4551 O OE1 . GLU B 1 202 ? 6.431 -26.765 -46.612 1.00 120.75 ? 202 GLU B OE1 1 ATOM 4552 O OE2 . GLU B 1 202 ? 4.829 -25.373 -47.213 1.00 96.87 ? 202 GLU B OE2 1 ATOM 4553 N N . ASP B 1 203 ? 6.007 -31.124 -46.545 1.00 77.43 ? 203 ASP B N 1 ATOM 4554 C CA . ASP B 1 203 ? 7.019 -32.162 -46.434 1.00 78.32 ? 203 ASP B CA 1 ATOM 4555 C C . ASP B 1 203 ? 6.328 -33.422 -45.895 1.00 79.87 ? 203 ASP B C 1 ATOM 4556 O O . ASP B 1 203 ? 6.915 -34.509 -45.923 1.00 80.72 ? 203 ASP B O 1 ATOM 4557 C CB . ASP B 1 203 ? 8.146 -31.708 -45.476 1.00 81.98 ? 203 ASP B CB 1 ATOM 4558 C CG . ASP B 1 203 ? 7.703 -30.905 -44.254 1.00 103.66 ? 203 ASP B CG 1 ATOM 4559 O OD1 . ASP B 1 203 ? 6.539 -31.108 -43.783 1.00 106.18 ? 203 ASP B OD1 1 ATOM 4560 O OD2 . ASP B 1 203 ? 8.512 -30.076 -43.764 1.00 110.87 ? 203 ASP B OD2 1 ATOM 4561 N N . LYS B 1 204 ? 5.097 -33.265 -45.374 1.00 72.68 ? 204 LYS B N 1 ATOM 4562 C CA . LYS B 1 204 ? 4.275 -34.377 -44.893 1.00 71.14 ? 204 LYS B CA 1 ATOM 4563 C C . LYS B 1 204 ? 3.439 -34.900 -46.101 1.00 68.06 ? 204 LYS B C 1 ATOM 4564 O O . LYS B 1 204 ? 3.269 -34.156 -47.060 1.00 68.71 ? 204 LYS B O 1 ATOM 4565 C CB . LYS B 1 204 ? 3.385 -33.929 -43.705 1.00 75.29 ? 204 LYS B CB 1 ATOM 4566 C CG . LYS B 1 204 ? 4.141 -33.461 -42.427 1.00 91.91 ? 204 LYS B CG 1 ATOM 4567 C CD . LYS B 1 204 ? 3.209 -33.119 -41.211 1.00 98.04 ? 204 LYS B CD 1 ATOM 4568 C CE . LYS B 1 204 ? 2.825 -34.312 -40.333 1.00 105.76 ? 204 LYS B CE 1 ATOM 4569 N NZ . LYS B 1 204 ? 1.822 -33.974 -39.267 1.00 103.79 ? 204 LYS B NZ 1 ATOM 4570 N N . ALA B 1 205 ? 2.996 -36.170 -46.096 1.00 59.34 ? 205 ALA B N 1 ATOM 4571 C CA . ALA B 1 205 ? 2.255 -36.794 -47.212 1.00 57.86 ? 205 ALA B CA 1 ATOM 4572 C C . ALA B 1 205 ? 1.444 -37.981 -46.752 1.00 59.61 ? 205 ALA B C 1 ATOM 4573 O O . ALA B 1 205 ? 1.826 -38.617 -45.790 1.00 61.71 ? 205 ALA B O 1 ATOM 4574 C CB . ALA B 1 205 ? 3.204 -37.235 -48.306 1.00 58.78 ? 205 ALA B CB 1 ATOM 4575 N N . TRP B 1 206 ? 0.330 -38.279 -47.413 1.00 53.23 ? 206 TRP B N 1 ATOM 4576 C CA . TRP B 1 206 ? -0.612 -39.328 -47.011 1.00 52.30 ? 206 TRP B CA 1 ATOM 4577 C C . TRP B 1 206 ? -1.315 -39.910 -48.234 1.00 57.93 ? 206 TRP B C 1 ATOM 4578 O O . TRP B 1 206 ? -1.394 -39.253 -49.267 1.00 57.03 ? 206 TRP B O 1 ATOM 4579 C CB . TRP B 1 206 ? -1.735 -38.709 -46.157 1.00 50.25 ? 206 TRP B CB 1 ATOM 4580 C CG . TRP B 1 206 ? -1.373 -38.125 -44.834 1.00 50.50 ? 206 TRP B CG 1 ATOM 4581 C CD1 . TRP B 1 206 ? -1.630 -38.677 -43.626 1.00 53.34 ? 206 TRP B CD1 1 ATOM 4582 C CD2 . TRP B 1 206 ? -0.929 -36.786 -44.572 1.00 50.61 ? 206 TRP B CD2 1 ATOM 4583 N NE1 . TRP B 1 206 ? -1.256 -37.819 -42.622 1.00 52.90 ? 206 TRP B NE1 1 ATOM 4584 C CE2 . TRP B 1 206 ? -0.816 -36.650 -43.174 1.00 54.09 ? 206 TRP B CE2 1 ATOM 4585 C CE3 . TRP B 1 206 ? -0.584 -35.687 -45.382 1.00 52.47 ? 206 TRP B CE3 1 ATOM 4586 C CZ2 . TRP B 1 206 ? -0.355 -35.473 -42.563 1.00 53.31 ? 206 TRP B CZ2 1 ATOM 4587 C CZ3 . TRP B 1 206 ? -0.106 -34.524 -44.775 1.00 53.74 ? 206 TRP B CZ3 1 ATOM 4588 C CH2 . TRP B 1 206 ? -0.017 -34.421 -43.381 1.00 54.01 ? 206 TRP B CH2 1 ATOM 4589 N N . LEU B 1 207 ? -1.932 -41.075 -48.076 1.00 56.63 ? 207 LEU B N 1 ATOM 4590 C CA . LEU B 1 207 ? -2.680 -41.727 -49.131 1.00 58.93 ? 207 LEU B CA 1 ATOM 4591 C C . LEU B 1 207 ? -4.078 -41.802 -48.662 1.00 64.37 ? 207 LEU B C 1 ATOM 4592 O O . LEU B 1 207 ? -4.319 -42.276 -47.555 1.00 65.00 ? 207 LEU B O 1 ATOM 4593 C CB . LEU B 1 207 ? -2.134 -43.118 -49.451 1.00 60.49 ? 207 LEU B CB 1 ATOM 4594 C CG . LEU B 1 207 ? -2.036 -43.404 -50.969 1.00 67.95 ? 207 LEU B CG 1 ATOM 4595 C CD1 . LEU B 1 207 ? -0.757 -42.826 -51.580 1.00 68.03 ? 207 LEU B CD1 1 ATOM 4596 C CD2 . LEU B 1 207 ? -2.127 -44.882 -51.262 1.00 73.68 ? 207 LEU B CD2 1 ATOM 4597 N N . VAL B 1 208 ? -5.007 -41.262 -49.451 1.00 61.87 ? 208 VAL B N 1 ATOM 4598 C CA . VAL B 1 208 ? -6.390 -41.138 -49.016 1.00 62.28 ? 208 VAL B CA 1 ATOM 4599 C C . VAL B 1 208 ? -7.395 -41.294 -50.144 1.00 65.78 ? 208 VAL B C 1 ATOM 4600 O O . VAL B 1 208 ? -7.081 -40.987 -51.290 1.00 66.46 ? 208 VAL B O 1 ATOM 4601 C CB . VAL B 1 208 ? -6.587 -39.802 -48.234 1.00 67.36 ? 208 VAL B CB 1 ATOM 4602 C CG1 . VAL B 1 208 ? -6.524 -38.577 -49.145 1.00 67.12 ? 208 VAL B CG1 1 ATOM 4603 C CG2 . VAL B 1 208 ? -7.886 -39.820 -47.456 1.00 68.01 ? 208 VAL B CG2 1 ATOM 4604 N N . HIS B 1 209 ? -8.622 -41.718 -49.785 1.00 60.96 ? 209 HIS B N 1 ATOM 4605 C CA . HIS B 1 209 ? -9.752 -41.950 -50.656 1.00 60.60 ? 209 HIS B CA 1 ATOM 4606 C C . HIS B 1 209 ? -10.120 -40.773 -51.545 1.00 61.64 ? 209 HIS B C 1 ATOM 4607 O O . HIS B 1 209 ? -10.194 -39.626 -51.083 1.00 61.51 ? 209 HIS B O 1 ATOM 4608 C CB . HIS B 1 209 ? -10.944 -42.385 -49.827 1.00 62.79 ? 209 HIS B CB 1 ATOM 4609 C CG . HIS B 1 209 ? -11.953 -43.130 -50.639 1.00 67.83 ? 209 HIS B CG 1 ATOM 4610 N ND1 . HIS B 1 209 ? -11.659 -44.371 -51.203 1.00 69.94 ? 209 HIS B ND1 1 ATOM 4611 C CD2 . HIS B 1 209 ? -13.217 -42.775 -50.984 1.00 70.34 ? 209 HIS B CD2 1 ATOM 4612 C CE1 . HIS B 1 209 ? -12.758 -44.729 -51.853 1.00 69.68 ? 209 HIS B CE1 1 ATOM 4613 N NE2 . HIS B 1 209 ? -13.720 -43.798 -51.760 1.00 69.98 ? 209 HIS B NE2 1 ATOM 4614 N N . ARG B 1 210 ? -10.330 -41.077 -52.838 1.00 56.09 ? 210 ARG B N 1 ATOM 4615 C CA . ARG B 1 210 ? -10.693 -40.136 -53.894 1.00 55.18 ? 210 ARG B CA 1 ATOM 4616 C C . ARG B 1 210 ? -11.870 -39.264 -53.488 1.00 59.56 ? 210 ARG B C 1 ATOM 4617 O O . ARG B 1 210 ? -11.752 -38.039 -53.533 1.00 61.02 ? 210 ARG B O 1 ATOM 4618 C CB . ARG B 1 210 ? -11.003 -40.865 -55.209 1.00 53.84 ? 210 ARG B CB 1 ATOM 4619 C CG . ARG B 1 210 ? -11.443 -39.910 -56.303 1.00 67.23 ? 210 ARG B CG 1 ATOM 4620 C CD . ARG B 1 210 ? -12.162 -40.555 -57.475 1.00 75.79 ? 210 ARG B CD 1 ATOM 4621 N NE . ARG B 1 210 ? -12.102 -39.689 -58.658 1.00 76.38 ? 210 ARG B NE 1 ATOM 4622 C CZ . ARG B 1 210 ? -11.084 -39.669 -59.518 1.00 91.28 ? 210 ARG B CZ 1 ATOM 4623 N NH1 . ARG B 1 210 ? -10.044 -40.482 -59.348 1.00 84.07 ? 210 ARG B NH1 1 ATOM 4624 N NH2 . ARG B 1 210 ? -11.103 -38.845 -60.560 1.00 69.71 ? 210 ARG B NH2 1 ATOM 4625 N N . GLN B 1 211 ? -12.992 -39.898 -53.085 1.00 53.32 ? 211 GLN B N 1 ATOM 4626 C CA . GLN B 1 211 ? -14.223 -39.221 -52.689 1.00 51.55 ? 211 GLN B CA 1 ATOM 4627 C C . GLN B 1 211 ? -13.993 -38.237 -51.556 1.00 52.81 ? 211 GLN B C 1 ATOM 4628 O O . GLN B 1 211 ? -14.430 -37.099 -51.673 1.00 52.22 ? 211 GLN B O 1 ATOM 4629 C CB . GLN B 1 211 ? -15.351 -40.230 -52.350 1.00 52.37 ? 211 GLN B CB 1 ATOM 4630 C CG . GLN B 1 211 ? -16.772 -39.656 -52.437 1.00 67.41 ? 211 GLN B CG 1 ATOM 4631 C CD . GLN B 1 211 ? -17.110 -39.030 -53.796 1.00 102.89 ? 211 GLN B CD 1 ATOM 4632 O OE1 . GLN B 1 211 ? -17.466 -37.841 -53.896 1.00 94.81 ? 211 GLN B OE1 1 ATOM 4633 N NE2 . GLN B 1 211 ? -17.013 -39.817 -54.878 1.00 102.33 ? 211 GLN B NE2 1 ATOM 4634 N N . TRP B 1 212 ? -13.294 -38.661 -50.477 1.00 47.34 ? 212 TRP B N 1 ATOM 4635 C CA . TRP B 1 212 ? -13.014 -37.804 -49.322 1.00 45.67 ? 212 TRP B CA 1 ATOM 4636 C C . TRP B 1 212 ? -12.260 -36.565 -49.817 1.00 49.34 ? 212 TRP B C 1 ATOM 4637 O O . TRP B 1 212 ? -12.680 -35.423 -49.543 1.00 48.69 ? 212 TRP B O 1 ATOM 4638 C CB . TRP B 1 212 ? -12.206 -38.564 -48.257 1.00 43.90 ? 212 TRP B CB 1 ATOM 4639 C CG . TRP B 1 212 ? -11.900 -37.767 -47.026 1.00 44.91 ? 212 TRP B CG 1 ATOM 4640 C CD1 . TRP B 1 212 ? -12.700 -37.609 -45.934 1.00 47.77 ? 212 TRP B CD1 1 ATOM 4641 C CD2 . TRP B 1 212 ? -10.692 -37.019 -46.755 1.00 44.94 ? 212 TRP B CD2 1 ATOM 4642 N NE1 . TRP B 1 212 ? -12.084 -36.782 -45.009 1.00 47.50 ? 212 TRP B NE1 1 ATOM 4643 C CE2 . TRP B 1 212 ? -10.857 -36.397 -45.495 1.00 48.45 ? 212 TRP B CE2 1 ATOM 4644 C CE3 . TRP B 1 212 ? -9.532 -36.724 -47.506 1.00 45.66 ? 212 TRP B CE3 1 ATOM 4645 C CZ2 . TRP B 1 212 ? -9.896 -35.536 -44.953 1.00 46.71 ? 212 TRP B CZ2 1 ATOM 4646 C CZ3 . TRP B 1 212 ? -8.578 -35.883 -46.954 1.00 46.31 ? 212 TRP B CZ3 1 ATOM 4647 C CH2 . TRP B 1 212 ? -8.770 -35.294 -45.700 1.00 46.60 ? 212 TRP B CH2 1 ATOM 4648 N N . PHE B 1 213 ? -11.182 -36.803 -50.611 1.00 44.13 ? 213 PHE B N 1 ATOM 4649 C CA . PHE B 1 213 ? -10.377 -35.746 -51.189 1.00 42.02 ? 213 PHE B CA 1 ATOM 4650 C C . PHE B 1 213 ? -11.241 -34.742 -51.944 1.00 44.37 ? 213 PHE B C 1 ATOM 4651 O O . PHE B 1 213 ? -11.271 -33.595 -51.550 1.00 45.32 ? 213 PHE B O 1 ATOM 4652 C CB . PHE B 1 213 ? -9.298 -36.327 -52.098 1.00 42.86 ? 213 PHE B CB 1 ATOM 4653 C CG . PHE B 1 213 ? -8.464 -35.306 -52.857 1.00 43.01 ? 213 PHE B CG 1 ATOM 4654 C CD1 . PHE B 1 213 ? -7.436 -34.617 -52.229 1.00 44.43 ? 213 PHE B CD1 1 ATOM 4655 C CD2 . PHE B 1 213 ? -8.668 -35.085 -54.214 1.00 43.84 ? 213 PHE B CD2 1 ATOM 4656 C CE1 . PHE B 1 213 ? -6.643 -33.705 -52.945 1.00 44.82 ? 213 PHE B CE1 1 ATOM 4657 C CE2 . PHE B 1 213 ? -7.878 -34.171 -54.918 1.00 45.22 ? 213 PHE B CE2 1 ATOM 4658 C CZ . PHE B 1 213 ? -6.876 -33.482 -54.278 1.00 42.86 ? 213 PHE B CZ 1 ATOM 4659 N N . LEU B 1 214 ? -11.990 -35.157 -52.964 1.00 39.07 ? 214 LEU B N 1 ATOM 4660 C CA . LEU B 1 214 ? -12.801 -34.220 -53.763 1.00 38.16 ? 214 LEU B CA 1 ATOM 4661 C C . LEU B 1 214 ? -13.779 -33.409 -52.933 1.00 46.58 ? 214 LEU B C 1 ATOM 4662 O O . LEU B 1 214 ? -13.893 -32.195 -53.149 1.00 48.53 ? 214 LEU B O 1 ATOM 4663 C CB . LEU B 1 214 ? -13.528 -34.892 -54.956 1.00 37.03 ? 214 LEU B CB 1 ATOM 4664 C CG . LEU B 1 214 ? -12.721 -35.882 -55.864 1.00 38.98 ? 214 LEU B CG 1 ATOM 4665 C CD1 . LEU B 1 214 ? -13.655 -36.834 -56.593 1.00 39.29 ? 214 LEU B CD1 1 ATOM 4666 C CD2 . LEU B 1 214 ? -11.709 -35.184 -56.791 1.00 31.72 ? 214 LEU B CD2 1 ATOM 4667 N N . ASP B 1 215 ? -14.426 -34.056 -51.931 1.00 44.05 ? 215 ASP B N 1 ATOM 4668 C CA . ASP B 1 215 ? -15.435 -33.474 -51.016 1.00 42.99 ? 215 ASP B CA 1 ATOM 4669 C C . ASP B 1 215 ? -14.856 -32.490 -49.944 1.00 45.03 ? 215 ASP B C 1 ATOM 4670 O O . ASP B 1 215 ? -15.584 -32.073 -49.036 1.00 45.51 ? 215 ASP B O 1 ATOM 4671 C CB . ASP B 1 215 ? -16.254 -34.601 -50.352 1.00 44.49 ? 215 ASP B CB 1 ATOM 4672 C CG . ASP B 1 215 ? -17.072 -35.446 -51.303 1.00 67.08 ? 215 ASP B CG 1 ATOM 4673 O OD1 . ASP B 1 215 ? -16.717 -35.507 -52.500 1.00 71.29 ? 215 ASP B OD1 1 ATOM 4674 O OD2 . ASP B 1 215 ? -18.064 -36.062 -50.850 1.00 78.71 ? 215 ASP B OD2 1 ATOM 4675 N N . LEU B 1 216 ? -13.572 -32.110 -50.051 1.00 38.35 ? 216 LEU B N 1 ATOM 4676 C CA . LEU B 1 216 ? -13.004 -31.200 -49.085 1.00 37.16 ? 216 LEU B CA 1 ATOM 4677 C C . LEU B 1 216 ? -13.559 -29.829 -49.329 1.00 44.69 ? 216 LEU B C 1 ATOM 4678 O O . LEU B 1 216 ? -13.529 -29.339 -50.472 1.00 45.07 ? 216 LEU B O 1 ATOM 4679 C CB . LEU B 1 216 ? -11.474 -31.172 -49.080 1.00 36.51 ? 216 LEU B CB 1 ATOM 4680 C CG . LEU B 1 216 ? -10.711 -32.430 -48.651 1.00 40.26 ? 216 LEU B CG 1 ATOM 4681 C CD1 . LEU B 1 216 ? -9.224 -32.188 -48.706 1.00 40.15 ? 216 LEU B CD1 1 ATOM 4682 C CD2 . LEU B 1 216 ? -11.130 -32.927 -47.297 1.00 40.54 ? 216 LEU B CD2 1 ATOM 4683 N N . PRO B 1 217 ? -14.098 -29.218 -48.232 1.00 42.05 ? 217 PRO B N 1 ATOM 4684 C CA . PRO B 1 217 ? -14.661 -27.857 -48.316 1.00 40.48 ? 217 PRO B CA 1 ATOM 4685 C C . PRO B 1 217 ? -13.581 -26.771 -48.459 1.00 44.65 ? 217 PRO B C 1 ATOM 4686 O O . PRO B 1 217 ? -13.452 -25.951 -47.549 1.00 46.40 ? 217 PRO B O 1 ATOM 4687 C CB . PRO B 1 217 ? -15.352 -27.722 -46.957 1.00 41.73 ? 217 PRO B CB 1 ATOM 4688 C CG . PRO B 1 217 ? -14.485 -28.516 -46.012 1.00 46.41 ? 217 PRO B CG 1 ATOM 4689 C CD . PRO B 1 217 ? -14.150 -29.733 -46.838 1.00 43.04 ? 217 PRO B CD 1 ATOM 4690 N N . LEU B 1 218 ? -12.792 -26.754 -49.545 1.00 39.58 ? 218 LEU B N 1 ATOM 4691 C CA . LEU B 1 218 ? -11.738 -25.738 -49.684 1.00 40.11 ? 218 LEU B CA 1 ATOM 4692 C C . LEU B 1 218 ? -11.644 -25.181 -51.117 1.00 48.57 ? 218 LEU B C 1 ATOM 4693 O O . LEU B 1 218 ? -12.080 -25.883 -52.047 1.00 51.56 ? 218 LEU B O 1 ATOM 4694 C CB . LEU B 1 218 ? -10.365 -26.311 -49.275 1.00 39.81 ? 218 LEU B CB 1 ATOM 4695 C CG . LEU B 1 218 ? -10.145 -26.803 -47.855 1.00 42.79 ? 218 LEU B CG 1 ATOM 4696 C CD1 . LEU B 1 218 ? -8.885 -27.583 -47.787 1.00 42.14 ? 218 LEU B CD1 1 ATOM 4697 C CD2 . LEU B 1 218 ? -10.111 -25.656 -46.864 1.00 43.70 ? 218 LEU B CD2 1 ATOM 4698 N N . PRO B 1 219 ? -11.052 -23.971 -51.350 1.00 43.49 ? 219 PRO B N 1 ATOM 4699 C CA . PRO B 1 219 ? -10.924 -23.487 -52.735 1.00 43.49 ? 219 PRO B CA 1 ATOM 4700 C C . PRO B 1 219 ? -9.967 -24.387 -53.527 1.00 49.55 ? 219 PRO B C 1 ATOM 4701 O O . PRO B 1 219 ? -9.006 -24.877 -52.952 1.00 49.00 ? 219 PRO B O 1 ATOM 4702 C CB . PRO B 1 219 ? -10.395 -22.054 -52.566 1.00 44.79 ? 219 PRO B CB 1 ATOM 4703 C CG . PRO B 1 219 ? -10.673 -21.702 -51.114 1.00 48.61 ? 219 PRO B CG 1 ATOM 4704 C CD . PRO B 1 219 ? -10.472 -22.997 -50.406 1.00 44.29 ? 219 PRO B CD 1 ATOM 4705 N N . TRP B 1 220 ? -10.253 -24.667 -54.809 1.00 48.20 ? 220 TRP B N 1 ATOM 4706 C CA . TRP B 1 220 ? -9.408 -25.564 -55.603 1.00 48.95 ? 220 TRP B CA 1 ATOM 4707 C C . TRP B 1 220 ? -9.185 -25.138 -57.048 1.00 55.74 ? 220 TRP B C 1 ATOM 4708 O O . TRP B 1 220 ? -9.859 -24.241 -57.538 1.00 54.55 ? 220 TRP B O 1 ATOM 4709 C CB . TRP B 1 220 ? -9.960 -26.986 -55.558 1.00 48.03 ? 220 TRP B CB 1 ATOM 4710 C CG . TRP B 1 220 ? -11.329 -27.120 -56.161 1.00 48.86 ? 220 TRP B CG 1 ATOM 4711 C CD1 . TRP B 1 220 ? -12.520 -26.827 -55.566 1.00 51.79 ? 220 TRP B CD1 1 ATOM 4712 C CD2 . TRP B 1 220 ? -11.643 -27.546 -57.497 1.00 48.36 ? 220 TRP B CD2 1 ATOM 4713 N NE1 . TRP B 1 220 ? -13.558 -27.052 -56.448 1.00 51.07 ? 220 TRP B NE1 1 ATOM 4714 C CE2 . TRP B 1 220 ? -13.050 -27.501 -57.635 1.00 51.46 ? 220 TRP B CE2 1 ATOM 4715 C CE3 . TRP B 1 220 ? -10.871 -27.961 -58.593 1.00 49.30 ? 220 TRP B CE3 1 ATOM 4716 C CZ2 . TRP B 1 220 ? -13.700 -27.887 -58.801 1.00 49.66 ? 220 TRP B CZ2 1 ATOM 4717 C CZ3 . TRP B 1 220 ? -11.524 -28.389 -59.735 1.00 50.25 ? 220 TRP B CZ3 1 ATOM 4718 C CH2 . TRP B 1 220 ? -12.922 -28.345 -59.832 1.00 50.47 ? 220 TRP B CH2 1 ATOM 4719 N N . LEU B 1 221 ? -8.185 -25.752 -57.709 1.00 57.10 ? 221 LEU B N 1 ATOM 4720 C CA . LEU B 1 221 ? -7.821 -25.564 -59.134 1.00 58.84 ? 221 LEU B CA 1 ATOM 4721 C C . LEU B 1 221 ? -7.623 -26.947 -59.760 1.00 67.45 ? 221 LEU B C 1 ATOM 4722 O O . LEU B 1 221 ? -6.963 -27.771 -59.117 1.00 68.88 ? 221 LEU B O 1 ATOM 4723 C CB . LEU B 1 221 ? -6.522 -24.781 -59.311 1.00 58.85 ? 221 LEU B CB 1 ATOM 4724 C CG . LEU B 1 221 ? -6.493 -23.346 -58.843 1.00 63.97 ? 221 LEU B CG 1 ATOM 4725 C CD1 . LEU B 1 221 ? -5.070 -22.894 -58.651 1.00 64.17 ? 221 LEU B CD1 1 ATOM 4726 C CD2 . LEU B 1 221 ? -7.221 -22.430 -59.815 1.00 67.02 ? 221 LEU B CD2 1 ATOM 4727 N N . PRO B 1 222 ? -8.157 -27.246 -60.985 1.00 65.09 ? 222 PRO B N 1 ATOM 4728 C CA . PRO B 1 222 ? -7.988 -28.596 -61.569 1.00 64.44 ? 222 PRO B CA 1 ATOM 4729 C C . PRO B 1 222 ? -6.535 -28.961 -61.770 1.00 68.27 ? 222 PRO B C 1 ATOM 4730 O O . PRO B 1 222 ? -5.692 -28.065 -61.922 1.00 68.91 ? 222 PRO B O 1 ATOM 4731 C CB . PRO B 1 222 ? -8.744 -28.515 -62.891 1.00 65.69 ? 222 PRO B CB 1 ATOM 4732 C CG . PRO B 1 222 ? -9.680 -27.377 -62.719 1.00 70.46 ? 222 PRO B CG 1 ATOM 4733 C CD . PRO B 1 222 ? -8.916 -26.384 -61.907 1.00 66.74 ? 222 PRO B CD 1 ATOM 4734 N N . GLY B 1 223 ? -6.257 -30.263 -61.648 1.00 63.36 ? 223 GLY B N 1 ATOM 4735 C CA . GLY B 1 223 ? -4.917 -30.837 -61.725 1.00 63.33 ? 223 GLY B CA 1 ATOM 4736 C C . GLY B 1 223 ? -4.082 -30.369 -62.894 1.00 66.85 ? 223 GLY B C 1 ATOM 4737 O O . GLY B 1 223 ? -2.880 -30.118 -62.738 1.00 64.73 ? 223 GLY B O 1 ATOM 4738 N N . ALA B 1 224 ? -4.745 -30.246 -64.068 1.00 64.12 ? 224 ALA B N 1 ATOM 4739 C CA . ALA B 1 224 ? -4.200 -29.755 -65.323 1.00 64.75 ? 224 ALA B CA 1 ATOM 4740 C C . ALA B 1 224 ? -3.741 -28.254 -65.262 1.00 69.98 ? 224 ALA B C 1 ATOM 4741 O O . ALA B 1 224 ? -2.698 -27.915 -65.839 1.00 69.03 ? 224 ALA B O 1 ATOM 4742 C CB . ALA B 1 224 ? -5.234 -29.942 -66.411 1.00 65.47 ? 224 ALA B CB 1 ATOM 4743 N N . ASP B 1 225 ? -4.522 -27.379 -64.555 1.00 67.93 ? 225 ASP B N 1 ATOM 4744 C CA . ASP B 1 225 ? -4.256 -25.946 -64.433 1.00 68.69 ? 225 ASP B CA 1 ATOM 4745 C C . ASP B 1 225 ? -3.005 -25.621 -63.611 1.00 76.54 ? 225 ASP B C 1 ATOM 4746 O O . ASP B 1 225 ? -3.012 -25.619 -62.373 1.00 76.74 ? 225 ASP B O 1 ATOM 4747 C CB . ASP B 1 225 ? -5.478 -25.150 -63.922 1.00 70.69 ? 225 ASP B CB 1 ATOM 4748 C CG . ASP B 1 225 ? -5.258 -23.642 -64.041 1.00 80.60 ? 225 ASP B CG 1 ATOM 4749 O OD1 . ASP B 1 225 ? -4.317 -23.243 -64.750 1.00 88.75 ? 225 ASP B OD1 1 ATOM 4750 O OD2 . ASP B 1 225 ? -6.052 -22.857 -63.433 1.00 78.67 ? 225 ASP B OD2 1 ATOM 4751 N N . THR B 1 226 ? -1.938 -25.294 -64.333 1.00 75.73 ? 226 THR B N 1 ATOM 4752 C CA . THR B 1 226 ? -0.640 -24.929 -63.771 1.00 76.54 ? 226 THR B CA 1 ATOM 4753 C C . THR B 1 226 ? -0.499 -23.409 -63.838 1.00 82.08 ? 226 THR B C 1 ATOM 4754 O O . THR B 1 226 ? -0.246 -22.766 -62.817 1.00 82.47 ? 226 THR B O 1 ATOM 4755 C CB . THR B 1 226 ? 0.479 -25.691 -64.511 1.00 86.68 ? 226 THR B CB 1 ATOM 4756 O OG1 . THR B 1 226 ? 0.007 -26.144 -65.790 1.00 82.76 ? 226 THR B OG1 1 ATOM 4757 C CG2 . THR B 1 226 ? 0.997 -26.879 -63.712 1.00 86.79 ? 226 THR B CG2 1 ATOM 4758 N N . GLN B 1 227 ? -0.776 -22.845 -65.036 1.00 78.35 ? 227 GLN B N 1 ATOM 4759 C CA . GLN B 1 227 ? -0.738 -21.424 -65.410 1.00 77.78 ? 227 GLN B CA 1 ATOM 4760 C C . GLN B 1 227 ? -1.666 -20.486 -64.610 1.00 79.46 ? 227 GLN B C 1 ATOM 4761 O O . GLN B 1 227 ? -1.309 -19.341 -64.353 1.00 79.21 ? 227 GLN B O 1 ATOM 4762 C CB . GLN B 1 227 ? -1.066 -21.244 -66.922 1.00 79.39 ? 227 GLN B CB 1 ATOM 4763 C CG . GLN B 1 227 ? -0.626 -22.373 -67.871 1.00 99.98 ? 227 GLN B CG 1 ATOM 4764 C CD . GLN B 1 227 ? -1.776 -23.243 -68.346 1.00 115.88 ? 227 GLN B CD 1 ATOM 4765 O OE1 . GLN B 1 227 ? -2.401 -23.995 -67.578 1.00 108.99 ? 227 GLN B OE1 1 ATOM 4766 N NE2 . GLN B 1 227 ? -2.042 -23.197 -69.643 1.00 105.24 ? 227 GLN B NE2 1 ATOM 4767 N N . GLY B 1 228 ? -2.861 -20.949 -64.296 1.00 75.43 ? 228 GLY B N 1 ATOM 4768 C CA . GLY B 1 228 ? -3.905 -20.137 -63.677 1.00 75.40 ? 228 GLY B CA 1 ATOM 4769 C C . GLY B 1 228 ? -4.028 -20.101 -62.174 1.00 78.63 ? 228 GLY B C 1 ATOM 4770 O O . GLY B 1 228 ? -3.603 -21.030 -61.470 1.00 79.58 ? 228 GLY B O 1 ATOM 4771 N N . SER B 1 229 ? -4.683 -19.018 -61.706 1.00 71.68 ? 229 SER B N 1 ATOM 4772 C CA . SER B 1 229 ? -4.884 -18.643 -60.314 1.00 70.08 ? 229 SER B CA 1 ATOM 4773 C C . SER B 1 229 ? -6.350 -18.254 -60.006 1.00 69.95 ? 229 SER B C 1 ATOM 4774 O O . SER B 1 229 ? -6.591 -17.405 -59.124 1.00 68.96 ? 229 SER B O 1 ATOM 4775 C CB . SER B 1 229 ? -3.975 -17.461 -60.006 1.00 76.08 ? 229 SER B CB 1 ATOM 4776 O OG . SER B 1 229 ? -4.325 -16.357 -60.831 1.00 89.77 ? 229 SER B OG 1 ATOM 4777 N N . ASN B 1 230 ? -7.323 -18.883 -60.731 1.00 63.67 ? 230 ASN B N 1 ATOM 4778 C CA . ASN B 1 230 ? -8.772 -18.641 -60.580 1.00 60.69 ? 230 ASN B CA 1 ATOM 4779 C C . ASN B 1 230 ? -9.379 -19.717 -59.730 1.00 58.46 ? 230 ASN B C 1 ATOM 4780 O O . ASN B 1 230 ? -10.075 -20.593 -60.232 1.00 59.23 ? 230 ASN B O 1 ATOM 4781 C CB . ASN B 1 230 ? -9.496 -18.554 -61.934 1.00 57.30 ? 230 ASN B CB 1 ATOM 4782 C CG . ASN B 1 230 ? -8.949 -17.534 -62.889 1.00 72.90 ? 230 ASN B CG 1 ATOM 4783 O OD1 . ASN B 1 230 ? -8.175 -16.626 -62.518 1.00 65.49 ? 230 ASN B OD1 1 ATOM 4784 N ND2 . ASN B 1 230 ? -9.372 -17.654 -64.148 1.00 63.99 ? 230 ASN B ND2 1 ATOM 4785 N N . TRP B 1 231 ? -9.067 -19.672 -58.445 1.00 50.04 ? 231 TRP B N 1 ATOM 4786 C CA . TRP B 1 231 ? -9.530 -20.603 -57.424 1.00 48.10 ? 231 TRP B CA 1 ATOM 4787 C C . TRP B 1 231 ? -11.056 -20.793 -57.382 1.00 46.97 ? 231 TRP B C 1 ATOM 4788 O O . TRP B 1 231 ? -11.785 -19.844 -57.077 1.00 48.88 ? 231 TRP B O 1 ATOM 4789 C CB . TRP B 1 231 ? -9.016 -20.144 -56.054 1.00 46.93 ? 231 TRP B CB 1 ATOM 4790 C CG . TRP B 1 231 ? -7.539 -20.322 -55.869 1.00 48.40 ? 231 TRP B CG 1 ATOM 4791 C CD1 . TRP B 1 231 ? -6.585 -19.348 -55.870 1.00 51.37 ? 231 TRP B CD1 1 ATOM 4792 C CD2 . TRP B 1 231 ? -6.859 -21.550 -55.606 1.00 48.59 ? 231 TRP B CD2 1 ATOM 4793 N NE1 . TRP B 1 231 ? -5.351 -19.895 -55.618 1.00 50.71 ? 231 TRP B NE1 1 ATOM 4794 C CE2 . TRP B 1 231 ? -5.489 -21.248 -55.459 1.00 52.53 ? 231 TRP B CE2 1 ATOM 4795 C CE3 . TRP B 1 231 ? -7.285 -22.870 -55.406 1.00 50.62 ? 231 TRP B CE3 1 ATOM 4796 C CZ2 . TRP B 1 231 ? -4.537 -22.225 -55.149 1.00 52.86 ? 231 TRP B CZ2 1 ATOM 4797 C CZ3 . TRP B 1 231 ? -6.341 -23.842 -55.122 1.00 53.07 ? 231 TRP B CZ3 1 ATOM 4798 C CH2 . TRP B 1 231 ? -4.981 -23.520 -55.000 1.00 53.88 ? 231 TRP B CH2 1 ATOM 4799 N N . ILE B 1 232 ? -11.533 -22.005 -57.681 1.00 37.27 ? 232 ILE B N 1 ATOM 4800 C CA . ILE B 1 232 ? -12.948 -22.361 -57.573 1.00 37.20 ? 232 ILE B CA 1 ATOM 4801 C C . ILE B 1 232 ? -13.296 -22.441 -56.050 1.00 46.49 ? 232 ILE B C 1 ATOM 4802 O O . ILE B 1 232 ? -12.412 -22.762 -55.267 1.00 46.69 ? 232 ILE B O 1 ATOM 4803 C CB . ILE B 1 232 ? -13.199 -23.724 -58.261 1.00 39.49 ? 232 ILE B CB 1 ATOM 4804 C CG1 . ILE B 1 232 ? -12.873 -23.669 -59.749 1.00 39.94 ? 232 ILE B CG1 1 ATOM 4805 C CG2 . ILE B 1 232 ? -14.613 -24.234 -58.031 1.00 39.16 ? 232 ILE B CG2 1 ATOM 4806 C CD1 . ILE B 1 232 ? -11.895 -24.692 -60.222 1.00 44.21 ? 232 ILE B CD1 1 ATOM 4807 N N . GLN B 1 233 ? -14.548 -22.123 -55.634 1.00 45.34 ? 233 GLN B N 1 ATOM 4808 C CA . GLN B 1 233 ? -15.040 -22.174 -54.244 1.00 45.89 ? 233 GLN B CA 1 ATOM 4809 C C . GLN B 1 233 ? -14.354 -21.224 -53.225 1.00 48.31 ? 233 GLN B C 1 ATOM 4810 O O . GLN B 1 233 ? -14.378 -21.537 -52.046 1.00 48.40 ? 233 GLN B O 1 ATOM 4811 C CB . GLN B 1 233 ? -14.991 -23.619 -53.695 1.00 48.59 ? 233 GLN B CB 1 ATOM 4812 C CG . GLN B 1 233 ? -16.038 -24.573 -54.253 1.00 81.42 ? 233 GLN B CG 1 ATOM 4813 C CD . GLN B 1 233 ? -15.654 -26.043 -54.090 1.00 113.45 ? 233 GLN B CD 1 ATOM 4814 O OE1 . GLN B 1 233 ? -16.055 -26.897 -54.914 1.00 114.25 ? 233 GLN B OE1 1 ATOM 4815 N NE2 . GLN B 1 233 ? -14.872 -26.384 -53.038 1.00 93.78 ? 233 GLN B NE2 1 ATOM 4816 N N . LYS B 1 234 ? -13.802 -20.074 -53.620 1.00 45.34 ? 234 LYS B N 1 ATOM 4817 C CA . LYS B 1 234 ? -13.163 -19.126 -52.669 1.00 45.36 ? 234 LYS B CA 1 ATOM 4818 C C . LYS B 1 234 ? -13.992 -18.901 -51.410 1.00 53.85 ? 234 LYS B C 1 ATOM 4819 O O . LYS B 1 234 ? -13.444 -18.715 -50.330 1.00 53.93 ? 234 LYS B O 1 ATOM 4820 C CB . LYS B 1 234 ? -12.844 -17.762 -53.328 1.00 47.33 ? 234 LYS B CB 1 ATOM 4821 C CG . LYS B 1 234 ? -11.702 -17.821 -54.374 1.00 55.58 ? 234 LYS B CG 1 ATOM 4822 C CD . LYS B 1 234 ? -11.588 -16.648 -55.330 1.00 57.51 ? 234 LYS B CD 1 ATOM 4823 C CE . LYS B 1 234 ? -12.551 -16.711 -56.489 1.00 72.75 ? 234 LYS B CE 1 ATOM 4824 N NZ . LYS B 1 234 ? -11.871 -16.904 -57.783 1.00 77.59 ? 234 LYS B NZ 1 ATOM 4825 N N . GLU B 1 235 ? -15.320 -18.991 -51.560 1.00 55.00 ? 235 GLU B N 1 ATOM 4826 C CA . GLU B 1 235 ? -16.364 -18.871 -50.542 1.00 57.40 ? 235 GLU B CA 1 ATOM 4827 C C . GLU B 1 235 ? -16.106 -19.756 -49.303 1.00 63.52 ? 235 GLU B C 1 ATOM 4828 O O . GLU B 1 235 ? -16.605 -19.462 -48.217 1.00 66.14 ? 235 GLU B O 1 ATOM 4829 C CB . GLU B 1 235 ? -17.713 -19.275 -51.160 1.00 59.78 ? 235 GLU B CB 1 ATOM 4830 C CG . GLU B 1 235 ? -18.131 -18.465 -52.381 1.00 81.74 ? 235 GLU B CG 1 ATOM 4831 C CD . GLU B 1 235 ? -17.633 -18.965 -53.728 1.00 125.64 ? 235 GLU B CD 1 ATOM 4832 O OE1 . GLU B 1 235 ? -17.684 -20.192 -53.977 1.00 135.62 ? 235 GLU B OE1 1 ATOM 4833 O OE2 . GLU B 1 235 ? -17.241 -18.114 -54.558 1.00 125.02 ? 235 GLU B OE2 1 ATOM 4834 N N . THR B 1 236 ? -15.343 -20.838 -49.467 1.00 58.11 ? 236 THR B N 1 ATOM 4835 C CA . THR B 1 236 ? -15.034 -21.763 -48.385 1.00 57.10 ? 236 THR B CA 1 ATOM 4836 C C . THR B 1 236 ? -13.991 -21.176 -47.404 1.00 62.25 ? 236 THR B C 1 ATOM 4837 O O . THR B 1 236 ? -13.881 -21.663 -46.283 1.00 63.54 ? 236 THR B O 1 ATOM 4838 C CB . THR B 1 236 ? -14.651 -23.117 -48.946 1.00 56.13 ? 236 THR B CB 1 ATOM 4839 O OG1 . THR B 1 236 ? -13.471 -22.960 -49.713 1.00 60.50 ? 236 THR B OG1 1 ATOM 4840 C CG2 . THR B 1 236 ? -15.736 -23.719 -49.825 1.00 49.94 ? 236 THR B CG2 1 ATOM 4841 N N . LEU B 1 237 ? -13.265 -20.126 -47.799 1.00 57.59 ? 237 LEU B N 1 ATOM 4842 C CA . LEU B 1 237 ? -12.296 -19.470 -46.914 1.00 57.73 ? 237 LEU B CA 1 ATOM 4843 C C . LEU B 1 237 ? -12.663 -18.002 -46.687 1.00 67.37 ? 237 LEU B C 1 ATOM 4844 O O . LEU B 1 237 ? -12.016 -17.300 -45.891 1.00 66.43 ? 237 LEU B O 1 ATOM 4845 C CB . LEU B 1 237 ? -10.862 -19.540 -47.471 1.00 56.70 ? 237 LEU B CB 1 ATOM 4846 C CG . LEU B 1 237 ? -10.085 -20.839 -47.396 1.00 58.56 ? 237 LEU B CG 1 ATOM 4847 C CD1 . LEU B 1 237 ? -8.618 -20.569 -47.404 1.00 56.00 ? 237 LEU B CD1 1 ATOM 4848 C CD2 . LEU B 1 237 ? -10.406 -21.611 -46.159 1.00 60.90 ? 237 LEU B CD2 1 ATOM 4849 N N . VAL B 1 238 ? -13.671 -17.524 -47.438 1.00 67.38 ? 238 VAL B N 1 ATOM 4850 C CA . VAL B 1 238 ? -14.093 -16.133 -47.363 1.00 67.76 ? 238 VAL B CA 1 ATOM 4851 C C . VAL B 1 238 ? -15.454 -16.063 -46.693 1.00 74.91 ? 238 VAL B C 1 ATOM 4852 O O . VAL B 1 238 ? -16.310 -16.926 -46.916 1.00 74.29 ? 238 VAL B O 1 ATOM 4853 C CB . VAL B 1 238 ? -14.030 -15.432 -48.751 1.00 70.34 ? 238 VAL B CB 1 ATOM 4854 C CG1 . VAL B 1 238 ? -14.189 -13.948 -48.612 1.00 69.73 ? 238 VAL B CG1 1 ATOM 4855 C CG2 . VAL B 1 238 ? -12.723 -15.722 -49.475 1.00 69.92 ? 238 VAL B CG2 1 ATOM 4856 N N . THR B 1 239 ? -15.646 -15.035 -45.854 1.00 74.47 ? 239 THR B N 1 ATOM 4857 C CA . THR B 1 239 ? -16.899 -14.790 -45.129 1.00 74.82 ? 239 THR B CA 1 ATOM 4858 C C . THR B 1 239 ? -17.291 -13.314 -45.237 1.00 75.48 ? 239 THR B C 1 ATOM 4859 O O . THR B 1 239 ? -16.462 -12.436 -44.981 1.00 73.82 ? 239 THR B O 1 ATOM 4860 C CB . THR B 1 239 ? -16.762 -15.274 -43.669 1.00 92.22 ? 239 THR B CB 1 ATOM 4861 O OG1 . THR B 1 239 ? -16.388 -16.651 -43.686 1.00 99.59 ? 239 THR B OG1 1 ATOM 4862 C CG2 . THR B 1 239 ? -18.040 -15.118 -42.859 1.00 91.71 ? 239 THR B CG2 1 ATOM 4863 N N . PHE B 1 240 ? -18.554 -13.050 -45.620 1.00 71.31 ? 240 PHE B N 1 ATOM 4864 C CA . PHE B 1 240 ? -19.087 -11.696 -45.691 1.00 71.27 ? 240 PHE B CA 1 ATOM 4865 C C . PHE B 1 240 ? -20.011 -11.485 -44.485 1.00 81.74 ? 240 PHE B C 1 ATOM 4866 O O . PHE B 1 240 ? -20.911 -12.302 -44.247 1.00 81.56 ? 240 PHE B O 1 ATOM 4867 C CB . PHE B 1 240 ? -19.803 -11.466 -47.024 1.00 71.63 ? 240 PHE B CB 1 ATOM 4868 C CG . PHE B 1 240 ? -18.883 -11.425 -48.226 1.00 71.46 ? 240 PHE B CG 1 ATOM 4869 C CD1 . PHE B 1 240 ? -18.569 -12.582 -48.927 1.00 72.58 ? 240 PHE B CD1 1 ATOM 4870 C CD2 . PHE B 1 240 ? -18.330 -10.235 -48.656 1.00 72.48 ? 240 PHE B CD2 1 ATOM 4871 C CE1 . PHE B 1 240 ? -17.714 -12.544 -50.037 1.00 72.54 ? 240 PHE B CE1 1 ATOM 4872 C CE2 . PHE B 1 240 ? -17.484 -10.199 -49.776 1.00 74.46 ? 240 PHE B CE2 1 ATOM 4873 C CZ . PHE B 1 240 ? -17.183 -11.351 -50.459 1.00 71.74 ? 240 PHE B CZ 1 ATOM 4874 N N . LYS B 1 241 ? -19.720 -10.446 -43.662 1.00 83.07 ? 241 LYS B N 1 ATOM 4875 C CA . LYS B 1 241 ? -20.464 -10.154 -42.433 1.00 85.29 ? 241 LYS B CA 1 ATOM 4876 C C . LYS B 1 241 ? -21.253 -8.858 -42.473 1.00 92.62 ? 241 LYS B C 1 ATOM 4877 O O . LYS B 1 241 ? -20.689 -7.768 -42.607 1.00 91.96 ? 241 LYS B O 1 ATOM 4878 C CB . LYS B 1 241 ? -19.568 -10.169 -41.177 1.00 88.72 ? 241 LYS B CB 1 ATOM 4879 C CG . LYS B 1 241 ? -18.929 -11.487 -40.839 1.00 101.82 ? 241 LYS B CG 1 ATOM 4880 C CD . LYS B 1 241 ? -17.932 -11.315 -39.689 1.00 111.37 ? 241 LYS B CD 1 ATOM 4881 C CE . LYS B 1 241 ? -17.479 -12.660 -39.194 1.00 124.05 ? 241 LYS B CE 1 ATOM 4882 N NZ . LYS B 1 241 ? -16.518 -12.546 -38.066 1.00 132.24 ? 241 LYS B NZ 1 ATOM 4883 N N . ASN B 1 242 ? -22.577 -8.990 -42.319 1.00 92.27 ? 242 ASN B N 1 ATOM 4884 C CA . ASN B 1 242 ? -23.521 -7.884 -42.297 1.00 94.00 ? 242 ASN B CA 1 ATOM 4885 C C . ASN B 1 242 ? -24.596 -8.211 -41.239 1.00 101.31 ? 242 ASN B C 1 ATOM 4886 O O . ASN B 1 242 ? -25.698 -8.660 -41.589 1.00 101.64 ? 242 ASN B O 1 ATOM 4887 C CB . ASN B 1 242 ? -24.123 -7.666 -43.695 1.00 94.76 ? 242 ASN B CB 1 ATOM 4888 C CG . ASN B 1 242 ? -24.958 -6.422 -43.815 1.00 99.68 ? 242 ASN B CG 1 ATOM 4889 O OD1 . ASN B 1 242 ? -25.032 -5.591 -42.902 1.00 93.50 ? 242 ASN B OD1 1 ATOM 4890 N ND2 . ASN B 1 242 ? -25.584 -6.260 -44.966 1.00 82.07 ? 242 ASN B ND2 1 ATOM 4891 N N . PRO B 1 243 ? -24.279 -8.021 -39.932 1.00 98.70 ? 243 PRO B N 1 ATOM 4892 C CA . PRO B 1 243 ? -25.241 -8.421 -38.889 1.00 98.72 ? 243 PRO B CA 1 ATOM 4893 C C . PRO B 1 243 ? -26.350 -7.432 -38.560 1.00 104.01 ? 243 PRO B C 1 ATOM 4894 O O . PRO B 1 243 ? -27.370 -7.838 -37.999 1.00 103.47 ? 243 PRO B O 1 ATOM 4895 C CB . PRO B 1 243 ? -24.351 -8.670 -37.672 1.00 100.32 ? 243 PRO B CB 1 ATOM 4896 C CG . PRO B 1 243 ? -23.183 -7.747 -37.863 1.00 104.77 ? 243 PRO B CG 1 ATOM 4897 C CD . PRO B 1 243 ? -23.007 -7.536 -39.345 1.00 100.28 ? 243 PRO B CD 1 ATOM 4898 N N . HIS B 1 244 ? -26.140 -6.139 -38.845 1.00 101.43 ? 244 HIS B N 1 ATOM 4899 C CA . HIS B 1 244 ? -27.124 -5.122 -38.473 1.00 101.01 ? 244 HIS B CA 1 ATOM 4900 C C . HIS B 1 244 ? -27.644 -4.301 -39.658 1.00 101.37 ? 244 HIS B C 1 ATOM 4901 O O . HIS B 1 244 ? -28.324 -3.293 -39.450 1.00 100.75 ? 244 HIS B O 1 ATOM 4902 C CB . HIS B 1 244 ? -26.552 -4.211 -37.361 1.00 102.08 ? 244 HIS B CB 1 ATOM 4903 C CG . HIS B 1 244 ? -25.966 -4.951 -36.197 1.00 105.87 ? 244 HIS B CG 1 ATOM 4904 N ND1 . HIS B 1 244 ? -26.723 -5.845 -35.451 1.00 107.85 ? 244 HIS B ND1 1 ATOM 4905 C CD2 . HIS B 1 244 ? -24.716 -4.894 -35.678 1.00 108.02 ? 244 HIS B CD2 1 ATOM 4906 C CE1 . HIS B 1 244 ? -25.910 -6.298 -34.508 1.00 107.55 ? 244 HIS B CE1 1 ATOM 4907 N NE2 . HIS B 1 244 ? -24.692 -5.753 -34.603 1.00 107.87 ? 244 HIS B NE2 1 ATOM 4908 N N . ALA B 1 245 ? -27.357 -4.755 -40.898 1.00 94.57 ? 245 ALA B N 1 ATOM 4909 C CA . ALA B 1 245 ? -27.715 -4.081 -42.143 1.00 92.66 ? 245 ALA B CA 1 ATOM 4910 C C . ALA B 1 245 ? -27.135 -2.650 -42.172 1.00 94.96 ? 245 ALA B C 1 ATOM 4911 O O . ALA B 1 245 ? -27.705 -1.768 -42.782 1.00 93.91 ? 245 ALA B O 1 ATOM 4912 C CB . ALA B 1 245 ? -29.225 -4.101 -42.368 1.00 92.87 ? 245 ALA B CB 1 ATOM 4913 N N . LYS B 1 246 ? -25.978 -2.438 -41.515 1.00 91.75 ? 246 LYS B N 1 ATOM 4914 C CA . LYS B 1 246 ? -25.292 -1.141 -41.447 1.00 91.86 ? 246 LYS B CA 1 ATOM 4915 C C . LYS B 1 246 ? -24.067 -1.117 -42.375 1.00 97.05 ? 246 LYS B C 1 ATOM 4916 O O . LYS B 1 246 ? -23.735 -0.065 -42.938 1.00 97.95 ? 246 LYS B O 1 ATOM 4917 C CB . LYS B 1 246 ? -24.886 -0.801 -39.992 1.00 93.92 ? 246 LYS B CB 1 ATOM 4918 C CG . LYS B 1 246 ? -26.071 -0.781 -39.005 1.00 107.67 ? 246 LYS B CG 1 ATOM 4919 C CD . LYS B 1 246 ? -25.681 -0.385 -37.579 1.00 116.49 ? 246 LYS B CD 1 ATOM 4920 C CE . LYS B 1 246 ? -26.862 -0.361 -36.629 1.00 122.77 ? 246 LYS B CE 1 ATOM 4921 N NZ . LYS B 1 246 ? -26.492 0.176 -35.287 1.00 131.90 ? 246 LYS B NZ 1 ATOM 4922 N N . LYS B 1 247 ? -23.412 -2.290 -42.549 1.00 92.15 ? 247 LYS B N 1 ATOM 4923 C CA . LYS B 1 247 ? -22.207 -2.464 -43.365 1.00 90.66 ? 247 LYS B CA 1 ATOM 4924 C C . LYS B 1 247 ? -21.899 -3.944 -43.658 1.00 92.58 ? 247 LYS B C 1 ATOM 4925 O O . LYS B 1 247 ? -22.261 -4.819 -42.879 1.00 89.96 ? 247 LYS B O 1 ATOM 4926 C CB . LYS B 1 247 ? -20.973 -1.772 -42.696 1.00 92.03 ? 247 LYS B CB 1 ATOM 4927 C CG . LYS B 1 247 ? -20.895 -1.896 -41.169 1.00 96.70 ? 247 LYS B CG 1 ATOM 4928 C CD . LYS B 1 247 ? -19.487 -2.089 -40.622 1.00 106.01 ? 247 LYS B CD 1 ATOM 4929 C CE . LYS B 1 247 ? -19.542 -2.808 -39.284 1.00 121.21 ? 247 LYS B CE 1 ATOM 4930 N NZ . LYS B 1 247 ? -18.223 -3.363 -38.868 1.00 128.66 ? 247 LYS B NZ 1 ATOM 4931 N N . GLN B 1 248 ? -21.209 -4.211 -44.790 1.00 90.31 ? 248 GLN B N 1 ATOM 4932 C CA . GLN B 1 248 ? -20.733 -5.542 -45.190 1.00 89.93 ? 248 GLN B CA 1 ATOM 4933 C C . GLN B 1 248 ? -19.204 -5.615 -45.051 1.00 96.47 ? 248 GLN B C 1 ATOM 4934 O O . GLN B 1 248 ? -18.470 -4.832 -45.671 1.00 96.00 ? 248 GLN B O 1 ATOM 4935 C CB . GLN B 1 248 ? -21.167 -5.926 -46.609 1.00 90.35 ? 248 GLN B CB 1 ATOM 4936 C CG . GLN B 1 248 ? -21.010 -7.418 -46.852 1.00 87.89 ? 248 GLN B CG 1 ATOM 4937 C CD . GLN B 1 248 ? -21.803 -7.950 -48.025 1.00 92.30 ? 248 GLN B CD 1 ATOM 4938 O OE1 . GLN B 1 248 ? -22.589 -8.902 -47.883 1.00 79.58 ? 248 GLN B OE1 1 ATOM 4939 N NE2 . GLN B 1 248 ? -21.558 -7.413 -49.222 1.00 77.10 ? 248 GLN B NE2 1 ATOM 4940 N N . ASP B 1 249 ? -18.738 -6.559 -44.213 1.00 95.02 ? 249 ASP B N 1 ATOM 4941 C CA . ASP B 1 249 ? -17.314 -6.806 -43.941 1.00 94.88 ? 249 ASP B CA 1 ATOM 4942 C C . ASP B 1 249 ? -16.827 -8.124 -44.512 1.00 95.48 ? 249 ASP B C 1 ATOM 4943 O O . ASP B 1 249 ? -17.537 -9.118 -44.428 1.00 93.97 ? 249 ASP B O 1 ATOM 4944 C CB . ASP B 1 249 ? -17.031 -6.705 -42.437 1.00 97.49 ? 249 ASP B CB 1 ATOM 4945 C CG . ASP B 1 249 ? -16.941 -5.267 -41.974 1.00 112.94 ? 249 ASP B CG 1 ATOM 4946 O OD1 . ASP B 1 249 ? -17.915 -4.513 -42.193 1.00 113.94 ? 249 ASP B OD1 1 ATOM 4947 O OD2 . ASP B 1 249 ? -15.877 -4.884 -41.425 1.00 120.14 ? 249 ASP B OD2 1 ATOM 4948 N N . VAL B 1 250 ? -15.631 -8.126 -45.116 1.00 90.51 ? 250 VAL B N 1 ATOM 4949 C CA . VAL B 1 250 ? -15.081 -9.337 -45.722 1.00 89.73 ? 250 VAL B CA 1 ATOM 4950 C C . VAL B 1 250 ? -13.912 -9.914 -44.863 1.00 93.99 ? 250 VAL B C 1 ATOM 4951 O O . VAL B 1 250 ? -12.901 -9.237 -44.610 1.00 92.64 ? 250 VAL B O 1 ATOM 4952 C CB . VAL B 1 250 ? -14.736 -9.114 -47.218 1.00 92.48 ? 250 VAL B CB 1 ATOM 4953 C CG1 . VAL B 1 250 ? -13.585 -8.131 -47.413 1.00 91.99 ? 250 VAL B CG1 1 ATOM 4954 C CG2 . VAL B 1 250 ? -14.484 -10.422 -47.942 1.00 91.91 ? 250 VAL B CG2 1 ATOM 4955 N N . VAL B 1 251 ? -14.073 -11.180 -44.424 1.00 90.71 ? 251 VAL B N 1 ATOM 4956 C CA . VAL B 1 251 ? -13.105 -11.849 -43.541 1.00 89.97 ? 251 VAL B CA 1 ATOM 4957 C C . VAL B 1 251 ? -12.560 -13.242 -44.061 1.00 90.05 ? 251 VAL B C 1 ATOM 4958 O O . VAL B 1 251 ? -13.319 -14.129 -44.480 1.00 88.54 ? 251 VAL B O 1 ATOM 4959 C CB . VAL B 1 251 ? -13.698 -11.944 -42.107 1.00 94.13 ? 251 VAL B CB 1 ATOM 4960 C CG1 . VAL B 1 251 ? -15.038 -12.680 -42.067 1.00 94.08 ? 251 VAL B CG1 1 ATOM 4961 C CG2 . VAL B 1 251 ? -12.701 -12.476 -41.076 1.00 93.88 ? 251 VAL B CG2 1 ATOM 4962 N N . VAL B 1 252 ? -11.214 -13.403 -43.969 1.00 84.72 ? 252 VAL B N 1 ATOM 4963 C CA . VAL B 1 252 ? -10.457 -14.624 -44.288 1.00 83.79 ? 252 VAL B CA 1 ATOM 4964 C C . VAL B 1 252 ? -10.723 -15.642 -43.166 1.00 84.71 ? 252 VAL B C 1 ATOM 4965 O O . VAL B 1 252 ? -10.870 -15.237 -42.014 1.00 84.26 ? 252 VAL B O 1 ATOM 4966 C CB . VAL B 1 252 ? -8.948 -14.365 -44.440 1.00 87.97 ? 252 VAL B CB 1 ATOM 4967 C CG1 . VAL B 1 252 ? -8.322 -15.427 -45.336 1.00 87.90 ? 252 VAL B CG1 1 ATOM 4968 C CG2 . VAL B 1 252 ? -8.662 -12.955 -44.984 1.00 87.77 ? 252 VAL B CG2 1 ATOM 4969 N N . LEU B 1 253 ? -10.784 -16.941 -43.487 1.00 78.62 ? 253 LEU B N 1 ATOM 4970 C CA . LEU B 1 253 ? -11.163 -17.935 -42.502 1.00 76.91 ? 253 LEU B CA 1 ATOM 4971 C C . LEU B 1 253 ? -10.023 -18.557 -41.687 1.00 80.20 ? 253 LEU B C 1 ATOM 4972 O O . LEU B 1 253 ? -10.304 -19.397 -40.831 1.00 81.52 ? 253 LEU B O 1 ATOM 4973 C CB . LEU B 1 253 ? -12.017 -19.022 -43.141 1.00 76.48 ? 253 LEU B CB 1 ATOM 4974 C CG . LEU B 1 253 ? -13.378 -19.279 -42.502 1.00 80.63 ? 253 LEU B CG 1 ATOM 4975 C CD1 . LEU B 1 253 ? -13.923 -18.037 -41.800 1.00 83.09 ? 253 LEU B CD1 1 ATOM 4976 C CD2 . LEU B 1 253 ? -14.387 -19.732 -43.547 1.00 80.10 ? 253 LEU B CD2 1 ATOM 4977 N N . GLY B 1 254 ? -8.778 -18.126 -41.882 1.00 73.34 ? 254 GLY B N 1 ATOM 4978 C CA . GLY B 1 254 ? -7.668 -18.643 -41.078 1.00 70.61 ? 254 GLY B CA 1 ATOM 4979 C C . GLY B 1 254 ? -7.128 -19.969 -41.556 1.00 68.51 ? 254 GLY B C 1 ATOM 4980 O O . GLY B 1 254 ? -7.900 -20.836 -41.972 1.00 68.98 ? 254 GLY B O 1 ATOM 4981 N N . SER B 1 255 ? -5.798 -20.137 -41.495 1.00 60.40 ? 255 SER B N 1 ATOM 4982 C CA . SER B 1 255 ? -5.095 -21.306 -41.998 1.00 58.40 ? 255 SER B CA 1 ATOM 4983 C C . SER B 1 255 ? -5.707 -22.596 -41.582 1.00 62.73 ? 255 SER B C 1 ATOM 4984 O O . SER B 1 255 ? -6.063 -22.783 -40.416 1.00 62.14 ? 255 SER B O 1 ATOM 4985 C CB . SER B 1 255 ? -3.625 -21.267 -41.634 1.00 60.30 ? 255 SER B CB 1 ATOM 4986 O OG . SER B 1 255 ? -2.937 -22.261 -42.372 1.00 68.49 ? 255 SER B OG 1 ATOM 4987 N N . GLN B 1 256 ? -5.870 -23.476 -42.575 1.00 59.72 ? 256 GLN B N 1 ATOM 4988 C CA . GLN B 1 256 ? -6.472 -24.808 -42.466 1.00 58.03 ? 256 GLN B CA 1 ATOM 4989 C C . GLN B 1 256 ? -5.410 -25.920 -42.413 1.00 58.81 ? 256 GLN B C 1 ATOM 4990 O O . GLN B 1 256 ? -5.749 -27.100 -42.523 1.00 58.58 ? 256 GLN B O 1 ATOM 4991 C CB . GLN B 1 256 ? -7.424 -25.009 -43.654 1.00 58.62 ? 256 GLN B CB 1 ATOM 4992 C CG . GLN B 1 256 ? -8.648 -24.102 -43.599 1.00 52.59 ? 256 GLN B CG 1 ATOM 4993 C CD . GLN B 1 256 ? -9.482 -24.257 -42.343 1.00 67.45 ? 256 GLN B CD 1 ATOM 4994 O OE1 . GLN B 1 256 ? -9.697 -23.299 -41.603 1.00 66.42 ? 256 GLN B OE1 1 ATOM 4995 N NE2 . GLN B 1 256 ? -9.993 -25.458 -42.083 1.00 52.10 ? 256 GLN B NE2 1 ATOM 4996 N N . GLU B 1 257 ? -4.134 -25.539 -42.237 1.00 52.33 ? 257 GLU B N 1 ATOM 4997 C CA . GLU B 1 257 ? -3.001 -26.456 -42.197 1.00 50.25 ? 257 GLU B CA 1 ATOM 4998 C C . GLU B 1 257 ? -3.132 -27.498 -41.091 1.00 51.93 ? 257 GLU B C 1 ATOM 4999 O O . GLU B 1 257 ? -3.152 -28.695 -41.395 1.00 51.70 ? 257 GLU B O 1 ATOM 5000 C CB . GLU B 1 257 ? -1.694 -25.673 -42.081 1.00 51.20 ? 257 GLU B CB 1 ATOM 5001 C CG . GLU B 1 257 ? -0.468 -26.529 -42.249 1.00 62.83 ? 257 GLU B CG 1 ATOM 5002 C CD . GLU B 1 257 ? 0.824 -25.757 -42.136 1.00 101.59 ? 257 GLU B CD 1 ATOM 5003 O OE1 . GLU B 1 257 ? 0.852 -24.732 -41.414 1.00 98.59 ? 257 GLU B OE1 1 ATOM 5004 O OE2 . GLU B 1 257 ? 1.806 -26.164 -42.799 1.00 109.86 ? 257 GLU B OE2 1 ATOM 5005 N N . GLY B 1 258 ? -3.249 -27.033 -39.846 1.00 46.92 ? 258 GLY B N 1 ATOM 5006 C CA . GLY B 1 258 ? -3.389 -27.864 -38.660 1.00 46.35 ? 258 GLY B CA 1 ATOM 5007 C C . GLY B 1 258 ? -4.709 -28.588 -38.641 1.00 49.58 ? 258 GLY B C 1 ATOM 5008 O O . GLY B 1 258 ? -4.793 -29.740 -38.206 1.00 49.05 ? 258 GLY B O 1 ATOM 5009 N N . ALA B 1 259 ? -5.735 -27.914 -39.139 1.00 47.28 ? 259 ALA B N 1 ATOM 5010 C CA . ALA B 1 259 ? -7.085 -28.453 -39.253 1.00 48.50 ? 259 ALA B CA 1 ATOM 5011 C C . ALA B 1 259 ? -7.032 -29.733 -40.111 1.00 53.08 ? 259 ALA B C 1 ATOM 5012 O O . ALA B 1 259 ? -7.526 -30.791 -39.679 1.00 52.59 ? 259 ALA B O 1 ATOM 5013 C CB . ALA B 1 259 ? -7.982 -27.420 -39.902 1.00 49.70 ? 259 ALA B CB 1 ATOM 5014 N N . MET B 1 260 ? -6.354 -29.633 -41.294 1.00 48.39 ? 260 MET B N 1 ATOM 5015 C CA . MET B 1 260 ? -6.109 -30.718 -42.229 1.00 47.13 ? 260 MET B CA 1 ATOM 5016 C C . MET B 1 260 ? -5.350 -31.857 -41.556 1.00 53.81 ? 260 MET B C 1 ATOM 5017 O O . MET B 1 260 ? -5.829 -32.983 -41.660 1.00 53.83 ? 260 MET B O 1 ATOM 5018 C CB . MET B 1 260 ? -5.336 -30.229 -43.453 1.00 48.67 ? 260 MET B CB 1 ATOM 5019 C CG . MET B 1 260 ? -6.204 -29.792 -44.602 1.00 52.02 ? 260 MET B CG 1 ATOM 5020 S SD . MET B 1 260 ? -7.544 -30.921 -45.101 1.00 56.44 ? 260 MET B SD 1 ATOM 5021 C CE . MET B 1 260 ? -6.626 -32.255 -45.864 1.00 53.65 ? 260 MET B CE 1 ATOM 5022 N N . HIS B 1 261 ? -4.204 -31.576 -40.830 1.00 50.20 ? 261 HIS B N 1 ATOM 5023 C CA . HIS B 1 261 ? -3.416 -32.599 -40.117 1.00 49.78 ? 261 HIS B CA 1 ATOM 5024 C C . HIS B 1 261 ? -4.279 -33.414 -39.174 1.00 53.90 ? 261 HIS B C 1 ATOM 5025 O O . HIS B 1 261 ? -4.161 -34.637 -39.161 1.00 55.58 ? 261 HIS B O 1 ATOM 5026 C CB . HIS B 1 261 ? -2.237 -32.006 -39.336 1.00 50.94 ? 261 HIS B CB 1 ATOM 5027 C CG . HIS B 1 261 ? -1.197 -31.299 -40.154 1.00 55.08 ? 261 HIS B CG 1 ATOM 5028 N ND1 . HIS B 1 261 ? -0.394 -30.319 -39.593 1.00 57.36 ? 261 HIS B ND1 1 ATOM 5029 C CD2 . HIS B 1 261 ? -0.844 -31.458 -41.456 1.00 57.76 ? 261 HIS B CD2 1 ATOM 5030 C CE1 . HIS B 1 261 ? 0.406 -29.900 -40.568 1.00 57.56 ? 261 HIS B CE1 1 ATOM 5031 N NE2 . HIS B 1 261 ? 0.179 -30.560 -41.710 1.00 57.75 ? 261 HIS B NE2 1 ATOM 5032 N N . THR B 1 262 ? -5.176 -32.748 -38.422 1.00 49.04 ? 262 THR B N 1 ATOM 5033 C CA . THR B 1 262 ? -6.098 -33.396 -37.488 1.00 48.99 ? 262 THR B CA 1 ATOM 5034 C C . THR B 1 262 ? -7.077 -34.294 -38.228 1.00 56.34 ? 262 THR B C 1 ATOM 5035 O O . THR B 1 262 ? -7.354 -35.402 -37.771 1.00 56.69 ? 262 THR B O 1 ATOM 5036 C CB . THR B 1 262 ? -6.830 -32.340 -36.667 1.00 53.42 ? 262 THR B CB 1 ATOM 5037 O OG1 . THR B 1 262 ? -5.868 -31.535 -35.995 1.00 59.37 ? 262 THR B OG1 1 ATOM 5038 C CG2 . THR B 1 262 ? -7.811 -32.941 -35.670 1.00 46.80 ? 262 THR B CG2 1 ATOM 5039 N N . ALA B 1 263 ? -7.611 -33.808 -39.372 1.00 54.47 ? 263 ALA B N 1 ATOM 5040 C CA . ALA B 1 263 ? -8.560 -34.557 -40.200 1.00 54.33 ? 263 ALA B CA 1 ATOM 5041 C C . ALA B 1 263 ? -7.901 -35.802 -40.782 1.00 58.69 ? 263 ALA B C 1 ATOM 5042 O O . ALA B 1 263 ? -8.566 -36.811 -40.961 1.00 60.41 ? 263 ALA B O 1 ATOM 5043 C CB . ALA B 1 263 ? -9.057 -33.671 -41.327 1.00 55.04 ? 263 ALA B CB 1 ATOM 5044 N N . LEU B 1 264 ? -6.588 -35.717 -41.063 1.00 52.26 ? 264 LEU B N 1 ATOM 5045 C CA . LEU B 1 264 ? -5.791 -36.760 -41.672 1.00 50.48 ? 264 LEU B CA 1 ATOM 5046 C C . LEU B 1 264 ? -5.206 -37.711 -40.632 1.00 54.58 ? 264 LEU B C 1 ATOM 5047 O O . LEU B 1 264 ? -4.269 -38.457 -40.971 1.00 54.15 ? 264 LEU B O 1 ATOM 5048 C CB . LEU B 1 264 ? -4.642 -36.094 -42.456 1.00 49.68 ? 264 LEU B CB 1 ATOM 5049 C CG . LEU B 1 264 ? -4.970 -35.279 -43.682 1.00 51.65 ? 264 LEU B CG 1 ATOM 5050 C CD1 . LEU B 1 264 ? -3.808 -34.340 -44.026 1.00 50.26 ? 264 LEU B CD1 1 ATOM 5051 C CD2 . LEU B 1 264 ? -5.349 -36.175 -44.836 1.00 52.35 ? 264 LEU B CD2 1 ATOM 5052 N N . THR B 1 265 ? -5.736 -37.711 -39.385 1.00 51.00 ? 265 THR B N 1 ATOM 5053 C CA . THR B 1 265 ? -5.149 -38.576 -38.358 1.00 52.08 ? 265 THR B CA 1 ATOM 5054 C C . THR B 1 265 ? -5.376 -40.068 -38.660 1.00 58.01 ? 265 THR B C 1 ATOM 5055 O O . THR B 1 265 ? -4.379 -40.809 -38.788 1.00 58.61 ? 265 THR B O 1 ATOM 5056 C CB . THR B 1 265 ? -5.510 -38.177 -36.955 1.00 64.13 ? 265 THR B CB 1 ATOM 5057 O OG1 . THR B 1 265 ? -6.909 -37.910 -36.858 1.00 75.65 ? 265 THR B OG1 1 ATOM 5058 C CG2 . THR B 1 265 ? -4.670 -36.996 -36.474 1.00 58.39 ? 265 THR B CG2 1 ATOM 5059 N N . GLY B 1 266 ? -6.623 -40.475 -38.884 1.00 54.33 ? 266 GLY B N 1 ATOM 5060 C CA . GLY B 1 266 ? -6.890 -41.877 -39.222 1.00 54.54 ? 266 GLY B CA 1 ATOM 5061 C C . GLY B 1 266 ? -6.265 -42.426 -40.509 1.00 57.69 ? 266 GLY B C 1 ATOM 5062 O O . GLY B 1 266 ? -6.131 -43.643 -40.665 1.00 55.86 ? 266 GLY B O 1 ATOM 5063 N N . ALA B 1 267 ? -5.867 -41.528 -41.431 1.00 55.63 ? 267 ALA B N 1 ATOM 5064 C CA . ALA B 1 267 ? -5.327 -41.821 -42.761 1.00 56.54 ? 267 ALA B CA 1 ATOM 5065 C C . ALA B 1 267 ? -3.947 -42.449 -42.799 1.00 59.36 ? 267 ALA B C 1 ATOM 5066 O O . ALA B 1 267 ? -3.155 -42.281 -41.857 1.00 60.53 ? 267 ALA B O 1 ATOM 5067 C CB . ALA B 1 267 ? -5.317 -40.559 -43.598 1.00 57.92 ? 267 ALA B CB 1 ATOM 5068 N N . THR B 1 268 ? -3.643 -43.107 -43.945 1.00 52.24 ? 268 THR B N 1 ATOM 5069 C CA . THR B 1 268 ? -2.374 -43.775 -44.229 1.00 51.20 ? 268 THR B CA 1 ATOM 5070 C C . THR B 1 268 ? -1.282 -42.764 -44.491 1.00 57.59 ? 268 THR B C 1 ATOM 5071 O O . THR B 1 268 ? -1.176 -42.236 -45.595 1.00 57.23 ? 268 THR B O 1 ATOM 5072 C CB . THR B 1 268 ? -2.538 -44.746 -45.398 1.00 48.38 ? 268 THR B CB 1 ATOM 5073 O OG1 . THR B 1 268 ? -3.636 -45.625 -45.140 1.00 55.04 ? 268 THR B OG1 1 ATOM 5074 C CG2 . THR B 1 268 ? -1.296 -45.538 -45.680 1.00 35.67 ? 268 THR B CG2 1 ATOM 5075 N N . GLU B 1 269 ? -0.465 -42.495 -43.477 1.00 57.08 ? 269 GLU B N 1 ATOM 5076 C CA . GLU B 1 269 ? 0.643 -41.552 -43.580 1.00 58.07 ? 269 GLU B CA 1 ATOM 5077 C C . GLU B 1 269 ? 1.786 -42.126 -44.411 1.00 63.51 ? 269 GLU B C 1 ATOM 5078 O O . GLU B 1 269 ? 2.028 -43.328 -44.395 1.00 62.37 ? 269 GLU B O 1 ATOM 5079 C CB . GLU B 1 269 ? 1.127 -41.155 -42.181 1.00 59.98 ? 269 GLU B CB 1 ATOM 5080 C CG . GLU B 1 269 ? 1.791 -39.786 -42.131 1.00 80.04 ? 269 GLU B CG 1 ATOM 5081 C CD . GLU B 1 269 ? 2.172 -39.227 -40.765 1.00 109.45 ? 269 GLU B CD 1 ATOM 5082 O OE1 . GLU B 1 269 ? 2.150 -39.985 -39.764 1.00 98.48 ? 269 GLU B OE1 1 ATOM 5083 O OE2 . GLU B 1 269 ? 2.522 -38.023 -40.705 1.00 99.48 ? 269 GLU B OE2 1 ATOM 5084 N N . ILE B 1 270 ? 2.432 -41.276 -45.194 1.00 63.53 ? 270 ILE B N 1 ATOM 5085 C CA . ILE B 1 270 ? 3.600 -41.604 -46.022 1.00 65.02 ? 270 ILE B CA 1 ATOM 5086 C C . ILE B 1 270 ? 4.725 -40.683 -45.581 1.00 79.23 ? 270 ILE B C 1 ATOM 5087 O O . ILE B 1 270 ? 4.490 -39.501 -45.312 1.00 78.98 ? 270 ILE B O 1 ATOM 5088 C CB . ILE B 1 270 ? 3.319 -41.560 -47.565 1.00 65.61 ? 270 ILE B CB 1 ATOM 5089 C CG1 . ILE B 1 270 ? 3.024 -42.956 -48.126 1.00 63.72 ? 270 ILE B CG1 1 ATOM 5090 C CG2 . ILE B 1 270 ? 4.452 -40.894 -48.367 1.00 64.06 ? 270 ILE B CG2 1 ATOM 5091 C CD1 . ILE B 1 270 ? 1.715 -43.497 -47.827 1.00 64.07 ? 270 ILE B CD1 1 ATOM 5092 N N . GLN B 1 271 ? 5.922 -41.225 -45.440 1.00 83.96 ? 271 GLN B N 1 ATOM 5093 C CA . GLN B 1 271 ? 7.019 -40.374 -45.024 1.00 88.54 ? 271 GLN B CA 1 ATOM 5094 C C . GLN B 1 271 ? 7.779 -39.789 -46.219 1.00 103.15 ? 271 GLN B C 1 ATOM 5095 O O . GLN B 1 271 ? 7.725 -40.328 -47.336 1.00 103.24 ? 271 GLN B O 1 ATOM 5096 C CB . GLN B 1 271 ? 7.947 -41.109 -44.045 1.00 90.08 ? 271 GLN B CB 1 ATOM 5097 C CG . GLN B 1 271 ? 8.010 -40.456 -42.663 1.00 105.56 ? 271 GLN B CG 1 ATOM 5098 C CD . GLN B 1 271 ? 6.776 -40.680 -41.810 1.00 117.89 ? 271 GLN B CD 1 ATOM 5099 O OE1 . GLN B 1 271 ? 5.993 -41.626 -42.006 1.00 107.08 ? 271 GLN B OE1 1 ATOM 5100 N NE2 . GLN B 1 271 ? 6.598 -39.819 -40.818 1.00 109.96 ? 271 GLN B NE2 1 ATOM 5101 N N . MET B 1 272 ? 8.434 -38.643 -45.984 1.00 106.73 ? 272 MET B N 1 ATOM 5102 C CA . MET B 1 272 ? 9.292 -37.952 -46.941 1.00 110.15 ? 272 MET B CA 1 ATOM 5103 C C . MET B 1 272 ? 10.491 -37.499 -46.109 1.00 118.70 ? 272 MET B C 1 ATOM 5104 O O . MET B 1 272 ? 10.557 -36.344 -45.665 1.00 119.37 ? 272 MET B O 1 ATOM 5105 C CB . MET B 1 272 ? 8.567 -36.803 -47.694 1.00 113.50 ? 272 MET B CB 1 ATOM 5106 C CG . MET B 1 272 ? 7.459 -37.293 -48.644 1.00 118.80 ? 272 MET B CG 1 ATOM 5107 S SD . MET B 1 272 ? 7.016 -36.224 -50.056 1.00 124.69 ? 272 MET B SD 1 ATOM 5108 C CE . MET B 1 272 ? 6.058 -34.893 -49.216 1.00 121.37 ? 272 MET B CE 1 ATOM 5109 N N . SER B 1 273 ? 11.381 -38.479 -45.800 1.00 116.94 ? 273 SER B N 1 ATOM 5110 C CA . SER B 1 273 ? 12.581 -38.338 -44.954 1.00 117.18 ? 273 SER B CA 1 ATOM 5111 C C . SER B 1 273 ? 13.566 -37.294 -45.471 1.00 121.57 ? 273 SER B C 1 ATOM 5112 O O . SER B 1 273 ? 14.160 -36.557 -44.679 1.00 121.34 ? 273 SER B O 1 ATOM 5113 C CB . SER B 1 273 ? 13.267 -39.687 -44.762 1.00 120.50 ? 273 SER B CB 1 ATOM 5114 O OG . SER B 1 273 ? 13.674 -40.224 -46.009 1.00 129.46 ? 273 SER B OG 1 ATOM 5115 N N . SER B 1 274 ? 13.729 -37.245 -46.800 1.00 118.25 ? 274 SER B N 1 ATOM 5116 C CA . SER B 1 274 ? 14.562 -36.287 -47.518 1.00 118.44 ? 274 SER B CA 1 ATOM 5117 C C . SER B 1 274 ? 13.953 -36.109 -48.917 1.00 121.60 ? 274 SER B C 1 ATOM 5118 O O . SER B 1 274 ? 14.510 -36.543 -49.939 1.00 120.78 ? 274 SER B O 1 ATOM 5119 C CB . SER B 1 274 ? 16.032 -36.711 -47.540 1.00 123.43 ? 274 SER B CB 1 ATOM 5120 O OG . SER B 1 274 ? 16.207 -38.063 -47.932 1.00 136.95 ? 274 SER B OG 1 ATOM 5121 N N . GLY B 1 275 ? 12.747 -35.534 -48.905 1.00 117.16 ? 275 GLY B N 1 ATOM 5122 C CA . GLY B 1 275 ? 11.943 -35.236 -50.085 1.00 116.06 ? 275 GLY B CA 1 ATOM 5123 C C . GLY B 1 275 ? 11.531 -36.414 -50.943 1.00 117.15 ? 275 GLY B C 1 ATOM 5124 O O . GLY B 1 275 ? 11.200 -36.216 -52.114 1.00 116.32 ? 275 GLY B O 1 ATOM 5125 N N . ASN B 1 276 ? 11.541 -37.642 -50.389 1.00 112.22 ? 276 ASN B N 1 ATOM 5126 C CA . ASN B 1 276 ? 11.136 -38.797 -51.179 1.00 111.21 ? 276 ASN B CA 1 ATOM 5127 C C . ASN B 1 276 ? 10.090 -39.668 -50.491 1.00 112.76 ? 276 ASN B C 1 ATOM 5128 O O . ASN B 1 276 ? 9.953 -39.668 -49.271 1.00 111.89 ? 276 ASN B O 1 ATOM 5129 C CB . ASN B 1 276 ? 12.319 -39.629 -51.683 1.00 112.21 ? 276 ASN B CB 1 ATOM 5130 C CG . ASN B 1 276 ? 12.084 -40.178 -53.091 1.00 137.22 ? 276 ASN B CG 1 ATOM 5131 O OD1 . ASN B 1 276 ? 10.962 -40.145 -53.633 1.00 129.94 ? 276 ASN B OD1 1 ATOM 5132 N ND2 . ASN B 1 276 ? 13.132 -40.698 -53.724 1.00 127.54 ? 276 ASN B ND2 1 ATOM 5133 N N . LEU B 1 277 ? 9.347 -40.401 -51.323 1.00 107.96 ? 277 LEU B N 1 ATOM 5134 C CA . LEU B 1 277 ? 8.223 -41.264 -50.987 1.00 107.20 ? 277 LEU B CA 1 ATOM 5135 C C . LEU B 1 277 ? 8.672 -42.596 -50.324 1.00 110.50 ? 277 LEU B C 1 ATOM 5136 O O . LEU B 1 277 ? 9.030 -43.556 -51.009 1.00 109.77 ? 277 LEU B O 1 ATOM 5137 C CB . LEU B 1 277 ? 7.353 -41.466 -52.266 1.00 107.05 ? 277 LEU B CB 1 ATOM 5138 C CG . LEU B 1 277 ? 7.202 -40.225 -53.217 1.00 110.75 ? 277 LEU B CG 1 ATOM 5139 C CD1 . LEU B 1 277 ? 6.868 -40.630 -54.644 1.00 109.98 ? 277 LEU B CD1 1 ATOM 5140 C CD2 . LEU B 1 277 ? 6.215 -39.176 -52.661 1.00 112.32 ? 277 LEU B CD2 1 ATOM 5141 N N . LEU B 1 278 ? 8.660 -42.623 -48.970 1.00 106.94 ? 278 LEU B N 1 ATOM 5142 C CA . LEU B 1 278 ? 9.090 -43.752 -48.135 1.00 106.80 ? 278 LEU B CA 1 ATOM 5143 C C . LEU B 1 278 ? 7.893 -44.515 -47.560 1.00 113.43 ? 278 LEU B C 1 ATOM 5144 O O . LEU B 1 278 ? 7.462 -44.249 -46.431 1.00 113.32 ? 278 LEU B O 1 ATOM 5145 C CB . LEU B 1 278 ? 10.000 -43.226 -47.008 1.00 106.47 ? 278 LEU B CB 1 ATOM 5146 C CG . LEU B 1 278 ? 11.511 -43.301 -47.226 1.00 110.97 ? 278 LEU B CG 1 ATOM 5147 C CD1 . LEU B 1 278 ? 12.023 -42.207 -48.189 1.00 110.68 ? 278 LEU B CD1 1 ATOM 5148 C CD2 . LEU B 1 278 ? 12.234 -43.200 -45.900 1.00 113.97 ? 278 LEU B CD2 1 ATOM 5149 N N . PHE B 1 279 ? 7.364 -45.475 -48.337 1.00 112.01 ? 279 PHE B N 1 ATOM 5150 C CA . PHE B 1 279 ? 6.186 -46.272 -47.989 1.00 113.00 ? 279 PHE B CA 1 ATOM 5151 C C . PHE B 1 279 ? 6.429 -47.380 -46.946 1.00 119.94 ? 279 PHE B C 1 ATOM 5152 O O . PHE B 1 279 ? 7.532 -47.925 -46.873 1.00 119.95 ? 279 PHE B O 1 ATOM 5153 C CB . PHE B 1 279 ? 5.563 -46.850 -49.268 1.00 115.14 ? 279 PHE B CB 1 ATOM 5154 C CG . PHE B 1 279 ? 4.236 -47.551 -49.094 1.00 117.35 ? 279 PHE B CG 1 ATOM 5155 C CD1 . PHE B 1 279 ? 3.248 -47.018 -48.266 1.00 119.97 ? 279 PHE B CD1 1 ATOM 5156 C CD2 . PHE B 1 279 ? 3.967 -48.738 -49.761 1.00 121.09 ? 279 PHE B CD2 1 ATOM 5157 C CE1 . PHE B 1 279 ? 2.037 -47.685 -48.074 1.00 123.10 ? 279 PHE B CE1 1 ATOM 5158 C CE2 . PHE B 1 279 ? 2.744 -49.395 -49.586 1.00 122.42 ? 279 PHE B CE2 1 ATOM 5159 C CZ . PHE B 1 279 ? 1.789 -48.863 -48.744 1.00 121.61 ? 279 PHE B CZ 1 ATOM 5160 N N . THR B 1 280 ? 5.366 -47.713 -46.149 1.00 118.80 ? 280 THR B N 1 ATOM 5161 C CA . THR B 1 280 ? 5.329 -48.753 -45.089 1.00 119.25 ? 280 THR B CA 1 ATOM 5162 C C . THR B 1 280 ? 5.264 -50.183 -45.677 1.00 122.48 ? 280 THR B C 1 ATOM 5163 O O . THR B 1 280 ? 5.518 -51.149 -44.955 1.00 121.88 ? 280 THR B O 1 ATOM 5164 C CB . THR B 1 280 ? 4.205 -48.477 -44.038 1.00 129.12 ? 280 THR B CB 1 ATOM 5165 O OG1 . THR B 1 280 ? 4.620 -48.952 -42.755 1.00 129.45 ? 280 THR B OG1 1 ATOM 5166 C CG2 . THR B 1 280 ? 2.849 -49.093 -44.409 1.00 127.49 ? 280 THR B CG2 1 ATOM 5167 N N . GLY B 1 281 ? 4.921 -50.286 -46.963 1.00 118.67 ? 281 GLY B N 1 ATOM 5168 C CA . GLY B 1 281 ? 4.857 -51.544 -47.698 1.00 118.27 ? 281 GLY B CA 1 ATOM 5169 C C . GLY B 1 281 ? 6.229 -52.139 -47.953 1.00 121.09 ? 281 GLY B C 1 ATOM 5170 O O . GLY B 1 281 ? 7.258 -51.461 -47.802 1.00 120.67 ? 281 GLY B O 1 ATOM 5171 N N . HIS B 1 282 ? 6.248 -53.421 -48.336 1.00 116.05 ? 282 HIS B N 1 ATOM 5172 C CA . HIS B 1 282 ? 7.487 -54.152 -48.568 1.00 115.22 ? 282 HIS B CA 1 ATOM 5173 C C . HIS B 1 282 ? 7.525 -54.882 -49.913 1.00 114.12 ? 282 HIS B C 1 ATOM 5174 O O . HIS B 1 282 ? 6.485 -55.088 -50.547 1.00 114.13 ? 282 HIS B O 1 ATOM 5175 C CB . HIS B 1 282 ? 7.770 -55.107 -47.394 1.00 116.93 ? 282 HIS B CB 1 ATOM 5176 C CG . HIS B 1 282 ? 6.651 -56.063 -47.103 1.00 121.13 ? 282 HIS B CG 1 ATOM 5177 N ND1 . HIS B 1 282 ? 5.616 -55.721 -46.250 1.00 123.23 ? 282 HIS B ND1 1 ATOM 5178 C CD2 . HIS B 1 282 ? 6.434 -57.315 -47.575 1.00 123.29 ? 282 HIS B CD2 1 ATOM 5179 C CE1 . HIS B 1 282 ? 4.810 -56.773 -46.225 1.00 122.80 ? 282 HIS B CE1 1 ATOM 5180 N NE2 . HIS B 1 282 ? 5.267 -57.761 -46.999 1.00 123.12 ? 282 HIS B NE2 1 ATOM 5181 N N . LEU B 1 283 ? 8.741 -55.269 -50.341 1.00 106.01 ? 283 LEU B N 1 ATOM 5182 C CA . LEU B 1 283 ? 8.995 -55.954 -51.603 1.00 103.24 ? 283 LEU B CA 1 ATOM 5183 C C . LEU B 1 283 ? 9.424 -57.402 -51.363 1.00 104.79 ? 283 LEU B C 1 ATOM 5184 O O . LEU B 1 283 ? 10.514 -57.642 -50.832 1.00 103.95 ? 283 LEU B O 1 ATOM 5185 C CB . LEU B 1 283 ? 10.078 -55.179 -52.359 1.00 102.32 ? 283 LEU B CB 1 ATOM 5186 C CG . LEU B 1 283 ? 10.140 -55.354 -53.854 1.00 105.39 ? 283 LEU B CG 1 ATOM 5187 C CD1 . LEU B 1 283 ? 8.796 -55.050 -54.516 1.00 105.40 ? 283 LEU B CD1 1 ATOM 5188 C CD2 . LEU B 1 283 ? 11.182 -54.459 -54.412 1.00 105.66 ? 283 LEU B CD2 1 ATOM 5189 N N . LYS B 1 284 ? 8.550 -58.364 -51.728 1.00 99.78 ? 284 LYS B N 1 ATOM 5190 C CA . LYS B 1 284 ? 8.817 -59.797 -51.560 1.00 98.68 ? 284 LYS B CA 1 ATOM 5191 C C . LYS B 1 284 ? 9.500 -60.356 -52.792 1.00 102.58 ? 284 LYS B C 1 ATOM 5192 O O . LYS B 1 284 ? 8.885 -60.509 -53.850 1.00 102.12 ? 284 LYS B O 1 ATOM 5193 C CB . LYS B 1 284 ? 7.555 -60.598 -51.176 1.00 99.92 ? 284 LYS B CB 1 ATOM 5194 C CG . LYS B 1 284 ? 7.160 -60.467 -49.701 1.00 101.58 ? 284 LYS B CG 1 ATOM 5195 C CD . LYS B 1 284 ? 5.926 -61.318 -49.344 1.00 98.91 ? 284 LYS B CD 1 ATOM 5196 C CE . LYS B 1 284 ? 5.568 -61.243 -47.875 1.00 87.51 ? 284 LYS B CE 1 ATOM 5197 N NZ . LYS B 1 284 ? 4.484 -62.192 -47.531 1.00 82.53 ? 284 LYS B NZ 1 ATOM 5198 N N . CYS B 1 285 ? 10.797 -60.625 -52.655 1.00 99.81 ? 285 CYS B N 1 ATOM 5199 C CA . CYS B 1 285 ? 11.607 -61.127 -53.752 1.00 100.19 ? 285 CYS B CA 1 ATOM 5200 C C . CYS B 1 285 ? 12.017 -62.567 -53.603 1.00 102.54 ? 285 CYS B C 1 ATOM 5201 O O . CYS B 1 285 ? 12.022 -63.135 -52.504 1.00 102.93 ? 285 CYS B O 1 ATOM 5202 C CB . CYS B 1 285 ? 12.822 -60.236 -53.980 1.00 101.16 ? 285 CYS B CB 1 ATOM 5203 S SG . CYS B 1 285 ? 12.415 -58.492 -54.189 1.00 105.60 ? 285 CYS B SG 1 ATOM 5204 N N . ARG B 1 286 ? 12.384 -63.136 -54.742 1.00 96.29 ? 286 ARG B N 1 ATOM 5205 C CA . ARG B 1 286 ? 12.927 -64.458 -54.887 1.00 95.13 ? 286 ARG B CA 1 ATOM 5206 C C . ARG B 1 286 ? 14.287 -64.242 -55.518 1.00 99.99 ? 286 ARG B C 1 ATOM 5207 O O . ARG B 1 286 ? 14.443 -63.360 -56.369 1.00 99.87 ? 286 ARG B O 1 ATOM 5208 C CB . ARG B 1 286 ? 12.022 -65.330 -55.741 1.00 92.32 ? 286 ARG B CB 1 ATOM 5209 C CG . ARG B 1 286 ? 12.186 -66.786 -55.392 1.00 102.24 ? 286 ARG B CG 1 ATOM 5210 C CD . ARG B 1 286 ? 11.008 -67.614 -55.850 1.00 113.54 ? 286 ARG B CD 1 ATOM 5211 N NE . ARG B 1 286 ? 10.341 -68.287 -54.736 1.00 120.72 ? 286 ARG B NE 1 ATOM 5212 C CZ . ARG B 1 286 ? 10.712 -69.460 -54.229 1.00 137.63 ? 286 ARG B CZ 1 ATOM 5213 N NH1 . ARG B 1 286 ? 11.769 -70.097 -54.716 1.00 121.97 ? 286 ARG B NH1 1 ATOM 5214 N NH2 . ARG B 1 286 ? 10.043 -69.994 -53.219 1.00 130.98 ? 286 ARG B NH2 1 ATOM 5215 N N . LEU B 1 287 ? 15.280 -65.004 -55.060 1.00 96.61 ? 287 LEU B N 1 ATOM 5216 C CA . LEU B 1 287 ? 16.642 -64.819 -55.512 1.00 96.21 ? 287 LEU B CA 1 ATOM 5217 C C . LEU B 1 287 ? 17.303 -66.101 -55.977 1.00 101.20 ? 287 LEU B C 1 ATOM 5218 O O . LEU B 1 287 ? 17.430 -67.041 -55.198 1.00 100.35 ? 287 LEU B O 1 ATOM 5219 C CB . LEU B 1 287 ? 17.437 -64.188 -54.368 1.00 95.92 ? 287 LEU B CB 1 ATOM 5220 C CG . LEU B 1 287 ? 18.518 -63.235 -54.757 1.00 100.01 ? 287 LEU B CG 1 ATOM 5221 C CD1 . LEU B 1 287 ? 18.061 -61.818 -54.566 1.00 99.75 ? 287 LEU B CD1 1 ATOM 5222 C CD2 . LEU B 1 287 ? 19.748 -63.490 -53.939 1.00 103.12 ? 287 LEU B CD2 1 ATOM 5223 N N . ARG B 1 288 ? 17.727 -66.127 -57.254 1.00 99.34 ? 288 ARG B N 1 ATOM 5224 C CA . ARG B 1 288 ? 18.462 -67.231 -57.861 1.00 99.46 ? 288 ARG B CA 1 ATOM 5225 C C . ARG B 1 288 ? 19.911 -66.822 -57.973 1.00 105.63 ? 288 ARG B C 1 ATOM 5226 O O . ARG B 1 288 ? 20.233 -65.719 -58.439 1.00 105.44 ? 288 ARG B O 1 ATOM 5227 C CB . ARG B 1 288 ? 17.848 -67.700 -59.180 1.00 98.31 ? 288 ARG B CB 1 ATOM 5228 C CG . ARG B 1 288 ? 16.786 -68.763 -58.923 1.00 110.03 ? 288 ARG B CG 1 ATOM 5229 C CD . ARG B 1 288 ? 16.120 -69.309 -60.175 1.00 125.49 ? 288 ARG B CD 1 ATOM 5230 N NE . ARG B 1 288 ? 16.877 -70.385 -60.832 1.00 134.79 ? 288 ARG B NE 1 ATOM 5231 C CZ . ARG B 1 288 ? 16.841 -71.671 -60.482 1.00 143.48 ? 288 ARG B CZ 1 ATOM 5232 N NH1 . ARG B 1 288 ? 16.130 -72.061 -59.429 1.00 129.38 ? 288 ARG B NH1 1 ATOM 5233 N NH2 . ARG B 1 288 ? 17.541 -72.570 -61.162 1.00 123.56 ? 288 ARG B NH2 1 ATOM 5234 N N . MET B 1 289 ? 20.771 -67.691 -57.442 1.00 103.65 ? 289 MET B N 1 ATOM 5235 C CA . MET B 1 289 ? 22.211 -67.516 -57.292 1.00 104.14 ? 289 MET B CA 1 ATOM 5236 C C . MET B 1 289 ? 23.028 -68.542 -58.073 1.00 109.57 ? 289 MET B C 1 ATOM 5237 O O . MET B 1 289 ? 24.246 -68.600 -57.919 1.00 108.78 ? 289 MET B O 1 ATOM 5238 C CB . MET B 1 289 ? 22.537 -67.571 -55.799 1.00 106.43 ? 289 MET B CB 1 ATOM 5239 C CG . MET B 1 289 ? 22.072 -66.346 -55.057 1.00 109.88 ? 289 MET B CG 1 ATOM 5240 S SD . MET B 1 289 ? 22.070 -66.575 -53.275 1.00 113.67 ? 289 MET B SD 1 ATOM 5241 C CE . MET B 1 289 ? 23.009 -65.154 -52.735 1.00 109.92 ? 289 MET B CE 1 ATOM 5242 N N . ASP B 1 290 ? 22.359 -69.323 -58.947 1.00 107.45 ? 290 ASP B N 1 ATOM 5243 C CA . ASP B 1 290 ? 22.982 -70.335 -59.806 1.00 107.52 ? 290 ASP B CA 1 ATOM 5244 C C . ASP B 1 290 ? 24.066 -69.711 -60.693 1.00 110.56 ? 290 ASP B C 1 ATOM 5245 O O . ASP B 1 290 ? 25.121 -70.317 -60.881 1.00 110.59 ? 290 ASP B O 1 ATOM 5246 C CB . ASP B 1 290 ? 21.919 -71.054 -60.662 1.00 110.01 ? 290 ASP B CB 1 ATOM 5247 C CG . ASP B 1 290 ? 21.087 -70.140 -61.550 1.00 128.91 ? 290 ASP B CG 1 ATOM 5248 O OD1 . ASP B 1 290 ? 20.106 -69.541 -61.038 1.00 131.55 ? 290 ASP B OD1 1 ATOM 5249 O OD2 . ASP B 1 290 ? 21.405 -70.037 -62.761 1.00 136.42 ? 290 ASP B OD2 1 ATOM 5250 N N . LYS B 1 291 ? 23.820 -68.474 -61.188 1.00 105.61 ? 291 LYS B N 1 ATOM 5251 C CA . LYS B 1 291 ? 24.743 -67.740 -62.055 1.00 104.14 ? 291 LYS B CA 1 ATOM 5252 C C . LYS B 1 291 ? 25.777 -66.890 -61.282 1.00 104.70 ? 291 LYS B C 1 ATOM 5253 O O . LYS B 1 291 ? 26.632 -66.249 -61.894 1.00 103.35 ? 291 LYS B O 1 ATOM 5254 C CB . LYS B 1 291 ? 23.959 -66.912 -63.084 1.00 106.43 ? 291 LYS B CB 1 ATOM 5255 C CG . LYS B 1 291 ? 23.628 -67.699 -64.363 1.00 114.26 ? 291 LYS B CG 1 ATOM 5256 C CD . LYS B 1 291 ? 22.804 -66.893 -65.347 1.00 121.16 ? 291 LYS B CD 1 ATOM 5257 C CE . LYS B 1 291 ? 23.352 -66.953 -66.754 1.00 125.98 ? 291 LYS B CE 1 ATOM 5258 N NZ . LYS B 1 291 ? 22.976 -65.739 -67.524 1.00 129.57 ? 291 LYS B NZ 1 ATOM 5259 N N . LEU B 1 292 ? 25.710 -66.912 -59.945 1.00 100.27 ? 292 LEU B N 1 ATOM 5260 C CA . LEU B 1 292 ? 26.661 -66.223 -59.079 1.00 99.38 ? 292 LEU B CA 1 ATOM 5261 C C . LEU B 1 292 ? 27.824 -67.156 -58.779 1.00 100.15 ? 292 LEU B C 1 ATOM 5262 O O . LEU B 1 292 ? 27.625 -68.359 -58.591 1.00 100.21 ? 292 LEU B O 1 ATOM 5263 C CB . LEU B 1 292 ? 26.013 -65.832 -57.748 1.00 99.62 ? 292 LEU B CB 1 ATOM 5264 C CG . LEU B 1 292 ? 25.412 -64.456 -57.605 1.00 104.18 ? 292 LEU B CG 1 ATOM 5265 C CD1 . LEU B 1 292 ? 24.962 -64.244 -56.187 1.00 104.42 ? 292 LEU B CD1 1 ATOM 5266 C CD2 . LEU B 1 292 ? 26.390 -63.353 -58.005 1.00 105.20 ? 292 LEU B CD2 1 ATOM 5267 N N . GLN B 1 293 ? 29.022 -66.586 -58.670 1.00 93.16 ? 293 GLN B N 1 ATOM 5268 C CA . GLN B 1 293 ? 30.239 -67.314 -58.377 1.00 91.38 ? 293 GLN B CA 1 ATOM 5269 C C . GLN B 1 293 ? 31.164 -66.502 -57.479 1.00 93.22 ? 293 GLN B C 1 ATOM 5270 O O . GLN B 1 293 ? 31.186 -65.266 -57.548 1.00 91.89 ? 293 GLN B O 1 ATOM 5271 C CB . GLN B 1 293 ? 30.939 -67.747 -59.680 1.00 92.87 ? 293 GLN B CB 1 ATOM 5272 C CG . GLN B 1 293 ? 31.168 -66.611 -60.680 1.00 121.14 ? 293 GLN B CG 1 ATOM 5273 C CD . GLN B 1 293 ? 31.622 -67.102 -62.030 1.00 147.25 ? 293 GLN B CD 1 ATOM 5274 O OE1 . GLN B 1 293 ? 32.766 -66.863 -62.440 1.00 143.49 ? 293 GLN B OE1 1 ATOM 5275 N NE2 . GLN B 1 293 ? 30.726 -67.765 -62.766 1.00 139.93 ? 293 GLN B NE2 1 ATOM 5276 N N . LEU B 1 294 ? 31.938 -67.211 -56.641 1.00 90.27 ? 294 LEU B N 1 ATOM 5277 C CA . LEU B 1 294 ? 32.913 -66.637 -55.712 1.00 90.57 ? 294 LEU B CA 1 ATOM 5278 C C . LEU B 1 294 ? 34.090 -66.038 -56.465 1.00 98.77 ? 294 LEU B C 1 ATOM 5279 O O . LEU B 1 294 ? 34.662 -66.721 -57.314 1.00 98.99 ? 294 LEU B O 1 ATOM 5280 C CB . LEU B 1 294 ? 33.406 -67.731 -54.787 1.00 90.02 ? 294 LEU B CB 1 ATOM 5281 C CG . LEU B 1 294 ? 32.536 -68.036 -53.610 1.00 94.42 ? 294 LEU B CG 1 ATOM 5282 C CD1 . LEU B 1 294 ? 32.990 -69.294 -52.959 1.00 95.06 ? 294 LEU B CD1 1 ATOM 5283 C CD2 . LEU B 1 294 ? 32.583 -66.906 -52.620 1.00 97.47 ? 294 LEU B CD2 1 ATOM 5284 N N . LYS B 1 295 ? 34.470 -64.790 -56.153 1.00 97.90 ? 295 LYS B N 1 ATOM 5285 C CA . LYS B 1 295 ? 35.543 -64.136 -56.896 1.00 99.36 ? 295 LYS B CA 1 ATOM 5286 C C . LYS B 1 295 ? 36.856 -64.922 -56.943 1.00 109.11 ? 295 LYS B C 1 ATOM 5287 O O . LYS B 1 295 ? 37.229 -65.294 -58.051 1.00 109.22 ? 295 LYS B O 1 ATOM 5288 C CB . LYS B 1 295 ? 35.772 -62.675 -56.479 1.00 101.28 ? 295 LYS B CB 1 ATOM 5289 C CG . LYS B 1 295 ? 36.592 -61.870 -57.501 1.00 106.98 ? 295 LYS B CG 1 ATOM 5290 C CD . LYS B 1 295 ? 37.145 -60.559 -56.944 1.00 111.33 ? 295 LYS B CD 1 ATOM 5291 C CE . LYS B 1 295 ? 37.612 -59.580 -58.009 1.00 116.87 ? 295 LYS B CE 1 ATOM 5292 N NZ . LYS B 1 295 ? 38.738 -60.113 -58.816 1.00 122.79 ? 295 LYS B NZ 1 ATOM 5293 N N . GLY B 1 296 ? 37.554 -65.140 -55.837 1.00 109.96 ? 296 GLY B N 1 ATOM 5294 C CA . GLY B 1 296 ? 38.842 -65.829 -55.912 1.00 111.85 ? 296 GLY B CA 1 ATOM 5295 C C . GLY B 1 296 ? 38.900 -67.294 -55.518 1.00 120.10 ? 296 GLY B C 1 ATOM 5296 O O . GLY B 1 296 ? 39.864 -67.692 -54.858 1.00 119.80 ? 296 GLY B O 1 ATOM 5297 N N . MET B 1 297 ? 37.913 -68.127 -55.954 1.00 119.40 ? 297 MET B N 1 ATOM 5298 C CA . MET B 1 297 ? 37.848 -69.565 -55.609 1.00 120.11 ? 297 MET B CA 1 ATOM 5299 C C . MET B 1 297 ? 39.000 -70.371 -56.253 1.00 122.77 ? 297 MET B C 1 ATOM 5300 O O . MET B 1 297 ? 39.305 -71.483 -55.800 1.00 122.78 ? 297 MET B O 1 ATOM 5301 C CB . MET B 1 297 ? 36.455 -70.190 -55.902 1.00 122.94 ? 297 MET B CB 1 ATOM 5302 C CG . MET B 1 297 ? 36.086 -71.374 -54.983 1.00 127.47 ? 297 MET B CG 1 ATOM 5303 S SD . MET B 1 297 ? 36.543 -71.209 -53.220 1.00 132.68 ? 297 MET B SD 1 ATOM 5304 C CE . MET B 1 297 ? 36.064 -72.842 -52.600 1.00 129.69 ? 297 MET B CE 1 ATOM 5305 N N . SER B 1 298 ? 39.672 -69.770 -57.257 1.00 117.08 ? 298 SER B N 1 ATOM 5306 C CA . SER B 1 298 ? 40.794 -70.358 -57.984 1.00 115.87 ? 298 SER B CA 1 ATOM 5307 C C . SER B 1 298 ? 42.143 -69.759 -57.570 1.00 117.84 ? 298 SER B C 1 ATOM 5308 O O . SER B 1 298 ? 43.190 -70.303 -57.938 1.00 117.43 ? 298 SER B O 1 ATOM 5309 C CB . SER B 1 298 ? 40.572 -70.258 -59.493 1.00 118.83 ? 298 SER B CB 1 ATOM 5310 O OG . SER B 1 298 ? 40.256 -68.942 -59.926 1.00 125.42 ? 298 SER B OG 1 ATOM 5311 N N . TYR B 1 299 ? 42.127 -68.662 -56.783 1.00 113.23 ? 299 TYR B N 1 ATOM 5312 C CA . TYR B 1 299 ? 43.367 -68.036 -56.312 1.00 112.59 ? 299 TYR B CA 1 ATOM 5313 C C . TYR B 1 299 ? 44.026 -68.935 -55.274 1.00 113.39 ? 299 TYR B C 1 ATOM 5314 O O . TYR B 1 299 ? 43.352 -69.699 -54.580 1.00 112.29 ? 299 TYR B O 1 ATOM 5315 C CB . TYR B 1 299 ? 43.138 -66.652 -55.663 1.00 114.57 ? 299 TYR B CB 1 ATOM 5316 C CG . TYR B 1 299 ? 42.562 -65.531 -56.513 1.00 117.38 ? 299 TYR B CG 1 ATOM 5317 C CD1 . TYR B 1 299 ? 42.448 -65.654 -57.897 1.00 119.10 ? 299 TYR B CD1 1 ATOM 5318 C CD2 . TYR B 1 299 ? 42.174 -64.328 -55.936 1.00 119.07 ? 299 TYR B CD2 1 ATOM 5319 C CE1 . TYR B 1 299 ? 41.929 -64.619 -58.679 1.00 119.96 ? 299 TYR B CE1 1 ATOM 5320 C CE2 . TYR B 1 299 ? 41.637 -63.293 -56.703 1.00 120.55 ? 299 TYR B CE2 1 ATOM 5321 C CZ . TYR B 1 299 ? 41.508 -63.442 -58.073 1.00 129.01 ? 299 TYR B CZ 1 ATOM 5322 O OH . TYR B 1 299 ? 40.953 -62.408 -58.798 1.00 131.80 ? 299 TYR B OH 1 ATOM 5323 N N . SER B 1 300 ? 45.335 -68.821 -55.158 1.00 108.50 ? 300 SER B N 1 ATOM 5324 C CA . SER B 1 300 ? 46.135 -69.586 -54.209 1.00 107.69 ? 300 SER B CA 1 ATOM 5325 C C . SER B 1 300 ? 46.028 -68.977 -52.801 1.00 109.86 ? 300 SER B C 1 ATOM 5326 O O . SER B 1 300 ? 45.598 -67.832 -52.680 1.00 109.71 ? 300 SER B O 1 ATOM 5327 C CB . SER B 1 300 ? 47.586 -69.605 -54.677 1.00 111.26 ? 300 SER B CB 1 ATOM 5328 O OG . SER B 1 300 ? 48.047 -68.294 -54.976 1.00 120.71 ? 300 SER B OG 1 ATOM 5329 N N . MET B 1 301 ? 46.398 -69.737 -51.748 1.00 104.87 ? 301 MET B N 1 ATOM 5330 C CA . MET B 1 301 ? 46.356 -69.269 -50.361 1.00 104.34 ? 301 MET B CA 1 ATOM 5331 C C . MET B 1 301 ? 47.495 -68.320 -50.057 1.00 107.70 ? 301 MET B C 1 ATOM 5332 O O . MET B 1 301 ? 48.633 -68.594 -50.443 1.00 107.77 ? 301 MET B O 1 ATOM 5333 C CB . MET B 1 301 ? 46.415 -70.451 -49.394 1.00 106.96 ? 301 MET B CB 1 ATOM 5334 C CG . MET B 1 301 ? 45.207 -71.355 -49.466 1.00 111.25 ? 301 MET B CG 1 ATOM 5335 S SD . MET B 1 301 ? 43.740 -70.546 -48.788 1.00 116.42 ? 301 MET B SD 1 ATOM 5336 C CE . MET B 1 301 ? 44.013 -70.779 -47.032 1.00 113.14 ? 301 MET B CE 1 ATOM 5337 N N . CYS B 1 302 ? 47.203 -67.210 -49.355 1.00 104.06 ? 302 CYS B N 1 ATOM 5338 C CA . CYS B 1 302 ? 48.236 -66.244 -48.958 1.00 103.85 ? 302 CYS B CA 1 ATOM 5339 C C . CYS B 1 302 ? 49.216 -66.995 -48.050 1.00 106.20 ? 302 CYS B C 1 ATOM 5340 O O . CYS B 1 302 ? 48.799 -67.878 -47.293 1.00 105.40 ? 302 CYS B O 1 ATOM 5341 C CB . CYS B 1 302 ? 47.635 -65.036 -48.233 1.00 104.27 ? 302 CYS B CB 1 ATOM 5342 S SG . CYS B 1 302 ? 46.548 -63.989 -49.242 1.00 108.22 ? 302 CYS B SG 1 ATOM 5343 N N . THR B 1 303 ? 50.510 -66.678 -48.157 1.00 101.71 ? 303 THR B N 1 ATOM 5344 C CA . THR B 1 303 ? 51.533 -67.337 -47.334 1.00 101.19 ? 303 THR B CA 1 ATOM 5345 C C . THR B 1 303 ? 52.144 -66.373 -46.303 1.00 103.60 ? 303 THR B C 1 ATOM 5346 O O . THR B 1 303 ? 52.616 -66.805 -45.245 1.00 102.88 ? 303 THR B O 1 ATOM 5347 C CB . THR B 1 303 ? 52.606 -68.052 -48.203 1.00 108.71 ? 303 THR B CB 1 ATOM 5348 O OG1 . THR B 1 303 ? 53.281 -67.113 -49.045 1.00 108.99 ? 303 THR B OG1 1 ATOM 5349 C CG2 . THR B 1 303 ? 52.039 -69.210 -49.027 1.00 105.55 ? 303 THR B CG2 1 ATOM 5350 N N . GLY B 1 304 ? 52.098 -65.081 -46.623 1.00 98.58 ? 304 GLY B N 1 ATOM 5351 C CA . GLY B 1 304 ? 52.667 -64.017 -45.808 1.00 97.33 ? 304 GLY B CA 1 ATOM 5352 C C . GLY B 1 304 ? 52.039 -63.765 -44.457 1.00 98.14 ? 304 GLY B C 1 ATOM 5353 O O . GLY B 1 304 ? 51.226 -64.551 -43.958 1.00 96.71 ? 304 GLY B O 1 ATOM 5354 N N . LYS B 1 305 ? 52.457 -62.645 -43.862 1.00 93.58 ? 305 LYS B N 1 ATOM 5355 C CA . LYS B 1 305 ? 52.019 -62.177 -42.552 1.00 92.52 ? 305 LYS B CA 1 ATOM 5356 C C . LYS B 1 305 ? 51.008 -61.033 -42.704 1.00 93.96 ? 305 LYS B C 1 ATOM 5357 O O . LYS B 1 305 ? 51.040 -60.294 -43.695 1.00 92.48 ? 305 LYS B O 1 ATOM 5358 C CB . LYS B 1 305 ? 53.221 -61.746 -41.683 1.00 94.37 ? 305 LYS B CB 1 ATOM 5359 C CG . LYS B 1 305 ? 54.204 -62.854 -41.363 1.00 105.70 ? 305 LYS B CG 1 ATOM 5360 C CD . LYS B 1 305 ? 55.238 -62.406 -40.333 1.00 116.65 ? 305 LYS B CD 1 ATOM 5361 C CE . LYS B 1 305 ? 56.312 -63.447 -40.108 1.00 133.89 ? 305 LYS B CE 1 ATOM 5362 N NZ . LYS B 1 305 ? 56.523 -63.741 -38.664 1.00 146.12 ? 305 LYS B NZ 1 ATOM 5363 N N . PHE B 1 306 ? 50.115 -60.902 -41.713 1.00 89.08 ? 306 PHE B N 1 ATOM 5364 C CA . PHE B 1 306 ? 49.062 -59.900 -41.695 1.00 87.91 ? 306 PHE B CA 1 ATOM 5365 C C . PHE B 1 306 ? 49.164 -58.965 -40.508 1.00 91.80 ? 306 PHE B C 1 ATOM 5366 O O . PHE B 1 306 ? 49.523 -59.390 -39.416 1.00 91.08 ? 306 PHE B O 1 ATOM 5367 C CB . PHE B 1 306 ? 47.697 -60.588 -41.701 1.00 89.01 ? 306 PHE B CB 1 ATOM 5368 C CG . PHE B 1 306 ? 47.382 -61.339 -42.970 1.00 89.62 ? 306 PHE B CG 1 ATOM 5369 C CD1 . PHE B 1 306 ? 46.839 -60.685 -44.068 1.00 90.59 ? 306 PHE B CD1 1 ATOM 5370 C CD2 . PHE B 1 306 ? 47.615 -62.701 -43.065 1.00 92.60 ? 306 PHE B CD2 1 ATOM 5371 C CE1 . PHE B 1 306 ? 46.511 -61.384 -45.228 1.00 93.23 ? 306 PHE B CE1 1 ATOM 5372 C CE2 . PHE B 1 306 ? 47.305 -63.396 -44.235 1.00 93.66 ? 306 PHE B CE2 1 ATOM 5373 C CZ . PHE B 1 306 ? 46.768 -62.731 -45.313 1.00 91.83 ? 306 PHE B CZ 1 ATOM 5374 N N . LYS B 1 307 ? 48.821 -57.695 -40.721 1.00 89.43 ? 307 LYS B N 1 ATOM 5375 C CA . LYS B 1 307 ? 48.820 -56.647 -39.698 1.00 89.59 ? 307 LYS B CA 1 ATOM 5376 C C . LYS B 1 307 ? 47.365 -56.261 -39.360 1.00 95.09 ? 307 LYS B C 1 ATOM 5377 O O . LYS B 1 307 ? 46.484 -56.384 -40.210 1.00 94.05 ? 307 LYS B O 1 ATOM 5378 C CB . LYS B 1 307 ? 49.620 -55.429 -40.179 1.00 91.19 ? 307 LYS B CB 1 ATOM 5379 C CG . LYS B 1 307 ? 50.246 -54.640 -39.042 1.00 98.00 ? 307 LYS B CG 1 ATOM 5380 C CD . LYS B 1 307 ? 51.569 -55.303 -38.563 1.00 108.77 ? 307 LYS B CD 1 ATOM 5381 C CE . LYS B 1 307 ? 52.786 -54.435 -38.752 1.00 118.78 ? 307 LYS B CE 1 ATOM 5382 N NZ . LYS B 1 307 ? 53.961 -54.942 -37.982 1.00 127.56 ? 307 LYS B NZ 1 ATOM 5383 N N . ILE B 1 308 ? 47.128 -55.779 -38.130 1.00 93.00 ? 308 ILE B N 1 ATOM 5384 C CA . ILE B 1 308 ? 45.798 -55.418 -37.622 1.00 92.78 ? 308 ILE B CA 1 ATOM 5385 C C . ILE B 1 308 ? 45.524 -53.906 -37.686 1.00 95.58 ? 308 ILE B C 1 ATOM 5386 O O . ILE B 1 308 ? 45.805 -53.166 -36.744 1.00 95.17 ? 308 ILE B O 1 ATOM 5387 C CB . ILE B 1 308 ? 45.536 -56.012 -36.208 1.00 95.92 ? 308 ILE B CB 1 ATOM 5388 C CG1 . ILE B 1 308 ? 46.862 -56.462 -35.461 1.00 96.17 ? 308 ILE B CG1 1 ATOM 5389 C CG2 . ILE B 1 308 ? 44.570 -57.186 -36.343 1.00 96.46 ? 308 ILE B CG2 1 ATOM 5390 C CD1 . ILE B 1 308 ? 47.941 -55.343 -34.953 1.00 95.22 ? 308 ILE B CD1 1 ATOM 5391 N N . VAL B 1 309 ? 44.940 -53.475 -38.816 1.00 91.55 ? 309 VAL B N 1 ATOM 5392 C CA . VAL B 1 309 ? 44.561 -52.096 -39.177 1.00 90.61 ? 309 VAL B CA 1 ATOM 5393 C C . VAL B 1 309 ? 43.458 -51.550 -38.226 1.00 91.40 ? 309 VAL B C 1 ATOM 5394 O O . VAL B 1 309 ? 43.583 -50.453 -37.675 1.00 90.36 ? 309 VAL B O 1 ATOM 5395 C CB . VAL B 1 309 ? 44.106 -52.075 -40.671 1.00 95.04 ? 309 VAL B CB 1 ATOM 5396 C CG1 . VAL B 1 309 ? 43.635 -50.692 -41.115 1.00 95.30 ? 309 VAL B CG1 1 ATOM 5397 C CG2 . VAL B 1 309 ? 45.193 -52.606 -41.597 1.00 94.85 ? 309 VAL B CG2 1 ATOM 5398 N N . LYS B 1 310 ? 42.371 -52.315 -38.074 1.00 85.78 ? 310 LYS B N 1 ATOM 5399 C CA . LYS B 1 310 ? 41.248 -51.964 -37.224 1.00 83.84 ? 310 LYS B CA 1 ATOM 5400 C C . LYS B 1 310 ? 40.941 -53.142 -36.307 1.00 83.71 ? 310 LYS B C 1 ATOM 5401 O O . LYS B 1 310 ? 40.680 -54.267 -36.773 1.00 82.49 ? 310 LYS B O 1 ATOM 5402 C CB . LYS B 1 310 ? 40.018 -51.560 -38.063 1.00 85.96 ? 310 LYS B CB 1 ATOM 5403 C CG . LYS B 1 310 ? 39.127 -50.529 -37.399 1.00 94.33 ? 310 LYS B CG 1 ATOM 5404 C CD . LYS B 1 310 ? 38.246 -49.796 -38.392 1.00 90.86 ? 310 LYS B CD 1 ATOM 5405 C CE . LYS B 1 310 ? 37.448 -48.732 -37.685 1.00 87.14 ? 310 LYS B CE 1 ATOM 5406 N NZ . LYS B 1 310 ? 38.253 -47.504 -37.515 1.00 94.36 ? 310 LYS B NZ 1 ATOM 5407 N N . GLU B 1 311 ? 41.014 -52.866 -34.995 1.00 77.25 ? 311 GLU B N 1 ATOM 5408 C CA . GLU B 1 311 ? 40.757 -53.783 -33.900 1.00 75.96 ? 311 GLU B CA 1 ATOM 5409 C C . GLU B 1 311 ? 39.403 -54.493 -34.056 1.00 76.09 ? 311 GLU B C 1 ATOM 5410 O O . GLU B 1 311 ? 38.477 -53.928 -34.637 1.00 74.44 ? 311 GLU B O 1 ATOM 5411 C CB . GLU B 1 311 ? 40.800 -52.988 -32.586 1.00 77.79 ? 311 GLU B CB 1 ATOM 5412 C CG . GLU B 1 311 ? 40.652 -53.821 -31.322 1.00 94.96 ? 311 GLU B CG 1 ATOM 5413 C CD . GLU B 1 311 ? 40.919 -53.089 -30.022 1.00 137.45 ? 311 GLU B CD 1 ATOM 5414 O OE1 . GLU B 1 311 ? 41.878 -52.283 -29.969 1.00 133.55 ? 311 GLU B OE1 1 ATOM 5415 O OE2 . GLU B 1 311 ? 40.190 -53.359 -29.040 1.00 146.47 ? 311 GLU B OE2 1 ATOM 5416 N N . ILE B 1 312 ? 39.290 -55.728 -33.533 1.00 72.09 ? 312 ILE B N 1 ATOM 5417 C CA . ILE B 1 312 ? 38.039 -56.473 -33.572 1.00 72.00 ? 312 ILE B CA 1 ATOM 5418 C C . ILE B 1 312 ? 36.977 -55.603 -32.892 1.00 77.23 ? 312 ILE B C 1 ATOM 5419 O O . ILE B 1 312 ? 37.211 -55.085 -31.787 1.00 77.42 ? 312 ILE B O 1 ATOM 5420 C CB . ILE B 1 312 ? 38.096 -57.871 -32.899 1.00 74.96 ? 312 ILE B CB 1 ATOM 5421 C CG1 . ILE B 1 312 ? 39.257 -58.731 -33.426 1.00 75.94 ? 312 ILE B CG1 1 ATOM 5422 C CG2 . ILE B 1 312 ? 36.748 -58.600 -33.052 1.00 75.26 ? 312 ILE B CG2 1 ATOM 5423 C CD1 . ILE B 1 312 ? 39.358 -60.181 -32.799 1.00 90.43 ? 312 ILE B CD1 1 ATOM 5424 N N . ALA B 1 313 ? 35.847 -55.398 -33.601 1.00 71.85 ? 313 ALA B N 1 ATOM 5425 C CA . ALA B 1 313 ? 34.686 -54.666 -33.133 1.00 70.26 ? 313 ALA B CA 1 ATOM 5426 C C . ALA B 1 313 ? 33.500 -55.578 -33.277 1.00 70.96 ? 313 ALA B C 1 ATOM 5427 O O . ALA B 1 313 ? 33.398 -56.296 -34.269 1.00 68.28 ? 313 ALA B O 1 ATOM 5428 C CB . ALA B 1 313 ? 34.488 -53.412 -33.953 1.00 71.31 ? 313 ALA B CB 1 ATOM 5429 N N . GLU B 1 314 ? 32.636 -55.610 -32.251 1.00 69.44 ? 314 GLU B N 1 ATOM 5430 C CA . GLU B 1 314 ? 31.445 -56.465 -32.267 1.00 69.94 ? 314 GLU B CA 1 ATOM 5431 C C . GLU B 1 314 ? 30.215 -55.679 -32.720 1.00 74.96 ? 314 GLU B C 1 ATOM 5432 O O . GLU B 1 314 ? 29.961 -54.564 -32.233 1.00 73.40 ? 314 GLU B O 1 ATOM 5433 C CB . GLU B 1 314 ? 31.215 -57.134 -30.899 1.00 71.08 ? 314 GLU B CB 1 ATOM 5434 C CG . GLU B 1 314 ? 30.151 -58.227 -30.910 1.00 83.41 ? 314 GLU B CG 1 ATOM 5435 C CD . GLU B 1 314 ? 29.854 -58.847 -29.552 1.00 107.73 ? 314 GLU B CD 1 ATOM 5436 O OE1 . GLU B 1 314 ? 29.600 -58.081 -28.594 1.00 81.33 ? 314 GLU B OE1 1 ATOM 5437 O OE2 . GLU B 1 314 ? 29.867 -60.097 -29.442 1.00 109.11 ? 314 GLU B OE2 1 ATOM 5438 N N . THR B 1 315 ? 29.469 -56.254 -33.672 1.00 73.45 ? 315 THR B N 1 ATOM 5439 C CA . THR B 1 315 ? 28.249 -55.632 -34.176 1.00 74.33 ? 315 THR B CA 1 ATOM 5440 C C . THR B 1 315 ? 27.109 -55.910 -33.204 1.00 81.68 ? 315 THR B C 1 ATOM 5441 O O . THR B 1 315 ? 27.245 -56.742 -32.297 1.00 83.61 ? 315 THR B O 1 ATOM 5442 C CB . THR B 1 315 ? 27.914 -56.023 -35.639 1.00 72.26 ? 315 THR B CB 1 ATOM 5443 O OG1 . THR B 1 315 ? 27.303 -57.321 -35.684 1.00 54.19 ? 315 THR B OG1 1 ATOM 5444 C CG2 . THR B 1 315 ? 29.117 -55.905 -36.576 1.00 73.19 ? 315 THR B CG2 1 ATOM 5445 N N . GLN B 1 316 ? 25.976 -55.238 -33.414 1.00 76.38 ? 316 GLN B N 1 ATOM 5446 C CA . GLN B 1 316 ? 24.797 -55.382 -32.584 1.00 74.64 ? 316 GLN B CA 1 ATOM 5447 C C . GLN B 1 316 ? 24.215 -56.810 -32.596 1.00 77.18 ? 316 GLN B C 1 ATOM 5448 O O . GLN B 1 316 ? 23.482 -57.155 -31.674 1.00 75.74 ? 316 GLN B O 1 ATOM 5449 C CB . GLN B 1 316 ? 23.758 -54.312 -32.969 1.00 75.74 ? 316 GLN B CB 1 ATOM 5450 C CG . GLN B 1 316 ? 24.143 -52.926 -32.418 1.00 85.92 ? 316 GLN B CG 1 ATOM 5451 C CD . GLN B 1 316 ? 23.276 -51.784 -32.876 1.00 82.34 ? 316 GLN B CD 1 ATOM 5452 O OE1 . GLN B 1 316 ? 22.062 -51.785 -32.656 1.00 65.50 ? 316 GLN B OE1 1 ATOM 5453 N NE2 . GLN B 1 316 ? 23.905 -50.750 -33.466 1.00 69.57 ? 316 GLN B NE2 1 ATOM 5454 N N . HIS B 1 317 ? 24.598 -57.661 -33.581 1.00 74.45 ? 317 HIS B N 1 ATOM 5455 C CA . HIS B 1 317 ? 24.082 -59.037 -33.697 1.00 73.84 ? 317 HIS B CA 1 ATOM 5456 C C . HIS B 1 317 ? 25.090 -60.099 -33.283 1.00 75.54 ? 317 HIS B C 1 ATOM 5457 O O . HIS B 1 317 ? 24.970 -61.253 -33.694 1.00 73.92 ? 317 HIS B O 1 ATOM 5458 C CB . HIS B 1 317 ? 23.531 -59.297 -35.104 1.00 75.11 ? 317 HIS B CB 1 ATOM 5459 C CG . HIS B 1 317 ? 22.731 -58.145 -35.610 1.00 79.39 ? 317 HIS B CG 1 ATOM 5460 N ND1 . HIS B 1 317 ? 21.455 -57.915 -35.161 1.00 81.40 ? 317 HIS B ND1 1 ATOM 5461 C CD2 . HIS B 1 317 ? 23.103 -57.120 -36.419 1.00 82.46 ? 317 HIS B CD2 1 ATOM 5462 C CE1 . HIS B 1 317 ? 21.064 -56.792 -35.741 1.00 81.50 ? 317 HIS B CE1 1 ATOM 5463 N NE2 . HIS B 1 317 ? 22.021 -56.279 -36.511 1.00 82.19 ? 317 HIS B NE2 1 ATOM 5464 N N . GLY B 1 318 ? 26.047 -59.711 -32.441 1.00 73.19 ? 318 GLY B N 1 ATOM 5465 C CA . GLY B 1 318 ? 27.076 -60.606 -31.928 1.00 73.99 ? 318 GLY B CA 1 ATOM 5466 C C . GLY B 1 318 ? 28.238 -60.896 -32.867 1.00 80.50 ? 318 GLY B C 1 ATOM 5467 O O . GLY B 1 318 ? 29.287 -61.381 -32.411 1.00 81.88 ? 318 GLY B O 1 ATOM 5468 N N . THR B 1 319 ? 28.076 -60.595 -34.193 1.00 74.87 ? 319 THR B N 1 ATOM 5469 C CA . THR B 1 319 ? 29.108 -60.797 -35.214 1.00 72.62 ? 319 THR B CA 1 ATOM 5470 C C . THR B 1 319 ? 30.271 -59.838 -34.961 1.00 75.95 ? 319 THR B C 1 ATOM 5471 O O . THR B 1 319 ? 30.117 -58.823 -34.285 1.00 74.88 ? 319 THR B O 1 ATOM 5472 C CB . THR B 1 319 ? 28.565 -60.679 -36.645 1.00 71.51 ? 319 THR B CB 1 ATOM 5473 O OG1 . THR B 1 319 ? 28.534 -59.312 -37.030 1.00 75.19 ? 319 THR B OG1 1 ATOM 5474 C CG2 . THR B 1 319 ? 27.206 -61.332 -36.839 1.00 65.94 ? 319 THR B CG2 1 ATOM 5475 N N . ILE B 1 320 ? 31.444 -60.184 -35.475 1.00 72.28 ? 320 ILE B N 1 ATOM 5476 C CA . ILE B 1 320 ? 32.633 -59.364 -35.300 1.00 70.53 ? 320 ILE B CA 1 ATOM 5477 C C . ILE B 1 320 ? 33.205 -58.967 -36.638 1.00 72.37 ? 320 ILE B C 1 ATOM 5478 O O . ILE B 1 320 ? 32.997 -59.662 -37.642 1.00 71.56 ? 320 ILE B O 1 ATOM 5479 C CB . ILE B 1 320 ? 33.683 -60.023 -34.383 1.00 73.03 ? 320 ILE B CB 1 ATOM 5480 C CG1 . ILE B 1 320 ? 34.147 -61.406 -34.898 1.00 72.23 ? 320 ILE B CG1 1 ATOM 5481 C CG2 . ILE B 1 320 ? 33.175 -60.097 -32.961 1.00 74.84 ? 320 ILE B CG2 1 ATOM 5482 C CD1 . ILE B 1 320 ? 35.543 -61.416 -35.316 1.00 69.60 ? 320 ILE B CD1 1 ATOM 5483 N N . VAL B 1 321 ? 33.931 -57.839 -36.641 1.00 66.98 ? 321 VAL B N 1 ATOM 5484 C CA . VAL B 1 321 ? 34.568 -57.269 -37.828 1.00 64.96 ? 321 VAL B CA 1 ATOM 5485 C C . VAL B 1 321 ? 36.040 -56.987 -37.546 1.00 65.27 ? 321 VAL B C 1 ATOM 5486 O O . VAL B 1 321 ? 36.386 -56.409 -36.513 1.00 62.53 ? 321 VAL B O 1 ATOM 5487 C CB . VAL B 1 321 ? 33.800 -56.027 -38.411 1.00 67.95 ? 321 VAL B CB 1 ATOM 5488 C CG1 . VAL B 1 321 ? 34.386 -55.574 -39.757 1.00 67.33 ? 321 VAL B CG1 1 ATOM 5489 C CG2 . VAL B 1 321 ? 32.321 -56.349 -38.599 1.00 67.51 ? 321 VAL B CG2 1 ATOM 5490 N N . ILE B 1 322 ? 36.894 -57.392 -38.490 1.00 61.87 ? 322 ILE B N 1 ATOM 5491 C CA . ILE B 1 322 ? 38.328 -57.200 -38.421 1.00 61.48 ? 322 ILE B CA 1 ATOM 5492 C C . ILE B 1 322 ? 38.842 -56.588 -39.726 1.00 64.08 ? 322 ILE B C 1 ATOM 5493 O O . ILE B 1 322 ? 38.485 -57.029 -40.819 1.00 60.95 ? 322 ILE B O 1 ATOM 5494 C CB . ILE B 1 322 ? 39.028 -58.547 -38.020 1.00 64.94 ? 322 ILE B CB 1 ATOM 5495 C CG1 . ILE B 1 322 ? 40.562 -58.413 -37.882 1.00 66.00 ? 322 ILE B CG1 1 ATOM 5496 C CG2 . ILE B 1 322 ? 38.660 -59.719 -38.928 1.00 65.05 ? 322 ILE B CG2 1 ATOM 5497 C CD1 . ILE B 1 322 ? 41.027 -57.755 -36.590 1.00 77.47 ? 322 ILE B CD1 1 ATOM 5498 N N . ARG B 1 323 ? 39.690 -55.588 -39.595 1.00 63.87 ? 323 ARG B N 1 ATOM 5499 C CA . ARG B 1 323 ? 40.304 -54.973 -40.757 1.00 65.63 ? 323 ARG B CA 1 ATOM 5500 C C . ARG B 1 323 ? 41.798 -55.246 -40.665 1.00 71.14 ? 323 ARG B C 1 ATOM 5501 O O . ARG B 1 323 ? 42.429 -54.920 -39.642 1.00 67.87 ? 323 ARG B O 1 ATOM 5502 C CB . ARG B 1 323 ? 39.934 -53.478 -40.876 1.00 69.18 ? 323 ARG B CB 1 ATOM 5503 C CG . ARG B 1 323 ? 40.750 -52.651 -41.879 1.00 81.14 ? 323 ARG B CG 1 ATOM 5504 C CD . ARG B 1 323 ? 39.969 -52.135 -43.084 1.00 90.46 ? 323 ARG B CD 1 ATOM 5505 N NE . ARG B 1 323 ? 38.818 -51.286 -42.742 1.00 90.27 ? 323 ARG B NE 1 ATOM 5506 C CZ . ARG B 1 323 ? 38.868 -49.974 -42.510 1.00 93.41 ? 323 ARG B CZ 1 ATOM 5507 N NH1 . ARG B 1 323 ? 40.031 -49.326 -42.554 1.00 78.66 ? 323 ARG B NH1 1 ATOM 5508 N NH2 . ARG B 1 323 ? 37.762 -49.305 -42.221 1.00 66.17 ? 323 ARG B NH2 1 ATOM 5509 N N . VAL B 1 324 ? 42.336 -55.927 -41.724 1.00 71.90 ? 324 VAL B N 1 ATOM 5510 C CA . VAL B 1 324 ? 43.742 -56.379 -41.814 1.00 72.74 ? 324 VAL B CA 1 ATOM 5511 C C . VAL B 1 324 ? 44.453 -56.028 -43.125 1.00 83.35 ? 324 VAL B C 1 ATOM 5512 O O . VAL B 1 324 ? 43.831 -56.064 -44.187 1.00 82.68 ? 324 VAL B O 1 ATOM 5513 C CB . VAL B 1 324 ? 43.879 -57.901 -41.539 1.00 74.33 ? 324 VAL B CB 1 ATOM 5514 C CG1 . VAL B 1 324 ? 43.723 -58.214 -40.057 1.00 74.12 ? 324 VAL B CG1 1 ATOM 5515 C CG2 . VAL B 1 324 ? 42.915 -58.726 -42.387 1.00 73.28 ? 324 VAL B CG2 1 ATOM 5516 N N . GLN B 1 325 ? 45.780 -55.773 -43.049 1.00 85.44 ? 325 GLN B N 1 ATOM 5517 C CA . GLN B 1 325 ? 46.635 -55.495 -44.217 1.00 87.51 ? 325 GLN B CA 1 ATOM 5518 C C . GLN B 1 325 ? 47.639 -56.639 -44.451 1.00 97.91 ? 325 GLN B C 1 ATOM 5519 O O . GLN B 1 325 ? 48.271 -57.091 -43.494 1.00 97.06 ? 325 GLN B O 1 ATOM 5520 C CB . GLN B 1 325 ? 47.379 -54.171 -44.040 1.00 88.14 ? 325 GLN B CB 1 ATOM 5521 C CG . GLN B 1 325 ? 47.299 -53.276 -45.265 1.00 89.07 ? 325 GLN B CG 1 ATOM 5522 C CD . GLN B 1 325 ? 48.306 -52.138 -45.231 1.00 93.41 ? 325 GLN B CD 1 ATOM 5523 O OE1 . GLN B 1 325 ? 48.916 -51.814 -44.203 1.00 66.74 ? 325 GLN B OE1 1 ATOM 5524 N NE2 . GLN B 1 325 ? 48.535 -51.520 -46.382 1.00 99.94 ? 325 GLN B NE2 1 ATOM 5525 N N . TYR B 1 326 ? 47.766 -57.117 -45.712 1.00 100.21 ? 326 TYR B N 1 ATOM 5526 C CA . TYR B 1 326 ? 48.688 -58.209 -46.081 1.00 102.34 ? 326 TYR B CA 1 ATOM 5527 C C . TYR B 1 326 ? 50.088 -57.662 -46.306 1.00 109.02 ? 326 TYR B C 1 ATOM 5528 O O . TYR B 1 326 ? 50.260 -56.647 -46.991 1.00 108.09 ? 326 TYR B O 1 ATOM 5529 C CB . TYR B 1 326 ? 48.193 -58.976 -47.327 1.00 104.07 ? 326 TYR B CB 1 ATOM 5530 C CG . TYR B 1 326 ? 49.041 -60.156 -47.783 1.00 106.64 ? 326 TYR B CG 1 ATOM 5531 C CD1 . TYR B 1 326 ? 49.373 -61.188 -46.904 1.00 108.35 ? 326 TYR B CD1 1 ATOM 5532 C CD2 . TYR B 1 326 ? 49.396 -60.307 -49.123 1.00 108.01 ? 326 TYR B CD2 1 ATOM 5533 C CE1 . TYR B 1 326 ? 50.060 -62.321 -47.343 1.00 109.24 ? 326 TYR B CE1 1 ATOM 5534 C CE2 . TYR B 1 326 ? 50.093 -61.431 -49.571 1.00 108.88 ? 326 TYR B CE2 1 ATOM 5535 C CZ . TYR B 1 326 ? 50.425 -62.435 -48.677 1.00 116.09 ? 326 TYR B CZ 1 ATOM 5536 O OH . TYR B 1 326 ? 51.146 -63.519 -49.125 1.00 116.33 ? 326 TYR B OH 1 ATOM 5537 N N . GLU B 1 327 ? 51.086 -58.337 -45.721 1.00 107.60 ? 327 GLU B N 1 ATOM 5538 C CA . GLU B 1 327 ? 52.482 -57.917 -45.820 1.00 107.91 ? 327 GLU B CA 1 ATOM 5539 C C . GLU B 1 327 ? 53.361 -58.901 -46.606 1.00 113.57 ? 327 GLU B C 1 ATOM 5540 O O . GLU B 1 327 ? 54.586 -58.740 -46.632 1.00 113.34 ? 327 GLU B O 1 ATOM 5541 C CB . GLU B 1 327 ? 53.043 -57.626 -44.424 1.00 108.97 ? 327 GLU B CB 1 ATOM 5542 C CG . GLU B 1 327 ? 52.376 -56.421 -43.791 1.00 115.68 ? 327 GLU B CG 1 ATOM 5543 C CD . GLU B 1 327 ? 52.712 -56.208 -42.334 1.00 124.22 ? 327 GLU B CD 1 ATOM 5544 O OE1 . GLU B 1 327 ? 52.362 -57.076 -41.502 1.00 116.17 ? 327 GLU B OE1 1 ATOM 5545 O OE2 . GLU B 1 327 ? 53.281 -55.142 -42.015 1.00 110.73 ? 327 GLU B OE2 1 ATOM 5546 N N . GLY B 1 328 ? 52.717 -59.869 -47.270 1.00 110.80 ? 328 GLY B N 1 ATOM 5547 C CA . GLY B 1 328 ? 53.360 -60.902 -48.075 1.00 110.68 ? 328 GLY B CA 1 ATOM 5548 C C . GLY B 1 328 ? 53.520 -60.498 -49.522 1.00 115.57 ? 328 GLY B C 1 ATOM 5549 O O . GLY B 1 328 ? 53.551 -59.298 -49.815 1.00 114.88 ? 328 GLY B O 1 ATOM 5550 N N . ASP B 1 329 ? 53.635 -61.485 -50.445 1.00 113.49 ? 329 ASP B N 1 ATOM 5551 C CA . ASP B 1 329 ? 53.877 -61.188 -51.866 1.00 113.70 ? 329 ASP B CA 1 ATOM 5552 C C . ASP B 1 329 ? 52.944 -61.885 -52.889 1.00 116.76 ? 329 ASP B C 1 ATOM 5553 O O . ASP B 1 329 ? 52.826 -61.392 -54.018 1.00 116.39 ? 329 ASP B O 1 ATOM 5554 C CB . ASP B 1 329 ? 55.350 -61.471 -52.244 1.00 115.86 ? 329 ASP B CB 1 ATOM 5555 C CG . ASP B 1 329 ? 56.394 -60.717 -51.430 1.00 127.37 ? 329 ASP B CG 1 ATOM 5556 O OD1 . ASP B 1 329 ? 56.711 -59.550 -51.788 1.00 132.65 ? 329 ASP B OD1 1 ATOM 5557 O OD2 . ASP B 1 329 ? 56.910 -61.296 -50.445 1.00 127.90 ? 329 ASP B OD2 1 ATOM 5558 N N . GLY B 1 330 ? 52.313 -62.994 -52.501 1.00 112.22 ? 330 GLY B N 1 ATOM 5559 C CA . GLY B 1 330 ? 51.445 -63.791 -53.370 1.00 111.67 ? 330 GLY B CA 1 ATOM 5560 C C . GLY B 1 330 ? 50.244 -63.139 -54.046 1.00 114.12 ? 330 GLY B C 1 ATOM 5561 O O . GLY B 1 330 ? 49.756 -63.675 -55.050 1.00 114.02 ? 330 GLY B O 1 ATOM 5562 N N . SER B 1 331 ? 49.722 -62.017 -53.469 1.00 108.40 ? 331 SER B N 1 ATOM 5563 C CA . SER B 1 331 ? 48.543 -61.258 -53.916 1.00 106.71 ? 331 SER B CA 1 ATOM 5564 C C . SER B 1 331 ? 48.409 -61.099 -55.458 1.00 108.31 ? 331 SER B C 1 ATOM 5565 O O . SER B 1 331 ? 49.411 -60.796 -56.105 1.00 107.33 ? 331 SER B O 1 ATOM 5566 C CB . SER B 1 331 ? 48.506 -59.900 -53.235 1.00 109.13 ? 331 SER B CB 1 ATOM 5567 O OG . SER B 1 331 ? 49.643 -59.161 -53.634 1.00 115.34 ? 331 SER B OG 1 ATOM 5568 N N . PRO B 1 332 ? 47.216 -61.342 -56.069 1.00 104.08 ? 332 PRO B N 1 ATOM 5569 C CA . PRO B 1 332 ? 45.938 -61.703 -55.433 1.00 103.96 ? 332 PRO B CA 1 ATOM 5570 C C . PRO B 1 332 ? 45.914 -63.110 -54.852 1.00 108.59 ? 332 PRO B C 1 ATOM 5571 O O . PRO B 1 332 ? 46.264 -64.079 -55.538 1.00 108.79 ? 332 PRO B O 1 ATOM 5572 C CB . PRO B 1 332 ? 44.908 -61.472 -56.546 1.00 105.50 ? 332 PRO B CB 1 ATOM 5573 C CG . PRO B 1 332 ? 45.655 -61.743 -57.796 1.00 109.78 ? 332 PRO B CG 1 ATOM 5574 C CD . PRO B 1 332 ? 47.059 -61.227 -57.533 1.00 105.46 ? 332 PRO B CD 1 ATOM 5575 N N . CYS B 1 333 ? 45.553 -63.204 -53.554 1.00 104.25 ? 333 CYS B N 1 ATOM 5576 C CA . CYS B 1 333 ? 45.505 -64.477 -52.835 1.00 103.32 ? 333 CYS B CA 1 ATOM 5577 C C . CYS B 1 333 ? 44.360 -64.564 -51.802 1.00 103.12 ? 333 CYS B C 1 ATOM 5578 O O . CYS B 1 333 ? 43.892 -63.533 -51.317 1.00 103.14 ? 333 CYS B O 1 ATOM 5579 C CB . CYS B 1 333 ? 46.864 -64.801 -52.208 1.00 103.93 ? 333 CYS B CB 1 ATOM 5580 S SG . CYS B 1 333 ? 47.468 -63.566 -51.023 1.00 108.15 ? 333 CYS B SG 1 ATOM 5581 N N . LYS B 1 334 ? 43.924 -65.799 -51.464 1.00 95.83 ? 334 LYS B N 1 ATOM 5582 C CA . LYS B 1 334 ? 42.902 -66.065 -50.438 1.00 93.73 ? 334 LYS B CA 1 ATOM 5583 C C . LYS B 1 334 ? 43.522 -65.870 -49.027 1.00 94.21 ? 334 LYS B C 1 ATOM 5584 O O . LYS B 1 334 ? 44.522 -66.529 -48.697 1.00 92.61 ? 334 LYS B O 1 ATOM 5585 C CB . LYS B 1 334 ? 42.380 -67.520 -50.525 1.00 95.02 ? 334 LYS B CB 1 ATOM 5586 C CG . LYS B 1 334 ? 41.561 -67.924 -51.747 1.00 91.20 ? 334 LYS B CG 1 ATOM 5587 C CD . LYS B 1 334 ? 41.113 -69.375 -51.541 1.00 89.06 ? 334 LYS B CD 1 ATOM 5588 C CE . LYS B 1 334 ? 40.503 -70.029 -52.753 1.00 86.95 ? 334 LYS B CE 1 ATOM 5589 N NZ . LYS B 1 334 ? 39.816 -71.311 -52.411 1.00 90.77 ? 334 LYS B NZ 1 ATOM 5590 N N . ILE B 1 335 ? 42.922 -64.993 -48.193 1.00 89.58 ? 335 ILE B N 1 ATOM 5591 C CA . ILE B 1 335 ? 43.376 -64.791 -46.812 1.00 88.95 ? 335 ILE B CA 1 ATOM 5592 C C . ILE B 1 335 ? 42.930 -66.016 -46.009 1.00 93.17 ? 335 ILE B C 1 ATOM 5593 O O . ILE B 1 335 ? 41.731 -66.337 -46.032 1.00 92.28 ? 335 ILE B O 1 ATOM 5594 C CB . ILE B 1 335 ? 42.778 -63.541 -46.143 1.00 91.70 ? 335 ILE B CB 1 ATOM 5595 C CG1 . ILE B 1 335 ? 42.855 -62.309 -47.029 1.00 92.29 ? 335 ILE B CG1 1 ATOM 5596 C CG2 . ILE B 1 335 ? 43.420 -63.310 -44.785 1.00 92.50 ? 335 ILE B CG2 1 ATOM 5597 C CD1 . ILE B 1 335 ? 41.673 -61.381 -46.879 1.00 98.93 ? 335 ILE B CD1 1 ATOM 5598 N N . PRO B 1 336 ? 43.849 -66.711 -45.287 1.00 89.32 ? 336 PRO B N 1 ATOM 5599 C CA . PRO B 1 336 ? 43.414 -67.865 -44.484 1.00 88.00 ? 336 PRO B CA 1 ATOM 5600 C C . PRO B 1 336 ? 42.672 -67.359 -43.245 1.00 88.11 ? 336 PRO B C 1 ATOM 5601 O O . PRO B 1 336 ? 43.128 -66.428 -42.573 1.00 86.03 ? 336 PRO B O 1 ATOM 5602 C CB . PRO B 1 336 ? 44.736 -68.583 -44.131 1.00 89.91 ? 336 PRO B CB 1 ATOM 5603 C CG . PRO B 1 336 ? 45.809 -67.893 -44.950 1.00 94.71 ? 336 PRO B CG 1 ATOM 5604 C CD . PRO B 1 336 ? 45.306 -66.499 -45.155 1.00 90.59 ? 336 PRO B CD 1 ATOM 5605 N N . PHE B 1 337 ? 41.499 -67.937 -42.979 1.00 83.72 ? 337 PHE B N 1 ATOM 5606 C CA . PHE B 1 337 ? 40.702 -67.505 -41.837 1.00 82.94 ? 337 PHE B CA 1 ATOM 5607 C C . PHE B 1 337 ? 40.025 -68.668 -41.154 1.00 89.06 ? 337 PHE B C 1 ATOM 5608 O O . PHE B 1 337 ? 39.451 -69.536 -41.824 1.00 87.52 ? 337 PHE B O 1 ATOM 5609 C CB . PHE B 1 337 ? 39.656 -66.472 -42.272 1.00 83.55 ? 337 PHE B CB 1 ATOM 5610 C CG . PHE B 1 337 ? 39.026 -65.701 -41.140 1.00 83.80 ? 337 PHE B CG 1 ATOM 5611 C CD1 . PHE B 1 337 ? 39.644 -64.567 -40.618 1.00 84.45 ? 337 PHE B CD1 1 ATOM 5612 C CD2 . PHE B 1 337 ? 37.803 -66.088 -40.608 1.00 86.23 ? 337 PHE B CD2 1 ATOM 5613 C CE1 . PHE B 1 337 ? 39.056 -63.840 -39.578 1.00 86.76 ? 337 PHE B CE1 1 ATOM 5614 C CE2 . PHE B 1 337 ? 37.220 -65.367 -39.560 1.00 87.17 ? 337 PHE B CE2 1 ATOM 5615 C CZ . PHE B 1 337 ? 37.852 -64.243 -39.054 1.00 85.55 ? 337 PHE B CZ 1 ATOM 5616 N N . GLU B 1 338 ? 40.077 -68.656 -39.802 1.00 88.30 ? 338 GLU B N 1 ATOM 5617 C CA . GLU B 1 338 ? 39.453 -69.659 -38.942 1.00 89.14 ? 338 GLU B CA 1 ATOM 5618 C C . GLU B 1 338 ? 39.128 -69.139 -37.539 1.00 94.83 ? 338 GLU B C 1 ATOM 5619 O O . GLU B 1 338 ? 39.843 -68.300 -36.983 1.00 92.52 ? 338 GLU B O 1 ATOM 5620 C CB . GLU B 1 338 ? 40.309 -70.923 -38.867 1.00 90.82 ? 338 GLU B CB 1 ATOM 5621 C CG . GLU B 1 338 ? 39.463 -72.176 -38.881 1.00 105.78 ? 338 GLU B CG 1 ATOM 5622 C CD . GLU B 1 338 ? 39.999 -73.325 -39.713 1.00 138.13 ? 338 GLU B CD 1 ATOM 5623 O OE1 . GLU B 1 338 ? 40.726 -74.179 -39.151 1.00 143.32 ? 338 GLU B OE1 1 ATOM 5624 O OE2 . GLU B 1 338 ? 39.589 -73.438 -40.893 1.00 128.46 ? 338 GLU B OE2 1 ATOM 5625 N N . ILE B 1 339 ? 37.999 -69.615 -36.999 1.00 96.06 ? 339 ILE B N 1 ATOM 5626 C CA . ILE B 1 339 ? 37.528 -69.324 -35.640 1.00 98.48 ? 339 ILE B CA 1 ATOM 5627 C C . ILE B 1 339 ? 37.414 -70.691 -34.950 1.00 107.47 ? 339 ILE B C 1 ATOM 5628 O O . ILE B 1 339 ? 36.310 -71.200 -34.746 1.00 107.73 ? 339 ILE B O 1 ATOM 5629 C CB . ILE B 1 339 ? 36.185 -68.517 -35.534 1.00 101.58 ? 339 ILE B CB 1 ATOM 5630 C CG1 . ILE B 1 339 ? 36.003 -67.484 -36.658 1.00 101.79 ? 339 ILE B CG1 1 ATOM 5631 C CG2 . ILE B 1 339 ? 36.053 -67.864 -34.149 1.00 101.68 ? 339 ILE B CG2 1 ATOM 5632 C CD1 . ILE B 1 339 ? 34.560 -67.167 -36.929 1.00 105.23 ? 339 ILE B CD1 1 ATOM 5633 N N . THR B 1 340 ? 38.563 -71.306 -34.645 1.00 106.61 ? 340 THR B N 1 ATOM 5634 C CA . THR B 1 340 ? 38.640 -72.616 -33.981 1.00 107.19 ? 340 THR B CA 1 ATOM 5635 C C . THR B 1 340 ? 38.489 -72.451 -32.453 1.00 111.90 ? 340 THR B C 1 ATOM 5636 O O . THR B 1 340 ? 38.366 -71.323 -31.961 1.00 112.13 ? 340 THR B O 1 ATOM 5637 C CB . THR B 1 340 ? 39.988 -73.304 -34.318 1.00 115.13 ? 340 THR B CB 1 ATOM 5638 O OG1 . THR B 1 340 ? 41.041 -72.338 -34.260 1.00 115.17 ? 340 THR B OG1 1 ATOM 5639 C CG2 . THR B 1 340 ? 39.980 -74.015 -35.666 1.00 112.46 ? 340 THR B CG2 1 ATOM 5640 N N . ASP B 1 341 ? 38.546 -73.572 -31.701 1.00 107.75 ? 341 ASP B N 1 ATOM 5641 C CA . ASP B 1 341 ? 38.493 -73.567 -30.233 1.00 106.75 ? 341 ASP B CA 1 ATOM 5642 C C . ASP B 1 341 ? 39.777 -72.935 -29.602 1.00 110.06 ? 341 ASP B C 1 ATOM 5643 O O . ASP B 1 341 ? 40.612 -72.337 -30.308 1.00 108.29 ? 341 ASP B O 1 ATOM 5644 C CB . ASP B 1 341 ? 38.169 -74.982 -29.645 1.00 107.53 ? 341 ASP B CB 1 ATOM 5645 C CG . ASP B 1 341 ? 38.567 -76.213 -30.465 1.00 105.81 ? 341 ASP B CG 1 ATOM 5646 O OD1 . ASP B 1 341 ? 39.566 -76.141 -31.200 1.00 104.02 ? 341 ASP B OD1 1 ATOM 5647 O OD2 . ASP B 1 341 ? 37.914 -77.264 -30.313 1.00 106.26 ? 341 ASP B OD2 1 ATOM 5648 N N . LEU B 1 342 ? 39.897 -73.042 -28.265 1.00 106.90 ? 342 LEU B N 1 ATOM 5649 C CA . LEU B 1 342 ? 41.039 -72.533 -27.504 1.00 106.57 ? 342 LEU B CA 1 ATOM 5650 C C . LEU B 1 342 ? 42.215 -73.496 -27.713 1.00 111.59 ? 342 LEU B C 1 ATOM 5651 O O . LEU B 1 342 ? 43.381 -73.079 -27.757 1.00 111.81 ? 342 LEU B O 1 ATOM 5652 C CB . LEU B 1 342 ? 40.671 -72.413 -26.014 1.00 106.07 ? 342 LEU B CB 1 ATOM 5653 C CG . LEU B 1 342 ? 39.576 -71.395 -25.671 1.00 109.31 ? 342 LEU B CG 1 ATOM 5654 C CD1 . LEU B 1 342 ? 38.228 -72.080 -25.443 1.00 109.04 ? 342 LEU B CD1 1 ATOM 5655 C CD2 . LEU B 1 342 ? 39.969 -70.579 -24.471 1.00 110.41 ? 342 LEU B CD2 1 ATOM 5656 N N . GLU B 1 343 ? 41.872 -74.788 -27.893 1.00 107.43 ? 343 GLU B N 1 ATOM 5657 C CA . GLU B 1 343 ? 42.778 -75.895 -28.161 1.00 106.87 ? 343 GLU B CA 1 ATOM 5658 C C . GLU B 1 343 ? 43.445 -75.759 -29.547 1.00 109.98 ? 343 GLU B C 1 ATOM 5659 O O . GLU B 1 343 ? 44.655 -75.958 -29.651 1.00 110.43 ? 343 GLU B O 1 ATOM 5660 C CB . GLU B 1 343 ? 42.004 -77.225 -28.094 1.00 108.18 ? 343 GLU B CB 1 ATOM 5661 C CG . GLU B 1 343 ? 41.649 -77.675 -26.688 1.00 118.23 ? 343 GLU B CG 1 ATOM 5662 C CD . GLU B 1 343 ? 41.322 -79.151 -26.559 1.00 137.09 ? 343 GLU B CD 1 ATOM 5663 O OE1 . GLU B 1 343 ? 40.642 -79.694 -27.461 1.00 139.05 ? 343 GLU B OE1 1 ATOM 5664 O OE2 . GLU B 1 343 ? 41.755 -79.767 -25.555 1.00 109.93 ? 343 GLU B OE2 1 ATOM 5665 N N . LYS B 1 344 ? 42.637 -75.428 -30.596 1.00 104.13 ? 344 LYS B N 1 ATOM 5666 C CA . LYS B 1 344 ? 42.945 -75.286 -32.033 1.00 102.82 ? 344 LYS B CA 1 ATOM 5667 C C . LYS B 1 344 ? 42.435 -76.491 -32.835 1.00 106.46 ? 344 LYS B C 1 ATOM 5668 O O . LYS B 1 344 ? 42.604 -76.543 -34.061 1.00 105.14 ? 344 LYS B O 1 ATOM 5669 C CB . LYS B 1 344 ? 44.428 -75.006 -32.328 1.00 104.22 ? 344 LYS B CB 1 ATOM 5670 C CG . LYS B 1 344 ? 44.873 -73.574 -32.026 1.00 106.70 ? 344 LYS B CG 1 ATOM 5671 C CD . LYS B 1 344 ? 46.219 -73.253 -32.677 1.00 104.90 ? 344 LYS B CD 1 ATOM 5672 C CE . LYS B 1 344 ? 46.140 -73.182 -34.187 1.00 98.65 ? 344 LYS B CE 1 ATOM 5673 N NZ . LYS B 1 344 ? 47.478 -72.989 -34.800 1.00 105.43 ? 344 LYS B NZ 1 ATOM 5674 N N . ARG B 1 345 ? 41.786 -77.440 -32.123 1.00 103.97 ? 345 ARG B N 1 ATOM 5675 C CA . ARG B 1 345 ? 41.198 -78.688 -32.612 1.00 104.31 ? 345 ARG B CA 1 ATOM 5676 C C . ARG B 1 345 ? 40.301 -78.491 -33.831 1.00 108.52 ? 345 ARG B C 1 ATOM 5677 O O . ARG B 1 345 ? 40.811 -78.498 -34.952 1.00 106.59 ? 345 ARG B O 1 ATOM 5678 C CB . ARG B 1 345 ? 40.465 -79.419 -31.460 1.00 105.77 ? 345 ARG B CB 1 ATOM 5679 C CG . ARG B 1 345 ? 40.432 -80.950 -31.586 1.00 119.91 ? 345 ARG B CG 1 ATOM 5680 C CD . ARG B 1 345 ? 41.746 -81.552 -32.112 1.00 130.64 ? 345 ARG B CD 1 ATOM 5681 N NE . ARG B 1 345 ? 42.481 -82.349 -31.124 1.00 131.38 ? 345 ARG B NE 1 ATOM 5682 C CZ . ARG B 1 345 ? 43.804 -82.499 -31.112 1.00 135.99 ? 345 ARG B CZ 1 ATOM 5683 N NH1 . ARG B 1 345 ? 44.560 -81.877 -32.013 1.00 119.43 ? 345 ARG B NH1 1 ATOM 5684 N NH2 . ARG B 1 345 ? 44.384 -83.254 -30.189 1.00 116.60 ? 345 ARG B NH2 1 ATOM 5685 N N . HIS B 1 346 ? 38.979 -78.285 -33.618 1.00 107.53 ? 346 HIS B N 1 ATOM 5686 C CA . HIS B 1 346 ? 38.004 -78.046 -34.698 1.00 107.97 ? 346 HIS B CA 1 ATOM 5687 C C . HIS B 1 346 ? 37.559 -76.574 -34.846 1.00 111.52 ? 346 HIS B C 1 ATOM 5688 O O . HIS B 1 346 ? 37.674 -75.768 -33.923 1.00 110.26 ? 346 HIS B O 1 ATOM 5689 C CB . HIS B 1 346 ? 36.745 -78.968 -34.631 1.00 108.81 ? 346 HIS B CB 1 ATOM 5690 C CG . HIS B 1 346 ? 36.432 -79.614 -33.311 1.00 112.21 ? 346 HIS B CG 1 ATOM 5691 N ND1 . HIS B 1 346 ? 36.687 -78.984 -32.102 1.00 113.99 ? 346 HIS B ND1 1 ATOM 5692 C CD2 . HIS B 1 346 ? 35.827 -80.799 -33.062 1.00 113.85 ? 346 HIS B CD2 1 ATOM 5693 C CE1 . HIS B 1 346 ? 36.260 -79.816 -31.165 1.00 113.36 ? 346 HIS B CE1 1 ATOM 5694 N NE2 . HIS B 1 346 ? 35.734 -80.920 -31.694 1.00 113.62 ? 346 HIS B NE2 1 ATOM 5695 N N . VAL B 1 347 ? 37.051 -76.256 -36.046 1.00 108.70 ? 347 VAL B N 1 ATOM 5696 C CA . VAL B 1 347 ? 36.465 -74.979 -36.474 1.00 108.08 ? 347 VAL B CA 1 ATOM 5697 C C . VAL B 1 347 ? 35.176 -74.748 -35.638 1.00 110.27 ? 347 VAL B C 1 ATOM 5698 O O . VAL B 1 347 ? 34.475 -75.722 -35.325 1.00 110.64 ? 347 VAL B O 1 ATOM 5699 C CB . VAL B 1 347 ? 36.180 -74.991 -38.018 1.00 111.82 ? 347 VAL B CB 1 ATOM 5700 C CG1 . VAL B 1 347 ? 37.456 -75.218 -38.816 1.00 111.38 ? 347 VAL B CG1 1 ATOM 5701 C CG2 . VAL B 1 347 ? 35.131 -76.041 -38.411 1.00 111.70 ? 347 VAL B CG2 1 ATOM 5702 N N . LEU B 1 348 ? 34.880 -73.496 -35.247 1.00 103.96 ? 348 LEU B N 1 ATOM 5703 C CA . LEU B 1 348 ? 33.675 -73.252 -34.450 1.00 102.37 ? 348 LEU B CA 1 ATOM 5704 C C . LEU B 1 348 ? 32.701 -72.271 -35.093 1.00 104.61 ? 348 LEU B C 1 ATOM 5705 O O . LEU B 1 348 ? 31.617 -72.696 -35.516 1.00 104.96 ? 348 LEU B O 1 ATOM 5706 C CB . LEU B 1 348 ? 34.003 -72.850 -33.008 1.00 101.90 ? 348 LEU B CB 1 ATOM 5707 C CG . LEU B 1 348 ? 34.009 -74.009 -32.044 1.00 105.64 ? 348 LEU B CG 1 ATOM 5708 C CD1 . LEU B 1 348 ? 35.332 -74.665 -32.034 1.00 106.03 ? 348 LEU B CD1 1 ATOM 5709 C CD2 . LEU B 1 348 ? 33.644 -73.570 -30.646 1.00 106.88 ? 348 LEU B CD2 1 ATOM 5710 N N . GLY B 1 349 ? 33.078 -70.993 -35.151 1.00 98.76 ? 349 GLY B N 1 ATOM 5711 C CA . GLY B 1 349 ? 32.248 -69.948 -35.739 1.00 97.49 ? 349 GLY B CA 1 ATOM 5712 C C . GLY B 1 349 ? 32.291 -69.939 -37.254 1.00 98.12 ? 349 GLY B C 1 ATOM 5713 O O . GLY B 1 349 ? 33.257 -70.455 -37.838 1.00 97.19 ? 349 GLY B O 1 ATOM 5714 N N . ARG B 1 350 ? 31.243 -69.329 -37.906 1.00 92.27 ? 350 ARG B N 1 ATOM 5715 C CA . ARG B 1 350 ? 31.164 -69.250 -39.378 1.00 90.29 ? 350 ARG B CA 1 ATOM 5716 C C . ARG B 1 350 ? 31.663 -67.915 -39.950 1.00 89.67 ? 350 ARG B C 1 ATOM 5717 O O . ARG B 1 350 ? 31.810 -66.929 -39.215 1.00 90.12 ? 350 ARG B O 1 ATOM 5718 C CB . ARG B 1 350 ? 29.746 -69.594 -39.910 1.00 89.83 ? 350 ARG B CB 1 ATOM 5719 C CG . ARG B 1 350 ? 28.642 -68.567 -39.633 1.00 95.87 ? 350 ARG B CG 1 ATOM 5720 C CD . ARG B 1 350 ? 27.438 -68.859 -40.505 1.00 102.59 ? 350 ARG B CD 1 ATOM 5721 N NE . ARG B 1 350 ? 26.333 -67.926 -40.266 1.00 113.55 ? 350 ARG B NE 1 ATOM 5722 C CZ . ARG B 1 350 ? 25.247 -68.201 -39.543 1.00 123.21 ? 350 ARG B CZ 1 ATOM 5723 N NH1 . ARG B 1 350 ? 25.106 -69.395 -38.969 1.00 107.15 ? 350 ARG B NH1 1 ATOM 5724 N NH2 . ARG B 1 350 ? 24.292 -67.285 -39.391 1.00 100.68 ? 350 ARG B NH2 1 ATOM 5725 N N . LEU B 1 351 ? 31.922 -67.902 -41.268 1.00 81.76 ? 351 LEU B N 1 ATOM 5726 C CA . LEU B 1 351 ? 32.328 -66.679 -41.954 1.00 79.45 ? 351 LEU B CA 1 ATOM 5727 C C . LEU B 1 351 ? 31.123 -66.025 -42.627 1.00 81.39 ? 351 LEU B C 1 ATOM 5728 O O . LEU B 1 351 ? 30.295 -66.720 -43.250 1.00 78.61 ? 351 LEU B O 1 ATOM 5729 C CB . LEU B 1 351 ? 33.427 -66.927 -43.016 1.00 78.28 ? 351 LEU B CB 1 ATOM 5730 C CG . LEU B 1 351 ? 34.710 -66.094 -42.902 1.00 80.53 ? 351 LEU B CG 1 ATOM 5731 C CD1 . LEU B 1 351 ? 35.689 -66.501 -43.941 1.00 80.29 ? 351 LEU B CD1 1 ATOM 5732 C CD2 . LEU B 1 351 ? 34.452 -64.628 -43.031 1.00 79.32 ? 351 LEU B CD2 1 ATOM 5733 N N . ILE B 1 352 ? 31.022 -64.680 -42.478 1.00 77.95 ? 352 ILE B N 1 ATOM 5734 C CA . ILE B 1 352 ? 30.002 -63.932 -43.201 1.00 77.47 ? 352 ILE B CA 1 ATOM 5735 C C . ILE B 1 352 ? 30.653 -63.499 -44.525 1.00 78.86 ? 352 ILE B C 1 ATOM 5736 O O . ILE B 1 352 ? 30.163 -63.912 -45.580 1.00 79.24 ? 352 ILE B O 1 ATOM 5737 C CB . ILE B 1 352 ? 29.337 -62.769 -42.416 1.00 80.93 ? 352 ILE B CB 1 ATOM 5738 C CG1 . ILE B 1 352 ? 28.841 -63.209 -41.000 1.00 81.52 ? 352 ILE B CG1 1 ATOM 5739 C CG2 . ILE B 1 352 ? 28.223 -62.110 -43.242 1.00 81.86 ? 352 ILE B CG2 1 ATOM 5740 C CD1 . ILE B 1 352 ? 27.664 -64.218 -40.906 1.00 84.86 ? 352 ILE B CD1 1 ATOM 5741 N N . THR B 1 353 ? 31.791 -62.748 -44.471 1.00 71.15 ? 353 THR B N 1 ATOM 5742 C CA . THR B 1 353 ? 32.547 -62.321 -45.664 1.00 69.36 ? 353 THR B CA 1 ATOM 5743 C C . THR B 1 353 ? 33.307 -63.545 -46.238 1.00 67.36 ? 353 THR B C 1 ATOM 5744 O O . THR B 1 353 ? 34.532 -63.625 -46.113 1.00 65.22 ? 353 THR B O 1 ATOM 5745 C CB . THR B 1 353 ? 33.513 -61.153 -45.310 1.00 84.83 ? 353 THR B CB 1 ATOM 5746 O OG1 . THR B 1 353 ? 32.886 -60.238 -44.412 1.00 89.35 ? 353 THR B OG1 1 ATOM 5747 C CG2 . THR B 1 353 ? 34.048 -60.420 -46.544 1.00 82.45 ? 353 THR B CG2 1 ATOM 5748 N N . VAL B 1 354 ? 32.567 -64.500 -46.848 1.00 61.61 ? 354 VAL B N 1 ATOM 5749 C CA . VAL B 1 354 ? 33.103 -65.743 -47.411 1.00 60.84 ? 354 VAL B CA 1 ATOM 5750 C C . VAL B 1 354 ? 34.188 -65.487 -48.469 1.00 70.99 ? 354 VAL B C 1 ATOM 5751 O O . VAL B 1 354 ? 34.091 -64.512 -49.235 1.00 72.51 ? 354 VAL B O 1 ATOM 5752 C CB . VAL B 1 354 ? 32.044 -66.757 -47.933 1.00 61.92 ? 354 VAL B CB 1 ATOM 5753 C CG1 . VAL B 1 354 ? 31.004 -67.102 -46.883 1.00 60.99 ? 354 VAL B CG1 1 ATOM 5754 C CG2 . VAL B 1 354 ? 31.396 -66.298 -49.222 1.00 61.19 ? 354 VAL B CG2 1 ATOM 5755 N N . ASN B 1 355 ? 35.197 -66.408 -48.511 1.00 68.41 ? 355 ASN B N 1 ATOM 5756 C CA . ASN B 1 355 ? 36.367 -66.414 -49.395 1.00 68.47 ? 355 ASN B CA 1 ATOM 5757 C C . ASN B 1 355 ? 37.117 -65.076 -49.372 1.00 71.49 ? 355 ASN B C 1 ATOM 5758 O O . ASN B 1 355 ? 37.233 -64.442 -50.423 1.00 71.56 ? 355 ASN B O 1 ATOM 5759 C CB . ASN B 1 355 ? 35.998 -66.852 -50.813 1.00 72.07 ? 355 ASN B CB 1 ATOM 5760 C CG . ASN B 1 355 ? 37.181 -67.355 -51.602 1.00 110.73 ? 355 ASN B CG 1 ATOM 5761 O OD1 . ASN B 1 355 ? 37.719 -68.444 -51.340 1.00 118.16 ? 355 ASN B OD1 1 ATOM 5762 N ND2 . ASN B 1 355 ? 37.615 -66.565 -52.577 1.00 96.47 ? 355 ASN B ND2 1 ATOM 5763 N N . PRO B 1 356 ? 37.579 -64.596 -48.185 1.00 67.85 ? 356 PRO B N 1 ATOM 5764 C CA . PRO B 1 356 ? 38.256 -63.296 -48.138 1.00 68.81 ? 356 PRO B CA 1 ATOM 5765 C C . PRO B 1 356 ? 39.531 -63.301 -48.958 1.00 76.56 ? 356 PRO B C 1 ATOM 5766 O O . PRO B 1 356 ? 40.315 -64.234 -48.839 1.00 78.24 ? 356 PRO B O 1 ATOM 5767 C CB . PRO B 1 356 ? 38.502 -63.066 -46.641 1.00 70.59 ? 356 PRO B CB 1 ATOM 5768 C CG . PRO B 1 356 ? 38.476 -64.403 -46.034 1.00 74.90 ? 356 PRO B CG 1 ATOM 5769 C CD . PRO B 1 356 ? 37.513 -65.201 -46.843 1.00 69.95 ? 356 PRO B CD 1 ATOM 5770 N N . ILE B 1 357 ? 39.686 -62.321 -49.860 1.00 74.16 ? 357 ILE B N 1 ATOM 5771 C CA . ILE B 1 357 ? 40.847 -62.260 -50.747 1.00 74.29 ? 357 ILE B CA 1 ATOM 5772 C C . ILE B 1 357 ? 41.612 -60.918 -50.690 1.00 82.51 ? 357 ILE B C 1 ATOM 5773 O O . ILE B 1 357 ? 41.042 -59.889 -50.316 1.00 84.28 ? 357 ILE B O 1 ATOM 5774 C CB . ILE B 1 357 ? 40.458 -62.628 -52.204 1.00 76.50 ? 357 ILE B CB 1 ATOM 5775 C CG1 . ILE B 1 357 ? 39.537 -61.584 -52.845 1.00 77.84 ? 357 ILE B CG1 1 ATOM 5776 C CG2 . ILE B 1 357 ? 39.872 -64.036 -52.321 1.00 74.75 ? 357 ILE B CG2 1 ATOM 5777 C CD1 . ILE B 1 357 ? 39.935 -61.163 -54.294 1.00 87.17 ? 357 ILE B CD1 1 ATOM 5778 N N . VAL B 1 358 ? 42.907 -60.942 -51.045 1.00 79.51 ? 358 VAL B N 1 ATOM 5779 C CA . VAL B 1 358 ? 43.745 -59.739 -51.144 1.00 79.74 ? 358 VAL B CA 1 ATOM 5780 C C . VAL B 1 358 ? 43.820 -59.474 -52.636 1.00 89.57 ? 358 VAL B C 1 ATOM 5781 O O . VAL B 1 358 ? 43.898 -60.420 -53.424 1.00 89.70 ? 358 VAL B O 1 ATOM 5782 C CB . VAL B 1 358 ? 45.168 -59.859 -50.512 1.00 81.81 ? 358 VAL B CB 1 ATOM 5783 C CG1 . VAL B 1 358 ? 45.898 -58.519 -50.508 1.00 80.58 ? 358 VAL B CG1 1 ATOM 5784 C CG2 . VAL B 1 358 ? 45.117 -60.433 -49.101 1.00 81.50 ? 358 VAL B CG2 1 ATOM 5785 N N . THR B 1 359 ? 43.738 -58.201 -53.022 1.00 89.93 ? 359 THR B N 1 ATOM 5786 C CA . THR B 1 359 ? 43.793 -57.768 -54.418 1.00 91.40 ? 359 THR B CA 1 ATOM 5787 C C . THR B 1 359 ? 45.085 -56.970 -54.620 1.00 100.38 ? 359 THR B C 1 ATOM 5788 O O . THR B 1 359 ? 45.782 -57.165 -55.620 1.00 101.41 ? 359 THR B O 1 ATOM 5789 C CB . THR B 1 359 ? 42.466 -57.085 -54.795 1.00 94.47 ? 359 THR B CB 1 ATOM 5790 O OG1 . THR B 1 359 ? 41.514 -58.122 -55.103 1.00 90.36 ? 359 THR B OG1 1 ATOM 5791 C CG2 . THR B 1 359 ? 42.587 -56.105 -55.969 1.00 92.84 ? 359 THR B CG2 1 ATOM 5792 N N . GLU B 1 360 ? 45.414 -56.113 -53.638 1.00 98.57 ? 360 GLU B N 1 ATOM 5793 C CA . GLU B 1 360 ? 46.616 -55.271 -53.548 1.00 98.78 ? 360 GLU B CA 1 ATOM 5794 C C . GLU B 1 360 ? 47.075 -55.268 -52.080 1.00 103.27 ? 360 GLU B C 1 ATOM 5795 O O . GLU B 1 360 ? 46.230 -55.165 -51.185 1.00 103.85 ? 360 GLU B O 1 ATOM 5796 C CB . GLU B 1 360 ? 46.303 -53.820 -53.975 1.00 100.21 ? 360 GLU B CB 1 ATOM 5797 C CG . GLU B 1 360 ? 45.883 -53.640 -55.423 1.00 111.28 ? 360 GLU B CG 1 ATOM 5798 C CD . GLU B 1 360 ? 44.845 -52.554 -55.636 1.00 134.97 ? 360 GLU B CD 1 ATOM 5799 O OE1 . GLU B 1 360 ? 45.106 -51.395 -55.236 1.00 132.35 ? 360 GLU B OE1 1 ATOM 5800 O OE2 . GLU B 1 360 ? 43.763 -52.866 -56.186 1.00 121.07 ? 360 GLU B OE2 1 ATOM 5801 N N . LYS B 1 361 ? 48.394 -55.364 -51.829 1.00 99.30 ? 361 LYS B N 1 ATOM 5802 C CA . LYS B 1 361 ? 48.979 -55.344 -50.479 1.00 99.08 ? 361 LYS B CA 1 ATOM 5803 C C . LYS B 1 361 ? 48.637 -54.036 -49.744 1.00 101.86 ? 361 LYS B C 1 ATOM 5804 O O . LYS B 1 361 ? 48.352 -54.050 -48.541 1.00 100.44 ? 361 LYS B O 1 ATOM 5805 C CB . LYS B 1 361 ? 50.512 -55.517 -50.552 1.00 101.99 ? 361 LYS B CB 1 ATOM 5806 C CG . LYS B 1 361 ? 51.032 -56.938 -50.275 1.00 116.18 ? 361 LYS B CG 1 ATOM 5807 C CD . LYS B 1 361 ? 51.104 -57.830 -51.526 1.00 123.89 ? 361 LYS B CD 1 ATOM 5808 C CE . LYS B 1 361 ? 52.345 -57.642 -52.381 1.00 131.96 ? 361 LYS B CE 1 ATOM 5809 N NZ . LYS B 1 361 ? 52.390 -58.595 -53.522 1.00 135.86 ? 361 LYS B NZ 1 ATOM 5810 N N . ASP B 1 362 ? 48.650 -52.919 -50.496 1.00 98.52 ? 362 ASP B N 1 ATOM 5811 C CA . ASP B 1 362 ? 48.348 -51.564 -50.028 1.00 98.47 ? 362 ASP B CA 1 ATOM 5812 C C . ASP B 1 362 ? 46.935 -51.434 -49.431 1.00 99.67 ? 362 ASP B C 1 ATOM 5813 O O . ASP B 1 362 ? 46.766 -50.785 -48.399 1.00 98.86 ? 362 ASP B O 1 ATOM 5814 C CB . ASP B 1 362 ? 48.537 -50.547 -51.183 1.00 100.99 ? 362 ASP B CB 1 ATOM 5815 C CG . ASP B 1 362 ? 49.964 -50.394 -51.706 1.00 114.57 ? 362 ASP B CG 1 ATOM 5816 O OD1 . ASP B 1 362 ? 50.842 -51.196 -51.299 1.00 115.38 ? 362 ASP B OD1 1 ATOM 5817 O OD2 . ASP B 1 362 ? 50.201 -49.478 -52.526 1.00 119.67 ? 362 ASP B OD2 1 ATOM 5818 N N . SER B 1 363 ? 45.933 -52.046 -50.093 1.00 94.19 ? 363 SER B N 1 ATOM 5819 C CA . SER B 1 363 ? 44.525 -52.018 -49.706 1.00 92.62 ? 363 SER B CA 1 ATOM 5820 C C . SER B 1 363 ? 44.186 -53.035 -48.590 1.00 92.10 ? 363 SER B C 1 ATOM 5821 O O . SER B 1 363 ? 44.193 -54.247 -48.850 1.00 91.68 ? 363 SER B O 1 ATOM 5822 C CB . SER B 1 363 ? 43.634 -52.218 -50.933 1.00 97.09 ? 363 SER B CB 1 ATOM 5823 O OG . SER B 1 363 ? 42.249 -52.269 -50.631 1.00 111.74 ? 363 SER B OG 1 ATOM 5824 N N . PRO B 1 364 ? 43.835 -52.556 -47.360 1.00 84.31 ? 364 PRO B N 1 ATOM 5825 C CA . PRO B 1 364 ? 43.439 -53.482 -46.288 1.00 82.70 ? 364 PRO B CA 1 ATOM 5826 C C . PRO B 1 364 ? 42.107 -54.168 -46.596 1.00 82.75 ? 364 PRO B C 1 ATOM 5827 O O . PRO B 1 364 ? 41.392 -53.780 -47.532 1.00 83.62 ? 364 PRO B O 1 ATOM 5828 C CB . PRO B 1 364 ? 43.341 -52.580 -45.044 1.00 84.56 ? 364 PRO B CB 1 ATOM 5829 C CG . PRO B 1 364 ? 43.969 -51.306 -45.416 1.00 89.26 ? 364 PRO B CG 1 ATOM 5830 C CD . PRO B 1 364 ? 43.762 -51.167 -46.891 1.00 85.21 ? 364 PRO B CD 1 ATOM 5831 N N . VAL B 1 365 ? 41.791 -55.204 -45.829 1.00 75.39 ? 365 VAL B N 1 ATOM 5832 C CA . VAL B 1 365 ? 40.598 -56.015 -46.025 1.00 74.72 ? 365 VAL B CA 1 ATOM 5833 C C . VAL B 1 365 ? 39.742 -56.052 -44.776 1.00 76.88 ? 365 VAL B C 1 ATOM 5834 O O . VAL B 1 365 ? 40.266 -56.045 -43.660 1.00 76.59 ? 365 VAL B O 1 ATOM 5835 C CB . VAL B 1 365 ? 40.974 -57.440 -46.514 1.00 79.39 ? 365 VAL B CB 1 ATOM 5836 C CG1 . VAL B 1 365 ? 39.759 -58.366 -46.575 1.00 79.35 ? 365 VAL B CG1 1 ATOM 5837 C CG2 . VAL B 1 365 ? 41.689 -57.397 -47.867 1.00 79.19 ? 365 VAL B CG2 1 ATOM 5838 N N . ASN B 1 366 ? 38.418 -56.127 -44.981 1.00 72.06 ? 366 ASN B N 1 ATOM 5839 C CA . ASN B 1 366 ? 37.417 -56.203 -43.934 1.00 71.41 ? 366 ASN B CA 1 ATOM 5840 C C . ASN B 1 366 ? 36.774 -57.565 -43.908 1.00 75.26 ? 366 ASN B C 1 ATOM 5841 O O . ASN B 1 366 ? 36.252 -58.030 -44.935 1.00 73.86 ? 366 ASN B O 1 ATOM 5842 C CB . ASN B 1 366 ? 36.368 -55.140 -44.129 1.00 69.92 ? 366 ASN B CB 1 ATOM 5843 C CG . ASN B 1 366 ? 36.900 -53.783 -43.825 1.00 107.25 ? 366 ASN B CG 1 ATOM 5844 O OD1 . ASN B 1 366 ? 37.044 -53.380 -42.665 1.00 106.95 ? 366 ASN B OD1 1 ATOM 5845 N ND2 . ASN B 1 366 ? 37.225 -53.061 -44.866 1.00 103.19 ? 366 ASN B ND2 1 ATOM 5846 N N . ILE B 1 367 ? 36.818 -58.222 -42.728 1.00 72.25 ? 367 ILE B N 1 ATOM 5847 C CA . ILE B 1 367 ? 36.217 -59.536 -42.593 1.00 72.73 ? 367 ILE B CA 1 ATOM 5848 C C . ILE B 1 367 ? 35.187 -59.536 -41.476 1.00 75.21 ? 367 ILE B C 1 ATOM 5849 O O . ILE B 1 367 ? 35.472 -59.090 -40.362 1.00 71.60 ? 367 ILE B O 1 ATOM 5850 C CB . ILE B 1 367 ? 37.275 -60.669 -42.425 1.00 76.63 ? 367 ILE B CB 1 ATOM 5851 C CG1 . ILE B 1 367 ? 38.350 -60.661 -43.533 1.00 76.65 ? 367 ILE B CG1 1 ATOM 5852 C CG2 . ILE B 1 367 ? 36.604 -62.039 -42.376 1.00 78.71 ? 367 ILE B CG2 1 ATOM 5853 C CD1 . ILE B 1 367 ? 39.650 -60.338 -43.039 1.00 80.50 ? 367 ILE B CD1 1 ATOM 5854 N N . GLU B 1 368 ? 33.987 -60.039 -41.796 1.00 74.44 ? 368 GLU B N 1 ATOM 5855 C CA . GLU B 1 368 ? 32.904 -60.193 -40.844 1.00 75.40 ? 368 GLU B CA 1 ATOM 5856 C C . GLU B 1 368 ? 32.691 -61.671 -40.643 1.00 80.62 ? 368 GLU B C 1 ATOM 5857 O O . GLU B 1 368 ? 32.511 -62.413 -41.625 1.00 78.44 ? 368 GLU B O 1 ATOM 5858 C CB . GLU B 1 368 ? 31.590 -59.519 -41.306 1.00 77.06 ? 368 GLU B CB 1 ATOM 5859 C CG . GLU B 1 368 ? 30.513 -59.500 -40.215 1.00 88.62 ? 368 GLU B CG 1 ATOM 5860 C CD . GLU B 1 368 ? 29.143 -58.938 -40.552 1.00 94.06 ? 368 GLU B CD 1 ATOM 5861 O OE1 . GLU B 1 368 ? 28.651 -59.174 -41.679 1.00 92.92 ? 368 GLU B OE1 1 ATOM 5862 O OE2 . GLU B 1 368 ? 28.544 -58.287 -39.665 1.00 70.62 ? 368 GLU B OE2 1 ATOM 5863 N N . ALA B 1 369 ? 32.691 -62.083 -39.353 1.00 79.74 ? 369 ALA B N 1 ATOM 5864 C CA . ALA B 1 369 ? 32.475 -63.465 -38.945 1.00 80.68 ? 369 ALA B CA 1 ATOM 5865 C C . ALA B 1 369 ? 31.628 -63.544 -37.702 1.00 86.33 ? 369 ALA B C 1 ATOM 5866 O O . ALA B 1 369 ? 31.637 -62.605 -36.900 1.00 85.13 ? 369 ALA B O 1 ATOM 5867 C CB . ALA B 1 369 ? 33.808 -64.143 -38.696 1.00 81.37 ? 369 ALA B CB 1 ATOM 5868 N N . GLU B 1 370 ? 30.911 -64.681 -37.541 1.00 84.67 ? 370 GLU B N 1 ATOM 5869 C CA . GLU B 1 370 ? 30.090 -64.975 -36.371 1.00 85.49 ? 370 GLU B CA 1 ATOM 5870 C C . GLU B 1 370 ? 30.901 -65.839 -35.382 1.00 91.43 ? 370 GLU B C 1 ATOM 5871 O O . GLU B 1 370 ? 31.054 -67.039 -35.624 1.00 90.26 ? 370 GLU B O 1 ATOM 5872 C CB . GLU B 1 370 ? 28.784 -65.681 -36.772 1.00 86.98 ? 370 GLU B CB 1 ATOM 5873 C CG . GLU B 1 370 ? 27.801 -65.854 -35.616 1.00 98.34 ? 370 GLU B CG 1 ATOM 5874 C CD . GLU B 1 370 ? 26.327 -65.737 -35.972 1.00 122.05 ? 370 GLU B CD 1 ATOM 5875 O OE1 . GLU B 1 370 ? 25.928 -66.292 -37.020 1.00 104.50 ? 370 GLU B OE1 1 ATOM 5876 O OE2 . GLU B 1 370 ? 25.569 -65.099 -35.203 1.00 124.78 ? 370 GLU B OE2 1 ATOM 5877 N N . PRO B 1 371 ? 31.414 -65.263 -34.262 1.00 90.61 ? 371 PRO B N 1 ATOM 5878 C CA . PRO B 1 371 ? 32.163 -66.080 -33.299 1.00 91.56 ? 371 PRO B CA 1 ATOM 5879 C C . PRO B 1 371 ? 31.250 -67.009 -32.511 1.00 100.45 ? 371 PRO B C 1 ATOM 5880 O O . PRO B 1 371 ? 30.062 -66.703 -32.392 1.00 100.76 ? 371 PRO B O 1 ATOM 5881 C CB . PRO B 1 371 ? 32.807 -65.047 -32.377 1.00 92.85 ? 371 PRO B CB 1 ATOM 5882 C CG . PRO B 1 371 ? 31.935 -63.887 -32.432 1.00 97.05 ? 371 PRO B CG 1 ATOM 5883 C CD . PRO B 1 371 ? 31.326 -63.861 -33.809 1.00 92.64 ? 371 PRO B CD 1 ATOM 5884 N N . PRO B 1 372 ? 31.758 -68.136 -31.954 1.00 100.27 ? 372 PRO B N 1 ATOM 5885 C CA . PRO B 1 372 ? 30.874 -69.014 -31.177 1.00 100.65 ? 372 PRO B CA 1 ATOM 5886 C C . PRO B 1 372 ? 30.610 -68.444 -29.783 1.00 104.87 ? 372 PRO B C 1 ATOM 5887 O O . PRO B 1 372 ? 31.366 -67.574 -29.297 1.00 103.66 ? 372 PRO B O 1 ATOM 5888 C CB . PRO B 1 372 ? 31.667 -70.321 -31.116 1.00 102.29 ? 372 PRO B CB 1 ATOM 5889 C CG . PRO B 1 372 ? 33.077 -69.887 -31.122 1.00 106.50 ? 372 PRO B CG 1 ATOM 5890 C CD . PRO B 1 372 ? 33.140 -68.667 -31.985 1.00 102.20 ? 372 PRO B CD 1 ATOM 5891 N N . PHE B 1 373 ? 29.546 -68.961 -29.133 1.00 101.75 ? 373 PHE B N 1 ATOM 5892 C CA . PHE B 1 373 ? 29.210 -68.565 -27.773 1.00 101.57 ? 373 PHE B CA 1 ATOM 5893 C C . PHE B 1 373 ? 30.311 -69.014 -26.822 1.00 107.04 ? 373 PHE B C 1 ATOM 5894 O O . PHE B 1 373 ? 30.634 -70.208 -26.746 1.00 107.01 ? 373 PHE B O 1 ATOM 5895 C CB . PHE B 1 373 ? 27.857 -69.127 -27.328 1.00 102.73 ? 373 PHE B CB 1 ATOM 5896 C CG . PHE B 1 373 ? 26.700 -68.277 -27.764 1.00 103.15 ? 373 PHE B CG 1 ATOM 5897 C CD1 . PHE B 1 373 ? 26.417 -67.076 -27.123 1.00 105.11 ? 373 PHE B CD1 1 ATOM 5898 C CD2 . PHE B 1 373 ? 25.897 -68.669 -28.824 1.00 104.32 ? 373 PHE B CD2 1 ATOM 5899 C CE1 . PHE B 1 373 ? 25.359 -66.274 -27.548 1.00 105.54 ? 373 PHE B CE1 1 ATOM 5900 C CE2 . PHE B 1 373 ? 24.818 -67.886 -29.227 1.00 106.53 ? 373 PHE B CE2 1 ATOM 5901 C CZ . PHE B 1 373 ? 24.559 -66.691 -28.591 1.00 104.48 ? 373 PHE B CZ 1 ATOM 5902 N N . GLY B 1 374 ? 30.921 -68.031 -26.178 1.00 103.74 ? 374 GLY B N 1 ATOM 5903 C CA . GLY B 1 374 ? 32.001 -68.227 -25.232 1.00 103.64 ? 374 GLY B CA 1 ATOM 5904 C C . GLY B 1 374 ? 33.350 -67.906 -25.819 1.00 108.49 ? 374 GLY B C 1 ATOM 5905 O O . GLY B 1 374 ? 33.469 -67.079 -26.737 1.00 107.54 ? 374 GLY B O 1 ATOM 5906 N N . ASP B 1 375 ? 34.377 -68.576 -25.274 1.00 106.26 ? 375 ASP B N 1 ATOM 5907 C CA . ASP B 1 375 ? 35.755 -68.366 -25.671 1.00 106.28 ? 375 ASP B CA 1 ATOM 5908 C C . ASP B 1 375 ? 36.094 -69.077 -26.949 1.00 108.46 ? 375 ASP B C 1 ATOM 5909 O O . ASP B 1 375 ? 35.690 -70.217 -27.211 1.00 106.38 ? 375 ASP B O 1 ATOM 5910 C CB . ASP B 1 375 ? 36.748 -68.661 -24.554 1.00 108.90 ? 375 ASP B CB 1 ATOM 5911 C CG . ASP B 1 375 ? 36.755 -67.597 -23.467 1.00 124.89 ? 375 ASP B CG 1 ATOM 5912 O OD1 . ASP B 1 375 ? 37.068 -66.415 -23.783 1.00 126.38 ? 375 ASP B OD1 1 ATOM 5913 O OD2 . ASP B 1 375 ? 36.409 -67.929 -22.314 1.00 132.35 ? 375 ASP B OD2 1 ATOM 5914 N N . SER B 1 376 ? 36.809 -68.314 -27.774 1.00 105.74 ? 376 SER B N 1 ATOM 5915 C CA . SER B 1 376 ? 37.201 -68.619 -29.135 1.00 105.15 ? 376 SER B CA 1 ATOM 5916 C C . SER B 1 376 ? 38.550 -68.003 -29.498 1.00 108.23 ? 376 SER B C 1 ATOM 5917 O O . SER B 1 376 ? 39.044 -67.083 -28.841 1.00 107.21 ? 376 SER B O 1 ATOM 5918 C CB . SER B 1 376 ? 36.127 -68.106 -30.096 1.00 108.37 ? 376 SER B CB 1 ATOM 5919 O OG . SER B 1 376 ? 35.414 -66.970 -29.620 1.00 114.59 ? 376 SER B OG 1 ATOM 5920 N N . TYR B 1 377 ? 39.126 -68.516 -30.572 1.00 105.71 ? 377 TYR B N 1 ATOM 5921 C CA . TYR B 1 377 ? 40.380 -68.049 -31.118 1.00 106.38 ? 377 TYR B CA 1 ATOM 5922 C C . TYR B 1 377 ? 40.139 -67.640 -32.584 1.00 105.60 ? 377 TYR B C 1 ATOM 5923 O O . TYR B 1 377 ? 39.673 -68.451 -33.396 1.00 103.22 ? 377 TYR B O 1 ATOM 5924 C CB . TYR B 1 377 ? 41.456 -69.162 -31.003 1.00 110.46 ? 377 TYR B CB 1 ATOM 5925 C CG . TYR B 1 377 ? 42.492 -68.998 -29.901 1.00 115.98 ? 377 TYR B CG 1 ATOM 5926 C CD1 . TYR B 1 377 ? 42.920 -67.733 -29.497 1.00 119.21 ? 377 TYR B CD1 1 ATOM 5927 C CD2 . TYR B 1 377 ? 43.117 -70.107 -29.330 1.00 117.40 ? 377 TYR B CD2 1 ATOM 5928 C CE1 . TYR B 1 377 ? 43.891 -67.575 -28.503 1.00 121.62 ? 377 TYR B CE1 1 ATOM 5929 C CE2 . TYR B 1 377 ? 44.091 -69.962 -28.336 1.00 118.93 ? 377 TYR B CE2 1 ATOM 5930 C CZ . TYR B 1 377 ? 44.479 -68.690 -27.928 1.00 129.38 ? 377 TYR B CZ 1 ATOM 5931 O OH . TYR B 1 377 ? 45.446 -68.507 -26.961 1.00 130.88 ? 377 TYR B OH 1 ATOM 5932 N N . ILE B 1 378 ? 40.370 -66.359 -32.893 1.00 100.95 ? 378 ILE B N 1 ATOM 5933 C CA . ILE B 1 378 ? 40.242 -65.858 -34.253 1.00 100.37 ? 378 ILE B CA 1 ATOM 5934 C C . ILE B 1 378 ? 41.622 -65.881 -34.843 1.00 101.08 ? 378 ILE B C 1 ATOM 5935 O O . ILE B 1 378 ? 42.495 -65.111 -34.435 1.00 99.86 ? 378 ILE B O 1 ATOM 5936 C CB . ILE B 1 378 ? 39.530 -64.484 -34.383 1.00 103.89 ? 378 ILE B CB 1 ATOM 5937 C CG1 . ILE B 1 378 ? 38.049 -64.631 -34.006 1.00 104.21 ? 378 ILE B CG1 1 ATOM 5938 C CG2 . ILE B 1 378 ? 39.668 -63.919 -35.824 1.00 105.24 ? 378 ILE B CG2 1 ATOM 5939 C CD1 . ILE B 1 378 ? 37.521 -63.495 -33.256 1.00 109.68 ? 378 ILE B CD1 1 ATOM 5940 N N . ILE B 1 379 ? 41.824 -66.823 -35.761 1.00 95.85 ? 379 ILE B N 1 ATOM 5941 C CA . ILE B 1 379 ? 43.091 -67.021 -36.415 1.00 94.94 ? 379 ILE B CA 1 ATOM 5942 C C . ILE B 1 379 ? 42.983 -66.609 -37.866 1.00 98.25 ? 379 ILE B C 1 ATOM 5943 O O . ILE B 1 379 ? 42.215 -67.179 -38.660 1.00 96.47 ? 379 ILE B O 1 ATOM 5944 C CB . ILE B 1 379 ? 43.644 -68.446 -36.160 1.00 97.69 ? 379 ILE B CB 1 ATOM 5945 C CG1 . ILE B 1 379 ? 44.369 -68.485 -34.814 1.00 97.91 ? 379 ILE B CG1 1 ATOM 5946 C CG2 . ILE B 1 379 ? 44.579 -68.921 -37.257 1.00 97.95 ? 379 ILE B CG2 1 ATOM 5947 C CD1 . ILE B 1 379 ? 43.544 -68.919 -33.665 1.00 102.65 ? 379 ILE B CD1 1 ATOM 5948 N N . VAL B 1 380 ? 43.727 -65.545 -38.172 1.00 95.71 ? 380 VAL B N 1 ATOM 5949 C CA . VAL B 1 380 ? 43.826 -64.955 -39.498 1.00 95.89 ? 380 VAL B CA 1 ATOM 5950 C C . VAL B 1 380 ? 45.261 -65.042 -39.970 1.00 101.19 ? 380 VAL B C 1 ATOM 5951 O O . VAL B 1 380 ? 46.188 -64.575 -39.296 1.00 100.81 ? 380 VAL B O 1 ATOM 5952 C CB . VAL B 1 380 ? 43.193 -63.530 -39.637 1.00 98.95 ? 380 VAL B CB 1 ATOM 5953 C CG1 . VAL B 1 380 ? 43.650 -62.578 -38.533 1.00 98.67 ? 380 VAL B CG1 1 ATOM 5954 C CG2 . VAL B 1 380 ? 43.415 -62.932 -41.028 1.00 98.29 ? 380 VAL B CG2 1 ATOM 5955 N N . GLY B 1 381 ? 45.413 -65.686 -41.117 1.00 98.30 ? 381 GLY B N 1 ATOM 5956 C CA . GLY B 1 381 ? 46.702 -65.888 -41.740 1.00 98.34 ? 381 GLY B CA 1 ATOM 5957 C C . GLY B 1 381 ? 47.261 -67.250 -41.441 1.00 103.34 ? 381 GLY B C 1 ATOM 5958 O O . GLY B 1 381 ? 46.580 -68.112 -40.868 1.00 102.96 ? 381 GLY B O 1 ATOM 5959 N N . VAL B 1 382 ? 48.511 -67.431 -41.844 1.00 100.10 ? 382 VAL B N 1 ATOM 5960 C CA . VAL B 1 382 ? 49.255 -68.672 -41.674 1.00 99.71 ? 382 VAL B CA 1 ATOM 5961 C C . VAL B 1 382 ? 50.603 -68.363 -40.987 1.00 104.97 ? 382 VAL B C 1 ATOM 5962 O O . VAL B 1 382 ? 51.101 -67.231 -41.091 1.00 105.33 ? 382 VAL B O 1 ATOM 5963 C CB . VAL B 1 382 ? 49.411 -69.446 -43.013 1.00 102.72 ? 382 VAL B CB 1 ATOM 5964 C CG1 . VAL B 1 382 ? 48.162 -70.240 -43.363 1.00 102.17 ? 382 VAL B CG1 1 ATOM 5965 C CG2 . VAL B 1 382 ? 49.837 -68.528 -44.161 1.00 102.54 ? 382 VAL B CG2 1 ATOM 5966 N N . GLU B 1 383 ? 51.162 -69.359 -40.258 1.00 100.05 ? 383 GLU B N 1 ATOM 5967 C CA . GLU B 1 383 ? 52.426 -69.260 -39.519 1.00 98.29 ? 383 GLU B CA 1 ATOM 5968 C C . GLU B 1 383 ? 53.627 -69.230 -40.489 1.00 99.58 ? 383 GLU B C 1 ATOM 5969 O O . GLU B 1 383 ? 53.551 -69.897 -41.522 1.00 98.19 ? 383 GLU B O 1 ATOM 5970 C CB . GLU B 1 383 ? 52.522 -70.350 -38.444 1.00 99.36 ? 383 GLU B CB 1 ATOM 5971 C CG . GLU B 1 383 ? 52.375 -71.761 -38.989 1.00 107.51 ? 383 GLU B CG 1 ATOM 5972 C CD . GLU B 1 383 ? 50.987 -72.371 -38.991 1.00 112.57 ? 383 GLU B CD 1 ATOM 5973 O OE1 . GLU B 1 383 ? 50.089 -71.815 -39.664 1.00 89.53 ? 383 GLU B OE1 1 ATOM 5974 O OE2 . GLU B 1 383 ? 50.817 -73.447 -38.372 1.00 106.38 ? 383 GLU B OE2 1 ATOM 5975 N N . PRO B 1 384 ? 54.690 -68.410 -40.255 1.00 96.31 ? 384 PRO B N 1 ATOM 5976 C CA . PRO B 1 384 ? 54.934 -67.543 -39.086 1.00 96.61 ? 384 PRO B CA 1 ATOM 5977 C C . PRO B 1 384 ? 54.084 -66.292 -39.158 1.00 103.70 ? 384 PRO B C 1 ATOM 5978 O O . PRO B 1 384 ? 53.550 -65.967 -40.232 1.00 104.66 ? 384 PRO B O 1 ATOM 5979 C CB . PRO B 1 384 ? 56.426 -67.201 -39.214 1.00 97.80 ? 384 PRO B CB 1 ATOM 5980 C CG . PRO B 1 384 ? 56.656 -67.179 -40.698 1.00 101.67 ? 384 PRO B CG 1 ATOM 5981 C CD . PRO B 1 384 ? 55.804 -68.310 -41.224 1.00 97.36 ? 384 PRO B CD 1 ATOM 5982 N N . GLY B 1 385 ? 53.946 -65.624 -38.016 1.00 99.93 ? 385 GLY B N 1 ATOM 5983 C CA . GLY B 1 385 ? 53.146 -64.409 -37.909 1.00 99.09 ? 385 GLY B CA 1 ATOM 5984 C C . GLY B 1 385 ? 51.655 -64.651 -38.050 1.00 100.08 ? 385 GLY B C 1 ATOM 5985 O O . GLY B 1 385 ? 50.913 -63.740 -38.447 1.00 99.69 ? 385 GLY B O 1 ATOM 5986 N N . GLN B 1 386 ? 51.210 -65.897 -37.737 1.00 93.85 ? 386 GLN B N 1 ATOM 5987 C CA . GLN B 1 386 ? 49.801 -66.260 -37.745 1.00 92.36 ? 386 GLN B CA 1 ATOM 5988 C C . GLN B 1 386 ? 49.127 -65.429 -36.627 1.00 98.12 ? 386 GLN B C 1 ATOM 5989 O O . GLN B 1 386 ? 49.524 -65.535 -35.451 1.00 97.50 ? 386 GLN B O 1 ATOM 5990 C CB . GLN B 1 386 ? 49.605 -67.771 -37.525 1.00 92.25 ? 386 GLN B CB 1 ATOM 5991 C CG . GLN B 1 386 ? 48.146 -68.196 -37.613 1.00 86.28 ? 386 GLN B CG 1 ATOM 5992 C CD . GLN B 1 386 ? 47.917 -69.682 -37.529 1.00 105.87 ? 386 GLN B CD 1 ATOM 5993 O OE1 . GLN B 1 386 ? 48.088 -70.318 -36.485 1.00 99.35 ? 386 GLN B OE1 1 ATOM 5994 N NE2 . GLN B 1 386 ? 47.419 -70.258 -38.608 1.00 105.48 ? 386 GLN B NE2 1 ATOM 5995 N N . LEU B 1 387 ? 48.181 -64.528 -37.017 1.00 95.11 ? 387 LEU B N 1 ATOM 5996 C CA . LEU B 1 387 ? 47.474 -63.723 -36.030 1.00 95.35 ? 387 LEU B CA 1 ATOM 5997 C C . LEU B 1 387 ? 46.522 -64.631 -35.264 1.00 101.14 ? 387 LEU B C 1 ATOM 5998 O O . LEU B 1 387 ? 45.713 -65.337 -35.878 1.00 100.68 ? 387 LEU B O 1 ATOM 5999 C CB . LEU B 1 387 ? 46.734 -62.536 -36.660 1.00 95.46 ? 387 LEU B CB 1 ATOM 6000 C CG . LEU B 1 387 ? 47.588 -61.419 -37.288 1.00 100.19 ? 387 LEU B CG 1 ATOM 6001 C CD1 . LEU B 1 387 ? 46.719 -60.417 -38.021 1.00 100.07 ? 387 LEU B CD1 1 ATOM 6002 C CD2 . LEU B 1 387 ? 48.397 -60.671 -36.246 1.00 101.63 ? 387 LEU B CD2 1 ATOM 6003 N N . LYS B 1 388 ? 46.709 -64.702 -33.931 1.00 98.92 ? 388 LYS B N 1 ATOM 6004 C CA . LYS B 1 388 ? 45.911 -65.560 -33.064 1.00 99.79 ? 388 LYS B CA 1 ATOM 6005 C C . LYS B 1 388 ? 45.215 -64.705 -32.013 1.00 106.09 ? 388 LYS B C 1 ATOM 6006 O O . LYS B 1 388 ? 45.711 -64.526 -30.897 1.00 106.47 ? 388 LYS B O 1 ATOM 6007 C CB . LYS B 1 388 ? 46.766 -66.687 -32.441 1.00 103.15 ? 388 LYS B CB 1 ATOM 6008 C CG . LYS B 1 388 ? 47.635 -67.452 -33.438 1.00 125.51 ? 388 LYS B CG 1 ATOM 6009 C CD . LYS B 1 388 ? 48.772 -68.200 -32.746 1.00 137.81 ? 388 LYS B CD 1 ATOM 6010 C CE . LYS B 1 388 ? 49.837 -68.698 -33.707 1.00 143.90 ? 388 LYS B CE 1 ATOM 6011 N NZ . LYS B 1 388 ? 50.774 -67.615 -34.119 1.00 148.09 ? 388 LYS B NZ 1 ATOM 6012 N N . LEU B 1 389 ? 44.074 -64.136 -32.404 1.00 103.78 ? 389 LEU B N 1 ATOM 6013 C CA . LEU B 1 389 ? 43.255 -63.264 -31.568 1.00 104.14 ? 389 LEU B CA 1 ATOM 6014 C C . LEU B 1 389 ? 42.288 -64.076 -30.730 1.00 107.30 ? 389 LEU B C 1 ATOM 6015 O O . LEU B 1 389 ? 41.899 -65.166 -31.128 1.00 106.21 ? 389 LEU B O 1 ATOM 6016 C CB . LEU B 1 389 ? 42.519 -62.227 -32.439 1.00 104.55 ? 389 LEU B CB 1 ATOM 6017 C CG . LEU B 1 389 ? 43.434 -61.314 -33.286 1.00 109.84 ? 389 LEU B CG 1 ATOM 6018 C CD1 . LEU B 1 389 ? 42.739 -60.822 -34.550 1.00 110.39 ? 389 LEU B CD1 1 ATOM 6019 C CD2 . LEU B 1 389 ? 44.028 -60.170 -32.455 1.00 112.44 ? 389 LEU B CD2 1 ATOM 6020 N N . ASN B 1 390 ? 41.929 -63.557 -29.557 1.00 103.79 ? 390 ASN B N 1 ATOM 6021 C CA . ASN B 1 390 ? 41.036 -64.224 -28.604 1.00 103.49 ? 390 ASN B CA 1 ATOM 6022 C C . ASN B 1 390 ? 39.747 -63.457 -28.424 1.00 107.12 ? 390 ASN B C 1 ATOM 6023 O O . ASN B 1 390 ? 39.767 -62.235 -28.249 1.00 107.04 ? 390 ASN B O 1 ATOM 6024 C CB . ASN B 1 390 ? 41.727 -64.420 -27.255 1.00 103.15 ? 390 ASN B CB 1 ATOM 6025 C CG . ASN B 1 390 ? 42.765 -63.366 -26.927 1.00 125.65 ? 390 ASN B CG 1 ATOM 6026 O OD1 . ASN B 1 390 ? 42.649 -62.186 -27.279 1.00 123.48 ? 390 ASN B OD1 1 ATOM 6027 N ND2 . ASN B 1 390 ? 43.817 -63.776 -26.254 1.00 116.70 ? 390 ASN B ND2 1 ATOM 6028 N N . TRP B 1 391 ? 38.625 -64.180 -28.442 1.00 103.06 ? 391 TRP B N 1 ATOM 6029 C CA . TRP B 1 391 ? 37.301 -63.576 -28.322 1.00 102.57 ? 391 TRP B CA 1 ATOM 6030 C C . TRP B 1 391 ? 36.379 -64.282 -27.333 1.00 106.58 ? 391 TRP B C 1 ATOM 6031 O O . TRP B 1 391 ? 36.555 -65.468 -27.063 1.00 105.68 ? 391 TRP B O 1 ATOM 6032 C CB . TRP B 1 391 ? 36.622 -63.551 -29.711 1.00 100.91 ? 391 TRP B CB 1 ATOM 6033 C CG . TRP B 1 391 ? 35.476 -62.586 -29.794 1.00 101.28 ? 391 TRP B CG 1 ATOM 6034 C CD1 . TRP B 1 391 ? 34.142 -62.887 -29.831 1.00 103.99 ? 391 TRP B CD1 1 ATOM 6035 C CD2 . TRP B 1 391 ? 35.566 -61.164 -29.690 1.00 100.86 ? 391 TRP B CD2 1 ATOM 6036 N NE1 . TRP B 1 391 ? 33.400 -61.733 -29.825 1.00 103.16 ? 391 TRP B NE1 1 ATOM 6037 C CE2 . TRP B 1 391 ? 34.247 -60.660 -29.697 1.00 104.43 ? 391 TRP B CE2 1 ATOM 6038 C CE3 . TRP B 1 391 ? 36.641 -60.261 -29.574 1.00 101.94 ? 391 TRP B CE3 1 ATOM 6039 C CZ2 . TRP B 1 391 ? 33.971 -59.293 -29.603 1.00 103.58 ? 391 TRP B CZ2 1 ATOM 6040 C CZ3 . TRP B 1 391 ? 36.368 -58.907 -29.490 1.00 103.33 ? 391 TRP B CZ3 1 ATOM 6041 C CH2 . TRP B 1 391 ? 35.047 -58.434 -29.526 1.00 103.99 ? 391 TRP B CH2 1 ATOM 6042 N N . LEU B 1 392 ? 35.340 -63.567 -26.849 1.00 103.39 ? 392 LEU B N 1 ATOM 6043 C CA . LEU B 1 392 ? 34.281 -64.107 -25.995 1.00 103.20 ? 392 LEU B CA 1 ATOM 6044 C C . LEU B 1 392 ? 32.905 -63.523 -26.358 1.00 106.21 ? 392 LEU B C 1 ATOM 6045 O O . LEU B 1 392 ? 32.730 -62.305 -26.329 1.00 105.53 ? 392 LEU B O 1 ATOM 6046 C CB . LEU B 1 392 ? 34.571 -63.946 -24.489 1.00 103.36 ? 392 LEU B CB 1 ATOM 6047 C CG . LEU B 1 392 ? 33.444 -64.447 -23.555 1.00 107.74 ? 392 LEU B CG 1 ATOM 6048 C CD1 . LEU B 1 392 ? 33.809 -65.750 -22.886 1.00 107.85 ? 392 LEU B CD1 1 ATOM 6049 C CD2 . LEU B 1 392 ? 33.018 -63.381 -22.552 1.00 108.63 ? 392 LEU B CD2 1 ATOM 6050 N N . ARG B 1 393 ? 31.932 -64.402 -26.664 1.00 102.67 ? 393 ARG B N 1 ATOM 6051 C CA . ARG B 1 393 ? 30.545 -64.044 -26.967 1.00 102.53 ? 393 ARG B CA 1 ATOM 6052 C C . ARG B 1 393 ? 29.622 -64.674 -25.875 1.00 108.97 ? 393 ARG B C 1 ATOM 6053 O O . ARG B 1 393 ? 29.260 -65.846 -25.983 1.00 107.95 ? 393 ARG B O 1 ATOM 6054 C CB . ARG B 1 393 ? 30.170 -64.491 -28.387 1.00 99.90 ? 393 ARG B CB 1 ATOM 6055 C CG . ARG B 1 393 ? 28.845 -63.917 -28.878 1.00 96.31 ? 393 ARG B CG 1 ATOM 6056 C CD . ARG B 1 393 ? 28.253 -64.800 -29.944 1.00 81.42 ? 393 ARG B CD 1 ATOM 6057 N NE . ARG B 1 393 ? 26.901 -64.391 -30.301 1.00 76.44 ? 393 ARG B NE 1 ATOM 6058 C CZ . ARG B 1 393 ? 26.227 -64.858 -31.351 1.00 94.45 ? 393 ARG B CZ 1 ATOM 6059 N NH1 . ARG B 1 393 ? 26.781 -65.754 -32.164 1.00 77.04 ? 393 ARG B NH1 1 ATOM 6060 N NH2 . ARG B 1 393 ? 24.992 -64.435 -31.596 1.00 84.34 ? 393 ARG B NH2 1 ATOM 6061 N N . PRO B 1 394 ? 29.262 -63.914 -24.806 1.00 108.49 ? 394 PRO B N 1 ATOM 6062 C CA . PRO B 1 394 ? 28.482 -64.497 -23.693 1.00 109.29 ? 394 PRO B CA 1 ATOM 6063 C C . PRO B 1 394 ? 27.066 -64.949 -24.031 1.00 115.34 ? 394 PRO B C 1 ATOM 6064 O O . PRO B 1 394 ? 26.504 -64.505 -25.039 1.00 115.31 ? 394 PRO B O 1 ATOM 6065 C CB . PRO B 1 394 ? 28.486 -63.391 -22.636 1.00 111.06 ? 394 PRO B CB 1 ATOM 6066 C CG . PRO B 1 394 ? 28.719 -62.139 -23.400 1.00 115.28 ? 394 PRO B CG 1 ATOM 6067 C CD . PRO B 1 394 ? 29.643 -62.519 -24.507 1.00 110.56 ? 394 PRO B CD 1 ATOM 6068 N N . LEU B 1 395 ? 26.503 -65.854 -23.185 1.00 112.30 ? 395 LEU B N 1 ATOM 6069 C CA . LEU B 1 395 ? 25.158 -66.406 -23.361 1.00 140.70 ? 395 LEU B CA 1 ATOM 6070 C C . LEU B 1 395 ? 24.096 -65.517 -22.721 1.00 157.38 ? 395 LEU B C 1 ATOM 6071 O O . LEU B 1 395 ? 23.512 -64.669 -23.397 1.00 117.77 ? 395 LEU B O 1 ATOM 6072 C CB . LEU B 1 395 ? 25.082 -67.830 -22.803 1.00 140.75 ? 395 LEU B CB 1 HETATM 6073 C C1 . NAG C 2 . ? -26.154 15.269 -37.798 1.00 136.15 ? 501 NAG A C1 1 HETATM 6074 C C2 . NAG C 2 . ? -26.301 15.777 -39.237 1.00 136.95 ? 501 NAG A C2 1 HETATM 6075 C C3 . NAG C 2 . ? -25.196 16.777 -39.583 1.00 138.90 ? 501 NAG A C3 1 HETATM 6076 C C4 . NAG C 2 . ? -25.140 17.873 -38.527 1.00 140.19 ? 501 NAG A C4 1 HETATM 6077 C C5 . NAG C 2 . ? -24.874 17.222 -37.174 1.00 136.07 ? 501 NAG A C5 1 HETATM 6078 C C6 . NAG C 2 . ? -24.654 18.209 -36.046 1.00 132.06 ? 501 NAG A C6 1 HETATM 6079 C C7 . NAG C 2 . ? -27.470 14.128 -40.652 1.00 132.65 ? 501 NAG A C7 1 HETATM 6080 C C8 . NAG C 2 . ? -27.314 13.170 -41.792 1.00 132.28 ? 501 NAG A C8 1 HETATM 6081 N N2 . NAG C 2 . ? -26.341 14.702 -40.215 1.00 134.43 ? 501 NAG A N2 1 HETATM 6082 O O3 . NAG C 2 . ? -25.404 17.333 -40.877 1.00 139.27 ? 501 NAG A O3 1 HETATM 6083 O O4 . NAG C 2 . ? -24.146 18.838 -38.855 1.00 145.54 ? 501 NAG A O4 1 HETATM 6084 O O5 . NAG C 2 . ? -25.961 16.335 -36.842 1.00 136.48 ? 501 NAG A O5 1 HETATM 6085 O O6 . NAG C 2 . ? -25.636 18.185 -35.024 1.00 129.73 ? 501 NAG A O6 1 HETATM 6086 O O7 . NAG C 2 . ? -28.567 14.387 -40.167 1.00 132.44 ? 501 NAG A O7 1 HETATM 6087 C C1 . FUC D 3 . ? -26.458 19.322 -34.929 1.00 126.93 ? 502 FUC A C1 1 HETATM 6088 C C2 . FUC D 3 . ? -27.042 19.387 -33.502 1.00 125.62 ? 502 FUC A C2 1 HETATM 6089 C C3 . FUC D 3 . ? -27.375 20.808 -33.063 1.00 124.58 ? 502 FUC A C3 1 HETATM 6090 C C4 . FUC D 3 . ? -27.732 21.700 -34.246 1.00 126.14 ? 502 FUC A C4 1 HETATM 6091 C C5 . FUC D 3 . ? -26.538 21.817 -35.198 1.00 125.52 ? 502 FUC A C5 1 HETATM 6092 C C6 . FUC D 3 . ? -26.914 22.275 -36.587 1.00 125.72 ? 502 FUC A C6 1 HETATM 6093 O O2 . FUC D 3 . ? -26.165 18.804 -32.544 1.00 125.34 ? 502 FUC A O2 1 HETATM 6094 O O3 . FUC D 3 . ? -28.435 20.774 -32.114 1.00 123.05 ? 502 FUC A O3 1 HETATM 6095 O O4 . FUC D 3 . ? -28.904 21.236 -34.914 1.00 127.82 ? 502 FUC A O4 1 HETATM 6096 O O5 . FUC D 3 . ? -25.828 20.562 -35.291 1.00 125.02 ? 502 FUC A O5 1 HETATM 6097 C C1 . NAG E 2 . ? -24.566 20.181 -39.041 1.00 149.85 ? 503 NAG A C1 1 HETATM 6098 C C2 . NAG E 2 . ? -23.487 21.108 -38.486 1.00 150.83 ? 503 NAG A C2 1 HETATM 6099 C C3 . NAG E 2 . ? -24.059 22.520 -38.586 1.00 153.85 ? 503 NAG A C3 1 HETATM 6100 C C4 . NAG E 2 . ? -24.408 22.867 -40.032 1.00 155.54 ? 503 NAG A C4 1 HETATM 6101 C C5 . NAG E 2 . ? -25.311 21.800 -40.648 1.00 155.16 ? 503 NAG A C5 1 HETATM 6102 C C6 . NAG E 2 . ? -25.491 21.948 -42.143 1.00 156.49 ? 503 NAG A C6 1 HETATM 6103 C C7 . NAG E 2 . ? -21.896 20.583 -36.681 1.00 146.63 ? 503 NAG A C7 1 HETATM 6104 C C8 . NAG E 2 . ? -21.694 20.633 -35.198 1.00 146.58 ? 503 NAG A C8 1 HETATM 6105 N N2 . NAG E 2 . ? -23.143 20.804 -37.106 1.00 148.67 ? 503 NAG A N2 1 HETATM 6106 O O3 . NAG E 2 . ? -23.111 23.434 -38.050 1.00 154.91 ? 503 NAG A O3 1 HETATM 6107 O O4 . NAG E 2 . ? -25.064 24.131 -40.076 1.00 156.65 ? 503 NAG A O4 1 HETATM 6108 O O5 . NAG E 2 . ? -24.748 20.496 -40.424 1.00 152.71 ? 503 NAG A O5 1 HETATM 6109 O O6 . NAG E 2 . ? -26.372 20.963 -42.673 1.00 156.90 ? 503 NAG A O6 1 HETATM 6110 O O7 . NAG E 2 . ? -20.970 20.362 -37.455 1.00 145.63 ? 503 NAG A O7 1 HETATM 6111 C C1 . NAG F 2 . ? 19.902 -18.634 -35.197 1.00 119.61 ? 567 NAG A C1 1 HETATM 6112 C C2 . NAG F 2 . ? 20.583 -17.918 -34.032 1.00 119.57 ? 567 NAG A C2 1 HETATM 6113 C C3 . NAG F 2 . ? 21.110 -16.559 -34.495 1.00 123.34 ? 567 NAG A C3 1 HETATM 6114 C C4 . NAG F 2 . ? 22.050 -16.718 -35.687 1.00 126.14 ? 567 NAG A C4 1 HETATM 6115 C C5 . NAG F 2 . ? 21.348 -17.475 -36.815 1.00 123.00 ? 567 NAG A C5 1 HETATM 6116 C C6 . NAG F 2 . ? 22.287 -17.868 -37.936 1.00 118.98 ? 567 NAG A C6 1 HETATM 6117 C C7 . NAG F 2 . ? 20.050 -17.750 -31.628 1.00 114.61 ? 567 NAG A C7 1 HETATM 6118 C C8 . NAG F 2 . ? 19.026 -17.283 -30.644 1.00 114.16 ? 567 NAG A C8 1 HETATM 6119 N N2 . NAG F 2 . ? 19.661 -17.764 -32.917 1.00 116.34 ? 567 NAG A N2 1 HETATM 6120 O O3 . NAG F 2 . ? 21.814 -15.940 -33.425 1.00 124.79 ? 567 NAG A O3 1 HETATM 6121 O O4 . NAG F 2 . ? 22.471 -15.425 -36.120 1.00 132.17 ? 567 NAG A O4 1 HETATM 6122 O O5 . NAG F 2 . ? 20.798 -18.707 -36.317 1.00 123.23 ? 567 NAG A O5 1 HETATM 6123 O O6 . NAG F 2 . ? 21.587 -18.424 -39.033 1.00 118.05 ? 567 NAG A O6 1 HETATM 6124 O O7 . NAG F 2 . ? 21.181 -18.077 -31.277 1.00 113.76 ? 567 NAG A O7 1 HETATM 6125 C C1 . NAG G 2 . ? 23.827 -15.220 -36.540 1.00 138.68 ? 569 NAG A C1 1 HETATM 6126 C C2 . NAG G 2 . ? 23.833 -14.193 -37.673 1.00 143.98 ? 569 NAG A C2 1 HETATM 6127 C C3 . NAG G 2 . ? 24.825 -13.080 -37.341 1.00 146.02 ? 569 NAG A C3 1 HETATM 6128 C C4 . NAG G 2 . ? 24.578 -12.563 -35.928 1.00 145.58 ? 569 NAG A C4 1 HETATM 6129 C C5 . NAG G 2 . ? 24.834 -13.652 -34.886 1.00 144.49 ? 569 NAG A C5 1 HETATM 6130 C C6 . NAG G 2 . ? 23.899 -13.580 -33.696 1.00 146.14 ? 569 NAG A C6 1 HETATM 6131 C C7 . NAG G 2 . ? 23.291 -15.025 -39.940 1.00 147.77 ? 569 NAG A C7 1 HETATM 6132 C C8 . NAG G 2 . ? 23.825 -15.737 -41.148 1.00 148.19 ? 569 NAG A C8 1 HETATM 6133 N N2 . NAG G 2 . ? 24.172 -14.823 -38.940 1.00 146.93 ? 569 NAG A N2 1 HETATM 6134 O O3 . NAG G 2 . ? 24.683 -12.014 -38.275 1.00 147.27 ? 569 NAG A O3 1 HETATM 6135 O O4 . NAG G 2 . ? 25.403 -11.430 -35.665 1.00 145.07 ? 569 NAG A O4 1 HETATM 6136 O O5 . NAG G 2 . ? 24.738 -14.978 -35.451 1.00 141.02 ? 569 NAG A O5 1 HETATM 6137 O O6 . NAG G 2 . ? 24.136 -14.629 -32.764 1.00 146.65 ? 569 NAG A O6 1 HETATM 6138 O O7 . NAG G 2 . ? 22.121 -14.656 -39.870 1.00 147.22 ? 569 NAG A O7 1 HETATM 6139 C C1 . NAG H 2 . ? 32.722 -44.524 -48.151 1.00 81.59 ? 501 NAG B C1 1 HETATM 6140 C C2 . NAG H 2 . ? 33.787 -44.090 -47.140 1.00 82.21 ? 501 NAG B C2 1 HETATM 6141 C C3 . NAG H 2 . ? 34.550 -42.878 -47.671 1.00 80.42 ? 501 NAG B C3 1 HETATM 6142 C C4 . NAG H 2 . ? 35.116 -43.185 -49.051 1.00 80.88 ? 501 NAG B C4 1 HETATM 6143 C C5 . NAG H 2 . ? 33.949 -43.543 -49.968 1.00 80.40 ? 501 NAG B C5 1 HETATM 6144 C C6 . NAG H 2 . ? 34.323 -43.727 -51.424 1.00 76.83 ? 501 NAG B C6 1 HETATM 6145 C C7 . NAG H 2 . ? 33.132 -44.666 -44.838 1.00 88.79 ? 501 NAG B C7 1 HETATM 6146 C C8 . NAG H 2 . ? 32.580 -44.130 -43.553 1.00 87.87 ? 501 NAG B C8 1 HETATM 6147 N N2 . NAG H 2 . ? 33.191 -43.791 -45.851 1.00 86.39 ? 501 NAG B N2 1 HETATM 6148 O O3 . NAG H 2 . ? 35.574 -42.464 -46.771 1.00 80.11 ? 501 NAG B O3 1 HETATM 6149 O O4 . NAG H 2 . ? 35.834 -42.064 -49.552 1.00 82.85 ? 501 NAG B O4 1 HETATM 6150 O O5 . NAG H 2 . ? 33.286 -44.724 -49.470 1.00 82.01 ? 501 NAG B O5 1 HETATM 6151 O O6 . NAG H 2 . ? 34.162 -45.038 -51.923 1.00 75.89 ? 501 NAG B O6 1 HETATM 6152 O O7 . NAG H 2 . ? 33.488 -45.838 -44.958 1.00 90.59 ? 501 NAG B O7 1 HETATM 6153 C C1 . FUC I 3 . ? 35.350 -45.728 -52.227 1.00 73.27 ? 502 FUC B C1 1 HETATM 6154 C C2 . FUC I 3 . ? 35.026 -46.841 -53.251 1.00 70.49 ? 502 FUC B C2 1 HETATM 6155 C C3 . FUC I 3 . ? 36.212 -47.159 -54.148 1.00 67.29 ? 502 FUC B C3 1 HETATM 6156 C C4 . FUC I 3 . ? 37.539 -46.949 -53.418 1.00 69.48 ? 502 FUC B C4 1 HETATM 6157 C C5 . FUC I 3 . ? 37.705 -45.467 -53.077 1.00 69.14 ? 502 FUC B C5 1 HETATM 6158 C C6 . FUC I 3 . ? 38.742 -45.194 -52.010 1.00 61.99 ? 502 FUC B C6 1 HETATM 6159 O O2 . FUC I 3 . ? 33.872 -46.576 -54.037 1.00 72.26 ? 502 FUC B O2 1 HETATM 6160 O O3 . FUC I 3 . ? 36.086 -48.499 -54.602 1.00 66.65 ? 502 FUC B O3 1 HETATM 6161 O O4 . FUC I 3 . ? 37.645 -47.771 -52.258 1.00 69.82 ? 502 FUC B O4 1 HETATM 6162 O O5 . FUC I 3 . ? 36.438 -44.899 -52.671 1.00 72.54 ? 502 FUC B O5 1 HETATM 6163 C C1 . NAG J 2 . ? 37.200 -42.234 -49.865 1.00 83.86 ? 503 NAG B C1 1 HETATM 6164 C C2 . NAG J 2 . ? 37.508 -41.393 -51.101 1.00 86.10 ? 503 NAG B C2 1 HETATM 6165 C C3 . NAG J 2 . ? 38.949 -41.726 -51.466 1.00 87.81 ? 503 NAG B C3 1 HETATM 6166 C C4 . NAG J 2 . ? 39.905 -41.342 -50.334 1.00 87.86 ? 503 NAG B C4 1 HETATM 6167 C C5 . NAG J 2 . ? 39.447 -41.946 -49.005 1.00 86.94 ? 503 NAG B C5 1 HETATM 6168 C C6 . NAG J 2 . ? 40.137 -41.322 -47.813 1.00 87.86 ? 503 NAG B C6 1 HETATM 6169 C C7 . NAG J 2 . ? 35.949 -40.764 -52.903 1.00 86.11 ? 503 NAG B C7 1 HETATM 6170 C C8 . NAG J 2 . ? 35.395 -41.210 -54.223 1.00 86.25 ? 503 NAG B C8 1 HETATM 6171 N N2 . NAG J 2 . ? 36.631 -41.691 -52.219 1.00 87.83 ? 503 NAG B N2 1 HETATM 6172 O O3 . NAG J 2 . ? 39.257 -41.016 -52.660 1.00 88.31 ? 503 NAG B O3 1 HETATM 6173 O O4 . NAG J 2 . ? 41.222 -41.830 -50.623 1.00 89.32 ? 503 NAG B O4 1 HETATM 6174 O O5 . NAG J 2 . ? 38.033 -41.754 -48.808 1.00 84.64 ? 503 NAG B O5 1 HETATM 6175 O O6 . NAG J 2 . ? 39.698 -41.904 -46.597 1.00 88.80 ? 503 NAG B O6 1 HETATM 6176 O O7 . NAG J 2 . ? 35.791 -39.621 -52.480 1.00 83.05 ? 503 NAG B O7 1 HETATM 6177 C C1 . BMA K 4 . ? 42.291 -41.022 -51.217 1.00 93.05 ? 504 BMA B C1 1 HETATM 6178 C C2 . BMA K 4 . ? 41.765 -40.046 -52.283 1.00 98.00 ? 504 BMA B C2 1 HETATM 6179 C C3 . BMA K 4 . ? 42.965 -39.382 -52.950 1.00 98.03 ? 504 BMA B C3 1 HETATM 6180 C C4 . BMA K 4 . ? 43.744 -38.622 -51.879 1.00 94.44 ? 504 BMA B C4 1 HETATM 6181 C C5 . BMA K 4 . ? 44.202 -39.597 -50.793 1.00 93.81 ? 504 BMA B C5 1 HETATM 6182 C C6 . BMA K 4 . ? 44.914 -38.917 -49.641 1.00 94.39 ? 504 BMA B C6 1 HETATM 6183 O O2 . BMA K 4 . ? 40.969 -39.057 -51.629 1.00 101.45 ? 504 BMA B O2 1 HETATM 6184 O O3 . BMA K 4 . ? 42.715 -38.599 -54.137 1.00 102.55 ? 504 BMA B O3 1 HETATM 6185 O O4 . BMA K 4 . ? 44.858 -37.931 -52.429 1.00 94.20 ? 504 BMA B O4 1 HETATM 6186 O O5 . BMA K 4 . ? 43.072 -40.309 -50.247 1.00 92.74 ? 504 BMA B O5 1 HETATM 6187 O O6 . BMA K 4 . ? 45.645 -39.804 -48.790 1.00 93.07 ? 504 BMA B O6 1 HETATM 6188 C C1 . BMA L 4 . ? 46.535 -40.667 -49.442 1.00 95.20 ? 505 BMA B C1 1 HETATM 6189 C C2 . BMA L 4 . ? 47.979 -40.339 -49.020 1.00 94.47 ? 505 BMA B C2 1 HETATM 6190 C C3 . BMA L 4 . ? 48.829 -41.602 -48.966 1.00 93.68 ? 505 BMA B C3 1 HETATM 6191 C C4 . BMA L 4 . ? 48.275 -42.608 -47.958 1.00 94.05 ? 505 BMA B C4 1 HETATM 6192 C C5 . BMA L 4 . ? 46.757 -42.770 -48.082 1.00 96.66 ? 505 BMA B C5 1 HETATM 6193 C C6 . BMA L 4 . ? 45.959 -42.434 -46.834 1.00 95.19 ? 505 BMA B C6 1 HETATM 6194 O O2 . BMA L 4 . ? 48.015 -39.658 -47.770 1.00 93.51 ? 505 BMA B O2 1 HETATM 6195 O O3 . BMA L 4 . ? 50.174 -41.256 -48.653 1.00 92.31 ? 505 BMA B O3 1 HETATM 6196 O O4 . BMA L 4 . ? 48.875 -43.882 -48.167 1.00 92.87 ? 505 BMA B O4 1 HETATM 6197 O O5 . BMA L 4 . ? 46.209 -42.054 -49.215 1.00 98.30 ? 505 BMA B O5 1 HETATM 6198 O O6 . BMA L 4 . ? 46.160 -41.105 -46.349 1.00 93.16 ? 505 BMA B O6 1 HETATM 6199 C C1 . BMA M 4 . ? 41.421 -38.263 -54.851 1.00 104.39 ? 506 BMA B C1 1 HETATM 6200 C C2 . BMA M 4 . ? 41.205 -39.165 -56.089 1.00 104.48 ? 506 BMA B C2 1 HETATM 6201 C C3 . BMA M 4 . ? 39.761 -39.663 -56.218 1.00 100.28 ? 506 BMA B C3 1 HETATM 6202 C C4 . BMA M 4 . ? 38.711 -38.592 -55.916 1.00 97.56 ? 506 BMA B C4 1 HETATM 6203 C C5 . BMA M 4 . ? 39.128 -37.665 -54.775 1.00 100.96 ? 506 BMA B C5 1 HETATM 6204 C C6 . BMA M 4 . ? 38.026 -37.384 -53.776 1.00 100.22 ? 506 BMA B C6 1 HETATM 6205 O O2 . BMA M 4 . ? 42.124 -40.254 -56.144 1.00 108.11 ? 506 BMA B O2 1 HETATM 6206 O O3 . BMA M 4 . ? 39.531 -40.819 -55.423 1.00 101.23 ? 506 BMA B O3 1 HETATM 6207 O O4 . BMA M 4 . ? 38.456 -37.817 -57.077 1.00 95.18 ? 506 BMA B O4 1 HETATM 6208 O O5 . BMA M 4 . ? 40.237 -38.228 -54.052 1.00 104.29 ? 506 BMA B O5 1 HETATM 6209 O O6 . BMA M 4 . ? 36.975 -36.603 -54.339 1.00 98.30 ? 506 BMA B O6 1 HETATM 6210 C C1 . NAG N 2 . ? -4.527 -3.985 -55.691 1.00 105.76 ? 567 NAG B C1 1 HETATM 6211 C C2 . NAG N 2 . ? -4.493 -3.984 -57.220 1.00 106.06 ? 567 NAG B C2 1 HETATM 6212 C C3 . NAG N 2 . ? -3.055 -3.723 -57.666 1.00 108.98 ? 567 NAG B C3 1 HETATM 6213 C C4 . NAG N 2 . ? -2.521 -2.425 -57.072 1.00 110.73 ? 567 NAG B C4 1 HETATM 6214 C C5 . NAG N 2 . ? -2.679 -2.432 -55.550 1.00 109.13 ? 567 NAG B C5 1 HETATM 6215 C C6 . NAG N 2 . ? -2.368 -1.100 -54.907 1.00 112.46 ? 567 NAG B C6 1 HETATM 6216 C C7 . NAG N 2 . ? -5.532 -5.421 -58.931 1.00 102.25 ? 567 NAG B C7 1 HETATM 6217 C C8 . NAG N 2 . ? -5.616 -6.831 -59.438 1.00 100.11 ? 567 NAG B C8 1 HETATM 6218 N N2 . NAG N 2 . ? -4.951 -5.263 -57.737 1.00 103.49 ? 567 NAG B N2 1 HETATM 6219 O O3 . NAG N 2 . ? -3.011 -3.661 -59.087 1.00 109.77 ? 567 NAG B O3 1 HETATM 6220 O O4 . NAG N 2 . ? -1.144 -2.331 -57.434 1.00 115.87 ? 567 NAG B O4 1 HETATM 6221 O O5 . NAG N 2 . ? -4.038 -2.737 -55.193 1.00 105.97 ? 567 NAG B O5 1 HETATM 6222 O O6 . NAG N 2 . ? -2.355 -1.195 -53.488 1.00 113.74 ? 567 NAG B O6 1 HETATM 6223 O O7 . NAG N 2 . ? -5.942 -4.467 -59.585 1.00 103.24 ? 567 NAG B O7 1 HETATM 6224 C C1 . NAG O 2 . ? -0.592 -1.068 -57.807 1.00 121.75 ? 569 NAG B C1 1 HETATM 6225 C C2 . NAG O 2 . ? 0.852 -1.011 -57.306 1.00 124.45 ? 569 NAG B C2 1 HETATM 6226 C C3 . NAG O 2 . ? 1.789 -0.661 -58.460 1.00 124.10 ? 569 NAG B C3 1 HETATM 6227 C C4 . NAG O 2 . ? 1.473 -1.517 -59.685 1.00 124.02 ? 569 NAG B C4 1 HETATM 6228 C C5 . NAG O 2 . ? 0.054 -1.272 -60.204 1.00 123.84 ? 569 NAG B C5 1 HETATM 6229 C C6 . NAG O 2 . ? -0.606 -2.513 -60.767 1.00 122.79 ? 569 NAG B C6 1 HETATM 6230 C C7 . NAG O 2 . ? 1.169 -0.359 -54.940 1.00 126.40 ? 569 NAG B C7 1 HETATM 6231 C C8 . NAG O 2 . ? 1.200 0.789 -53.976 1.00 125.27 ? 569 NAG B C8 1 HETATM 6232 N N2 . NAG O 2 . ? 0.970 -0.034 -56.233 1.00 126.30 ? 569 NAG B N2 1 HETATM 6233 O O3 . NAG O 2 . ? 3.130 -0.896 -58.044 1.00 122.99 ? 569 NAG B O3 1 HETATM 6234 O O4 . NAG O 2 . ? 2.400 -1.233 -60.729 1.00 123.14 ? 569 NAG B O4 1 HETATM 6235 O O5 . NAG O 2 . ? -0.818 -0.729 -59.189 1.00 123.40 ? 569 NAG B O5 1 HETATM 6236 O O6 . NAG O 2 . ? -1.950 -2.273 -61.179 1.00 121.51 ? 569 NAG B O6 1 HETATM 6237 O O7 . NAG O 2 . ? 1.315 -1.522 -54.571 1.00 127.12 ? 569 NAG B O7 1 HETATM 6238 O O . HOH P 5 . ? -16.573 -19.277 -35.140 1.00 67.45 ? 2001 HOH A O 1 HETATM 6239 O O . HOH P 5 . ? -5.970 -24.465 -38.350 1.00 69.49 ? 2002 HOH A O 1 HETATM 6240 O O . HOH P 5 . ? -54.071 11.981 -35.725 1.00 22.51 ? 2003 HOH A O 1 HETATM 6241 O O . HOH Q 5 . ? -13.033 -25.542 -43.468 1.00 43.75 ? 2001 HOH B O 1 HETATM 6242 O O . HOH Q 5 . ? -11.116 -28.485 -43.401 1.00 26.63 ? 2002 HOH B O 1 HETATM 6243 O O . HOH Q 5 . ? 23.647 -64.414 -37.166 1.00 33.66 ? 2003 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 MET 1 1 1 MET MET A . n A 1 2 ARG 2 2 2 ARG ARG A . n A 1 3 CYS 3 3 3 CYS CYS A . n A 1 4 ILE 4 4 4 ILE ILE A . n A 1 5 GLY 5 5 5 GLY GLY A . n A 1 6 ILE 6 6 6 ILE ILE A . n A 1 7 SER 7 7 7 SER SER A . n A 1 8 ASN 8 8 8 ASN ASN A . n A 1 9 ARG 9 9 9 ARG ARG A . n A 1 10 ASP 10 10 10 ASP ASP A . n A 1 11 PHE 11 11 11 PHE PHE A . n A 1 12 VAL 12 12 12 VAL VAL A . n A 1 13 GLU 13 13 13 GLU GLU A . n A 1 14 GLY 14 14 14 GLY GLY A . n A 1 15 VAL 15 15 15 VAL VAL A . n A 1 16 SER 16 16 16 SER SER A . n A 1 17 GLY 17 17 17 GLY GLY A . n A 1 18 GLY 18 18 18 GLY GLY A . n A 1 19 SER 19 19 19 SER SER A . n A 1 20 TRP 20 20 20 TRP TRP A . n A 1 21 VAL 21 21 21 VAL VAL A . n A 1 22 ASP 22 22 22 ASP ASP A . n A 1 23 ILE 23 23 23 ILE ILE A . n A 1 24 VAL 24 24 24 VAL VAL A . n A 1 25 LEU 25 25 25 LEU LEU A . n A 1 26 GLU 26 26 26 GLU GLU A . n A 1 27 HIS 27 27 27 HIS HIS A . n A 1 28 GLY 28 28 28 GLY GLY A . n A 1 29 SER 29 29 29 SER SER A . n A 1 30 CYS 30 30 30 CYS CYS A . n A 1 31 VAL 31 31 31 VAL VAL A . n A 1 32 THR 32 32 32 THR THR A . n A 1 33 THR 33 33 33 THR THR A . n A 1 34 MET 34 34 34 MET MET A . n A 1 35 ALA 35 35 35 ALA ALA A . n A 1 36 LYS 36 36 36 LYS LYS A . n A 1 37 ASN 37 37 37 ASN ASN A . n A 1 38 LYS 38 38 38 LYS LYS A . n A 1 39 PRO 39 39 39 PRO PRO A . n A 1 40 THR 40 40 40 THR THR A . n A 1 41 LEU 41 41 41 LEU LEU A . n A 1 42 ASP 42 42 42 ASP ASP A . n A 1 43 PHE 43 43 43 PHE PHE A . n A 1 44 GLU 44 44 44 GLU GLU A . n A 1 45 LEU 45 45 45 LEU LEU A . n A 1 46 ILE 46 46 46 ILE ILE A . n A 1 47 LYS 47 47 47 LYS LYS A . n A 1 48 THR 48 48 48 THR THR A . n A 1 49 GLU 49 49 49 GLU GLU A . n A 1 50 ALA 50 50 50 ALA ALA A . n A 1 51 LYS 51 51 51 LYS LYS A . n A 1 52 GLN 52 52 52 GLN GLN A . n A 1 53 PRO 53 53 53 PRO PRO A . n A 1 54 ALA 54 54 54 ALA ALA A . n A 1 55 THR 55 55 55 THR THR A . n A 1 56 LEU 56 56 56 LEU LEU A . n A 1 57 ARG 57 57 57 ARG ARG A . n A 1 58 LYS 58 58 58 LYS LYS A . n A 1 59 TYR 59 59 59 TYR TYR A . n A 1 60 CYS 60 60 60 CYS CYS A . n A 1 61 ILE 61 61 61 ILE ILE A . n A 1 62 GLU 62 62 62 GLU GLU A . n A 1 63 ALA 63 63 63 ALA ALA A . n A 1 64 LYS 64 64 64 LYS LYS A . n A 1 65 LEU 65 65 65 LEU LEU A . n A 1 66 THR 66 66 66 THR THR A . n A 1 67 ASN 67 67 67 ASN ASN A . n A 1 68 THR 68 68 68 THR THR A . n A 1 69 THR 69 69 69 THR THR A . n A 1 70 THR 70 70 70 THR THR A . n A 1 71 GLU 71 71 71 GLU GLU A . n A 1 72 SER 72 72 72 SER SER A . n A 1 73 ARG 73 73 73 ARG ARG A . n A 1 74 CYS 74 74 74 CYS CYS A . n A 1 75 PRO 75 75 75 PRO PRO A . n A 1 76 THR 76 76 76 THR THR A . n A 1 77 GLN 77 77 77 GLN GLN A . n A 1 78 GLY 78 78 78 GLY GLY A . n A 1 79 GLU 79 79 79 GLU GLU A . n A 1 80 PRO 80 80 80 PRO PRO A . n A 1 81 SER 81 81 81 SER SER A . n A 1 82 LEU 82 82 82 LEU LEU A . n A 1 83 ASN 83 83 83 ASN ASN A . n A 1 84 GLU 84 84 84 GLU GLU A . n A 1 85 GLU 85 85 85 GLU GLU A . n A 1 86 GLN 86 86 86 GLN GLN A . n A 1 87 ASP 87 87 87 ASP ASP A . n A 1 88 LYS 88 88 88 LYS LYS A . n A 1 89 ARG 89 89 89 ARG ARG A . n A 1 90 PHE 90 90 90 PHE PHE A . n A 1 91 ILE 91 91 91 ILE ILE A . n A 1 92 CYS 92 92 92 CYS CYS A . n A 1 93 LYS 93 93 93 LYS LYS A . n A 1 94 HIS 94 94 94 HIS HIS A . n A 1 95 SER 95 95 95 SER SER A . n A 1 96 MET 96 96 96 MET MET A . n A 1 97 VAL 97 97 97 VAL VAL A . n A 1 98 ASP 98 98 98 ASP ASP A . n A 1 99 ARG 99 99 99 ARG ARG A . n A 1 100 GLY 100 100 100 GLY GLY A . n A 1 101 TRP 101 101 101 TRP TRP A . n A 1 102 GLY 102 102 102 GLY GLY A . n A 1 103 ASN 103 103 103 ASN ASN A . n A 1 104 GLY 104 104 104 GLY GLY A . n A 1 105 CYS 105 105 105 CYS CYS A . n A 1 106 GLY 106 106 106 GLY GLY A . n A 1 107 LEU 107 107 107 LEU LEU A . n A 1 108 PHE 108 108 108 PHE PHE A . n A 1 109 GLY 109 109 109 GLY GLY A . n A 1 110 LYS 110 110 110 LYS LYS A . n A 1 111 GLY 111 111 111 GLY GLY A . n A 1 112 GLY 112 112 112 GLY GLY A . n A 1 113 ILE 113 113 113 ILE ILE A . n A 1 114 VAL 114 114 114 VAL VAL A . n A 1 115 THR 115 115 115 THR THR A . n A 1 116 CYS 116 116 116 CYS CYS A . n A 1 117 ALA 117 117 117 ALA ALA A . n A 1 118 LYS 118 118 118 LYS LYS A . n A 1 119 PHE 119 119 119 PHE PHE A . n A 1 120 THR 120 120 120 THR THR A . n A 1 121 CYS 121 121 121 CYS CYS A . n A 1 122 LYS 122 122 122 LYS LYS A . n A 1 123 LYS 123 123 123 LYS LYS A . n A 1 124 ASN 124 124 124 ASN ASN A . n A 1 125 MET 125 125 125 MET MET A . n A 1 126 GLU 126 126 126 GLU GLU A . n A 1 127 GLY 127 127 127 GLY GLY A . n A 1 128 LYS 128 128 128 LYS LYS A . n A 1 129 ILE 129 129 129 ILE ILE A . n A 1 130 VAL 130 130 130 VAL VAL A . n A 1 131 GLN 131 131 131 GLN GLN A . n A 1 132 PRO 132 132 132 PRO PRO A . n A 1 133 GLU 133 133 133 GLU GLU A . n A 1 134 ASN 134 134 134 ASN ASN A . n A 1 135 LEU 135 135 135 LEU LEU A . n A 1 136 GLU 136 136 136 GLU GLU A . n A 1 137 TYR 137 137 137 TYR TYR A . n A 1 138 THR 138 138 138 THR THR A . n A 1 139 ILE 139 139 139 ILE ILE A . n A 1 140 VAL 140 140 140 VAL VAL A . n A 1 141 ILE 141 141 141 ILE ILE A . n A 1 142 THR 142 142 142 THR THR A . n A 1 143 PRO 143 143 143 PRO PRO A . n A 1 144 HIS 144 144 144 HIS HIS A . n A 1 145 SER 145 145 145 SER SER A . n A 1 146 GLY 146 146 146 GLY GLY A . n A 1 147 GLU 147 147 147 GLU GLU A . n A 1 148 GLU 148 148 148 GLU GLU A . n A 1 149 HIS 149 149 149 HIS HIS A . n A 1 150 ALA 150 150 150 ALA ALA A . n A 1 151 VAL 151 151 151 VAL VAL A . n A 1 152 GLY 152 152 152 GLY GLY A . n A 1 153 ASN 153 153 153 ASN ASN A . n A 1 154 ASP 154 154 154 ASP ASP A . n A 1 155 THR 155 155 155 THR THR A . n A 1 156 GLY 156 156 156 GLY GLY A . n A 1 157 LYS 157 157 157 LYS LYS A . n A 1 158 HIS 158 158 158 HIS HIS A . n A 1 159 GLY 159 159 159 GLY GLY A . n A 1 160 LYS 160 160 160 LYS LYS A . n A 1 161 GLU 161 161 161 GLU GLU A . n A 1 162 ILE 162 162 162 ILE ILE A . n A 1 163 LYS 163 163 163 LYS LYS A . n A 1 164 ILE 164 164 164 ILE ILE A . n A 1 165 THR 165 165 165 THR THR A . n A 1 166 PRO 166 166 166 PRO PRO A . n A 1 167 GLN 167 167 167 GLN GLN A . n A 1 168 SER 168 168 168 SER SER A . n A 1 169 SER 169 169 169 SER SER A . n A 1 170 THR 170 170 170 THR THR A . n A 1 171 THR 171 171 171 THR THR A . n A 1 172 GLU 172 172 172 GLU GLU A . n A 1 173 ALA 173 173 173 ALA ALA A . n A 1 174 GLU 174 174 174 GLU GLU A . n A 1 175 LEU 175 175 175 LEU LEU A . n A 1 176 THR 176 176 176 THR THR A . n A 1 177 GLY 177 177 177 GLY GLY A . n A 1 178 TYR 178 178 178 TYR TYR A . n A 1 179 GLY 179 179 179 GLY GLY A . n A 1 180 THR 180 180 180 THR THR A . n A 1 181 VAL 181 181 181 VAL VAL A . n A 1 182 THR 182 182 182 THR THR A . n A 1 183 MET 183 183 183 MET MET A . n A 1 184 GLU 184 184 184 GLU GLU A . n A 1 185 CYS 185 185 185 CYS CYS A . n A 1 186 SER 186 186 186 SER SER A . n A 1 187 PRO 187 187 187 PRO PRO A . n A 1 188 ARG 188 188 188 ARG ARG A . n A 1 189 THR 189 189 189 THR THR A . n A 1 190 GLY 190 190 ? ? ? A . n A 1 191 LEU 191 191 ? ? ? A . n A 1 192 ASP 192 192 192 ASP ASP A . n A 1 193 PHE 193 193 193 PHE PHE A . n A 1 194 ASN 194 194 194 ASN ASN A . n A 1 195 GLU 195 195 195 GLU GLU A . n A 1 196 MET 196 196 196 MET MET A . n A 1 197 VAL 197 197 197 VAL VAL A . n A 1 198 LEU 198 198 198 LEU LEU A . n A 1 199 LEU 199 199 199 LEU LEU A . n A 1 200 GLN 200 200 200 GLN GLN A . n A 1 201 MET 201 201 201 MET MET A . n A 1 202 GLU 202 202 202 GLU GLU A . n A 1 203 ASP 203 203 203 ASP ASP A . n A 1 204 LYS 204 204 204 LYS LYS A . n A 1 205 ALA 205 205 205 ALA ALA A . n A 1 206 TRP 206 206 206 TRP TRP A . n A 1 207 LEU 207 207 207 LEU LEU A . n A 1 208 VAL 208 208 208 VAL VAL A . n A 1 209 HIS 209 209 209 HIS HIS A . n A 1 210 ARG 210 210 210 ARG ARG A . n A 1 211 GLN 211 211 211 GLN GLN A . n A 1 212 TRP 212 212 212 TRP TRP A . n A 1 213 PHE 213 213 213 PHE PHE A . n A 1 214 LEU 214 214 214 LEU LEU A . n A 1 215 ASP 215 215 215 ASP ASP A . n A 1 216 LEU 216 216 216 LEU LEU A . n A 1 217 PRO 217 217 217 PRO PRO A . n A 1 218 LEU 218 218 218 LEU LEU A . n A 1 219 PRO 219 219 219 PRO PRO A . n A 1 220 TRP 220 220 220 TRP TRP A . n A 1 221 LEU 221 221 221 LEU LEU A . n A 1 222 PRO 222 222 222 PRO PRO A . n A 1 223 GLY 223 223 223 GLY GLY A . n A 1 224 ALA 224 224 224 ALA ALA A . n A 1 225 ASP 225 225 225 ASP ASP A . n A 1 226 THR 226 226 226 THR THR A . n A 1 227 GLN 227 227 227 GLN GLN A . n A 1 228 GLY 228 228 228 GLY GLY A . n A 1 229 SER 229 229 229 SER SER A . n A 1 230 ASN 230 230 230 ASN ASN A . n A 1 231 TRP 231 231 231 TRP TRP A . n A 1 232 ILE 232 232 232 ILE ILE A . n A 1 233 GLN 233 233 233 GLN GLN A . n A 1 234 LYS 234 234 234 LYS LYS A . n A 1 235 GLU 235 235 235 GLU GLU A . n A 1 236 THR 236 236 236 THR THR A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 VAL 238 238 238 VAL VAL A . n A 1 239 THR 239 239 239 THR THR A . n A 1 240 PHE 240 240 240 PHE PHE A . n A 1 241 LYS 241 241 241 LYS LYS A . n A 1 242 ASN 242 242 242 ASN ASN A . n A 1 243 PRO 243 243 243 PRO PRO A . n A 1 244 HIS 244 244 244 HIS HIS A . n A 1 245 ALA 245 245 245 ALA ALA A . n A 1 246 LYS 246 246 246 LYS LYS A . n A 1 247 LYS 247 247 247 LYS LYS A . n A 1 248 GLN 248 248 248 GLN GLN A . n A 1 249 ASP 249 249 249 ASP ASP A . n A 1 250 VAL 250 250 250 VAL VAL A . n A 1 251 VAL 251 251 251 VAL VAL A . n A 1 252 VAL 252 252 252 VAL VAL A . n A 1 253 LEU 253 253 253 LEU LEU A . n A 1 254 GLY 254 254 254 GLY GLY A . n A 1 255 SER 255 255 255 SER SER A . n A 1 256 GLN 256 256 256 GLN GLN A . n A 1 257 GLU 257 257 257 GLU GLU A . n A 1 258 GLY 258 258 258 GLY GLY A . n A 1 259 ALA 259 259 259 ALA ALA A . n A 1 260 MET 260 260 260 MET MET A . n A 1 261 HIS 261 261 261 HIS HIS A . n A 1 262 THR 262 262 262 THR THR A . n A 1 263 ALA 263 263 263 ALA ALA A . n A 1 264 LEU 264 264 264 LEU LEU A . n A 1 265 THR 265 265 265 THR THR A . n A 1 266 GLY 266 266 266 GLY GLY A . n A 1 267 ALA 267 267 267 ALA ALA A . n A 1 268 THR 268 268 268 THR THR A . n A 1 269 GLU 269 269 269 GLU GLU A . n A 1 270 ILE 270 270 270 ILE ILE A . n A 1 271 GLN 271 271 271 GLN GLN A . n A 1 272 MET 272 272 272 MET MET A . n A 1 273 SER 273 273 273 SER SER A . n A 1 274 SER 274 274 274 SER SER A . n A 1 275 GLY 275 275 275 GLY GLY A . n A 1 276 ASN 276 276 276 ASN ASN A . n A 1 277 LEU 277 277 277 LEU LEU A . n A 1 278 LEU 278 278 278 LEU LEU A . n A 1 279 PHE 279 279 279 PHE PHE A . n A 1 280 THR 280 280 ? ? ? A . n A 1 281 GLY 281 281 ? ? ? A . n A 1 282 HIS 282 282 282 HIS HIS A . n A 1 283 LEU 283 283 283 LEU LEU A . n A 1 284 LYS 284 284 284 LYS LYS A . n A 1 285 CYS 285 285 285 CYS CYS A . n A 1 286 ARG 286 286 286 ARG ARG A . n A 1 287 LEU 287 287 287 LEU LEU A . n A 1 288 ARG 288 288 288 ARG ARG A . n A 1 289 MET 289 289 289 MET MET A . n A 1 290 ASP 290 290 290 ASP ASP A . n A 1 291 LYS 291 291 291 LYS LYS A . n A 1 292 LEU 292 292 292 LEU LEU A . n A 1 293 GLN 293 293 293 GLN GLN A . n A 1 294 LEU 294 294 294 LEU LEU A . n A 1 295 LYS 295 295 295 LYS LYS A . n A 1 296 GLY 296 296 296 GLY GLY A . n A 1 297 MET 297 297 297 MET MET A . n A 1 298 SER 298 298 298 SER SER A . n A 1 299 TYR 299 299 299 TYR TYR A . n A 1 300 SER 300 300 300 SER SER A . n A 1 301 MET 301 301 301 MET MET A . n A 1 302 CYS 302 302 302 CYS CYS A . n A 1 303 THR 303 303 303 THR THR A . n A 1 304 GLY 304 304 304 GLY GLY A . n A 1 305 LYS 305 305 305 LYS LYS A . n A 1 306 PHE 306 306 306 PHE PHE A . n A 1 307 LYS 307 307 307 LYS LYS A . n A 1 308 ILE 308 308 308 ILE ILE A . n A 1 309 VAL 309 309 309 VAL VAL A . n A 1 310 LYS 310 310 310 LYS LYS A . n A 1 311 GLU 311 311 311 GLU GLU A . n A 1 312 ILE 312 312 312 ILE ILE A . n A 1 313 ALA 313 313 313 ALA ALA A . n A 1 314 GLU 314 314 314 GLU GLU A . n A 1 315 THR 315 315 315 THR THR A . n A 1 316 GLN 316 316 316 GLN GLN A . n A 1 317 HIS 317 317 317 HIS HIS A . n A 1 318 GLY 318 318 318 GLY GLY A . n A 1 319 THR 319 319 319 THR THR A . n A 1 320 ILE 320 320 320 ILE ILE A . n A 1 321 VAL 321 321 321 VAL VAL A . n A 1 322 ILE 322 322 322 ILE ILE A . n A 1 323 ARG 323 323 323 ARG ARG A . n A 1 324 VAL 324 324 324 VAL VAL A . n A 1 325 GLN 325 325 325 GLN GLN A . n A 1 326 TYR 326 326 326 TYR TYR A . n A 1 327 GLU 327 327 327 GLU GLU A . n A 1 328 GLY 328 328 328 GLY GLY A . n A 1 329 ASP 329 329 329 ASP ASP A . n A 1 330 GLY 330 330 330 GLY GLY A . n A 1 331 SER 331 331 331 SER SER A . n A 1 332 PRO 332 332 332 PRO PRO A . n A 1 333 CYS 333 333 333 CYS CYS A . n A 1 334 LYS 334 334 334 LYS LYS A . n A 1 335 ILE 335 335 335 ILE ILE A . n A 1 336 PRO 336 336 336 PRO PRO A . n A 1 337 PHE 337 337 337 PHE PHE A . n A 1 338 GLU 338 338 338 GLU GLU A . n A 1 339 ILE 339 339 339 ILE ILE A . n A 1 340 THR 340 340 340 THR THR A . n A 1 341 ASP 341 341 341 ASP ASP A . n A 1 342 LEU 342 342 342 LEU LEU A . n A 1 343 GLU 343 343 343 GLU GLU A . n A 1 344 LYS 344 344 344 LYS LYS A . n A 1 345 ARG 345 345 345 ARG ARG A . n A 1 346 HIS 346 346 346 HIS HIS A . n A 1 347 VAL 347 347 347 VAL VAL A . n A 1 348 LEU 348 348 348 LEU LEU A . n A 1 349 GLY 349 349 349 GLY GLY A . n A 1 350 ARG 350 350 350 ARG ARG A . n A 1 351 LEU 351 351 351 LEU LEU A . n A 1 352 ILE 352 352 352 ILE ILE A . n A 1 353 THR 353 353 353 THR THR A . n A 1 354 VAL 354 354 354 VAL VAL A . n A 1 355 ASN 355 355 355 ASN ASN A . n A 1 356 PRO 356 356 356 PRO PRO A . n A 1 357 ILE 357 357 357 ILE ILE A . n A 1 358 VAL 358 358 358 VAL VAL A . n A 1 359 THR 359 359 359 THR THR A . n A 1 360 GLU 360 360 360 GLU GLU A . n A 1 361 LYS 361 361 361 LYS LYS A . n A 1 362 ASP 362 362 362 ASP ASP A . n A 1 363 SER 363 363 363 SER SER A . n A 1 364 PRO 364 364 364 PRO PRO A . n A 1 365 VAL 365 365 365 VAL VAL A . n A 1 366 ASN 366 366 366 ASN ASN A . n A 1 367 ILE 367 367 367 ILE ILE A . n A 1 368 GLU 368 368 368 GLU GLU A . n A 1 369 ALA 369 369 369 ALA ALA A . n A 1 370 GLU 370 370 370 GLU GLU A . n A 1 371 PRO 371 371 371 PRO PRO A . n A 1 372 PRO 372 372 372 PRO PRO A . n A 1 373 PHE 373 373 373 PHE PHE A . n A 1 374 GLY 374 374 374 GLY GLY A . n A 1 375 ASP 375 375 375 ASP ASP A . n A 1 376 SER 376 376 376 SER SER A . n A 1 377 TYR 377 377 377 TYR TYR A . n A 1 378 ILE 378 378 378 ILE ILE A . n A 1 379 ILE 379 379 379 ILE ILE A . n A 1 380 VAL 380 380 380 VAL VAL A . n A 1 381 GLY 381 381 381 GLY GLY A . n A 1 382 VAL 382 382 382 VAL VAL A . n A 1 383 GLU 383 383 383 GLU GLU A . n A 1 384 PRO 384 384 384 PRO PRO A . n A 1 385 GLY 385 385 385 GLY GLY A . n A 1 386 GLN 386 386 386 GLN GLN A . n A 1 387 LEU 387 387 387 LEU LEU A . n A 1 388 LYS 388 388 388 LYS LYS A . n A 1 389 LEU 389 389 389 LEU LEU A . n A 1 390 ASN 390 390 390 ASN ASN A . n A 1 391 TRP 391 391 391 TRP TRP A . n A 1 392 LEU 392 392 392 LEU LEU A . n A 1 393 ARG 393 393 393 ARG ARG A . n A 1 394 PRO 394 394 394 PRO PRO A . n A 1 395 LEU 395 395 395 LEU LEU A . n A 1 396 GLU 396 396 ? ? ? A . n A 1 397 SER 397 397 ? ? ? A . n A 1 398 ARG 398 398 ? ? ? A . n A 1 399 GLY 399 399 ? ? ? A . n A 1 400 PRO 400 400 ? ? ? A . n A 1 401 PHE 401 401 ? ? ? A . n A 1 402 GLU 402 402 ? ? ? A . n A 1 403 GLY 403 403 ? ? ? A . n A 1 404 LYS 404 404 ? ? ? A . n A 1 405 PRO 405 405 ? ? ? A . n A 1 406 ILE 406 406 ? ? ? A . n A 1 407 PRO 407 407 ? ? ? A . n A 1 408 ASN 408 408 ? ? ? A . n A 1 409 PRO 409 409 ? ? ? A . n A 1 410 LEU 410 410 ? ? ? A . n A 1 411 LEU 411 411 ? ? ? A . n A 1 412 GLY 412 412 ? ? ? A . n A 1 413 LEU 413 413 ? ? ? A . n A 1 414 ASP 414 414 ? ? ? A . n A 1 415 SER 415 415 ? ? ? A . n A 1 416 THR 416 416 ? ? ? A . n A 1 417 ARG 417 417 ? ? ? A . n A 1 418 THR 418 418 ? ? ? A . n A 1 419 GLY 419 419 ? ? ? A . n A 1 420 HIS 420 420 ? ? ? A . n A 1 421 HIS 421 421 ? ? ? A . n A 1 422 HIS 422 422 ? ? ? A . n B 1 1 MET 1 1 1 MET MET B . n B 1 2 ARG 2 2 2 ARG ARG B . n B 1 3 CYS 3 3 3 CYS CYS B . n B 1 4 ILE 4 4 4 ILE ILE B . n B 1 5 GLY 5 5 5 GLY GLY B . n B 1 6 ILE 6 6 6 ILE ILE B . n B 1 7 SER 7 7 7 SER SER B . n B 1 8 ASN 8 8 8 ASN ASN B . n B 1 9 ARG 9 9 9 ARG ARG B . n B 1 10 ASP 10 10 10 ASP ASP B . n B 1 11 PHE 11 11 11 PHE PHE B . n B 1 12 VAL 12 12 12 VAL VAL B . n B 1 13 GLU 13 13 13 GLU GLU B . n B 1 14 GLY 14 14 14 GLY GLY B . n B 1 15 VAL 15 15 ? ? ? B . n B 1 16 SER 16 16 ? ? ? B . n B 1 17 GLY 17 17 ? ? ? B . n B 1 18 GLY 18 18 ? ? ? B . n B 1 19 SER 19 19 ? ? ? B . n B 1 20 TRP 20 20 20 TRP TRP B . n B 1 21 VAL 21 21 21 VAL VAL B . n B 1 22 ASP 22 22 22 ASP ASP B . n B 1 23 ILE 23 23 23 ILE ILE B . n B 1 24 VAL 24 24 24 VAL VAL B . n B 1 25 LEU 25 25 25 LEU LEU B . n B 1 26 GLU 26 26 26 GLU GLU B . n B 1 27 HIS 27 27 27 HIS HIS B . n B 1 28 GLY 28 28 28 GLY GLY B . n B 1 29 SER 29 29 29 SER SER B . n B 1 30 CYS 30 30 30 CYS CYS B . n B 1 31 VAL 31 31 31 VAL VAL B . n B 1 32 THR 32 32 32 THR THR B . n B 1 33 THR 33 33 33 THR THR B . n B 1 34 MET 34 34 34 MET MET B . n B 1 35 ALA 35 35 35 ALA ALA B . n B 1 36 LYS 36 36 36 LYS LYS B . n B 1 37 ASN 37 37 37 ASN ASN B . n B 1 38 LYS 38 38 38 LYS LYS B . n B 1 39 PRO 39 39 39 PRO PRO B . n B 1 40 THR 40 40 40 THR THR B . n B 1 41 LEU 41 41 41 LEU LEU B . n B 1 42 ASP 42 42 42 ASP ASP B . n B 1 43 PHE 43 43 43 PHE PHE B . n B 1 44 GLU 44 44 44 GLU GLU B . n B 1 45 LEU 45 45 45 LEU LEU B . n B 1 46 ILE 46 46 46 ILE ILE B . n B 1 47 LYS 47 47 47 LYS LYS B . n B 1 48 THR 48 48 48 THR THR B . n B 1 49 GLU 49 49 49 GLU GLU B . n B 1 50 ALA 50 50 50 ALA ALA B . n B 1 51 LYS 51 51 51 LYS LYS B . n B 1 52 GLN 52 52 52 GLN GLN B . n B 1 53 PRO 53 53 53 PRO PRO B . n B 1 54 ALA 54 54 54 ALA ALA B . n B 1 55 THR 55 55 55 THR THR B . n B 1 56 LEU 56 56 56 LEU LEU B . n B 1 57 ARG 57 57 57 ARG ARG B . n B 1 58 LYS 58 58 58 LYS LYS B . n B 1 59 TYR 59 59 59 TYR TYR B . n B 1 60 CYS 60 60 60 CYS CYS B . n B 1 61 ILE 61 61 61 ILE ILE B . n B 1 62 GLU 62 62 62 GLU GLU B . n B 1 63 ALA 63 63 63 ALA ALA B . n B 1 64 LYS 64 64 64 LYS LYS B . n B 1 65 LEU 65 65 65 LEU LEU B . n B 1 66 THR 66 66 66 THR THR B . n B 1 67 ASN 67 67 67 ASN ASN B . n B 1 68 THR 68 68 68 THR THR B . n B 1 69 THR 69 69 69 THR THR B . n B 1 70 THR 70 70 70 THR THR B . n B 1 71 GLU 71 71 71 GLU GLU B . n B 1 72 SER 72 72 72 SER SER B . n B 1 73 ARG 73 73 73 ARG ARG B . n B 1 74 CYS 74 74 74 CYS CYS B . n B 1 75 PRO 75 75 75 PRO PRO B . n B 1 76 THR 76 76 76 THR THR B . n B 1 77 GLN 77 77 77 GLN GLN B . n B 1 78 GLY 78 78 78 GLY GLY B . n B 1 79 GLU 79 79 79 GLU GLU B . n B 1 80 PRO 80 80 80 PRO PRO B . n B 1 81 SER 81 81 81 SER SER B . n B 1 82 LEU 82 82 82 LEU LEU B . n B 1 83 ASN 83 83 83 ASN ASN B . n B 1 84 GLU 84 84 84 GLU GLU B . n B 1 85 GLU 85 85 85 GLU GLU B . n B 1 86 GLN 86 86 86 GLN GLN B . n B 1 87 ASP 87 87 87 ASP ASP B . n B 1 88 LYS 88 88 88 LYS LYS B . n B 1 89 ARG 89 89 89 ARG ARG B . n B 1 90 PHE 90 90 90 PHE PHE B . n B 1 91 ILE 91 91 91 ILE ILE B . n B 1 92 CYS 92 92 92 CYS CYS B . n B 1 93 LYS 93 93 93 LYS LYS B . n B 1 94 HIS 94 94 94 HIS HIS B . n B 1 95 SER 95 95 95 SER SER B . n B 1 96 MET 96 96 96 MET MET B . n B 1 97 VAL 97 97 97 VAL VAL B . n B 1 98 ASP 98 98 98 ASP ASP B . n B 1 99 ARG 99 99 99 ARG ARG B . n B 1 100 GLY 100 100 100 GLY GLY B . n B 1 101 TRP 101 101 101 TRP TRP B . n B 1 102 GLY 102 102 102 GLY GLY B . n B 1 103 ASN 103 103 103 ASN ASN B . n B 1 104 GLY 104 104 104 GLY GLY B . n B 1 105 CYS 105 105 105 CYS CYS B . n B 1 106 GLY 106 106 106 GLY GLY B . n B 1 107 LEU 107 107 107 LEU LEU B . n B 1 108 PHE 108 108 108 PHE PHE B . n B 1 109 GLY 109 109 109 GLY GLY B . n B 1 110 LYS 110 110 110 LYS LYS B . n B 1 111 GLY 111 111 111 GLY GLY B . n B 1 112 GLY 112 112 112 GLY GLY B . n B 1 113 ILE 113 113 113 ILE ILE B . n B 1 114 VAL 114 114 114 VAL VAL B . n B 1 115 THR 115 115 115 THR THR B . n B 1 116 CYS 116 116 116 CYS CYS B . n B 1 117 ALA 117 117 117 ALA ALA B . n B 1 118 LYS 118 118 118 LYS LYS B . n B 1 119 PHE 119 119 119 PHE PHE B . n B 1 120 THR 120 120 120 THR THR B . n B 1 121 CYS 121 121 121 CYS CYS B . n B 1 122 LYS 122 122 122 LYS LYS B . n B 1 123 LYS 123 123 123 LYS LYS B . n B 1 124 ASN 124 124 124 ASN ASN B . n B 1 125 MET 125 125 125 MET MET B . n B 1 126 GLU 126 126 126 GLU GLU B . n B 1 127 GLY 127 127 127 GLY GLY B . n B 1 128 LYS 128 128 128 LYS LYS B . n B 1 129 ILE 129 129 129 ILE ILE B . n B 1 130 VAL 130 130 130 VAL VAL B . n B 1 131 GLN 131 131 131 GLN GLN B . n B 1 132 PRO 132 132 132 PRO PRO B . n B 1 133 GLU 133 133 133 GLU GLU B . n B 1 134 ASN 134 134 134 ASN ASN B . n B 1 135 LEU 135 135 135 LEU LEU B . n B 1 136 GLU 136 136 136 GLU GLU B . n B 1 137 TYR 137 137 137 TYR TYR B . n B 1 138 THR 138 138 138 THR THR B . n B 1 139 ILE 139 139 139 ILE ILE B . n B 1 140 VAL 140 140 140 VAL VAL B . n B 1 141 ILE 141 141 141 ILE ILE B . n B 1 142 THR 142 142 142 THR THR B . n B 1 143 PRO 143 143 143 PRO PRO B . n B 1 144 HIS 144 144 144 HIS HIS B . n B 1 145 SER 145 145 145 SER SER B . n B 1 146 GLY 146 146 146 GLY GLY B . n B 1 147 GLU 147 147 147 GLU GLU B . n B 1 148 GLU 148 148 148 GLU GLU B . n B 1 149 HIS 149 149 149 HIS HIS B . n B 1 150 ALA 150 150 150 ALA ALA B . n B 1 151 VAL 151 151 151 VAL VAL B . n B 1 152 GLY 152 152 152 GLY GLY B . n B 1 153 ASN 153 153 153 ASN ASN B . n B 1 154 ASP 154 154 154 ASP ASP B . n B 1 155 THR 155 155 155 THR THR B . n B 1 156 GLY 156 156 156 GLY GLY B . n B 1 157 LYS 157 157 157 LYS LYS B . n B 1 158 HIS 158 158 158 HIS HIS B . n B 1 159 GLY 159 159 159 GLY GLY B . n B 1 160 LYS 160 160 160 LYS LYS B . n B 1 161 GLU 161 161 161 GLU GLU B . n B 1 162 ILE 162 162 162 ILE ILE B . n B 1 163 LYS 163 163 163 LYS LYS B . n B 1 164 ILE 164 164 164 ILE ILE B . n B 1 165 THR 165 165 165 THR THR B . n B 1 166 PRO 166 166 166 PRO PRO B . n B 1 167 GLN 167 167 167 GLN GLN B . n B 1 168 SER 168 168 168 SER SER B . n B 1 169 SER 169 169 169 SER SER B . n B 1 170 THR 170 170 170 THR THR B . n B 1 171 THR 171 171 171 THR THR B . n B 1 172 GLU 172 172 172 GLU GLU B . n B 1 173 ALA 173 173 173 ALA ALA B . n B 1 174 GLU 174 174 174 GLU GLU B . n B 1 175 LEU 175 175 175 LEU LEU B . n B 1 176 THR 176 176 176 THR THR B . n B 1 177 GLY 177 177 177 GLY GLY B . n B 1 178 TYR 178 178 178 TYR TYR B . n B 1 179 GLY 179 179 179 GLY GLY B . n B 1 180 THR 180 180 180 THR THR B . n B 1 181 VAL 181 181 181 VAL VAL B . n B 1 182 THR 182 182 182 THR THR B . n B 1 183 MET 183 183 183 MET MET B . n B 1 184 GLU 184 184 184 GLU GLU B . n B 1 185 CYS 185 185 185 CYS CYS B . n B 1 186 SER 186 186 186 SER SER B . n B 1 187 PRO 187 187 187 PRO PRO B . n B 1 188 ARG 188 188 188 ARG ARG B . n B 1 189 THR 189 189 189 THR THR B . n B 1 190 GLY 190 190 190 GLY GLY B . n B 1 191 LEU 191 191 191 LEU LEU B . n B 1 192 ASP 192 192 192 ASP ASP B . n B 1 193 PHE 193 193 193 PHE PHE B . n B 1 194 ASN 194 194 194 ASN ASN B . n B 1 195 GLU 195 195 195 GLU GLU B . n B 1 196 MET 196 196 196 MET MET B . n B 1 197 VAL 197 197 197 VAL VAL B . n B 1 198 LEU 198 198 198 LEU LEU B . n B 1 199 LEU 199 199 199 LEU LEU B . n B 1 200 GLN 200 200 200 GLN GLN B . n B 1 201 MET 201 201 201 MET MET B . n B 1 202 GLU 202 202 202 GLU GLU B . n B 1 203 ASP 203 203 203 ASP ASP B . n B 1 204 LYS 204 204 204 LYS LYS B . n B 1 205 ALA 205 205 205 ALA ALA B . n B 1 206 TRP 206 206 206 TRP TRP B . n B 1 207 LEU 207 207 207 LEU LEU B . n B 1 208 VAL 208 208 208 VAL VAL B . n B 1 209 HIS 209 209 209 HIS HIS B . n B 1 210 ARG 210 210 210 ARG ARG B . n B 1 211 GLN 211 211 211 GLN GLN B . n B 1 212 TRP 212 212 212 TRP TRP B . n B 1 213 PHE 213 213 213 PHE PHE B . n B 1 214 LEU 214 214 214 LEU LEU B . n B 1 215 ASP 215 215 215 ASP ASP B . n B 1 216 LEU 216 216 216 LEU LEU B . n B 1 217 PRO 217 217 217 PRO PRO B . n B 1 218 LEU 218 218 218 LEU LEU B . n B 1 219 PRO 219 219 219 PRO PRO B . n B 1 220 TRP 220 220 220 TRP TRP B . n B 1 221 LEU 221 221 221 LEU LEU B . n B 1 222 PRO 222 222 222 PRO PRO B . n B 1 223 GLY 223 223 223 GLY GLY B . n B 1 224 ALA 224 224 224 ALA ALA B . n B 1 225 ASP 225 225 225 ASP ASP B . n B 1 226 THR 226 226 226 THR THR B . n B 1 227 GLN 227 227 227 GLN GLN B . n B 1 228 GLY 228 228 228 GLY GLY B . n B 1 229 SER 229 229 229 SER SER B . n B 1 230 ASN 230 230 230 ASN ASN B . n B 1 231 TRP 231 231 231 TRP TRP B . n B 1 232 ILE 232 232 232 ILE ILE B . n B 1 233 GLN 233 233 233 GLN GLN B . n B 1 234 LYS 234 234 234 LYS LYS B . n B 1 235 GLU 235 235 235 GLU GLU B . n B 1 236 THR 236 236 236 THR THR B . n B 1 237 LEU 237 237 237 LEU LEU B . n B 1 238 VAL 238 238 238 VAL VAL B . n B 1 239 THR 239 239 239 THR THR B . n B 1 240 PHE 240 240 240 PHE PHE B . n B 1 241 LYS 241 241 241 LYS LYS B . n B 1 242 ASN 242 242 242 ASN ASN B . n B 1 243 PRO 243 243 243 PRO PRO B . n B 1 244 HIS 244 244 244 HIS HIS B . n B 1 245 ALA 245 245 245 ALA ALA B . n B 1 246 LYS 246 246 246 LYS LYS B . n B 1 247 LYS 247 247 247 LYS LYS B . n B 1 248 GLN 248 248 248 GLN GLN B . n B 1 249 ASP 249 249 249 ASP ASP B . n B 1 250 VAL 250 250 250 VAL VAL B . n B 1 251 VAL 251 251 251 VAL VAL B . n B 1 252 VAL 252 252 252 VAL VAL B . n B 1 253 LEU 253 253 253 LEU LEU B . n B 1 254 GLY 254 254 254 GLY GLY B . n B 1 255 SER 255 255 255 SER SER B . n B 1 256 GLN 256 256 256 GLN GLN B . n B 1 257 GLU 257 257 257 GLU GLU B . n B 1 258 GLY 258 258 258 GLY GLY B . n B 1 259 ALA 259 259 259 ALA ALA B . n B 1 260 MET 260 260 260 MET MET B . n B 1 261 HIS 261 261 261 HIS HIS B . n B 1 262 THR 262 262 262 THR THR B . n B 1 263 ALA 263 263 263 ALA ALA B . n B 1 264 LEU 264 264 264 LEU LEU B . n B 1 265 THR 265 265 265 THR THR B . n B 1 266 GLY 266 266 266 GLY GLY B . n B 1 267 ALA 267 267 267 ALA ALA B . n B 1 268 THR 268 268 268 THR THR B . n B 1 269 GLU 269 269 269 GLU GLU B . n B 1 270 ILE 270 270 270 ILE ILE B . n B 1 271 GLN 271 271 271 GLN GLN B . n B 1 272 MET 272 272 272 MET MET B . n B 1 273 SER 273 273 273 SER SER B . n B 1 274 SER 274 274 274 SER SER B . n B 1 275 GLY 275 275 275 GLY GLY B . n B 1 276 ASN 276 276 276 ASN ASN B . n B 1 277 LEU 277 277 277 LEU LEU B . n B 1 278 LEU 278 278 278 LEU LEU B . n B 1 279 PHE 279 279 279 PHE PHE B . n B 1 280 THR 280 280 280 THR THR B . n B 1 281 GLY 281 281 281 GLY GLY B . n B 1 282 HIS 282 282 282 HIS HIS B . n B 1 283 LEU 283 283 283 LEU LEU B . n B 1 284 LYS 284 284 284 LYS LYS B . n B 1 285 CYS 285 285 285 CYS CYS B . n B 1 286 ARG 286 286 286 ARG ARG B . n B 1 287 LEU 287 287 287 LEU LEU B . n B 1 288 ARG 288 288 288 ARG ARG B . n B 1 289 MET 289 289 289 MET MET B . n B 1 290 ASP 290 290 290 ASP ASP B . n B 1 291 LYS 291 291 291 LYS LYS B . n B 1 292 LEU 292 292 292 LEU LEU B . n B 1 293 GLN 293 293 293 GLN GLN B . n B 1 294 LEU 294 294 294 LEU LEU B . n B 1 295 LYS 295 295 295 LYS LYS B . n B 1 296 GLY 296 296 296 GLY GLY B . n B 1 297 MET 297 297 297 MET MET B . n B 1 298 SER 298 298 298 SER SER B . n B 1 299 TYR 299 299 299 TYR TYR B . n B 1 300 SER 300 300 300 SER SER B . n B 1 301 MET 301 301 301 MET MET B . n B 1 302 CYS 302 302 302 CYS CYS B . n B 1 303 THR 303 303 303 THR THR B . n B 1 304 GLY 304 304 304 GLY GLY B . n B 1 305 LYS 305 305 305 LYS LYS B . n B 1 306 PHE 306 306 306 PHE PHE B . n B 1 307 LYS 307 307 307 LYS LYS B . n B 1 308 ILE 308 308 308 ILE ILE B . n B 1 309 VAL 309 309 309 VAL VAL B . n B 1 310 LYS 310 310 310 LYS LYS B . n B 1 311 GLU 311 311 311 GLU GLU B . n B 1 312 ILE 312 312 312 ILE ILE B . n B 1 313 ALA 313 313 313 ALA ALA B . n B 1 314 GLU 314 314 314 GLU GLU B . n B 1 315 THR 315 315 315 THR THR B . n B 1 316 GLN 316 316 316 GLN GLN B . n B 1 317 HIS 317 317 317 HIS HIS B . n B 1 318 GLY 318 318 318 GLY GLY B . n B 1 319 THR 319 319 319 THR THR B . n B 1 320 ILE 320 320 320 ILE ILE B . n B 1 321 VAL 321 321 321 VAL VAL B . n B 1 322 ILE 322 322 322 ILE ILE B . n B 1 323 ARG 323 323 323 ARG ARG B . n B 1 324 VAL 324 324 324 VAL VAL B . n B 1 325 GLN 325 325 325 GLN GLN B . n B 1 326 TYR 326 326 326 TYR TYR B . n B 1 327 GLU 327 327 327 GLU GLU B . n B 1 328 GLY 328 328 328 GLY GLY B . n B 1 329 ASP 329 329 329 ASP ASP B . n B 1 330 GLY 330 330 330 GLY GLY B . n B 1 331 SER 331 331 331 SER SER B . n B 1 332 PRO 332 332 332 PRO PRO B . n B 1 333 CYS 333 333 333 CYS CYS B . n B 1 334 LYS 334 334 334 LYS LYS B . n B 1 335 ILE 335 335 335 ILE ILE B . n B 1 336 PRO 336 336 336 PRO PRO B . n B 1 337 PHE 337 337 337 PHE PHE B . n B 1 338 GLU 338 338 338 GLU GLU B . n B 1 339 ILE 339 339 339 ILE ILE B . n B 1 340 THR 340 340 340 THR THR B . n B 1 341 ASP 341 341 341 ASP ASP B . n B 1 342 LEU 342 342 342 LEU LEU B . n B 1 343 GLU 343 343 343 GLU GLU B . n B 1 344 LYS 344 344 344 LYS LYS B . n B 1 345 ARG 345 345 345 ARG ARG B . n B 1 346 HIS 346 346 346 HIS HIS B . n B 1 347 VAL 347 347 347 VAL VAL B . n B 1 348 LEU 348 348 348 LEU LEU B . n B 1 349 GLY 349 349 349 GLY GLY B . n B 1 350 ARG 350 350 350 ARG ARG B . n B 1 351 LEU 351 351 351 LEU LEU B . n B 1 352 ILE 352 352 352 ILE ILE B . n B 1 353 THR 353 353 353 THR THR B . n B 1 354 VAL 354 354 354 VAL VAL B . n B 1 355 ASN 355 355 355 ASN ASN B . n B 1 356 PRO 356 356 356 PRO PRO B . n B 1 357 ILE 357 357 357 ILE ILE B . n B 1 358 VAL 358 358 358 VAL VAL B . n B 1 359 THR 359 359 359 THR THR B . n B 1 360 GLU 360 360 360 GLU GLU B . n B 1 361 LYS 361 361 361 LYS LYS B . n B 1 362 ASP 362 362 362 ASP ASP B . n B 1 363 SER 363 363 363 SER SER B . n B 1 364 PRO 364 364 364 PRO PRO B . n B 1 365 VAL 365 365 365 VAL VAL B . n B 1 366 ASN 366 366 366 ASN ASN B . n B 1 367 ILE 367 367 367 ILE ILE B . n B 1 368 GLU 368 368 368 GLU GLU B . n B 1 369 ALA 369 369 369 ALA ALA B . n B 1 370 GLU 370 370 370 GLU GLU B . n B 1 371 PRO 371 371 371 PRO PRO B . n B 1 372 PRO 372 372 372 PRO PRO B . n B 1 373 PHE 373 373 373 PHE PHE B . n B 1 374 GLY 374 374 374 GLY GLY B . n B 1 375 ASP 375 375 375 ASP ASP B . n B 1 376 SER 376 376 376 SER SER B . n B 1 377 TYR 377 377 377 TYR TYR B . n B 1 378 ILE 378 378 378 ILE ILE B . n B 1 379 ILE 379 379 379 ILE ILE B . n B 1 380 VAL 380 380 380 VAL VAL B . n B 1 381 GLY 381 381 381 GLY GLY B . n B 1 382 VAL 382 382 382 VAL VAL B . n B 1 383 GLU 383 383 383 GLU GLU B . n B 1 384 PRO 384 384 384 PRO PRO B . n B 1 385 GLY 385 385 385 GLY GLY B . n B 1 386 GLN 386 386 386 GLN GLN B . n B 1 387 LEU 387 387 387 LEU LEU B . n B 1 388 LYS 388 388 388 LYS LYS B . n B 1 389 LEU 389 389 389 LEU LEU B . n B 1 390 ASN 390 390 390 ASN ASN B . n B 1 391 TRP 391 391 391 TRP TRP B . n B 1 392 LEU 392 392 392 LEU LEU B . n B 1 393 ARG 393 393 393 ARG ARG B . n B 1 394 PRO 394 394 394 PRO PRO B . n B 1 395 LEU 395 395 395 LEU LEU B . n B 1 396 GLU 396 396 ? ? ? B . n B 1 397 SER 397 397 ? ? ? B . n B 1 398 ARG 398 398 ? ? ? B . n B 1 399 GLY 399 399 ? ? ? B . n B 1 400 PRO 400 400 ? ? ? B . n B 1 401 PHE 401 401 ? ? ? B . n B 1 402 GLU 402 402 ? ? ? B . n B 1 403 GLY 403 403 ? ? ? B . n B 1 404 LYS 404 404 ? ? ? B . n B 1 405 PRO 405 405 ? ? ? B . n B 1 406 ILE 406 406 ? ? ? B . n B 1 407 PRO 407 407 ? ? ? B . n B 1 408 ASN 408 408 ? ? ? B . n B 1 409 PRO 409 409 ? ? ? B . n B 1 410 LEU 410 410 ? ? ? B . n B 1 411 LEU 411 411 ? ? ? B . n B 1 412 GLY 412 412 ? ? ? B . n B 1 413 LEU 413 413 ? ? ? B . n B 1 414 ASP 414 414 ? ? ? B . n B 1 415 SER 415 415 ? ? ? B . n B 1 416 THR 416 416 ? ? ? B . n B 1 417 ARG 417 417 ? ? ? B . n B 1 418 THR 418 418 ? ? ? B . n B 1 419 GLY 419 419 ? ? ? B . n B 1 420 HIS 420 420 ? ? ? B . n B 1 421 HIS 421 421 ? ? ? B . n B 1 422 HIS 422 422 ? ? ? B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 NAG 1 501 501 NAG NAG A . D 3 FUC 2 502 502 FUC FUC A . E 2 NAG 3 503 503 NAG NAG A . F 2 NAG 1 567 567 NAG NAG A . G 2 NAG 2 569 569 NAG NAG A . H 2 NAG 1 501 501 NAG NAG B . I 3 FUC 2 502 502 FUC FUC B . J 2 NAG 3 503 503 NAG NAG B . K 4 BMA 4 504 504 BMA BMA B . L 4 BMA 5 505 505 BMA BMA B . M 4 BMA 6 506 506 BMA BMA B . N 2 NAG 1 567 567 NAG NAG B . O 2 NAG 2 569 569 NAG NAG B . P 5 HOH 1 2001 2001 HOH HOH A . P 5 HOH 2 2002 2002 HOH HOH A . P 5 HOH 3 2003 2003 HOH HOH A . Q 5 HOH 1 2001 2001 HOH HOH B . Q 5 HOH 2 2002 2002 HOH HOH B . Q 5 HOH 3 2003 2003 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 67 A ASN 67 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 153 A ASN 153 ? ASN 'GLYCOSYLATION SITE' 3 B ASN 67 B ASN 67 ? ASN 'GLYCOSYLATION SITE' 4 B ASN 153 B ASN 153 ? ASN 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA monomeric 1 2 author_and_software_defined_assembly PISA monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,C,D,E,F,G,P 2 1 B,H,I,J,K,L,M,N,O,Q # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2015-01-28 2 'Structure model' 1 1 2015-04-08 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Database references' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal BUSTER refinement 2.11.4 ? 1 XDS 'data reduction' . ? 2 SCALA 'data scaling' . ? 3 PHASER phasing . ? 4 # _pdbx_entry_details.entry_id 4UTC _pdbx_entry_details.compound_details ? _pdbx_entry_details.source_details ? _pdbx_entry_details.nonpolymer_details ? _pdbx_entry_details.sequence_details ;THE RESIDUES AFTER W391 DERIVE FROM THE VECTOR. RESIDUES 392 TO 394 COMPLETE THE G STRAND OF ENVELOPE GLYCOPROTEIN DOMAIN III. GB KM087965 ; # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 GLN A 52 ? ? 53.88 75.41 2 1 THR A 76 ? ? 71.70 -2.72 3 1 ASN A 103 ? ? -147.82 27.94 4 1 GLU A 148 ? ? -26.60 -45.41 5 1 ALA A 150 ? ? -30.22 -37.68 6 1 LYS A 157 ? ? -36.30 -39.44 7 1 THR A 176 ? ? -55.07 92.88 8 1 PHE A 193 ? ? 67.54 -16.39 9 1 GLU A 195 ? ? -99.30 56.24 10 1 MET A 201 ? ? -92.02 -85.36 11 1 GLU A 202 ? ? -118.03 -95.41 12 1 ASP A 215 ? ? -101.13 49.62 13 1 SER A 229 ? ? -140.45 -47.67 14 1 GLN B 52 ? ? 43.36 74.46 15 1 THR B 76 ? ? 69.99 -1.83 16 1 GLU B 84 ? ? -35.77 -33.78 17 1 ASN B 103 ? ? -144.93 27.57 18 1 GLU B 147 ? ? -37.33 115.14 19 1 GLU B 148 ? ? -26.98 -47.66 20 1 THR B 176 ? ? -57.58 95.04 21 1 LEU B 199 ? ? -69.45 96.06 22 1 MET B 201 ? ? -92.46 -91.06 23 1 GLU B 202 ? ? -107.16 -93.13 24 1 SER B 274 ? ? -152.07 65.97 25 1 SER B 331 ? ? -39.79 132.91 26 1 ASP B 341 ? ? -68.53 -171.74 27 1 LYS B 344 ? ? 104.05 1.23 28 1 ARG B 345 ? ? -49.51 -91.84 29 1 LEU B 348 ? ? -121.68 -69.93 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A ARG 288 ? CG ? A ARG 288 CG 2 1 Y 1 A ARG 288 ? CD ? A ARG 288 CD 3 1 Y 1 A ARG 288 ? NE ? A ARG 288 NE 4 1 Y 1 A ARG 288 ? CZ ? A ARG 288 CZ 5 1 Y 1 A ARG 288 ? NH1 ? A ARG 288 NH1 6 1 Y 1 A ARG 288 ? NH2 ? A ARG 288 NH2 7 1 Y 1 A LEU 395 ? CG ? A LEU 395 CG 8 1 Y 1 A LEU 395 ? CD1 ? A LEU 395 CD1 9 1 Y 1 A LEU 395 ? CD2 ? A LEU 395 CD2 10 1 Y 1 B LEU 395 ? CG ? B LEU 395 CG 11 1 Y 1 B LEU 395 ? CD1 ? B LEU 395 CD1 12 1 Y 1 B LEU 395 ? CD2 ? B LEU 395 CD2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLY 190 ? A GLY 190 2 1 Y 1 A LEU 191 ? A LEU 191 3 1 Y 1 A THR 280 ? A THR 280 4 1 Y 1 A GLY 281 ? A GLY 281 5 1 Y 1 A GLU 396 ? A GLU 396 6 1 Y 1 A SER 397 ? A SER 397 7 1 Y 1 A ARG 398 ? A ARG 398 8 1 Y 1 A GLY 399 ? A GLY 399 9 1 Y 1 A PRO 400 ? A PRO 400 10 1 Y 1 A PHE 401 ? A PHE 401 11 1 Y 1 A GLU 402 ? A GLU 402 12 1 Y 1 A GLY 403 ? A GLY 403 13 1 Y 1 A LYS 404 ? A LYS 404 14 1 Y 1 A PRO 405 ? A PRO 405 15 1 Y 1 A ILE 406 ? A ILE 406 16 1 Y 1 A PRO 407 ? A PRO 407 17 1 Y 1 A ASN 408 ? A ASN 408 18 1 Y 1 A PRO 409 ? A PRO 409 19 1 Y 1 A LEU 410 ? A LEU 410 20 1 Y 1 A LEU 411 ? A LEU 411 21 1 Y 1 A GLY 412 ? A GLY 412 22 1 Y 1 A LEU 413 ? A LEU 413 23 1 Y 1 A ASP 414 ? A ASP 414 24 1 Y 1 A SER 415 ? A SER 415 25 1 Y 1 A THR 416 ? A THR 416 26 1 Y 1 A ARG 417 ? A ARG 417 27 1 Y 1 A THR 418 ? A THR 418 28 1 Y 1 A GLY 419 ? A GLY 419 29 1 Y 1 A HIS 420 ? A HIS 420 30 1 Y 1 A HIS 421 ? A HIS 421 31 1 Y 1 A HIS 422 ? A HIS 422 32 1 Y 1 B VAL 15 ? B VAL 15 33 1 Y 1 B SER 16 ? B SER 16 34 1 Y 1 B GLY 17 ? B GLY 17 35 1 Y 1 B GLY 18 ? B GLY 18 36 1 Y 1 B SER 19 ? B SER 19 37 1 Y 1 B GLU 396 ? B GLU 396 38 1 Y 1 B SER 397 ? B SER 397 39 1 Y 1 B ARG 398 ? B ARG 398 40 1 Y 1 B GLY 399 ? B GLY 399 41 1 Y 1 B PRO 400 ? B PRO 400 42 1 Y 1 B PHE 401 ? B PHE 401 43 1 Y 1 B GLU 402 ? B GLU 402 44 1 Y 1 B GLY 403 ? B GLY 403 45 1 Y 1 B LYS 404 ? B LYS 404 46 1 Y 1 B PRO 405 ? B PRO 405 47 1 Y 1 B ILE 406 ? B ILE 406 48 1 Y 1 B PRO 407 ? B PRO 407 49 1 Y 1 B ASN 408 ? B ASN 408 50 1 Y 1 B PRO 409 ? B PRO 409 51 1 Y 1 B LEU 410 ? B LEU 410 52 1 Y 1 B LEU 411 ? B LEU 411 53 1 Y 1 B GLY 412 ? B GLY 412 54 1 Y 1 B LEU 413 ? B LEU 413 55 1 Y 1 B ASP 414 ? B ASP 414 56 1 Y 1 B SER 415 ? B SER 415 57 1 Y 1 B THR 416 ? B THR 416 58 1 Y 1 B ARG 417 ? B ARG 417 59 1 Y 1 B THR 418 ? B THR 418 60 1 Y 1 B GLY 419 ? B GLY 419 61 1 Y 1 B HIS 420 ? B HIS 420 62 1 Y 1 B HIS 421 ? B HIS 421 63 1 Y 1 B HIS 422 ? B HIS 422 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 ALPHA-L-FUCOSE FUC 4 BETA-D-MANNOSE BMA 5 water HOH #