data_4FQI # _entry.id 4FQI # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.289 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4FQI RCSB RCSB073228 WWPDB D_1000073228 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 4FNK . unspecified PDB 4FQH . unspecified PDB 4FQJ . unspecified PDB 4FQK . unspecified PDB 4FQL . unspecified PDB 4FQM . unspecified PDB 4FQV . unspecified PDB 4FQY . unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 4FQI _pdbx_database_status.recvd_initial_deposition_date 2012-06-25 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Dreyfus, C.' 1 'Wilson, I.A.' 2 # _citation.id primary _citation.title 'Highly conserved protective epitopes on influenza B viruses.' _citation.journal_abbrev Science _citation.journal_volume 337 _citation.page_first 1343 _citation.page_last 1348 _citation.year 2012 _citation.journal_id_ASTM SCIEAS _citation.country US _citation.journal_id_ISSN 0036-8075 _citation.journal_id_CSD 0038 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 22878502 _citation.pdbx_database_id_DOI 10.1126/science.1222908 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Dreyfus, C.' 1 primary 'Laursen, N.S.' 2 primary 'Kwaks, T.' 3 primary 'Zuijdgeest, D.' 4 primary 'Khayat, R.' 5 primary 'Ekiert, D.C.' 6 primary 'Lee, J.H.' 7 primary 'Metlagel, Z.' 8 primary 'Bujny, M.V.' 9 primary 'Jongeneelen, M.' 10 primary 'van der Vlugt, R.' 11 primary 'Lamrani, M.' 12 primary 'Korse, H.J.' 13 primary 'Geelen, E.' 14 primary 'Sahin, O.' 15 primary 'Sieuwerts, M.' 16 primary 'Brakenhoff, J.P.' 17 primary 'Vogels, R.' 18 primary 'Li, O.T.' 19 primary 'Poon, L.L.' 20 primary 'Peiris, M.' 21 primary 'Koudstaal, W.' 22 primary 'Ward, A.B.' 23 primary 'Wilson, I.A.' 24 primary 'Goudsmit, J.' 25 primary 'Friesen, R.H.' 26 # _cell.entry_id 4FQI _cell.length_a 141.641 _cell.length_b 141.641 _cell.length_c 382.924 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 120.00 _cell.Z_PDB 18 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 4FQI _symmetry.space_group_name_H-M 'H 3 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 155 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Hemagglutinin HA1' 37948.020 1 ? ? 'UNP residues 17-346' ? 2 polymer man 'Hemagglutinin HA2' 20414.504 1 ? ? 'UNP residues 347-520' ? 3 polymer man 'antibody CR9114 heavy chain' 24423.191 1 ? ? Fab ? 4 polymer man 'antibody CR9114 light chain' 22840.172 1 ? ? 'Fab Lambda' ? 5 non-polymer syn 1,2-ETHANEDIOL 62.068 11 ? ? ? ? 6 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 5 ? ? ? ? 7 non-polymer syn GLYCEROL 92.094 1 ? ? ? ? 8 water nat water 18.015 1091 ? ? ? ? # loop_ _entity_name_com.entity_id _entity_name_com.name 1 'hemagglutinin receptor binding subunit HA1' 2 'hemagglutinin membrane fusion subunit HA2' # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;ADPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKKHNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFINVPEW SYIVEKANPVNDLCYPGDFNDYEELKHLLSRINHFEKIQIIPKSSWSSHEASLGVSSACPYQGKSSFFRNVVWLIKKNST YPTIKRSYNNTNQEDLLVLWGIHHPNDAAEQTKLYQNPTTYISVGTSTLNQRLVPRIATRSKVNGQSGRMEFFWTILKPN DAINFESNGNFIAPEYAYKIVKKGDSTIMKSELEYGNCNTKCQTPMGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATG LRNSPQRERRRKKR ; ;ADPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKKHNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFINVPEW SYIVEKANPVNDLCYPGDFNDYEELKHLLSRINHFEKIQIIPKSSWSSHEASLGVSSACPYQGKSSFFRNVVWLIKKNST YPTIKRSYNNTNQEDLLVLWGIHHPNDAAEQTKLYQNPTTYISVGTSTLNQRLVPRIATRSKVNGQSGRMEFFWTILKPN DAINFESNGNFIAPEYAYKIVKKGDSTIMKSELEYGNCNTKCQTPMGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATG LRNSPQRERRRKKR ; A ? 2 'polypeptide(L)' no no ;GLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENL NKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYDYP QYSEEARLKREEISSGR ; ;GLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENL NKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYDYP QYSEEARLKREEISSGR ; B ? 3 'polypeptide(L)' no no ;QVQLVQSGAEVKKPGSSVKVSCKSSGGTSNNYAISWVRQAPGQGLDWMGGISPIFGSTAYAQKFQGRVTISADIFSNTAY MELNSLTSEDTAVYFCARHGNYYYYSGMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTV SWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCHHHHHH ; ;QVQLVQSGAEVKKPGSSVKVSCKSSGGTSNNYAISWVRQAPGQGLDWMGGISPIFGSTAYAQKFQGRVTISADIFSNTAY MELNSLTSEDTAVYFCARHGNYYYYSGMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTV SWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCHHHHHH ; H ? 4 'polypeptide(L)' no no ;QSALTQPPAVSGTPGQRVTISCSGSDSNIGRRSVNWYQQFPGTAPKLLIYSNDQRPSVVPDRFSGSKSGTSASLAISGLQ SEDEAEYYCAAWDDSLKGAVFGGGTQLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVK AGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS ; ;QSALTQPPAVSGTPGQRVTISCSGSDSNIGRRSVNWYQQFPGTAPKLLIYSNDQRPSVVPDRFSGSKSGTSASLAISGLQ SEDEAEYYCAAWDDSLKGAVFGGGTQLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVK AGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS ; L ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ALA n 1 2 ASP n 1 3 PRO n 1 4 GLY n 1 5 ASP n 1 6 GLN n 1 7 ILE n 1 8 CYS n 1 9 ILE n 1 10 GLY n 1 11 TYR n 1 12 HIS n 1 13 ALA n 1 14 ASN n 1 15 ASN n 1 16 SER n 1 17 THR n 1 18 GLU n 1 19 GLN n 1 20 VAL n 1 21 ASP n 1 22 THR n 1 23 ILE n 1 24 MET n 1 25 GLU n 1 26 LYS n 1 27 ASN n 1 28 VAL n 1 29 THR n 1 30 VAL n 1 31 THR n 1 32 HIS n 1 33 ALA n 1 34 GLN n 1 35 ASP n 1 36 ILE n 1 37 LEU n 1 38 GLU n 1 39 LYS n 1 40 LYS n 1 41 HIS n 1 42 ASN n 1 43 GLY n 1 44 LYS n 1 45 LEU n 1 46 CYS n 1 47 ASP n 1 48 LEU n 1 49 ASP n 1 50 GLY n 1 51 VAL n 1 52 LYS n 1 53 PRO n 1 54 LEU n 1 55 ILE n 1 56 LEU n 1 57 ARG n 1 58 ASP n 1 59 CYS n 1 60 SER n 1 61 VAL n 1 62 ALA n 1 63 GLY n 1 64 TRP n 1 65 LEU n 1 66 LEU n 1 67 GLY n 1 68 ASN n 1 69 PRO n 1 70 MET n 1 71 CYS n 1 72 ASP n 1 73 GLU n 1 74 PHE n 1 75 ILE n 1 76 ASN n 1 77 VAL n 1 78 PRO n 1 79 GLU n 1 80 TRP n 1 81 SER n 1 82 TYR n 1 83 ILE n 1 84 VAL n 1 85 GLU n 1 86 LYS n 1 87 ALA n 1 88 ASN n 1 89 PRO n 1 90 VAL n 1 91 ASN n 1 92 ASP n 1 93 LEU n 1 94 CYS n 1 95 TYR n 1 96 PRO n 1 97 GLY n 1 98 ASP n 1 99 PHE n 1 100 ASN n 1 101 ASP n 1 102 TYR n 1 103 GLU n 1 104 GLU n 1 105 LEU n 1 106 LYS n 1 107 HIS n 1 108 LEU n 1 109 LEU n 1 110 SER n 1 111 ARG n 1 112 ILE n 1 113 ASN n 1 114 HIS n 1 115 PHE n 1 116 GLU n 1 117 LYS n 1 118 ILE n 1 119 GLN n 1 120 ILE n 1 121 ILE n 1 122 PRO n 1 123 LYS n 1 124 SER n 1 125 SER n 1 126 TRP n 1 127 SER n 1 128 SER n 1 129 HIS n 1 130 GLU n 1 131 ALA n 1 132 SER n 1 133 LEU n 1 134 GLY n 1 135 VAL n 1 136 SER n 1 137 SER n 1 138 ALA n 1 139 CYS n 1 140 PRO n 1 141 TYR n 1 142 GLN n 1 143 GLY n 1 144 LYS n 1 145 SER n 1 146 SER n 1 147 PHE n 1 148 PHE n 1 149 ARG n 1 150 ASN n 1 151 VAL n 1 152 VAL n 1 153 TRP n 1 154 LEU n 1 155 ILE n 1 156 LYS n 1 157 LYS n 1 158 ASN n 1 159 SER n 1 160 THR n 1 161 TYR n 1 162 PRO n 1 163 THR n 1 164 ILE n 1 165 LYS n 1 166 ARG n 1 167 SER n 1 168 TYR n 1 169 ASN n 1 170 ASN n 1 171 THR n 1 172 ASN n 1 173 GLN n 1 174 GLU n 1 175 ASP n 1 176 LEU n 1 177 LEU n 1 178 VAL n 1 179 LEU n 1 180 TRP n 1 181 GLY n 1 182 ILE n 1 183 HIS n 1 184 HIS n 1 185 PRO n 1 186 ASN n 1 187 ASP n 1 188 ALA n 1 189 ALA n 1 190 GLU n 1 191 GLN n 1 192 THR n 1 193 LYS n 1 194 LEU n 1 195 TYR n 1 196 GLN n 1 197 ASN n 1 198 PRO n 1 199 THR n 1 200 THR n 1 201 TYR n 1 202 ILE n 1 203 SER n 1 204 VAL n 1 205 GLY n 1 206 THR n 1 207 SER n 1 208 THR n 1 209 LEU n 1 210 ASN n 1 211 GLN n 1 212 ARG n 1 213 LEU n 1 214 VAL n 1 215 PRO n 1 216 ARG n 1 217 ILE n 1 218 ALA n 1 219 THR n 1 220 ARG n 1 221 SER n 1 222 LYS n 1 223 VAL n 1 224 ASN n 1 225 GLY n 1 226 GLN n 1 227 SER n 1 228 GLY n 1 229 ARG n 1 230 MET n 1 231 GLU n 1 232 PHE n 1 233 PHE n 1 234 TRP n 1 235 THR n 1 236 ILE n 1 237 LEU n 1 238 LYS n 1 239 PRO n 1 240 ASN n 1 241 ASP n 1 242 ALA n 1 243 ILE n 1 244 ASN n 1 245 PHE n 1 246 GLU n 1 247 SER n 1 248 ASN n 1 249 GLY n 1 250 ASN n 1 251 PHE n 1 252 ILE n 1 253 ALA n 1 254 PRO n 1 255 GLU n 1 256 TYR n 1 257 ALA n 1 258 TYR n 1 259 LYS n 1 260 ILE n 1 261 VAL n 1 262 LYS n 1 263 LYS n 1 264 GLY n 1 265 ASP n 1 266 SER n 1 267 THR n 1 268 ILE n 1 269 MET n 1 270 LYS n 1 271 SER n 1 272 GLU n 1 273 LEU n 1 274 GLU n 1 275 TYR n 1 276 GLY n 1 277 ASN n 1 278 CYS n 1 279 ASN n 1 280 THR n 1 281 LYS n 1 282 CYS n 1 283 GLN n 1 284 THR n 1 285 PRO n 1 286 MET n 1 287 GLY n 1 288 ALA n 1 289 ILE n 1 290 ASN n 1 291 SER n 1 292 SER n 1 293 MET n 1 294 PRO n 1 295 PHE n 1 296 HIS n 1 297 ASN n 1 298 ILE n 1 299 HIS n 1 300 PRO n 1 301 LEU n 1 302 THR n 1 303 ILE n 1 304 GLY n 1 305 GLU n 1 306 CYS n 1 307 PRO n 1 308 LYS n 1 309 TYR n 1 310 VAL n 1 311 LYS n 1 312 SER n 1 313 ASN n 1 314 ARG n 1 315 LEU n 1 316 VAL n 1 317 LEU n 1 318 ALA n 1 319 THR n 1 320 GLY n 1 321 LEU n 1 322 ARG n 1 323 ASN n 1 324 SER n 1 325 PRO n 1 326 GLN n 1 327 ARG n 1 328 GLU n 1 329 ARG n 1 330 ARG n 1 331 ARG n 1 332 LYS n 1 333 LYS n 1 334 ARG n 2 1 GLY n 2 2 LEU n 2 3 PHE n 2 4 GLY n 2 5 ALA n 2 6 ILE n 2 7 ALA n 2 8 GLY n 2 9 PHE n 2 10 ILE n 2 11 GLU n 2 12 GLY n 2 13 GLY n 2 14 TRP n 2 15 GLN n 2 16 GLY n 2 17 MET n 2 18 VAL n 2 19 ASP n 2 20 GLY n 2 21 TRP n 2 22 TYR n 2 23 GLY n 2 24 TYR n 2 25 HIS n 2 26 HIS n 2 27 SER n 2 28 ASN n 2 29 GLU n 2 30 GLN n 2 31 GLY n 2 32 SER n 2 33 GLY n 2 34 TYR n 2 35 ALA n 2 36 ALA n 2 37 ASP n 2 38 LYS n 2 39 GLU n 2 40 SER n 2 41 THR n 2 42 GLN n 2 43 LYS n 2 44 ALA n 2 45 ILE n 2 46 ASP n 2 47 GLY n 2 48 VAL n 2 49 THR n 2 50 ASN n 2 51 LYS n 2 52 VAL n 2 53 ASN n 2 54 SER n 2 55 ILE n 2 56 ILE n 2 57 ASP n 2 58 LYS n 2 59 MET n 2 60 ASN n 2 61 THR n 2 62 GLN n 2 63 PHE n 2 64 GLU n 2 65 ALA n 2 66 VAL n 2 67 GLY n 2 68 ARG n 2 69 GLU n 2 70 PHE n 2 71 ASN n 2 72 ASN n 2 73 LEU n 2 74 GLU n 2 75 ARG n 2 76 ARG n 2 77 ILE n 2 78 GLU n 2 79 ASN n 2 80 LEU n 2 81 ASN n 2 82 LYS n 2 83 LYS n 2 84 MET n 2 85 GLU n 2 86 ASP n 2 87 GLY n 2 88 PHE n 2 89 LEU n 2 90 ASP n 2 91 VAL n 2 92 TRP n 2 93 THR n 2 94 TYR n 2 95 ASN n 2 96 ALA n 2 97 GLU n 2 98 LEU n 2 99 LEU n 2 100 VAL n 2 101 LEU n 2 102 MET n 2 103 GLU n 2 104 ASN n 2 105 GLU n 2 106 ARG n 2 107 THR n 2 108 LEU n 2 109 ASP n 2 110 PHE n 2 111 HIS n 2 112 ASP n 2 113 SER n 2 114 ASN n 2 115 VAL n 2 116 LYS n 2 117 ASN n 2 118 LEU n 2 119 TYR n 2 120 ASP n 2 121 LYS n 2 122 VAL n 2 123 ARG n 2 124 LEU n 2 125 GLN n 2 126 LEU n 2 127 ARG n 2 128 ASP n 2 129 ASN n 2 130 ALA n 2 131 LYS n 2 132 GLU n 2 133 LEU n 2 134 GLY n 2 135 ASN n 2 136 GLY n 2 137 CYS n 2 138 PHE n 2 139 GLU n 2 140 PHE n 2 141 TYR n 2 142 HIS n 2 143 LYS n 2 144 CYS n 2 145 ASP n 2 146 ASN n 2 147 GLU n 2 148 CYS n 2 149 MET n 2 150 GLU n 2 151 SER n 2 152 VAL n 2 153 ARG n 2 154 ASN n 2 155 GLY n 2 156 THR n 2 157 TYR n 2 158 ASP n 2 159 TYR n 2 160 PRO n 2 161 GLN n 2 162 TYR n 2 163 SER n 2 164 GLU n 2 165 GLU n 2 166 ALA n 2 167 ARG n 2 168 LEU n 2 169 LYS n 2 170 ARG n 2 171 GLU n 2 172 GLU n 2 173 ILE n 2 174 SER n 2 175 SER n 2 176 GLY n 2 177 ARG n 3 1 GLN n 3 2 VAL n 3 3 GLN n 3 4 LEU n 3 5 VAL n 3 6 GLN n 3 7 SER n 3 8 GLY n 3 9 ALA n 3 10 GLU n 3 11 VAL n 3 12 LYS n 3 13 LYS n 3 14 PRO n 3 15 GLY n 3 16 SER n 3 17 SER n 3 18 VAL n 3 19 LYS n 3 20 VAL n 3 21 SER n 3 22 CYS n 3 23 LYS n 3 24 SER n 3 25 SER n 3 26 GLY n 3 27 GLY n 3 28 THR n 3 29 SER n 3 30 ASN n 3 31 ASN n 3 32 TYR n 3 33 ALA n 3 34 ILE n 3 35 SER n 3 36 TRP n 3 37 VAL n 3 38 ARG n 3 39 GLN n 3 40 ALA n 3 41 PRO n 3 42 GLY n 3 43 GLN n 3 44 GLY n 3 45 LEU n 3 46 ASP n 3 47 TRP n 3 48 MET n 3 49 GLY n 3 50 GLY n 3 51 ILE n 3 52 SER n 3 53 PRO n 3 54 ILE n 3 55 PHE n 3 56 GLY n 3 57 SER n 3 58 THR n 3 59 ALA n 3 60 TYR n 3 61 ALA n 3 62 GLN n 3 63 LYS n 3 64 PHE n 3 65 GLN n 3 66 GLY n 3 67 ARG n 3 68 VAL n 3 69 THR n 3 70 ILE n 3 71 SER n 3 72 ALA n 3 73 ASP n 3 74 ILE n 3 75 PHE n 3 76 SER n 3 77 ASN n 3 78 THR n 3 79 ALA n 3 80 TYR n 3 81 MET n 3 82 GLU n 3 83 LEU n 3 84 ASN n 3 85 SER n 3 86 LEU n 3 87 THR n 3 88 SER n 3 89 GLU n 3 90 ASP n 3 91 THR n 3 92 ALA n 3 93 VAL n 3 94 TYR n 3 95 PHE n 3 96 CYS n 3 97 ALA n 3 98 ARG n 3 99 HIS n 3 100 GLY n 3 101 ASN n 3 102 TYR n 3 103 TYR n 3 104 TYR n 3 105 TYR n 3 106 SER n 3 107 GLY n 3 108 MET n 3 109 ASP n 3 110 VAL n 3 111 TRP n 3 112 GLY n 3 113 GLN n 3 114 GLY n 3 115 THR n 3 116 THR n 3 117 VAL n 3 118 THR n 3 119 VAL n 3 120 SER n 3 121 SER n 3 122 ALA n 3 123 SER n 3 124 THR n 3 125 LYS n 3 126 GLY n 3 127 PRO n 3 128 SER n 3 129 VAL n 3 130 PHE n 3 131 PRO n 3 132 LEU n 3 133 ALA n 3 134 PRO n 3 135 SER n 3 136 SER n 3 137 LYS n 3 138 SER n 3 139 THR n 3 140 SER n 3 141 GLY n 3 142 GLY n 3 143 THR n 3 144 ALA n 3 145 ALA n 3 146 LEU n 3 147 GLY n 3 148 CYS n 3 149 LEU n 3 150 VAL n 3 151 LYS n 3 152 ASP n 3 153 TYR n 3 154 PHE n 3 155 PRO n 3 156 GLU n 3 157 PRO n 3 158 VAL n 3 159 THR n 3 160 VAL n 3 161 SER n 3 162 TRP n 3 163 ASN n 3 164 SER n 3 165 GLY n 3 166 ALA n 3 167 LEU n 3 168 THR n 3 169 SER n 3 170 GLY n 3 171 VAL n 3 172 HIS n 3 173 THR n 3 174 PHE n 3 175 PRO n 3 176 ALA n 3 177 VAL n 3 178 LEU n 3 179 GLN n 3 180 SER n 3 181 SER n 3 182 GLY n 3 183 LEU n 3 184 TYR n 3 185 SER n 3 186 LEU n 3 187 SER n 3 188 SER n 3 189 VAL n 3 190 VAL n 3 191 THR n 3 192 VAL n 3 193 PRO n 3 194 SER n 3 195 SER n 3 196 SER n 3 197 LEU n 3 198 GLY n 3 199 THR n 3 200 GLN n 3 201 THR n 3 202 TYR n 3 203 ILE n 3 204 CYS n 3 205 ASN n 3 206 VAL n 3 207 ASN n 3 208 HIS n 3 209 LYS n 3 210 PRO n 3 211 SER n 3 212 ASN n 3 213 THR n 3 214 LYS n 3 215 VAL n 3 216 ASP n 3 217 LYS n 3 218 ARG n 3 219 VAL n 3 220 GLU n 3 221 PRO n 3 222 LYS n 3 223 SER n 3 224 CYS n 3 225 HIS n 3 226 HIS n 3 227 HIS n 3 228 HIS n 3 229 HIS n 3 230 HIS n 4 1 GLN n 4 2 SER n 4 3 ALA n 4 4 LEU n 4 5 THR n 4 6 GLN n 4 7 PRO n 4 8 PRO n 4 9 ALA n 4 10 VAL n 4 11 SER n 4 12 GLY n 4 13 THR n 4 14 PRO n 4 15 GLY n 4 16 GLN n 4 17 ARG n 4 18 VAL n 4 19 THR n 4 20 ILE n 4 21 SER n 4 22 CYS n 4 23 SER n 4 24 GLY n 4 25 SER n 4 26 ASP n 4 27 SER n 4 28 ASN n 4 29 ILE n 4 30 GLY n 4 31 ARG n 4 32 ARG n 4 33 SER n 4 34 VAL n 4 35 ASN n 4 36 TRP n 4 37 TYR n 4 38 GLN n 4 39 GLN n 4 40 PHE n 4 41 PRO n 4 42 GLY n 4 43 THR n 4 44 ALA n 4 45 PRO n 4 46 LYS n 4 47 LEU n 4 48 LEU n 4 49 ILE n 4 50 TYR n 4 51 SER n 4 52 ASN n 4 53 ASP n 4 54 GLN n 4 55 ARG n 4 56 PRO n 4 57 SER n 4 58 VAL n 4 59 VAL n 4 60 PRO n 4 61 ASP n 4 62 ARG n 4 63 PHE n 4 64 SER n 4 65 GLY n 4 66 SER n 4 67 LYS n 4 68 SER n 4 69 GLY n 4 70 THR n 4 71 SER n 4 72 ALA n 4 73 SER n 4 74 LEU n 4 75 ALA n 4 76 ILE n 4 77 SER n 4 78 GLY n 4 79 LEU n 4 80 GLN n 4 81 SER n 4 82 GLU n 4 83 ASP n 4 84 GLU n 4 85 ALA n 4 86 GLU n 4 87 TYR n 4 88 TYR n 4 89 CYS n 4 90 ALA n 4 91 ALA n 4 92 TRP n 4 93 ASP n 4 94 ASP n 4 95 SER n 4 96 LEU n 4 97 LYS n 4 98 GLY n 4 99 ALA n 4 100 VAL n 4 101 PHE n 4 102 GLY n 4 103 GLY n 4 104 GLY n 4 105 THR n 4 106 GLN n 4 107 LEU n 4 108 THR n 4 109 VAL n 4 110 LEU n 4 111 GLY n 4 112 GLN n 4 113 PRO n 4 114 LYS n 4 115 ALA n 4 116 ALA n 4 117 PRO n 4 118 SER n 4 119 VAL n 4 120 THR n 4 121 LEU n 4 122 PHE n 4 123 PRO n 4 124 PRO n 4 125 SER n 4 126 SER n 4 127 GLU n 4 128 GLU n 4 129 LEU n 4 130 GLN n 4 131 ALA n 4 132 ASN n 4 133 LYS n 4 134 ALA n 4 135 THR n 4 136 LEU n 4 137 VAL n 4 138 CYS n 4 139 LEU n 4 140 ILE n 4 141 SER n 4 142 ASP n 4 143 PHE n 4 144 TYR n 4 145 PRO n 4 146 GLY n 4 147 ALA n 4 148 VAL n 4 149 THR n 4 150 VAL n 4 151 ALA n 4 152 TRP n 4 153 LYS n 4 154 ALA n 4 155 ASP n 4 156 SER n 4 157 SER n 4 158 PRO n 4 159 VAL n 4 160 LYS n 4 161 ALA n 4 162 GLY n 4 163 VAL n 4 164 GLU n 4 165 THR n 4 166 THR n 4 167 THR n 4 168 PRO n 4 169 SER n 4 170 LYS n 4 171 GLN n 4 172 SER n 4 173 ASN n 4 174 ASN n 4 175 LYS n 4 176 TYR n 4 177 ALA n 4 178 ALA n 4 179 SER n 4 180 SER n 4 181 TYR n 4 182 LEU n 4 183 SER n 4 184 LEU n 4 185 THR n 4 186 PRO n 4 187 GLU n 4 188 GLN n 4 189 TRP n 4 190 LYS n 4 191 SER n 4 192 HIS n 4 193 ARG n 4 194 SER n 4 195 TYR n 4 196 SER n 4 197 CYS n 4 198 GLN n 4 199 VAL n 4 200 THR n 4 201 HIS n 4 202 GLU n 4 203 GLY n 4 204 SER n 4 205 THR n 4 206 VAL n 4 207 GLU n 4 208 LYS n 4 209 THR n 4 210 VAL n 4 211 ALA n 4 212 PRO n 4 213 THR n 4 214 GLU n 4 215 CYS n 4 216 SER n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample ? ? ? ? ? HA ? 'A/Viet Nam/1203/2004(H5N1)' ? ? ? ? 'Influenza A virus' 284218 ? ? ? ? ? ? ? 'cabbage looper' 'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample ? ? ? ? ? HA ? 'A/Viet Nam/1203/2004(H5N1)' ? ? ? ? 'Influenza A virus' 284218 ? ? ? ? ? ? ? 'cabbage looper' 'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 3 1 sample ? ? ? human ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'cabbage looper' 'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 4 1 sample ? ? ? human ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'cabbage looper' 'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin _struct_ref.pdbx_db_isoform 1 UNP Q6DQ33_9INFA Q6DQ33 1 ;DQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKKHNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFINVPEWSYIV EKANPVNDLCYPGDFNDYEELKHLLSRINHFEKIQIIPKSSWSSHEASLGVSSACPYQGKSSFFRNVVWLIKKNSTYPTI KRSYNNTNQEDLLVLWGIHHPNDAAEQTKLYQNPTTYISVGTSTLNQRLVPRIATRSKVNGQSGRMEFFWTILKPNDAIN FESNGNFIAPEYAYKIVKKGDSTIMKSELEYGNCNTKCQTPMGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNS PQRERRRKKR ; 17 ? 2 UNP Q6DQ33_9INFA Q6DQ33 2 ;GLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENL NKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYDYP QYSEEARLKREEIS ; 347 ? 3 PDB 4FQI 4FQI 3 ;QVQLVQSGAEVKKPGSSVKVSCKSSGGTSNNYAISWVRQAPGQGLDWMGGISPIFGSTAYAQKFQGRVTISADIFSNTAY MELNSLTSEDTAVYFCARHGNYYYYSGMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTV SWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCHHHHHH ; 1 ? 4 PDB 4FQI 4FQI 4 ;QSALTQPPAVSGTPGQRVTISCSGSDSNIGRRSVNWYQQFPGTAPKLLIYSNDQRPSVVPDRFSGSKSGTSASLAISGLQ SEDEAEYYCAAWDDSLKGAVFGGGTQLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVK AGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS ; 1 ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4FQI A 5 ? 334 ? Q6DQ33 17 ? 346 ? 11 333 2 2 4FQI B 1 ? 174 ? Q6DQ33 347 ? 520 ? 1 174 3 3 4FQI H 1 ? 230 ? 4FQI 1 ? 222 ? 1 222 4 4 4FQI L 1 ? 216 ? 4FQI 1 ? 212 ? 1 212 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 4FQI ALA A 1 ? UNP Q6DQ33 ? ? 'EXPRESSION TAG' 7 1 1 4FQI ASP A 2 ? UNP Q6DQ33 ? ? 'EXPRESSION TAG' 8 2 1 4FQI PRO A 3 ? UNP Q6DQ33 ? ? 'EXPRESSION TAG' 9 3 1 4FQI GLY A 4 ? UNP Q6DQ33 ? ? 'EXPRESSION TAG' 10 4 2 4FQI SER B 175 ? UNP Q6DQ33 ? ? 'EXPRESSION TAG' 175 5 2 4FQI GLY B 176 ? UNP Q6DQ33 ? ? 'EXPRESSION TAG' 176 6 2 4FQI ARG B 177 ? UNP Q6DQ33 ? ? 'EXPRESSION TAG' 177 7 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 EDO non-polymer . 1,2-ETHANEDIOL 'ETHYLENE GLYCOL' 'C2 H6 O2' 62.068 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 4FQI _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 3.50 _exptl_crystal.density_percent_sol 64.85 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 7.0 _exptl_crystal_grow.pdbx_details '0.16 M sodium thiocyanate, 15% PEG3350, 100 mM Tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 75 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 315r' _diffrn_detector.pdbx_collection_date 2011-05-06 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'Side scattering I-beam bent single crystal, asymmetric cut 4.9650 degrees' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.033 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'SSRL BEAMLINE BL7-1' _diffrn_source.pdbx_synchrotron_site SSRL _diffrn_source.pdbx_synchrotron_beamline BL7-1 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.033 # _reflns.entry_id 4FQI _reflns.observed_criterion_sigma_I -3 _reflns.observed_criterion_sigma_F 0 _reflns.d_resolution_low 50 _reflns.d_resolution_high 1.71 _reflns.number_obs 158783 _reflns.number_all 158783 _reflns.percent_possible_obs 99.4 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI ? _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy ? _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 1.71 _reflns_shell.d_res_low 1.74 _reflns_shell.percent_possible_all 89.4 _reflns_shell.Rmerge_I_obs ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs ? _reflns_shell.pdbx_redundancy ? _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 4FQI _refine.ls_number_reflns_obs 157212 _refine.ls_number_reflns_all 157212 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.33 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 36.553 _refine.ls_d_res_high 1.710 _refine.ls_percent_reflns_obs 98.87 _refine.ls_R_factor_obs 0.2000 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.1983 _refine.ls_R_factor_R_free 0.2322 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.01 _refine.ls_number_reflns_R_free 7881 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean ? _refine.aniso_B[1][1] 0.1600 _refine.aniso_B[2][2] 0.1600 _refine.aniso_B[3][3] -0.0001 _refine.aniso_B[1][2] 0.0000 _refine.aniso_B[1][3] -0.0000 _refine.aniso_B[2][3] -0.0000 _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_ksol 0.354 _refine.solvent_model_param_bsol 50.052 _refine.pdbx_solvent_vdw_probe_radii 1.10 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.86 _refine.pdbx_ls_cross_valid_method ? _refine.details ? _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.56 _refine.pdbx_overall_phase_error 25.91 _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_diffrn_id 1 _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 7154 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 120 _refine_hist.number_atoms_solvent 1091 _refine_hist.number_atoms_total 8365 _refine_hist.d_res_high 1.710 _refine_hist.d_res_low 36.553 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_restraint_function _refine_ls_restr.pdbx_refine_id f_bond_d 0.018 ? ? 7634 ? 'X-RAY DIFFRACTION' f_angle_d 1.642 ? ? 10366 ? 'X-RAY DIFFRACTION' f_dihedral_angle_d 15.099 ? ? 2818 ? 'X-RAY DIFFRACTION' f_chiral_restr 0.128 ? ? 1130 ? 'X-RAY DIFFRACTION' f_plane_restr 0.008 ? ? 1352 ? 'X-RAY DIFFRACTION' # loop_ _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_all _refine_ls_shell.R_factor_all _refine_ls_shell.number_reflns_obs _refine_ls_shell.redundancy_reflns_obs _refine_ls_shell.pdbx_refine_id . 1.710 1.7296 4849 0.3511 96.0 0.3847 . . 230 . . . . 'X-RAY DIFFRACTION' . 1.7296 1.7500 4972 0.3628 99.0 0.3925 . . 236 . . . . 'X-RAY DIFFRACTION' . 1.7500 1.7713 4992 0.3433 100.0 0.4193 . . 251 . . . . 'X-RAY DIFFRACTION' . 1.7713 1.7937 4970 0.3299 100.0 0.3664 . . 259 . . . . 'X-RAY DIFFRACTION' . 1.7937 1.8173 4993 0.3239 99.0 0.4014 . . 247 . . . . 'X-RAY DIFFRACTION' . 1.8173 1.8422 4922 0.3123 99.0 0.3360 . . 293 . . . . 'X-RAY DIFFRACTION' . 1.8422 1.8685 4970 0.3085 99.0 0.3479 . . 257 . . . . 'X-RAY DIFFRACTION' . 1.8685 1.8964 4922 0.2844 99.0 0.2998 . . 270 . . . . 'X-RAY DIFFRACTION' . 1.8964 1.9260 4963 0.2864 99.0 0.3534 . . 240 . . . . 'X-RAY DIFFRACTION' . 1.9260 1.9576 4940 0.2656 99.0 0.2956 . . 249 . . . . 'X-RAY DIFFRACTION' . 1.9576 1.9914 5016 0.2297 100.0 0.2553 . . 255 . . . . 'X-RAY DIFFRACTION' . 1.9914 2.0276 5022 0.2204 100.0 0.2627 . . 229 . . . . 'X-RAY DIFFRACTION' . 2.0276 2.0666 4906 0.2248 99.0 0.2583 . . 294 . . . . 'X-RAY DIFFRACTION' . 2.0666 2.1088 5033 0.2153 100.0 0.2462 . . 259 . . . . 'X-RAY DIFFRACTION' . 2.1088 2.1546 4975 0.2022 100.0 0.2297 . . 260 . . . . 'X-RAY DIFFRACTION' . 2.1546 2.2047 4994 0.2023 99.0 0.2367 . . 280 . . . . 'X-RAY DIFFRACTION' . 2.2047 2.2598 4954 0.2111 99.0 0.2698 . . 264 . . . . 'X-RAY DIFFRACTION' . 2.2598 2.3209 4939 0.2149 98.0 0.2801 . . 261 . . . . 'X-RAY DIFFRACTION' . 2.3209 2.3892 4894 0.2072 98.0 0.2563 . . 281 . . . . 'X-RAY DIFFRACTION' . 2.3892 2.4663 4947 0.2047 98.0 0.2320 . . 247 . . . . 'X-RAY DIFFRACTION' . 2.4663 2.5545 4945 0.2112 98.0 0.2803 . . 256 . . . . 'X-RAY DIFFRACTION' . 2.5545 2.6567 4967 0.2052 98.0 0.2371 . . 263 . . . . 'X-RAY DIFFRACTION' . 2.6567 2.7776 4965 0.2006 99.0 0.2474 . . 264 . . . . 'X-RAY DIFFRACTION' . 2.7776 2.9240 4958 0.1989 98.0 0.2176 . . 289 . . . . 'X-RAY DIFFRACTION' . 2.9240 3.1071 4948 0.1911 99.0 0.2456 . . 284 . . . . 'X-RAY DIFFRACTION' . 3.1071 3.3468 5049 0.1909 99.0 0.2170 . . 281 . . . . 'X-RAY DIFFRACTION' . 3.3468 3.6833 5024 0.1738 100.0 0.2134 . . 289 . . . . 'X-RAY DIFFRACTION' . 3.6833 4.2156 5097 0.1586 100.0 0.1810 . . 260 . . . . 'X-RAY DIFFRACTION' . 4.2156 5.3087 5105 0.1448 100.0 0.1615 . . 289 . . . . 'X-RAY DIFFRACTION' . 5.3087 36.5611 5100 0.1876 95.0 0.2215 . . 244 . . . . 'X-RAY DIFFRACTION' # _struct.entry_id 4FQI _struct.title 'Crystal Structure of Fab CR9114 in Complex with a H5N1 influenza virus hemagglutinin' _struct.pdbx_descriptor 'Hemagglutinin HA1, Hemagglutinin HA2, antibody CR9114 heavy chain, antibody CR9114 light chain' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 4FQI _struct_keywords.pdbx_keywords 'VIRAL PROTEIN/IMMUNE SYSTEM' _struct_keywords.text ;neutralizing antibodies, antibody affinity, antigens, epitopes, glycosylation, hemagglutinin glycoproteins, immunoglobulin Fab fragments, H5N1 subtype, influenza vaccines, avian flu, envelope protein, VIRAL PROTEIN-IMMUNE SYSTEM complex ; # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 5 ? G N N 5 ? H N N 5 ? I N N 6 ? J N N 5 ? K N N 6 ? L N N 6 ? M N N 6 ? N N N 7 ? O N N 5 ? P N N 5 ? Q N N 5 ? R N N 5 ? S N N 5 ? T N N 6 ? U N N 5 ? V N N 8 ? W N N 8 ? X N N 8 ? Y N N 8 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 SER A 60 ? GLY A 67 ? SER A 65 GLY A 72 1 ? 8 HELX_P HELX_P2 2 ASN A 68 ? ILE A 75 ? ASN A 73 ILE A 80 5 ? 8 HELX_P HELX_P3 3 ASP A 101 ? SER A 110 ? ASP A 104 SER A 113 1 ? 10 HELX_P HELX_P4 4 PRO A 122 ? TRP A 126 ? PRO A 125 TRP A 127 5 ? 5 HELX_P HELX_P5 5 ASP A 187 ? GLN A 196 ? ASP A 187 GLN A 196 1 ? 10 HELX_P HELX_P6 6 ASP B 37 ? MET B 59 ? ASP B 37 MET B 59 1 ? 23 HELX_P HELX_P7 7 GLU B 74 ? ARG B 127 ? GLU B 74 ARG B 127 1 ? 54 HELX_P HELX_P8 8 ASP B 145 ? ASN B 154 ? ASP B 145 ASN B 154 1 ? 10 HELX_P HELX_P9 9 ASP B 158 ? GLY B 176 ? ASP B 158 GLY B 176 1 ? 19 HELX_P HELX_P10 10 GLN C 62 ? GLN C 65 ? GLN H 61 GLN H 64 5 ? 4 HELX_P HELX_P11 11 THR C 87 ? THR C 91 ? THR H 83 THR H 87 5 ? 5 HELX_P HELX_P12 12 SER C 164 ? ALA C 166 ? SER H 156 ALA H 158 5 ? 3 HELX_P HELX_P13 13 LYS C 209 ? ASN C 212 ? LYS H 201 ASN H 204 5 ? 4 HELX_P HELX_P14 14 GLN D 80 ? GLU D 84 ? GLN L 79 GLU L 83 5 ? 5 HELX_P HELX_P15 15 SER D 125 ? ALA D 131 ? SER L 121 ALA L 127 1 ? 7 HELX_P HELX_P16 16 THR D 185 ? HIS D 192 ? THR L 181 HIS L 188 1 ? 8 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 8 SG ? ? ? 1_555 B CYS 137 SG ? ? A CYS 14 B CYS 137 1_555 ? ? ? ? ? ? ? 2.182 ? disulf2 disulf ? ? A CYS 46 SG ? ? ? 1_555 A CYS 278 SG ? ? A CYS 52 A CYS 277 1_555 ? ? ? ? ? ? ? 2.094 ? disulf3 disulf ? ? A CYS 59 SG ? ? ? 1_555 A CYS 71 SG ? ? A CYS 64 A CYS 76 1_555 ? ? ? ? ? ? ? 2.172 ? disulf4 disulf ? ? A CYS 94 SG ? ? ? 1_555 A CYS 139 SG ? ? A CYS 97 A CYS 139 1_555 ? ? ? ? ? ? ? 2.188 ? disulf5 disulf ? ? A CYS 282 SG ? ? ? 1_555 A CYS 306 SG ? ? A CYS 281 A CYS 305 1_555 ? ? ? ? ? ? ? 2.120 ? disulf6 disulf ? ? B CYS 144 SG ? ? ? 1_555 B CYS 148 SG ? ? B CYS 144 B CYS 148 1_555 ? ? ? ? ? ? ? 2.222 ? disulf7 disulf ? ? C CYS 22 SG ? ? ? 1_555 C CYS 96 SG ? ? H CYS 22 H CYS 92 1_555 ? ? ? ? ? ? ? 2.172 ? disulf8 disulf ? ? C CYS 148 SG ? ? ? 1_555 C CYS 204 SG ? ? H CYS 140 H CYS 196 1_555 ? ? ? ? ? ? ? 2.038 ? disulf9 disulf ? ? D CYS 22 SG ? ? ? 1_555 D CYS 89 SG ? ? L CYS 23 L CYS 88 1_555 ? ? ? ? ? ? ? 2.158 ? disulf10 disulf ? ? D CYS 138 SG ? ? ? 1_555 D CYS 197 SG ? ? L CYS 134 L CYS 193 1_555 ? ? ? ? ? ? ? 2.041 ? covale1 covale ? ? B ASN 154 ND2 ? ? ? 1_555 T NAG . C1 ? ? B ASN 154 B NAG 207 1_555 ? ? ? ? ? ? ? 1.444 ? covale2 covale ? ? A ASN 169 ND2 ? ? ? 1_555 K NAG . C1 ? ? A ASN 169 A NAG 407 1_555 ? ? ? ? ? ? ? 1.447 ? covale3 covale ? ? A ASN 15 ND2 ? ? ? 1_555 I NAG . C1 ? ? A ASN 21 A NAG 405 1_555 ? ? ? ? ? ? ? 1.450 ? covale4 covale ? ? K NAG . O4 ? ? ? 1_555 L NAG . C1 ? ? A NAG 407 A NAG 408 1_555 ? ? ? ? ? ? ? 1.451 ? covale5 covale ? ? A ASN 27 ND2 ? ? ? 1_555 M NAG . C1 ? ? A ASN 33 A NAG 409 1_555 ? ? ? ? ? ? ? 1.464 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 154 C . ? PHE 146 H PRO 155 C ? PRO 147 H 1 -2.36 2 GLU 156 C . ? GLU 148 H PRO 157 C ? PRO 149 H 1 -0.48 3 TYR 144 D . ? TYR 140 L PRO 145 D ? PRO 141 L 1 -2.82 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 5 ? B ? 2 ? C ? 2 ? D ? 3 ? E ? 2 ? F ? 3 ? G ? 5 ? H ? 5 ? I ? 2 ? J ? 4 ? K ? 3 ? L ? 4 ? M ? 6 ? N ? 4 ? O ? 4 ? P ? 4 ? Q ? 3 ? R ? 5 ? S ? 4 ? T ? 3 ? U ? 4 ? V ? 4 ? W ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel A 4 5 ? anti-parallel B 1 2 ? anti-parallel C 1 2 ? anti-parallel D 1 2 ? parallel D 2 3 ? parallel E 1 2 ? parallel F 1 2 ? parallel F 2 3 ? parallel G 1 2 ? parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel G 4 5 ? anti-parallel H 1 2 ? parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel I 1 2 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel L 1 2 ? anti-parallel L 2 3 ? anti-parallel L 3 4 ? anti-parallel M 1 2 ? parallel M 2 3 ? anti-parallel M 3 4 ? anti-parallel M 4 5 ? anti-parallel M 5 6 ? anti-parallel N 1 2 ? parallel N 2 3 ? anti-parallel N 3 4 ? anti-parallel O 1 2 ? anti-parallel O 2 3 ? anti-parallel O 3 4 ? anti-parallel P 1 2 ? anti-parallel P 2 3 ? anti-parallel P 3 4 ? anti-parallel Q 1 2 ? anti-parallel Q 2 3 ? anti-parallel R 1 2 ? parallel R 2 3 ? anti-parallel R 3 4 ? anti-parallel R 4 5 ? anti-parallel S 1 2 ? parallel S 2 3 ? anti-parallel S 3 4 ? anti-parallel T 1 2 ? anti-parallel T 2 3 ? anti-parallel U 1 2 ? anti-parallel U 2 3 ? anti-parallel U 3 4 ? anti-parallel V 1 2 ? anti-parallel V 2 3 ? anti-parallel V 3 4 ? anti-parallel W 1 2 ? anti-parallel W 2 3 ? anti-parallel W 3 4 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 GLY B 31 ? ALA B 36 ? GLY B 31 ALA B 36 A 2 TYR B 22 ? ASN B 28 ? TYR B 22 ASN B 28 A 3 GLN A 6 ? TYR A 11 ? GLN A 12 TYR A 17 A 4 CYS B 137 ? PHE B 140 ? CYS B 137 PHE B 140 A 5 ALA B 130 ? GLU B 132 ? ALA B 130 GLU B 132 B 1 GLN A 19 ? VAL A 20 ? GLN A 25 VAL A 26 B 2 VAL A 28 ? THR A 29 ? VAL A 34 THR A 35 C 1 ALA A 33 ? ASP A 35 ? ALA A 39 ASP A 41 C 2 VAL A 316 ? ALA A 318 ? VAL A 315 ALA A 317 D 1 LEU A 37 ? GLU A 38 ? LEU A 43 GLU A 44 D 2 PHE A 295 ? HIS A 296 ? PHE A 294 HIS A 295 D 3 LYS A 308 ? TYR A 309 ? LYS A 307 TYR A 308 E 1 LEU A 45 ? LEU A 48 ? LEU A 51 LEU A 54 E 2 TYR A 275 ? THR A 280 ? TYR A 274 THR A 279 F 1 LEU A 54 ? ILE A 55 ? LEU A 59 ILE A 60 F 2 ILE A 83 ? GLU A 85 ? ILE A 87 GLU A 89 F 3 ILE A 268 ? LYS A 270 ? ILE A 267 LYS A 269 G 1 GLY A 97 ? PHE A 99 ? GLY A 100 PHE A 102 G 2 ARG A 229 ? LEU A 237 ? ARG A 229 LEU A 237 G 3 LEU A 176 ? HIS A 184 ? LEU A 176 HIS A 184 G 4 TYR A 256 ? LYS A 263 ? TYR A 256 LYS A 262 G 5 ILE A 112 ? GLN A 119 ? ILE A 115 GLN A 122 H 1 GLY A 97 ? PHE A 99 ? GLY A 100 PHE A 102 H 2 ARG A 229 ? LEU A 237 ? ARG A 229 LEU A 237 H 3 LEU A 176 ? HIS A 184 ? LEU A 176 HIS A 184 H 4 PHE A 251 ? PRO A 254 ? PHE A 251 PRO A 254 H 5 VAL A 151 ? TRP A 153 ? VAL A 151 TRP A 153 I 1 SER A 136 ? TYR A 141 ? SER A 136 TYR A 141 I 2 LYS A 144 ? SER A 146 ? LYS A 144 SER A 146 J 1 ILE A 164 ? ASN A 169 ? ILE A 164 ASN A 169 J 2 ALA A 242 ? SER A 247 ? ALA A 242 SER A 247 J 3 ILE A 202 ? GLY A 205 ? ILE A 202 GLY A 205 J 4 ASN A 210 ? LEU A 213 ? ASN A 210 LEU A 213 K 1 GLY A 287 ? ILE A 289 ? GLY A 286 ILE A 288 K 2 CYS A 282 ? THR A 284 ? CYS A 281 THR A 283 K 3 ILE A 303 ? GLY A 304 ? ILE A 302 GLY A 303 L 1 GLN C 3 ? GLN C 6 ? GLN H 3 GLN H 6 L 2 VAL C 18 ? SER C 25 ? VAL H 18 SER H 25 L 3 THR C 78 ? LEU C 83 ? THR H 77 LEU H 82 L 4 VAL C 68 ? ASP C 73 ? VAL H 67 ASP H 72 M 1 GLU C 10 ? LYS C 12 ? GLU H 10 LYS H 12 M 2 THR C 115 ? VAL C 119 ? THR H 107 VAL H 111 M 3 ALA C 92 ? HIS C 99 ? ALA H 88 HIS H 95 M 4 ILE C 34 ? GLN C 39 ? ILE H 34 GLN H 39 M 5 LEU C 45 ? SER C 52 ? LEU H 45 SER H 52 M 6 SER C 57 ? TYR C 60 ? SER H 56 TYR H 59 N 1 GLU C 10 ? LYS C 12 ? GLU H 10 LYS H 12 N 2 THR C 115 ? VAL C 119 ? THR H 107 VAL H 111 N 3 ALA C 92 ? HIS C 99 ? ALA H 88 HIS H 95 N 4 MET C 108 D TRP C 111 ? MET H 100 TRP H 103 O 1 SER C 128 ? LEU C 132 ? SER H 120 LEU H 124 O 2 THR C 143 ? TYR C 153 ? THR H 135 TYR H 145 O 3 TYR C 184 ? PRO C 193 ? TYR H 176 PRO H 185 O 4 VAL C 171 ? THR C 173 ? VAL H 163 THR H 165 P 1 SER C 128 ? LEU C 132 ? SER H 120 LEU H 124 P 2 THR C 143 ? TYR C 153 ? THR H 135 TYR H 145 P 3 TYR C 184 ? PRO C 193 ? TYR H 176 PRO H 185 P 4 VAL C 177 ? LEU C 178 ? VAL H 169 LEU H 170 Q 1 THR C 159 ? TRP C 162 ? THR H 151 TRP H 154 Q 2 ILE C 203 ? HIS C 208 ? ILE H 195 HIS H 200 Q 3 THR C 213 ? ARG C 218 ? THR H 205 ARG H 210 R 1 ALA D 9 ? GLY D 12 ? ALA L 9 GLY L 13 R 2 THR D 105 ? VAL D 109 ? THR L 102 VAL L 106 R 3 ALA D 85 ? ASP D 93 ? ALA L 84 ASP L 92 R 4 VAL D 34 ? GLN D 39 ? VAL L 33 GLN L 38 R 5 LYS D 46 ? ILE D 49 ? LYS L 45 ILE L 48 S 1 ALA D 9 ? GLY D 12 ? ALA L 9 GLY L 13 S 2 THR D 105 ? VAL D 109 ? THR L 102 VAL L 106 S 3 ALA D 85 ? ASP D 93 ? ALA L 84 ASP L 92 S 4 GLY D 98 B PHE D 101 ? GLY L 95 PHE L 98 T 1 VAL D 18 ? SER D 23 ? VAL L 19 SER L 24 T 2 SER D 71 ? ILE D 76 ? SER L 70 ILE L 75 T 3 PHE D 63 ? SER D 68 ? PHE L 62 SER L 67 U 1 SER D 118 ? PHE D 122 ? SER L 114 PHE L 118 U 2 ALA D 134 ? PHE D 143 ? ALA L 130 PHE L 139 U 3 TYR D 176 ? LEU D 184 ? TYR L 172 LEU L 180 U 4 VAL D 163 ? THR D 165 ? VAL L 159 THR L 161 V 1 SER D 118 ? PHE D 122 ? SER L 114 PHE L 118 V 2 ALA D 134 ? PHE D 143 ? ALA L 130 PHE L 139 V 3 TYR D 176 ? LEU D 184 ? TYR L 172 LEU L 180 V 4 SER D 169 ? LYS D 170 ? SER L 165 LYS L 166 W 1 SER D 157 ? PRO D 158 ? SER L 153 PRO L 154 W 2 THR D 149 ? ALA D 154 ? THR L 145 ALA L 150 W 3 TYR D 195 ? HIS D 201 ? TYR L 191 HIS L 197 W 4 SER D 204 ? VAL D 210 ? SER L 200 VAL L 206 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 O ALA B 35 ? O ALA B 35 N TYR B 24 ? N TYR B 24 A 2 3 O HIS B 25 ? O HIS B 25 N CYS A 8 ? N CYS A 14 A 3 4 N ILE A 7 ? N ILE A 13 O PHE B 138 ? O PHE B 138 A 4 5 O GLU B 139 ? O GLU B 139 N LYS B 131 ? N LYS B 131 B 1 2 N VAL A 20 ? N VAL A 26 O VAL A 28 ? O VAL A 34 C 1 2 N GLN A 34 ? N GLN A 40 O LEU A 317 ? O LEU A 316 D 1 2 N GLU A 38 ? N GLU A 44 O PHE A 295 ? O PHE A 294 D 2 3 N HIS A 296 ? N HIS A 295 O LYS A 308 ? O LYS A 307 E 1 2 N ASP A 47 ? N ASP A 53 O CYS A 278 ? O CYS A 277 F 1 2 N LEU A 54 ? N LEU A 59 O VAL A 84 ? O VAL A 88 F 2 3 N ILE A 83 ? N ILE A 87 O MET A 269 ? O MET A 268 G 1 2 N ASP A 98 ? N ASP A 101 O PHE A 232 ? O PHE A 232 G 2 3 O ARG A 229 ? O ARG A 229 N HIS A 184 ? N HIS A 184 G 3 4 N LEU A 177 ? N LEU A 177 O TYR A 258 ? O TYR A 258 G 4 5 O LYS A 262 ? O LYS A 261 N ASN A 113 ? N ASN A 116 H 1 2 N ASP A 98 ? N ASP A 101 O PHE A 232 ? O PHE A 232 H 2 3 O ARG A 229 ? O ARG A 229 N HIS A 184 ? N HIS A 184 H 3 4 N GLY A 181 ? N GLY A 181 O ILE A 252 ? O ILE A 252 H 4 5 O ALA A 253 ? O ALA A 253 N VAL A 152 ? N VAL A 152 I 1 2 N TYR A 141 ? N TYR A 141 O LYS A 144 ? O LYS A 144 J 1 2 N ILE A 164 ? N ILE A 164 O SER A 247 ? O SER A 247 J 2 3 O GLU A 246 ? O GLU A 246 N SER A 203 ? N SER A 203 J 3 4 N VAL A 204 ? N VAL A 204 O GLN A 211 ? O GLN A 211 K 1 2 O ILE A 289 ? O ILE A 288 N CYS A 282 ? N CYS A 281 K 2 3 N GLN A 283 ? N GLN A 282 O ILE A 303 ? O ILE A 302 L 1 2 N GLN C 3 ? N GLN H 3 O SER C 25 ? O SER H 25 L 2 3 N VAL C 20 ? N VAL H 20 O MET C 81 ? O MET H 80 L 3 4 O THR C 78 ? O THR H 77 N ASP C 73 ? N ASP H 72 M 1 2 N LYS C 12 ? N LYS H 12 O THR C 118 ? O THR H 110 M 2 3 O THR C 115 ? O THR H 107 N TYR C 94 ? N TYR H 90 M 3 4 O PHE C 95 ? O PHE H 91 N VAL C 37 ? N VAL H 37 M 4 5 N TRP C 36 ? N TRP H 36 O MET C 48 ? O MET H 48 M 5 6 N SER C 52 ? N SER H 52 O SER C 57 ? O SER H 56 N 1 2 N LYS C 12 ? N LYS H 12 O THR C 118 ? O THR H 110 N 2 3 O THR C 115 ? O THR H 107 N TYR C 94 ? N TYR H 90 N 3 4 N ARG C 98 ? N ARG H 94 O VAL C 110 ? O VAL H 102 O 1 2 N PHE C 130 ? N PHE H 122 O LEU C 149 ? O LEU H 141 O 2 3 N ALA C 144 ? N ALA H 136 O VAL C 192 ? O VAL H 184 O 3 4 O VAL C 189 ? O VAL H 181 N HIS C 172 ? N HIS H 164 P 1 2 N PHE C 130 ? N PHE H 122 O LEU C 149 ? O LEU H 141 P 2 3 N ALA C 144 ? N ALA H 136 O VAL C 192 ? O VAL H 184 P 3 4 O SER C 185 ? O SER H 177 N VAL C 177 ? N VAL H 169 Q 1 2 N SER C 161 ? N SER H 153 O ASN C 205 ? O ASN H 197 Q 2 3 N VAL C 206 ? N VAL H 198 O VAL C 215 ? O VAL H 207 R 1 2 N VAL D 10 ? N VAL L 11 O THR D 108 ? O THR L 105 R 2 3 O LEU D 107 ? O LEU L 104 N ALA D 85 ? N ALA L 84 R 3 4 O TYR D 88 ? O TYR L 87 N TYR D 37 ? N TYR L 36 R 4 5 N TRP D 36 ? N TRP L 35 O LEU D 48 ? O LEU L 47 S 1 2 N VAL D 10 ? N VAL L 11 O THR D 108 ? O THR L 105 S 2 3 O LEU D 107 ? O LEU L 104 N ALA D 85 ? N ALA L 84 S 3 4 N ALA D 91 ? N ALA L 90 O VAL D 100 ? O VAL L 97 T 1 2 N VAL D 18 ? N VAL L 19 O ILE D 76 ? O ILE L 75 T 2 3 O ALA D 75 ? O ALA L 74 N SER D 64 ? N SER L 63 U 1 2 N THR D 120 ? N THR L 116 O LEU D 139 ? O LEU L 135 U 2 3 N PHE D 143 ? N PHE L 139 O TYR D 176 ? O TYR L 172 U 3 4 O TYR D 181 ? O TYR L 177 N GLU D 164 ? N GLU L 160 V 1 2 N THR D 120 ? N THR L 116 O LEU D 139 ? O LEU L 135 V 2 3 N PHE D 143 ? N PHE L 139 O TYR D 176 ? O TYR L 172 V 3 4 O ALA D 177 ? O ALA L 173 N SER D 169 ? N SER L 165 W 1 2 O SER D 157 ? O SER L 153 N ALA D 154 ? N ALA L 150 W 2 3 N ALA D 151 ? N ALA L 147 O GLN D 198 ? O GLN L 194 W 3 4 N HIS D 201 ? N HIS L 197 O SER D 204 ? O SER L 200 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE EDO A 401' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE EDO A 402' AC3 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE EDO A 403' AC4 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE EDO A 404' AC5 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 405' AC6 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE EDO A 406' AC7 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 407' AC8 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 408' AC9 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 409' BC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE GOL B 201' BC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE EDO B 202' BC3 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE EDO B 203' BC4 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE EDO B 204' BC5 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE EDO B 205' BC6 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE EDO B 206' BC7 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG B 207' BC8 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE EDO H 301' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 8 VAL A 20 ? VAL A 26 . ? 1_555 ? 2 AC1 8 ASP A 21 ? ASP A 27 . ? 1_555 ? 3 AC1 8 ARG A 314 ? ARG A 313 . ? 1_555 ? 4 AC1 8 LEU A 315 ? LEU A 314 . ? 1_555 ? 5 AC1 8 VAL A 316 ? VAL A 315 . ? 1_555 ? 6 AC1 8 HOH V . ? HOH A 522 . ? 1_555 ? 7 AC1 8 VAL B 100 ? VAL B 100 . ? 1_555 ? 8 AC1 8 ASN B 104 ? ASN B 104 . ? 1_555 ? 9 AC2 5 ASP A 92 ? ASP A 96 . ? 1_555 ? 10 AC2 5 ASP A 98 ? ASP A 101 . ? 1_555 ? 11 AC2 5 PHE A 99 ? PHE A 102 . ? 1_555 ? 12 AC2 5 TYR A 102 ? TYR A 105 . ? 1_555 ? 13 AC2 5 HOH V . ? HOH A 952 . ? 1_555 ? 14 AC3 8 GLY A 97 ? GLY A 100 . ? 1_555 ? 15 AC3 8 ASP A 98 ? ASP A 101 . ? 1_555 ? 16 AC3 8 HIS A 184 ? HIS A 184 . ? 1_555 ? 17 AC3 8 ASN A 210 ? ASN A 210 . ? 2_665 ? 18 AC3 8 ARG A 216 ? ARG A 216 . ? 1_555 ? 19 AC3 8 ARG A 229 ? ARG A 229 . ? 1_555 ? 20 AC3 8 GLU A 231 ? GLU A 231 . ? 1_555 ? 21 AC3 8 HOH V . ? HOH A 857 . ? 1_555 ? 22 AC4 9 TRP A 64 ? TRP A 69 . ? 1_555 ? 23 AC4 9 PHE A 74 ? PHE A 79 . ? 1_555 ? 24 AC4 9 ILE A 75 ? ILE A 80 . ? 1_555 ? 25 AC4 9 ASN A 76 ? ASN A 81 . ? 1_555 ? 26 AC4 9 VAL A 77 ? VAL A 82 . ? 1_555 ? 27 AC4 9 LYS A 117 ? LYS A 120 . ? 1_555 ? 28 AC4 9 TYR A 258 ? TYR A 258 . ? 1_555 ? 29 AC4 9 HOH V . ? HOH A 514 . ? 1_555 ? 30 AC4 9 HOH V . ? HOH A 518 . ? 1_555 ? 31 AC5 2 ASN A 15 ? ASN A 21 . ? 1_555 ? 32 AC5 2 GLN B 15 ? GLN B 15 . ? 1_555 ? 33 AC6 7 GLN A 119 ? GLN A 122 . ? 1_555 ? 34 AC6 7 HOH V . ? HOH A 564 . ? 1_555 ? 35 AC6 7 PRO C 14 ? PRO H 14 . ? 17_554 ? 36 AC6 7 THR C 87 ? THR H 83 . ? 17_554 ? 37 AC6 7 SER C 88 ? SER H 84 . ? 17_554 ? 38 AC6 7 VAL C 119 ? VAL H 111 . ? 17_554 ? 39 AC6 7 SER C 121 ? SER H 113 . ? 17_554 ? 40 AC7 5 ASN A 169 ? ASN A 169 . ? 1_555 ? 41 AC7 5 ASN A 240 ? ASN A 240 . ? 1_555 ? 42 AC7 5 NAG L . ? NAG A 408 . ? 1_555 ? 43 AC7 5 HOH V . ? HOH A 782 . ? 1_555 ? 44 AC7 5 HOH V . ? HOH A 894 . ? 1_555 ? 45 AC8 2 ASN A 240 ? ASN A 240 . ? 1_555 ? 46 AC8 2 NAG K . ? NAG A 407 . ? 1_555 ? 47 AC9 2 ASN A 27 ? ASN A 33 . ? 1_555 ? 48 AC9 2 HOH V . ? HOH A 899 . ? 1_555 ? 49 BC1 4 HOH V . ? HOH A 504 . ? 1_555 ? 50 BC1 4 TRP B 14 ? TRP B 14 . ? 1_555 ? 51 BC1 4 EDO O . ? EDO B 202 . ? 1_555 ? 52 BC1 4 HOH W . ? HOH B 479 . ? 1_555 ? 53 BC2 3 TRP B 14 ? TRP B 14 . ? 1_555 ? 54 BC2 3 TYR B 34 ? TYR B 34 . ? 1_555 ? 55 BC2 3 GOL N . ? GOL B 201 . ? 1_555 ? 56 BC3 1 EDO Q . ? EDO B 204 . ? 1_555 ? 57 BC4 5 GLN B 42 ? GLN B 42 . ? 1_555 ? 58 BC4 5 ASP B 46 ? ASP B 46 . ? 1_555 ? 59 BC4 5 EDO P . ? EDO B 203 . ? 1_555 ? 60 BC4 5 TYR C 32 ? TYR H 32 . ? 1_555 ? 61 BC4 5 GLY C 100 ? GLY H 96 . ? 1_555 ? 62 BC5 3 ASN B 50 ? ASN B 50 . ? 1_555 ? 63 BC5 3 HOH W . ? HOH B 450 . ? 1_555 ? 64 BC5 3 ASN C 31 ? ASN H 31 . ? 1_555 ? 65 BC6 5 ALA B 36 ? ALA B 36 . ? 1_555 ? 66 BC6 5 ASP B 37 ? ASP B 37 . ? 1_555 ? 67 BC6 5 LYS B 38 ? LYS B 38 . ? 1_555 ? 68 BC6 5 GLU B 39 ? GLU B 39 . ? 1_555 ? 69 BC6 5 ARG B 153 ? ARG B 153 . ? 1_555 ? 70 BC7 4 GLU B 147 ? GLU B 147 . ? 1_555 ? 71 BC7 4 GLU B 150 ? GLU B 150 . ? 1_555 ? 72 BC7 4 ASN B 154 ? ASN B 154 . ? 1_555 ? 73 BC7 4 THR B 156 ? THR B 156 . ? 1_555 ? 74 BC8 10 ASP B 19 ? ASP B 19 . ? 1_555 ? 75 BC8 10 LYS B 38 ? LYS B 38 . ? 1_555 ? 76 BC8 10 HOH W . ? HOH B 537 . ? 1_555 ? 77 BC8 10 ASN C 101 ? ASN H 97 . ? 1_555 ? 78 BC8 10 TYR C 102 ? TYR H 98 . ? 1_555 ? 79 BC8 10 TYR C 103 ? TYR H 99 . ? 1_555 ? 80 BC8 10 TYR C 105 A TYR H 100 . ? 1_555 ? 81 BC8 10 HOH X . ? HOH H 417 . ? 1_555 ? 82 BC8 10 HOH X . ? HOH H 569 . ? 1_555 ? 83 BC8 10 HOH X . ? HOH H 570 . ? 1_555 ? # _database_PDB_matrix.entry_id 4FQI _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 4FQI _atom_sites.fract_transf_matrix[1][1] 0.007060 _atom_sites.fract_transf_matrix[1][2] 0.004076 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.008152 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.002611 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ASP A 1 2 ? 0.166 64.170 13.148 1.00 69.40 ? 8 ASP A N 1 ATOM 2 C CA . ASP A 1 2 ? -0.141 63.012 12.310 1.00 78.07 ? 8 ASP A CA 1 ATOM 3 C C . ASP A 1 2 ? -0.578 63.447 10.917 1.00 61.73 ? 8 ASP A C 1 ATOM 4 O O . ASP A 1 2 ? -1.331 64.416 10.794 1.00 57.31 ? 8 ASP A O 1 ATOM 5 C CB . ASP A 1 2 ? -1.211 62.141 12.969 1.00 81.99 ? 8 ASP A CB 1 ATOM 6 C CG . ASP A 1 2 ? -0.614 61.134 13.936 1.00 103.42 ? 8 ASP A CG 1 ATOM 7 O OD1 . ASP A 1 2 ? 0.482 61.407 14.482 1.00 104.26 ? 8 ASP A OD1 1 ATOM 8 O OD2 . ASP A 1 2 ? -1.232 60.066 14.138 1.00 106.66 ? 8 ASP A OD2 1 ATOM 9 N N . PRO A 1 3 ? -0.101 62.737 9.874 1.00 64.62 ? 9 PRO A N 1 ATOM 10 C CA . PRO A 1 3 ? -0.258 63.177 8.479 1.00 55.35 ? 9 PRO A CA 1 ATOM 11 C C . PRO A 1 3 ? -1.730 63.279 8.121 1.00 50.11 ? 9 PRO A C 1 ATOM 12 O O . PRO A 1 3 ? -2.550 62.456 8.520 1.00 49.88 ? 9 PRO A O 1 ATOM 13 C CB . PRO A 1 3 ? 0.407 62.057 7.682 1.00 57.68 ? 9 PRO A CB 1 ATOM 14 C CG . PRO A 1 3 ? 0.269 60.857 8.557 1.00 64.24 ? 9 PRO A CG 1 ATOM 15 C CD . PRO A 1 3 ? 0.485 61.386 9.947 1.00 65.34 ? 9 PRO A CD 1 ATOM 16 N N . GLY A 1 4 ? -2.074 64.323 7.397 1.00 36.31 ? 10 GLY A N 1 ATOM 17 C CA . GLY A 1 4 ? -3.472 64.556 7.121 1.00 32.00 ? 10 GLY A CA 1 ATOM 18 C C . GLY A 1 4 ? -3.896 63.894 5.812 1.00 26.24 ? 10 GLY A C 1 ATOM 19 O O . GLY A 1 4 ? -3.086 63.353 5.063 1.00 28.27 ? 10 GLY A O 1 ATOM 20 N N . ASP A 1 5 ? -5.183 63.963 5.547 1.00 23.43 ? 11 ASP A N 1 ATOM 21 C CA . ASP A 1 5 ? -5.716 63.462 4.276 1.00 22.07 ? 11 ASP A CA 1 ATOM 22 C C . ASP A 1 5 ? -5.095 64.341 3.161 1.00 26.56 ? 11 ASP A C 1 ATOM 23 O O . ASP A 1 5 ? -4.647 65.468 3.440 1.00 23.83 ? 11 ASP A O 1 ATOM 24 C CB . ASP A 1 5 ? -7.219 63.669 4.310 1.00 25.99 ? 11 ASP A CB 1 ATOM 25 C CG . ASP A 1 5 ? -7.921 62.808 5.409 1.00 25.11 ? 11 ASP A CG 1 ATOM 26 O OD1 . ASP A 1 5 ? -7.310 61.788 5.758 1.00 26.83 ? 11 ASP A OD1 1 ATOM 27 O OD2 . ASP A 1 5 ? -9.020 63.198 5.883 1.00 29.14 ? 11 ASP A OD2 1 ATOM 28 N N . GLN A 1 6 ? -5.036 63.816 1.931 1.00 24.48 ? 12 GLN A N 1 ATOM 29 C CA . GLN A 1 6 ? -4.452 64.570 0.810 1.00 21.26 ? 12 GLN A CA 1 ATOM 30 C C . GLN A 1 6 ? -5.353 64.542 -0.425 1.00 25.33 ? 12 GLN A C 1 ATOM 31 O O . GLN A 1 6 ? -6.065 63.558 -0.675 1.00 23.18 ? 12 GLN A O 1 ATOM 32 C CB . GLN A 1 6 ? -3.084 64.019 0.435 1.00 22.41 ? 12 GLN A CB 1 ATOM 33 C CG . GLN A 1 6 ? -1.998 64.428 1.426 1.00 27.79 ? 12 GLN A CG 1 ATOM 34 C CD . GLN A 1 6 ? -0.559 64.134 0.915 1.00 36.30 ? 12 GLN A CD 1 ATOM 35 O OE1 . GLN A 1 6 ? -0.294 64.125 -0.291 1.00 30.99 ? 12 GLN A OE1 1 ATOM 36 N NE2 . GLN A 1 6 ? 0.386 63.986 1.855 1.00 35.38 ? 12 GLN A NE2 1 ATOM 37 N N . ILE A 1 7 ? -5.279 65.606 -1.220 1.00 22.60 ? 13 ILE A N 1 ATOM 38 C CA . ILE A 1 7 ? -5.749 65.467 -2.632 1.00 19.13 ? 13 ILE A CA 1 ATOM 39 C C . ILE A 1 7 ? -4.671 65.994 -3.534 1.00 21.31 ? 13 ILE A C 1 ATOM 40 O O . ILE A 1 7 ? -4.017 66.998 -3.218 1.00 21.16 ? 13 ILE A O 1 ATOM 41 C CB . ILE A 1 7 ? -7.083 66.158 -2.850 1.00 22.66 ? 13 ILE A CB 1 ATOM 42 C CG1 . ILE A 1 7 ? -7.657 65.798 -4.240 1.00 21.97 ? 13 ILE A CG1 1 ATOM 43 C CG2 . ILE A 1 7 ? -6.982 67.710 -2.620 1.00 21.43 ? 13 ILE A CG2 1 ATOM 44 C CD1 . ILE A 1 7 ? -9.091 66.229 -4.359 1.00 22.99 ? 13 ILE A CD1 1 ATOM 45 N N . CYS A 1 8 ? -4.466 65.337 -4.685 1.00 18.67 ? 14 CYS A N 1 ATOM 46 C CA . CYS A 1 8 ? -3.417 65.740 -5.604 1.00 18.55 ? 14 CYS A CA 1 ATOM 47 C C . CYS A 1 8 ? -4.071 65.991 -6.949 1.00 23.05 ? 14 CYS A C 1 ATOM 48 O O . CYS A 1 8 ? -5.037 65.321 -7.288 1.00 21.24 ? 14 CYS A O 1 ATOM 49 C CB . CYS A 1 8 ? -2.398 64.621 -5.820 1.00 25.03 ? 14 CYS A CB 1 ATOM 50 S SG . CYS A 1 8 ? -1.597 64.153 -4.219 1.00 30.16 ? 14 CYS A SG 1 ATOM 51 N N . ILE A 1 9 ? -3.456 66.892 -7.721 1.00 19.58 ? 15 ILE A N 1 ATOM 52 C CA . ILE A 1 9 ? -3.881 67.170 -9.092 1.00 16.70 ? 15 ILE A CA 1 ATOM 53 C C . ILE A 1 9 ? -2.851 66.582 -10.041 1.00 19.32 ? 15 ILE A C 1 ATOM 54 O O . ILE A 1 9 ? -1.656 66.671 -9.824 1.00 20.16 ? 15 ILE A O 1 ATOM 55 C CB . ILE A 1 9 ? -4.053 68.729 -9.315 1.00 19.78 ? 15 ILE A CB 1 ATOM 56 C CG1 . ILE A 1 9 ? -5.346 69.183 -8.590 1.00 21.82 ? 15 ILE A CG1 1 ATOM 57 C CG2 . ILE A 1 9 ? -4.154 69.013 -10.845 1.00 23.91 ? 15 ILE A CG2 1 ATOM 58 C CD1 . ILE A 1 9 ? -5.136 69.348 -7.071 1.00 32.80 ? 15 ILE A CD1 1 ATOM 59 N N . GLY A 1 10 ? -3.310 65.924 -11.122 1.00 18.89 ? 16 GLY A N 1 ATOM 60 C CA . GLY A 1 10 ? -2.339 65.312 -12.020 1.00 19.86 ? 16 GLY A CA 1 ATOM 61 C C . GLY A 1 10 ? -2.994 65.127 -13.387 1.00 19.08 ? 16 GLY A C 1 ATOM 62 O O . GLY A 1 10 ? -4.112 65.630 -13.623 1.00 18.01 ? 16 GLY A O 1 ATOM 63 N N . TYR A 1 11 ? -2.324 64.400 -14.270 1.00 20.05 ? 17 TYR A N 1 ATOM 64 C CA . TYR A 1 11 ? -2.757 64.365 -15.668 1.00 19.68 ? 17 TYR A CA 1 ATOM 65 C C . TYR A 1 11 ? -2.392 63.022 -16.261 1.00 21.18 ? 17 TYR A C 1 ATOM 66 O O . TYR A 1 11 ? -1.577 62.295 -15.710 1.00 20.07 ? 17 TYR A O 1 ATOM 67 C CB . TYR A 1 11 ? -2.154 65.532 -16.517 1.00 17.58 ? 17 TYR A CB 1 ATOM 68 C CG . TYR A 1 11 ? -0.626 65.609 -16.382 1.00 17.90 ? 17 TYR A CG 1 ATOM 69 C CD1 . TYR A 1 11 ? 0.216 64.915 -17.275 1.00 20.10 ? 17 TYR A CD1 1 ATOM 70 C CD2 . TYR A 1 11 ? -0.043 66.319 -15.328 1.00 19.47 ? 17 TYR A CD2 1 ATOM 71 C CE1 . TYR A 1 11 ? 1.632 64.993 -17.146 1.00 21.79 ? 17 TYR A CE1 1 ATOM 72 C CE2 . TYR A 1 11 ? 1.363 66.415 -15.189 1.00 22.50 ? 17 TYR A CE2 1 ATOM 73 C CZ . TYR A 1 11 ? 2.177 65.716 -16.091 1.00 25.27 ? 17 TYR A CZ 1 ATOM 74 O OH . TYR A 1 11 ? 3.545 65.746 -15.930 1.00 25.86 ? 17 TYR A OH 1 ATOM 75 N N . HIS A 1 12 ? -3.046 62.713 -17.364 1.00 17.56 ? 18 HIS A N 1 ATOM 76 C CA . HIS A 1 12 ? -2.912 61.391 -18.028 1.00 19.80 ? 18 HIS A CA 1 ATOM 77 C C . HIS A 1 12 ? -1.544 61.121 -18.604 1.00 21.84 ? 18 HIS A C 1 ATOM 78 O O . HIS A 1 12 ? -0.942 61.982 -19.237 1.00 23.01 ? 18 HIS A O 1 ATOM 79 C CB . HIS A 1 12 ? -3.976 61.355 -19.113 1.00 23.24 ? 18 HIS A CB 1 ATOM 80 C CG . HIS A 1 12 ? -3.945 60.149 -19.999 1.00 26.98 ? 18 HIS A CG 1 ATOM 81 N ND1 . HIS A 1 12 ? -4.299 58.885 -19.545 1.00 29.97 ? 18 HIS A ND1 1 ATOM 82 C CD2 . HIS A 1 12 ? -3.665 60.017 -21.317 1.00 33.64 ? 18 HIS A CD2 1 ATOM 83 C CE1 . HIS A 1 12 ? -4.228 58.027 -20.555 1.00 26.82 ? 18 HIS A CE1 1 ATOM 84 N NE2 . HIS A 1 12 ? -3.831 58.682 -21.633 1.00 29.35 ? 18 HIS A NE2 1 ATOM 85 N N . ALA A 1 13 ? -1.045 59.892 -18.412 1.00 18.10 ? 19 ALA A N 1 ATOM 86 C CA . ALA A 1 13 ? 0.200 59.421 -19.053 1.00 21.07 ? 19 ALA A CA 1 ATOM 87 C C . ALA A 1 13 ? -0.112 58.003 -19.537 1.00 20.73 ? 19 ALA A C 1 ATOM 88 O O . ALA A 1 13 ? -1.033 57.384 -19.042 1.00 22.53 ? 19 ALA A O 1 ATOM 89 C CB . ALA A 1 13 ? 1.373 59.385 -18.078 1.00 23.52 ? 19 ALA A CB 1 ATOM 90 N N . ASN A 1 14 ? 0.655 57.573 -20.526 1.00 20.39 ? 20 ASN A N 1 ATOM 91 C CA . ASN A 1 14 ? 0.469 56.200 -21.043 1.00 25.11 ? 20 ASN A CA 1 ATOM 92 C C . ASN A 1 14 ? 1.762 55.691 -21.637 1.00 20.92 ? 20 ASN A C 1 ATOM 93 O O . ASN A 1 14 ? 2.855 56.238 -21.399 1.00 24.44 ? 20 ASN A O 1 ATOM 94 C CB . ASN A 1 14 ? -0.763 56.149 -22.008 1.00 20.90 ? 20 ASN A CB 1 ATOM 95 C CG . ASN A 1 14 ? -0.510 56.902 -23.302 1.00 21.43 ? 20 ASN A CG 1 ATOM 96 O OD1 . ASN A 1 14 ? 0.628 57.314 -23.564 1.00 21.37 ? 20 ASN A OD1 1 ATOM 97 N ND2 . ASN A 1 14 ? -1.560 57.036 -24.138 1.00 22.17 ? 20 ASN A ND2 1 ATOM 98 N N . ASN A 1 15 ? 1.692 54.575 -22.398 1.00 23.42 ? 21 ASN A N 1 ATOM 99 C CA . ASN A 1 15 ? 2.926 54.062 -22.948 1.00 24.95 ? 21 ASN A CA 1 ATOM 100 C C . ASN A 1 15 ? 3.183 54.408 -24.400 1.00 26.75 ? 21 ASN A C 1 ATOM 101 O O . ASN A 1 15 ? 4.008 53.787 -25.069 1.00 26.52 ? 21 ASN A O 1 ATOM 102 C CB . ASN A 1 15 ? 2.977 52.530 -22.720 1.00 26.85 ? 21 ASN A CB 1 ATOM 103 C CG . ASN A 1 15 ? 3.066 52.214 -21.228 1.00 32.34 ? 21 ASN A CG 1 ATOM 104 O OD1 . ASN A 1 15 ? 3.886 52.837 -20.496 1.00 37.07 ? 21 ASN A OD1 1 ATOM 105 N ND2 . ASN A 1 15 ? 2.240 51.291 -20.765 1.00 46.22 ? 21 ASN A ND2 1 ATOM 106 N N . SER A 1 16 ? 2.500 55.431 -24.882 1.00 24.88 ? 22 SER A N 1 ATOM 107 C CA . SER A 1 16 ? 2.652 55.880 -26.257 1.00 21.46 ? 22 SER A CA 1 ATOM 108 C C . SER A 1 16 ? 4.056 56.311 -26.548 1.00 25.02 ? 22 SER A C 1 ATOM 109 O O . SER A 1 16 ? 4.678 57.004 -25.770 1.00 22.42 ? 22 SER A O 1 ATOM 110 C CB . SER A 1 16 ? 1.665 57.062 -26.576 1.00 20.42 ? 22 SER A CB 1 ATOM 111 O OG . SER A 1 16 ? 1.912 57.642 -27.884 1.00 22.18 ? 22 SER A OG 1 ATOM 112 N N . THR A 1 17 ? 4.543 55.939 -27.731 1.00 23.10 ? 23 THR A N 1 ATOM 113 C CA . THR A 1 17 ? 5.803 56.495 -28.218 1.00 23.91 ? 23 THR A CA 1 ATOM 114 C C . THR A 1 17 ? 5.594 57.348 -29.460 1.00 22.18 ? 23 THR A C 1 ATOM 115 O O . THR A 1 17 ? 6.552 57.695 -30.149 1.00 25.11 ? 23 THR A O 1 ATOM 116 C CB . THR A 1 17 ? 6.815 55.381 -28.588 1.00 33.31 ? 23 THR A CB 1 ATOM 117 O OG1 . THR A 1 17 ? 6.217 54.540 -29.577 1.00 28.82 ? 23 THR A OG1 1 ATOM 118 C CG2 . THR A 1 17 ? 7.218 54.561 -27.340 1.00 34.12 ? 23 THR A CG2 1 ATOM 119 N N . GLU A 1 18 ? 4.356 57.706 -29.746 1.00 22.06 ? 24 GLU A N 1 ATOM 120 C CA . GLU A 1 18 ? 4.078 58.589 -30.883 1.00 23.79 ? 24 GLU A CA 1 ATOM 121 C C . GLU A 1 18 ? 4.676 59.977 -30.659 1.00 23.39 ? 24 GLU A C 1 ATOM 122 O O . GLU A 1 18 ? 4.681 60.455 -29.529 1.00 22.37 ? 24 GLU A O 1 ATOM 123 C CB . GLU A 1 18 ? 2.560 58.748 -31.078 1.00 24.48 ? 24 GLU A CB 1 ATOM 124 C CG . GLU A 1 18 ? 1.856 57.439 -31.368 1.00 37.70 ? 24 GLU A CG 1 ATOM 125 C CD . GLU A 1 18 ? 2.501 56.654 -32.533 1.00 50.72 ? 24 GLU A CD 1 ATOM 126 O OE1 . GLU A 1 18 ? 2.862 57.286 -33.563 1.00 55.26 ? 24 GLU A OE1 1 ATOM 127 O OE2 . GLU A 1 18 ? 2.663 55.407 -32.404 1.00 71.86 ? 24 GLU A OE2 1 ATOM 128 N N . GLN A 1 19 ? 5.195 60.586 -31.730 1.00 21.27 ? 25 GLN A N 1 ATOM 129 C CA . GLN A 1 19 ? 5.860 61.876 -31.574 1.00 22.12 ? 25 GLN A CA 1 ATOM 130 C C . GLN A 1 19 ? 5.271 62.927 -32.516 1.00 23.15 ? 25 GLN A C 1 ATOM 131 O O . GLN A 1 19 ? 4.775 62.620 -33.603 1.00 21.36 ? 25 GLN A O 1 ATOM 132 C CB . GLN A 1 19 ? 7.335 61.749 -31.933 1.00 24.56 ? 25 GLN A CB 1 ATOM 133 C CG . GLN A 1 19 ? 8.095 60.879 -30.880 1.00 25.73 ? 25 GLN A CG 1 ATOM 134 C CD . GLN A 1 19 ? 9.566 60.720 -31.282 1.00 32.48 ? 25 GLN A CD 1 ATOM 135 O OE1 . GLN A 1 19 ? 9.933 61.065 -32.379 1.00 34.69 ? 25 GLN A OE1 1 ATOM 136 N NE2 . GLN A 1 19 ? 10.387 60.200 -30.387 1.00 40.58 ? 25 GLN A NE2 1 ATOM 137 N N . VAL A 1 20 ? 5.317 64.180 -32.090 1.00 18.17 ? 26 VAL A N 1 ATOM 138 C CA . VAL A 1 20 ? 4.970 65.269 -33.014 1.00 16.86 ? 26 VAL A CA 1 ATOM 139 C C . VAL A 1 20 ? 6.045 66.357 -32.957 1.00 19.52 ? 26 VAL A C 1 ATOM 140 O O . VAL A 1 20 ? 6.914 66.395 -32.023 1.00 20.79 ? 26 VAL A O 1 ATOM 141 C CB . VAL A 1 20 ? 3.623 65.958 -32.589 1.00 17.03 ? 26 VAL A CB 1 ATOM 142 C CG1 . VAL A 1 20 ? 2.420 64.889 -32.573 1.00 19.92 ? 26 VAL A CG1 1 ATOM 143 C CG2 . VAL A 1 20 ? 3.797 66.619 -31.182 1.00 18.06 ? 26 VAL A CG2 1 ATOM 144 N N . ASP A 1 21 ? 5.982 67.263 -33.934 1.00 19.50 ? 27 ASP A N 1 ATOM 145 C CA . ASP A 1 21 ? 6.908 68.420 -33.943 1.00 20.46 ? 27 ASP A CA 1 ATOM 146 C C . ASP A 1 21 ? 6.149 69.726 -33.675 1.00 19.44 ? 27 ASP A C 1 ATOM 147 O O . ASP A 1 21 ? 4.952 69.846 -33.955 1.00 18.94 ? 27 ASP A O 1 ATOM 148 C CB . ASP A 1 21 ? 7.602 68.578 -35.301 1.00 20.84 ? 27 ASP A CB 1 ATOM 149 C CG . ASP A 1 21 ? 8.467 67.375 -35.655 1.00 24.57 ? 27 ASP A CG 1 ATOM 150 O OD1 . ASP A 1 21 ? 8.962 66.684 -34.737 1.00 23.73 ? 27 ASP A OD1 1 ATOM 151 O OD2 . ASP A 1 21 ? 8.690 67.141 -36.867 1.00 29.08 ? 27 ASP A OD2 1 ATOM 152 N N . THR A 1 22 ? 6.867 70.676 -33.055 1.00 17.73 ? 28 THR A N 1 ATOM 153 C CA . THR A 1 22 ? 6.340 72.004 -32.838 1.00 16.32 ? 28 THR A CA 1 ATOM 154 C C . THR A 1 22 ? 7.350 72.995 -33.436 1.00 21.06 ? 28 THR A C 1 ATOM 155 O O . THR A 1 22 ? 8.329 72.606 -34.044 1.00 23.58 ? 28 THR A O 1 ATOM 156 C CB . THR A 1 22 ? 6.156 72.325 -31.323 1.00 20.36 ? 28 THR A CB 1 ATOM 157 O OG1 . THR A 1 22 ? 7.439 72.327 -30.683 1.00 22.19 ? 28 THR A OG1 1 ATOM 158 C CG2 . THR A 1 22 ? 5.272 71.232 -30.607 1.00 22.05 ? 28 THR A CG2 1 ATOM 159 N N . ILE A 1 23 ? 7.125 74.289 -33.260 1.00 19.00 ? 29 ILE A N 1 ATOM 160 C CA . ILE A 1 23 ? 8.087 75.264 -33.743 1.00 18.99 ? 29 ILE A CA 1 ATOM 161 C C . ILE A 1 23 ? 9.407 75.197 -32.932 1.00 19.58 ? 29 ILE A C 1 ATOM 162 O O . ILE A 1 23 ? 10.504 75.210 -33.524 1.00 21.79 ? 29 ILE A O 1 ATOM 163 C CB . ILE A 1 23 ? 7.478 76.701 -33.597 1.00 22.41 ? 29 ILE A CB 1 ATOM 164 C CG1 . ILE A 1 23 ? 6.347 76.875 -34.660 1.00 26.72 ? 29 ILE A CG1 1 ATOM 165 C CG2 . ILE A 1 23 ? 8.540 77.775 -33.848 1.00 24.84 ? 29 ILE A CG2 1 ATOM 166 C CD1 . ILE A 1 23 ? 6.811 76.915 -36.070 1.00 25.45 ? 29 ILE A CD1 1 ATOM 167 N N . MET A 1 24 ? 9.288 75.091 -31.604 1.00 17.88 ? 30 MET A N 1 ATOM 168 C CA . MET A 1 24 ? 10.491 75.166 -30.735 1.00 19.29 ? 30 MET A CA 1 ATOM 169 C C . MET A 1 24 ? 11.103 73.820 -30.405 1.00 21.18 ? 30 MET A C 1 ATOM 170 O O . MET A 1 24 ? 12.177 73.764 -29.835 1.00 20.81 ? 30 MET A O 1 ATOM 171 C CB . MET A 1 24 ? 10.163 75.913 -29.409 1.00 17.53 ? 30 MET A CB 1 ATOM 172 C CG . MET A 1 24 ? 9.892 77.399 -29.736 1.00 18.57 ? 30 MET A CG 1 ATOM 173 S SD . MET A 1 24 ? 10.149 78.324 -28.180 1.00 22.88 ? 30 MET A SD 1 ATOM 174 C CE . MET A 1 24 ? 8.911 77.572 -27.080 1.00 22.36 ? 30 MET A CE 1 ATOM 175 N N A GLU A 1 25 ? 10.410 72.732 -30.734 0.54 20.57 ? 31 GLU A N 1 ATOM 176 N N B GLU A 1 25 ? 10.414 72.719 -30.705 0.46 20.58 ? 31 GLU A N 1 ATOM 177 C CA A GLU A 1 25 ? 10.833 71.408 -30.289 0.54 20.41 ? 31 GLU A CA 1 ATOM 178 C CA B GLU A 1 25 ? 10.928 71.410 -30.291 0.46 20.41 ? 31 GLU A CA 1 ATOM 179 C C A GLU A 1 25 ? 10.561 70.420 -31.398 0.54 20.88 ? 31 GLU A C 1 ATOM 180 C C B GLU A 1 25 ? 10.470 70.283 -31.187 0.46 22.06 ? 31 GLU A C 1 ATOM 181 O O A GLU A 1 25 ? 9.584 70.579 -32.091 0.54 23.80 ? 31 GLU A O 1 ATOM 182 O O B GLU A 1 25 ? 9.272 70.180 -31.462 0.46 17.30 ? 31 GLU A O 1 ATOM 183 C CB A GLU A 1 25 ? 10.043 70.988 -29.041 0.54 17.94 ? 31 GLU A CB 1 ATOM 184 C CB B GLU A 1 25 ? 10.512 71.069 -28.855 0.46 21.46 ? 31 GLU A CB 1 ATOM 185 C CG A GLU A 1 25 ? 10.321 71.886 -27.814 0.54 20.34 ? 31 GLU A CG 1 ATOM 186 C CG B GLU A 1 25 ? 11.220 69.831 -28.336 0.46 26.65 ? 31 GLU A CG 1 ATOM 187 C CD A GLU A 1 25 ? 9.537 71.434 -26.591 0.54 31.22 ? 31 GLU A CD 1 ATOM 188 C CD B GLU A 1 25 ? 10.926 69.477 -26.894 0.46 26.60 ? 31 GLU A CD 1 ATOM 189 O OE1 A GLU A 1 25 ? 9.874 70.384 -26.011 0.54 29.48 ? 31 GLU A OE1 1 ATOM 190 O OE1 B GLU A 1 25 ? 10.165 70.199 -26.219 0.46 30.61 ? 31 GLU A OE1 1 ATOM 191 O OE2 A GLU A 1 25 ? 8.601 72.141 -26.210 0.54 33.75 ? 31 GLU A OE2 1 ATOM 192 O OE2 B GLU A 1 25 ? 11.487 68.462 -26.441 0.46 28.46 ? 31 GLU A OE2 1 ATOM 193 N N . LYS A 1 26 ? 11.402 69.391 -31.554 1.00 22.42 ? 32 LYS A N 1 ATOM 194 C CA . LYS A 1 26 ? 11.072 68.298 -32.456 1.00 20.83 ? 32 LYS A CA 1 ATOM 195 C C . LYS A 1 26 ? 10.971 66.969 -31.699 1.00 21.15 ? 32 LYS A C 1 ATOM 196 O O . LYS A 1 26 ? 11.555 66.816 -30.604 1.00 23.73 ? 32 LYS A O 1 ATOM 197 C CB . LYS A 1 26 ? 12.167 68.148 -33.543 1.00 26.33 ? 32 LYS A CB 1 ATOM 198 C CG . LYS A 1 26 ? 12.531 69.495 -34.215 1.00 31.61 ? 32 LYS A CG 1 ATOM 199 C CD . LYS A 1 26 ? 11.331 70.150 -34.848 1.00 31.60 ? 32 LYS A CD 1 ATOM 200 C CE . LYS A 1 26 ? 11.540 71.646 -35.212 1.00 36.34 ? 32 LYS A CE 1 ATOM 201 N NZ . LYS A 1 26 ? 10.359 72.294 -35.936 1.00 33.25 ? 32 LYS A NZ 1 ATOM 202 N N . ASN A 1 27 ? 10.230 66.019 -32.268 1.00 21.64 ? 33 ASN A N 1 ATOM 203 C CA . ASN A 1 27 ? 10.178 64.638 -31.740 1.00 21.42 ? 33 ASN A CA 1 ATOM 204 C C . ASN A 1 27 ? 9.702 64.629 -30.302 1.00 23.33 ? 33 ASN A C 1 ATOM 205 O O . ASN A 1 27 ? 10.317 64.013 -29.394 1.00 24.42 ? 33 ASN A O 1 ATOM 206 C CB . ASN A 1 27 ? 11.544 63.967 -31.834 1.00 25.64 ? 33 ASN A CB 1 ATOM 207 C CG . ASN A 1 27 ? 11.915 63.646 -33.275 1.00 38.49 ? 33 ASN A CG 1 ATOM 208 O OD1 . ASN A 1 27 ? 11.083 63.783 -34.164 1.00 37.74 ? 33 ASN A OD1 1 ATOM 209 N ND2 . ASN A 1 27 ? 13.160 63.229 -33.498 1.00 49.61 ? 33 ASN A ND2 1 ATOM 210 N N . VAL A 1 28 ? 8.622 65.373 -30.075 1.00 20.94 ? 34 VAL A N 1 ATOM 211 C CA . VAL A 1 28 ? 8.005 65.390 -28.755 1.00 19.60 ? 34 VAL A CA 1 ATOM 212 C C . VAL A 1 28 ? 7.083 64.200 -28.578 1.00 18.34 ? 34 VAL A C 1 ATOM 213 O O . VAL A 1 28 ? 6.145 64.035 -29.321 1.00 22.82 ? 34 VAL A O 1 ATOM 214 C CB . VAL A 1 28 ? 7.184 66.712 -28.551 1.00 19.05 ? 34 VAL A CB 1 ATOM 215 C CG1 . VAL A 1 28 ? 6.494 66.685 -27.178 1.00 23.17 ? 34 VAL A CG1 1 ATOM 216 C CG2 . VAL A 1 28 ? 8.161 67.930 -28.674 1.00 21.86 ? 34 VAL A CG2 1 ATOM 217 N N . THR A 1 29 ? 7.370 63.359 -27.579 1.00 19.14 ? 35 THR A N 1 ATOM 218 C CA . THR A 1 29 ? 6.500 62.220 -27.346 1.00 19.04 ? 35 THR A CA 1 ATOM 219 C C . THR A 1 29 ? 5.173 62.639 -26.703 1.00 21.21 ? 35 THR A C 1 ATOM 220 O O . THR A 1 29 ? 5.164 63.429 -25.745 1.00 19.83 ? 35 THR A O 1 ATOM 221 C CB . THR A 1 29 ? 7.212 61.128 -26.500 1.00 23.40 ? 35 THR A CB 1 ATOM 222 O OG1 . THR A 1 29 ? 8.441 60.814 -27.161 1.00 24.24 ? 35 THR A OG1 1 ATOM 223 C CG2 . THR A 1 29 ? 6.290 59.904 -26.396 1.00 21.87 ? 35 THR A CG2 1 ATOM 224 N N . VAL A 1 30 ? 4.063 62.166 -27.257 1.00 20.46 ? 36 VAL A N 1 ATOM 225 C CA . VAL A 1 30 ? 2.719 62.534 -26.755 1.00 20.45 ? 36 VAL A CA 1 ATOM 226 C C . VAL A 1 30 ? 1.842 61.311 -26.486 1.00 19.73 ? 36 VAL A C 1 ATOM 227 O O . VAL A 1 30 ? 2.140 60.244 -26.982 1.00 21.15 ? 36 VAL A O 1 ATOM 228 C CB . VAL A 1 30 ? 1.974 63.452 -27.773 1.00 17.75 ? 36 VAL A CB 1 ATOM 229 C CG1 . VAL A 1 30 ? 2.722 64.796 -27.901 1.00 19.58 ? 36 VAL A CG1 1 ATOM 230 C CG2 . VAL A 1 30 ? 1.862 62.795 -29.152 1.00 19.88 ? 36 VAL A CG2 1 ATOM 231 N N . THR A 1 31 ? 0.793 61.461 -25.698 1.00 17.83 ? 37 THR A N 1 ATOM 232 C CA . THR A 1 31 ? -0.092 60.386 -25.315 1.00 21.04 ? 37 THR A CA 1 ATOM 233 C C . THR A 1 31 ? -0.870 59.896 -26.510 1.00 23.20 ? 37 THR A C 1 ATOM 234 O O . THR A 1 31 ? -1.145 58.702 -26.622 1.00 21.35 ? 37 THR A O 1 ATOM 235 C CB . THR A 1 31 ? -1.075 60.737 -24.192 1.00 21.50 ? 37 THR A CB 1 ATOM 236 O OG1 . THR A 1 31 ? -1.907 61.841 -24.571 1.00 21.35 ? 37 THR A OG1 1 ATOM 237 C CG2 . THR A 1 31 ? -0.282 61.073 -22.860 1.00 21.48 ? 37 THR A CG2 1 ATOM 238 N N . HIS A 1 32 ? -1.228 60.815 -27.419 1.00 21.67 ? 38 HIS A N 1 ATOM 239 C CA A HIS A 1 32 ? -2.166 60.523 -28.510 0.56 20.88 ? 38 HIS A CA 1 ATOM 240 C CA B HIS A 1 32 ? -1.963 60.386 -28.621 0.44 20.73 ? 38 HIS A CA 1 ATOM 241 C C . HIS A 1 32 ? -1.856 61.525 -29.623 1.00 20.74 ? 38 HIS A C 1 ATOM 242 O O . HIS A 1 32 ? -1.590 62.684 -29.306 1.00 20.97 ? 38 HIS A O 1 ATOM 243 C CB A HIS A 1 32 ? -3.642 60.765 -28.045 0.56 24.35 ? 38 HIS A CB 1 ATOM 244 C CB B HIS A 1 32 ? -3.450 60.035 -28.316 0.44 27.67 ? 38 HIS A CB 1 ATOM 245 C CG A HIS A 1 32 ? -3.984 60.181 -26.701 0.56 21.29 ? 38 HIS A CG 1 ATOM 246 C CG B HIS A 1 32 ? -4.115 59.075 -29.289 0.44 24.01 ? 38 HIS A CG 1 ATOM 247 N ND1 A HIS A 1 32 ? -4.320 60.950 -25.604 0.56 23.25 ? 38 HIS A ND1 1 ATOM 248 N ND1 B HIS A 1 32 ? -4.919 59.494 -30.330 0.44 23.70 ? 38 HIS A ND1 1 ATOM 249 C CD2 A HIS A 1 32 ? -4.135 58.885 -26.301 0.56 29.29 ? 38 HIS A CD2 1 ATOM 250 C CD2 B HIS A 1 32 ? -4.171 57.717 -29.313 0.44 33.02 ? 38 HIS A CD2 1 ATOM 251 C CE1 A HIS A 1 32 ? -4.574 60.162 -24.573 0.56 32.58 ? 38 HIS A CE1 1 ATOM 252 C CE1 B HIS A 1 32 ? -5.399 58.455 -30.981 0.44 23.18 ? 38 HIS A CE1 1 ATOM 253 N NE2 A HIS A 1 32 ? -4.438 58.905 -24.953 0.56 18.62 ? 38 HIS A NE2 1 ATOM 254 N NE2 B HIS A 1 32 ? -4.967 57.357 -30.379 0.44 28.33 ? 38 HIS A NE2 1 ATOM 255 N N . ALA A 1 33 ? -1.929 61.129 -30.894 1.00 17.49 ? 39 ALA A N 1 ATOM 256 C CA . ALA A 1 33 ? -1.784 62.108 -31.967 1.00 18.72 ? 39 ALA A CA 1 ATOM 257 C C . ALA A 1 33 ? -2.571 61.624 -33.160 1.00 24.14 ? 39 ALA A C 1 ATOM 258 O O . ALA A 1 33 ? -3.087 60.481 -33.142 1.00 22.11 ? 39 ALA A O 1 ATOM 259 C CB . ALA A 1 33 ? -0.323 62.284 -32.322 1.00 19.60 ? 39 ALA A CB 1 ATOM 260 N N A GLN A 1 34 ? -2.688 62.489 -34.170 0.49 18.42 ? 40 GLN A N 1 ATOM 261 N N B GLN A 1 34 ? -2.687 62.475 -34.182 0.51 18.42 ? 40 GLN A N 1 ATOM 262 C CA A GLN A 1 34 ? -3.455 62.163 -35.370 0.49 18.68 ? 40 GLN A CA 1 ATOM 263 C CA B GLN A 1 34 ? -3.474 62.126 -35.367 0.51 18.66 ? 40 GLN A CA 1 ATOM 264 C C A GLN A 1 34 ? -2.614 62.397 -36.631 0.49 22.33 ? 40 GLN A C 1 ATOM 265 C C B GLN A 1 34 ? -2.683 62.395 -36.651 0.51 22.35 ? 40 GLN A C 1 ATOM 266 O O A GLN A 1 34 ? -2.260 63.522 -36.957 0.49 19.69 ? 40 GLN A O 1 ATOM 267 O O B GLN A 1 34 ? -2.424 63.545 -37.003 0.51 19.70 ? 40 GLN A O 1 ATOM 268 C CB A GLN A 1 34 ? -4.773 62.953 -35.456 0.49 18.26 ? 40 GLN A CB 1 ATOM 269 C CB B GLN A 1 34 ? -4.832 62.851 -35.395 0.51 18.29 ? 40 GLN A CB 1 ATOM 270 C CG A GLN A 1 34 ? -5.613 62.577 -36.678 0.49 18.18 ? 40 GLN A CG 1 ATOM 271 C CG B GLN A 1 34 ? -5.760 62.444 -34.256 0.51 14.49 ? 40 GLN A CG 1 ATOM 272 C CD A GLN A 1 34 ? -6.003 61.092 -36.713 0.49 25.92 ? 40 GLN A CD 1 ATOM 273 C CD B GLN A 1 34 ? -6.448 61.099 -34.447 0.51 27.87 ? 40 GLN A CD 1 ATOM 274 O OE1 A GLN A 1 34 ? -6.722 60.665 -35.797 0.49 25.93 ? 40 GLN A OE1 1 ATOM 275 O OE1 B GLN A 1 34 ? -6.270 60.434 -35.459 0.51 25.77 ? 40 GLN A OE1 1 ATOM 276 N NE2 A GLN A 1 34 ? -5.517 60.284 -37.751 0.49 19.98 ? 40 GLN A NE2 1 ATOM 277 N NE2 B GLN A 1 34 ? -7.254 60.704 -33.449 0.51 22.73 ? 40 GLN A NE2 1 ATOM 278 N N . ASP A 1 35 ? -2.306 61.321 -37.347 1.00 19.43 ? 41 ASP A N 1 ATOM 279 C CA . ASP A 1 35 ? -1.664 61.478 -38.665 1.00 21.14 ? 41 ASP A CA 1 ATOM 280 C C . ASP A 1 35 ? -2.730 62.065 -39.627 1.00 23.44 ? 41 ASP A C 1 ATOM 281 O O . ASP A 1 35 ? -3.881 61.640 -39.602 1.00 21.43 ? 41 ASP A O 1 ATOM 282 C CB . ASP A 1 35 ? -1.278 60.072 -39.175 1.00 22.99 ? 41 ASP A CB 1 ATOM 283 C CG . ASP A 1 35 ? -0.412 60.105 -40.451 1.00 27.27 ? 41 ASP A CG 1 ATOM 284 O OD1 . ASP A 1 35 ? -0.259 61.171 -41.090 1.00 22.29 ? 41 ASP A OD1 1 ATOM 285 O OD2 . ASP A 1 35 ? 0.129 59.029 -40.787 1.00 27.76 ? 41 ASP A OD2 1 ATOM 286 N N . ILE A 1 36 ? -2.363 63.055 -40.470 1.00 17.78 ? 42 ILE A N 1 ATOM 287 C CA . ILE A 1 36 ? -3.358 63.650 -41.382 1.00 16.20 ? 42 ILE A CA 1 ATOM 288 C C . ILE A 1 36 ? -2.896 63.565 -42.828 1.00 18.37 ? 42 ILE A C 1 ATOM 289 O O . ILE A 1 36 ? -3.527 64.168 -43.682 1.00 18.60 ? 42 ILE A O 1 ATOM 290 C CB . ILE A 1 36 ? -3.707 65.089 -41.049 1.00 18.79 ? 42 ILE A CB 1 ATOM 291 C CG1 . ILE A 1 36 ? -2.466 66.013 -41.087 1.00 19.23 ? 42 ILE A CG1 1 ATOM 292 C CG2 . ILE A 1 36 ? -4.292 65.108 -39.628 1.00 19.06 ? 42 ILE A CG2 1 ATOM 293 C CD1 . ILE A 1 36 ? -2.912 67.582 -40.926 1.00 20.79 ? 42 ILE A CD1 1 ATOM 294 N N . LEU A 1 37 ? -1.866 62.773 -43.076 1.00 20.42 ? 43 LEU A N 1 ATOM 295 C CA . LEU A 1 37 ? -1.273 62.682 -44.445 1.00 17.28 ? 43 LEU A CA 1 ATOM 296 C C . LEU A 1 37 ? -1.333 61.242 -45.003 1.00 22.29 ? 43 LEU A C 1 ATOM 297 O O . LEU A 1 37 ? -0.768 60.330 -44.423 1.00 21.95 ? 43 LEU A O 1 ATOM 298 C CB . LEU A 1 37 ? 0.184 63.083 -44.370 1.00 19.27 ? 43 LEU A CB 1 ATOM 299 C CG . LEU A 1 37 ? 0.943 63.043 -45.732 1.00 20.50 ? 43 LEU A CG 1 ATOM 300 C CD1 . LEU A 1 37 ? 0.422 64.055 -46.708 1.00 22.79 ? 43 LEU A CD1 1 ATOM 301 C CD2 . LEU A 1 37 ? 2.486 63.251 -45.473 1.00 22.18 ? 43 LEU A CD2 1 ATOM 302 N N . GLU A 1 38 ? -2.020 61.069 -46.123 1.00 19.43 ? 44 GLU A N 1 ATOM 303 C CA . GLU A 1 38 ? -2.089 59.740 -46.776 1.00 20.03 ? 44 GLU A CA 1 ATOM 304 C C . GLU A 1 38 ? -0.835 59.563 -47.604 1.00 23.79 ? 44 GLU A C 1 ATOM 305 O O . GLU A 1 38 ? -0.548 60.398 -48.455 1.00 20.25 ? 44 GLU A O 1 ATOM 306 C CB . GLU A 1 38 ? -3.345 59.658 -47.655 1.00 20.01 ? 44 GLU A CB 1 ATOM 307 C CG . GLU A 1 38 ? -3.428 58.296 -48.403 1.00 22.55 ? 44 GLU A CG 1 ATOM 308 C CD . GLU A 1 38 ? -3.486 57.140 -47.366 1.00 24.95 ? 44 GLU A CD 1 ATOM 309 O OE1 . GLU A 1 38 ? -2.550 56.337 -47.348 1.00 25.42 ? 44 GLU A OE1 1 ATOM 310 O OE2 . GLU A 1 38 ? -4.455 57.126 -46.588 1.00 29.10 ? 44 GLU A OE2 1 ATOM 311 N N . LYS A 1 39 ? -0.105 58.466 -47.380 1.00 20.37 ? 45 LYS A N 1 ATOM 312 C CA . LYS A 1 39 ? 1.119 58.219 -48.089 1.00 26.12 ? 45 LYS A CA 1 ATOM 313 C C . LYS A 1 39 ? 1.021 56.962 -48.947 1.00 22.95 ? 45 LYS A C 1 ATOM 314 O O . LYS A 1 39 ? 2.007 56.623 -49.574 1.00 27.42 ? 45 LYS A O 1 ATOM 315 C CB . LYS A 1 39 ? 2.268 58.052 -47.077 1.00 26.64 ? 45 LYS A CB 1 ATOM 316 C CG . LYS A 1 39 ? 2.427 59.339 -46.203 1.00 27.75 ? 45 LYS A CG 1 ATOM 317 C CD . LYS A 1 39 ? 3.349 59.201 -44.942 1.00 31.27 ? 45 LYS A CD 1 ATOM 318 C CE . LYS A 1 39 ? 2.576 58.619 -43.692 1.00 33.01 ? 45 LYS A CE 1 ATOM 319 N NZ . LYS A 1 39 ? 1.401 59.389 -43.034 1.00 26.01 ? 45 LYS A NZ 1 ATOM 320 N N . LYS A 1 40 ? -0.109 56.272 -48.927 1.00 21.54 ? 46 LYS A N 1 ATOM 321 C CA . LYS A 1 40 ? -0.194 55.005 -49.699 1.00 23.06 ? 46 LYS A CA 1 ATOM 322 C C . LYS A 1 40 ? -1.102 55.094 -50.886 1.00 26.14 ? 46 LYS A C 1 ATOM 323 O O . LYS A 1 40 ? -2.101 55.831 -50.858 1.00 25.80 ? 46 LYS A O 1 ATOM 324 C CB . LYS A 1 40 ? -0.779 53.921 -48.788 1.00 28.15 ? 46 LYS A CB 1 ATOM 325 C CG . LYS A 1 40 ? 0.039 53.739 -47.495 1.00 33.66 ? 46 LYS A CG 1 ATOM 326 C CD . LYS A 1 40 ? -0.623 52.669 -46.554 1.00 41.07 ? 46 LYS A CD 1 ATOM 327 C CE . LYS A 1 40 ? -2.101 52.972 -46.261 1.00 48.26 ? 46 LYS A CE 1 ATOM 328 N NZ . LYS A 1 40 ? -2.461 54.330 -45.624 1.00 41.35 ? 46 LYS A NZ 1 ATOM 329 N N . HIS A 1 41 ? -0.818 54.262 -51.901 1.00 25.88 ? 47 HIS A N 1 ATOM 330 C CA . HIS A 1 41 ? -1.739 54.147 -53.036 1.00 21.10 ? 47 HIS A CA 1 ATOM 331 C C . HIS A 1 41 ? -1.650 52.702 -53.514 1.00 29.68 ? 47 HIS A C 1 ATOM 332 O O . HIS A 1 41 ? -0.725 51.997 -53.081 1.00 27.83 ? 47 HIS A O 1 ATOM 333 C CB . HIS A 1 41 ? -1.279 55.088 -54.180 1.00 23.15 ? 47 HIS A CB 1 ATOM 334 C CG . HIS A 1 41 ? 0.080 54.791 -54.716 1.00 25.57 ? 47 HIS A CG 1 ATOM 335 N ND1 . HIS A 1 41 ? 0.323 53.788 -55.643 1.00 24.68 ? 47 HIS A ND1 1 ATOM 336 C CD2 . HIS A 1 41 ? 1.281 55.361 -54.462 1.00 30.73 ? 47 HIS A CD2 1 ATOM 337 C CE1 . HIS A 1 41 ? 1.610 53.786 -55.946 1.00 29.60 ? 47 HIS A CE1 1 ATOM 338 N NE2 . HIS A 1 41 ? 2.219 54.716 -55.226 1.00 29.07 ? 47 HIS A NE2 1 ATOM 339 N N . ASN A 1 42 ? -2.544 52.283 -54.411 1.00 26.54 ? 48 ASN A N 1 ATOM 340 C CA . ASN A 1 42 ? -2.571 50.838 -54.808 1.00 27.25 ? 48 ASN A CA 1 ATOM 341 C C . ASN A 1 42 ? -1.768 50.497 -56.073 1.00 30.76 ? 48 ASN A C 1 ATOM 342 O O . ASN A 1 42 ? -1.724 49.315 -56.496 1.00 30.17 ? 48 ASN A O 1 ATOM 343 C CB . ASN A 1 42 ? -4.011 50.294 -54.890 1.00 29.22 ? 48 ASN A CB 1 ATOM 344 C CG . ASN A 1 42 ? -4.786 50.803 -56.138 1.00 30.35 ? 48 ASN A CG 1 ATOM 345 O OD1 . ASN A 1 42 ? -4.262 51.570 -56.932 1.00 27.46 ? 48 ASN A OD1 1 ATOM 346 N ND2 . ASN A 1 42 ? -6.041 50.381 -56.278 1.00 33.09 ? 48 ASN A ND2 1 ATOM 347 N N . GLY A 1 43 ? -1.120 51.491 -56.685 1.00 26.76 ? 49 GLY A N 1 ATOM 348 C CA . GLY A 1 43 ? -0.272 51.225 -57.826 1.00 28.11 ? 49 GLY A CA 1 ATOM 349 C C . GLY A 1 43 ? -1.018 50.797 -59.096 1.00 26.93 ? 49 GLY A C 1 ATOM 350 O O . GLY A 1 43 ? -0.374 50.346 -60.063 1.00 31.50 ? 49 GLY A O 1 ATOM 351 N N . LYS A 1 44 ? -2.316 50.971 -59.135 1.00 24.94 ? 50 LYS A N 1 ATOM 352 C CA . LYS A 1 44 ? -3.075 50.534 -60.325 1.00 27.50 ? 50 LYS A CA 1 ATOM 353 C C . LYS A 1 44 ? -3.887 51.678 -60.887 1.00 34.59 ? 50 LYS A C 1 ATOM 354 O O . LYS A 1 44 ? -4.226 52.625 -60.184 1.00 27.40 ? 50 LYS A O 1 ATOM 355 C CB . LYS A 1 44 ? -3.988 49.357 -59.980 1.00 20.00 ? 50 LYS A CB 1 ATOM 356 C CG . LYS A 1 44 ? -3.246 48.076 -59.631 1.00 20.00 ? 50 LYS A CG 1 ATOM 357 C CD . LYS A 1 44 ? -4.210 46.957 -59.276 1.00 20.00 ? 50 LYS A CD 1 ATOM 358 C CE . LYS A 1 44 ? -3.470 45.670 -58.951 1.00 20.00 ? 50 LYS A CE 1 ATOM 359 N NZ . LYS A 1 44 ? -4.402 44.572 -58.577 1.00 20.00 ? 50 LYS A NZ 1 ATOM 360 N N . LEU A 1 45 ? -4.275 51.547 -62.146 1.00 25.88 ? 51 LEU A N 1 ATOM 361 C CA . LEU A 1 45 ? -5.262 52.439 -62.742 1.00 24.43 ? 51 LEU A CA 1 ATOM 362 C C . LEU A 1 45 ? -6.652 51.844 -62.669 1.00 32.60 ? 51 LEU A C 1 ATOM 363 O O . LEU A 1 45 ? -6.893 50.735 -63.187 1.00 33.18 ? 51 LEU A O 1 ATOM 364 C CB . LEU A 1 45 ? -4.903 52.732 -64.207 1.00 26.73 ? 51 LEU A CB 1 ATOM 365 C CG . LEU A 1 45 ? -3.515 53.329 -64.485 1.00 30.88 ? 51 LEU A CG 1 ATOM 366 C CD1 . LEU A 1 45 ? -3.262 53.578 -65.991 1.00 28.51 ? 51 LEU A CD1 1 ATOM 367 C CD2 . LEU A 1 45 ? -3.280 54.601 -63.650 1.00 33.67 ? 51 LEU A CD2 1 ATOM 368 N N . CYS A 1 46 ? -7.572 52.537 -62.029 1.00 26.15 ? 52 CYS A N 1 ATOM 369 C CA . CYS A 1 46 ? -8.895 51.954 -61.706 1.00 27.72 ? 52 CYS A CA 1 ATOM 370 C C . CYS A 1 46 ? -10.074 52.623 -62.395 1.00 26.92 ? 52 CYS A C 1 ATOM 371 O O . CYS A 1 46 ? -9.934 53.740 -62.947 1.00 28.71 ? 52 CYS A O 1 ATOM 372 C CB . CYS A 1 46 ? -9.142 51.995 -60.171 1.00 29.23 ? 52 CYS A CB 1 ATOM 373 S SG . CYS A 1 46 ? -7.825 51.169 -59.247 1.00 33.13 ? 52 CYS A SG 1 ATOM 374 N N . ASP A 1 47 ? -11.251 51.978 -62.347 1.00 27.13 ? 53 ASP A N 1 ATOM 375 C CA . ASP A 1 47 ? -12.484 52.652 -62.670 1.00 25.64 ? 53 ASP A CA 1 ATOM 376 C C . ASP A 1 47 ? -12.657 53.801 -61.691 1.00 28.62 ? 53 ASP A C 1 ATOM 377 O O . ASP A 1 47 ? -12.184 53.707 -60.589 1.00 26.77 ? 53 ASP A O 1 ATOM 378 C CB . ASP A 1 47 ? -13.731 51.730 -62.545 1.00 29.60 ? 53 ASP A CB 1 ATOM 379 C CG . ASP A 1 47 ? -13.668 50.493 -63.469 1.00 37.40 ? 53 ASP A CG 1 ATOM 380 O OD1 . ASP A 1 47 ? -12.822 50.412 -64.375 1.00 29.40 ? 53 ASP A OD1 1 ATOM 381 O OD2 . ASP A 1 47 ? -14.480 49.561 -63.240 1.00 36.90 ? 53 ASP A OD2 1 ATOM 382 N N . LEU A 1 48 ? -13.254 54.887 -62.150 1.00 27.77 ? 54 LEU A N 1 ATOM 383 C CA . LEU A 1 48 ? -13.554 56.030 -61.308 1.00 25.60 ? 54 LEU A CA 1 ATOM 384 C C . LEU A 1 48 ? -15.062 56.003 -61.067 1.00 30.19 ? 54 LEU A C 1 ATOM 385 O O . LEU A 1 48 ? -15.870 56.307 -61.980 1.00 31.06 ? 54 LEU A O 1 ATOM 386 C CB . LEU A 1 48 ? -13.132 57.346 -61.981 1.00 24.64 ? 54 LEU A CB 1 ATOM 387 C CG . LEU A 1 48 ? -13.246 58.615 -61.106 1.00 28.14 ? 54 LEU A CG 1 ATOM 388 C CD1 . LEU A 1 48 ? -12.258 58.553 -59.954 1.00 28.76 ? 54 LEU A CD1 1 ATOM 389 C CD2 . LEU A 1 48 ? -12.915 59.821 -61.923 1.00 29.23 ? 54 LEU A CD2 1 ATOM 390 N N . ASP A 1 49 ? -15.422 55.657 -59.829 1.00 31.28 ? 55 ASP A N 1 ATOM 391 C CA A ASP A 1 49 ? -16.837 55.546 -59.400 0.55 31.31 ? 55 ASP A CA 1 ATOM 392 C CA B ASP A 1 49 ? -16.829 55.546 -59.415 0.45 31.34 ? 55 ASP A CA 1 ATOM 393 C C . ASP A 1 49 ? -17.610 54.679 -60.401 1.00 31.40 ? 55 ASP A C 1 ATOM 394 O O . ASP A 1 49 ? -18.688 55.057 -60.857 1.00 35.41 ? 55 ASP A O 1 ATOM 395 C CB A ASP A 1 49 ? -17.501 56.919 -59.281 0.55 32.79 ? 55 ASP A CB 1 ATOM 396 C CB B ASP A 1 49 ? -17.474 56.918 -59.320 0.45 32.81 ? 55 ASP A CB 1 ATOM 397 C CG A ASP A 1 49 ? -18.660 56.947 -58.266 0.55 39.57 ? 55 ASP A CG 1 ATOM 398 C CG B ASP A 1 49 ? -16.737 57.837 -58.372 0.45 30.93 ? 55 ASP A CG 1 ATOM 399 O OD1 A ASP A 1 49 ? -18.852 55.982 -57.487 0.55 39.56 ? 55 ASP A OD1 1 ATOM 400 O OD1 B ASP A 1 49 ? -16.308 57.367 -57.284 0.45 34.21 ? 55 ASP A OD1 1 ATOM 401 O OD2 A ASP A 1 49 ? -19.376 57.972 -58.238 0.55 45.29 ? 55 ASP A OD2 1 ATOM 402 O OD2 B ASP A 1 49 ? -16.587 59.026 -58.724 0.45 36.78 ? 55 ASP A OD2 1 ATOM 403 N N . GLY A 1 50 A -17.026 53.558 -60.756 1.00 32.29 ? 55 GLY A N 1 ATOM 404 C CA . GLY A 1 50 A -17.714 52.578 -61.579 1.00 38.19 ? 55 GLY A CA 1 ATOM 405 C C . GLY A 1 50 A -17.546 52.759 -63.077 1.00 38.53 ? 55 GLY A C 1 ATOM 406 O O . GLY A 1 50 A -18.041 51.940 -63.844 1.00 35.12 ? 55 GLY A O 1 ATOM 407 N N . VAL A 1 51 ? -16.894 53.837 -63.511 1.00 32.70 ? 56 VAL A N 1 ATOM 408 C CA . VAL A 1 51 ? -16.716 54.090 -64.944 1.00 28.20 ? 56 VAL A CA 1 ATOM 409 C C . VAL A 1 51 ? -15.275 53.873 -65.396 1.00 31.43 ? 56 VAL A C 1 ATOM 410 O O . VAL A 1 51 ? -14.340 54.510 -64.875 1.00 27.32 ? 56 VAL A O 1 ATOM 411 C CB . VAL A 1 51 ? -17.107 55.534 -65.284 1.00 28.52 ? 56 VAL A CB 1 ATOM 412 C CG1 . VAL A 1 51 ? -16.951 55.772 -66.807 1.00 30.62 ? 56 VAL A CG1 1 ATOM 413 C CG2 . VAL A 1 51 ? -18.524 55.801 -64.856 1.00 39.24 ? 56 VAL A CG2 1 ATOM 414 N N . LYS A 1 52 ? -15.063 52.989 -66.372 1.00 28.23 ? 57 LYS A N 1 ATOM 415 C CA . LYS A 1 52 ? -13.716 52.590 -66.720 1.00 23.92 ? 57 LYS A CA 1 ATOM 416 C C . LYS A 1 52 ? -13.020 53.666 -67.510 1.00 24.81 ? 57 LYS A C 1 ATOM 417 O O . LYS A 1 52 ? -13.628 54.316 -68.352 1.00 27.68 ? 57 LYS A O 1 ATOM 418 C CB . LYS A 1 52 ? -13.701 51.231 -67.504 1.00 30.71 ? 57 LYS A CB 1 ATOM 419 C CG . LYS A 1 52 ? -12.299 50.745 -67.850 1.00 30.72 ? 57 LYS A CG 1 ATOM 420 C CD . LYS A 1 52 ? -12.287 49.414 -68.664 1.00 35.92 ? 57 LYS A CD 1 ATOM 421 C CE . LYS A 1 52 ? -10.866 49.068 -69.160 1.00 40.77 ? 57 LYS A CE 1 ATOM 422 N NZ . LYS A 1 52 ? -10.521 49.973 -70.319 1.00 49.11 ? 57 LYS A NZ 1 ATOM 423 N N . PRO A 1 53 ? -11.736 53.886 -67.261 1.00 23.76 ? 58 PRO A N 1 ATOM 424 C CA . PRO A 1 53 ? -11.012 54.817 -68.130 1.00 24.15 ? 58 PRO A CA 1 ATOM 425 C C . PRO A 1 53 ? -10.796 54.288 -69.552 1.00 28.98 ? 58 PRO A C 1 ATOM 426 O O . PRO A 1 53 ? -10.819 53.090 -69.766 1.00 26.12 ? 58 PRO A O 1 ATOM 427 C CB . PRO A 1 53 ? -9.630 54.879 -67.456 1.00 24.29 ? 58 PRO A CB 1 ATOM 428 C CG . PRO A 1 53 ? -9.526 53.568 -66.701 1.00 26.56 ? 58 PRO A CG 1 ATOM 429 C CD . PRO A 1 53 ? -10.882 53.376 -66.167 1.00 25.05 ? 58 PRO A CD 1 ATOM 430 N N . LEU A 1 54 ? -10.553 55.196 -70.481 1.00 24.61 ? 59 LEU A N 1 ATOM 431 C CA . LEU A 1 54 ? -10.061 54.834 -71.810 1.00 24.02 ? 59 LEU A CA 1 ATOM 432 C C . LEU A 1 54 ? -8.542 54.758 -71.696 1.00 28.96 ? 59 LEU A C 1 ATOM 433 O O . LEU A 1 54 ? -7.878 55.770 -71.447 1.00 25.06 ? 59 LEU A O 1 ATOM 434 C CB . LEU A 1 54 ? -10.467 55.909 -72.800 1.00 22.91 ? 59 LEU A CB 1 ATOM 435 C CG . LEU A 1 54 ? -9.811 55.817 -74.199 1.00 24.19 ? 59 LEU A CG 1 ATOM 436 C CD1 . LEU A 1 54 ? -10.101 54.413 -74.878 1.00 26.99 ? 59 LEU A CD1 1 ATOM 437 C CD2 . LEU A 1 54 ? -10.293 56.950 -75.099 1.00 21.56 ? 59 LEU A CD2 1 ATOM 438 N N . ILE A 1 55 ? -7.990 53.561 -71.807 1.00 21.51 ? 60 ILE A N 1 ATOM 439 C CA . ILE A 1 55 ? -6.539 53.397 -71.680 1.00 24.71 ? 60 ILE A CA 1 ATOM 440 C C . ILE A 1 55 ? -5.996 53.146 -73.068 1.00 29.09 ? 60 ILE A C 1 ATOM 441 O O . ILE A 1 55 ? -6.301 52.107 -73.686 1.00 27.68 ? 60 ILE A O 1 ATOM 442 C CB . ILE A 1 55 ? -6.193 52.244 -70.719 1.00 26.95 ? 60 ILE A CB 1 ATOM 443 C CG1 . ILE A 1 55 ? -6.640 52.634 -69.300 1.00 32.89 ? 60 ILE A CG1 1 ATOM 444 C CG2 . ILE A 1 55 ? -4.697 51.948 -70.740 1.00 27.35 ? 60 ILE A CG2 1 ATOM 445 C CD1 . ILE A 1 55 ? -6.775 51.458 -68.382 1.00 40.99 ? 60 ILE A CD1 1 ATOM 446 N N . LEU A 1 56 ? -5.290 54.124 -73.616 1.00 21.98 ? 61 LEU A N 1 ATOM 447 C CA . LEU A 1 56 ? -4.868 54.042 -75.002 1.00 22.83 ? 61 LEU A CA 1 ATOM 448 C C . LEU A 1 56 ? -3.697 53.081 -75.292 1.00 31.15 ? 61 LEU A C 1 ATOM 449 O O . LEU A 1 56 ? -3.360 52.884 -76.461 1.00 24.73 ? 61 LEU A O 1 ATOM 450 C CB . LEU A 1 56 ? -4.561 55.444 -75.576 1.00 22.24 ? 61 LEU A CB 1 ATOM 451 C CG . LEU A 1 56 ? -5.795 56.364 -75.696 1.00 25.54 ? 61 LEU A CG 1 ATOM 452 C CD1 . LEU A 1 56 ? -5.372 57.796 -76.040 1.00 26.37 ? 61 LEU A CD1 1 ATOM 453 C CD2 . LEU A 1 56 ? -6.840 55.794 -76.729 1.00 26.12 ? 61 LEU A CD2 1 ATOM 454 N N . ARG A 1 57 ? -3.085 52.494 -74.255 1.00 29.16 ? 62 ARG A N 1 ATOM 455 C CA . ARG A 1 57 ? -1.992 51.524 -74.508 1.00 31.70 ? 62 ARG A CA 1 ATOM 456 C C . ARG A 1 57 ? -0.871 52.116 -75.348 1.00 33.77 ? 62 ARG A C 1 ATOM 457 O O . ARG A 1 57 ? -0.265 53.090 -74.906 1.00 34.11 ? 62 ARG A O 1 ATOM 458 C CB . ARG A 1 57 ? -2.532 50.213 -75.086 1.00 31.68 ? 62 ARG A CB 1 ATOM 459 C CG . ARG A 1 57 ? -3.627 49.700 -74.219 1.00 36.80 ? 62 ARG A CG 1 ATOM 460 C CD . ARG A 1 57 ? -4.105 48.350 -74.658 1.00 50.96 ? 62 ARG A CD 1 ATOM 461 N NE . ARG A 1 57 ? -2.986 47.443 -74.850 1.00 43.49 ? 62 ARG A NE 1 ATOM 462 C CZ . ARG A 1 57 ? -3.149 46.182 -75.211 1.00 63.92 ? 62 ARG A CZ 1 ATOM 463 N NH1 . ARG A 1 57 ? -4.377 45.735 -75.430 1.00 49.96 ? 62 ARG A NH1 1 ATOM 464 N NH2 . ARG A 1 57 ? -2.096 45.377 -75.360 1.00 58.46 ? 62 ARG A NH2 1 ATOM 465 N N . ASP A 1 58 ? -0.587 51.599 -76.557 1.00 24.23 ? 63 ASP A N 1 ATOM 466 C CA . ASP A 1 58 ? 0.513 52.184 -77.333 1.00 30.09 ? 63 ASP A CA 1 ATOM 467 C C . ASP A 1 58 ? 0.101 53.212 -78.363 1.00 25.35 ? 63 ASP A C 1 ATOM 468 O O . ASP A 1 58 ? 0.920 53.633 -79.211 1.00 29.75 ? 63 ASP A O 1 ATOM 469 C CB . ASP A 1 58 ? 1.329 51.083 -78.006 1.00 30.51 ? 63 ASP A CB 1 ATOM 470 C CG . ASP A 1 58 ? 2.017 50.211 -76.972 1.00 48.62 ? 63 ASP A CG 1 ATOM 471 O OD1 . ASP A 1 58 ? 2.789 50.766 -76.148 1.00 37.36 ? 63 ASP A OD1 1 ATOM 472 O OD2 . ASP A 1 58 ? 1.722 48.994 -76.928 1.00 43.25 ? 63 ASP A OD2 1 ATOM 473 N N . CYS A 1 59 ? -1.160 53.637 -78.258 1.00 28.78 ? 64 CYS A N 1 ATOM 474 C CA . CYS A 1 59 ? -1.722 54.605 -79.180 1.00 24.28 ? 64 CYS A CA 1 ATOM 475 C C . CYS A 1 59 ? -1.781 56.022 -78.588 1.00 25.08 ? 64 CYS A C 1 ATOM 476 O O . CYS A 1 59 ? -2.065 56.161 -77.412 1.00 27.13 ? 64 CYS A O 1 ATOM 477 C CB . CYS A 1 59 ? -3.146 54.205 -79.509 1.00 27.79 ? 64 CYS A CB 1 ATOM 478 S SG . CYS A 1 59 ? -3.034 52.793 -80.744 1.00 40.25 ? 64 CYS A SG 1 ATOM 479 N N . SER A 1 60 ? -1.549 57.012 -79.437 1.00 25.59 ? 65 SER A N 1 ATOM 480 C CA . SER A 1 60 ? -1.765 58.417 -79.068 1.00 22.66 ? 65 SER A CA 1 ATOM 481 C C . SER A 1 60 ? -3.196 58.841 -79.306 1.00 24.87 ? 65 SER A C 1 ATOM 482 O O . SER A 1 60 ? -3.981 58.200 -80.014 1.00 23.25 ? 65 SER A O 1 ATOM 483 C CB . SER A 1 60 ? -0.856 59.350 -79.865 1.00 24.93 ? 65 SER A CB 1 ATOM 484 O OG . SER A 1 60 ? -1.217 59.387 -81.254 1.00 25.89 ? 65 SER A OG 1 ATOM 485 N N . VAL A 1 61 ? -3.576 59.970 -78.735 1.00 20.27 ? 66 VAL A N 1 ATOM 486 C CA . VAL A 1 61 ? -4.874 60.526 -79.141 1.00 21.07 ? 66 VAL A CA 1 ATOM 487 C C . VAL A 1 61 ? -5.048 60.708 -80.667 1.00 20.92 ? 66 VAL A C 1 ATOM 488 O O . VAL A 1 61 ? -6.146 60.445 -81.207 1.00 23.08 ? 66 VAL A O 1 ATOM 489 C CB . VAL A 1 61 ? -5.099 61.885 -78.433 1.00 21.87 ? 66 VAL A CB 1 ATOM 490 C CG1 . VAL A 1 61 ? -6.378 62.558 -78.964 1.00 21.83 ? 66 VAL A CG1 1 ATOM 491 C CG2 . VAL A 1 61 ? -5.169 61.599 -76.976 1.00 24.24 ? 66 VAL A CG2 1 ATOM 492 N N . ALA A 1 62 ? -4.014 61.197 -81.356 1.00 19.62 ? 67 ALA A N 1 ATOM 493 C CA . ALA A 1 62 ? -4.055 61.385 -82.802 1.00 22.65 ? 67 ALA A CA 1 ATOM 494 C C . ALA A 1 62 ? -4.272 59.985 -83.474 1.00 21.32 ? 67 ALA A C 1 ATOM 495 O O . ALA A 1 62 ? -5.125 59.839 -84.389 1.00 23.07 ? 67 ALA A O 1 ATOM 496 C CB . ALA A 1 62 ? -2.798 61.994 -83.277 1.00 21.04 ? 67 ALA A CB 1 ATOM 497 N N . GLY A 1 63 ? -3.548 58.992 -82.984 1.00 24.11 ? 68 GLY A N 1 ATOM 498 C CA . GLY A 1 63 ? -3.676 57.648 -83.553 1.00 25.15 ? 68 GLY A CA 1 ATOM 499 C C . GLY A 1 63 ? -5.069 57.085 -83.404 1.00 23.18 ? 68 GLY A C 1 ATOM 500 O O . GLY A 1 63 ? -5.656 56.459 -84.363 1.00 24.48 ? 68 GLY A O 1 ATOM 501 N N . TRP A 1 64 ? -5.641 57.287 -82.218 1.00 20.96 ? 69 TRP A N 1 ATOM 502 C CA . TRP A 1 64 ? -7.028 56.917 -81.970 1.00 22.12 ? 69 TRP A CA 1 ATOM 503 C C . TRP A 1 64 ? -7.995 57.651 -82.886 1.00 26.78 ? 69 TRP A C 1 ATOM 504 O O . TRP A 1 64 ? -8.786 57.003 -83.624 1.00 22.69 ? 69 TRP A O 1 ATOM 505 C CB . TRP A 1 64 ? -7.340 57.242 -80.496 1.00 22.84 ? 69 TRP A CB 1 ATOM 506 C CG . TRP A 1 64 ? -8.788 57.248 -80.140 1.00 21.17 ? 69 TRP A CG 1 ATOM 507 C CD1 . TRP A 1 64 ? -9.817 56.490 -80.690 1.00 23.28 ? 69 TRP A CD1 1 ATOM 508 C CD2 . TRP A 1 64 ? -9.404 58.104 -79.173 1.00 22.40 ? 69 TRP A CD2 1 ATOM 509 N NE1 . TRP A 1 64 ? -10.999 56.799 -80.084 1.00 24.93 ? 69 TRP A NE1 1 ATOM 510 C CE2 . TRP A 1 64 ? -10.779 57.781 -79.143 1.00 21.49 ? 69 TRP A CE2 1 ATOM 511 C CE3 . TRP A 1 64 ? -8.910 59.088 -78.287 1.00 23.55 ? 69 TRP A CE3 1 ATOM 512 C CZ2 . TRP A 1 64 ? -11.680 58.420 -78.275 1.00 24.01 ? 69 TRP A CZ2 1 ATOM 513 C CZ3 . TRP A 1 64 ? -9.820 59.728 -77.451 1.00 21.96 ? 69 TRP A CZ3 1 ATOM 514 C CH2 . TRP A 1 64 ? -11.157 59.400 -77.455 1.00 26.30 ? 69 TRP A CH2 1 ATOM 515 N N . LEU A 1 65 ? -7.974 58.998 -82.864 1.00 20.90 ? 70 LEU A N 1 ATOM 516 C CA . LEU A 1 65 ? -9.032 59.719 -83.570 1.00 19.21 ? 70 LEU A CA 1 ATOM 517 C C . LEU A 1 65 ? -8.913 59.666 -85.104 1.00 19.75 ? 70 LEU A C 1 ATOM 518 O O . LEU A 1 65 ? -9.935 59.712 -85.793 1.00 24.91 ? 70 LEU A O 1 ATOM 519 C CB . LEU A 1 65 ? -9.090 61.192 -83.145 1.00 19.34 ? 70 LEU A CB 1 ATOM 520 C CG . LEU A 1 65 ? -9.420 61.291 -81.666 1.00 20.75 ? 70 LEU A CG 1 ATOM 521 C CD1 . LEU A 1 65 ? -9.414 62.829 -81.288 1.00 22.42 ? 70 LEU A CD1 1 ATOM 522 C CD2 . LEU A 1 65 ? -10.765 60.646 -81.260 1.00 21.27 ? 70 LEU A CD2 1 ATOM 523 N N . LEU A 1 66 ? -7.696 59.625 -85.643 1.00 20.77 ? 71 LEU A N 1 ATOM 524 C CA . LEU A 1 66 ? -7.585 59.532 -87.095 1.00 22.93 ? 71 LEU A CA 1 ATOM 525 C C . LEU A 1 66 ? -7.755 58.059 -87.525 1.00 24.88 ? 71 LEU A C 1 ATOM 526 O O . LEU A 1 66 ? -7.975 57.770 -88.717 1.00 22.48 ? 71 LEU A O 1 ATOM 527 C CB . LEU A 1 66 ? -6.200 59.977 -87.565 1.00 22.47 ? 71 LEU A CB 1 ATOM 528 C CG . LEU A 1 66 ? -5.987 61.509 -87.417 1.00 25.69 ? 71 LEU A CG 1 ATOM 529 C CD1 . LEU A 1 66 ? -4.503 61.782 -87.567 1.00 24.08 ? 71 LEU A CD1 1 ATOM 530 C CD2 . LEU A 1 66 ? -6.742 62.279 -88.477 1.00 24.89 ? 71 LEU A CD2 1 ATOM 531 N N . GLY A 1 67 ? -7.549 57.147 -86.596 1.00 23.18 ? 72 GLY A N 1 ATOM 532 C CA . GLY A 1 67 ? -7.673 55.720 -86.882 1.00 26.19 ? 72 GLY A CA 1 ATOM 533 C C . GLY A 1 67 ? -6.448 55.053 -87.476 1.00 27.78 ? 72 GLY A C 1 ATOM 534 O O . GLY A 1 67 ? -6.544 54.310 -88.464 1.00 25.09 ? 72 GLY A O 1 ATOM 535 N N . ASN A 1 68 ? -5.276 55.295 -86.898 1.00 23.19 ? 73 ASN A N 1 ATOM 536 C CA . ASN A 1 68 ? -4.056 54.543 -87.234 1.00 28.75 ? 73 ASN A CA 1 ATOM 537 C C . ASN A 1 68 ? -4.422 53.060 -87.133 1.00 24.03 ? 73 ASN A C 1 ATOM 538 O O . ASN A 1 68 ? -5.072 52.611 -86.165 1.00 26.26 ? 73 ASN A O 1 ATOM 539 C CB . ASN A 1 68 ? -2.953 54.939 -86.229 1.00 29.92 ? 73 ASN A CB 1 ATOM 540 C CG . ASN A 1 68 ? -1.662 54.183 -86.415 1.00 33.50 ? 73 ASN A CG 1 ATOM 541 O OD1 . ASN A 1 68 ? -1.663 53.039 -86.838 1.00 28.32 ? 73 ASN A OD1 1 ATOM 542 N ND2 . ASN A 1 68 ? -0.530 54.824 -86.077 1.00 27.02 ? 73 ASN A ND2 1 ATOM 543 N N . PRO A 1 69 ? -4.084 52.285 -88.191 1.00 28.16 ? 74 PRO A N 1 ATOM 544 C CA . PRO A 1 69 ? -4.655 50.938 -88.190 1.00 27.92 ? 74 PRO A CA 1 ATOM 545 C C . PRO A 1 69 ? -4.057 50.030 -87.109 1.00 30.79 ? 74 PRO A C 1 ATOM 546 O O . PRO A 1 69 ? -4.645 49.000 -86.764 1.00 36.39 ? 74 PRO A O 1 ATOM 547 C CB . PRO A 1 69 ? -4.383 50.417 -89.636 1.00 29.73 ? 74 PRO A CB 1 ATOM 548 C CG . PRO A 1 69 ? -3.453 51.305 -90.269 1.00 30.03 ? 74 PRO A CG 1 ATOM 549 C CD . PRO A 1 69 ? -3.466 52.653 -89.468 1.00 25.94 ? 74 PRO A CD 1 ATOM 550 N N . MET A 1 70 ? -2.945 50.435 -86.518 1.00 24.64 ? 75 MET A N 1 ATOM 551 C CA . MET A 1 70 ? -2.430 49.741 -85.326 1.00 29.86 ? 75 MET A CA 1 ATOM 552 C C . MET A 1 70 ? -3.312 50.033 -84.097 1.00 33.38 ? 75 MET A C 1 ATOM 553 O O . MET A 1 70 ? -3.188 49.369 -83.078 1.00 31.79 ? 75 MET A O 1 ATOM 554 C CB . MET A 1 70 ? -0.979 50.150 -85.035 1.00 29.52 ? 75 MET A CB 1 ATOM 555 C CG . MET A 1 70 ? -0.010 50.019 -86.206 1.00 36.10 ? 75 MET A CG 1 ATOM 556 S SD . MET A 1 70 ? 0.011 48.256 -86.563 1.00 43.33 ? 75 MET A SD 1 ATOM 557 C CE . MET A 1 70 ? 0.619 47.611 -85.048 1.00 35.26 ? 75 MET A CE 1 ATOM 558 N N . CYS A 1 71 ? -4.228 51.005 -84.207 1.00 28.91 ? 76 CYS A N 1 ATOM 559 C CA . CYS A 1 71 ? -5.080 51.396 -83.070 1.00 30.51 ? 76 CYS A CA 1 ATOM 560 C C . CYS A 1 71 ? -6.467 50.800 -83.152 1.00 31.86 ? 76 CYS A C 1 ATOM 561 O O . CYS A 1 71 ? -7.420 51.357 -82.632 1.00 27.11 ? 76 CYS A O 1 ATOM 562 C CB . CYS A 1 71 ? -5.139 52.927 -82.921 1.00 29.89 ? 76 CYS A CB 1 ATOM 563 S SG . CYS A 1 71 ? -3.500 53.600 -82.706 1.00 30.36 ? 76 CYS A SG 1 ATOM 564 N N . ASP A 1 72 ? -6.595 49.605 -83.750 1.00 30.47 ? 77 ASP A N 1 ATOM 565 C CA . ASP A 1 72 ? -7.943 49.085 -83.986 1.00 32.02 ? 77 ASP A CA 1 ATOM 566 C C . ASP A 1 72 ? -8.666 48.687 -82.706 1.00 27.72 ? 77 ASP A C 1 ATOM 567 O O . ASP A 1 72 ? -9.883 48.527 -82.710 1.00 29.49 ? 77 ASP A O 1 ATOM 568 C CB . ASP A 1 72 ? -7.959 47.904 -84.982 1.00 36.72 ? 77 ASP A CB 1 ATOM 569 C CG . ASP A 1 72 ? -7.856 48.352 -86.466 1.00 43.04 ? 77 ASP A CG 1 ATOM 570 O OD1 . ASP A 1 72 ? -7.888 49.576 -86.785 1.00 33.18 ? 77 ASP A OD1 1 ATOM 571 O OD2 . ASP A 1 72 ? -7.805 47.453 -87.354 1.00 44.88 ? 77 ASP A OD2 1 ATOM 572 N N . GLU A 1 73 ? -7.952 48.569 -81.581 1.00 27.37 ? 78 GLU A N 1 ATOM 573 C CA . GLU A 1 73 ? -8.667 48.385 -80.319 1.00 27.24 ? 78 GLU A CA 1 ATOM 574 C C . GLU A 1 73 ? -9.690 49.520 -80.062 1.00 23.86 ? 78 GLU A C 1 ATOM 575 O O . GLU A 1 73 ? -10.666 49.352 -79.344 1.00 26.37 ? 78 GLU A O 1 ATOM 576 C CB . GLU A 1 73 ? -7.646 48.355 -79.154 1.00 28.70 ? 78 GLU A CB 1 ATOM 577 C CG . GLU A 1 73 ? -8.279 48.098 -77.821 1.00 28.96 ? 78 GLU A CG 1 ATOM 578 C CD . GLU A 1 73 ? -7.251 47.868 -76.689 1.00 34.89 ? 78 GLU A CD 1 ATOM 579 O OE1 . GLU A 1 73 ? -7.678 47.834 -75.517 1.00 36.35 ? 78 GLU A OE1 1 ATOM 580 O OE2 . GLU A 1 73 ? -6.028 47.711 -76.983 1.00 35.54 ? 78 GLU A OE2 1 ATOM 581 N N . PHE A 1 74 ? -9.429 50.672 -80.672 1.00 24.88 ? 79 PHE A N 1 ATOM 582 C CA . PHE A 1 74 ? -10.171 51.889 -80.337 1.00 25.89 ? 79 PHE A CA 1 ATOM 583 C C . PHE A 1 74 ? -11.069 52.351 -81.475 1.00 28.24 ? 79 PHE A C 1 ATOM 584 O O . PHE A 1 74 ? -11.475 53.518 -81.568 1.00 24.19 ? 79 PHE A O 1 ATOM 585 C CB . PHE A 1 74 ? -9.134 52.970 -79.936 1.00 25.62 ? 79 PHE A CB 1 ATOM 586 C CG . PHE A 1 74 ? -8.199 52.471 -78.881 1.00 23.28 ? 79 PHE A CG 1 ATOM 587 C CD1 . PHE A 1 74 ? -6.819 52.284 -79.149 1.00 26.03 ? 79 PHE A CD1 1 ATOM 588 C CD2 . PHE A 1 74 ? -8.701 52.098 -77.640 1.00 25.37 ? 79 PHE A CD2 1 ATOM 589 C CE1 . PHE A 1 74 ? -5.945 51.751 -78.145 1.00 23.61 ? 79 PHE A CE1 1 ATOM 590 C CE2 . PHE A 1 74 ? -7.860 51.570 -76.653 1.00 28.16 ? 79 PHE A CE2 1 ATOM 591 C CZ . PHE A 1 74 ? -6.475 51.388 -76.928 1.00 23.94 ? 79 PHE A CZ 1 ATOM 592 N N . ILE A 1 75 ? -11.471 51.409 -82.316 1.00 23.77 ? 80 ILE A N 1 ATOM 593 C CA . ILE A 1 75 ? -12.292 51.771 -83.488 1.00 25.85 ? 80 ILE A CA 1 ATOM 594 C C . ILE A 1 75 ? -13.625 52.356 -83.049 1.00 25.56 ? 80 ILE A C 1 ATOM 595 O O . ILE A 1 75 ? -14.137 53.300 -83.663 1.00 26.48 ? 80 ILE A O 1 ATOM 596 C CB . ILE A 1 75 ? -12.471 50.523 -84.386 1.00 27.75 ? 80 ILE A CB 1 ATOM 597 C CG1 . ILE A 1 75 ? -11.198 50.297 -85.180 1.00 30.07 ? 80 ILE A CG1 1 ATOM 598 C CG2 . ILE A 1 75 ? -13.542 50.760 -85.430 1.00 33.41 ? 80 ILE A CG2 1 ATOM 599 C CD1 . ILE A 1 75 ? -11.247 49.052 -86.120 1.00 38.13 ? 80 ILE A CD1 1 ATOM 600 N N . ASN A 1 76 ? -14.189 51.801 -81.985 1.00 24.93 ? 81 ASN A N 1 ATOM 601 C CA . ASN A 1 76 ? -15.304 52.425 -81.264 1.00 21.01 ? 81 ASN A CA 1 ATOM 602 C C . ASN A 1 76 ? -15.004 52.213 -79.800 1.00 40.17 ? 81 ASN A C 1 ATOM 603 O O . ASN A 1 76 ? -14.543 51.106 -79.435 1.00 43.96 ? 81 ASN A O 1 ATOM 604 C CB . ASN A 1 76 ? -16.701 51.871 -81.657 1.00 26.05 ? 81 ASN A CB 1 ATOM 605 C CG . ASN A 1 76 ? -17.046 52.129 -83.119 1.00 23.89 ? 81 ASN A CG 1 ATOM 606 O OD1 . ASN A 1 76 ? -16.823 51.256 -83.998 1.00 26.86 ? 81 ASN A OD1 1 ATOM 607 N ND2 . ASN A 1 76 ? -17.585 53.277 -83.406 1.00 19.54 ? 81 ASN A ND2 1 ATOM 608 N N . VAL A 1 77 ? -15.104 53.281 -78.998 1.00 23.38 ? 82 VAL A N 1 ATOM 609 C CA . VAL A 1 77 ? -14.806 53.136 -77.571 1.00 22.77 ? 82 VAL A CA 1 ATOM 610 C C . VAL A 1 77 ? -15.996 53.552 -76.759 1.00 23.23 ? 82 VAL A C 1 ATOM 611 O O . VAL A 1 77 ? -16.745 54.482 -77.149 1.00 26.05 ? 82 VAL A O 1 ATOM 612 C CB . VAL A 1 77 ? -13.504 53.914 -77.124 1.00 27.01 ? 82 VAL A CB 1 ATOM 613 C CG1 . VAL A 1 77 ? -12.350 53.612 -78.045 1.00 26.77 ? 82 VAL A CG1 1 ATOM 614 C CG2 . VAL A 1 77 ? -13.772 55.417 -77.102 1.00 26.00 ? 82 VAL A CG2 1 ATOM 615 N N . PRO A 1 78 ? -16.242 52.840 -75.642 1.00 24.57 ? 83 PRO A N 1 ATOM 616 C CA . PRO A 1 78 ? -17.392 53.175 -74.821 1.00 22.06 ? 83 PRO A CA 1 ATOM 617 C C . PRO A 1 78 ? -17.138 54.424 -73.948 1.00 21.87 ? 83 PRO A C 1 ATOM 618 O O . PRO A 1 78 ? -16.036 54.915 -74.003 1.00 25.07 ? 83 PRO A O 1 ATOM 619 C CB . PRO A 1 78 ? -17.594 51.949 -73.932 1.00 26.64 ? 83 PRO A CB 1 ATOM 620 C CG . PRO A 1 78 ? -16.228 51.278 -73.881 1.00 26.58 ? 83 PRO A CG 1 ATOM 621 C CD . PRO A 1 78 ? -15.581 51.593 -75.219 1.00 25.92 ? 83 PRO A CD 1 ATOM 622 N N . GLU A 1 79 A -18.151 54.895 -73.261 1.00 27.57 ? 83 GLU A N 1 ATOM 623 C CA . GLU A 1 79 A -18.032 56.085 -72.407 1.00 24.63 ? 83 GLU A CA 1 ATOM 624 C C . GLU A 1 79 A -16.870 55.876 -71.413 1.00 26.50 ? 83 GLU A C 1 ATOM 625 O O . GLU A 1 79 A -16.676 54.790 -70.899 1.00 27.90 ? 83 GLU A O 1 ATOM 626 C CB . GLU A 1 79 A -19.330 56.259 -71.652 1.00 28.00 ? 83 GLU A CB 1 ATOM 627 C CG . GLU A 1 79 A -19.336 57.460 -70.697 1.00 33.50 ? 83 GLU A CG 1 ATOM 628 C CD . GLU A 1 79 A -20.658 57.563 -69.909 1.00 47.18 ? 83 GLU A CD 1 ATOM 629 O OE1 . GLU A 1 79 A -21.678 56.996 -70.362 1.00 45.83 ? 83 GLU A OE1 1 ATOM 630 O OE2 . GLU A 1 79 A -20.656 58.192 -68.832 1.00 49.52 ? 83 GLU A OE2 1 ATOM 631 N N . TRP A 1 80 ? -16.066 56.907 -71.173 1.00 25.57 ? 84 TRP A N 1 ATOM 632 C CA . TRP A 1 80 ? -14.913 56.748 -70.259 1.00 24.87 ? 84 TRP A CA 1 ATOM 633 C C . TRP A 1 80 ? -15.008 57.805 -69.144 1.00 26.32 ? 84 TRP A C 1 ATOM 634 O O . TRP A 1 80 ? -15.735 58.799 -69.276 1.00 25.27 ? 84 TRP A O 1 ATOM 635 C CB . TRP A 1 80 ? -13.583 56.898 -71.024 1.00 23.73 ? 84 TRP A CB 1 ATOM 636 C CG . TRP A 1 80 ? -13.485 58.272 -71.659 1.00 24.03 ? 84 TRP A CG 1 ATOM 637 C CD1 . TRP A 1 80 ? -12.988 59.427 -71.047 1.00 27.08 ? 84 TRP A CD1 1 ATOM 638 C CD2 . TRP A 1 80 ? -13.855 58.667 -73.009 1.00 23.02 ? 84 TRP A CD2 1 ATOM 639 N NE1 . TRP A 1 80 ? -13.045 60.497 -71.939 1.00 25.59 ? 84 TRP A NE1 1 ATOM 640 C CE2 . TRP A 1 80 ? -13.565 60.053 -73.137 1.00 23.72 ? 84 TRP A CE2 1 ATOM 641 C CE3 . TRP A 1 80 ? -14.369 57.968 -74.140 1.00 26.14 ? 84 TRP A CE3 1 ATOM 642 C CZ2 . TRP A 1 80 ? -13.819 60.778 -74.309 1.00 21.37 ? 84 TRP A CZ2 1 ATOM 643 C CZ3 . TRP A 1 80 ? -14.617 58.699 -75.308 1.00 26.85 ? 84 TRP A CZ3 1 ATOM 644 C CH2 . TRP A 1 80 ? -14.342 60.089 -75.388 1.00 25.26 ? 84 TRP A CH2 1 ATOM 645 N N . SER A 1 81 ? -14.257 57.582 -68.092 1.00 27.51 ? 85 SER A N 1 ATOM 646 C CA . SER A 1 81 ? -14.148 58.523 -66.967 1.00 26.49 ? 85 SER A CA 1 ATOM 647 C C . SER A 1 81 ? -12.930 59.461 -67.095 1.00 25.28 ? 85 SER A C 1 ATOM 648 O O . SER A 1 81 ? -13.047 60.652 -66.773 1.00 36.11 ? 85 SER A O 1 ATOM 649 C CB . SER A 1 81 ? -14.032 57.748 -65.667 1.00 23.73 ? 85 SER A CB 1 ATOM 650 O OG . SER A 1 81 ? -13.098 56.705 -65.782 1.00 26.87 ? 85 SER A OG 1 ATOM 651 N N . TYR A 1 82 ? -11.793 58.918 -67.509 1.00 22.52 ? 86 TYR A N 1 ATOM 652 C CA . TYR A 1 82 ? -10.602 59.696 -67.820 1.00 22.67 ? 86 TYR A CA 1 ATOM 653 C C . TYR A 1 82 ? -9.867 58.939 -68.888 1.00 28.71 ? 86 TYR A C 1 ATOM 654 O O . TYR A 1 82 ? -10.150 57.763 -69.129 1.00 26.59 ? 86 TYR A O 1 ATOM 655 C CB . TYR A 1 82 ? -9.669 59.882 -66.600 1.00 23.04 ? 86 TYR A CB 1 ATOM 656 C CG . TYR A 1 82 ? -9.192 58.633 -65.851 1.00 22.23 ? 86 TYR A CG 1 ATOM 657 C CD1 . TYR A 1 82 ? -7.897 58.179 -65.999 1.00 21.38 ? 86 TYR A CD1 1 ATOM 658 C CD2 . TYR A 1 82 ? -10.043 57.929 -65.011 1.00 25.30 ? 86 TYR A CD2 1 ATOM 659 C CE1 . TYR A 1 82 ? -7.460 57.020 -65.367 1.00 24.24 ? 86 TYR A CE1 1 ATOM 660 C CE2 . TYR A 1 82 ? -9.584 56.792 -64.310 1.00 24.41 ? 86 TYR A CE2 1 ATOM 661 C CZ . TYR A 1 82 ? -8.325 56.339 -64.509 1.00 22.83 ? 86 TYR A CZ 1 ATOM 662 O OH . TYR A 1 82 ? -7.862 55.195 -63.872 1.00 23.72 ? 86 TYR A OH 1 ATOM 663 N N . ILE A 1 83 ? -8.915 59.588 -69.532 1.00 22.34 ? 87 ILE A N 1 ATOM 664 C CA . ILE A 1 83 ? -8.128 58.938 -70.577 1.00 21.13 ? 87 ILE A CA 1 ATOM 665 C C . ILE A 1 83 ? -6.711 58.806 -70.108 1.00 24.33 ? 87 ILE A C 1 ATOM 666 O O . ILE A 1 83 ? -6.174 59.723 -69.452 1.00 26.70 ? 87 ILE A O 1 ATOM 667 C CB . ILE A 1 83 ? -8.146 59.800 -71.877 1.00 23.35 ? 87 ILE A CB 1 ATOM 668 C CG1 . ILE A 1 83 ? -9.605 59.997 -72.329 1.00 25.64 ? 87 ILE A CG1 1 ATOM 669 C CG2 . ILE A 1 83 ? -7.247 59.201 -73.004 1.00 23.24 ? 87 ILE A CG2 1 ATOM 670 C CD1 . ILE A 1 83 ? -9.747 60.901 -73.539 1.00 26.86 ? 87 ILE A CD1 1 ATOM 671 N N . VAL A 1 84 ? -6.092 57.674 -70.421 1.00 23.19 ? 88 VAL A N 1 ATOM 672 C CA . VAL A 1 84 ? -4.689 57.467 -70.080 1.00 21.75 ? 88 VAL A CA 1 ATOM 673 C C . VAL A 1 84 ? -3.843 57.315 -71.316 1.00 29.08 ? 88 VAL A C 1 ATOM 674 O O . VAL A 1 84 ? -4.108 56.473 -72.199 1.00 25.83 ? 88 VAL A O 1 ATOM 675 C CB . VAL A 1 84 ? -4.515 56.239 -69.173 1.00 24.25 ? 88 VAL A CB 1 ATOM 676 C CG1 . VAL A 1 84 ? -3.006 56.041 -68.836 1.00 26.20 ? 88 VAL A CG1 1 ATOM 677 C CG2 . VAL A 1 84 ? -5.421 56.368 -67.942 1.00 29.17 ? 88 VAL A CG2 1 ATOM 678 N N . GLU A 1 85 ? -2.824 58.157 -71.419 1.00 19.98 ? 89 GLU A N 1 ATOM 679 C CA . GLU A 1 85 ? -1.955 58.124 -72.586 1.00 22.84 ? 89 GLU A CA 1 ATOM 680 C C . GLU A 1 85 ? -0.532 57.949 -72.116 1.00 30.34 ? 89 GLU A C 1 ATOM 681 O O . GLU A 1 85 ? -0.133 58.578 -71.133 1.00 26.83 ? 89 GLU A O 1 ATOM 682 C CB . GLU A 1 85 ? -2.092 59.425 -73.395 1.00 23.33 ? 89 GLU A CB 1 ATOM 683 C CG . GLU A 1 85 ? -1.434 59.405 -74.782 1.00 24.58 ? 89 GLU A CG 1 ATOM 684 C CD . GLU A 1 85 ? -1.454 60.739 -75.484 1.00 32.82 ? 89 GLU A CD 1 ATOM 685 O OE1 . GLU A 1 85 ? -1.154 61.788 -74.849 1.00 28.87 ? 89 GLU A OE1 1 ATOM 686 O OE2 . GLU A 1 85 ? -1.783 60.757 -76.695 1.00 23.65 ? 89 GLU A OE2 1 ATOM 687 N N . LYS A 1 86 ? 0.252 57.135 -72.814 1.00 24.07 ? 90 LYS A N 1 ATOM 688 C CA . LYS A 1 86 ? 1.681 57.038 -72.453 1.00 28.12 ? 90 LYS A CA 1 ATOM 689 C C . LYS A 1 86 ? 2.456 58.291 -72.800 1.00 29.13 ? 90 LYS A C 1 ATOM 690 O O . LYS A 1 86 ? 1.980 59.117 -73.569 1.00 26.43 ? 90 LYS A O 1 ATOM 691 C CB . LYS A 1 86 ? 2.314 55.811 -73.073 1.00 28.30 ? 90 LYS A CB 1 ATOM 692 C CG . LYS A 1 86 ? 1.802 54.566 -72.478 1.00 27.63 ? 90 LYS A CG 1 ATOM 693 C CD . LYS A 1 86 ? 2.562 53.314 -73.037 1.00 30.68 ? 90 LYS A CD 1 ATOM 694 C CE . LYS A 1 86 ? 1.825 52.010 -72.723 1.00 33.26 ? 90 LYS A CE 1 ATOM 695 N NZ . LYS A 1 86 ? 1.734 51.595 -71.319 1.00 36.92 ? 90 LYS A NZ 1 ATOM 696 N N . ALA A 1 87 ? 3.659 58.464 -72.221 1.00 27.84 ? 91 ALA A N 1 ATOM 697 C CA . ALA A 1 87 ? 4.453 59.656 -72.522 1.00 33.09 ? 91 ALA A CA 1 ATOM 698 C C . ALA A 1 87 ? 4.814 59.789 -73.987 1.00 31.69 ? 91 ALA A C 1 ATOM 699 O O . ALA A 1 87 ? 4.793 60.882 -74.543 1.00 33.07 ? 91 ALA A O 1 ATOM 700 C CB . ALA A 1 87 ? 5.748 59.684 -71.648 1.00 33.10 ? 91 ALA A CB 1 ATOM 701 N N . ASN A 1 88 ? 5.179 58.670 -74.603 1.00 30.13 ? 92 ASN A N 1 ATOM 702 C CA . ASN A 1 88 ? 5.590 58.651 -75.995 1.00 35.64 ? 92 ASN A CA 1 ATOM 703 C C . ASN A 1 88 ? 4.996 57.418 -76.687 1.00 35.37 ? 92 ASN A C 1 ATOM 704 O O . ASN A 1 88 ? 5.691 56.430 -76.921 1.00 33.54 ? 92 ASN A O 1 ATOM 705 C CB . ASN A 1 88 ? 7.115 58.658 -76.106 1.00 38.87 ? 92 ASN A CB 1 ATOM 706 C CG . ASN A 1 88 ? 7.731 59.876 -75.429 1.00 45.49 ? 92 ASN A CG 1 ATOM 707 O OD1 . ASN A 1 88 ? 7.656 60.993 -75.953 1.00 43.27 ? 92 ASN A OD1 1 ATOM 708 N ND2 . ASN A 1 88 ? 8.298 59.675 -74.243 1.00 43.39 ? 92 ASN A ND2 1 ATOM 709 N N . PRO A 1 89 ? 3.690 57.461 -76.981 1.00 31.54 ? 93 PRO A N 1 ATOM 710 C CA . PRO A 1 89 ? 3.043 56.313 -77.660 1.00 32.12 ? 93 PRO A CA 1 ATOM 711 C C . PRO A 1 89 ? 3.676 56.001 -79.011 1.00 30.03 ? 93 PRO A C 1 ATOM 712 O O . PRO A 1 89 ? 3.946 56.927 -79.776 1.00 33.60 ? 93 PRO A O 1 ATOM 713 C CB . PRO A 1 89 ? 1.618 56.822 -77.916 1.00 29.63 ? 93 PRO A CB 1 ATOM 714 C CG . PRO A 1 89 ? 1.431 58.009 -76.958 1.00 30.40 ? 93 PRO A CG 1 ATOM 715 C CD . PRO A 1 89 ? 2.792 58.641 -76.882 1.00 31.75 ? 93 PRO A CD 1 ATOM 716 N N . VAL A 1 90 ? 3.897 54.722 -79.309 1.00 29.28 ? 94 VAL A N 1 ATOM 717 C CA . VAL A 1 90 ? 4.563 54.369 -80.560 1.00 33.45 ? 94 VAL A CA 1 ATOM 718 C C . VAL A 1 90 ? 3.632 54.455 -81.784 1.00 32.15 ? 94 VAL A C 1 ATOM 719 O O . VAL A 1 90 ? 4.085 54.702 -82.901 1.00 32.53 ? 94 VAL A O 1 ATOM 720 C CB . VAL A 1 90 ? 5.229 52.967 -80.462 1.00 38.27 ? 94 VAL A CB 1 ATOM 721 C CG1 . VAL A 1 90 ? 6.182 52.909 -79.234 1.00 45.02 ? 94 VAL A CG1 1 ATOM 722 C CG2 . VAL A 1 90 ? 4.172 51.894 -80.392 1.00 43.52 ? 94 VAL A CG2 1 ATOM 723 N N . ASN A 1 91 ? 2.330 54.310 -81.559 1.00 30.73 ? 95 ASN A N 1 ATOM 724 C CA . ASN A 1 91 ? 1.359 54.396 -82.667 1.00 23.13 ? 95 ASN A CA 1 ATOM 725 C C . ASN A 1 91 ? 0.665 55.761 -82.704 1.00 25.08 ? 95 ASN A C 1 ATOM 726 O O . ASN A 1 91 ? -0.287 55.996 -81.963 1.00 31.37 ? 95 ASN A O 1 ATOM 727 C CB . ASN A 1 91 ? 0.325 53.263 -82.553 1.00 25.03 ? 95 ASN A CB 1 ATOM 728 C CG . ASN A 1 91 ? 1.005 51.891 -82.631 1.00 31.13 ? 95 ASN A CG 1 ATOM 729 O OD1 . ASN A 1 91 ? 1.883 51.708 -83.457 1.00 29.50 ? 95 ASN A OD1 1 ATOM 730 N ND2 . ASN A 1 91 ? 0.629 50.958 -81.742 1.00 36.59 ? 95 ASN A ND2 1 ATOM 731 N N . ASP A 1 92 ? 1.148 56.621 -83.575 1.00 26.48 ? 96 ASP A N 1 ATOM 732 C CA . ASP A 1 92 ? 0.740 58.016 -83.607 1.00 28.01 ? 96 ASP A CA 1 ATOM 733 C C . ASP A 1 92 ? 0.450 58.340 -85.043 1.00 25.94 ? 96 ASP A C 1 ATOM 734 O O . ASP A 1 92 ? -0.483 57.773 -85.607 1.00 29.04 ? 96 ASP A O 1 ATOM 735 C CB . ASP A 1 92 ? 1.883 58.863 -83.059 1.00 30.08 ? 96 ASP A CB 1 ATOM 736 C CG . ASP A 1 92 ? 1.560 60.347 -83.016 1.00 32.74 ? 96 ASP A CG 1 ATOM 737 O OD1 . ASP A 1 92 ? 0.455 60.719 -82.595 1.00 28.56 ? 96 ASP A OD1 1 ATOM 738 O OD2 . ASP A 1 92 ? 2.419 61.148 -83.423 1.00 34.01 ? 96 ASP A OD2 1 ATOM 739 N N . LEU A 1 93 A 1.254 59.192 -85.680 1.00 24.87 ? 96 LEU A N 1 ATOM 740 C CA . LEU A 1 93 A 1.017 59.488 -87.079 1.00 25.69 ? 96 LEU A CA 1 ATOM 741 C C . LEU A 1 93 A 1.863 58.483 -87.913 1.00 30.77 ? 96 LEU A C 1 ATOM 742 O O . LEU A 1 93 A 3.046 58.740 -88.182 1.00 32.02 ? 96 LEU A O 1 ATOM 743 C CB . LEU A 1 93 A 1.433 60.899 -87.441 1.00 27.66 ? 96 LEU A CB 1 ATOM 744 C CG . LEU A 1 93 A 0.578 62.015 -86.793 1.00 26.59 ? 96 LEU A CG 1 ATOM 745 C CD1 . LEU A 1 93 A 0.919 63.428 -87.340 1.00 26.24 ? 96 LEU A CD1 1 ATOM 746 C CD2 . LEU A 1 93 A -0.935 61.734 -86.917 1.00 24.91 ? 96 LEU A CD2 1 ATOM 747 N N . CYS A 1 94 ? 1.264 57.356 -88.280 1.00 27.52 ? 97 CYS A N 1 ATOM 748 C CA . CYS A 1 94 ? 2.019 56.349 -89.045 1.00 29.41 ? 97 CYS A CA 1 ATOM 749 C C . CYS A 1 94 ? 2.609 56.909 -90.341 1.00 29.12 ? 97 CYS A C 1 ATOM 750 O O . CYS A 1 94 ? 3.805 56.735 -90.617 1.00 33.96 ? 97 CYS A O 1 ATOM 751 C CB . CYS A 1 94 ? 1.178 55.073 -89.218 1.00 34.04 ? 97 CYS A CB 1 ATOM 752 S SG . CYS A 1 94 ? -0.440 55.315 -90.007 1.00 34.34 ? 97 CYS A SG 1 ATOM 753 N N . TYR A 1 95 ? 1.807 57.622 -91.118 1.00 26.65 ? 98 TYR A N 1 ATOM 754 C CA . TYR A 1 95 ? 2.318 58.400 -92.229 1.00 26.44 ? 98 TYR A CA 1 ATOM 755 C C . TYR A 1 95 ? 2.662 59.735 -91.593 1.00 32.31 ? 98 TYR A C 1 ATOM 756 O O . TYR A 1 95 ? 1.780 60.376 -90.972 1.00 28.86 ? 98 TYR A O 1 ATOM 757 C CB . TYR A 1 95 ? 1.287 58.630 -93.303 1.00 27.31 ? 98 TYR A CB 1 ATOM 758 C CG . TYR A 1 95 ? 1.866 59.093 -94.611 1.00 35.82 ? 98 TYR A CG 1 ATOM 759 C CD1 . TYR A 1 95 ? 1.924 58.245 -95.742 1.00 28.36 ? 98 TYR A CD1 1 ATOM 760 C CD2 . TYR A 1 95 ? 2.374 60.392 -94.743 1.00 29.81 ? 98 TYR A CD2 1 ATOM 761 C CE1 . TYR A 1 95 ? 2.465 58.713 -96.937 1.00 29.69 ? 98 TYR A CE1 1 ATOM 762 C CE2 . TYR A 1 95 ? 2.898 60.845 -95.930 1.00 29.57 ? 98 TYR A CE2 1 ATOM 763 C CZ . TYR A 1 95 ? 2.968 59.997 -97.027 1.00 35.07 ? 98 TYR A CZ 1 ATOM 764 O OH . TYR A 1 95 ? 3.509 60.475 -98.212 1.00 31.38 ? 98 TYR A OH 1 ATOM 765 N N . PRO A 1 96 ? 3.928 60.148 -91.718 1.00 30.47 ? 99 PRO A N 1 ATOM 766 C CA . PRO A 1 96 ? 4.391 61.294 -90.917 1.00 30.42 ? 99 PRO A CA 1 ATOM 767 C C . PRO A 1 96 ? 3.727 62.601 -91.308 1.00 28.64 ? 99 PRO A C 1 ATOM 768 O O . PRO A 1 96 ? 3.235 62.793 -92.412 1.00 29.05 ? 99 PRO A O 1 ATOM 769 C CB . PRO A 1 96 ? 5.914 61.350 -91.215 1.00 27.00 ? 99 PRO A CB 1 ATOM 770 C CG . PRO A 1 96 ? 5.985 60.770 -92.688 1.00 29.06 ? 99 PRO A CG 1 ATOM 771 C CD . PRO A 1 96 ? 4.998 59.593 -92.566 1.00 31.68 ? 99 PRO A CD 1 ATOM 772 N N . GLY A 1 97 ? 3.744 63.586 -90.382 1.00 25.38 ? 100 GLY A N 1 ATOM 773 C CA . GLY A 1 97 ? 3.173 64.878 -90.744 1.00 25.14 ? 100 GLY A CA 1 ATOM 774 C C . GLY A 1 97 ? 2.887 65.608 -89.429 1.00 29.70 ? 100 GLY A C 1 ATOM 775 O O . GLY A 1 97 ? 3.660 65.491 -88.486 1.00 27.03 ? 100 GLY A O 1 ATOM 776 N N . ASP A 1 98 ? 1.773 66.299 -89.370 1.00 24.70 ? 101 ASP A N 1 ATOM 777 C CA . ASP A 1 98 ? 1.457 67.088 -88.149 1.00 30.78 ? 101 ASP A CA 1 ATOM 778 C C . ASP A 1 98 ? -0.050 67.185 -87.982 1.00 31.94 ? 101 ASP A C 1 ATOM 779 O O . ASP A 1 98 ? -0.800 66.997 -88.925 1.00 28.85 ? 101 ASP A O 1 ATOM 780 C CB . ASP A 1 98 ? 2.040 68.502 -88.281 1.00 31.92 ? 101 ASP A CB 1 ATOM 781 C CG . ASP A 1 98 ? 1.955 69.304 -86.948 1.00 38.08 ? 101 ASP A CG 1 ATOM 782 O OD1 . ASP A 1 98 ? 2.035 68.682 -85.851 1.00 35.74 ? 101 ASP A OD1 1 ATOM 783 O OD2 . ASP A 1 98 ? 1.771 70.533 -87.028 1.00 58.35 ? 101 ASP A OD2 1 ATOM 784 N N . PHE A 1 99 ? -0.515 67.516 -86.778 1.00 27.00 ? 102 PHE A N 1 ATOM 785 C CA . PHE A 1 99 ? -1.941 67.613 -86.569 1.00 22.86 ? 102 PHE A CA 1 ATOM 786 C C . PHE A 1 99 ? -2.094 69.005 -86.035 1.00 26.42 ? 102 PHE A C 1 ATOM 787 O O . PHE A 1 99 ? -1.560 69.300 -84.953 1.00 26.82 ? 102 PHE A O 1 ATOM 788 C CB . PHE A 1 99 ? -2.271 66.589 -85.510 1.00 24.50 ? 102 PHE A CB 1 ATOM 789 C CG . PHE A 1 99 ? -3.743 66.292 -85.323 1.00 25.80 ? 102 PHE A CG 1 ATOM 790 C CD1 . PHE A 1 99 ? -4.187 64.971 -85.345 1.00 24.91 ? 102 PHE A CD1 1 ATOM 791 C CD2 . PHE A 1 99 ? -4.651 67.284 -85.006 1.00 29.38 ? 102 PHE A CD2 1 ATOM 792 C CE1 . PHE A 1 99 ? -5.510 64.626 -85.128 1.00 32.01 ? 102 PHE A CE1 1 ATOM 793 C CE2 . PHE A 1 99 ? -6.002 66.962 -84.772 1.00 38.56 ? 102 PHE A CE2 1 ATOM 794 C CZ . PHE A 1 99 ? -6.442 65.620 -84.846 1.00 35.37 ? 102 PHE A CZ 1 ATOM 795 N N . ASN A 1 100 ? -2.779 69.849 -86.788 1.00 21.53 ? 103 ASN A N 1 ATOM 796 C CA . ASN A 1 100 ? -2.904 71.267 -86.456 1.00 23.91 ? 103 ASN A CA 1 ATOM 797 C C . ASN A 1 100 ? -3.690 71.502 -85.162 1.00 24.56 ? 103 ASN A C 1 ATOM 798 O O . ASN A 1 100 ? -4.735 70.866 -84.952 1.00 22.09 ? 103 ASN A O 1 ATOM 799 C CB . ASN A 1 100 ? -3.666 71.908 -87.573 1.00 27.26 ? 103 ASN A CB 1 ATOM 800 C CG . ASN A 1 100 ? -3.565 73.372 -87.557 1.00 36.48 ? 103 ASN A CG 1 ATOM 801 O OD1 . ASN A 1 100 ? -2.461 73.926 -87.739 1.00 35.03 ? 103 ASN A OD1 1 ATOM 802 N ND2 . ASN A 1 100 ? -4.721 74.043 -87.399 1.00 34.51 ? 103 ASN A ND2 1 ATOM 803 N N . ASP A 1 101 ? -3.248 72.471 -84.338 1.00 22.61 ? 104 ASP A N 1 ATOM 804 C CA . ASP A 1 101 ? -3.920 72.698 -83.041 1.00 19.41 ? 104 ASP A CA 1 ATOM 805 C C . ASP A 1 101 ? -4.221 71.451 -82.202 1.00 19.33 ? 104 ASP A C 1 ATOM 806 O O . ASP A 1 101 ? -5.294 71.314 -81.585 1.00 19.73 ? 104 ASP A O 1 ATOM 807 C CB . ASP A 1 101 ? -5.206 73.482 -83.255 1.00 21.63 ? 104 ASP A CB 1 ATOM 808 C CG . ASP A 1 101 ? -4.951 74.952 -83.637 1.00 33.83 ? 104 ASP A CG 1 ATOM 809 O OD1 . ASP A 1 101 ? -3.915 75.547 -83.290 1.00 38.29 ? 104 ASP A OD1 1 ATOM 810 O OD2 . ASP A 1 101 ? -5.822 75.519 -84.277 1.00 32.52 ? 104 ASP A OD2 1 ATOM 811 N N . TYR A 1 102 ? -3.250 70.558 -82.148 1.00 20.32 ? 105 TYR A N 1 ATOM 812 C CA . TYR A 1 102 ? -3.447 69.295 -81.470 1.00 21.61 ? 105 TYR A CA 1 ATOM 813 C C . TYR A 1 102 ? -3.678 69.495 -79.989 1.00 22.83 ? 105 TYR A C 1 ATOM 814 O O . TYR A 1 102 ? -4.465 68.798 -79.411 1.00 21.21 ? 105 TYR A O 1 ATOM 815 C CB . TYR A 1 102 ? -2.210 68.446 -81.722 1.00 22.59 ? 105 TYR A CB 1 ATOM 816 C CG . TYR A 1 102 ? -2.235 67.032 -81.208 1.00 21.53 ? 105 TYR A CG 1 ATOM 817 C CD1 . TYR A 1 102 ? -3.300 66.187 -81.485 1.00 21.19 ? 105 TYR A CD1 1 ATOM 818 C CD2 . TYR A 1 102 ? -1.153 66.522 -80.491 1.00 20.49 ? 105 TYR A CD2 1 ATOM 819 C CE1 . TYR A 1 102 ? -3.302 64.874 -81.041 1.00 22.19 ? 105 TYR A CE1 1 ATOM 820 C CE2 . TYR A 1 102 ? -1.128 65.207 -80.066 1.00 26.28 ? 105 TYR A CE2 1 ATOM 821 C CZ . TYR A 1 102 ? -2.212 64.384 -80.351 1.00 22.03 ? 105 TYR A CZ 1 ATOM 822 O OH . TYR A 1 102 ? -2.176 63.067 -79.916 1.00 24.84 ? 105 TYR A OH 1 ATOM 823 N N . GLU A 1 103 ? -2.910 70.405 -79.364 1.00 20.55 ? 106 GLU A N 1 ATOM 824 C CA . GLU A 1 103 ? -3.031 70.520 -77.914 1.00 21.49 ? 106 GLU A CA 1 ATOM 825 C C . GLU A 1 103 ? -4.367 71.094 -77.559 1.00 18.87 ? 106 GLU A C 1 ATOM 826 O O . GLU A 1 103 ? -4.933 70.761 -76.491 1.00 20.01 ? 106 GLU A O 1 ATOM 827 C CB . GLU A 1 103 ? -1.880 71.365 -77.327 1.00 19.83 ? 106 GLU A CB 1 ATOM 828 C CG . GLU A 1 103 ? -0.467 70.673 -77.441 1.00 22.17 ? 106 GLU A CG 1 ATOM 829 C CD . GLU A 1 103 ? 0.033 70.559 -78.889 1.00 28.18 ? 106 GLU A CD 1 ATOM 830 O OE1 . GLU A 1 103 ? -0.228 71.432 -79.740 1.00 26.15 ? 106 GLU A OE1 1 ATOM 831 O OE2 . GLU A 1 103 ? 0.761 69.593 -79.112 1.00 27.79 ? 106 GLU A OE2 1 ATOM 832 N N . GLU A 1 104 ? -4.842 72.027 -78.393 1.00 18.62 ? 107 GLU A N 1 ATOM 833 C CA . GLU A 1 104 ? -6.194 72.569 -78.167 1.00 18.32 ? 107 GLU A CA 1 ATOM 834 C C . GLU A 1 104 ? -7.276 71.492 -78.308 1.00 21.24 ? 107 GLU A C 1 ATOM 835 O O . GLU A 1 104 ? -8.257 71.487 -77.594 1.00 19.34 ? 107 GLU A O 1 ATOM 836 C CB . GLU A 1 104 ? -6.526 73.770 -79.072 1.00 19.35 ? 107 GLU A CB 1 ATOM 837 C CG . GLU A 1 104 ? -5.724 75.048 -78.641 1.00 17.84 ? 107 GLU A CG 1 ATOM 838 C CD . GLU A 1 104 ? -6.367 75.723 -77.394 1.00 17.32 ? 107 GLU A CD 1 ATOM 839 O OE1 . GLU A 1 104 ? -7.620 75.883 -77.389 1.00 18.65 ? 107 GLU A OE1 1 ATOM 840 O OE2 . GLU A 1 104 ? -5.601 76.096 -76.473 1.00 18.97 ? 107 GLU A OE2 1 ATOM 841 N N . LEU A 1 105 ? -7.074 70.548 -79.236 1.00 20.03 ? 108 LEU A N 1 ATOM 842 C CA . LEU A 1 105 ? -8.036 69.450 -79.339 1.00 21.59 ? 108 LEU A CA 1 ATOM 843 C C . LEU A 1 105 ? -7.962 68.571 -78.097 1.00 18.93 ? 108 LEU A C 1 ATOM 844 O O . LEU A 1 105 ? -8.986 68.147 -77.559 1.00 21.47 ? 108 LEU A O 1 ATOM 845 C CB . LEU A 1 105 ? -7.724 68.640 -80.611 1.00 21.74 ? 108 LEU A CB 1 ATOM 846 C CG . LEU A 1 105 ? -8.657 67.409 -80.749 1.00 23.32 ? 108 LEU A CG 1 ATOM 847 C CD1 . LEU A 1 105 ? -10.121 67.798 -80.770 1.00 22.80 ? 108 LEU A CD1 1 ATOM 848 C CD2 . LEU A 1 105 ? -8.278 66.700 -82.090 1.00 26.54 ? 108 LEU A CD2 1 ATOM 849 N N . LYS A 1 106 ? -6.762 68.317 -77.611 1.00 19.55 ? 109 LYS A N 1 ATOM 850 C CA . LYS A 1 106 ? -6.619 67.470 -76.438 1.00 19.11 ? 109 LYS A CA 1 ATOM 851 C C . LYS A 1 106 ? -7.295 68.161 -75.232 1.00 25.41 ? 109 LYS A C 1 ATOM 852 O O . LYS A 1 106 ? -7.956 67.525 -74.413 1.00 21.46 ? 109 LYS A O 1 ATOM 853 C CB . LYS A 1 106 ? -5.130 67.194 -76.123 1.00 21.86 ? 109 LYS A CB 1 ATOM 854 C CG . LYS A 1 106 ? -4.508 66.129 -77.062 1.00 23.32 ? 109 LYS A CG 1 ATOM 855 C CD . LYS A 1 106 ? -2.978 65.966 -76.822 1.00 27.35 ? 109 LYS A CD 1 ATOM 856 C CE . LYS A 1 106 ? -2.746 64.641 -76.188 1.00 29.51 ? 109 LYS A CE 1 ATOM 857 N NZ . LYS A 1 106 ? -1.282 64.404 -75.935 1.00 30.94 ? 109 LYS A NZ 1 ATOM 858 N N . HIS A 1 107 ? -7.202 69.485 -75.189 1.00 20.57 ? 110 HIS A N 1 ATOM 859 C CA . HIS A 1 107 ? -7.916 70.217 -74.152 1.00 19.80 ? 110 HIS A CA 1 ATOM 860 C C . HIS A 1 107 ? -9.437 70.021 -74.229 1.00 21.43 ? 110 HIS A C 1 ATOM 861 O O . HIS A 1 107 ? -10.093 69.835 -73.197 1.00 22.59 ? 110 HIS A O 1 ATOM 862 C CB . HIS A 1 107 ? -7.533 71.713 -74.206 1.00 21.07 ? 110 HIS A CB 1 ATOM 863 C CG . HIS A 1 107 ? -8.197 72.525 -73.125 1.00 23.52 ? 110 HIS A CG 1 ATOM 864 N ND1 . HIS A 1 107 ? -7.639 72.688 -71.883 1.00 28.85 ? 110 HIS A ND1 1 ATOM 865 C CD2 . HIS A 1 107 ? -9.394 73.145 -73.092 1.00 29.93 ? 110 HIS A CD2 1 ATOM 866 C CE1 . HIS A 1 107 ? -8.450 73.412 -71.133 1.00 33.00 ? 110 HIS A CE1 1 ATOM 867 N NE2 . HIS A 1 107 ? -9.523 73.702 -71.842 1.00 32.20 ? 110 HIS A NE2 1 ATOM 868 N N . LEU A 1 108 ? -9.996 70.077 -75.434 1.00 23.05 ? 111 LEU A N 1 ATOM 869 C CA A LEU A 1 108 ? -11.428 69.827 -75.602 0.50 21.59 ? 111 LEU A CA 1 ATOM 870 C CA B LEU A 1 108 ? -11.426 69.819 -75.634 0.50 21.59 ? 111 LEU A CA 1 ATOM 871 C C . LEU A 1 108 ? -11.797 68.424 -75.132 1.00 21.44 ? 111 LEU A C 1 ATOM 872 O O . LEU A 1 108 ? -12.822 68.219 -74.446 1.00 25.05 ? 111 LEU A O 1 ATOM 873 C CB A LEU A 1 108 ? -11.846 69.994 -77.059 0.50 25.79 ? 111 LEU A CB 1 ATOM 874 C CB B LEU A 1 108 ? -11.784 69.917 -77.121 0.50 25.79 ? 111 LEU A CB 1 ATOM 875 C CG A LEU A 1 108 ? -11.876 71.427 -77.572 0.50 26.61 ? 111 LEU A CG 1 ATOM 876 C CG B LEU A 1 108 ? -13.192 70.405 -77.439 0.50 35.13 ? 111 LEU A CG 1 ATOM 877 C CD1 A LEU A 1 108 ? -12.497 71.371 -78.956 0.50 33.80 ? 111 LEU A CD1 1 ATOM 878 C CD1 B LEU A 1 108 ? -13.436 71.729 -76.731 0.50 34.20 ? 111 LEU A CD1 1 ATOM 879 C CD2 A LEU A 1 108 ? -12.673 72.364 -76.676 0.50 34.29 ? 111 LEU A CD2 1 ATOM 880 C CD2 B LEU A 1 108 ? -13.319 70.591 -78.931 0.50 33.87 ? 111 LEU A CD2 1 ATOM 881 N N . LEU A 1 109 ? -10.946 67.473 -75.459 1.00 25.26 ? 112 LEU A N 1 ATOM 882 C CA . LEU A 1 109 ? -11.194 66.096 -75.082 1.00 24.03 ? 112 LEU A CA 1 ATOM 883 C C . LEU A 1 109 ? -11.246 65.922 -73.598 1.00 34.22 ? 112 LEU A C 1 ATOM 884 O O . LEU A 1 109 ? -11.902 65.012 -73.106 1.00 29.61 ? 112 LEU A O 1 ATOM 885 C CB . LEU A 1 109 ? -10.133 65.161 -75.643 1.00 28.26 ? 112 LEU A CB 1 ATOM 886 C CG . LEU A 1 109 ? -10.323 64.190 -76.741 1.00 43.21 ? 112 LEU A CG 1 ATOM 887 C CD1 . LEU A 1 109 ? -9.035 63.392 -76.678 1.00 35.63 ? 112 LEU A CD1 1 ATOM 888 C CD2 . LEU A 1 109 ? -11.553 63.317 -76.486 1.00 32.92 ? 112 LEU A CD2 1 ATOM 889 N N . SER A 1 110 ? -10.604 66.840 -72.870 1.00 29.32 ? 113 SER A N 1 ATOM 890 C CA . SER A 1 110 ? -10.559 66.768 -71.438 1.00 38.51 ? 113 SER A CA 1 ATOM 891 C C . SER A 1 110 ? -11.894 67.110 -70.770 1.00 31.54 ? 113 SER A C 1 ATOM 892 O O . SER A 1 110 ? -12.062 66.841 -69.601 1.00 44.24 ? 113 SER A O 1 ATOM 893 C CB . SER A 1 110 ? -9.369 67.633 -70.912 1.00 36.55 ? 113 SER A CB 1 ATOM 894 O OG . SER A 1 110 ? -8.131 67.069 -71.409 1.00 39.80 ? 113 SER A OG 1 ATOM 895 N N . ARG A 1 111 ? -12.876 67.613 -71.542 1.00 30.52 ? 114 ARG A N 1 ATOM 896 C CA . ARG A 1 111 ? -14.231 67.812 -71.074 1.00 31.87 ? 114 ARG A CA 1 ATOM 897 C C . ARG A 1 111 ? -15.289 66.951 -71.789 1.00 31.59 ? 114 ARG A C 1 ATOM 898 O O . ARG A 1 111 ? -16.480 67.275 -71.777 1.00 28.46 ? 114 ARG A O 1 ATOM 899 C CB . ARG A 1 111 ? -14.656 69.265 -71.281 1.00 49.21 ? 114 ARG A CB 1 ATOM 900 C CG . ARG A 1 111 ? -13.979 70.214 -70.325 1.00 56.32 ? 114 ARG A CG 1 ATOM 901 C CD . ARG A 1 111 ? -12.775 70.912 -70.971 1.00 59.68 ? 114 ARG A CD 1 ATOM 902 N NE . ARG A 1 111 ? -12.633 72.252 -70.408 1.00 66.64 ? 114 ARG A NE 1 ATOM 903 C CZ . ARG A 1 111 ? -11.867 72.556 -69.366 1.00 67.98 ? 114 ARG A CZ 1 ATOM 904 N NH1 . ARG A 1 111 ? -11.120 71.608 -68.785 1.00 55.63 ? 114 ARG A NH1 1 ATOM 905 N NH2 . ARG A 1 111 ? -11.834 73.821 -68.926 1.00 61.51 ? 114 ARG A NH2 1 ATOM 906 N N . ILE A 1 112 ? -14.839 65.898 -72.466 1.00 25.84 ? 115 ILE A N 1 ATOM 907 C CA . ILE A 1 112 ? -15.785 64.989 -73.197 1.00 23.66 ? 115 ILE A CA 1 ATOM 908 C C . ILE A 1 112 ? -15.666 63.582 -72.569 1.00 19.42 ? 115 ILE A C 1 ATOM 909 O O . ILE A 1 112 ? -14.541 63.153 -72.200 1.00 25.48 ? 115 ILE A O 1 ATOM 910 C CB . ILE A 1 112 ? -15.353 64.920 -74.667 1.00 20.82 ? 115 ILE A CB 1 ATOM 911 C CG1 . ILE A 1 112 ? -15.557 66.289 -75.339 1.00 23.87 ? 115 ILE A CG1 1 ATOM 912 C CG2 . ILE A 1 112 ? -16.111 63.674 -75.343 1.00 22.81 ? 115 ILE A CG2 1 ATOM 913 C CD1 . ILE A 1 112 ? -15.067 66.348 -76.760 1.00 22.57 ? 115 ILE A CD1 1 ATOM 914 N N . ASN A 1 113 ? -16.802 62.837 -72.418 1.00 21.29 ? 116 ASN A N 1 ATOM 915 C CA . ASN A 1 113 ? -16.676 61.517 -71.811 1.00 21.79 ? 116 ASN A CA 1 ATOM 916 C C . ASN A 1 113 ? -17.125 60.427 -72.819 1.00 23.03 ? 116 ASN A C 1 ATOM 917 O O . ASN A 1 113 ? -16.932 59.237 -72.555 1.00 24.46 ? 116 ASN A O 1 ATOM 918 C CB . ASN A 1 113 ? -17.607 61.369 -70.613 1.00 23.60 ? 116 ASN A CB 1 ATOM 919 C CG . ASN A 1 113 ? -17.187 62.213 -69.431 1.00 28.57 ? 116 ASN A CG 1 ATOM 920 O OD1 . ASN A 1 113 ? -17.894 63.139 -69.049 1.00 34.40 ? 116 ASN A OD1 1 ATOM 921 N ND2 . ASN A 1 113 ? -16.045 61.878 -68.838 1.00 28.51 ? 116 ASN A ND2 1 ATOM 922 N N . HIS A 1 114 ? -17.743 60.820 -73.914 1.00 21.00 ? 117 HIS A N 1 ATOM 923 C CA . HIS A 1 114 ? -18.189 59.778 -74.904 1.00 22.60 ? 117 HIS A CA 1 ATOM 924 C C . HIS A 1 114 ? -18.459 60.389 -76.255 1.00 24.62 ? 117 HIS A C 1 ATOM 925 O O . HIS A 1 114 ? -19.093 61.451 -76.344 1.00 24.37 ? 117 HIS A O 1 ATOM 926 C CB . HIS A 1 114 ? -19.483 59.089 -74.478 1.00 25.39 ? 117 HIS A CB 1 ATOM 927 C CG . HIS A 1 114 ? -19.739 57.811 -75.238 1.00 23.82 ? 117 HIS A CG 1 ATOM 928 N ND1 . HIS A 1 114 ? -20.997 57.281 -75.443 1.00 32.51 ? 117 HIS A ND1 1 ATOM 929 C CD2 . HIS A 1 114 ? -18.854 56.914 -75.758 1.00 27.36 ? 117 HIS A CD2 1 ATOM 930 C CE1 . HIS A 1 114 ? -20.882 56.132 -76.105 1.00 31.69 ? 117 HIS A CE1 1 ATOM 931 N NE2 . HIS A 1 114 ? -19.597 55.888 -76.307 1.00 35.41 ? 117 HIS A NE2 1 ATOM 932 N N . PHE A 1 115 ? -17.737 59.591 -77.436 1.00 24.86 ? 118 PHE A N 1 ATOM 933 C CA . PHE A 1 115 ? -18.270 59.906 -78.776 1.00 21.61 ? 118 PHE A CA 1 ATOM 934 C C . PHE A 1 115 ? -19.290 58.904 -79.242 1.00 24.03 ? 118 PHE A C 1 ATOM 935 O O . PHE A 1 115 ? -19.283 57.745 -78.777 1.00 23.72 ? 118 PHE A O 1 ATOM 936 C CB . PHE A 1 115 ? -17.128 59.990 -79.789 1.00 20.00 ? 118 PHE A CB 1 ATOM 937 C CG . PHE A 1 115 ? -16.158 61.105 -79.518 1.00 20.00 ? 118 PHE A CG 1 ATOM 938 C CD1 . PHE A 1 115 ? -16.426 62.395 -79.944 1.00 20.00 ? 118 PHE A CD1 1 ATOM 939 C CD2 . PHE A 1 115 ? -14.977 60.863 -78.835 1.00 20.00 ? 118 PHE A CD2 1 ATOM 940 C CE1 . PHE A 1 115 ? -15.536 63.421 -79.694 1.00 20.00 ? 118 PHE A CE1 1 ATOM 941 C CE2 . PHE A 1 115 ? -14.083 61.886 -78.585 1.00 20.00 ? 118 PHE A CE2 1 ATOM 942 C CZ . PHE A 1 115 ? -14.363 63.167 -79.014 1.00 20.00 ? 118 PHE A CZ 1 ATOM 943 N N . GLU A 1 116 ? -20.049 59.232 -80.318 1.00 22.13 ? 119 GLU A N 1 ATOM 944 C CA . GLU A 1 116 ? -20.551 58.171 -81.242 1.00 22.45 ? 119 GLU A CA 1 ATOM 945 C C . GLU A 1 116 ? -19.919 58.501 -82.565 1.00 23.08 ? 119 GLU A C 1 ATOM 946 O O . GLU A 1 116 ? -20.158 59.551 -83.180 1.00 22.86 ? 119 GLU A O 1 ATOM 947 C CB . GLU A 1 116 ? -22.110 58.240 -81.378 1.00 25.61 ? 119 GLU A CB 1 ATOM 948 C CG . GLU A 1 116 ? -22.798 57.643 -80.202 1.00 28.53 ? 119 GLU A CG 1 ATOM 949 C CD . GLU A 1 116 ? -24.335 57.768 -80.296 1.00 31.32 ? 119 GLU A CD 1 ATOM 950 O OE1 . GLU A 1 116 ? -24.846 58.279 -81.319 1.00 29.75 ? 119 GLU A OE1 1 ATOM 951 O OE2 . GLU A 1 116 ? -24.976 57.341 -79.318 1.00 37.24 ? 119 GLU A OE2 1 ATOM 952 N N . LYS A 1 117 ? -19.098 57.594 -83.062 1.00 22.50 ? 120 LYS A N 1 ATOM 953 C CA A LYS A 1 117 ? -18.458 57.779 -84.350 0.50 21.48 ? 120 LYS A CA 1 ATOM 954 C CA B LYS A 1 117 ? -18.450 57.793 -84.363 0.50 21.48 ? 120 LYS A CA 1 ATOM 955 C C . LYS A 1 117 ? -19.511 57.571 -85.460 1.00 25.29 ? 120 LYS A C 1 ATOM 956 O O . LYS A 1 117 ? -20.208 56.544 -85.467 1.00 25.50 ? 120 LYS A O 1 ATOM 957 C CB A LYS A 1 117 ? -17.365 56.730 -84.511 0.50 21.85 ? 120 LYS A CB 1 ATOM 958 C CB B LYS A 1 117 ? -17.294 56.798 -84.578 0.50 21.85 ? 120 LYS A CB 1 ATOM 959 C CG A LYS A 1 117 ? -16.746 56.711 -85.872 0.50 22.73 ? 120 LYS A CG 1 ATOM 960 C CG B LYS A 1 117 ? -16.343 57.139 -85.762 0.50 20.56 ? 120 LYS A CG 1 ATOM 961 C CD A LYS A 1 117 ? -15.742 55.538 -85.992 0.50 27.62 ? 120 LYS A CD 1 ATOM 962 C CD B LYS A 1 117 ? -15.305 56.004 -86.027 0.50 22.58 ? 120 LYS A CD 1 ATOM 963 C CE A LYS A 1 117 ? -14.427 55.907 -85.378 0.50 29.94 ? 120 LYS A CE 1 ATOM 964 C CE B LYS A 1 117 ? -16.024 54.620 -86.239 0.50 17.00 ? 120 LYS A CE 1 ATOM 965 N NZ A LYS A 1 117 ? -13.365 54.832 -85.439 0.50 33.74 ? 120 LYS A NZ 1 ATOM 966 N NZ B LYS A 1 117 ? -15.121 53.449 -86.348 0.50 14.44 ? 120 LYS A NZ 1 ATOM 967 N N . ILE A 1 118 ? -19.646 58.521 -86.372 1.00 22.22 ? 121 ILE A N 1 ATOM 968 C CA . ILE A 1 118 ? -20.717 58.404 -87.369 1.00 22.91 ? 121 ILE A CA 1 ATOM 969 C C . ILE A 1 118 ? -20.118 58.561 -88.749 1.00 23.18 ? 121 ILE A C 1 ATOM 970 O O . ILE A 1 118 ? -19.145 59.267 -88.945 1.00 23.33 ? 121 ILE A O 1 ATOM 971 C CB . ILE A 1 118 ? -21.859 59.459 -87.178 1.00 23.41 ? 121 ILE A CB 1 ATOM 972 C CG1 . ILE A 1 118 ? -21.295 60.902 -87.254 1.00 25.62 ? 121 ILE A CG1 1 ATOM 973 C CG2 . ILE A 1 118 ? -22.647 59.163 -85.900 1.00 25.05 ? 121 ILE A CG2 1 ATOM 974 C CD1 . ILE A 1 118 ? -22.475 61.935 -87.465 1.00 24.51 ? 121 ILE A CD1 1 ATOM 975 N N . GLN A 1 119 ? -20.683 57.858 -89.747 1.00 21.29 ? 122 GLN A N 1 ATOM 976 C CA . GLN A 1 119 ? -20.192 58.071 -91.083 1.00 23.80 ? 122 GLN A CA 1 ATOM 977 C C . GLN A 1 119 ? -20.800 59.344 -91.650 1.00 26.50 ? 122 GLN A C 1 ATOM 978 O O . GLN A 1 119 ? -22.017 59.451 -91.680 1.00 30.57 ? 122 GLN A O 1 ATOM 979 C CB . GLN A 1 119 ? -20.637 56.886 -91.971 1.00 23.84 ? 122 GLN A CB 1 ATOM 980 C CG . GLN A 1 119 ? -19.888 56.767 -93.326 1.00 31.76 ? 122 GLN A CG 1 ATOM 981 C CD . GLN A 1 119 ? -20.538 55.640 -94.217 1.00 31.45 ? 122 GLN A CD 1 ATOM 982 O OE1 . GLN A 1 119 ? -21.756 55.582 -94.299 1.00 32.18 ? 122 GLN A OE1 1 ATOM 983 N NE2 . GLN A 1 119 ? -19.713 54.789 -94.858 1.00 27.29 ? 122 GLN A NE2 1 ATOM 984 N N . ILE A 1 120 ? -19.979 60.306 -92.085 1.00 21.77 ? 123 ILE A N 1 ATOM 985 C CA . ILE A 1 120 ? -20.496 61.527 -92.737 1.00 23.08 ? 123 ILE A CA 1 ATOM 986 C C . ILE A 1 120 ? -20.305 61.587 -94.242 1.00 26.81 ? 123 ILE A C 1 ATOM 987 O O . ILE A 1 120 ? -21.074 62.254 -94.930 1.00 29.97 ? 123 ILE A O 1 ATOM 988 C CB . ILE A 1 120 ? -19.970 62.850 -92.046 1.00 24.82 ? 123 ILE A CB 1 ATOM 989 C CG1 . ILE A 1 120 ? -18.479 62.927 -92.255 1.00 22.98 ? 123 ILE A CG1 1 ATOM 990 C CG2 . ILE A 1 120 ? -20.433 62.867 -90.540 1.00 22.65 ? 123 ILE A CG2 1 ATOM 991 C CD1 . ILE A 1 120 ? -17.857 64.365 -91.883 1.00 25.15 ? 123 ILE A CD1 1 ATOM 992 N N . ILE A 1 121 ? -19.297 60.901 -94.778 1.00 26.64 ? 124 ILE A N 1 ATOM 993 C CA . ILE A 1 121 ? -19.149 60.790 -96.253 1.00 24.54 ? 124 ILE A CA 1 ATOM 994 C C . ILE A 1 121 ? -18.737 59.351 -96.577 1.00 27.12 ? 124 ILE A C 1 ATOM 995 O O . ILE A 1 121 ? -17.625 58.903 -96.241 1.00 25.18 ? 124 ILE A O 1 ATOM 996 C CB . ILE A 1 121 ? -18.056 61.696 -96.813 1.00 24.96 ? 124 ILE A CB 1 ATOM 997 C CG1 . ILE A 1 121 ? -18.322 63.163 -96.461 1.00 26.81 ? 124 ILE A CG1 1 ATOM 998 C CG2 . ILE A 1 121 ? -17.970 61.541 -98.348 1.00 27.47 ? 124 ILE A CG2 1 ATOM 999 C CD1 . ILE A 1 121 ? -17.133 64.041 -96.892 1.00 28.92 ? 124 ILE A CD1 1 ATOM 1000 N N . PRO A 1 122 ? -19.651 58.574 -97.163 1.00 26.60 ? 125 PRO A N 1 ATOM 1001 C CA . PRO A 1 122 ? -19.303 57.152 -97.438 1.00 26.27 ? 125 PRO A CA 1 ATOM 1002 C C . PRO A 1 122 ? -18.125 57.013 -98.398 1.00 28.61 ? 125 PRO A C 1 ATOM 1003 O O . PRO A 1 122 ? -18.069 57.756 -99.380 1.00 29.28 ? 125 PRO A O 1 ATOM 1004 C CB . PRO A 1 122 ? -20.563 56.601 -98.131 1.00 26.19 ? 125 PRO A CB 1 ATOM 1005 C CG . PRO A 1 122 ? -21.700 57.496 -97.591 1.00 36.74 ? 125 PRO A CG 1 ATOM 1006 C CD . PRO A 1 122 ? -21.066 58.878 -97.411 1.00 30.36 ? 125 PRO A CD 1 ATOM 1007 N N . LYS A 1 123 A -17.200 56.097 -98.097 1.00 24.96 ? 125 LYS A N 1 ATOM 1008 C CA . LYS A 1 123 A -16.043 55.835 -98.912 1.00 26.20 ? 125 LYS A CA 1 ATOM 1009 C C . LYS A 1 123 A -16.518 55.355 -100.281 1.00 30.11 ? 125 LYS A C 1 ATOM 1010 O O . LYS A 1 123 A -15.826 55.531 -101.291 1.00 30.05 ? 125 LYS A O 1 ATOM 1011 C CB . LYS A 1 123 A -15.171 54.788 -98.247 1.00 31.99 ? 125 LYS A CB 1 ATOM 1012 C CG . LYS A 1 123 A -13.841 54.690 -98.848 1.00 30.29 ? 125 LYS A CG 1 ATOM 1013 C CD . LYS A 1 123 A -13.014 53.694 -98.054 1.00 31.94 ? 125 LYS A CD 1 ATOM 1014 C CE . LYS A 1 123 A -11.627 53.532 -98.603 1.00 38.52 ? 125 LYS A CE 1 ATOM 1015 N NZ . LYS A 1 123 A -10.914 52.502 -97.770 1.00 40.91 ? 125 LYS A NZ 1 ATOM 1016 N N . SER A 1 124 B -17.723 54.782 -100.305 1.00 26.62 ? 125 SER A N 1 ATOM 1017 C CA . SER A 1 124 B -18.255 54.239 -101.575 1.00 29.50 ? 125 SER A CA 1 ATOM 1018 C C . SER A 1 124 B -18.810 55.296 -102.513 1.00 37.11 ? 125 SER A C 1 ATOM 1019 O O . SER A 1 124 B -19.152 54.970 -103.652 1.00 32.17 ? 125 SER A O 1 ATOM 1020 C CB . SER A 1 124 B -19.378 53.240 -101.276 1.00 30.23 ? 125 SER A CB 1 ATOM 1021 O OG . SER A 1 124 B -20.450 53.902 -100.625 1.00 31.47 ? 125 SER A OG 1 ATOM 1022 N N . SER A 1 125 ? -18.883 56.548 -102.046 1.00 26.54 ? 126 SER A N 1 ATOM 1023 C CA . SER A 1 125 ? -19.566 57.619 -102.770 1.00 26.87 ? 126 SER A CA 1 ATOM 1024 C C . SER A 1 125 ? -18.679 58.453 -103.678 1.00 25.39 ? 126 SER A C 1 ATOM 1025 O O . SER A 1 125 ? -19.140 59.475 -104.198 1.00 35.83 ? 126 SER A O 1 ATOM 1026 C CB . SER A 1 125 ? -20.330 58.540 -101.808 1.00 31.43 ? 126 SER A CB 1 ATOM 1027 O OG . SER A 1 125 ? -19.430 59.404 -101.075 1.00 31.52 ? 126 SER A OG 1 ATOM 1028 N N . TRP A 1 126 ? -17.414 58.097 -103.784 1.00 26.44 ? 127 TRP A N 1 ATOM 1029 C CA . TRP A 1 126 ? -16.458 58.851 -104.590 1.00 30.58 ? 127 TRP A CA 1 ATOM 1030 C C . TRP A 1 126 ? -16.471 58.342 -106.039 1.00 30.51 ? 127 TRP A C 1 ATOM 1031 O O . TRP A 1 126 ? -15.582 57.614 -106.446 1.00 33.24 ? 127 TRP A O 1 ATOM 1032 C CB . TRP A 1 126 ? -15.065 58.721 -104.000 1.00 29.90 ? 127 TRP A CB 1 ATOM 1033 C CG . TRP A 1 126 ? -15.021 59.390 -102.624 1.00 28.02 ? 127 TRP A CG 1 ATOM 1034 C CD1 . TRP A 1 126 ? -14.996 58.760 -101.406 1.00 33.74 ? 127 TRP A CD1 1 ATOM 1035 C CD2 . TRP A 1 126 ? -15.043 60.809 -102.352 1.00 29.21 ? 127 TRP A CD2 1 ATOM 1036 N NE1 . TRP A 1 126 ? -15.005 59.720 -100.384 1.00 29.37 ? 127 TRP A NE1 1 ATOM 1037 C CE2 . TRP A 1 126 ? -14.998 60.965 -100.943 1.00 28.31 ? 127 TRP A CE2 1 ATOM 1038 C CE3 . TRP A 1 126 ? -15.066 61.956 -103.167 1.00 31.54 ? 127 TRP A CE3 1 ATOM 1039 C CZ2 . TRP A 1 126 ? -14.990 62.232 -100.326 1.00 29.93 ? 127 TRP A CZ2 1 ATOM 1040 C CZ3 . TRP A 1 126 ? -15.076 63.217 -102.561 1.00 32.01 ? 127 TRP A CZ3 1 ATOM 1041 C CH2 . TRP A 1 126 ? -15.029 63.338 -101.146 1.00 28.04 ? 127 TRP A CH2 1 ATOM 1042 N N . SER A 1 127 ? -17.475 58.743 -106.780 1.00 31.02 ? 128 SER A N 1 ATOM 1043 C CA . SER A 1 127 ? -17.674 58.085 -108.083 1.00 37.57 ? 128 SER A CA 1 ATOM 1044 C C . SER A 1 127 ? -16.726 58.580 -109.182 1.00 44.79 ? 128 SER A C 1 ATOM 1045 O O . SER A 1 127 ? -16.581 57.926 -110.228 1.00 40.38 ? 128 SER A O 1 ATOM 1046 C CB . SER A 1 127 ? -19.141 58.178 -108.478 1.00 36.22 ? 128 SER A CB 1 ATOM 1047 O OG . SER A 1 127 ? -19.581 59.517 -108.494 1.00 45.44 ? 128 SER A OG 1 ATOM 1048 N N . SER A 1 128 ? -16.030 59.690 -108.928 1.00 35.67 ? 129 SER A N 1 ATOM 1049 C CA . SER A 1 128 ? -15.111 60.266 -109.905 1.00 34.50 ? 129 SER A CA 1 ATOM 1050 C C . SER A 1 128 ? -13.636 60.246 -109.492 1.00 37.33 ? 129 SER A C 1 ATOM 1051 O O . SER A 1 128 ? -12.783 60.776 -110.227 1.00 31.10 ? 129 SER A O 1 ATOM 1052 C CB . SER A 1 128 ? -15.517 61.706 -110.238 1.00 40.99 ? 129 SER A CB 1 ATOM 1053 O OG . SER A 1 128 ? -16.825 61.759 -110.793 1.00 46.27 ? 129 SER A OG 1 ATOM 1054 N N . HIS A 1 129 ? -13.320 59.596 -108.364 1.00 33.39 ? 130 HIS A N 1 ATOM 1055 C CA . HIS A 1 129 ? -11.938 59.545 -107.871 1.00 37.50 ? 130 HIS A CA 1 ATOM 1056 C C . HIS A 1 129 ? -11.666 58.142 -107.420 1.00 28.78 ? 130 HIS A C 1 ATOM 1057 O O . HIS A 1 129 ? -12.619 57.390 -107.277 1.00 41.69 ? 130 HIS A O 1 ATOM 1058 C CB . HIS A 1 129 ? -11.783 60.536 -106.705 1.00 30.26 ? 130 HIS A CB 1 ATOM 1059 C CG . HIS A 1 129 ? -12.075 61.943 -107.106 1.00 27.53 ? 130 HIS A CG 1 ATOM 1060 N ND1 . HIS A 1 129 ? -13.347 62.428 -107.195 1.00 30.15 ? 130 HIS A ND1 1 ATOM 1061 C CD2 . HIS A 1 129 ? -11.248 62.968 -107.461 1.00 28.65 ? 130 HIS A CD2 1 ATOM 1062 C CE1 . HIS A 1 129 ? -13.311 63.689 -107.602 1.00 31.99 ? 130 HIS A CE1 1 ATOM 1063 N NE2 . HIS A 1 129 ? -12.049 64.033 -107.775 1.00 28.61 ? 130 HIS A NE2 1 ATOM 1064 N N . GLU A 1 130 ? -10.407 57.761 -107.244 1.00 29.98 ? 131 GLU A N 1 ATOM 1065 C CA . GLU A 1 130 ? -10.147 56.452 -106.669 1.00 29.28 ? 131 GLU A CA 1 ATOM 1066 C C . GLU A 1 130 ? -10.124 56.589 -105.162 1.00 34.56 ? 131 GLU A C 1 ATOM 1067 O O . GLU A 1 130 ? -9.397 57.424 -104.634 1.00 33.91 ? 131 GLU A O 1 ATOM 1068 C CB . GLU A 1 130 ? -8.828 55.875 -107.139 1.00 28.06 ? 131 GLU A CB 1 ATOM 1069 C CG . GLU A 1 130 ? -8.830 55.604 -108.674 1.00 33.48 ? 131 GLU A CG 1 ATOM 1070 C CD . GLU A 1 130 ? -9.624 54.326 -109.077 1.00 48.56 ? 131 GLU A CD 1 ATOM 1071 O OE1 . GLU A 1 130 ? -10.165 53.625 -108.188 1.00 46.15 ? 131 GLU A OE1 1 ATOM 1072 O OE2 . GLU A 1 130 ? -9.690 54.016 -110.297 1.00 48.55 ? 131 GLU A OE2 1 ATOM 1073 N N . ALA A 1 131 ? -10.889 55.746 -104.471 1.00 30.77 ? 132 ALA A N 1 ATOM 1074 C CA . ALA A 1 131 ? -10.919 55.848 -103.003 1.00 28.67 ? 132 ALA A CA 1 ATOM 1075 C C . ALA A 1 131 ? -10.200 54.706 -102.314 1.00 38.72 ? 132 ALA A C 1 ATOM 1076 O O . ALA A 1 131 ? -10.094 54.684 -101.098 1.00 30.23 ? 132 ALA A O 1 ATOM 1077 C CB . ALA A 1 131 ? -12.384 55.948 -102.517 1.00 30.68 ? 132 ALA A CB 1 ATOM 1078 N N . SER A 1 132 ? -9.693 53.734 -103.066 1.00 33.06 ? 133 SER A N 1 ATOM 1079 C CA . SER A 1 132 ? -9.106 52.584 -102.397 1.00 31.42 ? 133 SER A CA 1 ATOM 1080 C C . SER A 1 132 ? -7.660 52.371 -102.744 1.00 29.13 ? 133 SER A C 1 ATOM 1081 O O . SER A 1 132 ? -7.095 51.289 -102.483 1.00 36.31 ? 133 SER A O 1 ATOM 1082 C CB . SER A 1 132 ? -9.916 51.330 -102.685 1.00 44.95 ? 133 SER A CB 1 ATOM 1083 O OG . SER A 1 132 ? -9.881 51.113 -104.088 1.00 49.74 ? 133 SER A OG 1 ATOM 1084 N N . LEU A 1 133 A -7.035 53.395 -103.296 1.00 29.70 ? 133 LEU A N 1 ATOM 1085 C CA . LEU A 1 133 A -5.620 53.309 -103.606 1.00 27.23 ? 133 LEU A CA 1 ATOM 1086 C C . LEU A 1 133 A -4.722 54.121 -102.667 1.00 34.04 ? 133 LEU A C 1 ATOM 1087 O O . LEU A 1 133 A -3.489 54.164 -102.845 1.00 32.61 ? 133 LEU A O 1 ATOM 1088 C CB . LEU A 1 133 A -5.382 53.834 -105.007 1.00 32.29 ? 133 LEU A CB 1 ATOM 1089 C CG . LEU A 1 133 A -6.080 52.971 -106.067 1.00 41.17 ? 133 LEU A CG 1 ATOM 1090 C CD1 . LEU A 1 133 A -5.885 53.636 -107.409 1.00 42.81 ? 133 LEU A CD1 1 ATOM 1091 C CD2 . LEU A 1 133 A -5.490 51.550 -106.038 1.00 36.68 ? 133 LEU A CD2 1 ATOM 1092 N N . GLY A 1 134 ? -5.341 54.790 -101.705 1.00 34.47 ? 134 GLY A N 1 ATOM 1093 C CA . GLY A 1 134 ? -4.586 55.690 -100.841 1.00 30.22 ? 134 GLY A CA 1 ATOM 1094 C C . GLY A 1 134 ? -4.024 54.946 -99.665 1.00 32.74 ? 134 GLY A C 1 ATOM 1095 O O . GLY A 1 134 ? -4.471 55.164 -98.525 1.00 30.46 ? 134 GLY A O 1 ATOM 1096 N N . VAL A 1 135 ? -3.052 54.070 -99.919 1.00 28.28 ? 135 VAL A N 1 ATOM 1097 C CA . VAL A 1 135 ? -2.424 53.273 -98.858 1.00 25.58 ? 135 VAL A CA 1 ATOM 1098 C C . VAL A 1 135 ? -0.911 53.422 -98.903 1.00 25.98 ? 135 VAL A C 1 ATOM 1099 O O . VAL A 1 135 ? -0.356 53.915 -99.905 1.00 32.35 ? 135 VAL A O 1 ATOM 1100 C CB . VAL A 1 135 ? -2.778 51.759 -98.976 1.00 34.31 ? 135 VAL A CB 1 ATOM 1101 C CG1 . VAL A 1 135 ? -4.249 51.528 -98.739 1.00 35.57 ? 135 VAL A CG1 1 ATOM 1102 C CG2 . VAL A 1 135 ? -2.346 51.237 -100.375 1.00 31.67 ? 135 VAL A CG2 1 ATOM 1103 N N . SER A 1 136 ? -0.242 53.006 -97.824 1.00 25.38 ? 136 SER A N 1 ATOM 1104 C CA . SER A 1 136 ? 1.160 53.236 -97.718 1.00 29.99 ? 136 SER A CA 1 ATOM 1105 C C . SER A 1 136 ? 1.838 52.214 -96.826 1.00 28.92 ? 136 SER A C 1 ATOM 1106 O O . SER A 1 136 ? 1.301 51.771 -95.809 1.00 31.70 ? 136 SER A O 1 ATOM 1107 C CB . SER A 1 136 ? 1.419 54.692 -97.170 1.00 30.46 ? 136 SER A CB 1 ATOM 1108 O OG . SER A 1 136 ? 2.747 54.863 -96.764 1.00 31.50 ? 136 SER A OG 1 ATOM 1109 N N . SER A 1 137 ? 3.074 51.881 -97.194 1.00 29.17 ? 137 SER A N 1 ATOM 1110 C CA . SER A 1 137 ? 3.936 51.022 -96.391 1.00 32.01 ? 137 SER A CA 1 ATOM 1111 C C . SER A 1 137 ? 4.233 51.681 -95.022 1.00 36.57 ? 137 SER A C 1 ATOM 1112 O O . SER A 1 137 ? 4.630 51.016 -94.069 1.00 32.84 ? 137 SER A O 1 ATOM 1113 C CB . SER A 1 137 ? 5.261 50.735 -97.155 1.00 34.08 ? 137 SER A CB 1 ATOM 1114 O OG . SER A 1 137 ? 5.810 51.951 -97.655 1.00 42.27 ? 137 SER A OG 1 ATOM 1115 N N . ALA A 1 138 ? 3.986 52.980 -94.920 1.00 29.76 ? 138 ALA A N 1 ATOM 1116 C CA . ALA A 1 138 ? 4.220 53.665 -93.631 1.00 32.40 ? 138 ALA A CA 1 ATOM 1117 C C . ALA A 1 138 ? 3.148 53.236 -92.638 1.00 37.40 ? 138 ALA A C 1 ATOM 1118 O O . ALA A 1 138 ? 3.329 53.338 -91.404 1.00 33.94 ? 138 ALA A O 1 ATOM 1119 C CB . ALA A 1 138 ? 4.196 55.204 -93.851 1.00 32.70 ? 138 ALA A CB 1 ATOM 1120 N N . CYS A 1 139 ? 2.017 52.766 -93.177 1.00 30.60 ? 139 CYS A N 1 ATOM 1121 C CA . CYS A 1 139 ? 0.873 52.416 -92.349 1.00 26.09 ? 139 CYS A CA 1 ATOM 1122 C C . CYS A 1 139 ? 0.495 50.940 -92.498 1.00 29.98 ? 139 CYS A C 1 ATOM 1123 O O . CYS A 1 139 ? -0.590 50.638 -92.968 1.00 28.65 ? 139 CYS A O 1 ATOM 1124 C CB . CYS A 1 139 ? -0.324 53.274 -92.701 1.00 31.15 ? 139 CYS A CB 1 ATOM 1125 S SG . CYS A 1 139 ? -0.097 55.012 -92.147 1.00 44.15 ? 139 CYS A SG 1 ATOM 1126 N N . PRO A 1 140 ? 1.391 50.026 -92.101 1.00 35.43 ? 140 PRO A N 1 ATOM 1127 C CA . PRO A 1 140 ? 1.095 48.609 -92.356 1.00 34.80 ? 140 PRO A CA 1 ATOM 1128 C C . PRO A 1 140 ? 0.005 48.062 -91.463 1.00 35.50 ? 140 PRO A C 1 ATOM 1129 O O . PRO A 1 140 ? -0.152 48.501 -90.306 1.00 36.73 ? 140 PRO A O 1 ATOM 1130 C CB . PRO A 1 140 ? 2.431 47.924 -92.053 1.00 35.70 ? 140 PRO A CB 1 ATOM 1131 C CG . PRO A 1 140 ? 3.062 48.839 -90.980 1.00 42.40 ? 140 PRO A CG 1 ATOM 1132 C CD . PRO A 1 140 ? 2.729 50.213 -91.491 1.00 37.18 ? 140 PRO A CD 1 ATOM 1133 N N . TYR A 1 141 ? -0.781 47.133 -92.002 1.00 31.34 ? 141 TYR A N 1 ATOM 1134 C CA . TYR A 1 141 ? -1.717 46.390 -91.212 1.00 26.92 ? 141 TYR A CA 1 ATOM 1135 C C . TYR A 1 141 ? -1.727 44.908 -91.663 1.00 38.51 ? 141 TYR A C 1 ATOM 1136 O O . TYR A 1 141 ? -2.091 44.619 -92.809 1.00 36.78 ? 141 TYR A O 1 ATOM 1137 C CB . TYR A 1 141 ? -3.125 46.960 -91.393 1.00 31.96 ? 141 TYR A CB 1 ATOM 1138 C CG . TYR A 1 141 ? -4.159 46.212 -90.581 1.00 36.90 ? 141 TYR A CG 1 ATOM 1139 C CD1 . TYR A 1 141 ? -4.157 46.226 -89.177 1.00 37.99 ? 141 TYR A CD1 1 ATOM 1140 C CD2 . TYR A 1 141 ? -5.139 45.468 -91.223 1.00 39.20 ? 141 TYR A CD2 1 ATOM 1141 C CE1 . TYR A 1 141 ? -5.140 45.507 -88.455 1.00 33.63 ? 141 TYR A CE1 1 ATOM 1142 C CE2 . TYR A 1 141 ? -6.094 44.781 -90.520 1.00 42.01 ? 141 TYR A CE2 1 ATOM 1143 C CZ . TYR A 1 141 ? -6.098 44.798 -89.154 1.00 44.25 ? 141 TYR A CZ 1 ATOM 1144 O OH . TYR A 1 141 ? -7.084 44.054 -88.531 1.00 44.21 ? 141 TYR A OH 1 ATOM 1145 N N . GLN A 1 142 ? -1.345 44.004 -90.763 1.00 35.62 ? 142 GLN A N 1 ATOM 1146 C CA . GLN A 1 142 ? -1.395 42.564 -91.067 1.00 43.42 ? 142 GLN A CA 1 ATOM 1147 C C . GLN A 1 142 ? -0.664 42.277 -92.380 1.00 43.81 ? 142 GLN A C 1 ATOM 1148 O O . GLN A 1 142 ? -1.216 41.668 -93.308 1.00 45.43 ? 142 GLN A O 1 ATOM 1149 C CB . GLN A 1 142 ? -2.853 42.096 -91.128 1.00 36.53 ? 142 GLN A CB 1 ATOM 1150 C CG . GLN A 1 142 ? -3.434 41.948 -89.726 1.00 45.23 ? 142 GLN A CG 1 ATOM 1151 C CD . GLN A 1 142 ? -4.890 41.501 -89.681 1.00 55.99 ? 142 GLN A CD 1 ATOM 1152 O OE1 . GLN A 1 142 ? -5.542 41.320 -90.711 1.00 50.61 ? 142 GLN A OE1 1 ATOM 1153 N NE2 . GLN A 1 142 ? -5.405 41.327 -88.467 1.00 52.05 ? 142 GLN A NE2 1 ATOM 1154 N N . GLY A 1 143 ? 0.552 42.801 -92.473 1.00 38.49 ? 143 GLY A N 1 ATOM 1155 C CA . GLY A 1 143 ? 1.388 42.624 -93.648 1.00 43.21 ? 143 GLY A CA 1 ATOM 1156 C C . GLY A 1 143 ? 1.046 43.322 -94.951 1.00 55.47 ? 143 GLY A C 1 ATOM 1157 O O . GLY A 1 143 ? 1.672 43.054 -95.998 1.00 45.82 ? 143 GLY A O 1 ATOM 1158 N N . LYS A 1 144 ? 0.070 44.225 -94.922 1.00 42.45 ? 144 LYS A N 1 ATOM 1159 C CA . LYS A 1 144 ? -0.275 44.944 -96.134 1.00 37.66 ? 144 LYS A CA 1 ATOM 1160 C C . LYS A 1 144 ? -0.232 46.462 -95.906 1.00 36.89 ? 144 LYS A C 1 ATOM 1161 O O . LYS A 1 144 ? -0.586 46.925 -94.824 1.00 37.16 ? 144 LYS A O 1 ATOM 1162 C CB . LYS A 1 144 ? -1.683 44.571 -96.579 1.00 44.75 ? 144 LYS A CB 1 ATOM 1163 C CG . LYS A 1 144 ? -1.930 43.055 -96.702 1.00 55.29 ? 144 LYS A CG 1 ATOM 1164 C CD . LYS A 1 144 ? -3.378 42.792 -97.140 1.00 61.57 ? 144 LYS A CD 1 ATOM 1165 C CE . LYS A 1 144 ? -3.635 41.314 -97.470 1.00 103.07 ? 144 LYS A CE 1 ATOM 1166 N NZ . LYS A 1 144 ? -5.001 41.102 -98.047 1.00 88.65 ? 144 LYS A NZ 1 ATOM 1167 N N . SER A 1 145 ? 0.121 47.220 -96.932 1.00 34.45 ? 145 SER A N 1 ATOM 1168 C CA . SER A 1 145 ? -0.080 48.698 -96.869 1.00 32.20 ? 145 SER A CA 1 ATOM 1169 C C . SER A 1 145 ? -1.523 49.123 -96.535 1.00 36.05 ? 145 SER A C 1 ATOM 1170 O O . SER A 1 145 ? -2.531 48.612 -97.090 1.00 30.59 ? 145 SER A O 1 ATOM 1171 C CB . SER A 1 145 ? 0.346 49.337 -98.180 1.00 31.80 ? 145 SER A CB 1 ATOM 1172 O OG . SER A 1 145 ? 1.709 49.080 -98.443 1.00 39.15 ? 145 SER A OG 1 ATOM 1173 N N . SER A 1 146 ? -1.646 50.131 -95.653 1.00 29.55 ? 146 SER A N 1 ATOM 1174 C CA . SER A 1 146 ? -2.976 50.557 -95.219 1.00 25.89 ? 146 SER A CA 1 ATOM 1175 C C . SER A 1 146 ? -2.905 52.075 -94.970 1.00 28.27 ? 146 SER A C 1 ATOM 1176 O O . SER A 1 146 ? -2.074 52.715 -95.538 1.00 25.85 ? 146 SER A O 1 ATOM 1177 C CB . SER A 1 146 ? -3.401 49.823 -93.949 1.00 32.70 ? 146 SER A CB 1 ATOM 1178 O OG . SER A 1 146 ? -4.796 50.070 -93.687 1.00 28.24 ? 146 SER A OG 1 ATOM 1179 N N . PHE A 1 147 ? -3.811 52.607 -94.155 1.00 25.68 ? 147 PHE A N 1 ATOM 1180 C CA . PHE A 1 147 ? -3.824 54.067 -93.945 1.00 25.78 ? 147 PHE A CA 1 ATOM 1181 C C . PHE A 1 147 ? -4.740 54.354 -92.782 1.00 23.31 ? 147 PHE A C 1 ATOM 1182 O O . PHE A 1 147 ? -5.494 53.495 -92.334 1.00 25.14 ? 147 PHE A O 1 ATOM 1183 C CB . PHE A 1 147 ? -4.415 54.800 -95.145 1.00 28.26 ? 147 PHE A CB 1 ATOM 1184 C CG . PHE A 1 147 ? -4.078 56.293 -95.175 1.00 27.68 ? 147 PHE A CG 1 ATOM 1185 C CD1 . PHE A 1 147 ? -2.763 56.711 -95.261 1.00 27.36 ? 147 PHE A CD1 1 ATOM 1186 C CD2 . PHE A 1 147 ? -5.082 57.259 -95.099 1.00 27.62 ? 147 PHE A CD2 1 ATOM 1187 C CE1 . PHE A 1 147 ? -2.429 58.080 -95.319 1.00 29.67 ? 147 PHE A CE1 1 ATOM 1188 C CE2 . PHE A 1 147 ? -4.734 58.645 -95.155 1.00 26.27 ? 147 PHE A CE2 1 ATOM 1189 C CZ . PHE A 1 147 ? -3.415 59.022 -95.292 1.00 26.00 ? 147 PHE A CZ 1 ATOM 1190 N N . PHE A 1 148 ? -4.678 55.598 -92.282 1.00 23.56 ? 148 PHE A N 1 ATOM 1191 C CA . PHE A 1 148 ? -5.656 56.005 -91.261 1.00 22.15 ? 148 PHE A CA 1 ATOM 1192 C C . PHE A 1 148 ? -7.070 55.642 -91.678 1.00 25.69 ? 148 PHE A C 1 ATOM 1193 O O . PHE A 1 148 ? -7.493 56.002 -92.757 1.00 26.25 ? 148 PHE A O 1 ATOM 1194 C CB . PHE A 1 148 ? -5.564 57.545 -91.111 1.00 19.61 ? 148 PHE A CB 1 ATOM 1195 C CG . PHE A 1 148 ? -4.157 58.037 -90.706 1.00 25.22 ? 148 PHE A CG 1 ATOM 1196 C CD1 . PHE A 1 148 ? -3.326 58.683 -91.625 1.00 25.29 ? 148 PHE A CD1 1 ATOM 1197 C CD2 . PHE A 1 148 ? -3.706 57.873 -89.376 1.00 24.69 ? 148 PHE A CD2 1 ATOM 1198 C CE1 . PHE A 1 148 ? -2.040 59.160 -91.238 1.00 27.15 ? 148 PHE A CE1 1 ATOM 1199 C CE2 . PHE A 1 148 ? -2.473 58.340 -88.986 1.00 26.78 ? 148 PHE A CE2 1 ATOM 1200 C CZ . PHE A 1 148 ? -1.610 59.000 -89.923 1.00 24.84 ? 148 PHE A CZ 1 ATOM 1201 N N . ARG A 1 149 ? -7.818 55.012 -90.782 1.00 21.52 ? 149 ARG A N 1 ATOM 1202 C CA . ARG A 1 149 ? -9.153 54.487 -91.130 1.00 22.05 ? 149 ARG A CA 1 ATOM 1203 C C . ARG A 1 149 ? -10.282 55.522 -91.231 1.00 24.13 ? 149 ARG A C 1 ATOM 1204 O O . ARG A 1 149 ? -11.322 55.277 -91.847 1.00 26.50 ? 149 ARG A O 1 ATOM 1205 C CB . ARG A 1 149 ? -9.536 53.378 -90.152 1.00 23.15 ? 149 ARG A CB 1 ATOM 1206 C CG . ARG A 1 149 ? -8.551 52.191 -90.177 1.00 31.56 ? 149 ARG A CG 1 ATOM 1207 C CD . ARG A 1 149 ? -9.194 50.947 -89.552 1.00 30.12 ? 149 ARG A CD 1 ATOM 1208 N NE . ARG A 1 149 ? -8.250 49.823 -89.395 1.00 30.43 ? 149 ARG A NE 1 ATOM 1209 C CZ . ARG A 1 149 ? -7.801 49.011 -90.366 1.00 37.19 ? 149 ARG A CZ 1 ATOM 1210 N NH1 . ARG A 1 149 ? -8.175 49.146 -91.652 1.00 31.42 ? 149 ARG A NH1 1 ATOM 1211 N NH2 . ARG A 1 149 ? -6.959 48.030 -90.028 1.00 39.07 ? 149 ARG A NH2 1 ATOM 1212 N N . ASN A 1 150 ? -10.157 56.662 -90.541 1.00 21.51 ? 150 ASN A N 1 ATOM 1213 C CA . ASN A 1 150 ? -11.309 57.560 -90.460 1.00 22.63 ? 150 ASN A CA 1 ATOM 1214 C C . ASN A 1 150 ? -11.329 58.647 -91.539 1.00 22.30 ? 150 ASN A C 1 ATOM 1215 O O . ASN A 1 150 ? -12.325 59.411 -91.642 1.00 24.28 ? 150 ASN A O 1 ATOM 1216 C CB . ASN A 1 150 ? -11.308 58.192 -89.059 1.00 21.84 ? 150 ASN A CB 1 ATOM 1217 C CG . ASN A 1 150 ? -11.670 57.165 -87.999 1.00 27.09 ? 150 ASN A CG 1 ATOM 1218 O OD1 . ASN A 1 150 ? -12.439 56.253 -88.288 1.00 25.30 ? 150 ASN A OD1 1 ATOM 1219 N ND2 . ASN A 1 150 ? -11.172 57.327 -86.759 1.00 29.56 ? 150 ASN A ND2 1 ATOM 1220 N N . VAL A 1 151 ? -10.241 58.686 -92.328 1.00 22.64 ? 151 VAL A N 1 ATOM 1221 C CA . VAL A 1 151 ? -10.139 59.609 -93.458 1.00 22.18 ? 151 VAL A CA 1 ATOM 1222 C C . VAL A 1 151 ? -9.718 58.840 -94.714 1.00 23.48 ? 151 VAL A C 1 ATOM 1223 O O . VAL A 1 151 ? -9.225 57.712 -94.599 1.00 28.84 ? 151 VAL A O 1 ATOM 1224 C CB . VAL A 1 151 ? -9.116 60.738 -93.210 1.00 23.66 ? 151 VAL A CB 1 ATOM 1225 C CG1 . VAL A 1 151 ? -9.681 61.633 -92.104 1.00 27.97 ? 151 VAL A CG1 1 ATOM 1226 C CG2 . VAL A 1 151 ? -7.781 60.177 -92.787 1.00 23.06 ? 151 VAL A CG2 1 ATOM 1227 N N . VAL A 1 152 ? -9.950 59.434 -95.878 1.00 22.51 ? 152 VAL A N 1 ATOM 1228 C CA . VAL A 1 152 ? -9.724 58.675 -97.150 1.00 24.05 ? 152 VAL A CA 1 ATOM 1229 C C . VAL A 1 152 ? -8.751 59.447 -98.060 1.00 22.19 ? 152 VAL A C 1 ATOM 1230 O O . VAL A 1 152 ? -9.055 60.596 -98.433 1.00 25.80 ? 152 VAL A O 1 ATOM 1231 C CB . VAL A 1 152 ? -11.048 58.560 -97.877 1.00 22.92 ? 152 VAL A CB 1 ATOM 1232 C CG1 . VAL A 1 152 ? -10.781 57.813 -99.261 1.00 22.80 ? 152 VAL A CG1 1 ATOM 1233 C CG2 . VAL A 1 152 ? -12.040 57.782 -97.018 1.00 26.85 ? 152 VAL A CG2 1 ATOM 1234 N N . TRP A 1 153 ? -7.599 58.847 -98.370 1.00 23.32 ? 153 TRP A N 1 ATOM 1235 C CA . TRP A 1 153 ? -6.576 59.450 -99.239 1.00 23.76 ? 153 TRP A CA 1 ATOM 1236 C C . TRP A 1 153 ? -7.051 59.223 -100.683 1.00 28.63 ? 153 TRP A C 1 ATOM 1237 O O . TRP A 1 153 ? -6.857 58.127 -101.252 1.00 29.27 ? 153 TRP A O 1 ATOM 1238 C CB . TRP A 1 153 ? -5.254 58.778 -98.995 1.00 25.38 ? 153 TRP A CB 1 ATOM 1239 C CG . TRP A 1 153 ? -4.079 59.344 -99.780 1.00 28.29 ? 153 TRP A CG 1 ATOM 1240 C CD1 . TRP A 1 153 ? -4.085 60.372 -100.688 1.00 27.21 ? 153 TRP A CD1 1 ATOM 1241 C CD2 . TRP A 1 153 ? -2.731 58.914 -99.665 1.00 25.52 ? 153 TRP A CD2 1 ATOM 1242 N NE1 . TRP A 1 153 ? -2.808 60.581 -101.158 1.00 30.75 ? 153 TRP A NE1 1 ATOM 1243 C CE2 . TRP A 1 153 ? -1.959 59.712 -100.523 1.00 27.54 ? 153 TRP A CE2 1 ATOM 1244 C CE3 . TRP A 1 153 ? -2.093 57.925 -98.887 1.00 27.50 ? 153 TRP A CE3 1 ATOM 1245 C CZ2 . TRP A 1 153 ? -0.590 59.539 -100.656 1.00 30.33 ? 153 TRP A CZ2 1 ATOM 1246 C CZ3 . TRP A 1 153 ? -0.737 57.768 -99.021 1.00 31.06 ? 153 TRP A CZ3 1 ATOM 1247 C CH2 . TRP A 1 153 ? -0.004 58.556 -99.913 1.00 28.17 ? 153 TRP A CH2 1 ATOM 1248 N N . LEU A 1 154 ? -7.695 60.232 -101.237 1.00 23.07 ? 154 LEU A N 1 ATOM 1249 C CA . LEU A 1 154 ? -8.271 60.153 -102.622 1.00 26.17 ? 154 LEU A CA 1 ATOM 1250 C C . LEU A 1 154 ? -7.188 60.286 -103.682 1.00 31.51 ? 154 LEU A C 1 ATOM 1251 O O . LEU A 1 154 ? -6.247 61.063 -103.528 1.00 27.94 ? 154 LEU A O 1 ATOM 1252 C CB . LEU A 1 154 ? -9.367 61.201 -102.861 1.00 26.06 ? 154 LEU A CB 1 ATOM 1253 C CG . LEU A 1 154 ? -10.587 61.057 -101.925 1.00 27.45 ? 154 LEU A CG 1 ATOM 1254 C CD1 . LEU A 1 154 ? -11.467 62.254 -102.040 1.00 25.48 ? 154 LEU A CD1 1 ATOM 1255 C CD2 . LEU A 1 154 ? -11.386 59.796 -102.311 1.00 24.21 ? 154 LEU A CD2 1 ATOM 1256 N N . ILE A 1 155 ? -7.312 59.510 -104.770 1.00 26.66 ? 155 ILE A N 1 ATOM 1257 C CA . ILE A 1 155 ? -6.274 59.459 -105.784 1.00 30.19 ? 155 ILE A CA 1 ATOM 1258 C C . ILE A 1 155 ? -6.997 59.672 -107.118 1.00 27.79 ? 155 ILE A C 1 ATOM 1259 O O . ILE A 1 155 ? -8.190 59.461 -107.194 1.00 29.10 ? 155 ILE A O 1 ATOM 1260 C CB . ILE A 1 155 ? -5.579 58.071 -105.727 1.00 34.49 ? 155 ILE A CB 1 ATOM 1261 C CG1 . ILE A 1 155 ? -4.746 57.988 -104.441 1.00 36.46 ? 155 ILE A CG1 1 ATOM 1262 C CG2 . ILE A 1 155 ? -4.685 57.836 -106.945 1.00 38.28 ? 155 ILE A CG2 1 ATOM 1263 C CD1 . ILE A 1 155 ? -3.664 59.045 -104.438 1.00 35.44 ? 155 ILE A CD1 1 ATOM 1264 N N . LYS A 1 156 ? -6.299 60.246 -108.102 1.00 28.58 ? 156 LYS A N 1 ATOM 1265 C CA . LYS A 1 156 ? -6.929 60.547 -109.389 1.00 33.58 ? 156 LYS A CA 1 ATOM 1266 C C . LYS A 1 156 ? -7.427 59.233 -109.995 1.00 31.31 ? 156 LYS A C 1 ATOM 1267 O O . LYS A 1 156 ? -6.930 58.133 -109.653 1.00 31.11 ? 156 LYS A O 1 ATOM 1268 C CB . LYS A 1 156 ? -5.921 61.197 -110.345 1.00 34.98 ? 156 LYS A CB 1 ATOM 1269 C CG . LYS A 1 156 ? -4.890 60.191 -110.834 1.00 37.10 ? 156 LYS A CG 1 ATOM 1270 C CD . LYS A 1 156 ? -3.887 60.845 -111.781 1.00 40.31 ? 156 LYS A CD 1 ATOM 1271 C CE . LYS A 1 156 ? -2.833 59.833 -112.230 1.00 44.77 ? 156 LYS A CE 1 ATOM 1272 N NZ . LYS A 1 156 ? -1.723 60.480 -112.995 1.00 39.39 ? 156 LYS A NZ 1 ATOM 1273 N N . LYS A 1 157 ? -8.381 59.363 -110.913 1.00 34.02 ? 157 LYS A N 1 ATOM 1274 C CA . LYS A 1 157 ? -9.000 58.211 -111.571 1.00 39.33 ? 157 LYS A CA 1 ATOM 1275 C C . LYS A 1 157 ? -8.919 58.423 -113.094 1.00 39.79 ? 157 LYS A C 1 ATOM 1276 O O . LYS A 1 157 ? -9.332 59.477 -113.609 1.00 38.07 ? 157 LYS A O 1 ATOM 1277 C CB . LYS A 1 157 ? -10.459 58.101 -111.127 1.00 36.39 ? 157 LYS A CB 1 ATOM 1278 C CG . LYS A 1 157 ? -11.230 56.982 -111.757 1.00 41.30 ? 157 LYS A CG 1 ATOM 1279 C CD . LYS A 1 157 ? -12.722 57.091 -111.441 1.00 38.27 ? 157 LYS A CD 1 ATOM 1280 C CE . LYS A 1 157 ? -13.458 55.788 -111.727 1.00 39.19 ? 157 LYS A CE 1 ATOM 1281 N NZ . LYS A 1 157 ? -14.934 56.025 -111.575 1.00 40.17 ? 157 LYS A NZ 1 ATOM 1282 N N . ASN A 1 158 ? -8.383 57.419 -113.788 1.00 43.82 ? 158 ASN A N 1 ATOM 1283 C CA . ASN A 1 158 ? -8.248 57.482 -115.251 1.00 46.14 ? 158 ASN A CA 1 ATOM 1284 C C . ASN A 1 158 ? -7.525 58.758 -115.649 1.00 45.18 ? 158 ASN A C 1 ATOM 1285 O O . ASN A 1 158 ? -8.021 59.539 -116.460 1.00 40.22 ? 158 ASN A O 1 ATOM 1286 C CB . ASN A 1 158 ? -9.633 57.413 -115.913 1.00 43.96 ? 158 ASN A CB 1 ATOM 1287 C CG . ASN A 1 158 ? -9.584 56.829 -117.342 1.00 77.78 ? 158 ASN A CG 1 ATOM 1288 O OD1 . ASN A 1 158 ? -8.562 56.273 -117.764 1.00 82.37 ? 158 ASN A OD1 1 ATOM 1289 N ND2 . ASN A 1 158 ? -10.696 56.952 -118.082 1.00 84.81 ? 158 ASN A ND2 1 ATOM 1290 N N . SER A 1 159 ? -6.376 58.985 -115.030 1.00 37.62 ? 159 SER A N 1 ATOM 1291 C CA . SER A 1 159 ? -5.612 60.212 -115.226 1.00 41.40 ? 159 SER A CA 1 ATOM 1292 C C . SER A 1 159 ? -6.380 61.540 -115.076 1.00 42.41 ? 159 SER A C 1 ATOM 1293 O O . SER A 1 159 ? -5.955 62.550 -115.633 1.00 46.30 ? 159 SER A O 1 ATOM 1294 C CB . SER A 1 159 ? -4.903 60.159 -116.596 1.00 42.22 ? 159 SER A CB 1 ATOM 1295 O OG . SER A 1 159 ? -4.068 59.015 -116.676 1.00 45.84 ? 159 SER A OG 1 ATOM 1296 N N . THR A 1 160 ? -7.496 61.566 -114.343 1.00 39.92 ? 160 THR A N 1 ATOM 1297 C CA . THR A 1 160 ? -8.189 62.832 -114.116 1.00 35.97 ? 160 THR A CA 1 ATOM 1298 C C . THR A 1 160 ? -8.505 62.998 -112.620 1.00 40.41 ? 160 THR A C 1 ATOM 1299 O O . THR A 1 160 ? -8.778 62.004 -111.938 1.00 38.26 ? 160 THR A O 1 ATOM 1300 C CB . THR A 1 160 ? -9.530 62.954 -114.887 1.00 45.09 ? 160 THR A CB 1 ATOM 1301 O OG1 . THR A 1 160 ? -10.576 62.276 -114.186 1.00 53.39 ? 160 THR A OG1 1 ATOM 1302 C CG2 . THR A 1 160 ? -9.424 62.349 -116.231 1.00 46.56 ? 160 THR A CG2 1 ATOM 1303 N N . TYR A 1 161 ? -8.512 64.242 -112.132 1.00 36.12 ? 161 TYR A N 1 ATOM 1304 C CA . TYR A 1 161 ? -9.007 64.487 -110.755 1.00 35.09 ? 161 TYR A CA 1 ATOM 1305 C C . TYR A 1 161 ? -9.929 65.672 -110.837 1.00 31.97 ? 161 TYR A C 1 ATOM 1306 O O . TYR A 1 161 ? -9.485 66.821 -110.767 1.00 37.01 ? 161 TYR A O 1 ATOM 1307 C CB . TYR A 1 161 ? -7.826 64.737 -109.831 1.00 34.07 ? 161 TYR A CB 1 ATOM 1308 C CG . TYR A 1 161 ? -8.104 64.772 -108.324 1.00 32.53 ? 161 TYR A CG 1 ATOM 1309 C CD1 . TYR A 1 161 ? -7.522 63.827 -107.487 1.00 33.68 ? 161 TYR A CD1 1 ATOM 1310 C CD2 . TYR A 1 161 ? -8.883 65.804 -107.747 1.00 33.82 ? 161 TYR A CD2 1 ATOM 1311 C CE1 . TYR A 1 161 ? -7.724 63.875 -106.078 1.00 32.31 ? 161 TYR A CE1 1 ATOM 1312 C CE2 . TYR A 1 161 ? -9.082 65.860 -106.360 1.00 35.19 ? 161 TYR A CE2 1 ATOM 1313 C CZ . TYR A 1 161 ? -8.492 64.892 -105.544 1.00 30.98 ? 161 TYR A CZ 1 ATOM 1314 O OH . TYR A 1 161 ? -8.665 64.937 -104.172 1.00 32.81 ? 161 TYR A OH 1 ATOM 1315 N N . PRO A 1 162 ? -11.217 65.403 -111.058 1.00 31.41 ? 162 PRO A N 1 ATOM 1316 C CA . PRO A 1 162 ? -12.248 66.428 -111.217 1.00 34.13 ? 162 PRO A CA 1 ATOM 1317 C C . PRO A 1 162 ? -12.356 67.223 -109.923 1.00 39.75 ? 162 PRO A C 1 ATOM 1318 O O . PRO A 1 162 ? -12.051 66.679 -108.863 1.00 33.63 ? 162 PRO A O 1 ATOM 1319 C CB . PRO A 1 162 ? -13.528 65.617 -111.363 1.00 34.03 ? 162 PRO A CB 1 ATOM 1320 C CG . PRO A 1 162 ? -13.079 64.319 -111.936 1.00 40.87 ? 162 PRO A CG 1 ATOM 1321 C CD . PRO A 1 162 ? -11.738 64.046 -111.324 1.00 40.81 ? 162 PRO A CD 1 ATOM 1322 N N . THR A 1 163 ? -12.829 68.452 -109.991 1.00 35.52 ? 163 THR A N 1 ATOM 1323 C CA . THR A 1 163 ? -12.955 69.233 -108.754 1.00 35.16 ? 163 THR A CA 1 ATOM 1324 C C . THR A 1 163 ? -14.024 68.639 -107.830 1.00 35.35 ? 163 THR A C 1 ATOM 1325 O O . THR A 1 163 ? -15.154 68.442 -108.231 1.00 40.13 ? 163 THR A O 1 ATOM 1326 C CB . THR A 1 163 ? -13.274 70.677 -109.078 1.00 40.37 ? 163 THR A CB 1 ATOM 1327 O OG1 . THR A 1 163 ? -12.138 71.241 -109.745 1.00 41.24 ? 163 THR A OG1 1 ATOM 1328 C CG2 . THR A 1 163 ? -13.566 71.458 -107.808 1.00 43.54 ? 163 THR A CG2 1 ATOM 1329 N N . ILE A 1 164 ? -13.639 68.324 -106.597 1.00 29.23 ? 164 ILE A N 1 ATOM 1330 C CA . ILE A 1 164 ? -14.592 67.857 -105.583 1.00 28.89 ? 164 ILE A CA 1 ATOM 1331 C C . ILE A 1 164 ? -15.352 69.008 -104.953 1.00 37.05 ? 164 ILE A C 1 ATOM 1332 O O . ILE A 1 164 ? -14.754 70.013 -104.607 1.00 33.34 ? 164 ILE A O 1 ATOM 1333 C CB . ILE A 1 164 ? -13.842 67.130 -104.462 1.00 28.71 ? 164 ILE A CB 1 ATOM 1334 C CG1 . ILE A 1 164 ? -13.259 65.811 -104.991 1.00 27.71 ? 164 ILE A CG1 1 ATOM 1335 C CG2 . ILE A 1 164 ? -14.738 66.888 -103.239 1.00 28.38 ? 164 ILE A CG2 1 ATOM 1336 C CD1 . ILE A 1 164 ? -12.218 65.153 -104.164 1.00 28.40 ? 164 ILE A CD1 1 ATOM 1337 N N . LYS A 1 165 ? -16.666 68.857 -104.815 1.00 31.85 ? 165 LYS A N 1 ATOM 1338 C CA . LYS A 1 165 ? -17.530 69.776 -104.026 1.00 35.72 ? 165 LYS A CA 1 ATOM 1339 C C . LYS A 1 165 ? -18.481 68.935 -103.205 1.00 40.95 ? 165 LYS A C 1 ATOM 1340 O O . LYS A 1 165 ? -19.417 68.358 -103.749 1.00 37.61 ? 165 LYS A O 1 ATOM 1341 C CB . LYS A 1 165 ? -18.361 70.705 -104.929 1.00 38.74 ? 165 LYS A CB 1 ATOM 1342 C CG . LYS A 1 165 ? -17.493 71.533 -105.838 1.00 39.94 ? 165 LYS A CG 1 ATOM 1343 C CD . LYS A 1 165 ? -18.322 72.541 -106.661 1.00 43.49 ? 165 LYS A CD 1 ATOM 1344 C CE . LYS A 1 165 ? -17.407 73.438 -107.493 1.00 52.37 ? 165 LYS A CE 1 ATOM 1345 N NZ . LYS A 1 165 ? -18.180 74.365 -108.393 1.00 55.38 ? 165 LYS A NZ 1 ATOM 1346 N N . ARG A 1 166 ? -18.236 68.816 -101.897 1.00 31.20 ? 166 ARG A N 1 ATOM 1347 C CA . ARG A 1 166 ? -19.082 67.974 -101.073 1.00 30.63 ? 166 ARG A CA 1 ATOM 1348 C C . ARG A 1 166 ? -19.396 68.733 -99.802 1.00 32.76 ? 166 ARG A C 1 ATOM 1349 O O . ARG A 1 166 ? -18.525 69.430 -99.243 1.00 31.78 ? 166 ARG A O 1 ATOM 1350 C CB . ARG A 1 166 ? -18.406 66.668 -100.652 1.00 31.28 ? 166 ARG A CB 1 ATOM 1351 C CG . ARG A 1 166 ? -17.756 65.786 -101.723 1.00 44.17 ? 166 ARG A CG 1 ATOM 1352 C CD . ARG A 1 166 ? -18.737 64.928 -102.535 1.00 44.95 ? 166 ARG A CD 1 ATOM 1353 N NE . ARG A 1 166 ? -19.609 64.057 -101.742 1.00 48.65 ? 166 ARG A NE 1 ATOM 1354 C CZ . ARG A 1 166 ? -19.472 62.728 -101.649 1.00 37.05 ? 166 ARG A CZ 1 ATOM 1355 N NH1 . ARG A 1 166 ? -18.470 62.114 -102.251 1.00 34.19 ? 166 ARG A NH1 1 ATOM 1356 N NH2 . ARG A 1 166 ? -20.338 62.021 -100.957 1.00 38.61 ? 166 ARG A NH2 1 ATOM 1357 N N . SER A 1 167 ? -20.612 68.557 -99.330 1.00 27.36 ? 167 SER A N 1 ATOM 1358 C CA . SER A 1 167 ? -21.095 69.205 -98.105 1.00 31.06 ? 167 SER A CA 1 ATOM 1359 C C . SER A 1 167 ? -21.656 68.178 -97.192 1.00 38.69 ? 167 SER A C 1 ATOM 1360 O O . SER A 1 167 ? -22.151 67.144 -97.647 1.00 33.74 ? 167 SER A O 1 ATOM 1361 C CB . SER A 1 167 ? -22.235 70.180 -98.375 1.00 33.22 ? 167 SER A CB 1 ATOM 1362 O OG . SER A 1 167 ? -21.831 71.202 -99.248 1.00 47.87 ? 167 SER A OG 1 ATOM 1363 N N . TYR A 1 168 ? -21.624 68.485 -95.895 1.00 31.84 ? 168 TYR A N 1 ATOM 1364 C CA . TYR A 1 168 ? -22.310 67.694 -94.899 1.00 25.92 ? 168 TYR A CA 1 ATOM 1365 C C . TYR A 1 168 ? -22.981 68.643 -93.896 1.00 31.36 ? 168 TYR A C 1 ATOM 1366 O O . TYR A 1 168 ? -22.326 69.510 -93.311 1.00 28.92 ? 168 TYR A O 1 ATOM 1367 C CB . TYR A 1 168 ? -21.374 66.681 -94.189 1.00 25.84 ? 168 TYR A CB 1 ATOM 1368 C CG . TYR A 1 168 ? -22.033 66.118 -92.950 1.00 31.31 ? 168 TYR A CG 1 ATOM 1369 C CD1 . TYR A 1 168 ? -22.854 64.994 -93.033 1.00 29.49 ? 168 TYR A CD1 1 ATOM 1370 C CD2 . TYR A 1 168 ? -21.905 66.755 -91.698 1.00 25.81 ? 168 TYR A CD2 1 ATOM 1371 C CE1 . TYR A 1 168 ? -23.492 64.499 -91.923 1.00 31.47 ? 168 TYR A CE1 1 ATOM 1372 C CE2 . TYR A 1 168 ? -22.536 66.275 -90.607 1.00 29.89 ? 168 TYR A CE2 1 ATOM 1373 C CZ . TYR A 1 168 ? -23.349 65.160 -90.704 1.00 28.23 ? 168 TYR A CZ 1 ATOM 1374 O OH . TYR A 1 168 ? -24.000 64.681 -89.593 1.00 33.04 ? 168 TYR A OH 1 ATOM 1375 N N . ASN A 1 169 ? -24.280 68.470 -93.717 1.00 26.96 ? 169 ASN A N 1 ATOM 1376 C CA . ASN A 1 169 ? -25.078 69.231 -92.744 1.00 33.45 ? 169 ASN A CA 1 ATOM 1377 C C . ASN A 1 169 ? -25.220 68.475 -91.436 1.00 35.04 ? 169 ASN A C 1 ATOM 1378 O O . ASN A 1 169 ? -25.707 67.325 -91.414 1.00 29.19 ? 169 ASN A O 1 ATOM 1379 C CB . ASN A 1 169 ? -26.472 69.482 -93.351 1.00 31.06 ? 169 ASN A CB 1 ATOM 1380 C CG . ASN A 1 169 ? -27.313 70.404 -92.533 1.00 33.52 ? 169 ASN A CG 1 ATOM 1381 O OD1 . ASN A 1 169 ? -27.538 70.169 -91.336 1.00 35.32 ? 169 ASN A OD1 1 ATOM 1382 N ND2 . ASN A 1 169 ? -27.799 71.488 -93.181 1.00 38.32 ? 169 ASN A ND2 1 ATOM 1383 N N . ASN A 1 170 ? -24.783 69.080 -90.317 1.00 26.06 ? 170 ASN A N 1 ATOM 1384 C CA . ASN A 1 170 ? -25.018 68.420 -89.027 1.00 30.00 ? 170 ASN A CA 1 ATOM 1385 C C . ASN A 1 170 ? -26.479 68.449 -88.568 1.00 31.59 ? 170 ASN A C 1 ATOM 1386 O O . ASN A 1 170 ? -26.935 69.378 -87.886 1.00 30.54 ? 170 ASN A O 1 ATOM 1387 C CB . ASN A 1 170 ? -24.065 68.988 -87.959 1.00 25.13 ? 170 ASN A CB 1 ATOM 1388 C CG . ASN A 1 170 ? -24.188 68.297 -86.629 1.00 30.98 ? 170 ASN A CG 1 ATOM 1389 O OD1 . ASN A 1 170 ? -24.888 67.280 -86.460 1.00 28.53 ? 170 ASN A OD1 1 ATOM 1390 N ND2 . ASN A 1 170 ? -23.468 68.851 -85.627 1.00 23.53 ? 170 ASN A ND2 1 ATOM 1391 N N . THR A 1 171 ? -27.218 67.411 -88.940 1.00 27.93 ? 171 THR A N 1 ATOM 1392 C CA . THR A 1 171 ? -28.620 67.269 -88.570 1.00 29.87 ? 171 THR A CA 1 ATOM 1393 C C . THR A 1 171 ? -28.816 66.672 -87.196 1.00 37.71 ? 171 THR A C 1 ATOM 1394 O O . THR A 1 171 ? -29.941 66.339 -86.818 1.00 36.61 ? 171 THR A O 1 ATOM 1395 C CB . THR A 1 171 ? -29.329 66.370 -89.637 1.00 33.53 ? 171 THR A CB 1 ATOM 1396 O OG1 . THR A 1 171 ? -28.713 65.087 -89.638 1.00 41.08 ? 171 THR A OG1 1 ATOM 1397 C CG2 . THR A 1 171 ? -29.154 66.951 -90.967 1.00 38.88 ? 171 THR A CG2 1 ATOM 1398 N N . ASN A 1 172 ? -27.740 66.495 -86.425 1.00 30.45 ? 172 ASN A N 1 ATOM 1399 C CA . ASN A 1 172 ? -27.891 66.047 -85.046 1.00 29.85 ? 172 ASN A CA 1 ATOM 1400 C C . ASN A 1 172 ? -28.024 67.220 -84.053 1.00 29.47 ? 172 ASN A C 1 ATOM 1401 O O . ASN A 1 172 ? -27.776 68.363 -84.409 1.00 32.74 ? 172 ASN A O 1 ATOM 1402 C CB . ASN A 1 172 ? -26.659 65.240 -84.673 1.00 31.46 ? 172 ASN A CB 1 ATOM 1403 C CG . ASN A 1 172 ? -26.364 64.167 -85.674 1.00 37.39 ? 172 ASN A CG 1 ATOM 1404 O OD1 . ASN A 1 172 ? -26.988 63.130 -85.630 1.00 36.28 ? 172 ASN A OD1 1 ATOM 1405 N ND2 . ASN A 1 172 ? -25.426 64.420 -86.603 1.00 34.98 ? 172 ASN A ND2 1 ATOM 1406 N N . GLN A 1 173 ? -28.340 66.910 -82.802 1.00 31.41 ? 173 GLN A N 1 ATOM 1407 C CA . GLN A 1 173 ? -28.466 67.915 -81.745 1.00 37.59 ? 173 GLN A CA 1 ATOM 1408 C C . GLN A 1 173 ? -27.133 68.135 -81.070 1.00 33.86 ? 173 GLN A C 1 ATOM 1409 O O . GLN A 1 173 ? -27.004 69.039 -80.239 1.00 33.98 ? 173 GLN A O 1 ATOM 1410 C CB . GLN A 1 173 ? -29.414 67.414 -80.662 1.00 41.33 ? 173 GLN A CB 1 ATOM 1411 C CG . GLN A 1 173 ? -30.873 67.251 -81.105 1.00 56.08 ? 173 GLN A CG 1 ATOM 1412 C CD . GLN A 1 173 ? -31.707 68.448 -80.755 1.00 62.96 ? 173 GLN A CD 1 ATOM 1413 O OE1 . GLN A 1 173 ? -32.462 68.426 -79.777 1.00 87.76 ? 173 GLN A OE1 1 ATOM 1414 N NE2 . GLN A 1 173 ? -31.572 69.519 -81.540 1.00 73.21 ? 173 GLN A NE2 1 ATOM 1415 N N . GLU A 1 174 ? -26.167 67.287 -81.386 1.00 28.17 ? 174 GLU A N 1 ATOM 1416 C CA . GLU A 1 174 ? -24.870 67.310 -80.703 1.00 26.01 ? 174 GLU A CA 1 ATOM 1417 C C . GLU A 1 174 ? -23.804 67.929 -81.579 1.00 27.37 ? 174 GLU A C 1 ATOM 1418 O O . GLU A 1 174 ? -23.900 67.877 -82.782 1.00 27.27 ? 174 GLU A O 1 ATOM 1419 C CB . GLU A 1 174 ? -24.454 65.888 -80.328 1.00 27.81 ? 174 GLU A CB 1 ATOM 1420 C CG . GLU A 1 174 ? -25.414 65.202 -79.346 1.00 31.26 ? 174 GLU A CG 1 ATOM 1421 C CD . GLU A 1 174 ? -26.535 64.448 -80.048 1.00 39.52 ? 174 GLU A CD 1 ATOM 1422 O OE1 . GLU A 1 174 ? -27.372 63.871 -79.333 1.00 50.45 ? 174 GLU A OE1 1 ATOM 1423 O OE2 . GLU A 1 174 ? -26.584 64.428 -81.298 1.00 34.33 ? 174 GLU A OE2 1 ATOM 1424 N N . ASP A 1 175 ? -22.814 68.600 -80.984 1.00 23.40 ? 175 ASP A N 1 ATOM 1425 C CA . ASP A 1 175 ? -21.689 69.056 -81.750 1.00 21.59 ? 175 ASP A CA 1 ATOM 1426 C C . ASP A 1 175 ? -20.956 67.852 -82.409 1.00 26.52 ? 175 ASP A C 1 ATOM 1427 O O . ASP A 1 175 ? -20.921 66.768 -81.851 1.00 24.60 ? 175 ASP A O 1 ATOM 1428 C CB . ASP A 1 175 ? -20.644 69.696 -80.848 1.00 23.19 ? 175 ASP A CB 1 ATOM 1429 C CG . ASP A 1 175 ? -21.056 71.054 -80.291 1.00 34.73 ? 175 ASP A CG 1 ATOM 1430 O OD1 . ASP A 1 175 ? -21.860 71.741 -80.934 1.00 29.69 ? 175 ASP A OD1 1 ATOM 1431 O OD2 . ASP A 1 175 ? -20.508 71.426 -79.223 1.00 33.48 ? 175 ASP A OD2 1 ATOM 1432 N N . LEU A 1 176 ? -20.293 68.107 -83.524 1.00 22.40 ? 176 LEU A N 1 ATOM 1433 C CA . LEU A 1 176 ? -19.559 67.043 -84.236 1.00 23.54 ? 176 LEU A CA 1 ATOM 1434 C C . LEU A 1 176 ? -18.112 67.442 -84.427 1.00 22.58 ? 176 LEU A C 1 ATOM 1435 O O . LEU A 1 176 ? -17.844 68.532 -85.001 1.00 24.97 ? 176 LEU A O 1 ATOM 1436 C CB . LEU A 1 176 ? -20.201 66.903 -85.619 1.00 22.50 ? 176 LEU A CB 1 ATOM 1437 C CG . LEU A 1 176 ? -19.707 65.784 -86.506 1.00 32.39 ? 176 LEU A CG 1 ATOM 1438 C CD1 . LEU A 1 176 ? -20.032 64.408 -85.858 1.00 26.37 ? 176 LEU A CD1 1 ATOM 1439 C CD2 . LEU A 1 176 ? -20.407 65.914 -87.845 1.00 27.97 ? 176 LEU A CD2 1 ATOM 1440 N N . LEU A 1 177 ? -17.178 66.577 -84.032 1.00 19.42 ? 177 LEU A N 1 ATOM 1441 C CA . LEU A 1 177 ? -15.775 66.788 -84.286 1.00 20.24 ? 177 LEU A CA 1 ATOM 1442 C C . LEU A 1 177 ? -15.472 66.188 -85.694 1.00 22.89 ? 177 LEU A C 1 ATOM 1443 O O . LEU A 1 177 ? -15.624 64.974 -85.878 1.00 23.86 ? 177 LEU A O 1 ATOM 1444 C CB . LEU A 1 177 ? -14.946 66.042 -83.223 1.00 19.22 ? 177 LEU A CB 1 ATOM 1445 C CG . LEU A 1 177 ? -13.452 65.992 -83.545 1.00 18.74 ? 177 LEU A CG 1 ATOM 1446 C CD1 . LEU A 1 177 ? -12.826 67.406 -83.643 1.00 21.10 ? 177 LEU A CD1 1 ATOM 1447 C CD2 . LEU A 1 177 ? -12.730 65.138 -82.456 1.00 19.72 ? 177 LEU A CD2 1 ATOM 1448 N N . VAL A 1 178 ? -15.069 67.034 -86.632 1.00 19.88 ? 178 VAL A N 1 ATOM 1449 C CA . VAL A 1 178 ? -14.738 66.646 -88.039 1.00 19.80 ? 178 VAL A CA 1 ATOM 1450 C C . VAL A 1 178 ? -13.245 66.813 -88.292 1.00 26.43 ? 178 VAL A C 1 ATOM 1451 O O . VAL A 1 178 ? -12.650 67.837 -87.937 1.00 23.48 ? 178 VAL A O 1 ATOM 1452 C CB . VAL A 1 178 ? -15.565 67.483 -89.041 1.00 19.69 ? 178 VAL A CB 1 ATOM 1453 C CG1 . VAL A 1 178 ? -15.244 67.094 -90.486 1.00 23.14 ? 178 VAL A CG1 1 ATOM 1454 C CG2 . VAL A 1 178 ? -17.076 67.380 -88.693 1.00 23.19 ? 178 VAL A CG2 1 ATOM 1455 N N . LEU A 1 179 ? -12.637 65.787 -88.891 1.00 21.89 ? 179 LEU A N 1 ATOM 1456 C CA . LEU A 1 179 ? -11.219 65.723 -89.183 1.00 20.49 ? 179 LEU A CA 1 ATOM 1457 C C . LEU A 1 179 ? -11.008 65.541 -90.695 1.00 25.77 ? 179 LEU A C 1 ATOM 1458 O O . LEU A 1 179 ? -11.785 64.840 -91.354 1.00 23.30 ? 179 LEU A O 1 ATOM 1459 C CB . LEU A 1 179 ? -10.657 64.491 -88.466 1.00 22.45 ? 179 LEU A CB 1 ATOM 1460 C CG . LEU A 1 179 ? -11.063 64.367 -87.001 1.00 30.52 ? 179 LEU A CG 1 ATOM 1461 C CD1 . LEU A 1 179 ? -10.814 62.984 -86.417 1.00 36.85 ? 179 LEU A CD1 1 ATOM 1462 C CD2 . LEU A 1 179 ? -10.224 65.337 -86.262 1.00 30.58 ? 179 LEU A CD2 1 ATOM 1463 N N . TRP A 1 180 ? -9.991 66.204 -91.234 1.00 22.31 ? 180 TRP A N 1 ATOM 1464 C CA . TRP A 1 180 ? -9.610 66.069 -92.646 1.00 22.23 ? 180 TRP A CA 1 ATOM 1465 C C . TRP A 1 180 ? -8.139 66.402 -92.749 1.00 26.48 ? 180 TRP A C 1 ATOM 1466 O O . TRP A 1 180 ? -7.497 66.764 -91.736 1.00 26.01 ? 180 TRP A O 1 ATOM 1467 C CB . TRP A 1 180 ? -10.449 66.978 -93.580 1.00 21.81 ? 180 TRP A CB 1 ATOM 1468 C CG . TRP A 1 180 ? -10.209 68.466 -93.335 1.00 23.31 ? 180 TRP A CG 1 ATOM 1469 C CD1 . TRP A 1 180 ? -9.346 69.292 -94.003 1.00 26.49 ? 180 TRP A CD1 1 ATOM 1470 C CD2 . TRP A 1 180 ? -10.845 69.266 -92.337 1.00 21.84 ? 180 TRP A CD2 1 ATOM 1471 N NE1 . TRP A 1 180 ? -9.429 70.583 -93.485 1.00 25.86 ? 180 TRP A NE1 1 ATOM 1472 C CE2 . TRP A 1 180 ? -10.372 70.590 -92.490 1.00 23.91 ? 180 TRP A CE2 1 ATOM 1473 C CE3 . TRP A 1 180 ? -11.795 68.997 -91.332 1.00 22.73 ? 180 TRP A CE3 1 ATOM 1474 C CZ2 . TRP A 1 180 ? -10.789 71.639 -91.642 1.00 28.63 ? 180 TRP A CZ2 1 ATOM 1475 C CZ3 . TRP A 1 180 ? -12.224 70.052 -90.490 1.00 27.76 ? 180 TRP A CZ3 1 ATOM 1476 C CH2 . TRP A 1 180 ? -11.694 71.344 -90.644 1.00 29.22 ? 180 TRP A CH2 1 ATOM 1477 N N . GLY A 1 181 ? -7.556 66.240 -93.946 1.00 23.63 ? 181 GLY A N 1 ATOM 1478 C CA . GLY A 1 181 ? -6.128 66.438 -94.072 1.00 25.06 ? 181 GLY A CA 1 ATOM 1479 C C . GLY A 1 181 ? -5.705 66.870 -95.445 1.00 24.59 ? 181 GLY A C 1 ATOM 1480 O O . GLY A 1 181 ? -6.510 66.885 -96.390 1.00 27.64 ? 181 GLY A O 1 ATOM 1481 N N . ILE A 1 182 ? -4.426 67.222 -95.567 1.00 27.67 ? 182 ILE A N 1 ATOM 1482 C CA . ILE A 1 182 ? -3.838 67.501 -96.877 1.00 24.56 ? 182 ILE A CA 1 ATOM 1483 C C . ILE A 1 182 ? -2.541 66.773 -97.016 1.00 26.33 ? 182 ILE A C 1 ATOM 1484 O O . ILE A 1 182 ? -1.810 66.578 -96.050 1.00 25.86 ? 182 ILE A O 1 ATOM 1485 C CB . ILE A 1 182 ? -3.635 69.037 -97.131 1.00 26.31 ? 182 ILE A CB 1 ATOM 1486 C CG1 . ILE A 1 182 ? -3.112 69.323 -98.538 1.00 27.93 ? 182 ILE A CG1 1 ATOM 1487 C CG2 . ILE A 1 182 ? -2.687 69.652 -96.094 1.00 30.16 ? 182 ILE A CG2 1 ATOM 1488 C CD1 . ILE A 1 182 ? -3.104 70.853 -98.842 1.00 29.68 ? 182 ILE A CD1 1 ATOM 1489 N N . HIS A 1 183 ? -2.233 66.330 -98.241 1.00 26.24 ? 183 HIS A N 1 ATOM 1490 C CA . HIS A 1 183 ? -0.989 65.641 -98.462 1.00 26.34 ? 183 HIS A CA 1 ATOM 1491 C C . HIS A 1 183 ? 0.017 66.628 -99.073 1.00 23.88 ? 183 HIS A C 1 ATOM 1492 O O . HIS A 1 183 ? -0.288 67.291 -100.107 1.00 26.11 ? 183 HIS A O 1 ATOM 1493 C CB . HIS A 1 183 ? -1.194 64.505 -99.498 1.00 28.26 ? 183 HIS A CB 1 ATOM 1494 C CG . HIS A 1 183 ? 0.068 63.777 -99.854 1.00 24.55 ? 183 HIS A CG 1 ATOM 1495 N ND1 . HIS A 1 183 ? 0.336 63.351 -101.147 1.00 30.15 ? 183 HIS A ND1 1 ATOM 1496 C CD2 . HIS A 1 183 ? 1.134 63.385 -99.103 1.00 30.62 ? 183 HIS A CD2 1 ATOM 1497 C CE1 . HIS A 1 183 ? 1.503 62.723 -101.169 1.00 28.08 ? 183 HIS A CE1 1 ATOM 1498 N NE2 . HIS A 1 183 ? 2.015 62.741 -99.947 1.00 32.69 ? 183 HIS A NE2 1 ATOM 1499 N N . HIS A 1 184 ? 1.191 66.690 -98.462 1.00 29.04 ? 184 HIS A N 1 ATOM 1500 C CA . HIS A 1 184 ? 2.324 67.477 -98.989 1.00 28.95 ? 184 HIS A CA 1 ATOM 1501 C C . HIS A 1 184 ? 3.318 66.536 -99.640 1.00 22.61 ? 184 HIS A C 1 ATOM 1502 O O . HIS A 1 184 ? 4.116 65.886 -98.991 1.00 30.62 ? 184 HIS A O 1 ATOM 1503 C CB . HIS A 1 184 ? 3.039 68.181 -97.828 1.00 28.00 ? 184 HIS A CB 1 ATOM 1504 C CG . HIS A 1 184 ? 2.156 69.136 -97.058 1.00 27.38 ? 184 HIS A CG 1 ATOM 1505 N ND1 . HIS A 1 184 ? 1.669 70.291 -97.611 1.00 28.51 ? 184 HIS A ND1 1 ATOM 1506 C CD2 . HIS A 1 184 ? 1.732 69.136 -95.768 1.00 32.17 ? 184 HIS A CD2 1 ATOM 1507 C CE1 . HIS A 1 184 ? 0.946 70.946 -96.725 1.00 30.41 ? 184 HIS A CE1 1 ATOM 1508 N NE2 . HIS A 1 184 ? 0.981 70.276 -95.588 1.00 28.79 ? 184 HIS A NE2 1 ATOM 1509 N N . PRO A 1 185 ? 3.308 66.488 -100.969 1.00 30.80 ? 185 PRO A N 1 ATOM 1510 C CA . PRO A 1 185 ? 4.189 65.520 -101.635 1.00 34.13 ? 185 PRO A CA 1 ATOM 1511 C C . PRO A 1 185 ? 5.668 65.934 -101.720 1.00 40.92 ? 185 PRO A C 1 ATOM 1512 O O . PRO A 1 185 ? 6.070 67.004 -101.230 1.00 32.69 ? 185 PRO A O 1 ATOM 1513 C CB . PRO A 1 185 ? 3.564 65.379 -103.028 1.00 38.14 ? 185 PRO A CB 1 ATOM 1514 C CG . PRO A 1 185 ? 2.763 66.604 -103.233 1.00 36.54 ? 185 PRO A CG 1 ATOM 1515 C CD . PRO A 1 185 ? 2.458 67.254 -101.884 1.00 28.51 ? 185 PRO A CD 1 ATOM 1516 N N . ASN A 1 186 ? 6.467 65.065 -102.335 1.00 34.79 ? 186 ASN A N 1 ATOM 1517 C CA . ASN A 1 186 ? 7.926 65.180 -102.371 1.00 33.55 ? 186 ASN A CA 1 ATOM 1518 C C . ASN A 1 186 ? 8.465 66.055 -103.483 1.00 46.13 ? 186 ASN A C 1 ATOM 1519 O O . ASN A 1 186 ? 9.442 66.783 -103.280 1.00 41.48 ? 186 ASN A O 1 ATOM 1520 C CB . ASN A 1 186 ? 8.516 63.792 -102.514 1.00 42.22 ? 186 ASN A CB 1 ATOM 1521 C CG . ASN A 1 186 ? 8.229 62.969 -101.329 1.00 44.71 ? 186 ASN A CG 1 ATOM 1522 O OD1 . ASN A 1 186 ? 8.367 63.458 -100.218 1.00 49.71 ? 186 ASN A OD1 1 ATOM 1523 N ND2 . ASN A 1 186 ? 7.789 61.735 -101.524 1.00 52.96 ? 186 ASN A ND2 1 ATOM 1524 N N . ASP A 1 187 ? 7.830 65.967 -104.649 1.00 43.09 ? 187 ASP A N 1 ATOM 1525 C CA . ASP A 1 187 ? 8.225 66.733 -105.823 1.00 45.36 ? 187 ASP A CA 1 ATOM 1526 C C . ASP A 1 187 ? 7.079 66.816 -106.804 1.00 44.35 ? 187 ASP A C 1 ATOM 1527 O O . ASP A 1 187 ? 6.033 66.164 -106.624 1.00 38.72 ? 187 ASP A O 1 ATOM 1528 C CB . ASP A 1 187 ? 9.452 66.097 -106.488 1.00 45.67 ? 187 ASP A CB 1 ATOM 1529 C CG . ASP A 1 187 ? 9.253 64.608 -106.781 1.00 49.93 ? 187 ASP A CG 1 ATOM 1530 O OD1 . ASP A 1 187 ? 10.162 63.818 -106.468 1.00 62.52 ? 187 ASP A OD1 1 ATOM 1531 O OD2 . ASP A 1 187 ? 8.185 64.226 -107.308 1.00 54.09 ? 187 ASP A OD2 1 ATOM 1532 N N . ALA A 1 188 ? 7.277 67.602 -107.859 1.00 39.86 ? 188 ALA A N 1 ATOM 1533 C CA . ALA A 1 188 ? 6.262 67.806 -108.885 1.00 39.01 ? 188 ALA A CA 1 ATOM 1534 C C . ALA A 1 188 ? 5.799 66.519 -109.586 1.00 37.71 ? 188 ALA A C 1 ATOM 1535 O O . ALA A 1 188 ? 4.630 66.416 -110.006 1.00 39.99 ? 188 ALA A O 1 ATOM 1536 C CB . ALA A 1 188 ? 6.752 68.819 -109.930 1.00 42.27 ? 188 ALA A CB 1 ATOM 1537 N N . ALA A 1 189 ? 6.717 65.567 -109.738 1.00 40.46 ? 189 ALA A N 1 ATOM 1538 C CA . ALA A 1 189 ? 6.395 64.359 -110.484 1.00 41.10 ? 189 ALA A CA 1 ATOM 1539 C C . ALA A 1 189 ? 5.409 63.529 -109.671 1.00 44.05 ? 189 ALA A C 1 ATOM 1540 O O . ALA A 1 189 ? 4.466 62.957 -110.198 1.00 37.98 ? 189 ALA A O 1 ATOM 1541 C CB . ALA A 1 189 ? 7.642 63.550 -110.746 1.00 48.58 ? 189 ALA A CB 1 ATOM 1542 N N . GLU A 1 190 ? 5.641 63.457 -108.369 1.00 40.49 ? 190 GLU A N 1 ATOM 1543 C CA . GLU A 1 190 ? 4.737 62.706 -107.519 1.00 37.11 ? 190 GLU A CA 1 ATOM 1544 C C . GLU A 1 190 ? 3.362 63.389 -107.508 1.00 31.92 ? 190 GLU A C 1 ATOM 1545 O O . GLU A 1 190 ? 2.309 62.726 -107.516 1.00 38.56 ? 190 GLU A O 1 ATOM 1546 C CB . GLU A 1 190 ? 5.360 62.604 -106.145 1.00 43.99 ? 190 GLU A CB 1 ATOM 1547 C CG . GLU A 1 190 ? 4.701 61.656 -105.209 1.00 45.28 ? 190 GLU A CG 1 ATOM 1548 C CD . GLU A 1 190 ? 5.416 61.700 -103.894 1.00 54.30 ? 190 GLU A CD 1 ATOM 1549 O OE1 . GLU A 1 190 ? 5.071 62.572 -103.075 1.00 50.45 ? 190 GLU A OE1 1 ATOM 1550 O OE2 . GLU A 1 190 ? 6.364 60.904 -103.705 1.00 66.14 ? 190 GLU A OE2 1 ATOM 1551 N N . GLN A 1 191 ? 3.362 64.726 -107.505 1.00 36.20 ? 191 GLN A N 1 ATOM 1552 C CA . GLN A 1 191 ? 2.135 65.495 -107.548 1.00 33.63 ? 191 GLN A CA 1 ATOM 1553 C C . GLN A 1 191 ? 1.261 65.106 -108.728 1.00 37.81 ? 191 GLN A C 1 ATOM 1554 O O . GLN A 1 191 ? 0.060 64.911 -108.601 1.00 38.00 ? 191 GLN A O 1 ATOM 1555 C CB . GLN A 1 191 ? 2.442 66.997 -107.607 1.00 35.12 ? 191 GLN A CB 1 ATOM 1556 C CG . GLN A 1 191 ? 1.217 67.904 -107.763 1.00 28.39 ? 191 GLN A CG 1 ATOM 1557 C CD . GLN A 1 191 ? 0.283 67.878 -106.537 1.00 35.84 ? 191 GLN A CD 1 ATOM 1558 O OE1 . GLN A 1 191 ? 0.727 67.607 -105.404 1.00 32.92 ? 191 GLN A OE1 1 ATOM 1559 N NE2 . GLN A 1 191 ? -0.983 68.178 -106.760 1.00 31.60 ? 191 GLN A NE2 1 ATOM 1560 N N . THR A 1 192 ? 1.882 65.028 -109.900 1.00 40.06 ? 192 THR A N 1 ATOM 1561 C CA . THR A 1 192 ? 1.186 64.607 -111.103 1.00 35.33 ? 192 THR A CA 1 ATOM 1562 C C . THR A 1 192 ? 0.751 63.144 -111.058 1.00 31.20 ? 192 THR A C 1 ATOM 1563 O O . THR A 1 192 ? -0.340 62.811 -111.479 1.00 36.84 ? 192 THR A O 1 ATOM 1564 C CB . THR A 1 192 ? 2.092 64.795 -112.366 1.00 42.79 ? 192 THR A CB 1 ATOM 1565 O OG1 . THR A 1 192 ? 2.665 66.107 -112.373 1.00 47.86 ? 192 THR A OG1 1 ATOM 1566 C CG2 . THR A 1 192 ? 1.252 64.633 -113.596 1.00 51.58 ? 192 THR A CG2 1 ATOM 1567 N N . LYS A 1 193 ? 1.615 62.265 -110.574 1.00 34.94 ? 193 LYS A N 1 ATOM 1568 C CA . LYS A 1 193 ? 1.278 60.862 -110.537 1.00 37.68 ? 193 LYS A CA 1 ATOM 1569 C C . LYS A 1 193 ? 0.043 60.604 -109.685 1.00 45.31 ? 193 LYS A C 1 ATOM 1570 O O . LYS A 1 193 ? -0.788 59.755 -110.016 1.00 36.13 ? 193 LYS A O 1 ATOM 1571 C CB . LYS A 1 193 ? 2.443 60.096 -109.958 1.00 36.95 ? 193 LYS A CB 1 ATOM 1572 C CG . LYS A 1 193 ? 2.115 58.662 -109.711 1.00 50.35 ? 193 LYS A CG 1 ATOM 1573 C CD . LYS A 1 193 ? 3.263 57.945 -109.069 1.00 52.02 ? 193 LYS A CD 1 ATOM 1574 C CE . LYS A 1 193 ? 3.019 56.442 -109.102 1.00 77.46 ? 193 LYS A CE 1 ATOM 1575 N NZ . LYS A 1 193 ? 4.083 55.685 -108.383 1.00 72.02 ? 193 LYS A NZ 1 ATOM 1576 N N . LEU A 1 194 ? -0.088 61.329 -108.572 1.00 38.22 ? 194 LEU A N 1 ATOM 1577 C CA . LEU A 1 194 ? -1.215 61.060 -107.660 1.00 32.74 ? 194 LEU A CA 1 ATOM 1578 C C . LEU A 1 194 ? -2.448 61.830 -107.993 1.00 30.36 ? 194 LEU A C 1 ATOM 1579 O O . LEU A 1 194 ? -3.571 61.302 -107.869 1.00 33.20 ? 194 LEU A O 1 ATOM 1580 C CB . LEU A 1 194 ? -0.811 61.391 -106.211 1.00 32.38 ? 194 LEU A CB 1 ATOM 1581 C CG . LEU A 1 194 ? 0.338 60.555 -105.696 1.00 29.89 ? 194 LEU A CG 1 ATOM 1582 C CD1 . LEU A 1 194 ? 0.728 60.977 -104.272 1.00 36.08 ? 194 LEU A CD1 1 ATOM 1583 C CD2 . LEU A 1 194 ? -0.045 59.097 -105.705 1.00 39.76 ? 194 LEU A CD2 1 ATOM 1584 N N . TYR A 1 195 ? -2.276 63.090 -108.417 1.00 33.19 ? 195 TYR A N 1 ATOM 1585 C CA . TYR A 1 195 ? -3.417 63.991 -108.521 1.00 31.45 ? 195 TYR A CA 1 ATOM 1586 C C . TYR A 1 195 ? -3.648 64.648 -109.885 1.00 33.98 ? 195 TYR A C 1 ATOM 1587 O O . TYR A 1 195 ? -4.630 65.371 -110.054 1.00 32.47 ? 195 TYR A O 1 ATOM 1588 C CB . TYR A 1 195 ? -3.362 65.083 -107.438 1.00 33.16 ? 195 TYR A CB 1 ATOM 1589 C CG . TYR A 1 195 ? -2.991 64.534 -106.101 1.00 30.38 ? 195 TYR A CG 1 ATOM 1590 C CD1 . TYR A 1 195 ? -1.755 64.805 -105.528 1.00 30.89 ? 195 TYR A CD1 1 ATOM 1591 C CD2 . TYR A 1 195 ? -3.887 63.723 -105.395 1.00 29.48 ? 195 TYR A CD2 1 ATOM 1592 C CE1 . TYR A 1 195 ? -1.378 64.276 -104.302 1.00 26.73 ? 195 TYR A CE1 1 ATOM 1593 C CE2 . TYR A 1 195 ? -3.525 63.193 -104.154 1.00 27.30 ? 195 TYR A CE2 1 ATOM 1594 C CZ . TYR A 1 195 ? -2.281 63.470 -103.616 1.00 29.43 ? 195 TYR A CZ 1 ATOM 1595 O OH . TYR A 1 195 ? -1.912 62.924 -102.415 1.00 29.09 ? 195 TYR A OH 1 ATOM 1596 N N . GLN A 1 196 ? -2.729 64.401 -110.827 1.00 37.26 ? 196 GLN A N 1 ATOM 1597 C CA . GLN A 1 196 ? -2.793 64.965 -112.189 1.00 41.77 ? 196 GLN A CA 1 ATOM 1598 C C . GLN A 1 196 ? -2.530 66.466 -112.215 1.00 46.86 ? 196 GLN A C 1 ATOM 1599 O O . GLN A 1 196 ? -1.566 66.944 -112.816 1.00 42.49 ? 196 GLN A O 1 ATOM 1600 C CB . GLN A 1 196 ? -4.155 64.685 -112.845 1.00 44.95 ? 196 GLN A CB 1 ATOM 1601 C CG . GLN A 1 196 ? -4.136 64.845 -114.380 1.00 51.91 ? 196 GLN A CG 1 ATOM 1602 C CD . GLN A 1 196 ? -3.279 63.780 -115.044 1.00 57.28 ? 196 GLN A CD 1 ATOM 1603 O OE1 . GLN A 1 196 ? -3.184 62.632 -114.562 1.00 49.55 ? 196 GLN A OE1 1 ATOM 1604 N NE2 . GLN A 1 196 ? -2.646 64.145 -116.148 1.00 61.17 ? 196 GLN A NE2 1 ATOM 1605 N N . ASN A 1 197 ? -3.404 67.198 -111.545 1.00 40.42 ? 197 ASN A N 1 ATOM 1606 C CA . ASN A 1 197 ? -3.338 68.653 -111.500 1.00 43.00 ? 197 ASN A CA 1 ATOM 1607 C C . ASN A 1 197 ? -2.117 69.164 -110.735 1.00 39.21 ? 197 ASN A C 1 ATOM 1608 O O . ASN A 1 197 ? -1.870 68.754 -109.593 1.00 39.00 ? 197 ASN A O 1 ATOM 1609 C CB . ASN A 1 197 ? -4.603 69.190 -110.850 1.00 39.41 ? 197 ASN A CB 1 ATOM 1610 C CG . ASN A 1 197 ? -5.867 68.608 -111.444 1.00 52.77 ? 197 ASN A CG 1 ATOM 1611 O OD1 . ASN A 1 197 ? -5.993 68.487 -112.660 1.00 43.71 ? 197 ASN A OD1 1 ATOM 1612 N ND2 . ASN A 1 197 ? -6.836 68.265 -110.579 1.00 34.11 ? 197 ASN A ND2 1 ATOM 1613 N N . PRO A 1 198 ? -1.333 70.052 -111.353 1.00 40.67 ? 198 PRO A N 1 ATOM 1614 C CA . PRO A 1 198 ? -0.070 70.478 -110.743 1.00 40.46 ? 198 PRO A CA 1 ATOM 1615 C C . PRO A 1 198 ? -0.237 71.495 -109.607 1.00 34.36 ? 198 PRO A C 1 ATOM 1616 O O . PRO A 1 198 ? 0.647 71.569 -108.721 1.00 41.88 ? 198 PRO A O 1 ATOM 1617 C CB . PRO A 1 198 ? 0.653 71.158 -111.914 1.00 40.55 ? 198 PRO A CB 1 ATOM 1618 C CG . PRO A 1 198 ? -0.481 71.763 -112.684 1.00 39.11 ? 198 PRO A CG 1 ATOM 1619 C CD . PRO A 1 198 ? -1.550 70.692 -112.666 1.00 51.53 ? 198 PRO A CD 1 ATOM 1620 N N . THR A 1 199 ? -1.325 72.242 -109.642 1.00 35.09 ? 199 THR A N 1 ATOM 1621 C CA . THR A 1 199 ? -1.549 73.365 -108.748 1.00 39.62 ? 199 THR A CA 1 ATOM 1622 C C . THR A 1 199 ? -2.894 73.212 -108.058 1.00 38.39 ? 199 THR A C 1 ATOM 1623 O O . THR A 1 199 ? -3.930 73.396 -108.680 1.00 39.88 ? 199 THR A O 1 ATOM 1624 C CB . THR A 1 199 ? -1.581 74.658 -109.539 1.00 45.69 ? 199 THR A CB 1 ATOM 1625 O OG1 . THR A 1 199 ? -0.316 74.821 -110.188 1.00 45.46 ? 199 THR A OG1 1 ATOM 1626 C CG2 . THR A 1 199 ? -1.841 75.830 -108.606 1.00 46.39 ? 199 THR A CG2 1 ATOM 1627 N N . THR A 1 200 ? -2.877 72.895 -106.766 1.00 39.01 ? 200 THR A N 1 ATOM 1628 C CA . THR A 1 200 ? -4.078 72.417 -106.117 1.00 38.72 ? 200 THR A CA 1 ATOM 1629 C C . THR A 1 200 ? -4.370 73.158 -104.813 1.00 43.78 ? 200 THR A C 1 ATOM 1630 O O . THR A 1 200 ? -3.493 73.840 -104.270 1.00 39.63 ? 200 THR A O 1 ATOM 1631 C CB . THR A 1 200 ? -3.981 70.885 -105.825 1.00 36.05 ? 200 THR A CB 1 ATOM 1632 O OG1 . THR A 1 200 ? -2.878 70.636 -104.948 1.00 34.86 ? 200 THR A OG1 1 ATOM 1633 C CG2 . THR A 1 200 ? -3.779 70.084 -107.137 1.00 30.41 ? 200 THR A CG2 1 ATOM 1634 N N . TYR A 1 201 ? -5.598 72.991 -104.322 1.00 34.01 ? 201 TYR A N 1 ATOM 1635 C CA . TYR A 1 201 ? -6.051 73.555 -103.057 1.00 36.99 ? 201 TYR A CA 1 ATOM 1636 C C . TYR A 1 201 ? -7.120 72.680 -102.409 1.00 38.73 ? 201 TYR A C 1 ATOM 1637 O O . TYR A 1 201 ? -7.717 71.830 -103.051 1.00 32.13 ? 201 TYR A O 1 ATOM 1638 C CB . TYR A 1 201 ? -6.685 74.949 -103.306 1.00 35.16 ? 201 TYR A CB 1 ATOM 1639 C CG . TYR A 1 201 ? -7.934 74.870 -104.155 1.00 30.44 ? 201 TYR A CG 1 ATOM 1640 C CD1 . TYR A 1 201 ? -9.181 74.806 -103.577 1.00 29.92 ? 201 TYR A CD1 1 ATOM 1641 C CD2 . TYR A 1 201 ? -7.852 74.739 -105.538 1.00 38.11 ? 201 TYR A CD2 1 ATOM 1642 C CE1 . TYR A 1 201 ? -10.364 74.701 -104.349 1.00 35.73 ? 201 TYR A CE1 1 ATOM 1643 C CE2 . TYR A 1 201 ? -9.005 74.607 -106.321 1.00 36.35 ? 201 TYR A CE2 1 ATOM 1644 C CZ . TYR A 1 201 ? -10.255 74.579 -105.721 1.00 37.06 ? 201 TYR A CZ 1 ATOM 1645 O OH . TYR A 1 201 ? -11.412 74.456 -106.444 1.00 40.91 ? 201 TYR A OH 1 ATOM 1646 N N . ILE A 1 202 ? -7.387 72.921 -101.128 1.00 30.25 ? 202 ILE A N 1 ATOM 1647 C CA . ILE A 1 202 ? -8.573 72.417 -100.466 1.00 30.29 ? 202 ILE A CA 1 ATOM 1648 C C . ILE A 1 202 ? -9.157 73.600 -99.720 1.00 29.87 ? 202 ILE A C 1 ATOM 1649 O O . ILE A 1 202 ? -8.496 74.181 -98.868 1.00 36.30 ? 202 ILE A O 1 ATOM 1650 C CB . ILE A 1 202 ? -8.211 71.384 -99.414 1.00 29.76 ? 202 ILE A CB 1 ATOM 1651 C CG1 . ILE A 1 202 ? -7.503 70.193 -100.034 1.00 30.16 ? 202 ILE A CG1 1 ATOM 1652 C CG2 . ILE A 1 202 ? -9.433 70.940 -98.621 1.00 32.68 ? 202 ILE A CG2 1 ATOM 1653 C CD1 . ILE A 1 202 ? -6.693 69.457 -99.030 1.00 35.60 ? 202 ILE A CD1 1 ATOM 1654 N N . SER A 1 203 ? -10.383 73.944 -100.043 1.00 30.44 ? 203 SER A N 1 ATOM 1655 C CA . SER A 1 203 ? -11.063 75.005 -99.335 1.00 34.14 ? 203 SER A CA 1 ATOM 1656 C C . SER A 1 203 ? -12.068 74.382 -98.401 1.00 33.23 ? 203 SER A C 1 ATOM 1657 O O . SER A 1 203 ? -12.740 73.415 -98.747 1.00 29.71 ? 203 SER A O 1 ATOM 1658 C CB . SER A 1 203 ? -11.725 75.993 -100.321 1.00 31.23 ? 203 SER A CB 1 ATOM 1659 O OG . SER A 1 203 ? -12.958 75.508 -100.790 1.00 41.85 ? 203 SER A OG 1 ATOM 1660 N N . VAL A 1 204 ? -12.157 74.901 -97.180 1.00 24.69 ? 204 VAL A N 1 ATOM 1661 C CA . VAL A 1 204 ? -13.143 74.407 -96.240 1.00 24.76 ? 204 VAL A CA 1 ATOM 1662 C C . VAL A 1 204 ? -13.871 75.571 -95.556 1.00 35.54 ? 204 VAL A C 1 ATOM 1663 O O . VAL A 1 204 ? -13.224 76.507 -95.077 1.00 32.57 ? 204 VAL A O 1 ATOM 1664 C CB . VAL A 1 204 ? -12.469 73.511 -95.106 1.00 27.32 ? 204 VAL A CB 1 ATOM 1665 C CG1 . VAL A 1 204 ? -13.552 72.865 -94.232 1.00 30.44 ? 204 VAL A CG1 1 ATOM 1666 C CG2 . VAL A 1 204 ? -11.570 72.435 -95.713 1.00 25.13 ? 204 VAL A CG2 1 ATOM 1667 N N . GLY A 1 205 ? -15.197 75.512 -95.538 1.00 28.10 ? 205 GLY A N 1 ATOM 1668 C CA . GLY A 1 205 ? -16.028 76.559 -94.927 1.00 29.22 ? 205 GLY A CA 1 ATOM 1669 C C . GLY A 1 205 ? -17.126 76.046 -94.034 1.00 31.84 ? 205 GLY A C 1 ATOM 1670 O O . GLY A 1 205 ? -17.727 74.995 -94.346 1.00 32.21 ? 205 GLY A O 1 ATOM 1671 N N . THR A 1 206 ? -17.417 76.742 -92.919 1.00 25.55 ? 206 THR A N 1 ATOM 1672 C CA . THR A 1 206 ? -18.639 76.479 -92.156 1.00 23.48 ? 206 THR A CA 1 ATOM 1673 C C . THR A 1 206 ? -19.241 77.863 -91.815 1.00 28.84 ? 206 THR A C 1 ATOM 1674 O O . THR A 1 206 ? -18.970 78.824 -92.534 1.00 30.37 ? 206 THR A O 1 ATOM 1675 C CB . THR A 1 206 ? -18.392 75.698 -90.814 1.00 26.45 ? 206 THR A CB 1 ATOM 1676 O OG1 . THR A 1 206 ? -17.565 76.485 -89.920 1.00 28.36 ? 206 THR A OG1 1 ATOM 1677 C CG2 . THR A 1 206 ? -17.632 74.337 -91.087 1.00 24.16 ? 206 THR A CG2 1 ATOM 1678 N N . SER A 1 207 ? -20.037 77.967 -90.756 1.00 25.93 ? 207 SER A N 1 ATOM 1679 C CA . SER A 1 207 ? -20.467 79.308 -90.369 1.00 28.33 ? 207 SER A CA 1 ATOM 1680 C C . SER A 1 207 ? -19.305 80.142 -89.819 1.00 31.39 ? 207 SER A C 1 ATOM 1681 O O . SER A 1 207 ? -19.375 81.392 -89.829 1.00 30.18 ? 207 SER A O 1 ATOM 1682 C CB . SER A 1 207 ? -21.602 79.232 -89.370 1.00 31.96 ? 207 SER A CB 1 ATOM 1683 O OG . SER A 1 207 ? -21.123 78.631 -88.176 1.00 34.85 ? 207 SER A OG 1 ATOM 1684 N N . THR A 1 208 ? -18.246 79.483 -89.346 1.00 27.36 ? 208 THR A N 1 ATOM 1685 C CA . THR A 1 208 ? -17.067 80.193 -88.774 1.00 24.31 ? 208 THR A CA 1 ATOM 1686 C C . THR A 1 208 ? -15.756 79.908 -89.453 1.00 34.01 ? 208 THR A C 1 ATOM 1687 O O . THR A 1 208 ? -14.862 80.721 -89.443 1.00 36.37 ? 208 THR A O 1 ATOM 1688 C CB . THR A 1 208 ? -16.929 79.874 -87.292 1.00 33.23 ? 208 THR A CB 1 ATOM 1689 O OG1 . THR A 1 208 ? -16.964 78.443 -87.132 1.00 32.89 ? 208 THR A OG1 1 ATOM 1690 C CG2 . THR A 1 208 ? -18.075 80.479 -86.542 1.00 32.28 ? 208 THR A CG2 1 ATOM 1691 N N . LEU A 1 209 ? -15.615 78.726 -90.052 1.00 27.79 ? 209 LEU A N 1 ATOM 1692 C CA . LEU A 1 209 ? -14.356 78.406 -90.661 1.00 28.52 ? 209 LEU A CA 1 ATOM 1693 C C . LEU A 1 209 ? -14.264 78.970 -92.060 1.00 28.84 ? 209 LEU A C 1 ATOM 1694 O O . LEU A 1 209 ? -15.251 78.964 -92.786 1.00 32.66 ? 209 LEU A O 1 ATOM 1695 C CB . LEU A 1 209 ? -14.226 76.850 -90.716 1.00 30.11 ? 209 LEU A CB 1 ATOM 1696 C CG . LEU A 1 209 ? -12.894 76.310 -91.185 1.00 35.58 ? 209 LEU A CG 1 ATOM 1697 C CD1 . LEU A 1 209 ? -11.821 76.628 -90.156 1.00 32.35 ? 209 LEU A CD1 1 ATOM 1698 C CD2 . LEU A 1 209 ? -13.065 74.794 -91.319 1.00 33.72 ? 209 LEU A CD2 1 ATOM 1699 N N . ASN A 1 210 ? -13.093 79.462 -92.441 1.00 27.42 ? 210 ASN A N 1 ATOM 1700 C CA . ASN A 1 210 ? -12.838 80.000 -93.781 1.00 31.86 ? 210 ASN A CA 1 ATOM 1701 C C . ASN A 1 210 ? -11.431 79.626 -94.214 1.00 33.37 ? 210 ASN A C 1 ATOM 1702 O O . ASN A 1 210 ? -10.504 80.449 -94.196 1.00 34.09 ? 210 ASN A O 1 ATOM 1703 C CB . ASN A 1 210 ? -13.049 81.547 -93.804 1.00 29.86 ? 210 ASN A CB 1 ATOM 1704 C CG . ASN A 1 210 ? -12.772 82.161 -95.183 1.00 38.65 ? 210 ASN A CG 1 ATOM 1705 O OD1 . ASN A 1 210 ? -12.858 81.480 -96.221 1.00 35.62 ? 210 ASN A OD1 1 ATOM 1706 N ND2 . ASN A 1 210 ? -12.398 83.435 -95.196 1.00 32.28 ? 210 ASN A ND2 1 ATOM 1707 N N . GLN A 1 211 ? -11.231 78.360 -94.588 1.00 27.19 ? 211 GLN A N 1 ATOM 1708 C CA . GLN A 1 211 ? -9.888 77.851 -94.736 1.00 29.91 ? 211 GLN A CA 1 ATOM 1709 C C . GLN A 1 211 ? -9.550 77.602 -96.206 1.00 30.58 ? 211 GLN A C 1 ATOM 1710 O O . GLN A 1 211 ? -10.403 77.164 -96.987 1.00 35.18 ? 211 GLN A O 1 ATOM 1711 C CB . GLN A 1 211 ? -9.824 76.507 -93.966 1.00 29.02 ? 211 GLN A CB 1 ATOM 1712 C CG . GLN A 1 211 ? -8.476 75.896 -93.978 1.00 31.81 ? 211 GLN A CG 1 ATOM 1713 C CD . GLN A 1 211 ? -8.489 74.552 -93.196 1.00 34.38 ? 211 GLN A CD 1 ATOM 1714 O OE1 . GLN A 1 211 ? -8.853 73.506 -93.752 1.00 36.21 ? 211 GLN A OE1 1 ATOM 1715 N NE2 . GLN A 1 211 ? -8.185 74.613 -91.908 1.00 38.86 ? 211 GLN A NE2 1 ATOM 1716 N N A ARG A 1 212 ? -8.317 77.860 -96.600 0.50 33.48 ? 212 ARG A N 1 ATOM 1717 N N B ARG A 1 212 ? -8.330 77.932 -96.586 0.50 33.47 ? 212 ARG A N 1 ATOM 1718 C CA A ARG A 1 212 ? -7.898 77.447 -97.940 0.50 33.84 ? 212 ARG A CA 1 ATOM 1719 C CA B ARG A 1 212 ? -7.814 77.482 -97.870 0.50 33.84 ? 212 ARG A CA 1 ATOM 1720 C C A ARG A 1 212 ? -6.452 76.954 -97.949 0.50 39.06 ? 212 ARG A C 1 ATOM 1721 C C B ARG A 1 212 ? -6.430 76.914 -97.663 0.50 39.06 ? 212 ARG A C 1 ATOM 1722 O O A ARG A 1 212 ? -5.511 77.750 -97.968 0.50 38.59 ? 212 ARG A O 1 ATOM 1723 O O B ARG A 1 212 ? -5.504 77.608 -97.251 0.50 38.60 ? 212 ARG A O 1 ATOM 1724 C CB A ARG A 1 212 ? -8.155 78.547 -98.983 0.50 36.72 ? 212 ARG A CB 1 ATOM 1725 C CB B ARG A 1 212 ? -7.793 78.586 -98.928 0.50 36.73 ? 212 ARG A CB 1 ATOM 1726 C CG A ARG A 1 212 ? -8.052 78.071 -100.441 0.50 34.29 ? 212 ARG A CG 1 ATOM 1727 C CG B ARG A 1 212 ? -7.384 78.064 -100.322 0.50 33.94 ? 212 ARG A CG 1 ATOM 1728 C CD A ARG A 1 212 ? -8.619 79.097 -101.439 0.50 31.89 ? 212 ARG A CD 1 ATOM 1729 C CD B ARG A 1 212 ? -7.423 79.148 -101.389 0.50 34.91 ? 212 ARG A CD 1 ATOM 1730 N NE A ARG A 1 212 ? -8.388 78.713 -102.844 0.50 34.89 ? 212 ARG A NE 1 ATOM 1731 N NE B ARG A 1 212 ? -7.140 78.621 -102.734 0.50 30.51 ? 212 ARG A NE 1 ATOM 1732 C CZ A ARG A 1 212 ? -9.342 78.342 -103.697 0.50 23.63 ? 212 ARG A CZ 1 ATOM 1733 C CZ B ARG A 1 212 ? -5.916 78.508 -103.253 0.50 30.51 ? 212 ARG A CZ 1 ATOM 1734 N NH1 A ARG A 1 212 ? -10.599 78.311 -103.310 0.50 21.18 ? 212 ARG A NH1 1 ATOM 1735 N NH1 B ARG A 1 212 ? -4.864 78.843 -102.537 0.50 34.77 ? 212 ARG A NH1 1 ATOM 1736 N NH2 A ARG A 1 212 ? -9.026 78.027 -104.949 0.50 38.24 ? 212 ARG A NH2 1 ATOM 1737 N NH2 B ARG A 1 212 ? -5.752 78.040 -104.476 0.50 36.12 ? 212 ARG A NH2 1 ATOM 1738 N N . LEU A 1 213 ? -6.302 75.628 -97.929 1.00 34.70 ? 213 LEU A N 1 ATOM 1739 C CA . LEU A 1 213 ? -5.009 74.957 -97.780 1.00 33.49 ? 213 LEU A CA 1 ATOM 1740 C C . LEU A 1 213 ? -4.350 74.739 -99.117 1.00 40.71 ? 213 LEU A C 1 ATOM 1741 O O . LEU A 1 213 ? -5.032 74.510 -100.104 1.00 33.98 ? 213 LEU A O 1 ATOM 1742 C CB . LEU A 1 213 ? -5.210 73.593 -97.101 1.00 38.06 ? 213 LEU A CB 1 ATOM 1743 C CG . LEU A 1 213 ? -5.971 73.555 -95.798 1.00 36.39 ? 213 LEU A CG 1 ATOM 1744 C CD1 . LEU A 1 213 ? -6.214 72.089 -95.314 1.00 34.90 ? 213 LEU A CD1 1 ATOM 1745 C CD2 . LEU A 1 213 ? -5.259 74.355 -94.722 1.00 33.44 ? 213 LEU A CD2 1 ATOM 1746 N N . VAL A 1 214 ? -3.021 74.806 -99.151 1.00 42.45 ? 214 VAL A N 1 ATOM 1747 C CA . VAL A 1 214 ? -2.265 74.552 -100.371 1.00 35.25 ? 214 VAL A CA 1 ATOM 1748 C C . VAL A 1 214 ? -1.106 73.636 -100.058 1.00 34.66 ? 214 VAL A C 1 ATOM 1749 O O . VAL A 1 214 ? -0.427 73.815 -99.047 1.00 38.29 ? 214 VAL A O 1 ATOM 1750 C CB . VAL A 1 214 ? -1.727 75.872 -100.941 1.00 48.13 ? 214 VAL A CB 1 ATOM 1751 C CG1 . VAL A 1 214 ? -0.732 75.625 -102.048 1.00 43.77 ? 214 VAL A CG1 1 ATOM 1752 C CG2 . VAL A 1 214 ? -2.870 76.702 -101.444 1.00 45.49 ? 214 VAL A CG2 1 ATOM 1753 N N . PRO A 1 215 ? -0.855 72.644 -100.927 1.00 38.68 ? 215 PRO A N 1 ATOM 1754 C CA . PRO A 1 215 ? 0.187 71.690 -100.573 1.00 35.09 ? 215 PRO A CA 1 ATOM 1755 C C . PRO A 1 215 ? 1.514 72.371 -100.655 1.00 36.76 ? 215 PRO A C 1 ATOM 1756 O O . PRO A 1 215 ? 1.717 73.230 -101.529 1.00 41.89 ? 215 PRO A O 1 ATOM 1757 C CB . PRO A 1 215 ? 0.098 70.627 -101.689 1.00 38.52 ? 215 PRO A CB 1 ATOM 1758 C CG . PRO A 1 215 ? -1.297 70.766 -102.206 1.00 40.16 ? 215 PRO A CG 1 ATOM 1759 C CD . PRO A 1 215 ? -1.571 72.251 -102.151 1.00 40.57 ? 215 PRO A CD 1 ATOM 1760 N N . ARG A 1 216 ? 2.413 71.974 -99.773 1.00 30.67 ? 216 ARG A N 1 ATOM 1761 C CA . ARG A 1 216 ? 3.769 72.491 -99.839 1.00 37.54 ? 216 ARG A CA 1 ATOM 1762 C C . ARG A 1 216 ? 4.716 71.443 -100.276 1.00 37.39 ? 216 ARG A C 1 ATOM 1763 O O . ARG A 1 216 ? 4.916 70.443 -99.580 1.00 41.04 ? 216 ARG A O 1 ATOM 1764 C CB . ARG A 1 216 ? 4.218 72.992 -98.472 1.00 39.08 ? 216 ARG A CB 1 ATOM 1765 C CG . ARG A 1 216 ? 3.526 74.230 -98.094 1.00 35.35 ? 216 ARG A CG 1 ATOM 1766 C CD . ARG A 1 216 ? 4.146 74.858 -96.821 1.00 41.16 ? 216 ARG A CD 1 ATOM 1767 N NE . ARG A 1 216 ? 3.996 74.017 -95.645 1.00 37.00 ? 216 ARG A NE 1 ATOM 1768 C CZ . ARG A 1 216 ? 2.854 73.849 -94.987 1.00 42.13 ? 216 ARG A CZ 1 ATOM 1769 N NH1 . ARG A 1 216 ? 1.752 74.445 -95.409 1.00 39.64 ? 216 ARG A NH1 1 ATOM 1770 N NH2 . ARG A 1 216 ? 2.811 73.056 -93.920 1.00 38.64 ? 216 ARG A NH2 1 ATOM 1771 N N . ILE A 1 217 ? 5.366 71.679 -101.404 1.00 37.08 ? 217 ILE A N 1 ATOM 1772 C CA . ILE A 1 217 ? 6.477 70.831 -101.697 1.00 39.81 ? 217 ILE A CA 1 ATOM 1773 C C . ILE A 1 217 ? 7.742 71.347 -100.961 1.00 48.68 ? 217 ILE A C 1 ATOM 1774 O O . ILE A 1 217 ? 8.022 72.570 -100.915 1.00 38.43 ? 217 ILE A O 1 ATOM 1775 C CB . ILE A 1 217 ? 6.674 70.652 -103.176 1.00 53.40 ? 217 ILE A CB 1 ATOM 1776 C CG1 . ILE A 1 217 ? 5.703 69.579 -103.683 1.00 49.62 ? 217 ILE A CG1 1 ATOM 1777 C CG2 . ILE A 1 217 ? 8.078 70.227 -103.411 1.00 56.91 ? 217 ILE A CG2 1 ATOM 1778 C CD1 . ILE A 1 217 ? 4.883 69.982 -104.845 1.00 48.07 ? 217 ILE A CD1 1 ATOM 1779 N N . ALA A 1 218 ? 8.417 70.390 -100.313 1.00 44.58 ? 218 ALA A N 1 ATOM 1780 C CA . ALA A 1 218 ? 9.756 70.523 -99.724 1.00 32.31 ? 218 ALA A CA 1 ATOM 1781 C C . ALA A 1 218 ? 10.452 69.159 -99.829 1.00 43.40 ? 218 ALA A C 1 ATOM 1782 O O . ALA A 1 218 ? 9.812 68.087 -100.032 1.00 42.48 ? 218 ALA A O 1 ATOM 1783 C CB . ALA A 1 218 ? 9.698 71.002 -98.201 1.00 46.52 ? 218 ALA A CB 1 ATOM 1784 N N . THR A 1 219 ? 11.775 69.192 -99.705 1.00 40.78 ? 219 THR A N 1 ATOM 1785 C CA . THR A 1 219 ? 12.566 67.972 -99.761 1.00 42.19 ? 219 THR A CA 1 ATOM 1786 C C . THR A 1 219 ? 12.845 67.636 -98.356 1.00 38.94 ? 219 THR A C 1 ATOM 1787 O O . THR A 1 219 ? 13.462 68.425 -97.625 1.00 37.65 ? 219 THR A O 1 ATOM 1788 C CB . THR A 1 219 ? 13.856 68.202 -100.550 1.00 45.62 ? 219 THR A CB 1 ATOM 1789 O OG1 . THR A 1 219 ? 13.483 68.639 -101.856 1.00 46.50 ? 219 THR A OG1 1 ATOM 1790 C CG2 . THR A 1 219 ? 14.689 66.939 -100.635 1.00 44.03 ? 219 THR A CG2 1 ATOM 1791 N N . ARG A 1 220 ? 12.349 66.480 -97.928 1.00 38.59 ? 220 ARG A N 1 ATOM 1792 C CA . ARG A 1 220 ? 12.345 66.176 -96.513 1.00 32.70 ? 220 ARG A CA 1 ATOM 1793 C C . ARG A 1 220 ? 12.990 64.871 -96.241 1.00 39.19 ? 220 ARG A C 1 ATOM 1794 O O . ARG A 1 220 ? 13.078 64.011 -97.123 1.00 35.71 ? 220 ARG A O 1 ATOM 1795 C CB . ARG A 1 220 ? 10.890 66.178 -95.953 1.00 34.30 ? 220 ARG A CB 1 ATOM 1796 C CG . ARG A 1 220 ? 10.040 67.307 -96.501 1.00 38.40 ? 220 ARG A CG 1 ATOM 1797 C CD . ARG A 1 220 ? 8.592 67.251 -96.030 1.00 33.63 ? 220 ARG A CD 1 ATOM 1798 N NE . ARG A 1 220 ? 7.804 68.195 -96.796 1.00 36.39 ? 220 ARG A NE 1 ATOM 1799 C CZ . ARG A 1 220 ? 7.134 67.875 -97.908 1.00 28.51 ? 220 ARG A CZ 1 ATOM 1800 N NH1 . ARG A 1 220 ? 7.149 66.632 -98.345 1.00 32.23 ? 220 ARG A NH1 1 ATOM 1801 N NH2 . ARG A 1 220 ? 6.456 68.793 -98.549 1.00 40.00 ? 220 ARG A NH2 1 ATOM 1802 N N . SER A 1 221 ? 13.453 64.732 -95.013 1.00 30.42 ? 221 SER A N 1 ATOM 1803 C CA . SER A 1 221 ? 13.985 63.492 -94.503 1.00 31.65 ? 221 SER A CA 1 ATOM 1804 C C . SER A 1 221 ? 12.897 62.405 -94.514 1.00 38.92 ? 221 SER A C 1 ATOM 1805 O O . SER A 1 221 ? 11.721 62.667 -94.261 1.00 30.14 ? 221 SER A O 1 ATOM 1806 C CB . SER A 1 221 ? 14.512 63.719 -93.088 1.00 38.41 ? 221 SER A CB 1 ATOM 1807 O OG . SER A 1 221 ? 15.269 64.923 -93.077 1.00 33.75 ? 221 SER A OG 1 ATOM 1808 N N . LYS A 1 222 ? 13.276 61.176 -94.826 1.00 35.09 ? 222 LYS A N 1 ATOM 1809 C CA . LYS A 1 222 ? 12.337 60.087 -94.673 1.00 37.51 ? 222 LYS A CA 1 ATOM 1810 C C . LYS A 1 222 ? 12.028 59.804 -93.214 1.00 37.28 ? 222 LYS A C 1 ATOM 1811 O O . LYS A 1 222 ? 12.926 59.716 -92.384 1.00 33.36 ? 222 LYS A O 1 ATOM 1812 C CB . LYS A 1 222 ? 12.846 58.831 -95.404 1.00 39.94 ? 222 LYS A CB 1 ATOM 1813 C CG . LYS A 1 222 ? 12.593 58.925 -96.883 1.00 47.39 ? 222 LYS A CG 1 ATOM 1814 C CD . LYS A 1 222 ? 13.160 57.764 -97.681 1.00 58.20 ? 222 LYS A CD 1 ATOM 1815 C CE . LYS A 1 222 ? 13.079 58.094 -99.179 1.00 47.88 ? 222 LYS A CE 1 ATOM 1816 N NZ . LYS A 1 222 ? 13.504 56.911 -99.989 1.00 78.53 ? 222 LYS A NZ 1 ATOM 1817 N N . VAL A 1 223 ? 10.730 59.688 -92.898 1.00 33.86 ? 223 VAL A N 1 ATOM 1818 C CA . VAL A 1 223 ? 10.289 59.235 -91.605 1.00 32.44 ? 223 VAL A CA 1 ATOM 1819 C C . VAL A 1 223 ? 9.253 58.137 -91.864 1.00 29.89 ? 223 VAL A C 1 ATOM 1820 O O . VAL A 1 223 ? 8.365 58.336 -92.685 1.00 31.47 ? 223 VAL A O 1 ATOM 1821 C CB . VAL A 1 223 ? 9.618 60.407 -90.819 1.00 34.26 ? 223 VAL A CB 1 ATOM 1822 C CG1 . VAL A 1 223 ? 9.005 59.931 -89.481 1.00 30.38 ? 223 VAL A CG1 1 ATOM 1823 C CG2 . VAL A 1 223 ? 10.661 61.494 -90.598 1.00 30.76 ? 223 VAL A CG2 1 ATOM 1824 N N . ASN A 1 224 ? 9.399 57.009 -91.177 1.00 34.53 ? 224 ASN A N 1 ATOM 1825 C CA . ASN A 1 224 ? 8.617 55.801 -91.507 1.00 37.07 ? 224 ASN A CA 1 ATOM 1826 C C . ASN A 1 224 ? 8.660 55.505 -93.010 1.00 39.09 ? 224 ASN A C 1 ATOM 1827 O O . ASN A 1 224 ? 7.657 55.090 -93.597 1.00 39.19 ? 224 ASN A O 1 ATOM 1828 C CB . ASN A 1 224 ? 7.168 55.956 -91.009 1.00 39.34 ? 224 ASN A CB 1 ATOM 1829 C CG . ASN A 1 224 ? 7.076 56.074 -89.496 1.00 39.71 ? 224 ASN A CG 1 ATOM 1830 O OD1 . ASN A 1 224 ? 7.957 55.614 -88.802 1.00 40.55 ? 224 ASN A OD1 1 ATOM 1831 N ND2 . ASN A 1 224 ? 5.974 56.673 -88.967 1.00 38.32 ? 224 ASN A ND2 1 ATOM 1832 N N . GLY A 1 225 ? 9.811 55.738 -93.647 1.00 36.63 ? 225 GLY A N 1 ATOM 1833 C CA . GLY A 1 225 ? 9.952 55.470 -95.068 1.00 38.23 ? 225 GLY A CA 1 ATOM 1834 C C . GLY A 1 225 ? 9.512 56.554 -96.016 1.00 42.27 ? 225 GLY A C 1 ATOM 1835 O O . GLY A 1 225 ? 9.755 56.480 -97.219 1.00 37.65 ? 225 GLY A O 1 ATOM 1836 N N . GLN A 1 226 ? 8.870 57.595 -95.502 1.00 32.93 ? 226 GLN A N 1 ATOM 1837 C CA . GLN A 1 226 ? 8.261 58.542 -96.397 1.00 32.24 ? 226 GLN A CA 1 ATOM 1838 C C . GLN A 1 226 ? 8.844 59.928 -96.209 1.00 36.77 ? 226 GLN A C 1 ATOM 1839 O O . GLN A 1 226 ? 9.063 60.362 -95.065 1.00 35.93 ? 226 GLN A O 1 ATOM 1840 C CB . GLN A 1 226 ? 6.744 58.608 -96.138 1.00 32.63 ? 226 GLN A CB 1 ATOM 1841 C CG . GLN A 1 226 ? 6.069 57.257 -96.139 1.00 38.21 ? 226 GLN A CG 1 ATOM 1842 C CD . GLN A 1 226 ? 6.157 56.609 -97.501 1.00 36.15 ? 226 GLN A CD 1 ATOM 1843 O OE1 . GLN A 1 226 ? 6.107 57.288 -98.514 1.00 39.76 ? 226 GLN A OE1 1 ATOM 1844 N NE2 . GLN A 1 226 ? 6.286 55.284 -97.528 1.00 49.59 ? 226 GLN A NE2 1 ATOM 1845 N N . SER A 1 227 ? 9.053 60.617 -97.320 1.00 35.59 ? 227 SER A N 1 ATOM 1846 C CA . SER A 1 227 ? 9.405 62.019 -97.317 1.00 38.29 ? 227 SER A CA 1 ATOM 1847 C C . SER A 1 227 ? 8.195 62.910 -97.518 1.00 40.37 ? 227 SER A C 1 ATOM 1848 O O . SER A 1 227 ? 8.306 64.139 -97.387 1.00 34.20 ? 227 SER A O 1 ATOM 1849 C CB . SER A 1 227 ? 10.479 62.318 -98.362 1.00 20.00 ? 227 SER A CB 1 ATOM 1850 O OG . SER A 1 227 ? 11.727 61.718 -97.980 1.00 20.00 ? 227 SER A OG 1 ATOM 1851 N N . GLY A 1 228 ? 7.030 62.324 -97.834 1.00 33.32 ? 228 GLY A N 1 ATOM 1852 C CA . GLY A 1 228 ? 5.859 63.156 -98.017 1.00 29.41 ? 228 GLY A CA 1 ATOM 1853 C C . GLY A 1 228 ? 5.345 63.432 -96.598 1.00 29.02 ? 228 GLY A C 1 ATOM 1854 O O . GLY A 1 228 ? 5.797 62.791 -95.657 1.00 29.10 ? 228 GLY A O 1 ATOM 1855 N N . ARG A 1 229 ? 4.393 64.336 -96.459 1.00 27.38 ? 229 ARG A N 1 ATOM 1856 C CA . ARG A 1 229 ? 3.796 64.551 -95.143 1.00 30.95 ? 229 ARG A CA 1 ATOM 1857 C C . ARG A 1 229 ? 2.295 64.664 -95.254 1.00 24.23 ? 229 ARG A C 1 ATOM 1858 O O . ARG A 1 229 ? 1.787 65.205 -96.235 1.00 26.74 ? 229 ARG A O 1 ATOM 1859 C CB . ARG A 1 229 ? 4.331 65.878 -94.578 1.00 27.75 ? 229 ARG A CB 1 ATOM 1860 C CG . ARG A 1 229 ? 5.825 65.859 -94.277 1.00 27.52 ? 229 ARG A CG 1 ATOM 1861 C CD . ARG A 1 229 ? 6.216 64.930 -93.109 1.00 26.53 ? 229 ARG A CD 1 ATOM 1862 N NE . ARG A 1 229 ? 7.655 65.063 -92.872 1.00 29.08 ? 229 ARG A NE 1 ATOM 1863 C CZ . ARG A 1 229 ? 8.582 64.201 -93.289 1.00 39.87 ? 229 ARG A CZ 1 ATOM 1864 N NH1 . ARG A 1 229 ? 8.235 63.109 -93.986 1.00 31.70 ? 229 ARG A NH1 1 ATOM 1865 N NH2 . ARG A 1 229 ? 9.861 64.436 -93.033 1.00 34.27 ? 229 ARG A NH2 1 ATOM 1866 N N . MET A 1 230 ? 1.568 64.210 -94.222 1.00 25.39 ? 230 MET A N 1 ATOM 1867 C CA . MET A 1 230 ? 0.130 64.490 -94.150 1.00 24.52 ? 230 MET A CA 1 ATOM 1868 C C . MET A 1 230 ? -0.138 65.466 -92.979 1.00 28.08 ? 230 MET A C 1 ATOM 1869 O O . MET A 1 230 ? 0.310 65.224 -91.885 1.00 31.32 ? 230 MET A O 1 ATOM 1870 C CB . MET A 1 230 ? -0.630 63.211 -93.811 1.00 25.74 ? 230 MET A CB 1 ATOM 1871 C CG . MET A 1 230 ? -0.558 62.063 -94.923 1.00 31.71 ? 230 MET A CG 1 ATOM 1872 S SD . MET A 1 230 ? -1.562 62.481 -96.301 1.00 32.00 ? 230 MET A SD 1 ATOM 1873 C CE . MET A 1 230 ? -1.031 61.185 -97.498 1.00 32.09 ? 230 MET A CE 1 ATOM 1874 N N . GLU A 1 231 ? -0.845 66.539 -93.248 1.00 28.10 ? 231 GLU A N 1 ATOM 1875 C CA . GLU A 1 231 ? -1.178 67.536 -92.217 1.00 28.34 ? 231 GLU A CA 1 ATOM 1876 C C . GLU A 1 231 ? -2.694 67.516 -91.980 1.00 23.81 ? 231 GLU A C 1 ATOM 1877 O O . GLU A 1 231 ? -3.485 67.775 -92.923 1.00 26.99 ? 231 GLU A O 1 ATOM 1878 C CB . GLU A 1 231 ? -0.765 68.914 -92.736 1.00 26.71 ? 231 GLU A CB 1 ATOM 1879 C CG . GLU A 1 231 ? -0.811 70.013 -91.625 1.00 28.26 ? 231 GLU A CG 1 ATOM 1880 C CD . GLU A 1 231 ? -0.288 71.359 -92.085 1.00 35.74 ? 231 GLU A CD 1 ATOM 1881 O OE1 . GLU A 1 231 ? -0.033 71.578 -93.299 1.00 34.36 ? 231 GLU A OE1 1 ATOM 1882 O OE2 . GLU A 1 231 ? -0.177 72.250 -91.199 1.00 32.09 ? 231 GLU A OE2 1 ATOM 1883 N N . PHE A 1 232 ? -3.094 67.287 -90.724 1.00 21.81 ? 232 PHE A N 1 ATOM 1884 C CA . PHE A 1 232 ? -4.497 67.119 -90.406 1.00 23.53 ? 232 PHE A CA 1 ATOM 1885 C C . PHE A 1 232 ? -5.042 68.340 -89.704 1.00 29.09 ? 232 PHE A C 1 ATOM 1886 O O . PHE A 1 232 ? -4.302 69.029 -88.978 1.00 24.56 ? 232 PHE A O 1 ATOM 1887 C CB . PHE A 1 232 ? -4.687 65.887 -89.554 1.00 23.68 ? 232 PHE A CB 1 ATOM 1888 C CG . PHE A 1 232 ? -4.348 64.631 -90.308 1.00 24.04 ? 232 PHE A CG 1 ATOM 1889 C CD1 . PHE A 1 232 ? -3.103 64.017 -90.162 1.00 24.48 ? 232 PHE A CD1 1 ATOM 1890 C CD2 . PHE A 1 232 ? -5.250 64.125 -91.229 1.00 26.45 ? 232 PHE A CD2 1 ATOM 1891 C CE1 . PHE A 1 232 ? -2.794 62.857 -90.889 1.00 29.36 ? 232 PHE A CE1 1 ATOM 1892 C CE2 . PHE A 1 232 ? -4.920 62.963 -91.983 1.00 24.30 ? 232 PHE A CE2 1 ATOM 1893 C CZ . PHE A 1 232 ? -3.699 62.349 -91.800 1.00 30.73 ? 232 PHE A CZ 1 ATOM 1894 N N . PHE A 1 233 ? -6.317 68.576 -89.935 1.00 21.78 ? 233 PHE A N 1 ATOM 1895 C CA . PHE A 1 233 ? -7.070 69.711 -89.401 1.00 25.70 ? 233 PHE A CA 1 ATOM 1896 C C . PHE A 1 233 ? -8.381 69.254 -88.794 1.00 26.73 ? 233 PHE A C 1 ATOM 1897 O O . PHE A 1 233 ? -8.889 68.173 -89.127 1.00 24.26 ? 233 PHE A O 1 ATOM 1898 C CB . PHE A 1 233 ? -7.386 70.721 -90.506 1.00 24.29 ? 233 PHE A CB 1 ATOM 1899 C CG . PHE A 1 233 ? -6.149 71.352 -91.074 1.00 26.54 ? 233 PHE A CG 1 ATOM 1900 C CD1 . PHE A 1 233 ? -5.372 70.643 -92.027 1.00 28.26 ? 233 PHE A CD1 1 ATOM 1901 C CD2 . PHE A 1 233 ? -5.693 72.585 -90.593 1.00 28.41 ? 233 PHE A CD2 1 ATOM 1902 C CE1 . PHE A 1 233 ? -4.157 71.180 -92.534 1.00 29.42 ? 233 PHE A CE1 1 ATOM 1903 C CE2 . PHE A 1 233 ? -4.491 73.130 -91.091 1.00 32.07 ? 233 PHE A CE2 1 ATOM 1904 C CZ . PHE A 1 233 ? -3.728 72.438 -92.069 1.00 30.57 ? 233 PHE A CZ 1 ATOM 1905 N N . TRP A 1 234 ? -8.987 70.080 -87.950 1.00 21.94 ? 234 TRP A N 1 ATOM 1906 C CA . TRP A 1 234 ? -10.254 69.678 -87.326 1.00 20.52 ? 234 TRP A CA 1 ATOM 1907 C C . TRP A 1 234 ? -11.071 70.887 -87.026 1.00 24.95 ? 234 TRP A C 1 ATOM 1908 O O . TRP A 1 234 ? -10.518 72.008 -86.927 1.00 23.75 ? 234 TRP A O 1 ATOM 1909 C CB . TRP A 1 234 ? -10.002 68.902 -86.048 1.00 21.51 ? 234 TRP A CB 1 ATOM 1910 C CG . TRP A 1 234 ? -9.225 69.715 -84.980 1.00 21.85 ? 234 TRP A CG 1 ATOM 1911 C CD1 . TRP A 1 234 ? -7.874 69.858 -84.892 1.00 25.67 ? 234 TRP A CD1 1 ATOM 1912 C CD2 . TRP A 1 234 ? -9.786 70.486 -83.922 1.00 21.67 ? 234 TRP A CD2 1 ATOM 1913 N NE1 . TRP A 1 234 ? -7.546 70.663 -83.813 1.00 23.89 ? 234 TRP A NE1 1 ATOM 1914 C CE2 . TRP A 1 234 ? -8.710 71.065 -83.207 1.00 22.49 ? 234 TRP A CE2 1 ATOM 1915 C CE3 . TRP A 1 234 ? -11.103 70.741 -83.498 1.00 20.20 ? 234 TRP A CE3 1 ATOM 1916 C CZ2 . TRP A 1 234 ? -8.905 71.888 -82.097 1.00 22.83 ? 234 TRP A CZ2 1 ATOM 1917 C CZ3 . TRP A 1 234 ? -11.315 71.593 -82.407 1.00 22.86 ? 234 TRP A CZ3 1 ATOM 1918 C CH2 . TRP A 1 234 ? -10.198 72.148 -81.705 1.00 23.26 ? 234 TRP A CH2 1 ATOM 1919 N N . THR A 1 235 ? -12.369 70.663 -86.897 1.00 21.28 ? 235 THR A N 1 ATOM 1920 C CA . THR A 1 235 ? -13.277 71.699 -86.405 1.00 18.31 ? 235 THR A CA 1 ATOM 1921 C C . THR A 1 235 ? -14.425 71.082 -85.651 1.00 21.84 ? 235 THR A C 1 ATOM 1922 O O . THR A 1 235 ? -14.671 69.863 -85.714 1.00 22.53 ? 235 THR A O 1 ATOM 1923 C CB . THR A 1 235 ? -13.793 72.609 -87.588 1.00 22.30 ? 235 THR A CB 1 ATOM 1924 O OG1 . THR A 1 235 ? -14.419 73.782 -87.040 1.00 25.60 ? 235 THR A OG1 1 ATOM 1925 C CG2 . THR A 1 235 ? -14.831 71.841 -88.425 1.00 24.45 ? 235 THR A CG2 1 ATOM 1926 N N . ILE A 1 236 ? -15.122 71.894 -84.863 1.00 20.04 ? 236 ILE A N 1 ATOM 1927 C CA . ILE A 1 236 ? -16.334 71.441 -84.262 1.00 22.24 ? 236 ILE A CA 1 ATOM 1928 C C . ILE A 1 236 ? -17.502 72.031 -85.063 1.00 28.79 ? 236 ILE A C 1 ATOM 1929 O O . ILE A 1 236 ? -17.625 73.271 -85.206 1.00 25.88 ? 236 ILE A O 1 ATOM 1930 C CB . ILE A 1 236 ? -16.448 71.942 -82.774 1.00 22.39 ? 236 ILE A CB 1 ATOM 1931 C CG1 . ILE A 1 236 ? -15.340 71.333 -81.904 1.00 26.78 ? 236 ILE A CG1 1 ATOM 1932 C CG2 . ILE A 1 236 ? -17.846 71.637 -82.237 1.00 24.54 ? 236 ILE A CG2 1 ATOM 1933 C CD1 . ILE A 1 236 ? -15.352 69.821 -81.836 1.00 26.66 ? 236 ILE A CD1 1 ATOM 1934 N N . LEU A 1 237 ? -18.361 71.155 -85.587 1.00 23.12 ? 237 LEU A N 1 ATOM 1935 C CA . LEU A 1 237 ? -19.463 71.582 -86.458 1.00 23.38 ? 237 LEU A CA 1 ATOM 1936 C C . LEU A 1 237 ? -20.712 71.599 -85.596 1.00 26.71 ? 237 LEU A C 1 ATOM 1937 O O . LEU A 1 237 ? -21.178 70.565 -85.076 1.00 23.50 ? 237 LEU A O 1 ATOM 1938 C CB . LEU A 1 237 ? -19.582 70.627 -87.707 1.00 21.12 ? 237 LEU A CB 1 ATOM 1939 C CG . LEU A 1 237 ? -20.681 70.998 -88.696 1.00 21.94 ? 237 LEU A CG 1 ATOM 1940 C CD1 . LEU A 1 237 ? -20.341 72.336 -89.374 1.00 24.36 ? 237 LEU A CD1 1 ATOM 1941 C CD2 . LEU A 1 237 ? -20.730 69.902 -89.810 1.00 25.14 ? 237 LEU A CD2 1 ATOM 1942 N N . LYS A 1 238 ? -21.260 72.804 -85.378 1.00 22.14 ? 238 LYS A N 1 ATOM 1943 C CA . LYS A 1 238 ? -22.391 72.894 -84.482 1.00 23.35 ? 238 LYS A CA 1 ATOM 1944 C C . LYS A 1 238 ? -23.677 72.334 -85.097 1.00 24.64 ? 238 LYS A C 1 ATOM 1945 O O . LYS A 1 238 ? -23.783 72.203 -86.339 1.00 29.58 ? 238 LYS A O 1 ATOM 1946 C CB . LYS A 1 238 ? -22.597 74.374 -84.066 1.00 28.37 ? 238 LYS A CB 1 ATOM 1947 C CG . LYS A 1 238 ? -21.423 74.909 -83.250 1.00 37.33 ? 238 LYS A CG 1 ATOM 1948 C CD . LYS A 1 238 ? -21.783 76.243 -82.636 1.00 53.55 ? 238 LYS A CD 1 ATOM 1949 C CE . LYS A 1 238 ? -20.823 76.647 -81.517 1.00 58.14 ? 238 LYS A CE 1 ATOM 1950 N NZ . LYS A 1 238 ? -20.969 78.117 -81.181 1.00 68.51 ? 238 LYS A NZ 1 ATOM 1951 N N . PRO A 1 239 ? -24.623 71.987 -84.238 1.00 26.70 ? 239 PRO A N 1 ATOM 1952 C CA . PRO A 1 239 ? -25.911 71.507 -84.742 1.00 28.01 ? 239 PRO A CA 1 ATOM 1953 C C . PRO A 1 239 ? -26.525 72.470 -85.772 1.00 36.10 ? 239 PRO A C 1 ATOM 1954 O O . PRO A 1 239 ? -26.520 73.691 -85.582 1.00 30.64 ? 239 PRO A O 1 ATOM 1955 C CB . PRO A 1 239 ? -26.757 71.429 -83.488 1.00 31.42 ? 239 PRO A CB 1 ATOM 1956 C CG . PRO A 1 239 ? -25.747 71.105 -82.392 1.00 32.17 ? 239 PRO A CG 1 ATOM 1957 C CD . PRO A 1 239 ? -24.564 71.951 -82.758 1.00 30.09 ? 239 PRO A CD 1 ATOM 1958 N N . ASN A 1 240 ? -27.003 71.903 -86.877 1.00 32.09 ? 240 ASN A N 1 ATOM 1959 C CA . ASN A 1 240 ? -27.633 72.655 -87.960 1.00 32.71 ? 240 ASN A CA 1 ATOM 1960 C C . ASN A 1 240 ? -26.714 73.496 -88.840 1.00 33.62 ? 240 ASN A C 1 ATOM 1961 O O . ASN A 1 240 ? -27.160 74.138 -89.790 1.00 35.53 ? 240 ASN A O 1 ATOM 1962 C CB . ASN A 1 240 ? -28.801 73.499 -87.415 1.00 43.78 ? 240 ASN A CB 1 ATOM 1963 C CG . ASN A 1 240 ? -29.944 73.626 -88.414 1.00 61.26 ? 240 ASN A CG 1 ATOM 1964 O OD1 . ASN A 1 240 ? -30.403 72.621 -88.983 1.00 56.75 ? 240 ASN A OD1 1 ATOM 1965 N ND2 . ASN A 1 240 ? -30.402 74.872 -88.649 1.00 53.50 ? 240 ASN A ND2 1 ATOM 1966 N N . ASP A 1 241 ? -25.418 73.493 -88.556 1.00 25.21 ? 241 ASP A N 1 ATOM 1967 C CA . ASP A 1 241 ? -24.455 74.071 -89.460 1.00 27.12 ? 241 ASP A CA 1 ATOM 1968 C C . ASP A 1 241 ? -24.025 73.012 -90.483 1.00 31.92 ? 241 ASP A C 1 ATOM 1969 O O . ASP A 1 241 ? -24.293 71.799 -90.326 1.00 34.05 ? 241 ASP A O 1 ATOM 1970 C CB . ASP A 1 241 ? -23.214 74.637 -88.681 1.00 26.21 ? 241 ASP A CB 1 ATOM 1971 C CG . ASP A 1 241 ? -22.439 75.683 -89.474 1.00 25.74 ? 241 ASP A CG 1 ATOM 1972 O OD1 . ASP A 1 241 ? -22.916 76.161 -90.552 1.00 29.85 ? 241 ASP A OD1 1 ATOM 1973 O OD2 . ASP A 1 241 ? -21.303 76.076 -89.069 1.00 27.69 ? 241 ASP A OD2 1 ATOM 1974 N N . ALA A 1 242 ? -23.358 73.477 -91.508 1.00 28.42 ? 242 ALA A N 1 ATOM 1975 C CA . ALA A 1 242 ? -22.813 72.589 -92.561 1.00 28.29 ? 242 ALA A CA 1 ATOM 1976 C C . ALA A 1 242 ? -21.374 72.897 -92.854 1.00 30.44 ? 242 ALA A C 1 ATOM 1977 O O . ALA A 1 242 ? -20.911 74.067 -92.754 1.00 29.02 ? 242 ALA A O 1 ATOM 1978 C CB . ALA A 1 242 ? -23.662 72.698 -93.854 1.00 29.82 ? 242 ALA A CB 1 ATOM 1979 N N . ILE A 1 243 ? -20.643 71.856 -93.250 1.00 23.53 ? 243 ILE A N 1 ATOM 1980 C CA . ILE A 1 243 ? -19.280 72.007 -93.701 1.00 23.85 ? 243 ILE A CA 1 ATOM 1981 C C . ILE A 1 243 ? -19.174 71.719 -95.197 1.00 34.30 ? 243 ILE A C 1 ATOM 1982 O O . ILE A 1 243 ? -19.773 70.737 -95.714 1.00 31.56 ? 243 ILE A O 1 ATOM 1983 C CB . ILE A 1 243 ? -18.354 71.095 -92.851 1.00 25.64 ? 243 ILE A CB 1 ATOM 1984 C CG1 . ILE A 1 243 ? -16.894 71.377 -93.186 1.00 23.14 ? 243 ILE A CG1 1 ATOM 1985 C CG2 . ILE A 1 243 ? -18.729 69.583 -93.083 1.00 29.22 ? 243 ILE A CG2 1 ATOM 1986 C CD1 . ILE A 1 243 ? -15.928 70.977 -91.986 1.00 23.64 ? 243 ILE A CD1 1 ATOM 1987 N N . ASN A 1 244 ? -18.467 72.600 -95.890 1.00 25.08 ? 244 ASN A N 1 ATOM 1988 C CA . ASN A 1 244 ? -18.298 72.490 -97.328 1.00 30.67 ? 244 ASN A CA 1 ATOM 1989 C C . ASN A 1 244 ? -16.870 72.373 -97.715 1.00 34.04 ? 244 ASN A C 1 ATOM 1990 O O . ASN A 1 244 ? -16.067 73.259 -97.436 1.00 29.99 ? 244 ASN A O 1 ATOM 1991 C CB . ASN A 1 244 ? -18.929 73.687 -98.071 1.00 32.07 ? 244 ASN A CB 1 ATOM 1992 C CG . ASN A 1 244 ? -20.337 73.982 -97.598 1.00 30.86 ? 244 ASN A CG 1 ATOM 1993 O OD1 . ASN A 1 244 ? -21.292 73.235 -97.874 1.00 43.73 ? 244 ASN A OD1 1 ATOM 1994 N ND2 . ASN A 1 244 ? -20.486 75.046 -96.885 1.00 36.67 ? 244 ASN A ND2 1 ATOM 1995 N N . PHE A 1 245 ? -16.550 71.263 -98.382 1.00 26.25 ? 245 PHE A N 1 ATOM 1996 C CA . PHE A 1 245 ? -15.219 70.970 -98.866 1.00 25.13 ? 245 PHE A CA 1 ATOM 1997 C C . PHE A 1 245 ? -15.155 71.203 -100.379 1.00 28.70 ? 245 PHE A C 1 ATOM 1998 O O . PHE A 1 245 ? -16.104 70.830 -101.104 1.00 31.18 ? 245 PHE A O 1 ATOM 1999 C CB . PHE A 1 245 ? -14.871 69.502 -98.598 1.00 27.18 ? 245 PHE A CB 1 ATOM 2000 C CG . PHE A 1 245 ? -14.757 69.152 -97.120 1.00 26.96 ? 245 PHE A CG 1 ATOM 2001 C CD1 . PHE A 1 245 ? -15.815 68.565 -96.450 1.00 29.34 ? 245 PHE A CD1 1 ATOM 2002 C CD2 . PHE A 1 245 ? -13.560 69.401 -96.444 1.00 27.36 ? 245 PHE A CD2 1 ATOM 2003 C CE1 . PHE A 1 245 ? -15.709 68.212 -95.083 1.00 27.71 ? 245 PHE A CE1 1 ATOM 2004 C CE2 . PHE A 1 245 ? -13.438 69.073 -95.086 1.00 28.50 ? 245 PHE A CE2 1 ATOM 2005 C CZ . PHE A 1 245 ? -14.545 68.480 -94.390 1.00 26.98 ? 245 PHE A CZ 1 ATOM 2006 N N . GLU A 1 246 ? -14.055 71.797 -100.847 1.00 30.27 ? 246 GLU A N 1 ATOM 2007 C CA . GLU A 1 246 ? -13.753 71.863 -102.282 1.00 31.67 ? 246 GLU A CA 1 ATOM 2008 C C . GLU A 1 246 ? -12.271 71.621 -102.526 1.00 33.42 ? 246 GLU A C 1 ATOM 2009 O O . GLU A 1 246 ? -11.414 72.170 -101.815 1.00 31.68 ? 246 GLU A O 1 ATOM 2010 C CB . GLU A 1 246 ? -14.161 73.225 -102.882 1.00 30.87 ? 246 GLU A CB 1 ATOM 2011 C CG . GLU A 1 246 ? -13.974 73.210 -104.424 1.00 37.78 ? 246 GLU A CG 1 ATOM 2012 C CD . GLU A 1 246 ? -14.328 74.537 -105.094 1.00 38.70 ? 246 GLU A CD 1 ATOM 2013 O OE1 . GLU A 1 246 ? -13.406 75.140 -105.702 1.00 41.35 ? 246 GLU A OE1 1 ATOM 2014 O OE2 . GLU A 1 246 ? -15.518 74.928 -105.024 1.00 44.46 ? 246 GLU A OE2 1 ATOM 2015 N N . SER A 1 247 ? -11.932 70.786 -103.502 1.00 28.78 ? 247 SER A N 1 ATOM 2016 C CA . SER A 1 247 ? -10.519 70.511 -103.771 1.00 29.05 ? 247 SER A CA 1 ATOM 2017 C C . SER A 1 247 ? -10.306 69.910 -105.175 1.00 32.57 ? 247 SER A C 1 ATOM 2018 O O . SER A 1 247 ? -11.160 69.154 -105.682 1.00 32.57 ? 247 SER A O 1 ATOM 2019 C CB . SER A 1 247 ? -9.974 69.531 -102.738 1.00 26.26 ? 247 SER A CB 1 ATOM 2020 O OG . SER A 1 247 ? -8.664 69.135 -103.017 1.00 29.69 ? 247 SER A OG 1 ATOM 2021 N N . ASN A 1 248 ? -9.149 70.202 -105.760 1.00 29.73 ? 248 ASN A N 1 ATOM 2022 C CA . ASN A 1 248 ? -8.780 69.603 -107.049 1.00 33.67 ? 248 ASN A CA 1 ATOM 2023 C C . ASN A 1 248 ? -7.509 68.820 -106.830 1.00 34.46 ? 248 ASN A C 1 ATOM 2024 O O . ASN A 1 248 ? -6.749 68.578 -107.759 1.00 35.02 ? 248 ASN A O 1 ATOM 2025 C CB . ASN A 1 248 ? -8.577 70.700 -108.129 1.00 32.97 ? 248 ASN A CB 1 ATOM 2026 C CG . ASN A 1 248 ? -7.385 71.582 -107.823 1.00 39.00 ? 248 ASN A CG 1 ATOM 2027 O OD1 . ASN A 1 248 ? -7.006 71.722 -106.665 1.00 34.33 ? 248 ASN A OD1 1 ATOM 2028 N ND2 . ASN A 1 248 ? -6.794 72.194 -108.858 1.00 36.55 ? 248 ASN A ND2 1 ATOM 2029 N N . GLY A 1 249 ? -7.287 68.359 -105.590 1.00 32.33 ? 249 GLY A N 1 ATOM 2030 C CA . GLY A 1 249 ? -6.170 67.460 -105.325 1.00 29.61 ? 249 GLY A CA 1 ATOM 2031 C C . GLY A 1 249 ? -5.642 67.509 -103.893 1.00 29.13 ? 249 GLY A C 1 ATOM 2032 O O . GLY A 1 249 ? -5.904 68.491 -103.210 1.00 31.49 ? 249 GLY A O 1 ATOM 2033 N N . ASN A 1 250 ? -4.909 66.469 -103.495 1.00 28.39 ? 250 ASN A N 1 ATOM 2034 C CA . ASN A 1 250 ? -4.177 66.358 -102.239 1.00 26.08 ? 250 ASN A CA 1 ATOM 2035 C C . ASN A 1 250 ? -5.100 66.263 -100.990 1.00 28.81 ? 250 ASN A C 1 ATOM 2036 O O . ASN A 1 250 ? -4.614 66.334 -99.832 1.00 29.59 ? 250 ASN A O 1 ATOM 2037 C CB . ASN A 1 250 ? -3.186 67.529 -102.070 1.00 27.92 ? 250 ASN A CB 1 ATOM 2038 C CG . ASN A 1 250 ? -2.304 67.733 -103.298 1.00 30.13 ? 250 ASN A CG 1 ATOM 2039 O OD1 . ASN A 1 250 ? -2.783 68.084 -104.381 1.00 29.13 ? 250 ASN A OD1 1 ATOM 2040 N ND2 . ASN A 1 250 ? -1.030 67.534 -103.124 1.00 27.82 ? 250 ASN A ND2 1 ATOM 2041 N N . PHE A 1 251 ? -6.395 66.081 -101.239 1.00 25.87 ? 251 PHE A N 1 ATOM 2042 C CA . PHE A 1 251 ? -7.451 66.100 -100.187 1.00 26.24 ? 251 PHE A CA 1 ATOM 2043 C C . PHE A 1 251 ? -7.521 64.756 -99.461 1.00 31.67 ? 251 PHE A C 1 ATOM 2044 O O . PHE A 1 251 ? -7.653 63.710 -100.118 1.00 27.18 ? 251 PHE A O 1 ATOM 2045 C CB . PHE A 1 251 ? -8.766 66.478 -100.860 1.00 30.94 ? 251 PHE A CB 1 ATOM 2046 C CG . PHE A 1 251 ? -9.956 66.546 -99.954 1.00 26.47 ? 251 PHE A CG 1 ATOM 2047 C CD1 . PHE A 1 251 ? -9.842 67.042 -98.652 1.00 27.95 ? 251 PHE A CD1 1 ATOM 2048 C CD2 . PHE A 1 251 ? -11.226 66.218 -100.431 1.00 27.06 ? 251 PHE A CD2 1 ATOM 2049 C CE1 . PHE A 1 251 ? -10.985 67.144 -97.843 1.00 26.72 ? 251 PHE A CE1 1 ATOM 2050 C CE2 . PHE A 1 251 ? -12.366 66.339 -99.649 1.00 22.84 ? 251 PHE A CE2 1 ATOM 2051 C CZ . PHE A 1 251 ? -12.254 66.801 -98.337 1.00 26.33 ? 251 PHE A CZ 1 ATOM 2052 N N . ILE A 1 252 ? -7.340 64.760 -98.134 1.00 26.52 ? 252 ILE A N 1 ATOM 2053 C CA . ILE A 1 252 ? -7.553 63.568 -97.312 1.00 26.37 ? 252 ILE A CA 1 ATOM 2054 C C . ILE A 1 252 ? -8.921 63.784 -96.693 1.00 27.12 ? 252 ILE A C 1 ATOM 2055 O O . ILE A 1 252 ? -9.079 64.573 -95.758 1.00 27.03 ? 252 ILE A O 1 ATOM 2056 C CB . ILE A 1 252 ? -6.426 63.368 -96.235 1.00 23.48 ? 252 ILE A CB 1 ATOM 2057 C CG1 . ILE A 1 252 ? -5.049 63.609 -96.870 1.00 26.97 ? 252 ILE A CG1 1 ATOM 2058 C CG2 . ILE A 1 252 ? -6.477 61.944 -95.652 1.00 23.75 ? 252 ILE A CG2 1 ATOM 2059 C CD1 . ILE A 1 252 ? -4.792 62.664 -98.109 1.00 25.59 ? 252 ILE A CD1 1 ATOM 2060 N N . ALA A 1 253 ? -9.963 63.144 -97.275 1.00 24.20 ? 253 ALA A N 1 ATOM 2061 C CA . ALA A 1 253 ? -11.334 63.491 -96.987 1.00 21.77 ? 253 ALA A CA 1 ATOM 2062 C C . ALA A 1 253 ? -11.885 62.774 -95.744 1.00 21.57 ? 253 ALA A C 1 ATOM 2063 O O . ALA A 1 253 ? -11.464 61.685 -95.442 1.00 23.13 ? 253 ALA A O 1 ATOM 2064 C CB . ALA A 1 253 ? -12.220 63.063 -98.247 1.00 24.78 ? 253 ALA A CB 1 ATOM 2065 N N . PRO A 1 254 ? -12.831 63.386 -95.037 1.00 22.72 ? 254 PRO A N 1 ATOM 2066 C CA . PRO A 1 254 ? -13.506 62.677 -93.951 1.00 21.22 ? 254 PRO A CA 1 ATOM 2067 C C . PRO A 1 254 ? -14.176 61.419 -94.458 1.00 26.06 ? 254 PRO A C 1 ATOM 2068 O O . PRO A 1 254 ? -14.665 61.458 -95.580 1.00 24.83 ? 254 PRO A O 1 ATOM 2069 C CB . PRO A 1 254 ? -14.630 63.635 -93.541 1.00 25.27 ? 254 PRO A CB 1 ATOM 2070 C CG . PRO A 1 254 ? -14.087 65.023 -93.958 1.00 23.40 ? 254 PRO A CG 1 ATOM 2071 C CD . PRO A 1 254 ? -13.345 64.753 -95.245 1.00 24.52 ? 254 PRO A CD 1 ATOM 2072 N N . GLU A 1 255 ? -14.178 60.356 -93.669 1.00 24.73 ? 255 GLU A N 1 ATOM 2073 C CA . GLU A 1 255 ? -15.203 59.325 -93.805 1.00 25.68 ? 255 GLU A CA 1 ATOM 2074 C C . GLU A 1 255 ? -16.024 59.338 -92.520 1.00 23.20 ? 255 GLU A C 1 ATOM 2075 O O . GLU A 1 255 ? -17.227 59.528 -92.564 1.00 22.64 ? 255 GLU A O 1 ATOM 2076 C CB . GLU A 1 255 ? -14.655 57.897 -94.096 1.00 22.07 ? 255 GLU A CB 1 ATOM 2077 C CG . GLU A 1 255 ? -15.882 56.914 -94.004 1.00 28.87 ? 255 GLU A CG 1 ATOM 2078 C CD . GLU A 1 255 ? -15.692 55.510 -94.644 1.00 30.91 ? 255 GLU A CD 1 ATOM 2079 O OE1 . GLU A 1 255 ? -14.544 55.052 -94.636 1.00 31.97 ? 255 GLU A OE1 1 ATOM 2080 O OE2 . GLU A 1 255 ? -16.739 54.882 -95.069 1.00 34.67 ? 255 GLU A OE2 1 ATOM 2081 N N . TYR A 1 256 ? -15.344 59.218 -91.375 1.00 20.62 ? 256 TYR A N 1 ATOM 2082 C CA . TYR A 1 256 ? -16.027 59.196 -90.081 1.00 18.66 ? 256 TYR A CA 1 ATOM 2083 C C . TYR A 1 256 ? -15.716 60.481 -89.293 1.00 21.95 ? 256 TYR A C 1 ATOM 2084 O O . TYR A 1 256 ? -14.611 61.020 -89.422 1.00 22.51 ? 256 TYR A O 1 ATOM 2085 C CB . TYR A 1 256 ? -15.506 58.048 -89.252 1.00 19.65 ? 256 TYR A CB 1 ATOM 2086 C CG . TYR A 1 256 ? -15.987 56.712 -89.848 1.00 19.55 ? 256 TYR A CG 1 ATOM 2087 C CD1 . TYR A 1 256 ? -15.106 55.828 -90.453 1.00 28.79 ? 256 TYR A CD1 1 ATOM 2088 C CD2 . TYR A 1 256 ? -17.310 56.402 -89.748 1.00 22.36 ? 256 TYR A CD2 1 ATOM 2089 C CE1 . TYR A 1 256 ? -15.567 54.623 -90.985 1.00 27.44 ? 256 TYR A CE1 1 ATOM 2090 C CE2 . TYR A 1 256 ? -17.814 55.184 -90.311 1.00 25.72 ? 256 TYR A CE2 1 ATOM 2091 C CZ . TYR A 1 256 ? -16.928 54.314 -90.889 1.00 30.09 ? 256 TYR A CZ 1 ATOM 2092 O OH . TYR A 1 256 ? -17.427 53.116 -91.386 1.00 29.78 ? 256 TYR A OH 1 ATOM 2093 N N . ALA A 1 257 ? -16.720 60.938 -88.565 1.00 23.55 ? 257 ALA A N 1 ATOM 2094 C CA . ALA A 1 257 ? -16.555 62.068 -87.614 1.00 23.60 ? 257 ALA A CA 1 ATOM 2095 C C . ALA A 1 257 ? -17.094 61.639 -86.280 1.00 26.14 ? 257 ALA A C 1 ATOM 2096 O O . ALA A 1 257 ? -17.720 60.599 -86.164 1.00 24.91 ? 257 ALA A O 1 ATOM 2097 C CB . ALA A 1 257 ? -17.338 63.249 -88.079 1.00 23.68 ? 257 ALA A CB 1 ATOM 2098 N N . TYR A 1 258 ? -16.926 62.478 -85.242 1.00 21.09 ? 258 TYR A N 1 ATOM 2099 C CA . TYR A 1 258 ? -17.284 62.030 -83.923 1.00 24.07 ? 258 TYR A CA 1 ATOM 2100 C C . TYR A 1 258 ? -18.344 62.942 -83.295 1.00 25.43 ? 258 TYR A C 1 ATOM 2101 O O . TYR A 1 258 ? -18.082 64.149 -83.010 1.00 25.37 ? 258 TYR A O 1 ATOM 2102 C CB . TYR A 1 258 ? -16.038 62.050 -83.032 1.00 21.41 ? 258 TYR A CB 1 ATOM 2103 C CG . TYR A 1 258 ? -15.028 60.987 -83.357 1.00 23.37 ? 258 TYR A CG 1 ATOM 2104 C CD1 . TYR A 1 258 ? -13.952 61.262 -84.220 1.00 23.95 ? 258 TYR A CD1 1 ATOM 2105 C CD2 . TYR A 1 258 ? -15.146 59.730 -82.798 1.00 23.76 ? 258 TYR A CD2 1 ATOM 2106 C CE1 . TYR A 1 258 ? -13.028 60.276 -84.503 1.00 22.12 ? 258 TYR A CE1 1 ATOM 2107 C CE2 . TYR A 1 258 ? -14.208 58.739 -83.085 1.00 23.91 ? 258 TYR A CE2 1 ATOM 2108 C CZ . TYR A 1 258 ? -13.175 59.038 -83.927 1.00 23.20 ? 258 TYR A CZ 1 ATOM 2109 O OH . TYR A 1 258 ? -12.260 58.049 -84.181 1.00 32.53 ? 258 TYR A OH 1 ATOM 2110 N N . LYS A 1 259 ? -19.523 62.369 -83.085 1.00 20.86 ? 259 LYS A N 1 ATOM 2111 C CA . LYS A 1 259 ? -20.573 63.104 -82.418 1.00 19.94 ? 259 LYS A CA 1 ATOM 2112 C C . LYS A 1 259 ? -20.320 63.131 -80.891 1.00 24.82 ? 259 LYS A C 1 ATOM 2113 O O . LYS A 1 259 ? -20.075 62.120 -80.246 1.00 22.93 ? 259 LYS A O 1 ATOM 2114 C CB . LYS A 1 259 ? -21.923 62.455 -82.790 1.00 23.06 ? 259 LYS A CB 1 ATOM 2115 C CG . LYS A 1 259 ? -23.106 63.145 -82.289 1.00 35.15 ? 259 LYS A CG 1 ATOM 2116 C CD . LYS A 1 259 ? -24.315 62.700 -83.150 1.00 40.80 ? 259 LYS A CD 1 ATOM 2117 C CE . LYS A 1 259 ? -24.451 61.186 -83.216 1.00 31.37 ? 259 LYS A CE 1 ATOM 2118 N NZ . LYS A 1 259 ? -25.833 60.698 -83.763 1.00 33.59 ? 259 LYS A NZ 1 ATOM 2119 N N . ILE A 1 260 ? -20.303 64.332 -80.300 1.00 21.33 ? 260 ILE A N 1 ATOM 2120 C CA . ILE A 1 260 ? -20.066 64.434 -78.853 1.00 22.70 ? 260 ILE A CA 1 ATOM 2121 C C . ILE A 1 260 ? -21.337 64.223 -78.085 1.00 27.37 ? 260 ILE A C 1 ATOM 2122 O O . ILE A 1 260 ? -22.198 65.085 -78.073 1.00 27.30 ? 260 ILE A O 1 ATOM 2123 C CB . ILE A 1 260 ? -19.462 65.845 -78.538 1.00 26.05 ? 260 ILE A CB 1 ATOM 2124 C CG1 . ILE A 1 260 ? -18.136 65.975 -79.304 1.00 26.14 ? 260 ILE A CG1 1 ATOM 2125 C CG2 . ILE A 1 260 ? -19.270 66.005 -77.026 1.00 25.97 ? 260 ILE A CG2 1 ATOM 2126 C CD1 . ILE A 1 260 ? -17.555 67.363 -79.442 1.00 38.26 ? 260 ILE A CD1 1 ATOM 2127 N N . VAL A 1 261 A -21.484 63.053 -77.451 1.00 22.31 ? 260 VAL A N 1 ATOM 2128 C CA . VAL A 1 261 A -22.739 62.667 -76.842 1.00 25.80 ? 260 VAL A CA 1 ATOM 2129 C C . VAL A 1 261 A -22.743 62.721 -75.331 1.00 31.31 ? 260 VAL A C 1 ATOM 2130 O O . VAL A 1 261 A -23.813 62.596 -74.706 1.00 26.69 ? 260 VAL A O 1 ATOM 2131 C CB . VAL A 1 261 A -23.241 61.259 -77.332 1.00 24.59 ? 260 VAL A CB 1 ATOM 2132 C CG1 . VAL A 1 261 A -23.542 61.296 -78.830 1.00 24.58 ? 260 VAL A CG1 1 ATOM 2133 C CG2 . VAL A 1 261 A -22.253 60.176 -77.029 1.00 26.82 ? 260 VAL A CG2 1 ATOM 2134 N N . LYS A 1 262 ? -21.572 62.863 -74.714 1.00 28.63 ? 261 LYS A N 1 ATOM 2135 C CA . LYS A 1 262 ? -21.528 63.030 -73.263 1.00 28.80 ? 261 LYS A CA 1 ATOM 2136 C C . LYS A 1 262 ? -20.368 63.980 -72.934 1.00 31.56 ? 261 LYS A C 1 ATOM 2137 O O . LYS A 1 262 ? -19.238 63.768 -73.389 1.00 26.73 ? 261 LYS A O 1 ATOM 2138 C CB . LYS A 1 262 ? -21.314 61.715 -72.510 1.00 27.76 ? 261 LYS A CB 1 ATOM 2139 C CG . LYS A 1 262 ? -21.463 61.973 -71.010 1.00 39.05 ? 261 LYS A CG 1 ATOM 2140 C CD . LYS A 1 262 ? -21.769 60.744 -70.193 1.00 43.34 ? 261 LYS A CD 1 ATOM 2141 C CE . LYS A 1 262 ? -21.739 61.095 -68.685 1.00 50.15 ? 261 LYS A CE 1 ATOM 2142 N NZ . LYS A 1 262 ? -22.265 59.985 -67.859 1.00 65.70 ? 261 LYS A NZ 1 ATOM 2143 N N . LYS A 1 263 ? -20.658 65.019 -72.154 1.00 32.57 ? 262 LYS A N 1 ATOM 2144 C CA . LYS A 1 263 ? -19.626 65.984 -71.739 1.00 33.44 ? 262 LYS A CA 1 ATOM 2145 C C . LYS A 1 263 ? -19.610 65.949 -70.219 1.00 36.89 ? 262 LYS A C 1 ATOM 2146 O O . LYS A 1 263 ? -20.633 65.657 -69.615 1.00 36.03 ? 262 LYS A O 1 ATOM 2147 C CB . LYS A 1 263 ? -20.015 67.387 -72.202 1.00 37.64 ? 262 LYS A CB 1 ATOM 2148 C CG . LYS A 1 263 ? -19.776 67.678 -73.663 1.00 43.08 ? 262 LYS A CG 1 ATOM 2149 C CD . LYS A 1 263 ? -20.455 69.007 -74.101 1.00 53.23 ? 262 LYS A CD 1 ATOM 2150 C CE . LYS A 1 263 ? -20.124 69.357 -75.566 1.00 66.65 ? 262 LYS A CE 1 ATOM 2151 N NZ . LYS A 1 263 ? -20.989 70.403 -76.204 1.00 62.14 ? 262 LYS A NZ 1 ATOM 2152 N N . GLY A 1 264 ? -18.473 66.244 -69.611 1.00 31.12 ? 263 GLY A N 1 ATOM 2153 C CA . GLY A 1 264 ? -18.316 66.070 -68.167 1.00 35.50 ? 263 GLY A CA 1 ATOM 2154 C C . GLY A 1 264 ? -16.870 66.268 -67.772 1.00 38.03 ? 263 GLY A C 1 ATOM 2155 O O . GLY A 1 264 ? -16.034 66.621 -68.592 1.00 39.64 ? 263 GLY A O 1 ATOM 2156 N N . ASP A 1 265 ? -16.574 66.046 -66.511 1.00 41.25 ? 264 ASP A N 1 ATOM 2157 C CA . ASP A 1 265 ? -15.204 66.067 -66.057 1.00 47.31 ? 264 ASP A CA 1 ATOM 2158 C C . ASP A 1 265 ? -14.458 64.886 -66.653 1.00 53.36 ? 264 ASP A C 1 ATOM 2159 O O . ASP A 1 265 ? -14.922 63.723 -66.610 1.00 35.67 ? 264 ASP A O 1 ATOM 2160 C CB . ASP A 1 265 ? -15.125 65.962 -64.543 1.00 54.95 ? 264 ASP A CB 1 ATOM 2161 C CG . ASP A 1 265 ? -15.718 67.159 -63.864 1.00 61.40 ? 264 ASP A CG 1 ATOM 2162 O OD1 . ASP A 1 265 ? -16.009 67.084 -62.642 1.00 86.24 ? 264 ASP A OD1 1 ATOM 2163 O OD2 . ASP A 1 265 ? -15.892 68.174 -64.579 1.00 51.77 ? 264 ASP A OD2 1 ATOM 2164 N N . SER A 1 266 ? -13.302 65.208 -67.215 1.00 37.40 ? 265 SER A N 1 ATOM 2165 C CA . SER A 1 266 ? -12.363 64.201 -67.601 1.00 32.48 ? 265 SER A CA 1 ATOM 2166 C C . SER A 1 266 ? -10.952 64.830 -67.587 1.00 38.95 ? 265 SER A C 1 ATOM 2167 O O . SER A 1 266 ? -10.753 66.000 -67.236 1.00 34.02 ? 265 SER A O 1 ATOM 2168 C CB . SER A 1 266 ? -12.727 63.655 -68.968 1.00 33.07 ? 265 SER A CB 1 ATOM 2169 O OG . SER A 1 266 ? -11.878 62.555 -69.303 1.00 34.40 ? 265 SER A OG 1 ATOM 2170 N N . THR A 1 267 ? -9.962 64.049 -67.954 1.00 28.32 ? 266 THR A N 1 ATOM 2171 C CA . THR A 1 267 ? -8.602 64.573 -68.020 1.00 24.06 ? 266 THR A CA 1 ATOM 2172 C C . THR A 1 267 ? -7.899 63.582 -68.890 1.00 30.24 ? 266 THR A C 1 ATOM 2173 O O . THR A 1 267 ? -8.398 62.456 -69.043 1.00 28.27 ? 266 THR A O 1 ATOM 2174 C CB . THR A 1 267 ? -7.899 64.631 -66.617 1.00 27.25 ? 266 THR A CB 1 ATOM 2175 O OG1 . THR A 1 267 ? -6.655 65.325 -66.785 1.00 28.24 ? 266 THR A OG1 1 ATOM 2176 C CG2 . THR A 1 267 ? -7.617 63.245 -66.070 1.00 28.67 ? 266 THR A CG2 1 ATOM 2177 N N . ILE A 1 268 ? -6.822 64.006 -69.524 1.00 24.03 ? 267 ILE A N 1 ATOM 2178 C CA . ILE A 1 268 ? -5.882 63.081 -70.132 1.00 20.77 ? 267 ILE A CA 1 ATOM 2179 C C . ILE A 1 268 ? -4.696 62.897 -69.179 1.00 27.71 ? 267 ILE A C 1 ATOM 2180 O O . ILE A 1 268 ? -3.867 63.787 -68.990 1.00 28.40 ? 267 ILE A O 1 ATOM 2181 C CB . ILE A 1 268 ? -5.361 63.580 -71.455 1.00 25.04 ? 267 ILE A CB 1 ATOM 2182 C CG1 . ILE A 1 268 ? -6.536 63.830 -72.385 1.00 26.33 ? 267 ILE A CG1 1 ATOM 2183 C CG2 . ILE A 1 268 ? -4.403 62.546 -72.094 1.00 28.37 ? 267 ILE A CG2 1 ATOM 2184 C CD1 . ILE A 1 268 ? -6.120 64.444 -73.724 1.00 27.35 ? 267 ILE A CD1 1 ATOM 2185 N N . MET A 1 269 ? -4.589 61.697 -68.641 1.00 24.67 ? 268 MET A N 1 ATOM 2186 C CA . MET A 1 269 ? -3.620 61.406 -67.597 1.00 21.08 ? 268 MET A CA 1 ATOM 2187 C C . MET A 1 269 ? -2.438 60.748 -68.257 1.00 27.59 ? 268 MET A C 1 ATOM 2188 O O . MET A 1 269 ? -2.611 59.834 -69.074 1.00 28.80 ? 268 MET A O 1 ATOM 2189 C CB . MET A 1 269 ? -4.269 60.484 -66.564 1.00 25.22 ? 268 MET A CB 1 ATOM 2190 C CG . MET A 1 269 ? -3.328 60.005 -65.446 1.00 28.99 ? 268 MET A CG 1 ATOM 2191 S SD . MET A 1 269 ? -4.300 59.020 -64.248 1.00 32.90 ? 268 MET A SD 1 ATOM 2192 C CE . MET A 1 269 ? -5.283 60.277 -63.512 1.00 29.89 ? 268 MET A CE 1 ATOM 2193 N N . LYS A 1 270 ? -1.230 61.224 -67.958 1.00 27.90 ? 269 LYS A N 1 ATOM 2194 C CA . LYS A 1 270 ? -0.035 60.633 -68.537 1.00 24.71 ? 269 LYS A CA 1 ATOM 2195 C C . LYS A 1 270 ? 0.489 59.552 -67.591 1.00 32.90 ? 269 LYS A C 1 ATOM 2196 O O . LYS A 1 270 ? 0.825 59.853 -66.457 1.00 31.03 ? 269 LYS A O 1 ATOM 2197 C CB . LYS A 1 270 ? 1.033 61.710 -68.779 1.00 27.47 ? 269 LYS A CB 1 ATOM 2198 C CG . LYS A 1 270 ? 0.719 62.724 -69.854 1.00 29.87 ? 269 LYS A CG 1 ATOM 2199 C CD . LYS A 1 270 ? 0.533 62.005 -71.255 1.00 36.02 ? 269 LYS A CD 1 ATOM 2200 C CE . LYS A 1 270 ? 1.331 62.659 -72.427 1.00 47.15 ? 269 LYS A CE 1 ATOM 2201 N NZ . LYS A 1 270 ? 1.392 61.871 -73.790 1.00 34.14 ? 269 LYS A NZ 1 ATOM 2202 N N . SER A 1 271 ? 0.526 58.291 -68.027 1.00 28.52 ? 270 SER A N 1 ATOM 2203 C CA . SER A 1 271 ? 0.951 57.193 -67.169 1.00 26.07 ? 270 SER A CA 1 ATOM 2204 C C . SER A 1 271 ? 1.395 56.035 -68.032 1.00 37.29 ? 270 SER A C 1 ATOM 2205 O O . SER A 1 271 ? 0.857 55.854 -69.115 1.00 29.18 ? 270 SER A O 1 ATOM 2206 C CB . SER A 1 271 ? -0.184 56.734 -66.270 1.00 28.69 ? 270 SER A CB 1 ATOM 2207 O OG . SER A 1 271 ? 0.269 55.709 -65.385 1.00 31.62 ? 270 SER A OG 1 ATOM 2208 N N . GLU A 1 272 ? 2.360 55.252 -67.552 1.00 29.01 ? 271 GLU A N 1 ATOM 2209 C CA . GLU A 1 272 ? 2.803 54.072 -68.299 1.00 35.96 ? 271 GLU A CA 1 ATOM 2210 C C . GLU A 1 272 ? 2.082 52.827 -67.842 1.00 31.59 ? 271 GLU A C 1 ATOM 2211 O O . GLU A 1 272 ? 2.248 51.743 -68.418 1.00 33.66 ? 271 GLU A O 1 ATOM 2212 C CB . GLU A 1 272 ? 4.311 53.848 -68.128 1.00 38.17 ? 271 GLU A CB 1 ATOM 2213 C CG . GLU A 1 272 ? 5.182 55.013 -68.557 1.00 39.07 ? 271 GLU A CG 1 ATOM 2214 C CD . GLU A 1 272 ? 4.889 55.522 -69.977 1.00 39.06 ? 271 GLU A CD 1 ATOM 2215 O OE1 . GLU A 1 272 ? 5.079 54.762 -70.969 1.00 37.42 ? 271 GLU A OE1 1 ATOM 2216 O OE2 . GLU A 1 272 ? 4.511 56.714 -70.100 1.00 33.71 ? 271 GLU A OE2 1 ATOM 2217 N N . LEU A 1 273 ? 1.286 52.958 -66.799 1.00 29.01 ? 272 LEU A N 1 ATOM 2218 C CA . LEU A 1 273 ? 0.556 51.833 -66.244 1.00 28.61 ? 272 LEU A CA 1 ATOM 2219 C C . LEU A 1 273 ? -0.603 51.422 -67.162 1.00 34.80 ? 272 LEU A C 1 ATOM 2220 O O . LEU A 1 273 ? -1.056 52.188 -67.976 1.00 35.55 ? 272 LEU A O 1 ATOM 2221 C CB . LEU A 1 273 ? -0.002 52.159 -64.867 1.00 32.86 ? 272 LEU A CB 1 ATOM 2222 C CG . LEU A 1 273 ? 1.070 52.526 -63.822 1.00 33.67 ? 272 LEU A CG 1 ATOM 2223 C CD1 . LEU A 1 273 ? 0.404 52.938 -62.548 1.00 29.86 ? 272 LEU A CD1 1 ATOM 2224 C CD2 . LEU A 1 273 ? 2.082 51.340 -63.553 1.00 34.92 ? 272 LEU A CD2 1 ATOM 2225 N N . GLU A 1 274 ? -1.119 50.224 -66.966 1.00 42.00 ? 273 GLU A N 1 ATOM 2226 C CA . GLU A 1 274 ? -2.330 49.850 -67.691 1.00 48.79 ? 273 GLU A CA 1 ATOM 2227 C C . GLU A 1 274 ? -3.420 49.401 -66.741 1.00 43.36 ? 273 GLU A C 1 ATOM 2228 O O . GLU A 1 274 ? -3.294 49.604 -65.539 1.00 38.95 ? 273 GLU A O 1 ATOM 2229 C CB . GLU A 1 274 ? -2.026 48.882 -68.853 1.00 51.26 ? 273 GLU A CB 1 ATOM 2230 C CG . GLU A 1 274 ? -1.528 49.650 -70.113 1.00 55.14 ? 273 GLU A CG 1 ATOM 2231 C CD . GLU A 1 274 ? -0.789 48.777 -71.103 1.00 66.85 ? 273 GLU A CD 1 ATOM 2232 O OE1 . GLU A 1 274 ? 0.301 49.205 -71.572 1.00 51.52 ? 273 GLU A OE1 1 ATOM 2233 O OE2 . GLU A 1 274 ? -1.304 47.667 -71.407 1.00 68.01 ? 273 GLU A OE2 1 ATOM 2234 N N . TYR A 1 275 ? -4.518 48.849 -67.258 1.00 34.20 ? 274 TYR A N 1 ATOM 2235 C CA . TYR A 1 275 ? -5.681 48.671 -66.431 1.00 33.56 ? 274 TYR A CA 1 ATOM 2236 C C . TYR A 1 275 ? -5.450 47.761 -65.242 1.00 37.09 ? 274 TYR A C 1 ATOM 2237 O O . TYR A 1 275 ? -4.766 46.737 -65.353 1.00 38.19 ? 274 TYR A O 1 ATOM 2238 C CB . TYR A 1 275 ? -6.821 48.097 -67.247 1.00 38.90 ? 274 TYR A CB 1 ATOM 2239 C CG . TYR A 1 275 ? -8.173 48.109 -66.574 1.00 39.62 ? 274 TYR A CG 1 ATOM 2240 C CD1 . TYR A 1 275 ? -9.017 46.981 -66.641 1.00 35.22 ? 274 TYR A CD1 1 ATOM 2241 C CD2 . TYR A 1 275 ? -8.649 49.237 -65.917 1.00 33.70 ? 274 TYR A CD2 1 ATOM 2242 C CE1 . TYR A 1 275 ? -10.252 46.981 -66.087 1.00 36.59 ? 274 TYR A CE1 1 ATOM 2243 C CE2 . TYR A 1 275 ? -9.900 49.248 -65.346 1.00 28.84 ? 274 TYR A CE2 1 ATOM 2244 C CZ . TYR A 1 275 ? -10.713 48.090 -65.438 1.00 35.70 ? 274 TYR A CZ 1 ATOM 2245 O OH . TYR A 1 275 ? -11.972 48.062 -64.906 1.00 34.02 ? 274 TYR A OH 1 ATOM 2246 N N . GLY A 1 276 ? -6.044 48.114 -64.110 1.00 33.46 ? 275 GLY A N 1 ATOM 2247 C CA . GLY A 1 276 ? -5.810 47.369 -62.873 1.00 31.64 ? 275 GLY A CA 1 ATOM 2248 C C . GLY A 1 276 ? -6.991 46.550 -62.387 1.00 37.31 ? 275 GLY A C 1 ATOM 2249 O O . GLY A 1 276 ? -6.922 45.930 -61.320 1.00 37.41 ? 275 GLY A O 1 ATOM 2250 N N . ASN A 1 277 ? -8.090 46.572 -63.149 1.00 35.77 ? 276 ASN A N 1 ATOM 2251 C CA A ASN A 1 277 ? -9.301 45.849 -62.790 0.50 39.17 ? 276 ASN A CA 1 ATOM 2252 C CA B ASN A 1 277 ? -9.325 45.879 -62.776 0.50 39.16 ? 276 ASN A CA 1 ATOM 2253 C C . ASN A 1 277 ? -9.810 46.142 -61.365 1.00 48.05 ? 276 ASN A C 1 ATOM 2254 O O . ASN A 1 277 ? -10.092 45.212 -60.598 1.00 40.13 ? 276 ASN A O 1 ATOM 2255 C CB A ASN A 1 277 ? -9.064 44.345 -63.011 0.50 41.22 ? 276 ASN A CB 1 ATOM 2256 C CB B ASN A 1 277 ? -9.196 44.373 -62.977 0.50 41.22 ? 276 ASN A CB 1 ATOM 2257 C CG A ASN A 1 277 ? -8.605 44.030 -64.443 0.50 47.50 ? 276 ASN A CG 1 ATOM 2258 C CG B ASN A 1 277 ? -10.033 43.886 -64.121 0.50 50.23 ? 276 ASN A CG 1 ATOM 2259 O OD1 A ASN A 1 277 ? -7.404 43.945 -64.739 0.50 45.12 ? 276 ASN A OD1 1 ATOM 2260 O OD1 B ASN A 1 277 ? -9.508 43.586 -65.195 0.50 50.86 ? 276 ASN A OD1 1 ATOM 2261 N ND2 A ASN A 1 277 ? -9.571 43.885 -65.341 0.50 51.93 ? 276 ASN A ND2 1 ATOM 2262 N ND2 B ASN A 1 277 ? -11.351 43.835 -63.918 0.50 47.28 ? 276 ASN A ND2 1 ATOM 2263 N N . CYS A 1 278 ? -9.946 47.428 -61.028 1.00 38.58 ? 277 CYS A N 1 ATOM 2264 C CA . CYS A 1 278 ? -10.334 47.847 -59.689 1.00 39.20 ? 277 CYS A CA 1 ATOM 2265 C C . CYS A 1 278 ? -11.214 49.077 -59.790 1.00 39.74 ? 277 CYS A C 1 ATOM 2266 O O . CYS A 1 278 ? -11.445 49.602 -60.882 1.00 34.88 ? 277 CYS A O 1 ATOM 2267 C CB . CYS A 1 278 ? -9.061 48.190 -58.881 1.00 40.33 ? 277 CYS A CB 1 ATOM 2268 S SG . CYS A 1 278 ? -7.881 49.177 -59.890 1.00 45.94 ? 277 CYS A SG 1 ATOM 2269 N N . ASN A 1 279 ? -11.696 49.550 -58.656 1.00 34.92 ? 278 ASN A N 1 ATOM 2270 C CA . ASN A 1 279 ? -12.550 50.720 -58.637 1.00 32.02 ? 278 ASN A CA 1 ATOM 2271 C C . ASN A 1 279 ? -12.071 51.681 -57.542 1.00 37.61 ? 278 ASN A C 1 ATOM 2272 O O . ASN A 1 279 ? -11.556 51.233 -56.521 1.00 38.30 ? 278 ASN A O 1 ATOM 2273 C CB . ASN A 1 279 ? -13.998 50.304 -58.420 1.00 31.27 ? 278 ASN A CB 1 ATOM 2274 C CG . ASN A 1 279 ? -14.941 51.450 -58.495 1.00 34.31 ? 278 ASN A CG 1 ATOM 2275 O OD1 . ASN A 1 279 ? -14.768 52.366 -59.291 1.00 35.07 ? 278 ASN A OD1 1 ATOM 2276 N ND2 . ASN A 1 279 ? -15.973 51.421 -57.661 1.00 44.06 ? 278 ASN A ND2 1 ATOM 2277 N N . THR A 1 280 ? -12.214 52.988 -57.770 1.00 33.27 ? 279 THR A N 1 ATOM 2278 C CA . THR A 1 280 ? -11.730 53.994 -56.811 1.00 29.94 ? 279 THR A CA 1 ATOM 2279 C C . THR A 1 280 ? -12.556 55.261 -56.915 1.00 29.75 ? 279 THR A C 1 ATOM 2280 O O . THR A 1 280 ? -13.251 55.485 -57.933 1.00 28.65 ? 279 THR A O 1 ATOM 2281 C CB . THR A 1 280 ? -10.208 54.344 -57.080 1.00 25.78 ? 279 THR A CB 1 ATOM 2282 O OG1 . THR A 1 280 ? -9.678 55.081 -55.959 1.00 27.89 ? 279 THR A OG1 1 ATOM 2283 C CG2 . THR A 1 280 ? -10.030 55.249 -58.380 1.00 23.77 ? 279 THR A CG2 1 ATOM 2284 N N . LYS A 1 281 ? -12.442 56.137 -55.916 1.00 24.20 ? 280 LYS A N 1 ATOM 2285 C CA . LYS A 1 281 ? -13.031 57.465 -55.985 1.00 25.97 ? 280 LYS A CA 1 ATOM 2286 C C . LYS A 1 281 ? -11.983 58.545 -56.259 1.00 23.13 ? 280 LYS A C 1 ATOM 2287 O O . LYS A 1 281 ? -12.351 59.685 -56.554 1.00 26.20 ? 280 LYS A O 1 ATOM 2288 C CB . LYS A 1 281 ? -13.748 57.829 -54.687 1.00 34.25 ? 280 LYS A CB 1 ATOM 2289 C CG . LYS A 1 281 ? -14.964 56.936 -54.424 1.00 56.01 ? 280 LYS A CG 1 ATOM 2290 C CD . LYS A 1 281 ? -16.082 57.663 -53.660 1.00 76.65 ? 280 LYS A CD 1 ATOM 2291 C CE . LYS A 1 281 ? -17.382 56.849 -53.669 1.00 74.46 ? 280 LYS A CE 1 ATOM 2292 N NZ . LYS A 1 281 ? -18.494 57.546 -52.965 1.00 77.24 ? 280 LYS A NZ 1 ATOM 2293 N N . CYS A 1 282 ? -10.718 58.160 -56.199 1.00 23.11 ? 281 CYS A N 1 ATOM 2294 C CA . CYS A 1 282 ? -9.581 59.104 -56.416 1.00 26.51 ? 281 CYS A CA 1 ATOM 2295 C C . CYS A 1 282 ? -8.434 58.412 -57.145 1.00 27.04 ? 281 CYS A C 1 ATOM 2296 O O . CYS A 1 282 ? -7.852 57.450 -56.629 1.00 25.31 ? 281 CYS A O 1 ATOM 2297 C CB . CYS A 1 282 ? -9.110 59.646 -55.056 1.00 25.13 ? 281 CYS A CB 1 ATOM 2298 S SG . CYS A 1 282 ? -7.620 60.651 -55.213 1.00 25.04 ? 281 CYS A SG 1 ATOM 2299 N N . GLN A 1 283 ? -8.107 58.880 -58.364 1.00 21.90 ? 282 GLN A N 1 ATOM 2300 C CA . GLN A 1 283 ? -7.048 58.268 -59.143 1.00 25.22 ? 282 GLN A CA 1 ATOM 2301 C C . GLN A 1 283 ? -5.876 59.224 -59.391 1.00 21.82 ? 282 GLN A C 1 ATOM 2302 O O . GLN A 1 283 ? -6.088 60.427 -59.669 1.00 22.44 ? 282 GLN A O 1 ATOM 2303 C CB . GLN A 1 283 ? -7.630 57.860 -60.523 1.00 22.96 ? 282 GLN A CB 1 ATOM 2304 C CG . GLN A 1 283 ? -6.583 57.148 -61.371 1.00 25.09 ? 282 GLN A CG 1 ATOM 2305 C CD . GLN A 1 283 ? -6.302 55.720 -60.838 1.00 23.56 ? 282 GLN A CD 1 ATOM 2306 O OE1 . GLN A 1 283 ? -7.233 54.947 -60.600 1.00 25.40 ? 282 GLN A OE1 1 ATOM 2307 N NE2 . GLN A 1 283 ? -5.030 55.392 -60.664 1.00 21.74 ? 282 GLN A NE2 1 ATOM 2308 N N . THR A 1 284 ? -4.654 58.700 -59.322 1.00 20.72 ? 283 THR A N 1 ATOM 2309 C CA . THR A 1 284 ? -3.450 59.456 -59.689 1.00 19.69 ? 283 THR A CA 1 ATOM 2310 C C . THR A 1 284 ? -2.696 58.655 -60.735 1.00 24.62 ? 283 THR A C 1 ATOM 2311 O O . THR A 1 284 ? -2.978 57.465 -60.888 1.00 23.98 ? 283 THR A O 1 ATOM 2312 C CB . THR A 1 284 ? -2.473 59.644 -58.445 1.00 24.10 ? 283 THR A CB 1 ATOM 2313 O OG1 . THR A 1 284 ? -1.541 58.539 -58.372 1.00 23.30 ? 283 THR A OG1 1 ATOM 2314 C CG2 . THR A 1 284 ? -3.242 59.754 -57.123 1.00 25.17 ? 283 THR A CG2 1 ATOM 2315 N N . PRO A 1 285 ? -1.727 59.277 -61.429 1.00 22.83 ? 284 PRO A N 1 ATOM 2316 C CA . PRO A 1 285 ? -1.030 58.537 -62.492 1.00 23.34 ? 284 PRO A CA 1 ATOM 2317 C C . PRO A 1 285 ? -0.191 57.397 -61.934 1.00 27.75 ? 284 PRO A C 1 ATOM 2318 O O . PRO A 1 285 ? 0.258 56.583 -62.729 1.00 27.74 ? 284 PRO A O 1 ATOM 2319 C CB . PRO A 1 285 ? -0.076 59.571 -63.094 1.00 22.76 ? 284 PRO A CB 1 ATOM 2320 C CG . PRO A 1 285 ? -0.740 60.910 -62.801 1.00 26.12 ? 284 PRO A CG 1 ATOM 2321 C CD . PRO A 1 285 ? -1.368 60.711 -61.443 1.00 26.88 ? 284 PRO A CD 1 ATOM 2322 N N . MET A 1 286 ? 0.028 57.338 -60.620 1.00 26.88 ? 285 MET A N 1 ATOM 2323 C CA . MET A 1 286 ? 0.883 56.316 -60.041 1.00 26.95 ? 285 MET A CA 1 ATOM 2324 C C . MET A 1 286 ? 0.061 55.245 -59.424 1.00 27.32 ? 285 MET A C 1 ATOM 2325 O O . MET A 1 286 ? 0.597 54.222 -59.026 1.00 28.90 ? 285 MET A O 1 ATOM 2326 C CB . MET A 1 286 ? 1.723 56.967 -58.910 1.00 31.09 ? 285 MET A CB 1 ATOM 2327 C CG . MET A 1 286 ? 2.651 58.050 -59.455 1.00 35.49 ? 285 MET A CG 1 ATOM 2328 S SD . MET A 1 286 ? 3.596 58.822 -58.118 1.00 39.10 ? 285 MET A SD 1 ATOM 2329 C CE . MET A 1 286 ? 3.844 57.412 -57.053 1.00 37.56 ? 285 MET A CE 1 ATOM 2330 N N . GLY A 1 287 ? -1.233 55.462 -59.267 1.00 25.32 ? 286 GLY A N 1 ATOM 2331 C CA . GLY A 1 287 ? -2.032 54.561 -58.474 1.00 24.38 ? 286 GLY A CA 1 ATOM 2332 C C . GLY A 1 287 ? -3.242 55.220 -57.852 1.00 25.35 ? 286 GLY A C 1 ATOM 2333 O O . GLY A 1 287 ? -3.330 56.454 -57.762 1.00 24.46 ? 286 GLY A O 1 ATOM 2334 N N . ALA A 1 288 ? -4.197 54.444 -57.399 1.00 22.73 ? 287 ALA A N 1 ATOM 2335 C CA . ALA A 1 288 ? -5.417 54.991 -56.840 1.00 25.11 ? 287 ALA A CA 1 ATOM 2336 C C . ALA A 1 288 ? -5.315 55.164 -55.337 1.00 23.46 ? 287 ALA A C 1 ATOM 2337 O O . ALA A 1 288 ? -4.545 54.455 -54.709 1.00 26.13 ? 287 ALA A O 1 ATOM 2338 C CB . ALA A 1 288 ? -6.601 54.088 -57.126 1.00 28.37 ? 287 ALA A CB 1 ATOM 2339 N N . ILE A 1 289 ? -6.129 56.070 -54.809 1.00 22.83 ? 288 ILE A N 1 ATOM 2340 C CA . ILE A 1 289 ? -6.132 56.410 -53.370 1.00 20.00 ? 288 ILE A CA 1 ATOM 2341 C C . ILE A 1 289 ? -7.494 56.064 -52.759 1.00 20.67 ? 288 ILE A C 1 ATOM 2342 O O . ILE A 1 289 ? -8.549 56.427 -53.319 1.00 27.83 ? 288 ILE A O 1 ATOM 2343 C CB . ILE A 1 289 ? -5.795 57.933 -53.114 1.00 21.82 ? 288 ILE A CB 1 ATOM 2344 C CG1 . ILE A 1 289 ? -4.357 58.236 -53.514 1.00 20.39 ? 288 ILE A CG1 1 ATOM 2345 C CG2 . ILE A 1 289 ? -5.931 58.275 -51.646 1.00 25.55 ? 288 ILE A CG2 1 ATOM 2346 C CD1 . ILE A 1 289 ? -4.049 59.824 -53.569 1.00 25.46 ? 288 ILE A CD1 1 ATOM 2347 N N A ASN A 1 290 ? -7.464 55.364 -51.615 0.65 27.27 ? 289 ASN A N 1 ATOM 2348 N N B ASN A 1 290 ? -7.498 55.372 -51.624 0.35 27.28 ? 289 ASN A N 1 ATOM 2349 C CA A ASN A 1 290 ? -8.660 55.075 -50.828 0.65 26.52 ? 289 ASN A CA 1 ATOM 2350 C CA B ASN A 1 290 ? -8.743 55.184 -50.896 0.35 26.52 ? 289 ASN A CA 1 ATOM 2351 C C A ASN A 1 290 ? -8.407 55.605 -49.431 0.65 26.88 ? 289 ASN A C 1 ATOM 2352 C C B ASN A 1 290 ? -8.531 55.569 -49.439 0.35 26.93 ? 289 ASN A C 1 ATOM 2353 O O A ASN A 1 290 ? -7.732 54.949 -48.663 0.65 29.22 ? 289 ASN A O 1 ATOM 2354 O O B ASN A 1 290 ? -8.025 54.797 -48.645 0.35 29.19 ? 289 ASN A O 1 ATOM 2355 C CB A ASN A 1 290 ? -8.909 53.549 -50.749 0.65 28.01 ? 289 ASN A CB 1 ATOM 2356 C CB B ASN A 1 290 ? -9.274 53.753 -51.049 0.35 30.06 ? 289 ASN A CB 1 ATOM 2357 C CG A ASN A 1 290 ? -10.227 53.184 -49.993 0.65 30.72 ? 289 ASN A CG 1 ATOM 2358 C CG B ASN A 1 290 ? -8.275 52.718 -50.633 0.35 25.88 ? 289 ASN A CG 1 ATOM 2359 O OD1 A ASN A 1 290 ? -10.772 53.968 -49.216 0.65 33.48 ? 289 ASN A OD1 1 ATOM 2360 O OD1 B ASN A 1 290 ? -7.075 52.851 -50.887 0.35 33.23 ? 289 ASN A OD1 1 ATOM 2361 N ND2 A ASN A 1 290 ? -10.722 51.972 -50.235 0.65 42.46 ? 289 ASN A ND2 1 ATOM 2362 N ND2 B ASN A 1 290 ? -8.760 51.670 -49.962 0.35 33.30 ? 289 ASN A ND2 1 ATOM 2363 N N . SER A 1 291 ? -8.889 56.800 -49.124 1.00 25.17 ? 290 SER A N 1 ATOM 2364 C CA . SER A 1 291 ? -8.483 57.426 -47.867 1.00 26.45 ? 290 SER A CA 1 ATOM 2365 C C . SER A 1 291 ? -9.419 58.528 -47.482 1.00 31.80 ? 290 SER A C 1 ATOM 2366 O O . SER A 1 291 ? -9.997 59.213 -48.346 1.00 30.69 ? 290 SER A O 1 ATOM 2367 C CB . SER A 1 291 ? -7.087 58.041 -48.064 1.00 25.21 ? 290 SER A CB 1 ATOM 2368 O OG . SER A 1 291 ? -6.636 58.672 -46.858 1.00 29.39 ? 290 SER A OG 1 ATOM 2369 N N . SER A 1 292 ? -9.553 58.745 -46.167 1.00 26.41 ? 291 SER A N 1 ATOM 2370 C CA . SER A 1 292 ? -10.287 59.907 -45.712 1.00 24.38 ? 291 SER A CA 1 ATOM 2371 C C . SER A 1 292 ? -9.327 61.014 -45.164 1.00 22.22 ? 291 SER A C 1 ATOM 2372 O O . SER A 1 292 ? -9.811 62.049 -44.694 1.00 25.55 ? 291 SER A O 1 ATOM 2373 C CB . SER A 1 292 ? -11.256 59.458 -44.584 1.00 32.92 ? 291 SER A CB 1 ATOM 2374 O OG . SER A 1 292 ? -10.422 58.955 -43.508 1.00 35.28 ? 291 SER A OG 1 ATOM 2375 N N . MET A 1 293 ? -8.013 60.799 -45.249 1.00 23.53 ? 292 MET A N 1 ATOM 2376 C CA . MET A 1 293 ? -7.067 61.861 -44.820 1.00 23.73 ? 292 MET A CA 1 ATOM 2377 C C . MET A 1 293 ? -7.333 63.158 -45.596 1.00 27.09 ? 292 MET A C 1 ATOM 2378 O O . MET A 1 293 ? -7.710 63.142 -46.750 1.00 24.45 ? 292 MET A O 1 ATOM 2379 C CB . MET A 1 293 ? -5.643 61.429 -45.049 1.00 23.08 ? 292 MET A CB 1 ATOM 2380 C CG . MET A 1 293 ? -5.153 60.122 -44.361 1.00 30.30 ? 292 MET A CG 1 ATOM 2381 S SD . MET A 1 293 ? -5.051 60.489 -42.585 1.00 32.78 ? 292 MET A SD 1 ATOM 2382 C CE . MET A 1 293 ? -3.877 59.267 -41.961 1.00 33.91 ? 292 MET A CE 1 ATOM 2383 N N . PRO A 1 294 ? -7.154 64.302 -44.940 1.00 25.57 ? 293 PRO A N 1 ATOM 2384 C CA . PRO A 1 294 ? -7.359 65.572 -45.625 1.00 26.05 ? 293 PRO A CA 1 ATOM 2385 C C . PRO A 1 294 ? -6.249 65.837 -46.643 1.00 24.99 ? 293 PRO A C 1 ATOM 2386 O O . PRO A 1 294 ? -6.467 66.640 -47.546 1.00 23.56 ? 293 PRO A O 1 ATOM 2387 C CB . PRO A 1 294 ? -7.266 66.615 -44.498 1.00 28.90 ? 293 PRO A CB 1 ATOM 2388 C CG . PRO A 1 294 ? -6.471 65.889 -43.357 1.00 24.92 ? 293 PRO A CG 1 ATOM 2389 C CD . PRO A 1 294 ? -6.928 64.423 -43.473 1.00 20.00 ? 293 PRO A CD 1 ATOM 2390 N N . PHE A 1 295 ? -5.067 65.245 -46.453 1.00 19.72 ? 294 PHE A N 1 ATOM 2391 C CA . PHE A 1 295 ? -3.911 65.518 -47.349 1.00 21.30 ? 294 PHE A CA 1 ATOM 2392 C C . PHE A 1 295 ? -3.309 64.212 -47.898 1.00 21.42 ? 294 PHE A C 1 ATOM 2393 O O . PHE A 1 295 ? -3.432 63.173 -47.279 1.00 20.25 ? 294 PHE A O 1 ATOM 2394 C CB . PHE A 1 295 ? -2.778 66.185 -46.574 1.00 20.50 ? 294 PHE A CB 1 ATOM 2395 C CG . PHE A 1 295 ? -3.114 67.576 -46.055 1.00 21.70 ? 294 PHE A CG 1 ATOM 2396 C CD1 . PHE A 1 295 ? -3.125 68.628 -46.932 1.00 22.11 ? 294 PHE A CD1 1 ATOM 2397 C CD2 . PHE A 1 295 ? -3.431 67.784 -44.723 1.00 23.42 ? 294 PHE A CD2 1 ATOM 2398 C CE1 . PHE A 1 295 ? -3.449 69.925 -46.497 1.00 26.97 ? 294 PHE A CE1 1 ATOM 2399 C CE2 . PHE A 1 295 ? -3.778 69.049 -44.269 1.00 26.59 ? 294 PHE A CE2 1 ATOM 2400 C CZ . PHE A 1 295 ? -3.778 70.121 -45.131 1.00 24.53 ? 294 PHE A CZ 1 ATOM 2401 N N . HIS A 1 296 ? -2.585 64.287 -49.029 1.00 19.36 ? 295 HIS A N 1 ATOM 2402 C CA . HIS A 1 296 ? -1.821 63.136 -49.478 1.00 17.18 ? 295 HIS A CA 1 ATOM 2403 C C . HIS A 1 296 ? -0.569 63.616 -50.147 1.00 18.29 ? 295 HIS A C 1 ATOM 2404 O O . HIS A 1 296 ? -0.479 64.790 -50.478 1.00 21.42 ? 295 HIS A O 1 ATOM 2405 C CB . HIS A 1 296 ? -2.684 62.285 -50.465 1.00 18.53 ? 295 HIS A CB 1 ATOM 2406 C CG . HIS A 1 296 ? -2.802 62.866 -51.829 1.00 18.75 ? 295 HIS A CG 1 ATOM 2407 N ND1 . HIS A 1 296 ? -1.928 62.561 -52.863 1.00 21.53 ? 295 HIS A ND1 1 ATOM 2408 C CD2 . HIS A 1 296 ? -3.688 63.762 -52.328 1.00 19.99 ? 295 HIS A CD2 1 ATOM 2409 C CE1 . HIS A 1 296 ? -2.304 63.216 -53.954 1.00 21.71 ? 295 HIS A CE1 1 ATOM 2410 N NE2 . HIS A 1 296 ? -3.362 63.970 -53.653 1.00 20.59 ? 295 HIS A NE2 1 ATOM 2411 N N . ASN A 1 297 ? 0.448 62.766 -50.312 1.00 19.14 ? 296 ASN A N 1 ATOM 2412 C CA . ASN A 1 297 ? 1.643 63.197 -51.013 1.00 18.56 ? 296 ASN A CA 1 ATOM 2413 C C . ASN A 1 297 ? 2.022 62.329 -52.247 1.00 17.93 ? 296 ASN A C 1 ATOM 2414 O O . ASN A 1 297 ? 3.215 62.187 -52.549 1.00 21.66 ? 296 ASN A O 1 ATOM 2415 C CB . ASN A 1 297 ? 2.850 63.274 -50.069 1.00 18.43 ? 296 ASN A CB 1 ATOM 2416 C CG . ASN A 1 297 ? 3.263 61.918 -49.540 1.00 25.11 ? 296 ASN A CG 1 ATOM 2417 O OD1 . ASN A 1 297 ? 2.662 60.901 -49.892 1.00 25.16 ? 296 ASN A OD1 1 ATOM 2418 N ND2 . ASN A 1 297 ? 4.313 61.889 -48.731 1.00 23.16 ? 296 ASN A ND2 1 ATOM 2419 N N . ILE A 1 298 ? 1.022 61.742 -52.879 1.00 19.67 ? 297 ILE A N 1 ATOM 2420 C CA . ILE A 1 298 ? 1.309 60.711 -53.896 1.00 20.86 ? 297 ILE A CA 1 ATOM 2421 C C . ILE A 1 298 ? 1.744 61.373 -55.222 1.00 23.18 ? 297 ILE A C 1 ATOM 2422 O O . ILE A 1 298 ? 2.878 61.125 -55.710 1.00 24.03 ? 297 ILE A O 1 ATOM 2423 C CB . ILE A 1 298 ? 0.065 59.807 -54.163 1.00 20.65 ? 297 ILE A CB 1 ATOM 2424 C CG1 . ILE A 1 298 ? -0.554 59.211 -52.889 1.00 26.16 ? 297 ILE A CG1 1 ATOM 2425 C CG2 . ILE A 1 298 ? 0.453 58.714 -55.238 1.00 25.56 ? 297 ILE A CG2 1 ATOM 2426 C CD1 . ILE A 1 298 ? 0.415 58.569 -51.961 1.00 25.80 ? 297 ILE A CD1 1 ATOM 2427 N N . HIS A 1 299 ? 0.909 62.261 -55.770 1.00 22.37 ? 298 HIS A N 1 ATOM 2428 C CA . HIS A 1 299 ? 1.215 62.933 -57.068 1.00 25.68 ? 298 HIS A CA 1 ATOM 2429 C C . HIS A 1 299 ? 0.220 64.080 -57.187 1.00 19.38 ? 298 HIS A C 1 ATOM 2430 O O . HIS A 1 299 ? -0.910 63.956 -56.761 1.00 20.59 ? 298 HIS A O 1 ATOM 2431 C CB . HIS A 1 299 ? 0.962 61.919 -58.216 1.00 25.05 ? 298 HIS A CB 1 ATOM 2432 C CG . HIS A 1 299 ? 1.448 62.376 -59.561 1.00 22.77 ? 298 HIS A CG 1 ATOM 2433 N ND1 . HIS A 1 299 ? 0.833 63.373 -60.298 1.00 22.55 ? 298 HIS A ND1 1 ATOM 2434 C CD2 . HIS A 1 299 ? 2.473 61.913 -60.338 1.00 25.94 ? 298 HIS A CD2 1 ATOM 2435 C CE1 . HIS A 1 299 ? 1.486 63.537 -61.440 1.00 26.55 ? 298 HIS A CE1 1 ATOM 2436 N NE2 . HIS A 1 299 ? 2.488 62.667 -61.489 1.00 27.13 ? 298 HIS A NE2 1 ATOM 2437 N N . PRO A 1 300 ? 0.627 65.200 -57.765 1.00 21.56 ? 299 PRO A N 1 ATOM 2438 C CA . PRO A 1 300 ? -0.276 66.367 -57.815 1.00 25.85 ? 299 PRO A CA 1 ATOM 2439 C C . PRO A 1 300 ? -1.448 66.216 -58.780 1.00 22.98 ? 299 PRO A C 1 ATOM 2440 O O . PRO A 1 300 ? -2.482 66.915 -58.690 1.00 22.94 ? 299 PRO A O 1 ATOM 2441 C CB . PRO A 1 300 ? 0.645 67.516 -58.252 1.00 27.62 ? 299 PRO A CB 1 ATOM 2442 C CG . PRO A 1 300 ? 1.830 66.825 -58.910 1.00 27.73 ? 299 PRO A CG 1 ATOM 2443 C CD . PRO A 1 300 ? 2.012 65.532 -58.153 1.00 23.37 ? 299 PRO A CD 1 ATOM 2444 N N . LEU A 1 301 ? -1.279 65.363 -59.792 1.00 19.93 ? 300 LEU A N 1 ATOM 2445 C CA . LEU A 1 301 ? -2.268 65.404 -60.857 1.00 20.96 ? 300 LEU A CA 1 ATOM 2446 C C . LEU A 1 301 ? -3.329 64.337 -60.689 1.00 31.69 ? 300 LEU A C 1 ATOM 2447 O O . LEU A 1 301 ? -3.247 63.280 -61.311 1.00 34.01 ? 300 LEU A O 1 ATOM 2448 C CB . LEU A 1 301 ? -1.635 65.243 -62.247 1.00 21.19 ? 300 LEU A CB 1 ATOM 2449 C CG . LEU A 1 301 ? -0.799 66.430 -62.652 1.00 31.05 ? 300 LEU A CG 1 ATOM 2450 C CD1 . LEU A 1 301 ? -0.089 66.134 -64.015 1.00 26.74 ? 300 LEU A CD1 1 ATOM 2451 C CD2 . LEU A 1 301 ? -1.647 67.726 -62.739 1.00 30.57 ? 300 LEU A CD2 1 ATOM 2452 N N . THR A 1 302 ? -4.354 64.635 -59.920 1.00 20.90 ? 301 THR A N 1 ATOM 2453 C CA . THR A 1 302 ? -5.334 63.592 -59.599 1.00 22.56 ? 301 THR A CA 1 ATOM 2454 C C . THR A 1 302 ? -6.684 63.879 -60.231 1.00 27.01 ? 301 THR A C 1 ATOM 2455 O O . THR A 1 302 ? -6.932 64.994 -60.740 1.00 27.12 ? 301 THR A O 1 ATOM 2456 C CB . THR A 1 302 ? -5.490 63.456 -58.052 1.00 27.28 ? 301 THR A CB 1 ATOM 2457 O OG1 . THR A 1 302 ? -6.127 64.616 -57.513 1.00 25.36 ? 301 THR A OG1 1 ATOM 2458 C CG2 . THR A 1 302 ? -4.117 63.353 -57.388 1.00 23.08 ? 301 THR A CG2 1 ATOM 2459 N N . ILE A 1 303 ? -7.554 62.879 -60.212 1.00 20.69 ? 302 ILE A N 1 ATOM 2460 C CA . ILE A 1 303 ? -8.959 63.121 -60.584 1.00 21.36 ? 302 ILE A CA 1 ATOM 2461 C C . ILE A 1 303 ? -9.853 62.382 -59.605 1.00 24.51 ? 302 ILE A C 1 ATOM 2462 O O . ILE A 1 303 ? -9.498 61.306 -59.129 1.00 24.47 ? 302 ILE A O 1 ATOM 2463 C CB . ILE A 1 303 ? -9.236 62.664 -62.077 1.00 24.18 ? 302 ILE A CB 1 ATOM 2464 C CG1 . ILE A 1 303 ? -10.636 63.072 -62.520 1.00 25.74 ? 302 ILE A CG1 1 ATOM 2465 C CG2 . ILE A 1 303 ? -8.949 61.193 -62.259 1.00 30.58 ? 302 ILE A CG2 1 ATOM 2466 C CD1 . ILE A 1 303 ? -10.962 62.771 -64.019 1.00 31.60 ? 302 ILE A CD1 1 ATOM 2467 N N . GLY A 1 304 ? -10.995 62.975 -59.292 1.00 23.33 ? 303 GLY A N 1 ATOM 2468 C CA . GLY A 1 304 ? -11.954 62.305 -58.429 1.00 27.12 ? 303 GLY A CA 1 ATOM 2469 C C . GLY A 1 304 ? -12.095 63.103 -57.156 1.00 26.81 ? 303 GLY A C 1 ATOM 2470 O O . GLY A 1 304 ? -11.788 64.320 -57.135 1.00 32.26 ? 303 GLY A O 1 ATOM 2471 N N A GLU A 1 305 ? -12.569 62.452 -56.107 0.45 25.64 ? 304 GLU A N 1 ATOM 2472 N N B GLU A 1 305 ? -12.535 62.425 -56.107 0.55 25.59 ? 304 GLU A N 1 ATOM 2473 C CA A GLU A 1 305 ? -12.727 63.102 -54.813 0.45 30.26 ? 304 GLU A CA 1 ATOM 2474 C CA B GLU A 1 305 ? -12.719 63.024 -54.790 0.55 30.30 ? 304 GLU A CA 1 ATOM 2475 C C A GLU A 1 305 ? -11.500 62.725 -53.994 0.45 25.50 ? 304 GLU A C 1 ATOM 2476 C C B GLU A 1 305 ? -11.471 62.694 -53.992 0.55 25.46 ? 304 GLU A C 1 ATOM 2477 O O A GLU A 1 305 ? -11.431 61.649 -53.407 0.45 27.60 ? 304 GLU A O 1 ATOM 2478 O O B GLU A 1 305 ? -11.355 61.615 -53.414 0.55 27.60 ? 304 GLU A O 1 ATOM 2479 C CB A GLU A 1 305 ? -14.000 62.608 -54.121 0.45 33.44 ? 304 GLU A CB 1 ATOM 2480 C CB B GLU A 1 305 ? -13.934 62.395 -54.099 0.55 33.45 ? 304 GLU A CB 1 ATOM 2481 C CG A GLU A 1 305 ? -15.279 62.763 -54.954 0.45 31.90 ? 304 GLU A CG 1 ATOM 2482 C CG B GLU A 1 305 ? -14.388 63.114 -52.829 0.55 27.83 ? 304 GLU A CG 1 ATOM 2483 C CD A GLU A 1 305 ? -16.424 61.876 -54.438 0.45 39.62 ? 304 GLU A CD 1 ATOM 2484 C CD B GLU A 1 305 ? -15.652 62.480 -52.219 0.55 38.83 ? 304 GLU A CD 1 ATOM 2485 O OE1 A GLU A 1 305 ? -16.956 62.176 -53.345 0.45 41.17 ? 304 GLU A OE1 1 ATOM 2486 O OE1 B GLU A 1 305 ? -16.607 63.224 -51.886 0.55 47.78 ? 304 GLU A OE1 1 ATOM 2487 O OE2 A GLU A 1 305 ? -16.763 60.870 -55.108 0.45 33.33 ? 304 GLU A OE2 1 ATOM 2488 O OE2 B GLU A 1 305 ? -15.693 61.239 -52.071 0.55 49.81 ? 304 GLU A OE2 1 ATOM 2489 N N . CYS A 1 306 ? -10.523 63.620 -53.985 1.00 23.78 ? 305 CYS A N 1 ATOM 2490 C CA . CYS A 1 306 ? -9.237 63.315 -53.476 1.00 23.73 ? 305 CYS A CA 1 ATOM 2491 C C . CYS A 1 306 ? -8.894 64.159 -52.254 1.00 21.05 ? 305 CYS A C 1 ATOM 2492 O O . CYS A 1 306 ? -9.418 65.292 -52.121 1.00 25.56 ? 305 CYS A O 1 ATOM 2493 C CB . CYS A 1 306 ? -8.178 63.618 -54.540 1.00 25.21 ? 305 CYS A CB 1 ATOM 2494 S SG . CYS A 1 306 ? -8.360 62.480 -55.989 1.00 31.42 ? 305 CYS A SG 1 ATOM 2495 N N . PRO A 1 307 ? -7.921 63.693 -51.454 1.00 24.17 ? 306 PRO A N 1 ATOM 2496 C CA . PRO A 1 307 ? -7.309 64.587 -50.447 1.00 21.02 ? 306 PRO A CA 1 ATOM 2497 C C . PRO A 1 307 ? -6.554 65.718 -51.159 1.00 24.76 ? 306 PRO A C 1 ATOM 2498 O O . PRO A 1 307 ? -6.380 65.688 -52.372 1.00 24.04 ? 306 PRO A O 1 ATOM 2499 C CB . PRO A 1 307 ? -6.263 63.715 -49.723 1.00 21.03 ? 306 PRO A CB 1 ATOM 2500 C CG . PRO A 1 307 ? -6.749 62.266 -50.013 1.00 23.48 ? 306 PRO A CG 1 ATOM 2501 C CD . PRO A 1 307 ? -7.309 62.352 -51.445 1.00 26.47 ? 306 PRO A CD 1 ATOM 2502 N N . LYS A 1 308 ? -6.091 66.700 -50.403 1.00 25.07 ? 307 LYS A N 1 ATOM 2503 C CA . LYS A 1 308 ? -5.295 67.751 -51.039 1.00 26.49 ? 307 LYS A CA 1 ATOM 2504 C C . LYS A 1 308 ? -3.816 67.387 -51.120 1.00 23.28 ? 307 LYS A C 1 ATOM 2505 O O . LYS A 1 308 ? -3.233 66.867 -50.153 1.00 22.17 ? 307 LYS A O 1 ATOM 2506 C CB . LYS A 1 308 ? -5.500 69.065 -50.266 1.00 30.96 ? 307 LYS A CB 1 ATOM 2507 C CG . LYS A 1 308 ? -7.003 69.486 -50.232 1.00 39.43 ? 307 LYS A CG 1 ATOM 2508 C CD . LYS A 1 308 ? -7.500 70.001 -51.643 1.00 47.38 ? 307 LYS A CD 1 ATOM 2509 C CE . LYS A 1 308 ? -8.994 70.330 -51.702 1.00 55.77 ? 307 LYS A CE 1 ATOM 2510 N NZ . LYS A 1 308 ? -9.325 71.220 -52.856 1.00 66.33 ? 307 LYS A NZ 1 ATOM 2511 N N . TYR A 1 309 ? -3.208 67.595 -52.284 1.00 21.58 ? 308 TYR A N 1 ATOM 2512 C CA . TYR A 1 309 ? -1.808 67.211 -52.437 1.00 21.31 ? 308 TYR A CA 1 ATOM 2513 C C . TYR A 1 309 ? -0.859 68.221 -51.779 1.00 21.49 ? 308 TYR A C 1 ATOM 2514 O O . TYR A 1 309 ? -1.051 69.430 -51.936 1.00 22.51 ? 308 TYR A O 1 ATOM 2515 C CB . TYR A 1 309 ? -1.431 67.181 -53.918 1.00 20.69 ? 308 TYR A CB 1 ATOM 2516 C CG . TYR A 1 309 ? -0.011 66.842 -54.124 1.00 20.64 ? 308 TYR A CG 1 ATOM 2517 C CD1 . TYR A 1 309 ? 0.466 65.566 -53.934 1.00 19.48 ? 308 TYR A CD1 1 ATOM 2518 C CD2 . TYR A 1 309 ? 0.897 67.827 -54.471 1.00 28.61 ? 308 TYR A CD2 1 ATOM 2519 C CE1 . TYR A 1 309 ? 1.788 65.276 -54.114 1.00 22.22 ? 308 TYR A CE1 1 ATOM 2520 C CE2 . TYR A 1 309 ? 2.186 67.548 -54.648 1.00 29.44 ? 308 TYR A CE2 1 ATOM 2521 C CZ . TYR A 1 309 ? 2.663 66.273 -54.528 1.00 26.58 ? 308 TYR A CZ 1 ATOM 2522 O OH . TYR A 1 309 ? 4.013 66.043 -54.711 1.00 26.25 ? 308 TYR A OH 1 ATOM 2523 N N . VAL A 1 310 ? 0.105 67.717 -51.016 1.00 19.83 ? 309 VAL A N 1 ATOM 2524 C CA . VAL A 1 310 ? 1.253 68.500 -50.523 1.00 18.62 ? 309 VAL A CA 1 ATOM 2525 C C . VAL A 1 310 ? 2.538 67.747 -50.695 1.00 20.81 ? 309 VAL A C 1 ATOM 2526 O O . VAL A 1 310 ? 2.518 66.518 -50.842 1.00 21.83 ? 309 VAL A O 1 ATOM 2527 C CB . VAL A 1 310 ? 1.131 68.815 -49.019 1.00 21.73 ? 309 VAL A CB 1 ATOM 2528 C CG1 . VAL A 1 310 ? -0.025 69.746 -48.822 1.00 23.61 ? 309 VAL A CG1 1 ATOM 2529 C CG2 . VAL A 1 310 ? 0.954 67.494 -48.216 1.00 21.65 ? 309 VAL A CG2 1 ATOM 2530 N N . LYS A 1 311 ? 3.663 68.469 -50.759 1.00 21.79 ? 310 LYS A N 1 ATOM 2531 C CA . LYS A 1 311 ? 4.973 67.809 -50.900 1.00 24.84 ? 310 LYS A CA 1 ATOM 2532 C C . LYS A 1 311 ? 5.526 67.149 -49.622 1.00 28.33 ? 310 LYS A C 1 ATOM 2533 O O . LYS A 1 311 ? 6.532 66.453 -49.662 1.00 30.47 ? 310 LYS A O 1 ATOM 2534 C CB . LYS A 1 311 ? 6.032 68.763 -51.500 1.00 29.14 ? 310 LYS A CB 1 ATOM 2535 C CG . LYS A 1 311 ? 5.700 69.295 -52.851 1.00 35.16 ? 310 LYS A CG 1 ATOM 2536 C CD . LYS A 1 311 ? 6.858 70.234 -53.319 1.00 40.24 ? 310 LYS A CD 1 ATOM 2537 C CE . LYS A 1 311 ? 6.669 70.709 -54.758 1.00 48.59 ? 310 LYS A CE 1 ATOM 2538 N NZ . LYS A 1 311 ? 7.655 71.719 -55.236 1.00 42.35 ? 310 LYS A NZ 1 ATOM 2539 N N . SER A 1 312 ? 4.824 67.286 -48.513 1.00 22.73 ? 311 SER A N 1 ATOM 2540 C CA . SER A 1 312 ? 5.347 66.873 -47.226 1.00 21.37 ? 311 SER A CA 1 ATOM 2541 C C . SER A 1 312 ? 5.564 65.374 -47.097 1.00 23.85 ? 311 SER A C 1 ATOM 2542 O O . SER A 1 312 ? 4.835 64.617 -47.695 1.00 25.77 ? 311 SER A O 1 ATOM 2543 C CB . SER A 1 312 ? 4.276 67.205 -46.160 1.00 25.74 ? 311 SER A CB 1 ATOM 2544 O OG . SER A 1 312 ? 3.836 68.564 -46.274 1.00 26.53 ? 311 SER A OG 1 ATOM 2545 N N . ASN A 1 313 ? 6.551 64.954 -46.321 1.00 21.36 ? 312 ASN A N 1 ATOM 2546 C CA A ASN A 1 313 ? 6.711 63.548 -46.015 0.50 24.44 ? 312 ASN A CA 1 ATOM 2547 C CA B ASN A 1 313 ? 6.692 63.532 -46.018 0.50 24.45 ? 312 ASN A CA 1 ATOM 2548 C C . ASN A 1 313 ? 6.026 63.145 -44.709 1.00 24.64 ? 312 ASN A C 1 ATOM 2549 O O . ASN A 1 313 ? 5.888 61.939 -44.428 1.00 26.05 ? 312 ASN A O 1 ATOM 2550 C CB A ASN A 1 313 ? 8.188 63.187 -46.022 0.50 29.26 ? 312 ASN A CB 1 ATOM 2551 C CB B ASN A 1 313 ? 8.147 63.071 -46.007 0.50 29.42 ? 312 ASN A CB 1 ATOM 2552 C CG A ASN A 1 313 ? 8.717 63.018 -47.446 0.50 27.80 ? 312 ASN A CG 1 ATOM 2553 C CG B ASN A 1 313 ? 9.048 63.987 -45.243 0.50 35.98 ? 312 ASN A CG 1 ATOM 2554 O OD1 A ASN A 1 313 ? 8.050 62.405 -48.285 0.50 37.25 ? 312 ASN A OD1 1 ATOM 2555 O OD1 B ASN A 1 313 ? 8.652 64.573 -44.230 0.50 40.22 ? 312 ASN A OD1 1 ATOM 2556 N ND2 A ASN A 1 313 ? 9.878 63.580 -47.731 0.50 38.85 ? 312 ASN A ND2 1 ATOM 2557 N ND2 B ASN A 1 313 ? 10.293 64.132 -45.727 0.50 40.12 ? 312 ASN A ND2 1 ATOM 2558 N N . ARG A 1 314 ? 5.585 64.140 -43.913 1.00 23.29 ? 313 ARG A N 1 ATOM 2559 C CA . ARG A 1 314 ? 4.984 63.852 -42.589 1.00 23.15 ? 313 ARG A CA 1 ATOM 2560 C C . ARG A 1 314 ? 4.136 65.033 -42.134 1.00 23.11 ? 313 ARG A C 1 ATOM 2561 O O . ARG A 1 314 ? 4.573 66.180 -42.235 1.00 22.43 ? 313 ARG A O 1 ATOM 2562 C CB . ARG A 1 314 ? 6.096 63.577 -41.550 1.00 22.75 ? 313 ARG A CB 1 ATOM 2563 C CG . ARG A 1 314 ? 5.546 63.145 -40.219 1.00 26.58 ? 313 ARG A CG 1 ATOM 2564 C CD . ARG A 1 314 ? 6.515 62.190 -39.486 1.00 32.32 ? 313 ARG A CD 1 ATOM 2565 N NE . ARG A 1 314 ? 5.838 61.542 -38.320 1.00 32.79 ? 313 ARG A NE 1 ATOM 2566 C CZ . ARG A 1 314 ? 5.892 62.071 -37.109 1.00 27.72 ? 313 ARG A CZ 1 ATOM 2567 N NH1 . ARG A 1 314 ? 6.618 63.158 -36.931 1.00 35.26 ? 313 ARG A NH1 1 ATOM 2568 N NH2 . ARG A 1 314 ? 5.323 61.467 -36.071 1.00 37.71 ? 313 ARG A NH2 1 ATOM 2569 N N . LEU A 1 315 ? 2.892 64.758 -41.763 1.00 20.07 ? 314 LEU A N 1 ATOM 2570 C CA . LEU A 1 315 ? 2.076 65.793 -41.125 1.00 19.72 ? 314 LEU A CA 1 ATOM 2571 C C . LEU A 1 315 ? 1.320 65.094 -39.992 1.00 21.16 ? 314 LEU A C 1 ATOM 2572 O O . LEU A 1 315 ? 0.474 64.245 -40.255 1.00 22.08 ? 314 LEU A O 1 ATOM 2573 C CB . LEU A 1 315 ? 1.043 66.351 -42.094 1.00 21.22 ? 314 LEU A CB 1 ATOM 2574 C CG . LEU A 1 315 ? 1.479 67.259 -43.227 1.00 21.53 ? 314 LEU A CG 1 ATOM 2575 C CD1 . LEU A 1 315 ? 0.285 67.556 -44.185 1.00 21.11 ? 314 LEU A CD1 1 ATOM 2576 C CD2 . LEU A 1 315 ? 2.101 68.621 -42.652 1.00 22.41 ? 314 LEU A CD2 1 ATOM 2577 N N . VAL A 1 316 ? 1.608 65.434 -38.727 1.00 17.45 ? 315 VAL A N 1 ATOM 2578 C CA . VAL A 1 316 ? 0.931 64.784 -37.629 1.00 16.69 ? 315 VAL A CA 1 ATOM 2579 C C . VAL A 1 316 ? 0.490 65.847 -36.635 1.00 18.67 ? 315 VAL A C 1 ATOM 2580 O O . VAL A 1 316 ? 1.333 66.660 -36.227 1.00 18.84 ? 315 VAL A O 1 ATOM 2581 C CB . VAL A 1 316 ? 1.874 63.818 -36.923 1.00 19.73 ? 315 VAL A CB 1 ATOM 2582 C CG1 . VAL A 1 316 ? 1.100 63.119 -35.736 1.00 18.26 ? 315 VAL A CG1 1 ATOM 2583 C CG2 . VAL A 1 316 ? 2.353 62.746 -37.957 1.00 22.33 ? 315 VAL A CG2 1 ATOM 2584 N N . LEU A 1 317 ? -0.805 65.871 -36.309 1.00 17.18 ? 316 LEU A N 1 ATOM 2585 C CA . LEU A 1 317 ? -1.319 66.843 -35.326 1.00 15.87 ? 316 LEU A CA 1 ATOM 2586 C C . LEU A 1 317 ? -1.288 66.252 -33.950 1.00 23.43 ? 316 LEU A C 1 ATOM 2587 O O . LEU A 1 317 ? -1.740 65.125 -33.731 1.00 21.52 ? 316 LEU A O 1 ATOM 2588 C CB . LEU A 1 317 ? -2.778 67.148 -35.626 1.00 19.68 ? 316 LEU A CB 1 ATOM 2589 C CG . LEU A 1 317 ? -2.926 68.214 -36.696 1.00 22.76 ? 316 LEU A CG 1 ATOM 2590 C CD1 . LEU A 1 317 ? -4.390 68.215 -37.153 1.00 25.27 ? 316 LEU A CD1 1 ATOM 2591 C CD2 . LEU A 1 317 ? -2.547 69.592 -36.136 1.00 19.70 ? 316 LEU A CD2 1 ATOM 2592 N N . ALA A 1 318 ? -0.817 67.035 -32.990 1.00 19.45 ? 317 ALA A N 1 ATOM 2593 C CA . ALA A 1 318 ? -0.970 66.647 -31.602 1.00 19.19 ? 317 ALA A CA 1 ATOM 2594 C C . ALA A 1 318 ? -2.446 66.676 -31.187 1.00 19.44 ? 317 ALA A C 1 ATOM 2595 O O . ALA A 1 318 ? -3.180 67.618 -31.529 1.00 20.98 ? 317 ALA A O 1 ATOM 2596 C CB . ALA A 1 318 ? -0.173 67.709 -30.723 1.00 20.33 ? 317 ALA A CB 1 ATOM 2597 N N . THR A 1 319 ? -2.881 65.705 -30.399 1.00 19.02 ? 318 THR A N 1 ATOM 2598 C CA . THR A 1 319 ? -4.212 65.811 -29.757 1.00 16.15 ? 318 THR A CA 1 ATOM 2599 C C . THR A 1 319 ? -4.059 65.660 -28.256 1.00 19.06 ? 318 THR A C 1 ATOM 2600 O O . THR A 1 319 ? -4.593 66.443 -27.501 1.00 17.81 ? 318 THR A O 1 ATOM 2601 C CB . THR A 1 319 ? -5.190 64.749 -30.312 1.00 20.54 ? 318 THR A CB 1 ATOM 2602 O OG1 . THR A 1 319 ? -4.567 63.444 -30.275 1.00 21.84 ? 318 THR A OG1 1 ATOM 2603 C CG2 . THR A 1 319 ? -5.552 65.088 -31.741 1.00 21.92 ? 318 THR A CG2 1 ATOM 2604 N N . GLY A 1 320 ? -3.286 64.667 -27.847 1.00 17.54 ? 319 GLY A N 1 ATOM 2605 C CA . GLY A 1 320 ? -3.065 64.380 -26.436 1.00 18.94 ? 319 GLY A CA 1 ATOM 2606 C C . GLY A 1 320 ? -1.920 65.215 -25.836 1.00 20.19 ? 319 GLY A C 1 ATOM 2607 O O . GLY A 1 320 ? -1.467 66.220 -26.418 1.00 17.99 ? 319 GLY A O 1 ATOM 2608 N N . LEU A 1 321 ? -1.490 64.811 -24.635 1.00 21.97 ? 320 LEU A N 1 ATOM 2609 C CA . LEU A 1 321 ? -0.555 65.583 -23.810 1.00 21.42 ? 320 LEU A CA 1 ATOM 2610 C C . LEU A 1 321 ? 0.868 65.131 -24.040 1.00 23.80 ? 320 LEU A C 1 ATOM 2611 O O . LEU A 1 321 ? 1.110 64.017 -24.500 1.00 21.82 ? 320 LEU A O 1 ATOM 2612 C CB . LEU A 1 321 ? -0.864 65.238 -22.305 1.00 21.77 ? 320 LEU A CB 1 ATOM 2613 C CG . LEU A 1 321 ? -2.204 65.729 -21.762 1.00 23.42 ? 320 LEU A CG 1 ATOM 2614 C CD1 . LEU A 1 321 ? -3.408 64.965 -22.255 1.00 28.52 ? 320 LEU A CD1 1 ATOM 2615 C CD2 . LEU A 1 321 ? -2.211 65.690 -20.207 1.00 23.16 ? 320 LEU A CD2 1 ATOM 2616 N N A ARG A 1 322 ? 1.820 65.967 -23.648 0.34 19.16 ? 321 ARG A N 1 ATOM 2617 N N D ARG A 1 322 ? 1.814 65.980 -23.672 0.66 19.05 ? 321 ARG A N 1 ATOM 2618 C CA A ARG A 1 322 ? 3.214 65.538 -23.598 0.34 19.77 ? 321 ARG A CA 1 ATOM 2619 C CA D ARG A 1 322 ? 3.193 65.530 -23.584 0.66 19.62 ? 321 ARG A CA 1 ATOM 2620 C C A ARG A 1 322 ? 3.407 64.330 -22.648 0.34 25.95 ? 321 ARG A C 1 ATOM 2621 C C D ARG A 1 322 ? 3.265 64.274 -22.691 0.66 26.08 ? 321 ARG A C 1 ATOM 2622 O O A ARG A 1 322 ? 3.034 64.373 -21.474 0.34 21.83 ? 321 ARG A O 1 ATOM 2623 O O D ARG A 1 322 ? 2.624 64.211 -21.629 0.66 21.67 ? 321 ARG A O 1 ATOM 2624 C CB A ARG A 1 322 ? 4.113 66.715 -23.219 0.34 23.22 ? 321 ARG A CB 1 ATOM 2625 C CB D ARG A 1 322 ? 4.073 66.661 -23.068 0.66 23.12 ? 321 ARG A CB 1 ATOM 2626 C CG A ARG A 1 322 ? 5.487 66.281 -22.783 0.34 30.41 ? 321 ARG A CG 1 ATOM 2627 C CG D ARG A 1 322 ? 5.534 66.319 -23.062 0.66 32.48 ? 321 ARG A CG 1 ATOM 2628 C CD A ARG A 1 322 ? 6.325 67.460 -22.321 0.34 33.75 ? 321 ARG A CD 1 ATOM 2629 C CD D ARG A 1 322 ? 6.345 67.510 -22.571 0.66 34.99 ? 321 ARG A CD 1 ATOM 2630 N NE A ARG A 1 322 ? 7.078 68.049 -23.427 0.34 33.91 ? 321 ARG A NE 1 ATOM 2631 N NE D ARG A 1 322 ? 5.978 68.720 -23.296 0.66 25.67 ? 321 ARG A NE 1 ATOM 2632 C CZ A ARG A 1 322 ? 6.663 69.080 -24.160 0.34 34.43 ? 321 ARG A CZ 1 ATOM 2633 C CZ D ARG A 1 322 ? 6.754 69.345 -24.211 0.66 34.87 ? 321 ARG A CZ 1 ATOM 2634 N NH1 A ARG A 1 322 ? 5.477 69.656 -23.920 0.34 34.59 ? 321 ARG A NH1 1 ATOM 2635 N NH1 D ARG A 1 322 ? 7.970 68.876 -24.538 0.66 26.58 ? 321 ARG A NH1 1 ATOM 2636 N NH2 A ARG A 1 322 ? 7.446 69.546 -25.126 0.34 21.47 ? 321 ARG A NH2 1 ATOM 2637 N NH2 D ARG A 1 322 ? 6.308 70.469 -24.794 0.66 37.12 ? 321 ARG A NH2 1 ATOM 2638 N N . ASN A 1 323 ? 3.956 63.243 -23.189 1.00 22.10 ? 322 ASN A N 1 ATOM 2639 C CA . ASN A 1 323 ? 4.078 61.980 -22.482 1.00 23.84 ? 322 ASN A CA 1 ATOM 2640 C C . ASN A 1 323 ? 5.563 61.724 -22.170 1.00 30.10 ? 322 ASN A C 1 ATOM 2641 O O . ASN A 1 323 ? 6.341 61.349 -23.052 1.00 32.68 ? 322 ASN A O 1 ATOM 2642 C CB . ASN A 1 323 ? 3.554 60.841 -23.388 1.00 22.91 ? 322 ASN A CB 1 ATOM 2643 C CG . ASN A 1 323 ? 3.316 59.519 -22.598 1.00 25.17 ? 322 ASN A CG 1 ATOM 2644 O OD1 . ASN A 1 323 ? 2.831 59.527 -21.444 1.00 22.69 ? 322 ASN A OD1 1 ATOM 2645 N ND2 . ASN A 1 323 ? 3.638 58.399 -23.222 1.00 24.12 ? 322 ASN A ND2 1 ATOM 2646 N N . SER A 1 324 ? 5.957 61.943 -20.933 1.00 40.93 ? 323 SER A N 1 ATOM 2647 C CA . SER A 1 324 ? 7.388 61.809 -20.552 1.00 47.67 ? 323 SER A CA 1 ATOM 2648 C C . SER A 1 324 ? 7.677 60.452 -19.863 1.00 47.12 ? 323 SER A C 1 ATOM 2649 O O . SER A 1 324 ? 6.779 59.845 -19.260 1.00 49.29 ? 323 SER A O 1 ATOM 2650 C CB . SER A 1 324 ? 7.825 62.984 -19.646 1.00 46.13 ? 323 SER A CB 1 ATOM 2651 O OG . SER A 1 324 ? 7.625 64.272 -20.255 1.00 45.78 ? 323 SER A OG 1 ATOM 2652 N N . PRO A 1 325 ? 8.932 59.973 -19.938 1.00 55.39 ? 324 PRO A N 1 ATOM 2653 C CA . PRO A 1 325 ? 9.296 58.679 -19.323 1.00 63.23 ? 324 PRO A CA 1 ATOM 2654 C C . PRO A 1 325 ? 9.077 58.648 -17.808 1.00 53.08 ? 324 PRO A C 1 ATOM 2655 O O . PRO A 1 325 ? 9.285 59.716 -17.221 1.00 47.83 ? 324 PRO A O 1 ATOM 2656 C CB . PRO A 1 325 ? 10.797 58.550 -19.633 1.00 59.15 ? 324 PRO A CB 1 ATOM 2657 C CG . PRO A 1 325 ? 11.004 59.372 -20.858 1.00 61.68 ? 324 PRO A CG 1 ATOM 2658 C CD . PRO A 1 325 ? 10.053 60.556 -20.702 1.00 57.28 ? 324 PRO A CD 1 ATOM 2659 N N . GLY B 2 1 ? 6.693 73.512 -20.073 1.00 25.34 ? 1 GLY B N 1 ATOM 2660 C CA . GLY B 2 1 ? 5.652 74.162 -20.893 1.00 24.35 ? 1 GLY B CA 1 ATOM 2661 C C . GLY B 2 1 ? 5.337 75.569 -20.383 1.00 23.09 ? 1 GLY B C 1 ATOM 2662 O O . GLY B 2 1 ? 5.792 75.956 -19.285 1.00 21.97 ? 1 GLY B O 1 ATOM 2663 N N . LEU B 2 2 ? 4.548 76.346 -21.145 1.00 19.85 ? 2 LEU B N 1 ATOM 2664 C CA . LEU B 2 2 ? 4.400 77.780 -20.793 1.00 19.55 ? 2 LEU B CA 1 ATOM 2665 C C . LEU B 2 2 ? 3.751 77.961 -19.443 1.00 19.35 ? 2 LEU B C 1 ATOM 2666 O O . LEU B 2 2 ? 3.911 79.001 -18.814 1.00 19.17 ? 2 LEU B O 1 ATOM 2667 C CB . LEU B 2 2 ? 3.528 78.519 -21.832 1.00 19.93 ? 2 LEU B CB 1 ATOM 2668 C CG . LEU B 2 2 ? 4.119 78.706 -23.194 1.00 22.17 ? 2 LEU B CG 1 ATOM 2669 C CD1 . LEU B 2 2 ? 3.093 79.471 -24.065 1.00 22.47 ? 2 LEU B CD1 1 ATOM 2670 C CD2 . LEU B 2 2 ? 5.459 79.505 -23.037 1.00 18.92 ? 2 LEU B CD2 1 ATOM 2671 N N . PHE B 2 3 ? 2.944 76.982 -19.017 1.00 19.87 ? 3 PHE B N 1 ATOM 2672 C CA . PHE B 2 3 ? 2.173 77.208 -17.795 1.00 16.82 ? 3 PHE B CA 1 ATOM 2673 C C . PHE B 2 3 ? 2.740 76.549 -16.555 1.00 21.35 ? 3 PHE B C 1 ATOM 2674 O O . PHE B 2 3 ? 2.211 76.772 -15.437 1.00 24.35 ? 3 PHE B O 1 ATOM 2675 C CB . PHE B 2 3 ? 0.668 76.862 -18.049 1.00 18.01 ? 3 PHE B CB 1 ATOM 2676 C CG . PHE B 2 3 ? 0.054 77.790 -19.043 1.00 18.07 ? 3 PHE B CG 1 ATOM 2677 C CD1 . PHE B 2 3 ? 0.117 77.527 -20.430 1.00 21.90 ? 3 PHE B CD1 1 ATOM 2678 C CD2 . PHE B 2 3 ? -0.523 79.004 -18.606 1.00 17.96 ? 3 PHE B CD2 1 ATOM 2679 C CE1 . PHE B 2 3 ? -0.392 78.456 -21.351 1.00 19.57 ? 3 PHE B CE1 1 ATOM 2680 C CE2 . PHE B 2 3 ? -1.055 79.956 -19.578 1.00 19.81 ? 3 PHE B CE2 1 ATOM 2681 C CZ . PHE B 2 3 ? -0.971 79.673 -20.926 1.00 21.57 ? 3 PHE B CZ 1 ATOM 2682 N N . GLY B 2 4 ? 3.868 75.854 -16.735 1.00 22.01 ? 4 GLY B N 1 ATOM 2683 C CA . GLY B 2 4 ? 4.667 75.435 -15.583 1.00 22.82 ? 4 GLY B CA 1 ATOM 2684 C C . GLY B 2 4 ? 4.143 74.227 -14.796 1.00 23.92 ? 4 GLY B C 1 ATOM 2685 O O . GLY B 2 4 ? 4.728 73.876 -13.759 1.00 22.84 ? 4 GLY B O 1 ATOM 2686 N N . ALA B 2 5 ? 3.042 73.615 -15.247 1.00 20.11 ? 5 ALA B N 1 ATOM 2687 C CA . ALA B 2 5 ? 2.452 72.478 -14.525 1.00 19.17 ? 5 ALA B CA 1 ATOM 2688 C C . ALA B 2 5 ? 2.940 71.088 -14.987 1.00 23.39 ? 5 ALA B C 1 ATOM 2689 O O . ALA B 2 5 ? 3.560 70.321 -14.213 1.00 23.49 ? 5 ALA B O 1 ATOM 2690 C CB . ALA B 2 5 ? 0.855 72.572 -14.622 1.00 20.53 ? 5 ALA B CB 1 ATOM 2691 N N . ILE B 2 6 ? 2.608 70.738 -16.226 1.00 19.78 ? 6 ILE B N 1 ATOM 2692 C CA . ILE B 2 6 ? 2.985 69.421 -16.776 1.00 18.54 ? 6 ILE B CA 1 ATOM 2693 C C . ILE B 2 6 ? 4.517 69.363 -16.870 1.00 26.15 ? 6 ILE B C 1 ATOM 2694 O O . ILE B 2 6 ? 5.145 70.259 -17.448 1.00 23.70 ? 6 ILE B O 1 ATOM 2695 C CB . ILE B 2 6 ? 2.356 69.276 -18.157 1.00 22.80 ? 6 ILE B CB 1 ATOM 2696 C CG1 . ILE B 2 6 ? 0.868 69.015 -17.989 1.00 21.86 ? 6 ILE B CG1 1 ATOM 2697 C CG2 . ILE B 2 6 ? 2.981 68.064 -18.952 1.00 22.87 ? 6 ILE B CG2 1 ATOM 2698 C CD1 . ILE B 2 6 ? 0.131 68.942 -19.395 1.00 20.57 ? 6 ILE B CD1 1 ATOM 2699 N N . ALA B 2 7 ? 5.092 68.305 -16.300 1.00 23.64 ? 7 ALA B N 1 ATOM 2700 C CA . ALA B 2 7 ? 6.563 68.168 -16.207 1.00 29.87 ? 7 ALA B CA 1 ATOM 2701 C C . ALA B 2 7 ? 7.184 69.430 -15.675 1.00 30.26 ? 7 ALA B C 1 ATOM 2702 O O . ALA B 2 7 ? 8.250 69.901 -16.180 1.00 30.47 ? 7 ALA B O 1 ATOM 2703 C CB . ALA B 2 7 ? 7.168 67.839 -17.570 1.00 29.40 ? 7 ALA B CB 1 ATOM 2704 N N . GLY B 2 8 ? 6.505 70.026 -14.708 1.00 24.00 ? 8 GLY B N 1 ATOM 2705 C CA . GLY B 2 8 ? 6.903 71.286 -14.105 1.00 23.23 ? 8 GLY B CA 1 ATOM 2706 C C . GLY B 2 8 ? 6.804 71.067 -12.637 1.00 28.07 ? 8 GLY B C 1 ATOM 2707 O O . GLY B 2 8 ? 7.488 70.168 -12.126 1.00 29.00 ? 8 GLY B O 1 ATOM 2708 N N . PHE B 2 9 ? 5.937 71.817 -11.953 1.00 25.53 ? 9 PHE B N 1 ATOM 2709 C CA . PHE B 2 9 ? 5.767 71.537 -10.529 1.00 27.36 ? 9 PHE B CA 1 ATOM 2710 C C . PHE B 2 9 ? 5.091 70.196 -10.279 1.00 27.34 ? 9 PHE B C 1 ATOM 2711 O O . PHE B 2 9 ? 5.214 69.656 -9.199 1.00 26.85 ? 9 PHE B O 1 ATOM 2712 C CB . PHE B 2 9 ? 5.146 72.674 -9.712 1.00 24.76 ? 9 PHE B CB 1 ATOM 2713 C CG . PHE B 2 9 ? 3.680 72.862 -9.951 1.00 21.79 ? 9 PHE B CG 1 ATOM 2714 C CD1 . PHE B 2 9 ? 2.744 72.223 -9.149 1.00 32.07 ? 9 PHE B CD1 1 ATOM 2715 C CD2 . PHE B 2 9 ? 3.224 73.663 -10.996 1.00 27.90 ? 9 PHE B CD2 1 ATOM 2716 C CE1 . PHE B 2 9 ? 1.357 72.411 -9.408 1.00 30.15 ? 9 PHE B CE1 1 ATOM 2717 C CE2 . PHE B 2 9 ? 1.862 73.834 -11.247 1.00 32.99 ? 9 PHE B CE2 1 ATOM 2718 C CZ . PHE B 2 9 ? 0.938 73.191 -10.465 1.00 35.61 ? 9 PHE B CZ 1 ATOM 2719 N N . ILE B 2 10 ? 4.402 69.667 -11.290 1.00 22.81 ? 10 ILE B N 1 ATOM 2720 C CA . ILE B 2 10 ? 3.829 68.319 -11.161 1.00 23.83 ? 10 ILE B CA 1 ATOM 2721 C C . ILE B 2 10 ? 4.798 67.470 -11.971 1.00 25.94 ? 10 ILE B C 1 ATOM 2722 O O . ILE B 2 10 ? 4.855 67.583 -13.190 1.00 25.87 ? 10 ILE B O 1 ATOM 2723 C CB . ILE B 2 10 ? 2.406 68.238 -11.720 1.00 21.02 ? 10 ILE B CB 1 ATOM 2724 C CG1 . ILE B 2 10 ? 1.535 69.246 -10.941 1.00 24.61 ? 10 ILE B CG1 1 ATOM 2725 C CG2 . ILE B 2 10 ? 1.836 66.758 -11.601 1.00 21.73 ? 10 ILE B CG2 1 ATOM 2726 C CD1 . ILE B 2 10 ? 0.114 69.371 -11.470 1.00 28.98 ? 10 ILE B CD1 1 ATOM 2727 N N . GLU B 2 11 ? 5.540 66.609 -11.274 1.00 24.80 ? 11 GLU B N 1 ATOM 2728 C CA . GLU B 2 11 ? 6.750 66.041 -11.868 1.00 34.70 ? 11 GLU B CA 1 ATOM 2729 C C . GLU B 2 11 ? 6.471 65.150 -13.067 1.00 33.40 ? 11 GLU B C 1 ATOM 2730 O O . GLU B 2 11 ? 7.243 65.131 -14.008 1.00 32.32 ? 11 GLU B O 1 ATOM 2731 C CB . GLU B 2 11 ? 7.481 65.203 -10.810 1.00 36.65 ? 11 GLU B CB 1 ATOM 2732 C CG . GLU B 2 11 ? 8.966 65.428 -10.790 1.00 74.52 ? 11 GLU B CG 1 ATOM 2733 C CD . GLU B 2 11 ? 9.406 66.063 -9.484 1.00 87.35 ? 11 GLU B CD 1 ATOM 2734 O OE1 . GLU B 2 11 ? 9.117 65.456 -8.423 1.00 79.16 ? 11 GLU B OE1 1 ATOM 2735 O OE2 . GLU B 2 11 ? 10.012 67.165 -9.518 1.00 86.69 ? 11 GLU B OE2 1 ATOM 2736 N N . GLY B 2 12 ? 5.354 64.431 -13.043 1.00 26.59 ? 12 GLY B N 1 ATOM 2737 C CA . GLY B 2 12 ? 5.041 63.520 -14.134 1.00 26.59 ? 12 GLY B CA 1 ATOM 2738 C C . GLY B 2 12 ? 3.555 63.201 -14.177 1.00 25.35 ? 12 GLY B C 1 ATOM 2739 O O . GLY B 2 12 ? 2.807 63.631 -13.288 1.00 21.63 ? 12 GLY B O 1 ATOM 2740 N N . GLY B 2 13 ? 3.140 62.469 -15.216 1.00 23.42 ? 13 GLY B N 1 ATOM 2741 C CA . GLY B 2 13 ? 1.749 62.088 -15.387 1.00 19.26 ? 13 GLY B CA 1 ATOM 2742 C C . GLY B 2 13 ? 1.464 60.756 -14.676 1.00 21.30 ? 13 GLY B C 1 ATOM 2743 O O . GLY B 2 13 ? 2.370 60.100 -14.140 1.00 25.08 ? 13 GLY B O 1 ATOM 2744 N N . TRP B 2 14 ? 0.188 60.415 -14.649 1.00 19.55 ? 14 TRP B N 1 ATOM 2745 C CA . TRP B 2 14 ? -0.294 59.198 -13.981 1.00 19.91 ? 14 TRP B CA 1 ATOM 2746 C C . TRP B 2 14 ? -0.766 58.153 -14.982 1.00 23.50 ? 14 TRP B C 1 ATOM 2747 O O . TRP B 2 14 ? -1.794 58.324 -15.663 1.00 21.07 ? 14 TRP B O 1 ATOM 2748 C CB . TRP B 2 14 ? -1.460 59.551 -13.085 1.00 20.45 ? 14 TRP B CB 1 ATOM 2749 C CG . TRP B 2 14 ? -1.140 60.436 -11.882 1.00 20.68 ? 14 TRP B CG 1 ATOM 2750 C CD1 . TRP B 2 14 ? 0.012 60.503 -11.209 1.00 25.12 ? 14 TRP B CD1 1 ATOM 2751 C CD2 . TRP B 2 14 ? -2.059 61.322 -11.224 1.00 21.64 ? 14 TRP B CD2 1 ATOM 2752 N NE1 . TRP B 2 14 ? -0.115 61.366 -10.116 1.00 24.74 ? 14 TRP B NE1 1 ATOM 2753 C CE2 . TRP B 2 14 ? -1.386 61.878 -10.115 1.00 24.05 ? 14 TRP B CE2 1 ATOM 2754 C CE3 . TRP B 2 14 ? -3.396 61.673 -11.450 1.00 20.96 ? 14 TRP B CE3 1 ATOM 2755 C CZ2 . TRP B 2 14 ? -1.980 62.796 -9.271 1.00 22.18 ? 14 TRP B CZ2 1 ATOM 2756 C CZ3 . TRP B 2 14 ? -4.027 62.595 -10.576 1.00 22.33 ? 14 TRP B CZ3 1 ATOM 2757 C CH2 . TRP B 2 14 ? -3.312 63.117 -9.478 1.00 21.25 ? 14 TRP B CH2 1 ATOM 2758 N N . GLN B 2 15 ? -0.055 57.024 -15.048 1.00 23.38 ? 15 GLN B N 1 ATOM 2759 C CA . GLN B 2 15 ? -0.580 55.922 -15.879 1.00 23.13 ? 15 GLN B CA 1 ATOM 2760 C C . GLN B 2 15 ? -1.921 55.460 -15.368 1.00 23.19 ? 15 GLN B C 1 ATOM 2761 O O . GLN B 2 15 ? -2.758 54.874 -16.121 1.00 25.70 ? 15 GLN B O 1 ATOM 2762 C CB . GLN B 2 15 ? 0.399 54.738 -15.758 1.00 22.39 ? 15 GLN B CB 1 ATOM 2763 C CG . GLN B 2 15 ? 1.815 55.013 -16.251 1.00 32.04 ? 15 GLN B CG 1 ATOM 2764 C CD . GLN B 2 15 ? 1.957 55.094 -17.767 1.00 31.01 ? 15 GLN B CD 1 ATOM 2765 O OE1 . GLN B 2 15 ? 1.373 54.298 -18.515 1.00 31.13 ? 15 GLN B OE1 1 ATOM 2766 N NE2 . GLN B 2 15 ? 2.735 56.073 -18.234 1.00 37.52 ? 15 GLN B NE2 1 ATOM 2767 N N . GLY B 2 16 ? -2.164 55.677 -14.085 1.00 22.34 ? 16 GLY B N 1 ATOM 2768 C CA . GLY B 2 16 ? -3.429 55.256 -13.473 1.00 29.11 ? 16 GLY B CA 1 ATOM 2769 C C . GLY B 2 16 ? -4.660 56.092 -13.764 1.00 31.36 ? 16 GLY B C 1 ATOM 2770 O O . GLY B 2 16 ? -5.757 55.735 -13.424 1.00 29.98 ? 16 GLY B O 1 ATOM 2771 N N . MET B 2 17 ? -4.474 57.218 -14.427 1.00 23.32 ? 17 MET B N 1 ATOM 2772 C CA . MET B 2 17 ? -5.603 58.032 -14.733 1.00 28.18 ? 17 MET B CA 1 ATOM 2773 C C . MET B 2 17 ? -6.018 57.891 -16.189 1.00 23.42 ? 17 MET B C 1 ATOM 2774 O O . MET B 2 17 ? -5.468 58.488 -17.127 1.00 26.13 ? 17 MET B O 1 ATOM 2775 C CB . MET B 2 17 ? -5.342 59.449 -14.337 1.00 36.93 ? 17 MET B CB 1 ATOM 2776 C CG . MET B 2 17 ? -6.454 59.940 -13.453 1.00 47.27 ? 17 MET B CG 1 ATOM 2777 S SD . MET B 2 17 ? -7.442 60.933 -14.532 1.00 37.52 ? 17 MET B SD 1 ATOM 2778 C CE . MET B 2 17 ? -6.009 61.724 -15.340 1.00 40.18 ? 17 MET B CE 1 ATOM 2779 N N . VAL B 2 18 ? -6.988 56.999 -16.329 1.00 28.37 ? 18 VAL B N 1 ATOM 2780 C CA . VAL B 2 18 ? -7.354 56.455 -17.626 1.00 22.25 ? 18 VAL B CA 1 ATOM 2781 C C . VAL B 2 18 ? -8.637 57.083 -18.106 1.00 22.20 ? 18 VAL B C 1 ATOM 2782 O O . VAL B 2 18 ? -8.836 57.206 -19.338 1.00 27.09 ? 18 VAL B O 1 ATOM 2783 C CB . VAL B 2 18 ? -7.553 54.910 -17.418 1.00 30.70 ? 18 VAL B CB 1 ATOM 2784 C CG1 . VAL B 2 18 ? -8.325 54.315 -18.522 1.00 37.53 ? 18 VAL B CG1 1 ATOM 2785 C CG2 . VAL B 2 18 ? -6.198 54.253 -17.156 1.00 29.04 ? 18 VAL B CG2 1 ATOM 2786 N N . ASP B 2 19 ? -9.475 57.612 -17.210 1.00 20.28 ? 19 ASP B N 1 ATOM 2787 C CA . ASP B 2 19 ? -10.791 58.081 -17.633 1.00 19.53 ? 19 ASP B CA 1 ATOM 2788 C C . ASP B 2 19 ? -10.930 59.625 -17.730 1.00 17.68 ? 19 ASP B C 1 ATOM 2789 O O . ASP B 2 19 ? -12.032 60.156 -17.776 1.00 20.52 ? 19 ASP B O 1 ATOM 2790 C CB . ASP B 2 19 ? -11.943 57.474 -16.810 1.00 19.64 ? 19 ASP B CB 1 ATOM 2791 C CG . ASP B 2 19 ? -11.884 57.848 -15.351 1.00 27.14 ? 19 ASP B CG 1 ATOM 2792 O OD1 . ASP B 2 19 ? -10.973 58.590 -14.967 1.00 23.35 ? 19 ASP B OD1 1 ATOM 2793 O OD2 . ASP B 2 19 ? -12.727 57.378 -14.570 1.00 27.24 ? 19 ASP B OD2 1 ATOM 2794 N N . GLY B 2 20 ? -9.762 60.273 -17.771 1.00 19.89 ? 20 GLY B N 1 ATOM 2795 C CA . GLY B 2 20 ? -9.747 61.726 -17.999 1.00 20.52 ? 20 GLY B CA 1 ATOM 2796 C C . GLY B 2 20 ? -8.364 62.142 -18.447 1.00 19.17 ? 20 GLY B C 1 ATOM 2797 O O . GLY B 2 20 ? -7.419 61.339 -18.300 1.00 22.00 ? 20 GLY B O 1 ATOM 2798 N N . TRP B 2 21 ? -8.248 63.353 -19.035 1.00 17.61 ? 21 TRP B N 1 ATOM 2799 C CA . TRP B 2 21 ? -6.943 63.853 -19.342 1.00 18.36 ? 21 TRP B CA 1 ATOM 2800 C C . TRP B 2 21 ? -6.337 64.529 -18.101 1.00 18.13 ? 21 TRP B C 1 ATOM 2801 O O . TRP B 2 21 ? -5.086 64.555 -18.007 1.00 19.64 ? 21 TRP B O 1 ATOM 2802 C CB . TRP B 2 21 ? -7.055 64.904 -20.479 1.00 17.73 ? 21 TRP B CB 1 ATOM 2803 C CG . TRP B 2 21 ? -7.017 64.328 -21.857 1.00 20.16 ? 21 TRP B CG 1 ATOM 2804 C CD1 . TRP B 2 21 ? -6.600 63.080 -22.213 1.00 22.83 ? 21 TRP B CD1 1 ATOM 2805 C CD2 . TRP B 2 21 ? -7.342 65.020 -23.055 1.00 19.36 ? 21 TRP B CD2 1 ATOM 2806 N NE1 . TRP B 2 21 ? -6.662 62.957 -23.627 1.00 23.05 ? 21 TRP B NE1 1 ATOM 2807 C CE2 . TRP B 2 21 ? -7.142 64.133 -24.139 1.00 22.99 ? 21 TRP B CE2 1 ATOM 2808 C CE3 . TRP B 2 21 ? -7.853 66.278 -23.302 1.00 18.66 ? 21 TRP B CE3 1 ATOM 2809 C CZ2 . TRP B 2 21 ? -7.358 64.520 -25.483 1.00 22.21 ? 21 TRP B CZ2 1 ATOM 2810 C CZ3 . TRP B 2 21 ? -8.083 66.665 -24.625 1.00 19.57 ? 21 TRP B CZ3 1 ATOM 2811 C CH2 . TRP B 2 21 ? -7.850 65.780 -25.678 1.00 20.45 ? 21 TRP B CH2 1 ATOM 2812 N N . TYR B 2 22 ? -7.214 65.080 -17.232 1.00 18.93 ? 22 TYR B N 1 ATOM 2813 C CA . TYR B 2 22 ? -6.765 65.779 -16.005 1.00 19.24 ? 22 TYR B CA 1 ATOM 2814 C C . TYR B 2 22 ? -7.646 65.307 -14.887 1.00 19.11 ? 22 TYR B C 1 ATOM 2815 O O . TYR B 2 22 ? -8.831 64.983 -15.078 1.00 20.20 ? 22 TYR B O 1 ATOM 2816 C CB . TYR B 2 22 ? -6.964 67.294 -16.157 1.00 17.79 ? 22 TYR B CB 1 ATOM 2817 C CG . TYR B 2 22 ? -6.753 67.801 -17.580 1.00 15.79 ? 22 TYR B CG 1 ATOM 2818 C CD1 . TYR B 2 22 ? -5.461 67.760 -18.199 1.00 18.29 ? 22 TYR B CD1 1 ATOM 2819 C CD2 . TYR B 2 22 ? -7.823 68.335 -18.286 1.00 17.35 ? 22 TYR B CD2 1 ATOM 2820 C CE1 . TYR B 2 22 ? -5.278 68.234 -19.512 1.00 20.85 ? 22 TYR B CE1 1 ATOM 2821 C CE2 . TYR B 2 22 ? -7.658 68.806 -19.597 1.00 17.89 ? 22 TYR B CE2 1 ATOM 2822 C CZ . TYR B 2 22 ? -6.375 68.758 -20.174 1.00 19.35 ? 22 TYR B CZ 1 ATOM 2823 O OH . TYR B 2 22 ? -6.212 69.212 -21.429 1.00 17.42 ? 22 TYR B OH 1 ATOM 2824 N N . GLY B 2 23 ? -7.105 65.251 -13.678 1.00 18.86 ? 23 GLY B N 1 ATOM 2825 C CA . GLY B 2 23 ? -7.955 64.755 -12.602 1.00 19.65 ? 23 GLY B CA 1 ATOM 2826 C C . GLY B 2 23 ? -7.215 64.746 -11.263 1.00 18.29 ? 23 GLY B C 1 ATOM 2827 O O . GLY B 2 23 ? -6.227 65.496 -11.086 1.00 18.88 ? 23 GLY B O 1 ATOM 2828 N N . TYR B 2 24 ? -7.646 63.868 -10.343 1.00 19.63 ? 24 TYR B N 1 ATOM 2829 C CA . TYR B 2 24 ? -7.238 63.979 -8.963 1.00 23.37 ? 24 TYR B CA 1 ATOM 2830 C C . TYR B 2 24 ? -6.845 62.618 -8.430 1.00 26.43 ? 24 TYR B C 1 ATOM 2831 O O . TYR B 2 24 ? -7.280 61.592 -8.946 1.00 23.83 ? 24 TYR B O 1 ATOM 2832 C CB . TYR B 2 24 ? -8.473 64.393 -8.156 1.00 20.83 ? 24 TYR B CB 1 ATOM 2833 C CG . TYR B 2 24 ? -9.216 65.575 -8.668 1.00 22.95 ? 24 TYR B CG 1 ATOM 2834 C CD1 . TYR B 2 24 ? -8.906 66.850 -8.222 1.00 22.02 ? 24 TYR B CD1 1 ATOM 2835 C CD2 . TYR B 2 24 ? -10.283 65.428 -9.599 1.00 20.85 ? 24 TYR B CD2 1 ATOM 2836 C CE1 . TYR B 2 24 ? -9.609 67.966 -8.674 1.00 19.22 ? 24 TYR B CE1 1 ATOM 2837 C CE2 . TYR B 2 24 ? -10.993 66.541 -10.022 1.00 18.72 ? 24 TYR B CE2 1 ATOM 2838 C CZ . TYR B 2 24 ? -10.680 67.792 -9.579 1.00 22.28 ? 24 TYR B CZ 1 ATOM 2839 O OH . TYR B 2 24 ? -11.418 68.870 -10.038 1.00 25.36 ? 24 TYR B OH 1 ATOM 2840 N N . HIS B 2 25 ? -6.023 62.615 -7.397 1.00 20.39 ? 25 HIS B N 1 ATOM 2841 C CA . HIS B 2 25 ? -5.810 61.383 -6.651 1.00 21.01 ? 25 HIS B CA 1 ATOM 2842 C C . HIS B 2 25 ? -5.999 61.775 -5.195 1.00 29.70 ? 25 HIS B C 1 ATOM 2843 O O . HIS B 2 25 ? -5.437 62.807 -4.770 1.00 23.34 ? 25 HIS B O 1 ATOM 2844 C CB . HIS B 2 25 ? -4.432 60.850 -6.854 1.00 22.12 ? 25 HIS B CB 1 ATOM 2845 C CG . HIS B 2 25 ? -4.201 59.540 -6.144 1.00 25.14 ? 25 HIS B CG 1 ATOM 2846 N ND1 . HIS B 2 25 ? -3.765 59.466 -4.834 1.00 27.33 ? 25 HIS B ND1 1 ATOM 2847 C CD2 . HIS B 2 25 ? -4.402 58.260 -6.555 1.00 26.42 ? 25 HIS B CD2 1 ATOM 2848 C CE1 . HIS B 2 25 ? -3.676 58.185 -4.479 1.00 30.72 ? 25 HIS B CE1 1 ATOM 2849 N NE2 . HIS B 2 25 ? -4.100 57.437 -5.489 1.00 26.29 ? 25 HIS B NE2 1 ATOM 2850 N N . HIS B 2 26 ? -6.795 61.014 -4.432 1.00 21.83 ? 26 HIS B N 1 ATOM 2851 C CA . HIS B 2 26 ? -6.993 61.423 -3.027 1.00 22.63 ? 26 HIS B CA 1 ATOM 2852 C C . HIS B 2 26 ? -6.623 60.290 -2.104 1.00 26.48 ? 26 HIS B C 1 ATOM 2853 O O . HIS B 2 26 ? -6.495 59.119 -2.535 1.00 28.27 ? 26 HIS B O 1 ATOM 2854 C CB . HIS B 2 26 ? -8.444 61.795 -2.699 1.00 26.04 ? 26 HIS B CB 1 ATOM 2855 C CG . HIS B 2 26 ? -9.361 60.602 -2.723 1.00 29.96 ? 26 HIS B CG 1 ATOM 2856 N ND1 . HIS B 2 26 ? -9.837 60.064 -3.899 1.00 30.07 ? 26 HIS B ND1 1 ATOM 2857 C CD2 . HIS B 2 26 ? -9.768 59.758 -1.729 1.00 32.03 ? 26 HIS B CD2 1 ATOM 2858 C CE1 . HIS B 2 26 ? -10.569 58.988 -3.636 1.00 31.52 ? 26 HIS B CE1 1 ATOM 2859 N NE2 . HIS B 2 26 ? -10.542 58.781 -2.324 1.00 32.48 ? 26 HIS B NE2 1 ATOM 2860 N N . SER B 2 27 ? -6.435 60.668 -0.841 1.00 23.25 ? 27 SER B N 1 ATOM 2861 C CA . SER B 2 27 ? -6.188 59.640 0.195 1.00 25.76 ? 27 SER B CA 1 ATOM 2862 C C . SER B 2 27 ? -6.737 60.114 1.502 1.00 30.94 ? 27 SER B C 1 ATOM 2863 O O . SER B 2 27 ? -6.504 61.267 1.931 1.00 27.42 ? 27 SER B O 1 ATOM 2864 C CB . SER B 2 27 ? -4.706 59.227 0.293 1.00 29.21 ? 27 SER B CB 1 ATOM 2865 O OG . SER B 2 27 ? -3.897 60.348 0.518 1.00 53.59 ? 27 SER B OG 1 ATOM 2866 N N . ASN B 2 28 ? -7.546 59.266 2.134 1.00 27.20 ? 28 ASN B N 1 ATOM 2867 C CA . ASN B 2 28 ? -8.167 59.685 3.399 1.00 25.07 ? 28 ASN B CA 1 ATOM 2868 C C . ASN B 2 28 ? -8.396 58.383 4.183 1.00 34.40 ? 28 ASN B C 1 ATOM 2869 O O . ASN B 2 28 ? -7.881 57.346 3.801 1.00 29.81 ? 28 ASN B O 1 ATOM 2870 C CB . ASN B 2 28 ? -9.457 60.494 3.237 1.00 23.50 ? 28 ASN B CB 1 ATOM 2871 C CG . ASN B 2 28 ? -10.530 59.752 2.422 1.00 24.21 ? 28 ASN B CG 1 ATOM 2872 O OD1 . ASN B 2 28 ? -10.405 58.533 2.249 1.00 29.45 ? 28 ASN B OD1 1 ATOM 2873 N ND2 . ASN B 2 28 ? -11.560 60.458 1.920 1.00 24.96 ? 28 ASN B ND2 1 ATOM 2874 N N . GLU B 2 29 ? -9.145 58.460 5.251 1.00 34.23 ? 29 GLU B N 1 ATOM 2875 C CA . GLU B 2 29 ? -9.276 57.278 6.127 1.00 41.35 ? 29 GLU B CA 1 ATOM 2876 C C . GLU B 2 29 ? -9.965 56.166 5.360 1.00 39.19 ? 29 GLU B C 1 ATOM 2877 O O . GLU B 2 29 ? -9.617 54.995 5.511 1.00 44.00 ? 29 GLU B O 1 ATOM 2878 C CB . GLU B 2 29 ? -10.078 57.639 7.370 1.00 40.08 ? 29 GLU B CB 1 ATOM 2879 C CG . GLU B 2 29 ? -9.538 57.029 8.654 1.00 68.55 ? 29 GLU B CG 1 ATOM 2880 C CD . GLU B 2 29 ? -10.536 57.125 9.802 1.00 73.57 ? 29 GLU B CD 1 ATOM 2881 O OE1 . GLU B 2 29 ? -10.679 58.220 10.405 1.00 78.63 ? 29 GLU B OE1 1 ATOM 2882 O OE2 . GLU B 2 29 ? -11.190 56.096 10.090 1.00 80.37 ? 29 GLU B OE2 1 ATOM 2883 N N . GLN B 2 30 ? -10.937 56.537 4.530 1.00 35.71 ? 30 GLN B N 1 ATOM 2884 C CA . GLN B 2 30 ? -11.687 55.582 3.689 1.00 36.22 ? 30 GLN B CA 1 ATOM 2885 C C . GLN B 2 30 ? -10.912 54.872 2.597 1.00 41.94 ? 30 GLN B C 1 ATOM 2886 O O . GLN B 2 30 ? -11.359 53.827 2.108 1.00 40.81 ? 30 GLN B O 1 ATOM 2887 C CB . GLN B 2 30 ? -12.929 56.248 3.104 1.00 33.31 ? 30 GLN B CB 1 ATOM 2888 C CG . GLN B 2 30 ? -13.955 56.583 4.161 1.00 33.88 ? 30 GLN B CG 1 ATOM 2889 C CD . GLN B 2 30 ? -14.969 57.572 3.685 1.00 44.56 ? 30 GLN B CD 1 ATOM 2890 O OE1 . GLN B 2 30 ? -14.640 58.717 3.380 1.00 42.09 ? 30 GLN B OE1 1 ATOM 2891 N NE2 . GLN B 2 30 ? -16.203 57.147 3.589 1.00 39.93 ? 30 GLN B NE2 1 ATOM 2892 N N . GLY B 2 31 ? -9.760 55.413 2.202 1.00 33.00 ? 31 GLY B N 1 ATOM 2893 C CA . GLY B 2 31 ? -8.905 54.779 1.207 1.00 33.96 ? 31 GLY B CA 1 ATOM 2894 C C . GLY B 2 31 ? -8.357 55.796 0.214 1.00 37.22 ? 31 GLY B C 1 ATOM 2895 O O . GLY B 2 31 ? -8.346 56.987 0.512 1.00 30.35 ? 31 GLY B O 1 ATOM 2896 N N . SER B 2 32 ? -7.915 55.344 -0.951 1.00 37.53 ? 32 SER B N 1 ATOM 2897 C CA . SER B 2 32 ? -7.317 56.269 -1.918 1.00 31.17 ? 32 SER B CA 1 ATOM 2898 C C . SER B 2 32 ? -7.717 55.888 -3.316 1.00 38.50 ? 32 SER B C 1 ATOM 2899 O O . SER B 2 32 ? -8.090 54.747 -3.578 1.00 35.17 ? 32 SER B O 1 ATOM 2900 C CB . SER B 2 32 ? -5.800 56.207 -1.855 1.00 30.51 ? 32 SER B CB 1 ATOM 2901 O OG . SER B 2 32 ? -5.345 54.880 -2.125 1.00 40.07 ? 32 SER B OG 1 ATOM 2902 N N . GLY B 2 33 ? -7.588 56.817 -4.250 1.00 28.31 ? 33 GLY B N 1 ATOM 2903 C CA . GLY B 2 33 ? -7.903 56.447 -5.618 1.00 28.96 ? 33 GLY B CA 1 ATOM 2904 C C . GLY B 2 33 ? -7.884 57.636 -6.544 1.00 28.39 ? 33 GLY B C 1 ATOM 2905 O O . GLY B 2 33 ? -7.748 58.811 -6.094 1.00 26.71 ? 33 GLY B O 1 ATOM 2906 N N . TYR B 2 34 ? -7.968 57.327 -7.827 1.00 25.42 ? 34 TYR B N 1 ATOM 2907 C CA . TYR B 2 34 ? -8.030 58.356 -8.881 1.00 26.27 ? 34 TYR B CA 1 ATOM 2908 C C . TYR B 2 34 ? -9.456 58.762 -9.242 1.00 35.28 ? 34 TYR B C 1 ATOM 2909 O O . TYR B 2 34 ? -10.415 57.970 -9.151 1.00 29.37 ? 34 TYR B O 1 ATOM 2910 C CB . TYR B 2 34 ? -7.326 57.829 -10.159 1.00 25.45 ? 34 TYR B CB 1 ATOM 2911 C CG . TYR B 2 34 ? -5.874 57.521 -10.002 1.00 26.99 ? 34 TYR B CG 1 ATOM 2912 C CD1 . TYR B 2 34 ? -5.434 56.221 -9.714 1.00 25.27 ? 34 TYR B CD1 1 ATOM 2913 C CD2 . TYR B 2 34 ? -4.927 58.512 -10.123 1.00 27.14 ? 34 TYR B CD2 1 ATOM 2914 C CE1 . TYR B 2 34 ? -4.134 55.948 -9.558 1.00 28.67 ? 34 TYR B CE1 1 ATOM 2915 C CE2 . TYR B 2 34 ? -3.598 58.235 -9.960 1.00 26.89 ? 34 TYR B CE2 1 ATOM 2916 C CZ . TYR B 2 34 ? -3.220 56.929 -9.680 1.00 28.77 ? 34 TYR B CZ 1 ATOM 2917 O OH . TYR B 2 34 ? -1.910 56.646 -9.517 1.00 29.81 ? 34 TYR B OH 1 ATOM 2918 N N . ALA B 2 35 ? -9.626 59.994 -9.706 1.00 21.81 ? 35 ALA B N 1 ATOM 2919 C CA . ALA B 2 35 ? -10.898 60.372 -10.283 1.00 25.05 ? 35 ALA B CA 1 ATOM 2920 C C . ALA B 2 35 ? -10.640 61.407 -11.350 1.00 29.19 ? 35 ALA B C 1 ATOM 2921 O O . ALA B 2 35 ? -9.923 62.388 -11.126 1.00 23.47 ? 35 ALA B O 1 ATOM 2922 C CB . ALA B 2 35 ? -11.854 60.949 -9.247 1.00 30.03 ? 35 ALA B CB 1 ATOM 2923 N N . ALA B 2 36 ? -11.287 61.252 -12.498 1.00 25.63 ? 36 ALA B N 1 ATOM 2924 C CA . ALA B 2 36 ? -11.129 62.258 -13.566 1.00 23.06 ? 36 ALA B CA 1 ATOM 2925 C C . ALA B 2 36 ? -11.774 63.598 -13.198 1.00 23.25 ? 36 ALA B C 1 ATOM 2926 O O . ALA B 2 36 ? -12.808 63.615 -12.543 1.00 25.58 ? 36 ALA B O 1 ATOM 2927 C CB . ALA B 2 36 ? -11.838 61.720 -14.825 1.00 27.92 ? 36 ALA B CB 1 ATOM 2928 N N . ASP B 2 37 ? -11.228 64.725 -13.682 1.00 20.06 ? 37 ASP B N 1 ATOM 2929 C CA . ASP B 2 37 ? -12.038 65.955 -13.755 1.00 19.95 ? 37 ASP B CA 1 ATOM 2930 C C . ASP B 2 37 ? -12.754 65.986 -15.103 1.00 22.72 ? 37 ASP B C 1 ATOM 2931 O O . ASP B 2 37 ? -12.155 66.257 -16.154 1.00 19.68 ? 37 ASP B O 1 ATOM 2932 C CB . ASP B 2 37 ? -11.217 67.236 -13.597 1.00 23.08 ? 37 ASP B CB 1 ATOM 2933 C CG . ASP B 2 37 ? -12.119 68.425 -13.417 1.00 26.66 ? 37 ASP B CG 1 ATOM 2934 O OD1 . ASP B 2 37 ? -12.704 68.564 -12.294 1.00 26.56 ? 37 ASP B OD1 1 ATOM 2935 O OD2 . ASP B 2 37 ? -12.359 69.155 -14.407 1.00 25.45 ? 37 ASP B OD2 1 ATOM 2936 N N . LYS B 2 38 ? -14.015 65.576 -15.111 1.00 22.87 ? 38 LYS B N 1 ATOM 2937 C CA A LYS B 2 38 ? -14.635 65.356 -16.421 0.50 23.25 ? 38 LYS B CA 1 ATOM 2938 C CA B LYS B 2 38 ? -14.657 65.357 -16.410 0.50 23.27 ? 38 LYS B CA 1 ATOM 2939 C C . LYS B 2 38 ? -14.934 66.669 -17.143 1.00 22.50 ? 38 LYS B C 1 ATOM 2940 O O . LYS B 2 38 ? -14.935 66.715 -18.369 1.00 21.04 ? 38 LYS B O 1 ATOM 2941 C CB A LYS B 2 38 ? -15.883 64.470 -16.318 0.50 30.30 ? 38 LYS B CB 1 ATOM 2942 C CB B LYS B 2 38 ? -15.933 64.515 -16.265 0.50 30.28 ? 38 LYS B CB 1 ATOM 2943 C CG A LYS B 2 38 ? -16.984 65.042 -15.491 0.50 33.39 ? 38 LYS B CG 1 ATOM 2944 C CG B LYS B 2 38 ? -17.132 65.232 -15.702 0.50 33.26 ? 38 LYS B CG 1 ATOM 2945 C CD A LYS B 2 38 ? -18.117 64.007 -15.269 0.50 34.22 ? 38 LYS B CD 1 ATOM 2946 C CD B LYS B 2 38 ? -18.272 64.207 -15.429 0.50 32.32 ? 38 LYS B CD 1 ATOM 2947 C CE A LYS B 2 38 ? -19.286 64.641 -14.514 0.50 31.69 ? 38 LYS B CE 1 ATOM 2948 C CE B LYS B 2 38 ? -17.920 63.285 -14.246 0.50 31.76 ? 38 LYS B CE 1 ATOM 2949 N NZ A LYS B 2 38 ? -20.285 65.246 -15.462 0.50 42.53 ? 38 LYS B NZ 1 ATOM 2950 N NZ B LYS B 2 38 ? -18.087 63.952 -12.884 0.50 35.73 ? 38 LYS B NZ 1 ATOM 2951 N N . GLU B 2 39 ? -15.178 67.751 -16.400 1.00 22.61 ? 39 GLU B N 1 ATOM 2952 C CA A GLU B 2 39 ? -15.490 69.036 -17.016 0.43 25.03 ? 39 GLU B CA 1 ATOM 2953 C CA B GLU B 2 39 ? -15.510 69.031 -17.026 0.57 24.96 ? 39 GLU B CA 1 ATOM 2954 C C . GLU B 2 39 ? -14.333 69.616 -17.802 1.00 25.64 ? 39 GLU B C 1 ATOM 2955 O O . GLU B 2 39 ? -14.488 70.015 -18.935 1.00 21.96 ? 39 GLU B O 1 ATOM 2956 C CB A GLU B 2 39 ? -15.894 70.048 -15.949 0.43 30.19 ? 39 GLU B CB 1 ATOM 2957 C CB B GLU B 2 39 ? -16.010 70.037 -15.968 0.57 30.17 ? 39 GLU B CB 1 ATOM 2958 C CG A GLU B 2 39 ? -17.345 70.363 -15.965 0.43 35.67 ? 39 GLU B CG 1 ATOM 2959 C CG B GLU B 2 39 ? -16.399 71.404 -16.494 0.57 34.00 ? 39 GLU B CG 1 ATOM 2960 C CD A GLU B 2 39 ? -18.220 69.170 -15.678 0.43 39.97 ? 39 GLU B CD 1 ATOM 2961 C CD B GLU B 2 39 ? -16.961 72.338 -15.381 0.57 47.68 ? 39 GLU B CD 1 ATOM 2962 O OE1 A GLU B 2 39 ? -18.004 68.480 -14.659 0.43 44.42 ? 39 GLU B OE1 1 ATOM 2963 O OE1 B GLU B 2 39 ? -16.998 71.951 -14.182 0.57 44.76 ? 39 GLU B OE1 1 ATOM 2964 O OE2 A GLU B 2 39 ? -19.148 68.929 -16.473 0.43 45.33 ? 39 GLU B OE2 1 ATOM 2965 O OE2 B GLU B 2 39 ? -17.370 73.467 -15.712 0.57 45.88 ? 39 GLU B OE2 1 ATOM 2966 N N . SER B 2 40 ? -13.165 69.685 -17.170 1.00 21.95 ? 40 SER B N 1 ATOM 2967 C CA . SER B 2 40 ? -11.995 70.221 -17.865 1.00 22.18 ? 40 SER B CA 1 ATOM 2968 C C . SER B 2 40 ? -11.542 69.268 -18.985 1.00 22.01 ? 40 SER B C 1 ATOM 2969 O O . SER B 2 40 ? -11.116 69.709 -20.039 1.00 20.35 ? 40 SER B O 1 ATOM 2970 C CB . SER B 2 40 ? -10.784 70.517 -16.930 1.00 25.45 ? 40 SER B CB 1 ATOM 2971 O OG . SER B 2 40 ? -10.395 69.316 -16.243 1.00 27.36 ? 40 SER B OG 1 ATOM 2972 N N . THR B 2 41 ? -11.659 67.981 -18.737 1.00 21.05 ? 41 THR B N 1 ATOM 2973 C CA . THR B 2 41 ? -11.380 67.018 -19.803 1.00 18.75 ? 41 THR B CA 1 ATOM 2974 C C . THR B 2 41 ? -12.280 67.227 -21.030 1.00 19.03 ? 41 THR B C 1 ATOM 2975 O O . THR B 2 41 ? -11.769 67.308 -22.189 1.00 19.48 ? 41 THR B O 1 ATOM 2976 C CB . THR B 2 41 ? -11.427 65.549 -19.336 1.00 16.15 ? 41 THR B CB 1 ATOM 2977 O OG1 . THR B 2 41 ? -10.391 65.336 -18.388 1.00 18.59 ? 41 THR B OG1 1 ATOM 2978 C CG2 . THR B 2 41 ? -11.148 64.600 -20.509 1.00 16.69 ? 41 THR B CG2 1 ATOM 2979 N N . GLN B 2 42 ? -13.579 67.307 -20.807 1.00 18.14 ? 42 GLN B N 1 ATOM 2980 C CA . GLN B 2 42 ? -14.494 67.489 -21.926 1.00 18.55 ? 42 GLN B CA 1 ATOM 2981 C C . GLN B 2 42 ? -14.248 68.828 -22.651 1.00 19.53 ? 42 GLN B C 1 ATOM 2982 O O . GLN B 2 42 ? -14.284 68.940 -23.880 1.00 18.60 ? 42 GLN B O 1 ATOM 2983 C CB . GLN B 2 42 ? -15.959 67.384 -21.459 1.00 19.79 ? 42 GLN B CB 1 ATOM 2984 C CG . GLN B 2 42 ? -16.974 67.492 -22.641 1.00 20.40 ? 42 GLN B CG 1 ATOM 2985 C CD . GLN B 2 42 ? -16.969 66.184 -23.463 1.00 21.46 ? 42 GLN B CD 1 ATOM 2986 O OE1 . GLN B 2 42 ? -17.223 65.132 -22.908 1.00 21.79 ? 42 GLN B OE1 1 ATOM 2987 N NE2 . GLN B 2 42 ? -16.627 66.263 -24.749 1.00 20.91 ? 42 GLN B NE2 1 ATOM 2988 N N . LYS B 2 43 ? -14.025 69.893 -21.861 1.00 19.31 ? 43 LYS B N 1 ATOM 2989 C CA . LYS B 2 43 ? -13.746 71.175 -22.503 1.00 22.76 ? 43 LYS B CA 1 ATOM 2990 C C . LYS B 2 43 ? -12.546 71.111 -23.411 1.00 20.30 ? 43 LYS B C 1 ATOM 2991 O O . LYS B 2 43 ? -12.546 71.685 -24.537 1.00 20.61 ? 43 LYS B O 1 ATOM 2992 C CB . LYS B 2 43 ? -13.494 72.196 -21.353 1.00 24.64 ? 43 LYS B CB 1 ATOM 2993 C CG . LYS B 2 43 ? -12.937 73.538 -21.849 1.00 36.90 ? 43 LYS B CG 1 ATOM 2994 C CD . LYS B 2 43 ? -12.217 74.292 -20.695 1.00 51.93 ? 43 LYS B CD 1 ATOM 2995 C CE . LYS B 2 43 ? -10.841 74.843 -21.166 1.00 52.13 ? 43 LYS B CE 1 ATOM 2996 N NZ . LYS B 2 43 ? -11.101 76.135 -21.953 1.00 38.45 ? 43 LYS B NZ 1 ATOM 2997 N N . ALA B 2 44 ? -11.496 70.430 -22.959 1.00 19.12 ? 44 ALA B N 1 ATOM 2998 C CA . ALA B 2 44 ? -10.310 70.321 -23.750 1.00 18.84 ? 44 ALA B CA 1 ATOM 2999 C C . ALA B 2 44 ? -10.501 69.442 -24.979 1.00 22.93 ? 44 ALA B C 1 ATOM 3000 O O . ALA B 2 44 ? -10.027 69.743 -26.047 1.00 17.77 ? 44 ALA B O 1 ATOM 3001 C CB . ALA B 2 44 ? -9.136 69.727 -22.865 1.00 19.47 ? 44 ALA B CB 1 ATOM 3002 N N . ILE B 2 45 ? -11.238 68.361 -24.821 1.00 18.39 ? 45 ILE B N 1 ATOM 3003 C CA . ILE B 2 45 ? -11.549 67.506 -25.979 1.00 15.67 ? 45 ILE B CA 1 ATOM 3004 C C . ILE B 2 45 ? -12.329 68.333 -27.030 1.00 16.79 ? 45 ILE B C 1 ATOM 3005 O O . ILE B 2 45 ? -12.078 68.214 -28.236 1.00 19.70 ? 45 ILE B O 1 ATOM 3006 C CB . ILE B 2 45 ? -12.383 66.297 -25.505 1.00 20.52 ? 45 ILE B CB 1 ATOM 3007 C CG1 . ILE B 2 45 ? -11.465 65.293 -24.810 1.00 18.24 ? 45 ILE B CG1 1 ATOM 3008 C CG2 . ILE B 2 45 ? -12.980 65.559 -26.725 1.00 21.53 ? 45 ILE B CG2 1 ATOM 3009 C CD1 . ILE B 2 45 ? -12.254 64.224 -23.972 1.00 18.50 ? 45 ILE B CD1 1 ATOM 3010 N N . ASP B 2 46 ? -13.280 69.112 -26.565 1.00 17.47 ? 46 ASP B N 1 ATOM 3011 C CA . ASP B 2 46 ? -14.119 69.902 -27.485 1.00 20.57 ? 46 ASP B CA 1 ATOM 3012 C C . ASP B 2 46 ? -13.209 70.880 -28.242 1.00 23.00 ? 46 ASP B C 1 ATOM 3013 O O . ASP B 2 46 ? -13.356 71.107 -29.461 1.00 17.76 ? 46 ASP B O 1 ATOM 3014 C CB . ASP B 2 46 ? -15.194 70.701 -26.724 1.00 18.33 ? 46 ASP B CB 1 ATOM 3015 C CG . ASP B 2 46 ? -16.318 69.801 -26.181 1.00 26.08 ? 46 ASP B CG 1 ATOM 3016 O OD1 . ASP B 2 46 ? -16.348 68.591 -26.493 1.00 23.20 ? 46 ASP B OD1 1 ATOM 3017 O OD2 . ASP B 2 46 ? -17.185 70.301 -25.450 1.00 26.13 ? 46 ASP B OD2 1 ATOM 3018 N N . GLY B 2 47 ? -12.255 71.444 -27.507 1.00 21.72 ? 47 GLY B N 1 ATOM 3019 C CA . GLY B 2 47 ? -11.373 72.440 -28.150 1.00 17.47 ? 47 GLY B CA 1 ATOM 3020 C C . GLY B 2 47 ? -10.484 71.789 -29.205 1.00 19.61 ? 47 GLY B C 1 ATOM 3021 O O . GLY B 2 47 ? -10.295 72.307 -30.337 1.00 17.14 ? 47 GLY B O 1 ATOM 3022 N N . VAL B 2 48 ? -9.933 70.620 -28.871 1.00 17.58 ? 48 VAL B N 1 ATOM 3023 C CA . VAL B 2 48 ? -9.040 69.949 -29.802 1.00 18.33 ? 48 VAL B CA 1 ATOM 3024 C C . VAL B 2 48 ? -9.858 69.443 -31.019 1.00 19.20 ? 48 VAL B C 1 ATOM 3025 O O . VAL B 2 48 ? -9.375 69.463 -32.131 1.00 18.39 ? 48 VAL B O 1 ATOM 3026 C CB . VAL B 2 48 ? -8.346 68.765 -29.100 1.00 20.11 ? 48 VAL B CB 1 ATOM 3027 C CG1 . VAL B 2 48 ? -7.582 67.835 -30.089 1.00 20.27 ? 48 VAL B CG1 1 ATOM 3028 C CG2 . VAL B 2 48 ? -7.365 69.297 -28.041 1.00 18.79 ? 48 VAL B CG2 1 ATOM 3029 N N . THR B 2 49 ? -11.070 68.947 -30.763 1.00 17.96 ? 49 THR B N 1 ATOM 3030 C CA . THR B 2 49 ? -11.939 68.504 -31.848 1.00 17.25 ? 49 THR B CA 1 ATOM 3031 C C . THR B 2 49 ? -12.181 69.660 -32.810 1.00 21.82 ? 49 THR B C 1 ATOM 3032 O O . THR B 2 49 ? -12.084 69.484 -34.036 1.00 22.07 ? 49 THR B O 1 ATOM 3033 C CB . THR B 2 49 ? -13.291 68.030 -31.312 1.00 18.29 ? 49 THR B CB 1 ATOM 3034 O OG1 . THR B 2 49 ? -13.052 66.885 -30.431 1.00 19.13 ? 49 THR B OG1 1 ATOM 3035 C CG2 . THR B 2 49 ? -14.215 67.616 -32.509 1.00 19.98 ? 49 THR B CG2 1 ATOM 3036 N N . ASN B 2 50 ? -12.482 70.823 -32.260 1.00 17.70 ? 50 ASN B N 1 ATOM 3037 C CA . ASN B 2 50 ? -12.728 71.986 -33.129 1.00 20.28 ? 50 ASN B CA 1 ATOM 3038 C C . ASN B 2 50 ? -11.478 72.392 -33.890 1.00 24.13 ? 50 ASN B C 1 ATOM 3039 O O . ASN B 2 50 ? -11.547 72.870 -35.040 1.00 22.44 ? 50 ASN B O 1 ATOM 3040 C CB . ASN B 2 50 ? -13.201 73.194 -32.300 1.00 19.65 ? 50 ASN B CB 1 ATOM 3041 C CG . ASN B 2 50 ? -14.677 73.215 -32.079 1.00 30.31 ? 50 ASN B CG 1 ATOM 3042 O OD1 . ASN B 2 50 ? -15.154 73.082 -30.959 1.00 32.42 ? 50 ASN B OD1 1 ATOM 3043 N ND2 . ASN B 2 50 ? -15.419 73.377 -33.148 1.00 37.89 ? 50 ASN B ND2 1 ATOM 3044 N N . LYS B 2 51 ? -10.347 72.327 -33.203 1.00 19.99 ? 51 LYS B N 1 ATOM 3045 C CA . LYS B 2 51 ? -9.058 72.683 -33.804 1.00 21.74 ? 51 LYS B CA 1 ATOM 3046 C C . LYS B 2 51 ? -8.816 71.826 -35.019 1.00 23.65 ? 51 LYS B C 1 ATOM 3047 O O . LYS B 2 51 ? -8.514 72.307 -36.125 1.00 22.82 ? 51 LYS B O 1 ATOM 3048 C CB . LYS B 2 51 ? -7.894 72.525 -32.786 1.00 19.94 ? 51 LYS B CB 1 ATOM 3049 C CG . LYS B 2 51 ? -6.529 72.741 -33.430 1.00 19.69 ? 51 LYS B CG 1 ATOM 3050 C CD . LYS B 2 51 ? -5.396 72.562 -32.402 1.00 19.90 ? 51 LYS B CD 1 ATOM 3051 C CE . LYS B 2 51 ? -5.569 73.646 -31.292 1.00 21.10 ? 51 LYS B CE 1 ATOM 3052 N NZ . LYS B 2 51 ? -4.164 74.027 -30.787 1.00 19.77 ? 51 LYS B NZ 1 ATOM 3053 N N . VAL B 2 52 ? -9.016 70.511 -34.862 1.00 22.21 ? 52 VAL B N 1 ATOM 3054 C CA . VAL B 2 52 ? -8.751 69.630 -35.981 1.00 22.58 ? 52 VAL B CA 1 ATOM 3055 C C . VAL B 2 52 ? -9.680 70.012 -37.134 1.00 24.58 ? 52 VAL B C 1 ATOM 3056 O O . VAL B 2 52 ? -9.220 70.151 -38.301 1.00 26.65 ? 52 VAL B O 1 ATOM 3057 C CB . VAL B 2 52 ? -8.900 68.139 -35.565 1.00 24.33 ? 52 VAL B CB 1 ATOM 3058 C CG1 . VAL B 2 52 ? -8.842 67.229 -36.792 1.00 31.47 ? 52 VAL B CG1 1 ATOM 3059 C CG2 . VAL B 2 52 ? -7.769 67.744 -34.635 1.00 25.17 ? 52 VAL B CG2 1 ATOM 3060 N N A ASN B 2 53 ? -10.950 70.232 -36.813 0.49 25.46 ? 53 ASN B N 1 ATOM 3061 N N B ASN B 2 53 ? -10.961 70.215 -36.828 0.51 25.46 ? 53 ASN B N 1 ATOM 3062 C CA A ASN B 2 53 ? -11.955 70.569 -37.829 0.49 28.66 ? 53 ASN B CA 1 ATOM 3063 C CA B ASN B 2 53 ? -11.930 70.584 -37.870 0.51 28.65 ? 53 ASN B CA 1 ATOM 3064 C C A ASN B 2 53 ? -11.761 71.943 -38.499 0.49 31.18 ? 53 ASN B C 1 ATOM 3065 C C B ASN B 2 53 ? -11.580 71.897 -38.559 0.51 31.22 ? 53 ASN B C 1 ATOM 3066 O O A ASN B 2 53 ? -12.075 72.111 -39.681 0.49 31.66 ? 53 ASN B O 1 ATOM 3067 O O B ASN B 2 53 ? -11.657 71.996 -39.797 0.51 31.69 ? 53 ASN B O 1 ATOM 3068 C CB A ASN B 2 53 ? -13.360 70.381 -37.267 0.49 32.46 ? 53 ASN B CB 1 ATOM 3069 C CB B ASN B 2 53 ? -13.349 70.692 -37.336 0.51 32.37 ? 53 ASN B CB 1 ATOM 3070 C CG A ASN B 2 53 ? -13.770 68.904 -37.241 0.49 29.88 ? 53 ASN B CG 1 ATOM 3071 C CG B ASN B 2 53 ? -14.379 70.688 -38.456 0.51 33.71 ? 53 ASN B CG 1 ATOM 3072 O OD1 A ASN B 2 53 ? -13.282 68.108 -38.066 0.49 37.66 ? 53 ASN B OD1 1 ATOM 3073 O OD1 B ASN B 2 53 ? -14.284 69.890 -39.403 0.51 35.65 ? 53 ASN B OD1 1 ATOM 3074 N ND2 A ASN B 2 53 ? -14.667 68.529 -36.321 0.49 35.00 ? 53 ASN B ND2 1 ATOM 3075 N ND2 B ASN B 2 53 ? -15.333 71.601 -38.382 0.51 42.42 ? 53 ASN B ND2 1 ATOM 3076 N N . SER B 2 54 ? -11.199 72.894 -37.752 1.00 25.68 ? 54 SER B N 1 ATOM 3077 C CA . SER B 2 54 ? -10.837 74.217 -38.290 1.00 22.04 ? 54 SER B CA 1 ATOM 3078 C C . SER B 2 54 ? -9.722 74.104 -39.312 1.00 26.88 ? 54 SER B C 1 ATOM 3079 O O . SER B 2 54 ? -9.745 74.753 -40.347 1.00 29.85 ? 54 SER B O 1 ATOM 3080 C CB . SER B 2 54 ? -10.381 75.162 -37.174 1.00 29.38 ? 54 SER B CB 1 ATOM 3081 O OG . SER B 2 54 ? -11.509 75.441 -36.369 1.00 29.09 ? 54 SER B OG 1 ATOM 3082 N N . ILE B 2 55 ? -8.709 73.305 -38.980 1.00 24.36 ? 55 ILE B N 1 ATOM 3083 C CA . ILE B 2 55 ? -7.520 73.165 -39.793 1.00 28.43 ? 55 ILE B CA 1 ATOM 3084 C C . ILE B 2 55 ? -7.941 72.561 -41.121 1.00 30.07 ? 55 ILE B C 1 ATOM 3085 O O . ILE B 2 55 ? -7.590 73.053 -42.184 1.00 31.77 ? 55 ILE B O 1 ATOM 3086 C CB . ILE B 2 55 ? -6.459 72.270 -39.075 1.00 27.00 ? 55 ILE B CB 1 ATOM 3087 C CG1 . ILE B 2 55 ? -5.843 73.063 -37.942 1.00 27.86 ? 55 ILE B CG1 1 ATOM 3088 C CG2 . ILE B 2 55 ? -5.333 71.820 -40.044 1.00 31.85 ? 55 ILE B CG2 1 ATOM 3089 C CD1 . ILE B 2 55 ? -4.903 72.200 -37.041 1.00 30.43 ? 55 ILE B CD1 1 ATOM 3090 N N . ILE B 2 56 ? -8.728 71.499 -41.060 1.00 29.46 ? 56 ILE B N 1 ATOM 3091 C CA . ILE B 2 56 ? -9.183 70.828 -42.283 1.00 34.07 ? 56 ILE B CA 1 ATOM 3092 C C . ILE B 2 56 ? -10.142 71.691 -43.113 1.00 29.33 ? 56 ILE B C 1 ATOM 3093 O O . ILE B 2 56 ? -10.032 71.721 -44.361 1.00 35.46 ? 56 ILE B O 1 ATOM 3094 C CB . ILE B 2 56 ? -9.934 69.478 -41.940 1.00 34.50 ? 56 ILE B CB 1 ATOM 3095 C CG1 . ILE B 2 56 ? -9.029 68.458 -41.258 1.00 35.30 ? 56 ILE B CG1 1 ATOM 3096 C CG2 . ILE B 2 56 ? -10.593 68.825 -43.215 1.00 32.05 ? 56 ILE B CG2 1 ATOM 3097 C CD1 . ILE B 2 56 ? -7.567 68.683 -41.403 1.00 43.64 ? 56 ILE B CD1 1 ATOM 3098 N N . ASP B 2 57 ? -11.087 72.368 -42.462 1.00 29.17 ? 57 ASP B N 1 ATOM 3099 C CA A ASP B 2 57 ? -12.060 73.229 -43.150 0.50 30.21 ? 57 ASP B CA 1 ATOM 3100 C CA B ASP B 2 57 ? -12.044 73.175 -43.206 0.50 30.23 ? 57 ASP B CA 1 ATOM 3101 C C . ASP B 2 57 ? -11.331 74.331 -43.930 1.00 33.85 ? 57 ASP B C 1 ATOM 3102 O O . ASP B 2 57 ? -11.692 74.651 -45.071 1.00 33.51 ? 57 ASP B O 1 ATOM 3103 C CB A ASP B 2 57 ? -13.026 73.854 -42.132 0.50 32.73 ? 57 ASP B CB 1 ATOM 3104 C CB B ASP B 2 57 ? -13.184 73.665 -42.311 0.50 32.76 ? 57 ASP B CB 1 ATOM 3105 C CG A ASP B 2 57 ? -14.035 74.814 -42.762 0.50 38.23 ? 57 ASP B CG 1 ATOM 3106 C CG B ASP B 2 57 ? -14.204 72.570 -42.004 0.50 32.27 ? 57 ASP B CG 1 ATOM 3107 O OD1 A ASP B 2 57 ? -14.744 74.420 -43.716 0.50 40.77 ? 57 ASP B OD1 1 ATOM 3108 O OD1 B ASP B 2 57 ? -14.350 71.616 -42.809 0.50 42.69 ? 57 ASP B OD1 1 ATOM 3109 O OD2 A ASP B 2 57 ? -14.120 75.966 -42.292 0.50 43.05 ? 57 ASP B OD2 1 ATOM 3110 O OD2 B ASP B 2 57 ? -14.870 72.647 -40.957 0.50 39.78 ? 57 ASP B OD2 1 ATOM 3111 N N . LYS B 2 58 ? -10.320 74.951 -43.299 1.00 33.28 ? 58 LYS B N 1 ATOM 3112 C CA . LYS B 2 58 ? -9.652 76.095 -43.961 1.00 31.70 ? 58 LYS B CA 1 ATOM 3113 C C . LYS B 2 58 ? -8.819 75.628 -45.159 1.00 37.48 ? 58 LYS B C 1 ATOM 3114 O O . LYS B 2 58 ? -8.539 76.418 -46.056 1.00 34.90 ? 58 LYS B O 1 ATOM 3115 C CB . LYS B 2 58 ? -8.796 76.943 -42.988 1.00 37.33 ? 58 LYS B CB 1 ATOM 3116 C CG . LYS B 2 58 ? -9.599 77.663 -41.908 1.00 36.07 ? 58 LYS B CG 1 ATOM 3117 C CD . LYS B 2 58 ? -10.775 78.406 -42.556 1.00 42.52 ? 58 LYS B CD 1 ATOM 3118 C CE . LYS B 2 58 ? -11.600 79.191 -41.583 1.00 34.82 ? 58 LYS B CE 1 ATOM 3119 N NZ . LYS B 2 58 ? -12.939 79.653 -42.074 1.00 30.90 ? 58 LYS B NZ 1 ATOM 3120 N N . MET B 2 59 ? -8.448 74.340 -45.188 1.00 41.12 ? 59 MET B N 1 ATOM 3121 C CA . MET B 2 59 ? -7.654 73.760 -46.289 1.00 44.80 ? 59 MET B CA 1 ATOM 3122 C C . MET B 2 59 ? -8.575 73.123 -47.331 1.00 46.07 ? 59 MET B C 1 ATOM 3123 O O . MET B 2 59 ? -8.123 72.534 -48.315 1.00 42.75 ? 59 MET B O 1 ATOM 3124 C CB . MET B 2 59 ? -6.688 72.685 -45.745 1.00 40.46 ? 59 MET B CB 1 ATOM 3125 C CG . MET B 2 59 ? -5.703 73.180 -44.709 1.00 46.20 ? 59 MET B CG 1 ATOM 3126 S SD . MET B 2 59 ? -4.323 73.957 -45.530 1.00 45.45 ? 59 MET B SD 1 ATOM 3127 C CE . MET B 2 59 ? -3.312 74.426 -44.180 1.00 33.78 ? 59 MET B CE 1 ATOM 3128 N N . ASN B 2 60 ? -9.883 73.256 -47.127 1.00 45.01 ? 60 ASN B N 1 ATOM 3129 C CA . ASN B 2 60 ? -10.850 72.598 -47.993 1.00 44.15 ? 60 ASN B CA 1 ATOM 3130 C C . ASN B 2 60 ? -10.819 73.113 -49.441 1.00 57.18 ? 60 ASN B C 1 ATOM 3131 O O . ASN B 2 60 ? -11.079 72.360 -50.384 1.00 45.96 ? 60 ASN B O 1 ATOM 3132 C CB . ASN B 2 60 ? -12.257 72.767 -47.420 1.00 50.12 ? 60 ASN B CB 1 ATOM 3133 C CG . ASN B 2 60 ? -13.271 71.894 -48.109 1.00 75.70 ? 60 ASN B CG 1 ATOM 3134 O OD1 . ASN B 2 60 ? -12.973 70.753 -48.483 1.00 85.85 ? 60 ASN B OD1 1 ATOM 3135 N ND2 . ASN B 2 60 ? -14.483 72.418 -48.284 1.00 79.89 ? 60 ASN B ND2 1 ATOM 3136 N N . THR B 2 61 ? -10.527 74.396 -49.628 1.00 48.81 ? 61 THR B N 1 ATOM 3137 C CA . THR B 2 61 ? -10.367 74.899 -50.999 1.00 47.90 ? 61 THR B CA 1 ATOM 3138 C C . THR B 2 61 ? -8.938 75.327 -51.196 1.00 56.81 ? 61 THR B C 1 ATOM 3139 O O . THR B 2 61 ? -8.571 76.477 -50.927 1.00 55.52 ? 61 THR B O 1 ATOM 3140 C CB . THR B 2 61 ? -11.207 76.143 -51.353 1.00 49.25 ? 61 THR B CB 1 ATOM 3141 O OG1 . THR B 2 61 ? -12.580 75.935 -51.035 1.00 57.77 ? 61 THR B OG1 1 ATOM 3142 C CG2 . THR B 2 61 ? -11.069 76.435 -52.866 1.00 52.21 ? 61 THR B CG2 1 ATOM 3143 N N . GLN B 2 62 ? -8.143 74.414 -51.701 1.00 48.75 ? 62 GLN B N 1 ATOM 3144 C CA . GLN B 2 62 ? -6.773 74.744 -52.013 1.00 46.78 ? 62 GLN B CA 1 ATOM 3145 C C . GLN B 2 62 ? -6.489 74.322 -53.465 1.00 49.65 ? 62 GLN B C 1 ATOM 3146 O O . GLN B 2 62 ? -7.388 73.866 -54.188 1.00 49.83 ? 62 GLN B O 1 ATOM 3147 C CB . GLN B 2 62 ? -5.829 74.134 -50.971 1.00 41.64 ? 62 GLN B CB 1 ATOM 3148 C CG . GLN B 2 62 ? -5.396 72.752 -51.216 1.00 43.68 ? 62 GLN B CG 1 ATOM 3149 C CD . GLN B 2 62 ? -4.324 72.295 -50.251 1.00 58.01 ? 62 GLN B CD 1 ATOM 3150 O OE1 . GLN B 2 62 ? -3.358 71.596 -50.632 1.00 53.41 ? 62 GLN B OE1 1 ATOM 3151 N NE2 . GLN B 2 62 ? -4.490 72.662 -48.984 1.00 54.54 ? 62 GLN B NE2 1 ATOM 3152 N N . PHE B 2 63 ? -5.258 74.482 -53.907 1.00 38.62 ? 63 PHE B N 1 ATOM 3153 C CA . PHE B 2 63 ? -5.006 74.478 -55.350 1.00 35.85 ? 63 PHE B CA 1 ATOM 3154 C C . PHE B 2 63 ? -5.011 73.051 -55.894 1.00 38.46 ? 63 PHE B C 1 ATOM 3155 O O . PHE B 2 63 ? -4.393 72.165 -55.284 1.00 35.48 ? 63 PHE B O 1 ATOM 3156 C CB . PHE B 2 63 ? -3.663 75.094 -55.618 1.00 30.72 ? 63 PHE B CB 1 ATOM 3157 C CG . PHE B 2 63 ? -3.347 75.194 -57.078 1.00 32.17 ? 63 PHE B CG 1 ATOM 3158 C CD1 . PHE B 2 63 ? -3.846 76.239 -57.827 1.00 30.04 ? 63 PHE B CD1 1 ATOM 3159 C CD2 . PHE B 2 63 ? -2.580 74.216 -57.702 1.00 35.80 ? 63 PHE B CD2 1 ATOM 3160 C CE1 . PHE B 2 63 ? -3.603 76.315 -59.185 1.00 34.84 ? 63 PHE B CE1 1 ATOM 3161 C CE2 . PHE B 2 63 ? -2.312 74.298 -59.056 1.00 34.09 ? 63 PHE B CE2 1 ATOM 3162 C CZ . PHE B 2 63 ? -2.822 75.335 -59.807 1.00 30.23 ? 63 PHE B CZ 1 ATOM 3163 N N . GLU B 2 64 ? -5.690 72.874 -57.024 1.00 31.21 ? 64 GLU B N 1 ATOM 3164 C CA . GLU B 2 64 ? -5.722 71.611 -57.795 1.00 31.96 ? 64 GLU B CA 1 ATOM 3165 C C . GLU B 2 64 ? -5.045 71.714 -59.154 1.00 32.56 ? 64 GLU B C 1 ATOM 3166 O O . GLU B 2 64 ? -5.530 72.380 -60.106 1.00 36.82 ? 64 GLU B O 1 ATOM 3167 C CB . GLU B 2 64 ? -7.176 71.141 -57.993 1.00 36.46 ? 64 GLU B CB 1 ATOM 3168 C CG . GLU B 2 64 ? -7.890 70.842 -56.685 1.00 44.58 ? 64 GLU B CG 1 ATOM 3169 C CD . GLU B 2 64 ? -9.399 70.636 -56.854 1.00 60.10 ? 64 GLU B CD 1 ATOM 3170 O OE1 . GLU B 2 64 ? -9.966 71.066 -57.889 1.00 66.21 ? 64 GLU B OE1 1 ATOM 3171 O OE2 . GLU B 2 64 ? -10.016 70.050 -55.941 1.00 65.49 ? 64 GLU B OE2 1 ATOM 3172 N N . ALA B 2 65 ? -3.922 71.018 -59.239 1.00 29.07 ? 65 ALA B N 1 ATOM 3173 C CA . ALA B 2 65 ? -3.160 70.940 -60.472 1.00 30.33 ? 65 ALA B CA 1 ATOM 3174 C C . ALA B 2 65 ? -3.939 70.187 -61.517 1.00 37.25 ? 65 ALA B C 1 ATOM 3175 O O . ALA B 2 65 ? -4.716 69.259 -61.185 1.00 27.10 ? 65 ALA B O 1 ATOM 3176 C CB . ALA B 2 65 ? -1.799 70.319 -60.217 1.00 31.97 ? 65 ALA B CB 1 ATOM 3177 N N . VAL B 2 66 ? -3.758 70.599 -62.777 1.00 32.89 ? 66 VAL B N 1 ATOM 3178 C CA . VAL B 2 66 ? -4.495 70.048 -63.927 1.00 35.30 ? 66 VAL B CA 1 ATOM 3179 C C . VAL B 2 66 ? -3.500 69.805 -65.062 1.00 41.76 ? 66 VAL B C 1 ATOM 3180 O O . VAL B 2 66 ? -2.680 70.667 -65.336 1.00 39.85 ? 66 VAL B O 1 ATOM 3181 C CB . VAL B 2 66 ? -5.534 71.088 -64.453 1.00 46.19 ? 66 VAL B CB 1 ATOM 3182 C CG1 . VAL B 2 66 ? -6.309 70.542 -65.662 1.00 51.57 ? 66 VAL B CG1 1 ATOM 3183 C CG2 . VAL B 2 66 ? -6.495 71.533 -63.341 1.00 52.48 ? 66 VAL B CG2 1 ATOM 3184 N N . GLY B 2 67 ? -3.559 68.666 -65.747 1.00 32.64 ? 67 GLY B N 1 ATOM 3185 C CA . GLY B 2 67 ? -2.596 68.451 -66.824 1.00 38.30 ? 67 GLY B CA 1 ATOM 3186 C C . GLY B 2 67 ? -2.936 69.399 -67.994 1.00 35.37 ? 67 GLY B C 1 ATOM 3187 O O . GLY B 2 67 ? -4.106 69.574 -68.315 1.00 36.28 ? 67 GLY B O 1 ATOM 3188 N N . ARG B 2 68 ? -1.920 70.047 -68.578 1.00 35.27 ? 68 ARG B N 1 ATOM 3189 C CA . ARG B 2 68 ? -2.096 70.907 -69.767 1.00 34.15 ? 68 ARG B CA 1 ATOM 3190 C C . ARG B 2 68 ? -0.921 70.588 -70.646 1.00 33.09 ? 68 ARG B C 1 ATOM 3191 O O . ARG B 2 68 ? 0.156 70.419 -70.127 1.00 39.68 ? 68 ARG B O 1 ATOM 3192 C CB . ARG B 2 68 ? -2.033 72.427 -69.448 1.00 35.39 ? 68 ARG B CB 1 ATOM 3193 C CG . ARG B 2 68 ? -3.152 72.949 -68.633 1.00 32.51 ? 68 ARG B CG 1 ATOM 3194 C CD . ARG B 2 68 ? -3.057 74.475 -68.350 1.00 30.07 ? 68 ARG B CD 1 ATOM 3195 N NE . ARG B 2 68 ? -4.085 74.790 -67.393 1.00 29.97 ? 68 ARG B NE 1 ATOM 3196 C CZ . ARG B 2 68 ? -3.895 74.723 -66.085 1.00 34.60 ? 68 ARG B CZ 1 ATOM 3197 N NH1 . ARG B 2 68 ? -2.675 74.485 -65.559 1.00 30.66 ? 68 ARG B NH1 1 ATOM 3198 N NH2 . ARG B 2 68 ? -4.923 74.962 -65.284 1.00 36.13 ? 68 ARG B NH2 1 ATOM 3199 N N . GLU B 2 69 ? -1.114 70.502 -71.971 1.00 22.57 ? 69 GLU B N 1 ATOM 3200 C CA . GLU B 2 69 ? 0.005 70.164 -72.850 1.00 22.02 ? 69 GLU B CA 1 ATOM 3201 C C . GLU B 2 69 ? 0.361 71.269 -73.830 1.00 20.48 ? 69 GLU B C 1 ATOM 3202 O O . GLU B 2 69 ? -0.518 72.026 -74.280 1.00 19.42 ? 69 GLU B O 1 ATOM 3203 C CB . GLU B 2 69 ? -0.316 68.953 -73.674 1.00 26.71 ? 69 GLU B CB 1 ATOM 3204 C CG . GLU B 2 69 ? -0.389 67.723 -72.775 1.00 38.88 ? 69 GLU B CG 1 ATOM 3205 C CD . GLU B 2 69 ? -0.887 66.526 -73.524 1.00 46.65 ? 69 GLU B CD 1 ATOM 3206 O OE1 . GLU B 2 69 ? -0.049 65.951 -74.225 1.00 41.97 ? 69 GLU B OE1 1 ATOM 3207 O OE2 . GLU B 2 69 ? -2.099 66.179 -73.394 1.00 55.46 ? 69 GLU B OE2 1 ATOM 3208 N N . PHE B 2 70 ? 1.627 71.258 -74.233 1.00 20.86 ? 70 PHE B N 1 ATOM 3209 C CA . PHE B 2 70 ? 2.138 72.383 -75.055 1.00 20.31 ? 70 PHE B CA 1 ATOM 3210 C C . PHE B 2 70 ? 3.091 71.794 -76.085 1.00 22.56 ? 70 PHE B C 1 ATOM 3211 O O . PHE B 2 70 ? 3.821 70.825 -75.793 1.00 25.70 ? 70 PHE B O 1 ATOM 3212 C CB . PHE B 2 70 ? 2.939 73.329 -74.156 1.00 20.03 ? 70 PHE B CB 1 ATOM 3213 C CG . PHE B 2 70 ? 2.105 73.944 -73.073 1.00 19.04 ? 70 PHE B CG 1 ATOM 3214 C CD1 . PHE B 2 70 ? 2.085 73.365 -71.812 1.00 22.29 ? 70 PHE B CD1 1 ATOM 3215 C CD2 . PHE B 2 70 ? 1.253 75.007 -73.364 1.00 20.66 ? 70 PHE B CD2 1 ATOM 3216 C CE1 . PHE B 2 70 ? 1.227 73.916 -70.804 1.00 22.80 ? 70 PHE B CE1 1 ATOM 3217 C CE2 . PHE B 2 70 ? 0.461 75.579 -72.349 1.00 22.94 ? 70 PHE B CE2 1 ATOM 3218 C CZ . PHE B 2 70 ? 0.438 75.003 -71.100 1.00 23.38 ? 70 PHE B CZ 1 ATOM 3219 N N . ASN B 2 71 ? 3.131 72.413 -77.247 1.00 21.19 ? 71 ASN B N 1 ATOM 3220 C CA . ASN B 2 71 ? 4.039 71.902 -78.256 1.00 23.72 ? 71 ASN B CA 1 ATOM 3221 C C . ASN B 2 71 ? 5.438 72.478 -78.148 1.00 24.96 ? 71 ASN B C 1 ATOM 3222 O O . ASN B 2 71 ? 5.761 73.227 -77.238 1.00 24.37 ? 71 ASN B O 1 ATOM 3223 C CB . ASN B 2 71 ? 3.473 72.079 -79.648 1.00 24.89 ? 71 ASN B CB 1 ATOM 3224 C CG . ASN B 2 71 ? 3.425 73.546 -80.131 1.00 26.95 ? 71 ASN B CG 1 ATOM 3225 O OD1 . ASN B 2 71 ? 4.311 74.380 -79.866 1.00 26.50 ? 71 ASN B OD1 1 ATOM 3226 N ND2 . ASN B 2 71 ? 2.381 73.858 -80.873 1.00 36.80 ? 71 ASN B ND2 1 ATOM 3227 N N . ASN B 2 72 ? 6.305 72.061 -79.082 1.00 24.43 ? 72 ASN B N 1 ATOM 3228 C CA . ASN B 2 72 ? 7.710 72.371 -78.946 1.00 25.00 ? 72 ASN B CA 1 ATOM 3229 C C . ASN B 2 72 ? 8.068 73.836 -79.174 1.00 24.33 ? 72 ASN B C 1 ATOM 3230 O O . ASN B 2 72 ? 9.170 74.264 -78.844 1.00 26.64 ? 72 ASN B O 1 ATOM 3231 C CB . ASN B 2 72 ? 8.497 71.506 -79.963 1.00 28.53 ? 72 ASN B CB 1 ATOM 3232 C CG . ASN B 2 72 ? 9.983 71.744 -79.872 1.00 36.88 ? 72 ASN B CG 1 ATOM 3233 O OD1 . ASN B 2 72 ? 10.603 71.476 -78.825 1.00 40.63 ? 72 ASN B OD1 1 ATOM 3234 N ND2 . ASN B 2 72 ? 10.572 72.302 -80.956 1.00 44.30 ? 72 ASN B ND2 1 ATOM 3235 N N . LEU B 2 73 ? 7.120 74.620 -79.664 1.00 21.13 ? 73 LEU B N 1 ATOM 3236 C CA . LEU B 2 73 ? 7.337 76.053 -79.832 1.00 21.71 ? 73 LEU B CA 1 ATOM 3237 C C . LEU B 2 73 ? 6.403 76.855 -78.904 1.00 22.22 ? 73 LEU B C 1 ATOM 3238 O O . LEU B 2 73 ? 6.102 78.024 -79.138 1.00 19.46 ? 73 LEU B O 1 ATOM 3239 C CB . LEU B 2 73 ? 7.160 76.480 -81.297 1.00 22.36 ? 73 LEU B CB 1 ATOM 3240 C CG . LEU B 2 73 ? 8.420 76.156 -82.117 1.00 31.64 ? 73 LEU B CG 1 ATOM 3241 C CD1 . LEU B 2 73 ? 8.096 76.434 -83.601 1.00 32.63 ? 73 LEU B CD1 1 ATOM 3242 C CD2 . LEU B 2 73 ? 9.553 77.082 -81.686 1.00 27.70 ? 73 LEU B CD2 1 ATOM 3243 N N . GLU B 2 74 ? 5.976 76.196 -77.817 1.00 20.08 ? 74 GLU B N 1 ATOM 3244 C CA . GLU B 2 74 ? 5.257 76.881 -76.723 1.00 16.87 ? 74 GLU B CA 1 ATOM 3245 C C . GLU B 2 74 ? 5.998 76.680 -75.395 1.00 20.13 ? 74 GLU B C 1 ATOM 3246 O O . GLU B 2 74 ? 5.366 76.500 -74.328 1.00 19.47 ? 74 GLU B O 1 ATOM 3247 C CB . GLU B 2 74 ? 3.818 76.231 -76.591 1.00 16.84 ? 74 GLU B CB 1 ATOM 3248 C CG . GLU B 2 74 ? 2.957 76.604 -77.815 1.00 18.95 ? 74 GLU B CG 1 ATOM 3249 C CD . GLU B 2 74 ? 1.555 75.934 -77.785 1.00 20.84 ? 74 GLU B CD 1 ATOM 3250 O OE1 . GLU B 2 74 ? 1.480 74.764 -77.416 1.00 21.75 ? 74 GLU B OE1 1 ATOM 3251 O OE2 . GLU B 2 74 ? 0.584 76.581 -78.184 1.00 21.09 ? 74 GLU B OE2 1 ATOM 3252 N N . ARG B 2 75 ? 7.338 76.662 -75.455 1.00 17.65 ? 75 ARG B N 1 ATOM 3253 C CA . ARG B 2 75 ? 8.097 76.400 -74.249 1.00 17.85 ? 75 ARG B CA 1 ATOM 3254 C C . ARG B 2 75 ? 7.942 77.504 -73.179 1.00 16.83 ? 75 ARG B C 1 ATOM 3255 O O . ARG B 2 75 ? 8.077 77.204 -71.976 1.00 17.84 ? 75 ARG B O 1 ATOM 3256 C CB . ARG B 2 75 ? 9.598 76.199 -74.515 1.00 20.00 ? 75 ARG B CB 1 ATOM 3257 C CG . ARG B 2 75 ? 9.901 75.023 -75.468 1.00 23.85 ? 75 ARG B CG 1 ATOM 3258 C CD . ARG B 2 75 ? 9.330 73.780 -74.865 1.00 31.58 ? 75 ARG B CD 1 ATOM 3259 N NE . ARG B 2 75 ? 9.327 72.590 -75.735 1.00 51.87 ? 75 ARG B NE 1 ATOM 3260 C CZ . ARG B 2 75 ? 10.330 71.717 -75.845 1.00 61.69 ? 75 ARG B CZ 1 ATOM 3261 N NH1 . ARG B 2 75 ? 11.461 71.910 -75.171 1.00 68.85 ? 75 ARG B NH1 1 ATOM 3262 N NH2 . ARG B 2 75 ? 10.206 70.661 -76.655 1.00 56.30 ? 75 ARG B NH2 1 ATOM 3263 N N . ARG B 2 76 ? 7.756 78.749 -73.605 1.00 18.46 ? 76 ARG B N 1 ATOM 3264 C CA . ARG B 2 76 ? 7.626 79.808 -72.619 1.00 15.85 ? 76 ARG B CA 1 ATOM 3265 C C . ARG B 2 76 ? 6.332 79.572 -71.812 1.00 18.03 ? 76 ARG B C 1 ATOM 3266 O O . ARG B 2 76 ? 6.372 79.678 -70.574 1.00 17.37 ? 76 ARG B O 1 ATOM 3267 C CB . ARG B 2 76 ? 7.566 81.190 -73.265 1.00 17.37 ? 76 ARG B CB 1 ATOM 3268 C CG . ARG B 2 76 ? 8.920 81.567 -73.876 1.00 16.16 ? 76 ARG B CG 1 ATOM 3269 C CD . ARG B 2 76 ? 8.738 82.853 -74.761 1.00 15.52 ? 76 ARG B CD 1 ATOM 3270 N NE . ARG B 2 76 ? 7.834 82.505 -75.876 1.00 19.14 ? 76 ARG B NE 1 ATOM 3271 C CZ . ARG B 2 76 ? 6.996 83.384 -76.425 1.00 16.41 ? 76 ARG B CZ 1 ATOM 3272 N NH1 . ARG B 2 76 ? 6.920 84.664 -75.959 1.00 18.10 ? 76 ARG B NH1 1 ATOM 3273 N NH2 . ARG B 2 76 ? 6.194 82.988 -77.392 1.00 17.76 ? 76 ARG B NH2 1 ATOM 3274 N N . ILE B 2 77 ? 5.213 79.329 -72.509 1.00 17.58 ? 77 ILE B N 1 ATOM 3275 C CA . ILE B 2 77 ? 3.967 79.161 -71.736 1.00 14.56 ? 77 ILE B CA 1 ATOM 3276 C C . ILE B 2 77 ? 3.948 77.835 -70.963 1.00 19.03 ? 77 ILE B C 1 ATOM 3277 O O . ILE B 2 77 ? 3.389 77.749 -69.872 1.00 19.56 ? 77 ILE B O 1 ATOM 3278 C CB . ILE B 2 77 ? 2.684 79.345 -72.576 1.00 17.39 ? 77 ILE B CB 1 ATOM 3279 C CG1 . ILE B 2 77 ? 2.605 78.358 -73.730 1.00 21.49 ? 77 ILE B CG1 1 ATOM 3280 C CG2 . ILE B 2 77 ? 2.578 80.819 -73.098 1.00 21.29 ? 77 ILE B CG2 1 ATOM 3281 C CD1 . ILE B 2 77 ? 1.226 78.484 -74.520 1.00 26.96 ? 77 ILE B CD1 1 ATOM 3282 N N . GLU B 2 78 ? 4.593 76.828 -71.499 1.00 18.02 ? 78 GLU B N 1 ATOM 3283 C CA . GLU B 2 78 ? 4.812 75.586 -70.745 1.00 17.22 ? 78 GLU B CA 1 ATOM 3284 C C . GLU B 2 78 ? 5.542 75.798 -69.466 1.00 19.14 ? 78 GLU B C 1 ATOM 3285 O O . GLU B 2 78 ? 5.140 75.289 -68.409 1.00 18.37 ? 78 GLU B O 1 ATOM 3286 C CB . GLU B 2 78 ? 5.561 74.571 -71.593 1.00 18.03 ? 78 GLU B CB 1 ATOM 3287 C CG . GLU B 2 78 ? 5.754 73.219 -70.845 1.00 22.23 ? 78 GLU B CG 1 ATOM 3288 C CD . GLU B 2 78 ? 6.510 72.226 -71.746 1.00 41.47 ? 78 GLU B CD 1 ATOM 3289 O OE1 . GLU B 2 78 ? 6.017 71.107 -71.942 1.00 46.74 ? 78 GLU B OE1 1 ATOM 3290 O OE2 . GLU B 2 78 ? 7.585 72.595 -72.287 1.00 39.30 ? 78 GLU B OE2 1 ATOM 3291 N N . ASN B 2 79 ? 6.621 76.582 -69.517 1.00 19.52 ? 79 ASN B N 1 ATOM 3292 C CA . ASN B 2 79 ? 7.360 76.935 -68.314 1.00 18.40 ? 79 ASN B CA 1 ATOM 3293 C C . ASN B 2 79 ? 6.549 77.814 -67.328 1.00 19.19 ? 79 ASN B C 1 ATOM 3294 O O . ASN B 2 79 ? 6.647 77.646 -66.113 1.00 23.02 ? 79 ASN B O 1 ATOM 3295 C CB . ASN B 2 79 ? 8.636 77.661 -68.720 1.00 18.09 ? 79 ASN B CB 1 ATOM 3296 C CG . ASN B 2 79 ? 9.520 77.948 -67.531 1.00 32.24 ? 79 ASN B CG 1 ATOM 3297 O OD1 . ASN B 2 79 ? 10.214 77.067 -67.011 1.00 41.99 ? 79 ASN B OD1 1 ATOM 3298 N ND2 . ASN B 2 79 ? 9.491 79.141 -67.090 1.00 29.37 ? 79 ASN B ND2 1 ATOM 3299 N N . LEU B 2 80 ? 5.757 78.751 -67.855 1.00 16.30 ? 80 LEU B N 1 ATOM 3300 C CA . LEU B 2 80 ? 4.926 79.613 -66.992 1.00 19.03 ? 80 LEU B CA 1 ATOM 3301 C C . LEU B 2 80 ? 3.923 78.673 -66.283 1.00 19.84 ? 80 LEU B C 1 ATOM 3302 O O . LEU B 2 80 ? 3.680 78.781 -65.073 1.00 18.97 ? 80 LEU B O 1 ATOM 3303 C CB . LEU B 2 80 ? 4.176 80.596 -67.912 1.00 19.24 ? 80 LEU B CB 1 ATOM 3304 C CG . LEU B 2 80 ? 3.473 81.745 -67.187 1.00 23.77 ? 80 LEU B CG 1 ATOM 3305 C CD1 . LEU B 2 80 ? 3.149 82.877 -68.236 1.00 25.16 ? 80 LEU B CD1 1 ATOM 3306 C CD2 . LEU B 2 80 ? 2.136 81.212 -66.566 1.00 26.77 ? 80 LEU B CD2 1 ATOM 3307 N N . ASN B 2 81 ? 3.330 77.749 -67.041 1.00 16.95 ? 81 ASN B N 1 ATOM 3308 C CA . ASN B 2 81 ? 2.338 76.815 -66.452 1.00 19.51 ? 81 ASN B CA 1 ATOM 3309 C C . ASN B 2 81 ? 3.004 76.019 -65.343 1.00 21.47 ? 81 ASN B C 1 ATOM 3310 O O . ASN B 2 81 ? 2.444 75.878 -64.241 1.00 19.88 ? 81 ASN B O 1 ATOM 3311 C CB . ASN B 2 81 ? 1.854 75.869 -67.551 1.00 20.54 ? 81 ASN B CB 1 ATOM 3312 C CG . ASN B 2 81 ? 0.781 74.922 -67.059 1.00 27.98 ? 81 ASN B CG 1 ATOM 3313 O OD1 . ASN B 2 81 ? -0.315 75.346 -66.735 1.00 24.73 ? 81 ASN B OD1 1 ATOM 3314 N ND2 . ASN B 2 81 ? 1.127 73.658 -66.929 1.00 24.54 ? 81 ASN B ND2 1 ATOM 3315 N N . LYS B 2 82 ? 4.189 75.465 -65.613 1.00 19.34 ? 82 LYS B N 1 ATOM 3316 C CA . LYS B 2 82 ? 4.894 74.670 -64.579 1.00 22.09 ? 82 LYS B CA 1 ATOM 3317 C C . LYS B 2 82 ? 5.200 75.477 -63.319 1.00 27.07 ? 82 LYS B C 1 ATOM 3318 O O . LYS B 2 82 ? 4.931 75.030 -62.183 1.00 24.26 ? 82 LYS B O 1 ATOM 3319 C CB . LYS B 2 82 ? 6.202 74.119 -65.165 1.00 23.77 ? 82 LYS B CB 1 ATOM 3320 C CG . LYS B 2 82 ? 7.083 73.373 -64.095 1.00 32.49 ? 82 LYS B CG 1 ATOM 3321 C CD . LYS B 2 82 ? 8.380 72.845 -64.700 1.00 44.82 ? 82 LYS B CD 1 ATOM 3322 C CE . LYS B 2 82 ? 9.522 72.977 -63.689 1.00 64.71 ? 82 LYS B CE 1 ATOM 3323 N NZ . LYS B 2 82 ? 9.211 72.205 -62.448 1.00 70.95 ? 82 LYS B NZ 1 ATOM 3324 N N . LYS B 2 83 ? 5.741 76.671 -63.501 1.00 20.78 ? 83 LYS B N 1 ATOM 3325 C CA . LYS B 2 83 ? 6.042 77.548 -62.348 1.00 22.78 ? 83 LYS B CA 1 ATOM 3326 C C . LYS B 2 83 ? 4.799 77.889 -61.552 1.00 23.29 ? 83 LYS B C 1 ATOM 3327 O O . LYS B 2 83 ? 4.865 77.938 -60.310 1.00 27.16 ? 83 LYS B O 1 ATOM 3328 C CB . LYS B 2 83 ? 6.735 78.833 -62.791 1.00 33.55 ? 83 LYS B CB 1 ATOM 3329 C CG . LYS B 2 83 ? 8.221 78.895 -62.464 1.00 47.26 ? 83 LYS B CG 1 ATOM 3330 C CD . LYS B 2 83 ? 9.013 77.693 -62.950 1.00 55.96 ? 83 LYS B CD 1 ATOM 3331 C CE . LYS B 2 83 ? 10.207 77.416 -62.008 1.00 78.10 ? 83 LYS B CE 1 ATOM 3332 N NZ . LYS B 2 83 ? 10.813 78.666 -61.384 1.00 57.68 ? 83 LYS B NZ 1 ATOM 3333 N N A MET B 2 84 ? 3.703 78.152 -62.225 0.45 20.85 ? 84 MET B N 1 ATOM 3334 N N B MET B 2 84 ? 3.687 78.146 -62.244 0.55 20.83 ? 84 MET B N 1 ATOM 3335 C CA A MET B 2 84 ? 2.505 78.496 -61.500 0.45 23.25 ? 84 MET B CA 1 ATOM 3336 C CA B MET B 2 84 ? 2.396 78.516 -61.621 0.55 23.21 ? 84 MET B CA 1 ATOM 3337 C C A MET B 2 84 ? 2.064 77.306 -60.654 0.45 24.51 ? 84 MET B C 1 ATOM 3338 C C B MET B 2 84 ? 1.861 77.368 -60.756 0.55 24.52 ? 84 MET B C 1 ATOM 3339 O O A MET B 2 84 ? 1.894 77.433 -59.418 0.45 23.49 ? 84 MET B O 1 ATOM 3340 O O B MET B 2 84 ? 1.438 77.583 -59.607 0.55 23.45 ? 84 MET B O 1 ATOM 3341 C CB A MET B 2 84 ? 1.400 78.840 -62.456 0.45 25.00 ? 84 MET B CB 1 ATOM 3342 C CB B MET B 2 84 ? 1.345 78.863 -62.687 0.55 24.99 ? 84 MET B CB 1 ATOM 3343 C CG A MET B 2 84 ? 0.332 79.615 -61.804 0.45 27.27 ? 84 MET B CG 1 ATOM 3344 C CG B MET B 2 84 ? 0.030 79.469 -62.170 0.55 20.94 ? 84 MET B CG 1 ATOM 3345 S SD A MET B 2 84 ? -1.077 79.504 -62.843 0.45 30.70 ? 84 MET B SD 1 ATOM 3346 S SD B MET B 2 84 ? -1.245 78.232 -61.806 0.55 24.79 ? 84 MET B SD 1 ATOM 3347 C CE A MET B 2 84 ? -1.864 78.086 -62.146 0.45 26.44 ? 84 MET B CE 1 ATOM 3348 C CE B MET B 2 84 ? -1.738 77.783 -63.484 0.55 17.00 ? 84 MET B CE 1 ATOM 3349 N N . GLU B 2 85 ? 1.879 76.159 -61.309 1.00 21.20 ? 85 GLU B N 1 ATOM 3350 C CA . GLU B 2 85 ? 1.385 74.996 -60.583 1.00 24.67 ? 85 GLU B CA 1 ATOM 3351 C C . GLU B 2 85 ? 2.297 74.634 -59.437 1.00 25.21 ? 85 GLU B C 1 ATOM 3352 O O . GLU B 2 85 ? 1.820 74.378 -58.318 1.00 26.75 ? 85 GLU B O 1 ATOM 3353 C CB . GLU B 2 85 ? 1.147 73.811 -61.520 1.00 27.49 ? 85 GLU B CB 1 ATOM 3354 C CG . GLU B 2 85 ? -0.030 74.173 -62.428 1.00 31.88 ? 85 GLU B CG 1 ATOM 3355 C CD . GLU B 2 85 ? -0.784 72.920 -62.868 1.00 37.63 ? 85 GLU B CD 1 ATOM 3356 O OE1 . GLU B 2 85 ? -0.102 71.886 -63.042 1.00 42.02 ? 85 GLU B OE1 1 ATOM 3357 O OE2 . GLU B 2 85 ? -2.012 72.999 -62.989 1.00 34.14 ? 85 GLU B OE2 1 ATOM 3358 N N . ASP B 2 86 ? 3.591 74.618 -59.679 1.00 28.35 ? 86 ASP B N 1 ATOM 3359 C CA . ASP B 2 86 ? 4.535 74.374 -58.611 1.00 28.36 ? 86 ASP B CA 1 ATOM 3360 C C . ASP B 2 86 ? 4.423 75.456 -57.516 1.00 28.87 ? 86 ASP B C 1 ATOM 3361 O O . ASP B 2 86 ? 4.578 75.187 -56.325 1.00 28.26 ? 86 ASP B O 1 ATOM 3362 C CB . ASP B 2 86 ? 5.970 74.425 -59.106 1.00 26.86 ? 86 ASP B CB 1 ATOM 3363 C CG . ASP B 2 86 ? 6.393 73.200 -59.942 1.00 44.70 ? 86 ASP B CG 1 ATOM 3364 O OD1 . ASP B 2 86 ? 5.580 72.260 -60.095 1.00 51.74 ? 86 ASP B OD1 1 ATOM 3365 O OD2 . ASP B 2 86 ? 7.555 73.204 -60.466 1.00 46.74 ? 86 ASP B OD2 1 ATOM 3366 N N . GLY B 2 87 ? 4.270 76.694 -57.936 1.00 21.98 ? 87 GLY B N 1 ATOM 3367 C CA . GLY B 2 87 ? 4.192 77.829 -57.016 1.00 24.80 ? 87 GLY B CA 1 ATOM 3368 C C . GLY B 2 87 ? 3.069 77.644 -56.025 1.00 28.23 ? 87 GLY B C 1 ATOM 3369 O O . GLY B 2 87 ? 3.296 77.816 -54.826 1.00 24.38 ? 87 GLY B O 1 ATOM 3370 N N . PHE B 2 88 ? 1.884 77.279 -56.494 1.00 23.83 ? 88 PHE B N 1 ATOM 3371 C CA . PHE B 2 88 ? 0.768 77.034 -55.568 1.00 23.58 ? 88 PHE B CA 1 ATOM 3372 C C . PHE B 2 88 ? 1.033 75.804 -54.718 1.00 29.67 ? 88 PHE B C 1 ATOM 3373 O O . PHE B 2 88 ? 0.652 75.759 -53.530 1.00 25.53 ? 88 PHE B O 1 ATOM 3374 C CB . PHE B 2 88 ? -0.581 76.904 -56.297 1.00 27.17 ? 88 PHE B CB 1 ATOM 3375 C CG . PHE B 2 88 ? -1.093 78.219 -56.814 1.00 25.29 ? 88 PHE B CG 1 ATOM 3376 C CD1 . PHE B 2 88 ? -1.234 78.473 -58.190 1.00 25.82 ? 88 PHE B CD1 1 ATOM 3377 C CD2 . PHE B 2 88 ? -1.397 79.253 -55.924 1.00 24.96 ? 88 PHE B CD2 1 ATOM 3378 C CE1 . PHE B 2 88 ? -1.664 79.719 -58.603 1.00 28.00 ? 88 PHE B CE1 1 ATOM 3379 C CE2 . PHE B 2 88 ? -1.848 80.502 -56.357 1.00 25.80 ? 88 PHE B CE2 1 ATOM 3380 C CZ . PHE B 2 88 ? -1.968 80.723 -57.688 1.00 30.18 ? 88 PHE B CZ 1 ATOM 3381 N N A LEU B 2 89 ? 1.664 74.805 -55.314 0.47 22.67 ? 89 LEU B N 1 ATOM 3382 N N B LEU B 2 89 ? 1.653 74.768 -55.288 0.53 22.69 ? 89 LEU B N 1 ATOM 3383 C CA A LEU B 2 89 ? 1.956 73.612 -54.558 0.47 24.70 ? 89 LEU B CA 1 ATOM 3384 C CA B LEU B 2 89 ? 1.847 73.571 -54.462 0.53 24.58 ? 89 LEU B CA 1 ATOM 3385 C C A LEU B 2 89 ? 2.777 74.024 -53.341 0.47 25.72 ? 89 LEU B C 1 ATOM 3386 C C B LEU B 2 89 ? 2.863 73.895 -53.338 0.53 25.77 ? 89 LEU B C 1 ATOM 3387 O O A LEU B 2 89 ? 2.460 73.675 -52.184 0.47 24.89 ? 89 LEU B O 1 ATOM 3388 O O B LEU B 2 89 ? 2.746 73.363 -52.211 0.53 24.85 ? 89 LEU B O 1 ATOM 3389 C CB A LEU B 2 89 ? 2.785 72.681 -55.405 0.47 27.51 ? 89 LEU B CB 1 ATOM 3390 C CB B LEU B 2 89 ? 2.276 72.330 -55.256 0.53 26.86 ? 89 LEU B CB 1 ATOM 3391 C CG A LEU B 2 89 ? 3.226 71.433 -54.691 0.47 24.53 ? 89 LEU B CG 1 ATOM 3392 C CG B LEU B 2 89 ? 1.469 71.653 -56.388 0.53 25.11 ? 89 LEU B CG 1 ATOM 3393 C CD1 A LEU B 2 89 ? 2.143 70.884 -53.776 0.47 25.53 ? 89 LEU B CD1 1 ATOM 3394 C CD1 B LEU B 2 89 ? 2.374 70.558 -56.943 0.53 26.50 ? 89 LEU B CD1 1 ATOM 3395 C CD2 A LEU B 2 89 ? 3.570 70.422 -55.823 0.47 24.05 ? 89 LEU B CD2 1 ATOM 3396 C CD2 B LEU B 2 89 ? 0.030 71.056 -56.076 0.53 25.21 ? 89 LEU B CD2 1 ATOM 3397 N N . ASP B 2 90 ? 3.835 74.774 -53.602 1.00 23.44 ? 90 ASP B N 1 ATOM 3398 C CA . ASP B 2 90 ? 4.734 75.178 -52.529 1.00 26.44 ? 90 ASP B CA 1 ATOM 3399 C C . ASP B 2 90 ? 4.055 76.045 -51.488 1.00 27.68 ? 90 ASP B C 1 ATOM 3400 O O . ASP B 2 90 ? 4.363 75.923 -50.312 1.00 22.19 ? 90 ASP B O 1 ATOM 3401 C CB . ASP B 2 90 ? 5.957 75.896 -53.068 1.00 27.84 ? 90 ASP B CB 1 ATOM 3402 C CG . ASP B 2 90 ? 6.836 74.955 -53.894 1.00 37.88 ? 90 ASP B CG 1 ATOM 3403 O OD1 . ASP B 2 90 ? 6.794 73.725 -53.670 1.00 31.28 ? 90 ASP B OD1 1 ATOM 3404 O OD2 . ASP B 2 90 ? 7.550 75.428 -54.776 1.00 37.33 ? 90 ASP B OD2 1 ATOM 3405 N N . VAL B 2 91 ? 3.204 76.965 -51.923 1.00 21.91 ? 91 VAL B N 1 ATOM 3406 C CA . VAL B 2 91 ? 2.459 77.816 -50.954 1.00 22.56 ? 91 VAL B CA 1 ATOM 3407 C C . VAL B 2 91 ? 1.627 76.906 -50.028 1.00 23.78 ? 91 VAL B C 1 ATOM 3408 O O . VAL B 2 91 ? 1.576 77.099 -48.797 1.00 22.20 ? 91 VAL B O 1 ATOM 3409 C CB . VAL B 2 91 ? 1.533 78.804 -51.648 1.00 24.75 ? 91 VAL B CB 1 ATOM 3410 C CG1 . VAL B 2 91 ? 0.520 79.423 -50.669 1.00 27.77 ? 91 VAL B CG1 1 ATOM 3411 C CG2 . VAL B 2 91 ? 2.394 79.897 -52.399 1.00 22.53 ? 91 VAL B CG2 1 ATOM 3412 N N . TRP B 2 92 ? 0.955 75.943 -50.612 1.00 21.51 ? 92 TRP B N 1 ATOM 3413 C CA . TRP B 2 92 ? 0.029 75.147 -49.795 1.00 21.20 ? 92 TRP B CA 1 ATOM 3414 C C . TRP B 2 92 ? 0.765 74.150 -48.913 1.00 21.84 ? 92 TRP B C 1 ATOM 3415 O O . TRP B 2 92 ? 0.283 73.849 -47.792 1.00 20.60 ? 92 TRP B O 1 ATOM 3416 C CB . TRP B 2 92 ? -1.048 74.463 -50.649 1.00 23.12 ? 92 TRP B CB 1 ATOM 3417 C CG . TRP B 2 92 ? -2.100 75.447 -51.077 1.00 21.88 ? 92 TRP B CG 1 ATOM 3418 C CD1 . TRP B 2 92 ? -2.217 76.009 -52.326 1.00 29.14 ? 92 TRP B CD1 1 ATOM 3419 C CD2 . TRP B 2 92 ? -3.107 76.100 -50.259 1.00 24.95 ? 92 TRP B CD2 1 ATOM 3420 N NE1 . TRP B 2 92 ? -3.265 76.902 -52.347 1.00 29.93 ? 92 TRP B NE1 1 ATOM 3421 C CE2 . TRP B 2 92 ? -3.840 76.964 -51.102 1.00 27.05 ? 92 TRP B CE2 1 ATOM 3422 C CE3 . TRP B 2 92 ? -3.488 75.988 -48.918 1.00 30.79 ? 92 TRP B CE3 1 ATOM 3423 C CZ2 . TRP B 2 92 ? -4.933 77.737 -50.644 1.00 27.03 ? 92 TRP B CZ2 1 ATOM 3424 C CZ3 . TRP B 2 92 ? -4.575 76.739 -48.461 1.00 25.58 ? 92 TRP B CZ3 1 ATOM 3425 C CH2 . TRP B 2 92 ? -5.291 77.606 -49.320 1.00 27.80 ? 92 TRP B CH2 1 ATOM 3426 N N . THR B 2 93 ? 1.921 73.671 -49.382 1.00 21.92 ? 93 THR B N 1 ATOM 3427 C CA . THR B 2 93 ? 2.762 72.782 -48.560 1.00 20.13 ? 93 THR B CA 1 ATOM 3428 C C . THR B 2 93 ? 3.236 73.560 -47.333 1.00 21.06 ? 93 THR B C 1 ATOM 3429 O O . THR B 2 93 ? 3.217 73.051 -46.183 1.00 20.05 ? 93 THR B O 1 ATOM 3430 C CB . THR B 2 93 ? 3.924 72.214 -49.354 1.00 21.36 ? 93 THR B CB 1 ATOM 3431 O OG1 . THR B 2 93 ? 3.393 71.398 -50.414 1.00 21.41 ? 93 THR B OG1 1 ATOM 3432 C CG2 . THR B 2 93 ? 4.849 71.335 -48.479 1.00 24.35 ? 93 THR B CG2 1 ATOM 3433 N N . TYR B 2 94 ? 3.670 74.787 -47.581 1.00 20.07 ? 94 TYR B N 1 ATOM 3434 C CA . TYR B 2 94 ? 4.102 75.665 -46.464 1.00 22.06 ? 94 TYR B CA 1 ATOM 3435 C C . TYR B 2 94 ? 2.963 75.913 -45.519 1.00 22.50 ? 94 TYR B C 1 ATOM 3436 O O . TYR B 2 94 ? 3.145 75.843 -44.279 1.00 21.98 ? 94 TYR B O 1 ATOM 3437 C CB . TYR B 2 94 ? 4.616 76.982 -47.071 1.00 21.30 ? 94 TYR B CB 1 ATOM 3438 C CG . TYR B 2 94 ? 4.785 78.114 -46.049 1.00 20.69 ? 94 TYR B CG 1 ATOM 3439 C CD1 . TYR B 2 94 ? 5.986 78.290 -45.383 1.00 23.70 ? 94 TYR B CD1 1 ATOM 3440 C CD2 . TYR B 2 94 ? 3.744 78.978 -45.775 1.00 23.83 ? 94 TYR B CD2 1 ATOM 3441 C CE1 . TYR B 2 94 ? 6.137 79.360 -44.467 1.00 27.08 ? 94 TYR B CE1 1 ATOM 3442 C CE2 . TYR B 2 94 ? 3.901 80.050 -44.855 1.00 23.48 ? 94 TYR B CE2 1 ATOM 3443 C CZ . TYR B 2 94 ? 5.104 80.203 -44.223 1.00 27.22 ? 94 TYR B CZ 1 ATOM 3444 O OH . TYR B 2 94 ? 5.271 81.244 -43.311 1.00 30.10 ? 94 TYR B OH 1 ATOM 3445 N N . ASN B 2 95 ? 1.795 76.223 -46.043 1.00 20.37 ? 95 ASN B N 1 ATOM 3446 C CA . ASN B 2 95 ? 0.660 76.603 -45.171 1.00 23.18 ? 95 ASN B CA 1 ATOM 3447 C C . ASN B 2 95 ? 0.346 75.409 -44.249 1.00 23.88 ? 95 ASN B C 1 ATOM 3448 O O . ASN B 2 95 ? 0.142 75.562 -43.056 1.00 21.66 ? 95 ASN B O 1 ATOM 3449 C CB . ASN B 2 95 ? -0.600 76.933 -45.965 1.00 25.23 ? 95 ASN B CB 1 ATOM 3450 C CG . ASN B 2 95 ? -0.552 78.332 -46.637 1.00 27.45 ? 95 ASN B CG 1 ATOM 3451 O OD1 . ASN B 2 95 ? 0.227 79.177 -46.243 1.00 26.26 ? 95 ASN B OD1 1 ATOM 3452 N ND2 . ASN B 2 95 ? -1.498 78.584 -47.587 1.00 28.54 ? 95 ASN B ND2 1 ATOM 3453 N N . ALA B 2 96 ? 0.340 74.194 -44.822 1.00 18.59 ? 96 ALA B N 1 ATOM 3454 C CA . ALA B 2 96 ? -0.015 72.994 -44.031 1.00 19.45 ? 96 ALA B CA 1 ATOM 3455 C C . ALA B 2 96 ? 1.042 72.649 -43.011 1.00 18.17 ? 96 ALA B C 1 ATOM 3456 O O . ALA B 2 96 ? 0.707 72.388 -41.831 1.00 18.52 ? 96 ALA B O 1 ATOM 3457 C CB . ALA B 2 96 ? -0.257 71.789 -44.982 1.00 20.72 ? 96 ALA B CB 1 ATOM 3458 N N . GLU B 2 97 ? 2.319 72.663 -43.413 1.00 19.03 ? 97 GLU B N 1 ATOM 3459 C CA . GLU B 2 97 ? 3.374 72.261 -42.448 1.00 16.85 ? 97 GLU B CA 1 ATOM 3460 C C . GLU B 2 97 ? 3.443 73.285 -41.321 1.00 19.60 ? 97 GLU B C 1 ATOM 3461 O O . GLU B 2 97 ? 3.583 72.920 -40.131 1.00 19.56 ? 97 GLU B O 1 ATOM 3462 C CB . GLU B 2 97 ? 4.752 72.147 -43.106 1.00 20.47 ? 97 GLU B CB 1 ATOM 3463 C CG . GLU B 2 97 ? 4.755 70.944 -44.109 1.00 22.71 ? 97 GLU B CG 1 ATOM 3464 C CD . GLU B 2 97 ? 6.044 70.706 -44.816 1.00 30.29 ? 97 GLU B CD 1 ATOM 3465 O OE1 . GLU B 2 97 ? 7.029 71.441 -44.582 1.00 31.21 ? 97 GLU B OE1 1 ATOM 3466 O OE2 . GLU B 2 97 ? 6.054 69.772 -45.666 1.00 25.39 ? 97 GLU B OE2 1 ATOM 3467 N N . LEU B 2 98 ? 3.359 74.562 -41.691 1.00 19.58 ? 98 LEU B N 1 ATOM 3468 C CA . LEU B 2 98 ? 3.484 75.607 -40.661 1.00 21.19 ? 98 LEU B CA 1 ATOM 3469 C C . LEU B 2 98 ? 2.310 75.617 -39.699 1.00 18.65 ? 98 LEU B C 1 ATOM 3470 O O . LEU B 2 98 ? 2.519 75.750 -38.453 1.00 19.00 ? 98 LEU B O 1 ATOM 3471 C CB . LEU B 2 98 ? 3.679 76.983 -41.296 1.00 25.08 ? 98 LEU B CB 1 ATOM 3472 C CG . LEU B 2 98 ? 3.831 78.115 -40.313 1.00 25.44 ? 98 LEU B CG 1 ATOM 3473 C CD1 . LEU B 2 98 ? 5.208 77.922 -39.675 1.00 25.76 ? 98 LEU B CD1 1 ATOM 3474 C CD2 . LEU B 2 98 ? 3.677 79.474 -41.082 1.00 27.26 ? 98 LEU B CD2 1 ATOM 3475 N N . LEU B 2 99 ? 1.124 75.498 -40.243 1.00 19.97 ? 99 LEU B N 1 ATOM 3476 C CA . LEU B 2 99 ? -0.088 75.493 -39.409 1.00 21.47 ? 99 LEU B CA 1 ATOM 3477 C C . LEU B 2 99 ? -0.023 74.323 -38.406 1.00 18.81 ? 99 LEU B C 1 ATOM 3478 O O . LEU B 2 99 ? -0.337 74.470 -37.201 1.00 18.74 ? 99 LEU B O 1 ATOM 3479 C CB . LEU B 2 99 ? -1.336 75.396 -40.268 1.00 21.48 ? 99 LEU B CB 1 ATOM 3480 C CG . LEU B 2 99 ? -2.637 75.475 -39.393 1.00 22.44 ? 99 LEU B CG 1 ATOM 3481 C CD1 . LEU B 2 99 ? -2.651 76.732 -38.546 1.00 24.88 ? 99 LEU B CD1 1 ATOM 3482 C CD2 . LEU B 2 99 ? -3.850 75.413 -40.289 1.00 29.47 ? 99 LEU B CD2 1 ATOM 3483 N N . VAL B 2 100 ? 0.370 73.142 -38.895 1.00 20.06 ? 100 VAL B N 1 ATOM 3484 C CA . VAL B 2 100 ? 0.484 72.011 -37.999 1.00 19.19 ? 100 VAL B CA 1 ATOM 3485 C C . VAL B 2 100 ? 1.549 72.255 -36.864 1.00 17.35 ? 100 VAL B C 1 ATOM 3486 O O . VAL B 2 100 ? 1.275 71.968 -35.679 1.00 18.35 ? 100 VAL B O 1 ATOM 3487 C CB . VAL B 2 100 ? 0.779 70.677 -38.792 1.00 18.45 ? 100 VAL B CB 1 ATOM 3488 C CG1 . VAL B 2 100 ? 1.236 69.555 -37.800 1.00 19.01 ? 100 VAL B CG1 1 ATOM 3489 C CG2 . VAL B 2 100 ? -0.506 70.289 -39.636 1.00 19.98 ? 100 VAL B CG2 1 ATOM 3490 N N . LEU B 2 101 ? 2.717 72.833 -37.188 1.00 16.71 ? 101 LEU B N 1 ATOM 3491 C CA . LEU B 2 101 ? 3.735 73.058 -36.115 1.00 16.28 ? 101 LEU B CA 1 ATOM 3492 C C . LEU B 2 101 ? 3.215 74.116 -35.132 1.00 17.91 ? 101 LEU B C 1 ATOM 3493 O O . LEU B 2 101 ? 3.379 73.953 -33.892 1.00 19.91 ? 101 LEU B O 1 ATOM 3494 C CB . LEU B 2 101 ? 5.050 73.623 -36.740 1.00 18.17 ? 101 LEU B CB 1 ATOM 3495 C CG . LEU B 2 101 ? 5.811 72.628 -37.636 1.00 20.79 ? 101 LEU B CG 1 ATOM 3496 C CD1 . LEU B 2 101 ? 7.166 73.304 -38.080 1.00 23.58 ? 101 LEU B CD1 1 ATOM 3497 C CD2 . LEU B 2 101 ? 6.150 71.361 -36.882 1.00 18.15 ? 101 LEU B CD2 1 ATOM 3498 N N . MET B 2 102 ? 2.597 75.167 -35.655 1.00 17.45 ? 102 MET B N 1 ATOM 3499 C CA . MET B 2 102 ? 2.081 76.216 -34.771 1.00 19.01 ? 102 MET B CA 1 ATOM 3500 C C . MET B 2 102 ? 0.968 75.694 -33.880 1.00 21.83 ? 102 MET B C 1 ATOM 3501 O O . MET B 2 102 ? 0.957 75.971 -32.670 1.00 21.04 ? 102 MET B O 1 ATOM 3502 C CB . MET B 2 102 ? 1.553 77.424 -35.611 1.00 17.66 ? 102 MET B CB 1 ATOM 3503 C CG . MET B 2 102 ? 2.808 78.151 -36.178 1.00 21.05 ? 102 MET B CG 1 ATOM 3504 S SD . MET B 2 102 ? 2.166 79.619 -37.130 1.00 27.42 ? 102 MET B SD 1 ATOM 3505 C CE . MET B 2 102 ? 0.730 79.984 -36.182 1.00 47.74 ? 102 MET B CE 1 ATOM 3506 N N . GLU B 2 103 ? 0.026 74.971 -34.451 1.00 19.46 ? 103 GLU B N 1 ATOM 3507 C CA . GLU B 2 103 ? -1.076 74.490 -33.641 1.00 19.42 ? 103 GLU B CA 1 ATOM 3508 C C . GLU B 2 103 ? -0.620 73.412 -32.683 1.00 18.18 ? 103 GLU B C 1 ATOM 3509 O O . GLU B 2 103 ? -1.205 73.320 -31.588 1.00 19.72 ? 103 GLU B O 1 ATOM 3510 C CB . GLU B 2 103 ? -2.245 74.011 -34.499 1.00 18.95 ? 103 GLU B CB 1 ATOM 3511 C CG . GLU B 2 103 ? -2.994 75.233 -35.083 1.00 24.71 ? 103 GLU B CG 1 ATOM 3512 C CD . GLU B 2 103 ? -3.500 76.220 -33.989 1.00 28.87 ? 103 GLU B CD 1 ATOM 3513 O OE1 . GLU B 2 103 ? -3.899 75.795 -32.867 1.00 26.91 ? 103 GLU B OE1 1 ATOM 3514 O OE2 . GLU B 2 103 ? -3.542 77.440 -34.286 1.00 26.83 ? 103 GLU B OE2 1 ATOM 3515 N N . ASN B 2 104 ? 0.375 72.597 -33.071 1.00 16.91 ? 104 ASN B N 1 ATOM 3516 C CA . ASN B 2 104 ? 0.892 71.590 -32.134 1.00 18.46 ? 104 ASN B CA 1 ATOM 3517 C C . ASN B 2 104 ? 1.504 72.284 -30.912 1.00 16.56 ? 104 ASN B C 1 ATOM 3518 O O . ASN B 2 104 ? 1.282 71.854 -29.772 1.00 17.75 ? 104 ASN B O 1 ATOM 3519 C CB . ASN B 2 104 ? 1.967 70.705 -32.792 1.00 15.86 ? 104 ASN B CB 1 ATOM 3520 C CG . ASN B 2 104 ? 1.332 69.670 -33.718 1.00 18.54 ? 104 ASN B CG 1 ATOM 3521 O OD1 . ASN B 2 104 ? 0.095 69.510 -33.717 1.00 17.86 ? 104 ASN B OD1 1 ATOM 3522 N ND2 . ASN B 2 104 ? 2.144 68.914 -34.424 1.00 17.46 ? 104 ASN B ND2 1 ATOM 3523 N N . GLU B 2 105 ? 2.275 73.339 -31.138 1.00 16.27 ? 105 GLU B N 1 ATOM 3524 C CA A GLU B 2 105 ? 2.822 74.090 -30.008 0.50 19.88 ? 105 GLU B CA 1 ATOM 3525 C CA B GLU B 2 105 ? 2.805 74.121 -30.015 0.50 19.87 ? 105 GLU B CA 1 ATOM 3526 C C . GLU B 2 105 ? 1.689 74.547 -29.083 1.00 20.96 ? 105 GLU B C 1 ATOM 3527 O O . GLU B 2 105 ? 1.784 74.402 -27.836 1.00 19.19 ? 105 GLU B O 1 ATOM 3528 C CB A GLU B 2 105 ? 3.685 75.257 -30.532 0.50 19.42 ? 105 GLU B CB 1 ATOM 3529 C CB B GLU B 2 105 ? 3.555 75.354 -30.538 0.50 19.40 ? 105 GLU B CB 1 ATOM 3530 C CG A GLU B 2 105 ? 4.507 75.967 -29.424 0.50 23.05 ? 105 GLU B CG 1 ATOM 3531 C CG B GLU B 2 105 ? 4.109 76.218 -29.393 0.50 22.26 ? 105 GLU B CG 1 ATOM 3532 C CD A GLU B 2 105 ? 6.034 75.660 -29.439 0.50 23.09 ? 105 GLU B CD 1 ATOM 3533 C CD B GLU B 2 105 ? 5.107 77.266 -29.884 0.50 28.85 ? 105 GLU B CD 1 ATOM 3534 O OE1 A GLU B 2 105 ? 6.568 75.542 -28.318 0.50 23.74 ? 105 GLU B OE1 1 ATOM 3535 O OE1 B GLU B 2 105 ? 5.206 77.491 -31.097 0.50 33.21 ? 105 GLU B OE1 1 ATOM 3536 O OE2 A GLU B 2 105 ? 6.700 75.553 -30.498 0.50 16.87 ? 105 GLU B OE2 1 ATOM 3537 O OE2 B GLU B 2 105 ? 5.828 77.858 -29.039 0.50 35.43 ? 105 GLU B OE2 1 ATOM 3538 N N . ARG B 2 106 ? 0.623 75.099 -29.676 1.00 18.25 ? 106 ARG B N 1 ATOM 3539 C CA . ARG B 2 106 ? -0.488 75.622 -28.880 1.00 19.80 ? 106 ARG B CA 1 ATOM 3540 C C . ARG B 2 106 ? -1.245 74.494 -28.165 1.00 23.02 ? 106 ARG B C 1 ATOM 3541 O O . ARG B 2 106 ? -1.720 74.657 -27.039 1.00 19.24 ? 106 ARG B O 1 ATOM 3542 C CB . ARG B 2 106 ? -1.456 76.436 -29.776 1.00 18.63 ? 106 ARG B CB 1 ATOM 3543 C CG . ARG B 2 106 ? -0.812 77.751 -30.192 1.00 23.03 ? 106 ARG B CG 1 ATOM 3544 C CD . ARG B 2 106 ? -1.414 78.291 -31.445 1.00 36.01 ? 106 ARG B CD 1 ATOM 3545 N NE . ARG B 2 106 ? -0.674 79.345 -32.184 1.00 57.38 ? 106 ARG B NE 1 ATOM 3546 C CZ . ARG B 2 106 ? 0.651 79.480 -32.444 1.00 58.43 ? 106 ARG B CZ 1 ATOM 3547 N NH1 . ARG B 2 106 ? 1.641 78.666 -32.012 1.00 39.09 ? 106 ARG B NH1 1 ATOM 3548 N NH2 . ARG B 2 106 ? 1.005 80.516 -33.177 1.00 57.08 ? 106 ARG B NH2 1 ATOM 3549 N N . THR B 2 107 ? -1.411 73.354 -28.826 1.00 18.11 ? 107 THR B N 1 ATOM 3550 C CA . THR B 2 107 ? -2.145 72.244 -28.153 1.00 16.25 ? 107 THR B CA 1 ATOM 3551 C C . THR B 2 107 ? -1.388 71.775 -26.891 1.00 14.09 ? 107 THR B C 1 ATOM 3552 O O . THR B 2 107 ? -2.049 71.522 -25.859 1.00 16.13 ? 107 THR B O 1 ATOM 3553 C CB . THR B 2 107 ? -2.294 71.068 -29.160 1.00 15.96 ? 107 THR B CB 1 ATOM 3554 O OG1 . THR B 2 107 ? -3.195 71.483 -30.202 1.00 19.44 ? 107 THR B OG1 1 ATOM 3555 C CG2 . THR B 2 107 ? -2.868 69.838 -28.454 1.00 19.14 ? 107 THR B CG2 1 ATOM 3556 N N . LEU B 2 108 ? -0.070 71.645 -26.971 1.00 15.31 ? 108 LEU B N 1 ATOM 3557 C CA . LEU B 2 108 ? 0.624 71.083 -25.806 1.00 17.17 ? 108 LEU B CA 1 ATOM 3558 C C . LEU B 2 108 ? 0.592 72.132 -24.671 1.00 18.12 ? 108 LEU B C 1 ATOM 3559 O O . LEU B 2 108 ? 0.350 71.759 -23.501 1.00 17.17 ? 108 LEU B O 1 ATOM 3560 C CB . LEU B 2 108 ? 2.079 70.832 -26.167 1.00 17.22 ? 108 LEU B CB 1 ATOM 3561 C CG . LEU B 2 108 ? 2.243 69.687 -27.216 1.00 18.32 ? 108 LEU B CG 1 ATOM 3562 C CD1 . LEU B 2 108 ? 3.745 69.511 -27.475 1.00 24.29 ? 108 LEU B CD1 1 ATOM 3563 C CD2 . LEU B 2 108 ? 1.480 68.375 -26.811 1.00 22.13 ? 108 LEU B CD2 1 ATOM 3564 N N . ASP B 2 109 ? 0.693 73.417 -25.021 1.00 18.22 ? 109 ASP B N 1 ATOM 3565 C CA . ASP B 2 109 ? 0.560 74.452 -23.949 1.00 18.84 ? 109 ASP B CA 1 ATOM 3566 C C . ASP B 2 109 ? -0.848 74.570 -23.387 1.00 16.74 ? 109 ASP B C 1 ATOM 3567 O O . ASP B 2 109 ? -1.022 74.886 -22.203 1.00 17.65 ? 109 ASP B O 1 ATOM 3568 C CB . ASP B 2 109 ? 1.044 75.812 -24.446 1.00 19.03 ? 109 ASP B CB 1 ATOM 3569 C CG . ASP B 2 109 ? 2.614 75.807 -24.655 1.00 21.67 ? 109 ASP B CG 1 ATOM 3570 O OD1 . ASP B 2 109 ? 3.000 76.452 -25.614 1.00 24.51 ? 109 ASP B OD1 1 ATOM 3571 O OD2 . ASP B 2 109 ? 3.373 75.233 -23.802 1.00 28.13 ? 109 ASP B OD2 1 ATOM 3572 N N . PHE B 2 110 ? -1.849 74.308 -24.237 1.00 15.56 ? 110 PHE B N 1 ATOM 3573 C CA . PHE B 2 110 ? -3.259 74.286 -23.790 1.00 15.89 ? 110 PHE B CA 1 ATOM 3574 C C . PHE B 2 110 ? -3.462 73.221 -22.683 1.00 13.89 ? 110 PHE B C 1 ATOM 3575 O O . PHE B 2 110 ? -4.091 73.481 -21.648 1.00 15.14 ? 110 PHE B O 1 ATOM 3576 C CB . PHE B 2 110 ? -4.136 74.008 -25.018 1.00 17.14 ? 110 PHE B CB 1 ATOM 3577 C CG . PHE B 2 110 ? -5.610 73.846 -24.719 1.00 16.19 ? 110 PHE B CG 1 ATOM 3578 C CD1 . PHE B 2 110 ? -6.311 74.810 -23.983 1.00 17.84 ? 110 PHE B CD1 1 ATOM 3579 C CD2 . PHE B 2 110 ? -6.323 72.777 -25.267 1.00 18.86 ? 110 PHE B CD2 1 ATOM 3580 C CE1 . PHE B 2 110 ? -7.701 74.687 -23.729 1.00 17.91 ? 110 PHE B CE1 1 ATOM 3581 C CE2 . PHE B 2 110 ? -7.695 72.636 -25.040 1.00 16.07 ? 110 PHE B CE2 1 ATOM 3582 C CZ . PHE B 2 110 ? -8.421 73.594 -24.312 1.00 19.84 ? 110 PHE B CZ 1 ATOM 3583 N N . HIS B 2 111 ? -2.943 72.003 -22.915 1.00 17.76 ? 111 HIS B N 1 ATOM 3584 C CA . HIS B 2 111 ? -2.990 71.000 -21.843 1.00 17.56 ? 111 HIS B CA 1 ATOM 3585 C C . HIS B 2 111 ? -2.317 71.482 -20.564 1.00 15.68 ? 111 HIS B C 1 ATOM 3586 O O . HIS B 2 111 ? -2.849 71.259 -19.483 1.00 16.14 ? 111 HIS B O 1 ATOM 3587 C CB . HIS B 2 111 ? -2.322 69.690 -22.281 1.00 17.10 ? 111 HIS B CB 1 ATOM 3588 C CG . HIS B 2 111 ? -3.094 68.991 -23.371 1.00 17.80 ? 111 HIS B CG 1 ATOM 3589 N ND1 . HIS B 2 111 ? -4.374 68.532 -23.163 1.00 20.99 ? 111 HIS B ND1 1 ATOM 3590 C CD2 . HIS B 2 111 ? -2.736 68.591 -24.615 1.00 19.06 ? 111 HIS B CD2 1 ATOM 3591 C CE1 . HIS B 2 111 ? -4.796 67.929 -24.261 1.00 16.75 ? 111 HIS B CE1 1 ATOM 3592 N NE2 . HIS B 2 111 ? -3.818 67.928 -25.144 1.00 18.56 ? 111 HIS B NE2 1 ATOM 3593 N N . ASP B 2 112 ? -1.156 72.126 -20.695 1.00 14.70 ? 112 ASP B N 1 ATOM 3594 C CA . ASP B 2 112 ? -0.418 72.596 -19.504 1.00 17.57 ? 112 ASP B CA 1 ATOM 3595 C C . ASP B 2 112 ? -1.289 73.635 -18.767 1.00 17.34 ? 112 ASP B C 1 ATOM 3596 O O . ASP B 2 112 ? -1.461 73.553 -17.559 1.00 16.54 ? 112 ASP B O 1 ATOM 3597 C CB . ASP B 2 112 ? 0.869 73.201 -20.007 1.00 17.44 ? 112 ASP B CB 1 ATOM 3598 C CG . ASP B 2 112 ? 1.887 73.484 -18.891 1.00 21.47 ? 112 ASP B CG 1 ATOM 3599 O OD1 . ASP B 2 112 ? 2.838 74.188 -19.225 1.00 22.37 ? 112 ASP B OD1 1 ATOM 3600 O OD2 . ASP B 2 112 ? 1.724 72.981 -17.748 1.00 18.08 ? 112 ASP B OD2 1 ATOM 3601 N N . SER B 2 113 ? -1.890 74.532 -19.542 1.00 15.18 ? 113 SER B N 1 ATOM 3602 C CA . SER B 2 113 ? -2.816 75.543 -18.975 1.00 16.64 ? 113 SER B CA 1 ATOM 3603 C C . SER B 2 113 ? -3.990 74.860 -18.239 1.00 17.33 ? 113 SER B C 1 ATOM 3604 O O . SER B 2 113 ? -4.359 75.252 -17.119 1.00 17.15 ? 113 SER B O 1 ATOM 3605 C CB . SER B 2 113 ? -3.335 76.501 -20.050 1.00 16.58 ? 113 SER B CB 1 ATOM 3606 O OG . SER B 2 113 ? -4.488 77.192 -19.571 1.00 19.29 ? 113 SER B OG 1 ATOM 3607 N N . ASN B 2 114 ? -4.543 73.817 -18.853 1.00 15.45 ? 114 ASN B N 1 ATOM 3608 C CA . ASN B 2 114 ? -5.649 73.173 -18.212 1.00 17.22 ? 114 ASN B CA 1 ATOM 3609 C C . ASN B 2 114 ? -5.265 72.530 -16.868 1.00 15.38 ? 114 ASN B C 1 ATOM 3610 O O . ASN B 2 114 ? -6.079 72.581 -15.931 1.00 16.73 ? 114 ASN B O 1 ATOM 3611 C CB . ASN B 2 114 ? -6.330 72.122 -19.125 1.00 16.47 ? 114 ASN B CB 1 ATOM 3612 C CG . ASN B 2 114 ? -6.996 72.744 -20.317 1.00 19.80 ? 114 ASN B CG 1 ATOM 3613 O OD1 . ASN B 2 114 ? -7.491 73.846 -20.250 1.00 19.35 ? 114 ASN B OD1 1 ATOM 3614 N ND2 . ASN B 2 114 ? -6.975 72.037 -21.435 1.00 18.14 ? 114 ASN B ND2 1 ATOM 3615 N N . VAL B 2 115 ? -4.059 71.935 -16.810 1.00 14.29 ? 115 VAL B N 1 ATOM 3616 C CA . VAL B 2 115 ? -3.610 71.340 -15.549 1.00 17.27 ? 115 VAL B CA 1 ATOM 3617 C C . VAL B 2 115 ? -3.368 72.434 -14.510 1.00 17.42 ? 115 VAL B C 1 ATOM 3618 O O . VAL B 2 115 ? -3.819 72.322 -13.368 1.00 16.40 ? 115 VAL B O 1 ATOM 3619 C CB . VAL B 2 115 ? -2.328 70.541 -15.745 1.00 17.75 ? 115 VAL B CB 1 ATOM 3620 C CG1 . VAL B 2 115 ? -1.819 70.022 -14.410 1.00 17.52 ? 115 VAL B CG1 1 ATOM 3621 C CG2 . VAL B 2 115 ? -2.635 69.294 -16.685 1.00 16.58 ? 115 VAL B CG2 1 ATOM 3622 N N A LYS B 2 116 ? -2.656 73.482 -14.902 0.48 17.50 ? 116 LYS B N 1 ATOM 3623 N N B LYS B 2 116 ? -2.648 73.478 -14.901 0.52 17.47 ? 116 LYS B N 1 ATOM 3624 C CA A LYS B 2 116 ? -2.478 74.589 -13.980 0.48 18.07 ? 116 LYS B CA 1 ATOM 3625 C CA B LYS B 2 116 ? -2.470 74.596 -13.990 0.52 18.10 ? 116 LYS B CA 1 ATOM 3626 C C A LYS B 2 116 ? -3.809 75.157 -13.434 0.48 18.29 ? 116 LYS B C 1 ATOM 3627 C C B LYS B 2 116 ? -3.805 75.158 -13.437 0.52 18.31 ? 116 LYS B C 1 ATOM 3628 O O A LYS B 2 116 ? -3.958 75.369 -12.234 0.48 18.66 ? 116 LYS B O 1 ATOM 3629 O O B LYS B 2 116 ? -3.953 75.367 -12.238 0.52 18.70 ? 116 LYS B O 1 ATOM 3630 C CB A LYS B 2 116 ? -1.658 75.705 -14.644 0.48 17.52 ? 116 LYS B CB 1 ATOM 3631 C CB B LYS B 2 116 ? -1.661 75.712 -14.678 0.52 17.30 ? 116 LYS B CB 1 ATOM 3632 C CG A LYS B 2 116 ? -1.543 76.961 -13.695 0.48 19.76 ? 116 LYS B CG 1 ATOM 3633 C CG B LYS B 2 116 ? -1.569 77.012 -13.772 0.52 23.82 ? 116 LYS B CG 1 ATOM 3634 C CD A LYS B 2 116 ? -0.729 78.040 -14.362 0.48 24.07 ? 116 LYS B CD 1 ATOM 3635 C CD B LYS B 2 116 ? -0.677 76.799 -12.550 0.52 34.83 ? 116 LYS B CD 1 ATOM 3636 C CE A LYS B 2 116 ? -0.361 79.145 -13.360 0.48 36.36 ? 116 LYS B CE 1 ATOM 3637 C CE B LYS B 2 116 ? -0.153 78.157 -12.014 0.52 38.34 ? 116 LYS B CE 1 ATOM 3638 N NZ A LYS B 2 116 ? -1.534 79.683 -12.620 0.48 36.70 ? 116 LYS B NZ 1 ATOM 3639 N NZ B LYS B 2 116 ? -1.132 79.279 -12.138 0.52 38.41 ? 116 LYS B NZ 1 ATOM 3640 N N . ASN B 2 117 ? -4.780 75.418 -14.307 1.00 16.65 ? 117 ASN B N 1 ATOM 3641 C CA . ASN B 2 117 ? -6.044 75.980 -13.862 1.00 16.34 ? 117 ASN B CA 1 ATOM 3642 C C . ASN B 2 117 ? -6.799 75.009 -12.940 1.00 18.91 ? 117 ASN B C 1 ATOM 3643 O O . ASN B 2 117 ? -7.487 75.448 -12.007 1.00 18.45 ? 117 ASN B O 1 ATOM 3644 C CB . ASN B 2 117 ? -6.912 76.293 -15.064 1.00 17.80 ? 117 ASN B CB 1 ATOM 3645 C CG . ASN B 2 117 ? -6.383 77.468 -15.859 1.00 21.19 ? 117 ASN B CG 1 ATOM 3646 O OD1 . ASN B 2 117 ? -5.556 78.213 -15.374 1.00 22.28 ? 117 ASN B OD1 1 ATOM 3647 N ND2 . ASN B 2 117 ? -6.880 77.618 -17.127 1.00 21.52 ? 117 ASN B ND2 1 ATOM 3648 N N . LEU B 2 118 ? -6.693 73.684 -13.209 1.00 18.10 ? 118 LEU B N 1 ATOM 3649 C CA . LEU B 2 118 ? -7.318 72.712 -12.279 1.00 18.19 ? 118 LEU B CA 1 ATOM 3650 C C . LEU B 2 118 ? -6.680 72.786 -10.886 1.00 19.29 ? 118 LEU B C 1 ATOM 3651 O O . LEU B 2 118 ? -7.368 72.813 -9.877 1.00 18.95 ? 118 LEU B O 1 ATOM 3652 C CB . LEU B 2 118 ? -7.249 71.262 -12.862 1.00 17.81 ? 118 LEU B CB 1 ATOM 3653 C CG . LEU B 2 118 ? -7.945 70.168 -12.034 1.00 22.97 ? 118 LEU B CG 1 ATOM 3654 C CD1 . LEU B 2 118 ? -9.408 70.452 -12.049 1.00 27.16 ? 118 LEU B CD1 1 ATOM 3655 C CD2 . LEU B 2 118 ? -7.704 68.840 -12.768 1.00 27.39 ? 118 LEU B CD2 1 ATOM 3656 N N . TYR B 2 119 ? -5.358 72.839 -10.856 1.00 19.09 ? 119 TYR B N 1 ATOM 3657 C CA . TYR B 2 119 ? -4.652 72.967 -9.585 1.00 20.55 ? 119 TYR B CA 1 ATOM 3658 C C . TYR B 2 119 ? -5.109 74.248 -8.880 1.00 20.31 ? 119 TYR B C 1 ATOM 3659 O O . TYR B 2 119 ? -5.376 74.273 -7.670 1.00 20.01 ? 119 TYR B O 1 ATOM 3660 C CB . TYR B 2 119 ? -3.152 73.028 -9.876 1.00 19.12 ? 119 TYR B CB 1 ATOM 3661 C CG . TYR B 2 119 ? -2.323 73.199 -8.600 1.00 20.07 ? 119 TYR B CG 1 ATOM 3662 C CD1 . TYR B 2 119 ? -2.029 72.096 -7.795 1.00 19.72 ? 119 TYR B CD1 1 ATOM 3663 C CD2 . TYR B 2 119 ? -1.880 74.437 -8.221 1.00 20.49 ? 119 TYR B CD2 1 ATOM 3664 C CE1 . TYR B 2 119 ? -1.257 72.239 -6.642 1.00 18.45 ? 119 TYR B CE1 1 ATOM 3665 C CE2 . TYR B 2 119 ? -1.132 74.610 -7.047 1.00 23.27 ? 119 TYR B CE2 1 ATOM 3666 C CZ . TYR B 2 119 ? -0.813 73.512 -6.283 1.00 24.04 ? 119 TYR B CZ 1 ATOM 3667 O OH . TYR B 2 119 ? -0.051 73.700 -5.131 1.00 22.65 ? 119 TYR B OH 1 ATOM 3668 N N . ASP B 2 120 ? -5.132 75.344 -9.604 1.00 18.56 ? 120 ASP B N 1 ATOM 3669 C CA . ASP B 2 120 ? -5.572 76.607 -8.941 1.00 20.88 ? 120 ASP B CA 1 ATOM 3670 C C . ASP B 2 120 ? -7.036 76.555 -8.493 1.00 21.39 ? 120 ASP B C 1 ATOM 3671 O O . ASP B 2 120 ? -7.407 77.167 -7.480 1.00 22.57 ? 120 ASP B O 1 ATOM 3672 C CB . ASP B 2 120 ? -5.345 77.803 -9.866 1.00 21.05 ? 120 ASP B CB 1 ATOM 3673 C CG . ASP B 2 120 ? -3.888 78.147 -10.013 1.00 26.53 ? 120 ASP B CG 1 ATOM 3674 O OD1 . ASP B 2 120 ? -3.097 77.884 -9.070 1.00 26.27 ? 120 ASP B OD1 1 ATOM 3675 O OD2 . ASP B 2 120 ? -3.496 78.660 -11.077 1.00 28.05 ? 120 ASP B OD2 1 ATOM 3676 N N . LYS B 2 121 ? -7.899 75.851 -9.236 1.00 20.15 ? 121 LYS B N 1 ATOM 3677 C CA . LYS B 2 121 ? -9.307 75.732 -8.845 1.00 24.10 ? 121 LYS B CA 1 ATOM 3678 C C . LYS B 2 121 ? -9.377 75.061 -7.465 1.00 25.35 ? 121 LYS B C 1 ATOM 3679 O O . LYS B 2 121 ? -10.154 75.478 -6.589 1.00 22.36 ? 121 LYS B O 1 ATOM 3680 C CB . LYS B 2 121 ? -10.062 74.895 -9.907 1.00 25.76 ? 121 LYS B CB 1 ATOM 3681 C CG . LYS B 2 121 ? -11.537 74.587 -9.583 1.00 30.17 ? 121 LYS B CG 1 ATOM 3682 C CD . LYS B 2 121 ? -12.175 73.822 -10.809 1.00 33.85 ? 121 LYS B CD 1 ATOM 3683 C CE . LYS B 2 121 ? -13.680 73.960 -10.793 1.00 45.59 ? 121 LYS B CE 1 ATOM 3684 N NZ . LYS B 2 121 ? -14.264 73.167 -9.676 1.00 50.75 ? 121 LYS B NZ 1 ATOM 3685 N N . VAL B 2 122 ? -8.535 74.063 -7.250 1.00 18.82 ? 122 VAL B N 1 ATOM 3686 C CA . VAL B 2 122 ? -8.529 73.403 -5.925 1.00 19.25 ? 122 VAL B CA 1 ATOM 3687 C C . VAL B 2 122 ? -7.899 74.337 -4.911 1.00 19.68 ? 122 VAL B C 1 ATOM 3688 O O . VAL B 2 122 ? -8.461 74.530 -3.823 1.00 20.48 ? 122 VAL B O 1 ATOM 3689 C CB . VAL B 2 122 ? -7.767 72.076 -5.939 1.00 17.96 ? 122 VAL B CB 1 ATOM 3690 C CG1 . VAL B 2 122 ? -7.622 71.526 -4.480 1.00 20.66 ? 122 VAL B CG1 1 ATOM 3691 C CG2 . VAL B 2 122 ? -8.542 71.067 -6.817 1.00 23.32 ? 122 VAL B CG2 1 ATOM 3692 N N . ARG B 2 123 ? -6.707 74.869 -5.213 1.00 19.37 ? 123 ARG B N 1 ATOM 3693 C CA . ARG B 2 123 ? -6.007 75.789 -4.288 1.00 17.71 ? 123 ARG B CA 1 ATOM 3694 C C . ARG B 2 123 ? -6.914 76.927 -3.749 1.00 21.21 ? 123 ARG B C 1 ATOM 3695 O O . ARG B 2 123 ? -6.919 77.236 -2.542 1.00 19.39 ? 123 ARG B O 1 ATOM 3696 C CB . ARG B 2 123 ? -4.774 76.436 -4.996 1.00 18.67 ? 123 ARG B CB 1 ATOM 3697 C CG . ARG B 2 123 ? -3.972 77.316 -4.048 1.00 22.41 ? 123 ARG B CG 1 ATOM 3698 C CD . ARG B 2 123 ? -2.684 77.727 -4.796 1.00 28.00 ? 123 ARG B CD 1 ATOM 3699 N NE . ARG B 2 123 ? -3.012 78.498 -5.996 1.00 30.25 ? 123 ARG B NE 1 ATOM 3700 C CZ . ARG B 2 123 ? -3.357 79.781 -5.961 1.00 27.83 ? 123 ARG B CZ 1 ATOM 3701 N NH1 . ARG B 2 123 ? -3.361 80.437 -4.812 1.00 32.52 ? 123 ARG B NH1 1 ATOM 3702 N NH2 . ARG B 2 123 ? -3.620 80.429 -7.117 1.00 32.29 ? 123 ARG B NH2 1 ATOM 3703 N N . LEU B 2 124 ? -7.706 77.536 -4.645 1.00 21.25 ? 124 LEU B N 1 ATOM 3704 C CA . LEU B 2 124 ? -8.505 78.708 -4.246 1.00 20.20 ? 124 LEU B CA 1 ATOM 3705 C C . LEU B 2 124 ? -9.788 78.321 -3.513 1.00 22.01 ? 124 LEU B C 1 ATOM 3706 O O . LEU B 2 124 ? -10.343 79.159 -2.807 1.00 24.17 ? 124 LEU B O 1 ATOM 3707 C CB . LEU B 2 124 ? -8.910 79.549 -5.464 1.00 18.31 ? 124 LEU B CB 1 ATOM 3708 C CG . LEU B 2 124 ? -7.646 80.197 -6.088 1.00 23.15 ? 124 LEU B CG 1 ATOM 3709 C CD1 . LEU B 2 124 ? -7.922 80.682 -7.505 1.00 25.62 ? 124 LEU B CD1 1 ATOM 3710 C CD2 . LEU B 2 124 ? -7.127 81.357 -5.176 1.00 30.13 ? 124 LEU B CD2 1 ATOM 3711 N N . GLN B 2 125 ? -10.244 77.063 -3.640 1.00 21.73 ? 125 GLN B N 1 ATOM 3712 C CA . GLN B 2 125 ? -11.337 76.583 -2.792 1.00 19.51 ? 125 GLN B CA 1 ATOM 3713 C C . GLN B 2 125 ? -10.816 76.290 -1.378 1.00 19.99 ? 125 GLN B C 1 ATOM 3714 O O . GLN B 2 125 ? -11.464 76.672 -0.389 1.00 23.22 ? 125 GLN B O 1 ATOM 3715 C CB . GLN B 2 125 ? -11.887 75.276 -3.330 1.00 23.05 ? 125 GLN B CB 1 ATOM 3716 C CG . GLN B 2 125 ? -12.777 75.400 -4.615 1.00 24.66 ? 125 GLN B CG 1 ATOM 3717 C CD . GLN B 2 125 ? -13.411 74.104 -4.940 1.00 26.23 ? 125 GLN B CD 1 ATOM 3718 O OE1 . GLN B 2 125 ? -14.535 73.843 -4.484 1.00 25.20 ? 125 GLN B OE1 1 ATOM 3719 N NE2 . GLN B 2 125 ? -12.667 73.216 -5.691 1.00 24.88 ? 125 GLN B NE2 1 ATOM 3720 N N . LEU B 2 126 ? -9.668 75.595 -1.279 1.00 18.08 ? 126 LEU B N 1 ATOM 3721 C CA . LEU B 2 126 ? -9.101 75.161 0.038 1.00 20.10 ? 126 LEU B CA 1 ATOM 3722 C C . LEU B 2 126 ? -8.556 76.308 0.883 1.00 25.58 ? 126 LEU B C 1 ATOM 3723 O O . LEU B 2 126 ? -8.692 76.288 2.112 1.00 21.66 ? 126 LEU B O 1 ATOM 3724 C CB . LEU B 2 126 ? -8.020 74.061 -0.146 1.00 20.46 ? 126 LEU B CB 1 ATOM 3725 C CG . LEU B 2 126 ? -8.589 72.819 -0.864 1.00 19.95 ? 126 LEU B CG 1 ATOM 3726 C CD1 . LEU B 2 126 ? -7.512 71.735 -0.854 1.00 19.89 ? 126 LEU B CD1 1 ATOM 3727 C CD2 . LEU B 2 126 ? -9.935 72.267 -0.273 1.00 22.34 ? 126 LEU B CD2 1 ATOM 3728 N N . ARG B 2 127 ? -7.940 77.298 0.226 1.00 21.23 ? 127 ARG B N 1 ATOM 3729 C CA . ARG B 2 127 ? -7.307 78.393 0.965 1.00 20.60 ? 127 ARG B CA 1 ATOM 3730 C C . ARG B 2 127 ? -6.420 77.851 2.089 1.00 23.68 ? 127 ARG B C 1 ATOM 3731 O O . ARG B 2 127 ? -5.674 76.888 1.883 1.00 25.18 ? 127 ARG B O 1 ATOM 3732 C CB . ARG B 2 127 ? -8.359 79.430 1.432 1.00 27.15 ? 127 ARG B CB 1 ATOM 3733 C CG . ARG B 2 127 ? -9.026 80.246 0.237 1.00 32.45 ? 127 ARG B CG 1 ATOM 3734 C CD . ARG B 2 127 ? -10.584 80.309 0.285 1.00 37.71 ? 127 ARG B CD 1 ATOM 3735 N NE . ARG B 2 127 ? -11.051 81.195 1.342 1.00 39.30 ? 127 ARG B NE 1 ATOM 3736 C CZ . ARG B 2 127 ? -12.327 81.411 1.659 1.00 48.67 ? 127 ARG B CZ 1 ATOM 3737 N NH1 . ARG B 2 127 ? -12.602 82.259 2.667 1.00 36.64 ? 127 ARG B NH1 1 ATOM 3738 N NH2 . ARG B 2 127 ? -13.319 80.797 0.989 1.00 36.60 ? 127 ARG B NH2 1 ATOM 3739 N N . ASP B 2 128 ? -6.545 78.400 3.285 1.00 22.35 ? 128 ASP B N 1 ATOM 3740 C CA . ASP B 2 128 ? -5.700 77.914 4.340 1.00 20.56 ? 128 ASP B CA 1 ATOM 3741 C C . ASP B 2 128 ? -6.273 76.729 5.165 1.00 26.28 ? 128 ASP B C 1 ATOM 3742 O O . ASP B 2 128 ? -5.734 76.411 6.245 1.00 24.43 ? 128 ASP B O 1 ATOM 3743 C CB . ASP B 2 128 ? -5.335 79.072 5.314 1.00 20.96 ? 128 ASP B CB 1 ATOM 3744 C CG . ASP B 2 128 ? -6.574 79.697 5.980 1.00 29.57 ? 128 ASP B CG 1 ATOM 3745 O OD1 . ASP B 2 128 ? -7.719 79.409 5.594 1.00 34.40 ? 128 ASP B OD1 1 ATOM 3746 O OD2 . ASP B 2 128 ? -6.421 80.564 6.864 1.00 33.38 ? 128 ASP B OD2 1 ATOM 3747 N N . ASN B 2 129 ? -7.291 76.083 4.640 1.00 22.55 ? 129 ASN B N 1 ATOM 3748 C CA . ASN B 2 129 ? -7.785 74.805 5.235 1.00 21.03 ? 129 ASN B CA 1 ATOM 3749 C C . ASN B 2 129 ? -6.924 73.649 4.833 1.00 23.95 ? 129 ASN B C 1 ATOM 3750 O O . ASN B 2 129 ? -7.130 72.539 5.310 1.00 22.35 ? 129 ASN B O 1 ATOM 3751 C CB . ASN B 2 129 ? -9.251 74.571 4.809 1.00 23.52 ? 129 ASN B CB 1 ATOM 3752 C CG . ASN B 2 129 ? -10.252 75.315 5.695 1.00 20.45 ? 129 ASN B CG 1 ATOM 3753 O OD1 . ASN B 2 129 ? -9.885 76.152 6.547 1.00 22.30 ? 129 ASN B OD1 1 ATOM 3754 N ND2 . ASN B 2 129 ? -11.542 75.095 5.427 1.00 20.59 ? 129 ASN B ND2 1 ATOM 3755 N N . ALA B 2 130 ? -5.953 73.861 3.929 1.00 20.38 ? 130 ALA B N 1 ATOM 3756 C CA . ALA B 2 130 ? -5.001 72.839 3.614 1.00 18.04 ? 130 ALA B CA 1 ATOM 3757 C C . ALA B 2 130 ? -3.647 73.492 3.304 1.00 20.88 ? 130 ALA B C 1 ATOM 3758 O O . ALA B 2 130 ? -3.593 74.701 3.084 1.00 23.62 ? 130 ALA B O 1 ATOM 3759 C CB . ALA B 2 130 ? -5.473 72.044 2.348 1.00 19.65 ? 130 ALA B CB 1 ATOM 3760 N N . LYS B 2 131 ? -2.622 72.678 3.415 1.00 20.12 ? 131 LYS B N 1 ATOM 3761 C CA . LYS B 2 131 ? -1.201 73.037 3.130 1.00 24.93 ? 131 LYS B CA 1 ATOM 3762 C C . LYS B 2 131 ? -0.825 72.659 1.670 1.00 25.38 ? 131 LYS B C 1 ATOM 3763 O O . LYS B 2 131 ? -0.958 71.527 1.248 1.00 23.41 ? 131 LYS B O 1 ATOM 3764 C CB . LYS B 2 131 ? -0.321 72.248 4.139 1.00 28.67 ? 131 LYS B CB 1 ATOM 3765 C CG . LYS B 2 131 ? 1.139 72.633 4.155 1.00 37.10 ? 131 LYS B CG 1 ATOM 3766 C CD . LYS B 2 131 ? 1.754 72.231 5.509 1.00 41.39 ? 131 LYS B CD 1 ATOM 3767 C CE . LYS B 2 131 ? 3.275 72.601 5.639 1.00 45.15 ? 131 LYS B CE 1 ATOM 3768 N NZ . LYS B 2 131 ? 4.048 71.982 4.485 1.00 42.78 ? 131 LYS B NZ 1 ATOM 3769 N N . GLU B 2 132 ? -0.277 73.607 0.911 1.00 23.67 ? 132 GLU B N 1 ATOM 3770 C CA . GLU B 2 132 ? 0.239 73.262 -0.382 1.00 24.04 ? 132 GLU B CA 1 ATOM 3771 C C . GLU B 2 132 ? 1.597 72.579 -0.266 1.00 28.64 ? 132 GLU B C 1 ATOM 3772 O O . GLU B 2 132 ? 2.544 73.178 0.248 1.00 31.22 ? 132 GLU B O 1 ATOM 3773 C CB . GLU B 2 132 ? 0.359 74.605 -1.097 1.00 29.71 ? 132 GLU B CB 1 ATOM 3774 C CG . GLU B 2 132 ? 0.713 74.587 -2.459 1.00 33.31 ? 132 GLU B CG 1 ATOM 3775 C CD . GLU B 2 132 ? 0.398 75.929 -3.104 1.00 34.67 ? 132 GLU B CD 1 ATOM 3776 O OE1 . GLU B 2 132 ? 0.243 75.936 -4.325 1.00 26.09 ? 132 GLU B OE1 1 ATOM 3777 O OE2 . GLU B 2 132 ? 0.303 76.975 -2.406 1.00 42.15 ? 132 GLU B OE2 1 ATOM 3778 N N . LEU B 2 133 ? 1.738 71.372 -0.793 1.00 20.27 ? 133 LEU B N 1 ATOM 3779 C CA . LEU B 2 133 ? 2.984 70.597 -0.584 1.00 21.57 ? 133 LEU B CA 1 ATOM 3780 C C . LEU B 2 133 ? 4.066 70.898 -1.620 1.00 23.41 ? 133 LEU B C 1 ATOM 3781 O O . LEU B 2 133 ? 5.205 70.537 -1.422 1.00 28.56 ? 133 LEU B O 1 ATOM 3782 C CB . LEU B 2 133 ? 2.717 69.101 -0.506 1.00 22.21 ? 133 LEU B CB 1 ATOM 3783 C CG . LEU B 2 133 ? 1.767 68.708 0.626 1.00 25.29 ? 133 LEU B CG 1 ATOM 3784 C CD1 . LEU B 2 133 ? 1.547 67.201 0.571 1.00 28.21 ? 133 LEU B CD1 1 ATOM 3785 C CD2 . LEU B 2 133 ? 2.313 69.132 2.052 1.00 28.60 ? 133 LEU B CD2 1 ATOM 3786 N N . GLY B 2 134 ? 3.657 71.481 -2.729 1.00 24.28 ? 134 GLY B N 1 ATOM 3787 C CA . GLY B 2 134 ? 4.585 71.979 -3.741 1.00 31.31 ? 134 GLY B CA 1 ATOM 3788 C C . GLY B 2 134 ? 4.755 71.028 -4.912 1.00 34.97 ? 134 GLY B C 1 ATOM 3789 O O . GLY B 2 134 ? 5.549 71.282 -5.829 1.00 29.36 ? 134 GLY B O 1 ATOM 3790 N N . ASN B 2 135 ? 4.006 69.931 -4.907 1.00 23.38 ? 135 ASN B N 1 ATOM 3791 C CA . ASN B 2 135 ? 4.231 68.884 -5.898 1.00 22.88 ? 135 ASN B CA 1 ATOM 3792 C C . ASN B 2 135 ? 2.914 68.548 -6.621 1.00 19.85 ? 135 ASN B C 1 ATOM 3793 O O . ASN B 2 135 ? 2.793 67.538 -7.284 1.00 22.77 ? 135 ASN B O 1 ATOM 3794 C CB . ASN B 2 135 ? 4.712 67.603 -5.172 1.00 26.35 ? 135 ASN B CB 1 ATOM 3795 C CG . ASN B 2 135 ? 3.701 67.123 -4.152 1.00 26.15 ? 135 ASN B CG 1 ATOM 3796 O OD1 . ASN B 2 135 ? 2.770 67.825 -3.871 1.00 25.46 ? 135 ASN B OD1 1 ATOM 3797 N ND2 . ASN B 2 135 ? 3.922 65.944 -3.536 1.00 29.46 ? 135 ASN B ND2 1 ATOM 3798 N N . GLY B 2 136 ? 1.942 69.411 -6.458 1.00 21.45 ? 136 GLY B N 1 ATOM 3799 C CA . GLY B 2 136 ? 0.617 69.222 -7.031 1.00 17.78 ? 136 GLY B CA 1 ATOM 3800 C C . GLY B 2 136 ? -0.369 68.706 -5.992 1.00 20.56 ? 136 GLY B C 1 ATOM 3801 O O . GLY B 2 136 ? -1.572 68.581 -6.257 1.00 20.87 ? 136 GLY B O 1 ATOM 3802 N N . CYS B 2 137 ? 0.105 68.437 -4.775 1.00 17.98 ? 137 CYS B N 1 ATOM 3803 C CA . CYS B 2 137 ? -0.750 67.915 -3.700 1.00 18.77 ? 137 CYS B CA 1 ATOM 3804 C C . CYS B 2 137 ? -1.023 68.930 -2.577 1.00 18.98 ? 137 CYS B C 1 ATOM 3805 O O . CYS B 2 137 ? -0.218 69.844 -2.332 1.00 20.45 ? 137 CYS B O 1 ATOM 3806 C CB . CYS B 2 137 ? -0.136 66.692 -3.033 1.00 22.82 ? 137 CYS B CB 1 ATOM 3807 S SG . CYS B 2 137 ? 0.217 65.366 -4.209 1.00 28.30 ? 137 CYS B SG 1 ATOM 3808 N N . PHE B 2 138 ? -2.149 68.723 -1.893 1.00 18.07 ? 138 PHE B N 1 ATOM 3809 C CA . PHE B 2 138 ? -2.582 69.531 -0.763 1.00 19.25 ? 138 PHE B CA 1 ATOM 3810 C C . PHE B 2 138 ? -2.744 68.586 0.413 1.00 22.84 ? 138 PHE B C 1 ATOM 3811 O O . PHE B 2 138 ? -3.359 67.546 0.254 1.00 21.60 ? 138 PHE B O 1 ATOM 3812 C CB . PHE B 2 138 ? -3.918 70.243 -1.051 1.00 21.34 ? 138 PHE B CB 1 ATOM 3813 C CG . PHE B 2 138 ? -3.841 71.242 -2.182 1.00 20.76 ? 138 PHE B CG 1 ATOM 3814 C CD1 . PHE B 2 138 ? -4.019 70.848 -3.465 1.00 19.46 ? 138 PHE B CD1 1 ATOM 3815 C CD2 . PHE B 2 138 ? -3.569 72.575 -1.910 1.00 22.15 ? 138 PHE B CD2 1 ATOM 3816 C CE1 . PHE B 2 138 ? -3.909 71.752 -4.524 1.00 28.42 ? 138 PHE B CE1 1 ATOM 3817 C CE2 . PHE B 2 138 ? -3.444 73.520 -2.973 1.00 22.58 ? 138 PHE B CE2 1 ATOM 3818 C CZ . PHE B 2 138 ? -3.608 73.084 -4.263 1.00 22.31 ? 138 PHE B CZ 1 ATOM 3819 N N . GLU B 2 139 ? -2.287 68.991 1.607 1.00 18.16 ? 139 GLU B N 1 ATOM 3820 C CA . GLU B 2 139 ? -2.547 68.164 2.794 1.00 22.01 ? 139 GLU B CA 1 ATOM 3821 C C . GLU B 2 139 ? -3.538 68.899 3.662 1.00 23.60 ? 139 GLU B C 1 ATOM 3822 O O . GLU B 2 139 ? -3.303 70.014 4.082 1.00 22.21 ? 139 GLU B O 1 ATOM 3823 C CB . GLU B 2 139 ? -1.230 67.909 3.516 1.00 23.55 ? 139 GLU B CB 1 ATOM 3824 C CG . GLU B 2 139 ? -1.428 66.986 4.791 1.00 26.45 ? 139 GLU B CG 1 ATOM 3825 C CD . GLU B 2 139 ? -0.125 66.778 5.559 1.00 48.77 ? 139 GLU B CD 1 ATOM 3826 O OE1 . GLU B 2 139 ? 0.880 67.449 5.254 1.00 45.31 ? 139 GLU B OE1 1 ATOM 3827 O OE2 . GLU B 2 139 ? -0.108 65.943 6.474 1.00 44.07 ? 139 GLU B OE2 1 ATOM 3828 N N . PHE B 2 140 ? -4.704 68.301 3.891 1.00 20.01 ? 140 PHE B N 1 ATOM 3829 C CA . PHE B 2 140 ? -5.747 68.976 4.610 1.00 20.77 ? 140 PHE B CA 1 ATOM 3830 C C . PHE B 2 140 ? -5.415 69.138 6.126 1.00 21.21 ? 140 PHE B C 1 ATOM 3831 O O . PHE B 2 140 ? -4.795 68.244 6.723 1.00 26.53 ? 140 PHE B O 1 ATOM 3832 C CB . PHE B 2 140 ? -6.992 68.150 4.522 1.00 19.95 ? 140 PHE B CB 1 ATOM 3833 C CG . PHE B 2 140 ? -7.666 68.216 3.163 1.00 19.01 ? 140 PHE B CG 1 ATOM 3834 C CD1 . PHE B 2 140 ? -7.296 67.306 2.169 1.00 21.56 ? 140 PHE B CD1 1 ATOM 3835 C CD2 . PHE B 2 140 ? -8.639 69.158 2.901 1.00 21.50 ? 140 PHE B CD2 1 ATOM 3836 C CE1 . PHE B 2 140 ? -7.926 67.342 0.922 1.00 22.53 ? 140 PHE B CE1 1 ATOM 3837 C CE2 . PHE B 2 140 ? -9.257 69.201 1.643 1.00 22.53 ? 140 PHE B CE2 1 ATOM 3838 C CZ . PHE B 2 140 ? -8.906 68.311 0.684 1.00 23.30 ? 140 PHE B CZ 1 ATOM 3839 N N . TYR B 2 141 ? -5.843 70.279 6.701 1.00 20.80 ? 141 TYR B N 1 ATOM 3840 C CA . TYR B 2 141 ? -5.749 70.491 8.158 1.00 23.26 ? 141 TYR B CA 1 ATOM 3841 C C . TYR B 2 141 ? -7.027 69.949 8.864 1.00 28.95 ? 141 TYR B C 1 ATOM 3842 O O . TYR B 2 141 ? -7.194 70.055 10.096 1.00 30.25 ? 141 TYR B O 1 ATOM 3843 C CB . TYR B 2 141 ? -5.685 71.989 8.360 1.00 20.95 ? 141 TYR B CB 1 ATOM 3844 C CG . TYR B 2 141 ? -4.340 72.582 8.035 1.00 20.47 ? 141 TYR B CG 1 ATOM 3845 C CD1 . TYR B 2 141 ? -4.244 73.633 7.123 1.00 21.81 ? 141 TYR B CD1 1 ATOM 3846 C CD2 . TYR B 2 141 ? -3.180 72.083 8.612 1.00 23.23 ? 141 TYR B CD2 1 ATOM 3847 C CE1 . TYR B 2 141 ? -3.003 74.212 6.857 1.00 24.21 ? 141 TYR B CE1 1 ATOM 3848 C CE2 . TYR B 2 141 ? -1.914 72.675 8.347 1.00 30.35 ? 141 TYR B CE2 1 ATOM 3849 C CZ . TYR B 2 141 ? -1.863 73.723 7.474 1.00 27.03 ? 141 TYR B CZ 1 ATOM 3850 O OH . TYR B 2 141 ? -0.658 74.319 7.195 1.00 29.04 ? 141 TYR B OH 1 ATOM 3851 N N . HIS B 2 142 ? -7.961 69.413 8.108 1.00 21.94 ? 142 HIS B N 1 ATOM 3852 C CA . HIS B 2 142 ? -9.199 68.868 8.715 1.00 23.19 ? 142 HIS B CA 1 ATOM 3853 C C . HIS B 2 142 ? -9.422 67.517 8.094 1.00 30.12 ? 142 HIS B C 1 ATOM 3854 O O . HIS B 2 142 ? -8.846 67.227 7.032 1.00 23.48 ? 142 HIS B O 1 ATOM 3855 C CB . HIS B 2 142 ? -10.396 69.756 8.427 1.00 25.68 ? 142 HIS B CB 1 ATOM 3856 C CG . HIS B 2 142 ? -10.712 69.957 6.963 1.00 24.32 ? 142 HIS B CG 1 ATOM 3857 N ND1 . HIS B 2 142 ? -11.523 69.108 6.235 1.00 24.56 ? 142 HIS B ND1 1 ATOM 3858 C CD2 . HIS B 2 142 ? -10.417 70.993 6.127 1.00 21.70 ? 142 HIS B CD2 1 ATOM 3859 C CE1 . HIS B 2 142 ? -11.677 69.594 5.002 1.00 25.09 ? 142 HIS B CE1 1 ATOM 3860 N NE2 . HIS B 2 142 ? -11.034 70.748 4.922 1.00 21.96 ? 142 HIS B NE2 1 ATOM 3861 N N . LYS B 2 143 ? -10.225 66.657 8.728 1.00 26.64 ? 143 LYS B N 1 ATOM 3862 C CA . LYS B 2 143 ? -10.525 65.394 8.069 1.00 23.23 ? 143 LYS B CA 1 ATOM 3863 C C . LYS B 2 143 ? -11.405 65.645 6.861 1.00 20.81 ? 143 LYS B C 1 ATOM 3864 O O . LYS B 2 143 ? -12.365 66.423 6.901 1.00 25.24 ? 143 LYS B O 1 ATOM 3865 C CB . LYS B 2 143 ? -11.266 64.418 9.034 1.00 29.13 ? 143 LYS B CB 1 ATOM 3866 C CG . LYS B 2 143 ? -10.489 64.178 10.310 1.00 40.42 ? 143 LYS B CG 1 ATOM 3867 C CD . LYS B 2 143 ? -9.230 63.397 10.090 1.00 51.79 ? 143 LYS B CD 1 ATOM 3868 C CE . LYS B 2 143 ? -8.631 62.985 11.439 1.00 72.61 ? 143 LYS B CE 1 ATOM 3869 N NZ . LYS B 2 143 ? -9.664 62.358 12.337 1.00 79.80 ? 143 LYS B NZ 1 ATOM 3870 N N . CYS B 2 144 ? -11.107 64.946 5.770 1.00 24.82 ? 144 CYS B N 1 ATOM 3871 C CA . CYS B 2 144 ? -11.846 65.187 4.529 1.00 25.99 ? 144 CYS B CA 1 ATOM 3872 C C . CYS B 2 144 ? -12.278 63.846 3.958 1.00 26.52 ? 144 CYS B C 1 ATOM 3873 O O . CYS B 2 144 ? -11.501 63.181 3.301 1.00 24.70 ? 144 CYS B O 1 ATOM 3874 C CB . CYS B 2 144 ? -10.959 65.941 3.461 1.00 28.38 ? 144 CYS B CB 1 ATOM 3875 S SG . CYS B 2 144 ? -11.869 66.462 1.961 1.00 27.74 ? 144 CYS B SG 1 ATOM 3876 N N . ASP B 2 145 ? -13.523 63.459 4.253 1.00 23.80 ? 145 ASP B N 1 ATOM 3877 C CA . ASP B 2 145 ? -13.999 62.106 3.866 1.00 32.08 ? 145 ASP B CA 1 ATOM 3878 C C . ASP B 2 145 ? -14.380 62.063 2.386 1.00 34.67 ? 145 ASP B C 1 ATOM 3879 O O . ASP B 2 145 ? -14.203 63.039 1.687 1.00 26.87 ? 145 ASP B O 1 ATOM 3880 C CB . ASP B 2 145 ? -15.172 61.656 4.778 1.00 29.32 ? 145 ASP B CB 1 ATOM 3881 C CG . ASP B 2 145 ? -16.427 62.514 4.642 1.00 36.84 ? 145 ASP B CG 1 ATOM 3882 O OD1 . ASP B 2 145 ? -17.320 62.400 5.539 1.00 42.39 ? 145 ASP B OD1 1 ATOM 3883 O OD2 . ASP B 2 145 ? -16.597 63.291 3.677 1.00 32.94 ? 145 ASP B OD2 1 ATOM 3884 N N . ASN B 2 146 ? -14.908 60.946 1.877 1.00 28.44 ? 146 ASN B N 1 ATOM 3885 C CA . ASN B 2 146 ? -15.203 60.919 0.449 1.00 29.58 ? 146 ASN B CA 1 ATOM 3886 C C . ASN B 2 146 ? -16.175 61.974 -0.012 1.00 33.03 ? 146 ASN B C 1 ATOM 3887 O O . ASN B 2 146 ? -16.021 62.494 -1.099 1.00 28.47 ? 146 ASN B O 1 ATOM 3888 C CB . ASN B 2 146 ? -15.712 59.523 -0.011 1.00 31.47 ? 146 ASN B CB 1 ATOM 3889 C CG . ASN B 2 146 ? -14.674 58.435 0.165 1.00 36.53 ? 146 ASN B CG 1 ATOM 3890 O OD1 . ASN B 2 146 ? -13.469 58.694 0.177 1.00 33.02 ? 146 ASN B OD1 1 ATOM 3891 N ND2 . ASN B 2 146 ? -15.144 57.171 0.230 1.00 35.15 ? 146 ASN B ND2 1 ATOM 3892 N N . GLU B 2 147 ? -17.209 62.306 0.759 1.00 28.60 ? 147 GLU B N 1 ATOM 3893 C CA . GLU B 2 147 ? -18.129 63.320 0.243 1.00 32.50 ? 147 GLU B CA 1 ATOM 3894 C C . GLU B 2 147 ? -17.418 64.676 0.194 1.00 29.12 ? 147 GLU B C 1 ATOM 3895 O O . GLU B 2 147 ? -17.656 65.489 -0.691 1.00 29.42 ? 147 GLU B O 1 ATOM 3896 C CB . GLU B 2 147 ? -19.393 63.449 1.096 1.00 40.34 ? 147 GLU B CB 1 ATOM 3897 C CG . GLU B 2 147 ? -20.461 62.414 0.748 1.00 50.88 ? 147 GLU B CG 1 ATOM 3898 C CD . GLU B 2 147 ? -21.695 62.495 1.656 1.00 76.90 ? 147 GLU B CD 1 ATOM 3899 O OE1 . GLU B 2 147 ? -22.119 63.621 2.020 1.00 67.97 ? 147 GLU B OE1 1 ATOM 3900 O OE2 . GLU B 2 147 ? -22.240 61.425 2.013 1.00 93.30 ? 147 GLU B OE2 1 ATOM 3901 N N . CYS B 2 148 ? -16.554 64.915 1.169 1.00 32.50 ? 148 CYS B N 1 ATOM 3902 C CA . CYS B 2 148 ? -15.785 66.179 1.188 1.00 27.57 ? 148 CYS B CA 1 ATOM 3903 C C . CYS B 2 148 ? -14.825 66.232 -0.021 1.00 24.67 ? 148 CYS B C 1 ATOM 3904 O O . CYS B 2 148 ? -14.779 67.228 -0.739 1.00 28.25 ? 148 CYS B O 1 ATOM 3905 C CB . CYS B 2 148 ? -15.042 66.277 2.520 1.00 26.38 ? 148 CYS B CB 1 ATOM 3906 S SG . CYS B 2 148 ? -13.688 67.561 2.608 1.00 35.27 ? 148 CYS B SG 1 ATOM 3907 N N . MET B 2 149 ? -14.123 65.147 -0.276 1.00 23.22 ? 149 MET B N 1 ATOM 3908 C CA . MET B 2 149 ? -13.268 65.091 -1.470 1.00 25.52 ? 149 MET B CA 1 ATOM 3909 C C . MET B 2 149 ? -14.108 65.350 -2.708 1.00 33.71 ? 149 MET B C 1 ATOM 3910 O O . MET B 2 149 ? -13.715 66.063 -3.576 1.00 22.24 ? 149 MET B O 1 ATOM 3911 C CB . MET B 2 149 ? -12.600 63.733 -1.641 1.00 23.40 ? 149 MET B CB 1 ATOM 3912 C CG . MET B 2 149 ? -11.622 63.328 -0.550 1.00 25.06 ? 149 MET B CG 1 ATOM 3913 S SD . MET B 2 149 ? -10.136 64.391 -0.638 1.00 25.97 ? 149 MET B SD 1 ATOM 3914 C CE . MET B 2 149 ? -9.148 63.653 0.683 1.00 29.49 ? 149 MET B CE 1 ATOM 3915 N N . GLU B 2 150 ? -15.304 64.791 -2.787 1.00 27.03 ? 150 GLU B N 1 ATOM 3916 C CA . GLU B 2 150 ? -16.070 65.013 -4.001 1.00 27.08 ? 150 GLU B CA 1 ATOM 3917 C C . GLU B 2 150 ? -16.486 66.487 -4.098 1.00 29.79 ? 150 GLU B C 1 ATOM 3918 O O . GLU B 2 150 ? -16.549 67.042 -5.214 1.00 25.85 ? 150 GLU B O 1 ATOM 3919 C CB . GLU B 2 150 ? -17.326 64.111 -3.985 1.00 29.41 ? 150 GLU B CB 1 ATOM 3920 C CG . GLU B 2 150 ? -18.211 64.391 -5.199 1.00 33.69 ? 150 GLU B CG 1 ATOM 3921 C CD . GLU B 2 150 ? -17.490 64.114 -6.542 1.00 37.63 ? 150 GLU B CD 1 ATOM 3922 O OE1 . GLU B 2 150 ? -17.930 64.673 -7.559 1.00 42.98 ? 150 GLU B OE1 1 ATOM 3923 O OE2 . GLU B 2 150 ? -16.506 63.336 -6.589 1.00 41.36 ? 150 GLU B OE2 1 ATOM 3924 N N . SER B 2 151 ? -16.727 67.148 -2.953 1.00 26.08 ? 151 SER B N 1 ATOM 3925 C CA . SER B 2 151 ? -17.068 68.557 -3.021 1.00 26.81 ? 151 SER B CA 1 ATOM 3926 C C . SER B 2 151 ? -15.875 69.377 -3.569 1.00 27.75 ? 151 SER B C 1 ATOM 3927 O O . SER B 2 151 ? -16.084 70.377 -4.221 1.00 25.36 ? 151 SER B O 1 ATOM 3928 C CB . SER B 2 151 ? -17.527 69.129 -1.673 1.00 28.35 ? 151 SER B CB 1 ATOM 3929 O OG . SER B 2 151 ? -16.426 69.388 -0.809 1.00 25.57 ? 151 SER B OG 1 ATOM 3930 N N . VAL B 2 152 ? -14.653 68.956 -3.262 1.00 22.84 ? 152 VAL B N 1 ATOM 3931 C CA . VAL B 2 152 ? -13.467 69.637 -3.842 1.00 20.60 ? 152 VAL B CA 1 ATOM 3932 C C . VAL B 2 152 ? -13.411 69.423 -5.353 1.00 22.14 ? 152 VAL B C 1 ATOM 3933 O O . VAL B 2 152 ? -13.206 70.356 -6.122 1.00 23.56 ? 152 VAL B O 1 ATOM 3934 C CB . VAL B 2 152 ? -12.164 69.161 -3.172 1.00 20.88 ? 152 VAL B CB 1 ATOM 3935 C CG1 . VAL B 2 152 ? -10.961 69.858 -3.902 1.00 20.16 ? 152 VAL B CG1 1 ATOM 3936 C CG2 . VAL B 2 152 ? -12.188 69.524 -1.672 1.00 22.25 ? 152 VAL B CG2 1 ATOM 3937 N N . ARG B 2 153 ? -13.607 68.193 -5.766 1.00 23.42 ? 153 ARG B N 1 ATOM 3938 C CA . ARG B 2 153 ? -13.511 67.893 -7.176 1.00 24.27 ? 153 ARG B CA 1 ATOM 3939 C C . ARG B 2 153 ? -14.645 68.546 -8.001 1.00 26.45 ? 153 ARG B C 1 ATOM 3940 O O . ARG B 2 153 ? -14.468 68.828 -9.179 1.00 26.00 ? 153 ARG B O 1 ATOM 3941 C CB . ARG B 2 153 ? -13.527 66.361 -7.407 1.00 21.87 ? 153 ARG B CB 1 ATOM 3942 C CG . ARG B 2 153 ? -12.331 65.603 -6.805 1.00 20.92 ? 153 ARG B CG 1 ATOM 3943 C CD . ARG B 2 153 ? -12.286 64.091 -7.232 1.00 24.08 ? 153 ARG B CD 1 ATOM 3944 N NE . ARG B 2 153 ? -13.455 63.423 -6.621 1.00 31.32 ? 153 ARG B NE 1 ATOM 3945 C CZ . ARG B 2 153 ? -13.393 62.549 -5.613 1.00 33.46 ? 153 ARG B CZ 1 ATOM 3946 N NH1 . ARG B 2 153 ? -12.241 62.111 -5.112 1.00 30.27 ? 153 ARG B NH1 1 ATOM 3947 N NH2 . ARG B 2 153 ? -14.527 62.090 -5.096 1.00 38.57 ? 153 ARG B NH2 1 ATOM 3948 N N . ASN B 2 154 ? -15.805 68.775 -7.389 1.00 23.06 ? 154 ASN B N 1 ATOM 3949 C CA . ASN B 2 154 ? -16.896 69.395 -8.153 1.00 25.61 ? 154 ASN B CA 1 ATOM 3950 C C . ASN B 2 154 ? -17.139 70.892 -7.911 1.00 37.86 ? 154 ASN B C 1 ATOM 3951 O O . ASN B 2 154 ? -18.109 71.476 -8.408 1.00 30.75 ? 154 ASN B O 1 ATOM 3952 C CB . ASN B 2 154 ? -18.196 68.565 -8.092 1.00 35.13 ? 154 ASN B CB 1 ATOM 3953 C CG . ASN B 2 154 ? -18.941 68.691 -6.765 1.00 37.07 ? 154 ASN B CG 1 ATOM 3954 O OD1 . ASN B 2 154 ? -18.660 69.575 -5.949 1.00 31.04 ? 154 ASN B OD1 1 ATOM 3955 N ND2 . ASN B 2 154 ? -19.913 67.767 -6.549 1.00 42.48 ? 154 ASN B ND2 1 ATOM 3956 N N . GLY B 2 155 ? -16.225 71.529 -7.193 1.00 27.44 ? 155 GLY B N 1 ATOM 3957 C CA . GLY B 2 155 ? -16.239 72.973 -7.009 1.00 27.03 ? 155 GLY B CA 1 ATOM 3958 C C . GLY B 2 155 ? -17.269 73.458 -5.994 1.00 26.46 ? 155 GLY B C 1 ATOM 3959 O O . GLY B 2 155 ? -17.697 74.584 -6.076 1.00 31.14 ? 155 GLY B O 1 ATOM 3960 N N . THR B 2 156 ? -17.645 72.632 -5.032 1.00 26.69 ? 156 THR B N 1 ATOM 3961 C CA . THR B 2 156 ? -18.632 73.038 -4.035 1.00 33.92 ? 156 THR B CA 1 ATOM 3962 C C . THR B 2 156 ? -18.104 72.936 -2.616 1.00 32.70 ? 156 THR B C 1 ATOM 3963 O O . THR B 2 156 ? -18.882 73.019 -1.646 1.00 32.73 ? 156 THR B O 1 ATOM 3964 C CB . THR B 2 156 ? -19.930 72.255 -4.152 1.00 27.05 ? 156 THR B CB 1 ATOM 3965 O OG1 . THR B 2 156 ? -19.710 70.873 -3.883 1.00 32.32 ? 156 THR B OG1 1 ATOM 3966 C CG2 . THR B 2 156 ? -20.507 72.461 -5.596 1.00 34.18 ? 156 THR B CG2 1 ATOM 3967 N N . TYR B 2 157 ? -16.780 72.807 -2.498 1.00 26.59 ? 157 TYR B N 1 ATOM 3968 C CA . TYR B 2 157 ? -16.139 72.699 -1.204 1.00 23.34 ? 157 TYR B CA 1 ATOM 3969 C C . TYR B 2 157 ? -16.612 73.821 -0.323 1.00 27.74 ? 157 TYR B C 1 ATOM 3970 O O . TYR B 2 157 ? -16.659 74.958 -0.751 1.00 27.95 ? 157 TYR B O 1 ATOM 3971 C CB . TYR B 2 157 ? -14.602 72.732 -1.339 1.00 21.50 ? 157 TYR B CB 1 ATOM 3972 C CG . TYR B 2 157 ? -13.830 72.741 -0.045 1.00 23.88 ? 157 TYR B CG 1 ATOM 3973 C CD1 . TYR B 2 157 ? -13.310 73.921 0.431 1.00 20.15 ? 157 TYR B CD1 1 ATOM 3974 C CD2 . TYR B 2 157 ? -13.680 71.586 0.734 1.00 22.75 ? 157 TYR B CD2 1 ATOM 3975 C CE1 . TYR B 2 157 ? -12.607 73.973 1.609 1.00 21.21 ? 157 TYR B CE1 1 ATOM 3976 C CE2 . TYR B 2 157 ? -12.982 71.650 1.982 1.00 21.70 ? 157 TYR B CE2 1 ATOM 3977 C CZ . TYR B 2 157 ? -12.436 72.837 2.358 1.00 23.10 ? 157 TYR B CZ 1 ATOM 3978 O OH . TYR B 2 157 ? -11.720 72.931 3.512 1.00 22.68 ? 157 TYR B OH 1 ATOM 3979 N N . ASP B 2 158 ? -16.915 73.494 0.927 1.00 27.51 ? 158 ASP B N 1 ATOM 3980 C CA . ASP B 2 158 ? -17.525 74.473 1.815 1.00 29.51 ? 158 ASP B CA 1 ATOM 3981 C C . ASP B 2 158 ? -16.500 74.897 2.862 1.00 28.39 ? 158 ASP B C 1 ATOM 3982 O O . ASP B 2 158 ? -16.363 74.250 3.916 1.00 27.35 ? 158 ASP B O 1 ATOM 3983 C CB . ASP B 2 158 ? -18.756 73.807 2.475 1.00 36.28 ? 158 ASP B CB 1 ATOM 3984 C CG . ASP B 2 158 ? -19.494 74.718 3.480 1.00 43.97 ? 158 ASP B CG 1 ATOM 3985 O OD1 . ASP B 2 158 ? -18.998 75.807 3.867 1.00 32.87 ? 158 ASP B OD1 1 ATOM 3986 O OD2 . ASP B 2 158 ? -20.592 74.293 3.918 1.00 37.26 ? 158 ASP B OD2 1 ATOM 3987 N N . TYR B 2 159 ? -15.751 75.963 2.562 1.00 25.92 ? 159 TYR B N 1 ATOM 3988 C CA . TYR B 2 159 ? -14.676 76.378 3.428 1.00 22.51 ? 159 TYR B CA 1 ATOM 3989 C C . TYR B 2 159 ? -15.142 76.687 4.880 1.00 23.52 ? 159 TYR B C 1 ATOM 3990 O O . TYR B 2 159 ? -14.476 76.264 5.835 1.00 23.78 ? 159 TYR B O 1 ATOM 3991 C CB . TYR B 2 159 ? -13.916 77.560 2.805 1.00 25.22 ? 159 TYR B CB 1 ATOM 3992 C CG . TYR B 2 159 ? -12.924 78.220 3.702 1.00 24.45 ? 159 TYR B CG 1 ATOM 3993 C CD1 . TYR B 2 159 ? -13.311 79.246 4.603 1.00 24.85 ? 159 TYR B CD1 1 ATOM 3994 C CD2 . TYR B 2 159 ? -11.575 77.899 3.620 1.00 24.48 ? 159 TYR B CD2 1 ATOM 3995 C CE1 . TYR B 2 159 ? -12.380 79.860 5.398 1.00 27.33 ? 159 TYR B CE1 1 ATOM 3996 C CE2 . TYR B 2 159 ? -10.666 78.497 4.425 1.00 24.31 ? 159 TYR B CE2 1 ATOM 3997 C CZ . TYR B 2 159 ? -11.062 79.501 5.280 1.00 24.14 ? 159 TYR B CZ 1 ATOM 3998 O OH . TYR B 2 159 ? -10.138 80.068 6.053 1.00 25.77 ? 159 TYR B OH 1 ATOM 3999 N N . PRO B 2 160 ? -16.234 77.473 5.030 1.00 26.18 ? 160 PRO B N 1 ATOM 4000 C CA . PRO B 2 160 ? -16.685 77.789 6.392 1.00 28.15 ? 160 PRO B CA 1 ATOM 4001 C C . PRO B 2 160 ? -16.995 76.551 7.251 1.00 27.86 ? 160 PRO B C 1 ATOM 4002 O O . PRO B 2 160 ? -16.748 76.583 8.476 1.00 28.08 ? 160 PRO B O 1 ATOM 4003 C CB . PRO B 2 160 ? -17.974 78.593 6.147 1.00 33.89 ? 160 PRO B CB 1 ATOM 4004 C CG . PRO B 2 160 ? -17.700 79.315 4.866 1.00 32.11 ? 160 PRO B CG 1 ATOM 4005 C CD . PRO B 2 160 ? -17.044 78.200 4.026 1.00 26.56 ? 160 PRO B CD 1 ATOM 4006 N N . GLN B 2 161 ? -17.463 75.476 6.625 1.00 27.96 ? 161 GLN B N 1 ATOM 4007 C CA . GLN B 2 161 ? -17.803 74.249 7.352 1.00 30.50 ? 161 GLN B CA 1 ATOM 4008 C C . GLN B 2 161 ? -16.613 73.686 8.106 1.00 29.13 ? 161 GLN B C 1 ATOM 4009 O O . GLN B 2 161 ? -16.775 73.173 9.247 1.00 26.17 ? 161 GLN B O 1 ATOM 4010 C CB . GLN B 2 161 ? -18.387 73.206 6.394 1.00 26.85 ? 161 GLN B CB 1 ATOM 4011 C CG . GLN B 2 161 ? -18.563 71.799 7.019 1.00 29.61 ? 161 GLN B CG 1 ATOM 4012 C CD . GLN B 2 161 ? -19.707 71.740 8.074 1.00 58.86 ? 161 GLN B CD 1 ATOM 4013 O OE1 . GLN B 2 161 ? -20.562 72.640 8.155 1.00 61.25 ? 161 GLN B OE1 1 ATOM 4014 N NE2 . GLN B 2 161 ? -19.719 70.672 8.875 1.00 44.87 ? 161 GLN B NE2 1 ATOM 4015 N N . TYR B 2 162 ? -15.413 73.810 7.513 1.00 22.24 ? 162 TYR B N 1 ATOM 4016 C CA . TYR B 2 162 ? -14.223 73.173 8.060 1.00 23.00 ? 162 TYR B CA 1 ATOM 4017 C C . TYR B 2 162 ? -13.247 74.186 8.665 1.00 22.00 ? 162 TYR B C 1 ATOM 4018 O O . TYR B 2 162 ? -12.211 73.804 9.221 1.00 23.11 ? 162 TYR B O 1 ATOM 4019 C CB . TYR B 2 162 ? -13.474 72.368 7.006 1.00 23.77 ? 162 TYR B CB 1 ATOM 4020 C CG . TYR B 2 162 ? -14.338 71.324 6.391 1.00 27.89 ? 162 TYR B CG 1 ATOM 4021 C CD1 . TYR B 2 162 ? -14.616 70.165 7.123 1.00 30.78 ? 162 TYR B CD1 1 ATOM 4022 C CD2 . TYR B 2 162 ? -14.909 71.496 5.138 1.00 25.31 ? 162 TYR B CD2 1 ATOM 4023 C CE1 . TYR B 2 162 ? -15.391 69.184 6.612 1.00 32.61 ? 162 TYR B CE1 1 ATOM 4024 C CE2 . TYR B 2 162 ? -15.726 70.447 4.591 1.00 33.36 ? 162 TYR B CE2 1 ATOM 4025 C CZ . TYR B 2 162 ? -15.956 69.318 5.377 1.00 37.63 ? 162 TYR B CZ 1 ATOM 4026 O OH . TYR B 2 162 ? -16.730 68.253 4.962 1.00 47.39 ? 162 TYR B OH 1 ATOM 4027 N N . SER B 2 163 ? -13.585 75.462 8.581 1.00 20.20 ? 163 SER B N 1 ATOM 4028 C CA . SER B 2 163 ? -12.540 76.454 8.960 1.00 23.30 ? 163 SER B CA 1 ATOM 4029 C C . SER B 2 163 ? -12.081 76.417 10.435 1.00 28.59 ? 163 SER B C 1 ATOM 4030 O O . SER B 2 163 ? -10.917 76.636 10.755 1.00 22.75 ? 163 SER B O 1 ATOM 4031 C CB . SER B 2 163 ? -12.982 77.866 8.594 1.00 28.29 ? 163 SER B CB 1 ATOM 4032 O OG . SER B 2 163 ? -14.123 78.261 9.285 1.00 36.63 ? 163 SER B OG 1 ATOM 4033 N N . GLU B 2 164 ? -12.992 76.143 11.351 1.00 24.53 ? 164 GLU B N 1 ATOM 4034 C CA . GLU B 2 164 ? -12.596 76.025 12.740 1.00 26.58 ? 164 GLU B CA 1 ATOM 4035 C C . GLU B 2 164 ? -11.771 74.793 13.044 1.00 24.84 ? 164 GLU B C 1 ATOM 4036 O O . GLU B 2 164 ? -10.764 74.876 13.715 1.00 23.91 ? 164 GLU B O 1 ATOM 4037 C CB . GLU B 2 164 ? -13.821 76.118 13.655 1.00 26.40 ? 164 GLU B CB 1 ATOM 4038 C CG . GLU B 2 164 ? -13.476 76.236 15.141 1.00 41.62 ? 164 GLU B CG 1 ATOM 4039 C CD . GLU B 2 164 ? -12.802 77.562 15.528 1.00 43.23 ? 164 GLU B CD 1 ATOM 4040 O OE1 . GLU B 2 164 ? -12.707 78.495 14.675 1.00 49.30 ? 164 GLU B OE1 1 ATOM 4041 O OE2 . GLU B 2 164 ? -12.355 77.643 16.696 1.00 58.93 ? 164 GLU B OE2 1 ATOM 4042 N N . GLU B 2 165 ? -12.142 73.647 12.464 1.00 22.11 ? 165 GLU B N 1 ATOM 4043 C CA . GLU B 2 165 ? -11.334 72.447 12.645 1.00 24.09 ? 165 GLU B CA 1 ATOM 4044 C C . GLU B 2 165 ? -9.931 72.681 12.095 1.00 24.54 ? 165 GLU B C 1 ATOM 4045 O O . GLU B 2 165 ? -8.920 72.307 12.702 1.00 21.73 ? 165 GLU B O 1 ATOM 4046 C CB . GLU B 2 165 ? -11.997 71.221 11.939 1.00 23.06 ? 165 GLU B CB 1 ATOM 4047 C CG . GLU B 2 165 ? -11.195 69.954 12.073 1.00 23.22 ? 165 GLU B CG 1 ATOM 4048 C CD . GLU B 2 165 ? -11.871 68.761 11.327 1.00 25.43 ? 165 GLU B CD 1 ATOM 4049 O OE1 . GLU B 2 165 ? -12.998 68.941 10.764 1.00 29.78 ? 165 GLU B OE1 1 ATOM 4050 O OE2 . GLU B 2 165 ? -11.238 67.702 11.250 1.00 25.82 ? 165 GLU B OE2 1 ATOM 4051 N N . ALA B 2 166 ? -9.879 73.321 10.919 1.00 22.98 ? 166 ALA B N 1 ATOM 4052 C CA . ALA B 2 166 ? -8.580 73.570 10.349 1.00 23.01 ? 166 ALA B CA 1 ATOM 4053 C C . ALA B 2 166 ? -7.775 74.562 11.223 1.00 18.66 ? 166 ALA B C 1 ATOM 4054 O O . ALA B 2 166 ? -6.583 74.357 11.396 1.00 23.02 ? 166 ALA B O 1 ATOM 4055 C CB . ALA B 2 166 ? -8.740 74.139 8.916 1.00 22.50 ? 166 ALA B CB 1 ATOM 4056 N N . ARG B 2 167 ? -8.431 75.607 11.706 1.00 23.43 ? 167 ARG B N 1 ATOM 4057 C CA . ARG B 2 167 ? -7.724 76.601 12.574 1.00 24.08 ? 167 ARG B CA 1 ATOM 4058 C C . ARG B 2 167 ? -7.123 75.937 13.781 1.00 24.55 ? 167 ARG B C 1 ATOM 4059 O O . ARG B 2 167 ? -5.960 76.136 14.133 1.00 25.46 ? 167 ARG B O 1 ATOM 4060 C CB . ARG B 2 167 ? -8.676 77.678 13.029 1.00 28.52 ? 167 ARG B CB 1 ATOM 4061 C CG . ARG B 2 167 ? -7.989 78.848 13.831 1.00 28.41 ? 167 ARG B CG 1 ATOM 4062 C CD . ARG B 2 167 ? -8.982 79.748 14.508 1.00 33.18 ? 167 ARG B CD 1 ATOM 4063 N NE . ARG B 2 167 ? -9.750 79.037 15.530 1.00 32.97 ? 167 ARG B NE 1 ATOM 4064 C CZ . ARG B 2 167 ? -9.295 78.688 16.733 1.00 36.80 ? 167 ARG B CZ 1 ATOM 4065 N NH1 . ARG B 2 167 ? -8.060 78.971 17.120 1.00 34.99 ? 167 ARG B NH1 1 ATOM 4066 N NH2 . ARG B 2 167 ? -10.102 78.025 17.563 1.00 40.04 ? 167 ARG B NH2 1 ATOM 4067 N N . LEU B 2 168 ? -7.905 75.050 14.423 1.00 23.76 ? 168 LEU B N 1 ATOM 4068 C CA . LEU B 2 168 ? -7.353 74.349 15.582 1.00 24.21 ? 168 LEU B CA 1 ATOM 4069 C C . LEU B 2 168 ? -6.147 73.540 15.221 1.00 26.03 ? 168 LEU B C 1 ATOM 4070 O O . LEU B 2 168 ? -5.161 73.499 15.968 1.00 27.18 ? 168 LEU B O 1 ATOM 4071 C CB . LEU B 2 168 ? -8.416 73.392 16.186 1.00 24.82 ? 168 LEU B CB 1 ATOM 4072 C CG . LEU B 2 168 ? -9.570 74.124 16.873 1.00 32.93 ? 168 LEU B CG 1 ATOM 4073 C CD1 . LEU B 2 168 ? -10.749 73.119 17.041 1.00 28.16 ? 168 LEU B CD1 1 ATOM 4074 C CD2 . LEU B 2 168 ? -9.137 74.743 18.259 1.00 30.21 ? 168 LEU B CD2 1 ATOM 4075 N N . LYS B 2 169 ? -6.192 72.872 14.071 1.00 24.34 ? 169 LYS B N 1 ATOM 4076 C CA . LYS B 2 169 ? -5.084 72.021 13.720 1.00 20.75 ? 169 LYS B CA 1 ATOM 4077 C C . LYS B 2 169 ? -3.857 72.914 13.319 1.00 23.69 ? 169 LYS B C 1 ATOM 4078 O O . LYS B 2 169 ? -2.702 72.615 13.688 1.00 27.72 ? 169 LYS B O 1 ATOM 4079 C CB . LYS B 2 169 ? -5.448 71.100 12.540 1.00 21.62 ? 169 LYS B CB 1 ATOM 4080 C CG . LYS B 2 169 ? -4.259 70.199 12.070 1.00 30.43 ? 169 LYS B CG 1 ATOM 4081 C CD . LYS B 2 169 ? -3.941 69.174 13.119 1.00 38.47 ? 169 LYS B CD 1 ATOM 4082 C CE . LYS B 2 169 ? -2.892 68.144 12.670 1.00 61.98 ? 169 LYS B CE 1 ATOM 4083 N NZ . LYS B 2 169 ? -3.309 67.210 11.556 1.00 73.32 ? 169 LYS B NZ 1 ATOM 4084 N N . ARG B 2 170 ? -4.140 73.987 12.579 1.00 25.32 ? 170 ARG B N 1 ATOM 4085 C CA . ARG B 2 170 ? -3.034 74.877 12.142 1.00 28.87 ? 170 ARG B CA 1 ATOM 4086 C C . ARG B 2 170 ? -2.331 75.420 13.372 1.00 32.52 ? 170 ARG B C 1 ATOM 4087 O O . ARG B 2 170 ? -1.114 75.567 13.376 1.00 36.24 ? 170 ARG B O 1 ATOM 4088 C CB . ARG B 2 170 ? -3.552 76.074 11.362 1.00 32.24 ? 170 ARG B CB 1 ATOM 4089 C CG . ARG B 2 170 ? -3.756 75.834 9.897 1.00 40.28 ? 170 ARG B CG 1 ATOM 4090 C CD . ARG B 2 170 ? -3.719 77.197 9.109 1.00 28.82 ? 170 ARG B CD 1 ATOM 4091 N NE . ARG B 2 170 ? -4.559 78.182 9.735 1.00 31.32 ? 170 ARG B NE 1 ATOM 4092 C CZ . ARG B 2 170 ? -5.868 78.285 9.587 1.00 26.80 ? 170 ARG B CZ 1 ATOM 4093 N NH1 . ARG B 2 170 ? -6.576 77.483 8.751 1.00 27.60 ? 170 ARG B NH1 1 ATOM 4094 N NH2 . ARG B 2 170 ? -6.508 79.248 10.266 1.00 32.71 ? 170 ARG B NH2 1 ATOM 4095 N N . GLU B 2 171 ? -3.111 75.747 14.405 1.00 29.80 ? 171 GLU B N 1 ATOM 4096 C CA . GLU B 2 171 ? -2.550 76.301 15.665 1.00 31.51 ? 171 GLU B CA 1 ATOM 4097 C C . GLU B 2 171 ? -1.765 75.281 16.453 1.00 37.08 ? 171 GLU B C 1 ATOM 4098 O O . GLU B 2 171 ? -0.731 75.630 17.052 1.00 31.13 ? 171 GLU B O 1 ATOM 4099 C CB . GLU B 2 171 ? -3.629 76.872 16.558 1.00 33.51 ? 171 GLU B CB 1 ATOM 4100 C CG . GLU B 2 171 ? -4.215 78.127 15.976 1.00 45.46 ? 171 GLU B CG 1 ATOM 4101 C CD . GLU B 2 171 ? -3.136 79.199 15.742 1.00 77.82 ? 171 GLU B CD 1 ATOM 4102 O OE1 . GLU B 2 171 ? -2.816 79.915 16.729 1.00 80.31 ? 171 GLU B OE1 1 ATOM 4103 O OE2 . GLU B 2 171 ? -2.601 79.306 14.594 1.00 72.32 ? 171 GLU B OE2 1 ATOM 4104 N N A GLU B 2 172 ? -2.257 74.043 16.484 0.50 28.78 ? 172 GLU B N 1 ATOM 4105 N N B GLU B 2 172 ? -2.253 74.038 16.497 0.50 28.78 ? 172 GLU B N 1 ATOM 4106 C CA A GLU B 2 172 ? -1.532 72.951 17.125 0.50 34.23 ? 172 GLU B CA 1 ATOM 4107 C CA B GLU B 2 172 ? -1.495 72.968 17.148 0.50 34.25 ? 172 GLU B CA 1 ATOM 4108 C C A GLU B 2 172 ? -0.163 72.810 16.505 0.50 32.85 ? 172 GLU B C 1 ATOM 4109 C C B GLU B 2 172 ? -0.138 72.889 16.508 0.50 32.83 ? 172 GLU B C 1 ATOM 4110 O O A GLU B 2 172 ? 0.845 72.669 17.205 0.50 34.09 ? 172 GLU B O 1 ATOM 4111 O O B GLU B 2 172 ? 0.886 72.883 17.199 0.50 33.85 ? 172 GLU B O 1 ATOM 4112 C CB A GLU B 2 172 ? -2.295 71.644 16.974 0.50 33.03 ? 172 GLU B CB 1 ATOM 4113 C CB B GLU B 2 172 ? -2.194 71.613 17.045 0.50 32.80 ? 172 GLU B CB 1 ATOM 4114 C CG A GLU B 2 172 ? -1.512 70.419 17.331 0.50 34.27 ? 172 GLU B CG 1 ATOM 4115 C CG B GLU B 2 172 ? -3.479 71.534 17.853 0.50 35.80 ? 172 GLU B CG 1 ATOM 4116 C CD A GLU B 2 172 ? -2.278 69.150 17.013 0.50 46.93 ? 172 GLU B CD 1 ATOM 4117 C CD B GLU B 2 172 ? -4.375 70.375 17.447 0.50 40.52 ? 172 GLU B CD 1 ATOM 4118 O OE1 A GLU B 2 172 ? -1.638 68.103 16.812 0.50 55.29 ? 172 GLU B OE1 1 ATOM 4119 O OE1 B GLU B 2 172 ? -3.873 69.414 16.825 0.50 46.41 ? 172 GLU B OE1 1 ATOM 4120 O OE2 A GLU B 2 172 ? -3.527 69.203 16.948 0.50 46.41 ? 172 GLU B OE2 1 ATOM 4121 O OE2 B GLU B 2 172 ? -5.591 70.437 17.735 0.50 31.69 ? 172 GLU B OE2 1 ATOM 4122 N N . ILE B 2 173 ? -0.130 72.859 15.183 1.00 34.00 ? 173 ILE B N 1 ATOM 4123 C CA . ILE B 2 173 ? 1.117 72.707 14.449 1.00 32.68 ? 173 ILE B CA 1 ATOM 4124 C C . ILE B 2 173 ? 2.021 73.916 14.681 1.00 32.76 ? 173 ILE B C 1 ATOM 4125 O O . ILE B 2 173 ? 3.224 73.762 14.968 1.00 38.90 ? 173 ILE B O 1 ATOM 4126 C CB . ILE B 2 173 ? 0.844 72.523 12.958 1.00 31.14 ? 173 ILE B CB 1 ATOM 4127 C CG1 . ILE B 2 173 ? 0.239 71.147 12.740 1.00 29.48 ? 173 ILE B CG1 1 ATOM 4128 C CG2 . ILE B 2 173 ? 2.160 72.619 12.165 1.00 40.30 ? 173 ILE B CG2 1 ATOM 4129 C CD1 . ILE B 2 173 ? -0.354 70.952 11.330 1.00 33.82 ? 173 ILE B CD1 1 ATOM 4130 N N . SER B 2 174 ? 1.445 75.112 14.577 1.00 29.24 ? 174 SER B N 1 ATOM 4131 C CA . SER B 2 174 ? 2.249 76.326 14.648 1.00 35.72 ? 174 SER B CA 1 ATOM 4132 C C . SER B 2 174 ? 2.814 76.554 16.067 1.00 44.83 ? 174 SER B C 1 ATOM 4133 O O . SER B 2 174 ? 3.922 77.092 16.214 1.00 42.24 ? 174 SER B O 1 ATOM 4134 C CB . SER B 2 174 ? 1.496 77.543 14.049 1.00 41.88 ? 174 SER B CB 1 ATOM 4135 O OG . SER B 2 174 ? 0.635 78.143 14.995 1.00 53.99 ? 174 SER B OG 1 ATOM 4136 N N . SER B 2 175 ? 2.057 76.122 17.083 1.00 39.08 ? 175 SER B N 1 ATOM 4137 C CA . SER B 2 175 ? 2.484 76.091 18.497 1.00 38.53 ? 175 SER B CA 1 ATOM 4138 C C . SER B 2 175 ? 3.554 75.057 18.826 1.00 46.36 ? 175 SER B C 1 ATOM 4139 O O . SER B 2 175 ? 4.201 75.150 19.867 1.00 46.12 ? 175 SER B O 1 ATOM 4140 C CB . SER B 2 175 ? 1.291 75.741 19.402 1.00 40.70 ? 175 SER B CB 1 ATOM 4141 O OG . SER B 2 175 ? 0.233 76.652 19.252 1.00 53.59 ? 175 SER B OG 1 ATOM 4142 N N . GLY B 2 176 ? 3.698 74.039 17.986 1.00 41.60 ? 176 GLY B N 1 ATOM 4143 C CA . GLY B 2 176 ? 4.764 73.068 18.146 1.00 40.70 ? 176 GLY B CA 1 ATOM 4144 C C . GLY B 2 176 ? 4.542 72.164 19.338 1.00 60.90 ? 176 GLY B C 1 ATOM 4145 O O . GLY B 2 176 ? 4.794 70.966 19.239 1.00 71.22 ? 176 GLY B O 1 ATOM 4146 N N . GLN C 3 1 ? -29.025 68.508 -35.343 1.00 64.35 ? 1 GLN H N 1 ATOM 4147 C CA . GLN C 3 1 ? -29.278 67.299 -34.567 1.00 52.95 ? 1 GLN H CA 1 ATOM 4148 C C . GLN C 3 1 ? -28.638 66.070 -35.219 1.00 32.81 ? 1 GLN H C 1 ATOM 4149 O O . GLN C 3 1 ? -29.011 65.609 -36.300 1.00 35.26 ? 1 GLN H O 1 ATOM 4150 C CB . GLN C 3 1 ? -30.776 67.095 -34.291 1.00 54.76 ? 1 GLN H CB 1 ATOM 4151 C CG . GLN C 3 1 ? -31.650 67.034 -35.534 1.00 67.96 ? 1 GLN H CG 1 ATOM 4152 C CD . GLN C 3 1 ? -31.684 68.346 -36.293 1.00 66.94 ? 1 GLN H CD 1 ATOM 4153 O OE1 . GLN C 3 1 ? -31.237 69.374 -35.788 1.00 73.71 ? 1 GLN H OE1 1 ATOM 4154 N NE2 . GLN C 3 1 ? -32.196 68.314 -37.518 1.00 67.34 ? 1 GLN H NE2 1 ATOM 4155 N N . VAL C 3 2 ? -27.640 65.554 -34.522 1.00 36.61 ? 2 VAL H N 1 ATOM 4156 C CA . VAL C 3 2 ? -26.900 64.400 -35.009 1.00 34.73 ? 2 VAL H CA 1 ATOM 4157 C C . VAL C 3 2 ? -27.781 63.156 -35.110 1.00 26.58 ? 2 VAL H C 1 ATOM 4158 O O . VAL C 3 2 ? -28.626 62.897 -34.235 1.00 29.66 ? 2 VAL H O 1 ATOM 4159 C CB . VAL C 3 2 ? -25.661 64.123 -34.103 1.00 30.61 ? 2 VAL H CB 1 ATOM 4160 C CG1 . VAL C 3 2 ? -25.054 62.799 -34.425 1.00 36.07 ? 2 VAL H CG1 1 ATOM 4161 C CG2 . VAL C 3 2 ? -24.604 65.181 -34.379 1.00 44.49 ? 2 VAL H CG2 1 ATOM 4162 N N . GLN C 3 3 ? -27.565 62.389 -36.176 1.00 22.87 ? 3 GLN H N 1 ATOM 4163 C CA . GLN C 3 3 ? -28.161 61.068 -36.263 1.00 21.01 ? 3 GLN H CA 1 ATOM 4164 C C . GLN C 3 3 ? -27.018 60.101 -36.488 1.00 24.61 ? 3 GLN H C 1 ATOM 4165 O O . GLN C 3 3 ? -26.009 60.441 -37.114 1.00 25.93 ? 3 GLN H O 1 ATOM 4166 C CB . GLN C 3 3 ? -29.097 60.983 -37.472 1.00 30.01 ? 3 GLN H CB 1 ATOM 4167 C CG . GLN C 3 3 ? -30.436 61.688 -37.239 1.00 48.36 ? 3 GLN H CG 1 ATOM 4168 C CD . GLN C 3 3 ? -31.404 61.364 -38.358 1.00 70.93 ? 3 GLN H CD 1 ATOM 4169 O OE1 . GLN C 3 3 ? -31.327 60.285 -38.978 1.00 56.22 ? 3 GLN H OE1 1 ATOM 4170 N NE2 . GLN C 3 3 ? -32.307 62.296 -38.639 1.00 86.50 ? 3 GLN H NE2 1 ATOM 4171 N N . LEU C 3 4 ? -27.156 58.903 -35.952 1.00 20.57 ? 4 LEU H N 1 ATOM 4172 C CA . LEU C 3 4 ? -26.119 57.873 -36.233 1.00 19.61 ? 4 LEU H CA 1 ATOM 4173 C C . LEU C 3 4 ? -26.771 56.905 -37.241 1.00 22.53 ? 4 LEU H C 1 ATOM 4174 O O . LEU C 3 4 ? -27.878 56.364 -36.977 1.00 21.90 ? 4 LEU H O 1 ATOM 4175 C CB . LEU C 3 4 ? -25.759 57.111 -34.924 1.00 17.31 ? 4 LEU H CB 1 ATOM 4176 C CG . LEU C 3 4 ? -25.201 58.002 -33.807 1.00 20.45 ? 4 LEU H CG 1 ATOM 4177 C CD1 . LEU C 3 4 ? -24.877 57.113 -32.577 1.00 19.65 ? 4 LEU H CD1 1 ATOM 4178 C CD2 . LEU C 3 4 ? -23.931 58.684 -34.291 1.00 22.26 ? 4 LEU H CD2 1 ATOM 4179 N N . VAL C 3 5 ? -26.095 56.667 -38.351 1.00 18.22 ? 5 VAL H N 1 ATOM 4180 C CA . VAL C 3 5 ? -26.627 55.826 -39.452 1.00 18.95 ? 5 VAL H CA 1 ATOM 4181 C C . VAL C 3 5 ? -25.670 54.662 -39.646 1.00 19.57 ? 5 VAL H C 1 ATOM 4182 O O . VAL C 3 5 ? -24.485 54.820 -40.003 1.00 20.52 ? 5 VAL H O 1 ATOM 4183 C CB . VAL C 3 5 ? -26.685 56.614 -40.786 1.00 24.47 ? 5 VAL H CB 1 ATOM 4184 C CG1 . VAL C 3 5 ? -27.202 55.664 -41.946 1.00 27.34 ? 5 VAL H CG1 1 ATOM 4185 C CG2 . VAL C 3 5 ? -27.598 57.809 -40.643 1.00 27.71 ? 5 VAL H CG2 1 ATOM 4186 N N . GLN C 3 6 ? -26.185 53.459 -39.424 1.00 17.36 ? 6 GLN H N 1 ATOM 4187 C CA . GLN C 3 6 ? -25.358 52.269 -39.512 1.00 17.08 ? 6 GLN H CA 1 ATOM 4188 C C . GLN C 3 6 ? -25.439 51.627 -40.888 1.00 18.31 ? 6 GLN H C 1 ATOM 4189 O O . GLN C 3 6 ? -26.403 51.843 -41.645 1.00 21.57 ? 6 GLN H O 1 ATOM 4190 C CB . GLN C 3 6 ? -25.811 51.213 -38.496 1.00 18.48 ? 6 GLN H CB 1 ATOM 4191 C CG . GLN C 3 6 ? -25.743 51.784 -37.031 1.00 20.29 ? 6 GLN H CG 1 ATOM 4192 C CD . GLN C 3 6 ? -26.118 50.767 -35.967 1.00 15.02 ? 6 GLN H CD 1 ATOM 4193 O OE1 . GLN C 3 6 ? -26.723 51.130 -34.930 1.00 19.26 ? 6 GLN H OE1 1 ATOM 4194 N NE2 . GLN C 3 6 ? -25.742 49.491 -36.178 1.00 18.26 ? 6 GLN H NE2 1 ATOM 4195 N N . SER C 3 7 ? -24.458 50.787 -41.172 1.00 18.93 ? 7 SER H N 1 ATOM 4196 C CA . SER C 3 7 ? -24.445 50.034 -42.412 1.00 18.96 ? 7 SER H CA 1 ATOM 4197 C C . SER C 3 7 ? -25.515 48.957 -42.369 1.00 23.13 ? 7 SER H C 1 ATOM 4198 O O . SER C 3 7 ? -26.135 48.694 -41.319 1.00 20.15 ? 7 SER H O 1 ATOM 4199 C CB . SER C 3 7 ? -23.031 49.452 -42.614 1.00 21.67 ? 7 SER H CB 1 ATOM 4200 O OG . SER C 3 7 ? -22.592 48.755 -41.443 1.00 20.16 ? 7 SER H OG 1 ATOM 4201 N N . GLY C 3 8 ? -25.733 48.358 -43.529 1.00 21.47 ? 8 GLY H N 1 ATOM 4202 C CA . GLY C 3 8 ? -26.848 47.456 -43.728 1.00 21.07 ? 8 GLY H CA 1 ATOM 4203 C C . GLY C 3 8 ? -26.710 46.023 -43.242 1.00 20.37 ? 8 GLY H C 1 ATOM 4204 O O . GLY C 3 8 ? -25.669 45.595 -42.784 1.00 23.55 ? 8 GLY H O 1 ATOM 4205 N N . ALA C 3 9 ? -27.799 45.268 -43.341 1.00 20.73 ? 9 ALA H N 1 ATOM 4206 C CA . ALA C 3 9 ? -27.786 43.894 -42.784 1.00 20.58 ? 9 ALA H CA 1 ATOM 4207 C C . ALA C 3 9 ? -26.704 43.017 -43.412 1.00 21.14 ? 9 ALA H C 1 ATOM 4208 O O . ALA C 3 9 ? -26.341 43.173 -44.587 1.00 24.58 ? 9 ALA H O 1 ATOM 4209 C CB . ALA C 3 9 ? -29.134 43.249 -43.003 1.00 23.84 ? 9 ALA H CB 1 ATOM 4210 N N . GLU C 3 10 ? -26.195 42.107 -42.616 1.00 20.75 ? 10 GLU H N 1 ATOM 4211 C CA . GLU C 3 10 ? -25.083 41.221 -43.035 1.00 20.05 ? 10 GLU H CA 1 ATOM 4212 C C . GLU C 3 10 ? -25.490 39.754 -42.862 1.00 23.62 ? 10 GLU H C 1 ATOM 4213 O O . GLU C 3 10 ? -26.145 39.402 -41.886 1.00 24.30 ? 10 GLU H O 1 ATOM 4214 C CB . GLU C 3 10 ? -23.898 41.469 -42.103 1.00 21.76 ? 10 GLU H CB 1 ATOM 4215 C CG . GLU C 3 10 ? -23.427 42.953 -42.176 1.00 23.52 ? 10 GLU H CG 1 ATOM 4216 C CD . GLU C 3 10 ? -22.335 43.209 -43.219 1.00 35.12 ? 10 GLU H CD 1 ATOM 4217 O OE1 . GLU C 3 10 ? -21.913 42.275 -43.929 1.00 32.00 ? 10 GLU H OE1 1 ATOM 4218 O OE2 . GLU C 3 10 ? -21.886 44.383 -43.317 1.00 31.99 ? 10 GLU H OE2 1 ATOM 4219 N N . VAL C 3 11 ? -25.101 38.914 -43.822 1.00 21.84 ? 11 VAL H N 1 ATOM 4220 C CA . VAL C 3 11 ? -25.297 37.451 -43.743 1.00 21.88 ? 11 VAL H CA 1 ATOM 4221 C C . VAL C 3 11 ? -23.911 36.815 -43.872 1.00 20.78 ? 11 VAL H C 1 ATOM 4222 O O . VAL C 3 11 ? -23.156 37.103 -44.844 1.00 24.77 ? 11 VAL H O 1 ATOM 4223 C CB . VAL C 3 11 ? -26.229 36.953 -44.880 1.00 27.91 ? 11 VAL H CB 1 ATOM 4224 C CG1 . VAL C 3 11 ? -26.359 35.451 -44.813 1.00 27.84 ? 11 VAL H CG1 1 ATOM 4225 C CG2 . VAL C 3 11 ? -27.609 37.640 -44.746 1.00 29.71 ? 11 VAL H CG2 1 ATOM 4226 N N . LYS C 3 12 ? -23.514 36.095 -42.837 1.00 19.45 ? 12 LYS H N 1 ATOM 4227 C CA . LYS C 3 12 ? -22.138 35.646 -42.695 1.00 21.87 ? 12 LYS H CA 1 ATOM 4228 C C . LYS C 3 12 ? -22.091 34.165 -42.424 1.00 22.28 ? 12 LYS H C 1 ATOM 4229 O O . LYS C 3 12 ? -22.986 33.613 -41.795 1.00 23.90 ? 12 LYS H O 1 ATOM 4230 C CB . LYS C 3 12 ? -21.486 36.377 -41.510 1.00 20.52 ? 12 LYS H CB 1 ATOM 4231 C CG . LYS C 3 12 ? -21.426 37.864 -41.799 1.00 21.62 ? 12 LYS H CG 1 ATOM 4232 C CD . LYS C 3 12 ? -20.260 38.034 -42.776 1.00 25.20 ? 12 LYS H CD 1 ATOM 4233 C CE . LYS C 3 12 ? -20.039 39.456 -43.230 1.00 36.53 ? 12 LYS H CE 1 ATOM 4234 N NZ . LYS C 3 12 ? -18.809 39.462 -44.104 1.00 39.65 ? 12 LYS H NZ 1 ATOM 4235 N N . LYS C 3 13 ? -21.018 33.524 -42.875 1.00 21.71 ? 13 LYS H N 1 ATOM 4236 C CA . LYS C 3 13 ? -20.828 32.113 -42.605 1.00 22.42 ? 13 LYS H CA 1 ATOM 4237 C C . LYS C 3 13 ? -19.938 31.912 -41.392 1.00 21.81 ? 13 LYS H C 1 ATOM 4238 O O . LYS C 3 13 ? -19.145 32.799 -41.076 1.00 25.89 ? 13 LYS H O 1 ATOM 4239 C CB . LYS C 3 13 ? -20.117 31.533 -43.820 1.00 21.11 ? 13 LYS H CB 1 ATOM 4240 C CG . LYS C 3 13 ? -21.096 31.351 -44.977 1.00 24.24 ? 13 LYS H CG 1 ATOM 4241 C CD . LYS C 3 13 ? -20.327 30.818 -46.192 1.00 25.80 ? 13 LYS H CD 1 ATOM 4242 C CE . LYS C 3 13 ? -21.207 30.938 -47.437 1.00 30.28 ? 13 LYS H CE 1 ATOM 4243 N NZ . LYS C 3 13 ? -22.454 30.155 -47.245 1.00 32.77 ? 13 LYS H NZ 1 ATOM 4244 N N . PRO C 3 14 ? -20.042 30.765 -40.714 1.00 22.06 ? 14 PRO H N 1 ATOM 4245 C CA . PRO C 3 14 ? -19.231 30.518 -39.513 1.00 23.54 ? 14 PRO H CA 1 ATOM 4246 C C . PRO C 3 14 ? -17.742 30.668 -39.720 1.00 26.99 ? 14 PRO H C 1 ATOM 4247 O O . PRO C 3 14 ? -17.146 30.148 -40.691 1.00 26.39 ? 14 PRO H O 1 ATOM 4248 C CB . PRO C 3 14 ? -19.545 29.058 -39.157 1.00 27.11 ? 14 PRO H CB 1 ATOM 4249 C CG . PRO C 3 14 ? -20.134 28.493 -40.349 1.00 31.61 ? 14 PRO H CG 1 ATOM 4250 C CD . PRO C 3 14 ? -20.864 29.590 -41.062 1.00 24.42 ? 14 PRO H CD 1 ATOM 4251 N N . GLY C 3 15 ? -17.106 31.339 -38.770 1.00 23.21 ? 15 GLY H N 1 ATOM 4252 C CA . GLY C 3 15 ? -15.674 31.567 -38.813 1.00 24.85 ? 15 GLY H CA 1 ATOM 4253 C C . GLY C 3 15 ? -15.298 32.855 -39.486 1.00 21.01 ? 15 GLY H C 1 ATOM 4254 O O . GLY C 3 15 ? -14.152 33.304 -39.413 1.00 25.78 ? 15 GLY H O 1 ATOM 4255 N N . SER C 3 16 ? -16.252 33.480 -40.164 1.00 20.38 ? 16 SER H N 1 ATOM 4256 C CA . SER C 3 16 ? -15.930 34.718 -40.885 1.00 22.98 ? 16 SER H CA 1 ATOM 4257 C C . SER C 3 16 ? -15.891 35.927 -39.926 1.00 22.37 ? 16 SER H C 1 ATOM 4258 O O . SER C 3 16 ? -16.084 35.757 -38.708 1.00 22.95 ? 16 SER H O 1 ATOM 4259 C CB . SER C 3 16 ? -16.967 35.022 -41.969 1.00 26.95 ? 16 SER H CB 1 ATOM 4260 O OG . SER C 3 16 ? -18.286 35.206 -41.433 1.00 22.40 ? 16 SER H OG 1 ATOM 4261 N N A SER C 3 17 ? -15.634 37.106 -40.485 0.56 21.70 ? 17 SER H N 1 ATOM 4262 N N B SER C 3 17 ? -15.641 37.103 -40.487 0.44 21.71 ? 17 SER H N 1 ATOM 4263 C CA A SER C 3 17 ? -15.653 38.367 -39.709 0.56 21.13 ? 17 SER H CA 1 ATOM 4264 C CA B SER C 3 17 ? -15.651 38.355 -39.717 0.44 21.18 ? 17 SER H CA 1 ATOM 4265 C C A SER C 3 17 ? -16.622 39.361 -40.332 0.56 23.84 ? 17 SER H C 1 ATOM 4266 C C B SER C 3 17 ? -16.710 39.286 -40.295 0.44 23.83 ? 17 SER H C 1 ATOM 4267 O O A SER C 3 17 ? -16.857 39.347 -41.559 0.56 23.52 ? 17 SER H O 1 ATOM 4268 O O B SER C 3 17 ? -17.123 39.126 -41.447 0.44 23.49 ? 17 SER H O 1 ATOM 4269 C CB A SER C 3 17 ? -14.269 39.009 -39.655 0.56 25.60 ? 17 SER H CB 1 ATOM 4270 C CB B SER C 3 17 ? -14.268 39.014 -39.747 0.44 25.59 ? 17 SER H CB 1 ATOM 4271 O OG A SER C 3 17 ? -13.901 39.466 -40.929 0.56 32.35 ? 17 SER H OG 1 ATOM 4272 O OG B SER C 3 17 ? -13.308 38.154 -39.146 0.44 27.40 ? 17 SER H OG 1 ATOM 4273 N N . VAL C 3 18 ? -17.167 40.255 -39.499 1.00 20.08 ? 18 VAL H N 1 ATOM 4274 C CA . VAL C 3 18 ? -18.126 41.258 -39.987 1.00 19.34 ? 18 VAL H CA 1 ATOM 4275 C C . VAL C 3 18 ? -17.639 42.597 -39.476 1.00 21.31 ? 18 VAL H C 1 ATOM 4276 O O . VAL C 3 18 ? -17.215 42.681 -38.321 1.00 21.10 ? 18 VAL H O 1 ATOM 4277 C CB . VAL C 3 18 ? -19.588 40.966 -39.508 1.00 22.46 ? 18 VAL H CB 1 ATOM 4278 C CG1 . VAL C 3 18 ? -19.738 40.915 -37.977 1.00 22.57 ? 18 VAL H CG1 1 ATOM 4279 C CG2 . VAL C 3 18 ? -20.561 41.964 -40.176 1.00 24.46 ? 18 VAL H CG2 1 ATOM 4280 N N . LYS C 3 19 ? -17.704 43.629 -40.305 1.00 21.97 ? 19 LYS H N 1 ATOM 4281 C CA . LYS C 3 19 ? -17.329 44.950 -39.806 1.00 19.21 ? 19 LYS H CA 1 ATOM 4282 C C . LYS C 3 19 ? -18.491 45.905 -40.071 1.00 21.20 ? 19 LYS H C 1 ATOM 4283 O O . LYS C 3 19 ? -18.870 46.108 -41.213 1.00 24.21 ? 19 LYS H O 1 ATOM 4284 C CB . LYS C 3 19 ? -16.078 45.444 -40.538 1.00 23.31 ? 19 LYS H CB 1 ATOM 4285 C CG . LYS C 3 19 ? -15.571 46.811 -40.021 1.00 22.04 ? 19 LYS H CG 1 ATOM 4286 C CD . LYS C 3 19 ? -14.120 47.074 -40.540 1.00 25.29 ? 19 LYS H CD 1 ATOM 4287 C CE . LYS C 3 19 ? -13.552 48.426 -40.047 1.00 31.68 ? 19 LYS H CE 1 ATOM 4288 N NZ . LYS C 3 19 ? -12.146 48.588 -40.560 1.00 28.35 ? 19 LYS H NZ 1 ATOM 4289 N N . VAL C 3 20 ? -19.065 46.469 -39.021 1.00 17.60 ? 20 VAL H N 1 ATOM 4290 C CA . VAL C 3 20 ? -20.274 47.294 -39.144 1.00 20.30 ? 20 VAL H CA 1 ATOM 4291 C C . VAL C 3 20 ? -19.803 48.757 -38.931 1.00 20.26 ? 20 VAL H C 1 ATOM 4292 O O . VAL C 3 20 ? -18.918 49.011 -38.108 1.00 20.09 ? 20 VAL H O 1 ATOM 4293 C CB . VAL C 3 20 ? -21.246 46.937 -37.961 1.00 20.65 ? 20 VAL H CB 1 ATOM 4294 C CG1 . VAL C 3 20 ? -22.492 47.785 -38.052 1.00 18.85 ? 20 VAL H CG1 1 ATOM 4295 C CG2 . VAL C 3 20 ? -21.655 45.453 -38.090 1.00 25.97 ? 20 VAL H CG2 1 ATOM 4296 N N . SER C 3 21 ? -20.390 49.687 -39.675 1.00 18.07 ? 21 SER H N 1 ATOM 4297 C CA . SER C 3 21 ? -20.023 51.109 -39.525 1.00 19.08 ? 21 SER H CA 1 ATOM 4298 C C . SER C 3 21 ? -21.172 51.914 -38.931 1.00 20.98 ? 21 SER H C 1 ATOM 4299 O O . SER C 3 21 ? -22.360 51.525 -38.995 1.00 20.11 ? 21 SER H O 1 ATOM 4300 C CB . SER C 3 21 ? -19.598 51.689 -40.894 1.00 20.49 ? 21 SER H CB 1 ATOM 4301 O OG . SER C 3 21 ? -20.700 51.654 -41.796 1.00 23.33 ? 21 SER H OG 1 ATOM 4302 N N . CYS C 3 22 ? -20.805 53.047 -38.344 1.00 17.42 ? 22 CYS H N 1 ATOM 4303 C CA . CYS C 3 22 ? -21.761 53.957 -37.660 1.00 19.17 ? 22 CYS H CA 1 ATOM 4304 C C . CYS C 3 22 ? -21.327 55.369 -38.036 1.00 21.58 ? 22 CYS H C 1 ATOM 4305 O O . CYS C 3 22 ? -20.318 55.851 -37.543 1.00 23.02 ? 22 CYS H O 1 ATOM 4306 C CB . CYS C 3 22 ? -21.614 53.711 -36.167 1.00 20.33 ? 22 CYS H CB 1 ATOM 4307 S SG . CYS C 3 22 ? -22.517 54.846 -35.088 1.00 26.59 ? 22 CYS H SG 1 ATOM 4308 N N . LYS C 3 23 ? -22.085 55.999 -38.943 1.00 18.65 ? 23 LYS H N 1 ATOM 4309 C CA . LYS C 3 23 ? -21.702 57.362 -39.392 1.00 19.64 ? 23 LYS H CA 1 ATOM 4310 C C . LYS C 3 23 ? -22.488 58.431 -38.655 1.00 21.13 ? 23 LYS H C 1 ATOM 4311 O O . LYS C 3 23 ? -23.721 58.340 -38.546 1.00 23.38 ? 23 LYS H O 1 ATOM 4312 C CB . LYS C 3 23 ? -22.005 57.467 -40.866 1.00 24.87 ? 23 LYS H CB 1 ATOM 4313 C CG . LYS C 3 23 ? -21.984 58.917 -41.374 1.00 30.88 ? 23 LYS H CG 1 ATOM 4314 C CD . LYS C 3 23 ? -20.602 59.243 -41.835 1.00 37.08 ? 23 LYS H CD 1 ATOM 4315 C CE . LYS C 3 23 ? -20.653 60.487 -42.797 1.00 39.48 ? 23 LYS H CE 1 ATOM 4316 N NZ . LYS C 3 23 ? -19.355 60.543 -43.510 1.00 43.50 ? 23 LYS H NZ 1 ATOM 4317 N N A SER C 3 24 ? -21.790 59.436 -38.146 0.62 20.62 ? 24 SER H N 1 ATOM 4318 N N B SER C 3 24 ? -21.781 59.418 -38.113 0.38 20.69 ? 24 SER H N 1 ATOM 4319 C CA A SER C 3 24 ? -22.453 60.523 -37.421 0.62 20.57 ? 24 SER H CA 1 ATOM 4320 C CA B SER C 3 24 ? -22.444 60.543 -37.457 0.38 20.68 ? 24 SER H CA 1 ATOM 4321 C C A SER C 3 24 ? -22.748 61.590 -38.466 0.62 24.79 ? 24 SER H C 1 ATOM 4322 C C B SER C 3 24 ? -22.753 61.532 -38.549 0.38 24.83 ? 24 SER H C 1 ATOM 4323 O O A SER C 3 24 ? -21.828 62.090 -39.118 0.62 24.71 ? 24 SER H O 1 ATOM 4324 O O B SER C 3 24 ? -21.853 61.965 -39.283 0.38 24.63 ? 24 SER H O 1 ATOM 4325 C CB A SER C 3 24 ? -21.557 61.052 -36.298 0.62 22.77 ? 24 SER H CB 1 ATOM 4326 C CB B SER C 3 24 ? -21.555 61.198 -36.404 0.38 22.80 ? 24 SER H CB 1 ATOM 4327 O OG A SER C 3 24 ? -22.169 62.129 -35.638 0.62 19.04 ? 24 SER H OG 1 ATOM 4328 O OG B SER C 3 24 ? -21.328 60.317 -35.333 0.38 22.93 ? 24 SER H OG 1 ATOM 4329 N N . SER C 3 25 ? -24.031 61.833 -38.697 1.00 25.02 ? 25 SER H N 1 ATOM 4330 C CA . SER C 3 25 ? -24.429 62.798 -39.720 1.00 33.49 ? 25 SER H CA 1 ATOM 4331 C C . SER C 3 25 ? -25.128 63.950 -39.076 1.00 29.34 ? 25 SER H C 1 ATOM 4332 O O . SER C 3 25 ? -25.690 63.837 -37.982 1.00 30.31 ? 25 SER H O 1 ATOM 4333 C CB . SER C 3 25 ? -25.227 62.170 -40.859 1.00 38.56 ? 25 SER H CB 1 ATOM 4334 O OG . SER C 3 25 ? -26.575 62.170 -40.522 1.00 42.66 ? 25 SER H OG 1 ATOM 4335 N N . GLY C 3 26 ? -25.001 65.123 -39.690 1.00 30.25 ? 26 GLY H N 1 ATOM 4336 C CA . GLY C 3 26 ? -25.611 66.262 -39.071 1.00 33.86 ? 26 GLY H CA 1 ATOM 4337 C C . GLY C 3 26 ? -24.722 66.861 -38.020 1.00 34.66 ? 26 GLY H C 1 ATOM 4338 O O . GLY C 3 26 ? -25.201 67.630 -37.176 1.00 39.65 ? 26 GLY H O 1 ATOM 4339 N N . GLY C 3 27 ? -23.451 66.440 -37.997 1.00 32.44 ? 27 GLY H N 1 ATOM 4340 C CA . GLY C 3 27 ? -22.552 66.943 -36.962 1.00 31.93 ? 27 GLY H CA 1 ATOM 4341 C C . GLY C 3 27 ? -21.608 65.823 -36.530 1.00 32.23 ? 27 GLY H C 1 ATOM 4342 O O . GLY C 3 27 ? -21.893 64.661 -36.845 1.00 29.00 ? 27 GLY H O 1 ATOM 4343 N N . THR C 3 28 ? -20.486 66.169 -35.892 1.00 26.49 ? 28 THR H N 1 ATOM 4344 C CA . THR C 3 28 ? -19.507 65.152 -35.500 1.00 26.97 ? 28 THR H CA 1 ATOM 4345 C C . THR C 3 28 ? -19.864 64.579 -34.158 1.00 23.82 ? 28 THR H C 1 ATOM 4346 O O . THR C 3 28 ? -20.592 65.214 -33.343 1.00 23.22 ? 28 THR H O 1 ATOM 4347 C CB . THR C 3 28 ? -18.060 65.750 -35.377 1.00 27.13 ? 28 THR H CB 1 ATOM 4348 O OG1 . THR C 3 28 ? -17.116 64.669 -35.214 1.00 22.73 ? 28 THR H OG1 1 ATOM 4349 C CG2 . THR C 3 28 ? -17.968 66.724 -34.165 1.00 28.31 ? 28 THR H CG2 1 ATOM 4350 N N . SER C 3 29 ? -19.342 63.374 -33.932 1.00 20.90 ? 29 SER H N 1 ATOM 4351 C CA . SER C 3 29 ? -19.418 62.743 -32.632 1.00 19.51 ? 29 SER H CA 1 ATOM 4352 C C . SER C 3 29 ? -18.016 62.468 -32.090 1.00 16.96 ? 29 SER H C 1 ATOM 4353 O O . SER C 3 29 ? -17.856 61.752 -31.107 1.00 19.34 ? 29 SER H O 1 ATOM 4354 C CB . SER C 3 29 ? -20.212 61.441 -32.724 1.00 22.27 ? 29 SER H CB 1 ATOM 4355 O OG . SER C 3 29 ? -21.556 61.782 -32.959 1.00 23.49 ? 29 SER H OG 1 ATOM 4356 N N . ASN C 3 30 ? -17.010 63.115 -32.673 1.00 18.18 ? 30 ASN H N 1 ATOM 4357 C CA . ASN C 3 30 ? -15.635 62.761 -32.316 1.00 19.71 ? 30 ASN H CA 1 ATOM 4358 C C . ASN C 3 30 ? -15.227 63.136 -30.908 1.00 18.26 ? 30 ASN H C 1 ATOM 4359 O O . ASN C 3 30 ? -14.286 62.543 -30.371 1.00 19.25 ? 30 ASN H O 1 ATOM 4360 C CB . ASN C 3 30 ? -14.602 63.436 -33.280 1.00 19.61 ? 30 ASN H CB 1 ATOM 4361 C CG . ASN C 3 30 ? -14.683 62.882 -34.677 1.00 23.97 ? 30 ASN H CG 1 ATOM 4362 O OD1 . ASN C 3 30 ? -15.173 61.783 -34.889 1.00 19.90 ? 30 ASN H OD1 1 ATOM 4363 N ND2 . ASN C 3 30 ? -14.250 63.653 -35.633 1.00 22.59 ? 30 ASN H ND2 1 ATOM 4364 N N . ASN C 3 31 ? -15.954 64.092 -30.323 1.00 19.08 ? 31 ASN H N 1 ATOM 4365 C CA . ASN C 3 31 ? -15.694 64.558 -28.971 1.00 17.80 ? 31 ASN H CA 1 ATOM 4366 C C . ASN C 3 31 ? -16.494 63.782 -27.921 1.00 18.17 ? 31 ASN H C 1 ATOM 4367 O O . ASN C 3 31 ? -16.480 64.112 -26.720 1.00 20.45 ? 31 ASN H O 1 ATOM 4368 C CB . ASN C 3 31 ? -15.998 66.072 -28.885 1.00 17.93 ? 31 ASN H CB 1 ATOM 4369 C CG . ASN C 3 31 ? -17.422 66.433 -29.291 1.00 19.74 ? 31 ASN H CG 1 ATOM 4370 O OD1 . ASN C 3 31 ? -17.922 66.000 -30.337 1.00 22.27 ? 31 ASN H OD1 1 ATOM 4371 N ND2 . ASN C 3 31 ? -18.029 67.324 -28.529 1.00 22.33 ? 31 ASN H ND2 1 ATOM 4372 N N . TYR C 3 32 ? -17.174 62.695 -28.354 1.00 16.56 ? 32 TYR H N 1 ATOM 4373 C CA . TYR C 3 32 ? -17.966 61.853 -27.440 1.00 16.51 ? 32 TYR H CA 1 ATOM 4374 C C . TYR C 3 32 ? -17.463 60.399 -27.544 1.00 18.00 ? 32 TYR H C 1 ATOM 4375 O O . TYR C 3 32 ? -16.790 60.023 -28.536 1.00 18.74 ? 32 TYR H O 1 ATOM 4376 C CB . TYR C 3 32 ? -19.436 61.770 -27.870 1.00 17.27 ? 32 TYR H CB 1 ATOM 4377 C CG . TYR C 3 32 ? -20.203 63.096 -27.789 1.00 16.62 ? 32 TYR H CG 1 ATOM 4378 C CD1 . TYR C 3 32 ? -20.136 64.014 -28.843 1.00 17.20 ? 32 TYR H CD1 1 ATOM 4379 C CD2 . TYR C 3 32 ? -20.965 63.399 -26.660 1.00 21.92 ? 32 TYR H CD2 1 ATOM 4380 C CE1 . TYR C 3 32 ? -20.868 65.216 -28.795 1.00 23.47 ? 32 TYR H CE1 1 ATOM 4381 C CE2 . TYR C 3 32 ? -21.736 64.602 -26.604 1.00 25.15 ? 32 TYR H CE2 1 ATOM 4382 C CZ . TYR C 3 32 ? -21.655 65.494 -27.680 1.00 27.83 ? 32 TYR H CZ 1 ATOM 4383 O OH . TYR C 3 32 ? -22.365 66.675 -27.599 1.00 32.36 ? 32 TYR H OH 1 ATOM 4384 N N . ALA C 3 33 ? -17.768 59.606 -26.517 1.00 18.25 ? 33 ALA H N 1 ATOM 4385 C CA . ALA C 3 33 ? -17.636 58.130 -26.616 1.00 17.50 ? 33 ALA H CA 1 ATOM 4386 C C . ALA C 3 33 ? -18.838 57.586 -27.397 1.00 19.39 ? 33 ALA H C 1 ATOM 4387 O O . ALA C 3 33 ? -19.972 58.045 -27.189 1.00 17.17 ? 33 ALA H O 1 ATOM 4388 C CB . ALA C 3 33 ? -17.616 57.454 -25.203 1.00 15.50 ? 33 ALA H CB 1 ATOM 4389 N N . ILE C 3 34 ? -18.546 56.610 -28.287 1.00 16.08 ? 34 ILE H N 1 ATOM 4390 C CA . ILE C 3 34 ? -19.615 55.812 -28.914 1.00 16.03 ? 34 ILE H CA 1 ATOM 4391 C C . ILE C 3 34 ? -19.371 54.347 -28.489 1.00 16.61 ? 34 ILE H C 1 ATOM 4392 O O . ILE C 3 34 ? -18.245 53.839 -28.598 1.00 18.46 ? 34 ILE H O 1 ATOM 4393 C CB . ILE C 3 34 ? -19.548 55.947 -30.409 1.00 18.90 ? 34 ILE H CB 1 ATOM 4394 C CG1 . ILE C 3 34 ? -20.191 57.301 -30.823 1.00 23.86 ? 34 ILE H CG1 1 ATOM 4395 C CG2 . ILE C 3 34 ? -20.329 54.795 -31.113 1.00 21.74 ? 34 ILE H CG2 1 ATOM 4396 C CD1 . ILE C 3 34 ? -20.334 57.545 -32.258 1.00 25.04 ? 34 ILE H CD1 1 ATOM 4397 N N . SER C 3 35 ? -20.426 53.699 -28.025 1.00 18.36 ? 35 SER H N 1 ATOM 4398 C CA . SER C 3 35 ? -20.340 52.296 -27.679 1.00 16.37 ? 35 SER H CA 1 ATOM 4399 C C . SER C 3 35 ? -21.025 51.439 -28.731 1.00 15.55 ? 35 SER H C 1 ATOM 4400 O O . SER C 3 35 ? -21.878 51.902 -29.482 1.00 17.50 ? 35 SER H O 1 ATOM 4401 C CB . SER C 3 35 ? -21.005 52.023 -26.339 1.00 19.52 ? 35 SER H CB 1 ATOM 4402 O OG . SER C 3 35 ? -20.086 52.382 -25.276 1.00 18.48 ? 35 SER H OG 1 ATOM 4403 N N . TRP C 3 36 ? -20.655 50.165 -28.734 1.00 16.03 ? 36 TRP H N 1 ATOM 4404 C CA . TRP C 3 36 ? -21.389 49.179 -29.523 1.00 17.24 ? 36 TRP H CA 1 ATOM 4405 C C . TRP C 3 36 ? -22.065 48.209 -28.548 1.00 16.07 ? 36 TRP H C 1 ATOM 4406 O O . TRP C 3 36 ? -21.465 47.721 -27.591 1.00 17.40 ? 36 TRP H O 1 ATOM 4407 C CB . TRP C 3 36 ? -20.389 48.385 -30.386 1.00 17.52 ? 36 TRP H CB 1 ATOM 4408 C CG . TRP C 3 36 ? -19.877 49.190 -31.516 1.00 16.76 ? 36 TRP H CG 1 ATOM 4409 C CD1 . TRP C 3 36 ? -18.705 49.872 -31.558 1.00 17.80 ? 36 TRP H CD1 1 ATOM 4410 C CD2 . TRP C 3 36 ? -20.539 49.409 -32.759 1.00 17.28 ? 36 TRP H CD2 1 ATOM 4411 N NE1 . TRP C 3 36 ? -18.593 50.508 -32.768 1.00 18.65 ? 36 TRP H NE1 1 ATOM 4412 C CE2 . TRP C 3 36 ? -19.693 50.240 -33.528 1.00 18.39 ? 36 TRP H CE2 1 ATOM 4413 C CE3 . TRP C 3 36 ? -21.739 48.918 -33.319 1.00 16.24 ? 36 TRP H CE3 1 ATOM 4414 C CZ2 . TRP C 3 36 ? -19.997 50.618 -34.847 1.00 18.43 ? 36 TRP H CZ2 1 ATOM 4415 C CZ3 . TRP C 3 36 ? -22.113 49.321 -34.614 1.00 18.87 ? 36 TRP H CZ3 1 ATOM 4416 C CH2 . TRP C 3 36 ? -21.203 50.159 -35.388 1.00 18.85 ? 36 TRP H CH2 1 ATOM 4417 N N . VAL C 3 37 ? -23.346 47.973 -28.787 1.00 14.39 ? 37 VAL H N 1 ATOM 4418 C CA . VAL C 3 37 ? -24.171 47.186 -27.840 1.00 15.71 ? 37 VAL H CA 1 ATOM 4419 C C . VAL C 3 37 ? -24.952 46.194 -28.717 1.00 17.70 ? 37 VAL H C 1 ATOM 4420 O O . VAL C 3 37 ? -25.523 46.664 -29.724 1.00 18.32 ? 37 VAL H O 1 ATOM 4421 C CB . VAL C 3 37 ? -25.219 48.093 -27.171 1.00 17.50 ? 37 VAL H CB 1 ATOM 4422 C CG1 . VAL C 3 37 ? -26.251 47.245 -26.408 1.00 17.33 ? 37 VAL H CG1 1 ATOM 4423 C CG2 . VAL C 3 37 ? -24.492 49.127 -26.246 1.00 16.19 ? 37 VAL H CG2 1 ATOM 4424 N N . ARG C 3 38 ? -24.938 44.885 -28.391 1.00 17.37 ? 38 ARG H N 1 ATOM 4425 C CA . ARG C 3 38 ? -25.673 44.001 -29.246 1.00 16.85 ? 38 ARG H CA 1 ATOM 4426 C C . ARG C 3 38 ? -26.857 43.396 -28.531 1.00 17.09 ? 38 ARG H C 1 ATOM 4427 O O . ARG C 3 38 ? -26.959 43.456 -27.292 1.00 18.59 ? 38 ARG H O 1 ATOM 4428 C CB . ARG C 3 38 ? -24.741 42.902 -29.777 1.00 20.60 ? 38 ARG H CB 1 ATOM 4429 C CG . ARG C 3 38 ? -24.475 41.802 -28.783 1.00 20.94 ? 38 ARG H CG 1 ATOM 4430 C CD . ARG C 3 38 ? -23.779 40.631 -29.620 1.00 19.23 ? 38 ARG H CD 1 ATOM 4431 N NE . ARG C 3 38 ? -23.509 39.482 -28.759 1.00 23.28 ? 38 ARG H NE 1 ATOM 4432 C CZ . ARG C 3 38 ? -22.712 38.466 -29.119 1.00 21.95 ? 38 ARG H CZ 1 ATOM 4433 N NH1 . ARG C 3 38 ? -22.086 38.519 -30.325 1.00 17.93 ? 38 ARG H NH1 1 ATOM 4434 N NH2 . ARG C 3 38 ? -22.564 37.419 -28.253 1.00 23.30 ? 38 ARG H NH2 1 ATOM 4435 N N . GLN C 3 39 ? -27.770 42.835 -29.302 1.00 17.83 ? 39 GLN H N 1 ATOM 4436 C CA . GLN C 3 39 ? -28.969 42.239 -28.674 1.00 16.24 ? 39 GLN H CA 1 ATOM 4437 C C . GLN C 3 39 ? -29.293 40.944 -29.474 1.00 21.55 ? 39 GLN H C 1 ATOM 4438 O O . GLN C 3 39 ? -29.797 41.012 -30.615 1.00 18.92 ? 39 GLN H O 1 ATOM 4439 C CB . GLN C 3 39 ? -30.093 43.252 -28.773 1.00 18.47 ? 39 GLN H CB 1 ATOM 4440 C CG . GLN C 3 39 ? -31.450 42.795 -28.169 1.00 21.04 ? 39 GLN H CG 1 ATOM 4441 C CD . GLN C 3 39 ? -32.391 43.990 -28.042 1.00 21.25 ? 39 GLN H CD 1 ATOM 4442 O OE1 . GLN C 3 39 ? -32.510 44.783 -28.982 1.00 24.61 ? 39 GLN H OE1 1 ATOM 4443 N NE2 . GLN C 3 39 ? -33.025 44.145 -26.847 1.00 22.98 ? 39 GLN H NE2 1 ATOM 4444 N N . ALA C 3 40 ? -28.984 39.821 -28.839 1.00 19.31 ? 40 ALA H N 1 ATOM 4445 C CA . ALA C 3 40 ? -29.276 38.507 -29.484 1.00 20.72 ? 40 ALA H CA 1 ATOM 4446 C C . ALA C 3 40 ? -30.792 38.289 -29.467 1.00 30.73 ? 40 ALA H C 1 ATOM 4447 O O . ALA C 3 40 ? -31.518 38.942 -28.731 1.00 29.27 ? 40 ALA H O 1 ATOM 4448 C CB . ALA C 3 40 ? -28.552 37.435 -28.775 1.00 24.81 ? 40 ALA H CB 1 ATOM 4449 N N . PRO C 3 41 ? -31.299 37.418 -30.355 1.00 30.82 ? 41 PRO H N 1 ATOM 4450 C CA . PRO C 3 41 ? -32.751 37.335 -30.524 1.00 33.20 ? 41 PRO H CA 1 ATOM 4451 C C . PRO C 3 41 ? -33.399 36.960 -29.235 1.00 34.40 ? 41 PRO H C 1 ATOM 4452 O O . PRO C 3 41 ? -32.995 36.012 -28.556 1.00 33.70 ? 41 PRO H O 1 ATOM 4453 C CB . PRO C 3 41 ? -32.904 36.179 -31.537 1.00 34.89 ? 41 PRO H CB 1 ATOM 4454 C CG . PRO C 3 41 ? -31.722 36.383 -32.434 1.00 33.73 ? 41 PRO H CG 1 ATOM 4455 C CD . PRO C 3 41 ? -30.587 36.797 -31.494 1.00 28.17 ? 41 PRO H CD 1 ATOM 4456 N N . GLY C 3 42 ? -34.367 37.773 -28.858 1.00 34.80 ? 42 GLY H N 1 ATOM 4457 C CA . GLY C 3 42 ? -35.101 37.497 -27.627 1.00 35.06 ? 42 GLY H CA 1 ATOM 4458 C C . GLY C 3 42 ? -34.314 37.808 -26.369 1.00 47.65 ? 42 GLY H C 1 ATOM 4459 O O . GLY C 3 42 ? -34.812 37.565 -25.269 1.00 39.06 ? 42 GLY H O 1 ATOM 4460 N N . GLN C 3 43 ? -33.093 38.340 -26.503 1.00 31.12 ? 43 GLN H N 1 ATOM 4461 C CA . GLN C 3 43 ? -32.291 38.561 -25.297 1.00 27.03 ? 43 GLN H CA 1 ATOM 4462 C C . GLN C 3 43 ? -32.108 40.072 -25.011 1.00 23.98 ? 43 GLN H C 1 ATOM 4463 O O . GLN C 3 43 ? -32.730 40.949 -25.670 1.00 25.01 ? 43 GLN H O 1 ATOM 4464 C CB . GLN C 3 43 ? -30.921 37.909 -25.389 1.00 27.73 ? 43 GLN H CB 1 ATOM 4465 C CG . GLN C 3 43 ? -30.975 36.456 -25.796 1.00 38.98 ? 43 GLN H CG 1 ATOM 4466 C CD . GLN C 3 43 ? -31.596 35.617 -24.727 1.00 51.67 ? 43 GLN H CD 1 ATOM 4467 O OE1 . GLN C 3 43 ? -31.211 35.702 -23.563 1.00 70.81 ? 43 GLN H OE1 1 ATOM 4468 N NE2 . GLN C 3 43 ? -32.580 34.808 -25.106 1.00 80.18 ? 43 GLN H NE2 1 ATOM 4469 N N . GLY C 3 44 ? -31.295 40.317 -23.999 1.00 24.22 ? 44 GLY H N 1 ATOM 4470 C CA . GLY C 3 44 ? -31.158 41.681 -23.520 1.00 26.14 ? 44 GLY H CA 1 ATOM 4471 C C . GLY C 3 44 ? -29.993 42.371 -24.201 1.00 25.43 ? 44 GLY H C 1 ATOM 4472 O O . GLY C 3 44 ? -29.268 41.765 -24.990 1.00 24.69 ? 44 GLY H O 1 ATOM 4473 N N . LEU C 3 45 ? -29.821 43.644 -23.872 1.00 20.55 ? 45 LEU H N 1 ATOM 4474 C CA . LEU C 3 45 ? -28.664 44.417 -24.348 1.00 17.76 ? 45 LEU H CA 1 ATOM 4475 C C . LEU C 3 45 ? -27.356 43.967 -23.713 1.00 18.70 ? 45 LEU H C 1 ATOM 4476 O O . LEU C 3 45 ? -27.277 43.605 -22.502 1.00 19.99 ? 45 LEU H O 1 ATOM 4477 C CB . LEU C 3 45 ? -28.903 45.883 -24.006 1.00 19.59 ? 45 LEU H CB 1 ATOM 4478 C CG . LEU C 3 45 ? -30.209 46.498 -24.506 1.00 21.34 ? 45 LEU H CG 1 ATOM 4479 C CD1 . LEU C 3 45 ? -30.416 47.932 -23.983 1.00 20.26 ? 45 LEU H CD1 1 ATOM 4480 C CD2 . LEU C 3 45 ? -30.282 46.484 -26.082 1.00 22.31 ? 45 LEU H CD2 1 ATOM 4481 N N . ASP C 3 46 ? -26.268 44.019 -24.497 1.00 18.99 ? 46 ASP H N 1 ATOM 4482 C CA . ASP C 3 46 ? -24.988 43.501 -24.025 1.00 18.37 ? 46 ASP H CA 1 ATOM 4483 C C . ASP C 3 46 ? -23.892 44.426 -24.604 1.00 19.31 ? 46 ASP H C 1 ATOM 4484 O O . ASP C 3 46 ? -23.784 44.572 -25.810 1.00 18.75 ? 46 ASP H O 1 ATOM 4485 C CB . ASP C 3 46 ? -24.849 42.093 -24.601 1.00 23.08 ? 46 ASP H CB 1 ATOM 4486 C CG . ASP C 3 46 ? -23.780 41.292 -23.933 1.00 23.72 ? 46 ASP H CG 1 ATOM 4487 O OD1 . ASP C 3 46 ? -23.262 41.706 -22.890 1.00 27.23 ? 46 ASP H OD1 1 ATOM 4488 O OD2 . ASP C 3 46 ? -23.494 40.176 -24.429 1.00 28.95 ? 46 ASP H OD2 1 ATOM 4489 N N . TRP C 3 47 ? -23.092 45.013 -23.738 1.00 19.33 ? 47 TRP H N 1 ATOM 4490 C CA . TRP C 3 47 ? -22.041 45.940 -24.189 1.00 18.27 ? 47 TRP H CA 1 ATOM 4491 C C . TRP C 3 47 ? -20.872 45.217 -24.780 1.00 18.77 ? 47 TRP H C 1 ATOM 4492 O O . TRP C 3 47 ? -20.362 44.266 -24.216 1.00 24.04 ? 47 TRP H O 1 ATOM 4493 C CB . TRP C 3 47 ? -21.543 46.739 -23.000 1.00 19.48 ? 47 TRP H CB 1 ATOM 4494 C CG . TRP C 3 47 ? -20.649 47.910 -23.292 1.00 18.57 ? 47 TRP H CG 1 ATOM 4495 C CD1 . TRP C 3 47 ? -21.035 49.084 -23.937 1.00 18.16 ? 47 TRP H CD1 1 ATOM 4496 C CD2 . TRP C 3 47 ? -19.300 48.120 -22.838 1.00 20.18 ? 47 TRP H CD2 1 ATOM 4497 N NE1 . TRP C 3 47 ? -19.987 50.004 -23.885 1.00 20.55 ? 47 TRP H NE1 1 ATOM 4498 C CE2 . TRP C 3 47 ? -18.921 49.415 -23.233 1.00 17.80 ? 47 TRP H CE2 1 ATOM 4499 C CE3 . TRP C 3 47 ? -18.354 47.311 -22.151 1.00 19.68 ? 47 TRP H CE3 1 ATOM 4500 C CZ2 . TRP C 3 47 ? -17.641 49.921 -23.007 1.00 20.92 ? 47 TRP H CZ2 1 ATOM 4501 C CZ3 . TRP C 3 47 ? -17.094 47.815 -21.923 1.00 24.62 ? 47 TRP H CZ3 1 ATOM 4502 C CH2 . TRP C 3 47 ? -16.760 49.135 -22.306 1.00 20.93 ? 47 TRP H CH2 1 ATOM 4503 N N . MET C 3 48 ? -20.428 45.698 -25.928 1.00 17.12 ? 48 MET H N 1 ATOM 4504 C CA . MET C 3 48 ? -19.244 45.082 -26.581 1.00 17.62 ? 48 MET H CA 1 ATOM 4505 C C . MET C 3 48 ? -17.973 45.863 -26.265 1.00 21.12 ? 48 MET H C 1 ATOM 4506 O O . MET C 3 48 ? -16.890 45.285 -26.145 1.00 21.42 ? 48 MET H O 1 ATOM 4507 C CB . MET C 3 48 ? -19.457 44.959 -28.067 1.00 19.39 ? 48 MET H CB 1 ATOM 4508 C CG . MET C 3 48 ? -20.680 44.020 -28.312 1.00 28.04 ? 48 MET H CG 1 ATOM 4509 S SD . MET C 3 48 ? -20.800 43.875 -30.048 1.00 26.36 ? 48 MET H SD 1 ATOM 4510 C CE . MET C 3 48 ? -19.478 42.543 -30.241 1.00 22.30 ? 48 MET H CE 1 ATOM 4511 N N . GLY C 3 49 ? -18.110 47.188 -26.129 1.00 17.97 ? 49 GLY H N 1 ATOM 4512 C CA . GLY C 3 49 ? -16.924 48.047 -25.964 1.00 16.21 ? 49 GLY H CA 1 ATOM 4513 C C . GLY C 3 49 ? -17.276 49.431 -26.529 1.00 18.06 ? 49 GLY H C 1 ATOM 4514 O O . GLY C 3 49 ? -18.423 49.663 -26.921 1.00 17.20 ? 49 GLY H O 1 ATOM 4515 N N . GLY C 3 50 ? -16.288 50.338 -26.574 1.00 18.20 ? 50 GLY H N 1 ATOM 4516 C CA . GLY C 3 50 ? -16.550 51.665 -27.133 1.00 18.33 ? 50 GLY H CA 1 ATOM 4517 C C . GLY C 3 50 ? -15.259 52.358 -27.546 1.00 17.87 ? 50 GLY H C 1 ATOM 4518 O O . GLY C 3 50 ? -14.159 51.829 -27.384 1.00 18.04 ? 50 GLY H O 1 ATOM 4519 N N . ILE C 3 51 ? -15.417 53.548 -28.123 1.00 15.95 ? 51 ILE H N 1 ATOM 4520 C CA . ILE C 3 51 ? -14.256 54.328 -28.532 1.00 16.92 ? 51 ILE H CA 1 ATOM 4521 C C . ILE C 3 51 ? -14.579 55.804 -28.355 1.00 16.81 ? 51 ILE H C 1 ATOM 4522 O O . ILE C 3 51 ? -15.702 56.247 -28.618 1.00 16.37 ? 51 ILE H O 1 ATOM 4523 C CB . ILE C 3 51 ? -13.855 54.014 -29.969 1.00 17.52 ? 51 ILE H CB 1 ATOM 4524 C CG1 . ILE C 3 51 ? -12.590 54.801 -30.375 1.00 19.22 ? 51 ILE H CG1 1 ATOM 4525 C CG2 . ILE C 3 51 ? -14.959 54.341 -30.992 1.00 18.14 ? 51 ILE H CG2 1 ATOM 4526 C CD1 . ILE C 3 51 ? -11.870 54.071 -31.607 1.00 22.78 ? 51 ILE H CD1 1 ATOM 4527 N N . SER C 3 52 ? -13.554 56.594 -27.991 1.00 17.07 ? 52 SER H N 1 ATOM 4528 C CA . SER C 3 52 ? -13.747 58.037 -27.833 1.00 15.74 ? 52 SER H CA 1 ATOM 4529 C C . SER C 3 52 ? -12.484 58.568 -28.560 1.00 15.22 ? 52 SER H C 1 ATOM 4530 O O . SER C 3 52 ? -11.407 58.590 -27.999 1.00 17.82 ? 52 SER H O 1 ATOM 4531 C CB . SER C 3 52 ? -13.679 58.401 -26.330 1.00 18.78 ? 52 SER H CB 1 ATOM 4532 O OG . SER C 3 52 ? -13.971 59.802 -26.201 1.00 18.77 ? 52 SER H OG 1 ATOM 4533 N N . PRO C 3 53 A -12.631 58.906 -29.841 1.00 18.88 ? 52 PRO H N 1 ATOM 4534 C CA . PRO C 3 53 A -11.433 58.944 -30.714 1.00 19.64 ? 52 PRO H CA 1 ATOM 4535 C C . PRO C 3 53 A -10.521 60.158 -30.550 1.00 21.25 ? 52 PRO H C 1 ATOM 4536 O O . PRO C 3 53 A -9.336 59.988 -30.792 1.00 27.51 ? 52 PRO H O 1 ATOM 4537 C CB . PRO C 3 53 A -12.001 58.902 -32.116 1.00 22.84 ? 52 PRO H CB 1 ATOM 4538 C CG . PRO C 3 53 A -13.335 59.438 -31.993 1.00 20.75 ? 52 PRO H CG 1 ATOM 4539 C CD . PRO C 3 53 A -13.873 58.955 -30.617 1.00 19.83 ? 52 PRO H CD 1 ATOM 4540 N N . ILE C 3 54 ? -11.025 61.322 -30.174 1.00 17.56 ? 53 ILE H N 1 ATOM 4541 C CA . ILE C 3 54 ? -10.103 62.426 -29.889 1.00 20.07 ? 53 ILE H CA 1 ATOM 4542 C C . ILE C 3 54 ? -9.442 62.243 -28.516 1.00 18.27 ? 53 ILE H C 1 ATOM 4543 O O . ILE C 3 54 ? -8.215 62.417 -28.381 1.00 21.69 ? 53 ILE H O 1 ATOM 4544 C CB . ILE C 3 54 ? -10.820 63.792 -29.965 1.00 16.22 ? 53 ILE H CB 1 ATOM 4545 C CG1 . ILE C 3 54 ? -11.336 64.089 -31.386 1.00 18.21 ? 53 ILE H CG1 1 ATOM 4546 C CG2 . ILE C 3 54 ? -9.904 65.031 -29.437 1.00 19.70 ? 53 ILE H CG2 1 ATOM 4547 C CD1 . ILE C 3 54 ? -10.322 64.481 -32.410 1.00 23.73 ? 53 ILE H CD1 1 ATOM 4548 N N . PHE C 3 55 ? -10.245 61.901 -27.531 1.00 17.19 ? 54 PHE H N 1 ATOM 4549 C CA . PHE C 3 55 ? -9.735 61.574 -26.183 1.00 19.69 ? 54 PHE H CA 1 ATOM 4550 C C . PHE C 3 55 ? -8.645 60.523 -26.268 1.00 19.56 ? 54 PHE H C 1 ATOM 4551 O O . PHE C 3 55 ? -7.642 60.568 -25.532 1.00 20.52 ? 54 PHE H O 1 ATOM 4552 C CB . PHE C 3 55 ? -10.923 61.126 -25.295 1.00 17.60 ? 54 PHE H CB 1 ATOM 4553 C CG . PHE C 3 55 ? -10.523 60.742 -23.902 1.00 19.80 ? 54 PHE H CG 1 ATOM 4554 C CD1 . PHE C 3 55 ? -9.808 61.630 -23.118 1.00 20.38 ? 54 PHE H CD1 1 ATOM 4555 C CD2 . PHE C 3 55 ? -10.802 59.477 -23.404 1.00 17.82 ? 54 PHE H CD2 1 ATOM 4556 C CE1 . PHE C 3 55 ? -9.450 61.273 -21.783 1.00 22.53 ? 54 PHE H CE1 1 ATOM 4557 C CE2 . PHE C 3 55 ? -10.401 59.092 -22.138 1.00 23.04 ? 54 PHE H CE2 1 ATOM 4558 C CZ . PHE C 3 55 ? -9.747 59.995 -21.307 1.00 20.74 ? 54 PHE H CZ 1 ATOM 4559 N N . GLY C 3 56 ? -8.843 59.551 -27.163 1.00 19.68 ? 55 GLY H N 1 ATOM 4560 C CA . GLY C 3 56 ? -7.868 58.520 -27.423 1.00 21.23 ? 55 GLY H CA 1 ATOM 4561 C C . GLY C 3 56 ? -8.094 57.175 -26.755 1.00 22.93 ? 55 GLY H C 1 ATOM 4562 O O . GLY C 3 56 ? -7.142 56.412 -26.552 1.00 25.62 ? 55 GLY H O 1 ATOM 4563 N N . SER C 3 57 ? -9.333 56.904 -26.361 1.00 20.90 ? 56 SER H N 1 ATOM 4564 C CA . SER C 3 57 ? -9.638 55.710 -25.601 1.00 18.51 ? 56 SER H CA 1 ATOM 4565 C C . SER C 3 57 ? -10.352 54.699 -26.496 1.00 21.54 ? 56 SER H C 1 ATOM 4566 O O . SER C 3 57 ? -11.293 55.057 -27.199 1.00 19.77 ? 56 SER H O 1 ATOM 4567 C CB . SER C 3 57 ? -10.610 56.074 -24.457 1.00 22.81 ? 56 SER H CB 1 ATOM 4568 O OG . SER C 3 57 ? -11.199 54.889 -23.898 1.00 22.22 ? 56 SER H OG 1 ATOM 4569 N N . THR C 3 58 ? -9.963 53.428 -26.384 1.00 19.72 ? 57 THR H N 1 ATOM 4570 C CA . THR C 3 58 ? -10.833 52.343 -26.898 1.00 19.00 ? 57 THR H CA 1 ATOM 4571 C C . THR C 3 58 ? -11.004 51.358 -25.771 1.00 24.69 ? 57 THR H C 1 ATOM 4572 O O . THR C 3 58 ? -10.009 50.968 -25.132 1.00 27.22 ? 57 THR H O 1 ATOM 4573 C CB . THR C 3 58 ? -10.127 51.628 -28.087 1.00 22.65 ? 57 THR H CB 1 ATOM 4574 O OG1 . THR C 3 58 ? -9.781 52.591 -29.088 1.00 23.73 ? 57 THR H OG1 1 ATOM 4575 C CG2 . THR C 3 58 ? -11.064 50.582 -28.715 1.00 27.45 ? 57 THR H CG2 1 ATOM 4576 N N . ALA C 3 59 ? -12.240 50.954 -25.471 1.00 20.47 ? 58 ALA H N 1 ATOM 4577 C CA . ALA C 3 59 ? -12.453 50.016 -24.376 1.00 20.90 ? 58 ALA H CA 1 ATOM 4578 C C . ALA C 3 59 ? -13.217 48.785 -24.857 1.00 20.42 ? 58 ALA H C 1 ATOM 4579 O O . ALA C 3 59 ? -14.027 48.895 -25.773 1.00 21.64 ? 58 ALA H O 1 ATOM 4580 C CB . ALA C 3 59 ? -13.298 50.673 -23.254 1.00 25.69 ? 58 ALA H CB 1 ATOM 4581 N N . TYR C 3 60 ? -13.003 47.643 -24.199 1.00 19.54 ? 59 TYR H N 1 ATOM 4582 C CA . TYR C 3 60 ? -13.655 46.401 -24.609 1.00 21.06 ? 59 TYR H CA 1 ATOM 4583 C C . TYR C 3 60 ? -14.201 45.693 -23.400 1.00 20.06 ? 59 TYR H C 1 ATOM 4584 O O . TYR C 3 60 ? -13.597 45.718 -22.313 1.00 24.76 ? 59 TYR H O 1 ATOM 4585 C CB . TYR C 3 60 ? -12.606 45.468 -25.215 1.00 21.83 ? 59 TYR H CB 1 ATOM 4586 C CG . TYR C 3 60 ? -12.045 45.993 -26.507 1.00 20.97 ? 59 TYR H CG 1 ATOM 4587 C CD1 . TYR C 3 60 ? -12.806 45.956 -27.648 1.00 22.18 ? 59 TYR H CD1 1 ATOM 4588 C CD2 . TYR C 3 60 ? -10.767 46.539 -26.581 1.00 23.55 ? 59 TYR H CD2 1 ATOM 4589 C CE1 . TYR C 3 60 ? -12.342 46.444 -28.862 1.00 21.47 ? 59 TYR H CE1 1 ATOM 4590 C CE2 . TYR C 3 60 ? -10.272 47.042 -27.787 1.00 25.13 ? 59 TYR H CE2 1 ATOM 4591 C CZ . TYR C 3 60 ? -11.058 46.960 -28.930 1.00 23.86 ? 59 TYR H CZ 1 ATOM 4592 O OH . TYR C 3 60 ? -10.600 47.440 -30.116 1.00 22.32 ? 59 TYR H OH 1 ATOM 4593 N N . ALA C 3 61 ? -15.370 45.079 -23.568 1.00 19.07 ? 60 ALA H N 1 ATOM 4594 C CA . ALA C 3 61 ? -15.884 44.162 -22.575 1.00 19.37 ? 60 ALA H CA 1 ATOM 4595 C C . ALA C 3 61 ? -14.957 42.941 -22.506 1.00 22.31 ? 60 ALA H C 1 ATOM 4596 O O . ALA C 3 61 ? -14.529 42.413 -23.531 1.00 24.62 ? 60 ALA H O 1 ATOM 4597 C CB . ALA C 3 61 ? -17.299 43.690 -22.955 1.00 21.26 ? 60 ALA H CB 1 ATOM 4598 N N . GLN C 3 62 ? -14.680 42.535 -21.282 1.00 27.73 ? 61 GLN H N 1 ATOM 4599 C CA . GLN C 3 62 ? -13.850 41.339 -21.058 1.00 30.21 ? 61 GLN H CA 1 ATOM 4600 C C . GLN C 3 62 ? -14.385 40.150 -21.841 1.00 26.58 ? 61 GLN H C 1 ATOM 4601 O O . GLN C 3 62 ? -13.595 39.386 -22.422 1.00 28.95 ? 61 GLN H O 1 ATOM 4602 C CB . GLN C 3 62 ? -13.882 41.014 -19.549 1.00 30.33 ? 61 GLN H CB 1 ATOM 4603 C CG . GLN C 3 62 ? -13.014 41.968 -18.769 1.00 44.62 ? 61 GLN H CG 1 ATOM 4604 C CD . GLN C 3 62 ? -13.090 41.753 -17.257 1.00 54.80 ? 61 GLN H CD 1 ATOM 4605 O OE1 . GLN C 3 62 ? -13.807 40.869 -16.769 1.00 54.96 ? 61 GLN H OE1 1 ATOM 4606 N NE2 . GLN C 3 62 ? -12.358 42.570 -16.516 1.00 62.10 ? 61 GLN H NE2 1 ATOM 4607 N N . LYS C 3 63 ? -15.706 39.974 -21.866 1.00 27.96 ? 62 LYS H N 1 ATOM 4608 C CA . LYS C 3 63 ? -16.223 38.788 -22.546 1.00 32.21 ? 62 LYS H CA 1 ATOM 4609 C C . LYS C 3 63 ? -15.980 38.754 -24.090 1.00 33.23 ? 62 LYS H C 1 ATOM 4610 O O . LYS C 3 63 ? -16.099 37.710 -24.711 1.00 35.13 ? 62 LYS H O 1 ATOM 4611 C CB . LYS C 3 63 ? -17.682 38.498 -22.171 1.00 40.01 ? 62 LYS H CB 1 ATOM 4612 C CG . LYS C 3 63 ? -18.692 39.354 -22.845 1.00 37.31 ? 62 LYS H CG 1 ATOM 4613 C CD . LYS C 3 63 ? -20.126 39.020 -22.419 1.00 43.90 ? 62 LYS H CD 1 ATOM 4614 C CE . LYS C 3 63 ? -20.775 37.992 -23.324 1.00 41.41 ? 62 LYS H CE 1 ATOM 4615 N NZ . LYS C 3 63 ? -22.271 37.851 -23.088 1.00 42.02 ? 62 LYS H NZ 1 ATOM 4616 N N . PHE C 3 64 ? -15.646 39.906 -24.683 1.00 31.14 ? 63 PHE H N 1 ATOM 4617 C CA . PHE C 3 64 ? -15.321 40.015 -26.131 1.00 26.40 ? 63 PHE H CA 1 ATOM 4618 C C . PHE C 3 64 ? -13.889 40.416 -26.435 1.00 26.79 ? 63 PHE H C 1 ATOM 4619 O O . PHE C 3 64 ? -13.466 40.484 -27.599 1.00 28.55 ? 63 PHE H O 1 ATOM 4620 C CB . PHE C 3 64 ? -16.211 41.086 -26.780 1.00 27.85 ? 63 PHE H CB 1 ATOM 4621 C CG . PHE C 3 64 ? -17.648 40.714 -26.836 1.00 28.84 ? 63 PHE H CG 1 ATOM 4622 C CD1 . PHE C 3 64 ? -18.101 39.756 -27.727 1.00 28.51 ? 63 PHE H CD1 1 ATOM 4623 C CD2 . PHE C 3 64 ? -18.540 41.295 -25.988 1.00 24.46 ? 63 PHE H CD2 1 ATOM 4624 C CE1 . PHE C 3 64 ? -19.467 39.437 -27.771 1.00 28.78 ? 63 PHE H CE1 1 ATOM 4625 C CE2 . PHE C 3 64 ? -19.893 40.984 -26.007 1.00 25.53 ? 63 PHE H CE2 1 ATOM 4626 C CZ . PHE C 3 64 ? -20.365 40.071 -26.921 1.00 27.93 ? 63 PHE H CZ 1 ATOM 4627 N N . GLN C 3 65 ? -13.126 40.685 -25.390 1.00 32.98 ? 64 GLN H N 1 ATOM 4628 C CA . GLN C 3 65 ? -11.742 41.061 -25.554 1.00 36.95 ? 64 GLN H CA 1 ATOM 4629 C C . GLN C 3 65 ? -11.017 40.023 -26.461 1.00 34.90 ? 64 GLN H C 1 ATOM 4630 O O . GLN C 3 65 ? -11.156 38.815 -26.315 1.00 35.48 ? 64 GLN H O 1 ATOM 4631 C CB . GLN C 3 65 ? -11.094 41.196 -24.156 1.00 42.74 ? 64 GLN H CB 1 ATOM 4632 C CG . GLN C 3 65 ? -9.660 41.664 -24.183 1.00 58.59 ? 64 GLN H CG 1 ATOM 4633 C CD . GLN C 3 65 ? -9.548 43.171 -24.255 1.00 67.94 ? 64 GLN H CD 1 ATOM 4634 O OE1 . GLN C 3 65 ? -10.001 43.882 -23.351 1.00 74.23 ? 64 GLN H OE1 1 ATOM 4635 N NE2 . GLN C 3 65 ? -8.932 43.671 -25.327 1.00 69.34 ? 64 GLN H NE2 1 ATOM 4636 N N . GLY C 3 66 ? -10.304 40.529 -27.453 1.00 33.35 ? 65 GLY H N 1 ATOM 4637 C CA . GLY C 3 66 ? -9.559 39.660 -28.321 1.00 37.26 ? 65 GLY H CA 1 ATOM 4638 C C . GLY C 3 66 ? -10.304 39.238 -29.563 1.00 35.64 ? 65 GLY H C 1 ATOM 4639 O O . GLY C 3 66 ? -9.644 38.826 -30.523 1.00 43.87 ? 65 GLY H O 1 ATOM 4640 N N . ARG C 3 67 ? -11.641 39.272 -29.543 1.00 25.12 ? 66 ARG H N 1 ATOM 4641 C CA . ARG C 3 67 ? -12.403 38.859 -30.700 1.00 26.35 ? 66 ARG H CA 1 ATOM 4642 C C . ARG C 3 67 ? -13.016 40.044 -31.436 1.00 26.21 ? 66 ARG H C 1 ATOM 4643 O O . ARG C 3 67 ? -13.412 39.930 -32.563 1.00 23.00 ? 66 ARG H O 1 ATOM 4644 C CB . ARG C 3 67 ? -13.523 37.936 -30.282 1.00 25.83 ? 66 ARG H CB 1 ATOM 4645 C CG . ARG C 3 67 ? -14.011 37.158 -31.474 1.00 34.38 ? 66 ARG H CG 1 ATOM 4646 C CD . ARG C 3 67 ? -14.674 35.850 -31.092 1.00 29.65 ? 66 ARG H CD 1 ATOM 4647 N NE . ARG C 3 67 ? -15.852 36.006 -30.266 1.00 23.88 ? 66 ARG H NE 1 ATOM 4648 C CZ . ARG C 3 67 ? -17.098 35.992 -30.772 1.00 19.96 ? 66 ARG H CZ 1 ATOM 4649 N NH1 . ARG C 3 67 ? -17.277 35.929 -32.095 1.00 21.93 ? 66 ARG H NH1 1 ATOM 4650 N NH2 . ARG C 3 67 ? -18.147 36.057 -29.949 1.00 22.76 ? 66 ARG H NH2 1 ATOM 4651 N N . VAL C 3 68 ? -13.100 41.183 -30.754 1.00 19.85 ? 67 VAL H N 1 ATOM 4652 C CA . VAL C 3 68 ? -13.702 42.366 -31.367 1.00 19.35 ? 67 VAL H CA 1 ATOM 4653 C C . VAL C 3 68 ? -12.630 43.482 -31.493 1.00 21.70 ? 67 VAL H C 1 ATOM 4654 O O . VAL C 3 68 ? -11.749 43.632 -30.618 1.00 22.99 ? 67 VAL H O 1 ATOM 4655 C CB . VAL C 3 68 ? -14.982 42.862 -30.600 1.00 29.41 ? 67 VAL H CB 1 ATOM 4656 C CG1 . VAL C 3 68 ? -14.623 43.396 -29.271 1.00 23.96 ? 67 VAL H CG1 1 ATOM 4657 C CG2 . VAL C 3 68 ? -15.695 44.004 -31.398 1.00 25.24 ? 67 VAL H CG2 1 ATOM 4658 N N . THR C 3 69 ? -12.695 44.214 -32.603 1.00 21.55 ? 68 THR H N 1 ATOM 4659 C CA . THR C 3 69 ? -11.841 45.386 -32.791 1.00 22.29 ? 68 THR H CA 1 ATOM 4660 C C . THR C 3 69 ? -12.745 46.599 -33.043 1.00 19.11 ? 68 THR H C 1 ATOM 4661 O O . THR C 3 69 ? -13.543 46.580 -33.960 1.00 19.69 ? 68 THR H O 1 ATOM 4662 C CB . THR C 3 69 ? -10.882 45.228 -33.955 1.00 24.62 ? 68 THR H CB 1 ATOM 4663 O OG1 . THR C 3 69 ? -10.031 44.090 -33.664 1.00 25.18 ? 68 THR H OG1 1 ATOM 4664 C CG2 . THR C 3 69 ? -10.009 46.504 -34.081 1.00 26.26 ? 68 THR H CG2 1 ATOM 4665 N N . ILE C 3 70 ? -12.632 47.637 -32.209 1.00 17.47 ? 69 ILE H N 1 ATOM 4666 C CA . ILE C 3 70 ? -13.450 48.827 -32.412 1.00 18.28 ? 69 ILE H CA 1 ATOM 4667 C C . ILE C 3 70 ? -12.485 49.954 -32.837 1.00 20.11 ? 69 ILE H C 1 ATOM 4668 O O . ILE C 3 70 ? -11.341 50.042 -32.335 1.00 23.07 ? 69 ILE H O 1 ATOM 4669 C CB . ILE C 3 70 ? -14.180 49.160 -31.073 1.00 20.50 ? 69 ILE H CB 1 ATOM 4670 C CG1 . ILE C 3 70 ? -15.284 48.113 -30.862 1.00 19.78 ? 69 ILE H CG1 1 ATOM 4671 C CG2 . ILE C 3 70 ? -14.853 50.625 -31.115 1.00 19.39 ? 69 ILE H CG2 1 ATOM 4672 C CD1 . ILE C 3 70 ? -15.851 48.193 -29.404 1.00 20.26 ? 69 ILE H CD1 1 ATOM 4673 N N . SER C 3 71 ? -12.919 50.751 -33.784 1.00 17.74 ? 70 SER H N 1 ATOM 4674 C CA . SER C 3 71 ? -12.042 51.753 -34.378 1.00 19.89 ? 70 SER H CA 1 ATOM 4675 C C . SER C 3 71 ? -12.864 52.944 -34.833 1.00 20.45 ? 70 SER H C 1 ATOM 4676 O O . SER C 3 71 ? -14.104 52.925 -34.783 1.00 19.91 ? 70 SER H O 1 ATOM 4677 C CB . SER C 3 71 ? -11.217 51.191 -35.524 1.00 21.58 ? 70 SER H CB 1 ATOM 4678 O OG . SER C 3 71 ? -12.042 50.709 -36.614 1.00 20.56 ? 70 SER H OG 1 ATOM 4679 N N . ALA C 3 72 ? -12.175 54.001 -35.263 1.00 18.35 ? 71 ALA H N 1 ATOM 4680 C CA . ALA C 3 72 ? -12.892 55.190 -35.732 1.00 18.91 ? 71 ALA H CA 1 ATOM 4681 C C . ALA C 3 72 ? -12.097 55.944 -36.757 1.00 22.89 ? 71 ALA H C 1 ATOM 4682 O O . ALA C 3 72 ? -10.884 55.905 -36.736 1.00 23.35 ? 71 ALA H O 1 ATOM 4683 C CB . ALA C 3 72 ? -13.197 56.141 -34.547 1.00 23.14 ? 71 ALA H CB 1 ATOM 4684 N N . ASP C 3 73 ? -12.795 56.645 -37.636 1.00 20.28 ? 72 ASP H N 1 ATOM 4685 C CA . ASP C 3 73 ? -12.124 57.521 -38.618 1.00 23.73 ? 72 ASP H CA 1 ATOM 4686 C C . ASP C 3 73 ? -12.640 58.928 -38.311 1.00 21.97 ? 72 ASP H C 1 ATOM 4687 O O . ASP C 3 73 ? -13.806 59.250 -38.582 1.00 22.59 ? 72 ASP H O 1 ATOM 4688 C CB . ASP C 3 73 ? -12.558 57.042 -39.986 1.00 25.21 ? 72 ASP H CB 1 ATOM 4689 C CG . ASP C 3 73 ? -11.963 57.862 -41.104 1.00 36.84 ? 72 ASP H CG 1 ATOM 4690 O OD1 . ASP C 3 73 ? -11.426 58.975 -40.829 1.00 26.46 ? 72 ASP H OD1 1 ATOM 4691 O OD2 . ASP C 3 73 ? -12.044 57.377 -42.249 1.00 38.17 ? 72 ASP H OD2 1 ATOM 4692 N N . ILE C 3 74 ? -11.811 59.777 -37.679 1.00 20.34 ? 73 ILE H N 1 ATOM 4693 C CA . ILE C 3 74 ? -12.355 61.051 -37.279 1.00 20.31 ? 73 ILE H CA 1 ATOM 4694 C C . ILE C 3 74 ? -12.671 61.901 -38.508 1.00 23.73 ? 73 ILE H C 1 ATOM 4695 O O . ILE C 3 74 ? -13.424 62.838 -38.389 1.00 22.53 ? 73 ILE H O 1 ATOM 4696 C CB . ILE C 3 74 ? -11.469 61.837 -36.331 1.00 24.88 ? 73 ILE H CB 1 ATOM 4697 C CG1 . ILE C 3 74 ? -10.087 61.996 -36.944 1.00 22.98 ? 73 ILE H CG1 1 ATOM 4698 C CG2 . ILE C 3 74 ? -11.286 61.079 -34.987 1.00 24.90 ? 73 ILE H CG2 1 ATOM 4699 C CD1 . ILE C 3 74 ? -9.238 63.076 -36.138 1.00 24.07 ? 73 ILE H CD1 1 ATOM 4700 N N . PHE C 3 75 ? -12.043 61.624 -39.647 1.00 21.47 ? 74 PHE H N 1 ATOM 4701 C CA . PHE C 3 75 ? -12.225 62.498 -40.807 1.00 20.03 ? 74 PHE H CA 1 ATOM 4702 C C . PHE C 3 75 ? -13.525 62.246 -41.546 1.00 25.38 ? 74 PHE H C 1 ATOM 4703 O O . PHE C 3 75 ? -14.064 63.154 -42.172 1.00 28.64 ? 74 PHE H O 1 ATOM 4704 C CB . PHE C 3 75 ? -11.023 62.368 -41.774 1.00 21.53 ? 74 PHE H CB 1 ATOM 4705 C CG . PHE C 3 75 ? -9.718 62.508 -41.079 1.00 24.86 ? 74 PHE H CG 1 ATOM 4706 C CD1 . PHE C 3 75 ? -9.343 63.727 -40.552 1.00 29.21 ? 74 PHE H CD1 1 ATOM 4707 C CD2 . PHE C 3 75 ? -8.864 61.409 -40.959 1.00 30.48 ? 74 PHE H CD2 1 ATOM 4708 C CE1 . PHE C 3 75 ? -8.100 63.844 -39.910 1.00 30.66 ? 74 PHE H CE1 1 ATOM 4709 C CE2 . PHE C 3 75 ? -7.646 61.507 -40.303 1.00 30.31 ? 74 PHE H CE2 1 ATOM 4710 C CZ . PHE C 3 75 ? -7.272 62.758 -39.783 1.00 25.10 ? 74 PHE H CZ 1 ATOM 4711 N N . SER C 3 76 ? -14.072 61.036 -41.440 1.00 22.89 ? 75 SER H N 1 ATOM 4712 C CA . SER C 3 76 ? -15.386 60.742 -42.035 1.00 23.33 ? 75 SER H CA 1 ATOM 4713 C C . SER C 3 76 ? -16.462 60.657 -40.961 1.00 22.58 ? 75 SER H C 1 ATOM 4714 O O . SER C 3 76 ? -17.597 60.223 -41.245 1.00 24.49 ? 75 SER H O 1 ATOM 4715 C CB . SER C 3 76 ? -15.305 59.400 -42.787 1.00 24.53 ? 75 SER H CB 1 ATOM 4716 O OG . SER C 3 76 ? -15.045 58.373 -41.856 1.00 27.40 ? 75 SER H OG 1 ATOM 4717 N N . ASN C 3 77 ? -16.094 60.995 -39.715 1.00 19.47 ? 76 ASN H N 1 ATOM 4718 C CA . ASN C 3 77 ? -17.058 60.932 -38.618 1.00 20.11 ? 76 ASN H CA 1 ATOM 4719 C C . ASN C 3 77 ? -17.702 59.543 -38.501 1.00 20.49 ? 76 ASN H C 1 ATOM 4720 O O . ASN C 3 77 ? -18.905 59.420 -38.242 1.00 23.74 ? 76 ASN H O 1 ATOM 4721 C CB . ASN C 3 77 ? -18.153 61.979 -38.787 1.00 21.10 ? 76 ASN H CB 1 ATOM 4722 C CG . ASN C 3 77 ? -17.618 63.411 -38.573 1.00 27.53 ? 76 ASN H CG 1 ATOM 4723 O OD1 . ASN C 3 77 ? -16.714 63.660 -37.773 1.00 22.86 ? 76 ASN H OD1 1 ATOM 4724 N ND2 . ASN C 3 77 ? -18.207 64.356 -39.273 1.00 43.59 ? 76 ASN H ND2 1 ATOM 4725 N N . THR C 3 78 ? -16.891 58.505 -38.615 1.00 18.31 ? 77 THR H N 1 ATOM 4726 C CA . THR C 3 78 ? -17.481 57.139 -38.596 1.00 21.23 ? 77 THR H CA 1 ATOM 4727 C C . THR C 3 78 ? -16.785 56.278 -37.545 1.00 20.58 ? 77 THR H C 1 ATOM 4728 O O . THR C 3 78 ? -15.563 56.367 -37.383 1.00 22.67 ? 77 THR H O 1 ATOM 4729 C CB . THR C 3 78 ? -17.300 56.493 -39.974 1.00 23.24 ? 77 THR H CB 1 ATOM 4730 O OG1 . THR C 3 78 ? -17.952 57.324 -40.943 1.00 23.78 ? 77 THR H OG1 1 ATOM 4731 C CG2 . THR C 3 78 ? -17.989 55.087 -40.042 1.00 23.29 ? 77 THR H CG2 1 ATOM 4732 N N . ALA C 3 79 ? -17.545 55.447 -36.828 1.00 18.28 ? 78 ALA H N 1 ATOM 4733 C CA . ALA C 3 79 ? -16.980 54.478 -35.893 1.00 18.34 ? 78 ALA H CA 1 ATOM 4734 C C . ALA C 3 79 ? -17.250 53.080 -36.471 1.00 17.81 ? 78 ALA H C 1 ATOM 4735 O O . ALA C 3 79 ? -18.211 52.901 -37.252 1.00 18.95 ? 78 ALA H O 1 ATOM 4736 C CB . ALA C 3 79 ? -17.709 54.618 -34.523 1.00 20.11 ? 78 ALA H CB 1 ATOM 4737 N N . TYR C 3 80 ? -16.442 52.114 -36.082 1.00 17.83 ? 79 TYR H N 1 ATOM 4738 C CA . TYR C 3 80 ? -16.597 50.771 -36.669 1.00 21.06 ? 79 TYR H CA 1 ATOM 4739 C C . TYR C 3 80 ? -16.473 49.713 -35.558 1.00 19.84 ? 79 TYR H C 1 ATOM 4740 O O . TYR C 3 80 ? -15.764 49.910 -34.540 1.00 19.40 ? 79 TYR H O 1 ATOM 4741 C CB . TYR C 3 80 ? -15.463 50.447 -37.627 1.00 16.83 ? 79 TYR H CB 1 ATOM 4742 C CG . TYR C 3 80 ? -15.357 51.371 -38.809 1.00 20.91 ? 79 TYR H CG 1 ATOM 4743 C CD1 . TYR C 3 80 ? -16.077 51.135 -39.952 1.00 23.13 ? 79 TYR H CD1 1 ATOM 4744 C CD2 . TYR C 3 80 ? -14.546 52.509 -38.734 1.00 24.62 ? 79 TYR H CD2 1 ATOM 4745 C CE1 . TYR C 3 80 ? -16.005 52.003 -41.033 1.00 23.35 ? 79 TYR H CE1 1 ATOM 4746 C CE2 . TYR C 3 80 ? -14.504 53.411 -39.799 1.00 28.82 ? 79 TYR H CE2 1 ATOM 4747 C CZ . TYR C 3 80 ? -15.218 53.131 -40.933 1.00 24.49 ? 79 TYR H CZ 1 ATOM 4748 O OH . TYR C 3 80 ? -15.159 54.006 -42.004 1.00 29.56 ? 79 TYR H OH 1 ATOM 4749 N N . MET C 3 81 ? -17.109 48.559 -35.791 1.00 17.87 ? 80 MET H N 1 ATOM 4750 C CA . MET C 3 81 ? -16.957 47.408 -34.903 1.00 16.35 ? 80 MET H CA 1 ATOM 4751 C C . MET C 3 81 ? -16.695 46.200 -35.845 1.00 19.47 ? 80 MET H C 1 ATOM 4752 O O . MET C 3 81 ? -17.459 45.955 -36.745 1.00 19.93 ? 80 MET H O 1 ATOM 4753 C CB . MET C 3 81 ? -18.275 47.141 -34.132 1.00 16.91 ? 80 MET H CB 1 ATOM 4754 C CG . MET C 3 81 ? -18.133 46.187 -32.987 1.00 23.53 ? 80 MET H CG 1 ATOM 4755 S SD . MET C 3 81 ? -18.339 44.498 -33.629 1.00 31.75 ? 80 MET H SD 1 ATOM 4756 C CE . MET C 3 81 ? -19.884 44.469 -34.573 1.00 28.22 ? 80 MET H CE 1 ATOM 4757 N N . GLU C 3 82 ? -15.587 45.490 -35.623 1.00 17.60 ? 81 GLU H N 1 ATOM 4758 C CA . GLU C 3 82 ? -15.326 44.290 -36.406 1.00 18.62 ? 81 GLU H CA 1 ATOM 4759 C C . GLU C 3 82 ? -15.320 43.113 -35.449 1.00 19.92 ? 81 GLU H C 1 ATOM 4760 O O . GLU C 3 82 ? -14.574 43.123 -34.474 1.00 22.98 ? 81 GLU H O 1 ATOM 4761 C CB . GLU C 3 82 ? -13.943 44.414 -37.092 1.00 22.96 ? 81 GLU H CB 1 ATOM 4762 C CG . GLU C 3 82 ? -13.545 43.143 -37.901 1.00 23.59 ? 81 GLU H CG 1 ATOM 4763 C CD . GLU C 3 82 ? -12.389 43.532 -38.874 1.00 35.61 ? 81 GLU H CD 1 ATOM 4764 O OE1 . GLU C 3 82 ? -11.354 44.004 -38.369 1.00 32.94 ? 81 GLU H OE1 1 ATOM 4765 O OE2 . GLU C 3 82 ? -12.522 43.387 -40.103 1.00 47.31 ? 81 GLU H OE2 1 ATOM 4766 N N . LEU C 3 83 ? -16.166 42.101 -35.698 1.00 18.19 ? 82 LEU H N 1 ATOM 4767 C CA . LEU C 3 83 ? -16.237 40.947 -34.786 1.00 17.63 ? 82 LEU H CA 1 ATOM 4768 C C . LEU C 3 83 ? -15.748 39.748 -35.605 1.00 18.63 ? 82 LEU H C 1 ATOM 4769 O O . LEU C 3 83 ? -16.296 39.506 -36.688 1.00 21.19 ? 82 LEU H O 1 ATOM 4770 C CB . LEU C 3 83 ? -17.703 40.761 -34.349 1.00 20.36 ? 82 LEU H CB 1 ATOM 4771 C CG . LEU C 3 83 ? -17.931 39.590 -33.375 1.00 19.61 ? 82 LEU H CG 1 ATOM 4772 C CD1 . LEU C 3 83 ? -17.214 39.757 -32.013 1.00 23.19 ? 82 LEU H CD1 1 ATOM 4773 C CD2 . LEU C 3 83 ? -19.423 39.459 -33.139 1.00 21.78 ? 82 LEU H CD2 1 ATOM 4774 N N . ASN C 3 84 A -14.777 39.016 -35.057 1.00 18.74 ? 82 ASN H N 1 ATOM 4775 C CA . ASN C 3 84 A -14.129 37.920 -35.819 1.00 18.40 ? 82 ASN H CA 1 ATOM 4776 C C . ASN C 3 84 A -14.642 36.562 -35.339 1.00 19.79 ? 82 ASN H C 1 ATOM 4777 O O . ASN C 3 84 A -15.287 36.410 -34.302 1.00 21.21 ? 82 ASN H O 1 ATOM 4778 C CB . ASN C 3 84 A -12.636 38.052 -35.596 1.00 22.22 ? 82 ASN H CB 1 ATOM 4779 C CG . ASN C 3 84 A -12.111 39.416 -36.094 1.00 30.12 ? 82 ASN H CG 1 ATOM 4780 O OD1 . ASN C 3 84 A -12.165 39.719 -37.309 1.00 35.25 ? 82 ASN H OD1 1 ATOM 4781 N ND2 . ASN C 3 84 A -11.664 40.264 -35.159 1.00 33.98 ? 82 ASN H ND2 1 ATOM 4782 N N . SER C 3 85 B -14.262 35.530 -36.088 1.00 22.92 ? 82 SER H N 1 ATOM 4783 C CA . SER C 3 85 B -14.629 34.154 -35.702 1.00 23.62 ? 82 SER H CA 1 ATOM 4784 C C . SER C 3 85 B -16.109 33.937 -35.378 1.00 17.90 ? 82 SER H C 1 ATOM 4785 O O . SER C 3 85 B -16.434 33.327 -34.338 1.00 22.34 ? 82 SER H O 1 ATOM 4786 C CB . SER C 3 85 B -13.739 33.629 -34.566 1.00 26.34 ? 82 SER H CB 1 ATOM 4787 O OG . SER C 3 85 B -12.371 33.724 -34.960 1.00 29.12 ? 82 SER H OG 1 ATOM 4788 N N . LEU C 3 86 C -16.982 34.398 -36.267 1.00 19.38 ? 82 LEU H N 1 ATOM 4789 C CA . LEU C 3 86 C -18.422 34.398 -36.033 1.00 19.22 ? 82 LEU H CA 1 ATOM 4790 C C . LEU C 3 86 C -19.010 32.985 -35.876 1.00 25.16 ? 82 LEU H C 1 ATOM 4791 O O . LEU C 3 86 C -18.622 32.042 -36.612 1.00 23.02 ? 82 LEU H O 1 ATOM 4792 C CB . LEU C 3 86 C -19.173 35.147 -37.146 1.00 19.69 ? 82 LEU H CB 1 ATOM 4793 C CG . LEU C 3 86 C -18.863 36.654 -37.249 1.00 21.32 ? 82 LEU H CG 1 ATOM 4794 C CD1 . LEU C 3 86 C -19.370 37.156 -38.566 1.00 19.62 ? 82 LEU H CD1 1 ATOM 4795 C CD2 . LEU C 3 86 C -19.561 37.364 -36.052 1.00 18.78 ? 82 LEU H CD2 1 ATOM 4796 N N . THR C 3 87 ? -19.916 32.825 -34.922 1.00 21.31 ? 83 THR H N 1 ATOM 4797 C CA . THR C 3 87 ? -20.752 31.594 -34.853 1.00 22.14 ? 83 THR H CA 1 ATOM 4798 C C . THR C 3 87 ? -22.210 32.014 -34.736 1.00 28.84 ? 83 THR H C 1 ATOM 4799 O O . THR C 3 87 ? -22.525 33.223 -34.663 1.00 22.41 ? 83 THR H O 1 ATOM 4800 C CB . THR C 3 87 ? -20.381 30.698 -33.669 1.00 27.90 ? 83 THR H CB 1 ATOM 4801 O OG1 . THR C 3 87 ? -20.844 31.310 -32.454 1.00 24.08 ? 83 THR H OG1 1 ATOM 4802 C CG2 . THR C 3 87 ? -18.816 30.470 -33.545 1.00 22.55 ? 83 THR H CG2 1 ATOM 4803 N N . SER C 3 88 ? -23.121 31.029 -34.650 1.00 23.48 ? 84 SER H N 1 ATOM 4804 C CA . SER C 3 88 ? -24.520 31.370 -34.528 1.00 25.32 ? 84 SER H CA 1 ATOM 4805 C C . SER C 3 88 ? -24.817 32.138 -33.215 1.00 21.85 ? 84 SER H C 1 ATOM 4806 O O . SER C 3 88 ? -25.892 32.744 -33.110 1.00 25.12 ? 84 SER H O 1 ATOM 4807 C CB . SER C 3 88 ? -25.401 30.097 -34.584 1.00 27.67 ? 84 SER H CB 1 ATOM 4808 O OG . SER C 3 88 ? -25.164 29.272 -33.460 1.00 30.24 ? 84 SER H OG 1 ATOM 4809 N N . GLU C 3 89 ? -23.936 32.029 -32.225 1.00 20.16 ? 85 GLU H N 1 ATOM 4810 C CA . GLU C 3 89 ? -24.083 32.793 -30.967 1.00 21.69 ? 85 GLU H CA 1 ATOM 4811 C C . GLU C 3 89 ? -23.947 34.303 -31.227 1.00 23.22 ? 85 GLU H C 1 ATOM 4812 O O . GLU C 3 89 ? -24.326 35.098 -30.370 1.00 21.72 ? 85 GLU H O 1 ATOM 4813 C CB . GLU C 3 89 ? -23.051 32.352 -29.912 1.00 23.57 ? 85 GLU H CB 1 ATOM 4814 C CG . GLU C 3 89 ? -23.346 30.887 -29.427 1.00 26.20 ? 85 GLU H CG 1 ATOM 4815 C CD . GLU C 3 89 ? -22.270 30.332 -28.503 1.00 37.02 ? 85 GLU H CD 1 ATOM 4816 O OE1 . GLU C 3 89 ? -22.241 29.097 -28.322 1.00 40.87 ? 85 GLU H OE1 1 ATOM 4817 O OE2 . GLU C 3 89 ? -21.464 31.105 -27.949 1.00 44.78 ? 85 GLU H OE2 1 ATOM 4818 N N . ASP C 3 90 ? -23.417 34.682 -32.378 1.00 20.23 ? 86 ASP H N 1 ATOM 4819 C CA . ASP C 3 90 ? -23.251 36.117 -32.702 1.00 20.47 ? 86 ASP H CA 1 ATOM 4820 C C . ASP C 3 90 ? -24.372 36.645 -33.543 1.00 21.46 ? 86 ASP H C 1 ATOM 4821 O O . ASP C 3 90 ? -24.397 37.816 -33.909 1.00 20.83 ? 86 ASP H O 1 ATOM 4822 C CB . ASP C 3 90 ? -21.927 36.343 -33.427 1.00 20.76 ? 86 ASP H CB 1 ATOM 4823 C CG . ASP C 3 90 ? -20.731 35.881 -32.567 1.00 25.53 ? 86 ASP H CG 1 ATOM 4824 O OD1 . ASP C 3 90 ? -20.637 36.325 -31.390 1.00 21.00 ? 86 ASP H OD1 1 ATOM 4825 O OD2 . ASP C 3 90 ? -19.861 35.090 -33.029 1.00 20.51 ? 86 ASP H OD2 1 ATOM 4826 N N . THR C 3 91 ? -25.316 35.784 -33.919 1.00 17.35 ? 87 THR H N 1 ATOM 4827 C CA . THR C 3 91 ? -26.484 36.300 -34.632 1.00 16.88 ? 87 THR H CA 1 ATOM 4828 C C . THR C 3 91 ? -27.242 37.242 -33.651 1.00 21.59 ? 87 THR H C 1 ATOM 4829 O O . THR C 3 91 ? -27.590 36.809 -32.561 1.00 21.11 ? 87 THR H O 1 ATOM 4830 C CB . THR C 3 91 ? -27.426 35.123 -35.030 1.00 23.76 ? 87 THR H CB 1 ATOM 4831 O OG1 . THR C 3 91 ? -26.771 34.380 -36.077 1.00 20.95 ? 87 THR H OG1 1 ATOM 4832 C CG2 . THR C 3 91 ? -28.753 35.669 -35.572 1.00 20.50 ? 87 THR H CG2 1 ATOM 4833 N N . ALA C 3 92 ? -27.453 38.485 -34.078 1.00 20.39 ? 88 ALA H N 1 ATOM 4834 C CA . ALA C 3 92 ? -27.926 39.576 -33.158 1.00 19.24 ? 88 ALA H CA 1 ATOM 4835 C C . ALA C 3 92 ? -28.138 40.832 -33.951 1.00 21.04 ? 88 ALA H C 1 ATOM 4836 O O . ALA C 3 92 ? -27.674 40.960 -35.126 1.00 20.99 ? 88 ALA H O 1 ATOM 4837 C CB . ALA C 3 92 ? -26.866 39.809 -32.037 1.00 16.04 ? 88 ALA H CB 1 ATOM 4838 N N . VAL C 3 93 ? -28.775 41.828 -33.320 1.00 18.58 ? 89 VAL H N 1 ATOM 4839 C CA . VAL C 3 93 ? -28.800 43.141 -33.910 1.00 15.44 ? 89 VAL H CA 1 ATOM 4840 C C . VAL C 3 93 ? -27.723 43.916 -33.164 1.00 18.91 ? 89 VAL H C 1 ATOM 4841 O O . VAL C 3 93 ? -27.572 43.786 -31.930 1.00 18.60 ? 89 VAL H O 1 ATOM 4842 C CB . VAL C 3 93 ? -30.168 43.836 -33.651 1.00 22.37 ? 89 VAL H CB 1 ATOM 4843 C CG1 . VAL C 3 93 ? -30.078 45.302 -34.150 1.00 22.75 ? 89 VAL H CG1 1 ATOM 4844 C CG2 . VAL C 3 93 ? -31.259 43.044 -34.393 1.00 25.69 ? 89 VAL H CG2 1 ATOM 4845 N N . TYR C 3 94 ? -26.893 44.647 -33.907 1.00 16.26 ? 90 TYR H N 1 ATOM 4846 C CA . TYR C 3 94 ? -25.771 45.363 -33.279 1.00 17.05 ? 90 TYR H CA 1 ATOM 4847 C C . TYR C 3 94 ? -26.114 46.873 -33.383 1.00 17.25 ? 90 TYR H C 1 ATOM 4848 O O . TYR C 3 94 ? -26.404 47.357 -34.488 1.00 18.74 ? 90 TYR H O 1 ATOM 4849 C CB . TYR C 3 94 ? -24.463 45.074 -34.067 1.00 15.75 ? 90 TYR H CB 1 ATOM 4850 C CG . TYR C 3 94 ? -24.002 43.679 -33.798 1.00 16.56 ? 90 TYR H CG 1 ATOM 4851 C CD1 . TYR C 3 94 ? -23.004 43.412 -32.877 1.00 20.72 ? 90 TYR H CD1 1 ATOM 4852 C CD2 . TYR C 3 94 ? -24.626 42.584 -34.461 1.00 20.77 ? 90 TYR H CD2 1 ATOM 4853 C CE1 . TYR C 3 94 ? -22.603 42.077 -32.584 1.00 19.77 ? 90 TYR H CE1 1 ATOM 4854 C CE2 . TYR C 3 94 ? -24.230 41.256 -34.154 1.00 17.80 ? 90 TYR H CE2 1 ATOM 4855 C CZ . TYR C 3 94 ? -23.257 41.022 -33.242 1.00 19.06 ? 90 TYR H CZ 1 ATOM 4856 O OH . TYR C 3 94 ? -22.831 39.740 -32.906 1.00 19.22 ? 90 TYR H OH 1 ATOM 4857 N N . PHE C 3 95 ? -26.035 47.604 -32.253 1.00 18.02 ? 91 PHE H N 1 ATOM 4858 C CA . PHE C 3 95 ? -26.331 49.050 -32.276 1.00 17.45 ? 91 PHE H CA 1 ATOM 4859 C C . PHE C 3 95 ? -25.078 49.815 -31.930 1.00 18.14 ? 91 PHE H C 1 ATOM 4860 O O . PHE C 3 95 ? -24.267 49.332 -31.119 1.00 16.94 ? 91 PHE H O 1 ATOM 4861 C CB . PHE C 3 95 ? -27.302 49.416 -31.130 1.00 15.53 ? 91 PHE H CB 1 ATOM 4862 C CG . PHE C 3 95 ? -28.672 48.816 -31.289 1.00 17.56 ? 91 PHE H CG 1 ATOM 4863 C CD1 . PHE C 3 95 ? -29.603 49.414 -32.140 1.00 18.02 ? 91 PHE H CD1 1 ATOM 4864 C CD2 . PHE C 3 95 ? -29.008 47.650 -30.574 1.00 19.02 ? 91 PHE H CD2 1 ATOM 4865 C CE1 . PHE C 3 95 ? -30.935 48.859 -32.310 1.00 16.95 ? 91 PHE H CE1 1 ATOM 4866 C CE2 . PHE C 3 95 ? -30.279 47.097 -30.720 1.00 18.66 ? 91 PHE H CE2 1 ATOM 4867 C CZ . PHE C 3 95 ? -31.230 47.677 -31.574 1.00 19.43 ? 91 PHE H CZ 1 ATOM 4868 N N . CYS C 3 96 ? -24.913 50.978 -32.562 1.00 16.73 ? 92 CYS H N 1 ATOM 4869 C CA . CYS C 3 96 ? -23.960 51.944 -32.015 1.00 17.29 ? 92 CYS H CA 1 ATOM 4870 C C . CYS C 3 96 ? -24.723 52.988 -31.238 1.00 17.06 ? 92 CYS H C 1 ATOM 4871 O O . CYS C 3 96 ? -25.875 53.263 -31.554 1.00 18.60 ? 92 CYS H O 1 ATOM 4872 C CB . CYS C 3 96 ? -23.112 52.578 -33.110 1.00 16.96 ? 92 CYS H CB 1 ATOM 4873 S SG . CYS C 3 96 ? -24.073 53.550 -34.302 1.00 23.04 ? 92 CYS H SG 1 ATOM 4874 N N . ALA C 3 97 ? -24.106 53.535 -30.177 1.00 16.55 ? 93 ALA H N 1 ATOM 4875 C CA . ALA C 3 97 ? -24.851 54.544 -29.384 1.00 15.41 ? 93 ALA H CA 1 ATOM 4876 C C . ALA C 3 97 ? -23.837 55.532 -28.837 1.00 19.27 ? 93 ALA H C 1 ATOM 4877 O O . ALA C 3 97 ? -22.745 55.155 -28.370 1.00 20.43 ? 93 ALA H O 1 ATOM 4878 C CB . ALA C 3 97 ? -25.556 53.905 -28.215 1.00 19.94 ? 93 ALA H CB 1 ATOM 4879 N N . ARG C 3 98 ? -24.256 56.805 -28.836 1.00 19.30 ? 94 ARG H N 1 ATOM 4880 C CA . ARG C 3 98 ? -23.332 57.855 -28.338 1.00 19.13 ? 94 ARG H CA 1 ATOM 4881 C C . ARG C 3 98 ? -23.687 58.211 -26.897 1.00 20.97 ? 94 ARG H C 1 ATOM 4882 O O . ARG C 3 98 ? -24.867 58.367 -26.575 1.00 19.86 ? 94 ARG H O 1 ATOM 4883 C CB . ARG C 3 98 ? -23.505 59.084 -29.213 1.00 17.23 ? 94 ARG H CB 1 ATOM 4884 C CG . ARG C 3 98 ? -22.385 60.138 -28.939 1.00 17.49 ? 94 ARG H CG 1 ATOM 4885 C CD . ARG C 3 98 ? -22.549 61.276 -29.972 1.00 20.17 ? 94 ARG H CD 1 ATOM 4886 N NE . ARG C 3 98 ? -23.546 62.241 -29.504 1.00 22.72 ? 94 ARG H NE 1 ATOM 4887 C CZ . ARG C 3 98 ? -23.785 63.410 -30.100 1.00 25.97 ? 94 ARG H CZ 1 ATOM 4888 N NH1 . ARG C 3 98 ? -23.114 63.746 -31.205 1.00 24.38 ? 94 ARG H NH1 1 ATOM 4889 N NH2 . ARG C 3 98 ? -24.657 64.266 -29.570 1.00 27.31 ? 94 ARG H NH2 1 ATOM 4890 N N . HIS C 3 99 ? -22.660 58.296 -26.039 1.00 17.62 ? 95 HIS H N 1 ATOM 4891 C CA . HIS C 3 99 ? -22.774 58.692 -24.649 1.00 17.89 ? 95 HIS H CA 1 ATOM 4892 C C . HIS C 3 99 ? -22.958 60.234 -24.547 1.00 16.95 ? 95 HIS H C 1 ATOM 4893 O O . HIS C 3 99 ? -22.768 60.975 -25.528 1.00 20.56 ? 95 HIS H O 1 ATOM 4894 C CB . HIS C 3 99 ? -21.501 58.281 -23.949 1.00 18.89 ? 95 HIS H CB 1 ATOM 4895 C CG . HIS C 3 99 ? -21.352 56.792 -23.843 1.00 18.53 ? 95 HIS H CG 1 ATOM 4896 N ND1 . HIS C 3 99 ? -21.850 56.083 -22.776 1.00 18.89 ? 95 HIS H ND1 1 ATOM 4897 C CD2 . HIS C 3 99 ? -20.835 55.870 -24.711 1.00 18.52 ? 95 HIS H CD2 1 ATOM 4898 C CE1 . HIS C 3 99 ? -21.608 54.787 -22.954 1.00 19.51 ? 95 HIS H CE1 1 ATOM 4899 N NE2 . HIS C 3 99 ? -20.989 54.635 -24.112 1.00 19.00 ? 95 HIS H NE2 1 ATOM 4900 N N . GLY C 3 100 ? -23.369 60.672 -23.357 1.00 20.26 ? 96 GLY H N 1 ATOM 4901 C CA . GLY C 3 100 ? -23.631 62.088 -23.153 1.00 21.77 ? 96 GLY H CA 1 ATOM 4902 C C . GLY C 3 100 ? -22.320 62.894 -23.100 1.00 22.75 ? 96 GLY H C 1 ATOM 4903 O O . GLY C 3 100 ? -22.358 64.153 -23.184 1.00 24.29 ? 96 GLY H O 1 ATOM 4904 N N . ASN C 3 101 ? -21.187 62.221 -22.991 1.00 17.81 ? 97 ASN H N 1 ATOM 4905 C CA . ASN C 3 101 ? -19.888 62.917 -22.938 1.00 21.77 ? 97 ASN H CA 1 ATOM 4906 C C . ASN C 3 101 ? -18.804 62.019 -23.497 1.00 19.60 ? 97 ASN H C 1 ATOM 4907 O O . ASN C 3 101 ? -19.115 61.025 -24.202 1.00 18.49 ? 97 ASN H O 1 ATOM 4908 C CB . ASN C 3 101 ? -19.584 63.400 -21.500 1.00 18.20 ? 97 ASN H CB 1 ATOM 4909 C CG . ASN C 3 101 ? -19.113 62.290 -20.584 1.00 23.54 ? 97 ASN H CG 1 ATOM 4910 O OD1 . ASN C 3 101 ? -19.228 61.070 -20.873 1.00 21.44 ? 97 ASN H OD1 1 ATOM 4911 N ND2 . ASN C 3 101 ? -18.526 62.705 -19.446 1.00 24.94 ? 97 ASN H ND2 1 ATOM 4912 N N . TYR C 3 102 ? -17.538 62.344 -23.247 1.00 18.55 ? 98 TYR H N 1 ATOM 4913 C CA . TYR C 3 102 ? -16.414 61.632 -23.856 1.00 20.48 ? 98 TYR H CA 1 ATOM 4914 C C . TYR C 3 102 ? -16.127 60.225 -23.321 1.00 15.17 ? 98 TYR H C 1 ATOM 4915 O O . TYR C 3 102 ? -15.217 59.580 -23.806 1.00 16.66 ? 98 TYR H O 1 ATOM 4916 C CB . TYR C 3 102 ? -15.106 62.465 -23.668 1.00 19.26 ? 98 TYR H CB 1 ATOM 4917 C CG . TYR C 3 102 ? -14.617 62.461 -22.219 1.00 18.65 ? 98 TYR H CG 1 ATOM 4918 C CD1 . TYR C 3 102 ? -13.665 61.518 -21.784 1.00 18.49 ? 98 TYR H CD1 1 ATOM 4919 C CD2 . TYR C 3 102 ? -15.059 63.437 -21.321 1.00 21.12 ? 98 TYR H CD2 1 ATOM 4920 C CE1 . TYR C 3 102 ? -13.234 61.480 -20.424 1.00 19.44 ? 98 TYR H CE1 1 ATOM 4921 C CE2 . TYR C 3 102 ? -14.621 63.420 -19.966 1.00 19.72 ? 98 TYR H CE2 1 ATOM 4922 C CZ . TYR C 3 102 ? -13.728 62.477 -19.554 1.00 18.14 ? 98 TYR H CZ 1 ATOM 4923 O OH . TYR C 3 102 ? -13.319 62.500 -18.237 1.00 22.96 ? 98 TYR H OH 1 ATOM 4924 N N . TYR C 3 103 ? -16.887 59.742 -22.336 1.00 17.84 ? 99 TYR H N 1 ATOM 4925 C CA . TYR C 3 103 ? -16.532 58.466 -21.749 1.00 17.23 ? 99 TYR H CA 1 ATOM 4926 C C . TYR C 3 103 ? -17.811 57.615 -21.567 1.00 18.56 ? 99 TYR H C 1 ATOM 4927 O O . TYR C 3 103 ? -18.918 58.036 -21.930 1.00 17.98 ? 99 TYR H O 1 ATOM 4928 C CB . TYR C 3 103 ? -15.744 58.607 -20.414 1.00 17.63 ? 99 TYR H CB 1 ATOM 4929 C CG . TYR C 3 103 ? -14.763 57.518 -20.159 1.00 18.49 ? 99 TYR H CG 1 ATOM 4930 C CD1 . TYR C 3 103 ? -13.607 57.385 -20.929 1.00 19.41 ? 99 TYR H CD1 1 ATOM 4931 C CD2 . TYR C 3 103 ? -14.994 56.572 -19.113 1.00 18.77 ? 99 TYR H CD2 1 ATOM 4932 C CE1 . TYR C 3 103 ? -12.705 56.352 -20.661 1.00 21.58 ? 99 TYR H CE1 1 ATOM 4933 C CE2 . TYR C 3 103 ? -14.101 55.555 -18.875 1.00 19.84 ? 99 TYR H CE2 1 ATOM 4934 C CZ . TYR C 3 103 ? -12.984 55.440 -19.664 1.00 24.13 ? 99 TYR H CZ 1 ATOM 4935 O OH . TYR C 3 103 ? -12.046 54.453 -19.462 1.00 24.21 ? 99 TYR H OH 1 ATOM 4936 N N . TYR C 3 104 ? -17.619 56.415 -21.017 1.00 18.22 ? 100 TYR H N 1 ATOM 4937 C CA . TYR C 3 104 ? -18.648 55.334 -21.195 1.00 19.91 ? 100 TYR H CA 1 ATOM 4938 C C . TYR C 3 104 ? -19.621 55.270 -19.985 1.00 21.63 ? 100 TYR H C 1 ATOM 4939 O O . TYR C 3 104 ? -20.560 54.487 -19.989 1.00 21.21 ? 100 TYR H O 1 ATOM 4940 C CB . TYR C 3 104 ? -17.955 53.941 -21.349 1.00 20.11 ? 100 TYR H CB 1 ATOM 4941 C CG . TYR C 3 104 ? -16.822 53.993 -22.339 1.00 18.13 ? 100 TYR H CG 1 ATOM 4942 C CD1 . TYR C 3 104 ? -17.095 54.149 -23.690 1.00 17.83 ? 100 TYR H CD1 1 ATOM 4943 C CD2 . TYR C 3 104 ? -15.503 54.016 -21.927 1.00 17.51 ? 100 TYR H CD2 1 ATOM 4944 C CE1 . TYR C 3 104 ? -16.055 54.246 -24.606 1.00 18.76 ? 100 TYR H CE1 1 ATOM 4945 C CE2 . TYR C 3 104 ? -14.431 54.115 -22.848 1.00 20.56 ? 100 TYR H CE2 1 ATOM 4946 C CZ . TYR C 3 104 ? -14.740 54.248 -24.173 1.00 21.30 ? 100 TYR H CZ 1 ATOM 4947 O OH . TYR C 3 104 ? -13.735 54.378 -25.146 1.00 22.06 ? 100 TYR H OH 1 ATOM 4948 N N . TYR C 3 105 A -19.396 56.114 -18.971 1.00 19.55 ? 100 TYR H N 1 ATOM 4949 C CA . TYR C 3 105 A -20.277 56.072 -17.797 1.00 21.40 ? 100 TYR H CA 1 ATOM 4950 C C . TYR C 3 105 A -21.609 56.741 -18.067 1.00 25.46 ? 100 TYR H C 1 ATOM 4951 O O . TYR C 3 105 A -22.655 56.288 -17.527 1.00 25.98 ? 100 TYR H O 1 ATOM 4952 C CB . TYR C 3 105 A -19.611 56.821 -16.587 1.00 18.28 ? 100 TYR H CB 1 ATOM 4953 C CG . TYR C 3 105 A -18.192 56.412 -16.276 1.00 19.12 ? 100 TYR H CG 1 ATOM 4954 C CD1 . TYR C 3 105 A -17.753 55.092 -16.396 1.00 21.46 ? 100 TYR H CD1 1 ATOM 4955 C CD2 . TYR C 3 105 A -17.296 57.350 -15.814 1.00 25.13 ? 100 TYR H CD2 1 ATOM 4956 C CE1 . TYR C 3 105 A -16.427 54.726 -16.079 1.00 21.13 ? 100 TYR H CE1 1 ATOM 4957 C CE2 . TYR C 3 105 A -15.972 57.009 -15.485 1.00 23.02 ? 100 TYR H CE2 1 ATOM 4958 C CZ . TYR C 3 105 A -15.557 55.707 -15.609 1.00 24.45 ? 100 TYR H CZ 1 ATOM 4959 O OH . TYR C 3 105 A -14.285 55.360 -15.303 1.00 23.44 ? 100 TYR H OH 1 ATOM 4960 N N . SER C 3 106 B -21.588 57.821 -18.833 1.00 21.85 ? 100 SER H N 1 ATOM 4961 C CA . SER C 3 106 B -22.780 58.636 -19.068 1.00 19.67 ? 100 SER H CA 1 ATOM 4962 C C . SER C 3 106 B -23.873 57.882 -19.854 1.00 25.15 ? 100 SER H C 1 ATOM 4963 O O . SER C 3 106 B -23.562 56.922 -20.587 1.00 23.32 ? 100 SER H O 1 ATOM 4964 C CB . SER C 3 106 B -22.440 59.968 -19.799 1.00 22.81 ? 100 SER H CB 1 ATOM 4965 O OG . SER C 3 106 B -21.732 59.666 -20.979 1.00 23.03 ? 100 SER H OG 1 ATOM 4966 N N . GLY C 3 107 C -25.139 58.227 -19.642 1.00 20.69 ? 100 GLY H N 1 ATOM 4967 C CA . GLY C 3 107 C -26.238 57.577 -20.400 1.00 21.53 ? 100 GLY H CA 1 ATOM 4968 C C . GLY C 3 107 C -26.010 57.687 -21.931 1.00 25.08 ? 100 GLY H C 1 ATOM 4969 O O . GLY C 3 107 C -25.516 58.698 -22.479 1.00 23.21 ? 100 GLY H O 1 ATOM 4970 N N . MET C 3 108 D -26.397 56.624 -22.657 1.00 19.17 ? 100 MET H N 1 ATOM 4971 C CA . MET C 3 108 D -26.274 56.652 -24.070 1.00 16.70 ? 100 MET H CA 1 ATOM 4972 C C . MET C 3 108 D -27.544 57.290 -24.663 1.00 22.79 ? 100 MET H C 1 ATOM 4973 O O . MET C 3 108 D -28.629 56.686 -24.630 1.00 19.68 ? 100 MET H O 1 ATOM 4974 C CB . MET C 3 108 D -26.111 55.216 -24.619 1.00 19.45 ? 100 MET H CB 1 ATOM 4975 C CG . MET C 3 108 D -24.878 54.583 -24.057 1.00 21.35 ? 100 MET H CG 1 ATOM 4976 S SD . MET C 3 108 D -24.788 52.828 -24.574 1.00 28.23 ? 100 MET H SD 1 ATOM 4977 C CE . MET C 3 108 D -25.847 52.136 -23.473 1.00 32.78 ? 100 MET H CE 1 ATOM 4978 N N . ASP C 3 109 ? -27.425 58.498 -25.199 1.00 20.66 ? 101 ASP H N 1 ATOM 4979 C CA . ASP C 3 109 ? -28.636 59.184 -25.621 1.00 22.79 ? 101 ASP H CA 1 ATOM 4980 C C . ASP C 3 109 ? -28.926 59.266 -27.096 1.00 21.15 ? 101 ASP H C 1 ATOM 4981 O O . ASP C 3 109 ? -30.049 59.671 -27.469 1.00 26.11 ? 101 ASP H O 1 ATOM 4982 C CB . ASP C 3 109 ? -28.763 60.602 -24.995 1.00 29.29 ? 101 ASP H CB 1 ATOM 4983 C CG . ASP C 3 109 ? -27.711 61.540 -25.506 1.00 37.80 ? 101 ASP H CG 1 ATOM 4984 O OD1 . ASP C 3 109 ? -26.663 61.063 -25.981 1.00 28.15 ? 101 ASP H OD1 1 ATOM 4985 O OD2 . ASP C 3 109 ? -27.902 62.768 -25.428 1.00 41.50 ? 101 ASP H OD2 1 ATOM 4986 N N . VAL C 3 110 ? -27.981 58.930 -27.980 1.00 20.48 ? 102 VAL H N 1 ATOM 4987 C CA . VAL C 3 110 ? -28.268 58.973 -29.393 1.00 18.87 ? 102 VAL H CA 1 ATOM 4988 C C . VAL C 3 110 ? -27.943 57.567 -29.891 1.00 22.39 ? 102 VAL H C 1 ATOM 4989 O O . VAL C 3 110 ? -26.861 57.101 -29.626 1.00 21.04 ? 102 VAL H O 1 ATOM 4990 C CB . VAL C 3 110 ? -27.361 59.927 -30.148 1.00 21.36 ? 102 VAL H CB 1 ATOM 4991 C CG1 . VAL C 3 110 ? -27.774 60.001 -31.613 1.00 22.86 ? 102 VAL H CG1 1 ATOM 4992 C CG2 . VAL C 3 110 ? -27.424 61.351 -29.491 1.00 23.48 ? 102 VAL H CG2 1 ATOM 4993 N N . TRP C 3 111 ? -28.883 56.917 -30.579 1.00 19.98 ? 103 TRP H N 1 ATOM 4994 C CA . TRP C 3 111 ? -28.627 55.525 -31.008 1.00 21.01 ? 103 TRP H CA 1 ATOM 4995 C C . TRP C 3 111 ? -28.738 55.399 -32.511 1.00 18.06 ? 103 TRP H C 1 ATOM 4996 O O . TRP C 3 111 ? -29.620 56.007 -33.172 1.00 21.10 ? 103 TRP H O 1 ATOM 4997 C CB . TRP C 3 111 ? -29.691 54.579 -30.343 1.00 18.16 ? 103 TRP H CB 1 ATOM 4998 C CG . TRP C 3 111 ? -29.483 54.343 -28.865 1.00 19.46 ? 103 TRP H CG 1 ATOM 4999 C CD1 . TRP C 3 111 ? -29.654 55.274 -27.848 1.00 20.89 ? 103 TRP H CD1 1 ATOM 5000 C CD2 . TRP C 3 111 ? -29.053 53.152 -28.250 1.00 17.16 ? 103 TRP H CD2 1 ATOM 5001 N NE1 . TRP C 3 111 ? -29.391 54.708 -26.652 1.00 20.29 ? 103 TRP H NE1 1 ATOM 5002 C CE2 . TRP C 3 111 ? -28.995 53.395 -26.847 1.00 18.97 ? 103 TRP H CE2 1 ATOM 5003 C CE3 . TRP C 3 111 ? -28.701 51.853 -28.736 1.00 14.90 ? 103 TRP H CE3 1 ATOM 5004 C CZ2 . TRP C 3 111 ? -28.584 52.441 -25.924 1.00 19.92 ? 103 TRP H CZ2 1 ATOM 5005 C CZ3 . TRP C 3 111 ? -28.281 50.896 -27.779 1.00 18.03 ? 103 TRP H CZ3 1 ATOM 5006 C CH2 . TRP C 3 111 ? -28.254 51.175 -26.392 1.00 18.48 ? 103 TRP H CH2 1 ATOM 5007 N N . GLY C 3 112 ? -27.929 54.513 -33.073 1.00 19.11 ? 104 GLY H N 1 ATOM 5008 C CA . GLY C 3 112 ? -28.093 54.146 -34.455 1.00 18.08 ? 104 GLY H CA 1 ATOM 5009 C C . GLY C 3 112 ? -29.322 53.218 -34.623 1.00 17.80 ? 104 GLY H C 1 ATOM 5010 O O . GLY C 3 112 ? -29.954 52.795 -33.649 1.00 21.44 ? 104 GLY H O 1 ATOM 5011 N N . GLN C 3 113 ? -29.626 52.901 -35.882 1.00 18.68 ? 105 GLN H N 1 ATOM 5012 C CA . GLN C 3 113 ? -30.853 52.146 -36.160 1.00 21.62 ? 105 GLN H CA 1 ATOM 5013 C C . GLN C 3 113 ? -30.710 50.641 -35.938 1.00 24.87 ? 105 GLN H C 1 ATOM 5014 O O . GLN C 3 113 ? -31.726 49.905 -35.942 1.00 22.04 ? 105 GLN H O 1 ATOM 5015 C CB . GLN C 3 113 ? -31.439 52.471 -37.548 1.00 20.44 ? 105 GLN H CB 1 ATOM 5016 C CG . GLN C 3 113 ? -30.843 51.706 -38.731 1.00 19.49 ? 105 GLN H CG 1 ATOM 5017 C CD . GLN C 3 113 ? -29.509 52.267 -39.254 1.00 22.60 ? 105 GLN H CD 1 ATOM 5018 O OE1 . GLN C 3 113 ? -28.788 53.022 -38.566 1.00 23.24 ? 105 GLN H OE1 1 ATOM 5019 N NE2 . GLN C 3 113 ? -29.182 51.896 -40.500 1.00 21.32 ? 105 GLN H NE2 1 ATOM 5020 N N . GLY C 3 114 ? -29.467 50.189 -35.797 1.00 19.81 ? 106 GLY H N 1 ATOM 5021 C CA . GLY C 3 114 ? -29.166 48.790 -35.613 1.00 20.07 ? 106 GLY H CA 1 ATOM 5022 C C . GLY C 3 114 ? -28.821 48.143 -36.937 1.00 19.39 ? 106 GLY H C 1 ATOM 5023 O O . GLY C 3 114 ? -29.229 48.622 -38.016 1.00 21.02 ? 106 GLY H O 1 ATOM 5024 N N . THR C 3 115 ? -27.995 47.097 -36.832 1.00 17.61 ? 107 THR H N 1 ATOM 5025 C CA . THR C 3 115 ? -27.586 46.285 -37.983 1.00 16.81 ? 107 THR H CA 1 ATOM 5026 C C . THR C 3 115 ? -27.743 44.842 -37.614 1.00 18.53 ? 107 THR H C 1 ATOM 5027 O O . THR C 3 115 ? -27.165 44.372 -36.611 1.00 19.31 ? 107 THR H O 1 ATOM 5028 C CB . THR C 3 115 ? -26.094 46.537 -38.277 1.00 21.87 ? 107 THR H CB 1 ATOM 5029 O OG1 . THR C 3 115 ? -25.894 47.891 -38.659 1.00 20.36 ? 107 THR H OG1 1 ATOM 5030 C CG2 . THR C 3 115 ? -25.600 45.650 -39.488 1.00 20.28 ? 107 THR H CG2 1 ATOM 5031 N N . THR C 3 116 ? -28.551 44.124 -38.430 1.00 21.02 ? 108 THR H N 1 ATOM 5032 C CA . THR C 3 116 ? -28.783 42.706 -38.167 1.00 16.94 ? 108 THR H CA 1 ATOM 5033 C C . THR C 3 116 ? -27.633 41.920 -38.768 1.00 20.64 ? 108 THR H C 1 ATOM 5034 O O . THR C 3 116 ? -27.237 42.176 -39.916 1.00 24.07 ? 108 THR H O 1 ATOM 5035 C CB . THR C 3 116 ? -30.096 42.278 -38.875 1.00 22.81 ? 108 THR H CB 1 ATOM 5036 O OG1 . THR C 3 116 ? -31.203 43.003 -38.295 1.00 25.79 ? 108 THR H OG1 1 ATOM 5037 C CG2 . THR C 3 116 ? -30.306 40.805 -38.629 1.00 32.02 ? 108 THR H CG2 1 ATOM 5038 N N . VAL C 3 117 ? -27.051 41.015 -37.981 1.00 18.16 ? 109 VAL H N 1 ATOM 5039 C CA . VAL C 3 117 ? -26.035 40.091 -38.514 1.00 17.51 ? 109 VAL H CA 1 ATOM 5040 C C . VAL C 3 117 ? -26.584 38.685 -38.303 1.00 20.44 ? 109 VAL H C 1 ATOM 5041 O O . VAL C 3 117 ? -26.971 38.320 -37.191 1.00 18.80 ? 109 VAL H O 1 ATOM 5042 C CB . VAL C 3 117 ? -24.735 40.244 -37.753 1.00 20.54 ? 109 VAL H CB 1 ATOM 5043 C CG1 . VAL C 3 117 ? -23.724 39.228 -38.266 1.00 22.35 ? 109 VAL H CG1 1 ATOM 5044 C CG2 . VAL C 3 117 ? -24.202 41.683 -37.979 1.00 21.22 ? 109 VAL H CG2 1 ATOM 5045 N N . THR C 3 118 ? -26.641 37.897 -39.388 1.00 20.34 ? 110 THR H N 1 ATOM 5046 C CA . THR C 3 118 ? -27.183 36.533 -39.308 1.00 22.02 ? 110 THR H CA 1 ATOM 5047 C C . THR C 3 118 ? -26.080 35.582 -39.709 1.00 20.75 ? 110 THR H C 1 ATOM 5048 O O . THR C 3 118 ? -25.459 35.783 -40.770 1.00 22.37 ? 110 THR H O 1 ATOM 5049 C CB . THR C 3 118 ? -28.322 36.391 -40.313 1.00 22.02 ? 110 THR H CB 1 ATOM 5050 O OG1 . THR C 3 118 ? -29.331 37.356 -39.984 1.00 25.55 ? 110 THR H OG1 1 ATOM 5051 C CG2 . THR C 3 118 ? -28.911 34.977 -40.220 1.00 25.16 ? 110 THR H CG2 1 ATOM 5052 N N . VAL C 3 119 ? -25.744 34.651 -38.825 1.00 20.83 ? 111 VAL H N 1 ATOM 5053 C CA . VAL C 3 119 ? -24.604 33.751 -39.066 1.00 21.94 ? 111 VAL H CA 1 ATOM 5054 C C . VAL C 3 119 ? -25.192 32.345 -39.353 1.00 26.09 ? 111 VAL H C 1 ATOM 5055 O O . VAL C 3 119 ? -25.924 31.802 -38.528 1.00 24.20 ? 111 VAL H O 1 ATOM 5056 C CB . VAL C 3 119 ? -23.687 33.693 -37.847 1.00 21.35 ? 111 VAL H CB 1 ATOM 5057 C CG1 . VAL C 3 119 ? -22.476 32.762 -38.087 1.00 24.63 ? 111 VAL H CG1 1 ATOM 5058 C CG2 . VAL C 3 119 ? -23.147 35.103 -37.516 1.00 22.02 ? 111 VAL H CG2 1 ATOM 5059 N N . SER C 3 120 ? -24.841 31.765 -40.504 1.00 21.54 ? 112 SER H N 1 ATOM 5060 C CA . SER C 3 120 ? -25.473 30.483 -40.898 1.00 21.22 ? 112 SER H CA 1 ATOM 5061 C C . SER C 3 120 ? -24.543 29.796 -41.908 1.00 26.72 ? 112 SER H C 1 ATOM 5062 O O . SER C 3 120 ? -23.857 30.466 -42.704 1.00 25.66 ? 112 SER H O 1 ATOM 5063 C CB . SER C 3 120 ? -26.788 30.743 -41.598 1.00 28.30 ? 112 SER H CB 1 ATOM 5064 O OG . SER C 3 120 ? -27.303 29.520 -42.142 1.00 28.85 ? 112 SER H OG 1 ATOM 5065 N N . SER C 3 121 ? -24.525 28.462 -41.885 1.00 25.89 ? 113 SER H N 1 ATOM 5066 C CA . SER C 3 121 ? -23.740 27.735 -42.893 1.00 24.32 ? 113 SER H CA 1 ATOM 5067 C C . SER C 3 121 ? -24.564 27.410 -44.146 1.00 31.44 ? 113 SER H C 1 ATOM 5068 O O . SER C 3 121 ? -24.085 26.734 -45.077 1.00 26.81 ? 113 SER H O 1 ATOM 5069 C CB . SER C 3 121 ? -23.222 26.415 -42.259 1.00 25.44 ? 113 SER H CB 1 ATOM 5070 O OG . SER C 3 121 ? -24.334 25.620 -41.930 1.00 27.85 ? 113 SER H OG 1 ATOM 5071 N N . ALA C 3 122 ? -25.789 27.919 -44.208 1.00 28.09 ? 114 ALA H N 1 ATOM 5072 C CA . ALA C 3 122 ? -26.605 27.691 -45.387 1.00 28.59 ? 114 ALA H CA 1 ATOM 5073 C C . ALA C 3 122 ? -26.050 28.406 -46.620 1.00 33.73 ? 114 ALA H C 1 ATOM 5074 O O . ALA C 3 122 ? -25.417 29.464 -46.510 1.00 28.56 ? 114 ALA H O 1 ATOM 5075 C CB . ALA C 3 122 ? -28.039 28.095 -45.134 1.00 28.58 ? 114 ALA H CB 1 ATOM 5076 N N . SER C 3 123 ? -26.281 27.810 -47.790 1.00 30.42 ? 115 SER H N 1 ATOM 5077 C CA . SER C 3 123 ? -25.879 28.395 -49.039 1.00 30.89 ? 115 SER H CA 1 ATOM 5078 C C . SER C 3 123 ? -27.036 29.147 -49.652 1.00 29.68 ? 115 SER H C 1 ATOM 5079 O O . SER C 3 123 ? -28.179 28.686 -49.629 1.00 34.43 ? 115 SER H O 1 ATOM 5080 C CB . SER C 3 123 ? -25.410 27.312 -50.071 1.00 32.17 ? 115 SER H CB 1 ATOM 5081 O OG . SER C 3 123 ? -24.235 26.633 -49.607 1.00 38.78 ? 115 SER H OG 1 ATOM 5082 N N . THR C 3 124 ? -26.720 30.283 -50.254 1.00 30.80 ? 116 THR H N 1 ATOM 5083 C CA . THR C 3 124 ? -27.694 31.023 -51.068 1.00 32.67 ? 116 THR H CA 1 ATOM 5084 C C . THR C 3 124 ? -28.501 30.121 -52.030 1.00 36.70 ? 116 THR H C 1 ATOM 5085 O O . THR C 3 124 ? -27.941 29.289 -52.772 1.00 32.95 ? 116 THR H O 1 ATOM 5086 C CB . THR C 3 124 ? -27.010 32.079 -51.926 1.00 31.02 ? 116 THR H CB 1 ATOM 5087 O OG1 . THR C 3 124 ? -26.184 32.904 -51.108 1.00 34.43 ? 116 THR H OG1 1 ATOM 5088 C CG2 . THR C 3 124 ? -28.058 32.958 -52.664 1.00 40.01 ? 116 THR H CG2 1 ATOM 5089 N N . LYS C 3 125 ? -29.816 30.272 -51.989 1.00 35.18 ? 117 LYS H N 1 ATOM 5090 C CA . LYS C 3 125 ? -30.702 29.404 -52.747 1.00 34.12 ? 117 LYS H CA 1 ATOM 5091 C C . LYS C 3 125 ? -32.004 30.161 -52.973 1.00 38.06 ? 117 LYS H C 1 ATOM 5092 O O . LYS C 3 125 ? -32.614 30.678 -52.011 1.00 33.09 ? 117 LYS H O 1 ATOM 5093 C CB . LYS C 3 125 ? -30.988 28.123 -51.975 1.00 35.85 ? 117 LYS H CB 1 ATOM 5094 C CG . LYS C 3 125 ? -31.935 27.152 -52.779 1.00 40.42 ? 117 LYS H CG 1 ATOM 5095 C CD . LYS C 3 125 ? -32.312 25.908 -52.016 1.00 36.47 ? 117 LYS H CD 1 ATOM 5096 C CE . LYS C 3 125 ? -33.351 25.102 -52.807 1.00 49.37 ? 117 LYS H CE 1 ATOM 5097 N NZ . LYS C 3 125 ? -34.588 25.953 -53.062 1.00 49.19 ? 117 LYS H NZ 1 ATOM 5098 N N . GLY C 3 126 ? -32.419 30.255 -54.233 1.00 34.89 ? 118 GLY H N 1 ATOM 5099 C CA . GLY C 3 126 ? -33.679 30.915 -54.561 1.00 31.81 ? 118 GLY H CA 1 ATOM 5100 C C . GLY C 3 126 ? -34.841 30.002 -54.253 1.00 37.33 ? 118 GLY H C 1 ATOM 5101 O O . GLY C 3 126 ? -34.695 28.781 -54.224 1.00 39.28 ? 118 GLY H O 1 ATOM 5102 N N . PRO C 3 127 ? -36.022 30.595 -54.043 1.00 36.39 ? 119 PRO H N 1 ATOM 5103 C CA . PRO C 3 127 ? -37.224 29.870 -53.609 1.00 33.01 ? 119 PRO H CA 1 ATOM 5104 C C . PRO C 3 127 ? -37.881 29.089 -54.758 1.00 42.79 ? 119 PRO H C 1 ATOM 5105 O O . PRO C 3 127 ? -37.781 29.479 -55.919 1.00 39.34 ? 119 PRO H O 1 ATOM 5106 C CB . PRO C 3 127 ? -38.184 31.004 -53.208 1.00 29.99 ? 119 PRO H CB 1 ATOM 5107 C CG . PRO C 3 127 ? -37.790 32.159 -54.112 1.00 38.70 ? 119 PRO H CG 1 ATOM 5108 C CD . PRO C 3 127 ? -36.267 32.033 -54.277 1.00 32.07 ? 119 PRO H CD 1 ATOM 5109 N N . SER C 3 128 ? -38.545 27.995 -54.405 1.00 34.76 ? 120 SER H N 1 ATOM 5110 C CA . SER C 3 128 ? -39.545 27.357 -55.272 1.00 46.16 ? 120 SER H CA 1 ATOM 5111 C C . SER C 3 128 ? -40.916 27.865 -54.821 1.00 57.01 ? 120 SER H C 1 ATOM 5112 O O . SER C 3 128 ? -41.263 27.740 -53.637 1.00 45.27 ? 120 SER H O 1 ATOM 5113 C CB . SER C 3 128 ? -39.499 25.844 -55.095 1.00 48.55 ? 120 SER H CB 1 ATOM 5114 O OG . SER C 3 128 ? -38.247 25.320 -55.510 1.00 49.92 ? 120 SER H OG 1 ATOM 5115 N N . VAL C 3 129 ? -41.695 28.426 -55.751 1.00 50.17 ? 121 VAL H N 1 ATOM 5116 C CA . VAL C 3 129 ? -42.984 29.063 -55.412 1.00 45.79 ? 121 VAL H CA 1 ATOM 5117 C C . VAL C 3 129 ? -44.193 28.266 -55.917 1.00 60.78 ? 121 VAL H C 1 ATOM 5118 O O . VAL C 3 129 ? -44.286 27.923 -57.105 1.00 48.80 ? 121 VAL H O 1 ATOM 5119 C CB . VAL C 3 129 ? -43.031 30.486 -55.994 1.00 41.61 ? 121 VAL H CB 1 ATOM 5120 C CG1 . VAL C 3 129 ? -42.441 30.444 -57.348 1.00 64.63 ? 121 VAL H CG1 1 ATOM 5121 C CG2 . VAL C 3 129 ? -44.489 31.036 -56.060 1.00 45.43 ? 121 VAL H CG2 1 ATOM 5122 N N . PHE C 3 130 ? -45.116 27.971 -55.009 1.00 50.75 ? 122 PHE H N 1 ATOM 5123 C CA . PHE C 3 130 ? -46.320 27.226 -55.351 1.00 45.27 ? 122 PHE H CA 1 ATOM 5124 C C . PHE C 3 130 ? -47.598 28.026 -55.124 1.00 53.73 ? 122 PHE H C 1 ATOM 5125 O O . PHE C 3 130 ? -47.655 28.904 -54.246 1.00 49.83 ? 122 PHE H O 1 ATOM 5126 C CB . PHE C 3 130 ? -46.336 25.920 -54.565 1.00 41.97 ? 122 PHE H CB 1 ATOM 5127 C CG . PHE C 3 130 ? -45.189 25.023 -54.922 1.00 57.90 ? 122 PHE H CG 1 ATOM 5128 C CD1 . PHE C 3 130 ? -45.128 24.437 -56.187 1.00 53.01 ? 122 PHE H CD1 1 ATOM 5129 C CD2 . PHE C 3 130 ? -44.160 24.782 -54.021 1.00 54.11 ? 122 PHE H CD2 1 ATOM 5130 C CE1 . PHE C 3 130 ? -44.064 23.608 -56.544 1.00 69.59 ? 122 PHE H CE1 1 ATOM 5131 C CE2 . PHE C 3 130 ? -43.088 23.954 -54.365 1.00 55.02 ? 122 PHE H CE2 1 ATOM 5132 C CZ . PHE C 3 130 ? -43.038 23.368 -55.633 1.00 64.33 ? 122 PHE H CZ 1 ATOM 5133 N N . PRO C 3 131 ? -48.637 27.744 -55.930 1.00 56.22 ? 123 PRO H N 1 ATOM 5134 C CA . PRO C 3 131 ? -49.885 28.485 -55.729 1.00 57.09 ? 123 PRO H CA 1 ATOM 5135 C C . PRO C 3 131 ? -50.722 27.856 -54.611 1.00 54.81 ? 123 PRO H C 1 ATOM 5136 O O . PRO C 3 131 ? -50.659 26.637 -54.358 1.00 49.03 ? 123 PRO H O 1 ATOM 5137 C CB . PRO C 3 131 ? -50.579 28.380 -57.098 1.00 56.89 ? 123 PRO H CB 1 ATOM 5138 C CG . PRO C 3 131 ? -50.133 27.044 -57.622 1.00 57.76 ? 123 PRO H CG 1 ATOM 5139 C CD . PRO C 3 131 ? -48.724 26.807 -57.069 1.00 61.12 ? 123 PRO H CD 1 ATOM 5140 N N . LEU C 3 132 ? -51.463 28.718 -53.918 1.00 51.24 ? 124 LEU H N 1 ATOM 5141 C CA . LEU C 3 132 ? -52.378 28.313 -52.860 1.00 55.76 ? 124 LEU H CA 1 ATOM 5142 C C . LEU C 3 132 ? -53.760 28.686 -53.374 1.00 54.64 ? 124 LEU H C 1 ATOM 5143 O O . LEU C 3 132 ? -54.135 29.863 -53.347 1.00 60.09 ? 124 LEU H O 1 ATOM 5144 C CB . LEU C 3 132 ? -52.066 29.082 -51.573 1.00 53.40 ? 124 LEU H CB 1 ATOM 5145 C CG . LEU C 3 132 ? -50.659 28.799 -51.058 1.00 56.93 ? 124 LEU H CG 1 ATOM 5146 C CD1 . LEU C 3 132 ? -50.337 29.627 -49.828 1.00 52.63 ? 124 LEU H CD1 1 ATOM 5147 C CD2 . LEU C 3 132 ? -50.537 27.300 -50.772 1.00 59.50 ? 124 LEU H CD2 1 ATOM 5148 N N . ALA C 3 133 ? -54.499 27.694 -53.878 1.00 61.04 ? 125 ALA H N 1 ATOM 5149 C CA . ALA C 3 133 ? -55.787 27.942 -54.550 1.00 66.02 ? 125 ALA H CA 1 ATOM 5150 C C . ALA C 3 133 ? -56.977 28.141 -53.597 1.00 61.70 ? 125 ALA H C 1 ATOM 5151 O O . ALA C 3 133 ? -57.079 27.459 -52.572 1.00 70.87 ? 125 ALA H O 1 ATOM 5152 C CB . ALA C 3 133 ? -56.090 26.816 -55.547 1.00 62.39 ? 125 ALA H CB 1 ATOM 5153 N N . PRO C 3 134 ? -57.895 29.062 -53.951 1.00 73.82 ? 126 PRO H N 1 ATOM 5154 C CA . PRO C 3 134 ? -59.108 29.311 -53.150 1.00 71.54 ? 126 PRO H CA 1 ATOM 5155 C C . PRO C 3 134 ? -59.985 28.061 -53.023 1.00 61.90 ? 126 PRO H C 1 ATOM 5156 O O . PRO C 3 134 ? -60.249 27.590 -51.917 1.00 71.03 ? 126 PRO H O 1 ATOM 5157 C CB . PRO C 3 134 ? -59.860 30.370 -53.963 1.00 73.19 ? 126 PRO H CB 1 ATOM 5158 C CG . PRO C 3 134 ? -58.868 30.946 -54.926 1.00 66.12 ? 126 PRO H CG 1 ATOM 5159 C CD . PRO C 3 134 ? -57.841 29.891 -55.173 1.00 73.23 ? 126 PRO H CD 1 ATOM 5160 N N . GLY C 3 141 ? -70.397 33.396 -50.903 1.00 94.01 ? 133 GLY H N 1 ATOM 5161 C CA . GLY C 3 141 ? -69.179 33.437 -50.111 1.00 95.86 ? 133 GLY H CA 1 ATOM 5162 C C . GLY C 3 141 ? -68.804 34.824 -49.608 1.00 105.60 ? 133 GLY H C 1 ATOM 5163 O O . GLY C 3 141 ? -68.439 35.002 -48.438 1.00 103.19 ? 133 GLY H O 1 ATOM 5164 N N . GLY C 3 142 ? -68.899 35.815 -50.493 1.00 101.02 ? 134 GLY H N 1 ATOM 5165 C CA . GLY C 3 142 ? -68.505 37.174 -50.164 1.00 97.35 ? 134 GLY H CA 1 ATOM 5166 C C . GLY C 3 142 ? -67.043 37.429 -50.490 1.00 96.16 ? 134 GLY H C 1 ATOM 5167 O O . GLY C 3 142 ? -66.727 38.174 -51.419 1.00 97.50 ? 134 GLY H O 1 ATOM 5168 N N . THR C 3 143 ? -66.148 36.802 -49.729 1.00 91.13 ? 135 THR H N 1 ATOM 5169 C CA . THR C 3 143 ? -64.711 36.995 -49.917 1.00 87.18 ? 135 THR H CA 1 ATOM 5170 C C . THR C 3 143 ? -63.970 35.667 -49.923 1.00 87.19 ? 135 THR H C 1 ATOM 5171 O O . THR C 3 143 ? -64.411 34.701 -49.294 1.00 86.62 ? 135 THR H O 1 ATOM 5172 C CB . THR C 3 143 ? -64.106 37.846 -48.793 1.00 84.62 ? 135 THR H CB 1 ATOM 5173 O OG1 . THR C 3 143 ? -64.471 37.274 -47.529 1.00 91.25 ? 135 THR H OG1 1 ATOM 5174 C CG2 . THR C 3 143 ? -64.605 39.293 -48.875 1.00 80.27 ? 135 THR H CG2 1 ATOM 5175 N N . ALA C 3 144 ? -62.834 35.633 -50.620 1.00 83.58 ? 136 ALA H N 1 ATOM 5176 C CA . ALA C 3 144 ? -62.006 34.427 -50.711 1.00 79.18 ? 136 ALA H CA 1 ATOM 5177 C C . ALA C 3 144 ? -60.542 34.682 -50.331 1.00 76.10 ? 136 ALA H C 1 ATOM 5178 O O . ALA C 3 144 ? -60.073 35.831 -50.340 1.00 73.49 ? 136 ALA H O 1 ATOM 5179 C CB . ALA C 3 144 ? -62.091 33.824 -52.114 1.00 73.24 ? 136 ALA H CB 1 ATOM 5180 N N . ALA C 3 145 ? -59.836 33.597 -49.999 1.00 65.03 ? 137 ALA H N 1 ATOM 5181 C CA . ALA C 3 145 ? -58.406 33.647 -49.654 1.00 72.59 ? 137 ALA H CA 1 ATOM 5182 C C . ALA C 3 145 ? -57.560 32.787 -50.593 1.00 68.47 ? 137 ALA H C 1 ATOM 5183 O O . ALA C 3 145 ? -57.724 31.560 -50.675 1.00 60.87 ? 137 ALA H O 1 ATOM 5184 C CB . ALA C 3 145 ? -58.178 33.215 -48.221 1.00 56.52 ? 137 ALA H CB 1 ATOM 5185 N N . LEU C 3 146 ? -56.647 33.439 -51.300 1.00 64.17 ? 138 LEU H N 1 ATOM 5186 C CA . LEU C 3 146 ? -55.724 32.723 -52.165 1.00 62.71 ? 138 LEU H CA 1 ATOM 5187 C C . LEU C 3 146 ? -54.303 33.277 -51.957 1.00 64.31 ? 138 LEU H C 1 ATOM 5188 O O . LEU C 3 146 ? -54.126 34.447 -51.591 1.00 58.08 ? 138 LEU H O 1 ATOM 5189 C CB . LEU C 3 146 ? -56.179 32.819 -53.632 1.00 55.05 ? 138 LEU H CB 1 ATOM 5190 C CG . LEU C 3 146 ? -56.434 34.226 -54.200 1.00 67.87 ? 138 LEU H CG 1 ATOM 5191 C CD1 . LEU C 3 146 ? -55.150 34.828 -54.736 1.00 66.90 ? 138 LEU H CD1 1 ATOM 5192 C CD2 . LEU C 3 146 ? -57.509 34.227 -55.294 1.00 66.20 ? 138 LEU H CD2 1 ATOM 5193 N N . GLY C 3 147 ? -53.291 32.448 -52.184 1.00 64.07 ? 139 GLY H N 1 ATOM 5194 C CA . GLY C 3 147 ? -51.932 32.903 -51.967 1.00 62.14 ? 139 GLY H CA 1 ATOM 5195 C C . GLY C 3 147 ? -50.832 32.178 -52.714 1.00 60.51 ? 139 GLY H C 1 ATOM 5196 O O . GLY C 3 147 ? -51.076 31.424 -53.659 1.00 53.62 ? 139 GLY H O 1 ATOM 5197 N N . CYS C 3 148 ? -49.600 32.432 -52.280 1.00 52.86 ? 140 CYS H N 1 ATOM 5198 C CA . CYS C 3 148 ? -48.432 31.747 -52.821 1.00 53.25 ? 140 CYS H CA 1 ATOM 5199 C C . CYS C 3 148 ? -47.596 31.232 -51.686 1.00 51.89 ? 140 CYS H C 1 ATOM 5200 O O . CYS C 3 148 ? -47.457 31.898 -50.655 1.00 49.50 ? 140 CYS H O 1 ATOM 5201 C CB . CYS C 3 148 ? -47.606 32.701 -53.667 1.00 56.68 ? 140 CYS H CB 1 ATOM 5202 S SG . CYS C 3 148 ? -48.304 32.858 -55.306 1.00 64.36 ? 140 CYS H SG 1 ATOM 5203 N N . LEU C 3 149 ? -47.054 30.036 -51.857 1.00 44.90 ? 141 LEU H N 1 ATOM 5204 C CA . LEU C 3 149 ? -46.149 29.471 -50.877 1.00 46.42 ? 141 LEU H CA 1 ATOM 5205 C C . LEU C 3 149 ? -44.742 29.674 -51.415 1.00 50.70 ? 141 LEU H C 1 ATOM 5206 O O . LEU C 3 149 ? -44.446 29.277 -52.554 1.00 40.94 ? 141 LEU H O 1 ATOM 5207 C CB . LEU C 3 149 ? -46.436 27.996 -50.695 1.00 47.62 ? 141 LEU H CB 1 ATOM 5208 C CG . LEU C 3 149 ? -45.333 27.179 -50.044 1.00 51.42 ? 141 LEU H CG 1 ATOM 5209 C CD1 . LEU C 3 149 ? -45.126 27.646 -48.596 1.00 47.03 ? 141 LEU H CD1 1 ATOM 5210 C CD2 . LEU C 3 149 ? -45.702 25.717 -50.090 1.00 45.28 ? 141 LEU H CD2 1 ATOM 5211 N N . VAL C 3 150 ? -43.879 30.314 -50.623 1.00 40.27 ? 142 VAL H N 1 ATOM 5212 C CA . VAL C 3 150 ? -42.526 30.598 -51.099 1.00 40.20 ? 142 VAL H CA 1 ATOM 5213 C C . VAL C 3 150 ? -41.552 29.749 -50.327 1.00 41.72 ? 142 VAL H C 1 ATOM 5214 O O . VAL C 3 150 ? -41.250 30.035 -49.162 1.00 38.24 ? 142 VAL H O 1 ATOM 5215 C CB . VAL C 3 150 ? -42.228 32.090 -51.023 1.00 46.63 ? 142 VAL H CB 1 ATOM 5216 C CG1 . VAL C 3 150 ? -40.831 32.402 -51.507 1.00 42.52 ? 142 VAL H CG1 1 ATOM 5217 C CG2 . VAL C 3 150 ? -43.242 32.823 -51.878 1.00 47.08 ? 142 VAL H CG2 1 ATOM 5218 N N . LYS C 3 151 ? -41.063 28.692 -50.982 1.00 38.42 ? 143 LYS H N 1 ATOM 5219 C CA . LYS C 3 151 ? -40.377 27.586 -50.323 1.00 38.68 ? 143 LYS H CA 1 ATOM 5220 C C . LYS C 3 151 ? -38.846 27.508 -50.448 1.00 39.66 ? 143 LYS H C 1 ATOM 5221 O O . LYS C 3 151 ? -38.275 27.713 -51.533 1.00 39.26 ? 143 LYS H O 1 ATOM 5222 C CB . LYS C 3 151 ? -40.919 26.260 -50.862 1.00 44.17 ? 143 LYS H CB 1 ATOM 5223 C CG . LYS C 3 151 ? -42.040 25.655 -50.104 1.00 49.28 ? 143 LYS H CG 1 ATOM 5224 C CD . LYS C 3 151 ? -42.379 24.268 -50.689 1.00 52.85 ? 143 LYS H CD 1 ATOM 5225 C CE . LYS C 3 151 ? -41.684 23.125 -49.913 1.00 53.33 ? 143 LYS H CE 1 ATOM 5226 N NZ . LYS C 3 151 ? -41.720 21.810 -50.657 1.00 52.97 ? 143 LYS H NZ 1 ATOM 5227 N N . ASP C 3 152 ? -38.226 27.151 -49.330 1.00 36.95 ? 144 ASP H N 1 ATOM 5228 C CA . ASP C 3 152 ? -36.837 26.696 -49.274 1.00 35.72 ? 144 ASP H CA 1 ATOM 5229 C C . ASP C 3 152 ? -35.895 27.717 -49.912 1.00 40.71 ? 144 ASP H C 1 ATOM 5230 O O . ASP C 3 152 ? -35.250 27.413 -50.926 1.00 37.75 ? 144 ASP H O 1 ATOM 5231 C CB . ASP C 3 152 ? -36.715 25.342 -50.000 1.00 41.38 ? 144 ASP H CB 1 ATOM 5232 C CG . ASP C 3 152 ? -37.340 24.175 -49.218 1.00 50.45 ? 144 ASP H CG 1 ATOM 5233 O OD1 . ASP C 3 152 ? -37.378 24.208 -47.980 1.00 49.02 ? 144 ASP H OD1 1 ATOM 5234 O OD2 . ASP C 3 152 ? -37.761 23.189 -49.852 1.00 56.41 ? 144 ASP H OD2 1 ATOM 5235 N N . TYR C 3 153 ? -35.814 28.930 -49.336 1.00 34.49 ? 145 TYR H N 1 ATOM 5236 C CA . TYR C 3 153 ? -34.856 29.914 -49.835 1.00 27.94 ? 145 TYR H CA 1 ATOM 5237 C C . TYR C 3 153 ? -33.882 30.343 -48.691 1.00 26.19 ? 145 TYR H C 1 ATOM 5238 O O . TYR C 3 153 ? -34.147 30.112 -47.520 1.00 29.23 ? 145 TYR H O 1 ATOM 5239 C CB . TYR C 3 153 ? -35.569 31.136 -50.418 1.00 30.37 ? 145 TYR H CB 1 ATOM 5240 C CG . TYR C 3 153 ? -36.352 31.948 -49.381 1.00 35.49 ? 145 TYR H CG 1 ATOM 5241 C CD1 . TYR C 3 153 ? -35.741 33.021 -48.716 1.00 35.85 ? 145 TYR H CD1 1 ATOM 5242 C CD2 . TYR C 3 153 ? -37.688 31.649 -49.069 1.00 38.24 ? 145 TYR H CD2 1 ATOM 5243 C CE1 . TYR C 3 153 ? -36.439 33.762 -47.762 1.00 35.33 ? 145 TYR H CE1 1 ATOM 5244 C CE2 . TYR C 3 153 ? -38.397 32.392 -48.128 1.00 38.48 ? 145 TYR H CE2 1 ATOM 5245 C CZ . TYR C 3 153 ? -37.760 33.453 -47.477 1.00 39.90 ? 145 TYR H CZ 1 ATOM 5246 O OH . TYR C 3 153 ? -38.446 34.208 -46.546 1.00 36.32 ? 145 TYR H OH 1 ATOM 5247 N N . PHE C 3 154 ? -32.771 30.928 -49.094 1.00 31.36 ? 146 PHE H N 1 ATOM 5248 C CA . PHE C 3 154 ? -31.810 31.461 -48.152 1.00 28.01 ? 146 PHE H CA 1 ATOM 5249 C C . PHE C 3 154 ? -30.944 32.452 -48.881 1.00 34.11 ? 146 PHE H C 1 ATOM 5250 O O . PHE C 3 154 ? -30.507 32.203 -50.027 1.00 32.07 ? 146 PHE H O 1 ATOM 5251 C CB . PHE C 3 154 ? -30.953 30.361 -47.507 1.00 30.32 ? 146 PHE H CB 1 ATOM 5252 C CG . PHE C 3 154 ? -29.902 30.932 -46.575 1.00 27.08 ? 146 PHE H CG 1 ATOM 5253 C CD1 . PHE C 3 154 ? -30.208 31.167 -45.256 1.00 29.77 ? 146 PHE H CD1 1 ATOM 5254 C CD2 . PHE C 3 154 ? -28.677 31.364 -47.080 1.00 28.53 ? 146 PHE H CD2 1 ATOM 5255 C CE1 . PHE C 3 154 ? -29.283 31.752 -44.389 1.00 28.78 ? 146 PHE H CE1 1 ATOM 5256 C CE2 . PHE C 3 154 ? -27.733 31.954 -46.235 1.00 30.49 ? 146 PHE H CE2 1 ATOM 5257 C CZ . PHE C 3 154 ? -28.039 32.153 -44.879 1.00 29.07 ? 146 PHE H CZ 1 ATOM 5258 N N . PRO C 3 155 ? -30.668 33.606 -48.234 1.00 28.77 ? 147 PRO H N 1 ATOM 5259 C CA . PRO C 3 155 ? -31.132 34.072 -46.915 1.00 30.68 ? 147 PRO H CA 1 ATOM 5260 C C . PRO C 3 155 ? -32.364 34.965 -47.073 1.00 32.95 ? 147 PRO H C 1 ATOM 5261 O O . PRO C 3 155 ? -32.830 35.158 -48.221 1.00 31.01 ? 147 PRO H O 1 ATOM 5262 C CB . PRO C 3 155 ? -29.950 34.934 -46.439 1.00 28.42 ? 147 PRO H CB 1 ATOM 5263 C CG . PRO C 3 155 ? -29.523 35.647 -47.769 1.00 28.72 ? 147 PRO H CG 1 ATOM 5264 C CD . PRO C 3 155 ? -29.674 34.524 -48.840 1.00 29.47 ? 147 PRO H CD 1 ATOM 5265 N N . GLU C 3 156 ? -32.900 35.482 -45.967 1.00 31.81 ? 148 GLU H N 1 ATOM 5266 C CA . GLU C 3 156 ? -33.860 36.577 -46.046 1.00 35.58 ? 148 GLU H CA 1 ATOM 5267 C C . GLU C 3 156 ? -33.201 37.743 -46.733 1.00 41.32 ? 148 GLU H C 1 ATOM 5268 O O . GLU C 3 156 ? -31.972 37.874 -46.683 1.00 35.03 ? 148 GLU H O 1 ATOM 5269 C CB . GLU C 3 156 ? -34.275 37.021 -44.630 1.00 33.46 ? 148 GLU H CB 1 ATOM 5270 C CG . GLU C 3 156 ? -35.075 35.985 -43.934 1.00 29.44 ? 148 GLU H CG 1 ATOM 5271 C CD . GLU C 3 156 ? -36.555 36.101 -44.246 1.00 44.01 ? 148 GLU H CD 1 ATOM 5272 O OE1 . GLU C 3 156 ? -36.934 36.220 -45.434 1.00 37.46 ? 148 GLU H OE1 1 ATOM 5273 O OE2 . GLU C 3 156 ? -37.343 36.069 -43.282 1.00 38.40 ? 148 GLU H OE2 1 ATOM 5274 N N . PRO C 3 157 ? -34.000 38.627 -47.357 1.00 36.42 ? 149 PRO H N 1 ATOM 5275 C CA . PRO C 3 157 ? -35.460 38.558 -47.441 1.00 40.69 ? 149 PRO H CA 1 ATOM 5276 C C . PRO C 3 157 ? -35.976 38.210 -48.825 1.00 43.18 ? 149 PRO H C 1 ATOM 5277 O O . PRO C 3 157 ? -35.246 38.189 -49.804 1.00 37.62 ? 149 PRO H O 1 ATOM 5278 C CB . PRO C 3 157 ? -35.879 40.007 -47.178 1.00 34.28 ? 149 PRO H CB 1 ATOM 5279 C CG . PRO C 3 157 ? -34.775 40.803 -47.858 1.00 42.20 ? 149 PRO H CG 1 ATOM 5280 C CD . PRO C 3 157 ? -33.491 39.922 -47.822 1.00 38.39 ? 149 PRO H CD 1 ATOM 5281 N N . VAL C 3 158 ? -37.279 37.993 -48.888 1.00 40.52 ? 150 VAL H N 1 ATOM 5282 C CA . VAL C 3 158 ? -37.986 37.828 -50.147 1.00 39.94 ? 150 VAL H CA 1 ATOM 5283 C C . VAL C 3 158 ? -38.989 38.965 -50.221 1.00 42.65 ? 150 VAL H C 1 ATOM 5284 O O . VAL C 3 158 ? -39.548 39.323 -49.179 1.00 43.17 ? 150 VAL H O 1 ATOM 5285 C CB . VAL C 3 158 ? -38.736 36.493 -50.104 1.00 38.77 ? 150 VAL H CB 1 ATOM 5286 C CG1 . VAL C 3 158 ? -39.968 36.526 -51.001 1.00 46.61 ? 150 VAL H CG1 1 ATOM 5287 C CG2 . VAL C 3 158 ? -37.752 35.339 -50.530 1.00 35.21 ? 150 VAL H CG2 1 ATOM 5288 N N . THR C 3 159 ? -39.222 39.540 -51.411 1.00 40.43 ? 151 THR H N 1 ATOM 5289 C CA . THR C 3 159 ? -40.381 40.449 -51.556 1.00 45.39 ? 151 THR H CA 1 ATOM 5290 C C . THR C 3 159 ? -41.458 39.788 -52.398 1.00 47.02 ? 151 THR H C 1 ATOM 5291 O O . THR C 3 159 ? -41.166 39.113 -53.388 1.00 46.85 ? 151 THR H O 1 ATOM 5292 C CB . THR C 3 159 ? -40.015 41.830 -52.137 1.00 43.85 ? 151 THR H CB 1 ATOM 5293 O OG1 . THR C 3 159 ? -39.465 41.681 -53.451 1.00 51.71 ? 151 THR H OG1 1 ATOM 5294 C CG2 . THR C 3 159 ? -38.986 42.510 -51.252 1.00 45.58 ? 151 THR H CG2 1 ATOM 5295 N N . VAL C 3 160 ? -42.701 39.948 -51.980 1.00 42.11 ? 152 VAL H N 1 ATOM 5296 C CA . VAL C 3 160 ? -43.815 39.427 -52.746 1.00 44.27 ? 152 VAL H CA 1 ATOM 5297 C C . VAL C 3 160 ? -44.775 40.562 -53.089 1.00 51.25 ? 152 VAL H C 1 ATOM 5298 O O . VAL C 3 160 ? -45.196 41.309 -52.208 1.00 49.35 ? 152 VAL H O 1 ATOM 5299 C CB . VAL C 3 160 ? -44.590 38.366 -51.972 1.00 44.38 ? 152 VAL H CB 1 ATOM 5300 C CG1 . VAL C 3 160 ? -45.622 37.690 -52.916 1.00 41.36 ? 152 VAL H CG1 1 ATOM 5301 C CG2 . VAL C 3 160 ? -43.632 37.347 -51.392 1.00 51.63 ? 152 VAL H CG2 1 ATOM 5302 N N . SER C 3 161 ? -45.107 40.686 -54.373 1.00 54.97 ? 153 SER H N 1 ATOM 5303 C CA . SER C 3 161 ? -46.159 41.598 -54.809 1.00 43.37 ? 153 SER H CA 1 ATOM 5304 C C . SER C 3 161 ? -47.239 40.794 -55.533 1.00 54.41 ? 153 SER H C 1 ATOM 5305 O O . SER C 3 161 ? -47.023 39.637 -55.916 1.00 45.21 ? 153 SER H O 1 ATOM 5306 C CB . SER C 3 161 ? -45.583 42.682 -55.723 1.00 58.61 ? 153 SER H CB 1 ATOM 5307 O OG . SER C 3 161 ? -45.044 42.115 -56.914 1.00 52.38 ? 153 SER H OG 1 ATOM 5308 N N . TRP C 3 162 ? -48.407 41.407 -55.698 1.00 55.17 ? 154 TRP H N 1 ATOM 5309 C CA . TRP C 3 162 ? -49.498 40.792 -56.459 1.00 53.52 ? 154 TRP H CA 1 ATOM 5310 C C . TRP C 3 162 ? -49.877 41.618 -57.683 1.00 46.96 ? 154 TRP H C 1 ATOM 5311 O O . TRP C 3 162 ? -49.925 42.848 -57.634 1.00 49.86 ? 154 TRP H O 1 ATOM 5312 C CB . TRP C 3 162 ? -50.713 40.552 -55.579 1.00 45.74 ? 154 TRP H CB 1 ATOM 5313 C CG . TRP C 3 162 ? -50.505 39.484 -54.601 1.00 45.80 ? 154 TRP H CG 1 ATOM 5314 C CD1 . TRP C 3 162 ? -49.996 39.631 -53.332 1.00 49.07 ? 154 TRP H CD1 1 ATOM 5315 C CD2 . TRP C 3 162 ? -50.787 38.079 -54.760 1.00 47.73 ? 154 TRP H CD2 1 ATOM 5316 N NE1 . TRP C 3 162 ? -49.949 38.414 -52.698 1.00 48.07 ? 154 TRP H NE1 1 ATOM 5317 C CE2 . TRP C 3 162 ? -50.425 37.443 -53.546 1.00 46.38 ? 154 TRP H CE2 1 ATOM 5318 C CE3 . TRP C 3 162 ? -51.297 37.294 -55.807 1.00 47.09 ? 154 TRP H CE3 1 ATOM 5319 C CZ2 . TRP C 3 162 ? -50.570 36.050 -53.345 1.00 43.73 ? 154 TRP H CZ2 1 ATOM 5320 C CZ3 . TRP C 3 162 ? -51.431 35.907 -55.610 1.00 47.38 ? 154 TRP H CZ3 1 ATOM 5321 C CH2 . TRP C 3 162 ? -51.068 35.305 -54.394 1.00 53.05 ? 154 TRP H CH2 1 ATOM 5322 N N . ASN C 3 163 ? -50.096 40.925 -58.799 1.00 53.41 ? 155 ASN H N 1 ATOM 5323 C CA . ASN C 3 163 ? -50.398 41.607 -60.047 1.00 52.70 ? 155 ASN H CA 1 ATOM 5324 C C . ASN C 3 163 ? -49.442 42.783 -60.329 1.00 60.32 ? 155 ASN H C 1 ATOM 5325 O O . ASN C 3 163 ? -49.871 43.912 -60.602 1.00 56.39 ? 155 ASN H O 1 ATOM 5326 C CB . ASN C 3 163 ? -51.870 42.038 -60.044 1.00 57.25 ? 155 ASN H CB 1 ATOM 5327 C CG . ASN C 3 163 ? -52.821 40.843 -59.992 1.00 56.47 ? 155 ASN H CG 1 ATOM 5328 O OD1 . ASN C 3 163 ? -52.381 39.690 -59.952 1.00 54.52 ? 155 ASN H OD1 1 ATOM 5329 N ND2 . ASN C 3 163 ? -54.128 41.116 -59.994 1.00 56.75 ? 155 ASN H ND2 1 ATOM 5330 N N . SER C 3 164 ? -48.141 42.514 -60.227 1.00 54.89 ? 156 SER H N 1 ATOM 5331 C CA . SER C 3 164 ? -47.096 43.519 -60.516 1.00 48.02 ? 156 SER H CA 1 ATOM 5332 C C . SER C 3 164 ? -47.210 44.802 -59.689 1.00 58.50 ? 156 SER H C 1 ATOM 5333 O O . SER C 3 164 ? -46.781 45.877 -60.131 1.00 62.13 ? 156 SER H O 1 ATOM 5334 C CB . SER C 3 164 ? -47.019 43.851 -62.015 1.00 50.68 ? 156 SER H CB 1 ATOM 5335 O OG . SER C 3 164 ? -46.945 42.664 -62.792 1.00 53.02 ? 156 SER H OG 1 ATOM 5336 N N . GLY C 3 165 ? -47.779 44.676 -58.492 1.00 54.64 ? 157 GLY H N 1 ATOM 5337 C CA . GLY C 3 165 ? -47.890 45.794 -57.572 1.00 64.28 ? 157 GLY H CA 1 ATOM 5338 C C . GLY C 3 165 ? -49.245 46.474 -57.632 1.00 67.82 ? 157 GLY H C 1 ATOM 5339 O O . GLY C 3 165 ? -49.543 47.387 -56.849 1.00 64.36 ? 157 GLY H O 1 ATOM 5340 N N . ALA C 3 166 ? -50.078 46.017 -58.561 1.00 59.93 ? 158 ALA H N 1 ATOM 5341 C CA . ALA C 3 166 ? -51.379 46.640 -58.789 1.00 75.20 ? 158 ALA H CA 1 ATOM 5342 C C . ALA C 3 166 ? -52.380 46.285 -57.694 1.00 67.42 ? 158 ALA H C 1 ATOM 5343 O O . ALA C 3 166 ? -53.292 47.067 -57.399 1.00 65.63 ? 158 ALA H O 1 ATOM 5344 C CB . ALA C 3 166 ? -51.928 46.254 -60.164 1.00 75.26 ? 158 ALA H CB 1 ATOM 5345 N N . LEU C 3 167 ? -52.209 45.108 -57.096 1.00 57.16 ? 159 LEU H N 1 ATOM 5346 C CA . LEU C 3 167 ? -53.099 44.679 -56.023 1.00 63.39 ? 159 LEU H CA 1 ATOM 5347 C C . LEU C 3 167 ? -52.385 44.746 -54.685 1.00 67.82 ? 159 LEU H C 1 ATOM 5348 O O . LEU C 3 167 ? -51.520 43.915 -54.408 1.00 57.25 ? 159 LEU H O 1 ATOM 5349 C CB . LEU C 3 167 ? -53.615 43.264 -56.273 1.00 48.13 ? 159 LEU H CB 1 ATOM 5350 C CG . LEU C 3 167 ? -54.525 42.636 -55.213 1.00 59.83 ? 159 LEU H CG 1 ATOM 5351 C CD1 . LEU C 3 167 ? -55.782 43.473 -54.965 1.00 69.49 ? 159 LEU H CD1 1 ATOM 5352 C CD2 . LEU C 3 167 ? -54.906 41.221 -55.615 1.00 53.37 ? 159 LEU H CD2 1 ATOM 5353 N N . THR C 3 168 ? -52.748 45.738 -53.868 1.00 66.67 ? 160 THR H N 1 ATOM 5354 C CA . THR C 3 168 ? -52.149 45.920 -52.550 1.00 62.12 ? 160 THR H CA 1 ATOM 5355 C C . THR C 3 168 ? -53.127 45.594 -51.401 1.00 74.22 ? 160 THR H C 1 ATOM 5356 O O . THR C 3 168 ? -52.708 45.141 -50.327 1.00 73.14 ? 160 THR H O 1 ATOM 5357 C CB . THR C 3 168 ? -51.542 47.353 -52.373 1.00 64.18 ? 160 THR H CB 1 ATOM 5358 O OG1 . THR C 3 168 ? -52.537 48.343 -52.674 1.00 68.46 ? 160 THR H OG1 1 ATOM 5359 C CG2 . THR C 3 168 ? -50.334 47.552 -53.288 1.00 60.12 ? 160 THR H CG2 1 ATOM 5360 N N . SER C 3 169 ? -54.422 45.809 -51.640 1.00 66.97 ? 161 SER H N 1 ATOM 5361 C CA . SER C 3 169 ? -55.466 45.589 -50.627 1.00 67.08 ? 161 SER H CA 1 ATOM 5362 C C . SER C 3 169 ? -55.723 44.115 -50.260 1.00 65.86 ? 161 SER H C 1 ATOM 5363 O O . SER C 3 169 ? -55.884 43.256 -51.135 1.00 70.70 ? 161 SER H O 1 ATOM 5364 C CB . SER C 3 169 ? -56.785 46.208 -51.101 1.00 78.90 ? 161 SER H CB 1 ATOM 5365 O OG . SER C 3 169 ? -57.369 45.412 -52.126 1.00 74.37 ? 161 SER H OG 1 ATOM 5366 N N . GLY C 3 170 ? -55.791 43.833 -48.963 1.00 63.27 ? 162 GLY H N 1 ATOM 5367 C CA . GLY C 3 170 ? -56.123 42.496 -48.501 1.00 67.02 ? 162 GLY H CA 1 ATOM 5368 C C . GLY C 3 170 ? -54.931 41.558 -48.552 1.00 60.21 ? 162 GLY H C 1 ATOM 5369 O O . GLY C 3 170 ? -55.057 40.366 -48.308 1.00 55.20 ? 162 GLY H O 1 ATOM 5370 N N . VAL C 3 171 ? -53.767 42.114 -48.860 1.00 60.05 ? 163 VAL H N 1 ATOM 5371 C CA . VAL C 3 171 ? -52.527 41.344 -48.909 1.00 53.42 ? 163 VAL H CA 1 ATOM 5372 C C . VAL C 3 171 ? -51.868 41.210 -47.532 1.00 63.04 ? 163 VAL H C 1 ATOM 5373 O O . VAL C 3 171 ? -51.611 42.221 -46.861 1.00 57.11 ? 163 VAL H O 1 ATOM 5374 C CB . VAL C 3 171 ? -51.504 42.006 -49.854 1.00 50.77 ? 163 VAL H CB 1 ATOM 5375 C CG1 . VAL C 3 171 ? -50.253 41.154 -49.946 1.00 49.48 ? 163 VAL H CG1 1 ATOM 5376 C CG2 . VAL C 3 171 ? -52.113 42.205 -51.245 1.00 54.69 ? 163 VAL H CG2 1 ATOM 5377 N N . HIS C 3 172 ? -51.571 39.968 -47.140 1.00 52.42 ? 164 HIS H N 1 ATOM 5378 C CA . HIS C 3 172 ? -50.916 39.672 -45.868 1.00 55.17 ? 164 HIS H CA 1 ATOM 5379 C C . HIS C 3 172 ? -49.739 38.718 -46.100 1.00 52.33 ? 164 HIS H C 1 ATOM 5380 O O . HIS C 3 172 ? -49.940 37.512 -46.206 1.00 52.47 ? 164 HIS H O 1 ATOM 5381 C CB . HIS C 3 172 ? -51.927 39.010 -44.915 1.00 56.21 ? 164 HIS H CB 1 ATOM 5382 C CG . HIS C 3 172 ? -51.433 38.831 -43.505 1.00 68.19 ? 164 HIS H CG 1 ATOM 5383 N ND1 . HIS C 3 172 ? -50.199 39.281 -43.070 1.00 60.53 ? 164 HIS H ND1 1 ATOM 5384 C CD2 . HIS C 3 172 ? -52.020 38.250 -42.429 1.00 57.29 ? 164 HIS H CD2 1 ATOM 5385 C CE1 . HIS C 3 172 ? -50.046 38.978 -41.790 1.00 51.08 ? 164 HIS H CE1 1 ATOM 5386 N NE2 . HIS C 3 172 ? -51.138 38.354 -41.378 1.00 66.06 ? 164 HIS H NE2 1 ATOM 5387 N N . THR C 3 173 ? -48.516 39.241 -46.160 1.00 50.32 ? 165 THR H N 1 ATOM 5388 C CA . THR C 3 173 ? -47.347 38.369 -46.300 1.00 43.85 ? 165 THR H CA 1 ATOM 5389 C C . THR C 3 173 ? -46.820 38.011 -44.906 1.00 41.39 ? 165 THR H C 1 ATOM 5390 O O . THR C 3 173 ? -46.404 38.882 -44.142 1.00 46.47 ? 165 THR H O 1 ATOM 5391 C CB . THR C 3 173 ? -46.248 39.026 -47.174 1.00 53.64 ? 165 THR H CB 1 ATOM 5392 O OG1 . THR C 3 173 ? -46.817 39.475 -48.415 1.00 48.42 ? 165 THR H OG1 1 ATOM 5393 C CG2 . THR C 3 173 ? -45.088 38.029 -47.458 1.00 42.87 ? 165 THR H CG2 1 ATOM 5394 N N . PHE C 3 174 ? -46.852 36.735 -44.568 1.00 38.16 ? 166 PHE H N 1 ATOM 5395 C CA . PHE C 3 174 ? -46.511 36.281 -43.230 1.00 40.85 ? 166 PHE H CA 1 ATOM 5396 C C . PHE C 3 174 ? -44.990 36.207 -43.038 1.00 44.20 ? 166 PHE H C 1 ATOM 5397 O O . PHE C 3 174 ? -44.250 35.910 -43.988 1.00 41.47 ? 166 PHE H O 1 ATOM 5398 C CB . PHE C 3 174 ? -47.101 34.897 -42.980 1.00 34.73 ? 166 PHE H CB 1 ATOM 5399 C CG . PHE C 3 174 ? -48.570 34.916 -42.699 1.00 53.81 ? 166 PHE H CG 1 ATOM 5400 C CD1 . PHE C 3 174 ? -49.478 35.266 -43.698 1.00 51.20 ? 166 PHE H CD1 1 ATOM 5401 C CD2 . PHE C 3 174 ? -49.051 34.580 -41.441 1.00 47.51 ? 166 PHE H CD2 1 ATOM 5402 C CE1 . PHE C 3 174 ? -50.849 35.280 -43.439 1.00 45.63 ? 166 PHE H CE1 1 ATOM 5403 C CE2 . PHE C 3 174 ? -50.427 34.587 -41.178 1.00 50.63 ? 166 PHE H CE2 1 ATOM 5404 C CZ . PHE C 3 174 ? -51.319 34.937 -42.170 1.00 49.83 ? 166 PHE H CZ 1 ATOM 5405 N N . PRO C 3 175 ? -44.513 36.482 -41.809 1.00 41.66 ? 167 PRO H N 1 ATOM 5406 C CA . PRO C 3 175 ? -43.075 36.267 -41.570 1.00 33.08 ? 167 PRO H CA 1 ATOM 5407 C C . PRO C 3 175 ? -42.681 34.803 -41.844 1.00 34.42 ? 167 PRO H C 1 ATOM 5408 O O . PRO C 3 175 ? -43.412 33.859 -41.494 1.00 35.61 ? 167 PRO H O 1 ATOM 5409 C CB . PRO C 3 175 ? -42.915 36.559 -40.056 1.00 36.79 ? 167 PRO H CB 1 ATOM 5410 C CG . PRO C 3 175 ? -44.009 37.585 -39.741 1.00 33.64 ? 167 PRO H CG 1 ATOM 5411 C CD . PRO C 3 175 ? -45.201 37.077 -40.643 1.00 40.96 ? 167 PRO H CD 1 ATOM 5412 N N . ALA C 3 176 ? -41.495 34.635 -42.431 1.00 39.36 ? 168 ALA H N 1 ATOM 5413 C CA . ALA C 3 176 ? -40.941 33.318 -42.731 1.00 36.48 ? 168 ALA H CA 1 ATOM 5414 C C . ALA C 3 176 ? -40.730 32.424 -41.522 1.00 37.42 ? 168 ALA H C 1 ATOM 5415 O O . ALA C 3 176 ? -40.479 32.877 -40.393 1.00 41.57 ? 168 ALA H O 1 ATOM 5416 C CB . ALA C 3 176 ? -39.620 33.482 -43.521 1.00 35.29 ? 168 ALA H CB 1 ATOM 5417 N N . VAL C 3 177 ? -40.828 31.127 -41.746 1.00 31.34 ? 169 VAL H N 1 ATOM 5418 C CA . VAL C 3 177 ? -40.388 30.177 -40.746 1.00 31.59 ? 169 VAL H CA 1 ATOM 5419 C C . VAL C 3 177 ? -38.949 29.742 -41.123 1.00 30.34 ? 169 VAL H C 1 ATOM 5420 O O . VAL C 3 177 ? -38.605 29.684 -42.307 1.00 33.62 ? 169 VAL H O 1 ATOM 5421 C CB . VAL C 3 177 ? -41.287 28.933 -40.678 1.00 45.80 ? 169 VAL H CB 1 ATOM 5422 C CG1 . VAL C 3 177 ? -41.229 28.132 -42.006 1.00 36.26 ? 169 VAL H CG1 1 ATOM 5423 C CG2 . VAL C 3 177 ? -40.872 28.064 -39.520 1.00 43.58 ? 169 VAL H CG2 1 ATOM 5424 N N . LEU C 3 178 ? -38.107 29.552 -40.127 1.00 34.30 ? 170 LEU H N 1 ATOM 5425 C CA . LEU C 3 178 ? -36.727 29.127 -40.389 1.00 34.15 ? 170 LEU H CA 1 ATOM 5426 C C . LEU C 3 178 ? -36.674 27.631 -40.087 1.00 33.58 ? 170 LEU H C 1 ATOM 5427 O O . LEU C 3 178 ? -36.841 27.217 -38.935 1.00 35.98 ? 170 LEU H O 1 ATOM 5428 C CB . LEU C 3 178 ? -35.714 29.886 -39.504 1.00 35.77 ? 170 LEU H CB 1 ATOM 5429 C CG . LEU C 3 178 ? -34.254 29.366 -39.565 1.00 33.77 ? 170 LEU H CG 1 ATOM 5430 C CD1 . LEU C 3 178 ? -33.663 29.379 -40.981 1.00 33.21 ? 170 LEU H CD1 1 ATOM 5431 C CD2 . LEU C 3 178 ? -33.380 30.251 -38.650 1.00 35.40 ? 170 LEU H CD2 1 ATOM 5432 N N . GLN C 3 179 ? -36.465 26.816 -41.120 1.00 40.56 ? 171 GLN H N 1 ATOM 5433 C CA . GLN C 3 179 ? -36.492 25.358 -40.941 1.00 43.17 ? 171 GLN H CA 1 ATOM 5434 C C . GLN C 3 179 ? -35.224 24.851 -40.285 1.00 46.25 ? 171 GLN H C 1 ATOM 5435 O O . GLN C 3 179 ? -34.204 25.522 -40.273 1.00 39.07 ? 171 GLN H O 1 ATOM 5436 C CB . GLN C 3 179 ? -36.653 24.636 -42.295 1.00 40.37 ? 171 GLN H CB 1 ATOM 5437 C CG . GLN C 3 179 ? -37.866 25.040 -43.067 1.00 36.84 ? 171 GLN H CG 1 ATOM 5438 C CD . GLN C 3 179 ? -37.704 24.814 -44.571 1.00 49.48 ? 171 GLN H CD 1 ATOM 5439 O OE1 . GLN C 3 179 ? -37.917 25.733 -45.380 1.00 46.22 ? 171 GLN H OE1 1 ATOM 5440 N NE2 . GLN C 3 179 ? -37.318 23.593 -44.957 1.00 55.71 ? 171 GLN H NE2 1 ATOM 5441 N N . SER C 3 180 ? -35.256 23.614 -39.799 1.00 42.86 ? 172 SER H N 1 ATOM 5442 C CA . SER C 3 180 ? -34.045 23.007 -39.253 1.00 41.37 ? 172 SER H CA 1 ATOM 5443 C C . SER C 3 180 ? -32.989 22.795 -40.355 1.00 40.97 ? 172 SER H C 1 ATOM 5444 O O . SER C 3 180 ? -31.802 22.666 -40.050 1.00 48.01 ? 172 SER H O 1 ATOM 5445 C CB . SER C 3 180 ? -34.388 21.677 -38.569 1.00 53.12 ? 172 SER H CB 1 ATOM 5446 O OG . SER C 3 180 ? -34.927 20.773 -39.530 1.00 54.20 ? 172 SER H OG 1 ATOM 5447 N N . SER C 3 181 ? -33.408 22.785 -41.625 1.00 37.96 ? 173 SER H N 1 ATOM 5448 C CA . SER C 3 181 ? -32.459 22.678 -42.726 1.00 34.62 ? 173 SER H CA 1 ATOM 5449 C C . SER C 3 181 ? -31.567 23.917 -42.809 1.00 43.26 ? 173 SER H C 1 ATOM 5450 O O . SER C 3 181 ? -30.439 23.863 -43.300 1.00 40.47 ? 173 SER H O 1 ATOM 5451 C CB . SER C 3 181 ? -33.185 22.534 -44.056 1.00 39.44 ? 173 SER H CB 1 ATOM 5452 O OG . SER C 3 181 ? -34.002 23.654 -44.387 1.00 39.43 ? 173 SER H OG 1 ATOM 5453 N N . GLY C 3 182 ? -32.112 25.039 -42.360 1.00 38.66 ? 174 GLY H N 1 ATOM 5454 C CA . GLY C 3 182 ? -31.414 26.308 -42.426 1.00 41.85 ? 174 GLY H CA 1 ATOM 5455 C C . GLY C 3 182 ? -32.042 27.174 -43.491 1.00 37.62 ? 174 GLY H C 1 ATOM 5456 O O . GLY C 3 182 ? -31.627 28.314 -43.714 1.00 31.74 ? 174 GLY H O 1 ATOM 5457 N N . LEU C 3 183 ? -33.040 26.641 -44.178 1.00 31.80 ? 175 LEU H N 1 ATOM 5458 C CA . LEU C 3 183 ? -33.707 27.425 -45.203 1.00 31.36 ? 175 LEU H CA 1 ATOM 5459 C C . LEU C 3 183 ? -34.995 28.029 -44.664 1.00 25.49 ? 175 LEU H C 1 ATOM 5460 O O . LEU C 3 183 ? -35.569 27.522 -43.704 1.00 39.28 ? 175 LEU H O 1 ATOM 5461 C CB . LEU C 3 183 ? -34.062 26.536 -46.410 1.00 35.46 ? 175 LEU H CB 1 ATOM 5462 C CG . LEU C 3 183 ? -32.922 25.773 -47.075 1.00 39.46 ? 175 LEU H CG 1 ATOM 5463 C CD1 . LEU C 3 183 ? -33.508 24.987 -48.282 1.00 35.81 ? 175 LEU H CD1 1 ATOM 5464 C CD2 . LEU C 3 183 ? -31.802 26.715 -47.508 1.00 36.49 ? 175 LEU H CD2 1 ATOM 5465 N N . TYR C 3 184 ? -35.471 29.086 -45.329 1.00 33.34 ? 176 TYR H N 1 ATOM 5466 C CA . TYR C 3 184 ? -36.710 29.745 -44.926 1.00 33.08 ? 176 TYR H CA 1 ATOM 5467 C C . TYR C 3 184 ? -37.833 29.328 -45.861 1.00 40.15 ? 176 TYR H C 1 ATOM 5468 O O . TYR C 3 184 ? -37.578 28.905 -46.958 1.00 31.66 ? 176 TYR H O 1 ATOM 5469 C CB . TYR C 3 184 ? -36.567 31.254 -45.051 1.00 30.75 ? 176 TYR H CB 1 ATOM 5470 C CG . TYR C 3 184 ? -35.538 31.809 -44.074 1.00 26.45 ? 176 TYR H CG 1 ATOM 5471 C CD1 . TYR C 3 184 ? -34.184 31.906 -44.445 1.00 29.17 ? 176 TYR H CD1 1 ATOM 5472 C CD2 . TYR C 3 184 ? -35.947 32.272 -42.806 1.00 32.99 ? 176 TYR H CD2 1 ATOM 5473 C CE1 . TYR C 3 184 ? -33.220 32.438 -43.524 1.00 31.60 ? 176 TYR H CE1 1 ATOM 5474 C CE2 . TYR C 3 184 ? -35.002 32.779 -41.875 1.00 30.60 ? 176 TYR H CE2 1 ATOM 5475 C CZ . TYR C 3 184 ? -33.654 32.862 -42.259 1.00 30.02 ? 176 TYR H CZ 1 ATOM 5476 O OH . TYR C 3 184 ? -32.700 33.380 -41.387 1.00 29.61 ? 176 TYR H OH 1 ATOM 5477 N N . SER C 3 185 ? -39.063 29.495 -45.402 1.00 37.32 ? 177 SER H N 1 ATOM 5478 C CA . SER C 3 185 ? -40.246 29.428 -46.253 1.00 36.50 ? 177 SER H CA 1 ATOM 5479 C C . SER C 3 185 ? -41.224 30.450 -45.724 1.00 37.79 ? 177 SER H C 1 ATOM 5480 O O . SER C 3 185 ? -41.318 30.611 -44.510 1.00 42.38 ? 177 SER H O 1 ATOM 5481 C CB . SER C 3 185 ? -40.895 28.061 -46.128 1.00 39.31 ? 177 SER H CB 1 ATOM 5482 O OG . SER C 3 185 ? -40.166 27.103 -46.847 1.00 38.55 ? 177 SER H OG 1 ATOM 5483 N N . LEU C 3 186 ? -41.953 31.119 -46.617 1.00 38.13 ? 178 LEU H N 1 ATOM 5484 C CA . LEU C 3 186 ? -43.051 31.997 -46.191 1.00 32.63 ? 178 LEU H CA 1 ATOM 5485 C C . LEU C 3 186 ? -44.280 31.851 -47.092 1.00 43.50 ? 178 LEU H C 1 ATOM 5486 O O . LEU C 3 186 ? -44.225 31.214 -48.164 1.00 39.67 ? 178 LEU H O 1 ATOM 5487 C CB . LEU C 3 186 ? -42.616 33.461 -46.154 1.00 29.16 ? 178 LEU H CB 1 ATOM 5488 C CG . LEU C 3 186 ? -42.267 34.262 -47.407 1.00 38.33 ? 178 LEU H CG 1 ATOM 5489 C CD1 . LEU C 3 186 ? -43.482 34.588 -48.321 1.00 36.77 ? 178 LEU H CD1 1 ATOM 5490 C CD2 . LEU C 3 186 ? -41.648 35.567 -46.962 1.00 38.41 ? 178 LEU H CD2 1 ATOM 5491 N N . SER C 3 187 ? -45.378 32.463 -46.666 1.00 39.95 ? 179 SER H N 1 ATOM 5492 C CA . SER C 3 187 ? -46.613 32.455 -47.464 1.00 38.08 ? 179 SER H CA 1 ATOM 5493 C C . SER C 3 187 ? -47.139 33.873 -47.593 1.00 49.18 ? 179 SER H C 1 ATOM 5494 O O . SER C 3 187 ? -46.997 34.687 -46.669 1.00 40.80 ? 179 SER H O 1 ATOM 5495 C CB . SER C 3 187 ? -47.673 31.577 -46.824 1.00 38.83 ? 179 SER H CB 1 ATOM 5496 O OG . SER C 3 187 ? -47.272 30.220 -46.802 1.00 49.20 ? 179 SER H OG 1 ATOM 5497 N N . SER C 3 188 ? -47.713 34.188 -48.750 1.00 36.35 ? 180 SER H N 1 ATOM 5498 C CA . SER C 3 188 ? -48.397 35.463 -48.915 1.00 41.68 ? 180 SER H CA 1 ATOM 5499 C C . SER C 3 188 ? -49.835 35.111 -49.289 1.00 52.33 ? 180 SER H C 1 ATOM 5500 O O . SER C 3 188 ? -50.066 34.298 -50.178 1.00 52.30 ? 180 SER H O 1 ATOM 5501 C CB . SER C 3 188 ? -47.752 36.314 -49.999 1.00 44.76 ? 180 SER H CB 1 ATOM 5502 O OG . SER C 3 188 ? -48.370 37.586 -50.066 1.00 41.93 ? 180 SER H OG 1 ATOM 5503 N N . VAL C 3 189 ? -50.801 35.671 -48.578 1.00 46.52 ? 181 VAL H N 1 ATOM 5504 C CA . VAL C 3 189 ? -52.197 35.378 -48.887 1.00 52.14 ? 181 VAL H CA 1 ATOM 5505 C C . VAL C 3 189 ? -52.937 36.696 -49.111 1.00 56.40 ? 181 VAL H C 1 ATOM 5506 O O . VAL C 3 189 ? -52.690 37.688 -48.418 1.00 57.95 ? 181 VAL H O 1 ATOM 5507 C CB . VAL C 3 189 ? -52.861 34.471 -47.804 1.00 52.23 ? 181 VAL H CB 1 ATOM 5508 C CG1 . VAL C 3 189 ? -52.599 35.019 -46.417 1.00 63.45 ? 181 VAL H CG1 1 ATOM 5509 C CG2 . VAL C 3 189 ? -54.354 34.350 -48.043 1.00 58.77 ? 181 VAL H CG2 1 ATOM 5510 N N . VAL C 3 190 ? -53.788 36.734 -50.133 1.00 55.47 ? 182 VAL H N 1 ATOM 5511 C CA . VAL C 3 190 ? -54.613 37.916 -50.364 1.00 64.08 ? 182 VAL H CA 1 ATOM 5512 C C . VAL C 3 190 ? -56.088 37.563 -50.251 1.00 65.68 ? 182 VAL H C 1 ATOM 5513 O O . VAL C 3 190 ? -56.524 36.503 -50.706 1.00 57.80 ? 182 VAL H O 1 ATOM 5514 C CB . VAL C 3 190 ? -54.303 38.628 -51.708 1.00 67.05 ? 182 VAL H CB 1 ATOM 5515 C CG1 . VAL C 3 190 ? -54.274 37.634 -52.852 1.00 63.32 ? 182 VAL H CG1 1 ATOM 5516 C CG2 . VAL C 3 190 ? -55.301 39.765 -51.982 1.00 65.18 ? 182 VAL H CG2 1 ATOM 5517 N N . THR C 3 191 ? -56.835 38.451 -49.598 1.00 67.29 ? 183 THR H N 1 ATOM 5518 C CA . THR C 3 191 ? -58.268 38.285 -49.434 1.00 74.99 ? 183 THR H CA 1 ATOM 5519 C C . THR C 3 191 ? -59.008 39.191 -50.424 1.00 70.99 ? 183 THR H C 1 ATOM 5520 O O . THR C 3 191 ? -58.813 40.410 -50.445 1.00 67.61 ? 183 THR H O 1 ATOM 5521 C CB . THR C 3 191 ? -58.696 38.521 -47.970 1.00 63.76 ? 183 THR H CB 1 ATOM 5522 O OG1 . THR C 3 191 ? -58.025 37.573 -47.128 1.00 64.47 ? 183 THR H OG1 1 ATOM 5523 C CG2 . THR C 3 191 ? -60.197 38.341 -47.812 1.00 65.57 ? 183 THR H CG2 1 ATOM 5524 N N . VAL C 3 192 ? -59.822 38.561 -51.270 1.00 72.82 ? 184 VAL H N 1 ATOM 5525 C CA . VAL C 3 192 ? -60.497 39.236 -52.375 1.00 77.82 ? 184 VAL H CA 1 ATOM 5526 C C . VAL C 3 192 ? -61.969 38.818 -52.430 1.00 84.16 ? 184 VAL H C 1 ATOM 5527 O O . VAL C 3 192 ? -62.341 37.790 -51.851 1.00 74.76 ? 184 VAL H O 1 ATOM 5528 C CB . VAL C 3 192 ? -59.844 38.867 -53.730 1.00 74.90 ? 184 VAL H CB 1 ATOM 5529 C CG1 . VAL C 3 192 ? -58.437 39.438 -53.823 1.00 70.96 ? 184 VAL H CG1 1 ATOM 5530 C CG2 . VAL C 3 192 ? -59.843 37.352 -53.922 1.00 67.13 ? 184 VAL H CG2 1 ATOM 5531 N N . PRO C 3 193 ? -62.811 39.616 -53.121 1.00 84.97 ? 185 PRO H N 1 ATOM 5532 C CA . PRO C 3 193 ? -64.209 39.263 -53.429 1.00 87.11 ? 185 PRO H CA 1 ATOM 5533 C C . PRO C 3 193 ? -64.347 37.990 -54.280 1.00 86.24 ? 185 PRO H C 1 ATOM 5534 O O . PRO C 3 193 ? -63.761 37.933 -55.366 1.00 84.30 ? 185 PRO H O 1 ATOM 5535 C CB . PRO C 3 193 ? -64.701 40.472 -54.238 1.00 79.13 ? 185 PRO H CB 1 ATOM 5536 C CG . PRO C 3 193 ? -63.461 41.229 -54.630 1.00 77.04 ? 185 PRO H CG 1 ATOM 5537 C CD . PRO C 3 193 ? -62.506 41.000 -53.521 1.00 76.40 ? 185 PRO H CD 1 ATOM 5538 N N . SER C 3 194 ? -65.117 37.004 -53.813 1.00 83.55 ? 186 SER H N 1 ATOM 5539 C CA . SER C 3 194 ? -65.212 35.711 -54.510 1.00 82.61 ? 186 SER H CA 1 ATOM 5540 C C . SER C 3 194 ? -65.965 35.781 -55.841 1.00 86.35 ? 186 SER H C 1 ATOM 5541 O O . SER C 3 194 ? -65.855 34.876 -56.679 1.00 79.70 ? 186 SER H O 1 ATOM 5542 C CB . SER C 3 194 ? -65.793 34.621 -53.600 1.00 75.96 ? 186 SER H CB 1 ATOM 5543 O OG . SER C 3 194 ? -66.874 35.106 -52.834 1.00 83.52 ? 186 SER H OG 1 ATOM 5544 N N . SER C 3 195 ? -66.724 36.858 -56.022 1.00 86.52 ? 187 SER H N 1 ATOM 5545 C CA . SER C 3 195 ? -67.354 37.158 -57.302 1.00 86.42 ? 187 SER H CA 1 ATOM 5546 C C . SER C 3 195 ? -66.253 37.418 -58.328 1.00 93.80 ? 187 SER H C 1 ATOM 5547 O O . SER C 3 195 ? -66.280 36.897 -59.449 1.00 86.48 ? 187 SER H O 1 ATOM 5548 C CB . SER C 3 195 ? -68.247 38.396 -57.173 1.00 84.41 ? 187 SER H CB 1 ATOM 5549 O OG . SER C 3 195 ? -67.477 39.567 -56.922 1.00 83.75 ? 187 SER H OG 1 ATOM 5550 N N . SER C 3 196 ? -65.280 38.224 -57.915 1.00 86.45 ? 188 SER H N 1 ATOM 5551 C CA . SER C 3 196 ? -64.125 38.568 -58.733 1.00 96.03 ? 188 SER H CA 1 ATOM 5552 C C . SER C 3 196 ? -63.138 37.402 -58.781 1.00 93.86 ? 188 SER H C 1 ATOM 5553 O O . SER C 3 196 ? -62.059 37.470 -58.191 1.00 96.71 ? 188 SER H O 1 ATOM 5554 C CB . SER C 3 196 ? -63.436 39.803 -58.141 1.00 91.01 ? 188 SER H CB 1 ATOM 5555 O OG . SER C 3 196 ? -62.599 40.437 -59.092 1.00 87.35 ? 188 SER H OG 1 ATOM 5556 N N . LEU C 3 197 ? -63.503 36.340 -59.491 1.00 91.90 ? 189 LEU H N 1 ATOM 5557 C CA . LEU C 3 197 ? -62.743 35.098 -59.437 1.00 89.57 ? 189 LEU H CA 1 ATOM 5558 C C . LEU C 3 197 ? -62.669 34.447 -60.811 1.00 91.26 ? 189 LEU H C 1 ATOM 5559 O O . LEU C 3 197 ? -61.620 33.951 -61.220 1.00 91.83 ? 189 LEU H O 1 ATOM 5560 C CB . LEU C 3 197 ? -63.391 34.156 -58.421 1.00 86.34 ? 189 LEU H CB 1 ATOM 5561 C CG . LEU C 3 197 ? -62.797 32.782 -58.137 1.00 86.11 ? 189 LEU H CG 1 ATOM 5562 C CD1 . LEU C 3 197 ? -62.943 32.497 -56.654 1.00 86.76 ? 189 LEU H CD1 1 ATOM 5563 C CD2 . LEU C 3 197 ? -63.506 31.712 -58.958 1.00 89.13 ? 189 LEU H CD2 1 ATOM 5564 N N . GLY C 3 198 ? -63.796 34.444 -61.514 1.00 94.72 ? 190 GLY H N 1 ATOM 5565 C CA . GLY C 3 198 ? -63.825 34.015 -62.898 1.00 86.29 ? 190 GLY H CA 1 ATOM 5566 C C . GLY C 3 198 ? -63.727 35.216 -63.825 1.00 98.36 ? 190 GLY H C 1 ATOM 5567 O O . GLY C 3 198 ? -64.209 35.172 -64.961 1.00 91.31 ? 190 GLY H O 1 ATOM 5568 N N . THR C 3 199 ? -63.115 36.295 -63.330 1.00 99.76 ? 191 THR H N 1 ATOM 5569 C CA . THR C 3 199 ? -62.896 37.511 -64.121 1.00 95.18 ? 191 THR H CA 1 ATOM 5570 C C . THR C 3 199 ? -61.471 38.035 -63.989 1.00 98.62 ? 191 THR H C 1 ATOM 5571 O O . THR C 3 199 ? -60.705 38.041 -64.958 1.00 96.43 ? 191 THR H O 1 ATOM 5572 C CB . THR C 3 199 ? -63.848 38.649 -63.713 1.00 97.34 ? 191 THR H CB 1 ATOM 5573 O OG1 . THR C 3 199 ? -63.954 38.694 -62.284 1.00 98.05 ? 191 THR H OG1 1 ATOM 5574 C CG2 . THR C 3 199 ? -65.224 38.437 -64.319 1.00 104.80 ? 191 THR H CG2 1 ATOM 5575 N N . GLN C 3 200 ? -61.130 38.488 -62.785 1.00 93.70 ? 192 GLN H N 1 ATOM 5576 C CA . GLN C 3 200 ? -59.794 39.004 -62.506 1.00 84.43 ? 192 GLN H CA 1 ATOM 5577 C C . GLN C 3 200 ? -58.786 37.855 -62.319 1.00 77.57 ? 192 GLN H C 1 ATOM 5578 O O . GLN C 3 200 ? -59.079 36.865 -61.637 1.00 78.77 ? 192 GLN H O 1 ATOM 5579 C CB . GLN C 3 200 ? -59.840 39.917 -61.275 1.00 75.16 ? 192 GLN H CB 1 ATOM 5580 C CG . GLN C 3 200 ? -58.484 40.371 -60.747 1.00 78.80 ? 192 GLN H CG 1 ATOM 5581 C CD . GLN C 3 200 ? -57.787 41.399 -61.637 1.00 80.36 ? 192 GLN H CD 1 ATOM 5582 O OE1 . GLN C 3 200 ? -56.820 41.081 -62.332 1.00 72.92 ? 192 GLN H OE1 1 ATOM 5583 N NE2 . GLN C 3 200 ? -58.260 42.640 -61.596 1.00 76.74 ? 192 GLN H NE2 1 ATOM 5584 N N . THR C 3 201 ? -57.614 37.981 -62.948 1.00 69.58 ? 193 THR H N 1 ATOM 5585 C CA . THR C 3 201 ? -56.524 37.012 -62.763 1.00 78.38 ? 193 THR H CA 1 ATOM 5586 C C . THR C 3 201 ? -55.618 37.382 -61.567 1.00 69.66 ? 193 THR H C 1 ATOM 5587 O O . THR C 3 201 ? -55.385 38.558 -61.281 1.00 62.11 ? 193 THR H O 1 ATOM 5588 C CB . THR C 3 201 ? -55.659 36.818 -64.054 1.00 64.60 ? 193 THR H CB 1 ATOM 5589 O OG1 . THR C 3 201 ? -54.972 38.033 -64.385 1.00 75.25 ? 193 THR H OG1 1 ATOM 5590 C CG2 . THR C 3 201 ? -56.528 36.396 -65.231 1.00 75.36 ? 193 THR H CG2 1 ATOM 5591 N N . TYR C 3 202 ? -55.125 36.375 -60.857 1.00 67.87 ? 194 TYR H N 1 ATOM 5592 C CA . TYR C 3 202 ? -54.257 36.655 -59.718 1.00 70.15 ? 194 TYR H CA 1 ATOM 5593 C C . TYR C 3 202 ? -52.875 36.015 -59.875 1.00 62.54 ? 194 TYR H C 1 ATOM 5594 O O . TYR C 3 202 ? -52.727 34.781 -59.997 1.00 64.62 ? 194 TYR H O 1 ATOM 5595 C CB . TYR C 3 202 ? -54.941 36.302 -58.393 1.00 57.27 ? 194 TYR H CB 1 ATOM 5596 C CG . TYR C 3 202 ? -56.160 37.170 -58.122 1.00 71.60 ? 194 TYR H CG 1 ATOM 5597 C CD1 . TYR C 3 202 ? -56.018 38.535 -57.850 1.00 70.24 ? 194 TYR H CD1 1 ATOM 5598 C CD2 . TYR C 3 202 ? -57.452 36.634 -58.151 1.00 67.72 ? 194 TYR H CD2 1 ATOM 5599 C CE1 . TYR C 3 202 ? -57.127 39.343 -57.607 1.00 69.28 ? 194 TYR H CE1 1 ATOM 5600 C CE2 . TYR C 3 202 ? -58.568 37.433 -57.911 1.00 71.75 ? 194 TYR H CE2 1 ATOM 5601 C CZ . TYR C 3 202 ? -58.402 38.787 -57.637 1.00 79.39 ? 194 TYR H CZ 1 ATOM 5602 O OH . TYR C 3 202 ? -59.504 39.592 -57.393 1.00 69.38 ? 194 TYR H OH 1 ATOM 5603 N N . ILE C 3 203 ? -51.873 36.890 -59.908 1.00 50.61 ? 195 ILE H N 1 ATOM 5604 C CA . ILE C 3 203 ? -50.466 36.487 -60.069 1.00 57.30 ? 195 ILE H CA 1 ATOM 5605 C C . ILE C 3 203 ? -49.609 37.046 -58.922 1.00 56.23 ? 195 ILE H C 1 ATOM 5606 O O . ILE C 3 203 ? -49.655 38.245 -58.615 1.00 49.90 ? 195 ILE H O 1 ATOM 5607 C CB . ILE C 3 203 ? -49.898 36.962 -61.433 1.00 57.34 ? 195 ILE H CB 1 ATOM 5608 C CG1 . ILE C 3 203 ? -50.750 36.395 -62.575 1.00 67.73 ? 195 ILE H CG1 1 ATOM 5609 C CG2 . ILE C 3 203 ? -48.434 36.545 -61.606 1.00 55.60 ? 195 ILE H CG2 1 ATOM 5610 C CD1 . ILE C 3 203 ? -50.428 37.012 -63.933 1.00 64.89 ? 195 ILE H CD1 1 ATOM 5611 N N . CYS C 3 204 ? -48.846 36.178 -58.269 1.00 46.95 ? 196 CYS H N 1 ATOM 5612 C CA . CYS C 3 204 ? -47.893 36.683 -57.290 1.00 51.53 ? 196 CYS H CA 1 ATOM 5613 C C . CYS C 3 204 ? -46.514 36.751 -57.926 1.00 55.54 ? 196 CYS H C 1 ATOM 5614 O O . CYS C 3 204 ? -46.134 35.895 -58.736 1.00 49.31 ? 196 CYS H O 1 ATOM 5615 C CB . CYS C 3 204 ? -47.879 35.830 -56.038 1.00 45.35 ? 196 CYS H CB 1 ATOM 5616 S SG . CYS C 3 204 ? -47.113 34.235 -56.222 1.00 59.24 ? 196 CYS H SG 1 ATOM 5617 N N . ASN C 3 205 ? -45.799 37.810 -57.592 1.00 43.72 ? 197 ASN H N 1 ATOM 5618 C CA . ASN C 3 205 ? -44.451 38.030 -58.096 1.00 49.14 ? 197 ASN H CA 1 ATOM 5619 C C . ASN C 3 205 ? -43.463 37.918 -56.932 1.00 54.45 ? 197 ASN H C 1 ATOM 5620 O O . ASN C 3 205 ? -43.577 38.635 -55.941 1.00 45.52 ? 197 ASN H O 1 ATOM 5621 C CB . ASN C 3 205 ? -44.366 39.410 -58.744 1.00 52.35 ? 197 ASN H CB 1 ATOM 5622 C CG . ASN C 3 205 ? -45.664 39.808 -59.435 1.00 60.38 ? 197 ASN H CG 1 ATOM 5623 O OD1 . ASN C 3 205 ? -46.395 40.686 -58.952 1.00 54.43 ? 197 ASN H OD1 1 ATOM 5624 N ND2 . ASN C 3 205 ? -45.957 39.163 -60.572 1.00 47.57 ? 197 ASN H ND2 1 ATOM 5625 N N . VAL C 3 206 ? -42.513 36.997 -57.031 1.00 50.31 ? 198 VAL H N 1 ATOM 5626 C CA . VAL C 3 206 ? -41.648 36.733 -55.897 1.00 41.13 ? 198 VAL H CA 1 ATOM 5627 C C . VAL C 3 206 ? -40.238 37.124 -56.292 1.00 48.07 ? 198 VAL H C 1 ATOM 5628 O O . VAL C 3 206 ? -39.692 36.603 -57.272 1.00 49.54 ? 198 VAL H O 1 ATOM 5629 C CB . VAL C 3 206 ? -41.735 35.293 -55.468 1.00 43.42 ? 198 VAL H CB 1 ATOM 5630 C CG1 . VAL C 3 206 ? -40.758 35.009 -54.342 1.00 45.20 ? 198 VAL H CG1 1 ATOM 5631 C CG2 . VAL C 3 206 ? -43.155 34.977 -54.999 1.00 37.33 ? 198 VAL H CG2 1 ATOM 5632 N N . ASN C 3 207 ? -39.664 38.083 -55.574 1.00 38.52 ? 199 ASN H N 1 ATOM 5633 C CA . ASN C 3 207 ? -38.295 38.490 -55.865 1.00 42.64 ? 199 ASN H CA 1 ATOM 5634 C C . ASN C 3 207 ? -37.340 38.102 -54.735 1.00 48.94 ? 199 ASN H C 1 ATOM 5635 O O . ASN C 3 207 ? -37.583 38.437 -53.588 1.00 44.45 ? 199 ASN H O 1 ATOM 5636 C CB . ASN C 3 207 ? -38.219 39.987 -56.140 1.00 45.48 ? 199 ASN H CB 1 ATOM 5637 C CG . ASN C 3 207 ? -36.909 40.381 -56.791 1.00 59.58 ? 199 ASN H CG 1 ATOM 5638 O OD1 . ASN C 3 207 ? -36.343 39.618 -57.579 1.00 69.41 ? 199 ASN H OD1 1 ATOM 5639 N ND2 . ASN C 3 207 ? -36.401 41.559 -56.446 1.00 66.07 ? 199 ASN H ND2 1 ATOM 5640 N N . HIS C 3 208 ? -36.276 37.372 -55.080 1.00 46.89 ? 200 HIS H N 1 ATOM 5641 C CA . HIS C 3 208 ? -35.219 37.015 -54.140 1.00 39.12 ? 200 HIS H CA 1 ATOM 5642 C C . HIS C 3 208 ? -33.892 37.539 -54.657 1.00 46.47 ? 200 HIS H C 1 ATOM 5643 O O . HIS C 3 208 ? -33.175 36.871 -55.421 1.00 50.57 ? 200 HIS H O 1 ATOM 5644 C CB . HIS C 3 208 ? -35.130 35.512 -53.928 1.00 42.38 ? 200 HIS H CB 1 ATOM 5645 C CG . HIS C 3 208 ? -34.204 35.107 -52.812 1.00 40.45 ? 200 HIS H CG 1 ATOM 5646 N ND1 . HIS C 3 208 ? -33.127 34.260 -53.008 1.00 41.36 ? 200 HIS H ND1 1 ATOM 5647 C CD2 . HIS C 3 208 ? -34.200 35.424 -51.490 1.00 42.29 ? 200 HIS H CD2 1 ATOM 5648 C CE1 . HIS C 3 208 ? -32.494 34.083 -51.854 1.00 40.04 ? 200 HIS H CE1 1 ATOM 5649 N NE2 . HIS C 3 208 ? -33.131 34.771 -50.915 1.00 37.13 ? 200 HIS H NE2 1 ATOM 5650 N N . LYS C 3 209 ? -33.588 38.753 -54.261 1.00 42.79 ? 201 LYS H N 1 ATOM 5651 C CA . LYS C 3 209 ? -32.363 39.403 -54.713 1.00 47.61 ? 201 LYS H CA 1 ATOM 5652 C C . LYS C 3 209 ? -31.087 38.571 -54.539 1.00 53.34 ? 201 LYS H C 1 ATOM 5653 O O . LYS C 3 209 ? -30.322 38.438 -55.492 1.00 51.86 ? 201 LYS H O 1 ATOM 5654 C CB . LYS C 3 209 ? -32.177 40.770 -54.039 1.00 51.13 ? 201 LYS H CB 1 ATOM 5655 C CG . LYS C 3 209 ? -33.172 41.844 -54.434 1.00 72.41 ? 201 LYS H CG 1 ATOM 5656 C CD . LYS C 3 209 ? -32.675 43.217 -53.967 1.00 73.38 ? 201 LYS H CD 1 ATOM 5657 C CE . LYS C 3 209 ? -33.772 44.030 -53.258 1.00 76.44 ? 201 LYS H CE 1 ATOM 5658 N NZ . LYS C 3 209 ? -33.207 44.951 -52.198 1.00 81.62 ? 201 LYS H NZ 1 ATOM 5659 N N . PRO C 3 210 ? -30.852 38.004 -53.332 1.00 47.04 ? 202 PRO H N 1 ATOM 5660 C CA . PRO C 3 210 ? -29.559 37.330 -53.147 1.00 45.46 ? 202 PRO H CA 1 ATOM 5661 C C . PRO C 3 210 ? -29.259 36.223 -54.169 1.00 48.23 ? 202 PRO H C 1 ATOM 5662 O O . PRO C 3 210 ? -28.090 36.005 -54.487 1.00 41.48 ? 202 PRO H O 1 ATOM 5663 C CB . PRO C 3 210 ? -29.657 36.749 -51.736 1.00 45.89 ? 202 PRO H CB 1 ATOM 5664 C CG . PRO C 3 210 ? -30.646 37.637 -51.036 1.00 49.01 ? 202 PRO H CG 1 ATOM 5665 C CD . PRO C 3 210 ? -31.668 37.976 -52.103 1.00 48.86 ? 202 PRO H CD 1 ATOM 5666 N N . SER C 3 211 ? -30.279 35.559 -54.705 1.00 42.69 ? 203 SER H N 1 ATOM 5667 C CA . SER C 3 211 ? -30.030 34.529 -55.719 1.00 47.56 ? 203 SER H CA 1 ATOM 5668 C C . SER C 3 211 ? -30.360 35.052 -57.128 1.00 48.82 ? 203 SER H C 1 ATOM 5669 O O . SER C 3 211 ? -30.340 34.296 -58.117 1.00 52.66 ? 203 SER H O 1 ATOM 5670 C CB . SER C 3 211 ? -30.850 33.269 -55.391 1.00 42.83 ? 203 SER H CB 1 ATOM 5671 O OG . SER C 3 211 ? -32.237 33.555 -55.500 1.00 41.72 ? 203 SER H OG 1 ATOM 5672 N N . ASN C 3 212 ? -30.644 36.351 -57.201 1.00 45.28 ? 204 ASN H N 1 ATOM 5673 C CA . ASN C 3 212 ? -31.283 36.965 -58.367 1.00 53.68 ? 204 ASN H CA 1 ATOM 5674 C C . ASN C 3 212 ? -32.410 36.127 -58.980 1.00 53.20 ? 204 ASN H C 1 ATOM 5675 O O . ASN C 3 212 ? -32.430 35.880 -60.176 1.00 61.20 ? 204 ASN H O 1 ATOM 5676 C CB . ASN C 3 212 ? -30.258 37.351 -59.429 1.00 63.45 ? 204 ASN H CB 1 ATOM 5677 C CG . ASN C 3 212 ? -30.821 38.338 -60.420 1.00 74.98 ? 204 ASN H CG 1 ATOM 5678 O OD1 . ASN C 3 212 ? -31.239 37.960 -61.517 1.00 83.66 ? 204 ASN H OD1 1 ATOM 5679 N ND2 . ASN C 3 212 ? -30.880 39.611 -60.025 1.00 81.29 ? 204 ASN H ND2 1 ATOM 5680 N N . THR C 3 213 ? -33.329 35.672 -58.140 1.00 48.32 ? 205 THR H N 1 ATOM 5681 C CA . THR C 3 213 ? -34.482 34.894 -58.577 1.00 50.21 ? 205 THR H CA 1 ATOM 5682 C C . THR C 3 213 ? -35.674 35.858 -58.750 1.00 53.45 ? 205 THR H C 1 ATOM 5683 O O . THR C 3 213 ? -35.915 36.744 -57.930 1.00 50.13 ? 205 THR H O 1 ATOM 5684 C CB . THR C 3 213 ? -34.807 33.773 -57.536 1.00 51.25 ? 205 THR H CB 1 ATOM 5685 O OG1 . THR C 3 213 ? -33.686 32.883 -57.419 1.00 55.42 ? 205 THR H OG1 1 ATOM 5686 C CG2 . THR C 3 213 ? -36.055 32.938 -57.922 1.00 45.74 ? 205 THR H CG2 1 ATOM 5687 N N . LYS C 3 214 ? -36.409 35.729 -59.839 1.00 56.19 ? 206 LYS H N 1 ATOM 5688 C CA . LYS C 3 214 ? -37.660 36.483 -59.951 1.00 61.29 ? 206 LYS H CA 1 ATOM 5689 C C . LYS C 3 214 ? -38.695 35.577 -60.614 1.00 58.97 ? 206 LYS H C 1 ATOM 5690 O O . LYS C 3 214 ? -38.523 35.145 -61.753 1.00 67.68 ? 206 LYS H O 1 ATOM 5691 C CB . LYS C 3 214 ? -37.454 37.819 -60.683 1.00 58.11 ? 206 LYS H CB 1 ATOM 5692 C CG . LYS C 3 214 ? -38.726 38.657 -60.892 1.00 75.35 ? 206 LYS H CG 1 ATOM 5693 C CD . LYS C 3 214 ? -39.551 38.833 -59.610 1.00 76.00 ? 206 LYS H CD 1 ATOM 5694 C CE . LYS C 3 214 ? -40.833 39.665 -59.837 1.00 90.59 ? 206 LYS H CE 1 ATOM 5695 N NZ . LYS C 3 214 ? -41.791 39.106 -60.855 1.00 89.06 ? 206 LYS H NZ 1 ATOM 5696 N N . VAL C 3 215 ? -39.733 35.238 -59.864 1.00 50.71 ? 207 VAL H N 1 ATOM 5697 C CA . VAL C 3 215 ? -40.750 34.324 -60.348 1.00 50.19 ? 207 VAL H CA 1 ATOM 5698 C C . VAL C 3 215 ? -42.159 34.939 -60.300 1.00 62.03 ? 207 VAL H C 1 ATOM 5699 O O . VAL C 3 215 ? -42.533 35.590 -59.307 1.00 52.19 ? 207 VAL H O 1 ATOM 5700 C CB . VAL C 3 215 ? -40.784 33.045 -59.510 1.00 48.58 ? 207 VAL H CB 1 ATOM 5701 C CG1 . VAL C 3 215 ? -41.897 32.142 -60.023 1.00 53.93 ? 207 VAL H CG1 1 ATOM 5702 C CG2 . VAL C 3 215 ? -39.448 32.326 -59.596 1.00 66.17 ? 207 VAL H CG2 1 ATOM 5703 N N . ASP C 3 216 ? -42.939 34.729 -61.365 1.00 53.78 ? 208 ASP H N 1 ATOM 5704 C CA . ASP C 3 216 ? -44.379 35.013 -61.317 1.00 49.92 ? 208 ASP H CA 1 ATOM 5705 C C . ASP C 3 216 ? -45.123 33.687 -61.191 1.00 56.11 ? 208 ASP H C 1 ATOM 5706 O O . ASP C 3 216 ? -44.673 32.658 -61.706 1.00 63.82 ? 208 ASP H O 1 ATOM 5707 C CB . ASP C 3 216 ? -44.825 35.780 -62.550 1.00 50.85 ? 208 ASP H CB 1 ATOM 5708 C CG . ASP C 3 216 ? -44.048 37.083 -62.737 1.00 55.14 ? 208 ASP H CG 1 ATOM 5709 O OD1 . ASP C 3 216 ? -43.959 37.874 -61.773 1.00 58.99 ? 208 ASP H OD1 1 ATOM 5710 O OD2 . ASP C 3 216 ? -43.521 37.313 -63.851 1.00 57.27 ? 208 ASP H OD2 1 ATOM 5711 N N . LYS C 3 217 ? -46.237 33.685 -60.477 1.00 49.27 ? 209 LYS H N 1 ATOM 5712 C CA . LYS C 3 217 ? -46.983 32.444 -60.316 1.00 47.28 ? 209 LYS H CA 1 ATOM 5713 C C . LYS C 3 217 ? -48.465 32.732 -60.315 1.00 63.80 ? 209 LYS H C 1 ATOM 5714 O O . LYS C 3 217 ? -48.961 33.495 -59.488 1.00 51.49 ? 209 LYS H O 1 ATOM 5715 C CB . LYS C 3 217 ? -46.579 31.720 -59.036 1.00 50.36 ? 209 LYS H CB 1 ATOM 5716 C CG . LYS C 3 217 ? -47.316 30.413 -58.767 1.00 54.76 ? 209 LYS H CG 1 ATOM 5717 C CD . LYS C 3 217 ? -47.050 29.356 -59.842 1.00 58.30 ? 209 LYS H CD 1 ATOM 5718 C CE . LYS C 3 217 ? -45.570 29.211 -60.174 1.00 63.69 ? 209 LYS H CE 1 ATOM 5719 N NZ . LYS C 3 217 ? -45.304 28.134 -61.181 1.00 73.26 ? 209 LYS H NZ 1 ATOM 5720 N N . ARG C 3 218 ? -49.171 32.110 -61.251 1.00 62.29 ? 210 ARG H N 1 ATOM 5721 C CA . ARG C 3 218 ? -50.588 32.359 -61.396 1.00 62.22 ? 210 ARG H CA 1 ATOM 5722 C C . ARG C 3 218 ? -51.349 31.480 -60.419 1.00 51.03 ? 210 ARG H C 1 ATOM 5723 O O . ARG C 3 218 ? -51.059 30.292 -60.249 1.00 50.49 ? 210 ARG H O 1 ATOM 5724 C CB . ARG C 3 218 ? -51.024 32.102 -62.838 1.00 70.72 ? 210 ARG H CB 1 ATOM 5725 C CG . ARG C 3 218 ? -52.489 32.409 -63.089 1.00 84.90 ? 210 ARG H CG 1 ATOM 5726 C CD . ARG C 3 218 ? -52.904 32.146 -64.543 1.00 93.81 ? 210 ARG H CD 1 ATOM 5727 N NE . ARG C 3 218 ? -54.297 32.533 -64.763 1.00 84.45 ? 210 ARG H NE 1 ATOM 5728 C CZ . ARG C 3 218 ? -54.804 32.907 -65.933 1.00 88.41 ? 210 ARG H CZ 1 ATOM 5729 N NH1 . ARG C 3 218 ? -54.042 32.941 -67.023 1.00 78.68 ? 210 ARG H NH1 1 ATOM 5730 N NH2 . ARG C 3 218 ? -56.082 33.247 -66.011 1.00 90.15 ? 210 ARG H NH2 1 ATOM 5731 N N . VAL C 3 219 ? -52.316 32.075 -59.743 1.00 54.47 ? 211 VAL H N 1 ATOM 5732 C CA . VAL C 3 219 ? -53.071 31.306 -58.770 1.00 65.84 ? 211 VAL H CA 1 ATOM 5733 C C . VAL C 3 219 ? -54.530 31.244 -59.212 1.00 70.22 ? 211 VAL H C 1 ATOM 5734 O O . VAL C 3 219 ? -55.236 32.266 -59.247 1.00 61.85 ? 211 VAL H O 1 ATOM 5735 C CB . VAL C 3 219 ? -52.885 31.844 -57.330 1.00 63.02 ? 211 VAL H CB 1 ATOM 5736 C CG1 . VAL C 3 219 ? -53.073 33.328 -57.300 1.00 66.86 ? 211 VAL H CG1 1 ATOM 5737 C CG2 . VAL C 3 219 ? -53.832 31.139 -56.349 1.00 59.98 ? 211 VAL H CG2 1 ATOM 5738 N N . GLU C 3 220 ? -54.935 30.031 -59.589 1.00 80.57 ? 212 GLU H N 1 ATOM 5739 C CA . GLU C 3 220 ? -56.257 29.736 -60.146 1.00 83.09 ? 212 GLU H CA 1 ATOM 5740 C C . GLU C 3 220 ? -57.073 28.858 -59.209 1.00 77.93 ? 212 GLU H C 1 ATOM 5741 O O . GLU C 3 220 ? -56.509 28.082 -58.426 1.00 66.98 ? 212 GLU H O 1 ATOM 5742 C CB . GLU C 3 220 ? -56.112 28.993 -61.473 1.00 82.16 ? 212 GLU H CB 1 ATOM 5743 C CG . GLU C 3 220 ? -55.859 29.863 -62.668 1.00 88.45 ? 212 GLU H CG 1 ATOM 5744 C CD . GLU C 3 220 ? -55.410 29.041 -63.845 1.00 103.90 ? 212 GLU H CD 1 ATOM 5745 O OE1 . GLU C 3 220 ? -56.159 28.125 -64.243 1.00 108.16 ? 212 GLU H OE1 1 ATOM 5746 O OE2 . GLU C 3 220 ? -54.299 29.288 -64.358 1.00 111.06 ? 212 GLU H OE2 1 ATOM 5747 N N . PRO C 3 221 ? -58.407 28.957 -59.309 1.00 78.55 ? 213 PRO H N 1 ATOM 5748 C CA . PRO C 3 221 ? -59.333 28.152 -58.505 1.00 78.86 ? 213 PRO H CA 1 ATOM 5749 C C . PRO C 3 221 ? -59.197 26.649 -58.762 1.00 77.94 ? 213 PRO H C 1 ATOM 5750 O O . PRO C 3 221 ? -59.224 25.868 -57.803 1.00 84.19 ? 213 PRO H O 1 ATOM 5751 C CB . PRO C 3 221 ? -60.702 28.654 -58.963 1.00 78.71 ? 213 PRO H CB 1 ATOM 5752 C CG . PRO C 3 221 ? -60.449 30.043 -59.464 1.00 73.52 ? 213 PRO H CG 1 ATOM 5753 C CD . PRO C 3 221 ? -59.110 29.979 -60.106 1.00 75.82 ? 213 PRO H CD 1 ATOM 5754 N N . SER D 4 2 ? -27.343 39.734 -17.277 1.00 58.69 ? 2 SER L N 1 ATOM 5755 C CA . SER D 4 2 ? -27.304 39.760 -15.804 1.00 51.80 ? 2 SER L CA 1 ATOM 5756 C C . SER D 4 2 ? -26.344 40.822 -15.248 1.00 57.51 ? 2 SER L C 1 ATOM 5757 O O . SER D 4 2 ? -26.262 41.932 -15.784 1.00 64.55 ? 2 SER L O 1 ATOM 5758 C CB . SER D 4 2 ? -27.041 38.371 -15.194 1.00 73.36 ? 2 SER L CB 1 ATOM 5759 O OG . SER D 4 2 ? -25.922 37.715 -15.784 1.00 82.95 ? 2 SER L OG 1 ATOM 5760 N N . ALA D 4 3 ? -25.631 40.483 -14.180 1.00 60.03 ? 3 ALA L N 1 ATOM 5761 C CA . ALA D 4 3 ? -25.052 41.466 -13.278 1.00 47.55 ? 3 ALA L CA 1 ATOM 5762 C C . ALA D 4 3 ? -26.171 42.284 -12.644 1.00 46.43 ? 3 ALA L C 1 ATOM 5763 O O . ALA D 4 3 ? -26.279 42.299 -11.434 1.00 51.80 ? 3 ALA L O 1 ATOM 5764 C CB . ALA D 4 3 ? -24.020 42.357 -13.968 1.00 45.57 ? 3 ALA L CB 1 ATOM 5765 N N . LEU D 4 4 ? -27.012 42.966 -13.437 1.00 38.38 ? 4 LEU L N 1 ATOM 5766 C CA . LEU D 4 4 ? -28.222 43.583 -12.858 1.00 33.37 ? 4 LEU L CA 1 ATOM 5767 C C . LEU D 4 4 ? -29.435 42.670 -13.066 1.00 37.76 ? 4 LEU L C 1 ATOM 5768 O O . LEU D 4 4 ? -29.556 41.994 -14.103 1.00 35.33 ? 4 LEU L O 1 ATOM 5769 C CB . LEU D 4 4 ? -28.492 44.982 -13.445 1.00 34.27 ? 4 LEU L CB 1 ATOM 5770 C CG . LEU D 4 4 ? -27.272 45.889 -13.564 1.00 30.28 ? 4 LEU L CG 1 ATOM 5771 C CD1 . LEU D 4 4 ? -27.647 47.280 -14.112 1.00 25.21 ? 4 LEU L CD1 1 ATOM 5772 C CD2 . LEU D 4 4 ? -26.594 46.022 -12.211 1.00 37.87 ? 4 LEU L CD2 1 ATOM 5773 N N . THR D 4 5 ? -30.331 42.623 -12.073 1.00 33.03 ? 5 THR L N 1 ATOM 5774 C CA . THR D 4 5 ? -31.440 41.670 -12.102 1.00 34.10 ? 5 THR L CA 1 ATOM 5775 C C . THR D 4 5 ? -32.734 42.471 -12.050 1.00 31.87 ? 5 THR L C 1 ATOM 5776 O O . THR D 4 5 ? -32.897 43.352 -11.209 1.00 36.10 ? 5 THR L O 1 ATOM 5777 C CB . THR D 4 5 ? -31.366 40.672 -10.888 1.00 40.48 ? 5 THR L CB 1 ATOM 5778 O OG1 . THR D 4 5 ? -30.206 39.829 -11.014 1.00 43.53 ? 5 THR L OG1 1 ATOM 5779 C CG2 . THR D 4 5 ? -32.596 39.798 -10.846 1.00 39.57 ? 5 THR L CG2 1 ATOM 5780 N N . GLN D 4 6 ? -33.618 42.186 -12.992 1.00 31.51 ? 6 GLN L N 1 ATOM 5781 C CA . GLN D 4 6 ? -34.914 42.838 -13.118 1.00 28.01 ? 6 GLN L CA 1 ATOM 5782 C C . GLN D 4 6 ? -35.987 41.771 -13.201 1.00 33.92 ? 6 GLN L C 1 ATOM 5783 O O . GLN D 4 6 ? -35.730 40.670 -13.674 1.00 35.71 ? 6 GLN L O 1 ATOM 5784 C CB . GLN D 4 6 ? -34.978 43.638 -14.429 1.00 30.79 ? 6 GLN L CB 1 ATOM 5785 C CG . GLN D 4 6 ? -34.030 44.791 -14.531 1.00 29.80 ? 6 GLN L CG 1 ATOM 5786 C CD . GLN D 4 6 ? -34.131 45.443 -15.926 1.00 29.43 ? 6 GLN L CD 1 ATOM 5787 O OE1 . GLN D 4 6 ? -33.164 45.453 -16.717 1.00 28.72 ? 6 GLN L OE1 1 ATOM 5788 N NE2 . GLN D 4 6 ? -35.302 45.984 -16.225 1.00 24.49 ? 6 GLN L NE2 1 ATOM 5789 N N . PRO D 4 7 ? -37.233 42.117 -12.822 1.00 31.66 ? 7 PRO L N 1 ATOM 5790 C CA . PRO D 4 7 ? -38.324 41.168 -13.027 1.00 37.52 ? 7 PRO L CA 1 ATOM 5791 C C . PRO D 4 7 ? -38.548 41.046 -14.528 1.00 35.44 ? 7 PRO L C 1 ATOM 5792 O O . PRO D 4 7 ? -38.471 42.041 -15.234 1.00 32.07 ? 7 PRO L O 1 ATOM 5793 C CB . PRO D 4 7 ? -39.515 41.875 -12.369 1.00 39.09 ? 7 PRO L CB 1 ATOM 5794 C CG . PRO D 4 7 ? -39.133 43.329 -12.402 1.00 39.47 ? 7 PRO L CG 1 ATOM 5795 C CD . PRO D 4 7 ? -37.688 43.371 -12.221 1.00 32.99 ? 7 PRO L CD 1 ATOM 5796 N N . PRO D 4 8 ? -38.800 39.844 -15.024 1.00 34.10 ? 8 PRO L N 1 ATOM 5797 C CA . PRO D 4 8 ? -39.026 39.728 -16.464 1.00 37.96 ? 8 PRO L CA 1 ATOM 5798 C C . PRO D 4 8 ? -40.284 40.474 -16.946 1.00 39.45 ? 8 PRO L C 1 ATOM 5799 O O . PRO D 4 8 ? -40.326 40.820 -18.132 1.00 32.61 ? 8 PRO L O 1 ATOM 5800 C CB . PRO D 4 8 ? -39.204 38.212 -16.675 1.00 42.35 ? 8 PRO L CB 1 ATOM 5801 C CG . PRO D 4 8 ? -38.605 37.577 -15.477 1.00 41.75 ? 8 PRO L CG 1 ATOM 5802 C CD . PRO D 4 8 ? -38.792 38.536 -14.342 1.00 41.90 ? 8 PRO L CD 1 ATOM 5803 N N . ALA D 4 9 ? -41.265 40.726 -16.072 1.00 33.27 ? 9 ALA L N 1 ATOM 5804 C CA . ALA D 4 9 ? -42.557 41.280 -16.496 1.00 33.76 ? 9 ALA L CA 1 ATOM 5805 C C . ALA D 4 9 ? -43.155 42.185 -15.421 1.00 36.00 ? 9 ALA L C 1 ATOM 5806 O O . ALA D 4 9 ? -42.997 41.910 -14.221 1.00 36.25 ? 9 ALA L O 1 ATOM 5807 C CB . ALA D 4 9 ? -43.540 40.154 -16.853 1.00 36.14 ? 9 ALA L CB 1 ATOM 5808 N N . VAL D 4 10 ? -43.797 43.270 -15.855 1.00 31.98 ? 11 VAL L N 1 ATOM 5809 C CA . VAL D 4 10 ? -44.625 44.085 -14.996 1.00 33.76 ? 11 VAL L CA 1 ATOM 5810 C C . VAL D 4 10 ? -45.864 44.482 -15.795 1.00 37.52 ? 11 VAL L C 1 ATOM 5811 O O . VAL D 4 10 ? -45.836 44.511 -17.037 1.00 30.46 ? 11 VAL L O 1 ATOM 5812 C CB . VAL D 4 10 ? -43.938 45.355 -14.477 1.00 30.19 ? 11 VAL L CB 1 ATOM 5813 C CG1 . VAL D 4 10 ? -42.863 45.046 -13.491 1.00 37.59 ? 11 VAL L CG1 1 ATOM 5814 C CG2 . VAL D 4 10 ? -43.416 46.267 -15.671 1.00 35.12 ? 11 VAL L CG2 1 ATOM 5815 N N . SER D 4 11 ? -46.976 44.754 -15.111 1.00 28.88 ? 12 SER L N 1 ATOM 5816 C CA . SER D 4 11 ? -48.158 45.196 -15.837 1.00 32.85 ? 12 SER L CA 1 ATOM 5817 C C . SER D 4 11 ? -48.946 46.225 -15.037 1.00 30.89 ? 12 SER L C 1 ATOM 5818 O O . SER D 4 11 ? -48.748 46.364 -13.816 1.00 31.50 ? 12 SER L O 1 ATOM 5819 C CB . SER D 4 11 ? -49.010 43.988 -16.237 1.00 31.73 ? 12 SER L CB 1 ATOM 5820 O OG . SER D 4 11 ? -49.491 43.357 -15.064 1.00 38.53 ? 12 SER L OG 1 ATOM 5821 N N . GLY D 4 12 ? -49.807 46.960 -15.726 1.00 25.65 ? 13 GLY L N 1 ATOM 5822 C CA . GLY D 4 12 ? -50.692 47.912 -15.079 1.00 25.94 ? 13 GLY L CA 1 ATOM 5823 C C . GLY D 4 12 ? -51.757 48.376 -16.015 1.00 32.02 ? 13 GLY L C 1 ATOM 5824 O O . GLY D 4 12 ? -51.695 48.114 -17.226 1.00 29.06 ? 13 GLY L O 1 ATOM 5825 N N . THR D 4 13 ? -52.743 49.091 -15.473 1.00 30.13 ? 14 THR L N 1 ATOM 5826 C CA . THR D 4 13 ? -53.756 49.668 -16.289 1.00 25.21 ? 14 THR L CA 1 ATOM 5827 C C . THR D 4 13 ? -53.452 51.080 -16.580 1.00 23.63 ? 14 THR L C 1 ATOM 5828 O O . THR D 4 13 ? -52.725 51.704 -15.849 1.00 31.74 ? 14 THR L O 1 ATOM 5829 C CB . THR D 4 13 ? -55.172 49.616 -15.547 1.00 35.05 ? 14 THR L CB 1 ATOM 5830 O OG1 . THR D 4 13 ? -55.059 50.229 -14.267 1.00 34.70 ? 14 THR L OG1 1 ATOM 5831 C CG2 . THR D 4 13 ? -55.576 48.212 -15.338 1.00 31.72 ? 14 THR L CG2 1 ATOM 5832 N N . PRO D 4 14 ? -54.074 51.619 -17.639 1.00 25.64 ? 15 PRO L N 1 ATOM 5833 C CA . PRO D 4 14 ? -53.884 53.028 -17.995 1.00 32.18 ? 15 PRO L CA 1 ATOM 5834 C C . PRO D 4 14 ? -54.184 53.900 -16.790 1.00 36.30 ? 15 PRO L C 1 ATOM 5835 O O . PRO D 4 14 ? -55.191 53.641 -16.097 1.00 35.18 ? 15 PRO L O 1 ATOM 5836 C CB . PRO D 4 14 ? -54.877 53.234 -19.142 1.00 35.58 ? 15 PRO L CB 1 ATOM 5837 C CG . PRO D 4 14 ? -54.980 51.888 -19.781 1.00 33.04 ? 15 PRO L CG 1 ATOM 5838 C CD . PRO D 4 14 ? -54.924 50.922 -18.620 1.00 30.20 ? 15 PRO L CD 1 ATOM 5839 N N . GLY D 4 15 ? -53.257 54.806 -16.468 1.00 31.98 ? 16 GLY L N 1 ATOM 5840 C CA . GLY D 4 15 ? -53.300 55.613 -15.245 1.00 35.68 ? 16 GLY L CA 1 ATOM 5841 C C . GLY D 4 15 ? -52.749 55.025 -13.948 1.00 35.43 ? 16 GLY L C 1 ATOM 5842 O O . GLY D 4 15 ? -52.557 55.752 -12.973 1.00 45.09 ? 16 GLY L O 1 ATOM 5843 N N . GLN D 4 16 ? -52.511 53.723 -13.885 1.00 37.48 ? 17 GLN L N 1 ATOM 5844 C CA . GLN D 4 16 ? -51.915 53.132 -12.678 1.00 32.44 ? 17 GLN L CA 1 ATOM 5845 C C . GLN D 4 16 ? -50.456 53.587 -12.488 1.00 47.72 ? 17 GLN L C 1 ATOM 5846 O O . GLN D 4 16 ? -49.803 54.013 -13.445 1.00 37.54 ? 17 GLN L O 1 ATOM 5847 C CB . GLN D 4 16 ? -51.981 51.600 -12.750 1.00 40.78 ? 17 GLN L CB 1 ATOM 5848 C CG . GLN D 4 16 ? -52.360 50.908 -11.431 1.00 41.54 ? 17 GLN L CG 1 ATOM 5849 C CD . GLN D 4 16 ? -52.469 49.383 -11.539 1.00 43.36 ? 17 GLN L CD 1 ATOM 5850 O OE1 . GLN D 4 16 ? -51.967 48.822 -12.471 1.00 42.86 ? 17 GLN L OE1 1 ATOM 5851 N NE2 . GLN D 4 16 ? -53.158 48.720 -10.561 1.00 33.75 ? 17 GLN L NE2 1 ATOM 5852 N N . ARG D 4 17 ? -49.932 53.497 -11.271 1.00 36.55 ? 18 ARG L N 1 ATOM 5853 C CA . ARG D 4 17 ? -48.493 53.660 -11.070 1.00 44.71 ? 18 ARG L CA 1 ATOM 5854 C C . ARG D 4 17 ? -47.785 52.304 -11.143 1.00 42.74 ? 18 ARG L C 1 ATOM 5855 O O . ARG D 4 17 ? -48.208 51.351 -10.483 1.00 44.28 ? 18 ARG L O 1 ATOM 5856 C CB . ARG D 4 17 ? -48.192 54.313 -9.724 1.00 47.63 ? 18 ARG L CB 1 ATOM 5857 C CG . ARG D 4 17 ? -46.687 54.420 -9.393 1.00 42.56 ? 18 ARG L CG 1 ATOM 5858 C CD . ARG D 4 17 ? -46.475 55.530 -8.363 1.00 56.10 ? 18 ARG L CD 1 ATOM 5859 N NE . ARG D 4 17 ? -45.079 55.870 -8.084 1.00 46.89 ? 18 ARG L NE 1 ATOM 5860 C CZ . ARG D 4 17 ? -44.285 55.146 -7.297 1.00 44.28 ? 18 ARG L CZ 1 ATOM 5861 N NH1 . ARG D 4 17 ? -44.726 54.021 -6.743 1.00 47.05 ? 18 ARG L NH1 1 ATOM 5862 N NH2 . ARG D 4 17 ? -43.030 55.535 -7.087 1.00 54.69 ? 18 ARG L NH2 1 ATOM 5863 N N . VAL D 4 18 ? -46.733 52.183 -11.959 1.00 33.14 ? 19 VAL L N 1 ATOM 5864 C CA . VAL D 4 18 ? -45.992 50.912 -11.988 1.00 29.94 ? 19 VAL L CA 1 ATOM 5865 C C . VAL D 4 18 ? -44.535 51.140 -11.670 1.00 35.50 ? 19 VAL L C 1 ATOM 5866 O O . VAL D 4 18 ? -43.964 52.191 -12.002 1.00 34.61 ? 19 VAL L O 1 ATOM 5867 C CB . VAL D 4 18 ? -46.050 50.196 -13.346 1.00 36.48 ? 19 VAL L CB 1 ATOM 5868 C CG1 . VAL D 4 18 ? -47.498 49.904 -13.746 1.00 38.52 ? 19 VAL L CG1 1 ATOM 5869 C CG2 . VAL D 4 18 ? -45.406 51.033 -14.369 1.00 46.64 ? 19 VAL L CG2 1 ATOM 5870 N N . THR D 4 19 ? -43.931 50.168 -11.012 1.00 29.62 ? 20 THR L N 1 ATOM 5871 C CA . THR D 4 19 ? -42.528 50.286 -10.660 1.00 28.92 ? 20 THR L CA 1 ATOM 5872 C C . THR D 4 19 ? -41.785 49.090 -11.191 1.00 29.67 ? 20 THR L C 1 ATOM 5873 O O . THR D 4 19 ? -42.349 48.021 -11.301 1.00 31.42 ? 20 THR L O 1 ATOM 5874 C CB . THR D 4 19 ? -42.277 50.347 -9.142 1.00 38.00 ? 20 THR L CB 1 ATOM 5875 O OG1 . THR D 4 19 ? -42.723 49.122 -8.547 1.00 41.38 ? 20 THR L OG1 1 ATOM 5876 C CG2 . THR D 4 19 ? -43.000 51.526 -8.561 1.00 38.55 ? 20 THR L CG2 1 ATOM 5877 N N . ILE D 4 20 ? -40.519 49.309 -11.561 1.00 31.48 ? 21 ILE L N 1 ATOM 5878 C CA . ILE D 4 20 ? -39.643 48.241 -12.058 1.00 25.88 ? 21 ILE L CA 1 ATOM 5879 C C . ILE D 4 20 ? -38.341 48.282 -11.283 1.00 26.28 ? 21 ILE L C 1 ATOM 5880 O O . ILE D 4 20 ? -37.660 49.307 -11.262 1.00 30.09 ? 21 ILE L O 1 ATOM 5881 C CB . ILE D 4 20 ? -39.305 48.480 -13.578 1.00 25.53 ? 21 ILE L CB 1 ATOM 5882 C CG1 . ILE D 4 20 ? -40.585 48.355 -14.405 1.00 28.34 ? 21 ILE L CG1 1 ATOM 5883 C CG2 . ILE D 4 20 ? -38.266 47.466 -14.026 1.00 24.24 ? 21 ILE L CG2 1 ATOM 5884 C CD1 . ILE D 4 20 ? -40.454 48.702 -15.959 1.00 26.26 ? 21 ILE L CD1 1 ATOM 5885 N N . SER D 4 21 ? -37.995 47.174 -10.655 1.00 34.81 ? 22 SER L N 1 ATOM 5886 C CA . SER D 4 21 ? -36.823 47.137 -9.783 1.00 33.69 ? 22 SER L CA 1 ATOM 5887 C C . SER D 4 21 ? -35.621 46.644 -10.549 1.00 32.18 ? 22 SER L C 1 ATOM 5888 O O . SER D 4 21 ? -35.751 45.980 -11.588 1.00 36.05 ? 22 SER L O 1 ATOM 5889 C CB . SER D 4 21 ? -37.050 46.181 -8.601 1.00 32.13 ? 22 SER L CB 1 ATOM 5890 O OG . SER D 4 21 ? -37.319 44.851 -9.057 1.00 36.57 ? 22 SER L OG 1 ATOM 5891 N N . CYS D 4 22 ? -34.455 46.937 -9.993 1.00 31.20 ? 23 CYS L N 1 ATOM 5892 C CA . CYS D 4 22 ? -33.173 46.568 -10.563 1.00 31.95 ? 23 CYS L CA 1 ATOM 5893 C C . CYS D 4 22 ? -32.195 46.253 -9.419 1.00 36.36 ? 23 CYS L C 1 ATOM 5894 O O . CYS D 4 22 ? -31.730 47.178 -8.758 1.00 41.91 ? 23 CYS L O 1 ATOM 5895 C CB . CYS D 4 22 ? -32.631 47.784 -11.337 1.00 33.44 ? 23 CYS L CB 1 ATOM 5896 S SG . CYS D 4 22 ? -30.999 47.537 -12.211 1.00 38.64 ? 23 CYS L SG 1 ATOM 5897 N N . SER D 4 23 ? -31.856 44.982 -9.232 1.00 37.37 ? 24 SER L N 1 ATOM 5898 C CA . SER D 4 23 ? -30.862 44.606 -8.202 1.00 40.84 ? 24 SER L CA 1 ATOM 5899 C C . SER D 4 23 ? -29.468 44.426 -8.777 1.00 38.87 ? 24 SER L C 1 ATOM 5900 O O . SER D 4 23 ? -29.289 43.691 -9.762 1.00 35.35 ? 24 SER L O 1 ATOM 5901 C CB . SER D 4 23 ? -31.277 43.306 -7.507 1.00 44.31 ? 24 SER L CB 1 ATOM 5902 O OG . SER D 4 23 ? -32.554 43.457 -6.919 1.00 63.06 ? 24 SER L OG 1 ATOM 5903 N N . GLY D 4 24 ? -28.493 45.084 -8.145 1.00 37.58 ? 25 GLY L N 1 ATOM 5904 C CA . GLY D 4 24 ? -27.096 44.966 -8.501 1.00 42.38 ? 25 GLY L CA 1 ATOM 5905 C C . GLY D 4 24 ? -26.214 44.556 -7.329 1.00 57.02 ? 25 GLY L C 1 ATOM 5906 O O . GLY D 4 24 ? -26.613 43.778 -6.460 1.00 52.37 ? 25 GLY L O 1 ATOM 5907 N N . SER D 4 25 ? -25.004 45.092 -7.309 1.00 47.30 ? 26 SER L N 1 ATOM 5908 C CA . SER D 4 25 ? -23.978 44.681 -6.351 1.00 46.87 ? 26 SER L CA 1 ATOM 5909 C C . SER D 4 25 ? -23.184 45.924 -6.021 1.00 40.04 ? 26 SER L C 1 ATOM 5910 O O . SER D 4 25 ? -23.481 46.996 -6.535 1.00 37.15 ? 26 SER L O 1 ATOM 5911 C CB . SER D 4 25 ? -23.066 43.608 -6.937 1.00 43.23 ? 26 SER L CB 1 ATOM 5912 O OG . SER D 4 25 ? -21.936 44.191 -7.577 1.00 55.12 ? 26 SER L OG 1 ATOM 5913 N N . ASP D 4 26 ? -22.197 45.795 -5.130 1.00 47.82 ? 27 ASP L N 1 ATOM 5914 C CA . ASP D 4 26 ? -21.368 46.937 -4.760 1.00 48.03 ? 27 ASP L CA 1 ATOM 5915 C C . ASP D 4 26 ? -20.545 47.456 -5.930 1.00 41.38 ? 27 ASP L C 1 ATOM 5916 O O . ASP D 4 26 ? -20.289 48.652 -6.029 1.00 47.51 ? 27 ASP L O 1 ATOM 5917 C CB . ASP D 4 26 ? -20.420 46.542 -3.611 1.00 53.93 ? 27 ASP L CB 1 ATOM 5918 C CG . ASP D 4 26 ? -21.173 46.102 -2.364 1.00 70.13 ? 27 ASP L CG 1 ATOM 5919 O OD1 . ASP D 4 26 ? -22.107 46.832 -1.937 1.00 50.93 ? 27 ASP L OD1 1 ATOM 5920 O OD2 . ASP D 4 26 ? -20.845 45.018 -1.831 1.00 80.44 ? 27 ASP L OD2 1 ATOM 5921 N N . SER D 4 27 A -20.138 46.561 -6.825 1.00 39.16 ? 27 SER L N 1 ATOM 5922 C CA . SER D 4 27 A -19.234 46.971 -7.917 1.00 37.03 ? 27 SER L CA 1 ATOM 5923 C C . SER D 4 27 A -19.933 47.742 -9.039 1.00 38.58 ? 27 SER L C 1 ATOM 5924 O O . SER D 4 27 A -19.262 48.320 -9.885 1.00 34.04 ? 27 SER L O 1 ATOM 5925 C CB . SER D 4 27 A -18.534 45.761 -8.537 1.00 37.65 ? 27 SER L CB 1 ATOM 5926 O OG . SER D 4 27 A -19.501 44.851 -9.029 1.00 39.99 ? 27 SER L OG 1 ATOM 5927 N N . ASN D 4 28 B -21.260 47.713 -9.058 1.00 32.63 ? 27 ASN L N 1 ATOM 5928 C CA . ASN D 4 28 B -22.018 48.528 -10.014 1.00 39.08 ? 27 ASN L CA 1 ATOM 5929 C C . ASN D 4 28 B -22.957 49.542 -9.332 1.00 33.18 ? 27 ASN L C 1 ATOM 5930 O O . ASN D 4 28 B -22.540 50.662 -9.067 1.00 42.04 ? 27 ASN L O 1 ATOM 5931 C CB . ASN D 4 28 B -22.740 47.662 -11.069 1.00 28.82 ? 27 ASN L CB 1 ATOM 5932 C CG . ASN D 4 28 B -23.469 46.464 -10.463 1.00 28.38 ? 27 ASN L CG 1 ATOM 5933 O OD1 . ASN D 4 28 B -24.444 46.648 -9.716 1.00 33.43 ? 27 ASN L OD1 1 ATOM 5934 N ND2 . ASN D 4 28 B -23.060 45.258 -10.823 1.00 31.07 ? 27 ASN L ND2 1 ATOM 5935 N N . ILE D 4 29 ? -24.203 49.153 -9.090 1.00 32.08 ? 28 ILE L N 1 ATOM 5936 C CA . ILE D 4 29 ? -25.195 50.092 -8.557 1.00 38.35 ? 28 ILE L CA 1 ATOM 5937 C C . ILE D 4 29 ? -24.680 50.714 -7.255 1.00 52.19 ? 28 ILE L C 1 ATOM 5938 O O . ILE D 4 29 ? -24.776 51.926 -7.057 1.00 50.10 ? 28 ILE L O 1 ATOM 5939 C CB . ILE D 4 29 ? -26.546 49.416 -8.343 1.00 43.25 ? 28 ILE L CB 1 ATOM 5940 C CG1 . ILE D 4 29 ? -27.081 48.900 -9.685 1.00 44.34 ? 28 ILE L CG1 1 ATOM 5941 C CG2 . ILE D 4 29 ? -27.559 50.382 -7.682 1.00 42.99 ? 28 ILE L CG2 1 ATOM 5942 C CD1 . ILE D 4 29 ? -28.546 48.648 -9.677 1.00 41.13 ? 28 ILE L CD1 1 ATOM 5943 N N . GLY D 4 30 ? -24.055 49.883 -6.426 1.00 47.20 ? 29 GLY L N 1 ATOM 5944 C CA . GLY D 4 30 ? -23.477 50.341 -5.165 1.00 55.80 ? 29 GLY L CA 1 ATOM 5945 C C . GLY D 4 30 ? -22.663 51.615 -5.320 1.00 55.48 ? 29 GLY L C 1 ATOM 5946 O O . GLY D 4 30 ? -22.915 52.631 -4.653 1.00 61.20 ? 29 GLY L O 1 ATOM 5947 N N . ARG D 4 31 ? -21.712 51.581 -6.245 1.00 44.79 ? 30 ARG L N 1 ATOM 5948 C CA . ARG D 4 31 ? -20.743 52.648 -6.361 1.00 42.85 ? 30 ARG L CA 1 ATOM 5949 C C . ARG D 4 31 ? -20.857 53.450 -7.638 1.00 48.69 ? 30 ARG L C 1 ATOM 5950 O O . ARG D 4 31 ? -20.081 54.392 -7.835 1.00 45.53 ? 30 ARG L O 1 ATOM 5951 C CB . ARG D 4 31 ? -19.334 52.058 -6.232 1.00 50.51 ? 30 ARG L CB 1 ATOM 5952 C CG . ARG D 4 31 ? -19.097 51.402 -4.856 1.00 60.45 ? 30 ARG L CG 1 ATOM 5953 C CD . ARG D 4 31 ? -18.084 50.242 -4.874 1.00 69.86 ? 30 ARG L CD 1 ATOM 5954 N NE . ARG D 4 31 ? -16.722 50.678 -5.146 1.00 88.89 ? 30 ARG L NE 1 ATOM 5955 C CZ . ARG D 4 31 ? -16.180 50.733 -6.359 1.00 83.88 ? 30 ARG L CZ 1 ATOM 5956 N NH1 . ARG D 4 31 ? -16.895 50.375 -7.434 1.00 64.63 ? 30 ARG L NH1 1 ATOM 5957 N NH2 . ARG D 4 31 ? -14.922 51.153 -6.490 1.00 81.61 ? 30 ARG L NH2 1 ATOM 5958 N N . ARG D 4 32 ? -21.804 53.093 -8.518 1.00 36.32 ? 31 ARG L N 1 ATOM 5959 C CA . ARG D 4 32 ? -21.958 53.869 -9.750 1.00 38.01 ? 31 ARG L CA 1 ATOM 5960 C C . ARG D 4 32 ? -23.406 54.277 -10.053 1.00 30.74 ? 31 ARG L C 1 ATOM 5961 O O . ARG D 4 32 ? -24.353 53.676 -9.530 1.00 39.51 ? 31 ARG L O 1 ATOM 5962 C CB . ARG D 4 32 ? -21.421 53.101 -10.974 1.00 34.29 ? 31 ARG L CB 1 ATOM 5963 C CG . ARG D 4 32 ? -19.952 52.762 -10.945 1.00 43.41 ? 31 ARG L CG 1 ATOM 5964 C CD . ARG D 4 32 ? -19.227 53.944 -11.511 1.00 32.52 ? 31 ARG L CD 1 ATOM 5965 N NE . ARG D 4 32 ? -17.802 53.713 -11.586 1.00 38.87 ? 31 ARG L NE 1 ATOM 5966 C CZ . ARG D 4 32 ? -16.968 54.566 -12.155 1.00 44.74 ? 31 ARG L CZ 1 ATOM 5967 N NH1 . ARG D 4 32 ? -17.475 55.669 -12.709 1.00 43.63 ? 31 ARG L NH1 1 ATOM 5968 N NH2 . ARG D 4 32 ? -15.661 54.309 -12.189 1.00 48.01 ? 31 ARG L NH2 1 ATOM 5969 N N . SER D 4 33 ? -23.540 55.252 -10.957 1.00 31.64 ? 32 SER L N 1 ATOM 5970 C CA . SER D 4 33 ? -24.844 55.837 -11.335 1.00 32.74 ? 32 SER L CA 1 ATOM 5971 C C . SER D 4 33 ? -25.628 54.914 -12.261 1.00 38.42 ? 32 SER L C 1 ATOM 5972 O O . SER D 4 33 ? -25.022 54.255 -13.121 1.00 38.82 ? 32 SER L O 1 ATOM 5973 C CB . SER D 4 33 ? -24.634 57.135 -12.088 1.00 35.34 ? 32 SER L CB 1 ATOM 5974 O OG . SER D 4 33 ? -24.164 58.154 -11.222 1.00 56.25 ? 32 SER L OG 1 ATOM 5975 N N . VAL D 4 34 ? -26.951 54.931 -12.130 1.00 32.95 ? 33 VAL L N 1 ATOM 5976 C CA . VAL D 4 34 ? -27.837 54.066 -12.960 1.00 30.12 ? 33 VAL L CA 1 ATOM 5977 C C . VAL D 4 34 ? -28.492 54.804 -14.136 1.00 32.92 ? 33 VAL L C 1 ATOM 5978 O O . VAL D 4 34 ? -28.893 55.954 -13.986 1.00 29.21 ? 33 VAL L O 1 ATOM 5979 C CB . VAL D 4 34 ? -28.842 53.399 -12.056 1.00 29.42 ? 33 VAL L CB 1 ATOM 5980 C CG1 . VAL D 4 34 ? -29.910 52.585 -12.860 1.00 31.30 ? 33 VAL L CG1 1 ATOM 5981 C CG2 . VAL D 4 34 ? -28.087 52.525 -11.043 1.00 29.63 ? 33 VAL L CG2 1 ATOM 5982 N N . ASN D 4 35 ? -28.581 54.155 -15.327 1.00 23.95 ? 34 ASN L N 1 ATOM 5983 C CA . ASN D 4 35 ? -29.283 54.711 -16.477 1.00 25.28 ? 34 ASN L CA 1 ATOM 5984 C C . ASN D 4 35 ? -30.389 53.739 -16.798 1.00 23.16 ? 34 ASN L C 1 ATOM 5985 O O . ASN D 4 35 ? -30.269 52.548 -16.486 1.00 27.06 ? 34 ASN L O 1 ATOM 5986 C CB . ASN D 4 35 ? -28.363 54.813 -17.724 1.00 24.80 ? 34 ASN L CB 1 ATOM 5987 C CG . ASN D 4 35 ? -27.079 55.650 -17.475 1.00 32.60 ? 34 ASN L CG 1 ATOM 5988 O OD1 . ASN D 4 35 ? -27.135 56.822 -17.115 1.00 31.26 ? 34 ASN L OD1 1 ATOM 5989 N ND2 . ASN D 4 35 ? -25.916 55.054 -17.759 1.00 28.45 ? 34 ASN L ND2 1 ATOM 5990 N N . TRP D 4 36 ? -31.497 54.235 -17.328 1.00 25.29 ? 35 TRP L N 1 ATOM 5991 C CA . TRP D 4 36 ? -32.588 53.381 -17.711 1.00 24.16 ? 35 TRP L CA 1 ATOM 5992 C C . TRP D 4 36 ? -32.902 53.634 -19.187 1.00 22.99 ? 35 TRP L C 1 ATOM 5993 O O . TRP D 4 36 ? -32.863 54.771 -19.638 1.00 24.34 ? 35 TRP L O 1 ATOM 5994 C CB . TRP D 4 36 ? -33.830 53.728 -16.914 1.00 23.42 ? 35 TRP L CB 1 ATOM 5995 C CG . TRP D 4 36 ? -33.782 53.279 -15.498 1.00 27.88 ? 35 TRP L CG 1 ATOM 5996 C CD1 . TRP D 4 36 ? -33.334 53.996 -14.411 1.00 27.13 ? 35 TRP L CD1 1 ATOM 5997 C CD2 . TRP D 4 36 ? -34.274 52.035 -14.998 1.00 26.92 ? 35 TRP L CD2 1 ATOM 5998 N NE1 . TRP D 4 36 ? -33.491 53.234 -13.279 1.00 27.74 ? 35 TRP L NE1 1 ATOM 5999 C CE2 . TRP D 4 36 ? -34.093 52.047 -13.596 1.00 27.90 ? 35 TRP L CE2 1 ATOM 6000 C CE3 . TRP D 4 36 ? -34.871 50.924 -15.591 1.00 22.58 ? 35 TRP L CE3 1 ATOM 6001 C CZ2 . TRP D 4 36 ? -34.460 50.966 -12.786 1.00 28.86 ? 35 TRP L CZ2 1 ATOM 6002 C CZ3 . TRP D 4 36 ? -35.251 49.844 -14.785 1.00 27.59 ? 35 TRP L CZ3 1 ATOM 6003 C CH2 . TRP D 4 36 ? -35.019 49.875 -13.370 1.00 27.78 ? 35 TRP L CH2 1 ATOM 6004 N N . TYR D 4 37 ? -33.248 52.575 -19.921 1.00 21.85 ? 36 TYR L N 1 ATOM 6005 C CA . TYR D 4 37 ? -33.574 52.680 -21.332 1.00 22.28 ? 36 TYR L CA 1 ATOM 6006 C C . TYR D 4 37 ? -34.935 52.036 -21.589 1.00 19.35 ? 36 TYR L C 1 ATOM 6007 O O . TYR D 4 37 ? -35.269 51.014 -20.933 1.00 20.58 ? 36 TYR L O 1 ATOM 6008 C CB . TYR D 4 37 ? -32.520 51.918 -22.170 1.00 20.28 ? 36 TYR L CB 1 ATOM 6009 C CG . TYR D 4 37 ? -31.154 52.515 -22.003 1.00 17.42 ? 36 TYR L CG 1 ATOM 6010 C CD1 . TYR D 4 37 ? -30.779 53.630 -22.797 1.00 18.56 ? 36 TYR L CD1 1 ATOM 6011 C CD2 . TYR D 4 37 ? -30.269 52.012 -21.062 1.00 21.93 ? 36 TYR L CD2 1 ATOM 6012 C CE1 . TYR D 4 37 ? -29.499 54.222 -22.636 1.00 20.40 ? 36 TYR L CE1 1 ATOM 6013 C CE2 . TYR D 4 37 ? -29.029 52.583 -20.890 1.00 20.00 ? 36 TYR L CE2 1 ATOM 6014 C CZ . TYR D 4 37 ? -28.671 53.679 -21.641 1.00 18.60 ? 36 TYR L CZ 1 ATOM 6015 O OH . TYR D 4 37 ? -27.413 54.203 -21.427 1.00 20.90 ? 36 TYR L OH 1 ATOM 6016 N N . GLN D 4 38 ? -35.668 52.587 -22.571 1.00 21.00 ? 37 GLN L N 1 ATOM 6017 C CA . GLN D 4 38 ? -36.962 52.052 -23.004 1.00 18.20 ? 37 GLN L CA 1 ATOM 6018 C C . GLN D 4 38 ? -36.769 51.551 -24.440 1.00 22.48 ? 37 GLN L C 1 ATOM 6019 O O . GLN D 4 38 ? -36.115 52.220 -25.221 1.00 24.08 ? 37 GLN L O 1 ATOM 6020 C CB . GLN D 4 38 ? -37.945 53.204 -23.052 1.00 18.38 ? 37 GLN L CB 1 ATOM 6021 C CG . GLN D 4 38 ? -39.361 52.789 -23.507 1.00 22.21 ? 37 GLN L CG 1 ATOM 6022 C CD . GLN D 4 38 ? -40.230 54.008 -23.746 1.00 30.73 ? 37 GLN L CD 1 ATOM 6023 O OE1 . GLN D 4 38 ? -39.862 54.888 -24.528 1.00 29.01 ? 37 GLN L OE1 1 ATOM 6024 N NE2 . GLN D 4 38 ? -41.385 54.100 -23.031 1.00 27.86 ? 37 GLN L NE2 1 ATOM 6025 N N . GLN D 4 39 ? -37.317 50.393 -24.777 1.00 19.40 ? 38 GLN L N 1 ATOM 6026 C CA . GLN D 4 39 ? -37.144 49.875 -26.153 1.00 18.61 ? 38 GLN L CA 1 ATOM 6027 C C . GLN D 4 39 ? -38.445 49.279 -26.668 1.00 21.28 ? 38 GLN L C 1 ATOM 6028 O O . GLN D 4 39 ? -38.988 48.372 -26.051 1.00 23.03 ? 38 GLN L O 1 ATOM 6029 C CB . GLN D 4 39 ? -36.110 48.768 -26.157 1.00 18.42 ? 38 GLN L CB 1 ATOM 6030 C CG . GLN D 4 39 ? -35.680 48.422 -27.626 1.00 19.78 ? 38 GLN L CG 1 ATOM 6031 C CD . GLN D 4 39 ? -34.705 47.266 -27.671 1.00 20.85 ? 38 GLN L CD 1 ATOM 6032 O OE1 . GLN D 4 39 ? -34.583 46.477 -26.725 1.00 21.84 ? 38 GLN L OE1 1 ATOM 6033 N NE2 . GLN D 4 39 ? -33.981 47.144 -28.807 1.00 20.93 ? 38 GLN L NE2 1 ATOM 6034 N N . PHE D 4 40 ? -38.900 49.765 -27.805 1.00 22.23 ? 39 PHE L N 1 ATOM 6035 C CA . PHE D 4 40 ? -40.034 49.160 -28.518 1.00 21.56 ? 39 PHE L CA 1 ATOM 6036 C C . PHE D 4 40 ? -39.497 48.126 -29.504 1.00 30.28 ? 39 PHE L C 1 ATOM 6037 O O . PHE D 4 40 ? -38.411 48.269 -30.047 1.00 26.18 ? 39 PHE L O 1 ATOM 6038 C CB . PHE D 4 40 ? -40.827 50.212 -29.279 1.00 23.77 ? 39 PHE L CB 1 ATOM 6039 C CG . PHE D 4 40 ? -41.345 51.322 -28.423 1.00 25.27 ? 39 PHE L CG 1 ATOM 6040 C CD1 . PHE D 4 40 ? -42.355 51.091 -27.486 1.00 26.56 ? 39 PHE L CD1 1 ATOM 6041 C CD2 . PHE D 4 40 ? -40.789 52.585 -28.483 1.00 30.73 ? 39 PHE L CD2 1 ATOM 6042 C CE1 . PHE D 4 40 ? -42.810 52.134 -26.659 1.00 27.69 ? 39 PHE L CE1 1 ATOM 6043 C CE2 . PHE D 4 40 ? -41.219 53.609 -27.631 1.00 40.92 ? 39 PHE L CE2 1 ATOM 6044 C CZ . PHE D 4 40 ? -42.239 53.364 -26.702 1.00 34.32 ? 39 PHE L CZ 1 ATOM 6045 N N . PRO D 4 41 ? -40.298 47.110 -29.822 1.00 30.29 ? 40 PRO L N 1 ATOM 6046 C CA . PRO D 4 41 ? -39.770 45.966 -30.577 1.00 30.46 ? 40 PRO L CA 1 ATOM 6047 C C . PRO D 4 41 ? -39.208 46.394 -31.928 1.00 27.35 ? 40 PRO L C 1 ATOM 6048 O O . PRO D 4 41 ? -39.837 47.184 -32.628 1.00 30.73 ? 40 PRO L O 1 ATOM 6049 C CB . PRO D 4 41 ? -41.015 45.065 -30.754 1.00 45.37 ? 40 PRO L CB 1 ATOM 6050 C CG . PRO D 4 41 ? -41.885 45.408 -29.522 1.00 38.18 ? 40 PRO L CG 1 ATOM 6051 C CD . PRO D 4 41 ? -41.711 46.912 -29.407 1.00 41.17 ? 40 PRO L CD 1 ATOM 6052 N N . GLY D 4 42 ? -38.035 45.864 -32.273 1.00 32.08 ? 41 GLY L N 1 ATOM 6053 C CA . GLY D 4 42 ? -37.424 46.190 -33.558 1.00 30.80 ? 41 GLY L CA 1 ATOM 6054 C C . GLY D 4 42 ? -36.915 47.611 -33.753 1.00 40.64 ? 41 GLY L C 1 ATOM 6055 O O . GLY D 4 42 ? -36.665 48.039 -34.873 1.00 35.69 ? 41 GLY L O 1 ATOM 6056 N N . THR D 4 43 ? -36.779 48.378 -32.685 1.00 28.99 ? 42 THR L N 1 ATOM 6057 C CA . THR D 4 43 ? -36.316 49.747 -32.823 1.00 24.89 ? 42 THR L CA 1 ATOM 6058 C C . THR D 4 43 ? -35.196 49.925 -31.782 1.00 23.18 ? 42 THR L C 1 ATOM 6059 O O . THR D 4 43 ? -35.086 49.161 -30.878 1.00 22.28 ? 42 THR L O 1 ATOM 6060 C CB . THR D 4 43 ? -37.453 50.760 -32.521 1.00 36.57 ? 42 THR L CB 1 ATOM 6061 O OG1 . THR D 4 43 ? -37.715 50.753 -31.119 1.00 42.85 ? 42 THR L OG1 1 ATOM 6062 C CG2 . THR D 4 43 ? -38.706 50.298 -33.195 1.00 41.82 ? 42 THR L CG2 1 ATOM 6063 N N . ALA D 4 44 ? -34.397 50.966 -31.887 1.00 23.29 ? 43 ALA L N 1 ATOM 6064 C CA . ALA D 4 44 ? -33.309 51.120 -30.923 1.00 22.47 ? 43 ALA L CA 1 ATOM 6065 C C . ALA D 4 44 ? -33.840 51.602 -29.579 1.00 22.18 ? 43 ALA L C 1 ATOM 6066 O O . ALA D 4 44 ? -34.855 52.281 -29.520 1.00 20.94 ? 43 ALA L O 1 ATOM 6067 C CB . ALA D 4 44 ? -32.312 52.172 -31.484 1.00 24.64 ? 43 ALA L CB 1 ATOM 6068 N N . PRO D 4 45 ? -33.117 51.303 -28.507 1.00 21.82 ? 44 PRO L N 1 ATOM 6069 C CA . PRO D 4 45 ? -33.457 51.824 -27.187 1.00 21.32 ? 44 PRO L CA 1 ATOM 6070 C C . PRO D 4 45 ? -33.405 53.351 -27.156 1.00 26.08 ? 44 PRO L C 1 ATOM 6071 O O . PRO D 4 45 ? -32.748 53.987 -28.008 1.00 23.94 ? 44 PRO L O 1 ATOM 6072 C CB . PRO D 4 45 ? -32.336 51.269 -26.288 1.00 19.76 ? 44 PRO L CB 1 ATOM 6073 C CG . PRO D 4 45 ? -31.877 50.017 -27.012 1.00 21.85 ? 44 PRO L CG 1 ATOM 6074 C CD . PRO D 4 45 ? -31.991 50.357 -28.498 1.00 21.04 ? 44 PRO L CD 1 ATOM 6075 N N . LYS D 4 46 ? -34.108 53.912 -26.180 1.00 21.09 ? 45 LYS L N 1 ATOM 6076 C CA . LYS D 4 46 ? -34.123 55.358 -25.870 1.00 23.52 ? 45 LYS L CA 1 ATOM 6077 C C . LYS D 4 46 ? -33.706 55.574 -24.446 1.00 24.80 ? 45 LYS L C 1 ATOM 6078 O O . LYS D 4 46 ? -34.147 54.860 -23.545 1.00 22.09 ? 45 LYS L O 1 ATOM 6079 C CB . LYS D 4 46 ? -35.592 55.836 -25.999 1.00 25.02 ? 45 LYS L CB 1 ATOM 6080 C CG . LYS D 4 46 ? -36.125 55.570 -27.394 1.00 37.17 ? 45 LYS L CG 1 ATOM 6081 C CD . LYS D 4 46 ? -37.596 56.038 -27.523 1.00 53.62 ? 45 LYS L CD 1 ATOM 6082 C CE . LYS D 4 46 ? -38.178 55.659 -28.890 1.00 57.51 ? 45 LYS L CE 1 ATOM 6083 N NZ . LYS D 4 46 ? -39.363 56.524 -29.136 1.00 58.64 ? 45 LYS L NZ 1 ATOM 6084 N N . LEU D 4 47 ? -32.867 56.581 -24.196 1.00 21.81 ? 46 LEU L N 1 ATOM 6085 C CA . LEU D 4 47 ? -32.483 56.896 -22.838 1.00 18.97 ? 46 LEU L CA 1 ATOM 6086 C C . LEU D 4 47 ? -33.682 57.558 -22.109 1.00 22.90 ? 46 LEU L C 1 ATOM 6087 O O . LEU D 4 47 ? -34.206 58.566 -22.573 1.00 24.99 ? 46 LEU L O 1 ATOM 6088 C CB . LEU D 4 47 ? -31.345 57.946 -22.885 1.00 24.30 ? 46 LEU L CB 1 ATOM 6089 C CG . LEU D 4 47 ? -30.788 58.283 -21.490 1.00 24.31 ? 46 LEU L CG 1 ATOM 6090 C CD1 . LEU D 4 47 ? -30.154 57.133 -20.693 1.00 22.34 ? 46 LEU L CD1 1 ATOM 6091 C CD2 . LEU D 4 47 ? -29.761 59.455 -21.729 1.00 25.12 ? 46 LEU L CD2 1 ATOM 6092 N N . LEU D 4 48 ? -34.057 56.991 -20.960 1.00 23.84 ? 47 LEU L N 1 ATOM 6093 C CA . LEU D 4 48 ? -35.179 57.505 -20.171 1.00 27.94 ? 47 LEU L CA 1 ATOM 6094 C C . LEU D 4 48 ? -34.744 58.258 -18.900 1.00 24.46 ? 47 LEU L C 1 ATOM 6095 O O . LEU D 4 48 ? -35.336 59.335 -18.593 1.00 27.59 ? 47 LEU L O 1 ATOM 6096 C CB . LEU D 4 48 ? -36.008 56.309 -19.747 1.00 32.41 ? 47 LEU L CB 1 ATOM 6097 C CG . LEU D 4 48 ? -37.494 56.326 -19.689 1.00 40.41 ? 47 LEU L CG 1 ATOM 6098 C CD1 . LEU D 4 48 ? -38.106 56.657 -21.011 1.00 32.09 ? 47 LEU L CD1 1 ATOM 6099 C CD2 . LEU D 4 48 ? -37.893 54.923 -19.172 1.00 36.63 ? 47 LEU L CD2 1 ATOM 6100 N N . ILE D 4 49 ? -33.755 57.734 -18.179 1.00 23.11 ? 48 ILE L N 1 ATOM 6101 C CA . ILE D 4 49 ? -33.242 58.336 -16.936 1.00 26.77 ? 48 ILE L CA 1 ATOM 6102 C C . ILE D 4 49 ? -31.732 58.169 -16.950 1.00 32.54 ? 48 ILE L C 1 ATOM 6103 O O . ILE D 4 49 ? -31.224 57.160 -17.447 1.00 28.04 ? 48 ILE L O 1 ATOM 6104 C CB . ILE D 4 49 ? -33.743 57.554 -15.712 1.00 30.27 ? 48 ILE L CB 1 ATOM 6105 C CG1 . ILE D 4 49 ? -35.245 57.595 -15.545 1.00 31.06 ? 48 ILE L CG1 1 ATOM 6106 C CG2 . ILE D 4 49 ? -33.036 58.015 -14.385 1.00 30.73 ? 48 ILE L CG2 1 ATOM 6107 C CD1 . ILE D 4 49 ? -35.750 58.972 -15.148 1.00 40.79 ? 48 ILE L CD1 1 ATOM 6108 N N . TYR D 4 50 ? -30.987 59.142 -16.436 1.00 25.99 ? 49 TYR L N 1 ATOM 6109 C CA . TYR D 4 50 ? -29.540 58.993 -16.294 1.00 26.49 ? 49 TYR L CA 1 ATOM 6110 C C . TYR D 4 50 ? -29.111 59.547 -14.942 1.00 36.31 ? 49 TYR L C 1 ATOM 6111 O O . TYR D 4 50 ? -29.896 60.221 -14.282 1.00 30.47 ? 49 TYR L O 1 ATOM 6112 C CB . TYR D 4 50 ? -28.788 59.729 -17.422 1.00 28.04 ? 49 TYR L CB 1 ATOM 6113 C CG . TYR D 4 50 ? -29.000 61.242 -17.459 1.00 33.88 ? 49 TYR L CG 1 ATOM 6114 C CD1 . TYR D 4 50 ? -30.044 61.800 -18.175 1.00 30.83 ? 49 TYR L CD1 1 ATOM 6115 C CD2 . TYR D 4 50 ? -28.121 62.114 -16.796 1.00 37.02 ? 49 TYR L CD2 1 ATOM 6116 C CE1 . TYR D 4 50 ? -30.264 63.175 -18.214 1.00 39.37 ? 49 TYR L CE1 1 ATOM 6117 C CE2 . TYR D 4 50 ? -28.332 63.517 -16.851 1.00 36.87 ? 49 TYR L CE2 1 ATOM 6118 C CZ . TYR D 4 50 ? -29.395 64.030 -17.552 1.00 40.27 ? 49 TYR L CZ 1 ATOM 6119 O OH . TYR D 4 50 ? -29.623 65.410 -17.617 1.00 40.12 ? 49 TYR L OH 1 ATOM 6120 N N . SER D 4 51 ? -27.878 59.263 -14.528 1.00 35.30 ? 50 SER L N 1 ATOM 6121 C CA . SER D 4 51 ? -27.442 59.624 -13.177 1.00 43.08 ? 50 SER L CA 1 ATOM 6122 C C . SER D 4 51 ? -28.466 59.321 -12.076 1.00 40.25 ? 50 SER L C 1 ATOM 6123 O O . SER D 4 51 ? -28.744 60.204 -11.244 1.00 43.30 ? 50 SER L O 1 ATOM 6124 C CB . SER D 4 51 ? -27.114 61.116 -13.129 1.00 47.55 ? 50 SER L CB 1 ATOM 6125 O OG . SER D 4 51 ? -26.109 61.409 -14.073 1.00 51.10 ? 50 SER L OG 1 ATOM 6126 N N . ASN D 4 52 ? -29.064 58.121 -12.106 1.00 29.51 ? 51 ASN L N 1 ATOM 6127 C CA . ASN D 4 52 ? -29.991 57.649 -11.075 1.00 35.65 ? 51 ASN L CA 1 ATOM 6128 C C . ASN D 4 52 ? -31.390 58.206 -11.196 1.00 32.37 ? 51 ASN L C 1 ATOM 6129 O O . ASN D 4 52 ? -32.355 57.465 -11.063 1.00 31.81 ? 51 ASN L O 1 ATOM 6130 C CB . ASN D 4 52 ? -29.451 57.951 -9.640 1.00 35.39 ? 51 ASN L CB 1 ATOM 6131 C CG . ASN D 4 52 ? -28.106 57.341 -9.394 1.00 46.62 ? 51 ASN L CG 1 ATOM 6132 O OD1 . ASN D 4 52 ? -27.840 56.231 -9.825 1.00 41.74 ? 51 ASN L OD1 1 ATOM 6133 N ND2 . ASN D 4 52 ? -27.248 58.052 -8.675 1.00 42.18 ? 51 ASN L ND2 1 ATOM 6134 N N . ASP D 4 53 ? -31.500 59.516 -11.384 1.00 30.74 ? 52 ASP L N 1 ATOM 6135 C CA . ASP D 4 53 ? -32.794 60.187 -11.199 1.00 37.94 ? 52 ASP L CA 1 ATOM 6136 C C . ASP D 4 53 ? -33.037 61.342 -12.108 1.00 38.42 ? 52 ASP L C 1 ATOM 6137 O O . ASP D 4 53 ? -34.049 62.037 -11.998 1.00 39.95 ? 52 ASP L O 1 ATOM 6138 C CB . ASP D 4 53 ? -32.972 60.676 -9.741 1.00 39.18 ? 52 ASP L CB 1 ATOM 6139 C CG . ASP D 4 53 ? -31.944 61.732 -9.322 1.00 52.03 ? 52 ASP L CG 1 ATOM 6140 O OD1 . ASP D 4 53 ? -31.210 62.306 -10.172 1.00 44.67 ? 52 ASP L OD1 1 ATOM 6141 O OD2 . ASP D 4 53 ? -31.892 61.995 -8.093 1.00 51.17 ? 52 ASP L OD2 1 ATOM 6142 N N . GLN D 4 54 ? -32.095 61.577 -12.994 1.00 32.31 ? 53 GLN L N 1 ATOM 6143 C CA . GLN D 4 54 ? -32.207 62.671 -13.966 1.00 30.02 ? 53 GLN L CA 1 ATOM 6144 C C . GLN D 4 54 ? -32.927 62.282 -15.233 1.00 41.47 ? 53 GLN L C 1 ATOM 6145 O O . GLN D 4 54 ? -32.720 61.179 -15.743 1.00 37.51 ? 53 GLN L O 1 ATOM 6146 C CB . GLN D 4 54 ? -30.830 63.198 -14.332 1.00 38.47 ? 53 GLN L CB 1 ATOM 6147 C CG . GLN D 4 54 ? -30.005 63.635 -13.129 1.00 45.22 ? 53 GLN L CG 1 ATOM 6148 C CD . GLN D 4 54 ? -30.668 64.813 -12.414 1.00 56.15 ? 53 GLN L CD 1 ATOM 6149 O OE1 . GLN D 4 54 ? -30.787 65.915 -12.973 1.00 45.95 ? 53 GLN L OE1 1 ATOM 6150 N NE2 . GLN D 4 54 ? -31.157 64.561 -11.203 1.00 50.85 ? 53 GLN L NE2 1 ATOM 6151 N N . ARG D 4 55 ? -33.730 63.201 -15.770 1.00 34.73 ? 54 ARG L N 1 ATOM 6152 C CA . ARG D 4 55 ? -34.608 62.913 -16.901 1.00 31.53 ? 54 ARG L CA 1 ATOM 6153 C C . ARG D 4 55 ? -34.289 63.806 -18.069 1.00 36.50 ? 54 ARG L C 1 ATOM 6154 O O . ARG D 4 55 ? -34.271 65.025 -17.913 1.00 42.46 ? 54 ARG L O 1 ATOM 6155 C CB . ARG D 4 55 ? -36.042 63.150 -16.451 1.00 39.89 ? 54 ARG L CB 1 ATOM 6156 C CG . ARG D 4 55 ? -37.125 62.753 -17.386 1.00 43.25 ? 54 ARG L CG 1 ATOM 6157 C CD . ARG D 4 55 ? -38.470 62.730 -16.637 1.00 44.21 ? 54 ARG L CD 1 ATOM 6158 N NE . ARG D 4 55 ? -38.691 63.960 -15.856 1.00 53.40 ? 54 ARG L NE 1 ATOM 6159 C CZ . ARG D 4 55 ? -38.931 65.162 -16.395 1.00 55.43 ? 54 ARG L CZ 1 ATOM 6160 N NH1 . ARG D 4 55 ? -38.971 65.335 -17.722 1.00 48.02 ? 54 ARG L NH1 1 ATOM 6161 N NH2 . ARG D 4 55 ? -39.112 66.204 -15.602 1.00 56.09 ? 54 ARG L NH2 1 ATOM 6162 N N . PRO D 4 56 ? -34.015 63.226 -19.253 1.00 39.97 ? 55 PRO L N 1 ATOM 6163 C CA . PRO D 4 56 ? -33.847 64.063 -20.443 1.00 34.24 ? 55 PRO L CA 1 ATOM 6164 C C . PRO D 4 56 ? -35.051 64.908 -20.679 1.00 41.25 ? 55 PRO L C 1 ATOM 6165 O O . PRO D 4 56 ? -36.162 64.510 -20.315 1.00 37.86 ? 55 PRO L O 1 ATOM 6166 C CB . PRO D 4 56 ? -33.733 63.044 -21.575 1.00 35.77 ? 55 PRO L CB 1 ATOM 6167 C CG . PRO D 4 56 ? -33.067 61.914 -20.947 1.00 31.95 ? 55 PRO L CG 1 ATOM 6168 C CD . PRO D 4 56 ? -33.690 61.815 -19.548 1.00 31.22 ? 55 PRO L CD 1 ATOM 6169 N N . SER D 4 57 ? -34.838 66.060 -21.302 1.00 43.93 ? 56 SER L N 1 ATOM 6170 C CA . SER D 4 57 ? -35.894 67.051 -21.398 1.00 47.82 ? 56 SER L CA 1 ATOM 6171 C C . SER D 4 57 ? -37.053 66.508 -22.215 1.00 47.84 ? 56 SER L C 1 ATOM 6172 O O . SER D 4 57 ? -38.219 66.814 -21.937 1.00 44.64 ? 56 SER L O 1 ATOM 6173 C CB . SER D 4 57 ? -35.371 68.374 -21.985 1.00 48.85 ? 56 SER L CB 1 ATOM 6174 O OG . SER D 4 57 ? -35.125 68.258 -23.374 1.00 57.98 ? 56 SER L OG 1 ATOM 6175 N N . VAL D 4 58 ? -36.748 65.639 -23.173 1.00 45.97 ? 57 VAL L N 1 ATOM 6176 C CA . VAL D 4 58 ? -37.790 65.076 -24.035 1.00 38.29 ? 57 VAL L CA 1 ATOM 6177 C C . VAL D 4 58 ? -38.631 63.931 -23.378 1.00 35.03 ? 57 VAL L C 1 ATOM 6178 O O . VAL D 4 58 ? -39.674 63.553 -23.896 1.00 39.92 ? 57 VAL L O 1 ATOM 6179 C CB . VAL D 4 58 ? -37.240 64.686 -25.434 1.00 48.05 ? 57 VAL L CB 1 ATOM 6180 C CG1 . VAL D 4 58 ? -36.426 63.381 -25.379 1.00 45.42 ? 57 VAL L CG1 1 ATOM 6181 C CG2 . VAL D 4 58 ? -38.364 64.542 -26.427 1.00 63.11 ? 57 VAL L CG2 1 ATOM 6182 N N . VAL D 4 59 ? -38.201 63.440 -22.230 1.00 32.11 ? 58 VAL L N 1 ATOM 6183 C CA . VAL D 4 59 ? -38.912 62.343 -21.534 1.00 33.37 ? 58 VAL L CA 1 ATOM 6184 C C . VAL D 4 59 ? -39.987 62.885 -20.571 1.00 40.36 ? 58 VAL L C 1 ATOM 6185 O O . VAL D 4 59 ? -39.664 63.694 -19.707 1.00 42.17 ? 58 VAL L O 1 ATOM 6186 C CB . VAL D 4 59 ? -37.918 61.526 -20.738 1.00 35.98 ? 58 VAL L CB 1 ATOM 6187 C CG1 . VAL D 4 59 ? -38.607 60.457 -19.838 1.00 35.18 ? 58 VAL L CG1 1 ATOM 6188 C CG2 . VAL D 4 59 ? -36.915 60.855 -21.704 1.00 36.02 ? 58 VAL L CG2 1 ATOM 6189 N N . PRO D 4 60 ? -41.248 62.410 -20.707 1.00 38.82 ? 59 PRO L N 1 ATOM 6190 C CA . PRO D 4 60 ? -42.346 62.867 -19.842 1.00 47.13 ? 59 PRO L CA 1 ATOM 6191 C C . PRO D 4 60 ? -42.016 62.727 -18.363 1.00 50.13 ? 59 PRO L C 1 ATOM 6192 O O . PRO D 4 60 ? -41.303 61.786 -17.943 1.00 36.08 ? 59 PRO L O 1 ATOM 6193 C CB . PRO D 4 60 ? -43.510 61.934 -20.217 1.00 43.47 ? 59 PRO L CB 1 ATOM 6194 C CG . PRO D 4 60 ? -43.192 61.448 -21.603 1.00 44.31 ? 59 PRO L CG 1 ATOM 6195 C CD . PRO D 4 60 ? -41.681 61.352 -21.636 1.00 37.70 ? 59 PRO L CD 1 ATOM 6196 N N . ASP D 4 61 ? -42.563 63.641 -17.560 1.00 38.04 ? 60 ASP L N 1 ATOM 6197 C CA . ASP D 4 61 ? -42.262 63.647 -16.148 1.00 37.19 ? 60 ASP L CA 1 ATOM 6198 C C . ASP D 4 61 ? -42.923 62.511 -15.366 1.00 35.09 ? 60 ASP L C 1 ATOM 6199 O O . ASP D 4 61 ? -42.599 62.314 -14.206 1.00 41.25 ? 60 ASP L O 1 ATOM 6200 C CB . ASP D 4 61 ? -42.539 65.019 -15.500 1.00 57.55 ? 60 ASP L CB 1 ATOM 6201 C CG . ASP D 4 61 ? -43.951 65.523 -15.761 1.00 65.38 ? 60 ASP L CG 1 ATOM 6202 O OD1 . ASP D 4 61 ? -44.782 64.736 -16.276 1.00 53.66 ? 60 ASP L OD1 1 ATOM 6203 O OD2 . ASP D 4 61 ? -44.226 66.709 -15.456 1.00 60.75 ? 60 ASP L OD2 1 ATOM 6204 N N . ARG D 4 62 ? -43.796 61.733 -16.004 1.00 40.30 ? 61 ARG L N 1 ATOM 6205 C CA . ARG D 4 62 ? -44.337 60.512 -15.370 1.00 37.69 ? 61 ARG L CA 1 ATOM 6206 C C . ARG D 4 62 ? -43.275 59.442 -15.134 1.00 32.47 ? 61 ARG L C 1 ATOM 6207 O O . ARG D 4 62 ? -43.484 58.514 -14.332 1.00 34.23 ? 61 ARG L O 1 ATOM 6208 C CB . ARG D 4 62 ? -45.531 59.934 -16.133 1.00 39.48 ? 61 ARG L CB 1 ATOM 6209 C CG . ARG D 4 62 ? -45.244 59.299 -17.496 1.00 40.28 ? 61 ARG L CG 1 ATOM 6210 C CD . ARG D 4 62 ? -46.447 58.456 -17.964 1.00 42.31 ? 61 ARG L CD 1 ATOM 6211 N NE . ARG D 4 62 ? -46.333 58.009 -19.332 1.00 37.77 ? 61 ARG L NE 1 ATOM 6212 C CZ . ARG D 4 62 ? -46.372 58.829 -20.386 1.00 42.04 ? 61 ARG L CZ 1 ATOM 6213 N NH1 . ARG D 4 62 ? -46.561 60.138 -20.215 1.00 45.23 ? 61 ARG L NH1 1 ATOM 6214 N NH2 . ARG D 4 62 ? -46.251 58.346 -21.619 1.00 43.40 ? 61 ARG L NH2 1 ATOM 6215 N N . PHE D 4 63 ? -42.106 59.617 -15.760 1.00 32.56 ? 62 PHE L N 1 ATOM 6216 C CA . PHE D 4 63 ? -41.004 58.692 -15.522 1.00 33.74 ? 62 PHE L CA 1 ATOM 6217 C C . PHE D 4 63 ? -40.040 59.222 -14.455 1.00 26.36 ? 62 PHE L C 1 ATOM 6218 O O . PHE D 4 63 ? -39.550 60.344 -14.557 1.00 37.32 ? 62 PHE L O 1 ATOM 6219 C CB . PHE D 4 63 ? -40.210 58.472 -16.817 1.00 29.61 ? 62 PHE L CB 1 ATOM 6220 C CG . PHE D 4 63 ? -40.965 57.743 -17.870 1.00 29.87 ? 62 PHE L CG 1 ATOM 6221 C CD1 . PHE D 4 63 ? -40.982 56.346 -17.872 1.00 36.54 ? 62 PHE L CD1 1 ATOM 6222 C CD2 . PHE D 4 63 ? -41.617 58.433 -18.877 1.00 30.05 ? 62 PHE L CD2 1 ATOM 6223 C CE1 . PHE D 4 63 ? -41.685 55.646 -18.822 1.00 26.73 ? 62 PHE L CE1 1 ATOM 6224 C CE2 . PHE D 4 63 ? -42.349 57.749 -19.852 1.00 37.60 ? 62 PHE L CE2 1 ATOM 6225 C CZ . PHE D 4 63 ? -42.381 56.358 -19.836 1.00 26.32 ? 62 PHE L CZ 1 ATOM 6226 N N . SER D 4 64 ? -39.736 58.401 -13.461 1.00 29.93 ? 63 SER L N 1 ATOM 6227 C CA . SER D 4 64 ? -38.780 58.825 -12.469 1.00 35.79 ? 63 SER L CA 1 ATOM 6228 C C . SER D 4 64 ? -37.926 57.658 -12.006 1.00 37.16 ? 63 SER L C 1 ATOM 6229 O O . SER D 4 64 ? -38.331 56.485 -12.066 1.00 35.68 ? 63 SER L O 1 ATOM 6230 C CB . SER D 4 64 ? -39.521 59.488 -11.263 1.00 33.89 ? 63 SER L CB 1 ATOM 6231 O OG . SER D 4 64 ? -40.281 58.530 -10.562 1.00 39.46 ? 63 SER L OG 1 ATOM 6232 N N . GLY D 4 65 ? -36.705 57.962 -11.571 1.00 33.43 ? 64 GLY L N 1 ATOM 6233 C CA . GLY D 4 65 ? -35.870 56.898 -11.083 1.00 31.35 ? 64 GLY L CA 1 ATOM 6234 C C . GLY D 4 65 ? -35.269 57.191 -9.736 1.00 37.00 ? 64 GLY L C 1 ATOM 6235 O O . GLY D 4 65 ? -35.128 58.338 -9.353 1.00 40.48 ? 64 GLY L O 1 ATOM 6236 N N . SER D 4 66 ? -34.900 56.142 -9.034 1.00 38.08 ? 65 SER L N 1 ATOM 6237 C CA . SER D 4 66 ? -34.211 56.318 -7.770 1.00 43.94 ? 65 SER L CA 1 ATOM 6238 C C . SER D 4 66 ? -33.235 55.159 -7.506 1.00 50.47 ? 65 SER L C 1 ATOM 6239 O O . SER D 4 66 ? -33.333 54.088 -8.124 1.00 40.50 ? 65 SER L O 1 ATOM 6240 C CB . SER D 4 66 ? -35.266 56.413 -6.668 1.00 38.10 ? 65 SER L CB 1 ATOM 6241 O OG . SER D 4 66 ? -36.004 55.202 -6.552 1.00 45.32 ? 65 SER L OG 1 ATOM 6242 N N . LYS D 4 67 ? -32.321 55.361 -6.558 1.00 41.22 ? 66 LYS L N 1 ATOM 6243 C CA . LYS D 4 67 ? -31.283 54.382 -6.236 1.00 52.19 ? 66 LYS L CA 1 ATOM 6244 C C . LYS D 4 67 ? -31.070 54.308 -4.721 1.00 49.92 ? 66 LYS L C 1 ATOM 6245 O O . LYS D 4 67 ? -30.855 55.317 -4.080 1.00 48.06 ? 66 LYS L O 1 ATOM 6246 C CB . LYS D 4 67 ? -29.971 54.808 -6.906 1.00 51.48 ? 66 LYS L CB 1 ATOM 6247 C CG . LYS D 4 67 ? -28.701 54.117 -6.401 1.00 51.29 ? 66 LYS L CG 1 ATOM 6248 C CD . LYS D 4 67 ? -27.500 54.827 -7.000 1.00 49.69 ? 66 LYS L CD 1 ATOM 6249 C CE . LYS D 4 67 ? -26.218 54.466 -6.325 1.00 55.13 ? 66 LYS L CE 1 ATOM 6250 N NZ . LYS D 4 67 ? -25.070 55.149 -6.987 1.00 59.91 ? 66 LYS L NZ 1 ATOM 6251 N N . SER D 4 68 ? -31.126 53.115 -4.147 1.00 48.54 ? 67 SER L N 1 ATOM 6252 C CA . SER D 4 68 ? -30.755 52.998 -2.749 1.00 47.07 ? 67 SER L CA 1 ATOM 6253 C C . SER D 4 68 ? -29.976 51.733 -2.507 1.00 48.95 ? 67 SER L C 1 ATOM 6254 O O . SER D 4 68 ? -30.417 50.612 -2.822 1.00 47.07 ? 67 SER L O 1 ATOM 6255 C CB . SER D 4 68 ? -31.982 53.110 -1.825 1.00 49.19 ? 67 SER L CB 1 ATOM 6256 O OG . SER D 4 68 ? -32.242 51.870 -1.190 1.00 64.55 ? 67 SER L OG 1 ATOM 6257 N N . GLY D 4 69 ? -28.799 51.914 -1.928 1.00 47.28 ? 68 GLY L N 1 ATOM 6258 C CA . GLY D 4 69 ? -27.952 50.781 -1.669 1.00 49.79 ? 68 GLY L CA 1 ATOM 6259 C C . GLY D 4 69 ? -27.488 50.265 -3.010 1.00 47.58 ? 68 GLY L C 1 ATOM 6260 O O . GLY D 4 69 ? -26.940 51.004 -3.805 1.00 47.03 ? 68 GLY L O 1 ATOM 6261 N N . THR D 4 70 ? -27.714 48.987 -3.237 1.00 46.67 ? 69 THR L N 1 ATOM 6262 C CA . THR D 4 70 ? -27.284 48.366 -4.474 1.00 61.09 ? 69 THR L CA 1 ATOM 6263 C C . THR D 4 70 ? -28.511 48.032 -5.313 1.00 58.34 ? 69 THR L C 1 ATOM 6264 O O . THR D 4 70 ? -28.516 47.049 -6.083 1.00 45.63 ? 69 THR L O 1 ATOM 6265 C CB . THR D 4 70 ? -26.575 47.088 -4.163 1.00 53.11 ? 69 THR L CB 1 ATOM 6266 O OG1 . THR D 4 70 ? -27.505 46.204 -3.508 1.00 50.04 ? 69 THR L OG1 1 ATOM 6267 C CG2 . THR D 4 70 ? -25.384 47.375 -3.253 1.00 51.83 ? 69 THR L CG2 1 ATOM 6268 N N . SER D 4 71 ? -29.555 48.841 -5.138 1.00 50.68 ? 70 SER L N 1 ATOM 6269 C CA . SER D 4 71 ? -30.823 48.627 -5.822 1.00 54.08 ? 70 SER L CA 1 ATOM 6270 C C . SER D 4 71 ? -31.243 49.896 -6.550 1.00 52.14 ? 70 SER L C 1 ATOM 6271 O O . SER D 4 71 ? -30.757 50.990 -6.238 1.00 51.01 ? 70 SER L O 1 ATOM 6272 C CB . SER D 4 71 ? -31.895 48.180 -4.836 1.00 59.24 ? 70 SER L CB 1 ATOM 6273 O OG . SER D 4 71 ? -32.062 46.771 -4.879 1.00 63.89 ? 70 SER L OG 1 ATOM 6274 N N . ALA D 4 72 ? -32.092 49.754 -7.570 1.00 43.61 ? 71 ALA L N 1 ATOM 6275 C CA . ALA D 4 72 ? -32.616 50.927 -8.250 1.00 37.10 ? 71 ALA L CA 1 ATOM 6276 C C . ALA D 4 72 ? -34.036 50.659 -8.679 1.00 29.06 ? 71 ALA L C 1 ATOM 6277 O O . ALA D 4 72 ? -34.482 49.516 -8.792 1.00 33.91 ? 71 ALA L O 1 ATOM 6278 C CB . ALA D 4 72 ? -31.730 51.350 -9.469 1.00 33.61 ? 71 ALA L CB 1 ATOM 6279 N N . SER D 4 73 ? -34.764 51.721 -8.903 1.00 28.93 ? 72 SER L N 1 ATOM 6280 C CA . SER D 4 73 ? -36.163 51.579 -9.252 1.00 40.45 ? 72 SER L CA 1 ATOM 6281 C C . SER D 4 73 ? -36.575 52.615 -10.270 1.00 32.28 ? 72 SER L C 1 ATOM 6282 O O . SER D 4 73 ? -36.203 53.782 -10.193 1.00 35.50 ? 72 SER L O 1 ATOM 6283 C CB . SER D 4 73 ? -37.053 51.690 -7.992 1.00 38.79 ? 72 SER L CB 1 ATOM 6284 O OG . SER D 4 73 ? -38.333 51.181 -8.275 1.00 44.55 ? 72 SER L OG 1 ATOM 6285 N N . LEU D 4 74 ? -37.338 52.175 -11.263 1.00 32.71 ? 73 LEU L N 1 ATOM 6286 C CA . LEU D 4 74 ? -37.917 53.087 -12.214 1.00 25.90 ? 73 LEU L CA 1 ATOM 6287 C C . LEU D 4 74 ? -39.395 53.128 -11.901 1.00 31.50 ? 73 LEU L C 1 ATOM 6288 O O . LEU D 4 74 ? -40.011 52.077 -11.795 1.00 32.49 ? 73 LEU L O 1 ATOM 6289 C CB . LEU D 4 74 ? -37.755 52.569 -13.671 1.00 26.61 ? 73 LEU L CB 1 ATOM 6290 C CG . LEU D 4 74 ? -38.426 53.384 -14.803 1.00 28.93 ? 73 LEU L CG 1 ATOM 6291 C CD1 . LEU D 4 74 ? -37.811 54.711 -15.118 1.00 29.19 ? 73 LEU L CD1 1 ATOM 6292 C CD2 . LEU D 4 74 ? -38.489 52.528 -16.080 1.00 30.53 ? 73 LEU L CD2 1 ATOM 6293 N N . ALA D 4 75 ? -39.949 54.316 -11.767 1.00 33.18 ? 74 ALA L N 1 ATOM 6294 C CA . ALA D 4 75 ? -41.409 54.456 -11.575 1.00 30.69 ? 74 ALA L CA 1 ATOM 6295 C C . ALA D 4 75 ? -42.065 55.185 -12.739 1.00 28.04 ? 74 ALA L C 1 ATOM 6296 O O . ALA D 4 75 ? -41.604 56.254 -13.195 1.00 30.42 ? 74 ALA L O 1 ATOM 6297 C CB . ALA D 4 75 ? -41.702 55.200 -10.256 1.00 33.33 ? 74 ALA L CB 1 ATOM 6298 N N . ILE D 4 76 ? -43.197 54.640 -13.193 1.00 31.82 ? 75 ILE L N 1 ATOM 6299 C CA . ILE D 4 76 ? -43.955 55.275 -14.243 1.00 31.96 ? 75 ILE L CA 1 ATOM 6300 C C . ILE D 4 76 ? -45.288 55.635 -13.572 1.00 42.60 ? 75 ILE L C 1 ATOM 6301 O O . ILE D 4 76 ? -46.072 54.753 -13.232 1.00 34.05 ? 75 ILE L O 1 ATOM 6302 C CB . ILE D 4 76 ? -44.221 54.343 -15.437 1.00 33.48 ? 75 ILE L CB 1 ATOM 6303 C CG1 . ILE D 4 76 ? -42.920 53.853 -16.041 1.00 34.85 ? 75 ILE L CG1 1 ATOM 6304 C CG2 . ILE D 4 76 ? -45.037 55.069 -16.486 1.00 36.33 ? 75 ILE L CG2 1 ATOM 6305 C CD1 . ILE D 4 76 ? -43.112 52.787 -17.025 1.00 35.39 ? 75 ILE L CD1 1 ATOM 6306 N N . SER D 4 77 ? -45.483 56.918 -13.301 1.00 41.18 ? 76 SER L N 1 ATOM 6307 C CA . SER D 4 77 ? -46.737 57.371 -12.700 1.00 46.73 ? 76 SER L CA 1 ATOM 6308 C C . SER D 4 77 ? -47.670 57.453 -13.885 1.00 47.96 ? 76 SER L C 1 ATOM 6309 O O . SER D 4 77 ? -47.210 57.628 -15.036 1.00 50.88 ? 76 SER L O 1 ATOM 6310 C CB . SER D 4 77 ? -46.554 58.752 -12.103 1.00 39.24 ? 76 SER L CB 1 ATOM 6311 O OG . SER D 4 77 ? -46.861 59.706 -13.115 1.00 49.01 ? 76 SER L OG 1 ATOM 6312 N N . GLY D 4 78 ? -48.964 57.279 -13.651 1.00 41.65 ? 77 GLY L N 1 ATOM 6313 C CA . GLY D 4 78 ? -49.936 57.512 -14.706 1.00 38.36 ? 77 GLY L CA 1 ATOM 6314 C C . GLY D 4 78 ? -49.716 56.780 -16.031 1.00 37.77 ? 77 GLY L C 1 ATOM 6315 O O . GLY D 4 78 ? -49.683 57.395 -17.104 1.00 35.21 ? 77 GLY L O 1 ATOM 6316 N N . LEU D 4 79 ? -49.626 55.458 -15.954 1.00 35.43 ? 78 LEU L N 1 ATOM 6317 C CA . LEU D 4 79 ? -49.328 54.630 -17.138 1.00 34.78 ? 78 LEU L CA 1 ATOM 6318 C C . LEU D 4 79 ? -50.160 54.963 -18.350 1.00 36.97 ? 78 LEU L C 1 ATOM 6319 O O . LEU D 4 79 ? -51.364 55.149 -18.260 1.00 35.47 ? 78 LEU L O 1 ATOM 6320 C CB . LEU D 4 79 ? -49.509 53.170 -16.790 1.00 28.18 ? 78 LEU L CB 1 ATOM 6321 C CG . LEU D 4 79 ? -48.987 52.134 -17.734 1.00 33.59 ? 78 LEU L CG 1 ATOM 6322 C CD1 . LEU D 4 79 ? -47.433 52.208 -17.699 1.00 30.73 ? 78 LEU L CD1 1 ATOM 6323 C CD2 . LEU D 4 79 ? -49.473 50.753 -17.233 1.00 33.46 ? 78 LEU L CD2 1 ATOM 6324 N N . GLN D 4 80 ? -49.506 55.096 -19.493 1.00 36.44 ? 79 GLN L N 1 ATOM 6325 C CA . GLN D 4 80 ? -50.190 55.322 -20.761 1.00 32.68 ? 79 GLN L CA 1 ATOM 6326 C C . GLN D 4 80 ? -49.991 54.132 -21.654 1.00 36.74 ? 79 GLN L C 1 ATOM 6327 O O . GLN D 4 80 ? -48.995 53.394 -21.520 1.00 32.51 ? 79 GLN L O 1 ATOM 6328 C CB . GLN D 4 80 ? -49.615 56.540 -21.484 1.00 37.36 ? 79 GLN L CB 1 ATOM 6329 C CG . GLN D 4 80 ? -49.645 57.797 -20.678 1.00 40.38 ? 79 GLN L CG 1 ATOM 6330 C CD . GLN D 4 80 ? -51.053 58.357 -20.513 1.00 50.77 ? 79 GLN L CD 1 ATOM 6331 O OE1 . GLN D 4 80 ? -51.743 58.673 -21.503 1.00 57.01 ? 79 GLN L OE1 1 ATOM 6332 N NE2 . GLN D 4 80 ? -51.486 58.490 -19.254 1.00 55.05 ? 79 GLN L NE2 1 ATOM 6333 N N . SER D 4 81 ? -50.895 53.948 -22.610 1.00 30.68 ? 80 SER L N 1 ATOM 6334 C CA . SER D 4 81 ? -50.802 52.806 -23.502 1.00 32.27 ? 80 SER L CA 1 ATOM 6335 C C . SER D 4 81 ? -49.466 52.804 -24.275 1.00 33.58 ? 80 SER L C 1 ATOM 6336 O O . SER D 4 81 ? -48.894 51.740 -24.546 1.00 30.37 ? 80 SER L O 1 ATOM 6337 C CB . SER D 4 81 ? -51.970 52.785 -24.501 1.00 42.02 ? 80 SER L CB 1 ATOM 6338 O OG . SER D 4 81 ? -51.973 53.967 -25.270 1.00 65.06 ? 80 SER L OG 1 ATOM 6339 N N . GLU D 4 82 ? -48.958 53.990 -24.575 1.00 31.41 ? 81 GLU L N 1 ATOM 6340 C CA . GLU D 4 82 ? -47.736 54.030 -25.394 1.00 34.38 ? 81 GLU L CA 1 ATOM 6341 C C . GLU D 4 82 ? -46.515 53.603 -24.592 1.00 33.75 ? 81 GLU L C 1 ATOM 6342 O O . GLU D 4 82 ? -45.400 53.512 -25.140 1.00 32.11 ? 81 GLU L O 1 ATOM 6343 C CB . GLU D 4 82 ? -47.541 55.412 -26.013 1.00 38.37 ? 81 GLU L CB 1 ATOM 6344 C CG . GLU D 4 82 ? -47.549 56.533 -25.025 1.00 38.48 ? 81 GLU L CG 1 ATOM 6345 C CD . GLU D 4 82 ? -48.991 57.113 -24.788 1.00 59.04 ? 81 GLU L CD 1 ATOM 6346 O OE1 . GLU D 4 82 ? -50.021 56.445 -25.148 1.00 46.93 ? 81 GLU L OE1 1 ATOM 6347 O OE2 . GLU D 4 82 ? -49.078 58.243 -24.236 1.00 63.34 ? 81 GLU L OE2 1 ATOM 6348 N N . ASP D 4 83 ? -46.693 53.333 -23.289 1.00 27.75 ? 82 ASP L N 1 ATOM 6349 C CA . ASP D 4 83 ? -45.560 52.899 -22.452 1.00 27.32 ? 82 ASP L CA 1 ATOM 6350 C C . ASP D 4 83 ? -45.298 51.410 -22.515 1.00 24.92 ? 82 ASP L C 1 ATOM 6351 O O . ASP D 4 83 ? -44.348 50.909 -21.890 1.00 26.63 ? 82 ASP L O 1 ATOM 6352 C CB . ASP D 4 83 ? -45.742 53.328 -20.989 1.00 29.31 ? 82 ASP L CB 1 ATOM 6353 C CG . ASP D 4 83 ? -45.938 54.848 -20.830 1.00 39.29 ? 82 ASP L CG 1 ATOM 6354 O OD1 . ASP D 4 83 ? -45.410 55.656 -21.639 1.00 31.11 ? 82 ASP L OD1 1 ATOM 6355 O OD2 . ASP D 4 83 ? -46.636 55.258 -19.895 1.00 32.00 ? 82 ASP L OD2 1 ATOM 6356 N N . GLU D 4 84 ? -46.127 50.659 -23.224 1.00 27.26 ? 83 GLU L N 1 ATOM 6357 C CA . GLU D 4 84 ? -45.855 49.225 -23.359 1.00 23.20 ? 83 GLU L CA 1 ATOM 6358 C C . GLU D 4 84 ? -44.551 49.060 -24.180 1.00 31.08 ? 83 GLU L C 1 ATOM 6359 O O . GLU D 4 84 ? -44.474 49.460 -25.340 1.00 26.76 ? 83 GLU L O 1 ATOM 6360 C CB . GLU D 4 84 ? -47.056 48.576 -24.072 1.00 25.83 ? 83 GLU L CB 1 ATOM 6361 C CG . GLU D 4 84 ? -46.953 47.093 -24.279 1.00 27.55 ? 83 GLU L CG 1 ATOM 6362 C CD . GLU D 4 84 ? -48.336 46.476 -24.571 1.00 49.55 ? 83 GLU L CD 1 ATOM 6363 O OE1 . GLU D 4 84 ? -49.139 46.309 -23.632 1.00 37.63 ? 83 GLU L OE1 1 ATOM 6364 O OE2 . GLU D 4 84 ? -48.635 46.179 -25.737 1.00 59.79 ? 83 GLU L OE2 1 ATOM 6365 N N . ALA D 4 85 ? -43.550 48.462 -23.563 1.00 25.94 ? 84 ALA L N 1 ATOM 6366 C CA . ALA D 4 85 ? -42.195 48.410 -24.113 1.00 22.25 ? 84 ALA L CA 1 ATOM 6367 C C . ALA D 4 85 ? -41.330 47.554 -23.208 1.00 26.80 ? 84 ALA L C 1 ATOM 6368 O O . ALA D 4 85 ? -41.786 47.088 -22.149 1.00 25.02 ? 84 ALA L O 1 ATOM 6369 C CB . ALA D 4 85 ? -41.629 49.816 -24.149 1.00 20.65 ? 84 ALA L CB 1 ATOM 6370 N N . GLU D 4 86 ? -40.086 47.289 -23.636 1.00 22.26 ? 85 GLU L N 1 ATOM 6371 C CA . GLU D 4 86 ? -39.105 46.655 -22.752 1.00 21.63 ? 85 GLU L CA 1 ATOM 6372 C C . GLU D 4 86 ? -38.311 47.769 -22.014 1.00 24.12 ? 85 GLU L C 1 ATOM 6373 O O . GLU D 4 86 ? -38.029 48.810 -22.617 1.00 23.58 ? 85 GLU L O 1 ATOM 6374 C CB . GLU D 4 86 ? -38.140 45.759 -23.584 1.00 22.22 ? 85 GLU L CB 1 ATOM 6375 C CG . GLU D 4 86 ? -37.241 44.883 -22.677 1.00 29.42 ? 85 GLU L CG 1 ATOM 6376 C CD . GLU D 4 86 ? -37.881 43.564 -22.342 1.00 45.67 ? 85 GLU L CD 1 ATOM 6377 O OE1 . GLU D 4 86 ? -39.063 43.406 -22.748 1.00 41.98 ? 85 GLU L OE1 1 ATOM 6378 O OE2 . GLU D 4 86 ? -37.208 42.697 -21.694 1.00 39.57 ? 85 GLU L OE2 1 ATOM 6379 N N . TYR D 4 87 ? -37.970 47.577 -20.734 1.00 20.15 ? 86 TYR L N 1 ATOM 6380 C CA . TYR D 4 87 ? -37.207 48.567 -19.988 1.00 23.45 ? 86 TYR L CA 1 ATOM 6381 C C . TYR D 4 87 ? -35.927 47.927 -19.469 1.00 23.37 ? 86 TYR L C 1 ATOM 6382 O O . TYR D 4 87 ? -35.945 46.824 -18.902 1.00 24.22 ? 86 TYR L O 1 ATOM 6383 C CB . TYR D 4 87 ? -38.038 49.170 -18.807 1.00 22.43 ? 86 TYR L CB 1 ATOM 6384 C CG . TYR D 4 87 ? -39.193 49.986 -19.328 1.00 20.07 ? 86 TYR L CG 1 ATOM 6385 C CD1 . TYR D 4 87 ? -40.401 49.360 -19.748 1.00 21.26 ? 86 TYR L CD1 1 ATOM 6386 C CD2 . TYR D 4 87 ? -39.082 51.351 -19.449 1.00 20.11 ? 86 TYR L CD2 1 ATOM 6387 C CE1 . TYR D 4 87 ? -41.457 50.143 -20.288 1.00 20.29 ? 86 TYR L CE1 1 ATOM 6388 C CE2 . TYR D 4 87 ? -40.141 52.144 -19.977 1.00 19.91 ? 86 TYR L CE2 1 ATOM 6389 C CZ . TYR D 4 87 ? -41.327 51.510 -20.374 1.00 20.69 ? 86 TYR L CZ 1 ATOM 6390 O OH . TYR D 4 87 ? -42.330 52.270 -20.923 1.00 24.89 ? 86 TYR L OH 1 ATOM 6391 N N . TYR D 4 88 ? -34.810 48.614 -19.651 1.00 20.77 ? 87 TYR L N 1 ATOM 6392 C CA . TYR D 4 88 ? -33.522 48.118 -19.158 1.00 22.90 ? 87 TYR L CA 1 ATOM 6393 C C . TYR D 4 88 ? -32.883 49.094 -18.199 1.00 20.04 ? 87 TYR L C 1 ATOM 6394 O O . TYR D 4 88 ? -32.763 50.314 -18.487 1.00 21.74 ? 87 TYR L O 1 ATOM 6395 C CB . TYR D 4 88 ? -32.488 47.948 -20.328 1.00 19.22 ? 87 TYR L CB 1 ATOM 6396 C CG . TYR D 4 88 ? -32.882 46.873 -21.294 1.00 16.96 ? 87 TYR L CG 1 ATOM 6397 C CD1 . TYR D 4 88 ? -32.506 45.543 -21.045 1.00 20.53 ? 87 TYR L CD1 1 ATOM 6398 C CD2 . TYR D 4 88 ? -33.675 47.171 -22.425 1.00 20.33 ? 87 TYR L CD2 1 ATOM 6399 C CE1 . TYR D 4 88 ? -32.920 44.538 -21.899 1.00 24.34 ? 87 TYR L CE1 1 ATOM 6400 C CE2 . TYR D 4 88 ? -34.080 46.155 -23.316 1.00 21.35 ? 87 TYR L CE2 1 ATOM 6401 C CZ . TYR D 4 88 ? -33.709 44.858 -23.028 1.00 23.52 ? 87 TYR L CZ 1 ATOM 6402 O OH . TYR D 4 88 ? -34.090 43.826 -23.899 1.00 24.16 ? 87 TYR L OH 1 ATOM 6403 N N . CYS D 4 89 ? -32.392 48.559 -17.086 1.00 22.66 ? 88 CYS L N 1 ATOM 6404 C CA . CYS D 4 89 ? -31.496 49.351 -16.247 1.00 24.18 ? 88 CYS L CA 1 ATOM 6405 C C . CYS D 4 89 ? -30.029 49.095 -16.668 1.00 24.08 ? 88 CYS L C 1 ATOM 6406 O O . CYS D 4 89 ? -29.748 48.125 -17.356 1.00 24.29 ? 88 CYS L O 1 ATOM 6407 C CB . CYS D 4 89 ? -31.705 49.033 -14.747 1.00 25.41 ? 88 CYS L CB 1 ATOM 6408 S SG . CYS D 4 89 ? -31.404 47.328 -14.320 1.00 32.19 ? 88 CYS L SG 1 ATOM 6409 N N . ALA D 4 90 ? -29.120 49.986 -16.307 1.00 21.59 ? 89 ALA L N 1 ATOM 6410 C CA . ALA D 4 90 ? -27.710 49.857 -16.731 1.00 22.14 ? 89 ALA L CA 1 ATOM 6411 C C . ALA D 4 90 ? -26.813 50.643 -15.793 1.00 25.46 ? 89 ALA L C 1 ATOM 6412 O O . ALA D 4 90 ? -27.237 51.653 -15.245 1.00 27.34 ? 89 ALA L O 1 ATOM 6413 C CB . ALA D 4 90 ? -27.486 50.360 -18.120 1.00 20.63 ? 89 ALA L CB 1 ATOM 6414 N N . ALA D 4 91 ? -25.564 50.218 -15.677 1.00 24.80 ? 90 ALA L N 1 ATOM 6415 C CA . ALA D 4 91 ? -24.576 50.973 -14.871 1.00 26.40 ? 90 ALA L CA 1 ATOM 6416 C C . ALA D 4 91 ? -23.210 50.536 -15.287 1.00 31.84 ? 90 ALA L C 1 ATOM 6417 O O . ALA D 4 91 ? -23.066 49.462 -15.820 1.00 24.73 ? 90 ALA L O 1 ATOM 6418 C CB . ALA D 4 91 ? -24.774 50.692 -13.362 1.00 24.36 ? 90 ALA L CB 1 ATOM 6419 N N . TRP D 4 92 ? -22.187 51.345 -15.036 1.00 27.93 ? 91 TRP L N 1 ATOM 6420 C CA . TRP D 4 92 ? -20.831 50.845 -15.159 1.00 22.90 ? 91 TRP L CA 1 ATOM 6421 C C . TRP D 4 92 ? -20.511 49.893 -14.001 1.00 31.24 ? 91 TRP L C 1 ATOM 6422 O O . TRP D 4 92 ? -21.028 50.042 -12.893 1.00 32.70 ? 91 TRP L O 1 ATOM 6423 C CB . TRP D 4 92 ? -19.852 52.022 -15.140 1.00 21.43 ? 91 TRP L CB 1 ATOM 6424 C CG . TRP D 4 92 ? -18.455 51.642 -15.416 1.00 23.10 ? 91 TRP L CG 1 ATOM 6425 C CD1 . TRP D 4 92 ? -17.440 51.462 -14.467 1.00 26.30 ? 91 TRP L CD1 1 ATOM 6426 C CD2 . TRP D 4 92 ? -17.843 51.436 -16.695 1.00 22.28 ? 91 TRP L CD2 1 ATOM 6427 N NE1 . TRP D 4 92 ? -16.270 51.203 -15.111 1.00 25.49 ? 91 TRP L NE1 1 ATOM 6428 C CE2 . TRP D 4 92 ? -16.483 51.155 -16.473 1.00 25.29 ? 91 TRP L CE2 1 ATOM 6429 C CE3 . TRP D 4 92 ? -18.329 51.478 -18.027 1.00 24.41 ? 91 TRP L CE3 1 ATOM 6430 C CZ2 . TRP D 4 92 ? -15.593 50.872 -17.511 1.00 26.00 ? 91 TRP L CZ2 1 ATOM 6431 C CZ3 . TRP D 4 92 ? -17.459 51.232 -19.036 1.00 22.39 ? 91 TRP L CZ3 1 ATOM 6432 C CH2 . TRP D 4 92 ? -16.084 50.936 -18.787 1.00 29.68 ? 91 TRP L CH2 1 ATOM 6433 N N . ASP D 4 93 ? -19.722 48.875 -14.278 1.00 26.28 ? 92 ASP L N 1 ATOM 6434 C CA . ASP D 4 93 ? -19.272 47.939 -13.250 1.00 30.69 ? 92 ASP L CA 1 ATOM 6435 C C . ASP D 4 93 ? -17.757 48.032 -13.101 1.00 31.85 ? 92 ASP L C 1 ATOM 6436 O O . ASP D 4 93 ? -17.020 47.765 -14.038 1.00 28.17 ? 92 ASP L O 1 ATOM 6437 C CB . ASP D 4 93 ? -19.658 46.493 -13.611 1.00 25.68 ? 92 ASP L CB 1 ATOM 6438 C CG . ASP D 4 93 ? -19.361 45.508 -12.464 1.00 37.61 ? 92 ASP L CG 1 ATOM 6439 O OD1 . ASP D 4 93 ? -20.320 45.064 -11.802 1.00 37.23 ? 92 ASP L OD1 1 ATOM 6440 O OD2 . ASP D 4 93 ? -18.177 45.176 -12.245 1.00 31.37 ? 92 ASP L OD2 1 ATOM 6441 N N . ASP D 4 94 ? -17.296 48.405 -11.893 1.00 28.53 ? 93 ASP L N 1 ATOM 6442 C CA . ASP D 4 94 ? -15.877 48.587 -11.681 1.00 36.03 ? 93 ASP L CA 1 ATOM 6443 C C . ASP D 4 94 ? -15.073 47.295 -11.527 1.00 35.77 ? 93 ASP L C 1 ATOM 6444 O O . ASP D 4 94 ? -13.843 47.322 -11.519 1.00 41.84 ? 93 ASP L O 1 ATOM 6445 C CB . ASP D 4 94 ? -15.648 49.488 -10.471 1.00 35.66 ? 93 ASP L CB 1 ATOM 6446 C CG . ASP D 4 94 ? -15.970 50.936 -10.753 1.00 50.32 ? 93 ASP L CG 1 ATOM 6447 O OD1 . ASP D 4 94 ? -15.632 51.414 -11.859 1.00 47.52 ? 93 ASP L OD1 1 ATOM 6448 O OD2 . ASP D 4 94 ? -16.545 51.609 -9.864 1.00 61.78 ? 93 ASP L OD2 1 ATOM 6449 N N . SER D 4 95 ? -15.734 46.159 -11.417 1.00 33.69 ? 94 SER L N 1 ATOM 6450 C CA . SER D 4 95 ? -14.965 44.920 -11.367 1.00 35.99 ? 94 SER L CA 1 ATOM 6451 C C . SER D 4 95 ? -14.767 44.368 -12.748 1.00 40.84 ? 94 SER L C 1 ATOM 6452 O O . SER D 4 95 ? -13.681 43.912 -13.093 1.00 36.43 ? 94 SER L O 1 ATOM 6453 C CB . SER D 4 95 ? -15.665 43.874 -10.504 1.00 44.82 ? 94 SER L CB 1 ATOM 6454 O OG . SER D 4 95 ? -15.726 44.352 -9.184 1.00 54.94 ? 94 SER L OG 1 ATOM 6455 N N . LEU D 4 96 ? -15.825 44.415 -13.553 1.00 35.80 ? 95 LEU L N 1 ATOM 6456 C CA . LEU D 4 96 ? -15.714 43.987 -14.951 1.00 29.09 ? 95 LEU L CA 1 ATOM 6457 C C . LEU D 4 96 ? -15.038 45.034 -15.803 1.00 26.97 ? 95 LEU L C 1 ATOM 6458 O O . LEU D 4 96 ? -14.619 44.740 -16.915 1.00 31.16 ? 95 LEU L O 1 ATOM 6459 C CB . LEU D 4 96 ? -17.116 43.623 -15.530 1.00 20.00 ? 95 LEU L CB 1 ATOM 6460 C CG . LEU D 4 96 ? -17.924 42.492 -14.817 1.00 20.00 ? 95 LEU L CG 1 ATOM 6461 C CD1 . LEU D 4 96 ? -19.369 42.407 -15.395 1.00 20.00 ? 95 LEU L CD1 1 ATOM 6462 C CD2 . LEU D 4 96 ? -17.291 41.140 -14.904 1.00 20.00 ? 95 LEU L CD2 1 ATOM 6463 N N . LYS D 4 97 A -14.889 46.247 -15.270 1.00 25.02 ? 95 LYS L N 1 ATOM 6464 C CA . LYS D 4 97 A -14.423 47.394 -16.046 1.00 27.17 ? 95 LYS L CA 1 ATOM 6465 C C . LYS D 4 97 A -15.216 47.510 -17.351 1.00 27.15 ? 95 LYS L C 1 ATOM 6466 O O . LYS D 4 97 A -14.616 47.567 -18.441 1.00 25.82 ? 95 LYS L O 1 ATOM 6467 C CB . LYS D 4 97 A -12.919 47.318 -16.363 1.00 35.63 ? 95 LYS L CB 1 ATOM 6468 C CG . LYS D 4 97 A -12.003 47.749 -15.197 1.00 47.63 ? 95 LYS L CG 1 ATOM 6469 C CD . LYS D 4 97 A -12.047 46.803 -14.012 1.00 58.32 ? 95 LYS L CD 1 ATOM 6470 C CE . LYS D 4 97 A -11.079 47.265 -12.884 1.00 73.54 ? 95 LYS L CE 1 ATOM 6471 N NZ . LYS D 4 97 A -11.223 46.475 -11.607 1.00 71.26 ? 95 LYS L NZ 1 ATOM 6472 N N . GLY D 4 98 B -16.545 47.514 -17.242 1.00 23.31 ? 95 GLY L N 1 ATOM 6473 C CA . GLY D 4 98 B -17.360 47.617 -18.457 1.00 22.05 ? 95 GLY L CA 1 ATOM 6474 C C . GLY D 4 98 B -18.797 47.980 -18.133 1.00 21.46 ? 95 GLY L C 1 ATOM 6475 O O . GLY D 4 98 B -19.197 47.936 -16.981 1.00 23.69 ? 95 GLY L O 1 ATOM 6476 N N . ALA D 4 99 ? -19.580 48.363 -19.144 1.00 18.75 ? 96 ALA L N 1 ATOM 6477 C CA . ALA D 4 99 ? -20.918 48.711 -18.910 1.00 19.77 ? 96 ALA L CA 1 ATOM 6478 C C . ALA D 4 99 ? -21.754 47.417 -18.775 1.00 28.35 ? 96 ALA L C 1 ATOM 6479 O O . ALA D 4 99 ? -21.521 46.413 -19.496 1.00 26.29 ? 96 ALA L O 1 ATOM 6480 C CB . ALA D 4 99 ? -21.436 49.589 -20.076 1.00 21.44 ? 96 ALA L CB 1 ATOM 6481 N N . VAL D 4 100 ? -22.703 47.414 -17.850 1.00 21.58 ? 97 VAL L N 1 ATOM 6482 C CA . VAL D 4 100 ? -23.604 46.280 -17.700 1.00 20.74 ? 97 VAL L CA 1 ATOM 6483 C C . VAL D 4 100 ? -25.058 46.717 -17.785 1.00 22.19 ? 97 VAL L C 1 ATOM 6484 O O . VAL D 4 100 ? -25.384 47.897 -17.557 1.00 25.22 ? 97 VAL L O 1 ATOM 6485 C CB . VAL D 4 100 ? -23.357 45.474 -16.417 1.00 24.11 ? 97 VAL L CB 1 ATOM 6486 C CG1 . VAL D 4 100 ? -21.898 44.902 -16.390 1.00 26.57 ? 97 VAL L CG1 1 ATOM 6487 C CG2 . VAL D 4 100 ? -23.642 46.330 -15.203 1.00 27.01 ? 97 VAL L CG2 1 ATOM 6488 N N . PHE D 4 101 ? -25.920 45.748 -18.109 1.00 24.13 ? 98 PHE L N 1 ATOM 6489 C CA . PHE D 4 101 ? -27.351 45.976 -18.289 1.00 23.42 ? 98 PHE L CA 1 ATOM 6490 C C . PHE D 4 101 ? -28.138 44.952 -17.487 1.00 29.05 ? 98 PHE L C 1 ATOM 6491 O O . PHE D 4 101 ? -27.688 43.838 -17.293 1.00 27.74 ? 98 PHE L O 1 ATOM 6492 C CB . PHE D 4 101 ? -27.768 45.801 -19.796 1.00 22.99 ? 98 PHE L CB 1 ATOM 6493 C CG . PHE D 4 101 ? -27.274 46.855 -20.689 1.00 19.91 ? 98 PHE L CG 1 ATOM 6494 C CD1 . PHE D 4 101 ? -26.062 46.674 -21.403 1.00 20.99 ? 98 PHE L CD1 1 ATOM 6495 C CD2 . PHE D 4 101 ? -28.045 48.034 -20.900 1.00 21.30 ? 98 PHE L CD2 1 ATOM 6496 C CE1 . PHE D 4 101 ? -25.622 47.655 -22.259 1.00 25.54 ? 98 PHE L CE1 1 ATOM 6497 C CE2 . PHE D 4 101 ? -27.612 49.039 -21.726 1.00 23.96 ? 98 PHE L CE2 1 ATOM 6498 C CZ . PHE D 4 101 ? -26.372 48.834 -22.451 1.00 24.73 ? 98 PHE L CZ 1 ATOM 6499 N N . GLY D 4 102 ? -29.348 45.310 -17.044 1.00 25.52 ? 99 GLY L N 1 ATOM 6500 C CA . GLY D 4 102 ? -30.250 44.299 -16.552 1.00 22.78 ? 99 GLY L CA 1 ATOM 6501 C C . GLY D 4 102 ? -30.788 43.452 -17.690 1.00 23.62 ? 99 GLY L C 1 ATOM 6502 O O . GLY D 4 102 ? -30.626 43.797 -18.870 1.00 22.00 ? 99 GLY L O 1 ATOM 6503 N N . GLY D 4 103 ? -31.475 42.366 -17.343 1.00 22.71 ? 100 GLY L N 1 ATOM 6504 C CA . GLY D 4 103 ? -31.991 41.459 -18.349 1.00 26.51 ? 100 GLY L CA 1 ATOM 6505 C C . GLY D 4 103 ? -33.205 41.992 -19.098 1.00 23.94 ? 100 GLY L C 1 ATOM 6506 O O . GLY D 4 103 ? -33.587 41.443 -20.107 1.00 26.92 ? 100 GLY L O 1 ATOM 6507 N N . GLY D 4 104 ? -33.772 43.092 -18.621 1.00 23.98 ? 101 GLY L N 1 ATOM 6508 C CA . GLY D 4 104 ? -34.914 43.690 -19.290 1.00 21.29 ? 101 GLY L CA 1 ATOM 6509 C C . GLY D 4 104 ? -36.232 43.294 -18.584 1.00 24.94 ? 101 GLY L C 1 ATOM 6510 O O . GLY D 4 104 ? -36.387 42.175 -18.119 1.00 27.20 ? 101 GLY L O 1 ATOM 6511 N N . THR D 4 105 ? -37.165 44.238 -18.541 1.00 25.53 ? 102 THR L N 1 ATOM 6512 C CA . THR D 4 105 ? -38.539 43.999 -18.065 1.00 22.61 ? 102 THR L CA 1 ATOM 6513 C C . THR D 4 105 ? -39.559 44.353 -19.162 1.00 27.82 ? 102 THR L C 1 ATOM 6514 O O . THR D 4 105 ? -39.564 45.460 -19.680 1.00 26.41 ? 102 THR L O 1 ATOM 6515 C CB . THR D 4 105 ? -38.842 44.900 -16.844 1.00 25.27 ? 102 THR L CB 1 ATOM 6516 O OG1 . THR D 4 105 ? -37.897 44.622 -15.783 1.00 25.87 ? 102 THR L OG1 1 ATOM 6517 C CG2 . THR D 4 105 ? -40.303 44.638 -16.316 1.00 23.77 ? 102 THR L CG2 1 ATOM 6518 N N . GLN D 4 106 ? -40.425 43.415 -19.492 1.00 25.97 ? 103 GLN L N 1 ATOM 6519 C CA . GLN D 4 106 ? -41.501 43.665 -20.442 1.00 25.40 ? 103 GLN L CA 1 ATOM 6520 C C . GLN D 4 106 ? -42.682 44.254 -19.673 1.00 31.83 ? 103 GLN L C 1 ATOM 6521 O O . GLN D 4 106 ? -43.199 43.638 -18.737 1.00 27.65 ? 103 GLN L O 1 ATOM 6522 C CB . GLN D 4 106 ? -41.890 42.378 -21.179 1.00 31.60 ? 103 GLN L CB 1 ATOM 6523 C CG . GLN D 4 106 ? -43.035 42.573 -22.204 1.00 34.19 ? 103 GLN L CG 1 ATOM 6524 C CD . GLN D 4 106 ? -42.755 43.689 -23.258 1.00 53.71 ? 103 GLN L CD 1 ATOM 6525 O OE1 . GLN D 4 106 ? -41.632 43.772 -23.797 1.00 48.86 ? 103 GLN L OE1 1 ATOM 6526 N NE2 . GLN D 4 106 ? -43.782 44.556 -23.547 1.00 39.71 ? 103 GLN L NE2 1 ATOM 6527 N N . LEU D 4 107 ? -43.095 45.437 -20.070 1.00 26.23 ? 104 LEU L N 1 ATOM 6528 C CA . LEU D 4 107 ? -44.256 46.103 -19.422 1.00 27.29 ? 104 LEU L CA 1 ATOM 6529 C C . LEU D 4 107 ? -45.437 45.891 -20.293 1.00 32.24 ? 104 LEU L C 1 ATOM 6530 O O . LEU D 4 107 ? -45.397 46.191 -21.475 1.00 28.45 ? 104 LEU L O 1 ATOM 6531 C CB . LEU D 4 107 ? -43.989 47.593 -19.258 1.00 26.53 ? 104 LEU L CB 1 ATOM 6532 C CG . LEU D 4 107 ? -45.081 48.375 -18.486 1.00 27.46 ? 104 LEU L CG 1 ATOM 6533 C CD1 . LEU D 4 107 ? -44.466 49.521 -17.817 1.00 37.67 ? 104 LEU L CD1 1 ATOM 6534 C CD2 . LEU D 4 107 ? -46.209 48.877 -19.405 1.00 32.48 ? 104 LEU L CD2 1 ATOM 6535 N N . THR D 4 108 ? -46.528 45.368 -19.730 1.00 25.58 ? 105 THR L N 1 ATOM 6536 C CA . THR D 4 108 ? -47.747 45.177 -20.502 1.00 27.36 ? 105 THR L CA 1 ATOM 6537 C C . THR D 4 108 ? -48.799 46.163 -19.998 1.00 30.00 ? 105 THR L C 1 ATOM 6538 O O . THR D 4 108 ? -48.931 46.330 -18.768 1.00 30.65 ? 105 THR L O 1 ATOM 6539 C CB . THR D 4 108 ? -48.254 43.727 -20.322 1.00 33.27 ? 105 THR L CB 1 ATOM 6540 O OG1 . THR D 4 108 ? -47.369 42.809 -20.989 1.00 33.32 ? 105 THR L OG1 1 ATOM 6541 C CG2 . THR D 4 108 ? -49.704 43.552 -20.893 1.00 34.66 ? 105 THR L CG2 1 ATOM 6542 N N . VAL D 4 109 ? -49.503 46.859 -20.893 1.00 30.26 ? 106 VAL L N 1 ATOM 6543 C CA . VAL D 4 109 ? -50.570 47.747 -20.415 1.00 26.93 ? 106 VAL L CA 1 ATOM 6544 C C . VAL D 4 109 ? -51.827 46.919 -20.502 1.00 29.93 ? 106 VAL L C 1 ATOM 6545 O O . VAL D 4 109 ? -52.205 46.444 -21.576 1.00 29.65 ? 106 VAL L O 1 ATOM 6546 C CB . VAL D 4 109 ? -50.689 49.041 -21.184 1.00 37.21 ? 106 VAL L CB 1 ATOM 6547 C CG1 . VAL D 4 109 ? -51.957 49.838 -20.734 1.00 34.17 ? 106 VAL L CG1 1 ATOM 6548 C CG2 . VAL D 4 109 ? -49.463 49.899 -20.921 1.00 28.78 ? 106 VAL L CG2 1 ATOM 6549 N N . LEU D 4 110 A -52.458 46.699 -19.348 1.00 31.26 ? 106 LEU L N 1 ATOM 6550 C CA . LEU D 4 110 A -53.631 45.839 -19.317 1.00 26.59 ? 106 LEU L CA 1 ATOM 6551 C C . LEU D 4 110 A -54.853 46.525 -19.930 1.00 24.35 ? 106 LEU L C 1 ATOM 6552 O O . LEU D 4 110 A -54.942 47.778 -19.999 1.00 31.25 ? 106 LEU L O 1 ATOM 6553 C CB . LEU D 4 110 A -53.913 45.407 -17.855 1.00 28.80 ? 106 LEU L CB 1 ATOM 6554 C CG . LEU D 4 110 A -52.819 44.613 -17.118 1.00 30.46 ? 106 LEU L CG 1 ATOM 6555 C CD1 . LEU D 4 110 A -53.121 44.528 -15.594 1.00 31.13 ? 106 LEU L CD1 1 ATOM 6556 C CD2 . LEU D 4 110 A -52.673 43.221 -17.738 1.00 25.38 ? 106 LEU L CD2 1 ATOM 6557 N N . GLY D 4 111 ? -55.831 45.704 -20.320 1.00 29.96 ? 107 GLY L N 1 ATOM 6558 C CA . GLY D 4 111 ? -57.123 46.238 -20.720 1.00 37.44 ? 107 GLY L CA 1 ATOM 6559 C C . GLY D 4 111 ? -57.496 46.088 -22.177 1.00 39.32 ? 107 GLY L C 1 ATOM 6560 O O . GLY D 4 111 ? -58.607 46.464 -22.605 1.00 38.66 ? 107 GLY L O 1 ATOM 6561 N N . GLN D 4 112 ? -56.565 45.556 -22.963 1.00 37.21 ? 108 GLN L N 1 ATOM 6562 C CA . GLN D 4 112 ? -56.826 45.398 -24.391 1.00 38.59 ? 108 GLN L CA 1 ATOM 6563 C C . GLN D 4 112 ? -57.689 44.161 -24.588 1.00 36.45 ? 108 GLN L C 1 ATOM 6564 O O . GLN D 4 112 ? -57.477 43.105 -23.946 1.00 36.10 ? 108 GLN L O 1 ATOM 6565 C CB . GLN D 4 112 ? -55.512 45.331 -25.183 1.00 43.29 ? 108 GLN L CB 1 ATOM 6566 C CG . GLN D 4 112 ? -54.568 46.529 -24.892 1.00 42.50 ? 108 GLN L CG 1 ATOM 6567 C CD . GLN D 4 112 ? -53.144 46.304 -25.424 1.00 53.31 ? 108 GLN L CD 1 ATOM 6568 O OE1 . GLN D 4 112 ? -52.140 46.559 -24.727 1.00 44.83 ? 108 GLN L OE1 1 ATOM 6569 N NE2 . GLN D 4 112 ? -53.055 45.828 -26.663 1.00 42.83 ? 108 GLN L NE2 1 ATOM 6570 N N . PRO D 4 113 ? -58.689 44.289 -25.462 1.00 50.80 ? 109 PRO L N 1 ATOM 6571 C CA . PRO D 4 113 ? -59.690 43.241 -25.700 1.00 53.67 ? 109 PRO L CA 1 ATOM 6572 C C . PRO D 4 113 ? -59.112 41.973 -26.308 1.00 52.79 ? 109 PRO L C 1 ATOM 6573 O O . PRO D 4 113 ? -58.312 42.070 -27.236 1.00 48.56 ? 109 PRO L O 1 ATOM 6574 C CB . PRO D 4 113 ? -60.646 43.898 -26.700 1.00 51.75 ? 109 PRO L CB 1 ATOM 6575 C CG . PRO D 4 113 ? -59.879 45.017 -27.320 1.00 55.99 ? 109 PRO L CG 1 ATOM 6576 C CD . PRO D 4 113 ? -58.940 45.505 -26.253 1.00 50.91 ? 109 PRO L CD 1 ATOM 6577 N N . LYS D 4 114 ? -59.514 40.811 -25.797 1.00 47.92 ? 110 LYS L N 1 ATOM 6578 C CA . LYS D 4 114 ? -59.156 39.542 -26.426 1.00 58.09 ? 110 LYS L CA 1 ATOM 6579 C C . LYS D 4 114 ? -59.671 39.466 -27.858 1.00 60.48 ? 110 LYS L C 1 ATOM 6580 O O . LYS D 4 114 ? -60.735 39.994 -28.181 1.00 53.61 ? 110 LYS L O 1 ATOM 6581 C CB . LYS D 4 114 ? -59.693 38.351 -25.635 1.00 67.07 ? 110 LYS L CB 1 ATOM 6582 C CG . LYS D 4 114 ? -58.723 37.780 -24.614 1.00 73.41 ? 110 LYS L CG 1 ATOM 6583 C CD . LYS D 4 114 ? -58.626 38.658 -23.362 1.00 82.93 ? 110 LYS L CD 1 ATOM 6584 C CE . LYS D 4 114 ? -57.818 37.966 -22.263 1.00 84.21 ? 110 LYS L CE 1 ATOM 6585 N NZ . LYS D 4 114 ? -57.681 38.804 -21.032 1.00 81.83 ? 110 LYS L NZ 1 ATOM 6586 N N . ALA D 4 115 ? -58.897 38.826 -28.726 1.00 54.12 ? 111 ALA L N 1 ATOM 6587 C CA . ALA D 4 115 ? -59.322 38.617 -30.105 1.00 47.85 ? 111 ALA L CA 1 ATOM 6588 C C . ALA D 4 115 ? -58.944 37.203 -30.525 1.00 58.44 ? 111 ALA L C 1 ATOM 6589 O O . ALA D 4 115 ? -57.781 36.804 -30.408 1.00 53.27 ? 111 ALA L O 1 ATOM 6590 C CB . ALA D 4 115 ? -58.714 39.678 -31.069 1.00 46.51 ? 111 ALA L CB 1 ATOM 6591 N N . ALA D 4 116 ? -59.933 36.434 -30.990 1.00 55.84 ? 112 ALA L N 1 ATOM 6592 C CA . ALA D 4 116 ? -59.697 35.048 -31.367 1.00 59.41 ? 112 ALA L CA 1 ATOM 6593 C C . ALA D 4 116 ? -59.007 34.981 -32.729 1.00 46.94 ? 112 ALA L C 1 ATOM 6594 O O . ALA D 4 116 ? -59.205 35.867 -33.575 1.00 53.04 ? 112 ALA L O 1 ATOM 6595 C CB . ALA D 4 116 ? -61.020 34.255 -31.380 1.00 59.83 ? 112 ALA L CB 1 ATOM 6596 N N . PRO D 4 117 ? -58.190 33.929 -32.937 1.00 46.83 ? 113 PRO L N 1 ATOM 6597 C CA . PRO D 4 117 ? -57.462 33.754 -34.211 1.00 57.85 ? 113 PRO L CA 1 ATOM 6598 C C . PRO D 4 117 ? -58.340 33.385 -35.419 1.00 59.53 ? 113 PRO L C 1 ATOM 6599 O O . PRO D 4 117 ? -59.105 32.420 -35.334 1.00 59.74 ? 113 PRO L O 1 ATOM 6600 C CB . PRO D 4 117 ? -56.505 32.588 -33.912 1.00 53.76 ? 113 PRO L CB 1 ATOM 6601 C CG . PRO D 4 117 ? -57.121 31.849 -32.747 1.00 50.71 ? 113 PRO L CG 1 ATOM 6602 C CD . PRO D 4 117 ? -57.821 32.908 -31.933 1.00 45.38 ? 113 PRO L CD 1 ATOM 6603 N N . SER D 4 118 ? -58.227 34.150 -36.509 1.00 57.57 ? 114 SER L N 1 ATOM 6604 C CA . SER D 4 118 ? -58.669 33.709 -37.842 1.00 56.74 ? 114 SER L CA 1 ATOM 6605 C C . SER D 4 118 ? -57.701 32.626 -38.356 1.00 64.08 ? 114 SER L C 1 ATOM 6606 O O . SER D 4 118 ? -56.487 32.836 -38.377 1.00 59.98 ? 114 SER L O 1 ATOM 6607 C CB . SER D 4 118 ? -58.657 34.882 -38.838 1.00 56.16 ? 114 SER L CB 1 ATOM 6608 O OG . SER D 4 118 ? -59.490 35.967 -38.443 1.00 65.67 ? 114 SER L OG 1 ATOM 6609 N N . VAL D 4 119 ? -58.215 31.474 -38.776 1.00 56.84 ? 115 VAL L N 1 ATOM 6610 C CA . VAL D 4 119 ? -57.350 30.462 -39.376 1.00 51.53 ? 115 VAL L CA 1 ATOM 6611 C C . VAL D 4 119 ? -57.694 30.208 -40.854 1.00 67.68 ? 115 VAL L C 1 ATOM 6612 O O . VAL D 4 119 ? -58.866 30.234 -41.237 1.00 65.69 ? 115 VAL L O 1 ATOM 6613 C CB . VAL D 4 119 ? -57.413 29.143 -38.601 1.00 50.36 ? 115 VAL L CB 1 ATOM 6614 C CG1 . VAL D 4 119 ? -56.342 28.191 -39.092 1.00 45.70 ? 115 VAL L CG1 1 ATOM 6615 C CG2 . VAL D 4 119 ? -57.274 29.408 -37.112 1.00 57.24 ? 115 VAL L CG2 1 ATOM 6616 N N . THR D 4 120 ? -56.662 30.006 -41.680 1.00 60.02 ? 116 THR L N 1 ATOM 6617 C CA . THR D 4 120 ? -56.806 29.532 -43.061 1.00 51.04 ? 116 THR L CA 1 ATOM 6618 C C . THR D 4 120 ? -55.854 28.355 -43.247 1.00 59.85 ? 116 THR L C 1 ATOM 6619 O O . THR D 4 120 ? -54.684 28.423 -42.858 1.00 56.49 ? 116 THR L O 1 ATOM 6620 C CB . THR D 4 120 ? -56.481 30.628 -44.120 1.00 48.91 ? 116 THR L CB 1 ATOM 6621 O OG1 . THR D 4 120 ? -57.383 31.737 -43.994 1.00 60.54 ? 116 THR L OG1 1 ATOM 6622 C CG2 . THR D 4 120 ? -56.603 30.057 -45.525 1.00 55.15 ? 116 THR L CG2 1 ATOM 6623 N N . LEU D 4 121 ? -56.354 27.260 -43.808 1.00 49.99 ? 117 LEU L N 1 ATOM 6624 C CA . LEU D 4 121 ? -55.511 26.090 -44.038 1.00 50.80 ? 117 LEU L CA 1 ATOM 6625 C C . LEU D 4 121 ? -55.519 25.682 -45.516 1.00 67.00 ? 117 LEU L C 1 ATOM 6626 O O . LEU D 4 121 ? -56.567 25.339 -46.081 1.00 62.20 ? 117 LEU L O 1 ATOM 6627 C CB . LEU D 4 121 ? -55.907 24.922 -43.124 1.00 56.06 ? 117 LEU L CB 1 ATOM 6628 C CG . LEU D 4 121 ? -55.170 23.597 -43.353 1.00 63.81 ? 117 LEU L CG 1 ATOM 6629 C CD1 . LEU D 4 121 ? -53.691 23.711 -43.059 1.00 59.39 ? 117 LEU L CD1 1 ATOM 6630 C CD2 . LEU D 4 121 ? -55.786 22.524 -42.490 1.00 65.62 ? 117 LEU L CD2 1 ATOM 6631 N N . PHE D 4 122 ? -54.352 25.754 -46.147 1.00 57.59 ? 118 PHE L N 1 ATOM 6632 C CA . PHE D 4 122 ? -54.229 25.364 -47.543 1.00 53.69 ? 118 PHE L CA 1 ATOM 6633 C C . PHE D 4 122 ? -53.660 23.951 -47.651 1.00 62.73 ? 118 PHE L C 1 ATOM 6634 O O . PHE D 4 122 ? -52.712 23.592 -46.946 1.00 54.99 ? 118 PHE L O 1 ATOM 6635 C CB . PHE D 4 122 ? -53.344 26.339 -48.312 1.00 48.30 ? 118 PHE L CB 1 ATOM 6636 C CG . PHE D 4 122 ? -53.973 27.694 -48.563 1.00 60.59 ? 118 PHE L CG 1 ATOM 6637 C CD1 . PHE D 4 122 ? -54.876 27.879 -49.601 1.00 56.98 ? 118 PHE L CD1 1 ATOM 6638 C CD2 . PHE D 4 122 ? -53.615 28.799 -47.802 1.00 59.36 ? 118 PHE L CD2 1 ATOM 6639 C CE1 . PHE D 4 122 ? -55.438 29.136 -49.857 1.00 56.61 ? 118 PHE L CE1 1 ATOM 6640 C CE2 . PHE D 4 122 ? -54.163 30.061 -48.057 1.00 51.50 ? 118 PHE L CE2 1 ATOM 6641 C CZ . PHE D 4 122 ? -55.069 30.230 -49.091 1.00 61.71 ? 118 PHE L CZ 1 ATOM 6642 N N . PRO D 4 123 ? -54.260 23.127 -48.527 1.00 59.65 ? 119 PRO L N 1 ATOM 6643 C CA . PRO D 4 123 ? -53.732 21.783 -48.795 1.00 61.67 ? 119 PRO L CA 1 ATOM 6644 C C . PRO D 4 123 ? -52.574 21.897 -49.782 1.00 56.61 ? 119 PRO L C 1 ATOM 6645 O O . PRO D 4 123 ? -52.436 22.963 -50.417 1.00 55.26 ? 119 PRO L O 1 ATOM 6646 C CB . PRO D 4 123 ? -54.915 21.079 -49.470 1.00 57.42 ? 119 PRO L CB 1 ATOM 6647 C CG . PRO D 4 123 ? -55.626 22.209 -50.210 1.00 63.04 ? 119 PRO L CG 1 ATOM 6648 C CD . PRO D 4 123 ? -55.466 23.433 -49.325 1.00 61.28 ? 119 PRO L CD 1 ATOM 6649 N N . PRO D 4 124 ? -51.775 20.821 -49.929 1.00 60.60 ? 120 PRO L N 1 ATOM 6650 C CA . PRO D 4 124 ? -50.688 20.774 -50.918 1.00 58.88 ? 120 PRO L CA 1 ATOM 6651 C C . PRO D 4 124 ? -51.189 21.109 -52.319 1.00 58.51 ? 120 PRO L C 1 ATOM 6652 O O . PRO D 4 124 ? -52.273 20.651 -52.712 1.00 59.38 ? 120 PRO L O 1 ATOM 6653 C CB . PRO D 4 124 ? -50.229 19.315 -50.866 1.00 52.01 ? 120 PRO L CB 1 ATOM 6654 C CG . PRO D 4 124 ? -50.599 18.843 -49.513 1.00 60.58 ? 120 PRO L CG 1 ATOM 6655 C CD . PRO D 4 124 ? -51.813 19.610 -49.087 1.00 60.68 ? 120 PRO L CD 1 ATOM 6656 N N . SER D 4 125 ? -50.432 21.919 -53.052 1.00 49.06 ? 121 SER L N 1 ATOM 6657 C CA . SER D 4 125 ? -50.793 22.249 -54.427 1.00 57.55 ? 121 SER L CA 1 ATOM 6658 C C . SER D 4 125 ? -50.414 21.073 -55.351 1.00 51.18 ? 121 SER L C 1 ATOM 6659 O O . SER D 4 125 ? -49.560 20.232 -55.017 1.00 55.16 ? 121 SER L O 1 ATOM 6660 C CB . SER D 4 125 ? -50.133 23.560 -54.893 1.00 53.82 ? 121 SER L CB 1 ATOM 6661 O OG . SER D 4 125 ? -48.725 23.412 -55.001 1.00 65.53 ? 121 SER L OG 1 ATOM 6662 N N . SER D 4 126 ? -51.063 21.009 -56.507 1.00 58.15 ? 122 SER L N 1 ATOM 6663 C CA . SER D 4 126 ? -50.809 19.907 -57.420 1.00 63.93 ? 122 SER L CA 1 ATOM 6664 C C . SER D 4 126 ? -49.367 19.968 -57.926 1.00 65.48 ? 122 SER L C 1 ATOM 6665 O O . SER D 4 126 ? -48.669 18.949 -57.980 1.00 66.46 ? 122 SER L O 1 ATOM 6666 C CB . SER D 4 126 ? -51.797 19.940 -58.586 1.00 67.31 ? 122 SER L CB 1 ATOM 6667 O OG . SER D 4 126 ? -51.615 21.112 -59.363 1.00 76.96 ? 122 SER L OG 1 ATOM 6668 N N . GLU D 4 127 ? -48.928 21.171 -58.281 1.00 64.09 ? 123 GLU L N 1 ATOM 6669 C CA . GLU D 4 127 ? -47.552 21.399 -58.710 1.00 69.25 ? 123 GLU L CA 1 ATOM 6670 C C . GLU D 4 127 ? -46.558 20.749 -57.749 1.00 70.05 ? 123 GLU L C 1 ATOM 6671 O O . GLU D 4 127 ? -45.610 20.082 -58.171 1.00 75.60 ? 123 GLU L O 1 ATOM 6672 C CB . GLU D 4 127 ? -47.256 22.903 -58.826 1.00 66.22 ? 123 GLU L CB 1 ATOM 6673 C CG . GLU D 4 127 ? -48.124 23.662 -59.835 1.00 81.24 ? 123 GLU L CG 1 ATOM 6674 C CD . GLU D 4 127 ? -49.567 23.912 -59.365 1.00 81.99 ? 123 GLU L CD 1 ATOM 6675 O OE1 . GLU D 4 127 ? -50.042 23.258 -58.401 1.00 76.34 ? 123 GLU L OE1 1 ATOM 6676 O OE2 . GLU D 4 127 ? -50.234 24.777 -59.974 1.00 86.91 ? 123 GLU L OE2 1 ATOM 6677 N N . GLU D 4 128 ? -46.798 20.921 -56.454 1.00 61.80 ? 124 GLU L N 1 ATOM 6678 C CA . GLU D 4 128 ? -45.843 20.475 -55.447 1.00 61.97 ? 124 GLU L CA 1 ATOM 6679 C C . GLU D 4 128 ? -45.823 18.951 -55.316 1.00 64.08 ? 124 GLU L C 1 ATOM 6680 O O . GLU D 4 128 ? -44.770 18.347 -55.097 1.00 64.97 ? 124 GLU L O 1 ATOM 6681 C CB . GLU D 4 128 ? -46.133 21.126 -54.089 1.00 61.62 ? 124 GLU L CB 1 ATOM 6682 C CG . GLU D 4 128 ? -45.205 20.650 -52.992 1.00 51.31 ? 124 GLU L CG 1 ATOM 6683 C CD . GLU D 4 128 ? -45.523 21.239 -51.613 1.00 62.22 ? 124 GLU L CD 1 ATOM 6684 O OE1 . GLU D 4 128 ? -46.668 21.712 -51.379 1.00 58.11 ? 124 GLU L OE1 1 ATOM 6685 O OE2 . GLU D 4 128 ? -44.606 21.224 -50.758 1.00 53.40 ? 124 GLU L OE2 1 ATOM 6686 N N . LEU D 4 129 ? -46.996 18.341 -55.433 1.00 69.16 ? 125 LEU L N 1 ATOM 6687 C CA . LEU D 4 129 ? -47.102 16.884 -55.439 1.00 69.65 ? 125 LEU L CA 1 ATOM 6688 C C . LEU D 4 129 ? -46.265 16.290 -56.584 1.00 64.38 ? 125 LEU L C 1 ATOM 6689 O O . LEU D 4 129 ? -45.537 15.304 -56.388 1.00 63.29 ? 125 LEU L O 1 ATOM 6690 C CB . LEU D 4 129 ? -48.570 16.472 -55.555 1.00 65.71 ? 125 LEU L CB 1 ATOM 6691 C CG . LEU D 4 129 ? -49.410 16.908 -54.360 1.00 68.14 ? 125 LEU L CG 1 ATOM 6692 C CD1 . LEU D 4 129 ? -50.879 16.718 -54.661 1.00 69.13 ? 125 LEU L CD1 1 ATOM 6693 C CD2 . LEU D 4 129 ? -49.006 16.115 -53.125 1.00 59.84 ? 125 LEU L CD2 1 ATOM 6694 N N . GLN D 4 130 ? -46.351 16.933 -57.753 1.00 69.05 ? 126 GLN L N 1 ATOM 6695 C CA . GLN D 4 130 ? -45.566 16.564 -58.934 1.00 69.14 ? 126 GLN L CA 1 ATOM 6696 C C . GLN D 4 130 ? -44.071 16.654 -58.675 1.00 79.42 ? 126 GLN L C 1 ATOM 6697 O O . GLN D 4 130 ? -43.277 15.927 -59.278 1.00 74.17 ? 126 GLN L O 1 ATOM 6698 C CB . GLN D 4 130 ? -45.905 17.477 -60.105 1.00 73.67 ? 126 GLN L CB 1 ATOM 6699 C CG . GLN D 4 130 ? -47.342 17.409 -60.570 1.00 84.40 ? 126 GLN L CG 1 ATOM 6700 C CD . GLN D 4 130 ? -47.600 18.284 -61.792 1.00 107.85 ? 126 GLN L CD 1 ATOM 6701 O OE1 . GLN D 4 130 ? -46.694 18.956 -62.299 1.00 110.83 ? 126 GLN L OE1 1 ATOM 6702 N NE2 . GLN D 4 130 ? -48.841 18.280 -62.268 1.00 112.83 ? 126 GLN L NE2 1 ATOM 6703 N N . ALA D 4 131 ? -43.683 17.565 -57.790 1.00 73.41 ? 127 ALA L N 1 ATOM 6704 C CA . ALA D 4 131 ? -42.286 17.672 -57.408 1.00 71.91 ? 127 ALA L CA 1 ATOM 6705 C C . ALA D 4 131 ? -42.005 16.759 -56.221 1.00 71.25 ? 127 ALA L C 1 ATOM 6706 O O . ALA D 4 131 ? -40.979 16.891 -55.557 1.00 71.34 ? 127 ALA L O 1 ATOM 6707 C CB . ALA D 4 131 ? -41.924 19.115 -57.090 1.00 71.01 ? 127 ALA L CB 1 ATOM 6708 N N . ASN D 4 132 ? -42.933 15.840 -55.962 1.00 66.24 ? 128 ASN L N 1 ATOM 6709 C CA . ASN D 4 132 ? -42.762 14.802 -54.950 1.00 69.47 ? 128 ASN L CA 1 ATOM 6710 C C . ASN D 4 132 ? -42.600 15.308 -53.523 1.00 67.75 ? 128 ASN L C 1 ATOM 6711 O O . ASN D 4 132 ? -41.952 14.661 -52.693 1.00 62.75 ? 128 ASN L O 1 ATOM 6712 C CB . ASN D 4 132 ? -41.600 13.871 -55.305 1.00 78.09 ? 128 ASN L CB 1 ATOM 6713 C CG . ASN D 4 132 ? -41.832 12.449 -54.816 1.00 89.54 ? 128 ASN L CG 1 ATOM 6714 O OD1 . ASN D 4 132 ? -42.873 11.852 -55.101 1.00 84.95 ? 128 ASN L OD1 1 ATOM 6715 N ND2 . ASN D 4 132 ? -40.874 11.906 -54.061 1.00 82.79 ? 128 ASN L ND2 1 ATOM 6716 N N . LYS D 4 133 ? -43.195 16.466 -53.247 1.00 72.41 ? 129 LYS L N 1 ATOM 6717 C CA . LYS D 4 133 ? -43.293 17.006 -51.888 1.00 68.77 ? 129 LYS L CA 1 ATOM 6718 C C . LYS D 4 133 ? -44.755 17.363 -51.593 1.00 64.61 ? 129 LYS L C 1 ATOM 6719 O O . LYS D 4 133 ? -45.557 17.535 -52.513 1.00 68.52 ? 129 LYS L O 1 ATOM 6720 C CB . LYS D 4 133 ? -42.412 18.266 -51.720 1.00 64.94 ? 129 LYS L CB 1 ATOM 6721 C CG . LYS D 4 133 ? -40.899 18.063 -51.875 1.00 66.65 ? 129 LYS L CG 1 ATOM 6722 C CD . LYS D 4 133 ? -40.304 17.305 -50.689 1.00 68.00 ? 129 LYS L CD 1 ATOM 6723 C CE . LYS D 4 133 ? -38.857 16.904 -50.962 1.00 81.18 ? 129 LYS L CE 1 ATOM 6724 N NZ . LYS D 4 133 ? -38.367 15.883 -49.985 1.00 85.79 ? 129 LYS L NZ 1 ATOM 6725 N N . ALA D 4 134 ? -45.100 17.470 -50.315 1.00 64.20 ? 130 ALA L N 1 ATOM 6726 C CA . ALA D 4 134 ? -46.405 17.997 -49.928 1.00 62.43 ? 130 ALA L CA 1 ATOM 6727 C C . ALA D 4 134 ? -46.324 18.889 -48.677 1.00 60.95 ? 130 ALA L C 1 ATOM 6728 O O . ALA D 4 134 ? -45.803 18.471 -47.627 1.00 52.97 ? 130 ALA L O 1 ATOM 6729 C CB . ALA D 4 134 ? -47.402 16.869 -49.712 1.00 58.69 ? 130 ALA L CB 1 ATOM 6730 N N . THR D 4 135 ? -46.857 20.107 -48.786 1.00 46.77 ? 131 THR L N 1 ATOM 6731 C CA . THR D 4 135 ? -46.866 21.015 -47.630 1.00 59.77 ? 131 THR L CA 1 ATOM 6732 C C . THR D 4 135 ? -48.242 21.529 -47.239 1.00 54.80 ? 131 THR L C 1 ATOM 6733 O O . THR D 4 135 ? -48.943 22.165 -48.047 1.00 55.27 ? 131 THR L O 1 ATOM 6734 C CB . THR D 4 135 ? -45.976 22.266 -47.843 1.00 49.20 ? 131 THR L CB 1 ATOM 6735 O OG1 . THR D 4 135 ? -44.707 21.879 -48.377 1.00 48.12 ? 131 THR L OG1 1 ATOM 6736 C CG2 . THR D 4 135 ? -45.757 22.963 -46.503 1.00 48.31 ? 131 THR L CG2 1 ATOM 6737 N N . LEU D 4 136 ? -48.607 21.287 -45.980 1.00 52.56 ? 132 LEU L N 1 ATOM 6738 C CA . LEU D 4 136 ? -49.806 21.888 -45.412 1.00 62.40 ? 132 LEU L CA 1 ATOM 6739 C C . LEU D 4 136 ? -49.492 23.203 -44.712 1.00 58.19 ? 132 LEU L C 1 ATOM 6740 O O . LEU D 4 136 ? -48.663 23.247 -43.790 1.00 55.90 ? 132 LEU L O 1 ATOM 6741 C CB . LEU D 4 136 ? -50.520 20.920 -44.470 1.00 63.87 ? 132 LEU L CB 1 ATOM 6742 C CG . LEU D 4 136 ? -51.221 19.825 -45.282 1.00 64.02 ? 132 LEU L CG 1 ATOM 6743 C CD1 . LEU D 4 136 ? -50.490 18.511 -45.114 1.00 74.74 ? 132 LEU L CD1 1 ATOM 6744 C CD2 . LEU D 4 136 ? -52.681 19.687 -44.883 1.00 76.86 ? 132 LEU L CD2 1 ATOM 6745 N N . VAL D 4 137 ? -50.186 24.249 -45.162 1.00 45.88 ? 133 VAL L N 1 ATOM 6746 C CA . VAL D 4 137 ? -49.928 25.627 -44.761 1.00 51.69 ? 133 VAL L CA 1 ATOM 6747 C C . VAL D 4 137 ? -51.079 26.179 -43.909 1.00 52.12 ? 133 VAL L C 1 ATOM 6748 O O . VAL D 4 137 ? -52.190 26.384 -44.406 1.00 50.95 ? 133 VAL L O 1 ATOM 6749 C CB . VAL D 4 137 ? -49.698 26.549 -45.996 1.00 46.84 ? 133 VAL L CB 1 ATOM 6750 C CG1 . VAL D 4 137 ? -49.489 27.999 -45.557 1.00 48.22 ? 133 VAL L CG1 1 ATOM 6751 C CG2 . VAL D 4 137 ? -48.501 26.078 -46.818 1.00 40.26 ? 133 VAL L CG2 1 ATOM 6752 N N . CYS D 4 138 ? -50.801 26.411 -42.625 1.00 54.55 ? 134 CYS L N 1 ATOM 6753 C CA . CYS D 4 138 ? -51.801 26.911 -41.686 1.00 50.36 ? 134 CYS L CA 1 ATOM 6754 C C . CYS D 4 138 ? -51.469 28.341 -41.272 1.00 50.86 ? 134 CYS L C 1 ATOM 6755 O O . CYS D 4 138 ? -50.469 28.584 -40.583 1.00 50.15 ? 134 CYS L O 1 ATOM 6756 C CB . CYS D 4 138 ? -51.851 26.012 -40.455 1.00 55.90 ? 134 CYS L CB 1 ATOM 6757 S SG . CYS D 4 138 ? -53.279 26.314 -39.369 1.00 65.57 ? 134 CYS L SG 1 ATOM 6758 N N . LEU D 4 139 ? -52.299 29.278 -41.706 1.00 44.31 ? 135 LEU L N 1 ATOM 6759 C CA . LEU D 4 139 ? -52.078 30.692 -41.455 1.00 47.57 ? 135 LEU L CA 1 ATOM 6760 C C . LEU D 4 139 ? -52.969 31.291 -40.355 1.00 55.89 ? 135 LEU L C 1 ATOM 6761 O O . LEU D 4 139 ? -54.193 31.380 -40.501 1.00 52.53 ? 135 LEU L O 1 ATOM 6762 C CB . LEU D 4 139 ? -52.276 31.472 -42.754 1.00 42.71 ? 135 LEU L CB 1 ATOM 6763 C CG . LEU D 4 139 ? -51.331 31.055 -43.879 1.00 53.56 ? 135 LEU L CG 1 ATOM 6764 C CD1 . LEU D 4 139 ? -51.620 31.856 -45.156 1.00 54.83 ? 135 LEU L CD1 1 ATOM 6765 C CD2 . LEU D 4 139 ? -49.894 31.271 -43.420 1.00 49.18 ? 135 LEU L CD2 1 ATOM 6766 N N . ILE D 4 140 ? -52.344 31.751 -39.272 1.00 50.58 ? 136 ILE L N 1 ATOM 6767 C CA . ILE D 4 140 ? -53.083 32.242 -38.111 1.00 44.92 ? 136 ILE L CA 1 ATOM 6768 C C . ILE D 4 140 ? -52.960 33.745 -37.962 1.00 54.09 ? 136 ILE L C 1 ATOM 6769 O O . ILE D 4 140 ? -51.848 34.284 -37.972 1.00 44.21 ? 136 ILE L O 1 ATOM 6770 C CB . ILE D 4 140 ? -52.549 31.583 -36.889 1.00 50.65 ? 136 ILE L CB 1 ATOM 6771 C CG1 . ILE D 4 140 ? -52.398 30.090 -37.193 1.00 41.11 ? 136 ILE L CG1 1 ATOM 6772 C CG2 . ILE D 4 140 ? -53.435 31.932 -35.691 1.00 46.56 ? 136 ILE L CG2 1 ATOM 6773 C CD1 . ILE D 4 140 ? -51.512 29.334 -36.229 1.00 43.11 ? 136 ILE L CD1 1 ATOM 6774 N N . SER D 4 141 ? -54.086 34.447 -37.834 1.00 45.35 ? 137 SER L N 1 ATOM 6775 C CA . SER D 4 141 ? -54.013 35.899 -37.836 1.00 45.09 ? 137 SER L CA 1 ATOM 6776 C C . SER D 4 141 ? -54.976 36.548 -36.852 1.00 49.36 ? 137 SER L C 1 ATOM 6777 O O . SER D 4 141 ? -55.882 35.898 -36.354 1.00 45.03 ? 137 SER L O 1 ATOM 6778 C CB . SER D 4 141 ? -54.224 36.446 -39.250 1.00 52.26 ? 137 SER L CB 1 ATOM 6779 O OG . SER D 4 141 ? -55.441 35.973 -39.796 1.00 54.33 ? 137 SER L OG 1 ATOM 6780 N N . ASP D 4 142 ? -54.745 37.824 -36.566 1.00 46.88 ? 138 ASP L N 1 ATOM 6781 C CA . ASP D 4 142 ? -55.665 38.606 -35.740 1.00 61.69 ? 138 ASP L CA 1 ATOM 6782 C C . ASP D 4 142 ? -55.997 38.037 -34.357 1.00 57.90 ? 138 ASP L C 1 ATOM 6783 O O . ASP D 4 142 ? -57.150 38.121 -33.917 1.00 54.72 ? 138 ASP L O 1 ATOM 6784 C CB . ASP D 4 142 ? -56.971 38.836 -36.492 1.00 58.06 ? 138 ASP L CB 1 ATOM 6785 C CG . ASP D 4 142 ? -56.795 39.725 -37.690 1.00 67.58 ? 138 ASP L CG 1 ATOM 6786 O OD1 . ASP D 4 142 ? -56.029 40.709 -37.600 1.00 64.74 ? 138 ASP L OD1 1 ATOM 6787 O OD2 . ASP D 4 142 ? -57.423 39.434 -38.728 1.00 82.44 ? 138 ASP L OD2 1 ATOM 6788 N N . PHE D 4 143 ? -55.020 37.463 -33.665 1.00 44.26 ? 139 PHE L N 1 ATOM 6789 C CA . PHE D 4 143 ? -55.265 37.073 -32.273 1.00 44.24 ? 139 PHE L CA 1 ATOM 6790 C C . PHE D 4 143 ? -54.589 37.998 -31.265 1.00 54.83 ? 139 PHE L C 1 ATOM 6791 O O . PHE D 4 143 ? -53.597 38.666 -31.585 1.00 50.53 ? 139 PHE L O 1 ATOM 6792 C CB . PHE D 4 143 ? -54.904 35.618 -31.980 1.00 45.44 ? 139 PHE L CB 1 ATOM 6793 C CG . PHE D 4 143 ? -53.479 35.245 -32.336 1.00 52.88 ? 139 PHE L CG 1 ATOM 6794 C CD1 . PHE D 4 143 ? -53.131 34.903 -33.648 1.00 56.12 ? 139 PHE L CD1 1 ATOM 6795 C CD2 . PHE D 4 143 ? -52.492 35.201 -31.355 1.00 48.06 ? 139 PHE L CD2 1 ATOM 6796 C CE1 . PHE D 4 143 ? -51.818 34.546 -33.963 1.00 55.29 ? 139 PHE L CE1 1 ATOM 6797 C CE2 . PHE D 4 143 ? -51.183 34.844 -31.671 1.00 50.23 ? 139 PHE L CE2 1 ATOM 6798 C CZ . PHE D 4 143 ? -50.845 34.527 -32.964 1.00 49.67 ? 139 PHE L CZ 1 ATOM 6799 N N . TYR D 4 144 ? -55.152 38.028 -30.058 1.00 55.81 ? 140 TYR L N 1 ATOM 6800 C CA . TYR D 4 144 ? -54.619 38.790 -28.929 1.00 51.30 ? 140 TYR L CA 1 ATOM 6801 C C . TYR D 4 144 ? -55.185 38.198 -27.639 1.00 56.18 ? 140 TYR L C 1 ATOM 6802 O O . TYR D 4 144 ? -56.378 37.897 -27.580 1.00 53.16 ? 140 TYR L O 1 ATOM 6803 C CB . TYR D 4 144 ? -54.970 40.276 -29.006 1.00 39.12 ? 140 TYR L CB 1 ATOM 6804 C CG . TYR D 4 144 ? -54.343 41.050 -27.861 1.00 44.93 ? 140 TYR L CG 1 ATOM 6805 C CD1 . TYR D 4 144 ? -55.019 41.235 -26.647 1.00 43.08 ? 140 TYR L CD1 1 ATOM 6806 C CD2 . TYR D 4 144 ? -53.062 41.564 -27.971 1.00 51.13 ? 140 TYR L CD2 1 ATOM 6807 C CE1 . TYR D 4 144 ? -54.434 41.934 -25.588 1.00 46.32 ? 140 TYR L CE1 1 ATOM 6808 C CE2 . TYR D 4 144 ? -52.462 42.266 -26.905 1.00 53.32 ? 140 TYR L CE2 1 ATOM 6809 C CZ . TYR D 4 144 ? -53.143 42.434 -25.716 1.00 52.23 ? 140 TYR L CZ 1 ATOM 6810 O OH . TYR D 4 144 ? -52.536 43.136 -24.676 1.00 41.05 ? 140 TYR L OH 1 ATOM 6811 N N . PRO D 4 145 ? -54.338 38.019 -26.606 1.00 57.82 ? 141 PRO L N 1 ATOM 6812 C CA . PRO D 4 145 ? -52.884 38.265 -26.543 1.00 53.25 ? 141 PRO L CA 1 ATOM 6813 C C . PRO D 4 145 ? -52.081 37.408 -27.543 1.00 58.51 ? 141 PRO L C 1 ATOM 6814 O O . PRO D 4 145 ? -52.649 36.460 -28.110 1.00 46.81 ? 141 PRO L O 1 ATOM 6815 C CB . PRO D 4 145 ? -52.530 37.874 -25.105 1.00 51.00 ? 141 PRO L CB 1 ATOM 6816 C CG . PRO D 4 145 ? -53.806 38.067 -24.351 1.00 56.47 ? 141 PRO L CG 1 ATOM 6817 C CD . PRO D 4 145 ? -54.859 37.577 -25.304 1.00 55.54 ? 141 PRO L CD 1 ATOM 6818 N N . GLY D 4 146 ? -50.802 37.746 -27.754 1.00 47.41 ? 142 GLY L N 1 ATOM 6819 C CA . GLY D 4 146 ? -50.000 37.177 -28.836 1.00 42.61 ? 142 GLY L CA 1 ATOM 6820 C C . GLY D 4 146 ? -49.318 35.853 -28.558 1.00 47.07 ? 142 GLY L C 1 ATOM 6821 O O . GLY D 4 146 ? -48.105 35.711 -28.694 1.00 46.42 ? 142 GLY L O 1 ATOM 6822 N N . ALA D 4 147 ? -50.101 34.861 -28.176 1.00 49.78 ? 143 ALA L N 1 ATOM 6823 C CA . ALA D 4 147 ? -49.541 33.565 -27.868 1.00 54.89 ? 143 ALA L CA 1 ATOM 6824 C C . ALA D 4 147 ? -50.560 32.467 -28.176 1.00 71.27 ? 143 ALA L C 1 ATOM 6825 O O . ALA D 4 147 ? -51.597 32.366 -27.513 1.00 71.19 ? 143 ALA L O 1 ATOM 6826 C CB . ALA D 4 147 ? -49.128 33.521 -26.414 1.00 47.31 ? 143 ALA L CB 1 ATOM 6827 N N . VAL D 4 148 ? -50.262 31.659 -29.193 1.00 62.25 ? 144 VAL L N 1 ATOM 6828 C CA . VAL D 4 148 ? -51.083 30.506 -29.542 1.00 61.31 ? 144 VAL L CA 1 ATOM 6829 C C . VAL D 4 148 ? -50.263 29.233 -29.461 1.00 61.88 ? 144 VAL L C 1 ATOM 6830 O O . VAL D 4 148 ? -49.031 29.271 -29.455 1.00 64.15 ? 144 VAL L O 1 ATOM 6831 C CB . VAL D 4 148 ? -51.652 30.621 -30.979 1.00 60.13 ? 144 VAL L CB 1 ATOM 6832 C CG1 . VAL D 4 148 ? -52.644 31.751 -31.063 1.00 49.45 ? 144 VAL L CG1 1 ATOM 6833 C CG2 . VAL D 4 148 ? -50.515 30.828 -31.986 1.00 53.04 ? 144 VAL L CG2 1 ATOM 6834 N N . THR D 4 149 ? -50.944 28.098 -29.383 1.00 62.94 ? 145 THR L N 1 ATOM 6835 C CA . THR D 4 149 ? -50.261 26.826 -29.574 1.00 66.11 ? 145 THR L CA 1 ATOM 6836 C C . THR D 4 149 ? -50.956 26.077 -30.727 1.00 66.68 ? 145 THR L C 1 ATOM 6837 O O . THR D 4 149 ? -52.146 26.288 -30.993 1.00 61.30 ? 145 THR L O 1 ATOM 6838 C CB . THR D 4 149 ? -50.143 26.011 -28.252 1.00 71.64 ? 145 THR L CB 1 ATOM 6839 O OG1 . THR D 4 149 ? -48.878 25.339 -28.211 1.00 81.45 ? 145 THR L OG1 1 ATOM 6840 C CG2 . THR D 4 149 ? -51.255 24.995 -28.122 1.00 66.11 ? 145 THR L CG2 1 ATOM 6841 N N . VAL D 4 150 ? -50.197 25.248 -31.441 1.00 65.94 ? 146 VAL L N 1 ATOM 6842 C CA . VAL D 4 150 ? -50.689 24.621 -32.666 1.00 60.41 ? 146 VAL L CA 1 ATOM 6843 C C . VAL D 4 150 ? -50.571 23.098 -32.612 1.00 70.72 ? 146 VAL L C 1 ATOM 6844 O O . VAL D 4 150 ? -49.493 22.553 -32.355 1.00 70.42 ? 146 VAL L O 1 ATOM 6845 C CB . VAL D 4 150 ? -49.934 25.150 -33.906 1.00 59.31 ? 146 VAL L CB 1 ATOM 6846 C CG1 . VAL D 4 150 ? -50.394 24.424 -35.163 1.00 58.83 ? 146 VAL L CG1 1 ATOM 6847 C CG2 . VAL D 4 150 ? -50.132 26.669 -34.058 1.00 51.05 ? 146 VAL L CG2 1 ATOM 6848 N N . ALA D 4 151 ? -51.690 22.418 -32.838 1.00 75.89 ? 147 ALA L N 1 ATOM 6849 C CA . ALA D 4 151 ? -51.698 20.962 -32.918 1.00 78.32 ? 147 ALA L CA 1 ATOM 6850 C C . ALA D 4 151 ? -52.154 20.521 -34.310 1.00 70.86 ? 147 ALA L C 1 ATOM 6851 O O . ALA D 4 151 ? -53.115 21.056 -34.861 1.00 74.71 ? 147 ALA L O 1 ATOM 6852 C CB . ALA D 4 151 ? -52.602 20.378 -31.843 1.00 62.30 ? 147 ALA L CB 1 ATOM 6853 N N . TRP D 4 152 ? -51.447 19.559 -34.892 1.00 76.95 ? 148 TRP L N 1 ATOM 6854 C CA . TRP D 4 152 ? -51.846 19.035 -36.194 1.00 81.52 ? 148 TRP L CA 1 ATOM 6855 C C . TRP D 4 152 ? -52.504 17.659 -36.040 1.00 86.70 ? 148 TRP L C 1 ATOM 6856 O O . TRP D 4 152 ? -52.045 16.824 -35.249 1.00 79.43 ? 148 TRP L O 1 ATOM 6857 C CB . TRP D 4 152 ? -50.655 18.959 -37.147 1.00 72.55 ? 148 TRP L CB 1 ATOM 6858 C CG . TRP D 4 152 ? -50.199 20.221 -37.722 1.00 71.78 ? 148 TRP L CG 1 ATOM 6859 C CD1 . TRP D 4 152 ? -49.266 21.063 -37.205 1.00 68.71 ? 148 TRP L CD1 1 ATOM 6860 C CD2 . TRP D 4 152 ? -50.632 20.803 -38.960 1.00 72.42 ? 148 TRP L CD2 1 ATOM 6861 N NE1 . TRP D 4 152 ? -49.100 22.146 -38.037 1.00 68.18 ? 148 TRP L NE1 1 ATOM 6862 C CE2 . TRP D 4 152 ? -49.927 22.011 -39.122 1.00 67.71 ? 148 TRP L CE2 1 ATOM 6863 C CE3 . TRP D 4 152 ? -51.555 20.423 -39.943 1.00 78.15 ? 148 TRP L CE3 1 ATOM 6864 C CZ2 . TRP D 4 152 ? -50.112 22.845 -40.232 1.00 62.02 ? 148 TRP L CZ2 1 ATOM 6865 C CZ3 . TRP D 4 152 ? -51.737 21.251 -41.044 1.00 71.16 ? 148 TRP L CZ3 1 ATOM 6866 C CH2 . TRP D 4 152 ? -51.017 22.446 -41.180 1.00 70.18 ? 148 TRP L CH2 1 ATOM 6867 N N . LYS D 4 153 ? -53.581 17.438 -36.799 1.00 86.92 ? 149 LYS L N 1 ATOM 6868 C CA . LYS D 4 153 ? -54.337 16.182 -36.747 1.00 88.87 ? 149 LYS L CA 1 ATOM 6869 C C . LYS D 4 153 ? -54.301 15.375 -38.046 1.00 89.27 ? 149 LYS L C 1 ATOM 6870 O O . LYS D 4 153 ? -54.797 15.825 -39.083 1.00 87.51 ? 149 LYS L O 1 ATOM 6871 C CB . LYS D 4 153 ? -55.793 16.454 -36.368 1.00 86.24 ? 149 LYS L CB 1 ATOM 6872 C CG . LYS D 4 153 ? -55.987 16.795 -34.906 1.00 100.14 ? 149 LYS L CG 1 ATOM 6873 C CD . LYS D 4 153 ? -55.485 15.674 -34.004 1.00 107.42 ? 149 LYS L CD 1 ATOM 6874 C CE . LYS D 4 153 ? -55.552 16.065 -32.531 1.00 104.51 ? 149 LYS L CE 1 ATOM 6875 N NZ . LYS D 4 153 ? -56.926 16.465 -32.102 1.00 100.92 ? 149 LYS L NZ 1 ATOM 6876 N N . ALA D 4 154 ? -53.725 14.177 -37.976 1.00 87.23 ? 150 ALA L N 1 ATOM 6877 C CA . ALA D 4 154 ? -53.757 13.232 -39.092 1.00 94.04 ? 150 ALA L CA 1 ATOM 6878 C C . ALA D 4 154 ? -54.936 12.282 -38.891 1.00 97.17 ? 150 ALA L C 1 ATOM 6879 O O . ALA D 4 154 ? -54.894 11.423 -38.003 1.00 101.41 ? 150 ALA L O 1 ATOM 6880 C CB . ALA D 4 154 ? -52.455 12.452 -39.155 1.00 90.65 ? 150 ALA L CB 1 ATOM 6881 N N . ASP D 4 155 ? -55.969 12.425 -39.723 1.00 95.74 ? 151 ASP L N 1 ATOM 6882 C CA . ASP D 4 155 ? -57.296 11.879 -39.414 1.00 102.34 ? 151 ASP L CA 1 ATOM 6883 C C . ASP D 4 155 ? -57.715 12.458 -38.062 1.00 100.23 ? 151 ASP L C 1 ATOM 6884 O O . ASP D 4 155 ? -58.121 13.620 -37.979 1.00 103.97 ? 151 ASP L O 1 ATOM 6885 C CB . ASP D 4 155 ? -57.322 10.336 -39.398 1.00 100.42 ? 151 ASP L CB 1 ATOM 6886 C CG . ASP D 4 155 ? -57.188 9.720 -40.796 1.00 100.39 ? 151 ASP L CG 1 ATOM 6887 O OD1 . ASP D 4 155 ? -57.887 10.170 -41.737 1.00 94.85 ? 151 ASP L OD1 1 ATOM 6888 O OD2 . ASP D 4 155 ? -56.378 8.777 -40.946 1.00 90.29 ? 151 ASP L OD2 1 ATOM 6889 N N . SER D 4 156 ? -57.587 11.666 -37.000 1.00 99.50 ? 152 SER L N 1 ATOM 6890 C CA . SER D 4 156 ? -57.838 12.174 -35.653 1.00 93.98 ? 152 SER L CA 1 ATOM 6891 C C . SER D 4 156 ? -56.657 11.954 -34.710 1.00 94.65 ? 152 SER L C 1 ATOM 6892 O O . SER D 4 156 ? -56.726 12.298 -33.530 1.00 95.18 ? 152 SER L O 1 ATOM 6893 C CB . SER D 4 156 ? -59.123 11.578 -35.067 1.00 94.46 ? 152 SER L CB 1 ATOM 6894 O OG . SER D 4 156 ? -60.240 12.410 -35.352 1.00 91.50 ? 152 SER L OG 1 ATOM 6895 N N . SER D 4 157 ? -55.573 11.392 -35.237 1.00 92.22 ? 153 SER L N 1 ATOM 6896 C CA . SER D 4 157 ? -54.357 11.209 -34.451 1.00 93.51 ? 153 SER L CA 1 ATOM 6897 C C . SER D 4 157 ? -53.406 12.416 -34.520 1.00 95.11 ? 153 SER L C 1 ATOM 6898 O O . SER D 4 157 ? -53.339 13.116 -35.537 1.00 90.86 ? 153 SER L O 1 ATOM 6899 C CB . SER D 4 157 ? -53.642 9.923 -34.866 1.00 86.24 ? 153 SER L CB 1 ATOM 6900 O OG . SER D 4 157 ? -54.392 8.791 -34.465 1.00 96.98 ? 153 SER L OG 1 ATOM 6901 N N . PRO D 4 158 ? -52.686 12.677 -33.416 1.00 92.94 ? 154 PRO L N 1 ATOM 6902 C CA . PRO D 4 158 ? -51.682 13.744 -33.369 1.00 100.36 ? 154 PRO L CA 1 ATOM 6903 C C . PRO D 4 158 ? -50.425 13.340 -34.128 1.00 100.96 ? 154 PRO L C 1 ATOM 6904 O O . PRO D 4 158 ? -49.841 12.283 -33.860 1.00 91.71 ? 154 PRO L O 1 ATOM 6905 C CB . PRO D 4 158 ? -51.359 13.865 -31.871 1.00 94.21 ? 154 PRO L CB 1 ATOM 6906 C CG . PRO D 4 158 ? -52.467 13.152 -31.164 1.00 97.24 ? 154 PRO L CG 1 ATOM 6907 C CD . PRO D 4 158 ? -52.882 12.060 -32.096 1.00 95.98 ? 154 PRO L CD 1 ATOM 6908 N N . VAL D 4 159 ? -50.022 14.181 -35.073 1.00 98.28 ? 155 VAL L N 1 ATOM 6909 C CA . VAL D 4 159 ? -48.764 13.999 -35.782 1.00 94.83 ? 155 VAL L CA 1 ATOM 6910 C C . VAL D 4 159 ? -47.612 14.378 -34.847 1.00 100.53 ? 155 VAL L C 1 ATOM 6911 O O . VAL D 4 159 ? -47.713 15.337 -34.075 1.00 106.40 ? 155 VAL L O 1 ATOM 6912 C CB . VAL D 4 159 ? -48.723 14.902 -37.008 1.00 87.52 ? 155 VAL L CB 1 ATOM 6913 C CG1 . VAL D 4 159 ? -49.172 16.252 -36.603 1.00 84.86 ? 155 VAL L CG1 1 ATOM 6914 C CG2 . VAL D 4 159 ? -47.318 14.984 -37.574 1.00 76.92 ? 155 VAL L CG2 1 ATOM 6915 N N . LYS D 4 160 ? -46.525 13.618 -34.894 1.00 94.11 ? 156 LYS L N 1 ATOM 6916 C CA . LYS D 4 160 ? -45.359 13.953 -34.091 1.00 96.57 ? 156 LYS L CA 1 ATOM 6917 C C . LYS D 4 160 ? -44.113 14.136 -34.963 1.00 97.63 ? 156 LYS L C 1 ATOM 6918 O O . LYS D 4 160 ? -43.023 13.695 -34.582 1.00 98.60 ? 156 LYS L O 1 ATOM 6919 C CB . LYS D 4 160 ? -45.118 12.870 -33.037 1.00 94.80 ? 156 LYS L CB 1 ATOM 6920 C CG . LYS D 4 160 ? -44.560 13.382 -31.712 1.00 94.00 ? 156 LYS L CG 1 ATOM 6921 C CD . LYS D 4 160 ? -44.591 12.278 -30.659 1.00 90.23 ? 156 LYS L CD 1 ATOM 6922 C CE . LYS D 4 160 ? -45.979 11.638 -30.562 1.00 90.97 ? 156 LYS L CE 1 ATOM 6923 N NZ . LYS D 4 160 ? -45.978 10.330 -29.839 1.00 90.31 ? 156 LYS L NZ 1 ATOM 6924 N N . ALA D 4 161 ? -44.275 14.781 -36.123 1.00 85.13 ? 157 ALA L N 1 ATOM 6925 C CA . ALA D 4 161 ? -43.161 15.003 -37.055 1.00 79.55 ? 157 ALA L CA 1 ATOM 6926 C C . ALA D 4 161 ? -43.482 16.007 -38.155 1.00 81.70 ? 157 ALA L C 1 ATOM 6927 O O . ALA D 4 161 ? -44.625 16.116 -38.602 1.00 81.18 ? 157 ALA L O 1 ATOM 6928 C CB . ALA D 4 161 ? -42.717 13.688 -37.689 1.00 83.25 ? 157 ALA L CB 1 ATOM 6929 N N . GLY D 4 162 ? -42.455 16.722 -38.605 1.00 86.72 ? 158 GLY L N 1 ATOM 6930 C CA . GLY D 4 162 ? -42.578 17.608 -39.753 1.00 80.71 ? 158 GLY L CA 1 ATOM 6931 C C . GLY D 4 162 ? -43.423 18.850 -39.517 1.00 62.58 ? 158 GLY L C 1 ATOM 6932 O O . GLY D 4 162 ? -43.845 19.526 -40.466 1.00 62.80 ? 158 GLY L O 1 ATOM 6933 N N . VAL D 4 163 ? -43.681 19.139 -38.250 1.00 67.07 ? 159 VAL L N 1 ATOM 6934 C CA . VAL D 4 163 ? -44.384 20.358 -37.870 1.00 69.58 ? 159 VAL L CA 1 ATOM 6935 C C . VAL D 4 163 ? -43.382 21.463 -37.530 1.00 66.52 ? 159 VAL L C 1 ATOM 6936 O O . VAL D 4 163 ? -42.547 21.319 -36.622 1.00 59.81 ? 159 VAL L O 1 ATOM 6937 C CB . VAL D 4 163 ? -45.296 20.132 -36.651 1.00 61.20 ? 159 VAL L CB 1 ATOM 6938 C CG1 . VAL D 4 163 ? -45.952 21.461 -36.205 1.00 58.89 ? 159 VAL L CG1 1 ATOM 6939 C CG2 . VAL D 4 163 ? -46.339 19.069 -36.957 1.00 72.59 ? 159 VAL L CG2 1 ATOM 6940 N N . GLU D 4 164 ? -43.465 22.561 -38.265 1.00 58.32 ? 160 GLU L N 1 ATOM 6941 C CA . GLU D 4 164 ? -42.640 23.723 -37.976 1.00 58.36 ? 160 GLU L CA 1 ATOM 6942 C C . GLU D 4 164 ? -43.532 24.948 -37.900 1.00 54.98 ? 160 GLU L C 1 ATOM 6943 O O . GLU D 4 164 ? -44.237 25.273 -38.863 1.00 50.84 ? 160 GLU L O 1 ATOM 6944 C CB . GLU D 4 164 ? -41.542 23.875 -39.036 1.00 58.89 ? 160 GLU L CB 1 ATOM 6945 C CG . GLU D 4 164 ? -40.328 22.966 -38.749 1.00 65.68 ? 160 GLU L CG 1 ATOM 6946 C CD . GLU D 4 164 ? -39.309 22.907 -39.884 1.00 61.81 ? 160 GLU L CD 1 ATOM 6947 O OE1 . GLU D 4 164 ? -39.702 23.159 -41.047 1.00 59.54 ? 160 GLU L OE1 1 ATOM 6948 O OE2 . GLU D 4 164 ? -38.118 22.589 -39.601 1.00 60.09 ? 160 GLU L OE2 1 ATOM 6949 N N . THR D 4 165 ? -43.493 25.619 -36.749 1.00 55.33 ? 161 THR L N 1 ATOM 6950 C CA . THR D 4 165 ? -44.344 26.775 -36.473 1.00 48.81 ? 161 THR L CA 1 ATOM 6951 C C . THR D 4 165 ? -43.526 28.009 -36.054 1.00 49.66 ? 161 THR L C 1 ATOM 6952 O O . THR D 4 165 ? -42.621 27.903 -35.211 1.00 44.99 ? 161 THR L O 1 ATOM 6953 C CB . THR D 4 165 ? -45.281 26.465 -35.291 1.00 52.24 ? 161 THR L CB 1 ATOM 6954 O OG1 . THR D 4 165 ? -45.925 25.202 -35.506 1.00 48.53 ? 161 THR L OG1 1 ATOM 6955 C CG2 . THR D 4 165 ? -46.312 27.560 -35.151 1.00 50.78 ? 161 THR L CG2 1 ATOM 6956 N N . THR D 4 166 ? -43.875 29.169 -36.611 1.00 41.97 ? 162 THR L N 1 ATOM 6957 C CA . THR D 4 166 ? -43.143 30.410 -36.345 1.00 41.32 ? 162 THR L CA 1 ATOM 6958 C C . THR D 4 166 ? -43.485 30.929 -34.963 1.00 49.94 ? 162 THR L C 1 ATOM 6959 O O . THR D 4 166 ? -44.466 30.500 -34.350 1.00 52.74 ? 162 THR L O 1 ATOM 6960 C CB . THR D 4 166 ? -43.554 31.525 -37.285 1.00 36.82 ? 162 THR L CB 1 ATOM 6961 O OG1 . THR D 4 166 ? -44.924 31.907 -37.030 1.00 41.82 ? 162 THR L OG1 1 ATOM 6962 C CG2 . THR D 4 166 ? -43.415 31.131 -38.763 1.00 38.45 ? 162 THR L CG2 1 ATOM 6963 N N . THR D 4 167 ? -42.685 31.880 -34.482 1.00 41.86 ? 163 THR L N 1 ATOM 6964 C CA . THR D 4 167 ? -43.056 32.661 -33.309 1.00 42.69 ? 163 THR L CA 1 ATOM 6965 C C . THR D 4 167 ? -44.203 33.586 -33.700 1.00 36.73 ? 163 THR L C 1 ATOM 6966 O O . THR D 4 167 ? -44.383 33.914 -34.874 1.00 42.94 ? 163 THR L O 1 ATOM 6967 C CB . THR D 4 167 ? -41.866 33.550 -32.834 1.00 48.73 ? 163 THR L CB 1 ATOM 6968 O OG1 . THR D 4 167 ? -41.450 34.422 -33.902 1.00 43.45 ? 163 THR L OG1 1 ATOM 6969 C CG2 . THR D 4 167 ? -40.707 32.692 -32.388 1.00 47.30 ? 163 THR L CG2 1 ATOM 6970 N N . PRO D 4 168 ? -44.975 34.050 -32.709 1.00 45.12 ? 164 PRO L N 1 ATOM 6971 C CA . PRO D 4 168 ? -45.999 35.058 -32.978 1.00 44.40 ? 164 PRO L CA 1 ATOM 6972 C C . PRO D 4 168 ? -45.376 36.409 -33.291 1.00 43.71 ? 164 PRO L C 1 ATOM 6973 O O . PRO D 4 168 ? -44.372 36.794 -32.656 1.00 46.49 ? 164 PRO L O 1 ATOM 6974 C CB . PRO D 4 168 ? -46.760 35.136 -31.647 1.00 49.47 ? 164 PRO L CB 1 ATOM 6975 C CG . PRO D 4 168 ? -45.759 34.755 -30.648 1.00 51.85 ? 164 PRO L CG 1 ATOM 6976 C CD . PRO D 4 168 ? -44.943 33.667 -31.293 1.00 46.34 ? 164 PRO L CD 1 ATOM 6977 N N . SER D 4 169 ? -45.965 37.125 -34.243 1.00 35.55 ? 165 SER L N 1 ATOM 6978 C CA . SER D 4 169 ? -45.505 38.455 -34.630 1.00 49.56 ? 165 SER L CA 1 ATOM 6979 C C . SER D 4 169 ? -46.637 39.472 -34.637 1.00 52.41 ? 165 SER L C 1 ATOM 6980 O O . SER D 4 169 ? -47.769 39.172 -35.022 1.00 49.28 ? 165 SER L O 1 ATOM 6981 C CB . SER D 4 169 ? -44.849 38.433 -36.016 1.00 48.90 ? 165 SER L CB 1 ATOM 6982 O OG . SER D 4 169 ? -45.828 38.533 -37.044 1.00 64.03 ? 165 SER L OG 1 ATOM 6983 N N . LYS D 4 170 ? -46.327 40.693 -34.230 1.00 45.17 ? 166 LYS L N 1 ATOM 6984 C CA . LYS D 4 170 ? -47.352 41.726 -34.121 1.00 44.08 ? 166 LYS L CA 1 ATOM 6985 C C . LYS D 4 170 ? -47.714 42.315 -35.484 1.00 54.65 ? 166 LYS L C 1 ATOM 6986 O O . LYS D 4 170 ? -46.834 42.750 -36.230 1.00 54.25 ? 166 LYS L O 1 ATOM 6987 C CB . LYS D 4 170 ? -46.864 42.831 -33.177 1.00 54.85 ? 166 LYS L CB 1 ATOM 6988 C CG . LYS D 4 170 ? -47.972 43.559 -32.407 1.00 57.39 ? 166 LYS L CG 1 ATOM 6989 C CD . LYS D 4 170 ? -47.458 44.845 -31.722 1.00 63.25 ? 166 LYS L CD 1 ATOM 6990 C CE . LYS D 4 170 ? -46.370 44.562 -30.670 1.00 73.68 ? 166 LYS L CE 1 ATOM 6991 N NZ . LYS D 4 170 ? -45.927 45.794 -29.921 1.00 74.21 ? 166 LYS L NZ 1 ATOM 6992 N N . GLN D 4 171 ? -49.014 42.340 -35.797 1.00 52.27 ? 167 GLN L N 1 ATOM 6993 C CA . GLN D 4 171 ? -49.508 42.924 -37.043 1.00 51.42 ? 167 GLN L CA 1 ATOM 6994 C C . GLN D 4 171 ? -49.658 44.415 -36.876 1.00 59.50 ? 167 GLN L C 1 ATOM 6995 O O . GLN D 4 171 ? -49.515 44.949 -35.767 1.00 54.46 ? 167 GLN L O 1 ATOM 6996 C CB . GLN D 4 171 ? -50.866 42.320 -37.458 1.00 50.88 ? 167 GLN L CB 1 ATOM 6997 C CG . GLN D 4 171 ? -50.994 40.851 -37.145 1.00 51.19 ? 167 GLN L CG 1 ATOM 6998 C CD . GLN D 4 171 ? -52.334 40.265 -37.580 1.00 60.55 ? 167 GLN L CD 1 ATOM 6999 O OE1 . GLN D 4 171 ? -52.405 39.120 -38.016 1.00 52.40 ? 167 GLN L OE1 1 ATOM 7000 N NE2 . GLN D 4 171 ? -53.403 41.045 -37.447 1.00 50.55 ? 167 GLN L NE2 1 ATOM 7001 N N . SER D 4 172 ? -49.958 45.090 -37.977 1.00 58.22 ? 168 SER L N 1 ATOM 7002 C CA . SER D 4 172 ? -50.176 46.530 -37.929 1.00 67.30 ? 168 SER L CA 1 ATOM 7003 C C . SER D 4 172 ? -51.345 46.889 -37.007 1.00 58.85 ? 168 SER L C 1 ATOM 7004 O O . SER D 4 172 ? -51.370 47.969 -36.419 1.00 68.06 ? 168 SER L O 1 ATOM 7005 C CB . SER D 4 172 ? -50.442 47.067 -39.330 1.00 62.94 ? 168 SER L CB 1 ATOM 7006 O OG . SER D 4 172 ? -51.437 46.279 -39.952 1.00 74.05 ? 168 SER L OG 1 ATOM 7007 N N . ASN D 4 173 ? -52.305 45.981 -36.874 1.00 57.22 ? 169 ASN L N 1 ATOM 7008 C CA . ASN D 4 173 ? -53.481 46.273 -36.062 1.00 63.92 ? 169 ASN L CA 1 ATOM 7009 C C . ASN D 4 173 ? -53.291 45.891 -34.592 1.00 67.31 ? 169 ASN L C 1 ATOM 7010 O O . ASN D 4 173 ? -54.266 45.690 -33.862 1.00 61.77 ? 169 ASN L O 1 ATOM 7011 C CB . ASN D 4 173 ? -54.724 45.608 -36.653 1.00 59.85 ? 169 ASN L CB 1 ATOM 7012 C CG . ASN D 4 173 ? -54.682 44.090 -36.565 1.00 66.15 ? 169 ASN L CG 1 ATOM 7013 O OD1 . ASN D 4 173 ? -53.795 43.512 -35.934 1.00 65.08 ? 169 ASN L OD1 1 ATOM 7014 N ND2 . ASN D 4 173 ? -55.659 43.434 -37.189 1.00 67.72 ? 169 ASN L ND2 1 ATOM 7015 N N . ASN D 4 174 ? -52.030 45.755 -34.187 1.00 58.77 ? 170 ASN L N 1 ATOM 7016 C CA . ASN D 4 174 ? -51.666 45.440 -32.811 1.00 60.25 ? 170 ASN L CA 1 ATOM 7017 C C . ASN D 4 174 ? -52.148 44.080 -32.310 1.00 54.97 ? 170 ASN L C 1 ATOM 7018 O O . ASN D 4 174 ? -52.014 43.765 -31.128 1.00 54.02 ? 170 ASN L O 1 ATOM 7019 C CB . ASN D 4 174 ? -52.091 46.571 -31.863 1.00 66.76 ? 170 ASN L CB 1 ATOM 7020 C CG . ASN D 4 174 ? -51.185 47.786 -31.971 1.00 69.69 ? 170 ASN L CG 1 ATOM 7021 O OD1 . ASN D 4 174 ? -49.969 47.654 -32.107 1.00 66.32 ? 170 ASN L OD1 1 ATOM 7022 N ND2 . ASN D 4 174 ? -51.774 48.974 -31.921 1.00 70.95 ? 170 ASN L ND2 1 ATOM 7023 N N . LYS D 4 175 ? -52.721 43.281 -33.208 1.00 48.00 ? 171 LYS L N 1 ATOM 7024 C CA . LYS D 4 175 ? -52.984 41.883 -32.912 1.00 47.21 ? 171 LYS L CA 1 ATOM 7025 C C . LYS D 4 175 ? -51.822 41.084 -33.494 1.00 41.92 ? 171 LYS L C 1 ATOM 7026 O O . LYS D 4 175 ? -50.937 41.667 -34.121 1.00 46.91 ? 171 LYS L O 1 ATOM 7027 C CB . LYS D 4 175 ? -54.308 41.443 -33.549 1.00 56.78 ? 171 LYS L CB 1 ATOM 7028 C CG . LYS D 4 175 ? -55.516 42.211 -33.038 1.00 59.22 ? 171 LYS L CG 1 ATOM 7029 C CD . LYS D 4 175 ? -56.815 41.656 -33.605 1.00 66.05 ? 171 LYS L CD 1 ATOM 7030 C CE . LYS D 4 175 ? -58.019 42.439 -33.087 1.00 78.59 ? 171 LYS L CE 1 ATOM 7031 N NZ . LYS D 4 175 ? -59.285 41.978 -33.720 1.00 86.39 ? 171 LYS L NZ 1 ATOM 7032 N N . TYR D 4 176 ? -51.828 39.769 -33.297 1.00 41.02 ? 172 TYR L N 1 ATOM 7033 C CA . TYR D 4 176 ? -50.700 38.935 -33.719 1.00 40.77 ? 172 TYR L CA 1 ATOM 7034 C C . TYR D 4 176 ? -50.990 37.948 -34.853 1.00 50.61 ? 172 TYR L C 1 ATOM 7035 O O . TYR D 4 176 ? -52.140 37.584 -35.129 1.00 48.04 ? 172 TYR L O 1 ATOM 7036 C CB . TYR D 4 176 ? -50.136 38.175 -32.523 1.00 38.82 ? 172 TYR L CB 1 ATOM 7037 C CG . TYR D 4 176 ? -49.466 39.105 -31.521 1.00 49.90 ? 172 TYR L CG 1 ATOM 7038 C CD1 . TYR D 4 176 ? -48.072 39.118 -31.362 1.00 51.70 ? 172 TYR L CD1 1 ATOM 7039 C CD2 . TYR D 4 176 ? -50.226 40.003 -30.754 1.00 50.60 ? 172 TYR L CD2 1 ATOM 7040 C CE1 . TYR D 4 176 ? -47.461 39.988 -30.450 1.00 53.14 ? 172 TYR L CE1 1 ATOM 7041 C CE2 . TYR D 4 176 ? -49.626 40.868 -29.833 1.00 54.96 ? 172 TYR L CE2 1 ATOM 7042 C CZ . TYR D 4 176 ? -48.245 40.861 -29.686 1.00 60.94 ? 172 TYR L CZ 1 ATOM 7043 O OH . TYR D 4 176 ? -47.654 41.726 -28.779 1.00 54.14 ? 172 TYR L OH 1 ATOM 7044 N N . ALA D 4 177 ? -49.914 37.498 -35.493 1.00 44.71 ? 173 ALA L N 1 ATOM 7045 C CA . ALA D 4 177 ? -50.019 36.501 -36.549 1.00 45.53 ? 173 ALA L CA 1 ATOM 7046 C C . ALA D 4 177 ? -48.961 35.433 -36.322 1.00 50.56 ? 173 ALA L C 1 ATOM 7047 O O . ALA D 4 177 ? -47.902 35.696 -35.726 1.00 44.04 ? 173 ALA L O 1 ATOM 7048 C CB . ALA D 4 177 ? -49.851 37.167 -37.906 1.00 40.48 ? 173 ALA L CB 1 ATOM 7049 N N . ALA D 4 178 ? -49.260 34.216 -36.745 1.00 46.17 ? 174 ALA L N 1 ATOM 7050 C CA . ALA D 4 178 ? -48.267 33.153 -36.767 1.00 38.75 ? 174 ALA L CA 1 ATOM 7051 C C . ALA D 4 178 ? -48.511 32.308 -38.018 1.00 44.13 ? 174 ALA L C 1 ATOM 7052 O O . ALA D 4 178 ? -49.427 32.595 -38.803 1.00 43.92 ? 174 ALA L O 1 ATOM 7053 C CB . ALA D 4 178 ? -48.369 32.308 -35.527 1.00 47.39 ? 174 ALA L CB 1 ATOM 7054 N N . SER D 4 179 ? -47.686 31.291 -38.218 1.00 44.43 ? 175 SER L N 1 ATOM 7055 C CA . SER D 4 179 ? -47.966 30.325 -39.278 1.00 43.79 ? 175 SER L CA 1 ATOM 7056 C C . SER D 4 179 ? -47.310 28.993 -38.942 1.00 46.27 ? 175 SER L C 1 ATOM 7057 O O . SER D 4 179 ? -46.279 28.951 -38.287 1.00 46.49 ? 175 SER L O 1 ATOM 7058 C CB . SER D 4 179 ? -47.628 30.878 -40.693 1.00 50.28 ? 175 SER L CB 1 ATOM 7059 O OG . SER D 4 179 ? -46.303 31.370 -40.848 1.00 45.36 ? 175 SER L OG 1 ATOM 7060 N N . SER D 4 180 ? -47.939 27.894 -39.336 1.00 45.79 ? 176 SER L N 1 ATOM 7061 C CA . SER D 4 180 ? -47.375 26.598 -39.037 1.00 50.24 ? 176 SER L CA 1 ATOM 7062 C C . SER D 4 180 ? -47.402 25.752 -40.289 1.00 47.16 ? 176 SER L C 1 ATOM 7063 O O . SER D 4 180 ? -48.345 25.829 -41.072 1.00 52.16 ? 176 SER L O 1 ATOM 7064 C CB . SER D 4 180 ? -48.135 25.895 -37.924 1.00 53.24 ? 176 SER L CB 1 ATOM 7065 O OG . SER D 4 180 ? -47.507 24.660 -37.630 1.00 58.26 ? 176 SER L OG 1 ATOM 7066 N N . TYR D 4 181 ? -46.352 24.961 -40.469 1.00 49.40 ? 177 TYR L N 1 ATOM 7067 C CA . TYR D 4 181 ? -46.166 24.216 -41.694 1.00 47.32 ? 177 TYR L CA 1 ATOM 7068 C C . TYR D 4 181 ? -46.083 22.721 -41.392 1.00 55.63 ? 177 TYR L C 1 ATOM 7069 O O . TYR D 4 181 ? -45.372 22.286 -40.466 1.00 53.17 ? 177 TYR L O 1 ATOM 7070 C CB . TYR D 4 181 ? -44.923 24.723 -42.445 1.00 40.54 ? 177 TYR L CB 1 ATOM 7071 C CG . TYR D 4 181 ? -45.084 26.132 -43.040 1.00 42.42 ? 177 TYR L CG 1 ATOM 7072 C CD1 . TYR D 4 181 ? -44.790 27.274 -42.298 1.00 41.68 ? 177 TYR L CD1 1 ATOM 7073 C CD2 . TYR D 4 181 ? -45.494 26.319 -44.358 1.00 39.08 ? 177 TYR L CD2 1 ATOM 7074 C CE1 . TYR D 4 181 ? -44.919 28.553 -42.862 1.00 35.70 ? 177 TYR L CE1 1 ATOM 7075 C CE2 . TYR D 4 181 ? -45.624 27.599 -44.923 1.00 46.89 ? 177 TYR L CE2 1 ATOM 7076 C CZ . TYR D 4 181 ? -45.321 28.721 -44.164 1.00 40.01 ? 177 TYR L CZ 1 ATOM 7077 O OH . TYR D 4 181 ? -45.444 29.997 -44.716 1.00 43.97 ? 177 TYR L OH 1 ATOM 7078 N N . LEU D 4 182 ? -46.868 21.947 -42.147 1.00 58.96 ? 178 LEU L N 1 ATOM 7079 C CA . LEU D 4 182 ? -46.818 20.488 -42.063 1.00 69.91 ? 178 LEU L CA 1 ATOM 7080 C C . LEU D 4 182 ? -46.217 19.901 -43.339 1.00 59.89 ? 178 LEU L C 1 ATOM 7081 O O . LEU D 4 182 ? -46.696 20.156 -44.454 1.00 50.44 ? 178 LEU L O 1 ATOM 7082 C CB . LEU D 4 182 ? -48.202 19.893 -41.807 1.00 68.94 ? 178 LEU L CB 1 ATOM 7083 C CG . LEU D 4 182 ? -48.121 18.397 -41.517 1.00 73.31 ? 178 LEU L CG 1 ATOM 7084 C CD1 . LEU D 4 182 ? -47.159 18.134 -40.361 1.00 69.88 ? 178 LEU L CD1 1 ATOM 7085 C CD2 . LEU D 4 182 ? -49.498 17.836 -41.229 1.00 70.45 ? 178 LEU L CD2 1 ATOM 7086 N N . SER D 4 183 ? -45.150 19.131 -43.165 1.00 59.25 ? 179 SER L N 1 ATOM 7087 C CA . SER D 4 183 ? -44.442 18.568 -44.302 1.00 69.95 ? 179 SER L CA 1 ATOM 7088 C C . SER D 4 183 ? -44.651 17.066 -44.356 1.00 72.65 ? 179 SER L C 1 ATOM 7089 O O . SER D 4 183 ? -44.327 16.345 -43.401 1.00 72.38 ? 179 SER L O 1 ATOM 7090 C CB . SER D 4 183 ? -42.948 18.882 -44.221 1.00 69.81 ? 179 SER L CB 1 ATOM 7091 O OG . SER D 4 183 ? -42.708 20.264 -44.439 1.00 60.56 ? 179 SER L OG 1 ATOM 7092 N N . LEU D 4 184 ? -45.185 16.611 -45.485 1.00 66.02 ? 180 LEU L N 1 ATOM 7093 C CA . LEU D 4 184 ? -45.544 15.212 -45.673 1.00 75.25 ? 180 LEU L CA 1 ATOM 7094 C C . LEU D 4 184 ? -45.130 14.725 -47.046 1.00 81.37 ? 180 LEU L C 1 ATOM 7095 O O . LEU D 4 184 ? -45.071 15.522 -47.998 1.00 68.69 ? 180 LEU L O 1 ATOM 7096 C CB . LEU D 4 184 ? -47.052 15.042 -45.530 1.00 68.10 ? 180 LEU L CB 1 ATOM 7097 C CG . LEU D 4 184 ? -47.545 15.295 -44.110 1.00 75.35 ? 180 LEU L CG 1 ATOM 7098 C CD1 . LEU D 4 184 ? -49.054 15.225 -44.068 1.00 75.23 ? 180 LEU L CD1 1 ATOM 7099 C CD2 . LEU D 4 184 ? -46.900 14.306 -43.120 1.00 75.37 ? 180 LEU L CD2 1 ATOM 7100 N N . THR D 4 185 ? -44.840 13.420 -47.132 1.00 78.16 ? 181 THR L N 1 ATOM 7101 C CA . THR D 4 185 ? -44.674 12.738 -48.414 1.00 86.82 ? 181 THR L CA 1 ATOM 7102 C C . THR D 4 185 ? -46.038 12.683 -49.081 1.00 81.62 ? 181 THR L C 1 ATOM 7103 O O . THR D 4 185 ? -47.046 12.517 -48.389 1.00 80.82 ? 181 THR L O 1 ATOM 7104 C CB . THR D 4 185 ? -44.176 11.294 -48.238 1.00 83.48 ? 181 THR L CB 1 ATOM 7105 O OG1 . THR D 4 185 ? -45.134 10.546 -47.482 1.00 77.10 ? 181 THR L OG1 1 ATOM 7106 C CG2 . THR D 4 185 ? -42.838 11.272 -47.521 1.00 84.38 ? 181 THR L CG2 1 ATOM 7107 N N . PRO D 4 186 ? -46.079 12.842 -50.422 1.00 86.17 ? 182 PRO L N 1 ATOM 7108 C CA . PRO D 4 186 ? -47.339 12.739 -51.170 1.00 83.27 ? 182 PRO L CA 1 ATOM 7109 C C . PRO D 4 186 ? -48.101 11.465 -50.813 1.00 81.10 ? 182 PRO L C 1 ATOM 7110 O O . PRO D 4 186 ? -49.332 11.468 -50.847 1.00 83.36 ? 182 PRO L O 1 ATOM 7111 C CB . PRO D 4 186 ? -46.872 12.712 -52.629 1.00 75.51 ? 182 PRO L CB 1 ATOM 7112 C CG . PRO D 4 186 ? -45.643 13.564 -52.627 1.00 74.51 ? 182 PRO L CG 1 ATOM 7113 C CD . PRO D 4 186 ? -44.961 13.263 -51.293 1.00 81.23 ? 182 PRO L CD 1 ATOM 7114 N N . GLU D 4 187 ? -47.372 10.413 -50.443 1.00 81.62 ? 183 GLU L N 1 ATOM 7115 C CA . GLU D 4 187 ? -47.971 9.160 -49.994 1.00 88.99 ? 183 GLU L CA 1 ATOM 7116 C C . GLU D 4 187 ? -48.700 9.320 -48.656 1.00 95.28 ? 183 GLU L C 1 ATOM 7117 O O . GLU D 4 187 ? -49.784 8.766 -48.471 1.00 95.41 ? 183 GLU L O 1 ATOM 7118 C CB . GLU D 4 187 ? -46.920 8.046 -49.897 1.00 89.81 ? 183 GLU L CB 1 ATOM 7119 C CG . GLU D 4 187 ? -46.238 7.694 -51.224 1.00 102.64 ? 183 GLU L CG 1 ATOM 7120 C CD . GLU D 4 187 ? -44.822 8.261 -51.341 1.00 112.58 ? 183 GLU L CD 1 ATOM 7121 O OE1 . GLU D 4 187 ? -44.580 9.389 -50.854 1.00 104.97 ? 183 GLU L OE1 1 ATOM 7122 O OE2 . GLU D 4 187 ? -43.947 7.573 -51.915 1.00 112.05 ? 183 GLU L OE2 1 ATOM 7123 N N . GLN D 4 188 ? -48.112 10.071 -47.727 1.00 88.45 ? 184 GLN L N 1 ATOM 7124 C CA . GLN D 4 188 ? -48.768 10.340 -46.445 1.00 82.61 ? 184 GLN L CA 1 ATOM 7125 C C . GLN D 4 188 ? -50.011 11.210 -46.617 1.00 80.91 ? 184 GLN L C 1 ATOM 7126 O O . GLN D 4 188 ? -50.992 11.064 -45.886 1.00 81.29 ? 184 GLN L O 1 ATOM 7127 C CB . GLN D 4 188 ? -47.788 10.974 -45.460 1.00 81.69 ? 184 GLN L CB 1 ATOM 7128 C CG . GLN D 4 188 ? -46.799 9.979 -44.886 1.00 86.03 ? 184 GLN L CG 1 ATOM 7129 C CD . GLN D 4 188 ? -45.594 10.637 -44.239 1.00 90.08 ? 184 GLN L CD 1 ATOM 7130 O OE1 . GLN D 4 188 ? -44.907 11.459 -44.855 1.00 85.11 ? 184 GLN L OE1 1 ATOM 7131 N NE2 . GLN D 4 188 ? -45.325 10.268 -42.991 1.00 77.72 ? 184 GLN L NE2 1 ATOM 7132 N N . TRP D 4 189 ? -49.961 12.102 -47.600 1.00 85.79 ? 185 TRP L N 1 ATOM 7133 C CA . TRP D 4 189 ? -51.109 12.926 -47.979 1.00 86.33 ? 185 TRP L CA 1 ATOM 7134 C C . TRP D 4 189 ? -52.241 12.085 -48.587 1.00 90.03 ? 185 TRP L C 1 ATOM 7135 O O . TRP D 4 189 ? -53.422 12.396 -48.396 1.00 82.13 ? 185 TRP L O 1 ATOM 7136 C CB . TRP D 4 189 ? -50.653 14.014 -48.957 1.00 70.28 ? 185 TRP L CB 1 ATOM 7137 C CG . TRP D 4 189 ? -51.731 14.935 -49.533 1.00 68.08 ? 185 TRP L CG 1 ATOM 7138 C CD1 . TRP D 4 189 ? -51.925 15.236 -50.861 1.00 69.08 ? 185 TRP L CD1 1 ATOM 7139 C CD2 . TRP D 4 189 ? -52.721 15.694 -48.808 1.00 70.39 ? 185 TRP L CD2 1 ATOM 7140 N NE1 . TRP D 4 189 ? -52.975 16.119 -51.004 1.00 73.85 ? 185 TRP L NE1 1 ATOM 7141 C CE2 . TRP D 4 189 ? -53.482 16.415 -49.763 1.00 72.26 ? 185 TRP L CE2 1 ATOM 7142 C CE3 . TRP D 4 189 ? -53.045 15.826 -47.448 1.00 72.69 ? 185 TRP L CE3 1 ATOM 7143 C CZ2 . TRP D 4 189 ? -54.543 17.257 -49.400 1.00 70.18 ? 185 TRP L CZ2 1 ATOM 7144 C CZ3 . TRP D 4 189 ? -54.099 16.670 -47.087 1.00 69.33 ? 185 TRP L CZ3 1 ATOM 7145 C CH2 . TRP D 4 189 ? -54.832 17.372 -48.062 1.00 70.24 ? 185 TRP L CH2 1 ATOM 7146 N N . LYS D 4 190 ? -51.882 11.030 -49.321 1.00 91.03 ? 186 LYS L N 1 ATOM 7147 C CA . LYS D 4 190 ? -52.882 10.101 -49.852 1.00 94.24 ? 186 LYS L CA 1 ATOM 7148 C C . LYS D 4 190 ? -53.306 9.100 -48.772 1.00 96.96 ? 186 LYS L C 1 ATOM 7149 O O . LYS D 4 190 ? -54.463 8.677 -48.721 1.00 94.43 ? 186 LYS L O 1 ATOM 7150 C CB . LYS D 4 190 ? -52.364 9.360 -51.098 1.00 91.24 ? 186 LYS L CB 1 ATOM 7151 C CG . LYS D 4 190 ? -51.758 7.965 -50.828 1.00 95.87 ? 186 LYS L CG 1 ATOM 7152 C CD . LYS D 4 190 ? -51.748 7.070 -52.078 1.00 98.34 ? 186 LYS L CD 1 ATOM 7153 C CE . LYS D 4 190 ? -50.827 7.611 -53.169 1.00 96.63 ? 186 LYS L CE 1 ATOM 7154 N NZ . LYS D 4 190 ? -51.255 7.153 -54.524 1.00 93.55 ? 186 LYS L NZ 1 ATOM 7155 N N . SER D 4 191 ? -52.364 8.757 -47.895 1.00 94.01 ? 187 SER L N 1 ATOM 7156 C CA . SER D 4 191 ? -52.554 7.703 -46.906 1.00 92.47 ? 187 SER L CA 1 ATOM 7157 C C . SER D 4 191 ? -53.701 7.967 -45.928 1.00 99.23 ? 187 SER L C 1 ATOM 7158 O O . SER D 4 191 ? -54.199 7.033 -45.298 1.00 100.53 ? 187 SER L O 1 ATOM 7159 C CB . SER D 4 191 ? -51.252 7.463 -46.132 1.00 91.81 ? 187 SER L CB 1 ATOM 7160 O OG . SER D 4 191 ? -51.439 6.527 -45.087 1.00 92.94 ? 187 SER L OG 1 ATOM 7161 N N . HIS D 4 192 ? -54.113 9.229 -45.798 1.00 102.63 ? 188 HIS L N 1 ATOM 7162 C CA . HIS D 4 192 ? -55.179 9.602 -44.859 1.00 97.69 ? 188 HIS L CA 1 ATOM 7163 C C . HIS D 4 192 ? -56.297 10.377 -45.556 1.00 91.27 ? 188 HIS L C 1 ATOM 7164 O O . HIS D 4 192 ? -56.102 10.913 -46.649 1.00 87.96 ? 188 HIS L O 1 ATOM 7165 C CB . HIS D 4 192 ? -54.612 10.409 -43.683 1.00 93.38 ? 188 HIS L CB 1 ATOM 7166 C CG . HIS D 4 192 ? -53.484 9.726 -42.968 1.00 93.93 ? 188 HIS L CG 1 ATOM 7167 N ND1 . HIS D 4 192 ? -52.228 9.582 -43.522 1.00 93.45 ? 188 HIS L ND1 1 ATOM 7168 C CD2 . HIS D 4 192 ? -53.422 9.150 -41.743 1.00 95.74 ? 188 HIS L CD2 1 ATOM 7169 C CE1 . HIS D 4 192 ? -51.443 8.943 -42.669 1.00 95.23 ? 188 HIS L CE1 1 ATOM 7170 N NE2 . HIS D 4 192 ? -52.144 8.671 -41.582 1.00 99.74 ? 188 HIS L NE2 1 ATOM 7171 N N . ARG D 4 193 ? -57.467 10.436 -44.926 1.00 89.56 ? 189 ARG L N 1 ATOM 7172 C CA . ARG D 4 193 ? -58.631 11.042 -45.571 1.00 94.48 ? 189 ARG L CA 1 ATOM 7173 C C . ARG D 4 193 ? -58.815 12.471 -45.098 1.00 91.86 ? 189 ARG L C 1 ATOM 7174 O O . ARG D 4 193 ? -59.501 13.271 -45.742 1.00 89.38 ? 189 ARG L O 1 ATOM 7175 C CB . ARG D 4 193 ? -59.912 10.243 -45.297 1.00 98.09 ? 189 ARG L CB 1 ATOM 7176 C CG . ARG D 4 193 ? -59.688 8.873 -44.684 1.00 98.17 ? 189 ARG L CG 1 ATOM 7177 C CD . ARG D 4 193 ? -59.094 7.905 -45.690 1.00 101.92 ? 189 ARG L CD 1 ATOM 7178 N NE . ARG D 4 193 ? -58.154 6.997 -45.043 1.00 113.38 ? 189 ARG L NE 1 ATOM 7179 C CZ . ARG D 4 193 ? -57.114 6.436 -45.654 1.00 118.63 ? 189 ARG L CZ 1 ATOM 7180 N NH1 . ARG D 4 193 ? -56.871 6.696 -46.935 1.00 104.49 ? 189 ARG L NH1 1 ATOM 7181 N NH2 . ARG D 4 193 ? -56.312 5.617 -44.979 1.00 116.23 ? 189 ARG L NH2 1 ATOM 7182 N N . SER D 4 194 ? -58.193 12.787 -43.968 1.00 97.41 ? 190 SER L N 1 ATOM 7183 C CA . SER D 4 194 ? -58.337 14.111 -43.382 1.00 95.29 ? 190 SER L CA 1 ATOM 7184 C C . SER D 4 194 ? -57.107 14.582 -42.616 1.00 93.40 ? 190 SER L C 1 ATOM 7185 O O . SER D 4 194 ? -56.506 13.838 -41.826 1.00 88.44 ? 190 SER L O 1 ATOM 7186 C CB . SER D 4 194 ? -59.559 14.157 -42.466 1.00 96.01 ? 190 SER L CB 1 ATOM 7187 O OG . SER D 4 194 ? -59.678 15.424 -41.846 1.00 90.20 ? 190 SER L OG 1 ATOM 7188 N N . TYR D 4 195 ? -56.745 15.836 -42.865 1.00 93.04 ? 191 TYR L N 1 ATOM 7189 C CA . TYR D 4 195 ? -55.724 16.514 -42.079 1.00 90.14 ? 191 TYR L CA 1 ATOM 7190 C C . TYR D 4 195 ? -56.300 17.792 -41.471 1.00 81.41 ? 191 TYR L C 1 ATOM 7191 O O . TYR D 4 195 ? -57.081 18.505 -42.119 1.00 76.44 ? 191 TYR L O 1 ATOM 7192 C CB . TYR D 4 195 ? -54.491 16.813 -42.933 1.00 80.31 ? 191 TYR L CB 1 ATOM 7193 C CG . TYR D 4 195 ? -53.508 15.666 -43.008 1.00 75.58 ? 191 TYR L CG 1 ATOM 7194 C CD1 . TYR D 4 195 ? -53.343 14.931 -44.177 1.00 71.46 ? 191 TYR L CD1 1 ATOM 7195 C CD2 . TYR D 4 195 ? -52.743 15.319 -41.903 1.00 86.66 ? 191 TYR L CD2 1 ATOM 7196 C CE1 . TYR D 4 195 ? -52.430 13.882 -44.238 1.00 80.21 ? 191 TYR L CE1 1 ATOM 7197 C CE2 . TYR D 4 195 ? -51.833 14.280 -41.952 1.00 79.62 ? 191 TYR L CE2 1 ATOM 7198 C CZ . TYR D 4 195 ? -51.684 13.556 -43.112 1.00 86.00 ? 191 TYR L CZ 1 ATOM 7199 O OH . TYR D 4 195 ? -50.766 12.521 -43.137 1.00 83.93 ? 191 TYR L OH 1 ATOM 7200 N N . SER D 4 196 ? -55.920 18.071 -40.226 1.00 79.12 ? 192 SER L N 1 ATOM 7201 C CA . SER D 4 196 ? -56.468 19.216 -39.504 1.00 85.45 ? 192 SER L CA 1 ATOM 7202 C C . SER D 4 196 ? -55.446 20.051 -38.696 1.00 84.34 ? 192 SER L C 1 ATOM 7203 O O . SER D 4 196 ? -54.616 19.505 -37.956 1.00 77.91 ? 192 SER L O 1 ATOM 7204 C CB . SER D 4 196 ? -57.605 18.738 -38.599 1.00 84.96 ? 192 SER L CB 1 ATOM 7205 O OG . SER D 4 196 ? -58.622 18.117 -39.367 1.00 82.19 ? 192 SER L OG 1 ATOM 7206 N N . CYS D 4 197 ? -55.524 21.378 -38.839 1.00 74.58 ? 193 CYS L N 1 ATOM 7207 C CA . CYS D 4 197 ? -54.712 22.304 -38.036 1.00 75.29 ? 193 CYS L CA 1 ATOM 7208 C C . CYS D 4 197 ? -55.532 22.794 -36.837 1.00 69.04 ? 193 CYS L C 1 ATOM 7209 O O . CYS D 4 197 ? -56.593 23.395 -37.015 1.00 70.39 ? 193 CYS L O 1 ATOM 7210 C CB . CYS D 4 197 ? -54.227 23.495 -38.896 1.00 73.43 ? 193 CYS L CB 1 ATOM 7211 S SG . CYS D 4 197 ? -53.113 24.740 -38.081 1.00 75.52 ? 193 CYS L SG 1 ATOM 7212 N N . GLN D 4 198 ? -55.043 22.525 -35.625 1.00 70.65 ? 194 GLN L N 1 ATOM 7213 C CA . GLN D 4 198 ? -55.714 22.955 -34.392 1.00 77.52 ? 194 GLN L CA 1 ATOM 7214 C C . GLN D 4 198 ? -54.959 24.079 -33.688 1.00 71.51 ? 194 GLN L C 1 ATOM 7215 O O . GLN D 4 198 ? -53.855 23.869 -33.176 1.00 77.63 ? 194 GLN L O 1 ATOM 7216 C CB . GLN D 4 198 ? -55.856 21.790 -33.409 1.00 80.15 ? 194 GLN L CB 1 ATOM 7217 C CG . GLN D 4 198 ? -56.348 20.492 -34.012 1.00 89.49 ? 194 GLN L CG 1 ATOM 7218 C CD . GLN D 4 198 ? -56.997 19.589 -32.973 1.00 102.48 ? 194 GLN L CD 1 ATOM 7219 O OE1 . GLN D 4 198 ? -56.391 19.253 -31.952 1.00 101.80 ? 194 GLN L OE1 1 ATOM 7220 N NE2 . GLN D 4 198 ? -58.244 19.207 -33.224 1.00 103.89 ? 194 GLN L NE2 1 ATOM 7221 N N . VAL D 4 199 ? -55.567 25.260 -33.638 1.00 69.64 ? 195 VAL L N 1 ATOM 7222 C CA . VAL D 4 199 ? -54.967 26.418 -32.976 1.00 66.33 ? 195 VAL L CA 1 ATOM 7223 C C . VAL D 4 199 ? -55.714 26.772 -31.688 1.00 69.06 ? 195 VAL L C 1 ATOM 7224 O O . VAL D 4 199 ? -56.843 27.278 -31.733 1.00 72.98 ? 195 VAL L O 1 ATOM 7225 C CB . VAL D 4 199 ? -54.976 27.661 -33.900 1.00 67.31 ? 195 VAL L CB 1 ATOM 7226 C CG1 . VAL D 4 199 ? -54.384 28.877 -33.176 1.00 68.11 ? 195 VAL L CG1 1 ATOM 7227 C CG2 . VAL D 4 199 ? -54.225 27.364 -35.191 1.00 62.85 ? 195 VAL L CG2 1 ATOM 7228 N N . THR D 4 200 ? -55.085 26.510 -30.545 1.00 66.87 ? 196 THR L N 1 ATOM 7229 C CA . THR D 4 200 ? -55.669 26.883 -29.251 1.00 71.82 ? 196 THR L CA 1 ATOM 7230 C C . THR D 4 200 ? -55.176 28.258 -28.732 1.00 73.91 ? 196 THR L C 1 ATOM 7231 O O . THR D 4 200 ? -53.973 28.513 -28.652 1.00 74.07 ? 196 THR L O 1 ATOM 7232 C CB . THR D 4 200 ? -55.418 25.788 -28.212 1.00 64.47 ? 196 THR L CB 1 ATOM 7233 O OG1 . THR D 4 200 ? -54.052 25.829 -27.792 1.00 77.27 ? 196 THR L OG1 1 ATOM 7234 C CG2 . THR D 4 200 ? -55.699 24.441 -28.813 1.00 66.77 ? 196 THR L CG2 1 ATOM 7235 N N . HIS D 4 201 ? -56.112 29.144 -28.391 1.00 79.37 ? 197 HIS L N 1 ATOM 7236 C CA . HIS D 4 201 ? -55.784 30.510 -27.963 1.00 75.50 ? 197 HIS L CA 1 ATOM 7237 C C . HIS D 4 201 ? -56.603 30.886 -26.726 1.00 77.20 ? 197 HIS L C 1 ATOM 7238 O O . HIS D 4 201 ? -57.823 31.077 -26.822 1.00 77.45 ? 197 HIS L O 1 ATOM 7239 C CB . HIS D 4 201 ? -56.061 31.506 -29.105 1.00 65.91 ? 197 HIS L CB 1 ATOM 7240 C CG . HIS D 4 201 ? -55.841 32.949 -28.738 1.00 65.53 ? 197 HIS L CG 1 ATOM 7241 N ND1 . HIS D 4 201 ? -56.875 33.859 -28.636 1.00 60.05 ? 197 HIS L ND1 1 ATOM 7242 C CD2 . HIS D 4 201 ? -54.705 33.645 -28.479 1.00 58.87 ? 197 HIS L CD2 1 ATOM 7243 C CE1 . HIS D 4 201 ? -56.388 35.046 -28.316 1.00 61.10 ? 197 HIS L CE1 1 ATOM 7244 N NE2 . HIS D 4 201 ? -55.074 34.944 -28.215 1.00 63.98 ? 197 HIS L NE2 1 ATOM 7245 N N . GLU D 4 202 ? -55.932 31.006 -25.579 1.00 78.69 ? 198 GLU L N 1 ATOM 7246 C CA . GLU D 4 202 ? -56.600 31.236 -24.289 1.00 80.75 ? 198 GLU L CA 1 ATOM 7247 C C . GLU D 4 202 ? -57.678 30.174 -24.030 1.00 81.99 ? 198 GLU L C 1 ATOM 7248 O O . GLU D 4 202 ? -58.854 30.500 -23.851 1.00 81.96 ? 198 GLU L O 1 ATOM 7249 C CB . GLU D 4 202 ? -57.212 32.646 -24.210 1.00 56.80 ? 198 GLU L CB 1 ATOM 7250 C CG . GLU D 4 202 ? -56.251 33.788 -24.521 1.00 80.63 ? 198 GLU L CG 1 ATOM 7251 C CD . GLU D 4 202 ? -55.323 34.135 -23.358 1.00 90.51 ? 198 GLU L CD 1 ATOM 7252 O OE1 . GLU D 4 202 ? -55.774 34.119 -22.190 1.00 91.35 ? 198 GLU L OE1 1 ATOM 7253 O OE2 . GLU D 4 202 ? -54.135 34.430 -23.617 1.00 91.62 ? 198 GLU L OE2 1 ATOM 7254 N N . GLY D 4 203 ? -57.272 28.905 -24.038 1.00 84.59 ? 199 GLY L N 1 ATOM 7255 C CA . GLY D 4 203 ? -58.178 27.806 -23.745 1.00 87.99 ? 199 GLY L CA 1 ATOM 7256 C C . GLY D 4 203 ? -59.046 27.351 -24.906 1.00 87.33 ? 199 GLY L C 1 ATOM 7257 O O . GLY D 4 203 ? -59.179 26.154 -25.154 1.00 91.03 ? 199 GLY L O 1 ATOM 7258 N N . SER D 4 204 ? -59.640 28.308 -25.616 1.00 88.28 ? 200 SER L N 1 ATOM 7259 C CA . SER D 4 204 ? -60.509 28.016 -26.761 1.00 80.84 ? 200 SER L CA 1 ATOM 7260 C C . SER D 4 204 ? -59.709 27.602 -28.017 1.00 85.91 ? 200 SER L C 1 ATOM 7261 O O . SER D 4 204 ? -58.654 28.177 -28.311 1.00 76.20 ? 200 SER L O 1 ATOM 7262 C CB . SER D 4 204 ? -61.402 29.230 -27.061 1.00 85.48 ? 200 SER L CB 1 ATOM 7263 O OG . SER D 4 204 ? -61.823 29.877 -25.865 1.00 91.79 ? 200 SER L OG 1 ATOM 7264 N N . THR D 4 205 ? -60.218 26.606 -28.746 1.00 81.36 ? 201 THR L N 1 ATOM 7265 C CA . THR D 4 205 ? -59.531 26.039 -29.913 1.00 79.32 ? 201 THR L CA 1 ATOM 7266 C C . THR D 4 205 ? -60.242 26.323 -31.238 1.00 83.02 ? 201 THR L C 1 ATOM 7267 O O . THR D 4 205 ? -61.414 25.979 -31.407 1.00 89.54 ? 201 THR L O 1 ATOM 7268 C CB . THR D 4 205 ? -59.396 24.514 -29.790 1.00 78.53 ? 201 THR L CB 1 ATOM 7269 O OG1 . THR D 4 205 ? -58.729 24.188 -28.565 1.00 79.55 ? 201 THR L OG1 1 ATOM 7270 C CG2 . THR D 4 205 ? -58.610 23.946 -30.964 1.00 74.87 ? 201 THR L CG2 1 ATOM 7271 N N . VAL D 4 206 ? -59.532 26.953 -32.170 1.00 69.85 ? 202 VAL L N 1 ATOM 7272 C CA . VAL D 4 206 ? -60.033 27.123 -33.532 1.00 68.96 ? 202 VAL L CA 1 ATOM 7273 C C . VAL D 4 206 ? -59.507 25.967 -34.401 1.00 76.61 ? 202 VAL L C 1 ATOM 7274 O O . VAL D 4 206 ? -58.364 25.531 -34.246 1.00 70.12 ? 202 VAL L O 1 ATOM 7275 C CB . VAL D 4 206 ? -59.636 28.502 -34.130 1.00 65.08 ? 202 VAL L CB 1 ATOM 7276 C CG1 . VAL D 4 206 ? -60.309 28.728 -35.474 1.00 61.88 ? 202 VAL L CG1 1 ATOM 7277 C CG2 . VAL D 4 206 ? -60.012 29.625 -33.169 1.00 76.63 ? 202 VAL L CG2 1 ATOM 7278 N N . GLU D 4 207 ? -60.354 25.467 -35.299 1.00 81.98 ? 203 GLU L N 1 ATOM 7279 C CA . GLU D 4 207 ? -60.019 24.321 -36.143 1.00 75.82 ? 203 GLU L CA 1 ATOM 7280 C C . GLU D 4 207 ? -60.299 24.598 -37.623 1.00 74.93 ? 203 GLU L C 1 ATOM 7281 O O . GLU D 4 207 ? -61.256 25.305 -37.975 1.00 66.98 ? 203 GLU L O 1 ATOM 7282 C CB . GLU D 4 207 ? -60.837 23.106 -35.707 1.00 79.82 ? 203 GLU L CB 1 ATOM 7283 C CG . GLU D 4 207 ? -60.431 21.806 -36.353 1.00 83.74 ? 203 GLU L CG 1 ATOM 7284 C CD . GLU D 4 207 ? -59.454 21.037 -35.493 1.00 97.69 ? 203 GLU L CD 1 ATOM 7285 O OE1 . GLU D 4 207 ? -59.348 21.348 -34.287 1.00 100.25 ? 203 GLU L OE1 1 ATOM 7286 O OE2 . GLU D 4 207 ? -58.790 20.121 -36.018 1.00 94.78 ? 203 GLU L OE2 1 ATOM 7287 N N . LYS D 4 208 ? -59.438 24.061 -38.483 1.00 66.86 ? 204 LYS L N 1 ATOM 7288 C CA . LYS D 4 208 ? -59.744 23.932 -39.901 1.00 67.36 ? 204 LYS L CA 1 ATOM 7289 C C . LYS D 4 208 ? -59.207 22.594 -40.386 1.00 72.96 ? 204 LYS L C 1 ATOM 7290 O O . LYS D 4 208 ? -58.359 21.958 -39.733 1.00 66.81 ? 204 LYS L O 1 ATOM 7291 C CB . LYS D 4 208 ? -59.202 25.089 -40.755 1.00 61.07 ? 204 LYS L CB 1 ATOM 7292 C CG . LYS D 4 208 ? -59.753 26.460 -40.397 1.00 63.09 ? 204 LYS L CG 1 ATOM 7293 C CD . LYS D 4 208 ? -60.646 27.035 -41.473 1.00 68.69 ? 204 LYS L CD 1 ATOM 7294 C CE . LYS D 4 208 ? -61.318 28.322 -40.983 1.00 73.64 ? 204 LYS L CE 1 ATOM 7295 N NZ . LYS D 4 208 ? -61.594 29.301 -42.083 1.00 66.07 ? 204 LYS L NZ 1 ATOM 7296 N N . THR D 4 209 ? -59.718 22.170 -41.534 1.00 69.54 ? 205 THR L N 1 ATOM 7297 C CA . THR D 4 209 ? -59.442 20.841 -42.048 1.00 76.03 ? 205 THR L CA 1 ATOM 7298 C C . THR D 4 209 ? -59.430 20.866 -43.579 1.00 69.10 ? 205 THR L C 1 ATOM 7299 O O . THR D 4 209 ? -60.146 21.656 -44.199 1.00 75.02 ? 205 THR L O 1 ATOM 7300 C CB . THR D 4 209 ? -60.493 19.850 -41.506 1.00 80.50 ? 205 THR L CB 1 ATOM 7301 O OG1 . THR D 4 209 ? -60.350 19.749 -40.084 1.00 78.34 ? 205 THR L OG1 1 ATOM 7302 C CG2 . THR D 4 209 ? -60.337 18.467 -42.127 1.00 80.70 ? 205 THR L CG2 1 ATOM 7303 N N . VAL D 4 210 ? -58.566 20.047 -44.179 1.00 75.05 ? 206 VAL L N 1 ATOM 7304 C CA . VAL D 4 210 ? -58.587 19.828 -45.625 1.00 80.34 ? 206 VAL L CA 1 ATOM 7305 C C . VAL D 4 210 ? -58.530 18.329 -45.940 1.00 80.18 ? 206 VAL L C 1 ATOM 7306 O O . VAL D 4 210 ? -57.942 17.536 -45.187 1.00 74.01 ? 206 VAL L O 1 ATOM 7307 C CB . VAL D 4 210 ? -57.444 20.580 -46.385 1.00 80.17 ? 206 VAL L CB 1 ATOM 7308 C CG1 . VAL D 4 210 ? -57.655 22.101 -46.340 1.00 69.83 ? 206 VAL L CG1 1 ATOM 7309 C CG2 . VAL D 4 210 ? -56.059 20.169 -45.858 1.00 67.83 ? 206 VAL L CG2 1 ATOM 7310 N N . ALA D 4 211 ? -59.154 17.953 -47.052 1.00 76.12 ? 207 ALA L N 1 ATOM 7311 C CA . ALA D 4 211 ? -59.178 16.562 -47.493 1.00 84.37 ? 207 ALA L CA 1 ATOM 7312 C C . ALA D 4 211 ? -58.557 16.394 -48.892 1.00 77.96 ? 207 ALA L C 1 ATOM 7313 O O . ALA D 4 211 ? -58.809 17.196 -49.796 1.00 75.41 ? 207 ALA L O 1 ATOM 7314 C CB . ALA D 4 211 ? -60.607 16.028 -47.459 1.00 75.32 ? 207 ALA L CB 1 ATOM 7315 N N . PRO D 4 212 ? -57.721 15.353 -49.060 1.00 84.10 ? 208 PRO L N 1 ATOM 7316 C CA . PRO D 4 212 ? -57.103 15.025 -50.356 1.00 82.14 ? 208 PRO L CA 1 ATOM 7317 C C . PRO D 4 212 ? -58.104 14.474 -51.366 1.00 85.91 ? 208 PRO L C 1 ATOM 7318 O O . PRO D 4 212 ? -58.500 15.205 -52.275 1.00 83.80 ? 208 PRO L O 1 ATOM 7319 C CB . PRO D 4 212 ? -56.073 13.942 -49.997 1.00 77.35 ? 208 PRO L CB 1 ATOM 7320 C CG . PRO D 4 212 ? -56.557 13.357 -48.717 1.00 85.53 ? 208 PRO L CG 1 ATOM 7321 C CD . PRO D 4 212 ? -57.235 14.481 -47.973 1.00 79.93 ? 208 PRO L CD 1 HETATM 7322 C C1 . EDO E 5 . ? 5.046 67.281 -38.295 1.00 23.77 ? 401 EDO A C1 1 HETATM 7323 O O1 . EDO E 5 . ? 3.719 67.498 -38.794 1.00 20.05 ? 401 EDO A O1 1 HETATM 7324 C C2 . EDO E 5 . ? 5.022 66.273 -37.142 1.00 25.46 ? 401 EDO A C2 1 HETATM 7325 O O2 . EDO E 5 . ? 4.135 66.721 -36.121 1.00 19.58 ? 401 EDO A O2 1 HETATM 7326 C C1 . EDO F 5 . ? 0.007 64.936 -83.602 1.00 39.34 ? 402 EDO A C1 1 HETATM 7327 O O1 . EDO F 5 . ? 0.972 65.829 -84.226 1.00 40.97 ? 402 EDO A O1 1 HETATM 7328 C C2 . EDO F 5 . ? 0.716 63.794 -82.896 1.00 41.66 ? 402 EDO A C2 1 HETATM 7329 O O2 . EDO F 5 . ? 2.007 63.659 -83.563 1.00 45.23 ? 402 EDO A O2 1 HETATM 7330 C C1 . EDO G 5 . ? 3.236 68.768 -92.440 1.00 20.91 ? 403 EDO A C1 1 HETATM 7331 O O1 . EDO G 5 . ? 2.803 70.106 -92.431 1.00 37.33 ? 403 EDO A O1 1 HETATM 7332 C C2 . EDO G 5 . ? 3.993 68.262 -91.254 1.00 38.98 ? 403 EDO A C2 1 HETATM 7333 O O2 . EDO G 5 . ? 5.410 68.128 -91.483 1.00 45.30 ? 403 EDO A O2 1 HETATM 7334 C C1 . EDO H 5 . ? -14.125 55.727 -81.881 1.00 42.43 ? 404 EDO A C1 1 HETATM 7335 O O1 . EDO H 5 . ? -12.738 55.690 -81.865 1.00 36.61 ? 404 EDO A O1 1 HETATM 7336 C C2 . EDO H 5 . ? -14.703 55.781 -80.494 1.00 43.80 ? 404 EDO A C2 1 HETATM 7337 O O2 . EDO H 5 . ? -15.978 56.428 -80.620 1.00 33.05 ? 404 EDO A O2 1 HETATM 7338 C C1 . NAG I 6 . ? 2.403 51.051 -19.344 1.00 52.42 ? 405 NAG A C1 1 HETATM 7339 C C2 . NAG I 6 . ? 1.034 50.726 -18.753 1.00 56.28 ? 405 NAG A C2 1 HETATM 7340 C C3 . NAG I 6 . ? 1.112 50.361 -17.270 1.00 65.68 ? 405 NAG A C3 1 HETATM 7341 C C4 . NAG I 6 . ? 2.244 49.363 -16.992 1.00 82.02 ? 405 NAG A C4 1 HETATM 7342 C C5 . NAG I 6 . ? 3.530 49.813 -17.690 1.00 78.64 ? 405 NAG A C5 1 HETATM 7343 C C6 . NAG I 6 . ? 4.682 48.833 -17.473 1.00 75.91 ? 405 NAG A C6 1 HETATM 7344 C C7 . NAG I 6 . ? -1.061 51.718 -19.417 1.00 54.16 ? 405 NAG A C7 1 HETATM 7345 C C8 . NAG I 6 . ? -1.953 52.920 -19.366 1.00 41.34 ? 405 NAG A C8 1 HETATM 7346 N N2 . NAG I 6 . ? 0.155 51.876 -18.885 1.00 53.88 ? 405 NAG A N2 1 HETATM 7347 O O3 . NAG I 6 . ? -0.151 49.893 -16.819 1.00 63.80 ? 405 NAG A O3 1 HETATM 7348 O O4 . NAG I 6 . ? 2.478 49.289 -15.599 1.00 77.93 ? 405 NAG A O4 1 HETATM 7349 O O5 . NAG I 6 . ? 3.297 49.988 -19.079 1.00 66.50 ? 405 NAG A O5 1 HETATM 7350 O O6 . NAG I 6 . ? 5.899 49.541 -17.572 1.00 86.34 ? 405 NAG A O6 1 HETATM 7351 O O7 . NAG I 6 . ? -1.458 50.662 -19.925 1.00 54.56 ? 405 NAG A O7 1 HETATM 7352 C C1 . EDO J 5 . ? -22.759 52.572 -90.257 1.00 42.38 ? 406 EDO A C1 1 HETATM 7353 O O1 . EDO J 5 . ? -23.495 53.267 -89.253 1.00 28.19 ? 406 EDO A O1 1 HETATM 7354 C C2 . EDO J 5 . ? -21.863 53.432 -91.126 1.00 36.08 ? 406 EDO A C2 1 HETATM 7355 O O2 . EDO J 5 . ? -22.529 53.591 -92.332 1.00 38.66 ? 406 EDO A O2 1 HETATM 7356 C C1 . NAG K 6 . ? -28.783 72.212 -92.406 1.00 38.87 ? 407 NAG A C1 1 HETATM 7357 C C2 . NAG K 6 . ? -28.812 73.668 -92.910 1.00 33.06 ? 407 NAG A C2 1 HETATM 7358 C C3 . NAG K 6 . ? -29.974 74.439 -92.290 1.00 49.29 ? 407 NAG A C3 1 HETATM 7359 C C4 . NAG K 6 . ? -31.306 73.717 -92.444 1.00 47.15 ? 407 NAG A C4 1 HETATM 7360 C C5 . NAG K 6 . ? -31.223 72.222 -92.090 1.00 44.65 ? 407 NAG A C5 1 HETATM 7361 C C6 . NAG K 6 . ? -32.421 71.527 -92.748 1.00 54.70 ? 407 NAG A C6 1 HETATM 7362 C C7 . NAG K 6 . ? -26.924 75.094 -93.518 1.00 34.43 ? 407 NAG A C7 1 HETATM 7363 C C8 . NAG K 6 . ? -25.842 75.992 -92.967 1.00 34.80 ? 407 NAG A C8 1 HETATM 7364 N N2 . NAG K 6 . ? -27.608 74.402 -92.621 1.00 36.92 ? 407 NAG A N2 1 HETATM 7365 O O3 . NAG K 6 . ? -30.023 75.741 -92.848 1.00 48.29 ? 407 NAG A O3 1 HETATM 7366 O O4 . NAG K 6 . ? -32.213 74.349 -91.564 1.00 60.43 ? 407 NAG A O4 1 HETATM 7367 O O5 . NAG K 6 . ? -30.053 71.605 -92.605 1.00 39.98 ? 407 NAG A O5 1 HETATM 7368 O O6 . NAG K 6 . ? -32.727 70.332 -92.083 1.00 72.97 ? 407 NAG A O6 1 HETATM 7369 O O7 . NAG K 6 . ? -27.140 74.995 -94.726 1.00 43.33 ? 407 NAG A O7 1 HETATM 7370 C C1 . NAG L 6 . ? -33.444 74.730 -92.231 1.00 74.98 ? 408 NAG A C1 1 HETATM 7371 C C2 . NAG L 6 . ? -34.570 74.875 -91.213 1.00 70.87 ? 408 NAG A C2 1 HETATM 7372 C C3 . NAG L 6 . ? -35.907 75.086 -91.919 1.00 79.41 ? 408 NAG A C3 1 HETATM 7373 C C4 . NAG L 6 . ? -35.800 76.218 -92.939 1.00 83.76 ? 408 NAG A C4 1 HETATM 7374 C C5 . NAG L 6 . ? -34.537 76.097 -93.791 1.00 80.84 ? 408 NAG A C5 1 HETATM 7375 C C6 . NAG L 6 . ? -34.369 77.345 -94.650 1.00 72.89 ? 408 NAG A C6 1 HETATM 7376 C C7 . NAG L 6 . ? -34.053 73.763 -89.123 1.00 80.14 ? 408 NAG A C7 1 HETATM 7377 C C8 . NAG L 6 . ? -34.053 72.491 -88.322 1.00 73.46 ? 408 NAG A C8 1 HETATM 7378 N N2 . NAG L 6 . ? -34.610 73.716 -90.341 1.00 74.16 ? 408 NAG A N2 1 HETATM 7379 O O3 . NAG L 6 . ? -36.897 75.416 -90.961 1.00 82.63 ? 408 NAG A O3 1 HETATM 7380 O O4 . NAG L 6 . ? -36.942 76.241 -93.783 1.00 93.53 ? 408 NAG A O4 1 HETATM 7381 O O5 . NAG L 6 . ? -33.376 75.910 -93.000 1.00 75.02 ? 408 NAG A O5 1 HETATM 7382 O O6 . NAG L 6 . ? -33.829 76.984 -95.903 1.00 67.41 ? 408 NAG A O6 1 HETATM 7383 O O7 . NAG L 6 . ? -33.548 74.785 -88.644 1.00 70.46 ? 408 NAG A O7 1 HETATM 7384 C C1 . NAG M 6 . ? 13.438 62.781 -34.864 1.00 64.87 ? 409 NAG A C1 1 HETATM 7385 C C2 . NAG M 6 . ? 14.880 63.296 -35.019 1.00 66.47 ? 409 NAG A C2 1 HETATM 7386 C C3 . NAG M 6 . ? 15.531 62.831 -36.322 1.00 73.47 ? 409 NAG A C3 1 HETATM 7387 C C4 . NAG M 6 . ? 15.401 61.329 -36.478 1.00 65.97 ? 409 NAG A C4 1 HETATM 7388 C C5 . NAG M 6 . ? 13.968 60.863 -36.236 1.00 72.36 ? 409 NAG A C5 1 HETATM 7389 C C6 . NAG M 6 . ? 13.961 59.330 -36.273 1.00 54.26 ? 409 NAG A C6 1 HETATM 7390 C C7 . NAG M 6 . ? 15.630 65.389 -33.958 1.00 75.42 ? 409 NAG A C7 1 HETATM 7391 C C8 . NAG M 6 . ? 15.969 66.833 -34.246 1.00 69.94 ? 409 NAG A C8 1 HETATM 7392 N N2 . NAG M 6 . ? 14.962 64.749 -34.933 1.00 68.76 ? 409 NAG A N2 1 HETATM 7393 O O3 . NAG M 6 . ? 16.907 63.146 -36.285 1.00 64.24 ? 409 NAG A O3 1 HETATM 7394 O O4 . NAG M 6 . ? 15.846 60.938 -37.766 1.00 79.94 ? 409 NAG A O4 1 HETATM 7395 O O5 . NAG M 6 . ? 13.449 61.366 -34.997 1.00 63.10 ? 409 NAG A O5 1 HETATM 7396 O O6 . NAG M 6 . ? 12.635 58.859 -36.355 1.00 84.48 ? 409 NAG A O6 1 HETATM 7397 O O7 . NAG M 6 . ? 15.954 64.862 -32.880 1.00 66.34 ? 409 NAG A O7 1 HETATM 7398 C C1 . GOL N 7 . ? 3.956 62.643 -5.364 1.00 64.32 ? 201 GOL B C1 1 HETATM 7399 O O1 . GOL N 7 . ? 5.036 62.489 -6.257 1.00 67.55 ? 201 GOL B O1 1 HETATM 7400 C C2 . GOL N 7 . ? 2.677 62.196 -6.060 1.00 60.06 ? 201 GOL B C2 1 HETATM 7401 O O2 . GOL N 7 . ? 1.710 61.698 -5.142 1.00 60.83 ? 201 GOL B O2 1 HETATM 7402 C C3 . GOL N 7 . ? 2.101 63.397 -6.790 1.00 54.29 ? 201 GOL B C3 1 HETATM 7403 O O3 . GOL N 7 . ? 1.378 62.870 -7.881 1.00 53.94 ? 201 GOL B O3 1 HETATM 7404 C C1 . EDO O 5 . ? -0.175 58.756 -7.540 1.00 46.34 ? 202 EDO B C1 1 HETATM 7405 O O1 . EDO O 5 . ? 0.629 57.571 -7.441 1.00 69.37 ? 202 EDO B O1 1 HETATM 7406 C C2 . EDO O 5 . ? -0.141 59.421 -6.183 1.00 46.86 ? 202 EDO B C2 1 HETATM 7407 O O2 . EDO O 5 . ? -0.499 60.781 -6.395 1.00 54.61 ? 202 EDO B O2 1 HETATM 7408 C C1 . EDO P 5 . ? -20.717 72.308 -23.072 1.00 89.52 ? 203 EDO B C1 1 HETATM 7409 O O1 . EDO P 5 . ? -20.975 71.565 -24.274 1.00 70.59 ? 203 EDO B O1 1 HETATM 7410 C C2 . EDO P 5 . ? -21.991 72.359 -22.236 1.00 100.09 ? 203 EDO B C2 1 HETATM 7411 O O2 . EDO P 5 . ? -22.412 71.020 -21.935 1.00 101.66 ? 203 EDO B O2 1 HETATM 7412 C C1 . EDO Q 5 . ? -19.896 67.763 -25.353 1.00 36.74 ? 204 EDO B C1 1 HETATM 7413 O O1 . EDO Q 5 . ? -19.489 69.090 -25.031 1.00 36.99 ? 204 EDO B O1 1 HETATM 7414 C C2 . EDO Q 5 . ? -21.151 67.491 -24.521 1.00 35.41 ? 204 EDO B C2 1 HETATM 7415 O O2 . EDO Q 5 . ? -20.797 66.773 -23.325 1.00 47.20 ? 204 EDO B O2 1 HETATM 7416 C C1 . EDO R 5 . ? -16.693 69.986 -30.978 1.00 37.95 ? 205 EDO B C1 1 HETATM 7417 O O1 . EDO R 5 . ? -17.602 69.951 -32.109 1.00 36.85 ? 205 EDO B O1 1 HETATM 7418 C C2 . EDO R 5 . ? -17.482 70.397 -29.740 1.00 38.21 ? 205 EDO B C2 1 HETATM 7419 O O2 . EDO R 5 . ? -17.941 71.737 -29.953 1.00 43.86 ? 205 EDO B O2 1 HETATM 7420 C C1 . EDO S 5 . ? -16.163 66.990 -12.859 1.00 44.94 ? 206 EDO B C1 1 HETATM 7421 O O1 . EDO S 5 . ? -15.394 68.087 -13.412 1.00 38.74 ? 206 EDO B O1 1 HETATM 7422 C C2 . EDO S 5 . ? -15.385 65.845 -12.216 1.00 33.94 ? 206 EDO B C2 1 HETATM 7423 O O2 . EDO S 5 . ? -15.533 66.033 -10.768 1.00 47.44 ? 206 EDO B O2 1 HETATM 7424 C C1 . NAG T 6 . ? -20.792 67.966 -5.421 1.00 40.01 ? 207 NAG B C1 1 HETATM 7425 C C2 . NAG T 6 . ? -22.264 67.730 -5.827 1.00 60.07 ? 207 NAG B C2 1 HETATM 7426 C C3 . NAG T 6 . ? -23.205 67.557 -4.633 1.00 58.97 ? 207 NAG B C3 1 HETATM 7427 C C4 . NAG T 6 . ? -22.682 66.587 -3.587 1.00 63.81 ? 207 NAG B C4 1 HETATM 7428 C C5 . NAG T 6 . ? -21.215 66.889 -3.276 1.00 41.13 ? 207 NAG B C5 1 HETATM 7429 C C6 . NAG T 6 . ? -20.635 65.689 -2.539 1.00 42.25 ? 207 NAG B C6 1 HETATM 7430 C C7 . NAG T 6 . ? -22.772 68.948 -7.930 1.00 66.42 ? 207 NAG B C7 1 HETATM 7431 C C8 . NAG T 6 . ? -23.228 70.297 -8.444 1.00 57.42 ? 207 NAG B C8 1 HETATM 7432 N N2 . NAG T 6 . ? -22.793 68.844 -6.600 1.00 60.73 ? 207 NAG B N2 1 HETATM 7433 O O3 . NAG T 6 . ? -24.432 67.054 -5.098 1.00 67.14 ? 207 NAG B O3 1 HETATM 7434 O O4 . NAG T 6 . ? -23.497 66.636 -2.415 1.00 61.36 ? 207 NAG B O4 1 HETATM 7435 O O5 . NAG T 6 . ? -20.408 67.055 -4.433 1.00 40.64 ? 207 NAG B O5 1 HETATM 7436 O O6 . NAG T 6 . ? -20.356 66.134 -1.248 1.00 54.50 ? 207 NAG B O6 1 HETATM 7437 O O7 . NAG T 6 . ? -22.412 68.032 -8.692 1.00 61.10 ? 207 NAG B O7 1 HETATM 7438 C C1 . EDO U 5 . ? -15.990 60.502 -17.414 1.00 31.36 ? 301 EDO H C1 1 HETATM 7439 O O1 . EDO U 5 . ? -17.337 61.057 -17.316 1.00 32.64 ? 301 EDO H O1 1 HETATM 7440 C C2 . EDO U 5 . ? -15.085 60.554 -16.194 1.00 29.05 ? 301 EDO H C2 1 HETATM 7441 O O2 . EDO U 5 . ? -15.784 60.476 -14.901 1.00 42.32 ? 301 EDO H O2 1 HETATM 7442 O O . HOH V 8 . ? -14.107 63.610 -90.042 1.00 25.36 ? 501 HOH A O 1 HETATM 7443 O O . HOH V 8 . ? -15.123 59.317 -97.495 1.00 26.61 ? 502 HOH A O 1 HETATM 7444 O O . HOH V 8 . ? 1.281 68.822 -22.797 1.00 22.64 ? 503 HOH A O 1 HETATM 7445 O O . HOH V 8 . ? 0.338 65.703 -8.157 1.00 26.08 ? 504 HOH A O 1 HETATM 7446 O O . HOH V 8 . ? 9.500 63.904 -25.741 1.00 34.56 ? 505 HOH A O 1 HETATM 7447 O O . HOH V 8 . ? 1.747 62.604 -19.645 1.00 22.13 ? 506 HOH A O 1 HETATM 7448 O O . HOH V 8 . ? -2.963 73.471 -79.983 1.00 19.93 ? 507 HOH A O 1 HETATM 7449 O O . HOH V 8 . ? -6.579 79.080 -94.583 1.00 35.30 ? 508 HOH A O 1 HETATM 7450 O O . HOH V 8 . ? -7.944 52.117 -86.014 1.00 33.35 ? 509 HOH A O 1 HETATM 7451 O O . HOH V 8 . ? -7.681 54.453 -99.918 1.00 29.06 ? 510 HOH A O 1 HETATM 7452 O O . HOH V 8 . ? -10.038 73.806 -84.859 1.00 33.13 ? 511 HOH A O 1 HETATM 7453 O O . HOH V 8 . ? -7.161 72.395 -87.165 1.00 28.72 ? 512 HOH A O 1 HETATM 7454 O O . HOH V 8 . ? 2.445 61.822 -41.636 1.00 21.88 ? 513 HOH A O 1 HETATM 7455 O O . HOH V 8 . ? -16.498 56.987 -78.209 1.00 26.09 ? 514 HOH A O 1 HETATM 7456 O O . HOH V 8 . ? 3.350 70.559 -21.944 1.00 32.55 ? 515 HOH A O 1 HETATM 7457 O O . HOH V 8 . ? -7.015 56.025 -97.770 1.00 29.41 ? 516 HOH A O 1 HETATM 7458 O O . HOH V 8 . ? -1.081 63.288 -65.968 1.00 33.79 ? 517 HOH A O 1 HETATM 7459 O O . HOH V 8 . ? -18.076 55.211 -81.531 1.00 23.56 ? 518 HOH A O 1 HETATM 7460 O O . HOH V 8 . ? -0.800 55.784 -74.947 1.00 28.01 ? 519 HOH A O 1 HETATM 7461 O O . HOH V 8 . ? -15.921 61.480 -106.673 1.00 36.96 ? 520 HOH A O 1 HETATM 7462 O O . HOH V 8 . ? -9.848 51.369 -72.242 1.00 33.30 ? 521 HOH A O 1 HETATM 7463 O O . HOH V 8 . ? 4.217 70.109 -39.752 1.00 22.38 ? 522 HOH A O 1 HETATM 7464 O O . HOH V 8 . ? 3.708 58.653 -100.150 1.00 35.69 ? 523 HOH A O 1 HETATM 7465 O O . HOH V 8 . ? -20.062 75.168 -86.837 1.00 27.84 ? 524 HOH A O 1 HETATM 7466 O O . HOH V 8 . ? -5.072 65.740 -55.176 1.00 26.58 ? 525 HOH A O 1 HETATM 7467 O O . HOH V 8 . ? -7.922 71.468 -111.529 1.00 43.62 ? 526 HOH A O 1 HETATM 7468 O O . HOH V 8 . ? -0.432 62.633 -78.128 1.00 26.77 ? 527 HOH A O 1 HETATM 7469 O O . HOH V 8 . ? 3.849 58.545 -50.469 1.00 28.73 ? 528 HOH A O 1 HETATM 7470 O O . HOH V 8 . ? -9.631 73.895 -77.246 1.00 27.01 ? 529 HOH A O 1 HETATM 7471 O O . HOH V 8 . ? -2.887 58.603 -36.496 1.00 29.19 ? 530 HOH A O 1 HETATM 7472 O O . HOH V 8 . ? -11.234 55.780 -53.397 1.00 32.77 ? 531 HOH A O 1 HETATM 7473 O O . HOH V 8 . ? -14.485 53.158 -70.729 1.00 29.80 ? 532 HOH A O 1 HETATM 7474 O O . HOH V 8 . ? -8.236 55.241 -95.424 1.00 27.80 ? 533 HOH A O 1 HETATM 7475 O O . HOH V 8 . ? -0.376 56.819 -44.941 1.00 34.25 ? 534 HOH A O 1 HETATM 7476 O O . HOH V 8 . ? -4.681 55.027 -50.417 1.00 26.85 ? 535 HOH A O 1 HETATM 7477 O O . HOH V 8 . ? -15.686 51.255 -92.312 1.00 27.12 ? 536 HOH A O 1 HETATM 7478 O O . HOH V 8 . ? 12.490 56.210 -92.523 1.00 44.04 ? 537 HOH A O 1 HETATM 7479 O O . HOH V 8 . ? -9.277 73.795 -88.942 1.00 28.51 ? 538 HOH A O 1 HETATM 7480 O O . HOH V 8 . ? -16.581 48.498 -82.650 1.00 33.21 ? 539 HOH A O 1 HETATM 7481 O O . HOH V 8 . ? -16.856 75.025 -87.760 1.00 26.79 ? 540 HOH A O 1 HETATM 7482 O O . HOH V 8 . ? -10.431 60.966 6.674 1.00 31.83 ? 541 HOH A O 1 HETATM 7483 O O . HOH V 8 . ? -5.588 66.785 -62.477 1.00 32.85 ? 542 HOH A O 1 HETATM 7484 O O . HOH V 8 . ? -4.234 48.139 -78.714 1.00 35.66 ? 543 HOH A O 1 HETATM 7485 O O . HOH V 8 . ? -18.866 77.185 -85.421 1.00 35.41 ? 544 HOH A O 1 HETATM 7486 O O . HOH V 8 . ? 7.828 67.201 -44.841 1.00 39.82 ? 545 HOH A O 1 HETATM 7487 O O . HOH V 8 . ? -0.186 53.529 -70.213 1.00 30.50 ? 546 HOH A O 1 HETATM 7488 O O . HOH V 8 . ? -18.736 53.261 -97.822 1.00 35.89 ? 547 HOH A O 1 HETATM 7489 O O . HOH V 8 . ? -10.079 60.523 -51.189 1.00 38.42 ? 548 HOH A O 1 HETATM 7490 O O . HOH V 8 . ? -13.805 49.214 -77.351 1.00 43.90 ? 549 HOH A O 1 HETATM 7491 O O . HOH V 8 . ? -6.503 61.671 -30.766 1.00 26.69 ? 550 HOH A O 1 HETATM 7492 O O . HOH V 8 . ? -3.731 72.582 -111.307 1.00 45.64 ? 551 HOH A O 1 HETATM 7493 O O . HOH V 8 . ? -18.893 54.020 -79.179 1.00 39.00 ? 552 HOH A O 1 HETATM 7494 O O . HOH V 8 . ? -7.433 56.139 -103.101 1.00 29.80 ? 553 HOH A O 1 HETATM 7495 O O . HOH V 8 . ? -1.773 49.833 -78.564 1.00 33.12 ? 554 HOH A O 1 HETATM 7496 O O . HOH V 8 . ? -5.111 48.304 -81.385 1.00 35.90 ? 555 HOH A O 1 HETATM 7497 O O . HOH V 8 . ? -22.421 55.543 -101.755 1.00 40.32 ? 556 HOH A O 1 HETATM 7498 O O . HOH V 8 . ? -4.409 58.097 -34.399 1.00 37.71 ? 557 HOH A O 1 HETATM 7499 O O . HOH V 8 . ? 4.171 60.274 -40.162 1.00 37.21 ? 558 HOH A O 1 HETATM 7500 O O . HOH V 8 . ? -17.134 58.487 -62.722 1.00 38.65 ? 559 HOH A O 1 HETATM 7501 O O . HOH V 8 . ? 1.187 50.011 -54.211 1.00 52.58 ? 560 HOH A O 1 HETATM 7502 O O . HOH V 8 . ? -12.046 52.811 -92.710 1.00 32.51 ? 561 HOH A O 1 HETATM 7503 O O . HOH V 8 . ? 5.036 64.383 -17.594 1.00 30.62 ? 562 HOH A O 1 HETATM 7504 O O . HOH V 8 . ? -2.820 76.079 -80.904 1.00 33.69 ? 563 HOH A O 1 HETATM 7505 O O . HOH V 8 . ? -22.956 55.963 -89.121 1.00 36.93 ? 564 HOH A O 1 HETATM 7506 O O . HOH V 8 . ? -6.822 63.581 -102.697 1.00 29.49 ? 565 HOH A O 1 HETATM 7507 O O . HOH V 8 . ? 2.172 61.733 -78.874 1.00 40.16 ? 566 HOH A O 1 HETATM 7508 O O . HOH V 8 . ? -8.140 51.920 -98.625 1.00 33.77 ? 567 HOH A O 1 HETATM 7509 O O . HOH V 8 . ? 4.638 53.191 -89.099 1.00 42.07 ? 568 HOH A O 1 HETATM 7510 O O . HOH V 8 . ? 7.176 64.680 -51.522 1.00 44.19 ? 569 HOH A O 1 HETATM 7511 O O . HOH V 8 . ? -20.634 53.382 -73.531 1.00 29.43 ? 570 HOH A O 1 HETATM 7512 O O . HOH V 8 . ? -10.188 58.039 -51.283 1.00 39.81 ? 571 HOH A O 1 HETATM 7513 O O . HOH V 8 . ? -9.998 63.757 -48.234 1.00 43.38 ? 572 HOH A O 1 HETATM 7514 O O . HOH V 8 . ? 6.526 56.353 -23.852 1.00 42.40 ? 573 HOH A O 1 HETATM 7515 O O . HOH V 8 . ? 5.515 62.873 -88.145 1.00 32.71 ? 574 HOH A O 1 HETATM 7516 O O . HOH V 8 . ? -7.374 49.603 -73.631 1.00 36.60 ? 575 HOH A O 1 HETATM 7517 O O . HOH V 8 . ? -10.097 69.448 -111.366 1.00 37.45 ? 576 HOH A O 1 HETATM 7518 O O . HOH V 8 . ? 0.086 51.251 -89.261 1.00 35.46 ? 577 HOH A O 1 HETATM 7519 O O . HOH V 8 . ? 5.037 59.674 -54.666 1.00 34.20 ? 578 HOH A O 1 HETATM 7520 O O . HOH V 8 . ? 5.852 56.023 -73.214 1.00 32.72 ? 579 HOH A O 1 HETATM 7521 O O . HOH V 8 . ? 1.977 68.760 -81.280 1.00 38.28 ? 580 HOH A O 1 HETATM 7522 O O . HOH V 8 . ? -2.766 69.165 -57.011 1.00 30.51 ? 581 HOH A O 1 HETATM 7523 O O . HOH V 8 . ? 15.319 69.882 -103.396 1.00 36.87 ? 582 HOH A O 1 HETATM 7524 O O . HOH V 8 . ? 5.427 60.143 -87.600 1.00 37.83 ? 583 HOH A O 1 HETATM 7525 O O . HOH V 8 . ? 2.015 53.268 -86.048 1.00 30.53 ? 584 HOH A O 1 HETATM 7526 O O . HOH V 8 . ? -23.368 65.525 -71.549 1.00 40.37 ? 585 HOH A O 1 HETATM 7527 O O . HOH V 8 . ? -14.956 60.113 -57.326 1.00 37.91 ? 586 HOH A O 1 HETATM 7528 O O . HOH V 8 . ? 8.837 69.133 -38.714 1.00 34.11 ? 587 HOH A O 1 HETATM 7529 O O . HOH V 8 . ? 8.957 58.494 -28.598 1.00 33.32 ? 588 HOH A O 1 HETATM 7530 O O . HOH V 8 . ? 9.494 59.218 -99.878 1.00 39.38 ? 589 HOH A O 1 HETATM 7531 O O . HOH V 8 . ? -22.078 63.713 -97.194 1.00 43.23 ? 590 HOH A O 1 HETATM 7532 O O . HOH V 8 . ? 2.354 50.308 -59.936 1.00 38.51 ? 591 HOH A O 1 HETATM 7533 O O . HOH V 8 . ? 4.141 55.786 -65.439 1.00 36.33 ? 592 HOH A O 1 HETATM 7534 O O . HOH V 8 . ? -25.735 66.534 -95.411 1.00 38.15 ? 593 HOH A O 1 HETATM 7535 O O . HOH V 8 . ? -6.039 66.735 -69.718 1.00 35.50 ? 594 HOH A O 1 HETATM 7536 O O . HOH V 8 . ? 11.414 56.985 -89.108 1.00 37.46 ? 595 HOH A O 1 HETATM 7537 O O . HOH V 8 . ? 0.886 69.904 -84.004 1.00 35.37 ? 596 HOH A O 1 HETATM 7538 O O . HOH V 8 . ? -18.202 52.584 -69.964 1.00 36.14 ? 597 HOH A O 1 HETATM 7539 O O . HOH V 8 . ? -7.426 52.898 -94.262 1.00 31.80 ? 598 HOH A O 1 HETATM 7540 O O . HOH V 8 . ? 3.092 53.259 -59.534 1.00 34.51 ? 599 HOH A O 1 HETATM 7541 O O . HOH V 8 . ? 4.862 58.081 -19.824 1.00 35.87 ? 600 HOH A O 1 HETATM 7542 O O . HOH V 8 . ? -14.755 61.548 -64.869 1.00 37.99 ? 601 HOH A O 1 HETATM 7543 O O . HOH V 8 . ? 5.550 67.125 -56.686 1.00 39.05 ? 602 HOH A O 1 HETATM 7544 O O . HOH V 8 . ? 6.852 67.555 -42.283 1.00 40.17 ? 603 HOH A O 1 HETATM 7545 O O . HOH V 8 . ? -8.910 67.689 -47.795 1.00 36.42 ? 604 HOH A O 1 HETATM 7546 O O . HOH V 8 . ? 4.102 58.667 -68.157 1.00 44.45 ? 605 HOH A O 1 HETATM 7547 O O . HOH V 8 . ? -17.199 51.634 -67.668 1.00 32.63 ? 606 HOH A O 1 HETATM 7548 O O . HOH V 8 . ? -14.243 52.302 -94.374 1.00 34.45 ? 607 HOH A O 1 HETATM 7549 O O . HOH V 8 . ? -1.038 73.964 -94.617 1.00 48.14 ? 608 HOH A O 1 HETATM 7550 O O . HOH V 8 . ? -18.329 72.595 -101.347 1.00 35.55 ? 609 HOH A O 1 HETATM 7551 O O . HOH V 8 . ? -4.548 68.797 -54.529 1.00 33.78 ? 610 HOH A O 1 HETATM 7552 O O . HOH V 8 . ? 8.446 57.184 -73.035 1.00 44.35 ? 611 HOH A O 1 HETATM 7553 O O . HOH V 8 . ? -7.859 54.926 -112.352 1.00 44.50 ? 612 HOH A O 1 HETATM 7554 O O . HOH V 8 . ? 6.000 53.916 -75.152 1.00 39.65 ? 613 HOH A O 1 HETATM 7555 O O . HOH V 8 . ? -16.131 65.683 -108.299 1.00 37.88 ? 614 HOH A O 1 HETATM 7556 O O . HOH V 8 . ? 4.984 62.290 -57.278 1.00 37.94 ? 615 HOH A O 1 HETATM 7557 O O . HOH V 8 . ? 6.606 59.897 -99.299 1.00 39.10 ? 616 HOH A O 1 HETATM 7558 O O . HOH V 8 . ? 5.931 59.959 -42.518 1.00 44.71 ? 617 HOH A O 1 HETATM 7559 O O . HOH V 8 . ? 16.024 60.660 -95.734 1.00 44.02 ? 618 HOH A O 1 HETATM 7560 O O . HOH V 8 . ? 1.310 67.425 -77.373 1.00 44.09 ? 619 HOH A O 1 HETATM 7561 O O . HOH V 8 . ? -10.402 65.041 -44.394 1.00 32.66 ? 620 HOH A O 1 HETATM 7562 O O . HOH V 8 . ? -14.299 69.373 -112.281 1.00 46.10 ? 621 HOH A O 1 HETATM 7563 O O . HOH V 8 . ? -0.301 63.590 4.570 1.00 36.82 ? 622 HOH A O 1 HETATM 7564 O O . HOH V 8 . ? -18.359 59.200 -67.825 1.00 41.39 ? 623 HOH A O 1 HETATM 7565 O O . HOH V 8 . ? -5.001 60.195 5.716 1.00 48.10 ? 624 HOH A O 1 HETATM 7566 O O . HOH V 8 . ? -15.893 55.166 -103.932 1.00 37.66 ? 625 HOH A O 1 HETATM 7567 O O . HOH V 8 . ? 3.732 49.975 -84.313 1.00 43.62 ? 626 HOH A O 1 HETATM 7568 O O . HOH V 8 . ? -11.553 50.243 -76.077 1.00 40.72 ? 627 HOH A O 1 HETATM 7569 O O . HOH V 8 . ? 10.791 62.013 -27.732 1.00 44.93 ? 628 HOH A O 1 HETATM 7570 O O . HOH V 8 . ? 8.926 65.739 -40.880 1.00 41.78 ? 629 HOH A O 1 HETATM 7571 O O . HOH V 8 . ? -1.828 56.931 -109.547 1.00 46.76 ? 630 HOH A O 1 HETATM 7572 O O . HOH V 8 . ? -3.929 55.457 -23.203 1.00 30.60 ? 631 HOH A O 1 HETATM 7573 O O . HOH V 8 . ? -23.236 53.718 -95.586 1.00 35.72 ? 632 HOH A O 1 HETATM 7574 O O . HOH V 8 . ? -26.817 65.418 -93.067 1.00 37.01 ? 633 HOH A O 1 HETATM 7575 O O . HOH V 8 . ? -6.874 51.608 -96.199 1.00 39.30 ? 634 HOH A O 1 HETATM 7576 O O . HOH V 8 . ? -16.582 81.288 -92.090 1.00 36.43 ? 635 HOH A O 1 HETATM 7577 O O . HOH V 8 . ? 14.026 69.587 -30.757 1.00 34.39 ? 636 HOH A O 1 HETATM 7578 O O . HOH V 8 . ? 2.410 64.224 -1.517 1.00 34.75 ? 637 HOH A O 1 HETATM 7579 O O . HOH V 8 . ? -6.005 52.673 -53.126 1.00 39.10 ? 638 HOH A O 1 HETATM 7580 O O . HOH V 8 . ? -2.313 54.095 -72.022 1.00 32.22 ? 639 HOH A O 1 HETATM 7581 O O . HOH V 8 . ? -12.283 55.540 -94.457 1.00 40.37 ? 640 HOH A O 1 HETATM 7582 O O . HOH V 8 . ? 4.464 54.346 -61.548 1.00 45.95 ? 641 HOH A O 1 HETATM 7583 O O . HOH V 8 . ? -3.489 63.182 -64.389 1.00 37.09 ? 642 HOH A O 1 HETATM 7584 O O . HOH V 8 . ? -8.448 56.992 -44.382 1.00 42.44 ? 643 HOH A O 1 HETATM 7585 O O . HOH V 8 . ? 9.631 66.141 -110.107 1.00 48.92 ? 644 HOH A O 1 HETATM 7586 O O . HOH V 8 . ? 0.128 48.355 -64.973 1.00 41.44 ? 645 HOH A O 1 HETATM 7587 O O . HOH V 8 . ? -12.253 51.503 -73.704 1.00 30.30 ? 646 HOH A O 1 HETATM 7588 O O . HOH V 8 . ? -4.030 70.273 -73.416 1.00 33.08 ? 647 HOH A O 1 HETATM 7589 O O . HOH V 8 . ? -17.614 65.791 -105.739 1.00 36.81 ? 648 HOH A O 1 HETATM 7590 O O . HOH V 8 . ? -13.538 53.796 -73.291 1.00 26.82 ? 649 HOH A O 1 HETATM 7591 O O . HOH V 8 . ? 3.020 56.187 -85.729 1.00 34.88 ? 650 HOH A O 1 HETATM 7592 O O . HOH V 8 . ? -13.734 74.473 -83.566 1.00 31.97 ? 651 HOH A O 1 HETATM 7593 O O . HOH V 8 . ? -13.404 74.265 -80.820 1.00 30.32 ? 652 HOH A O 1 HETATM 7594 O O . HOH V 8 . ? 4.011 62.043 -18.589 1.00 30.53 ? 653 HOH A O 1 HETATM 7595 O O . HOH V 8 . ? -22.697 68.109 -78.096 1.00 40.87 ? 654 HOH A O 1 HETATM 7596 O O . HOH V 8 . ? -0.353 53.028 -23.673 1.00 36.84 ? 655 HOH A O 1 HETATM 7597 O O . HOH V 8 . ? -0.325 71.504 -82.510 1.00 32.18 ? 656 HOH A O 1 HETATM 7598 O O . HOH V 8 . ? -6.225 48.936 -95.688 1.00 39.54 ? 657 HOH A O 1 HETATM 7599 O O . HOH V 8 . ? -25.199 75.885 -97.021 1.00 56.27 ? 658 HOH A O 1 HETATM 7600 O O . HOH V 8 . ? -2.232 52.122 -104.279 1.00 45.74 ? 659 HOH A O 1 HETATM 7601 O O . HOH V 8 . ? -8.880 53.005 -54.339 1.00 37.74 ? 660 HOH A O 1 HETATM 7602 O O . HOH V 8 . ? -12.276 52.333 -53.261 1.00 53.45 ? 661 HOH A O 1 HETATM 7603 O O . HOH V 8 . ? -12.988 51.971 -50.379 1.00 51.89 ? 662 HOH A O 1 HETATM 7604 O O . HOH V 8 . ? -4.818 65.989 -64.982 1.00 40.72 ? 663 HOH A O 1 HETATM 7605 O O . HOH V 8 . ? 3.092 56.174 -63.011 1.00 36.45 ? 664 HOH A O 1 HETATM 7606 O O . HOH V 8 . ? -1.811 53.273 -106.896 1.00 53.81 ? 665 HOH A O 1 HETATM 7607 O O . HOH V 8 . ? 6.066 55.132 -32.345 1.00 52.89 ? 666 HOH A O 1 HETATM 7608 O O . HOH V 8 . ? 8.005 64.052 -34.631 1.00 31.90 ? 667 HOH A O 1 HETATM 7609 O O . HOH V 8 . ? 4.551 61.699 -112.752 1.00 42.21 ? 668 HOH A O 1 HETATM 7610 O O . HOH V 8 . ? -7.846 74.494 -85.507 1.00 34.04 ? 669 HOH A O 1 HETATM 7611 O O . HOH V 8 . ? 5.720 59.054 -34.214 1.00 39.30 ? 670 HOH A O 1 HETATM 7612 O O . HOH V 8 . ? -11.032 80.236 -90.663 1.00 36.75 ? 671 HOH A O 1 HETATM 7613 O O . HOH V 8 . ? -10.234 48.051 -74.926 1.00 45.77 ? 672 HOH A O 1 HETATM 7614 O O . HOH V 8 . ? 3.147 56.038 -99.642 1.00 40.78 ? 673 HOH A O 1 HETATM 7615 O O . HOH V 8 . ? -27.565 56.568 -79.937 1.00 36.55 ? 674 HOH A O 1 HETATM 7616 O O . HOH V 8 . ? 5.083 65.299 -19.953 1.00 33.61 ? 675 HOH A O 1 HETATM 7617 O O . HOH V 8 . ? 2.613 63.742 -75.645 1.00 50.90 ? 676 HOH A O 1 HETATM 7618 O O . HOH V 8 . ? 5.103 63.950 -53.546 1.00 37.40 ? 677 HOH A O 1 HETATM 7619 O O . HOH V 8 . ? -3.099 49.072 -63.080 1.00 35.55 ? 678 HOH A O 1 HETATM 7620 O O . HOH V 8 . ? -11.271 55.489 -46.640 1.00 52.85 ? 679 HOH A O 1 HETATM 7621 O O . HOH V 8 . ? -12.781 53.587 -87.972 1.00 38.27 ? 680 HOH A O 1 HETATM 7622 O O . HOH V 8 . ? -19.424 83.828 -88.507 1.00 42.02 ? 681 HOH A O 1 HETATM 7623 O O . HOH V 8 . ? -7.820 48.874 -70.801 1.00 43.47 ? 682 HOH A O 1 HETATM 7624 O O . HOH V 8 . ? -13.664 55.224 -105.622 1.00 36.19 ? 683 HOH A O 1 HETATM 7625 O O . HOH V 8 . ? 7.425 64.190 -24.154 1.00 38.49 ? 684 HOH A O 1 HETATM 7626 O O . HOH V 8 . ? -0.304 48.536 -62.110 1.00 38.09 ? 685 HOH A O 1 HETATM 7627 O O . HOH V 8 . ? -1.061 61.817 -1.557 1.00 41.73 ? 686 HOH A O 1 HETATM 7628 O O . HOH V 8 . ? 5.993 59.897 -47.160 1.00 39.38 ? 687 HOH A O 1 HETATM 7629 O O . HOH V 8 . ? -0.496 53.676 -26.372 1.00 43.29 ? 688 HOH A O 1 HETATM 7630 O O . HOH V 8 . ? -25.420 62.662 -89.645 1.00 46.18 ? 689 HOH A O 1 HETATM 7631 O O . HOH V 8 . ? -3.668 76.665 -105.619 1.00 53.48 ? 690 HOH A O 1 HETATM 7632 O O . HOH V 8 . ? -7.723 66.458 -113.771 1.00 41.13 ? 691 HOH A O 1 HETATM 7633 O O . HOH V 8 . ? -10.243 53.025 -105.846 1.00 37.44 ? 692 HOH A O 1 HETATM 7634 O O . HOH V 8 . ? 1.313 62.637 -64.986 1.00 36.59 ? 693 HOH A O 1 HETATM 7635 O O . HOH V 8 . ? -8.923 65.395 -57.808 1.00 33.21 ? 694 HOH A O 1 HETATM 7636 O O . HOH V 8 . ? -8.376 46.547 -70.433 1.00 50.30 ? 695 HOH A O 1 HETATM 7637 O O . HOH V 8 . ? -15.237 75.188 -99.443 1.00 32.97 ? 696 HOH A O 1 HETATM 7638 O O . HOH V 8 . ? 4.988 55.486 -54.599 1.00 53.59 ? 697 HOH A O 1 HETATM 7639 O O . HOH V 8 . ? -4.828 57.280 -113.273 1.00 38.18 ? 698 HOH A O 1 HETATM 7640 O O . HOH V 8 . ? 1.966 44.255 -90.915 1.00 42.72 ? 699 HOH A O 1 HETATM 7641 O O . HOH V 8 . ? 0.700 45.764 -99.434 1.00 45.83 ? 700 HOH A O 1 HETATM 7642 O O . HOH V 8 . ? -3.058 47.346 -99.395 1.00 40.94 ? 701 HOH A O 1 HETATM 7643 O O . HOH V 8 . ? 1.418 59.181 -36.121 1.00 56.12 ? 702 HOH A O 1 HETATM 7644 O O . HOH V 8 . ? 14.516 66.725 -29.985 1.00 53.86 ? 703 HOH A O 1 HETATM 7645 O O . HOH V 8 . ? -17.092 69.911 -109.271 1.00 54.41 ? 704 HOH A O 1 HETATM 7646 O O . HOH V 8 . ? 9.502 69.652 -56.231 1.00 58.05 ? 705 HOH A O 1 HETATM 7647 O O . HOH V 8 . ? -11.155 66.372 -54.830 1.00 44.43 ? 706 HOH A O 1 HETATM 7648 O O . HOH V 8 . ? -16.022 49.163 -61.177 1.00 49.11 ? 707 HOH A O 1 HETATM 7649 O O . HOH V 8 . ? -11.801 65.582 -60.193 1.00 39.98 ? 708 HOH A O 1 HETATM 7650 O O . HOH V 8 . ? -26.221 75.353 -83.490 1.00 41.14 ? 709 HOH A O 1 HETATM 7651 O O . HOH V 8 . ? -0.640 73.617 -84.269 1.00 44.58 ? 710 HOH A O 1 HETATM 7652 O O . HOH V 8 . ? 4.329 61.792 -63.442 1.00 44.94 ? 711 HOH A O 1 HETATM 7653 O O . HOH V 8 . ? -14.945 55.860 -108.792 1.00 44.19 ? 712 HOH A O 1 HETATM 7654 O O . HOH V 8 . ? 3.275 60.323 -64.910 1.00 49.04 ? 713 HOH A O 1 HETATM 7655 O O . HOH V 8 . ? -3.066 56.256 -44.133 1.00 46.53 ? 714 HOH A O 1 HETATM 7656 O O . HOH V 8 . ? 8.803 53.017 -88.878 1.00 54.26 ? 715 HOH A O 1 HETATM 7657 O O . HOH V 8 . ? -8.547 68.022 -66.658 1.00 48.86 ? 716 HOH A O 1 HETATM 7658 O O . HOH V 8 . ? -16.139 77.888 -105.473 1.00 51.18 ? 717 HOH A O 1 HETATM 7659 O O . HOH V 8 . ? -27.140 59.830 -80.765 1.00 42.34 ? 718 HOH A O 1 HETATM 7660 O O . HOH V 8 . ? -11.497 47.929 -56.329 1.00 48.27 ? 719 HOH A O 1 HETATM 7661 O O . HOH V 8 . ? -0.159 72.073 -88.285 1.00 40.15 ? 720 HOH A O 1 HETATM 7662 O O . HOH V 8 . ? -18.462 56.129 -111.618 1.00 49.96 ? 721 HOH A O 1 HETATM 7663 O O . HOH V 8 . ? 3.216 70.949 -108.895 1.00 52.86 ? 722 HOH A O 1 HETATM 7664 O O . HOH V 8 . ? -22.620 55.187 -71.976 1.00 43.52 ? 723 HOH A O 1 HETATM 7665 O O . HOH V 8 . ? 3.530 58.932 -62.422 1.00 43.45 ? 724 HOH A O 1 HETATM 7666 O O . HOH V 8 . ? -7.459 61.237 8.505 1.00 48.21 ? 725 HOH A O 1 HETATM 7667 O O . HOH V 8 . ? -14.161 77.933 -86.999 1.00 37.31 ? 726 HOH A O 1 HETATM 7668 O O . HOH V 8 . ? -4.949 56.243 -110.620 1.00 43.38 ? 727 HOH A O 1 HETATM 7669 O O . HOH V 8 . ? -12.573 60.936 -112.944 1.00 45.76 ? 728 HOH A O 1 HETATM 7670 O O . HOH V 8 . ? -7.876 45.074 -86.499 1.00 49.06 ? 729 HOH A O 1 HETATM 7671 O O . HOH V 8 . ? 8.101 67.017 -56.085 1.00 58.64 ? 730 HOH A O 1 HETATM 7672 O O . HOH V 8 . ? -27.303 62.049 -82.432 1.00 42.08 ? 731 HOH A O 1 HETATM 7673 O O . HOH V 8 . ? 0.227 54.632 -28.900 1.00 39.72 ? 732 HOH A O 1 HETATM 7674 O O . HOH V 8 . ? -8.780 67.167 -54.405 1.00 53.09 ? 733 HOH A O 1 HETATM 7675 O O . HOH V 8 . ? -11.411 73.954 -109.288 1.00 46.94 ? 734 HOH A O 1 HETATM 7676 O O . HOH V 8 . ? 10.186 71.174 -38.395 1.00 44.68 ? 735 HOH A O 1 HETATM 7677 O O . HOH V 8 . ? -17.275 64.914 -110.488 1.00 45.61 ? 736 HOH A O 1 HETATM 7678 O O . HOH V 8 . ? -0.854 55.698 -107.060 1.00 60.50 ? 737 HOH A O 1 HETATM 7679 O O . HOH V 8 . ? 4.607 61.689 -100.989 1.00 43.23 ? 738 HOH A O 1 HETATM 7680 O O . HOH V 8 . ? -25.559 58.282 -76.735 1.00 45.31 ? 739 HOH A O 1 HETATM 7681 O O . HOH V 8 . ? 5.838 55.993 -20.643 1.00 43.79 ? 740 HOH A O 1 HETATM 7682 O O . HOH V 8 . ? -0.970 44.468 -88.142 1.00 46.71 ? 741 HOH A O 1 HETATM 7683 O O . HOH V 8 . ? -11.865 46.702 -82.289 1.00 46.80 ? 742 HOH A O 1 HETATM 7684 O O . HOH V 8 . ? -29.485 64.406 -82.448 1.00 46.39 ? 743 HOH A O 1 HETATM 7685 O O . HOH V 8 . ? -20.356 78.934 -84.011 1.00 51.29 ? 744 HOH A O 1 HETATM 7686 O O . HOH V 8 . ? -9.613 81.502 -103.318 1.00 42.42 ? 745 HOH A O 1 HETATM 7687 O O . HOH V 8 . ? 3.737 53.177 -76.789 1.00 36.01 ? 746 HOH A O 1 HETATM 7688 O O . HOH V 8 . ? -18.563 52.952 -57.771 1.00 47.24 ? 747 HOH A O 1 HETATM 7689 O O . HOH V 8 . ? -19.847 74.237 -79.441 1.00 46.15 ? 748 HOH A O 1 HETATM 7690 O O . HOH V 8 . ? 1.126 46.283 -89.033 1.00 39.61 ? 749 HOH A O 1 HETATM 7691 O O . HOH V 8 . ? 0.037 74.563 -91.870 1.00 54.57 ? 750 HOH A O 1 HETATM 7692 O O . HOH V 8 . ? -4.355 45.256 -67.502 1.00 51.66 ? 751 HOH A O 1 HETATM 7693 O O . HOH V 8 . ? 7.352 61.045 -16.054 1.00 47.60 ? 752 HOH A O 1 HETATM 7694 O O . HOH V 8 . ? -1.831 47.118 -82.242 1.00 45.98 ? 753 HOH A O 1 HETATM 7695 O O . HOH V 8 . ? 16.858 64.831 -95.433 1.00 40.80 ? 754 HOH A O 1 HETATM 7696 O O . HOH V 8 . ? -0.335 73.787 -79.569 1.00 36.72 ? 755 HOH A O 1 HETATM 7697 O O . HOH V 8 . ? 3.294 49.353 -68.204 1.00 53.48 ? 756 HOH A O 1 HETATM 7698 O O . HOH V 8 . ? 8.234 65.043 -38.389 1.00 41.93 ? 757 HOH A O 1 HETATM 7699 O O . HOH V 8 . ? -7.397 44.375 -68.829 1.00 57.92 ? 758 HOH A O 1 HETATM 7700 O O . HOH V 8 . ? -10.374 53.633 -86.392 1.00 37.99 ? 759 HOH A O 1 HETATM 7701 O O . HOH V 8 . ? -4.380 46.959 -85.003 1.00 47.43 ? 760 HOH A O 1 HETATM 7702 O O . HOH V 8 . ? -0.206 71.860 -105.873 1.00 45.00 ? 761 HOH A O 1 HETATM 7703 O O . HOH V 8 . ? 3.477 60.334 -34.732 1.00 45.07 ? 762 HOH A O 1 HETATM 7704 O O . HOH V 8 . ? -25.162 70.779 -96.827 1.00 50.93 ? 763 HOH A O 1 HETATM 7705 O O . HOH V 8 . ? -5.443 47.806 -100.264 1.00 51.24 ? 764 HOH A O 1 HETATM 7706 O O . HOH V 8 . ? -25.610 68.175 -97.455 1.00 52.82 ? 765 HOH A O 1 HETATM 7707 O O . HOH V 8 . ? 4.550 49.489 -74.562 1.00 47.86 ? 766 HOH A O 1 HETATM 7708 O O . HOH V 8 . ? -20.999 71.300 -101.835 1.00 45.06 ? 767 HOH A O 1 HETATM 7709 O O . HOH V 8 . ? -23.440 57.995 -74.663 1.00 46.58 ? 768 HOH A O 1 HETATM 7710 O O . HOH V 8 . ? -6.692 47.778 -55.198 1.00 56.01 ? 769 HOH A O 1 HETATM 7711 O O . HOH V 8 . ? -19.001 49.219 -63.104 1.00 56.66 ? 770 HOH A O 1 HETATM 7712 O O . HOH V 8 . ? -5.671 71.925 -70.884 1.00 46.86 ? 771 HOH A O 1 HETATM 7713 O O . HOH V 8 . ? -8.472 76.273 -88.132 1.00 57.24 ? 772 HOH A O 1 HETATM 7714 O O . HOH V 8 . ? 3.240 68.625 -110.769 1.00 47.97 ? 773 HOH A O 1 HETATM 7715 O O . HOH V 8 . ? 8.295 54.288 -77.029 1.00 52.26 ? 774 HOH A O 1 HETATM 7716 O O . HOH V 8 . ? -3.959 42.437 -86.029 1.00 50.41 ? 775 HOH A O 1 HETATM 7717 O O . HOH V 8 . ? -10.935 62.104 -49.801 1.00 51.91 ? 776 HOH A O 1 HETATM 7718 O O . HOH V 8 . ? -29.872 70.188 -89.755 1.00 40.89 ? 777 HOH A O 1 HETATM 7719 O O . HOH V 8 . ? -1.997 75.578 -96.269 1.00 45.26 ? 778 HOH A O 1 HETATM 7720 O O . HOH V 8 . ? 9.193 56.839 -86.585 1.00 53.64 ? 779 HOH A O 1 HETATM 7721 O O . HOH V 8 . ? 2.666 64.643 -66.142 1.00 50.07 ? 780 HOH A O 1 HETATM 7722 O O . HOH V 8 . ? 9.610 69.489 -107.372 1.00 50.34 ? 781 HOH A O 1 HETATM 7723 O O . HOH V 8 . ? -32.307 68.705 -89.784 1.00 48.45 ? 782 HOH A O 1 HETATM 7724 O O . HOH V 8 . ? -8.592 58.383 -33.360 1.00 46.19 ? 783 HOH A O 1 HETATM 7725 O O . HOH V 8 . ? 6.332 54.096 -99.936 1.00 52.26 ? 784 HOH A O 1 HETATM 7726 O O . HOH V 8 . ? -0.061 45.946 -73.545 1.00 47.22 ? 785 HOH A O 1 HETATM 7727 O O . HOH V 8 . ? 1.028 76.179 -97.856 1.00 50.06 ? 786 HOH A O 1 HETATM 7728 O O . HOH V 8 . ? 1.317 73.209 -104.638 1.00 52.42 ? 787 HOH A O 1 HETATM 7729 O O . HOH V 8 . ? -3.215 45.736 -79.018 1.00 56.31 ? 788 HOH A O 1 HETATM 7730 O O . HOH V 8 . ? 2.597 58.480 -39.084 1.00 55.43 ? 789 HOH A O 1 HETATM 7731 O O . HOH V 8 . ? 4.526 58.887 -37.397 1.00 47.81 ? 790 HOH A O 1 HETATM 7732 O O . HOH V 8 . ? -11.697 46.991 -78.460 1.00 53.41 ? 791 HOH A O 1 HETATM 7733 O O . HOH V 8 . ? 10.488 65.379 -99.608 1.00 40.71 ? 792 HOH A O 1 HETATM 7734 O O . HOH V 8 . ? -7.398 46.708 -93.118 1.00 38.83 ? 793 HOH A O 1 HETATM 7735 O O . HOH V 8 . ? 2.921 75.338 -102.456 1.00 40.50 ? 794 HOH A O 1 HETATM 7736 O O . HOH V 8 . ? -1.036 56.736 -39.922 1.00 48.50 ? 795 HOH A O 1 HETATM 7737 O O . HOH V 8 . ? -19.224 62.522 -109.492 1.00 55.87 ? 796 HOH A O 1 HETATM 7738 O O . HOH V 8 . ? 2.277 72.907 -90.436 1.00 53.90 ? 797 HOH A O 1 HETATM 7739 O O . HOH V 8 . ? 5.545 59.423 -61.280 1.00 53.37 ? 798 HOH A O 1 HETATM 7740 O O . HOH V 8 . ? 0.169 47.717 -78.615 1.00 51.27 ? 799 HOH A O 1 HETATM 7741 O O . HOH V 8 . ? 6.067 56.370 -83.280 1.00 53.65 ? 800 HOH A O 1 HETATM 7742 O O . HOH V 8 . ? -16.887 47.715 -58.679 1.00 62.81 ? 801 HOH A O 1 HETATM 7743 O O . HOH V 8 . ? 4.324 45.249 -92.200 1.00 59.15 ? 802 HOH A O 1 HETATM 7744 O O . HOH V 8 . ? -13.173 48.815 -81.154 1.00 41.94 ? 803 HOH A O 1 HETATM 7745 O O . HOH V 8 . ? 7.634 73.303 -24.045 1.00 47.18 ? 804 HOH A O 1 HETATM 7746 O O . HOH V 8 . ? 5.439 48.540 -94.215 1.00 47.78 ? 805 HOH A O 1 HETATM 7747 O O . HOH V 8 . ? 3.851 53.038 -100.047 1.00 47.07 ? 806 HOH A O 1 HETATM 7748 O O . HOH V 8 . ? -26.672 63.281 -76.746 1.00 54.37 ? 807 HOH A O 1 HETATM 7749 O O . HOH V 8 . ? -11.219 62.932 -71.501 1.00 40.67 ? 808 HOH A O 1 HETATM 7750 O O . HOH V 8 . ? -16.782 48.550 -56.502 1.00 61.97 ? 809 HOH A O 1 HETATM 7751 O O . HOH V 8 . ? -1.574 56.348 -37.534 1.00 57.73 ? 810 HOH A O 1 HETATM 7752 O O . HOH V 8 . ? 5.849 72.024 -107.948 1.00 49.34 ? 811 HOH A O 1 HETATM 7753 O O . HOH V 8 . ? 4.173 57.903 -53.331 1.00 42.46 ? 812 HOH A O 1 HETATM 7754 O O . HOH V 8 . ? 3.875 54.554 -49.192 1.00 50.89 ? 813 HOH A O 1 HETATM 7755 O O . HOH V 8 . ? 6.154 51.685 -73.732 1.00 50.32 ? 814 HOH A O 1 HETATM 7756 O O . HOH V 8 . ? 4.971 63.743 -85.734 1.00 50.21 ? 815 HOH A O 1 HETATM 7757 O O . HOH V 8 . ? -2.464 65.165 -67.112 1.00 46.71 ? 816 HOH A O 1 HETATM 7758 O O . HOH V 8 . ? -29.824 63.036 -87.816 1.00 54.96 ? 817 HOH A O 1 HETATM 7759 O O . HOH V 8 . ? -4.929 76.722 -87.619 1.00 57.47 ? 818 HOH A O 1 HETATM 7760 O O . HOH V 8 . ? -12.520 77.796 -105.736 1.00 53.16 ? 819 HOH A O 1 HETATM 7761 O O . HOH V 8 . ? -29.360 62.380 -84.016 1.00 43.86 ? 820 HOH A O 1 HETATM 7762 O O . HOH V 8 . ? -9.043 46.690 -55.177 1.00 58.44 ? 821 HOH A O 1 HETATM 7763 O O . HOH V 8 . ? 0.889 50.119 -22.480 1.00 54.22 ? 822 HOH A O 1 HETATM 7764 O O . HOH V 8 . ? -0.024 58.484 -113.843 1.00 59.81 ? 823 HOH A O 1 HETATM 7765 O O . HOH V 8 . ? 5.676 51.584 -25.244 1.00 51.70 ? 824 HOH A O 1 HETATM 7766 O O . HOH V 8 . ? -18.004 62.399 -106.200 1.00 52.78 ? 825 HOH A O 1 HETATM 7767 O O . HOH V 8 . ? -12.952 51.881 -90.280 1.00 36.41 ? 826 HOH A O 1 HETATM 7768 O O . HOH V 8 . ? -17.801 75.314 -80.885 1.00 46.24 ? 827 HOH A O 1 HETATM 7769 O O . HOH V 8 . ? 7.578 59.284 -86.334 1.00 48.79 ? 828 HOH A O 1 HETATM 7770 O O . HOH V 8 . ? -12.017 49.416 -90.066 1.00 34.79 ? 829 HOH A O 1 HETATM 7771 O O . HOH V 8 . ? 8.116 71.894 -107.358 1.00 50.11 ? 830 HOH A O 1 HETATM 7772 O O . HOH V 8 . ? 3.520 46.667 -87.593 1.00 45.84 ? 831 HOH A O 1 HETATM 7773 O O . HOH V 8 . ? 12.206 64.160 -101.298 1.00 42.20 ? 832 HOH A O 1 HETATM 7774 O O . HOH V 8 . ? 8.741 66.759 -53.475 1.00 60.29 ? 833 HOH A O 1 HETATM 7775 O O . HOH V 8 . ? -7.720 49.776 -99.921 1.00 46.42 ? 834 HOH A O 1 HETATM 7776 O O . HOH V 8 . ? 4.535 62.891 -70.139 1.00 52.28 ? 835 HOH A O 1 HETATM 7777 O O . HOH V 8 . ? 5.226 45.955 -89.828 1.00 55.91 ? 836 HOH A O 1 HETATM 7778 O O . HOH V 8 . ? 6.817 60.684 -59.159 1.00 56.41 ? 837 HOH A O 1 HETATM 7779 O O . HOH V 8 . ? -32.967 67.202 -91.949 1.00 53.69 ? 838 HOH A O 1 HETATM 7780 O O . HOH V 8 . ? 3.753 44.949 -85.287 1.00 51.72 ? 839 HOH A O 1 HETATM 7781 O O . HOH V 8 . ? -12.677 50.531 -96.200 1.00 50.72 ? 840 HOH A O 1 HETATM 7782 O O . HOH V 8 . ? 6.581 47.590 -90.858 1.00 59.19 ? 841 HOH A O 1 HETATM 7783 O O . HOH V 8 . ? 3.841 49.362 -87.049 1.00 43.67 ? 842 HOH A O 1 HETATM 7784 O O . HOH V 8 . ? 8.045 48.732 -95.091 1.00 49.31 ? 843 HOH A O 1 HETATM 7785 O O . HOH V 8 . ? 2.670 51.778 -88.165 1.00 39.27 ? 844 HOH A O 1 HETATM 7786 O O . HOH V 8 . ? -10.635 53.842 -95.647 1.00 41.48 ? 845 HOH A O 1 HETATM 7787 O O . HOH V 8 . ? 8.815 65.993 -23.555 1.00 51.29 ? 846 HOH A O 1 HETATM 7788 O O . HOH V 8 . ? 1.566 54.902 -44.505 1.00 40.20 ? 847 HOH A O 1 HETATM 7789 O O . HOH V 8 . ? -0.525 64.965 -29.139 1.00 34.70 ? 848 HOH A O 1 HETATM 7790 O O . HOH V 8 . ? -24.181 54.552 -97.885 1.00 47.82 ? 849 HOH A O 1 HETATM 7791 O O . HOH V 8 . ? 1.302 65.184 -77.496 1.00 42.50 ? 850 HOH A O 1 HETATM 7792 O O . HOH V 8 . ? 7.421 53.105 -95.518 1.00 48.70 ? 851 HOH A O 1 HETATM 7793 O O . HOH V 8 . ? -20.096 51.435 -71.071 1.00 44.36 ? 852 HOH A O 1 HETATM 7794 O O . HOH V 8 . ? -2.694 49.800 -103.950 1.00 49.08 ? 853 HOH A O 1 HETATM 7795 O O . HOH V 8 . ? 11.066 65.567 -36.466 1.00 45.57 ? 854 HOH A O 1 HETATM 7796 O O . HOH V 8 . ? -17.007 60.470 -60.905 1.00 44.08 ? 855 HOH A O 1 HETATM 7797 O O . HOH V 8 . ? -16.706 59.500 -65.108 1.00 43.62 ? 856 HOH A O 1 HETATM 7798 O O . HOH V 8 . ? 4.406 71.889 -91.186 1.00 54.52 ? 857 HOH A O 1 HETATM 7799 O O . HOH V 8 . ? 1.944 75.118 -108.664 1.00 49.83 ? 858 HOH A O 1 HETATM 7800 O O . HOH V 8 . ? -29.927 75.830 -96.446 1.00 51.29 ? 859 HOH A O 1 HETATM 7801 O O . HOH V 8 . ? 5.065 61.557 -68.369 1.00 51.34 ? 860 HOH A O 1 HETATM 7802 O O . HOH V 8 . ? -24.035 73.863 -97.596 1.00 51.53 ? 861 HOH A O 1 HETATM 7803 O O . HOH V 8 . ? 4.790 49.730 -61.649 1.00 54.95 ? 862 HOH A O 1 HETATM 7804 O O . HOH V 8 . ? 2.440 77.125 -100.137 1.00 43.34 ? 863 HOH A O 1 HETATM 7805 O O . HOH V 8 . ? -29.471 69.644 -86.106 1.00 46.05 ? 864 HOH A O 1 HETATM 7806 O O . HOH V 8 . ? -5.168 49.268 -102.451 1.00 50.67 ? 865 HOH A O 1 HETATM 7807 O O . HOH V 8 . ? -24.645 57.268 -88.219 1.00 49.14 ? 866 HOH A O 1 HETATM 7808 O O . HOH V 8 . ? 7.011 58.996 -56.406 1.00 50.37 ? 867 HOH A O 1 HETATM 7809 O O . HOH V 8 . ? 11.164 72.947 -39.421 1.00 43.53 ? 868 HOH A O 1 HETATM 7810 O O . HOH V 8 . ? -2.222 44.709 -85.997 1.00 52.10 ? 869 HOH A O 1 HETATM 7811 O O . HOH V 8 . ? -23.984 64.901 -97.002 1.00 48.11 ? 870 HOH A O 1 HETATM 7812 O O . HOH V 8 . ? -28.771 60.083 -84.758 1.00 47.49 ? 871 HOH A O 1 HETATM 7813 O O . HOH V 8 . ? -21.095 83.175 -86.426 1.00 51.86 ? 872 HOH A O 1 HETATM 7814 O O . HOH V 8 . ? -30.108 63.453 -79.766 1.00 52.73 ? 873 HOH A O 1 HETATM 7815 O O . HOH V 8 . ? -19.963 49.937 -102.593 1.00 50.65 ? 874 HOH A O 1 HETATM 7816 O O . HOH V 8 . ? 8.789 61.396 -107.978 1.00 54.50 ? 875 HOH A O 1 HETATM 7817 O O . HOH V 8 . ? -16.484 48.650 -68.297 1.00 57.67 ? 876 HOH A O 1 HETATM 7818 O O . HOH V 8 . ? 4.664 58.311 -65.710 1.00 54.83 ? 877 HOH A O 1 HETATM 7819 O O . HOH V 8 . ? -28.868 66.488 -94.428 1.00 45.11 ? 878 HOH A O 1 HETATM 7820 O O . HOH V 8 . ? -11.352 50.079 -100.022 1.00 51.07 ? 879 HOH A O 1 HETATM 7821 O O . HOH V 8 . ? -9.850 67.652 -50.343 1.00 51.65 ? 880 HOH A O 1 HETATM 7822 O O . HOH V 8 . ? -32.454 67.229 -87.666 1.00 46.93 ? 881 HOH A O 1 HETATM 7823 O O . HOH V 8 . ? 5.517 64.622 -58.826 1.00 50.47 ? 882 HOH A O 1 HETATM 7824 O O . HOH V 8 . ? -13.203 46.233 -62.569 1.00 54.39 ? 883 HOH A O 1 HETATM 7825 O O . HOH V 8 . ? -9.220 56.116 -32.363 1.00 53.35 ? 884 HOH A O 1 HETATM 7826 O O . HOH V 8 . ? -31.850 65.232 -78.855 1.00 52.21 ? 885 HOH A O 1 HETATM 7827 O O . HOH V 8 . ? -27.078 60.608 -77.875 1.00 54.09 ? 886 HOH A O 1 HETATM 7828 O O . HOH V 8 . ? -5.122 48.150 -70.179 1.00 54.27 ? 887 HOH A O 1 HETATM 7829 O O . HOH V 8 . ? -11.594 47.981 -72.719 1.00 51.44 ? 888 HOH A O 1 HETATM 7830 O O . HOH V 8 . ? 12.725 59.781 -27.952 1.00 60.80 ? 889 HOH A O 1 HETATM 7831 O O . HOH V 8 . ? 2.451 63.824 -80.257 1.00 51.54 ? 890 HOH A O 1 HETATM 7832 O O . HOH V 8 . ? -1.906 50.283 -50.072 1.00 54.76 ? 891 HOH A O 1 HETATM 7833 O O . HOH V 8 . ? 6.301 52.767 -62.659 1.00 54.78 ? 892 HOH A O 1 HETATM 7834 O O . HOH V 8 . ? -8.901 42.528 -90.022 1.00 47.22 ? 893 HOH A O 1 HETATM 7835 O O . HOH V 8 . ? -28.613 74.124 -97.280 1.00 51.60 ? 894 HOH A O 1 HETATM 7836 O O . HOH V 8 . ? 10.366 71.153 -53.867 1.00 58.79 ? 895 HOH A O 1 HETATM 7837 O O . HOH V 8 . ? 10.406 54.416 -98.920 1.00 54.95 ? 896 HOH A O 1 HETATM 7838 O O . HOH V 8 . ? 6.308 59.906 -108.944 1.00 48.93 ? 897 HOH A O 1 HETATM 7839 O O . HOH V 8 . ? -10.006 50.888 -53.411 1.00 57.57 ? 898 HOH A O 1 HETATM 7840 O O . HOH V 8 . ? 13.194 60.140 -32.391 1.00 54.21 ? 899 HOH A O 1 HETATM 7841 O O . HOH V 8 . ? 0.434 50.470 -49.946 1.00 51.02 ? 900 HOH A O 1 HETATM 7842 O O . HOH V 8 . ? -5.025 54.810 -20.778 1.00 45.93 ? 901 HOH A O 1 HETATM 7843 O O . HOH V 8 . ? -3.855 56.147 -39.794 1.00 58.74 ? 902 HOH A O 1 HETATM 7844 O O . HOH V 8 . ? -25.536 63.787 -95.185 1.00 50.47 ? 903 HOH A O 1 HETATM 7845 O O . HOH V 8 . ? 9.937 55.783 -75.023 1.00 53.23 ? 904 HOH A O 1 HETATM 7846 O O . HOH V 8 . ? -12.749 60.855 8.336 1.00 52.09 ? 905 HOH A O 1 HETATM 7847 O O . HOH V 8 . ? -23.840 61.706 -94.672 1.00 47.82 ? 906 HOH A O 1 HETATM 7848 O O . HOH V 8 . ? -5.845 45.702 -81.728 1.00 48.47 ? 907 HOH A O 1 HETATM 7849 O O . HOH V 8 . ? 2.819 48.844 -57.659 1.00 51.34 ? 908 HOH A O 1 HETATM 7850 O O . HOH V 8 . ? 2.868 77.022 -104.478 1.00 52.55 ? 909 HOH A O 1 HETATM 7851 O O . HOH V 8 . ? 4.658 60.575 -84.714 1.00 52.31 ? 910 HOH A O 1 HETATM 7852 O O . HOH V 8 . ? -14.010 46.757 -60.536 1.00 56.40 ? 911 HOH A O 1 HETATM 7853 O O . HOH V 8 . ? -25.252 75.200 -80.851 1.00 53.00 ? 912 HOH A O 1 HETATM 7854 O O . HOH V 8 . ? 1.413 48.273 -81.375 1.00 47.99 ? 913 HOH A O 1 HETATM 7855 O O . HOH V 8 . ? 9.397 57.077 -26.295 1.00 54.26 ? 914 HOH A O 1 HETATM 7856 O O . HOH V 8 . ? 14.313 62.179 -31.126 1.00 53.34 ? 915 HOH A O 1 HETATM 7857 O O . HOH V 8 . ? 7.712 61.274 -68.770 1.00 53.45 ? 916 HOH A O 1 HETATM 7858 O O . HOH V 8 . ? -17.823 50.447 -102.973 1.00 52.27 ? 917 HOH A O 1 HETATM 7859 O O . HOH V 8 . ? 5.688 56.948 -85.767 1.00 56.51 ? 918 HOH A O 1 HETATM 7860 O O . HOH V 8 . ? -7.098 45.331 -99.465 1.00 57.83 ? 919 HOH A O 1 HETATM 7861 O O . HOH V 8 . ? -9.433 78.266 -87.040 1.00 49.28 ? 920 HOH A O 1 HETATM 7862 O O . HOH V 8 . ? 3.360 50.429 -55.367 1.00 63.46 ? 921 HOH A O 1 HETATM 7863 O O . HOH V 8 . ? 9.173 51.434 -77.471 1.00 60.73 ? 922 HOH A O 1 HETATM 7864 O O . HOH V 8 . ? -5.839 57.478 -38.410 1.00 51.84 ? 923 HOH A O 1 HETATM 7865 O O . HOH V 8 . ? -2.921 47.965 -52.475 1.00 53.53 ? 924 HOH A O 1 HETATM 7866 O O . HOH V 8 . ? 2.858 54.278 -29.469 1.00 30.75 ? 925 HOH A O 1 HETATM 7867 O O . HOH V 8 . ? -9.595 51.319 -93.389 1.00 34.84 ? 926 HOH A O 1 HETATM 7868 O O . HOH V 8 . ? 3.317 66.423 -62.515 1.00 51.88 ? 927 HOH A O 1 HETATM 7869 O O . HOH V 8 . ? -24.580 77.870 -84.764 1.00 58.19 ? 928 HOH A O 1 HETATM 7870 O O . HOH V 8 . ? -10.573 55.198 -84.415 1.00 37.13 ? 929 HOH A O 1 HETATM 7871 O O . HOH V 8 . ? 16.113 67.821 -104.633 1.00 52.63 ? 930 HOH A O 1 HETATM 7872 O O . HOH V 8 . ? -23.187 73.614 -79.849 1.00 41.11 ? 931 HOH A O 1 HETATM 7873 O O . HOH V 8 . ? 16.732 64.269 -100.561 1.00 56.72 ? 932 HOH A O 1 HETATM 7874 O O . HOH V 8 . ? -26.092 60.609 -86.445 1.00 48.81 ? 933 HOH A O 1 HETATM 7875 O O . HOH V 8 . ? -22.393 67.486 -101.519 1.00 46.98 ? 934 HOH A O 1 HETATM 7876 O O . HOH V 8 . ? -4.649 77.314 -91.139 1.00 54.78 ? 935 HOH A O 1 HETATM 7877 O O . HOH V 8 . ? 6.412 65.982 -89.008 1.00 48.16 ? 936 HOH A O 1 HETATM 7878 O O . HOH V 8 . ? 14.481 63.370 -99.102 1.00 51.07 ? 937 HOH A O 1 HETATM 7879 O O . HOH V 8 . ? 0.281 62.809 -90.421 1.00 39.37 ? 938 HOH A O 1 HETATM 7880 O O . HOH V 8 . ? 8.013 55.721 -19.530 1.00 54.95 ? 939 HOH A O 1 HETATM 7881 O O . HOH V 8 . ? -20.318 75.209 -107.317 1.00 54.60 ? 940 HOH A O 1 HETATM 7882 O O . HOH V 8 . ? -15.472 58.014 -113.420 1.00 47.60 ? 941 HOH A O 1 HETATM 7883 O O . HOH V 8 . ? -8.758 78.713 -90.918 1.00 52.10 ? 942 HOH A O 1 HETATM 7884 O O . HOH V 8 . ? -21.450 59.851 -105.174 1.00 52.24 ? 943 HOH A O 1 HETATM 7885 O O . HOH V 8 . ? -13.494 53.916 -108.163 1.00 53.76 ? 944 HOH A O 1 HETATM 7886 O O . HOH V 8 . ? 1.722 69.166 -115.135 1.00 53.01 ? 945 HOH A O 1 HETATM 7887 O O . HOH V 8 . ? -24.783 55.411 -73.635 1.00 53.12 ? 946 HOH A O 1 HETATM 7888 O O . HOH V 8 . ? -24.251 58.168 -69.595 1.00 62.91 ? 947 HOH A O 1 HETATM 7889 O O . HOH V 8 . ? -2.287 47.019 -55.321 1.00 55.93 ? 948 HOH A O 1 HETATM 7890 O O . HOH V 8 . ? -2.267 56.449 -32.848 1.00 57.14 ? 949 HOH A O 1 HETATM 7891 O O . HOH V 8 . ? 6.822 62.999 -55.784 1.00 58.77 ? 950 HOH A O 1 HETATM 7892 O O . HOH V 8 . ? 3.472 51.471 -27.082 1.00 56.49 ? 951 HOH A O 1 HETATM 7893 O O . HOH V 8 . ? 3.548 65.959 -85.608 1.00 47.44 ? 952 HOH A O 1 HETATM 7894 O O . HOH V 8 . ? 3.545 47.356 -96.847 1.00 56.98 ? 953 HOH A O 1 HETATM 7895 O O . HOH V 8 . ? -22.154 79.386 -85.632 1.00 60.64 ? 954 HOH A O 1 HETATM 7896 O O . HOH V 8 . ? 4.617 66.771 -83.420 1.00 62.81 ? 955 HOH A O 1 HETATM 7897 O O . HOH V 8 . ? -2.967 66.224 -69.960 1.00 46.86 ? 956 HOH A O 1 HETATM 7898 O O . HOH V 8 . ? -7.809 80.174 -92.518 1.00 57.61 ? 957 HOH A O 1 HETATM 7899 O O . HOH V 8 . ? 1.170 48.271 -74.190 1.00 59.52 ? 958 HOH A O 1 HETATM 7900 O O . HOH V 8 . ? -7.055 76.932 -90.745 1.00 52.87 ? 959 HOH A O 1 HETATM 7901 O O . HOH V 8 . ? -16.510 69.475 -66.396 1.00 56.43 ? 960 HOH A O 1 HETATM 7902 O O . HOH V 8 . ? 6.544 49.656 -87.740 1.00 62.69 ? 961 HOH A O 1 HETATM 7903 O O . HOH V 8 . ? -15.135 62.315 -59.906 1.00 56.87 ? 962 HOH A O 1 HETATM 7904 O O . HOH V 8 . ? -10.795 44.764 -80.685 1.00 62.43 ? 963 HOH A O 1 HETATM 7905 O O . HOH V 8 . ? -2.417 45.612 -69.789 1.00 63.71 ? 964 HOH A O 1 HETATM 7906 O O . HOH V 8 . ? 4.484 53.172 -57.222 1.00 57.92 ? 965 HOH A O 1 HETATM 7907 O O . HOH V 8 . ? -3.755 44.011 -81.783 1.00 61.59 ? 966 HOH A O 1 HETATM 7908 O O . HOH V 8 . ? -14.641 62.945 -62.389 1.00 54.38 ? 967 HOH A O 1 HETATM 7909 O O . HOH V 8 . ? -2.038 76.085 -93.045 1.00 59.73 ? 968 HOH A O 1 HETATM 7910 O O . HOH V 8 . ? -0.114 70.266 -115.992 1.00 61.76 ? 969 HOH A O 1 HETATM 7911 O O . HOH V 8 . ? 7.384 61.949 -50.991 1.00 52.60 ? 970 HOH A O 1 HETATM 7912 O O . HOH V 8 . ? 2.044 76.497 -92.177 1.00 57.90 ? 971 HOH A O 1 HETATM 7913 O O . HOH V 8 . ? -25.262 70.610 -78.405 1.00 57.59 ? 972 HOH A O 1 HETATM 7914 O O . HOH V 8 . ? -5.398 54.655 -31.212 1.00 71.87 ? 973 HOH A O 1 HETATM 7915 O O . HOH V 8 . ? 11.499 68.107 -109.291 1.00 54.90 ? 974 HOH A O 1 HETATM 7916 O O . HOH W 8 . ? -9.726 61.535 -6.336 1.00 27.23 ? 301 HOH B O 1 HETATM 7917 O O . HOH W 8 . ? -2.454 70.155 -32.483 1.00 19.66 ? 302 HOH B O 1 HETATM 7918 O O . HOH W 8 . ? 0.095 63.514 -12.754 1.00 21.55 ? 303 HOH B O 1 HETATM 7919 O O . HOH W 8 . ? 1.290 71.446 -4.166 1.00 20.13 ? 304 HOH B O 1 HETATM 7920 O O . HOH W 8 . ? 9.137 74.831 -71.120 1.00 24.00 ? 305 HOH B O 1 HETATM 7921 O O . HOH W 8 . ? -6.891 76.464 -20.734 1.00 22.92 ? 306 HOH B O 1 HETATM 7922 O O . HOH W 8 . ? 5.242 80.576 -78.734 1.00 23.79 ? 307 HOH B O 1 HETATM 7923 O O . HOH W 8 . ? 3.711 72.695 -67.805 1.00 28.25 ? 308 HOH B O 1 HETATM 7924 O O . HOH W 8 . ? -13.876 81.665 -40.582 1.00 27.24 ? 309 HOH B O 1 HETATM 7925 O O . HOH W 8 . ? -16.038 75.934 -3.310 1.00 31.51 ? 310 HOH B O 1 HETATM 7926 O O . HOH W 8 . ? 4.825 66.070 -8.461 1.00 25.10 ? 311 HOH B O 1 HETATM 7927 O O . HOH W 8 . ? -13.995 67.026 9.152 1.00 31.39 ? 312 HOH B O 1 HETATM 7928 O O . HOH W 8 . ? 5.169 79.960 -75.417 1.00 19.05 ? 313 HOH B O 1 HETATM 7929 O O . HOH W 8 . ? 2.914 80.854 -77.015 1.00 26.92 ? 314 HOH B O 1 HETATM 7930 O O . HOH W 8 . ? 2.149 56.661 -13.318 1.00 33.79 ? 315 HOH B O 1 HETATM 7931 O O . HOH W 8 . ? -16.163 77.592 0.213 1.00 30.17 ? 316 HOH B O 1 HETATM 7932 O O . HOH W 8 . ? -4.209 67.696 -72.276 1.00 41.36 ? 317 HOH B O 1 HETATM 7933 O O . HOH W 8 . ? -6.729 65.471 7.479 1.00 33.57 ? 318 HOH B O 1 HETATM 7934 O O . HOH W 8 . ? 5.400 79.424 -54.406 1.00 27.71 ? 319 HOH B O 1 HETATM 7935 O O . HOH W 8 . ? -8.668 69.987 14.394 1.00 29.03 ? 320 HOH B O 1 HETATM 7936 O O . HOH W 8 . ? 0.528 79.300 -78.000 1.00 28.46 ? 321 HOH B O 1 HETATM 7937 O O . HOH W 8 . ? -0.613 56.359 -11.837 1.00 28.77 ? 322 HOH B O 1 HETATM 7938 O O . HOH W 8 . ? 3.477 69.855 -72.558 1.00 32.55 ? 323 HOH B O 1 HETATM 7939 O O . HOH W 8 . ? -11.436 57.150 -0.141 1.00 30.41 ? 324 HOH B O 1 HETATM 7940 O O . HOH W 8 . ? 5.060 73.027 -17.767 1.00 22.80 ? 325 HOH B O 1 HETATM 7941 O O . HOH W 8 . ? -4.846 76.402 -0.715 1.00 25.36 ? 326 HOH B O 1 HETATM 7942 O O . HOH W 8 . ? -3.254 79.019 -16.437 1.00 23.31 ? 327 HOH B O 1 HETATM 7943 O O . HOH W 8 . ? -8.729 75.481 -18.201 1.00 27.79 ? 328 HOH B O 1 HETATM 7944 O O . HOH W 8 . ? 5.599 75.917 -12.019 1.00 35.95 ? 329 HOH B O 1 HETATM 7945 O O . HOH W 8 . ? 6.315 75.622 -24.234 1.00 32.59 ? 330 HOH B O 1 HETATM 7946 O O . HOH W 8 . ? -5.398 79.458 -12.912 1.00 25.28 ? 331 HOH B O 1 HETATM 7947 O O . HOH W 8 . ? -13.347 58.996 -12.520 1.00 30.67 ? 332 HOH B O 1 HETATM 7948 O O . HOH W 8 . ? 3.317 82.853 -42.512 1.00 31.24 ? 333 HOH B O 1 HETATM 7949 O O . HOH W 8 . ? 5.520 77.230 -26.240 1.00 24.47 ? 334 HOH B O 1 HETATM 7950 O O . HOH W 8 . ? 8.008 76.110 -21.973 1.00 28.75 ? 335 HOH B O 1 HETATM 7951 O O . HOH W 8 . ? -1.963 72.005 -53.877 1.00 42.84 ? 336 HOH B O 1 HETATM 7952 O O . HOH W 8 . ? -3.445 52.136 -16.006 1.00 40.18 ? 337 HOH B O 1 HETATM 7953 O O . HOH W 8 . ? -8.779 73.237 -16.268 1.00 24.24 ? 338 HOH B O 1 HETATM 7954 O O . HOH W 8 . ? -15.998 75.913 10.999 1.00 30.10 ? 339 HOH B O 1 HETATM 7955 O O . HOH W 8 . ? 11.828 75.050 -78.938 1.00 31.84 ? 340 HOH B O 1 HETATM 7956 O O . HOH W 8 . ? -3.433 55.781 -18.623 1.00 37.47 ? 341 HOH B O 1 HETATM 7957 O O . HOH W 8 . ? -13.474 78.524 -0.624 1.00 27.58 ? 342 HOH B O 1 HETATM 7958 O O . HOH W 8 . ? 7.162 72.749 -50.987 1.00 33.34 ? 343 HOH B O 1 HETATM 7959 O O . HOH W 8 . ? -12.560 66.447 -35.426 1.00 31.04 ? 344 HOH B O 1 HETATM 7960 O O . HOH W 8 . ? 5.592 69.684 -80.760 1.00 40.99 ? 345 HOH B O 1 HETATM 7961 O O . HOH W 8 . ? -0.276 76.597 6.091 1.00 36.88 ? 346 HOH B O 1 HETATM 7962 O O . HOH W 8 . ? 4.510 73.426 -26.851 1.00 24.92 ? 347 HOH B O 1 HETATM 7963 O O . HOH W 8 . ? -7.740 56.396 -21.518 1.00 36.17 ? 348 HOH B O 1 HETATM 7964 O O . HOH W 8 . ? -8.678 54.505 -8.374 1.00 35.99 ? 349 HOH B O 1 HETATM 7965 O O . HOH W 8 . ? -5.176 67.468 -59.230 1.00 33.94 ? 350 HOH B O 1 HETATM 7966 O O . HOH W 8 . ? 4.098 78.391 -81.371 1.00 40.06 ? 351 HOH B O 1 HETATM 7967 O O . HOH W 8 . ? -3.431 61.391 -2.706 1.00 31.43 ? 352 HOH B O 1 HETATM 7968 O O . HOH W 8 . ? 0.453 75.820 11.055 1.00 37.28 ? 353 HOH B O 1 HETATM 7969 O O . HOH W 8 . ? -10.275 73.539 -14.055 1.00 33.72 ? 354 HOH B O 1 HETATM 7970 O O . HOH W 8 . ? -9.136 67.438 12.939 1.00 32.96 ? 355 HOH B O 1 HETATM 7971 O O . HOH W 8 . ? -12.865 65.682 12.372 1.00 37.73 ? 356 HOH B O 1 HETATM 7972 O O . HOH W 8 . ? -11.832 77.548 -7.369 1.00 28.38 ? 357 HOH B O 1 HETATM 7973 O O . HOH W 8 . ? -9.436 77.852 8.608 1.00 32.23 ? 358 HOH B O 1 HETATM 7974 O O . HOH W 8 . ? 6.883 74.961 -49.408 1.00 31.96 ? 359 HOH B O 1 HETATM 7975 O O . HOH W 8 . ? -14.751 65.069 6.257 1.00 28.62 ? 360 HOH B O 1 HETATM 7976 O O . HOH W 8 . ? -16.980 70.837 -19.978 1.00 34.06 ? 361 HOH B O 1 HETATM 7977 O O . HOH W 8 . ? -8.208 82.067 8.186 1.00 32.35 ? 362 HOH B O 1 HETATM 7978 O O . HOH W 8 . ? -14.179 78.970 -3.308 1.00 36.91 ? 363 HOH B O 1 HETATM 7979 O O . HOH W 8 . ? -5.221 74.416 18.640 1.00 34.61 ? 364 HOH B O 1 HETATM 7980 O O . HOH W 8 . ? 3.974 57.944 -15.864 1.00 37.60 ? 365 HOH B O 1 HETATM 7981 O O . HOH W 8 . ? 7.641 69.732 -7.727 1.00 32.94 ? 366 HOH B O 1 HETATM 7982 O O . HOH W 8 . ? -2.351 77.021 3.120 1.00 38.17 ? 367 HOH B O 1 HETATM 7983 O O . HOH W 8 . ? 2.758 70.714 -69.464 1.00 36.17 ? 368 HOH B O 1 HETATM 7984 O O . HOH W 8 . ? -17.520 70.668 1.470 1.00 29.34 ? 369 HOH B O 1 HETATM 7985 O O . HOH W 8 . ? 4.952 68.929 -58.747 1.00 40.07 ? 370 HOH B O 1 HETATM 7986 O O . HOH W 8 . ? -17.340 66.208 6.475 1.00 39.40 ? 371 HOH B O 1 HETATM 7987 O O . HOH W 8 . ? -8.839 56.156 -14.148 1.00 37.25 ? 372 HOH B O 1 HETATM 7988 O O . HOH W 8 . ? -12.376 59.245 4.978 1.00 31.54 ? 373 HOH B O 1 HETATM 7989 O O . HOH W 8 . ? -15.830 70.210 -34.974 1.00 39.20 ? 374 HOH B O 1 HETATM 7990 O O . HOH W 8 . ? 0.266 80.288 -43.809 1.00 39.39 ? 375 HOH B O 1 HETATM 7991 O O . HOH W 8 . ? 5.678 79.803 -27.323 1.00 29.92 ? 376 HOH B O 1 HETATM 7992 O O . HOH W 8 . ? 5.049 82.102 -26.045 1.00 22.31 ? 377 HOH B O 1 HETATM 7993 O O . HOH W 8 . ? 7.491 64.055 -16.436 1.00 33.23 ? 378 HOH B O 1 HETATM 7994 O O . HOH W 8 . ? -12.097 65.944 -37.790 1.00 39.86 ? 379 HOH B O 1 HETATM 7995 O O . HOH W 8 . ? 8.013 80.605 -28.572 1.00 30.78 ? 380 HOH B O 1 HETATM 7996 O O . HOH W 8 . ? -14.841 63.092 8.273 1.00 39.16 ? 381 HOH B O 1 HETATM 7997 O O . HOH W 8 . ? -10.403 54.028 -14.486 1.00 44.33 ? 382 HOH B O 1 HETATM 7998 O O . HOH W 8 . ? 9.311 66.615 -14.557 1.00 43.23 ? 383 HOH B O 1 HETATM 7999 O O . HOH W 8 . ? -15.878 81.296 2.166 1.00 42.23 ? 384 HOH B O 1 HETATM 8000 O O . HOH W 8 . ? 1.817 69.980 -61.586 1.00 52.56 ? 385 HOH B O 1 HETATM 8001 O O . HOH W 8 . ? 2.744 76.683 -82.294 1.00 45.07 ? 386 HOH B O 1 HETATM 8002 O O . HOH W 8 . ? 4.824 60.275 -12.619 1.00 45.05 ? 387 HOH B O 1 HETATM 8003 O O . HOH W 8 . ? -14.645 74.117 -27.818 1.00 24.80 ? 388 HOH B O 1 HETATM 8004 O O . HOH W 8 . ? -13.130 71.485 -13.451 1.00 39.96 ? 389 HOH B O 1 HETATM 8005 O O . HOH W 8 . ? 8.079 69.677 -47.358 1.00 40.25 ? 390 HOH B O 1 HETATM 8006 O O . HOH W 8 . ? 0.887 69.430 -67.310 1.00 46.52 ? 391 HOH B O 1 HETATM 8007 O O . HOH W 8 . ? 3.852 63.734 -10.249 1.00 37.46 ? 392 HOH B O 1 HETATM 8008 O O . HOH W 8 . ? 8.374 72.117 -5.550 1.00 31.27 ? 393 HOH B O 1 HETATM 8009 O O . HOH W 8 . ? 7.393 77.748 -58.811 1.00 32.47 ? 394 HOH B O 1 HETATM 8010 O O . HOH W 8 . ? -0.051 76.367 1.913 1.00 39.34 ? 395 HOH B O 1 HETATM 8011 O O . HOH W 8 . ? -21.422 74.863 6.355 1.00 51.69 ? 396 HOH B O 1 HETATM 8012 O O . HOH W 8 . ? -13.571 74.019 -25.475 1.00 29.81 ? 397 HOH B O 1 HETATM 8013 O O . HOH W 8 . ? 6.967 70.331 -62.201 1.00 60.65 ? 398 HOH B O 1 HETATM 8014 O O . HOH W 8 . ? -6.471 53.522 -12.255 1.00 38.60 ? 399 HOH B O 1 HETATM 8015 O O . HOH W 8 . ? -5.178 77.183 -31.119 1.00 37.03 ? 400 HOH B O 1 HETATM 8016 O O . HOH W 8 . ? -3.182 60.718 3.355 1.00 46.39 ? 401 HOH B O 1 HETATM 8017 O O . HOH W 8 . ? 7.297 77.883 -55.802 1.00 33.62 ? 402 HOH B O 1 HETATM 8018 O O . HOH W 8 . ? -3.966 80.171 11.766 1.00 49.05 ? 403 HOH B O 1 HETATM 8019 O O . HOH W 8 . ? 7.307 73.396 -28.257 1.00 32.94 ? 404 HOH B O 1 HETATM 8020 O O . HOH W 8 . ? 1.367 73.952 8.842 1.00 36.19 ? 405 HOH B O 1 HETATM 8021 O O . HOH W 8 . ? -13.522 60.376 -2.894 1.00 38.04 ? 406 HOH B O 1 HETATM 8022 O O . HOH W 8 . ? -4.284 81.483 7.667 1.00 43.90 ? 407 HOH B O 1 HETATM 8023 O O . HOH W 8 . ? -5.302 56.369 2.636 1.00 45.81 ? 408 HOH B O 1 HETATM 8024 O O . HOH W 8 . ? -13.705 54.585 -0.342 1.00 49.48 ? 409 HOH B O 1 HETATM 8025 O O . HOH W 8 . ? -12.905 83.629 5.063 1.00 42.38 ? 410 HOH B O 1 HETATM 8026 O O . HOH W 8 . ? 2.761 71.491 -63.741 1.00 49.20 ? 411 HOH B O 1 HETATM 8027 O O . HOH W 8 . ? -0.211 76.248 -81.218 1.00 46.12 ? 412 HOH B O 1 HETATM 8028 O O . HOH W 8 . ? -17.895 56.709 -0.157 1.00 46.92 ? 413 HOH B O 1 HETATM 8029 O O . HOH W 8 . ? 6.503 64.624 -4.221 1.00 42.40 ? 414 HOH B O 1 HETATM 8030 O O . HOH W 8 . ? -13.192 79.666 11.838 1.00 41.00 ? 415 HOH B O 1 HETATM 8031 O O . HOH W 8 . ? -9.194 80.365 9.617 1.00 47.89 ? 416 HOH B O 1 HETATM 8032 O O . HOH W 8 . ? -21.213 70.283 -1.517 1.00 43.46 ? 417 HOH B O 1 HETATM 8033 O O . HOH W 8 . ? -12.939 69.087 -46.219 1.00 51.59 ? 418 HOH B O 1 HETATM 8034 O O . HOH W 8 . ? -18.276 68.813 8.786 1.00 50.82 ? 419 HOH B O 1 HETATM 8035 O O . HOH W 8 . ? -14.141 75.884 -7.784 1.00 37.43 ? 420 HOH B O 1 HETATM 8036 O O . HOH W 8 . ? 2.351 71.425 8.504 1.00 44.44 ? 421 HOH B O 1 HETATM 8037 O O . HOH W 8 . ? -2.863 68.151 8.836 1.00 42.90 ? 422 HOH B O 1 HETATM 8038 O O . HOH W 8 . ? 6.875 65.000 -7.008 1.00 52.63 ? 423 HOH B O 1 HETATM 8039 O O . HOH W 8 . ? -11.346 56.904 -6.481 1.00 41.96 ? 424 HOH B O 1 HETATM 8040 O O . HOH W 8 . ? 4.825 71.652 14.505 1.00 47.20 ? 425 HOH B O 1 HETATM 8041 O O . HOH W 8 . ? -15.126 80.865 7.612 1.00 43.40 ? 426 HOH B O 1 HETATM 8042 O O . HOH W 8 . ? -10.973 81.075 11.440 1.00 49.86 ? 427 HOH B O 1 HETATM 8043 O O . HOH W 8 . ? -6.302 77.325 18.959 1.00 52.32 ? 428 HOH B O 1 HETATM 8044 O O . HOH W 8 . ? -17.383 61.615 8.113 1.00 55.52 ? 429 HOH B O 1 HETATM 8045 O O . HOH W 8 . ? -16.551 76.964 -7.212 1.00 44.99 ? 430 HOH B O 1 HETATM 8046 O O . HOH W 8 . ? -20.902 77.605 4.376 1.00 55.85 ? 431 HOH B O 1 HETATM 8047 O O . HOH W 8 . ? -12.394 71.236 -8.565 1.00 34.46 ? 432 HOH B O 1 HETATM 8048 O O . HOH W 8 . ? -10.209 77.258 -19.149 1.00 45.75 ? 433 HOH B O 1 HETATM 8049 O O . HOH W 8 . ? 8.599 70.806 -49.949 1.00 42.83 ? 434 HOH B O 1 HETATM 8050 O O . HOH W 8 . ? -7.951 70.120 -68.933 1.00 51.13 ? 435 HOH B O 1 HETATM 8051 O O . HOH W 8 . ? -6.386 68.404 -67.838 1.00 47.45 ? 436 HOH B O 1 HETATM 8052 O O . HOH W 8 . ? -16.128 74.866 -24.392 1.00 53.81 ? 437 HOH B O 1 HETATM 8053 O O . HOH W 8 . ? -0.033 69.749 7.648 1.00 54.84 ? 438 HOH B O 1 HETATM 8054 O O . HOH W 8 . ? -9.930 69.875 -46.499 1.00 50.54 ? 439 HOH B O 1 HETATM 8055 O O . HOH W 8 . ? -12.772 82.185 8.361 1.00 49.76 ? 440 HOH B O 1 HETATM 8056 O O . HOH W 8 . ? 7.412 59.897 -13.477 1.00 60.56 ? 441 HOH B O 1 HETATM 8057 O O . HOH W 8 . ? -1.009 79.500 10.529 1.00 59.68 ? 442 HOH B O 1 HETATM 8058 O O . HOH W 8 . ? -5.559 82.552 4.817 1.00 47.14 ? 443 HOH B O 1 HETATM 8059 O O . HOH W 8 . ? -14.180 58.015 -3.535 1.00 52.96 ? 444 HOH B O 1 HETATM 8060 O O . HOH W 8 . ? -13.182 57.693 -10.214 1.00 51.61 ? 445 HOH B O 1 HETATM 8061 O O . HOH W 8 . ? 9.600 78.729 -58.291 1.00 47.69 ? 446 HOH B O 1 HETATM 8062 O O . HOH W 8 . ? -17.952 73.861 -32.671 1.00 45.83 ? 447 HOH B O 1 HETATM 8063 O O . HOH W 8 . ? -17.093 71.350 -22.929 1.00 41.77 ? 448 HOH B O 1 HETATM 8064 O O . HOH W 8 . ? -18.465 65.153 4.430 1.00 44.92 ? 449 HOH B O 1 HETATM 8065 O O . HOH W 8 . ? -19.696 72.060 -32.760 1.00 50.67 ? 450 HOH B O 1 HETATM 8066 O O . HOH W 8 . ? -12.847 55.656 -12.156 1.00 53.60 ? 451 HOH B O 1 HETATM 8067 O O . HOH W 8 . ? -13.676 58.820 -6.218 1.00 53.08 ? 452 HOH B O 1 HETATM 8068 O O . HOH W 8 . ? -9.157 60.114 10.012 1.00 62.72 ? 453 HOH B O 1 HETATM 8069 O O . HOH W 8 . ? 7.629 69.043 -72.240 1.00 51.90 ? 454 HOH B O 1 HETATM 8070 O O . HOH W 8 . ? -1.898 80.193 7.840 1.00 53.76 ? 455 HOH B O 1 HETATM 8071 O O . HOH W 8 . ? -17.224 74.371 -10.206 1.00 54.71 ? 456 HOH B O 1 HETATM 8072 O O . HOH W 8 . ? -20.111 70.731 0.704 1.00 47.10 ? 457 HOH B O 1 HETATM 8073 O O . HOH W 8 . ? 0.877 78.168 9.978 1.00 54.76 ? 458 HOH B O 1 HETATM 8074 O O . HOH W 8 . ? -5.975 53.330 -7.212 1.00 49.28 ? 459 HOH B O 1 HETATM 8075 O O . HOH W 8 . ? -6.449 82.448 2.686 1.00 60.23 ? 460 HOH B O 1 HETATM 8076 O O . HOH W 8 . ? -4.167 54.663 -5.457 1.00 38.98 ? 461 HOH B O 1 HETATM 8077 O O . HOH W 8 . ? -0.000 81.776 -24.178 0.33 21.12 ? 462 HOH B O 1 HETATM 8078 O O . HOH W 8 . ? 1.637 77.830 -27.029 1.00 28.67 ? 463 HOH B O 1 HETATM 8079 O O . HOH W 8 . ? -8.174 52.220 -1.275 1.00 42.76 ? 464 HOH B O 1 HETATM 8080 O O . HOH W 8 . ? 4.754 60.530 -16.705 1.00 38.52 ? 465 HOH B O 1 HETATM 8081 O O . HOH W 8 . ? -0.000 81.776 -15.990 0.33 31.80 ? 466 HOH B O 1 HETATM 8082 O O . HOH W 8 . ? 9.662 68.832 -13.086 1.00 38.38 ? 467 HOH B O 1 HETATM 8083 O O . HOH W 8 . ? -9.998 71.324 -61.020 1.00 50.81 ? 468 HOH B O 1 HETATM 8084 O O . HOH W 8 . ? 5.621 70.453 -20.245 1.00 33.47 ? 469 HOH B O 1 HETATM 8085 O O . HOH W 8 . ? 2.403 82.820 -25.983 1.00 33.24 ? 470 HOH B O 1 HETATM 8086 O O . HOH W 8 . ? -5.834 52.260 -20.446 1.00 38.35 ? 471 HOH B O 1 HETATM 8087 O O . HOH W 8 . ? -11.517 75.784 -25.088 1.00 41.74 ? 472 HOH B O 1 HETATM 8088 O O . HOH W 8 . ? 0.454 78.212 -5.886 1.00 36.53 ? 473 HOH B O 1 HETATM 8089 O O . HOH W 8 . ? 3.260 70.767 -59.732 1.00 46.91 ? 474 HOH B O 1 HETATM 8090 O O . HOH W 8 . ? 8.883 72.637 -83.715 1.00 50.07 ? 475 HOH B O 1 HETATM 8091 O O . HOH W 8 . ? -11.585 78.480 -10.002 1.00 34.38 ? 476 HOH B O 1 HETATM 8092 O O . HOH W 8 . ? 3.998 72.454 -23.705 1.00 36.10 ? 477 HOH B O 1 HETATM 8093 O O . HOH W 8 . ? -15.236 82.188 5.137 1.00 44.78 ? 478 HOH B O 1 HETATM 8094 O O . HOH W 8 . ? 1.245 63.838 -10.004 1.00 43.80 ? 479 HOH B O 1 HETATM 8095 O O . HOH W 8 . ? 9.015 74.021 -68.053 1.00 41.95 ? 480 HOH B O 1 HETATM 8096 O O . HOH W 8 . ? -4.161 74.367 -62.593 1.00 43.88 ? 481 HOH B O 1 HETATM 8097 O O . HOH W 8 . ? 7.234 74.679 -46.637 1.00 36.93 ? 482 HOH B O 1 HETATM 8098 O O . HOH W 8 . ? -13.115 73.460 -16.906 1.00 42.69 ? 483 HOH B O 1 HETATM 8099 O O . HOH W 8 . ? -7.115 67.495 11.416 1.00 44.01 ? 484 HOH B O 1 HETATM 8100 O O . HOH W 8 . ? 6.981 71.751 -74.856 1.00 45.93 ? 485 HOH B O 1 HETATM 8101 O O . HOH W 8 . ? -18.450 77.276 -4.045 1.00 52.14 ? 486 HOH B O 1 HETATM 8102 O O . HOH W 8 . ? -21.437 62.636 -17.044 1.00 45.05 ? 487 HOH B O 1 HETATM 8103 O O . HOH W 8 . ? -17.196 74.694 -27.916 1.00 44.31 ? 488 HOH B O 1 HETATM 8104 O O . HOH W 8 . ? -22.631 63.428 -19.514 1.00 45.33 ? 489 HOH B O 1 HETATM 8105 O O . HOH W 8 . ? 6.000 73.205 -82.883 1.00 43.14 ? 490 HOH B O 1 HETATM 8106 O O . HOH W 8 . ? 7.657 73.907 -16.754 1.00 45.85 ? 491 HOH B O 1 HETATM 8107 O O . HOH W 8 . ? -15.085 78.193 -42.741 1.00 50.01 ? 492 HOH B O 1 HETATM 8108 O O . HOH W 8 . ? -15.114 64.876 10.549 1.00 49.02 ? 493 HOH B O 1 HETATM 8109 O O . HOH W 8 . ? -15.198 59.633 -8.173 1.00 50.73 ? 494 HOH B O 1 HETATM 8110 O O . HOH W 8 . ? 4.472 75.035 -83.828 1.00 48.61 ? 495 HOH B O 1 HETATM 8111 O O . HOH W 8 . ? -2.081 81.158 -10.508 1.00 48.11 ? 496 HOH B O 1 HETATM 8112 O O . HOH W 8 . ? -19.611 73.686 -9.056 1.00 54.47 ? 497 HOH B O 1 HETATM 8113 O O . HOH W 8 . ? -17.848 79.537 0.558 1.00 48.78 ? 498 HOH B O 1 HETATM 8114 O O . HOH W 8 . ? -0.124 79.836 -2.661 1.00 53.88 ? 499 HOH B O 1 HETATM 8115 O O . HOH W 8 . ? -20.570 65.586 -8.095 1.00 52.72 ? 500 HOH B O 1 HETATM 8116 O O . HOH W 8 . ? 3.115 67.764 -76.044 1.00 51.62 ? 501 HOH B O 1 HETATM 8117 O O . HOH W 8 . ? -14.391 74.501 -38.665 1.00 43.32 ? 502 HOH B O 1 HETATM 8118 O O . HOH W 8 . ? 9.056 75.443 -59.726 1.00 52.78 ? 503 HOH B O 1 HETATM 8119 O O . HOH W 8 . ? -14.119 73.924 -36.313 1.00 47.63 ? 504 HOH B O 1 HETATM 8120 O O . HOH W 8 . ? 5.245 56.621 -14.387 1.00 54.34 ? 505 HOH B O 1 HETATM 8121 O O . HOH W 8 . ? 6.092 69.165 -76.480 1.00 53.23 ? 506 HOH B O 1 HETATM 8122 O O . HOH W 8 . ? 2.129 82.747 -40.151 1.00 46.00 ? 507 HOH B O 1 HETATM 8123 O O . HOH W 8 . ? -16.991 66.617 9.800 1.00 53.86 ? 508 HOH B O 1 HETATM 8124 O O . HOH W 8 . ? -5.116 50.811 -17.881 1.00 53.80 ? 509 HOH B O 1 HETATM 8125 O O . HOH W 8 . ? -13.597 58.314 7.217 1.00 52.75 ? 510 HOH B O 1 HETATM 8126 O O . HOH W 8 . ? -2.926 79.465 2.235 1.00 52.25 ? 511 HOH B O 1 HETATM 8127 O O . HOH W 8 . ? -0.028 78.259 -0.045 1.00 57.57 ? 512 HOH B O 1 HETATM 8128 O O . HOH W 8 . ? 7.843 71.235 -68.108 1.00 55.61 ? 513 HOH B O 1 HETATM 8129 O O . HOH W 8 . ? -13.061 73.559 -14.324 1.00 55.91 ? 514 HOH B O 1 HETATM 8130 O O . HOH W 8 . ? -0.000 81.776 -47.553 0.33 28.92 ? 515 HOH B O 1 HETATM 8131 O O . HOH W 8 . ? 2.948 79.410 -28.825 1.00 36.69 ? 516 HOH B O 1 HETATM 8132 O O . HOH W 8 . ? -0.382 71.326 -65.679 1.00 36.38 ? 517 HOH B O 1 HETATM 8133 O O . HOH W 8 . ? 8.016 67.516 -3.017 1.00 61.27 ? 518 HOH B O 1 HETATM 8134 O O . HOH W 8 . ? 8.884 72.247 -46.213 1.00 55.52 ? 519 HOH B O 1 HETATM 8135 O O . HOH W 8 . ? -13.718 77.109 -45.047 1.00 54.53 ? 520 HOH B O 1 HETATM 8136 O O . HOH W 8 . ? -0.000 81.776 -40.000 0.33 54.35 ? 521 HOH B O 1 HETATM 8137 O O . HOH W 8 . ? 8.140 67.640 -6.819 1.00 57.72 ? 522 HOH B O 1 HETATM 8138 O O . HOH W 8 . ? 4.232 61.474 -10.351 1.00 53.76 ? 523 HOH B O 1 HETATM 8139 O O . HOH W 8 . ? -5.033 80.944 0.592 1.00 53.21 ? 524 HOH B O 1 HETATM 8140 O O . HOH W 8 . ? -5.374 81.948 -12.836 1.00 45.97 ? 525 HOH B O 1 HETATM 8141 O O . HOH W 8 . ? 5.923 69.025 -74.066 1.00 61.06 ? 526 HOH B O 1 HETATM 8142 O O . HOH W 8 . ? -13.913 76.231 -13.115 1.00 55.89 ? 527 HOH B O 1 HETATM 8143 O O . HOH W 8 . ? -15.689 61.890 -9.065 1.00 56.98 ? 528 HOH B O 1 HETATM 8144 O O . HOH W 8 . ? -8.612 65.641 14.640 1.00 54.92 ? 529 HOH B O 1 HETATM 8145 O O . HOH W 8 . ? -14.396 85.926 5.458 1.00 55.48 ? 530 HOH B O 1 HETATM 8146 O O . HOH W 8 . ? -0.000 81.776 -4.937 0.33 56.42 ? 531 HOH B O 1 HETATM 8147 O O . HOH W 8 . ? -16.146 72.874 -35.570 1.00 51.46 ? 532 HOH B O 1 HETATM 8148 O O . HOH W 8 . ? -18.572 60.960 -2.788 1.00 56.49 ? 533 HOH B O 1 HETATM 8149 O O . HOH W 8 . ? -11.161 54.461 -7.037 1.00 56.23 ? 534 HOH B O 1 HETATM 8150 O O . HOH W 8 . ? 9.667 74.725 -15.750 1.00 59.84 ? 535 HOH B O 1 HETATM 8151 O O . HOH W 8 . ? -15.071 85.218 7.641 1.00 57.50 ? 536 HOH B O 1 HETATM 8152 O O . HOH W 8 . ? -14.854 62.110 -12.444 1.00 51.33 ? 537 HOH B O 1 HETATM 8153 O O . HOH W 8 . ? -13.123 54.468 10.976 1.00 53.20 ? 538 HOH B O 1 HETATM 8154 O O . HOH W 8 . ? -23.600 61.956 -2.423 1.00 55.86 ? 539 HOH B O 1 HETATM 8155 O O . HOH W 8 . ? -17.016 73.294 -18.958 1.00 59.29 ? 540 HOH B O 1 HETATM 8156 O O . HOH W 8 . ? -17.388 60.022 -4.987 1.00 61.40 ? 541 HOH B O 1 HETATM 8157 O O . HOH W 8 . ? -19.217 69.108 -19.144 1.00 53.67 ? 542 HOH B O 1 HETATM 8158 O O . HOH X 8 . ? -29.848 45.547 -40.552 1.00 21.80 ? 401 HOH H O 1 HETATM 8159 O O . HOH X 8 . ? -28.808 48.271 -40.687 1.00 21.92 ? 402 HOH H O 1 HETATM 8160 O O . HOH X 8 . ? -13.157 61.787 -27.941 1.00 19.72 ? 403 HOH H O 1 HETATM 8161 O O . HOH X 8 . ? -29.643 58.414 -34.525 1.00 25.53 ? 404 HOH H O 1 HETATM 8162 O O . HOH X 8 . ? -30.344 56.234 -38.093 1.00 27.79 ? 405 HOH H O 1 HETATM 8163 O O . HOH X 8 . ? -30.180 46.507 -44.449 1.00 29.10 ? 406 HOH H O 1 HETATM 8164 O O . HOH X 8 . ? -31.442 58.114 -30.828 1.00 24.86 ? 407 HOH H O 1 HETATM 8165 O O . HOH X 8 . ? -12.915 48.127 -36.295 1.00 22.57 ? 408 HOH H O 1 HETATM 8166 O O . HOH X 8 . ? -25.073 39.129 -26.372 1.00 27.75 ? 409 HOH H O 1 HETATM 8167 O O . HOH X 8 . ? -16.985 58.892 -31.183 1.00 23.77 ? 410 HOH H O 1 HETATM 8168 O O . HOH X 8 . ? -9.298 53.894 -34.494 1.00 23.14 ? 411 HOH H O 1 HETATM 8169 O O . HOH X 8 . ? -27.543 52.363 -44.100 1.00 45.50 ? 412 HOH H O 1 HETATM 8170 O O . HOH X 8 . ? -12.650 35.784 -38.603 1.00 29.00 ? 413 HOH H O 1 HETATM 8171 O O . HOH X 8 . ? -24.389 49.026 -45.849 1.00 35.70 ? 414 HOH H O 1 HETATM 8172 O O . HOH X 8 . ? -30.474 31.980 -40.809 1.00 31.56 ? 415 HOH H O 1 HETATM 8173 O O . HOH X 8 . ? -30.705 49.876 -41.970 1.00 28.73 ? 416 HOH H O 1 HETATM 8174 O O . HOH X 8 . ? -18.909 59.065 -18.949 1.00 22.30 ? 417 HOH H O 1 HETATM 8175 O O . HOH X 8 . ? -24.642 62.429 -26.900 1.00 26.46 ? 418 HOH H O 1 HETATM 8176 O O . HOH X 8 . ? -19.303 33.104 -31.265 1.00 25.45 ? 419 HOH H O 1 HETATM 8177 O O . HOH X 8 . ? -23.176 46.265 -41.881 1.00 23.28 ? 420 HOH H O 1 HETATM 8178 O O . HOH X 8 . ? -23.320 54.212 -20.208 1.00 26.18 ? 421 HOH H O 1 HETATM 8179 O O . HOH X 8 . ? -11.055 46.685 -37.767 1.00 29.47 ? 422 HOH H O 1 HETATM 8180 O O . HOH X 8 . ? -32.298 58.413 -26.378 1.00 23.34 ? 423 HOH H O 1 HETATM 8181 O O . HOH X 8 . ? -27.667 34.356 -31.541 1.00 26.62 ? 424 HOH H O 1 HETATM 8182 O O . HOH X 8 . ? -20.836 42.547 -22.241 1.00 27.83 ? 425 HOH H O 1 HETATM 8183 O O . HOH X 8 . ? -11.230 50.891 -39.095 1.00 27.05 ? 426 HOH H O 1 HETATM 8184 O O . HOH X 8 . ? -14.980 58.977 -35.430 1.00 26.60 ? 427 HOH H O 1 HETATM 8185 O O . HOH X 8 . ? -27.910 39.836 -26.247 1.00 25.92 ? 428 HOH H O 1 HETATM 8186 O O . HOH X 8 . ? -16.867 57.972 -33.818 1.00 30.90 ? 429 HOH H O 1 HETATM 8187 O O . HOH X 8 . ? -29.977 29.475 -41.791 1.00 30.79 ? 430 HOH H O 1 HETATM 8188 O O . HOH X 8 . ? -10.650 47.703 -22.482 1.00 34.69 ? 431 HOH H O 1 HETATM 8189 O O . HOH X 8 . ? -33.086 44.023 -31.394 1.00 32.42 ? 432 HOH H O 1 HETATM 8190 O O . HOH X 8 . ? -7.528 53.137 -24.705 1.00 27.72 ? 433 HOH H O 1 HETATM 8191 O O . HOH X 8 . ? -22.753 53.777 -42.004 1.00 33.88 ? 434 HOH H O 1 HETATM 8192 O O . HOH X 8 . ? -17.994 61.373 -35.438 1.00 22.70 ? 435 HOH H O 1 HETATM 8193 O O . HOH X 8 . ? -24.553 31.396 -45.122 1.00 32.04 ? 436 HOH H O 1 HETATM 8194 O O . HOH X 8 . ? -32.246 54.917 -34.040 1.00 30.71 ? 437 HOH H O 1 HETATM 8195 O O . HOH X 8 . ? -40.734 34.224 -38.118 1.00 38.21 ? 438 HOH H O 1 HETATM 8196 O O . HOH X 8 . ? -30.230 53.880 -43.504 1.00 56.88 ? 439 HOH H O 1 HETATM 8197 O O . HOH X 8 . ? -37.748 33.224 -39.761 1.00 39.67 ? 440 HOH H O 1 HETATM 8198 O O . HOH X 8 . ? -24.044 33.263 -47.130 1.00 30.42 ? 441 HOH H O 1 HETATM 8199 O O . HOH X 8 . ? -18.622 56.302 -43.381 1.00 34.05 ? 442 HOH H O 1 HETATM 8200 O O . HOH X 8 . ? -9.929 54.084 -21.736 1.00 33.20 ? 443 HOH H O 1 HETATM 8201 O O . HOH X 8 . ? -34.289 50.886 -35.613 1.00 39.11 ? 444 HOH H O 1 HETATM 8202 O O . HOH X 8 . ? -20.811 29.013 -30.913 1.00 30.01 ? 445 HOH H O 1 HETATM 8203 O O . HOH X 8 . ? -25.620 34.714 -27.952 1.00 32.09 ? 446 HOH H O 1 HETATM 8204 O O . HOH X 8 . ? -25.252 60.308 -17.625 1.00 28.59 ? 447 HOH H O 1 HETATM 8205 O O . HOH X 8 . ? -16.341 32.440 -31.801 1.00 31.79 ? 448 HOH H O 1 HETATM 8206 O O . HOH X 8 . ? -28.930 39.723 -41.368 1.00 27.32 ? 449 HOH H O 1 HETATM 8207 O O . HOH X 8 . ? -27.895 32.072 -36.624 1.00 27.65 ? 450 HOH H O 1 HETATM 8208 O O . HOH X 8 . ? -31.152 55.028 -40.452 1.00 33.47 ? 451 HOH H O 1 HETATM 8209 O O . HOH X 8 . ? -30.270 32.266 -37.977 1.00 36.11 ? 452 HOH H O 1 HETATM 8210 O O . HOH X 8 . ? -21.580 27.404 -45.980 1.00 31.97 ? 453 HOH H O 1 HETATM 8211 O O . HOH X 8 . ? -26.434 61.280 -21.225 1.00 36.04 ? 454 HOH H O 1 HETATM 8212 O O . HOH X 8 . ? -39.084 30.136 -37.416 1.00 39.06 ? 455 HOH H O 1 HETATM 8213 O O . HOH X 8 . ? -26.918 29.826 -31.300 1.00 50.10 ? 456 HOH H O 1 HETATM 8214 O O . HOH X 8 . ? -25.553 23.972 -43.797 1.00 33.78 ? 457 HOH H O 1 HETATM 8215 O O . HOH X 8 . ? -31.155 61.856 -28.781 1.00 40.87 ? 458 HOH H O 1 HETATM 8216 O O . HOH X 8 . ? -41.553 24.635 -46.271 1.00 52.34 ? 459 HOH H O 1 HETATM 8217 O O . HOH X 8 . ? -8.221 48.541 -30.232 1.00 31.74 ? 460 HOH H O 1 HETATM 8218 O O . HOH X 8 . ? -31.488 35.304 -43.368 1.00 32.92 ? 461 HOH H O 1 HETATM 8219 O O . HOH X 8 . ? -24.497 65.683 -23.467 1.00 35.00 ? 462 HOH H O 1 HETATM 8220 O O . HOH X 8 . ? -37.177 35.788 -40.628 1.00 41.16 ? 463 HOH H O 1 HETATM 8221 O O . HOH X 8 . ? -33.687 34.273 -39.216 1.00 35.12 ? 464 HOH H O 1 HETATM 8222 O O . HOH X 8 . ? -9.266 58.490 -36.948 1.00 35.29 ? 465 HOH H O 1 HETATM 8223 O O . HOH X 8 . ? -20.925 64.067 -40.499 1.00 40.21 ? 466 HOH H O 1 HETATM 8224 O O . HOH X 8 . ? -20.680 35.180 -28.113 1.00 36.77 ? 467 HOH H O 1 HETATM 8225 O O . HOH X 8 . ? -7.438 54.118 -28.395 1.00 38.01 ? 468 HOH H O 1 HETATM 8226 O O . HOH X 8 . ? -13.085 45.451 -19.757 1.00 41.77 ? 469 HOH H O 1 HETATM 8227 O O . HOH X 8 . ? -30.580 39.667 -43.592 1.00 43.51 ? 470 HOH H O 1 HETATM 8228 O O . HOH X 8 . ? -18.092 42.965 -43.063 1.00 40.67 ? 471 HOH H O 1 HETATM 8229 O O . HOH X 8 . ? -10.845 53.344 -40.283 1.00 43.40 ? 472 HOH H O 1 HETATM 8230 O O . HOH X 8 . ? -15.366 66.096 -38.343 1.00 38.62 ? 473 HOH H O 1 HETATM 8231 O O . HOH X 8 . ? -33.878 39.422 -58.169 1.00 54.74 ? 474 HOH H O 1 HETATM 8232 O O . HOH X 8 . ? -17.288 41.381 -19.901 1.00 33.49 ? 475 HOH H O 1 HETATM 8233 O O . HOH X 8 . ? -9.230 55.200 -39.241 1.00 45.05 ? 476 HOH H O 1 HETATM 8234 O O . HOH X 8 . ? -8.279 57.659 -39.608 1.00 47.82 ? 477 HOH H O 1 HETATM 8235 O O . HOH X 8 . ? -10.191 42.720 -36.122 1.00 34.31 ? 478 HOH H O 1 HETATM 8236 O O . HOH X 8 . ? -26.304 34.162 -48.513 1.00 39.07 ? 479 HOH H O 1 HETATM 8237 O O . HOH X 8 . ? -34.889 41.113 -27.476 1.00 40.30 ? 480 HOH H O 1 HETATM 8238 O O . HOH X 8 . ? -45.925 41.547 -49.801 1.00 42.63 ? 481 HOH H O 1 HETATM 8239 O O . HOH X 8 . ? -33.469 47.894 -34.585 1.00 36.96 ? 482 HOH H O 1 HETATM 8240 O O . HOH X 8 . ? -12.350 53.370 -16.571 1.00 46.17 ? 483 HOH H O 1 HETATM 8241 O O . HOH X 8 . ? -28.950 26.151 -49.984 1.00 35.29 ? 484 HOH H O 1 HETATM 8242 O O . HOH X 8 . ? -31.756 34.551 -37.371 1.00 36.48 ? 485 HOH H O 1 HETATM 8243 O O . HOH X 8 . ? -31.448 30.828 -35.986 1.00 47.19 ? 486 HOH H O 1 HETATM 8244 O O . HOH X 8 . ? -20.290 27.622 -43.712 1.00 24.15 ? 487 HOH H O 1 HETATM 8245 O O . HOH X 8 . ? -8.791 55.826 -29.814 1.00 41.82 ? 488 HOH H O 1 HETATM 8246 O O . HOH X 8 . ? -19.211 34.890 -44.998 1.00 23.86 ? 489 HOH H O 1 HETATM 8247 O O . HOH X 8 . ? -18.329 63.336 -42.561 1.00 43.60 ? 490 HOH H O 1 HETATM 8248 O O . HOH X 8 . ? -14.706 37.298 -43.393 1.00 34.69 ? 491 HOH H O 1 HETATM 8249 O O . HOH X 8 . ? -31.000 37.179 -37.832 1.00 33.29 ? 492 HOH H O 1 HETATM 8250 O O . HOH X 8 . ? -23.693 66.685 -31.548 1.00 37.46 ? 493 HOH H O 1 HETATM 8251 O O . HOH X 8 . ? -30.179 63.464 -23.923 1.00 45.80 ? 494 HOH H O 1 HETATM 8252 O O . HOH X 8 . ? -32.430 41.154 -31.514 1.00 35.84 ? 495 HOH H O 1 HETATM 8253 O O . HOH X 8 . ? -12.777 65.484 -42.671 1.00 33.58 ? 496 HOH H O 1 HETATM 8254 O O . HOH X 8 . ? -26.713 64.576 -23.688 1.00 43.54 ? 497 HOH H O 1 HETATM 8255 O O . HOH X 8 . ? -7.185 58.459 -23.410 1.00 34.96 ? 498 HOH H O 1 HETATM 8256 O O . HOH X 8 . ? -13.256 40.366 -13.898 1.00 54.86 ? 499 HOH H O 1 HETATM 8257 O O . HOH X 8 . ? -34.602 40.529 -29.902 1.00 47.60 ? 500 HOH H O 1 HETATM 8258 O O . HOH X 8 . ? -24.001 31.056 -49.755 1.00 41.20 ? 501 HOH H O 1 HETATM 8259 O O . HOH X 8 . ? -19.956 67.581 -31.474 1.00 35.39 ? 502 HOH H O 1 HETATM 8260 O O . HOH X 8 . ? -31.097 28.964 -56.537 1.00 48.72 ? 503 HOH H O 1 HETATM 8261 O O . HOH X 8 . ? -48.183 42.039 -45.748 1.00 51.40 ? 504 HOH H O 1 HETATM 8262 O O . HOH X 8 . ? -38.649 38.081 -46.402 1.00 42.90 ? 505 HOH H O 1 HETATM 8263 O O . HOH X 8 . ? -27.027 66.540 -31.800 1.00 52.58 ? 506 HOH H O 1 HETATM 8264 O O . HOH X 8 . ? -35.578 39.371 -23.056 1.00 51.88 ? 507 HOH H O 1 HETATM 8265 O O . HOH X 8 . ? -27.057 64.708 -27.711 1.00 41.72 ? 508 HOH H O 1 HETATM 8266 O O . HOH X 8 . ? -9.725 51.065 -21.921 1.00 55.76 ? 509 HOH H O 1 HETATM 8267 O O . HOH X 8 . ? -19.877 69.023 -36.066 1.00 46.10 ? 510 HOH H O 1 HETATM 8268 O O . HOH X 8 . ? -26.512 41.380 -46.662 1.00 45.42 ? 511 HOH H O 1 HETATM 8269 O O . HOH X 8 . ? -19.201 58.638 -35.374 1.00 38.42 ? 512 HOH H O 1 HETATM 8270 O O . HOH X 8 . ? -17.518 67.742 -38.448 1.00 48.22 ? 513 HOH H O 1 HETATM 8271 O O . HOH X 8 . ? -20.667 68.769 -28.984 1.00 36.83 ? 514 HOH H O 1 HETATM 8272 O O . HOH X 8 . ? -19.787 33.069 -28.593 1.00 33.79 ? 515 HOH H O 1 HETATM 8273 O O . HOH X 8 . ? -48.710 43.843 -54.518 1.00 48.03 ? 516 HOH H O 1 HETATM 8274 O O . HOH X 8 . ? -22.281 35.417 -46.674 1.00 42.38 ? 517 HOH H O 1 HETATM 8275 O O . HOH X 8 . ? -30.886 37.775 -42.229 1.00 39.85 ? 518 HOH H O 1 HETATM 8276 O O . HOH X 8 . ? -34.640 40.003 -52.089 1.00 47.78 ? 519 HOH H O 1 HETATM 8277 O O . HOH X 8 . ? -25.239 28.999 -53.474 1.00 40.64 ? 520 HOH H O 1 HETATM 8278 O O . HOH X 8 . ? -24.289 61.370 -43.833 1.00 49.28 ? 521 HOH H O 1 HETATM 8279 O O . HOH X 8 . ? -27.499 68.989 -37.327 1.00 45.05 ? 522 HOH H O 1 HETATM 8280 O O . HOH X 8 . ? -30.810 60.788 -33.549 1.00 41.70 ? 523 HOH H O 1 HETATM 8281 O O . HOH X 8 . ? -18.466 58.339 -45.135 1.00 43.51 ? 524 HOH H O 1 HETATM 8282 O O . HOH X 8 . ? -14.538 42.049 -41.524 1.00 40.24 ? 525 HOH H O 1 HETATM 8283 O O . HOH X 8 . ? -39.957 36.928 -43.152 1.00 42.47 ? 526 HOH H O 1 HETATM 8284 O O . HOH X 8 . ? -17.095 54.063 -43.703 1.00 42.74 ? 527 HOH H O 1 HETATM 8285 O O . HOH X 8 . ? -22.915 53.771 -16.751 1.00 37.20 ? 528 HOH H O 1 HETATM 8286 O O . HOH X 8 . ? -39.057 42.093 -47.654 1.00 53.72 ? 529 HOH H O 1 HETATM 8287 O O . HOH X 8 . ? -8.955 51.407 -31.514 1.00 43.18 ? 530 HOH H O 1 HETATM 8288 O O . HOH X 8 . ? -32.292 26.232 -38.539 1.00 43.52 ? 531 HOH H O 1 HETATM 8289 O O . HOH X 8 . ? -19.642 41.994 -45.063 1.00 42.05 ? 532 HOH H O 1 HETATM 8290 O O . HOH X 8 . ? -6.949 38.102 -30.543 1.00 54.15 ? 533 HOH H O 1 HETATM 8291 O O . HOH X 8 . ? -32.517 42.452 -41.310 1.00 43.50 ? 534 HOH H O 1 HETATM 8292 O O . HOH X 8 . ? -34.679 60.416 -31.256 1.00 60.80 ? 535 HOH H O 1 HETATM 8293 O O . HOH X 8 . ? -35.011 43.888 -35.410 1.00 47.11 ? 536 HOH H O 1 HETATM 8294 O O . HOH X 8 . ? -48.434 40.065 -62.226 1.00 50.27 ? 537 HOH H O 1 HETATM 8295 O O . HOH X 8 . ? -35.308 57.983 -33.482 1.00 53.69 ? 538 HOH H O 1 HETATM 8296 O O . HOH X 8 . ? -17.314 37.219 -45.115 1.00 59.46 ? 539 HOH H O 1 HETATM 8297 O O . HOH X 8 . ? -39.549 22.706 -47.035 1.00 47.80 ? 540 HOH H O 1 HETATM 8298 O O . HOH X 8 . ? -55.295 38.463 -46.815 1.00 59.07 ? 541 HOH H O 1 HETATM 8299 O O . HOH X 8 . ? -10.124 41.159 -32.507 1.00 43.63 ? 542 HOH H O 1 HETATM 8300 O O . HOH X 8 . ? -30.081 39.468 -48.059 1.00 41.78 ? 543 HOH H O 1 HETATM 8301 O O . HOH X 8 . ? -13.858 67.572 -43.803 1.00 56.48 ? 544 HOH H O 1 HETATM 8302 O O . HOH X 8 . ? -23.197 39.709 -20.703 1.00 49.18 ? 545 HOH H O 1 HETATM 8303 O O . HOH X 8 . ? -8.137 44.070 -31.927 1.00 47.43 ? 546 HOH H O 1 HETATM 8304 O O . HOH X 8 . ? -21.994 28.292 -49.567 1.00 45.73 ? 547 HOH H O 1 HETATM 8305 O O . HOH X 8 . ? -33.047 42.094 -50.889 1.00 55.32 ? 548 HOH H O 1 HETATM 8306 O O . HOH X 8 . ? -32.582 41.332 -43.686 1.00 48.24 ? 549 HOH H O 1 HETATM 8307 O O . HOH X 8 . ? -9.968 35.812 -30.674 1.00 55.73 ? 550 HOH H O 1 HETATM 8308 O O . HOH X 8 . ? -10.885 39.237 -21.278 1.00 50.07 ? 551 HOH H O 1 HETATM 8309 O O . HOH X 8 . ? -35.597 22.432 -46.294 1.00 46.74 ? 552 HOH H O 1 HETATM 8310 O O . HOH X 8 . ? -30.578 39.029 -35.469 1.00 39.88 ? 553 HOH H O 1 HETATM 8311 O O . HOH X 8 . ? -27.916 25.941 -40.729 1.00 51.20 ? 554 HOH H O 1 HETATM 8312 O O . HOH X 8 . ? -25.356 59.072 -43.264 1.00 41.51 ? 555 HOH H O 1 HETATM 8313 O O . HOH X 8 . ? -34.756 55.135 -37.712 1.00 43.74 ? 556 HOH H O 1 HETATM 8314 O O . HOH X 8 . ? -33.994 45.703 -33.544 1.00 36.36 ? 557 HOH H O 1 HETATM 8315 O O . HOH X 8 . ? -33.151 38.012 -41.076 1.00 51.35 ? 558 HOH H O 1 HETATM 8316 O O . HOH X 8 . ? -32.316 55.968 -36.393 1.00 44.11 ? 559 HOH H O 1 HETATM 8317 O O . HOH X 8 . ? -31.665 60.957 -31.209 1.00 44.93 ? 560 HOH H O 1 HETATM 8318 O O . HOH X 8 . ? -27.601 38.566 -48.867 1.00 48.13 ? 561 HOH H O 1 HETATM 8319 O O . HOH X 8 . ? -47.696 44.293 -51.891 1.00 59.40 ? 562 HOH H O 1 HETATM 8320 O O . HOH X 8 . ? -32.239 44.834 -41.420 1.00 43.95 ? 563 HOH H O 1 HETATM 8321 O O . HOH X 8 . ? -32.538 45.408 -44.074 1.00 40.97 ? 564 HOH H O 1 HETATM 8322 O O . HOH X 8 . ? -33.048 56.843 -32.845 1.00 47.87 ? 565 HOH H O 1 HETATM 8323 O O . HOH X 8 . ? -29.956 40.777 -46.129 1.00 51.21 ? 566 HOH H O 1 HETATM 8324 O O . HOH X 8 . ? -26.070 36.884 -48.919 1.00 53.27 ? 567 HOH H O 1 HETATM 8325 O O . HOH X 8 . ? -30.528 43.277 -47.082 1.00 55.38 ? 568 HOH H O 1 HETATM 8326 O O . HOH X 8 . ? -17.965 59.391 -13.026 1.00 44.09 ? 569 HOH H O 1 HETATM 8327 O O . HOH X 8 . ? -19.817 60.492 -16.199 1.00 33.60 ? 570 HOH H O 1 HETATM 8328 O O . HOH X 8 . ? -23.112 40.523 -45.544 1.00 35.24 ? 571 HOH H O 1 HETATM 8329 O O . HOH X 8 . ? -27.967 33.668 -29.050 1.00 40.57 ? 572 HOH H O 1 HETATM 8330 O O . HOH X 8 . ? -26.196 27.195 -40.006 1.00 39.99 ? 573 HOH H O 1 HETATM 8331 O O . HOH X 8 . ? -10.232 34.898 -38.363 1.00 48.03 ? 574 HOH H O 1 HETATM 8332 O O . HOH X 8 . ? -36.088 33.067 -37.832 1.00 40.41 ? 575 HOH H O 1 HETATM 8333 O O . HOH X 8 . ? -7.682 49.336 -34.834 1.00 43.25 ? 576 HOH H O 1 HETATM 8334 O O . HOH X 8 . ? -32.812 43.353 -45.577 1.00 48.73 ? 577 HOH H O 1 HETATM 8335 O O . HOH X 8 . ? -30.256 49.299 -44.550 1.00 43.30 ? 578 HOH H O 1 HETATM 8336 O O . HOH X 8 . ? -21.255 55.234 -43.782 1.00 45.47 ? 579 HOH H O 1 HETATM 8337 O O . HOH X 8 . ? -28.289 25.179 -52.241 1.00 50.91 ? 580 HOH H O 1 HETATM 8338 O O . HOH X 8 . ? -22.529 38.809 -47.159 1.00 45.89 ? 581 HOH H O 1 HETATM 8339 O O . HOH X 8 . ? -41.445 23.996 -44.154 1.00 57.11 ? 582 HOH H O 1 HETATM 8340 O O . HOH X 8 . ? -8.637 47.847 -37.205 1.00 49.88 ? 583 HOH H O 1 HETATM 8341 O O . HOH X 8 . ? -8.678 50.493 -38.742 1.00 44.99 ? 584 HOH H O 1 HETATM 8342 O O . HOH X 8 . ? -20.357 44.059 -49.610 1.00 45.24 ? 585 HOH H O 1 HETATM 8343 O O . HOH X 8 . ? -33.249 49.416 -41.115 1.00 45.26 ? 586 HOH H O 1 HETATM 8344 O O . HOH X 8 . ? -24.252 52.943 -44.520 1.00 47.47 ? 587 HOH H O 1 HETATM 8345 O O . HOH X 8 . ? -6.850 49.191 -28.165 1.00 43.64 ? 588 HOH H O 1 HETATM 8346 O O . HOH X 8 . ? -8.003 53.711 -37.105 1.00 48.85 ? 589 HOH H O 1 HETATM 8347 O O . HOH X 8 . ? -19.559 45.050 -43.796 1.00 49.38 ? 590 HOH H O 1 HETATM 8348 O O . HOH X 8 . ? -24.440 56.958 -44.108 1.00 45.82 ? 591 HOH H O 1 HETATM 8349 O O . HOH X 8 . ? -20.919 29.473 -51.697 1.00 52.93 ? 592 HOH H O 1 HETATM 8350 O O . HOH X 8 . ? -28.939 31.111 -34.161 1.00 45.15 ? 593 HOH H O 1 HETATM 8351 O O . HOH X 8 . ? -30.081 32.943 -32.780 1.00 45.80 ? 594 HOH H O 1 HETATM 8352 O O . HOH X 8 . ? -12.606 51.969 -44.008 1.00 63.68 ? 595 HOH H O 1 HETATM 8353 O O . HOH X 8 . ? -33.861 53.857 -39.856 1.00 50.18 ? 596 HOH H O 1 HETATM 8354 O O . HOH X 8 . ? -36.093 31.040 -35.975 1.00 50.47 ? 597 HOH H O 1 HETATM 8355 O O . HOH X 8 . ? -10.285 40.322 -39.309 1.00 52.63 ? 598 HOH H O 1 HETATM 8356 O O . HOH X 8 . ? -16.851 38.897 -18.148 1.00 52.26 ? 599 HOH H O 1 HETATM 8357 O O . HOH X 8 . ? -13.056 49.811 -43.030 1.00 48.87 ? 600 HOH H O 1 HETATM 8358 O O . HOH X 8 . ? -28.246 26.791 -54.131 1.00 54.15 ? 601 HOH H O 1 HETATM 8359 O O . HOH X 8 . ? -38.003 20.743 -49.782 1.00 56.98 ? 602 HOH H O 1 HETATM 8360 O O . HOH X 8 . ? -19.802 38.195 -47.114 1.00 57.52 ? 603 HOH H O 1 HETATM 8361 O O . HOH X 8 . ? -26.873 32.839 -56.169 1.00 52.76 ? 604 HOH H O 1 HETATM 8362 O O . HOH X 8 . ? -33.906 62.598 -28.056 1.00 54.61 ? 605 HOH H O 1 HETATM 8363 O O . HOH X 8 . ? -33.270 41.600 -36.912 1.00 50.47 ? 606 HOH H O 1 HETATM 8364 O O . HOH X 8 . ? -10.893 35.187 -33.602 1.00 46.19 ? 607 HOH H O 1 HETATM 8365 O O . HOH X 8 . ? -25.868 36.333 -52.917 1.00 55.04 ? 608 HOH H O 1 HETATM 8366 O O . HOH X 8 . ? -22.304 43.152 -48.266 1.00 55.68 ? 609 HOH H O 1 HETATM 8367 O O . HOH X 8 . ? -28.030 30.800 -56.081 1.00 56.54 ? 610 HOH H O 1 HETATM 8368 O O . HOH X 8 . ? -44.037 39.853 -64.571 1.00 58.24 ? 611 HOH H O 1 HETATM 8369 O O . HOH X 8 . ? -27.633 59.204 -44.638 1.00 57.50 ? 612 HOH H O 1 HETATM 8370 O O . HOH X 8 . ? -30.934 41.231 -50.429 1.00 60.07 ? 613 HOH H O 1 HETATM 8371 O O . HOH X 8 . ? -34.552 51.389 -39.522 1.00 54.31 ? 614 HOH H O 1 HETATM 8372 O O . HOH X 8 . ? -27.702 50.361 -45.872 1.00 52.46 ? 615 HOH H O 1 HETATM 8373 O O . HOH X 8 . ? -40.164 38.867 -41.018 1.00 57.36 ? 616 HOH H O 1 HETATM 8374 O O . HOH X 8 . ? -58.993 44.047 -49.556 1.00 61.10 ? 617 HOH H O 1 HETATM 8375 O O . HOH X 8 . ? -25.364 34.432 -56.607 1.00 64.78 ? 618 HOH H O 1 HETATM 8376 O O . HOH X 8 . ? -20.957 70.920 -27.762 1.00 56.47 ? 619 HOH H O 1 HETATM 8377 O O . HOH X 8 . ? -35.757 21.053 -42.137 1.00 54.09 ? 620 HOH H O 1 HETATM 8378 O O . HOH X 8 . ? -17.949 35.649 -27.112 1.00 35.06 ? 621 HOH H O 1 HETATM 8379 O O . HOH X 8 . ? -14.759 56.701 -45.140 1.00 53.83 ? 622 HOH H O 1 HETATM 8380 O O . HOH X 8 . ? -13.836 56.038 -42.929 1.00 45.15 ? 623 HOH H O 1 HETATM 8381 O O . HOH X 8 . ? -29.743 28.275 -39.397 1.00 44.56 ? 624 HOH H O 1 HETATM 8382 O O . HOH X 8 . ? -37.110 43.431 -48.817 1.00 56.02 ? 625 HOH H O 1 HETATM 8383 O O . HOH X 8 . ? -27.388 29.138 -37.945 1.00 47.62 ? 626 HOH H O 1 HETATM 8384 O O . HOH X 8 . ? -41.054 20.397 -48.774 1.00 57.21 ? 627 HOH H O 1 HETATM 8385 O O . HOH X 8 . ? -26.324 67.082 -27.338 1.00 57.97 ? 628 HOH H O 1 HETATM 8386 O O . HOH X 8 . ? -33.690 26.561 -56.040 1.00 51.70 ? 629 HOH H O 1 HETATM 8387 O O . HOH X 8 . ? -59.216 34.675 -61.032 1.00 62.73 ? 630 HOH H O 1 HETATM 8388 O O . HOH X 8 . ? -56.223 25.433 -51.969 1.00 53.50 ? 631 HOH H O 1 HETATM 8389 O O . HOH X 8 . ? -22.514 36.747 -20.625 1.00 52.05 ? 632 HOH H O 1 HETATM 8390 O O . HOH X 8 . ? -33.499 30.944 -34.919 1.00 57.96 ? 633 HOH H O 1 HETATM 8391 O O . HOH X 8 . ? -10.919 44.966 -18.823 1.00 46.64 ? 634 HOH H O 1 HETATM 8392 O O . HOH X 8 . ? -35.919 27.850 -36.428 1.00 55.75 ? 635 HOH H O 1 HETATM 8393 O O . HOH X 8 . ? -30.019 64.655 -21.692 1.00 55.69 ? 636 HOH H O 1 HETATM 8394 O O . HOH X 8 . ? -26.512 48.241 -47.582 1.00 68.66 ? 637 HOH H O 1 HETATM 8395 O O . HOH X 8 . ? -22.034 52.090 -45.830 1.00 65.47 ? 638 HOH H O 1 HETATM 8396 O O . HOH X 8 . ? -42.118 37.840 -44.632 1.00 55.11 ? 639 HOH H O 1 HETATM 8397 O O . HOH Y 8 . ? -37.511 51.948 -29.007 1.00 27.26 ? 301 HOH L O 1 HETATM 8398 O O . HOH Y 8 . ? -33.940 60.106 -24.880 1.00 31.90 ? 302 HOH L O 1 HETATM 8399 O O . HOH Y 8 . ? -43.590 56.070 -23.493 1.00 27.52 ? 303 HOH L O 1 HETATM 8400 O O . HOH Y 8 . ? -25.602 52.880 -19.795 1.00 25.43 ? 304 HOH L O 1 HETATM 8401 O O . HOH Y 8 . ? -25.382 58.131 -15.609 1.00 37.64 ? 305 HOH L O 1 HETATM 8402 O O . HOH Y 8 . ? -56.078 43.041 -19.499 1.00 35.34 ? 306 HOH L O 1 HETATM 8403 O O . HOH Y 8 . ? -18.968 44.748 -19.573 1.00 32.23 ? 307 HOH L O 1 HETATM 8404 O O . HOH Y 8 . ? -32.463 54.549 -10.923 1.00 33.40 ? 308 HOH L O 1 HETATM 8405 O O . HOH Y 8 . ? -53.859 44.280 -22.546 1.00 35.88 ? 309 HOH L O 1 HETATM 8406 O O . HOH Y 8 . ? -42.948 58.361 -11.647 1.00 40.70 ? 310 HOH L O 1 HETATM 8407 O O . HOH Y 8 . ? -35.459 54.618 -30.850 1.00 36.44 ? 311 HOH L O 1 HETATM 8408 O O . HOH Y 8 . ? -55.952 49.497 -11.674 1.00 25.42 ? 312 HOH L O 1 HETATM 8409 O O . HOH Y 8 . ? -19.764 42.298 -19.721 1.00 32.63 ? 313 HOH L O 1 HETATM 8410 O O . HOH Y 8 . ? -40.280 32.195 -36.124 1.00 41.78 ? 314 HOH L O 1 HETATM 8411 O O . HOH Y 8 . ? -35.285 40.314 -16.607 1.00 33.61 ? 315 HOH L O 1 HETATM 8412 O O . HOH Y 8 . ? -32.590 40.779 -15.222 1.00 33.15 ? 316 HOH L O 1 HETATM 8413 O O . HOH Y 8 . ? -56.212 41.675 -16.897 1.00 33.89 ? 317 HOH L O 1 HETATM 8414 O O . HOH Y 8 . ? -16.489 43.937 -19.146 1.00 31.31 ? 318 HOH L O 1 HETATM 8415 O O . HOH Y 8 . ? -46.975 43.670 -12.487 1.00 39.46 ? 319 HOH L O 1 HETATM 8416 O O . HOH Y 8 . ? -34.393 53.057 -34.033 1.00 40.96 ? 320 HOH L O 1 HETATM 8417 O O . HOH Y 8 . ? -34.656 41.597 -22.784 1.00 36.36 ? 321 HOH L O 1 HETATM 8418 O O . HOH Y 8 . ? -13.320 50.808 -14.030 1.00 39.63 ? 322 HOH L O 1 HETATM 8419 O O . HOH Y 8 . ? -45.341 35.169 -37.360 1.00 39.23 ? 323 HOH L O 1 HETATM 8420 O O . HOH Y 8 . ? -39.387 45.928 -27.065 1.00 36.66 ? 324 HOH L O 1 HETATM 8421 O O . HOH Y 8 . ? -19.695 42.224 -11.364 1.00 45.84 ? 325 HOH L O 1 HETATM 8422 O O . HOH Y 8 . ? -46.254 50.357 -27.364 1.00 43.70 ? 326 HOH L O 1 HETATM 8423 O O . HOH Y 8 . ? -35.248 43.276 -9.254 1.00 39.33 ? 327 HOH L O 1 HETATM 8424 O O . HOH Y 8 . ? -36.336 60.949 -11.467 1.00 38.96 ? 328 HOH L O 1 HETATM 8425 O O . HOH Y 8 . ? -32.729 62.519 -25.107 1.00 38.67 ? 329 HOH L O 1 HETATM 8426 O O . HOH Y 8 . ? -42.000 39.062 -13.715 1.00 40.07 ? 330 HOH L O 1 HETATM 8427 O O . HOH Y 8 . ? -40.962 56.856 -25.522 1.00 42.78 ? 331 HOH L O 1 HETATM 8428 O O . HOH Y 8 . ? -22.911 44.457 -20.850 1.00 20.09 ? 332 HOH L O 1 HETATM 8429 O O . HOH Y 8 . ? -21.098 56.372 -13.168 1.00 31.38 ? 333 HOH L O 1 HETATM 8430 O O . HOH Y 8 . ? -45.515 42.082 -19.261 1.00 32.40 ? 334 HOH L O 1 HETATM 8431 O O . HOH Y 8 . ? -24.590 43.202 -19.118 1.00 34.00 ? 335 HOH L O 1 HETATM 8432 O O . HOH Y 8 . ? -29.267 42.458 -20.883 1.00 28.25 ? 336 HOH L O 1 HETATM 8433 O O . HOH Y 8 . ? -36.484 44.054 -30.728 1.00 42.55 ? 337 HOH L O 1 HETATM 8434 O O . HOH Y 8 . ? -38.165 55.337 -8.447 1.00 45.44 ? 338 HOH L O 1 HETATM 8435 O O . HOH Y 8 . ? -22.707 53.931 -14.133 1.00 34.47 ? 339 HOH L O 1 HETATM 8436 O O . HOH Y 8 . ? -43.436 45.628 -26.263 1.00 40.86 ? 340 HOH L O 1 HETATM 8437 O O . HOH Y 8 . ? -36.758 45.989 -36.938 1.00 48.23 ? 341 HOH L O 1 HETATM 8438 O O . HOH Y 8 . ? -32.656 38.740 -20.651 1.00 39.88 ? 342 HOH L O 1 HETATM 8439 O O . HOH Y 8 . ? -49.958 43.751 -24.812 1.00 42.91 ? 343 HOH L O 1 HETATM 8440 O O . HOH Y 8 . ? -44.981 32.203 -43.352 1.00 36.91 ? 344 HOH L O 1 HETATM 8441 O O . HOH Y 8 . ? -43.460 41.701 -11.505 1.00 48.81 ? 345 HOH L O 1 HETATM 8442 O O . HOH Y 8 . ? -53.035 56.026 -22.251 1.00 45.95 ? 346 HOH L O 1 HETATM 8443 O O . HOH Y 8 . ? -42.010 24.839 -34.704 1.00 55.41 ? 347 HOH L O 1 HETATM 8444 O O . HOH Y 8 . ? -38.243 40.466 -20.311 1.00 43.59 ? 348 HOH L O 1 HETATM 8445 O O . HOH Y 8 . ? -23.953 42.657 -10.050 1.00 46.17 ? 349 HOH L O 1 HETATM 8446 O O . HOH Y 8 . ? -39.272 57.445 -8.014 1.00 54.00 ? 350 HOH L O 1 HETATM 8447 O O . HOH Y 8 . ? -40.668 45.727 -9.998 1.00 42.72 ? 351 HOH L O 1 HETATM 8448 O O . HOH Y 8 . ? -28.350 62.509 -9.468 1.00 51.03 ? 352 HOH L O 1 HETATM 8449 O O . HOH Y 8 . ? -45.557 33.689 -39.921 1.00 38.17 ? 353 HOH L O 1 HETATM 8450 O O . HOH Y 8 . ? -47.906 48.327 -28.090 1.00 59.75 ? 354 HOH L O 1 HETATM 8451 O O . HOH Y 8 . ? -38.612 62.760 -13.501 1.00 44.31 ? 355 HOH L O 1 HETATM 8452 O O . HOH Y 8 . ? -43.205 61.246 -12.004 1.00 50.10 ? 356 HOH L O 1 HETATM 8453 O O . HOH Y 8 . ? -35.393 58.794 -29.326 1.00 59.99 ? 357 HOH L O 1 HETATM 8454 O O . HOH Y 8 . ? -52.972 23.319 -56.895 1.00 52.06 ? 358 HOH L O 1 HETATM 8455 O O . HOH Y 8 . ? -49.709 60.243 -16.733 1.00 48.63 ? 359 HOH L O 1 HETATM 8456 O O . HOH Y 8 . ? -21.993 43.304 -3.547 1.00 53.51 ? 360 HOH L O 1 HETATM 8457 O O . HOH Y 8 . ? -42.773 35.445 -36.716 1.00 45.23 ? 361 HOH L O 1 HETATM 8458 O O . HOH Y 8 . ? -36.453 44.531 -25.996 1.00 44.86 ? 362 HOH L O 1 HETATM 8459 O O . HOH Y 8 . ? -46.106 62.694 -18.020 1.00 48.97 ? 363 HOH L O 1 HETATM 8460 O O . HOH Y 8 . ? -27.689 60.635 -7.556 1.00 57.67 ? 364 HOH L O 1 HETATM 8461 O O . HOH Y 8 . ? -40.670 47.306 -7.985 1.00 45.39 ? 365 HOH L O 1 HETATM 8462 O O . HOH Y 8 . ? -41.979 57.602 -7.418 1.00 55.05 ? 366 HOH L O 1 HETATM 8463 O O . HOH Y 8 . ? -47.037 41.324 -14.393 1.00 50.53 ? 367 HOH L O 1 HETATM 8464 O O . HOH Y 8 . ? -23.404 37.237 -14.623 1.00 64.18 ? 368 HOH L O 1 HETATM 8465 O O . HOH Y 8 . ? -61.190 30.960 -38.745 1.00 61.71 ? 369 HOH L O 1 HETATM 8466 O O . HOH Y 8 . ? -30.614 47.326 -1.634 1.00 59.96 ? 370 HOH L O 1 HETATM 8467 O O . HOH Y 8 . ? -36.134 66.908 -17.298 1.00 54.72 ? 371 HOH L O 1 HETATM 8468 O O . HOH Y 8 . ? -46.874 61.672 -23.069 1.00 54.26 ? 372 HOH L O 1 HETATM 8469 O O . HOH Y 8 . ? -36.367 60.962 -8.058 1.00 53.40 ? 373 HOH L O 1 HETATM 8470 O O . HOH Y 8 . ? -29.350 66.599 -15.129 1.00 48.50 ? 374 HOH L O 1 HETATM 8471 O O . HOH Y 8 . ? -47.391 46.026 -27.964 1.00 56.79 ? 375 HOH L O 1 HETATM 8472 O O . HOH Y 8 . ? -33.920 60.518 -6.263 1.00 60.54 ? 376 HOH L O 1 HETATM 8473 O O . HOH Y 8 . ? -23.642 60.564 -13.292 1.00 51.47 ? 377 HOH L O 1 HETATM 8474 O O . HOH Y 8 . ? -43.179 20.366 -47.260 1.00 55.33 ? 378 HOH L O 1 HETATM 8475 O O . HOH Y 8 . ? -59.805 39.391 -34.518 1.00 59.15 ? 379 HOH L O 1 HETATM 8476 O O . HOH Y 8 . ? -22.311 59.053 -15.123 1.00 50.04 ? 380 HOH L O 1 HETATM 8477 O O . HOH Y 8 . ? -49.406 62.300 -22.388 1.00 53.88 ? 381 HOH L O 1 HETATM 8478 O O . HOH Y 8 . ? -47.258 40.961 -17.473 1.00 45.94 ? 382 HOH L O 1 HETATM 8479 O O . HOH Y 8 . ? -28.302 46.762 -0.578 1.00 56.45 ? 383 HOH L O 1 HETATM 8480 O O . HOH Y 8 . ? -21.641 40.872 -18.624 1.00 50.97 ? 384 HOH L O 1 HETATM 8481 O O . HOH Y 8 . ? -36.456 54.846 -33.727 1.00 47.67 ? 385 HOH L O 1 HETATM 8482 O O . HOH Y 8 . ? -12.745 49.737 -19.678 1.00 48.58 ? 386 HOH L O 1 HETATM 8483 O O . HOH Y 8 . ? -44.300 57.613 -9.321 1.00 52.22 ? 387 HOH L O 1 HETATM 8484 O O . HOH Y 8 . ? -48.094 23.516 -52.336 1.00 47.07 ? 388 HOH L O 1 HETATM 8485 O O . HOH Y 8 . ? -44.468 39.753 -20.452 1.00 41.72 ? 389 HOH L O 1 HETATM 8486 O O . HOH Y 8 . ? -21.454 57.601 -9.799 1.00 60.27 ? 390 HOH L O 1 HETATM 8487 O O . HOH Y 8 . ? -58.077 43.156 -21.001 1.00 45.39 ? 391 HOH L O 1 HETATM 8488 O O . HOH Y 8 . ? -57.822 52.596 -17.118 1.00 47.73 ? 392 HOH L O 1 HETATM 8489 O O . HOH Y 8 . ? -41.144 58.115 -23.651 1.00 51.24 ? 393 HOH L O 1 HETATM 8490 O O . HOH Y 8 . ? -55.920 52.436 -13.507 1.00 45.26 ? 394 HOH L O 1 HETATM 8491 O O . HOH Y 8 . ? -45.772 52.861 -28.273 1.00 44.92 ? 395 HOH L O 1 HETATM 8492 O O . HOH Y 8 . ? -34.009 65.482 -24.098 1.00 49.25 ? 396 HOH L O 1 HETATM 8493 O O . HOH Y 8 . ? -36.695 43.883 -28.305 1.00 52.66 ? 397 HOH L O 1 HETATM 8494 O O . HOH Y 8 . ? -44.712 55.498 -28.712 1.00 51.20 ? 398 HOH L O 1 HETATM 8495 O O . HOH Y 8 . ? -38.409 32.834 -34.496 1.00 48.98 ? 399 HOH L O 1 HETATM 8496 O O . HOH Y 8 . ? -60.302 48.369 -21.212 1.00 51.61 ? 400 HOH L O 1 HETATM 8497 O O . HOH Y 8 . ? -42.154 36.777 -14.705 1.00 53.74 ? 401 HOH L O 1 HETATM 8498 O O . HOH Y 8 . ? -35.357 38.213 -12.984 1.00 48.98 ? 402 HOH L O 1 HETATM 8499 O O . HOH Y 8 . ? -31.395 38.435 -14.495 1.00 54.30 ? 403 HOH L O 1 HETATM 8500 O O . HOH Y 8 . ? -54.236 39.754 -16.840 1.00 55.05 ? 404 HOH L O 1 HETATM 8501 O O . HOH Y 8 . ? -22.022 49.133 -2.057 1.00 62.71 ? 405 HOH L O 1 HETATM 8502 O O . HOH Y 8 . ? -54.099 60.465 -21.782 1.00 62.50 ? 406 HOH L O 1 HETATM 8503 O O . HOH Y 8 . ? -28.784 40.047 -20.416 1.00 54.84 ? 407 HOH L O 1 HETATM 8504 O O . HOH Y 8 . ? -37.553 62.987 -9.558 1.00 55.20 ? 408 HOH L O 1 HETATM 8505 O O . HOH Y 8 . ? -55.912 49.281 -22.119 1.00 50.48 ? 409 HOH L O 1 HETATM 8506 O O . HOH Y 8 . ? -22.899 46.590 0.262 1.00 64.56 ? 410 HOH L O 1 HETATM 8507 O O . HOH Y 8 . ? -54.999 53.384 -11.106 1.00 36.06 ? 411 HOH L O 1 HETATM 8508 O O . HOH Y 8 . ? -32.792 56.724 -28.822 1.00 38.39 ? 412 HOH L O 1 HETATM 8509 O O . HOH Y 8 . ? -50.202 40.667 -15.028 1.00 58.32 ? 413 HOH L O 1 HETATM 8510 O O . HOH Y 8 . ? -49.632 39.859 -26.169 1.00 49.50 ? 414 HOH L O 1 HETATM 8511 O O . HOH Y 8 . ? -45.668 48.095 -10.036 1.00 47.39 ? 415 HOH L O 1 HETATM 8512 O O . HOH Y 8 . ? -41.314 44.285 -26.067 1.00 48.12 ? 416 HOH L O 1 HETATM 8513 O O . HOH Y 8 . ? -34.536 65.495 -13.863 1.00 45.95 ? 417 HOH L O 1 HETATM 8514 O O . HOH Y 8 . ? -42.286 48.655 -32.364 1.00 46.18 ? 418 HOH L O 1 HETATM 8515 O O . HOH Y 8 . ? -60.760 37.997 -32.927 1.00 61.26 ? 419 HOH L O 1 HETATM 8516 O O . HOH Y 8 . ? -59.223 41.439 -19.801 1.00 57.97 ? 420 HOH L O 1 HETATM 8517 O O . HOH Y 8 . ? -32.407 66.533 -22.702 1.00 57.20 ? 421 HOH L O 1 HETATM 8518 O O . HOH Y 8 . ? -24.348 57.214 -7.773 1.00 56.61 ? 422 HOH L O 1 HETATM 8519 O O . HOH Y 8 . ? -54.384 41.736 -21.095 1.00 61.77 ? 423 HOH L O 1 HETATM 8520 O O . HOH Y 8 . ? -34.571 47.546 -6.070 1.00 58.44 ? 424 HOH L O 1 HETATM 8521 O O . HOH Y 8 . ? -46.888 25.285 -31.156 1.00 58.56 ? 425 HOH L O 1 HETATM 8522 O O . HOH Y 8 . ? -23.148 41.242 -16.808 1.00 56.38 ? 426 HOH L O 1 HETATM 8523 O O . HOH Y 8 . ? -35.972 59.895 -26.836 1.00 55.89 ? 427 HOH L O 1 HETATM 8524 O O . HOH Y 8 . ? -10.656 50.571 -18.422 1.00 66.70 ? 428 HOH L O 1 HETATM 8525 O O . HOH Y 8 . ? -57.103 43.240 -28.806 1.00 55.21 ? 429 HOH L O 1 HETATM 8526 O O . HOH Y 8 . ? -58.383 50.228 -20.251 1.00 48.36 ? 430 HOH L O 1 HETATM 8527 O O . HOH Y 8 . ? -61.213 32.439 -41.168 1.00 65.40 ? 431 HOH L O 1 HETATM 8528 O O . HOH Y 8 . ? -52.670 56.993 -24.621 1.00 60.03 ? 432 HOH L O 1 HETATM 8529 O O . HOH Y 8 . ? -51.880 40.127 -22.289 1.00 61.33 ? 433 HOH L O 1 HETATM 8530 O O . HOH Y 8 . ? -45.034 50.426 -30.154 1.00 56.47 ? 434 HOH L O 1 HETATM 8531 O O . HOH Y 8 . ? -46.808 27.650 -31.151 1.00 57.00 ? 435 HOH L O 1 HETATM 8532 O O . HOH Y 8 . ? -49.855 40.889 -18.167 1.00 51.25 ? 436 HOH L O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ALA 1 7 ? ? ? A . n A 1 2 ASP 2 8 8 ASP ASP A . n A 1 3 PRO 3 9 9 PRO PRO A . n A 1 4 GLY 4 10 10 GLY GLY A . n A 1 5 ASP 5 11 11 ASP ASP A . n A 1 6 GLN 6 12 12 GLN GLN A . n A 1 7 ILE 7 13 13 ILE ILE A . n A 1 8 CYS 8 14 14 CYS CYS A . n A 1 9 ILE 9 15 15 ILE ILE A . n A 1 10 GLY 10 16 16 GLY GLY A . n A 1 11 TYR 11 17 17 TYR TYR A . n A 1 12 HIS 12 18 18 HIS HIS A . n A 1 13 ALA 13 19 19 ALA ALA A . n A 1 14 ASN 14 20 20 ASN ASN A . n A 1 15 ASN 15 21 21 ASN ASN A . n A 1 16 SER 16 22 22 SER SER A . n A 1 17 THR 17 23 23 THR THR A . n A 1 18 GLU 18 24 24 GLU GLU A . n A 1 19 GLN 19 25 25 GLN GLN A . n A 1 20 VAL 20 26 26 VAL VAL A . n A 1 21 ASP 21 27 27 ASP ASP A . n A 1 22 THR 22 28 28 THR THR A . n A 1 23 ILE 23 29 29 ILE ILE A . n A 1 24 MET 24 30 30 MET MET A . n A 1 25 GLU 25 31 31 GLU GLU A . n A 1 26 LYS 26 32 32 LYS LYS A . n A 1 27 ASN 27 33 33 ASN ASN A . n A 1 28 VAL 28 34 34 VAL VAL A . n A 1 29 THR 29 35 35 THR THR A . n A 1 30 VAL 30 36 36 VAL VAL A . n A 1 31 THR 31 37 37 THR THR A . n A 1 32 HIS 32 38 38 HIS HIS A . n A 1 33 ALA 33 39 39 ALA ALA A . n A 1 34 GLN 34 40 40 GLN GLN A . n A 1 35 ASP 35 41 41 ASP ASP A . n A 1 36 ILE 36 42 42 ILE ILE A . n A 1 37 LEU 37 43 43 LEU LEU A . n A 1 38 GLU 38 44 44 GLU GLU A . n A 1 39 LYS 39 45 45 LYS LYS A . n A 1 40 LYS 40 46 46 LYS LYS A . n A 1 41 HIS 41 47 47 HIS HIS A . n A 1 42 ASN 42 48 48 ASN ASN A . n A 1 43 GLY 43 49 49 GLY GLY A . n A 1 44 LYS 44 50 50 LYS LYS A . n A 1 45 LEU 45 51 51 LEU LEU A . n A 1 46 CYS 46 52 52 CYS CYS A . n A 1 47 ASP 47 53 53 ASP ASP A . n A 1 48 LEU 48 54 54 LEU LEU A . n A 1 49 ASP 49 55 55 ASP ASP A . n A 1 50 GLY 50 55 55 GLY GLY A A n A 1 51 VAL 51 56 56 VAL VAL A . n A 1 52 LYS 52 57 57 LYS LYS A . n A 1 53 PRO 53 58 58 PRO PRO A . n A 1 54 LEU 54 59 59 LEU LEU A . n A 1 55 ILE 55 60 60 ILE ILE A . n A 1 56 LEU 56 61 61 LEU LEU A . n A 1 57 ARG 57 62 62 ARG ARG A . n A 1 58 ASP 58 63 63 ASP ASP A . n A 1 59 CYS 59 64 64 CYS CYS A . n A 1 60 SER 60 65 65 SER SER A . n A 1 61 VAL 61 66 66 VAL VAL A . n A 1 62 ALA 62 67 67 ALA ALA A . n A 1 63 GLY 63 68 68 GLY GLY A . n A 1 64 TRP 64 69 69 TRP TRP A . n A 1 65 LEU 65 70 70 LEU LEU A . n A 1 66 LEU 66 71 71 LEU LEU A . n A 1 67 GLY 67 72 72 GLY GLY A . n A 1 68 ASN 68 73 73 ASN ASN A . n A 1 69 PRO 69 74 74 PRO PRO A . n A 1 70 MET 70 75 75 MET MET A . n A 1 71 CYS 71 76 76 CYS CYS A . n A 1 72 ASP 72 77 77 ASP ASP A . n A 1 73 GLU 73 78 78 GLU GLU A . n A 1 74 PHE 74 79 79 PHE PHE A . n A 1 75 ILE 75 80 80 ILE ILE A . n A 1 76 ASN 76 81 81 ASN ASN A . n A 1 77 VAL 77 82 82 VAL VAL A . n A 1 78 PRO 78 83 83 PRO PRO A . n A 1 79 GLU 79 83 83 GLU GLU A A n A 1 80 TRP 80 84 84 TRP TRP A . n A 1 81 SER 81 85 85 SER SER A . n A 1 82 TYR 82 86 86 TYR TYR A . n A 1 83 ILE 83 87 87 ILE ILE A . n A 1 84 VAL 84 88 88 VAL VAL A . n A 1 85 GLU 85 89 89 GLU GLU A . n A 1 86 LYS 86 90 90 LYS LYS A . n A 1 87 ALA 87 91 91 ALA ALA A . n A 1 88 ASN 88 92 92 ASN ASN A . n A 1 89 PRO 89 93 93 PRO PRO A . n A 1 90 VAL 90 94 94 VAL VAL A . n A 1 91 ASN 91 95 95 ASN ASN A . n A 1 92 ASP 92 96 96 ASP ASP A . n A 1 93 LEU 93 96 96 LEU LEU A A n A 1 94 CYS 94 97 97 CYS CYS A . n A 1 95 TYR 95 98 98 TYR TYR A . n A 1 96 PRO 96 99 99 PRO PRO A . n A 1 97 GLY 97 100 100 GLY GLY A . n A 1 98 ASP 98 101 101 ASP ASP A . n A 1 99 PHE 99 102 102 PHE PHE A . n A 1 100 ASN 100 103 103 ASN ASN A . n A 1 101 ASP 101 104 104 ASP ASP A . n A 1 102 TYR 102 105 105 TYR TYR A . n A 1 103 GLU 103 106 106 GLU GLU A . n A 1 104 GLU 104 107 107 GLU GLU A . n A 1 105 LEU 105 108 108 LEU LEU A . n A 1 106 LYS 106 109 109 LYS LYS A . n A 1 107 HIS 107 110 110 HIS HIS A . n A 1 108 LEU 108 111 111 LEU LEU A . n A 1 109 LEU 109 112 112 LEU LEU A . n A 1 110 SER 110 113 113 SER SER A . n A 1 111 ARG 111 114 114 ARG ARG A . n A 1 112 ILE 112 115 115 ILE ILE A . n A 1 113 ASN 113 116 116 ASN ASN A . n A 1 114 HIS 114 117 117 HIS HIS A . n A 1 115 PHE 115 118 118 PHE PHE A . n A 1 116 GLU 116 119 119 GLU GLU A . n A 1 117 LYS 117 120 120 LYS LYS A . n A 1 118 ILE 118 121 121 ILE ILE A . n A 1 119 GLN 119 122 122 GLN GLN A . n A 1 120 ILE 120 123 123 ILE ILE A . n A 1 121 ILE 121 124 124 ILE ILE A . n A 1 122 PRO 122 125 125 PRO PRO A . n A 1 123 LYS 123 125 125 LYS LYS A A n A 1 124 SER 124 125 125 SER SER A B n A 1 125 SER 125 126 126 SER SER A . n A 1 126 TRP 126 127 127 TRP TRP A . n A 1 127 SER 127 128 128 SER SER A . n A 1 128 SER 128 129 129 SER SER A . n A 1 129 HIS 129 130 130 HIS HIS A . n A 1 130 GLU 130 131 131 GLU GLU A . n A 1 131 ALA 131 132 132 ALA ALA A . n A 1 132 SER 132 133 133 SER SER A . n A 1 133 LEU 133 133 133 LEU LEU A A n A 1 134 GLY 134 134 134 GLY GLY A . n A 1 135 VAL 135 135 135 VAL VAL A . n A 1 136 SER 136 136 136 SER SER A . n A 1 137 SER 137 137 137 SER SER A . n A 1 138 ALA 138 138 138 ALA ALA A . n A 1 139 CYS 139 139 139 CYS CYS A . n A 1 140 PRO 140 140 140 PRO PRO A . n A 1 141 TYR 141 141 141 TYR TYR A . n A 1 142 GLN 142 142 142 GLN GLN A . n A 1 143 GLY 143 143 143 GLY GLY A . n A 1 144 LYS 144 144 144 LYS LYS A . n A 1 145 SER 145 145 145 SER SER A . n A 1 146 SER 146 146 146 SER SER A . n A 1 147 PHE 147 147 147 PHE PHE A . n A 1 148 PHE 148 148 148 PHE PHE A . n A 1 149 ARG 149 149 149 ARG ARG A . n A 1 150 ASN 150 150 150 ASN ASN A . n A 1 151 VAL 151 151 151 VAL VAL A . n A 1 152 VAL 152 152 152 VAL VAL A . n A 1 153 TRP 153 153 153 TRP TRP A . n A 1 154 LEU 154 154 154 LEU LEU A . n A 1 155 ILE 155 155 155 ILE ILE A . n A 1 156 LYS 156 156 156 LYS LYS A . n A 1 157 LYS 157 157 157 LYS LYS A . n A 1 158 ASN 158 158 158 ASN ASN A . n A 1 159 SER 159 159 159 SER SER A . n A 1 160 THR 160 160 160 THR THR A . n A 1 161 TYR 161 161 161 TYR TYR A . n A 1 162 PRO 162 162 162 PRO PRO A . n A 1 163 THR 163 163 163 THR THR A . n A 1 164 ILE 164 164 164 ILE ILE A . n A 1 165 LYS 165 165 165 LYS LYS A . n A 1 166 ARG 166 166 166 ARG ARG A . n A 1 167 SER 167 167 167 SER SER A . n A 1 168 TYR 168 168 168 TYR TYR A . n A 1 169 ASN 169 169 169 ASN ASN A . n A 1 170 ASN 170 170 170 ASN ASN A . n A 1 171 THR 171 171 171 THR THR A . n A 1 172 ASN 172 172 172 ASN ASN A . n A 1 173 GLN 173 173 173 GLN GLN A . n A 1 174 GLU 174 174 174 GLU GLU A . n A 1 175 ASP 175 175 175 ASP ASP A . n A 1 176 LEU 176 176 176 LEU LEU A . n A 1 177 LEU 177 177 177 LEU LEU A . n A 1 178 VAL 178 178 178 VAL VAL A . n A 1 179 LEU 179 179 179 LEU LEU A . n A 1 180 TRP 180 180 180 TRP TRP A . n A 1 181 GLY 181 181 181 GLY GLY A . n A 1 182 ILE 182 182 182 ILE ILE A . n A 1 183 HIS 183 183 183 HIS HIS A . n A 1 184 HIS 184 184 184 HIS HIS A . n A 1 185 PRO 185 185 185 PRO PRO A . n A 1 186 ASN 186 186 186 ASN ASN A . n A 1 187 ASP 187 187 187 ASP ASP A . n A 1 188 ALA 188 188 188 ALA ALA A . n A 1 189 ALA 189 189 189 ALA ALA A . n A 1 190 GLU 190 190 190 GLU GLU A . n A 1 191 GLN 191 191 191 GLN GLN A . n A 1 192 THR 192 192 192 THR THR A . n A 1 193 LYS 193 193 193 LYS LYS A . n A 1 194 LEU 194 194 194 LEU LEU A . n A 1 195 TYR 195 195 195 TYR TYR A . n A 1 196 GLN 196 196 196 GLN GLN A . n A 1 197 ASN 197 197 197 ASN ASN A . n A 1 198 PRO 198 198 198 PRO PRO A . n A 1 199 THR 199 199 199 THR THR A . n A 1 200 THR 200 200 200 THR THR A . n A 1 201 TYR 201 201 201 TYR TYR A . n A 1 202 ILE 202 202 202 ILE ILE A . n A 1 203 SER 203 203 203 SER SER A . n A 1 204 VAL 204 204 204 VAL VAL A . n A 1 205 GLY 205 205 205 GLY GLY A . n A 1 206 THR 206 206 206 THR THR A . n A 1 207 SER 207 207 207 SER SER A . n A 1 208 THR 208 208 208 THR THR A . n A 1 209 LEU 209 209 209 LEU LEU A . n A 1 210 ASN 210 210 210 ASN ASN A . n A 1 211 GLN 211 211 211 GLN GLN A . n A 1 212 ARG 212 212 212 ARG ARG A . n A 1 213 LEU 213 213 213 LEU LEU A . n A 1 214 VAL 214 214 214 VAL VAL A . n A 1 215 PRO 215 215 215 PRO PRO A . n A 1 216 ARG 216 216 216 ARG ARG A . n A 1 217 ILE 217 217 217 ILE ILE A . n A 1 218 ALA 218 218 218 ALA ALA A . n A 1 219 THR 219 219 219 THR THR A . n A 1 220 ARG 220 220 220 ARG ARG A . n A 1 221 SER 221 221 221 SER SER A . n A 1 222 LYS 222 222 222 LYS LYS A . n A 1 223 VAL 223 223 223 VAL VAL A . n A 1 224 ASN 224 224 224 ASN ASN A . n A 1 225 GLY 225 225 225 GLY GLY A . n A 1 226 GLN 226 226 226 GLN GLN A . n A 1 227 SER 227 227 227 SER SER A . n A 1 228 GLY 228 228 228 GLY GLY A . n A 1 229 ARG 229 229 229 ARG ARG A . n A 1 230 MET 230 230 230 MET MET A . n A 1 231 GLU 231 231 231 GLU GLU A . n A 1 232 PHE 232 232 232 PHE PHE A . n A 1 233 PHE 233 233 233 PHE PHE A . n A 1 234 TRP 234 234 234 TRP TRP A . n A 1 235 THR 235 235 235 THR THR A . n A 1 236 ILE 236 236 236 ILE ILE A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 LYS 238 238 238 LYS LYS A . n A 1 239 PRO 239 239 239 PRO PRO A . n A 1 240 ASN 240 240 240 ASN ASN A . n A 1 241 ASP 241 241 241 ASP ASP A . n A 1 242 ALA 242 242 242 ALA ALA A . n A 1 243 ILE 243 243 243 ILE ILE A . n A 1 244 ASN 244 244 244 ASN ASN A . n A 1 245 PHE 245 245 245 PHE PHE A . n A 1 246 GLU 246 246 246 GLU GLU A . n A 1 247 SER 247 247 247 SER SER A . n A 1 248 ASN 248 248 248 ASN ASN A . n A 1 249 GLY 249 249 249 GLY GLY A . n A 1 250 ASN 250 250 250 ASN ASN A . n A 1 251 PHE 251 251 251 PHE PHE A . n A 1 252 ILE 252 252 252 ILE ILE A . n A 1 253 ALA 253 253 253 ALA ALA A . n A 1 254 PRO 254 254 254 PRO PRO A . n A 1 255 GLU 255 255 255 GLU GLU A . n A 1 256 TYR 256 256 256 TYR TYR A . n A 1 257 ALA 257 257 257 ALA ALA A . n A 1 258 TYR 258 258 258 TYR TYR A . n A 1 259 LYS 259 259 259 LYS LYS A . n A 1 260 ILE 260 260 260 ILE ILE A . n A 1 261 VAL 261 260 260 VAL VAL A A n A 1 262 LYS 262 261 261 LYS LYS A . n A 1 263 LYS 263 262 262 LYS LYS A . n A 1 264 GLY 264 263 263 GLY GLY A . n A 1 265 ASP 265 264 264 ASP ASP A . n A 1 266 SER 266 265 265 SER SER A . n A 1 267 THR 267 266 266 THR THR A . n A 1 268 ILE 268 267 267 ILE ILE A . n A 1 269 MET 269 268 268 MET MET A . n A 1 270 LYS 270 269 269 LYS LYS A . n A 1 271 SER 271 270 270 SER SER A . n A 1 272 GLU 272 271 271 GLU GLU A . n A 1 273 LEU 273 272 272 LEU LEU A . n A 1 274 GLU 274 273 273 GLU GLU A . n A 1 275 TYR 275 274 274 TYR TYR A . n A 1 276 GLY 276 275 275 GLY GLY A . n A 1 277 ASN 277 276 276 ASN ASN A . n A 1 278 CYS 278 277 277 CYS CYS A . n A 1 279 ASN 279 278 278 ASN ASN A . n A 1 280 THR 280 279 279 THR THR A . n A 1 281 LYS 281 280 280 LYS LYS A . n A 1 282 CYS 282 281 281 CYS CYS A . n A 1 283 GLN 283 282 282 GLN GLN A . n A 1 284 THR 284 283 283 THR THR A . n A 1 285 PRO 285 284 284 PRO PRO A . n A 1 286 MET 286 285 285 MET MET A . n A 1 287 GLY 287 286 286 GLY GLY A . n A 1 288 ALA 288 287 287 ALA ALA A . n A 1 289 ILE 289 288 288 ILE ILE A . n A 1 290 ASN 290 289 289 ASN ASN A . n A 1 291 SER 291 290 290 SER SER A . n A 1 292 SER 292 291 291 SER SER A . n A 1 293 MET 293 292 292 MET MET A . n A 1 294 PRO 294 293 293 PRO PRO A . n A 1 295 PHE 295 294 294 PHE PHE A . n A 1 296 HIS 296 295 295 HIS HIS A . n A 1 297 ASN 297 296 296 ASN ASN A . n A 1 298 ILE 298 297 297 ILE ILE A . n A 1 299 HIS 299 298 298 HIS HIS A . n A 1 300 PRO 300 299 299 PRO PRO A . n A 1 301 LEU 301 300 300 LEU LEU A . n A 1 302 THR 302 301 301 THR THR A . n A 1 303 ILE 303 302 302 ILE ILE A . n A 1 304 GLY 304 303 303 GLY GLY A . n A 1 305 GLU 305 304 304 GLU GLU A . n A 1 306 CYS 306 305 305 CYS CYS A . n A 1 307 PRO 307 306 306 PRO PRO A . n A 1 308 LYS 308 307 307 LYS LYS A . n A 1 309 TYR 309 308 308 TYR TYR A . n A 1 310 VAL 310 309 309 VAL VAL A . n A 1 311 LYS 311 310 310 LYS LYS A . n A 1 312 SER 312 311 311 SER SER A . n A 1 313 ASN 313 312 312 ASN ASN A . n A 1 314 ARG 314 313 313 ARG ARG A . n A 1 315 LEU 315 314 314 LEU LEU A . n A 1 316 VAL 316 315 315 VAL VAL A . n A 1 317 LEU 317 316 316 LEU LEU A . n A 1 318 ALA 318 317 317 ALA ALA A . n A 1 319 THR 319 318 318 THR THR A . n A 1 320 GLY 320 319 319 GLY GLY A . n A 1 321 LEU 321 320 320 LEU LEU A . n A 1 322 ARG 322 321 321 ARG ARG A . n A 1 323 ASN 323 322 322 ASN ASN A . n A 1 324 SER 324 323 323 SER SER A . n A 1 325 PRO 325 324 324 PRO PRO A . n A 1 326 GLN 326 325 ? ? ? A . n A 1 327 ARG 327 326 ? ? ? A . n A 1 328 GLU 328 327 ? ? ? A . n A 1 329 ARG 329 328 ? ? ? A . n A 1 330 ARG 330 329 ? ? ? A . n A 1 331 ARG 331 330 ? ? ? A . n A 1 332 LYS 332 331 ? ? ? A . n A 1 333 LYS 333 332 ? ? ? A . n A 1 334 ARG 334 333 ? ? ? A . n B 2 1 GLY 1 1 1 GLY GLY B . n B 2 2 LEU 2 2 2 LEU LEU B . n B 2 3 PHE 3 3 3 PHE PHE B . n B 2 4 GLY 4 4 4 GLY GLY B . n B 2 5 ALA 5 5 5 ALA ALA B . n B 2 6 ILE 6 6 6 ILE ILE B . n B 2 7 ALA 7 7 7 ALA ALA B . n B 2 8 GLY 8 8 8 GLY GLY B . n B 2 9 PHE 9 9 9 PHE PHE B . n B 2 10 ILE 10 10 10 ILE ILE B . n B 2 11 GLU 11 11 11 GLU GLU B . n B 2 12 GLY 12 12 12 GLY GLY B . n B 2 13 GLY 13 13 13 GLY GLY B . n B 2 14 TRP 14 14 14 TRP TRP B . n B 2 15 GLN 15 15 15 GLN GLN B . n B 2 16 GLY 16 16 16 GLY GLY B . n B 2 17 MET 17 17 17 MET MET B . n B 2 18 VAL 18 18 18 VAL VAL B . n B 2 19 ASP 19 19 19 ASP ASP B . n B 2 20 GLY 20 20 20 GLY GLY B . n B 2 21 TRP 21 21 21 TRP TRP B . n B 2 22 TYR 22 22 22 TYR TYR B . n B 2 23 GLY 23 23 23 GLY GLY B . n B 2 24 TYR 24 24 24 TYR TYR B . n B 2 25 HIS 25 25 25 HIS HIS B . n B 2 26 HIS 26 26 26 HIS HIS B . n B 2 27 SER 27 27 27 SER SER B . n B 2 28 ASN 28 28 28 ASN ASN B . n B 2 29 GLU 29 29 29 GLU GLU B . n B 2 30 GLN 30 30 30 GLN GLN B . n B 2 31 GLY 31 31 31 GLY GLY B . n B 2 32 SER 32 32 32 SER SER B . n B 2 33 GLY 33 33 33 GLY GLY B . n B 2 34 TYR 34 34 34 TYR TYR B . n B 2 35 ALA 35 35 35 ALA ALA B . n B 2 36 ALA 36 36 36 ALA ALA B . n B 2 37 ASP 37 37 37 ASP ASP B . n B 2 38 LYS 38 38 38 LYS LYS B . n B 2 39 GLU 39 39 39 GLU GLU B . n B 2 40 SER 40 40 40 SER SER B . n B 2 41 THR 41 41 41 THR THR B . n B 2 42 GLN 42 42 42 GLN GLN B . n B 2 43 LYS 43 43 43 LYS LYS B . n B 2 44 ALA 44 44 44 ALA ALA B . n B 2 45 ILE 45 45 45 ILE ILE B . n B 2 46 ASP 46 46 46 ASP ASP B . n B 2 47 GLY 47 47 47 GLY GLY B . n B 2 48 VAL 48 48 48 VAL VAL B . n B 2 49 THR 49 49 49 THR THR B . n B 2 50 ASN 50 50 50 ASN ASN B . n B 2 51 LYS 51 51 51 LYS LYS B . n B 2 52 VAL 52 52 52 VAL VAL B . n B 2 53 ASN 53 53 53 ASN ASN B . n B 2 54 SER 54 54 54 SER SER B . n B 2 55 ILE 55 55 55 ILE ILE B . n B 2 56 ILE 56 56 56 ILE ILE B . n B 2 57 ASP 57 57 57 ASP ASP B . n B 2 58 LYS 58 58 58 LYS LYS B . n B 2 59 MET 59 59 59 MET MET B . n B 2 60 ASN 60 60 60 ASN ASN B . n B 2 61 THR 61 61 61 THR THR B . n B 2 62 GLN 62 62 62 GLN GLN B . n B 2 63 PHE 63 63 63 PHE PHE B . n B 2 64 GLU 64 64 64 GLU GLU B . n B 2 65 ALA 65 65 65 ALA ALA B . n B 2 66 VAL 66 66 66 VAL VAL B . n B 2 67 GLY 67 67 67 GLY GLY B . n B 2 68 ARG 68 68 68 ARG ARG B . n B 2 69 GLU 69 69 69 GLU GLU B . n B 2 70 PHE 70 70 70 PHE PHE B . n B 2 71 ASN 71 71 71 ASN ASN B . n B 2 72 ASN 72 72 72 ASN ASN B . n B 2 73 LEU 73 73 73 LEU LEU B . n B 2 74 GLU 74 74 74 GLU GLU B . n B 2 75 ARG 75 75 75 ARG ARG B . n B 2 76 ARG 76 76 76 ARG ARG B . n B 2 77 ILE 77 77 77 ILE ILE B . n B 2 78 GLU 78 78 78 GLU GLU B . n B 2 79 ASN 79 79 79 ASN ASN B . n B 2 80 LEU 80 80 80 LEU LEU B . n B 2 81 ASN 81 81 81 ASN ASN B . n B 2 82 LYS 82 82 82 LYS LYS B . n B 2 83 LYS 83 83 83 LYS LYS B . n B 2 84 MET 84 84 84 MET MET B . n B 2 85 GLU 85 85 85 GLU GLU B . n B 2 86 ASP 86 86 86 ASP ASP B . n B 2 87 GLY 87 87 87 GLY GLY B . n B 2 88 PHE 88 88 88 PHE PHE B . n B 2 89 LEU 89 89 89 LEU LEU B . n B 2 90 ASP 90 90 90 ASP ASP B . n B 2 91 VAL 91 91 91 VAL VAL B . n B 2 92 TRP 92 92 92 TRP TRP B . n B 2 93 THR 93 93 93 THR THR B . n B 2 94 TYR 94 94 94 TYR TYR B . n B 2 95 ASN 95 95 95 ASN ASN B . n B 2 96 ALA 96 96 96 ALA ALA B . n B 2 97 GLU 97 97 97 GLU GLU B . n B 2 98 LEU 98 98 98 LEU LEU B . n B 2 99 LEU 99 99 99 LEU LEU B . n B 2 100 VAL 100 100 100 VAL VAL B . n B 2 101 LEU 101 101 101 LEU LEU B . n B 2 102 MET 102 102 102 MET MET B . n B 2 103 GLU 103 103 103 GLU GLU B . n B 2 104 ASN 104 104 104 ASN ASN B . n B 2 105 GLU 105 105 105 GLU GLU B . n B 2 106 ARG 106 106 106 ARG ARG B . n B 2 107 THR 107 107 107 THR THR B . n B 2 108 LEU 108 108 108 LEU LEU B . n B 2 109 ASP 109 109 109 ASP ASP B . n B 2 110 PHE 110 110 110 PHE PHE B . n B 2 111 HIS 111 111 111 HIS HIS B . n B 2 112 ASP 112 112 112 ASP ASP B . n B 2 113 SER 113 113 113 SER SER B . n B 2 114 ASN 114 114 114 ASN ASN B . n B 2 115 VAL 115 115 115 VAL VAL B . n B 2 116 LYS 116 116 116 LYS LYS B . n B 2 117 ASN 117 117 117 ASN ASN B . n B 2 118 LEU 118 118 118 LEU LEU B . n B 2 119 TYR 119 119 119 TYR TYR B . n B 2 120 ASP 120 120 120 ASP ASP B . n B 2 121 LYS 121 121 121 LYS LYS B . n B 2 122 VAL 122 122 122 VAL VAL B . n B 2 123 ARG 123 123 123 ARG ARG B . n B 2 124 LEU 124 124 124 LEU LEU B . n B 2 125 GLN 125 125 125 GLN GLN B . n B 2 126 LEU 126 126 126 LEU LEU B . n B 2 127 ARG 127 127 127 ARG ARG B . n B 2 128 ASP 128 128 128 ASP ASP B . n B 2 129 ASN 129 129 129 ASN ASN B . n B 2 130 ALA 130 130 130 ALA ALA B . n B 2 131 LYS 131 131 131 LYS LYS B . n B 2 132 GLU 132 132 132 GLU GLU B . n B 2 133 LEU 133 133 133 LEU LEU B . n B 2 134 GLY 134 134 134 GLY GLY B . n B 2 135 ASN 135 135 135 ASN ASN B . n B 2 136 GLY 136 136 136 GLY GLY B . n B 2 137 CYS 137 137 137 CYS CYS B . n B 2 138 PHE 138 138 138 PHE PHE B . n B 2 139 GLU 139 139 139 GLU GLU B . n B 2 140 PHE 140 140 140 PHE PHE B . n B 2 141 TYR 141 141 141 TYR TYR B . n B 2 142 HIS 142 142 142 HIS HIS B . n B 2 143 LYS 143 143 143 LYS LYS B . n B 2 144 CYS 144 144 144 CYS CYS B . n B 2 145 ASP 145 145 145 ASP ASP B . n B 2 146 ASN 146 146 146 ASN ASN B . n B 2 147 GLU 147 147 147 GLU GLU B . n B 2 148 CYS 148 148 148 CYS CYS B . n B 2 149 MET 149 149 149 MET MET B . n B 2 150 GLU 150 150 150 GLU GLU B . n B 2 151 SER 151 151 151 SER SER B . n B 2 152 VAL 152 152 152 VAL VAL B . n B 2 153 ARG 153 153 153 ARG ARG B . n B 2 154 ASN 154 154 154 ASN ASN B . n B 2 155 GLY 155 155 155 GLY GLY B . n B 2 156 THR 156 156 156 THR THR B . n B 2 157 TYR 157 157 157 TYR TYR B . n B 2 158 ASP 158 158 158 ASP ASP B . n B 2 159 TYR 159 159 159 TYR TYR B . n B 2 160 PRO 160 160 160 PRO PRO B . n B 2 161 GLN 161 161 161 GLN GLN B . n B 2 162 TYR 162 162 162 TYR TYR B . n B 2 163 SER 163 163 163 SER SER B . n B 2 164 GLU 164 164 164 GLU GLU B . n B 2 165 GLU 165 165 165 GLU GLU B . n B 2 166 ALA 166 166 166 ALA ALA B . n B 2 167 ARG 167 167 167 ARG ARG B . n B 2 168 LEU 168 168 168 LEU LEU B . n B 2 169 LYS 169 169 169 LYS LYS B . n B 2 170 ARG 170 170 170 ARG ARG B . n B 2 171 GLU 171 171 171 GLU GLU B . n B 2 172 GLU 172 172 172 GLU GLU B . n B 2 173 ILE 173 173 173 ILE ILE B . n B 2 174 SER 174 174 174 SER SER B . n B 2 175 SER 175 175 175 SER SER B . n B 2 176 GLY 176 176 176 GLY GLY B . n B 2 177 ARG 177 177 ? ? ? B . n C 3 1 GLN 1 1 1 GLN GLN H . n C 3 2 VAL 2 2 2 VAL VAL H . n C 3 3 GLN 3 3 3 GLN GLN H . n C 3 4 LEU 4 4 4 LEU LEU H . n C 3 5 VAL 5 5 5 VAL VAL H . n C 3 6 GLN 6 6 6 GLN GLN H . n C 3 7 SER 7 7 7 SER SER H . n C 3 8 GLY 8 8 8 GLY GLY H . n C 3 9 ALA 9 9 9 ALA ALA H . n C 3 10 GLU 10 10 10 GLU GLU H . n C 3 11 VAL 11 11 11 VAL VAL H . n C 3 12 LYS 12 12 12 LYS LYS H . n C 3 13 LYS 13 13 13 LYS LYS H . n C 3 14 PRO 14 14 14 PRO PRO H . n C 3 15 GLY 15 15 15 GLY GLY H . n C 3 16 SER 16 16 16 SER SER H . n C 3 17 SER 17 17 17 SER SER H . n C 3 18 VAL 18 18 18 VAL VAL H . n C 3 19 LYS 19 19 19 LYS LYS H . n C 3 20 VAL 20 20 20 VAL VAL H . n C 3 21 SER 21 21 21 SER SER H . n C 3 22 CYS 22 22 22 CYS CYS H . n C 3 23 LYS 23 23 23 LYS LYS H . n C 3 24 SER 24 24 24 SER SER H . n C 3 25 SER 25 25 25 SER SER H . n C 3 26 GLY 26 26 26 GLY GLY H . n C 3 27 GLY 27 27 27 GLY GLY H . n C 3 28 THR 28 28 28 THR THR H . n C 3 29 SER 29 29 29 SER SER H . n C 3 30 ASN 30 30 30 ASN ASN H . n C 3 31 ASN 31 31 31 ASN ASN H . n C 3 32 TYR 32 32 32 TYR TYR H . n C 3 33 ALA 33 33 33 ALA ALA H . n C 3 34 ILE 34 34 34 ILE ILE H . n C 3 35 SER 35 35 35 SER SER H . n C 3 36 TRP 36 36 36 TRP TRP H . n C 3 37 VAL 37 37 37 VAL VAL H . n C 3 38 ARG 38 38 38 ARG ARG H . n C 3 39 GLN 39 39 39 GLN GLN H . n C 3 40 ALA 40 40 40 ALA ALA H . n C 3 41 PRO 41 41 41 PRO PRO H . n C 3 42 GLY 42 42 42 GLY GLY H . n C 3 43 GLN 43 43 43 GLN GLN H . n C 3 44 GLY 44 44 44 GLY GLY H . n C 3 45 LEU 45 45 45 LEU LEU H . n C 3 46 ASP 46 46 46 ASP ASP H . n C 3 47 TRP 47 47 47 TRP TRP H . n C 3 48 MET 48 48 48 MET MET H . n C 3 49 GLY 49 49 49 GLY GLY H . n C 3 50 GLY 50 50 50 GLY GLY H . n C 3 51 ILE 51 51 51 ILE ILE H . n C 3 52 SER 52 52 52 SER SER H . n C 3 53 PRO 53 52 52 PRO PRO H A n C 3 54 ILE 54 53 53 ILE ILE H . n C 3 55 PHE 55 54 54 PHE PHE H . n C 3 56 GLY 56 55 55 GLY GLY H . n C 3 57 SER 57 56 56 SER SER H . n C 3 58 THR 58 57 57 THR THR H . n C 3 59 ALA 59 58 58 ALA ALA H . n C 3 60 TYR 60 59 59 TYR TYR H . n C 3 61 ALA 61 60 60 ALA ALA H . n C 3 62 GLN 62 61 61 GLN GLN H . n C 3 63 LYS 63 62 62 LYS LYS H . n C 3 64 PHE 64 63 63 PHE PHE H . n C 3 65 GLN 65 64 64 GLN GLN H . n C 3 66 GLY 66 65 65 GLY GLY H . n C 3 67 ARG 67 66 66 ARG ARG H . n C 3 68 VAL 68 67 67 VAL VAL H . n C 3 69 THR 69 68 68 THR THR H . n C 3 70 ILE 70 69 69 ILE ILE H . n C 3 71 SER 71 70 70 SER SER H . n C 3 72 ALA 72 71 71 ALA ALA H . n C 3 73 ASP 73 72 72 ASP ASP H . n C 3 74 ILE 74 73 73 ILE ILE H . n C 3 75 PHE 75 74 74 PHE PHE H . n C 3 76 SER 76 75 75 SER SER H . n C 3 77 ASN 77 76 76 ASN ASN H . n C 3 78 THR 78 77 77 THR THR H . n C 3 79 ALA 79 78 78 ALA ALA H . n C 3 80 TYR 80 79 79 TYR TYR H . n C 3 81 MET 81 80 80 MET MET H . n C 3 82 GLU 82 81 81 GLU GLU H . n C 3 83 LEU 83 82 82 LEU LEU H . n C 3 84 ASN 84 82 82 ASN ASN H A n C 3 85 SER 85 82 82 SER SER H B n C 3 86 LEU 86 82 82 LEU LEU H C n C 3 87 THR 87 83 83 THR THR H . n C 3 88 SER 88 84 84 SER SER H . n C 3 89 GLU 89 85 85 GLU GLU H . n C 3 90 ASP 90 86 86 ASP ASP H . n C 3 91 THR 91 87 87 THR THR H . n C 3 92 ALA 92 88 88 ALA ALA H . n C 3 93 VAL 93 89 89 VAL VAL H . n C 3 94 TYR 94 90 90 TYR TYR H . n C 3 95 PHE 95 91 91 PHE PHE H . n C 3 96 CYS 96 92 92 CYS CYS H . n C 3 97 ALA 97 93 93 ALA ALA H . n C 3 98 ARG 98 94 94 ARG ARG H . n C 3 99 HIS 99 95 95 HIS HIS H . n C 3 100 GLY 100 96 96 GLY GLY H . n C 3 101 ASN 101 97 97 ASN ASN H . n C 3 102 TYR 102 98 98 TYR TYR H . n C 3 103 TYR 103 99 99 TYR TYR H . n C 3 104 TYR 104 100 100 TYR TYR H . n C 3 105 TYR 105 100 100 TYR TYR H A n C 3 106 SER 106 100 100 SER SER H B n C 3 107 GLY 107 100 100 GLY GLY H C n C 3 108 MET 108 100 100 MET MET H D n C 3 109 ASP 109 101 101 ASP ASP H . n C 3 110 VAL 110 102 102 VAL VAL H . n C 3 111 TRP 111 103 103 TRP TRP H . n C 3 112 GLY 112 104 104 GLY GLY H . n C 3 113 GLN 113 105 105 GLN GLN H . n C 3 114 GLY 114 106 106 GLY GLY H . n C 3 115 THR 115 107 107 THR THR H . n C 3 116 THR 116 108 108 THR THR H . n C 3 117 VAL 117 109 109 VAL VAL H . n C 3 118 THR 118 110 110 THR THR H . n C 3 119 VAL 119 111 111 VAL VAL H . n C 3 120 SER 120 112 112 SER SER H . n C 3 121 SER 121 113 113 SER SER H . n C 3 122 ALA 122 114 114 ALA ALA H . n C 3 123 SER 123 115 115 SER SER H . n C 3 124 THR 124 116 116 THR THR H . n C 3 125 LYS 125 117 117 LYS LYS H . n C 3 126 GLY 126 118 118 GLY GLY H . n C 3 127 PRO 127 119 119 PRO PRO H . n C 3 128 SER 128 120 120 SER SER H . n C 3 129 VAL 129 121 121 VAL VAL H . n C 3 130 PHE 130 122 122 PHE PHE H . n C 3 131 PRO 131 123 123 PRO PRO H . n C 3 132 LEU 132 124 124 LEU LEU H . n C 3 133 ALA 133 125 125 ALA ALA H . n C 3 134 PRO 134 126 126 PRO PRO H . n C 3 135 SER 135 127 ? ? ? H . n C 3 136 SER 136 128 ? ? ? H . n C 3 137 LYS 137 129 ? ? ? H . n C 3 138 SER 138 130 ? ? ? H . n C 3 139 THR 139 131 ? ? ? H . n C 3 140 SER 140 132 ? ? ? H . n C 3 141 GLY 141 133 133 GLY GLY H . n C 3 142 GLY 142 134 134 GLY GLY H . n C 3 143 THR 143 135 135 THR THR H . n C 3 144 ALA 144 136 136 ALA ALA H . n C 3 145 ALA 145 137 137 ALA ALA H . n C 3 146 LEU 146 138 138 LEU LEU H . n C 3 147 GLY 147 139 139 GLY GLY H . n C 3 148 CYS 148 140 140 CYS CYS H . n C 3 149 LEU 149 141 141 LEU LEU H . n C 3 150 VAL 150 142 142 VAL VAL H . n C 3 151 LYS 151 143 143 LYS LYS H . n C 3 152 ASP 152 144 144 ASP ASP H . n C 3 153 TYR 153 145 145 TYR TYR H . n C 3 154 PHE 154 146 146 PHE PHE H . n C 3 155 PRO 155 147 147 PRO PRO H . n C 3 156 GLU 156 148 148 GLU GLU H . n C 3 157 PRO 157 149 149 PRO PRO H . n C 3 158 VAL 158 150 150 VAL VAL H . n C 3 159 THR 159 151 151 THR THR H . n C 3 160 VAL 160 152 152 VAL VAL H . n C 3 161 SER 161 153 153 SER SER H . n C 3 162 TRP 162 154 154 TRP TRP H . n C 3 163 ASN 163 155 155 ASN ASN H . n C 3 164 SER 164 156 156 SER SER H . n C 3 165 GLY 165 157 157 GLY GLY H . n C 3 166 ALA 166 158 158 ALA ALA H . n C 3 167 LEU 167 159 159 LEU LEU H . n C 3 168 THR 168 160 160 THR THR H . n C 3 169 SER 169 161 161 SER SER H . n C 3 170 GLY 170 162 162 GLY GLY H . n C 3 171 VAL 171 163 163 VAL VAL H . n C 3 172 HIS 172 164 164 HIS HIS H . n C 3 173 THR 173 165 165 THR THR H . n C 3 174 PHE 174 166 166 PHE PHE H . n C 3 175 PRO 175 167 167 PRO PRO H . n C 3 176 ALA 176 168 168 ALA ALA H . n C 3 177 VAL 177 169 169 VAL VAL H . n C 3 178 LEU 178 170 170 LEU LEU H . n C 3 179 GLN 179 171 171 GLN GLN H . n C 3 180 SER 180 172 172 SER SER H . n C 3 181 SER 181 173 173 SER SER H . n C 3 182 GLY 182 174 174 GLY GLY H . n C 3 183 LEU 183 175 175 LEU LEU H . n C 3 184 TYR 184 176 176 TYR TYR H . n C 3 185 SER 185 177 177 SER SER H . n C 3 186 LEU 186 178 178 LEU LEU H . n C 3 187 SER 187 179 179 SER SER H . n C 3 188 SER 188 180 180 SER SER H . n C 3 189 VAL 189 181 181 VAL VAL H . n C 3 190 VAL 190 182 182 VAL VAL H . n C 3 191 THR 191 183 183 THR THR H . n C 3 192 VAL 192 184 184 VAL VAL H . n C 3 193 PRO 193 185 185 PRO PRO H . n C 3 194 SER 194 186 186 SER SER H . n C 3 195 SER 195 187 187 SER SER H . n C 3 196 SER 196 188 188 SER SER H . n C 3 197 LEU 197 189 189 LEU LEU H . n C 3 198 GLY 198 190 190 GLY GLY H . n C 3 199 THR 199 191 191 THR THR H . n C 3 200 GLN 200 192 192 GLN GLN H . n C 3 201 THR 201 193 193 THR THR H . n C 3 202 TYR 202 194 194 TYR TYR H . n C 3 203 ILE 203 195 195 ILE ILE H . n C 3 204 CYS 204 196 196 CYS CYS H . n C 3 205 ASN 205 197 197 ASN ASN H . n C 3 206 VAL 206 198 198 VAL VAL H . n C 3 207 ASN 207 199 199 ASN ASN H . n C 3 208 HIS 208 200 200 HIS HIS H . n C 3 209 LYS 209 201 201 LYS LYS H . n C 3 210 PRO 210 202 202 PRO PRO H . n C 3 211 SER 211 203 203 SER SER H . n C 3 212 ASN 212 204 204 ASN ASN H . n C 3 213 THR 213 205 205 THR THR H . n C 3 214 LYS 214 206 206 LYS LYS H . n C 3 215 VAL 215 207 207 VAL VAL H . n C 3 216 ASP 216 208 208 ASP ASP H . n C 3 217 LYS 217 209 209 LYS LYS H . n C 3 218 ARG 218 210 210 ARG ARG H . n C 3 219 VAL 219 211 211 VAL VAL H . n C 3 220 GLU 220 212 212 GLU GLU H . n C 3 221 PRO 221 213 213 PRO PRO H . n C 3 222 LYS 222 214 ? ? ? H . n C 3 223 SER 223 215 ? ? ? H . n C 3 224 CYS 224 216 ? ? ? H . n C 3 225 HIS 225 217 ? ? ? H . n C 3 226 HIS 226 218 ? ? ? H . n C 3 227 HIS 227 219 ? ? ? H . n C 3 228 HIS 228 220 ? ? ? H . n C 3 229 HIS 229 221 ? ? ? H . n C 3 230 HIS 230 222 ? ? ? H . n D 4 1 GLN 1 1 ? ? ? L . n D 4 2 SER 2 2 2 SER SER L . n D 4 3 ALA 3 3 3 ALA ALA L . n D 4 4 LEU 4 4 4 LEU LEU L . n D 4 5 THR 5 5 5 THR THR L . n D 4 6 GLN 6 6 6 GLN GLN L . n D 4 7 PRO 7 7 7 PRO PRO L . n D 4 8 PRO 8 8 8 PRO PRO L . n D 4 9 ALA 9 9 9 ALA ALA L . n D 4 10 VAL 10 11 11 VAL VAL L . n D 4 11 SER 11 12 12 SER SER L . n D 4 12 GLY 12 13 13 GLY GLY L . n D 4 13 THR 13 14 14 THR THR L . n D 4 14 PRO 14 15 15 PRO PRO L . n D 4 15 GLY 15 16 16 GLY GLY L . n D 4 16 GLN 16 17 17 GLN GLN L . n D 4 17 ARG 17 18 18 ARG ARG L . n D 4 18 VAL 18 19 19 VAL VAL L . n D 4 19 THR 19 20 20 THR THR L . n D 4 20 ILE 20 21 21 ILE ILE L . n D 4 21 SER 21 22 22 SER SER L . n D 4 22 CYS 22 23 23 CYS CYS L . n D 4 23 SER 23 24 24 SER SER L . n D 4 24 GLY 24 25 25 GLY GLY L . n D 4 25 SER 25 26 26 SER SER L . n D 4 26 ASP 26 27 27 ASP ASP L . n D 4 27 SER 27 27 27 SER SER L A n D 4 28 ASN 28 27 27 ASN ASN L B n D 4 29 ILE 29 28 28 ILE ILE L . n D 4 30 GLY 30 29 29 GLY GLY L . n D 4 31 ARG 31 30 30 ARG ARG L . n D 4 32 ARG 32 31 31 ARG ARG L . n D 4 33 SER 33 32 32 SER SER L . n D 4 34 VAL 34 33 33 VAL VAL L . n D 4 35 ASN 35 34 34 ASN ASN L . n D 4 36 TRP 36 35 35 TRP TRP L . n D 4 37 TYR 37 36 36 TYR TYR L . n D 4 38 GLN 38 37 37 GLN GLN L . n D 4 39 GLN 39 38 38 GLN GLN L . n D 4 40 PHE 40 39 39 PHE PHE L . n D 4 41 PRO 41 40 40 PRO PRO L . n D 4 42 GLY 42 41 41 GLY GLY L . n D 4 43 THR 43 42 42 THR THR L . n D 4 44 ALA 44 43 43 ALA ALA L . n D 4 45 PRO 45 44 44 PRO PRO L . n D 4 46 LYS 46 45 45 LYS LYS L . n D 4 47 LEU 47 46 46 LEU LEU L . n D 4 48 LEU 48 47 47 LEU LEU L . n D 4 49 ILE 49 48 48 ILE ILE L . n D 4 50 TYR 50 49 49 TYR TYR L . n D 4 51 SER 51 50 50 SER SER L . n D 4 52 ASN 52 51 51 ASN ASN L . n D 4 53 ASP 53 52 52 ASP ASP L . n D 4 54 GLN 54 53 53 GLN GLN L . n D 4 55 ARG 55 54 54 ARG ARG L . n D 4 56 PRO 56 55 55 PRO PRO L . n D 4 57 SER 57 56 56 SER SER L . n D 4 58 VAL 58 57 57 VAL VAL L . n D 4 59 VAL 59 58 58 VAL VAL L . n D 4 60 PRO 60 59 59 PRO PRO L . n D 4 61 ASP 61 60 60 ASP ASP L . n D 4 62 ARG 62 61 61 ARG ARG L . n D 4 63 PHE 63 62 62 PHE PHE L . n D 4 64 SER 64 63 63 SER SER L . n D 4 65 GLY 65 64 64 GLY GLY L . n D 4 66 SER 66 65 65 SER SER L . n D 4 67 LYS 67 66 66 LYS LYS L . n D 4 68 SER 68 67 67 SER SER L . n D 4 69 GLY 69 68 68 GLY GLY L . n D 4 70 THR 70 69 69 THR THR L . n D 4 71 SER 71 70 70 SER SER L . n D 4 72 ALA 72 71 71 ALA ALA L . n D 4 73 SER 73 72 72 SER SER L . n D 4 74 LEU 74 73 73 LEU LEU L . n D 4 75 ALA 75 74 74 ALA ALA L . n D 4 76 ILE 76 75 75 ILE ILE L . n D 4 77 SER 77 76 76 SER SER L . n D 4 78 GLY 78 77 77 GLY GLY L . n D 4 79 LEU 79 78 78 LEU LEU L . n D 4 80 GLN 80 79 79 GLN GLN L . n D 4 81 SER 81 80 80 SER SER L . n D 4 82 GLU 82 81 81 GLU GLU L . n D 4 83 ASP 83 82 82 ASP ASP L . n D 4 84 GLU 84 83 83 GLU GLU L . n D 4 85 ALA 85 84 84 ALA ALA L . n D 4 86 GLU 86 85 85 GLU GLU L . n D 4 87 TYR 87 86 86 TYR TYR L . n D 4 88 TYR 88 87 87 TYR TYR L . n D 4 89 CYS 89 88 88 CYS CYS L . n D 4 90 ALA 90 89 89 ALA ALA L . n D 4 91 ALA 91 90 90 ALA ALA L . n D 4 92 TRP 92 91 91 TRP TRP L . n D 4 93 ASP 93 92 92 ASP ASP L . n D 4 94 ASP 94 93 93 ASP ASP L . n D 4 95 SER 95 94 94 SER SER L . n D 4 96 LEU 96 95 95 LEU LEU L . n D 4 97 LYS 97 95 95 LYS LYS L A n D 4 98 GLY 98 95 95 GLY GLY L B n D 4 99 ALA 99 96 96 ALA ALA L . n D 4 100 VAL 100 97 97 VAL VAL L . n D 4 101 PHE 101 98 98 PHE PHE L . n D 4 102 GLY 102 99 99 GLY GLY L . n D 4 103 GLY 103 100 100 GLY GLY L . n D 4 104 GLY 104 101 101 GLY GLY L . n D 4 105 THR 105 102 102 THR THR L . n D 4 106 GLN 106 103 103 GLN GLN L . n D 4 107 LEU 107 104 104 LEU LEU L . n D 4 108 THR 108 105 105 THR THR L . n D 4 109 VAL 109 106 106 VAL VAL L . n D 4 110 LEU 110 106 106 LEU LEU L A n D 4 111 GLY 111 107 107 GLY GLY L . n D 4 112 GLN 112 108 108 GLN GLN L . n D 4 113 PRO 113 109 109 PRO PRO L . n D 4 114 LYS 114 110 110 LYS LYS L . n D 4 115 ALA 115 111 111 ALA ALA L . n D 4 116 ALA 116 112 112 ALA ALA L . n D 4 117 PRO 117 113 113 PRO PRO L . n D 4 118 SER 118 114 114 SER SER L . n D 4 119 VAL 119 115 115 VAL VAL L . n D 4 120 THR 120 116 116 THR THR L . n D 4 121 LEU 121 117 117 LEU LEU L . n D 4 122 PHE 122 118 118 PHE PHE L . n D 4 123 PRO 123 119 119 PRO PRO L . n D 4 124 PRO 124 120 120 PRO PRO L . n D 4 125 SER 125 121 121 SER SER L . n D 4 126 SER 126 122 122 SER SER L . n D 4 127 GLU 127 123 123 GLU GLU L . n D 4 128 GLU 128 124 124 GLU GLU L . n D 4 129 LEU 129 125 125 LEU LEU L . n D 4 130 GLN 130 126 126 GLN GLN L . n D 4 131 ALA 131 127 127 ALA ALA L . n D 4 132 ASN 132 128 128 ASN ASN L . n D 4 133 LYS 133 129 129 LYS LYS L . n D 4 134 ALA 134 130 130 ALA ALA L . n D 4 135 THR 135 131 131 THR THR L . n D 4 136 LEU 136 132 132 LEU LEU L . n D 4 137 VAL 137 133 133 VAL VAL L . n D 4 138 CYS 138 134 134 CYS CYS L . n D 4 139 LEU 139 135 135 LEU LEU L . n D 4 140 ILE 140 136 136 ILE ILE L . n D 4 141 SER 141 137 137 SER SER L . n D 4 142 ASP 142 138 138 ASP ASP L . n D 4 143 PHE 143 139 139 PHE PHE L . n D 4 144 TYR 144 140 140 TYR TYR L . n D 4 145 PRO 145 141 141 PRO PRO L . n D 4 146 GLY 146 142 142 GLY GLY L . n D 4 147 ALA 147 143 143 ALA ALA L . n D 4 148 VAL 148 144 144 VAL VAL L . n D 4 149 THR 149 145 145 THR THR L . n D 4 150 VAL 150 146 146 VAL VAL L . n D 4 151 ALA 151 147 147 ALA ALA L . n D 4 152 TRP 152 148 148 TRP TRP L . n D 4 153 LYS 153 149 149 LYS LYS L . n D 4 154 ALA 154 150 150 ALA ALA L . n D 4 155 ASP 155 151 151 ASP ASP L . n D 4 156 SER 156 152 152 SER SER L . n D 4 157 SER 157 153 153 SER SER L . n D 4 158 PRO 158 154 154 PRO PRO L . n D 4 159 VAL 159 155 155 VAL VAL L . n D 4 160 LYS 160 156 156 LYS LYS L . n D 4 161 ALA 161 157 157 ALA ALA L . n D 4 162 GLY 162 158 158 GLY GLY L . n D 4 163 VAL 163 159 159 VAL VAL L . n D 4 164 GLU 164 160 160 GLU GLU L . n D 4 165 THR 165 161 161 THR THR L . n D 4 166 THR 166 162 162 THR THR L . n D 4 167 THR 167 163 163 THR THR L . n D 4 168 PRO 168 164 164 PRO PRO L . n D 4 169 SER 169 165 165 SER SER L . n D 4 170 LYS 170 166 166 LYS LYS L . n D 4 171 GLN 171 167 167 GLN GLN L . n D 4 172 SER 172 168 168 SER SER L . n D 4 173 ASN 173 169 169 ASN ASN L . n D 4 174 ASN 174 170 170 ASN ASN L . n D 4 175 LYS 175 171 171 LYS LYS L . n D 4 176 TYR 176 172 172 TYR TYR L . n D 4 177 ALA 177 173 173 ALA ALA L . n D 4 178 ALA 178 174 174 ALA ALA L . n D 4 179 SER 179 175 175 SER SER L . n D 4 180 SER 180 176 176 SER SER L . n D 4 181 TYR 181 177 177 TYR TYR L . n D 4 182 LEU 182 178 178 LEU LEU L . n D 4 183 SER 183 179 179 SER SER L . n D 4 184 LEU 184 180 180 LEU LEU L . n D 4 185 THR 185 181 181 THR THR L . n D 4 186 PRO 186 182 182 PRO PRO L . n D 4 187 GLU 187 183 183 GLU GLU L . n D 4 188 GLN 188 184 184 GLN GLN L . n D 4 189 TRP 189 185 185 TRP TRP L . n D 4 190 LYS 190 186 186 LYS LYS L . n D 4 191 SER 191 187 187 SER SER L . n D 4 192 HIS 192 188 188 HIS HIS L . n D 4 193 ARG 193 189 189 ARG ARG L . n D 4 194 SER 194 190 190 SER SER L . n D 4 195 TYR 195 191 191 TYR TYR L . n D 4 196 SER 196 192 192 SER SER L . n D 4 197 CYS 197 193 193 CYS CYS L . n D 4 198 GLN 198 194 194 GLN GLN L . n D 4 199 VAL 199 195 195 VAL VAL L . n D 4 200 THR 200 196 196 THR THR L . n D 4 201 HIS 201 197 197 HIS HIS L . n D 4 202 GLU 202 198 198 GLU GLU L . n D 4 203 GLY 203 199 199 GLY GLY L . n D 4 204 SER 204 200 200 SER SER L . n D 4 205 THR 205 201 201 THR THR L . n D 4 206 VAL 206 202 202 VAL VAL L . n D 4 207 GLU 207 203 203 GLU GLU L . n D 4 208 LYS 208 204 204 LYS LYS L . n D 4 209 THR 209 205 205 THR THR L . n D 4 210 VAL 210 206 206 VAL VAL L . n D 4 211 ALA 211 207 207 ALA ALA L . n D 4 212 PRO 212 208 208 PRO PRO L . n D 4 213 THR 213 209 ? ? ? L . n D 4 214 GLU 214 210 ? ? ? L . n D 4 215 CYS 215 211 ? ? ? L . n D 4 216 SER 216 212 ? ? ? L . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code E 5 EDO 1 401 336 EDO EDO A . F 5 EDO 1 402 337 EDO EDO A . G 5 EDO 1 403 338 EDO EDO A . H 5 EDO 1 404 339 EDO EDO A . I 6 NAG 1 405 401 NAG NAG A . J 5 EDO 1 406 342 EDO EDO A . K 6 NAG 1 407 601 NAG NAG A . L 6 NAG 2 408 602 NAG NAG A . M 6 NAG 1 409 501 NAG NAG A . N 7 GOL 1 201 341 GOL GOL B . O 5 EDO 1 202 340 EDO EDO B . P 5 EDO 1 203 182 EDO EDO B . Q 5 EDO 1 204 183 EDO EDO B . R 5 EDO 1 205 184 EDO EDO B . S 5 EDO 1 206 186 EDO EDO B . T 6 NAG 1 207 201 NAG NAG B . U 5 EDO 1 301 181 EDO EDO H . V 8 HOH 1 501 4 HOH HOH A . V 8 HOH 2 502 6 HOH HOH A . V 8 HOH 3 503 7 HOH HOH A . V 8 HOH 4 504 8 HOH HOH A . V 8 HOH 5 505 9 HOH HOH A . V 8 HOH 6 506 11 HOH HOH A . V 8 HOH 7 507 13 HOH HOH A . V 8 HOH 8 508 19 HOH HOH A . V 8 HOH 9 509 21 HOH HOH A . V 8 HOH 10 510 24 HOH HOH A . V 8 HOH 11 511 25 HOH HOH A . V 8 HOH 12 512 28 HOH HOH A . V 8 HOH 13 513 32 HOH HOH A . V 8 HOH 14 514 34 HOH HOH A . V 8 HOH 15 515 37 HOH HOH A . V 8 HOH 16 516 39 HOH HOH A . V 8 HOH 17 517 43 HOH HOH A . V 8 HOH 18 518 44 HOH HOH A . V 8 HOH 19 519 47 HOH HOH A . V 8 HOH 20 520 48 HOH HOH A . V 8 HOH 21 521 51 HOH HOH A . V 8 HOH 22 522 56 HOH HOH A . V 8 HOH 23 523 60 HOH HOH A . V 8 HOH 24 524 61 HOH HOH A . V 8 HOH 25 525 63 HOH HOH A . V 8 HOH 26 526 64 HOH HOH A . V 8 HOH 27 527 65 HOH HOH A . V 8 HOH 28 528 79 HOH HOH A . V 8 HOH 29 529 80 HOH HOH A . V 8 HOH 30 530 86 HOH HOH A . V 8 HOH 31 531 89 HOH HOH A . V 8 HOH 32 532 91 HOH HOH A . V 8 HOH 33 533 95 HOH HOH A . V 8 HOH 34 534 96 HOH HOH A . V 8 HOH 35 535 98 HOH HOH A . V 8 HOH 36 536 99 HOH HOH A . V 8 HOH 37 537 100 HOH HOH A . V 8 HOH 38 538 103 HOH HOH A . V 8 HOH 39 539 104 HOH HOH A . V 8 HOH 40 540 106 HOH HOH A . V 8 HOH 41 541 109 HOH HOH A . V 8 HOH 42 542 110 HOH HOH A . V 8 HOH 43 543 115 HOH HOH A . V 8 HOH 44 544 118 HOH HOH A . V 8 HOH 45 545 119 HOH HOH A . V 8 HOH 46 546 120 HOH HOH A . V 8 HOH 47 547 124 HOH HOH A . V 8 HOH 48 548 125 HOH HOH A . V 8 HOH 49 549 129 HOH HOH A . V 8 HOH 50 550 130 HOH HOH A . V 8 HOH 51 551 132 HOH HOH A . V 8 HOH 52 552 133 HOH HOH A . V 8 HOH 53 553 135 HOH HOH A . V 8 HOH 54 554 136 HOH HOH A . V 8 HOH 55 555 137 HOH HOH A . V 8 HOH 56 556 139 HOH HOH A . V 8 HOH 57 557 142 HOH HOH A . V 8 HOH 58 558 148 HOH HOH A . V 8 HOH 59 559 151 HOH HOH A . V 8 HOH 60 560 154 HOH HOH A . V 8 HOH 61 561 156 HOH HOH A . V 8 HOH 62 562 159 HOH HOH A . V 8 HOH 63 563 161 HOH HOH A . V 8 HOH 64 564 164 HOH HOH A . V 8 HOH 65 565 166 HOH HOH A . V 8 HOH 66 566 167 HOH HOH A . V 8 HOH 67 567 168 HOH HOH A . V 8 HOH 68 568 169 HOH HOH A . V 8 HOH 69 569 170 HOH HOH A . V 8 HOH 70 570 172 HOH HOH A . V 8 HOH 71 571 176 HOH HOH A . V 8 HOH 72 572 177 HOH HOH A . V 8 HOH 73 573 185 HOH HOH A . V 8 HOH 74 574 188 HOH HOH A . V 8 HOH 75 575 190 HOH HOH A . V 8 HOH 76 576 191 HOH HOH A . V 8 HOH 77 577 193 HOH HOH A . V 8 HOH 78 578 194 HOH HOH A . V 8 HOH 79 579 195 HOH HOH A . V 8 HOH 80 580 196 HOH HOH A . V 8 HOH 81 581 198 HOH HOH A . V 8 HOH 82 582 201 HOH HOH A . V 8 HOH 83 583 204 HOH HOH A . V 8 HOH 84 584 205 HOH HOH A . V 8 HOH 85 585 207 HOH HOH A . V 8 HOH 86 586 214 HOH HOH A . V 8 HOH 87 587 217 HOH HOH A . V 8 HOH 88 588 218 HOH HOH A . V 8 HOH 89 589 221 HOH HOH A . V 8 HOH 90 590 223 HOH HOH A . V 8 HOH 91 591 224 HOH HOH A . V 8 HOH 92 592 225 HOH HOH A . V 8 HOH 93 593 226 HOH HOH A . V 8 HOH 94 594 227 HOH HOH A . V 8 HOH 95 595 228 HOH HOH A . V 8 HOH 96 596 229 HOH HOH A . V 8 HOH 97 597 235 HOH HOH A . V 8 HOH 98 598 241 HOH HOH A . V 8 HOH 99 599 243 HOH HOH A . V 8 HOH 100 600 244 HOH HOH A . V 8 HOH 101 601 245 HOH HOH A . V 8 HOH 102 602 248 HOH HOH A . V 8 HOH 103 603 249 HOH HOH A . V 8 HOH 104 604 250 HOH HOH A . V 8 HOH 105 605 254 HOH HOH A . V 8 HOH 106 606 258 HOH HOH A . V 8 HOH 107 607 259 HOH HOH A . V 8 HOH 108 608 261 HOH HOH A . V 8 HOH 109 609 262 HOH HOH A . V 8 HOH 110 610 266 HOH HOH A . V 8 HOH 111 611 268 HOH HOH A . V 8 HOH 112 612 272 HOH HOH A . V 8 HOH 113 613 273 HOH HOH A . V 8 HOH 114 614 276 HOH HOH A . V 8 HOH 115 615 278 HOH HOH A . V 8 HOH 116 616 281 HOH HOH A . V 8 HOH 117 617 282 HOH HOH A . V 8 HOH 118 618 283 HOH HOH A . V 8 HOH 119 619 284 HOH HOH A . V 8 HOH 120 620 287 HOH HOH A . V 8 HOH 121 621 288 HOH HOH A . V 8 HOH 122 622 291 HOH HOH A . V 8 HOH 123 623 292 HOH HOH A . V 8 HOH 124 624 293 HOH HOH A . V 8 HOH 125 625 294 HOH HOH A . V 8 HOH 126 626 295 HOH HOH A . V 8 HOH 127 627 296 HOH HOH A . V 8 HOH 128 628 298 HOH HOH A . V 8 HOH 129 629 299 HOH HOH A . V 8 HOH 130 630 300 HOH HOH A . V 8 HOH 131 631 302 HOH HOH A . V 8 HOH 132 632 303 HOH HOH A . V 8 HOH 133 633 305 HOH HOH A . V 8 HOH 134 634 309 HOH HOH A . V 8 HOH 135 635 315 HOH HOH A . V 8 HOH 136 636 316 HOH HOH A . V 8 HOH 137 637 319 HOH HOH A . V 8 HOH 138 638 320 HOH HOH A . V 8 HOH 139 639 323 HOH HOH A . V 8 HOH 140 640 329 HOH HOH A . V 8 HOH 141 641 330 HOH HOH A . V 8 HOH 142 642 334 HOH HOH A . V 8 HOH 143 643 335 HOH HOH A . V 8 HOH 144 644 336 HOH HOH A . V 8 HOH 145 645 337 HOH HOH A . V 8 HOH 146 646 339 HOH HOH A . V 8 HOH 147 647 340 HOH HOH A . V 8 HOH 148 648 341 HOH HOH A . V 8 HOH 149 649 344 HOH HOH A . V 8 HOH 150 650 346 HOH HOH A . V 8 HOH 151 651 347 HOH HOH A . V 8 HOH 152 652 351 HOH HOH A . V 8 HOH 153 653 359 HOH HOH A . V 8 HOH 154 654 365 HOH HOH A . V 8 HOH 155 655 368 HOH HOH A . V 8 HOH 156 656 371 HOH HOH A . V 8 HOH 157 657 374 HOH HOH A . V 8 HOH 158 658 375 HOH HOH A . V 8 HOH 159 659 377 HOH HOH A . V 8 HOH 160 660 379 HOH HOH A . V 8 HOH 161 661 380 HOH HOH A . V 8 HOH 162 662 383 HOH HOH A . V 8 HOH 163 663 384 HOH HOH A . V 8 HOH 164 664 385 HOH HOH A . V 8 HOH 165 665 386 HOH HOH A . V 8 HOH 166 666 387 HOH HOH A . V 8 HOH 167 667 390 HOH HOH A . V 8 HOH 168 668 393 HOH HOH A . V 8 HOH 169 669 395 HOH HOH A . V 8 HOH 170 670 398 HOH HOH A . V 8 HOH 171 671 400 HOH HOH A . V 8 HOH 172 672 403 HOH HOH A . V 8 HOH 173 673 404 HOH HOH A . V 8 HOH 174 674 405 HOH HOH A . V 8 HOH 175 675 406 HOH HOH A . V 8 HOH 176 676 412 HOH HOH A . V 8 HOH 177 677 414 HOH HOH A . V 8 HOH 178 678 415 HOH HOH A . V 8 HOH 179 679 416 HOH HOH A . V 8 HOH 180 680 417 HOH HOH A . V 8 HOH 181 681 418 HOH HOH A . V 8 HOH 182 682 420 HOH HOH A . V 8 HOH 183 683 422 HOH HOH A . V 8 HOH 184 684 423 HOH HOH A . V 8 HOH 185 685 426 HOH HOH A . V 8 HOH 186 686 428 HOH HOH A . V 8 HOH 187 687 429 HOH HOH A . V 8 HOH 188 688 430 HOH HOH A . V 8 HOH 189 689 432 HOH HOH A . V 8 HOH 190 690 434 HOH HOH A . V 8 HOH 191 691 435 HOH HOH A . V 8 HOH 192 692 440 HOH HOH A . V 8 HOH 193 693 443 HOH HOH A . V 8 HOH 194 694 446 HOH HOH A . V 8 HOH 195 695 447 HOH HOH A . V 8 HOH 196 696 448 HOH HOH A . V 8 HOH 197 697 449 HOH HOH A . V 8 HOH 198 698 451 HOH HOH A . V 8 HOH 199 699 453 HOH HOH A . V 8 HOH 200 700 455 HOH HOH A . V 8 HOH 201 701 459 HOH HOH A . V 8 HOH 202 702 463 HOH HOH A . V 8 HOH 203 703 464 HOH HOH A . V 8 HOH 204 704 466 HOH HOH A . V 8 HOH 205 705 467 HOH HOH A . V 8 HOH 206 706 472 HOH HOH A . V 8 HOH 207 707 473 HOH HOH A . V 8 HOH 208 708 474 HOH HOH A . V 8 HOH 209 709 475 HOH HOH A . V 8 HOH 210 710 476 HOH HOH A . V 8 HOH 211 711 479 HOH HOH A . V 8 HOH 212 712 481 HOH HOH A . V 8 HOH 213 713 488 HOH HOH A . V 8 HOH 214 714 489 HOH HOH A . V 8 HOH 215 715 490 HOH HOH A . V 8 HOH 216 716 493 HOH HOH A . V 8 HOH 217 717 495 HOH HOH A . V 8 HOH 218 718 497 HOH HOH A . V 8 HOH 219 719 498 HOH HOH A . V 8 HOH 220 720 501 HOH HOH A . V 8 HOH 221 721 503 HOH HOH A . V 8 HOH 222 722 505 HOH HOH A . V 8 HOH 223 723 506 HOH HOH A . V 8 HOH 224 724 509 HOH HOH A . V 8 HOH 225 725 510 HOH HOH A . V 8 HOH 226 726 514 HOH HOH A . V 8 HOH 227 727 516 HOH HOH A . V 8 HOH 228 728 517 HOH HOH A . V 8 HOH 229 729 520 HOH HOH A . V 8 HOH 230 730 521 HOH HOH A . V 8 HOH 231 731 529 HOH HOH A . V 8 HOH 232 732 532 HOH HOH A . V 8 HOH 233 733 535 HOH HOH A . V 8 HOH 234 734 537 HOH HOH A . V 8 HOH 235 735 538 HOH HOH A . V 8 HOH 236 736 539 HOH HOH A . V 8 HOH 237 737 541 HOH HOH A . V 8 HOH 238 738 542 HOH HOH A . V 8 HOH 239 739 543 HOH HOH A . V 8 HOH 240 740 544 HOH HOH A . V 8 HOH 241 741 548 HOH HOH A . V 8 HOH 242 742 549 HOH HOH A . V 8 HOH 243 743 550 HOH HOH A . V 8 HOH 244 744 551 HOH HOH A . V 8 HOH 245 745 552 HOH HOH A . V 8 HOH 246 746 553 HOH HOH A . V 8 HOH 247 747 554 HOH HOH A . V 8 HOH 248 748 555 HOH HOH A . V 8 HOH 249 749 557 HOH HOH A . V 8 HOH 250 750 558 HOH HOH A . V 8 HOH 251 751 559 HOH HOH A . V 8 HOH 252 752 561 HOH HOH A . V 8 HOH 253 753 562 HOH HOH A . V 8 HOH 254 754 565 HOH HOH A . V 8 HOH 255 755 574 HOH HOH A . V 8 HOH 256 756 575 HOH HOH A . V 8 HOH 257 757 576 HOH HOH A . V 8 HOH 258 758 577 HOH HOH A . V 8 HOH 259 759 578 HOH HOH A . V 8 HOH 260 760 579 HOH HOH A . V 8 HOH 261 761 582 HOH HOH A . V 8 HOH 262 762 585 HOH HOH A . V 8 HOH 263 763 586 HOH HOH A . V 8 HOH 264 764 588 HOH HOH A . V 8 HOH 265 765 589 HOH HOH A . V 8 HOH 266 766 591 HOH HOH A . V 8 HOH 267 767 594 HOH HOH A . V 8 HOH 268 768 598 HOH HOH A . V 8 HOH 269 769 600 HOH HOH A . V 8 HOH 270 770 601 HOH HOH A . V 8 HOH 271 771 603 HOH HOH A . V 8 HOH 272 772 606 HOH HOH A . V 8 HOH 273 773 609 HOH HOH A . V 8 HOH 274 774 611 HOH HOH A . V 8 HOH 275 775 612 HOH HOH A . V 8 HOH 276 776 613 HOH HOH A . V 8 HOH 277 777 614 HOH HOH A . V 8 HOH 278 778 616 HOH HOH A . V 8 HOH 279 779 617 HOH HOH A . V 8 HOH 280 780 618 HOH HOH A . V 8 HOH 281 781 621 HOH HOH A . V 8 HOH 282 782 623 HOH HOH A . V 8 HOH 283 783 627 HOH HOH A . V 8 HOH 284 784 630 HOH HOH A . V 8 HOH 285 785 632 HOH HOH A . V 8 HOH 286 786 636 HOH HOH A . V 8 HOH 287 787 637 HOH HOH A . V 8 HOH 288 788 639 HOH HOH A . V 8 HOH 289 789 641 HOH HOH A . V 8 HOH 290 790 642 HOH HOH A . V 8 HOH 291 791 646 HOH HOH A . V 8 HOH 292 792 651 HOH HOH A . V 8 HOH 293 793 653 HOH HOH A . V 8 HOH 294 794 654 HOH HOH A . V 8 HOH 295 795 655 HOH HOH A . V 8 HOH 296 796 659 HOH HOH A . V 8 HOH 297 797 660 HOH HOH A . V 8 HOH 298 798 661 HOH HOH A . V 8 HOH 299 799 662 HOH HOH A . V 8 HOH 300 800 663 HOH HOH A . V 8 HOH 301 801 665 HOH HOH A . V 8 HOH 302 802 669 HOH HOH A . V 8 HOH 303 803 674 HOH HOH A . V 8 HOH 304 804 676 HOH HOH A . V 8 HOH 305 805 677 HOH HOH A . V 8 HOH 306 806 682 HOH HOH A . V 8 HOH 307 807 683 HOH HOH A . V 8 HOH 308 808 684 HOH HOH A . V 8 HOH 309 809 686 HOH HOH A . V 8 HOH 310 810 688 HOH HOH A . V 8 HOH 311 811 690 HOH HOH A . V 8 HOH 312 812 695 HOH HOH A . V 8 HOH 313 813 697 HOH HOH A . V 8 HOH 314 814 699 HOH HOH A . V 8 HOH 315 815 700 HOH HOH A . V 8 HOH 316 816 702 HOH HOH A . V 8 HOH 317 817 704 HOH HOH A . V 8 HOH 318 818 706 HOH HOH A . V 8 HOH 319 819 707 HOH HOH A . V 8 HOH 320 820 708 HOH HOH A . V 8 HOH 321 821 711 HOH HOH A . V 8 HOH 322 822 712 HOH HOH A . V 8 HOH 323 823 713 HOH HOH A . V 8 HOH 324 824 714 HOH HOH A . V 8 HOH 325 825 721 HOH HOH A . V 8 HOH 326 826 723 HOH HOH A . V 8 HOH 327 827 725 HOH HOH A . V 8 HOH 328 828 726 HOH HOH A . V 8 HOH 329 829 728 HOH HOH A . V 8 HOH 330 830 730 HOH HOH A . V 8 HOH 331 831 735 HOH HOH A . V 8 HOH 332 832 737 HOH HOH A . V 8 HOH 333 833 740 HOH HOH A . V 8 HOH 334 834 741 HOH HOH A . V 8 HOH 335 835 747 HOH HOH A . V 8 HOH 336 836 748 HOH HOH A . V 8 HOH 337 837 751 HOH HOH A . V 8 HOH 338 838 752 HOH HOH A . V 8 HOH 339 839 753 HOH HOH A . V 8 HOH 340 840 755 HOH HOH A . V 8 HOH 341 841 756 HOH HOH A . V 8 HOH 342 842 759 HOH HOH A . V 8 HOH 343 843 760 HOH HOH A . V 8 HOH 344 844 763 HOH HOH A . V 8 HOH 345 845 780 HOH HOH A . V 8 HOH 346 846 795 HOH HOH A . V 8 HOH 347 847 798 HOH HOH A . V 8 HOH 348 848 802 HOH HOH A . V 8 HOH 349 849 803 HOH HOH A . V 8 HOH 350 850 806 HOH HOH A . V 8 HOH 351 851 807 HOH HOH A . V 8 HOH 352 852 811 HOH HOH A . V 8 HOH 353 853 812 HOH HOH A . V 8 HOH 354 854 813 HOH HOH A . V 8 HOH 355 855 825 HOH HOH A . V 8 HOH 356 856 830 HOH HOH A . V 8 HOH 357 857 833 HOH HOH A . V 8 HOH 358 858 835 HOH HOH A . V 8 HOH 359 859 837 HOH HOH A . V 8 HOH 360 860 838 HOH HOH A . V 8 HOH 361 861 839 HOH HOH A . V 8 HOH 362 862 840 HOH HOH A . V 8 HOH 363 863 843 HOH HOH A . V 8 HOH 364 864 845 HOH HOH A . V 8 HOH 365 865 846 HOH HOH A . V 8 HOH 366 866 848 HOH HOH A . V 8 HOH 367 867 849 HOH HOH A . V 8 HOH 368 868 850 HOH HOH A . V 8 HOH 369 869 854 HOH HOH A . V 8 HOH 370 870 858 HOH HOH A . V 8 HOH 371 871 862 HOH HOH A . V 8 HOH 372 872 863 HOH HOH A . V 8 HOH 373 873 864 HOH HOH A . V 8 HOH 374 874 865 HOH HOH A . V 8 HOH 375 875 866 HOH HOH A . V 8 HOH 376 876 876 HOH HOH A . V 8 HOH 377 877 878 HOH HOH A . V 8 HOH 378 878 879 HOH HOH A . V 8 HOH 379 879 883 HOH HOH A . V 8 HOH 380 880 886 HOH HOH A . V 8 HOH 381 881 887 HOH HOH A . V 8 HOH 382 882 889 HOH HOH A . V 8 HOH 383 883 892 HOH HOH A . V 8 HOH 384 884 894 HOH HOH A . V 8 HOH 385 885 896 HOH HOH A . V 8 HOH 386 886 898 HOH HOH A . V 8 HOH 387 887 899 HOH HOH A . V 8 HOH 388 888 901 HOH HOH A . V 8 HOH 389 889 902 HOH HOH A . V 8 HOH 390 890 903 HOH HOH A . V 8 HOH 391 891 905 HOH HOH A . V 8 HOH 392 892 907 HOH HOH A . V 8 HOH 393 893 908 HOH HOH A . V 8 HOH 394 894 910 HOH HOH A . V 8 HOH 395 895 911 HOH HOH A . V 8 HOH 396 896 912 HOH HOH A . V 8 HOH 397 897 916 HOH HOH A . V 8 HOH 398 898 919 HOH HOH A . V 8 HOH 399 899 920 HOH HOH A . V 8 HOH 400 900 933 HOH HOH A . V 8 HOH 401 901 934 HOH HOH A . V 8 HOH 402 902 937 HOH HOH A . V 8 HOH 403 903 938 HOH HOH A . V 8 HOH 404 904 939 HOH HOH A . V 8 HOH 405 905 943 HOH HOH A . V 8 HOH 406 906 945 HOH HOH A . V 8 HOH 407 907 949 HOH HOH A . V 8 HOH 408 908 951 HOH HOH A . V 8 HOH 409 909 955 HOH HOH A . V 8 HOH 410 910 956 HOH HOH A . V 8 HOH 411 911 959 HOH HOH A . V 8 HOH 412 912 962 HOH HOH A . V 8 HOH 413 913 963 HOH HOH A . V 8 HOH 414 914 964 HOH HOH A . V 8 HOH 415 915 968 HOH HOH A . V 8 HOH 416 916 970 HOH HOH A . V 8 HOH 417 917 972 HOH HOH A . V 8 HOH 418 918 975 HOH HOH A . V 8 HOH 419 919 976 HOH HOH A . V 8 HOH 420 920 978 HOH HOH A . V 8 HOH 421 921 979 HOH HOH A . V 8 HOH 422 922 980 HOH HOH A . V 8 HOH 423 923 981 HOH HOH A . V 8 HOH 424 924 983 HOH HOH A . V 8 HOH 425 925 987 HOH HOH A . V 8 HOH 426 926 989 HOH HOH A . V 8 HOH 427 927 993 HOH HOH A . V 8 HOH 428 928 994 HOH HOH A . V 8 HOH 429 929 995 HOH HOH A . V 8 HOH 430 930 999 HOH HOH A . V 8 HOH 431 931 1003 HOH HOH A . V 8 HOH 432 932 1004 HOH HOH A . V 8 HOH 433 933 1007 HOH HOH A . V 8 HOH 434 934 1012 HOH HOH A . V 8 HOH 435 935 1013 HOH HOH A . V 8 HOH 436 936 1014 HOH HOH A . V 8 HOH 437 937 1015 HOH HOH A . V 8 HOH 438 938 1020 HOH HOH A . V 8 HOH 439 939 1021 HOH HOH A . V 8 HOH 440 940 1030 HOH HOH A . V 8 HOH 441 941 1035 HOH HOH A . V 8 HOH 442 942 1042 HOH HOH A . V 8 HOH 443 943 1044 HOH HOH A . V 8 HOH 444 944 1046 HOH HOH A . V 8 HOH 445 945 1047 HOH HOH A . V 8 HOH 446 946 1048 HOH HOH A . V 8 HOH 447 947 1054 HOH HOH A . V 8 HOH 448 948 1057 HOH HOH A . V 8 HOH 449 949 1058 HOH HOH A . V 8 HOH 450 950 1059 HOH HOH A . V 8 HOH 451 951 1061 HOH HOH A . V 8 HOH 452 952 1062 HOH HOH A . V 8 HOH 453 953 1063 HOH HOH A . V 8 HOH 454 954 1069 HOH HOH A . V 8 HOH 455 955 1070 HOH HOH A . V 8 HOH 456 956 1071 HOH HOH A . V 8 HOH 457 957 1072 HOH HOH A . V 8 HOH 458 958 1074 HOH HOH A . V 8 HOH 459 959 1082 HOH HOH A . V 8 HOH 460 960 1083 HOH HOH A . V 8 HOH 461 961 1089 HOH HOH A . V 8 HOH 462 962 1090 HOH HOH A . V 8 HOH 463 963 1093 HOH HOH A . V 8 HOH 464 964 1096 HOH HOH A . V 8 HOH 465 965 1098 HOH HOH A . V 8 HOH 466 966 1099 HOH HOH A . V 8 HOH 467 967 1102 HOH HOH A . V 8 HOH 468 968 1103 HOH HOH A . V 8 HOH 469 969 1104 HOH HOH A . V 8 HOH 470 970 1105 HOH HOH A . V 8 HOH 471 971 1106 HOH HOH A . V 8 HOH 472 972 1107 HOH HOH A . V 8 HOH 473 973 1111 HOH HOH A . V 8 HOH 474 974 1112 HOH HOH A . W 8 HOH 1 301 2 HOH HOH B . W 8 HOH 2 302 5 HOH HOH B . W 8 HOH 3 303 12 HOH HOH B . W 8 HOH 4 304 23 HOH HOH B . W 8 HOH 5 305 26 HOH HOH B . W 8 HOH 6 306 27 HOH HOH B . W 8 HOH 7 307 30 HOH HOH B . W 8 HOH 8 308 31 HOH HOH B . W 8 HOH 9 309 35 HOH HOH B . W 8 HOH 10 310 40 HOH HOH B . W 8 HOH 11 311 46 HOH HOH B . W 8 HOH 12 312 53 HOH HOH B . W 8 HOH 13 313 54 HOH HOH B . W 8 HOH 14 314 57 HOH HOH B . W 8 HOH 15 315 58 HOH HOH B . W 8 HOH 16 316 66 HOH HOH B . W 8 HOH 17 317 67 HOH HOH B . W 8 HOH 18 318 68 HOH HOH B . W 8 HOH 19 319 70 HOH HOH B . W 8 HOH 20 320 76 HOH HOH B . W 8 HOH 21 321 78 HOH HOH B . W 8 HOH 22 322 81 HOH HOH B . W 8 HOH 23 323 83 HOH HOH B . W 8 HOH 24 324 84 HOH HOH B . W 8 HOH 25 325 85 HOH HOH B . W 8 HOH 26 326 87 HOH HOH B . W 8 HOH 27 327 88 HOH HOH B . W 8 HOH 28 328 97 HOH HOH B . W 8 HOH 29 329 101 HOH HOH B . W 8 HOH 30 330 102 HOH HOH B . W 8 HOH 31 331 105 HOH HOH B . W 8 HOH 32 332 107 HOH HOH B . W 8 HOH 33 333 108 HOH HOH B . W 8 HOH 34 334 111 HOH HOH B . W 8 HOH 35 335 122 HOH HOH B . W 8 HOH 36 336 126 HOH HOH B . W 8 HOH 37 337 127 HOH HOH B . W 8 HOH 38 338 128 HOH HOH B . W 8 HOH 39 339 144 HOH HOH B . W 8 HOH 40 340 145 HOH HOH B . W 8 HOH 41 341 146 HOH HOH B . W 8 HOH 42 342 149 HOH HOH B . W 8 HOH 43 343 153 HOH HOH B . W 8 HOH 44 344 163 HOH HOH B . W 8 HOH 45 345 175 HOH HOH B . W 8 HOH 46 346 178 HOH HOH B . W 8 HOH 47 347 186 HOH HOH B . W 8 HOH 48 348 187 HOH HOH B . W 8 HOH 49 349 192 HOH HOH B . W 8 HOH 50 350 202 HOH HOH B . W 8 HOH 51 351 203 HOH HOH B . W 8 HOH 52 352 208 HOH HOH B . W 8 HOH 53 353 210 HOH HOH B . W 8 HOH 54 354 212 HOH HOH B . W 8 HOH 55 355 220 HOH HOH B . W 8 HOH 56 356 230 HOH HOH B . W 8 HOH 57 357 231 HOH HOH B . W 8 HOH 58 358 233 HOH HOH B . W 8 HOH 59 359 237 HOH HOH B . W 8 HOH 60 360 238 HOH HOH B . W 8 HOH 61 361 239 HOH HOH B . W 8 HOH 62 362 247 HOH HOH B . W 8 HOH 63 363 251 HOH HOH B . W 8 HOH 64 364 252 HOH HOH B . W 8 HOH 65 365 257 HOH HOH B . W 8 HOH 66 366 263 HOH HOH B . W 8 HOH 67 367 264 HOH HOH B . W 8 HOH 68 368 269 HOH HOH B . W 8 HOH 69 369 279 HOH HOH B . W 8 HOH 70 370 290 HOH HOH B . W 8 HOH 71 371 301 HOH HOH B . W 8 HOH 72 372 304 HOH HOH B . W 8 HOH 73 373 308 HOH HOH B . W 8 HOH 74 374 331 HOH HOH B . W 8 HOH 75 375 332 HOH HOH B . W 8 HOH 76 376 342 HOH HOH B . W 8 HOH 77 377 343 HOH HOH B . W 8 HOH 78 378 348 HOH HOH B . W 8 HOH 79 379 350 HOH HOH B . W 8 HOH 80 380 352 HOH HOH B . W 8 HOH 81 381 353 HOH HOH B . W 8 HOH 82 382 354 HOH HOH B . W 8 HOH 83 383 361 HOH HOH B . W 8 HOH 84 384 362 HOH HOH B . W 8 HOH 85 385 363 HOH HOH B . W 8 HOH 86 386 370 HOH HOH B . W 8 HOH 87 387 373 HOH HOH B . W 8 HOH 88 388 376 HOH HOH B . W 8 HOH 89 389 381 HOH HOH B . W 8 HOH 90 390 382 HOH HOH B . W 8 HOH 91 391 388 HOH HOH B . W 8 HOH 92 392 391 HOH HOH B . W 8 HOH 93 393 394 HOH HOH B . W 8 HOH 94 394 396 HOH HOH B . W 8 HOH 95 395 399 HOH HOH B . W 8 HOH 96 396 407 HOH HOH B . W 8 HOH 97 397 408 HOH HOH B . W 8 HOH 98 398 411 HOH HOH B . W 8 HOH 99 399 427 HOH HOH B . W 8 HOH 100 400 441 HOH HOH B . W 8 HOH 101 401 444 HOH HOH B . W 8 HOH 102 402 450 HOH HOH B . W 8 HOH 103 403 456 HOH HOH B . W 8 HOH 104 404 460 HOH HOH B . W 8 HOH 105 405 461 HOH HOH B . W 8 HOH 106 406 465 HOH HOH B . W 8 HOH 107 407 470 HOH HOH B . W 8 HOH 108 408 480 HOH HOH B . W 8 HOH 109 409 484 HOH HOH B . W 8 HOH 110 410 485 HOH HOH B . W 8 HOH 111 411 494 HOH HOH B . W 8 HOH 112 412 499 HOH HOH B . W 8 HOH 113 413 502 HOH HOH B . W 8 HOH 114 414 507 HOH HOH B . W 8 HOH 115 415 511 HOH HOH B . W 8 HOH 116 416 512 HOH HOH B . W 8 HOH 117 417 515 HOH HOH B . W 8 HOH 118 418 518 HOH HOH B . W 8 HOH 119 419 530 HOH HOH B . W 8 HOH 120 420 531 HOH HOH B . W 8 HOH 121 421 546 HOH HOH B . W 8 HOH 122 422 547 HOH HOH B . W 8 HOH 123 423 556 HOH HOH B . W 8 HOH 124 424 566 HOH HOH B . W 8 HOH 125 425 571 HOH HOH B . W 8 HOH 126 426 581 HOH HOH B . W 8 HOH 127 427 590 HOH HOH B . W 8 HOH 128 428 592 HOH HOH B . W 8 HOH 129 429 593 HOH HOH B . W 8 HOH 130 430 595 HOH HOH B . W 8 HOH 131 431 602 HOH HOH B . W 8 HOH 132 432 604 HOH HOH B . W 8 HOH 133 433 610 HOH HOH B . W 8 HOH 134 434 628 HOH HOH B . W 8 HOH 135 435 633 HOH HOH B . W 8 HOH 136 436 635 HOH HOH B . W 8 HOH 137 437 643 HOH HOH B . W 8 HOH 138 438 645 HOH HOH B . W 8 HOH 139 439 647 HOH HOH B . W 8 HOH 140 440 648 HOH HOH B . W 8 HOH 141 441 650 HOH HOH B . W 8 HOH 142 442 664 HOH HOH B . W 8 HOH 143 443 668 HOH HOH B . W 8 HOH 144 444 670 HOH HOH B . W 8 HOH 145 445 678 HOH HOH B . W 8 HOH 146 446 681 HOH HOH B . W 8 HOH 147 447 685 HOH HOH B . W 8 HOH 148 448 694 HOH HOH B . W 8 HOH 149 449 696 HOH HOH B . W 8 HOH 150 450 698 HOH HOH B . W 8 HOH 151 451 703 HOH HOH B . W 8 HOH 152 452 705 HOH HOH B . W 8 HOH 153 453 709 HOH HOH B . W 8 HOH 154 454 716 HOH HOH B . W 8 HOH 155 455 729 HOH HOH B . W 8 HOH 156 456 731 HOH HOH B . W 8 HOH 157 457 733 HOH HOH B . W 8 HOH 158 458 754 HOH HOH B . W 8 HOH 159 459 758 HOH HOH B . W 8 HOH 160 460 761 HOH HOH B . W 8 HOH 161 461 762 HOH HOH B . W 8 HOH 162 462 767 HOH HOH B . W 8 HOH 163 463 768 HOH HOH B . W 8 HOH 164 464 769 HOH HOH B . W 8 HOH 165 465 770 HOH HOH B . W 8 HOH 166 466 771 HOH HOH B . W 8 HOH 167 467 773 HOH HOH B . W 8 HOH 168 468 774 HOH HOH B . W 8 HOH 169 469 775 HOH HOH B . W 8 HOH 170 470 776 HOH HOH B . W 8 HOH 171 471 785 HOH HOH B . W 8 HOH 172 472 786 HOH HOH B . W 8 HOH 173 473 787 HOH HOH B . W 8 HOH 174 474 789 HOH HOH B . W 8 HOH 175 475 790 HOH HOH B . W 8 HOH 176 476 791 HOH HOH B . W 8 HOH 177 477 792 HOH HOH B . W 8 HOH 178 478 793 HOH HOH B . W 8 HOH 179 479 800 HOH HOH B . W 8 HOH 180 480 801 HOH HOH B . W 8 HOH 181 481 804 HOH HOH B . W 8 HOH 182 482 808 HOH HOH B . W 8 HOH 183 483 809 HOH HOH B . W 8 HOH 184 484 822 HOH HOH B . W 8 HOH 185 485 824 HOH HOH B . W 8 HOH 186 486 832 HOH HOH B . W 8 HOH 187 487 841 HOH HOH B . W 8 HOH 188 488 844 HOH HOH B . W 8 HOH 189 489 851 HOH HOH B . W 8 HOH 190 490 852 HOH HOH B . W 8 HOH 191 491 853 HOH HOH B . W 8 HOH 192 492 869 HOH HOH B . W 8 HOH 193 493 870 HOH HOH B . W 8 HOH 194 494 871 HOH HOH B . W 8 HOH 195 495 873 HOH HOH B . W 8 HOH 196 496 875 HOH HOH B . W 8 HOH 197 497 877 HOH HOH B . W 8 HOH 198 498 890 HOH HOH B . W 8 HOH 199 499 891 HOH HOH B . W 8 HOH 200 500 904 HOH HOH B . W 8 HOH 201 501 915 HOH HOH B . W 8 HOH 202 502 922 HOH HOH B . W 8 HOH 203 503 926 HOH HOH B . W 8 HOH 204 504 928 HOH HOH B . W 8 HOH 205 505 940 HOH HOH B . W 8 HOH 206 506 946 HOH HOH B . W 8 HOH 207 507 947 HOH HOH B . W 8 HOH 208 508 948 HOH HOH B . W 8 HOH 209 509 952 HOH HOH B . W 8 HOH 210 510 957 HOH HOH B . W 8 HOH 211 511 965 HOH HOH B . W 8 HOH 212 512 969 HOH HOH B . W 8 HOH 213 513 971 HOH HOH B . W 8 HOH 214 514 984 HOH HOH B . W 8 HOH 215 515 985 HOH HOH B . W 8 HOH 216 516 986 HOH HOH B . W 8 HOH 217 517 991 HOH HOH B . W 8 HOH 218 518 997 HOH HOH B . W 8 HOH 219 519 1002 HOH HOH B . W 8 HOH 220 520 1008 HOH HOH B . W 8 HOH 221 521 1010 HOH HOH B . W 8 HOH 222 522 1016 HOH HOH B . W 8 HOH 223 523 1018 HOH HOH B . W 8 HOH 224 524 1019 HOH HOH B . W 8 HOH 225 525 1022 HOH HOH B . W 8 HOH 226 526 1023 HOH HOH B . W 8 HOH 227 527 1025 HOH HOH B . W 8 HOH 228 528 1027 HOH HOH B . W 8 HOH 229 529 1028 HOH HOH B . W 8 HOH 230 530 1029 HOH HOH B . W 8 HOH 231 531 1038 HOH HOH B . W 8 HOH 232 532 1041 HOH HOH B . W 8 HOH 233 533 1055 HOH HOH B . W 8 HOH 234 534 1060 HOH HOH B . W 8 HOH 235 535 1066 HOH HOH B . W 8 HOH 236 536 1068 HOH HOH B . W 8 HOH 237 537 1077 HOH HOH B . W 8 HOH 238 538 1084 HOH HOH B . W 8 HOH 239 539 1092 HOH HOH B . W 8 HOH 240 540 1101 HOH HOH B . W 8 HOH 241 541 1109 HOH HOH B . W 8 HOH 242 542 1110 HOH HOH B . X 8 HOH 1 401 1 HOH HOH H . X 8 HOH 2 402 3 HOH HOH H . X 8 HOH 3 403 10 HOH HOH H . X 8 HOH 4 404 14 HOH HOH H . X 8 HOH 5 405 15 HOH HOH H . X 8 HOH 6 406 16 HOH HOH H . X 8 HOH 7 407 17 HOH HOH H . X 8 HOH 8 408 18 HOH HOH H . X 8 HOH 9 409 22 HOH HOH H . X 8 HOH 10 410 29 HOH HOH H . X 8 HOH 11 411 36 HOH HOH H . X 8 HOH 12 412 38 HOH HOH H . X 8 HOH 13 413 41 HOH HOH H . X 8 HOH 14 414 42 HOH HOH H . X 8 HOH 15 415 45 HOH HOH H . X 8 HOH 16 416 50 HOH HOH H . X 8 HOH 17 417 52 HOH HOH H . X 8 HOH 18 418 55 HOH HOH H . X 8 HOH 19 419 59 HOH HOH H . X 8 HOH 20 420 62 HOH HOH H . X 8 HOH 21 421 69 HOH HOH H . X 8 HOH 22 422 72 HOH HOH H . X 8 HOH 23 423 73 HOH HOH H . X 8 HOH 24 424 74 HOH HOH H . X 8 HOH 25 425 75 HOH HOH H . X 8 HOH 26 426 77 HOH HOH H . X 8 HOH 27 427 82 HOH HOH H . X 8 HOH 28 428 90 HOH HOH H . X 8 HOH 29 429 92 HOH HOH H . X 8 HOH 30 430 93 HOH HOH H . X 8 HOH 31 431 94 HOH HOH H . X 8 HOH 32 432 112 HOH HOH H . X 8 HOH 33 433 113 HOH HOH H . X 8 HOH 34 434 114 HOH HOH H . X 8 HOH 35 435 116 HOH HOH H . X 8 HOH 36 436 117 HOH HOH H . X 8 HOH 37 437 121 HOH HOH H . X 8 HOH 38 438 131 HOH HOH H . X 8 HOH 39 439 134 HOH HOH H . X 8 HOH 40 440 138 HOH HOH H . X 8 HOH 41 441 140 HOH HOH H . X 8 HOH 42 442 141 HOH HOH H . X 8 HOH 43 443 150 HOH HOH H . X 8 HOH 44 444 155 HOH HOH H . X 8 HOH 45 445 158 HOH HOH H . X 8 HOH 46 446 160 HOH HOH H . X 8 HOH 47 447 173 HOH HOH H . X 8 HOH 48 448 174 HOH HOH H . X 8 HOH 49 449 179 HOH HOH H . X 8 HOH 50 450 180 HOH HOH H . X 8 HOH 51 451 181 HOH HOH H . X 8 HOH 52 452 182 HOH HOH H . X 8 HOH 53 453 183 HOH HOH H . X 8 HOH 54 454 197 HOH HOH H . X 8 HOH 55 455 199 HOH HOH H . X 8 HOH 56 456 206 HOH HOH H . X 8 HOH 57 457 209 HOH HOH H . X 8 HOH 58 458 211 HOH HOH H . X 8 HOH 59 459 232 HOH HOH H . X 8 HOH 60 460 234 HOH HOH H . X 8 HOH 61 461 236 HOH HOH H . X 8 HOH 62 462 240 HOH HOH H . X 8 HOH 63 463 242 HOH HOH H . X 8 HOH 64 464 246 HOH HOH H . X 8 HOH 65 465 253 HOH HOH H . X 8 HOH 66 466 255 HOH HOH H . X 8 HOH 67 467 256 HOH HOH H . X 8 HOH 68 468 260 HOH HOH H . X 8 HOH 69 469 265 HOH HOH H . X 8 HOH 70 470 270 HOH HOH H . X 8 HOH 71 471 271 HOH HOH H . X 8 HOH 72 472 274 HOH HOH H . X 8 HOH 73 473 275 HOH HOH H . X 8 HOH 74 474 277 HOH HOH H . X 8 HOH 75 475 280 HOH HOH H . X 8 HOH 76 476 285 HOH HOH H . X 8 HOH 77 477 289 HOH HOH H . X 8 HOH 78 478 306 HOH HOH H . X 8 HOH 79 479 312 HOH HOH H . X 8 HOH 80 480 317 HOH HOH H . X 8 HOH 81 481 318 HOH HOH H . X 8 HOH 82 482 325 HOH HOH H . X 8 HOH 83 483 326 HOH HOH H . X 8 HOH 84 484 327 HOH HOH H . X 8 HOH 85 485 328 HOH HOH H . X 8 HOH 86 486 338 HOH HOH H . X 8 HOH 87 487 345 HOH HOH H . X 8 HOH 88 488 349 HOH HOH H . X 8 HOH 89 489 358 HOH HOH H . X 8 HOH 90 490 364 HOH HOH H . X 8 HOH 91 491 367 HOH HOH H . X 8 HOH 92 492 372 HOH HOH H . X 8 HOH 93 493 378 HOH HOH H . X 8 HOH 94 494 389 HOH HOH H . X 8 HOH 95 495 392 HOH HOH H . X 8 HOH 96 496 397 HOH HOH H . X 8 HOH 97 497 401 HOH HOH H . X 8 HOH 98 498 409 HOH HOH H . X 8 HOH 99 499 421 HOH HOH H . X 8 HOH 100 500 424 HOH HOH H . X 8 HOH 101 501 425 HOH HOH H . X 8 HOH 102 502 433 HOH HOH H . X 8 HOH 103 503 436 HOH HOH H . X 8 HOH 104 504 437 HOH HOH H . X 8 HOH 105 505 438 HOH HOH H . X 8 HOH 106 506 442 HOH HOH H . X 8 HOH 107 507 445 HOH HOH H . X 8 HOH 108 508 454 HOH HOH H . X 8 HOH 109 509 457 HOH HOH H . X 8 HOH 110 510 458 HOH HOH H . X 8 HOH 111 511 462 HOH HOH H . X 8 HOH 112 512 468 HOH HOH H . X 8 HOH 113 513 477 HOH HOH H . X 8 HOH 114 514 478 HOH HOH H . X 8 HOH 115 515 482 HOH HOH H . X 8 HOH 116 516 483 HOH HOH H . X 8 HOH 117 517 504 HOH HOH H . X 8 HOH 118 518 508 HOH HOH H . X 8 HOH 119 519 519 HOH HOH H . X 8 HOH 120 520 524 HOH HOH H . X 8 HOH 121 521 525 HOH HOH H . X 8 HOH 122 522 526 HOH HOH H . X 8 HOH 123 523 533 HOH HOH H . X 8 HOH 124 524 534 HOH HOH H . X 8 HOH 125 525 536 HOH HOH H . X 8 HOH 126 526 540 HOH HOH H . X 8 HOH 127 527 569 HOH HOH H . X 8 HOH 128 528 570 HOH HOH H . X 8 HOH 129 529 580 HOH HOH H . X 8 HOH 130 530 584 HOH HOH H . X 8 HOH 131 531 587 HOH HOH H . X 8 HOH 132 532 596 HOH HOH H . X 8 HOH 133 533 599 HOH HOH H . X 8 HOH 134 534 607 HOH HOH H . X 8 HOH 135 535 608 HOH HOH H . X 8 HOH 136 536 615 HOH HOH H . X 8 HOH 137 537 619 HOH HOH H . X 8 HOH 138 538 620 HOH HOH H . X 8 HOH 139 539 624 HOH HOH H . X 8 HOH 140 540 626 HOH HOH H . X 8 HOH 141 541 631 HOH HOH H . X 8 HOH 142 542 644 HOH HOH H . X 8 HOH 143 543 656 HOH HOH H . X 8 HOH 144 544 667 HOH HOH H . X 8 HOH 145 545 671 HOH HOH H . X 8 HOH 146 546 672 HOH HOH H . X 8 HOH 147 547 673 HOH HOH H . X 8 HOH 148 548 675 HOH HOH H . X 8 HOH 149 549 689 HOH HOH H . X 8 HOH 150 550 693 HOH HOH H . X 8 HOH 151 551 710 HOH HOH H . X 8 HOH 152 552 715 HOH HOH H . X 8 HOH 153 553 717 HOH HOH H . X 8 HOH 154 554 718 HOH HOH H . X 8 HOH 155 555 719 HOH HOH H . X 8 HOH 156 556 720 HOH HOH H . X 8 HOH 157 557 722 HOH HOH H . X 8 HOH 158 558 724 HOH HOH H . X 8 HOH 159 559 727 HOH HOH H . X 8 HOH 160 560 732 HOH HOH H . X 8 HOH 161 561 734 HOH HOH H . X 8 HOH 162 562 736 HOH HOH H . X 8 HOH 163 563 739 HOH HOH H . X 8 HOH 164 564 743 HOH HOH H . X 8 HOH 165 565 744 HOH HOH H . X 8 HOH 166 566 750 HOH HOH H . X 8 HOH 167 567 757 HOH HOH H . X 8 HOH 168 568 764 HOH HOH H . X 8 HOH 169 569 765 HOH HOH H . X 8 HOH 170 570 766 HOH HOH H . X 8 HOH 171 571 772 HOH HOH H . X 8 HOH 172 572 778 HOH HOH H . X 8 HOH 173 573 781 HOH HOH H . X 8 HOH 174 574 782 HOH HOH H . X 8 HOH 175 575 784 HOH HOH H . X 8 HOH 176 576 788 HOH HOH H . X 8 HOH 177 577 805 HOH HOH H . X 8 HOH 178 578 814 HOH HOH H . X 8 HOH 179 579 816 HOH HOH H . X 8 HOH 180 580 817 HOH HOH H . X 8 HOH 181 581 821 HOH HOH H . X 8 HOH 182 582 823 HOH HOH H . X 8 HOH 183 583 826 HOH HOH H . X 8 HOH 184 584 827 HOH HOH H . X 8 HOH 185 585 829 HOH HOH H . X 8 HOH 186 586 831 HOH HOH H . X 8 HOH 187 587 834 HOH HOH H . X 8 HOH 188 588 842 HOH HOH H . X 8 HOH 189 589 856 HOH HOH H . X 8 HOH 190 590 860 HOH HOH H . X 8 HOH 191 591 868 HOH HOH H . X 8 HOH 192 592 872 HOH HOH H . X 8 HOH 193 593 874 HOH HOH H . X 8 HOH 194 594 881 HOH HOH H . X 8 HOH 195 595 882 HOH HOH H . X 8 HOH 196 596 884 HOH HOH H . X 8 HOH 197 597 888 HOH HOH H . X 8 HOH 198 598 893 HOH HOH H . X 8 HOH 199 599 895 HOH HOH H . X 8 HOH 200 600 900 HOH HOH H . X 8 HOH 201 601 909 HOH HOH H . X 8 HOH 202 602 913 HOH HOH H . X 8 HOH 203 603 914 HOH HOH H . X 8 HOH 204 604 917 HOH HOH H . X 8 HOH 205 605 918 HOH HOH H . X 8 HOH 206 606 923 HOH HOH H . X 8 HOH 207 607 927 HOH HOH H . X 8 HOH 208 608 929 HOH HOH H . X 8 HOH 209 609 930 HOH HOH H . X 8 HOH 210 610 932 HOH HOH H . X 8 HOH 211 611 936 HOH HOH H . X 8 HOH 212 612 944 HOH HOH H . X 8 HOH 213 613 950 HOH HOH H . X 8 HOH 214 614 953 HOH HOH H . X 8 HOH 215 615 960 HOH HOH H . X 8 HOH 216 616 961 HOH HOH H . X 8 HOH 217 617 966 HOH HOH H . X 8 HOH 218 618 967 HOH HOH H . X 8 HOH 219 619 973 HOH HOH H . X 8 HOH 220 620 977 HOH HOH H . X 8 HOH 221 621 988 HOH HOH H . X 8 HOH 222 622 996 HOH HOH H . X 8 HOH 223 623 1000 HOH HOH H . X 8 HOH 224 624 1005 HOH HOH H . X 8 HOH 225 625 1024 HOH HOH H . X 8 HOH 226 626 1026 HOH HOH H . X 8 HOH 227 627 1032 HOH HOH H . X 8 HOH 228 628 1037 HOH HOH H . X 8 HOH 229 629 1039 HOH HOH H . X 8 HOH 230 630 1040 HOH HOH H . X 8 HOH 231 631 1043 HOH HOH H . X 8 HOH 232 632 1053 HOH HOH H . X 8 HOH 233 633 1065 HOH HOH H . X 8 HOH 234 634 1076 HOH HOH H . X 8 HOH 235 635 1079 HOH HOH H . X 8 HOH 236 636 1085 HOH HOH H . X 8 HOH 237 637 1086 HOH HOH H . X 8 HOH 238 638 1088 HOH HOH H . X 8 HOH 239 639 1097 HOH HOH H . Y 8 HOH 1 301 20 HOH HOH L . Y 8 HOH 2 302 33 HOH HOH L . Y 8 HOH 3 303 49 HOH HOH L . Y 8 HOH 4 304 71 HOH HOH L . Y 8 HOH 5 305 123 HOH HOH L . Y 8 HOH 6 306 143 HOH HOH L . Y 8 HOH 7 307 147 HOH HOH L . Y 8 HOH 8 308 152 HOH HOH L . Y 8 HOH 9 309 157 HOH HOH L . Y 8 HOH 10 310 162 HOH HOH L . Y 8 HOH 11 311 165 HOH HOH L . Y 8 HOH 12 312 171 HOH HOH L . Y 8 HOH 13 313 189 HOH HOH L . Y 8 HOH 14 314 200 HOH HOH L . Y 8 HOH 15 315 213 HOH HOH L . Y 8 HOH 16 316 215 HOH HOH L . Y 8 HOH 17 317 216 HOH HOH L . Y 8 HOH 18 318 219 HOH HOH L . Y 8 HOH 19 319 222 HOH HOH L . Y 8 HOH 20 320 267 HOH HOH L . Y 8 HOH 21 321 286 HOH HOH L . Y 8 HOH 22 322 297 HOH HOH L . Y 8 HOH 23 323 307 HOH HOH L . Y 8 HOH 24 324 310 HOH HOH L . Y 8 HOH 25 325 311 HOH HOH L . Y 8 HOH 26 326 313 HOH HOH L . Y 8 HOH 27 327 314 HOH HOH L . Y 8 HOH 28 328 321 HOH HOH L . Y 8 HOH 29 329 322 HOH HOH L . Y 8 HOH 30 330 324 HOH HOH L . Y 8 HOH 31 331 333 HOH HOH L . Y 8 HOH 32 332 355 HOH HOH L . Y 8 HOH 33 333 356 HOH HOH L . Y 8 HOH 34 334 357 HOH HOH L . Y 8 HOH 35 335 360 HOH HOH L . Y 8 HOH 36 336 366 HOH HOH L . Y 8 HOH 37 337 369 HOH HOH L . Y 8 HOH 38 338 402 HOH HOH L . Y 8 HOH 39 339 410 HOH HOH L . Y 8 HOH 40 340 413 HOH HOH L . Y 8 HOH 41 341 419 HOH HOH L . Y 8 HOH 42 342 431 HOH HOH L . Y 8 HOH 43 343 439 HOH HOH L . Y 8 HOH 44 344 452 HOH HOH L . Y 8 HOH 45 345 469 HOH HOH L . Y 8 HOH 46 346 471 HOH HOH L . Y 8 HOH 47 347 486 HOH HOH L . Y 8 HOH 48 348 487 HOH HOH L . Y 8 HOH 49 349 492 HOH HOH L . Y 8 HOH 50 350 496 HOH HOH L . Y 8 HOH 51 351 500 HOH HOH L . Y 8 HOH 52 352 513 HOH HOH L . Y 8 HOH 53 353 522 HOH HOH L . Y 8 HOH 54 354 523 HOH HOH L . Y 8 HOH 55 355 527 HOH HOH L . Y 8 HOH 56 356 528 HOH HOH L . Y 8 HOH 57 357 545 HOH HOH L . Y 8 HOH 58 358 560 HOH HOH L . Y 8 HOH 59 359 563 HOH HOH L . Y 8 HOH 60 360 564 HOH HOH L . Y 8 HOH 61 361 567 HOH HOH L . Y 8 HOH 62 362 568 HOH HOH L . Y 8 HOH 63 363 572 HOH HOH L . Y 8 HOH 64 364 573 HOH HOH L . Y 8 HOH 65 365 583 HOH HOH L . Y 8 HOH 66 366 597 HOH HOH L . Y 8 HOH 67 367 605 HOH HOH L . Y 8 HOH 68 368 625 HOH HOH L . Y 8 HOH 69 369 629 HOH HOH L . Y 8 HOH 70 370 638 HOH HOH L . Y 8 HOH 71 371 640 HOH HOH L . Y 8 HOH 72 372 649 HOH HOH L . Y 8 HOH 73 373 652 HOH HOH L . Y 8 HOH 74 374 657 HOH HOH L . Y 8 HOH 75 375 666 HOH HOH L . Y 8 HOH 76 376 680 HOH HOH L . Y 8 HOH 77 377 687 HOH HOH L . Y 8 HOH 78 378 691 HOH HOH L . Y 8 HOH 79 379 692 HOH HOH L . Y 8 HOH 80 380 701 HOH HOH L . Y 8 HOH 81 381 738 HOH HOH L . Y 8 HOH 82 382 742 HOH HOH L . Y 8 HOH 83 383 745 HOH HOH L . Y 8 HOH 84 384 746 HOH HOH L . Y 8 HOH 85 385 749 HOH HOH L . Y 8 HOH 86 386 777 HOH HOH L . Y 8 HOH 87 387 794 HOH HOH L . Y 8 HOH 88 388 796 HOH HOH L . Y 8 HOH 89 389 797 HOH HOH L . Y 8 HOH 90 390 799 HOH HOH L . Y 8 HOH 91 391 815 HOH HOH L . Y 8 HOH 92 392 818 HOH HOH L . Y 8 HOH 93 393 819 HOH HOH L . Y 8 HOH 94 394 820 HOH HOH L . Y 8 HOH 95 395 847 HOH HOH L . Y 8 HOH 96 396 855 HOH HOH L . Y 8 HOH 97 397 859 HOH HOH L . Y 8 HOH 98 398 861 HOH HOH L . Y 8 HOH 99 399 867 HOH HOH L . Y 8 HOH 100 400 880 HOH HOH L . Y 8 HOH 101 401 885 HOH HOH L . Y 8 HOH 102 402 897 HOH HOH L . Y 8 HOH 103 403 906 HOH HOH L . Y 8 HOH 104 404 921 HOH HOH L . Y 8 HOH 105 405 924 HOH HOH L . Y 8 HOH 106 406 931 HOH HOH L . Y 8 HOH 107 407 935 HOH HOH L . Y 8 HOH 108 408 942 HOH HOH L . Y 8 HOH 109 409 954 HOH HOH L . Y 8 HOH 110 410 974 HOH HOH L . Y 8 HOH 111 411 990 HOH HOH L . Y 8 HOH 112 412 992 HOH HOH L . Y 8 HOH 113 413 1001 HOH HOH L . Y 8 HOH 114 414 1006 HOH HOH L . Y 8 HOH 115 415 1009 HOH HOH L . Y 8 HOH 116 416 1011 HOH HOH L . Y 8 HOH 117 417 1017 HOH HOH L . Y 8 HOH 118 418 1031 HOH HOH L . Y 8 HOH 119 419 1034 HOH HOH L . Y 8 HOH 120 420 1049 HOH HOH L . Y 8 HOH 121 421 1051 HOH HOH L . Y 8 HOH 122 422 1052 HOH HOH L . Y 8 HOH 123 423 1056 HOH HOH L . Y 8 HOH 124 424 1064 HOH HOH L . Y 8 HOH 125 425 1067 HOH HOH L . Y 8 HOH 126 426 1073 HOH HOH L . Y 8 HOH 127 427 1075 HOH HOH L . Y 8 HOH 128 428 1078 HOH HOH L . Y 8 HOH 129 429 1080 HOH HOH L . Y 8 HOH 130 430 1081 HOH HOH L . Y 8 HOH 131 431 1087 HOH HOH L . Y 8 HOH 132 432 1091 HOH HOH L . Y 8 HOH 133 433 1094 HOH HOH L . Y 8 HOH 134 434 1095 HOH HOH L . Y 8 HOH 135 435 1100 HOH HOH L . Y 8 HOH 136 436 1108 HOH HOH L . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 B ASN 154 B ASN 154 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 169 A ASN 169 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 15 A ASN 21 ? ASN 'GLYCOSYLATION SITE' 4 A ASN 27 A ASN 33 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details dodecameric _pdbx_struct_assembly.oligomeric_count 12 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1,2,3 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y # loop_ _pdbx_struct_oper_list.id _pdbx_struct_oper_list.type _pdbx_struct_oper_list.name _pdbx_struct_oper_list.symmetry_operation _pdbx_struct_oper_list.matrix[1][1] _pdbx_struct_oper_list.matrix[1][2] _pdbx_struct_oper_list.matrix[1][3] _pdbx_struct_oper_list.vector[1] _pdbx_struct_oper_list.matrix[2][1] _pdbx_struct_oper_list.matrix[2][2] _pdbx_struct_oper_list.matrix[2][3] _pdbx_struct_oper_list.vector[2] _pdbx_struct_oper_list.matrix[3][1] _pdbx_struct_oper_list.matrix[3][2] _pdbx_struct_oper_list.matrix[3][3] _pdbx_struct_oper_list.vector[3] 1 'identity operation' 1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 2 'crystal symmetry operation' 2_665 -y+1,x-y+1,z -0.5000000000 -0.8660254038 0.0000000000 70.8205000000 0.8660254038 -0.5000000000 0.0000000000 122.6647042174 0.0000000000 0.0000000000 1.0000000000 0.0000000000 3 'crystal symmetry operation' 3_565 -x+y,-x+1,z -0.5000000000 0.8660254038 0.0000000000 -70.8205000000 -0.8660254038 -0.5000000000 0.0000000000 122.6647042174 0.0000000000 0.0000000000 1.0000000000 0.0000000000 # loop_ _pdbx_struct_special_symmetry.id _pdbx_struct_special_symmetry.PDB_model_num _pdbx_struct_special_symmetry.auth_asym_id _pdbx_struct_special_symmetry.auth_comp_id _pdbx_struct_special_symmetry.auth_seq_id _pdbx_struct_special_symmetry.PDB_ins_code _pdbx_struct_special_symmetry.label_asym_id _pdbx_struct_special_symmetry.label_comp_id _pdbx_struct_special_symmetry.label_seq_id 1 1 B HOH 462 ? W HOH . 2 1 B HOH 466 ? W HOH . 3 1 B HOH 515 ? W HOH . 4 1 B HOH 521 ? W HOH . 5 1 B HOH 531 ? W HOH . # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2012-08-22 2 'Structure model' 1 1 2012-10-03 3 'Structure model' 1 2 2018-01-31 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Database references' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 3 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category citation_author # _pdbx_audit_revision_item.ordinal 1 _pdbx_audit_revision_item.revision_ordinal 3 _pdbx_audit_revision_item.data_content_type 'Structure model' _pdbx_audit_revision_item.item '_citation_author.name' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal Blu-Ice 'data collection' . ? 1 PHASER phasing . ? 2 PHENIX refinement '(phenix.refine: 1.7.2_869)' ? 3 HKL-2000 'data reduction' . ? 4 SCALEPACK 'data scaling' . ? 5 # _pdbx_validate_rmsd_bond.id 1 _pdbx_validate_rmsd_bond.PDB_model_num 1 _pdbx_validate_rmsd_bond.auth_atom_id_1 C _pdbx_validate_rmsd_bond.auth_asym_id_1 A _pdbx_validate_rmsd_bond.auth_comp_id_1 HIS _pdbx_validate_rmsd_bond.auth_seq_id_1 117 _pdbx_validate_rmsd_bond.PDB_ins_code_1 ? _pdbx_validate_rmsd_bond.label_alt_id_1 ? _pdbx_validate_rmsd_bond.auth_atom_id_2 N _pdbx_validate_rmsd_bond.auth_asym_id_2 A _pdbx_validate_rmsd_bond.auth_comp_id_2 PHE _pdbx_validate_rmsd_bond.auth_seq_id_2 118 _pdbx_validate_rmsd_bond.PDB_ins_code_2 ? _pdbx_validate_rmsd_bond.label_alt_id_2 ? _pdbx_validate_rmsd_bond.bond_value 1.598 _pdbx_validate_rmsd_bond.bond_target_value 1.336 _pdbx_validate_rmsd_bond.bond_deviation 0.262 _pdbx_validate_rmsd_bond.bond_standard_deviation 0.023 _pdbx_validate_rmsd_bond.linker_flag Y # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 NE B ARG 106 ? ? CZ B ARG 106 ? ? NH1 B ARG 106 ? ? 126.42 120.30 6.12 0.50 N 2 1 NE B ARG 106 ? ? CZ B ARG 106 ? ? NH2 B ARG 106 ? ? 116.56 120.30 -3.74 0.50 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ARG A 62 ? ? 56.04 -117.43 2 1 ASP A 96 ? ? -133.03 -112.27 3 1 CYS A 139 ? ? -119.76 63.67 4 1 SER A 146 ? ? -146.86 -157.37 5 1 GLN A 196 ? ? 70.11 -62.22 6 1 THR A 206 ? ? -135.39 -155.54 7 1 ASN A 240 ? ? 72.72 -0.47 8 1 ALA B 5 ? ? -92.49 -65.48 9 1 ARG B 127 ? ? 48.46 -132.65 10 1 LEU H 189 ? ? -141.59 -42.83 11 1 THR H 191 ? ? -133.28 -66.55 12 1 ALA L 3 ? ? 61.94 -58.39 13 1 ASN L 27 B ? -119.36 -91.62 14 1 ASN L 51 ? ? 79.12 -47.37 15 1 ASP L 151 ? ? 56.02 -101.47 # _pdbx_validate_peptide_omega.id 1 _pdbx_validate_peptide_omega.PDB_model_num 1 _pdbx_validate_peptide_omega.auth_comp_id_1 PHE _pdbx_validate_peptide_omega.auth_asym_id_1 A _pdbx_validate_peptide_omega.auth_seq_id_1 118 _pdbx_validate_peptide_omega.PDB_ins_code_1 ? _pdbx_validate_peptide_omega.label_alt_id_1 ? _pdbx_validate_peptide_omega.auth_comp_id_2 GLU _pdbx_validate_peptide_omega.auth_asym_id_2 A _pdbx_validate_peptide_omega.auth_seq_id_2 119 _pdbx_validate_peptide_omega.PDB_ins_code_2 ? _pdbx_validate_peptide_omega.label_alt_id_2 ? _pdbx_validate_peptide_omega.omega 149.46 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ALA 7 ? A ALA 1 2 1 Y 1 A GLN 325 ? A GLN 326 3 1 Y 1 A ARG 326 ? A ARG 327 4 1 Y 1 A GLU 327 ? A GLU 328 5 1 Y 1 A ARG 328 ? A ARG 329 6 1 Y 1 A ARG 329 ? A ARG 330 7 1 Y 1 A ARG 330 ? A ARG 331 8 1 Y 1 A LYS 331 ? A LYS 332 9 1 Y 1 A LYS 332 ? A LYS 333 10 1 Y 1 A ARG 333 ? A ARG 334 11 1 Y 1 B ARG 177 ? B ARG 177 12 1 Y 1 H SER 127 ? C SER 135 13 1 Y 1 H SER 128 ? C SER 136 14 1 Y 1 H LYS 129 ? C LYS 137 15 1 Y 1 H SER 130 ? C SER 138 16 1 Y 1 H THR 131 ? C THR 139 17 1 Y 1 H SER 132 ? C SER 140 18 1 Y 1 H LYS 214 ? C LYS 222 19 1 Y 1 H SER 215 ? C SER 223 20 1 Y 1 H CYS 216 ? C CYS 224 21 1 Y 1 H HIS 217 ? C HIS 225 22 1 Y 1 H HIS 218 ? C HIS 226 23 1 Y 1 H HIS 219 ? C HIS 227 24 1 Y 1 H HIS 220 ? C HIS 228 25 1 Y 1 H HIS 221 ? C HIS 229 26 1 Y 1 H HIS 222 ? C HIS 230 27 1 Y 1 L GLN 1 ? D GLN 1 28 1 Y 1 L THR 209 ? D THR 213 29 1 Y 1 L GLU 210 ? D GLU 214 30 1 Y 1 L CYS 211 ? D CYS 215 31 1 Y 1 L SER 212 ? D SER 216 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 5 1,2-ETHANEDIOL EDO 6 N-ACETYL-D-GLUCOSAMINE NAG 7 GLYCEROL GOL 8 water HOH #