data_4IRS # _entry.id 4IRS # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4IRS RCSB RCSB077127 WWPDB D_1000077127 # _pdbx_database_related.db_name PDB _pdbx_database_related.db_id 4IRJ _pdbx_database_related.details . _pdbx_database_related.content_type unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 4IRS _pdbx_database_status.recvd_initial_deposition_date 2013-01-15 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Nemcovic, M.' 1 'Zajonc, D.M.' 2 # _citation.id primary _citation.title 'Enhanced TCR footprint by a novel glycolipid increases NKT-dependent tumor protection.' _citation.journal_abbrev J.Immunol. _citation.journal_volume 191 _citation.page_first 2916 _citation.page_last 2925 _citation.year 2013 _citation.journal_id_ASTM JOIMA3 _citation.country US _citation.journal_id_ISSN 0022-1767 _citation.journal_id_CSD 0952 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 23960235 _citation.pdbx_database_id_DOI 10.4049/jimmunol.1203134 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Aspeslagh, S.' 1 primary 'Nemcovic, M.' 2 primary 'Pauwels, N.' 3 primary 'Venken, K.' 4 primary 'Wang, J.' 5 primary 'Van Calenbergh, S.' 6 primary 'Zajonc, D.M.' 7 primary 'Elewaut, D.' 8 # _cell.entry_id 4IRS _cell.length_a 78.970 _cell.length_b 191.400 _cell.length_c 151.220 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? # _symmetry.entry_id 4IRS _symmetry.space_group_name_H-M 'C 2 2 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 20 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Antigen-presenting glycoprotein CD1d1' 32632.668 1 ? ? 'UNP residues 19-298' ? 2 polymer man Beta-2-microglobulin 11660.350 1 ? ? ? ? 3 polymer man 'Valpha14 (mouse variable domain, human constant domain)' 23055.621 1 ? ? ? ? 4 polymer man 'Vbeta8.2 (mouse variable domain, human constant domain)' 27026.998 1 ? ? ? ? 5 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 5 ? ? ? ? 6 non-polymer man BETA-L-FUCOSE 164.156 1 ? ? ? ? 7 non-polymer syn 'N-[(2S,3S,4R)-3,4-dihydroxy-1-{[6-O-(pyridin-4-ylcarbamoyl)-alpha-D-galactopyranosyl]oxy}octadecan-2-yl]hexacosanamide' 978.431 1 ? ? ? ? 8 water nat water 18.015 112 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;SEAQQKNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRD IQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATV QMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPSSAHGHRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPN ADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYWHHHHHH ; ;SEAQQKNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRD IQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATV QMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPSSAHGHRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPN ADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYWHHHHHH ; A ? 2 'polypeptide(L)' no no ;IQKTPQIQVYSRHPPENGKPNILNCYVTQFHPPHIEIQMLKNGKKIPKVEMSDMSFSKDWSFYILAHTEFTPTETDTYAC RVKHASMAEPKTVYWDRDM ; ;IQKTPQIQVYSRHPPENGKPNILNCYVTQFHPPHIEIQMLKNGKKIPKVEMSDMSFSKDWSFYILAHTEFTPTETDTYAC RVKHASMAEPKTVYWDRDM ; B ? 3 'polypeptide(L)' no no ;MKTQVEQSPQSLVVRQGENCVLQCNYSVTPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITA TLLDDTATYICVVGDRGSALGRLHFGAGTQLIVIPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYIT DKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESS ; ;MKTQVEQSPQSLVVRQGENCVLQCNYSVTPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITA TLLDDTATYICVVGDRGSALGRLHFGAGTQLIVIPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYIT DKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESS ; C ? 4 'polypeptide(L)' no no ;MEAAVTQSPRNKVAVTGGKVTLSCNQTNNHNNMYWYRQDTGHGLRLIHYSYGAGSTEKGDIPDGYKASRPSQENFSLILE LATPSQTSVYFCASGDEGYTQYFGPGTRLLVLEDLRNVTPPKVSLFEPSKAEISHTQKATLVCLATGFYPDHVELSWWVN GKEVHSGVCTDPQPLKEQPALNDSRYSLSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGR A ; ;MEAAVTQSPRNKVAVTGGKVTLSCNQTNNHNNMYWYRQDTGHGLRLIHYSYGAGSTEKGDIPDGYKASRPSQENFSLILE LATPSQTSVYFCASGDEGYTQYFGPGTRLLVLEDLRNVTPPKVSLFEPSKAEISHTQKATLVCLATGFYPDHVELSWWVN GKEVHSGVCTDPQPLKEQPALNDSRYSLSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGR A ; D ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 SER n 1 2 GLU n 1 3 ALA n 1 4 GLN n 1 5 GLN n 1 6 LYS n 1 7 ASN n 1 8 TYR n 1 9 THR n 1 10 PHE n 1 11 ARG n 1 12 CYS n 1 13 LEU n 1 14 GLN n 1 15 MET n 1 16 SER n 1 17 SER n 1 18 PHE n 1 19 ALA n 1 20 ASN n 1 21 ARG n 1 22 SER n 1 23 TRP n 1 24 SER n 1 25 ARG n 1 26 THR n 1 27 ASP n 1 28 SER n 1 29 VAL n 1 30 VAL n 1 31 TRP n 1 32 LEU n 1 33 GLY n 1 34 ASP n 1 35 LEU n 1 36 GLN n 1 37 THR n 1 38 HIS n 1 39 ARG n 1 40 TRP n 1 41 SER n 1 42 ASN n 1 43 ASP n 1 44 SER n 1 45 ALA n 1 46 THR n 1 47 ILE n 1 48 SER n 1 49 PHE n 1 50 THR n 1 51 LYS n 1 52 PRO n 1 53 TRP n 1 54 SER n 1 55 GLN n 1 56 GLY n 1 57 LYS n 1 58 LEU n 1 59 SER n 1 60 ASN n 1 61 GLN n 1 62 GLN n 1 63 TRP n 1 64 GLU n 1 65 LYS n 1 66 LEU n 1 67 GLN n 1 68 HIS n 1 69 MET n 1 70 PHE n 1 71 GLN n 1 72 VAL n 1 73 TYR n 1 74 ARG n 1 75 VAL n 1 76 SER n 1 77 PHE n 1 78 THR n 1 79 ARG n 1 80 ASP n 1 81 ILE n 1 82 GLN n 1 83 GLU n 1 84 LEU n 1 85 VAL n 1 86 LYS n 1 87 MET n 1 88 MET n 1 89 SER n 1 90 PRO n 1 91 LYS n 1 92 GLU n 1 93 ASP n 1 94 TYR n 1 95 PRO n 1 96 ILE n 1 97 GLU n 1 98 ILE n 1 99 GLN n 1 100 LEU n 1 101 SER n 1 102 ALA n 1 103 GLY n 1 104 CYS n 1 105 GLU n 1 106 MET n 1 107 TYR n 1 108 PRO n 1 109 GLY n 1 110 ASN n 1 111 ALA n 1 112 SER n 1 113 GLU n 1 114 SER n 1 115 PHE n 1 116 LEU n 1 117 HIS n 1 118 VAL n 1 119 ALA n 1 120 PHE n 1 121 GLN n 1 122 GLY n 1 123 LYS n 1 124 TYR n 1 125 VAL n 1 126 VAL n 1 127 ARG n 1 128 PHE n 1 129 TRP n 1 130 GLY n 1 131 THR n 1 132 SER n 1 133 TRP n 1 134 GLN n 1 135 THR n 1 136 VAL n 1 137 PRO n 1 138 GLY n 1 139 ALA n 1 140 PRO n 1 141 SER n 1 142 TRP n 1 143 LEU n 1 144 ASP n 1 145 LEU n 1 146 PRO n 1 147 ILE n 1 148 LYS n 1 149 VAL n 1 150 LEU n 1 151 ASN n 1 152 ALA n 1 153 ASP n 1 154 GLN n 1 155 GLY n 1 156 THR n 1 157 SER n 1 158 ALA n 1 159 THR n 1 160 VAL n 1 161 GLN n 1 162 MET n 1 163 LEU n 1 164 LEU n 1 165 ASN n 1 166 ASP n 1 167 THR n 1 168 CYS n 1 169 PRO n 1 170 LEU n 1 171 PHE n 1 172 VAL n 1 173 ARG n 1 174 GLY n 1 175 LEU n 1 176 LEU n 1 177 GLU n 1 178 ALA n 1 179 GLY n 1 180 LYS n 1 181 SER n 1 182 ASP n 1 183 LEU n 1 184 GLU n 1 185 LYS n 1 186 GLN n 1 187 GLU n 1 188 LYS n 1 189 PRO n 1 190 VAL n 1 191 ALA n 1 192 TRP n 1 193 LEU n 1 194 SER n 1 195 SER n 1 196 VAL n 1 197 PRO n 1 198 SER n 1 199 SER n 1 200 ALA n 1 201 HIS n 1 202 GLY n 1 203 HIS n 1 204 ARG n 1 205 GLN n 1 206 LEU n 1 207 VAL n 1 208 CYS n 1 209 HIS n 1 210 VAL n 1 211 SER n 1 212 GLY n 1 213 PHE n 1 214 TYR n 1 215 PRO n 1 216 LYS n 1 217 PRO n 1 218 VAL n 1 219 TRP n 1 220 VAL n 1 221 MET n 1 222 TRP n 1 223 MET n 1 224 ARG n 1 225 GLY n 1 226 ASP n 1 227 GLN n 1 228 GLU n 1 229 GLN n 1 230 GLN n 1 231 GLY n 1 232 THR n 1 233 HIS n 1 234 ARG n 1 235 GLY n 1 236 ASP n 1 237 PHE n 1 238 LEU n 1 239 PRO n 1 240 ASN n 1 241 ALA n 1 242 ASP n 1 243 GLU n 1 244 THR n 1 245 TRP n 1 246 TYR n 1 247 LEU n 1 248 GLN n 1 249 ALA n 1 250 THR n 1 251 LEU n 1 252 ASP n 1 253 VAL n 1 254 GLU n 1 255 ALA n 1 256 GLY n 1 257 GLU n 1 258 GLU n 1 259 ALA n 1 260 GLY n 1 261 LEU n 1 262 ALA n 1 263 CYS n 1 264 ARG n 1 265 VAL n 1 266 LYS n 1 267 HIS n 1 268 SER n 1 269 SER n 1 270 LEU n 1 271 GLY n 1 272 GLY n 1 273 GLN n 1 274 ASP n 1 275 ILE n 1 276 ILE n 1 277 LEU n 1 278 TYR n 1 279 TRP n 1 280 HIS n 1 281 HIS n 1 282 HIS n 1 283 HIS n 1 284 HIS n 1 285 HIS n 2 1 ILE n 2 2 GLN n 2 3 LYS n 2 4 THR n 2 5 PRO n 2 6 GLN n 2 7 ILE n 2 8 GLN n 2 9 VAL n 2 10 TYR n 2 11 SER n 2 12 ARG n 2 13 HIS n 2 14 PRO n 2 15 PRO n 2 16 GLU n 2 17 ASN n 2 18 GLY n 2 19 LYS n 2 20 PRO n 2 21 ASN n 2 22 ILE n 2 23 LEU n 2 24 ASN n 2 25 CYS n 2 26 TYR n 2 27 VAL n 2 28 THR n 2 29 GLN n 2 30 PHE n 2 31 HIS n 2 32 PRO n 2 33 PRO n 2 34 HIS n 2 35 ILE n 2 36 GLU n 2 37 ILE n 2 38 GLN n 2 39 MET n 2 40 LEU n 2 41 LYS n 2 42 ASN n 2 43 GLY n 2 44 LYS n 2 45 LYS n 2 46 ILE n 2 47 PRO n 2 48 LYS n 2 49 VAL n 2 50 GLU n 2 51 MET n 2 52 SER n 2 53 ASP n 2 54 MET n 2 55 SER n 2 56 PHE n 2 57 SER n 2 58 LYS n 2 59 ASP n 2 60 TRP n 2 61 SER n 2 62 PHE n 2 63 TYR n 2 64 ILE n 2 65 LEU n 2 66 ALA n 2 67 HIS n 2 68 THR n 2 69 GLU n 2 70 PHE n 2 71 THR n 2 72 PRO n 2 73 THR n 2 74 GLU n 2 75 THR n 2 76 ASP n 2 77 THR n 2 78 TYR n 2 79 ALA n 2 80 CYS n 2 81 ARG n 2 82 VAL n 2 83 LYS n 2 84 HIS n 2 85 ALA n 2 86 SER n 2 87 MET n 2 88 ALA n 2 89 GLU n 2 90 PRO n 2 91 LYS n 2 92 THR n 2 93 VAL n 2 94 TYR n 2 95 TRP n 2 96 ASP n 2 97 ARG n 2 98 ASP n 2 99 MET n 3 1 MET n 3 2 LYS n 3 3 THR n 3 4 GLN n 3 5 VAL n 3 6 GLU n 3 7 GLN n 3 8 SER n 3 9 PRO n 3 10 GLN n 3 11 SER n 3 12 LEU n 3 13 VAL n 3 14 VAL n 3 15 ARG n 3 16 GLN n 3 17 GLY n 3 18 GLU n 3 19 ASN n 3 20 CYS n 3 21 VAL n 3 22 LEU n 3 23 GLN n 3 24 CYS n 3 25 ASN n 3 26 TYR n 3 27 SER n 3 28 VAL n 3 29 THR n 3 30 PRO n 3 31 ASP n 3 32 ASN n 3 33 HIS n 3 34 LEU n 3 35 ARG n 3 36 TRP n 3 37 PHE n 3 38 LYS n 3 39 GLN n 3 40 ASP n 3 41 THR n 3 42 GLY n 3 43 LYS n 3 44 GLY n 3 45 LEU n 3 46 VAL n 3 47 SER n 3 48 LEU n 3 49 THR n 3 50 VAL n 3 51 LEU n 3 52 VAL n 3 53 ASP n 3 54 GLN n 3 55 LYS n 3 56 ASP n 3 57 LYS n 3 58 THR n 3 59 SER n 3 60 ASN n 3 61 GLY n 3 62 ARG n 3 63 TYR n 3 64 SER n 3 65 ALA n 3 66 THR n 3 67 LEU n 3 68 ASP n 3 69 LYS n 3 70 ASP n 3 71 ALA n 3 72 LYS n 3 73 HIS n 3 74 SER n 3 75 THR n 3 76 LEU n 3 77 HIS n 3 78 ILE n 3 79 THR n 3 80 ALA n 3 81 THR n 3 82 LEU n 3 83 LEU n 3 84 ASP n 3 85 ASP n 3 86 THR n 3 87 ALA n 3 88 THR n 3 89 TYR n 3 90 ILE n 3 91 CYS n 3 92 VAL n 3 93 VAL n 3 94 GLY n 3 95 ASP n 3 96 ARG n 3 97 GLY n 3 98 SER n 3 99 ALA n 3 100 LEU n 3 101 GLY n 3 102 ARG n 3 103 LEU n 3 104 HIS n 3 105 PHE n 3 106 GLY n 3 107 ALA n 3 108 GLY n 3 109 THR n 3 110 GLN n 3 111 LEU n 3 112 ILE n 3 113 VAL n 3 114 ILE n 3 115 PRO n 3 116 ASP n 3 117 ILE n 3 118 GLN n 3 119 ASN n 3 120 PRO n 3 121 ASP n 3 122 PRO n 3 123 ALA n 3 124 VAL n 3 125 TYR n 3 126 GLN n 3 127 LEU n 3 128 ARG n 3 129 ASP n 3 130 SER n 3 131 LYS n 3 132 SER n 3 133 SER n 3 134 ASP n 3 135 LYS n 3 136 SER n 3 137 VAL n 3 138 CYS n 3 139 LEU n 3 140 PHE n 3 141 THR n 3 142 ASP n 3 143 PHE n 3 144 ASP n 3 145 SER n 3 146 GLN n 3 147 THR n 3 148 ASN n 3 149 VAL n 3 150 SER n 3 151 GLN n 3 152 SER n 3 153 LYS n 3 154 ASP n 3 155 SER n 3 156 ASP n 3 157 VAL n 3 158 TYR n 3 159 ILE n 3 160 THR n 3 161 ASP n 3 162 LYS n 3 163 CYS n 3 164 VAL n 3 165 LEU n 3 166 ASP n 3 167 MET n 3 168 ARG n 3 169 SER n 3 170 MET n 3 171 ASP n 3 172 PHE n 3 173 LYS n 3 174 SER n 3 175 ASN n 3 176 SER n 3 177 ALA n 3 178 VAL n 3 179 ALA n 3 180 TRP n 3 181 SER n 3 182 ASN n 3 183 LYS n 3 184 SER n 3 185 ASP n 3 186 PHE n 3 187 ALA n 3 188 CYS n 3 189 ALA n 3 190 ASN n 3 191 ALA n 3 192 PHE n 3 193 ASN n 3 194 ASN n 3 195 SER n 3 196 ILE n 3 197 ILE n 3 198 PRO n 3 199 GLU n 3 200 ASP n 3 201 THR n 3 202 PHE n 3 203 PHE n 3 204 PRO n 3 205 SER n 3 206 PRO n 3 207 GLU n 3 208 SER n 3 209 SER n 4 1 MET n 4 2 GLU n 4 3 ALA n 4 4 ALA n 4 5 VAL n 4 6 THR n 4 7 GLN n 4 8 SER n 4 9 PRO n 4 10 ARG n 4 11 ASN n 4 12 LYS n 4 13 VAL n 4 14 ALA n 4 15 VAL n 4 16 THR n 4 17 GLY n 4 18 GLY n 4 19 LYS n 4 20 VAL n 4 21 THR n 4 22 LEU n 4 23 SER n 4 24 CYS n 4 25 ASN n 4 26 GLN n 4 27 THR n 4 28 ASN n 4 29 ASN n 4 30 HIS n 4 31 ASN n 4 32 ASN n 4 33 MET n 4 34 TYR n 4 35 TRP n 4 36 TYR n 4 37 ARG n 4 38 GLN n 4 39 ASP n 4 40 THR n 4 41 GLY n 4 42 HIS n 4 43 GLY n 4 44 LEU n 4 45 ARG n 4 46 LEU n 4 47 ILE n 4 48 HIS n 4 49 TYR n 4 50 SER n 4 51 TYR n 4 52 GLY n 4 53 ALA n 4 54 GLY n 4 55 SER n 4 56 THR n 4 57 GLU n 4 58 LYS n 4 59 GLY n 4 60 ASP n 4 61 ILE n 4 62 PRO n 4 63 ASP n 4 64 GLY n 4 65 TYR n 4 66 LYS n 4 67 ALA n 4 68 SER n 4 69 ARG n 4 70 PRO n 4 71 SER n 4 72 GLN n 4 73 GLU n 4 74 ASN n 4 75 PHE n 4 76 SER n 4 77 LEU n 4 78 ILE n 4 79 LEU n 4 80 GLU n 4 81 LEU n 4 82 ALA n 4 83 THR n 4 84 PRO n 4 85 SER n 4 86 GLN n 4 87 THR n 4 88 SER n 4 89 VAL n 4 90 TYR n 4 91 PHE n 4 92 CYS n 4 93 ALA n 4 94 SER n 4 95 GLY n 4 96 ASP n 4 97 GLU n 4 98 GLY n 4 99 TYR n 4 100 THR n 4 101 GLN n 4 102 TYR n 4 103 PHE n 4 104 GLY n 4 105 PRO n 4 106 GLY n 4 107 THR n 4 108 ARG n 4 109 LEU n 4 110 LEU n 4 111 VAL n 4 112 LEU n 4 113 GLU n 4 114 ASP n 4 115 LEU n 4 116 ARG n 4 117 ASN n 4 118 VAL n 4 119 THR n 4 120 PRO n 4 121 PRO n 4 122 LYS n 4 123 VAL n 4 124 SER n 4 125 LEU n 4 126 PHE n 4 127 GLU n 4 128 PRO n 4 129 SER n 4 130 LYS n 4 131 ALA n 4 132 GLU n 4 133 ILE n 4 134 SER n 4 135 HIS n 4 136 THR n 4 137 GLN n 4 138 LYS n 4 139 ALA n 4 140 THR n 4 141 LEU n 4 142 VAL n 4 143 CYS n 4 144 LEU n 4 145 ALA n 4 146 THR n 4 147 GLY n 4 148 PHE n 4 149 TYR n 4 150 PRO n 4 151 ASP n 4 152 HIS n 4 153 VAL n 4 154 GLU n 4 155 LEU n 4 156 SER n 4 157 TRP n 4 158 TRP n 4 159 VAL n 4 160 ASN n 4 161 GLY n 4 162 LYS n 4 163 GLU n 4 164 VAL n 4 165 HIS n 4 166 SER n 4 167 GLY n 4 168 VAL n 4 169 CYS n 4 170 THR n 4 171 ASP n 4 172 PRO n 4 173 GLN n 4 174 PRO n 4 175 LEU n 4 176 LYS n 4 177 GLU n 4 178 GLN n 4 179 PRO n 4 180 ALA n 4 181 LEU n 4 182 ASN n 4 183 ASP n 4 184 SER n 4 185 ARG n 4 186 TYR n 4 187 SER n 4 188 LEU n 4 189 SER n 4 190 SER n 4 191 ARG n 4 192 LEU n 4 193 ARG n 4 194 VAL n 4 195 SER n 4 196 ALA n 4 197 THR n 4 198 PHE n 4 199 TRP n 4 200 GLN n 4 201 ASN n 4 202 PRO n 4 203 ARG n 4 204 ASN n 4 205 HIS n 4 206 PHE n 4 207 ARG n 4 208 CYS n 4 209 GLN n 4 210 VAL n 4 211 GLN n 4 212 PHE n 4 213 TYR n 4 214 GLY n 4 215 LEU n 4 216 SER n 4 217 GLU n 4 218 ASN n 4 219 ASP n 4 220 GLU n 4 221 TRP n 4 222 THR n 4 223 GLN n 4 224 ASP n 4 225 ARG n 4 226 ALA n 4 227 LYS n 4 228 PRO n 4 229 VAL n 4 230 THR n 4 231 GLN n 4 232 ILE n 4 233 VAL n 4 234 SER n 4 235 ALA n 4 236 GLU n 4 237 ALA n 4 238 TRP n 4 239 GLY n 4 240 ARG n 4 241 ALA n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample ? ? ? mouse ? 'Cd1.1, CD1d, Cd1d1' ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? 'fall armyworm' 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? Sf9 ? ? ? ? ? ? ? 'baculovirus transfer system' ? ? ? pBACp10pH ? ? 2 1 sample ? ? ? mouse ? 'B2m, beta-2-microglobulin' ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? 'fall armyworm' 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? Sf9 ? ? ? ? ? ? ? 'baculovirus transfer system' ? ? ? pBACp10pH ? ? 3 1 sample ? ? ? 'mouse, human' ? 'Valpha14 (mouse variable domain, human constant domain)' ? ? ? ? ? ? 'Mus musculus, Homo sapiens' '10090, 9606' ? ? ? ? ? ? ? ? 'Escherichia coli' 469008 ? ? ? ? ? ? BL21DE3 ? ? ? ? ? ? ? plasmid ? ? ? pET22b ? ? 4 1 sample ? ? ? 'mouse, human' ? 'Vbeta8.2 (mouse variable domain, human constant domain)' ? ? ? ? ? ? 'Mus musculus, Homo sapiens' '10090, 9606' ? ? ? ? ? ? ? ? 'Escherichia coli' 469008 ? ? ? ? ? ? BL21DE3 ? ? ? ? ? ? ? plasmid ? ? ? pET30a ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin _struct_ref.pdbx_db_isoform 1 UNP CD1D1_MOUSE P11609 1 ;SEAQQKNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRD IQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATV QMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPSSADGHRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPN ADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW ; 19 ? 2 UNP B2MG_MOUSE P01887 2 ;IQKTPQIQVYSRHPPENGKPNILNCYVTQFHPPHIEIQMLKNGKKIPKVEMSDMSFSKDWSFYILAHTEFTPTETDTYAC RVKHASMAEPKTVYWDRDM ; 21 ? 3 PDB 4IRS 4IRS 3 ;MKTQVEQSPQSLVVRQGENCVLQCNYSVTPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITA TLLDDTATYICVVGDRGSALGRLHFGAGTQLIVIPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYIT DKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESS ; ? ? 4 PDB 4IRS 4IRS 4 ;MEAAVTQSPRNKVAVTGGKVTLSCNQTNNHNNMYWYRQDTGHGLRLIHYSYGAGSTEKGDIPDGYKASRPSQENFSLILE LATPSQTSVYFCASGDEGYTQYFGPGTRLLVLEDLRNVTPPKVSLFEPSKAEISHTQKATLVCLATGFYPDHVELSWWVN GKEVHSGVCTDPQPLKEQPALNDSRYSLSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGR A ; ? ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4IRS A 1 ? 279 ? P11609 19 ? 297 ? 1 279 2 2 4IRS B 1 ? 99 ? P01887 21 ? 119 ? 1 99 3 3 4IRS C 1 ? 209 ? 4IRS -1 ? 207 ? -1 207 4 4 4IRS D 1 ? 241 ? 4IRS 0 ? 240 ? 0 240 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 4IRS HIS A 201 ? UNP P11609 ASP 219 CONFLICT 201 1 1 4IRS HIS A 280 ? UNP P11609 ? ? 'EXPRESSION TAG' 280 2 1 4IRS HIS A 281 ? UNP P11609 ? ? 'EXPRESSION TAG' 281 3 1 4IRS HIS A 282 ? UNP P11609 ? ? 'EXPRESSION TAG' 282 4 1 4IRS HIS A 283 ? UNP P11609 ? ? 'EXPRESSION TAG' 283 5 1 4IRS HIS A 284 ? UNP P11609 ? ? 'EXPRESSION TAG' 284 6 1 4IRS HIS A 285 ? UNP P11609 ? ? 'EXPRESSION TAG' 285 7 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight 1LA non-polymer . 'N-[(2S,3S,4R)-3,4-dihydroxy-1-{[6-O-(pyridin-4-ylcarbamoyl)-alpha-D-galactopyranosyl]oxy}octadecan-2-yl]hexacosanamide' ? 'C56 H103 N3 O10' 978.431 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FUL L-saccharide . BETA-L-FUCOSE 6-DEOXY-BETA-L-GALACTOSE 'C6 H12 O5' 164.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 4IRS _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 3.03 _exptl_crystal.density_percent_sol 59.37 _exptl_crystal.description ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.temp 295.5 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 7.5 _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details '20% polyethylene glycol 4000, 0.2M di-ammonium hydrogen citrate, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 295.5K' # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector PIXEL _diffrn_detector.type 'PSI PILATUS 6M' _diffrn_detector.pdbx_collection_date 2012-01-01 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'Curved crystal' _diffrn_radiation.pdbx_diffrn_protocol MAD _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.979 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'SSRL BEAMLINE BL11-1' _diffrn_source.pdbx_synchrotron_site SSRL _diffrn_source.pdbx_synchrotron_beamline BL11-1 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.979 # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 4IRS _reflns.observed_criterion_sigma_I 0 _reflns.observed_criterion_sigma_F 0 _reflns.d_resolution_low 59.33 _reflns.d_resolution_high 2.8 _reflns.number_obs 26546 _reflns.number_all 28024 _reflns.percent_possible_obs 98.1 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI ? _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy ? # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 2.8 _reflns_shell.d_res_low 2.95 _reflns_shell.percent_possible_all 100 _reflns_shell.Rmerge_I_obs ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs ? _reflns_shell.pdbx_redundancy ? # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 4IRS _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 26546 _refine.ls_number_reflns_all 28024 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F . _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 59.33 _refine.ls_d_res_high 2.80 _refine.ls_percent_reflns_obs 97.57 _refine.ls_R_factor_obs 0.19250 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.19000 _refine.ls_R_factor_R_free 0.23915 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.1 _refine.ls_number_reflns_R_free 1415 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.931 _refine.correlation_coeff_Fo_to_Fc_free 0.890 _refine.B_iso_mean 36.976 _refine.aniso_B[1][1] 0.12 _refine.aniso_B[2][2] 0.02 _refine.aniso_B[3][3] -0.14 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] -0.00 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT' _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 3.890 _refine.pdbx_overall_ESU_R_Free 0.343 _refine.overall_SU_ML 0.234 _refine.pdbx_overall_phase_error ? _refine.overall_SU_B 11.697 _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6343 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 149 _refine_hist.number_atoms_solvent 112 _refine_hist.number_atoms_total 6604 _refine_hist.d_res_high 2.80 _refine_hist.d_res_low 59.33 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.010 0.022 ? 6673 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.243 1.953 ? 9086 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 5.869 5.000 ? 801 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 36.371 24.416 ? 308 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 15.703 15.000 ? 1024 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 15.908 15.000 ? 33 'X-RAY DIFFRACTION' ? r_chiral_restr 0.076 0.200 ? 997 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.005 0.021 ? 5092 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_scbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_scangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.800 _refine_ls_shell.d_res_low 2.873 _refine_ls_shell.number_reflns_R_work 1834 _refine_ls_shell.R_factor_R_work 0.270 _refine_ls_shell.percent_reflns_obs 98.82 _refine_ls_shell.R_factor_R_free 0.348 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 99 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? # _struct.entry_id 4IRS _struct.title 'Structure of the mouse CD1d-PyrC-alpha-GalCer-iNKT TCR complex' _struct.pdbx_descriptor ;Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, Valpha14 (mouse variable domain, human constant domain), Vbeta8.2 (mouse variable domain, human constant domain) ; _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 4IRS _struct_keywords.pdbx_keywords 'IMMUNE SYSTEM' _struct_keywords.text 'antigen presentation, glycolipid, NKT cells, IMMUNE SYSTEM' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 5 ? G N N 5 ? H N N 5 ? I N N 5 ? J N N 6 ? K N N 7 ? L N N 8 ? M N N 8 ? N N N 8 ? O N N 8 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 SER A 59 ? SER A 89 ? SER A 59 SER A 89 1 ? 31 HELX_P HELX_P2 2 PRO A 140 ? TRP A 142 ? PRO A 140 TRP A 142 5 ? 3 HELX_P HELX_P3 3 LEU A 143 ? ASN A 151 ? LEU A 143 ASN A 151 1 ? 9 HELX_P HELX_P4 4 ASP A 153 ? ASP A 166 ? ASP A 153 ASP A 166 1 ? 14 HELX_P HELX_P5 5 ASP A 166 ? GLY A 179 ? ASP A 166 GLY A 179 1 ? 14 HELX_P HELX_P6 6 GLY A 179 ? GLU A 184 ? GLY A 179 GLU A 184 1 ? 6 HELX_P HELX_P7 7 HIS A 267 ? GLY A 271 ? HIS A 267 GLY A 271 5 ? 5 HELX_P HELX_P8 8 LEU C 82 ? THR C 86 ? LEU C 80 THR C 84 5 ? 5 HELX_P HELX_P9 9 ALA C 187 ? PHE C 192 ? ALA C 185 PHE C 190 1 ? 6 HELX_P HELX_P10 10 THR D 83 ? THR D 87 ? THR D 82 THR D 86 5 ? 5 HELX_P HELX_P11 11 SER D 129 ? GLN D 137 ? SER D 128 GLN D 136 1 ? 9 HELX_P HELX_P12 12 ALA D 196 ? GLN D 200 ? ALA D 195 GLN D 199 1 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 104 SG ? ? ? 1_555 A CYS 168 SG ? ? A CYS 104 A CYS 168 1_555 ? ? ? ? ? ? ? 2.100 ? disulf2 disulf ? ? A CYS 208 SG ? ? ? 1_555 A CYS 263 SG ? ? A CYS 208 A CYS 263 1_555 ? ? ? ? ? ? ? 2.033 ? disulf3 disulf ? ? B CYS 25 SG ? ? ? 1_555 B CYS 80 SG ? ? B CYS 25 B CYS 80 1_555 ? ? ? ? ? ? ? 2.036 ? disulf4 disulf ? ? C CYS 24 SG ? ? ? 1_555 C CYS 91 SG ? ? C CYS 22 C CYS 89 1_555 ? ? ? ? ? ? ? 2.057 ? disulf5 disulf ? ? C CYS 138 SG ? ? ? 1_555 C CYS 188 SG ? ? C CYS 136 C CYS 186 1_555 ? ? ? ? ? ? ? 2.046 ? disulf6 disulf ? ? C CYS 163 SG ? ? ? 1_555 D CYS 169 SG ? ? C CYS 161 D CYS 168 1_555 ? ? ? ? ? ? ? 2.058 ? disulf7 disulf ? ? D CYS 24 SG ? ? ? 1_555 D CYS 92 SG ? ? D CYS 23 D CYS 91 1_555 ? ? ? ? ? ? ? 2.035 ? disulf8 disulf ? ? D CYS 143 SG ? ? ? 1_555 D CYS 208 SG ? ? D CYS 142 D CYS 207 1_555 ? ? ? ? ? ? ? 2.024 ? covale1 covale ? ? A ASN 165 ND2 ? ? ? 1_555 H NAG . C1 ? ? A ASN 165 A NAG 304 1_555 ? ? ? ? ? ? ? 1.436 ? covale2 covale ? ? A ASN 42 ND2 ? ? ? 1_555 F NAG . C1 ? ? A ASN 42 A NAG 302 1_555 ? ? ? ? ? ? ? 1.437 ? covale3 covale ? ? H NAG . O4 ? ? ? 1_555 I NAG . C1 ? ? A NAG 304 A NAG 305 1_555 ? ? ? ? ? ? ? 1.439 ? covale4 covale ? ? F NAG . O4 ? ? ? 1_555 G NAG . C1 ? ? A NAG 302 A NAG 303 1_555 ? ? ? ? ? ? ? 1.443 ? covale5 covale ? ? H NAG . O6 ? ? ? 1_555 J FUL . C1 ? ? A NAG 304 A FUL 306 1_555 ? ? ? ? ? ? ? 1.451 ? covale6 covale ? ? A ASN 20 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 20 A NAG 301 1_555 ? ? ? ? ? ? ? 1.455 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 SER 89 A . ? SER 89 A PRO 90 A ? PRO 90 A 1 8.63 2 TYR 94 A . ? TYR 94 A PRO 95 A ? PRO 95 A 1 -5.85 3 TYR 214 A . ? TYR 214 A PRO 215 A ? PRO 215 A 1 6.59 4 HIS 31 B . ? HIS 31 B PRO 32 B ? PRO 32 B 1 -2.64 5 SER 8 C . ? SER 6 C PRO 9 C ? PRO 7 C 1 -2.73 6 THR 29 C . ? THR 27 C PRO 30 C ? PRO 28 C 1 -11.90 7 SER 8 D . ? SER 7 D PRO 9 D ? PRO 8 D 1 -2.62 8 TYR 149 D . ? TYR 148 D PRO 150 D ? PRO 149 D 1 -9.11 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 8 ? B ? 4 ? C ? 4 ? D ? 4 ? E ? 4 ? F ? 4 ? G ? 4 ? H ? 5 ? I ? 5 ? J ? 4 ? K ? 8 ? L ? 8 ? M ? 4 ? N ? 6 ? O ? 4 ? P ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel A 4 5 ? anti-parallel A 5 6 ? anti-parallel A 6 7 ? anti-parallel A 7 8 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel C 3 4 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel G 1 2 ? anti-parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel I 1 2 ? parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? anti-parallel J 1 2 ? parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel K 5 6 ? anti-parallel K 6 7 ? anti-parallel K 7 8 ? anti-parallel L 1 2 ? anti-parallel L 2 3 ? anti-parallel L 3 4 ? anti-parallel L 4 5 ? anti-parallel L 5 6 ? anti-parallel L 6 7 ? anti-parallel L 7 8 ? anti-parallel M 1 2 ? anti-parallel M 2 3 ? anti-parallel M 3 4 ? anti-parallel N 1 2 ? parallel N 2 3 ? anti-parallel N 3 4 ? anti-parallel N 4 5 ? anti-parallel N 5 6 ? anti-parallel O 1 2 ? parallel O 2 3 ? anti-parallel O 3 4 ? anti-parallel P 1 2 ? anti-parallel P 2 3 ? anti-parallel P 3 4 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 SER A 48 ? PHE A 49 ? SER A 48 PHE A 49 A 2 LEU A 35 ? TRP A 40 ? LEU A 35 TRP A 40 A 3 SER A 24 ? LEU A 32 ? SER A 24 LEU A 32 A 4 TYR A 8 ? PHE A 18 ? TYR A 8 PHE A 18 A 5 ILE A 96 ? MET A 106 ? ILE A 96 MET A 106 A 6 SER A 112 ? PHE A 120 ? SER A 112 PHE A 120 A 7 LYS A 123 ? TRP A 129 ? LYS A 123 TRP A 129 A 8 SER A 132 ? THR A 135 ? SER A 132 THR A 135 B 1 VAL A 190 ? VAL A 196 ? VAL A 190 VAL A 196 B 2 GLN A 205 ? PHE A 213 ? GLN A 205 PHE A 213 B 3 TRP A 245 ? ASP A 252 ? TRP A 245 ASP A 252 B 4 HIS A 233 ? ARG A 234 ? HIS A 233 ARG A 234 C 1 VAL A 190 ? VAL A 196 ? VAL A 190 VAL A 196 C 2 GLN A 205 ? PHE A 213 ? GLN A 205 PHE A 213 C 3 TRP A 245 ? ASP A 252 ? TRP A 245 ASP A 252 C 4 LEU A 238 ? PRO A 239 ? LEU A 238 PRO A 239 D 1 GLN A 227 ? GLU A 228 ? GLN A 227 GLU A 228 D 2 TRP A 219 ? ARG A 224 ? TRP A 219 ARG A 224 D 3 LEU A 261 ? LYS A 266 ? LEU A 261 LYS A 266 D 4 ILE A 275 ? TYR A 278 ? ILE A 275 TYR A 278 E 1 GLN B 6 ? SER B 11 ? GLN B 6 SER B 11 E 2 ASN B 21 ? PHE B 30 ? ASN B 21 PHE B 30 E 3 PHE B 62 ? PHE B 70 ? PHE B 62 PHE B 70 E 4 GLU B 50 ? MET B 51 ? GLU B 50 MET B 51 F 1 GLN B 6 ? SER B 11 ? GLN B 6 SER B 11 F 2 ASN B 21 ? PHE B 30 ? ASN B 21 PHE B 30 F 3 PHE B 62 ? PHE B 70 ? PHE B 62 PHE B 70 F 4 SER B 55 ? PHE B 56 ? SER B 55 PHE B 56 G 1 LYS B 44 ? LYS B 45 ? LYS B 44 LYS B 45 G 2 GLU B 36 ? LYS B 41 ? GLU B 36 LYS B 41 G 3 TYR B 78 ? LYS B 83 ? TYR B 78 LYS B 83 G 4 LYS B 91 ? TYR B 94 ? LYS B 91 TYR B 94 H 1 VAL C 5 ? SER C 8 ? VAL C 3 SER C 6 H 2 CYS C 20 ? TYR C 26 ? CYS C 18 TYR C 24 H 3 HIS C 73 ? ILE C 78 ? HIS C 71 ILE C 76 H 4 TYR C 63 ? ASP C 68 ? TYR C 61 ASP C 66 H 5 LYS C 55 ? ASN C 60 ? LYS C 53 ASN C 58 I 1 SER C 11 ? ARG C 15 ? SER C 9 ARG C 13 I 2 THR C 109 ? ILE C 114 ? THR C 107 ILE C 112 I 3 ALA C 87 ? GLY C 94 ? ALA C 85 GLY C 92 I 4 HIS C 33 ? GLN C 39 ? HIS C 31 GLN C 37 I 5 VAL C 46 ? LEU C 51 ? VAL C 44 LEU C 49 J 1 SER C 11 ? ARG C 15 ? SER C 9 ARG C 13 J 2 THR C 109 ? ILE C 114 ? THR C 107 ILE C 112 J 3 ALA C 87 ? GLY C 94 ? ALA C 85 GLY C 92 J 4 LEU C 103 ? PHE C 105 ? LEU C 101 PHE C 103 K 1 TYR C 158 ? ILE C 159 ? TYR C 156 ILE C 157 K 2 PHE C 172 ? TRP C 180 ? PHE C 170 TRP C 178 K 3 SER C 136 ? THR C 141 ? SER C 134 THR C 139 K 4 ALA C 123 ? ASP C 129 ? ALA C 121 ASP C 127 K 5 LYS D 122 ? GLU D 127 ? LYS D 121 GLU D 126 K 6 LYS D 138 ? PHE D 148 ? LYS D 137 PHE D 147 K 7 TYR D 186 ? SER D 195 ? TYR D 185 SER D 194 K 8 VAL D 168 ? THR D 170 ? VAL D 167 THR D 169 L 1 CYS C 163 ? MET C 167 ? CYS C 161 MET C 165 L 2 PHE C 172 ? TRP C 180 ? PHE C 170 TRP C 178 L 3 SER C 136 ? THR C 141 ? SER C 134 THR C 139 L 4 ALA C 123 ? ASP C 129 ? ALA C 121 ASP C 127 L 5 LYS D 122 ? GLU D 127 ? LYS D 121 GLU D 126 L 6 LYS D 138 ? PHE D 148 ? LYS D 137 PHE D 147 L 7 TYR D 186 ? SER D 195 ? TYR D 185 SER D 194 L 8 LEU D 175 ? LYS D 176 ? LEU D 174 LYS D 175 M 1 VAL D 5 ? SER D 8 ? VAL D 4 SER D 7 M 2 VAL D 20 ? GLN D 26 ? VAL D 19 GLN D 25 M 3 ASN D 74 ? LEU D 79 ? ASN D 73 LEU D 78 M 4 LYS D 66 ? SER D 68 ? LYS D 65 SER D 67 N 1 ASN D 11 ? VAL D 15 ? ASN D 10 VAL D 14 N 2 THR D 107 ? LEU D 112 ? THR D 106 LEU D 111 N 3 SER D 88 ? GLY D 95 ? SER D 87 GLY D 94 N 4 ASN D 32 ? GLN D 38 ? ASN D 31 GLN D 37 N 5 ARG D 45 ? SER D 50 ? ARG D 44 SER D 49 N 6 GLU D 57 ? LYS D 58 ? GLU D 56 LYS D 57 O 1 ASN D 11 ? VAL D 15 ? ASN D 10 VAL D 14 O 2 THR D 107 ? LEU D 112 ? THR D 106 LEU D 111 O 3 SER D 88 ? GLY D 95 ? SER D 87 GLY D 94 O 4 TYR D 102 ? PHE D 103 ? TYR D 101 PHE D 102 P 1 LYS D 162 ? VAL D 164 ? LYS D 161 VAL D 163 P 2 VAL D 153 ? VAL D 159 ? VAL D 152 VAL D 158 P 3 HIS D 205 ? PHE D 212 ? HIS D 204 PHE D 211 P 4 GLN D 231 ? TRP D 238 ? GLN D 230 TRP D 237 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 O SER A 48 ? O SER A 48 N ARG A 39 ? N ARG A 39 A 2 3 O TRP A 40 ? O TRP A 40 N SER A 28 ? N SER A 28 A 3 4 O TRP A 31 ? O TRP A 31 N ARG A 11 ? N ARG A 11 A 4 5 N CYS A 12 ? N CYS A 12 O ALA A 102 ? O ALA A 102 A 5 6 N GLN A 99 ? N GLN A 99 O ALA A 119 ? O ALA A 119 A 6 7 N VAL A 118 ? N VAL A 118 O VAL A 126 ? O VAL A 126 A 7 8 N TRP A 129 ? N TRP A 129 O SER A 132 ? O SER A 132 B 1 2 N VAL A 196 ? N VAL A 196 O GLN A 205 ? O GLN A 205 B 2 3 N LEU A 206 ? N LEU A 206 O LEU A 251 ? O LEU A 251 B 3 4 O THR A 250 ? O THR A 250 N HIS A 233 ? N HIS A 233 C 1 2 N VAL A 196 ? N VAL A 196 O GLN A 205 ? O GLN A 205 C 2 3 N LEU A 206 ? N LEU A 206 O LEU A 251 ? O LEU A 251 C 3 4 O TYR A 246 ? O TYR A 246 N LEU A 238 ? N LEU A 238 D 1 2 O GLN A 227 ? O GLN A 227 N ARG A 224 ? N ARG A 224 D 2 3 N TRP A 219 ? N TRP A 219 O LYS A 266 ? O LYS A 266 D 3 4 N VAL A 265 ? N VAL A 265 O ILE A 275 ? O ILE A 275 E 1 2 N TYR B 10 ? N TYR B 10 O ASN B 24 ? O ASN B 24 E 2 3 N CYS B 25 ? N CYS B 25 O ALA B 66 ? O ALA B 66 E 3 4 O HIS B 67 ? O HIS B 67 N GLU B 50 ? N GLU B 50 F 1 2 N TYR B 10 ? N TYR B 10 O ASN B 24 ? O ASN B 24 F 2 3 N CYS B 25 ? N CYS B 25 O ALA B 66 ? O ALA B 66 F 3 4 O TYR B 63 ? O TYR B 63 N SER B 55 ? N SER B 55 G 1 2 O LYS B 44 ? O LYS B 44 N LYS B 41 ? N LYS B 41 G 2 3 N LEU B 40 ? N LEU B 40 O ALA B 79 ? O ALA B 79 G 3 4 N VAL B 82 ? N VAL B 82 O LYS B 91 ? O LYS B 91 H 1 2 N GLU C 6 ? N GLU C 4 O ASN C 25 ? O ASN C 23 H 2 3 N CYS C 24 ? N CYS C 22 O SER C 74 ? O SER C 72 H 3 4 O HIS C 77 ? O HIS C 75 N SER C 64 ? N SER C 62 H 4 5 O TYR C 63 ? O TYR C 61 N ASN C 60 ? N ASN C 58 I 1 2 N VAL C 14 ? N VAL C 12 O ILE C 114 ? O ILE C 112 I 2 3 O LEU C 111 ? O LEU C 109 N ALA C 87 ? N ALA C 85 I 3 4 O ILE C 90 ? O ILE C 88 N PHE C 37 ? N PHE C 35 I 4 5 N TRP C 36 ? N TRP C 34 O LEU C 48 ? O LEU C 46 J 1 2 N VAL C 14 ? N VAL C 12 O ILE C 114 ? O ILE C 112 J 2 3 O LEU C 111 ? O LEU C 109 N ALA C 87 ? N ALA C 85 J 3 4 N VAL C 93 ? N VAL C 91 O HIS C 104 ? O HIS C 102 K 1 2 N TYR C 158 ? N TYR C 156 O TRP C 180 ? O TRP C 178 K 2 3 O ALA C 179 ? O ALA C 177 N CYS C 138 ? N CYS C 136 K 3 4 O LEU C 139 ? O LEU C 137 N TYR C 125 ? N TYR C 123 K 4 5 N ARG C 128 ? N ARG C 126 O GLU D 127 ? O GLU D 126 K 5 6 N PHE D 126 ? N PHE D 125 O VAL D 142 ? O VAL D 141 K 6 7 N PHE D 148 ? N PHE D 147 O TYR D 186 ? O TYR D 185 K 7 8 O ARG D 191 ? O ARG D 190 N CYS D 169 ? N CYS D 168 L 1 2 N MET C 167 ? N MET C 165 O PHE C 172 ? O PHE C 170 L 2 3 O ALA C 179 ? O ALA C 177 N CYS C 138 ? N CYS C 136 L 3 4 O LEU C 139 ? O LEU C 137 N TYR C 125 ? N TYR C 123 L 4 5 N ARG C 128 ? N ARG C 126 O GLU D 127 ? O GLU D 126 L 5 6 N PHE D 126 ? N PHE D 125 O VAL D 142 ? O VAL D 141 L 6 7 N PHE D 148 ? N PHE D 147 O TYR D 186 ? O TYR D 185 L 7 8 O SER D 187 ? O SER D 186 N LEU D 175 ? N LEU D 174 M 1 2 N THR D 6 ? N THR D 5 O ASN D 25 ? O ASN D 24 M 2 3 N LEU D 22 ? N LEU D 21 O LEU D 77 ? O LEU D 76 M 3 4 O ILE D 78 ? O ILE D 77 N LYS D 66 ? N LYS D 65 N 1 2 N ALA D 14 ? N ALA D 13 O LEU D 112 ? O LEU D 111 N 2 3 O LEU D 109 ? O LEU D 108 N SER D 88 ? N SER D 87 N 3 4 O PHE D 91 ? O PHE D 90 N TYR D 36 ? N TYR D 35 N 4 5 N TRP D 35 ? N TRP D 34 O ILE D 47 ? O ILE D 46 N 5 6 N TYR D 49 ? N TYR D 48 O GLU D 57 ? O GLU D 56 O 1 2 N ALA D 14 ? N ALA D 13 O LEU D 112 ? O LEU D 111 O 2 3 O LEU D 109 ? O LEU D 108 N SER D 88 ? N SER D 87 O 3 4 N SER D 94 ? N SER D 93 O TYR D 102 ? O TYR D 101 P 1 2 O LYS D 162 ? O LYS D 161 N VAL D 159 ? N VAL D 158 P 2 3 N GLU D 154 ? N GLU D 153 O GLN D 211 ? O GLN D 210 P 3 4 N PHE D 206 ? N PHE D 205 O ALA D 237 ? O ALA D 236 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 301' AC2 Software ? ? ? ? 15 'BINDING SITE FOR RESIDUE 1LA A 307' AC3 Software ? ? ? ? 7 'BINDING SITE FOR LINKED RESIDUES A 302 to 303' AC4 Software ? ? ? ? 8 'BINDING SITE FOR LINKED RESIDUES A 304 to 306' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 3 ALA A 19 ? ALA A 19 . ? 1_555 ? 2 AC1 3 ASN A 20 ? ASN A 20 . ? 1_555 ? 3 AC1 3 SER A 22 ? SER A 22 . ? 1_555 ? 4 AC2 15 CYS A 12 ? CYS A 12 . ? 1_555 ? 5 AC2 15 GLN A 14 ? GLN A 14 . ? 1_555 ? 6 AC2 15 TYR A 73 ? TYR A 73 . ? 1_555 ? 7 AC2 15 SER A 76 ? SER A 76 . ? 1_555 ? 8 AC2 15 ASP A 80 ? ASP A 80 . ? 1_555 ? 9 AC2 15 TRP A 133 ? TRP A 133 . ? 1_555 ? 10 AC2 15 ASP A 153 ? ASP A 153 . ? 1_555 ? 11 AC2 15 GLY A 155 ? GLY A 155 . ? 1_555 ? 12 AC2 15 THR A 156 ? THR A 156 . ? 1_555 ? 13 AC2 15 HOH L . ? HOH A 419 . ? 1_555 ? 14 AC2 15 PRO C 30 ? PRO C 28 . ? 1_555 ? 15 AC2 15 ASN C 32 ? ASN C 30 . ? 1_555 ? 16 AC2 15 GLN C 54 ? GLN C 52 . ? 1_555 ? 17 AC2 15 ARG C 96 ? ARG C 94 . ? 1_555 ? 18 AC2 15 GLY C 97 ? GLY C 95 . ? 1_555 ? 19 AC3 7 TRP A 23 ? TRP A 23 . ? 1_555 ? 20 AC3 7 SER A 24 ? SER A 24 . ? 1_555 ? 21 AC3 7 ASN A 42 ? ASN A 42 . ? 1_555 ? 22 AC3 7 HOH L . ? HOH A 410 . ? 1_555 ? 23 AC3 7 HOH L . ? HOH A 411 . ? 1_555 ? 24 AC3 7 HOH L . ? HOH A 428 . ? 1_555 ? 25 AC3 7 HOH L . ? HOH A 439 . ? 1_555 ? 26 AC4 8 SER A 114 ? SER A 114 . ? 1_555 ? 27 AC4 8 PHE A 128 ? PHE A 128 . ? 1_555 ? 28 AC4 8 TRP A 129 ? TRP A 129 . ? 1_555 ? 29 AC4 8 GLY A 130 ? GLY A 130 . ? 1_555 ? 30 AC4 8 GLN A 161 ? GLN A 161 . ? 1_555 ? 31 AC4 8 LEU A 164 ? LEU A 164 . ? 1_555 ? 32 AC4 8 ASN A 165 ? ASN A 165 . ? 1_555 ? 33 AC4 8 HOH L . ? HOH A 424 . ? 1_555 ? # _database_PDB_matrix.entry_id 4IRS _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 4IRS _atom_sites.fract_transf_matrix[1][1] 0.012663 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.005225 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.006613 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . LYS A 1 6 ? 40.737 -4.382 -17.445 1.00 68.77 ? 6 LYS A N 1 ATOM 2 C CA . LYS A 1 6 ? 41.308 -3.001 -17.406 1.00 71.39 ? 6 LYS A CA 1 ATOM 3 C C . LYS A 1 6 ? 40.207 -1.927 -17.355 1.00 71.56 ? 6 LYS A C 1 ATOM 4 O O . LYS A 1 6 ? 39.393 -1.792 -18.288 1.00 68.31 ? 6 LYS A O 1 ATOM 5 C CB . LYS A 1 6 ? 42.261 -2.777 -18.592 1.00 73.89 ? 6 LYS A CB 1 ATOM 6 C CG . LYS A 1 6 ? 43.122 -1.503 -18.507 1.00 74.35 ? 6 LYS A CG 1 ATOM 7 C CD . LYS A 1 6 ? 44.552 -1.738 -19.009 1.00 76.47 ? 6 LYS A CD 1 ATOM 8 C CE . LYS A 1 6 ? 44.626 -2.015 -20.520 1.00 76.58 ? 6 LYS A CE 1 ATOM 9 N NZ . LYS A 1 6 ? 46.034 -2.219 -21.008 1.00 73.29 ? 6 LYS A NZ 1 ATOM 10 N N . ASN A 1 7 ? 40.192 -1.176 -16.252 1.00 66.63 ? 7 ASN A N 1 ATOM 11 C CA . ASN A 1 7 ? 39.213 -0.104 -16.045 1.00 63.56 ? 7 ASN A CA 1 ATOM 12 C C . ASN A 1 7 ? 39.683 1.219 -16.664 1.00 57.98 ? 7 ASN A C 1 ATOM 13 O O . ASN A 1 7 ? 40.691 1.795 -16.234 1.00 58.36 ? 7 ASN A O 1 ATOM 14 C CB . ASN A 1 7 ? 38.904 0.067 -14.546 1.00 63.51 ? 7 ASN A CB 1 ATOM 15 C CG . ASN A 1 7 ? 38.141 -1.120 -13.956 1.00 62.11 ? 7 ASN A CG 1 ATOM 16 O OD1 . ASN A 1 7 ? 37.346 -1.773 -14.639 1.00 58.02 ? 7 ASN A OD1 1 ATOM 17 N ND2 . ASN A 1 7 ? 38.376 -1.392 -12.674 1.00 61.89 ? 7 ASN A ND2 1 ATOM 18 N N . TYR A 1 8 ? 38.962 1.697 -17.676 1.00 49.38 ? 8 TYR A N 1 ATOM 19 C CA . TYR A 1 8 ? 39.392 2.898 -18.393 1.00 44.25 ? 8 TYR A CA 1 ATOM 20 C C . TYR A 1 8 ? 38.732 4.172 -17.868 1.00 41.41 ? 8 TYR A C 1 ATOM 21 O O . TYR A 1 8 ? 37.497 4.249 -17.785 1.00 40.95 ? 8 TYR A O 1 ATOM 22 C CB . TYR A 1 8 ? 39.140 2.759 -19.891 1.00 44.06 ? 8 TYR A CB 1 ATOM 23 C CG . TYR A 1 8 ? 40.175 1.956 -20.648 1.00 42.84 ? 8 TYR A CG 1 ATOM 24 C CD1 . TYR A 1 8 ? 39.902 0.658 -21.075 1.00 42.43 ? 8 TYR A CD1 1 ATOM 25 C CD2 . TYR A 1 8 ? 41.418 2.507 -20.961 1.00 44.14 ? 8 TYR A CD2 1 ATOM 26 C CE1 . TYR A 1 8 ? 40.846 -0.081 -21.793 1.00 45.91 ? 8 TYR A CE1 1 ATOM 27 C CE2 . TYR A 1 8 ? 42.380 1.780 -21.669 1.00 45.68 ? 8 TYR A CE2 1 ATOM 28 C CZ . TYR A 1 8 ? 42.088 0.487 -22.086 1.00 48.04 ? 8 TYR A CZ 1 ATOM 29 O OH . TYR A 1 8 ? 43.034 -0.233 -22.790 1.00 48.34 ? 8 TYR A OH 1 ATOM 30 N N . THR A 1 9 ? 39.567 5.156 -17.512 1.00 35.81 ? 9 THR A N 1 ATOM 31 C CA . THR A 1 9 ? 39.096 6.470 -17.079 1.00 32.11 ? 9 THR A CA 1 ATOM 32 C C . THR A 1 9 ? 39.175 7.513 -18.192 1.00 29.84 ? 9 THR A C 1 ATOM 33 O O . THR A 1 9 ? 40.241 7.793 -18.744 1.00 28.60 ? 9 THR A O 1 ATOM 34 C CB . THR A 1 9 ? 39.855 7.006 -15.839 1.00 32.29 ? 9 THR A CB 1 ATOM 35 O OG1 . THR A 1 9 ? 39.627 6.141 -14.724 1.00 32.79 ? 9 THR A OG1 1 ATOM 36 C CG2 . THR A 1 9 ? 39.355 8.395 -15.469 1.00 31.89 ? 9 THR A CG2 1 ATOM 37 N N . PHE A 1 10 ? 38.022 8.095 -18.488 1.00 27.66 ? 10 PHE A N 1 ATOM 38 C CA . PHE A 1 10 ? 37.899 9.183 -19.434 1.00 25.87 ? 10 PHE A CA 1 ATOM 39 C C . PHE A 1 10 ? 37.905 10.506 -18.677 1.00 25.61 ? 10 PHE A C 1 ATOM 40 O O . PHE A 1 10 ? 37.139 10.695 -17.729 1.00 25.57 ? 10 PHE A O 1 ATOM 41 C CB . PHE A 1 10 ? 36.598 8.995 -20.192 1.00 25.43 ? 10 PHE A CB 1 ATOM 42 C CG . PHE A 1 10 ? 36.325 10.034 -21.212 1.00 24.78 ? 10 PHE A CG 1 ATOM 43 C CD1 . PHE A 1 10 ? 37.099 10.115 -22.358 1.00 24.67 ? 10 PHE A CD1 1 ATOM 44 C CD2 . PHE A 1 10 ? 35.255 10.906 -21.045 1.00 24.80 ? 10 PHE A CD2 1 ATOM 45 C CE1 . PHE A 1 10 ? 36.834 11.059 -23.317 1.00 24.50 ? 10 PHE A CE1 1 ATOM 46 C CE2 . PHE A 1 10 ? 34.972 11.856 -21.988 1.00 24.83 ? 10 PHE A CE2 1 ATOM 47 C CZ . PHE A 1 10 ? 35.768 11.934 -23.141 1.00 25.68 ? 10 PHE A CZ 1 ATOM 48 N N . ARG A 1 11 ? 38.784 11.414 -19.094 1.00 25.54 ? 11 ARG A N 1 ATOM 49 C CA . ARG A 1 11 ? 38.996 12.669 -18.399 1.00 24.93 ? 11 ARG A CA 1 ATOM 50 C C . ARG A 1 11 ? 38.901 13.884 -19.310 1.00 24.66 ? 11 ARG A C 1 ATOM 51 O O . ARG A 1 11 ? 39.597 13.964 -20.313 1.00 24.09 ? 11 ARG A O 1 ATOM 52 C CB . ARG A 1 11 ? 40.377 12.657 -17.776 1.00 25.99 ? 11 ARG A CB 1 ATOM 53 C CG . ARG A 1 11 ? 40.434 12.011 -16.443 1.00 28.19 ? 11 ARG A CG 1 ATOM 54 C CD . ARG A 1 11 ? 41.846 12.019 -15.901 1.00 30.11 ? 11 ARG A CD 1 ATOM 55 N NE . ARG A 1 11 ? 41.835 11.534 -14.528 1.00 32.56 ? 11 ARG A NE 1 ATOM 56 C CZ . ARG A 1 11 ? 42.046 10.271 -14.167 1.00 33.69 ? 11 ARG A CZ 1 ATOM 57 N NH1 . ARG A 1 11 ? 42.312 9.338 -15.085 1.00 33.08 ? 11 ARG A NH1 1 ATOM 58 N NH2 . ARG A 1 11 ? 41.986 9.942 -12.878 1.00 33.41 ? 11 ARG A NH2 1 ATOM 59 N N . CYS A 1 12 ? 38.051 14.837 -18.951 1.00 24.86 ? 12 CYS A N 1 ATOM 60 C CA . CYS A 1 12 ? 38.063 16.141 -19.607 1.00 25.60 ? 12 CYS A CA 1 ATOM 61 C C . CYS A 1 12 ? 38.719 17.134 -18.682 1.00 24.89 ? 12 CYS A C 1 ATOM 62 O O . CYS A 1 12 ? 38.179 17.462 -17.640 1.00 25.74 ? 12 CYS A O 1 ATOM 63 C CB . CYS A 1 12 ? 36.648 16.602 -19.943 1.00 26.07 ? 12 CYS A CB 1 ATOM 64 S SG . CYS A 1 12 ? 35.739 15.375 -20.869 1.00 28.12 ? 12 CYS A SG 1 ATOM 65 N N . LEU A 1 13 ? 39.898 17.605 -19.045 1.00 24.34 ? 13 LEU A N 1 ATOM 66 C CA . LEU A 1 13 ? 40.595 18.515 -18.162 1.00 23.72 ? 13 LEU A CA 1 ATOM 67 C C . LEU A 1 13 ? 40.524 19.905 -18.731 1.00 24.17 ? 13 LEU A C 1 ATOM 68 O O . LEU A 1 13 ? 41.004 20.144 -19.845 1.00 26.06 ? 13 LEU A O 1 ATOM 69 C CB . LEU A 1 13 ? 42.040 18.071 -17.948 1.00 22.65 ? 13 LEU A CB 1 ATOM 70 C CG . LEU A 1 13 ? 42.192 16.641 -17.440 1.00 21.94 ? 13 LEU A CG 1 ATOM 71 C CD1 . LEU A 1 13 ? 43.645 16.299 -17.204 1.00 22.06 ? 13 LEU A CD1 1 ATOM 72 C CD2 . LEU A 1 13 ? 41.392 16.454 -16.189 1.00 21.89 ? 13 LEU A CD2 1 ATOM 73 N N . GLN A 1 14 ? 39.896 20.802 -17.970 1.00 23.29 ? 14 GLN A N 1 ATOM 74 C CA . GLN A 1 14 ? 39.775 22.207 -18.329 1.00 22.52 ? 14 GLN A CA 1 ATOM 75 C C . GLN A 1 14 ? 40.575 23.079 -17.376 1.00 23.10 ? 14 GLN A C 1 ATOM 76 O O . GLN A 1 14 ? 40.502 22.917 -16.150 1.00 23.41 ? 14 GLN A O 1 ATOM 77 C CB . GLN A 1 14 ? 38.325 22.645 -18.291 1.00 21.98 ? 14 GLN A CB 1 ATOM 78 C CG . GLN A 1 14 ? 38.132 24.092 -18.671 1.00 22.69 ? 14 GLN A CG 1 ATOM 79 C CD . GLN A 1 14 ? 36.708 24.537 -18.479 1.00 23.92 ? 14 GLN A CD 1 ATOM 80 O OE1 . GLN A 1 14 ? 35.783 23.908 -18.992 1.00 24.11 ? 14 GLN A OE1 1 ATOM 81 N NE2 . GLN A 1 14 ? 36.515 25.631 -17.736 1.00 23.88 ? 14 GLN A NE2 1 ATOM 82 N N . MET A 1 15 ? 41.335 24.007 -17.944 1.00 22.79 ? 15 MET A N 1 ATOM 83 C CA . MET A 1 15 ? 42.078 24.954 -17.155 1.00 23.22 ? 15 MET A CA 1 ATOM 84 C C . MET A 1 15 ? 41.787 26.357 -17.670 1.00 23.49 ? 15 MET A C 1 ATOM 85 O O . MET A 1 15 ? 41.910 26.630 -18.876 1.00 22.42 ? 15 MET A O 1 ATOM 86 C CB . MET A 1 15 ? 43.571 24.615 -17.156 1.00 23.96 ? 15 MET A CB 1 ATOM 87 C CG . MET A 1 15 ? 44.205 24.518 -18.530 1.00 25.93 ? 15 MET A CG 1 ATOM 88 S SD . MET A 1 15 ? 45.453 23.214 -18.628 1.00 29.90 ? 15 MET A SD 1 ATOM 89 C CE . MET A 1 15 ? 44.502 21.781 -19.183 1.00 26.30 ? 15 MET A CE 1 ATOM 90 N N . SER A 1 16 ? 41.381 27.231 -16.747 1.00 23.63 ? 16 SER A N 1 ATOM 91 C CA . SER A 1 16 ? 40.993 28.594 -17.076 1.00 24.14 ? 16 SER A CA 1 ATOM 92 C C . SER A 1 16 ? 41.702 29.611 -16.189 1.00 24.59 ? 16 SER A C 1 ATOM 93 O O . SER A 1 16 ? 41.717 29.488 -14.966 1.00 24.53 ? 16 SER A O 1 ATOM 94 C CB . SER A 1 16 ? 39.479 28.755 -16.960 1.00 25.12 ? 16 SER A CB 1 ATOM 95 O OG . SER A 1 16 ? 38.791 27.738 -17.676 1.00 26.05 ? 16 SER A OG 1 ATOM 96 N N . SER A 1 17 ? 42.294 30.619 -16.818 1.00 26.25 ? 17 SER A N 1 ATOM 97 C CA . SER A 1 17 ? 43.008 31.665 -16.098 1.00 27.39 ? 17 SER A CA 1 ATOM 98 C C . SER A 1 17 ? 42.318 32.990 -16.297 1.00 27.98 ? 17 SER A C 1 ATOM 99 O O . SER A 1 17 ? 41.941 33.328 -17.418 1.00 30.07 ? 17 SER A O 1 ATOM 100 C CB . SER A 1 17 ? 44.440 31.788 -16.608 1.00 27.60 ? 17 SER A CB 1 ATOM 101 O OG . SER A 1 17 ? 45.061 30.521 -16.662 1.00 28.31 ? 17 SER A OG 1 ATOM 102 N N . PHE A 1 18 ? 42.156 33.733 -15.210 1.00 27.50 ? 18 PHE A N 1 ATOM 103 C CA . PHE A 1 18 ? 41.646 35.090 -15.280 1.00 29.29 ? 18 PHE A CA 1 ATOM 104 C C . PHE A 1 18 ? 42.657 36.015 -14.623 1.00 31.57 ? 18 PHE A C 1 ATOM 105 O O . PHE A 1 18 ? 42.836 35.967 -13.402 1.00 32.32 ? 18 PHE A O 1 ATOM 106 C CB . PHE A 1 18 ? 40.294 35.182 -14.579 1.00 28.85 ? 18 PHE A CB 1 ATOM 107 C CG . PHE A 1 18 ? 39.303 34.167 -15.053 1.00 28.68 ? 18 PHE A CG 1 ATOM 108 C CD1 . PHE A 1 18 ? 39.352 32.862 -14.584 1.00 28.16 ? 18 PHE A CD1 1 ATOM 109 C CD2 . PHE A 1 18 ? 38.328 34.517 -15.979 1.00 29.01 ? 18 PHE A CD2 1 ATOM 110 C CE1 . PHE A 1 18 ? 38.452 31.922 -15.031 1.00 29.37 ? 18 PHE A CE1 1 ATOM 111 C CE2 . PHE A 1 18 ? 37.416 33.589 -16.435 1.00 29.34 ? 18 PHE A CE2 1 ATOM 112 C CZ . PHE A 1 18 ? 37.473 32.282 -15.962 1.00 29.89 ? 18 PHE A CZ 1 ATOM 113 N N . ALA A 1 19 ? 43.328 36.840 -15.431 1.00 33.33 ? 19 ALA A N 1 ATOM 114 C CA . ALA A 1 19 ? 44.432 37.680 -14.942 1.00 34.84 ? 19 ALA A CA 1 ATOM 115 C C . ALA A 1 19 ? 43.941 38.936 -14.233 1.00 36.36 ? 19 ALA A C 1 ATOM 116 O O . ALA A 1 19 ? 44.518 39.358 -13.229 1.00 36.37 ? 19 ALA A O 1 ATOM 117 C CB . ALA A 1 19 ? 45.367 38.050 -16.079 1.00 34.78 ? 19 ALA A CB 1 ATOM 118 N N . ASN A 1 20 ? 42.880 39.522 -14.782 1.00 38.05 ? 20 ASN A N 1 ATOM 119 C CA . ASN A 1 20 ? 42.263 40.741 -14.273 1.00 39.83 ? 20 ASN A CA 1 ATOM 120 C C . ASN A 1 20 ? 40.783 40.741 -14.705 1.00 40.70 ? 20 ASN A C 1 ATOM 121 O O . ASN A 1 20 ? 40.258 39.689 -15.049 1.00 41.26 ? 20 ASN A O 1 ATOM 122 C CB . ASN A 1 20 ? 43.035 41.976 -14.763 1.00 40.38 ? 20 ASN A CB 1 ATOM 123 C CG . ASN A 1 20 ? 43.514 41.833 -16.188 1.00 42.89 ? 20 ASN A CG 1 ATOM 124 O OD1 . ASN A 1 20 ? 42.706 41.705 -17.105 1.00 42.10 ? 20 ASN A OD1 1 ATOM 125 N ND2 . ASN A 1 20 ? 44.841 41.849 -16.380 1.00 48.27 ? 20 ASN A ND2 1 ATOM 126 N N . ARG A 1 21 ? 40.112 41.895 -14.682 1.00 41.98 ? 21 ARG A N 1 ATOM 127 C CA . ARG A 1 21 ? 38.676 41.981 -15.014 1.00 39.61 ? 21 ARG A CA 1 ATOM 128 C C . ARG A 1 21 ? 38.372 41.657 -16.483 1.00 39.40 ? 21 ARG A C 1 ATOM 129 O O . ARG A 1 21 ? 37.260 41.243 -16.806 1.00 37.18 ? 21 ARG A O 1 ATOM 130 C CB . ARG A 1 21 ? 38.084 43.351 -14.620 1.00 36.73 ? 21 ARG A CB 1 ATOM 131 N N . SER A 1 22 ? 39.359 41.811 -17.364 1.00 39.23 ? 22 SER A N 1 ATOM 132 C CA . SER A 1 22 ? 39.096 41.681 -18.794 1.00 42.42 ? 22 SER A CA 1 ATOM 133 C C . SER A 1 22 ? 39.756 40.486 -19.491 1.00 44.74 ? 22 SER A C 1 ATOM 134 O O . SER A 1 22 ? 39.184 39.934 -20.433 1.00 51.82 ? 22 SER A O 1 ATOM 135 C CB . SER A 1 22 ? 39.450 42.979 -19.532 1.00 44.71 ? 22 SER A CB 1 ATOM 136 O OG . SER A 1 22 ? 40.732 43.451 -19.144 1.00 47.02 ? 22 SER A OG 1 ATOM 137 N N . TRP A 1 23 ? 40.942 40.091 -19.041 1.00 39.59 ? 23 TRP A N 1 ATOM 138 C CA . TRP A 1 23 ? 41.741 39.078 -19.732 1.00 35.79 ? 23 TRP A CA 1 ATOM 139 C C . TRP A 1 23 ? 41.482 37.684 -19.228 1.00 35.32 ? 23 TRP A C 1 ATOM 140 O O . TRP A 1 23 ? 41.408 37.453 -18.021 1.00 38.40 ? 23 TRP A O 1 ATOM 141 C CB . TRP A 1 23 ? 43.199 39.423 -19.549 1.00 34.34 ? 23 TRP A CB 1 ATOM 142 C CG . TRP A 1 23 ? 44.168 38.594 -20.336 1.00 33.03 ? 23 TRP A CG 1 ATOM 143 C CD1 . TRP A 1 23 ? 44.771 38.920 -21.544 1.00 31.80 ? 23 TRP A CD1 1 ATOM 144 C CD2 . TRP A 1 23 ? 44.723 37.284 -19.972 1.00 33.59 ? 23 TRP A CD2 1 ATOM 145 N NE1 . TRP A 1 23 ? 45.633 37.934 -21.943 1.00 32.25 ? 23 TRP A NE1 1 ATOM 146 C CE2 . TRP A 1 23 ? 45.653 36.922 -21.054 1.00 32.69 ? 23 TRP A CE2 1 ATOM 147 C CE3 . TRP A 1 23 ? 44.545 36.398 -18.902 1.00 34.07 ? 23 TRP A CE3 1 ATOM 148 C CZ2 . TRP A 1 23 ? 46.366 35.728 -21.045 1.00 31.92 ? 23 TRP A CZ2 1 ATOM 149 C CZ3 . TRP A 1 23 ? 45.272 35.196 -18.905 1.00 33.21 ? 23 TRP A CZ3 1 ATOM 150 C CH2 . TRP A 1 23 ? 46.160 34.872 -19.955 1.00 32.60 ? 23 TRP A CH2 1 ATOM 151 N N . SER A 1 24 ? 41.384 36.726 -20.144 1.00 32.96 ? 24 SER A N 1 ATOM 152 C CA . SER A 1 24 ? 41.003 35.363 -19.787 1.00 30.01 ? 24 SER A CA 1 ATOM 153 C C . SER A 1 24 ? 41.318 34.373 -20.907 1.00 28.35 ? 24 SER A C 1 ATOM 154 O O . SER A 1 24 ? 41.136 34.681 -22.081 1.00 28.69 ? 24 SER A O 1 ATOM 155 C CB . SER A 1 24 ? 39.507 35.336 -19.455 1.00 30.25 ? 24 SER A CB 1 ATOM 156 O OG . SER A 1 24 ? 38.966 34.037 -19.550 1.00 31.66 ? 24 SER A OG 1 ATOM 157 N N . ARG A 1 25 ? 41.792 33.185 -20.551 1.00 26.51 ? 25 ARG A N 1 ATOM 158 C CA . ARG A 1 25 ? 41.929 32.103 -21.530 1.00 25.68 ? 25 ARG A CA 1 ATOM 159 C C . ARG A 1 25 ? 41.482 30.775 -20.927 1.00 24.86 ? 25 ARG A C 1 ATOM 160 O O . ARG A 1 25 ? 41.659 30.538 -19.721 1.00 22.89 ? 25 ARG A O 1 ATOM 161 C CB . ARG A 1 25 ? 43.356 32.008 -22.123 1.00 26.29 ? 25 ARG A CB 1 ATOM 162 C CG . ARG A 1 25 ? 44.445 31.517 -21.152 1.00 27.53 ? 25 ARG A CG 1 ATOM 163 C CD . ARG A 1 25 ? 45.725 31.008 -21.834 1.00 28.62 ? 25 ARG A CD 1 ATOM 164 N NE . ARG A 1 25 ? 45.476 30.350 -23.121 1.00 29.75 ? 25 ARG A NE 1 ATOM 165 C CZ . ARG A 1 25 ? 46.030 30.728 -24.271 1.00 29.69 ? 25 ARG A CZ 1 ATOM 166 N NH1 . ARG A 1 25 ? 46.885 31.744 -24.290 1.00 28.91 ? 25 ARG A NH1 1 ATOM 167 N NH2 . ARG A 1 25 ? 45.739 30.090 -25.400 1.00 29.37 ? 25 ARG A NH2 1 ATOM 168 N N . THR A 1 26 ? 40.887 29.932 -21.778 1.00 24.93 ? 26 THR A N 1 ATOM 169 C CA . THR A 1 26 ? 40.446 28.583 -21.402 1.00 24.54 ? 26 THR A CA 1 ATOM 170 C C . THR A 1 26 ? 40.944 27.545 -22.410 1.00 24.71 ? 26 THR A C 1 ATOM 171 O O . THR A 1 26 ? 40.646 27.624 -23.598 1.00 26.14 ? 26 THR A O 1 ATOM 172 C CB . THR A 1 26 ? 38.909 28.502 -21.254 1.00 23.72 ? 26 THR A CB 1 ATOM 173 O OG1 . THR A 1 26 ? 38.504 29.277 -20.129 1.00 23.83 ? 26 THR A OG1 1 ATOM 174 C CG2 . THR A 1 26 ? 38.450 27.083 -21.026 1.00 23.76 ? 26 THR A CG2 1 ATOM 175 N N . ASP A 1 27 ? 41.701 26.574 -21.913 1.00 24.82 ? 27 ASP A N 1 ATOM 176 C CA . ASP A 1 27 ? 42.250 25.502 -22.730 1.00 25.11 ? 27 ASP A CA 1 ATOM 177 C C . ASP A 1 27 ? 41.796 24.157 -22.165 1.00 25.05 ? 27 ASP A C 1 ATOM 178 O O . ASP A 1 27 ? 41.667 24.011 -20.948 1.00 25.54 ? 27 ASP A O 1 ATOM 179 C CB . ASP A 1 27 ? 43.779 25.600 -22.748 1.00 25.57 ? 27 ASP A CB 1 ATOM 180 C CG . ASP A 1 27 ? 44.267 26.941 -23.277 1.00 27.57 ? 27 ASP A CG 1 ATOM 181 O OD1 . ASP A 1 27 ? 44.234 27.145 -24.505 1.00 29.14 ? 27 ASP A OD1 1 ATOM 182 O OD2 . ASP A 1 27 ? 44.673 27.811 -22.473 1.00 28.22 ? 27 ASP A OD2 1 ATOM 183 N N . SER A 1 28 ? 41.546 23.179 -23.035 1.00 24.73 ? 28 SER A N 1 ATOM 184 C CA . SER A 1 28 ? 41.174 21.832 -22.571 1.00 24.54 ? 28 SER A CA 1 ATOM 185 C C . SER A 1 28 ? 41.899 20.725 -23.299 1.00 23.44 ? 28 SER A C 1 ATOM 186 O O . SER A 1 28 ? 42.190 20.837 -24.486 1.00 23.77 ? 28 SER A O 1 ATOM 187 C CB . SER A 1 28 ? 39.667 21.600 -22.666 1.00 24.50 ? 28 SER A CB 1 ATOM 188 O OG . SER A 1 28 ? 38.955 22.746 -22.240 1.00 25.86 ? 28 SER A OG 1 ATOM 189 N N . VAL A 1 29 ? 42.204 19.661 -22.568 1.00 22.81 ? 29 VAL A N 1 ATOM 190 C CA . VAL A 1 29 ? 42.715 18.429 -23.170 1.00 22.49 ? 29 VAL A CA 1 ATOM 191 C C . VAL A 1 29 ? 41.802 17.309 -22.673 1.00 22.64 ? 29 VAL A C 1 ATOM 192 O O . VAL A 1 29 ? 41.133 17.455 -21.632 1.00 22.82 ? 29 VAL A O 1 ATOM 193 C CB . VAL A 1 29 ? 44.200 18.158 -22.834 1.00 20.45 ? 29 VAL A CB 1 ATOM 194 N N . VAL A 1 30 ? 41.739 16.220 -23.433 1.00 21.70 ? 30 VAL A N 1 ATOM 195 C CA . VAL A 1 30 ? 40.881 15.100 -23.097 1.00 21.36 ? 30 VAL A CA 1 ATOM 196 C C . VAL A 1 30 ? 41.704 13.818 -23.171 1.00 21.87 ? 30 VAL A C 1 ATOM 197 O O . VAL A 1 30 ? 42.498 13.650 -24.097 1.00 22.79 ? 30 VAL A O 1 ATOM 198 C CB . VAL A 1 30 ? 39.671 15.066 -24.031 1.00 21.23 ? 30 VAL A CB 1 ATOM 199 C CG1 . VAL A 1 30 ? 38.764 13.886 -23.741 1.00 20.55 ? 30 VAL A CG1 1 ATOM 200 C CG2 . VAL A 1 30 ? 38.896 16.366 -23.894 1.00 21.71 ? 30 VAL A CG2 1 ATOM 201 N N . TRP A 1 31 ? 41.527 12.938 -22.182 1.00 22.02 ? 31 TRP A N 1 ATOM 202 C CA . TRP A 1 31 ? 42.285 11.692 -22.066 1.00 22.64 ? 31 TRP A CA 1 ATOM 203 C C . TRP A 1 31 ? 41.404 10.489 -21.921 1.00 23.35 ? 31 TRP A C 1 ATOM 204 O O . TRP A 1 31 ? 40.403 10.530 -21.197 1.00 23.77 ? 31 TRP A O 1 ATOM 205 C CB . TRP A 1 31 ? 43.172 11.737 -20.834 1.00 23.39 ? 31 TRP A CB 1 ATOM 206 C CG . TRP A 1 31 ? 44.173 12.855 -20.826 1.00 23.16 ? 31 TRP A CG 1 ATOM 207 C CD1 . TRP A 1 31 ? 44.039 14.104 -20.240 1.00 22.86 ? 31 TRP A CD1 1 ATOM 208 C CD2 . TRP A 1 31 ? 45.507 12.852 -21.426 1.00 23.50 ? 31 TRP A CD2 1 ATOM 209 N NE1 . TRP A 1 31 ? 45.163 14.855 -20.436 1.00 23.34 ? 31 TRP A NE1 1 ATOM 210 C CE2 . TRP A 1 31 ? 46.084 14.166 -21.144 1.00 23.67 ? 31 TRP A CE2 1 ATOM 211 C CE3 . TRP A 1 31 ? 46.255 11.928 -22.153 1.00 23.82 ? 31 TRP A CE3 1 ATOM 212 C CZ2 . TRP A 1 31 ? 47.356 14.526 -21.588 1.00 23.96 ? 31 TRP A CZ2 1 ATOM 213 C CZ3 . TRP A 1 31 ? 47.539 12.298 -22.589 1.00 23.29 ? 31 TRP A CZ3 1 ATOM 214 C CH2 . TRP A 1 31 ? 48.071 13.566 -22.315 1.00 23.29 ? 31 TRP A CH2 1 ATOM 215 N N . LEU A 1 32 ? 41.774 9.398 -22.591 1.00 23.73 ? 32 LEU A N 1 ATOM 216 C CA . LEU A 1 32 ? 41.188 8.081 -22.333 1.00 24.02 ? 32 LEU A CA 1 ATOM 217 C C . LEU A 1 32 ? 42.301 7.180 -21.831 1.00 24.78 ? 32 LEU A C 1 ATOM 218 O O . LEU A 1 32 ? 43.161 6.755 -22.607 1.00 26.71 ? 32 LEU A O 1 ATOM 219 C CB . LEU A 1 32 ? 40.548 7.497 -23.595 1.00 23.96 ? 32 LEU A CB 1 ATOM 220 C CG . LEU A 1 32 ? 39.679 6.234 -23.437 1.00 24.24 ? 32 LEU A CG 1 ATOM 221 C CD1 . LEU A 1 32 ? 38.802 6.237 -22.178 1.00 23.83 ? 32 LEU A CD1 1 ATOM 222 C CD2 . LEU A 1 32 ? 38.799 6.052 -24.658 1.00 24.81 ? 32 LEU A CD2 1 ATOM 223 N N . GLY A 1 33 ? 42.294 6.891 -20.533 1.00 24.67 ? 33 GLY A N 1 ATOM 224 C CA . GLY A 1 33 ? 43.465 6.313 -19.890 1.00 24.80 ? 33 GLY A CA 1 ATOM 225 C C . GLY A 1 33 ? 44.582 7.338 -19.988 1.00 25.31 ? 33 GLY A C 1 ATOM 226 O O . GLY A 1 33 ? 44.408 8.470 -19.572 1.00 26.06 ? 33 GLY A O 1 ATOM 227 N N . ASP A 1 34 ? 45.709 6.951 -20.576 1.00 26.39 ? 34 ASP A N 1 ATOM 228 C CA . ASP A 1 34 ? 46.857 7.838 -20.745 1.00 27.43 ? 34 ASP A CA 1 ATOM 229 C C . ASP A 1 34 ? 47.052 8.320 -22.198 1.00 28.46 ? 34 ASP A C 1 ATOM 230 O O . ASP A 1 34 ? 48.132 8.824 -22.543 1.00 29.15 ? 34 ASP A O 1 ATOM 231 C CB . ASP A 1 34 ? 48.137 7.161 -20.240 1.00 27.72 ? 34 ASP A CB 1 ATOM 232 C CG . ASP A 1 34 ? 48.450 5.883 -20.983 1.00 29.49 ? 34 ASP A CG 1 ATOM 233 O OD1 . ASP A 1 34 ? 47.671 5.504 -21.884 1.00 29.49 ? 34 ASP A OD1 1 ATOM 234 O OD2 . ASP A 1 34 ? 49.485 5.250 -20.678 1.00 32.30 ? 34 ASP A OD2 1 ATOM 235 N N . LEU A 1 35 ? 46.018 8.172 -23.033 1.00 27.34 ? 35 LEU A N 1 ATOM 236 C CA . LEU A 1 35 ? 46.071 8.631 -24.426 1.00 26.26 ? 35 LEU A CA 1 ATOM 237 C C . LEU A 1 35 ? 45.227 9.872 -24.657 1.00 25.50 ? 35 LEU A C 1 ATOM 238 O O . LEU A 1 35 ? 44.041 9.868 -24.359 1.00 27.22 ? 35 LEU A O 1 ATOM 239 C CB . LEU A 1 35 ? 45.619 7.514 -25.375 1.00 26.58 ? 35 LEU A CB 1 ATOM 240 C CG . LEU A 1 35 ? 46.471 6.235 -25.394 1.00 26.43 ? 35 LEU A CG 1 ATOM 241 C CD1 . LEU A 1 35 ? 45.823 5.134 -26.229 1.00 25.20 ? 35 LEU A CD1 1 ATOM 242 C CD2 . LEU A 1 35 ? 47.865 6.548 -25.893 1.00 26.36 ? 35 LEU A CD2 1 ATOM 243 N N . GLN A 1 36 ? 45.826 10.933 -25.193 1.00 24.96 ? 36 GLN A N 1 ATOM 244 C CA . GLN A 1 36 ? 45.065 12.149 -25.510 1.00 24.00 ? 36 GLN A CA 1 ATOM 245 C C . GLN A 1 36 ? 44.152 11.919 -26.718 1.00 24.06 ? 36 GLN A C 1 ATOM 246 O O . GLN A 1 36 ? 44.592 11.397 -27.752 1.00 23.89 ? 36 GLN A O 1 ATOM 247 C CB . GLN A 1 36 ? 45.991 13.349 -25.737 1.00 23.81 ? 36 GLN A CB 1 ATOM 248 C CG . GLN A 1 36 ? 45.249 14.671 -25.971 1.00 24.10 ? 36 GLN A CG 1 ATOM 249 C CD . GLN A 1 36 ? 46.158 15.905 -26.021 1.00 23.97 ? 36 GLN A CD 1 ATOM 250 O OE1 . GLN A 1 36 ? 47.383 15.823 -25.913 1.00 23.47 ? 36 GLN A OE1 1 ATOM 251 N NE2 . GLN A 1 36 ? 45.543 17.058 -26.195 1.00 24.38 ? 36 GLN A NE2 1 ATOM 252 N N . THR A 1 37 ? 42.882 12.304 -26.578 1.00 23.73 ? 37 THR A N 1 ATOM 253 C CA . THR A 1 37 ? 41.895 12.124 -27.647 1.00 23.12 ? 37 THR A CA 1 ATOM 254 C C . THR A 1 37 ? 41.384 13.433 -28.232 1.00 22.37 ? 37 THR A C 1 ATOM 255 O O . THR A 1 37 ? 40.904 13.459 -29.359 1.00 22.44 ? 37 THR A O 1 ATOM 256 C CB . THR A 1 37 ? 40.673 11.269 -27.196 1.00 23.14 ? 37 THR A CB 1 ATOM 257 O OG1 . THR A 1 37 ? 39.923 11.961 -26.185 1.00 22.22 ? 37 THR A OG1 1 ATOM 258 C CG2 . THR A 1 37 ? 41.120 9.922 -26.672 1.00 23.39 ? 37 THR A CG2 1 ATOM 259 N N . HIS A 1 38 ? 41.441 14.505 -27.456 1.00 22.25 ? 38 HIS A N 1 ATOM 260 C CA . HIS A 1 38 ? 41.022 15.823 -27.947 1.00 23.12 ? 38 HIS A CA 1 ATOM 261 C C . HIS A 1 38 ? 41.913 16.869 -27.377 1.00 24.43 ? 38 HIS A C 1 ATOM 262 O O . HIS A 1 38 ? 42.553 16.661 -26.346 1.00 26.03 ? 38 HIS A O 1 ATOM 263 C CB . HIS A 1 38 ? 39.577 16.157 -27.581 1.00 21.90 ? 38 HIS A CB 1 ATOM 264 C CG . HIS A 1 38 ? 38.579 15.107 -27.992 1.00 21.96 ? 38 HIS A CG 1 ATOM 265 N ND1 . HIS A 1 38 ? 38.477 13.915 -27.365 1.00 22.05 ? 38 HIS A ND1 1 ATOM 266 C CD2 . HIS A 1 38 ? 37.611 15.106 -28.995 1.00 21.97 ? 38 HIS A CD2 1 ATOM 267 C CE1 . HIS A 1 38 ? 37.503 13.182 -27.947 1.00 21.94 ? 38 HIS A CE1 1 ATOM 268 N NE2 . HIS A 1 38 ? 36.968 13.915 -28.938 1.00 21.96 ? 38 HIS A NE2 1 ATOM 269 N N . ARG A 1 39 ? 41.993 17.990 -28.075 1.00 25.51 ? 39 ARG A N 1 ATOM 270 C CA . ARG A 1 39 ? 42.615 19.182 -27.561 1.00 26.00 ? 39 ARG A CA 1 ATOM 271 C C . ARG A 1 39 ? 41.625 20.262 -27.944 1.00 25.23 ? 39 ARG A C 1 ATOM 272 O O . ARG A 1 39 ? 40.990 20.184 -29.009 1.00 25.36 ? 39 ARG A O 1 ATOM 273 C CB . ARG A 1 39 ? 44.024 19.392 -28.168 1.00 28.73 ? 39 ARG A CB 1 ATOM 274 C CG . ARG A 1 39 ? 44.168 20.387 -29.350 1.00 33.73 ? 39 ARG A CG 1 ATOM 275 C CD . ARG A 1 39 ? 45.644 20.551 -29.830 1.00 36.06 ? 39 ARG A CD 1 ATOM 276 N NE . ARG A 1 39 ? 46.109 19.313 -30.461 1.00 41.93 ? 39 ARG A NE 1 ATOM 277 C CZ . ARG A 1 39 ? 47.365 18.865 -30.473 1.00 46.59 ? 39 ARG A CZ 1 ATOM 278 N NH1 . ARG A 1 39 ? 48.352 19.553 -29.894 1.00 51.48 ? 39 ARG A NH1 1 ATOM 279 N NH2 . ARG A 1 39 ? 47.643 17.715 -31.078 1.00 46.11 ? 39 ARG A NH2 1 ATOM 280 N N . TRP A 1 40 ? 41.436 21.235 -27.063 1.00 23.54 ? 40 TRP A N 1 ATOM 281 C CA . TRP A 1 40 ? 40.616 22.387 -27.401 1.00 22.72 ? 40 TRP A CA 1 ATOM 282 C C . TRP A 1 40 ? 41.210 23.616 -26.828 1.00 23.42 ? 40 TRP A C 1 ATOM 283 O O . TRP A 1 40 ? 40.984 23.939 -25.670 1.00 24.04 ? 40 TRP A O 1 ATOM 284 C CB . TRP A 1 40 ? 39.193 22.204 -26.928 1.00 21.04 ? 40 TRP A CB 1 ATOM 285 C CG . TRP A 1 40 ? 38.285 23.299 -27.388 1.00 20.55 ? 40 TRP A CG 1 ATOM 286 C CD1 . TRP A 1 40 ? 38.474 24.157 -28.457 1.00 20.80 ? 40 TRP A CD1 1 ATOM 287 C CD2 . TRP A 1 40 ? 36.982 23.673 -26.826 1.00 20.72 ? 40 TRP A CD2 1 ATOM 288 N NE1 . TRP A 1 40 ? 37.419 25.018 -28.590 1.00 21.36 ? 40 TRP A NE1 1 ATOM 289 C CE2 . TRP A 1 40 ? 36.490 24.783 -27.642 1.00 20.90 ? 40 TRP A CE2 1 ATOM 290 C CE3 . TRP A 1 40 ? 36.205 23.217 -25.770 1.00 20.18 ? 40 TRP A CE3 1 ATOM 291 C CZ2 . TRP A 1 40 ? 35.280 25.398 -27.388 1.00 20.41 ? 40 TRP A CZ2 1 ATOM 292 C CZ3 . TRP A 1 40 ? 34.982 23.845 -25.530 1.00 19.94 ? 40 TRP A CZ3 1 ATOM 293 C CH2 . TRP A 1 40 ? 34.535 24.908 -26.317 1.00 20.25 ? 40 TRP A CH2 1 ATOM 294 N N . SER A 1 41 ? 41.982 24.323 -27.640 1.00 25.64 ? 41 SER A N 1 ATOM 295 C CA . SER A 1 41 ? 42.717 25.477 -27.142 1.00 28.27 ? 41 SER A CA 1 ATOM 296 C C . SER A 1 41 ? 41.886 26.745 -27.277 1.00 29.56 ? 41 SER A C 1 ATOM 297 O O . SER A 1 41 ? 40.978 26.817 -28.117 1.00 30.58 ? 41 SER A O 1 ATOM 298 C CB . SER A 1 41 ? 44.019 25.649 -27.906 1.00 28.45 ? 41 SER A CB 1 ATOM 299 O OG . SER A 1 41 ? 43.747 26.430 -29.043 1.00 29.49 ? 41 SER A OG 1 ATOM 300 N N . ASN A 1 42 ? 42.220 27.748 -26.467 1.00 30.04 ? 42 ASN A N 1 ATOM 301 C CA . ASN A 1 42 ? 41.489 29.012 -26.460 1.00 31.23 ? 42 ASN A CA 1 ATOM 302 C C . ASN A 1 42 ? 41.356 29.615 -27.843 1.00 30.88 ? 42 ASN A C 1 ATOM 303 O O . ASN A 1 42 ? 40.310 30.155 -28.177 1.00 31.07 ? 42 ASN A O 1 ATOM 304 C CB . ASN A 1 42 ? 42.139 30.031 -25.514 1.00 31.94 ? 42 ASN A CB 1 ATOM 305 C CG . ASN A 1 42 ? 41.207 31.158 -25.163 1.00 31.40 ? 42 ASN A CG 1 ATOM 306 O OD1 . ASN A 1 42 ? 40.354 31.004 -24.306 1.00 30.36 ? 42 ASN A OD1 1 ATOM 307 N ND2 . ASN A 1 42 ? 41.369 32.295 -25.825 1.00 32.88 ? 42 ASN A ND2 1 ATOM 308 N N . ASP A 1 43 ? 42.414 29.493 -28.642 1.00 32.54 ? 43 ASP A N 1 ATOM 309 C CA . ASP A 1 43 ? 42.516 30.155 -29.954 1.00 34.54 ? 43 ASP A CA 1 ATOM 310 C C . ASP A 1 43 ? 41.533 29.612 -30.980 1.00 32.56 ? 43 ASP A C 1 ATOM 311 O O . ASP A 1 43 ? 41.207 30.302 -31.935 1.00 32.84 ? 43 ASP A O 1 ATOM 312 C CB . ASP A 1 43 ? 43.949 30.054 -30.499 1.00 38.76 ? 43 ASP A CB 1 ATOM 313 C CG . ASP A 1 43 ? 45.001 30.433 -29.448 1.00 44.90 ? 43 ASP A CG 1 ATOM 314 O OD1 . ASP A 1 43 ? 45.453 31.603 -29.445 1.00 45.82 ? 43 ASP A OD1 1 ATOM 315 O OD2 . ASP A 1 43 ? 45.346 29.572 -28.596 1.00 46.56 ? 43 ASP A OD2 1 ATOM 316 N N . SER A 1 44 ? 41.049 28.392 -30.743 1.00 29.99 ? 44 SER A N 1 ATOM 317 C CA . SER A 1 44 ? 40.284 27.605 -31.703 1.00 27.26 ? 44 SER A CA 1 ATOM 318 C C . SER A 1 44 ? 38.784 27.575 -31.403 1.00 26.89 ? 44 SER A C 1 ATOM 319 O O . SER A 1 44 ? 38.372 27.347 -30.259 1.00 26.44 ? 44 SER A O 1 ATOM 320 C CB . SER A 1 44 ? 40.849 26.185 -31.724 1.00 26.51 ? 44 SER A CB 1 ATOM 321 O OG . SER A 1 44 ? 39.904 25.266 -32.215 1.00 26.41 ? 44 SER A OG 1 ATOM 322 N N . ALA A 1 45 ? 37.977 27.794 -32.443 1.00 26.18 ? 45 ALA A N 1 ATOM 323 C CA . ALA A 1 45 ? 36.514 27.847 -32.316 1.00 25.58 ? 45 ALA A CA 1 ATOM 324 C C . ALA A 1 45 ? 35.913 26.462 -32.087 1.00 26.01 ? 45 ALA A C 1 ATOM 325 O O . ALA A 1 45 ? 34.825 26.329 -31.529 1.00 26.32 ? 45 ALA A O 1 ATOM 326 C CB . ALA A 1 45 ? 35.887 28.499 -33.544 1.00 23.36 ? 45 ALA A CB 1 ATOM 327 N N . THR A 1 46 ? 36.639 25.436 -32.516 1.00 26.93 ? 46 THR A N 1 ATOM 328 C CA . THR A 1 46 ? 36.141 24.060 -32.515 1.00 26.91 ? 46 THR A CA 1 ATOM 329 C C . THR A 1 46 ? 37.067 23.105 -31.746 1.00 26.55 ? 46 THR A C 1 ATOM 330 O O . THR A 1 46 ? 38.231 23.412 -31.494 1.00 25.76 ? 46 THR A O 1 ATOM 331 C CB . THR A 1 46 ? 35.941 23.542 -33.957 1.00 26.83 ? 46 THR A CB 1 ATOM 332 O OG1 . THR A 1 46 ? 37.065 23.915 -34.758 1.00 27.53 ? 46 THR A OG1 1 ATOM 333 C CG2 . THR A 1 46 ? 34.702 24.131 -34.574 1.00 26.15 ? 46 THR A CG2 1 ATOM 334 N N . ILE A 1 47 ? 36.538 21.949 -31.374 1.00 25.87 ? 47 ILE A N 1 ATOM 335 C CA . ILE A 1 47 ? 37.305 20.956 -30.628 1.00 25.68 ? 47 ILE A CA 1 ATOM 336 C C . ILE A 1 47 ? 38.111 20.102 -31.597 1.00 25.68 ? 47 ILE A C 1 ATOM 337 O O . ILE A 1 47 ? 37.553 19.582 -32.566 1.00 26.02 ? 47 ILE A O 1 ATOM 338 C CB . ILE A 1 47 ? 36.352 20.058 -29.828 1.00 25.05 ? 47 ILE A CB 1 ATOM 339 C CG1 . ILE A 1 47 ? 35.583 20.899 -28.808 1.00 25.22 ? 47 ILE A CG1 1 ATOM 340 C CG2 . ILE A 1 47 ? 37.105 18.930 -29.153 1.00 24.55 ? 47 ILE A CG2 1 ATOM 341 C CD1 . ILE A 1 47 ? 34.325 20.222 -28.266 1.00 26.40 ? 47 ILE A CD1 1 ATOM 342 N N . SER A 1 48 ? 39.407 19.948 -31.341 1.00 24.70 ? 48 SER A N 1 ATOM 343 C CA . SER A 1 48 ? 40.266 19.152 -32.225 1.00 24.89 ? 48 SER A CA 1 ATOM 344 C C . SER A 1 48 ? 40.352 17.679 -31.831 1.00 24.97 ? 48 SER A C 1 ATOM 345 O O . SER A 1 48 ? 40.488 17.352 -30.646 1.00 24.73 ? 48 SER A O 1 ATOM 346 C CB . SER A 1 48 ? 41.678 19.728 -32.257 1.00 25.58 ? 48 SER A CB 1 ATOM 347 O OG . SER A 1 48 ? 41.669 21.035 -32.792 1.00 26.30 ? 48 SER A OG 1 ATOM 348 N N . PHE A 1 49 ? 40.283 16.800 -32.832 1.00 24.44 ? 49 PHE A N 1 ATOM 349 C CA . PHE A 1 49 ? 40.555 15.388 -32.630 1.00 23.85 ? 49 PHE A CA 1 ATOM 350 C C . PHE A 1 49 ? 42.047 15.220 -32.654 1.00 24.05 ? 49 PHE A C 1 ATOM 351 O O . PHE A 1 49 ? 42.716 15.770 -33.517 1.00 25.46 ? 49 PHE A O 1 ATOM 352 C CB . PHE A 1 49 ? 39.950 14.525 -33.731 1.00 23.86 ? 49 PHE A CB 1 ATOM 353 C CG . PHE A 1 49 ? 38.455 14.596 -33.819 1.00 24.51 ? 49 PHE A CG 1 ATOM 354 C CD1 . PHE A 1 49 ? 37.678 14.843 -32.698 1.00 24.77 ? 49 PHE A CD1 1 ATOM 355 C CD2 . PHE A 1 49 ? 37.817 14.403 -35.035 1.00 24.23 ? 49 PHE A CD2 1 ATOM 356 C CE1 . PHE A 1 49 ? 36.286 14.910 -32.798 1.00 24.47 ? 49 PHE A CE1 1 ATOM 357 C CE2 . PHE A 1 49 ? 36.434 14.458 -35.133 1.00 23.87 ? 49 PHE A CE2 1 ATOM 358 C CZ . PHE A 1 49 ? 35.671 14.716 -34.016 1.00 23.89 ? 49 PHE A CZ 1 ATOM 359 N N . THR A 1 50 ? 42.571 14.477 -31.693 1.00 23.78 ? 50 THR A N 1 ATOM 360 C CA . THR A 1 50 ? 43.977 14.131 -31.675 1.00 24.12 ? 50 THR A CA 1 ATOM 361 C C . THR A 1 50 ? 44.166 12.625 -31.932 1.00 25.28 ? 50 THR A C 1 ATOM 362 O O . THR A 1 50 ? 45.266 12.086 -31.788 1.00 26.61 ? 50 THR A O 1 ATOM 363 C CB . THR A 1 50 ? 44.636 14.543 -30.343 1.00 24.03 ? 50 THR A CB 1 ATOM 364 O OG1 . THR A 1 50 ? 44.066 13.794 -29.266 1.00 24.38 ? 50 THR A OG1 1 ATOM 365 C CG2 . THR A 1 50 ? 44.424 16.008 -30.080 1.00 24.14 ? 50 THR A CG2 1 ATOM 366 N N . LYS A 1 51 ? 43.087 11.947 -32.308 1.00 25.35 ? 51 LYS A N 1 ATOM 367 C CA . LYS A 1 51 ? 43.152 10.555 -32.757 1.00 25.37 ? 51 LYS A CA 1 ATOM 368 C C . LYS A 1 51 ? 42.148 10.398 -33.878 1.00 24.58 ? 51 LYS A C 1 ATOM 369 O O . LYS A 1 51 ? 41.130 11.089 -33.875 1.00 23.34 ? 51 LYS A O 1 ATOM 370 C CB . LYS A 1 51 ? 42.799 9.580 -31.623 1.00 26.43 ? 51 LYS A CB 1 ATOM 371 C CG . LYS A 1 51 ? 43.831 9.473 -30.503 1.00 27.09 ? 51 LYS A CG 1 ATOM 372 C CD . LYS A 1 51 ? 45.070 8.734 -30.957 1.00 27.59 ? 51 LYS A CD 1 ATOM 373 C CE . LYS A 1 51 ? 45.984 8.450 -29.801 1.00 28.96 ? 51 LYS A CE 1 ATOM 374 N NZ . LYS A 1 51 ? 46.622 9.708 -29.286 1.00 32.84 ? 51 LYS A NZ 1 ATOM 375 N N . PRO A 1 52 ? 42.416 9.483 -34.839 1.00 25.12 ? 52 PRO A N 1 ATOM 376 C CA . PRO A 1 52 ? 41.450 9.260 -35.936 1.00 23.47 ? 52 PRO A CA 1 ATOM 377 C C . PRO A 1 52 ? 40.069 8.950 -35.403 1.00 23.09 ? 52 PRO A C 1 ATOM 378 O O . PRO A 1 52 ? 39.084 9.440 -35.949 1.00 23.60 ? 52 PRO A O 1 ATOM 379 C CB . PRO A 1 52 ? 42.018 8.040 -36.666 1.00 23.52 ? 52 PRO A CB 1 ATOM 380 C CG . PRO A 1 52 ? 43.511 8.109 -36.405 1.00 23.33 ? 52 PRO A CG 1 ATOM 381 C CD . PRO A 1 52 ? 43.653 8.684 -35.017 1.00 24.25 ? 52 PRO A CD 1 ATOM 382 N N . TRP A 1 53 ? 40.011 8.175 -34.321 1.00 22.31 ? 53 TRP A N 1 ATOM 383 C CA . TRP A 1 53 ? 38.750 7.679 -33.754 1.00 22.45 ? 53 TRP A CA 1 ATOM 384 C C . TRP A 1 53 ? 38.190 8.528 -32.635 1.00 23.25 ? 53 TRP A C 1 ATOM 385 O O . TRP A 1 53 ? 37.406 8.039 -31.811 1.00 24.61 ? 53 TRP A O 1 ATOM 386 C CB . TRP A 1 53 ? 38.955 6.241 -33.256 1.00 21.33 ? 53 TRP A CB 1 ATOM 387 C CG . TRP A 1 53 ? 40.244 6.074 -32.479 1.00 21.33 ? 53 TRP A CG 1 ATOM 388 C CD1 . TRP A 1 53 ? 41.494 5.651 -32.960 1.00 21.35 ? 53 TRP A CD1 1 ATOM 389 C CD2 . TRP A 1 53 ? 40.477 6.380 -31.059 1.00 20.46 ? 53 TRP A CD2 1 ATOM 390 N NE1 . TRP A 1 53 ? 42.443 5.661 -31.956 1.00 20.28 ? 53 TRP A NE1 1 ATOM 391 C CE2 . TRP A 1 53 ? 41.899 6.091 -30.797 1.00 20.41 ? 53 TRP A CE2 1 ATOM 392 C CE3 . TRP A 1 53 ? 39.690 6.837 -30.027 1.00 19.61 ? 53 TRP A CE3 1 ATOM 393 C CZ2 . TRP A 1 53 ? 42.455 6.247 -29.546 1.00 20.43 ? 53 TRP A CZ2 1 ATOM 394 C CZ3 . TRP A 1 53 ? 40.273 7.003 -28.771 1.00 20.01 ? 53 TRP A CZ3 1 ATOM 395 C CH2 . TRP A 1 53 ? 41.619 6.707 -28.536 1.00 19.82 ? 53 TRP A CH2 1 ATOM 396 N N . SER A 1 54 ? 38.584 9.795 -32.567 1.00 23.63 ? 54 SER A N 1 ATOM 397 C CA . SER A 1 54 ? 38.213 10.656 -31.435 1.00 25.28 ? 54 SER A CA 1 ATOM 398 C C . SER A 1 54 ? 36.726 11.016 -31.408 1.00 26.70 ? 54 SER A C 1 ATOM 399 O O . SER A 1 54 ? 36.191 11.404 -30.367 1.00 27.54 ? 54 SER A O 1 ATOM 400 C CB . SER A 1 54 ? 39.053 11.936 -31.421 1.00 26.17 ? 54 SER A CB 1 ATOM 401 O OG . SER A 1 54 ? 40.372 11.682 -30.982 1.00 26.24 ? 54 SER A OG 1 ATOM 402 N N . GLN A 1 55 ? 36.061 10.888 -32.552 1.00 27.57 ? 55 GLN A N 1 ATOM 403 C CA . GLN A 1 55 ? 34.623 11.125 -32.628 1.00 27.39 ? 55 GLN A CA 1 ATOM 404 C C . GLN A 1 55 ? 33.831 9.955 -32.032 1.00 27.76 ? 55 GLN A C 1 ATOM 405 O O . GLN A 1 55 ? 32.615 10.045 -31.862 1.00 28.94 ? 55 GLN A O 1 ATOM 406 C CB . GLN A 1 55 ? 34.202 11.395 -34.075 1.00 25.92 ? 55 GLN A CB 1 ATOM 407 C CG . GLN A 1 55 ? 32.746 11.804 -34.228 1.00 25.43 ? 55 GLN A CG 1 ATOM 408 C CD . GLN A 1 55 ? 32.431 12.305 -35.616 1.00 25.82 ? 55 GLN A CD 1 ATOM 409 O OE1 . GLN A 1 55 ? 33.278 12.911 -36.272 1.00 26.22 ? 55 GLN A OE1 1 ATOM 410 N NE2 . GLN A 1 55 ? 31.204 12.065 -36.072 1.00 25.22 ? 55 GLN A NE2 1 ATOM 411 N N . GLY A 1 56 ? 34.520 8.865 -31.707 1.00 27.94 ? 56 GLY A N 1 ATOM 412 C CA . GLY A 1 56 ? 33.859 7.678 -31.153 1.00 30.10 ? 56 GLY A CA 1 ATOM 413 C C . GLY A 1 56 ? 32.873 7.064 -32.129 1.00 30.31 ? 56 GLY A C 1 ATOM 414 O O . GLY A 1 56 ? 33.158 6.971 -33.322 1.00 30.39 ? 56 GLY A O 1 ATOM 415 N N . LYS A 1 57 ? 31.716 6.647 -31.621 1.00 31.41 ? 57 LYS A N 1 ATOM 416 C CA . LYS A 1 57 ? 30.638 6.111 -32.465 1.00 31.38 ? 57 LYS A CA 1 ATOM 417 C C . LYS A 1 57 ? 29.500 7.107 -32.639 1.00 30.25 ? 57 LYS A C 1 ATOM 418 O O . LYS A 1 57 ? 28.375 6.711 -32.934 1.00 31.05 ? 57 LYS A O 1 ATOM 419 C CB . LYS A 1 57 ? 30.069 4.804 -31.890 1.00 32.73 ? 57 LYS A CB 1 ATOM 420 C CG . LYS A 1 57 ? 30.987 3.593 -31.942 1.00 35.19 ? 57 LYS A CG 1 ATOM 421 C CD . LYS A 1 57 ? 31.265 3.103 -33.368 1.00 36.72 ? 57 LYS A CD 1 ATOM 422 C CE . LYS A 1 57 ? 32.200 1.889 -33.313 1.00 37.88 ? 57 LYS A CE 1 ATOM 423 N NZ . LYS A 1 57 ? 32.645 1.438 -34.653 1.00 39.37 ? 57 LYS A NZ 1 ATOM 424 N N . LEU A 1 58 ? 29.779 8.391 -32.439 1.00 29.44 ? 58 LEU A N 1 ATOM 425 C CA . LEU A 1 58 ? 28.769 9.428 -32.645 1.00 30.12 ? 58 LEU A CA 1 ATOM 426 C C . LEU A 1 58 ? 28.636 9.784 -34.117 1.00 30.09 ? 58 LEU A C 1 ATOM 427 O O . LEU A 1 58 ? 29.632 9.917 -34.817 1.00 30.84 ? 58 LEU A O 1 ATOM 428 C CB . LEU A 1 58 ? 29.120 10.695 -31.857 1.00 30.37 ? 58 LEU A CB 1 ATOM 429 C CG . LEU A 1 58 ? 29.033 10.743 -30.326 1.00 30.08 ? 58 LEU A CG 1 ATOM 430 C CD1 . LEU A 1 58 ? 29.224 12.166 -29.900 1.00 28.68 ? 58 LEU A CD1 1 ATOM 431 C CD2 . LEU A 1 58 ? 27.716 10.197 -29.779 1.00 29.95 ? 58 LEU A CD2 1 ATOM 432 N N . SER A 1 59 ? 27.412 9.965 -34.588 1.00 30.90 ? 59 SER A N 1 ATOM 433 C CA . SER A 1 59 ? 27.210 10.456 -35.953 1.00 32.74 ? 59 SER A CA 1 ATOM 434 C C . SER A 1 59 ? 27.754 11.872 -36.062 1.00 32.87 ? 59 SER A C 1 ATOM 435 O O . SER A 1 59 ? 28.048 12.492 -35.043 1.00 32.89 ? 59 SER A O 1 ATOM 436 C CB . SER A 1 59 ? 25.726 10.436 -36.326 1.00 32.80 ? 59 SER A CB 1 ATOM 437 O OG . SER A 1 59 ? 24.989 11.365 -35.554 1.00 32.80 ? 59 SER A OG 1 ATOM 438 N N . ASN A 1 60 ? 27.891 12.388 -37.280 1.00 33.47 ? 60 ASN A N 1 ATOM 439 C CA . ASN A 1 60 ? 28.277 13.786 -37.439 1.00 34.28 ? 60 ASN A CA 1 ATOM 440 C C . ASN A 1 60 ? 27.265 14.725 -36.788 1.00 35.11 ? 60 ASN A C 1 ATOM 441 O O . ASN A 1 60 ? 27.643 15.645 -36.063 1.00 36.16 ? 60 ASN A O 1 ATOM 442 C CB . ASN A 1 60 ? 28.512 14.152 -38.902 1.00 34.43 ? 60 ASN A CB 1 ATOM 443 C CG . ASN A 1 60 ? 29.768 13.511 -39.473 1.00 35.32 ? 60 ASN A CG 1 ATOM 444 O OD1 . ASN A 1 60 ? 30.713 13.201 -38.743 1.00 37.14 ? 60 ASN A OD1 1 ATOM 445 N ND2 . ASN A 1 60 ? 29.787 13.315 -40.784 1.00 33.46 ? 60 ASN A ND2 1 ATOM 446 N N . GLN A 1 61 ? 25.981 14.467 -37.001 1.00 36.82 ? 61 GLN A N 1 ATOM 447 C CA . GLN A 1 61 ? 24.964 15.337 -36.422 1.00 38.82 ? 61 GLN A CA 1 ATOM 448 C C . GLN A 1 61 ? 25.051 15.372 -34.896 1.00 37.07 ? 61 GLN A C 1 ATOM 449 O O . GLN A 1 61 ? 24.968 16.445 -34.306 1.00 39.40 ? 61 GLN A O 1 ATOM 450 C CB . GLN A 1 61 ? 23.545 14.999 -36.917 1.00 42.45 ? 61 GLN A CB 1 ATOM 451 C CG . GLN A 1 61 ? 22.470 15.991 -36.426 1.00 46.75 ? 61 GLN A CG 1 ATOM 452 C CD . GLN A 1 61 ? 21.195 16.005 -37.269 1.00 50.58 ? 61 GLN A CD 1 ATOM 453 O OE1 . GLN A 1 61 ? 20.931 16.967 -37.999 1.00 51.78 ? 61 GLN A OE1 1 ATOM 454 N NE2 . GLN A 1 61 ? 20.392 14.944 -37.159 1.00 50.84 ? 61 GLN A NE2 1 ATOM 455 N N . GLN A 1 62 ? 25.248 14.218 -34.263 1.00 34.67 ? 62 GLN A N 1 ATOM 456 C CA . GLN A 1 62 ? 25.363 14.154 -32.798 1.00 33.41 ? 62 GLN A CA 1 ATOM 457 C C . GLN A 1 62 ? 26.565 14.914 -32.252 1.00 33.01 ? 62 GLN A C 1 ATOM 458 O O . GLN A 1 62 ? 26.472 15.586 -31.222 1.00 31.72 ? 62 GLN A O 1 ATOM 459 C CB . GLN A 1 62 ? 25.474 12.721 -32.324 1.00 34.18 ? 62 GLN A CB 1 ATOM 460 C CG . GLN A 1 62 ? 24.290 11.861 -32.603 1.00 34.44 ? 62 GLN A CG 1 ATOM 461 C CD . GLN A 1 62 ? 24.621 10.437 -32.302 1.00 36.48 ? 62 GLN A CD 1 ATOM 462 O OE1 . GLN A 1 62 ? 24.547 9.999 -31.154 1.00 37.96 ? 62 GLN A OE1 1 ATOM 463 N NE2 . GLN A 1 62 ? 25.032 9.703 -33.322 1.00 36.24 ? 62 GLN A NE2 1 ATOM 464 N N . TRP A 1 63 ? 27.698 14.775 -32.937 1.00 32.94 ? 63 TRP A N 1 ATOM 465 C CA . TRP A 1 63 ? 28.902 15.507 -32.594 1.00 31.58 ? 63 TRP A CA 1 ATOM 466 C C . TRP A 1 63 ? 28.763 17.003 -32.763 1.00 33.53 ? 63 TRP A C 1 ATOM 467 O O . TRP A 1 63 ? 29.270 17.763 -31.931 1.00 32.59 ? 63 TRP A O 1 ATOM 468 C CB . TRP A 1 63 ? 30.087 15.006 -33.405 1.00 29.42 ? 63 TRP A CB 1 ATOM 469 C CG . TRP A 1 63 ? 31.327 15.778 -33.058 1.00 28.48 ? 63 TRP A CG 1 ATOM 470 C CD1 . TRP A 1 63 ? 31.985 16.732 -33.827 1.00 28.00 ? 63 TRP A CD1 1 ATOM 471 C CD2 . TRP A 1 63 ? 32.057 15.739 -31.793 1.00 28.00 ? 63 TRP A CD2 1 ATOM 472 N NE1 . TRP A 1 63 ? 33.063 17.246 -33.155 1.00 27.73 ? 63 TRP A NE1 1 ATOM 473 C CE2 . TRP A 1 63 ? 33.163 16.693 -31.929 1.00 28.05 ? 63 TRP A CE2 1 ATOM 474 C CE3 . TRP A 1 63 ? 31.929 15.015 -30.614 1.00 27.71 ? 63 TRP A CE3 1 ATOM 475 C CZ2 . TRP A 1 63 ? 34.072 16.906 -30.911 1.00 28.04 ? 63 TRP A CZ2 1 ATOM 476 C CZ3 . TRP A 1 63 ? 32.854 15.234 -29.597 1.00 28.01 ? 63 TRP A CZ3 1 ATOM 477 C CH2 . TRP A 1 63 ? 33.900 16.158 -29.741 1.00 28.53 ? 63 TRP A CH2 1 ATOM 478 N N . GLU A 1 64 ? 28.107 17.449 -33.840 1.00 36.02 ? 64 GLU A N 1 ATOM 479 C CA . GLU A 1 64 ? 28.000 18.893 -34.112 1.00 38.51 ? 64 GLU A CA 1 ATOM 480 C C . GLU A 1 64 ? 27.174 19.547 -33.022 1.00 35.51 ? 64 GLU A C 1 ATOM 481 O O . GLU A 1 64 ? 27.494 20.642 -32.559 1.00 34.89 ? 64 GLU A O 1 ATOM 482 C CB . GLU A 1 64 ? 27.406 19.197 -35.497 1.00 43.02 ? 64 GLU A CB 1 ATOM 483 C CG . GLU A 1 64 ? 28.288 18.796 -36.693 1.00 52.11 ? 64 GLU A CG 1 ATOM 484 C CD . GLU A 1 64 ? 29.500 19.713 -36.921 1.00 61.82 ? 64 GLU A CD 1 ATOM 485 O OE1 . GLU A 1 64 ? 30.644 19.198 -36.985 1.00 65.92 ? 64 GLU A OE1 1 ATOM 486 O OE2 . GLU A 1 64 ? 29.315 20.948 -37.047 1.00 69.03 ? 64 GLU A OE2 1 ATOM 487 N N . LYS A 1 65 ? 26.134 18.840 -32.599 1.00 33.92 ? 65 LYS A N 1 ATOM 488 C CA . LYS A 1 65 ? 25.209 19.323 -31.591 1.00 33.75 ? 65 LYS A CA 1 ATOM 489 C C . LYS A 1 65 ? 25.879 19.326 -30.214 1.00 31.29 ? 65 LYS A C 1 ATOM 490 O O . LYS A 1 65 ? 25.591 20.165 -29.365 1.00 31.32 ? 65 LYS A O 1 ATOM 491 C CB . LYS A 1 65 ? 23.948 18.453 -31.594 1.00 36.20 ? 65 LYS A CB 1 ATOM 492 C CG . LYS A 1 65 ? 22.705 19.136 -31.054 1.00 40.16 ? 65 LYS A CG 1 ATOM 493 C CD . LYS A 1 65 ? 21.608 18.123 -30.810 1.00 43.62 ? 65 LYS A CD 1 ATOM 494 C CE . LYS A 1 65 ? 20.905 18.365 -29.476 1.00 46.81 ? 65 LYS A CE 1 ATOM 495 N NZ . LYS A 1 65 ? 20.163 17.129 -29.032 1.00 51.68 ? 65 LYS A NZ 1 ATOM 496 N N . LEU A 1 66 ? 26.788 18.388 -30.012 1.00 29.23 ? 66 LEU A N 1 ATOM 497 C CA . LEU A 1 66 ? 27.530 18.283 -28.767 1.00 28.07 ? 66 LEU A CA 1 ATOM 498 C C . LEU A 1 66 ? 28.646 19.331 -28.669 1.00 28.06 ? 66 LEU A C 1 ATOM 499 O O . LEU A 1 66 ? 28.828 19.961 -27.628 1.00 27.90 ? 66 LEU A O 1 ATOM 500 C CB . LEU A 1 66 ? 28.109 16.880 -28.644 1.00 27.09 ? 66 LEU A CB 1 ATOM 501 C CG . LEU A 1 66 ? 28.830 16.575 -27.350 1.00 26.94 ? 66 LEU A CG 1 ATOM 502 C CD1 . LEU A 1 66 ? 27.832 16.616 -26.201 1.00 26.43 ? 66 LEU A CD1 1 ATOM 503 C CD2 . LEU A 1 66 ? 29.476 15.224 -27.467 1.00 26.32 ? 66 LEU A CD2 1 ATOM 504 N N . GLN A 1 67 ? 29.398 19.508 -29.750 1.00 27.21 ? 67 GLN A N 1 ATOM 505 C CA . GLN A 1 67 ? 30.374 20.567 -29.801 1.00 27.30 ? 67 GLN A CA 1 ATOM 506 C C . GLN A 1 67 ? 29.724 21.916 -29.575 1.00 28.28 ? 67 GLN A C 1 ATOM 507 O O . GLN A 1 67 ? 30.245 22.734 -28.825 1.00 29.57 ? 67 GLN A O 1 ATOM 508 C CB . GLN A 1 67 ? 31.087 20.586 -31.138 1.00 27.03 ? 67 GLN A CB 1 ATOM 509 C CG . GLN A 1 67 ? 32.239 21.576 -31.172 1.00 26.98 ? 67 GLN A CG 1 ATOM 510 C CD . GLN A 1 67 ? 33.024 21.477 -32.432 1.00 26.89 ? 67 GLN A CD 1 ATOM 511 O OE1 . GLN A 1 67 ? 34.254 21.424 -32.416 1.00 28.25 ? 67 GLN A OE1 1 ATOM 512 N NE2 . GLN A 1 67 ? 32.321 21.420 -33.546 1.00 26.91 ? 67 GLN A NE2 1 ATOM 513 N N . HIS A 1 68 ? 28.597 22.151 -30.239 1.00 29.53 ? 68 HIS A N 1 ATOM 514 C CA . HIS A 1 68 ? 27.902 23.430 -30.138 1.00 29.75 ? 68 HIS A CA 1 ATOM 515 C C . HIS A 1 68 ? 27.529 23.737 -28.708 1.00 29.40 ? 68 HIS A C 1 ATOM 516 O O . HIS A 1 68 ? 27.543 24.893 -28.272 1.00 28.63 ? 68 HIS A O 1 ATOM 517 C CB . HIS A 1 68 ? 26.683 23.470 -31.060 1.00 30.23 ? 68 HIS A CB 1 ATOM 518 C CG . HIS A 1 68 ? 25.969 24.797 -31.051 1.00 33.04 ? 68 HIS A CG 1 ATOM 519 N ND1 . HIS A 1 68 ? 24.679 24.929 -30.669 1.00 34.49 ? 68 HIS A ND1 1 ATOM 520 C CD2 . HIS A 1 68 ? 26.425 26.086 -31.348 1.00 33.94 ? 68 HIS A CD2 1 ATOM 521 C CE1 . HIS A 1 68 ? 24.320 26.230 -30.735 1.00 34.25 ? 68 HIS A CE1 1 ATOM 522 N NE2 . HIS A 1 68 ? 25.390 26.937 -31.144 1.00 34.41 ? 68 HIS A NE2 1 ATOM 523 N N . MET A 1 69 ? 27.215 22.695 -27.952 1.00 28.48 ? 69 MET A N 1 ATOM 524 C CA . MET A 1 69 ? 26.856 22.872 -26.570 1.00 27.83 ? 69 MET A CA 1 ATOM 525 C C . MET A 1 69 ? 28.071 23.357 -25.760 1.00 27.60 ? 69 MET A C 1 ATOM 526 O O . MET A 1 69 ? 27.948 24.245 -24.906 1.00 29.43 ? 69 MET A O 1 ATOM 527 C CB . MET A 1 69 ? 26.312 21.575 -26.013 1.00 28.14 ? 69 MET A CB 1 ATOM 528 C CG . MET A 1 69 ? 25.812 21.698 -24.624 1.00 31.16 ? 69 MET A CG 1 ATOM 529 S SD . MET A 1 69 ? 26.250 20.258 -23.657 1.00 39.59 ? 69 MET A SD 1 ATOM 530 C CE . MET A 1 69 ? 28.014 20.474 -23.493 1.00 35.55 ? 69 MET A CE 1 ATOM 531 N N . PHE A 1 70 ? 29.237 22.783 -26.029 1.00 24.68 ? 70 PHE A N 1 ATOM 532 C CA . PHE A 1 70 ? 30.443 23.215 -25.359 1.00 23.23 ? 70 PHE A CA 1 ATOM 533 C C . PHE A 1 70 ? 30.819 24.619 -25.771 1.00 23.01 ? 70 PHE A C 1 ATOM 534 O O . PHE A 1 70 ? 31.220 25.430 -24.920 1.00 23.39 ? 70 PHE A O 1 ATOM 535 C CB . PHE A 1 70 ? 31.605 22.244 -25.600 1.00 23.14 ? 70 PHE A CB 1 ATOM 536 C CG . PHE A 1 70 ? 31.482 20.975 -24.819 1.00 23.46 ? 70 PHE A CG 1 ATOM 537 C CD1 . PHE A 1 70 ? 31.501 21.000 -23.429 1.00 23.69 ? 70 PHE A CD1 1 ATOM 538 C CD2 . PHE A 1 70 ? 31.306 19.756 -25.466 1.00 23.77 ? 70 PHE A CD2 1 ATOM 539 C CE1 . PHE A 1 70 ? 31.357 19.831 -22.700 1.00 24.30 ? 70 PHE A CE1 1 ATOM 540 C CE2 . PHE A 1 70 ? 31.164 18.576 -24.745 1.00 23.87 ? 70 PHE A CE2 1 ATOM 541 C CZ . PHE A 1 70 ? 31.191 18.610 -23.367 1.00 24.62 ? 70 PHE A CZ 1 ATOM 542 N N . GLN A 1 71 ? 30.676 24.914 -27.063 1.00 21.89 ? 71 GLN A N 1 ATOM 543 C CA . GLN A 1 71 ? 31.016 26.229 -27.589 1.00 21.25 ? 71 GLN A CA 1 ATOM 544 C C . GLN A 1 71 ? 30.315 27.326 -26.825 1.00 21.38 ? 71 GLN A C 1 ATOM 545 O O . GLN A 1 71 ? 30.928 28.347 -26.517 1.00 22.36 ? 71 GLN A O 1 ATOM 546 C CB . GLN A 1 71 ? 30.682 26.326 -29.056 1.00 21.22 ? 71 GLN A CB 1 ATOM 547 C CG . GLN A 1 71 ? 31.711 25.634 -29.895 1.00 22.82 ? 71 GLN A CG 1 ATOM 548 C CD . GLN A 1 71 ? 31.312 25.531 -31.329 1.00 22.77 ? 71 GLN A CD 1 ATOM 549 O OE1 . GLN A 1 71 ? 30.124 25.402 -31.643 1.00 23.88 ? 71 GLN A OE1 1 ATOM 550 N NE2 . GLN A 1 71 ? 32.296 25.579 -32.221 1.00 21.43 ? 71 GLN A NE2 1 ATOM 551 N N . VAL A 1 72 ? 29.043 27.093 -26.511 1.00 20.62 ? 72 VAL A N 1 ATOM 552 C CA . VAL A 1 72 ? 28.242 27.986 -25.688 1.00 20.38 ? 72 VAL A CA 1 ATOM 553 C C . VAL A 1 72 ? 28.714 27.937 -24.239 1.00 20.51 ? 72 VAL A C 1 ATOM 554 O O . VAL A 1 72 ? 28.873 28.997 -23.595 1.00 21.46 ? 72 VAL A O 1 ATOM 555 C CB . VAL A 1 72 ? 26.757 27.600 -25.725 1.00 20.74 ? 72 VAL A CB 1 ATOM 556 C CG1 . VAL A 1 72 ? 25.947 28.488 -24.799 1.00 20.80 ? 72 VAL A CG1 1 ATOM 557 C CG2 . VAL A 1 72 ? 26.224 27.657 -27.141 1.00 21.07 ? 72 VAL A CG2 1 ATOM 558 N N . TYR A 1 73 ? 28.931 26.724 -23.719 1.00 19.06 ? 73 TYR A N 1 ATOM 559 C CA . TYR A 1 73 ? 29.444 26.577 -22.349 1.00 18.57 ? 73 TYR A CA 1 ATOM 560 C C . TYR A 1 73 ? 30.710 27.428 -22.090 1.00 17.87 ? 73 TYR A C 1 ATOM 561 O O . TYR A 1 73 ? 30.785 28.147 -21.104 1.00 16.92 ? 73 TYR A O 1 ATOM 562 C CB . TYR A 1 73 ? 29.677 25.099 -21.982 1.00 18.36 ? 73 TYR A CB 1 ATOM 563 C CG . TYR A 1 73 ? 30.683 24.916 -20.870 1.00 17.96 ? 73 TYR A CG 1 ATOM 564 C CD1 . TYR A 1 73 ? 30.344 25.184 -19.536 1.00 17.62 ? 73 TYR A CD1 1 ATOM 565 C CD2 . TYR A 1 73 ? 31.987 24.508 -21.155 1.00 17.65 ? 73 TYR A CD2 1 ATOM 566 C CE1 . TYR A 1 73 ? 31.284 25.041 -18.516 1.00 17.74 ? 73 TYR A CE1 1 ATOM 567 C CE2 . TYR A 1 73 ? 32.930 24.351 -20.148 1.00 17.52 ? 73 TYR A CE2 1 ATOM 568 C CZ . TYR A 1 73 ? 32.575 24.617 -18.831 1.00 17.83 ? 73 TYR A CZ 1 ATOM 569 O OH . TYR A 1 73 ? 33.524 24.470 -17.830 1.00 18.34 ? 73 TYR A OH 1 ATOM 570 N N . ARG A 1 74 ? 31.675 27.361 -22.998 1.00 17.96 ? 74 ARG A N 1 ATOM 571 C CA . ARG A 1 74 ? 32.952 28.049 -22.817 1.00 18.08 ? 74 ARG A CA 1 ATOM 572 C C . ARG A 1 74 ? 32.810 29.563 -22.648 1.00 18.00 ? 74 ARG A C 1 ATOM 573 O O . ARG A 1 74 ? 33.433 30.168 -21.760 1.00 17.42 ? 74 ARG A O 1 ATOM 574 C CB . ARG A 1 74 ? 33.889 27.745 -23.986 1.00 18.34 ? 74 ARG A CB 1 ATOM 575 C CG . ARG A 1 74 ? 35.271 28.258 -23.749 1.00 18.69 ? 74 ARG A CG 1 ATOM 576 C CD . ARG A 1 74 ? 36.226 27.666 -24.701 1.00 20.02 ? 74 ARG A CD 1 ATOM 577 N NE . ARG A 1 74 ? 36.216 28.359 -25.979 1.00 21.30 ? 74 ARG A NE 1 ATOM 578 C CZ . ARG A 1 74 ? 37.212 28.314 -26.856 1.00 22.43 ? 74 ARG A CZ 1 ATOM 579 N NH1 . ARG A 1 74 ? 38.315 27.601 -26.599 1.00 24.13 ? 74 ARG A NH1 1 ATOM 580 N NH2 . ARG A 1 74 ? 37.112 28.985 -27.989 1.00 22.29 ? 74 ARG A NH2 1 ATOM 581 N N . VAL A 1 75 ? 31.993 30.157 -23.515 1.00 17.65 ? 75 VAL A N 1 ATOM 582 C CA . VAL A 1 75 ? 31.732 31.579 -23.498 1.00 17.76 ? 75 VAL A CA 1 ATOM 583 C C . VAL A 1 75 ? 30.951 31.915 -22.226 1.00 18.44 ? 75 VAL A C 1 ATOM 584 O O . VAL A 1 75 ? 31.263 32.872 -21.519 1.00 18.39 ? 75 VAL A O 1 ATOM 585 C CB . VAL A 1 75 ? 30.945 31.997 -24.770 1.00 17.53 ? 75 VAL A CB 1 ATOM 586 C CG1 . VAL A 1 75 ? 30.345 33.390 -24.628 1.00 17.63 ? 75 VAL A CG1 1 ATOM 587 C CG2 . VAL A 1 75 ? 31.841 31.941 -25.983 1.00 17.46 ? 75 VAL A CG2 1 ATOM 588 N N . SER A 1 76 ? 29.947 31.097 -21.934 1.00 19.26 ? 76 SER A N 1 ATOM 589 C CA . SER A 1 76 ? 29.117 31.294 -20.773 1.00 20.11 ? 76 SER A CA 1 ATOM 590 C C . SER A 1 76 ? 29.905 31.189 -19.472 1.00 21.25 ? 76 SER A C 1 ATOM 591 O O . SER A 1 76 ? 29.828 32.085 -18.620 1.00 21.98 ? 76 SER A O 1 ATOM 592 C CB . SER A 1 76 ? 27.978 30.295 -20.798 1.00 20.57 ? 76 SER A CB 1 ATOM 593 O OG . SER A 1 76 ? 27.065 30.660 -21.806 1.00 20.71 ? 76 SER A OG 1 ATOM 594 N N . PHE A 1 77 ? 30.668 30.103 -19.332 1.00 21.65 ? 77 PHE A N 1 ATOM 595 C CA . PHE A 1 77 ? 31.584 29.909 -18.198 1.00 21.73 ? 77 PHE A CA 1 ATOM 596 C C . PHE A 1 77 ? 32.450 31.142 -17.938 1.00 21.45 ? 77 PHE A C 1 ATOM 597 O O . PHE A 1 77 ? 32.504 31.633 -16.815 1.00 21.36 ? 77 PHE A O 1 ATOM 598 C CB . PHE A 1 77 ? 32.458 28.669 -18.426 1.00 21.82 ? 77 PHE A CB 1 ATOM 599 C CG . PHE A 1 77 ? 33.522 28.468 -17.390 1.00 22.02 ? 77 PHE A CG 1 ATOM 600 C CD1 . PHE A 1 77 ? 34.810 28.962 -17.591 1.00 21.93 ? 77 PHE A CD1 1 ATOM 601 C CD2 . PHE A 1 77 ? 33.247 27.761 -16.217 1.00 22.23 ? 77 PHE A CD2 1 ATOM 602 C CE1 . PHE A 1 77 ? 35.796 28.774 -16.627 1.00 22.10 ? 77 PHE A CE1 1 ATOM 603 C CE2 . PHE A 1 77 ? 34.237 27.553 -15.250 1.00 20.85 ? 77 PHE A CE2 1 ATOM 604 C CZ . PHE A 1 77 ? 35.501 28.058 -15.455 1.00 21.25 ? 77 PHE A CZ 1 ATOM 605 N N . THR A 1 78 ? 33.106 31.644 -18.981 1.00 21.46 ? 78 THR A N 1 ATOM 606 C CA . THR A 1 78 ? 33.984 32.806 -18.853 1.00 21.57 ? 78 THR A CA 1 ATOM 607 C C . THR A 1 78 ? 33.246 33.942 -18.192 1.00 22.56 ? 78 THR A C 1 ATOM 608 O O . THR A 1 78 ? 33.746 34.509 -17.225 1.00 24.28 ? 78 THR A O 1 ATOM 609 C CB . THR A 1 78 ? 34.556 33.276 -20.211 1.00 21.15 ? 78 THR A CB 1 ATOM 610 O OG1 . THR A 1 78 ? 35.305 32.209 -20.802 1.00 20.59 ? 78 THR A OG1 1 ATOM 611 C CG2 . THR A 1 78 ? 35.472 34.481 -20.036 1.00 20.58 ? 78 THR A CG2 1 ATOM 612 N N . ARG A 1 79 ? 32.052 34.266 -18.686 1.00 22.72 ? 79 ARG A N 1 ATOM 613 C CA . ARG A 1 79 ? 31.316 35.411 -18.146 1.00 22.47 ? 79 ARG A CA 1 ATOM 614 C C . ARG A 1 79 ? 30.831 35.154 -16.716 1.00 22.61 ? 79 ARG A C 1 ATOM 615 O O . ARG A 1 79 ? 30.873 36.032 -15.865 1.00 21.39 ? 79 ARG A O 1 ATOM 616 C CB . ARG A 1 79 ? 30.149 35.786 -19.055 1.00 21.96 ? 79 ARG A CB 1 ATOM 617 C CG . ARG A 1 79 ? 29.724 37.233 -18.889 1.00 22.88 ? 79 ARG A CG 1 ATOM 618 C CD . ARG A 1 79 ? 28.456 37.552 -19.667 1.00 24.27 ? 79 ARG A CD 1 ATOM 619 N NE . ARG A 1 79 ? 27.233 37.021 -19.047 1.00 25.99 ? 79 ARG A NE 1 ATOM 620 C CZ . ARG A 1 79 ? 26.026 37.078 -19.610 1.00 25.78 ? 79 ARG A CZ 1 ATOM 621 N NH1 . ARG A 1 79 ? 25.873 37.628 -20.798 1.00 25.51 ? 79 ARG A NH1 1 ATOM 622 N NH2 . ARG A 1 79 ? 24.966 36.584 -18.994 1.00 26.42 ? 79 ARG A NH2 1 ATOM 623 N N . ASP A 1 80 ? 30.379 33.932 -16.458 1.00 24.11 ? 80 ASP A N 1 ATOM 624 C CA . ASP A 1 80 ? 29.815 33.592 -15.158 1.00 25.00 ? 80 ASP A CA 1 ATOM 625 C C . ASP A 1 80 ? 30.853 33.700 -14.046 1.00 24.98 ? 80 ASP A C 1 ATOM 626 O O . ASP A 1 80 ? 30.544 34.236 -12.983 1.00 26.18 ? 80 ASP A O 1 ATOM 627 C CB . ASP A 1 80 ? 29.151 32.213 -15.194 1.00 26.48 ? 80 ASP A CB 1 ATOM 628 C CG . ASP A 1 80 ? 27.767 32.230 -15.901 1.00 29.34 ? 80 ASP A CG 1 ATOM 629 O OD1 . ASP A 1 80 ? 27.318 33.304 -16.404 1.00 29.41 ? 80 ASP A OD1 1 ATOM 630 O OD2 . ASP A 1 80 ? 27.116 31.153 -15.939 1.00 29.11 ? 80 ASP A OD2 1 ATOM 631 N N . ILE A 1 81 ? 32.081 33.238 -14.302 1.00 23.76 ? 81 ILE A N 1 ATOM 632 C CA . ILE A 1 81 ? 33.186 33.413 -13.357 1.00 23.40 ? 81 ILE A CA 1 ATOM 633 C C . ILE A 1 81 ? 33.370 34.907 -13.044 1.00 23.73 ? 81 ILE A C 1 ATOM 634 O O . ILE A 1 81 ? 33.386 35.306 -11.881 1.00 23.05 ? 81 ILE A O 1 ATOM 635 C CB . ILE A 1 81 ? 34.520 32.755 -13.872 1.00 23.43 ? 81 ILE A CB 1 ATOM 636 C CG1 . ILE A 1 81 ? 34.446 31.211 -13.862 1.00 22.52 ? 81 ILE A CG1 1 ATOM 637 C CG2 . ILE A 1 81 ? 35.741 33.234 -13.070 1.00 23.41 ? 81 ILE A CG2 1 ATOM 638 C CD1 . ILE A 1 81 ? 33.751 30.583 -12.647 1.00 21.26 ? 81 ILE A CD1 1 ATOM 639 N N . GLN A 1 82 ? 33.468 35.716 -14.099 1.00 24.31 ? 82 GLN A N 1 ATOM 640 C CA . GLN A 1 82 ? 33.579 37.176 -14.006 1.00 24.76 ? 82 GLN A CA 1 ATOM 641 C C . GLN A 1 82 ? 32.460 37.817 -13.178 1.00 25.68 ? 82 GLN A C 1 ATOM 642 O O . GLN A 1 82 ? 32.722 38.725 -12.384 1.00 27.55 ? 82 GLN A O 1 ATOM 643 C CB . GLN A 1 82 ? 33.633 37.802 -15.407 1.00 24.66 ? 82 GLN A CB 1 ATOM 644 C CG . GLN A 1 82 ? 34.947 37.556 -16.135 1.00 25.81 ? 82 GLN A CG 1 ATOM 645 C CD . GLN A 1 82 ? 34.890 37.791 -17.651 1.00 26.79 ? 82 GLN A CD 1 ATOM 646 O OE1 . GLN A 1 82 ? 33.817 37.813 -18.263 1.00 27.97 ? 82 GLN A OE1 1 ATOM 647 N NE2 . GLN A 1 82 ? 36.066 37.939 -18.265 1.00 26.39 ? 82 GLN A NE2 1 ATOM 648 N N . GLU A 1 83 ? 31.220 37.352 -13.347 1.00 24.94 ? 83 GLU A N 1 ATOM 649 C CA . GLU A 1 83 ? 30.102 37.915 -12.583 1.00 23.58 ? 83 GLU A CA 1 ATOM 650 C C . GLU A 1 83 ? 30.129 37.422 -11.161 1.00 23.94 ? 83 GLU A C 1 ATOM 651 O O . GLU A 1 83 ? 29.728 38.139 -10.241 1.00 24.96 ? 83 GLU A O 1 ATOM 652 C CB . GLU A 1 83 ? 28.743 37.628 -13.227 1.00 22.73 ? 83 GLU A CB 1 ATOM 653 C CG . GLU A 1 83 ? 28.523 38.354 -14.554 1.00 21.85 ? 83 GLU A CG 1 ATOM 654 C CD . GLU A 1 83 ? 28.744 39.851 -14.445 1.00 21.49 ? 83 GLU A CD 1 ATOM 655 O OE1 . GLU A 1 83 ? 29.482 40.390 -15.283 1.00 21.24 ? 83 GLU A OE1 1 ATOM 656 O OE2 . GLU A 1 83 ? 28.199 40.485 -13.514 1.00 21.06 ? 83 GLU A OE2 1 ATOM 657 N N . LEU A 1 84 ? 30.612 36.202 -10.971 1.00 23.45 ? 84 LEU A N 1 ATOM 658 C CA . LEU A 1 84 ? 30.813 35.698 -9.623 1.00 23.88 ? 84 LEU A CA 1 ATOM 659 C C . LEU A 1 84 ? 31.882 36.518 -8.870 1.00 24.25 ? 84 LEU A C 1 ATOM 660 O O . LEU A 1 84 ? 31.683 36.883 -7.716 1.00 24.23 ? 84 LEU A O 1 ATOM 661 C CB . LEU A 1 84 ? 31.124 34.195 -9.648 1.00 23.08 ? 84 LEU A CB 1 ATOM 662 C CG . LEU A 1 84 ? 29.903 33.348 -10.071 1.00 22.37 ? 84 LEU A CG 1 ATOM 663 C CD1 . LEU A 1 84 ? 30.269 31.916 -10.412 1.00 21.11 ? 84 LEU A CD1 1 ATOM 664 C CD2 . LEU A 1 84 ? 28.800 33.387 -9.004 1.00 22.68 ? 84 LEU A CD2 1 ATOM 665 N N . VAL A 1 85 ? 32.982 36.849 -9.545 1.00 24.05 ? 85 VAL A N 1 ATOM 666 C CA . VAL A 1 85 ? 34.073 37.609 -8.936 1.00 24.28 ? 85 VAL A CA 1 ATOM 667 C C . VAL A 1 85 ? 33.548 38.965 -8.478 1.00 25.05 ? 85 VAL A C 1 ATOM 668 O O . VAL A 1 85 ? 33.904 39.439 -7.393 1.00 25.43 ? 85 VAL A O 1 ATOM 669 C CB . VAL A 1 85 ? 35.251 37.787 -9.923 1.00 24.19 ? 85 VAL A CB 1 ATOM 670 C CG1 . VAL A 1 85 ? 36.349 38.674 -9.356 1.00 23.13 ? 85 VAL A CG1 1 ATOM 671 C CG2 . VAL A 1 85 ? 35.808 36.441 -10.311 1.00 24.54 ? 85 VAL A CG2 1 ATOM 672 N N . LYS A 1 86 ? 32.697 39.564 -9.313 1.00 25.18 ? 86 LYS A N 1 ATOM 673 C CA . LYS A 1 86 ? 31.965 40.782 -8.983 1.00 25.56 ? 86 LYS A CA 1 ATOM 674 C C . LYS A 1 86 ? 31.065 40.602 -7.773 1.00 27.15 ? 86 LYS A C 1 ATOM 675 O O . LYS A 1 86 ? 31.004 41.477 -6.916 1.00 30.01 ? 86 LYS A O 1 ATOM 676 C CB . LYS A 1 86 ? 31.096 41.220 -10.160 1.00 25.15 ? 86 LYS A CB 1 ATOM 677 C CG . LYS A 1 86 ? 31.864 41.768 -11.326 1.00 24.01 ? 86 LYS A CG 1 ATOM 678 C CD . LYS A 1 86 ? 30.939 42.127 -12.435 1.00 22.66 ? 86 LYS A CD 1 ATOM 679 C CE . LYS A 1 86 ? 31.717 42.434 -13.674 1.00 22.25 ? 86 LYS A CE 1 ATOM 680 N NZ . LYS A 1 86 ? 30.750 42.784 -14.713 1.00 22.55 ? 86 LYS A NZ 1 ATOM 681 N N . MET A 1 87 ? 30.358 39.479 -7.709 1.00 27.33 ? 87 MET A N 1 ATOM 682 C CA . MET A 1 87 ? 29.423 39.219 -6.624 1.00 28.74 ? 87 MET A CA 1 ATOM 683 C C . MET A 1 87 ? 30.120 39.026 -5.280 1.00 30.85 ? 87 MET A C 1 ATOM 684 O O . MET A 1 87 ? 29.545 39.301 -4.234 1.00 32.49 ? 87 MET A O 1 ATOM 685 C CB . MET A 1 87 ? 28.612 37.973 -6.948 1.00 28.58 ? 87 MET A CB 1 ATOM 686 C CG . MET A 1 87 ? 27.292 37.845 -6.217 1.00 27.97 ? 87 MET A CG 1 ATOM 687 S SD . MET A 1 87 ? 26.372 36.365 -6.711 1.00 27.04 ? 87 MET A SD 1 ATOM 688 C CE . MET A 1 87 ? 25.798 36.797 -8.352 1.00 25.80 ? 87 MET A CE 1 ATOM 689 N N . MET A 1 88 ? 31.352 38.535 -5.305 1.00 32.97 ? 88 MET A N 1 ATOM 690 C CA . MET A 1 88 ? 32.064 38.217 -4.071 1.00 35.56 ? 88 MET A CA 1 ATOM 691 C C . MET A 1 88 ? 32.924 39.362 -3.590 1.00 38.65 ? 88 MET A C 1 ATOM 692 O O . MET A 1 88 ? 33.077 39.550 -2.385 1.00 39.50 ? 88 MET A O 1 ATOM 693 C CB . MET A 1 88 ? 32.933 36.971 -4.238 1.00 34.01 ? 88 MET A CB 1 ATOM 694 C CG . MET A 1 88 ? 32.166 35.694 -4.443 1.00 34.46 ? 88 MET A CG 1 ATOM 695 S SD . MET A 1 88 ? 30.792 35.503 -3.294 1.00 38.57 ? 88 MET A SD 1 ATOM 696 C CE . MET A 1 88 ? 29.430 35.785 -4.395 1.00 38.09 ? 88 MET A CE 1 ATOM 697 N N . SER A 1 89 ? 33.483 40.122 -4.534 1.00 41.71 ? 89 SER A N 1 ATOM 698 C CA . SER A 1 89 ? 34.437 41.192 -4.222 1.00 44.47 ? 89 SER A CA 1 ATOM 699 C C . SER A 1 89 ? 33.967 42.070 -3.058 1.00 45.97 ? 89 SER A C 1 ATOM 700 O O . SER A 1 89 ? 32.773 42.369 -2.952 1.00 43.89 ? 89 SER A O 1 ATOM 701 C CB . SER A 1 89 ? 34.725 42.057 -5.453 1.00 44.12 ? 89 SER A CB 1 ATOM 702 O OG . SER A 1 89 ? 33.623 42.888 -5.746 1.00 42.51 ? 89 SER A OG 1 ATOM 703 N N . PRO A 1 90 ? 34.913 42.502 -2.196 1.00 48.55 ? 90 PRO A N 1 ATOM 704 C CA . PRO A 1 90 ? 36.364 42.353 -2.377 1.00 47.59 ? 90 PRO A CA 1 ATOM 705 C C . PRO A 1 90 ? 36.943 41.093 -1.734 1.00 48.73 ? 90 PRO A C 1 ATOM 706 O O . PRO A 1 90 ? 38.163 40.984 -1.588 1.00 47.99 ? 90 PRO A O 1 ATOM 707 C CB . PRO A 1 90 ? 36.922 43.605 -1.701 1.00 45.96 ? 90 PRO A CB 1 ATOM 708 C CG . PRO A 1 90 ? 35.812 44.103 -0.783 1.00 46.67 ? 90 PRO A CG 1 ATOM 709 C CD . PRO A 1 90 ? 34.611 43.207 -0.941 1.00 46.83 ? 90 PRO A CD 1 ATOM 710 N N . LYS A 1 91 ? 36.069 40.155 -1.373 1.00 48.97 ? 91 LYS A N 1 ATOM 711 C CA . LYS A 1 91 ? 36.471 38.897 -0.753 1.00 50.30 ? 91 LYS A CA 1 ATOM 712 C C . LYS A 1 91 ? 37.450 38.126 -1.638 1.00 50.69 ? 91 LYS A C 1 ATOM 713 O O . LYS A 1 91 ? 38.481 37.654 -1.157 1.00 54.27 ? 91 LYS A O 1 ATOM 714 C CB . LYS A 1 91 ? 35.234 38.042 -0.413 1.00 53.95 ? 91 LYS A CB 1 ATOM 715 C CG . LYS A 1 91 ? 35.524 36.640 0.169 1.00 56.89 ? 91 LYS A CG 1 ATOM 716 C CD . LYS A 1 91 ? 35.773 36.653 1.678 1.00 56.44 ? 91 LYS A CD 1 ATOM 717 C CE . LYS A 1 91 ? 36.642 35.471 2.088 1.00 58.31 ? 91 LYS A CE 1 ATOM 718 N NZ . LYS A 1 91 ? 36.733 35.316 3.574 1.00 60.46 ? 91 LYS A NZ 1 ATOM 719 N N . GLU A 1 92 ? 37.136 38.000 -2.925 1.00 48.65 ? 92 GLU A N 1 ATOM 720 C CA . GLU A 1 92 ? 38.026 37.296 -3.844 1.00 48.76 ? 92 GLU A CA 1 ATOM 721 C C . GLU A 1 92 ? 38.380 38.164 -5.040 1.00 48.54 ? 92 GLU A C 1 ATOM 722 O O . GLU A 1 92 ? 37.578 38.989 -5.465 1.00 51.94 ? 92 GLU A O 1 ATOM 723 C CB . GLU A 1 92 ? 37.424 35.953 -4.271 1.00 50.53 ? 92 GLU A CB 1 ATOM 724 C CG . GLU A 1 92 ? 37.293 34.921 -3.126 1.00 51.06 ? 92 GLU A CG 1 ATOM 725 C CD . GLU A 1 92 ? 38.632 34.546 -2.466 1.00 52.45 ? 92 GLU A CD 1 ATOM 726 O OE1 . GLU A 1 92 ? 39.615 34.288 -3.192 1.00 52.81 ? 92 GLU A OE1 1 ATOM 727 O OE2 . GLU A 1 92 ? 38.699 34.502 -1.215 1.00 53.51 ? 92 GLU A OE2 1 ATOM 728 N N . ASP A 1 93 ? 39.584 37.980 -5.573 1.00 46.79 ? 93 ASP A N 1 ATOM 729 C CA . ASP A 1 93 ? 40.122 38.891 -6.576 1.00 46.19 ? 93 ASP A CA 1 ATOM 730 C C . ASP A 1 93 ? 41.101 38.201 -7.549 1.00 40.73 ? 93 ASP A C 1 ATOM 731 O O . ASP A 1 93 ? 41.646 37.153 -7.250 1.00 37.97 ? 93 ASP A O 1 ATOM 732 C CB . ASP A 1 93 ? 40.780 40.088 -5.863 1.00 52.77 ? 93 ASP A CB 1 ATOM 733 C CG . ASP A 1 93 ? 41.285 41.166 -6.833 1.00 61.41 ? 93 ASP A CG 1 ATOM 734 O OD1 . ASP A 1 93 ? 40.556 41.536 -7.793 1.00 62.84 ? 93 ASP A OD1 1 ATOM 735 O OD2 . ASP A 1 93 ? 42.424 41.649 -6.620 1.00 64.61 ? 93 ASP A OD2 1 ATOM 736 N N . TYR A 1 94 ? 41.307 38.792 -8.722 1.00 37.37 ? 94 TYR A N 1 ATOM 737 C CA . TYR A 1 94 ? 42.228 38.242 -9.709 1.00 35.76 ? 94 TYR A CA 1 ATOM 738 C C . TYR A 1 94 ? 43.671 38.395 -9.224 1.00 35.40 ? 94 TYR A C 1 ATOM 739 O O . TYR A 1 94 ? 43.934 39.225 -8.357 1.00 36.61 ? 94 TYR A O 1 ATOM 740 C CB . TYR A 1 94 ? 42.053 38.956 -11.049 1.00 34.37 ? 94 TYR A CB 1 ATOM 741 C CG . TYR A 1 94 ? 40.650 38.929 -11.589 1.00 33.92 ? 94 TYR A CG 1 ATOM 742 C CD1 . TYR A 1 94 ? 39.840 40.054 -11.532 1.00 34.10 ? 94 TYR A CD1 1 ATOM 743 C CD2 . TYR A 1 94 ? 40.128 37.776 -12.162 1.00 33.74 ? 94 TYR A CD2 1 ATOM 744 C CE1 . TYR A 1 94 ? 38.547 40.030 -12.037 1.00 33.63 ? 94 TYR A CE1 1 ATOM 745 C CE2 . TYR A 1 94 ? 38.832 37.739 -12.661 1.00 32.77 ? 94 TYR A CE2 1 ATOM 746 C CZ . TYR A 1 94 ? 38.048 38.867 -12.599 1.00 33.60 ? 94 TYR A CZ 1 ATOM 747 O OH . TYR A 1 94 ? 36.757 38.824 -13.103 1.00 34.94 ? 94 TYR A OH 1 ATOM 748 N N . PRO A 1 95 ? 44.612 37.587 -9.754 1.00 34.38 ? 95 PRO A N 1 ATOM 749 C CA . PRO A 1 95 ? 44.467 36.456 -10.683 1.00 33.39 ? 95 PRO A CA 1 ATOM 750 C C . PRO A 1 95 ? 43.681 35.280 -10.091 1.00 32.75 ? 95 PRO A C 1 ATOM 751 O O . PRO A 1 95 ? 43.751 35.036 -8.887 1.00 32.91 ? 95 PRO A O 1 ATOM 752 C CB . PRO A 1 95 ? 45.916 36.035 -10.951 1.00 32.09 ? 95 PRO A CB 1 ATOM 753 C CG . PRO A 1 95 ? 46.685 36.579 -9.789 1.00 32.45 ? 95 PRO A CG 1 ATOM 754 C CD . PRO A 1 95 ? 46.031 37.879 -9.489 1.00 33.51 ? 95 PRO A CD 1 ATOM 755 N N . ILE A 1 96 ? 42.943 34.572 -10.947 1.00 31.55 ? 96 ILE A N 1 ATOM 756 C CA . ILE A 1 96 ? 42.171 33.399 -10.545 1.00 31.09 ? 96 ILE A CA 1 ATOM 757 C C . ILE A 1 96 ? 42.452 32.214 -11.478 1.00 32.27 ? 96 ILE A C 1 ATOM 758 O O . ILE A 1 96 ? 42.622 32.397 -12.688 1.00 32.50 ? 96 ILE A O 1 ATOM 759 C CB . ILE A 1 96 ? 40.650 33.717 -10.518 1.00 29.85 ? 96 ILE A CB 1 ATOM 760 C CG1 . ILE A 1 96 ? 40.318 34.618 -9.323 1.00 29.37 ? 96 ILE A CG1 1 ATOM 761 C CG2 . ILE A 1 96 ? 39.820 32.444 -10.460 1.00 27.81 ? 96 ILE A CG2 1 ATOM 762 C CD1 . ILE A 1 96 ? 39.048 35.400 -9.465 1.00 27.93 ? 96 ILE A CD1 1 ATOM 763 N N . GLU A 1 97 ? 42.502 31.010 -10.898 1.00 33.06 ? 97 GLU A N 1 ATOM 764 C CA . GLU A 1 97 ? 42.646 29.754 -11.641 1.00 31.94 ? 97 GLU A CA 1 ATOM 765 C C . GLU A 1 97 ? 41.537 28.776 -11.330 1.00 30.03 ? 97 GLU A C 1 ATOM 766 O O . GLU A 1 97 ? 41.450 28.270 -10.207 1.00 31.55 ? 97 GLU A O 1 ATOM 767 C CB . GLU A 1 97 ? 43.949 29.064 -11.271 1.00 35.00 ? 97 GLU A CB 1 ATOM 768 C CG . GLU A 1 97 ? 45.116 29.473 -12.094 1.00 37.38 ? 97 GLU A CG 1 ATOM 769 C CD . GLU A 1 97 ? 44.912 29.208 -13.570 1.00 40.31 ? 97 GLU A CD 1 ATOM 770 O OE1 . GLU A 1 97 ? 45.285 30.124 -14.342 1.00 41.45 ? 97 GLU A OE1 1 ATOM 771 O OE2 . GLU A 1 97 ? 44.399 28.108 -13.949 1.00 39.38 ? 97 GLU A OE2 1 ATOM 772 N N . ILE A 1 98 ? 40.702 28.494 -12.320 1.00 26.72 ? 98 ILE A N 1 ATOM 773 C CA . ILE A 1 98 ? 39.721 27.433 -12.180 1.00 25.70 ? 98 ILE A CA 1 ATOM 774 C C . ILE A 1 98 ? 40.201 26.244 -12.992 1.00 25.46 ? 98 ILE A C 1 ATOM 775 O O . ILE A 1 98 ? 40.691 26.401 -14.120 1.00 25.31 ? 98 ILE A O 1 ATOM 776 C CB . ILE A 1 98 ? 38.292 27.819 -12.690 1.00 25.41 ? 98 ILE A CB 1 ATOM 777 C CG1 . ILE A 1 98 ? 37.927 29.285 -12.381 1.00 24.44 ? 98 ILE A CG1 1 ATOM 778 C CG2 . ILE A 1 98 ? 37.248 26.814 -12.188 1.00 24.20 ? 98 ILE A CG2 1 ATOM 779 C CD1 . ILE A 1 98 ? 37.615 29.586 -10.957 1.00 24.04 ? 98 ILE A CD1 1 ATOM 780 N N . GLN A 1 99 ? 40.070 25.059 -12.401 1.00 24.51 ? 99 GLN A N 1 ATOM 781 C CA . GLN A 1 99 ? 40.277 23.816 -13.113 1.00 23.32 ? 99 GLN A CA 1 ATOM 782 C C . GLN A 1 99 ? 39.045 22.957 -12.930 1.00 22.56 ? 99 GLN A C 1 ATOM 783 O O . GLN A 1 99 ? 38.435 22.953 -11.859 1.00 21.45 ? 99 GLN A O 1 ATOM 784 C CB . GLN A 1 99 ? 41.492 23.074 -12.584 1.00 23.81 ? 99 GLN A CB 1 ATOM 785 C CG . GLN A 1 99 ? 42.822 23.608 -13.047 1.00 24.52 ? 99 GLN A CG 1 ATOM 786 C CD . GLN A 1 99 ? 43.916 23.344 -12.022 1.00 26.32 ? 99 GLN A CD 1 ATOM 787 O OE1 . GLN A 1 99 ? 44.045 24.081 -11.033 1.00 28.51 ? 99 GLN A OE1 1 ATOM 788 N NE2 . GLN A 1 99 ? 44.705 22.293 -12.243 1.00 25.62 ? 99 GLN A NE2 1 ATOM 789 N N . LEU A 1 100 ? 38.681 22.250 -13.996 1.00 22.08 ? 100 LEU A N 1 ATOM 790 C CA . LEU A 1 100 ? 37.625 21.264 -13.970 1.00 21.35 ? 100 LEU A CA 1 ATOM 791 C C . LEU A 1 100 ? 38.174 19.922 -14.379 1.00 21.16 ? 100 LEU A C 1 ATOM 792 O O . LEU A 1 100 ? 39.011 19.823 -15.271 1.00 20.75 ? 100 LEU A O 1 ATOM 793 C CB . LEU A 1 100 ? 36.524 21.641 -14.947 1.00 22.00 ? 100 LEU A CB 1 ATOM 794 C CG . LEU A 1 100 ? 35.272 22.344 -14.436 1.00 22.81 ? 100 LEU A CG 1 ATOM 795 C CD1 . LEU A 1 100 ? 35.537 23.804 -14.124 1.00 23.21 ? 100 LEU A CD1 1 ATOM 796 C CD2 . LEU A 1 100 ? 34.188 22.221 -15.489 1.00 23.32 ? 100 LEU A CD2 1 ATOM 797 N N . SER A 1 101 ? 37.672 18.877 -13.743 1.00 21.41 ? 101 SER A N 1 ATOM 798 C CA . SER A 1 101 ? 38.038 17.527 -14.111 1.00 21.09 ? 101 SER A CA 1 ATOM 799 C C . SER A 1 101 ? 36.766 16.709 -14.200 1.00 21.31 ? 101 SER A C 1 ATOM 800 O O . SER A 1 101 ? 36.190 16.328 -13.189 1.00 22.15 ? 101 SER A O 1 ATOM 801 C CB . SER A 1 101 ? 38.992 16.958 -13.073 1.00 21.17 ? 101 SER A CB 1 ATOM 802 O OG . SER A 1 101 ? 39.353 15.644 -13.393 1.00 21.47 ? 101 SER A OG 1 ATOM 803 N N . ALA A 1 102 ? 36.313 16.455 -15.420 1.00 21.86 ? 102 ALA A N 1 ATOM 804 C CA . ALA A 1 102 ? 35.031 15.796 -15.629 1.00 22.59 ? 102 ALA A CA 1 ATOM 805 C C . ALA A 1 102 ? 35.188 14.574 -16.522 1.00 24.26 ? 102 ALA A C 1 ATOM 806 O O . ALA A 1 102 ? 36.103 14.510 -17.356 1.00 24.86 ? 102 ALA A O 1 ATOM 807 C CB . ALA A 1 102 ? 34.031 16.760 -16.223 1.00 21.32 ? 102 ALA A CB 1 ATOM 808 N N . GLY A 1 103 ? 34.289 13.609 -16.335 1.00 25.09 ? 103 GLY A N 1 ATOM 809 C CA . GLY A 1 103 ? 34.302 12.381 -17.100 1.00 26.48 ? 103 GLY A CA 1 ATOM 810 C C . GLY A 1 103 ? 33.718 11.238 -16.305 1.00 28.93 ? 103 GLY A C 1 ATOM 811 O O . GLY A 1 103 ? 33.003 11.447 -15.313 1.00 28.03 ? 103 GLY A O 1 ATOM 812 N N . CYS A 1 104 ? 34.038 10.026 -16.748 1.00 31.64 ? 104 CYS A N 1 ATOM 813 C CA . CYS A 1 104 ? 33.488 8.793 -16.185 1.00 33.86 ? 104 CYS A CA 1 ATOM 814 C C . CYS A 1 104 ? 34.555 7.690 -16.110 1.00 35.07 ? 104 CYS A C 1 ATOM 815 O O . CYS A 1 104 ? 35.536 7.707 -16.858 1.00 34.79 ? 104 CYS A O 1 ATOM 816 C CB . CYS A 1 104 ? 32.265 8.350 -17.000 1.00 34.49 ? 104 CYS A CB 1 ATOM 817 S SG . CYS A 1 104 ? 32.463 8.486 -18.812 1.00 40.31 ? 104 CYS A SG 1 ATOM 818 N N . GLU A 1 105 ? 34.391 6.757 -15.179 1.00 38.05 ? 105 GLU A N 1 ATOM 819 C CA . GLU A 1 105 ? 35.272 5.590 -15.113 1.00 41.36 ? 105 GLU A CA 1 ATOM 820 C C . GLU A 1 105 ? 34.472 4.383 -15.556 1.00 42.86 ? 105 GLU A C 1 ATOM 821 O O . GLU A 1 105 ? 33.383 4.138 -15.020 1.00 43.83 ? 105 GLU A O 1 ATOM 822 C CB . GLU A 1 105 ? 35.813 5.397 -13.702 1.00 43.02 ? 105 GLU A CB 1 ATOM 823 C CG . GLU A 1 105 ? 36.958 4.401 -13.603 1.00 46.98 ? 105 GLU A CG 1 ATOM 824 C CD . GLU A 1 105 ? 37.707 4.497 -12.269 1.00 51.40 ? 105 GLU A CD 1 ATOM 825 O OE1 . GLU A 1 105 ? 37.841 5.624 -11.726 1.00 53.56 ? 105 GLU A OE1 1 ATOM 826 O OE2 . GLU A 1 105 ? 38.165 3.444 -11.764 1.00 52.04 ? 105 GLU A OE2 1 ATOM 827 N N . MET A 1 106 ? 34.986 3.656 -16.552 1.00 44.96 ? 106 MET A N 1 ATOM 828 C CA . MET A 1 106 ? 34.252 2.524 -17.154 1.00 46.36 ? 106 MET A CA 1 ATOM 829 C C . MET A 1 106 ? 34.611 1.201 -16.497 1.00 46.64 ? 106 MET A C 1 ATOM 830 O O . MET A 1 106 ? 35.788 0.899 -16.295 1.00 47.07 ? 106 MET A O 1 ATOM 831 C CB . MET A 1 106 ? 34.486 2.439 -18.663 1.00 45.62 ? 106 MET A CB 1 ATOM 832 C CG . MET A 1 106 ? 34.156 3.715 -19.423 1.00 47.68 ? 106 MET A CG 1 ATOM 833 S SD . MET A 1 106 ? 32.433 4.264 -19.306 1.00 51.72 ? 106 MET A SD 1 ATOM 834 C CE . MET A 1 106 ? 31.623 3.328 -20.596 1.00 45.44 ? 106 MET A CE 1 ATOM 835 N N . TYR A 1 107 ? 33.585 0.423 -16.166 1.00 49.45 ? 107 TYR A N 1 ATOM 836 C CA . TYR A 1 107 ? 33.754 -0.846 -15.457 1.00 53.82 ? 107 TYR A CA 1 ATOM 837 C C . TYR A 1 107 ? 33.227 -2.020 -16.295 1.00 57.56 ? 107 TYR A C 1 ATOM 838 O O . TYR A 1 107 ? 32.524 -1.795 -17.285 1.00 57.72 ? 107 TYR A O 1 ATOM 839 C CB . TYR A 1 107 ? 33.057 -0.787 -14.086 1.00 50.25 ? 107 TYR A CB 1 ATOM 840 C CG . TYR A 1 107 ? 33.589 0.285 -13.158 1.00 48.38 ? 107 TYR A CG 1 ATOM 841 C CD1 . TYR A 1 107 ? 34.878 0.201 -12.609 1.00 48.05 ? 107 TYR A CD1 1 ATOM 842 C CD2 . TYR A 1 107 ? 32.798 1.382 -12.816 1.00 48.62 ? 107 TYR A CD2 1 ATOM 843 C CE1 . TYR A 1 107 ? 35.366 1.198 -11.748 1.00 46.34 ? 107 TYR A CE1 1 ATOM 844 C CE2 . TYR A 1 107 ? 33.269 2.380 -11.963 1.00 46.74 ? 107 TYR A CE2 1 ATOM 845 C CZ . TYR A 1 107 ? 34.549 2.285 -11.433 1.00 47.56 ? 107 TYR A CZ 1 ATOM 846 O OH . TYR A 1 107 ? 34.991 3.290 -10.594 1.00 47.45 ? 107 TYR A OH 1 ATOM 847 N N . PRO A 1 108 ? 33.558 -3.275 -15.903 1.00 64.07 ? 108 PRO A N 1 ATOM 848 C CA . PRO A 1 108 ? 33.050 -4.446 -16.637 1.00 64.53 ? 108 PRO A CA 1 ATOM 849 C C . PRO A 1 108 ? 31.531 -4.519 -16.579 1.00 64.31 ? 108 PRO A C 1 ATOM 850 O O . PRO A 1 108 ? 30.914 -3.998 -15.644 1.00 65.30 ? 108 PRO A O 1 ATOM 851 C CB . PRO A 1 108 ? 33.647 -5.638 -15.883 1.00 64.72 ? 108 PRO A CB 1 ATOM 852 C CG . PRO A 1 108 ? 34.729 -5.076 -15.031 1.00 66.53 ? 108 PRO A CG 1 ATOM 853 C CD . PRO A 1 108 ? 34.329 -3.678 -14.711 1.00 64.39 ? 108 PRO A CD 1 ATOM 854 N N . GLY A 1 109 ? 30.937 -5.174 -17.567 1.00 63.71 ? 109 GLY A N 1 ATOM 855 C CA . GLY A 1 109 ? 29.498 -5.099 -17.762 1.00 63.78 ? 109 GLY A CA 1 ATOM 856 C C . GLY A 1 109 ? 29.194 -3.740 -18.358 1.00 62.61 ? 109 GLY A C 1 ATOM 857 O O . GLY A 1 109 ? 30.000 -3.181 -19.107 1.00 62.83 ? 109 GLY A O 1 ATOM 858 N N . ASN A 1 110 ? 28.035 -3.195 -18.030 1.00 60.60 ? 110 ASN A N 1 ATOM 859 C CA . ASN A 1 110 ? 27.710 -1.865 -18.508 1.00 60.59 ? 110 ASN A CA 1 ATOM 860 C C . ASN A 1 110 ? 27.683 -0.862 -17.367 1.00 57.57 ? 110 ASN A C 1 ATOM 861 O O . ASN A 1 110 ? 26.936 0.124 -17.409 1.00 59.29 ? 110 ASN A O 1 ATOM 862 C CB . ASN A 1 110 ? 26.401 -1.867 -19.315 1.00 63.20 ? 110 ASN A CB 1 ATOM 863 C CG . ASN A 1 110 ? 26.606 -2.293 -20.767 1.00 66.75 ? 110 ASN A CG 1 ATOM 864 O OD1 . ASN A 1 110 ? 25.645 -2.589 -21.480 1.00 67.61 ? 110 ASN A OD1 1 ATOM 865 N ND2 . ASN A 1 110 ? 27.866 -2.323 -21.212 1.00 70.87 ? 110 ASN A ND2 1 ATOM 866 N N . ALA A 1 111 ? 28.507 -1.123 -16.351 1.00 51.88 ? 111 ALA A N 1 ATOM 867 C CA . ALA A 1 111 ? 28.599 -0.243 -15.186 1.00 49.83 ? 111 ALA A CA 1 ATOM 868 C C . ALA A 1 111 ? 29.614 0.881 -15.422 1.00 47.55 ? 111 ALA A C 1 ATOM 869 O O . ALA A 1 111 ? 30.627 0.690 -16.110 1.00 45.44 ? 111 ALA A O 1 ATOM 870 C CB . ALA A 1 111 ? 28.946 -1.038 -13.920 1.00 47.92 ? 111 ALA A CB 1 ATOM 871 N N . SER A 1 112 ? 29.312 2.055 -14.868 1.00 43.85 ? 112 SER A N 1 ATOM 872 C CA . SER A 1 112 ? 30.241 3.178 -14.856 1.00 41.22 ? 112 SER A CA 1 ATOM 873 C C . SER A 1 112 ? 29.967 4.130 -13.694 1.00 39.39 ? 112 SER A C 1 ATOM 874 O O . SER A 1 112 ? 29.073 3.913 -12.884 1.00 38.16 ? 112 SER A O 1 ATOM 875 C CB . SER A 1 112 ? 30.215 3.932 -16.186 1.00 41.10 ? 112 SER A CB 1 ATOM 876 O OG . SER A 1 112 ? 28.934 4.469 -16.436 1.00 41.51 ? 112 SER A OG 1 ATOM 877 N N . GLU A 1 113 ? 30.760 5.187 -13.625 1.00 39.29 ? 113 GLU A N 1 ATOM 878 C CA . GLU A 1 113 ? 30.657 6.171 -12.574 1.00 36.74 ? 113 GLU A CA 1 ATOM 879 C C . GLU A 1 113 ? 31.208 7.460 -13.153 1.00 33.22 ? 113 GLU A C 1 ATOM 880 O O . GLU A 1 113 ? 32.317 7.461 -13.680 1.00 33.43 ? 113 GLU A O 1 ATOM 881 C CB . GLU A 1 113 ? 31.502 5.716 -11.402 1.00 41.15 ? 113 GLU A CB 1 ATOM 882 C CG . GLU A 1 113 ? 31.431 6.582 -10.180 1.00 47.29 ? 113 GLU A CG 1 ATOM 883 C CD . GLU A 1 113 ? 32.070 5.909 -8.977 1.00 53.09 ? 113 GLU A CD 1 ATOM 884 O OE1 . GLU A 1 113 ? 32.636 4.791 -9.140 1.00 49.94 ? 113 GLU A OE1 1 ATOM 885 O OE2 . GLU A 1 113 ? 31.996 6.504 -7.871 1.00 57.69 ? 113 GLU A OE2 1 ATOM 886 N N . SER A 1 114 ? 30.427 8.535 -13.083 1.00 28.15 ? 114 SER A N 1 ATOM 887 C CA . SER A 1 114 ? 30.816 9.828 -13.641 1.00 25.24 ? 114 SER A CA 1 ATOM 888 C C . SER A 1 114 ? 31.200 10.800 -12.524 1.00 24.80 ? 114 SER A C 1 ATOM 889 O O . SER A 1 114 ? 30.771 10.640 -11.381 1.00 26.04 ? 114 SER A O 1 ATOM 890 C CB . SER A 1 114 ? 29.658 10.414 -14.455 1.00 24.66 ? 114 SER A CB 1 ATOM 891 O OG . SER A 1 114 ? 29.171 9.502 -15.429 1.00 23.99 ? 114 SER A OG 1 ATOM 892 N N . PHE A 1 115 ? 31.995 11.816 -12.843 1.00 23.07 ? 115 PHE A N 1 ATOM 893 C CA . PHE A 1 115 ? 32.395 12.819 -11.859 1.00 21.32 ? 115 PHE A CA 1 ATOM 894 C C . PHE A 1 115 ? 32.517 14.181 -12.524 1.00 21.37 ? 115 PHE A C 1 ATOM 895 O O . PHE A 1 115 ? 32.658 14.284 -13.746 1.00 22.00 ? 115 PHE A O 1 ATOM 896 C CB . PHE A 1 115 ? 33.729 12.439 -11.235 1.00 21.02 ? 115 PHE A CB 1 ATOM 897 C CG . PHE A 1 115 ? 34.767 12.055 -12.245 1.00 21.99 ? 115 PHE A CG 1 ATOM 898 C CD1 . PHE A 1 115 ? 35.652 13.016 -12.764 1.00 22.24 ? 115 PHE A CD1 1 ATOM 899 C CD2 . PHE A 1 115 ? 34.853 10.742 -12.709 1.00 21.65 ? 115 PHE A CD2 1 ATOM 900 C CE1 . PHE A 1 115 ? 36.606 12.673 -13.725 1.00 21.85 ? 115 PHE A CE1 1 ATOM 901 C CE2 . PHE A 1 115 ? 35.803 10.390 -13.677 1.00 22.25 ? 115 PHE A CE2 1 ATOM 902 C CZ . PHE A 1 115 ? 36.682 11.355 -14.188 1.00 21.97 ? 115 PHE A CZ 1 ATOM 903 N N . LEU A 1 116 ? 32.441 15.232 -11.720 1.00 20.34 ? 116 LEU A N 1 ATOM 904 C CA . LEU A 1 116 ? 32.710 16.566 -12.204 1.00 19.48 ? 116 LEU A CA 1 ATOM 905 C C . LEU A 1 116 ? 33.264 17.360 -11.028 1.00 19.27 ? 116 LEU A C 1 ATOM 906 O O . LEU A 1 116 ? 32.519 17.792 -10.159 1.00 20.10 ? 116 LEU A O 1 ATOM 907 C CB . LEU A 1 116 ? 31.449 17.212 -12.778 1.00 18.28 ? 116 LEU A CB 1 ATOM 908 C CG . LEU A 1 116 ? 31.617 18.405 -13.732 1.00 18.19 ? 116 LEU A CG 1 ATOM 909 C CD1 . LEU A 1 116 ? 30.252 18.955 -14.160 1.00 18.13 ? 116 LEU A CD1 1 ATOM 910 C CD2 . LEU A 1 116 ? 32.456 19.521 -13.156 1.00 17.93 ? 116 LEU A CD2 1 ATOM 911 N N . HIS A 1 117 ? 34.575 17.538 -11.006 1.00 18.86 ? 117 HIS A N 1 ATOM 912 C CA . HIS A 1 117 ? 35.242 18.147 -9.873 1.00 19.14 ? 117 HIS A CA 1 ATOM 913 C C . HIS A 1 117 ? 35.772 19.481 -10.261 1.00 19.42 ? 117 HIS A C 1 ATOM 914 O O . HIS A 1 117 ? 36.238 19.649 -11.391 1.00 20.02 ? 117 HIS A O 1 ATOM 915 C CB . HIS A 1 117 ? 36.365 17.247 -9.399 1.00 18.99 ? 117 HIS A CB 1 ATOM 916 C CG . HIS A 1 117 ? 35.884 15.994 -8.720 1.00 19.47 ? 117 HIS A CG 1 ATOM 917 N ND1 . HIS A 1 117 ? 36.703 15.184 -8.037 1.00 19.72 ? 117 HIS A ND1 1 ATOM 918 C CD2 . HIS A 1 117 ? 34.613 15.432 -8.630 1.00 19.79 ? 117 HIS A CD2 1 ATOM 919 C CE1 . HIS A 1 117 ? 36.008 14.138 -7.560 1.00 19.81 ? 117 HIS A CE1 1 ATOM 920 N NE2 . HIS A 1 117 ? 34.726 14.296 -7.915 1.00 20.06 ? 117 HIS A NE2 1 ATOM 921 N N . VAL A 1 118 ? 35.697 20.444 -9.347 1.00 18.82 ? 118 VAL A N 1 ATOM 922 C CA . VAL A 1 118 ? 36.137 21.794 -9.652 1.00 19.68 ? 118 VAL A CA 1 ATOM 923 C C . VAL A 1 118 ? 37.168 22.287 -8.648 1.00 20.40 ? 118 VAL A C 1 ATOM 924 O O . VAL A 1 118 ? 36.982 22.170 -7.432 1.00 20.97 ? 118 VAL A O 1 ATOM 925 C CB . VAL A 1 118 ? 34.961 22.770 -9.696 1.00 20.09 ? 118 VAL A CB 1 ATOM 926 C CG1 . VAL A 1 118 ? 35.451 24.201 -9.945 1.00 19.44 ? 118 VAL A CG1 1 ATOM 927 C CG2 . VAL A 1 118 ? 33.964 22.344 -10.771 1.00 20.43 ? 118 VAL A CG2 1 ATOM 928 N N . ALA A 1 119 ? 38.253 22.848 -9.166 1.00 20.59 ? 119 ALA A N 1 ATOM 929 C CA . ALA A 1 119 ? 39.324 23.387 -8.331 1.00 20.36 ? 119 ALA A CA 1 ATOM 930 C C . ALA A 1 119 ? 39.452 24.898 -8.492 1.00 20.30 ? 119 ALA A C 1 ATOM 931 O O . ALA A 1 119 ? 39.352 25.434 -9.591 1.00 20.71 ? 119 ALA A O 1 ATOM 932 C CB . ALA A 1 119 ? 40.633 22.702 -8.654 1.00 20.43 ? 119 ALA A CB 1 ATOM 933 N N . PHE A 1 120 ? 39.666 25.574 -7.376 1.00 21.03 ? 120 PHE A N 1 ATOM 934 C CA . PHE A 1 120 ? 39.842 27.026 -7.337 1.00 21.31 ? 120 PHE A CA 1 ATOM 935 C C . PHE A 1 120 ? 41.209 27.317 -6.723 1.00 21.97 ? 120 PHE A C 1 ATOM 936 O O . PHE A 1 120 ? 41.513 26.869 -5.608 1.00 22.58 ? 120 PHE A O 1 ATOM 937 C CB . PHE A 1 120 ? 38.731 27.613 -6.492 1.00 20.96 ? 120 PHE A CB 1 ATOM 938 C CG . PHE A 1 120 ? 38.772 29.094 -6.350 1.00 21.83 ? 120 PHE A CG 1 ATOM 939 C CD1 . PHE A 1 120 ? 38.278 29.924 -7.364 1.00 21.82 ? 120 PHE A CD1 1 ATOM 940 C CD2 . PHE A 1 120 ? 39.232 29.675 -5.167 1.00 21.94 ? 120 PHE A CD2 1 ATOM 941 C CE1 . PHE A 1 120 ? 38.277 31.319 -7.223 1.00 21.46 ? 120 PHE A CE1 1 ATOM 942 C CE2 . PHE A 1 120 ? 39.227 31.074 -5.014 1.00 21.95 ? 120 PHE A CE2 1 ATOM 943 C CZ . PHE A 1 120 ? 38.748 31.895 -6.045 1.00 21.23 ? 120 PHE A CZ 1 ATOM 944 N N . GLN A 1 121 ? 42.050 28.035 -7.459 1.00 22.10 ? 121 GLN A N 1 ATOM 945 C CA . GLN A 1 121 ? 43.416 28.328 -7.008 1.00 22.16 ? 121 GLN A CA 1 ATOM 946 C C . GLN A 1 121 ? 44.172 27.055 -6.612 1.00 22.84 ? 121 GLN A C 1 ATOM 947 O O . GLN A 1 121 ? 44.976 27.058 -5.677 1.00 23.43 ? 121 GLN A O 1 ATOM 948 C CB . GLN A 1 121 ? 43.416 29.335 -5.860 1.00 21.47 ? 121 GLN A CB 1 ATOM 949 C CG . GLN A 1 121 ? 42.561 30.576 -6.110 1.00 22.39 ? 121 GLN A CG 1 ATOM 950 C CD . GLN A 1 121 ? 43.204 31.609 -7.038 1.00 22.54 ? 121 GLN A CD 1 ATOM 951 O OE1 . GLN A 1 121 ? 43.578 31.313 -8.178 1.00 22.50 ? 121 GLN A OE1 1 ATOM 952 N NE2 . GLN A 1 121 ? 43.300 32.840 -6.554 1.00 22.28 ? 121 GLN A NE2 1 ATOM 953 N N . GLY A 1 122 ? 43.900 25.966 -7.329 1.00 22.62 ? 122 GLY A N 1 ATOM 954 C CA . GLY A 1 122 ? 44.612 24.719 -7.123 1.00 22.68 ? 122 GLY A CA 1 ATOM 955 C C . GLY A 1 122 ? 44.069 23.846 -6.007 1.00 23.14 ? 122 GLY A C 1 ATOM 956 O O . GLY A 1 122 ? 44.632 22.787 -5.733 1.00 23.81 ? 122 GLY A O 1 ATOM 957 N N . LYS A 1 123 ? 42.989 24.270 -5.354 1.00 22.62 ? 123 LYS A N 1 ATOM 958 C CA . LYS A 1 123 ? 42.371 23.435 -4.321 1.00 22.43 ? 123 LYS A CA 1 ATOM 959 C C . LYS A 1 123 ? 41.020 22.964 -4.809 1.00 22.19 ? 123 LYS A C 1 ATOM 960 O O . LYS A 1 123 ? 40.224 23.760 -5.299 1.00 23.36 ? 123 LYS A O 1 ATOM 961 C CB . LYS A 1 123 ? 42.227 24.179 -2.992 1.00 22.62 ? 123 LYS A CB 1 ATOM 962 C CG . LYS A 1 123 ? 43.546 24.609 -2.358 1.00 23.69 ? 123 LYS A CG 1 ATOM 963 N N . TYR A 1 124 ? 40.779 21.662 -4.701 1.00 21.60 ? 124 TYR A N 1 ATOM 964 C CA . TYR A 1 124 ? 39.484 21.056 -5.036 1.00 20.65 ? 124 TYR A CA 1 ATOM 965 C C . TYR A 1 124 ? 38.437 21.577 -4.053 1.00 20.36 ? 124 TYR A C 1 ATOM 966 O O . TYR A 1 124 ? 38.622 21.459 -2.846 1.00 20.85 ? 124 TYR A O 1 ATOM 967 C CB . TYR A 1 124 ? 39.624 19.531 -4.940 1.00 19.94 ? 124 TYR A CB 1 ATOM 968 C CG . TYR A 1 124 ? 38.354 18.722 -5.039 1.00 19.58 ? 124 TYR A CG 1 ATOM 969 C CD1 . TYR A 1 124 ? 37.393 19.016 -6.005 1.00 20.04 ? 124 TYR A CD1 1 ATOM 970 C CD2 . TYR A 1 124 ? 38.131 17.623 -4.195 1.00 19.14 ? 124 TYR A CD2 1 ATOM 971 C CE1 . TYR A 1 124 ? 36.217 18.268 -6.106 1.00 20.07 ? 124 TYR A CE1 1 ATOM 972 C CE2 . TYR A 1 124 ? 36.973 16.854 -4.300 1.00 19.32 ? 124 TYR A CE2 1 ATOM 973 C CZ . TYR A 1 124 ? 36.020 17.188 -5.268 1.00 19.78 ? 124 TYR A CZ 1 ATOM 974 O OH . TYR A 1 124 ? 34.862 16.479 -5.416 1.00 19.39 ? 124 TYR A OH 1 ATOM 975 N N . VAL A 1 125 ? 37.363 22.175 -4.560 1.00 19.61 ? 125 VAL A N 1 ATOM 976 C CA . VAL A 1 125 ? 36.363 22.830 -3.695 1.00 19.42 ? 125 VAL A CA 1 ATOM 977 C C . VAL A 1 125 ? 34.914 22.444 -3.977 1.00 19.87 ? 125 VAL A C 1 ATOM 978 O O . VAL A 1 125 ? 34.090 22.385 -3.064 1.00 20.63 ? 125 VAL A O 1 ATOM 979 C CB . VAL A 1 125 ? 36.464 24.396 -3.733 1.00 19.08 ? 125 VAL A CB 1 ATOM 980 C CG1 . VAL A 1 125 ? 37.624 24.888 -2.898 1.00 19.07 ? 125 VAL A CG1 1 ATOM 981 C CG2 . VAL A 1 125 ? 36.586 24.920 -5.150 1.00 18.68 ? 125 VAL A CG2 1 ATOM 982 N N . VAL A 1 126 ? 34.605 22.189 -5.242 1.00 20.16 ? 126 VAL A N 1 ATOM 983 C CA . VAL A 1 126 ? 33.236 22.006 -5.677 1.00 20.63 ? 126 VAL A CA 1 ATOM 984 C C . VAL A 1 126 ? 33.130 20.789 -6.568 1.00 21.91 ? 126 VAL A C 1 ATOM 985 O O . VAL A 1 126 ? 34.107 20.406 -7.227 1.00 22.64 ? 126 VAL A O 1 ATOM 986 C CB . VAL A 1 126 ? 32.757 23.240 -6.457 1.00 20.72 ? 126 VAL A CB 1 ATOM 987 C CG1 . VAL A 1 126 ? 31.457 22.949 -7.182 1.00 20.33 ? 126 VAL A CG1 1 ATOM 988 C CG2 . VAL A 1 126 ? 32.603 24.449 -5.506 1.00 20.84 ? 126 VAL A CG2 1 ATOM 989 N N . ARG A 1 127 ? 31.945 20.181 -6.588 1.00 22.70 ? 127 ARG A N 1 ATOM 990 C CA . ARG A 1 127 ? 31.654 19.101 -7.529 1.00 23.28 ? 127 ARG A CA 1 ATOM 991 C C . ARG A 1 127 ? 30.191 19.083 -7.923 1.00 23.57 ? 127 ARG A C 1 ATOM 992 O O . ARG A 1 127 ? 29.345 19.641 -7.218 1.00 23.56 ? 127 ARG A O 1 ATOM 993 C CB . ARG A 1 127 ? 32.008 17.754 -6.918 1.00 24.08 ? 127 ARG A CB 1 ATOM 994 C CG . ARG A 1 127 ? 31.044 17.321 -5.864 1.00 24.84 ? 127 ARG A CG 1 ATOM 995 C CD . ARG A 1 127 ? 31.383 15.974 -5.348 1.00 25.78 ? 127 ARG A CD 1 ATOM 996 N NE . ARG A 1 127 ? 30.443 15.600 -4.301 1.00 28.20 ? 127 ARG A NE 1 ATOM 997 C CZ . ARG A 1 127 ? 30.421 14.408 -3.726 1.00 29.26 ? 127 ARG A CZ 1 ATOM 998 N NH1 . ARG A 1 127 ? 31.286 13.470 -4.106 1.00 29.81 ? 127 ARG A NH1 1 ATOM 999 N NH2 . ARG A 1 127 ? 29.529 14.151 -2.785 1.00 28.94 ? 127 ARG A NH2 1 ATOM 1000 N N . PHE A 1 128 ? 29.889 18.443 -9.047 1.00 23.29 ? 128 PHE A N 1 ATOM 1001 C CA . PHE A 1 128 ? 28.503 18.126 -9.329 1.00 24.21 ? 128 PHE A CA 1 ATOM 1002 C C . PHE A 1 128 ? 28.243 16.752 -8.781 1.00 25.30 ? 128 PHE A C 1 ATOM 1003 O O . PHE A 1 128 ? 29.005 15.815 -9.027 1.00 26.81 ? 128 PHE A O 1 ATOM 1004 C CB . PHE A 1 128 ? 28.148 18.168 -10.816 1.00 23.94 ? 128 PHE A CB 1 ATOM 1005 C CG . PHE A 1 128 ? 26.670 18.342 -11.065 1.00 23.58 ? 128 PHE A CG 1 ATOM 1006 C CD1 . PHE A 1 128 ? 26.122 19.619 -11.201 1.00 23.68 ? 128 PHE A CD1 1 ATOM 1007 C CD2 . PHE A 1 128 ? 25.826 17.242 -11.127 1.00 23.37 ? 128 PHE A CD2 1 ATOM 1008 C CE1 . PHE A 1 128 ? 24.762 19.802 -11.401 1.00 23.60 ? 128 PHE A CE1 1 ATOM 1009 C CE2 . PHE A 1 128 ? 24.472 17.407 -11.317 1.00 23.90 ? 128 PHE A CE2 1 ATOM 1010 C CZ . PHE A 1 128 ? 23.933 18.697 -11.464 1.00 24.23 ? 128 PHE A CZ 1 ATOM 1011 N N . TRP A 1 129 ? 27.170 16.643 -8.015 1.00 25.90 ? 129 TRP A N 1 ATOM 1012 C CA . TRP A 1 129 ? 26.811 15.395 -7.401 1.00 27.13 ? 129 TRP A CA 1 ATOM 1013 C C . TRP A 1 129 ? 25.322 15.281 -7.356 1.00 26.01 ? 129 TRP A C 1 ATOM 1014 O O . TRP A 1 129 ? 24.643 16.149 -6.820 1.00 26.57 ? 129 TRP A O 1 ATOM 1015 C CB . TRP A 1 129 ? 27.400 15.321 -5.995 1.00 29.89 ? 129 TRP A CB 1 ATOM 1016 C CG . TRP A 1 129 ? 27.253 13.956 -5.388 1.00 31.47 ? 129 TRP A CG 1 ATOM 1017 C CD1 . TRP A 1 129 ? 26.416 13.575 -4.342 1.00 31.34 ? 129 TRP A CD1 1 ATOM 1018 C CD2 . TRP A 1 129 ? 27.939 12.728 -5.805 1.00 31.95 ? 129 TRP A CD2 1 ATOM 1019 N NE1 . TRP A 1 129 ? 26.551 12.234 -4.077 1.00 32.24 ? 129 TRP A NE1 1 ATOM 1020 C CE2 . TRP A 1 129 ? 27.450 11.665 -4.917 1.00 32.64 ? 129 TRP A CE2 1 ATOM 1021 C CE3 . TRP A 1 129 ? 28.889 12.414 -6.782 1.00 33.81 ? 129 TRP A CE3 1 ATOM 1022 C CZ2 . TRP A 1 129 ? 27.898 10.348 -5.024 1.00 33.88 ? 129 TRP A CZ2 1 ATOM 1023 C CZ3 . TRP A 1 129 ? 29.342 11.083 -6.884 1.00 34.48 ? 129 TRP A CZ3 1 ATOM 1024 C CH2 . TRP A 1 129 ? 28.854 10.073 -6.026 1.00 34.66 ? 129 TRP A CH2 1 ATOM 1025 N N . GLY A 1 130 ? 24.806 14.209 -7.938 1.00 25.18 ? 130 GLY A N 1 ATOM 1026 C CA . GLY A 1 130 ? 23.381 13.938 -7.934 1.00 25.32 ? 130 GLY A CA 1 ATOM 1027 C C . GLY A 1 130 ? 22.602 14.862 -8.839 1.00 24.74 ? 130 GLY A C 1 ATOM 1028 O O . GLY A 1 130 ? 22.441 14.601 -10.031 1.00 24.57 ? 130 GLY A O 1 ATOM 1029 N N . THR A 1 131 ? 22.154 15.962 -8.256 1.00 24.82 ? 131 THR A N 1 ATOM 1030 C CA . THR A 1 131 ? 21.216 16.884 -8.885 1.00 24.80 ? 131 THR A CA 1 ATOM 1031 C C . THR A 1 131 ? 21.680 18.334 -8.829 1.00 24.47 ? 131 THR A C 1 ATOM 1032 O O . THR A 1 131 ? 21.057 19.218 -9.425 1.00 23.46 ? 131 THR A O 1 ATOM 1033 C CB . THR A 1 131 ? 19.833 16.706 -8.232 1.00 24.17 ? 131 THR A CB 1 ATOM 1034 O OG1 . THR A 1 131 ? 19.018 16.028 -9.175 1.00 25.64 ? 131 THR A OG1 1 ATOM 1035 C CG2 . THR A 1 131 ? 19.156 18.020 -7.833 1.00 24.13 ? 131 THR A CG2 1 ATOM 1036 N N . SER A 1 132 ? 22.790 18.561 -8.131 1.00 23.94 ? 132 SER A N 1 ATOM 1037 C CA . SER A 1 132 ? 23.226 19.920 -7.844 1.00 24.69 ? 132 SER A CA 1 ATOM 1038 C C . SER A 1 132 ? 24.737 20.064 -7.627 1.00 23.81 ? 132 SER A C 1 ATOM 1039 O O . SER A 1 132 ? 25.485 19.084 -7.568 1.00 23.59 ? 132 SER A O 1 ATOM 1040 C CB . SER A 1 132 ? 22.480 20.440 -6.617 1.00 24.73 ? 132 SER A CB 1 ATOM 1041 O OG . SER A 1 132 ? 22.710 19.563 -5.536 1.00 25.52 ? 132 SER A OG 1 ATOM 1042 N N . TRP A 1 133 ? 25.171 21.311 -7.535 1.00 22.64 ? 133 TRP A N 1 ATOM 1043 C CA . TRP A 1 133 ? 26.508 21.610 -7.107 1.00 22.97 ? 133 TRP A CA 1 ATOM 1044 C C . TRP A 1 133 ? 26.541 21.580 -5.615 1.00 23.50 ? 133 TRP A C 1 ATOM 1045 O O . TRP A 1 133 ? 25.587 22.010 -4.957 1.00 24.56 ? 133 TRP A O 1 ATOM 1046 C CB . TRP A 1 133 ? 26.901 22.989 -7.586 1.00 22.02 ? 133 TRP A CB 1 ATOM 1047 C CG . TRP A 1 133 ? 26.801 23.150 -9.073 1.00 21.91 ? 133 TRP A CG 1 ATOM 1048 C CD1 . TRP A 1 133 ? 25.786 23.774 -9.793 1.00 22.46 ? 133 TRP A CD1 1 ATOM 1049 C CD2 . TRP A 1 133 ? 27.759 22.684 -10.085 1.00 21.80 ? 133 TRP A CD2 1 ATOM 1050 N NE1 . TRP A 1 133 ? 26.048 23.741 -11.144 1.00 22.11 ? 133 TRP A NE1 1 ATOM 1051 C CE2 . TRP A 1 133 ? 27.211 23.095 -11.389 1.00 21.87 ? 133 TRP A CE2 1 ATOM 1052 C CE3 . TRP A 1 133 ? 28.966 21.993 -10.045 1.00 21.57 ? 133 TRP A CE3 1 ATOM 1053 C CZ2 . TRP A 1 133 ? 27.862 22.815 -12.580 1.00 21.22 ? 133 TRP A CZ2 1 ATOM 1054 C CZ3 . TRP A 1 133 ? 29.612 21.719 -11.252 1.00 21.80 ? 133 TRP A CZ3 1 ATOM 1055 C CH2 . TRP A 1 133 ? 29.068 22.122 -12.489 1.00 21.70 ? 133 TRP A CH2 1 ATOM 1056 N N . GLN A 1 134 ? 27.627 21.060 -5.061 1.00 23.86 ? 134 GLN A N 1 ATOM 1057 C CA . GLN A 1 134 ? 27.884 21.194 -3.633 1.00 25.15 ? 134 GLN A CA 1 ATOM 1058 C C . GLN A 1 134 ? 29.375 21.362 -3.357 1.00 24.72 ? 134 GLN A C 1 ATOM 1059 O O . GLN A 1 134 ? 30.211 20.930 -4.168 1.00 25.55 ? 134 GLN A O 1 ATOM 1060 C CB . GLN A 1 134 ? 27.320 20.007 -2.876 1.00 26.07 ? 134 GLN A CB 1 ATOM 1061 C CG . GLN A 1 134 ? 27.706 18.711 -3.458 1.00 28.97 ? 134 GLN A CG 1 ATOM 1062 C CD . GLN A 1 134 ? 27.369 17.567 -2.544 1.00 32.26 ? 134 GLN A CD 1 ATOM 1063 O OE1 . GLN A 1 134 ? 28.205 16.676 -2.308 1.00 33.42 ? 134 GLN A OE1 1 ATOM 1064 N NE2 . GLN A 1 134 ? 26.141 17.575 -2.014 1.00 31.22 ? 134 GLN A NE2 1 ATOM 1065 N N . THR A 1 135 ? 29.713 22.007 -2.238 1.00 23.59 ? 135 THR A N 1 ATOM 1066 C CA . THR A 1 135 ? 31.122 22.157 -1.873 1.00 23.50 ? 135 THR A CA 1 ATOM 1067 C C . THR A 1 135 ? 31.574 20.876 -1.200 1.00 22.82 ? 135 THR A C 1 ATOM 1068 O O . THR A 1 135 ? 30.794 20.214 -0.541 1.00 23.18 ? 135 THR A O 1 ATOM 1069 C CB . THR A 1 135 ? 31.391 23.353 -0.950 1.00 23.39 ? 135 THR A CB 1 ATOM 1070 O OG1 . THR A 1 135 ? 30.564 23.245 0.204 1.00 24.91 ? 135 THR A OG1 1 ATOM 1071 C CG2 . THR A 1 135 ? 31.081 24.663 -1.637 1.00 23.20 ? 135 THR A CG2 1 ATOM 1072 N N . VAL A 1 136 ? 32.821 20.505 -1.408 1.00 22.41 ? 136 VAL A N 1 ATOM 1073 C CA . VAL A 1 136 ? 33.405 19.355 -0.724 1.00 22.81 ? 136 VAL A CA 1 ATOM 1074 C C . VAL A 1 136 ? 34.008 19.788 0.619 1.00 23.19 ? 136 VAL A C 1 ATOM 1075 O O . VAL A 1 136 ? 34.281 20.972 0.836 1.00 23.21 ? 136 VAL A O 1 ATOM 1076 C CB . VAL A 1 136 ? 34.495 18.715 -1.600 1.00 22.82 ? 136 VAL A CB 1 ATOM 1077 C CG1 . VAL A 1 136 ? 33.887 18.315 -2.938 1.00 22.87 ? 136 VAL A CG1 1 ATOM 1078 C CG2 . VAL A 1 136 ? 35.696 19.670 -1.799 1.00 20.75 ? 136 VAL A CG2 1 ATOM 1079 N N . PRO A 1 137 ? 34.237 18.834 1.522 1.00 23.58 ? 137 PRO A N 1 ATOM 1080 C CA . PRO A 1 137 ? 34.802 19.185 2.841 1.00 23.26 ? 137 PRO A CA 1 ATOM 1081 C C . PRO A 1 137 ? 36.115 19.952 2.710 1.00 23.30 ? 137 PRO A C 1 ATOM 1082 O O . PRO A 1 137 ? 36.957 19.580 1.888 1.00 23.50 ? 137 PRO A O 1 ATOM 1083 C CB . PRO A 1 137 ? 35.058 17.830 3.473 1.00 22.91 ? 137 PRO A CB 1 ATOM 1084 C CG . PRO A 1 137 ? 34.024 16.943 2.843 1.00 24.02 ? 137 PRO A CG 1 ATOM 1085 C CD . PRO A 1 137 ? 33.947 17.396 1.407 1.00 23.44 ? 137 PRO A CD 1 ATOM 1086 N N . GLY A 1 138 ? 36.267 21.022 3.495 1.00 22.89 ? 138 GLY A N 1 ATOM 1087 C CA . GLY A 1 138 ? 37.479 21.837 3.481 1.00 23.06 ? 138 GLY A CA 1 ATOM 1088 C C . GLY A 1 138 ? 37.349 23.162 2.738 1.00 24.46 ? 138 GLY A C 1 ATOM 1089 O O . GLY A 1 138 ? 38.256 24.014 2.797 1.00 23.98 ? 138 GLY A O 1 ATOM 1090 N N . ALA A 1 139 ? 36.220 23.336 2.048 1.00 23.98 ? 139 ALA A N 1 ATOM 1091 C CA . ALA A 1 139 ? 36.000 24.472 1.163 1.00 23.23 ? 139 ALA A CA 1 ATOM 1092 C C . ALA A 1 139 ? 35.613 25.684 1.971 1.00 23.17 ? 139 ALA A C 1 ATOM 1093 O O . ALA A 1 139 ? 34.936 25.550 2.991 1.00 23.68 ? 139 ALA A O 1 ATOM 1094 C CB . ALA A 1 139 ? 34.913 24.152 0.154 1.00 23.27 ? 139 ALA A CB 1 ATOM 1095 N N . PRO A 1 140 ? 36.045 26.879 1.528 1.00 23.29 ? 140 PRO A N 1 ATOM 1096 C CA . PRO A 1 140 ? 35.685 28.102 2.241 1.00 23.64 ? 140 PRO A CA 1 ATOM 1097 C C . PRO A 1 140 ? 34.184 28.383 2.152 1.00 24.15 ? 140 PRO A C 1 ATOM 1098 O O . PRO A 1 140 ? 33.586 28.131 1.115 1.00 25.15 ? 140 PRO A O 1 ATOM 1099 C CB . PRO A 1 140 ? 36.486 29.180 1.513 1.00 22.72 ? 140 PRO A CB 1 ATOM 1100 C CG . PRO A 1 140 ? 36.861 28.591 0.221 1.00 22.22 ? 140 PRO A CG 1 ATOM 1101 C CD . PRO A 1 140 ? 36.999 27.144 0.438 1.00 22.55 ? 140 PRO A CD 1 ATOM 1102 N N . SER A 1 141 ? 33.599 28.904 3.230 1.00 23.86 ? 141 SER A N 1 ATOM 1103 C CA . SER A 1 141 ? 32.155 29.127 3.331 1.00 23.48 ? 141 SER A CA 1 ATOM 1104 C C . SER A 1 141 ? 31.587 30.140 2.352 1.00 23.94 ? 141 SER A C 1 ATOM 1105 O O . SER A 1 141 ? 30.379 30.126 2.078 1.00 23.53 ? 141 SER A O 1 ATOM 1106 C CB . SER A 1 141 ? 31.798 29.584 4.736 1.00 23.10 ? 141 SER A CB 1 ATOM 1107 O OG . SER A 1 141 ? 32.282 28.662 5.675 1.00 23.10 ? 141 SER A OG 1 ATOM 1108 N N . TRP A 1 142 ? 32.441 31.034 1.848 1.00 23.99 ? 142 TRP A N 1 ATOM 1109 C CA . TRP A 1 142 ? 31.982 32.085 0.950 1.00 23.56 ? 142 TRP A CA 1 ATOM 1110 C C . TRP A 1 142 ? 31.475 31.507 -0.346 1.00 24.07 ? 142 TRP A C 1 ATOM 1111 O O . TRP A 1 142 ? 30.648 32.124 -1.018 1.00 24.74 ? 142 TRP A O 1 ATOM 1112 C CB . TRP A 1 142 ? 33.052 33.145 0.740 1.00 23.47 ? 142 TRP A CB 1 ATOM 1113 C CG . TRP A 1 142 ? 34.267 32.656 0.016 1.00 24.71 ? 142 TRP A CG 1 ATOM 1114 C CD1 . TRP A 1 142 ? 35.501 32.310 0.561 1.00 25.24 ? 142 TRP A CD1 1 ATOM 1115 C CD2 . TRP A 1 142 ? 34.414 32.434 -1.430 1.00 25.86 ? 142 TRP A CD2 1 ATOM 1116 N NE1 . TRP A 1 142 ? 36.381 31.912 -0.417 1.00 25.39 ? 142 TRP A NE1 1 ATOM 1117 C CE2 . TRP A 1 142 ? 35.792 31.950 -1.633 1.00 26.13 ? 142 TRP A CE2 1 ATOM 1118 C CE3 . TRP A 1 142 ? 33.579 32.584 -2.534 1.00 25.30 ? 142 TRP A CE3 1 ATOM 1119 C CZ2 . TRP A 1 142 ? 36.280 31.632 -2.888 1.00 26.20 ? 142 TRP A CZ2 1 ATOM 1120 C CZ3 . TRP A 1 142 ? 34.081 32.258 -3.793 1.00 26.17 ? 142 TRP A CZ3 1 ATOM 1121 C CH2 . TRP A 1 142 ? 35.402 31.798 -3.966 1.00 26.75 ? 142 TRP A CH2 1 ATOM 1122 N N . LEU A 1 143 ? 31.940 30.304 -0.684 1.00 23.32 ? 143 LEU A N 1 ATOM 1123 C CA . LEU A 1 143 ? 31.470 29.581 -1.856 1.00 24.13 ? 143 LEU A CA 1 ATOM 1124 C C . LEU A 1 143 ? 29.973 29.232 -1.828 1.00 25.77 ? 143 LEU A C 1 ATOM 1125 O O . LEU A 1 143 ? 29.397 28.844 -2.866 1.00 25.70 ? 143 LEU A O 1 ATOM 1126 C CB . LEU A 1 143 ? 32.312 28.319 -2.074 1.00 23.98 ? 143 LEU A CB 1 ATOM 1127 C CG . LEU A 1 143 ? 33.676 28.554 -2.746 1.00 23.82 ? 143 LEU A CG 1 ATOM 1128 C CD1 . LEU A 1 143 ? 34.618 27.402 -2.479 1.00 22.69 ? 143 LEU A CD1 1 ATOM 1129 C CD2 . LEU A 1 143 ? 33.530 28.807 -4.249 1.00 23.29 ? 143 LEU A CD2 1 ATOM 1130 N N . ASP A 1 144 ? 29.340 29.371 -0.661 1.00 25.35 ? 144 ASP A N 1 ATOM 1131 C CA . ASP A 1 144 ? 27.918 29.107 -0.549 1.00 25.53 ? 144 ASP A CA 1 ATOM 1132 C C . ASP A 1 144 ? 27.064 30.058 -1.397 1.00 25.24 ? 144 ASP A C 1 ATOM 1133 O O . ASP A 1 144 ? 25.992 29.664 -1.851 1.00 25.75 ? 144 ASP A O 1 ATOM 1134 C CB . ASP A 1 144 ? 27.451 29.160 0.904 1.00 28.71 ? 144 ASP A CB 1 ATOM 1135 C CG . ASP A 1 144 ? 27.933 27.970 1.747 1.00 32.09 ? 144 ASP A CG 1 ATOM 1136 O OD1 . ASP A 1 144 ? 28.274 26.885 1.194 1.00 33.80 ? 144 ASP A OD1 1 ATOM 1137 O OD2 . ASP A 1 144 ? 27.944 28.131 2.996 1.00 33.60 ? 144 ASP A OD2 1 ATOM 1138 N N . LEU A 1 145 ? 27.510 31.300 -1.602 1.00 24.17 ? 145 LEU A N 1 ATOM 1139 C CA . LEU A 1 145 ? 26.799 32.202 -2.513 1.00 24.15 ? 145 LEU A CA 1 ATOM 1140 C C . LEU A 1 145 ? 26.907 31.738 -3.974 1.00 23.80 ? 145 LEU A C 1 ATOM 1141 O O . LEU A 1 145 ? 25.882 31.468 -4.602 1.00 23.79 ? 145 LEU A O 1 ATOM 1142 C CB . LEU A 1 145 ? 27.198 33.682 -2.349 1.00 24.72 ? 145 LEU A CB 1 ATOM 1143 C CG . LEU A 1 145 ? 26.244 34.699 -3.019 1.00 25.23 ? 145 LEU A CG 1 ATOM 1144 C CD1 . LEU A 1 145 ? 24.723 34.336 -2.897 1.00 24.19 ? 145 LEU A CD1 1 ATOM 1145 C CD2 . LEU A 1 145 ? 26.494 36.119 -2.512 1.00 25.04 ? 145 LEU A CD2 1 ATOM 1146 N N . PRO A 1 146 ? 28.137 31.618 -4.515 1.00 23.52 ? 146 PRO A N 1 ATOM 1147 C CA . PRO A 1 146 ? 28.262 31.002 -5.835 1.00 22.73 ? 146 PRO A CA 1 ATOM 1148 C C . PRO A 1 146 ? 27.409 29.737 -5.996 1.00 22.13 ? 146 PRO A C 1 ATOM 1149 O O . PRO A 1 146 ? 26.653 29.646 -6.976 1.00 22.14 ? 146 PRO A O 1 ATOM 1150 C CB . PRO A 1 146 ? 29.751 30.665 -5.937 1.00 22.54 ? 146 PRO A CB 1 ATOM 1151 C CG . PRO A 1 146 ? 30.430 31.580 -5.012 1.00 23.56 ? 146 PRO A CG 1 ATOM 1152 C CD . PRO A 1 146 ? 29.428 32.143 -4.036 1.00 23.95 ? 146 PRO A CD 1 ATOM 1153 N N . ILE A 1 147 ? 27.517 28.792 -5.055 1.00 21.17 ? 147 ILE A N 1 ATOM 1154 C CA . ILE A 1 147 ? 26.787 27.511 -5.152 1.00 21.35 ? 147 ILE A CA 1 ATOM 1155 C C . ILE A 1 147 ? 25.274 27.722 -5.212 1.00 21.76 ? 147 ILE A C 1 ATOM 1156 O O . ILE A 1 147 ? 24.587 27.137 -6.056 1.00 21.37 ? 147 ILE A O 1 ATOM 1157 C CB . ILE A 1 147 ? 27.171 26.497 -4.021 1.00 21.06 ? 147 ILE A CB 1 ATOM 1158 C CG1 . ILE A 1 147 ? 28.608 25.983 -4.186 1.00 21.22 ? 147 ILE A CG1 1 ATOM 1159 C CG2 . ILE A 1 147 ? 26.239 25.310 -3.991 1.00 20.34 ? 147 ILE A CG2 1 ATOM 1160 C CD1 . ILE A 1 147 ? 29.019 25.622 -5.614 1.00 21.01 ? 147 ILE A CD1 1 ATOM 1161 N N . LYS A 1 148 ? 24.759 28.578 -4.340 1.00 23.14 ? 148 LYS A N 1 ATOM 1162 C CA . LYS A 1 148 ? 23.343 28.880 -4.349 1.00 24.80 ? 148 LYS A CA 1 ATOM 1163 C C . LYS A 1 148 ? 22.925 29.457 -5.711 1.00 25.67 ? 148 LYS A C 1 ATOM 1164 O O . LYS A 1 148 ? 21.856 29.113 -6.239 1.00 26.03 ? 148 LYS A O 1 ATOM 1165 C CB . LYS A 1 148 ? 22.976 29.833 -3.217 1.00 26.50 ? 148 LYS A CB 1 ATOM 1166 C CG . LYS A 1 148 ? 21.483 29.951 -3.028 1.00 30.25 ? 148 LYS A CG 1 ATOM 1167 C CD . LYS A 1 148 ? 21.069 31.213 -2.310 1.00 32.93 ? 148 LYS A CD 1 ATOM 1168 C CE . LYS A 1 148 ? 20.778 30.958 -0.844 1.00 34.88 ? 148 LYS A CE 1 ATOM 1169 N NZ . LYS A 1 148 ? 19.944 32.081 -0.276 1.00 38.47 ? 148 LYS A NZ 1 ATOM 1170 N N . VAL A 1 149 ? 23.775 30.306 -6.290 1.00 24.65 ? 149 VAL A N 1 ATOM 1171 C CA . VAL A 1 149 ? 23.454 30.956 -7.555 1.00 23.86 ? 149 VAL A CA 1 ATOM 1172 C C . VAL A 1 149 ? 23.466 29.962 -8.712 1.00 24.86 ? 149 VAL A C 1 ATOM 1173 O O . VAL A 1 149 ? 22.550 29.953 -9.542 1.00 25.81 ? 149 VAL A O 1 ATOM 1174 C CB . VAL A 1 149 ? 24.394 32.126 -7.836 1.00 23.33 ? 149 VAL A CB 1 ATOM 1175 C CG1 . VAL A 1 149 ? 24.152 32.684 -9.213 1.00 23.32 ? 149 VAL A CG1 1 ATOM 1176 C CG2 . VAL A 1 149 ? 24.203 33.221 -6.786 1.00 23.28 ? 149 VAL A CG2 1 ATOM 1177 N N . LEU A 1 150 ? 24.491 29.112 -8.762 1.00 24.97 ? 150 LEU A N 1 ATOM 1178 C CA . LEU A 1 150 ? 24.593 28.117 -9.831 1.00 24.02 ? 150 LEU A CA 1 ATOM 1179 C C . LEU A 1 150 ? 23.459 27.116 -9.746 1.00 24.41 ? 150 LEU A C 1 ATOM 1180 O O . LEU A 1 150 ? 22.979 26.640 -10.773 1.00 25.90 ? 150 LEU A O 1 ATOM 1181 C CB . LEU A 1 150 ? 25.938 27.395 -9.798 1.00 24.37 ? 150 LEU A CB 1 ATOM 1182 C CG . LEU A 1 150 ? 27.202 28.203 -10.134 1.00 25.03 ? 150 LEU A CG 1 ATOM 1183 C CD1 . LEU A 1 150 ? 28.462 27.512 -9.612 1.00 24.35 ? 150 LEU A CD1 1 ATOM 1184 C CD2 . LEU A 1 150 ? 27.328 28.533 -11.631 1.00 23.44 ? 150 LEU A CD2 1 ATOM 1185 N N . ASN A 1 151 ? 23.029 26.795 -8.526 1.00 24.01 ? 151 ASN A N 1 ATOM 1186 C CA . ASN A 1 151 ? 21.902 25.875 -8.320 1.00 22.79 ? 151 ASN A CA 1 ATOM 1187 C C . ASN A 1 151 ? 20.528 26.458 -8.642 1.00 21.72 ? 151 ASN A C 1 ATOM 1188 O O . ASN A 1 151 ? 19.550 25.738 -8.655 1.00 21.13 ? 151 ASN A O 1 ATOM 1189 C CB . ASN A 1 151 ? 21.909 25.307 -6.895 1.00 22.68 ? 151 ASN A CB 1 ATOM 1190 C CG . ASN A 1 151 ? 22.957 24.231 -6.697 1.00 22.70 ? 151 ASN A CG 1 ATOM 1191 O OD1 . ASN A 1 151 ? 23.310 23.499 -7.620 1.00 23.83 ? 151 ASN A OD1 1 ATOM 1192 N ND2 . ASN A 1 151 ? 23.458 24.131 -5.488 1.00 22.56 ? 151 ASN A ND2 1 ATOM 1193 N N . ALA A 1 152 ? 20.454 27.761 -8.886 1.00 22.20 ? 152 ALA A N 1 ATOM 1194 C CA . ALA A 1 152 ? 19.197 28.386 -9.297 1.00 22.35 ? 152 ALA A CA 1 ATOM 1195 C C . ALA A 1 152 ? 18.889 28.045 -10.754 1.00 23.32 ? 152 ALA A C 1 ATOM 1196 O O . ALA A 1 152 ? 17.731 27.923 -11.143 1.00 23.19 ? 152 ALA A O 1 ATOM 1197 C CB . ALA A 1 152 ? 19.273 29.867 -9.111 1.00 21.74 ? 152 ALA A CB 1 ATOM 1198 N N . ASP A 1 153 ? 19.953 27.872 -11.538 1.00 24.86 ? 153 ASP A N 1 ATOM 1199 C CA . ASP A 1 153 ? 19.901 27.597 -12.973 1.00 24.81 ? 153 ASP A CA 1 ATOM 1200 C C . ASP A 1 153 ? 19.479 26.150 -13.233 1.00 25.68 ? 153 ASP A C 1 ATOM 1201 O O . ASP A 1 153 ? 20.315 25.246 -13.257 1.00 26.05 ? 153 ASP A O 1 ATOM 1202 C CB . ASP A 1 153 ? 21.280 27.892 -13.567 1.00 24.46 ? 153 ASP A CB 1 ATOM 1203 C CG . ASP A 1 153 ? 21.341 27.705 -15.064 1.00 25.24 ? 153 ASP A CG 1 ATOM 1204 O OD1 . ASP A 1 153 ? 20.356 27.223 -15.649 1.00 25.97 ? 153 ASP A OD1 1 ATOM 1205 O OD2 . ASP A 1 153 ? 22.395 28.035 -15.662 1.00 25.48 ? 153 ASP A OD2 1 ATOM 1206 N N . GLN A 1 154 ? 18.177 25.939 -13.429 1.00 26.50 ? 154 GLN A N 1 ATOM 1207 C CA . GLN A 1 154 ? 17.631 24.593 -13.577 1.00 26.68 ? 154 GLN A CA 1 ATOM 1208 C C . GLN A 1 154 ? 18.057 23.991 -14.898 1.00 26.00 ? 154 GLN A C 1 ATOM 1209 O O . GLN A 1 154 ? 18.325 22.794 -14.965 1.00 26.26 ? 154 GLN A O 1 ATOM 1210 C CB . GLN A 1 154 ? 16.106 24.585 -13.488 1.00 28.14 ? 154 GLN A CB 1 ATOM 1211 C CG . GLN A 1 154 ? 15.484 24.985 -12.147 1.00 29.82 ? 154 GLN A CG 1 ATOM 1212 C CD . GLN A 1 154 ? 14.078 25.572 -12.364 1.00 33.82 ? 154 GLN A CD 1 ATOM 1213 O OE1 . GLN A 1 154 ? 13.122 24.841 -12.676 1.00 33.76 ? 154 GLN A OE1 1 ATOM 1214 N NE2 . GLN A 1 154 ? 13.961 26.911 -12.252 1.00 34.61 ? 154 GLN A NE2 1 ATOM 1215 N N . GLY A 1 155 ? 18.105 24.831 -15.936 1.00 25.91 ? 155 GLY A N 1 ATOM 1216 C CA . GLY A 1 155 ? 18.569 24.463 -17.276 1.00 23.90 ? 155 GLY A CA 1 ATOM 1217 C C . GLY A 1 155 ? 19.937 23.823 -17.235 1.00 24.45 ? 155 GLY A C 1 ATOM 1218 O O . GLY A 1 155 ? 20.094 22.687 -17.668 1.00 25.54 ? 155 GLY A O 1 ATOM 1219 N N . THR A 1 156 ? 20.924 24.524 -16.680 1.00 24.09 ? 156 THR A N 1 ATOM 1220 C CA . THR A 1 156 ? 22.266 23.956 -16.566 1.00 23.93 ? 156 THR A CA 1 ATOM 1221 C C . THR A 1 156 ? 22.266 22.649 -15.779 1.00 24.58 ? 156 THR A C 1 ATOM 1222 O O . THR A 1 156 ? 22.911 21.683 -16.186 1.00 27.00 ? 156 THR A O 1 ATOM 1223 C CB . THR A 1 156 ? 23.306 24.951 -15.998 1.00 23.54 ? 156 THR A CB 1 ATOM 1224 O OG1 . THR A 1 156 ? 23.560 25.990 -16.963 1.00 23.79 ? 156 THR A OG1 1 ATOM 1225 C CG2 . THR A 1 156 ? 24.631 24.244 -15.679 1.00 22.74 ? 156 THR A CG2 1 ATOM 1226 N N . SER A 1 157 ? 21.546 22.607 -14.668 1.00 23.62 ? 157 SER A N 1 ATOM 1227 C CA . SER A 1 157 ? 21.504 21.398 -13.854 1.00 23.31 ? 157 SER A CA 1 ATOM 1228 C C . SER A 1 157 ? 21.079 20.193 -14.676 1.00 23.09 ? 157 SER A C 1 ATOM 1229 O O . SER A 1 157 ? 21.756 19.169 -14.691 1.00 24.40 ? 157 SER A O 1 ATOM 1230 C CB . SER A 1 157 ? 20.551 21.575 -12.671 1.00 23.71 ? 157 SER A CB 1 ATOM 1231 O OG . SER A 1 157 ? 20.555 20.428 -11.846 1.00 23.52 ? 157 SER A OG 1 ATOM 1232 N N . ALA A 1 158 ? 19.963 20.328 -15.377 1.00 22.75 ? 158 ALA A N 1 ATOM 1233 C CA . ALA A 1 158 ? 19.379 19.208 -16.101 1.00 21.90 ? 158 ALA A CA 1 ATOM 1234 C C . ALA A 1 158 ? 20.314 18.730 -17.187 1.00 21.30 ? 158 ALA A C 1 ATOM 1235 O O . ALA A 1 158 ? 20.450 17.537 -17.380 1.00 22.60 ? 158 ALA A O 1 ATOM 1236 C CB . ALA A 1 158 ? 18.001 19.570 -16.671 1.00 20.55 ? 158 ALA A CB 1 ATOM 1237 N N . THR A 1 159 ? 20.979 19.659 -17.864 1.00 20.85 ? 159 THR A N 1 ATOM 1238 C CA . THR A 1 159 ? 21.954 19.318 -18.907 1.00 20.79 ? 159 THR A CA 1 ATOM 1239 C C . THR A 1 159 ? 23.158 18.569 -18.337 1.00 21.43 ? 159 THR A C 1 ATOM 1240 O O . THR A 1 159 ? 23.535 17.524 -18.853 1.00 23.18 ? 159 THR A O 1 ATOM 1241 C CB . THR A 1 159 ? 22.495 20.571 -19.652 1.00 20.14 ? 159 THR A CB 1 ATOM 1242 O OG1 . THR A 1 159 ? 21.450 21.533 -19.850 1.00 20.02 ? 159 THR A OG1 1 ATOM 1243 C CG2 . THR A 1 159 ? 23.125 20.182 -20.989 1.00 19.33 ? 159 THR A CG2 1 ATOM 1244 N N . VAL A 1 160 ? 23.776 19.108 -17.295 1.00 21.52 ? 160 VAL A N 1 ATOM 1245 C CA . VAL A 1 160 ? 24.900 18.433 -16.664 1.00 23.20 ? 160 VAL A CA 1 ATOM 1246 C C . VAL A 1 160 ? 24.531 17.008 -16.204 1.00 24.70 ? 160 VAL A C 1 ATOM 1247 O O . VAL A 1 160 ? 25.319 16.077 -16.375 1.00 24.96 ? 160 VAL A O 1 ATOM 1248 C CB . VAL A 1 160 ? 25.482 19.271 -15.517 1.00 23.08 ? 160 VAL A CB 1 ATOM 1249 C CG1 . VAL A 1 160 ? 26.485 18.476 -14.699 1.00 22.18 ? 160 VAL A CG1 1 ATOM 1250 C CG2 . VAL A 1 160 ? 26.131 20.506 -16.081 1.00 23.16 ? 160 VAL A CG2 1 ATOM 1251 N N . GLN A 1 161 ? 23.331 16.830 -15.655 1.00 26.19 ? 161 GLN A N 1 ATOM 1252 C CA . GLN A 1 161 ? 22.860 15.486 -15.309 1.00 28.04 ? 161 GLN A CA 1 ATOM 1253 C C . GLN A 1 161 ? 22.782 14.553 -16.519 1.00 29.82 ? 161 GLN A C 1 ATOM 1254 O O . GLN A 1 161 ? 23.109 13.365 -16.405 1.00 30.56 ? 161 GLN A O 1 ATOM 1255 C CB . GLN A 1 161 ? 21.501 15.529 -14.647 1.00 27.44 ? 161 GLN A CB 1 ATOM 1256 C CG . GLN A 1 161 ? 21.482 16.106 -13.269 1.00 26.59 ? 161 GLN A CG 1 ATOM 1257 C CD . GLN A 1 161 ? 20.079 16.097 -12.722 1.00 26.16 ? 161 GLN A CD 1 ATOM 1258 O OE1 . GLN A 1 161 ? 19.403 15.068 -12.757 1.00 25.41 ? 161 GLN A OE1 1 ATOM 1259 N NE2 . GLN A 1 161 ? 19.623 17.239 -12.231 1.00 25.58 ? 161 GLN A NE2 1 ATOM 1260 N N . MET A 1 162 ? 22.343 15.085 -17.660 1.00 30.09 ? 162 MET A N 1 ATOM 1261 C CA . MET A 1 162 ? 22.312 14.321 -18.896 1.00 31.78 ? 162 MET A CA 1 ATOM 1262 C C . MET A 1 162 ? 23.721 13.945 -19.332 1.00 31.43 ? 162 MET A C 1 ATOM 1263 O O . MET A 1 162 ? 23.964 12.804 -19.703 1.00 31.72 ? 162 MET A O 1 ATOM 1264 C CB . MET A 1 162 ? 21.610 15.101 -19.999 1.00 35.97 ? 162 MET A CB 1 ATOM 1265 C CG . MET A 1 162 ? 21.112 14.251 -21.164 1.00 41.04 ? 162 MET A CG 1 ATOM 1266 S SD . MET A 1 162 ? 20.802 15.255 -22.640 1.00 52.33 ? 162 MET A SD 1 ATOM 1267 C CE . MET A 1 162 ? 22.449 15.915 -23.011 1.00 46.30 ? 162 MET A CE 1 ATOM 1268 N N . LEU A 1 163 ? 24.645 14.903 -19.272 1.00 31.24 ? 163 LEU A N 1 ATOM 1269 C CA . LEU A 1 163 ? 26.032 14.685 -19.687 1.00 30.73 ? 163 LEU A CA 1 ATOM 1270 C C . LEU A 1 163 ? 26.719 13.607 -18.878 1.00 30.26 ? 163 LEU A C 1 ATOM 1271 O O . LEU A 1 163 ? 27.384 12.729 -19.426 1.00 29.98 ? 163 LEU A O 1 ATOM 1272 C CB . LEU A 1 163 ? 26.840 15.970 -19.541 1.00 32.22 ? 163 LEU A CB 1 ATOM 1273 C CG . LEU A 1 163 ? 26.664 17.028 -20.623 1.00 33.25 ? 163 LEU A CG 1 ATOM 1274 C CD1 . LEU A 1 163 ? 27.564 18.219 -20.316 1.00 33.54 ? 163 LEU A CD1 1 ATOM 1275 C CD2 . LEU A 1 163 ? 26.979 16.446 -21.998 1.00 32.77 ? 163 LEU A CD2 1 ATOM 1276 N N . LEU A 1 164 ? 26.560 13.691 -17.566 1.00 29.37 ? 164 LEU A N 1 ATOM 1277 C CA . LEU A 1 164 ? 27.234 12.790 -16.659 1.00 28.14 ? 164 LEU A CA 1 ATOM 1278 C C . LEU A 1 164 ? 26.557 11.420 -16.624 1.00 28.52 ? 164 LEU A C 1 ATOM 1279 O O . LEU A 1 164 ? 27.239 10.400 -16.636 1.00 29.68 ? 164 LEU A O 1 ATOM 1280 C CB . LEU A 1 164 ? 27.323 13.412 -15.256 1.00 26.96 ? 164 LEU A CB 1 ATOM 1281 C CG . LEU A 1 164 ? 28.005 14.775 -15.046 1.00 25.81 ? 164 LEU A CG 1 ATOM 1282 C CD1 . LEU A 1 164 ? 28.025 15.105 -13.584 1.00 26.04 ? 164 LEU A CD1 1 ATOM 1283 C CD2 . LEU A 1 164 ? 29.419 14.822 -15.567 1.00 26.57 ? 164 LEU A CD2 1 ATOM 1284 N N . ASN A 1 165 ? 25.228 11.386 -16.588 1.00 28.36 ? 165 ASN A N 1 ATOM 1285 C CA . ASN A 1 165 ? 24.528 10.109 -16.450 1.00 29.25 ? 165 ASN A CA 1 ATOM 1286 C C . ASN A 1 165 ? 24.504 9.305 -17.748 1.00 29.97 ? 165 ASN A C 1 ATOM 1287 O O . ASN A 1 165 ? 24.577 8.084 -17.707 1.00 30.50 ? 165 ASN A O 1 ATOM 1288 C CB . ASN A 1 165 ? 23.081 10.278 -15.950 1.00 29.70 ? 165 ASN A CB 1 ATOM 1289 C CG . ASN A 1 165 ? 22.980 10.779 -14.513 1.00 28.98 ? 165 ASN A CG 1 ATOM 1290 O OD1 . ASN A 1 165 ? 23.959 11.188 -13.898 1.00 29.41 ? 165 ASN A OD1 1 ATOM 1291 N ND2 . ASN A 1 165 ? 21.768 10.749 -13.981 1.00 29.32 ? 165 ASN A ND2 1 ATOM 1292 N N . ASP A 1 166 ? 24.386 9.980 -18.891 1.00 30.34 ? 166 ASP A N 1 ATOM 1293 C CA . ASP A 1 166 ? 24.164 9.282 -20.159 1.00 30.07 ? 166 ASP A CA 1 ATOM 1294 C C . ASP A 1 166 ? 25.208 9.516 -21.226 1.00 29.55 ? 166 ASP A C 1 ATOM 1295 O O . ASP A 1 166 ? 25.742 8.554 -21.771 1.00 31.30 ? 166 ASP A O 1 ATOM 1296 C CB . ASP A 1 166 ? 22.796 9.607 -20.737 1.00 31.44 ? 166 ASP A CB 1 ATOM 1297 C CG . ASP A 1 166 ? 21.693 9.421 -19.742 1.00 34.48 ? 166 ASP A CG 1 ATOM 1298 O OD1 . ASP A 1 166 ? 21.756 8.469 -18.931 1.00 35.38 ? 166 ASP A OD1 1 ATOM 1299 O OD2 . ASP A 1 166 ? 20.752 10.240 -19.775 1.00 37.51 ? 166 ASP A OD2 1 ATOM 1300 N N . THR A 1 167 ? 25.482 10.775 -21.553 1.00 28.46 ? 167 THR A N 1 ATOM 1301 C CA . THR A 1 167 ? 26.388 11.067 -22.657 1.00 29.48 ? 167 THR A CA 1 ATOM 1302 C C . THR A 1 167 ? 27.789 10.477 -22.452 1.00 30.95 ? 167 THR A C 1 ATOM 1303 O O . THR A 1 167 ? 28.291 9.776 -23.331 1.00 32.05 ? 167 THR A O 1 ATOM 1304 C CB . THR A 1 167 ? 26.444 12.554 -23.001 1.00 29.01 ? 167 THR A CB 1 ATOM 1305 O OG1 . THR A 1 167 ? 25.108 13.057 -23.097 1.00 30.35 ? 167 THR A OG1 1 ATOM 1306 C CG2 . THR A 1 167 ? 27.129 12.751 -24.339 1.00 27.21 ? 167 THR A CG2 1 ATOM 1307 N N . CYS A 1 168 ? 28.399 10.730 -21.294 1.00 32.09 ? 168 CYS A N 1 ATOM 1308 C CA . CYS A 1 168 ? 29.734 10.196 -21.003 1.00 32.65 ? 168 CYS A CA 1 ATOM 1309 C C . CYS A 1 168 ? 29.805 8.679 -21.208 1.00 31.86 ? 168 CYS A C 1 ATOM 1310 O O . CYS A 1 168 ? 30.479 8.240 -22.132 1.00 33.59 ? 168 CYS A O 1 ATOM 1311 C CB . CYS A 1 168 ? 30.230 10.590 -19.605 1.00 34.61 ? 168 CYS A CB 1 ATOM 1312 S SG . CYS A 1 168 ? 32.026 10.461 -19.375 1.00 36.63 ? 168 CYS A SG 1 ATOM 1313 N N . PRO A 1 169 ? 29.108 7.876 -20.373 1.00 30.80 ? 169 PRO A N 1 ATOM 1314 C CA . PRO A 1 169 ? 29.283 6.436 -20.540 1.00 30.92 ? 169 PRO A CA 1 ATOM 1315 C C . PRO A 1 169 ? 29.048 5.995 -21.985 1.00 31.02 ? 169 PRO A C 1 ATOM 1316 O O . PRO A 1 169 ? 29.894 5.305 -22.552 1.00 32.06 ? 169 PRO A O 1 ATOM 1317 C CB . PRO A 1 169 ? 28.228 5.827 -19.610 1.00 30.18 ? 169 PRO A CB 1 ATOM 1318 C CG . PRO A 1 169 ? 27.898 6.855 -18.654 1.00 30.74 ? 169 PRO A CG 1 ATOM 1319 C CD . PRO A 1 169 ? 28.104 8.182 -19.340 1.00 31.41 ? 169 PRO A CD 1 ATOM 1320 N N . LEU A 1 170 ? 27.940 6.421 -22.581 1.00 30.33 ? 170 LEU A N 1 ATOM 1321 C CA . LEU A 1 170 ? 27.622 6.057 -23.960 1.00 32.02 ? 170 LEU A CA 1 ATOM 1322 C C . LEU A 1 170 ? 28.803 6.330 -24.901 1.00 31.95 ? 170 LEU A C 1 ATOM 1323 O O . LEU A 1 170 ? 29.235 5.459 -25.670 1.00 32.55 ? 170 LEU A O 1 ATOM 1324 C CB . LEU A 1 170 ? 26.378 6.820 -24.444 1.00 32.91 ? 170 LEU A CB 1 ATOM 1325 C CG . LEU A 1 170 ? 26.076 6.635 -25.936 1.00 35.65 ? 170 LEU A CG 1 ATOM 1326 C CD1 . LEU A 1 170 ? 25.236 5.363 -26.166 1.00 36.46 ? 170 LEU A CD1 1 ATOM 1327 C CD2 . LEU A 1 170 ? 25.431 7.881 -26.593 1.00 35.19 ? 170 LEU A CD2 1 ATOM 1328 N N . PHE A 1 171 ? 29.321 7.547 -24.808 1.00 30.90 ? 171 PHE A N 1 ATOM 1329 C CA . PHE A 1 171 ? 30.366 8.035 -25.685 1.00 30.12 ? 171 PHE A CA 1 ATOM 1330 C C . PHE A 1 171 ? 31.665 7.298 -25.495 1.00 30.03 ? 171 PHE A C 1 ATOM 1331 O O . PHE A 1 171 ? 32.429 7.114 -26.445 1.00 31.74 ? 171 PHE A O 1 ATOM 1332 C CB . PHE A 1 171 ? 30.586 9.524 -25.431 1.00 29.78 ? 171 PHE A CB 1 ATOM 1333 C CG . PHE A 1 171 ? 31.657 10.142 -26.278 1.00 29.85 ? 171 PHE A CG 1 ATOM 1334 C CD1 . PHE A 1 171 ? 31.487 10.286 -27.651 1.00 29.72 ? 171 PHE A CD1 1 ATOM 1335 C CD2 . PHE A 1 171 ? 32.831 10.617 -25.697 1.00 29.48 ? 171 PHE A CD2 1 ATOM 1336 C CE1 . PHE A 1 171 ? 32.484 10.888 -28.433 1.00 29.80 ? 171 PHE A CE1 1 ATOM 1337 C CE2 . PHE A 1 171 ? 33.820 11.219 -26.472 1.00 29.16 ? 171 PHE A CE2 1 ATOM 1338 C CZ . PHE A 1 171 ? 33.646 11.351 -27.841 1.00 28.72 ? 171 PHE A CZ 1 ATOM 1339 N N . VAL A 1 172 ? 31.942 6.891 -24.268 1.00 29.43 ? 172 VAL A N 1 ATOM 1340 C CA . VAL A 1 172 ? 33.210 6.248 -24.009 1.00 29.78 ? 172 VAL A CA 1 ATOM 1341 C C . VAL A 1 172 ? 33.171 4.808 -24.506 1.00 31.26 ? 172 VAL A C 1 ATOM 1342 O O . VAL A 1 172 ? 34.178 4.315 -25.038 1.00 31.76 ? 172 VAL A O 1 ATOM 1343 C CB . VAL A 1 172 ? 33.611 6.347 -22.539 1.00 29.58 ? 172 VAL A CB 1 ATOM 1344 C CG1 . VAL A 1 172 ? 34.920 5.617 -22.294 1.00 29.64 ? 172 VAL A CG1 1 ATOM 1345 C CG2 . VAL A 1 172 ? 33.735 7.799 -22.146 1.00 29.02 ? 172 VAL A CG2 1 ATOM 1346 N N . ARG A 1 173 ? 32.012 4.155 -24.352 1.00 31.86 ? 173 ARG A N 1 ATOM 1347 C CA . ARG A 1 173 ? 31.795 2.831 -24.922 1.00 33.66 ? 173 ARG A CA 1 ATOM 1348 C C . ARG A 1 173 ? 32.134 2.924 -26.405 1.00 32.93 ? 173 ARG A C 1 ATOM 1349 O O . ARG A 1 173 ? 32.850 2.077 -26.939 1.00 34.51 ? 173 ARG A O 1 ATOM 1350 C CB . ARG A 1 173 ? 30.349 2.350 -24.734 1.00 37.59 ? 173 ARG A CB 1 ATOM 1351 C CG . ARG A 1 173 ? 29.908 2.038 -23.294 1.00 43.05 ? 173 ARG A CG 1 ATOM 1352 C CD . ARG A 1 173 ? 29.959 0.549 -22.928 1.00 49.66 ? 173 ARG A CD 1 ATOM 1353 N NE . ARG A 1 173 ? 31.232 0.147 -22.309 1.00 57.08 ? 173 ARG A NE 1 ATOM 1354 C CZ . ARG A 1 173 ? 31.399 -0.167 -21.017 1.00 61.43 ? 173 ARG A CZ 1 ATOM 1355 N NH1 . ARG A 1 173 ? 30.371 -0.138 -20.167 1.00 62.89 ? 173 ARG A NH1 1 ATOM 1356 N NH2 . ARG A 1 173 ? 32.606 -0.513 -20.569 1.00 58.51 ? 173 ARG A NH2 1 ATOM 1357 N N . GLY A 1 174 ? 31.650 3.982 -27.050 1.00 30.86 ? 174 GLY A N 1 ATOM 1358 C CA . GLY A 1 174 ? 31.898 4.218 -28.463 1.00 29.95 ? 174 GLY A CA 1 ATOM 1359 C C . GLY A 1 174 ? 33.359 4.438 -28.764 1.00 31.11 ? 174 GLY A C 1 ATOM 1360 O O . GLY A 1 174 ? 33.875 3.929 -29.766 1.00 31.54 ? 174 GLY A O 1 ATOM 1361 N N . LEU A 1 175 ? 34.031 5.196 -27.895 1.00 30.86 ? 175 LEU A N 1 ATOM 1362 C CA . LEU A 1 175 ? 35.461 5.447 -28.037 1.00 29.88 ? 175 LEU A CA 1 ATOM 1363 C C . LEU A 1 175 ? 36.271 4.165 -27.901 1.00 31.78 ? 175 LEU A C 1 ATOM 1364 O O . LEU A 1 175 ? 37.240 3.966 -28.648 1.00 31.38 ? 175 LEU A O 1 ATOM 1365 C CB . LEU A 1 175 ? 35.946 6.447 -26.999 1.00 28.89 ? 175 LEU A CB 1 ATOM 1366 C CG . LEU A 1 175 ? 35.794 7.944 -27.235 1.00 28.98 ? 175 LEU A CG 1 ATOM 1367 C CD1 . LEU A 1 175 ? 36.383 8.688 -26.050 1.00 27.82 ? 175 LEU A CD1 1 ATOM 1368 C CD2 . LEU A 1 175 ? 36.455 8.403 -28.551 1.00 29.03 ? 175 LEU A CD2 1 ATOM 1369 N N . LEU A 1 176 ? 35.879 3.305 -26.949 1.00 31.64 ? 176 LEU A N 1 ATOM 1370 C CA . LEU A 1 176 ? 36.615 2.055 -26.677 1.00 31.66 ? 176 LEU A CA 1 ATOM 1371 C C . LEU A 1 176 ? 36.527 1.079 -27.835 1.00 31.45 ? 176 LEU A C 1 ATOM 1372 O O . LEU A 1 176 ? 37.474 0.348 -28.096 1.00 31.99 ? 176 LEU A O 1 ATOM 1373 C CB . LEU A 1 176 ? 36.149 1.376 -25.378 1.00 31.10 ? 176 LEU A CB 1 ATOM 1374 C CG . LEU A 1 176 ? 36.457 2.056 -24.035 1.00 31.64 ? 176 LEU A CG 1 ATOM 1375 C CD1 . LEU A 1 176 ? 35.753 1.349 -22.895 1.00 31.09 ? 176 LEU A CD1 1 ATOM 1376 C CD2 . LEU A 1 176 ? 37.957 2.169 -23.740 1.00 30.52 ? 176 LEU A CD2 1 ATOM 1377 N N . GLU A 1 177 ? 35.386 1.062 -28.518 1.00 32.63 ? 177 GLU A N 1 ATOM 1378 C CA . GLU A 1 177 ? 35.241 0.244 -29.716 1.00 34.65 ? 177 GLU A CA 1 ATOM 1379 C C . GLU A 1 177 ? 36.097 0.853 -30.833 1.00 33.08 ? 177 GLU A C 1 ATOM 1380 O O . GLU A 1 177 ? 37.010 0.208 -31.335 1.00 31.08 ? 177 GLU A O 1 ATOM 1381 C CB . GLU A 1 177 ? 33.778 0.138 -30.161 1.00 38.60 ? 177 GLU A CB 1 ATOM 1382 C CG . GLU A 1 177 ? 32.820 -0.511 -29.162 1.00 43.81 ? 177 GLU A CG 1 ATOM 1383 C CD . GLU A 1 177 ? 31.332 -0.376 -29.572 1.00 50.39 ? 177 GLU A CD 1 ATOM 1384 O OE1 . GLU A 1 177 ? 30.470 -0.424 -28.654 1.00 52.78 ? 177 GLU A OE1 1 ATOM 1385 O OE2 . GLU A 1 177 ? 31.027 -0.226 -30.793 1.00 48.08 ? 177 GLU A OE2 1 ATOM 1386 N N . ALA A 1 178 ? 35.821 2.112 -31.182 1.00 32.08 ? 178 ALA A N 1 ATOM 1387 C CA . ALA A 1 178 ? 36.521 2.793 -32.277 1.00 29.97 ? 178 ALA A CA 1 ATOM 1388 C C . ALA A 1 178 ? 38.052 2.784 -32.163 1.00 28.58 ? 178 ALA A C 1 ATOM 1389 O O . ALA A 1 178 ? 38.740 2.664 -33.170 1.00 27.78 ? 178 ALA A O 1 ATOM 1390 C CB . ALA A 1 178 ? 36.005 4.216 -32.442 1.00 28.05 ? 178 ALA A CB 1 ATOM 1391 N N . GLY A 1 179 ? 38.568 2.913 -30.942 1.00 28.32 ? 179 GLY A N 1 ATOM 1392 C CA . GLY A 1 179 ? 39.993 3.123 -30.721 1.00 28.47 ? 179 GLY A CA 1 ATOM 1393 C C . GLY A 1 179 ? 40.732 1.925 -30.166 1.00 30.38 ? 179 GLY A C 1 ATOM 1394 O O . GLY A 1 179 ? 41.872 2.048 -29.740 1.00 29.37 ? 179 GLY A O 1 ATOM 1395 N N . LYS A 1 180 ? 40.073 0.770 -30.185 1.00 34.05 ? 180 LYS A N 1 ATOM 1396 C CA . LYS A 1 180 ? 40.623 -0.497 -29.695 1.00 37.47 ? 180 LYS A CA 1 ATOM 1397 C C . LYS A 1 180 ? 42.070 -0.750 -30.151 1.00 37.22 ? 180 LYS A C 1 ATOM 1398 O O . LYS A 1 180 ? 42.951 -0.997 -29.316 1.00 37.04 ? 180 LYS A O 1 ATOM 1399 C CB . LYS A 1 180 ? 39.712 -1.660 -30.119 1.00 41.15 ? 180 LYS A CB 1 ATOM 1400 C CG . LYS A 1 180 ? 39.834 -2.895 -29.246 1.00 45.47 ? 180 LYS A CG 1 ATOM 1401 C CD . LYS A 1 180 ? 39.469 -4.175 -29.994 1.00 47.68 ? 180 LYS A CD 1 ATOM 1402 C CE . LYS A 1 180 ? 39.442 -5.353 -29.021 1.00 50.76 ? 180 LYS A CE 1 ATOM 1403 N NZ . LYS A 1 180 ? 39.448 -6.666 -29.719 1.00 54.47 ? 180 LYS A NZ 1 ATOM 1404 N N . SER A 1 181 ? 42.306 -0.675 -31.463 1.00 36.34 ? 181 SER A N 1 ATOM 1405 C CA . SER A 1 181 ? 43.646 -0.871 -32.035 1.00 36.87 ? 181 SER A CA 1 ATOM 1406 C C . SER A 1 181 ? 44.703 -0.030 -31.314 1.00 35.84 ? 181 SER A C 1 ATOM 1407 O O . SER A 1 181 ? 45.707 -0.564 -30.872 1.00 36.03 ? 181 SER A O 1 ATOM 1408 C CB . SER A 1 181 ? 43.663 -0.597 -33.554 1.00 35.39 ? 181 SER A CB 1 ATOM 1409 N N . ASP A 1 182 ? 44.462 1.273 -31.183 1.00 37.54 ? 182 ASP A N 1 ATOM 1410 C CA . ASP A 1 182 ? 45.395 2.177 -30.497 1.00 38.18 ? 182 ASP A CA 1 ATOM 1411 C C . ASP A 1 182 ? 45.531 1.878 -28.995 1.00 37.88 ? 182 ASP A C 1 ATOM 1412 O O . ASP A 1 182 ? 46.640 1.932 -28.442 1.00 36.13 ? 182 ASP A O 1 ATOM 1413 C CB . ASP A 1 182 ? 44.997 3.644 -30.713 1.00 41.20 ? 182 ASP A CB 1 ATOM 1414 C CG . ASP A 1 182 ? 45.500 4.213 -32.046 1.00 45.79 ? 182 ASP A CG 1 ATOM 1415 O OD1 . ASP A 1 182 ? 45.950 3.430 -32.909 1.00 50.81 ? 182 ASP A OD1 1 ATOM 1416 O OD2 . ASP A 1 182 ? 45.452 5.452 -32.236 1.00 45.57 ? 182 ASP A OD2 1 ATOM 1417 N N . LEU A 1 183 ? 44.411 1.547 -28.347 1.00 35.55 ? 183 LEU A N 1 ATOM 1418 C CA . LEU A 1 183 ? 44.381 1.303 -26.906 1.00 33.99 ? 183 LEU A CA 1 ATOM 1419 C C . LEU A 1 183 ? 45.146 0.056 -26.524 1.00 35.37 ? 183 LEU A C 1 ATOM 1420 O O . LEU A 1 183 ? 45.779 0.001 -25.476 1.00 35.99 ? 183 LEU A O 1 ATOM 1421 C CB . LEU A 1 183 ? 42.944 1.171 -26.414 1.00 32.72 ? 183 LEU A CB 1 ATOM 1422 C CG . LEU A 1 183 ? 42.061 2.417 -26.413 1.00 31.00 ? 183 LEU A CG 1 ATOM 1423 C CD1 . LEU A 1 183 ? 40.601 2.020 -26.487 1.00 31.21 ? 183 LEU A CD1 1 ATOM 1424 C CD2 . LEU A 1 183 ? 42.320 3.278 -25.213 1.00 30.41 ? 183 LEU A CD2 1 ATOM 1425 N N . GLU A 1 184 ? 45.086 -0.946 -27.390 1.00 38.27 ? 184 GLU A N 1 ATOM 1426 C CA . GLU A 1 184 ? 45.679 -2.241 -27.109 1.00 38.54 ? 184 GLU A CA 1 ATOM 1427 C C . GLU A 1 184 ? 47.084 -2.408 -27.701 1.00 37.34 ? 184 GLU A C 1 ATOM 1428 O O . GLU A 1 184 ? 47.689 -3.468 -27.571 1.00 38.03 ? 184 GLU A O 1 ATOM 1429 C CB . GLU A 1 184 ? 44.714 -3.356 -27.544 1.00 41.13 ? 184 GLU A CB 1 ATOM 1430 C CG . GLU A 1 184 ? 43.608 -3.637 -26.491 1.00 46.36 ? 184 GLU A CG 1 ATOM 1431 C CD . GLU A 1 184 ? 42.446 -4.520 -26.994 1.00 51.15 ? 184 GLU A CD 1 ATOM 1432 O OE1 . GLU A 1 184 ? 42.615 -5.305 -27.962 1.00 49.92 ? 184 GLU A OE1 1 ATOM 1433 O OE2 . GLU A 1 184 ? 41.347 -4.428 -26.397 1.00 54.67 ? 184 GLU A OE2 1 ATOM 1434 N N . LYS A 1 185 ? 47.613 -1.353 -28.315 1.00 35.84 ? 185 LYS A N 1 ATOM 1435 C CA . LYS A 1 185 ? 48.964 -1.376 -28.889 1.00 35.97 ? 185 LYS A CA 1 ATOM 1436 C C . LYS A 1 185 ? 50.035 -1.856 -27.903 1.00 35.25 ? 185 LYS A C 1 ATOM 1437 O O . LYS A 1 185 ? 49.910 -1.645 -26.692 1.00 34.60 ? 185 LYS A O 1 ATOM 1438 C CB . LYS A 1 185 ? 49.344 -0.005 -29.475 1.00 37.58 ? 185 LYS A CB 1 ATOM 1439 C CG . LYS A 1 185 ? 49.813 1.042 -28.452 1.00 38.63 ? 185 LYS A CG 1 ATOM 1440 C CD . LYS A 1 185 ? 50.131 2.393 -29.105 1.00 40.34 ? 185 LYS A CD 1 ATOM 1441 C CE . LYS A 1 185 ? 50.354 3.466 -28.041 1.00 41.65 ? 185 LYS A CE 1 ATOM 1442 N NZ . LYS A 1 185 ? 51.281 4.539 -28.479 1.00 42.48 ? 185 LYS A NZ 1 ATOM 1443 N N . GLN A 1 186 ? 51.065 -2.521 -28.439 1.00 36.36 ? 186 GLN A N 1 ATOM 1444 C CA . GLN A 1 186 ? 52.208 -3.024 -27.659 1.00 36.58 ? 186 GLN A CA 1 ATOM 1445 C C . GLN A 1 186 ? 53.496 -2.546 -28.326 1.00 39.92 ? 186 GLN A C 1 ATOM 1446 O O . GLN A 1 186 ? 53.796 -2.941 -29.464 1.00 41.07 ? 186 GLN A O 1 ATOM 1447 C CB . GLN A 1 186 ? 52.212 -4.559 -27.574 1.00 32.53 ? 186 GLN A CB 1 ATOM 1448 C CG . GLN A 1 186 ? 51.074 -5.180 -26.799 1.00 31.99 ? 186 GLN A CG 1 ATOM 1449 C CD . GLN A 1 186 ? 51.170 -4.984 -25.277 1.00 33.63 ? 186 GLN A CD 1 ATOM 1450 O OE1 . GLN A 1 186 ? 52.257 -4.892 -24.701 1.00 34.85 ? 186 GLN A OE1 1 ATOM 1451 N NE2 . GLN A 1 186 ? 50.019 -4.940 -24.623 1.00 32.92 ? 186 GLN A NE2 1 ATOM 1452 N N . GLU A 1 187 ? 54.248 -1.701 -27.622 1.00 41.01 ? 187 GLU A N 1 ATOM 1453 C CA . GLU A 1 187 ? 55.521 -1.179 -28.123 1.00 44.06 ? 187 GLU A CA 1 ATOM 1454 C C . GLU A 1 187 ? 56.652 -1.651 -27.217 1.00 42.26 ? 187 GLU A C 1 ATOM 1455 O O . GLU A 1 187 ? 56.566 -1.504 -26.005 1.00 41.11 ? 187 GLU A O 1 ATOM 1456 C CB . GLU A 1 187 ? 55.496 0.355 -28.161 1.00 50.84 ? 187 GLU A CB 1 ATOM 1457 C CG . GLU A 1 187 ? 54.574 0.968 -29.225 1.00 56.52 ? 187 GLU A CG 1 ATOM 1458 C CD . GLU A 1 187 ? 55.284 1.243 -30.548 1.00 61.52 ? 187 GLU A CD 1 ATOM 1459 O OE1 . GLU A 1 187 ? 56.478 0.887 -30.690 1.00 63.65 ? 187 GLU A OE1 1 ATOM 1460 O OE2 . GLU A 1 187 ? 54.643 1.826 -31.452 1.00 63.40 ? 187 GLU A OE2 1 ATOM 1461 N N . LYS A 1 188 ? 57.710 -2.205 -27.806 1.00 41.69 ? 188 LYS A N 1 ATOM 1462 C CA . LYS A 1 188 ? 58.784 -2.841 -27.039 1.00 39.17 ? 188 LYS A CA 1 ATOM 1463 C C . LYS A 1 188 ? 59.755 -1.825 -26.468 1.00 37.68 ? 188 LYS A C 1 ATOM 1464 O O . LYS A 1 188 ? 60.157 -0.897 -27.170 1.00 37.63 ? 188 LYS A O 1 ATOM 1465 C CB . LYS A 1 188 ? 59.536 -3.859 -27.900 1.00 41.34 ? 188 LYS A CB 1 ATOM 1466 C CG . LYS A 1 188 ? 58.723 -5.109 -28.233 1.00 43.38 ? 188 LYS A CG 1 ATOM 1467 C CD . LYS A 1 188 ? 59.475 -6.081 -29.144 1.00 44.26 ? 188 LYS A CD 1 ATOM 1468 C CE . LYS A 1 188 ? 59.368 -5.684 -30.605 1.00 46.25 ? 188 LYS A CE 1 ATOM 1469 N NZ . LYS A 1 188 ? 60.013 -6.693 -31.492 1.00 47.80 ? 188 LYS A NZ 1 ATOM 1470 N N . PRO A 1 189 ? 60.142 -1.998 -25.191 1.00 35.43 ? 189 PRO A N 1 ATOM 1471 C CA . PRO A 1 189 ? 61.129 -1.105 -24.589 1.00 34.40 ? 189 PRO A CA 1 ATOM 1472 C C . PRO A 1 189 ? 62.532 -1.412 -25.086 1.00 34.19 ? 189 PRO A C 1 ATOM 1473 O O . PRO A 1 189 ? 62.815 -2.531 -25.519 1.00 34.81 ? 189 PRO A O 1 ATOM 1474 C CB . PRO A 1 189 ? 61.040 -1.435 -23.099 1.00 33.66 ? 189 PRO A CB 1 ATOM 1475 C CG . PRO A 1 189 ? 60.625 -2.862 -23.064 1.00 33.46 ? 189 PRO A CG 1 ATOM 1476 C CD . PRO A 1 189 ? 59.754 -3.089 -24.276 1.00 34.36 ? 189 PRO A CD 1 ATOM 1477 N N . VAL A 1 190 ? 63.396 -0.407 -25.031 1.00 34.64 ? 190 VAL A N 1 ATOM 1478 C CA . VAL A 1 190 ? 64.818 -0.562 -25.319 1.00 32.26 ? 190 VAL A CA 1 ATOM 1479 C C . VAL A 1 190 ? 65.503 -0.089 -24.064 1.00 32.06 ? 190 VAL A C 1 ATOM 1480 O O . VAL A 1 190 ? 65.030 0.854 -23.426 1.00 33.61 ? 190 VAL A O 1 ATOM 1481 C CB . VAL A 1 190 ? 65.243 0.258 -26.550 1.00 31.06 ? 190 VAL A CB 1 ATOM 1482 C CG1 . VAL A 1 190 ? 66.698 0.649 -26.483 1.00 33.01 ? 190 VAL A CG1 1 ATOM 1483 C CG2 . VAL A 1 190 ? 64.981 -0.522 -27.808 1.00 30.54 ? 190 VAL A CG2 1 ATOM 1484 N N . ALA A 1 191 ? 66.583 -0.764 -23.684 1.00 31.99 ? 191 ALA A N 1 ATOM 1485 C CA . ALA A 1 191 ? 67.300 -0.415 -22.466 1.00 32.79 ? 191 ALA A CA 1 ATOM 1486 C C . ALA A 1 191 ? 68.764 -0.140 -22.743 1.00 33.77 ? 191 ALA A C 1 ATOM 1487 O O . ALA A 1 191 ? 69.299 -0.578 -23.769 1.00 35.58 ? 191 ALA A O 1 ATOM 1488 C CB . ALA A 1 191 ? 67.153 -1.518 -21.436 1.00 33.91 ? 191 ALA A CB 1 ATOM 1489 N N . TRP A 1 192 ? 69.400 0.585 -21.826 1.00 33.35 ? 192 TRP A N 1 ATOM 1490 C CA . TRP A 1 192 ? 70.822 0.906 -21.908 1.00 34.60 ? 192 TRP A CA 1 ATOM 1491 C C . TRP A 1 192 ? 71.330 1.353 -20.564 1.00 37.57 ? 192 TRP A C 1 ATOM 1492 O O . TRP A 1 192 ? 70.551 1.834 -19.731 1.00 37.36 ? 192 TRP A O 1 ATOM 1493 C CB . TRP A 1 192 ? 71.075 1.969 -22.966 1.00 33.33 ? 192 TRP A CB 1 ATOM 1494 C CG . TRP A 1 192 ? 70.549 3.348 -22.621 1.00 32.94 ? 192 TRP A CG 1 ATOM 1495 C CD1 . TRP A 1 192 ? 71.212 4.369 -21.936 1.00 32.46 ? 192 TRP A CD1 1 ATOM 1496 C CD2 . TRP A 1 192 ? 69.239 3.911 -22.960 1.00 32.68 ? 192 TRP A CD2 1 ATOM 1497 N NE1 . TRP A 1 192 ? 70.423 5.480 -21.823 1.00 32.65 ? 192 TRP A NE1 1 ATOM 1498 C CE2 . TRP A 1 192 ? 69.229 5.278 -22.416 1.00 32.90 ? 192 TRP A CE2 1 ATOM 1499 C CE3 . TRP A 1 192 ? 68.112 3.438 -23.625 1.00 31.63 ? 192 TRP A CE3 1 ATOM 1500 C CZ2 . TRP A 1 192 ? 68.132 6.111 -22.551 1.00 32.61 ? 192 TRP A CZ2 1 ATOM 1501 C CZ3 . TRP A 1 192 ? 67.013 4.287 -23.755 1.00 31.89 ? 192 TRP A CZ3 1 ATOM 1502 C CH2 . TRP A 1 192 ? 67.025 5.593 -23.232 1.00 32.97 ? 192 TRP A CH2 1 ATOM 1503 N N . LEU A 1 193 ? 72.636 1.209 -20.335 1.00 40.03 ? 193 LEU A N 1 ATOM 1504 C CA . LEU A 1 193 ? 73.193 1.397 -18.993 1.00 43.26 ? 193 LEU A CA 1 ATOM 1505 C C . LEU A 1 193 ? 74.234 2.498 -18.920 1.00 44.78 ? 193 LEU A C 1 ATOM 1506 O O . LEU A 1 193 ? 74.844 2.851 -19.917 1.00 44.70 ? 193 LEU A O 1 ATOM 1507 C CB . LEU A 1 193 ? 73.802 0.100 -18.477 1.00 45.43 ? 193 LEU A CB 1 ATOM 1508 C CG . LEU A 1 193 ? 72.988 -1.183 -18.577 1.00 48.51 ? 193 LEU A CG 1 ATOM 1509 C CD1 . LEU A 1 193 ? 73.953 -2.358 -18.554 1.00 51.89 ? 193 LEU A CD1 1 ATOM 1510 C CD2 . LEU A 1 193 ? 71.942 -1.282 -17.466 1.00 49.10 ? 193 LEU A CD2 1 ATOM 1511 N N . SER A 1 194 ? 74.436 3.015 -17.714 1.00 47.22 ? 194 SER A N 1 ATOM 1512 C CA . SER A 1 194 ? 75.288 4.165 -17.467 1.00 49.81 ? 194 SER A CA 1 ATOM 1513 C C . SER A 1 194 ? 75.440 4.354 -15.952 1.00 54.16 ? 194 SER A C 1 ATOM 1514 O O . SER A 1 194 ? 74.571 3.940 -15.177 1.00 56.94 ? 194 SER A O 1 ATOM 1515 C CB . SER A 1 194 ? 74.664 5.411 -18.088 1.00 49.28 ? 194 SER A CB 1 ATOM 1516 O OG . SER A 1 194 ? 73.441 5.717 -17.444 1.00 50.20 ? 194 SER A OG 1 ATOM 1517 N N . SER A 1 195 ? 76.535 4.979 -15.534 1.00 54.99 ? 195 SER A N 1 ATOM 1518 C CA . SER A 1 195 ? 76.813 5.157 -14.115 1.00 58.39 ? 195 SER A CA 1 ATOM 1519 C C . SER A 1 195 ? 77.086 6.620 -13.803 1.00 59.92 ? 195 SER A C 1 ATOM 1520 O O . SER A 1 195 ? 77.192 7.430 -14.720 1.00 60.71 ? 195 SER A O 1 ATOM 1521 C CB . SER A 1 195 ? 78.000 4.286 -13.696 1.00 61.65 ? 195 SER A CB 1 ATOM 1522 O OG . SER A 1 195 ? 79.175 4.640 -14.405 1.00 63.68 ? 195 SER A OG 1 ATOM 1523 N N . VAL A 1 196 ? 77.201 6.950 -12.516 1.00 63.40 ? 196 VAL A N 1 ATOM 1524 C CA . VAL A 1 196 ? 77.425 8.334 -12.075 1.00 67.54 ? 196 VAL A CA 1 ATOM 1525 C C . VAL A 1 196 ? 77.844 8.412 -10.590 1.00 71.74 ? 196 VAL A C 1 ATOM 1526 O O . VAL A 1 196 ? 77.376 7.614 -9.770 1.00 72.44 ? 196 VAL A O 1 ATOM 1527 C CB . VAL A 1 196 ? 76.177 9.237 -12.380 1.00 66.66 ? 196 VAL A CB 1 ATOM 1528 C CG1 . VAL A 1 196 ? 75.008 8.963 -11.409 1.00 65.02 ? 196 VAL A CG1 1 ATOM 1529 C CG2 . VAL A 1 196 ? 76.560 10.716 -12.405 1.00 70.01 ? 196 VAL A CG2 1 ATOM 1530 N N . PRO A 1 197 ? 78.750 9.353 -10.243 1.00 75.86 ? 197 PRO A N 1 ATOM 1531 C CA . PRO A 1 197 ? 79.070 9.548 -8.822 1.00 75.41 ? 197 PRO A CA 1 ATOM 1532 C C . PRO A 1 197 ? 78.146 10.557 -8.135 1.00 70.58 ? 197 PRO A C 1 ATOM 1533 O O . PRO A 1 197 ? 77.777 10.362 -6.975 1.00 66.12 ? 197 PRO A O 1 ATOM 1534 C CB . PRO A 1 197 ? 80.511 10.065 -8.852 1.00 75.90 ? 197 PRO A CB 1 ATOM 1535 C CG . PRO A 1 197 ? 80.636 10.765 -10.170 1.00 77.25 ? 197 PRO A CG 1 ATOM 1536 C CD . PRO A 1 197 ? 79.669 10.101 -11.127 1.00 77.01 ? 197 PRO A CD 1 ATOM 1537 N N . ARG A 1 204 ? 79.111 5.230 -5.845 1.00 71.32 ? 204 ARG A N 1 ATOM 1538 C CA . ARG A 1 204 ? 78.841 5.255 -7.280 1.00 78.71 ? 204 ARG A CA 1 ATOM 1539 C C . ARG A 1 204 ? 77.447 4.685 -7.613 1.00 79.34 ? 204 ARG A C 1 ATOM 1540 O O . ARG A 1 204 ? 77.049 3.639 -7.090 1.00 75.22 ? 204 ARG A O 1 ATOM 1541 C CB . ARG A 1 204 ? 79.951 4.510 -8.037 1.00 81.36 ? 204 ARG A CB 1 ATOM 1542 C CG . ARG A 1 204 ? 79.826 4.559 -9.554 1.00 86.43 ? 204 ARG A CG 1 ATOM 1543 C CD . ARG A 1 204 ? 81.176 4.387 -10.243 1.00 87.29 ? 204 ARG A CD 1 ATOM 1544 N NE . ARG A 1 204 ? 81.145 4.823 -11.644 1.00 87.68 ? 204 ARG A NE 1 ATOM 1545 C CZ . ARG A 1 204 ? 81.156 6.096 -12.048 1.00 86.48 ? 204 ARG A CZ 1 ATOM 1546 N NH1 . ARG A 1 204 ? 81.185 7.092 -11.165 1.00 82.59 ? 204 ARG A NH1 1 ATOM 1547 N NH2 . ARG A 1 204 ? 81.129 6.376 -13.344 1.00 83.68 ? 204 ARG A NH2 1 ATOM 1548 N N . GLN A 1 205 ? 76.711 5.372 -8.486 1.00 78.12 ? 205 GLN A N 1 ATOM 1549 C CA . GLN A 1 205 ? 75.336 4.968 -8.792 1.00 70.22 ? 205 GLN A CA 1 ATOM 1550 C C . GLN A 1 205 ? 75.114 4.448 -10.216 1.00 63.53 ? 205 GLN A C 1 ATOM 1551 O O . GLN A 1 205 ? 75.507 5.072 -11.199 1.00 61.47 ? 205 GLN A O 1 ATOM 1552 C CB . GLN A 1 205 ? 74.353 6.086 -8.464 1.00 70.48 ? 205 GLN A CB 1 ATOM 1553 C CG . GLN A 1 205 ? 73.099 5.562 -7.802 1.00 75.15 ? 205 GLN A CG 1 ATOM 1554 C CD . GLN A 1 205 ? 72.198 6.664 -7.301 1.00 76.77 ? 205 GLN A CD 1 ATOM 1555 O OE1 . GLN A 1 205 ? 71.400 7.218 -8.061 1.00 80.41 ? 205 GLN A OE1 1 ATOM 1556 N NE2 . GLN A 1 205 ? 72.308 6.984 -6.014 1.00 71.60 ? 205 GLN A NE2 1 ATOM 1557 N N . LEU A 1 206 ? 74.474 3.291 -10.298 1.00 57.50 ? 206 LEU A N 1 ATOM 1558 C CA . LEU A 1 206 ? 74.180 2.641 -11.561 1.00 55.61 ? 206 LEU A CA 1 ATOM 1559 C C . LEU A 1 206 ? 72.750 2.934 -11.989 1.00 55.03 ? 206 LEU A C 1 ATOM 1560 O O . LEU A 1 206 ? 71.857 3.084 -11.150 1.00 54.56 ? 206 LEU A O 1 ATOM 1561 C CB . LEU A 1 206 ? 74.380 1.134 -11.432 1.00 55.85 ? 206 LEU A CB 1 ATOM 1562 C CG . LEU A 1 206 ? 75.717 0.533 -11.856 1.00 57.70 ? 206 LEU A CG 1 ATOM 1563 C CD1 . LEU A 1 206 ? 76.903 1.136 -11.119 1.00 57.82 ? 206 LEU A CD1 1 ATOM 1564 C CD2 . LEU A 1 206 ? 75.666 -0.960 -11.636 1.00 60.07 ? 206 LEU A CD2 1 ATOM 1565 N N . VAL A 1 207 ? 72.540 3.001 -13.301 1.00 52.03 ? 207 VAL A N 1 ATOM 1566 C CA . VAL A 1 207 ? 71.280 3.455 -13.863 1.00 48.02 ? 207 VAL A CA 1 ATOM 1567 C C . VAL A 1 207 ? 70.852 2.544 -15.009 1.00 46.40 ? 207 VAL A C 1 ATOM 1568 O O . VAL A 1 207 ? 71.602 2.309 -15.957 1.00 45.81 ? 207 VAL A O 1 ATOM 1569 C CB . VAL A 1 207 ? 71.390 4.932 -14.350 1.00 48.13 ? 207 VAL A CB 1 ATOM 1570 C CG1 . VAL A 1 207 ? 70.088 5.409 -14.951 1.00 49.36 ? 207 VAL A CG1 1 ATOM 1571 C CG2 . VAL A 1 207 ? 71.787 5.853 -13.207 1.00 47.02 ? 207 VAL A CG2 1 ATOM 1572 N N . CYS A 1 208 ? 69.636 2.030 -14.911 1.00 46.03 ? 208 CYS A N 1 ATOM 1573 C CA . CYS A 1 208 ? 69.050 1.257 -15.994 1.00 47.00 ? 208 CYS A CA 1 ATOM 1574 C C . CYS A 1 208 ? 67.960 2.057 -16.707 1.00 44.89 ? 208 CYS A C 1 ATOM 1575 O O . CYS A 1 208 ? 66.925 2.369 -16.109 1.00 43.86 ? 208 CYS A O 1 ATOM 1576 C CB . CYS A 1 208 ? 68.462 -0.039 -15.459 1.00 49.65 ? 208 CYS A CB 1 ATOM 1577 S SG . CYS A 1 208 ? 68.252 -1.264 -16.731 1.00 52.11 ? 208 CYS A SG 1 ATOM 1578 N N . HIS A 1 209 ? 68.206 2.373 -17.979 1.00 41.01 ? 209 HIS A N 1 ATOM 1579 C CA . HIS A 1 209 ? 67.317 3.207 -18.782 1.00 37.66 ? 209 HIS A CA 1 ATOM 1580 C C . HIS A 1 209 ? 66.410 2.358 -19.613 1.00 36.42 ? 209 HIS A C 1 ATOM 1581 O O . HIS A 1 209 ? 66.875 1.569 -20.440 1.00 36.04 ? 209 HIS A O 1 ATOM 1582 C CB . HIS A 1 209 ? 68.113 4.096 -19.729 1.00 38.51 ? 209 HIS A CB 1 ATOM 1583 C CG . HIS A 1 209 ? 69.081 5.037 -19.046 1.00 40.29 ? 209 HIS A CG 1 ATOM 1584 N ND1 . HIS A 1 209 ? 68.883 6.366 -18.997 1.00 40.73 ? 209 HIS A ND1 1 ATOM 1585 C CD2 . HIS A 1 209 ? 70.298 4.799 -18.410 1.00 40.48 ? 209 HIS A CD2 1 ATOM 1586 C CE1 . HIS A 1 209 ? 69.906 6.948 -18.345 1.00 41.51 ? 209 HIS A CE1 1 ATOM 1587 N NE2 . HIS A 1 209 ? 70.771 5.987 -17.990 1.00 41.12 ? 209 HIS A NE2 1 ATOM 1588 N N . VAL A 1 210 ? 65.104 2.515 -19.419 1.00 33.60 ? 210 VAL A N 1 ATOM 1589 C CA . VAL A 1 210 ? 64.132 1.795 -20.229 1.00 31.61 ? 210 VAL A CA 1 ATOM 1590 C C . VAL A 1 210 ? 63.216 2.816 -20.915 1.00 31.31 ? 210 VAL A C 1 ATOM 1591 O O . VAL A 1 210 ? 62.627 3.676 -20.246 1.00 31.53 ? 210 VAL A O 1 ATOM 1592 C CB . VAL A 1 210 ? 63.305 0.810 -19.360 1.00 31.16 ? 210 VAL A CB 1 ATOM 1593 C CG1 . VAL A 1 210 ? 62.764 -0.338 -20.208 1.00 29.71 ? 210 VAL A CG1 1 ATOM 1594 C CG2 . VAL A 1 210 ? 64.144 0.272 -18.198 1.00 30.06 ? 210 VAL A CG2 1 ATOM 1595 N N . SER A 1 211 ? 63.094 2.734 -22.237 1.00 29.45 ? 211 SER A N 1 ATOM 1596 C CA . SER A 1 211 ? 62.334 3.737 -22.980 1.00 28.92 ? 211 SER A CA 1 ATOM 1597 C C . SER A 1 211 ? 61.670 3.197 -24.242 1.00 28.25 ? 211 SER A C 1 ATOM 1598 O O . SER A 1 211 ? 62.214 2.315 -24.911 1.00 25.73 ? 211 SER A O 1 ATOM 1599 C CB . SER A 1 211 ? 63.235 4.917 -23.354 1.00 30.66 ? 211 SER A CB 1 ATOM 1600 O OG . SER A 1 211 ? 62.510 5.943 -24.019 1.00 31.86 ? 211 SER A OG 1 ATOM 1601 N N . GLY A 1 212 ? 60.497 3.756 -24.559 1.00 28.68 ? 212 GLY A N 1 ATOM 1602 C CA . GLY A 1 212 ? 59.732 3.389 -25.756 1.00 27.98 ? 212 GLY A CA 1 ATOM 1603 C C . GLY A 1 212 ? 58.619 2.374 -25.533 1.00 27.90 ? 212 GLY A C 1 ATOM 1604 O O . GLY A 1 212 ? 58.008 1.917 -26.506 1.00 29.85 ? 212 GLY A O 1 ATOM 1605 N N . PHE A 1 213 ? 58.323 2.029 -24.277 1.00 25.69 ? 213 PHE A N 1 ATOM 1606 C CA . PHE A 1 213 ? 57.338 0.962 -24.015 1.00 26.73 ? 213 PHE A CA 1 ATOM 1607 C C . PHE A 1 213 ? 55.873 1.416 -23.869 1.00 27.88 ? 213 PHE A C 1 ATOM 1608 O O . PHE A 1 213 ? 55.579 2.504 -23.355 1.00 28.31 ? 213 PHE A O 1 ATOM 1609 C CB . PHE A 1 213 ? 57.748 0.053 -22.839 1.00 24.35 ? 213 PHE A CB 1 ATOM 1610 C CG . PHE A 1 213 ? 57.811 0.756 -21.521 1.00 23.66 ? 213 PHE A CG 1 ATOM 1611 C CD1 . PHE A 1 213 ? 58.967 1.405 -21.119 1.00 22.86 ? 213 PHE A CD1 1 ATOM 1612 C CD2 . PHE A 1 213 ? 56.710 0.772 -20.671 1.00 23.79 ? 213 PHE A CD2 1 ATOM 1613 C CE1 . PHE A 1 213 ? 59.019 2.065 -19.895 1.00 22.81 ? 213 PHE A CE1 1 ATOM 1614 C CE2 . PHE A 1 213 ? 56.760 1.428 -19.433 1.00 23.11 ? 213 PHE A CE2 1 ATOM 1615 C CZ . PHE A 1 213 ? 57.911 2.077 -19.052 1.00 22.80 ? 213 PHE A CZ 1 ATOM 1616 N N . TYR A 1 214 ? 54.969 0.564 -24.349 1.00 29.06 ? 214 TYR A N 1 ATOM 1617 C CA . TYR A 1 214 ? 53.533 0.720 -24.130 1.00 29.79 ? 214 TYR A CA 1 ATOM 1618 C C . TYR A 1 214 ? 52.856 -0.642 -24.011 1.00 28.84 ? 214 TYR A C 1 ATOM 1619 O O . TYR A 1 214 ? 53.088 -1.511 -24.850 1.00 28.79 ? 214 TYR A O 1 ATOM 1620 C CB . TYR A 1 214 ? 52.882 1.535 -25.251 1.00 30.57 ? 214 TYR A CB 1 ATOM 1621 C CG . TYR A 1 214 ? 51.547 2.086 -24.829 1.00 30.78 ? 214 TYR A CG 1 ATOM 1622 C CD1 . TYR A 1 214 ? 50.363 1.436 -25.177 1.00 30.76 ? 214 TYR A CD1 1 ATOM 1623 C CD2 . TYR A 1 214 ? 51.466 3.239 -24.038 1.00 30.97 ? 214 TYR A CD2 1 ATOM 1624 C CE1 . TYR A 1 214 ? 49.113 1.929 -24.760 1.00 30.27 ? 214 TYR A CE1 1 ATOM 1625 C CE2 . TYR A 1 214 ? 50.217 3.745 -23.614 1.00 30.96 ? 214 TYR A CE2 1 ATOM 1626 C CZ . TYR A 1 214 ? 49.051 3.080 -23.985 1.00 29.86 ? 214 TYR A CZ 1 ATOM 1627 O OH . TYR A 1 214 ? 47.836 3.558 -23.585 1.00 28.57 ? 214 TYR A OH 1 ATOM 1628 N N . PRO A 1 215 ? 51.976 -0.820 -23.006 1.00 28.90 ? 215 PRO A N 1 ATOM 1629 C CA . PRO A 1 215 ? 51.487 0.191 -22.080 1.00 29.41 ? 215 PRO A CA 1 ATOM 1630 C C . PRO A 1 215 ? 52.352 0.366 -20.853 1.00 31.27 ? 215 PRO A C 1 ATOM 1631 O O . PRO A 1 215 ? 53.448 -0.183 -20.784 1.00 30.82 ? 215 PRO A O 1 ATOM 1632 C CB . PRO A 1 215 ? 50.109 -0.341 -21.677 1.00 28.29 ? 215 PRO A CB 1 ATOM 1633 C CG . PRO A 1 215 ? 50.228 -1.800 -21.783 1.00 27.70 ? 215 PRO A CG 1 ATOM 1634 C CD . PRO A 1 215 ? 51.282 -2.107 -22.815 1.00 28.79 ? 215 PRO A CD 1 ATOM 1635 N N . LYS A 1 216 ? 51.814 1.108 -19.887 1.00 34.17 ? 216 LYS A N 1 ATOM 1636 C CA . LYS A 1 216 ? 52.550 1.598 -18.732 1.00 35.39 ? 216 LYS A CA 1 ATOM 1637 C C . LYS A 1 216 ? 53.113 0.539 -17.783 1.00 37.82 ? 216 LYS A C 1 ATOM 1638 O O . LYS A 1 216 ? 54.248 0.699 -17.326 1.00 42.17 ? 216 LYS A O 1 ATOM 1639 C CB . LYS A 1 216 ? 51.690 2.597 -17.959 1.00 37.39 ? 216 LYS A CB 1 ATOM 1640 C CG . LYS A 1 216 ? 52.470 3.633 -17.180 1.00 38.23 ? 216 LYS A CG 1 ATOM 1641 C CD . LYS A 1 216 ? 51.534 4.650 -16.552 1.00 38.96 ? 216 LYS A CD 1 ATOM 1642 C CE . LYS A 1 216 ? 52.289 5.912 -16.171 1.00 41.24 ? 216 LYS A CE 1 ATOM 1643 N NZ . LYS A 1 216 ? 51.641 6.674 -15.061 1.00 43.07 ? 216 LYS A NZ 1 ATOM 1644 N N . PRO A 1 217 ? 52.347 -0.541 -17.468 1.00 38.00 ? 217 PRO A N 1 ATOM 1645 C CA . PRO A 1 217 ? 52.945 -1.499 -16.513 1.00 37.94 ? 217 PRO A CA 1 ATOM 1646 C C . PRO A 1 217 ? 54.260 -2.136 -17.010 1.00 37.07 ? 217 PRO A C 1 ATOM 1647 O O . PRO A 1 217 ? 54.306 -2.718 -18.102 1.00 35.78 ? 217 PRO A O 1 ATOM 1648 C CB . PRO A 1 217 ? 51.837 -2.547 -16.330 1.00 37.24 ? 217 PRO A CB 1 ATOM 1649 C CG . PRO A 1 217 ? 50.572 -1.817 -16.705 1.00 35.66 ? 217 PRO A CG 1 ATOM 1650 C CD . PRO A 1 217 ? 50.974 -0.942 -17.835 1.00 35.40 ? 217 PRO A CD 1 ATOM 1651 N N . VAL A 1 218 ? 55.317 -1.994 -16.209 1.00 37.07 ? 218 VAL A N 1 ATOM 1652 C CA . VAL A 1 218 ? 56.645 -2.532 -16.536 1.00 38.06 ? 218 VAL A CA 1 ATOM 1653 C C . VAL A 1 218 ? 57.352 -3.038 -15.267 1.00 40.07 ? 218 VAL A C 1 ATOM 1654 O O . VAL A 1 218 ? 57.117 -2.522 -14.166 1.00 38.22 ? 218 VAL A O 1 ATOM 1655 C CB . VAL A 1 218 ? 57.517 -1.464 -17.276 1.00 37.33 ? 218 VAL A CB 1 ATOM 1656 C CG1 . VAL A 1 218 ? 57.958 -0.354 -16.325 1.00 36.71 ? 218 VAL A CG1 1 ATOM 1657 C CG2 . VAL A 1 218 ? 58.716 -2.088 -17.972 1.00 35.89 ? 218 VAL A CG2 1 ATOM 1658 N N . TRP A 1 219 ? 58.208 -4.049 -15.426 1.00 43.52 ? 219 TRP A N 1 ATOM 1659 C CA . TRP A 1 219 ? 59.017 -4.569 -14.319 1.00 44.43 ? 219 TRP A CA 1 ATOM 1660 C C . TRP A 1 219 ? 60.489 -4.396 -14.588 1.00 43.52 ? 219 TRP A C 1 ATOM 1661 O O . TRP A 1 219 ? 61.002 -4.895 -15.592 1.00 43.95 ? 219 TRP A O 1 ATOM 1662 C CB . TRP A 1 219 ? 58.681 -6.030 -14.092 1.00 47.51 ? 219 TRP A CB 1 ATOM 1663 C CG . TRP A 1 219 ? 59.283 -6.619 -12.839 1.00 52.36 ? 219 TRP A CG 1 ATOM 1664 C CD1 . TRP A 1 219 ? 58.705 -6.694 -11.567 1.00 52.60 ? 219 TRP A CD1 1 ATOM 1665 C CD2 . TRP A 1 219 ? 60.603 -7.261 -12.698 1.00 53.54 ? 219 TRP A CD2 1 ATOM 1666 N NE1 . TRP A 1 219 ? 59.553 -7.312 -10.680 1.00 52.64 ? 219 TRP A NE1 1 ATOM 1667 C CE2 . TRP A 1 219 ? 60.708 -7.678 -11.292 1.00 54.12 ? 219 TRP A CE2 1 ATOM 1668 C CE3 . TRP A 1 219 ? 61.670 -7.516 -13.560 1.00 54.48 ? 219 TRP A CE3 1 ATOM 1669 C CZ2 . TRP A 1 219 ? 61.840 -8.321 -10.798 1.00 54.78 ? 219 TRP A CZ2 1 ATOM 1670 C CZ3 . TRP A 1 219 ? 62.805 -8.166 -13.049 1.00 56.13 ? 219 TRP A CZ3 1 ATOM 1671 C CH2 . TRP A 1 219 ? 62.885 -8.558 -11.701 1.00 54.63 ? 219 TRP A CH2 1 ATOM 1672 N N . VAL A 1 220 ? 61.178 -3.675 -13.706 1.00 43.35 ? 220 VAL A N 1 ATOM 1673 C CA . VAL A 1 220 ? 62.617 -3.409 -13.865 1.00 48.71 ? 220 VAL A CA 1 ATOM 1674 C C . VAL A 1 220 ? 63.380 -3.573 -12.550 1.00 52.31 ? 220 VAL A C 1 ATOM 1675 O O . VAL A 1 220 ? 63.107 -2.869 -11.569 1.00 51.75 ? 220 VAL A O 1 ATOM 1676 C CB . VAL A 1 220 ? 62.903 -1.984 -14.417 1.00 50.04 ? 220 VAL A CB 1 ATOM 1677 C CG1 . VAL A 1 220 ? 64.398 -1.784 -14.650 1.00 50.20 ? 220 VAL A CG1 1 ATOM 1678 C CG2 . VAL A 1 220 ? 62.144 -1.731 -15.711 1.00 49.76 ? 220 VAL A CG2 1 ATOM 1679 N N . MET A 1 221 ? 64.348 -4.490 -12.548 1.00 57.29 ? 221 MET A N 1 ATOM 1680 C CA . MET A 1 221 ? 65.139 -4.783 -11.349 1.00 61.23 ? 221 MET A CA 1 ATOM 1681 C C . MET A 1 221 ? 66.615 -5.019 -11.674 1.00 63.96 ? 221 MET A C 1 ATOM 1682 O O . MET A 1 221 ? 66.957 -5.621 -12.712 1.00 59.68 ? 221 MET A O 1 ATOM 1683 C CB . MET A 1 221 ? 64.573 -6.017 -10.631 1.00 63.27 ? 221 MET A CB 1 ATOM 1684 C CG . MET A 1 221 ? 64.717 -6.016 -9.118 1.00 63.41 ? 221 MET A CG 1 ATOM 1685 S SD . MET A 1 221 ? 63.815 -4.659 -8.330 1.00 70.11 ? 221 MET A SD 1 ATOM 1686 C CE . MET A 1 221 ? 62.103 -5.031 -8.739 1.00 66.77 ? 221 MET A CE 1 ATOM 1687 N N . TRP A 1 222 ? 67.477 -4.544 -10.772 1.00 64.22 ? 222 TRP A N 1 ATOM 1688 C CA . TRP A 1 222 ? 68.909 -4.841 -10.820 1.00 64.84 ? 222 TRP A CA 1 ATOM 1689 C C . TRP A 1 222 ? 69.192 -6.199 -10.235 1.00 66.57 ? 222 TRP A C 1 ATOM 1690 O O . TRP A 1 222 ? 68.601 -6.593 -9.224 1.00 63.94 ? 222 TRP A O 1 ATOM 1691 C CB . TRP A 1 222 ? 69.700 -3.780 -10.074 1.00 63.38 ? 222 TRP A CB 1 ATOM 1692 C CG . TRP A 1 222 ? 70.004 -2.544 -10.884 1.00 61.29 ? 222 TRP A CG 1 ATOM 1693 C CD1 . TRP A 1 222 ? 69.378 -1.300 -10.807 1.00 60.92 ? 222 TRP A CD1 1 ATOM 1694 C CD2 . TRP A 1 222 ? 71.044 -2.385 -11.911 1.00 61.68 ? 222 TRP A CD2 1 ATOM 1695 N NE1 . TRP A 1 222 ? 69.934 -0.415 -11.692 1.00 61.28 ? 222 TRP A NE1 1 ATOM 1696 C CE2 . TRP A 1 222 ? 70.938 -0.999 -12.390 1.00 62.62 ? 222 TRP A CE2 1 ATOM 1697 C CE3 . TRP A 1 222 ? 72.013 -3.219 -12.467 1.00 59.69 ? 222 TRP A CE3 1 ATOM 1698 C CZ2 . TRP A 1 222 ? 71.778 -0.495 -13.383 1.00 61.02 ? 222 TRP A CZ2 1 ATOM 1699 C CZ3 . TRP A 1 222 ? 72.847 -2.700 -13.468 1.00 58.60 ? 222 TRP A CZ3 1 ATOM 1700 C CH2 . TRP A 1 222 ? 72.732 -1.370 -13.912 1.00 58.68 ? 222 TRP A CH2 1 ATOM 1701 N N . MET A 1 223 ? 70.118 -6.923 -10.857 1.00 73.34 ? 223 MET A N 1 ATOM 1702 C CA . MET A 1 223 ? 70.343 -8.334 -10.531 1.00 79.41 ? 223 MET A CA 1 ATOM 1703 C C . MET A 1 223 ? 71.803 -8.802 -10.560 1.00 80.83 ? 223 MET A C 1 ATOM 1704 O O . MET A 1 223 ? 72.475 -8.723 -11.597 1.00 82.74 ? 223 MET A O 1 ATOM 1705 C CB . MET A 1 223 ? 69.521 -9.213 -11.480 1.00 81.31 ? 223 MET A CB 1 ATOM 1706 C CG . MET A 1 223 ? 68.118 -9.550 -10.991 1.00 81.30 ? 223 MET A CG 1 ATOM 1707 S SD . MET A 1 223 ? 67.135 -10.350 -12.273 1.00 80.97 ? 223 MET A SD 1 ATOM 1708 C CE . MET A 1 223 ? 68.278 -11.545 -12.990 1.00 77.77 ? 223 MET A CE 1 ATOM 1709 N N . ARG A 1 224 ? 72.282 -9.304 -9.423 1.00 81.25 ? 224 ARG A N 1 ATOM 1710 C CA . ARG A 1 224 ? 73.526 -10.076 -9.396 1.00 79.69 ? 224 ARG A CA 1 ATOM 1711 C C . ARG A 1 224 ? 73.200 -11.544 -9.695 1.00 78.78 ? 224 ARG A C 1 ATOM 1712 O O . ARG A 1 224 ? 72.629 -12.249 -8.849 1.00 76.39 ? 224 ARG A O 1 ATOM 1713 C CB . ARG A 1 224 ? 74.261 -9.931 -8.054 1.00 76.45 ? 224 ARG A CB 1 ATOM 1714 C CG . ARG A 1 224 ? 75.626 -10.623 -8.032 1.00 73.88 ? 224 ARG A CG 1 ATOM 1715 C CD . ARG A 1 224 ? 76.523 -10.107 -6.932 1.00 67.54 ? 224 ARG A CD 1 ATOM 1716 N NE . ARG A 1 224 ? 77.198 -8.867 -7.306 1.00 64.13 ? 224 ARG A NE 1 ATOM 1717 C CZ . ARG A 1 224 ? 77.025 -7.697 -6.694 1.00 63.34 ? 224 ARG A CZ 1 ATOM 1718 N NH1 . ARG A 1 224 ? 76.188 -7.586 -5.661 1.00 57.39 ? 224 ARG A NH1 1 ATOM 1719 N NH2 . ARG A 1 224 ? 77.697 -6.631 -7.114 1.00 61.71 ? 224 ARG A NH2 1 ATOM 1720 N N . GLY A 1 225 ? 73.556 -11.988 -10.903 1.00 75.53 ? 225 GLY A N 1 ATOM 1721 C CA . GLY A 1 225 ? 73.229 -13.336 -11.372 1.00 75.49 ? 225 GLY A CA 1 ATOM 1722 C C . GLY A 1 225 ? 71.728 -13.493 -11.498 1.00 78.51 ? 225 GLY A C 1 ATOM 1723 O O . GLY A 1 225 ? 71.151 -13.195 -12.550 1.00 82.78 ? 225 GLY A O 1 ATOM 1724 N N . ASP A 1 226 ? 71.102 -13.956 -10.415 1.00 77.98 ? 226 ASP A N 1 ATOM 1725 C CA . ASP A 1 226 ? 69.638 -13.957 -10.285 1.00 76.99 ? 226 ASP A CA 1 ATOM 1726 C C . ASP A 1 226 ? 69.171 -13.710 -8.843 1.00 72.71 ? 226 ASP A C 1 ATOM 1727 O O . ASP A 1 226 ? 68.224 -14.336 -8.365 1.00 67.97 ? 226 ASP A O 1 ATOM 1728 C CB . ASP A 1 226 ? 68.997 -15.225 -10.895 1.00 79.43 ? 226 ASP A CB 1 ATOM 1729 C CG . ASP A 1 226 ? 69.599 -16.527 -10.363 1.00 83.12 ? 226 ASP A CG 1 ATOM 1730 O OD1 . ASP A 1 226 ? 69.464 -17.551 -11.066 1.00 84.78 ? 226 ASP A OD1 1 ATOM 1731 O OD2 . ASP A 1 226 ? 70.194 -16.545 -9.259 1.00 84.37 ? 226 ASP A OD2 1 ATOM 1732 N N . GLN A 1 227 ? 69.849 -12.793 -8.161 1.00 73.90 ? 227 GLN A N 1 ATOM 1733 C CA . GLN A 1 227 ? 69.423 -12.333 -6.838 1.00 78.48 ? 227 GLN A CA 1 ATOM 1734 C C . GLN A 1 227 ? 68.959 -10.877 -6.964 1.00 76.91 ? 227 GLN A C 1 ATOM 1735 O O . GLN A 1 227 ? 69.780 -9.953 -7.050 1.00 77.73 ? 227 GLN A O 1 ATOM 1736 C CB . GLN A 1 227 ? 70.552 -12.456 -5.795 1.00 81.71 ? 227 GLN A CB 1 ATOM 1737 C CG . GLN A 1 227 ? 71.460 -13.688 -5.935 1.00 87.63 ? 227 GLN A CG 1 ATOM 1738 C CD . GLN A 1 227 ? 70.849 -14.970 -5.377 1.00 91.36 ? 227 GLN A CD 1 ATOM 1739 O OE1 . GLN A 1 227 ? 70.495 -15.885 -6.136 1.00 90.92 ? 227 GLN A OE1 1 ATOM 1740 N NE2 . GLN A 1 227 ? 70.733 -15.041 -4.043 1.00 92.83 ? 227 GLN A NE2 1 ATOM 1741 N N . GLU A 1 228 ? 67.642 -10.684 -6.996 1.00 72.24 ? 228 GLU A N 1 ATOM 1742 C CA . GLU A 1 228 ? 67.050 -9.356 -7.144 1.00 67.05 ? 228 GLU A CA 1 ATOM 1743 C C . GLU A 1 228 ? 67.617 -8.403 -6.103 1.00 66.66 ? 228 GLU A C 1 ATOM 1744 O O . GLU A 1 228 ? 67.290 -8.507 -4.919 1.00 66.56 ? 228 GLU A O 1 ATOM 1745 C CB . GLU A 1 228 ? 65.526 -9.421 -6.999 1.00 63.81 ? 228 GLU A CB 1 ATOM 1746 C CG . GLU A 1 228 ? 64.785 -10.091 -8.156 1.00 62.86 ? 228 GLU A CG 1 ATOM 1747 C CD . GLU A 1 228 ? 63.273 -10.218 -7.913 1.00 60.77 ? 228 GLU A CD 1 ATOM 1748 O OE1 . GLU A 1 228 ? 62.639 -11.013 -8.640 1.00 58.11 ? 228 GLU A OE1 1 ATOM 1749 O OE2 . GLU A 1 228 ? 62.722 -9.534 -7.012 1.00 55.31 ? 228 GLU A OE2 1 ATOM 1750 N N . GLN A 1 229 ? 68.475 -7.484 -6.538 1.00 64.45 ? 229 GLN A N 1 ATOM 1751 C CA . GLN A 1 229 ? 69.026 -6.496 -5.623 1.00 66.60 ? 229 GLN A CA 1 ATOM 1752 C C . GLN A 1 229 ? 67.906 -5.710 -4.968 1.00 66.86 ? 229 GLN A C 1 ATOM 1753 O O . GLN A 1 229 ? 67.059 -5.127 -5.647 1.00 69.27 ? 229 GLN A O 1 ATOM 1754 C CB . GLN A 1 229 ? 70.013 -5.552 -6.322 1.00 70.90 ? 229 GLN A CB 1 ATOM 1755 C CG . GLN A 1 229 ? 71.298 -6.226 -6.826 1.00 73.05 ? 229 GLN A CG 1 ATOM 1756 C CD . GLN A 1 229 ? 71.922 -7.164 -5.806 1.00 70.79 ? 229 GLN A CD 1 ATOM 1757 O OE1 . GLN A 1 229 ? 72.086 -8.353 -6.070 1.00 72.78 ? 229 GLN A OE1 1 ATOM 1758 N NE2 . GLN A 1 229 ? 72.257 -6.636 -4.633 1.00 68.36 ? 229 GLN A NE2 1 ATOM 1759 N N . GLN A 1 230 ? 67.900 -5.726 -3.640 1.00 66.21 ? 230 GLN A N 1 ATOM 1760 C CA . GLN A 1 230 ? 66.884 -5.048 -2.857 1.00 64.16 ? 230 GLN A CA 1 ATOM 1761 C C . GLN A 1 230 ? 66.994 -3.528 -2.996 1.00 64.58 ? 230 GLN A C 1 ATOM 1762 O O . GLN A 1 230 ? 65.998 -2.818 -2.829 1.00 66.47 ? 230 GLN A O 1 ATOM 1763 C CB . GLN A 1 230 ? 66.979 -5.470 -1.386 1.00 63.51 ? 230 GLN A CB 1 ATOM 1764 N N . GLY A 1 231 ? 68.193 -3.041 -3.318 1.00 61.48 ? 231 GLY A N 1 ATOM 1765 C CA . GLY A 1 231 ? 68.488 -1.600 -3.332 1.00 60.31 ? 231 GLY A CA 1 ATOM 1766 C C . GLY A 1 231 ? 67.925 -0.779 -4.486 1.00 59.95 ? 231 GLY A C 1 ATOM 1767 O O . GLY A 1 231 ? 67.857 0.459 -4.403 1.00 57.92 ? 231 GLY A O 1 ATOM 1768 N N . THR A 1 232 ? 67.537 -1.464 -5.563 1.00 58.95 ? 232 THR A N 1 ATOM 1769 C CA . THR A 1 232 ? 66.888 -0.842 -6.725 1.00 60.19 ? 232 THR A CA 1 ATOM 1770 C C . THR A 1 232 ? 65.853 0.225 -6.340 1.00 62.78 ? 232 THR A C 1 ATOM 1771 O O . THR A 1 232 ? 64.934 -0.046 -5.561 1.00 63.23 ? 232 THR A O 1 ATOM 1772 C CB . THR A 1 232 ? 66.197 -1.914 -7.586 1.00 57.28 ? 232 THR A CB 1 ATOM 1773 O OG1 . THR A 1 232 ? 67.132 -2.960 -7.886 1.00 59.42 ? 232 THR A OG1 1 ATOM 1774 C CG2 . THR A 1 232 ? 65.668 -1.321 -8.883 1.00 54.04 ? 232 THR A CG2 1 ATOM 1775 N N . HIS A 1 233 ? 66.020 1.435 -6.871 1.00 65.15 ? 233 HIS A N 1 ATOM 1776 C CA . HIS A 1 233 ? 65.031 2.500 -6.692 1.00 66.18 ? 233 HIS A CA 1 ATOM 1777 C C . HIS A 1 233 ? 64.469 2.937 -8.015 1.00 62.93 ? 233 HIS A C 1 ATOM 1778 O O . HIS A 1 233 ? 65.191 3.459 -8.869 1.00 61.13 ? 233 HIS A O 1 ATOM 1779 C CB . HIS A 1 233 ? 65.622 3.685 -5.923 1.00 72.98 ? 233 HIS A CB 1 ATOM 1780 C CG . HIS A 1 233 ? 64.683 4.878 -5.806 1.00 81.16 ? 233 HIS A CG 1 ATOM 1781 N ND1 . HIS A 1 233 ? 65.007 6.108 -6.263 1.00 82.20 ? 233 HIS A ND1 1 ATOM 1782 C CD2 . HIS A 1 233 ? 63.399 4.989 -5.262 1.00 81.10 ? 233 HIS A CD2 1 ATOM 1783 C CE1 . HIS A 1 233 ? 63.992 6.962 -6.020 1.00 80.12 ? 233 HIS A CE1 1 ATOM 1784 N NE2 . HIS A 1 233 ? 63.009 6.278 -5.408 1.00 81.53 ? 233 HIS A NE2 1 ATOM 1785 N N . ARG A 1 234 ? 63.169 2.712 -8.190 1.00 60.57 ? 234 ARG A N 1 ATOM 1786 C CA . ARG A 1 234 ? 62.448 3.123 -9.394 1.00 56.21 ? 234 ARG A CA 1 ATOM 1787 C C . ARG A 1 234 ? 62.197 4.625 -9.434 1.00 52.84 ? 234 ARG A C 1 ATOM 1788 O O . ARG A 1 234 ? 61.837 5.234 -8.423 1.00 52.74 ? 234 ARG A O 1 ATOM 1789 C CB . ARG A 1 234 ? 61.113 2.385 -9.493 1.00 57.55 ? 234 ARG A CB 1 ATOM 1790 C CG . ARG A 1 234 ? 61.177 1.087 -10.285 1.00 61.46 ? 234 ARG A CG 1 ATOM 1791 C CD . ARG A 1 234 ? 59.950 0.218 -10.051 1.00 61.51 ? 234 ARG A CD 1 ATOM 1792 N NE . ARG A 1 234 ? 58.703 0.952 -10.269 1.00 62.09 ? 234 ARG A NE 1 ATOM 1793 C CZ . ARG A 1 234 ? 57.803 0.663 -11.208 1.00 62.45 ? 234 ARG A CZ 1 ATOM 1794 N NH1 . ARG A 1 234 ? 57.988 -0.364 -12.037 1.00 56.54 ? 234 ARG A NH1 1 ATOM 1795 N NH2 . ARG A 1 234 ? 56.703 1.404 -11.307 1.00 60.36 ? 234 ARG A NH2 1 ATOM 1796 N N . GLY A 1 235 ? 62.392 5.214 -10.610 1.00 48.27 ? 235 GLY A N 1 ATOM 1797 C CA . GLY A 1 235 ? 62.036 6.606 -10.835 1.00 45.54 ? 235 GLY A CA 1 ATOM 1798 C C . GLY A 1 235 ? 60.568 6.691 -11.198 1.00 45.36 ? 235 GLY A C 1 ATOM 1799 O O . GLY A 1 235 ? 59.866 5.672 -11.233 1.00 43.79 ? 235 GLY A O 1 ATOM 1800 N N . ASP A 1 236 ? 60.088 7.901 -11.468 1.00 43.45 ? 236 ASP A N 1 ATOM 1801 C CA . ASP A 1 236 ? 58.719 8.055 -11.931 1.00 41.26 ? 236 ASP A CA 1 ATOM 1802 C C . ASP A 1 236 ? 58.635 7.657 -13.394 1.00 38.48 ? 236 ASP A C 1 ATOM 1803 O O . ASP A 1 236 ? 59.651 7.556 -14.073 1.00 37.57 ? 236 ASP A O 1 ATOM 1804 C CB . ASP A 1 236 ? 58.238 9.491 -11.747 1.00 44.60 ? 236 ASP A CB 1 ATOM 1805 C CG . ASP A 1 236 ? 58.524 10.027 -10.365 1.00 47.40 ? 236 ASP A CG 1 ATOM 1806 O OD1 . ASP A 1 236 ? 58.336 9.287 -9.377 1.00 48.86 ? 236 ASP A OD1 1 ATOM 1807 O OD2 . ASP A 1 236 ? 58.940 11.197 -10.265 1.00 49.96 ? 236 ASP A OD2 1 ATOM 1808 N N . PHE A 1 237 ? 57.418 7.414 -13.867 1.00 36.85 ? 237 PHE A N 1 ATOM 1809 C CA . PHE A 1 237 ? 57.181 7.180 -15.276 1.00 35.07 ? 237 PHE A CA 1 ATOM 1810 C C . PHE A 1 237 ? 57.196 8.523 -15.987 1.00 34.06 ? 237 PHE A C 1 ATOM 1811 O O . PHE A 1 237 ? 56.386 9.393 -15.686 1.00 33.93 ? 237 PHE A O 1 ATOM 1812 C CB . PHE A 1 237 ? 55.832 6.501 -15.481 1.00 36.79 ? 237 PHE A CB 1 ATOM 1813 C CG . PHE A 1 237 ? 55.816 5.041 -15.117 1.00 39.13 ? 237 PHE A CG 1 ATOM 1814 C CD1 . PHE A 1 237 ? 55.934 4.064 -16.104 1.00 38.83 ? 237 PHE A CD1 1 ATOM 1815 C CD2 . PHE A 1 237 ? 55.668 4.635 -13.786 1.00 40.81 ? 237 PHE A CD2 1 ATOM 1816 C CE1 . PHE A 1 237 ? 55.915 2.713 -15.774 1.00 39.54 ? 237 PHE A CE1 1 ATOM 1817 C CE2 . PHE A 1 237 ? 55.652 3.279 -13.448 1.00 39.94 ? 237 PHE A CE2 1 ATOM 1818 C CZ . PHE A 1 237 ? 55.772 2.321 -14.444 1.00 39.89 ? 237 PHE A CZ 1 ATOM 1819 N N . LEU A 1 238 ? 58.129 8.689 -16.920 1.00 32.55 ? 238 LEU A N 1 ATOM 1820 C CA . LEU A 1 238 ? 58.246 9.915 -17.700 1.00 30.77 ? 238 LEU A CA 1 ATOM 1821 C C . LEU A 1 238 ? 57.757 9.663 -19.116 1.00 29.71 ? 238 LEU A C 1 ATOM 1822 O O . LEU A 1 238 ? 58.051 8.620 -19.689 1.00 31.57 ? 238 LEU A O 1 ATOM 1823 C CB . LEU A 1 238 ? 59.695 10.391 -17.715 1.00 31.26 ? 238 LEU A CB 1 ATOM 1824 C CG . LEU A 1 238 ? 60.404 10.381 -16.354 1.00 31.41 ? 238 LEU A CG 1 ATOM 1825 C CD1 . LEU A 1 238 ? 61.875 10.769 -16.511 1.00 31.46 ? 238 LEU A CD1 1 ATOM 1826 C CD2 . LEU A 1 238 ? 59.704 11.289 -15.340 1.00 30.61 ? 238 LEU A CD2 1 ATOM 1827 N N . PRO A 1 239 ? 56.987 10.604 -19.685 1.00 28.60 ? 239 PRO A N 1 ATOM 1828 C CA . PRO A 1 239 ? 56.444 10.343 -21.020 1.00 27.67 ? 239 PRO A CA 1 ATOM 1829 C C . PRO A 1 239 ? 57.435 10.631 -22.136 1.00 26.66 ? 239 PRO A C 1 ATOM 1830 O O . PRO A 1 239 ? 58.350 11.433 -21.968 1.00 26.13 ? 239 PRO A O 1 ATOM 1831 C CB . PRO A 1 239 ? 55.269 11.330 -21.119 1.00 26.58 ? 239 PRO A CB 1 ATOM 1832 C CG . PRO A 1 239 ? 55.678 12.470 -20.267 1.00 26.86 ? 239 PRO A CG 1 ATOM 1833 C CD . PRO A 1 239 ? 56.524 11.898 -19.144 1.00 27.89 ? 239 PRO A CD 1 ATOM 1834 N N . ASN A 1 240 ? 57.229 9.972 -23.266 1.00 26.46 ? 240 ASN A N 1 ATOM 1835 C CA . ASN A 1 240 ? 57.840 10.361 -24.515 1.00 27.08 ? 240 ASN A CA 1 ATOM 1836 C C . ASN A 1 240 ? 56.792 11.026 -25.394 1.00 28.70 ? 240 ASN A C 1 ATOM 1837 O O . ASN A 1 240 ? 55.585 10.796 -25.199 1.00 30.32 ? 240 ASN A O 1 ATOM 1838 C CB . ASN A 1 240 ? 58.415 9.137 -25.213 1.00 26.96 ? 240 ASN A CB 1 ATOM 1839 C CG . ASN A 1 240 ? 59.635 8.596 -24.514 1.00 27.86 ? 240 ASN A CG 1 ATOM 1840 O OD1 . ASN A 1 240 ? 60.457 9.350 -23.982 1.00 27.84 ? 240 ASN A OD1 1 ATOM 1841 N ND2 . ASN A 1 240 ? 59.768 7.277 -24.512 1.00 28.46 ? 240 ASN A ND2 1 ATOM 1842 N N . ALA A 1 241 ? 57.240 11.839 -26.357 1.00 28.90 ? 241 ALA A N 1 ATOM 1843 C CA . ALA A 1 241 ? 56.333 12.491 -27.321 1.00 29.00 ? 241 ALA A CA 1 ATOM 1844 C C . ALA A 1 241 ? 55.446 11.516 -28.108 1.00 29.86 ? 241 ALA A C 1 ATOM 1845 O O . ALA A 1 241 ? 54.254 11.756 -28.257 1.00 31.91 ? 241 ALA A O 1 ATOM 1846 C CB . ALA A 1 241 ? 57.106 13.383 -28.273 1.00 28.27 ? 241 ALA A CB 1 ATOM 1847 N N . ASP A 1 242 ? 56.022 10.412 -28.585 1.00 31.09 ? 242 ASP A N 1 ATOM 1848 C CA . ASP A 1 242 ? 55.321 9.455 -29.464 1.00 31.57 ? 242 ASP A CA 1 ATOM 1849 C C . ASP A 1 242 ? 54.355 8.521 -28.728 1.00 31.75 ? 242 ASP A C 1 ATOM 1850 O O . ASP A 1 242 ? 53.932 7.512 -29.272 1.00 32.37 ? 242 ASP A O 1 ATOM 1851 C CB . ASP A 1 242 ? 56.331 8.627 -30.271 1.00 31.53 ? 242 ASP A CB 1 ATOM 1852 C CG . ASP A 1 242 ? 57.224 7.748 -29.388 1.00 33.05 ? 242 ASP A CG 1 ATOM 1853 O OD1 . ASP A 1 242 ? 57.299 7.964 -28.151 1.00 31.84 ? 242 ASP A OD1 1 ATOM 1854 O OD2 . ASP A 1 242 ? 57.867 6.831 -29.946 1.00 34.27 ? 242 ASP A OD2 1 ATOM 1855 N N . GLU A 1 243 ? 54.016 8.864 -27.492 1.00 32.49 ? 243 GLU A N 1 ATOM 1856 C CA . GLU A 1 243 ? 52.998 8.147 -26.712 1.00 33.47 ? 243 GLU A CA 1 ATOM 1857 C C . GLU A 1 243 ? 53.490 6.784 -26.243 1.00 32.57 ? 243 GLU A C 1 ATOM 1858 O O . GLU A 1 243 ? 52.849 5.752 -26.439 1.00 33.39 ? 243 GLU A O 1 ATOM 1859 C CB . GLU A 1 243 ? 51.631 8.106 -27.429 1.00 33.67 ? 243 GLU A CB 1 ATOM 1860 C CG . GLU A 1 243 ? 51.029 9.514 -27.580 1.00 36.76 ? 243 GLU A CG 1 ATOM 1861 C CD . GLU A 1 243 ? 49.512 9.548 -27.639 1.00 38.77 ? 243 GLU A CD 1 ATOM 1862 O OE1 . GLU A 1 243 ? 48.887 10.293 -26.829 1.00 38.08 ? 243 GLU A OE1 1 ATOM 1863 O OE2 . GLU A 1 243 ? 48.953 8.831 -28.499 1.00 40.04 ? 243 GLU A OE2 1 ATOM 1864 N N . THR A 1 244 ? 54.663 6.814 -25.627 1.00 31.56 ? 244 THR A N 1 ATOM 1865 C CA . THR A 1 244 ? 55.269 5.664 -24.995 1.00 30.89 ? 244 THR A CA 1 ATOM 1866 C C . THR A 1 244 ? 55.900 6.218 -23.738 1.00 31.53 ? 244 THR A C 1 ATOM 1867 O O . THR A 1 244 ? 55.913 7.431 -23.529 1.00 31.58 ? 244 THR A O 1 ATOM 1868 C CB . THR A 1 244 ? 56.382 5.034 -25.853 1.00 29.67 ? 244 THR A CB 1 ATOM 1869 O OG1 . THR A 1 244 ? 57.436 5.986 -26.032 1.00 29.90 ? 244 THR A OG1 1 ATOM 1870 C CG2 . THR A 1 244 ? 55.867 4.563 -27.211 1.00 28.52 ? 244 THR A CG2 1 ATOM 1871 N N . TRP A 1 245 ? 56.438 5.330 -22.912 1.00 33.75 ? 245 TRP A N 1 ATOM 1872 C CA . TRP A 1 245 ? 56.959 5.719 -21.612 1.00 35.67 ? 245 TRP A CA 1 ATOM 1873 C C . TRP A 1 245 ? 58.447 5.581 -21.470 1.00 35.89 ? 245 TRP A C 1 ATOM 1874 O O . TRP A 1 245 ? 59.099 4.855 -22.228 1.00 37.20 ? 245 TRP A O 1 ATOM 1875 C CB . TRP A 1 245 ? 56.239 4.931 -20.528 1.00 36.62 ? 245 TRP A CB 1 ATOM 1876 C CG . TRP A 1 245 ? 54.790 5.320 -20.443 1.00 38.03 ? 245 TRP A CG 1 ATOM 1877 C CD1 . TRP A 1 245 ? 53.700 4.664 -20.998 1.00 36.86 ? 245 TRP A CD1 1 ATOM 1878 C CD2 . TRP A 1 245 ? 54.233 6.507 -19.788 1.00 39.18 ? 245 TRP A CD2 1 ATOM 1879 N NE1 . TRP A 1 245 ? 52.544 5.333 -20.723 1.00 38.03 ? 245 TRP A NE1 1 ATOM 1880 C CE2 . TRP A 1 245 ? 52.792 6.449 -20.000 1.00 39.04 ? 245 TRP A CE2 1 ATOM 1881 C CE3 . TRP A 1 245 ? 54.768 7.564 -19.052 1.00 39.74 ? 245 TRP A CE3 1 ATOM 1882 C CZ2 . TRP A 1 245 ? 51.937 7.419 -19.499 1.00 40.39 ? 245 TRP A CZ2 1 ATOM 1883 C CZ3 . TRP A 1 245 ? 53.899 8.539 -18.556 1.00 38.57 ? 245 TRP A CZ3 1 ATOM 1884 C CH2 . TRP A 1 245 ? 52.520 8.469 -18.777 1.00 39.71 ? 245 TRP A CH2 1 ATOM 1885 N N . TYR A 1 246 ? 58.984 6.290 -20.485 1.00 34.86 ? 246 TYR A N 1 ATOM 1886 C CA . TYR A 1 246 ? 60.375 6.180 -20.095 1.00 36.86 ? 246 TYR A CA 1 ATOM 1887 C C . TYR A 1 246 ? 60.426 6.013 -18.579 1.00 38.54 ? 246 TYR A C 1 ATOM 1888 O O . TYR A 1 246 ? 59.567 6.544 -17.866 1.00 37.74 ? 246 TYR A O 1 ATOM 1889 C CB . TYR A 1 246 ? 61.135 7.434 -20.545 1.00 37.13 ? 246 TYR A CB 1 ATOM 1890 C CG . TYR A 1 246 ? 62.568 7.592 -20.047 1.00 37.09 ? 246 TYR A CG 1 ATOM 1891 C CD1 . TYR A 1 246 ? 63.652 7.354 -20.895 1.00 37.05 ? 246 TYR A CD1 1 ATOM 1892 C CD2 . TYR A 1 246 ? 62.834 8.023 -18.745 1.00 36.67 ? 246 TYR A CD2 1 ATOM 1893 C CE1 . TYR A 1 246 ? 64.957 7.516 -20.453 1.00 37.37 ? 246 TYR A CE1 1 ATOM 1894 C CE2 . TYR A 1 246 ? 64.135 8.192 -18.296 1.00 37.38 ? 246 TYR A CE2 1 ATOM 1895 C CZ . TYR A 1 246 ? 65.194 7.943 -19.153 1.00 37.94 ? 246 TYR A CZ 1 ATOM 1896 O OH . TYR A 1 246 ? 66.489 8.122 -18.700 1.00 39.23 ? 246 TYR A OH 1 ATOM 1897 N N . LEU A 1 247 ? 61.436 5.279 -18.104 1.00 40.02 ? 247 LEU A N 1 ATOM 1898 C CA . LEU A 1 247 ? 61.627 4.966 -16.685 1.00 40.57 ? 247 LEU A CA 1 ATOM 1899 C C . LEU A 1 247 ? 63.057 4.489 -16.445 1.00 41.11 ? 247 LEU A C 1 ATOM 1900 O O . LEU A 1 247 ? 63.617 3.716 -17.245 1.00 38.94 ? 247 LEU A O 1 ATOM 1901 C CB . LEU A 1 247 ? 60.632 3.884 -16.231 1.00 40.96 ? 247 LEU A CB 1 ATOM 1902 C CG . LEU A 1 247 ? 60.846 3.110 -14.919 1.00 43.04 ? 247 LEU A CG 1 ATOM 1903 C CD1 . LEU A 1 247 ? 60.785 3.997 -13.687 1.00 43.08 ? 247 LEU A CD1 1 ATOM 1904 C CD2 . LEU A 1 247 ? 59.826 1.993 -14.786 1.00 44.04 ? 247 LEU A CD2 1 ATOM 1905 N N . GLN A 1 248 ? 63.640 4.959 -15.346 1.00 42.41 ? 248 GLN A N 1 ATOM 1906 C CA . GLN A 1 248 ? 64.951 4.493 -14.913 1.00 43.93 ? 248 GLN A CA 1 ATOM 1907 C C . GLN A 1 248 ? 64.951 3.928 -13.491 1.00 45.39 ? 248 GLN A C 1 ATOM 1908 O O . GLN A 1 248 ? 64.249 4.430 -12.606 1.00 45.56 ? 248 GLN A O 1 ATOM 1909 C CB . GLN A 1 248 ? 66.009 5.591 -15.071 1.00 44.39 ? 248 GLN A CB 1 ATOM 1910 C CG . GLN A 1 248 ? 65.956 6.731 -14.057 1.00 45.52 ? 248 GLN A CG 1 ATOM 1911 C CD . GLN A 1 248 ? 66.846 7.901 -14.466 1.00 47.22 ? 248 GLN A CD 1 ATOM 1912 O OE1 . GLN A 1 248 ? 66.965 8.232 -15.652 1.00 48.16 ? 248 GLN A OE1 1 ATOM 1913 N NE2 . GLN A 1 248 ? 67.478 8.528 -13.486 1.00 47.37 ? 248 GLN A NE2 1 ATOM 1914 N N . ALA A 1 249 ? 65.737 2.868 -13.298 1.00 45.95 ? 249 ALA A N 1 ATOM 1915 C CA . ALA A 1 249 ? 65.999 2.289 -11.978 1.00 43.98 ? 249 ALA A CA 1 ATOM 1916 C C . ALA A 1 249 ? 67.459 2.501 -11.596 1.00 44.95 ? 249 ALA A C 1 ATOM 1917 O O . ALA A 1 249 ? 68.366 2.133 -12.346 1.00 45.47 ? 249 ALA A O 1 ATOM 1918 C CB . ALA A 1 249 ? 65.672 0.821 -11.985 1.00 43.99 ? 249 ALA A CB 1 ATOM 1919 N N . THR A 1 250 ? 67.685 3.090 -10.427 1.00 48.37 ? 250 THR A N 1 ATOM 1920 C CA . THR A 1 250 ? 69.043 3.390 -9.958 1.00 51.10 ? 250 THR A CA 1 ATOM 1921 C C . THR A 1 250 ? 69.487 2.447 -8.846 1.00 52.43 ? 250 THR A C 1 ATOM 1922 O O . THR A 1 250 ? 68.713 2.168 -7.930 1.00 53.03 ? 250 THR A O 1 ATOM 1923 C CB . THR A 1 250 ? 69.130 4.817 -9.426 1.00 51.63 ? 250 THR A CB 1 ATOM 1924 O OG1 . THR A 1 250 ? 68.101 5.009 -8.450 1.00 53.26 ? 250 THR A OG1 1 ATOM 1925 C CG2 . THR A 1 250 ? 68.941 5.827 -10.555 1.00 51.73 ? 250 THR A CG2 1 ATOM 1926 N N . LEU A 1 251 ? 70.726 1.957 -8.931 1.00 55.10 ? 251 LEU A N 1 ATOM 1927 C CA . LEU A 1 251 ? 71.309 1.124 -7.863 1.00 56.82 ? 251 LEU A CA 1 ATOM 1928 C C . LEU A 1 251 ? 72.558 1.721 -7.228 1.00 58.37 ? 251 LEU A C 1 ATOM 1929 O O . LEU A 1 251 ? 73.525 2.050 -7.912 1.00 57.85 ? 251 LEU A O 1 ATOM 1930 C CB . LEU A 1 251 ? 71.612 -0.303 -8.346 1.00 55.68 ? 251 LEU A CB 1 ATOM 1931 C CG . LEU A 1 251 ? 72.053 -1.316 -7.269 1.00 55.04 ? 251 LEU A CG 1 ATOM 1932 C CD1 . LEU A 1 251 ? 71.049 -1.421 -6.131 1.00 54.01 ? 251 LEU A CD1 1 ATOM 1933 C CD2 . LEU A 1 251 ? 72.344 -2.700 -7.848 1.00 54.22 ? 251 LEU A CD2 1 ATOM 1934 N N . ASP A 1 252 ? 72.522 1.847 -5.908 1.00 63.66 ? 252 ASP A N 1 ATOM 1935 C CA . ASP A 1 252 ? 73.655 2.329 -5.133 1.00 67.55 ? 252 ASP A CA 1 ATOM 1936 C C . ASP A 1 252 ? 74.686 1.205 -4.986 1.00 69.24 ? 252 ASP A C 1 ATOM 1937 O O . ASP A 1 252 ? 74.329 0.091 -4.602 1.00 69.50 ? 252 ASP A O 1 ATOM 1938 C CB . ASP A 1 252 ? 73.153 2.799 -3.765 1.00 70.80 ? 252 ASP A CB 1 ATOM 1939 C CG . ASP A 1 252 ? 74.277 3.073 -2.782 1.00 74.62 ? 252 ASP A CG 1 ATOM 1940 O OD1 . ASP A 1 252 ? 75.292 3.686 -3.185 1.00 75.25 ? 252 ASP A OD1 1 ATOM 1941 O OD2 . ASP A 1 252 ? 74.135 2.682 -1.598 1.00 72.92 ? 252 ASP A OD2 1 ATOM 1942 N N . VAL A 1 253 ? 75.952 1.490 -5.311 1.00 71.31 ? 253 VAL A N 1 ATOM 1943 C CA . VAL A 1 253 ? 77.047 0.496 -5.188 1.00 72.99 ? 253 VAL A CA 1 ATOM 1944 C C . VAL A 1 253 ? 78.399 1.074 -4.702 1.00 74.88 ? 253 VAL A C 1 ATOM 1945 O O . VAL A 1 253 ? 78.651 2.279 -4.800 1.00 76.51 ? 253 VAL A O 1 ATOM 1946 C CB . VAL A 1 253 ? 77.293 -0.324 -6.511 1.00 68.74 ? 253 VAL A CB 1 ATOM 1947 C CG1 . VAL A 1 253 ? 76.044 -1.071 -6.955 1.00 66.79 ? 253 VAL A CG1 1 ATOM 1948 C CG2 . VAL A 1 253 ? 77.821 0.562 -7.627 1.00 69.45 ? 253 VAL A CG2 1 ATOM 1949 N N . GLU A 1 254 ? 79.259 0.202 -4.176 1.00 75.35 ? 254 GLU A N 1 ATOM 1950 C CA . GLU A 1 254 ? 80.648 0.559 -3.895 1.00 72.48 ? 254 GLU A CA 1 ATOM 1951 C C . GLU A 1 254 ? 81.489 0.296 -5.151 1.00 72.14 ? 254 GLU A C 1 ATOM 1952 O O . GLU A 1 254 ? 81.448 -0.799 -5.721 1.00 67.83 ? 254 GLU A O 1 ATOM 1953 C CB . GLU A 1 254 ? 81.182 -0.218 -2.687 1.00 68.88 ? 254 GLU A CB 1 ATOM 1954 N N . ALA A 1 255 ? 82.229 1.313 -5.590 1.00 74.75 ? 255 ALA A N 1 ATOM 1955 C CA . ALA A 1 255 ? 83.030 1.225 -6.815 1.00 75.53 ? 255 ALA A CA 1 ATOM 1956 C C . ALA A 1 255 ? 83.905 -0.035 -6.824 1.00 76.86 ? 255 ALA A C 1 ATOM 1957 O O . ALA A 1 255 ? 84.461 -0.421 -5.793 1.00 75.43 ? 255 ALA A O 1 ATOM 1958 C CB . ALA A 1 255 ? 83.876 2.492 -7.003 1.00 68.15 ? 255 ALA A CB 1 ATOM 1959 N N . GLY A 1 256 ? 83.999 -0.680 -7.985 1.00 77.81 ? 256 GLY A N 1 ATOM 1960 C CA . GLY A 1 256 ? 84.765 -1.915 -8.122 1.00 78.67 ? 256 GLY A CA 1 ATOM 1961 C C . GLY A 1 256 ? 83.902 -3.158 -8.253 1.00 82.45 ? 256 GLY A C 1 ATOM 1962 O O . GLY A 1 256 ? 84.287 -4.110 -8.939 1.00 83.57 ? 256 GLY A O 1 ATOM 1963 N N . GLU A 1 257 ? 82.735 -3.151 -7.604 1.00 81.95 ? 257 GLU A N 1 ATOM 1964 C CA . GLU A 1 257 ? 81.836 -4.316 -7.604 1.00 79.04 ? 257 GLU A CA 1 ATOM 1965 C C . GLU A 1 257 ? 80.722 -4.276 -8.671 1.00 77.69 ? 257 GLU A C 1 ATOM 1966 O O . GLU A 1 257 ? 79.697 -4.955 -8.540 1.00 74.00 ? 257 GLU A O 1 ATOM 1967 C CB . GLU A 1 257 ? 81.255 -4.551 -6.204 1.00 77.11 ? 257 GLU A CB 1 ATOM 1968 C CG . GLU A 1 257 ? 80.294 -3.479 -5.709 1.00 76.00 ? 257 GLU A CG 1 ATOM 1969 C CD . GLU A 1 257 ? 79.907 -3.667 -4.249 1.00 77.01 ? 257 GLU A CD 1 ATOM 1970 O OE1 . GLU A 1 257 ? 78.834 -3.167 -3.842 1.00 73.90 ? 257 GLU A OE1 1 ATOM 1971 O OE2 . GLU A 1 257 ? 80.677 -4.314 -3.506 1.00 76.20 ? 257 GLU A OE2 1 ATOM 1972 N N . GLU A 1 258 ? 80.943 -3.495 -9.729 1.00 77.98 ? 258 GLU A N 1 ATOM 1973 C CA . GLU A 1 258 ? 79.984 -3.360 -10.828 1.00 73.67 ? 258 GLU A CA 1 ATOM 1974 C C . GLU A 1 258 ? 79.873 -4.637 -11.651 1.00 72.08 ? 258 GLU A C 1 ATOM 1975 O O . GLU A 1 258 ? 78.770 -5.125 -11.894 1.00 74.64 ? 258 GLU A O 1 ATOM 1976 C CB . GLU A 1 258 ? 80.340 -2.180 -11.739 1.00 72.34 ? 258 GLU A CB 1 ATOM 1977 C CG . GLU A 1 258 ? 80.189 -0.809 -11.088 1.00 72.36 ? 258 GLU A CG 1 ATOM 1978 C CD . GLU A 1 258 ? 81.495 -0.253 -10.535 1.00 70.76 ? 258 GLU A CD 1 ATOM 1979 O OE1 . GLU A 1 258 ? 82.472 -1.024 -10.398 1.00 70.43 ? 258 GLU A OE1 1 ATOM 1980 O OE2 . GLU A 1 258 ? 81.541 0.967 -10.244 1.00 68.40 ? 258 GLU A OE2 1 ATOM 1981 N N . ALA A 1 259 ? 81.014 -5.166 -12.083 1.00 71.71 ? 259 ALA A N 1 ATOM 1982 C CA . ALA A 1 259 ? 81.053 -6.435 -12.803 1.00 70.93 ? 259 ALA A CA 1 ATOM 1983 C C . ALA A 1 259 ? 80.210 -7.435 -12.026 1.00 71.05 ? 259 ALA A C 1 ATOM 1984 O O . ALA A 1 259 ? 80.267 -7.477 -10.792 1.00 67.31 ? 259 ALA A O 1 ATOM 1985 N N . GLY A 1 260 ? 79.404 -8.209 -12.747 1.00 73.19 ? 260 GLY A N 1 ATOM 1986 C CA . GLY A 1 260 ? 78.488 -9.159 -12.120 1.00 73.49 ? 260 GLY A CA 1 ATOM 1987 C C . GLY A 1 260 ? 77.028 -8.736 -12.145 1.00 73.00 ? 260 GLY A C 1 ATOM 1988 O O . GLY A 1 260 ? 76.135 -9.584 -12.226 1.00 75.02 ? 260 GLY A O 1 ATOM 1989 N N . LEU A 1 261 ? 76.785 -7.429 -12.065 1.00 70.39 ? 261 LEU A N 1 ATOM 1990 C CA . LEU A 1 261 ? 75.424 -6.894 -12.061 1.00 67.92 ? 261 LEU A CA 1 ATOM 1991 C C . LEU A 1 261 ? 74.824 -6.847 -13.467 1.00 69.29 ? 261 LEU A C 1 ATOM 1992 O O . LEU A 1 261 ? 75.529 -6.597 -14.456 1.00 69.93 ? 261 LEU A O 1 ATOM 1993 C CB . LEU A 1 261 ? 75.377 -5.514 -11.396 1.00 64.75 ? 261 LEU A CB 1 ATOM 1994 C CG . LEU A 1 261 ? 75.529 -5.444 -9.869 1.00 64.29 ? 261 LEU A CG 1 ATOM 1995 C CD1 . LEU A 1 261 ? 75.663 -4.005 -9.386 1.00 62.96 ? 261 LEU A CD1 1 ATOM 1996 C CD2 . LEU A 1 261 ? 74.363 -6.112 -9.166 1.00 66.80 ? 261 LEU A CD2 1 ATOM 1997 N N . ALA A 1 262 ? 73.519 -7.109 -13.540 1.00 68.33 ? 262 ALA A N 1 ATOM 1998 C CA . ALA A 1 262 ? 72.771 -7.116 -14.802 1.00 65.52 ? 262 ALA A CA 1 ATOM 1999 C C . ALA A 1 262 ? 71.422 -6.424 -14.627 1.00 62.13 ? 262 ALA A C 1 ATOM 2000 O O . ALA A 1 262 ? 70.959 -6.240 -13.500 1.00 62.30 ? 262 ALA A O 1 ATOM 2001 C CB . ALA A 1 262 ? 72.571 -8.539 -15.293 1.00 66.14 ? 262 ALA A CB 1 ATOM 2002 N N . CYS A 1 263 ? 70.799 -6.035 -15.737 1.00 58.32 ? 263 CYS A N 1 ATOM 2003 C CA . CYS A 1 263 ? 69.480 -5.415 -15.683 1.00 55.13 ? 263 CYS A CA 1 ATOM 2004 C C . CYS A 1 263 ? 68.436 -6.260 -16.399 1.00 54.24 ? 263 CYS A C 1 ATOM 2005 O O . CYS A 1 263 ? 68.539 -6.501 -17.608 1.00 53.93 ? 263 CYS A O 1 ATOM 2006 C CB . CYS A 1 263 ? 69.510 -4.004 -16.263 1.00 55.86 ? 263 CYS A CB 1 ATOM 2007 S SG . CYS A 1 263 ? 68.150 -2.994 -15.668 1.00 59.84 ? 263 CYS A SG 1 ATOM 2008 N N . ARG A 1 264 ? 67.445 -6.727 -15.641 1.00 52.68 ? 264 ARG A N 1 ATOM 2009 C CA . ARG A 1 264 ? 66.335 -7.481 -16.217 1.00 51.15 ? 264 ARG A CA 1 ATOM 2010 C C . ARG A 1 264 ? 65.098 -6.589 -16.315 1.00 48.53 ? 264 ARG A C 1 ATOM 2011 O O . ARG A 1 264 ? 64.753 -5.848 -15.367 1.00 46.33 ? 264 ARG A O 1 ATOM 2012 C CB . ARG A 1 264 ? 66.043 -8.749 -15.408 1.00 54.93 ? 264 ARG A CB 1 ATOM 2013 C CG . ARG A 1 264 ? 65.290 -9.853 -16.176 1.00 58.35 ? 264 ARG A CG 1 ATOM 2014 C CD . ARG A 1 264 ? 65.405 -11.235 -15.477 1.00 61.02 ? 264 ARG A CD 1 ATOM 2015 N NE . ARG A 1 264 ? 64.687 -12.304 -16.183 1.00 60.83 ? 264 ARG A NE 1 ATOM 2016 C CZ . ARG A 1 264 ? 65.166 -12.995 -17.221 1.00 61.93 ? 264 ARG A CZ 1 ATOM 2017 N NH1 . ARG A 1 264 ? 66.379 -12.744 -17.706 1.00 64.32 ? 264 ARG A NH1 1 ATOM 2018 N NH2 . ARG A 1 264 ? 64.422 -13.937 -17.791 1.00 59.02 ? 264 ARG A NH2 1 ATOM 2019 N N . VAL A 1 265 ? 64.449 -6.663 -17.477 1.00 42.62 ? 265 VAL A N 1 ATOM 2020 C CA . VAL A 1 265 ? 63.288 -5.838 -17.792 1.00 39.45 ? 265 VAL A CA 1 ATOM 2021 C C . VAL A 1 265 ? 62.183 -6.723 -18.359 1.00 38.04 ? 265 VAL A C 1 ATOM 2022 O O . VAL A 1 265 ? 62.375 -7.372 -19.399 1.00 35.70 ? 265 VAL A O 1 ATOM 2023 C CB . VAL A 1 265 ? 63.677 -4.690 -18.781 1.00 39.08 ? 265 VAL A CB 1 ATOM 2024 C CG1 . VAL A 1 265 ? 62.475 -4.139 -19.532 1.00 38.16 ? 265 VAL A CG1 1 ATOM 2025 C CG2 . VAL A 1 265 ? 64.389 -3.577 -18.037 1.00 39.38 ? 265 VAL A CG2 1 ATOM 2026 N N . LYS A 1 266 ? 61.048 -6.764 -17.652 1.00 36.80 ? 266 LYS A N 1 ATOM 2027 C CA . LYS A 1 266 ? 59.854 -7.498 -18.102 1.00 36.69 ? 266 LYS A CA 1 ATOM 2028 C C . LYS A 1 266 ? 58.800 -6.519 -18.577 1.00 34.19 ? 266 LYS A C 1 ATOM 2029 O O . LYS A 1 266 ? 58.551 -5.493 -17.921 1.00 33.94 ? 266 LYS A O 1 ATOM 2030 C CB . LYS A 1 266 ? 59.241 -8.338 -16.975 1.00 40.43 ? 266 LYS A CB 1 ATOM 2031 C CG . LYS A 1 266 ? 60.155 -9.364 -16.336 1.00 44.95 ? 266 LYS A CG 1 ATOM 2032 C CD . LYS A 1 266 ? 59.578 -9.892 -15.014 1.00 46.17 ? 266 LYS A CD 1 ATOM 2033 C CE . LYS A 1 266 ? 60.519 -10.920 -14.380 1.00 48.68 ? 266 LYS A CE 1 ATOM 2034 N NZ . LYS A 1 266 ? 60.674 -12.170 -15.208 1.00 49.63 ? 266 LYS A NZ 1 ATOM 2035 N N . HIS A 1 267 ? 58.161 -6.853 -19.696 1.00 31.17 ? 267 HIS A N 1 ATOM 2036 C CA . HIS A 1 267 ? 57.097 -6.032 -20.262 1.00 30.59 ? 267 HIS A CA 1 ATOM 2037 C C . HIS A 1 267 ? 56.272 -6.817 -21.248 1.00 30.24 ? 267 HIS A C 1 ATOM 2038 O O . HIS A 1 267 ? 56.800 -7.583 -22.044 1.00 31.17 ? 267 HIS A O 1 ATOM 2039 C CB . HIS A 1 267 ? 57.676 -4.767 -20.921 1.00 30.71 ? 267 HIS A CB 1 ATOM 2040 C CG . HIS A 1 267 ? 56.628 -3.870 -21.532 1.00 29.91 ? 267 HIS A CG 1 ATOM 2041 N ND1 . HIS A 1 267 ? 56.152 -4.059 -22.772 1.00 29.91 ? 267 HIS A ND1 1 ATOM 2042 C CD2 . HIS A 1 267 ? 55.933 -2.786 -21.007 1.00 29.73 ? 267 HIS A CD2 1 ATOM 2043 C CE1 . HIS A 1 267 ? 55.201 -3.147 -23.032 1.00 30.20 ? 267 HIS A CE1 1 ATOM 2044 N NE2 . HIS A 1 267 ? 55.074 -2.363 -21.953 1.00 30.38 ? 267 HIS A NE2 1 ATOM 2045 N N . SER A 1 268 ? 54.966 -6.601 -21.232 1.00 31.08 ? 268 SER A N 1 ATOM 2046 C CA . SER A 1 268 ? 54.043 -7.377 -22.061 1.00 32.89 ? 268 SER A CA 1 ATOM 2047 C C . SER A 1 268 ? 54.387 -7.453 -23.558 1.00 33.65 ? 268 SER A C 1 ATOM 2048 O O . SER A 1 268 ? 53.999 -8.402 -24.238 1.00 34.07 ? 268 SER A O 1 ATOM 2049 C CB . SER A 1 268 ? 52.610 -6.874 -21.866 1.00 33.61 ? 268 SER A CB 1 ATOM 2050 O OG . SER A 1 268 ? 52.528 -5.472 -22.065 1.00 35.57 ? 268 SER A OG 1 ATOM 2051 N N . SER A 1 269 ? 55.102 -6.457 -24.071 1.00 34.77 ? 269 SER A N 1 ATOM 2052 C CA . SER A 1 269 ? 55.406 -6.388 -25.510 1.00 36.45 ? 269 SER A CA 1 ATOM 2053 C C . SER A 1 269 ? 56.484 -7.384 -25.927 1.00 37.18 ? 269 SER A C 1 ATOM 2054 O O . SER A 1 269 ? 56.583 -7.757 -27.101 1.00 34.42 ? 269 SER A O 1 ATOM 2055 C CB . SER A 1 269 ? 55.852 -4.981 -25.894 1.00 35.47 ? 269 SER A CB 1 ATOM 2056 O OG . SER A 1 269 ? 57.005 -4.605 -25.158 1.00 34.47 ? 269 SER A OG 1 ATOM 2057 N N . LEU A 1 270 ? 57.278 -7.803 -24.942 1.00 39.34 ? 270 LEU A N 1 ATOM 2058 C CA . LEU A 1 270 ? 58.442 -8.648 -25.161 1.00 42.69 ? 270 LEU A CA 1 ATOM 2059 C C . LEU A 1 270 ? 58.052 -10.104 -25.370 1.00 48.03 ? 270 LEU A C 1 ATOM 2060 O O . LEU A 1 270 ? 58.866 -10.906 -25.848 1.00 49.96 ? 270 LEU A O 1 ATOM 2061 C CB . LEU A 1 270 ? 59.431 -8.518 -23.993 1.00 40.39 ? 270 LEU A CB 1 ATOM 2062 C CG . LEU A 1 270 ? 60.083 -7.149 -23.739 1.00 39.67 ? 270 LEU A CG 1 ATOM 2063 C CD1 . LEU A 1 270 ? 61.072 -7.220 -22.584 1.00 39.03 ? 270 LEU A CD1 1 ATOM 2064 C CD2 . LEU A 1 270 ? 60.765 -6.594 -25.000 1.00 37.81 ? 270 LEU A CD2 1 ATOM 2065 N N . GLY A 1 271 ? 56.808 -10.435 -25.014 1.00 52.47 ? 271 GLY A N 1 ATOM 2066 C CA . GLY A 1 271 ? 56.266 -11.785 -25.179 1.00 53.90 ? 271 GLY A CA 1 ATOM 2067 C C . GLY A 1 271 ? 57.129 -12.807 -24.471 1.00 57.92 ? 271 GLY A C 1 ATOM 2068 O O . GLY A 1 271 ? 57.578 -13.781 -25.088 1.00 59.55 ? 271 GLY A O 1 ATOM 2069 N N . GLY A 1 272 ? 57.397 -12.550 -23.188 1.00 56.82 ? 272 GLY A N 1 ATOM 2070 C CA . GLY A 1 272 ? 58.159 -13.460 -22.336 1.00 58.73 ? 272 GLY A CA 1 ATOM 2071 C C . GLY A 1 272 ? 59.658 -13.548 -22.567 1.00 61.10 ? 272 GLY A C 1 ATOM 2072 O O . GLY A 1 272 ? 60.338 -14.339 -21.917 1.00 64.69 ? 272 GLY A O 1 ATOM 2073 N N . GLN A 1 273 ? 60.172 -12.741 -23.491 1.00 63.40 ? 273 GLN A N 1 ATOM 2074 C CA . GLN A 1 273 ? 61.605 -12.693 -23.787 1.00 60.34 ? 273 GLN A CA 1 ATOM 2075 C C . GLN A 1 273 ? 62.243 -11.496 -23.088 1.00 57.51 ? 273 GLN A C 1 ATOM 2076 O O . GLN A 1 273 ? 62.648 -10.524 -23.734 1.00 58.45 ? 273 GLN A O 1 ATOM 2077 C CB . GLN A 1 273 ? 61.850 -12.637 -25.305 1.00 62.50 ? 273 GLN A CB 1 ATOM 2078 C CG . GLN A 1 273 ? 61.498 -13.924 -26.064 1.00 65.87 ? 273 GLN A CG 1 ATOM 2079 C CD . GLN A 1 273 ? 62.589 -15.005 -26.001 1.00 67.27 ? 273 GLN A CD 1 ATOM 2080 O OE1 . GLN A 1 273 ? 62.616 -15.905 -26.839 1.00 67.76 ? 273 GLN A OE1 1 ATOM 2081 N NE2 . GLN A 1 273 ? 63.487 -14.914 -25.020 1.00 65.48 ? 273 GLN A NE2 1 ATOM 2082 N N . ASP A 1 274 ? 62.321 -11.576 -21.763 1.00 54.98 ? 274 ASP A N 1 ATOM 2083 C CA . ASP A 1 274 ? 62.889 -10.515 -20.934 1.00 56.02 ? 274 ASP A CA 1 ATOM 2084 C C . ASP A 1 274 ? 64.192 -9.968 -21.518 1.00 57.74 ? 274 ASP A C 1 ATOM 2085 O O . ASP A 1 274 ? 64.967 -10.706 -22.125 1.00 59.03 ? 274 ASP A O 1 ATOM 2086 C CB . ASP A 1 274 ? 63.111 -11.016 -19.504 1.00 55.42 ? 274 ASP A CB 1 ATOM 2087 C CG . ASP A 1 274 ? 61.836 -11.573 -18.869 1.00 60.02 ? 274 ASP A CG 1 ATOM 2088 O OD1 . ASP A 1 274 ? 60.932 -12.005 -19.618 1.00 66.12 ? 274 ASP A OD1 1 ATOM 2089 O OD2 . ASP A 1 274 ? 61.730 -11.592 -17.622 1.00 56.90 ? 274 ASP A OD2 1 ATOM 2090 N N . ILE A 1 275 ? 64.409 -8.666 -21.364 1.00 59.08 ? 275 ILE A N 1 ATOM 2091 C CA . ILE A 1 275 ? 65.653 -8.049 -21.803 1.00 58.09 ? 275 ILE A CA 1 ATOM 2092 C C . ILE A 1 275 ? 66.639 -8.123 -20.655 1.00 57.76 ? 275 ILE A C 1 ATOM 2093 O O . ILE A 1 275 ? 66.347 -7.715 -19.528 1.00 56.00 ? 275 ILE A O 1 ATOM 2094 C CB . ILE A 1 275 ? 65.471 -6.576 -22.290 1.00 58.11 ? 275 ILE A CB 1 ATOM 2095 C CG1 . ILE A 1 275 ? 64.705 -6.535 -23.624 1.00 56.11 ? 275 ILE A CG1 1 ATOM 2096 C CG2 . ILE A 1 275 ? 66.824 -5.886 -22.426 1.00 57.17 ? 275 ILE A CG2 1 ATOM 2097 C CD1 . ILE A 1 275 ? 64.695 -5.174 -24.330 1.00 53.80 ? 275 ILE A CD1 1 ATOM 2098 N N . ILE A 1 276 ? 67.806 -8.670 -20.957 1.00 60.97 ? 276 ILE A N 1 ATOM 2099 C CA . ILE A 1 276 ? 68.864 -8.806 -19.972 1.00 62.86 ? 276 ILE A CA 1 ATOM 2100 C C . ILE A 1 276 ? 70.113 -8.033 -20.423 1.00 60.35 ? 276 ILE A C 1 ATOM 2101 O O . ILE A 1 276 ? 70.531 -8.103 -21.586 1.00 57.69 ? 276 ILE A O 1 ATOM 2102 C CB . ILE A 1 276 ? 69.138 -10.316 -19.643 1.00 67.97 ? 276 ILE A CB 1 ATOM 2103 C CG1 . ILE A 1 276 ? 69.823 -10.469 -18.277 1.00 68.36 ? 276 ILE A CG1 1 ATOM 2104 C CG2 . ILE A 1 276 ? 69.879 -11.055 -20.804 1.00 69.05 ? 276 ILE A CG2 1 ATOM 2105 C CD1 . ILE A 1 276 ? 68.862 -10.485 -17.099 1.00 65.22 ? 276 ILE A CD1 1 ATOM 2106 N N . LEU A 1 277 ? 70.686 -7.267 -19.506 1.00 60.68 ? 277 LEU A N 1 ATOM 2107 C CA . LEU A 1 277 ? 71.771 -6.362 -19.869 1.00 62.49 ? 277 LEU A CA 1 ATOM 2108 C C . LEU A 1 277 ? 72.853 -6.368 -18.803 1.00 62.91 ? 277 LEU A C 1 ATOM 2109 O O . LEU A 1 277 ? 72.706 -5.726 -17.758 1.00 62.32 ? 277 LEU A O 1 ATOM 2110 C CB . LEU A 1 277 ? 71.225 -4.945 -20.075 1.00 60.23 ? 277 LEU A CB 1 ATOM 2111 C CG . LEU A 1 277 ? 71.670 -4.160 -21.306 1.00 59.87 ? 277 LEU A CG 1 ATOM 2112 C CD1 . LEU A 1 277 ? 71.166 -4.813 -22.588 1.00 60.06 ? 277 LEU A CD1 1 ATOM 2113 C CD2 . LEU A 1 277 ? 71.159 -2.742 -21.211 1.00 60.07 ? 277 LEU A CD2 1 ATOM 2114 N N . TYR A 1 278 ? 73.929 -7.107 -19.067 1.00 61.89 ? 278 TYR A N 1 ATOM 2115 C CA . TYR A 1 278 ? 75.035 -7.224 -18.122 1.00 63.88 ? 278 TYR A CA 1 ATOM 2116 C C . TYR A 1 278 ? 75.951 -6.011 -18.227 1.00 65.69 ? 278 TYR A C 1 ATOM 2117 O O . TYR A 1 278 ? 76.099 -5.432 -19.306 1.00 67.09 ? 278 TYR A O 1 ATOM 2118 C CB . TYR A 1 278 ? 75.838 -8.497 -18.387 1.00 62.45 ? 278 TYR A CB 1 ATOM 2119 C CG . TYR A 1 278 ? 75.029 -9.763 -18.303 1.00 63.68 ? 278 TYR A CG 1 ATOM 2120 C CD1 . TYR A 1 278 ? 74.469 -10.332 -19.452 1.00 65.00 ? 278 TYR A CD1 1 ATOM 2121 C CD2 . TYR A 1 278 ? 74.825 -10.403 -17.074 1.00 63.52 ? 278 TYR A CD2 1 ATOM 2122 C CE1 . TYR A 1 278 ? 73.715 -11.505 -19.381 1.00 66.20 ? 278 TYR A CE1 1 ATOM 2123 C CE2 . TYR A 1 278 ? 74.071 -11.575 -16.986 1.00 63.97 ? 278 TYR A CE2 1 ATOM 2124 C CZ . TYR A 1 278 ? 73.520 -12.119 -18.144 1.00 67.32 ? 278 TYR A CZ 1 ATOM 2125 O OH . TYR A 1 278 ? 72.772 -13.272 -18.070 1.00 68.74 ? 278 TYR A OH 1 ATOM 2126 N N . TRP A 1 279 ? 76.559 -5.629 -17.106 1.00 65.83 ? 279 TRP A N 1 ATOM 2127 C CA . TRP A 1 279 ? 77.564 -4.576 -17.103 1.00 66.06 ? 279 TRP A CA 1 ATOM 2128 C C . TRP A 1 279 ? 78.950 -5.136 -17.223 1.00 63.28 ? 279 TRP A C 1 ATOM 2129 O O . TRP A 1 279 ? 79.528 -5.146 -18.305 1.00 59.09 ? 279 TRP A O 1 ATOM 2130 C CB . TRP A 1 279 ? 77.453 -3.724 -15.850 1.00 73.00 ? 279 TRP A CB 1 ATOM 2131 C CG . TRP A 1 279 ? 78.245 -2.442 -15.934 1.00 78.53 ? 279 TRP A CG 1 ATOM 2132 C CD1 . TRP A 1 279 ? 79.032 -1.865 -14.942 1.00 76.53 ? 279 TRP A CD1 1 ATOM 2133 C CD2 . TRP A 1 279 ? 78.359 -1.533 -17.094 1.00 85.25 ? 279 TRP A CD2 1 ATOM 2134 N NE1 . TRP A 1 279 ? 79.597 -0.698 -15.384 1.00 83.12 ? 279 TRP A NE1 1 ATOM 2135 C CE2 . TRP A 1 279 ? 79.237 -0.439 -16.667 1.00 88.29 ? 279 TRP A CE2 1 ATOM 2136 C CE3 . TRP A 1 279 ? 77.837 -1.517 -18.397 1.00 86.72 ? 279 TRP A CE3 1 ATOM 2137 C CZ2 . TRP A 1 279 ? 79.569 0.616 -17.522 1.00 90.17 ? 279 TRP A CZ2 1 ATOM 2138 C CZ3 . TRP A 1 279 ? 78.179 -0.450 -19.247 1.00 84.33 ? 279 TRP A CZ3 1 ATOM 2139 C CH2 . TRP A 1 279 ? 79.022 0.589 -18.819 1.00 86.48 ? 279 TRP A CH2 1 ATOM 2140 N N . GLN B 2 2 ? 52.032 28.210 -4.063 1.00 64.60 ? 2 GLN B N 1 ATOM 2141 C CA . GLN B 2 2 ? 52.740 27.897 -5.342 1.00 67.28 ? 2 GLN B CA 1 ATOM 2142 C C . GLN B 2 2 ? 53.556 26.597 -5.274 1.00 67.16 ? 2 GLN B C 1 ATOM 2143 O O . GLN B 2 2 ? 54.004 26.176 -4.202 1.00 66.72 ? 2 GLN B O 1 ATOM 2144 C CB . GLN B 2 2 ? 53.639 29.071 -5.762 1.00 68.50 ? 2 GLN B CB 1 ATOM 2145 C CG . GLN B 2 2 ? 52.866 30.334 -6.145 1.00 74.17 ? 2 GLN B CG 1 ATOM 2146 C CD . GLN B 2 2 ? 53.757 31.482 -6.613 1.00 76.29 ? 2 GLN B CD 1 ATOM 2147 O OE1 . GLN B 2 2 ? 54.676 31.901 -5.908 1.00 75.15 ? 2 GLN B OE1 1 ATOM 2148 N NE2 . GLN B 2 2 ? 53.467 32.010 -7.800 1.00 75.84 ? 2 GLN B NE2 1 ATOM 2149 N N . LYS B 2 3 ? 53.727 25.962 -6.430 1.00 64.97 ? 3 LYS B N 1 ATOM 2150 C CA . LYS B 2 3 ? 54.647 24.840 -6.570 1.00 60.76 ? 3 LYS B CA 1 ATOM 2151 C C . LYS B 2 3 ? 55.824 25.291 -7.443 1.00 58.82 ? 3 LYS B C 1 ATOM 2152 O O . LYS B 2 3 ? 55.626 25.978 -8.452 1.00 56.18 ? 3 LYS B O 1 ATOM 2153 N N . THR B 2 4 ? 57.042 24.929 -7.035 1.00 56.61 ? 4 THR B N 1 ATOM 2154 C CA . THR B 2 4 ? 58.243 25.176 -7.843 1.00 55.44 ? 4 THR B CA 1 ATOM 2155 C C . THR B 2 4 ? 58.471 24.014 -8.824 1.00 53.63 ? 4 THR B C 1 ATOM 2156 O O . THR B 2 4 ? 58.449 22.852 -8.411 1.00 57.13 ? 4 THR B O 1 ATOM 2157 C CB . THR B 2 4 ? 59.507 25.368 -6.975 1.00 55.60 ? 4 THR B CB 1 ATOM 2158 O OG1 . THR B 2 4 ? 59.630 24.268 -6.064 1.00 56.12 ? 4 THR B OG1 1 ATOM 2159 C CG2 . THR B 2 4 ? 59.443 26.681 -6.199 1.00 54.55 ? 4 THR B CG2 1 ATOM 2160 N N . PRO B 2 5 ? 58.705 24.326 -10.117 1.00 48.03 ? 5 PRO B N 1 ATOM 2161 C CA . PRO B 2 5 ? 58.760 23.328 -11.179 1.00 45.22 ? 5 PRO B CA 1 ATOM 2162 C C . PRO B 2 5 ? 59.785 22.235 -10.929 1.00 44.55 ? 5 PRO B C 1 ATOM 2163 O O . PRO B 2 5 ? 60.882 22.518 -10.457 1.00 44.83 ? 5 PRO B O 1 ATOM 2164 C CB . PRO B 2 5 ? 59.198 24.140 -12.401 1.00 45.38 ? 5 PRO B CB 1 ATOM 2165 C CG . PRO B 2 5 ? 58.892 25.528 -12.086 1.00 45.37 ? 5 PRO B CG 1 ATOM 2166 C CD . PRO B 2 5 ? 59.052 25.665 -10.621 1.00 47.97 ? 5 PRO B CD 1 ATOM 2167 N N . GLN B 2 6 ? 59.412 20.995 -11.224 1.00 43.47 ? 6 GLN B N 1 ATOM 2168 C CA . GLN B 2 6 ? 60.376 19.916 -11.332 1.00 42.86 ? 6 GLN B CA 1 ATOM 2169 C C . GLN B 2 6 ? 60.722 19.785 -12.802 1.00 40.91 ? 6 GLN B C 1 ATOM 2170 O O . GLN B 2 6 ? 59.828 19.741 -13.653 1.00 40.33 ? 6 GLN B O 1 ATOM 2171 C CB . GLN B 2 6 ? 59.809 18.597 -10.806 1.00 45.57 ? 6 GLN B CB 1 ATOM 2172 C CG . GLN B 2 6 ? 59.696 18.515 -9.281 1.00 52.41 ? 6 GLN B CG 1 ATOM 2173 C CD . GLN B 2 6 ? 61.034 18.643 -8.561 1.00 54.46 ? 6 GLN B CD 1 ATOM 2174 O OE1 . GLN B 2 6 ? 62.049 18.095 -9.001 1.00 57.09 ? 6 GLN B OE1 1 ATOM 2175 N NE2 . GLN B 2 6 ? 61.036 19.364 -7.442 1.00 54.24 ? 6 GLN B NE2 1 ATOM 2176 N N . ILE B 2 7 ? 62.017 19.749 -13.101 1.00 37.87 ? 7 ILE B N 1 ATOM 2177 C CA . ILE B 2 7 ? 62.482 19.621 -14.482 1.00 35.13 ? 7 ILE B CA 1 ATOM 2178 C C . ILE B 2 7 ? 63.241 18.316 -14.612 1.00 33.54 ? 7 ILE B C 1 ATOM 2179 O O . ILE B 2 7 ? 64.029 17.978 -13.739 1.00 34.81 ? 7 ILE B O 1 ATOM 2180 C CB . ILE B 2 7 ? 63.396 20.796 -14.895 1.00 34.36 ? 7 ILE B CB 1 ATOM 2181 C CG1 . ILE B 2 7 ? 62.767 22.145 -14.522 1.00 34.77 ? 7 ILE B CG1 1 ATOM 2182 C CG2 . ILE B 2 7 ? 63.689 20.750 -16.381 1.00 34.03 ? 7 ILE B CG2 1 ATOM 2183 C CD1 . ILE B 2 7 ? 63.733 23.310 -14.593 1.00 34.67 ? 7 ILE B CD1 1 ATOM 2184 N N . GLN B 2 8 ? 62.991 17.573 -15.687 1.00 32.16 ? 8 GLN B N 1 ATOM 2185 C CA . GLN B 2 8 ? 63.699 16.319 -15.922 1.00 31.46 ? 8 GLN B CA 1 ATOM 2186 C C . GLN B 2 8 ? 64.051 16.138 -17.391 1.00 30.08 ? 8 GLN B C 1 ATOM 2187 O O . GLN B 2 8 ? 63.154 16.019 -18.235 1.00 29.67 ? 8 GLN B O 1 ATOM 2188 C CB . GLN B 2 8 ? 62.874 15.136 -15.436 1.00 32.02 ? 8 GLN B CB 1 ATOM 2189 C CG . GLN B 2 8 ? 62.744 15.043 -13.937 1.00 34.08 ? 8 GLN B CG 1 ATOM 2190 C CD . GLN B 2 8 ? 61.851 13.896 -13.528 1.00 37.99 ? 8 GLN B CD 1 ATOM 2191 O OE1 . GLN B 2 8 ? 60.665 14.090 -13.220 1.00 37.64 ? 8 GLN B OE1 1 ATOM 2192 N NE2 . GLN B 2 8 ? 62.399 12.676 -13.568 1.00 38.99 ? 8 GLN B NE2 1 ATOM 2193 N N . VAL B 2 9 ? 65.355 16.102 -17.685 1.00 28.11 ? 9 VAL B N 1 ATOM 2194 C CA . VAL B 2 9 ? 65.853 15.977 -19.066 1.00 26.45 ? 9 VAL B CA 1 ATOM 2195 C C . VAL B 2 9 ? 66.270 14.536 -19.345 1.00 25.50 ? 9 VAL B C 1 ATOM 2196 O O . VAL B 2 9 ? 66.948 13.925 -18.532 1.00 25.79 ? 9 VAL B O 1 ATOM 2197 C CB . VAL B 2 9 ? 67.057 16.914 -19.330 1.00 25.69 ? 9 VAL B CB 1 ATOM 2198 C CG1 . VAL B 2 9 ? 67.387 16.972 -20.820 1.00 25.68 ? 9 VAL B CG1 1 ATOM 2199 C CG2 . VAL B 2 9 ? 66.798 18.308 -18.773 1.00 24.76 ? 9 VAL B CG2 1 ATOM 2200 N N . TYR B 2 10 ? 65.855 13.995 -20.486 1.00 24.63 ? 10 TYR B N 1 ATOM 2201 C CA . TYR B 2 10 ? 66.149 12.603 -20.838 1.00 23.56 ? 10 TYR B CA 1 ATOM 2202 C C . TYR B 2 10 ? 65.967 12.421 -22.334 1.00 23.16 ? 10 TYR B C 1 ATOM 2203 O O . TYR B 2 10 ? 65.223 13.166 -22.944 1.00 22.32 ? 10 TYR B O 1 ATOM 2204 C CB . TYR B 2 10 ? 65.250 11.635 -20.052 1.00 24.05 ? 10 TYR B CB 1 ATOM 2205 C CG . TYR B 2 10 ? 63.760 11.919 -20.151 1.00 24.41 ? 10 TYR B CG 1 ATOM 2206 C CD1 . TYR B 2 10 ? 62.943 11.190 -21.015 1.00 24.56 ? 10 TYR B CD1 1 ATOM 2207 C CD2 . TYR B 2 10 ? 63.171 12.917 -19.381 1.00 25.21 ? 10 TYR B CD2 1 ATOM 2208 C CE1 . TYR B 2 10 ? 61.580 11.449 -21.111 1.00 25.23 ? 10 TYR B CE1 1 ATOM 2209 C CE2 . TYR B 2 10 ? 61.810 13.190 -19.477 1.00 26.15 ? 10 TYR B CE2 1 ATOM 2210 C CZ . TYR B 2 10 ? 61.024 12.452 -20.342 1.00 26.13 ? 10 TYR B CZ 1 ATOM 2211 O OH . TYR B 2 10 ? 59.677 12.731 -20.425 1.00 27.61 ? 10 TYR B OH 1 ATOM 2212 N N . SER B 2 11 ? 66.660 11.445 -22.921 1.00 24.46 ? 11 SER B N 1 ATOM 2213 C CA . SER B 2 11 ? 66.610 11.190 -24.373 1.00 25.73 ? 11 SER B CA 1 ATOM 2214 C C . SER B 2 11 ? 65.709 10.012 -24.729 1.00 26.43 ? 11 SER B C 1 ATOM 2215 O O . SER B 2 11 ? 65.578 9.067 -23.945 1.00 27.66 ? 11 SER B O 1 ATOM 2216 C CB . SER B 2 11 ? 68.012 10.946 -24.936 1.00 26.36 ? 11 SER B CB 1 ATOM 2217 O OG . SER B 2 11 ? 68.640 9.848 -24.289 1.00 27.86 ? 11 SER B OG 1 ATOM 2218 N N . ARG B 2 12 ? 65.103 10.076 -25.910 1.00 26.44 ? 12 ARG B N 1 ATOM 2219 C CA . ARG B 2 12 ? 64.130 9.086 -26.364 1.00 28.15 ? 12 ARG B CA 1 ATOM 2220 C C . ARG B 2 12 ? 64.769 7.727 -26.679 1.00 30.27 ? 12 ARG B C 1 ATOM 2221 O O . ARG B 2 12 ? 64.211 6.667 -26.362 1.00 30.11 ? 12 ARG B O 1 ATOM 2222 C CB . ARG B 2 12 ? 63.394 9.627 -27.595 1.00 28.46 ? 12 ARG B CB 1 ATOM 2223 C CG . ARG B 2 12 ? 62.509 8.627 -28.340 1.00 28.32 ? 12 ARG B CG 1 ATOM 2224 C CD . ARG B 2 12 ? 61.343 8.179 -27.466 1.00 27.74 ? 12 ARG B CD 1 ATOM 2225 N NE . ARG B 2 12 ? 60.455 7.260 -28.175 1.00 27.03 ? 12 ARG B NE 1 ATOM 2226 C CZ . ARG B 2 12 ? 60.678 5.955 -28.331 1.00 25.81 ? 12 ARG B CZ 1 ATOM 2227 N NH1 . ARG B 2 12 ? 61.773 5.387 -27.833 1.00 23.94 ? 12 ARG B NH1 1 ATOM 2228 N NH2 . ARG B 2 12 ? 59.790 5.218 -28.985 1.00 24.99 ? 12 ARG B NH2 1 ATOM 2229 N N . HIS B 2 13 ? 65.934 7.775 -27.315 1.00 33.20 ? 13 HIS B N 1 ATOM 2230 C CA . HIS B 2 13 ? 66.682 6.590 -27.692 1.00 35.62 ? 13 HIS B CA 1 ATOM 2231 C C . HIS B 2 13 ? 67.981 6.580 -26.930 1.00 37.38 ? 13 HIS B C 1 ATOM 2232 O O . HIS B 2 13 ? 68.359 7.605 -26.355 1.00 41.73 ? 13 HIS B O 1 ATOM 2233 C CB . HIS B 2 13 ? 66.934 6.616 -29.188 1.00 38.04 ? 13 HIS B CB 1 ATOM 2234 C CG . HIS B 2 13 ? 65.673 6.704 -30.021 1.00 39.69 ? 13 HIS B CG 1 ATOM 2235 N ND1 . HIS B 2 13 ? 64.779 5.694 -30.096 1.00 40.97 ? 13 HIS B ND1 1 ATOM 2236 C CD2 . HIS B 2 13 ? 65.189 7.720 -30.847 1.00 41.16 ? 13 HIS B CD2 1 ATOM 2237 C CE1 . HIS B 2 13 ? 63.766 6.045 -30.922 1.00 42.46 ? 13 HIS B CE1 1 ATOM 2238 N NE2 . HIS B 2 13 ? 64.018 7.287 -31.379 1.00 43.50 ? 13 HIS B NE2 1 ATOM 2239 N N . PRO B 2 14 ? 68.685 5.431 -26.887 1.00 37.16 ? 14 PRO B N 1 ATOM 2240 C CA . PRO B 2 14 ? 70.007 5.434 -26.238 1.00 37.55 ? 14 PRO B CA 1 ATOM 2241 C C . PRO B 2 14 ? 71.010 6.359 -26.966 1.00 38.09 ? 14 PRO B C 1 ATOM 2242 O O . PRO B 2 14 ? 71.079 6.339 -28.198 1.00 35.41 ? 14 PRO B O 1 ATOM 2243 C CB . PRO B 2 14 ? 70.448 3.961 -26.309 1.00 37.20 ? 14 PRO B CB 1 ATOM 2244 C CG . PRO B 2 14 ? 69.611 3.343 -27.393 1.00 37.54 ? 14 PRO B CG 1 ATOM 2245 C CD . PRO B 2 14 ? 68.306 4.091 -27.376 1.00 37.80 ? 14 PRO B CD 1 ATOM 2246 N N . PRO B 2 15 ? 71.781 7.162 -26.201 1.00 40.81 ? 15 PRO B N 1 ATOM 2247 C CA . PRO B 2 15 ? 72.600 8.249 -26.735 1.00 43.35 ? 15 PRO B CA 1 ATOM 2248 C C . PRO B 2 15 ? 73.890 7.780 -27.401 1.00 46.17 ? 15 PRO B C 1 ATOM 2249 O O . PRO B 2 15 ? 74.706 7.093 -26.784 1.00 47.05 ? 15 PRO B O 1 ATOM 2250 C CB . PRO B 2 15 ? 72.928 9.093 -25.488 1.00 43.63 ? 15 PRO B CB 1 ATOM 2251 C CG . PRO B 2 15 ? 72.227 8.423 -24.316 1.00 42.47 ? 15 PRO B CG 1 ATOM 2252 C CD . PRO B 2 15 ? 71.992 7.013 -24.752 1.00 42.82 ? 15 PRO B CD 1 ATOM 2253 N N . GLU B 2 16 ? 74.056 8.167 -28.659 1.00 49.34 ? 16 GLU B N 1 ATOM 2254 C CA . GLU B 2 16 ? 75.220 7.822 -29.457 1.00 52.07 ? 16 GLU B CA 1 ATOM 2255 C C . GLU B 2 16 ? 75.712 9.070 -30.172 1.00 51.89 ? 16 GLU B C 1 ATOM 2256 O O . GLU B 2 16 ? 74.978 9.653 -30.974 1.00 54.80 ? 16 GLU B O 1 ATOM 2257 C CB . GLU B 2 16 ? 74.838 6.789 -30.514 1.00 55.01 ? 16 GLU B CB 1 ATOM 2258 C CG . GLU B 2 16 ? 75.299 5.376 -30.246 1.00 62.59 ? 16 GLU B CG 1 ATOM 2259 C CD . GLU B 2 16 ? 75.491 4.584 -31.543 1.00 68.92 ? 16 GLU B CD 1 ATOM 2260 O OE1 . GLU B 2 16 ? 74.666 3.684 -31.823 1.00 73.39 ? 16 GLU B OE1 1 ATOM 2261 O OE2 . GLU B 2 16 ? 76.459 4.868 -32.292 1.00 67.29 ? 16 GLU B OE2 1 ATOM 2262 N N . ASN B 2 17 ? 76.949 9.476 -29.912 1.00 49.08 ? 17 ASN B N 1 ATOM 2263 C CA . ASN B 2 17 ? 77.527 10.608 -30.639 1.00 47.47 ? 17 ASN B CA 1 ATOM 2264 C C . ASN B 2 17 ? 77.374 10.474 -32.153 1.00 46.78 ? 17 ASN B C 1 ATOM 2265 O O . ASN B 2 17 ? 77.557 9.391 -32.710 1.00 44.45 ? 17 ASN B O 1 ATOM 2266 C CB . ASN B 2 17 ? 78.984 10.820 -30.251 1.00 46.70 ? 17 ASN B CB 1 ATOM 2267 C CG . ASN B 2 17 ? 79.181 10.851 -28.746 1.00 48.40 ? 17 ASN B CG 1 ATOM 2268 O OD1 . ASN B 2 17 ? 78.576 11.658 -28.034 1.00 48.36 ? 17 ASN B OD1 1 ATOM 2269 N ND2 . ASN B 2 17 ? 80.025 9.959 -28.252 1.00 48.60 ? 17 ASN B ND2 1 ATOM 2270 N N . GLY B 2 18 ? 76.989 11.570 -32.802 1.00 46.47 ? 18 GLY B N 1 ATOM 2271 C CA . GLY B 2 18 ? 76.860 11.598 -34.258 1.00 47.86 ? 18 GLY B CA 1 ATOM 2272 C C . GLY B 2 18 ? 75.522 11.103 -34.768 1.00 49.26 ? 18 GLY B C 1 ATOM 2273 O O . GLY B 2 18 ? 75.127 11.407 -35.897 1.00 49.39 ? 18 GLY B O 1 ATOM 2274 N N . LYS B 2 19 ? 74.816 10.356 -33.924 1.00 51.71 ? 19 LYS B N 1 ATOM 2275 C CA . LYS B 2 19 ? 73.522 9.770 -34.278 1.00 52.29 ? 19 LYS B CA 1 ATOM 2276 C C . LYS B 2 19 ? 72.341 10.668 -33.858 1.00 50.52 ? 19 LYS B C 1 ATOM 2277 O O . LYS B 2 19 ? 72.117 10.870 -32.659 1.00 48.81 ? 19 LYS B O 1 ATOM 2278 C CB . LYS B 2 19 ? 73.405 8.395 -33.622 1.00 54.96 ? 19 LYS B CB 1 ATOM 2279 C CG . LYS B 2 19 ? 72.652 7.368 -34.438 1.00 61.29 ? 19 LYS B CG 1 ATOM 2280 C CD . LYS B 2 19 ? 72.808 5.977 -33.827 1.00 63.26 ? 19 LYS B CD 1 ATOM 2281 C CE . LYS B 2 19 ? 72.142 4.910 -34.681 1.00 64.20 ? 19 LYS B CE 1 ATOM 2282 N NZ . LYS B 2 19 ? 70.662 4.989 -34.584 1.00 63.14 ? 19 LYS B NZ 1 ATOM 2283 N N . PRO B 2 20 ? 71.592 11.219 -34.841 1.00 49.31 ? 20 PRO B N 1 ATOM 2284 C CA . PRO B 2 20 ? 70.371 12.005 -34.572 1.00 47.88 ? 20 PRO B CA 1 ATOM 2285 C C . PRO B 2 20 ? 69.393 11.276 -33.639 1.00 44.84 ? 20 PRO B C 1 ATOM 2286 O O . PRO B 2 20 ? 69.316 10.047 -33.674 1.00 49.02 ? 20 PRO B O 1 ATOM 2287 C CB . PRO B 2 20 ? 69.748 12.200 -35.966 1.00 48.02 ? 20 PRO B CB 1 ATOM 2288 C CG . PRO B 2 20 ? 70.518 11.312 -36.893 1.00 48.83 ? 20 PRO B CG 1 ATOM 2289 C CD . PRO B 2 20 ? 71.877 11.156 -36.285 1.00 49.69 ? 20 PRO B CD 1 ATOM 2290 N N . ASN B 2 21 ? 68.655 12.042 -32.834 1.00 40.35 ? 21 ASN B N 1 ATOM 2291 C CA . ASN B 2 21 ? 67.914 11.554 -31.654 1.00 36.67 ? 21 ASN B CA 1 ATOM 2292 C C . ASN B 2 21 ? 66.839 12.606 -31.279 1.00 35.50 ? 21 ASN B C 1 ATOM 2293 O O . ASN B 2 21 ? 66.669 13.602 -31.989 1.00 36.60 ? 21 ASN B O 1 ATOM 2294 C CB . ASN B 2 21 ? 68.910 11.341 -30.499 1.00 34.32 ? 21 ASN B CB 1 ATOM 2295 C CG . ASN B 2 21 ? 68.408 10.381 -29.410 1.00 34.50 ? 21 ASN B CG 1 ATOM 2296 O OD1 . ASN B 2 21 ? 67.210 10.246 -29.169 1.00 35.02 ? 21 ASN B OD1 1 ATOM 2297 N ND2 . ASN B 2 21 ? 69.347 9.742 -28.720 1.00 33.36 ? 21 ASN B ND2 1 ATOM 2298 N N . ILE B 2 22 ? 66.088 12.377 -30.203 1.00 32.40 ? 22 ILE B N 1 ATOM 2299 C CA . ILE B 2 22 ? 65.147 13.373 -29.700 1.00 29.89 ? 22 ILE B CA 1 ATOM 2300 C C . ILE B 2 22 ? 65.369 13.499 -28.217 1.00 29.54 ? 22 ILE B C 1 ATOM 2301 O O . ILE B 2 22 ? 65.547 12.497 -27.526 1.00 29.59 ? 22 ILE B O 1 ATOM 2302 C CB . ILE B 2 22 ? 63.677 13.015 -29.991 1.00 30.01 ? 22 ILE B CB 1 ATOM 2303 C CG1 . ILE B 2 22 ? 63.373 13.213 -31.482 1.00 29.80 ? 22 ILE B CG1 1 ATOM 2304 C CG2 . ILE B 2 22 ? 62.730 13.879 -29.139 1.00 29.24 ? 22 ILE B CG2 1 ATOM 2305 C CD1 . ILE B 2 22 ? 62.243 12.372 -32.010 1.00 28.71 ? 22 ILE B CD1 1 ATOM 2306 N N . LEU B 2 23 ? 65.378 14.741 -27.741 1.00 29.59 ? 23 LEU B N 1 ATOM 2307 C CA . LEU B 2 23 ? 65.667 15.053 -26.345 1.00 28.74 ? 23 LEU B CA 1 ATOM 2308 C C . LEU B 2 23 ? 64.434 15.678 -25.697 1.00 28.77 ? 23 LEU B C 1 ATOM 2309 O O . LEU B 2 23 ? 63.795 16.556 -26.288 1.00 29.46 ? 23 LEU B O 1 ATOM 2310 C CB . LEU B 2 23 ? 66.865 15.992 -26.261 1.00 27.82 ? 23 LEU B CB 1 ATOM 2311 C CG . LEU B 2 23 ? 67.368 16.480 -24.907 1.00 28.03 ? 23 LEU B CG 1 ATOM 2312 C CD1 . LEU B 2 23 ? 68.284 15.467 -24.232 1.00 27.69 ? 23 LEU B CD1 1 ATOM 2313 C CD2 . LEU B 2 23 ? 68.095 17.788 -25.118 1.00 27.50 ? 23 LEU B CD2 1 ATOM 2314 N N . ASN B 2 24 ? 64.110 15.201 -24.493 1.00 28.05 ? 24 ASN B N 1 ATOM 2315 C CA . ASN B 2 24 ? 62.892 15.557 -23.776 1.00 26.98 ? 24 ASN B CA 1 ATOM 2316 C C . ASN B 2 24 ? 63.172 16.377 -22.543 1.00 27.80 ? 24 ASN B C 1 ATOM 2317 O O . ASN B 2 24 ? 64.104 16.096 -21.775 1.00 28.26 ? 24 ASN B O 1 ATOM 2318 C CB . ASN B 2 24 ? 62.145 14.304 -23.329 1.00 27.45 ? 24 ASN B CB 1 ATOM 2319 C CG . ASN B 2 24 ? 61.685 13.444 -24.485 1.00 28.55 ? 24 ASN B CG 1 ATOM 2320 O OD1 . ASN B 2 24 ? 61.422 13.944 -25.579 1.00 28.95 ? 24 ASN B OD1 1 ATOM 2321 N ND2 . ASN B 2 24 ? 61.574 12.135 -24.244 1.00 28.12 ? 24 ASN B ND2 1 ATOM 2322 N N . CYS B 2 25 ? 62.349 17.392 -22.352 1.00 28.81 ? 25 CYS B N 1 ATOM 2323 C CA . CYS B 2 25 ? 62.334 18.136 -21.117 1.00 30.72 ? 25 CYS B CA 1 ATOM 2324 C C . CYS B 2 25 ? 60.933 18.031 -20.528 1.00 31.03 ? 25 CYS B C 1 ATOM 2325 O O . CYS B 2 25 ? 59.961 18.503 -21.124 1.00 32.36 ? 25 CYS B O 1 ATOM 2326 C CB . CYS B 2 25 ? 62.706 19.586 -21.357 1.00 32.91 ? 25 CYS B CB 1 ATOM 2327 S SG . CYS B 2 25 ? 62.674 20.542 -19.835 1.00 37.42 ? 25 CYS B SG 1 ATOM 2328 N N . TYR B 2 26 ? 60.834 17.386 -19.373 1.00 30.09 ? 26 TYR B N 1 ATOM 2329 C CA . TYR B 2 26 ? 59.552 17.169 -18.731 1.00 29.31 ? 26 TYR B CA 1 ATOM 2330 C C . TYR B 2 26 ? 59.444 18.037 -17.493 1.00 29.30 ? 26 TYR B C 1 ATOM 2331 O O . TYR B 2 26 ? 60.189 17.834 -16.516 1.00 28.07 ? 26 TYR B O 1 ATOM 2332 C CB . TYR B 2 26 ? 59.376 15.704 -18.358 1.00 28.11 ? 26 TYR B CB 1 ATOM 2333 C CG . TYR B 2 26 ? 57.980 15.341 -17.887 1.00 27.97 ? 26 TYR B CG 1 ATOM 2334 C CD1 . TYR B 2 26 ? 56.843 15.783 -18.579 1.00 27.93 ? 26 TYR B CD1 1 ATOM 2335 C CD2 . TYR B 2 26 ? 57.794 14.516 -16.772 1.00 27.68 ? 26 TYR B CD2 1 ATOM 2336 C CE1 . TYR B 2 26 ? 55.562 15.418 -18.163 1.00 27.84 ? 26 TYR B CE1 1 ATOM 2337 C CE2 . TYR B 2 26 ? 56.525 14.147 -16.349 1.00 27.29 ? 26 TYR B CE2 1 ATOM 2338 C CZ . TYR B 2 26 ? 55.418 14.597 -17.046 1.00 28.15 ? 26 TYR B CZ 1 ATOM 2339 O OH . TYR B 2 26 ? 54.164 14.232 -16.624 1.00 28.74 ? 26 TYR B OH 1 ATOM 2340 N N . VAL B 2 27 ? 58.503 18.988 -17.547 1.00 28.59 ? 27 VAL B N 1 ATOM 2341 C CA . VAL B 2 27 ? 58.301 19.982 -16.489 1.00 28.26 ? 27 VAL B CA 1 ATOM 2342 C C . VAL B 2 27 ? 56.993 19.753 -15.732 1.00 28.52 ? 27 VAL B C 1 ATOM 2343 O O . VAL B 2 27 ? 55.913 19.782 -16.325 1.00 28.92 ? 27 VAL B O 1 ATOM 2344 C CB . VAL B 2 27 ? 58.360 21.414 -17.059 1.00 26.68 ? 27 VAL B CB 1 ATOM 2345 C CG1 . VAL B 2 27 ? 58.290 22.431 -15.948 1.00 26.43 ? 27 VAL B CG1 1 ATOM 2346 C CG2 . VAL B 2 27 ? 59.629 21.605 -17.848 1.00 25.55 ? 27 VAL B CG2 1 ATOM 2347 N N . THR B 2 28 ? 57.098 19.530 -14.424 1.00 29.67 ? 28 THR B N 1 ATOM 2348 C CA . THR B 2 28 ? 55.950 19.104 -13.613 1.00 31.32 ? 28 THR B CA 1 ATOM 2349 C C . THR B 2 28 ? 55.838 19.842 -12.294 1.00 33.39 ? 28 THR B C 1 ATOM 2350 O O . THR B 2 28 ? 56.681 20.682 -11.979 1.00 34.33 ? 28 THR B O 1 ATOM 2351 C CB . THR B 2 28 ? 56.052 17.627 -13.240 1.00 30.28 ? 28 THR B CB 1 ATOM 2352 O OG1 . THR B 2 28 ? 57.371 17.367 -12.754 1.00 30.06 ? 28 THR B OG1 1 ATOM 2353 C CG2 . THR B 2 28 ? 55.753 16.740 -14.425 1.00 29.02 ? 28 THR B CG2 1 ATOM 2354 N N . GLN B 2 29 ? 54.789 19.498 -11.537 1.00 35.74 ? 29 GLN B N 1 ATOM 2355 C CA . GLN B 2 29 ? 54.565 19.937 -10.148 1.00 37.83 ? 29 GLN B CA 1 ATOM 2356 C C . GLN B 2 29 ? 54.375 21.438 -9.925 1.00 36.24 ? 29 GLN B C 1 ATOM 2357 O O . GLN B 2 29 ? 54.480 21.899 -8.784 1.00 40.39 ? 29 GLN B O 1 ATOM 2358 C CB . GLN B 2 29 ? 55.671 19.412 -9.196 1.00 42.51 ? 29 GLN B CB 1 ATOM 2359 C CG . GLN B 2 29 ? 55.768 17.892 -9.056 1.00 49.21 ? 29 GLN B CG 1 ATOM 2360 C CD . GLN B 2 29 ? 54.417 17.211 -8.792 1.00 56.07 ? 29 GLN B CD 1 ATOM 2361 O OE1 . GLN B 2 29 ? 53.637 17.635 -7.923 1.00 60.34 ? 29 GLN B OE1 1 ATOM 2362 N NE2 . GLN B 2 29 ? 54.144 16.143 -9.540 1.00 56.46 ? 29 GLN B NE2 1 ATOM 2363 N N . PHE B 2 30 ? 54.077 22.202 -10.975 1.00 31.76 ? 30 PHE B N 1 ATOM 2364 C CA . PHE B 2 30 ? 53.998 23.670 -10.837 1.00 29.35 ? 30 PHE B CA 1 ATOM 2365 C C . PHE B 2 30 ? 52.587 24.271 -10.800 1.00 27.92 ? 30 PHE B C 1 ATOM 2366 O O . PHE B 2 30 ? 51.681 23.804 -11.484 1.00 28.17 ? 30 PHE B O 1 ATOM 2367 C CB . PHE B 2 30 ? 54.844 24.365 -11.914 1.00 28.13 ? 30 PHE B CB 1 ATOM 2368 C CG . PHE B 2 30 ? 54.427 24.049 -13.327 1.00 27.17 ? 30 PHE B CG 1 ATOM 2369 C CD1 . PHE B 2 30 ? 54.897 22.906 -13.969 1.00 26.57 ? 30 PHE B CD1 1 ATOM 2370 C CD2 . PHE B 2 30 ? 53.572 24.908 -14.022 1.00 26.64 ? 30 PHE B CD2 1 ATOM 2371 C CE1 . PHE B 2 30 ? 54.512 22.613 -15.286 1.00 26.96 ? 30 PHE B CE1 1 ATOM 2372 C CE2 . PHE B 2 30 ? 53.185 24.630 -15.334 1.00 25.95 ? 30 PHE B CE2 1 ATOM 2373 C CZ . PHE B 2 30 ? 53.660 23.481 -15.971 1.00 26.32 ? 30 PHE B CZ 1 ATOM 2374 N N . HIS B 2 31 ? 52.426 25.305 -9.987 0.50 27.45 ? 31 HIS B N 1 ATOM 2375 C CA . HIS B 2 31 ? 51.214 26.099 -9.951 0.50 27.29 ? 31 HIS B CA 1 ATOM 2376 C C . HIS B 2 31 ? 51.656 27.490 -9.634 0.50 27.75 ? 31 HIS B C 1 ATOM 2377 O O . HIS B 2 31 ? 52.517 27.673 -8.781 0.50 27.23 ? 31 HIS B O 1 ATOM 2378 C CB . HIS B 2 31 ? 50.244 25.583 -8.885 0.50 26.46 ? 31 HIS B CB 1 ATOM 2379 C CG . HIS B 2 31 ? 48.808 25.990 -9.129 0.50 26.53 ? 31 HIS B CG 1 ATOM 2380 N ND1 . HIS B 2 31 ? 48.362 27.248 -8.919 0.50 26.49 ? 31 HIS B ND1 1 ATOM 2381 C CD2 . HIS B 2 31 ? 47.714 25.262 -9.602 0.50 26.55 ? 31 HIS B CD2 1 ATOM 2382 C CE1 . HIS B 2 31 ? 47.053 27.325 -9.237 0.50 25.87 ? 31 HIS B CE1 1 ATOM 2383 N NE2 . HIS B 2 31 ? 46.655 26.111 -9.654 0.50 26.52 ? 31 HIS B NE2 1 ATOM 2384 N N . PRO B 2 32 ? 51.100 28.503 -10.317 1.00 29.76 ? 32 PRO B N 1 ATOM 2385 C CA . PRO B 2 32 ? 50.121 28.538 -11.412 1.00 31.27 ? 32 PRO B CA 1 ATOM 2386 C C . PRO B 2 32 ? 50.701 28.042 -12.747 1.00 32.22 ? 32 PRO B C 1 ATOM 2387 O O . PRO B 2 32 ? 51.903 27.779 -12.818 1.00 32.96 ? 32 PRO B O 1 ATOM 2388 C CB . PRO B 2 32 ? 49.770 30.030 -11.503 1.00 30.29 ? 32 PRO B CB 1 ATOM 2389 C CG . PRO B 2 32 ? 51.006 30.714 -11.060 1.00 30.71 ? 32 PRO B CG 1 ATOM 2390 C CD . PRO B 2 32 ? 51.429 29.872 -9.879 1.00 31.12 ? 32 PRO B CD 1 ATOM 2391 N N . PRO B 2 33 ? 49.846 27.906 -13.788 1.00 32.34 ? 33 PRO B N 1 ATOM 2392 C CA . PRO B 2 33 ? 50.197 27.359 -15.107 1.00 31.48 ? 33 PRO B CA 1 ATOM 2393 C C . PRO B 2 33 ? 51.059 28.223 -16.035 1.00 33.29 ? 33 PRO B C 1 ATOM 2394 O O . PRO B 2 33 ? 51.567 27.709 -17.037 1.00 33.08 ? 33 PRO B O 1 ATOM 2395 C CB . PRO B 2 33 ? 48.829 27.125 -15.766 1.00 30.48 ? 33 PRO B CB 1 ATOM 2396 C CG . PRO B 2 33 ? 47.916 28.049 -15.102 1.00 31.53 ? 33 PRO B CG 1 ATOM 2397 C CD . PRO B 2 33 ? 48.390 28.122 -13.671 1.00 31.98 ? 33 PRO B CD 1 ATOM 2398 N N . HIS B 2 34 ? 51.230 29.513 -15.754 1.00 35.29 ? 34 HIS B N 1 ATOM 2399 C CA . HIS B 2 34 ? 52.031 30.318 -16.677 1.00 37.26 ? 34 HIS B CA 1 ATOM 2400 C C . HIS B 2 34 ? 53.494 29.992 -16.554 1.00 37.18 ? 34 HIS B C 1 ATOM 2401 O O . HIS B 2 34 ? 54.069 30.123 -15.468 1.00 37.82 ? 34 HIS B O 1 ATOM 2402 C CB . HIS B 2 34 ? 51.797 31.803 -16.502 1.00 39.25 ? 34 HIS B CB 1 ATOM 2403 C CG . HIS B 2 34 ? 52.418 32.642 -17.601 1.00 45.16 ? 34 HIS B CG 1 ATOM 2404 N ND1 . HIS B 2 34 ? 53.510 33.419 -17.402 1.00 45.83 ? 34 HIS B ND1 1 ATOM 2405 C CD2 . HIS B 2 34 ? 52.069 32.791 -18.947 1.00 46.35 ? 34 HIS B CD2 1 ATOM 2406 C CE1 . HIS B 2 34 ? 53.832 34.044 -18.551 1.00 45.51 ? 34 HIS B CE1 1 ATOM 2407 N NE2 . HIS B 2 34 ? 52.952 33.657 -19.497 1.00 47.92 ? 34 HIS B NE2 1 ATOM 2408 N N . ILE B 2 35 ? 54.102 29.575 -17.668 1.00 34.68 ? 35 ILE B N 1 ATOM 2409 C CA . ILE B 2 35 ? 55.498 29.121 -17.687 1.00 33.63 ? 35 ILE B CA 1 ATOM 2410 C C . ILE B 2 35 ? 56.218 29.432 -19.013 1.00 32.79 ? 35 ILE B C 1 ATOM 2411 O O . ILE B 2 35 ? 55.605 29.423 -20.078 1.00 32.78 ? 35 ILE B O 1 ATOM 2412 C CB . ILE B 2 35 ? 55.594 27.585 -17.357 1.00 33.81 ? 35 ILE B CB 1 ATOM 2413 C CG1 . ILE B 2 35 ? 56.873 27.261 -16.572 1.00 32.94 ? 35 ILE B CG1 1 ATOM 2414 C CG2 . ILE B 2 35 ? 55.462 26.716 -18.632 1.00 32.62 ? 35 ILE B CG2 1 ATOM 2415 C CD1 . ILE B 2 35 ? 56.797 25.978 -15.760 1.00 31.04 ? 35 ILE B CD1 1 ATOM 2416 N N . GLU B 2 36 ? 57.515 29.714 -18.935 1.00 32.97 ? 36 GLU B N 1 ATOM 2417 C CA . GLU B 2 36 ? 58.362 29.850 -20.124 1.00 33.26 ? 36 GLU B CA 1 ATOM 2418 C C . GLU B 2 36 ? 59.418 28.746 -20.095 1.00 34.57 ? 36 GLU B C 1 ATOM 2419 O O . GLU B 2 36 ? 60.213 28.638 -19.144 1.00 35.50 ? 36 GLU B O 1 ATOM 2420 C CB . GLU B 2 36 ? 59.011 31.240 -20.207 1.00 32.24 ? 36 GLU B CB 1 ATOM 2421 N N . ILE B 2 37 ? 59.391 27.903 -21.123 1.00 34.56 ? 37 ILE B N 1 ATOM 2422 C CA . ILE B 2 37 ? 60.287 26.757 -21.210 1.00 33.86 ? 37 ILE B CA 1 ATOM 2423 C C . ILE B 2 37 ? 61.094 26.866 -22.481 1.00 34.56 ? 37 ILE B C 1 ATOM 2424 O O . ILE B 2 37 ? 60.546 27.015 -23.571 1.00 34.41 ? 37 ILE B O 1 ATOM 2425 C CB . ILE B 2 37 ? 59.529 25.412 -21.161 1.00 32.74 ? 37 ILE B CB 1 ATOM 2426 C CG1 . ILE B 2 37 ? 58.985 25.166 -19.752 1.00 31.63 ? 37 ILE B CG1 1 ATOM 2427 C CG2 . ILE B 2 37 ? 60.449 24.275 -21.507 1.00 33.29 ? 37 ILE B CG2 1 ATOM 2428 C CD1 . ILE B 2 37 ? 58.008 24.053 -19.671 1.00 29.15 ? 37 ILE B CD1 1 ATOM 2429 N N . GLN B 2 38 ? 62.409 26.811 -22.318 1.00 36.20 ? 38 GLN B N 1 ATOM 2430 C CA . GLN B 2 38 ? 63.333 26.913 -23.426 1.00 36.32 ? 38 GLN B CA 1 ATOM 2431 C C . GLN B 2 38 ? 64.264 25.719 -23.406 1.00 35.39 ? 38 GLN B C 1 ATOM 2432 O O . GLN B 2 38 ? 64.638 25.227 -22.337 1.00 35.63 ? 38 GLN B O 1 ATOM 2433 C CB . GLN B 2 38 ? 64.177 28.159 -23.267 1.00 38.44 ? 38 GLN B CB 1 ATOM 2434 C CG . GLN B 2 38 ? 63.481 29.476 -23.483 1.00 39.61 ? 38 GLN B CG 1 ATOM 2435 C CD . GLN B 2 38 ? 64.477 30.632 -23.409 1.00 42.46 ? 38 GLN B CD 1 ATOM 2436 O OE1 . GLN B 2 38 ? 65.459 30.584 -22.644 1.00 42.19 ? 38 GLN B OE1 1 ATOM 2437 N NE2 . GLN B 2 38 ? 64.242 31.669 -24.215 1.00 43.81 ? 38 GLN B NE2 1 ATOM 2438 N N . MET B 2 39 ? 64.652 25.265 -24.587 1.00 33.70 ? 39 MET B N 1 ATOM 2439 C CA . MET B 2 39 ? 65.646 24.209 -24.688 1.00 34.16 ? 39 MET B CA 1 ATOM 2440 C C . MET B 2 39 ? 66.910 24.782 -25.335 1.00 34.40 ? 39 MET B C 1 ATOM 2441 O O . MET B 2 39 ? 66.867 25.315 -26.449 1.00 34.68 ? 39 MET B O 1 ATOM 2442 C CB . MET B 2 39 ? 65.096 23.014 -25.473 1.00 33.85 ? 39 MET B CB 1 ATOM 2443 C CG . MET B 2 39 ? 63.839 22.370 -24.866 1.00 33.59 ? 39 MET B CG 1 ATOM 2444 S SD . MET B 2 39 ? 63.480 20.701 -25.493 1.00 33.82 ? 39 MET B SD 1 ATOM 2445 C CE . MET B 2 39 ? 64.719 19.718 -24.638 1.00 31.10 ? 39 MET B CE 1 ATOM 2446 N N . LEU B 2 40 ? 68.026 24.677 -24.623 1.00 34.03 ? 40 LEU B N 1 ATOM 2447 C CA . LEU B 2 40 ? 69.271 25.334 -25.014 1.00 34.30 ? 40 LEU B CA 1 ATOM 2448 C C . LEU B 2 40 ? 70.343 24.374 -25.519 1.00 35.77 ? 40 LEU B C 1 ATOM 2449 O O . LEU B 2 40 ? 70.644 23.356 -24.875 1.00 35.82 ? 40 LEU B O 1 ATOM 2450 C CB . LEU B 2 40 ? 69.852 26.100 -23.825 1.00 33.95 ? 40 LEU B CB 1 ATOM 2451 C CG . LEU B 2 40 ? 69.009 27.124 -23.067 1.00 33.72 ? 40 LEU B CG 1 ATOM 2452 C CD1 . LEU B 2 40 ? 69.729 27.506 -21.786 1.00 32.10 ? 40 LEU B CD1 1 ATOM 2453 C CD2 . LEU B 2 40 ? 68.718 28.360 -23.944 1.00 33.57 ? 40 LEU B CD2 1 ATOM 2454 N N . LYS B 2 41 ? 70.929 24.716 -26.664 1.00 36.02 ? 41 LYS B N 1 ATOM 2455 C CA . LYS B 2 41 ? 72.158 24.077 -27.119 1.00 36.65 ? 41 LYS B CA 1 ATOM 2456 C C . LYS B 2 41 ? 73.341 25.003 -26.817 1.00 39.08 ? 41 LYS B C 1 ATOM 2457 O O . LYS B 2 41 ? 73.391 26.143 -27.302 1.00 40.35 ? 41 LYS B O 1 ATOM 2458 C CB . LYS B 2 41 ? 72.091 23.767 -28.612 1.00 34.10 ? 41 LYS B CB 1 ATOM 2459 C CG . LYS B 2 41 ? 73.120 22.768 -29.061 1.00 32.83 ? 41 LYS B CG 1 ATOM 2460 C CD . LYS B 2 41 ? 73.128 22.625 -30.564 1.00 33.15 ? 41 LYS B CD 1 ATOM 2461 C CE . LYS B 2 41 ? 74.333 21.808 -31.006 1.00 33.74 ? 41 LYS B CE 1 ATOM 2462 N NZ . LYS B 2 41 ? 74.600 21.936 -32.451 1.00 34.76 ? 41 LYS B NZ 1 ATOM 2463 N N . ASN B 2 42 ? 74.276 24.520 -26.000 1.00 39.48 ? 42 ASN B N 1 ATOM 2464 C CA . ASN B 2 42 ? 75.468 25.288 -25.652 1.00 40.62 ? 42 ASN B CA 1 ATOM 2465 C C . ASN B 2 42 ? 75.099 26.682 -25.178 1.00 41.85 ? 42 ASN B C 1 ATOM 2466 O O . ASN B 2 42 ? 75.780 27.654 -25.502 1.00 46.42 ? 42 ASN B O 1 ATOM 2467 C CB . ASN B 2 42 ? 76.408 25.399 -26.860 1.00 40.70 ? 42 ASN B CB 1 ATOM 2468 C CG . ASN B 2 42 ? 77.095 24.098 -27.191 1.00 40.25 ? 42 ASN B CG 1 ATOM 2469 O OD1 . ASN B 2 42 ? 77.519 23.359 -26.299 1.00 40.67 ? 42 ASN B OD1 1 ATOM 2470 N ND2 . ASN B 2 42 ? 77.221 23.813 -28.479 1.00 39.41 ? 42 ASN B ND2 1 ATOM 2471 N N . GLY B 2 43 ? 74.002 26.780 -24.436 1.00 40.96 ? 43 GLY B N 1 ATOM 2472 C CA . GLY B 2 43 ? 73.532 28.062 -23.942 1.00 40.21 ? 43 GLY B CA 1 ATOM 2473 C C . GLY B 2 43 ? 72.623 28.819 -24.892 1.00 40.14 ? 43 GLY B C 1 ATOM 2474 O O . GLY B 2 43 ? 71.973 29.760 -24.475 1.00 40.27 ? 43 GLY B O 1 ATOM 2475 N N . LYS B 2 44 ? 72.569 28.424 -26.161 1.00 41.18 ? 44 LYS B N 1 ATOM 2476 C CA . LYS B 2 44 ? 71.726 29.127 -27.140 1.00 43.66 ? 44 LYS B CA 1 ATOM 2477 C C . LYS B 2 44 ? 70.388 28.419 -27.373 1.00 45.69 ? 44 LYS B C 1 ATOM 2478 O O . LYS B 2 44 ? 70.324 27.189 -27.468 1.00 45.70 ? 44 LYS B O 1 ATOM 2479 C CB . LYS B 2 44 ? 72.460 29.312 -28.474 1.00 46.14 ? 44 LYS B CB 1 ATOM 2480 C CG . LYS B 2 44 ? 73.588 30.355 -28.449 1.00 50.11 ? 44 LYS B CG 1 ATOM 2481 C CD . LYS B 2 44 ? 74.879 29.840 -29.112 1.00 50.78 ? 44 LYS B CD 1 ATOM 2482 C CE . LYS B 2 44 ? 74.867 30.014 -30.633 1.00 52.88 ? 44 LYS B CE 1 ATOM 2483 N NZ . LYS B 2 44 ? 75.973 29.238 -31.283 1.00 54.05 ? 44 LYS B NZ 1 ATOM 2484 N N . LYS B 2 45 ? 69.329 29.216 -27.472 1.00 44.53 ? 45 LYS B N 1 ATOM 2485 C CA . LYS B 2 45 ? 67.985 28.724 -27.724 1.00 44.31 ? 45 LYS B CA 1 ATOM 2486 C C . LYS B 2 45 ? 67.878 27.925 -29.034 1.00 42.68 ? 45 LYS B C 1 ATOM 2487 O O . LYS B 2 45 ? 68.165 28.439 -30.117 1.00 40.10 ? 45 LYS B O 1 ATOM 2488 C CB . LYS B 2 45 ? 66.999 29.901 -27.714 1.00 48.41 ? 45 LYS B CB 1 ATOM 2489 C CG . LYS B 2 45 ? 65.521 29.505 -27.642 1.00 52.83 ? 45 LYS B CG 1 ATOM 2490 C CD . LYS B 2 45 ? 64.594 30.708 -27.849 1.00 54.84 ? 45 LYS B CD 1 ATOM 2491 C CE . LYS B 2 45 ? 63.153 30.268 -28.124 1.00 55.71 ? 45 LYS B CE 1 ATOM 2492 N NZ . LYS B 2 45 ? 62.236 31.427 -28.307 1.00 56.81 ? 45 LYS B NZ 1 ATOM 2493 N N . ILE B 2 46 ? 67.468 26.661 -28.909 1.00 41.82 ? 46 ILE B N 1 ATOM 2494 C CA . ILE B 2 46 ? 67.169 25.797 -30.055 1.00 41.01 ? 46 ILE B CA 1 ATOM 2495 C C . ILE B 2 46 ? 65.831 26.262 -30.642 1.00 43.52 ? 46 ILE B C 1 ATOM 2496 O O . ILE B 2 46 ? 64.936 26.655 -29.888 1.00 42.98 ? 46 ILE B O 1 ATOM 2497 C CB . ILE B 2 46 ? 67.134 24.285 -29.652 1.00 38.10 ? 46 ILE B CB 1 ATOM 2498 C CG1 . ILE B 2 46 ? 68.424 23.895 -28.913 1.00 38.13 ? 46 ILE B CG1 1 ATOM 2499 C CG2 . ILE B 2 46 ? 66.971 23.386 -30.868 1.00 36.45 ? 46 ILE B CG2 1 ATOM 2500 C CD1 . ILE B 2 46 ? 68.376 22.577 -28.115 1.00 35.83 ? 46 ILE B CD1 1 ATOM 2501 N N . PRO B 2 47 ? 65.695 26.252 -31.988 1.00 47.12 ? 47 PRO B N 1 ATOM 2502 C CA . PRO B 2 47 ? 64.501 26.868 -32.578 1.00 46.74 ? 47 PRO B CA 1 ATOM 2503 C C . PRO B 2 47 ? 63.290 25.951 -32.785 1.00 46.64 ? 47 PRO B C 1 ATOM 2504 O O . PRO B 2 47 ? 62.176 26.353 -32.449 1.00 49.06 ? 47 PRO B O 1 ATOM 2505 C CB . PRO B 2 47 ? 65.015 27.414 -33.922 1.00 48.52 ? 47 PRO B CB 1 ATOM 2506 C CG . PRO B 2 47 ? 66.505 27.013 -34.009 1.00 46.75 ? 47 PRO B CG 1 ATOM 2507 C CD . PRO B 2 47 ? 66.685 25.912 -33.027 1.00 46.52 ? 47 PRO B CD 1 ATOM 2508 N N . LYS B 2 48 ? 63.480 24.750 -33.329 1.00 46.13 ? 48 LYS B N 1 ATOM 2509 C CA . LYS B 2 48 ? 62.326 23.878 -33.639 1.00 49.13 ? 48 LYS B CA 1 ATOM 2510 C C . LYS B 2 48 ? 61.897 22.990 -32.437 1.00 49.86 ? 48 LYS B C 1 ATOM 2511 O O . LYS B 2 48 ? 62.033 21.752 -32.474 1.00 51.78 ? 48 LYS B O 1 ATOM 2512 C CB . LYS B 2 48 ? 62.585 23.046 -34.915 1.00 45.77 ? 48 LYS B CB 1 ATOM 2513 N N . VAL B 2 49 ? 61.385 23.629 -31.379 1.00 44.73 ? 49 VAL B N 1 ATOM 2514 C CA . VAL B 2 49 ? 61.047 22.935 -30.122 1.00 39.67 ? 49 VAL B CA 1 ATOM 2515 C C . VAL B 2 49 ? 59.548 22.731 -30.030 1.00 39.62 ? 49 VAL B C 1 ATOM 2516 O O . VAL B 2 49 ? 58.800 23.703 -29.929 1.00 39.79 ? 49 VAL B O 1 ATOM 2517 C CB . VAL B 2 49 ? 61.519 23.727 -28.873 1.00 37.37 ? 49 VAL B CB 1 ATOM 2518 C CG1 . VAL B 2 49 ? 61.094 23.043 -27.593 1.00 35.02 ? 49 VAL B CG1 1 ATOM 2519 C CG2 . VAL B 2 49 ? 63.023 23.901 -28.877 1.00 38.05 ? 49 VAL B CG2 1 ATOM 2520 N N . GLU B 2 50 ? 59.109 21.475 -30.060 1.00 39.29 ? 50 GLU B N 1 ATOM 2521 C CA . GLU B 2 50 ? 57.681 21.157 -29.965 1.00 39.86 ? 50 GLU B CA 1 ATOM 2522 C C . GLU B 2 50 ? 57.203 21.051 -28.514 1.00 35.74 ? 50 GLU B C 1 ATOM 2523 O O . GLU B 2 50 ? 57.935 20.577 -27.647 1.00 35.56 ? 50 GLU B O 1 ATOM 2524 C CB . GLU B 2 50 ? 57.362 19.857 -30.709 1.00 44.80 ? 50 GLU B CB 1 ATOM 2525 C CG . GLU B 2 50 ? 57.511 19.896 -32.228 1.00 49.08 ? 50 GLU B CG 1 ATOM 2526 C CD . GLU B 2 50 ? 57.354 18.503 -32.853 1.00 56.71 ? 50 GLU B CD 1 ATOM 2527 O OE1 . GLU B 2 50 ? 56.213 17.984 -32.901 1.00 59.22 ? 50 GLU B OE1 1 ATOM 2528 O OE2 . GLU B 2 50 ? 58.372 17.917 -33.293 1.00 59.76 ? 50 GLU B OE2 1 ATOM 2529 N N . MET B 2 51 ? 55.971 21.492 -28.271 1.00 33.73 ? 51 MET B N 1 ATOM 2530 C CA . MET B 2 51 ? 55.338 21.442 -26.938 1.00 33.31 ? 51 MET B CA 1 ATOM 2531 C C . MET B 2 51 ? 54.076 20.601 -26.940 1.00 31.45 ? 51 MET B C 1 ATOM 2532 O O . MET B 2 51 ? 53.216 20.747 -27.796 1.00 32.88 ? 51 MET B O 1 ATOM 2533 C CB . MET B 2 51 ? 54.948 22.843 -26.453 1.00 35.31 ? 51 MET B CB 1 ATOM 2534 C CG . MET B 2 51 ? 56.092 23.840 -26.339 1.00 35.83 ? 51 MET B CG 1 ATOM 2535 S SD . MET B 2 51 ? 56.948 23.673 -24.777 1.00 36.00 ? 51 MET B SD 1 ATOM 2536 C CE . MET B 2 51 ? 58.488 24.519 -25.156 1.00 36.01 ? 51 MET B CE 1 ATOM 2537 N N . SER B 2 52 ? 53.946 19.728 -25.961 1.00 30.22 ? 52 SER B N 1 ATOM 2538 C CA . SER B 2 52 ? 52.700 19.012 -25.772 1.00 28.42 ? 52 SER B CA 1 ATOM 2539 C C . SER B 2 52 ? 51.682 20.013 -25.264 1.00 27.89 ? 52 SER B C 1 ATOM 2540 O O . SER B 2 52 ? 52.051 21.067 -24.756 1.00 29.06 ? 52 SER B O 1 ATOM 2541 C CB . SER B 2 52 ? 52.899 17.951 -24.713 1.00 28.19 ? 52 SER B CB 1 ATOM 2542 O OG . SER B 2 52 ? 53.187 18.568 -23.471 1.00 27.03 ? 52 SER B OG 1 ATOM 2543 N N . ASP B 2 53 ? 50.401 19.700 -25.379 1.00 27.29 ? 53 ASP B N 1 ATOM 2544 C CA . ASP B 2 53 ? 49.412 20.517 -24.692 1.00 26.60 ? 53 ASP B CA 1 ATOM 2545 C C . ASP B 2 53 ? 49.631 20.408 -23.193 1.00 26.46 ? 53 ASP B C 1 ATOM 2546 O O . ASP B 2 53 ? 49.934 19.338 -22.666 1.00 28.07 ? 53 ASP B O 1 ATOM 2547 C CB . ASP B 2 53 ? 48.016 20.046 -25.023 1.00 26.74 ? 53 ASP B CB 1 ATOM 2548 C CG . ASP B 2 53 ? 47.741 20.066 -26.492 1.00 27.30 ? 53 ASP B CG 1 ATOM 2549 O OD1 . ASP B 2 53 ? 48.081 21.078 -27.144 1.00 27.11 ? 53 ASP B OD1 1 ATOM 2550 O OD2 . ASP B 2 53 ? 47.170 19.071 -26.988 1.00 28.56 ? 53 ASP B OD2 1 ATOM 2551 N N . MET B 2 54 ? 49.496 21.516 -22.498 1.00 25.78 ? 54 MET B N 1 ATOM 2552 C CA . MET B 2 54 ? 49.502 21.463 -21.057 1.00 25.84 ? 54 MET B CA 1 ATOM 2553 C C . MET B 2 54 ? 48.310 20.661 -20.492 1.00 24.81 ? 54 MET B C 1 ATOM 2554 O O . MET B 2 54 ? 47.228 20.612 -21.085 1.00 25.37 ? 54 MET B O 1 ATOM 2555 C CB . MET B 2 54 ? 49.518 22.869 -20.499 1.00 26.89 ? 54 MET B CB 1 ATOM 2556 C CG . MET B 2 54 ? 49.738 22.908 -19.029 1.00 28.81 ? 54 MET B CG 1 ATOM 2557 S SD . MET B 2 54 ? 50.761 24.304 -18.650 1.00 31.93 ? 54 MET B SD 1 ATOM 2558 C CE . MET B 2 54 ? 49.694 24.985 -17.414 1.00 32.60 ? 54 MET B CE 1 ATOM 2559 N N . SER B 2 55 ? 48.531 20.043 -19.341 1.00 23.11 ? 55 SER B N 1 ATOM 2560 C CA . SER B 2 55 ? 47.569 19.156 -18.722 1.00 23.24 ? 55 SER B CA 1 ATOM 2561 C C . SER B 2 55 ? 47.866 19.180 -17.213 1.00 22.82 ? 55 SER B C 1 ATOM 2562 O O . SER B 2 55 ? 48.814 19.839 -16.792 1.00 22.80 ? 55 SER B O 1 ATOM 2563 C CB . SER B 2 55 ? 47.733 17.757 -19.337 1.00 24.11 ? 55 SER B CB 1 ATOM 2564 O OG . SER B 2 55 ? 46.784 16.823 -18.860 1.00 25.69 ? 55 SER B OG 1 ATOM 2565 N N . PHE B 2 56 ? 47.066 18.498 -16.394 1.00 22.07 ? 56 PHE B N 1 ATOM 2566 C CA . PHE B 2 56 ? 47.390 18.388 -14.975 1.00 22.59 ? 56 PHE B CA 1 ATOM 2567 C C . PHE B 2 56 ? 47.056 17.032 -14.383 1.00 24.52 ? 56 PHE B C 1 ATOM 2568 O O . PHE B 2 56 ? 46.201 16.318 -14.913 1.00 25.24 ? 56 PHE B O 1 ATOM 2569 C CB . PHE B 2 56 ? 46.726 19.504 -14.167 1.00 21.33 ? 56 PHE B CB 1 ATOM 2570 C CG . PHE B 2 56 ? 45.261 19.644 -14.406 1.00 20.13 ? 56 PHE B CG 1 ATOM 2571 C CD1 . PHE B 2 56 ? 44.349 18.886 -13.680 1.00 19.36 ? 56 PHE B CD1 1 ATOM 2572 C CD2 . PHE B 2 56 ? 44.786 20.562 -15.337 1.00 20.09 ? 56 PHE B CD2 1 ATOM 2573 C CE1 . PHE B 2 56 ? 42.998 19.020 -13.891 1.00 18.85 ? 56 PHE B CE1 1 ATOM 2574 C CE2 . PHE B 2 56 ? 43.414 20.703 -15.559 1.00 19.58 ? 56 PHE B CE2 1 ATOM 2575 C CZ . PHE B 2 56 ? 42.524 19.930 -14.831 1.00 19.16 ? 56 PHE B CZ 1 ATOM 2576 N N . SER B 2 57 ? 47.721 16.685 -13.278 1.00 26.26 ? 57 SER B N 1 ATOM 2577 C CA . SER B 2 57 ? 47.512 15.392 -12.606 1.00 27.97 ? 57 SER B CA 1 ATOM 2578 C C . SER B 2 57 ? 46.301 15.434 -11.674 1.00 28.65 ? 57 SER B C 1 ATOM 2579 O O . SER B 2 57 ? 45.681 16.493 -11.487 1.00 29.23 ? 57 SER B O 1 ATOM 2580 C CB . SER B 2 57 ? 48.745 14.997 -11.797 1.00 30.77 ? 57 SER B CB 1 ATOM 2581 O OG . SER B 2 57 ? 49.917 15.637 -12.289 1.00 36.17 ? 57 SER B OG 1 ATOM 2582 N N . LYS B 2 58 ? 45.979 14.283 -11.077 1.00 28.33 ? 58 LYS B N 1 ATOM 2583 C CA . LYS B 2 58 ? 44.856 14.169 -10.145 1.00 27.75 ? 58 LYS B CA 1 ATOM 2584 C C . LYS B 2 58 ? 45.011 15.120 -8.968 1.00 27.66 ? 58 LYS B C 1 ATOM 2585 O O . LYS B 2 58 ? 44.018 15.631 -8.471 1.00 27.21 ? 58 LYS B O 1 ATOM 2586 C CB . LYS B 2 58 ? 44.679 12.725 -9.664 1.00 27.67 ? 58 LYS B CB 1 ATOM 2587 N N . ASP B 2 59 ? 46.256 15.367 -8.554 1.00 28.36 ? 59 ASP B N 1 ATOM 2588 C CA . ASP B 2 59 ? 46.578 16.342 -7.497 1.00 29.56 ? 59 ASP B CA 1 ATOM 2589 C C . ASP B 2 59 ? 46.532 17.809 -7.958 1.00 28.95 ? 59 ASP B C 1 ATOM 2590 O O . ASP B 2 59 ? 47.051 18.687 -7.258 1.00 29.90 ? 59 ASP B O 1 ATOM 2591 C CB . ASP B 2 59 ? 47.941 16.023 -6.822 1.00 32.00 ? 59 ASP B CB 1 ATOM 2592 C CG . ASP B 2 59 ? 49.169 16.523 -7.637 1.00 36.65 ? 59 ASP B CG 1 ATOM 2593 O OD1 . ASP B 2 59 ? 49.023 16.884 -8.840 1.00 38.65 ? 59 ASP B OD1 1 ATOM 2594 O OD2 . ASP B 2 59 ? 50.292 16.552 -7.067 1.00 35.82 ? 59 ASP B OD2 1 ATOM 2595 N N . TRP B 2 60 ? 45.944 18.062 -9.132 1.00 26.60 ? 60 TRP B N 1 ATOM 2596 C CA . TRP B 2 60 ? 45.747 19.419 -9.684 1.00 25.41 ? 60 TRP B CA 1 ATOM 2597 C C . TRP B 2 60 ? 46.968 20.153 -10.147 1.00 25.79 ? 60 TRP B C 1 ATOM 2598 O O . TRP B 2 60 ? 46.853 21.272 -10.652 1.00 25.98 ? 60 TRP B O 1 ATOM 2599 C CB . TRP B 2 60 ? 44.956 20.298 -8.729 1.00 25.26 ? 60 TRP B CB 1 ATOM 2600 C CG . TRP B 2 60 ? 43.636 19.678 -8.376 1.00 25.77 ? 60 TRP B CG 1 ATOM 2601 C CD1 . TRP B 2 60 ? 43.300 19.005 -7.210 1.00 24.91 ? 60 TRP B CD1 1 ATOM 2602 C CD2 . TRP B 2 60 ? 42.434 19.609 -9.219 1.00 26.00 ? 60 TRP B CD2 1 ATOM 2603 N NE1 . TRP B 2 60 ? 42.012 18.565 -7.258 1.00 25.16 ? 60 TRP B NE1 1 ATOM 2604 C CE2 . TRP B 2 60 ? 41.434 18.882 -8.436 1.00 25.70 ? 60 TRP B CE2 1 ATOM 2605 C CE3 . TRP B 2 60 ? 42.095 20.075 -10.493 1.00 25.90 ? 60 TRP B CE3 1 ATOM 2606 C CZ2 . TRP B 2 60 ? 40.157 18.639 -8.921 1.00 25.79 ? 60 TRP B CZ2 1 ATOM 2607 C CZ3 . TRP B 2 60 ? 40.810 19.818 -10.972 1.00 25.92 ? 60 TRP B CZ3 1 ATOM 2608 C CH2 . TRP B 2 60 ? 39.864 19.120 -10.203 1.00 26.05 ? 60 TRP B CH2 1 ATOM 2609 N N . SER B 2 61 ? 48.148 19.555 -9.998 1.00 26.36 ? 61 SER B N 1 ATOM 2610 C CA . SER B 2 61 ? 49.378 20.226 -10.437 1.00 26.47 ? 61 SER B CA 1 ATOM 2611 C C . SER B 2 61 ? 49.570 20.075 -11.937 1.00 25.50 ? 61 SER B C 1 ATOM 2612 O O . SER B 2 61 ? 49.226 19.035 -12.515 1.00 24.73 ? 61 SER B O 1 ATOM 2613 C CB . SER B 2 61 ? 50.607 19.713 -9.667 1.00 27.48 ? 61 SER B CB 1 ATOM 2614 O OG . SER B 2 61 ? 50.830 18.334 -9.902 1.00 27.66 ? 61 SER B OG 1 ATOM 2615 N N . PHE B 2 62 ? 50.131 21.109 -12.557 1.00 25.28 ? 62 PHE B N 1 ATOM 2616 C CA . PHE B 2 62 ? 50.314 21.136 -14.009 1.00 25.31 ? 62 PHE B CA 1 ATOM 2617 C C . PHE B 2 62 ? 51.572 20.424 -14.484 1.00 26.21 ? 62 PHE B C 1 ATOM 2618 O O . PHE B 2 62 ? 52.552 20.327 -13.744 1.00 27.34 ? 62 PHE B O 1 ATOM 2619 C CB . PHE B 2 62 ? 50.307 22.571 -14.502 1.00 24.78 ? 62 PHE B CB 1 ATOM 2620 C CG . PHE B 2 62 ? 48.965 23.231 -14.396 1.00 25.53 ? 62 PHE B CG 1 ATOM 2621 C CD1 . PHE B 2 62 ? 48.656 24.046 -13.301 1.00 25.37 ? 62 PHE B CD1 1 ATOM 2622 C CD2 . PHE B 2 62 ? 47.991 23.033 -15.384 1.00 24.99 ? 62 PHE B CD2 1 ATOM 2623 C CE1 . PHE B 2 62 ? 47.400 24.657 -13.199 1.00 24.68 ? 62 PHE B CE1 1 ATOM 2624 C CE2 . PHE B 2 62 ? 46.743 23.651 -15.285 1.00 24.47 ? 62 PHE B CE2 1 ATOM 2625 C CZ . PHE B 2 62 ? 46.451 24.459 -14.196 1.00 23.92 ? 62 PHE B CZ 1 ATOM 2626 N N . TYR B 2 63 ? 51.538 19.922 -15.718 1.00 26.46 ? 63 TYR B N 1 ATOM 2627 C CA . TYR B 2 63 ? 52.717 19.312 -16.342 1.00 26.22 ? 63 TYR B CA 1 ATOM 2628 C C . TYR B 2 63 ? 52.762 19.562 -17.853 1.00 26.62 ? 63 TYR B C 1 ATOM 2629 O O . TYR B 2 63 ? 51.724 19.774 -18.490 1.00 27.50 ? 63 TYR B O 1 ATOM 2630 C CB . TYR B 2 63 ? 52.784 17.814 -16.041 1.00 26.03 ? 63 TYR B CB 1 ATOM 2631 C CG . TYR B 2 63 ? 51.666 16.993 -16.633 1.00 26.08 ? 63 TYR B CG 1 ATOM 2632 C CD1 . TYR B 2 63 ? 51.655 16.672 -17.989 1.00 26.78 ? 63 TYR B CD1 1 ATOM 2633 C CD2 . TYR B 2 63 ? 50.635 16.504 -15.833 1.00 26.45 ? 63 TYR B CD2 1 ATOM 2634 C CE1 . TYR B 2 63 ? 50.631 15.911 -18.547 1.00 27.01 ? 63 TYR B CE1 1 ATOM 2635 C CE2 . TYR B 2 63 ? 49.607 15.731 -16.377 1.00 26.93 ? 63 TYR B CE2 1 ATOM 2636 C CZ . TYR B 2 63 ? 49.613 15.441 -17.739 1.00 27.76 ? 63 TYR B CZ 1 ATOM 2637 O OH . TYR B 2 63 ? 48.600 14.690 -18.302 1.00 29.61 ? 63 TYR B OH 1 ATOM 2638 N N . ILE B 2 64 ? 53.958 19.543 -18.429 1.00 24.74 ? 64 ILE B N 1 ATOM 2639 C CA . ILE B 2 64 ? 54.089 19.746 -19.856 1.00 24.17 ? 64 ILE B CA 1 ATOM 2640 C C . ILE B 2 64 ? 55.386 19.135 -20.379 1.00 25.37 ? 64 ILE B C 1 ATOM 2641 O O . ILE B 2 64 ? 56.415 19.135 -19.682 1.00 25.33 ? 64 ILE B O 1 ATOM 2642 C CB . ILE B 2 64 ? 53.953 21.247 -20.246 1.00 23.94 ? 64 ILE B CB 1 ATOM 2643 C CG1 . ILE B 2 64 ? 53.823 21.414 -21.766 1.00 23.68 ? 64 ILE B CG1 1 ATOM 2644 C CG2 . ILE B 2 64 ? 55.105 22.081 -19.677 1.00 23.62 ? 64 ILE B CG2 1 ATOM 2645 C CD1 . ILE B 2 64 ? 53.354 22.777 -22.185 1.00 24.21 ? 64 ILE B CD1 1 ATOM 2646 N N . LEU B 2 65 ? 55.324 18.618 -21.605 1.00 25.40 ? 65 LEU B N 1 ATOM 2647 C CA . LEU B 2 65 ? 56.474 18.012 -22.241 1.00 27.00 ? 65 LEU B CA 1 ATOM 2648 C C . LEU B 2 65 ? 57.000 18.819 -23.435 1.00 28.69 ? 65 LEU B C 1 ATOM 2649 O O . LEU B 2 65 ? 56.270 19.092 -24.397 1.00 29.09 ? 65 LEU B O 1 ATOM 2650 C CB . LEU B 2 65 ? 56.160 16.572 -22.664 1.00 26.43 ? 65 LEU B CB 1 ATOM 2651 C CG . LEU B 2 65 ? 57.293 15.855 -23.397 1.00 26.38 ? 65 LEU B CG 1 ATOM 2652 C CD1 . LEU B 2 65 ? 58.497 15.695 -22.490 1.00 26.56 ? 65 LEU B CD1 1 ATOM 2653 C CD2 . LEU B 2 65 ? 56.825 14.524 -23.921 1.00 26.90 ? 65 LEU B CD2 1 ATOM 2654 N N . ALA B 2 66 ? 58.280 19.177 -23.365 1.00 29.79 ? 66 ALA B N 1 ATOM 2655 C CA . ALA B 2 66 ? 58.963 19.822 -24.477 1.00 30.74 ? 66 ALA B CA 1 ATOM 2656 C C . ALA B 2 66 ? 59.932 18.818 -25.013 1.00 32.15 ? 66 ALA B C 1 ATOM 2657 O O . ALA B 2 66 ? 60.515 18.055 -24.243 1.00 32.77 ? 66 ALA B O 1 ATOM 2658 C CB . ALA B 2 66 ? 59.709 21.058 -24.013 1.00 30.17 ? 66 ALA B CB 1 ATOM 2659 N N . HIS B 2 67 ? 60.099 18.806 -26.331 1.00 33.44 ? 67 HIS B N 1 ATOM 2660 C CA . HIS B 2 67 ? 61.076 17.934 -26.957 1.00 34.05 ? 67 HIS B CA 1 ATOM 2661 C C . HIS B 2 67 ? 61.567 18.531 -28.237 1.00 34.64 ? 67 HIS B C 1 ATOM 2662 O O . HIS B 2 67 ? 60.888 19.363 -28.853 1.00 34.62 ? 67 HIS B O 1 ATOM 2663 C CB . HIS B 2 67 ? 60.481 16.551 -27.212 1.00 36.07 ? 67 HIS B CB 1 ATOM 2664 C CG . HIS B 2 67 ? 59.465 16.520 -28.328 1.00 37.19 ? 67 HIS B CG 1 ATOM 2665 N ND1 . HIS B 2 67 ? 58.176 16.864 -28.143 1.00 38.92 ? 67 HIS B ND1 1 ATOM 2666 C CD2 . HIS B 2 67 ? 59.596 16.182 -29.675 1.00 37.49 ? 67 HIS B CD2 1 ATOM 2667 C CE1 . HIS B 2 67 ? 57.510 16.745 -29.310 1.00 38.63 ? 67 HIS B CE1 1 ATOM 2668 N NE2 . HIS B 2 67 ? 58.382 16.330 -30.246 1.00 39.12 ? 67 HIS B NE2 1 ATOM 2669 N N . THR B 2 68 ? 62.751 18.093 -28.647 1.00 33.96 ? 68 THR B N 1 ATOM 2670 C CA . THR B 2 68 ? 63.382 18.574 -29.856 1.00 34.58 ? 68 THR B CA 1 ATOM 2671 C C . THR B 2 68 ? 64.384 17.557 -30.410 1.00 35.53 ? 68 THR B C 1 ATOM 2672 O O . THR B 2 68 ? 64.933 16.736 -29.670 1.00 34.52 ? 68 THR B O 1 ATOM 2673 C CB . THR B 2 68 ? 64.081 19.935 -29.607 1.00 34.92 ? 68 THR B CB 1 ATOM 2674 O OG1 . THR B 2 68 ? 64.480 20.511 -30.859 1.00 36.93 ? 68 THR B OG1 1 ATOM 2675 C CG2 . THR B 2 68 ? 65.294 19.780 -28.693 1.00 33.61 ? 68 THR B CG2 1 ATOM 2676 N N . GLU B 2 69 ? 64.604 17.614 -31.720 1.00 38.41 ? 69 GLU B N 1 ATOM 2677 C CA . GLU B 2 69 ? 65.624 16.806 -32.379 1.00 40.01 ? 69 GLU B CA 1 ATOM 2678 C C . GLU B 2 69 ? 67.014 17.292 -32.018 1.00 39.15 ? 69 GLU B C 1 ATOM 2679 O O . GLU B 2 69 ? 67.308 18.476 -32.121 1.00 41.36 ? 69 GLU B O 1 ATOM 2680 C CB . GLU B 2 69 ? 65.445 16.840 -33.889 1.00 41.87 ? 69 GLU B CB 1 ATOM 2681 C CG . GLU B 2 69 ? 64.645 15.673 -34.399 1.00 48.85 ? 69 GLU B CG 1 ATOM 2682 C CD . GLU B 2 69 ? 63.859 16.000 -35.652 1.00 55.62 ? 69 GLU B CD 1 ATOM 2683 O OE1 . GLU B 2 69 ? 63.698 15.085 -36.499 1.00 58.76 ? 69 GLU B OE1 1 ATOM 2684 O OE2 . GLU B 2 69 ? 63.394 17.163 -35.785 1.00 58.20 ? 69 GLU B OE2 1 ATOM 2685 N N . PHE B 2 70 ? 67.864 16.380 -31.575 1.00 37.20 ? 70 PHE B N 1 ATOM 2686 C CA . PHE B 2 70 ? 69.236 16.737 -31.321 1.00 37.73 ? 70 PHE B CA 1 ATOM 2687 C C . PHE B 2 70 ? 70.188 15.628 -31.758 1.00 40.01 ? 70 PHE B C 1 ATOM 2688 O O . PHE B 2 70 ? 69.750 14.531 -32.099 1.00 39.38 ? 70 PHE B O 1 ATOM 2689 C CB . PHE B 2 70 ? 69.429 17.137 -29.855 1.00 34.81 ? 70 PHE B CB 1 ATOM 2690 C CG . PHE B 2 70 ? 69.664 15.986 -28.913 1.00 33.12 ? 70 PHE B CG 1 ATOM 2691 C CD1 . PHE B 2 70 ? 70.655 16.079 -27.935 1.00 32.58 ? 70 PHE B CD1 1 ATOM 2692 C CD2 . PHE B 2 70 ? 68.890 14.829 -28.972 1.00 31.54 ? 70 PHE B CD2 1 ATOM 2693 C CE1 . PHE B 2 70 ? 70.881 15.032 -27.037 1.00 31.49 ? 70 PHE B CE1 1 ATOM 2694 C CE2 . PHE B 2 70 ? 69.107 13.787 -28.079 1.00 30.50 ? 70 PHE B CE2 1 ATOM 2695 C CZ . PHE B 2 70 ? 70.103 13.884 -27.114 1.00 30.72 ? 70 PHE B CZ 1 ATOM 2696 N N . THR B 2 71 ? 71.483 15.950 -31.769 1.00 40.58 ? 71 THR B N 1 ATOM 2697 C CA . THR B 2 71 ? 72.540 14.993 -32.035 1.00 39.68 ? 71 THR B CA 1 ATOM 2698 C C . THR B 2 71 ? 73.618 15.141 -30.961 1.00 41.37 ? 71 THR B C 1 ATOM 2699 O O . THR B 2 71 ? 74.353 16.135 -30.942 1.00 41.94 ? 71 THR B O 1 ATOM 2700 C CB . THR B 2 71 ? 73.119 15.213 -33.421 1.00 38.25 ? 71 THR B CB 1 ATOM 2701 O OG1 . THR B 2 71 ? 72.068 15.067 -34.379 1.00 37.78 ? 71 THR B OG1 1 ATOM 2702 C CG2 . THR B 2 71 ? 74.211 14.200 -33.712 1.00 38.87 ? 71 THR B CG2 1 ATOM 2703 N N . PRO B 2 72 ? 73.699 14.164 -30.041 1.00 41.72 ? 72 PRO B N 1 ATOM 2704 C CA . PRO B 2 72 ? 74.683 14.271 -28.967 1.00 42.59 ? 72 PRO B CA 1 ATOM 2705 C C . PRO B 2 72 ? 76.110 14.100 -29.491 1.00 44.70 ? 72 PRO B C 1 ATOM 2706 O O . PRO B 2 72 ? 76.396 13.137 -30.197 1.00 47.67 ? 72 PRO B O 1 ATOM 2707 C CB . PRO B 2 72 ? 74.295 13.137 -28.010 1.00 40.94 ? 72 PRO B CB 1 ATOM 2708 C CG . PRO B 2 72 ? 73.534 12.169 -28.831 1.00 40.83 ? 72 PRO B CG 1 ATOM 2709 C CD . PRO B 2 72 ? 72.874 12.946 -29.932 1.00 40.67 ? 72 PRO B CD 1 ATOM 2710 N N . THR B 2 73 ? 76.979 15.059 -29.195 1.00 45.65 ? 73 THR B N 1 ATOM 2711 C CA . THR B 2 73 ? 78.394 14.931 -29.533 1.00 47.09 ? 73 THR B CA 1 ATOM 2712 C C . THR B 2 73 ? 79.184 14.978 -28.234 1.00 50.12 ? 73 THR B C 1 ATOM 2713 O O . THR B 2 73 ? 78.617 15.189 -27.159 1.00 48.68 ? 73 THR B O 1 ATOM 2714 C CB . THR B 2 73 ? 78.902 16.042 -30.499 1.00 45.92 ? 73 THR B CB 1 ATOM 2715 O OG1 . THR B 2 73 ? 79.172 17.245 -29.762 1.00 46.25 ? 73 THR B OG1 1 ATOM 2716 C CG2 . THR B 2 73 ? 77.899 16.323 -31.627 1.00 43.91 ? 73 THR B CG2 1 ATOM 2717 N N . GLU B 2 74 ? 80.490 14.780 -28.330 1.00 53.58 ? 74 GLU B N 1 ATOM 2718 C CA . GLU B 2 74 ? 81.327 14.807 -27.147 1.00 58.00 ? 74 GLU B CA 1 ATOM 2719 C C . GLU B 2 74 ? 81.398 16.209 -26.523 1.00 59.13 ? 74 GLU B C 1 ATOM 2720 O O . GLU B 2 74 ? 81.437 16.357 -25.299 1.00 57.46 ? 74 GLU B O 1 ATOM 2721 C CB . GLU B 2 74 ? 82.717 14.296 -27.496 1.00 61.69 ? 74 GLU B CB 1 ATOM 2722 C CG . GLU B 2 74 ? 83.473 13.718 -26.314 1.00 66.77 ? 74 GLU B CG 1 ATOM 2723 C CD . GLU B 2 74 ? 84.892 13.336 -26.677 1.00 69.92 ? 74 GLU B CD 1 ATOM 2724 O OE1 . GLU B 2 74 ? 85.098 12.802 -27.792 1.00 68.84 ? 74 GLU B OE1 1 ATOM 2725 O OE2 . GLU B 2 74 ? 85.799 13.572 -25.848 1.00 71.95 ? 74 GLU B OE2 1 ATOM 2726 N N . THR B 2 75 ? 81.386 17.230 -27.374 1.00 61.07 ? 75 THR B N 1 ATOM 2727 C CA . THR B 2 75 ? 81.602 18.606 -26.934 1.00 61.39 ? 75 THR B CA 1 ATOM 2728 C C . THR B 2 75 ? 80.336 19.333 -26.480 1.00 59.71 ? 75 THR B C 1 ATOM 2729 O O . THR B 2 75 ? 80.342 19.948 -25.415 1.00 62.63 ? 75 THR B O 1 ATOM 2730 C CB . THR B 2 75 ? 82.341 19.443 -28.010 1.00 63.66 ? 75 THR B CB 1 ATOM 2731 O OG1 . THR B 2 75 ? 81.988 18.970 -29.320 1.00 63.21 ? 75 THR B OG1 1 ATOM 2732 C CG2 . THR B 2 75 ? 83.859 19.336 -27.825 1.00 63.99 ? 75 THR B CG2 1 ATOM 2733 N N . ASP B 2 76 ? 79.268 19.248 -27.281 1.00 55.88 ? 76 ASP B N 1 ATOM 2734 C CA . ASP B 2 76 ? 78.006 19.994 -27.072 1.00 50.15 ? 76 ASP B CA 1 ATOM 2735 C C . ASP B 2 76 ? 77.256 19.726 -25.763 1.00 46.44 ? 76 ASP B C 1 ATOM 2736 O O . ASP B 2 76 ? 77.024 18.573 -25.408 1.00 46.67 ? 76 ASP B O 1 ATOM 2737 C CB . ASP B 2 76 ? 77.049 19.713 -28.224 1.00 50.36 ? 76 ASP B CB 1 ATOM 2738 C CG . ASP B 2 76 ? 77.509 20.317 -29.518 1.00 52.71 ? 76 ASP B CG 1 ATOM 2739 O OD1 . ASP B 2 76 ? 78.042 21.446 -29.483 1.00 54.08 ? 76 ASP B OD1 1 ATOM 2740 O OD2 . ASP B 2 76 ? 77.321 19.670 -30.575 1.00 53.63 ? 76 ASP B OD2 1 ATOM 2741 N N . THR B 2 77 ? 76.858 20.793 -25.068 1.00 41.84 ? 77 THR B N 1 ATOM 2742 C CA . THR B 2 77 ? 76.029 20.667 -23.863 1.00 39.87 ? 77 THR B CA 1 ATOM 2743 C C . THR B 2 77 ? 74.586 21.103 -24.113 1.00 36.96 ? 77 THR B C 1 ATOM 2744 O O . THR B 2 77 ? 74.337 22.097 -24.793 1.00 37.36 ? 77 THR B O 1 ATOM 2745 C CB . THR B 2 77 ? 76.599 21.443 -22.625 1.00 40.00 ? 77 THR B CB 1 ATOM 2746 O OG1 . THR B 2 77 ? 76.736 22.833 -22.938 1.00 39.83 ? 77 THR B OG1 1 ATOM 2747 C CG2 . THR B 2 77 ? 77.938 20.864 -22.154 1.00 37.34 ? 77 THR B CG2 1 ATOM 2748 N N . TYR B 2 78 ? 73.649 20.359 -23.533 1.00 34.96 ? 78 TYR B N 1 ATOM 2749 C CA . TYR B 2 78 ? 72.217 20.574 -23.732 1.00 34.50 ? 78 TYR B CA 1 ATOM 2750 C C . TYR B 2 78 ? 71.504 20.835 -22.418 1.00 34.98 ? 78 TYR B C 1 ATOM 2751 O O . TYR B 2 78 ? 71.774 20.177 -21.414 1.00 34.50 ? 78 TYR B O 1 ATOM 2752 C CB . TYR B 2 78 ? 71.593 19.359 -24.410 1.00 33.44 ? 78 TYR B CB 1 ATOM 2753 C CG . TYR B 2 78 ? 71.996 19.199 -25.855 1.00 34.60 ? 78 TYR B CG 1 ATOM 2754 C CD1 . TYR B 2 78 ? 73.110 18.430 -26.213 1.00 34.78 ? 78 TYR B CD1 1 ATOM 2755 C CD2 . TYR B 2 78 ? 71.264 19.822 -26.870 1.00 34.51 ? 78 TYR B CD2 1 ATOM 2756 C CE1 . TYR B 2 78 ? 73.484 18.290 -27.553 1.00 35.85 ? 78 TYR B CE1 1 ATOM 2757 C CE2 . TYR B 2 78 ? 71.620 19.688 -28.205 1.00 35.31 ? 78 TYR B CE2 1 ATOM 2758 C CZ . TYR B 2 78 ? 72.732 18.923 -28.544 1.00 36.60 ? 78 TYR B CZ 1 ATOM 2759 O OH . TYR B 2 78 ? 73.076 18.795 -29.875 1.00 37.11 ? 78 TYR B OH 1 ATOM 2760 N N . ALA B 2 79 ? 70.579 21.789 -22.424 1.00 36.32 ? 79 ALA B N 1 ATOM 2761 C CA . ALA B 2 79 ? 69.874 22.150 -21.193 1.00 36.58 ? 79 ALA B CA 1 ATOM 2762 C C . ALA B 2 79 ? 68.437 22.554 -21.432 1.00 36.32 ? 79 ALA B C 1 ATOM 2763 O O . ALA B 2 79 ? 68.023 22.808 -22.566 1.00 36.02 ? 79 ALA B O 1 ATOM 2764 C CB . ALA B 2 79 ? 70.620 23.262 -20.440 1.00 36.14 ? 79 ALA B CB 1 ATOM 2765 N N . CYS B 2 80 ? 67.684 22.591 -20.336 1.00 37.89 ? 80 CYS B N 1 ATOM 2766 C CA . CYS B 2 80 ? 66.300 23.047 -20.327 1.00 36.89 ? 80 CYS B CA 1 ATOM 2767 C C . CYS B 2 80 ? 66.179 24.101 -19.247 1.00 36.02 ? 80 CYS B C 1 ATOM 2768 O O . CYS B 2 80 ? 66.502 23.842 -18.085 1.00 34.46 ? 80 CYS B O 1 ATOM 2769 C CB . CYS B 2 80 ? 65.358 21.889 -20.044 1.00 37.04 ? 80 CYS B CB 1 ATOM 2770 S SG . CYS B 2 80 ? 63.625 22.268 -20.345 1.00 39.80 ? 80 CYS B SG 1 ATOM 2771 N N . ARG B 2 81 ? 65.751 25.293 -19.660 1.00 36.78 ? 81 ARG B N 1 ATOM 2772 C CA . ARG B 2 81 ? 65.708 26.476 -18.808 1.00 37.16 ? 81 ARG B CA 1 ATOM 2773 C C . ARG B 2 81 ? 64.258 26.883 -18.625 1.00 36.63 ? 81 ARG B C 1 ATOM 2774 O O . ARG B 2 81 ? 63.499 26.983 -19.597 1.00 36.98 ? 81 ARG B O 1 ATOM 2775 C CB . ARG B 2 81 ? 66.524 27.616 -19.437 1.00 39.86 ? 81 ARG B CB 1 ATOM 2776 C CG . ARG B 2 81 ? 66.520 28.955 -18.665 1.00 43.04 ? 81 ARG B CG 1 ATOM 2777 C CD . ARG B 2 81 ? 67.632 29.893 -19.150 1.00 45.27 ? 81 ARG B CD 1 ATOM 2778 N NE . ARG B 2 81 ? 68.944 29.476 -18.630 1.00 49.78 ? 81 ARG B NE 1 ATOM 2779 C CZ . ARG B 2 81 ? 70.131 29.852 -19.114 1.00 47.16 ? 81 ARG B CZ 1 ATOM 2780 N NH1 . ARG B 2 81 ? 70.224 30.661 -20.167 1.00 46.25 ? 81 ARG B NH1 1 ATOM 2781 N NH2 . ARG B 2 81 ? 71.236 29.400 -18.540 1.00 45.97 ? 81 ARG B NH2 1 ATOM 2782 N N . VAL B 2 82 ? 63.881 27.109 -17.373 1.00 35.33 ? 82 VAL B N 1 ATOM 2783 C CA . VAL B 2 82 ? 62.492 27.366 -17.020 1.00 36.69 ? 82 VAL B CA 1 ATOM 2784 C C . VAL B 2 82 ? 62.354 28.644 -16.201 1.00 37.49 ? 82 VAL B C 1 ATOM 2785 O O . VAL B 2 82 ? 63.069 28.835 -15.211 1.00 36.30 ? 82 VAL B O 1 ATOM 2786 C CB . VAL B 2 82 ? 61.877 26.166 -16.229 1.00 36.01 ? 82 VAL B CB 1 ATOM 2787 C CG1 . VAL B 2 82 ? 60.523 26.536 -15.640 1.00 35.86 ? 82 VAL B CG1 1 ATOM 2788 C CG2 . VAL B 2 82 ? 61.750 24.927 -17.115 1.00 34.48 ? 82 VAL B CG2 1 ATOM 2789 N N . LYS B 2 83 ? 61.431 29.513 -16.623 1.00 40.07 ? 83 LYS B N 1 ATOM 2790 C CA . LYS B 2 83 ? 61.040 30.698 -15.835 1.00 40.97 ? 83 LYS B CA 1 ATOM 2791 C C . LYS B 2 83 ? 59.605 30.536 -15.311 1.00 40.07 ? 83 LYS B C 1 ATOM 2792 O O . LYS B 2 83 ? 58.691 30.169 -16.061 1.00 39.00 ? 83 LYS B O 1 ATOM 2793 C CB . LYS B 2 83 ? 61.214 32.005 -16.638 1.00 38.39 ? 83 LYS B CB 1 ATOM 2794 N N . HIS B 2 84 ? 59.432 30.787 -14.017 1.00 39.79 ? 84 HIS B N 1 ATOM 2795 C CA . HIS B 2 84 ? 58.136 30.654 -13.352 1.00 42.36 ? 84 HIS B CA 1 ATOM 2796 C C . HIS B 2 84 ? 58.091 31.492 -12.106 1.00 44.13 ? 84 HIS B C 1 ATOM 2797 O O . HIS B 2 84 ? 59.064 31.533 -11.336 1.00 45.95 ? 84 HIS B O 1 ATOM 2798 C CB . HIS B 2 84 ? 57.855 29.194 -13.008 1.00 41.40 ? 84 HIS B CB 1 ATOM 2799 C CG . HIS B 2 84 ? 56.449 28.934 -12.522 1.00 41.20 ? 84 HIS B CG 1 ATOM 2800 N ND1 . HIS B 2 84 ? 56.183 28.485 -11.284 1.00 42.02 ? 84 HIS B ND1 1 ATOM 2801 C CD2 . HIS B 2 84 ? 55.221 29.066 -13.163 1.00 41.31 ? 84 HIS B CD2 1 ATOM 2802 C CE1 . HIS B 2 84 ? 54.852 28.339 -11.135 1.00 41.72 ? 84 HIS B CE1 1 ATOM 2803 N NE2 . HIS B 2 84 ? 54.265 28.697 -12.286 1.00 41.88 ? 84 HIS B NE2 1 ATOM 2804 N N . ALA B 2 85 ? 56.948 32.142 -11.891 1.00 43.96 ? 85 ALA B N 1 ATOM 2805 C CA . ALA B 2 85 ? 56.754 33.089 -10.790 1.00 44.19 ? 85 ALA B CA 1 ATOM 2806 C C . ALA B 2 85 ? 57.252 32.573 -9.433 1.00 45.95 ? 85 ALA B C 1 ATOM 2807 O O . ALA B 2 85 ? 57.777 33.343 -8.620 1.00 46.05 ? 85 ALA B O 1 ATOM 2808 C CB . ALA B 2 85 ? 55.296 33.513 -10.710 1.00 41.79 ? 85 ALA B CB 1 ATOM 2809 N N . SER B 2 86 ? 57.122 31.267 -9.213 1.00 46.66 ? 86 SER B N 1 ATOM 2810 C CA . SER B 2 86 ? 57.542 30.638 -7.959 1.00 46.84 ? 86 SER B CA 1 ATOM 2811 C C . SER B 2 86 ? 59.049 30.695 -7.732 1.00 46.85 ? 86 SER B C 1 ATOM 2812 O O . SER B 2 86 ? 59.545 30.206 -6.711 1.00 46.65 ? 86 SER B O 1 ATOM 2813 C CB . SER B 2 86 ? 57.104 29.175 -7.927 1.00 46.65 ? 86 SER B CB 1 ATOM 2814 O OG . SER B 2 86 ? 58.026 28.372 -8.643 1.00 47.04 ? 86 SER B OG 1 ATOM 2815 N N . MET B 2 87 ? 59.776 31.262 -8.690 1.00 46.62 ? 87 MET B N 1 ATOM 2816 C CA . MET B 2 87 ? 61.231 31.282 -8.618 1.00 48.15 ? 87 MET B CA 1 ATOM 2817 C C . MET B 2 87 ? 61.790 32.687 -8.804 1.00 50.16 ? 87 MET B C 1 ATOM 2818 O O . MET B 2 87 ? 61.421 33.397 -9.745 1.00 49.44 ? 87 MET B O 1 ATOM 2819 C CB . MET B 2 87 ? 61.836 30.324 -9.645 1.00 47.64 ? 87 MET B CB 1 ATOM 2820 C CG . MET B 2 87 ? 61.451 28.864 -9.435 1.00 49.10 ? 87 MET B CG 1 ATOM 2821 S SD . MET B 2 87 ? 62.274 27.670 -10.512 1.00 51.68 ? 87 MET B SD 1 ATOM 2822 C CE . MET B 2 87 ? 62.029 28.345 -12.155 1.00 47.08 ? 87 MET B CE 1 ATOM 2823 N N . ALA B 2 88 ? 62.670 33.086 -7.888 1.00 50.88 ? 88 ALA B N 1 ATOM 2824 C CA . ALA B 2 88 ? 63.384 34.346 -8.017 1.00 51.94 ? 88 ALA B CA 1 ATOM 2825 C C . ALA B 2 88 ? 64.205 34.309 -9.304 1.00 52.11 ? 88 ALA B C 1 ATOM 2826 O O . ALA B 2 88 ? 64.101 35.202 -10.155 1.00 48.48 ? 88 ALA B O 1 ATOM 2827 C CB . ALA B 2 88 ? 64.279 34.568 -6.810 1.00 51.40 ? 88 ALA B CB 1 ATOM 2828 N N . GLU B 2 89 ? 64.995 33.244 -9.437 1.00 55.28 ? 89 GLU B N 1 ATOM 2829 C CA . GLU B 2 89 ? 65.865 33.020 -10.593 1.00 55.02 ? 89 GLU B CA 1 ATOM 2830 C C . GLU B 2 89 ? 65.290 31.946 -11.514 1.00 49.12 ? 89 GLU B C 1 ATOM 2831 O O . GLU B 2 89 ? 64.581 31.057 -11.047 1.00 46.94 ? 89 GLU B O 1 ATOM 2832 C CB . GLU B 2 89 ? 67.271 32.607 -10.123 1.00 59.37 ? 89 GLU B CB 1 ATOM 2833 C CG . GLU B 2 89 ? 68.255 33.766 -9.991 1.00 65.39 ? 89 GLU B CG 1 ATOM 2834 C CD . GLU B 2 89 ? 68.587 34.405 -11.338 1.00 70.46 ? 89 GLU B CD 1 ATOM 2835 O OE1 . GLU B 2 89 ? 68.063 35.508 -11.622 1.00 68.21 ? 89 GLU B OE1 1 ATOM 2836 O OE2 . GLU B 2 89 ? 69.359 33.795 -12.119 1.00 74.46 ? 89 GLU B OE2 1 ATOM 2837 N N . PRO B 2 90 ? 65.577 32.041 -12.825 1.00 44.54 ? 90 PRO B N 1 ATOM 2838 C CA . PRO B 2 90 ? 65.287 30.966 -13.778 1.00 43.89 ? 90 PRO B CA 1 ATOM 2839 C C . PRO B 2 90 ? 66.141 29.717 -13.524 1.00 43.52 ? 90 PRO B C 1 ATOM 2840 O O . PRO B 2 90 ? 67.333 29.836 -13.231 1.00 46.69 ? 90 PRO B O 1 ATOM 2841 C CB . PRO B 2 90 ? 65.641 31.597 -15.122 1.00 43.31 ? 90 PRO B CB 1 ATOM 2842 C CG . PRO B 2 90 ? 65.434 33.057 -14.897 1.00 42.87 ? 90 PRO B CG 1 ATOM 2843 C CD . PRO B 2 90 ? 65.942 33.287 -13.516 1.00 43.55 ? 90 PRO B CD 1 ATOM 2844 N N . LYS B 2 91 ? 65.532 28.535 -13.616 1.00 40.56 ? 91 LYS B N 1 ATOM 2845 C CA . LYS B 2 91 ? 66.228 27.290 -13.297 1.00 39.04 ? 91 LYS B CA 1 ATOM 2846 C C . LYS B 2 91 ? 66.640 26.541 -14.550 1.00 37.59 ? 91 LYS B C 1 ATOM 2847 O O . LYS B 2 91 ? 65.819 26.260 -15.422 1.00 36.92 ? 91 LYS B O 1 ATOM 2848 C CB . LYS B 2 91 ? 65.384 26.373 -12.400 1.00 38.73 ? 91 LYS B CB 1 ATOM 2849 C CG . LYS B 2 91 ? 66.209 25.279 -11.713 1.00 40.14 ? 91 LYS B CG 1 ATOM 2850 C CD . LYS B 2 91 ? 65.415 23.997 -11.462 1.00 43.16 ? 91 LYS B CD 1 ATOM 2851 C CE . LYS B 2 91 ? 64.546 24.051 -10.197 1.00 44.27 ? 91 LYS B CE 1 ATOM 2852 N NZ . LYS B 2 91 ? 63.994 22.691 -9.856 1.00 43.83 ? 91 LYS B NZ 1 ATOM 2853 N N . THR B 2 92 ? 67.921 26.207 -14.616 1.00 38.21 ? 92 THR B N 1 ATOM 2854 C CA . THR B 2 92 ? 68.475 25.466 -15.735 1.00 37.79 ? 92 THR B CA 1 ATOM 2855 C C . THR B 2 92 ? 68.904 24.075 -15.274 1.00 38.48 ? 92 THR B C 1 ATOM 2856 O O . THR B 2 92 ? 69.659 23.949 -14.313 1.00 39.41 ? 92 THR B O 1 ATOM 2857 C CB . THR B 2 92 ? 69.666 26.216 -16.344 1.00 37.81 ? 92 THR B CB 1 ATOM 2858 O OG1 . THR B 2 92 ? 69.286 27.569 -16.637 1.00 38.13 ? 92 THR B OG1 1 ATOM 2859 C CG2 . THR B 2 92 ? 70.116 25.545 -17.623 1.00 39.67 ? 92 THR B CG2 1 ATOM 2860 N N . VAL B 2 93 ? 68.398 23.034 -15.937 1.00 37.46 ? 93 VAL B N 1 ATOM 2861 C CA . VAL B 2 93 ? 68.856 21.670 -15.686 1.00 36.07 ? 93 VAL B CA 1 ATOM 2862 C C . VAL B 2 93 ? 69.574 21.183 -16.943 1.00 37.78 ? 93 VAL B C 1 ATOM 2863 O O . VAL B 2 93 ? 69.096 21.389 -18.061 1.00 38.75 ? 93 VAL B O 1 ATOM 2864 C CB . VAL B 2 93 ? 67.696 20.725 -15.274 1.00 34.85 ? 93 VAL B CB 1 ATOM 2865 C CG1 . VAL B 2 93 ? 68.097 19.279 -15.407 1.00 34.87 ? 93 VAL B CG1 1 ATOM 2866 C CG2 . VAL B 2 93 ? 67.252 20.999 -13.847 1.00 34.09 ? 93 VAL B CG2 1 ATOM 2867 N N . TYR B 2 94 ? 70.733 20.563 -16.755 1.00 39.69 ? 94 TYR B N 1 ATOM 2868 C CA . TYR B 2 94 ? 71.552 20.107 -17.876 1.00 40.56 ? 94 TYR B CA 1 ATOM 2869 C C . TYR B 2 94 ? 71.297 18.652 -18.190 1.00 40.67 ? 94 TYR B C 1 ATOM 2870 O O . TYR B 2 94 ? 70.980 17.861 -17.309 1.00 39.52 ? 94 TYR B O 1 ATOM 2871 C CB . TYR B 2 94 ? 73.047 20.331 -17.601 1.00 40.50 ? 94 TYR B CB 1 ATOM 2872 C CG . TYR B 2 94 ? 73.461 21.769 -17.775 1.00 42.44 ? 94 TYR B CG 1 ATOM 2873 C CD1 . TYR B 2 94 ? 73.517 22.637 -16.678 1.00 43.44 ? 94 TYR B CD1 1 ATOM 2874 C CD2 . TYR B 2 94 ? 73.765 22.279 -19.044 1.00 43.28 ? 94 TYR B CD2 1 ATOM 2875 C CE1 . TYR B 2 94 ? 73.880 23.983 -16.835 1.00 44.70 ? 94 TYR B CE1 1 ATOM 2876 C CE2 . TYR B 2 94 ? 74.128 23.618 -19.214 1.00 45.14 ? 94 TYR B CE2 1 ATOM 2877 C CZ . TYR B 2 94 ? 74.185 24.463 -18.104 1.00 45.29 ? 94 TYR B CZ 1 ATOM 2878 O OH . TYR B 2 94 ? 74.546 25.781 -18.265 1.00 46.43 ? 94 TYR B OH 1 ATOM 2879 N N . TRP B 2 95 ? 71.425 18.309 -19.463 1.00 41.98 ? 95 TRP B N 1 ATOM 2880 C CA . TRP B 2 95 ? 71.406 16.925 -19.862 1.00 42.64 ? 95 TRP B CA 1 ATOM 2881 C C . TRP B 2 95 ? 72.706 16.299 -19.499 1.00 44.57 ? 95 TRP B C 1 ATOM 2882 O O . TRP B 2 95 ? 73.761 16.755 -19.919 1.00 46.89 ? 95 TRP B O 1 ATOM 2883 C CB . TRP B 2 95 ? 71.171 16.778 -21.355 1.00 41.48 ? 95 TRP B CB 1 ATOM 2884 C CG . TRP B 2 95 ? 71.097 15.333 -21.784 1.00 41.26 ? 95 TRP B CG 1 ATOM 2885 C CD1 . TRP B 2 95 ? 70.277 14.338 -21.264 1.00 40.27 ? 95 TRP B CD1 1 ATOM 2886 C CD2 . TRP B 2 95 ? 71.862 14.675 -22.851 1.00 40.74 ? 95 TRP B CD2 1 ATOM 2887 N NE1 . TRP B 2 95 ? 70.481 13.152 -21.908 1.00 40.93 ? 95 TRP B NE1 1 ATOM 2888 C CE2 . TRP B 2 95 ? 71.415 13.281 -22.871 1.00 41.77 ? 95 TRP B CE2 1 ATOM 2889 C CE3 . TRP B 2 95 ? 72.834 15.085 -23.753 1.00 39.80 ? 95 TRP B CE3 1 ATOM 2890 C CZ2 . TRP B 2 95 ? 71.937 12.351 -23.765 1.00 42.76 ? 95 TRP B CZ2 1 ATOM 2891 C CZ3 . TRP B 2 95 ? 73.354 14.144 -24.646 1.00 40.80 ? 95 TRP B CZ3 1 ATOM 2892 C CH2 . TRP B 2 95 ? 72.916 12.809 -24.653 1.00 42.10 ? 95 TRP B CH2 1 ATOM 2893 N N . ASP B 2 96 ? 72.623 15.263 -18.680 1.00 48.48 ? 96 ASP B N 1 ATOM 2894 C CA . ASP B 2 96 ? 73.730 14.381 -18.407 1.00 50.24 ? 96 ASP B CA 1 ATOM 2895 C C . ASP B 2 96 ? 73.335 13.019 -18.970 1.00 52.34 ? 96 ASP B C 1 ATOM 2896 O O . ASP B 2 96 ? 72.363 12.421 -18.504 1.00 51.97 ? 96 ASP B O 1 ATOM 2897 C CB . ASP B 2 96 ? 73.969 14.297 -16.900 1.00 49.82 ? 96 ASP B CB 1 ATOM 2898 C CG . ASP B 2 96 ? 75.177 13.452 -16.542 1.00 52.81 ? 96 ASP B CG 1 ATOM 2899 O OD1 . ASP B 2 96 ? 75.628 12.642 -17.390 1.00 51.48 ? 96 ASP B OD1 1 ATOM 2900 O OD2 . ASP B 2 96 ? 75.675 13.593 -15.400 1.00 55.14 ? 96 ASP B OD2 1 ATOM 2901 N N . ARG B 2 97 ? 74.083 12.545 -19.970 1.00 53.54 ? 97 ARG B N 1 ATOM 2902 C CA . ARG B 2 97 ? 73.828 11.247 -20.619 1.00 56.33 ? 97 ARG B CA 1 ATOM 2903 C C . ARG B 2 97 ? 73.812 10.055 -19.650 1.00 59.22 ? 97 ARG B C 1 ATOM 2904 O O . ARG B 2 97 ? 73.095 9.068 -19.867 1.00 56.48 ? 97 ARG B O 1 ATOM 2905 C CB . ARG B 2 97 ? 74.845 10.994 -21.740 1.00 58.39 ? 97 ARG B CB 1 ATOM 2906 C CG . ARG B 2 97 ? 76.315 11.115 -21.319 1.00 61.17 ? 97 ARG B CG 1 ATOM 2907 C CD . ARG B 2 97 ? 77.280 10.935 -22.496 1.00 61.39 ? 97 ARG B CD 1 ATOM 2908 N NE . ARG B 2 97 ? 77.245 12.071 -23.421 1.00 62.49 ? 97 ARG B NE 1 ATOM 2909 C CZ . ARG B 2 97 ? 76.921 11.999 -24.713 1.00 62.05 ? 97 ARG B CZ 1 ATOM 2910 N NH1 . ARG B 2 97 ? 76.613 10.836 -25.281 1.00 59.41 ? 97 ARG B NH1 1 ATOM 2911 N NH2 . ARG B 2 97 ? 76.923 13.102 -25.450 1.00 61.54 ? 97 ARG B NH2 1 ATOM 2912 N N . ASP B 2 98 ? 74.596 10.168 -18.580 1.00 62.79 ? 98 ASP B N 1 ATOM 2913 C CA . ASP B 2 98 ? 74.770 9.096 -17.605 1.00 65.20 ? 98 ASP B CA 1 ATOM 2914 C C . ASP B 2 98 ? 73.680 9.076 -16.532 1.00 68.95 ? 98 ASP B C 1 ATOM 2915 O O . ASP B 2 98 ? 73.391 8.020 -15.958 1.00 68.44 ? 98 ASP B O 1 ATOM 2916 C CB . ASP B 2 98 ? 76.136 9.215 -16.924 1.00 64.86 ? 98 ASP B CB 1 ATOM 2917 C CG . ASP B 2 98 ? 77.246 9.570 -17.886 1.00 63.90 ? 98 ASP B CG 1 ATOM 2918 O OD1 . ASP B 2 98 ? 77.274 9.019 -19.003 1.00 65.53 ? 98 ASP B OD1 1 ATOM 2919 O OD2 . ASP B 2 98 ? 78.100 10.400 -17.516 1.00 63.11 ? 98 ASP B OD2 1 ATOM 2920 N N . MET B 2 99 ? 73.094 10.244 -16.259 1.00 72.87 ? 99 MET B N 1 ATOM 2921 C CA . MET B 2 99 ? 72.109 10.402 -15.184 1.00 74.67 ? 99 MET B CA 1 ATOM 2922 C C . MET B 2 99 ? 70.671 10.342 -15.701 1.00 73.45 ? 99 MET B C 1 ATOM 2923 O O . MET B 2 99 ? 70.101 9.260 -15.855 1.00 73.92 ? 99 MET B O 1 ATOM 2924 C CB . MET B 2 99 ? 72.356 11.707 -14.416 1.00 74.00 ? 99 MET B CB 1 ATOM 2925 C CG . MET B 2 99 ? 71.762 11.719 -13.015 1.00 77.30 ? 99 MET B CG 1 ATOM 2926 S SD . MET B 2 99 ? 72.482 13.015 -11.987 1.00 82.88 ? 99 MET B SD 1 ATOM 2927 C CE . MET B 2 99 ? 71.545 12.825 -10.464 1.00 79.24 ? 99 MET B CE 1 ATOM 2928 N N . THR C 3 3 ? 21.897 45.189 -31.586 1.00 57.62 ? 1 THR C N 1 ATOM 2929 C CA . THR C 3 3 ? 20.518 44.811 -31.139 1.00 54.95 ? 1 THR C CA 1 ATOM 2930 C C . THR C 3 3 ? 20.180 43.387 -31.604 1.00 51.31 ? 1 THR C C 1 ATOM 2931 O O . THR C 3 3 ? 20.020 43.122 -32.804 1.00 47.71 ? 1 THR C O 1 ATOM 2932 C CB . THR C 3 3 ? 19.436 45.825 -31.623 1.00 55.38 ? 1 THR C CB 1 ATOM 2933 O OG1 . THR C 3 3 ? 19.095 45.560 -32.990 1.00 53.89 ? 1 THR C OG1 1 ATOM 2934 C CG2 . THR C 3 3 ? 19.936 47.285 -31.481 1.00 54.70 ? 1 THR C CG2 1 ATOM 2935 N N . GLN C 3 4 ? 20.070 42.490 -30.628 1.00 46.76 ? 2 GLN C N 1 ATOM 2936 C CA . GLN C 3 4 ? 19.893 41.060 -30.862 1.00 41.49 ? 2 GLN C CA 1 ATOM 2937 C C . GLN C 3 4 ? 18.444 40.591 -30.688 1.00 37.62 ? 2 GLN C C 1 ATOM 2938 O O . GLN C 3 4 ? 18.161 39.392 -30.752 1.00 35.62 ? 2 GLN C O 1 ATOM 2939 C CB . GLN C 3 4 ? 20.791 40.277 -29.904 1.00 43.29 ? 2 GLN C CB 1 ATOM 2940 C CG . GLN C 3 4 ? 22.214 40.811 -29.772 1.00 45.20 ? 2 GLN C CG 1 ATOM 2941 C CD . GLN C 3 4 ? 22.905 40.274 -28.538 1.00 46.96 ? 2 GLN C CD 1 ATOM 2942 O OE1 . GLN C 3 4 ? 23.169 39.075 -28.436 1.00 49.00 ? 2 GLN C OE1 1 ATOM 2943 N NE2 . GLN C 3 4 ? 23.194 41.159 -27.584 1.00 46.94 ? 2 GLN C NE2 1 ATOM 2944 N N . VAL C 3 5 ? 17.536 41.533 -30.454 1.00 34.07 ? 3 VAL C N 1 ATOM 2945 C CA . VAL C 3 5 ? 16.123 41.217 -30.267 1.00 33.55 ? 3 VAL C CA 1 ATOM 2946 C C . VAL C 3 5 ? 15.258 42.159 -31.121 1.00 33.47 ? 3 VAL C C 1 ATOM 2947 O O . VAL C 3 5 ? 15.172 43.357 -30.840 1.00 34.23 ? 3 VAL C O 1 ATOM 2948 C CB . VAL C 3 5 ? 15.708 41.278 -28.762 1.00 31.17 ? 3 VAL C CB 1 ATOM 2949 C CG1 . VAL C 3 5 ? 14.226 40.986 -28.594 1.00 31.52 ? 3 VAL C CG1 1 ATOM 2950 C CG2 . VAL C 3 5 ? 16.499 40.300 -27.949 1.00 29.22 ? 3 VAL C CG2 1 ATOM 2951 N N . GLU C 3 6 ? 14.625 41.613 -32.156 1.00 33.16 ? 4 GLU C N 1 ATOM 2952 C CA . GLU C 3 6 ? 13.833 42.416 -33.092 1.00 34.16 ? 4 GLU C CA 1 ATOM 2953 C C . GLU C 3 6 ? 12.351 42.045 -33.065 1.00 31.89 ? 4 GLU C C 1 ATOM 2954 O O . GLU C 3 6 ? 11.993 40.874 -33.181 1.00 31.66 ? 4 GLU C O 1 ATOM 2955 C CB . GLU C 3 6 ? 14.380 42.299 -34.515 1.00 39.17 ? 4 GLU C CB 1 ATOM 2956 C CG . GLU C 3 6 ? 15.846 42.711 -34.669 1.00 47.26 ? 4 GLU C CG 1 ATOM 2957 C CD . GLU C 3 6 ? 16.104 44.160 -34.245 1.00 54.03 ? 4 GLU C CD 1 ATOM 2958 O OE1 . GLU C 3 6 ? 15.653 45.081 -34.968 1.00 56.92 ? 4 GLU C OE1 1 ATOM 2959 O OE2 . GLU C 3 6 ? 16.758 44.377 -33.190 1.00 57.29 ? 4 GLU C OE2 1 ATOM 2960 N N . GLN C 3 7 ? 11.501 43.056 -32.901 1.00 29.12 ? 5 GLN C N 1 ATOM 2961 C CA . GLN C 3 7 ? 10.059 42.871 -32.876 1.00 27.26 ? 5 GLN C CA 1 ATOM 2962 C C . GLN C 3 7 ? 9.373 43.389 -34.134 1.00 26.37 ? 5 GLN C C 1 ATOM 2963 O O . GLN C 3 7 ? 9.833 44.323 -34.789 1.00 25.91 ? 5 GLN C O 1 ATOM 2964 C CB . GLN C 3 7 ? 9.448 43.527 -31.646 1.00 26.94 ? 5 GLN C CB 1 ATOM 2965 C CG . GLN C 3 7 ? 9.795 42.818 -30.359 1.00 27.62 ? 5 GLN C CG 1 ATOM 2966 C CD . GLN C 3 7 ? 9.201 43.497 -29.147 1.00 27.37 ? 5 GLN C CD 1 ATOM 2967 O OE1 . GLN C 3 7 ? 9.917 43.946 -28.256 1.00 28.06 ? 5 GLN C OE1 1 ATOM 2968 N NE2 . GLN C 3 7 ? 7.887 43.585 -29.112 1.00 27.30 ? 5 GLN C NE2 1 ATOM 2969 N N . SER C 3 8 ? 8.253 42.758 -34.449 1.00 26.53 ? 6 SER C N 1 ATOM 2970 C CA . SER C 3 8 ? 7.480 43.042 -35.639 1.00 26.12 ? 6 SER C CA 1 ATOM 2971 C C . SER C 3 8 ? 6.027 42.729 -35.309 1.00 26.17 ? 6 SER C C 1 ATOM 2972 O O . SER C 3 8 ? 5.752 41.735 -34.627 1.00 27.37 ? 6 SER C O 1 ATOM 2973 C CB . SER C 3 8 ? 7.952 42.144 -36.776 1.00 26.62 ? 6 SER C CB 1 ATOM 2974 O OG . SER C 3 8 ? 7.464 42.598 -38.018 1.00 27.50 ? 6 SER C OG 1 ATOM 2975 N N . PRO C 3 9 ? 5.089 43.571 -35.770 1.00 25.34 ? 7 PRO C N 1 ATOM 2976 C CA . PRO C 3 9 ? 5.320 44.803 -36.519 1.00 25.81 ? 7 PRO C CA 1 ATOM 2977 C C . PRO C 3 9 ? 5.838 45.899 -35.599 1.00 26.59 ? 7 PRO C C 1 ATOM 2978 O O . PRO C 3 9 ? 5.830 45.730 -34.379 1.00 26.59 ? 7 PRO C O 1 ATOM 2979 C CB . PRO C 3 9 ? 3.921 45.166 -37.030 1.00 25.58 ? 7 PRO C CB 1 ATOM 2980 C CG . PRO C 3 9 ? 3.086 43.922 -36.818 1.00 24.59 ? 7 PRO C CG 1 ATOM 2981 C CD . PRO C 3 9 ? 3.655 43.274 -35.639 1.00 24.09 ? 7 PRO C CD 1 ATOM 2982 N N . GLN C 3 10 ? 6.308 46.994 -36.183 1.00 27.78 ? 8 GLN C N 1 ATOM 2983 C CA . GLN C 3 10 ? 6.684 48.174 -35.427 1.00 30.04 ? 8 GLN C CA 1 ATOM 2984 C C . GLN C 3 10 ? 5.451 48.718 -34.697 1.00 28.62 ? 8 GLN C C 1 ATOM 2985 O O . GLN C 3 10 ? 5.498 48.964 -33.494 1.00 28.17 ? 8 GLN C O 1 ATOM 2986 C CB . GLN C 3 10 ? 7.277 49.224 -36.371 1.00 35.40 ? 8 GLN C CB 1 ATOM 2987 C CG . GLN C 3 10 ? 7.561 50.594 -35.737 1.00 41.30 ? 8 GLN C CG 1 ATOM 2988 C CD . GLN C 3 10 ? 8.509 51.455 -36.582 1.00 45.03 ? 8 GLN C CD 1 ATOM 2989 O OE1 . GLN C 3 10 ? 9.666 51.080 -36.809 1.00 49.03 ? 8 GLN C OE1 1 ATOM 2990 N NE2 . GLN C 3 10 ? 8.020 52.612 -37.047 1.00 44.20 ? 8 GLN C NE2 1 ATOM 2991 N N . SER C 3 11 ? 4.352 48.893 -35.430 1.00 27.40 ? 9 SER C N 1 ATOM 2992 C CA . SER C 3 11 ? 3.074 49.300 -34.850 1.00 25.53 ? 9 SER C CA 1 ATOM 2993 C C . SER C 3 11 ? 1.898 48.781 -35.677 1.00 25.49 ? 9 SER C C 1 ATOM 2994 O O . SER C 3 11 ? 2.038 48.501 -36.868 1.00 25.19 ? 9 SER C O 1 ATOM 2995 C CB . SER C 3 11 ? 2.990 50.810 -34.753 1.00 25.20 ? 9 SER C CB 1 ATOM 2996 O OG . SER C 3 11 ? 2.736 51.354 -36.030 1.00 25.86 ? 9 SER C OG 1 ATOM 2997 N N . LEU C 3 12 ? 0.735 48.654 -35.044 1.00 24.36 ? 10 LEU C N 1 ATOM 2998 C CA . LEU C 3 12 ? -0.437 48.178 -35.747 1.00 23.73 ? 10 LEU C CA 1 ATOM 2999 C C . LEU C 3 12 ? -1.728 48.701 -35.122 1.00 24.48 ? 10 LEU C C 1 ATOM 3000 O O . LEU C 3 12 ? -1.786 48.977 -33.917 1.00 25.18 ? 10 LEU C O 1 ATOM 3001 C CB . LEU C 3 12 ? -0.440 46.651 -35.847 1.00 22.84 ? 10 LEU C CB 1 ATOM 3002 C CG . LEU C 3 12 ? -0.921 45.797 -34.678 1.00 21.96 ? 10 LEU C CG 1 ATOM 3003 C CD1 . LEU C 3 12 ? -1.572 44.553 -35.218 1.00 21.30 ? 10 LEU C CD1 1 ATOM 3004 C CD2 . LEU C 3 12 ? 0.215 45.443 -33.742 1.00 21.67 ? 10 LEU C CD2 1 ATOM 3005 N N . VAL C 3 13 ? -2.754 48.836 -35.965 1.00 24.35 ? 11 VAL C N 1 ATOM 3006 C CA . VAL C 3 13 ? -4.035 49.435 -35.596 1.00 24.01 ? 11 VAL C CA 1 ATOM 3007 C C . VAL C 3 13 ? -5.118 48.402 -35.859 1.00 23.91 ? 11 VAL C C 1 ATOM 3008 O O . VAL C 3 13 ? -5.140 47.797 -36.927 1.00 24.99 ? 11 VAL C O 1 ATOM 3009 C CB . VAL C 3 13 ? -4.308 50.702 -36.431 1.00 23.71 ? 11 VAL C CB 1 ATOM 3010 C CG1 . VAL C 3 13 ? -5.692 51.280 -36.110 1.00 24.17 ? 11 VAL C CG1 1 ATOM 3011 C CG2 . VAL C 3 13 ? -3.212 51.741 -36.209 1.00 22.41 ? 11 VAL C CG2 1 ATOM 3012 N N . VAL C 3 14 ? -6.016 48.215 -34.897 1.00 23.33 ? 12 VAL C N 1 ATOM 3013 C CA . VAL C 3 14 ? -6.913 47.061 -34.880 1.00 24.19 ? 12 VAL C CA 1 ATOM 3014 C C . VAL C 3 14 ? -8.273 47.415 -34.290 1.00 24.84 ? 12 VAL C C 1 ATOM 3015 O O . VAL C 3 14 ? -8.369 48.191 -33.337 1.00 24.83 ? 12 VAL C O 1 ATOM 3016 C CB . VAL C 3 14 ? -6.266 45.882 -34.065 1.00 23.99 ? 12 VAL C CB 1 ATOM 3017 C CG1 . VAL C 3 14 ? -7.304 45.078 -33.286 1.00 24.36 ? 12 VAL C CG1 1 ATOM 3018 C CG2 . VAL C 3 14 ? -5.446 44.976 -34.961 1.00 22.99 ? 12 VAL C CG2 1 ATOM 3019 N N . ARG C 3 15 ? -9.329 46.839 -34.846 1.00 26.34 ? 13 ARG C N 1 ATOM 3020 C CA . ARG C 3 15 ? -10.664 47.102 -34.327 1.00 28.38 ? 13 ARG C CA 1 ATOM 3021 C C . ARG C 3 15 ? -11.002 46.178 -33.148 1.00 28.78 ? 13 ARG C C 1 ATOM 3022 O O . ARG C 3 15 ? -10.712 44.974 -33.181 1.00 27.60 ? 13 ARG C O 1 ATOM 3023 C CB . ARG C 3 15 ? -11.705 47.044 -35.446 1.00 30.09 ? 13 ARG C CB 1 ATOM 3024 C CG . ARG C 3 15 ? -11.440 48.088 -36.531 1.00 35.09 ? 13 ARG C CG 1 ATOM 3025 C CD . ARG C 3 15 ? -12.656 48.384 -37.413 1.00 41.04 ? 13 ARG C CD 1 ATOM 3026 N NE . ARG C 3 15 ? -13.099 47.207 -38.169 1.00 47.69 ? 13 ARG C NE 1 ATOM 3027 C CZ . ARG C 3 15 ? -12.626 46.844 -39.363 1.00 50.15 ? 13 ARG C CZ 1 ATOM 3028 N NH1 . ARG C 3 15 ? -11.673 47.560 -39.962 1.00 52.75 ? 13 ARG C NH1 1 ATOM 3029 N NH2 . ARG C 3 15 ? -13.103 45.754 -39.957 1.00 48.81 ? 13 ARG C NH2 1 ATOM 3030 N N . GLN C 3 16 ? -11.583 46.755 -32.094 1.00 28.72 ? 14 GLN C N 1 ATOM 3031 C CA . GLN C 3 16 ? -12.034 45.985 -30.943 1.00 29.50 ? 14 GLN C CA 1 ATOM 3032 C C . GLN C 3 16 ? -12.749 44.697 -31.364 1.00 29.63 ? 14 GLN C C 1 ATOM 3033 O O . GLN C 3 16 ? -13.636 44.723 -32.210 1.00 29.76 ? 14 GLN C O 1 ATOM 3034 C CB . GLN C 3 16 ? -12.961 46.826 -30.088 1.00 31.64 ? 14 GLN C CB 1 ATOM 3035 C CG . GLN C 3 16 ? -14.049 46.009 -29.396 1.00 34.77 ? 14 GLN C CG 1 ATOM 3036 C CD . GLN C 3 16 ? -14.734 46.769 -28.287 1.00 37.24 ? 14 GLN C CD 1 ATOM 3037 O OE1 . GLN C 3 16 ? -14.620 48.004 -28.180 1.00 36.80 ? 14 GLN C OE1 1 ATOM 3038 N NE2 . GLN C 3 16 ? -15.458 46.034 -27.447 1.00 37.95 ? 14 GLN C NE2 1 ATOM 3039 N N . GLY C 3 17 ? -12.353 43.576 -30.772 1.00 29.04 ? 15 GLY C N 1 ATOM 3040 C CA . GLY C 3 17 ? -12.940 42.293 -31.104 1.00 28.35 ? 15 GLY C CA 1 ATOM 3041 C C . GLY C 3 17 ? -12.061 41.476 -32.025 1.00 29.33 ? 15 GLY C C 1 ATOM 3042 O O . GLY C 3 17 ? -12.128 40.254 -31.996 1.00 29.77 ? 15 GLY C O 1 ATOM 3043 N N . GLU C 3 18 ? -11.246 42.137 -32.849 1.00 29.71 ? 16 GLU C N 1 ATOM 3044 C CA . GLU C 3 18 ? -10.340 41.427 -33.765 1.00 31.13 ? 16 GLU C CA 1 ATOM 3045 C C . GLU C 3 18 ? -9.177 40.793 -32.979 1.00 30.53 ? 16 GLU C C 1 ATOM 3046 O O . GLU C 3 18 ? -8.827 41.263 -31.887 1.00 30.84 ? 16 GLU C O 1 ATOM 3047 C CB . GLU C 3 18 ? -9.813 42.361 -34.886 1.00 32.87 ? 16 GLU C CB 1 ATOM 3048 C CG . GLU C 3 18 ? -10.879 42.880 -35.891 1.00 35.21 ? 16 GLU C CG 1 ATOM 3049 C CD . GLU C 3 18 ? -10.391 44.020 -36.855 1.00 40.92 ? 16 GLU C CD 1 ATOM 3050 O OE1 . GLU C 3 18 ? -9.193 44.439 -36.825 1.00 38.44 ? 16 GLU C OE1 1 ATOM 3051 O OE2 . GLU C 3 18 ? -11.241 44.507 -37.658 1.00 42.90 ? 16 GLU C OE2 1 ATOM 3052 N N . ASN C 3 19 ? -8.597 39.723 -33.522 1.00 29.74 ? 17 ASN C N 1 ATOM 3053 C CA . ASN C 3 19 ? -7.393 39.108 -32.954 1.00 29.77 ? 17 ASN C CA 1 ATOM 3054 C C . ASN C 3 19 ? -6.145 39.643 -33.614 1.00 30.58 ? 17 ASN C C 1 ATOM 3055 O O . ASN C 3 19 ? -6.175 40.014 -34.794 1.00 32.15 ? 17 ASN C O 1 ATOM 3056 C CB . ASN C 3 19 ? -7.394 37.603 -33.167 1.00 30.22 ? 17 ASN C CB 1 ATOM 3057 C CG . ASN C 3 19 ? -8.626 36.943 -32.637 1.00 31.72 ? 17 ASN C CG 1 ATOM 3058 O OD1 . ASN C 3 19 ? -9.176 37.336 -31.595 1.00 32.29 ? 17 ASN C OD1 1 ATOM 3059 N ND2 . ASN C 3 19 ? -9.081 35.924 -33.350 1.00 31.15 ? 17 ASN C ND2 1 ATOM 3060 N N . CYS C 3 20 ? -5.038 39.664 -32.879 1.00 29.85 ? 18 CYS C N 1 ATOM 3061 C CA . CYS C 3 20 ? -3.759 40.031 -33.485 1.00 29.23 ? 18 CYS C CA 1 ATOM 3062 C C . CYS C 3 20 ? -2.592 39.185 -32.970 1.00 28.83 ? 18 CYS C C 1 ATOM 3063 O O . CYS C 3 20 ? -2.701 38.500 -31.938 1.00 28.23 ? 18 CYS C O 1 ATOM 3064 C CB . CYS C 3 20 ? -3.477 41.516 -33.304 1.00 29.08 ? 18 CYS C CB 1 ATOM 3065 S SG . CYS C 3 20 ? -3.127 41.932 -31.623 1.00 29.69 ? 18 CYS C SG 1 ATOM 3066 N N . VAL C 3 21 ? -1.483 39.249 -33.706 1.00 27.73 ? 19 VAL C N 1 ATOM 3067 C CA . VAL C 3 21 ? -0.321 38.397 -33.475 1.00 27.34 ? 19 VAL C CA 1 ATOM 3068 C C . VAL C 3 21 ? 0.944 39.244 -33.540 1.00 26.64 ? 19 VAL C C 1 ATOM 3069 O O . VAL C 3 21 ? 1.111 40.031 -34.448 1.00 24.94 ? 19 VAL C O 1 ATOM 3070 C CB . VAL C 3 21 ? -0.245 37.236 -34.521 1.00 27.38 ? 19 VAL C CB 1 ATOM 3071 C CG1 . VAL C 3 21 ? 1.090 36.509 -34.442 1.00 28.12 ? 19 VAL C CG1 1 ATOM 3072 C CG2 . VAL C 3 21 ? -1.382 36.244 -34.315 1.00 27.37 ? 19 VAL C CG2 1 ATOM 3073 N N . LEU C 3 22 ? 1.837 39.073 -32.577 1.00 27.75 ? 20 LEU C N 1 ATOM 3074 C CA . LEU C 3 22 ? 3.050 39.861 -32.543 1.00 28.58 ? 20 LEU C CA 1 ATOM 3075 C C . LEU C 3 22 ? 4.262 38.940 -32.618 1.00 30.77 ? 20 LEU C C 1 ATOM 3076 O O . LEU C 3 22 ? 4.341 37.959 -31.877 1.00 32.02 ? 20 LEU C O 1 ATOM 3077 C CB . LEU C 3 22 ? 3.071 40.677 -31.259 1.00 28.49 ? 20 LEU C CB 1 ATOM 3078 C CG . LEU C 3 22 ? 2.290 41.995 -31.175 1.00 29.04 ? 20 LEU C CG 1 ATOM 3079 C CD1 . LEU C 3 22 ? 0.846 41.932 -31.667 1.00 29.72 ? 20 LEU C CD1 1 ATOM 3080 C CD2 . LEU C 3 22 ? 2.321 42.508 -29.746 1.00 28.44 ? 20 LEU C CD2 1 ATOM 3081 N N . GLN C 3 23 ? 5.197 39.244 -33.516 1.00 31.54 ? 21 GLN C N 1 ATOM 3082 C CA . GLN C 3 23 ? 6.413 38.443 -33.662 1.00 32.36 ? 21 GLN C CA 1 ATOM 3083 C C . GLN C 3 23 ? 7.581 38.989 -32.831 1.00 32.79 ? 21 GLN C C 1 ATOM 3084 O O . GLN C 3 23 ? 7.723 40.203 -32.628 1.00 32.41 ? 21 GLN C O 1 ATOM 3085 C CB . GLN C 3 23 ? 6.868 38.374 -35.129 1.00 35.64 ? 21 GLN C CB 1 ATOM 3086 C CG . GLN C 3 23 ? 5.785 38.299 -36.186 1.00 38.61 ? 21 GLN C CG 1 ATOM 3087 C CD . GLN C 3 23 ? 4.907 37.063 -36.060 1.00 43.04 ? 21 GLN C CD 1 ATOM 3088 O OE1 . GLN C 3 23 ? 5.343 36.013 -35.564 1.00 43.78 ? 21 GLN C OE1 1 ATOM 3089 N NE2 . GLN C 3 23 ? 3.656 37.179 -36.521 1.00 43.44 ? 21 GLN C NE2 1 ATOM 3090 N N . CYS C 3 24 ? 8.422 38.070 -32.370 1.00 33.12 ? 22 CYS C N 1 ATOM 3091 C CA . CYS C 3 24 ? 9.726 38.391 -31.803 1.00 32.35 ? 22 CYS C CA 1 ATOM 3092 C C . CYS C 3 24 ? 10.756 37.437 -32.378 1.00 30.76 ? 22 CYS C C 1 ATOM 3093 O O . CYS C 3 24 ? 10.570 36.216 -32.369 1.00 31.40 ? 22 CYS C O 1 ATOM 3094 C CB . CYS C 3 24 ? 9.704 38.243 -30.291 1.00 34.08 ? 22 CYS C CB 1 ATOM 3095 S SG . CYS C 3 24 ? 11.210 38.826 -29.444 1.00 37.19 ? 22 CYS C SG 1 ATOM 3096 N N . ASN C 3 25 ? 11.834 37.993 -32.899 1.00 28.49 ? 23 ASN C N 1 ATOM 3097 C CA . ASN C 3 25 ? 12.931 37.175 -33.385 1.00 27.15 ? 23 ASN C CA 1 ATOM 3098 C C . ASN C 3 25 ? 14.218 37.632 -32.752 1.00 25.16 ? 23 ASN C C 1 ATOM 3099 O O . ASN C 3 25 ? 14.454 38.829 -32.624 1.00 25.94 ? 23 ASN C O 1 ATOM 3100 C CB . ASN C 3 25 ? 13.009 37.223 -34.905 1.00 27.75 ? 23 ASN C CB 1 ATOM 3101 C CG . ASN C 3 25 ? 11.944 36.357 -35.559 1.00 29.77 ? 23 ASN C CG 1 ATOM 3102 O OD1 . ASN C 3 25 ? 12.151 35.155 -35.778 1.00 30.23 ? 23 ASN C OD1 1 ATOM 3103 N ND2 . ASN C 3 25 ? 10.787 36.958 -35.863 1.00 29.52 ? 23 ASN C ND2 1 ATOM 3104 N N . TYR C 3 26 ? 15.037 36.686 -32.321 1.00 22.94 ? 24 TYR C N 1 ATOM 3105 C CA . TYR C 3 26 ? 16.262 37.051 -31.627 1.00 22.97 ? 24 TYR C CA 1 ATOM 3106 C C . TYR C 3 26 ? 17.524 36.291 -32.088 1.00 22.94 ? 24 TYR C C 1 ATOM 3107 O O . TYR C 3 26 ? 17.445 35.248 -32.744 1.00 23.14 ? 24 TYR C O 1 ATOM 3108 C CB . TYR C 3 26 ? 16.052 36.935 -30.111 1.00 21.27 ? 24 TYR C CB 1 ATOM 3109 C CG . TYR C 3 26 ? 15.693 35.549 -29.650 1.00 20.53 ? 24 TYR C CG 1 ATOM 3110 C CD1 . TYR C 3 26 ? 16.689 34.652 -29.270 1.00 20.17 ? 24 TYR C CD1 1 ATOM 3111 C CD2 . TYR C 3 26 ? 14.357 35.130 -29.590 1.00 20.29 ? 24 TYR C CD2 1 ATOM 3112 C CE1 . TYR C 3 26 ? 16.377 33.370 -28.842 1.00 20.50 ? 24 TYR C CE1 1 ATOM 3113 C CE2 . TYR C 3 26 ? 14.026 33.841 -29.163 1.00 20.13 ? 24 TYR C CE2 1 ATOM 3114 C CZ . TYR C 3 26 ? 15.050 32.966 -28.789 1.00 20.72 ? 24 TYR C CZ 1 ATOM 3115 O OH . TYR C 3 26 ? 14.768 31.684 -28.366 1.00 20.80 ? 24 TYR C OH 1 ATOM 3116 N N . SER C 3 27 ? 18.685 36.833 -31.739 1.00 22.77 ? 25 SER C N 1 ATOM 3117 C CA . SER C 3 27 ? 19.954 36.140 -31.948 1.00 22.56 ? 25 SER C CA 1 ATOM 3118 C C . SER C 3 27 ? 20.703 35.906 -30.621 1.00 23.79 ? 25 SER C C 1 ATOM 3119 O O . SER C 3 27 ? 21.821 35.387 -30.629 1.00 24.55 ? 25 SER C O 1 ATOM 3120 C CB . SER C 3 27 ? 20.833 36.911 -32.933 1.00 21.12 ? 25 SER C CB 1 ATOM 3121 O OG . SER C 3 27 ? 20.981 38.259 -32.524 1.00 20.49 ? 25 SER C OG 1 ATOM 3122 N N . VAL C 3 28 ? 20.085 36.271 -29.490 1.00 23.55 ? 26 VAL C N 1 ATOM 3123 C CA . VAL C 3 28 ? 20.700 36.100 -28.162 1.00 22.86 ? 26 VAL C CA 1 ATOM 3124 C C . VAL C 3 28 ? 21.215 34.674 -27.940 1.00 23.40 ? 26 VAL C C 1 ATOM 3125 O O . VAL C 3 28 ? 20.501 33.719 -28.238 1.00 23.55 ? 26 VAL C O 1 ATOM 3126 C CB . VAL C 3 28 ? 19.713 36.453 -27.018 1.00 21.39 ? 26 VAL C CB 1 ATOM 3127 C CG1 . VAL C 3 28 ? 20.380 36.273 -25.676 1.00 20.97 ? 26 VAL C CG1 1 ATOM 3128 C CG2 . VAL C 3 28 ? 19.214 37.866 -27.148 1.00 20.77 ? 26 VAL C CG2 1 ATOM 3129 N N . THR C 3 29 ? 22.444 34.535 -27.423 1.00 24.29 ? 27 THR C N 1 ATOM 3130 C CA . THR C 3 29 ? 22.995 33.208 -27.045 1.00 24.98 ? 27 THR C CA 1 ATOM 3131 C C . THR C 3 29 ? 23.672 33.168 -25.677 1.00 24.84 ? 27 THR C C 1 ATOM 3132 O O . THR C 3 29 ? 24.522 34.006 -25.390 1.00 25.50 ? 27 THR C O 1 ATOM 3133 C CB . THR C 3 29 ? 24.015 32.671 -28.071 1.00 24.38 ? 27 THR C CB 1 ATOM 3134 O OG1 . THR C 3 29 ? 23.534 32.930 -29.382 1.00 25.30 ? 27 THR C OG1 1 ATOM 3135 C CG2 . THR C 3 29 ? 24.220 31.160 -27.909 1.00 23.65 ? 27 THR C CG2 1 ATOM 3136 N N . PRO C 3 30 ? 23.303 32.187 -24.832 1.00 25.09 ? 28 PRO C N 1 ATOM 3137 C CA . PRO C 3 30 ? 22.146 31.318 -25.019 1.00 24.95 ? 28 PRO C CA 1 ATOM 3138 C C . PRO C 3 30 ? 20.836 32.025 -24.692 1.00 25.46 ? 28 PRO C C 1 ATOM 3139 O O . PRO C 3 30 ? 20.828 33.184 -24.266 1.00 24.80 ? 28 PRO C O 1 ATOM 3140 C CB . PRO C 3 30 ? 22.395 30.170 -24.034 1.00 24.65 ? 28 PRO C CB 1 ATOM 3141 C CG . PRO C 3 30 ? 23.323 30.732 -23.025 1.00 24.58 ? 28 PRO C CG 1 ATOM 3142 C CD . PRO C 3 30 ? 24.198 31.678 -23.776 1.00 24.88 ? 28 PRO C CD 1 ATOM 3143 N N . ASP C 3 31 ? 19.743 31.309 -24.928 1.00 26.02 ? 29 ASP C N 1 ATOM 3144 C CA . ASP C 3 31 ? 18.402 31.783 -24.672 1.00 25.58 ? 29 ASP C CA 1 ATOM 3145 C C . ASP C 3 31 ? 17.754 30.876 -23.642 1.00 25.16 ? 29 ASP C C 1 ATOM 3146 O O . ASP C 3 31 ? 17.119 29.863 -23.972 1.00 26.56 ? 29 ASP C O 1 ATOM 3147 C CB . ASP C 3 31 ? 17.583 31.807 -25.965 1.00 27.16 ? 29 ASP C CB 1 ATOM 3148 C CG . ASP C 3 31 ? 17.781 30.560 -26.825 1.00 28.53 ? 29 ASP C CG 1 ATOM 3149 O OD1 . ASP C 3 31 ? 18.756 29.808 -26.608 1.00 28.93 ? 29 ASP C OD1 1 ATOM 3150 O OD2 . ASP C 3 31 ? 16.954 30.338 -27.736 1.00 30.28 ? 29 ASP C OD2 1 ATOM 3151 N N . ASN C 3 32 ? 17.947 31.227 -22.381 1.00 23.75 ? 30 ASN C N 1 ATOM 3152 C CA . ASN C 3 32 ? 17.317 30.502 -21.308 1.00 23.05 ? 30 ASN C CA 1 ATOM 3153 C C . ASN C 3 32 ? 15.806 30.677 -21.332 1.00 22.84 ? 30 ASN C C 1 ATOM 3154 O O . ASN C 3 32 ? 15.071 29.697 -21.270 1.00 23.33 ? 30 ASN C O 1 ATOM 3155 C CB . ASN C 3 32 ? 17.859 30.938 -19.956 1.00 22.22 ? 30 ASN C CB 1 ATOM 3156 C CG . ASN C 3 32 ? 17.168 30.231 -18.824 1.00 21.84 ? 30 ASN C CG 1 ATOM 3157 O OD1 . ASN C 3 32 ? 16.277 30.789 -18.189 1.00 21.45 ? 30 ASN C OD1 1 ATOM 3158 N ND2 . ASN C 3 32 ? 17.537 28.972 -18.594 1.00 21.28 ? 30 ASN C ND2 1 ATOM 3159 N N . HIS C 3 33 ? 15.347 31.920 -21.412 1.00 22.20 ? 31 HIS C N 1 ATOM 3160 C CA . HIS C 3 33 ? 13.921 32.184 -21.421 1.00 22.64 ? 31 HIS C CA 1 ATOM 3161 C C . HIS C 3 33 ? 13.543 33.438 -22.152 1.00 22.62 ? 31 HIS C C 1 ATOM 3162 O O . HIS C 3 33 ? 14.354 34.356 -22.314 1.00 22.19 ? 31 HIS C O 1 ATOM 3163 C CB . HIS C 3 33 ? 13.398 32.262 -20.001 1.00 23.47 ? 31 HIS C CB 1 ATOM 3164 C CG . HIS C 3 33 ? 13.952 33.424 -19.216 1.00 24.07 ? 31 HIS C CG 1 ATOM 3165 N ND1 . HIS C 3 33 ? 15.047 33.319 -18.453 1.00 24.03 ? 31 HIS C ND1 1 ATOM 3166 C CD2 . HIS C 3 33 ? 13.524 34.744 -19.114 1.00 24.61 ? 31 HIS C CD2 1 ATOM 3167 C CE1 . HIS C 3 33 ? 15.315 34.509 -17.886 1.00 24.75 ? 31 HIS C CE1 1 ATOM 3168 N NE2 . HIS C 3 33 ? 14.378 35.380 -18.288 1.00 25.08 ? 31 HIS C NE2 1 ATOM 3169 N N . LEU C 3 34 ? 12.285 33.480 -22.581 1.00 22.37 ? 32 LEU C N 1 ATOM 3170 C CA . LEU C 3 34 ? 11.705 34.646 -23.222 1.00 22.31 ? 32 LEU C CA 1 ATOM 3171 C C . LEU C 3 34 ? 10.467 35.092 -22.447 1.00 22.74 ? 32 LEU C C 1 ATOM 3172 O O . LEU C 3 34 ? 9.641 34.261 -22.030 1.00 23.67 ? 32 LEU C O 1 ATOM 3173 C CB . LEU C 3 34 ? 11.356 34.320 -24.671 1.00 22.11 ? 32 LEU C CB 1 ATOM 3174 C CG . LEU C 3 34 ? 10.959 35.476 -25.592 1.00 22.65 ? 32 LEU C CG 1 ATOM 3175 C CD1 . LEU C 3 34 ? 11.288 35.128 -27.016 1.00 22.02 ? 32 LEU C CD1 1 ATOM 3176 C CD2 . LEU C 3 34 ? 9.481 35.835 -25.454 1.00 22.37 ? 32 LEU C CD2 1 ATOM 3177 N N . ARG C 3 35 ? 10.341 36.401 -22.250 1.00 22.36 ? 33 ARG C N 1 ATOM 3178 C CA . ARG C 3 35 ? 9.225 36.958 -21.500 1.00 21.93 ? 33 ARG C CA 1 ATOM 3179 C C . ARG C 3 35 ? 8.541 38.080 -22.259 1.00 21.12 ? 33 ARG C C 1 ATOM 3180 O O . ARG C 3 35 ? 9.198 38.896 -22.895 1.00 21.70 ? 33 ARG C O 1 ATOM 3181 C CB . ARG C 3 35 ? 9.742 37.487 -20.181 1.00 23.09 ? 33 ARG C CB 1 ATOM 3182 C CG . ARG C 3 35 ? 8.680 38.056 -19.277 1.00 25.27 ? 33 ARG C CG 1 ATOM 3183 C CD . ARG C 3 35 ? 9.322 38.827 -18.155 1.00 26.66 ? 33 ARG C CD 1 ATOM 3184 N NE . ARG C 3 35 ? 10.149 37.965 -17.310 1.00 28.00 ? 33 ARG C NE 1 ATOM 3185 C CZ . ARG C 3 35 ? 9.703 37.353 -16.222 1.00 29.19 ? 33 ARG C CZ 1 ATOM 3186 N NH1 . ARG C 3 35 ? 8.437 37.518 -15.866 1.00 29.82 ? 33 ARG C NH1 1 ATOM 3187 N NH2 . ARG C 3 35 ? 10.518 36.588 -15.492 1.00 29.34 ? 33 ARG C NH2 1 ATOM 3188 N N . TRP C 3 36 ? 7.222 38.133 -22.176 1.00 20.61 ? 34 TRP C N 1 ATOM 3189 C CA . TRP C 3 36 ? 6.472 39.226 -22.778 1.00 21.37 ? 34 TRP C CA 1 ATOM 3190 C C . TRP C 3 36 ? 5.937 40.235 -21.776 1.00 22.45 ? 34 TRP C C 1 ATOM 3191 O O . TRP C 3 36 ? 5.192 39.882 -20.848 1.00 23.51 ? 34 TRP C O 1 ATOM 3192 C CB . TRP C 3 36 ? 5.325 38.657 -23.592 1.00 20.89 ? 34 TRP C CB 1 ATOM 3193 C CG . TRP C 3 36 ? 5.721 38.128 -24.941 1.00 20.24 ? 34 TRP C CG 1 ATOM 3194 C CD1 . TRP C 3 36 ? 6.041 36.823 -25.283 1.00 19.68 ? 34 TRP C CD1 1 ATOM 3195 C CD2 . TRP C 3 36 ? 5.830 38.886 -26.193 1.00 20.06 ? 34 TRP C CD2 1 ATOM 3196 N NE1 . TRP C 3 36 ? 6.330 36.723 -26.623 1.00 19.34 ? 34 TRP C NE1 1 ATOM 3197 C CE2 . TRP C 3 36 ? 6.222 37.919 -27.226 1.00 19.51 ? 34 TRP C CE2 1 ATOM 3198 C CE3 . TRP C 3 36 ? 5.639 40.215 -26.553 1.00 19.46 ? 34 TRP C CE3 1 ATOM 3199 C CZ2 . TRP C 3 36 ? 6.415 38.292 -28.546 1.00 19.54 ? 34 TRP C CZ2 1 ATOM 3200 C CZ3 . TRP C 3 36 ? 5.843 40.575 -27.889 1.00 19.13 ? 34 TRP C CZ3 1 ATOM 3201 C CH2 . TRP C 3 36 ? 6.223 39.635 -28.858 1.00 19.07 ? 34 TRP C CH2 1 ATOM 3202 N N . PHE C 3 37 ? 6.289 41.505 -21.964 1.00 22.92 ? 35 PHE C N 1 ATOM 3203 C CA . PHE C 3 37 ? 5.785 42.588 -21.110 1.00 23.18 ? 35 PHE C CA 1 ATOM 3204 C C . PHE C 3 37 ? 4.730 43.437 -21.822 1.00 23.12 ? 35 PHE C C 1 ATOM 3205 O O . PHE C 3 37 ? 4.795 43.611 -23.044 1.00 23.04 ? 35 PHE C O 1 ATOM 3206 C CB . PHE C 3 37 ? 6.933 43.517 -20.721 1.00 23.23 ? 35 PHE C CB 1 ATOM 3207 C CG . PHE C 3 37 ? 7.749 43.051 -19.548 1.00 23.12 ? 35 PHE C CG 1 ATOM 3208 C CD1 . PHE C 3 37 ? 7.215 43.046 -18.265 1.00 23.12 ? 35 PHE C CD1 1 ATOM 3209 C CD2 . PHE C 3 37 ? 9.081 42.673 -19.719 1.00 23.37 ? 35 PHE C CD2 1 ATOM 3210 C CE1 . PHE C 3 37 ? 7.989 42.644 -17.166 1.00 23.07 ? 35 PHE C CE1 1 ATOM 3211 C CE2 . PHE C 3 37 ? 9.866 42.263 -18.624 1.00 23.23 ? 35 PHE C CE2 1 ATOM 3212 C CZ . PHE C 3 37 ? 9.322 42.250 -17.350 1.00 22.68 ? 35 PHE C CZ 1 ATOM 3213 N N . LYS C 3 38 ? 3.786 43.985 -21.052 1.00 23.38 ? 36 LYS C N 1 ATOM 3214 C CA . LYS C 3 38 ? 2.819 45.000 -21.538 1.00 23.64 ? 36 LYS C CA 1 ATOM 3215 C C . LYS C 3 38 ? 3.135 46.336 -20.886 1.00 23.56 ? 36 LYS C C 1 ATOM 3216 O O . LYS C 3 38 ? 3.380 46.377 -19.677 1.00 25.17 ? 36 LYS C O 1 ATOM 3217 C CB . LYS C 3 38 ? 1.393 44.596 -21.158 1.00 23.72 ? 36 LYS C CB 1 ATOM 3218 C CG . LYS C 3 38 ? 0.266 45.479 -21.693 1.00 23.24 ? 36 LYS C CG 1 ATOM 3219 C CD . LYS C 3 38 ? -1.078 44.882 -21.271 1.00 23.28 ? 36 LYS C CD 1 ATOM 3220 C CE . LYS C 3 38 ? -2.281 45.592 -21.900 1.00 24.55 ? 36 LYS C CE 1 ATOM 3221 N NZ . LYS C 3 38 ? -2.706 46.796 -21.140 1.00 25.33 ? 36 LYS C NZ 1 ATOM 3222 N N . GLN C 3 39 ? 3.137 47.418 -21.664 1.00 22.34 ? 37 GLN C N 1 ATOM 3223 C CA . GLN C 3 39 ? 3.395 48.761 -21.113 1.00 21.98 ? 37 GLN C CA 1 ATOM 3224 C C . GLN C 3 39 ? 2.401 49.820 -21.619 1.00 23.33 ? 37 GLN C C 1 ATOM 3225 O O . GLN C 3 39 ? 2.386 50.170 -22.802 1.00 23.80 ? 37 GLN C O 1 ATOM 3226 C CB . GLN C 3 39 ? 4.846 49.188 -21.361 1.00 19.55 ? 37 GLN C CB 1 ATOM 3227 C CG . GLN C 3 39 ? 5.222 50.526 -20.746 1.00 18.40 ? 37 GLN C CG 1 ATOM 3228 C CD . GLN C 3 39 ? 6.668 50.959 -21.027 1.00 17.90 ? 37 GLN C CD 1 ATOM 3229 O OE1 . GLN C 3 39 ? 7.236 50.654 -22.072 1.00 17.30 ? 37 GLN C OE1 1 ATOM 3230 N NE2 . GLN C 3 39 ? 7.259 51.691 -20.085 1.00 17.66 ? 37 GLN C NE2 1 ATOM 3231 N N . ASP C 3 40 ? 1.558 50.315 -20.722 1.00 25.91 ? 38 ASP C N 1 ATOM 3232 C CA . ASP C 3 40 ? 0.649 51.405 -21.058 1.00 29.00 ? 38 ASP C CA 1 ATOM 3233 C C . ASP C 3 40 ? 1.493 52.661 -21.127 1.00 30.41 ? 38 ASP C C 1 ATOM 3234 O O . ASP C 3 40 ? 2.470 52.796 -20.374 1.00 30.85 ? 38 ASP C O 1 ATOM 3235 C CB . ASP C 3 40 ? -0.426 51.599 -19.982 1.00 32.21 ? 38 ASP C CB 1 ATOM 3236 C CG . ASP C 3 40 ? -1.254 50.345 -19.708 1.00 35.08 ? 38 ASP C CG 1 ATOM 3237 O OD1 . ASP C 3 40 ? -1.288 49.393 -20.527 1.00 37.15 ? 38 ASP C OD1 1 ATOM 3238 O OD2 . ASP C 3 40 ? -1.890 50.320 -18.638 1.00 37.82 ? 38 ASP C OD2 1 ATOM 3239 N N . THR C 3 41 ? 1.138 53.584 -22.015 1.00 32.58 ? 39 THR C N 1 ATOM 3240 C CA . THR C 3 41 ? 1.907 54.828 -22.116 1.00 34.98 ? 39 THR C CA 1 ATOM 3241 C C . THR C 3 41 ? 1.851 55.522 -20.759 1.00 34.48 ? 39 THR C C 1 ATOM 3242 O O . THR C 3 41 ? 0.775 55.648 -20.154 1.00 33.19 ? 39 THR C O 1 ATOM 3243 C CB . THR C 3 41 ? 1.424 55.756 -23.257 1.00 35.88 ? 39 THR C CB 1 ATOM 3244 O OG1 . THR C 3 41 ? 0.006 55.905 -23.173 1.00 34.15 ? 39 THR C OG1 1 ATOM 3245 C CG2 . THR C 3 41 ? 1.824 55.184 -24.654 1.00 35.73 ? 39 THR C CG2 1 ATOM 3246 N N . GLY C 3 42 ? 3.028 55.911 -20.272 1.00 34.39 ? 40 GLY C N 1 ATOM 3247 C CA . GLY C 3 42 ? 3.188 56.371 -18.895 1.00 35.89 ? 40 GLY C CA 1 ATOM 3248 C C . GLY C 3 42 ? 2.880 55.265 -17.892 1.00 37.39 ? 40 GLY C C 1 ATOM 3249 O O . GLY C 3 42 ? 1.857 55.292 -17.198 1.00 38.37 ? 40 GLY C O 1 ATOM 3250 N N . LYS C 3 43 ? 3.745 54.264 -17.830 1.00 35.27 ? 41 LYS C N 1 ATOM 3251 C CA . LYS C 3 43 ? 3.552 53.205 -16.859 1.00 33.99 ? 41 LYS C CA 1 ATOM 3252 C C . LYS C 3 43 ? 4.656 52.151 -16.948 1.00 32.33 ? 41 LYS C C 1 ATOM 3253 O O . LYS C 3 43 ? 5.542 52.199 -17.808 1.00 29.59 ? 41 LYS C O 1 ATOM 3254 C CB . LYS C 3 43 ? 2.145 52.582 -16.980 1.00 34.38 ? 41 LYS C CB 1 ATOM 3255 N N . GLY C 3 44 ? 4.606 51.210 -16.023 1.00 30.88 ? 42 GLY C N 1 ATOM 3256 C CA . GLY C 3 44 ? 5.680 50.264 -15.892 1.00 31.01 ? 42 GLY C CA 1 ATOM 3257 C C . GLY C 3 44 ? 5.426 49.032 -16.712 1.00 30.12 ? 42 GLY C C 1 ATOM 3258 O O . GLY C 3 44 ? 4.467 48.958 -17.485 1.00 29.41 ? 42 GLY C O 1 ATOM 3259 N N . LEU C 3 45 ? 6.288 48.051 -16.502 1.00 28.45 ? 43 LEU C N 1 ATOM 3260 C CA . LEU C 3 45 ? 6.266 46.848 -17.270 1.00 27.51 ? 43 LEU C CA 1 ATOM 3261 C C . LEU C 3 45 ? 5.540 45.757 -16.490 1.00 27.54 ? 43 LEU C C 1 ATOM 3262 O O . LEU C 3 45 ? 6.001 45.322 -15.442 1.00 28.67 ? 43 LEU C O 1 ATOM 3263 C CB . LEU C 3 45 ? 7.704 46.454 -17.583 1.00 27.73 ? 43 LEU C CB 1 ATOM 3264 C CG . LEU C 3 45 ? 8.583 47.600 -18.094 1.00 27.65 ? 43 LEU C CG 1 ATOM 3265 C CD1 . LEU C 3 45 ? 10.042 47.399 -17.645 1.00 28.44 ? 43 LEU C CD1 1 ATOM 3266 C CD2 . LEU C 3 45 ? 8.480 47.729 -19.587 1.00 25.68 ? 43 LEU C CD2 1 ATOM 3267 N N . VAL C 3 46 ? 4.394 45.334 -17.009 1.00 26.86 ? 44 VAL C N 1 ATOM 3268 C CA . VAL C 3 46 ? 3.613 44.241 -16.437 1.00 26.01 ? 44 VAL C CA 1 ATOM 3269 C C . VAL C 3 46 ? 3.872 42.959 -17.239 1.00 26.29 ? 44 VAL C C 1 ATOM 3270 O O . VAL C 3 46 ? 3.690 42.944 -18.455 1.00 27.40 ? 44 VAL C O 1 ATOM 3271 C CB . VAL C 3 46 ? 2.100 44.583 -16.467 1.00 25.65 ? 44 VAL C CB 1 ATOM 3272 C CG1 . VAL C 3 46 ? 1.267 43.486 -15.821 1.00 24.66 ? 44 VAL C CG1 1 ATOM 3273 C CG2 . VAL C 3 46 ? 1.853 45.928 -15.784 1.00 25.48 ? 44 VAL C CG2 1 ATOM 3274 N N . SER C 3 47 ? 4.299 41.894 -16.560 1.00 25.31 ? 45 SER C N 1 ATOM 3275 C CA . SER C 3 47 ? 4.583 40.619 -17.211 1.00 23.91 ? 45 SER C CA 1 ATOM 3276 C C . SER C 3 47 ? 3.313 39.859 -17.637 1.00 24.02 ? 45 SER C C 1 ATOM 3277 O O . SER C 3 47 ? 2.381 39.676 -16.844 1.00 24.28 ? 45 SER C O 1 ATOM 3278 C CB . SER C 3 47 ? 5.444 39.745 -16.294 1.00 23.21 ? 45 SER C CB 1 ATOM 3279 O OG . SER C 3 47 ? 5.585 38.426 -16.810 1.00 23.41 ? 45 SER C OG 1 ATOM 3280 N N . LEU C 3 48 ? 3.277 39.398 -18.884 1.00 23.10 ? 46 LEU C N 1 ATOM 3281 C CA . LEU C 3 48 ? 2.125 38.627 -19.339 1.00 23.22 ? 46 LEU C CA 1 ATOM 3282 C C . LEU C 3 48 ? 2.397 37.139 -19.242 1.00 24.26 ? 46 LEU C C 1 ATOM 3283 O O . LEU C 3 48 ? 1.527 36.361 -18.850 1.00 24.95 ? 46 LEU C O 1 ATOM 3284 C CB . LEU C 3 48 ? 1.708 39.025 -20.757 1.00 21.93 ? 46 LEU C CB 1 ATOM 3285 C CG . LEU C 3 48 ? 1.407 40.516 -20.886 1.00 21.59 ? 46 LEU C CG 1 ATOM 3286 C CD1 . LEU C 3 48 ? 1.311 40.954 -22.332 1.00 21.60 ? 46 LEU C CD1 1 ATOM 3287 C CD2 . LEU C 3 48 ? 0.158 40.883 -20.103 1.00 21.17 ? 46 LEU C CD2 1 ATOM 3288 N N . THR C 3 49 ? 3.615 36.744 -19.580 1.00 24.91 ? 47 THR C N 1 ATOM 3289 C CA . THR C 3 49 ? 3.965 35.336 -19.613 1.00 25.07 ? 47 THR C CA 1 ATOM 3290 C C . THR C 3 49 ? 5.472 35.164 -19.787 1.00 24.80 ? 47 THR C C 1 ATOM 3291 O O . THR C 3 49 ? 6.170 36.086 -20.217 1.00 25.64 ? 47 THR C O 1 ATOM 3292 C CB . THR C 3 49 ? 3.185 34.587 -20.745 1.00 25.51 ? 47 THR C CB 1 ATOM 3293 O OG1 . THR C 3 49 ? 3.298 33.172 -20.553 1.00 26.30 ? 47 THR C OG1 1 ATOM 3294 C CG2 . THR C 3 49 ? 3.693 34.963 -22.138 1.00 24.59 ? 47 THR C CG2 1 ATOM 3295 N N . VAL C 3 50 ? 5.966 33.987 -19.434 1.00 23.80 ? 48 VAL C N 1 ATOM 3296 C CA . VAL C 3 50 ? 7.367 33.664 -19.626 1.00 23.48 ? 48 VAL C CA 1 ATOM 3297 C C . VAL C 3 50 ? 7.434 32.247 -20.162 1.00 23.66 ? 48 VAL C C 1 ATOM 3298 O O . VAL C 3 50 ? 6.823 31.345 -19.605 1.00 24.03 ? 48 VAL C O 1 ATOM 3299 C CB . VAL C 3 50 ? 8.200 33.848 -18.323 1.00 22.30 ? 48 VAL C CB 1 ATOM 3300 C CG1 . VAL C 3 50 ? 7.519 33.222 -17.151 1.00 21.55 ? 48 VAL C CG1 1 ATOM 3301 C CG2 . VAL C 3 50 ? 9.598 33.283 -18.494 1.00 22.49 ? 48 VAL C CG2 1 ATOM 3302 N N . LEU C 3 51 ? 8.151 32.069 -21.264 1.00 23.89 ? 49 LEU C N 1 ATOM 3303 C CA . LEU C 3 51 ? 8.271 30.772 -21.917 1.00 24.43 ? 49 LEU C CA 1 ATOM 3304 C C . LEU C 3 51 ? 9.681 30.255 -21.703 1.00 24.90 ? 49 LEU C C 1 ATOM 3305 O O . LEU C 3 51 ? 10.649 31.009 -21.872 1.00 25.15 ? 49 LEU C O 1 ATOM 3306 C CB . LEU C 3 51 ? 8.015 30.926 -23.414 1.00 24.83 ? 49 LEU C CB 1 ATOM 3307 C CG . LEU C 3 51 ? 6.708 31.589 -23.834 1.00 24.21 ? 49 LEU C CG 1 ATOM 3308 C CD1 . LEU C 3 51 ? 7.035 32.723 -24.766 1.00 24.97 ? 49 LEU C CD1 1 ATOM 3309 C CD2 . LEU C 3 51 ? 5.751 30.601 -24.472 1.00 23.68 ? 49 LEU C CD2 1 ATOM 3310 N N . VAL C 3 52 ? 9.814 28.978 -21.342 1.00 25.10 ? 50 VAL C N 1 ATOM 3311 C CA . VAL C 3 52 ? 11.134 28.452 -20.934 1.00 24.92 ? 50 VAL C CA 1 ATOM 3312 C C . VAL C 3 52 ? 11.634 27.194 -21.649 1.00 26.19 ? 50 VAL C C 1 ATOM 3313 O O . VAL C 3 52 ? 12.824 26.950 -21.648 1.00 26.92 ? 50 VAL C O 1 ATOM 3314 C CB . VAL C 3 52 ? 11.246 28.259 -19.401 1.00 23.32 ? 50 VAL C CB 1 ATOM 3315 C CG1 . VAL C 3 52 ? 10.736 29.491 -18.664 1.00 22.03 ? 50 VAL C CG1 1 ATOM 3316 C CG2 . VAL C 3 52 ? 10.499 27.016 -18.955 1.00 23.15 ? 50 VAL C CG2 1 ATOM 3317 N N . ASP C 3 53 ? 10.743 26.412 -22.256 1.00 28.51 ? 51 ASP C N 1 ATOM 3318 C CA . ASP C 3 53 ? 11.134 25.159 -22.905 1.00 30.15 ? 51 ASP C CA 1 ATOM 3319 C C . ASP C 3 53 ? 11.528 25.345 -24.362 1.00 31.65 ? 51 ASP C C 1 ATOM 3320 O O . ASP C 3 53 ? 11.081 26.292 -25.013 1.00 31.96 ? 51 ASP C O 1 ATOM 3321 C CB . ASP C 3 53 ? 10.015 24.118 -22.802 1.00 32.45 ? 51 ASP C CB 1 ATOM 3322 C CG . ASP C 3 53 ? 9.823 23.591 -21.381 1.00 35.22 ? 51 ASP C CG 1 ATOM 3323 O OD1 . ASP C 3 53 ? 10.792 23.570 -20.583 1.00 38.11 ? 51 ASP C OD1 1 ATOM 3324 O OD2 . ASP C 3 53 ? 8.688 23.189 -21.057 1.00 36.58 ? 51 ASP C OD2 1 ATOM 3325 N N . GLN C 3 54 ? 12.358 24.422 -24.865 1.00 33.09 ? 52 GLN C N 1 ATOM 3326 C CA . GLN C 3 54 ? 12.863 24.441 -26.251 1.00 33.25 ? 52 GLN C CA 1 ATOM 3327 C C . GLN C 3 54 ? 11.766 24.739 -27.287 1.00 32.83 ? 52 GLN C C 1 ATOM 3328 O O . GLN C 3 54 ? 11.965 25.522 -28.225 1.00 32.24 ? 52 GLN C O 1 ATOM 3329 C CB . GLN C 3 54 ? 13.587 23.126 -26.578 1.00 33.46 ? 52 GLN C CB 1 ATOM 3330 C CG . GLN C 3 54 ? 14.642 23.229 -27.700 1.00 36.58 ? 52 GLN C CG 1 ATOM 3331 C CD . GLN C 3 54 ? 15.839 24.167 -27.379 1.00 39.98 ? 52 GLN C CD 1 ATOM 3332 O OE1 . GLN C 3 54 ? 16.120 24.500 -26.215 1.00 40.76 ? 52 GLN C OE1 1 ATOM 3333 N NE2 . GLN C 3 54 ? 16.546 24.585 -28.426 1.00 40.55 ? 52 GLN C NE2 1 ATOM 3334 N N . LYS C 3 55 ? 10.621 24.089 -27.105 1.00 32.56 ? 53 LYS C N 1 ATOM 3335 C CA . LYS C 3 55 ? 9.393 24.431 -27.805 1.00 32.74 ? 53 LYS C CA 1 ATOM 3336 C C . LYS C 3 55 ? 8.337 24.605 -26.734 1.00 32.51 ? 53 LYS C C 1 ATOM 3337 O O . LYS C 3 55 ? 8.006 23.652 -26.025 1.00 34.61 ? 53 LYS C O 1 ATOM 3338 C CB . LYS C 3 55 ? 9.003 23.359 -28.826 1.00 31.52 ? 53 LYS C CB 1 ATOM 3339 C CG . LYS C 3 55 ? 9.932 23.352 -30.019 1.00 33.37 ? 53 LYS C CG 1 ATOM 3340 C CD . LYS C 3 55 ? 9.497 22.380 -31.100 1.00 35.83 ? 53 LYS C CD 1 ATOM 3341 C CE . LYS C 3 55 ? 10.685 21.980 -31.998 1.00 37.31 ? 53 LYS C CE 1 ATOM 3342 N NZ . LYS C 3 55 ? 11.410 23.158 -32.593 1.00 37.71 ? 53 LYS C NZ 1 ATOM 3343 N N . ASP C 3 56 ? 7.839 25.829 -26.592 1.00 31.00 ? 54 ASP C N 1 ATOM 3344 C CA . ASP C 3 56 ? 6.938 26.145 -25.498 1.00 29.81 ? 54 ASP C CA 1 ATOM 3345 C C . ASP C 3 56 ? 5.700 26.909 -25.939 1.00 29.79 ? 54 ASP C C 1 ATOM 3346 O O . ASP C 3 56 ? 5.733 27.685 -26.905 1.00 28.35 ? 54 ASP C O 1 ATOM 3347 C CB . ASP C 3 56 ? 7.674 26.941 -24.427 1.00 30.96 ? 54 ASP C CB 1 ATOM 3348 C CG . ASP C 3 56 ? 7.179 26.631 -23.041 1.00 32.42 ? 54 ASP C CG 1 ATOM 3349 O OD1 . ASP C 3 56 ? 6.050 26.106 -22.957 1.00 33.71 ? 54 ASP C OD1 1 ATOM 3350 O OD2 . ASP C 3 56 ? 7.911 26.892 -22.045 1.00 31.61 ? 54 ASP C OD2 1 ATOM 3351 N N . LYS C 3 57 ? 4.612 26.672 -25.208 1.00 29.06 ? 55 LYS C N 1 ATOM 3352 C CA . LYS C 3 57 ? 3.343 27.352 -25.397 1.00 28.47 ? 55 LYS C CA 1 ATOM 3353 C C . LYS C 3 57 ? 2.850 27.747 -24.024 1.00 28.70 ? 55 LYS C C 1 ATOM 3354 O O . LYS C 3 57 ? 3.026 26.989 -23.080 1.00 30.05 ? 55 LYS C O 1 ATOM 3355 C CB . LYS C 3 57 ? 2.326 26.407 -26.026 1.00 28.68 ? 55 LYS C CB 1 ATOM 3356 C CG . LYS C 3 57 ? 2.588 26.023 -27.466 1.00 29.81 ? 55 LYS C CG 1 ATOM 3357 C CD . LYS C 3 57 ? 1.639 24.895 -27.910 1.00 30.64 ? 55 LYS C CD 1 ATOM 3358 C CE . LYS C 3 57 ? 1.907 24.460 -29.362 1.00 30.72 ? 55 LYS C CE 1 ATOM 3359 N NZ . LYS C 3 57 ? 1.619 25.559 -30.344 1.00 30.14 ? 55 LYS C NZ 1 ATOM 3360 N N . THR C 3 58 ? 2.245 28.923 -23.895 1.00 29.22 ? 56 THR C N 1 ATOM 3361 C CA . THR C 3 58 ? 1.637 29.349 -22.622 1.00 29.84 ? 56 THR C CA 1 ATOM 3362 C C . THR C 3 58 ? 0.425 30.215 -22.913 1.00 31.16 ? 56 THR C C 1 ATOM 3363 O O . THR C 3 58 ? 0.258 30.702 -24.035 1.00 33.25 ? 56 THR C O 1 ATOM 3364 C CB . THR C 3 58 ? 2.583 30.228 -21.776 1.00 30.03 ? 56 THR C CB 1 ATOM 3365 O OG1 . THR C 3 58 ? 2.972 31.370 -22.547 1.00 31.06 ? 56 THR C OG1 1 ATOM 3366 C CG2 . THR C 3 58 ? 3.836 29.480 -21.306 1.00 29.40 ? 56 THR C CG2 1 ATOM 3367 N N . SER C 3 59 ? -0.406 30.431 -21.899 1.00 31.76 ? 57 SER C N 1 ATOM 3368 C CA . SER C 3 59 ? -1.580 31.304 -22.028 1.00 31.38 ? 57 SER C CA 1 ATOM 3369 C C . SER C 3 59 ? -1.896 32.013 -20.727 1.00 31.53 ? 57 SER C C 1 ATOM 3370 O O . SER C 3 59 ? -1.622 31.508 -19.640 1.00 31.76 ? 57 SER C O 1 ATOM 3371 C CB . SER C 3 59 ? -2.805 30.524 -22.505 1.00 30.97 ? 57 SER C CB 1 ATOM 3372 O OG . SER C 3 59 ? -2.981 29.353 -21.731 1.00 30.86 ? 57 SER C OG 1 ATOM 3373 N N . ASN C 3 60 ? -2.455 33.204 -20.851 1.00 32.72 ? 58 ASN C N 1 ATOM 3374 C CA . ASN C 3 60 ? -2.834 33.991 -19.706 1.00 33.43 ? 58 ASN C CA 1 ATOM 3375 C C . ASN C 3 60 ? -4.042 34.815 -20.098 1.00 34.04 ? 58 ASN C C 1 ATOM 3376 O O . ASN C 3 60 ? -3.921 35.956 -20.555 1.00 35.30 ? 58 ASN C O 1 ATOM 3377 C CB . ASN C 3 60 ? -1.664 34.862 -19.244 1.00 34.64 ? 58 ASN C CB 1 ATOM 3378 C CG . ASN C 3 60 ? -2.035 35.793 -18.093 1.00 37.80 ? 58 ASN C CG 1 ATOM 3379 O OD1 . ASN C 3 60 ? -3.170 35.777 -17.595 1.00 41.03 ? 58 ASN C OD1 1 ATOM 3380 N ND2 . ASN C 3 60 ? -1.078 36.620 -17.670 1.00 37.24 ? 58 ASN C ND2 1 ATOM 3381 N N . GLY C 3 61 ? -5.214 34.218 -19.932 1.00 33.60 ? 59 GLY C N 1 ATOM 3382 C CA . GLY C 3 61 ? -6.462 34.875 -20.285 1.00 33.32 ? 59 GLY C CA 1 ATOM 3383 C C . GLY C 3 61 ? -6.624 34.925 -21.784 1.00 32.65 ? 59 GLY C C 1 ATOM 3384 O O . GLY C 3 61 ? -6.638 33.896 -22.445 1.00 33.56 ? 59 GLY C O 1 ATOM 3385 N N . ARG C 3 62 ? -6.733 36.130 -22.322 1.00 32.77 ? 60 ARG C N 1 ATOM 3386 C CA . ARG C 3 62 ? -6.886 36.317 -23.763 1.00 33.27 ? 60 ARG C CA 1 ATOM 3387 C C . ARG C 3 62 ? -5.515 36.405 -24.459 1.00 31.15 ? 60 ARG C C 1 ATOM 3388 O O . ARG C 3 62 ? -5.432 36.544 -25.672 1.00 29.67 ? 60 ARG C O 1 ATOM 3389 C CB . ARG C 3 62 ? -7.731 37.561 -24.059 1.00 34.46 ? 60 ARG C CB 1 ATOM 3390 C CG . ARG C 3 62 ? -9.051 37.653 -23.281 1.00 35.04 ? 60 ARG C CG 1 ATOM 3391 C CD . ARG C 3 62 ? -9.849 38.878 -23.688 1.00 35.87 ? 60 ARG C CD 1 ATOM 3392 N NE . ARG C 3 62 ? -8.974 39.965 -24.141 1.00 38.78 ? 60 ARG C NE 1 ATOM 3393 C CZ . ARG C 3 62 ? -8.499 40.942 -23.366 1.00 38.73 ? 60 ARG C CZ 1 ATOM 3394 N NH1 . ARG C 3 62 ? -8.808 40.999 -22.073 1.00 39.18 ? 60 ARG C NH1 1 ATOM 3395 N NH2 . ARG C 3 62 ? -7.708 41.865 -23.891 1.00 36.82 ? 60 ARG C NH2 1 ATOM 3396 N N . TYR C 3 63 ? -4.450 36.314 -23.670 1.00 29.76 ? 61 TYR C N 1 ATOM 3397 C CA . TYR C 3 63 ? -3.090 36.268 -24.183 1.00 28.36 ? 61 TYR C CA 1 ATOM 3398 C C . TYR C 3 63 ? -2.644 34.816 -24.322 1.00 28.28 ? 61 TYR C C 1 ATOM 3399 O O . TYR C 3 63 ? -2.893 33.998 -23.434 1.00 29.01 ? 61 TYR C O 1 ATOM 3400 C CB . TYR C 3 63 ? -2.138 37.000 -23.228 1.00 27.88 ? 61 TYR C CB 1 ATOM 3401 C CG . TYR C 3 63 ? -2.481 38.458 -22.978 1.00 27.78 ? 61 TYR C CG 1 ATOM 3402 C CD1 . TYR C 3 63 ? -2.584 39.357 -24.036 1.00 28.11 ? 61 TYR C CD1 1 ATOM 3403 C CD2 . TYR C 3 63 ? -2.684 38.941 -21.691 1.00 27.16 ? 61 TYR C CD2 1 ATOM 3404 C CE1 . TYR C 3 63 ? -2.900 40.683 -23.827 1.00 28.30 ? 61 TYR C CE1 1 ATOM 3405 C CE2 . TYR C 3 63 ? -2.998 40.287 -21.471 1.00 27.52 ? 61 TYR C CE2 1 ATOM 3406 C CZ . TYR C 3 63 ? -3.102 41.149 -22.548 1.00 28.08 ? 61 TYR C CZ 1 ATOM 3407 O OH . TYR C 3 63 ? -3.405 42.486 -22.374 1.00 28.42 ? 61 TYR C OH 1 ATOM 3408 N N . SER C 3 64 ? -2.027 34.482 -25.450 1.00 26.73 ? 62 SER C N 1 ATOM 3409 C CA . SER C 3 64 ? -1.269 33.241 -25.542 1.00 26.10 ? 62 SER C CA 1 ATOM 3410 C C . SER C 3 64 ? 0.018 33.467 -26.331 1.00 26.90 ? 62 SER C C 1 ATOM 3411 O O . SER C 3 64 ? 0.182 34.500 -27.004 1.00 26.59 ? 62 SER C O 1 ATOM 3412 C CB . SER C 3 64 ? -2.086 32.081 -26.105 1.00 25.37 ? 62 SER C CB 1 ATOM 3413 O OG . SER C 3 64 ? -2.590 32.366 -27.390 1.00 25.37 ? 62 SER C OG 1 ATOM 3414 N N . ALA C 3 65 ? 0.934 32.510 -26.222 1.00 25.15 ? 63 ALA C N 1 ATOM 3415 C CA . ALA C 3 65 ? 2.256 32.682 -26.755 1.00 24.41 ? 63 ALA C CA 1 ATOM 3416 C C . ALA C 3 65 ? 2.911 31.337 -27.054 1.00 25.07 ? 63 ALA C C 1 ATOM 3417 O O . ALA C 3 65 ? 2.671 30.342 -26.361 1.00 24.43 ? 63 ALA C O 1 ATOM 3418 C CB . ALA C 3 65 ? 3.109 33.490 -25.774 1.00 23.65 ? 63 ALA C CB 1 ATOM 3419 N N . THR C 3 66 ? 3.747 31.328 -28.088 1.00 25.38 ? 64 THR C N 1 ATOM 3420 C CA . THR C 3 66 ? 4.613 30.203 -28.376 1.00 26.16 ? 64 THR C CA 1 ATOM 3421 C C . THR C 3 66 ? 6.067 30.672 -28.397 1.00 27.19 ? 64 THR C C 1 ATOM 3422 O O . THR C 3 66 ? 6.358 31.847 -28.653 1.00 27.32 ? 64 THR C O 1 ATOM 3423 C CB . THR C 3 66 ? 4.308 29.602 -29.754 1.00 26.02 ? 64 THR C CB 1 ATOM 3424 O OG1 . THR C 3 66 ? 4.483 30.620 -30.744 1.00 27.46 ? 64 THR C OG1 1 ATOM 3425 C CG2 . THR C 3 66 ? 2.902 29.094 -29.816 1.00 25.26 ? 64 THR C CG2 1 ATOM 3426 N N . LEU C 3 67 ? 6.978 29.743 -28.145 1.00 26.92 ? 65 LEU C N 1 ATOM 3427 C CA . LEU C 3 67 ? 8.391 29.995 -28.335 1.00 26.04 ? 65 LEU C CA 1 ATOM 3428 C C . LEU C 3 67 ? 8.998 28.781 -28.981 1.00 26.55 ? 65 LEU C C 1 ATOM 3429 O O . LEU C 3 67 ? 8.722 27.649 -28.563 1.00 27.02 ? 65 LEU C O 1 ATOM 3430 C CB . LEU C 3 67 ? 9.078 30.250 -26.995 1.00 25.45 ? 65 LEU C CB 1 ATOM 3431 C CG . LEU C 3 67 ? 10.607 30.152 -26.978 1.00 24.66 ? 65 LEU C CG 1 ATOM 3432 C CD1 . LEU C 3 67 ? 11.281 31.360 -27.651 1.00 23.20 ? 65 LEU C CD1 1 ATOM 3433 C CD2 . LEU C 3 67 ? 11.093 29.953 -25.554 1.00 24.43 ? 65 LEU C CD2 1 ATOM 3434 N N . ASP C 3 68 ? 9.824 29.021 -29.992 1.00 27.25 ? 66 ASP C N 1 ATOM 3435 C CA . ASP C 3 68 ? 10.599 27.973 -30.640 1.00 28.11 ? 66 ASP C CA 1 ATOM 3436 C C . ASP C 3 68 ? 12.069 28.404 -30.649 1.00 28.18 ? 66 ASP C C 1 ATOM 3437 O O . ASP C 3 68 ? 12.473 29.281 -31.424 1.00 27.16 ? 66 ASP C O 1 ATOM 3438 C CB . ASP C 3 68 ? 10.063 27.741 -32.050 1.00 30.22 ? 66 ASP C CB 1 ATOM 3439 C CG . ASP C 3 68 ? 10.897 26.757 -32.862 1.00 34.23 ? 66 ASP C CG 1 ATOM 3440 O OD1 . ASP C 3 68 ? 11.766 26.029 -32.309 1.00 36.11 ? 66 ASP C OD1 1 ATOM 3441 O OD2 . ASP C 3 68 ? 10.658 26.707 -34.090 1.00 36.32 ? 66 ASP C OD2 1 ATOM 3442 N N . LYS C 3 69 ? 12.857 27.776 -29.775 1.00 28.17 ? 67 LYS C N 1 ATOM 3443 C CA . LYS C 3 69 ? 14.263 28.132 -29.579 1.00 28.30 ? 67 LYS C CA 1 ATOM 3444 C C . LYS C 3 69 ? 15.201 27.781 -30.731 1.00 29.28 ? 67 LYS C C 1 ATOM 3445 O O . LYS C 3 69 ? 16.165 28.494 -30.961 1.00 32.30 ? 67 LYS C O 1 ATOM 3446 C CB . LYS C 3 69 ? 14.791 27.536 -28.279 1.00 28.12 ? 67 LYS C CB 1 ATOM 3447 C CG . LYS C 3 69 ? 14.328 28.273 -27.045 1.00 27.54 ? 67 LYS C CG 1 ATOM 3448 C CD . LYS C 3 69 ? 15.163 27.927 -25.843 1.00 25.94 ? 67 LYS C CD 1 ATOM 3449 C CE . LYS C 3 69 ? 14.353 28.143 -24.583 1.00 25.28 ? 67 LYS C CE 1 ATOM 3450 N NZ . LYS C 3 69 ? 15.081 27.694 -23.386 1.00 24.48 ? 67 LYS C NZ 1 ATOM 3451 N N . ASP C 3 70 ? 14.942 26.692 -31.443 1.00 29.96 ? 68 ASP C N 1 ATOM 3452 C CA . ASP C 3 70 ? 15.726 26.353 -32.633 1.00 30.99 ? 68 ASP C CA 1 ATOM 3453 C C . ASP C 3 70 ? 15.587 27.431 -33.707 1.00 31.22 ? 68 ASP C C 1 ATOM 3454 O O . ASP C 3 70 ? 16.556 27.767 -34.395 1.00 32.94 ? 68 ASP C O 1 ATOM 3455 C CB . ASP C 3 70 ? 15.284 25.005 -33.201 1.00 33.70 ? 68 ASP C CB 1 ATOM 3456 C CG . ASP C 3 70 ? 15.365 23.893 -32.177 1.00 37.31 ? 68 ASP C CG 1 ATOM 3457 O OD1 . ASP C 3 70 ? 14.310 23.421 -31.705 1.00 38.94 ? 68 ASP C OD1 1 ATOM 3458 O OD2 . ASP C 3 70 ? 16.495 23.505 -31.819 1.00 41.70 ? 68 ASP C OD2 1 ATOM 3459 N N . ALA C 3 71 ? 14.378 27.974 -33.845 1.00 28.31 ? 69 ALA C N 1 ATOM 3460 C CA . ALA C 3 71 ? 14.133 29.044 -34.790 1.00 25.66 ? 69 ALA C CA 1 ATOM 3461 C C . ALA C 3 71 ? 14.480 30.402 -34.194 1.00 25.09 ? 69 ALA C C 1 ATOM 3462 O O . ALA C 3 71 ? 14.509 31.399 -34.902 1.00 24.39 ? 69 ALA C O 1 ATOM 3463 C CB . ALA C 3 71 ? 12.694 29.013 -35.232 1.00 24.97 ? 69 ALA C CB 1 ATOM 3464 N N . LYS C 3 72 ? 14.753 30.429 -32.890 1.00 25.87 ? 70 LYS C N 1 ATOM 3465 C CA . LYS C 3 72 ? 14.861 31.670 -32.113 1.00 25.60 ? 70 LYS C CA 1 ATOM 3466 C C . LYS C 3 72 ? 13.713 32.592 -32.506 1.00 25.27 ? 70 LYS C C 1 ATOM 3467 O O . LYS C 3 72 ? 13.905 33.624 -33.133 1.00 25.56 ? 70 LYS C O 1 ATOM 3468 C CB . LYS C 3 72 ? 16.233 32.340 -32.287 1.00 26.00 ? 70 LYS C CB 1 ATOM 3469 C CG . LYS C 3 72 ? 17.395 31.369 -32.098 1.00 28.30 ? 70 LYS C CG 1 ATOM 3470 C CD . LYS C 3 72 ? 18.567 31.967 -31.320 1.00 29.30 ? 70 LYS C CD 1 ATOM 3471 C CE . LYS C 3 72 ? 19.274 30.875 -30.523 1.00 31.67 ? 70 LYS C CE 1 ATOM 3472 N NZ . LYS C 3 72 ? 20.430 31.378 -29.687 1.00 32.77 ? 70 LYS C NZ 1 ATOM 3473 N N . HIS C 3 73 ? 12.505 32.184 -32.143 1.00 25.33 ? 71 HIS C N 1 ATOM 3474 C CA . HIS C 3 73 ? 11.300 32.875 -32.570 1.00 24.85 ? 71 HIS C CA 1 ATOM 3475 C C . HIS C 3 73 ? 10.184 32.690 -31.584 1.00 24.08 ? 71 HIS C C 1 ATOM 3476 O O . HIS C 3 73 ? 9.938 31.578 -31.121 1.00 24.59 ? 71 HIS C O 1 ATOM 3477 C CB . HIS C 3 73 ? 10.891 32.348 -33.947 1.00 25.11 ? 71 HIS C CB 1 ATOM 3478 C CG . HIS C 3 73 ? 9.590 32.898 -34.445 1.00 24.38 ? 71 HIS C CG 1 ATOM 3479 N ND1 . HIS C 3 73 ? 9.479 34.140 -34.938 1.00 24.68 ? 71 HIS C ND1 1 ATOM 3480 C CD2 . HIS C 3 73 ? 8.321 32.332 -34.500 1.00 24.32 ? 71 HIS C CD2 1 ATOM 3481 C CE1 . HIS C 3 73 ? 8.198 34.364 -35.298 1.00 25.19 ? 71 HIS C CE1 1 ATOM 3482 N NE2 . HIS C 3 73 ? 7.490 33.256 -35.023 1.00 24.58 ? 71 HIS C NE2 1 ATOM 3483 N N . SER C 3 74 ? 9.488 33.778 -31.270 1.00 23.71 ? 72 SER C N 1 ATOM 3484 C CA . SER C 3 74 ? 8.317 33.739 -30.391 1.00 23.81 ? 72 SER C CA 1 ATOM 3485 C C . SER C 3 74 ? 7.191 34.592 -30.951 1.00 23.95 ? 72 SER C C 1 ATOM 3486 O O . SER C 3 74 ? 7.456 35.519 -31.703 1.00 25.35 ? 72 SER C O 1 ATOM 3487 C CB . SER C 3 74 ? 8.690 34.255 -29.007 1.00 24.20 ? 72 SER C CB 1 ATOM 3488 O OG . SER C 3 74 ? 7.583 34.226 -28.128 1.00 23.91 ? 72 SER C OG 1 ATOM 3489 N N . THR C 3 75 ? 5.946 34.272 -30.596 1.00 24.12 ? 73 THR C N 1 ATOM 3490 C CA . THR C 3 75 ? 4.781 35.103 -30.945 1.00 24.38 ? 73 THR C CA 1 ATOM 3491 C C . THR C 3 75 ? 3.831 35.330 -29.757 1.00 24.53 ? 73 THR C C 1 ATOM 3492 O O . THR C 3 75 ? 3.750 34.503 -28.855 1.00 24.75 ? 73 THR C O 1 ATOM 3493 C CB . THR C 3 75 ? 3.918 34.471 -32.049 1.00 25.21 ? 73 THR C CB 1 ATOM 3494 O OG1 . THR C 3 75 ? 3.313 33.267 -31.545 1.00 26.87 ? 73 THR C OG1 1 ATOM 3495 C CG2 . THR C 3 75 ? 4.728 34.183 -33.300 1.00 24.67 ? 73 THR C CG2 1 ATOM 3496 N N . LEU C 3 76 ? 3.105 36.444 -29.778 1.00 24.03 ? 74 LEU C N 1 ATOM 3497 C CA . LEU C 3 76 ? 2.097 36.730 -28.775 1.00 24.14 ? 74 LEU C CA 1 ATOM 3498 C C . LEU C 3 76 ? 0.756 36.974 -29.472 1.00 25.60 ? 74 LEU C C 1 ATOM 3499 O O . LEU C 3 76 ? 0.628 37.859 -30.323 1.00 24.80 ? 74 LEU C O 1 ATOM 3500 C CB . LEU C 3 76 ? 2.511 37.919 -27.886 1.00 22.70 ? 74 LEU C CB 1 ATOM 3501 C CG . LEU C 3 76 ? 1.526 38.442 -26.822 1.00 21.66 ? 74 LEU C CG 1 ATOM 3502 C CD1 . LEU C 3 76 ? 1.322 37.461 -25.671 1.00 21.83 ? 74 LEU C CD1 1 ATOM 3503 C CD2 . LEU C 3 76 ? 1.972 39.751 -26.260 1.00 21.24 ? 74 LEU C CD2 1 ATOM 3504 N N . HIS C 3 77 ? -0.224 36.147 -29.120 1.00 28.40 ? 75 HIS C N 1 ATOM 3505 C CA . HIS C 3 77 ? -1.558 36.217 -29.676 1.00 30.31 ? 75 HIS C CA 1 ATOM 3506 C C . HIS C 3 77 ? -2.431 36.871 -28.654 1.00 29.77 ? 75 HIS C C 1 ATOM 3507 O O . HIS C 3 77 ? -2.500 36.420 -27.503 1.00 29.44 ? 75 HIS C O 1 ATOM 3508 C CB . HIS C 3 77 ? -2.090 34.815 -29.991 1.00 34.91 ? 75 HIS C CB 1 ATOM 3509 C CG . HIS C 3 77 ? -1.259 34.040 -31.006 1.00 44.26 ? 75 HIS C CG 1 ATOM 3510 N ND1 . HIS C 3 77 ? -1.736 33.690 -32.227 1.00 47.69 ? 75 HIS C ND1 1 ATOM 3511 C CD2 . HIS C 3 77 ? 0.060 33.536 -30.941 1.00 47.39 ? 75 HIS C CD2 1 ATOM 3512 C CE1 . HIS C 3 77 ? -0.777 33.007 -32.912 1.00 46.49 ? 75 HIS C CE1 1 ATOM 3513 N NE2 . HIS C 3 77 ? 0.318 32.916 -32.125 1.00 47.95 ? 75 HIS C NE2 1 ATOM 3514 N N . ILE C 3 78 ? -3.087 37.955 -29.056 1.00 28.66 ? 76 ILE C N 1 ATOM 3515 C CA . ILE C 3 78 ? -4.141 38.571 -28.254 1.00 28.25 ? 76 ILE C CA 1 ATOM 3516 C C . ILE C 3 78 ? -5.479 38.223 -28.887 1.00 28.55 ? 76 ILE C C 1 ATOM 3517 O O . ILE C 3 78 ? -5.679 38.470 -30.064 1.00 32.20 ? 76 ILE C O 1 ATOM 3518 C CB . ILE C 3 78 ? -3.967 40.091 -28.186 1.00 27.96 ? 76 ILE C CB 1 ATOM 3519 C CG1 . ILE C 3 78 ? -2.559 40.427 -27.676 1.00 27.93 ? 76 ILE C CG1 1 ATOM 3520 C CG2 . ILE C 3 78 ? -5.028 40.706 -27.296 1.00 27.68 ? 76 ILE C CG2 1 ATOM 3521 C CD1 . ILE C 3 78 ? -2.231 41.902 -27.651 1.00 28.05 ? 76 ILE C CD1 1 ATOM 3522 N N . THR C 3 79 ? -6.379 37.617 -28.127 1.00 28.93 ? 77 THR C N 1 ATOM 3523 C CA . THR C 3 79 ? -7.693 37.235 -28.646 1.00 29.62 ? 77 THR C CA 1 ATOM 3524 C C . THR C 3 79 ? -8.750 38.270 -28.274 1.00 30.89 ? 77 THR C C 1 ATOM 3525 O O . THR C 3 79 ? -8.769 38.762 -27.131 1.00 32.23 ? 77 THR C O 1 ATOM 3526 C CB . THR C 3 79 ? -8.138 35.864 -28.113 1.00 29.47 ? 77 THR C CB 1 ATOM 3527 O OG1 . THR C 3 79 ? -7.195 34.871 -28.526 1.00 30.07 ? 77 THR C OG1 1 ATOM 3528 C CG2 . THR C 3 79 ? -9.513 35.490 -28.664 1.00 28.93 ? 77 THR C CG2 1 ATOM 3529 N N . ALA C 3 80 ? -9.617 38.604 -29.234 1.00 29.56 ? 78 ALA C N 1 ATOM 3530 C CA . ALA C 3 80 ? -10.743 39.506 -28.987 1.00 29.35 ? 78 ALA C CA 1 ATOM 3531 C C . ALA C 3 80 ? -10.292 40.804 -28.297 1.00 29.99 ? 78 ALA C C 1 ATOM 3532 O O . ALA C 3 80 ? -10.640 41.062 -27.131 1.00 31.75 ? 78 ALA C O 1 ATOM 3533 C CB . ALA C 3 80 ? -11.824 38.786 -28.160 1.00 27.94 ? 78 ALA C CB 1 ATOM 3534 N N . THR C 3 81 ? -9.515 41.613 -29.014 1.00 28.43 ? 79 THR C N 1 ATOM 3535 C CA . THR C 3 81 ? -8.860 42.765 -28.412 1.00 28.96 ? 79 THR C CA 1 ATOM 3536 C C . THR C 3 81 ? -9.862 43.706 -27.774 1.00 28.94 ? 79 THR C C 1 ATOM 3537 O O . THR C 3 81 ? -10.930 43.970 -28.337 1.00 28.97 ? 79 THR C O 1 ATOM 3538 C CB . THR C 3 81 ? -8.056 43.552 -29.442 1.00 31.00 ? 79 THR C CB 1 ATOM 3539 O OG1 . THR C 3 81 ? -8.840 43.697 -30.634 1.00 33.56 ? 79 THR C OG1 1 ATOM 3540 C CG2 . THR C 3 81 ? -6.755 42.839 -29.786 1.00 30.57 ? 79 THR C CG2 1 ATOM 3541 N N . LEU C 3 82 ? -9.518 44.188 -26.584 1.00 28.92 ? 80 LEU C N 1 ATOM 3542 C CA . LEU C 3 82 ? -10.291 45.213 -25.887 1.00 28.07 ? 80 LEU C CA 1 ATOM 3543 C C . LEU C 3 82 ? -9.541 46.525 -25.973 1.00 28.47 ? 80 LEU C C 1 ATOM 3544 O O . LEU C 3 82 ? -8.368 46.549 -26.320 1.00 27.61 ? 80 LEU C O 1 ATOM 3545 C CB . LEU C 3 82 ? -10.480 44.845 -24.418 1.00 28.09 ? 80 LEU C CB 1 ATOM 3546 C CG . LEU C 3 82 ? -11.313 43.610 -24.051 1.00 27.66 ? 80 LEU C CG 1 ATOM 3547 C CD1 . LEU C 3 82 ? -11.346 43.446 -22.539 1.00 25.81 ? 80 LEU C CD1 1 ATOM 3548 C CD2 . LEU C 3 82 ? -12.736 43.682 -24.648 1.00 26.95 ? 80 LEU C CD2 1 ATOM 3549 N N . LEU C 3 83 ? -10.225 47.617 -25.653 1.00 30.61 ? 81 LEU C N 1 ATOM 3550 C CA . LEU C 3 83 ? -9.649 48.951 -25.732 1.00 29.94 ? 81 LEU C CA 1 ATOM 3551 C C . LEU C 3 83 ? -8.386 49.077 -24.855 1.00 30.94 ? 81 LEU C C 1 ATOM 3552 O O . LEU C 3 83 ? -7.391 49.670 -25.286 1.00 30.19 ? 81 LEU C O 1 ATOM 3553 C CB . LEU C 3 83 ? -10.722 50.000 -25.398 1.00 30.05 ? 81 LEU C CB 1 ATOM 3554 C CG . LEU C 3 83 ? -10.364 51.441 -24.995 1.00 31.29 ? 81 LEU C CG 1 ATOM 3555 C CD1 . LEU C 3 83 ? -9.496 52.189 -26.038 1.00 32.26 ? 81 LEU C CD1 1 ATOM 3556 C CD2 . LEU C 3 83 ? -11.631 52.236 -24.683 1.00 30.87 ? 81 LEU C CD2 1 ATOM 3557 N N . ASP C 3 84 ? -8.424 48.483 -23.655 1.00 32.39 ? 82 ASP C N 1 ATOM 3558 C CA . ASP C 3 84 ? -7.289 48.471 -22.704 1.00 32.57 ? 82 ASP C CA 1 ATOM 3559 C C . ASP C 3 84 ? -6.035 47.757 -23.195 1.00 31.56 ? 82 ASP C C 1 ATOM 3560 O O . ASP C 3 84 ? -4.962 47.910 -22.603 1.00 32.24 ? 82 ASP C O 1 ATOM 3561 C CB . ASP C 3 84 ? -7.708 47.872 -21.358 1.00 36.57 ? 82 ASP C CB 1 ATOM 3562 C CG . ASP C 3 84 ? -8.572 48.825 -20.540 1.00 43.13 ? 82 ASP C CG 1 ATOM 3563 O OD1 . ASP C 3 84 ? -8.420 50.065 -20.714 1.00 43.74 ? 82 ASP C OD1 1 ATOM 3564 O OD2 . ASP C 3 84 ? -9.404 48.335 -19.731 1.00 44.65 ? 82 ASP C OD2 1 ATOM 3565 N N . ASP C 3 85 ? -6.167 46.978 -24.267 1.00 29.90 ? 83 ASP C N 1 ATOM 3566 C CA . ASP C 3 85 ? -5.022 46.353 -24.908 1.00 28.48 ? 83 ASP C CA 1 ATOM 3567 C C . ASP C 3 85 ? -4.091 47.364 -25.572 1.00 27.67 ? 83 ASP C C 1 ATOM 3568 O O . ASP C 3 85 ? -2.953 47.035 -25.880 1.00 29.15 ? 83 ASP C O 1 ATOM 3569 C CB . ASP C 3 85 ? -5.483 45.321 -25.920 1.00 29.76 ? 83 ASP C CB 1 ATOM 3570 C CG . ASP C 3 85 ? -6.018 44.067 -25.263 1.00 32.06 ? 83 ASP C CG 1 ATOM 3571 O OD1 . ASP C 3 85 ? -5.464 43.673 -24.216 1.00 35.15 ? 83 ASP C OD1 1 ATOM 3572 O OD2 . ASP C 3 85 ? -6.973 43.455 -25.797 1.00 32.32 ? 83 ASP C OD2 1 ATOM 3573 N N . THR C 3 86 ? -4.571 48.585 -25.791 1.00 25.47 ? 84 THR C N 1 ATOM 3574 C CA . THR C 3 86 ? -3.752 49.662 -26.344 1.00 24.86 ? 84 THR C CA 1 ATOM 3575 C C . THR C 3 86 ? -2.507 49.882 -25.468 1.00 25.80 ? 84 THR C C 1 ATOM 3576 O O . THR C 3 86 ? -2.605 50.331 -24.312 1.00 26.24 ? 84 THR C O 1 ATOM 3577 C CB . THR C 3 86 ? -4.575 50.985 -26.465 1.00 23.77 ? 84 THR C CB 1 ATOM 3578 O OG1 . THR C 3 86 ? -5.804 50.721 -27.149 1.00 22.97 ? 84 THR C OG1 1 ATOM 3579 C CG2 . THR C 3 86 ? -3.813 52.042 -27.215 1.00 21.93 ? 84 THR C CG2 1 ATOM 3580 N N . ALA C 3 87 ? -1.342 49.562 -26.029 1.00 25.15 ? 85 ALA C N 1 ATOM 3581 C CA . ALA C 3 87 ? -0.096 49.541 -25.271 1.00 24.49 ? 85 ALA C CA 1 ATOM 3582 C C . ALA C 3 87 ? 1.094 49.203 -26.177 1.00 25.10 ? 85 ALA C C 1 ATOM 3583 O O . ALA C 3 87 ? 0.925 48.856 -27.352 1.00 25.53 ? 85 ALA C O 1 ATOM 3584 C CB . ALA C 3 87 ? -0.199 48.529 -24.132 1.00 23.81 ? 85 ALA C CB 1 ATOM 3585 N N . THR C 3 88 ? 2.299 49.332 -25.632 1.00 24.40 ? 86 THR C N 1 ATOM 3586 C CA . THR C 3 88 ? 3.485 48.827 -26.287 1.00 24.03 ? 86 THR C CA 1 ATOM 3587 C C . THR C 3 88 ? 3.761 47.449 -25.699 1.00 23.51 ? 86 THR C C 1 ATOM 3588 O O . THR C 3 88 ? 3.666 47.256 -24.489 1.00 23.18 ? 86 THR C O 1 ATOM 3589 C CB . THR C 3 88 ? 4.682 49.772 -26.079 1.00 24.94 ? 86 THR C CB 1 ATOM 3590 O OG1 . THR C 3 88 ? 4.522 50.934 -26.905 1.00 25.82 ? 86 THR C OG1 1 ATOM 3591 C CG2 . THR C 3 88 ? 6.008 49.088 -26.424 1.00 24.39 ? 86 THR C CG2 1 ATOM 3592 N N . TYR C 3 89 ? 4.071 46.491 -26.564 1.00 23.37 ? 87 TYR C N 1 ATOM 3593 C CA . TYR C 3 89 ? 4.329 45.118 -26.146 1.00 23.50 ? 87 TYR C CA 1 ATOM 3594 C C . TYR C 3 89 ? 5.785 44.779 -26.351 1.00 23.46 ? 87 TYR C C 1 ATOM 3595 O O . TYR C 3 89 ? 6.306 44.917 -27.459 1.00 23.47 ? 87 TYR C O 1 ATOM 3596 C CB . TYR C 3 89 ? 3.413 44.158 -26.892 1.00 23.58 ? 87 TYR C CB 1 ATOM 3597 C CG . TYR C 3 89 ? 1.994 44.283 -26.418 1.00 23.51 ? 87 TYR C CG 1 ATOM 3598 C CD1 . TYR C 3 89 ? 1.150 45.282 -26.919 1.00 23.17 ? 87 TYR C CD1 1 ATOM 3599 C CD2 . TYR C 3 89 ? 1.508 43.436 -25.429 1.00 23.64 ? 87 TYR C CD2 1 ATOM 3600 C CE1 . TYR C 3 89 ? -0.149 45.411 -26.460 1.00 23.47 ? 87 TYR C CE1 1 ATOM 3601 C CE2 . TYR C 3 89 ? 0.216 43.556 -24.960 1.00 24.50 ? 87 TYR C CE2 1 ATOM 3602 C CZ . TYR C 3 89 ? -0.607 44.542 -25.478 1.00 24.64 ? 87 TYR C CZ 1 ATOM 3603 O OH . TYR C 3 89 ? -1.893 44.631 -24.992 1.00 26.76 ? 87 TYR C OH 1 ATOM 3604 N N . ILE C 3 90 ? 6.434 44.359 -25.267 1.00 23.41 ? 88 ILE C N 1 ATOM 3605 C CA . ILE C 3 90 ? 7.886 44.248 -25.223 1.00 23.53 ? 88 ILE C CA 1 ATOM 3606 C C . ILE C 3 90 ? 8.346 42.815 -25.009 1.00 24.25 ? 88 ILE C C 1 ATOM 3607 O O . ILE C 3 90 ? 7.915 42.121 -24.081 1.00 24.21 ? 88 ILE C O 1 ATOM 3608 C CB . ILE C 3 90 ? 8.511 45.185 -24.141 1.00 23.39 ? 88 ILE C CB 1 ATOM 3609 C CG1 . ILE C 3 90 ? 8.243 46.652 -24.479 1.00 22.98 ? 88 ILE C CG1 1 ATOM 3610 C CG2 . ILE C 3 90 ? 10.019 44.960 -24.015 1.00 23.55 ? 88 ILE C CG2 1 ATOM 3611 C CD1 . ILE C 3 90 ? 8.949 47.632 -23.569 1.00 23.33 ? 88 ILE C CD1 1 ATOM 3612 N N . CYS C 3 91 ? 9.246 42.401 -25.880 1.00 25.62 ? 89 CYS C N 1 ATOM 3613 C CA . CYS C 3 91 ? 9.817 41.076 -25.855 1.00 27.74 ? 89 CYS C CA 1 ATOM 3614 C C . CYS C 3 91 ? 11.166 41.101 -25.126 1.00 26.52 ? 89 CYS C C 1 ATOM 3615 O O . CYS C 3 91 ? 12.020 41.921 -25.439 1.00 27.31 ? 89 CYS C O 1 ATOM 3616 C CB . CYS C 3 91 ? 9.996 40.616 -27.306 1.00 31.24 ? 89 CYS C CB 1 ATOM 3617 S SG . CYS C 3 91 ? 10.598 38.957 -27.484 1.00 37.25 ? 89 CYS C SG 1 ATOM 3618 N N . VAL C 3 92 ? 11.370 40.209 -24.162 1.00 24.61 ? 90 VAL C N 1 ATOM 3619 C CA . VAL C 3 92 ? 12.642 40.181 -23.432 1.00 23.56 ? 90 VAL C CA 1 ATOM 3620 C C . VAL C 3 92 ? 13.249 38.772 -23.324 1.00 22.76 ? 90 VAL C C 1 ATOM 3621 O O . VAL C 3 92 ? 12.588 37.840 -22.870 1.00 22.60 ? 90 VAL C O 1 ATOM 3622 C CB . VAL C 3 92 ? 12.478 40.807 -22.024 1.00 23.89 ? 90 VAL C CB 1 ATOM 3623 C CG1 . VAL C 3 92 ? 13.839 41.083 -21.375 1.00 23.43 ? 90 VAL C CG1 1 ATOM 3624 C CG2 . VAL C 3 92 ? 11.667 42.094 -22.103 1.00 23.41 ? 90 VAL C CG2 1 ATOM 3625 N N . VAL C 3 93 ? 14.507 38.624 -23.740 1.00 21.81 ? 91 VAL C N 1 ATOM 3626 C CA . VAL C 3 93 ? 15.192 37.326 -23.679 1.00 21.33 ? 91 VAL C CA 1 ATOM 3627 C C . VAL C 3 93 ? 16.293 37.348 -22.615 1.00 21.24 ? 91 VAL C C 1 ATOM 3628 O O . VAL C 3 93 ? 17.114 38.269 -22.582 1.00 20.58 ? 91 VAL C O 1 ATOM 3629 C CB . VAL C 3 93 ? 15.793 36.898 -25.069 1.00 21.34 ? 91 VAL C CB 1 ATOM 3630 C CG1 . VAL C 3 93 ? 16.678 35.644 -24.936 1.00 20.32 ? 91 VAL C CG1 1 ATOM 3631 C CG2 . VAL C 3 93 ? 14.688 36.658 -26.096 1.00 20.65 ? 91 VAL C CG2 1 ATOM 3632 N N . GLY C 3 94 ? 16.288 36.339 -21.743 1.00 21.49 ? 92 GLY C N 1 ATOM 3633 C CA . GLY C 3 94 ? 17.285 36.211 -20.675 1.00 21.72 ? 92 GLY C CA 1 ATOM 3634 C C . GLY C 3 94 ? 18.278 35.125 -21.018 1.00 22.47 ? 92 GLY C C 1 ATOM 3635 O O . GLY C 3 94 ? 17.879 34.018 -21.395 1.00 21.86 ? 92 GLY C O 1 ATOM 3636 N N . ASP C 3 95 ? 19.572 35.433 -20.890 1.00 23.04 ? 93 ASP C N 1 ATOM 3637 C CA . ASP C 3 95 ? 20.628 34.487 -21.292 1.00 22.73 ? 93 ASP C CA 1 ATOM 3638 C C . ASP C 3 95 ? 21.093 33.490 -20.200 1.00 21.84 ? 93 ASP C C 1 ATOM 3639 O O . ASP C 3 95 ? 22.009 32.707 -20.422 1.00 21.27 ? 93 ASP C O 1 ATOM 3640 C CB . ASP C 3 95 ? 21.808 35.220 -21.960 1.00 23.82 ? 93 ASP C CB 1 ATOM 3641 C CG . ASP C 3 95 ? 22.433 36.307 -21.073 1.00 25.81 ? 93 ASP C CG 1 ATOM 3642 O OD1 . ASP C 3 95 ? 22.362 36.202 -19.825 1.00 25.53 ? 93 ASP C OD1 1 ATOM 3643 O OD2 . ASP C 3 95 ? 23.023 37.270 -21.637 1.00 26.22 ? 93 ASP C OD2 1 ATOM 3644 N N . ARG C 3 96 ? 20.440 33.512 -19.042 1.00 21.23 ? 94 ARG C N 1 ATOM 3645 C CA . ARG C 3 96 ? 20.750 32.588 -17.960 1.00 21.78 ? 94 ARG C CA 1 ATOM 3646 C C . ARG C 3 96 ? 19.520 32.198 -17.169 1.00 22.27 ? 94 ARG C C 1 ATOM 3647 O O . ARG C 3 96 ? 18.608 33.008 -16.998 1.00 23.18 ? 94 ARG C O 1 ATOM 3648 C CB . ARG C 3 96 ? 21.753 33.198 -16.974 1.00 21.61 ? 94 ARG C CB 1 ATOM 3649 C CG . ARG C 3 96 ? 23.165 33.400 -17.509 1.00 21.63 ? 94 ARG C CG 1 ATOM 3650 C CD . ARG C 3 96 ? 23.947 32.095 -17.707 1.00 21.43 ? 94 ARG C CD 1 ATOM 3651 N NE . ARG C 3 96 ? 25.338 32.398 -18.013 1.00 21.36 ? 94 ARG C NE 1 ATOM 3652 C CZ . ARG C 3 96 ? 25.750 32.964 -19.144 1.00 21.73 ? 94 ARG C CZ 1 ATOM 3653 N NH1 . ARG C 3 96 ? 27.027 33.222 -19.324 1.00 21.99 ? 94 ARG C NH1 1 ATOM 3654 N NH2 . ARG C 3 96 ? 24.889 33.295 -20.094 1.00 22.01 ? 94 ARG C NH2 1 ATOM 3655 N N . GLY C 3 97 ? 19.516 30.970 -16.654 1.00 21.70 ? 95 GLY C N 1 ATOM 3656 C CA . GLY C 3 97 ? 18.516 30.566 -15.676 1.00 22.05 ? 95 GLY C CA 1 ATOM 3657 C C . GLY C 3 97 ? 18.748 31.030 -14.238 1.00 22.49 ? 95 GLY C C 1 ATOM 3658 O O . GLY C 3 97 ? 18.183 30.436 -13.302 1.00 22.24 ? 95 GLY C O 1 ATOM 3659 N N . SER C 3 98 ? 19.565 32.076 -14.064 1.00 21.87 ? 96 SER C N 1 ATOM 3660 C CA . SER C 3 98 ? 19.892 32.625 -12.754 1.00 22.71 ? 96 SER C CA 1 ATOM 3661 C C . SER C 3 98 ? 20.231 34.119 -12.826 1.00 23.99 ? 96 SER C C 1 ATOM 3662 O O . SER C 3 98 ? 20.244 34.724 -13.912 1.00 24.25 ? 96 SER C O 1 ATOM 3663 C CB . SER C 3 98 ? 21.097 31.912 -12.168 1.00 23.48 ? 96 SER C CB 1 ATOM 3664 O OG . SER C 3 98 ? 22.292 32.576 -12.577 1.00 24.04 ? 96 SER C OG 1 ATOM 3665 N N . ALA C 3 99 ? 20.552 34.697 -11.665 1.00 23.81 ? 97 ALA C N 1 ATOM 3666 C CA . ALA C 3 99 ? 20.818 36.126 -11.561 1.00 23.37 ? 97 ALA C CA 1 ATOM 3667 C C . ALA C 3 99 ? 22.076 36.555 -12.302 1.00 23.26 ? 97 ALA C C 1 ATOM 3668 O O . ALA C 3 99 ? 22.304 37.743 -12.457 1.00 23.80 ? 97 ALA C O 1 ATOM 3669 C CB . ALA C 3 99 ? 20.896 36.538 -10.120 1.00 23.72 ? 97 ALA C CB 1 ATOM 3670 N N . LEU C 3 100 ? 22.882 35.590 -12.748 1.00 22.99 ? 98 LEU C N 1 ATOM 3671 C CA . LEU C 3 100 ? 24.097 35.860 -13.517 1.00 22.63 ? 98 LEU C CA 1 ATOM 3672 C C . LEU C 3 100 ? 23.811 36.362 -14.932 1.00 23.24 ? 98 LEU C C 1 ATOM 3673 O O . LEU C 3 100 ? 24.711 36.860 -15.619 1.00 23.98 ? 98 LEU C O 1 ATOM 3674 C CB . LEU C 3 100 ? 24.970 34.610 -13.579 1.00 22.58 ? 98 LEU C CB 1 ATOM 3675 C CG . LEU C 3 100 ? 25.623 34.203 -12.257 1.00 22.83 ? 98 LEU C CG 1 ATOM 3676 C CD1 . LEU C 3 100 ? 26.608 33.089 -12.481 1.00 22.35 ? 98 LEU C CD1 1 ATOM 3677 C CD2 . LEU C 3 100 ? 26.327 35.394 -11.618 1.00 23.77 ? 98 LEU C CD2 1 ATOM 3678 N N . GLY C 3 101 ? 22.551 36.243 -15.349 1.00 23.25 ? 99 GLY C N 1 ATOM 3679 C CA . GLY C 3 101 ? 22.121 36.631 -16.678 1.00 22.73 ? 99 GLY C CA 1 ATOM 3680 C C . GLY C 3 101 ? 21.867 38.102 -16.925 1.00 23.06 ? 99 GLY C C 1 ATOM 3681 O O . GLY C 3 101 ? 21.571 38.880 -16.003 1.00 22.29 ? 99 GLY C O 1 ATOM 3682 N N . ARG C 3 102 ? 22.002 38.467 -18.198 1.00 23.31 ? 100 ARG C N 1 ATOM 3683 C CA . ARG C 3 102 ? 21.597 39.764 -18.708 1.00 23.43 ? 100 ARG C CA 1 ATOM 3684 C C . ARG C 3 102 ? 20.278 39.609 -19.450 1.00 22.84 ? 100 ARG C C 1 ATOM 3685 O O . ARG C 3 102 ? 20.033 38.575 -20.064 1.00 23.96 ? 100 ARG C O 1 ATOM 3686 C CB . ARG C 3 102 ? 22.660 40.318 -19.657 1.00 24.07 ? 100 ARG C CB 1 ATOM 3687 C CG . ARG C 3 102 ? 24.025 40.540 -19.025 1.00 25.92 ? 100 ARG C CG 1 ATOM 3688 C CD . ARG C 3 102 ? 24.035 41.723 -18.062 1.00 27.54 ? 100 ARG C CD 1 ATOM 3689 N NE . ARG C 3 102 ? 25.302 41.785 -17.330 1.00 29.14 ? 100 ARG C NE 1 ATOM 3690 C CZ . ARG C 3 102 ? 26.264 42.679 -17.543 1.00 28.81 ? 100 ARG C CZ 1 ATOM 3691 N NH1 . ARG C 3 102 ? 26.114 43.626 -18.467 1.00 28.22 ? 100 ARG C NH1 1 ATOM 3692 N NH2 . ARG C 3 102 ? 27.376 42.630 -16.812 1.00 28.16 ? 100 ARG C NH2 1 ATOM 3693 N N . LEU C 3 103 ? 19.429 40.632 -19.387 1.00 22.38 ? 101 LEU C N 1 ATOM 3694 C CA . LEU C 3 103 ? 18.189 40.659 -20.160 1.00 21.66 ? 101 LEU C CA 1 ATOM 3695 C C . LEU C 3 103 ? 18.385 41.504 -21.411 1.00 22.40 ? 101 LEU C C 1 ATOM 3696 O O . LEU C 3 103 ? 19.059 42.539 -21.373 1.00 23.36 ? 101 LEU C O 1 ATOM 3697 C CB . LEU C 3 103 ? 17.054 41.219 -19.314 1.00 20.70 ? 101 LEU C CB 1 ATOM 3698 C CG . LEU C 3 103 ? 16.711 40.545 -17.975 1.00 20.07 ? 101 LEU C CG 1 ATOM 3699 C CD1 . LEU C 3 103 ? 15.693 41.390 -17.204 1.00 19.55 ? 101 LEU C CD1 1 ATOM 3700 C CD2 . LEU C 3 103 ? 16.196 39.118 -18.164 1.00 18.87 ? 101 LEU C CD2 1 ATOM 3701 N N . HIS C 3 104 ? 17.804 41.058 -22.519 1.00 22.56 ? 102 HIS C N 1 ATOM 3702 C CA . HIS C 3 104 ? 17.971 41.723 -23.821 1.00 22.10 ? 102 HIS C CA 1 ATOM 3703 C C . HIS C 3 104 ? 16.623 42.120 -24.296 1.00 21.51 ? 102 HIS C C 1 ATOM 3704 O O . HIS C 3 104 ? 15.758 41.265 -24.544 1.00 22.05 ? 102 HIS C O 1 ATOM 3705 C CB . HIS C 3 104 ? 18.653 40.789 -24.825 1.00 23.06 ? 102 HIS C CB 1 ATOM 3706 C CG . HIS C 3 104 ? 19.945 40.182 -24.305 1.00 24.48 ? 102 HIS C CG 1 ATOM 3707 N ND1 . HIS C 3 104 ? 21.162 40.572 -24.741 1.00 24.81 ? 102 HIS C ND1 1 ATOM 3708 C CD2 . HIS C 3 104 ? 20.172 39.214 -23.324 1.00 24.46 ? 102 HIS C CD2 1 ATOM 3709 C CE1 . HIS C 3 104 ? 22.113 39.882 -24.089 1.00 24.67 ? 102 HIS C CE1 1 ATOM 3710 N NE2 . HIS C 3 104 ? 21.506 39.047 -23.224 1.00 24.81 ? 102 HIS C NE2 1 ATOM 3711 N N . PHE C 3 105 ? 16.414 43.427 -24.398 1.00 20.68 ? 103 PHE C N 1 ATOM 3712 C CA . PHE C 3 105 ? 15.077 43.982 -24.612 1.00 20.26 ? 103 PHE C CA 1 ATOM 3713 C C . PHE C 3 105 ? 14.791 44.315 -26.064 1.00 20.53 ? 103 PHE C C 1 ATOM 3714 O O . PHE C 3 105 ? 15.618 44.888 -26.758 1.00 22.01 ? 103 PHE C O 1 ATOM 3715 C CB . PHE C 3 105 ? 14.908 45.257 -23.791 1.00 19.30 ? 103 PHE C CB 1 ATOM 3716 C CG . PHE C 3 105 ? 14.725 45.026 -22.317 1.00 18.95 ? 103 PHE C CG 1 ATOM 3717 C CD1 . PHE C 3 105 ? 15.822 44.934 -21.469 1.00 19.05 ? 103 PHE C CD1 1 ATOM 3718 C CD2 . PHE C 3 105 ? 13.450 44.949 -21.765 1.00 18.76 ? 103 PHE C CD2 1 ATOM 3719 C CE1 . PHE C 3 105 ? 15.643 44.741 -20.085 1.00 19.36 ? 103 PHE C CE1 1 ATOM 3720 C CE2 . PHE C 3 105 ? 13.266 44.755 -20.389 1.00 18.74 ? 103 PHE C CE2 1 ATOM 3721 C CZ . PHE C 3 105 ? 14.356 44.640 -19.550 1.00 18.58 ? 103 PHE C CZ 1 ATOM 3722 N N . GLY C 3 106 ? 13.601 43.992 -26.525 1.00 20.85 ? 104 GLY C N 1 ATOM 3723 C CA . GLY C 3 106 ? 13.152 44.502 -27.808 1.00 22.09 ? 104 GLY C CA 1 ATOM 3724 C C . GLY C 3 106 ? 12.710 45.935 -27.637 1.00 22.36 ? 104 GLY C C 1 ATOM 3725 O O . GLY C 3 106 ? 12.497 46.384 -26.515 1.00 22.63 ? 104 GLY C O 1 ATOM 3726 N N . ALA C 3 107 ? 12.584 46.660 -28.747 1.00 23.12 ? 105 ALA C N 1 ATOM 3727 C CA . ALA C 3 107 ? 12.086 48.034 -28.714 1.00 23.05 ? 105 ALA C CA 1 ATOM 3728 C C . ALA C 3 107 ? 10.548 48.100 -28.545 1.00 24.02 ? 105 ALA C C 1 ATOM 3729 O O . ALA C 3 107 ? 9.983 49.167 -28.304 1.00 25.89 ? 105 ALA C O 1 ATOM 3730 C CB . ALA C 3 107 ? 12.537 48.790 -29.940 1.00 21.71 ? 105 ALA C CB 1 ATOM 3731 N N . GLY C 3 108 ? 9.872 46.965 -28.653 1.00 23.51 ? 106 GLY C N 1 ATOM 3732 C CA . GLY C 3 108 ? 8.426 46.946 -28.484 1.00 23.08 ? 106 GLY C CA 1 ATOM 3733 C C . GLY C 3 108 ? 7.631 47.001 -29.772 1.00 22.80 ? 106 GLY C C 1 ATOM 3734 O O . GLY C 3 108 ? 8.141 47.384 -30.823 1.00 22.46 ? 106 GLY C O 1 ATOM 3735 N N . THR C 3 109 ? 6.379 46.584 -29.683 1.00 22.74 ? 107 THR C N 1 ATOM 3736 C CA . THR C 3 109 ? 5.428 46.706 -30.777 1.00 24.22 ? 107 THR C CA 1 ATOM 3737 C C . THR C 3 109 ? 4.304 47.584 -30.256 1.00 24.82 ? 107 THR C C 1 ATOM 3738 O O . THR C 3 109 ? 3.731 47.299 -29.206 1.00 24.88 ? 107 THR C O 1 ATOM 3739 C CB . THR C 3 109 ? 4.826 45.325 -31.158 1.00 24.52 ? 107 THR C CB 1 ATOM 3740 O OG1 . THR C 3 109 ? 5.792 44.532 -31.862 1.00 24.73 ? 107 THR C OG1 1 ATOM 3741 C CG2 . THR C 3 109 ? 3.604 45.498 -32.025 1.00 24.38 ? 107 THR C CG2 1 ATOM 3742 N N . GLN C 3 110 ? 3.982 48.657 -30.961 1.00 26.77 ? 108 GLN C N 1 ATOM 3743 C CA . GLN C 3 110 ? 2.882 49.510 -30.507 1.00 29.03 ? 108 GLN C CA 1 ATOM 3744 C C . GLN C 3 110 ? 1.519 49.068 -31.068 1.00 27.17 ? 108 GLN C C 1 ATOM 3745 O O . GLN C 3 110 ? 1.334 48.947 -32.276 1.00 26.69 ? 108 GLN C O 1 ATOM 3746 C CB . GLN C 3 110 ? 3.170 50.969 -30.828 1.00 34.06 ? 108 GLN C CB 1 ATOM 3747 C CG . GLN C 3 110 ? 2.022 51.917 -30.500 1.00 40.55 ? 108 GLN C CG 1 ATOM 3748 C CD . GLN C 3 110 ? 2.264 53.307 -31.062 1.00 46.08 ? 108 GLN C CD 1 ATOM 3749 O OE1 . GLN C 3 110 ? 3.310 53.920 -30.796 1.00 49.42 ? 108 GLN C OE1 1 ATOM 3750 N NE2 . GLN C 3 110 ? 1.307 53.808 -31.854 1.00 45.30 ? 108 GLN C NE2 1 ATOM 3751 N N . LEU C 3 111 ? 0.582 48.799 -30.175 1.00 25.07 ? 109 LEU C N 1 ATOM 3752 C CA . LEU C 3 111 ? -0.736 48.406 -30.584 1.00 25.31 ? 109 LEU C CA 1 ATOM 3753 C C . LEU C 3 111 ? -1.708 49.529 -30.286 1.00 27.51 ? 109 LEU C C 1 ATOM 3754 O O . LEU C 3 111 ? -1.621 50.176 -29.231 1.00 29.83 ? 109 LEU C O 1 ATOM 3755 C CB . LEU C 3 111 ? -1.163 47.140 -29.848 1.00 24.25 ? 109 LEU C CB 1 ATOM 3756 C CG . LEU C 3 111 ? -2.601 46.634 -30.056 1.00 22.45 ? 109 LEU C CG 1 ATOM 3757 C CD1 . LEU C 3 111 ? -2.804 46.163 -31.481 1.00 21.57 ? 109 LEU C CD1 1 ATOM 3758 C CD2 . LEU C 3 111 ? -2.929 45.521 -29.080 1.00 21.45 ? 109 LEU C CD2 1 ATOM 3759 N N . ILE C 3 112 ? -2.613 49.778 -31.230 1.00 28.21 ? 110 ILE C N 1 ATOM 3760 C CA . ILE C 3 112 ? -3.760 50.643 -30.979 1.00 29.24 ? 110 ILE C CA 1 ATOM 3761 C C . ILE C 3 112 ? -5.044 49.888 -31.320 1.00 29.39 ? 110 ILE C C 1 ATOM 3762 O O . ILE C 3 112 ? -5.205 49.370 -32.428 1.00 29.34 ? 110 ILE C O 1 ATOM 3763 C CB . ILE C 3 112 ? -3.688 51.983 -31.753 1.00 29.32 ? 110 ILE C CB 1 ATOM 3764 C CG1 . ILE C 3 112 ? -2.522 52.838 -31.243 1.00 29.80 ? 110 ILE C CG1 1 ATOM 3765 C CG2 . ILE C 3 112 ? -5.000 52.743 -31.597 1.00 28.31 ? 110 ILE C CG2 1 ATOM 3766 C CD1 . ILE C 3 112 ? -2.149 54.032 -32.151 1.00 30.51 ? 110 ILE C CD1 1 ATOM 3767 N N . VAL C 3 113 ? -5.940 49.814 -30.345 1.00 29.28 ? 111 VAL C N 1 ATOM 3768 C CA . VAL C 3 113 ? -7.235 49.173 -30.530 1.00 29.07 ? 111 VAL C CA 1 ATOM 3769 C C . VAL C 3 113 ? -8.286 50.253 -30.710 1.00 30.23 ? 111 VAL C C 1 ATOM 3770 O O . VAL C 3 113 ? -8.476 51.086 -29.824 1.00 30.76 ? 111 VAL C O 1 ATOM 3771 C CB . VAL C 3 113 ? -7.623 48.324 -29.312 1.00 27.89 ? 111 VAL C CB 1 ATOM 3772 C CG1 . VAL C 3 113 ? -8.996 47.726 -29.510 1.00 26.76 ? 111 VAL C CG1 1 ATOM 3773 C CG2 . VAL C 3 113 ? -6.570 47.239 -29.040 1.00 26.61 ? 111 VAL C CG2 1 ATOM 3774 N N . ILE C 3 114 ? -8.966 50.246 -31.856 1.00 31.62 ? 112 ILE C N 1 ATOM 3775 C CA . ILE C 3 114 ? -10.039 51.214 -32.105 1.00 30.77 ? 112 ILE C CA 1 ATOM 3776 C C . ILE C 3 114 ? -11.325 50.708 -31.483 1.00 30.95 ? 112 ILE C C 1 ATOM 3777 O O . ILE C 3 114 ? -11.756 49.604 -31.800 1.00 31.26 ? 112 ILE C O 1 ATOM 3778 C CB . ILE C 3 114 ? -10.206 51.513 -33.589 1.00 29.11 ? 112 ILE C CB 1 ATOM 3779 C CG1 . ILE C 3 114 ? -9.001 52.340 -34.050 1.00 29.66 ? 112 ILE C CG1 1 ATOM 3780 C CG2 . ILE C 3 114 ? -11.521 52.233 -33.834 1.00 28.11 ? 112 ILE C CG2 1 ATOM 3781 C CD1 . ILE C 3 114 ? -8.984 52.696 -35.522 1.00 31.56 ? 112 ILE C CD1 1 ATOM 3782 N N . PRO C 3 115 ? -11.921 51.505 -30.578 1.00 32.86 ? 113 PRO C N 1 ATOM 3783 C CA . PRO C 3 115 ? -13.112 51.097 -29.818 1.00 35.82 ? 113 PRO C CA 1 ATOM 3784 C C . PRO C 3 115 ? -14.405 51.068 -30.632 1.00 37.44 ? 113 PRO C C 1 ATOM 3785 O O . PRO C 3 115 ? -14.618 51.876 -31.550 1.00 34.49 ? 113 PRO C O 1 ATOM 3786 C CB . PRO C 3 115 ? -13.220 52.166 -28.724 1.00 35.85 ? 113 PRO C CB 1 ATOM 3787 C CG . PRO C 3 115 ? -12.595 53.389 -29.328 1.00 35.05 ? 113 PRO C CG 1 ATOM 3788 C CD . PRO C 3 115 ? -11.497 52.881 -30.244 1.00 34.27 ? 113 PRO C CD 1 ATOM 3789 N N . ASP C 3 116 ? -15.264 50.135 -30.259 1.00 40.97 ? 114 ASP C N 1 ATOM 3790 C CA . ASP C 3 116 ? -16.548 49.955 -30.903 1.00 45.50 ? 114 ASP C CA 1 ATOM 3791 C C . ASP C 3 116 ? -17.636 50.826 -30.264 1.00 45.68 ? 114 ASP C C 1 ATOM 3792 O O . ASP C 3 116 ? -18.096 50.543 -29.161 1.00 46.27 ? 114 ASP C O 1 ATOM 3793 C CB . ASP C 3 116 ? -16.938 48.477 -30.829 1.00 48.93 ? 114 ASP C CB 1 ATOM 3794 C CG . ASP C 3 116 ? -17.932 48.079 -31.894 1.00 53.08 ? 114 ASP C CG 1 ATOM 3795 O OD1 . ASP C 3 116 ? -18.276 48.920 -32.764 1.00 54.87 ? 114 ASP C OD1 1 ATOM 3796 O OD2 . ASP C 3 116 ? -18.362 46.907 -31.861 1.00 56.56 ? 114 ASP C OD2 1 ATOM 3797 N N . ILE C 3 117 ? -18.044 51.883 -30.961 1.00 48.68 ? 115 ILE C N 1 ATOM 3798 C CA . ILE C 3 117 ? -19.151 52.732 -30.507 1.00 50.03 ? 115 ILE C CA 1 ATOM 3799 C C . ILE C 3 117 ? -20.498 52.145 -30.930 1.00 52.17 ? 115 ILE C C 1 ATOM 3800 O O . ILE C 3 117 ? -20.870 52.182 -32.104 1.00 48.18 ? 115 ILE C O 1 ATOM 3801 C CB . ILE C 3 117 ? -19.018 54.190 -31.007 1.00 49.50 ? 115 ILE C CB 1 ATOM 3802 C CG1 . ILE C 3 117 ? -17.674 54.798 -30.577 1.00 47.33 ? 115 ILE C CG1 1 ATOM 3803 C CG2 . ILE C 3 117 ? -20.201 55.033 -30.521 1.00 51.29 ? 115 ILE C CG2 1 ATOM 3804 C CD1 . ILE C 3 117 ? -17.381 54.693 -29.090 1.00 46.04 ? 115 ILE C CD1 1 ATOM 3805 N N . GLN C 3 118 ? -21.217 51.604 -29.952 1.00 59.93 ? 116 GLN C N 1 ATOM 3806 C CA . GLN C 3 118 ? -22.488 50.918 -30.192 1.00 67.19 ? 116 GLN C CA 1 ATOM 3807 C C . GLN C 3 118 ? -23.572 51.873 -30.714 1.00 68.16 ? 116 GLN C C 1 ATOM 3808 O O . GLN C 3 118 ? -24.179 51.630 -31.761 1.00 66.22 ? 116 GLN C O 1 ATOM 3809 C CB . GLN C 3 118 ? -22.959 50.200 -28.913 1.00 69.90 ? 116 GLN C CB 1 ATOM 3810 C CG . GLN C 3 118 ? -22.033 49.064 -28.413 1.00 74.19 ? 116 GLN C CG 1 ATOM 3811 C CD . GLN C 3 118 ? -22.286 47.712 -29.098 1.00 75.62 ? 116 GLN C CD 1 ATOM 3812 O OE1 . GLN C 3 118 ? -22.777 46.771 -28.470 1.00 73.82 ? 116 GLN C OE1 1 ATOM 3813 N NE2 . GLN C 3 118 ? -21.952 47.616 -30.385 1.00 73.49 ? 116 GLN C NE2 1 ATOM 3814 N N . ASN C 3 119 ? -23.783 52.973 -29.994 1.00 68.55 ? 117 ASN C N 1 ATOM 3815 C CA . ASN C 3 119 ? -24.896 53.870 -30.277 1.00 66.12 ? 117 ASN C CA 1 ATOM 3816 C C . ASN C 3 119 ? -24.507 55.348 -30.383 1.00 63.06 ? 117 ASN C C 1 ATOM 3817 O O . ASN C 3 119 ? -24.670 56.112 -29.424 1.00 62.36 ? 117 ASN C O 1 ATOM 3818 C CB . ASN C 3 119 ? -26.002 53.639 -29.247 1.00 66.37 ? 117 ASN C CB 1 ATOM 3819 C CG . ASN C 3 119 ? -26.516 52.212 -29.277 1.00 67.36 ? 117 ASN C CG 1 ATOM 3820 O OD1 . ASN C 3 119 ? -26.159 51.394 -28.428 1.00 67.80 ? 117 ASN C OD1 1 ATOM 3821 N ND2 . ASN C 3 119 ? -27.324 51.895 -30.285 1.00 65.48 ? 117 ASN C ND2 1 ATOM 3822 N N . PRO C 3 120 ? -24.004 55.755 -31.565 1.00 59.35 ? 118 PRO C N 1 ATOM 3823 C CA . PRO C 3 120 ? -23.575 57.138 -31.801 1.00 57.89 ? 118 PRO C CA 1 ATOM 3824 C C . PRO C 3 120 ? -24.715 58.150 -31.619 1.00 56.78 ? 118 PRO C C 1 ATOM 3825 O O . PRO C 3 120 ? -25.883 57.805 -31.769 1.00 58.09 ? 118 PRO C O 1 ATOM 3826 C CB . PRO C 3 120 ? -23.089 57.117 -33.257 1.00 56.63 ? 118 PRO C CB 1 ATOM 3827 C CG . PRO C 3 120 ? -23.764 55.937 -33.868 1.00 58.11 ? 118 PRO C CG 1 ATOM 3828 C CD . PRO C 3 120 ? -23.871 54.923 -32.776 1.00 58.21 ? 118 PRO C CD 1 ATOM 3829 N N . ASP C 3 121 ? -24.353 59.387 -31.290 1.00 54.13 ? 119 ASP C N 1 ATOM 3830 C CA . ASP C 3 121 ? -25.298 60.449 -30.982 1.00 50.58 ? 119 ASP C CA 1 ATOM 3831 C C . ASP C 3 121 ? -24.563 61.802 -31.029 1.00 51.02 ? 119 ASP C C 1 ATOM 3832 O O . ASP C 3 121 ? -24.705 62.613 -30.110 1.00 53.82 ? 119 ASP C O 1 ATOM 3833 C CB . ASP C 3 121 ? -25.881 60.204 -29.582 1.00 50.50 ? 119 ASP C CB 1 ATOM 3834 C CG . ASP C 3 121 ? -27.153 61.000 -29.310 1.00 52.66 ? 119 ASP C CG 1 ATOM 3835 O OD1 . ASP C 3 121 ? -27.589 61.786 -30.183 1.00 55.77 ? 119 ASP C OD1 1 ATOM 3836 O OD2 . ASP C 3 121 ? -27.722 60.833 -28.208 1.00 49.36 ? 119 ASP C OD2 1 ATOM 3837 N N . PRO C 3 122 ? -23.778 62.059 -32.102 1.00 48.91 ? 120 PRO C N 1 ATOM 3838 C CA . PRO C 3 122 ? -22.904 63.237 -32.147 1.00 48.22 ? 120 PRO C CA 1 ATOM 3839 C C . PRO C 3 122 ? -23.612 64.537 -31.782 1.00 47.64 ? 120 PRO C C 1 ATOM 3840 O O . PRO C 3 122 ? -24.629 64.898 -32.385 1.00 49.13 ? 120 PRO C O 1 ATOM 3841 C CB . PRO C 3 122 ? -22.443 63.289 -33.612 1.00 49.13 ? 120 PRO C CB 1 ATOM 3842 C CG . PRO C 3 122 ? -23.440 62.490 -34.356 1.00 50.35 ? 120 PRO C CG 1 ATOM 3843 C CD . PRO C 3 122 ? -23.818 61.386 -33.410 1.00 50.08 ? 120 PRO C CD 1 ATOM 3844 N N . ALA C 3 123 ? -23.071 65.219 -30.782 1.00 45.06 ? 121 ALA C N 1 ATOM 3845 C CA . ALA C 3 123 ? -23.616 66.480 -30.308 1.00 42.01 ? 121 ALA C CA 1 ATOM 3846 C C . ALA C 3 123 ? -22.455 67.409 -30.046 1.00 41.35 ? 121 ALA C C 1 ATOM 3847 O O . ALA C 3 123 ? -21.299 66.964 -30.003 1.00 40.71 ? 121 ALA C O 1 ATOM 3848 C CB . ALA C 3 123 ? -24.428 66.268 -29.049 1.00 38.86 ? 121 ALA C CB 1 ATOM 3849 N N . VAL C 3 124 ? -22.766 68.700 -29.916 1.00 41.23 ? 122 VAL C N 1 ATOM 3850 C CA . VAL C 3 124 ? -21.803 69.716 -29.479 1.00 39.87 ? 122 VAL C CA 1 ATOM 3851 C C . VAL C 3 124 ? -22.426 70.584 -28.394 1.00 40.81 ? 122 VAL C C 1 ATOM 3852 O O . VAL C 3 124 ? -23.401 71.297 -28.640 1.00 42.17 ? 122 VAL C O 1 ATOM 3853 C CB . VAL C 3 124 ? -21.343 70.607 -30.622 1.00 39.56 ? 122 VAL C CB 1 ATOM 3854 C CG1 . VAL C 3 124 ? -20.421 71.691 -30.094 1.00 40.12 ? 122 VAL C CG1 1 ATOM 3855 C CG2 . VAL C 3 124 ? -20.646 69.783 -31.686 1.00 40.35 ? 122 VAL C CG2 1 ATOM 3856 N N . TYR C 3 125 ? -21.860 70.511 -27.190 1.00 42.53 ? 123 TYR C N 1 ATOM 3857 C CA . TYR C 3 125 ? -22.409 71.209 -26.027 1.00 39.96 ? 123 TYR C CA 1 ATOM 3858 C C . TYR C 3 125 ? -21.518 72.338 -25.584 1.00 39.85 ? 123 TYR C C 1 ATOM 3859 O O . TYR C 3 125 ? -20.331 72.382 -25.935 1.00 40.62 ? 123 TYR C O 1 ATOM 3860 C CB . TYR C 3 125 ? -22.612 70.245 -24.866 1.00 39.69 ? 123 TYR C CB 1 ATOM 3861 C CG . TYR C 3 125 ? -23.490 69.061 -25.192 1.00 40.31 ? 123 TYR C CG 1 ATOM 3862 C CD1 . TYR C 3 125 ? -24.861 69.216 -25.389 1.00 40.40 ? 123 TYR C CD1 1 ATOM 3863 C CD2 . TYR C 3 125 ? -22.950 67.779 -25.286 1.00 40.45 ? 123 TYR C CD2 1 ATOM 3864 C CE1 . TYR C 3 125 ? -25.679 68.114 -25.683 1.00 42.55 ? 123 TYR C CE1 1 ATOM 3865 C CE2 . TYR C 3 125 ? -23.752 66.674 -25.577 1.00 41.34 ? 123 TYR C CE2 1 ATOM 3866 C CZ . TYR C 3 125 ? -25.114 66.846 -25.776 1.00 41.14 ? 123 TYR C CZ 1 ATOM 3867 O OH . TYR C 3 125 ? -25.903 65.759 -26.063 1.00 38.54 ? 123 TYR C OH 1 ATOM 3868 N N . GLN C 3 126 ? -22.099 73.256 -24.815 1.00 41.37 ? 124 GLN C N 1 ATOM 3869 C CA . GLN C 3 126 ? -21.342 74.333 -24.196 1.00 43.23 ? 124 GLN C CA 1 ATOM 3870 C C . GLN C 3 126 ? -21.275 74.131 -22.677 1.00 42.41 ? 124 GLN C C 1 ATOM 3871 O O . GLN C 3 126 ? -22.294 73.955 -22.007 1.00 42.80 ? 124 GLN C O 1 ATOM 3872 C CB . GLN C 3 126 ? -21.926 75.696 -24.570 1.00 44.77 ? 124 GLN C CB 1 ATOM 3873 C CG . GLN C 3 126 ? -21.133 76.868 -24.011 1.00 51.27 ? 124 GLN C CG 1 ATOM 3874 C CD . GLN C 3 126 ? -21.259 78.141 -24.836 1.00 56.27 ? 124 GLN C CD 1 ATOM 3875 O OE1 . GLN C 3 126 ? -21.593 79.204 -24.303 1.00 57.51 ? 124 GLN C OE1 1 ATOM 3876 N NE2 . GLN C 3 126 ? -20.979 78.045 -26.140 1.00 60.82 ? 124 GLN C NE2 1 ATOM 3877 N N . LEU C 3 127 ? -20.060 74.131 -22.145 1.00 43.57 ? 125 LEU C N 1 ATOM 3878 C CA . LEU C 3 127 ? -19.842 73.928 -20.708 1.00 44.24 ? 125 LEU C CA 1 ATOM 3879 C C . LEU C 3 127 ? -19.288 75.198 -20.055 1.00 43.95 ? 125 LEU C C 1 ATOM 3880 O O . LEU C 3 127 ? -18.354 75.805 -20.570 1.00 44.97 ? 125 LEU C O 1 ATOM 3881 C CB . LEU C 3 127 ? -18.908 72.732 -20.470 1.00 41.30 ? 125 LEU C CB 1 ATOM 3882 C CG . LEU C 3 127 ? -19.388 71.304 -20.793 1.00 39.47 ? 125 LEU C CG 1 ATOM 3883 C CD1 . LEU C 3 127 ? -19.866 71.093 -22.225 1.00 36.75 ? 125 LEU C CD1 1 ATOM 3884 C CD2 . LEU C 3 127 ? -18.263 70.346 -20.505 1.00 38.67 ? 125 LEU C CD2 1 ATOM 3885 N N . ARG C 3 128 ? -19.871 75.592 -18.928 1.00 46.07 ? 126 ARG C N 1 ATOM 3886 C CA . ARG C 3 128 ? -19.491 76.832 -18.248 1.00 49.56 ? 126 ARG C CA 1 ATOM 3887 C C . ARG C 3 128 ? -18.432 76.597 -17.172 1.00 48.09 ? 126 ARG C C 1 ATOM 3888 O O . ARG C 3 128 ? -18.442 75.574 -16.496 1.00 44.24 ? 126 ARG C O 1 ATOM 3889 C CB . ARG C 3 128 ? -20.725 77.493 -17.615 1.00 56.37 ? 126 ARG C CB 1 ATOM 3890 C CG . ARG C 3 128 ? -21.789 77.990 -18.602 1.00 62.72 ? 126 ARG C CG 1 ATOM 3891 C CD . ARG C 3 128 ? -21.429 79.357 -19.146 1.00 69.90 ? 126 ARG C CD 1 ATOM 3892 N NE . ARG C 3 128 ? -22.242 79.739 -20.299 1.00 74.98 ? 126 ARG C NE 1 ATOM 3893 C CZ . ARG C 3 128 ? -21.937 80.740 -21.124 1.00 78.09 ? 126 ARG C CZ 1 ATOM 3894 N NH1 . ARG C 3 128 ? -20.833 81.454 -20.931 1.00 79.46 ? 126 ARG C NH1 1 ATOM 3895 N NH2 . ARG C 3 128 ? -22.728 81.024 -22.150 1.00 79.29 ? 126 ARG C NH2 1 ATOM 3896 N N . ASP C 3 129 ? -17.525 77.555 -17.013 1.00 50.99 ? 127 ASP C N 1 ATOM 3897 C CA . ASP C 3 129 ? -16.533 77.510 -15.932 1.00 52.71 ? 127 ASP C CA 1 ATOM 3898 C C . ASP C 3 129 ? -17.202 77.732 -14.571 1.00 51.25 ? 127 ASP C C 1 ATOM 3899 O O . ASP C 3 129 ? -18.065 78.605 -14.429 1.00 50.48 ? 127 ASP C O 1 ATOM 3900 C CB . ASP C 3 129 ? -15.413 78.539 -16.181 1.00 55.99 ? 127 ASP C CB 1 ATOM 3901 C CG . ASP C 3 129 ? -14.423 78.647 -15.018 1.00 59.20 ? 127 ASP C CG 1 ATOM 3902 O OD1 . ASP C 3 129 ? -14.215 77.659 -14.280 1.00 64.31 ? 127 ASP C OD1 1 ATOM 3903 O OD2 . ASP C 3 129 ? -13.838 79.732 -14.845 1.00 59.64 ? 127 ASP C OD2 1 ATOM 3904 N N . SER C 3 130 ? -16.795 76.937 -13.582 1.00 50.67 ? 128 SER C N 1 ATOM 3905 C CA . SER C 3 130 ? -17.373 76.999 -12.238 1.00 53.31 ? 128 SER C CA 1 ATOM 3906 C C . SER C 3 130 ? -17.103 78.329 -11.525 1.00 56.65 ? 128 SER C C 1 ATOM 3907 O O . SER C 3 130 ? -18.002 78.900 -10.907 1.00 57.70 ? 128 SER C O 1 ATOM 3908 C CB . SER C 3 130 ? -16.871 75.837 -11.381 1.00 50.97 ? 128 SER C CB 1 ATOM 3909 O OG . SER C 3 130 ? -15.465 75.893 -11.214 1.00 49.74 ? 128 SER C OG 1 ATOM 3910 N N . LYS C 3 131 ? -15.871 78.820 -11.622 1.00 56.96 ? 129 LYS C N 1 ATOM 3911 C CA . LYS C 3 131 ? -15.488 80.041 -10.933 1.00 59.44 ? 129 LYS C CA 1 ATOM 3912 C C . LYS C 3 131 ? -16.036 81.306 -11.618 1.00 63.53 ? 129 LYS C C 1 ATOM 3913 O O . LYS C 3 131 ? -16.193 82.337 -10.963 1.00 67.76 ? 129 LYS C O 1 ATOM 3914 C CB . LYS C 3 131 ? -13.963 80.108 -10.743 1.00 53.63 ? 129 LYS C CB 1 ATOM 3915 N N . SER C 3 132 ? -16.338 81.229 -12.916 1.00 66.20 ? 130 SER C N 1 ATOM 3916 C CA . SER C 3 132 ? -16.816 82.400 -13.681 1.00 71.59 ? 130 SER C CA 1 ATOM 3917 C C . SER C 3 132 ? -17.667 82.015 -14.900 1.00 76.18 ? 130 SER C C 1 ATOM 3918 O O . SER C 3 132 ? -17.223 81.242 -15.752 1.00 78.80 ? 130 SER C O 1 ATOM 3919 C CB . SER C 3 132 ? -15.636 83.278 -14.124 1.00 67.81 ? 130 SER C CB 1 ATOM 3920 O OG . SER C 3 132 ? -14.920 82.679 -15.191 1.00 61.22 ? 130 SER C OG 1 ATOM 3921 N N . SER C 3 133 ? -18.875 82.571 -14.993 1.00 77.85 ? 131 SER C N 1 ATOM 3922 C CA . SER C 3 133 ? -19.811 82.187 -16.057 1.00 82.05 ? 131 SER C CA 1 ATOM 3923 C C . SER C 3 133 ? -19.475 82.769 -17.446 1.00 80.93 ? 131 SER C C 1 ATOM 3924 O O . SER C 3 133 ? -20.113 82.425 -18.443 1.00 78.54 ? 131 SER C O 1 ATOM 3925 C CB . SER C 3 133 ? -21.263 82.495 -15.651 1.00 86.42 ? 131 SER C CB 1 ATOM 3926 O OG . SER C 3 133 ? -21.521 83.887 -15.623 1.00 88.04 ? 131 SER C OG 1 ATOM 3927 N N . ASP C 3 134 ? -18.466 83.634 -17.501 1.00 80.13 ? 132 ASP C N 1 ATOM 3928 C CA . ASP C 3 134 ? -18.027 84.258 -18.756 1.00 80.83 ? 132 ASP C CA 1 ATOM 3929 C C . ASP C 3 134 ? -17.164 83.351 -19.663 1.00 77.69 ? 132 ASP C C 1 ATOM 3930 O O . ASP C 3 134 ? -17.362 83.329 -20.881 1.00 77.88 ? 132 ASP C O 1 ATOM 3931 C CB . ASP C 3 134 ? -17.327 85.600 -18.482 1.00 87.97 ? 132 ASP C CB 1 ATOM 3932 C CG . ASP C 3 134 ? -16.454 85.569 -17.227 1.00 95.50 ? 132 ASP C CG 1 ATOM 3933 O OD1 . ASP C 3 134 ? -15.357 84.960 -17.266 1.00 96.38 ? 132 ASP C OD1 1 ATOM 3934 O OD2 . ASP C 3 134 ? -16.865 86.167 -16.204 1.00 96.17 ? 132 ASP C OD2 1 ATOM 3935 N N . LYS C 3 135 ? -16.213 82.618 -19.079 1.00 70.74 ? 133 LYS C N 1 ATOM 3936 C CA . LYS C 3 135 ? -15.378 81.683 -19.847 1.00 62.06 ? 133 LYS C CA 1 ATOM 3937 C C . LYS C 3 135 ? -16.112 80.356 -20.039 1.00 56.56 ? 133 LYS C C 1 ATOM 3938 O O . LYS C 3 135 ? -16.945 79.976 -19.210 1.00 56.14 ? 133 LYS C O 1 ATOM 3939 C CB . LYS C 3 135 ? -14.006 81.473 -19.182 1.00 64.02 ? 133 LYS C CB 1 ATOM 3940 C CG . LYS C 3 135 ? -13.189 82.763 -18.998 1.00 65.30 ? 133 LYS C CG 1 ATOM 3941 C CD . LYS C 3 135 ? -11.728 82.497 -18.632 1.00 67.63 ? 133 LYS C CD 1 ATOM 3942 C CE . LYS C 3 135 ? -10.985 83.816 -18.386 1.00 68.11 ? 133 LYS C CE 1 ATOM 3943 N NZ . LYS C 3 135 ? -9.534 83.773 -18.767 1.00 64.90 ? 133 LYS C NZ 1 ATOM 3944 N N . SER C 3 136 ? -15.814 79.663 -21.139 1.00 50.79 ? 134 SER C N 1 ATOM 3945 C CA . SER C 3 136 ? -16.512 78.417 -21.487 1.00 46.49 ? 134 SER C CA 1 ATOM 3946 C C . SER C 3 136 ? -15.758 77.539 -22.490 1.00 43.27 ? 134 SER C C 1 ATOM 3947 O O . SER C 3 136 ? -14.915 78.025 -23.247 1.00 43.40 ? 134 SER C O 1 ATOM 3948 C CB . SER C 3 136 ? -17.907 78.721 -22.041 1.00 48.03 ? 134 SER C CB 1 ATOM 3949 O OG . SER C 3 136 ? -17.844 79.118 -23.403 1.00 47.93 ? 134 SER C OG 1 ATOM 3950 N N . VAL C 3 137 ? -16.075 76.247 -22.493 1.00 40.07 ? 135 VAL C N 1 ATOM 3951 C CA . VAL C 3 137 ? -15.530 75.335 -23.496 1.00 40.03 ? 135 VAL C CA 1 ATOM 3952 C C . VAL C 3 137 ? -16.623 74.729 -24.349 1.00 41.43 ? 135 VAL C C 1 ATOM 3953 O O . VAL C 3 137 ? -17.805 74.686 -23.974 1.00 41.43 ? 135 VAL C O 1 ATOM 3954 C CB . VAL C 3 137 ? -14.646 74.172 -22.915 1.00 37.60 ? 135 VAL C CB 1 ATOM 3955 C CG1 . VAL C 3 137 ? -13.429 74.710 -22.228 1.00 35.47 ? 135 VAL C CG1 1 ATOM 3956 C CG2 . VAL C 3 137 ? -15.452 73.239 -22.000 1.00 37.64 ? 135 VAL C CG2 1 ATOM 3957 N N . CYS C 3 138 ? -16.192 74.214 -25.487 1.00 43.23 ? 136 CYS C N 1 ATOM 3958 C CA . CYS C 3 138 ? -17.084 73.643 -26.448 1.00 46.12 ? 136 CYS C CA 1 ATOM 3959 C C . CYS C 3 138 ? -16.745 72.153 -26.672 1.00 43.22 ? 136 CYS C C 1 ATOM 3960 O O . CYS C 3 138 ? -15.687 71.816 -27.215 1.00 41.59 ? 136 CYS C O 1 ATOM 3961 C CB . CYS C 3 138 ? -16.978 74.480 -27.714 1.00 54.06 ? 136 CYS C CB 1 ATOM 3962 S SG . CYS C 3 138 ? -18.358 74.309 -28.794 1.00 74.57 ? 136 CYS C SG 1 ATOM 3963 N N . LEU C 3 139 ? -17.649 71.274 -26.227 1.00 40.22 ? 137 LEU C N 1 ATOM 3964 C CA . LEU C 3 139 ? -17.428 69.815 -26.215 1.00 37.73 ? 137 LEU C CA 1 ATOM 3965 C C . LEU C 3 139 ? -18.207 69.061 -27.295 1.00 39.71 ? 137 LEU C C 1 ATOM 3966 O O . LEU C 3 139 ? -19.441 69.014 -27.268 1.00 39.19 ? 137 LEU C O 1 ATOM 3967 C CB . LEU C 3 139 ? -17.781 69.226 -24.839 1.00 34.80 ? 137 LEU C CB 1 ATOM 3968 C CG . LEU C 3 139 ? -18.001 67.710 -24.692 1.00 33.27 ? 137 LEU C CG 1 ATOM 3969 C CD1 . LEU C 3 139 ? -16.694 66.933 -24.625 1.00 32.46 ? 137 LEU C CD1 1 ATOM 3970 C CD2 . LEU C 3 139 ? -18.851 67.383 -23.492 1.00 31.97 ? 137 LEU C CD2 1 ATOM 3971 N N . PHE C 3 140 ? -17.465 68.455 -28.219 1.00 41.15 ? 138 PHE C N 1 ATOM 3972 C CA . PHE C 3 140 ? -18.012 67.622 -29.287 1.00 41.47 ? 138 PHE C CA 1 ATOM 3973 C C . PHE C 3 140 ? -17.910 66.168 -28.841 1.00 41.58 ? 138 PHE C C 1 ATOM 3974 O O . PHE C 3 140 ? -16.808 65.636 -28.728 1.00 42.83 ? 138 PHE C O 1 ATOM 3975 C CB . PHE C 3 140 ? -17.203 67.874 -30.574 1.00 42.28 ? 138 PHE C CB 1 ATOM 3976 C CG . PHE C 3 140 ? -17.594 67.012 -31.749 1.00 43.73 ? 138 PHE C CG 1 ATOM 3977 C CD1 . PHE C 3 140 ? -18.932 66.709 -32.016 1.00 44.85 ? 138 PHE C CD1 1 ATOM 3978 C CD2 . PHE C 3 140 ? -16.616 66.540 -32.619 1.00 43.52 ? 138 PHE C CD2 1 ATOM 3979 C CE1 . PHE C 3 140 ? -19.278 65.925 -33.113 1.00 46.84 ? 138 PHE C CE1 1 ATOM 3980 C CE2 . PHE C 3 140 ? -16.948 65.747 -33.721 1.00 44.53 ? 138 PHE C CE2 1 ATOM 3981 C CZ . PHE C 3 140 ? -18.277 65.436 -33.972 1.00 46.39 ? 138 PHE C CZ 1 ATOM 3982 N N . THR C 3 141 ? -19.047 65.528 -28.582 1.00 42.10 ? 139 THR C N 1 ATOM 3983 C CA . THR C 3 141 ? -19.045 64.161 -28.025 1.00 44.14 ? 139 THR C CA 1 ATOM 3984 C C . THR C 3 141 ? -19.968 63.158 -28.732 1.00 43.81 ? 139 THR C C 1 ATOM 3985 O O . THR C 3 141 ? -20.809 63.526 -29.541 1.00 46.56 ? 139 THR C O 1 ATOM 3986 C CB . THR C 3 141 ? -19.380 64.170 -26.492 1.00 44.97 ? 139 THR C CB 1 ATOM 3987 O OG1 . THR C 3 141 ? -19.238 62.849 -25.940 1.00 44.62 ? 139 THR C OG1 1 ATOM 3988 C CG2 . THR C 3 141 ? -20.802 64.684 -26.243 1.00 43.97 ? 139 THR C CG2 1 ATOM 3989 N N . ASP C 3 142 ? -19.789 61.885 -28.407 1.00 44.51 ? 140 ASP C N 1 ATOM 3990 C CA . ASP C 3 142 ? -20.683 60.806 -28.833 1.00 46.32 ? 140 ASP C CA 1 ATOM 3991 C C . ASP C 3 142 ? -20.701 60.470 -30.328 1.00 45.54 ? 140 ASP C C 1 ATOM 3992 O O . ASP C 3 142 ? -21.616 59.811 -30.807 1.00 46.64 ? 140 ASP C O 1 ATOM 3993 C CB . ASP C 3 142 ? -22.095 61.021 -28.284 1.00 47.72 ? 140 ASP C CB 1 ATOM 3994 C CG . ASP C 3 142 ? -22.160 60.849 -26.786 1.00 51.56 ? 140 ASP C CG 1 ATOM 3995 O OD1 . ASP C 3 142 ? -21.090 60.920 -26.136 1.00 53.24 ? 140 ASP C OD1 1 ATOM 3996 O OD2 . ASP C 3 142 ? -23.273 60.640 -26.253 1.00 53.26 ? 140 ASP C OD2 1 ATOM 3997 N N . PHE C 3 143 ? -19.676 60.900 -31.051 1.00 44.75 ? 141 PHE C N 1 ATOM 3998 C CA . PHE C 3 143 ? -19.484 60.466 -32.427 1.00 45.72 ? 141 PHE C CA 1 ATOM 3999 C C . PHE C 3 143 ? -18.883 59.056 -32.509 1.00 46.72 ? 141 PHE C C 1 ATOM 4000 O O . PHE C 3 143 ? -18.320 58.553 -31.536 1.00 47.42 ? 141 PHE C O 1 ATOM 4001 C CB . PHE C 3 143 ? -18.657 61.487 -33.223 1.00 45.12 ? 141 PHE C CB 1 ATOM 4002 C CG . PHE C 3 143 ? -17.385 61.925 -32.552 1.00 44.23 ? 141 PHE C CG 1 ATOM 4003 C CD1 . PHE C 3 143 ? -16.176 61.332 -32.879 1.00 45.80 ? 141 PHE C CD1 1 ATOM 4004 C CD2 . PHE C 3 143 ? -17.386 62.962 -31.628 1.00 45.30 ? 141 PHE C CD2 1 ATOM 4005 C CE1 . PHE C 3 143 ? -14.987 61.753 -32.279 1.00 45.32 ? 141 PHE C CE1 1 ATOM 4006 C CE2 . PHE C 3 143 ? -16.204 63.389 -31.020 1.00 43.59 ? 141 PHE C CE2 1 ATOM 4007 C CZ . PHE C 3 143 ? -15.006 62.786 -31.349 1.00 43.67 ? 141 PHE C CZ 1 ATOM 4008 N N . ASP C 3 144 ? -19.031 58.403 -33.656 1.00 48.38 ? 142 ASP C N 1 ATOM 4009 C CA . ASP C 3 144 ? -18.403 57.099 -33.823 1.00 52.82 ? 142 ASP C CA 1 ATOM 4010 C C . ASP C 3 144 ? -16.949 57.256 -34.260 1.00 52.82 ? 142 ASP C C 1 ATOM 4011 O O . ASP C 3 144 ? -16.508 58.354 -34.588 1.00 49.00 ? 142 ASP C O 1 ATOM 4012 C CB . ASP C 3 144 ? -19.220 56.141 -34.729 1.00 54.66 ? 142 ASP C CB 1 ATOM 4013 C CG . ASP C 3 144 ? -19.100 56.450 -36.229 1.00 54.72 ? 142 ASP C CG 1 ATOM 4014 O OD1 . ASP C 3 144 ? -18.589 57.526 -36.627 1.00 55.40 ? 142 ASP C OD1 1 ATOM 4015 O OD2 . ASP C 3 144 ? -19.544 55.589 -37.019 1.00 52.51 ? 142 ASP C OD2 1 ATOM 4016 N N . SER C 3 145 ? -16.218 56.149 -34.247 1.00 57.53 ? 143 SER C N 1 ATOM 4017 C CA . SER C 3 145 ? -14.791 56.147 -34.533 1.00 63.41 ? 143 SER C CA 1 ATOM 4018 C C . SER C 3 145 ? -14.480 56.324 -36.026 1.00 65.38 ? 143 SER C C 1 ATOM 4019 O O . SER C 3 145 ? -13.319 56.303 -36.438 1.00 66.23 ? 143 SER C O 1 ATOM 4020 C CB . SER C 3 145 ? -14.156 54.874 -33.967 1.00 66.65 ? 143 SER C CB 1 ATOM 4021 O OG . SER C 3 145 ? -15.096 53.808 -33.938 1.00 72.74 ? 143 SER C OG 1 ATOM 4022 N N . GLN C 3 146 ? -15.526 56.504 -36.827 1.00 68.39 ? 144 GLN C N 1 ATOM 4023 C CA . GLN C 3 146 ? -15.370 56.846 -38.237 1.00 70.38 ? 144 GLN C CA 1 ATOM 4024 C C . GLN C 3 146 ? -15.038 58.341 -38.405 1.00 68.69 ? 144 GLN C C 1 ATOM 4025 O O . GLN C 3 146 ? -14.364 58.724 -39.360 1.00 70.02 ? 144 GLN C O 1 ATOM 4026 C CB . GLN C 3 146 ? -16.625 56.459 -39.037 1.00 69.43 ? 144 GLN C CB 1 ATOM 4027 N N . THR C 3 147 ? -15.496 59.174 -37.471 1.00 62.95 ? 145 THR C N 1 ATOM 4028 C CA . THR C 3 147 ? -15.262 60.614 -37.539 1.00 61.88 ? 145 THR C CA 1 ATOM 4029 C C . THR C 3 147 ? -13.831 60.985 -37.126 1.00 62.19 ? 145 THR C C 1 ATOM 4030 O O . THR C 3 147 ? -13.308 60.465 -36.138 1.00 62.50 ? 145 THR C O 1 ATOM 4031 C CB . THR C 3 147 ? -16.289 61.393 -36.673 1.00 61.04 ? 145 THR C CB 1 ATOM 4032 O OG1 . THR C 3 147 ? -17.615 60.949 -36.980 1.00 63.06 ? 145 THR C OG1 1 ATOM 4033 C CG2 . THR C 3 147 ? -16.208 62.890 -36.935 1.00 61.19 ? 145 THR C CG2 1 ATOM 4034 N N . ASN C 3 148 ? -13.207 61.870 -37.905 1.00 63.76 ? 146 ASN C N 1 ATOM 4035 C CA . ASN C 3 148 ? -11.896 62.454 -37.584 1.00 65.41 ? 146 ASN C CA 1 ATOM 4036 C C . ASN C 3 148 ? -12.060 63.878 -37.078 1.00 64.11 ? 146 ASN C C 1 ATOM 4037 O O . ASN C 3 148 ? -12.882 64.638 -37.606 1.00 62.93 ? 146 ASN C O 1 ATOM 4038 C CB . ASN C 3 148 ? -10.968 62.491 -38.812 1.00 66.69 ? 146 ASN C CB 1 ATOM 4039 C CG . ASN C 3 148 ? -10.527 61.110 -39.273 1.00 68.91 ? 146 ASN C CG 1 ATOM 4040 O OD1 . ASN C 3 148 ? -9.847 60.378 -38.547 1.00 70.35 ? 146 ASN C OD1 1 ATOM 4041 N ND2 . ASN C 3 148 ? -10.893 60.759 -40.504 1.00 66.52 ? 146 ASN C ND2 1 ATOM 4042 N N . VAL C 3 149 ? -11.267 64.238 -36.070 1.00 61.34 ? 147 VAL C N 1 ATOM 4043 C CA . VAL C 3 149 ? -11.265 65.599 -35.546 1.00 61.18 ? 147 VAL C CA 1 ATOM 4044 C C . VAL C 3 149 ? -10.048 66.355 -36.067 1.00 62.27 ? 147 VAL C C 1 ATOM 4045 O O . VAL C 3 149 ? -8.926 66.178 -35.586 1.00 64.43 ? 147 VAL C O 1 ATOM 4046 C CB . VAL C 3 149 ? -11.312 65.644 -33.997 1.00 60.92 ? 147 VAL C CB 1 ATOM 4047 C CG1 . VAL C 3 149 ? -11.397 67.085 -33.512 1.00 59.59 ? 147 VAL C CG1 1 ATOM 4048 C CG2 . VAL C 3 149 ? -12.491 64.840 -33.464 1.00 59.43 ? 147 VAL C CG2 1 ATOM 4049 N N . SER C 3 150 ? -10.284 67.187 -37.071 1.00 63.84 ? 148 SER C N 1 ATOM 4050 C CA . SER C 3 150 ? -9.236 68.009 -37.644 1.00 66.10 ? 148 SER C CA 1 ATOM 4051 C C . SER C 3 150 ? -9.046 69.262 -36.808 1.00 68.78 ? 148 SER C C 1 ATOM 4052 O O . SER C 3 150 ? -10.016 69.820 -36.282 1.00 67.20 ? 148 SER C O 1 ATOM 4053 C CB . SER C 3 150 ? -9.575 68.375 -39.088 1.00 63.92 ? 148 SER C CB 1 ATOM 4054 O OG . SER C 3 150 ? -9.262 67.306 -39.959 1.00 61.45 ? 148 SER C OG 1 ATOM 4055 N N . GLN C 3 151 ? -7.790 69.695 -36.699 1.00 72.65 ? 149 GLN C N 1 ATOM 4056 C CA . GLN C 3 151 ? -7.410 70.869 -35.908 1.00 77.33 ? 149 GLN C CA 1 ATOM 4057 C C . GLN C 3 151 ? -8.059 72.148 -36.432 1.00 82.27 ? 149 GLN C C 1 ATOM 4058 O O . GLN C 3 151 ? -8.642 72.164 -37.520 1.00 83.57 ? 149 GLN C O 1 ATOM 4059 C CB . GLN C 3 151 ? -5.884 71.018 -35.871 1.00 75.26 ? 149 GLN C CB 1 ATOM 4060 C CG . GLN C 3 151 ? -5.144 69.790 -35.337 1.00 78.22 ? 149 GLN C CG 1 ATOM 4061 C CD . GLN C 3 151 ? -5.434 69.515 -33.867 1.00 80.18 ? 149 GLN C CD 1 ATOM 4062 O OE1 . GLN C 3 151 ? -5.269 70.395 -33.022 1.00 83.57 ? 149 GLN C OE1 1 ATOM 4063 N NE2 . GLN C 3 151 ? -5.861 68.289 -33.556 1.00 76.34 ? 149 GLN C NE2 1 ATOM 4064 N N . SER C 3 152 ? -7.971 73.219 -35.649 1.00 87.71 ? 150 SER C N 1 ATOM 4065 C CA . SER C 3 152 ? -8.586 74.482 -36.039 1.00 92.34 ? 150 SER C CA 1 ATOM 4066 C C . SER C 3 152 ? -7.757 75.217 -37.093 1.00 96.19 ? 150 SER C C 1 ATOM 4067 O O . SER C 3 152 ? -6.538 75.030 -37.185 1.00 95.03 ? 150 SER C O 1 ATOM 4068 C CB . SER C 3 152 ? -8.808 75.378 -34.820 1.00 91.05 ? 150 SER C CB 1 ATOM 4069 O OG . SER C 3 152 ? -9.573 76.517 -35.177 1.00 91.66 ? 150 SER C OG 1 ATOM 4070 N N . LYS C 3 153 ? -8.436 76.044 -37.886 1.00 98.92 ? 151 LYS C N 1 ATOM 4071 C CA . LYS C 3 153 ? -7.785 76.913 -38.866 1.00 96.14 ? 151 LYS C CA 1 ATOM 4072 C C . LYS C 3 153 ? -7.103 78.106 -38.183 1.00 94.67 ? 151 LYS C C 1 ATOM 4073 O O . LYS C 3 153 ? -6.011 78.516 -38.576 1.00 93.27 ? 151 LYS C O 1 ATOM 4074 C CB . LYS C 3 153 ? -8.803 77.400 -39.902 1.00 95.44 ? 151 LYS C CB 1 ATOM 4075 N N . ASP C 3 154 ? -7.756 78.647 -37.156 1.00 91.66 ? 152 ASP C N 1 ATOM 4076 C CA . ASP C 3 154 ? -7.248 79.789 -36.400 1.00 86.97 ? 152 ASP C CA 1 ATOM 4077 C C . ASP C 3 154 ? -6.410 79.345 -35.192 1.00 82.42 ? 152 ASP C C 1 ATOM 4078 O O . ASP C 3 154 ? -6.820 78.464 -34.437 1.00 82.10 ? 152 ASP C O 1 ATOM 4079 C CB . ASP C 3 154 ? -8.428 80.654 -35.941 1.00 87.62 ? 152 ASP C CB 1 ATOM 4080 C CG . ASP C 3 154 ? -8.002 82.019 -35.427 1.00 88.53 ? 152 ASP C CG 1 ATOM 4081 O OD1 . ASP C 3 154 ? -6.789 82.255 -35.239 1.00 85.82 ? 152 ASP C OD1 1 ATOM 4082 O OD2 . ASP C 3 154 ? -8.896 82.862 -35.202 1.00 90.21 ? 152 ASP C OD2 1 ATOM 4083 N N . SER C 3 155 ? -5.246 79.967 -35.011 1.00 78.47 ? 153 SER C N 1 ATOM 4084 C CA . SER C 3 155 ? -4.381 79.672 -33.861 1.00 77.60 ? 153 SER C CA 1 ATOM 4085 C C . SER C 3 155 ? -4.890 80.334 -32.574 1.00 74.94 ? 153 SER C C 1 ATOM 4086 O O . SER C 3 155 ? -4.370 80.080 -31.488 1.00 72.91 ? 153 SER C O 1 ATOM 4087 C CB . SER C 3 155 ? -2.912 80.039 -34.143 1.00 77.85 ? 153 SER C CB 1 ATOM 4088 O OG . SER C 3 155 ? -2.744 81.428 -34.375 1.00 73.48 ? 153 SER C OG 1 ATOM 4089 N N . ASP C 3 156 ? -5.904 81.186 -32.714 1.00 73.45 ? 154 ASP C N 1 ATOM 4090 C CA . ASP C 3 156 ? -6.672 81.698 -31.578 1.00 71.54 ? 154 ASP C CA 1 ATOM 4091 C C . ASP C 3 156 ? -7.469 80.573 -30.921 1.00 66.65 ? 154 ASP C C 1 ATOM 4092 O O . ASP C 3 156 ? -7.651 80.560 -29.701 1.00 67.52 ? 154 ASP C O 1 ATOM 4093 C CB . ASP C 3 156 ? -7.640 82.805 -32.029 1.00 76.68 ? 154 ASP C CB 1 ATOM 4094 C CG . ASP C 3 156 ? -7.207 84.199 -31.582 1.00 81.14 ? 154 ASP C CG 1 ATOM 4095 O OD1 . ASP C 3 156 ? -6.042 84.367 -31.144 1.00 81.11 ? 154 ASP C OD1 1 ATOM 4096 O OD2 . ASP C 3 156 ? -8.048 85.128 -31.665 1.00 79.21 ? 154 ASP C OD2 1 ATOM 4097 N N . VAL C 3 157 ? -7.937 79.639 -31.745 1.00 57.96 ? 155 VAL C N 1 ATOM 4098 C CA . VAL C 3 157 ? -8.769 78.531 -31.302 1.00 53.10 ? 155 VAL C CA 1 ATOM 4099 C C . VAL C 3 157 ? -7.919 77.286 -31.007 1.00 51.30 ? 155 VAL C C 1 ATOM 4100 O O . VAL C 3 157 ? -6.894 77.058 -31.655 1.00 52.80 ? 155 VAL C O 1 ATOM 4101 C CB . VAL C 3 157 ? -9.858 78.221 -32.361 1.00 53.09 ? 155 VAL C CB 1 ATOM 4102 C CG1 . VAL C 3 157 ? -10.792 77.111 -31.899 1.00 51.49 ? 155 VAL C CG1 1 ATOM 4103 C CG2 . VAL C 3 157 ? -10.658 79.475 -32.683 1.00 53.38 ? 155 VAL C CG2 1 ATOM 4104 N N . TYR C 3 158 ? -8.340 76.498 -30.016 1.00 46.19 ? 156 TYR C N 1 ATOM 4105 C CA . TYR C 3 158 ? -7.653 75.255 -29.662 1.00 42.03 ? 156 TYR C CA 1 ATOM 4106 C C . TYR C 3 158 ? -8.636 74.123 -29.722 1.00 40.84 ? 156 TYR C C 1 ATOM 4107 O O . TYR C 3 158 ? -9.716 74.208 -29.146 1.00 42.63 ? 156 TYR C O 1 ATOM 4108 C CB . TYR C 3 158 ? -7.025 75.352 -28.265 1.00 39.96 ? 156 TYR C CB 1 ATOM 4109 C CG . TYR C 3 158 ? -6.155 76.577 -28.131 1.00 39.69 ? 156 TYR C CG 1 ATOM 4110 C CD1 . TYR C 3 158 ? -4.836 76.586 -28.607 1.00 38.20 ? 156 TYR C CD1 1 ATOM 4111 C CD2 . TYR C 3 158 ? -6.668 77.751 -27.579 1.00 39.58 ? 156 TYR C CD2 1 ATOM 4112 C CE1 . TYR C 3 158 ? -4.044 77.729 -28.507 1.00 38.09 ? 156 TYR C CE1 1 ATOM 4113 C CE2 . TYR C 3 158 ? -5.889 78.897 -27.473 1.00 40.10 ? 156 TYR C CE2 1 ATOM 4114 C CZ . TYR C 3 158 ? -4.583 78.882 -27.937 1.00 39.58 ? 156 TYR C CZ 1 ATOM 4115 O OH . TYR C 3 158 ? -3.838 80.030 -27.819 1.00 38.87 ? 156 TYR C OH 1 ATOM 4116 N N . ILE C 3 159 ? -8.275 73.073 -30.447 1.00 39.92 ? 157 ILE C N 1 ATOM 4117 C CA . ILE C 3 159 ? -9.092 71.873 -30.509 1.00 39.70 ? 157 ILE C CA 1 ATOM 4118 C C . ILE C 3 159 ? -8.203 70.695 -30.194 1.00 37.96 ? 157 ILE C C 1 ATOM 4119 O O . ILE C 3 159 ? -7.164 70.550 -30.817 1.00 36.84 ? 157 ILE C O 1 ATOM 4120 C CB . ILE C 3 159 ? -9.725 71.678 -31.902 1.00 41.98 ? 157 ILE C CB 1 ATOM 4121 C CG1 . ILE C 3 159 ? -10.596 72.886 -32.261 1.00 43.03 ? 157 ILE C CG1 1 ATOM 4122 C CG2 . ILE C 3 159 ? -10.535 70.366 -31.949 1.00 41.90 ? 157 ILE C CG2 1 ATOM 4123 C CD1 . ILE C 3 159 ? -11.286 72.791 -33.596 1.00 46.71 ? 157 ILE C CD1 1 ATOM 4124 N N . THR C 3 160 ? -8.603 69.882 -29.216 1.00 38.36 ? 158 THR C N 1 ATOM 4125 C CA . THR C 3 160 ? -7.862 68.671 -28.851 1.00 41.08 ? 158 THR C CA 1 ATOM 4126 C C . THR C 3 160 ? -8.226 67.532 -29.796 1.00 43.44 ? 158 THR C C 1 ATOM 4127 O O . THR C 3 160 ? -9.259 67.586 -30.464 1.00 44.24 ? 158 THR C O 1 ATOM 4128 C CB . THR C 3 160 ? -8.146 68.213 -27.397 1.00 41.98 ? 158 THR C CB 1 ATOM 4129 O OG1 . THR C 3 160 ? -9.385 67.488 -27.333 1.00 42.48 ? 158 THR C OG1 1 ATOM 4130 C CG2 . THR C 3 160 ? -8.188 69.397 -26.442 1.00 43.04 ? 158 THR C CG2 1 ATOM 4131 N N . ASP C 3 161 ? -7.387 66.504 -29.865 1.00 44.78 ? 159 ASP C N 1 ATOM 4132 C CA . ASP C 3 161 ? -7.740 65.360 -30.682 1.00 48.13 ? 159 ASP C CA 1 ATOM 4133 C C . ASP C 3 161 ? -8.721 64.475 -29.919 1.00 49.14 ? 159 ASP C C 1 ATOM 4134 O O . ASP C 3 161 ? -8.789 64.532 -28.690 1.00 48.54 ? 159 ASP C O 1 ATOM 4135 C CB . ASP C 3 161 ? -6.509 64.574 -31.146 1.00 50.51 ? 159 ASP C CB 1 ATOM 4136 C CG . ASP C 3 161 ? -6.849 63.540 -32.237 1.00 56.07 ? 159 ASP C CG 1 ATOM 4137 O OD1 . ASP C 3 161 ? -7.809 63.767 -33.028 1.00 54.91 ? 159 ASP C OD1 1 ATOM 4138 O OD2 . ASP C 3 161 ? -6.157 62.495 -32.299 1.00 57.10 ? 159 ASP C OD2 1 ATOM 4139 N N . LYS C 3 162 ? -9.488 63.668 -30.653 1.00 50.04 ? 160 LYS C N 1 ATOM 4140 C CA . LYS C 3 162 ? -10.461 62.771 -30.041 1.00 47.65 ? 160 LYS C CA 1 ATOM 4141 C C . LYS C 3 162 ? -9.813 61.866 -29.000 1.00 45.06 ? 160 LYS C C 1 ATOM 4142 O O . LYS C 3 162 ? -8.618 61.586 -29.062 1.00 44.44 ? 160 LYS C O 1 ATOM 4143 C CB . LYS C 3 162 ? -11.226 61.949 -31.093 1.00 50.23 ? 160 LYS C CB 1 ATOM 4144 C CG . LYS C 3 162 ? -10.408 60.920 -31.875 1.00 51.49 ? 160 LYS C CG 1 ATOM 4145 C CD . LYS C 3 162 ? -11.319 60.069 -32.760 1.00 52.40 ? 160 LYS C CD 1 ATOM 4146 C CE . LYS C 3 162 ? -10.667 59.767 -34.105 1.00 53.53 ? 160 LYS C CE 1 ATOM 4147 N NZ . LYS C 3 162 ? -11.521 58.889 -34.954 1.00 55.90 ? 160 LYS C NZ 1 ATOM 4148 N N . CYS C 3 163 ? -10.625 61.423 -28.050 1.00 41.96 ? 161 CYS C N 1 ATOM 4149 C CA . CYS C 3 163 ? -10.177 60.646 -26.921 1.00 39.37 ? 161 CYS C CA 1 ATOM 4150 C C . CYS C 3 163 ? -11.382 59.824 -26.481 1.00 37.50 ? 161 CYS C C 1 ATOM 4151 O O . CYS C 3 163 ? -12.505 60.327 -26.502 1.00 40.48 ? 161 CYS C O 1 ATOM 4152 C CB . CYS C 3 163 ? -9.736 61.612 -25.823 1.00 42.93 ? 161 CYS C CB 1 ATOM 4153 S SG . CYS C 3 163 ? -9.276 60.865 -24.264 1.00 51.56 ? 161 CYS C SG 1 ATOM 4154 N N . VAL C 3 164 ? -11.166 58.571 -26.089 1.00 32.64 ? 162 VAL C N 1 ATOM 4155 C CA . VAL C 3 164 ? -12.272 57.696 -25.698 1.00 31.50 ? 162 VAL C CA 1 ATOM 4156 C C . VAL C 3 164 ? -12.321 57.332 -24.204 1.00 31.92 ? 162 VAL C C 1 ATOM 4157 O O . VAL C 3 164 ? -11.357 56.812 -23.632 1.00 31.59 ? 162 VAL C O 1 ATOM 4158 C CB . VAL C 3 164 ? -12.332 56.419 -26.592 1.00 32.57 ? 162 VAL C CB 1 ATOM 4159 C CG1 . VAL C 3 164 ? -10.933 55.768 -26.745 1.00 33.66 ? 162 VAL C CG1 1 ATOM 4160 C CG2 . VAL C 3 164 ? -13.388 55.418 -26.083 1.00 30.89 ? 162 VAL C CG2 1 ATOM 4161 N N . LEU C 3 165 ? -13.462 57.599 -23.579 1.00 32.54 ? 163 LEU C N 1 ATOM 4162 C CA . LEU C 3 165 ? -13.649 57.270 -22.174 1.00 32.92 ? 163 LEU C CA 1 ATOM 4163 C C . LEU C 3 165 ? -14.590 56.077 -22.003 1.00 34.39 ? 163 LEU C C 1 ATOM 4164 O O . LEU C 3 165 ? -15.511 55.877 -22.790 1.00 33.86 ? 163 LEU C O 1 ATOM 4165 C CB . LEU C 3 165 ? -14.159 58.489 -21.395 1.00 32.88 ? 163 LEU C CB 1 ATOM 4166 C CG . LEU C 3 165 ? -15.572 59.051 -21.637 1.00 32.23 ? 163 LEU C CG 1 ATOM 4167 C CD1 . LEU C 3 165 ? -16.645 58.190 -20.942 1.00 31.97 ? 163 LEU C CD1 1 ATOM 4168 C CD2 . LEU C 3 165 ? -15.657 60.489 -21.153 1.00 30.16 ? 163 LEU C CD2 1 ATOM 4169 N N . ASP C 3 166 ? -14.360 55.311 -20.945 1.00 36.86 ? 164 ASP C N 1 ATOM 4170 C CA . ASP C 3 166 ? -15.104 54.095 -20.679 1.00 37.81 ? 164 ASP C CA 1 ATOM 4171 C C . ASP C 3 166 ? -15.731 54.174 -19.302 1.00 38.06 ? 164 ASP C C 1 ATOM 4172 O O . ASP C 3 166 ? -15.031 54.143 -18.292 1.00 37.21 ? 164 ASP C O 1 ATOM 4173 C CB . ASP C 3 166 ? -14.178 52.874 -20.777 1.00 39.52 ? 164 ASP C CB 1 ATOM 4174 C CG . ASP C 3 166 ? -14.911 51.553 -20.578 1.00 42.09 ? 164 ASP C CG 1 ATOM 4175 O OD1 . ASP C 3 166 ? -16.144 51.557 -20.362 1.00 43.43 ? 164 ASP C OD1 1 ATOM 4176 O OD2 . ASP C 3 166 ? -14.248 50.495 -20.645 1.00 43.74 ? 164 ASP C OD2 1 ATOM 4177 N N . MET C 3 167 ? -17.056 54.284 -19.270 1.00 39.46 ? 165 MET C N 1 ATOM 4178 C CA . MET C 3 167 ? -17.803 54.182 -18.020 1.00 40.84 ? 165 MET C CA 1 ATOM 4179 C C . MET C 3 167 ? -17.951 52.701 -17.709 1.00 40.53 ? 165 MET C C 1 ATOM 4180 O O . MET C 3 167 ? -18.940 52.081 -18.100 1.00 41.33 ? 165 MET C O 1 ATOM 4181 C CB . MET C 3 167 ? -19.164 54.883 -18.136 1.00 40.58 ? 165 MET C CB 1 ATOM 4182 C CG . MET C 3 167 ? -19.043 56.394 -18.186 1.00 41.46 ? 165 MET C CG 1 ATOM 4183 S SD . MET C 3 167 ? -20.478 57.330 -18.754 1.00 44.68 ? 165 MET C SD 1 ATOM 4184 C CE . MET C 3 167 ? -21.421 57.482 -17.231 1.00 42.02 ? 165 MET C CE 1 ATOM 4185 N N . ARG C 3 168 ? -16.948 52.136 -17.036 1.00 40.46 ? 166 ARG C N 1 ATOM 4186 C CA . ARG C 3 168 ? -16.868 50.680 -16.831 1.00 42.56 ? 166 ARG C CA 1 ATOM 4187 C C . ARG C 3 168 ? -18.164 50.081 -16.250 1.00 43.38 ? 166 ARG C C 1 ATOM 4188 O O . ARG C 3 168 ? -18.720 49.151 -16.825 1.00 40.27 ? 166 ARG C O 1 ATOM 4189 C CB . ARG C 3 168 ? -15.630 50.299 -16.002 1.00 40.61 ? 166 ARG C CB 1 ATOM 4190 N N . SER C 3 169 ? -18.652 50.653 -15.147 1.00 49.32 ? 167 SER C N 1 ATOM 4191 C CA . SER C 3 169 ? -19.903 50.230 -14.468 1.00 53.67 ? 167 SER C CA 1 ATOM 4192 C C . SER C 3 169 ? -21.146 50.143 -15.362 1.00 54.44 ? 167 SER C C 1 ATOM 4193 O O . SER C 3 169 ? -21.960 49.238 -15.195 1.00 56.94 ? 167 SER C O 1 ATOM 4194 C CB . SER C 3 169 ? -20.217 51.157 -13.285 1.00 55.52 ? 167 SER C CB 1 ATOM 4195 O OG . SER C 3 169 ? -20.589 52.456 -13.739 1.00 59.70 ? 167 SER C OG 1 ATOM 4196 N N . MET C 3 170 ? -21.298 51.097 -16.279 1.00 54.47 ? 168 MET C N 1 ATOM 4197 C CA . MET C 3 170 ? -22.396 51.100 -17.252 1.00 56.02 ? 168 MET C CA 1 ATOM 4198 C C . MET C 3 170 ? -22.101 50.313 -18.531 1.00 55.26 ? 168 MET C C 1 ATOM 4199 O O . MET C 3 170 ? -22.973 50.185 -19.385 1.00 52.68 ? 168 MET C O 1 ATOM 4200 C CB . MET C 3 170 ? -22.731 52.536 -17.647 1.00 58.80 ? 168 MET C CB 1 ATOM 4201 C CG . MET C 3 170 ? -24.045 53.056 -17.104 1.00 62.86 ? 168 MET C CG 1 ATOM 4202 S SD . MET C 3 170 ? -24.064 54.865 -17.053 1.00 67.89 ? 168 MET C SD 1 ATOM 4203 C CE . MET C 3 170 ? -23.443 55.139 -15.378 1.00 65.93 ? 168 MET C CE 1 ATOM 4204 N N . ASP C 3 171 ? -20.876 49.797 -18.651 1.00 57.63 ? 169 ASP C N 1 ATOM 4205 C CA . ASP C 3 171 ? -20.339 49.248 -19.907 1.00 56.81 ? 169 ASP C CA 1 ATOM 4206 C C . ASP C 3 171 ? -20.652 50.197 -21.055 1.00 52.39 ? 169 ASP C C 1 ATOM 4207 O O . ASP C 3 171 ? -21.457 49.895 -21.927 1.00 55.78 ? 169 ASP C O 1 ATOM 4208 C CB . ASP C 3 171 ? -20.860 47.826 -20.191 1.00 62.66 ? 169 ASP C CB 1 ATOM 4209 C CG . ASP C 3 171 ? -19.913 47.012 -21.091 1.00 70.12 ? 169 ASP C CG 1 ATOM 4210 O OD1 . ASP C 3 171 ? -19.474 45.921 -20.656 1.00 72.04 ? 169 ASP C OD1 1 ATOM 4211 O OD2 . ASP C 3 171 ? -19.604 47.456 -22.225 1.00 70.17 ? 169 ASP C OD2 1 ATOM 4212 N N . PHE C 3 172 ? -20.014 51.356 -21.040 1.00 46.93 ? 170 PHE C N 1 ATOM 4213 C CA . PHE C 3 172 ? -20.327 52.392 -21.997 1.00 44.55 ? 170 PHE C CA 1 ATOM 4214 C C . PHE C 3 172 ? -19.062 53.109 -22.443 1.00 43.95 ? 170 PHE C C 1 ATOM 4215 O O . PHE C 3 172 ? -18.306 53.610 -21.615 1.00 46.26 ? 170 PHE C O 1 ATOM 4216 C CB . PHE C 3 172 ? -21.310 53.379 -21.364 1.00 45.88 ? 170 PHE C CB 1 ATOM 4217 C CG . PHE C 3 172 ? -21.642 54.547 -22.235 1.00 45.45 ? 170 PHE C CG 1 ATOM 4218 C CD1 . PHE C 3 172 ? -22.689 54.469 -23.156 1.00 45.64 ? 170 PHE C CD1 1 ATOM 4219 C CD2 . PHE C 3 172 ? -20.913 55.729 -22.139 1.00 44.66 ? 170 PHE C CD2 1 ATOM 4220 C CE1 . PHE C 3 172 ? -23.003 55.558 -23.979 1.00 45.14 ? 170 PHE C CE1 1 ATOM 4221 C CE2 . PHE C 3 172 ? -21.216 56.820 -22.957 1.00 45.88 ? 170 PHE C CE2 1 ATOM 4222 C CZ . PHE C 3 172 ? -22.263 56.734 -23.879 1.00 45.06 ? 170 PHE C CZ 1 ATOM 4223 N N . LYS C 3 173 ? -18.833 53.150 -23.751 1.00 41.99 ? 171 LYS C N 1 ATOM 4224 C CA . LYS C 3 173 ? -17.714 53.897 -24.315 1.00 40.77 ? 171 LYS C CA 1 ATOM 4225 C C . LYS C 3 173 ? -18.230 55.097 -25.108 1.00 39.12 ? 171 LYS C C 1 ATOM 4226 O O . LYS C 3 173 ? -19.315 55.023 -25.686 1.00 38.44 ? 171 LYS C O 1 ATOM 4227 C CB . LYS C 3 173 ? -16.841 52.986 -25.188 1.00 42.66 ? 171 LYS C CB 1 ATOM 4228 C CG . LYS C 3 173 ? -15.905 52.084 -24.388 1.00 44.17 ? 171 LYS C CG 1 ATOM 4229 C CD . LYS C 3 173 ? -15.646 50.755 -25.084 1.00 46.21 ? 171 LYS C CD 1 ATOM 4230 C CE . LYS C 3 173 ? -14.714 49.851 -24.246 1.00 48.30 ? 171 LYS C CE 1 ATOM 4231 N NZ . LYS C 3 173 ? -15.341 49.284 -23.000 1.00 48.05 ? 171 LYS C NZ 1 ATOM 4232 N N . SER C 3 174 ? -17.465 56.198 -25.102 1.00 36.97 ? 172 SER C N 1 ATOM 4233 C CA . SER C 3 174 ? -17.785 57.421 -25.857 1.00 35.06 ? 172 SER C CA 1 ATOM 4234 C C . SER C 3 174 ? -16.548 58.245 -26.232 1.00 35.27 ? 172 SER C C 1 ATOM 4235 O O . SER C 3 174 ? -15.610 58.399 -25.438 1.00 33.93 ? 172 SER C O 1 ATOM 4236 C CB . SER C 3 174 ? -18.808 58.295 -25.110 1.00 35.11 ? 172 SER C CB 1 ATOM 4237 O OG . SER C 3 174 ? -18.213 59.210 -24.204 1.00 33.82 ? 172 SER C OG 1 ATOM 4238 N N . ASN C 3 175 ? -16.569 58.766 -27.455 1.00 36.65 ? 173 ASN C N 1 ATOM 4239 C CA . ASN C 3 175 ? -15.516 59.623 -27.993 1.00 37.61 ? 173 ASN C CA 1 ATOM 4240 C C . ASN C 3 175 ? -15.837 61.067 -27.676 1.00 38.06 ? 173 ASN C C 1 ATOM 4241 O O . ASN C 3 175 ? -17.015 61.432 -27.541 1.00 39.74 ? 173 ASN C O 1 ATOM 4242 C CB . ASN C 3 175 ? -15.475 59.499 -29.518 1.00 40.68 ? 173 ASN C CB 1 ATOM 4243 C CG . ASN C 3 175 ? -14.482 58.476 -30.006 1.00 42.78 ? 173 ASN C CG 1 ATOM 4244 O OD1 . ASN C 3 175 ? -13.292 58.524 -29.665 1.00 45.21 ? 173 ASN C OD1 1 ATOM 4245 N ND2 . ASN C 3 175 ? -14.957 57.556 -30.845 1.00 42.57 ? 173 ASN C ND2 1 ATOM 4246 N N . SER C 3 176 ? -14.808 61.903 -27.584 1.00 35.50 ? 174 SER C N 1 ATOM 4247 C CA . SER C 3 176 ? -15.032 63.337 -27.404 1.00 34.74 ? 174 SER C CA 1 ATOM 4248 C C . SER C 3 176 ? -13.829 64.188 -27.814 1.00 35.44 ? 174 SER C C 1 ATOM 4249 O O . SER C 3 176 ? -12.689 63.702 -27.875 1.00 37.30 ? 174 SER C O 1 ATOM 4250 C CB . SER C 3 176 ? -15.451 63.657 -25.965 1.00 33.86 ? 174 SER C CB 1 ATOM 4251 O OG . SER C 3 176 ? -14.388 63.418 -25.067 1.00 33.48 ? 174 SER C OG 1 ATOM 4252 N N . ALA C 3 177 ? -14.103 65.453 -28.121 1.00 32.90 ? 175 ALA C N 1 ATOM 4253 C CA . ALA C 3 177 ? -13.062 66.433 -28.338 1.00 31.59 ? 175 ALA C CA 1 ATOM 4254 C C . ALA C 3 177 ? -13.514 67.720 -27.674 1.00 31.49 ? 175 ALA C C 1 ATOM 4255 O O . ALA C 3 177 ? -14.710 67.935 -27.462 1.00 30.19 ? 175 ALA C O 1 ATOM 4256 C CB . ALA C 3 177 ? -12.821 66.639 -29.815 1.00 31.65 ? 175 ALA C CB 1 ATOM 4257 N N . VAL C 3 178 ? -12.545 68.560 -27.332 1.00 31.93 ? 176 VAL C N 1 ATOM 4258 C CA . VAL C 3 178 ? -12.796 69.822 -26.648 1.00 32.09 ? 176 VAL C CA 1 ATOM 4259 C C . VAL C 3 178 ? -12.191 70.945 -27.484 1.00 32.86 ? 176 VAL C C 1 ATOM 4260 O O . VAL C 3 178 ? -11.087 70.806 -28.032 1.00 33.51 ? 176 VAL C O 1 ATOM 4261 C CB . VAL C 3 178 ? -12.175 69.820 -25.216 1.00 31.67 ? 176 VAL C CB 1 ATOM 4262 C CG1 . VAL C 3 178 ? -12.613 71.048 -24.409 1.00 31.24 ? 176 VAL C CG1 1 ATOM 4263 C CG2 . VAL C 3 178 ? -12.556 68.550 -24.473 1.00 31.94 ? 176 VAL C CG2 1 ATOM 4264 N N . ALA C 3 179 ? -12.914 72.054 -27.590 1.00 33.27 ? 177 ALA C N 1 ATOM 4265 C CA . ALA C 3 179 ? -12.398 73.222 -28.287 1.00 34.09 ? 177 ALA C CA 1 ATOM 4266 C C . ALA C 3 179 ? -12.673 74.468 -27.468 1.00 34.83 ? 177 ALA C C 1 ATOM 4267 O O . ALA C 3 179 ? -13.695 74.541 -26.786 1.00 34.97 ? 177 ALA C O 1 ATOM 4268 C CB . ALA C 3 179 ? -13.022 73.336 -29.662 1.00 35.07 ? 177 ALA C CB 1 ATOM 4269 N N . TRP C 3 180 ? -11.751 75.430 -27.519 1.00 36.03 ? 178 TRP C N 1 ATOM 4270 C CA . TRP C 3 180 ? -11.936 76.731 -26.864 1.00 39.18 ? 178 TRP C CA 1 ATOM 4271 C C . TRP C 3 180 ? -11.157 77.819 -27.553 1.00 43.98 ? 178 TRP C C 1 ATOM 4272 O O . TRP C 3 180 ? -10.433 77.560 -28.521 1.00 44.04 ? 178 TRP C O 1 ATOM 4273 C CB . TRP C 3 180 ? -11.584 76.675 -25.371 1.00 37.60 ? 178 TRP C CB 1 ATOM 4274 C CG . TRP C 3 180 ? -10.133 76.355 -25.083 1.00 36.10 ? 178 TRP C CG 1 ATOM 4275 C CD1 . TRP C 3 180 ? -9.109 77.246 -24.751 1.00 35.34 ? 178 TRP C CD1 1 ATOM 4276 C CD2 . TRP C 3 180 ? -9.492 75.028 -25.106 1.00 36.03 ? 178 TRP C CD2 1 ATOM 4277 N NE1 . TRP C 3 180 ? -7.915 76.581 -24.573 1.00 35.25 ? 178 TRP C NE1 1 ATOM 4278 C CE2 . TRP C 3 180 ? -8.074 75.251 -24.773 1.00 35.54 ? 178 TRP C CE2 1 ATOM 4279 C CE3 . TRP C 3 180 ? -9.933 73.727 -25.365 1.00 35.10 ? 178 TRP C CE3 1 ATOM 4280 C CZ2 . TRP C 3 180 ? -7.166 74.204 -24.700 1.00 35.70 ? 178 TRP C CZ2 1 ATOM 4281 C CZ3 . TRP C 3 180 ? -9.004 72.680 -25.299 1.00 35.04 ? 178 TRP C CZ3 1 ATOM 4282 C CH2 . TRP C 3 180 ? -7.656 72.913 -24.970 1.00 35.74 ? 178 TRP C CH2 1 ATOM 4283 N N . SER C 3 181 ? -11.315 79.041 -27.040 1.00 49.98 ? 179 SER C N 1 ATOM 4284 C CA . SER C 3 181 ? -10.665 80.256 -27.531 1.00 55.21 ? 179 SER C CA 1 ATOM 4285 C C . SER C 3 181 ? -11.374 81.432 -26.872 1.00 62.01 ? 179 SER C C 1 ATOM 4286 O O . SER C 3 181 ? -12.596 81.573 -27.005 1.00 67.21 ? 179 SER C O 1 ATOM 4287 C CB . SER C 3 181 ? -10.805 80.379 -29.049 1.00 54.89 ? 179 SER C CB 1 ATOM 4288 O OG . SER C 3 181 ? -10.246 81.591 -29.528 1.00 54.91 ? 179 SER C OG 1 ATOM 4289 N N . ASN C 3 182 ? -10.634 82.274 -26.159 1.00 64.93 ? 180 ASN C N 1 ATOM 4290 C CA . ASN C 3 182 ? -11.255 83.455 -25.549 1.00 70.06 ? 180 ASN C CA 1 ATOM 4291 C C . ASN C 3 182 ? -11.493 84.589 -26.567 1.00 70.49 ? 180 ASN C C 1 ATOM 4292 O O . ASN C 3 182 ? -12.601 85.144 -26.650 1.00 67.44 ? 180 ASN C O 1 ATOM 4293 C CB . ASN C 3 182 ? -10.479 83.928 -24.306 1.00 70.61 ? 180 ASN C CB 1 ATOM 4294 C CG . ASN C 3 182 ? -9.016 84.199 -24.595 1.00 72.96 ? 180 ASN C CG 1 ATOM 4295 O OD1 . ASN C 3 182 ? -8.660 85.243 -25.151 1.00 72.72 ? 180 ASN C OD1 1 ATOM 4296 N ND2 . ASN C 3 182 ? -8.156 83.257 -24.215 1.00 73.52 ? 180 ASN C ND2 1 ATOM 4297 N N . LYS C 3 183 ? -10.460 84.904 -27.350 1.00 69.39 ? 181 LYS C N 1 ATOM 4298 C CA . LYS C 3 183 ? -10.548 85.932 -28.384 1.00 70.36 ? 181 LYS C CA 1 ATOM 4299 C C . LYS C 3 183 ? -11.254 85.377 -29.619 1.00 68.47 ? 181 LYS C C 1 ATOM 4300 O O . LYS C 3 183 ? -12.392 84.917 -29.536 1.00 65.34 ? 181 LYS C O 1 ATOM 4301 C CB . LYS C 3 183 ? -9.153 86.471 -28.743 1.00 69.13 ? 181 LYS C CB 1 ATOM 4302 N N . ASP C 3 185 ? -17.276 86.472 -29.105 1.00 77.90 ? 183 ASP C N 1 ATOM 4303 C CA . ASP C 3 185 ? -17.436 86.314 -30.549 1.00 81.07 ? 183 ASP C CA 1 ATOM 4304 C C . ASP C 3 185 ? -17.339 84.847 -30.993 1.00 81.26 ? 183 ASP C C 1 ATOM 4305 O O . ASP C 3 185 ? -18.073 84.419 -31.888 1.00 79.28 ? 183 ASP C O 1 ATOM 4306 C CB . ASP C 3 185 ? -16.427 87.187 -31.306 1.00 81.97 ? 183 ASP C CB 1 ATOM 4307 C CG . ASP C 3 185 ? -14.986 86.874 -30.933 1.00 85.37 ? 183 ASP C CG 1 ATOM 4308 O OD1 . ASP C 3 185 ? -14.384 87.658 -30.168 1.00 84.13 ? 183 ASP C OD1 1 ATOM 4309 O OD2 . ASP C 3 185 ? -14.460 85.837 -31.398 1.00 86.24 ? 183 ASP C OD2 1 ATOM 4310 N N . PHE C 3 186 ? -16.428 84.097 -30.364 1.00 80.52 ? 184 PHE C N 1 ATOM 4311 C CA . PHE C 3 186 ? -16.258 82.652 -30.587 1.00 75.15 ? 184 PHE C CA 1 ATOM 4312 C C . PHE C 3 186 ? -17.461 81.882 -30.021 1.00 73.41 ? 184 PHE C C 1 ATOM 4313 O O . PHE C 3 186 ? -17.931 82.181 -28.910 1.00 71.20 ? 184 PHE C O 1 ATOM 4314 C CB . PHE C 3 186 ? -14.936 82.173 -29.949 1.00 69.32 ? 184 PHE C CB 1 ATOM 4315 C CG . PHE C 3 186 ? -14.726 80.670 -29.982 1.00 67.48 ? 184 PHE C CG 1 ATOM 4316 C CD1 . PHE C 3 186 ? -14.100 80.061 -31.068 1.00 64.74 ? 184 PHE C CD1 1 ATOM 4317 C CD2 . PHE C 3 186 ? -15.128 79.866 -28.908 1.00 65.67 ? 184 PHE C CD2 1 ATOM 4318 C CE1 . PHE C 3 186 ? -13.893 78.670 -31.093 1.00 63.16 ? 184 PHE C CE1 1 ATOM 4319 C CE2 . PHE C 3 186 ? -14.925 78.473 -28.927 1.00 63.65 ? 184 PHE C CE2 1 ATOM 4320 C CZ . PHE C 3 186 ? -14.305 77.877 -30.023 1.00 61.00 ? 184 PHE C CZ 1 ATOM 4321 N N . ALA C 3 187 ? -17.957 80.908 -30.791 1.00 68.11 ? 185 ALA C N 1 ATOM 4322 C CA . ALA C 3 187 ? -19.107 80.096 -30.374 1.00 65.35 ? 185 ALA C CA 1 ATOM 4323 C C . ALA C 3 187 ? -19.113 78.675 -30.937 1.00 62.85 ? 185 ALA C C 1 ATOM 4324 O O . ALA C 3 187 ? -18.319 78.317 -31.810 1.00 58.60 ? 185 ALA C O 1 ATOM 4325 C CB . ALA C 3 187 ? -20.429 80.813 -30.682 1.00 64.53 ? 185 ALA C CB 1 ATOM 4326 N N . CYS C 3 188 ? -20.051 77.885 -30.428 1.00 66.30 ? 186 CYS C N 1 ATOM 4327 C CA . CYS C 3 188 ? -20.061 76.439 -30.606 1.00 70.46 ? 186 CYS C CA 1 ATOM 4328 C C . CYS C 3 188 ? -20.427 75.893 -31.992 1.00 72.89 ? 186 CYS C C 1 ATOM 4329 O O . CYS C 3 188 ? -19.959 74.815 -32.377 1.00 74.97 ? 186 CYS C O 1 ATOM 4330 C CB . CYS C 3 188 ? -20.882 75.784 -29.489 1.00 72.95 ? 186 CYS C CB 1 ATOM 4331 S SG . CYS C 3 188 ? -19.850 75.473 -28.016 1.00 81.90 ? 186 CYS C SG 1 ATOM 4332 N N . ALA C 3 189 ? -21.248 76.623 -32.742 1.00 72.56 ? 187 ALA C N 1 ATOM 4333 C CA . ALA C 3 189 ? -21.492 76.268 -34.138 1.00 69.98 ? 187 ALA C CA 1 ATOM 4334 C C . ALA C 3 189 ? -20.222 76.475 -34.956 1.00 70.86 ? 187 ALA C C 1 ATOM 4335 O O . ALA C 3 189 ? -19.961 75.734 -35.900 1.00 71.75 ? 187 ALA C O 1 ATOM 4336 C CB . ALA C 3 189 ? -22.626 77.086 -34.708 1.00 69.06 ? 187 ALA C CB 1 ATOM 4337 N N . ASN C 3 190 ? -19.432 77.479 -34.576 1.00 73.63 ? 188 ASN C N 1 ATOM 4338 C CA . ASN C 3 190 ? -18.202 77.834 -35.291 1.00 74.96 ? 188 ASN C CA 1 ATOM 4339 C C . ASN C 3 190 ? -17.032 76.910 -34.994 1.00 72.02 ? 188 ASN C C 1 ATOM 4340 O O . ASN C 3 190 ? -16.117 76.770 -35.811 1.00 73.80 ? 188 ASN C O 1 ATOM 4341 C CB . ASN C 3 190 ? -17.790 79.279 -34.973 1.00 77.14 ? 188 ASN C CB 1 ATOM 4342 C CG . ASN C 3 190 ? -18.532 80.305 -35.821 1.00 81.67 ? 188 ASN C CG 1 ATOM 4343 O OD1 . ASN C 3 190 ? -19.726 80.154 -36.109 1.00 81.76 ? 188 ASN C OD1 1 ATOM 4344 N ND2 . ASN C 3 190 ? -17.824 81.363 -36.223 1.00 79.09 ? 188 ASN C ND2 1 ATOM 4345 N N . ALA C 3 191 ? -17.075 76.286 -33.822 1.00 67.07 ? 189 ALA C N 1 ATOM 4346 C CA . ALA C 3 191 ? -15.934 75.570 -33.274 1.00 61.82 ? 189 ALA C CA 1 ATOM 4347 C C . ALA C 3 191 ? -15.378 74.471 -34.182 1.00 60.51 ? 189 ALA C C 1 ATOM 4348 O O . ALA C 3 191 ? -14.176 74.434 -34.445 1.00 58.16 ? 189 ALA C O 1 ATOM 4349 C CB . ALA C 3 191 ? -16.287 75.012 -31.918 1.00 63.69 ? 189 ALA C CB 1 ATOM 4350 N N . PHE C 3 192 ? -16.249 73.589 -34.669 1.00 59.62 ? 190 PHE C N 1 ATOM 4351 C CA . PHE C 3 192 ? -15.795 72.414 -35.417 1.00 60.25 ? 190 PHE C CA 1 ATOM 4352 C C . PHE C 3 192 ? -16.026 72.480 -36.938 1.00 63.00 ? 190 PHE C C 1 ATOM 4353 O O . PHE C 3 192 ? -15.994 71.451 -37.622 1.00 62.46 ? 190 PHE C O 1 ATOM 4354 C CB . PHE C 3 192 ? -16.393 71.140 -34.810 1.00 58.73 ? 190 PHE C CB 1 ATOM 4355 C CG . PHE C 3 192 ? -15.982 70.902 -33.382 1.00 58.95 ? 190 PHE C CG 1 ATOM 4356 C CD1 . PHE C 3 192 ? -16.752 71.394 -32.328 1.00 59.34 ? 190 PHE C CD1 1 ATOM 4357 C CD2 . PHE C 3 192 ? -14.823 70.188 -33.087 1.00 58.27 ? 190 PHE C CD2 1 ATOM 4358 C CE1 . PHE C 3 192 ? -16.370 71.187 -31.010 1.00 58.67 ? 190 PHE C CE1 1 ATOM 4359 C CE2 . PHE C 3 192 ? -14.435 69.969 -31.769 1.00 57.13 ? 190 PHE C CE2 1 ATOM 4360 C CZ . PHE C 3 192 ? -15.205 70.472 -30.730 1.00 58.32 ? 190 PHE C CZ 1 ATOM 4361 N N . ASN C 3 193 ? -16.226 73.695 -37.456 1.00 65.86 ? 191 ASN C N 1 ATOM 4362 C CA . ASN C 3 193 ? -16.388 73.947 -38.897 1.00 67.00 ? 191 ASN C CA 1 ATOM 4363 C C . ASN C 3 193 ? -15.374 73.234 -39.800 1.00 66.16 ? 191 ASN C C 1 ATOM 4364 O O . ASN C 3 193 ? -15.726 72.794 -40.895 1.00 64.57 ? 191 ASN C O 1 ATOM 4365 C CB . ASN C 3 193 ? -16.362 75.454 -39.190 1.00 69.08 ? 191 ASN C CB 1 ATOM 4366 C CG . ASN C 3 193 ? -17.643 76.158 -38.770 1.00 72.51 ? 191 ASN C CG 1 ATOM 4367 O OD1 . ASN C 3 193 ? -18.665 75.520 -38.505 1.00 71.95 ? 191 ASN C OD1 1 ATOM 4368 N ND2 . ASN C 3 193 ? -17.592 77.485 -38.712 1.00 72.62 ? 191 ASN C ND2 1 ATOM 4369 N N . ASN C 3 194 ? -14.129 73.121 -39.337 1.00 64.59 ? 192 ASN C N 1 ATOM 4370 C CA . ASN C 3 194 ? -13.064 72.497 -40.124 1.00 65.50 ? 192 ASN C CA 1 ATOM 4371 C C . ASN C 3 194 ? -13.000 70.956 -40.027 1.00 63.02 ? 192 ASN C C 1 ATOM 4372 O O . ASN C 3 194 ? -12.005 70.350 -40.425 1.00 61.35 ? 192 ASN C O 1 ATOM 4373 C CB . ASN C 3 194 ? -11.704 73.128 -39.777 1.00 68.71 ? 192 ASN C CB 1 ATOM 4374 C CG . ASN C 3 194 ? -10.783 73.258 -40.994 1.00 70.95 ? 192 ASN C CG 1 ATOM 4375 O OD1 . ASN C 3 194 ? -11.076 73.997 -41.939 1.00 72.78 ? 192 ASN C OD1 1 ATOM 4376 N ND2 . ASN C 3 194 ? -9.658 72.554 -40.963 1.00 68.81 ? 192 ASN C ND2 1 ATOM 4377 N N . SER C 3 195 ? -14.060 70.331 -39.515 1.00 62.41 ? 193 SER C N 1 ATOM 4378 C CA . SER C 3 195 ? -14.110 68.870 -39.362 1.00 63.87 ? 193 SER C CA 1 ATOM 4379 C C . SER C 3 195 ? -15.304 68.244 -40.083 1.00 65.35 ? 193 SER C C 1 ATOM 4380 O O . SER C 3 195 ? -16.366 68.868 -40.214 1.00 66.85 ? 193 SER C O 1 ATOM 4381 C CB . SER C 3 195 ? -14.156 68.477 -37.875 1.00 63.18 ? 193 SER C CB 1 ATOM 4382 O OG . SER C 3 195 ? -12.913 68.695 -37.222 1.00 61.99 ? 193 SER C OG 1 ATOM 4383 N N . ILE C 3 196 ? -15.133 67.001 -40.530 1.00 66.74 ? 194 ILE C N 1 ATOM 4384 C CA . ILE C 3 196 ? -16.239 66.229 -41.114 1.00 70.26 ? 194 ILE C CA 1 ATOM 4385 C C . ILE C 3 196 ? -17.184 65.654 -40.040 1.00 70.11 ? 194 ILE C C 1 ATOM 4386 O O . ILE C 3 196 ? -17.365 64.434 -39.925 1.00 70.55 ? 194 ILE C O 1 ATOM 4387 C CB . ILE C 3 196 ? -15.752 65.129 -42.128 1.00 74.65 ? 194 ILE C CB 1 ATOM 4388 C CG1 . ILE C 3 196 ? -14.584 64.292 -41.561 1.00 78.87 ? 194 ILE C CG1 1 ATOM 4389 C CG2 . ILE C 3 196 ? -15.374 65.766 -43.477 1.00 70.79 ? 194 ILE C CG2 1 ATOM 4390 C CD1 . ILE C 3 196 ? -14.984 62.948 -40.925 1.00 75.73 ? 194 ILE C CD1 1 ATOM 4391 N N . ILE C 3 197 ? -17.787 66.550 -39.258 1.00 67.77 ? 195 ILE C N 1 ATOM 4392 C CA . ILE C 3 197 ? -18.761 66.154 -38.244 1.00 68.30 ? 195 ILE C CA 1 ATOM 4393 C C . ILE C 3 197 ? -20.010 65.594 -38.936 1.00 70.47 ? 195 ILE C C 1 ATOM 4394 O O . ILE C 3 197 ? -20.427 66.131 -39.963 1.00 71.83 ? 195 ILE C O 1 ATOM 4395 C CB . ILE C 3 197 ? -19.106 67.317 -37.262 1.00 66.02 ? 195 ILE C CB 1 ATOM 4396 C CG1 . ILE C 3 197 ? -19.988 68.380 -37.927 1.00 66.43 ? 195 ILE C CG1 1 ATOM 4397 C CG2 . ILE C 3 197 ? -17.826 67.926 -36.690 1.00 65.52 ? 195 ILE C CG2 1 ATOM 4398 C CD1 . ILE C 3 197 ? -20.483 69.464 -36.984 1.00 64.51 ? 195 ILE C CD1 1 ATOM 4399 N N . PRO C 3 198 ? -20.592 64.500 -38.392 1.00 71.72 ? 196 PRO C N 1 ATOM 4400 C CA . PRO C 3 198 ? -21.739 63.832 -39.019 1.00 73.12 ? 196 PRO C CA 1 ATOM 4401 C C . PRO C 3 198 ? -22.905 64.770 -39.323 1.00 73.60 ? 196 PRO C C 1 ATOM 4402 O O . PRO C 3 198 ? -22.980 65.871 -38.774 1.00 74.94 ? 196 PRO C O 1 ATOM 4403 C CB . PRO C 3 198 ? -22.153 62.790 -37.973 1.00 72.85 ? 196 PRO C CB 1 ATOM 4404 C CG . PRO C 3 198 ? -20.894 62.485 -37.243 1.00 73.60 ? 196 PRO C CG 1 ATOM 4405 C CD . PRO C 3 198 ? -20.175 63.804 -37.158 1.00 73.89 ? 196 PRO C CD 1 ATOM 4406 N N . GLU C 3 199 ? -23.799 64.325 -40.198 1.00 74.45 ? 197 GLU C N 1 ATOM 4407 C CA . GLU C 3 199 ? -24.927 65.135 -40.627 1.00 75.10 ? 197 GLU C CA 1 ATOM 4408 C C . GLU C 3 199 ? -25.969 65.308 -39.517 1.00 72.02 ? 197 GLU C C 1 ATOM 4409 O O . GLU C 3 199 ? -26.556 66.385 -39.371 1.00 68.09 ? 197 GLU C O 1 ATOM 4410 C CB . GLU C 3 199 ? -25.558 64.528 -41.882 1.00 80.76 ? 197 GLU C CB 1 ATOM 4411 C CG . GLU C 3 199 ? -26.288 65.544 -42.751 1.00 85.51 ? 197 GLU C CG 1 ATOM 4412 C CD . GLU C 3 199 ? -26.397 65.127 -44.211 1.00 87.59 ? 197 GLU C CD 1 ATOM 4413 O OE1 . GLU C 3 199 ? -25.650 64.223 -44.654 1.00 84.98 ? 197 GLU C OE1 1 ATOM 4414 O OE2 . GLU C 3 199 ? -27.235 65.722 -44.922 1.00 89.77 ? 197 GLU C OE2 1 ATOM 4415 N N . ASP C 3 200 ? -26.179 64.254 -38.729 1.00 68.97 ? 198 ASP C N 1 ATOM 4416 C CA . ASP C 3 200 ? -27.191 64.267 -37.661 1.00 67.38 ? 198 ASP C CA 1 ATOM 4417 C C . ASP C 3 200 ? -26.713 64.847 -36.317 1.00 64.04 ? 198 ASP C C 1 ATOM 4418 O O . ASP C 3 200 ? -27.258 64.507 -35.263 1.00 65.12 ? 198 ASP C O 1 ATOM 4419 C CB . ASP C 3 200 ? -27.806 62.865 -37.468 1.00 67.58 ? 198 ASP C CB 1 ATOM 4420 C CG . ASP C 3 200 ? -26.773 61.735 -37.552 1.00 70.78 ? 198 ASP C CG 1 ATOM 4421 O OD1 . ASP C 3 200 ? -25.644 61.888 -37.034 1.00 70.19 ? 198 ASP C OD1 1 ATOM 4422 O OD2 . ASP C 3 200 ? -27.101 60.675 -38.132 1.00 71.40 ? 198 ASP C OD2 1 ATOM 4423 N N . THR C 3 201 ? -25.718 65.733 -36.359 1.00 60.27 ? 199 THR C N 1 ATOM 4424 C CA . THR C 3 201 ? -25.142 66.314 -35.140 1.00 60.07 ? 199 THR C CA 1 ATOM 4425 C C . THR C 3 201 ? -26.124 67.236 -34.423 1.00 58.94 ? 199 THR C C 1 ATOM 4426 O O . THR C 3 201 ? -26.740 68.097 -35.048 1.00 62.37 ? 199 THR C O 1 ATOM 4427 C CB . THR C 3 201 ? -23.842 67.099 -35.423 1.00 58.78 ? 199 THR C CB 1 ATOM 4428 O OG1 . THR C 3 201 ? -22.931 66.272 -36.153 1.00 61.57 ? 199 THR C OG1 1 ATOM 4429 C CG2 . THR C 3 201 ? -23.185 67.532 -34.126 1.00 55.57 ? 199 THR C CG2 1 ATOM 4430 N N . PHE C 3 202 ? -26.242 67.049 -33.112 1.00 55.35 ? 200 PHE C N 1 ATOM 4431 C CA . PHE C 3 202 ? -27.110 67.861 -32.264 1.00 56.47 ? 200 PHE C CA 1 ATOM 4432 C C . PHE C 3 202 ? -26.430 69.173 -31.850 1.00 55.99 ? 200 PHE C C 1 ATOM 4433 O O . PHE C 3 202 ? -25.382 69.160 -31.201 1.00 58.32 ? 200 PHE C O 1 ATOM 4434 C CB . PHE C 3 202 ? -27.516 67.031 -31.036 1.00 57.24 ? 200 PHE C CB 1 ATOM 4435 C CG . PHE C 3 202 ? -28.415 67.747 -30.057 1.00 60.01 ? 200 PHE C CG 1 ATOM 4436 C CD1 . PHE C 3 202 ? -29.472 68.552 -30.494 1.00 61.96 ? 200 PHE C CD1 1 ATOM 4437 C CD2 . PHE C 3 202 ? -28.230 67.573 -28.682 1.00 60.04 ? 200 PHE C CD2 1 ATOM 4438 C CE1 . PHE C 3 202 ? -30.309 69.199 -29.573 1.00 62.36 ? 200 PHE C CE1 1 ATOM 4439 C CE2 . PHE C 3 202 ? -29.065 68.207 -27.753 1.00 60.46 ? 200 PHE C CE2 1 ATOM 4440 C CZ . PHE C 3 202 ? -30.106 69.020 -28.200 1.00 61.59 ? 200 PHE C CZ 1 ATOM 4441 N N . PHE C 3 203 ? -27.021 70.300 -32.241 1.00 53.80 ? 201 PHE C N 1 ATOM 4442 C CA . PHE C 3 203 ? -26.548 71.619 -31.806 1.00 52.90 ? 201 PHE C CA 1 ATOM 4443 C C . PHE C 3 203 ? -27.657 72.324 -31.035 1.00 53.38 ? 201 PHE C C 1 ATOM 4444 O O . PHE C 3 203 ? -28.466 73.032 -31.627 1.00 56.54 ? 201 PHE C O 1 ATOM 4445 C CB . PHE C 3 203 ? -26.140 72.486 -32.997 1.00 51.24 ? 201 PHE C CB 1 ATOM 4446 C CG . PHE C 3 203 ? -24.830 72.107 -33.618 1.00 52.28 ? 201 PHE C CG 1 ATOM 4447 C CD1 . PHE C 3 203 ? -24.777 71.186 -34.662 1.00 53.82 ? 201 PHE C CD1 1 ATOM 4448 C CD2 . PHE C 3 203 ? -23.646 72.697 -33.187 1.00 53.81 ? 201 PHE C CD2 1 ATOM 4449 C CE1 . PHE C 3 203 ? -23.552 70.847 -35.264 1.00 55.20 ? 201 PHE C CE1 1 ATOM 4450 C CE2 . PHE C 3 203 ? -22.414 72.368 -33.782 1.00 54.89 ? 201 PHE C CE2 1 ATOM 4451 C CZ . PHE C 3 203 ? -22.371 71.441 -34.822 1.00 53.44 ? 201 PHE C CZ 1 ATOM 4452 N N . PRO C 3 204 ? -27.694 72.143 -29.708 1.00 54.70 ? 202 PRO C N 1 ATOM 4453 C CA . PRO C 3 204 ? -28.780 72.683 -28.877 1.00 56.93 ? 202 PRO C CA 1 ATOM 4454 C C . PRO C 3 204 ? -28.801 74.219 -28.777 1.00 59.57 ? 202 PRO C C 1 ATOM 4455 O O . PRO C 3 204 ? -27.749 74.841 -28.609 1.00 60.12 ? 202 PRO C O 1 ATOM 4456 C CB . PRO C 3 204 ? -28.512 72.058 -27.505 1.00 56.94 ? 202 PRO C CB 1 ATOM 4457 C CG . PRO C 3 204 ? -27.042 71.772 -27.497 1.00 57.65 ? 202 PRO C CG 1 ATOM 4458 C CD . PRO C 3 204 ? -26.674 71.436 -28.911 1.00 54.92 ? 202 PRO C CD 1 ATOM 4459 N N . SER C 3 205 ? -29.999 74.802 -28.871 1.00 63.95 ? 203 SER C N 1 ATOM 4460 C CA . SER C 3 205 ? -30.231 76.260 -28.794 1.00 65.35 ? 203 SER C CA 1 ATOM 4461 C C . SER C 3 205 ? -28.974 77.104 -28.541 1.00 67.45 ? 203 SER C C 1 ATOM 4462 O O . SER C 3 205 ? -28.667 78.029 -29.298 1.00 68.34 ? 203 SER C O 1 ATOM 4463 C CB . SER C 3 205 ? -31.278 76.576 -27.723 1.00 64.75 ? 203 SER C CB 1 ATOM 4464 O OG . SER C 3 205 ? -30.716 76.464 -26.427 1.00 63.39 ? 203 SER C OG 1 ATOM 4465 N N . ALA D 4 3 ? 5.985 41.087 -4.215 1.00 58.15 ? 2 ALA D N 1 ATOM 4466 C CA . ALA D 4 3 ? 7.384 41.598 -4.124 1.00 60.24 ? 2 ALA D CA 1 ATOM 4467 C C . ALA D 4 3 ? 7.523 42.950 -4.855 1.00 61.74 ? 2 ALA D C 1 ATOM 4468 O O . ALA D 4 3 ? 7.797 42.992 -6.062 1.00 56.03 ? 2 ALA D O 1 ATOM 4469 C CB . ALA D 4 3 ? 8.376 40.552 -4.666 1.00 57.10 ? 2 ALA D CB 1 ATOM 4470 N N . ALA D 4 4 ? 7.331 44.043 -4.103 1.00 63.20 ? 3 ALA D N 1 ATOM 4471 C CA . ALA D 4 4 ? 7.215 45.406 -4.666 1.00 58.84 ? 3 ALA D CA 1 ATOM 4472 C C . ALA D 4 4 ? 8.493 46.259 -4.612 1.00 56.21 ? 3 ALA D C 1 ATOM 4473 O O . ALA D 4 4 ? 9.346 46.091 -3.727 1.00 57.36 ? 3 ALA D O 1 ATOM 4474 C CB . ALA D 4 4 ? 6.040 46.155 -4.020 1.00 57.56 ? 3 ALA D CB 1 ATOM 4475 N N . VAL D 4 5 ? 8.598 47.181 -5.571 1.00 51.64 ? 4 VAL D N 1 ATOM 4476 C CA . VAL D 4 5 ? 9.764 48.063 -5.728 1.00 46.47 ? 4 VAL D CA 1 ATOM 4477 C C . VAL D 4 5 ? 9.305 49.484 -6.046 1.00 42.26 ? 4 VAL D C 1 ATOM 4478 O O . VAL D 4 5 ? 8.403 49.676 -6.861 1.00 41.19 ? 4 VAL D O 1 ATOM 4479 C CB . VAL D 4 5 ? 10.736 47.535 -6.829 1.00 45.80 ? 4 VAL D CB 1 ATOM 4480 C CG1 . VAL D 4 5 ? 11.797 48.562 -7.188 1.00 44.23 ? 4 VAL D CG1 1 ATOM 4481 C CG2 . VAL D 4 5 ? 11.404 46.251 -6.367 1.00 48.87 ? 4 VAL D CG2 1 ATOM 4482 N N . THR D 4 6 ? 9.928 50.468 -5.394 1.00 38.39 ? 5 THR D N 1 ATOM 4483 C CA . THR D 4 6 ? 9.542 51.870 -5.537 1.00 36.58 ? 5 THR D CA 1 ATOM 4484 C C . THR D 4 6 ? 10.718 52.749 -5.950 1.00 36.44 ? 5 THR D C 1 ATOM 4485 O O . THR D 4 6 ? 11.885 52.420 -5.682 1.00 35.99 ? 5 THR D O 1 ATOM 4486 C CB . THR D 4 6 ? 8.920 52.452 -4.233 1.00 36.17 ? 5 THR D CB 1 ATOM 4487 O OG1 . THR D 4 6 ? 9.860 52.355 -3.151 1.00 35.52 ? 5 THR D OG1 1 ATOM 4488 C CG2 . THR D 4 6 ? 7.641 51.714 -3.868 1.00 35.56 ? 5 THR D CG2 1 ATOM 4489 N N . GLN D 4 7 ? 10.382 53.873 -6.588 1.00 34.13 ? 6 GLN D N 1 ATOM 4490 C CA . GLN D 4 7 ? 11.336 54.832 -7.120 1.00 30.90 ? 6 GLN D CA 1 ATOM 4491 C C . GLN D 4 7 ? 10.882 56.215 -6.709 1.00 30.48 ? 6 GLN D C 1 ATOM 4492 O O . GLN D 4 7 ? 9.702 56.527 -6.770 1.00 29.42 ? 6 GLN D O 1 ATOM 4493 C CB . GLN D 4 7 ? 11.344 54.777 -8.650 1.00 29.94 ? 6 GLN D CB 1 ATOM 4494 C CG . GLN D 4 7 ? 11.893 53.513 -9.244 1.00 30.95 ? 6 GLN D CG 1 ATOM 4495 C CD . GLN D 4 7 ? 11.797 53.464 -10.761 1.00 31.19 ? 6 GLN D CD 1 ATOM 4496 O OE1 . GLN D 4 7 ? 11.378 52.451 -11.327 1.00 31.74 ? 6 GLN D OE1 1 ATOM 4497 N NE2 . GLN D 4 7 ? 12.203 54.545 -11.428 1.00 30.16 ? 6 GLN D NE2 1 ATOM 4498 N N . SER D 4 8 ? 11.821 57.055 -6.307 1.00 32.07 ? 7 SER D N 1 ATOM 4499 C CA . SER D 4 8 ? 11.522 58.459 -6.067 1.00 34.45 ? 7 SER D CA 1 ATOM 4500 C C . SER D 4 8 ? 12.668 59.335 -6.573 1.00 34.75 ? 7 SER D C 1 ATOM 4501 O O . SER D 4 8 ? 13.829 58.960 -6.437 1.00 35.69 ? 7 SER D O 1 ATOM 4502 C CB . SER D 4 8 ? 11.260 58.720 -4.586 1.00 35.51 ? 7 SER D CB 1 ATOM 4503 O OG . SER D 4 8 ? 12.458 58.602 -3.842 1.00 39.99 ? 7 SER D OG 1 ATOM 4504 N N . PRO D 4 9 ? 12.346 60.488 -7.182 1.00 34.64 ? 8 PRO D N 1 ATOM 4505 C CA . PRO D 4 9 ? 10.994 60.976 -7.463 1.00 34.89 ? 8 PRO D CA 1 ATOM 4506 C C . PRO D 4 9 ? 10.406 60.200 -8.618 1.00 35.23 ? 8 PRO D C 1 ATOM 4507 O O . PRO D 4 9 ? 11.115 59.422 -9.251 1.00 36.50 ? 8 PRO D O 1 ATOM 4508 C CB . PRO D 4 9 ? 11.229 62.419 -7.900 1.00 35.95 ? 8 PRO D CB 1 ATOM 4509 C CG . PRO D 4 9 ? 12.593 62.411 -8.497 1.00 36.29 ? 8 PRO D CG 1 ATOM 4510 C CD . PRO D 4 9 ? 13.383 61.385 -7.721 1.00 35.21 ? 8 PRO D CD 1 ATOM 4511 N N . ARG D 4 10 ? 9.131 60.406 -8.905 1.00 35.11 ? 9 ARG D N 1 ATOM 4512 C CA . ARG D 4 10 ? 8.522 59.719 -10.036 1.00 35.21 ? 9 ARG D CA 1 ATOM 4513 C C . ARG D 4 10 ? 8.602 60.568 -11.299 1.00 32.86 ? 9 ARG D C 1 ATOM 4514 O O . ARG D 4 10 ? 8.330 60.093 -12.398 1.00 33.74 ? 9 ARG D O 1 ATOM 4515 C CB . ARG D 4 10 ? 7.080 59.308 -9.706 1.00 38.23 ? 9 ARG D CB 1 ATOM 4516 C CG . ARG D 4 10 ? 6.974 58.205 -8.617 1.00 41.31 ? 9 ARG D CG 1 ATOM 4517 C CD . ARG D 4 10 ? 7.252 56.795 -9.167 1.00 42.18 ? 9 ARG D CD 1 ATOM 4518 N NE . ARG D 4 10 ? 6.567 56.602 -10.446 1.00 47.38 ? 9 ARG D NE 1 ATOM 4519 C CZ . ARG D 4 10 ? 5.335 56.109 -10.596 1.00 47.10 ? 9 ARG D CZ 1 ATOM 4520 N NH1 . ARG D 4 10 ? 4.629 55.711 -9.538 1.00 44.25 ? 9 ARG D NH1 1 ATOM 4521 N NH2 . ARG D 4 10 ? 4.815 56.002 -11.821 1.00 46.41 ? 9 ARG D NH2 1 ATOM 4522 N N . ASN D 4 11 ? 9.012 61.819 -11.128 1.00 30.75 ? 10 ASN D N 1 ATOM 4523 C CA . ASN D 4 11 ? 9.070 62.787 -12.209 1.00 29.12 ? 10 ASN D CA 1 ATOM 4524 C C . ASN D 4 11 ? 9.951 63.963 -11.777 1.00 28.80 ? 10 ASN D C 1 ATOM 4525 O O . ASN D 4 11 ? 9.829 64.446 -10.656 1.00 30.01 ? 10 ASN D O 1 ATOM 4526 C CB . ASN D 4 11 ? 7.653 63.248 -12.559 1.00 28.75 ? 10 ASN D CB 1 ATOM 4527 C CG . ASN D 4 11 ? 7.534 63.750 -13.986 1.00 29.96 ? 10 ASN D CG 1 ATOM 4528 O OD1 . ASN D 4 11 ? 8.259 64.646 -14.410 1.00 31.18 ? 10 ASN D OD1 1 ATOM 4529 N ND2 . ASN D 4 11 ? 6.613 63.176 -14.731 1.00 29.58 ? 10 ASN D ND2 1 ATOM 4530 N N . LYS D 4 12 ? 10.857 64.399 -12.648 1.00 28.34 ? 11 LYS D N 1 ATOM 4531 C CA . LYS D 4 12 ? 11.854 65.417 -12.298 1.00 28.44 ? 11 LYS D CA 1 ATOM 4532 C C . LYS D 4 12 ? 12.236 66.280 -13.495 1.00 29.51 ? 11 LYS D C 1 ATOM 4533 O O . LYS D 4 12 ? 12.624 65.766 -14.553 1.00 30.09 ? 11 LYS D O 1 ATOM 4534 C CB . LYS D 4 12 ? 13.116 64.768 -11.723 1.00 28.99 ? 11 LYS D CB 1 ATOM 4535 C CG . LYS D 4 12 ? 14.253 65.734 -11.363 1.00 30.43 ? 11 LYS D CG 1 ATOM 4536 C CD . LYS D 4 12 ? 14.123 66.257 -9.942 1.00 31.70 ? 11 LYS D CD 1 ATOM 4537 C CE . LYS D 4 12 ? 15.090 67.386 -9.643 1.00 32.62 ? 11 LYS D CE 1 ATOM 4538 N NZ . LYS D 4 12 ? 14.754 68.012 -8.315 1.00 34.20 ? 11 LYS D NZ 1 ATOM 4539 N N . VAL D 4 13 ? 12.115 67.592 -13.309 1.00 29.35 ? 12 VAL D N 1 ATOM 4540 C CA . VAL D 4 13 ? 12.582 68.576 -14.272 1.00 29.37 ? 12 VAL D CA 1 ATOM 4541 C C . VAL D 4 13 ? 13.821 69.212 -13.669 1.00 29.53 ? 12 VAL D C 1 ATOM 4542 O O . VAL D 4 13 ? 13.813 69.609 -12.510 1.00 31.26 ? 12 VAL D O 1 ATOM 4543 C CB . VAL D 4 13 ? 11.499 69.653 -14.575 1.00 29.52 ? 12 VAL D CB 1 ATOM 4544 C CG1 . VAL D 4 13 ? 12.020 70.695 -15.567 1.00 27.97 ? 12 VAL D CG1 1 ATOM 4545 C CG2 . VAL D 4 13 ? 10.228 68.999 -15.109 1.00 27.66 ? 12 VAL D CG2 1 ATOM 4546 N N . ALA D 4 14 ? 14.888 69.280 -14.458 1.00 30.75 ? 13 ALA D N 1 ATOM 4547 C CA . ALA D 4 14 ? 16.220 69.652 -13.974 1.00 29.93 ? 13 ALA D CA 1 ATOM 4548 C C . ALA D 4 14 ? 16.972 70.498 -14.995 1.00 29.68 ? 13 ALA D C 1 ATOM 4549 O O . ALA D 4 14 ? 16.667 70.451 -16.190 1.00 29.90 ? 13 ALA D O 1 ATOM 4550 C CB . ALA D 4 14 ? 17.016 68.397 -13.648 1.00 28.92 ? 13 ALA D CB 1 ATOM 4551 N N . VAL D 4 15 ? 17.952 71.266 -14.518 1.00 29.99 ? 14 VAL D N 1 ATOM 4552 C CA . VAL D 4 15 ? 18.812 72.084 -15.391 1.00 29.49 ? 14 VAL D CA 1 ATOM 4553 C C . VAL D 4 15 ? 20.129 71.376 -15.680 1.00 29.60 ? 14 VAL D C 1 ATOM 4554 O O . VAL D 4 15 ? 20.577 70.535 -14.885 1.00 29.40 ? 14 VAL D O 1 ATOM 4555 C CB . VAL D 4 15 ? 19.082 73.525 -14.794 1.00 28.67 ? 14 VAL D CB 1 ATOM 4556 C CG1 . VAL D 4 15 ? 20.091 73.507 -13.641 1.00 26.80 ? 14 VAL D CG1 1 ATOM 4557 C CG2 . VAL D 4 15 ? 19.549 74.486 -15.881 1.00 28.83 ? 14 VAL D CG2 1 ATOM 4558 N N . THR D 4 16 ? 20.747 71.730 -16.808 1.00 29.81 ? 15 THR D N 1 ATOM 4559 C CA . THR D 4 16 ? 22.103 71.280 -17.141 1.00 30.42 ? 15 THR D CA 1 ATOM 4560 C C . THR D 4 16 ? 23.107 71.671 -16.067 1.00 29.76 ? 15 THR D C 1 ATOM 4561 O O . THR D 4 16 ? 23.040 72.770 -15.518 1.00 30.07 ? 15 THR D O 1 ATOM 4562 C CB . THR D 4 16 ? 22.569 71.862 -18.478 1.00 30.89 ? 15 THR D CB 1 ATOM 4563 O OG1 . THR D 4 16 ? 21.704 71.395 -19.517 1.00 32.08 ? 15 THR D OG1 1 ATOM 4564 C CG2 . THR D 4 16 ? 24.005 71.439 -18.789 1.00 31.08 ? 15 THR D CG2 1 ATOM 4565 N N . GLY D 4 17 ? 24.032 70.762 -15.775 1.00 29.62 ? 16 GLY D N 1 ATOM 4566 C CA . GLY D 4 17 ? 25.064 71.002 -14.777 1.00 29.45 ? 16 GLY D CA 1 ATOM 4567 C C . GLY D 4 17 ? 24.581 70.729 -13.366 1.00 30.68 ? 16 GLY D C 1 ATOM 4568 O O . GLY D 4 17 ? 25.371 70.733 -12.424 1.00 30.64 ? 16 GLY D O 1 ATOM 4569 N N . GLY D 4 18 ? 23.279 70.487 -13.216 1.00 32.05 ? 17 GLY D N 1 ATOM 4570 C CA . GLY D 4 18 ? 22.697 70.184 -11.911 1.00 33.37 ? 17 GLY D CA 1 ATOM 4571 C C . GLY D 4 18 ? 22.990 68.754 -11.477 1.00 34.91 ? 17 GLY D C 1 ATOM 4572 O O . GLY D 4 18 ? 23.368 67.910 -12.295 1.00 34.22 ? 17 GLY D O 1 ATOM 4573 N N . LYS D 4 19 ? 22.843 68.492 -10.181 1.00 36.11 ? 18 LYS D N 1 ATOM 4574 C CA . LYS D 4 19 ? 22.966 67.146 -9.646 1.00 36.27 ? 18 LYS D CA 1 ATOM 4575 C C . LYS D 4 19 ? 21.574 66.582 -9.549 1.00 35.59 ? 18 LYS D C 1 ATOM 4576 O O . LYS D 4 19 ? 20.698 67.197 -8.950 1.00 35.50 ? 18 LYS D O 1 ATOM 4577 C CB . LYS D 4 19 ? 23.581 67.160 -8.252 1.00 37.86 ? 18 LYS D CB 1 ATOM 4578 C CG . LYS D 4 19 ? 23.789 65.769 -7.654 1.00 40.68 ? 18 LYS D CG 1 ATOM 4579 C CD . LYS D 4 19 ? 24.070 65.833 -6.165 1.00 41.74 ? 18 LYS D CD 1 ATOM 4580 C CE . LYS D 4 19 ? 25.246 64.951 -5.806 1.00 41.29 ? 18 LYS D CE 1 ATOM 4581 N NZ . LYS D 4 19 ? 25.668 65.182 -4.386 1.00 43.34 ? 18 LYS D NZ 1 ATOM 4582 N N . VAL D 4 20 ? 21.363 65.418 -10.147 1.00 34.56 ? 19 VAL D N 1 ATOM 4583 C CA . VAL D 4 20 ? 20.116 64.703 -9.950 1.00 34.43 ? 19 VAL D CA 1 ATOM 4584 C C . VAL D 4 20 ? 20.393 63.368 -9.256 1.00 35.32 ? 19 VAL D C 1 ATOM 4585 O O . VAL D 4 20 ? 21.356 62.666 -9.591 1.00 37.00 ? 19 VAL D O 1 ATOM 4586 C CB . VAL D 4 20 ? 19.370 64.471 -11.270 1.00 33.26 ? 19 VAL D CB 1 ATOM 4587 C CG1 . VAL D 4 20 ? 18.086 63.697 -11.018 1.00 32.56 ? 19 VAL D CG1 1 ATOM 4588 C CG2 . VAL D 4 20 ? 19.068 65.790 -11.935 1.00 32.11 ? 19 VAL D CG2 1 ATOM 4589 N N . THR D 4 21 ? 19.555 63.027 -8.286 1.00 32.84 ? 20 THR D N 1 ATOM 4590 C CA . THR D 4 21 ? 19.655 61.740 -7.645 1.00 32.73 ? 20 THR D CA 1 ATOM 4591 C C . THR D 4 21 ? 18.367 60.960 -7.854 1.00 32.89 ? 20 THR D C 1 ATOM 4592 O O . THR D 4 21 ? 17.272 61.424 -7.500 1.00 33.21 ? 20 THR D O 1 ATOM 4593 C CB . THR D 4 21 ? 19.967 61.881 -6.155 1.00 33.45 ? 20 THR D CB 1 ATOM 4594 O OG1 . THR D 4 21 ? 21.145 62.682 -6.002 1.00 35.03 ? 20 THR D OG1 1 ATOM 4595 C CG2 . THR D 4 21 ? 20.188 60.510 -5.518 1.00 32.72 ? 20 THR D CG2 1 ATOM 4596 N N . LEU D 4 22 ? 18.509 59.777 -8.442 1.00 31.38 ? 21 LEU D N 1 ATOM 4597 C CA . LEU D 4 22 ? 17.380 58.892 -8.647 1.00 31.20 ? 21 LEU D CA 1 ATOM 4598 C C . LEU D 4 22 ? 17.453 57.766 -7.635 1.00 32.31 ? 21 LEU D C 1 ATOM 4599 O O . LEU D 4 22 ? 18.501 57.159 -7.459 1.00 33.69 ? 21 LEU D O 1 ATOM 4600 C CB . LEU D 4 22 ? 17.375 58.367 -10.083 1.00 29.85 ? 21 LEU D CB 1 ATOM 4601 C CG . LEU D 4 22 ? 17.076 59.428 -11.146 1.00 28.13 ? 21 LEU D CG 1 ATOM 4602 C CD1 . LEU D 4 22 ? 16.694 58.795 -12.459 1.00 27.73 ? 21 LEU D CD1 1 ATOM 4603 C CD2 . LEU D 4 22 ? 15.971 60.354 -10.680 1.00 27.29 ? 21 LEU D CD2 1 ATOM 4604 N N . SER D 4 23 ? 16.352 57.499 -6.949 1.00 34.10 ? 22 SER D N 1 ATOM 4605 C CA . SER D 4 23 ? 16.381 56.517 -5.869 1.00 36.14 ? 22 SER D CA 1 ATOM 4606 C C . SER D 4 23 ? 15.467 55.326 -6.069 1.00 36.42 ? 22 SER D C 1 ATOM 4607 O O . SER D 4 23 ? 14.402 55.432 -6.685 1.00 35.99 ? 22 SER D O 1 ATOM 4608 C CB . SER D 4 23 ? 16.078 57.182 -4.531 1.00 37.26 ? 22 SER D CB 1 ATOM 4609 O OG . SER D 4 23 ? 17.229 57.869 -4.084 1.00 42.56 ? 22 SER D OG 1 ATOM 4610 N N . CYS D 4 24 ? 15.899 54.196 -5.518 1.00 36.32 ? 23 CYS D N 1 ATOM 4611 C CA . CYS D 4 24 ? 15.130 52.974 -5.562 1.00 36.96 ? 23 CYS D CA 1 ATOM 4612 C C . CYS D 4 24 ? 15.148 52.291 -4.219 1.00 36.10 ? 23 CYS D C 1 ATOM 4613 O O . CYS D 4 24 ? 16.222 52.063 -3.651 1.00 35.39 ? 23 CYS D O 1 ATOM 4614 C CB . CYS D 4 24 ? 15.737 52.041 -6.584 1.00 39.76 ? 23 CYS D CB 1 ATOM 4615 S SG . CYS D 4 24 ? 14.754 50.615 -6.961 1.00 40.98 ? 23 CYS D SG 1 ATOM 4616 N N . ASN D 4 25 ? 13.955 51.966 -3.727 1.00 36.00 ? 24 ASN D N 1 ATOM 4617 C CA . ASN D 4 25 ? 13.792 51.216 -2.484 1.00 37.08 ? 24 ASN D CA 1 ATOM 4618 C C . ASN D 4 25 ? 12.987 49.937 -2.668 1.00 37.52 ? 24 ASN D C 1 ATOM 4619 O O . ASN D 4 25 ? 11.921 49.935 -3.304 1.00 36.44 ? 24 ASN D O 1 ATOM 4620 C CB . ASN D 4 25 ? 13.176 52.064 -1.362 1.00 37.97 ? 24 ASN D CB 1 ATOM 4621 C CG . ASN D 4 25 ? 13.164 51.329 -0.017 1.00 39.09 ? 24 ASN D CG 1 ATOM 4622 O OD1 . ASN D 4 25 ? 14.188 51.262 0.675 1.00 40.84 ? 24 ASN D OD1 1 ATOM 4623 N ND2 . ASN D 4 25 ? 12.012 50.758 0.346 1.00 37.67 ? 24 ASN D ND2 1 ATOM 4624 N N . GLN D 4 26 ? 13.510 48.870 -2.063 1.00 38.23 ? 25 GLN D N 1 ATOM 4625 C CA . GLN D 4 26 ? 13.045 47.503 -2.256 1.00 39.36 ? 25 GLN D CA 1 ATOM 4626 C C . GLN D 4 26 ? 13.145 46.736 -0.928 1.00 40.63 ? 25 GLN D C 1 ATOM 4627 O O . GLN D 4 26 ? 14.229 46.627 -0.338 1.00 42.79 ? 25 GLN D O 1 ATOM 4628 C CB . GLN D 4 26 ? 13.889 46.854 -3.359 1.00 37.39 ? 25 GLN D CB 1 ATOM 4629 C CG . GLN D 4 26 ? 14.001 45.347 -3.321 1.00 37.27 ? 25 GLN D CG 1 ATOM 4630 C CD . GLN D 4 26 ? 15.211 44.848 -2.550 1.00 35.31 ? 25 GLN D CD 1 ATOM 4631 O OE1 . GLN D 4 26 ? 16.267 45.476 -2.522 1.00 32.93 ? 25 GLN D OE1 1 ATOM 4632 N NE2 . GLN D 4 26 ? 15.050 43.703 -1.918 1.00 36.15 ? 25 GLN D NE2 1 ATOM 4633 N N . THR D 4 27 ? 12.021 46.206 -0.460 1.00 40.91 ? 26 THR D N 1 ATOM 4634 C CA . THR D 4 27 ? 11.976 45.605 0.882 1.00 41.92 ? 26 THR D CA 1 ATOM 4635 C C . THR D 4 27 ? 11.958 44.075 0.876 1.00 42.89 ? 26 THR D C 1 ATOM 4636 O O . THR D 4 27 ? 11.539 43.458 1.860 1.00 44.61 ? 26 THR D O 1 ATOM 4637 C CB . THR D 4 27 ? 10.764 46.138 1.717 1.00 40.91 ? 26 THR D CB 1 ATOM 4638 O OG1 . THR D 4 27 ? 9.586 46.192 0.896 1.00 40.76 ? 26 THR D OG1 1 ATOM 4639 C CG2 . THR D 4 27 ? 11.055 47.520 2.277 1.00 37.98 ? 26 THR D CG2 1 ATOM 4640 N N . ASN D 4 28 ? 12.424 43.472 -0.220 1.00 41.56 ? 27 ASN D N 1 ATOM 4641 C CA . ASN D 4 28 ? 12.276 42.026 -0.449 1.00 40.08 ? 27 ASN D CA 1 ATOM 4642 C C . ASN D 4 28 ? 13.529 41.242 -0.083 1.00 38.79 ? 27 ASN D C 1 ATOM 4643 O O . ASN D 4 28 ? 13.637 40.046 -0.358 1.00 36.25 ? 27 ASN D O 1 ATOM 4644 C CB . ASN D 4 28 ? 11.914 41.746 -1.913 1.00 39.98 ? 27 ASN D CB 1 ATOM 4645 C CG . ASN D 4 28 ? 10.685 42.492 -2.367 1.00 40.90 ? 27 ASN D CG 1 ATOM 4646 O OD1 . ASN D 4 28 ? 9.656 42.458 -1.699 1.00 42.06 ? 27 ASN D OD1 1 ATOM 4647 N ND2 . ASN D 4 28 ? 10.779 43.171 -3.519 1.00 40.66 ? 27 ASN D ND2 1 ATOM 4648 N N . ASN D 4 29 ? 14.479 41.935 0.529 1.00 39.08 ? 28 ASN D N 1 ATOM 4649 C CA . ASN D 4 29 ? 15.774 41.352 0.873 1.00 41.82 ? 28 ASN D CA 1 ATOM 4650 C C . ASN D 4 29 ? 16.510 40.712 -0.326 1.00 40.17 ? 28 ASN D C 1 ATOM 4651 O O . ASN D 4 29 ? 17.272 39.754 -0.168 1.00 40.05 ? 28 ASN D O 1 ATOM 4652 C CB . ASN D 4 29 ? 15.648 40.374 2.057 1.00 41.95 ? 28 ASN D CB 1 ATOM 4653 C CG . ASN D 4 29 ? 16.948 40.222 2.819 1.00 44.19 ? 28 ASN D CG 1 ATOM 4654 O OD1 . ASN D 4 29 ? 17.853 41.059 2.703 1.00 46.60 ? 28 ASN D OD1 1 ATOM 4655 N ND2 . ASN D 4 29 ? 17.058 39.150 3.596 1.00 44.81 ? 28 ASN D ND2 1 ATOM 4656 N N . HIS D 4 30 ? 16.262 41.263 -1.515 1.00 37.95 ? 29 HIS D N 1 ATOM 4657 C CA . HIS D 4 30 ? 16.937 40.876 -2.754 1.00 36.01 ? 29 HIS D CA 1 ATOM 4658 C C . HIS D 4 30 ? 18.325 41.423 -2.763 1.00 34.83 ? 29 HIS D C 1 ATOM 4659 O O . HIS D 4 30 ? 18.523 42.611 -2.519 1.00 36.13 ? 29 HIS D O 1 ATOM 4660 C CB . HIS D 4 30 ? 16.176 41.443 -3.938 1.00 35.06 ? 29 HIS D CB 1 ATOM 4661 C CG . HIS D 4 30 ? 14.864 40.753 -4.213 1.00 34.32 ? 29 HIS D CG 1 ATOM 4662 N ND1 . HIS D 4 30 ? 14.097 41.064 -5.272 1.00 34.51 ? 29 HIS D ND1 1 ATOM 4663 C CD2 . HIS D 4 30 ? 14.211 39.726 -3.546 1.00 34.39 ? 29 HIS D CD2 1 ATOM 4664 C CE1 . HIS D 4 30 ? 13.003 40.285 -5.281 1.00 34.84 ? 29 HIS D CE1 1 ATOM 4665 N NE2 . HIS D 4 30 ? 13.073 39.464 -4.226 1.00 35.31 ? 29 HIS D NE2 1 ATOM 4666 N N . ASN D 4 31 ? 19.303 40.564 -3.036 1.00 34.27 ? 30 ASN D N 1 ATOM 4667 C CA . ASN D 4 31 ? 20.708 40.993 -3.106 1.00 33.29 ? 30 ASN D CA 1 ATOM 4668 C C . ASN D 4 31 ? 20.991 41.946 -4.271 1.00 30.67 ? 30 ASN D C 1 ATOM 4669 O O . ASN D 4 31 ? 21.935 42.727 -4.217 1.00 30.12 ? 30 ASN D O 1 ATOM 4670 C CB . ASN D 4 31 ? 21.659 39.777 -3.212 1.00 34.30 ? 30 ASN D CB 1 ATOM 4671 C CG . ASN D 4 31 ? 22.069 39.199 -1.850 1.00 34.58 ? 30 ASN D CG 1 ATOM 4672 O OD1 . ASN D 4 31 ? 21.463 39.488 -0.817 1.00 35.01 ? 30 ASN D OD1 1 ATOM 4673 N ND2 . ASN D 4 31 ? 23.109 38.373 -1.856 1.00 33.27 ? 30 ASN D ND2 1 ATOM 4674 N N . ASN D 4 32 ? 20.167 41.873 -5.316 1.00 28.46 ? 31 ASN D N 1 ATOM 4675 C CA . ASN D 4 32 ? 20.528 42.425 -6.619 1.00 27.02 ? 31 ASN D CA 1 ATOM 4676 C C . ASN D 4 32 ? 19.610 43.513 -7.111 1.00 27.01 ? 31 ASN D C 1 ATOM 4677 O O . ASN D 4 32 ? 18.384 43.353 -7.118 1.00 26.41 ? 31 ASN D O 1 ATOM 4678 C CB . ASN D 4 32 ? 20.575 41.308 -7.659 1.00 26.35 ? 31 ASN D CB 1 ATOM 4679 C CG . ASN D 4 32 ? 21.294 40.088 -7.155 1.00 26.11 ? 31 ASN D CG 1 ATOM 4680 O OD1 . ASN D 4 32 ? 22.460 40.166 -6.758 1.00 27.10 ? 31 ASN D OD1 1 ATOM 4681 N ND2 . ASN D 4 32 ? 20.607 38.955 -7.144 1.00 25.09 ? 31 ASN D ND2 1 ATOM 4682 N N . MET D 4 33 ? 20.208 44.619 -7.545 1.00 26.89 ? 32 MET D N 1 ATOM 4683 C CA . MET D 4 33 ? 19.426 45.737 -8.064 1.00 27.31 ? 32 MET D CA 1 ATOM 4684 C C . MET D 4 33 ? 20.045 46.301 -9.341 1.00 27.38 ? 32 MET D C 1 ATOM 4685 O O . MET D 4 33 ? 21.261 46.229 -9.546 1.00 28.55 ? 32 MET D O 1 ATOM 4686 C CB . MET D 4 33 ? 19.228 46.815 -7.001 1.00 27.37 ? 32 MET D CB 1 ATOM 4687 C CG . MET D 4 33 ? 18.741 46.261 -5.665 1.00 28.33 ? 32 MET D CG 1 ATOM 4688 S SD . MET D 4 33 ? 18.320 47.512 -4.450 1.00 29.35 ? 32 MET D SD 1 ATOM 4689 C CE . MET D 4 33 ? 16.826 48.177 -5.192 1.00 27.98 ? 32 MET D CE 1 ATOM 4690 N N . TYR D 4 34 ? 19.189 46.845 -10.195 1.00 25.60 ? 33 TYR D N 1 ATOM 4691 C CA . TYR D 4 34 ? 19.562 47.175 -11.544 1.00 25.67 ? 33 TYR D CA 1 ATOM 4692 C C . TYR D 4 34 ? 18.892 48.479 -11.931 1.00 26.42 ? 33 TYR D C 1 ATOM 4693 O O . TYR D 4 34 ? 17.763 48.760 -11.492 1.00 27.82 ? 33 TYR D O 1 ATOM 4694 C CB . TYR D 4 34 ? 19.072 46.078 -12.500 1.00 26.26 ? 33 TYR D CB 1 ATOM 4695 C CG . TYR D 4 34 ? 19.468 44.674 -12.111 1.00 25.14 ? 33 TYR D CG 1 ATOM 4696 C CD1 . TYR D 4 34 ? 20.653 44.111 -12.593 1.00 24.33 ? 33 TYR D CD1 1 ATOM 4697 C CD2 . TYR D 4 34 ? 18.658 43.905 -11.265 1.00 24.49 ? 33 TYR D CD2 1 ATOM 4698 C CE1 . TYR D 4 34 ? 21.030 42.828 -12.242 1.00 24.23 ? 33 TYR D CE1 1 ATOM 4699 C CE2 . TYR D 4 34 ? 19.029 42.610 -10.899 1.00 24.08 ? 33 TYR D CE2 1 ATOM 4700 C CZ . TYR D 4 34 ? 20.215 42.081 -11.393 1.00 23.95 ? 33 TYR D CZ 1 ATOM 4701 O OH . TYR D 4 34 ? 20.594 40.812 -11.053 1.00 23.60 ? 33 TYR D OH 1 ATOM 4702 N N . TRP D 4 35 ? 19.583 49.256 -12.766 1.00 24.59 ? 34 TRP D N 1 ATOM 4703 C CA . TRP D 4 35 ? 19.079 50.523 -13.260 1.00 23.36 ? 34 TRP D CA 1 ATOM 4704 C C . TRP D 4 35 ? 19.097 50.530 -14.749 1.00 23.36 ? 34 TRP D C 1 ATOM 4705 O O . TRP D 4 35 ? 20.146 50.283 -15.368 1.00 23.74 ? 34 TRP D O 1 ATOM 4706 C CB . TRP D 4 35 ? 19.954 51.669 -12.772 1.00 23.17 ? 34 TRP D CB 1 ATOM 4707 C CG . TRP D 4 35 ? 19.490 52.339 -11.506 1.00 22.02 ? 34 TRP D CG 1 ATOM 4708 C CD1 . TRP D 4 35 ? 20.172 52.428 -10.301 1.00 22.10 ? 34 TRP D CD1 1 ATOM 4709 C CD2 . TRP D 4 35 ? 18.238 53.061 -11.288 1.00 21.71 ? 34 TRP D CD2 1 ATOM 4710 N NE1 . TRP D 4 35 ? 19.445 53.126 -9.374 1.00 21.81 ? 34 TRP D NE1 1 ATOM 4711 C CE2 . TRP D 4 35 ? 18.270 53.525 -9.899 1.00 22.10 ? 34 TRP D CE2 1 ATOM 4712 C CE3 . TRP D 4 35 ? 17.129 53.348 -12.067 1.00 21.71 ? 34 TRP D CE3 1 ATOM 4713 C CZ2 . TRP D 4 35 ? 17.223 54.245 -9.341 1.00 22.13 ? 34 TRP D CZ2 1 ATOM 4714 C CZ3 . TRP D 4 35 ? 16.078 54.071 -11.498 1.00 21.23 ? 34 TRP D CZ3 1 ATOM 4715 C CH2 . TRP D 4 35 ? 16.127 54.512 -10.171 1.00 21.66 ? 34 TRP D CH2 1 ATOM 4716 N N . TYR D 4 36 ? 17.947 50.831 -15.338 1.00 22.33 ? 35 TYR D N 1 ATOM 4717 C CA . TYR D 4 36 ? 17.824 50.960 -16.789 1.00 22.69 ? 35 TYR D CA 1 ATOM 4718 C C . TYR D 4 36 ? 17.281 52.339 -17.206 1.00 22.80 ? 35 TYR D C 1 ATOM 4719 O O . TYR D 4 36 ? 16.629 53.021 -16.415 1.00 22.60 ? 35 TYR D O 1 ATOM 4720 C CB . TYR D 4 36 ? 16.850 49.913 -17.323 1.00 23.16 ? 35 TYR D CB 1 ATOM 4721 C CG . TYR D 4 36 ? 17.188 48.477 -17.049 1.00 23.30 ? 35 TYR D CG 1 ATOM 4722 C CD1 . TYR D 4 36 ? 16.784 47.859 -15.872 1.00 23.51 ? 35 TYR D CD1 1 ATOM 4723 C CD2 . TYR D 4 36 ? 17.878 47.714 -18.001 1.00 24.30 ? 35 TYR D CD2 1 ATOM 4724 C CE1 . TYR D 4 36 ? 17.086 46.513 -15.634 1.00 24.68 ? 35 TYR D CE1 1 ATOM 4725 C CE2 . TYR D 4 36 ? 18.178 46.368 -17.782 1.00 23.72 ? 35 TYR D CE2 1 ATOM 4726 C CZ . TYR D 4 36 ? 17.782 45.780 -16.603 1.00 24.52 ? 35 TYR D CZ 1 ATOM 4727 O OH . TYR D 4 36 ? 18.080 44.464 -16.386 1.00 25.27 ? 35 TYR D OH 1 ATOM 4728 N N . ARG D 4 37 ? 17.532 52.739 -18.452 1.00 23.30 ? 36 ARG D N 1 ATOM 4729 C CA . ARG D 4 37 ? 16.782 53.852 -19.064 1.00 23.57 ? 36 ARG D CA 1 ATOM 4730 C C . ARG D 4 37 ? 16.106 53.360 -20.328 1.00 24.14 ? 36 ARG D C 1 ATOM 4731 O O . ARG D 4 37 ? 16.638 52.477 -21.002 1.00 23.83 ? 36 ARG D O 1 ATOM 4732 C CB . ARG D 4 37 ? 17.665 55.065 -19.365 1.00 23.44 ? 36 ARG D CB 1 ATOM 4733 C CG . ARG D 4 37 ? 18.833 54.806 -20.320 1.00 23.14 ? 36 ARG D CG 1 ATOM 4734 C CD . ARG D 4 37 ? 19.643 56.084 -20.562 1.00 23.30 ? 36 ARG D CD 1 ATOM 4735 N NE . ARG D 4 37 ? 18.965 57.024 -21.460 1.00 23.27 ? 36 ARG D NE 1 ATOM 4736 C CZ . ARG D 4 37 ? 19.377 58.269 -21.702 1.00 23.46 ? 36 ARG D CZ 1 ATOM 4737 N NH1 . ARG D 4 37 ? 20.468 58.761 -21.118 1.00 22.13 ? 36 ARG D NH1 1 ATOM 4738 N NH2 . ARG D 4 37 ? 18.686 59.033 -22.531 1.00 23.57 ? 36 ARG D NH2 1 ATOM 4739 N N . GLN D 4 38 ? 14.927 53.918 -20.618 1.00 25.18 ? 37 GLN D N 1 ATOM 4740 C CA . GLN D 4 38 ? 14.135 53.584 -21.803 1.00 25.59 ? 37 GLN D CA 1 ATOM 4741 C C . GLN D 4 38 ? 13.989 54.813 -22.679 1.00 27.82 ? 37 GLN D C 1 ATOM 4742 O O . GLN D 4 38 ? 13.483 55.848 -22.239 1.00 26.94 ? 37 GLN D O 1 ATOM 4743 C CB . GLN D 4 38 ? 12.760 53.073 -21.403 1.00 24.21 ? 37 GLN D CB 1 ATOM 4744 C CG . GLN D 4 38 ? 11.810 52.760 -22.566 1.00 23.69 ? 37 GLN D CG 1 ATOM 4745 C CD . GLN D 4 38 ? 10.432 52.270 -22.083 1.00 23.30 ? 37 GLN D CD 1 ATOM 4746 O OE1 . GLN D 4 38 ? 9.759 52.939 -21.289 1.00 22.60 ? 37 GLN D OE1 1 ATOM 4747 N NE2 . GLN D 4 38 ? 10.021 51.088 -22.550 1.00 22.91 ? 37 GLN D NE2 1 ATOM 4748 N N . ASP D 4 39 ? 14.464 54.683 -23.915 1.00 32.21 ? 38 ASP D N 1 ATOM 4749 C CA . ASP D 4 39 ? 14.368 55.727 -24.930 1.00 35.59 ? 38 ASP D CA 1 ATOM 4750 C C . ASP D 4 39 ? 13.610 55.176 -26.121 1.00 37.62 ? 38 ASP D C 1 ATOM 4751 O O . ASP D 4 39 ? 13.899 54.071 -26.599 1.00 38.04 ? 38 ASP D O 1 ATOM 4752 C CB . ASP D 4 39 ? 15.761 56.208 -25.335 1.00 36.73 ? 38 ASP D CB 1 ATOM 4753 C CG . ASP D 4 39 ? 16.561 56.696 -24.145 1.00 39.08 ? 38 ASP D CG 1 ATOM 4754 O OD1 . ASP D 4 39 ? 16.022 57.541 -23.402 1.00 37.90 ? 38 ASP D OD1 1 ATOM 4755 O OD2 . ASP D 4 39 ? 17.706 56.226 -23.935 1.00 41.19 ? 38 ASP D OD2 1 ATOM 4756 N N . THR D 4 40 ? 12.624 55.938 -26.585 1.00 39.39 ? 39 THR D N 1 ATOM 4757 C CA . THR D 4 40 ? 11.747 55.455 -27.645 1.00 41.71 ? 39 THR D CA 1 ATOM 4758 C C . THR D 4 40 ? 12.581 55.043 -28.858 1.00 42.70 ? 39 THR D C 1 ATOM 4759 O O . THR D 4 40 ? 13.451 55.788 -29.307 1.00 41.91 ? 39 THR D O 1 ATOM 4760 C CB . THR D 4 40 ? 10.662 56.477 -28.009 1.00 42.39 ? 39 THR D CB 1 ATOM 4761 O OG1 . THR D 4 40 ? 11.271 57.757 -28.177 1.00 44.46 ? 39 THR D OG1 1 ATOM 4762 C CG2 . THR D 4 40 ? 9.588 56.556 -26.892 1.00 40.26 ? 39 THR D CG2 1 ATOM 4763 N N . GLY D 4 41 ? 12.347 53.823 -29.336 1.00 43.39 ? 40 GLY D N 1 ATOM 4764 C CA . GLY D 4 41 ? 13.125 53.272 -30.437 1.00 42.86 ? 40 GLY D CA 1 ATOM 4765 C C . GLY D 4 41 ? 14.289 52.408 -29.983 1.00 43.53 ? 40 GLY D C 1 ATOM 4766 O O . GLY D 4 41 ? 15.056 51.901 -30.819 1.00 42.30 ? 40 GLY D O 1 ATOM 4767 N N . HIS D 4 42 ? 14.430 52.257 -28.662 1.00 41.91 ? 41 HIS D N 1 ATOM 4768 C CA . HIS D 4 42 ? 15.354 51.281 -28.071 1.00 39.77 ? 41 HIS D CA 1 ATOM 4769 C C . HIS D 4 42 ? 14.649 50.475 -27.038 1.00 35.43 ? 41 HIS D C 1 ATOM 4770 O O . HIS D 4 42 ? 13.595 50.863 -26.551 1.00 35.83 ? 41 HIS D O 1 ATOM 4771 C CB . HIS D 4 42 ? 16.558 51.971 -27.446 1.00 45.03 ? 41 HIS D CB 1 ATOM 4772 C CG . HIS D 4 42 ? 17.384 52.750 -28.434 1.00 51.35 ? 41 HIS D CG 1 ATOM 4773 N ND1 . HIS D 4 42 ? 16.998 53.958 -28.911 1.00 52.96 ? 41 HIS D ND1 1 ATOM 4774 C CD2 . HIS D 4 42 ? 18.595 52.448 -29.052 1.00 51.73 ? 41 HIS D CD2 1 ATOM 4775 C CE1 . HIS D 4 42 ? 17.919 54.405 -29.782 1.00 53.41 ? 41 HIS D CE1 1 ATOM 4776 N NE2 . HIS D 4 42 ? 18.895 53.479 -29.867 1.00 54.34 ? 41 HIS D NE2 1 ATOM 4777 N N . GLY D 4 43 ? 15.214 49.331 -26.692 1.00 32.79 ? 42 GLY D N 1 ATOM 4778 C CA . GLY D 4 43 ? 14.734 48.600 -25.533 1.00 31.78 ? 42 GLY D CA 1 ATOM 4779 C C . GLY D 4 43 ? 15.318 49.255 -24.296 1.00 30.90 ? 42 GLY D C 1 ATOM 4780 O O . GLY D 4 43 ? 16.101 50.211 -24.397 1.00 32.17 ? 42 GLY D O 1 ATOM 4781 N N . LEU D 4 44 ? 14.925 48.772 -23.124 1.00 28.11 ? 43 LEU D N 1 ATOM 4782 C CA . LEU D 4 44 ? 15.620 49.150 -21.901 1.00 27.11 ? 43 LEU D CA 1 ATOM 4783 C C . LEU D 4 44 ? 17.126 48.864 -22.017 1.00 26.12 ? 43 LEU D C 1 ATOM 4784 O O . LEU D 4 44 ? 17.516 47.850 -22.583 1.00 26.25 ? 43 LEU D O 1 ATOM 4785 C CB . LEU D 4 44 ? 15.022 48.420 -20.701 1.00 26.12 ? 43 LEU D CB 1 ATOM 4786 C CG . LEU D 4 44 ? 13.940 49.148 -19.909 1.00 25.71 ? 43 LEU D CG 1 ATOM 4787 C CD1 . LEU D 4 44 ? 12.686 49.413 -20.749 1.00 24.69 ? 43 LEU D CD1 1 ATOM 4788 C CD2 . LEU D 4 44 ? 13.606 48.330 -18.652 1.00 25.07 ? 43 LEU D CD2 1 ATOM 4789 N N . ARG D 4 45 ? 17.959 49.774 -21.512 1.00 25.15 ? 44 ARG D N 1 ATOM 4790 C CA . ARG D 4 45 ? 19.411 49.569 -21.495 1.00 25.24 ? 44 ARG D CA 1 ATOM 4791 C C . ARG D 4 45 ? 20.040 49.672 -20.101 1.00 24.24 ? 44 ARG D C 1 ATOM 4792 O O . ARG D 4 45 ? 19.728 50.576 -19.319 1.00 23.47 ? 44 ARG D O 1 ATOM 4793 C CB . ARG D 4 45 ? 20.109 50.506 -22.469 1.00 25.96 ? 44 ARG D CB 1 ATOM 4794 C CG . ARG D 4 45 ? 20.088 49.993 -23.888 1.00 29.83 ? 44 ARG D CG 1 ATOM 4795 C CD . ARG D 4 45 ? 20.678 51.001 -24.862 1.00 32.38 ? 44 ARG D CD 1 ATOM 4796 N NE . ARG D 4 45 ? 20.074 52.324 -24.704 1.00 35.17 ? 44 ARG D NE 1 ATOM 4797 C CZ . ARG D 4 45 ? 20.506 53.414 -25.327 1.00 36.15 ? 44 ARG D CZ 1 ATOM 4798 N NH1 . ARG D 4 45 ? 21.544 53.327 -26.155 1.00 37.74 ? 44 ARG D NH1 1 ATOM 4799 N NH2 . ARG D 4 45 ? 19.907 54.581 -25.124 1.00 34.82 ? 44 ARG D NH2 1 ATOM 4800 N N . LEU D 4 46 ? 20.931 48.737 -19.801 1.00 23.30 ? 45 LEU D N 1 ATOM 4801 C CA . LEU D 4 46 ? 21.521 48.662 -18.476 1.00 23.32 ? 45 LEU D CA 1 ATOM 4802 C C . LEU D 4 46 ? 22.611 49.714 -18.239 1.00 23.82 ? 45 LEU D C 1 ATOM 4803 O O . LEU D 4 46 ? 23.608 49.779 -18.970 1.00 24.28 ? 45 LEU D O 1 ATOM 4804 C CB . LEU D 4 46 ? 22.056 47.258 -18.225 1.00 22.22 ? 45 LEU D CB 1 ATOM 4805 C CG . LEU D 4 46 ? 22.457 46.932 -16.788 1.00 21.65 ? 45 LEU D CG 1 ATOM 4806 C CD1 . LEU D 4 46 ? 21.250 46.827 -15.864 1.00 21.08 ? 45 LEU D CD1 1 ATOM 4807 C CD2 . LEU D 4 46 ? 23.257 45.661 -16.804 1.00 20.65 ? 45 LEU D CD2 1 ATOM 4808 N N . ILE D 4 47 ? 22.405 50.532 -17.210 1.00 23.94 ? 46 ILE D N 1 ATOM 4809 C CA . ILE D 4 47 ? 23.361 51.558 -16.813 1.00 23.98 ? 46 ILE D CA 1 ATOM 4810 C C . ILE D 4 47 ? 24.340 50.986 -15.766 1.00 25.33 ? 46 ILE D C 1 ATOM 4811 O O . ILE D 4 47 ? 25.491 50.697 -16.077 1.00 26.64 ? 46 ILE D O 1 ATOM 4812 C CB . ILE D 4 47 ? 22.637 52.795 -16.249 1.00 23.63 ? 46 ILE D CB 1 ATOM 4813 C CG1 . ILE D 4 47 ? 21.723 53.422 -17.303 1.00 22.90 ? 46 ILE D CG1 1 ATOM 4814 C CG2 . ILE D 4 47 ? 23.647 53.822 -15.748 1.00 24.48 ? 46 ILE D CG2 1 ATOM 4815 C CD1 . ILE D 4 47 ? 20.642 54.336 -16.733 1.00 21.98 ? 46 ILE D CD1 1 ATOM 4816 N N . HIS D 4 48 ? 23.866 50.829 -14.530 1.00 26.06 ? 47 HIS D N 1 ATOM 4817 C CA . HIS D 4 48 ? 24.644 50.270 -13.425 1.00 25.00 ? 47 HIS D CA 1 ATOM 4818 C C . HIS D 4 48 ? 23.855 49.174 -12.780 1.00 23.96 ? 47 HIS D C 1 ATOM 4819 O O . HIS D 4 48 ? 22.635 49.060 -12.998 1.00 23.34 ? 47 HIS D O 1 ATOM 4820 C CB . HIS D 4 48 ? 24.988 51.359 -12.401 1.00 25.76 ? 47 HIS D CB 1 ATOM 4821 C CG . HIS D 4 48 ? 26.035 52.331 -12.886 1.00 27.13 ? 47 HIS D CG 1 ATOM 4822 N ND1 . HIS D 4 48 ? 27.339 52.011 -12.959 1.00 27.14 ? 47 HIS D ND1 1 ATOM 4823 C CD2 . HIS D 4 48 ? 25.923 53.642 -13.363 1.00 27.68 ? 47 HIS D CD2 1 ATOM 4824 C CE1 . HIS D 4 48 ? 28.032 53.061 -13.447 1.00 27.28 ? 47 HIS D CE1 1 ATOM 4825 N NE2 . HIS D 4 48 ? 27.164 54.057 -13.694 1.00 27.16 ? 47 HIS D NE2 1 ATOM 4826 N N . TYR D 4 49 ? 24.544 48.340 -12.004 1.00 23.05 ? 48 TYR D N 1 ATOM 4827 C CA . TYR D 4 49 ? 23.882 47.313 -11.197 1.00 23.31 ? 48 TYR D CA 1 ATOM 4828 C C . TYR D 4 49 ? 24.671 46.950 -9.936 1.00 24.23 ? 48 TYR D C 1 ATOM 4829 O O . TYR D 4 49 ? 25.825 47.377 -9.774 1.00 24.47 ? 48 TYR D O 1 ATOM 4830 C CB . TYR D 4 49 ? 23.540 46.067 -12.020 1.00 21.54 ? 48 TYR D CB 1 ATOM 4831 C CG . TYR D 4 49 ? 24.715 45.293 -12.566 1.00 20.80 ? 48 TYR D CG 1 ATOM 4832 C CD1 . TYR D 4 49 ? 25.148 44.104 -11.948 1.00 20.71 ? 48 TYR D CD1 1 ATOM 4833 C CD2 . TYR D 4 49 ? 25.381 45.720 -13.710 1.00 19.92 ? 48 TYR D CD2 1 ATOM 4834 C CE1 . TYR D 4 49 ? 26.217 43.384 -12.460 1.00 19.86 ? 48 TYR D CE1 1 ATOM 4835 C CE2 . TYR D 4 49 ? 26.445 45.013 -14.226 1.00 19.76 ? 48 TYR D CE2 1 ATOM 4836 C CZ . TYR D 4 49 ? 26.857 43.848 -13.606 1.00 20.13 ? 48 TYR D CZ 1 ATOM 4837 O OH . TYR D 4 49 ? 27.915 43.148 -14.143 1.00 20.71 ? 48 TYR D OH 1 ATOM 4838 N N . SER D 4 50 ? 24.046 46.173 -9.047 1.00 24.26 ? 49 SER D N 1 ATOM 4839 C CA . SER D 4 50 ? 24.648 45.896 -7.752 1.00 25.69 ? 49 SER D CA 1 ATOM 4840 C C . SER D 4 50 ? 24.284 44.524 -7.227 1.00 27.74 ? 49 SER D C 1 ATOM 4841 O O . SER D 4 50 ? 23.109 44.123 -7.251 1.00 28.02 ? 49 SER D O 1 ATOM 4842 C CB . SER D 4 50 ? 24.262 46.977 -6.736 1.00 25.63 ? 49 SER D CB 1 ATOM 4843 O OG . SER D 4 50 ? 24.642 46.625 -5.417 1.00 24.99 ? 49 SER D OG 1 ATOM 4844 N N . TYR D 4 51 ? 25.312 43.818 -6.748 1.00 29.83 ? 50 TYR D N 1 ATOM 4845 C CA . TYR D 4 51 ? 25.167 42.477 -6.185 1.00 31.46 ? 50 TYR D CA 1 ATOM 4846 C C . TYR D 4 51 ? 24.989 42.486 -4.650 1.00 33.85 ? 50 TYR D C 1 ATOM 4847 O O . TYR D 4 51 ? 24.666 41.462 -4.028 1.00 35.60 ? 50 TYR D O 1 ATOM 4848 C CB . TYR D 4 51 ? 26.356 41.610 -6.602 1.00 30.15 ? 50 TYR D CB 1 ATOM 4849 C CG . TYR D 4 51 ? 26.308 41.119 -8.039 1.00 28.56 ? 50 TYR D CG 1 ATOM 4850 C CD1 . TYR D 4 51 ? 25.186 40.446 -8.531 1.00 28.53 ? 50 TYR D CD1 1 ATOM 4851 C CD2 . TYR D 4 51 ? 27.389 41.305 -8.897 1.00 28.09 ? 50 TYR D CD2 1 ATOM 4852 C CE1 . TYR D 4 51 ? 25.129 39.979 -9.844 1.00 27.38 ? 50 TYR D CE1 1 ATOM 4853 C CE2 . TYR D 4 51 ? 27.349 40.837 -10.216 1.00 28.22 ? 50 TYR D CE2 1 ATOM 4854 C CZ . TYR D 4 51 ? 26.212 40.167 -10.679 1.00 27.69 ? 50 TYR D CZ 1 ATOM 4855 O OH . TYR D 4 51 ? 26.155 39.695 -11.973 1.00 26.31 ? 50 TYR D OH 1 ATOM 4856 N N . GLY D 4 52 ? 25.172 43.658 -4.052 1.00 34.14 ? 51 GLY D N 1 ATOM 4857 C CA . GLY D 4 52 ? 24.918 43.841 -2.634 1.00 34.47 ? 51 GLY D CA 1 ATOM 4858 C C . GLY D 4 52 ? 25.437 45.171 -2.127 1.00 35.63 ? 51 GLY D C 1 ATOM 4859 O O . GLY D 4 52 ? 26.164 45.896 -2.846 1.00 33.73 ? 51 GLY D O 1 ATOM 4860 N N . ALA D 4 53 ? 25.042 45.488 -0.889 1.00 35.37 ? 52 ALA D N 1 ATOM 4861 C CA . ALA D 4 53 ? 25.550 46.646 -0.147 1.00 34.69 ? 52 ALA D CA 1 ATOM 4862 C C . ALA D 4 53 ? 27.023 46.924 -0.442 1.00 34.55 ? 52 ALA D C 1 ATOM 4863 O O . ALA D 4 53 ? 27.846 46.010 -0.425 1.00 35.25 ? 52 ALA D O 1 ATOM 4864 C CB . ALA D 4 53 ? 25.341 46.429 1.341 1.00 34.99 ? 52 ALA D CB 1 ATOM 4865 N N . GLY D 4 54 ? 27.345 48.177 -0.754 1.00 35.37 ? 53 GLY D N 1 ATOM 4866 C CA . GLY D 4 54 ? 28.735 48.608 -0.954 1.00 34.21 ? 53 GLY D CA 1 ATOM 4867 C C . GLY D 4 54 ? 29.317 48.318 -2.323 1.00 36.49 ? 53 GLY D C 1 ATOM 4868 O O . GLY D 4 54 ? 30.394 48.827 -2.663 1.00 35.79 ? 53 GLY D O 1 ATOM 4869 N N . SER D 4 55 ? 28.614 47.493 -3.103 1.00 37.98 ? 54 SER D N 1 ATOM 4870 C CA . SER D 4 55 ? 29.051 47.114 -4.445 1.00 37.68 ? 54 SER D CA 1 ATOM 4871 C C . SER D 4 55 ? 28.164 47.740 -5.507 1.00 36.95 ? 54 SER D C 1 ATOM 4872 O O . SER D 4 55 ? 26.939 47.758 -5.390 1.00 37.69 ? 54 SER D O 1 ATOM 4873 C CB . SER D 4 55 ? 29.068 45.586 -4.615 1.00 40.89 ? 54 SER D CB 1 ATOM 4874 O OG . SER D 4 55 ? 28.712 45.192 -5.946 1.00 43.86 ? 54 SER D OG 1 ATOM 4875 N N . THR D 4 56 ? 28.808 48.251 -6.545 1.00 34.49 ? 55 THR D N 1 ATOM 4876 C CA . THR D 4 56 ? 28.129 48.760 -7.722 1.00 32.45 ? 55 THR D CA 1 ATOM 4877 C C . THR D 4 56 ? 28.958 48.295 -8.899 1.00 30.57 ? 55 THR D C 1 ATOM 4878 O O . THR D 4 56 ? 30.150 48.068 -8.749 1.00 28.57 ? 55 THR D O 1 ATOM 4879 C CB . THR D 4 56 ? 28.064 50.288 -7.721 1.00 32.72 ? 55 THR D CB 1 ATOM 4880 O OG1 . THR D 4 56 ? 29.365 50.808 -7.428 1.00 33.73 ? 55 THR D OG1 1 ATOM 4881 C CG2 . THR D 4 56 ? 27.081 50.786 -6.668 1.00 32.00 ? 55 THR D CG2 1 ATOM 4882 N N . GLU D 4 57 ? 28.314 48.116 -10.050 1.00 29.89 ? 56 GLU D N 1 ATOM 4883 C CA . GLU D 4 57 ? 28.960 47.589 -11.243 1.00 28.90 ? 56 GLU D CA 1 ATOM 4884 C C . GLU D 4 57 ? 28.501 48.333 -12.470 1.00 27.41 ? 56 GLU D C 1 ATOM 4885 O O . GLU D 4 57 ? 27.322 48.691 -12.584 1.00 27.03 ? 56 GLU D O 1 ATOM 4886 C CB . GLU D 4 57 ? 28.618 46.110 -11.429 1.00 30.52 ? 56 GLU D CB 1 ATOM 4887 C CG . GLU D 4 57 ? 29.160 45.193 -10.355 1.00 33.49 ? 56 GLU D CG 1 ATOM 4888 C CD . GLU D 4 57 ? 30.682 45.179 -10.284 1.00 35.35 ? 56 GLU D CD 1 ATOM 4889 O OE1 . GLU D 4 57 ? 31.341 45.525 -11.299 1.00 35.38 ? 56 GLU D OE1 1 ATOM 4890 O OE2 . GLU D 4 57 ? 31.210 44.810 -9.202 1.00 36.64 ? 56 GLU D OE2 1 ATOM 4891 N N . LYS D 4 58 ? 29.422 48.542 -13.403 1.00 25.95 ? 57 LYS D N 1 ATOM 4892 C CA . LYS D 4 58 ? 29.071 49.178 -14.659 1.00 26.34 ? 57 LYS D CA 1 ATOM 4893 C C . LYS D 4 58 ? 28.228 48.248 -15.527 1.00 26.06 ? 57 LYS D C 1 ATOM 4894 O O . LYS D 4 58 ? 28.437 47.048 -15.537 1.00 25.62 ? 57 LYS D O 1 ATOM 4895 C CB . LYS D 4 58 ? 30.320 49.608 -15.407 1.00 26.66 ? 57 LYS D CB 1 ATOM 4896 C CG . LYS D 4 58 ? 31.035 50.783 -14.792 1.00 27.98 ? 57 LYS D CG 1 ATOM 4897 C CD . LYS D 4 58 ? 32.279 51.088 -15.606 1.00 30.72 ? 57 LYS D CD 1 ATOM 4898 C CE . LYS D 4 58 ? 32.785 52.512 -15.399 1.00 31.47 ? 57 LYS D CE 1 ATOM 4899 N NZ . LYS D 4 58 ? 33.291 52.685 -14.004 1.00 32.77 ? 57 LYS D NZ 1 ATOM 4900 N N . GLY D 4 59 ? 27.256 48.818 -16.226 1.00 26.84 ? 58 GLY D N 1 ATOM 4901 C CA . GLY D 4 59 ? 26.440 48.090 -17.182 1.00 27.68 ? 58 GLY D CA 1 ATOM 4902 C C . GLY D 4 59 ? 26.886 48.424 -18.590 1.00 28.93 ? 58 GLY D C 1 ATOM 4903 O O . GLY D 4 59 ? 28.052 48.738 -18.813 1.00 28.67 ? 58 GLY D O 1 ATOM 4904 N N . ASP D 4 60 ? 25.962 48.359 -19.543 1.00 30.01 ? 59 ASP D N 1 ATOM 4905 C CA . ASP D 4 60 ? 26.300 48.597 -20.944 1.00 30.77 ? 59 ASP D CA 1 ATOM 4906 C C . ASP D 4 60 ? 26.492 50.075 -21.272 1.00 30.52 ? 59 ASP D C 1 ATOM 4907 O O . ASP D 4 60 ? 27.338 50.411 -22.100 1.00 31.51 ? 59 ASP D O 1 ATOM 4908 C CB . ASP D 4 60 ? 25.255 47.982 -21.873 1.00 32.81 ? 59 ASP D CB 1 ATOM 4909 C CG . ASP D 4 60 ? 25.123 46.475 -21.697 1.00 36.06 ? 59 ASP D CG 1 ATOM 4910 O OD1 . ASP D 4 60 ? 26.142 45.788 -21.436 1.00 38.97 ? 59 ASP D OD1 1 ATOM 4911 O OD2 . ASP D 4 60 ? 23.989 45.967 -21.832 1.00 37.24 ? 59 ASP D OD2 1 ATOM 4912 N N . ILE D 4 61 ? 25.713 50.956 -20.635 1.00 28.81 ? 60 ILE D N 1 ATOM 4913 C CA . ILE D 4 61 ? 25.831 52.402 -20.884 1.00 26.13 ? 60 ILE D CA 1 ATOM 4914 C C . ILE D 4 61 ? 26.089 53.235 -19.627 1.00 25.81 ? 60 ILE D C 1 ATOM 4915 O O . ILE D 4 61 ? 25.291 54.102 -19.270 1.00 25.32 ? 60 ILE D O 1 ATOM 4916 C CB . ILE D 4 61 ? 24.638 52.966 -21.683 1.00 25.00 ? 60 ILE D CB 1 ATOM 4917 C CG1 . ILE D 4 61 ? 23.302 52.639 -21.009 1.00 24.45 ? 60 ILE D CG1 1 ATOM 4918 C CG2 . ILE D 4 61 ? 24.681 52.459 -23.108 1.00 25.10 ? 60 ILE D CG2 1 ATOM 4919 C CD1 . ILE D 4 61 ? 22.167 53.548 -21.433 1.00 22.94 ? 60 ILE D CD1 1 ATOM 4920 N N . PRO D 4 62 ? 27.237 53.000 -18.970 1.00 26.05 ? 61 PRO D N 1 ATOM 4921 C CA . PRO D 4 62 ? 27.471 53.607 -17.656 1.00 25.56 ? 61 PRO D CA 1 ATOM 4922 C C . PRO D 4 62 ? 27.880 55.077 -17.660 1.00 25.72 ? 61 PRO D C 1 ATOM 4923 O O . PRO D 4 62 ? 27.628 55.748 -16.673 1.00 25.96 ? 61 PRO D O 1 ATOM 4924 C CB . PRO D 4 62 ? 28.593 52.745 -17.074 1.00 24.82 ? 61 PRO D CB 1 ATOM 4925 C CG . PRO D 4 62 ? 29.342 52.261 -18.236 1.00 24.24 ? 61 PRO D CG 1 ATOM 4926 C CD . PRO D 4 62 ? 28.393 52.202 -19.418 1.00 25.06 ? 61 PRO D CD 1 ATOM 4927 N N . ASP D 4 63 ? 28.484 55.570 -18.747 1.00 26.89 ? 62 ASP D N 1 ATOM 4928 C CA . ASP D 4 63 ? 28.981 56.958 -18.836 1.00 28.76 ? 62 ASP D CA 1 ATOM 4929 C C . ASP D 4 63 ? 27.990 58.071 -18.462 1.00 27.77 ? 62 ASP D C 1 ATOM 4930 O O . ASP D 4 63 ? 26.904 58.179 -19.025 1.00 28.21 ? 62 ASP D O 1 ATOM 4931 C CB . ASP D 4 63 ? 29.514 57.249 -20.244 1.00 32.65 ? 62 ASP D CB 1 ATOM 4932 C CG . ASP D 4 63 ? 30.750 56.433 -20.590 1.00 37.43 ? 62 ASP D CG 1 ATOM 4933 O OD1 . ASP D 4 63 ? 31.135 56.424 -21.785 1.00 37.33 ? 62 ASP D OD1 1 ATOM 4934 O OD2 . ASP D 4 63 ? 31.336 55.801 -19.673 1.00 40.27 ? 62 ASP D OD2 1 ATOM 4935 N N . GLY D 4 64 ? 28.391 58.919 -17.528 1.00 26.34 ? 63 GLY D N 1 ATOM 4936 C CA . GLY D 4 64 ? 27.591 60.066 -17.152 1.00 24.87 ? 63 GLY D CA 1 ATOM 4937 C C . GLY D 4 64 ? 26.860 59.788 -15.869 1.00 25.71 ? 63 GLY D C 1 ATOM 4938 O O . GLY D 4 64 ? 26.362 60.703 -15.219 1.00 26.49 ? 63 GLY D O 1 ATOM 4939 N N . TYR D 4 65 ? 26.779 58.508 -15.509 1.00 26.18 ? 64 TYR D N 1 ATOM 4940 C CA . TYR D 4 65 ? 26.072 58.085 -14.304 1.00 25.51 ? 64 TYR D CA 1 ATOM 4941 C C . TYR D 4 65 ? 27.035 57.467 -13.321 1.00 26.71 ? 64 TYR D C 1 ATOM 4942 O O . TYR D 4 65 ? 28.014 56.844 -13.705 1.00 25.88 ? 64 TYR D O 1 ATOM 4943 C CB . TYR D 4 65 ? 25.001 57.052 -14.627 1.00 23.84 ? 64 TYR D CB 1 ATOM 4944 C CG . TYR D 4 65 ? 23.992 57.483 -15.653 1.00 22.52 ? 64 TYR D CG 1 ATOM 4945 C CD1 . TYR D 4 65 ? 22.863 58.196 -15.282 1.00 22.22 ? 64 TYR D CD1 1 ATOM 4946 C CD2 . TYR D 4 65 ? 24.157 57.158 -16.995 1.00 21.61 ? 64 TYR D CD2 1 ATOM 4947 C CE1 . TYR D 4 65 ? 21.935 58.596 -16.225 1.00 21.67 ? 64 TYR D CE1 1 ATOM 4948 C CE2 . TYR D 4 65 ? 23.233 57.539 -17.935 1.00 21.14 ? 64 TYR D CE2 1 ATOM 4949 C CZ . TYR D 4 65 ? 22.128 58.261 -17.546 1.00 21.27 ? 64 TYR D CZ 1 ATOM 4950 O OH . TYR D 4 65 ? 21.202 58.639 -18.479 1.00 21.58 ? 64 TYR D OH 1 ATOM 4951 N N . LYS D 4 66 ? 26.727 57.640 -12.047 1.00 28.92 ? 65 LYS D N 1 ATOM 4952 C CA . LYS D 4 66 ? 27.468 57.034 -10.971 1.00 30.82 ? 65 LYS D CA 1 ATOM 4953 C C . LYS D 4 66 ? 26.411 56.325 -10.118 1.00 30.62 ? 65 LYS D C 1 ATOM 4954 O O . LYS D 4 66 ? 25.299 56.831 -9.975 1.00 30.98 ? 65 LYS D O 1 ATOM 4955 C CB . LYS D 4 66 ? 28.196 58.133 -10.195 1.00 33.34 ? 65 LYS D CB 1 ATOM 4956 C CG . LYS D 4 66 ? 29.101 57.661 -9.066 1.00 37.43 ? 65 LYS D CG 1 ATOM 4957 C CD . LYS D 4 66 ? 29.790 58.845 -8.375 1.00 40.73 ? 65 LYS D CD 1 ATOM 4958 C CE . LYS D 4 66 ? 30.937 58.375 -7.484 1.00 43.69 ? 65 LYS D CE 1 ATOM 4959 N NZ . LYS D 4 66 ? 31.539 59.520 -6.740 1.00 46.92 ? 65 LYS D NZ 1 ATOM 4960 N N . ALA D 4 67 ? 26.736 55.152 -9.586 1.00 29.12 ? 66 ALA D N 1 ATOM 4961 C CA . ALA D 4 67 ? 25.777 54.392 -8.802 1.00 28.98 ? 66 ALA D CA 1 ATOM 4962 C C . ALA D 4 67 ? 26.208 54.363 -7.358 1.00 29.62 ? 66 ALA D C 1 ATOM 4963 O O . ALA D 4 67 ? 27.375 54.556 -7.073 1.00 32.14 ? 66 ALA D O 1 ATOM 4964 C CB . ALA D 4 67 ? 25.643 52.991 -9.337 1.00 29.85 ? 66 ALA D CB 1 ATOM 4965 N N . SER D 4 68 ? 25.263 54.133 -6.451 1.00 29.37 ? 67 SER D N 1 ATOM 4966 C CA . SER D 4 68 ? 25.541 54.064 -5.024 1.00 29.50 ? 67 SER D CA 1 ATOM 4967 C C . SER D 4 68 ? 24.606 53.058 -4.350 1.00 30.76 ? 67 SER D C 1 ATOM 4968 O O . SER D 4 68 ? 23.375 53.150 -4.443 1.00 30.34 ? 67 SER D O 1 ATOM 4969 C CB . SER D 4 68 ? 25.417 55.455 -4.378 1.00 29.86 ? 67 SER D CB 1 ATOM 4970 O OG . SER D 4 68 ? 25.332 55.403 -2.954 1.00 28.86 ? 67 SER D OG 1 ATOM 4971 N N . ARG D 4 69 ? 25.200 52.091 -3.668 1.00 31.27 ? 68 ARG D N 1 ATOM 4972 C CA . ARG D 4 69 ? 24.413 51.111 -2.950 1.00 33.76 ? 68 ARG D CA 1 ATOM 4973 C C . ARG D 4 69 ? 24.824 51.152 -1.475 1.00 36.65 ? 68 ARG D C 1 ATOM 4974 O O . ARG D 4 69 ? 25.671 50.368 -1.035 1.00 37.88 ? 68 ARG D O 1 ATOM 4975 C CB . ARG D 4 69 ? 24.593 49.713 -3.575 1.00 31.44 ? 68 ARG D CB 1 ATOM 4976 C CG . ARG D 4 69 ? 23.695 48.640 -2.999 1.00 28.89 ? 68 ARG D CG 1 ATOM 4977 C CD . ARG D 4 69 ? 22.359 48.564 -3.717 1.00 27.88 ? 68 ARG D CD 1 ATOM 4978 N NE . ARG D 4 69 ? 21.462 47.607 -3.079 1.00 26.16 ? 68 ARG D NE 1 ATOM 4979 C CZ . ARG D 4 69 ? 21.467 46.304 -3.314 1.00 24.87 ? 68 ARG D CZ 1 ATOM 4980 N NH1 . ARG D 4 69 ? 22.317 45.800 -4.191 1.00 24.41 ? 68 ARG D NH1 1 ATOM 4981 N NH2 . ARG D 4 69 ? 20.620 45.509 -2.676 1.00 24.65 ? 68 ARG D NH2 1 ATOM 4982 N N . PRO D 4 70 ? 24.247 52.097 -0.710 1.00 38.67 ? 69 PRO D N 1 ATOM 4983 C CA . PRO D 4 70 ? 24.513 52.190 0.728 1.00 39.29 ? 69 PRO D CA 1 ATOM 4984 C C . PRO D 4 70 ? 23.988 51.007 1.548 1.00 39.36 ? 69 PRO D C 1 ATOM 4985 O O . PRO D 4 70 ? 24.561 50.681 2.585 1.00 40.41 ? 69 PRO D O 1 ATOM 4986 C CB . PRO D 4 70 ? 23.767 53.467 1.134 1.00 39.63 ? 69 PRO D CB 1 ATOM 4987 C CG . PRO D 4 70 ? 22.727 53.655 0.084 1.00 39.16 ? 69 PRO D CG 1 ATOM 4988 C CD . PRO D 4 70 ? 23.412 53.219 -1.171 1.00 38.81 ? 69 PRO D CD 1 ATOM 4989 N N . SER D 4 71 ? 22.912 50.375 1.091 1.00 38.64 ? 70 SER D N 1 ATOM 4990 C CA . SER D 4 71 ? 22.277 49.313 1.866 1.00 39.16 ? 70 SER D CA 1 ATOM 4991 C C . SER D 4 71 ? 21.575 48.277 0.990 1.00 38.72 ? 70 SER D C 1 ATOM 4992 O O . SER D 4 71 ? 21.452 48.464 -0.217 1.00 41.30 ? 70 SER D O 1 ATOM 4993 C CB . SER D 4 71 ? 21.288 49.925 2.869 1.00 39.06 ? 70 SER D CB 1 ATOM 4994 O OG . SER D 4 71 ? 20.293 50.692 2.219 1.00 37.87 ? 70 SER D OG 1 ATOM 4995 N N . GLN D 4 72 ? 21.109 47.196 1.607 1.00 37.48 ? 71 GLN D N 1 ATOM 4996 C CA . GLN D 4 72 ? 20.416 46.135 0.901 1.00 38.60 ? 71 GLN D CA 1 ATOM 4997 C C . GLN D 4 72 ? 19.158 46.653 0.210 1.00 40.29 ? 71 GLN D C 1 ATOM 4998 O O . GLN D 4 72 ? 18.807 46.182 -0.872 1.00 40.66 ? 71 GLN D O 1 ATOM 4999 C CB . GLN D 4 72 ? 20.089 44.984 1.867 1.00 39.59 ? 71 GLN D CB 1 ATOM 5000 C CG . GLN D 4 72 ? 19.420 43.719 1.252 1.00 39.17 ? 71 GLN D CG 1 ATOM 5001 C CD . GLN D 4 72 ? 20.379 42.795 0.481 1.00 38.37 ? 71 GLN D CD 1 ATOM 5002 O OE1 . GLN D 4 72 ? 21.518 43.154 0.154 1.00 35.64 ? 71 GLN D OE1 1 ATOM 5003 N NE2 . GLN D 4 72 ? 19.897 41.594 0.180 1.00 38.18 ? 71 GLN D NE2 1 ATOM 5004 N N . GLU D 4 73 ? 18.503 47.640 0.821 1.00 43.08 ? 72 GLU D N 1 ATOM 5005 C CA . GLU D 4 73 ? 17.221 48.184 0.304 1.00 43.57 ? 72 GLU D CA 1 ATOM 5006 C C . GLU D 4 73 ? 17.312 49.392 -0.654 1.00 40.33 ? 72 GLU D C 1 ATOM 5007 O O . GLU D 4 73 ? 16.378 49.621 -1.418 1.00 37.19 ? 72 GLU D O 1 ATOM 5008 C CB . GLU D 4 73 ? 16.209 48.454 1.438 1.00 47.91 ? 72 GLU D CB 1 ATOM 5009 C CG . GLU D 4 73 ? 16.807 48.899 2.774 1.00 56.14 ? 72 GLU D CG 1 ATOM 5010 C CD . GLU D 4 73 ? 17.727 47.846 3.400 1.00 62.97 ? 72 GLU D CD 1 ATOM 5011 O OE1 . GLU D 4 73 ? 18.839 48.215 3.837 1.00 67.79 ? 72 GLU D OE1 1 ATOM 5012 O OE2 . GLU D 4 73 ? 17.354 46.649 3.438 1.00 65.81 ? 72 GLU D OE2 1 ATOM 5013 N N . ASN D 4 74 ? 18.424 50.139 -0.629 1.00 37.39 ? 73 ASN D N 1 ATOM 5014 C CA . ASN D 4 74 ? 18.587 51.314 -1.492 1.00 35.27 ? 73 ASN D CA 1 ATOM 5015 C C . ASN D 4 74 ? 19.648 51.194 -2.573 1.00 35.73 ? 73 ASN D C 1 ATOM 5016 O O . ASN D 4 74 ? 20.834 50.972 -2.291 1.00 36.51 ? 73 ASN D O 1 ATOM 5017 C CB . ASN D 4 74 ? 18.852 52.580 -0.680 1.00 35.51 ? 73 ASN D CB 1 ATOM 5018 C CG . ASN D 4 74 ? 17.695 52.949 0.223 1.00 37.41 ? 73 ASN D CG 1 ATOM 5019 O OD1 . ASN D 4 74 ? 16.530 52.942 -0.190 1.00 37.84 ? 73 ASN D OD1 1 ATOM 5020 N ND2 . ASN D 4 74 ? 18.010 53.280 1.474 1.00 38.06 ? 73 ASN D ND2 1 ATOM 5021 N N . PHE D 4 75 ? 19.197 51.352 -3.816 1.00 33.92 ? 74 PHE D N 1 ATOM 5022 C CA . PHE D 4 75 ? 20.077 51.541 -4.967 1.00 31.29 ? 74 PHE D CA 1 ATOM 5023 C C . PHE D 4 75 ? 19.697 52.884 -5.540 1.00 29.98 ? 74 PHE D C 1 ATOM 5024 O O . PHE D 4 75 ? 18.510 53.178 -5.724 1.00 29.92 ? 74 PHE D O 1 ATOM 5025 C CB . PHE D 4 75 ? 19.880 50.437 -6.018 1.00 29.89 ? 74 PHE D CB 1 ATOM 5026 C CG . PHE D 4 75 ? 20.999 50.329 -7.034 1.00 28.40 ? 74 PHE D CG 1 ATOM 5027 C CD1 . PHE D 4 75 ? 22.298 50.739 -6.730 1.00 28.14 ? 74 PHE D CD1 1 ATOM 5028 C CD2 . PHE D 4 75 ? 20.757 49.761 -8.282 1.00 28.11 ? 74 PHE D CD2 1 ATOM 5029 C CE1 . PHE D 4 75 ? 23.322 50.622 -7.666 1.00 27.66 ? 74 PHE D CE1 1 ATOM 5030 C CE2 . PHE D 4 75 ? 21.774 49.626 -9.224 1.00 27.14 ? 74 PHE D CE2 1 ATOM 5031 C CZ . PHE D 4 75 ? 23.057 50.057 -8.918 1.00 27.75 ? 74 PHE D CZ 1 ATOM 5032 N N . SER D 4 76 ? 20.713 53.693 -5.811 1.00 28.48 ? 75 SER D N 1 ATOM 5033 C CA . SER D 4 76 ? 20.525 55.080 -6.178 1.00 27.44 ? 75 SER D CA 1 ATOM 5034 C C . SER D 4 76 ? 21.375 55.480 -7.399 1.00 27.06 ? 75 SER D C 1 ATOM 5035 O O . SER D 4 76 ? 22.581 55.214 -7.463 1.00 26.51 ? 75 SER D O 1 ATOM 5036 C CB . SER D 4 76 ? 20.779 55.958 -4.941 1.00 28.61 ? 75 SER D CB 1 ATOM 5037 O OG . SER D 4 76 ? 21.489 57.152 -5.231 1.00 31.16 ? 75 SER D OG 1 ATOM 5038 N N . LEU D 4 77 ? 20.726 56.094 -8.381 1.00 26.22 ? 76 LEU D N 1 ATOM 5039 C CA . LEU D 4 77 ? 21.410 56.538 -9.584 1.00 26.66 ? 76 LEU D CA 1 ATOM 5040 C C . LEU D 4 77 ? 21.698 58.026 -9.497 1.00 28.08 ? 76 LEU D C 1 ATOM 5041 O O . LEU D 4 77 ? 20.774 58.856 -9.483 1.00 29.38 ? 76 LEU D O 1 ATOM 5042 C CB . LEU D 4 77 ? 20.584 56.225 -10.834 1.00 25.24 ? 76 LEU D CB 1 ATOM 5043 C CG . LEU D 4 77 ? 21.325 56.367 -12.159 1.00 24.05 ? 76 LEU D CG 1 ATOM 5044 C CD1 . LEU D 4 77 ? 22.274 55.225 -12.315 1.00 23.35 ? 76 LEU D CD1 1 ATOM 5045 C CD2 . LEU D 4 77 ? 20.331 56.374 -13.299 1.00 24.55 ? 76 LEU D CD2 1 ATOM 5046 N N . ILE D 4 78 ? 22.986 58.347 -9.446 1.00 28.65 ? 77 ILE D N 1 ATOM 5047 C CA . ILE D 4 78 ? 23.457 59.716 -9.284 1.00 29.38 ? 77 ILE D CA 1 ATOM 5048 C C . ILE D 4 78 ? 23.950 60.268 -10.616 1.00 29.69 ? 77 ILE D C 1 ATOM 5049 O O . ILE D 4 78 ? 24.818 59.684 -11.269 1.00 29.78 ? 77 ILE D O 1 ATOM 5050 C CB . ILE D 4 78 ? 24.587 59.787 -8.224 1.00 29.61 ? 77 ILE D CB 1 ATOM 5051 C CG1 . ILE D 4 78 ? 24.078 59.305 -6.862 1.00 29.86 ? 77 ILE D CG1 1 ATOM 5052 C CG2 . ILE D 4 78 ? 25.130 61.191 -8.112 1.00 30.11 ? 77 ILE D CG2 1 ATOM 5053 C CD1 . ILE D 4 78 ? 25.175 58.855 -5.891 1.00 29.45 ? 77 ILE D CD1 1 ATOM 5054 N N . LEU D 4 79 ? 23.367 61.389 -11.021 1.00 31.50 ? 78 LEU D N 1 ATOM 5055 C CA . LEU D 4 79 ? 23.820 62.135 -12.189 1.00 33.57 ? 78 LEU D CA 1 ATOM 5056 C C . LEU D 4 79 ? 24.535 63.396 -11.672 1.00 37.24 ? 78 LEU D C 1 ATOM 5057 O O . LEU D 4 79 ? 23.895 64.334 -11.180 1.00 37.49 ? 78 LEU D O 1 ATOM 5058 C CB . LEU D 4 79 ? 22.640 62.493 -13.103 1.00 31.39 ? 78 LEU D CB 1 ATOM 5059 C CG . LEU D 4 79 ? 21.925 61.425 -13.949 1.00 30.00 ? 78 LEU D CG 1 ATOM 5060 C CD1 . LEU D 4 79 ? 21.201 60.388 -13.111 1.00 29.97 ? 78 LEU D CD1 1 ATOM 5061 C CD2 . LEU D 4 79 ? 20.934 62.054 -14.916 1.00 29.21 ? 78 LEU D CD2 1 ATOM 5062 N N . GLU D 4 80 ? 25.866 63.388 -11.760 1.00 40.90 ? 79 GLU D N 1 ATOM 5063 C CA . GLU D 4 80 ? 26.705 64.439 -11.187 1.00 42.32 ? 79 GLU D CA 1 ATOM 5064 C C . GLU D 4 80 ? 26.564 65.759 -11.962 1.00 42.64 ? 79 GLU D C 1 ATOM 5065 O O . GLU D 4 80 ? 26.175 66.766 -11.395 1.00 46.49 ? 79 GLU D O 1 ATOM 5066 C CB . GLU D 4 80 ? 28.160 63.971 -11.115 1.00 42.75 ? 79 GLU D CB 1 ATOM 5067 C CG . GLU D 4 80 ? 28.860 64.370 -9.842 1.00 45.80 ? 79 GLU D CG 1 ATOM 5068 C CD . GLU D 4 80 ? 28.484 63.485 -8.671 1.00 50.86 ? 79 GLU D CD 1 ATOM 5069 O OE1 . GLU D 4 80 ? 28.889 62.305 -8.677 1.00 56.60 ? 79 GLU D OE1 1 ATOM 5070 O OE2 . GLU D 4 80 ? 27.795 63.959 -7.736 1.00 52.01 ? 79 GLU D OE2 1 ATOM 5071 N N . LEU D 4 81 ? 26.850 65.743 -13.259 1.00 42.61 ? 80 LEU D N 1 ATOM 5072 C CA . LEU D 4 81 ? 26.597 66.896 -14.122 1.00 41.01 ? 80 LEU D CA 1 ATOM 5073 C C . LEU D 4 81 ? 25.595 66.523 -15.214 1.00 40.05 ? 80 LEU D C 1 ATOM 5074 O O . LEU D 4 81 ? 25.963 65.955 -16.240 1.00 41.96 ? 80 LEU D O 1 ATOM 5075 C CB . LEU D 4 81 ? 27.902 67.400 -14.756 1.00 43.11 ? 80 LEU D CB 1 ATOM 5076 C CG . LEU D 4 81 ? 29.085 67.726 -13.836 1.00 44.06 ? 80 LEU D CG 1 ATOM 5077 C CD1 . LEU D 4 81 ? 30.411 67.604 -14.600 1.00 43.42 ? 80 LEU D CD1 1 ATOM 5078 C CD2 . LEU D 4 81 ? 28.925 69.094 -13.169 1.00 42.04 ? 80 LEU D CD2 1 ATOM 5079 N N . ALA D 4 82 ? 24.327 66.848 -14.986 1.00 38.47 ? 81 ALA D N 1 ATOM 5080 C CA . ALA D 4 82 ? 23.242 66.442 -15.877 1.00 36.78 ? 81 ALA D CA 1 ATOM 5081 C C . ALA D 4 82 ? 23.330 67.099 -17.255 1.00 36.85 ? 81 ALA D C 1 ATOM 5082 O O . ALA D 4 82 ? 23.794 68.241 -17.382 1.00 38.12 ? 81 ALA D O 1 ATOM 5083 C CB . ALA D 4 82 ? 21.888 66.727 -15.228 1.00 34.41 ? 81 ALA D CB 1 ATOM 5084 N N . THR D 4 83 ? 22.885 66.374 -18.281 1.00 34.42 ? 82 THR D N 1 ATOM 5085 C CA . THR D 4 83 ? 22.849 66.909 -19.645 1.00 33.86 ? 82 THR D CA 1 ATOM 5086 C C . THR D 4 83 ? 21.543 66.516 -20.343 1.00 31.35 ? 82 THR D C 1 ATOM 5087 O O . THR D 4 83 ? 20.951 65.507 -19.990 1.00 31.56 ? 82 THR D O 1 ATOM 5088 C CB . THR D 4 83 ? 24.048 66.402 -20.501 1.00 35.09 ? 82 THR D CB 1 ATOM 5089 O OG1 . THR D 4 83 ? 23.690 65.174 -21.160 1.00 36.96 ? 82 THR D OG1 1 ATOM 5090 C CG2 . THR D 4 83 ? 25.329 66.214 -19.649 1.00 33.22 ? 82 THR D CG2 1 ATOM 5091 N N . PRO D 4 84 ? 21.109 67.291 -21.359 1.00 29.87 ? 83 PRO D N 1 ATOM 5092 C CA . PRO D 4 84 ? 19.872 67.002 -22.084 1.00 28.71 ? 83 PRO D CA 1 ATOM 5093 C C . PRO D 4 84 ? 19.773 65.559 -22.590 1.00 29.18 ? 83 PRO D C 1 ATOM 5094 O O . PRO D 4 84 ? 18.678 64.985 -22.615 1.00 28.14 ? 83 PRO D O 1 ATOM 5095 C CB . PRO D 4 84 ? 19.945 67.956 -23.272 1.00 28.28 ? 83 PRO D CB 1 ATOM 5096 C CG . PRO D 4 84 ? 20.773 69.075 -22.804 1.00 27.91 ? 83 PRO D CG 1 ATOM 5097 C CD . PRO D 4 84 ? 21.810 68.453 -21.941 1.00 29.41 ? 83 PRO D CD 1 ATOM 5098 N N . SER D 4 85 ? 20.912 64.982 -22.977 1.00 30.00 ? 84 SER D N 1 ATOM 5099 C CA . SER D 4 85 ? 20.971 63.609 -23.476 1.00 29.64 ? 84 SER D CA 1 ATOM 5100 C C . SER D 4 85 ? 20.508 62.590 -22.426 1.00 30.37 ? 84 SER D C 1 ATOM 5101 O O . SER D 4 85 ? 20.198 61.447 -22.769 1.00 31.68 ? 84 SER D O 1 ATOM 5102 C CB . SER D 4 85 ? 22.389 63.277 -23.945 1.00 29.49 ? 84 SER D CB 1 ATOM 5103 O OG . SER D 4 85 ? 23.185 62.789 -22.875 1.00 29.87 ? 84 SER D OG 1 ATOM 5104 N N . GLN D 4 86 ? 20.469 63.005 -21.156 1.00 29.83 ? 85 GLN D N 1 ATOM 5105 C CA . GLN D 4 86 ? 20.002 62.142 -20.059 1.00 29.11 ? 85 GLN D CA 1 ATOM 5106 C C . GLN D 4 86 ? 18.501 62.258 -19.769 1.00 28.28 ? 85 GLN D C 1 ATOM 5107 O O . GLN D 4 86 ? 18.009 61.679 -18.805 1.00 28.62 ? 85 GLN D O 1 ATOM 5108 C CB . GLN D 4 86 ? 20.803 62.405 -18.793 1.00 29.21 ? 85 GLN D CB 1 ATOM 5109 C CG . GLN D 4 86 ? 22.248 61.993 -18.912 1.00 31.71 ? 85 GLN D CG 1 ATOM 5110 C CD . GLN D 4 86 ? 23.047 62.361 -17.691 1.00 33.89 ? 85 GLN D CD 1 ATOM 5111 O OE1 . GLN D 4 86 ? 22.988 63.501 -17.220 1.00 35.13 ? 85 GLN D OE1 1 ATOM 5112 N NE2 . GLN D 4 86 ? 23.806 61.400 -17.162 1.00 33.96 ? 85 GLN D NE2 1 ATOM 5113 N N . THR D 4 87 ? 17.795 63.026 -20.593 1.00 26.64 ? 86 THR D N 1 ATOM 5114 C CA . THR D 4 87 ? 16.346 63.061 -20.597 1.00 26.25 ? 86 THR D CA 1 ATOM 5115 C C . THR D 4 87 ? 15.861 61.697 -21.061 1.00 26.34 ? 86 THR D C 1 ATOM 5116 O O . THR D 4 87 ? 16.246 61.227 -22.131 1.00 26.38 ? 86 THR D O 1 ATOM 5117 C CB . THR D 4 87 ? 15.835 64.166 -21.571 1.00 26.93 ? 86 THR D CB 1 ATOM 5118 O OG1 . THR D 4 87 ? 16.057 65.458 -20.987 1.00 28.51 ? 86 THR D OG1 1 ATOM 5119 C CG2 . THR D 4 87 ? 14.355 63.996 -21.932 1.00 24.46 ? 86 THR D CG2 1 ATOM 5120 N N . SER D 4 88 ? 15.003 61.076 -20.257 1.00 26.43 ? 87 SER D N 1 ATOM 5121 C CA . SER D 4 88 ? 14.610 59.693 -20.454 1.00 25.40 ? 87 SER D CA 1 ATOM 5122 C C . SER D 4 88 ? 13.659 59.250 -19.354 1.00 24.94 ? 87 SER D C 1 ATOM 5123 O O . SER D 4 88 ? 13.259 60.041 -18.491 1.00 24.69 ? 87 SER D O 1 ATOM 5124 C CB . SER D 4 88 ? 15.855 58.788 -20.418 1.00 26.25 ? 87 SER D CB 1 ATOM 5125 O OG . SER D 4 88 ? 15.524 57.454 -20.783 1.00 27.39 ? 87 SER D OG 1 ATOM 5126 N N . VAL D 4 89 ? 13.308 57.967 -19.392 1.00 23.52 ? 88 VAL D N 1 ATOM 5127 C CA . VAL D 4 89 ? 12.520 57.336 -18.348 1.00 22.36 ? 88 VAL D CA 1 ATOM 5128 C C . VAL D 4 89 ? 13.382 56.217 -17.742 1.00 22.24 ? 88 VAL D C 1 ATOM 5129 O O . VAL D 4 89 ? 13.868 55.336 -18.456 1.00 21.28 ? 88 VAL D O 1 ATOM 5130 C CB . VAL D 4 89 ? 11.187 56.812 -18.918 1.00 21.33 ? 88 VAL D CB 1 ATOM 5131 C CG1 . VAL D 4 89 ? 10.406 55.998 -17.891 1.00 20.56 ? 88 VAL D CG1 1 ATOM 5132 C CG2 . VAL D 4 89 ? 10.366 57.976 -19.433 1.00 21.08 ? 88 VAL D CG2 1 ATOM 5133 N N . TYR D 4 90 ? 13.590 56.282 -16.430 1.00 22.32 ? 89 TYR D N 1 ATOM 5134 C CA . TYR D 4 90 ? 14.515 55.374 -15.759 1.00 23.14 ? 89 TYR D CA 1 ATOM 5135 C C . TYR D 4 90 ? 13.777 54.304 -14.966 1.00 24.43 ? 89 TYR D C 1 ATOM 5136 O O . TYR D 4 90 ? 12.841 54.608 -14.219 1.00 26.45 ? 89 TYR D O 1 ATOM 5137 C CB . TYR D 4 90 ? 15.495 56.149 -14.872 1.00 22.03 ? 89 TYR D CB 1 ATOM 5138 C CG . TYR D 4 90 ? 16.414 57.065 -15.663 1.00 21.75 ? 89 TYR D CG 1 ATOM 5139 C CD1 . TYR D 4 90 ? 15.959 58.302 -16.153 1.00 21.24 ? 89 TYR D CD1 1 ATOM 5140 C CD2 . TYR D 4 90 ? 17.739 56.693 -15.935 1.00 21.76 ? 89 TYR D CD2 1 ATOM 5141 C CE1 . TYR D 4 90 ? 16.794 59.141 -16.894 1.00 20.72 ? 89 TYR D CE1 1 ATOM 5142 C CE2 . TYR D 4 90 ? 18.587 57.527 -16.676 1.00 21.02 ? 89 TYR D CE2 1 ATOM 5143 C CZ . TYR D 4 90 ? 18.106 58.749 -17.145 1.00 20.68 ? 89 TYR D CZ 1 ATOM 5144 O OH . TYR D 4 90 ? 18.937 59.574 -17.854 1.00 20.37 ? 89 TYR D OH 1 ATOM 5145 N N . PHE D 4 91 ? 14.186 53.052 -15.154 1.00 23.81 ? 90 PHE D N 1 ATOM 5146 C CA . PHE D 4 91 ? 13.597 51.949 -14.426 1.00 23.82 ? 90 PHE D CA 1 ATOM 5147 C C . PHE D 4 91 ? 14.607 51.290 -13.511 1.00 25.14 ? 90 PHE D C 1 ATOM 5148 O O . PHE D 4 91 ? 15.741 51.019 -13.892 1.00 25.16 ? 90 PHE D O 1 ATOM 5149 C CB . PHE D 4 91 ? 12.989 50.922 -15.375 1.00 22.89 ? 90 PHE D CB 1 ATOM 5150 C CG . PHE D 4 91 ? 11.719 51.375 -16.007 1.00 22.15 ? 90 PHE D CG 1 ATOM 5151 C CD1 . PHE D 4 91 ? 10.509 51.228 -15.336 1.00 21.97 ? 90 PHE D CD1 1 ATOM 5152 C CD2 . PHE D 4 91 ? 11.727 51.957 -17.271 1.00 21.56 ? 90 PHE D CD2 1 ATOM 5153 C CE1 . PHE D 4 91 ? 9.316 51.670 -15.911 1.00 21.90 ? 90 PHE D CE1 1 ATOM 5154 C CE2 . PHE D 4 91 ? 10.541 52.404 -17.858 1.00 21.44 ? 90 PHE D CE2 1 ATOM 5155 C CZ . PHE D 4 91 ? 9.336 52.272 -17.177 1.00 21.36 ? 90 PHE D CZ 1 ATOM 5156 N N . CYS D 4 92 ? 14.169 51.046 -12.287 1.00 28.28 ? 91 CYS D N 1 ATOM 5157 C CA . CYS D 4 92 ? 14.945 50.341 -11.304 1.00 29.39 ? 91 CYS D CA 1 ATOM 5158 C C . CYS D 4 92 ? 14.391 48.947 -11.206 1.00 28.55 ? 91 CYS D C 1 ATOM 5159 O O . CYS D 4 92 ? 13.185 48.760 -11.337 1.00 27.78 ? 91 CYS D O 1 ATOM 5160 C CB . CYS D 4 92 ? 14.774 51.011 -9.955 1.00 33.80 ? 91 CYS D CB 1 ATOM 5161 S SG . CYS D 4 92 ? 15.586 50.045 -8.729 1.00 45.45 ? 91 CYS D SG 1 ATOM 5162 N N . ALA D 4 93 ? 15.250 47.961 -10.969 1.00 28.97 ? 92 ALA D N 1 ATOM 5163 C CA . ALA D 4 93 ? 14.760 46.595 -10.708 1.00 29.05 ? 92 ALA D CA 1 ATOM 5164 C C . ALA D 4 93 ? 15.551 45.877 -9.631 1.00 28.67 ? 92 ALA D C 1 ATOM 5165 O O . ALA D 4 93 ? 16.677 46.259 -9.311 1.00 29.23 ? 92 ALA D O 1 ATOM 5166 C CB . ALA D 4 93 ? 14.710 45.751 -11.993 1.00 27.72 ? 92 ALA D CB 1 ATOM 5167 N N . SER D 4 94 ? 14.937 44.836 -9.072 1.00 28.81 ? 93 SER D N 1 ATOM 5168 C CA . SER D 4 94 ? 15.590 43.984 -8.082 1.00 28.78 ? 93 SER D CA 1 ATOM 5169 C C . SER D 4 94 ? 15.344 42.504 -8.369 1.00 28.17 ? 93 SER D C 1 ATOM 5170 O O . SER D 4 94 ? 14.405 42.149 -9.104 1.00 26.60 ? 93 SER D O 1 ATOM 5171 C CB . SER D 4 94 ? 15.122 44.343 -6.658 1.00 28.80 ? 93 SER D CB 1 ATOM 5172 O OG . SER D 4 94 ? 13.929 43.661 -6.305 1.00 28.16 ? 93 SER D OG 1 ATOM 5173 N N . GLY D 4 95 ? 16.190 41.654 -7.783 1.00 28.40 ? 94 GLY D N 1 ATOM 5174 C CA . GLY D 4 95 ? 16.028 40.201 -7.864 1.00 30.13 ? 94 GLY D CA 1 ATOM 5175 C C . GLY D 4 95 ? 16.890 39.452 -6.871 1.00 32.09 ? 94 GLY D C 1 ATOM 5176 O O . GLY D 4 95 ? 17.818 40.016 -6.280 1.00 33.99 ? 94 GLY D O 1 ATOM 5177 N N . ASP D 4 96 ? 16.582 38.179 -6.657 1.00 34.01 ? 95 ASP D N 1 ATOM 5178 C CA . ASP D 4 96 ? 17.483 37.338 -5.869 1.00 34.93 ? 95 ASP D CA 1 ATOM 5179 C C . ASP D 4 96 ? 18.341 36.517 -6.817 1.00 34.46 ? 95 ASP D C 1 ATOM 5180 O O . ASP D 4 96 ? 18.663 36.983 -7.901 1.00 34.54 ? 95 ASP D O 1 ATOM 5181 C CB . ASP D 4 96 ? 16.739 36.467 -4.849 1.00 36.19 ? 95 ASP D CB 1 ATOM 5182 C CG . ASP D 4 96 ? 15.593 35.684 -5.455 1.00 39.70 ? 95 ASP D CG 1 ATOM 5183 O OD1 . ASP D 4 96 ? 15.599 35.370 -6.672 1.00 43.82 ? 95 ASP D OD1 1 ATOM 5184 O OD2 . ASP D 4 96 ? 14.673 35.361 -4.684 1.00 42.40 ? 95 ASP D OD2 1 ATOM 5185 N N . GLU D 4 97 ? 18.705 35.304 -6.415 1.00 35.27 ? 96 GLU D N 1 ATOM 5186 C CA . GLU D 4 97 ? 19.582 34.456 -7.224 1.00 35.21 ? 96 GLU D CA 1 ATOM 5187 C C . GLU D 4 97 ? 18.950 34.009 -8.549 1.00 33.59 ? 96 GLU D C 1 ATOM 5188 O O . GLU D 4 97 ? 19.676 33.721 -9.502 1.00 33.09 ? 96 GLU D O 1 ATOM 5189 C CB . GLU D 4 97 ? 20.095 33.251 -6.414 1.00 37.18 ? 96 GLU D CB 1 ATOM 5190 C CG . GLU D 4 97 ? 19.010 32.381 -5.748 1.00 40.31 ? 96 GLU D CG 1 ATOM 5191 C CD . GLU D 4 97 ? 18.475 32.937 -4.425 1.00 43.36 ? 96 GLU D CD 1 ATOM 5192 O OE1 . GLU D 4 97 ? 18.867 34.061 -4.013 1.00 43.57 ? 96 GLU D OE1 1 ATOM 5193 O OE2 . GLU D 4 97 ? 17.651 32.232 -3.795 1.00 45.13 ? 96 GLU D OE2 1 ATOM 5194 N N . GLY D 4 98 ? 17.616 33.966 -8.600 1.00 30.92 ? 97 GLY D N 1 ATOM 5195 C CA . GLY D 4 98 ? 16.884 33.502 -9.782 1.00 31.42 ? 97 GLY D CA 1 ATOM 5196 C C . GLY D 4 98 ? 16.933 34.447 -10.975 1.00 30.65 ? 97 GLY D C 1 ATOM 5197 O O . GLY D 4 98 ? 17.620 35.475 -10.937 1.00 28.66 ? 97 GLY D O 1 ATOM 5198 N N . TYR D 4 99 ? 16.204 34.115 -12.041 1.00 29.83 ? 98 TYR D N 1 ATOM 5199 C CA . TYR D 4 99 ? 16.275 34.954 -13.257 1.00 30.29 ? 98 TYR D CA 1 ATOM 5200 C C . TYR D 4 99 ? 15.361 36.201 -13.295 1.00 29.65 ? 98 TYR D C 1 ATOM 5201 O O . TYR D 4 99 ? 15.727 37.200 -13.912 1.00 29.31 ? 98 TYR D O 1 ATOM 5202 C CB . TYR D 4 99 ? 16.199 34.133 -14.561 1.00 28.58 ? 98 TYR D CB 1 ATOM 5203 C CG . TYR D 4 99 ? 14.939 33.323 -14.744 1.00 28.55 ? 98 TYR D CG 1 ATOM 5204 C CD1 . TYR D 4 99 ? 13.769 33.923 -15.190 1.00 28.55 ? 98 TYR D CD1 1 ATOM 5205 C CD2 . TYR D 4 99 ? 14.925 31.949 -14.507 1.00 28.38 ? 98 TYR D CD2 1 ATOM 5206 C CE1 . TYR D 4 99 ? 12.616 33.190 -15.377 1.00 28.67 ? 98 TYR D CE1 1 ATOM 5207 C CE2 . TYR D 4 99 ? 13.769 31.206 -14.686 1.00 28.63 ? 98 TYR D CE2 1 ATOM 5208 C CZ . TYR D 4 99 ? 12.617 31.841 -15.122 1.00 28.83 ? 98 TYR D CZ 1 ATOM 5209 O OH . TYR D 4 99 ? 11.449 31.142 -15.303 1.00 29.62 ? 98 TYR D OH 1 ATOM 5210 N N . THR D 4 100 ? 14.207 36.136 -12.625 1.00 28.92 ? 99 THR D N 1 ATOM 5211 C CA . THR D 4 100 ? 13.238 37.243 -12.580 1.00 28.04 ? 99 THR D CA 1 ATOM 5212 C C . THR D 4 100 ? 13.797 38.528 -11.978 1.00 27.89 ? 99 THR D C 1 ATOM 5213 O O . THR D 4 100 ? 14.377 38.529 -10.889 1.00 28.48 ? 99 THR D O 1 ATOM 5214 C CB . THR D 4 100 ? 11.972 36.879 -11.769 1.00 28.14 ? 99 THR D CB 1 ATOM 5215 O OG1 . THR D 4 100 ? 11.454 35.620 -12.208 1.00 29.66 ? 99 THR D OG1 1 ATOM 5216 C CG2 . THR D 4 100 ? 10.901 37.927 -11.953 1.00 27.68 ? 99 THR D CG2 1 ATOM 5217 N N . GLN D 4 101 ? 13.616 39.626 -12.701 1.00 27.51 ? 100 GLN D N 1 ATOM 5218 C CA . GLN D 4 101 ? 13.842 40.948 -12.146 1.00 26.64 ? 100 GLN D CA 1 ATOM 5219 C C . GLN D 4 101 ? 12.471 41.572 -11.999 1.00 27.62 ? 100 GLN D C 1 ATOM 5220 O O . GLN D 4 101 ? 11.620 41.399 -12.866 1.00 27.70 ? 100 GLN D O 1 ATOM 5221 C CB . GLN D 4 101 ? 14.742 41.776 -13.048 1.00 25.31 ? 100 GLN D CB 1 ATOM 5222 C CG . GLN D 4 101 ? 16.125 41.184 -13.160 1.00 24.34 ? 100 GLN D CG 1 ATOM 5223 C CD . GLN D 4 101 ? 17.112 42.058 -13.886 1.00 23.98 ? 100 GLN D CD 1 ATOM 5224 O OE1 . GLN D 4 101 ? 16.773 43.092 -14.442 1.00 24.64 ? 100 GLN D OE1 1 ATOM 5225 N NE2 . GLN D 4 101 ? 18.350 41.633 -13.894 1.00 24.54 ? 100 GLN D NE2 1 ATOM 5226 N N . TYR D 4 102 ? 12.253 42.244 -10.870 1.00 28.52 ? 101 TYR D N 1 ATOM 5227 C CA . TYR D 4 102 ? 10.983 42.869 -10.554 1.00 28.54 ? 101 TYR D CA 1 ATOM 5228 C C . TYR D 4 102 ? 11.193 44.357 -10.724 1.00 29.82 ? 101 TYR D C 1 ATOM 5229 O O . TYR D 4 102 ? 12.067 44.947 -10.050 1.00 30.51 ? 101 TYR D O 1 ATOM 5230 C CB . TYR D 4 102 ? 10.576 42.537 -9.118 1.00 30.04 ? 101 TYR D CB 1 ATOM 5231 C CG . TYR D 4 102 ? 10.485 41.036 -8.855 1.00 31.61 ? 101 TYR D CG 1 ATOM 5232 C CD1 . TYR D 4 102 ? 9.288 40.327 -9.081 1.00 29.80 ? 101 TYR D CD1 1 ATOM 5233 C CD2 . TYR D 4 102 ? 11.611 40.318 -8.394 1.00 30.59 ? 101 TYR D CD2 1 ATOM 5234 C CE1 . TYR D 4 102 ? 9.217 38.946 -8.839 1.00 30.25 ? 101 TYR D CE1 1 ATOM 5235 C CE2 . TYR D 4 102 ? 11.552 38.956 -8.159 1.00 29.71 ? 101 TYR D CE2 1 ATOM 5236 C CZ . TYR D 4 102 ? 10.362 38.267 -8.376 1.00 30.82 ? 101 TYR D CZ 1 ATOM 5237 O OH . TYR D 4 102 ? 10.338 36.899 -8.138 1.00 31.30 ? 101 TYR D OH 1 ATOM 5238 N N . PHE D 4 103 ? 10.416 44.957 -11.632 1.00 27.49 ? 102 PHE D N 1 ATOM 5239 C CA . PHE D 4 103 ? 10.648 46.336 -12.041 1.00 26.88 ? 102 PHE D CA 1 ATOM 5240 C C . PHE D 4 103 ? 9.871 47.378 -11.247 1.00 27.70 ? 102 PHE D C 1 ATOM 5241 O O . PHE D 4 103 ? 8.755 47.133 -10.823 1.00 29.03 ? 102 PHE D O 1 ATOM 5242 C CB . PHE D 4 103 ? 10.366 46.491 -13.527 1.00 25.79 ? 102 PHE D CB 1 ATOM 5243 C CG . PHE D 4 103 ? 11.400 45.852 -14.401 1.00 25.30 ? 102 PHE D CG 1 ATOM 5244 C CD1 . PHE D 4 103 ? 11.237 44.539 -14.849 1.00 24.27 ? 102 PHE D CD1 1 ATOM 5245 C CD2 . PHE D 4 103 ? 12.559 46.556 -14.763 1.00 24.57 ? 102 PHE D CD2 1 ATOM 5246 C CE1 . PHE D 4 103 ? 12.201 43.945 -15.649 1.00 23.21 ? 102 PHE D CE1 1 ATOM 5247 C CE2 . PHE D 4 103 ? 13.535 45.966 -15.567 1.00 23.33 ? 102 PHE D CE2 1 ATOM 5248 C CZ . PHE D 4 103 ? 13.355 44.663 -16.010 1.00 23.49 ? 102 PHE D CZ 1 ATOM 5249 N N . GLY D 4 104 ? 10.481 48.545 -11.049 1.00 28.63 ? 103 GLY D N 1 ATOM 5250 C CA . GLY D 4 104 ? 9.808 49.695 -10.445 1.00 28.15 ? 103 GLY D CA 1 ATOM 5251 C C . GLY D 4 104 ? 8.851 50.337 -11.434 1.00 28.81 ? 103 GLY D C 1 ATOM 5252 O O . GLY D 4 104 ? 8.711 49.849 -12.567 1.00 30.48 ? 103 GLY D O 1 ATOM 5253 N N . PRO D 4 105 ? 8.178 51.431 -11.020 1.00 28.39 ? 104 PRO D N 1 ATOM 5254 C CA . PRO D 4 105 ? 7.142 52.046 -11.856 1.00 27.52 ? 104 PRO D CA 1 ATOM 5255 C C . PRO D 4 105 ? 7.662 53.045 -12.874 1.00 27.15 ? 104 PRO D C 1 ATOM 5256 O O . PRO D 4 105 ? 6.912 53.457 -13.758 1.00 27.42 ? 104 PRO D O 1 ATOM 5257 C CB . PRO D 4 105 ? 6.251 52.749 -10.840 1.00 27.27 ? 104 PRO D CB 1 ATOM 5258 C CG . PRO D 4 105 ? 7.136 53.077 -9.720 1.00 28.10 ? 104 PRO D CG 1 ATOM 5259 C CD . PRO D 4 105 ? 8.233 52.044 -9.681 1.00 28.66 ? 104 PRO D CD 1 ATOM 5260 N N . GLY D 4 106 ? 8.925 53.438 -12.740 1.00 26.84 ? 105 GLY D N 1 ATOM 5261 C CA . GLY D 4 106 ? 9.547 54.387 -13.653 1.00 26.19 ? 105 GLY D CA 1 ATOM 5262 C C . GLY D 4 106 ? 9.704 55.764 -13.054 1.00 26.83 ? 105 GLY D C 1 ATOM 5263 O O . GLY D 4 106 ? 9.014 56.109 -12.098 1.00 27.30 ? 105 GLY D O 1 ATOM 5264 N N . THR D 4 107 ? 10.625 56.540 -13.620 1.00 27.70 ? 106 THR D N 1 ATOM 5265 C CA . THR D 4 107 ? 10.904 57.912 -13.209 1.00 28.44 ? 106 THR D CA 1 ATOM 5266 C C . THR D 4 107 ? 11.226 58.695 -14.462 1.00 30.07 ? 106 THR D C 1 ATOM 5267 O O . THR D 4 107 ? 12.186 58.361 -15.177 1.00 30.14 ? 106 THR D O 1 ATOM 5268 C CB . THR D 4 107 ? 12.139 57.989 -12.283 1.00 28.98 ? 106 THR D CB 1 ATOM 5269 O OG1 . THR D 4 107 ? 11.839 57.376 -11.023 1.00 30.04 ? 106 THR D OG1 1 ATOM 5270 C CG2 . THR D 4 107 ? 12.581 59.443 -12.058 1.00 27.96 ? 106 THR D CG2 1 ATOM 5271 N N . ARG D 4 108 ? 10.436 59.734 -14.728 1.00 30.86 ? 107 ARG D N 1 ATOM 5272 C CA . ARG D 4 108 ? 10.655 60.563 -15.902 1.00 32.15 ? 107 ARG D CA 1 ATOM 5273 C C . ARG D 4 108 ? 11.616 61.682 -15.590 1.00 31.15 ? 107 ARG D C 1 ATOM 5274 O O . ARG D 4 108 ? 11.423 62.424 -14.633 1.00 31.01 ? 107 ARG D O 1 ATOM 5275 C CB . ARG D 4 108 ? 9.354 61.172 -16.388 1.00 35.81 ? 107 ARG D CB 1 ATOM 5276 C CG . ARG D 4 108 ? 8.396 60.202 -16.972 1.00 40.61 ? 107 ARG D CG 1 ATOM 5277 C CD . ARG D 4 108 ? 7.421 60.950 -17.860 1.00 48.33 ? 107 ARG D CD 1 ATOM 5278 N NE . ARG D 4 108 ? 6.055 60.487 -17.641 1.00 50.98 ? 107 ARG D NE 1 ATOM 5279 C CZ . ARG D 4 108 ? 5.499 59.468 -18.279 1.00 53.02 ? 107 ARG D CZ 1 ATOM 5280 N NH1 . ARG D 4 108 ? 6.186 58.793 -19.198 1.00 52.94 ? 107 ARG D NH1 1 ATOM 5281 N NH2 . ARG D 4 108 ? 4.251 59.131 -17.994 1.00 56.19 ? 107 ARG D NH2 1 ATOM 5282 N N . LEU D 4 109 ? 12.648 61.813 -16.409 1.00 30.90 ? 108 LEU D N 1 ATOM 5283 C CA . LEU D 4 109 ? 13.581 62.920 -16.267 1.00 30.51 ? 108 LEU D CA 1 ATOM 5284 C C . LEU D 4 109 ? 13.542 63.770 -17.517 1.00 31.38 ? 108 LEU D C 1 ATOM 5285 O O . LEU D 4 109 ? 13.552 63.252 -18.641 1.00 31.02 ? 108 LEU D O 1 ATOM 5286 C CB . LEU D 4 109 ? 15.006 62.421 -16.016 1.00 29.93 ? 108 LEU D CB 1 ATOM 5287 C CG . LEU D 4 109 ? 16.062 63.470 -15.656 1.00 30.43 ? 108 LEU D CG 1 ATOM 5288 C CD1 . LEU D 4 109 ? 15.727 64.222 -14.359 1.00 30.44 ? 108 LEU D CD1 1 ATOM 5289 C CD2 . LEU D 4 109 ? 17.433 62.816 -15.546 1.00 30.82 ? 108 LEU D CD2 1 ATOM 5290 N N . LEU D 4 110 ? 13.454 65.078 -17.306 1.00 30.77 ? 109 LEU D N 1 ATOM 5291 C CA . LEU D 4 110 ? 13.668 66.038 -18.365 1.00 30.20 ? 109 LEU D CA 1 ATOM 5292 C C . LEU D 4 110 ? 14.765 66.969 -17.891 1.00 30.79 ? 109 LEU D C 1 ATOM 5293 O O . LEU D 4 110 ? 14.665 67.557 -16.810 1.00 29.88 ? 109 LEU D O 1 ATOM 5294 C CB . LEU D 4 110 ? 12.398 66.827 -18.663 1.00 30.26 ? 109 LEU D CB 1 ATOM 5295 C CG . LEU D 4 110 ? 12.529 67.992 -19.653 1.00 30.60 ? 109 LEU D CG 1 ATOM 5296 C CD1 . LEU D 4 110 ? 12.699 67.520 -21.097 1.00 28.83 ? 109 LEU D CD1 1 ATOM 5297 C CD2 . LEU D 4 110 ? 11.315 68.888 -19.526 1.00 30.80 ? 109 LEU D CD2 1 ATOM 5298 N N . VAL D 4 111 ? 15.823 67.075 -18.691 1.00 30.97 ? 110 VAL D N 1 ATOM 5299 C CA . VAL D 4 111 ? 16.924 67.977 -18.394 1.00 30.45 ? 110 VAL D CA 1 ATOM 5300 C C . VAL D 4 111 ? 16.904 69.095 -19.421 1.00 31.48 ? 110 VAL D C 1 ATOM 5301 O O . VAL D 4 111 ? 17.106 68.861 -20.625 1.00 31.71 ? 110 VAL D O 1 ATOM 5302 C CB . VAL D 4 111 ? 18.277 67.249 -18.419 1.00 30.83 ? 110 VAL D CB 1 ATOM 5303 C CG1 . VAL D 4 111 ? 19.409 68.200 -18.032 1.00 31.13 ? 110 VAL D CG1 1 ATOM 5304 C CG2 . VAL D 4 111 ? 18.251 66.020 -17.494 1.00 30.26 ? 110 VAL D CG2 1 ATOM 5305 N N . LEU D 4 112 ? 16.625 70.303 -18.943 1.00 32.23 ? 111 LEU D N 1 ATOM 5306 C CA . LEU D 4 112 ? 16.571 71.488 -19.797 1.00 33.85 ? 111 LEU D CA 1 ATOM 5307 C C . LEU D 4 112 ? 17.894 72.257 -19.777 1.00 36.61 ? 111 LEU D C 1 ATOM 5308 O O . LEU D 4 112 ? 18.660 72.181 -18.804 1.00 37.93 ? 111 LEU D O 1 ATOM 5309 C CB . LEU D 4 112 ? 15.447 72.418 -19.339 1.00 32.17 ? 111 LEU D CB 1 ATOM 5310 C CG . LEU D 4 112 ? 13.990 71.978 -19.416 1.00 30.87 ? 111 LEU D CG 1 ATOM 5311 C CD1 . LEU D 4 112 ? 13.206 72.781 -18.392 1.00 30.82 ? 111 LEU D CD1 1 ATOM 5312 C CD2 . LEU D 4 112 ? 13.423 72.173 -20.802 1.00 29.58 ? 111 LEU D CD2 1 ATOM 5313 N N . GLU D 4 113 ? 18.149 72.996 -20.856 1.00 38.59 ? 112 GLU D N 1 ATOM 5314 C CA . GLU D 4 113 ? 19.292 73.896 -20.936 1.00 40.77 ? 112 GLU D CA 1 ATOM 5315 C C . GLU D 4 113 ? 19.105 75.010 -19.919 1.00 41.48 ? 112 GLU D C 1 ATOM 5316 O O . GLU D 4 113 ? 20.051 75.413 -19.233 1.00 40.09 ? 112 GLU D O 1 ATOM 5317 C CB . GLU D 4 113 ? 19.407 74.513 -22.338 1.00 45.11 ? 112 GLU D CB 1 ATOM 5318 C CG . GLU D 4 113 ? 19.283 73.536 -23.524 1.00 49.19 ? 112 GLU D CG 1 ATOM 5319 C CD . GLU D 4 113 ? 20.540 72.692 -23.764 1.00 52.47 ? 112 GLU D CD 1 ATOM 5320 O OE1 . GLU D 4 113 ? 20.520 71.862 -24.709 1.00 52.77 ? 112 GLU D OE1 1 ATOM 5321 O OE2 . GLU D 4 113 ? 21.541 72.852 -23.017 1.00 52.41 ? 112 GLU D OE2 1 ATOM 5322 N N . ASP D 4 114 ? 17.866 75.494 -19.823 1.00 42.92 ? 113 ASP D N 1 ATOM 5323 C CA . ASP D 4 114 ? 17.549 76.671 -19.023 1.00 42.21 ? 113 ASP D CA 1 ATOM 5324 C C . ASP D 4 114 ? 16.195 76.529 -18.358 1.00 39.35 ? 113 ASP D C 1 ATOM 5325 O O . ASP D 4 114 ? 15.266 75.960 -18.939 1.00 38.60 ? 113 ASP D O 1 ATOM 5326 C CB . ASP D 4 114 ? 17.529 77.908 -19.920 1.00 47.31 ? 113 ASP D CB 1 ATOM 5327 C CG . ASP D 4 114 ? 17.669 79.198 -19.142 1.00 52.89 ? 113 ASP D CG 1 ATOM 5328 O OD1 . ASP D 4 114 ? 17.704 79.177 -17.889 1.00 57.14 ? 113 ASP D OD1 1 ATOM 5329 O OD2 . ASP D 4 114 ? 17.761 80.250 -19.794 1.00 59.87 ? 113 ASP D OD2 1 ATOM 5330 N N . LEU D 4 115 ? 16.085 77.075 -17.152 1.00 34.72 ? 114 LEU D N 1 ATOM 5331 C CA . LEU D 4 115 ? 14.830 77.068 -16.412 1.00 32.77 ? 114 LEU D CA 1 ATOM 5332 C C . LEU D 4 115 ? 13.963 78.341 -16.585 1.00 33.74 ? 114 LEU D C 1 ATOM 5333 O O . LEU D 4 115 ? 12.890 78.436 -16.000 1.00 33.62 ? 114 LEU D O 1 ATOM 5334 C CB . LEU D 4 115 ? 15.098 76.769 -14.927 1.00 29.65 ? 114 LEU D CB 1 ATOM 5335 C CG . LEU D 4 115 ? 15.819 75.450 -14.585 1.00 28.36 ? 114 LEU D CG 1 ATOM 5336 C CD1 . LEU D 4 115 ? 16.042 75.289 -13.082 1.00 27.13 ? 114 LEU D CD1 1 ATOM 5337 C CD2 . LEU D 4 115 ? 15.124 74.221 -15.144 1.00 27.27 ? 114 LEU D CD2 1 ATOM 5338 N N . ARG D 4 116 ? 14.404 79.290 -17.411 1.00 35.78 ? 115 ARG D N 1 ATOM 5339 C CA . ARG D 4 116 ? 13.718 80.595 -17.564 1.00 37.95 ? 115 ARG D CA 1 ATOM 5340 C C . ARG D 4 116 ? 12.222 80.530 -17.943 1.00 38.61 ? 115 ARG D C 1 ATOM 5341 O O . ARG D 4 116 ? 11.473 81.469 -17.656 1.00 40.12 ? 115 ARG D O 1 ATOM 5342 C CB . ARG D 4 116 ? 14.465 81.509 -18.553 1.00 37.65 ? 115 ARG D CB 1 ATOM 5343 C CG . ARG D 4 116 ? 14.305 81.078 -20.002 1.00 40.25 ? 115 ARG D CG 1 ATOM 5344 C CD . ARG D 4 116 ? 15.231 81.791 -20.983 1.00 41.08 ? 115 ARG D CD 1 ATOM 5345 N NE . ARG D 4 116 ? 15.533 80.895 -22.104 1.00 40.62 ? 115 ARG D NE 1 ATOM 5346 C CZ . ARG D 4 116 ? 14.888 80.908 -23.266 1.00 41.28 ? 115 ARG D CZ 1 ATOM 5347 N NH1 . ARG D 4 116 ? 13.917 81.789 -23.473 1.00 41.95 ? 115 ARG D NH1 1 ATOM 5348 N NH2 . ARG D 4 116 ? 15.211 80.044 -24.223 1.00 40.01 ? 115 ARG D NH2 1 ATOM 5349 N N . ASN D 4 117 ? 11.786 79.441 -18.574 1.00 37.36 ? 116 ASN D N 1 ATOM 5350 C CA . ASN D 4 117 ? 10.397 79.361 -19.040 1.00 38.31 ? 116 ASN D CA 1 ATOM 5351 C C . ASN D 4 117 ? 9.441 78.558 -18.156 1.00 36.84 ? 116 ASN D C 1 ATOM 5352 O O . ASN D 4 117 ? 8.240 78.514 -18.428 1.00 38.20 ? 116 ASN D O 1 ATOM 5353 C CB . ASN D 4 117 ? 10.324 78.876 -20.501 1.00 40.75 ? 116 ASN D CB 1 ATOM 5354 C CG . ASN D 4 117 ? 10.874 79.909 -21.501 1.00 44.62 ? 116 ASN D CG 1 ATOM 5355 O OD1 . ASN D 4 117 ? 10.605 81.114 -21.391 1.00 44.70 ? 116 ASN D OD1 1 ATOM 5356 N ND2 . ASN D 4 117 ? 11.651 79.435 -22.478 1.00 43.79 ? 116 ASN D ND2 1 ATOM 5357 N N . VAL D 4 118 ? 9.959 77.930 -17.105 1.00 34.01 ? 117 VAL D N 1 ATOM 5358 C CA . VAL D 4 118 ? 9.127 77.081 -16.248 1.00 31.73 ? 117 VAL D CA 1 ATOM 5359 C C . VAL D 4 118 ? 7.957 77.890 -15.657 1.00 30.95 ? 117 VAL D C 1 ATOM 5360 O O . VAL D 4 118 ? 8.150 78.980 -15.120 1.00 31.83 ? 117 VAL D O 1 ATOM 5361 C CB . VAL D 4 118 ? 9.961 76.378 -15.144 1.00 31.32 ? 117 VAL D CB 1 ATOM 5362 C CG1 . VAL D 4 118 ? 9.094 75.456 -14.312 1.00 30.71 ? 117 VAL D CG1 1 ATOM 5363 C CG2 . VAL D 4 118 ? 11.111 75.589 -15.761 1.00 31.02 ? 117 VAL D CG2 1 ATOM 5364 N N . THR D 4 119 ? 6.745 77.356 -15.790 1.00 29.18 ? 118 THR D N 1 ATOM 5365 C CA . THR D 4 119 ? 5.526 78.044 -15.357 1.00 27.35 ? 118 THR D CA 1 ATOM 5366 C C . THR D 4 119 ? 4.476 77.020 -14.921 1.00 25.44 ? 118 THR D C 1 ATOM 5367 O O . THR D 4 119 ? 4.191 76.082 -15.672 1.00 25.18 ? 118 THR D O 1 ATOM 5368 C CB . THR D 4 119 ? 4.913 78.908 -16.510 1.00 26.76 ? 118 THR D CB 1 ATOM 5369 O OG1 . THR D 4 119 ? 5.945 79.635 -17.172 1.00 27.70 ? 118 THR D OG1 1 ATOM 5370 C CG2 . THR D 4 119 ? 3.882 79.892 -15.982 1.00 25.87 ? 118 THR D CG2 1 ATOM 5371 N N . PRO D 4 120 ? 3.870 77.215 -13.733 1.00 23.81 ? 119 PRO D N 1 ATOM 5372 C CA . PRO D 4 120 ? 2.776 76.338 -13.335 1.00 23.90 ? 119 PRO D CA 1 ATOM 5373 C C . PRO D 4 120 ? 1.503 76.625 -14.155 1.00 23.49 ? 119 PRO D C 1 ATOM 5374 O O . PRO D 4 120 ? 1.374 77.717 -14.716 1.00 23.12 ? 119 PRO D O 1 ATOM 5375 C CB . PRO D 4 120 ? 2.575 76.685 -11.849 1.00 23.37 ? 119 PRO D CB 1 ATOM 5376 C CG . PRO D 4 120 ? 2.950 78.104 -11.758 1.00 23.32 ? 119 PRO D CG 1 ATOM 5377 C CD . PRO D 4 120 ? 4.071 78.306 -12.760 1.00 23.90 ? 119 PRO D CD 1 ATOM 5378 N N . PRO D 4 121 ? 0.574 75.649 -14.232 1.00 23.45 ? 120 PRO D N 1 ATOM 5379 C CA . PRO D 4 121 ? -0.655 75.839 -14.997 1.00 23.91 ? 120 PRO D CA 1 ATOM 5380 C C . PRO D 4 121 ? -1.760 76.606 -14.253 1.00 24.90 ? 120 PRO D C 1 ATOM 5381 O O . PRO D 4 121 ? -1.733 76.700 -13.025 1.00 23.85 ? 120 PRO D O 1 ATOM 5382 C CB . PRO D 4 121 ? -1.114 74.401 -15.262 1.00 23.40 ? 120 PRO D CB 1 ATOM 5383 C CG . PRO D 4 121 ? -0.628 73.633 -14.070 1.00 22.76 ? 120 PRO D CG 1 ATOM 5384 C CD . PRO D 4 121 ? 0.672 74.279 -13.678 1.00 23.19 ? 120 PRO D CD 1 ATOM 5385 N N . LYS D 4 122 ? -2.698 77.168 -15.020 1.00 26.87 ? 121 LYS D N 1 ATOM 5386 C CA . LYS D 4 122 ? -4.016 77.550 -14.519 1.00 28.21 ? 121 LYS D CA 1 ATOM 5387 C C . LYS D 4 122 ? -4.880 76.324 -14.704 1.00 29.47 ? 121 LYS D C 1 ATOM 5388 O O . LYS D 4 122 ? -4.724 75.589 -15.676 1.00 32.25 ? 121 LYS D O 1 ATOM 5389 C CB . LYS D 4 122 ? -4.623 78.705 -15.334 1.00 29.60 ? 121 LYS D CB 1 ATOM 5390 C CG . LYS D 4 122 ? -3.912 80.048 -15.187 1.00 32.74 ? 121 LYS D CG 1 ATOM 5391 C CD . LYS D 4 122 ? -3.541 80.320 -13.727 1.00 35.11 ? 121 LYS D CD 1 ATOM 5392 C CE . LYS D 4 122 ? -2.617 81.510 -13.587 1.00 37.88 ? 121 LYS D CE 1 ATOM 5393 N NZ . LYS D 4 122 ? -3.386 82.785 -13.611 1.00 39.08 ? 121 LYS D NZ 1 ATOM 5394 N N . VAL D 4 123 ? -5.799 76.090 -13.788 1.00 29.12 ? 122 VAL D N 1 ATOM 5395 C CA . VAL D 4 123 ? -6.682 74.954 -13.932 1.00 27.93 ? 122 VAL D CA 1 ATOM 5396 C C . VAL D 4 123 ? -8.103 75.466 -13.844 1.00 29.12 ? 122 VAL D C 1 ATOM 5397 O O . VAL D 4 123 ? -8.454 76.164 -12.907 1.00 30.81 ? 122 VAL D O 1 ATOM 5398 C CB . VAL D 4 123 ? -6.418 73.905 -12.834 1.00 26.56 ? 122 VAL D CB 1 ATOM 5399 C CG1 . VAL D 4 123 ? -7.366 72.724 -12.968 1.00 25.78 ? 122 VAL D CG1 1 ATOM 5400 C CG2 . VAL D 4 123 ? -4.980 73.432 -12.907 1.00 25.95 ? 122 VAL D CG2 1 ATOM 5401 N N . SER D 4 124 ? -8.917 75.136 -14.834 1.00 29.74 ? 123 SER D N 1 ATOM 5402 C CA . SER D 4 124 ? -10.331 75.480 -14.801 1.00 28.85 ? 123 SER D CA 1 ATOM 5403 C C . SER D 4 124 ? -11.118 74.197 -14.864 1.00 28.36 ? 123 SER D C 1 ATOM 5404 O O . SER D 4 124 ? -10.675 73.244 -15.506 1.00 28.98 ? 123 SER D O 1 ATOM 5405 C CB . SER D 4 124 ? -10.703 76.366 -15.986 1.00 29.18 ? 123 SER D CB 1 ATOM 5406 O OG . SER D 4 124 ? -10.096 77.639 -15.891 1.00 30.13 ? 123 SER D OG 1 ATOM 5407 N N . LEU D 4 125 ? -12.269 74.172 -14.189 1.00 27.74 ? 124 LEU D N 1 ATOM 5408 C CA . LEU D 4 125 ? -13.222 73.071 -14.290 1.00 26.86 ? 124 LEU D CA 1 ATOM 5409 C C . LEU D 4 125 ? -14.496 73.585 -14.935 1.00 27.34 ? 124 LEU D C 1 ATOM 5410 O O . LEU D 4 125 ? -15.016 74.619 -14.543 1.00 27.32 ? 124 LEU D O 1 ATOM 5411 C CB . LEU D 4 125 ? -13.532 72.486 -12.918 1.00 26.42 ? 124 LEU D CB 1 ATOM 5412 C CG . LEU D 4 125 ? -14.645 71.442 -12.804 1.00 26.89 ? 124 LEU D CG 1 ATOM 5413 C CD1 . LEU D 4 125 ? -14.337 70.222 -13.634 1.00 27.28 ? 124 LEU D CD1 1 ATOM 5414 C CD2 . LEU D 4 125 ? -14.807 71.036 -11.364 1.00 27.75 ? 124 LEU D CD2 1 ATOM 5415 N N . PHE D 4 126 ? -14.986 72.859 -15.932 1.00 28.25 ? 125 PHE D N 1 ATOM 5416 C CA . PHE D 4 126 ? -16.170 73.266 -16.666 1.00 28.71 ? 125 PHE D CA 1 ATOM 5417 C C . PHE D 4 126 ? -17.331 72.349 -16.347 1.00 30.62 ? 125 PHE D C 1 ATOM 5418 O O . PHE D 4 126 ? -17.210 71.128 -16.415 1.00 31.08 ? 125 PHE D O 1 ATOM 5419 C CB . PHE D 4 126 ? -15.864 73.336 -18.157 1.00 27.86 ? 125 PHE D CB 1 ATOM 5420 C CG . PHE D 4 126 ? -14.873 74.401 -18.495 1.00 27.49 ? 125 PHE D CG 1 ATOM 5421 C CD1 . PHE D 4 126 ? -13.518 74.179 -18.332 1.00 27.33 ? 125 PHE D CD1 1 ATOM 5422 C CD2 . PHE D 4 126 ? -15.292 75.645 -18.914 1.00 27.66 ? 125 PHE D CD2 1 ATOM 5423 C CE1 . PHE D 4 126 ? -12.593 75.161 -18.613 1.00 26.97 ? 125 PHE D CE1 1 ATOM 5424 C CE2 . PHE D 4 126 ? -14.367 76.630 -19.189 1.00 28.86 ? 125 PHE D CE2 1 ATOM 5425 C CZ . PHE D 4 126 ? -13.006 76.377 -19.042 1.00 27.55 ? 125 PHE D CZ 1 ATOM 5426 N N . GLU D 4 127 ? -18.447 72.959 -15.967 1.00 33.01 ? 126 GLU D N 1 ATOM 5427 C CA . GLU D 4 127 ? -19.592 72.236 -15.446 1.00 36.19 ? 126 GLU D CA 1 ATOM 5428 C C . GLU D 4 127 ? -20.492 71.685 -16.558 1.00 38.22 ? 126 GLU D C 1 ATOM 5429 O O . GLU D 4 127 ? -20.694 72.344 -17.593 1.00 40.16 ? 126 GLU D O 1 ATOM 5430 C CB . GLU D 4 127 ? -20.384 73.130 -14.487 1.00 38.78 ? 126 GLU D CB 1 ATOM 5431 C CG . GLU D 4 127 ? -19.575 73.629 -13.285 1.00 42.24 ? 126 GLU D CG 1 ATOM 5432 C CD . GLU D 4 127 ? -20.440 74.077 -12.108 1.00 46.28 ? 126 GLU D CD 1 ATOM 5433 O OE1 . GLU D 4 127 ? -21.685 73.939 -12.157 1.00 47.15 ? 126 GLU D OE1 1 ATOM 5434 O OE2 . GLU D 4 127 ? -19.868 74.571 -11.116 1.00 49.48 ? 126 GLU D OE2 1 ATOM 5435 N N . PRO D 4 128 ? -21.047 70.478 -16.339 1.00 37.95 ? 127 PRO D N 1 ATOM 5436 C CA . PRO D 4 128 ? -21.899 69.767 -17.284 1.00 38.50 ? 127 PRO D CA 1 ATOM 5437 C C . PRO D 4 128 ? -23.025 70.628 -17.860 1.00 40.17 ? 127 PRO D C 1 ATOM 5438 O O . PRO D 4 128 ? -23.671 71.396 -17.128 1.00 38.69 ? 127 PRO D O 1 ATOM 5439 C CB . PRO D 4 128 ? -22.498 68.652 -16.429 1.00 38.52 ? 127 PRO D CB 1 ATOM 5440 C CG . PRO D 4 128 ? -21.493 68.412 -15.374 1.00 38.36 ? 127 PRO D CG 1 ATOM 5441 C CD . PRO D 4 128 ? -20.916 69.744 -15.067 1.00 38.06 ? 127 PRO D CD 1 ATOM 5442 N N . SER D 4 129 ? -23.243 70.488 -19.167 1.00 40.99 ? 128 SER D N 1 ATOM 5443 C CA . SER D 4 129 ? -24.308 71.184 -19.875 1.00 40.76 ? 128 SER D CA 1 ATOM 5444 C C . SER D 4 129 ? -25.679 70.579 -19.578 1.00 41.83 ? 128 SER D C 1 ATOM 5445 O O . SER D 4 129 ? -25.846 69.356 -19.621 1.00 41.43 ? 128 SER D O 1 ATOM 5446 C CB . SER D 4 129 ? -24.040 71.129 -21.372 1.00 41.47 ? 128 SER D CB 1 ATOM 5447 O OG . SER D 4 129 ? -25.222 71.395 -22.101 1.00 43.97 ? 128 SER D OG 1 ATOM 5448 N N . LYS D 4 130 ? -26.652 71.452 -19.292 1.00 42.78 ? 129 LYS D N 1 ATOM 5449 C CA . LYS D 4 130 ? -28.058 71.071 -19.031 1.00 42.16 ? 129 LYS D CA 1 ATOM 5450 C C . LYS D 4 130 ? -28.676 70.349 -20.232 1.00 40.88 ? 129 LYS D C 1 ATOM 5451 O O . LYS D 4 130 ? -29.527 69.465 -20.077 1.00 39.72 ? 129 LYS D O 1 ATOM 5452 C CB . LYS D 4 130 ? -28.899 72.313 -18.669 1.00 40.43 ? 129 LYS D CB 1 ATOM 5453 N N . ALA D 4 131 ? -28.234 70.747 -21.423 1.00 39.99 ? 130 ALA D N 1 ATOM 5454 C CA . ALA D 4 131 ? -28.628 70.104 -22.657 1.00 41.26 ? 130 ALA D CA 1 ATOM 5455 C C . ALA D 4 131 ? -28.121 68.666 -22.696 1.00 43.70 ? 130 ALA D C 1 ATOM 5456 O O . ALA D 4 131 ? -28.891 67.746 -22.984 1.00 46.54 ? 130 ALA D O 1 ATOM 5457 C CB . ALA D 4 131 ? -28.114 70.891 -23.843 1.00 41.30 ? 130 ALA D CB 1 ATOM 5458 N N . GLU D 4 132 ? -26.839 68.473 -22.388 1.00 44.19 ? 131 GLU D N 1 ATOM 5459 C CA . GLU D 4 132 ? -26.253 67.134 -22.340 1.00 44.82 ? 131 GLU D CA 1 ATOM 5460 C C . GLU D 4 132 ? -27.017 66.216 -21.374 1.00 45.28 ? 131 GLU D C 1 ATOM 5461 O O . GLU D 4 132 ? -27.343 65.068 -21.712 1.00 46.13 ? 131 GLU D O 1 ATOM 5462 C CB . GLU D 4 132 ? -24.766 67.197 -21.972 1.00 44.50 ? 131 GLU D CB 1 ATOM 5463 C CG . GLU D 4 132 ? -24.060 65.839 -22.039 1.00 45.17 ? 131 GLU D CG 1 ATOM 5464 C CD . GLU D 4 132 ? -22.737 65.771 -21.265 1.00 46.38 ? 131 GLU D CD 1 ATOM 5465 O OE1 . GLU D 4 132 ? -22.346 66.742 -20.572 1.00 45.66 ? 131 GLU D OE1 1 ATOM 5466 O OE2 . GLU D 4 132 ? -22.083 64.714 -21.358 1.00 45.75 ? 131 GLU D OE2 1 ATOM 5467 N N . ILE D 4 133 ? -27.313 66.735 -20.187 1.00 43.14 ? 132 ILE D N 1 ATOM 5468 C CA . ILE D 4 133 ? -28.005 65.977 -19.150 1.00 42.93 ? 132 ILE D CA 1 ATOM 5469 C C . ILE D 4 133 ? -29.358 65.477 -19.643 1.00 43.39 ? 132 ILE D C 1 ATOM 5470 O O . ILE D 4 133 ? -29.682 64.306 -19.479 1.00 41.96 ? 132 ILE D O 1 ATOM 5471 C CB . ILE D 4 133 ? -28.144 66.817 -17.861 1.00 43.28 ? 132 ILE D CB 1 ATOM 5472 C CG1 . ILE D 4 133 ? -26.778 66.906 -17.167 1.00 44.45 ? 132 ILE D CG1 1 ATOM 5473 C CG2 . ILE D 4 133 ? -29.186 66.230 -16.928 1.00 40.91 ? 132 ILE D CG2 1 ATOM 5474 C CD1 . ILE D 4 133 ? -26.621 68.065 -16.189 1.00 45.55 ? 132 ILE D CD1 1 ATOM 5475 N N . SER D 4 134 ? -30.122 66.367 -20.275 1.00 45.30 ? 133 SER D N 1 ATOM 5476 C CA . SER D 4 134 ? -31.455 66.044 -20.782 1.00 45.59 ? 133 SER D CA 1 ATOM 5477 C C . SER D 4 134 ? -31.446 65.146 -22.021 1.00 45.31 ? 133 SER D C 1 ATOM 5478 O O . SER D 4 134 ? -32.390 64.392 -22.233 1.00 46.01 ? 133 SER D O 1 ATOM 5479 C CB . SER D 4 134 ? -32.231 67.324 -21.083 1.00 47.28 ? 133 SER D CB 1 ATOM 5480 O OG . SER D 4 134 ? -31.598 68.049 -22.123 1.00 50.45 ? 133 SER D OG 1 ATOM 5481 N N . HIS D 4 135 ? -30.389 65.228 -22.829 1.00 45.07 ? 134 HIS D N 1 ATOM 5482 C CA . HIS D 4 135 ? -30.301 64.475 -24.088 1.00 44.31 ? 134 HIS D CA 1 ATOM 5483 C C . HIS D 4 135 ? -29.768 63.067 -23.934 1.00 44.50 ? 134 HIS D C 1 ATOM 5484 O O . HIS D 4 135 ? -30.075 62.184 -24.744 1.00 42.98 ? 134 HIS D O 1 ATOM 5485 C CB . HIS D 4 135 ? -29.456 65.250 -25.092 1.00 45.49 ? 134 HIS D CB 1 ATOM 5486 C CG . HIS D 4 135 ? -29.596 64.771 -26.526 1.00 49.09 ? 134 HIS D CG 1 ATOM 5487 N ND1 . HIS D 4 135 ? -30.630 65.128 -27.314 1.00 49.72 ? 134 HIS D ND1 1 ATOM 5488 C CD2 . HIS D 4 135 ? -28.768 63.959 -27.308 1.00 49.15 ? 134 HIS D CD2 1 ATOM 5489 C CE1 . HIS D 4 135 ? -30.483 64.563 -28.529 1.00 50.09 ? 134 HIS D CE1 1 ATOM 5490 N NE2 . HIS D 4 135 ? -29.342 63.848 -28.523 1.00 49.31 ? 134 HIS D NE2 1 ATOM 5491 N N . THR D 4 136 ? -28.971 62.838 -22.891 1.00 44.79 ? 135 THR D N 1 ATOM 5492 C CA . THR D 4 136 ? -28.199 61.598 -22.766 1.00 42.84 ? 135 THR D CA 1 ATOM 5493 C C . THR D 4 136 ? -28.355 60.937 -21.410 1.00 42.44 ? 135 THR D C 1 ATOM 5494 O O . THR D 4 136 ? -27.972 59.777 -21.232 1.00 40.94 ? 135 THR D O 1 ATOM 5495 C CB . THR D 4 136 ? -26.701 61.875 -22.935 1.00 44.33 ? 135 THR D CB 1 ATOM 5496 O OG1 . THR D 4 136 ? -26.236 62.659 -21.824 1.00 47.30 ? 135 THR D OG1 1 ATOM 5497 C CG2 . THR D 4 136 ? -26.410 62.608 -24.253 1.00 42.72 ? 135 THR D CG2 1 ATOM 5498 N N . GLN D 4 137 ? -28.901 61.695 -20.460 1.00 43.66 ? 136 GLN D N 1 ATOM 5499 C CA . GLN D 4 137 ? -28.930 61.326 -19.038 1.00 44.19 ? 136 GLN D CA 1 ATOM 5500 C C . GLN D 4 137 ? -27.536 61.101 -18.442 1.00 42.89 ? 136 GLN D C 1 ATOM 5501 O O . GLN D 4 137 ? -27.368 60.375 -17.453 1.00 40.99 ? 136 GLN D O 1 ATOM 5502 C CB . GLN D 4 137 ? -29.886 60.153 -18.763 1.00 46.75 ? 136 GLN D CB 1 ATOM 5503 C CG . GLN D 4 137 ? -31.358 60.546 -18.799 1.00 49.99 ? 136 GLN D CG 1 ATOM 5504 C CD . GLN D 4 137 ? -31.586 62.028 -18.463 1.00 53.79 ? 136 GLN D CD 1 ATOM 5505 O OE1 . GLN D 4 137 ? -31.388 62.470 -17.323 1.00 53.25 ? 136 GLN D OE1 1 ATOM 5506 N NE2 . GLN D 4 137 ? -32.004 62.800 -19.467 1.00 54.94 ? 136 GLN D NE2 1 ATOM 5507 N N . LYS D 4 138 ? -26.550 61.755 -19.055 1.00 41.25 ? 137 LYS D N 1 ATOM 5508 C CA . LYS D 4 138 ? -25.164 61.679 -18.616 1.00 41.68 ? 137 LYS D CA 1 ATOM 5509 C C . LYS D 4 138 ? -24.569 63.081 -18.504 1.00 41.76 ? 137 LYS D C 1 ATOM 5510 O O . LYS D 4 138 ? -24.975 64.006 -19.226 1.00 42.70 ? 137 LYS D O 1 ATOM 5511 C CB . LYS D 4 138 ? -24.342 60.791 -19.559 1.00 43.10 ? 137 LYS D CB 1 ATOM 5512 C CG . LYS D 4 138 ? -24.700 59.300 -19.471 1.00 42.93 ? 137 LYS D CG 1 ATOM 5513 C CD . LYS D 4 138 ? -24.024 58.465 -20.541 1.00 42.68 ? 137 LYS D CD 1 ATOM 5514 C CE . LYS D 4 138 ? -24.713 57.107 -20.685 1.00 44.70 ? 137 LYS D CE 1 ATOM 5515 N NZ . LYS D 4 138 ? -25.905 57.162 -21.601 1.00 42.60 ? 137 LYS D NZ 1 ATOM 5516 N N . ALA D 4 139 ? -23.614 63.235 -17.588 1.00 39.26 ? 138 ALA D N 1 ATOM 5517 C CA . ALA D 4 139 ? -23.019 64.537 -17.298 1.00 37.22 ? 138 ALA D CA 1 ATOM 5518 C C . ALA D 4 139 ? -21.500 64.516 -17.446 1.00 35.62 ? 138 ALA D C 1 ATOM 5519 O O . ALA D 4 139 ? -20.825 63.754 -16.750 1.00 36.68 ? 138 ALA D O 1 ATOM 5520 C CB . ALA D 4 139 ? -23.418 64.991 -15.902 1.00 35.95 ? 138 ALA D CB 1 ATOM 5521 N N . THR D 4 140 ? -20.977 65.351 -18.347 1.00 33.55 ? 139 THR D N 1 ATOM 5522 C CA . THR D 4 140 ? -19.530 65.455 -18.591 1.00 33.96 ? 139 THR D CA 1 ATOM 5523 C C . THR D 4 140 ? -18.926 66.718 -17.999 1.00 32.64 ? 139 THR D C 1 ATOM 5524 O O . THR D 4 140 ? -19.217 67.810 -18.465 1.00 32.35 ? 139 THR D O 1 ATOM 5525 C CB . THR D 4 140 ? -19.176 65.493 -20.104 1.00 34.09 ? 139 THR D CB 1 ATOM 5526 O OG1 . THR D 4 140 ? -19.829 64.424 -20.793 1.00 36.93 ? 139 THR D OG1 1 ATOM 5527 C CG2 . THR D 4 140 ? -17.683 65.369 -20.308 1.00 33.06 ? 139 THR D CG2 1 ATOM 5528 N N . LEU D 4 141 ? -18.073 66.561 -16.993 1.00 32.07 ? 140 LEU D N 1 ATOM 5529 C CA . LEU D 4 141 ? -17.209 67.653 -16.547 1.00 31.49 ? 140 LEU D CA 1 ATOM 5530 C C . LEU D 4 141 ? -15.974 67.679 -17.445 1.00 31.54 ? 140 LEU D C 1 ATOM 5531 O O . LEU D 4 141 ? -15.509 66.630 -17.899 1.00 30.52 ? 140 LEU D O 1 ATOM 5532 C CB . LEU D 4 141 ? -16.778 67.475 -15.086 1.00 30.52 ? 140 LEU D CB 1 ATOM 5533 C CG . LEU D 4 141 ? -17.836 67.343 -13.985 1.00 31.40 ? 140 LEU D CG 1 ATOM 5534 C CD1 . LEU D 4 141 ? -18.575 65.994 -14.008 1.00 31.94 ? 140 LEU D CD1 1 ATOM 5535 C CD2 . LEU D 4 141 ? -17.185 67.539 -12.638 1.00 31.29 ? 140 LEU D CD2 1 ATOM 5536 N N . VAL D 4 142 ? -15.461 68.878 -17.709 1.00 31.45 ? 141 VAL D N 1 ATOM 5537 C CA . VAL D 4 142 ? -14.210 69.044 -18.439 1.00 31.06 ? 141 VAL D CA 1 ATOM 5538 C C . VAL D 4 142 ? -13.220 69.861 -17.617 1.00 31.79 ? 141 VAL D C 1 ATOM 5539 O O . VAL D 4 142 ? -13.567 70.890 -17.031 1.00 31.87 ? 141 VAL D O 1 ATOM 5540 C CB . VAL D 4 142 ? -14.421 69.703 -19.820 1.00 31.16 ? 141 VAL D CB 1 ATOM 5541 C CG1 . VAL D 4 142 ? -13.095 70.170 -20.417 1.00 29.63 ? 141 VAL D CG1 1 ATOM 5542 C CG2 . VAL D 4 142 ? -15.122 68.735 -20.773 1.00 31.95 ? 141 VAL D CG2 1 ATOM 5543 N N . CYS D 4 143 ? -11.984 69.387 -17.578 1.00 31.40 ? 142 CYS D N 1 ATOM 5544 C CA . CYS D 4 143 ? -10.915 70.106 -16.928 1.00 30.59 ? 142 CYS D CA 1 ATOM 5545 C C . CYS D 4 143 ? -9.911 70.638 -17.948 1.00 30.90 ? 142 CYS D C 1 ATOM 5546 O O . CYS D 4 143 ? -9.566 69.948 -18.912 1.00 31.10 ? 142 CYS D O 1 ATOM 5547 C CB . CYS D 4 143 ? -10.212 69.182 -15.966 1.00 31.71 ? 142 CYS D CB 1 ATOM 5548 S SG . CYS D 4 143 ? -8.911 69.988 -15.103 1.00 33.93 ? 142 CYS D SG 1 ATOM 5549 N N . LEU D 4 144 ? -9.421 71.850 -17.708 1.00 29.71 ? 143 LEU D N 1 ATOM 5550 C CA . LEU D 4 144 ? -8.543 72.535 -18.636 1.00 29.41 ? 143 LEU D CA 1 ATOM 5551 C C . LEU D 4 144 ? -7.325 73.055 -17.900 1.00 29.42 ? 143 LEU D C 1 ATOM 5552 O O . LEU D 4 144 ? -7.443 73.892 -17.000 1.00 32.05 ? 143 LEU D O 1 ATOM 5553 C CB . LEU D 4 144 ? -9.299 73.717 -19.230 1.00 30.21 ? 143 LEU D CB 1 ATOM 5554 C CG . LEU D 4 144 ? -8.988 74.247 -20.625 1.00 30.34 ? 143 LEU D CG 1 ATOM 5555 C CD1 . LEU D 4 144 ? -9.280 73.175 -21.650 1.00 30.81 ? 143 LEU D CD1 1 ATOM 5556 C CD2 . LEU D 4 144 ? -9.861 75.461 -20.883 1.00 30.00 ? 143 LEU D CD2 1 ATOM 5557 N N . ALA D 4 145 ? -6.153 72.557 -18.258 1.00 27.45 ? 144 ALA D N 1 ATOM 5558 C CA . ALA D 4 145 ? -4.920 73.065 -17.673 1.00 25.66 ? 144 ALA D CA 1 ATOM 5559 C C . ALA D 4 145 ? -4.185 73.808 -18.770 1.00 25.40 ? 144 ALA D C 1 ATOM 5560 O O . ALA D 4 145 ? -3.971 73.264 -19.853 1.00 25.23 ? 144 ALA D O 1 ATOM 5561 C CB . ALA D 4 145 ? -4.078 71.934 -17.105 1.00 24.19 ? 144 ALA D CB 1 ATOM 5562 N N . THR D 4 146 ? -3.826 75.062 -18.509 1.00 25.36 ? 145 THR D N 1 ATOM 5563 C CA . THR D 4 146 ? -3.241 75.903 -19.549 1.00 25.07 ? 145 THR D CA 1 ATOM 5564 C C . THR D 4 146 ? -2.092 76.739 -19.022 1.00 24.29 ? 145 THR D C 1 ATOM 5565 O O . THR D 4 146 ? -1.993 76.986 -17.815 1.00 24.26 ? 145 THR D O 1 ATOM 5566 C CB . THR D 4 146 ? -4.282 76.882 -20.183 1.00 25.78 ? 145 THR D CB 1 ATOM 5567 O OG1 . THR D 4 146 ? -4.540 77.956 -19.278 1.00 26.24 ? 145 THR D OG1 1 ATOM 5568 C CG2 . THR D 4 146 ? -5.600 76.197 -20.552 1.00 25.58 ? 145 THR D CG2 1 ATOM 5569 N N . GLY D 4 147 ? -1.242 77.178 -19.949 1.00 23.77 ? 146 GLY D N 1 ATOM 5570 C CA . GLY D 4 147 ? -0.160 78.117 -19.676 1.00 23.24 ? 146 GLY D CA 1 ATOM 5571 C C . GLY D 4 147 ? 1.059 77.532 -18.998 1.00 23.53 ? 146 GLY D C 1 ATOM 5572 O O . GLY D 4 147 ? 1.844 78.266 -18.406 1.00 24.13 ? 146 GLY D O 1 ATOM 5573 N N . PHE D 4 148 ? 1.243 76.218 -19.086 1.00 23.73 ? 147 PHE D N 1 ATOM 5574 C CA . PHE D 4 148 ? 2.328 75.579 -18.342 1.00 23.84 ? 147 PHE D CA 1 ATOM 5575 C C . PHE D 4 148 ? 3.526 75.154 -19.182 1.00 24.66 ? 147 PHE D C 1 ATOM 5576 O O . PHE D 4 148 ? 3.424 74.924 -20.383 1.00 25.21 ? 147 PHE D O 1 ATOM 5577 C CB . PHE D 4 148 ? 1.811 74.414 -17.491 1.00 22.68 ? 147 PHE D CB 1 ATOM 5578 C CG . PHE D 4 148 ? 1.159 73.323 -18.277 1.00 21.94 ? 147 PHE D CG 1 ATOM 5579 C CD1 . PHE D 4 148 ? -0.198 73.383 -18.587 1.00 22.03 ? 147 PHE D CD1 1 ATOM 5580 C CD2 . PHE D 4 148 ? 1.890 72.216 -18.693 1.00 21.03 ? 147 PHE D CD2 1 ATOM 5581 C CE1 . PHE D 4 148 ? -0.809 72.350 -19.315 1.00 21.53 ? 147 PHE D CE1 1 ATOM 5582 C CE2 . PHE D 4 148 ? 1.289 71.191 -19.420 1.00 20.74 ? 147 PHE D CE2 1 ATOM 5583 C CZ . PHE D 4 148 ? -0.054 71.251 -19.730 1.00 20.66 ? 147 PHE D CZ 1 ATOM 5584 N N . TYR D 4 149 ? 4.671 75.063 -18.522 1.00 26.57 ? 148 TYR D N 1 ATOM 5585 C CA . TYR D 4 149 ? 5.914 74.692 -19.165 1.00 27.72 ? 148 TYR D CA 1 ATOM 5586 C C . TYR D 4 149 ? 6.790 74.169 -18.064 1.00 27.59 ? 148 TYR D C 1 ATOM 5587 O O . TYR D 4 149 ? 6.802 74.753 -16.982 1.00 27.77 ? 148 TYR D O 1 ATOM 5588 C CB . TYR D 4 149 ? 6.590 75.911 -19.815 1.00 29.35 ? 148 TYR D CB 1 ATOM 5589 C CG . TYR D 4 149 ? 7.789 75.525 -20.638 1.00 31.29 ? 148 TYR D CG 1 ATOM 5590 C CD1 . TYR D 4 149 ? 7.642 75.165 -21.979 1.00 32.39 ? 148 TYR D CD1 1 ATOM 5591 C CD2 . TYR D 4 149 ? 9.070 75.480 -20.072 1.00 31.93 ? 148 TYR D CD2 1 ATOM 5592 C CE1 . TYR D 4 149 ? 8.732 74.783 -22.746 1.00 33.24 ? 148 TYR D CE1 1 ATOM 5593 C CE2 . TYR D 4 149 ? 10.173 75.097 -20.832 1.00 32.93 ? 148 TYR D CE2 1 ATOM 5594 C CZ . TYR D 4 149 ? 9.993 74.747 -22.168 1.00 33.66 ? 148 TYR D CZ 1 ATOM 5595 O OH . TYR D 4 149 ? 11.064 74.361 -22.935 1.00 33.89 ? 148 TYR D OH 1 ATOM 5596 N N . PRO D 4 150 ? 7.492 73.044 -18.303 1.00 28.63 ? 149 PRO D N 1 ATOM 5597 C CA . PRO D 4 150 ? 7.381 72.131 -19.463 1.00 30.28 ? 149 PRO D CA 1 ATOM 5598 C C . PRO D 4 150 ? 6.181 71.149 -19.392 1.00 31.46 ? 149 PRO D C 1 ATOM 5599 O O . PRO D 4 150 ? 5.316 71.277 -18.519 1.00 30.24 ? 149 PRO D O 1 ATOM 5600 C CB . PRO D 4 150 ? 8.712 71.377 -19.442 1.00 28.87 ? 149 PRO D CB 1 ATOM 5601 C CG . PRO D 4 150 ? 9.131 71.406 -18.021 1.00 28.91 ? 149 PRO D CG 1 ATOM 5602 C CD . PRO D 4 150 ? 8.601 72.664 -17.407 1.00 27.80 ? 149 PRO D CD 1 ATOM 5603 N N . ASP D 4 151 ? 6.135 70.176 -20.297 1.00 33.48 ? 150 ASP D N 1 ATOM 5604 C CA . ASP D 4 151 ? 4.941 69.346 -20.438 1.00 37.07 ? 150 ASP D CA 1 ATOM 5605 C C . ASP D 4 151 ? 4.798 68.217 -19.403 1.00 38.30 ? 150 ASP D C 1 ATOM 5606 O O . ASP D 4 151 ? 4.113 67.227 -19.666 1.00 41.67 ? 150 ASP D O 1 ATOM 5607 C CB . ASP D 4 151 ? 4.826 68.800 -21.868 1.00 39.58 ? 150 ASP D CB 1 ATOM 5608 C CG . ASP D 4 151 ? 5.847 67.712 -22.169 1.00 44.55 ? 150 ASP D CG 1 ATOM 5609 O OD1 . ASP D 4 151 ? 7.028 67.859 -21.770 1.00 47.78 ? 150 ASP D OD1 1 ATOM 5610 O OD2 . ASP D 4 151 ? 5.464 66.703 -22.812 1.00 46.74 ? 150 ASP D OD2 1 ATOM 5611 N N . HIS D 4 152 ? 5.406 68.380 -18.227 1.00 36.89 ? 151 HIS D N 1 ATOM 5612 C CA . HIS D 4 152 ? 5.393 67.343 -17.183 1.00 35.11 ? 151 HIS D CA 1 ATOM 5613 C C . HIS D 4 152 ? 4.302 67.557 -16.173 1.00 34.30 ? 151 HIS D C 1 ATOM 5614 O O . HIS D 4 152 ? 4.539 68.087 -15.072 1.00 34.13 ? 151 HIS D O 1 ATOM 5615 C CB . HIS D 4 152 ? 6.755 67.244 -16.496 1.00 34.91 ? 151 HIS D CB 1 ATOM 5616 C CG . HIS D 4 152 ? 7.766 66.449 -17.272 1.00 36.41 ? 151 HIS D CG 1 ATOM 5617 N ND1 . HIS D 4 152 ? 8.673 65.657 -16.677 1.00 38.42 ? 151 HIS D ND1 1 ATOM 5618 C CD2 . HIS D 4 152 ? 7.975 66.320 -18.646 1.00 37.70 ? 151 HIS D CD2 1 ATOM 5619 C CE1 . HIS D 4 152 ? 9.432 65.053 -17.617 1.00 38.17 ? 151 HIS D CE1 1 ATOM 5620 N NE2 . HIS D 4 152 ? 9.003 65.462 -18.822 1.00 38.07 ? 151 HIS D NE2 1 ATOM 5621 N N . VAL D 4 153 ? 3.088 67.146 -16.538 1.00 32.45 ? 152 VAL D N 1 ATOM 5622 C CA . VAL D 4 153 ? 1.953 67.241 -15.625 1.00 30.46 ? 152 VAL D CA 1 ATOM 5623 C C . VAL D 4 153 ? 1.191 65.943 -15.551 1.00 30.60 ? 152 VAL D C 1 ATOM 5624 O O . VAL D 4 153 ? 0.950 65.297 -16.567 1.00 32.11 ? 152 VAL D O 1 ATOM 5625 C CB . VAL D 4 153 ? 0.954 68.381 -16.002 1.00 29.59 ? 152 VAL D CB 1 ATOM 5626 C CG1 . VAL D 4 153 ? 1.610 69.767 -15.892 1.00 28.80 ? 152 VAL D CG1 1 ATOM 5627 C CG2 . VAL D 4 153 ? 0.319 68.157 -17.386 1.00 29.44 ? 152 VAL D CG2 1 ATOM 5628 N N . GLU D 4 154 ? 0.811 65.568 -14.339 1.00 31.12 ? 153 GLU D N 1 ATOM 5629 C CA . GLU D 4 154 ? -0.126 64.487 -14.122 1.00 31.16 ? 153 GLU D CA 1 ATOM 5630 C C . GLU D 4 154 ? -1.437 65.109 -13.739 1.00 28.72 ? 153 GLU D C 1 ATOM 5631 O O . GLU D 4 154 ? -1.537 65.763 -12.706 1.00 28.71 ? 153 GLU D O 1 ATOM 5632 C CB . GLU D 4 154 ? 0.339 63.577 -12.991 1.00 35.37 ? 153 GLU D CB 1 ATOM 5633 C CG . GLU D 4 154 ? 1.295 62.496 -13.417 1.00 42.20 ? 153 GLU D CG 1 ATOM 5634 C CD . GLU D 4 154 ? 2.355 62.198 -12.357 1.00 49.41 ? 153 GLU D CD 1 ATOM 5635 O OE1 . GLU D 4 154 ? 2.153 62.543 -11.162 1.00 49.00 ? 153 GLU D OE1 1 ATOM 5636 O OE2 . GLU D 4 154 ? 3.403 61.615 -12.732 1.00 56.22 ? 153 GLU D OE2 1 ATOM 5637 N N . LEU D 4 155 ? -2.438 64.920 -14.583 1.00 26.90 ? 154 LEU D N 1 ATOM 5638 C CA . LEU D 4 155 ? -3.795 65.349 -14.281 1.00 25.88 ? 154 LEU D CA 1 ATOM 5639 C C . LEU D 4 155 ? -4.573 64.162 -13.691 1.00 25.69 ? 154 LEU D C 1 ATOM 5640 O O . LEU D 4 155 ? -4.472 63.051 -14.213 1.00 26.62 ? 154 LEU D O 1 ATOM 5641 C CB . LEU D 4 155 ? -4.460 65.854 -15.564 1.00 25.20 ? 154 LEU D CB 1 ATOM 5642 C CG . LEU D 4 155 ? -5.798 66.581 -15.439 1.00 26.14 ? 154 LEU D CG 1 ATOM 5643 C CD1 . LEU D 4 155 ? -6.008 67.552 -16.596 1.00 25.99 ? 154 LEU D CD1 1 ATOM 5644 C CD2 . LEU D 4 155 ? -6.961 65.596 -15.316 1.00 25.38 ? 154 LEU D CD2 1 ATOM 5645 N N . SER D 4 156 ? -5.334 64.389 -12.616 1.00 24.17 ? 155 SER D N 1 ATOM 5646 C CA . SER D 4 156 ? -6.168 63.344 -12.009 1.00 22.94 ? 155 SER D CA 1 ATOM 5647 C C . SER D 4 156 ? -7.497 63.868 -11.451 1.00 23.20 ? 155 SER D C 1 ATOM 5648 O O . SER D 4 156 ? -7.604 65.029 -11.079 1.00 22.15 ? 155 SER D O 1 ATOM 5649 C CB . SER D 4 156 ? -5.401 62.594 -10.920 1.00 22.63 ? 155 SER D CB 1 ATOM 5650 O OG . SER D 4 156 ? -5.063 63.434 -9.832 1.00 22.53 ? 155 SER D OG 1 ATOM 5651 N N . TRP D 4 157 ? -8.498 62.986 -11.394 1.00 23.78 ? 156 TRP D N 1 ATOM 5652 C CA . TRP D 4 157 ? -9.851 63.337 -10.972 1.00 23.70 ? 156 TRP D CA 1 ATOM 5653 C C . TRP D 4 157 ? -10.193 62.753 -9.634 1.00 25.17 ? 156 TRP D C 1 ATOM 5654 O O . TRP D 4 157 ? -9.947 61.566 -9.385 1.00 25.66 ? 156 TRP D O 1 ATOM 5655 C CB . TRP D 4 157 ? -10.855 62.803 -11.970 1.00 23.29 ? 156 TRP D CB 1 ATOM 5656 C CG . TRP D 4 157 ? -10.956 63.586 -13.247 1.00 22.56 ? 156 TRP D CG 1 ATOM 5657 C CD1 . TRP D 4 157 ? -10.342 63.310 -14.464 1.00 21.67 ? 156 TRP D CD1 1 ATOM 5658 C CD2 . TRP D 4 157 ? -11.745 64.794 -13.478 1.00 22.41 ? 156 TRP D CD2 1 ATOM 5659 N NE1 . TRP D 4 157 ? -10.694 64.240 -15.403 1.00 21.93 ? 156 TRP D NE1 1 ATOM 5660 C CE2 . TRP D 4 157 ? -11.530 65.158 -14.880 1.00 22.64 ? 156 TRP D CE2 1 ATOM 5661 C CE3 . TRP D 4 157 ? -12.585 65.580 -12.694 1.00 22.46 ? 156 TRP D CE3 1 ATOM 5662 C CZ2 . TRP D 4 157 ? -12.132 66.272 -15.448 1.00 23.82 ? 156 TRP D CZ2 1 ATOM 5663 C CZ3 . TRP D 4 157 ? -13.190 66.698 -13.271 1.00 22.77 ? 156 TRP D CZ3 1 ATOM 5664 C CH2 . TRP D 4 157 ? -12.967 67.039 -14.616 1.00 23.99 ? 156 TRP D CH2 1 ATOM 5665 N N . TRP D 4 158 ? -10.776 63.576 -8.759 1.00 25.58 ? 157 TRP D N 1 ATOM 5666 C CA . TRP D 4 158 ? -11.167 63.132 -7.418 1.00 24.72 ? 157 TRP D CA 1 ATOM 5667 C C . TRP D 4 158 ? -12.602 63.424 -7.168 1.00 24.95 ? 157 TRP D C 1 ATOM 5668 O O . TRP D 4 158 ? -13.093 64.493 -7.527 1.00 26.13 ? 157 TRP D O 1 ATOM 5669 C CB . TRP D 4 158 ? -10.290 63.793 -6.377 1.00 24.31 ? 157 TRP D CB 1 ATOM 5670 C CG . TRP D 4 158 ? -8.843 63.427 -6.584 1.00 24.22 ? 157 TRP D CG 1 ATOM 5671 C CD1 . TRP D 4 158 ? -8.013 63.811 -7.627 1.00 24.05 ? 157 TRP D CD1 1 ATOM 5672 C CD2 . TRP D 4 158 ? -8.021 62.556 -5.745 1.00 24.15 ? 157 TRP D CD2 1 ATOM 5673 N NE1 . TRP D 4 158 ? -6.772 63.258 -7.490 1.00 24.31 ? 157 TRP D NE1 1 ATOM 5674 C CE2 . TRP D 4 158 ? -6.709 62.500 -6.378 1.00 24.31 ? 157 TRP D CE2 1 ATOM 5675 C CE3 . TRP D 4 158 ? -8.234 61.846 -4.574 1.00 24.49 ? 157 TRP D CE3 1 ATOM 5676 C CZ2 . TRP D 4 158 ? -5.672 61.762 -5.846 1.00 24.40 ? 157 TRP D CZ2 1 ATOM 5677 C CZ3 . TRP D 4 158 ? -7.181 61.107 -4.045 1.00 24.25 ? 157 TRP D CZ3 1 ATOM 5678 C CH2 . TRP D 4 158 ? -5.928 61.072 -4.665 1.00 24.44 ? 157 TRP D CH2 1 ATOM 5679 N N . VAL D 4 159 ? -13.304 62.445 -6.616 1.00 24.56 ? 158 VAL D N 1 ATOM 5680 C CA . VAL D 4 159 ? -14.688 62.623 -6.203 1.00 25.27 ? 158 VAL D CA 1 ATOM 5681 C C . VAL D 4 159 ? -14.785 62.230 -4.727 1.00 25.72 ? 158 VAL D C 1 ATOM 5682 O O . VAL D 4 159 ? -14.414 61.116 -4.350 1.00 24.55 ? 158 VAL D O 1 ATOM 5683 C CB . VAL D 4 159 ? -15.681 61.819 -7.080 1.00 25.44 ? 158 VAL D CB 1 ATOM 5684 C CG1 . VAL D 4 159 ? -17.111 61.926 -6.531 1.00 24.75 ? 158 VAL D CG1 1 ATOM 5685 C CG2 . VAL D 4 159 ? -15.633 62.312 -8.503 1.00 24.75 ? 158 VAL D CG2 1 ATOM 5686 N N . ASN D 4 160 ? -15.263 63.174 -3.910 1.00 26.47 ? 159 ASN D N 1 ATOM 5687 C CA . ASN D 4 160 ? -15.261 63.058 -2.455 1.00 27.13 ? 159 ASN D CA 1 ATOM 5688 C C . ASN D 4 160 ? -13.940 62.511 -1.932 1.00 27.51 ? 159 ASN D C 1 ATOM 5689 O O . ASN D 4 160 ? -13.923 61.509 -1.201 1.00 28.69 ? 159 ASN D O 1 ATOM 5690 C CB . ASN D 4 160 ? -16.394 62.170 -1.952 1.00 27.83 ? 159 ASN D CB 1 ATOM 5691 C CG . ASN D 4 160 ? -17.725 62.511 -2.560 1.00 29.61 ? 159 ASN D CG 1 ATOM 5692 O OD1 . ASN D 4 160 ? -18.279 63.607 -2.348 1.00 29.83 ? 159 ASN D OD1 1 ATOM 5693 N ND2 . ASN D 4 160 ? -18.274 61.554 -3.309 1.00 29.47 ? 159 ASN D ND2 1 ATOM 5694 N N . GLY D 4 161 ? -12.841 63.155 -2.325 1.00 26.12 ? 160 GLY D N 1 ATOM 5695 C CA . GLY D 4 161 ? -11.515 62.810 -1.816 1.00 25.65 ? 160 GLY D CA 1 ATOM 5696 C C . GLY D 4 161 ? -10.973 61.455 -2.227 1.00 25.93 ? 160 GLY D C 1 ATOM 5697 O O . GLY D 4 161 ? -9.947 61.023 -1.718 1.00 25.29 ? 160 GLY D O 1 ATOM 5698 N N . LYS D 4 162 ? -11.656 60.768 -3.138 1.00 27.53 ? 161 LYS D N 1 ATOM 5699 C CA . LYS D 4 162 ? -11.091 59.547 -3.719 1.00 28.91 ? 161 LYS D CA 1 ATOM 5700 C C . LYS D 4 162 ? -10.937 59.668 -5.221 1.00 27.91 ? 161 LYS D C 1 ATOM 5701 O O . LYS D 4 162 ? -11.792 60.230 -5.900 1.00 28.00 ? 161 LYS D O 1 ATOM 5702 C CB . LYS D 4 162 ? -11.890 58.303 -3.330 1.00 30.86 ? 161 LYS D CB 1 ATOM 5703 C CG . LYS D 4 162 ? -11.763 57.954 -1.842 1.00 35.05 ? 161 LYS D CG 1 ATOM 5704 C CD . LYS D 4 162 ? -12.418 56.610 -1.515 1.00 38.37 ? 161 LYS D CD 1 ATOM 5705 C CE . LYS D 4 162 ? -12.605 56.417 -0.003 1.00 39.36 ? 161 LYS D CE 1 ATOM 5706 N NZ . LYS D 4 162 ? -13.642 55.368 0.271 1.00 40.66 ? 161 LYS D NZ 1 ATOM 5707 N N . GLU D 4 163 ? -9.825 59.146 -5.724 1.00 27.41 ? 162 GLU D N 1 ATOM 5708 C CA . GLU D 4 163 ? -9.506 59.202 -7.137 1.00 26.97 ? 162 GLU D CA 1 ATOM 5709 C C . GLU D 4 163 ? -10.400 58.292 -7.982 1.00 28.17 ? 162 GLU D C 1 ATOM 5710 O O . GLU D 4 163 ? -10.668 57.139 -7.612 1.00 27.74 ? 162 GLU D O 1 ATOM 5711 C CB . GLU D 4 163 ? -8.050 58.828 -7.323 1.00 27.49 ? 162 GLU D CB 1 ATOM 5712 C CG . GLU D 4 163 ? -7.519 59.011 -8.739 1.00 28.18 ? 162 GLU D CG 1 ATOM 5713 C CD . GLU D 4 163 ? -6.012 58.954 -8.791 1.00 27.00 ? 162 GLU D CD 1 ATOM 5714 O OE1 . GLU D 4 163 ? -5.395 58.419 -7.853 1.00 26.67 ? 162 GLU D OE1 1 ATOM 5715 O OE2 . GLU D 4 163 ? -5.445 59.453 -9.767 1.00 27.22 ? 162 GLU D OE2 1 ATOM 5716 N N . VAL D 4 164 ? -10.852 58.820 -9.122 1.00 29.41 ? 163 VAL D N 1 ATOM 5717 C CA . VAL D 4 164 ? -11.695 58.075 -10.070 1.00 29.73 ? 163 VAL D CA 1 ATOM 5718 C C . VAL D 4 164 ? -10.988 57.888 -11.422 1.00 31.86 ? 163 VAL D C 1 ATOM 5719 O O . VAL D 4 164 ? -10.320 58.800 -11.920 1.00 32.12 ? 163 VAL D O 1 ATOM 5720 C CB . VAL D 4 164 ? -13.115 58.709 -10.256 1.00 28.84 ? 163 VAL D CB 1 ATOM 5721 C CG1 . VAL D 4 164 ? -13.862 58.800 -8.930 1.00 29.72 ? 163 VAL D CG1 1 ATOM 5722 C CG2 . VAL D 4 164 ? -13.039 60.065 -10.866 1.00 28.00 ? 163 VAL D CG2 1 ATOM 5723 N N . HIS D 4 165 ? -11.116 56.691 -11.994 1.00 33.60 ? 164 HIS D N 1 ATOM 5724 C CA . HIS D 4 165 ? -10.502 56.380 -13.283 1.00 32.65 ? 164 HIS D CA 1 ATOM 5725 C C . HIS D 4 165 ? -11.557 56.016 -14.264 1.00 31.61 ? 164 HIS D C 1 ATOM 5726 O O . HIS D 4 165 ? -11.396 56.219 -15.464 1.00 32.46 ? 164 HIS D O 1 ATOM 5727 C CB . HIS D 4 165 ? -9.535 55.219 -13.157 1.00 35.21 ? 164 HIS D CB 1 ATOM 5728 C CG . HIS D 4 165 ? -8.435 55.448 -12.161 1.00 37.65 ? 164 HIS D CG 1 ATOM 5729 N ND1 . HIS D 4 165 ? -7.325 56.159 -12.458 1.00 38.34 ? 164 HIS D ND1 1 ATOM 5730 C CD2 . HIS D 4 165 ? -8.298 55.028 -10.839 1.00 38.08 ? 164 HIS D CD2 1 ATOM 5731 C CE1 . HIS D 4 165 ? -6.517 56.194 -11.380 1.00 39.42 ? 164 HIS D CE1 1 ATOM 5732 N NE2 . HIS D 4 165 ? -7.114 55.499 -10.389 1.00 40.02 ? 164 HIS D NE2 1 ATOM 5733 N N . SER D 4 166 ? -12.652 55.465 -13.754 1.00 29.87 ? 165 SER D N 1 ATOM 5734 C CA . SER D 4 166 ? -13.798 55.106 -14.582 1.00 28.13 ? 165 SER D CA 1 ATOM 5735 C C . SER D 4 166 ? -14.453 56.362 -15.141 1.00 26.91 ? 165 SER D C 1 ATOM 5736 O O . SER D 4 166 ? -14.645 57.329 -14.413 1.00 27.31 ? 165 SER D O 1 ATOM 5737 C CB . SER D 4 166 ? -14.801 54.297 -13.763 1.00 27.17 ? 165 SER D CB 1 ATOM 5738 O OG . SER D 4 166 ? -15.824 53.803 -14.596 1.00 28.30 ? 165 SER D OG 1 ATOM 5739 N N . GLY D 4 167 ? -14.782 56.349 -16.429 1.00 25.27 ? 166 GLY D N 1 ATOM 5740 C CA . GLY D 4 167 ? -15.389 57.498 -17.077 1.00 25.53 ? 166 GLY D CA 1 ATOM 5741 C C . GLY D 4 167 ? -14.437 58.658 -17.308 1.00 27.12 ? 166 GLY D C 1 ATOM 5742 O O . GLY D 4 167 ? -14.868 59.777 -17.594 1.00 27.10 ? 166 GLY D O 1 ATOM 5743 N N . VAL D 4 168 ? -13.137 58.404 -17.190 1.00 27.92 ? 167 VAL D N 1 ATOM 5744 C CA . VAL D 4 168 ? -12.142 59.449 -17.386 1.00 28.76 ? 167 VAL D CA 1 ATOM 5745 C C . VAL D 4 168 ? -11.430 59.228 -18.709 1.00 30.29 ? 167 VAL D C 1 ATOM 5746 O O . VAL D 4 168 ? -11.230 58.084 -19.112 1.00 30.58 ? 167 VAL D O 1 ATOM 5747 C CB . VAL D 4 168 ? -11.097 59.467 -16.231 1.00 28.01 ? 167 VAL D CB 1 ATOM 5748 C CG1 . VAL D 4 168 ? -10.023 60.529 -16.468 1.00 26.75 ? 167 VAL D CG1 1 ATOM 5749 C CG2 . VAL D 4 168 ? -11.772 59.708 -14.896 1.00 27.30 ? 167 VAL D CG2 1 ATOM 5750 N N . CYS D 4 169 ? -11.077 60.321 -19.388 1.00 32.18 ? 168 CYS D N 1 ATOM 5751 C CA . CYS D 4 169 ? -10.085 60.276 -20.466 1.00 34.16 ? 168 CYS D CA 1 ATOM 5752 C C . CYS D 4 169 ? -9.297 61.591 -20.575 1.00 32.21 ? 168 CYS D C 1 ATOM 5753 O O . CYS D 4 169 ? -9.860 62.679 -20.506 1.00 31.12 ? 168 CYS D O 1 ATOM 5754 C CB . CYS D 4 169 ? -10.714 59.862 -21.806 1.00 38.71 ? 168 CYS D CB 1 ATOM 5755 S SG . CYS D 4 169 ? -10.916 61.163 -23.057 1.00 52.79 ? 168 CYS D SG 1 ATOM 5756 N N . THR D 4 170 ? -7.987 61.467 -20.748 1.00 30.99 ? 169 THR D N 1 ATOM 5757 C CA . THR D 4 170 ? -7.097 62.617 -20.845 1.00 30.68 ? 169 THR D CA 1 ATOM 5758 C C . THR D 4 170 ? -6.250 62.604 -22.112 1.00 31.51 ? 169 THR D C 1 ATOM 5759 O O . THR D 4 170 ? -5.668 61.574 -22.475 1.00 32.01 ? 169 THR D O 1 ATOM 5760 C CB . THR D 4 170 ? -6.174 62.688 -19.624 1.00 28.85 ? 169 THR D CB 1 ATOM 5761 O OG1 . THR D 4 170 ? -6.981 62.712 -18.442 1.00 28.57 ? 169 THR D OG1 1 ATOM 5762 C CG2 . THR D 4 170 ? -5.302 63.929 -19.670 1.00 27.01 ? 169 THR D CG2 1 ATOM 5763 N N . ASP D 4 171 ? -6.186 63.761 -22.771 1.00 32.34 ? 170 ASP D N 1 ATOM 5764 C CA . ASP D 4 171 ? -5.346 63.961 -23.947 1.00 33.56 ? 170 ASP D CA 1 ATOM 5765 C C . ASP D 4 171 ? -4.038 63.182 -23.800 1.00 34.00 ? 170 ASP D C 1 ATOM 5766 O O . ASP D 4 171 ? -3.392 63.275 -22.761 1.00 32.56 ? 170 ASP D O 1 ATOM 5767 C CB . ASP D 4 171 ? -5.064 65.458 -24.153 1.00 33.09 ? 170 ASP D CB 1 ATOM 5768 C CG . ASP D 4 171 ? -6.335 66.291 -24.223 1.00 33.05 ? 170 ASP D CG 1 ATOM 5769 O OD1 . ASP D 4 171 ? -7.420 65.696 -24.286 1.00 35.40 ? 170 ASP D OD1 1 ATOM 5770 O OD2 . ASP D 4 171 ? -6.266 67.540 -24.205 1.00 33.16 ? 170 ASP D OD2 1 ATOM 5771 N N . PRO D 4 172 ? -3.650 62.407 -24.835 1.00 36.79 ? 171 PRO D N 1 ATOM 5772 C CA . PRO D 4 172 ? -2.441 61.577 -24.699 1.00 37.70 ? 171 PRO D CA 1 ATOM 5773 C C . PRO D 4 172 ? -1.205 62.448 -24.521 1.00 38.70 ? 171 PRO D C 1 ATOM 5774 O O . PRO D 4 172 ? -0.292 62.065 -23.811 1.00 38.68 ? 171 PRO D O 1 ATOM 5775 C CB . PRO D 4 172 ? -2.380 60.783 -26.011 1.00 37.58 ? 171 PRO D CB 1 ATOM 5776 C CG . PRO D 4 172 ? -3.706 61.056 -26.726 1.00 39.62 ? 171 PRO D CG 1 ATOM 5777 C CD . PRO D 4 172 ? -4.188 62.383 -26.210 1.00 37.71 ? 171 PRO D CD 1 ATOM 5778 N N . GLN D 4 173 ? -1.191 63.621 -25.143 1.00 41.78 ? 172 GLN D N 1 ATOM 5779 C CA . GLN D 4 173 ? -0.154 64.615 -24.856 1.00 47.40 ? 172 GLN D CA 1 ATOM 5780 C C . GLN D 4 173 ? -0.751 66.034 -24.943 1.00 46.66 ? 172 GLN D C 1 ATOM 5781 O O . GLN D 4 173 ? -1.789 66.225 -25.582 1.00 46.49 ? 172 GLN D O 1 ATOM 5782 C CB . GLN D 4 173 ? 1.106 64.405 -25.749 1.00 51.33 ? 172 GLN D CB 1 ATOM 5783 C CG . GLN D 4 173 ? 1.154 65.154 -27.109 1.00 56.47 ? 172 GLN D CG 1 ATOM 5784 C CD . GLN D 4 173 ? -0.087 64.941 -27.999 1.00 58.72 ? 172 GLN D CD 1 ATOM 5785 O OE1 . GLN D 4 173 ? -0.460 63.808 -28.339 1.00 56.97 ? 172 GLN D OE1 1 ATOM 5786 N NE2 . GLN D 4 173 ? -0.717 66.047 -28.386 1.00 58.79 ? 172 GLN D NE2 1 ATOM 5787 N N . PRO D 4 174 ? -0.116 67.024 -24.285 1.00 45.11 ? 173 PRO D N 1 ATOM 5788 C CA . PRO D 4 174 ? -0.676 68.370 -24.283 1.00 44.05 ? 173 PRO D CA 1 ATOM 5789 C C . PRO D 4 174 ? -0.465 69.027 -25.631 1.00 43.84 ? 173 PRO D C 1 ATOM 5790 O O . PRO D 4 174 ? 0.404 68.590 -26.372 1.00 45.13 ? 173 PRO D O 1 ATOM 5791 C CB . PRO D 4 174 ? 0.165 69.101 -23.225 1.00 44.81 ? 173 PRO D CB 1 ATOM 5792 C CG . PRO D 4 174 ? 0.941 68.032 -22.504 1.00 45.77 ? 173 PRO D CG 1 ATOM 5793 C CD . PRO D 4 174 ? 1.141 66.964 -23.520 1.00 45.79 ? 173 PRO D CD 1 ATOM 5794 N N . LEU D 4 175 ? -1.241 70.063 -25.945 1.00 42.50 ? 174 LEU D N 1 ATOM 5795 C CA . LEU D 4 175 ? -1.007 70.838 -27.166 1.00 44.16 ? 174 LEU D CA 1 ATOM 5796 C C . LEU D 4 175 ? -0.262 72.167 -26.923 1.00 44.41 ? 174 LEU D C 1 ATOM 5797 O O . LEU D 4 175 ? -0.399 72.776 -25.866 1.00 44.04 ? 174 LEU D O 1 ATOM 5798 C CB . LEU D 4 175 ? -2.309 71.045 -27.961 1.00 44.62 ? 174 LEU D CB 1 ATOM 5799 C CG . LEU D 4 175 ? -3.518 71.766 -27.353 1.00 46.09 ? 174 LEU D CG 1 ATOM 5800 C CD1 . LEU D 4 175 ? -3.332 73.283 -27.318 1.00 45.87 ? 174 LEU D CD1 1 ATOM 5801 C CD2 . LEU D 4 175 ? -4.791 71.398 -28.119 1.00 43.98 ? 174 LEU D CD2 1 ATOM 5802 N N . LYS D 4 176 ? 0.531 72.597 -27.908 1.00 44.40 ? 175 LYS D N 1 ATOM 5803 C CA . LYS D 4 176 ? 1.252 73.872 -27.843 1.00 45.48 ? 175 LYS D CA 1 ATOM 5804 C C . LYS D 4 176 ? 0.321 75.059 -28.070 1.00 47.32 ? 175 LYS D C 1 ATOM 5805 O O . LYS D 4 176 ? -0.483 75.056 -29.002 1.00 48.89 ? 175 LYS D O 1 ATOM 5806 C CB . LYS D 4 176 ? 2.387 73.904 -28.859 1.00 44.66 ? 175 LYS D CB 1 ATOM 5807 C CG . LYS D 4 176 ? 3.520 72.957 -28.541 1.00 45.65 ? 175 LYS D CG 1 ATOM 5808 C CD . LYS D 4 176 ? 4.590 73.025 -29.601 1.00 46.49 ? 175 LYS D CD 1 ATOM 5809 C CE . LYS D 4 176 ? 5.885 72.418 -29.104 1.00 47.56 ? 175 LYS D CE 1 ATOM 5810 N NZ . LYS D 4 176 ? 6.848 72.276 -30.228 1.00 47.62 ? 175 LYS D NZ 1 ATOM 5811 N N . GLU D 4 177 ? 0.440 76.068 -27.208 1.00 48.72 ? 176 GLU D N 1 ATOM 5812 C CA . GLU D 4 177 ? -0.440 77.238 -27.233 1.00 52.04 ? 176 GLU D CA 1 ATOM 5813 C C . GLU D 4 177 ? 0.042 78.252 -28.250 1.00 58.44 ? 176 GLU D C 1 ATOM 5814 O O . GLU D 4 177 ? -0.648 79.234 -28.545 1.00 60.25 ? 176 GLU D O 1 ATOM 5815 C CB . GLU D 4 177 ? -0.472 77.912 -25.860 1.00 49.53 ? 176 GLU D CB 1 ATOM 5816 C CG . GLU D 4 177 ? -0.984 77.030 -24.739 1.00 48.38 ? 176 GLU D CG 1 ATOM 5817 C CD . GLU D 4 177 ? -1.229 77.789 -23.448 1.00 47.36 ? 176 GLU D CD 1 ATOM 5818 O OE1 . GLU D 4 177 ? -0.566 78.828 -23.209 1.00 47.94 ? 176 GLU D OE1 1 ATOM 5819 O OE2 . GLU D 4 177 ? -2.092 77.336 -22.667 1.00 43.49 ? 176 GLU D OE2 1 ATOM 5820 N N . GLN D 4 178 ? 1.238 78.001 -28.775 1.00 62.97 ? 177 GLN D N 1 ATOM 5821 C CA . GLN D 4 178 ? 1.973 78.967 -29.569 1.00 62.81 ? 177 GLN D CA 1 ATOM 5822 C C . GLN D 4 178 ? 3.029 78.230 -30.395 1.00 60.16 ? 177 GLN D C 1 ATOM 5823 O O . GLN D 4 178 ? 4.224 78.415 -30.162 1.00 57.06 ? 177 GLN D O 1 ATOM 5824 C CB . GLN D 4 178 ? 2.650 79.968 -28.623 1.00 66.10 ? 177 GLN D CB 1 ATOM 5825 C CG . GLN D 4 178 ? 2.660 81.398 -29.108 1.00 70.45 ? 177 GLN D CG 1 ATOM 5826 C CD . GLN D 4 178 ? 1.325 82.088 -28.907 1.00 72.72 ? 177 GLN D CD 1 ATOM 5827 O OE1 . GLN D 4 178 ? 0.347 81.791 -29.595 1.00 71.25 ? 177 GLN D OE1 1 ATOM 5828 N NE2 . GLN D 4 178 ? 1.282 83.025 -27.964 1.00 73.48 ? 177 GLN D NE2 1 ATOM 5829 N N . PRO D 4 179 ? 2.596 77.393 -31.364 1.00 61.21 ? 178 PRO D N 1 ATOM 5830 C CA . PRO D 4 179 ? 3.543 76.534 -32.103 1.00 63.24 ? 178 PRO D CA 1 ATOM 5831 C C . PRO D 4 179 ? 4.605 77.291 -32.922 1.00 64.06 ? 178 PRO D C 1 ATOM 5832 O O . PRO D 4 179 ? 5.660 76.731 -33.213 1.00 60.87 ? 178 PRO D O 1 ATOM 5833 C CB . PRO D 4 179 ? 2.633 75.694 -33.015 1.00 61.46 ? 178 PRO D CB 1 ATOM 5834 C CG . PRO D 4 179 ? 1.264 75.801 -32.406 1.00 61.53 ? 178 PRO D CG 1 ATOM 5835 C CD . PRO D 4 179 ? 1.211 77.185 -31.827 1.00 61.37 ? 178 PRO D CD 1 ATOM 5836 N N . ALA D 4 180 ? 4.330 78.550 -33.271 1.00 69.38 ? 179 ALA D N 1 ATOM 5837 C CA . ALA D 4 180 ? 5.300 79.412 -33.965 1.00 72.57 ? 179 ALA D CA 1 ATOM 5838 C C . ALA D 4 180 ? 6.450 79.865 -33.050 1.00 77.50 ? 179 ALA D C 1 ATOM 5839 O O . ALA D 4 180 ? 7.297 80.673 -33.451 1.00 80.48 ? 179 ALA D O 1 ATOM 5840 C CB . ALA D 4 180 ? 4.597 80.624 -34.591 1.00 68.53 ? 179 ALA D CB 1 ATOM 5841 N N . LEU D 4 181 ? 6.466 79.340 -31.824 1.00 79.35 ? 180 LEU D N 1 ATOM 5842 C CA . LEU D 4 181 ? 7.518 79.621 -30.855 1.00 81.19 ? 180 LEU D CA 1 ATOM 5843 C C . LEU D 4 181 ? 8.111 78.331 -30.292 1.00 84.76 ? 180 LEU D C 1 ATOM 5844 O O . LEU D 4 181 ? 7.416 77.325 -30.135 1.00 84.93 ? 180 LEU D O 1 ATOM 5845 C CB . LEU D 4 181 ? 6.999 80.525 -29.734 1.00 82.61 ? 180 LEU D CB 1 ATOM 5846 C CG . LEU D 4 181 ? 6.999 82.032 -30.021 1.00 83.15 ? 180 LEU D CG 1 ATOM 5847 C CD1 . LEU D 4 181 ? 5.941 82.759 -29.190 1.00 78.47 ? 180 LEU D CD1 1 ATOM 5848 C CD2 . LEU D 4 181 ? 8.392 82.633 -29.795 1.00 82.61 ? 180 LEU D CD2 1 ATOM 5849 N N . ASN D 4 182 ? 9.409 78.377 -30.004 1.00 87.75 ? 181 ASN D N 1 ATOM 5850 C CA . ASN D 4 182 ? 10.188 77.210 -29.574 1.00 85.08 ? 181 ASN D CA 1 ATOM 5851 C C . ASN D 4 182 ? 9.865 76.758 -28.152 1.00 83.18 ? 181 ASN D C 1 ATOM 5852 O O . ASN D 4 182 ? 9.876 75.557 -27.851 1.00 81.24 ? 181 ASN D O 1 ATOM 5853 C CB . ASN D 4 182 ? 11.693 77.501 -29.715 1.00 83.57 ? 181 ASN D CB 1 ATOM 5854 C CG . ASN D 4 182 ? 12.035 78.990 -29.533 1.00 82.45 ? 181 ASN D CG 1 ATOM 5855 O OD1 . ASN D 4 182 ? 11.275 79.757 -28.927 1.00 77.58 ? 181 ASN D OD1 1 ATOM 5856 N ND2 . ASN D 4 182 ? 13.180 79.398 -30.070 1.00 79.26 ? 181 ASN D ND2 1 ATOM 5857 N N . ASP D 4 183 ? 9.565 77.732 -27.294 1.00 76.40 ? 182 ASP D N 1 ATOM 5858 C CA . ASP D 4 183 ? 9.340 77.491 -25.875 1.00 69.74 ? 182 ASP D CA 1 ATOM 5859 C C . ASP D 4 183 ? 7.895 77.745 -25.463 1.00 65.06 ? 182 ASP D C 1 ATOM 5860 O O . ASP D 4 183 ? 7.612 78.133 -24.321 1.00 64.27 ? 182 ASP D O 1 ATOM 5861 C CB . ASP D 4 183 ? 10.287 78.360 -25.061 1.00 70.95 ? 182 ASP D CB 1 ATOM 5862 C CG . ASP D 4 183 ? 11.733 78.035 -25.327 1.00 75.29 ? 182 ASP D CG 1 ATOM 5863 O OD1 . ASP D 4 183 ? 12.024 76.876 -25.710 1.00 71.91 ? 182 ASP D OD1 1 ATOM 5864 O OD2 . ASP D 4 183 ? 12.577 78.941 -25.151 1.00 80.46 ? 182 ASP D OD2 1 ATOM 5865 N N . SER D 4 184 ? 6.989 77.518 -26.407 1.00 57.15 ? 183 SER D N 1 ATOM 5866 C CA . SER D 4 184 ? 5.567 77.624 -26.165 1.00 52.40 ? 183 SER D CA 1 ATOM 5867 C C . SER D 4 184 ? 5.165 76.946 -24.863 1.00 51.31 ? 183 SER D C 1 ATOM 5868 O O . SER D 4 184 ? 5.687 75.886 -24.495 1.00 52.29 ? 183 SER D O 1 ATOM 5869 C CB . SER D 4 184 ? 4.791 76.988 -27.315 1.00 51.67 ? 183 SER D CB 1 ATOM 5870 O OG . SER D 4 184 ? 3.450 76.734 -26.940 1.00 52.02 ? 183 SER D OG 1 ATOM 5871 N N . ARG D 4 185 ? 4.225 77.571 -24.174 1.00 46.93 ? 184 ARG D N 1 ATOM 5872 C CA . ARG D 4 185 ? 3.588 76.958 -23.035 1.00 42.16 ? 184 ARG D CA 1 ATOM 5873 C C . ARG D 4 185 ? 2.601 75.918 -23.566 1.00 38.56 ? 184 ARG D C 1 ATOM 5874 O O . ARG D 4 185 ? 2.198 75.981 -24.734 1.00 36.81 ? 184 ARG D O 1 ATOM 5875 C CB . ARG D 4 185 ? 2.906 78.036 -22.192 1.00 43.96 ? 184 ARG D CB 1 ATOM 5876 C CG . ARG D 4 185 ? 3.835 79.190 -21.909 1.00 46.42 ? 184 ARG D CG 1 ATOM 5877 C CD . ARG D 4 185 ? 3.179 80.357 -21.208 1.00 50.84 ? 184 ARG D CD 1 ATOM 5878 N NE . ARG D 4 185 ? 4.219 81.122 -20.519 1.00 58.31 ? 184 ARG D NE 1 ATOM 5879 C CZ . ARG D 4 185 ? 4.026 81.912 -19.465 1.00 60.40 ? 184 ARG D CZ 1 ATOM 5880 N NH1 . ARG D 4 185 ? 2.805 82.077 -18.953 1.00 62.66 ? 184 ARG D NH1 1 ATOM 5881 N NH2 . ARG D 4 185 ? 5.067 82.530 -18.918 1.00 56.68 ? 184 ARG D NH2 1 ATOM 5882 N N . TYR D 4 186 ? 2.234 74.959 -22.716 1.00 34.82 ? 185 TYR D N 1 ATOM 5883 C CA . TYR D 4 186 ? 1.339 73.870 -23.102 1.00 33.23 ? 185 TYR D CA 1 ATOM 5884 C C . TYR D 4 186 ? -0.079 74.015 -22.551 1.00 32.46 ? 185 TYR D C 1 ATOM 5885 O O . TYR D 4 186 ? -0.333 74.810 -21.652 1.00 33.14 ? 185 TYR D O 1 ATOM 5886 C CB . TYR D 4 186 ? 1.928 72.534 -22.660 1.00 32.14 ? 185 TYR D CB 1 ATOM 5887 C CG . TYR D 4 186 ? 3.222 72.163 -23.360 1.00 32.97 ? 185 TYR D CG 1 ATOM 5888 C CD1 . TYR D 4 186 ? 3.204 71.456 -24.566 1.00 31.76 ? 185 TYR D CD1 1 ATOM 5889 C CD2 . TYR D 4 186 ? 4.461 72.504 -22.810 1.00 32.40 ? 185 TYR D CD2 1 ATOM 5890 C CE1 . TYR D 4 186 ? 4.366 71.108 -25.207 1.00 31.58 ? 185 TYR D CE1 1 ATOM 5891 C CE2 . TYR D 4 186 ? 5.645 72.156 -23.451 1.00 33.52 ? 185 TYR D CE2 1 ATOM 5892 C CZ . TYR D 4 186 ? 5.587 71.455 -24.653 1.00 34.33 ? 185 TYR D CZ 1 ATOM 5893 O OH . TYR D 4 186 ? 6.752 71.098 -25.307 1.00 35.77 ? 185 TYR D OH 1 ATOM 5894 N N . SER D 4 187 ? -0.996 73.231 -23.105 1.00 31.29 ? 186 SER D N 1 ATOM 5895 C CA . SER D 4 187 ? -2.347 73.118 -22.590 1.00 31.41 ? 186 SER D CA 1 ATOM 5896 C C . SER D 4 187 ? -2.864 71.697 -22.728 1.00 31.38 ? 186 SER D C 1 ATOM 5897 O O . SER D 4 187 ? -2.538 71.004 -23.691 1.00 32.99 ? 186 SER D O 1 ATOM 5898 C CB . SER D 4 187 ? -3.285 74.078 -23.302 1.00 33.85 ? 186 SER D CB 1 ATOM 5899 O OG . SER D 4 187 ? -3.096 75.388 -22.796 1.00 37.24 ? 186 SER D OG 1 ATOM 5900 N N . LEU D 4 188 ? -3.686 71.280 -21.770 1.00 28.56 ? 187 LEU D N 1 ATOM 5901 C CA . LEU D 4 188 ? -4.125 69.914 -21.677 1.00 26.59 ? 187 LEU D CA 1 ATOM 5902 C C . LEU D 4 188 ? -5.558 69.882 -21.158 1.00 27.36 ? 187 LEU D C 1 ATOM 5903 O O . LEU D 4 188 ? -5.919 70.664 -20.264 1.00 27.05 ? 187 LEU D O 1 ATOM 5904 C CB . LEU D 4 188 ? -3.201 69.171 -20.726 1.00 25.31 ? 187 LEU D CB 1 ATOM 5905 C CG . LEU D 4 188 ? -3.527 67.721 -20.405 1.00 24.86 ? 187 LEU D CG 1 ATOM 5906 C CD1 . LEU D 4 188 ? -2.686 66.811 -21.263 1.00 25.39 ? 187 LEU D CD1 1 ATOM 5907 C CD2 . LEU D 4 188 ? -3.262 67.454 -18.951 1.00 24.42 ? 187 LEU D CD2 1 ATOM 5908 N N . SER D 4 189 ? -6.369 68.978 -21.713 1.00 26.28 ? 188 SER D N 1 ATOM 5909 C CA . SER D 4 189 ? -7.756 68.835 -21.294 1.00 25.83 ? 188 SER D CA 1 ATOM 5910 C C . SER D 4 189 ? -8.044 67.417 -20.869 1.00 25.32 ? 188 SER D C 1 ATOM 5911 O O . SER D 4 189 ? -7.361 66.494 -21.280 1.00 24.76 ? 188 SER D O 1 ATOM 5912 C CB . SER D 4 189 ? -8.700 69.193 -22.425 1.00 26.48 ? 188 SER D CB 1 ATOM 5913 O OG . SER D 4 189 ? -8.850 68.081 -23.300 1.00 29.33 ? 188 SER D OG 1 ATOM 5914 N N . SER D 4 190 ? -9.082 67.246 -20.063 1.00 25.35 ? 189 SER D N 1 ATOM 5915 C CA . SER D 4 190 ? -9.484 65.924 -19.609 1.00 25.32 ? 189 SER D CA 1 ATOM 5916 C C . SER D 4 190 ? -10.984 65.897 -19.379 1.00 25.14 ? 189 SER D C 1 ATOM 5917 O O . SER D 4 190 ? -11.589 66.931 -19.134 1.00 25.15 ? 189 SER D O 1 ATOM 5918 C CB . SER D 4 190 ? -8.749 65.561 -18.320 1.00 25.61 ? 189 SER D CB 1 ATOM 5919 O OG . SER D 4 190 ? -9.056 64.240 -17.910 1.00 26.57 ? 189 SER D OG 1 ATOM 5920 N N . ARG D 4 191 ? -11.578 64.716 -19.460 1.00 26.00 ? 190 ARG D N 1 ATOM 5921 C CA . ARG D 4 191 ? -13.008 64.568 -19.254 1.00 27.35 ? 190 ARG D CA 1 ATOM 5922 C C . ARG D 4 191 ? -13.313 63.530 -18.193 1.00 26.66 ? 190 ARG D C 1 ATOM 5923 O O . ARG D 4 191 ? -12.611 62.521 -18.070 1.00 25.69 ? 190 ARG D O 1 ATOM 5924 C CB . ARG D 4 191 ? -13.708 64.218 -20.564 1.00 30.93 ? 190 ARG D CB 1 ATOM 5925 C CG . ARG D 4 191 ? -13.843 65.408 -21.498 1.00 36.42 ? 190 ARG D CG 1 ATOM 5926 C CD . ARG D 4 191 ? -13.241 65.142 -22.887 1.00 40.72 ? 190 ARG D CD 1 ATOM 5927 N NE . ARG D 4 191 ? -11.780 65.235 -22.894 1.00 46.05 ? 190 ARG D NE 1 ATOM 5928 C CZ . ARG D 4 191 ? -11.014 65.218 -23.988 1.00 48.13 ? 190 ARG D CZ 1 ATOM 5929 N NH1 . ARG D 4 191 ? -11.550 65.114 -25.199 1.00 48.73 ? 190 ARG D NH1 1 ATOM 5930 N NH2 . ARG D 4 191 ? -9.700 65.311 -23.869 1.00 47.22 ? 190 ARG D NH2 1 ATOM 5931 N N . LEU D 4 192 ? -14.345 63.819 -17.407 1.00 26.52 ? 191 LEU D N 1 ATOM 5932 C CA . LEU D 4 192 ? -14.954 62.858 -16.505 1.00 26.84 ? 191 LEU D CA 1 ATOM 5933 C C . LEU D 4 192 ? -16.457 62.849 -16.779 1.00 27.51 ? 191 LEU D C 1 ATOM 5934 O O . LEU D 4 192 ? -17.135 63.870 -16.608 1.00 27.88 ? 191 LEU D O 1 ATOM 5935 C CB . LEU D 4 192 ? -14.681 63.226 -15.042 1.00 26.34 ? 191 LEU D CB 1 ATOM 5936 C CG . LEU D 4 192 ? -15.416 62.403 -13.972 1.00 25.83 ? 191 LEU D CG 1 ATOM 5937 C CD1 . LEU D 4 192 ? -14.982 60.951 -14.004 1.00 25.36 ? 191 LEU D CD1 1 ATOM 5938 C CD2 . LEU D 4 192 ? -15.224 62.982 -12.572 1.00 25.66 ? 191 LEU D CD2 1 ATOM 5939 N N . ARG D 4 193 ? -16.969 61.709 -17.227 1.00 28.32 ? 192 ARG D N 1 ATOM 5940 C CA . ARG D 4 193 ? -18.406 61.556 -17.464 1.00 28.96 ? 192 ARG D CA 1 ATOM 5941 C C . ARG D 4 193 ? -19.029 60.674 -16.384 1.00 28.89 ? 192 ARG D C 1 ATOM 5942 O O . ARG D 4 193 ? -18.555 59.555 -16.109 1.00 27.99 ? 192 ARG D O 1 ATOM 5943 C CB . ARG D 4 193 ? -18.692 60.999 -18.867 1.00 29.98 ? 192 ARG D CB 1 ATOM 5944 C CG . ARG D 4 193 ? -20.037 61.447 -19.450 1.00 30.78 ? 192 ARG D CG 1 ATOM 5945 C CD . ARG D 4 193 ? -20.341 60.761 -20.783 1.00 30.66 ? 192 ARG D CD 1 ATOM 5946 N NE . ARG D 4 193 ? -21.305 61.522 -21.580 1.00 30.18 ? 192 ARG D NE 1 ATOM 5947 C CZ . ARG D 4 193 ? -21.578 61.294 -22.866 1.00 30.09 ? 192 ARG D CZ 1 ATOM 5948 N NH1 . ARG D 4 193 ? -22.472 62.046 -23.507 1.00 28.85 ? 192 ARG D NH1 1 ATOM 5949 N NH2 . ARG D 4 193 ? -20.960 60.317 -23.519 1.00 30.44 ? 192 ARG D NH2 1 ATOM 5950 N N . VAL D 4 194 ? -20.071 61.207 -15.755 1.00 29.18 ? 193 VAL D N 1 ATOM 5951 C CA . VAL D 4 194 ? -20.818 60.484 -14.739 1.00 30.76 ? 193 VAL D CA 1 ATOM 5952 C C . VAL D 4 194 ? -22.282 60.514 -15.131 1.00 33.26 ? 193 VAL D C 1 ATOM 5953 O O . VAL D 4 194 ? -22.673 61.254 -16.041 1.00 34.61 ? 193 VAL D O 1 ATOM 5954 C CB . VAL D 4 194 ? -20.664 61.113 -13.341 1.00 30.06 ? 193 VAL D CB 1 ATOM 5955 C CG1 . VAL D 4 194 ? -19.189 61.204 -12.933 1.00 28.28 ? 193 VAL D CG1 1 ATOM 5956 C CG2 . VAL D 4 194 ? -21.331 62.484 -13.298 1.00 31.53 ? 193 VAL D CG2 1 ATOM 5957 N N . SER D 4 195 ? -23.088 59.706 -14.450 1.00 34.81 ? 194 SER D N 1 ATOM 5958 C CA . SER D 4 195 ? -24.524 59.695 -14.679 1.00 34.66 ? 194 SER D CA 1 ATOM 5959 C C . SER D 4 195 ? -25.098 61.020 -14.188 1.00 35.73 ? 194 SER D C 1 ATOM 5960 O O . SER D 4 195 ? -24.588 61.606 -13.227 1.00 36.11 ? 194 SER D O 1 ATOM 5961 C CB . SER D 4 195 ? -25.168 58.500 -13.976 1.00 33.88 ? 194 SER D CB 1 ATOM 5962 O OG . SER D 4 195 ? -25.503 58.796 -12.635 1.00 32.60 ? 194 SER D OG 1 ATOM 5963 N N . ALA D 4 196 ? -26.131 61.512 -14.866 1.00 37.65 ? 195 ALA D N 1 ATOM 5964 C CA . ALA D 4 196 ? -26.667 62.843 -14.567 1.00 38.61 ? 195 ALA D CA 1 ATOM 5965 C C . ALA D 4 196 ? -27.112 62.904 -13.108 1.00 39.70 ? 195 ALA D C 1 ATOM 5966 O O . ALA D 4 196 ? -26.910 63.899 -12.408 1.00 39.86 ? 195 ALA D O 1 ATOM 5967 C CB . ALA D 4 196 ? -27.807 63.180 -15.500 1.00 36.36 ? 195 ALA D CB 1 ATOM 5968 N N . THR D 4 197 ? -27.688 61.806 -12.646 1.00 40.33 ? 196 THR D N 1 ATOM 5969 C CA . THR D 4 197 ? -28.163 61.728 -11.283 1.00 42.20 ? 196 THR D CA 1 ATOM 5970 C C . THR D 4 197 ? -27.002 61.708 -10.251 1.00 43.57 ? 196 THR D C 1 ATOM 5971 O O . THR D 4 197 ? -27.202 62.030 -9.071 1.00 45.18 ? 196 THR D O 1 ATOM 5972 C CB . THR D 4 197 ? -29.169 60.561 -11.114 1.00 41.21 ? 196 THR D CB 1 ATOM 5973 O OG1 . THR D 4 197 ? -29.587 60.495 -9.753 1.00 43.93 ? 196 THR D OG1 1 ATOM 5974 C CG2 . THR D 4 197 ? -28.563 59.222 -11.530 1.00 41.09 ? 196 THR D CG2 1 ATOM 5975 N N . PHE D 4 198 ? -25.795 61.359 -10.702 1.00 40.66 ? 197 PHE D N 1 ATOM 5976 C CA . PHE D 4 198 ? -24.603 61.462 -9.857 1.00 38.23 ? 197 PHE D CA 1 ATOM 5977 C C . PHE D 4 198 ? -24.177 62.927 -9.710 1.00 38.38 ? 197 PHE D C 1 ATOM 5978 O O . PHE D 4 198 ? -23.883 63.377 -8.602 1.00 36.95 ? 197 PHE D O 1 ATOM 5979 C CB . PHE D 4 198 ? -23.447 60.619 -10.411 1.00 37.42 ? 197 PHE D CB 1 ATOM 5980 C CG . PHE D 4 198 ? -22.366 60.337 -9.404 1.00 37.25 ? 197 PHE D CG 1 ATOM 5981 C CD1 . PHE D 4 198 ? -21.213 61.120 -9.361 1.00 36.94 ? 197 PHE D CD1 1 ATOM 5982 C CD2 . PHE D 4 198 ? -22.511 59.301 -8.483 1.00 36.54 ? 197 PHE D CD2 1 ATOM 5983 C CE1 . PHE D 4 198 ? -20.213 60.871 -8.427 1.00 37.50 ? 197 PHE D CE1 1 ATOM 5984 C CE2 . PHE D 4 198 ? -21.527 59.043 -7.542 1.00 37.24 ? 197 PHE D CE2 1 ATOM 5985 C CZ . PHE D 4 198 ? -20.368 59.828 -7.511 1.00 37.81 ? 197 PHE D CZ 1 ATOM 5986 N N . TRP D 4 199 ? -24.151 63.653 -10.832 1.00 38.24 ? 198 TRP D N 1 ATOM 5987 C CA . TRP D 4 199 ? -23.875 65.096 -10.858 1.00 37.40 ? 198 TRP D CA 1 ATOM 5988 C C . TRP D 4 199 ? -24.926 65.905 -10.150 1.00 38.25 ? 198 TRP D C 1 ATOM 5989 O O . TRP D 4 199 ? -24.608 66.864 -9.453 1.00 37.49 ? 198 TRP D O 1 ATOM 5990 C CB . TRP D 4 199 ? -23.732 65.579 -12.299 1.00 36.58 ? 198 TRP D CB 1 ATOM 5991 C CG . TRP D 4 199 ? -23.709 67.084 -12.462 1.00 35.91 ? 198 TRP D CG 1 ATOM 5992 C CD1 . TRP D 4 199 ? -24.658 67.884 -13.101 1.00 36.06 ? 198 TRP D CD1 1 ATOM 5993 C CD2 . TRP D 4 199 ? -22.683 68.028 -11.979 1.00 35.73 ? 198 TRP D CD2 1 ATOM 5994 N NE1 . TRP D 4 199 ? -24.297 69.207 -13.054 1.00 35.25 ? 198 TRP D NE1 1 ATOM 5995 C CE2 . TRP D 4 199 ? -23.131 69.368 -12.393 1.00 35.25 ? 198 TRP D CE2 1 ATOM 5996 C CE3 . TRP D 4 199 ? -21.483 67.903 -11.277 1.00 35.03 ? 198 TRP D CE3 1 ATOM 5997 C CZ2 . TRP D 4 199 ? -22.396 70.513 -12.101 1.00 34.43 ? 198 TRP D CZ2 1 ATOM 5998 C CZ3 . TRP D 4 199 ? -20.751 69.067 -10.996 1.00 34.51 ? 198 TRP D CZ3 1 ATOM 5999 C CH2 . TRP D 4 199 ? -21.200 70.340 -11.402 1.00 34.04 ? 198 TRP D CH2 1 ATOM 6000 N N . GLN D 4 200 ? -26.190 65.521 -10.323 1.00 39.49 ? 199 GLN D N 1 ATOM 6001 C CA . GLN D 4 200 ? -27.312 66.219 -9.689 1.00 40.23 ? 199 GLN D CA 1 ATOM 6002 C C . GLN D 4 200 ? -27.253 66.192 -8.158 1.00 39.40 ? 199 GLN D C 1 ATOM 6003 O O . GLN D 4 200 ? -27.844 67.041 -7.493 1.00 42.25 ? 199 GLN D O 1 ATOM 6004 C CB . GLN D 4 200 ? -28.650 65.668 -10.204 1.00 39.45 ? 199 GLN D CB 1 ATOM 6005 C CG . GLN D 4 200 ? -29.082 66.293 -11.538 1.00 39.06 ? 199 GLN D CG 1 ATOM 6006 C CD . GLN D 4 200 ? -30.006 65.409 -12.379 1.00 37.57 ? 199 GLN D CD 1 ATOM 6007 O OE1 . GLN D 4 200 ? -30.384 64.300 -11.990 1.00 35.70 ? 199 GLN D OE1 1 ATOM 6008 N NE2 . GLN D 4 200 ? -30.364 65.907 -13.548 1.00 36.75 ? 199 GLN D NE2 1 ATOM 6009 N N . ASN D 4 201 ? -26.530 65.219 -7.616 1.00 36.89 ? 200 ASN D N 1 ATOM 6010 C CA . ASN D 4 201 ? -26.360 65.066 -6.175 1.00 36.20 ? 200 ASN D CA 1 ATOM 6011 C C . ASN D 4 201 ? -25.445 66.144 -5.569 1.00 36.43 ? 200 ASN D C 1 ATOM 6012 O O . ASN D 4 201 ? -24.233 66.131 -5.793 1.00 35.86 ? 200 ASN D O 1 ATOM 6013 C CB . ASN D 4 201 ? -25.814 63.667 -5.878 1.00 34.68 ? 200 ASN D CB 1 ATOM 6014 C CG . ASN D 4 201 ? -25.853 63.317 -4.409 1.00 34.33 ? 200 ASN D CG 1 ATOM 6015 O OD1 . ASN D 4 201 ? -25.855 64.192 -3.535 1.00 34.44 ? 200 ASN D OD1 1 ATOM 6016 N ND2 . ASN D 4 201 ? -25.868 62.024 -4.124 1.00 33.13 ? 200 ASN D ND2 1 ATOM 6017 N N . PRO D 4 202 ? -26.022 67.074 -4.787 1.00 37.38 ? 201 PRO D N 1 ATOM 6018 C CA . PRO D 4 202 ? -25.253 68.178 -4.201 1.00 38.15 ? 201 PRO D CA 1 ATOM 6019 C C . PRO D 4 202 ? -24.279 67.781 -3.083 1.00 38.39 ? 201 PRO D C 1 ATOM 6020 O O . PRO D 4 202 ? -23.640 68.654 -2.493 1.00 38.19 ? 201 PRO D O 1 ATOM 6021 C CB . PRO D 4 202 ? -26.342 69.102 -3.643 1.00 37.31 ? 201 PRO D CB 1 ATOM 6022 C CG . PRO D 4 202 ? -27.454 68.180 -3.322 1.00 38.02 ? 201 PRO D CG 1 ATOM 6023 C CD . PRO D 4 202 ? -27.452 67.179 -4.446 1.00 37.97 ? 201 PRO D CD 1 ATOM 6024 N N . ARG D 4 203 ? -24.161 66.493 -2.787 1.00 38.50 ? 202 ARG D N 1 ATOM 6025 C CA . ARG D 4 203 ? -23.175 66.070 -1.802 1.00 40.48 ? 202 ARG D CA 1 ATOM 6026 C C . ARG D 4 203 ? -21.917 65.460 -2.414 1.00 39.01 ? 202 ARG D C 1 ATOM 6027 O O . ARG D 4 203 ? -20.960 65.142 -1.702 1.00 38.84 ? 202 ARG D O 1 ATOM 6028 C CB . ARG D 4 203 ? -23.796 65.169 -0.742 1.00 42.75 ? 202 ARG D CB 1 ATOM 6029 C CG . ARG D 4 203 ? -24.371 65.976 0.401 1.00 47.31 ? 202 ARG D CG 1 ATOM 6030 C CD . ARG D 4 203 ? -24.700 65.107 1.576 1.00 52.96 ? 202 ARG D CD 1 ATOM 6031 N NE . ARG D 4 203 ? -25.675 64.083 1.213 1.00 57.19 ? 202 ARG D NE 1 ATOM 6032 C CZ . ARG D 4 203 ? -25.940 63.012 1.951 1.00 59.43 ? 202 ARG D CZ 1 ATOM 6033 N NH1 . ARG D 4 203 ? -25.297 62.815 3.098 1.00 58.94 ? 202 ARG D NH1 1 ATOM 6034 N NH2 . ARG D 4 203 ? -26.847 62.135 1.537 1.00 62.30 ? 202 ARG D NH2 1 ATOM 6035 N N . ASN D 4 204 ? -21.922 65.320 -3.735 1.00 36.43 ? 203 ASN D N 1 ATOM 6036 C CA . ASN D 4 204 ? -20.743 64.888 -4.459 1.00 36.09 ? 203 ASN D CA 1 ATOM 6037 C C . ASN D 4 204 ? -19.838 66.055 -4.814 1.00 35.27 ? 203 ASN D C 1 ATOM 6038 O O . ASN D 4 204 ? -20.262 67.044 -5.419 1.00 37.23 ? 203 ASN D O 1 ATOM 6039 C CB . ASN D 4 204 ? -21.140 64.095 -5.695 1.00 36.45 ? 203 ASN D CB 1 ATOM 6040 C CG . ASN D 4 204 ? -21.616 62.711 -5.347 1.00 37.22 ? 203 ASN D CG 1 ATOM 6041 O OD1 . ASN D 4 204 ? -21.348 62.216 -4.255 1.00 35.91 ? 203 ASN D OD1 1 ATOM 6042 N ND2 . ASN D 4 204 ? -22.330 62.076 -6.265 1.00 38.43 ? 203 ASN D ND2 1 ATOM 6043 N N . HIS D 4 205 ? -18.586 65.940 -4.408 1.00 33.68 ? 204 HIS D N 1 ATOM 6044 C CA . HIS D 4 205 ? -17.636 67.010 -4.595 1.00 33.34 ? 204 HIS D CA 1 ATOM 6045 C C . HIS D 4 205 ? -16.661 66.599 -5.652 1.00 32.25 ? 204 HIS D C 1 ATOM 6046 O O . HIS D 4 205 ? -16.014 65.558 -5.549 1.00 32.56 ? 204 HIS D O 1 ATOM 6047 C CB . HIS D 4 205 ? -16.946 67.331 -3.276 1.00 33.76 ? 204 HIS D CB 1 ATOM 6048 C CG . HIS D 4 205 ? -16.051 68.548 -3.327 1.00 35.66 ? 204 HIS D CG 1 ATOM 6049 N ND1 . HIS D 4 205 ? -14.890 68.617 -2.650 1.00 36.64 ? 204 HIS D ND1 1 ATOM 6050 C CD2 . HIS D 4 205 ? -16.191 69.766 -3.997 1.00 36.78 ? 204 HIS D CD2 1 ATOM 6051 C CE1 . HIS D 4 205 ? -14.314 69.816 -2.873 1.00 38.15 ? 204 HIS D CE1 1 ATOM 6052 N NE2 . HIS D 4 205 ? -15.112 70.517 -3.700 1.00 37.31 ? 204 HIS D NE2 1 ATOM 6053 N N . PHE D 4 206 ? -16.574 67.411 -6.693 1.00 30.68 ? 205 PHE D N 1 ATOM 6054 C CA . PHE D 4 206 ? -15.763 67.097 -7.850 1.00 29.38 ? 205 PHE D CA 1 ATOM 6055 C C . PHE D 4 206 ? -14.544 67.979 -7.878 1.00 28.06 ? 205 PHE D C 1 ATOM 6056 O O . PHE D 4 206 ? -14.642 69.202 -7.700 1.00 26.78 ? 205 PHE D O 1 ATOM 6057 C CB . PHE D 4 206 ? -16.581 67.282 -9.117 1.00 30.52 ? 205 PHE D CB 1 ATOM 6058 C CG . PHE D 4 206 ? -17.732 66.339 -9.219 1.00 31.32 ? 205 PHE D CG 1 ATOM 6059 C CD1 . PHE D 4 206 ? -18.973 66.675 -8.685 1.00 32.75 ? 205 PHE D CD1 1 ATOM 6060 C CD2 . PHE D 4 206 ? -17.577 65.105 -9.834 1.00 31.80 ? 205 PHE D CD2 1 ATOM 6061 C CE1 . PHE D 4 206 ? -20.047 65.787 -8.762 1.00 33.59 ? 205 PHE D CE1 1 ATOM 6062 C CE2 . PHE D 4 206 ? -18.647 64.204 -9.919 1.00 32.94 ? 205 PHE D CE2 1 ATOM 6063 C CZ . PHE D 4 206 ? -19.879 64.541 -9.386 1.00 32.60 ? 205 PHE D CZ 1 ATOM 6064 N N . ARG D 4 207 ? -13.388 67.351 -8.078 1.00 27.17 ? 206 ARG D N 1 ATOM 6065 C CA . ARG D 4 207 ? -12.137 68.093 -8.139 1.00 27.28 ? 206 ARG D CA 1 ATOM 6066 C C . ARG D 4 207 ? -11.209 67.597 -9.255 1.00 27.85 ? 206 ARG D C 1 ATOM 6067 O O . ARG D 4 207 ? -10.847 66.414 -9.301 1.00 29.42 ? 206 ARG D O 1 ATOM 6068 C CB . ARG D 4 207 ? -11.432 68.101 -6.777 1.00 25.46 ? 206 ARG D CB 1 ATOM 6069 C CG . ARG D 4 207 ? -10.208 69.000 -6.761 1.00 26.65 ? 206 ARG D CG 1 ATOM 6070 C CD . ARG D 4 207 ? -9.504 69.017 -5.430 1.00 26.53 ? 206 ARG D CD 1 ATOM 6071 N NE . ARG D 4 207 ? -10.292 69.670 -4.390 1.00 26.95 ? 206 ARG D NE 1 ATOM 6072 C CZ . ARG D 4 207 ? -10.251 70.971 -4.127 1.00 28.46 ? 206 ARG D CZ 1 ATOM 6073 N NH1 . ARG D 4 207 ? -11.001 71.472 -3.157 1.00 29.44 ? 206 ARG D NH1 1 ATOM 6074 N NH2 . ARG D 4 207 ? -9.473 71.784 -4.837 1.00 28.99 ? 206 ARG D NH2 1 ATOM 6075 N N . CYS D 4 208 ? -10.843 68.508 -10.150 1.00 27.56 ? 207 CYS D N 1 ATOM 6076 C CA . CYS D 4 208 ? -9.797 68.246 -11.121 1.00 28.00 ? 207 CYS D CA 1 ATOM 6077 C C . CYS D 4 208 ? -8.486 68.695 -10.535 1.00 25.79 ? 207 CYS D C 1 ATOM 6078 O O . CYS D 4 208 ? -8.373 69.836 -10.115 1.00 27.12 ? 207 CYS D O 1 ATOM 6079 C CB . CYS D 4 208 ? -10.019 69.028 -12.416 1.00 31.61 ? 207 CYS D CB 1 ATOM 6080 S SG . CYS D 4 208 ? -8.593 68.748 -13.535 1.00 42.15 ? 207 CYS D SG 1 ATOM 6081 N N . GLN D 4 209 ? -7.485 67.828 -10.546 1.00 24.29 ? 208 GLN D N 1 ATOM 6082 C CA . GLN D 4 209 ? -6.182 68.137 -9.941 1.00 23.71 ? 208 GLN D CA 1 ATOM 6083 C C . GLN D 4 209 ? -5.027 67.923 -10.909 1.00 23.51 ? 208 GLN D C 1 ATOM 6084 O O . GLN D 4 209 ? -4.914 66.859 -11.530 1.00 23.13 ? 208 GLN D O 1 ATOM 6085 C CB . GLN D 4 209 ? -5.957 67.277 -8.702 1.00 23.01 ? 208 GLN D CB 1 ATOM 6086 C CG . GLN D 4 209 ? -4.521 67.245 -8.241 1.00 24.02 ? 208 GLN D CG 1 ATOM 6087 C CD . GLN D 4 209 ? -4.257 66.205 -7.170 1.00 24.21 ? 208 GLN D CD 1 ATOM 6088 O OE1 . GLN D 4 209 ? -4.731 66.332 -6.043 1.00 25.29 ? 208 GLN D OE1 1 ATOM 6089 N NE2 . GLN D 4 209 ? -3.480 65.188 -7.507 1.00 23.14 ? 208 GLN D NE2 1 ATOM 6090 N N . VAL D 4 210 ? -4.161 68.928 -11.025 1.00 23.24 ? 209 VAL D N 1 ATOM 6091 C CA . VAL D 4 210 ? -2.944 68.803 -11.834 1.00 22.92 ? 209 VAL D CA 1 ATOM 6092 C C . VAL D 4 210 ? -1.715 68.901 -10.959 1.00 22.91 ? 209 VAL D C 1 ATOM 6093 O O . VAL D 4 210 ? -1.526 69.897 -10.256 1.00 23.56 ? 209 VAL D O 1 ATOM 6094 C CB . VAL D 4 210 ? -2.866 69.875 -12.954 1.00 22.79 ? 209 VAL D CB 1 ATOM 6095 C CG1 . VAL D 4 210 ? -1.478 69.891 -13.606 1.00 22.16 ? 209 VAL D CG1 1 ATOM 6096 C CG2 . VAL D 4 210 ? -3.935 69.623 -13.997 1.00 22.61 ? 209 VAL D CG2 1 ATOM 6097 N N . GLN D 4 211 ? -0.895 67.854 -10.990 1.00 23.42 ? 210 GLN D N 1 ATOM 6098 C CA . GLN D 4 211 ? 0.415 67.864 -10.342 1.00 23.07 ? 210 GLN D CA 1 ATOM 6099 C C . GLN D 4 211 ? 1.414 68.367 -11.374 1.00 23.07 ? 210 GLN D C 1 ATOM 6100 O O . GLN D 4 211 ? 1.621 67.735 -12.407 1.00 23.54 ? 210 GLN D O 1 ATOM 6101 C CB . GLN D 4 211 ? 0.779 66.463 -9.856 1.00 23.43 ? 210 GLN D CB 1 ATOM 6102 C CG . GLN D 4 211 ? 2.213 66.304 -9.357 1.00 24.51 ? 210 GLN D CG 1 ATOM 6103 C CD . GLN D 4 211 ? 2.460 67.002 -8.028 1.00 25.41 ? 210 GLN D CD 1 ATOM 6104 O OE1 . GLN D 4 211 ? 3.106 68.058 -7.979 1.00 26.25 ? 210 GLN D OE1 1 ATOM 6105 N NE2 . GLN D 4 211 ? 1.927 66.434 -6.948 1.00 24.19 ? 210 GLN D NE2 1 ATOM 6106 N N . PHE D 4 212 ? 1.996 69.530 -11.120 1.00 22.65 ? 211 PHE D N 1 ATOM 6107 C CA . PHE D 4 212 ? 2.968 70.110 -12.038 1.00 22.47 ? 211 PHE D CA 1 ATOM 6108 C C . PHE D 4 212 ? 4.373 69.863 -11.492 1.00 23.21 ? 211 PHE D C 1 ATOM 6109 O O . PHE D 4 212 ? 4.601 69.986 -10.291 1.00 24.17 ? 211 PHE D O 1 ATOM 6110 C CB . PHE D 4 212 ? 2.681 71.609 -12.219 1.00 21.57 ? 211 PHE D CB 1 ATOM 6111 C CG . PHE D 4 212 ? 3.809 72.386 -12.847 1.00 20.66 ? 211 PHE D CG 1 ATOM 6112 C CD1 . PHE D 4 212 ? 3.977 72.402 -14.227 1.00 20.39 ? 211 PHE D CD1 1 ATOM 6113 C CD2 . PHE D 4 212 ? 4.696 73.107 -12.053 1.00 19.86 ? 211 PHE D CD2 1 ATOM 6114 C CE1 . PHE D 4 212 ? 5.030 73.103 -14.805 1.00 20.41 ? 211 PHE D CE1 1 ATOM 6115 C CE2 . PHE D 4 212 ? 5.728 73.823 -12.615 1.00 20.02 ? 211 PHE D CE2 1 ATOM 6116 C CZ . PHE D 4 212 ? 5.905 73.823 -14.000 1.00 20.26 ? 211 PHE D CZ 1 ATOM 6117 N N . TYR D 4 213 ? 5.307 69.496 -12.365 1.00 23.73 ? 212 TYR D N 1 ATOM 6118 C CA . TYR D 4 213 ? 6.696 69.306 -11.951 1.00 23.91 ? 212 TYR D CA 1 ATOM 6119 C C . TYR D 4 213 ? 7.568 70.447 -12.471 1.00 24.90 ? 212 TYR D C 1 ATOM 6120 O O . TYR D 4 213 ? 7.660 70.661 -13.682 1.00 24.82 ? 212 TYR D O 1 ATOM 6121 C CB . TYR D 4 213 ? 7.212 67.946 -12.420 1.00 23.10 ? 212 TYR D CB 1 ATOM 6122 C CG . TYR D 4 213 ? 6.538 66.809 -11.706 1.00 23.46 ? 212 TYR D CG 1 ATOM 6123 C CD1 . TYR D 4 213 ? 5.390 66.208 -12.240 1.00 23.31 ? 212 TYR D CD1 1 ATOM 6124 C CD2 . TYR D 4 213 ? 7.020 66.347 -10.474 1.00 23.35 ? 212 TYR D CD2 1 ATOM 6125 C CE1 . TYR D 4 213 ? 4.751 65.169 -11.578 1.00 23.23 ? 212 TYR D CE1 1 ATOM 6126 C CE2 . TYR D 4 213 ? 6.388 65.300 -9.796 1.00 23.00 ? 212 TYR D CE2 1 ATOM 6127 C CZ . TYR D 4 213 ? 5.251 64.721 -10.356 1.00 23.44 ? 212 TYR D CZ 1 ATOM 6128 O OH . TYR D 4 213 ? 4.612 63.689 -9.708 1.00 23.47 ? 212 TYR D OH 1 ATOM 6129 N N . GLY D 4 214 ? 8.192 71.184 -11.553 1.00 24.89 ? 213 GLY D N 1 ATOM 6130 C CA . GLY D 4 214 ? 9.021 72.313 -11.925 1.00 26.08 ? 213 GLY D CA 1 ATOM 6131 C C . GLY D 4 214 ? 10.240 72.421 -11.047 1.00 28.87 ? 213 GLY D C 1 ATOM 6132 O O . GLY D 4 214 ? 10.984 71.455 -10.876 1.00 30.13 ? 213 GLY D O 1 ATOM 6133 N N . LEU D 4 215 ? 10.450 73.601 -10.484 1.00 31.16 ? 214 LEU D N 1 ATOM 6134 C CA . LEU D 4 215 ? 11.651 73.852 -9.705 1.00 33.48 ? 214 LEU D CA 1 ATOM 6135 C C . LEU D 4 215 ? 11.569 73.285 -8.299 1.00 36.60 ? 214 LEU D C 1 ATOM 6136 O O . LEU D 4 215 ? 10.478 72.955 -7.789 1.00 36.66 ? 214 LEU D O 1 ATOM 6137 C CB . LEU D 4 215 ? 11.976 75.343 -9.664 1.00 33.45 ? 214 LEU D CB 1 ATOM 6138 C CG . LEU D 4 215 ? 12.832 75.871 -10.820 1.00 33.50 ? 214 LEU D CG 1 ATOM 6139 C CD1 . LEU D 4 215 ? 12.066 75.837 -12.123 1.00 33.25 ? 214 LEU D CD1 1 ATOM 6140 C CD2 . LEU D 4 215 ? 13.319 77.289 -10.545 1.00 33.81 ? 214 LEU D CD2 1 ATOM 6141 N N . SER D 4 216 ? 12.749 73.154 -7.700 1.00 38.83 ? 215 SER D N 1 ATOM 6142 C CA . SER D 4 216 ? 12.906 72.742 -6.318 1.00 42.30 ? 215 SER D CA 1 ATOM 6143 C C . SER D 4 216 ? 13.178 73.984 -5.464 1.00 43.46 ? 215 SER D C 1 ATOM 6144 O O . SER D 4 216 ? 13.587 75.017 -5.990 1.00 44.10 ? 215 SER D O 1 ATOM 6145 C CB . SER D 4 216 ? 14.069 71.760 -6.220 1.00 43.38 ? 215 SER D CB 1 ATOM 6146 O OG . SER D 4 216 ? 14.409 71.515 -4.869 1.00 48.63 ? 215 SER D OG 1 ATOM 6147 N N . GLU D 4 217 ? 12.950 73.891 -4.156 1.00 46.64 ? 216 GLU D N 1 ATOM 6148 C CA . GLU D 4 217 ? 13.334 74.977 -3.239 1.00 54.29 ? 216 GLU D CA 1 ATOM 6149 C C . GLU D 4 217 ? 14.822 75.374 -3.399 1.00 57.55 ? 216 GLU D C 1 ATOM 6150 O O . GLU D 4 217 ? 15.204 76.505 -3.102 1.00 56.57 ? 216 GLU D O 1 ATOM 6151 C CB . GLU D 4 217 ? 13.035 74.602 -1.778 1.00 54.08 ? 216 GLU D CB 1 ATOM 6152 N N . ASN D 4 218 ? 15.635 74.440 -3.899 1.00 60.48 ? 217 ASN D N 1 ATOM 6153 C CA . ASN D 4 218 ? 17.083 74.612 -4.037 1.00 60.78 ? 217 ASN D CA 1 ATOM 6154 C C . ASN D 4 218 ? 17.543 75.261 -5.343 1.00 60.03 ? 217 ASN D C 1 ATOM 6155 O O . ASN D 4 218 ? 18.663 75.758 -5.423 1.00 62.20 ? 217 ASN D O 1 ATOM 6156 C CB . ASN D 4 218 ? 17.791 73.260 -3.887 1.00 65.97 ? 217 ASN D CB 1 ATOM 6157 C CG . ASN D 4 218 ? 17.239 72.425 -2.735 1.00 70.14 ? 217 ASN D CG 1 ATOM 6158 O OD1 . ASN D 4 218 ? 16.869 71.264 -2.927 1.00 72.11 ? 217 ASN D OD1 1 ATOM 6159 N ND2 . ASN D 4 218 ? 17.185 73.011 -1.535 1.00 66.57 ? 217 ASN D ND2 1 ATOM 6160 N N . ASP D 4 219 ? 16.703 75.234 -6.374 1.00 57.56 ? 218 ASP D N 1 ATOM 6161 C CA . ASP D 4 219 ? 17.038 75.898 -7.634 1.00 56.11 ? 218 ASP D CA 1 ATOM 6162 C C . ASP D 4 219 ? 16.952 77.416 -7.441 1.00 54.68 ? 218 ASP D C 1 ATOM 6163 O O . ASP D 4 219 ? 16.084 77.897 -6.714 1.00 53.35 ? 218 ASP D O 1 ATOM 6164 C CB . ASP D 4 219 ? 16.105 75.440 -8.768 1.00 57.70 ? 218 ASP D CB 1 ATOM 6165 C CG . ASP D 4 219 ? 16.143 73.923 -9.006 1.00 58.66 ? 218 ASP D CG 1 ATOM 6166 O OD1 . ASP D 4 219 ? 17.218 73.308 -8.867 1.00 61.00 ? 218 ASP D OD1 1 ATOM 6167 O OD2 . ASP D 4 219 ? 15.092 73.343 -9.353 1.00 57.51 ? 218 ASP D OD2 1 ATOM 6168 N N . GLU D 4 220 ? 17.860 78.159 -8.072 1.00 53.54 ? 219 GLU D N 1 ATOM 6169 C CA . GLU D 4 220 ? 17.890 79.625 -7.969 1.00 53.45 ? 219 GLU D CA 1 ATOM 6170 C C . GLU D 4 220 ? 16.866 80.264 -8.884 1.00 48.84 ? 219 GLU D C 1 ATOM 6171 O O . GLU D 4 220 ? 16.534 79.715 -9.922 1.00 49.91 ? 219 GLU D O 1 ATOM 6172 C CB . GLU D 4 220 ? 19.279 80.167 -8.305 1.00 59.49 ? 219 GLU D CB 1 ATOM 6173 C CG . GLU D 4 220 ? 20.253 80.126 -7.135 1.00 68.76 ? 219 GLU D CG 1 ATOM 6174 C CD . GLU D 4 220 ? 21.710 80.191 -7.571 1.00 74.61 ? 219 GLU D CD 1 ATOM 6175 O OE1 . GLU D 4 220 ? 21.984 80.075 -8.790 1.00 75.90 ? 219 GLU D OE1 1 ATOM 6176 O OE2 . GLU D 4 220 ? 22.586 80.352 -6.687 1.00 76.86 ? 219 GLU D OE2 1 ATOM 6177 N N . TRP D 4 221 ? 16.364 81.429 -8.501 1.00 45.99 ? 220 TRP D N 1 ATOM 6178 C CA . TRP D 4 221 ? 15.338 82.095 -9.289 1.00 43.60 ? 220 TRP D CA 1 ATOM 6179 C C . TRP D 4 221 ? 15.631 83.549 -9.422 1.00 44.80 ? 220 TRP D C 1 ATOM 6180 O O . TRP D 4 221 ? 15.734 84.266 -8.428 1.00 45.52 ? 220 TRP D O 1 ATOM 6181 C CB . TRP D 4 221 ? 13.950 81.874 -8.696 1.00 39.23 ? 220 TRP D CB 1 ATOM 6182 C CG . TRP D 4 221 ? 12.855 82.269 -9.649 1.00 34.92 ? 220 TRP D CG 1 ATOM 6183 C CD1 . TRP D 4 221 ? 11.860 83.218 -9.460 1.00 34.55 ? 220 TRP D CD1 1 ATOM 6184 C CD2 . TRP D 4 221 ? 12.633 81.748 -10.998 1.00 33.88 ? 220 TRP D CD2 1 ATOM 6185 N NE1 . TRP D 4 221 ? 11.058 83.310 -10.563 1.00 33.80 ? 220 TRP D NE1 1 ATOM 6186 C CE2 . TRP D 4 221 ? 11.469 82.456 -11.522 1.00 33.65 ? 220 TRP D CE2 1 ATOM 6187 C CE3 . TRP D 4 221 ? 13.259 80.793 -11.794 1.00 33.07 ? 220 TRP D CE3 1 ATOM 6188 C CZ2 . TRP D 4 221 ? 10.971 82.204 -12.788 1.00 33.79 ? 220 TRP D CZ2 1 ATOM 6189 C CZ3 . TRP D 4 221 ? 12.753 80.551 -13.066 1.00 31.44 ? 220 TRP D CZ3 1 ATOM 6190 C CH2 . TRP D 4 221 ? 11.636 81.239 -13.550 1.00 32.76 ? 220 TRP D CH2 1 ATOM 6191 N N . THR D 4 222 ? 15.749 83.995 -10.665 1.00 45.95 ? 221 THR D N 1 ATOM 6192 C CA . THR D 4 222 ? 16.329 85.299 -10.964 1.00 47.51 ? 221 THR D CA 1 ATOM 6193 C C . THR D 4 222 ? 15.309 86.320 -11.453 1.00 47.54 ? 221 THR D C 1 ATOM 6194 O O . THR D 4 222 ? 15.660 87.475 -11.691 1.00 49.32 ? 221 THR D O 1 ATOM 6195 C CB . THR D 4 222 ? 17.436 85.152 -12.024 1.00 49.90 ? 221 THR D CB 1 ATOM 6196 O OG1 . THR D 4 222 ? 17.001 84.221 -13.031 1.00 55.05 ? 221 THR D OG1 1 ATOM 6197 C CG2 . THR D 4 222 ? 18.724 84.643 -11.385 1.00 46.70 ? 221 THR D CG2 1 ATOM 6198 N N . GLN D 4 223 ? 14.057 85.887 -11.603 1.00 46.40 ? 222 GLN D N 1 ATOM 6199 C CA . GLN D 4 223 ? 12.976 86.717 -12.147 1.00 45.03 ? 222 GLN D CA 1 ATOM 6200 C C . GLN D 4 223 ? 12.051 87.240 -11.047 1.00 49.23 ? 222 GLN D C 1 ATOM 6201 O O . GLN D 4 223 ? 12.320 87.063 -9.851 1.00 52.49 ? 222 GLN D O 1 ATOM 6202 C CB . GLN D 4 223 ? 12.154 85.926 -13.167 1.00 41.89 ? 222 GLN D CB 1 ATOM 6203 C CG . GLN D 4 223 ? 12.948 85.276 -14.292 1.00 39.42 ? 222 GLN D CG 1 ATOM 6204 C CD . GLN D 4 223 ? 12.071 84.465 -15.233 1.00 38.87 ? 222 GLN D CD 1 ATOM 6205 O OE1 . GLN D 4 223 ? 10.902 84.786 -15.447 1.00 39.68 ? 222 GLN D OE1 1 ATOM 6206 N NE2 . GLN D 4 223 ? 12.633 83.405 -15.800 1.00 38.69 ? 222 GLN D NE2 1 ATOM 6207 N N . ASP D 4 224 ? 10.951 87.865 -11.454 1.00 51.09 ? 223 ASP D N 1 ATOM 6208 C CA . ASP D 4 224 ? 10.055 88.519 -10.504 1.00 52.22 ? 223 ASP D CA 1 ATOM 6209 C C . ASP D 4 224 ? 8.762 87.768 -10.246 1.00 51.73 ? 223 ASP D C 1 ATOM 6210 O O . ASP D 4 224 ? 8.254 87.786 -9.123 1.00 54.99 ? 223 ASP D O 1 ATOM 6211 C CB . ASP D 4 224 ? 9.771 89.958 -10.931 1.00 56.56 ? 223 ASP D CB 1 ATOM 6212 C CG . ASP D 4 224 ? 10.951 90.887 -10.667 1.00 61.47 ? 223 ASP D CG 1 ATOM 6213 O OD1 . ASP D 4 224 ? 10.707 92.071 -10.355 1.00 67.94 ? 223 ASP D OD1 1 ATOM 6214 O OD2 . ASP D 4 224 ? 12.121 90.441 -10.757 1.00 59.52 ? 223 ASP D OD2 1 ATOM 6215 N N . ARG D 4 225 ? 8.233 87.099 -11.268 1.00 48.11 ? 224 ARG D N 1 ATOM 6216 C CA . ARG D 4 225 ? 7.096 86.197 -11.071 1.00 41.13 ? 224 ARG D CA 1 ATOM 6217 C C . ARG D 4 225 ? 7.469 85.137 -10.044 1.00 40.61 ? 224 ARG D C 1 ATOM 6218 O O . ARG D 4 225 ? 8.642 84.754 -9.939 1.00 42.61 ? 224 ARG D O 1 ATOM 6219 C CB . ARG D 4 225 ? 6.668 85.547 -12.388 1.00 39.05 ? 224 ARG D CB 1 ATOM 6220 C CG . ARG D 4 225 ? 7.774 84.888 -13.196 1.00 36.67 ? 224 ARG D CG 1 ATOM 6221 C CD . ARG D 4 225 ? 7.181 84.240 -14.433 1.00 35.93 ? 224 ARG D CD 1 ATOM 6222 N NE . ARG D 4 225 ? 8.142 83.428 -15.178 1.00 35.38 ? 224 ARG D NE 1 ATOM 6223 C CZ . ARG D 4 225 ? 8.185 82.097 -15.159 1.00 35.10 ? 224 ARG D CZ 1 ATOM 6224 N NH1 . ARG D 4 225 ? 7.320 81.399 -14.432 1.00 35.04 ? 224 ARG D NH1 1 ATOM 6225 N NH2 . ARG D 4 225 ? 9.102 81.458 -15.873 1.00 34.81 ? 224 ARG D NH2 1 ATOM 6226 N N . ALA D 4 226 ? 6.479 84.676 -9.281 1.00 38.05 ? 225 ALA D N 1 ATOM 6227 C CA . ALA D 4 226 ? 6.695 83.657 -8.267 1.00 35.10 ? 225 ALA D CA 1 ATOM 6228 C C . ALA D 4 226 ? 7.459 82.476 -8.850 1.00 35.87 ? 225 ALA D C 1 ATOM 6229 O O . ALA D 4 226 ? 7.298 82.133 -10.031 1.00 37.52 ? 225 ALA D O 1 ATOM 6230 C CB . ALA D 4 226 ? 5.384 83.205 -7.692 1.00 34.46 ? 225 ALA D CB 1 ATOM 6231 N N . LYS D 4 227 ? 8.297 81.873 -8.012 1.00 34.14 ? 226 LYS D N 1 ATOM 6232 C CA . LYS D 4 227 ? 9.117 80.721 -8.374 1.00 32.53 ? 226 LYS D CA 1 ATOM 6233 C C . LYS D 4 227 ? 8.266 79.500 -8.749 1.00 31.82 ? 226 LYS D C 1 ATOM 6234 O O . LYS D 4 227 ? 7.529 78.981 -7.909 1.00 33.11 ? 226 LYS D O 1 ATOM 6235 C CB . LYS D 4 227 ? 10.014 80.387 -7.195 1.00 32.10 ? 226 LYS D CB 1 ATOM 6236 C CG . LYS D 4 227 ? 11.093 79.386 -7.452 1.00 32.32 ? 226 LYS D CG 1 ATOM 6237 C CD . LYS D 4 227 ? 11.946 79.332 -6.207 1.00 34.83 ? 226 LYS D CD 1 ATOM 6238 C CE . LYS D 4 227 ? 13.188 78.506 -6.403 1.00 37.42 ? 226 LYS D CE 1 ATOM 6239 N NZ . LYS D 4 227 ? 14.002 78.538 -5.153 1.00 40.83 ? 226 LYS D NZ 1 ATOM 6240 N N . PRO D 4 228 ? 8.383 79.024 -10.005 1.00 30.69 ? 227 PRO D N 1 ATOM 6241 C CA . PRO D 4 228 ? 7.518 77.972 -10.536 1.00 29.29 ? 227 PRO D CA 1 ATOM 6242 C C . PRO D 4 228 ? 7.888 76.600 -9.990 1.00 28.46 ? 227 PRO D C 1 ATOM 6243 O O . PRO D 4 228 ? 8.289 75.705 -10.747 1.00 27.79 ? 227 PRO D O 1 ATOM 6244 C CB . PRO D 4 228 ? 7.768 78.043 -12.042 1.00 29.68 ? 227 PRO D CB 1 ATOM 6245 C CG . PRO D 4 228 ? 9.163 78.515 -12.164 1.00 30.56 ? 227 PRO D CG 1 ATOM 6246 C CD . PRO D 4 228 ? 9.424 79.415 -10.974 1.00 31.06 ? 227 PRO D CD 1 ATOM 6247 N N . VAL D 4 229 ? 7.731 76.454 -8.676 1.00 26.98 ? 228 VAL D N 1 ATOM 6248 C CA . VAL D 4 229 ? 8.065 75.224 -7.971 1.00 26.84 ? 228 VAL D CA 1 ATOM 6249 C C . VAL D 4 229 ? 7.115 74.088 -8.328 1.00 25.92 ? 228 VAL D C 1 ATOM 6250 O O . VAL D 4 229 ? 5.983 74.327 -8.748 1.00 25.34 ? 228 VAL D O 1 ATOM 6251 C CB . VAL D 4 229 ? 8.069 75.416 -6.416 1.00 26.75 ? 228 VAL D CB 1 ATOM 6252 C CG1 . VAL D 4 229 ? 9.230 76.293 -5.982 1.00 26.21 ? 228 VAL D CG1 1 ATOM 6253 C CG2 . VAL D 4 229 ? 6.724 75.977 -5.918 1.00 26.48 ? 228 VAL D CG2 1 ATOM 6254 N N . THR D 4 230 ? 7.603 72.859 -8.156 1.00 25.05 ? 229 THR D N 1 ATOM 6255 C CA . THR D 4 230 ? 6.773 71.658 -8.161 1.00 23.83 ? 229 THR D CA 1 ATOM 6256 C C . THR D 4 230 ? 5.621 71.881 -7.197 1.00 23.57 ? 229 THR D C 1 ATOM 6257 O O . THR D 4 230 ? 5.845 72.158 -6.010 1.00 23.98 ? 229 THR D O 1 ATOM 6258 C CB . THR D 4 230 ? 7.599 70.436 -7.693 1.00 23.95 ? 229 THR D CB 1 ATOM 6259 O OG1 . THR D 4 230 ? 8.702 70.239 -8.594 1.00 25.21 ? 229 THR D OG1 1 ATOM 6260 C CG2 . THR D 4 230 ? 6.745 69.170 -7.617 1.00 22.61 ? 229 THR D CG2 1 ATOM 6261 N N . GLN D 4 231 ? 4.397 71.772 -7.709 1.00 22.54 ? 230 GLN D N 1 ATOM 6262 C CA . GLN D 4 231 ? 3.203 72.137 -6.959 1.00 21.09 ? 230 GLN D CA 1 ATOM 6263 C C . GLN D 4 231 ? 1.951 71.487 -7.536 1.00 21.44 ? 230 GLN D C 1 ATOM 6264 O O . GLN D 4 231 ? 1.958 70.972 -8.670 1.00 21.73 ? 230 GLN D O 1 ATOM 6265 C CB . GLN D 4 231 ? 3.033 73.653 -6.984 1.00 21.07 ? 230 GLN D CB 1 ATOM 6266 C CG . GLN D 4 231 ? 2.560 74.203 -8.301 1.00 21.14 ? 230 GLN D CG 1 ATOM 6267 C CD . GLN D 4 231 ? 2.681 75.691 -8.360 1.00 21.95 ? 230 GLN D CD 1 ATOM 6268 O OE1 . GLN D 4 231 ? 3.759 76.209 -8.630 1.00 24.12 ? 230 GLN D OE1 1 ATOM 6269 N NE2 . GLN D 4 231 ? 1.583 76.401 -8.111 1.00 20.91 ? 230 GLN D NE2 1 ATOM 6270 N N . ILE D 4 232 ? 0.873 71.534 -6.756 1.00 20.43 ? 231 ILE D N 1 ATOM 6271 C CA . ILE D 4 232 ? -0.431 71.065 -7.199 1.00 19.35 ? 231 ILE D CA 1 ATOM 6272 C C . ILE D 4 232 ? -1.325 72.271 -7.441 1.00 19.98 ? 231 ILE D C 1 ATOM 6273 O O . ILE D 4 232 ? -1.431 73.151 -6.589 1.00 20.12 ? 231 ILE D O 1 ATOM 6274 C CB . ILE D 4 232 ? -1.111 70.222 -6.136 1.00 18.31 ? 231 ILE D CB 1 ATOM 6275 C CG1 . ILE D 4 232 ? -0.374 68.907 -5.934 1.00 18.01 ? 231 ILE D CG1 1 ATOM 6276 C CG2 . ILE D 4 232 ? -2.529 69.949 -6.538 1.00 18.84 ? 231 ILE D CG2 1 ATOM 6277 C CD1 . ILE D 4 232 ? -1.037 68.010 -4.925 1.00 17.73 ? 231 ILE D CD1 1 ATOM 6278 N N . VAL D 4 233 ? -1.968 72.313 -8.600 1.00 19.84 ? 232 VAL D N 1 ATOM 6279 C CA . VAL D 4 233 ? -2.987 73.321 -8.865 1.00 19.88 ? 232 VAL D CA 1 ATOM 6280 C C . VAL D 4 233 ? -4.269 72.570 -9.187 1.00 19.68 ? 232 VAL D C 1 ATOM 6281 O O . VAL D 4 233 ? -4.231 71.557 -9.885 1.00 19.64 ? 232 VAL D O 1 ATOM 6282 C CB . VAL D 4 233 ? -2.578 74.266 -10.031 1.00 20.01 ? 232 VAL D CB 1 ATOM 6283 C CG1 . VAL D 4 233 ? -3.584 75.391 -10.198 1.00 19.53 ? 232 VAL D CG1 1 ATOM 6284 C CG2 . VAL D 4 233 ? -1.182 74.833 -9.803 1.00 19.18 ? 232 VAL D CG2 1 ATOM 6285 N N . SER D 4 234 ? -5.397 73.055 -8.674 1.00 20.31 ? 233 SER D N 1 ATOM 6286 C CA . SER D 4 234 ? -6.666 72.335 -8.804 1.00 20.94 ? 233 SER D CA 1 ATOM 6287 C C . SER D 4 234 ? -7.919 73.228 -8.907 1.00 21.20 ? 233 SER D C 1 ATOM 6288 O O . SER D 4 234 ? -7.898 74.404 -8.576 1.00 21.34 ? 233 SER D O 1 ATOM 6289 C CB . SER D 4 234 ? -6.813 71.341 -7.654 1.00 21.10 ? 233 SER D CB 1 ATOM 6290 O OG . SER D 4 234 ? -7.445 71.959 -6.553 1.00 22.45 ? 233 SER D OG 1 ATOM 6291 N N . ALA D 4 235 ? -9.006 72.649 -9.392 1.00 22.05 ? 234 ALA D N 1 ATOM 6292 C CA . ALA D 4 235 ? -10.271 73.353 -9.526 1.00 23.31 ? 234 ALA D CA 1 ATOM 6293 C C . ALA D 4 235 ? -11.327 72.384 -9.046 1.00 25.59 ? 234 ALA D C 1 ATOM 6294 O O . ALA D 4 235 ? -11.144 71.161 -9.151 1.00 25.65 ? 234 ALA D O 1 ATOM 6295 C CB . ALA D 4 235 ? -10.523 73.755 -10.971 1.00 21.60 ? 234 ALA D CB 1 ATOM 6296 N N . GLU D 4 236 ? -12.420 72.918 -8.505 1.00 27.82 ? 235 GLU D N 1 ATOM 6297 C CA . GLU D 4 236 ? -13.451 72.070 -7.922 1.00 29.52 ? 235 GLU D CA 1 ATOM 6298 C C . GLU D 4 236 ? -14.859 72.620 -8.087 1.00 29.84 ? 235 GLU D C 1 ATOM 6299 O O . GLU D 4 236 ? -15.032 73.804 -8.326 1.00 31.45 ? 235 GLU D O 1 ATOM 6300 C CB . GLU D 4 236 ? -13.134 71.811 -6.452 1.00 32.00 ? 235 GLU D CB 1 ATOM 6301 C CG . GLU D 4 236 ? -12.815 73.054 -5.647 1.00 33.50 ? 235 GLU D CG 1 ATOM 6302 C CD . GLU D 4 236 ? -14.058 73.829 -5.285 1.00 36.32 ? 235 GLU D CD 1 ATOM 6303 O OE1 . GLU D 4 236 ? -15.059 73.192 -4.884 1.00 37.53 ? 235 GLU D OE1 1 ATOM 6304 O OE2 . GLU D 4 236 ? -14.038 75.075 -5.412 1.00 39.36 ? 235 GLU D OE2 1 ATOM 6305 N N . ALA D 4 237 ? -15.854 71.741 -7.972 1.00 29.34 ? 236 ALA D N 1 ATOM 6306 C CA . ALA D 4 237 ? -17.275 72.099 -8.021 1.00 27.67 ? 236 ALA D CA 1 ATOM 6307 C C . ALA D 4 237 ? -18.095 71.078 -7.226 1.00 27.87 ? 236 ALA D C 1 ATOM 6308 O O . ALA D 4 237 ? -17.670 69.940 -7.031 1.00 27.27 ? 236 ALA D O 1 ATOM 6309 C CB . ALA D 4 237 ? -17.759 72.155 -9.456 1.00 26.25 ? 236 ALA D CB 1 ATOM 6310 N N . TRP D 4 238 ? -19.272 71.483 -6.764 1.00 29.01 ? 237 TRP D N 1 ATOM 6311 C CA . TRP D 4 238 ? -20.202 70.542 -6.138 1.00 29.57 ? 237 TRP D CA 1 ATOM 6312 C C . TRP D 4 238 ? -21.275 70.167 -7.104 1.00 31.01 ? 237 TRP D C 1 ATOM 6313 O O . TRP D 4 238 ? -21.694 70.975 -7.943 1.00 29.91 ? 237 TRP D O 1 ATOM 6314 C CB . TRP D 4 238 ? -20.833 71.147 -4.899 1.00 28.09 ? 237 TRP D CB 1 ATOM 6315 C CG . TRP D 4 238 ? -19.863 71.300 -3.771 1.00 27.39 ? 237 TRP D CG 1 ATOM 6316 C CD1 . TRP D 4 238 ? -18.980 72.349 -3.550 1.00 27.32 ? 237 TRP D CD1 1 ATOM 6317 C CD2 . TRP D 4 238 ? -19.636 70.364 -2.662 1.00 27.94 ? 237 TRP D CD2 1 ATOM 6318 N NE1 . TRP D 4 238 ? -18.246 72.140 -2.407 1.00 27.58 ? 237 TRP D NE1 1 ATOM 6319 C CE2 . TRP D 4 238 ? -18.587 70.967 -1.825 1.00 28.09 ? 237 TRP D CE2 1 ATOM 6320 C CE3 . TRP D 4 238 ? -20.182 69.134 -2.283 1.00 27.63 ? 237 TRP D CE3 1 ATOM 6321 C CZ2 . TRP D 4 238 ? -18.116 70.345 -0.668 1.00 27.78 ? 237 TRP D CZ2 1 ATOM 6322 C CZ3 . TRP D 4 238 ? -19.701 68.520 -1.116 1.00 27.32 ? 237 TRP D CZ3 1 ATOM 6323 C CH2 . TRP D 4 238 ? -18.684 69.109 -0.333 1.00 27.07 ? 237 TRP D CH2 1 ATOM 6324 N N . GLY D 4 239 ? -21.737 68.932 -7.005 1.00 33.04 ? 238 GLY D N 1 ATOM 6325 C CA . GLY D 4 239 ? -22.913 68.536 -7.763 1.00 36.84 ? 238 GLY D CA 1 ATOM 6326 C C . GLY D 4 239 ? -24.084 69.427 -7.391 1.00 39.27 ? 238 GLY D C 1 ATOM 6327 O O . GLY D 4 239 ? -24.165 69.894 -6.249 1.00 37.08 ? 238 GLY D O 1 ATOM 6328 N N . ARG D 4 240 ? -24.977 69.661 -8.358 1.00 43.56 ? 239 ARG D N 1 ATOM 6329 C CA . ARG D 4 240 ? -26.165 70.513 -8.179 1.00 44.22 ? 239 ARG D CA 1 ATOM 6330 C C . ARG D 4 240 ? -27.393 69.976 -8.928 1.00 47.15 ? 239 ARG D C 1 ATOM 6331 O O . ARG D 4 240 ? -27.264 69.363 -9.996 1.00 46.97 ? 239 ARG D O 1 ATOM 6332 C CB . ARG D 4 240 ? -25.862 71.945 -8.626 1.00 43.56 ? 239 ARG D CB 1 ATOM 6333 C CG . ARG D 4 240 ? -25.538 72.092 -10.114 1.00 46.27 ? 239 ARG D CG 1 ATOM 6334 C CD . ARG D 4 240 ? -24.851 73.417 -10.426 1.00 49.02 ? 239 ARG D CD 1 ATOM 6335 N NE . ARG D 4 240 ? -23.430 73.361 -10.075 1.00 52.29 ? 239 ARG D NE 1 ATOM 6336 C CZ . ARG D 4 240 ? -22.901 73.871 -8.962 1.00 56.08 ? 239 ARG D CZ 1 ATOM 6337 N NH1 . ARG D 4 240 ? -23.670 74.497 -8.078 1.00 60.15 ? 239 ARG D NH1 1 ATOM 6338 N NH2 . ARG D 4 240 ? -21.595 73.765 -8.730 1.00 55.57 ? 239 ARG D NH2 1 ATOM 6339 N N . ALA D 4 241 ? -28.579 70.223 -8.367 1.00 49.44 ? 240 ALA D N 1 ATOM 6340 C CA . ALA D 4 241 ? -29.844 69.793 -8.975 1.00 48.41 ? 240 ALA D CA 1 ATOM 6341 C C . ALA D 4 241 ? -30.519 70.950 -9.695 1.00 48.36 ? 240 ALA D C 1 ATOM 6342 O O . ALA D 4 241 ? -30.014 71.434 -10.708 1.00 48.63 ? 240 ALA D O 1 ATOM 6343 C CB . ALA D 4 241 ? -30.775 69.194 -7.927 1.00 47.10 ? 240 ALA D CB 1 HETATM 6344 C C1 . NAG E 5 . ? 45.554 41.708 -17.641 1.00 58.28 ? 301 NAG A C1 1 HETATM 6345 C C2 . NAG E 5 . ? 46.020 43.052 -18.238 1.00 67.37 ? 301 NAG A C2 1 HETATM 6346 C C3 . NAG E 5 . ? 47.071 42.916 -19.352 1.00 68.63 ? 301 NAG A C3 1 HETATM 6347 C C4 . NAG E 5 . ? 48.120 41.831 -19.084 1.00 67.27 ? 301 NAG A C4 1 HETATM 6348 C C5 . NAG E 5 . ? 47.412 40.535 -18.664 1.00 63.36 ? 301 NAG A C5 1 HETATM 6349 C C6 . NAG E 5 . ? 48.364 39.336 -18.496 1.00 58.71 ? 301 NAG A C6 1 HETATM 6350 C C7 . NAG E 5 . ? 44.315 44.828 -18.020 1.00 74.21 ? 301 NAG A C7 1 HETATM 6351 C C8 . NAG E 5 . ? 43.169 45.529 -18.699 1.00 68.14 ? 301 NAG A C8 1 HETATM 6352 N N2 . NAG E 5 . ? 44.894 43.842 -18.729 1.00 69.82 ? 301 NAG A N2 1 HETATM 6353 O O3 . NAG E 5 . ? 47.734 44.149 -19.504 1.00 70.60 ? 301 NAG A O3 1 HETATM 6354 O O4 . NAG E 5 . ? 48.931 41.649 -20.232 1.00 67.26 ? 301 NAG A O4 1 HETATM 6355 O O5 . NAG E 5 . ? 46.655 40.803 -17.484 1.00 60.92 ? 301 NAG A O5 1 HETATM 6356 O O6 . NAG E 5 . ? 49.133 39.425 -17.318 1.00 53.56 ? 301 NAG A O6 1 HETATM 6357 O O7 . NAG E 5 . ? 44.664 45.170 -16.876 1.00 71.38 ? 301 NAG A O7 1 HETATM 6358 C C1 . NAG F 5 . ? 40.551 33.459 -25.623 1.00 37.76 ? 302 NAG A C1 1 HETATM 6359 C C2 . NAG F 5 . ? 41.172 34.846 -25.765 1.00 39.33 ? 302 NAG A C2 1 HETATM 6360 C C3 . NAG F 5 . ? 40.154 35.978 -25.627 1.00 43.49 ? 302 NAG A C3 1 HETATM 6361 C C4 . NAG F 5 . ? 38.945 35.752 -26.534 1.00 46.92 ? 302 NAG A C4 1 HETATM 6362 C C5 . NAG F 5 . ? 38.413 34.345 -26.246 1.00 45.88 ? 302 NAG A C5 1 HETATM 6363 C C6 . NAG F 5 . ? 37.193 34.013 -27.099 1.00 45.79 ? 302 NAG A C6 1 HETATM 6364 C C7 . NAG F 5 . ? 43.431 35.188 -25.003 1.00 37.34 ? 302 NAG A C7 1 HETATM 6365 C C8 . NAG F 5 . ? 44.345 35.353 -23.828 1.00 36.10 ? 302 NAG A C8 1 HETATM 6366 N N2 . NAG F 5 . ? 42.146 35.021 -24.727 1.00 36.86 ? 302 NAG A N2 1 HETATM 6367 O O3 . NAG F 5 . ? 40.778 37.217 -25.899 1.00 43.87 ? 302 NAG A O3 1 HETATM 6368 O O4 . NAG F 5 . ? 37.946 36.735 -26.307 1.00 55.69 ? 302 NAG A O4 1 HETATM 6369 O O5 . NAG F 5 . ? 39.424 33.367 -26.471 1.00 41.70 ? 302 NAG A O5 1 HETATM 6370 O O6 . NAG F 5 . ? 37.630 33.686 -28.393 1.00 48.91 ? 302 NAG A O6 1 HETATM 6371 O O7 . NAG F 5 . ? 43.887 35.197 -26.143 1.00 37.10 ? 302 NAG A O7 1 HETATM 6372 C C1 . NAG G 5 . ? 37.707 37.497 -27.509 1.00 63.46 ? 303 NAG A C1 1 HETATM 6373 C C2 . NAG G 5 . ? 36.354 38.226 -27.461 1.00 68.32 ? 303 NAG A C2 1 HETATM 6374 C C3 . NAG G 5 . ? 36.185 39.299 -28.544 1.00 73.78 ? 303 NAG A C3 1 HETATM 6375 C C4 . NAG G 5 . ? 37.482 40.023 -28.942 1.00 75.64 ? 303 NAG A C4 1 HETATM 6376 C C5 . NAG G 5 . ? 38.635 39.013 -29.035 1.00 72.36 ? 303 NAG A C5 1 HETATM 6377 C C6 . NAG G 5 . ? 39.989 39.605 -29.410 1.00 72.71 ? 303 NAG A C6 1 HETATM 6378 C C7 . NAG G 5 . ? 34.656 36.670 -26.661 1.00 67.56 ? 303 NAG A C7 1 HETATM 6379 C C8 . NAG G 5 . ? 33.564 35.707 -27.037 1.00 63.20 ? 303 NAG A C8 1 HETATM 6380 N N2 . NAG G 5 . ? 35.278 37.277 -27.666 1.00 68.00 ? 303 NAG A N2 1 HETATM 6381 O O3 . NAG G 5 . ? 35.226 40.226 -28.090 1.00 75.81 ? 303 NAG A O3 1 HETATM 6382 O O4 . NAG G 5 . ? 37.276 40.719 -30.160 1.00 74.49 ? 303 NAG A O4 1 HETATM 6383 O O5 . NAG G 5 . ? 38.766 38.393 -27.772 1.00 68.24 ? 303 NAG A O5 1 HETATM 6384 O O6 . NAG G 5 . ? 40.950 38.566 -29.408 1.00 71.20 ? 303 NAG A O6 1 HETATM 6385 O O7 . NAG G 5 . ? 34.950 36.867 -25.482 1.00 66.35 ? 303 NAG A O7 1 HETATM 6386 C C1 . NAG H 5 . ? 21.485 11.210 -12.651 1.00 33.01 ? 304 NAG A C1 1 HETATM 6387 C C2 . NAG H 5 . ? 20.005 11.442 -12.371 1.00 34.07 ? 304 NAG A C2 1 HETATM 6388 C C3 . NAG H 5 . ? 19.846 11.977 -10.954 1.00 35.60 ? 304 NAG A C3 1 HETATM 6389 C C4 . NAG H 5 . ? 20.518 11.070 -9.916 1.00 37.96 ? 304 NAG A C4 1 HETATM 6390 C C5 . NAG H 5 . ? 21.986 10.851 -10.297 1.00 39.08 ? 304 NAG A C5 1 HETATM 6391 C C6 . NAG H 5 . ? 22.677 9.788 -9.435 1.00 43.01 ? 304 NAG A C6 1 HETATM 6392 C C7 . NAG H 5 . ? 19.045 12.117 -14.571 1.00 34.33 ? 304 NAG A C7 1 HETATM 6393 C C8 . NAG H 5 . ? 18.519 13.277 -15.365 1.00 32.19 ? 304 NAG A C8 1 HETATM 6394 N N2 . NAG H 5 . ? 19.452 12.394 -13.318 1.00 34.14 ? 304 NAG A N2 1 HETATM 6395 O O3 . NAG H 5 . ? 18.479 12.090 -10.672 1.00 35.15 ? 304 NAG A O3 1 HETATM 6396 O O4 . NAG H 5 . ? 20.477 11.699 -8.657 1.00 40.59 ? 304 NAG A O4 1 HETATM 6397 O O5 . NAG H 5 . ? 22.103 10.425 -11.649 1.00 37.22 ? 304 NAG A O5 1 HETATM 6398 O O6 . NAG H 5 . ? 23.885 10.246 -8.838 1.00 51.56 ? 304 NAG A O6 1 HETATM 6399 O O7 . NAG H 5 . ? 19.083 10.999 -15.098 1.00 33.77 ? 304 NAG A O7 1 HETATM 6400 C C1 . NAG I 5 . ? 19.493 11.178 -7.745 1.00 42.58 ? 305 NAG A C1 1 HETATM 6401 C C2 . NAG I 5 . ? 19.976 11.500 -6.323 1.00 43.40 ? 305 NAG A C2 1 HETATM 6402 C C3 . NAG I 5 . ? 18.890 11.324 -5.253 1.00 43.43 ? 305 NAG A C3 1 HETATM 6403 C C4 . NAG I 5 . ? 17.550 11.935 -5.665 1.00 44.81 ? 305 NAG A C4 1 HETATM 6404 C C5 . NAG I 5 . ? 17.197 11.393 -7.055 1.00 44.55 ? 305 NAG A C5 1 HETATM 6405 C C6 . NAG I 5 . ? 15.837 11.873 -7.558 1.00 42.32 ? 305 NAG A C6 1 HETATM 6406 C C7 . NAG I 5 . ? 22.248 11.128 -5.416 1.00 41.68 ? 305 NAG A C7 1 HETATM 6407 C C8 . NAG I 5 . ? 23.304 10.086 -5.175 1.00 45.01 ? 305 NAG A C8 1 HETATM 6408 N N2 . NAG I 5 . ? 21.128 10.676 -5.996 1.00 42.00 ? 305 NAG A N2 1 HETATM 6409 O O3 . NAG I 5 . ? 19.329 11.947 -4.076 1.00 43.03 ? 305 NAG A O3 1 HETATM 6410 O O4 . NAG I 5 . ? 16.549 11.649 -4.699 1.00 46.16 ? 305 NAG A O4 1 HETATM 6411 O O5 . NAG I 5 . ? 18.222 11.762 -7.979 1.00 44.59 ? 305 NAG A O5 1 HETATM 6412 O O6 . NAG I 5 . ? 16.017 12.778 -8.624 1.00 38.67 ? 305 NAG A O6 1 HETATM 6413 O O7 . NAG I 5 . ? 22.466 12.293 -5.081 1.00 37.97 ? 305 NAG A O7 1 HETATM 6414 C C1 . FUL J 6 . ? 24.923 10.546 -9.807 1.00 54.62 ? 306 FUL A C1 1 HETATM 6415 C C2 . FUL J 6 . ? 26.227 9.776 -9.617 1.00 55.93 ? 306 FUL A C2 1 HETATM 6416 O O2 . FUL J 6 . ? 25.968 8.420 -9.249 1.00 60.08 ? 306 FUL A O2 1 HETATM 6417 C C3 . FUL J 6 . ? 26.978 9.927 -10.953 1.00 55.47 ? 306 FUL A C3 1 HETATM 6418 O O3 . FUL J 6 . ? 28.122 9.072 -11.097 1.00 51.80 ? 306 FUL A O3 1 HETATM 6419 C C4 . FUL J 6 . ? 27.368 11.393 -11.130 1.00 55.22 ? 306 FUL A C4 1 HETATM 6420 O O4 . FUL J 6 . ? 28.401 11.763 -10.201 1.00 53.60 ? 306 FUL A O4 1 HETATM 6421 C C5 . FUL J 6 . ? 26.126 12.289 -10.963 1.00 55.93 ? 306 FUL A C5 1 HETATM 6422 C C6 . FUL J 6 . ? 26.517 13.744 -10.777 1.00 55.16 ? 306 FUL A C6 1 HETATM 6423 O O5 . FUL J 6 . ? 25.301 11.925 -9.842 1.00 57.29 ? 306 FUL A O5 1 HETATM 6424 C CAZ . 1LA K 7 . ? 31.105 16.301 -19.149 1.00 41.81 ? 307 1LA A CAZ 1 HETATM 6425 C CAY . 1LA K 7 . ? 31.577 14.958 -19.730 1.00 39.73 ? 307 1LA A CAY 1 HETATM 6426 C CAX . 1LA K 7 . ? 31.936 15.130 -21.211 1.00 37.67 ? 307 1LA A CAX 1 HETATM 6427 C CAW . 1LA K 7 . ? 30.875 14.459 -22.096 1.00 35.65 ? 307 1LA A CAW 1 HETATM 6428 C CAV . 1LA K 7 . ? 31.560 13.636 -23.195 1.00 35.08 ? 307 1LA A CAV 1 HETATM 6429 C CAU . 1LA K 7 . ? 31.838 14.494 -24.444 1.00 34.13 ? 307 1LA A CAU 1 HETATM 6430 C CAT . 1LA K 7 . ? 33.340 14.489 -24.759 1.00 31.49 ? 307 1LA A CAT 1 HETATM 6431 C CAS . 1LA K 7 . ? 33.652 15.629 -25.716 1.00 28.98 ? 307 1LA A CAS 1 HETATM 6432 C CAR . 1LA K 7 . ? 35.121 16.002 -25.586 1.00 28.06 ? 307 1LA A CAR 1 HETATM 6433 C CAQ . 1LA K 7 . ? 35.257 17.530 -25.617 1.00 27.89 ? 307 1LA A CAQ 1 HETATM 6434 C CAP . 1LA K 7 . ? 35.604 18.063 -24.226 1.00 26.41 ? 307 1LA A CAP 1 HETATM 6435 C CAO . 1LA K 7 . ? 35.410 19.577 -24.174 1.00 26.06 ? 307 1LA A CAO 1 HETATM 6436 C CAN . 1LA K 7 . ? 36.173 20.191 -22.978 1.00 26.91 ? 307 1LA A CAN 1 HETATM 6437 C CAM . 1LA K 7 . ? 35.656 19.647 -21.624 1.00 26.98 ? 307 1LA A CAM 1 HETATM 6438 C CAL . 1LA K 7 . ? 35.613 20.748 -20.563 1.00 26.46 ? 307 1LA A CAL 1 HETATM 6439 C CAK . 1LA K 7 . ? 35.002 20.196 -19.268 1.00 26.53 ? 307 1LA A CAK 1 HETATM 6440 C CAJ . 1LA K 7 . ? 33.618 20.830 -19.112 1.00 26.80 ? 307 1LA A CAJ 1 HETATM 6441 C CAI . 1LA K 7 . ? 32.684 20.055 -18.167 1.00 26.24 ? 307 1LA A CAI 1 HETATM 6442 C CAH . 1LA K 7 . ? 31.243 20.233 -18.702 1.00 26.31 ? 307 1LA A CAH 1 HETATM 6443 C CAG . 1LA K 7 . ? 30.230 20.504 -17.582 1.00 25.06 ? 307 1LA A CAG 1 HETATM 6444 C CAF . 1LA K 7 . ? 29.571 21.876 -17.751 1.00 23.75 ? 307 1LA A CAF 1 HETATM 6445 C CAE . 1LA K 7 . ? 28.464 21.813 -18.813 1.00 23.41 ? 307 1LA A CAE 1 HETATM 6446 C CAD . 1LA K 7 . ? 27.464 22.955 -18.591 1.00 22.41 ? 307 1LA A CAD 1 HETATM 6447 C CAC . 1LA K 7 . ? 26.507 23.038 -19.782 1.00 22.24 ? 307 1LA A CAC 1 HETATM 6448 C CAB . 1LA K 7 . ? 25.339 23.991 -19.487 1.00 22.19 ? 307 1LA A CAB 1 HETATM 6449 C CAA . 1LA K 7 . ? 25.720 25.437 -19.812 1.00 22.44 ? 307 1LA A CAA 1 HETATM 6450 O OAA . 1LA K 7 . ? 26.174 25.741 -20.918 1.00 22.13 ? 307 1LA A OAA 1 HETATM 6451 N N2 . 1LA K 7 . ? 25.523 26.316 -18.811 1.00 23.22 ? 307 1LA A N2 1 HETATM 6452 C C2 . 1LA K 7 . ? 25.925 27.728 -18.957 1.00 24.28 ? 307 1LA A C2 1 HETATM 6453 C C3 . 1LA K 7 . ? 25.966 28.399 -17.590 1.00 24.65 ? 307 1LA A C3 1 HETATM 6454 O O3 . 1LA K 7 . ? 26.380 29.733 -17.782 1.00 25.53 ? 307 1LA A O3 1 HETATM 6455 C C4 . 1LA K 7 . ? 26.916 27.748 -16.569 1.00 26.03 ? 307 1LA A C4 1 HETATM 6456 O O4 . 1LA K 7 . ? 26.933 28.576 -15.387 1.00 25.86 ? 307 1LA A O4 1 HETATM 6457 C C5 . 1LA K 7 . ? 28.357 27.572 -17.101 1.00 26.36 ? 307 1LA A C5 1 HETATM 6458 C C6 . 1LA K 7 . ? 29.325 27.217 -15.949 1.00 26.29 ? 307 1LA A C6 1 HETATM 6459 C C7 . 1LA K 7 . ? 29.136 25.764 -15.482 1.00 26.54 ? 307 1LA A C7 1 HETATM 6460 C C8 . 1LA K 7 . ? 30.395 25.269 -14.741 1.00 26.26 ? 307 1LA A C8 1 HETATM 6461 C C9 . 1LA K 7 . ? 30.238 25.507 -13.229 1.00 25.47 ? 307 1LA A C9 1 HETATM 6462 C C10 . 1LA K 7 . ? 31.561 25.228 -12.502 1.00 25.02 ? 307 1LA A C10 1 HETATM 6463 C C11 . 1LA K 7 . ? 31.474 25.707 -11.052 1.00 24.24 ? 307 1LA A C11 1 HETATM 6464 C C12 . 1LA K 7 . ? 32.514 26.789 -10.803 1.00 23.21 ? 307 1LA A C12 1 HETATM 6465 C C13 . 1LA K 7 . ? 32.399 27.369 -9.387 1.00 23.36 ? 307 1LA A C13 1 HETATM 6466 C C14 . 1LA K 7 . ? 33.243 28.655 -9.399 1.00 24.13 ? 307 1LA A C14 1 HETATM 6467 C C15 . 1LA K 7 . ? 33.452 29.260 -8.011 1.00 24.10 ? 307 1LA A C15 1 HETATM 6468 C C16 . 1LA K 7 . ? 33.314 30.792 -8.148 1.00 24.34 ? 307 1LA A C16 1 HETATM 6469 C C17 . 1LA K 7 . ? 34.665 31.531 -8.009 1.00 24.29 ? 307 1LA A C17 1 HETATM 6470 C C18 . 1LA K 7 . ? 34.443 33.044 -7.767 1.00 23.30 ? 307 1LA A C18 1 HETATM 6471 C C1 . 1LA K 7 . ? 24.940 28.488 -19.868 1.00 25.12 ? 307 1LA A C1 1 HETATM 6472 O O1A . 1LA K 7 . ? 23.608 28.116 -19.491 1.00 25.76 ? 307 1LA A O1A 1 HETATM 6473 C C1A . 1LA K 7 . ? 22.601 28.812 -20.210 1.00 25.47 ? 307 1LA A C1A 1 HETATM 6474 O O6A . 1LA K 7 . ? 22.318 28.096 -21.474 1.00 26.40 ? 307 1LA A O6A 1 HETATM 6475 C C2A . 1LA K 7 . ? 21.359 28.842 -19.324 1.00 25.34 ? 307 1LA A C2A 1 HETATM 6476 O O2A . 1LA K 7 . ? 21.639 29.429 -18.043 1.00 24.35 ? 307 1LA A O2A 1 HETATM 6477 C C3A . 1LA K 7 . ? 20.871 27.421 -19.084 1.00 25.81 ? 307 1LA A C3A 1 HETATM 6478 O O3A . 1LA K 7 . ? 19.643 27.497 -18.393 1.00 27.01 ? 307 1LA A O3A 1 HETATM 6479 C C4A . 1LA K 7 . ? 20.671 26.682 -20.406 1.00 26.73 ? 307 1LA A C4A 1 HETATM 6480 O O4A . 1LA K 7 . ? 19.654 27.328 -21.143 1.00 25.14 ? 307 1LA A O4A 1 HETATM 6481 C C5M . 1LA K 7 . ? 22.021 26.734 -21.163 1.00 27.76 ? 307 1LA A C5M 1 HETATM 6482 C C6A . 1LA K 7 . ? 22.144 25.690 -22.300 1.00 30.87 ? 307 1LA A C6A 1 HETATM 6483 O OAZ . 1LA K 7 . ? 21.380 26.024 -23.467 1.00 34.11 ? 307 1LA A OAZ 1 HETATM 6484 C CCI . 1LA K 7 . ? 20.536 24.992 -23.775 1.00 37.15 ? 307 1LA A CCI 1 HETATM 6485 O OCK . 1LA K 7 . ? 19.880 24.444 -22.879 1.00 38.56 ? 307 1LA A OCK 1 HETATM 6486 N NCJ . 1LA K 7 . ? 20.426 24.600 -25.062 1.00 39.75 ? 307 1LA A NCJ 1 HETATM 6487 C CCU . 1LA K 7 . ? 19.584 23.597 -25.461 1.00 43.12 ? 307 1LA A CCU 1 HETATM 6488 C CCL . 1LA K 7 . ? 18.785 22.842 -24.575 1.00 43.13 ? 307 1LA A CCL 1 HETATM 6489 C CCQ . 1LA K 7 . ? 17.941 21.835 -25.059 1.00 44.78 ? 307 1LA A CCQ 1 HETATM 6490 N N . 1LA K 7 . ? 17.879 21.559 -26.451 1.00 43.24 ? 307 1LA A N 1 HETATM 6491 C CCS . 1LA K 7 . ? 18.680 22.304 -27.335 1.00 43.08 ? 307 1LA A CCS 1 HETATM 6492 C CCT . 1LA K 7 . ? 19.510 23.313 -26.840 1.00 42.99 ? 307 1LA A CCT 1 HETATM 6493 O O . HOH L 8 . ? 36.270 -3.498 -11.927 1.00 35.80 ? 401 HOH A O 1 HETATM 6494 O O . HOH L 8 . ? 53.261 8.757 -23.484 1.00 30.70 ? 402 HOH A O 1 HETATM 6495 O O . HOH L 8 . ? 32.625 12.449 -6.789 1.00 31.54 ? 403 HOH A O 1 HETATM 6496 O O . HOH L 8 . ? 39.368 11.221 -11.226 1.00 22.20 ? 404 HOH A O 1 HETATM 6497 O O . HOH L 8 . ? 31.086 7.304 -28.959 1.00 31.00 ? 405 HOH A O 1 HETATM 6498 O O . HOH L 8 . ? 55.463 7.607 -11.708 1.00 29.77 ? 406 HOH A O 1 HETATM 6499 O O . HOH L 8 . ? 48.881 12.964 -30.237 1.00 30.34 ? 407 HOH A O 1 HETATM 6500 O O . HOH L 8 . ? 77.982 -10.854 -14.491 1.00 42.02 ? 408 HOH A O 1 HETATM 6501 O O . HOH L 8 . ? 41.127 43.534 -12.670 1.00 24.46 ? 409 HOH A O 1 HETATM 6502 O O . HOH L 8 . ? 43.445 32.850 -27.634 1.00 23.46 ? 410 HOH A O 1 HETATM 6503 O O . HOH L 8 . ? 35.534 40.150 -32.123 1.00 36.66 ? 411 HOH A O 1 HETATM 6504 O O . HOH L 8 . ? 39.401 31.400 -0.338 1.00 33.12 ? 412 HOH A O 1 HETATM 6505 O O . HOH L 8 . ? 58.930 2.020 -29.367 1.00 28.36 ? 413 HOH A O 1 HETATM 6506 O O . HOH L 8 . ? 40.530 37.528 -22.582 1.00 33.26 ? 414 HOH A O 1 HETATM 6507 O O . HOH L 8 . ? 60.952 -0.286 -29.601 1.00 28.53 ? 415 HOH A O 1 HETATM 6508 O O . HOH L 8 . ? 34.655 14.889 -3.107 1.00 26.94 ? 416 HOH A O 1 HETATM 6509 O O . HOH L 8 . ? 32.831 15.180 -37.870 1.00 16.61 ? 417 HOH A O 1 HETATM 6510 O O . HOH L 8 . ? 28.185 10.316 -39.169 1.00 38.49 ? 418 HOH A O 1 HETATM 6511 O O . HOH L 8 . ? 17.290 25.967 -20.130 1.00 12.88 ? 419 HOH A O 1 HETATM 6512 O O . HOH L 8 . ? 44.543 22.494 -24.794 1.00 25.27 ? 420 HOH A O 1 HETATM 6513 O O . HOH L 8 . ? 35.170 41.024 -15.133 1.00 22.69 ? 421 HOH A O 1 HETATM 6514 O O . HOH L 8 . ? 15.452 28.909 -9.833 1.00 22.32 ? 422 HOH A O 1 HETATM 6515 O O . HOH L 8 . ? 31.486 39.416 -0.047 1.00 26.54 ? 423 HOH A O 1 HETATM 6516 O O . HOH L 8 . ? 23.850 8.190 -12.654 1.00 38.46 ? 424 HOH A O 1 HETATM 6517 O O . HOH L 8 . ? 39.898 12.130 -37.023 0.50 13.33 ? 425 HOH A O 1 HETATM 6518 O O . HOH L 8 . ? 57.832 -1.697 -30.606 1.00 47.49 ? 426 HOH A O 1 HETATM 6519 O O . HOH L 8 . ? 37.674 37.771 -21.541 1.00 36.00 ? 427 HOH A O 1 HETATM 6520 O O . HOH L 8 . ? 34.561 34.366 -23.765 1.00 28.42 ? 428 HOH A O 1 HETATM 6521 O O . HOH L 8 . ? 44.306 28.201 -19.590 1.00 22.21 ? 429 HOH A O 1 HETATM 6522 O O . HOH L 8 . ? 19.605 27.807 -5.554 1.00 21.92 ? 430 HOH A O 1 HETATM 6523 O O . HOH L 8 . ? 67.796 -3.004 -24.872 1.00 41.71 ? 431 HOH A O 1 HETATM 6524 O O . HOH L 8 . ? 41.964 37.376 -2.965 1.00 34.64 ? 432 HOH A O 1 HETATM 6525 O O . HOH L 8 . ? 38.651 28.689 -35.371 1.00 36.34 ? 433 HOH A O 1 HETATM 6526 O O . HOH L 8 . ? 17.663 25.734 -6.596 1.00 30.90 ? 434 HOH A O 1 HETATM 6527 O O . HOH L 8 . ? 46.653 31.518 -12.100 1.00 33.64 ? 435 HOH A O 1 HETATM 6528 O O . HOH L 8 . ? 66.606 -12.384 -4.777 1.00 39.40 ? 436 HOH A O 1 HETATM 6529 O O . HOH L 8 . ? 48.820 -5.159 -29.695 1.00 37.66 ? 437 HOH A O 1 HETATM 6530 O O . HOH L 8 . ? 42.183 39.038 -23.782 1.00 45.91 ? 438 HOH A O 1 HETATM 6531 O O . HOH L 8 . ? 43.759 38.612 -28.758 1.00 37.92 ? 439 HOH A O 1 HETATM 6532 O O . HOH L 8 . ? 15.562 9.145 -10.070 1.00 43.50 ? 440 HOH A O 1 HETATM 6533 O O . HOH L 8 . ? 57.939 13.080 -12.555 1.00 21.46 ? 441 HOH A O 1 HETATM 6534 O O . HOH M 8 . ? 65.616 12.838 -15.386 1.00 31.65 ? 101 HOH B O 1 HETATM 6535 O O . HOH M 8 . ? 51.924 14.241 -23.645 1.00 16.85 ? 102 HOH B O 1 HETATM 6536 O O . HOH M 8 . ? 46.086 18.479 -4.613 1.00 26.60 ? 103 HOH B O 1 HETATM 6537 O O . HOH M 8 . ? 59.648 16.784 -13.941 1.00 25.25 ? 104 HOH B O 1 HETATM 6538 O O . HOH M 8 . ? 48.910 31.288 -15.265 1.00 32.00 ? 105 HOH B O 1 HETATM 6539 O O . HOH M 8 . ? 64.091 19.491 -10.720 1.00 36.40 ? 106 HOH B O 1 HETATM 6540 O O . HOH M 8 . ? 50.913 27.804 -1.622 1.00 34.84 ? 107 HOH B O 1 HETATM 6541 O O . HOH M 8 . ? 52.631 12.274 -18.138 1.00 34.21 ? 108 HOH B O 1 HETATM 6542 O O . HOH M 8 . ? 76.763 8.116 -24.807 1.00 32.35 ? 109 HOH B O 1 HETATM 6543 O O . HOH M 8 . ? 52.474 17.965 -12.016 1.00 27.42 ? 110 HOH B O 1 HETATM 6544 O O . HOH M 8 . ? 42.171 16.297 -10.873 1.00 26.93 ? 111 HOH B O 1 HETATM 6545 O O . HOH M 8 . ? 64.801 3.333 -28.893 1.00 24.62 ? 112 HOH B O 1 HETATM 6546 O O . HOH M 8 . ? 44.150 14.320 -14.577 1.00 31.36 ? 113 HOH B O 1 HETATM 6547 O O . HOH M 8 . ? 78.068 7.914 -27.431 1.00 32.14 ? 114 HOH B O 1 HETATM 6548 O O . HOH N 8 . ? 17.006 20.530 -29.278 1.00 42.41 ? 401 HOH C O 1 HETATM 6549 O O . HOH N 8 . ? -18.666 62.952 -23.269 1.00 34.87 ? 402 HOH C O 1 HETATM 6550 O O . HOH N 8 . ? 18.396 27.169 -25.718 1.00 27.41 ? 403 HOH C O 1 HETATM 6551 O O . HOH N 8 . ? 21.670 28.231 -26.844 1.00 21.10 ? 404 HOH C O 1 HETATM 6552 O O . HOH N 8 . ? -14.289 60.754 -24.303 1.00 33.30 ? 405 HOH C O 1 HETATM 6553 O O . HOH N 8 . ? -24.648 63.244 -26.978 1.00 43.78 ? 406 HOH C O 1 HETATM 6554 O O . HOH N 8 . ? 21.405 45.276 -35.302 1.00 25.79 ? 407 HOH C O 1 HETATM 6555 O O . HOH N 8 . ? -9.324 79.389 -21.302 1.00 24.78 ? 408 HOH C O 1 HETATM 6556 O O . HOH N 8 . ? 17.438 38.459 -34.900 1.00 39.45 ? 409 HOH C O 1 HETATM 6557 O O . HOH N 8 . ? -4.681 38.403 -18.707 1.00 26.85 ? 410 HOH C O 1 HETATM 6558 O O . HOH N 8 . ? -4.912 34.776 -31.621 1.00 31.61 ? 411 HOH C O 1 HETATM 6559 O O . HOH N 8 . ? -25.137 59.104 -35.512 1.00 33.49 ? 412 HOH C O 1 HETATM 6560 O O . HOH N 8 . ? -15.215 46.829 -33.399 1.00 26.04 ? 413 HOH C O 1 HETATM 6561 O O . HOH N 8 . ? 12.195 24.796 -35.743 1.00 23.96 ? 414 HOH C O 1 HETATM 6562 O O . HOH N 8 . ? -0.643 39.090 -15.988 1.00 33.66 ? 415 HOH C O 1 HETATM 6563 O O . HOH N 8 . ? 10.576 47.697 -32.469 1.00 26.64 ? 416 HOH C O 1 HETATM 6564 O O . HOH N 8 . ? -23.644 65.006 -46.950 1.00 30.92 ? 417 HOH C O 1 HETATM 6565 O O . HOH N 8 . ? 6.765 30.190 -32.163 1.00 31.39 ? 418 HOH C O 1 HETATM 6566 O O . HOH N 8 . ? 10.575 40.035 -35.596 1.00 29.22 ? 419 HOH C O 1 HETATM 6567 O O . HOH N 8 . ? -19.491 86.576 -13.366 1.00 27.30 ? 420 HOH C O 1 HETATM 6568 O O . HOH N 8 . ? 4.440 32.110 -17.569 1.00 26.60 ? 421 HOH C O 1 HETATM 6569 O O . HOH N 8 . ? 16.253 28.521 -14.066 1.00 21.12 ? 422 HOH C O 1 HETATM 6570 O O . HOH N 8 . ? -6.538 38.439 -20.361 1.00 32.77 ? 423 HOH C O 1 HETATM 6571 O O . HOH N 8 . ? -22.431 45.631 -25.638 1.00 25.75 ? 424 HOH C O 1 HETATM 6572 O O . HOH N 8 . ? 15.115 24.495 -23.031 1.00 23.99 ? 425 HOH C O 1 HETATM 6573 O O . HOH O 8 . ? 12.020 70.572 -3.512 1.00 22.71 ? 301 HOH D O 1 HETATM 6574 O O . HOH O 8 . ? -2.224 63.060 -16.843 1.00 7.54 ? 302 HOH D O 1 HETATM 6575 O O . HOH O 8 . ? -0.263 63.875 -19.204 1.00 26.87 ? 303 HOH D O 1 HETATM 6576 O O . HOH O 8 . ? 34.897 44.917 -13.509 1.00 33.34 ? 304 HOH D O 1 HETATM 6577 O O . HOH O 8 . ? 12.012 69.608 -24.278 1.00 26.88 ? 305 HOH D O 1 HETATM 6578 O O . HOH O 8 . ? 6.563 70.620 -16.142 1.00 27.07 ? 306 HOH D O 1 HETATM 6579 O O . HOH O 8 . ? 3.536 69.010 -5.257 1.00 26.54 ? 307 HOH D O 1 HETATM 6580 O O . HOH O 8 . ? -27.089 70.588 -12.767 1.00 35.51 ? 308 HOH D O 1 HETATM 6581 O O . HOH O 8 . ? 0.557 64.132 -6.903 1.00 17.50 ? 309 HOH D O 1 HETATM 6582 O O . HOH O 8 . ? 3.366 60.642 -9.218 1.00 30.18 ? 310 HOH D O 1 HETATM 6583 O O . HOH O 8 . ? -0.455 75.612 -6.568 1.00 13.63 ? 311 HOH D O 1 HETATM 6584 O O . HOH O 8 . ? 21.344 46.750 -21.681 1.00 22.77 ? 312 HOH D O 1 HETATM 6585 O O . HOH O 8 . ? 8.299 71.893 -4.267 1.00 30.40 ? 313 HOH D O 1 HETATM 6586 O O . HOH O 8 . ? 18.279 36.906 -15.679 1.00 26.08 ? 314 HOH D O 1 HETATM 6587 O O . HOH O 8 . ? 18.685 70.131 -26.109 1.00 35.67 ? 315 HOH D O 1 HETATM 6588 O O . HOH O 8 . ? 32.299 48.315 -12.636 1.00 33.57 ? 316 HOH D O 1 HETATM 6589 O O . HOH O 8 . ? 17.262 62.010 -24.627 1.00 39.36 ? 317 HOH D O 1 HETATM 6590 O O . HOH O 8 . ? 11.322 62.156 -20.304 1.00 34.61 ? 318 HOH D O 1 HETATM 6591 O O . HOH O 8 . ? -15.702 59.563 0.116 1.00 31.99 ? 319 HOH D O 1 HETATM 6592 O O . HOH O 8 . ? -29.315 62.560 -7.256 1.00 27.36 ? 320 HOH D O 1 HETATM 6593 O O . HOH O 8 . ? 18.959 45.378 -23.696 1.00 34.37 ? 321 HOH D O 1 HETATM 6594 O O . HOH O 8 . ? 18.818 47.107 -26.023 1.00 35.87 ? 322 HOH D O 1 HETATM 6595 O O . HOH O 8 . ? 10.192 64.544 -21.630 1.00 28.80 ? 323 HOH D O 1 HETATM 6596 O O . HOH O 8 . ? 7.502 79.941 -4.963 1.00 33.28 ? 324 HOH D O 1 HETATM 6597 O O . HOH O 8 . ? 3.681 39.276 -4.685 1.00 29.26 ? 325 HOH D O 1 HETATM 6598 O O . HOH O 8 . ? 10.656 68.898 -7.422 1.00 28.16 ? 326 HOH D O 1 HETATM 6599 O O . HOH O 8 . ? 32.907 53.308 -19.752 1.00 38.64 ? 327 HOH D O 1 HETATM 6600 O O . HOH O 8 . ? -24.133 72.302 -4.926 1.00 34.24 ? 328 HOH D O 1 HETATM 6601 O O . HOH O 8 . ? 12.925 77.117 -19.628 1.00 33.48 ? 329 HOH D O 1 HETATM 6602 O O . HOH O 8 . ? 4.151 53.355 -13.446 1.00 25.51 ? 330 HOH D O 1 HETATM 6603 O O . HOH O 8 . ? -26.166 74.275 -19.702 1.00 31.40 ? 331 HOH D O 1 HETATM 6604 O O . HOH O 8 . ? 9.727 65.884 -8.015 1.00 39.78 ? 332 HOH D O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 SER 1 1 ? ? ? A . n A 1 2 GLU 2 2 ? ? ? A . n A 1 3 ALA 3 3 ? ? ? A . n A 1 4 GLN 4 4 ? ? ? A . n A 1 5 GLN 5 5 ? ? ? A . n A 1 6 LYS 6 6 6 LYS LYS A . n A 1 7 ASN 7 7 7 ASN ASN A . n A 1 8 TYR 8 8 8 TYR TYR A . n A 1 9 THR 9 9 9 THR THR A . n A 1 10 PHE 10 10 10 PHE PHE A . n A 1 11 ARG 11 11 11 ARG ARG A . n A 1 12 CYS 12 12 12 CYS CYS A . n A 1 13 LEU 13 13 13 LEU LEU A . n A 1 14 GLN 14 14 14 GLN GLN A . n A 1 15 MET 15 15 15 MET MET A . n A 1 16 SER 16 16 16 SER SER A . n A 1 17 SER 17 17 17 SER SER A . n A 1 18 PHE 18 18 18 PHE PHE A . n A 1 19 ALA 19 19 19 ALA ALA A . n A 1 20 ASN 20 20 20 ASN ASN A . n A 1 21 ARG 21 21 21 ARG ARG A . n A 1 22 SER 22 22 22 SER SER A . n A 1 23 TRP 23 23 23 TRP TRP A . n A 1 24 SER 24 24 24 SER SER A . n A 1 25 ARG 25 25 25 ARG ARG A . n A 1 26 THR 26 26 26 THR THR A . n A 1 27 ASP 27 27 27 ASP ASP A . n A 1 28 SER 28 28 28 SER SER A . n A 1 29 VAL 29 29 29 VAL VAL A . n A 1 30 VAL 30 30 30 VAL VAL A . n A 1 31 TRP 31 31 31 TRP TRP A . n A 1 32 LEU 32 32 32 LEU LEU A . n A 1 33 GLY 33 33 33 GLY GLY A . n A 1 34 ASP 34 34 34 ASP ASP A . n A 1 35 LEU 35 35 35 LEU LEU A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 THR 37 37 37 THR THR A . n A 1 38 HIS 38 38 38 HIS HIS A . n A 1 39 ARG 39 39 39 ARG ARG A . n A 1 40 TRP 40 40 40 TRP TRP A . n A 1 41 SER 41 41 41 SER SER A . n A 1 42 ASN 42 42 42 ASN ASN A . n A 1 43 ASP 43 43 43 ASP ASP A . n A 1 44 SER 44 44 44 SER SER A . n A 1 45 ALA 45 45 45 ALA ALA A . n A 1 46 THR 46 46 46 THR THR A . n A 1 47 ILE 47 47 47 ILE ILE A . n A 1 48 SER 48 48 48 SER SER A . n A 1 49 PHE 49 49 49 PHE PHE A . n A 1 50 THR 50 50 50 THR THR A . n A 1 51 LYS 51 51 51 LYS LYS A . n A 1 52 PRO 52 52 52 PRO PRO A . n A 1 53 TRP 53 53 53 TRP TRP A . n A 1 54 SER 54 54 54 SER SER A . n A 1 55 GLN 55 55 55 GLN GLN A . n A 1 56 GLY 56 56 56 GLY GLY A . n A 1 57 LYS 57 57 57 LYS LYS A . n A 1 58 LEU 58 58 58 LEU LEU A . n A 1 59 SER 59 59 59 SER SER A . n A 1 60 ASN 60 60 60 ASN ASN A . n A 1 61 GLN 61 61 61 GLN GLN A . n A 1 62 GLN 62 62 62 GLN GLN A . n A 1 63 TRP 63 63 63 TRP TRP A . n A 1 64 GLU 64 64 64 GLU GLU A . n A 1 65 LYS 65 65 65 LYS LYS A . n A 1 66 LEU 66 66 66 LEU LEU A . n A 1 67 GLN 67 67 67 GLN GLN A . n A 1 68 HIS 68 68 68 HIS HIS A . n A 1 69 MET 69 69 69 MET MET A . n A 1 70 PHE 70 70 70 PHE PHE A . n A 1 71 GLN 71 71 71 GLN GLN A . n A 1 72 VAL 72 72 72 VAL VAL A . n A 1 73 TYR 73 73 73 TYR TYR A . n A 1 74 ARG 74 74 74 ARG ARG A . n A 1 75 VAL 75 75 75 VAL VAL A . n A 1 76 SER 76 76 76 SER SER A . n A 1 77 PHE 77 77 77 PHE PHE A . n A 1 78 THR 78 78 78 THR THR A . n A 1 79 ARG 79 79 79 ARG ARG A . n A 1 80 ASP 80 80 80 ASP ASP A . n A 1 81 ILE 81 81 81 ILE ILE A . n A 1 82 GLN 82 82 82 GLN GLN A . n A 1 83 GLU 83 83 83 GLU GLU A . n A 1 84 LEU 84 84 84 LEU LEU A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 LYS 86 86 86 LYS LYS A . n A 1 87 MET 87 87 87 MET MET A . n A 1 88 MET 88 88 88 MET MET A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 PRO 90 90 90 PRO PRO A . n A 1 91 LYS 91 91 91 LYS LYS A . n A 1 92 GLU 92 92 92 GLU GLU A . n A 1 93 ASP 93 93 93 ASP ASP A . n A 1 94 TYR 94 94 94 TYR TYR A . n A 1 95 PRO 95 95 95 PRO PRO A . n A 1 96 ILE 96 96 96 ILE ILE A . n A 1 97 GLU 97 97 97 GLU GLU A . n A 1 98 ILE 98 98 98 ILE ILE A . n A 1 99 GLN 99 99 99 GLN GLN A . n A 1 100 LEU 100 100 100 LEU LEU A . n A 1 101 SER 101 101 101 SER SER A . n A 1 102 ALA 102 102 102 ALA ALA A . n A 1 103 GLY 103 103 103 GLY GLY A . n A 1 104 CYS 104 104 104 CYS CYS A . n A 1 105 GLU 105 105 105 GLU GLU A . n A 1 106 MET 106 106 106 MET MET A . n A 1 107 TYR 107 107 107 TYR TYR A . n A 1 108 PRO 108 108 108 PRO PRO A . n A 1 109 GLY 109 109 109 GLY GLY A . n A 1 110 ASN 110 110 110 ASN ASN A . n A 1 111 ALA 111 111 111 ALA ALA A . n A 1 112 SER 112 112 112 SER SER A . n A 1 113 GLU 113 113 113 GLU GLU A . n A 1 114 SER 114 114 114 SER SER A . n A 1 115 PHE 115 115 115 PHE PHE A . n A 1 116 LEU 116 116 116 LEU LEU A . n A 1 117 HIS 117 117 117 HIS HIS A . n A 1 118 VAL 118 118 118 VAL VAL A . n A 1 119 ALA 119 119 119 ALA ALA A . n A 1 120 PHE 120 120 120 PHE PHE A . n A 1 121 GLN 121 121 121 GLN GLN A . n A 1 122 GLY 122 122 122 GLY GLY A . n A 1 123 LYS 123 123 123 LYS LYS A . n A 1 124 TYR 124 124 124 TYR TYR A . n A 1 125 VAL 125 125 125 VAL VAL A . n A 1 126 VAL 126 126 126 VAL VAL A . n A 1 127 ARG 127 127 127 ARG ARG A . n A 1 128 PHE 128 128 128 PHE PHE A . n A 1 129 TRP 129 129 129 TRP TRP A . n A 1 130 GLY 130 130 130 GLY GLY A . n A 1 131 THR 131 131 131 THR THR A . n A 1 132 SER 132 132 132 SER SER A . n A 1 133 TRP 133 133 133 TRP TRP A . n A 1 134 GLN 134 134 134 GLN GLN A . n A 1 135 THR 135 135 135 THR THR A . n A 1 136 VAL 136 136 136 VAL VAL A . n A 1 137 PRO 137 137 137 PRO PRO A . n A 1 138 GLY 138 138 138 GLY GLY A . n A 1 139 ALA 139 139 139 ALA ALA A . n A 1 140 PRO 140 140 140 PRO PRO A . n A 1 141 SER 141 141 141 SER SER A . n A 1 142 TRP 142 142 142 TRP TRP A . n A 1 143 LEU 143 143 143 LEU LEU A . n A 1 144 ASP 144 144 144 ASP ASP A . n A 1 145 LEU 145 145 145 LEU LEU A . n A 1 146 PRO 146 146 146 PRO PRO A . n A 1 147 ILE 147 147 147 ILE ILE A . n A 1 148 LYS 148 148 148 LYS LYS A . n A 1 149 VAL 149 149 149 VAL VAL A . n A 1 150 LEU 150 150 150 LEU LEU A . n A 1 151 ASN 151 151 151 ASN ASN A . n A 1 152 ALA 152 152 152 ALA ALA A . n A 1 153 ASP 153 153 153 ASP ASP A . n A 1 154 GLN 154 154 154 GLN GLN A . n A 1 155 GLY 155 155 155 GLY GLY A . n A 1 156 THR 156 156 156 THR THR A . n A 1 157 SER 157 157 157 SER SER A . n A 1 158 ALA 158 158 158 ALA ALA A . n A 1 159 THR 159 159 159 THR THR A . n A 1 160 VAL 160 160 160 VAL VAL A . n A 1 161 GLN 161 161 161 GLN GLN A . n A 1 162 MET 162 162 162 MET MET A . n A 1 163 LEU 163 163 163 LEU LEU A . n A 1 164 LEU 164 164 164 LEU LEU A . n A 1 165 ASN 165 165 165 ASN ASN A . n A 1 166 ASP 166 166 166 ASP ASP A . n A 1 167 THR 167 167 167 THR THR A . n A 1 168 CYS 168 168 168 CYS CYS A . n A 1 169 PRO 169 169 169 PRO PRO A . n A 1 170 LEU 170 170 170 LEU LEU A . n A 1 171 PHE 171 171 171 PHE PHE A . n A 1 172 VAL 172 172 172 VAL VAL A . n A 1 173 ARG 173 173 173 ARG ARG A . n A 1 174 GLY 174 174 174 GLY GLY A . n A 1 175 LEU 175 175 175 LEU LEU A . n A 1 176 LEU 176 176 176 LEU LEU A . n A 1 177 GLU 177 177 177 GLU GLU A . n A 1 178 ALA 178 178 178 ALA ALA A . n A 1 179 GLY 179 179 179 GLY GLY A . n A 1 180 LYS 180 180 180 LYS LYS A . n A 1 181 SER 181 181 181 SER SER A . n A 1 182 ASP 182 182 182 ASP ASP A . n A 1 183 LEU 183 183 183 LEU LEU A . n A 1 184 GLU 184 184 184 GLU GLU A . n A 1 185 LYS 185 185 185 LYS LYS A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 GLU 187 187 187 GLU GLU A . n A 1 188 LYS 188 188 188 LYS LYS A . n A 1 189 PRO 189 189 189 PRO PRO A . n A 1 190 VAL 190 190 190 VAL VAL A . n A 1 191 ALA 191 191 191 ALA ALA A . n A 1 192 TRP 192 192 192 TRP TRP A . n A 1 193 LEU 193 193 193 LEU LEU A . n A 1 194 SER 194 194 194 SER SER A . n A 1 195 SER 195 195 195 SER SER A . n A 1 196 VAL 196 196 196 VAL VAL A . n A 1 197 PRO 197 197 197 PRO PRO A . n A 1 198 SER 198 198 ? ? ? A . n A 1 199 SER 199 199 ? ? ? A . n A 1 200 ALA 200 200 ? ? ? A . n A 1 201 HIS 201 201 ? ? ? A . n A 1 202 GLY 202 202 ? ? ? A . n A 1 203 HIS 203 203 ? ? ? A . n A 1 204 ARG 204 204 204 ARG ARG A . n A 1 205 GLN 205 205 205 GLN GLN A . n A 1 206 LEU 206 206 206 LEU LEU A . n A 1 207 VAL 207 207 207 VAL VAL A . n A 1 208 CYS 208 208 208 CYS CYS A . n A 1 209 HIS 209 209 209 HIS HIS A . n A 1 210 VAL 210 210 210 VAL VAL A . n A 1 211 SER 211 211 211 SER SER A . n A 1 212 GLY 212 212 212 GLY GLY A . n A 1 213 PHE 213 213 213 PHE PHE A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 PRO 215 215 215 PRO PRO A . n A 1 216 LYS 216 216 216 LYS LYS A . n A 1 217 PRO 217 217 217 PRO PRO A . n A 1 218 VAL 218 218 218 VAL VAL A . n A 1 219 TRP 219 219 219 TRP TRP A . n A 1 220 VAL 220 220 220 VAL VAL A . n A 1 221 MET 221 221 221 MET MET A . n A 1 222 TRP 222 222 222 TRP TRP A . n A 1 223 MET 223 223 223 MET MET A . n A 1 224 ARG 224 224 224 ARG ARG A . n A 1 225 GLY 225 225 225 GLY GLY A . n A 1 226 ASP 226 226 226 ASP ASP A . n A 1 227 GLN 227 227 227 GLN GLN A . n A 1 228 GLU 228 228 228 GLU GLU A . n A 1 229 GLN 229 229 229 GLN GLN A . n A 1 230 GLN 230 230 230 GLN GLN A . n A 1 231 GLY 231 231 231 GLY GLY A . n A 1 232 THR 232 232 232 THR THR A . n A 1 233 HIS 233 233 233 HIS HIS A . n A 1 234 ARG 234 234 234 ARG ARG A . n A 1 235 GLY 235 235 235 GLY GLY A . n A 1 236 ASP 236 236 236 ASP ASP A . n A 1 237 PHE 237 237 237 PHE PHE A . n A 1 238 LEU 238 238 238 LEU LEU A . n A 1 239 PRO 239 239 239 PRO PRO A . n A 1 240 ASN 240 240 240 ASN ASN A . n A 1 241 ALA 241 241 241 ALA ALA A . n A 1 242 ASP 242 242 242 ASP ASP A . n A 1 243 GLU 243 243 243 GLU GLU A . n A 1 244 THR 244 244 244 THR THR A . n A 1 245 TRP 245 245 245 TRP TRP A . n A 1 246 TYR 246 246 246 TYR TYR A . n A 1 247 LEU 247 247 247 LEU LEU A . n A 1 248 GLN 248 248 248 GLN GLN A . n A 1 249 ALA 249 249 249 ALA ALA A . n A 1 250 THR 250 250 250 THR THR A . n A 1 251 LEU 251 251 251 LEU LEU A . n A 1 252 ASP 252 252 252 ASP ASP A . n A 1 253 VAL 253 253 253 VAL VAL A . n A 1 254 GLU 254 254 254 GLU GLU A . n A 1 255 ALA 255 255 255 ALA ALA A . n A 1 256 GLY 256 256 256 GLY GLY A . n A 1 257 GLU 257 257 257 GLU GLU A . n A 1 258 GLU 258 258 258 GLU GLU A . n A 1 259 ALA 259 259 259 ALA ALA A . n A 1 260 GLY 260 260 260 GLY GLY A . n A 1 261 LEU 261 261 261 LEU LEU A . n A 1 262 ALA 262 262 262 ALA ALA A . n A 1 263 CYS 263 263 263 CYS CYS A . n A 1 264 ARG 264 264 264 ARG ARG A . n A 1 265 VAL 265 265 265 VAL VAL A . n A 1 266 LYS 266 266 266 LYS LYS A . n A 1 267 HIS 267 267 267 HIS HIS A . n A 1 268 SER 268 268 268 SER SER A . n A 1 269 SER 269 269 269 SER SER A . n A 1 270 LEU 270 270 270 LEU LEU A . n A 1 271 GLY 271 271 271 GLY GLY A . n A 1 272 GLY 272 272 272 GLY GLY A . n A 1 273 GLN 273 273 273 GLN GLN A . n A 1 274 ASP 274 274 274 ASP ASP A . n A 1 275 ILE 275 275 275 ILE ILE A . n A 1 276 ILE 276 276 276 ILE ILE A . n A 1 277 LEU 277 277 277 LEU LEU A . n A 1 278 TYR 278 278 278 TYR TYR A . n A 1 279 TRP 279 279 279 TRP TRP A . n A 1 280 HIS 280 280 ? ? ? A . n A 1 281 HIS 281 281 ? ? ? A . n A 1 282 HIS 282 282 ? ? ? A . n A 1 283 HIS 283 283 ? ? ? A . n A 1 284 HIS 284 284 ? ? ? A . n A 1 285 HIS 285 285 ? ? ? A . n B 2 1 ILE 1 1 ? ? ? B . n B 2 2 GLN 2 2 2 GLN GLN B . n B 2 3 LYS 3 3 3 LYS LYS B . n B 2 4 THR 4 4 4 THR THR B . n B 2 5 PRO 5 5 5 PRO PRO B . n B 2 6 GLN 6 6 6 GLN GLN B . n B 2 7 ILE 7 7 7 ILE ILE B . n B 2 8 GLN 8 8 8 GLN GLN B . n B 2 9 VAL 9 9 9 VAL VAL B . n B 2 10 TYR 10 10 10 TYR TYR B . n B 2 11 SER 11 11 11 SER SER B . n B 2 12 ARG 12 12 12 ARG ARG B . n B 2 13 HIS 13 13 13 HIS HIS B . n B 2 14 PRO 14 14 14 PRO PRO B . n B 2 15 PRO 15 15 15 PRO PRO B . n B 2 16 GLU 16 16 16 GLU GLU B . n B 2 17 ASN 17 17 17 ASN ASN B . n B 2 18 GLY 18 18 18 GLY GLY B . n B 2 19 LYS 19 19 19 LYS LYS B . n B 2 20 PRO 20 20 20 PRO PRO B . n B 2 21 ASN 21 21 21 ASN ASN B . n B 2 22 ILE 22 22 22 ILE ILE B . n B 2 23 LEU 23 23 23 LEU LEU B . n B 2 24 ASN 24 24 24 ASN ASN B . n B 2 25 CYS 25 25 25 CYS CYS B . n B 2 26 TYR 26 26 26 TYR TYR B . n B 2 27 VAL 27 27 27 VAL VAL B . n B 2 28 THR 28 28 28 THR THR B . n B 2 29 GLN 29 29 29 GLN GLN B . n B 2 30 PHE 30 30 30 PHE PHE B . n B 2 31 HIS 31 31 31 HIS HIS B . n B 2 32 PRO 32 32 32 PRO PRO B . n B 2 33 PRO 33 33 33 PRO PRO B . n B 2 34 HIS 34 34 34 HIS HIS B . n B 2 35 ILE 35 35 35 ILE ILE B . n B 2 36 GLU 36 36 36 GLU GLU B . n B 2 37 ILE 37 37 37 ILE ILE B . n B 2 38 GLN 38 38 38 GLN GLN B . n B 2 39 MET 39 39 39 MET MET B . n B 2 40 LEU 40 40 40 LEU LEU B . n B 2 41 LYS 41 41 41 LYS LYS B . n B 2 42 ASN 42 42 42 ASN ASN B . n B 2 43 GLY 43 43 43 GLY GLY B . n B 2 44 LYS 44 44 44 LYS LYS B . n B 2 45 LYS 45 45 45 LYS LYS B . n B 2 46 ILE 46 46 46 ILE ILE B . n B 2 47 PRO 47 47 47 PRO PRO B . n B 2 48 LYS 48 48 48 LYS LYS B . n B 2 49 VAL 49 49 49 VAL VAL B . n B 2 50 GLU 50 50 50 GLU GLU B . n B 2 51 MET 51 51 51 MET MET B . n B 2 52 SER 52 52 52 SER SER B . n B 2 53 ASP 53 53 53 ASP ASP B . n B 2 54 MET 54 54 54 MET MET B . n B 2 55 SER 55 55 55 SER SER B . n B 2 56 PHE 56 56 56 PHE PHE B . n B 2 57 SER 57 57 57 SER SER B . n B 2 58 LYS 58 58 58 LYS LYS B . n B 2 59 ASP 59 59 59 ASP ASP B . n B 2 60 TRP 60 60 60 TRP TRP B . n B 2 61 SER 61 61 61 SER SER B . n B 2 62 PHE 62 62 62 PHE PHE B . n B 2 63 TYR 63 63 63 TYR TYR B . n B 2 64 ILE 64 64 64 ILE ILE B . n B 2 65 LEU 65 65 65 LEU LEU B . n B 2 66 ALA 66 66 66 ALA ALA B . n B 2 67 HIS 67 67 67 HIS HIS B . n B 2 68 THR 68 68 68 THR THR B . n B 2 69 GLU 69 69 69 GLU GLU B . n B 2 70 PHE 70 70 70 PHE PHE B . n B 2 71 THR 71 71 71 THR THR B . n B 2 72 PRO 72 72 72 PRO PRO B . n B 2 73 THR 73 73 73 THR THR B . n B 2 74 GLU 74 74 74 GLU GLU B . n B 2 75 THR 75 75 75 THR THR B . n B 2 76 ASP 76 76 76 ASP ASP B . n B 2 77 THR 77 77 77 THR THR B . n B 2 78 TYR 78 78 78 TYR TYR B . n B 2 79 ALA 79 79 79 ALA ALA B . n B 2 80 CYS 80 80 80 CYS CYS B . n B 2 81 ARG 81 81 81 ARG ARG B . n B 2 82 VAL 82 82 82 VAL VAL B . n B 2 83 LYS 83 83 83 LYS LYS B . n B 2 84 HIS 84 84 84 HIS HIS B . n B 2 85 ALA 85 85 85 ALA ALA B . n B 2 86 SER 86 86 86 SER SER B . n B 2 87 MET 87 87 87 MET MET B . n B 2 88 ALA 88 88 88 ALA ALA B . n B 2 89 GLU 89 89 89 GLU GLU B . n B 2 90 PRO 90 90 90 PRO PRO B . n B 2 91 LYS 91 91 91 LYS LYS B . n B 2 92 THR 92 92 92 THR THR B . n B 2 93 VAL 93 93 93 VAL VAL B . n B 2 94 TYR 94 94 94 TYR TYR B . n B 2 95 TRP 95 95 95 TRP TRP B . n B 2 96 ASP 96 96 96 ASP ASP B . n B 2 97 ARG 97 97 97 ARG ARG B . n B 2 98 ASP 98 98 98 ASP ASP B . n B 2 99 MET 99 99 99 MET MET B . n C 3 1 MET 1 -1 ? ? ? C . n C 3 2 LYS 2 0 ? ? ? C . n C 3 3 THR 3 1 1 THR THR C . n C 3 4 GLN 4 2 2 GLN GLN C . n C 3 5 VAL 5 3 3 VAL VAL C . n C 3 6 GLU 6 4 4 GLU GLU C . n C 3 7 GLN 7 5 5 GLN GLN C . n C 3 8 SER 8 6 6 SER SER C . n C 3 9 PRO 9 7 7 PRO PRO C . n C 3 10 GLN 10 8 8 GLN GLN C . n C 3 11 SER 11 9 9 SER SER C . n C 3 12 LEU 12 10 10 LEU LEU C . n C 3 13 VAL 13 11 11 VAL VAL C . n C 3 14 VAL 14 12 12 VAL VAL C . n C 3 15 ARG 15 13 13 ARG ARG C . n C 3 16 GLN 16 14 14 GLN GLN C . n C 3 17 GLY 17 15 15 GLY GLY C . n C 3 18 GLU 18 16 16 GLU GLU C . n C 3 19 ASN 19 17 17 ASN ASN C . n C 3 20 CYS 20 18 18 CYS CYS C . n C 3 21 VAL 21 19 19 VAL VAL C . n C 3 22 LEU 22 20 20 LEU LEU C . n C 3 23 GLN 23 21 21 GLN GLN C . n C 3 24 CYS 24 22 22 CYS CYS C . n C 3 25 ASN 25 23 23 ASN ASN C . n C 3 26 TYR 26 24 24 TYR TYR C . n C 3 27 SER 27 25 25 SER SER C . n C 3 28 VAL 28 26 26 VAL VAL C . n C 3 29 THR 29 27 27 THR THR C . n C 3 30 PRO 30 28 28 PRO PRO C . n C 3 31 ASP 31 29 29 ASP ASP C . n C 3 32 ASN 32 30 30 ASN ASN C . n C 3 33 HIS 33 31 31 HIS HIS C . n C 3 34 LEU 34 32 32 LEU LEU C . n C 3 35 ARG 35 33 33 ARG ARG C . n C 3 36 TRP 36 34 34 TRP TRP C . n C 3 37 PHE 37 35 35 PHE PHE C . n C 3 38 LYS 38 36 36 LYS LYS C . n C 3 39 GLN 39 37 37 GLN GLN C . n C 3 40 ASP 40 38 38 ASP ASP C . n C 3 41 THR 41 39 39 THR THR C . n C 3 42 GLY 42 40 40 GLY GLY C . n C 3 43 LYS 43 41 41 LYS LYS C . n C 3 44 GLY 44 42 42 GLY GLY C . n C 3 45 LEU 45 43 43 LEU LEU C . n C 3 46 VAL 46 44 44 VAL VAL C . n C 3 47 SER 47 45 45 SER SER C . n C 3 48 LEU 48 46 46 LEU LEU C . n C 3 49 THR 49 47 47 THR THR C . n C 3 50 VAL 50 48 48 VAL VAL C . n C 3 51 LEU 51 49 49 LEU LEU C . n C 3 52 VAL 52 50 50 VAL VAL C . n C 3 53 ASP 53 51 51 ASP ASP C . n C 3 54 GLN 54 52 52 GLN GLN C . n C 3 55 LYS 55 53 53 LYS LYS C . n C 3 56 ASP 56 54 54 ASP ASP C . n C 3 57 LYS 57 55 55 LYS LYS C . n C 3 58 THR 58 56 56 THR THR C . n C 3 59 SER 59 57 57 SER SER C . n C 3 60 ASN 60 58 58 ASN ASN C . n C 3 61 GLY 61 59 59 GLY GLY C . n C 3 62 ARG 62 60 60 ARG ARG C . n C 3 63 TYR 63 61 61 TYR TYR C . n C 3 64 SER 64 62 62 SER SER C . n C 3 65 ALA 65 63 63 ALA ALA C . n C 3 66 THR 66 64 64 THR THR C . n C 3 67 LEU 67 65 65 LEU LEU C . n C 3 68 ASP 68 66 66 ASP ASP C . n C 3 69 LYS 69 67 67 LYS LYS C . n C 3 70 ASP 70 68 68 ASP ASP C . n C 3 71 ALA 71 69 69 ALA ALA C . n C 3 72 LYS 72 70 70 LYS LYS C . n C 3 73 HIS 73 71 71 HIS HIS C . n C 3 74 SER 74 72 72 SER SER C . n C 3 75 THR 75 73 73 THR THR C . n C 3 76 LEU 76 74 74 LEU LEU C . n C 3 77 HIS 77 75 75 HIS HIS C . n C 3 78 ILE 78 76 76 ILE ILE C . n C 3 79 THR 79 77 77 THR THR C . n C 3 80 ALA 80 78 78 ALA ALA C . n C 3 81 THR 81 79 79 THR THR C . n C 3 82 LEU 82 80 80 LEU LEU C . n C 3 83 LEU 83 81 81 LEU LEU C . n C 3 84 ASP 84 82 82 ASP ASP C . n C 3 85 ASP 85 83 83 ASP ASP C . n C 3 86 THR 86 84 84 THR THR C . n C 3 87 ALA 87 85 85 ALA ALA C . n C 3 88 THR 88 86 86 THR THR C . n C 3 89 TYR 89 87 87 TYR TYR C . n C 3 90 ILE 90 88 88 ILE ILE C . n C 3 91 CYS 91 89 89 CYS CYS C . n C 3 92 VAL 92 90 90 VAL VAL C . n C 3 93 VAL 93 91 91 VAL VAL C . n C 3 94 GLY 94 92 92 GLY GLY C . n C 3 95 ASP 95 93 93 ASP ASP C . n C 3 96 ARG 96 94 94 ARG ARG C . n C 3 97 GLY 97 95 95 GLY GLY C . n C 3 98 SER 98 96 96 SER SER C . n C 3 99 ALA 99 97 97 ALA ALA C . n C 3 100 LEU 100 98 98 LEU LEU C . n C 3 101 GLY 101 99 99 GLY GLY C . n C 3 102 ARG 102 100 100 ARG ARG C . n C 3 103 LEU 103 101 101 LEU LEU C . n C 3 104 HIS 104 102 102 HIS HIS C . n C 3 105 PHE 105 103 103 PHE PHE C . n C 3 106 GLY 106 104 104 GLY GLY C . n C 3 107 ALA 107 105 105 ALA ALA C . n C 3 108 GLY 108 106 106 GLY GLY C . n C 3 109 THR 109 107 107 THR THR C . n C 3 110 GLN 110 108 108 GLN GLN C . n C 3 111 LEU 111 109 109 LEU LEU C . n C 3 112 ILE 112 110 110 ILE ILE C . n C 3 113 VAL 113 111 111 VAL VAL C . n C 3 114 ILE 114 112 112 ILE ILE C . n C 3 115 PRO 115 113 113 PRO PRO C . n C 3 116 ASP 116 114 114 ASP ASP C . n C 3 117 ILE 117 115 115 ILE ILE C . n C 3 118 GLN 118 116 116 GLN GLN C . n C 3 119 ASN 119 117 117 ASN ASN C . n C 3 120 PRO 120 118 118 PRO PRO C . n C 3 121 ASP 121 119 119 ASP ASP C . n C 3 122 PRO 122 120 120 PRO PRO C . n C 3 123 ALA 123 121 121 ALA ALA C . n C 3 124 VAL 124 122 122 VAL VAL C . n C 3 125 TYR 125 123 123 TYR TYR C . n C 3 126 GLN 126 124 124 GLN GLN C . n C 3 127 LEU 127 125 125 LEU LEU C . n C 3 128 ARG 128 126 126 ARG ARG C . n C 3 129 ASP 129 127 127 ASP ASP C . n C 3 130 SER 130 128 128 SER SER C . n C 3 131 LYS 131 129 129 LYS LYS C . n C 3 132 SER 132 130 130 SER SER C . n C 3 133 SER 133 131 131 SER SER C . n C 3 134 ASP 134 132 132 ASP ASP C . n C 3 135 LYS 135 133 133 LYS LYS C . n C 3 136 SER 136 134 134 SER SER C . n C 3 137 VAL 137 135 135 VAL VAL C . n C 3 138 CYS 138 136 136 CYS CYS C . n C 3 139 LEU 139 137 137 LEU LEU C . n C 3 140 PHE 140 138 138 PHE PHE C . n C 3 141 THR 141 139 139 THR THR C . n C 3 142 ASP 142 140 140 ASP ASP C . n C 3 143 PHE 143 141 141 PHE PHE C . n C 3 144 ASP 144 142 142 ASP ASP C . n C 3 145 SER 145 143 143 SER SER C . n C 3 146 GLN 146 144 144 GLN GLN C . n C 3 147 THR 147 145 145 THR THR C . n C 3 148 ASN 148 146 146 ASN ASN C . n C 3 149 VAL 149 147 147 VAL VAL C . n C 3 150 SER 150 148 148 SER SER C . n C 3 151 GLN 151 149 149 GLN GLN C . n C 3 152 SER 152 150 150 SER SER C . n C 3 153 LYS 153 151 151 LYS LYS C . n C 3 154 ASP 154 152 152 ASP ASP C . n C 3 155 SER 155 153 153 SER SER C . n C 3 156 ASP 156 154 154 ASP ASP C . n C 3 157 VAL 157 155 155 VAL VAL C . n C 3 158 TYR 158 156 156 TYR TYR C . n C 3 159 ILE 159 157 157 ILE ILE C . n C 3 160 THR 160 158 158 THR THR C . n C 3 161 ASP 161 159 159 ASP ASP C . n C 3 162 LYS 162 160 160 LYS LYS C . n C 3 163 CYS 163 161 161 CYS CYS C . n C 3 164 VAL 164 162 162 VAL VAL C . n C 3 165 LEU 165 163 163 LEU LEU C . n C 3 166 ASP 166 164 164 ASP ASP C . n C 3 167 MET 167 165 165 MET MET C . n C 3 168 ARG 168 166 166 ARG ARG C . n C 3 169 SER 169 167 167 SER SER C . n C 3 170 MET 170 168 168 MET MET C . n C 3 171 ASP 171 169 169 ASP ASP C . n C 3 172 PHE 172 170 170 PHE PHE C . n C 3 173 LYS 173 171 171 LYS LYS C . n C 3 174 SER 174 172 172 SER SER C . n C 3 175 ASN 175 173 173 ASN ASN C . n C 3 176 SER 176 174 174 SER SER C . n C 3 177 ALA 177 175 175 ALA ALA C . n C 3 178 VAL 178 176 176 VAL VAL C . n C 3 179 ALA 179 177 177 ALA ALA C . n C 3 180 TRP 180 178 178 TRP TRP C . n C 3 181 SER 181 179 179 SER SER C . n C 3 182 ASN 182 180 180 ASN ASN C . n C 3 183 LYS 183 181 181 LYS LYS C . n C 3 184 SER 184 182 ? ? ? C . n C 3 185 ASP 185 183 183 ASP ASP C . n C 3 186 PHE 186 184 184 PHE PHE C . n C 3 187 ALA 187 185 185 ALA ALA C . n C 3 188 CYS 188 186 186 CYS CYS C . n C 3 189 ALA 189 187 187 ALA ALA C . n C 3 190 ASN 190 188 188 ASN ASN C . n C 3 191 ALA 191 189 189 ALA ALA C . n C 3 192 PHE 192 190 190 PHE PHE C . n C 3 193 ASN 193 191 191 ASN ASN C . n C 3 194 ASN 194 192 192 ASN ASN C . n C 3 195 SER 195 193 193 SER SER C . n C 3 196 ILE 196 194 194 ILE ILE C . n C 3 197 ILE 197 195 195 ILE ILE C . n C 3 198 PRO 198 196 196 PRO PRO C . n C 3 199 GLU 199 197 197 GLU GLU C . n C 3 200 ASP 200 198 198 ASP ASP C . n C 3 201 THR 201 199 199 THR THR C . n C 3 202 PHE 202 200 200 PHE PHE C . n C 3 203 PHE 203 201 201 PHE PHE C . n C 3 204 PRO 204 202 202 PRO PRO C . n C 3 205 SER 205 203 203 SER SER C . n C 3 206 PRO 206 204 ? ? ? C . n C 3 207 GLU 207 205 ? ? ? C . n C 3 208 SER 208 206 ? ? ? C . n C 3 209 SER 209 207 ? ? ? C . n D 4 1 MET 1 0 ? ? ? D . n D 4 2 GLU 2 1 ? ? ? D . n D 4 3 ALA 3 2 2 ALA ALA D . n D 4 4 ALA 4 3 3 ALA ALA D . n D 4 5 VAL 5 4 4 VAL VAL D . n D 4 6 THR 6 5 5 THR THR D . n D 4 7 GLN 7 6 6 GLN GLN D . n D 4 8 SER 8 7 7 SER SER D . n D 4 9 PRO 9 8 8 PRO PRO D . n D 4 10 ARG 10 9 9 ARG ARG D . n D 4 11 ASN 11 10 10 ASN ASN D . n D 4 12 LYS 12 11 11 LYS LYS D . n D 4 13 VAL 13 12 12 VAL VAL D . n D 4 14 ALA 14 13 13 ALA ALA D . n D 4 15 VAL 15 14 14 VAL VAL D . n D 4 16 THR 16 15 15 THR THR D . n D 4 17 GLY 17 16 16 GLY GLY D . n D 4 18 GLY 18 17 17 GLY GLY D . n D 4 19 LYS 19 18 18 LYS LYS D . n D 4 20 VAL 20 19 19 VAL VAL D . n D 4 21 THR 21 20 20 THR THR D . n D 4 22 LEU 22 21 21 LEU LEU D . n D 4 23 SER 23 22 22 SER SER D . n D 4 24 CYS 24 23 23 CYS CYS D . n D 4 25 ASN 25 24 24 ASN ASN D . n D 4 26 GLN 26 25 25 GLN GLN D . n D 4 27 THR 27 26 26 THR THR D . n D 4 28 ASN 28 27 27 ASN ASN D . n D 4 29 ASN 29 28 28 ASN ASN D . n D 4 30 HIS 30 29 29 HIS HIS D . n D 4 31 ASN 31 30 30 ASN ASN D . n D 4 32 ASN 32 31 31 ASN ASN D . n D 4 33 MET 33 32 32 MET MET D . n D 4 34 TYR 34 33 33 TYR TYR D . n D 4 35 TRP 35 34 34 TRP TRP D . n D 4 36 TYR 36 35 35 TYR TYR D . n D 4 37 ARG 37 36 36 ARG ARG D . n D 4 38 GLN 38 37 37 GLN GLN D . n D 4 39 ASP 39 38 38 ASP ASP D . n D 4 40 THR 40 39 39 THR THR D . n D 4 41 GLY 41 40 40 GLY GLY D . n D 4 42 HIS 42 41 41 HIS HIS D . n D 4 43 GLY 43 42 42 GLY GLY D . n D 4 44 LEU 44 43 43 LEU LEU D . n D 4 45 ARG 45 44 44 ARG ARG D . n D 4 46 LEU 46 45 45 LEU LEU D . n D 4 47 ILE 47 46 46 ILE ILE D . n D 4 48 HIS 48 47 47 HIS HIS D . n D 4 49 TYR 49 48 48 TYR TYR D . n D 4 50 SER 50 49 49 SER SER D . n D 4 51 TYR 51 50 50 TYR TYR D . n D 4 52 GLY 52 51 51 GLY GLY D . n D 4 53 ALA 53 52 52 ALA ALA D . n D 4 54 GLY 54 53 53 GLY GLY D . n D 4 55 SER 55 54 54 SER SER D . n D 4 56 THR 56 55 55 THR THR D . n D 4 57 GLU 57 56 56 GLU GLU D . n D 4 58 LYS 58 57 57 LYS LYS D . n D 4 59 GLY 59 58 58 GLY GLY D . n D 4 60 ASP 60 59 59 ASP ASP D . n D 4 61 ILE 61 60 60 ILE ILE D . n D 4 62 PRO 62 61 61 PRO PRO D . n D 4 63 ASP 63 62 62 ASP ASP D . n D 4 64 GLY 64 63 63 GLY GLY D . n D 4 65 TYR 65 64 64 TYR TYR D . n D 4 66 LYS 66 65 65 LYS LYS D . n D 4 67 ALA 67 66 66 ALA ALA D . n D 4 68 SER 68 67 67 SER SER D . n D 4 69 ARG 69 68 68 ARG ARG D . n D 4 70 PRO 70 69 69 PRO PRO D . n D 4 71 SER 71 70 70 SER SER D . n D 4 72 GLN 72 71 71 GLN GLN D . n D 4 73 GLU 73 72 72 GLU GLU D . n D 4 74 ASN 74 73 73 ASN ASN D . n D 4 75 PHE 75 74 74 PHE PHE D . n D 4 76 SER 76 75 75 SER SER D . n D 4 77 LEU 77 76 76 LEU LEU D . n D 4 78 ILE 78 77 77 ILE ILE D . n D 4 79 LEU 79 78 78 LEU LEU D . n D 4 80 GLU 80 79 79 GLU GLU D . n D 4 81 LEU 81 80 80 LEU LEU D . n D 4 82 ALA 82 81 81 ALA ALA D . n D 4 83 THR 83 82 82 THR THR D . n D 4 84 PRO 84 83 83 PRO PRO D . n D 4 85 SER 85 84 84 SER SER D . n D 4 86 GLN 86 85 85 GLN GLN D . n D 4 87 THR 87 86 86 THR THR D . n D 4 88 SER 88 87 87 SER SER D . n D 4 89 VAL 89 88 88 VAL VAL D . n D 4 90 TYR 90 89 89 TYR TYR D . n D 4 91 PHE 91 90 90 PHE PHE D . n D 4 92 CYS 92 91 91 CYS CYS D . n D 4 93 ALA 93 92 92 ALA ALA D . n D 4 94 SER 94 93 93 SER SER D . n D 4 95 GLY 95 94 94 GLY GLY D . n D 4 96 ASP 96 95 95 ASP ASP D . n D 4 97 GLU 97 96 96 GLU GLU D . n D 4 98 GLY 98 97 97 GLY GLY D . n D 4 99 TYR 99 98 98 TYR TYR D . n D 4 100 THR 100 99 99 THR THR D . n D 4 101 GLN 101 100 100 GLN GLN D . n D 4 102 TYR 102 101 101 TYR TYR D . n D 4 103 PHE 103 102 102 PHE PHE D . n D 4 104 GLY 104 103 103 GLY GLY D . n D 4 105 PRO 105 104 104 PRO PRO D . n D 4 106 GLY 106 105 105 GLY GLY D . n D 4 107 THR 107 106 106 THR THR D . n D 4 108 ARG 108 107 107 ARG ARG D . n D 4 109 LEU 109 108 108 LEU LEU D . n D 4 110 LEU 110 109 109 LEU LEU D . n D 4 111 VAL 111 110 110 VAL VAL D . n D 4 112 LEU 112 111 111 LEU LEU D . n D 4 113 GLU 113 112 112 GLU GLU D . n D 4 114 ASP 114 113 113 ASP ASP D . n D 4 115 LEU 115 114 114 LEU LEU D . n D 4 116 ARG 116 115 115 ARG ARG D . n D 4 117 ASN 117 116 116 ASN ASN D . n D 4 118 VAL 118 117 117 VAL VAL D . n D 4 119 THR 119 118 118 THR THR D . n D 4 120 PRO 120 119 119 PRO PRO D . n D 4 121 PRO 121 120 120 PRO PRO D . n D 4 122 LYS 122 121 121 LYS LYS D . n D 4 123 VAL 123 122 122 VAL VAL D . n D 4 124 SER 124 123 123 SER SER D . n D 4 125 LEU 125 124 124 LEU LEU D . n D 4 126 PHE 126 125 125 PHE PHE D . n D 4 127 GLU 127 126 126 GLU GLU D . n D 4 128 PRO 128 127 127 PRO PRO D . n D 4 129 SER 129 128 128 SER SER D . n D 4 130 LYS 130 129 129 LYS LYS D . n D 4 131 ALA 131 130 130 ALA ALA D . n D 4 132 GLU 132 131 131 GLU GLU D . n D 4 133 ILE 133 132 132 ILE ILE D . n D 4 134 SER 134 133 133 SER SER D . n D 4 135 HIS 135 134 134 HIS HIS D . n D 4 136 THR 136 135 135 THR THR D . n D 4 137 GLN 137 136 136 GLN GLN D . n D 4 138 LYS 138 137 137 LYS LYS D . n D 4 139 ALA 139 138 138 ALA ALA D . n D 4 140 THR 140 139 139 THR THR D . n D 4 141 LEU 141 140 140 LEU LEU D . n D 4 142 VAL 142 141 141 VAL VAL D . n D 4 143 CYS 143 142 142 CYS CYS D . n D 4 144 LEU 144 143 143 LEU LEU D . n D 4 145 ALA 145 144 144 ALA ALA D . n D 4 146 THR 146 145 145 THR THR D . n D 4 147 GLY 147 146 146 GLY GLY D . n D 4 148 PHE 148 147 147 PHE PHE D . n D 4 149 TYR 149 148 148 TYR TYR D . n D 4 150 PRO 150 149 149 PRO PRO D . n D 4 151 ASP 151 150 150 ASP ASP D . n D 4 152 HIS 152 151 151 HIS HIS D . n D 4 153 VAL 153 152 152 VAL VAL D . n D 4 154 GLU 154 153 153 GLU GLU D . n D 4 155 LEU 155 154 154 LEU LEU D . n D 4 156 SER 156 155 155 SER SER D . n D 4 157 TRP 157 156 156 TRP TRP D . n D 4 158 TRP 158 157 157 TRP TRP D . n D 4 159 VAL 159 158 158 VAL VAL D . n D 4 160 ASN 160 159 159 ASN ASN D . n D 4 161 GLY 161 160 160 GLY GLY D . n D 4 162 LYS 162 161 161 LYS LYS D . n D 4 163 GLU 163 162 162 GLU GLU D . n D 4 164 VAL 164 163 163 VAL VAL D . n D 4 165 HIS 165 164 164 HIS HIS D . n D 4 166 SER 166 165 165 SER SER D . n D 4 167 GLY 167 166 166 GLY GLY D . n D 4 168 VAL 168 167 167 VAL VAL D . n D 4 169 CYS 169 168 168 CYS CYS D . n D 4 170 THR 170 169 169 THR THR D . n D 4 171 ASP 171 170 170 ASP ASP D . n D 4 172 PRO 172 171 171 PRO PRO D . n D 4 173 GLN 173 172 172 GLN GLN D . n D 4 174 PRO 174 173 173 PRO PRO D . n D 4 175 LEU 175 174 174 LEU LEU D . n D 4 176 LYS 176 175 175 LYS LYS D . n D 4 177 GLU 177 176 176 GLU GLU D . n D 4 178 GLN 178 177 177 GLN GLN D . n D 4 179 PRO 179 178 178 PRO PRO D . n D 4 180 ALA 180 179 179 ALA ALA D . n D 4 181 LEU 181 180 180 LEU LEU D . n D 4 182 ASN 182 181 181 ASN ASN D . n D 4 183 ASP 183 182 182 ASP ASP D . n D 4 184 SER 184 183 183 SER SER D . n D 4 185 ARG 185 184 184 ARG ARG D . n D 4 186 TYR 186 185 185 TYR TYR D . n D 4 187 SER 187 186 186 SER SER D . n D 4 188 LEU 188 187 187 LEU LEU D . n D 4 189 SER 189 188 188 SER SER D . n D 4 190 SER 190 189 189 SER SER D . n D 4 191 ARG 191 190 190 ARG ARG D . n D 4 192 LEU 192 191 191 LEU LEU D . n D 4 193 ARG 193 192 192 ARG ARG D . n D 4 194 VAL 194 193 193 VAL VAL D . n D 4 195 SER 195 194 194 SER SER D . n D 4 196 ALA 196 195 195 ALA ALA D . n D 4 197 THR 197 196 196 THR THR D . n D 4 198 PHE 198 197 197 PHE PHE D . n D 4 199 TRP 199 198 198 TRP TRP D . n D 4 200 GLN 200 199 199 GLN GLN D . n D 4 201 ASN 201 200 200 ASN ASN D . n D 4 202 PRO 202 201 201 PRO PRO D . n D 4 203 ARG 203 202 202 ARG ARG D . n D 4 204 ASN 204 203 203 ASN ASN D . n D 4 205 HIS 205 204 204 HIS HIS D . n D 4 206 PHE 206 205 205 PHE PHE D . n D 4 207 ARG 207 206 206 ARG ARG D . n D 4 208 CYS 208 207 207 CYS CYS D . n D 4 209 GLN 209 208 208 GLN GLN D . n D 4 210 VAL 210 209 209 VAL VAL D . n D 4 211 GLN 211 210 210 GLN GLN D . n D 4 212 PHE 212 211 211 PHE PHE D . n D 4 213 TYR 213 212 212 TYR TYR D . n D 4 214 GLY 214 213 213 GLY GLY D . n D 4 215 LEU 215 214 214 LEU LEU D . n D 4 216 SER 216 215 215 SER SER D . n D 4 217 GLU 217 216 216 GLU GLU D . n D 4 218 ASN 218 217 217 ASN ASN D . n D 4 219 ASP 219 218 218 ASP ASP D . n D 4 220 GLU 220 219 219 GLU GLU D . n D 4 221 TRP 221 220 220 TRP TRP D . n D 4 222 THR 222 221 221 THR THR D . n D 4 223 GLN 223 222 222 GLN GLN D . n D 4 224 ASP 224 223 223 ASP ASP D . n D 4 225 ARG 225 224 224 ARG ARG D . n D 4 226 ALA 226 225 225 ALA ALA D . n D 4 227 LYS 227 226 226 LYS LYS D . n D 4 228 PRO 228 227 227 PRO PRO D . n D 4 229 VAL 229 228 228 VAL VAL D . n D 4 230 THR 230 229 229 THR THR D . n D 4 231 GLN 231 230 230 GLN GLN D . n D 4 232 ILE 232 231 231 ILE ILE D . n D 4 233 VAL 233 232 232 VAL VAL D . n D 4 234 SER 234 233 233 SER SER D . n D 4 235 ALA 235 234 234 ALA ALA D . n D 4 236 GLU 236 235 235 GLU GLU D . n D 4 237 ALA 237 236 236 ALA ALA D . n D 4 238 TRP 238 237 237 TRP TRP D . n D 4 239 GLY 239 238 238 GLY GLY D . n D 4 240 ARG 240 239 239 ARG ARG D . n D 4 241 ALA 241 240 240 ALA ALA D . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code E 5 NAG 1 301 1 NAG NAG A . F 5 NAG 1 302 1 NAG NAG A . G 5 NAG 2 303 1 NAG NAG A . H 5 NAG 1 304 1 NAG NAG A . I 5 NAG 2 305 1 NAG NAG A . J 6 FUL 3 306 1 FUL FUL A . K 7 1LA 1 307 1 1LA 1LA A . L 8 HOH 1 401 6 HOH HOH A . L 8 HOH 2 402 8 HOH HOH A . L 8 HOH 3 403 9 HOH HOH A . L 8 HOH 4 404 14 HOH HOH A . L 8 HOH 5 405 22 HOH HOH A . L 8 HOH 6 406 23 HOH HOH A . L 8 HOH 7 407 24 HOH HOH A . L 8 HOH 8 408 25 HOH HOH A . L 8 HOH 9 409 5 HOH HOH A . L 8 HOH 10 410 17 HOH HOH A . L 8 HOH 11 411 23 HOH HOH A . L 8 HOH 12 412 33 HOH HOH A . L 8 HOH 13 413 35 HOH HOH A . L 8 HOH 14 414 44 HOH HOH A . L 8 HOH 15 415 48 HOH HOH A . L 8 HOH 16 416 50 HOH HOH A . L 8 HOH 17 417 64 HOH HOH A . L 8 HOH 18 418 72 HOH HOH A . L 8 HOH 19 419 96 HOH HOH A . L 8 HOH 20 420 102 HOH HOH A . L 8 HOH 21 421 103 HOH HOH A . L 8 HOH 22 422 106 HOH HOH A . L 8 HOH 23 423 116 HOH HOH A . L 8 HOH 24 424 130 HOH HOH A . L 8 HOH 25 425 160 HOH HOH A . L 8 HOH 26 426 207 HOH HOH A . L 8 HOH 27 427 243 HOH HOH A . L 8 HOH 28 428 268 HOH HOH A . L 8 HOH 29 429 288 HOH HOH A . L 8 HOH 30 430 299 HOH HOH A . L 8 HOH 31 431 304 HOH HOH A . L 8 HOH 32 432 330 HOH HOH A . L 8 HOH 33 433 44 HOH HOH A . L 8 HOH 34 434 46 HOH HOH A . L 8 HOH 35 435 48 HOH HOH A . L 8 HOH 36 436 175 HOH HOH A . L 8 HOH 37 437 188 HOH HOH A . L 8 HOH 38 438 37 HOH HOH A . L 8 HOH 39 439 79 HOH HOH A . L 8 HOH 40 440 241 HOH HOH A . L 8 HOH 41 441 139 HOH HOH A . M 8 HOH 1 101 5 HOH HOH B . M 8 HOH 2 102 10 HOH HOH B . M 8 HOH 3 103 24 HOH HOH B . M 8 HOH 4 104 32 HOH HOH B . M 8 HOH 5 105 57 HOH HOH B . M 8 HOH 6 106 88 HOH HOH B . M 8 HOH 7 107 111 HOH HOH B . M 8 HOH 8 108 241 HOH HOH B . M 8 HOH 9 109 254 HOH HOH B . M 8 HOH 10 110 1 HOH HOH B . M 8 HOH 11 111 9 HOH HOH B . M 8 HOH 12 112 227 HOH HOH B . M 8 HOH 13 113 11 HOH HOH B . M 8 HOH 14 114 75 HOH HOH B . N 8 HOH 1 401 3 HOH HOH C . N 8 HOH 2 402 1 HOH HOH C . N 8 HOH 3 403 2 HOH HOH C . N 8 HOH 4 404 4 HOH HOH C . N 8 HOH 5 405 7 HOH HOH C . N 8 HOH 6 406 11 HOH HOH C . N 8 HOH 7 407 12 HOH HOH C . N 8 HOH 8 408 13 HOH HOH C . N 8 HOH 9 409 18 HOH HOH C . N 8 HOH 10 410 2 HOH HOH C . N 8 HOH 11 411 36 HOH HOH C . N 8 HOH 12 412 47 HOH HOH C . N 8 HOH 13 413 56 HOH HOH C . N 8 HOH 14 414 61 HOH HOH C . N 8 HOH 15 415 65 HOH HOH C . N 8 HOH 16 416 69 HOH HOH C . N 8 HOH 17 417 82 HOH HOH C . N 8 HOH 18 418 136 HOH HOH C . N 8 HOH 19 419 253 HOH HOH C . N 8 HOH 20 420 325 HOH HOH C . N 8 HOH 21 421 19 HOH HOH C . N 8 HOH 22 422 30 HOH HOH C . N 8 HOH 23 423 62 HOH HOH C . N 8 HOH 24 424 91 HOH HOH C . N 8 HOH 25 425 100 HOH HOH C . O 8 HOH 1 301 15 HOH HOH D . O 8 HOH 2 302 16 HOH HOH D . O 8 HOH 3 303 17 HOH HOH D . O 8 HOH 4 304 19 HOH HOH D . O 8 HOH 5 305 20 HOH HOH D . O 8 HOH 6 306 21 HOH HOH D . O 8 HOH 7 307 3 HOH HOH D . O 8 HOH 8 308 6 HOH HOH D . O 8 HOH 9 309 19 HOH HOH D . O 8 HOH 10 310 27 HOH HOH D . O 8 HOH 11 311 38 HOH HOH D . O 8 HOH 12 312 43 HOH HOH D . O 8 HOH 13 313 58 HOH HOH D . O 8 HOH 14 314 63 HOH HOH D . O 8 HOH 15 315 127 HOH HOH D . O 8 HOH 16 316 145 HOH HOH D . O 8 HOH 17 317 161 HOH HOH D . O 8 HOH 18 318 162 HOH HOH D . O 8 HOH 19 319 218 HOH HOH D . O 8 HOH 20 320 222 HOH HOH D . O 8 HOH 21 321 233 HOH HOH D . O 8 HOH 22 322 326 HOH HOH D . O 8 HOH 23 323 38 HOH HOH D . O 8 HOH 24 324 47 HOH HOH D . O 8 HOH 25 325 50 HOH HOH D . O 8 HOH 26 326 133 HOH HOH D . O 8 HOH 27 327 167 HOH HOH D . O 8 HOH 28 328 208 HOH HOH D . O 8 HOH 29 329 12 HOH HOH D . O 8 HOH 30 330 52 HOH HOH D . O 8 HOH 31 331 114 HOH HOH D . O 8 HOH 32 332 143 HOH HOH D . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 165 A ASN 165 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 42 A ASN 42 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 20 A ASN 20 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details tetrameric _pdbx_struct_assembly.oligomeric_count 4 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2013-09-04 2 'Structure model' 1 1 2014-02-05 3 'Structure model' 1 2 2017-11-15 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 3 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # _pdbx_audit_revision_item.ordinal 1 _pdbx_audit_revision_item.revision_ordinal 3 _pdbx_audit_revision_item.data_content_type 'Structure model' _pdbx_audit_revision_item.item '_software.name' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal Blu-Ice 'data collection' Ice ? 1 MOLREP phasing . ? 2 REFMAC refinement 5.0 ? 3 iMOSFLM 'data reduction' . ? 4 SCALA 'data scaling' . ? 5 # _pdbx_validate_rmsd_bond.id 1 _pdbx_validate_rmsd_bond.PDB_model_num 1 _pdbx_validate_rmsd_bond.auth_atom_id_1 CG _pdbx_validate_rmsd_bond.auth_asym_id_1 C _pdbx_validate_rmsd_bond.auth_comp_id_1 HIS _pdbx_validate_rmsd_bond.auth_seq_id_1 75 _pdbx_validate_rmsd_bond.PDB_ins_code_1 ? _pdbx_validate_rmsd_bond.label_alt_id_1 ? _pdbx_validate_rmsd_bond.auth_atom_id_2 CD2 _pdbx_validate_rmsd_bond.auth_asym_id_2 C _pdbx_validate_rmsd_bond.auth_comp_id_2 HIS _pdbx_validate_rmsd_bond.auth_seq_id_2 75 _pdbx_validate_rmsd_bond.PDB_ins_code_2 ? _pdbx_validate_rmsd_bond.label_alt_id_2 ? _pdbx_validate_rmsd_bond.bond_value 1.414 _pdbx_validate_rmsd_bond.bond_target_value 1.354 _pdbx_validate_rmsd_bond.bond_deviation 0.060 _pdbx_validate_rmsd_bond.bond_standard_deviation 0.009 _pdbx_validate_rmsd_bond.linker_flag N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 VAL A 125 ? ? -130.59 -33.67 2 1 ASP A 166 ? ? -121.18 -53.97 3 1 ASP A 226 ? ? -145.62 40.34 4 1 GLU A 228 ? ? -52.59 106.85 5 1 GLU A 243 ? ? 72.59 51.06 6 1 TRP B 60 ? ? 70.16 -1.83 7 1 ASP C 119 ? ? -164.64 48.16 8 1 SER C 179 ? ? 167.10 122.82 9 1 ILE D 46 ? ? -91.04 -75.15 10 1 ALA D 52 ? ? -35.07 130.62 11 1 SER D 87 ? ? 178.07 -175.69 12 1 ASP D 95 ? ? -98.88 -147.41 13 1 ASP D 150 ? ? -79.94 25.40 14 1 ASP D 170 ? ? -36.00 130.93 15 1 GLN D 177 ? ? -160.62 66.58 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A ARG 21 ? CG ? A ARG 21 CG 2 1 Y 1 A ARG 21 ? CD ? A ARG 21 CD 3 1 Y 1 A ARG 21 ? NE ? A ARG 21 NE 4 1 Y 1 A ARG 21 ? CZ ? A ARG 21 CZ 5 1 Y 1 A ARG 21 ? NH1 ? A ARG 21 NH1 6 1 Y 1 A ARG 21 ? NH2 ? A ARG 21 NH2 7 1 Y 1 A VAL 29 ? CG1 ? A VAL 29 CG1 8 1 Y 1 A VAL 29 ? CG2 ? A VAL 29 CG2 9 1 Y 1 A LYS 123 ? CD ? A LYS 123 CD 10 1 Y 1 A LYS 123 ? CE ? A LYS 123 CE 11 1 Y 1 A LYS 123 ? NZ ? A LYS 123 NZ 12 1 Y 1 A SER 181 ? OG ? A SER 181 OG 13 1 Y 1 A GLN 230 ? CG ? A GLN 230 CG 14 1 Y 1 A GLN 230 ? CD ? A GLN 230 CD 15 1 Y 1 A GLN 230 ? OE1 ? A GLN 230 OE1 16 1 Y 1 A GLN 230 ? NE2 ? A GLN 230 NE2 17 1 Y 1 A GLU 254 ? CG ? A GLU 254 CG 18 1 Y 1 A GLU 254 ? CD ? A GLU 254 CD 19 1 Y 1 A GLU 254 ? OE1 ? A GLU 254 OE1 20 1 Y 1 A GLU 254 ? OE2 ? A GLU 254 OE2 21 1 Y 1 A ALA 259 ? CB ? A ALA 259 CB 22 1 Y 1 B LYS 3 ? CB ? B LYS 3 CB 23 1 Y 1 B LYS 3 ? CG ? B LYS 3 CG 24 1 Y 1 B LYS 3 ? CD ? B LYS 3 CD 25 1 Y 1 B LYS 3 ? CE ? B LYS 3 CE 26 1 Y 1 B LYS 3 ? NZ ? B LYS 3 NZ 27 1 Y 1 B GLU 36 ? CG ? B GLU 36 CG 28 1 Y 1 B GLU 36 ? CD ? B GLU 36 CD 29 1 Y 1 B GLU 36 ? OE1 ? B GLU 36 OE1 30 1 Y 1 B GLU 36 ? OE2 ? B GLU 36 OE2 31 1 Y 1 B LYS 48 ? CG ? B LYS 48 CG 32 1 Y 1 B LYS 48 ? CD ? B LYS 48 CD 33 1 Y 1 B LYS 48 ? CE ? B LYS 48 CE 34 1 Y 1 B LYS 48 ? NZ ? B LYS 48 NZ 35 1 Y 1 B LYS 58 ? CG ? B LYS 58 CG 36 1 Y 1 B LYS 58 ? CD ? B LYS 58 CD 37 1 Y 1 B LYS 58 ? CE ? B LYS 58 CE 38 1 Y 1 B LYS 58 ? NZ ? B LYS 58 NZ 39 1 Y 1 B LYS 83 ? CG ? B LYS 83 CG 40 1 Y 1 B LYS 83 ? CD ? B LYS 83 CD 41 1 Y 1 B LYS 83 ? CE ? B LYS 83 CE 42 1 Y 1 B LYS 83 ? NZ ? B LYS 83 NZ 43 1 Y 1 C LYS 41 ? CG ? C LYS 43 CG 44 1 Y 1 C LYS 41 ? CD ? C LYS 43 CD 45 1 Y 1 C LYS 41 ? CE ? C LYS 43 CE 46 1 Y 1 C LYS 41 ? NZ ? C LYS 43 NZ 47 1 Y 1 C LYS 129 ? CG ? C LYS 131 CG 48 1 Y 1 C LYS 129 ? CD ? C LYS 131 CD 49 1 Y 1 C LYS 129 ? CE ? C LYS 131 CE 50 1 Y 1 C LYS 129 ? NZ ? C LYS 131 NZ 51 1 Y 1 C GLN 144 ? CG ? C GLN 146 CG 52 1 Y 1 C GLN 144 ? CD ? C GLN 146 CD 53 1 Y 1 C GLN 144 ? OE1 ? C GLN 146 OE1 54 1 Y 1 C GLN 144 ? NE2 ? C GLN 146 NE2 55 1 Y 1 C LYS 151 ? CG ? C LYS 153 CG 56 1 Y 1 C LYS 151 ? CD ? C LYS 153 CD 57 1 Y 1 C LYS 151 ? CE ? C LYS 153 CE 58 1 Y 1 C LYS 151 ? NZ ? C LYS 153 NZ 59 1 Y 1 C ARG 166 ? CG ? C ARG 168 CG 60 1 Y 1 C ARG 166 ? CD ? C ARG 168 CD 61 1 Y 1 C ARG 166 ? NE ? C ARG 168 NE 62 1 Y 1 C ARG 166 ? CZ ? C ARG 168 CZ 63 1 Y 1 C ARG 166 ? NH1 ? C ARG 168 NH1 64 1 Y 1 C ARG 166 ? NH2 ? C ARG 168 NH2 65 1 Y 1 C LYS 181 ? CG ? C LYS 183 CG 66 1 Y 1 C LYS 181 ? CD ? C LYS 183 CD 67 1 Y 1 C LYS 181 ? CE ? C LYS 183 CE 68 1 Y 1 C LYS 181 ? NZ ? C LYS 183 NZ 69 1 Y 1 D LYS 129 ? CG ? D LYS 130 CG 70 1 Y 1 D LYS 129 ? CD ? D LYS 130 CD 71 1 Y 1 D LYS 129 ? CE ? D LYS 130 CE 72 1 Y 1 D LYS 129 ? NZ ? D LYS 130 NZ 73 1 Y 1 D GLU 216 ? CG ? D GLU 217 CG 74 1 Y 1 D GLU 216 ? CD ? D GLU 217 CD 75 1 Y 1 D GLU 216 ? OE1 ? D GLU 217 OE1 76 1 Y 1 D GLU 216 ? OE2 ? D GLU 217 OE2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A SER 1 ? A SER 1 2 1 Y 1 A GLU 2 ? A GLU 2 3 1 Y 1 A ALA 3 ? A ALA 3 4 1 Y 1 A GLN 4 ? A GLN 4 5 1 Y 1 A GLN 5 ? A GLN 5 6 1 Y 1 A SER 198 ? A SER 198 7 1 Y 1 A SER 199 ? A SER 199 8 1 Y 1 A ALA 200 ? A ALA 200 9 1 Y 1 A HIS 201 ? A HIS 201 10 1 Y 1 A GLY 202 ? A GLY 202 11 1 Y 1 A HIS 203 ? A HIS 203 12 1 Y 1 A HIS 280 ? A HIS 280 13 1 Y 1 A HIS 281 ? A HIS 281 14 1 Y 1 A HIS 282 ? A HIS 282 15 1 Y 1 A HIS 283 ? A HIS 283 16 1 Y 1 A HIS 284 ? A HIS 284 17 1 Y 1 A HIS 285 ? A HIS 285 18 1 Y 1 B ILE 1 ? B ILE 1 19 1 Y 1 C MET -1 ? C MET 1 20 1 Y 1 C LYS 0 ? C LYS 2 21 1 Y 1 C SER 182 ? C SER 184 22 1 Y 1 C PRO 204 ? C PRO 206 23 1 Y 1 C GLU 205 ? C GLU 207 24 1 Y 1 C SER 206 ? C SER 208 25 1 Y 1 C SER 207 ? C SER 209 26 1 Y 1 D MET 0 ? D MET 1 27 1 Y 1 D GLU 1 ? D GLU 2 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 5 N-ACETYL-D-GLUCOSAMINE NAG 6 BETA-L-FUCOSE FUL 7 'N-[(2S,3S,4R)-3,4-dihydroxy-1-{[6-O-(pyridin-4-ylcarbamoyl)-alpha-D-galactopyranosyl]oxy}octadecan-2-yl]hexacosanamide' 1LA 8 water HOH #