data_4EY8 # _entry.id 4EY8 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 4EY8 RCSB RCSB072218 WWPDB D_1000072218 # _pdbx_database_status.entry_id 4EY8 _pdbx_database_status.status_code REL _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2012-05-01 _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Cheung, J.' 1 'Rudolph, M.' 2 'Burshteyn, F.' 3 'Cassidy, M.' 4 'Gary, E.' 5 'Love, J.' 6 'Height, J.' 7 'Franklin, M.' 8 # _citation.id primary _citation.title 'Structures of human acetylcholinesterase in complex with pharmacologically important ligands.' _citation.journal_abbrev J.Med.Chem. _citation.journal_volume 55 _citation.page_first 10282 _citation.page_last 10286 _citation.year 2012 _citation.journal_id_ASTM JMCMAR _citation.country US _citation.journal_id_ISSN 0022-2623 _citation.journal_id_CSD 0151 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 23035744 _citation.pdbx_database_id_DOI 10.1021/jm300871x # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Cheung, J.' 1 primary 'Rudolph, M.J.' 2 primary 'Burshteyn, F.' 3 primary 'Cassidy, M.S.' 4 primary 'Gary, E.N.' 5 primary 'Love, J.' 6 primary 'Franklin, M.C.' 7 primary 'Height, J.J.' 8 # _cell.entry_id 4EY8 _cell.length_a 151.705 _cell.length_b 151.705 _cell.length_c 247.862 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 120.00 _cell.Z_PDB 18 _cell.pdbx_unique_axis ? # _symmetry.entry_id 4EY8 _symmetry.space_group_name_H-M 'H 3 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 155 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man Acetylcholinesterase 59447.105 1 3.1.1.7 ? 'UNP Residues 33-574' ? 2 polymer nat Fasciculin-2 6768.769 1 ? ? ? ? 3 non-polymer syn 'SULFATE ION' 96.063 4 ? ? ? ? 4 non-polymer man ALPHA-L-FUCOSE 164.156 1 ? ? ? ? 5 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 3 ? ? ? ? 6 non-polymer man BETA-D-MANNOSE 180.156 1 ? ? ? ? 7 water nat water 18.015 44 ? ? ? ? # loop_ _entity_name_com.entity_id _entity_name_com.name 1 AChE 2 'Fas-2, Fas2, Acetylcholinesterase toxin F-VII, Fasciculin-II, FAS-II, Toxin TA1' # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;GREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFE GTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLAL PGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGM GEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDF HGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDV VGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWA NFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSAT ; ;GREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFE GTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLAL PGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGM GEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDF HGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDV VGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWA NFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSAT ; A ? 2 'polypeptide(L)' no no TMCYSHTTTSRAILTNCGENSCYRKSRRHPPKMVLGRGCGCPPGDDNLEVKCCTSPDKCNY TMCYSHTTTSRAILTNCGENSCYRKSRRHPPKMVLGRGCGCPPGDDNLEVKCCTSPDKCNY B ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLY n 1 2 ARG n 1 3 GLU n 1 4 ASP n 1 5 ALA n 1 6 GLU n 1 7 LEU n 1 8 LEU n 1 9 VAL n 1 10 THR n 1 11 VAL n 1 12 ARG n 1 13 GLY n 1 14 GLY n 1 15 ARG n 1 16 LEU n 1 17 ARG n 1 18 GLY n 1 19 ILE n 1 20 ARG n 1 21 LEU n 1 22 LYS n 1 23 THR n 1 24 PRO n 1 25 GLY n 1 26 GLY n 1 27 PRO n 1 28 VAL n 1 29 SER n 1 30 ALA n 1 31 PHE n 1 32 LEU n 1 33 GLY n 1 34 ILE n 1 35 PRO n 1 36 PHE n 1 37 ALA n 1 38 GLU n 1 39 PRO n 1 40 PRO n 1 41 MET n 1 42 GLY n 1 43 PRO n 1 44 ARG n 1 45 ARG n 1 46 PHE n 1 47 LEU n 1 48 PRO n 1 49 PRO n 1 50 GLU n 1 51 PRO n 1 52 LYS n 1 53 GLN n 1 54 PRO n 1 55 TRP n 1 56 SER n 1 57 GLY n 1 58 VAL n 1 59 VAL n 1 60 ASP n 1 61 ALA n 1 62 THR n 1 63 THR n 1 64 PHE n 1 65 GLN n 1 66 SER n 1 67 VAL n 1 68 CYS n 1 69 TYR n 1 70 GLN n 1 71 TYR n 1 72 VAL n 1 73 ASP n 1 74 THR n 1 75 LEU n 1 76 TYR n 1 77 PRO n 1 78 GLY n 1 79 PHE n 1 80 GLU n 1 81 GLY n 1 82 THR n 1 83 GLU n 1 84 MET n 1 85 TRP n 1 86 ASN n 1 87 PRO n 1 88 ASN n 1 89 ARG n 1 90 GLU n 1 91 LEU n 1 92 SER n 1 93 GLU n 1 94 ASP n 1 95 CYS n 1 96 LEU n 1 97 TYR n 1 98 LEU n 1 99 ASN n 1 100 VAL n 1 101 TRP n 1 102 THR n 1 103 PRO n 1 104 TYR n 1 105 PRO n 1 106 ARG n 1 107 PRO n 1 108 THR n 1 109 SER n 1 110 PRO n 1 111 THR n 1 112 PRO n 1 113 VAL n 1 114 LEU n 1 115 VAL n 1 116 TRP n 1 117 ILE n 1 118 TYR n 1 119 GLY n 1 120 GLY n 1 121 GLY n 1 122 PHE n 1 123 TYR n 1 124 SER n 1 125 GLY n 1 126 ALA n 1 127 SER n 1 128 SER n 1 129 LEU n 1 130 ASP n 1 131 VAL n 1 132 TYR n 1 133 ASP n 1 134 GLY n 1 135 ARG n 1 136 PHE n 1 137 LEU n 1 138 VAL n 1 139 GLN n 1 140 ALA n 1 141 GLU n 1 142 ARG n 1 143 THR n 1 144 VAL n 1 145 LEU n 1 146 VAL n 1 147 SER n 1 148 MET n 1 149 ASN n 1 150 TYR n 1 151 ARG n 1 152 VAL n 1 153 GLY n 1 154 ALA n 1 155 PHE n 1 156 GLY n 1 157 PHE n 1 158 LEU n 1 159 ALA n 1 160 LEU n 1 161 PRO n 1 162 GLY n 1 163 SER n 1 164 ARG n 1 165 GLU n 1 166 ALA n 1 167 PRO n 1 168 GLY n 1 169 ASN n 1 170 VAL n 1 171 GLY n 1 172 LEU n 1 173 LEU n 1 174 ASP n 1 175 GLN n 1 176 ARG n 1 177 LEU n 1 178 ALA n 1 179 LEU n 1 180 GLN n 1 181 TRP n 1 182 VAL n 1 183 GLN n 1 184 GLU n 1 185 ASN n 1 186 VAL n 1 187 ALA n 1 188 ALA n 1 189 PHE n 1 190 GLY n 1 191 GLY n 1 192 ASP n 1 193 PRO n 1 194 THR n 1 195 SER n 1 196 VAL n 1 197 THR n 1 198 LEU n 1 199 PHE n 1 200 GLY n 1 201 GLU n 1 202 SER n 1 203 ALA n 1 204 GLY n 1 205 ALA n 1 206 ALA n 1 207 SER n 1 208 VAL n 1 209 GLY n 1 210 MET n 1 211 HIS n 1 212 LEU n 1 213 LEU n 1 214 SER n 1 215 PRO n 1 216 PRO n 1 217 SER n 1 218 ARG n 1 219 GLY n 1 220 LEU n 1 221 PHE n 1 222 HIS n 1 223 ARG n 1 224 ALA n 1 225 VAL n 1 226 LEU n 1 227 GLN n 1 228 SER n 1 229 GLY n 1 230 ALA n 1 231 PRO n 1 232 ASN n 1 233 GLY n 1 234 PRO n 1 235 TRP n 1 236 ALA n 1 237 THR n 1 238 VAL n 1 239 GLY n 1 240 MET n 1 241 GLY n 1 242 GLU n 1 243 ALA n 1 244 ARG n 1 245 ARG n 1 246 ARG n 1 247 ALA n 1 248 THR n 1 249 GLN n 1 250 LEU n 1 251 ALA n 1 252 HIS n 1 253 LEU n 1 254 VAL n 1 255 GLY n 1 256 CYS n 1 257 PRO n 1 258 PRO n 1 259 GLY n 1 260 GLY n 1 261 THR n 1 262 GLY n 1 263 GLY n 1 264 ASN n 1 265 ASP n 1 266 THR n 1 267 GLU n 1 268 LEU n 1 269 VAL n 1 270 ALA n 1 271 CYS n 1 272 LEU n 1 273 ARG n 1 274 THR n 1 275 ARG n 1 276 PRO n 1 277 ALA n 1 278 GLN n 1 279 VAL n 1 280 LEU n 1 281 VAL n 1 282 ASN n 1 283 HIS n 1 284 GLU n 1 285 TRP n 1 286 HIS n 1 287 VAL n 1 288 LEU n 1 289 PRO n 1 290 GLN n 1 291 GLU n 1 292 SER n 1 293 VAL n 1 294 PHE n 1 295 ARG n 1 296 PHE n 1 297 SER n 1 298 PHE n 1 299 VAL n 1 300 PRO n 1 301 VAL n 1 302 VAL n 1 303 ASP n 1 304 GLY n 1 305 ASP n 1 306 PHE n 1 307 LEU n 1 308 SER n 1 309 ASP n 1 310 THR n 1 311 PRO n 1 312 GLU n 1 313 ALA n 1 314 LEU n 1 315 ILE n 1 316 ASN n 1 317 ALA n 1 318 GLY n 1 319 ASP n 1 320 PHE n 1 321 HIS n 1 322 GLY n 1 323 LEU n 1 324 GLN n 1 325 VAL n 1 326 LEU n 1 327 VAL n 1 328 GLY n 1 329 VAL n 1 330 VAL n 1 331 LYS n 1 332 ASP n 1 333 GLU n 1 334 GLY n 1 335 SER n 1 336 TYR n 1 337 PHE n 1 338 LEU n 1 339 VAL n 1 340 TYR n 1 341 GLY n 1 342 ALA n 1 343 PRO n 1 344 GLY n 1 345 PHE n 1 346 SER n 1 347 LYS n 1 348 ASP n 1 349 ASN n 1 350 GLU n 1 351 SER n 1 352 LEU n 1 353 ILE n 1 354 SER n 1 355 ARG n 1 356 ALA n 1 357 GLU n 1 358 PHE n 1 359 LEU n 1 360 ALA n 1 361 GLY n 1 362 VAL n 1 363 ARG n 1 364 VAL n 1 365 GLY n 1 366 VAL n 1 367 PRO n 1 368 GLN n 1 369 VAL n 1 370 SER n 1 371 ASP n 1 372 LEU n 1 373 ALA n 1 374 ALA n 1 375 GLU n 1 376 ALA n 1 377 VAL n 1 378 VAL n 1 379 LEU n 1 380 HIS n 1 381 TYR n 1 382 THR n 1 383 ASP n 1 384 TRP n 1 385 LEU n 1 386 HIS n 1 387 PRO n 1 388 GLU n 1 389 ASP n 1 390 PRO n 1 391 ALA n 1 392 ARG n 1 393 LEU n 1 394 ARG n 1 395 GLU n 1 396 ALA n 1 397 LEU n 1 398 SER n 1 399 ASP n 1 400 VAL n 1 401 VAL n 1 402 GLY n 1 403 ASP n 1 404 HIS n 1 405 ASN n 1 406 VAL n 1 407 VAL n 1 408 CYS n 1 409 PRO n 1 410 VAL n 1 411 ALA n 1 412 GLN n 1 413 LEU n 1 414 ALA n 1 415 GLY n 1 416 ARG n 1 417 LEU n 1 418 ALA n 1 419 ALA n 1 420 GLN n 1 421 GLY n 1 422 ALA n 1 423 ARG n 1 424 VAL n 1 425 TYR n 1 426 ALA n 1 427 TYR n 1 428 VAL n 1 429 PHE n 1 430 GLU n 1 431 HIS n 1 432 ARG n 1 433 ALA n 1 434 SER n 1 435 THR n 1 436 LEU n 1 437 SER n 1 438 TRP n 1 439 PRO n 1 440 LEU n 1 441 TRP n 1 442 MET n 1 443 GLY n 1 444 VAL n 1 445 PRO n 1 446 HIS n 1 447 GLY n 1 448 TYR n 1 449 GLU n 1 450 ILE n 1 451 GLU n 1 452 PHE n 1 453 ILE n 1 454 PHE n 1 455 GLY n 1 456 ILE n 1 457 PRO n 1 458 LEU n 1 459 ASP n 1 460 PRO n 1 461 SER n 1 462 ARG n 1 463 ASN n 1 464 TYR n 1 465 THR n 1 466 ALA n 1 467 GLU n 1 468 GLU n 1 469 LYS n 1 470 ILE n 1 471 PHE n 1 472 ALA n 1 473 GLN n 1 474 ARG n 1 475 LEU n 1 476 MET n 1 477 ARG n 1 478 TYR n 1 479 TRP n 1 480 ALA n 1 481 ASN n 1 482 PHE n 1 483 ALA n 1 484 ARG n 1 485 THR n 1 486 GLY n 1 487 ASP n 1 488 PRO n 1 489 ASN n 1 490 GLU n 1 491 PRO n 1 492 ARG n 1 493 ASP n 1 494 PRO n 1 495 LYS n 1 496 ALA n 1 497 PRO n 1 498 GLN n 1 499 TRP n 1 500 PRO n 1 501 PRO n 1 502 TYR n 1 503 THR n 1 504 ALA n 1 505 GLY n 1 506 ALA n 1 507 GLN n 1 508 GLN n 1 509 TYR n 1 510 VAL n 1 511 SER n 1 512 LEU n 1 513 ASP n 1 514 LEU n 1 515 ARG n 1 516 PRO n 1 517 LEU n 1 518 GLU n 1 519 VAL n 1 520 ARG n 1 521 ARG n 1 522 GLY n 1 523 LEU n 1 524 ARG n 1 525 ALA n 1 526 GLN n 1 527 ALA n 1 528 CYS n 1 529 ALA n 1 530 PHE n 1 531 TRP n 1 532 ASN n 1 533 ARG n 1 534 PHE n 1 535 LEU n 1 536 PRO n 1 537 LYS n 1 538 LEU n 1 539 LEU n 1 540 SER n 1 541 ALA n 1 542 THR n 2 1 THR n 2 2 MET n 2 3 CYS n 2 4 TYR n 2 5 SER n 2 6 HIS n 2 7 THR n 2 8 THR n 2 9 THR n 2 10 SER n 2 11 ARG n 2 12 ALA n 2 13 ILE n 2 14 LEU n 2 15 THR n 2 16 ASN n 2 17 CYS n 2 18 GLY n 2 19 GLU n 2 20 ASN n 2 21 SER n 2 22 CYS n 2 23 TYR n 2 24 ARG n 2 25 LYS n 2 26 SER n 2 27 ARG n 2 28 ARG n 2 29 HIS n 2 30 PRO n 2 31 PRO n 2 32 LYS n 2 33 MET n 2 34 VAL n 2 35 LEU n 2 36 GLY n 2 37 ARG n 2 38 GLY n 2 39 CYS n 2 40 GLY n 2 41 CYS n 2 42 PRO n 2 43 PRO n 2 44 GLY n 2 45 ASP n 2 46 ASP n 2 47 ASN n 2 48 LEU n 2 49 GLU n 2 50 VAL n 2 51 LYS n 2 52 CYS n 2 53 CYS n 2 54 THR n 2 55 SER n 2 56 PRO n 2 57 ASP n 2 58 LYS n 2 59 CYS n 2 60 ASN n 2 61 TYR n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene ACHE _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 9606 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue HEK-293 _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _entity_src_nat.entity_id 2 _entity_src_nat.pdbx_src_id 1 _entity_src_nat.pdbx_alt_source_flag sample _entity_src_nat.pdbx_beg_seq_num ? _entity_src_nat.pdbx_end_seq_num ? _entity_src_nat.common_name 'eastern green mamba' _entity_src_nat.pdbx_organism_scientific 'Dendroaspis angusticeps' _entity_src_nat.pdbx_ncbi_taxonomy_id 8618 _entity_src_nat.genus Dendroaspis _entity_src_nat.species ? _entity_src_nat.strain ? _entity_src_nat.tissue ? _entity_src_nat.tissue_fraction ? _entity_src_nat.pdbx_secretion VENOM _entity_src_nat.pdbx_fragment ? _entity_src_nat.pdbx_variant ? _entity_src_nat.pdbx_cell_line ? _entity_src_nat.pdbx_atcc ? _entity_src_nat.pdbx_cellular_location ? _entity_src_nat.pdbx_organ ? _entity_src_nat.pdbx_organelle ? _entity_src_nat.pdbx_cell ? _entity_src_nat.pdbx_plasmid_name ? _entity_src_nat.pdbx_plasmid_details ? _entity_src_nat.details ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin _struct_ref.pdbx_db_isoform 1 UNP ACES_HUMAN P22303 1 ;GREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFE GTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLAL PGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGM GEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDF HGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDV VGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWA NFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSAT ; 33 ? 2 UNP TXFA2_DENAN P0C1Z0 2 TMCYSHTTTSRAILTNCGENSCYRKSRRHPPKMVLGRGCGCPPGDDNLEVKCCTSPDKCNY 1 ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 4EY8 A 1 ? 542 ? P22303 33 ? 574 ? 2 543 2 2 4EY8 B 1 ? 61 ? P0C1Z0 1 ? 61 ? 1 61 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FUC saccharide . ALPHA-L-FUCOSE ? 'C6 H12 O5' 164.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 4EY8 _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 4.14 _exptl_crystal.density_percent_sol 70.32 _exptl_crystal.description ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.temp 283 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pdbx_pH_range '7.5 - 7.8' _exptl_crystal_grow.pdbx_details '1.6 to 2.0M ammonium sulphate, 0.1M HEPES pH 7.5 - 7.8, VAPOR DIFFUSION, SITTING DROP, temperature 283K' # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'MAR CCD 165 mm' _diffrn_detector.pdbx_collection_date 2012-01-01 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'Si(111)' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.990 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'NSLS BEAMLINE X4C' _diffrn_source.pdbx_synchrotron_site NSLS _diffrn_source.pdbx_synchrotron_beamline X4C _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.990 # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 4EY8 _reflns.observed_criterion_sigma_I -3 _reflns.observed_criterion_sigma_F 0 _reflns.d_resolution_low 50.000 _reflns.d_resolution_high 2.5958 _reflns.number_obs 33704 _reflns.number_all 34182 _reflns.percent_possible_obs 98.600 _reflns.pdbx_Rmerge_I_obs 0.054 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 11.100 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 5.000 # loop_ _reflns_shell.pdbx_diffrn_id _reflns_shell.pdbx_ordinal _reflns_shell.d_res_high _reflns_shell.d_res_low _reflns_shell.percent_possible_all _reflns_shell.Rmerge_I_obs _reflns_shell.pdbx_Rsym_value _reflns_shell.meanI_over_sigI_obs _reflns_shell.pdbx_redundancy 1 1 2.5958 2.640 88.500 0.290 ? ? 3.600 1 2 2.640 2.690 94.700 0.308 ? ? 3.900 1 3 2.690 2.740 98.900 0.320 ? ? 4.200 1 4 2.740 2.800 100.000 0.300 ? ? 4.500 1 5 2.800 2.860 99.900 0.254 ? ? 4.600 1 6 2.860 2.930 100.000 0.218 ? ? 4.700 1 7 2.930 3.000 99.900 0.179 ? ? 4.700 1 8 3.000 3.080 99.900 0.158 ? ? 4.700 1 9 3.080 3.170 99.900 0.134 ? ? 4.700 1 10 3.170 3.280 99.600 0.106 ? ? 4.700 1 11 3.280 3.390 99.900 0.095 ? ? 4.700 1 12 3.390 3.530 99.500 0.086 ? ? 4.700 1 13 3.530 3.690 99.500 0.071 ? ? 4.700 1 14 3.690 3.880 99.200 0.062 ? ? 4.700 1 15 3.880 4.130 99.300 0.056 ? ? 4.600 1 16 4.130 4.450 99.200 0.049 ? ? 4.600 1 17 4.450 4.890 99.000 0.045 ? ? 4.600 1 18 4.890 5.600 99.200 0.044 ? ? 5.100 1 19 5.600 7.050 99.100 0.048 ? ? 9.300 1 20 7.050 50.000 97.600 0.032 ? ? 8.200 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 4EY8 _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 33413 _refine.ls_number_reflns_all 35893 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.00 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 46.381 _refine.ls_d_res_high 2.5958 _refine.ls_percent_reflns_obs 97.78 _refine.ls_R_factor_obs 0.1964 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.1939 _refine.ls_R_factor_R_free 0.2439 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.03 _refine.ls_number_reflns_R_free 1681 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min 0.500 _refine.occupancy_max 1.000 _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean ? _refine.aniso_B[1][1] 15.7066 _refine.aniso_B[2][2] 15.7066 _refine.aniso_B[3][3] -31.4132 _refine.aniso_B[1][2] 0.0000 _refine.aniso_B[1][3] -0.0000 _refine.aniso_B[2][3] -0.0000 _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.30 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 1.10 _refine.pdbx_ls_cross_valid_method ? _refine.details ? _refine.pdbx_starting_model 1b41 _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.35 _refine.pdbx_overall_phase_error 30.82 _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 4592 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 83 _refine_hist.number_atoms_solvent 44 _refine_hist.number_atoms_total 4719 _refine_hist.d_res_high 2.5958 _refine_hist.d_res_low 46.381 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function f_bond_d 0.008 ? ? 4829 'X-RAY DIFFRACTION' ? f_angle_d 1.187 ? ? 6590 'X-RAY DIFFRACTION' ? f_dihedral_angle_d 17.080 ? ? 1765 'X-RAY DIFFRACTION' ? f_chiral_restr 0.079 ? ? 713 'X-RAY DIFFRACTION' ? f_plane_restr 0.006 ? ? 859 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_all _refine_ls_shell.R_factor_all 'X-RAY DIFFRACTION' . 2.5958 2.6722 2431 0.2887 90.00 0.3804 . . 125 . . 'X-RAY DIFFRACTION' . 2.6722 2.7584 2616 0.2617 98.00 0.3539 . . 142 . . 'X-RAY DIFFRACTION' . 2.7584 2.8570 2654 0.2581 99.00 0.3179 . . 143 . . 'X-RAY DIFFRACTION' . 2.8570 2.9714 2653 0.2508 99.00 0.3374 . . 141 . . 'X-RAY DIFFRACTION' . 2.9714 3.1066 2659 0.2349 99.00 0.3074 . . 134 . . 'X-RAY DIFFRACTION' . 3.1066 3.2703 2667 0.2484 99.00 0.3220 . . 129 . . 'X-RAY DIFFRACTION' . 3.2703 3.4752 2652 0.2417 99.00 0.3020 . . 131 . . 'X-RAY DIFFRACTION' . 3.4752 3.7434 2618 0.2144 98.00 0.2980 . . 161 . . 'X-RAY DIFFRACTION' . 3.7434 4.1199 2646 0.1779 97.00 0.2310 . . 130 . . 'X-RAY DIFFRACTION' . 4.1199 4.7155 2638 0.1574 98.00 0.2096 . . 162 . . 'X-RAY DIFFRACTION' . 4.7155 5.9391 2703 0.1631 99.00 0.1857 . . 147 . . 'X-RAY DIFFRACTION' . 5.9391 46.3880 2795 0.1613 98.00 0.1875 . . 136 . . # _struct.entry_id 4EY8 _struct.title 'Crystal structure of recombinant human acetylcholinesterase in complex with fasciculin-2' _struct.pdbx_descriptor 'Acetylcholinesterase (E.C.3.1.1.7), Fasciculin-2' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 4EY8 _struct_keywords.text 'acetylcholinesterase, hydrolase, fasciculin 2, snake venom toxin, inhibitor, HYDROLASE-HYDROLASE INHIBITOR complex' _struct_keywords.pdbx_keywords 'HYDROLASE/HYDROLASE INHIBITOR' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 3 ? E N N 3 ? F N N 3 ? G N N 4 ? H N N 5 ? I N N 5 ? J N N 6 ? K N N 5 ? L N N 7 ? M N N 7 ? # _struct_biol.id 1 _struct_biol.details dimer # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 MET A 41 ? ARG A 45 ? MET A 42 ARG A 46 5 ? 5 HELX_P HELX_P2 2 PHE A 79 ? MET A 84 ? PHE A 80 MET A 85 1 ? 6 HELX_P HELX_P3 3 LEU A 129 ? ASP A 133 ? LEU A 130 ASP A 134 5 ? 5 HELX_P HELX_P4 4 GLY A 134 ? ARG A 142 ? GLY A 135 ARG A 143 1 ? 9 HELX_P HELX_P5 5 VAL A 152 ? LEU A 158 ? VAL A 153 LEU A 159 1 ? 7 HELX_P HELX_P6 6 ASN A 169 ? VAL A 186 ? ASN A 170 VAL A 187 1 ? 18 HELX_P HELX_P7 7 ALA A 187 ? PHE A 189 ? ALA A 188 PHE A 190 5 ? 3 HELX_P HELX_P8 8 SER A 202 ? LEU A 212 ? SER A 203 LEU A 213 1 ? 11 HELX_P HELX_P9 9 SER A 214 ? PHE A 221 ? SER A 215 PHE A 222 5 ? 8 HELX_P HELX_P10 10 GLY A 239 ? VAL A 254 ? GLY A 240 VAL A 255 1 ? 16 HELX_P HELX_P11 11 ASP A 265 ? ARG A 275 ? ASP A 266 ARG A 276 1 ? 11 HELX_P HELX_P12 12 PRO A 276 ? TRP A 285 ? PRO A 277 TRP A 286 1 ? 10 HELX_P HELX_P13 13 HIS A 286 ? LEU A 288 ? HIS A 287 LEU A 289 5 ? 3 HELX_P HELX_P14 14 THR A 310 ? GLY A 318 ? THR A 311 GLY A 319 1 ? 9 HELX_P HELX_P15 15 GLY A 334 ? GLY A 341 ? GLY A 335 GLY A 342 5 ? 8 HELX_P HELX_P16 16 SER A 354 ? VAL A 366 ? SER A 355 VAL A 367 1 ? 13 HELX_P HELX_P17 17 SER A 370 ? THR A 382 ? SER A 371 THR A 383 1 ? 13 HELX_P HELX_P18 18 ASP A 389 ? VAL A 406 ? ASP A 390 VAL A 407 1 ? 18 HELX_P HELX_P19 19 VAL A 406 ? ALA A 419 ? VAL A 407 ALA A 420 1 ? 14 HELX_P HELX_P20 20 PRO A 439 ? GLY A 443 ? PRO A 440 GLY A 444 5 ? 5 HELX_P HELX_P21 21 GLU A 449 ? PHE A 454 ? GLU A 450 PHE A 455 1 ? 6 HELX_P HELX_P22 22 GLY A 455 ? ASP A 459 ? GLY A 456 ASP A 460 5 ? 5 HELX_P HELX_P23 23 THR A 465 ? GLY A 486 ? THR A 466 GLY A 487 1 ? 22 HELX_P HELX_P24 24 ARG A 524 ? ARG A 533 ? ARG A 525 ARG A 534 1 ? 10 HELX_P HELX_P25 25 ARG A 533 ? SER A 540 ? ARG A 534 SER A 541 1 ? 8 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 68 SG ? ? ? 1_555 A CYS 95 SG ? ? A CYS 69 A CYS 96 1_555 ? ? ? ? ? ? ? 2.064 ? disulf2 disulf ? ? A CYS 256 SG ? ? ? 1_555 A CYS 271 SG ? ? A CYS 257 A CYS 272 1_555 ? ? ? ? ? ? ? 2.060 ? disulf3 disulf ? ? A CYS 408 SG ? ? ? 1_555 A CYS 528 SG ? ? A CYS 409 A CYS 529 1_555 ? ? ? ? ? ? ? 2.074 ? disulf4 disulf ? ? B CYS 3 SG ? ? ? 1_555 B CYS 22 SG ? ? B CYS 3 B CYS 22 1_555 ? ? ? ? ? ? ? 2.029 ? disulf5 disulf ? ? B CYS 17 SG ? ? ? 1_555 B CYS 39 SG ? ? B CYS 17 B CYS 39 1_555 ? ? ? ? ? ? ? 2.044 ? disulf6 disulf ? ? B CYS 41 SG ? ? ? 1_555 B CYS 52 SG ? ? B CYS 41 B CYS 52 1_555 ? ? ? ? ? ? ? 2.050 ? disulf7 disulf ? ? B CYS 53 SG ? ? ? 1_555 B CYS 59 SG ? ? B CYS 53 B CYS 59 1_555 ? ? ? ? ? ? ? 2.042 ? covale1 covale ? ? G FUC . C1 ? ? ? 1_555 H NAG . O6 ? ? A FUC 605 A NAG 606 1_555 ? ? ? ? ? ? ? 1.213 ? covale2 covale ? ? A ASN 463 ND2 ? ? ? 1_555 K NAG . C1 ? ? A ASN 464 A NAG 609 1_555 ? ? ? ? ? ? ? 1.480 ? covale3 covale ? ? A ASN 349 ND2 ? ? ? 1_555 H NAG . C1 ? ? A ASN 350 A NAG 606 1_555 ? ? ? ? ? ? ? 1.530 ? covale4 covale ? ? I NAG . O4 ? ? ? 1_555 J BMA . C1 ? ? A NAG 607 A BMA 608 1_555 ? ? ? ? ? ? ? 1.547 ? covale5 covale ? ? H NAG . O4 ? ? ? 1_555 I NAG . C1 ? ? A NAG 606 A NAG 607 1_555 ? ? ? ? ? ? ? 1.554 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 TYR 104 A . ? TYR 105 A PRO 105 A ? PRO 106 A 1 3.10 2 PRO 491 A . ? PRO 492 A ARG 492 A ? ARG 493 A 1 2.85 3 PRO 30 B . ? PRO 30 B PRO 31 B ? PRO 31 B 1 4.70 4 SER 55 B . ? SER 55 B PRO 56 B ? PRO 56 B 1 -5.37 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 3 ? B ? 11 ? C ? 2 ? D ? 2 ? E ? 2 ? F ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel B 4 5 ? parallel B 5 6 ? parallel B 6 7 ? parallel B 7 8 ? parallel B 8 9 ? parallel B 9 10 ? parallel B 10 11 ? anti-parallel C 1 2 ? anti-parallel D 1 2 ? parallel E 1 2 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 LEU A 8 ? VAL A 11 ? LEU A 9 VAL A 12 A 2 GLY A 14 ? ARG A 17 ? GLY A 15 ARG A 18 A 3 VAL A 58 ? ASP A 60 ? VAL A 59 ASP A 61 B 1 ILE A 19 ? LEU A 21 ? ILE A 20 LEU A 22 B 2 VAL A 28 ? PRO A 35 ? VAL A 29 PRO A 36 B 3 TYR A 97 ? PRO A 103 ? TYR A 98 PRO A 104 B 4 VAL A 144 ? MET A 148 ? VAL A 145 MET A 149 B 5 THR A 111 ? ILE A 117 ? THR A 112 ILE A 118 B 6 GLY A 191 ? GLU A 201 ? GLY A 192 GLU A 202 B 7 ARG A 223 ? GLN A 227 ? ARG A 224 GLN A 228 B 8 GLN A 324 ? VAL A 330 ? GLN A 325 VAL A 331 B 9 ARG A 423 ? PHE A 429 ? ARG A 424 PHE A 430 B 10 GLN A 508 ? LEU A 512 ? GLN A 509 LEU A 513 B 11 GLU A 518 ? ARG A 521 ? GLU A 519 ARG A 522 C 1 ALA A 37 ? GLU A 38 ? ALA A 38 GLU A 39 C 2 GLU A 50 ? PRO A 51 ? GLU A 51 PRO A 52 D 1 VAL A 67 ? CYS A 68 ? VAL A 68 CYS A 69 D 2 LEU A 91 ? SER A 92 ? LEU A 92 SER A 93 E 1 MET B 2 ? SER B 5 ? MET B 2 SER B 5 E 2 ILE B 13 ? ASN B 16 ? ILE B 13 ASN B 16 F 1 VAL B 34 ? CYS B 39 ? VAL B 34 CYS B 39 F 2 CYS B 22 ? ARG B 27 ? CYS B 22 ARG B 27 F 3 LEU B 48 ? CYS B 53 ? LEU B 48 CYS B 53 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 9 ? N VAL A 10 O LEU A 16 ? O LEU A 17 A 2 3 N ARG A 15 ? N ARG A 16 O VAL A 59 ? O VAL A 60 B 1 2 N LEU A 21 ? N LEU A 22 O VAL A 28 ? O VAL A 29 B 2 3 N PHE A 31 ? N PHE A 32 O VAL A 100 ? O VAL A 101 B 3 4 N TRP A 101 ? N TRP A 102 O LEU A 145 ? O LEU A 146 B 4 5 O VAL A 146 ? O VAL A 147 N TRP A 116 ? N TRP A 117 B 5 6 N VAL A 115 ? N VAL A 116 O PHE A 199 ? O PHE A 200 B 6 7 N LEU A 198 ? N LEU A 199 O VAL A 225 ? O VAL A 226 B 7 8 N ALA A 224 ? N ALA A 225 O LEU A 326 ? O LEU A 327 B 8 9 N VAL A 327 ? N VAL A 328 O TYR A 425 ? O TYR A 426 B 9 10 N VAL A 428 ? N VAL A 429 O VAL A 510 ? O VAL A 511 B 10 11 N TYR A 509 ? N TYR A 510 O ARG A 520 ? O ARG A 521 C 1 2 N GLU A 38 ? N GLU A 39 O GLU A 50 ? O GLU A 51 D 1 2 N VAL A 67 ? N VAL A 68 O SER A 92 ? O SER A 93 E 1 2 N SER B 5 ? N SER B 5 O ILE B 13 ? O ILE B 13 F 1 2 O GLY B 36 ? O GLY B 36 N LYS B 25 ? N LYS B 25 F 2 3 N SER B 26 ? N SER B 26 O GLU B 49 ? O GLU B 49 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE SO4 A 601' AC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE SO4 A 602' AC3 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE SO4 A 603' AC4 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE SO4 A 604' AC5 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE FUC A 605' AC6 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG A 606' AC7 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 607' AC8 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE BMA A 608' AC9 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 609' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 ARG A 524 ? ARG A 525 . ? 1_555 ? 2 AC1 4 ALA A 525 ? ALA A 526 . ? 1_555 ? 3 AC1 4 GLN A 526 ? GLN A 527 . ? 1_555 ? 4 AC1 4 ALA A 527 ? ALA A 528 . ? 1_555 ? 5 AC2 3 GLY A 239 ? GLY A 240 . ? 1_555 ? 6 AC2 3 MET A 240 ? MET A 241 . ? 1_555 ? 7 AC2 3 GLY A 241 ? GLY A 242 . ? 1_555 ? 8 AC3 3 THR A 503 ? THR A 504 . ? 1_555 ? 9 AC3 3 GLY A 505 ? GLY A 506 . ? 1_555 ? 10 AC3 3 ALA A 506 ? ALA A 507 . ? 1_555 ? 11 AC4 4 ARG A 15 ? ARG A 16 . ? 1_555 ? 12 AC4 4 SER A 56 ? SER A 57 . ? 1_555 ? 13 AC4 4 GLY A 57 ? GLY A 58 . ? 1_555 ? 14 AC4 4 ARG A 164 ? ARG A 165 . ? 18_445 ? 15 AC5 2 SER A 346 ? SER A 347 . ? 1_555 ? 16 AC5 2 NAG H . ? NAG A 606 . ? 1_555 ? 17 AC6 4 SER A 346 ? SER A 347 . ? 1_555 ? 18 AC6 4 ASN A 349 ? ASN A 350 . ? 1_555 ? 19 AC6 4 FUC G . ? FUC A 605 . ? 1_555 ? 20 AC6 4 NAG I . ? NAG A 607 . ? 1_555 ? 21 AC7 3 GLY A 344 ? GLY A 345 . ? 1_555 ? 22 AC7 3 NAG H . ? NAG A 606 . ? 1_555 ? 23 AC7 3 BMA J . ? BMA A 608 . ? 1_555 ? 24 AC8 1 NAG I . ? NAG A 607 . ? 1_555 ? 25 AC9 2 SER A 461 ? SER A 462 . ? 1_555 ? 26 AC9 2 ASN A 463 ? ASN A 464 . ? 1_555 ? # _atom_sites.entry_id 4EY8 _atom_sites.fract_transf_matrix[1][1] 0.006592 _atom_sites.fract_transf_matrix[1][2] 0.003806 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.007611 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.004035 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ASP A 1 4 ? -5.652 -15.076 81.302 1.00 89.00 ? 5 ASP A N 1 ATOM 2 C CA . ASP A 1 4 ? -6.523 -14.365 82.232 1.00 93.92 ? 5 ASP A CA 1 ATOM 3 C C . ASP A 1 4 ? -7.354 -15.323 83.066 1.00 94.34 ? 5 ASP A C 1 ATOM 4 O O . ASP A 1 4 ? -7.649 -16.434 82.632 1.00 85.82 ? 5 ASP A O 1 ATOM 5 C CB . ASP A 1 4 ? -7.461 -13.425 81.476 1.00 94.76 ? 5 ASP A CB 1 ATOM 6 C CG . ASP A 1 4 ? -6.722 -12.310 80.783 1.00 116.38 ? 5 ASP A CG 1 ATOM 7 O OD1 . ASP A 1 4 ? -5.759 -11.788 81.384 1.00 129.54 ? 5 ASP A OD1 1 ATOM 8 O OD2 . ASP A 1 4 ? -7.097 -11.958 79.640 1.00 115.72 ? 5 ASP A OD2 1 ATOM 9 N N . ALA A 1 5 ? -7.738 -14.876 84.263 1.00 103.48 ? 6 ALA A N 1 ATOM 10 C CA . ALA A 1 5 ? -8.673 -15.611 85.117 1.00 92.27 ? 6 ALA A CA 1 ATOM 11 C C . ALA A 1 5 ? -10.096 -15.326 84.654 1.00 91.81 ? 6 ALA A C 1 ATOM 12 O O . ALA A 1 5 ? -11.072 -15.748 85.287 1.00 87.19 ? 6 ALA A O 1 ATOM 13 C CB . ALA A 1 5 ? -8.505 -15.207 86.575 1.00 83.93 ? 6 ALA A CB 1 ATOM 14 N N . GLU A 1 6 ? -10.198 -14.592 83.548 1.00 87.23 ? 7 GLU A N 1 ATOM 15 C CA . GLU A 1 6 ? -11.482 -14.268 82.951 1.00 87.38 ? 7 GLU A CA 1 ATOM 16 C C . GLU A 1 6 ? -11.843 -15.268 81.875 1.00 80.84 ? 7 GLU A C 1 ATOM 17 O O . GLU A 1 6 ? -13.005 -15.381 81.478 1.00 76.61 ? 7 GLU A O 1 ATOM 18 C CB . GLU A 1 6 ? -11.479 -12.852 82.400 1.00 77.59 ? 7 GLU A CB 1 ATOM 19 C CG . GLU A 1 6 ? -12.039 -11.888 83.408 1.00 78.15 ? 7 GLU A CG 1 ATOM 20 C CD . GLU A 1 6 ? -12.370 -10.562 82.809 1.00 85.93 ? 7 GLU A CD 1 ATOM 21 O OE1 . GLU A 1 6 ? -11.876 -10.276 81.695 1.00 95.59 ? 7 GLU A OE1 1 ATOM 22 O OE2 . GLU A 1 6 ? -13.129 -9.810 83.451 1.00 89.89 ? 7 GLU A OE2 1 ATOM 23 N N . LEU A 1 7 ? -10.832 -15.999 81.423 1.00 76.35 ? 8 LEU A N 1 ATOM 24 C CA . LEU A 1 7 ? -11.040 -17.090 80.495 1.00 72.49 ? 8 LEU A CA 1 ATOM 25 C C . LEU A 1 7 ? -11.303 -18.392 81.253 1.00 71.84 ? 8 LEU A C 1 ATOM 26 O O . LEU A 1 7 ? -11.344 -19.463 80.653 1.00 74.19 ? 8 LEU A O 1 ATOM 27 C CB . LEU A 1 7 ? -9.844 -17.235 79.545 1.00 74.04 ? 8 LEU A CB 1 ATOM 28 C CG . LEU A 1 7 ? -9.504 -16.037 78.640 1.00 76.46 ? 8 LEU A CG 1 ATOM 29 C CD1 . LEU A 1 7 ? -8.410 -16.417 77.656 1.00 66.82 ? 8 LEU A CD1 1 ATOM 30 C CD2 . LEU A 1 7 ? -10.729 -15.485 77.900 1.00 70.75 ? 8 LEU A CD2 1 ATOM 31 N N . LEU A 1 8 ? -11.482 -18.296 82.570 1.00 72.12 ? 9 LEU A N 1 ATOM 32 C CA . LEU A 1 8 ? -11.876 -19.450 83.383 1.00 69.61 ? 9 LEU A CA 1 ATOM 33 C C . LEU A 1 8 ? -13.227 -19.201 84.034 1.00 70.85 ? 9 LEU A C 1 ATOM 34 O O . LEU A 1 8 ? -13.422 -18.192 84.709 1.00 75.57 ? 9 LEU A O 1 ATOM 35 C CB . LEU A 1 8 ? -10.855 -19.744 84.472 1.00 69.06 ? 9 LEU A CB 1 ATOM 36 C CG . LEU A 1 8 ? -9.413 -20.010 84.058 1.00 74.24 ? 9 LEU A CG 1 ATOM 37 C CD1 . LEU A 1 8 ? -8.619 -20.540 85.266 1.00 57.08 ? 9 LEU A CD1 1 ATOM 38 C CD2 . LEU A 1 8 ? -9.355 -20.979 82.877 1.00 64.17 ? 9 LEU A CD2 1 ATOM 39 N N . VAL A 1 9 ? -14.158 -20.124 83.820 1.00 68.18 ? 10 VAL A N 1 ATOM 40 C CA . VAL A 1 9 ? -15.521 -19.979 84.305 1.00 61.23 ? 10 VAL A CA 1 ATOM 41 C C . VAL A 1 9 ? -16.019 -21.359 84.699 1.00 61.81 ? 10 VAL A C 1 ATOM 42 O O . VAL A 1 9 ? -15.618 -22.371 84.112 1.00 62.21 ? 10 VAL A O 1 ATOM 43 C CB . VAL A 1 9 ? -16.451 -19.311 83.238 1.00 67.83 ? 10 VAL A CB 1 ATOM 44 C CG1 . VAL A 1 9 ? -17.919 -19.443 83.605 1.00 66.15 ? 10 VAL A CG1 1 ATOM 45 C CG2 . VAL A 1 9 ? -16.111 -17.841 83.079 1.00 71.03 ? 10 VAL A CG2 1 ATOM 46 N N . THR A 1 10 ? -16.865 -21.393 85.721 1.00 58.81 ? 11 THR A N 1 ATOM 47 C CA . THR A 1 10 ? -17.458 -22.633 86.185 1.00 68.11 ? 11 THR A CA 1 ATOM 48 C C . THR A 1 10 ? -18.974 -22.602 86.024 1.00 66.66 ? 11 THR A C 1 ATOM 49 O O . THR A 1 10 ? -19.642 -21.689 86.498 1.00 66.02 ? 11 THR A O 1 ATOM 50 C CB . THR A 1 10 ? -17.120 -22.909 87.670 1.00 59.98 ? 11 THR A CB 1 ATOM 51 O OG1 . THR A 1 10 ? -15.697 -22.904 87.847 1.00 63.40 ? 11 THR A OG1 1 ATOM 52 C CG2 . THR A 1 10 ? -17.668 -24.259 88.079 1.00 49.84 ? 11 THR A CG2 1 ATOM 53 N N . VAL A 1 11 ? -19.503 -23.613 85.351 1.00 61.70 ? 12 VAL A N 1 ATOM 54 C CA . VAL A 1 11 ? -20.932 -23.740 85.153 1.00 58.04 ? 12 VAL A CA 1 ATOM 55 C C . VAL A 1 11 ? -21.377 -24.972 85.937 1.00 57.78 ? 12 VAL A C 1 ATOM 56 O O . VAL A 1 11 ? -20.539 -25.688 86.470 1.00 62.09 ? 12 VAL A O 1 ATOM 57 C CB . VAL A 1 11 ? -21.265 -23.872 83.642 1.00 61.25 ? 12 VAL A CB 1 ATOM 58 C CG1 . VAL A 1 11 ? -20.688 -22.691 82.865 1.00 54.76 ? 12 VAL A CG1 1 ATOM 59 C CG2 . VAL A 1 11 ? -20.715 -25.175 83.085 1.00 59.12 ? 12 VAL A CG2 1 ATOM 60 N N . ARG A 1 12 ? -22.682 -25.217 86.010 1.00 54.03 ? 13 ARG A N 1 ATOM 61 C CA . ARG A 1 12 ? -23.226 -26.350 86.763 1.00 55.91 ? 13 ARG A CA 1 ATOM 62 C C . ARG A 1 12 ? -22.554 -27.721 86.483 1.00 57.00 ? 13 ARG A C 1 ATOM 63 O O . ARG A 1 12 ? -22.485 -28.584 87.365 1.00 67.61 ? 13 ARG A O 1 ATOM 64 C CB . ARG A 1 12 ? -24.759 -26.418 86.586 1.00 53.96 ? 13 ARG A CB 1 ATOM 65 C CG . ARG A 1 12 ? -25.483 -27.508 87.394 1.00 66.76 ? 13 ARG A CG 1 ATOM 66 C CD . ARG A 1 12 ? -25.401 -27.266 88.902 1.00 69.01 ? 13 ARG A CD 1 ATOM 67 N NE . ARG A 1 12 ? -26.005 -25.988 89.275 1.00 77.86 ? 13 ARG A NE 1 ATOM 68 C CZ . ARG A 1 12 ? -25.716 -25.311 90.387 1.00 73.81 ? 13 ARG A CZ 1 ATOM 69 N NH1 . ARG A 1 12 ? -24.821 -25.780 91.251 1.00 78.60 ? 13 ARG A NH1 1 ATOM 70 N NH2 . ARG A 1 12 ? -26.314 -24.151 90.632 1.00 72.36 ? 13 ARG A NH2 1 ATOM 71 N N . GLY A 1 13 ? -22.044 -27.922 85.273 1.00 61.69 ? 14 GLY A N 1 ATOM 72 C CA . GLY A 1 13 ? -21.492 -29.216 84.919 1.00 58.15 ? 14 GLY A CA 1 ATOM 73 C C . GLY A 1 13 ? -19.986 -29.349 85.053 1.00 61.30 ? 14 GLY A C 1 ATOM 74 O O . GLY A 1 13 ? -19.445 -30.440 84.873 1.00 57.15 ? 14 GLY A O 1 ATOM 75 N N . GLY A 1 14 ? -19.304 -28.246 85.347 1.00 56.39 ? 15 GLY A N 1 ATOM 76 C CA . GLY A 1 14 ? -17.861 -28.274 85.490 1.00 58.06 ? 15 GLY A CA 1 ATOM 77 C C . GLY A 1 14 ? -17.175 -27.011 85.004 1.00 63.83 ? 15 GLY A C 1 ATOM 78 O O . GLY A 1 14 ? -17.822 -25.989 84.735 1.00 60.30 ? 15 GLY A O 1 ATOM 79 N N . ARG A 1 15 ? -15.853 -27.091 84.877 1.00 60.67 ? 16 ARG A N 1 ATOM 80 C CA . ARG A 1 15 ? -15.030 -25.932 84.538 1.00 64.92 ? 16 ARG A CA 1 ATOM 81 C C . ARG A 1 15 ? -14.817 -25.779 83.022 1.00 62.42 ? 16 ARG A C 1 ATOM 82 O O . ARG A 1 15 ? -14.811 -26.764 82.285 1.00 60.79 ? 16 ARG A O 1 ATOM 83 C CB . ARG A 1 15 ? -13.671 -26.025 85.260 1.00 69.23 ? 16 ARG A CB 1 ATOM 84 C CG . ARG A 1 15 ? -13.692 -25.679 86.770 1.00 68.24 ? 16 ARG A CG 1 ATOM 85 C CD . ARG A 1 15 ? -12.897 -26.686 87.618 1.00 68.62 ? 16 ARG A CD 1 ATOM 86 N NE . ARG A 1 15 ? -11.466 -26.727 87.310 1.00 73.94 ? 16 ARG A NE 1 ATOM 87 C CZ . ARG A 1 15 ? -10.702 -27.818 87.416 1.00 79.29 ? 16 ARG A CZ 1 ATOM 88 N NH1 . ARG A 1 15 ? -11.223 -28.974 87.818 1.00 75.37 ? 16 ARG A NH1 1 ATOM 89 N NH2 . ARG A 1 15 ? -9.411 -27.760 87.116 1.00 72.37 ? 16 ARG A NH2 1 ATOM 90 N N . LEU A 1 16 ? -14.630 -24.541 82.569 1.00 54.29 ? 17 LEU A N 1 ATOM 91 C CA . LEU A 1 16 ? -14.368 -24.275 81.158 1.00 67.88 ? 17 LEU A CA 1 ATOM 92 C C . LEU A 1 16 ? -13.148 -23.379 81.004 1.00 70.79 ? 17 LEU A C 1 ATOM 93 O O . LEU A 1 16 ? -12.868 -22.561 81.879 1.00 60.58 ? 17 LEU A O 1 ATOM 94 C CB . LEU A 1 16 ? -15.562 -23.567 80.490 1.00 62.16 ? 17 LEU A CB 1 ATOM 95 C CG . LEU A 1 16 ? -16.984 -24.089 80.669 1.00 56.69 ? 17 LEU A CG 1 ATOM 96 C CD1 . LEU A 1 16 ? -17.965 -23.104 80.058 1.00 53.44 ? 17 LEU A CD1 1 ATOM 97 C CD2 . LEU A 1 16 ? -17.143 -25.478 80.076 1.00 54.22 ? 17 LEU A CD2 1 ATOM 98 N N . ARG A 1 17 ? -12.463 -23.508 79.866 1.00 70.58 ? 18 ARG A N 1 ATOM 99 C CA . ARG A 1 17 ? -11.315 -22.668 79.535 1.00 66.81 ? 18 ARG A CA 1 ATOM 100 C C . ARG A 1 17 ? -11.551 -21.932 78.203 1.00 70.03 ? 18 ARG A C 1 ATOM 101 O O . ARG A 1 17 ? -11.452 -22.519 77.116 1.00 65.93 ? 18 ARG A O 1 ATOM 102 C CB . ARG A 1 17 ? -10.038 -23.521 79.474 1.00 70.89 ? 18 ARG A CB 1 ATOM 103 C CG . ARG A 1 17 ? -8.737 -22.738 79.320 1.00 75.73 ? 18 ARG A CG 1 ATOM 104 C CD . ARG A 1 17 ? -7.881 -23.287 78.178 1.00 79.41 ? 18 ARG A CD 1 ATOM 105 N NE . ARG A 1 17 ? -7.840 -24.753 78.157 1.00 89.77 ? 18 ARG A NE 1 ATOM 106 C CZ . ARG A 1 17 ? -7.276 -25.475 77.183 1.00 92.45 ? 18 ARG A CZ 1 ATOM 107 N NH1 . ARG A 1 17 ? -6.699 -24.866 76.148 1.00 90.97 ? 18 ARG A NH1 1 ATOM 108 N NH2 . ARG A 1 17 ? -7.289 -26.807 77.238 1.00 82.33 ? 18 ARG A NH2 1 ATOM 109 N N . GLY A 1 18 ? -11.863 -20.643 78.292 1.00 62.98 ? 19 GLY A N 1 ATOM 110 C CA . GLY A 1 18 ? -12.150 -19.839 77.118 1.00 62.54 ? 19 GLY A CA 1 ATOM 111 C C . GLY A 1 18 ? -10.946 -19.320 76.348 1.00 71.66 ? 19 GLY A C 1 ATOM 112 O O . GLY A 1 18 ? -9.815 -19.719 76.601 1.00 77.09 ? 19 GLY A O 1 ATOM 113 N N . ILE A 1 19 ? -11.203 -18.428 75.393 1.00 72.90 ? 20 ILE A N 1 ATOM 114 C CA . ILE A 1 19 ? -10.163 -17.811 74.574 1.00 68.29 ? 20 ILE A CA 1 ATOM 115 C C . ILE A 1 19 ? -10.539 -16.346 74.380 1.00 73.81 ? 20 ILE A C 1 ATOM 116 O O . ILE A 1 19 ? -11.724 -16.023 74.328 1.00 79.23 ? 20 ILE A O 1 ATOM 117 C CB . ILE A 1 19 ? -10.045 -18.512 73.203 1.00 69.66 ? 20 ILE A CB 1 ATOM 118 C CG1 . ILE A 1 19 ? -8.942 -17.883 72.360 1.00 71.55 ? 20 ILE A CG1 1 ATOM 119 C CG2 . ILE A 1 19 ? -11.362 -18.464 72.436 1.00 65.17 ? 20 ILE A CG2 1 ATOM 120 C CD1 . ILE A 1 19 ? -8.678 -18.645 71.074 1.00 68.17 ? 20 ILE A CD1 1 ATOM 121 N N . ARG A 1 20 ? -9.565 -15.444 74.316 1.00 71.66 ? 21 ARG A N 1 ATOM 122 C CA . ARG A 1 20 ? -9.921 -14.046 74.105 1.00 69.90 ? 21 ARG A CA 1 ATOM 123 C C . ARG A 1 20 ? -9.767 -13.688 72.637 1.00 74.23 ? 21 ARG A C 1 ATOM 124 O O . ARG A 1 20 ? -8.871 -14.184 71.955 1.00 78.44 ? 21 ARG A O 1 ATOM 125 C CB . ARG A 1 20 ? -9.177 -13.088 75.057 1.00 79.62 ? 21 ARG A CB 1 ATOM 126 C CG . ARG A 1 20 ? -7.934 -12.422 74.508 1.00 92.25 ? 21 ARG A CG 1 ATOM 127 C CD . ARG A 1 20 ? -7.455 -11.277 75.415 1.00 99.78 ? 21 ARG A CD 1 ATOM 128 N NE . ARG A 1 20 ? -6.063 -10.918 75.132 1.00 116.73 ? 21 ARG A NE 1 ATOM 129 C CZ . ARG A 1 20 ? -5.671 -10.155 74.112 1.00 123.71 ? 21 ARG A CZ 1 ATOM 130 N NH1 . ARG A 1 20 ? -6.564 -9.652 73.269 1.00 122.62 ? 21 ARG A NH1 1 ATOM 131 N NH2 . ARG A 1 20 ? -4.383 -9.895 73.932 1.00 125.96 ? 21 ARG A NH2 1 ATOM 132 N N . LEU A 1 21 ? -10.676 -12.859 72.139 1.00 77.98 ? 22 LEU A N 1 ATOM 133 C CA . LEU A 1 21 ? -10.703 -12.547 70.719 1.00 70.90 ? 22 LEU A CA 1 ATOM 134 C C . LEU A 1 21 ? -10.428 -11.073 70.480 1.00 72.83 ? 22 LEU A C 1 ATOM 135 O O . LEU A 1 21 ? -10.923 -10.216 71.209 1.00 76.84 ? 22 LEU A O 1 ATOM 136 C CB . LEU A 1 21 ? -12.054 -12.935 70.120 1.00 70.94 ? 22 LEU A CB 1 ATOM 137 C CG . LEU A 1 21 ? -12.440 -14.409 70.250 1.00 73.60 ? 22 LEU A CG 1 ATOM 138 C CD1 . LEU A 1 21 ? -13.730 -14.697 69.482 1.00 67.32 ? 22 LEU A CD1 1 ATOM 139 C CD2 . LEU A 1 21 ? -11.305 -15.304 69.773 1.00 63.99 ? 22 LEU A CD2 1 ATOM 140 N N . LYS A 1 22 ? -9.634 -10.787 69.455 1.00 74.25 ? 23 LYS A N 1 ATOM 141 C CA . LYS A 1 22 ? -9.296 -9.418 69.095 1.00 75.75 ? 23 LYS A CA 1 ATOM 142 C C . LYS A 1 22 ? -10.360 -8.804 68.187 1.00 74.35 ? 23 LYS A C 1 ATOM 143 O O . LYS A 1 22 ? -10.906 -9.473 67.313 1.00 72.10 ? 23 LYS A O 1 ATOM 144 C CB . LYS A 1 22 ? -7.928 -9.378 68.410 1.00 79.87 ? 23 LYS A CB 1 ATOM 145 C CG . LYS A 1 22 ? -6.793 -9.892 69.283 1.00 89.24 ? 23 LYS A CG 1 ATOM 146 C CD . LYS A 1 22 ? -5.542 -10.176 68.471 1.00 99.12 ? 23 LYS A CD 1 ATOM 147 C CE . LYS A 1 22 ? -4.477 -10.836 69.329 1.00 107.00 ? 23 LYS A CE 1 ATOM 148 N NZ . LYS A 1 22 ? -3.236 -11.114 68.560 1.00 107.30 ? 23 LYS A NZ 1 ATOM 149 N N . THR A 1 23 ? -10.683 -7.539 68.437 1.00 77.47 ? 24 THR A N 1 ATOM 150 C CA . THR A 1 23 ? -11.503 -6.737 67.535 1.00 76.79 ? 24 THR A CA 1 ATOM 151 C C . THR A 1 23 ? -10.989 -5.305 67.600 1.00 81.29 ? 24 THR A C 1 ATOM 152 O O . THR A 1 23 ? -10.488 -4.877 68.642 1.00 83.71 ? 24 THR A O 1 ATOM 153 C CB . THR A 1 23 ? -13.010 -6.700 67.923 1.00 75.43 ? 24 THR A CB 1 ATOM 154 O OG1 . THR A 1 23 ? -13.243 -5.649 68.872 1.00 84.37 ? 24 THR A OG1 1 ATOM 155 C CG2 . THR A 1 23 ? -13.490 -8.021 68.492 1.00 73.28 ? 24 THR A CG2 1 ATOM 156 N N . PRO A 1 24 ? -11.116 -4.559 66.489 1.00 82.53 ? 25 PRO A N 1 ATOM 157 C CA . PRO A 1 24 ? -10.787 -3.133 66.383 1.00 78.17 ? 25 PRO A CA 1 ATOM 158 C C . PRO A 1 24 ? -11.117 -2.262 67.603 1.00 88.09 ? 25 PRO A C 1 ATOM 159 O O . PRO A 1 24 ? -10.436 -1.262 67.813 1.00 93.53 ? 25 PRO A O 1 ATOM 160 C CB . PRO A 1 24 ? -11.622 -2.698 65.183 1.00 77.88 ? 25 PRO A CB 1 ATOM 161 C CG . PRO A 1 24 ? -11.551 -3.887 64.272 1.00 79.62 ? 25 PRO A CG 1 ATOM 162 C CD . PRO A 1 24 ? -11.492 -5.114 65.173 1.00 79.65 ? 25 PRO A CD 1 ATOM 163 N N . GLY A 1 25 ? -12.125 -2.625 68.390 1.00 84.73 ? 26 GLY A N 1 ATOM 164 C CA . GLY A 1 25 ? -12.514 -1.806 69.523 1.00 76.28 ? 26 GLY A CA 1 ATOM 165 C C . GLY A 1 25 ? -11.992 -2.308 70.858 1.00 84.22 ? 26 GLY A C 1 ATOM 166 O O . GLY A 1 25 ? -12.087 -1.619 71.878 1.00 82.86 ? 26 GLY A O 1 ATOM 167 N N . GLY A 1 26 ? -11.436 -3.513 70.862 1.00 79.23 ? 27 GLY A N 1 ATOM 168 C CA . GLY A 1 26 ? -10.997 -4.122 72.100 1.00 75.86 ? 27 GLY A CA 1 ATOM 169 C C . GLY A 1 26 ? -11.297 -5.604 72.138 1.00 78.00 ? 27 GLY A C 1 ATOM 170 O O . GLY A 1 26 ? -11.994 -6.122 71.271 1.00 78.69 ? 27 GLY A O 1 ATOM 171 N N . PRO A 1 27 ? -10.767 -6.301 73.151 1.00 83.22 ? 28 PRO A N 1 ATOM 172 C CA . PRO A 1 27 ? -10.949 -7.753 73.237 1.00 81.94 ? 28 PRO A CA 1 ATOM 173 C C . PRO A 1 27 ? -12.316 -8.188 73.775 1.00 76.89 ? 28 PRO A C 1 ATOM 174 O O . PRO A 1 27 ? -13.082 -7.403 74.351 1.00 71.97 ? 28 PRO A O 1 ATOM 175 C CB . PRO A 1 27 ? -9.823 -8.191 74.181 1.00 80.05 ? 28 PRO A CB 1 ATOM 176 C CG . PRO A 1 27 ? -9.590 -7.011 75.035 1.00 83.91 ? 28 PRO A CG 1 ATOM 177 C CD . PRO A 1 27 ? -9.866 -5.792 74.199 1.00 73.63 ? 28 PRO A CD 1 ATOM 178 N N . VAL A 1 28 ? -12.598 -9.469 73.572 1.00 72.69 ? 29 VAL A N 1 ATOM 179 C CA . VAL A 1 28 ? -13.846 -10.087 73.973 1.00 67.89 ? 29 VAL A CA 1 ATOM 180 C C . VAL A 1 28 ? -13.455 -11.475 74.448 1.00 64.77 ? 29 VAL A C 1 ATOM 181 O O . VAL A 1 28 ? -12.478 -12.040 73.955 1.00 66.67 ? 29 VAL A O 1 ATOM 182 C CB . VAL A 1 28 ? -14.819 -10.184 72.757 1.00 72.08 ? 29 VAL A CB 1 ATOM 183 C CG1 . VAL A 1 28 ? -15.927 -11.190 73.005 1.00 67.80 ? 29 VAL A CG1 1 ATOM 184 C CG2 . VAL A 1 28 ? -15.406 -8.814 72.416 1.00 59.00 ? 29 VAL A CG2 1 ATOM 185 N N . SER A 1 29 ? -14.187 -12.011 75.421 1.00 61.02 ? 30 SER A N 1 ATOM 186 C CA . SER A 1 29 ? -13.951 -13.375 75.900 1.00 68.07 ? 30 SER A CA 1 ATOM 187 C C . SER A 1 29 ? -14.944 -14.344 75.261 1.00 64.19 ? 30 SER A C 1 ATOM 188 O O . SER A 1 29 ? -16.148 -14.076 75.215 1.00 63.50 ? 30 SER A O 1 ATOM 189 C CB . SER A 1 29 ? -14.059 -13.461 77.437 1.00 64.11 ? 30 SER A CB 1 ATOM 190 O OG . SER A 1 29 ? -13.156 -12.576 78.078 1.00 73.53 ? 30 SER A OG 1 ATOM 191 N N . ALA A 1 30 ? -14.444 -15.479 74.788 1.00 61.09 ? 31 ALA A N 1 ATOM 192 C CA . ALA A 1 30 ? -15.288 -16.413 74.051 1.00 64.36 ? 31 ALA A CA 1 ATOM 193 C C . ALA A 1 30 ? -15.178 -17.799 74.636 1.00 62.80 ? 31 ALA A C 1 ATOM 194 O O . ALA A 1 30 ? -14.093 -18.241 75.013 1.00 61.84 ? 31 ALA A O 1 ATOM 195 C CB . ALA A 1 30 ? -14.913 -16.427 72.556 1.00 60.71 ? 31 ALA A CB 1 ATOM 196 N N . PHE A 1 31 ? -16.310 -18.483 74.714 1.00 56.41 ? 32 PHE A N 1 ATOM 197 C CA . PHE A 1 31 ? -16.329 -19.849 75.200 1.00 60.25 ? 32 PHE A CA 1 ATOM 198 C C . PHE A 1 31 ? -17.053 -20.704 74.158 1.00 57.81 ? 32 PHE A C 1 ATOM 199 O O . PHE A 1 31 ? -18.281 -20.681 74.063 1.00 56.49 ? 32 PHE A O 1 ATOM 200 C CB . PHE A 1 31 ? -17.006 -19.923 76.577 1.00 60.40 ? 32 PHE A CB 1 ATOM 201 C CG . PHE A 1 31 ? -16.295 -19.126 77.668 1.00 61.69 ? 32 PHE A CG 1 ATOM 202 C CD1 . PHE A 1 31 ? -16.542 -17.768 77.840 1.00 60.23 ? 32 PHE A CD1 1 ATOM 203 C CD2 . PHE A 1 31 ? -15.406 -19.745 78.537 1.00 63.75 ? 32 PHE A CD2 1 ATOM 204 C CE1 . PHE A 1 31 ? -15.902 -17.043 78.843 1.00 62.80 ? 32 PHE A CE1 1 ATOM 205 C CE2 . PHE A 1 31 ? -14.766 -19.022 79.547 1.00 66.21 ? 32 PHE A CE2 1 ATOM 206 C CZ . PHE A 1 31 ? -15.012 -17.671 79.695 1.00 60.20 ? 32 PHE A CZ 1 ATOM 207 N N . LEU A 1 32 ? -16.276 -21.445 73.374 1.00 50.62 ? 33 LEU A N 1 ATOM 208 C CA . LEU A 1 32 ? -16.783 -22.126 72.189 1.00 52.78 ? 33 LEU A CA 1 ATOM 209 C C . LEU A 1 32 ? -16.870 -23.635 72.359 1.00 57.45 ? 33 LEU A C 1 ATOM 210 O O . LEU A 1 32 ? -15.927 -24.274 72.832 1.00 63.63 ? 33 LEU A O 1 ATOM 211 C CB . LEU A 1 32 ? -15.895 -21.800 70.984 1.00 55.51 ? 33 LEU A CB 1 ATOM 212 C CG . LEU A 1 32 ? -15.574 -20.315 70.834 1.00 55.37 ? 33 LEU A CG 1 ATOM 213 C CD1 . LEU A 1 32 ? -14.691 -20.083 69.633 1.00 52.43 ? 33 LEU A CD1 1 ATOM 214 C CD2 . LEU A 1 32 ? -16.847 -19.474 70.759 1.00 54.61 ? 33 LEU A CD2 1 ATOM 215 N N . GLY A 1 33 ? -18.007 -24.206 71.971 1.00 51.26 ? 34 GLY A N 1 ATOM 216 C CA . GLY A 1 33 ? -18.159 -25.652 71.977 1.00 53.94 ? 34 GLY A CA 1 ATOM 217 C C . GLY A 1 33 ? -18.315 -26.247 73.369 1.00 56.44 ? 34 GLY A C 1 ATOM 218 O O . GLY A 1 33 ? -17.633 -27.229 73.724 1.00 53.14 ? 34 GLY A O 1 ATOM 219 N N . ILE A 1 34 ? -19.215 -25.648 74.151 1.00 47.83 ? 35 ILE A N 1 ATOM 220 C CA . ILE A 1 34 ? -19.612 -26.185 75.433 1.00 46.69 ? 35 ILE A CA 1 ATOM 221 C C . ILE A 1 34 ? -20.703 -27.211 75.204 1.00 50.81 ? 35 ILE A C 1 ATOM 222 O O . ILE A 1 34 ? -21.730 -26.881 74.611 1.00 53.11 ? 35 ILE A O 1 ATOM 223 C CB . ILE A 1 34 ? -20.217 -25.077 76.336 1.00 55.84 ? 35 ILE A CB 1 ATOM 224 C CG1 . ILE A 1 34 ? -19.272 -23.874 76.442 1.00 51.33 ? 35 ILE A CG1 1 ATOM 225 C CG2 . ILE A 1 34 ? -20.605 -25.649 77.711 1.00 40.44 ? 35 ILE A CG2 1 ATOM 226 C CD1 . ILE A 1 34 ? -19.932 -22.642 77.002 1.00 44.78 ? 35 ILE A CD1 1 ATOM 227 N N . PRO A 1 35 ? -20.506 -28.450 75.687 1.00 51.43 ? 36 PRO A N 1 ATOM 228 C CA . PRO A 1 35 ? -21.552 -29.477 75.582 1.00 48.83 ? 36 PRO A CA 1 ATOM 229 C C . PRO A 1 35 ? -22.767 -29.134 76.423 1.00 50.09 ? 36 PRO A C 1 ATOM 230 O O . PRO A 1 35 ? -22.590 -28.783 77.587 1.00 57.81 ? 36 PRO A O 1 ATOM 231 C CB . PRO A 1 35 ? -20.871 -30.728 76.136 1.00 47.02 ? 36 PRO A CB 1 ATOM 232 C CG . PRO A 1 35 ? -19.792 -30.205 77.039 1.00 51.09 ? 36 PRO A CG 1 ATOM 233 C CD . PRO A 1 35 ? -19.301 -28.961 76.360 1.00 59.52 ? 36 PRO A CD 1 ATOM 234 N N . PHE A 1 36 ? -23.967 -29.216 75.846 1.00 51.07 ? 37 PHE A N 1 ATOM 235 C CA . PHE A 1 36 ? -25.193 -29.004 76.611 1.00 43.22 ? 37 PHE A CA 1 ATOM 236 C C . PHE A 1 36 ? -26.123 -30.213 76.613 1.00 51.89 ? 37 PHE A C 1 ATOM 237 O O . PHE A 1 36 ? -27.202 -30.181 77.213 1.00 49.75 ? 37 PHE A O 1 ATOM 238 C CB . PHE A 1 36 ? -25.941 -27.746 76.167 1.00 45.77 ? 37 PHE A CB 1 ATOM 239 C CG . PHE A 1 36 ? -26.566 -27.835 74.795 1.00 46.68 ? 37 PHE A CG 1 ATOM 240 C CD1 . PHE A 1 36 ? -27.818 -28.403 74.619 1.00 47.58 ? 37 PHE A CD1 1 ATOM 241 C CD2 . PHE A 1 36 ? -25.923 -27.285 73.692 1.00 51.40 ? 37 PHE A CD2 1 ATOM 242 C CE1 . PHE A 1 36 ? -28.414 -28.453 73.359 1.00 48.59 ? 37 PHE A CE1 1 ATOM 243 C CE2 . PHE A 1 36 ? -26.497 -27.333 72.432 1.00 50.49 ? 37 PHE A CE2 1 ATOM 244 C CZ . PHE A 1 36 ? -27.749 -27.920 72.261 1.00 50.80 ? 37 PHE A CZ 1 ATOM 245 N N . ALA A 1 37 ? -25.702 -31.281 75.947 1.00 52.72 ? 38 ALA A N 1 ATOM 246 C CA . ALA A 1 37 ? -26.523 -32.479 75.857 1.00 49.80 ? 38 ALA A CA 1 ATOM 247 C C . ALA A 1 37 ? -25.644 -33.718 75.794 1.00 52.29 ? 38 ALA A C 1 ATOM 248 O O . ALA A 1 37 ? -24.469 -33.639 75.440 1.00 55.77 ? 38 ALA A O 1 ATOM 249 C CB . ALA A 1 37 ? -27.461 -32.398 74.622 1.00 45.18 ? 38 ALA A CB 1 ATOM 250 N N . GLU A 1 38 ? -26.205 -34.861 76.166 1.00 53.48 ? 39 GLU A N 1 ATOM 251 C CA . GLU A 1 38 ? -25.539 -36.132 75.921 1.00 53.78 ? 39 GLU A CA 1 ATOM 252 C C . GLU A 1 38 ? -25.630 -36.350 74.417 1.00 64.94 ? 39 GLU A C 1 ATOM 253 O O . GLU A 1 38 ? -26.722 -36.220 73.841 1.00 63.82 ? 39 GLU A O 1 ATOM 254 C CB . GLU A 1 38 ? -26.243 -37.272 76.675 1.00 57.24 ? 39 GLU A CB 1 ATOM 255 C CG . GLU A 1 38 ? -25.956 -37.321 78.181 1.00 62.87 ? 39 GLU A CG 1 ATOM 256 C CD . GLU A 1 38 ? -24.457 -37.363 78.499 1.00 71.84 ? 39 GLU A CD 1 ATOM 257 O OE1 . GLU A 1 38 ? -23.744 -38.237 77.956 1.00 71.30 ? 39 GLU A OE1 1 ATOM 258 O OE2 . GLU A 1 38 ? -23.987 -36.503 79.279 1.00 69.35 ? 39 GLU A OE2 1 ATOM 259 N N . PRO A 1 39 ? -24.490 -36.658 73.772 1.00 68.59 ? 40 PRO A N 1 ATOM 260 C CA . PRO A 1 39 ? -24.418 -36.800 72.310 1.00 64.26 ? 40 PRO A CA 1 ATOM 261 C C . PRO A 1 39 ? -25.478 -37.760 71.790 1.00 58.00 ? 40 PRO A C 1 ATOM 262 O O . PRO A 1 39 ? -25.588 -38.882 72.276 1.00 62.01 ? 40 PRO A O 1 ATOM 263 C CB . PRO A 1 39 ? -23.006 -37.354 72.071 1.00 59.76 ? 40 PRO A CB 1 ATOM 264 C CG . PRO A 1 39 ? -22.527 -37.814 73.396 1.00 57.03 ? 40 PRO A CG 1 ATOM 265 C CD . PRO A 1 39 ? -23.199 -36.953 74.410 1.00 60.58 ? 40 PRO A CD 1 ATOM 266 N N . PRO A 1 40 ? -26.276 -37.305 70.821 1.00 57.62 ? 41 PRO A N 1 ATOM 267 C CA . PRO A 1 40 ? -27.432 -38.078 70.373 1.00 63.16 ? 41 PRO A CA 1 ATOM 268 C C . PRO A 1 40 ? -27.063 -39.088 69.292 1.00 63.70 ? 41 PRO A C 1 ATOM 269 O O . PRO A 1 40 ? -27.539 -38.947 68.177 1.00 64.57 ? 41 PRO A O 1 ATOM 270 C CB . PRO A 1 40 ? -28.349 -37.005 69.782 1.00 59.35 ? 41 PRO A CB 1 ATOM 271 C CG . PRO A 1 40 ? -27.485 -35.750 69.621 1.00 56.35 ? 41 PRO A CG 1 ATOM 272 C CD . PRO A 1 40 ? -26.089 -36.098 70.005 1.00 57.03 ? 41 PRO A CD 1 ATOM 273 N N . MET A 1 41 ? -26.229 -40.074 69.617 1.00 63.57 ? 42 MET A N 1 ATOM 274 C CA . MET A 1 41 ? -25.844 -41.107 68.664 1.00 67.88 ? 42 MET A CA 1 ATOM 275 C C . MET A 1 41 ? -26.558 -42.382 69.028 1.00 70.96 ? 42 MET A C 1 ATOM 276 O O . MET A 1 41 ? -27.349 -42.405 69.968 1.00 73.99 ? 42 MET A O 1 ATOM 277 C CB . MET A 1 41 ? -24.347 -41.405 68.726 1.00 68.57 ? 42 MET A CB 1 ATOM 278 C CG . MET A 1 41 ? -23.499 -40.321 69.301 1.00 70.68 ? 42 MET A CG 1 ATOM 279 S SD . MET A 1 41 ? -22.462 -39.589 68.046 1.00 88.41 ? 42 MET A SD 1 ATOM 280 C CE . MET A 1 41 ? -21.582 -41.028 67.431 1.00 84.49 ? 42 MET A CE 1 ATOM 281 N N . GLY A 1 42 ? -26.243 -43.446 68.292 1.00 61.87 ? 43 GLY A N 1 ATOM 282 C CA . GLY A 1 42 ? -26.692 -44.788 68.617 1.00 65.05 ? 43 GLY A CA 1 ATOM 283 C C . GLY A 1 42 ? -28.181 -44.906 68.868 1.00 66.44 ? 43 GLY A C 1 ATOM 284 O O . GLY A 1 42 ? -28.998 -44.516 68.034 1.00 68.87 ? 43 GLY A O 1 ATOM 285 N N . PRO A 1 43 ? -28.548 -45.426 70.042 1.00 66.20 ? 44 PRO A N 1 ATOM 286 C CA . PRO A 1 43 ? -29.960 -45.645 70.371 1.00 64.84 ? 44 PRO A CA 1 ATOM 287 C C . PRO A 1 43 ? -30.681 -44.342 70.679 1.00 61.91 ? 44 PRO A C 1 ATOM 288 O O . PRO A 1 43 ? -31.902 -44.334 70.860 1.00 61.86 ? 44 PRO A O 1 ATOM 289 C CB . PRO A 1 43 ? -29.896 -46.543 71.610 1.00 57.53 ? 44 PRO A CB 1 ATOM 290 C CG . PRO A 1 43 ? -28.565 -46.270 72.216 1.00 54.69 ? 44 PRO A CG 1 ATOM 291 C CD . PRO A 1 43 ? -27.639 -45.870 71.110 1.00 59.72 ? 44 PRO A CD 1 ATOM 292 N N . ARG A 1 44 ? -29.926 -43.251 70.732 1.00 61.09 ? 45 ARG A N 1 ATOM 293 C CA . ARG A 1 44 ? -30.499 -41.946 71.018 1.00 60.68 ? 45 ARG A CA 1 ATOM 294 C C . ARG A 1 44 ? -30.817 -41.141 69.768 1.00 64.98 ? 45 ARG A C 1 ATOM 295 O O . ARG A 1 44 ? -31.428 -40.072 69.872 1.00 63.43 ? 45 ARG A O 1 ATOM 296 C CB . ARG A 1 44 ? -29.561 -41.133 71.896 1.00 71.19 ? 45 ARG A CB 1 ATOM 297 C CG . ARG A 1 44 ? -29.588 -41.490 73.361 1.00 65.09 ? 45 ARG A CG 1 ATOM 298 C CD . ARG A 1 44 ? -28.440 -40.800 74.032 1.00 62.39 ? 45 ARG A CD 1 ATOM 299 N NE . ARG A 1 44 ? -28.650 -40.653 75.469 1.00 86.63 ? 45 ARG A NE 1 ATOM 300 C CZ . ARG A 1 44 ? -28.255 -41.534 76.383 1.00 83.03 ? 45 ARG A CZ 1 ATOM 301 N NH1 . ARG A 1 44 ? -27.636 -42.650 76.015 1.00 75.80 ? 45 ARG A NH1 1 ATOM 302 N NH2 . ARG A 1 44 ? -28.488 -41.299 77.668 1.00 91.64 ? 45 ARG A NH2 1 ATOM 303 N N . ARG A 1 45 ? -30.396 -41.625 68.596 1.00 63.39 ? 46 ARG A N 1 ATOM 304 C CA . ARG A 1 45 ? -30.735 -40.935 67.362 1.00 52.62 ? 46 ARG A CA 1 ATOM 305 C C . ARG A 1 45 ? -32.255 -40.792 67.338 1.00 56.57 ? 46 ARG A C 1 ATOM 306 O O . ARG A 1 45 ? -32.981 -41.700 67.765 1.00 53.87 ? 46 ARG A O 1 ATOM 307 C CB . ARG A 1 45 ? -30.215 -41.681 66.121 1.00 59.20 ? 46 ARG A CB 1 ATOM 308 C CG . ARG A 1 45 ? -30.591 -41.009 64.780 1.00 52.13 ? 46 ARG A CG 1 ATOM 309 C CD . ARG A 1 45 ? -30.261 -41.882 63.562 1.00 61.80 ? 46 ARG A CD 1 ATOM 310 N NE . ARG A 1 45 ? -28.838 -41.904 63.216 1.00 59.94 ? 46 ARG A NE 1 ATOM 311 C CZ . ARG A 1 45 ? -28.280 -42.783 62.386 1.00 57.74 ? 46 ARG A CZ 1 ATOM 312 N NH1 . ARG A 1 45 ? -29.018 -43.725 61.815 1.00 59.60 ? 46 ARG A NH1 1 ATOM 313 N NH2 . ARG A 1 45 ? -26.980 -42.733 62.134 1.00 51.05 ? 46 ARG A NH2 1 ATOM 314 N N . PHE A 1 46 ? -32.715 -39.623 66.902 1.00 54.87 ? 47 PHE A N 1 ATOM 315 C CA . PHE A 1 46 ? -34.136 -39.310 66.796 1.00 53.46 ? 47 PHE A CA 1 ATOM 316 C C . PHE A 1 46 ? -34.832 -38.968 68.124 1.00 50.21 ? 47 PHE A C 1 ATOM 317 O O . PHE A 1 46 ? -35.915 -38.399 68.102 1.00 52.53 ? 47 PHE A O 1 ATOM 318 C CB . PHE A 1 46 ? -34.910 -40.418 66.064 1.00 56.06 ? 47 PHE A CB 1 ATOM 319 C CG . PHE A 1 46 ? -34.386 -40.738 64.690 1.00 56.10 ? 47 PHE A CG 1 ATOM 320 C CD1 . PHE A 1 46 ? -34.119 -39.728 63.774 1.00 63.62 ? 47 PHE A CD1 1 ATOM 321 C CD2 . PHE A 1 46 ? -34.172 -42.062 64.302 1.00 61.25 ? 47 PHE A CD2 1 ATOM 322 C CE1 . PHE A 1 46 ? -33.644 -40.031 62.482 1.00 53.95 ? 47 PHE A CE1 1 ATOM 323 C CE2 . PHE A 1 46 ? -33.708 -42.373 63.013 1.00 57.13 ? 47 PHE A CE2 1 ATOM 324 C CZ . PHE A 1 46 ? -33.446 -41.358 62.111 1.00 49.93 ? 47 PHE A CZ 1 ATOM 325 N N . LEU A 1 47 ? -34.231 -39.297 69.270 1.00 48.05 ? 48 LEU A N 1 ATOM 326 C CA . LEU A 1 47 ? -34.877 -38.993 70.560 1.00 56.72 ? 48 LEU A CA 1 ATOM 327 C C . LEU A 1 47 ? -34.718 -37.537 70.999 1.00 50.36 ? 48 LEU A C 1 ATOM 328 O O . LEU A 1 47 ? -33.792 -36.844 70.557 1.00 46.54 ? 48 LEU A O 1 ATOM 329 C CB . LEU A 1 47 ? -34.398 -39.934 71.681 1.00 51.92 ? 48 LEU A CB 1 ATOM 330 C CG . LEU A 1 47 ? -34.750 -41.415 71.518 1.00 52.90 ? 48 LEU A CG 1 ATOM 331 C CD1 . LEU A 1 47 ? -34.198 -42.193 72.674 1.00 45.29 ? 48 LEU A CD1 1 ATOM 332 C CD2 . LEU A 1 47 ? -36.247 -41.640 71.377 1.00 43.61 ? 48 LEU A CD2 1 ATOM 333 N N . PRO A 1 48 ? -35.632 -37.064 71.863 1.00 51.50 ? 49 PRO A N 1 ATOM 334 C CA . PRO A 1 48 ? -35.404 -35.770 72.530 1.00 52.69 ? 49 PRO A CA 1 ATOM 335 C C . PRO A 1 48 ? -34.021 -35.774 73.208 1.00 51.62 ? 49 PRO A C 1 ATOM 336 O O . PRO A 1 48 ? -33.553 -36.839 73.623 1.00 54.27 ? 49 PRO A O 1 ATOM 337 C CB . PRO A 1 48 ? -36.526 -35.711 73.570 1.00 43.82 ? 49 PRO A CB 1 ATOM 338 C CG . PRO A 1 48 ? -37.617 -36.564 72.999 1.00 48.27 ? 49 PRO A CG 1 ATOM 339 C CD . PRO A 1 48 ? -36.922 -37.675 72.247 1.00 46.42 ? 49 PRO A CD 1 ATOM 340 N N . PRO A 1 49 ? -33.356 -34.610 73.284 1.00 45.49 ? 50 PRO A N 1 ATOM 341 C CA . PRO A 1 49 ? -32.014 -34.564 73.862 1.00 47.09 ? 50 PRO A CA 1 ATOM 342 C C . PRO A 1 49 ? -32.042 -34.792 75.379 1.00 51.13 ? 50 PRO A C 1 ATOM 343 O O . PRO A 1 49 ? -33.022 -34.441 76.038 1.00 47.75 ? 50 PRO A O 1 ATOM 344 C CB . PRO A 1 49 ? -31.576 -33.132 73.566 1.00 43.77 ? 50 PRO A CB 1 ATOM 345 C CG . PRO A 1 49 ? -32.819 -32.369 73.616 1.00 44.74 ? 50 PRO A CG 1 ATOM 346 C CD . PRO A 1 49 ? -33.858 -33.262 72.981 1.00 47.20 ? 50 PRO A CD 1 ATOM 347 N N . GLU A 1 50 ? -30.984 -35.393 75.912 1.00 58.65 ? 51 GLU A N 1 ATOM 348 C CA . GLU A 1 50 ? -30.795 -35.512 77.361 1.00 52.59 ? 51 GLU A CA 1 ATOM 349 C C . GLU A 1 50 ? -29.708 -34.541 77.797 1.00 55.34 ? 51 GLU A C 1 ATOM 350 O O . GLU A 1 50 ? -28.743 -34.321 77.067 1.00 48.82 ? 51 GLU A O 1 ATOM 351 C CB . GLU A 1 50 ? -30.415 -36.942 77.750 1.00 47.25 ? 51 GLU A CB 1 ATOM 352 C CG . GLU A 1 50 ? -31.619 -37.825 78.081 1.00 68.61 ? 51 GLU A CG 1 ATOM 353 C CD . GLU A 1 50 ? -31.407 -39.297 77.705 1.00 90.37 ? 51 GLU A CD 1 ATOM 354 O OE1 . GLU A 1 50 ? -30.970 -40.081 78.582 1.00 91.07 ? 51 GLU A OE1 1 ATOM 355 O OE2 . GLU A 1 50 ? -31.690 -39.667 76.533 1.00 91.39 ? 51 GLU A OE2 1 ATOM 356 N N . PRO A 1 51 ? -29.856 -33.952 78.998 1.00 57.84 ? 52 PRO A N 1 ATOM 357 C CA . PRO A 1 51 ? -28.884 -32.953 79.461 1.00 48.96 ? 52 PRO A CA 1 ATOM 358 C C . PRO A 1 51 ? -27.490 -33.542 79.662 1.00 44.58 ? 52 PRO A C 1 ATOM 359 O O . PRO A 1 51 ? -27.370 -34.690 80.061 1.00 49.21 ? 52 PRO A O 1 ATOM 360 C CB . PRO A 1 51 ? -29.474 -32.477 80.781 1.00 47.16 ? 52 PRO A CB 1 ATOM 361 C CG . PRO A 1 51 ? -30.925 -32.827 80.716 1.00 52.74 ? 52 PRO A CG 1 ATOM 362 C CD . PRO A 1 51 ? -30.974 -34.109 79.940 1.00 52.82 ? 52 PRO A CD 1 ATOM 363 N N . LYS A 1 52 ? -26.456 -32.773 79.334 1.00 48.67 ? 53 LYS A N 1 ATOM 364 C CA . LYS A 1 52 ? -25.074 -33.198 79.527 1.00 51.94 ? 53 LYS A CA 1 ATOM 365 C C . LYS A 1 52 ? -24.837 -33.523 81.017 1.00 62.30 ? 53 LYS A C 1 ATOM 366 O O . LYS A 1 52 ? -25.270 -32.781 81.900 1.00 54.07 ? 53 LYS A O 1 ATOM 367 C CB . LYS A 1 52 ? -24.124 -32.088 79.052 1.00 47.49 ? 53 LYS A CB 1 ATOM 368 C CG . LYS A 1 52 ? -22.624 -32.400 79.175 1.00 53.11 ? 53 LYS A CG 1 ATOM 369 C CD . LYS A 1 52 ? -22.262 -33.709 78.476 1.00 53.22 ? 53 LYS A CD 1 ATOM 370 C CE . LYS A 1 52 ? -20.757 -33.875 78.308 1.00 44.82 ? 53 LYS A CE 1 ATOM 371 N NZ . LYS A 1 52 ? -20.408 -35.265 77.851 1.00 52.78 ? 53 LYS A NZ 1 ATOM 372 N N . GLN A 1 53 ? -24.181 -34.649 81.289 1.00 63.82 ? 54 GLN A N 1 ATOM 373 C CA . GLN A 1 53 ? -23.855 -35.053 82.655 1.00 63.47 ? 54 GLN A CA 1 ATOM 374 C C . GLN A 1 53 ? -22.621 -34.280 83.099 1.00 61.52 ? 54 GLN A C 1 ATOM 375 O O . GLN A 1 53 ? -21.783 -33.934 82.254 1.00 61.59 ? 54 GLN A O 1 ATOM 376 C CB . GLN A 1 53 ? -23.613 -36.569 82.727 1.00 62.09 ? 54 GLN A CB 1 ATOM 377 C CG . GLN A 1 53 ? -24.835 -37.394 82.312 1.00 78.12 ? 54 GLN A CG 1 ATOM 378 C CD . GLN A 1 53 ? -24.692 -38.879 82.599 1.00 89.59 ? 54 GLN A CD 1 ATOM 379 O OE1 . GLN A 1 53 ? -25.028 -39.723 81.758 1.00 85.69 ? 54 GLN A OE1 1 ATOM 380 N NE2 . GLN A 1 53 ? -24.211 -39.207 83.799 1.00 99.45 ? 54 GLN A NE2 1 ATOM 381 N N . PRO A 1 54 ? -22.510 -33.991 84.415 1.00 61.45 ? 55 PRO A N 1 ATOM 382 C CA . PRO A 1 54 ? -21.375 -33.232 84.966 1.00 61.11 ? 55 PRO A CA 1 ATOM 383 C C . PRO A 1 54 ? -20.037 -33.891 84.622 1.00 56.82 ? 55 PRO A C 1 ATOM 384 O O . PRO A 1 54 ? -19.934 -35.120 84.623 1.00 53.99 ? 55 PRO A O 1 ATOM 385 C CB . PRO A 1 54 ? -21.606 -33.297 86.492 1.00 53.71 ? 55 PRO A CB 1 ATOM 386 C CG . PRO A 1 54 ? -23.008 -33.650 86.677 1.00 51.23 ? 55 PRO A CG 1 ATOM 387 C CD . PRO A 1 54 ? -23.412 -34.474 85.479 1.00 63.96 ? 55 PRO A CD 1 ATOM 388 N N . TRP A 1 55 ? -19.024 -33.088 84.327 1.00 57.02 ? 56 TRP A N 1 ATOM 389 C CA . TRP A 1 55 ? -17.715 -33.637 83.982 1.00 61.67 ? 56 TRP A CA 1 ATOM 390 C C . TRP A 1 55 ? -16.619 -33.279 84.998 1.00 66.83 ? 56 TRP A C 1 ATOM 391 O O . TRP A 1 55 ? -16.650 -32.224 85.643 1.00 72.22 ? 56 TRP A O 1 ATOM 392 C CB . TRP A 1 55 ? -17.301 -33.192 82.569 1.00 59.01 ? 56 TRP A CB 1 ATOM 393 C CG . TRP A 1 55 ? -17.142 -31.707 82.417 1.00 60.76 ? 56 TRP A CG 1 ATOM 394 C CD1 . TRP A 1 55 ? -16.011 -30.976 82.640 1.00 63.30 ? 56 TRP A CD1 1 ATOM 395 C CD2 . TRP A 1 55 ? -18.145 -30.771 81.991 1.00 60.18 ? 56 TRP A CD2 1 ATOM 396 N NE1 . TRP A 1 55 ? -16.249 -29.641 82.399 1.00 62.22 ? 56 TRP A NE1 1 ATOM 397 C CE2 . TRP A 1 55 ? -17.552 -29.490 81.997 1.00 62.22 ? 56 TRP A CE2 1 ATOM 398 C CE3 . TRP A 1 55 ? -19.485 -30.891 81.613 1.00 46.47 ? 56 TRP A CE3 1 ATOM 399 C CZ2 . TRP A 1 55 ? -18.255 -28.341 81.636 1.00 54.96 ? 56 TRP A CZ2 1 ATOM 400 C CZ3 . TRP A 1 55 ? -20.181 -29.751 81.280 1.00 46.93 ? 56 TRP A CZ3 1 ATOM 401 C CH2 . TRP A 1 55 ? -19.563 -28.492 81.284 1.00 51.64 ? 56 TRP A CH2 1 ATOM 402 N N . SER A 1 56 ? -15.644 -34.164 85.144 1.00 66.93 ? 57 SER A N 1 ATOM 403 C CA . SER A 1 56 ? -14.466 -33.819 85.921 1.00 77.91 ? 57 SER A CA 1 ATOM 404 C C . SER A 1 56 ? -13.462 -33.164 84.978 1.00 78.67 ? 57 SER A C 1 ATOM 405 O O . SER A 1 56 ? -13.408 -33.500 83.795 1.00 79.84 ? 57 SER A O 1 ATOM 406 C CB . SER A 1 56 ? -13.865 -35.063 86.564 1.00 73.43 ? 57 SER A CB 1 ATOM 407 O OG . SER A 1 56 ? -13.590 -36.044 85.577 1.00 78.78 ? 57 SER A OG 1 ATOM 408 N N . GLY A 1 57 ? -12.686 -32.215 85.491 1.00 76.71 ? 58 GLY A N 1 ATOM 409 C CA . GLY A 1 57 ? -11.653 -31.583 84.696 1.00 74.29 ? 58 GLY A CA 1 ATOM 410 C C . GLY A 1 57 ? -12.075 -30.274 84.057 1.00 72.09 ? 58 GLY A C 1 ATOM 411 O O . GLY A 1 57 ? -13.100 -29.695 84.420 1.00 72.54 ? 58 GLY A O 1 ATOM 412 N N . VAL A 1 58 ? -11.264 -29.799 83.116 1.00 61.86 ? 59 VAL A N 1 ATOM 413 C CA . VAL A 1 58 ? -11.542 -28.549 82.425 1.00 65.49 ? 59 VAL A CA 1 ATOM 414 C C . VAL A 1 58 ? -11.819 -28.811 80.962 1.00 63.68 ? 59 VAL A C 1 ATOM 415 O O . VAL A 1 58 ? -11.018 -29.454 80.281 1.00 54.79 ? 59 VAL A O 1 ATOM 416 C CB . VAL A 1 58 ? -10.366 -27.561 82.517 1.00 66.31 ? 59 VAL A CB 1 ATOM 417 C CG1 . VAL A 1 58 ? -10.701 -26.284 81.770 1.00 63.39 ? 59 VAL A CG1 1 ATOM 418 C CG2 . VAL A 1 58 ? -10.057 -27.248 83.970 1.00 71.80 ? 59 VAL A CG2 1 ATOM 419 N N . VAL A 1 59 ? -12.960 -28.317 80.485 1.00 69.23 ? 60 VAL A N 1 ATOM 420 C CA . VAL A 1 59 ? -13.314 -28.452 79.076 1.00 66.40 ? 60 VAL A CA 1 ATOM 421 C C . VAL A 1 59 ? -12.645 -27.358 78.252 1.00 66.15 ? 60 VAL A C 1 ATOM 422 O O . VAL A 1 59 ? -12.725 -26.170 78.593 1.00 65.77 ? 60 VAL A O 1 ATOM 423 C CB . VAL A 1 59 ? -14.855 -28.458 78.844 1.00 66.28 ? 60 VAL A CB 1 ATOM 424 C CG1 . VAL A 1 59 ? -15.194 -28.258 77.351 1.00 65.26 ? 60 VAL A CG1 1 ATOM 425 C CG2 . VAL A 1 59 ? -15.444 -29.756 79.306 1.00 59.28 ? 60 VAL A CG2 1 ATOM 426 N N . ASP A 1 60 ? -11.968 -27.780 77.184 1.00 63.60 ? 61 ASP A N 1 ATOM 427 C CA . ASP A 1 60 ? -11.389 -26.866 76.204 1.00 70.86 ? 61 ASP A CA 1 ATOM 428 C C . ASP A 1 60 ? -12.491 -26.186 75.391 1.00 67.60 ? 61 ASP A C 1 ATOM 429 O O . ASP A 1 60 ? -13.072 -26.786 74.490 1.00 77.15 ? 61 ASP A O 1 ATOM 430 C CB . ASP A 1 60 ? -10.430 -27.615 75.263 1.00 70.31 ? 61 ASP A CB 1 ATOM 431 C CG . ASP A 1 60 ? -9.794 -26.699 74.223 1.00 84.00 ? 61 ASP A CG 1 ATOM 432 O OD1 . ASP A 1 60 ? -9.286 -25.626 74.614 1.00 82.63 ? 61 ASP A OD1 1 ATOM 433 O OD2 . ASP A 1 60 ? -9.811 -27.037 73.013 1.00 90.09 ? 61 ASP A OD2 1 ATOM 434 N N . ALA A 1 61 ? -12.771 -24.932 75.718 1.00 66.08 ? 62 ALA A N 1 ATOM 435 C CA . ALA A 1 61 ? -13.766 -24.149 75.011 1.00 56.74 ? 62 ALA A CA 1 ATOM 436 C C . ALA A 1 61 ? -13.080 -23.066 74.206 1.00 57.72 ? 62 ALA A C 1 ATOM 437 O O . ALA A 1 61 ? -13.509 -21.914 74.203 1.00 56.90 ? 62 ALA A O 1 ATOM 438 C CB . ALA A 1 61 ? -14.757 -23.532 75.992 1.00 52.65 ? 62 ALA A CB 1 ATOM 439 N N . THR A 1 62 ? -12.002 -23.430 73.527 1.00 59.94 ? 63 THR A N 1 ATOM 440 C CA . THR A 1 62 ? -11.261 -22.452 72.739 1.00 62.90 ? 63 THR A CA 1 ATOM 441 C C . THR A 1 62 ? -11.683 -22.495 71.281 1.00 69.66 ? 63 THR A C 1 ATOM 442 O O . THR A 1 62 ? -11.487 -21.533 70.535 1.00 69.89 ? 63 THR A O 1 ATOM 443 C CB . THR A 1 62 ? -9.748 -22.706 72.810 1.00 71.29 ? 63 THR A CB 1 ATOM 444 O OG1 . THR A 1 62 ? -9.473 -24.062 72.428 1.00 74.92 ? 63 THR A OG1 1 ATOM 445 C CG2 . THR A 1 62 ? -9.232 -22.469 74.224 1.00 68.33 ? 63 THR A CG2 1 ATOM 446 N N . THR A 1 63 ? -12.262 -23.620 70.873 1.00 66.82 ? 64 THR A N 1 ATOM 447 C CA . THR A 1 63 ? -12.605 -23.804 69.478 1.00 67.21 ? 64 THR A CA 1 ATOM 448 C C . THR A 1 63 ? -14.010 -24.371 69.266 1.00 68.42 ? 64 THR A C 1 ATOM 449 O O . THR A 1 63 ? -14.559 -25.062 70.135 1.00 62.98 ? 64 THR A O 1 ATOM 450 C CB . THR A 1 63 ? -11.574 -24.695 68.770 1.00 66.44 ? 64 THR A CB 1 ATOM 451 O OG1 . THR A 1 63 ? -11.975 -24.882 67.402 1.00 83.15 ? 64 THR A OG1 1 ATOM 452 C CG2 . THR A 1 63 ? -11.467 -26.039 69.468 1.00 54.95 ? 64 THR A CG2 1 ATOM 453 N N . PHE A 1 64 ? -14.573 -24.061 68.097 1.00 63.16 ? 65 PHE A N 1 ATOM 454 C CA . PHE A 1 64 ? -15.889 -24.549 67.690 1.00 62.80 ? 65 PHE A CA 1 ATOM 455 C C . PHE A 1 64 ? -15.916 -26.062 67.589 1.00 63.53 ? 65 PHE A C 1 ATOM 456 O O . PHE A 1 64 ? -14.916 -26.691 67.244 1.00 62.55 ? 65 PHE A O 1 ATOM 457 C CB . PHE A 1 64 ? -16.310 -23.961 66.339 1.00 53.09 ? 65 PHE A CB 1 ATOM 458 C CG . PHE A 1 64 ? -16.761 -22.532 66.412 1.00 51.27 ? 65 PHE A CG 1 ATOM 459 C CD1 . PHE A 1 64 ? -17.927 -22.192 67.082 1.00 54.59 ? 65 PHE A CD1 1 ATOM 460 C CD2 . PHE A 1 64 ? -16.029 -21.528 65.804 1.00 52.11 ? 65 PHE A CD2 1 ATOM 461 C CE1 . PHE A 1 64 ? -18.357 -20.872 67.152 1.00 49.51 ? 65 PHE A CE1 1 ATOM 462 C CE2 . PHE A 1 64 ? -16.448 -20.208 65.868 1.00 54.75 ? 65 PHE A CE2 1 ATOM 463 C CZ . PHE A 1 64 ? -17.619 -19.882 66.541 1.00 54.56 ? 65 PHE A CZ 1 ATOM 464 N N . GLN A 1 65 ? -17.079 -26.637 67.886 1.00 65.46 ? 66 GLN A N 1 ATOM 465 C CA . GLN A 1 65 ? -17.285 -28.067 67.742 1.00 55.56 ? 66 GLN A CA 1 ATOM 466 C C . GLN A 1 65 ? -17.877 -28.469 66.383 1.00 63.26 ? 66 GLN A C 1 ATOM 467 O O . GLN A 1 65 ? -18.187 -27.624 65.530 1.00 59.35 ? 66 GLN A O 1 ATOM 468 C CB . GLN A 1 65 ? -18.152 -28.594 68.871 1.00 58.11 ? 66 GLN A CB 1 ATOM 469 C CG . GLN A 1 65 ? -17.374 -29.016 70.108 1.00 61.06 ? 66 GLN A CG 1 ATOM 470 C CD . GLN A 1 65 ? -16.692 -30.359 69.928 1.00 67.51 ? 66 GLN A CD 1 ATOM 471 O OE1 . GLN A 1 65 ? -16.827 -31.012 68.882 1.00 64.10 ? 66 GLN A OE1 1 ATOM 472 N NE2 . GLN A 1 65 ? -15.954 -30.785 70.948 1.00 61.20 ? 66 GLN A NE2 1 ATOM 473 N N . SER A 1 66 ? -18.007 -29.779 66.209 1.00 54.51 ? 67 SER A N 1 ATOM 474 C CA . SER A 1 66 ? -18.552 -30.383 65.016 1.00 55.31 ? 67 SER A CA 1 ATOM 475 C C . SER A 1 66 ? -19.888 -29.783 64.567 1.00 60.97 ? 67 SER A C 1 ATOM 476 O O . SER A 1 66 ? -20.724 -29.379 65.382 1.00 55.69 ? 67 SER A O 1 ATOM 477 C CB . SER A 1 66 ? -18.704 -31.883 65.243 1.00 59.94 ? 67 SER A CB 1 ATOM 478 O OG . SER A 1 66 ? -17.440 -32.488 65.446 1.00 62.34 ? 67 SER A OG 1 ATOM 479 N N . VAL A 1 67 ? -20.065 -29.718 63.253 1.00 58.87 ? 68 VAL A N 1 ATOM 480 C CA . VAL A 1 67 ? -21.337 -29.336 62.658 1.00 55.15 ? 68 VAL A CA 1 ATOM 481 C C . VAL A 1 67 ? -22.288 -30.542 62.703 1.00 52.91 ? 68 VAL A C 1 ATOM 482 O O . VAL A 1 67 ? -21.850 -31.703 62.602 1.00 47.94 ? 68 VAL A O 1 ATOM 483 C CB . VAL A 1 67 ? -21.123 -28.803 61.210 1.00 55.53 ? 68 VAL A CB 1 ATOM 484 C CG1 . VAL A 1 67 ? -22.426 -28.729 60.437 1.00 52.93 ? 68 VAL A CG1 1 ATOM 485 C CG2 . VAL A 1 67 ? -20.473 -27.437 61.254 1.00 52.11 ? 68 VAL A CG2 1 ATOM 486 N N . CYS A 1 68 ? -23.576 -30.273 62.908 1.00 51.21 ? 69 CYS A N 1 ATOM 487 C CA . CYS A 1 68 ? -24.589 -31.330 62.901 1.00 49.82 ? 69 CYS A CA 1 ATOM 488 C C . CYS A 1 68 ? -24.681 -31.965 61.520 1.00 54.64 ? 69 CYS A C 1 ATOM 489 O O . CYS A 1 68 ? -24.744 -31.250 60.513 1.00 51.84 ? 69 CYS A O 1 ATOM 490 C CB . CYS A 1 68 ? -25.945 -30.767 63.323 1.00 45.46 ? 69 CYS A CB 1 ATOM 491 S SG . CYS A 1 68 ? -26.103 -30.505 65.129 1.00 62.95 ? 69 CYS A SG 1 ATOM 492 N N . TYR A 1 69 ? -24.691 -33.298 61.476 1.00 53.24 ? 70 TYR A N 1 ATOM 493 C CA . TYR A 1 69 ? -24.702 -34.043 60.200 1.00 58.23 ? 70 TYR A CA 1 ATOM 494 C C . TYR A 1 69 ? -25.752 -33.552 59.190 1.00 55.89 ? 70 TYR A C 1 ATOM 495 O O . TYR A 1 69 ? -26.955 -33.579 59.452 1.00 60.09 ? 70 TYR A O 1 ATOM 496 C CB . TYR A 1 69 ? -24.874 -35.548 60.438 1.00 54.34 ? 70 TYR A CB 1 ATOM 497 C CG . TYR A 1 69 ? -24.010 -36.410 59.543 1.00 59.58 ? 70 TYR A CG 1 ATOM 498 C CD1 . TYR A 1 69 ? -22.761 -36.860 59.971 1.00 58.09 ? 70 TYR A CD1 1 ATOM 499 C CD2 . TYR A 1 69 ? -24.432 -36.768 58.265 1.00 59.13 ? 70 TYR A CD2 1 ATOM 500 C CE1 . TYR A 1 69 ? -21.961 -37.650 59.153 1.00 61.90 ? 70 TYR A CE1 1 ATOM 501 C CE2 . TYR A 1 69 ? -23.640 -37.557 57.440 1.00 61.98 ? 70 TYR A CE2 1 ATOM 502 C CZ . TYR A 1 69 ? -22.408 -37.998 57.885 1.00 67.08 ? 70 TYR A CZ 1 ATOM 503 O OH . TYR A 1 69 ? -21.622 -38.782 57.059 1.00 78.43 ? 70 TYR A OH 1 ATOM 504 N N . GLN A 1 70 ? -25.289 -33.100 58.031 1.00 56.89 ? 71 GLN A N 1 ATOM 505 C CA . GLN A 1 70 ? -26.196 -32.475 57.085 1.00 55.61 ? 71 GLN A CA 1 ATOM 506 C C . GLN A 1 70 ? -25.782 -32.668 55.635 1.00 57.88 ? 71 GLN A C 1 ATOM 507 O O . GLN A 1 70 ? -24.662 -33.086 55.342 1.00 60.82 ? 71 GLN A O 1 ATOM 508 C CB . GLN A 1 70 ? -26.354 -30.981 57.411 1.00 51.88 ? 71 GLN A CB 1 ATOM 509 C CG . GLN A 1 70 ? -25.100 -30.128 57.278 1.00 44.20 ? 71 GLN A CG 1 ATOM 510 C CD . GLN A 1 70 ? -25.277 -28.776 57.961 1.00 54.00 ? 71 GLN A CD 1 ATOM 511 O OE1 . GLN A 1 70 ? -25.341 -27.734 57.308 1.00 56.09 ? 71 GLN A OE1 1 ATOM 512 N NE2 . GLN A 1 70 ? -25.356 -28.793 59.294 1.00 52.73 ? 71 GLN A NE2 1 ATOM 513 N N . TYR A 1 71 ? -26.710 -32.371 54.734 1.00 59.89 ? 72 TYR A N 1 ATOM 514 C CA . TYR A 1 71 ? -26.410 -32.278 53.316 1.00 56.01 ? 72 TYR A CA 1 ATOM 515 C C . TYR A 1 71 ? -25.529 -31.050 53.081 1.00 61.53 ? 72 TYR A C 1 ATOM 516 O O . TYR A 1 71 ? -25.658 -30.045 53.793 1.00 55.79 ? 72 TYR A O 1 ATOM 517 C CB . TYR A 1 71 ? -27.716 -32.183 52.530 1.00 56.47 ? 72 TYR A CB 1 ATOM 518 C CG . TYR A 1 71 ? -27.566 -31.696 51.105 1.00 65.13 ? 72 TYR A CG 1 ATOM 519 C CD1 . TYR A 1 71 ? -27.061 -32.529 50.111 1.00 59.80 ? 72 TYR A CD1 1 ATOM 520 C CD2 . TYR A 1 71 ? -27.947 -30.404 50.751 1.00 57.91 ? 72 TYR A CD2 1 ATOM 521 C CE1 . TYR A 1 71 ? -26.926 -32.082 48.808 1.00 64.90 ? 72 TYR A CE1 1 ATOM 522 C CE2 . TYR A 1 71 ? -27.818 -29.954 49.451 1.00 61.12 ? 72 TYR A CE2 1 ATOM 523 C CZ . TYR A 1 71 ? -27.306 -30.794 48.483 1.00 62.35 ? 72 TYR A CZ 1 ATOM 524 O OH . TYR A 1 71 ? -27.175 -30.347 47.189 1.00 59.41 ? 72 TYR A OH 1 ATOM 525 N N . VAL A 1 72 ? -24.626 -31.136 52.101 1.00 58.89 ? 73 VAL A N 1 ATOM 526 C CA . VAL A 1 72 ? -23.772 -30.004 51.744 1.00 54.33 ? 73 VAL A CA 1 ATOM 527 C C . VAL A 1 72 ? -24.151 -29.435 50.368 1.00 61.75 ? 73 VAL A C 1 ATOM 528 O O . VAL A 1 72 ? -24.005 -30.112 49.343 1.00 62.97 ? 73 VAL A O 1 ATOM 529 C CB . VAL A 1 72 ? -22.299 -30.412 51.748 1.00 54.39 ? 73 VAL A CB 1 ATOM 530 C CG1 . VAL A 1 72 ? -21.423 -29.213 51.433 1.00 53.53 ? 73 VAL A CG1 1 ATOM 531 C CG2 . VAL A 1 72 ? -21.931 -31.014 53.099 1.00 60.17 ? 73 VAL A CG2 1 ATOM 532 N N . ASP A 1 73 ? -24.647 -28.200 50.339 1.00 57.69 ? 74 ASP A N 1 ATOM 533 C CA . ASP A 1 73 ? -25.099 -27.611 49.076 1.00 57.72 ? 74 ASP A CA 1 ATOM 534 C C . ASP A 1 73 ? -23.934 -27.334 48.131 1.00 62.78 ? 74 ASP A C 1 ATOM 535 O O . ASP A 1 73 ? -23.099 -26.465 48.391 1.00 62.64 ? 74 ASP A O 1 ATOM 536 C CB . ASP A 1 73 ? -25.936 -26.346 49.299 1.00 55.15 ? 74 ASP A CB 1 ATOM 537 C CG . ASP A 1 73 ? -26.439 -25.731 47.993 1.00 63.89 ? 74 ASP A CG 1 ATOM 538 O OD1 . ASP A 1 73 ? -26.521 -26.453 46.970 1.00 73.58 ? 74 ASP A OD1 1 ATOM 539 O OD2 . ASP A 1 73 ? -26.762 -24.523 47.986 1.00 62.70 ? 74 ASP A OD2 1 ATOM 540 N N . THR A 1 74 ? -23.904 -28.088 47.032 1.00 58.96 ? 75 THR A N 1 ATOM 541 C CA . THR A 1 74 ? -22.827 -28.030 46.055 1.00 50.99 ? 75 THR A CA 1 ATOM 542 C C . THR A 1 74 ? -23.340 -27.696 44.660 1.00 61.04 ? 75 THR A C 1 ATOM 543 O O . THR A 1 74 ? -22.803 -28.180 43.665 1.00 60.94 ? 75 THR A O 1 ATOM 544 C CB . THR A 1 74 ? -22.087 -29.372 45.947 1.00 52.88 ? 75 THR A CB 1 ATOM 545 O OG1 . THR A 1 74 ? -23.035 -30.420 45.709 1.00 56.05 ? 75 THR A OG1 1 ATOM 546 C CG2 . THR A 1 74 ? -21.288 -29.665 47.215 1.00 62.26 ? 75 THR A CG2 1 ATOM 547 N N . LEU A 1 75 ? -24.379 -26.876 44.590 1.00 62.30 ? 76 LEU A N 1 ATOM 548 C CA . LEU A 1 75 ? -24.846 -26.346 43.314 1.00 61.12 ? 76 LEU A CA 1 ATOM 549 C C . LEU A 1 75 ? -23.694 -25.773 42.477 1.00 57.35 ? 76 LEU A C 1 ATOM 550 O O . LEU A 1 75 ? -23.490 -26.162 41.331 1.00 62.98 ? 76 LEU A O 1 ATOM 551 C CB . LEU A 1 75 ? -25.894 -25.256 43.564 1.00 58.00 ? 76 LEU A CB 1 ATOM 552 C CG . LEU A 1 75 ? -26.616 -24.726 42.328 1.00 63.58 ? 76 LEU A CG 1 ATOM 553 C CD1 . LEU A 1 75 ? -27.161 -25.903 41.516 1.00 46.18 ? 76 LEU A CD1 1 ATOM 554 C CD2 . LEU A 1 75 ? -27.729 -23.758 42.740 1.00 55.65 ? 76 LEU A CD2 1 ATOM 555 N N . TYR A 1 76 ? -22.936 -24.872 43.091 1.00 60.56 ? 77 TYR A N 1 ATOM 556 C CA . TYR A 1 76 ? -21.933 -24.057 42.429 1.00 56.34 ? 77 TYR A CA 1 ATOM 557 C C . TYR A 1 76 ? -20.563 -24.219 43.081 1.00 62.67 ? 77 TYR A C 1 ATOM 558 O O . TYR A 1 76 ? -20.151 -23.352 43.850 1.00 64.09 ? 77 TYR A O 1 ATOM 559 C CB . TYR A 1 76 ? -22.347 -22.597 42.569 1.00 50.36 ? 77 TYR A CB 1 ATOM 560 C CG . TYR A 1 76 ? -23.563 -22.227 41.773 1.00 60.68 ? 77 TYR A CG 1 ATOM 561 C CD1 . TYR A 1 76 ? -23.663 -22.583 40.431 1.00 60.40 ? 77 TYR A CD1 1 ATOM 562 C CD2 . TYR A 1 76 ? -24.617 -21.523 42.344 1.00 59.87 ? 77 TYR A CD2 1 ATOM 563 C CE1 . TYR A 1 76 ? -24.767 -22.251 39.680 1.00 54.23 ? 77 TYR A CE1 1 ATOM 564 C CE2 . TYR A 1 76 ? -25.743 -21.173 41.585 1.00 63.59 ? 77 TYR A CE2 1 ATOM 565 C CZ . TYR A 1 76 ? -25.806 -21.547 40.244 1.00 61.81 ? 77 TYR A CZ 1 ATOM 566 O OH . TYR A 1 76 ? -26.896 -21.233 39.447 1.00 63.42 ? 77 TYR A OH 1 ATOM 567 N N . PRO A 1 77 ? -19.851 -25.317 42.776 1.00 61.80 ? 78 PRO A N 1 ATOM 568 C CA . PRO A 1 77 ? -18.519 -25.601 43.331 1.00 64.31 ? 78 PRO A CA 1 ATOM 569 C C . PRO A 1 77 ? -17.576 -24.408 43.261 1.00 69.94 ? 78 PRO A C 1 ATOM 570 O O . PRO A 1 77 ? -17.441 -23.795 42.203 1.00 64.17 ? 78 PRO A O 1 ATOM 571 C CB . PRO A 1 77 ? -17.992 -26.710 42.425 1.00 59.22 ? 78 PRO A CB 1 ATOM 572 C CG . PRO A 1 77 ? -19.195 -27.397 41.949 1.00 63.87 ? 78 PRO A CG 1 ATOM 573 C CD . PRO A 1 77 ? -20.275 -26.356 41.826 1.00 66.50 ? 78 PRO A CD 1 ATOM 574 N N . GLY A 1 78 ? -16.958 -24.073 44.392 1.00 72.47 ? 79 GLY A N 1 ATOM 575 C CA . GLY A 1 78 ? -16.023 -22.964 44.457 1.00 67.56 ? 79 GLY A CA 1 ATOM 576 C C . GLY A 1 78 ? -16.639 -21.577 44.565 1.00 72.66 ? 79 GLY A C 1 ATOM 577 O O . GLY A 1 78 ? -15.915 -20.583 44.650 1.00 76.06 ? 79 GLY A O 1 ATOM 578 N N . PHE A 1 79 ? -17.967 -21.497 44.564 1.00 68.77 ? 80 PHE A N 1 ATOM 579 C CA . PHE A 1 79 ? -18.655 -20.211 44.647 1.00 59.84 ? 80 PHE A CA 1 ATOM 580 C C . PHE A 1 79 ? -18.928 -19.812 46.116 1.00 68.90 ? 80 PHE A C 1 ATOM 581 O O . PHE A 1 79 ? -19.480 -20.599 46.897 1.00 66.71 ? 80 PHE A O 1 ATOM 582 C CB . PHE A 1 79 ? -19.948 -20.273 43.833 1.00 51.68 ? 80 PHE A CB 1 ATOM 583 C CG . PHE A 1 79 ? -20.739 -18.991 43.832 1.00 63.04 ? 80 PHE A CG 1 ATOM 584 C CD1 . PHE A 1 79 ? -20.148 -17.788 43.477 1.00 60.42 ? 80 PHE A CD1 1 ATOM 585 C CD2 . PHE A 1 79 ? -22.085 -18.992 44.163 1.00 62.36 ? 80 PHE A CD2 1 ATOM 586 C CE1 . PHE A 1 79 ? -20.878 -16.603 43.478 1.00 53.53 ? 80 PHE A CE1 1 ATOM 587 C CE2 . PHE A 1 79 ? -22.821 -17.816 44.152 1.00 63.15 ? 80 PHE A CE2 1 ATOM 588 C CZ . PHE A 1 79 ? -22.211 -16.618 43.808 1.00 59.16 ? 80 PHE A CZ 1 ATOM 589 N N . GLU A 1 80 ? -18.544 -18.591 46.487 1.00 65.21 ? 81 GLU A N 1 ATOM 590 C CA . GLU A 1 80 ? -18.675 -18.130 47.871 1.00 69.55 ? 81 GLU A CA 1 ATOM 591 C C . GLU A 1 80 ? -20.138 -17.962 48.310 1.00 70.45 ? 81 GLU A C 1 ATOM 592 O O . GLU A 1 80 ? -20.487 -18.276 49.458 1.00 62.64 ? 81 GLU A O 1 ATOM 593 C CB . GLU A 1 80 ? -17.908 -16.819 48.090 1.00 71.02 ? 81 GLU A CB 1 ATOM 594 C CG . GLU A 1 80 ? -17.785 -16.410 49.557 1.00 81.24 ? 81 GLU A CG 1 ATOM 595 C CD . GLU A 1 80 ? -17.909 -14.906 49.783 1.00 84.28 ? 81 GLU A CD 1 ATOM 596 O OE1 . GLU A 1 80 ? -18.683 -14.241 49.056 1.00 81.61 ? 81 GLU A OE1 1 ATOM 597 O OE2 . GLU A 1 80 ? -17.235 -14.390 50.701 1.00 90.93 ? 81 GLU A OE2 1 ATOM 598 N N . GLY A 1 81 ? -20.978 -17.467 47.397 1.00 62.73 ? 82 GLY A N 1 ATOM 599 C CA . GLY A 1 81 ? -22.401 -17.299 47.651 1.00 63.18 ? 82 GLY A CA 1 ATOM 600 C C . GLY A 1 81 ? -23.122 -18.520 48.215 1.00 66.80 ? 82 GLY A C 1 ATOM 601 O O . GLY A 1 81 ? -24.042 -18.384 49.020 1.00 63.58 ? 82 GLY A O 1 ATOM 602 N N . THR A 1 82 ? -22.719 -19.715 47.792 1.00 66.53 ? 83 THR A N 1 ATOM 603 C CA . THR A 1 82 ? -23.276 -20.939 48.367 1.00 67.66 ? 83 THR A CA 1 ATOM 604 C C . THR A 1 82 ? -22.380 -21.569 49.448 1.00 66.11 ? 83 THR A C 1 ATOM 605 O O . THR A 1 82 ? -22.887 -22.139 50.415 1.00 65.38 ? 83 THR A O 1 ATOM 606 C CB . THR A 1 82 ? -23.614 -22.010 47.288 1.00 60.53 ? 83 THR A CB 1 ATOM 607 O OG1 . THR A 1 82 ? -22.433 -22.349 46.546 1.00 58.77 ? 83 THR A OG1 1 ATOM 608 C CG2 . THR A 1 82 ? -24.700 -21.504 46.355 1.00 50.09 ? 83 THR A CG2 1 ATOM 609 N N . GLU A 1 83 ? -21.061 -21.471 49.284 1.00 64.36 ? 84 GLU A N 1 ATOM 610 C CA . GLU A 1 83 ? -20.130 -22.160 50.179 1.00 64.20 ? 84 GLU A CA 1 ATOM 611 C C . GLU A 1 83 ? -20.032 -21.516 51.565 1.00 63.86 ? 84 GLU A C 1 ATOM 612 O O . GLU A 1 83 ? -19.691 -22.180 52.536 1.00 60.89 ? 84 GLU A O 1 ATOM 613 C CB . GLU A 1 83 ? -18.738 -22.291 49.548 1.00 64.30 ? 84 GLU A CB 1 ATOM 614 C CG . GLU A 1 83 ? -18.609 -23.433 48.540 1.00 67.83 ? 84 GLU A CG 1 ATOM 615 C CD . GLU A 1 83 ? -17.179 -23.615 48.031 1.00 81.67 ? 84 GLU A CD 1 ATOM 616 O OE1 . GLU A 1 83 ? -16.337 -22.720 48.282 1.00 79.26 ? 84 GLU A OE1 1 ATOM 617 O OE2 . GLU A 1 83 ? -16.897 -24.652 47.382 1.00 82.05 ? 84 GLU A OE2 1 ATOM 618 N N . MET A 1 84 ? -20.353 -20.230 51.650 1.00 61.16 ? 85 MET A N 1 ATOM 619 C CA . MET A 1 84 ? -20.306 -19.514 52.909 1.00 53.20 ? 85 MET A CA 1 ATOM 620 C C . MET A 1 84 ? -21.353 -20.049 53.897 1.00 60.33 ? 85 MET A C 1 ATOM 621 O O . MET A 1 84 ? -21.315 -19.729 55.095 1.00 59.65 ? 85 MET A O 1 ATOM 622 C CB . MET A 1 84 ? -20.498 -18.009 52.673 1.00 51.42 ? 85 MET A CB 1 ATOM 623 C CG . MET A 1 84 ? -21.922 -17.611 52.348 1.00 54.07 ? 85 MET A CG 1 ATOM 624 S SD . MET A 1 84 ? -22.141 -15.839 52.076 1.00 65.57 ? 85 MET A SD 1 ATOM 625 C CE . MET A 1 84 ? -22.553 -15.235 53.732 1.00 53.84 ? 85 MET A CE 1 ATOM 626 N N . TRP A 1 85 ? -22.279 -20.865 53.396 1.00 54.73 ? 86 TRP A N 1 ATOM 627 C CA . TRP A 1 85 ? -23.341 -21.425 54.231 1.00 58.30 ? 86 TRP A CA 1 ATOM 628 C C . TRP A 1 85 ? -23.071 -22.890 54.572 1.00 59.59 ? 86 TRP A C 1 ATOM 629 O O . TRP A 1 85 ? -23.748 -23.470 55.423 1.00 52.56 ? 86 TRP A O 1 ATOM 630 C CB . TRP A 1 85 ? -24.709 -21.288 53.552 1.00 50.31 ? 86 TRP A CB 1 ATOM 631 C CG . TRP A 1 85 ? -25.073 -19.892 53.208 1.00 51.31 ? 86 TRP A CG 1 ATOM 632 C CD1 . TRP A 1 85 ? -25.146 -19.353 51.961 1.00 57.07 ? 86 TRP A CD1 1 ATOM 633 C CD2 . TRP A 1 85 ? -25.390 -18.834 54.123 1.00 57.80 ? 86 TRP A CD2 1 ATOM 634 N NE1 . TRP A 1 85 ? -25.505 -18.031 52.036 1.00 59.96 ? 86 TRP A NE1 1 ATOM 635 C CE2 . TRP A 1 85 ? -25.664 -17.687 53.352 1.00 57.09 ? 86 TRP A CE2 1 ATOM 636 C CE3 . TRP A 1 85 ? -25.475 -18.746 55.519 1.00 52.94 ? 86 TRP A CE3 1 ATOM 637 C CZ2 . TRP A 1 85 ? -26.014 -16.464 53.928 1.00 57.04 ? 86 TRP A CZ2 1 ATOM 638 C CZ3 . TRP A 1 85 ? -25.824 -17.539 56.085 1.00 54.33 ? 86 TRP A CZ3 1 ATOM 639 C CH2 . TRP A 1 85 ? -26.085 -16.411 55.292 1.00 58.07 ? 86 TRP A CH2 1 ATOM 640 N N . ASN A 1 86 ? -22.076 -23.467 53.902 1.00 54.19 ? 87 ASN A N 1 ATOM 641 C CA . ASN A 1 86 ? -21.685 -24.858 54.091 1.00 50.75 ? 87 ASN A CA 1 ATOM 642 C C . ASN A 1 86 ? -20.963 -25.091 55.414 1.00 57.16 ? 87 ASN A C 1 ATOM 643 O O . ASN A 1 86 ? -20.405 -24.153 55.993 1.00 57.08 ? 87 ASN A O 1 ATOM 644 C CB . ASN A 1 86 ? -20.761 -25.299 52.937 1.00 64.71 ? 87 ASN A CB 1 ATOM 645 C CG . ASN A 1 86 ? -21.512 -25.545 51.624 1.00 64.52 ? 87 ASN A CG 1 ATOM 646 O OD1 . ASN A 1 86 ? -22.732 -25.743 51.600 1.00 64.18 ? 87 ASN A OD1 1 ATOM 647 N ND2 . ASN A 1 86 ? -20.775 -25.539 50.533 1.00 64.01 ? 87 ASN A ND2 1 ATOM 648 N N . PRO A 1 87 ? -20.950 -26.350 55.881 1.00 50.08 ? 88 PRO A N 1 ATOM 649 C CA . PRO A 1 87 ? -20.193 -26.729 57.073 1.00 54.74 ? 88 PRO A CA 1 ATOM 650 C C . PRO A 1 87 ? -18.728 -26.293 57.032 1.00 61.70 ? 88 PRO A C 1 ATOM 651 O O . PRO A 1 87 ? -18.024 -26.604 56.079 1.00 62.04 ? 88 PRO A O 1 ATOM 652 C CB . PRO A 1 87 ? -20.270 -28.261 57.054 1.00 48.28 ? 88 PRO A CB 1 ATOM 653 C CG . PRO A 1 87 ? -21.564 -28.545 56.408 1.00 55.65 ? 88 PRO A CG 1 ATOM 654 C CD . PRO A 1 87 ? -21.728 -27.485 55.346 1.00 51.09 ? 88 PRO A CD 1 ATOM 655 N N . ASN A 1 88 ? -18.268 -25.603 58.077 1.00 70.32 ? 89 ASN A N 1 ATOM 656 C CA . ASN A 1 88 ? -16.852 -25.244 58.182 1.00 65.19 ? 89 ASN A CA 1 ATOM 657 C C . ASN A 1 88 ? -16.100 -26.003 59.275 1.00 62.05 ? 89 ASN A C 1 ATOM 658 O O . ASN A 1 88 ? -15.058 -25.544 59.739 1.00 57.28 ? 89 ASN A O 1 ATOM 659 C CB . ASN A 1 88 ? -16.664 -23.732 58.353 1.00 61.38 ? 89 ASN A CB 1 ATOM 660 C CG . ASN A 1 88 ? -17.249 -23.210 59.643 1.00 66.37 ? 89 ASN A CG 1 ATOM 661 O OD1 . ASN A 1 88 ? -18.049 -23.884 60.296 1.00 67.32 ? 89 ASN A OD1 1 ATOM 662 N ND2 . ASN A 1 88 ? -16.868 -21.989 60.010 1.00 66.72 ? 89 ASN A ND2 1 ATOM 663 N N . ARG A 1 89 ? -16.640 -27.156 59.670 1.00 52.42 ? 90 ARG A N 1 ATOM 664 C CA . ARG A 1 89 ? -15.997 -28.066 60.619 1.00 57.52 ? 90 ARG A CA 1 ATOM 665 C C . ARG A 1 89 ? -16.505 -29.444 60.272 1.00 50.27 ? 90 ARG A C 1 ATOM 666 O O . ARG A 1 89 ? -17.553 -29.553 59.667 1.00 56.60 ? 90 ARG A O 1 ATOM 667 C CB . ARG A 1 89 ? -16.400 -27.748 62.065 1.00 54.02 ? 90 ARG A CB 1 ATOM 668 C CG . ARG A 1 89 ? -15.878 -26.436 62.619 1.00 58.96 ? 90 ARG A CG 1 ATOM 669 C CD . ARG A 1 89 ? -14.356 -26.448 62.732 1.00 57.66 ? 90 ARG A CD 1 ATOM 670 N NE . ARG A 1 89 ? -13.863 -25.293 63.476 1.00 68.28 ? 90 ARG A NE 1 ATOM 671 C CZ . ARG A 1 89 ? -13.776 -24.057 62.981 1.00 67.23 ? 90 ARG A CZ 1 ATOM 672 N NH1 . ARG A 1 89 ? -14.154 -23.803 61.736 1.00 56.81 ? 90 ARG A NH1 1 ATOM 673 N NH2 . ARG A 1 89 ? -13.319 -23.067 63.740 1.00 66.34 ? 90 ARG A NH2 1 ATOM 674 N N . GLU A 1 90 ? -15.793 -30.491 60.672 1.00 50.32 ? 91 GLU A N 1 ATOM 675 C CA . GLU A 1 90 ? -16.224 -31.855 60.364 1.00 55.79 ? 91 GLU A CA 1 ATOM 676 C C . GLU A 1 90 ? -17.645 -32.142 60.866 1.00 61.85 ? 91 GLU A C 1 ATOM 677 O O . GLU A 1 90 ? -18.057 -31.644 61.922 1.00 64.19 ? 91 GLU A O 1 ATOM 678 C CB . GLU A 1 90 ? -15.241 -32.905 60.904 1.00 48.52 ? 91 GLU A CB 1 ATOM 679 C CG . GLU A 1 90 ? -15.049 -32.842 62.403 1.00 77.67 ? 91 GLU A CG 1 ATOM 680 C CD . GLU A 1 90 ? -14.548 -34.154 62.985 1.00 99.44 ? 91 GLU A CD 1 ATOM 681 O OE1 . GLU A 1 90 ? -14.180 -35.052 62.186 1.00 101.18 ? 91 GLU A OE1 1 ATOM 682 O OE2 . GLU A 1 90 ? -14.533 -34.282 64.237 1.00 95.16 ? 91 GLU A OE2 1 ATOM 683 N N . LEU A 1 91 ? -18.393 -32.922 60.085 1.00 59.64 ? 92 LEU A N 1 ATOM 684 C CA . LEU A 1 91 ? -19.758 -33.298 60.438 1.00 57.41 ? 92 LEU A CA 1 ATOM 685 C C . LEU A 1 91 ? -19.755 -34.412 61.493 1.00 57.81 ? 92 LEU A C 1 ATOM 686 O O . LEU A 1 91 ? -18.904 -35.307 61.471 1.00 56.89 ? 92 LEU A O 1 ATOM 687 C CB . LEU A 1 91 ? -20.549 -33.753 59.200 1.00 52.96 ? 92 LEU A CB 1 ATOM 688 C CG . LEU A 1 91 ? -20.702 -32.819 57.982 1.00 58.06 ? 92 LEU A CG 1 ATOM 689 C CD1 . LEU A 1 91 ? -21.352 -33.541 56.791 1.00 49.59 ? 92 LEU A CD1 1 ATOM 690 C CD2 . LEU A 1 91 ? -21.516 -31.597 58.329 1.00 59.07 ? 92 LEU A CD2 1 ATOM 691 N N . SER A 1 92 ? -20.704 -34.352 62.422 1.00 50.60 ? 93 SER A N 1 ATOM 692 C CA . SER A 1 92 ? -20.848 -35.415 63.407 1.00 53.79 ? 93 SER A CA 1 ATOM 693 C C . SER A 1 92 ? -22.277 -35.444 63.914 1.00 51.79 ? 93 SER A C 1 ATOM 694 O O . SER A 1 92 ? -22.968 -34.437 63.886 1.00 57.35 ? 93 SER A O 1 ATOM 695 C CB . SER A 1 92 ? -19.863 -35.211 64.580 1.00 52.49 ? 93 SER A CB 1 ATOM 696 O OG . SER A 1 92 ? -19.903 -36.291 65.504 1.00 56.47 ? 93 SER A OG 1 ATOM 697 N N . GLU A 1 93 ? -22.722 -36.608 64.364 1.00 56.71 ? 94 GLU A N 1 ATOM 698 C CA . GLU A 1 93 ? -23.979 -36.687 65.082 1.00 57.23 ? 94 GLU A CA 1 ATOM 699 C C . GLU A 1 93 ? -23.781 -36.155 66.502 1.00 67.33 ? 94 GLU A C 1 ATOM 700 O O . GLU A 1 93 ? -24.707 -35.572 67.078 1.00 69.61 ? 94 GLU A O 1 ATOM 701 C CB . GLU A 1 93 ? -24.522 -38.108 65.084 1.00 59.78 ? 94 GLU A CB 1 ATOM 702 C CG . GLU A 1 93 ? -25.098 -38.536 63.745 1.00 57.78 ? 94 GLU A CG 1 ATOM 703 C CD . GLU A 1 93 ? -25.793 -39.877 63.823 1.00 67.97 ? 94 GLU A CD 1 ATOM 704 O OE1 . GLU A 1 93 ? -26.963 -39.920 64.265 1.00 71.13 ? 94 GLU A OE1 1 ATOM 705 O OE2 . GLU A 1 93 ? -25.160 -40.892 63.462 1.00 75.65 ? 94 GLU A OE2 1 ATOM 706 N N . ASP A 1 94 ? -22.571 -36.331 67.049 1.00 59.92 ? 95 ASP A N 1 ATOM 707 C CA . ASP A 1 94 ? -22.183 -35.656 68.291 1.00 54.53 ? 95 ASP A CA 1 ATOM 708 C C . ASP A 1 94 ? -21.905 -34.192 68.009 1.00 48.45 ? 95 ASP A C 1 ATOM 709 O O . ASP A 1 94 ? -20.766 -33.814 67.740 1.00 57.11 ? 95 ASP A O 1 ATOM 710 C CB . ASP A 1 94 ? -20.941 -36.309 68.906 1.00 65.39 ? 95 ASP A CB 1 ATOM 711 C CG . ASP A 1 94 ? -20.515 -35.664 70.233 1.00 67.94 ? 95 ASP A CG 1 ATOM 712 O OD1 . ASP A 1 94 ? -21.280 -34.848 70.812 1.00 64.14 ? 95 ASP A OD1 1 ATOM 713 O OD2 . ASP A 1 94 ? -19.399 -35.993 70.700 1.00 70.27 ? 95 ASP A OD2 1 ATOM 714 N N . CYS A 1 95 ? -22.950 -33.372 68.100 1.00 45.37 ? 96 CYS A N 1 ATOM 715 C CA . CYS A 1 95 ? -22.906 -31.984 67.640 1.00 51.41 ? 96 CYS A CA 1 ATOM 716 C C . CYS A 1 95 ? -23.624 -30.983 68.558 1.00 48.70 ? 96 CYS A C 1 ATOM 717 O O . CYS A 1 95 ? -23.677 -29.791 68.247 1.00 48.45 ? 96 CYS A O 1 ATOM 718 C CB . CYS A 1 95 ? -23.528 -31.891 66.231 1.00 59.06 ? 96 CYS A CB 1 ATOM 719 S SG . CYS A 1 95 ? -25.367 -32.128 66.171 1.00 62.07 ? 96 CYS A SG 1 ATOM 720 N N . LEU A 1 96 ? -24.183 -31.455 69.672 1.00 51.22 ? 97 LEU A N 1 ATOM 721 C CA . LEU A 1 96 ? -24.921 -30.560 70.566 1.00 50.98 ? 97 LEU A CA 1 ATOM 722 C C . LEU A 1 96 ? -24.005 -29.765 71.527 1.00 48.38 ? 97 LEU A C 1 ATOM 723 O O . LEU A 1 96 ? -23.740 -30.171 72.655 1.00 56.69 ? 97 LEU A O 1 ATOM 724 C CB . LEU A 1 96 ? -26.057 -31.302 71.291 1.00 46.22 ? 97 LEU A CB 1 ATOM 725 C CG . LEU A 1 96 ? -27.104 -31.976 70.383 1.00 49.62 ? 97 LEU A CG 1 ATOM 726 C CD1 . LEU A 1 96 ? -28.252 -32.587 71.164 1.00 45.24 ? 97 LEU A CD1 1 ATOM 727 C CD2 . LEU A 1 96 ? -27.647 -31.008 69.320 1.00 51.68 ? 97 LEU A CD2 1 ATOM 728 N N . TYR A 1 97 ? -23.535 -28.627 71.037 1.00 44.70 ? 98 TYR A N 1 ATOM 729 C CA . TYR A 1 97 ? -22.632 -27.743 71.733 1.00 45.09 ? 98 TYR A CA 1 ATOM 730 C C . TYR A 1 97 ? -23.141 -26.337 71.520 1.00 42.66 ? 98 TYR A C 1 ATOM 731 O O . TYR A 1 97 ? -23.818 -26.071 70.551 1.00 51.19 ? 98 TYR A O 1 ATOM 732 C CB . TYR A 1 97 ? -21.209 -27.881 71.187 1.00 43.40 ? 98 TYR A CB 1 ATOM 733 C CG . TYR A 1 97 ? -20.626 -29.260 71.380 1.00 48.25 ? 98 TYR A CG 1 ATOM 734 C CD1 . TYR A 1 97 ? -19.933 -29.593 72.541 1.00 55.35 ? 98 TYR A CD1 1 ATOM 735 C CD2 . TYR A 1 97 ? -20.792 -30.242 70.422 1.00 50.59 ? 98 TYR A CD2 1 ATOM 736 C CE1 . TYR A 1 97 ? -19.409 -30.867 72.731 1.00 52.69 ? 98 TYR A CE1 1 ATOM 737 C CE2 . TYR A 1 97 ? -20.268 -31.520 70.594 1.00 51.57 ? 98 TYR A CE2 1 ATOM 738 C CZ . TYR A 1 97 ? -19.575 -31.827 71.742 1.00 58.56 ? 98 TYR A CZ 1 ATOM 739 O OH . TYR A 1 97 ? -19.070 -33.101 71.902 1.00 59.54 ? 98 TYR A OH 1 ATOM 740 N N . LEU A 1 98 ? -22.836 -25.438 72.446 1.00 51.95 ? 99 LEU A N 1 ATOM 741 C CA . LEU A 1 98 ? -23.233 -24.040 72.324 1.00 45.65 ? 99 LEU A CA 1 ATOM 742 C C . LEU A 1 98 ? -22.057 -23.093 72.595 1.00 51.04 ? 99 LEU A C 1 ATOM 743 O O . LEU A 1 98 ? -20.999 -23.516 73.059 1.00 48.34 ? 99 LEU A O 1 ATOM 744 C CB . LEU A 1 98 ? -24.439 -23.725 73.211 1.00 46.78 ? 99 LEU A CB 1 ATOM 745 C CG . LEU A 1 98 ? -24.459 -24.068 74.709 1.00 49.66 ? 99 LEU A CG 1 ATOM 746 C CD1 . LEU A 1 98 ? -23.573 -23.123 75.551 1.00 45.01 ? 99 LEU A CD1 1 ATOM 747 C CD2 . LEU A 1 98 ? -25.889 -24.026 75.216 1.00 44.60 ? 99 LEU A CD2 1 ATOM 748 N N . ASN A 1 99 ? -22.242 -21.815 72.280 1.00 51.13 ? 100 ASN A N 1 ATOM 749 C CA . ASN A 1 99 ? -21.157 -20.849 72.356 1.00 51.81 ? 100 ASN A CA 1 ATOM 750 C C . ASN A 1 99 ? -21.579 -19.595 73.097 1.00 55.02 ? 100 ASN A C 1 ATOM 751 O O . ASN A 1 99 ? -22.703 -19.114 72.919 1.00 54.86 ? 100 ASN A O 1 ATOM 752 C CB . ASN A 1 99 ? -20.657 -20.476 70.947 1.00 52.39 ? 100 ASN A CB 1 ATOM 753 C CG . ASN A 1 99 ? -20.656 -21.662 69.986 1.00 53.64 ? 100 ASN A CG 1 ATOM 754 O OD1 . ASN A 1 99 ? -19.839 -22.580 70.097 1.00 49.56 ? 100 ASN A OD1 1 ATOM 755 N ND2 . ASN A 1 99 ? -21.573 -21.634 69.024 1.00 53.69 ? 100 ASN A ND2 1 ATOM 756 N N . VAL A 1 100 ? -20.681 -19.072 73.932 1.00 54.84 ? 101 VAL A N 1 ATOM 757 C CA . VAL A 1 100 ? -20.950 -17.847 74.689 1.00 52.88 ? 101 VAL A CA 1 ATOM 758 C C . VAL A 1 100 ? -19.885 -16.787 74.417 1.00 56.26 ? 101 VAL A C 1 ATOM 759 O O . VAL A 1 100 ? -18.685 -17.072 74.471 1.00 59.30 ? 101 VAL A O 1 ATOM 760 C CB . VAL A 1 100 ? -21.024 -18.109 76.218 1.00 53.85 ? 101 VAL A CB 1 ATOM 761 C CG1 . VAL A 1 100 ? -21.458 -16.838 76.959 1.00 53.60 ? 101 VAL A CG1 1 ATOM 762 C CG2 . VAL A 1 100 ? -21.976 -19.257 76.533 1.00 46.84 ? 101 VAL A CG2 1 ATOM 763 N N . TRP A 1 101 ? -20.329 -15.574 74.106 1.00 49.97 ? 102 TRP A N 1 ATOM 764 C CA . TRP A 1 101 ? -19.432 -14.435 73.943 1.00 56.60 ? 102 TRP A CA 1 ATOM 765 C C . TRP A 1 101 ? -19.791 -13.430 75.024 1.00 63.30 ? 102 TRP A C 1 ATOM 766 O O . TRP A 1 101 ? -20.968 -13.124 75.218 1.00 63.64 ? 102 TRP A O 1 ATOM 767 C CB . TRP A 1 101 ? -19.603 -13.754 72.581 1.00 55.06 ? 102 TRP A CB 1 ATOM 768 C CG . TRP A 1 101 ? -19.004 -14.470 71.420 1.00 62.40 ? 102 TRP A CG 1 ATOM 769 C CD1 . TRP A 1 101 ? -17.754 -14.293 70.904 1.00 64.61 ? 102 TRP A CD1 1 ATOM 770 C CD2 . TRP A 1 101 ? -19.636 -15.465 70.611 1.00 59.24 ? 102 TRP A CD2 1 ATOM 771 N NE1 . TRP A 1 101 ? -17.563 -15.125 69.832 1.00 61.81 ? 102 TRP A NE1 1 ATOM 772 C CE2 . TRP A 1 101 ? -18.704 -15.856 69.629 1.00 67.44 ? 102 TRP A CE2 1 ATOM 773 C CE3 . TRP A 1 101 ? -20.901 -16.070 70.624 1.00 60.10 ? 102 TRP A CE3 1 ATOM 774 C CZ2 . TRP A 1 101 ? -18.997 -16.822 68.658 1.00 67.05 ? 102 TRP A CZ2 1 ATOM 775 C CZ3 . TRP A 1 101 ? -21.191 -17.035 69.669 1.00 59.41 ? 102 TRP A CZ3 1 ATOM 776 C CH2 . TRP A 1 101 ? -20.240 -17.400 68.696 1.00 62.32 ? 102 TRP A CH2 1 ATOM 777 N N . THR A 1 102 ? -18.791 -12.898 75.716 1.00 57.19 ? 103 THR A N 1 ATOM 778 C CA . THR A 1 102 ? -19.069 -11.953 76.789 1.00 61.38 ? 103 THR A CA 1 ATOM 779 C C . THR A 1 102 ? -18.028 -10.835 76.824 1.00 62.58 ? 103 THR A C 1 ATOM 780 O O . THR A 1 102 ? -16.896 -11.028 76.375 1.00 62.23 ? 103 THR A O 1 ATOM 781 C CB . THR A 1 102 ? -19.159 -12.682 78.127 1.00 57.45 ? 103 THR A CB 1 ATOM 782 O OG1 . THR A 1 102 ? -19.898 -11.885 79.050 1.00 62.85 ? 103 THR A OG1 1 ATOM 783 C CG2 . THR A 1 102 ? -17.778 -12.999 78.671 1.00 54.43 ? 103 THR A CG2 1 ATOM 784 N N . PRO A 1 103 ? -18.415 -9.644 77.313 1.00 60.50 ? 104 PRO A N 1 ATOM 785 C CA . PRO A 1 103 ? -17.452 -8.530 77.261 1.00 63.33 ? 104 PRO A CA 1 ATOM 786 C C . PRO A 1 103 ? -16.179 -8.728 78.107 1.00 67.62 ? 104 PRO A C 1 ATOM 787 O O . PRO A 1 103 ? -16.120 -9.557 79.031 1.00 61.25 ? 104 PRO A O 1 ATOM 788 C CB . PRO A 1 103 ? -18.262 -7.336 77.779 1.00 62.35 ? 104 PRO A CB 1 ATOM 789 C CG . PRO A 1 103 ? -19.693 -7.705 77.532 1.00 64.82 ? 104 PRO A CG 1 ATOM 790 C CD . PRO A 1 103 ? -19.755 -9.198 77.732 1.00 55.64 ? 104 PRO A CD 1 ATOM 791 N N . TYR A 1 104 ? -15.149 -7.970 77.743 1.00 73.25 ? 105 TYR A N 1 ATOM 792 C CA . TYR A 1 104 ? -13.891 -7.931 78.478 1.00 73.88 ? 105 TYR A CA 1 ATOM 793 C C . TYR A 1 104 ? -13.647 -6.478 78.894 1.00 75.54 ? 105 TYR A C 1 ATOM 794 O O . TYR A 1 104 ? -13.480 -5.596 78.047 1.00 70.65 ? 105 TYR A O 1 ATOM 795 C CB . TYR A 1 104 ? -12.749 -8.474 77.619 1.00 75.59 ? 105 TYR A CB 1 ATOM 796 C CG . TYR A 1 104 ? -11.450 -8.759 78.348 1.00 88.11 ? 105 TYR A CG 1 ATOM 797 C CD1 . TYR A 1 104 ? -10.943 -7.873 79.294 1.00 88.91 ? 105 TYR A CD1 1 ATOM 798 C CD2 . TYR A 1 104 ? -10.720 -9.917 78.075 1.00 91.86 ? 105 TYR A CD2 1 ATOM 799 C CE1 . TYR A 1 104 ? -9.759 -8.129 79.955 1.00 100.34 ? 105 TYR A CE1 1 ATOM 800 C CE2 . TYR A 1 104 ? -9.528 -10.182 78.728 1.00 99.82 ? 105 TYR A CE2 1 ATOM 801 C CZ . TYR A 1 104 ? -9.053 -9.281 79.670 1.00 110.62 ? 105 TYR A CZ 1 ATOM 802 O OH . TYR A 1 104 ? -7.871 -9.521 80.334 1.00 114.15 ? 105 TYR A OH 1 ATOM 803 N N . PRO A 1 105 ? -13.642 -6.226 80.210 1.00 77.08 ? 106 PRO A N 1 ATOM 804 C CA . PRO A 1 105 ? -13.789 -7.265 81.235 1.00 79.42 ? 106 PRO A CA 1 ATOM 805 C C . PRO A 1 105 ? -15.254 -7.641 81.514 1.00 76.22 ? 106 PRO A C 1 ATOM 806 O O . PRO A 1 105 ? -16.163 -6.862 81.206 1.00 72.81 ? 106 PRO A O 1 ATOM 807 C CB . PRO A 1 105 ? -13.167 -6.604 82.465 1.00 77.82 ? 106 PRO A CB 1 ATOM 808 C CG . PRO A 1 105 ? -13.511 -5.157 82.293 1.00 75.04 ? 106 PRO A CG 1 ATOM 809 C CD . PRO A 1 105 ? -13.512 -4.883 80.806 1.00 72.52 ? 106 PRO A CD 1 ATOM 810 N N . ARG A 1 106 ? -15.456 -8.826 82.092 1.00 72.16 ? 107 ARG A N 1 ATOM 811 C CA . ARG A 1 106 ? -16.785 -9.363 82.397 1.00 75.04 ? 107 ARG A CA 1 ATOM 812 C C . ARG A 1 106 ? -17.640 -8.371 83.179 1.00 72.58 ? 107 ARG A C 1 ATOM 813 O O . ARG A 1 106 ? -17.198 -7.861 84.197 1.00 80.83 ? 107 ARG A O 1 ATOM 814 C CB . ARG A 1 106 ? -16.629 -10.655 83.188 1.00 70.74 ? 107 ARG A CB 1 ATOM 815 C CG . ARG A 1 106 ? -17.878 -11.491 83.277 1.00 75.24 ? 107 ARG A CG 1 ATOM 816 C CD . ARG A 1 106 ? -17.649 -12.674 84.210 1.00 77.57 ? 107 ARG A CD 1 ATOM 817 N NE . ARG A 1 106 ? -16.420 -13.393 83.881 1.00 83.70 ? 107 ARG A NE 1 ATOM 818 C CZ . ARG A 1 106 ? -15.943 -14.412 84.588 1.00 80.09 ? 107 ARG A CZ 1 ATOM 819 N NH1 . ARG A 1 106 ? -16.597 -14.829 85.661 1.00 82.50 ? 107 ARG A NH1 1 ATOM 820 N NH2 . ARG A 1 106 ? -14.819 -15.017 84.227 1.00 78.64 ? 107 ARG A NH2 1 ATOM 821 N N . PRO A 1 107 ? -18.867 -8.086 82.701 1.00 79.30 ? 108 PRO A N 1 ATOM 822 C CA . PRO A 1 107 ? -19.686 -7.044 83.339 1.00 81.65 ? 108 PRO A CA 1 ATOM 823 C C . PRO A 1 107 ? -19.982 -7.351 84.804 1.00 76.38 ? 108 PRO A C 1 ATOM 824 O O . PRO A 1 107 ? -19.993 -8.515 85.219 1.00 73.71 ? 108 PRO A O 1 ATOM 825 C CB . PRO A 1 107 ? -20.984 -7.050 82.507 1.00 82.10 ? 108 PRO A CB 1 ATOM 826 C CG . PRO A 1 107 ? -20.607 -7.655 81.205 1.00 68.25 ? 108 PRO A CG 1 ATOM 827 C CD . PRO A 1 107 ? -19.556 -8.684 81.543 1.00 73.79 ? 108 PRO A CD 1 ATOM 828 N N . THR A 1 108 ? -20.209 -6.305 85.588 1.00 81.41 ? 109 THR A N 1 ATOM 829 C CA . THR A 1 108 ? -20.438 -6.480 87.022 1.00 87.47 ? 109 THR A CA 1 ATOM 830 C C . THR A 1 108 ? -21.934 -6.529 87.326 1.00 84.94 ? 109 THR A C 1 ATOM 831 O O . THR A 1 108 ? -22.389 -7.325 88.152 1.00 84.71 ? 109 THR A O 1 ATOM 832 C CB . THR A 1 108 ? -19.765 -5.365 87.835 1.00 82.64 ? 109 THR A CB 1 ATOM 833 O OG1 . THR A 1 108 ? -20.336 -4.100 87.473 1.00 90.41 ? 109 THR A OG1 1 ATOM 834 C CG2 . THR A 1 108 ? -18.264 -5.346 87.556 1.00 64.42 ? 109 THR A CG2 1 ATOM 835 N N . SER A 1 109 ? -22.687 -5.667 86.650 1.00 79.18 ? 110 SER A N 1 ATOM 836 C CA . SER A 1 109 ? -24.140 -5.735 86.658 1.00 79.97 ? 110 SER A CA 1 ATOM 837 C C . SER A 1 109 ? -24.564 -6.764 85.608 1.00 81.78 ? 110 SER A C 1 ATOM 838 O O . SER A 1 109 ? -23.948 -6.844 84.545 1.00 81.99 ? 110 SER A O 1 ATOM 839 C CB . SER A 1 109 ? -24.719 -4.368 86.293 1.00 82.05 ? 110 SER A CB 1 ATOM 840 O OG . SER A 1 109 ? -23.860 -3.324 86.722 1.00 95.18 ? 110 SER A OG 1 ATOM 841 N N . PRO A 1 110 ? -25.617 -7.549 85.895 1.00 79.38 ? 111 PRO A N 1 ATOM 842 C CA . PRO A 1 110 ? -26.174 -8.547 84.962 1.00 72.66 ? 111 PRO A CA 1 ATOM 843 C C . PRO A 1 110 ? -26.587 -7.943 83.610 1.00 64.07 ? 111 PRO A C 1 ATOM 844 O O . PRO A 1 110 ? -27.533 -7.158 83.567 1.00 65.50 ? 111 PRO A O 1 ATOM 845 C CB . PRO A 1 110 ? -27.427 -9.054 85.691 1.00 64.61 ? 111 PRO A CB 1 ATOM 846 C CG . PRO A 1 110 ? -27.226 -8.697 87.102 1.00 63.22 ? 111 PRO A CG 1 ATOM 847 C CD . PRO A 1 110 ? -26.386 -7.469 87.147 1.00 64.75 ? 111 PRO A CD 1 ATOM 848 N N . THR A 1 111 ? -25.907 -8.303 82.522 1.00 60.73 ? 112 THR A N 1 ATOM 849 C CA . THR A 1 111 ? -26.226 -7.699 81.218 1.00 64.82 ? 112 THR A CA 1 ATOM 850 C C . THR A 1 111 ? -27.193 -8.535 80.335 1.00 61.11 ? 112 THR A C 1 ATOM 851 O O . THR A 1 111 ? -27.126 -9.765 80.318 1.00 62.35 ? 112 THR A O 1 ATOM 852 C CB . THR A 1 111 ? -24.943 -7.342 80.454 1.00 65.12 ? 112 THR A CB 1 ATOM 853 O OG1 . THR A 1 111 ? -25.274 -6.939 79.125 1.00 65.57 ? 112 THR A OG1 1 ATOM 854 C CG2 . THR A 1 111 ? -24.023 -8.526 80.373 1.00 68.87 ? 112 THR A CG2 1 ATOM 855 N N . PRO A 1 112 ? -28.120 -7.865 79.626 1.00 64.28 ? 113 PRO A N 1 ATOM 856 C CA . PRO A 1 112 ? -29.064 -8.522 78.698 1.00 65.13 ? 113 PRO A CA 1 ATOM 857 C C . PRO A 1 112 ? -28.423 -9.501 77.695 1.00 56.03 ? 113 PRO A C 1 ATOM 858 O O . PRO A 1 112 ? -27.358 -9.224 77.147 1.00 57.71 ? 113 PRO A O 1 ATOM 859 C CB . PRO A 1 112 ? -29.715 -7.347 77.957 1.00 64.29 ? 113 PRO A CB 1 ATOM 860 C CG . PRO A 1 112 ? -28.940 -6.113 78.378 1.00 61.87 ? 113 PRO A CG 1 ATOM 861 C CD . PRO A 1 112 ? -28.371 -6.420 79.714 1.00 61.89 ? 113 PRO A CD 1 ATOM 862 N N . VAL A 1 113 ? -29.082 -10.639 77.486 1.00 51.46 ? 114 VAL A N 1 ATOM 863 C CA . VAL A 1 113 ? -28.550 -11.729 76.672 1.00 53.84 ? 114 VAL A CA 1 ATOM 864 C C . VAL A 1 113 ? -29.239 -11.842 75.299 1.00 52.32 ? 114 VAL A C 1 ATOM 865 O O . VAL A 1 113 ? -30.462 -11.733 75.191 1.00 50.44 ? 114 VAL A O 1 ATOM 866 C CB . VAL A 1 113 ? -28.726 -13.072 77.403 1.00 56.05 ? 114 VAL A CB 1 ATOM 867 C CG1 . VAL A 1 113 ? -28.032 -14.181 76.639 1.00 53.45 ? 114 VAL A CG1 1 ATOM 868 C CG2 . VAL A 1 113 ? -28.182 -12.981 78.803 1.00 55.81 ? 114 VAL A CG2 1 ATOM 869 N N . LEU A 1 114 ? -28.443 -12.052 74.255 1.00 59.55 ? 115 LEU A N 1 ATOM 870 C CA . LEU A 1 114 ? -28.954 -12.293 72.899 1.00 52.86 ? 115 LEU A CA 1 ATOM 871 C C . LEU A 1 114 ? -28.679 -13.738 72.478 1.00 53.42 ? 115 LEU A C 1 ATOM 872 O O . LEU A 1 114 ? -27.519 -14.169 72.468 1.00 49.21 ? 115 LEU A O 1 ATOM 873 C CB . LEU A 1 114 ? -28.303 -11.340 71.897 1.00 50.86 ? 115 LEU A CB 1 ATOM 874 C CG . LEU A 1 114 ? -28.915 -9.943 71.744 1.00 64.55 ? 115 LEU A CG 1 ATOM 875 C CD1 . LEU A 1 114 ? -28.283 -9.172 70.591 1.00 54.69 ? 115 LEU A CD1 1 ATOM 876 C CD2 . LEU A 1 114 ? -30.410 -10.053 71.527 1.00 66.53 ? 115 LEU A CD2 1 ATOM 877 N N . VAL A 1 115 ? -29.733 -14.493 72.156 1.00 45.97 ? 116 VAL A N 1 ATOM 878 C CA . VAL A 1 115 ? -29.553 -15.883 71.704 1.00 50.21 ? 116 VAL A CA 1 ATOM 879 C C . VAL A 1 115 ? -29.826 -16.065 70.195 1.00 51.50 ? 116 VAL A C 1 ATOM 880 O O . VAL A 1 115 ? -30.900 -15.721 69.693 1.00 45.58 ? 116 VAL A O 1 ATOM 881 C CB . VAL A 1 115 ? -30.412 -16.870 72.520 1.00 49.29 ? 116 VAL A CB 1 ATOM 882 C CG1 . VAL A 1 115 ? -30.166 -18.290 72.055 1.00 45.45 ? 116 VAL A CG1 1 ATOM 883 C CG2 . VAL A 1 115 ? -30.100 -16.741 73.998 1.00 48.16 ? 116 VAL A CG2 1 ATOM 884 N N . TRP A 1 116 ? -28.841 -16.605 69.485 1.00 53.00 ? 117 TRP A N 1 ATOM 885 C CA . TRP A 1 116 ? -28.921 -16.771 68.039 1.00 49.73 ? 117 TRP A CA 1 ATOM 886 C C . TRP A 1 116 ? -29.339 -18.183 67.638 1.00 52.04 ? 117 TRP A C 1 ATOM 887 O O . TRP A 1 116 ? -28.709 -19.162 68.024 1.00 47.52 ? 117 TRP A O 1 ATOM 888 C CB . TRP A 1 116 ? -27.594 -16.388 67.365 1.00 45.95 ? 117 TRP A CB 1 ATOM 889 C CG . TRP A 1 116 ? -27.573 -16.631 65.869 1.00 56.02 ? 117 TRP A CG 1 ATOM 890 C CD1 . TRP A 1 116 ? -26.882 -17.613 65.201 1.00 53.44 ? 117 TRP A CD1 1 ATOM 891 C CD2 . TRP A 1 116 ? -28.279 -15.885 64.862 1.00 49.97 ? 117 TRP A CD2 1 ATOM 892 N NE1 . TRP A 1 116 ? -27.118 -17.519 63.843 1.00 57.66 ? 117 TRP A NE1 1 ATOM 893 C CE2 . TRP A 1 116 ? -27.972 -16.471 63.611 1.00 54.23 ? 117 TRP A CE2 1 ATOM 894 C CE3 . TRP A 1 116 ? -29.144 -14.789 64.897 1.00 50.89 ? 117 TRP A CE3 1 ATOM 895 C CZ2 . TRP A 1 116 ? -28.497 -15.989 62.406 1.00 53.98 ? 117 TRP A CZ2 1 ATOM 896 C CZ3 . TRP A 1 116 ? -29.662 -14.306 63.700 1.00 56.24 ? 117 TRP A CZ3 1 ATOM 897 C CH2 . TRP A 1 116 ? -29.339 -14.910 62.470 1.00 54.65 ? 117 TRP A CH2 1 ATOM 898 N N . ILE A 1 117 ? -30.420 -18.272 66.865 1.00 51.48 ? 118 ILE A N 1 ATOM 899 C CA . ILE A 1 117 ? -30.815 -19.528 66.232 1.00 49.61 ? 118 ILE A CA 1 ATOM 900 C C . ILE A 1 117 ? -30.656 -19.412 64.707 1.00 55.20 ? 118 ILE A C 1 ATOM 901 O O . ILE A 1 117 ? -31.386 -18.656 64.043 1.00 52.71 ? 118 ILE A O 1 ATOM 902 C CB . ILE A 1 117 ? -32.274 -19.892 66.565 1.00 45.40 ? 118 ILE A CB 1 ATOM 903 C CG1 . ILE A 1 117 ? -32.526 -19.786 68.069 1.00 49.28 ? 118 ILE A CG1 1 ATOM 904 C CG2 . ILE A 1 117 ? -32.610 -21.287 66.047 1.00 48.66 ? 118 ILE A CG2 1 ATOM 905 C CD1 . ILE A 1 117 ? -33.961 -20.021 68.457 1.00 44.21 ? 118 ILE A CD1 1 ATOM 906 N N . TYR A 1 118 ? -29.700 -20.148 64.149 1.00 55.26 ? 119 TYR A N 1 ATOM 907 C CA . TYR A 1 118 ? -29.445 -20.078 62.704 1.00 51.21 ? 119 TYR A CA 1 ATOM 908 C C . TYR A 1 118 ? -30.553 -20.695 61.853 1.00 53.92 ? 119 TYR A C 1 ATOM 909 O O . TYR A 1 118 ? -31.311 -21.561 62.318 1.00 48.53 ? 119 TYR A O 1 ATOM 910 C CB . TYR A 1 118 ? -28.108 -20.729 62.340 1.00 43.55 ? 119 TYR A CB 1 ATOM 911 C CG . TYR A 1 118 ? -27.965 -22.187 62.740 1.00 51.22 ? 119 TYR A CG 1 ATOM 912 C CD1 . TYR A 1 118 ? -28.597 -23.204 62.021 1.00 47.64 ? 119 TYR A CD1 1 ATOM 913 C CD2 . TYR A 1 118 ? -27.174 -22.549 63.836 1.00 54.10 ? 119 TYR A CD2 1 ATOM 914 C CE1 . TYR A 1 118 ? -28.454 -24.541 62.392 1.00 51.31 ? 119 TYR A CE1 1 ATOM 915 C CE2 . TYR A 1 118 ? -27.019 -23.878 64.214 1.00 47.23 ? 119 TYR A CE2 1 ATOM 916 C CZ . TYR A 1 118 ? -27.658 -24.868 63.498 1.00 50.87 ? 119 TYR A CZ 1 ATOM 917 O OH . TYR A 1 118 ? -27.490 -26.179 63.879 1.00 45.50 ? 119 TYR A OH 1 ATOM 918 N N . GLY A 1 119 ? -30.621 -20.251 60.598 1.00 56.92 ? 120 GLY A N 1 ATOM 919 C CA . GLY A 1 119 ? -31.488 -20.864 59.607 1.00 51.42 ? 120 GLY A CA 1 ATOM 920 C C . GLY A 1 119 ? -30.738 -21.786 58.663 1.00 45.82 ? 120 GLY A C 1 ATOM 921 O O . GLY A 1 119 ? -29.592 -22.165 58.928 1.00 49.71 ? 120 GLY A O 1 ATOM 922 N N . GLY A 1 120 ? -31.382 -22.122 57.546 1.00 54.13 ? 121 GLY A N 1 ATOM 923 C CA . GLY A 1 120 ? -30.870 -23.109 56.604 1.00 44.70 ? 121 GLY A CA 1 ATOM 924 C C . GLY A 1 120 ? -31.908 -24.176 56.301 1.00 44.22 ? 121 GLY A C 1 ATOM 925 O O . GLY A 1 120 ? -31.574 -25.354 56.141 1.00 44.65 ? 121 GLY A O 1 ATOM 926 N N . GLY A 1 121 ? -33.175 -23.767 56.262 1.00 46.43 ? 122 GLY A N 1 ATOM 927 C CA . GLY A 1 121 ? -34.270 -24.655 55.885 1.00 49.44 ? 122 GLY A CA 1 ATOM 928 C C . GLY A 1 121 ? -34.483 -25.924 56.705 1.00 51.30 ? 122 GLY A C 1 ATOM 929 O O . GLY A 1 121 ? -35.015 -26.916 56.197 1.00 54.26 ? 122 GLY A O 1 ATOM 930 N N . PHE A 1 122 ? -34.087 -25.896 57.979 1.00 53.98 ? 123 PHE A N 1 ATOM 931 C CA . PHE A 1 122 ? -34.145 -27.077 58.860 1.00 46.60 ? 123 PHE A CA 1 ATOM 932 C C . PHE A 1 122 ? -33.371 -28.291 58.334 1.00 49.64 ? 123 PHE A C 1 ATOM 933 O O . PHE A 1 122 ? -33.413 -29.349 58.959 1.00 47.42 ? 123 PHE A O 1 ATOM 934 C CB . PHE A 1 122 ? -35.584 -27.502 59.168 1.00 43.41 ? 123 PHE A CB 1 ATOM 935 C CG . PHE A 1 122 ? -36.396 -26.455 59.877 1.00 50.49 ? 123 PHE A CG 1 ATOM 936 C CD1 . PHE A 1 122 ? -36.194 -26.188 61.227 1.00 46.63 ? 123 PHE A CD1 1 ATOM 937 C CD2 . PHE A 1 122 ? -37.387 -25.759 59.205 1.00 46.70 ? 123 PHE A CD2 1 ATOM 938 C CE1 . PHE A 1 122 ? -36.950 -25.227 61.889 1.00 44.07 ? 123 PHE A CE1 1 ATOM 939 C CE2 . PHE A 1 122 ? -38.146 -24.807 59.857 1.00 46.43 ? 123 PHE A CE2 1 ATOM 940 C CZ . PHE A 1 122 ? -37.922 -24.535 61.210 1.00 48.86 ? 123 PHE A CZ 1 ATOM 941 N N . TYR A 1 123 ? -32.681 -28.148 57.196 1.00 46.23 ? 124 TYR A N 1 ATOM 942 C CA . TYR A 1 123 ? -31.894 -29.250 56.636 1.00 50.58 ? 124 TYR A CA 1 ATOM 943 C C . TYR A 1 123 ? -30.393 -28.983 56.765 1.00 51.81 ? 124 TYR A C 1 ATOM 944 O O . TYR A 1 123 ? -29.578 -29.894 56.592 1.00 46.20 ? 124 TYR A O 1 ATOM 945 C CB . TYR A 1 123 ? -32.261 -29.537 55.159 1.00 49.02 ? 124 TYR A CB 1 ATOM 946 C CG . TYR A 1 123 ? -31.768 -28.498 54.167 1.00 44.27 ? 124 TYR A CG 1 ATOM 947 C CD1 . TYR A 1 123 ? -30.478 -28.553 53.646 1.00 45.85 ? 124 TYR A CD1 1 ATOM 948 C CD2 . TYR A 1 123 ? -32.591 -27.458 53.756 1.00 47.74 ? 124 TYR A CD2 1 ATOM 949 C CE1 . TYR A 1 123 ? -30.019 -27.585 52.743 1.00 49.97 ? 124 TYR A CE1 1 ATOM 950 C CE2 . TYR A 1 123 ? -32.139 -26.484 52.844 1.00 48.03 ? 124 TYR A CE2 1 ATOM 951 C CZ . TYR A 1 123 ? -30.858 -26.554 52.349 1.00 46.68 ? 124 TYR A CZ 1 ATOM 952 O OH . TYR A 1 123 ? -30.418 -25.595 51.467 1.00 50.46 ? 124 TYR A OH 1 ATOM 953 N N . SER A 1 124 ? -30.034 -27.729 57.037 1.00 45.04 ? 125 SER A N 1 ATOM 954 C CA . SER A 1 124 ? -28.632 -27.341 57.131 1.00 49.95 ? 125 SER A CA 1 ATOM 955 C C . SER A 1 124 ? -28.414 -26.230 58.179 1.00 53.91 ? 125 SER A C 1 ATOM 956 O O . SER A 1 124 ? -29.376 -25.689 58.731 1.00 51.01 ? 125 SER A O 1 ATOM 957 C CB . SER A 1 124 ? -28.154 -26.841 55.769 1.00 44.88 ? 125 SER A CB 1 ATOM 958 O OG . SER A 1 124 ? -28.801 -25.620 55.481 1.00 43.49 ? 125 SER A OG 1 ATOM 959 N N . GLY A 1 125 ? -27.150 -25.880 58.427 1.00 46.75 ? 126 GLY A N 1 ATOM 960 C CA . GLY A 1 125 ? -26.818 -24.755 59.284 1.00 45.25 ? 126 GLY A CA 1 ATOM 961 C C . GLY A 1 125 ? -25.788 -25.097 60.354 1.00 50.26 ? 126 GLY A C 1 ATOM 962 O O . GLY A 1 125 ? -25.540 -26.272 60.651 1.00 44.35 ? 126 GLY A O 1 ATOM 963 N N . ALA A 1 126 ? -25.172 -24.069 60.927 1.00 45.73 ? 127 ALA A N 1 ATOM 964 C CA . ALA A 1 126 ? -24.141 -24.278 61.932 1.00 51.61 ? 127 ALA A CA 1 ATOM 965 C C . ALA A 1 126 ? -23.817 -22.981 62.678 1.00 54.49 ? 127 ALA A C 1 ATOM 966 O O . ALA A 1 126 ? -23.856 -21.892 62.096 1.00 54.54 ? 127 ALA A O 1 ATOM 967 C CB . ALA A 1 126 ? -22.899 -24.861 61.296 1.00 43.54 ? 127 ALA A CB 1 ATOM 968 N N . SER A 1 127 ? -23.500 -23.093 63.966 1.00 48.86 ? 128 SER A N 1 ATOM 969 C CA . SER A 1 127 ? -23.273 -21.894 64.784 1.00 52.99 ? 128 SER A CA 1 ATOM 970 C C . SER A 1 127 ? -21.873 -21.343 64.595 1.00 51.01 ? 128 SER A C 1 ATOM 971 O O . SER A 1 127 ? -21.590 -20.223 65.002 1.00 55.69 ? 128 SER A O 1 ATOM 972 C CB . SER A 1 127 ? -23.538 -22.166 66.270 1.00 55.83 ? 128 SER A CB 1 ATOM 973 O OG . SER A 1 127 ? -22.740 -23.241 66.730 1.00 57.78 ? 128 SER A OG 1 ATOM 974 N N . SER A 1 128 ? -21.023 -22.133 63.943 1.00 57.31 ? 129 SER A N 1 ATOM 975 C CA . SER A 1 128 ? -19.621 -21.785 63.715 1.00 57.73 ? 129 SER A CA 1 ATOM 976 C C . SER A 1 128 ? -19.325 -21.013 62.423 1.00 58.10 ? 129 SER A C 1 ATOM 977 O O . SER A 1 128 ? -18.185 -20.639 62.185 1.00 65.72 ? 129 SER A O 1 ATOM 978 C CB . SER A 1 128 ? -18.751 -23.047 63.766 1.00 58.84 ? 129 SER A CB 1 ATOM 979 O OG . SER A 1 128 ? -19.111 -23.994 62.775 1.00 55.26 ? 129 SER A OG 1 ATOM 980 N N . LEU A 1 129 ? -20.335 -20.773 61.592 1.00 62.01 ? 130 LEU A N 1 ATOM 981 C CA . LEU A 1 129 ? -20.126 -20.061 60.326 1.00 56.16 ? 130 LEU A CA 1 ATOM 982 C C . LEU A 1 129 ? -19.629 -18.646 60.575 1.00 62.41 ? 130 LEU A C 1 ATOM 983 O O . LEU A 1 129 ? -20.073 -17.991 61.518 1.00 66.50 ? 130 LEU A O 1 ATOM 984 C CB . LEU A 1 129 ? -21.425 -20.000 59.528 1.00 60.33 ? 130 LEU A CB 1 ATOM 985 C CG . LEU A 1 129 ? -22.124 -21.333 59.269 1.00 59.48 ? 130 LEU A CG 1 ATOM 986 C CD1 . LEU A 1 129 ? -23.401 -21.131 58.473 1.00 54.51 ? 130 LEU A CD1 1 ATOM 987 C CD2 . LEU A 1 129 ? -21.177 -22.279 58.577 1.00 50.59 ? 130 LEU A CD2 1 ATOM 988 N N . ASP A 1 130 ? -18.719 -18.172 59.725 1.00 64.49 ? 131 ASP A N 1 ATOM 989 C CA . ASP A 1 130 ? -18.058 -16.887 59.953 1.00 61.41 ? 131 ASP A CA 1 ATOM 990 C C . ASP A 1 130 ? -19.034 -15.742 60.079 1.00 62.40 ? 131 ASP A C 1 ATOM 991 O O . ASP A 1 130 ? -18.839 -14.834 60.881 1.00 66.61 ? 131 ASP A O 1 ATOM 992 C CB . ASP A 1 130 ? -17.068 -16.568 58.846 1.00 51.96 ? 131 ASP A CB 1 ATOM 993 C CG . ASP A 1 130 ? -16.037 -17.647 58.672 1.00 70.90 ? 131 ASP A CG 1 ATOM 994 O OD1 . ASP A 1 130 ? -15.833 -18.405 59.649 1.00 65.76 ? 131 ASP A OD1 1 ATOM 995 O OD2 . ASP A 1 130 ? -15.442 -17.735 57.563 1.00 68.46 ? 131 ASP A OD2 1 ATOM 996 N N . VAL A 1 131 ? -20.092 -15.794 59.286 1.00 66.40 ? 132 VAL A N 1 ATOM 997 C CA . VAL A 1 131 ? -21.060 -14.709 59.235 1.00 64.53 ? 132 VAL A CA 1 ATOM 998 C C . VAL A 1 131 ? -21.828 -14.576 60.568 1.00 65.39 ? 132 VAL A C 1 ATOM 999 O O . VAL A 1 131 ? -22.494 -13.557 60.807 1.00 62.81 ? 132 VAL A O 1 ATOM 1000 C CB . VAL A 1 131 ? -21.994 -14.873 57.998 1.00 60.43 ? 132 VAL A CB 1 ATOM 1001 C CG1 . VAL A 1 131 ? -22.806 -16.163 58.087 1.00 60.37 ? 132 VAL A CG1 1 ATOM 1002 C CG2 . VAL A 1 131 ? -22.890 -13.666 57.814 1.00 60.69 ? 132 VAL A CG2 1 ATOM 1003 N N . TYR A 1 132 ? -21.688 -15.580 61.447 1.00 62.47 ? 133 TYR A N 1 ATOM 1004 C CA . TYR A 1 132 ? -22.371 -15.594 62.756 1.00 60.18 ? 133 TYR A CA 1 ATOM 1005 C C . TYR A 1 132 ? -21.467 -15.264 63.964 1.00 62.29 ? 133 TYR A C 1 ATOM 1006 O O . TYR A 1 132 ? -21.749 -15.702 65.075 1.00 63.61 ? 133 TYR A O 1 ATOM 1007 C CB . TYR A 1 132 ? -23.004 -16.966 63.015 1.00 54.04 ? 133 TYR A CB 1 ATOM 1008 C CG . TYR A 1 132 ? -24.062 -17.434 62.030 1.00 62.11 ? 133 TYR A CG 1 ATOM 1009 C CD1 . TYR A 1 132 ? -24.874 -16.532 61.342 1.00 56.97 ? 133 TYR A CD1 1 ATOM 1010 C CD2 . TYR A 1 132 ? -24.254 -18.794 61.797 1.00 54.05 ? 133 TYR A CD2 1 ATOM 1011 C CE1 . TYR A 1 132 ? -25.841 -16.979 60.452 1.00 53.65 ? 133 TYR A CE1 1 ATOM 1012 C CE2 . TYR A 1 132 ? -25.214 -19.240 60.921 1.00 56.27 ? 133 TYR A CE2 1 ATOM 1013 C CZ . TYR A 1 132 ? -26.004 -18.339 60.243 1.00 56.91 ? 133 TYR A CZ 1 ATOM 1014 O OH . TYR A 1 132 ? -26.967 -18.820 59.377 1.00 48.84 ? 133 TYR A OH 1 ATOM 1015 N N . ASP A 1 133 ? -20.394 -14.505 63.752 1.00 66.71 ? 134 ASP A N 1 ATOM 1016 C CA . ASP A 1 133 ? -19.403 -14.225 64.796 1.00 58.12 ? 134 ASP A CA 1 ATOM 1017 C C . ASP A 1 133 ? -19.892 -13.236 65.857 1.00 63.94 ? 134 ASP A C 1 ATOM 1018 O O . ASP A 1 133 ? -20.190 -12.064 65.574 1.00 63.28 ? 134 ASP A O 1 ATOM 1019 C CB . ASP A 1 133 ? -18.124 -13.678 64.171 1.00 65.58 ? 134 ASP A CB 1 ATOM 1020 C CG . ASP A 1 133 ? -16.893 -13.919 65.034 1.00 73.79 ? 134 ASP A CG 1 ATOM 1021 O OD1 . ASP A 1 133 ? -17.034 -14.193 66.261 1.00 75.17 ? 134 ASP A OD1 1 ATOM 1022 O OD2 . ASP A 1 133 ? -15.774 -13.835 64.472 1.00 66.09 ? 134 ASP A OD2 1 ATOM 1023 N N . GLY A 1 134 ? -19.927 -13.709 67.099 1.00 68.90 ? 135 GLY A N 1 ATOM 1024 C CA . GLY A 1 134 ? -20.448 -12.921 68.199 1.00 65.18 ? 135 GLY A CA 1 ATOM 1025 C C . GLY A 1 134 ? -19.578 -11.738 68.570 1.00 64.64 ? 135 GLY A C 1 ATOM 1026 O O . GLY A 1 134 ? -20.056 -10.804 69.212 1.00 64.79 ? 135 GLY A O 1 ATOM 1027 N N . ARG A 1 135 ? -18.317 -11.760 68.148 1.00 61.51 ? 136 ARG A N 1 ATOM 1028 C CA . ARG A 1 135 ? -17.312 -10.854 68.710 1.00 66.03 ? 136 ARG A CA 1 ATOM 1029 C C . ARG A 1 135 ? -17.572 -9.353 68.532 1.00 65.80 ? 136 ARG A C 1 ATOM 1030 O O . ARG A 1 135 ? -17.324 -8.575 69.453 1.00 68.32 ? 136 ARG A O 1 ATOM 1031 C CB . ARG A 1 135 ? -15.899 -11.226 68.245 1.00 64.18 ? 136 ARG A CB 1 ATOM 1032 C CG . ARG A 1 135 ? -15.506 -10.648 66.907 1.00 65.70 ? 136 ARG A CG 1 ATOM 1033 C CD . ARG A 1 135 ? -14.072 -10.983 66.569 1.00 62.90 ? 136 ARG A CD 1 ATOM 1034 N NE . ARG A 1 135 ? -13.877 -12.400 66.307 1.00 56.25 ? 136 ARG A NE 1 ATOM 1035 C CZ . ARG A 1 135 ? -12.684 -12.978 66.245 1.00 63.33 ? 136 ARG A CZ 1 ATOM 1036 N NH1 . ARG A 1 135 ? -11.591 -12.253 66.451 1.00 63.68 ? 136 ARG A NH1 1 ATOM 1037 N NH2 . ARG A 1 135 ? -12.579 -14.276 65.990 1.00 61.65 ? 136 ARG A NH2 1 ATOM 1038 N N . PHE A 1 136 ? -18.080 -8.930 67.383 1.00 59.31 ? 137 PHE A N 1 ATOM 1039 C CA . PHE A 1 136 ? -18.202 -7.494 67.164 1.00 61.02 ? 137 PHE A CA 1 ATOM 1040 C C . PHE A 1 136 ? -19.426 -6.947 67.861 1.00 63.43 ? 137 PHE A C 1 ATOM 1041 O O . PHE A 1 136 ? -19.443 -5.807 68.312 1.00 65.29 ? 137 PHE A O 1 ATOM 1042 C CB . PHE A 1 136 ? -18.234 -7.154 65.676 1.00 59.55 ? 137 PHE A CB 1 ATOM 1043 C CG . PHE A 1 136 ? -17.087 -7.731 64.916 1.00 65.86 ? 137 PHE A CG 1 ATOM 1044 C CD1 . PHE A 1 136 ? -17.196 -8.975 64.308 1.00 67.33 ? 137 PHE A CD1 1 ATOM 1045 C CD2 . PHE A 1 136 ? -15.891 -7.044 64.818 1.00 66.58 ? 137 PHE A CD2 1 ATOM 1046 C CE1 . PHE A 1 136 ? -16.132 -9.518 63.610 1.00 68.08 ? 137 PHE A CE1 1 ATOM 1047 C CE2 . PHE A 1 136 ? -14.821 -7.578 64.119 1.00 68.30 ? 137 PHE A CE2 1 ATOM 1048 C CZ . PHE A 1 136 ? -14.940 -8.816 63.514 1.00 70.09 ? 137 PHE A CZ 1 ATOM 1049 N N . LEU A 1 137 ? -20.455 -7.774 67.942 1.00 66.42 ? 138 LEU A N 1 ATOM 1050 C CA . LEU A 1 137 ? -21.714 -7.374 68.552 1.00 66.42 ? 138 LEU A CA 1 ATOM 1051 C C . LEU A 1 137 ? -21.572 -7.248 70.079 1.00 64.92 ? 138 LEU A C 1 ATOM 1052 O O . LEU A 1 137 ? -22.080 -6.308 70.706 1.00 60.38 ? 138 LEU A O 1 ATOM 1053 C CB . LEU A 1 137 ? -22.789 -8.396 68.174 1.00 61.60 ? 138 LEU A CB 1 ATOM 1054 C CG . LEU A 1 137 ? -24.223 -8.143 68.608 1.00 65.59 ? 138 LEU A CG 1 ATOM 1055 C CD1 . LEU A 1 137 ? -24.591 -6.693 68.381 1.00 63.55 ? 138 LEU A CD1 1 ATOM 1056 C CD2 . LEU A 1 137 ? -25.133 -9.060 67.816 1.00 67.39 ? 138 LEU A CD2 1 ATOM 1057 N N . VAL A 1 138 ? -20.870 -8.205 70.671 1.00 62.58 ? 139 VAL A N 1 ATOM 1058 C CA . VAL A 1 138 ? -20.601 -8.176 72.102 1.00 65.14 ? 139 VAL A CA 1 ATOM 1059 C C . VAL A 1 138 ? -19.680 -7.001 72.488 1.00 68.98 ? 139 VAL A C 1 ATOM 1060 O O . VAL A 1 138 ? -19.915 -6.339 73.494 1.00 59.82 ? 139 VAL A O 1 ATOM 1061 C CB . VAL A 1 138 ? -20.011 -9.523 72.589 1.00 60.83 ? 139 VAL A CB 1 ATOM 1062 C CG1 . VAL A 1 138 ? -19.615 -9.441 74.057 1.00 62.65 ? 139 VAL A CG1 1 ATOM 1063 C CG2 . VAL A 1 138 ? -21.008 -10.639 72.368 1.00 53.91 ? 139 VAL A CG2 1 ATOM 1064 N N . GLN A 1 139 ? -18.650 -6.734 71.682 1.00 70.59 ? 140 GLN A N 1 ATOM 1065 C CA . GLN A 1 139 ? -17.735 -5.625 71.961 1.00 64.06 ? 140 GLN A CA 1 ATOM 1066 C C . GLN A 1 139 ? -18.400 -4.264 71.755 1.00 66.83 ? 140 GLN A C 1 ATOM 1067 O O . GLN A 1 139 ? -18.251 -3.364 72.572 1.00 75.92 ? 140 GLN A O 1 ATOM 1068 C CB . GLN A 1 139 ? -16.462 -5.732 71.119 1.00 67.74 ? 140 GLN A CB 1 ATOM 1069 C CG . GLN A 1 139 ? -15.303 -4.857 71.592 1.00 68.69 ? 140 GLN A CG 1 ATOM 1070 C CD . GLN A 1 139 ? -15.453 -3.400 71.182 1.00 76.06 ? 140 GLN A CD 1 ATOM 1071 O OE1 . GLN A 1 139 ? -15.813 -3.103 70.046 1.00 75.63 ? 140 GLN A OE1 1 ATOM 1072 N NE2 . GLN A 1 139 ? -15.188 -2.485 72.112 1.00 70.11 ? 140 GLN A NE2 1 ATOM 1073 N N . ALA A 1 140 ? -19.134 -4.114 70.663 1.00 70.21 ? 141 ALA A N 1 ATOM 1074 C CA . ALA A 1 140 ? -19.751 -2.833 70.332 1.00 68.39 ? 141 ALA A CA 1 ATOM 1075 C C . ALA A 1 140 ? -20.900 -2.451 71.264 1.00 69.03 ? 141 ALA A C 1 ATOM 1076 O O . ALA A 1 140 ? -21.161 -1.266 71.459 1.00 73.61 ? 141 ALA A O 1 ATOM 1077 C CB . ALA A 1 140 ? -20.221 -2.821 68.867 1.00 62.66 ? 141 ALA A CB 1 ATOM 1078 N N . GLU A 1 141 ? -21.587 -3.440 71.836 1.00 69.08 ? 142 GLU A N 1 ATOM 1079 C CA . GLU A 1 141 ? -22.810 -3.162 72.609 1.00 67.86 ? 142 GLU A CA 1 ATOM 1080 C C . GLU A 1 141 ? -22.854 -3.763 74.024 1.00 71.34 ? 142 GLU A C 1 ATOM 1081 O O . GLU A 1 141 ? -23.810 -3.538 74.772 1.00 67.02 ? 142 GLU A O 1 ATOM 1082 C CB . GLU A 1 141 ? -24.046 -3.590 71.819 1.00 70.12 ? 142 GLU A CB 1 ATOM 1083 C CG . GLU A 1 141 ? -24.266 -2.786 70.538 1.00 75.28 ? 142 GLU A CG 1 ATOM 1084 C CD . GLU A 1 141 ? -24.781 -1.375 70.818 1.00 77.09 ? 142 GLU A CD 1 ATOM 1085 O OE1 . GLU A 1 141 ? -25.357 -1.168 71.915 1.00 70.25 ? 142 GLU A OE1 1 ATOM 1086 O OE2 . GLU A 1 141 ? -24.608 -0.483 69.943 1.00 68.38 ? 142 GLU A OE2 1 ATOM 1087 N N . ARG A 1 142 ? -21.813 -4.512 74.377 1.00 69.69 ? 143 ARG A N 1 ATOM 1088 C CA . ARG A 1 142 ? -21.679 -5.112 75.703 1.00 69.32 ? 143 ARG A CA 1 ATOM 1089 C C . ARG A 1 142 ? -22.954 -5.812 76.158 1.00 66.67 ? 143 ARG A C 1 ATOM 1090 O O . ARG A 1 142 ? -23.584 -5.424 77.146 1.00 67.00 ? 143 ARG A O 1 ATOM 1091 C CB . ARG A 1 142 ? -21.167 -4.087 76.725 1.00 70.34 ? 143 ARG A CB 1 ATOM 1092 C CG . ARG A 1 142 ? -19.785 -3.495 76.361 1.00 72.94 ? 143 ARG A CG 1 ATOM 1093 C CD . ARG A 1 142 ? -19.175 -2.633 77.495 1.00 82.44 ? 143 ARG A CD 1 ATOM 1094 N NE . ARG A 1 142 ? -18.249 -3.374 78.359 1.00 77.47 ? 143 ARG A NE 1 ATOM 1095 C CZ . ARG A 1 142 ? -18.516 -3.754 79.611 1.00 82.05 ? 143 ARG A CZ 1 ATOM 1096 N NH1 . ARG A 1 142 ? -19.689 -3.470 80.175 1.00 82.82 ? 143 ARG A NH1 1 ATOM 1097 N NH2 . ARG A 1 142 ? -17.602 -4.422 80.311 1.00 76.64 ? 143 ARG A NH2 1 ATOM 1098 N N . THR A 1 143 ? -23.337 -6.828 75.390 1.00 58.92 ? 144 THR A N 1 ATOM 1099 C CA . THR A 1 143 ? -24.407 -7.746 75.759 1.00 52.20 ? 144 THR A CA 1 ATOM 1100 C C . THR A 1 143 ? -23.727 -9.104 75.817 1.00 53.03 ? 144 THR A C 1 ATOM 1101 O O . THR A 1 143 ? -22.575 -9.227 75.418 1.00 50.82 ? 144 THR A O 1 ATOM 1102 C CB . THR A 1 143 ? -25.531 -7.786 74.694 1.00 66.25 ? 144 THR A CB 1 ATOM 1103 O OG1 . THR A 1 143 ? -25.027 -8.367 73.483 1.00 63.88 ? 144 THR A OG1 1 ATOM 1104 C CG2 . THR A 1 143 ? -26.059 -6.383 74.382 1.00 64.49 ? 144 THR A CG2 1 ATOM 1105 N N . VAL A 1 144 ? -24.412 -10.116 76.333 1.00 52.32 ? 145 VAL A N 1 ATOM 1106 C CA . VAL A 1 144 ? -23.915 -11.485 76.217 1.00 49.68 ? 145 VAL A CA 1 ATOM 1107 C C . VAL A 1 144 ? -24.569 -12.123 74.975 1.00 56.91 ? 145 VAL A C 1 ATOM 1108 O O . VAL A 1 144 ? -25.743 -11.883 74.692 1.00 58.72 ? 145 VAL A O 1 ATOM 1109 C CB . VAL A 1 144 ? -24.196 -12.303 77.509 1.00 53.39 ? 145 VAL A CB 1 ATOM 1110 C CG1 . VAL A 1 144 ? -23.676 -13.721 77.389 1.00 50.43 ? 145 VAL A CG1 1 ATOM 1111 C CG2 . VAL A 1 144 ? -23.549 -11.619 78.709 1.00 52.70 ? 145 VAL A CG2 1 ATOM 1112 N N . LEU A 1 145 ? -23.805 -12.895 74.209 1.00 54.38 ? 146 LEU A N 1 ATOM 1113 C CA . LEU A 1 145 ? -24.332 -13.524 73.004 1.00 49.84 ? 146 LEU A CA 1 ATOM 1114 C C . LEU A 1 145 ? -24.172 -15.027 73.131 1.00 54.61 ? 146 LEU A C 1 ATOM 1115 O O . LEU A 1 145 ? -23.084 -15.523 73.400 1.00 59.36 ? 146 LEU A O 1 ATOM 1116 C CB . LEU A 1 145 ? -23.610 -12.996 71.750 1.00 50.30 ? 146 LEU A CB 1 ATOM 1117 C CG . LEU A 1 145 ? -24.114 -13.156 70.284 1.00 59.21 ? 146 LEU A CG 1 ATOM 1118 C CD1 . LEU A 1 145 ? -23.959 -14.568 69.697 1.00 53.51 ? 146 LEU A CD1 1 ATOM 1119 C CD2 . LEU A 1 145 ? -25.545 -12.676 70.094 1.00 52.76 ? 146 LEU A CD2 1 ATOM 1120 N N . VAL A 1 146 ? -25.271 -15.750 72.956 1.00 53.68 ? 147 VAL A N 1 ATOM 1121 C CA . VAL A 1 146 ? -25.245 -17.205 72.967 1.00 45.54 ? 147 VAL A CA 1 ATOM 1122 C C . VAL A 1 146 ? -25.807 -17.759 71.656 1.00 53.06 ? 147 VAL A C 1 ATOM 1123 O O . VAL A 1 146 ? -26.740 -17.203 71.074 1.00 54.12 ? 147 VAL A O 1 ATOM 1124 C CB . VAL A 1 146 ? -26.062 -17.749 74.159 1.00 48.90 ? 147 VAL A CB 1 ATOM 1125 C CG1 . VAL A 1 146 ? -26.005 -19.266 74.201 1.00 42.99 ? 147 VAL A CG1 1 ATOM 1126 C CG2 . VAL A 1 146 ? -25.551 -17.144 75.471 1.00 41.18 ? 147 VAL A CG2 1 ATOM 1127 N N . SER A 1 147 ? -25.233 -18.852 71.182 1.00 51.49 ? 148 SER A N 1 ATOM 1128 C CA . SER A 1 147 ? -25.759 -19.520 70.009 1.00 51.13 ? 148 SER A CA 1 ATOM 1129 C C . SER A 1 147 ? -25.551 -21.023 70.144 1.00 52.29 ? 148 SER A C 1 ATOM 1130 O O . SER A 1 147 ? -24.499 -21.456 70.589 1.00 55.43 ? 148 SER A O 1 ATOM 1131 C CB . SER A 1 147 ? -25.069 -18.994 68.748 1.00 53.72 ? 148 SER A CB 1 ATOM 1132 O OG . SER A 1 147 ? -23.701 -19.353 68.732 1.00 57.92 ? 148 SER A OG 1 ATOM 1133 N N . MET A 1 148 ? -26.551 -21.819 69.771 1.00 48.38 ? 149 MET A N 1 ATOM 1134 C CA . MET A 1 148 ? -26.411 -23.269 69.827 1.00 45.03 ? 149 MET A CA 1 ATOM 1135 C C . MET A 1 148 ? -26.482 -23.962 68.469 1.00 55.18 ? 149 MET A C 1 ATOM 1136 O O . MET A 1 148 ? -27.047 -23.440 67.502 1.00 54.80 ? 149 MET A O 1 ATOM 1137 C CB . MET A 1 148 ? -27.478 -23.872 70.735 1.00 49.11 ? 149 MET A CB 1 ATOM 1138 C CG . MET A 1 148 ? -28.840 -24.015 70.093 1.00 45.31 ? 149 MET A CG 1 ATOM 1139 S SD . MET A 1 148 ? -29.563 -22.442 69.632 1.00 56.06 ? 149 MET A SD 1 ATOM 1140 C CE . MET A 1 148 ? -30.318 -21.885 71.164 1.00 48.65 ? 149 MET A CE 1 ATOM 1141 N N . ASN A 1 149 ? -25.902 -25.153 68.415 1.00 53.23 ? 150 ASN A N 1 ATOM 1142 C CA . ASN A 1 149 ? -26.171 -26.083 67.335 1.00 50.96 ? 150 ASN A CA 1 ATOM 1143 C C . ASN A 1 149 ? -27.414 -26.889 67.709 1.00 53.32 ? 150 ASN A C 1 ATOM 1144 O O . ASN A 1 149 ? -27.590 -27.264 68.869 1.00 50.62 ? 150 ASN A O 1 ATOM 1145 C CB . ASN A 1 149 ? -24.990 -27.039 67.135 1.00 53.60 ? 150 ASN A CB 1 ATOM 1146 C CG . ASN A 1 149 ? -23.860 -26.425 66.342 1.00 53.25 ? 150 ASN A CG 1 ATOM 1147 O OD1 . ASN A 1 149 ? -23.904 -25.255 65.973 1.00 55.48 ? 150 ASN A OD1 1 ATOM 1148 N ND2 . ASN A 1 149 ? -22.829 -27.216 66.084 1.00 54.86 ? 150 ASN A ND2 1 ATOM 1149 N N . TYR A 1 150 ? -28.279 -27.139 66.732 1.00 50.99 ? 151 TYR A N 1 ATOM 1150 C CA . TYR A 1 150 ? -29.416 -28.031 66.916 1.00 49.80 ? 151 TYR A CA 1 ATOM 1151 C C . TYR A 1 150 ? -29.494 -28.993 65.726 1.00 53.06 ? 151 TYR A C 1 ATOM 1152 O O . TYR A 1 150 ? -29.118 -28.631 64.614 1.00 51.29 ? 151 TYR A O 1 ATOM 1153 C CB . TYR A 1 150 ? -30.718 -27.235 67.069 1.00 47.07 ? 151 TYR A CB 1 ATOM 1154 C CG . TYR A 1 150 ? -31.082 -26.387 65.870 1.00 52.13 ? 151 TYR A CG 1 ATOM 1155 C CD1 . TYR A 1 150 ? -30.735 -25.040 65.815 1.00 47.74 ? 151 TYR A CD1 1 ATOM 1156 C CD2 . TYR A 1 150 ? -31.790 -26.933 64.796 1.00 43.87 ? 151 TYR A CD2 1 ATOM 1157 C CE1 . TYR A 1 150 ? -31.074 -24.264 64.725 1.00 52.27 ? 151 TYR A CE1 1 ATOM 1158 C CE2 . TYR A 1 150 ? -32.132 -26.167 63.708 1.00 45.94 ? 151 TYR A CE2 1 ATOM 1159 C CZ . TYR A 1 150 ? -31.769 -24.844 63.663 1.00 52.31 ? 151 TYR A CZ 1 ATOM 1160 O OH . TYR A 1 150 ? -32.119 -24.099 62.566 1.00 45.48 ? 151 TYR A OH 1 ATOM 1161 N N . ARG A 1 151 ? -29.975 -30.212 65.969 1.00 49.17 ? 152 ARG A N 1 ATOM 1162 C CA . ARG A 1 151 ? -30.049 -31.238 64.934 1.00 46.02 ? 152 ARG A CA 1 ATOM 1163 C C . ARG A 1 151 ? -30.937 -30.840 63.747 1.00 51.56 ? 152 ARG A C 1 ATOM 1164 O O . ARG A 1 151 ? -32.061 -30.380 63.940 1.00 51.32 ? 152 ARG A O 1 ATOM 1165 C CB . ARG A 1 151 ? -30.538 -32.551 65.530 1.00 41.82 ? 152 ARG A CB 1 ATOM 1166 C CG . ARG A 1 151 ? -29.456 -33.388 66.167 1.00 41.40 ? 152 ARG A CG 1 ATOM 1167 C CD . ARG A 1 151 ? -30.074 -34.496 67.018 1.00 49.70 ? 152 ARG A CD 1 ATOM 1168 N NE . ARG A 1 151 ? -30.868 -33.981 68.139 1.00 45.74 ? 152 ARG A NE 1 ATOM 1169 C CZ . ARG A 1 151 ? -31.594 -34.754 68.948 1.00 51.12 ? 152 ARG A CZ 1 ATOM 1170 N NH1 . ARG A 1 151 ? -31.623 -36.064 68.762 1.00 48.81 ? 152 ARG A NH1 1 ATOM 1171 N NH2 . ARG A 1 151 ? -32.301 -34.229 69.943 1.00 49.04 ? 152 ARG A NH2 1 ATOM 1172 N N . VAL A 1 152 ? -30.419 -31.021 62.527 1.00 51.96 ? 153 VAL A N 1 ATOM 1173 C CA . VAL A 1 152 ? -31.157 -30.719 61.288 1.00 49.78 ? 153 VAL A CA 1 ATOM 1174 C C . VAL A 1 152 ? -31.467 -31.976 60.457 1.00 48.31 ? 153 VAL A C 1 ATOM 1175 O O . VAL A 1 152 ? -30.999 -33.071 60.760 1.00 52.42 ? 153 VAL A O 1 ATOM 1176 C CB . VAL A 1 152 ? -30.384 -29.730 60.387 1.00 44.10 ? 153 VAL A CB 1 ATOM 1177 C CG1 . VAL A 1 152 ? -30.340 -28.350 61.013 1.00 43.79 ? 153 VAL A CG1 1 ATOM 1178 C CG2 . VAL A 1 152 ? -28.990 -30.255 60.104 1.00 42.67 ? 153 VAL A CG2 1 ATOM 1179 N N . GLY A 1 153 ? -32.256 -31.811 59.400 1.00 53.04 ? 154 GLY A N 1 ATOM 1180 C CA . GLY A 1 153 ? -32.566 -32.918 58.515 1.00 52.74 ? 154 GLY A CA 1 ATOM 1181 C C . GLY A 1 153 ? -33.288 -34.041 59.243 1.00 54.64 ? 154 GLY A C 1 ATOM 1182 O O . GLY A 1 153 ? -34.047 -33.783 60.181 1.00 53.01 ? 154 GLY A O 1 ATOM 1183 N N . ALA A 1 154 ? -33.071 -35.284 58.810 1.00 49.50 ? 155 ALA A N 1 ATOM 1184 C CA . ALA A 1 154 ? -33.757 -36.409 59.431 1.00 55.12 ? 155 ALA A CA 1 ATOM 1185 C C . ALA A 1 154 ? -33.425 -36.535 60.935 1.00 57.48 ? 155 ALA A C 1 ATOM 1186 O O . ALA A 1 154 ? -34.263 -36.924 61.741 1.00 49.98 ? 155 ALA A O 1 ATOM 1187 C CB . ALA A 1 154 ? -33.430 -37.687 58.714 1.00 36.30 ? 155 ALA A CB 1 ATOM 1188 N N . PHE A 1 155 ? -32.197 -36.212 61.306 1.00 51.32 ? 156 PHE A N 1 ATOM 1189 C CA . PHE A 1 155 ? -31.773 -36.429 62.669 1.00 53.82 ? 156 PHE A CA 1 ATOM 1190 C C . PHE A 1 155 ? -32.565 -35.532 63.613 1.00 49.27 ? 156 PHE A C 1 ATOM 1191 O O . PHE A 1 155 ? -32.944 -35.945 64.701 1.00 51.99 ? 156 PHE A O 1 ATOM 1192 C CB . PHE A 1 155 ? -30.269 -36.211 62.773 1.00 52.75 ? 156 PHE A CB 1 ATOM 1193 C CG . PHE A 1 155 ? -29.501 -36.945 61.721 1.00 54.43 ? 156 PHE A CG 1 ATOM 1194 C CD1 . PHE A 1 155 ? -29.285 -36.368 60.474 1.00 53.39 ? 156 PHE A CD1 1 ATOM 1195 C CD2 . PHE A 1 155 ? -29.023 -38.224 61.958 1.00 52.51 ? 156 PHE A CD2 1 ATOM 1196 C CE1 . PHE A 1 155 ? -28.590 -37.052 59.490 1.00 53.38 ? 156 PHE A CE1 1 ATOM 1197 C CE2 . PHE A 1 155 ? -28.328 -38.911 60.980 1.00 57.02 ? 156 PHE A CE2 1 ATOM 1198 C CZ . PHE A 1 155 ? -28.111 -38.328 59.744 1.00 53.22 ? 156 PHE A CZ 1 ATOM 1199 N N . GLY A 1 156 ? -32.871 -34.330 63.148 1.00 48.99 ? 157 GLY A N 1 ATOM 1200 C CA . GLY A 1 156 ? -33.636 -33.385 63.925 1.00 49.73 ? 157 GLY A CA 1 ATOM 1201 C C . GLY A 1 156 ? -35.133 -33.452 63.731 1.00 52.23 ? 157 GLY A C 1 ATOM 1202 O O . GLY A 1 156 ? -35.870 -33.232 64.681 1.00 57.25 ? 157 GLY A O 1 ATOM 1203 N N . PHE A 1 157 ? -35.599 -33.743 62.518 1.00 53.10 ? 158 PHE A N 1 ATOM 1204 C CA . PHE A 1 157 ? -37.020 -33.550 62.226 1.00 50.83 ? 158 PHE A CA 1 ATOM 1205 C C . PHE A 1 157 ? -37.830 -34.706 61.605 1.00 51.68 ? 158 PHE A C 1 ATOM 1206 O O . PHE A 1 157 ? -39.025 -34.554 61.366 1.00 50.78 ? 158 PHE A O 1 ATOM 1207 C CB . PHE A 1 157 ? -37.224 -32.246 61.453 1.00 45.44 ? 158 PHE A CB 1 ATOM 1208 C CG . PHE A 1 157 ? -36.745 -31.038 62.194 1.00 47.41 ? 158 PHE A CG 1 ATOM 1209 C CD1 . PHE A 1 157 ? -35.472 -30.541 61.980 1.00 47.75 ? 158 PHE A CD1 1 ATOM 1210 C CD2 . PHE A 1 157 ? -37.555 -30.420 63.141 1.00 48.56 ? 158 PHE A CD2 1 ATOM 1211 C CE1 . PHE A 1 157 ? -35.018 -29.430 62.671 1.00 44.08 ? 158 PHE A CE1 1 ATOM 1212 C CE2 . PHE A 1 157 ? -37.109 -29.319 63.842 1.00 46.93 ? 158 PHE A CE2 1 ATOM 1213 C CZ . PHE A 1 157 ? -35.830 -28.820 63.608 1.00 46.56 ? 158 PHE A CZ 1 ATOM 1214 N N . LEU A 1 158 ? -37.209 -35.858 61.379 1.00 50.67 ? 159 LEU A N 1 ATOM 1215 C CA . LEU A 1 158 ? -37.972 -37.033 60.951 1.00 54.10 ? 159 LEU A CA 1 ATOM 1216 C C . LEU A 1 158 ? -38.923 -37.436 62.068 1.00 57.96 ? 159 LEU A C 1 ATOM 1217 O O . LEU A 1 158 ? -38.503 -37.645 63.205 1.00 57.03 ? 159 LEU A O 1 ATOM 1218 C CB . LEU A 1 158 ? -37.061 -38.212 60.565 1.00 56.15 ? 159 LEU A CB 1 ATOM 1219 C CG . LEU A 1 158 ? -37.642 -39.574 60.131 1.00 54.37 ? 159 LEU A CG 1 ATOM 1220 C CD1 . LEU A 1 158 ? -36.658 -40.282 59.242 1.00 54.27 ? 159 LEU A CD1 1 ATOM 1221 C CD2 . LEU A 1 158 ? -37.956 -40.492 61.304 1.00 60.54 ? 159 LEU A CD2 1 ATOM 1222 N N . ALA A 1 159 ? -40.200 -37.561 61.724 1.00 57.07 ? 160 ALA A N 1 ATOM 1223 C CA . ALA A 1 159 ? -41.241 -37.873 62.690 1.00 56.29 ? 160 ALA A CA 1 ATOM 1224 C C . ALA A 1 159 ? -42.084 -39.085 62.288 1.00 59.53 ? 160 ALA A C 1 ATOM 1225 O O . ALA A 1 159 ? -42.461 -39.240 61.131 1.00 63.15 ? 160 ALA A O 1 ATOM 1226 C CB . ALA A 1 159 ? -42.139 -36.654 62.896 1.00 49.29 ? 160 ALA A CB 1 ATOM 1227 N N . LEU A 1 160 ? -42.365 -39.946 63.257 1.00 62.19 ? 161 LEU A N 1 ATOM 1228 C CA . LEU A 1 160 ? -43.426 -40.930 63.128 1.00 58.57 ? 161 LEU A CA 1 ATOM 1229 C C . LEU A 1 160 ? -44.420 -40.582 64.208 1.00 64.38 ? 161 LEU A C 1 ATOM 1230 O O . LEU A 1 160 ? -44.396 -41.190 65.281 1.00 71.36 ? 161 LEU A O 1 ATOM 1231 C CB . LEU A 1 160 ? -42.894 -42.339 63.346 1.00 59.93 ? 161 LEU A CB 1 ATOM 1232 C CG . LEU A 1 160 ? -42.092 -42.962 62.205 1.00 64.82 ? 161 LEU A CG 1 ATOM 1233 C CD1 . LEU A 1 160 ? -41.621 -44.327 62.623 1.00 62.83 ? 161 LEU A CD1 1 ATOM 1234 C CD2 . LEU A 1 160 ? -42.941 -43.054 60.941 1.00 60.44 ? 161 LEU A CD2 1 ATOM 1235 N N . PRO A 1 161 ? -45.283 -39.580 63.938 1.00 68.87 ? 162 PRO A N 1 ATOM 1236 C CA . PRO A 1 161 ? -46.067 -38.904 64.985 1.00 68.80 ? 162 PRO A CA 1 ATOM 1237 C C . PRO A 1 161 ? -46.802 -39.898 65.852 1.00 70.88 ? 162 PRO A C 1 ATOM 1238 O O . PRO A 1 161 ? -47.448 -40.808 65.331 1.00 72.12 ? 162 PRO A O 1 ATOM 1239 C CB . PRO A 1 161 ? -47.067 -38.057 64.197 1.00 66.33 ? 162 PRO A CB 1 ATOM 1240 C CG . PRO A 1 161 ? -46.418 -37.840 62.877 1.00 71.00 ? 162 PRO A CG 1 ATOM 1241 C CD . PRO A 1 161 ? -45.625 -39.088 62.593 1.00 63.96 ? 162 PRO A CD 1 ATOM 1242 N N . GLY A 1 162 ? -46.674 -39.736 67.163 1.00 71.45 ? 163 GLY A N 1 ATOM 1243 C CA . GLY A 1 162 ? -47.338 -40.618 68.095 1.00 72.01 ? 163 GLY A CA 1 ATOM 1244 C C . GLY A 1 162 ? -46.426 -41.695 68.643 1.00 72.34 ? 163 GLY A C 1 ATOM 1245 O O . GLY A 1 162 ? -46.795 -42.390 69.578 1.00 78.38 ? 163 GLY A O 1 ATOM 1246 N N . SER A 1 163 ? -45.240 -41.849 68.067 1.00 68.01 ? 164 SER A N 1 ATOM 1247 C CA . SER A 1 163 ? -44.303 -42.839 68.581 1.00 63.63 ? 164 SER A CA 1 ATOM 1248 C C . SER A 1 163 ? -43.352 -42.187 69.568 1.00 66.21 ? 164 SER A C 1 ATOM 1249 O O . SER A 1 163 ? -43.157 -40.973 69.552 1.00 66.83 ? 164 SER A O 1 ATOM 1250 C CB . SER A 1 163 ? -43.510 -43.505 67.453 1.00 68.49 ? 164 SER A CB 1 ATOM 1251 O OG . SER A 1 163 ? -42.503 -42.638 66.963 1.00 63.10 ? 164 SER A OG 1 ATOM 1252 N N . ARG A 1 164 ? -42.769 -42.996 70.439 1.00 69.66 ? 165 ARG A N 1 ATOM 1253 C CA . ARG A 1 164 ? -41.796 -42.489 71.380 1.00 71.46 ? 165 ARG A CA 1 ATOM 1254 C C . ARG A 1 164 ? -40.400 -42.599 70.778 1.00 67.44 ? 165 ARG A C 1 ATOM 1255 O O . ARG A 1 164 ? -39.479 -41.891 71.187 1.00 73.78 ? 165 ARG A O 1 ATOM 1256 C CB . ARG A 1 164 ? -41.885 -43.237 72.718 1.00 81.60 ? 165 ARG A CB 1 ATOM 1257 C CG . ARG A 1 164 ? -42.933 -42.671 73.688 1.00 93.45 ? 165 ARG A CG 1 ATOM 1258 C CD . ARG A 1 164 ? -42.998 -43.480 74.990 1.00 96.07 ? 165 ARG A CD 1 ATOM 1259 N NE . ARG A 1 164 ? -43.443 -44.855 74.750 1.00 108.99 ? 165 ARG A NE 1 ATOM 1260 C CZ . ARG A 1 164 ? -43.478 -45.817 75.671 1.00 104.32 ? 165 ARG A CZ 1 ATOM 1261 N NH1 . ARG A 1 164 ? -43.090 -45.576 76.919 1.00 99.88 ? 165 ARG A NH1 1 ATOM 1262 N NH2 . ARG A 1 164 ? -43.900 -47.031 75.341 1.00 100.33 ? 165 ARG A NH2 1 ATOM 1263 N N . GLU A 1 165 ? -40.245 -43.481 69.796 1.00 69.78 ? 166 GLU A N 1 ATOM 1264 C CA . GLU A 1 165 ? -38.933 -43.712 69.188 1.00 68.19 ? 166 GLU A CA 1 ATOM 1265 C C . GLU A 1 165 ? -38.550 -42.656 68.145 1.00 60.42 ? 166 GLU A C 1 ATOM 1266 O O . GLU A 1 165 ? -37.363 -42.440 67.890 1.00 57.57 ? 166 GLU A O 1 ATOM 1267 C CB . GLU A 1 165 ? -38.824 -45.129 68.620 1.00 71.10 ? 166 GLU A CB 1 ATOM 1268 C CG . GLU A 1 165 ? -38.748 -46.215 69.694 1.00 70.28 ? 166 GLU A CG 1 ATOM 1269 C CD . GLU A 1 165 ? -40.092 -46.901 69.932 1.00 88.35 ? 166 GLU A CD 1 ATOM 1270 O OE1 . GLU A 1 165 ? -41.002 -46.747 69.068 1.00 84.49 ? 166 GLU A OE1 1 ATOM 1271 O OE2 . GLU A 1 165 ? -40.230 -47.592 70.980 1.00 82.32 ? 166 GLU A OE2 1 ATOM 1272 N N . ALA A 1 166 ? -39.551 -41.997 67.562 1.00 54.98 ? 167 ALA A N 1 ATOM 1273 C CA . ALA A 1 166 ? -39.316 -40.841 66.702 1.00 58.76 ? 167 ALA A CA 1 ATOM 1274 C C . ALA A 1 166 ? -40.478 -39.856 66.803 1.00 55.56 ? 167 ALA A C 1 ATOM 1275 O O . ALA A 1 166 ? -41.318 -39.781 65.912 1.00 57.04 ? 167 ALA A O 1 ATOM 1276 C CB . ALA A 1 166 ? -39.092 -41.280 65.253 1.00 58.92 ? 167 ALA A CB 1 ATOM 1277 N N . PRO A 1 167 ? -40.541 -39.104 67.910 1.00 64.71 ? 168 PRO A N 1 ATOM 1278 C CA . PRO A 1 167 ? -41.709 -38.232 68.121 1.00 61.65 ? 168 PRO A CA 1 ATOM 1279 C C . PRO A 1 167 ? -41.764 -37.057 67.156 1.00 56.32 ? 168 PRO A C 1 ATOM 1280 O O . PRO A 1 167 ? -42.836 -36.492 66.941 1.00 61.60 ? 168 PRO A O 1 ATOM 1281 C CB . PRO A 1 167 ? -41.507 -37.717 69.549 1.00 48.94 ? 168 PRO A CB 1 ATOM 1282 C CG . PRO A 1 167 ? -40.034 -37.887 69.817 1.00 51.43 ? 168 PRO A CG 1 ATOM 1283 C CD . PRO A 1 167 ? -39.629 -39.111 69.073 1.00 54.37 ? 168 PRO A CD 1 ATOM 1284 N N . GLY A 1 168 ? -40.618 -36.691 66.596 1.00 53.74 ? 169 GLY A N 1 ATOM 1285 C CA . GLY A 1 168 ? -40.514 -35.464 65.831 1.00 47.24 ? 169 GLY A CA 1 ATOM 1286 C C . GLY A 1 168 ? -40.157 -34.222 66.636 1.00 51.65 ? 169 GLY A C 1 ATOM 1287 O O . GLY A 1 168 ? -40.252 -34.200 67.864 1.00 57.65 ? 169 GLY A O 1 ATOM 1288 N N . ASN A 1 169 ? -39.716 -33.197 65.916 1.00 53.93 ? 170 ASN A N 1 ATOM 1289 C CA . ASN A 1 169 ? -39.477 -31.862 66.442 1.00 44.58 ? 170 ASN A CA 1 ATOM 1290 C C . ASN A 1 169 ? -38.269 -31.799 67.367 1.00 56.88 ? 170 ASN A C 1 ATOM 1291 O O . ASN A 1 169 ? -38.064 -30.805 68.075 1.00 52.77 ? 170 ASN A O 1 ATOM 1292 C CB . ASN A 1 169 ? -40.720 -31.347 67.154 1.00 49.29 ? 170 ASN A CB 1 ATOM 1293 C CG . ASN A 1 169 ? -41.819 -30.970 66.199 1.00 51.43 ? 170 ASN A CG 1 ATOM 1294 O OD1 . ASN A 1 169 ? -41.568 -30.428 65.135 1.00 50.49 ? 170 ASN A OD1 1 ATOM 1295 N ND2 . ASN A 1 169 ? -43.052 -31.238 66.585 1.00 58.25 ? 170 ASN A ND2 1 ATOM 1296 N N . VAL A 1 170 ? -37.454 -32.850 67.356 1.00 51.08 ? 171 VAL A N 1 ATOM 1297 C CA . VAL A 1 170 ? -36.421 -32.956 68.371 1.00 47.98 ? 171 VAL A CA 1 ATOM 1298 C C . VAL A 1 170 ? -35.325 -31.903 68.238 1.00 50.16 ? 171 VAL A C 1 ATOM 1299 O O . VAL A 1 170 ? -34.553 -31.685 69.166 1.00 51.16 ? 171 VAL A O 1 ATOM 1300 C CB . VAL A 1 170 ? -35.849 -34.382 68.495 1.00 47.44 ? 171 VAL A CB 1 ATOM 1301 C CG1 . VAL A 1 170 ? -36.984 -35.394 68.728 1.00 46.31 ? 171 VAL A CG1 1 ATOM 1302 C CG2 . VAL A 1 170 ? -35.009 -34.737 67.303 1.00 45.35 ? 171 VAL A CG2 1 ATOM 1303 N N . GLY A 1 171 ? -35.274 -31.225 67.098 1.00 51.26 ? 172 GLY A N 1 ATOM 1304 C CA . GLY A 1 171 ? -34.289 -30.179 66.901 1.00 45.53 ? 172 GLY A CA 1 ATOM 1305 C C . GLY A 1 171 ? -34.739 -28.884 67.538 1.00 46.70 ? 172 GLY A C 1 ATOM 1306 O O . GLY A 1 171 ? -33.919 -28.036 67.881 1.00 44.21 ? 172 GLY A O 1 ATOM 1307 N N . LEU A 1 172 ? -36.052 -28.714 67.644 1.00 40.91 ? 173 LEU A N 1 ATOM 1308 C CA . LEU A 1 172 ? -36.609 -27.609 68.393 1.00 46.48 ? 173 LEU A CA 1 ATOM 1309 C C . LEU A 1 172 ? -36.367 -27.848 69.905 1.00 50.79 ? 173 LEU A C 1 ATOM 1310 O O . LEU A 1 172 ? -36.075 -26.906 70.641 1.00 43.62 ? 173 LEU A O 1 ATOM 1311 C CB . LEU A 1 172 ? -38.100 -27.462 68.108 1.00 43.13 ? 173 LEU A CB 1 ATOM 1312 C CG . LEU A 1 172 ? -38.497 -27.094 66.684 1.00 53.39 ? 173 LEU A CG 1 ATOM 1313 C CD1 . LEU A 1 172 ? -40.006 -27.094 66.566 1.00 52.48 ? 173 LEU A CD1 1 ATOM 1314 C CD2 . LEU A 1 172 ? -37.934 -25.742 66.296 1.00 50.70 ? 173 LEU A CD2 1 ATOM 1315 N N . LEU A 1 173 ? -36.488 -29.107 70.338 1.00 47.33 ? 174 LEU A N 1 ATOM 1316 C CA . LEU A 1 173 ? -36.149 -29.518 71.693 1.00 45.91 ? 174 LEU A CA 1 ATOM 1317 C C . LEU A 1 173 ? -34.668 -29.303 71.983 1.00 52.32 ? 174 LEU A C 1 ATOM 1318 O O . LEU A 1 173 ? -34.306 -29.014 73.121 1.00 49.34 ? 174 LEU A O 1 ATOM 1319 C CB . LEU A 1 173 ? -36.481 -30.988 71.931 1.00 44.02 ? 174 LEU A CB 1 ATOM 1320 C CG . LEU A 1 173 ? -37.936 -31.423 71.887 1.00 47.36 ? 174 LEU A CG 1 ATOM 1321 C CD1 . LEU A 1 173 ? -38.022 -32.866 72.291 1.00 45.01 ? 174 LEU A CD1 1 ATOM 1322 C CD2 . LEU A 1 173 ? -38.816 -30.558 72.763 1.00 33.08 ? 174 LEU A CD2 1 ATOM 1323 N N . ASP A 1 174 ? -33.811 -29.452 70.971 1.00 47.23 ? 175 ASP A N 1 ATOM 1324 C CA . ASP A 1 174 ? -32.403 -29.118 71.151 1.00 43.02 ? 175 ASP A CA 1 ATOM 1325 C C . ASP A 1 174 ? -32.271 -27.626 71.498 1.00 52.10 ? 175 ASP A C 1 ATOM 1326 O O . ASP A 1 174 ? -31.567 -27.248 72.449 1.00 51.36 ? 175 ASP A O 1 ATOM 1327 C CB . ASP A 1 174 ? -31.566 -29.462 69.911 1.00 45.03 ? 175 ASP A CB 1 ATOM 1328 C CG . ASP A 1 174 ? -31.472 -30.965 69.660 1.00 53.35 ? 175 ASP A CG 1 ATOM 1329 O OD1 . ASP A 1 174 ? -31.856 -31.713 70.579 1.00 51.90 ? 175 ASP A OD1 1 ATOM 1330 O OD2 . ASP A 1 174 ? -31.006 -31.401 68.568 1.00 49.14 ? 175 ASP A OD2 1 ATOM 1331 N N . GLN A 1 175 ? -32.969 -26.789 70.735 1.00 44.27 ? 176 GLN A N 1 ATOM 1332 C CA . GLN A 1 175 ? -32.991 -25.352 70.986 1.00 50.47 ? 176 GLN A CA 1 ATOM 1333 C C . GLN A 1 175 ? -33.490 -25.008 72.391 1.00 50.44 ? 176 GLN A C 1 ATOM 1334 O O . GLN A 1 175 ? -33.014 -24.058 73.011 1.00 51.84 ? 176 GLN A O 1 ATOM 1335 C CB . GLN A 1 175 ? -33.872 -24.634 69.951 1.00 41.22 ? 176 GLN A CB 1 ATOM 1336 C CG . GLN A 1 175 ? -33.317 -24.674 68.555 1.00 47.36 ? 176 GLN A CG 1 ATOM 1337 C CD . GLN A 1 175 ? -34.322 -24.217 67.503 1.00 48.48 ? 176 GLN A CD 1 ATOM 1338 O OE1 . GLN A 1 175 ? -35.396 -23.692 67.824 1.00 46.83 ? 176 GLN A OE1 1 ATOM 1339 N NE2 . GLN A 1 175 ? -33.967 -24.402 66.241 1.00 46.06 ? 176 GLN A NE2 1 ATOM 1340 N N . ARG A 1 176 ? -34.473 -25.764 72.869 1.00 50.27 ? 177 ARG A N 1 ATOM 1341 C CA . ARG A 1 176 ? -35.096 -25.477 74.142 1.00 49.37 ? 177 ARG A CA 1 ATOM 1342 C C . ARG A 1 176 ? -34.173 -25.885 75.301 1.00 51.73 ? 177 ARG A C 1 ATOM 1343 O O . ARG A 1 176 ? -34.126 -25.221 76.336 1.00 48.37 ? 177 ARG A O 1 ATOM 1344 C CB . ARG A 1 176 ? -36.455 -26.165 74.251 1.00 42.70 ? 177 ARG A CB 1 ATOM 1345 C CG . ARG A 1 176 ? -37.117 -25.944 75.606 1.00 44.88 ? 177 ARG A CG 1 ATOM 1346 C CD . ARG A 1 176 ? -38.396 -26.717 75.735 1.00 43.34 ? 177 ARG A CD 1 ATOM 1347 N NE . ARG A 1 176 ? -39.420 -26.067 74.940 1.00 56.68 ? 177 ARG A NE 1 ATOM 1348 C CZ . ARG A 1 176 ? -40.551 -26.639 74.549 1.00 58.00 ? 177 ARG A CZ 1 ATOM 1349 N NH1 . ARG A 1 176 ? -40.831 -27.899 74.878 1.00 54.79 ? 177 ARG A NH1 1 ATOM 1350 N NH2 . ARG A 1 176 ? -41.402 -25.936 73.820 1.00 53.06 ? 177 ARG A NH2 1 ATOM 1351 N N . LEU A 1 177 ? -33.431 -26.970 75.109 1.00 50.50 ? 178 LEU A N 1 ATOM 1352 C CA . LEU A 1 177 ? -32.481 -27.426 76.112 1.00 45.99 ? 178 LEU A CA 1 ATOM 1353 C C . LEU A 1 177 ? -31.373 -26.399 76.300 1.00 48.62 ? 178 LEU A C 1 ATOM 1354 O O . LEU A 1 177 ? -30.950 -26.123 77.426 1.00 56.18 ? 178 LEU A O 1 ATOM 1355 C CB . LEU A 1 177 ? -31.898 -28.778 75.723 1.00 42.39 ? 178 LEU A CB 1 ATOM 1356 C CG . LEU A 1 177 ? -30.987 -29.439 76.753 1.00 48.83 ? 178 LEU A CG 1 ATOM 1357 C CD1 . LEU A 1 177 ? -31.741 -29.624 78.049 1.00 43.75 ? 178 LEU A CD1 1 ATOM 1358 C CD2 . LEU A 1 177 ? -30.491 -30.763 76.229 1.00 46.62 ? 178 LEU A CD2 1 ATOM 1359 N N . ALA A 1 178 ? -30.925 -25.815 75.198 1.00 42.55 ? 179 ALA A N 1 ATOM 1360 C CA . ALA A 1 178 ? -29.915 -24.766 75.230 1.00 41.83 ? 179 ALA A CA 1 ATOM 1361 C C . ALA A 1 178 ? -30.447 -23.514 75.914 1.00 51.56 ? 179 ALA A C 1 ATOM 1362 O O . ALA A 1 178 ? -29.717 -22.868 76.673 1.00 49.96 ? 179 ALA A O 1 ATOM 1363 C CB . ALA A 1 178 ? -29.420 -24.437 73.824 1.00 47.18 ? 179 ALA A CB 1 ATOM 1364 N N . LEU A 1 179 ? -31.707 -23.164 75.650 1.00 44.78 ? 180 LEU A N 1 ATOM 1365 C CA . LEU A 1 179 ? -32.328 -22.073 76.390 1.00 48.18 ? 180 LEU A CA 1 ATOM 1366 C C . LEU A 1 179 ? -32.426 -22.343 77.919 1.00 53.61 ? 180 LEU A C 1 ATOM 1367 O O . LEU A 1 179 ? -32.262 -21.427 78.728 1.00 50.26 ? 180 LEU A O 1 ATOM 1368 C CB . LEU A 1 179 ? -33.693 -21.742 75.816 1.00 45.69 ? 180 LEU A CB 1 ATOM 1369 C CG . LEU A 1 179 ? -33.615 -20.895 74.553 1.00 48.43 ? 180 LEU A CG 1 ATOM 1370 C CD1 . LEU A 1 179 ? -34.950 -20.865 73.848 1.00 45.43 ? 180 LEU A CD1 1 ATOM 1371 C CD2 . LEU A 1 179 ? -33.173 -19.498 74.903 1.00 49.47 ? 180 LEU A CD2 1 ATOM 1372 N N . GLN A 1 180 ? -32.689 -23.592 78.306 1.00 46.78 ? 181 GLN A N 1 ATOM 1373 C CA . GLN A 1 180 ? -32.763 -23.945 79.714 1.00 47.40 ? 181 GLN A CA 1 ATOM 1374 C C . GLN A 1 180 ? -31.363 -23.782 80.337 1.00 54.97 ? 181 GLN A C 1 ATOM 1375 O O . GLN A 1 180 ? -31.226 -23.239 81.439 1.00 50.77 ? 181 GLN A O 1 ATOM 1376 C CB . GLN A 1 180 ? -33.318 -25.373 79.920 1.00 45.35 ? 181 GLN A CB 1 ATOM 1377 C CG . GLN A 1 180 ? -34.843 -25.497 79.752 1.00 46.83 ? 181 GLN A CG 1 ATOM 1378 C CD . GLN A 1 180 ? -35.316 -26.894 79.249 1.00 64.59 ? 181 GLN A CD 1 ATOM 1379 O OE1 . GLN A 1 180 ? -34.514 -27.821 79.060 1.00 59.68 ? 181 GLN A OE1 1 ATOM 1380 N NE2 . GLN A 1 180 ? -36.631 -27.028 79.018 1.00 59.99 ? 181 GLN A NE2 1 ATOM 1381 N N . TRP A 1 181 ? -30.336 -24.233 79.611 1.00 53.48 ? 182 TRP A N 1 ATOM 1382 C CA . TRP A 1 181 ? -28.939 -24.063 80.006 1.00 45.89 ? 182 TRP A CA 1 ATOM 1383 C C . TRP A 1 181 ? -28.614 -22.595 80.263 1.00 52.55 ? 182 TRP A C 1 ATOM 1384 O O . TRP A 1 181 ? -27.895 -22.259 81.204 1.00 55.04 ? 182 TRP A O 1 ATOM 1385 C CB . TRP A 1 181 ? -28.016 -24.612 78.920 1.00 44.95 ? 182 TRP A CB 1 ATOM 1386 C CG . TRP A 1 181 ? -26.540 -24.685 79.276 1.00 48.79 ? 182 TRP A CG 1 ATOM 1387 C CD1 . TRP A 1 181 ? -25.855 -25.792 79.707 1.00 39.03 ? 182 TRP A CD1 1 ATOM 1388 C CD2 . TRP A 1 181 ? -25.570 -23.626 79.178 1.00 46.53 ? 182 TRP A CD2 1 ATOM 1389 N NE1 . TRP A 1 181 ? -24.525 -25.483 79.890 1.00 42.52 ? 182 TRP A NE1 1 ATOM 1390 C CE2 . TRP A 1 181 ? -24.322 -24.164 79.585 1.00 43.66 ? 182 TRP A CE2 1 ATOM 1391 C CE3 . TRP A 1 181 ? -25.634 -22.281 78.795 1.00 44.19 ? 182 TRP A CE3 1 ATOM 1392 C CZ2 . TRP A 1 181 ? -23.146 -23.400 79.625 1.00 40.62 ? 182 TRP A CZ2 1 ATOM 1393 C CZ3 . TRP A 1 181 ? -24.465 -21.517 78.831 1.00 45.63 ? 182 TRP A CZ3 1 ATOM 1394 C CH2 . TRP A 1 181 ? -23.233 -22.085 79.250 1.00 45.03 ? 182 TRP A CH2 1 ATOM 1395 N N . VAL A 1 182 ? -29.150 -21.718 79.425 1.00 52.59 ? 183 VAL A N 1 ATOM 1396 C CA . VAL A 1 182 ? -28.956 -20.283 79.603 1.00 51.73 ? 183 VAL A CA 1 ATOM 1397 C C . VAL A 1 182 ? -29.545 -19.790 80.939 1.00 51.07 ? 183 VAL A C 1 ATOM 1398 O O . VAL A 1 182 ? -28.922 -18.996 81.638 1.00 53.08 ? 183 VAL A O 1 ATOM 1399 C CB . VAL A 1 182 ? -29.510 -19.474 78.391 1.00 51.77 ? 183 VAL A CB 1 ATOM 1400 C CG1 . VAL A 1 182 ? -29.450 -17.978 78.656 1.00 46.56 ? 183 VAL A CG1 1 ATOM 1401 C CG2 . VAL A 1 182 ? -28.735 -19.827 77.123 1.00 50.35 ? 183 VAL A CG2 1 ATOM 1402 N N . GLN A 1 183 ? -30.730 -20.270 81.302 1.00 51.54 ? 184 GLN A N 1 ATOM 1403 C CA . GLN A 1 183 ? -31.352 -19.865 82.561 1.00 50.65 ? 184 GLN A CA 1 ATOM 1404 C C . GLN A 1 183 ? -30.449 -20.191 83.756 1.00 52.67 ? 184 GLN A C 1 ATOM 1405 O O . GLN A 1 183 ? -30.240 -19.359 84.637 1.00 56.75 ? 184 GLN A O 1 ATOM 1406 C CB . GLN A 1 183 ? -32.720 -20.524 82.743 1.00 42.15 ? 184 GLN A CB 1 ATOM 1407 C CG . GLN A 1 183 ? -33.831 -19.861 81.981 1.00 43.41 ? 184 GLN A CG 1 ATOM 1408 C CD . GLN A 1 183 ? -34.047 -18.437 82.411 1.00 49.34 ? 184 GLN A CD 1 ATOM 1409 O OE1 . GLN A 1 183 ? -34.492 -18.173 83.545 1.00 60.37 ? 184 GLN A OE1 1 ATOM 1410 N NE2 . GLN A 1 183 ? -33.734 -17.496 81.517 1.00 41.24 ? 184 GLN A NE2 1 ATOM 1411 N N . GLU A 1 184 ? -29.888 -21.391 83.766 1.00 45.56 ? 185 GLU A N 1 ATOM 1412 C CA . GLU A 1 184 ? -29.119 -21.827 84.910 1.00 52.67 ? 185 GLU A CA 1 ATOM 1413 C C . GLU A 1 184 ? -27.602 -21.582 84.850 1.00 54.22 ? 185 GLU A C 1 ATOM 1414 O O . GLU A 1 184 ? -26.894 -21.938 85.782 1.00 69.78 ? 185 GLU A O 1 ATOM 1415 C CB . GLU A 1 184 ? -29.413 -23.299 85.214 1.00 52.24 ? 185 GLU A CB 1 ATOM 1416 C CG . GLU A 1 184 ? -28.746 -24.254 84.275 1.00 63.78 ? 185 GLU A CG 1 ATOM 1417 C CD . GLU A 1 184 ? -28.476 -25.615 84.908 1.00 79.37 ? 185 GLU A CD 1 ATOM 1418 O OE1 . GLU A 1 184 ? -29.031 -25.889 86.003 1.00 75.47 ? 185 GLU A OE1 1 ATOM 1419 O OE2 . GLU A 1 184 ? -27.705 -26.407 84.302 1.00 78.55 ? 185 GLU A OE2 1 ATOM 1420 N N . ASN A 1 185 ? -27.089 -20.976 83.788 1.00 54.17 ? 186 ASN A N 1 ATOM 1421 C CA . ASN A 1 185 ? -25.642 -20.816 83.674 1.00 37.54 ? 186 ASN A CA 1 ATOM 1422 C C . ASN A 1 185 ? -25.179 -19.486 83.172 1.00 42.08 ? 186 ASN A C 1 ATOM 1423 O O . ASN A 1 185 ? -23.982 -19.245 83.136 1.00 52.18 ? 186 ASN A O 1 ATOM 1424 C CB . ASN A 1 185 ? -25.024 -21.885 82.776 1.00 47.44 ? 186 ASN A CB 1 ATOM 1425 C CG . ASN A 1 185 ? -25.079 -23.252 83.389 1.00 52.24 ? 186 ASN A CG 1 ATOM 1426 O OD1 . ASN A 1 185 ? -24.373 -23.540 84.352 1.00 59.69 ? 186 ASN A OD1 1 ATOM 1427 N ND2 . ASN A 1 185 ? -25.919 -24.109 82.840 1.00 53.29 ? 186 ASN A ND2 1 ATOM 1428 N N . VAL A 1 186 ? -26.091 -18.620 82.752 1.00 45.91 ? 187 VAL A N 1 ATOM 1429 C CA . VAL A 1 186 ? -25.638 -17.437 82.021 1.00 55.77 ? 187 VAL A CA 1 ATOM 1430 C C . VAL A 1 186 ? -25.081 -16.353 82.944 1.00 53.96 ? 187 VAL A C 1 ATOM 1431 O O . VAL A 1 186 ? -24.326 -15.481 82.497 1.00 55.87 ? 187 VAL A O 1 ATOM 1432 C CB . VAL A 1 186 ? -26.705 -16.879 81.039 1.00 49.82 ? 187 VAL A CB 1 ATOM 1433 C CG1 . VAL A 1 186 ? -27.690 -15.971 81.760 1.00 48.70 ? 187 VAL A CG1 1 ATOM 1434 C CG2 . VAL A 1 186 ? -26.040 -16.162 79.873 1.00 41.86 ? 187 VAL A CG2 1 ATOM 1435 N N . ALA A 1 187 ? -25.443 -16.429 84.227 1.00 51.62 ? 188 ALA A N 1 ATOM 1436 C CA . ALA A 1 187 ? -24.904 -15.535 85.261 1.00 49.73 ? 188 ALA A CA 1 ATOM 1437 C C . ALA A 1 187 ? -23.395 -15.676 85.382 1.00 54.14 ? 188 ALA A C 1 ATOM 1438 O O . ALA A 1 187 ? -22.690 -14.677 85.452 1.00 60.37 ? 188 ALA A O 1 ATOM 1439 C CB . ALA A 1 187 ? -25.559 -15.790 86.577 1.00 42.15 ? 188 ALA A CB 1 ATOM 1440 N N . ALA A 1 188 ? -22.904 -16.913 85.357 1.00 54.53 ? 189 ALA A N 1 ATOM 1441 C CA . ALA A 1 188 ? -21.461 -17.197 85.285 1.00 52.13 ? 189 ALA A CA 1 ATOM 1442 C C . ALA A 1 188 ? -20.650 -16.316 84.317 1.00 59.97 ? 189 ALA A C 1 ATOM 1443 O O . ALA A 1 188 ? -19.445 -16.151 84.497 1.00 68.25 ? 189 ALA A O 1 ATOM 1444 C CB . ALA A 1 188 ? -21.220 -18.684 84.966 1.00 41.58 ? 189 ALA A CB 1 ATOM 1445 N N . PHE A 1 189 ? -21.306 -15.752 83.303 1.00 56.11 ? 190 PHE A N 1 ATOM 1446 C CA . PHE A 1 189 ? -20.625 -14.973 82.272 1.00 55.46 ? 190 PHE A CA 1 ATOM 1447 C C . PHE A 1 189 ? -21.012 -13.500 82.386 1.00 59.77 ? 190 PHE A C 1 ATOM 1448 O O . PHE A 1 189 ? -20.514 -12.650 81.637 1.00 57.13 ? 190 PHE A O 1 ATOM 1449 C CB . PHE A 1 189 ? -20.966 -15.502 80.862 1.00 51.40 ? 190 PHE A CB 1 ATOM 1450 C CG . PHE A 1 189 ? -20.681 -16.974 80.673 1.00 51.77 ? 190 PHE A CG 1 ATOM 1451 C CD1 . PHE A 1 189 ? -21.601 -17.932 81.071 1.00 53.86 ? 190 PHE A CD1 1 ATOM 1452 C CD2 . PHE A 1 189 ? -19.493 -17.398 80.098 1.00 52.02 ? 190 PHE A CD2 1 ATOM 1453 C CE1 . PHE A 1 189 ? -21.331 -19.289 80.909 1.00 55.63 ? 190 PHE A CE1 1 ATOM 1454 C CE2 . PHE A 1 189 ? -19.218 -18.747 79.938 1.00 50.84 ? 190 PHE A CE2 1 ATOM 1455 C CZ . PHE A 1 189 ? -20.137 -19.693 80.341 1.00 52.43 ? 190 PHE A CZ 1 ATOM 1456 N N . GLY A 1 190 ? -21.913 -13.203 83.317 1.00 50.90 ? 191 GLY A N 1 ATOM 1457 C CA . GLY A 1 190 ? -22.334 -11.833 83.545 1.00 56.55 ? 191 GLY A CA 1 ATOM 1458 C C . GLY A 1 190 ? -23.677 -11.491 82.941 1.00 58.91 ? 191 GLY A C 1 ATOM 1459 O O . GLY A 1 190 ? -24.074 -10.325 82.896 1.00 59.93 ? 191 GLY A O 1 ATOM 1460 N N . GLY A 1 191 ? -24.390 -12.516 82.492 1.00 58.84 ? 192 GLY A N 1 ATOM 1461 C CA . GLY A 1 191 ? -25.656 -12.312 81.824 1.00 51.82 ? 192 GLY A CA 1 ATOM 1462 C C . GLY A 1 191 ? -26.864 -12.404 82.723 1.00 54.50 ? 192 GLY A C 1 ATOM 1463 O O . GLY A 1 191 ? -26.874 -13.135 83.716 1.00 53.05 ? 192 GLY A O 1 ATOM 1464 N N . ASP A 1 192 ? -27.899 -11.665 82.344 1.00 55.63 ? 193 ASP A N 1 ATOM 1465 C CA . ASP A 1 192 ? -29.152 -11.601 83.090 1.00 52.43 ? 193 ASP A CA 1 ATOM 1466 C C . ASP A 1 192 ? -30.191 -12.544 82.461 1.00 55.54 ? 193 ASP A C 1 ATOM 1467 O O . ASP A 1 192 ? -30.684 -12.294 81.365 1.00 51.17 ? 193 ASP A O 1 ATOM 1468 C CB . ASP A 1 192 ? -29.636 -10.143 83.082 1.00 53.30 ? 193 ASP A CB 1 ATOM 1469 C CG . ASP A 1 192 ? -30.952 -9.939 83.801 1.00 58.89 ? 193 ASP A CG 1 ATOM 1470 O OD1 . ASP A 1 192 ? -31.514 -10.912 84.356 1.00 62.47 ? 193 ASP A OD1 1 ATOM 1471 O OD2 . ASP A 1 192 ? -31.426 -8.778 83.818 1.00 58.15 ? 193 ASP A OD2 1 ATOM 1472 N N . PRO A 1 193 ? -30.531 -13.635 83.166 1.00 58.31 ? 194 PRO A N 1 ATOM 1473 C CA . PRO A 1 193 ? -31.510 -14.612 82.671 1.00 49.44 ? 194 PRO A CA 1 ATOM 1474 C C . PRO A 1 193 ? -32.932 -14.046 82.646 1.00 53.97 ? 194 PRO A C 1 ATOM 1475 O O . PRO A 1 193 ? -33.847 -14.666 82.089 1.00 50.36 ? 194 PRO A O 1 ATOM 1476 C CB . PRO A 1 193 ? -31.416 -15.750 83.701 1.00 51.84 ? 194 PRO A CB 1 ATOM 1477 C CG . PRO A 1 193 ? -30.923 -15.111 84.929 1.00 43.72 ? 194 PRO A CG 1 ATOM 1478 C CD . PRO A 1 193 ? -29.967 -14.038 84.467 1.00 43.15 ? 194 PRO A CD 1 ATOM 1479 N N . THR A 1 194 ? -33.118 -12.879 83.253 1.00 50.52 ? 195 THR A N 1 ATOM 1480 C CA . THR A 1 194 ? -34.423 -12.239 83.256 1.00 49.52 ? 195 THR A CA 1 ATOM 1481 C C . THR A 1 194 ? -34.575 -11.298 82.063 1.00 48.98 ? 195 THR A C 1 ATOM 1482 O O . THR A 1 194 ? -35.634 -10.705 81.878 1.00 53.53 ? 195 THR A O 1 ATOM 1483 C CB . THR A 1 194 ? -34.716 -11.481 84.601 1.00 56.57 ? 195 THR A CB 1 ATOM 1484 O OG1 . THR A 1 194 ? -33.789 -10.402 84.770 1.00 53.36 ? 195 THR A OG1 1 ATOM 1485 C CG2 . THR A 1 194 ? -34.630 -12.412 85.803 1.00 34.87 ? 195 THR A CG2 1 ATOM 1486 N N . SER A 1 195 ? -33.522 -11.175 81.251 1.00 50.11 ? 196 SER A N 1 ATOM 1487 C CA . SER A 1 195 ? -33.580 -10.399 80.002 1.00 55.53 ? 196 SER A CA 1 ATOM 1488 C C . SER A 1 195 ? -32.990 -11.172 78.806 1.00 54.54 ? 196 SER A C 1 ATOM 1489 O O . SER A 1 195 ? -31.855 -10.946 78.387 1.00 50.87 ? 196 SER A O 1 ATOM 1490 C CB . SER A 1 195 ? -32.872 -9.056 80.159 1.00 52.37 ? 196 SER A CB 1 ATOM 1491 O OG . SER A 1 195 ? -33.140 -8.208 79.053 1.00 60.58 ? 196 SER A OG 1 ATOM 1492 N N . VAL A 1 196 ? -33.757 -12.105 78.266 1.00 45.91 ? 197 VAL A N 1 ATOM 1493 C CA . VAL A 1 196 ? -33.244 -12.912 77.174 1.00 54.04 ? 197 VAL A CA 1 ATOM 1494 C C . VAL A 1 196 ? -34.047 -12.673 75.912 1.00 52.26 ? 197 VAL A C 1 ATOM 1495 O O . VAL A 1 196 ? -35.272 -12.852 75.894 1.00 52.55 ? 197 VAL A O 1 ATOM 1496 C CB . VAL A 1 196 ? -33.265 -14.404 77.512 1.00 57.13 ? 197 VAL A CB 1 ATOM 1497 C CG1 . VAL A 1 196 ? -32.728 -15.197 76.352 1.00 42.79 ? 197 VAL A CG1 1 ATOM 1498 C CG2 . VAL A 1 196 ? -32.459 -14.664 78.763 1.00 45.01 ? 197 VAL A CG2 1 ATOM 1499 N N . THR A 1 197 ? -33.355 -12.238 74.867 1.00 51.81 ? 198 THR A N 1 ATOM 1500 C CA . THR A 1 197 ? -33.987 -11.992 73.574 1.00 47.34 ? 198 THR A CA 1 ATOM 1501 C C . THR A 1 197 ? -33.568 -13.050 72.552 1.00 48.94 ? 198 THR A C 1 ATOM 1502 O O . THR A 1 197 ? -32.369 -13.243 72.302 1.00 46.96 ? 198 THR A O 1 ATOM 1503 C CB . THR A 1 197 ? -33.649 -10.590 73.070 1.00 48.22 ? 198 THR A CB 1 ATOM 1504 O OG1 . THR A 1 197 ? -34.369 -9.643 73.859 1.00 56.45 ? 198 THR A OG1 1 ATOM 1505 C CG2 . THR A 1 197 ? -34.043 -10.416 71.598 1.00 55.86 ? 198 THR A CG2 1 ATOM 1506 N N . LEU A 1 198 ? -34.548 -13.759 71.992 1.00 48.29 ? 199 LEU A N 1 ATOM 1507 C CA . LEU A 1 198 ? -34.270 -14.698 70.900 1.00 49.11 ? 199 LEU A CA 1 ATOM 1508 C C . LEU A 1 198 ? -34.235 -13.977 69.573 1.00 48.94 ? 199 LEU A C 1 ATOM 1509 O O . LEU A 1 198 ? -35.135 -13.195 69.265 1.00 48.29 ? 199 LEU A O 1 ATOM 1510 C CB . LEU A 1 198 ? -35.342 -15.776 70.796 1.00 50.70 ? 199 LEU A CB 1 ATOM 1511 C CG . LEU A 1 198 ? -35.548 -16.788 71.915 1.00 55.99 ? 199 LEU A CG 1 ATOM 1512 C CD1 . LEU A 1 198 ? -36.280 -18.005 71.360 1.00 45.61 ? 199 LEU A CD1 1 ATOM 1513 C CD2 . LEU A 1 198 ? -34.213 -17.181 72.519 1.00 51.13 ? 199 LEU A CD2 1 ATOM 1514 N N . PHE A 1 199 ? -33.203 -14.249 68.782 1.00 50.54 ? 200 PHE A N 1 ATOM 1515 C CA . PHE A 1 199 ? -33.201 -13.810 67.383 1.00 47.26 ? 200 PHE A CA 1 ATOM 1516 C C . PHE A 1 199 ? -32.710 -14.883 66.398 1.00 49.14 ? 200 PHE A C 1 ATOM 1517 O O . PHE A 1 199 ? -31.868 -15.726 66.732 1.00 43.93 ? 200 PHE A O 1 ATOM 1518 C CB . PHE A 1 199 ? -32.523 -12.430 67.181 1.00 48.31 ? 200 PHE A CB 1 ATOM 1519 C CG . PHE A 1 199 ? -31.013 -12.429 67.307 1.00 45.79 ? 200 PHE A CG 1 ATOM 1520 C CD1 . PHE A 1 199 ? -30.372 -13.072 68.354 1.00 52.94 ? 200 PHE A CD1 1 ATOM 1521 C CD2 . PHE A 1 199 ? -30.239 -11.746 66.382 1.00 51.66 ? 200 PHE A CD2 1 ATOM 1522 C CE1 . PHE A 1 199 ? -28.983 -13.052 68.449 1.00 57.22 ? 200 PHE A CE1 1 ATOM 1523 C CE2 . PHE A 1 199 ? -28.858 -11.722 66.468 1.00 48.74 ? 200 PHE A CE2 1 ATOM 1524 C CZ . PHE A 1 199 ? -28.229 -12.373 67.495 1.00 53.14 ? 200 PHE A CZ 1 ATOM 1525 N N . GLY A 1 200 ? -33.280 -14.859 65.193 1.00 51.28 ? 201 GLY A N 1 ATOM 1526 C CA . GLY A 1 200 ? -32.977 -15.854 64.174 1.00 51.27 ? 201 GLY A CA 1 ATOM 1527 C C . GLY A 1 200 ? -33.373 -15.437 62.767 1.00 56.11 ? 201 GLY A C 1 ATOM 1528 O O . GLY A 1 200 ? -34.210 -14.558 62.561 1.00 59.24 ? 201 GLY A O 1 ATOM 1529 N N . GLU A 1 201 ? -32.761 -16.076 61.785 1.00 57.37 ? 202 GLU A N 1 ATOM 1530 C CA . GLU A 1 201 ? -33.049 -15.779 60.390 1.00 59.64 ? 202 GLU A CA 1 ATOM 1531 C C . GLU A 1 201 ? -33.565 -17.041 59.708 1.00 55.00 ? 202 GLU A C 1 ATOM 1532 O O . GLU A 1 201 ? -33.125 -18.144 60.038 1.00 52.32 ? 202 GLU A O 1 ATOM 1533 C CB . GLU A 1 201 ? -31.796 -15.240 59.708 1.00 56.78 ? 202 GLU A CB 1 ATOM 1534 C CG . GLU A 1 201 ? -32.028 -14.629 58.370 1.00 56.71 ? 202 GLU A CG 1 ATOM 1535 C CD . GLU A 1 201 ? -31.880 -15.642 57.244 1.00 67.08 ? 202 GLU A CD 1 ATOM 1536 O OE1 . GLU A 1 201 ? -31.351 -16.752 57.500 1.00 65.23 ? 202 GLU A OE1 1 ATOM 1537 O OE2 . GLU A 1 201 ? -32.304 -15.327 56.108 1.00 58.49 ? 202 GLU A OE2 1 ATOM 1538 N N . SER A 1 202 ? -34.532 -16.868 58.802 1.00 57.25 ? 203 SER A N 1 ATOM 1539 C CA . SER A 1 202 ? -35.105 -17.963 57.992 1.00 57.90 ? 203 SER A CA 1 ATOM 1540 C C . SER A 1 202 ? -35.754 -19.040 58.876 1.00 53.64 ? 203 SER A C 1 ATOM 1541 O O . SER A 1 202 ? -36.686 -18.743 59.633 1.00 50.70 ? 203 SER A O 1 ATOM 1542 C CB . SER A 1 202 ? -34.055 -18.552 57.019 1.00 58.33 ? 203 SER A CB 1 ATOM 1543 O OG . SER A 1 202 ? -34.539 -19.681 56.306 1.00 62.68 ? 203 SER A OG 1 ATOM 1544 N N . ALA A 1 203 ? -35.269 -20.279 58.779 1.00 50.95 ? 204 ALA A N 1 ATOM 1545 C CA . ALA A 1 203 ? -35.734 -21.357 59.652 1.00 49.24 ? 204 ALA A CA 1 ATOM 1546 C C . ALA A 1 203 ? -35.496 -20.996 61.128 1.00 53.38 ? 204 ALA A C 1 ATOM 1547 O O . ALA A 1 203 ? -36.244 -21.412 62.016 1.00 51.81 ? 204 ALA A O 1 ATOM 1548 C CB . ALA A 1 203 ? -35.039 -22.674 59.301 1.00 47.71 ? 204 ALA A CB 1 ATOM 1549 N N . GLY A 1 204 ? -34.442 -20.223 61.368 1.00 50.09 ? 205 GLY A N 1 ATOM 1550 C CA . GLY A 1 204 ? -34.162 -19.700 62.680 1.00 51.62 ? 205 GLY A CA 1 ATOM 1551 C C . GLY A 1 204 ? -35.293 -18.826 63.158 1.00 53.25 ? 205 GLY A C 1 ATOM 1552 O O . GLY A 1 204 ? -35.714 -18.955 64.303 1.00 55.41 ? 205 GLY A O 1 ATOM 1553 N N . ALA A 1 205 ? -35.786 -17.935 62.299 1.00 50.64 ? 206 ALA A N 1 ATOM 1554 C CA . ALA A 1 205 ? -36.933 -17.098 62.660 1.00 48.38 ? 206 ALA A CA 1 ATOM 1555 C C . ALA A 1 205 ? -38.196 -17.934 62.876 1.00 53.84 ? 206 ALA A C 1 ATOM 1556 O O . ALA A 1 205 ? -38.961 -17.682 63.822 1.00 53.78 ? 206 ALA A O 1 ATOM 1557 C CB . ALA A 1 205 ? -37.178 -16.025 61.622 1.00 48.22 ? 206 ALA A CB 1 ATOM 1558 N N . ALA A 1 206 ? -38.414 -18.922 62.004 1.00 50.11 ? 207 ALA A N 1 ATOM 1559 C CA . ALA A 1 206 ? -39.529 -19.858 62.169 1.00 50.13 ? 207 ALA A CA 1 ATOM 1560 C C . ALA A 1 206 ? -39.427 -20.555 63.521 1.00 48.79 ? 207 ALA A C 1 ATOM 1561 O O . ALA A 1 206 ? -40.427 -20.709 64.229 1.00 52.08 ? 207 ALA A O 1 ATOM 1562 C CB . ALA A 1 206 ? -39.551 -20.898 61.040 1.00 41.76 ? 207 ALA A CB 1 ATOM 1563 N N . SER A 1 207 ? -38.218 -21.000 63.856 1.00 44.07 ? 208 SER A N 1 ATOM 1564 C CA . SER A 1 207 ? -37.937 -21.559 65.181 1.00 50.74 ? 208 SER A CA 1 ATOM 1565 C C . SER A 1 207 ? -38.378 -20.611 66.320 1.00 46.65 ? 208 SER A C 1 ATOM 1566 O O . SER A 1 207 ? -39.184 -20.995 67.181 1.00 43.70 ? 208 SER A O 1 ATOM 1567 C CB . SER A 1 207 ? -36.457 -21.922 65.301 1.00 49.36 ? 208 SER A CB 1 ATOM 1568 O OG . SER A 1 207 ? -36.145 -23.086 64.545 1.00 52.35 ? 208 SER A OG 1 ATOM 1569 N N . VAL A 1 208 ? -37.891 -19.371 66.282 1.00 40.63 ? 209 VAL A N 1 ATOM 1570 C CA . VAL A 1 208 ? -38.274 -18.358 67.255 1.00 45.68 ? 209 VAL A CA 1 ATOM 1571 C C . VAL A 1 208 ? -39.776 -18.266 67.413 1.00 49.91 ? 209 VAL A C 1 ATOM 1572 O O . VAL A 1 208 ? -40.292 -18.235 68.539 1.00 51.38 ? 209 VAL A O 1 ATOM 1573 C CB . VAL A 1 208 ? -37.783 -16.958 66.873 1.00 48.01 ? 209 VAL A CB 1 ATOM 1574 C CG1 . VAL A 1 208 ? -38.136 -15.985 67.978 1.00 45.96 ? 209 VAL A CG1 1 ATOM 1575 C CG2 . VAL A 1 208 ? -36.286 -16.955 66.609 1.00 48.81 ? 209 VAL A CG2 1 ATOM 1576 N N . GLY A 1 209 ? -40.474 -18.220 66.279 1.00 52.19 ? 210 GLY A N 1 ATOM 1577 C CA . GLY A 1 209 ? -41.920 -18.074 66.273 1.00 47.31 ? 210 GLY A CA 1 ATOM 1578 C C . GLY A 1 209 ? -42.608 -19.257 66.919 1.00 50.62 ? 210 GLY A C 1 ATOM 1579 O O . GLY A 1 209 ? -43.660 -19.116 67.551 1.00 53.10 ? 210 GLY A O 1 ATOM 1580 N N . MET A 1 210 ? -42.010 -20.432 66.773 1.00 48.59 ? 211 MET A N 1 ATOM 1581 C CA . MET A 1 210 ? -42.590 -21.624 67.370 1.00 51.45 ? 211 MET A CA 1 ATOM 1582 C C . MET A 1 210 ? -42.372 -21.681 68.874 1.00 51.74 ? 211 MET A C 1 ATOM 1583 O O . MET A 1 210 ? -43.153 -22.286 69.598 1.00 52.98 ? 211 MET A O 1 ATOM 1584 C CB . MET A 1 210 ? -42.074 -22.874 66.680 1.00 49.32 ? 211 MET A CB 1 ATOM 1585 C CG . MET A 1 210 ? -42.592 -22.948 65.262 1.00 54.65 ? 211 MET A CG 1 ATOM 1586 S SD . MET A 1 210 ? -41.920 -24.320 64.347 1.00 66.61 ? 211 MET A SD 1 ATOM 1587 C CE . MET A 1 210 ? -42.050 -23.692 62.643 1.00 52.35 ? 211 MET A CE 1 ATOM 1588 N N . HIS A 1 211 ? -41.314 -21.039 69.349 1.00 50.97 ? 212 HIS A N 1 ATOM 1589 C CA . HIS A 1 211 ? -41.108 -20.941 70.784 1.00 47.41 ? 212 HIS A CA 1 ATOM 1590 C C . HIS A 1 211 ? -42.132 -19.994 71.382 1.00 50.81 ? 212 HIS A C 1 ATOM 1591 O O . HIS A 1 211 ? -42.581 -20.212 72.501 1.00 54.87 ? 212 HIS A O 1 ATOM 1592 C CB . HIS A 1 211 ? -39.691 -20.499 71.120 1.00 44.62 ? 212 HIS A CB 1 ATOM 1593 C CG . HIS A 1 211 ? -38.663 -21.557 70.874 1.00 45.01 ? 212 HIS A CG 1 ATOM 1594 N ND1 . HIS A 1 211 ? -38.666 -22.764 71.537 1.00 46.45 ? 212 HIS A ND1 1 ATOM 1595 C CD2 . HIS A 1 211 ? -37.602 -21.591 70.034 1.00 44.64 ? 212 HIS A CD2 1 ATOM 1596 C CE1 . HIS A 1 211 ? -37.648 -23.497 71.120 1.00 48.42 ? 212 HIS A CE1 1 ATOM 1597 N NE2 . HIS A 1 211 ? -36.987 -22.809 70.207 1.00 50.24 ? 212 HIS A NE2 1 ATOM 1598 N N . LEU A 1 212 ? -42.520 -18.960 70.638 1.00 49.15 ? 213 LEU A N 1 ATOM 1599 C CA . LEU A 1 212 ? -43.620 -18.098 71.077 1.00 48.18 ? 213 LEU A CA 1 ATOM 1600 C C . LEU A 1 212 ? -44.960 -18.823 71.201 1.00 52.29 ? 213 LEU A C 1 ATOM 1601 O O . LEU A 1 212 ? -45.867 -18.329 71.872 1.00 55.59 ? 213 LEU A O 1 ATOM 1602 C CB . LEU A 1 212 ? -43.808 -16.916 70.135 1.00 44.51 ? 213 LEU A CB 1 ATOM 1603 C CG . LEU A 1 212 ? -42.737 -15.845 70.140 1.00 49.73 ? 213 LEU A CG 1 ATOM 1604 C CD1 . LEU A 1 212 ? -42.915 -14.932 68.944 1.00 50.64 ? 213 LEU A CD1 1 ATOM 1605 C CD2 . LEU A 1 212 ? -42.809 -15.045 71.426 1.00 52.44 ? 213 LEU A CD2 1 ATOM 1606 N N . LEU A 1 213 ? -45.087 -19.983 70.553 1.00 55.72 ? 214 LEU A N 1 ATOM 1607 C CA . LEU A 1 213 ? -46.378 -20.678 70.440 1.00 49.13 ? 214 LEU A CA 1 ATOM 1608 C C . LEU A 1 213 ? -46.411 -21.983 71.207 1.00 51.51 ? 214 LEU A C 1 ATOM 1609 O O . LEU A 1 213 ? -47.421 -22.696 71.209 1.00 56.59 ? 214 LEU A O 1 ATOM 1610 C CB . LEU A 1 213 ? -46.694 -20.947 68.977 1.00 54.44 ? 214 LEU A CB 1 ATOM 1611 C CG . LEU A 1 213 ? -46.755 -19.695 68.116 1.00 50.52 ? 214 LEU A CG 1 ATOM 1612 C CD1 . LEU A 1 213 ? -46.969 -20.116 66.701 1.00 42.36 ? 214 LEU A CD1 1 ATOM 1613 C CD2 . LEU A 1 213 ? -47.880 -18.784 68.587 1.00 46.46 ? 214 LEU A CD2 1 ATOM 1614 N N . SER A 1 214 ? -45.296 -22.282 71.863 1.00 50.61 ? 215 SER A N 1 ATOM 1615 C CA . SER A 1 214 ? -45.155 -23.478 72.676 1.00 46.44 ? 215 SER A CA 1 ATOM 1616 C C . SER A 1 214 ? -44.924 -23.108 74.157 1.00 50.59 ? 215 SER A C 1 ATOM 1617 O O . SER A 1 214 ? -43.793 -22.819 74.555 1.00 50.90 ? 215 SER A O 1 ATOM 1618 C CB . SER A 1 214 ? -43.968 -24.284 72.151 1.00 43.31 ? 215 SER A CB 1 ATOM 1619 O OG . SER A 1 214 ? -44.052 -25.642 72.541 1.00 49.61 ? 215 SER A OG 1 ATOM 1620 N N . PRO A 1 215 ? -45.995 -23.111 74.971 1.00 49.75 ? 216 PRO A N 1 ATOM 1621 C CA . PRO A 1 215 ? -45.934 -22.732 76.401 1.00 45.12 ? 216 PRO A CA 1 ATOM 1622 C C . PRO A 1 215 ? -44.695 -23.207 77.197 1.00 45.35 ? 216 PRO A C 1 ATOM 1623 O O . PRO A 1 215 ? -44.059 -22.366 77.812 1.00 48.06 ? 216 PRO A O 1 ATOM 1624 C CB . PRO A 1 215 ? -47.239 -23.287 76.956 1.00 45.07 ? 216 PRO A CB 1 ATOM 1625 C CG . PRO A 1 215 ? -48.203 -23.120 75.753 1.00 37.85 ? 216 PRO A CG 1 ATOM 1626 C CD . PRO A 1 215 ? -47.375 -23.408 74.533 1.00 40.95 ? 216 PRO A CD 1 ATOM 1627 N N . PRO A 1 216 ? -44.299 -24.487 77.119 1.00 51.02 ? 217 PRO A N 1 ATOM 1628 C CA . PRO A 1 216 ? -43.083 -24.840 77.871 1.00 46.63 ? 217 PRO A CA 1 ATOM 1629 C C . PRO A 1 216 ? -41.830 -23.993 77.556 1.00 48.76 ? 217 PRO A C 1 ATOM 1630 O O . PRO A 1 216 ? -40.834 -24.101 78.273 1.00 55.58 ? 217 PRO A O 1 ATOM 1631 C CB . PRO A 1 216 ? -42.849 -26.306 77.475 1.00 52.80 ? 217 PRO A CB 1 ATOM 1632 C CG . PRO A 1 216 ? -44.234 -26.819 77.109 1.00 47.84 ? 217 PRO A CG 1 ATOM 1633 C CD . PRO A 1 216 ? -44.864 -25.653 76.408 1.00 47.99 ? 217 PRO A CD 1 ATOM 1634 N N . SER A 1 217 ? -41.880 -23.155 76.526 1.00 44.00 ? 218 SER A N 1 ATOM 1635 C CA . SER A 1 217 ? -40.756 -22.288 76.202 1.00 38.72 ? 218 SER A CA 1 ATOM 1636 C C . SER A 1 217 ? -40.938 -20.886 76.770 1.00 44.96 ? 218 SER A C 1 ATOM 1637 O O . SER A 1 217 ? -39.984 -20.115 76.835 1.00 48.06 ? 218 SER A O 1 ATOM 1638 C CB . SER A 1 217 ? -40.556 -22.179 74.678 1.00 43.24 ? 218 SER A CB 1 ATOM 1639 O OG . SER A 1 217 ? -40.205 -23.417 74.073 1.00 44.88 ? 218 SER A OG 1 ATOM 1640 N N . ARG A 1 218 ? -42.154 -20.537 77.175 1.00 38.99 ? 219 ARG A N 1 ATOM 1641 C CA . ARG A 1 218 ? -42.425 -19.139 77.485 1.00 46.28 ? 219 ARG A CA 1 ATOM 1642 C C . ARG A 1 218 ? -41.637 -18.622 78.698 1.00 55.40 ? 219 ARG A C 1 ATOM 1643 O O . ARG A 1 218 ? -41.283 -17.445 78.744 1.00 61.08 ? 219 ARG A O 1 ATOM 1644 C CB . ARG A 1 218 ? -43.930 -18.868 77.604 1.00 46.37 ? 219 ARG A CB 1 ATOM 1645 C CG . ARG A 1 218 ? -44.721 -19.115 76.311 1.00 52.26 ? 219 ARG A CG 1 ATOM 1646 C CD . ARG A 1 218 ? -44.257 -18.244 75.133 1.00 51.90 ? 219 ARG A CD 1 ATOM 1647 N NE . ARG A 1 218 ? -44.397 -16.816 75.426 1.00 57.28 ? 219 ARG A NE 1 ATOM 1648 C CZ . ARG A 1 218 ? -45.454 -16.076 75.106 1.00 58.54 ? 219 ARG A CZ 1 ATOM 1649 N NH1 . ARG A 1 218 ? -46.491 -16.602 74.459 1.00 64.50 ? 219 ARG A NH1 1 ATOM 1650 N NH2 . ARG A 1 218 ? -45.477 -14.796 75.433 1.00 64.16 ? 219 ARG A NH2 1 ATOM 1651 N N . GLY A 1 219 ? -41.320 -19.508 79.644 1.00 50.44 ? 220 GLY A N 1 ATOM 1652 C CA . GLY A 1 219 ? -40.480 -19.140 80.765 1.00 51.72 ? 220 GLY A CA 1 ATOM 1653 C C . GLY A 1 219 ? -39.010 -18.925 80.429 1.00 51.09 ? 220 GLY A C 1 ATOM 1654 O O . GLY A 1 219 ? -38.226 -18.497 81.283 1.00 55.71 ? 220 GLY A O 1 ATOM 1655 N N . LEU A 1 220 ? -38.632 -19.201 79.189 1.00 43.16 ? 221 LEU A N 1 ATOM 1656 C CA . LEU A 1 220 ? -37.230 -19.167 78.803 1.00 45.51 ? 221 LEU A CA 1 ATOM 1657 C C . LEU A 1 220 ? -36.751 -17.911 78.080 1.00 46.19 ? 221 LEU A C 1 ATOM 1658 O O . LEU A 1 220 ? -35.560 -17.813 77.787 1.00 49.85 ? 221 LEU A O 1 ATOM 1659 C CB . LEU A 1 220 ? -36.886 -20.386 77.953 1.00 44.95 ? 221 LEU A CB 1 ATOM 1660 C CG . LEU A 1 220 ? -37.329 -21.696 78.588 1.00 48.84 ? 221 LEU A CG 1 ATOM 1661 C CD1 . LEU A 1 220 ? -37.154 -22.838 77.593 1.00 40.31 ? 221 LEU A CD1 1 ATOM 1662 C CD2 . LEU A 1 220 ? -36.571 -21.958 79.908 1.00 36.01 ? 221 LEU A CD2 1 ATOM 1663 N N . PHE A 1 221 ? -37.635 -16.959 77.781 1.00 42.10 ? 222 PHE A N 1 ATOM 1664 C CA . PHE A 1 221 ? -37.180 -15.728 77.115 1.00 44.48 ? 222 PHE A CA 1 ATOM 1665 C C . PHE A 1 221 ? -38.225 -14.630 77.223 1.00 42.71 ? 222 PHE A C 1 ATOM 1666 O O . PHE A 1 221 ? -39.341 -14.903 77.658 1.00 45.46 ? 222 PHE A O 1 ATOM 1667 C CB . PHE A 1 221 ? -36.812 -15.997 75.642 1.00 50.28 ? 222 PHE A CB 1 ATOM 1668 C CG . PHE A 1 221 ? -38.000 -16.294 74.763 1.00 50.65 ? 222 PHE A CG 1 ATOM 1669 C CD1 . PHE A 1 221 ? -38.617 -17.540 74.803 1.00 46.94 ? 222 PHE A CD1 1 ATOM 1670 C CD2 . PHE A 1 221 ? -38.501 -15.330 73.908 1.00 52.51 ? 222 PHE A CD2 1 ATOM 1671 C CE1 . PHE A 1 221 ? -39.717 -17.813 74.017 1.00 45.77 ? 222 PHE A CE1 1 ATOM 1672 C CE2 . PHE A 1 221 ? -39.600 -15.603 73.104 1.00 59.29 ? 222 PHE A CE2 1 ATOM 1673 C CZ . PHE A 1 221 ? -40.208 -16.840 73.159 1.00 54.00 ? 222 PHE A CZ 1 ATOM 1674 N N . HIS A 1 222 ? -37.877 -13.407 76.811 1.00 40.47 ? 223 HIS A N 1 ATOM 1675 C CA . HIS A 1 222 ? -38.724 -12.229 77.063 1.00 45.80 ? 223 HIS A CA 1 ATOM 1676 C C . HIS A 1 222 ? -39.064 -11.397 75.826 1.00 50.92 ? 223 HIS A C 1 ATOM 1677 O O . HIS A 1 222 ? -40.015 -10.612 75.840 1.00 54.73 ? 223 HIS A O 1 ATOM 1678 C CB . HIS A 1 222 ? -38.070 -11.368 78.158 1.00 42.71 ? 223 HIS A CB 1 ATOM 1679 C CG . HIS A 1 222 ? -37.562 -12.194 79.292 1.00 52.16 ? 223 HIS A CG 1 ATOM 1680 N ND1 . HIS A 1 222 ? -36.275 -12.697 79.325 1.00 53.24 ? 223 HIS A ND1 1 ATOM 1681 C CD2 . HIS A 1 222 ? -38.200 -12.729 80.361 1.00 49.82 ? 223 HIS A CD2 1 ATOM 1682 C CE1 . HIS A 1 222 ? -36.134 -13.460 80.393 1.00 53.85 ? 223 HIS A CE1 1 ATOM 1683 N NE2 . HIS A 1 222 ? -37.286 -13.492 81.042 1.00 52.72 ? 223 HIS A NE2 1 ATOM 1684 N N . ARG A 1 223 ? -38.294 -11.593 74.760 1.00 46.26 ? 224 ARG A N 1 ATOM 1685 C CA . ARG A 1 223 ? -38.409 -10.798 73.543 1.00 49.59 ? 224 ARG A CA 1 ATOM 1686 C C . ARG A 1 223 ? -37.974 -11.627 72.341 1.00 50.97 ? 224 ARG A C 1 ATOM 1687 O O . ARG A 1 223 ? -37.116 -12.508 72.478 1.00 48.80 ? 224 ARG A O 1 ATOM 1688 C CB . ARG A 1 223 ? -37.481 -9.592 73.615 1.00 51.13 ? 224 ARG A CB 1 ATOM 1689 C CG . ARG A 1 223 ? -37.943 -8.457 74.477 1.00 50.57 ? 224 ARG A CG 1 ATOM 1690 C CD . ARG A 1 223 ? -36.801 -7.480 74.679 1.00 48.76 ? 224 ARG A CD 1 ATOM 1691 N NE . ARG A 1 223 ? -37.144 -6.509 75.711 1.00 65.37 ? 224 ARG A NE 1 ATOM 1692 C CZ . ARG A 1 223 ? -37.023 -6.727 77.019 1.00 67.92 ? 224 ARG A CZ 1 ATOM 1693 N NH1 . ARG A 1 223 ? -36.555 -7.889 77.474 1.00 61.57 ? 224 ARG A NH1 1 ATOM 1694 N NH2 . ARG A 1 223 ? -37.373 -5.778 77.876 1.00 70.62 ? 224 ARG A NH2 1 ATOM 1695 N N . ALA A 1 224 ? -38.531 -11.312 71.168 1.00 50.23 ? 225 ALA A N 1 ATOM 1696 C CA . ALA A 1 224 ? -38.241 -12.060 69.932 1.00 50.91 ? 225 ALA A CA 1 ATOM 1697 C C . ALA A 1 224 ? -37.955 -11.182 68.717 1.00 48.49 ? 225 ALA A C 1 ATOM 1698 O O . ALA A 1 224 ? -38.681 -10.219 68.432 1.00 50.44 ? 225 ALA A O 1 ATOM 1699 C CB . ALA A 1 224 ? -39.369 -13.029 69.615 1.00 45.09 ? 225 ALA A CB 1 ATOM 1700 N N . VAL A 1 225 ? -36.874 -11.511 68.021 1.00 45.75 ? 226 VAL A N 1 ATOM 1701 C CA . VAL A 1 225 ? -36.613 -10.957 66.686 1.00 58.04 ? 226 VAL A CA 1 ATOM 1702 C C . VAL A 1 225 ? -36.732 -12.032 65.597 1.00 51.77 ? 226 VAL A C 1 ATOM 1703 O O . VAL A 1 225 ? -36.041 -13.055 65.641 1.00 53.85 ? 226 VAL A O 1 ATOM 1704 C CB . VAL A 1 225 ? -35.225 -10.304 66.579 1.00 54.90 ? 226 VAL A CB 1 ATOM 1705 C CG1 . VAL A 1 225 ? -35.039 -9.695 65.189 1.00 47.86 ? 226 VAL A CG1 1 ATOM 1706 C CG2 . VAL A 1 225 ? -35.059 -9.244 67.659 1.00 51.26 ? 226 VAL A CG2 1 ATOM 1707 N N . LEU A 1 226 ? -37.620 -11.814 64.633 1.00 49.77 ? 227 LEU A N 1 ATOM 1708 C CA . LEU A 1 226 ? -37.789 -12.770 63.537 1.00 49.00 ? 227 LEU A CA 1 ATOM 1709 C C . LEU A 1 226 ? -37.319 -12.143 62.222 1.00 51.99 ? 227 LEU A C 1 ATOM 1710 O O . LEU A 1 226 ? -37.926 -11.193 61.736 1.00 53.13 ? 227 LEU A O 1 ATOM 1711 C CB . LEU A 1 226 ? -39.246 -13.223 63.431 1.00 43.33 ? 227 LEU A CB 1 ATOM 1712 C CG . LEU A 1 226 ? -39.830 -14.085 64.548 1.00 50.81 ? 227 LEU A CG 1 ATOM 1713 C CD1 . LEU A 1 226 ? -40.316 -13.219 65.712 1.00 53.19 ? 227 LEU A CD1 1 ATOM 1714 C CD2 . LEU A 1 226 ? -40.955 -14.962 64.037 1.00 50.25 ? 227 LEU A CD2 1 ATOM 1715 N N . GLN A 1 227 ? -36.223 -12.653 61.670 1.00 46.61 ? 228 GLN A N 1 ATOM 1716 C CA . GLN A 1 227 ? -35.669 -12.118 60.423 1.00 56.48 ? 228 GLN A CA 1 ATOM 1717 C C . GLN A 1 227 ? -35.899 -13.045 59.220 1.00 56.58 ? 228 GLN A C 1 ATOM 1718 O O . GLN A 1 227 ? -35.387 -14.169 59.194 1.00 50.20 ? 228 GLN A O 1 ATOM 1719 C CB . GLN A 1 227 ? -34.173 -11.858 60.583 1.00 61.38 ? 228 GLN A CB 1 ATOM 1720 C CG . GLN A 1 227 ? -33.832 -11.005 61.785 1.00 58.43 ? 228 GLN A CG 1 ATOM 1721 C CD . GLN A 1 227 ? -32.350 -11.022 62.134 1.00 66.50 ? 228 GLN A CD 1 ATOM 1722 O OE1 . GLN A 1 227 ? -31.982 -10.883 63.307 1.00 63.27 ? 228 GLN A OE1 1 ATOM 1723 N NE2 . GLN A 1 227 ? -31.492 -11.180 61.122 1.00 57.31 ? 228 GLN A NE2 1 ATOM 1724 N N . SER A 1 228 ? -36.672 -12.562 58.241 1.00 52.82 ? 229 SER A N 1 ATOM 1725 C CA . SER A 1 228 ? -36.956 -13.297 57.002 1.00 56.28 ? 229 SER A CA 1 ATOM 1726 C C . SER A 1 228 ? -37.575 -14.680 57.183 1.00 54.23 ? 229 SER A C 1 ATOM 1727 O O . SER A 1 228 ? -37.221 -15.609 56.452 1.00 54.80 ? 229 SER A O 1 ATOM 1728 C CB . SER A 1 228 ? -35.690 -13.454 56.152 1.00 53.18 ? 229 SER A CB 1 ATOM 1729 O OG . SER A 1 228 ? -35.242 -12.200 55.680 1.00 65.85 ? 229 SER A OG 1 ATOM 1730 N N . GLY A 1 229 ? -38.499 -14.824 58.126 1.00 47.62 ? 230 GLY A N 1 ATOM 1731 C CA . GLY A 1 229 ? -39.084 -16.129 58.391 1.00 46.21 ? 230 GLY A CA 1 ATOM 1732 C C . GLY A 1 229 ? -40.200 -16.079 59.412 1.00 51.32 ? 230 GLY A C 1 ATOM 1733 O O . GLY A 1 229 ? -40.265 -15.163 60.229 1.00 55.57 ? 230 GLY A O 1 ATOM 1734 N N . ALA A 1 230 ? -41.073 -17.076 59.388 1.00 46.54 ? 231 ALA A N 1 ATOM 1735 C CA . ALA A 1 230 ? -42.227 -17.074 60.271 1.00 46.06 ? 231 ALA A CA 1 ATOM 1736 C C . ALA A 1 230 ? -42.720 -18.505 60.425 1.00 52.03 ? 231 ALA A C 1 ATOM 1737 O O . ALA A 1 230 ? -42.612 -19.290 59.491 1.00 48.66 ? 231 ALA A O 1 ATOM 1738 C CB . ALA A 1 230 ? -43.328 -16.158 59.716 1.00 39.93 ? 231 ALA A CB 1 ATOM 1739 N N . PRO A 1 231 ? -43.218 -18.868 61.626 1.00 55.49 ? 232 PRO A N 1 ATOM 1740 C CA . PRO A 1 231 ? -43.657 -20.259 61.808 1.00 56.38 ? 232 PRO A CA 1 ATOM 1741 C C . PRO A 1 231 ? -44.807 -20.630 60.861 1.00 50.85 ? 232 PRO A C 1 ATOM 1742 O O . PRO A 1 231 ? -44.898 -21.777 60.436 1.00 60.35 ? 232 PRO A O 1 ATOM 1743 C CB . PRO A 1 231 ? -44.097 -20.309 63.289 1.00 46.40 ? 232 PRO A CB 1 ATOM 1744 C CG . PRO A 1 231 ? -44.394 -18.890 63.648 1.00 47.91 ? 232 PRO A CG 1 ATOM 1745 C CD . PRO A 1 231 ? -43.441 -18.046 62.835 1.00 47.22 ? 232 PRO A CD 1 ATOM 1746 N N . ASN A 1 232 ? -45.652 -19.659 60.528 1.00 50.12 ? 233 ASN A N 1 ATOM 1747 C CA . ASN A 1 232 ? -46.804 -19.883 59.654 1.00 47.92 ? 233 ASN A CA 1 ATOM 1748 C C . ASN A 1 232 ? -46.461 -19.857 58.148 1.00 57.03 ? 233 ASN A C 1 ATOM 1749 O O . ASN A 1 232 ? -47.348 -19.800 57.302 1.00 63.64 ? 233 ASN A O 1 ATOM 1750 C CB . ASN A 1 232 ? -47.921 -18.874 59.972 1.00 45.00 ? 233 ASN A CB 1 ATOM 1751 C CG . ASN A 1 232 ? -47.460 -17.423 59.826 1.00 50.48 ? 233 ASN A CG 1 ATOM 1752 O OD1 . ASN A 1 232 ? -46.342 -17.087 60.189 1.00 50.84 ? 233 ASN A OD1 1 ATOM 1753 N ND2 . ASN A 1 232 ? -48.307 -16.571 59.258 1.00 56.12 ? 233 ASN A ND2 1 ATOM 1754 N N . GLY A 1 233 ? -45.176 -19.899 57.814 1.00 57.10 ? 234 GLY A N 1 ATOM 1755 C CA . GLY A 1 233 ? -44.750 -20.062 56.436 1.00 54.10 ? 234 GLY A CA 1 ATOM 1756 C C . GLY A 1 233 ? -45.133 -21.420 55.855 1.00 58.50 ? 234 GLY A C 1 ATOM 1757 O O . GLY A 1 233 ? -45.101 -22.417 56.559 1.00 63.03 ? 234 GLY A O 1 ATOM 1758 N N . PRO A 1 234 ? -45.470 -21.470 54.552 1.00 58.70 ? 235 PRO A N 1 ATOM 1759 C CA . PRO A 1 234 ? -45.907 -22.707 53.891 1.00 54.23 ? 235 PRO A CA 1 ATOM 1760 C C . PRO A 1 234 ? -44.827 -23.795 53.828 1.00 56.20 ? 235 PRO A C 1 ATOM 1761 O O . PRO A 1 234 ? -45.155 -24.970 53.648 1.00 53.00 ? 235 PRO A O 1 ATOM 1762 C CB . PRO A 1 234 ? -46.295 -22.234 52.486 1.00 52.09 ? 235 PRO A CB 1 ATOM 1763 C CG . PRO A 1 234 ? -45.534 -20.993 52.265 1.00 50.16 ? 235 PRO A CG 1 ATOM 1764 C CD . PRO A 1 234 ? -45.415 -20.337 53.615 1.00 54.83 ? 235 PRO A CD 1 ATOM 1765 N N . TRP A 1 235 ? -43.566 -23.406 53.993 1.00 53.76 ? 236 TRP A N 1 ATOM 1766 C CA . TRP A 1 235 ? -42.452 -24.351 54.053 1.00 49.47 ? 236 TRP A CA 1 ATOM 1767 C C . TRP A 1 235 ? -42.102 -24.789 55.490 1.00 54.70 ? 236 TRP A C 1 ATOM 1768 O O . TRP A 1 235 ? -41.353 -25.753 55.670 1.00 55.52 ? 236 TRP A O 1 ATOM 1769 C CB . TRP A 1 235 ? -41.220 -23.700 53.431 1.00 45.11 ? 236 TRP A CB 1 ATOM 1770 C CG . TRP A 1 235 ? -41.008 -22.354 54.001 1.00 51.42 ? 236 TRP A CG 1 ATOM 1771 C CD1 . TRP A 1 235 ? -41.553 -21.177 53.564 1.00 51.07 ? 236 TRP A CD1 1 ATOM 1772 C CD2 . TRP A 1 235 ? -40.250 -22.035 55.174 1.00 57.21 ? 236 TRP A CD2 1 ATOM 1773 N NE1 . TRP A 1 235 ? -41.158 -20.139 54.380 1.00 54.83 ? 236 TRP A NE1 1 ATOM 1774 C CE2 . TRP A 1 235 ? -40.360 -20.641 55.376 1.00 54.71 ? 236 TRP A CE2 1 ATOM 1775 C CE3 . TRP A 1 235 ? -39.476 -22.791 56.066 1.00 50.36 ? 236 TRP A CE3 1 ATOM 1776 C CZ2 . TRP A 1 235 ? -39.724 -19.992 56.426 1.00 53.42 ? 236 TRP A CZ2 1 ATOM 1777 C CZ3 . TRP A 1 235 ? -38.853 -22.148 57.099 1.00 50.12 ? 236 TRP A CZ3 1 ATOM 1778 C CH2 . TRP A 1 235 ? -38.976 -20.759 57.274 1.00 51.56 ? 236 TRP A CH2 1 ATOM 1779 N N . ALA A 1 236 ? -42.624 -24.083 56.502 1.00 52.67 ? 237 ALA A N 1 ATOM 1780 C CA . ALA A 1 236 ? -42.116 -24.200 57.898 1.00 48.25 ? 237 ALA A CA 1 ATOM 1781 C C . ALA A 1 236 ? -42.668 -25.362 58.719 1.00 51.12 ? 237 ALA A C 1 ATOM 1782 O O . ALA A 1 236 ? -41.993 -25.877 59.605 1.00 51.36 ? 237 ALA A O 1 ATOM 1783 C CB . ALA A 1 236 ? -42.299 -22.892 58.667 1.00 43.05 ? 237 ALA A CB 1 ATOM 1784 N N . THR A 1 237 ? -43.902 -25.765 58.446 1.00 55.69 ? 238 THR A N 1 ATOM 1785 C CA . THR A 1 237 ? -44.461 -26.927 59.119 1.00 45.66 ? 238 THR A CA 1 ATOM 1786 C C . THR A 1 237 ? -45.061 -27.929 58.151 1.00 50.36 ? 238 THR A C 1 ATOM 1787 O O . THR A 1 237 ? -45.240 -27.655 56.977 1.00 53.57 ? 238 THR A O 1 ATOM 1788 C CB . THR A 1 237 ? -45.529 -26.538 60.159 1.00 50.44 ? 238 THR A CB 1 ATOM 1789 O OG1 . THR A 1 237 ? -46.576 -25.788 59.524 1.00 51.91 ? 238 THR A OG1 1 ATOM 1790 C CG2 . THR A 1 237 ? -44.894 -25.704 61.294 1.00 51.44 ? 238 THR A CG2 1 ATOM 1791 N N . VAL A 1 238 ? -45.393 -29.093 58.681 1.00 57.88 ? 239 VAL A N 1 ATOM 1792 C CA . VAL A 1 238 ? -45.899 -30.199 57.895 1.00 56.46 ? 239 VAL A CA 1 ATOM 1793 C C . VAL A 1 238 ? -46.871 -30.958 58.817 1.00 60.08 ? 239 VAL A C 1 ATOM 1794 O O . VAL A 1 238 ? -46.712 -30.921 60.046 1.00 56.15 ? 239 VAL A O 1 ATOM 1795 C CB . VAL A 1 238 ? -44.711 -31.073 57.435 1.00 58.17 ? 239 VAL A CB 1 ATOM 1796 C CG1 . VAL A 1 238 ? -44.405 -32.197 58.440 1.00 48.63 ? 239 VAL A CG1 1 ATOM 1797 C CG2 . VAL A 1 238 ? -44.926 -31.597 56.045 1.00 56.37 ? 239 VAL A CG2 1 ATOM 1798 N N . GLY A 1 239 ? -47.887 -31.607 58.245 1.00 51.62 ? 240 GLY A N 1 ATOM 1799 C CA . GLY A 1 239 ? -48.894 -32.314 59.026 1.00 45.73 ? 240 GLY A CA 1 ATOM 1800 C C . GLY A 1 239 ? -48.402 -33.680 59.470 1.00 53.55 ? 240 GLY A C 1 ATOM 1801 O O . GLY A 1 239 ? -47.328 -34.103 59.070 1.00 55.71 ? 240 GLY A O 1 ATOM 1802 N N . MET A 1 240 ? -49.176 -34.375 60.297 1.00 55.76 ? 241 MET A N 1 ATOM 1803 C CA . MET A 1 240 ? -48.806 -35.723 60.729 1.00 57.43 ? 241 MET A CA 1 ATOM 1804 C C . MET A 1 240 ? -48.888 -36.718 59.572 1.00 57.56 ? 241 MET A C 1 ATOM 1805 O O . MET A 1 240 ? -48.018 -37.577 59.420 1.00 62.60 ? 241 MET A O 1 ATOM 1806 C CB . MET A 1 240 ? -49.678 -36.192 61.902 1.00 65.92 ? 241 MET A CB 1 ATOM 1807 C CG . MET A 1 240 ? -49.569 -35.331 63.149 1.00 69.09 ? 241 MET A CG 1 ATOM 1808 S SD . MET A 1 240 ? -50.343 -36.036 64.635 1.00 79.67 ? 241 MET A SD 1 ATOM 1809 C CE . MET A 1 240 ? -52.075 -35.767 64.265 1.00 65.78 ? 241 MET A CE 1 ATOM 1810 N N . GLY A 1 241 ? -49.933 -36.601 58.758 1.00 59.09 ? 242 GLY A N 1 ATOM 1811 C CA . GLY A 1 241 ? -50.036 -37.364 57.524 1.00 55.85 ? 242 GLY A CA 1 ATOM 1812 C C . GLY A 1 241 ? -48.795 -37.298 56.641 1.00 59.12 ? 242 GLY A C 1 ATOM 1813 O O . GLY A 1 241 ? -48.195 -38.339 56.344 1.00 57.61 ? 242 GLY A O 1 ATOM 1814 N N . GLU A 1 242 ? -48.397 -36.092 56.225 1.00 53.73 ? 243 GLU A N 1 ATOM 1815 C CA . GLU A 1 242 ? -47.221 -35.947 55.362 1.00 54.62 ? 243 GLU A CA 1 ATOM 1816 C C . GLU A 1 242 ? -45.935 -36.430 56.027 1.00 58.85 ? 243 GLU A C 1 ATOM 1817 O O . GLU A 1 242 ? -45.093 -37.059 55.394 1.00 59.32 ? 243 GLU A O 1 ATOM 1818 C CB . GLU A 1 242 ? -47.045 -34.501 54.893 1.00 53.00 ? 243 GLU A CB 1 ATOM 1819 C CG . GLU A 1 242 ? -47.422 -34.265 53.433 1.00 61.07 ? 243 GLU A CG 1 ATOM 1820 C CD . GLU A 1 242 ? -46.579 -35.074 52.450 1.00 62.19 ? 243 GLU A CD 1 ATOM 1821 O OE1 . GLU A 1 242 ? -47.045 -36.151 52.010 1.00 71.62 ? 243 GLU A OE1 1 ATOM 1822 O OE2 . GLU A 1 242 ? -45.458 -34.636 52.104 1.00 61.30 ? 243 GLU A OE2 1 ATOM 1823 N N . ALA A 1 243 ? -45.789 -36.147 57.315 1.00 59.66 ? 244 ALA A N 1 ATOM 1824 C CA . ALA A 1 243 ? -44.552 -36.450 58.008 1.00 50.48 ? 244 ALA A CA 1 ATOM 1825 C C . ALA A 1 243 ? -44.362 -37.948 58.153 1.00 57.69 ? 244 ALA A C 1 ATOM 1826 O O . ALA A 1 243 ? -43.229 -38.443 58.117 1.00 60.08 ? 244 ALA A O 1 ATOM 1827 C CB . ALA A 1 243 ? -44.528 -35.777 59.353 1.00 57.74 ? 244 ALA A CB 1 ATOM 1828 N N . ARG A 1 244 ? -45.470 -38.663 58.338 1.00 61.59 ? 245 ARG A N 1 ATOM 1829 C CA . ARG A 1 244 ? -45.438 -40.128 58.380 1.00 62.38 ? 245 ARG A CA 1 ATOM 1830 C C . ARG A 1 244 ? -45.139 -40.695 56.992 1.00 58.62 ? 245 ARG A C 1 ATOM 1831 O O . ARG A 1 244 ? -44.418 -41.681 56.866 1.00 56.71 ? 245 ARG A O 1 ATOM 1832 C CB . ARG A 1 244 ? -46.748 -40.708 58.920 1.00 52.23 ? 245 ARG A CB 1 ATOM 1833 C CG . ARG A 1 244 ? -46.809 -42.226 58.843 1.00 55.68 ? 245 ARG A CG 1 ATOM 1834 C CD . ARG A 1 244 ? -47.940 -42.827 59.680 1.00 50.63 ? 245 ARG A CD 1 ATOM 1835 N NE . ARG A 1 244 ? -47.730 -42.642 61.117 1.00 66.14 ? 245 ARG A NE 1 ATOM 1836 C CZ . ARG A 1 244 ? -47.066 -43.493 61.895 1.00 73.07 ? 245 ARG A CZ 1 ATOM 1837 N NH1 . ARG A 1 244 ? -46.540 -44.596 61.378 1.00 74.84 ? 245 ARG A NH1 1 ATOM 1838 N NH2 . ARG A 1 244 ? -46.927 -43.245 63.194 1.00 72.66 ? 245 ARG A NH2 1 ATOM 1839 N N A ARG A 1 245 ? -45.707 -40.076 55.955 0.51 55.26 ? 246 ARG A N 1 ATOM 1840 N N B ARG A 1 245 ? -45.683 -40.042 55.971 0.49 55.91 ? 246 ARG A N 1 ATOM 1841 C CA A ARG A 1 245 ? -45.461 -40.516 54.582 0.51 57.79 ? 246 ARG A CA 1 ATOM 1842 C CA B ARG A 1 245 ? -45.503 -40.447 54.584 0.49 58.38 ? 246 ARG A CA 1 ATOM 1843 C C A ARG A 1 245 ? -43.988 -40.347 54.239 0.51 59.15 ? 246 ARG A C 1 ATOM 1844 C C B ARG A 1 245 ? -44.047 -40.289 54.151 0.49 59.18 ? 246 ARG A C 1 ATOM 1845 O O A ARG A 1 245 ? -43.352 -41.273 53.736 0.51 62.03 ? 246 ARG A O 1 ATOM 1846 O O B ARG A 1 245 ? -43.485 -41.163 53.492 0.49 62.23 ? 246 ARG A O 1 ATOM 1847 C CB A ARG A 1 245 ? -46.327 -39.752 53.563 0.51 57.33 ? 246 ARG A CB 1 ATOM 1848 C CB B ARG A 1 245 ? -46.405 -39.592 53.693 0.49 57.41 ? 246 ARG A CB 1 ATOM 1849 C CG A ARG A 1 245 ? -46.296 -40.370 52.158 0.51 59.39 ? 246 ARG A CG 1 ATOM 1850 C CG B ARG A 1 245 ? -47.034 -40.324 52.539 0.49 57.91 ? 246 ARG A CG 1 ATOM 1851 C CD A ARG A 1 245 ? -46.908 -39.488 51.044 0.51 55.19 ? 246 ARG A CD 1 ATOM 1852 C CD B ARG A 1 245 ? -48.087 -39.457 51.862 0.49 57.39 ? 246 ARG A CD 1 ATOM 1853 N NE A ARG A 1 245 ? -46.118 -38.298 50.736 0.51 51.01 ? 246 ARG A NE 1 ATOM 1854 N NE B ARG A 1 245 ? -49.291 -39.330 52.676 0.49 53.12 ? 246 ARG A NE 1 ATOM 1855 C CZ A ARG A 1 245 ? -44.882 -38.317 50.243 0.51 56.13 ? 246 ARG A CZ 1 ATOM 1856 C CZ B ARG A 1 245 ? -49.815 -38.172 53.060 0.49 54.03 ? 246 ARG A CZ 1 ATOM 1857 N NH1 A ARG A 1 245 ? -44.274 -39.467 50.000 0.51 56.89 ? 246 ARG A NH1 1 ATOM 1858 N NH1 B ARG A 1 245 ? -49.244 -37.033 52.704 0.49 52.03 ? 246 ARG A NH1 1 ATOM 1859 N NH2 A ARG A 1 245 ? -44.245 -37.181 50.001 0.51 56.93 ? 246 ARG A NH2 1 ATOM 1860 N NH2 B ARG A 1 245 ? -50.915 -38.152 53.800 0.49 50.44 ? 246 ARG A NH2 1 ATOM 1861 N N . ARG A 1 246 ? -43.447 -39.165 54.527 1.00 59.03 ? 247 ARG A N 1 ATOM 1862 C CA . ARG A 1 246 ? -42.056 -38.858 54.186 1.00 58.80 ? 247 ARG A CA 1 ATOM 1863 C C . ARG A 1 246 ? -41.016 -39.749 54.876 1.00 56.95 ? 247 ARG A C 1 ATOM 1864 O O . ARG A 1 246 ? -40.032 -40.168 54.262 1.00 58.08 ? 247 ARG A O 1 ATOM 1865 C CB . ARG A 1 246 ? -41.756 -37.385 54.459 1.00 51.51 ? 247 ARG A CB 1 ATOM 1866 C CG . ARG A 1 246 ? -42.521 -36.446 53.547 1.00 53.39 ? 247 ARG A CG 1 ATOM 1867 C CD . ARG A 1 246 ? -41.962 -35.057 53.591 1.00 47.91 ? 247 ARG A CD 1 ATOM 1868 N NE . ARG A 1 246 ? -42.839 -34.099 52.945 1.00 48.08 ? 247 ARG A NE 1 ATOM 1869 C CZ . ARG A 1 246 ? -42.613 -32.792 52.919 1.00 54.89 ? 247 ARG A CZ 1 ATOM 1870 N NH1 . ARG A 1 246 ? -41.541 -32.302 53.526 1.00 54.58 ? 247 ARG A NH1 1 ATOM 1871 N NH2 . ARG A 1 246 ? -43.459 -31.975 52.298 1.00 52.42 ? 247 ARG A NH2 1 ATOM 1872 N N . ALA A 1 247 ? -41.248 -40.044 56.145 1.00 53.30 ? 248 ALA A N 1 ATOM 1873 C CA . ALA A 1 247 ? -40.321 -40.850 56.924 1.00 60.93 ? 248 ALA A CA 1 ATOM 1874 C C . ALA A 1 247 ? -40.410 -42.307 56.507 1.00 58.50 ? 248 ALA A C 1 ATOM 1875 O O . ALA A 1 247 ? -39.435 -43.049 56.581 1.00 60.80 ? 248 ALA A O 1 ATOM 1876 C CB . ALA A 1 247 ? -40.616 -40.708 58.422 1.00 55.23 ? 248 ALA A CB 1 ATOM 1877 N N . THR A 1 248 ? -41.601 -42.711 56.093 1.00 59.41 ? 249 THR A N 1 ATOM 1878 C CA . THR A 1 248 ? -41.840 -44.080 55.671 1.00 64.32 ? 249 THR A CA 1 ATOM 1879 C C . THR A 1 248 ? -41.245 -44.314 54.284 1.00 61.74 ? 249 THR A C 1 ATOM 1880 O O . THR A 1 248 ? -40.627 -45.356 54.050 1.00 61.95 ? 249 THR A O 1 ATOM 1881 C CB . THR A 1 248 ? -43.340 -44.415 55.699 1.00 65.81 ? 249 THR A CB 1 ATOM 1882 O OG1 . THR A 1 248 ? -43.787 -44.414 57.060 1.00 63.91 ? 249 THR A OG1 1 ATOM 1883 C CG2 . THR A 1 248 ? -43.601 -45.774 55.089 1.00 61.65 ? 249 THR A CG2 1 ATOM 1884 N N . GLN A 1 249 ? -41.410 -43.336 53.388 1.00 53.82 ? 250 GLN A N 1 ATOM 1885 C CA . GLN A 1 249 ? -40.704 -43.332 52.102 1.00 58.94 ? 250 GLN A CA 1 ATOM 1886 C C . GLN A 1 249 ? -39.197 -43.538 52.279 1.00 60.00 ? 250 GLN A C 1 ATOM 1887 O O . GLN A 1 249 ? -38.643 -44.500 51.748 1.00 66.22 ? 250 GLN A O 1 ATOM 1888 C CB . GLN A 1 249 ? -40.991 -42.050 51.298 1.00 58.09 ? 250 GLN A CB 1 ATOM 1889 C CG . GLN A 1 249 ? -40.266 -42.016 49.953 1.00 66.99 ? 250 GLN A CG 1 ATOM 1890 C CD . GLN A 1 249 ? -40.873 -41.048 48.924 1.00 76.22 ? 250 GLN A CD 1 ATOM 1891 O OE1 . GLN A 1 249 ? -41.615 -40.121 49.278 1.00 75.68 ? 250 GLN A OE1 1 ATOM 1892 N NE2 . GLN A 1 249 ? -40.544 -41.265 47.636 1.00 61.10 ? 250 GLN A NE2 1 ATOM 1893 N N . LEU A 1 250 ? -38.553 -42.647 53.038 1.00 60.62 ? 251 LEU A N 1 ATOM 1894 C CA . LEU A 1 250 ? -37.126 -42.766 53.412 1.00 61.96 ? 251 LEU A CA 1 ATOM 1895 C C . LEU A 1 250 ? -36.704 -44.139 53.945 1.00 60.78 ? 251 LEU A C 1 ATOM 1896 O O . LEU A 1 250 ? -35.615 -44.628 53.640 1.00 63.05 ? 251 LEU A O 1 ATOM 1897 C CB . LEU A 1 250 ? -36.735 -41.700 54.459 1.00 58.59 ? 251 LEU A CB 1 ATOM 1898 C CG . LEU A 1 250 ? -35.258 -41.632 54.885 1.00 52.37 ? 251 LEU A CG 1 ATOM 1899 C CD1 . LEU A 1 250 ? -34.392 -41.053 53.788 1.00 56.15 ? 251 LEU A CD1 1 ATOM 1900 C CD2 . LEU A 1 250 ? -35.081 -40.807 56.123 1.00 62.28 ? 251 LEU A CD2 1 ATOM 1901 N N . ALA A 1 251 ? -37.552 -44.746 54.766 1.00 61.85 ? 252 ALA A N 1 ATOM 1902 C CA . ALA A 1 251 ? -37.216 -46.029 55.361 1.00 64.46 ? 252 ALA A CA 1 ATOM 1903 C C . ALA A 1 251 ? -37.268 -47.118 54.294 1.00 69.09 ? 252 ALA A C 1 ATOM 1904 O O . ALA A 1 251 ? -36.565 -48.123 54.383 1.00 68.84 ? 252 ALA A O 1 ATOM 1905 C CB . ALA A 1 251 ? -38.154 -46.349 56.529 1.00 61.63 ? 252 ALA A CB 1 ATOM 1906 N N . HIS A 1 252 ? -38.101 -46.910 53.276 1.00 71.79 ? 253 HIS A N 1 ATOM 1907 C CA . HIS A 1 252 ? -38.185 -47.848 52.163 1.00 63.88 ? 253 HIS A CA 1 ATOM 1908 C C . HIS A 1 252 ? -36.924 -47.723 51.311 1.00 67.80 ? 253 HIS A C 1 ATOM 1909 O O . HIS A 1 252 ? -36.318 -48.733 50.940 1.00 66.32 ? 253 HIS A O 1 ATOM 1910 C CB . HIS A 1 252 ? -39.464 -47.618 51.355 1.00 58.85 ? 253 HIS A CB 1 ATOM 1911 C CG . HIS A 1 252 ? -39.528 -48.389 50.064 1.00 79.85 ? 253 HIS A CG 1 ATOM 1912 N ND1 . HIS A 1 252 ? -39.349 -47.797 48.831 1.00 73.79 ? 253 HIS A ND1 1 ATOM 1913 C CD2 . HIS A 1 252 ? -39.769 -49.701 49.821 1.00 76.54 ? 253 HIS A CD2 1 ATOM 1914 C CE1 . HIS A 1 252 ? -39.468 -48.712 47.882 1.00 81.34 ? 253 HIS A CE1 1 ATOM 1915 N NE2 . HIS A 1 252 ? -39.720 -49.873 48.457 1.00 78.59 ? 253 HIS A NE2 1 ATOM 1916 N N . LEU A 1 253 ? -36.512 -46.485 51.036 1.00 67.38 ? 254 LEU A N 1 ATOM 1917 C CA . LEU A 1 253 ? -35.298 -46.234 50.252 1.00 64.19 ? 254 LEU A CA 1 ATOM 1918 C C . LEU A 1 253 ? -34.051 -46.887 50.857 1.00 67.25 ? 254 LEU A C 1 ATOM 1919 O O . LEU A 1 253 ? -33.242 -47.463 50.134 1.00 67.45 ? 254 LEU A O 1 ATOM 1920 C CB . LEU A 1 253 ? -35.074 -44.735 50.051 1.00 51.82 ? 254 LEU A CB 1 ATOM 1921 C CG . LEU A 1 253 ? -36.091 -44.070 49.123 1.00 63.81 ? 254 LEU A CG 1 ATOM 1922 C CD1 . LEU A 1 253 ? -35.901 -42.566 49.086 1.00 57.34 ? 254 LEU A CD1 1 ATOM 1923 C CD2 . LEU A 1 253 ? -35.989 -44.653 47.717 1.00 60.09 ? 254 LEU A CD2 1 ATOM 1924 N N . VAL A 1 254 ? -33.904 -46.816 52.179 1.00 61.69 ? 255 VAL A N 1 ATOM 1925 C CA . VAL A 1 254 ? -32.717 -47.373 52.820 1.00 59.52 ? 255 VAL A CA 1 ATOM 1926 C C . VAL A 1 254 ? -32.949 -48.825 53.250 1.00 65.86 ? 255 VAL A C 1 ATOM 1927 O O . VAL A 1 254 ? -32.087 -49.453 53.881 1.00 60.34 ? 255 VAL A O 1 ATOM 1928 C CB . VAL A 1 254 ? -32.222 -46.493 54.003 1.00 62.20 ? 255 VAL A CB 1 ATOM 1929 C CG1 . VAL A 1 254 ? -31.886 -45.081 53.513 1.00 56.27 ? 255 VAL A CG1 1 ATOM 1930 C CG2 . VAL A 1 254 ? -33.254 -46.452 55.131 1.00 63.76 ? 255 VAL A CG2 1 ATOM 1931 N N . GLY A 1 255 ? -34.124 -49.344 52.893 1.00 68.19 ? 256 GLY A N 1 ATOM 1932 C CA . GLY A 1 255 ? -34.474 -50.739 53.112 1.00 69.16 ? 256 GLY A CA 1 ATOM 1933 C C . GLY A 1 255 ? -34.927 -51.100 54.518 1.00 75.49 ? 256 GLY A C 1 ATOM 1934 O O . GLY A 1 255 ? -34.292 -51.918 55.184 1.00 76.85 ? 256 GLY A O 1 ATOM 1935 N N . CYS A 1 256 ? -36.034 -50.519 54.971 1.00 74.57 ? 257 CYS A N 1 ATOM 1936 C CA . CYS A 1 256 ? -36.483 -50.767 56.340 1.00 84.75 ? 257 CYS A CA 1 ATOM 1937 C C . CYS A 1 256 ? -37.924 -51.230 56.448 1.00 90.54 ? 257 CYS A C 1 ATOM 1938 O O . CYS A 1 256 ? -38.848 -50.442 56.236 1.00 88.31 ? 257 CYS A O 1 ATOM 1939 C CB . CYS A 1 256 ? -36.248 -49.538 57.223 1.00 75.77 ? 257 CYS A CB 1 ATOM 1940 S SG . CYS A 1 256 ? -34.533 -49.404 57.766 1.00 76.54 ? 257 CYS A SG 1 ATOM 1941 N N . PRO A 1 257 ? -38.113 -52.521 56.765 1.00 100.26 ? 258 PRO A N 1 ATOM 1942 C CA . PRO A 1 257 ? -39.446 -53.074 57.020 1.00 103.60 ? 258 PRO A CA 1 ATOM 1943 C C . PRO A 1 257 ? -40.195 -52.281 58.096 1.00 97.90 ? 258 PRO A C 1 ATOM 1944 O O . PRO A 1 257 ? -40.843 -51.281 57.767 1.00 90.29 ? 258 PRO A O 1 ATOM 1945 C CB . PRO A 1 257 ? -39.135 -54.499 57.494 1.00 102.99 ? 258 PRO A CB 1 ATOM 1946 C CG . PRO A 1 257 ? -37.876 -54.861 56.750 1.00 94.97 ? 258 PRO A CG 1 ATOM 1947 C CD . PRO A 1 257 ? -37.078 -53.576 56.717 1.00 96.17 ? 258 PRO A CD 1 ATOM 1948 N N . ASN A 1 264 ? -45.010 -51.754 61.966 1.00 83.16 ? 265 ASN A N 1 ATOM 1949 C CA . ASN A 1 264 ? -44.611 -51.510 63.356 1.00 77.28 ? 265 ASN A CA 1 ATOM 1950 C C . ASN A 1 264 ? -43.585 -50.377 63.447 1.00 76.13 ? 265 ASN A C 1 ATOM 1951 O O . ASN A 1 264 ? -42.457 -50.500 62.944 1.00 68.27 ? 265 ASN A O 1 ATOM 1952 C CB . ASN A 1 264 ? -44.064 -52.797 63.990 1.00 83.67 ? 265 ASN A CB 1 ATOM 1953 C CG . ASN A 1 264 ? -44.017 -52.739 65.520 1.00 88.62 ? 265 ASN A CG 1 ATOM 1954 O OD1 . ASN A 1 264 ? -43.915 -51.667 66.116 1.00 88.64 ? 265 ASN A OD1 1 ATOM 1955 N ND2 . ASN A 1 264 ? -44.088 -53.906 66.157 1.00 93.58 ? 265 ASN A ND2 1 ATOM 1956 N N . ASP A 1 265 ? -43.988 -49.275 64.084 1.00 77.16 ? 266 ASP A N 1 ATOM 1957 C CA . ASP A 1 265 ? -43.142 -48.080 64.196 1.00 73.50 ? 266 ASP A CA 1 ATOM 1958 C C . ASP A 1 265 ? -41.846 -48.321 64.971 1.00 72.65 ? 266 ASP A C 1 ATOM 1959 O O . ASP A 1 265 ? -40.816 -47.714 64.685 1.00 74.66 ? 266 ASP A O 1 ATOM 1960 C CB . ASP A 1 265 ? -43.908 -46.908 64.814 1.00 57.54 ? 266 ASP A CB 1 ATOM 1961 C CG . ASP A 1 265 ? -44.917 -46.294 63.854 1.00 78.54 ? 266 ASP A CG 1 ATOM 1962 O OD1 . ASP A 1 265 ? -44.862 -46.611 62.645 1.00 85.53 ? 266 ASP A OD1 1 ATOM 1963 O OD2 . ASP A 1 265 ? -45.759 -45.481 64.298 1.00 82.82 ? 266 ASP A OD2 1 ATOM 1964 N N . THR A 1 266 ? -41.891 -49.219 65.941 1.00 69.31 ? 267 THR A N 1 ATOM 1965 C CA . THR A 1 266 ? -40.695 -49.539 66.702 1.00 73.62 ? 267 THR A CA 1 ATOM 1966 C C . THR A 1 266 ? -39.627 -50.227 65.839 1.00 71.59 ? 267 THR A C 1 ATOM 1967 O O . THR A 1 266 ? -38.470 -49.805 65.842 1.00 66.92 ? 267 THR A O 1 ATOM 1968 C CB . THR A 1 266 ? -41.037 -50.381 67.941 1.00 70.22 ? 267 THR A CB 1 ATOM 1969 O OG1 . THR A 1 266 ? -42.071 -49.725 68.682 1.00 68.51 ? 267 THR A OG1 1 ATOM 1970 C CG2 . THR A 1 266 ? -39.817 -50.557 68.817 1.00 49.47 ? 267 THR A CG2 1 ATOM 1971 N N . GLU A 1 267 ? -40.019 -51.276 65.110 1.00 75.64 ? 268 GLU A N 1 ATOM 1972 C CA . GLU A 1 267 ? -39.127 -51.961 64.163 1.00 75.85 ? 268 GLU A CA 1 ATOM 1973 C C . GLU A 1 267 ? -38.543 -51.015 63.112 1.00 70.29 ? 268 GLU A C 1 ATOM 1974 O O . GLU A 1 267 ? -37.370 -51.122 62.742 1.00 62.91 ? 268 GLU A O 1 ATOM 1975 C CB . GLU A 1 267 ? -39.869 -53.075 63.426 1.00 85.46 ? 268 GLU A CB 1 ATOM 1976 C CG . GLU A 1 267 ? -40.192 -54.309 64.244 1.00 91.60 ? 268 GLU A CG 1 ATOM 1977 C CD . GLU A 1 267 ? -41.045 -55.298 63.462 1.00 105.91 ? 268 GLU A CD 1 ATOM 1978 O OE1 . GLU A 1 267 ? -41.132 -55.159 62.216 1.00 105.97 ? 268 GLU A OE1 1 ATOM 1979 O OE2 . GLU A 1 267 ? -41.633 -56.206 64.092 1.00 113.01 ? 268 GLU A OE2 1 ATOM 1980 N N . LEU A 1 268 ? -39.375 -50.103 62.624 1.00 66.47 ? 269 LEU A N 1 ATOM 1981 C CA . LEU A 1 268 ? -38.949 -49.164 61.597 1.00 68.55 ? 269 LEU A CA 1 ATOM 1982 C C . LEU A 1 268 ? -37.812 -48.246 62.066 1.00 69.21 ? 269 LEU A C 1 ATOM 1983 O O . LEU A 1 268 ? -36.848 -48.017 61.331 1.00 68.04 ? 269 LEU A O 1 ATOM 1984 C CB . LEU A 1 268 ? -40.142 -48.340 61.111 1.00 69.90 ? 269 LEU A CB 1 ATOM 1985 C CG . LEU A 1 268 ? -39.972 -47.629 59.770 1.00 68.27 ? 269 LEU A CG 1 ATOM 1986 C CD1 . LEU A 1 268 ? -41.256 -47.679 58.984 1.00 69.28 ? 269 LEU A CD1 1 ATOM 1987 C CD2 . LEU A 1 268 ? -39.559 -46.191 59.986 1.00 69.79 ? 269 LEU A CD2 1 ATOM 1988 N N . VAL A 1 269 ? -37.920 -47.721 63.286 1.00 68.37 ? 270 VAL A N 1 ATOM 1989 C CA . VAL A 1 269 ? -36.916 -46.794 63.789 1.00 55.42 ? 270 VAL A CA 1 ATOM 1990 C C . VAL A 1 269 ? -35.707 -47.560 64.295 1.00 55.88 ? 270 VAL A C 1 ATOM 1991 O O . VAL A 1 269 ? -34.569 -47.119 64.143 1.00 59.58 ? 270 VAL A O 1 ATOM 1992 C CB . VAL A 1 269 ? -37.486 -45.867 64.882 1.00 62.72 ? 270 VAL A CB 1 ATOM 1993 C CG1 . VAL A 1 269 ? -36.466 -44.818 65.286 1.00 61.13 ? 270 VAL A CG1 1 ATOM 1994 C CG2 . VAL A 1 269 ? -38.729 -45.181 64.382 1.00 63.73 ? 270 VAL A CG2 1 ATOM 1995 N N . ALA A 1 270 ? -35.948 -48.723 64.882 1.00 57.38 ? 271 ALA A N 1 ATOM 1996 C CA . ALA A 1 270 ? -34.851 -49.580 65.311 1.00 58.40 ? 271 ALA A CA 1 ATOM 1997 C C . ALA A 1 270 ? -33.950 -49.882 64.110 1.00 65.81 ? 271 ALA A C 1 ATOM 1998 O O . ALA A 1 270 ? -32.725 -49.773 64.204 1.00 67.93 ? 271 ALA A O 1 ATOM 1999 C CB . ALA A 1 270 ? -35.382 -50.866 65.939 1.00 48.36 ? 271 ALA A CB 1 ATOM 2000 N N . CYS A 1 271 ? -34.576 -50.228 62.980 1.00 66.94 ? 272 CYS A N 1 ATOM 2001 C CA . CYS A 1 271 ? -33.880 -50.408 61.701 1.00 63.84 ? 272 CYS A CA 1 ATOM 2002 C C . CYS A 1 271 ? -33.163 -49.145 61.211 1.00 64.75 ? 272 CYS A C 1 ATOM 2003 O O . CYS A 1 271 ? -31.969 -49.192 60.893 1.00 67.02 ? 272 CYS A O 1 ATOM 2004 C CB . CYS A 1 271 ? -34.840 -50.925 60.621 1.00 67.11 ? 272 CYS A CB 1 ATOM 2005 S SG . CYS A 1 271 ? -34.114 -51.050 58.931 1.00 87.82 ? 272 CYS A SG 1 ATOM 2006 N N . LEU A 1 272 ? -33.885 -48.026 61.142 1.00 60.75 ? 273 LEU A N 1 ATOM 2007 C CA . LEU A 1 272 ? -33.274 -46.740 60.790 1.00 59.68 ? 273 LEU A CA 1 ATOM 2008 C C . LEU A 1 272 ? -32.022 -46.388 61.612 1.00 64.15 ? 273 LEU A C 1 ATOM 2009 O O . LEU A 1 272 ? -31.095 -45.771 61.096 1.00 62.59 ? 273 LEU A O 1 ATOM 2010 C CB . LEU A 1 272 ? -34.293 -45.613 60.924 1.00 60.10 ? 273 LEU A CB 1 ATOM 2011 C CG . LEU A 1 272 ? -35.226 -45.437 59.737 1.00 55.35 ? 273 LEU A CG 1 ATOM 2012 C CD1 . LEU A 1 272 ? -36.190 -44.291 59.973 1.00 53.39 ? 273 LEU A CD1 1 ATOM 2013 C CD2 . LEU A 1 272 ? -34.380 -45.177 58.517 1.00 69.30 ? 273 LEU A CD2 1 ATOM 2014 N N . ARG A 1 273 ? -31.996 -46.770 62.888 1.00 60.92 ? 274 ARG A N 1 ATOM 2015 C CA . ARG A 1 273 ? -30.895 -46.372 63.770 1.00 65.17 ? 274 ARG A CA 1 ATOM 2016 C C . ARG A 1 273 ? -29.586 -47.096 63.454 1.00 61.67 ? 274 ARG A C 1 ATOM 2017 O O . ARG A 1 273 ? -28.510 -46.648 63.849 1.00 61.59 ? 274 ARG A O 1 ATOM 2018 C CB . ARG A 1 273 ? -31.281 -46.535 65.249 1.00 60.93 ? 274 ARG A CB 1 ATOM 2019 C CG . ARG A 1 273 ? -32.292 -45.504 65.737 1.00 57.61 ? 274 ARG A CG 1 ATOM 2020 C CD . ARG A 1 273 ? -32.245 -45.360 67.239 1.00 63.62 ? 274 ARG A CD 1 ATOM 2021 N NE . ARG A 1 273 ? -33.372 -46.011 67.899 1.00 67.75 ? 274 ARG A NE 1 ATOM 2022 C CZ . ARG A 1 273 ? -34.378 -45.358 68.480 1.00 73.86 ? 274 ARG A CZ 1 ATOM 2023 N NH1 . ARG A 1 273 ? -34.418 -44.020 68.497 1.00 57.39 ? 274 ARG A NH1 1 ATOM 2024 N NH2 . ARG A 1 273 ? -35.351 -46.047 69.060 1.00 80.96 ? 274 ARG A NH2 1 ATOM 2025 N N . THR A 1 274 ? -29.688 -48.205 62.729 1.00 63.22 ? 275 THR A N 1 ATOM 2026 C CA . THR A 1 274 ? -28.516 -48.990 62.328 1.00 66.84 ? 275 THR A CA 1 ATOM 2027 C C . THR A 1 274 ? -27.808 -48.455 61.075 1.00 64.69 ? 275 THR A C 1 ATOM 2028 O O . THR A 1 274 ? -26.656 -48.801 60.826 1.00 68.11 ? 275 THR A O 1 ATOM 2029 C CB . THR A 1 274 ? -28.878 -50.466 62.058 1.00 66.31 ? 275 THR A CB 1 ATOM 2030 O OG1 . THR A 1 274 ? -29.708 -50.554 60.888 1.00 67.68 ? 275 THR A OG1 1 ATOM 2031 C CG2 . THR A 1 274 ? -29.591 -51.092 63.262 1.00 51.03 ? 275 THR A CG2 1 ATOM 2032 N N . ARG A 1 275 ? -28.497 -47.623 60.293 1.00 62.56 ? 276 ARG A N 1 ATOM 2033 C CA . ARG A 1 275 ? -27.941 -47.060 59.054 1.00 64.89 ? 276 ARG A CA 1 ATOM 2034 C C . ARG A 1 275 ? -26.946 -45.930 59.308 1.00 65.27 ? 276 ARG A C 1 ATOM 2035 O O . ARG A 1 275 ? -27.214 -45.043 60.122 1.00 65.77 ? 276 ARG A O 1 ATOM 2036 C CB . ARG A 1 275 ? -29.068 -46.543 58.145 1.00 60.67 ? 276 ARG A CB 1 ATOM 2037 C CG . ARG A 1 275 ? -30.005 -47.622 57.648 1.00 64.21 ? 276 ARG A CG 1 ATOM 2038 C CD . ARG A 1 275 ? -29.213 -48.758 57.022 1.00 67.08 ? 276 ARG A CD 1 ATOM 2039 N NE . ARG A 1 275 ? -30.065 -49.725 56.345 1.00 73.26 ? 276 ARG A NE 1 ATOM 2040 C CZ . ARG A 1 275 ? -30.485 -50.860 56.889 1.00 74.64 ? 276 ARG A CZ 1 ATOM 2041 N NH1 . ARG A 1 275 ? -30.138 -51.171 58.130 1.00 79.60 ? 276 ARG A NH1 1 ATOM 2042 N NH2 . ARG A 1 275 ? -31.254 -51.683 56.190 1.00 77.10 ? 276 ARG A NH2 1 ATOM 2043 N N . PRO A 1 276 ? -25.803 -45.947 58.597 1.00 69.31 ? 277 PRO A N 1 ATOM 2044 C CA . PRO A 1 276 ? -24.809 -44.879 58.760 1.00 66.04 ? 277 PRO A CA 1 ATOM 2045 C C . PRO A 1 276 ? -25.430 -43.558 58.383 1.00 62.64 ? 277 PRO A C 1 ATOM 2046 O O . PRO A 1 276 ? -26.293 -43.534 57.504 1.00 67.21 ? 277 PRO A O 1 ATOM 2047 C CB . PRO A 1 276 ? -23.715 -45.245 57.745 1.00 56.59 ? 277 PRO A CB 1 ATOM 2048 C CG . PRO A 1 276 ? -23.888 -46.708 57.506 1.00 57.67 ? 277 PRO A CG 1 ATOM 2049 C CD . PRO A 1 276 ? -25.377 -46.945 57.602 1.00 64.10 ? 277 PRO A CD 1 ATOM 2050 N N . ALA A 1 277 ? -25.003 -42.487 59.041 1.00 67.92 ? 278 ALA A N 1 ATOM 2051 C CA . ALA A 1 277 ? -25.579 -41.167 58.817 1.00 64.23 ? 278 ALA A CA 1 ATOM 2052 C C . ALA A 1 277 ? -25.634 -40.792 57.337 1.00 59.24 ? 278 ALA A C 1 ATOM 2053 O O . ALA A 1 277 ? -26.680 -40.346 56.859 1.00 53.15 ? 278 ALA A O 1 ATOM 2054 C CB . ALA A 1 277 ? -24.832 -40.110 59.615 1.00 59.65 ? 278 ALA A CB 1 ATOM 2055 N N . GLN A 1 278 ? -24.529 -40.998 56.614 1.00 66.11 ? 279 GLN A N 1 ATOM 2056 C CA . GLN A 1 278 ? -24.472 -40.638 55.184 1.00 63.17 ? 279 GLN A CA 1 ATOM 2057 C C . GLN A 1 278 ? -25.565 -41.298 54.320 1.00 60.80 ? 279 GLN A C 1 ATOM 2058 O O . GLN A 1 278 ? -26.193 -40.635 53.488 1.00 64.32 ? 279 GLN A O 1 ATOM 2059 C CB . GLN A 1 278 ? -23.083 -40.871 54.569 1.00 59.68 ? 279 GLN A CB 1 ATOM 2060 C CG . GLN A 1 278 ? -22.991 -40.291 53.142 1.00 73.90 ? 279 GLN A CG 1 ATOM 2061 C CD . GLN A 1 278 ? -21.599 -40.333 52.551 1.00 75.16 ? 279 GLN A CD 1 ATOM 2062 O OE1 . GLN A 1 278 ? -21.044 -41.406 52.319 1.00 87.63 ? 279 GLN A OE1 1 ATOM 2063 N NE2 . GLN A 1 278 ? -21.027 -39.160 52.297 1.00 68.54 ? 279 GLN A NE2 1 ATOM 2064 N N . VAL A 1 279 ? -25.796 -42.590 54.525 1.00 55.83 ? 280 VAL A N 1 ATOM 2065 C CA . VAL A 1 279 ? -26.894 -43.283 53.854 1.00 57.53 ? 280 VAL A CA 1 ATOM 2066 C C . VAL A 1 279 ? -28.255 -42.583 54.048 1.00 59.98 ? 280 VAL A C 1 ATOM 2067 O O . VAL A 1 279 ? -29.106 -42.622 53.161 1.00 61.43 ? 280 VAL A O 1 ATOM 2068 C CB . VAL A 1 279 ? -26.973 -44.765 54.305 1.00 58.22 ? 280 VAL A CB 1 ATOM 2069 C CG1 . VAL A 1 279 ? -28.277 -45.406 53.882 1.00 51.52 ? 280 VAL A CG1 1 ATOM 2070 C CG2 . VAL A 1 279 ? -25.807 -45.546 53.750 1.00 53.58 ? 280 VAL A CG2 1 ATOM 2071 N N . LEU A 1 280 ? -28.464 -41.934 55.195 1.00 63.71 ? 281 LEU A N 1 ATOM 2072 C CA . LEU A 1 280 ? -29.723 -41.216 55.428 1.00 59.35 ? 281 LEU A CA 1 ATOM 2073 C C . LEU A 1 280 ? -29.775 -39.883 54.687 1.00 57.83 ? 281 LEU A C 1 ATOM 2074 O O . LEU A 1 280 ? -30.806 -39.513 54.114 1.00 59.36 ? 281 LEU A O 1 ATOM 2075 C CB . LEU A 1 280 ? -29.989 -41.010 56.922 1.00 54.08 ? 281 LEU A CB 1 ATOM 2076 C CG . LEU A 1 280 ? -30.231 -42.274 57.760 1.00 57.97 ? 281 LEU A CG 1 ATOM 2077 C CD1 . LEU A 1 280 ? -30.731 -41.925 59.170 1.00 47.45 ? 281 LEU A CD1 1 ATOM 2078 C CD2 . LEU A 1 280 ? -31.187 -43.238 57.067 1.00 49.27 ? 281 LEU A CD2 1 ATOM 2079 N N . VAL A 1 281 ? -28.661 -39.164 54.697 1.00 55.30 ? 282 VAL A N 1 ATOM 2080 C CA . VAL A 1 281 ? -28.572 -37.899 53.974 1.00 60.21 ? 282 VAL A CA 1 ATOM 2081 C C . VAL A 1 281 ? -28.648 -38.117 52.446 1.00 61.88 ? 282 VAL A C 1 ATOM 2082 O O . VAL A 1 281 ? -29.287 -37.324 51.740 1.00 61.42 ? 282 VAL A O 1 ATOM 2083 C CB . VAL A 1 281 ? -27.318 -37.092 54.388 1.00 62.90 ? 282 VAL A CB 1 ATOM 2084 C CG1 . VAL A 1 281 ? -27.254 -35.775 53.657 1.00 61.24 ? 282 VAL A CG1 1 ATOM 2085 C CG2 . VAL A 1 281 ? -27.323 -36.846 55.900 1.00 54.67 ? 282 VAL A CG2 1 ATOM 2086 N N . ASN A 1 282 ? -28.035 -39.198 51.950 1.00 60.63 ? 283 ASN A N 1 ATOM 2087 C CA . ASN A 1 282 ? -28.133 -39.578 50.531 1.00 58.58 ? 283 ASN A CA 1 ATOM 2088 C C . ASN A 1 282 ? -29.561 -39.559 50.030 1.00 59.47 ? 283 ASN A C 1 ATOM 2089 O O . ASN A 1 282 ? -29.823 -39.137 48.908 1.00 58.01 ? 283 ASN A O 1 ATOM 2090 C CB . ASN A 1 282 ? -27.536 -40.967 50.261 1.00 55.38 ? 283 ASN A CB 1 ATOM 2091 C CG . ASN A 1 282 ? -26.019 -40.933 50.087 1.00 62.12 ? 283 ASN A CG 1 ATOM 2092 O OD1 . ASN A 1 282 ? -25.426 -39.866 49.900 1.00 64.88 ? 283 ASN A OD1 1 ATOM 2093 N ND2 . ASN A 1 282 ? -25.389 -42.106 50.129 1.00 55.00 ? 283 ASN A ND2 1 ATOM 2094 N N . HIS A 1 283 ? -30.490 -39.980 50.884 1.00 56.42 ? 284 HIS A N 1 ATOM 2095 C CA . HIS A 1 283 ? -31.881 -40.157 50.468 1.00 55.06 ? 284 HIS A CA 1 ATOM 2096 C C . HIS A 1 283 ? -32.883 -39.068 50.883 1.00 54.43 ? 284 HIS A C 1 ATOM 2097 O O . HIS A 1 283 ? -34.053 -39.128 50.509 1.00 52.70 ? 284 HIS A O 1 ATOM 2098 C CB . HIS A 1 283 ? -32.351 -41.552 50.868 1.00 54.66 ? 284 HIS A CB 1 ATOM 2099 C CG . HIS A 1 283 ? -31.555 -42.646 50.221 1.00 63.23 ? 284 HIS A CG 1 ATOM 2100 N ND1 . HIS A 1 283 ? -30.369 -43.109 50.744 1.00 60.22 ? 284 HIS A ND1 1 ATOM 2101 C CD2 . HIS A 1 283 ? -31.753 -43.330 49.066 1.00 57.63 ? 284 HIS A CD2 1 ATOM 2102 C CE1 . HIS A 1 283 ? -29.879 -44.050 49.953 1.00 61.57 ? 284 HIS A CE1 1 ATOM 2103 N NE2 . HIS A 1 283 ? -30.699 -44.202 48.931 1.00 57.99 ? 284 HIS A NE2 1 ATOM 2104 N N . GLU A 1 284 ? -32.406 -38.062 51.613 1.00 60.68 ? 285 GLU A N 1 ATOM 2105 C CA . GLU A 1 284 ? -33.246 -36.988 52.143 1.00 57.05 ? 285 GLU A CA 1 ATOM 2106 C C . GLU A 1 284 ? -34.067 -36.256 51.077 1.00 53.33 ? 285 GLU A C 1 ATOM 2107 O O . GLU A 1 284 ? -35.265 -36.009 51.249 1.00 50.31 ? 285 GLU A O 1 ATOM 2108 C CB . GLU A 1 284 ? -32.391 -35.982 52.940 1.00 61.24 ? 285 GLU A CB 1 ATOM 2109 C CG . GLU A 1 284 ? -33.030 -34.589 53.097 1.00 67.71 ? 285 GLU A CG 1 ATOM 2110 C CD . GLU A 1 284 ? -32.312 -33.670 54.104 1.00 73.29 ? 285 GLU A CD 1 ATOM 2111 O OE1 . GLU A 1 284 ? -31.102 -33.871 54.368 1.00 68.49 ? 285 GLU A OE1 1 ATOM 2112 O OE2 . GLU A 1 284 ? -32.976 -32.741 54.633 1.00 63.23 ? 285 GLU A OE2 1 ATOM 2113 N N . TRP A 1 285 ? -33.432 -35.900 49.971 1.00 59.66 ? 286 TRP A N 1 ATOM 2114 C CA . TRP A 1 285 ? -34.121 -35.080 48.984 1.00 56.04 ? 286 TRP A CA 1 ATOM 2115 C C . TRP A 1 285 ? -35.178 -35.819 48.133 1.00 53.25 ? 286 TRP A C 1 ATOM 2116 O O . TRP A 1 285 ? -36.068 -35.183 47.574 1.00 54.24 ? 286 TRP A O 1 ATOM 2117 C CB . TRP A 1 285 ? -33.113 -34.341 48.126 1.00 52.57 ? 286 TRP A CB 1 ATOM 2118 C CG . TRP A 1 285 ? -32.410 -33.248 48.860 1.00 53.06 ? 286 TRP A CG 1 ATOM 2119 C CD1 . TRP A 1 285 ? -31.121 -33.262 49.326 1.00 54.57 ? 286 TRP A CD1 1 ATOM 2120 C CD2 . TRP A 1 285 ? -32.945 -31.962 49.200 1.00 51.25 ? 286 TRP A CD2 1 ATOM 2121 N NE1 . TRP A 1 285 ? -30.823 -32.063 49.932 1.00 54.76 ? 286 TRP A NE1 1 ATOM 2122 C CE2 . TRP A 1 285 ? -31.925 -31.249 49.872 1.00 55.57 ? 286 TRP A CE2 1 ATOM 2123 C CE3 . TRP A 1 285 ? -34.188 -31.346 49.006 1.00 45.15 ? 286 TRP A CE3 1 ATOM 2124 C CZ2 . TRP A 1 285 ? -32.113 -29.952 50.357 1.00 49.99 ? 286 TRP A CZ2 1 ATOM 2125 C CZ3 . TRP A 1 285 ? -34.372 -30.055 49.476 1.00 44.41 ? 286 TRP A CZ3 1 ATOM 2126 C CH2 . TRP A 1 285 ? -33.333 -29.368 50.138 1.00 46.66 ? 286 TRP A CH2 1 ATOM 2127 N N . HIS A 1 286 ? -35.094 -37.149 48.079 1.00 48.43 ? 287 HIS A N 1 ATOM 2128 C CA . HIS A 1 286 ? -36.062 -37.981 47.362 1.00 52.69 ? 287 HIS A CA 1 ATOM 2129 C C . HIS A 1 286 ? -37.494 -37.857 47.877 1.00 58.51 ? 287 HIS A C 1 ATOM 2130 O O . HIS A 1 286 ? -38.435 -38.052 47.110 1.00 61.91 ? 287 HIS A O 1 ATOM 2131 C CB . HIS A 1 286 ? -35.719 -39.474 47.463 1.00 55.40 ? 287 HIS A CB 1 ATOM 2132 C CG . HIS A 1 286 ? -34.357 -39.848 46.965 1.00 60.34 ? 287 HIS A CG 1 ATOM 2133 N ND1 . HIS A 1 286 ? -33.200 -39.249 47.415 1.00 66.16 ? 287 HIS A ND1 1 ATOM 2134 C CD2 . HIS A 1 286 ? -33.966 -40.808 46.093 1.00 65.28 ? 287 HIS A CD2 1 ATOM 2135 C CE1 . HIS A 1 286 ? -32.158 -39.805 46.823 1.00 66.92 ? 287 HIS A CE1 1 ATOM 2136 N NE2 . HIS A 1 286 ? -32.596 -40.754 46.014 1.00 67.03 ? 287 HIS A NE2 1 ATOM 2137 N N . VAL A 1 287 ? -37.667 -37.584 49.172 1.00 55.25 ? 288 VAL A N 1 ATOM 2138 C CA . VAL A 1 287 ? -38.982 -37.743 49.803 1.00 50.56 ? 288 VAL A CA 1 ATOM 2139 C C . VAL A 1 287 ? -39.899 -36.529 49.637 1.00 53.04 ? 288 VAL A C 1 ATOM 2140 O O . VAL A 1 287 ? -41.094 -36.590 49.976 1.00 53.18 ? 288 VAL A O 1 ATOM 2141 C CB . VAL A 1 287 ? -38.883 -38.162 51.298 1.00 56.03 ? 288 VAL A CB 1 ATOM 2142 C CG1 . VAL A 1 287 ? -37.935 -39.345 51.460 1.00 51.89 ? 288 VAL A CG1 1 ATOM 2143 C CG2 . VAL A 1 287 ? -38.450 -36.984 52.173 1.00 52.01 ? 288 VAL A CG2 1 ATOM 2144 N N . LEU A 1 288 ? -39.342 -35.442 49.108 1.00 46.81 ? 289 LEU A N 1 ATOM 2145 C CA . LEU A 1 288 ? -40.130 -34.259 48.757 1.00 56.15 ? 289 LEU A CA 1 ATOM 2146 C C . LEU A 1 288 ? -41.231 -34.598 47.753 1.00 70.65 ? 289 LEU A C 1 ATOM 2147 O O . LEU A 1 288 ? -40.947 -35.133 46.672 1.00 70.08 ? 289 LEU A O 1 ATOM 2148 C CB . LEU A 1 288 ? -39.238 -33.178 48.153 1.00 55.90 ? 289 LEU A CB 1 ATOM 2149 C CG . LEU A 1 288 ? -38.727 -32.092 49.088 1.00 58.71 ? 289 LEU A CG 1 ATOM 2150 C CD1 . LEU A 1 288 ? -37.943 -31.088 48.295 1.00 58.33 ? 289 LEU A CD1 1 ATOM 2151 C CD2 . LEU A 1 288 ? -39.881 -31.424 49.806 1.00 59.20 ? 289 LEU A CD2 1 ATOM 2152 N N . PRO A 1 289 ? -42.493 -34.277 48.102 1.00 72.92 ? 290 PRO A N 1 ATOM 2153 C CA . PRO A 1 289 ? -43.675 -34.578 47.287 1.00 70.31 ? 290 PRO A CA 1 ATOM 2154 C C . PRO A 1 289 ? -43.609 -33.996 45.872 1.00 78.75 ? 290 PRO A C 1 ATOM 2155 O O . PRO A 1 289 ? -43.451 -34.753 44.913 1.00 89.07 ? 290 PRO A O 1 ATOM 2156 C CB . PRO A 1 289 ? -44.817 -33.934 48.081 1.00 71.07 ? 290 PRO A CB 1 ATOM 2157 C CG . PRO A 1 289 ? -44.158 -32.923 48.947 1.00 67.47 ? 290 PRO A CG 1 ATOM 2158 C CD . PRO A 1 289 ? -42.860 -33.545 49.322 1.00 68.01 ? 290 PRO A CD 1 ATOM 2159 N N . GLN A 1 290 ? -43.723 -32.685 45.720 1.00 71.32 ? 291 GLN A N 1 ATOM 2160 C CA . GLN A 1 290 ? -43.809 -32.160 44.361 1.00 91.77 ? 291 GLN A CA 1 ATOM 2161 C C . GLN A 1 290 ? -42.602 -31.365 43.872 1.00 89.24 ? 291 GLN A C 1 ATOM 2162 O O . GLN A 1 290 ? -41.538 -31.336 44.516 1.00 83.28 ? 291 GLN A O 1 ATOM 2163 C CB . GLN A 1 290 ? -45.091 -31.344 44.170 1.00 98.60 ? 291 GLN A CB 1 ATOM 2164 C CG . GLN A 1 290 ? -46.290 -32.178 43.736 1.00 99.63 ? 291 GLN A CG 1 ATOM 2165 C CD . GLN A 1 290 ? -47.554 -31.351 43.610 1.00 101.50 ? 291 GLN A CD 1 ATOM 2166 O OE1 . GLN A 1 290 ? -47.500 -30.118 43.506 1.00 97.72 ? 291 GLN A OE1 1 ATOM 2167 N NE2 . GLN A 1 290 ? -48.703 -32.021 43.632 1.00 99.35 ? 291 GLN A NE2 1 ATOM 2168 N N . GLU A 1 291 ? -42.789 -30.753 42.704 1.00 65.50 ? 292 GLU A N 1 ATOM 2169 C CA . GLU A 1 291 ? -41.842 -29.804 42.151 1.00 67.97 ? 292 GLU A CA 1 ATOM 2170 C C . GLU A 1 291 ? -42.107 -28.419 42.752 1.00 67.48 ? 292 GLU A C 1 ATOM 2171 O O . GLU A 1 291 ? -43.246 -27.933 42.780 1.00 73.23 ? 292 GLU A O 1 ATOM 2172 C CB . GLU A 1 291 ? -41.942 -29.783 40.626 1.00 69.42 ? 292 GLU A CB 1 ATOM 2173 C CG . GLU A 1 291 ? -42.105 -31.185 40.014 1.00 79.12 ? 292 GLU A CG 1 ATOM 2174 C CD . GLU A 1 291 ? -42.089 -31.197 38.476 1.00 89.41 ? 292 GLU A CD 1 ATOM 2175 O OE1 . GLU A 1 291 ? -41.675 -30.188 37.849 1.00 82.83 ? 292 GLU A OE1 1 ATOM 2176 O OE2 . GLU A 1 291 ? -42.487 -32.230 37.891 1.00 93.17 ? 292 GLU A OE2 1 ATOM 2177 N N . SER A 1 292 ? -41.033 -27.796 43.224 1.00 67.68 ? 293 SER A N 1 ATOM 2178 C CA . SER A 1 292 ? -41.100 -26.652 44.126 1.00 63.34 ? 293 SER A CA 1 ATOM 2179 C C . SER A 1 292 ? -39.707 -26.095 44.342 1.00 60.63 ? 293 SER A C 1 ATOM 2180 O O . SER A 1 292 ? -38.725 -26.820 44.254 1.00 68.39 ? 293 SER A O 1 ATOM 2181 C CB . SER A 1 292 ? -41.628 -27.103 45.493 1.00 71.34 ? 293 SER A CB 1 ATOM 2182 O OG . SER A 1 292 ? -40.760 -28.052 46.118 1.00 62.01 ? 293 SER A OG 1 ATOM 2183 N N . VAL A 1 293 ? -39.615 -24.803 44.611 1.00 59.68 ? 294 VAL A N 1 ATOM 2184 C CA . VAL A 1 293 ? -38.437 -24.272 45.292 1.00 59.73 ? 294 VAL A CA 1 ATOM 2185 C C . VAL A 1 293 ? -38.879 -23.809 46.683 1.00 57.74 ? 294 VAL A C 1 ATOM 2186 O O . VAL A 1 293 ? -40.088 -23.617 46.908 1.00 51.91 ? 294 VAL A O 1 ATOM 2187 C CB . VAL A 1 293 ? -37.782 -23.130 44.508 1.00 59.47 ? 294 VAL A CB 1 ATOM 2188 C CG1 . VAL A 1 293 ? -37.123 -23.684 43.264 1.00 67.97 ? 294 VAL A CG1 1 ATOM 2189 C CG2 . VAL A 1 293 ? -38.812 -22.076 44.135 1.00 60.78 ? 294 VAL A CG2 1 ATOM 2190 N N . PHE A 1 294 ? -37.926 -23.658 47.610 1.00 56.38 ? 295 PHE A N 1 ATOM 2191 C CA . PHE A 1 294 ? -38.241 -23.192 48.964 1.00 40.83 ? 295 PHE A CA 1 ATOM 2192 C C . PHE A 1 294 ? -39.121 -24.248 49.659 1.00 48.60 ? 295 PHE A C 1 ATOM 2193 O O . PHE A 1 294 ? -40.192 -23.944 50.187 1.00 46.27 ? 295 PHE A O 1 ATOM 2194 C CB . PHE A 1 294 ? -38.963 -21.836 48.884 1.00 45.20 ? 295 PHE A CB 1 ATOM 2195 C CG . PHE A 1 294 ? -38.638 -20.887 49.993 1.00 55.16 ? 295 PHE A CG 1 ATOM 2196 C CD1 . PHE A 1 294 ? -38.479 -21.337 51.307 1.00 55.72 ? 295 PHE A CD1 1 ATOM 2197 C CD2 . PHE A 1 294 ? -38.497 -19.534 49.728 1.00 53.09 ? 295 PHE A CD2 1 ATOM 2198 C CE1 . PHE A 1 294 ? -38.190 -20.456 52.331 1.00 50.15 ? 295 PHE A CE1 1 ATOM 2199 C CE2 . PHE A 1 294 ? -38.195 -18.646 50.754 1.00 60.17 ? 295 PHE A CE2 1 ATOM 2200 C CZ . PHE A 1 294 ? -38.046 -19.109 52.057 1.00 52.49 ? 295 PHE A CZ 1 ATOM 2201 N N . ARG A 1 295 ? -38.680 -25.504 49.603 1.00 54.81 ? 296 ARG A N 1 ATOM 2202 C CA . ARG A 1 295 ? -39.346 -26.616 50.271 1.00 45.96 ? 296 ARG A CA 1 ATOM 2203 C C . ARG A 1 295 ? -38.289 -27.606 50.691 1.00 49.86 ? 296 ARG A C 1 ATOM 2204 O O . ARG A 1 295 ? -37.331 -27.842 49.963 1.00 51.39 ? 296 ARG A O 1 ATOM 2205 C CB . ARG A 1 295 ? -40.353 -27.321 49.368 1.00 41.53 ? 296 ARG A CB 1 ATOM 2206 C CG . ARG A 1 295 ? -41.583 -26.510 49.032 1.00 49.98 ? 296 ARG A CG 1 ATOM 2207 C CD . ARG A 1 295 ? -42.409 -26.178 50.259 1.00 44.83 ? 296 ARG A CD 1 ATOM 2208 N NE . ARG A 1 295 ? -43.654 -25.500 49.899 1.00 48.37 ? 296 ARG A NE 1 ATOM 2209 C CZ . ARG A 1 295 ? -43.772 -24.190 49.712 1.00 45.76 ? 296 ARG A CZ 1 ATOM 2210 N NH1 . ARG A 1 295 ? -42.718 -23.395 49.864 1.00 40.61 ? 296 ARG A NH1 1 ATOM 2211 N NH2 . ARG A 1 295 ? -44.950 -23.671 49.391 1.00 44.14 ? 296 ARG A NH2 1 ATOM 2212 N N . PHE A 1 296 ? -38.469 -28.193 51.873 1.00 52.64 ? 297 PHE A N 1 ATOM 2213 C CA . PHE A 1 296 ? -37.433 -29.006 52.477 1.00 43.55 ? 297 PHE A CA 1 ATOM 2214 C C . PHE A 1 296 ? -38.072 -30.257 53.012 1.00 43.89 ? 297 PHE A C 1 ATOM 2215 O O . PHE A 1 296 ? -39.239 -30.240 53.386 1.00 54.81 ? 297 PHE A O 1 ATOM 2216 C CB . PHE A 1 296 ? -36.737 -28.191 53.569 1.00 45.32 ? 297 PHE A CB 1 ATOM 2217 C CG . PHE A 1 296 ? -36.540 -26.752 53.195 1.00 42.83 ? 297 PHE A CG 1 ATOM 2218 C CD1 . PHE A 1 296 ? -35.571 -26.390 52.264 1.00 49.55 ? 297 PHE A CD1 1 ATOM 2219 C CD2 . PHE A 1 296 ? -37.359 -25.767 53.714 1.00 43.45 ? 297 PHE A CD2 1 ATOM 2220 C CE1 . PHE A 1 296 ? -35.404 -25.062 51.882 1.00 44.08 ? 297 PHE A CE1 1 ATOM 2221 C CE2 . PHE A 1 296 ? -37.204 -24.438 53.339 1.00 42.18 ? 297 PHE A CE2 1 ATOM 2222 C CZ . PHE A 1 296 ? -36.224 -24.084 52.434 1.00 49.68 ? 297 PHE A CZ 1 ATOM 2223 N N . SER A 1 297 ? -37.316 -31.344 53.040 1.00 42.47 ? 298 SER A N 1 ATOM 2224 C CA . SER A 1 297 ? -37.858 -32.646 53.419 1.00 50.15 ? 298 SER A CA 1 ATOM 2225 C C . SER A 1 297 ? -38.333 -32.811 54.883 1.00 57.14 ? 298 SER A C 1 ATOM 2226 O O . SER A 1 297 ? -39.474 -33.217 55.142 1.00 53.88 ? 298 SER A O 1 ATOM 2227 C CB . SER A 1 297 ? -36.855 -33.741 53.081 1.00 54.34 ? 298 SER A CB 1 ATOM 2228 O OG . SER A 1 297 ? -36.780 -33.934 51.686 1.00 49.65 ? 298 SER A OG 1 ATOM 2229 N N . PHE A 1 298 ? -37.464 -32.546 55.847 1.00 53.33 ? 299 PHE A N 1 ATOM 2230 C CA . PHE A 1 298 ? -37.877 -32.751 57.236 1.00 47.20 ? 299 PHE A CA 1 ATOM 2231 C C . PHE A 1 298 ? -37.926 -31.445 58.010 1.00 48.88 ? 299 PHE A C 1 ATOM 2232 O O . PHE A 1 298 ? -36.899 -30.824 58.276 1.00 48.15 ? 299 PHE A O 1 ATOM 2233 C CB . PHE A 1 298 ? -36.998 -33.792 57.919 1.00 47.98 ? 299 PHE A CB 1 ATOM 2234 C CG . PHE A 1 298 ? -37.006 -35.117 57.224 1.00 53.63 ? 299 PHE A CG 1 ATOM 2235 C CD1 . PHE A 1 298 ? -38.046 -36.014 57.423 1.00 53.47 ? 299 PHE A CD1 1 ATOM 2236 C CD2 . PHE A 1 298 ? -35.993 -35.454 56.336 1.00 58.44 ? 299 PHE A CD2 1 ATOM 2237 C CE1 . PHE A 1 298 ? -38.070 -37.239 56.755 1.00 52.35 ? 299 PHE A CE1 1 ATOM 2238 C CE2 . PHE A 1 298 ? -36.008 -36.673 55.673 1.00 56.45 ? 299 PHE A CE2 1 ATOM 2239 C CZ . PHE A 1 298 ? -37.050 -37.568 55.889 1.00 52.39 ? 299 PHE A CZ 1 ATOM 2240 N N . VAL A 1 299 ? -39.142 -31.023 58.335 1.00 47.07 ? 300 VAL A N 1 ATOM 2241 C CA . VAL A 1 299 ? -39.371 -29.750 58.998 1.00 48.66 ? 300 VAL A CA 1 ATOM 2242 C C . VAL A 1 299 ? -40.245 -29.989 60.244 1.00 47.68 ? 300 VAL A C 1 ATOM 2243 O O . VAL A 1 299 ? -40.679 -31.107 60.477 1.00 47.87 ? 300 VAL A O 1 ATOM 2244 C CB . VAL A 1 299 ? -39.993 -28.719 58.011 1.00 47.42 ? 300 VAL A CB 1 ATOM 2245 C CG1 . VAL A 1 299 ? -38.972 -28.313 56.985 1.00 45.81 ? 300 VAL A CG1 1 ATOM 2246 C CG2 . VAL A 1 299 ? -41.250 -29.270 57.353 1.00 46.06 ? 300 VAL A CG2 1 ATOM 2247 N N . PRO A 1 300 ? -40.466 -28.958 61.071 1.00 50.43 ? 301 PRO A N 1 ATOM 2248 C CA . PRO A 1 300 ? -41.299 -29.203 62.253 1.00 49.84 ? 301 PRO A CA 1 ATOM 2249 C C . PRO A 1 300 ? -42.705 -29.732 61.942 1.00 49.67 ? 301 PRO A C 1 ATOM 2250 O O . PRO A 1 300 ? -43.364 -29.191 61.067 1.00 55.04 ? 301 PRO A O 1 ATOM 2251 C CB . PRO A 1 300 ? -41.390 -27.820 62.888 1.00 46.81 ? 301 PRO A CB 1 ATOM 2252 C CG . PRO A 1 300 ? -40.097 -27.201 62.561 1.00 51.56 ? 301 PRO A CG 1 ATOM 2253 C CD . PRO A 1 300 ? -39.769 -27.662 61.166 1.00 48.48 ? 301 PRO A CD 1 ATOM 2254 N N . VAL A 1 301 ? -43.139 -30.767 62.662 1.00 44.71 ? 302 VAL A N 1 ATOM 2255 C CA . VAL A 1 301 ? -44.468 -31.354 62.501 1.00 46.68 ? 302 VAL A CA 1 ATOM 2256 C C . VAL A 1 301 ? -45.494 -30.846 63.528 1.00 52.01 ? 302 VAL A C 1 ATOM 2257 O O . VAL A 1 301 ? -45.197 -30.728 64.706 1.00 57.72 ? 302 VAL A O 1 ATOM 2258 C CB . VAL A 1 301 ? -44.401 -32.916 62.533 1.00 47.15 ? 302 VAL A CB 1 ATOM 2259 C CG1 . VAL A 1 301 ? -43.777 -33.408 63.822 1.00 55.11 ? 302 VAL A CG1 1 ATOM 2260 C CG2 . VAL A 1 301 ? -45.775 -33.524 62.369 1.00 53.81 ? 302 VAL A CG2 1 ATOM 2261 N N . VAL A 1 302 ? -46.696 -30.534 63.056 1.00 52.62 ? 303 VAL A N 1 ATOM 2262 C CA . VAL A 1 302 ? -47.845 -30.267 63.910 1.00 51.17 ? 303 VAL A CA 1 ATOM 2263 C C . VAL A 1 302 ? -48.452 -31.590 64.409 1.00 62.49 ? 303 VAL A C 1 ATOM 2264 O O . VAL A 1 302 ? -49.211 -32.248 63.688 1.00 67.30 ? 303 VAL A O 1 ATOM 2265 C CB . VAL A 1 302 ? -48.924 -29.465 63.155 1.00 50.11 ? 303 VAL A CB 1 ATOM 2266 C CG1 . VAL A 1 302 ? -50.191 -29.342 63.988 1.00 42.13 ? 303 VAL A CG1 1 ATOM 2267 C CG2 . VAL A 1 302 ? -48.394 -28.094 62.747 1.00 47.18 ? 303 VAL A CG2 1 ATOM 2268 N N . ASP A 1 303 ? -48.123 -31.946 65.652 1.00 63.45 ? 304 ASP A N 1 ATOM 2269 C CA . ASP A 1 303 ? -48.387 -33.264 66.236 1.00 59.54 ? 304 ASP A CA 1 ATOM 2270 C C . ASP A 1 303 ? -49.298 -33.223 67.480 1.00 67.97 ? 304 ASP A C 1 ATOM 2271 O O . ASP A 1 303 ? -49.711 -34.267 67.987 1.00 66.97 ? 304 ASP A O 1 ATOM 2272 C CB . ASP A 1 303 ? -47.049 -33.925 66.629 1.00 60.83 ? 304 ASP A CB 1 ATOM 2273 C CG . ASP A 1 303 ? -46.220 -33.064 67.612 1.00 68.25 ? 304 ASP A CG 1 ATOM 2274 O OD1 . ASP A 1 303 ? -46.522 -31.851 67.764 1.00 65.04 ? 304 ASP A OD1 1 ATOM 2275 O OD2 . ASP A 1 303 ? -45.253 -33.590 68.226 1.00 72.08 ? 304 ASP A OD2 1 ATOM 2276 N N . GLY A 1 304 ? -49.599 -32.031 67.986 1.00 62.40 ? 305 GLY A N 1 ATOM 2277 C CA . GLY A 1 304 ? -50.381 -31.910 69.208 1.00 56.11 ? 305 GLY A CA 1 ATOM 2278 C C . GLY A 1 304 ? -49.533 -31.753 70.470 1.00 62.82 ? 305 GLY A C 1 ATOM 2279 O O . GLY A 1 304 ? -50.048 -31.383 71.523 1.00 68.05 ? 305 GLY A O 1 ATOM 2280 N N . ASP A 1 305 ? -48.233 -32.031 70.365 1.00 62.63 ? 306 ASP A N 1 ATOM 2281 C CA . ASP A 1 305 ? -47.306 -31.891 71.489 1.00 63.94 ? 306 ASP A CA 1 ATOM 2282 C C . ASP A 1 305 ? -46.589 -30.525 71.529 1.00 66.62 ? 306 ASP A C 1 ATOM 2283 O O . ASP A 1 305 ? -47.037 -29.596 72.229 1.00 62.06 ? 306 ASP A O 1 ATOM 2284 C CB . ASP A 1 305 ? -46.288 -33.039 71.486 1.00 64.31 ? 306 ASP A CB 1 ATOM 2285 C CG . ASP A 1 305 ? -45.365 -33.014 72.700 1.00 72.72 ? 306 ASP A CG 1 ATOM 2286 O OD1 . ASP A 1 305 ? -45.693 -32.342 73.709 1.00 77.88 ? 306 ASP A OD1 1 ATOM 2287 O OD2 . ASP A 1 305 ? -44.307 -33.676 72.646 1.00 76.31 ? 306 ASP A OD2 1 ATOM 2288 N N . PHE A 1 306 ? -45.474 -30.413 70.801 1.00 57.98 ? 307 PHE A N 1 ATOM 2289 C CA . PHE A 1 306 ? -44.725 -29.163 70.767 1.00 51.90 ? 307 PHE A CA 1 ATOM 2290 C C . PHE A 1 306 ? -45.638 -28.030 70.281 1.00 58.34 ? 307 PHE A C 1 ATOM 2291 O O . PHE A 1 306 ? -45.586 -26.912 70.777 1.00 59.92 ? 307 PHE A O 1 ATOM 2292 C CB . PHE A 1 306 ? -43.470 -29.280 69.887 1.00 50.46 ? 307 PHE A CB 1 ATOM 2293 C CG . PHE A 1 306 ? -42.510 -28.126 70.052 1.00 51.08 ? 307 PHE A CG 1 ATOM 2294 C CD1 . PHE A 1 306 ? -42.822 -26.862 69.569 1.00 55.94 ? 307 PHE A CD1 1 ATOM 2295 C CD2 . PHE A 1 306 ? -41.304 -28.294 70.710 1.00 52.58 ? 307 PHE A CD2 1 ATOM 2296 C CE1 . PHE A 1 306 ? -41.953 -25.789 69.740 1.00 51.79 ? 307 PHE A CE1 1 ATOM 2297 C CE2 . PHE A 1 306 ? -40.426 -27.221 70.878 1.00 53.29 ? 307 PHE A CE2 1 ATOM 2298 C CZ . PHE A 1 306 ? -40.760 -25.970 70.394 1.00 49.16 ? 307 PHE A CZ 1 ATOM 2299 N N . LEU A 1 307 ? -46.476 -28.328 69.300 1.00 60.76 ? 308 LEU A N 1 ATOM 2300 C CA . LEU A 1 307 ? -47.468 -27.377 68.839 1.00 53.54 ? 308 LEU A CA 1 ATOM 2301 C C . LEU A 1 307 ? -48.805 -28.022 69.092 1.00 55.91 ? 308 LEU A C 1 ATOM 2302 O O . LEU A 1 307 ? -49.013 -29.168 68.725 1.00 64.09 ? 308 LEU A O 1 ATOM 2303 C CB . LEU A 1 307 ? -47.263 -27.094 67.357 1.00 59.17 ? 308 LEU A CB 1 ATOM 2304 C CG . LEU A 1 307 ? -45.987 -26.309 67.060 1.00 53.15 ? 308 LEU A CG 1 ATOM 2305 C CD1 . LEU A 1 307 ? -45.716 -26.202 65.558 1.00 56.59 ? 308 LEU A CD1 1 ATOM 2306 C CD2 . LEU A 1 307 ? -46.117 -24.938 67.706 1.00 53.98 ? 308 LEU A CD2 1 ATOM 2307 N N . SER A 1 308 ? -49.709 -27.313 69.745 1.00 54.18 ? 309 SER A N 1 ATOM 2308 C CA . SER A 1 308 ? -50.938 -27.954 70.157 1.00 55.76 ? 309 SER A CA 1 ATOM 2309 C C . SER A 1 308 ? -51.949 -27.853 69.017 1.00 59.17 ? 309 SER A C 1 ATOM 2310 O O . SER A 1 308 ? -53.009 -28.489 69.040 1.00 55.11 ? 309 SER A O 1 ATOM 2311 C CB . SER A 1 308 ? -51.454 -27.358 71.483 1.00 49.33 ? 309 SER A CB 1 ATOM 2312 O OG . SER A 1 308 ? -52.235 -26.197 71.274 1.00 58.96 ? 309 SER A OG 1 ATOM 2313 N N . ASP A 1 309 ? -51.582 -27.069 68.003 1.00 59.05 ? 310 ASP A N 1 ATOM 2314 C CA . ASP A 1 309 ? -52.411 -26.837 66.827 1.00 54.38 ? 310 ASP A CA 1 ATOM 2315 C C . ASP A 1 309 ? -51.512 -26.264 65.720 1.00 61.74 ? 310 ASP A C 1 ATOM 2316 O O . ASP A 1 309 ? -50.292 -26.175 65.911 1.00 62.11 ? 310 ASP A O 1 ATOM 2317 C CB . ASP A 1 309 ? -53.534 -25.860 67.177 1.00 57.86 ? 310 ASP A CB 1 ATOM 2318 C CG . ASP A 1 309 ? -54.673 -25.878 66.168 1.00 65.42 ? 310 ASP A CG 1 ATOM 2319 O OD1 . ASP A 1 309 ? -54.470 -26.373 65.034 1.00 69.56 ? 310 ASP A OD1 1 ATOM 2320 O OD2 . ASP A 1 309 ? -55.766 -25.374 66.509 1.00 61.13 ? 310 ASP A OD2 1 ATOM 2321 N N . THR A 1 310 ? -52.082 -25.891 64.569 1.00 52.46 ? 311 THR A N 1 ATOM 2322 C CA . THR A 1 310 ? -51.271 -25.318 63.487 1.00 58.10 ? 311 THR A CA 1 ATOM 2323 C C . THR A 1 310 ? -50.806 -23.937 63.917 1.00 56.88 ? 311 THR A C 1 ATOM 2324 O O . THR A 1 310 ? -51.499 -23.271 64.691 1.00 55.77 ? 311 THR A O 1 ATOM 2325 C CB . THR A 1 310 ? -52.064 -25.146 62.172 1.00 57.92 ? 311 THR A CB 1 ATOM 2326 O OG1 . THR A 1 310 ? -52.925 -24.002 62.278 1.00 61.63 ? 311 THR A OG1 1 ATOM 2327 C CG2 . THR A 1 310 ? -52.892 -26.377 61.867 1.00 54.31 ? 311 THR A CG2 1 ATOM 2328 N N . PRO A 1 311 ? -49.634 -23.501 63.425 1.00 54.86 ? 312 PRO A N 1 ATOM 2329 C CA . PRO A 1 311 ? -49.131 -22.171 63.775 1.00 51.08 ? 312 PRO A CA 1 ATOM 2330 C C . PRO A 1 311 ? -50.168 -21.073 63.529 1.00 60.09 ? 312 PRO A C 1 ATOM 2331 O O . PRO A 1 311 ? -50.315 -20.185 64.381 1.00 60.46 ? 312 PRO A O 1 ATOM 2332 C CB . PRO A 1 311 ? -47.917 -22.012 62.866 1.00 52.79 ? 312 PRO A CB 1 ATOM 2333 C CG . PRO A 1 311 ? -47.404 -23.402 62.702 1.00 50.84 ? 312 PRO A CG 1 ATOM 2334 C CD . PRO A 1 311 ? -48.634 -24.286 62.679 1.00 55.99 ? 312 PRO A CD 1 ATOM 2335 N N . GLU A 1 312 ? -50.902 -21.158 62.421 1.00 49.77 ? 313 GLU A N 1 ATOM 2336 C CA . GLU A 1 312 ? -51.955 -20.186 62.132 1.00 54.95 ? 313 GLU A CA 1 ATOM 2337 C C . GLU A 1 312 ? -53.075 -20.151 63.199 1.00 55.57 ? 313 GLU A C 1 ATOM 2338 O O . GLU A 1 312 ? -53.488 -19.082 63.640 1.00 55.05 ? 313 GLU A O 1 ATOM 2339 C CB . GLU A 1 312 ? -52.528 -20.415 60.720 1.00 61.25 ? 313 GLU A CB 1 ATOM 2340 C CG . GLU A 1 312 ? -53.890 -19.755 60.481 1.00 68.05 ? 313 GLU A CG 1 ATOM 2341 C CD . GLU A 1 312 ? -54.335 -19.785 59.016 1.00 93.81 ? 313 GLU A CD 1 ATOM 2342 O OE1 . GLU A 1 312 ? -55.561 -19.676 58.763 1.00 88.47 ? 313 GLU A OE1 1 ATOM 2343 O OE2 . GLU A 1 312 ? -53.463 -19.906 58.121 1.00 96.80 ? 313 GLU A OE2 1 ATOM 2344 N N . ALA A 1 313 ? -53.571 -21.309 63.614 1.00 52.59 ? 314 ALA A N 1 ATOM 2345 C CA . ALA A 1 313 ? -54.619 -21.338 64.632 1.00 52.52 ? 314 ALA A CA 1 ATOM 2346 C C . ALA A 1 313 ? -54.139 -20.782 65.973 1.00 62.66 ? 314 ALA A C 1 ATOM 2347 O O . ALA A 1 313 ? -54.919 -20.170 66.713 1.00 62.01 ? 314 ALA A O 1 ATOM 2348 C CB . ALA A 1 313 ? -55.144 -22.750 64.825 1.00 54.39 ? 314 ALA A CB 1 ATOM 2349 N N . LEU A 1 314 ? -52.865 -21.014 66.297 1.00 60.20 ? 315 LEU A N 1 ATOM 2350 C CA . LEU A 1 314 ? -52.305 -20.525 67.563 1.00 61.95 ? 315 LEU A CA 1 ATOM 2351 C C . LEU A 1 314 ? -52.095 -19.016 67.502 1.00 62.73 ? 315 LEU A C 1 ATOM 2352 O O . LEU A 1 314 ? -52.383 -18.308 68.460 1.00 63.45 ? 315 LEU A O 1 ATOM 2353 C CB . LEU A 1 314 ? -50.996 -21.238 67.911 1.00 49.48 ? 315 LEU A CB 1 ATOM 2354 C CG . LEU A 1 314 ? -51.133 -22.726 68.247 1.00 50.79 ? 315 LEU A CG 1 ATOM 2355 C CD1 . LEU A 1 314 ? -49.773 -23.406 68.195 1.00 45.81 ? 315 LEU A CD1 1 ATOM 2356 C CD2 . LEU A 1 314 ? -51.777 -22.902 69.598 1.00 41.98 ? 315 LEU A CD2 1 ATOM 2357 N N . ILE A 1 315 ? -51.612 -18.522 66.367 1.00 53.13 ? 316 ILE A N 1 ATOM 2358 C CA . ILE A 1 315 ? -51.402 -17.095 66.223 1.00 52.59 ? 316 ILE A CA 1 ATOM 2359 C C . ILE A 1 315 ? -52.729 -16.362 66.353 1.00 61.37 ? 316 ILE A C 1 ATOM 2360 O O . ILE A 1 315 ? -52.825 -15.341 67.032 1.00 67.85 ? 316 ILE A O 1 ATOM 2361 C CB . ILE A 1 315 ? -50.729 -16.764 64.892 1.00 51.29 ? 316 ILE A CB 1 ATOM 2362 C CG1 . ILE A 1 315 ? -49.257 -17.138 64.949 1.00 51.02 ? 316 ILE A CG1 1 ATOM 2363 C CG2 . ILE A 1 315 ? -50.873 -15.305 64.564 1.00 49.25 ? 316 ILE A CG2 1 ATOM 2364 C CD1 . ILE A 1 315 ? -48.656 -17.451 63.593 1.00 46.57 ? 316 ILE A CD1 1 ATOM 2365 N N . ASN A 1 316 ? -53.763 -16.907 65.725 1.00 63.91 ? 317 ASN A N 1 ATOM 2366 C CA . ASN A 1 316 ? -55.073 -16.266 65.729 1.00 65.32 ? 317 ASN A CA 1 ATOM 2367 C C . ASN A 1 316 ? -55.722 -16.202 67.110 1.00 59.95 ? 317 ASN A C 1 ATOM 2368 O O . ASN A 1 316 ? -56.334 -15.194 67.463 1.00 62.48 ? 317 ASN A O 1 ATOM 2369 C CB . ASN A 1 316 ? -56.005 -16.942 64.721 1.00 58.78 ? 317 ASN A CB 1 ATOM 2370 C CG . ASN A 1 316 ? -55.657 -16.591 63.298 1.00 60.20 ? 317 ASN A CG 1 ATOM 2371 O OD1 . ASN A 1 316 ? -54.904 -15.649 63.056 1.00 65.32 ? 317 ASN A OD1 1 ATOM 2372 N ND2 . ASN A 1 316 ? -56.207 -17.340 62.340 1.00 57.94 ? 317 ASN A ND2 1 ATOM 2373 N N . ALA A 1 317 ? -55.574 -17.279 67.878 1.00 59.46 ? 318 ALA A N 1 ATOM 2374 C CA . ALA A 1 317 ? -56.181 -17.401 69.211 1.00 65.07 ? 318 ALA A CA 1 ATOM 2375 C C . ALA A 1 317 ? -55.360 -16.779 70.344 1.00 63.27 ? 318 ALA A C 1 ATOM 2376 O O . ALA A 1 317 ? -55.911 -16.390 71.363 1.00 69.52 ? 318 ALA A O 1 ATOM 2377 C CB . ALA A 1 317 ? -56.454 -18.873 69.533 1.00 54.87 ? 318 ALA A CB 1 ATOM 2378 N N . GLY A 1 318 ? -54.047 -16.689 70.154 1.00 69.31 ? 319 GLY A N 1 ATOM 2379 C CA . GLY A 1 318 ? -53.124 -16.342 71.222 1.00 64.90 ? 319 GLY A CA 1 ATOM 2380 C C . GLY A 1 318 ? -53.262 -14.972 71.862 1.00 67.10 ? 319 GLY A C 1 ATOM 2381 O O . GLY A 1 318 ? -53.724 -14.014 71.227 1.00 61.17 ? 319 GLY A O 1 ATOM 2382 N N . ASP A 1 319 ? -52.859 -14.897 73.134 1.00 65.66 ? 320 ASP A N 1 ATOM 2383 C CA . ASP A 1 319 ? -52.717 -13.631 73.857 1.00 59.73 ? 320 ASP A CA 1 ATOM 2384 C C . ASP A 1 319 ? -51.237 -13.242 73.918 1.00 60.08 ? 320 ASP A C 1 ATOM 2385 O O . ASP A 1 319 ? -50.391 -14.051 74.302 1.00 67.19 ? 320 ASP A O 1 ATOM 2386 C CB . ASP A 1 319 ? -53.260 -13.781 75.267 1.00 64.69 ? 320 ASP A CB 1 ATOM 2387 C CG . ASP A 1 319 ? -53.518 -12.448 75.948 1.00 70.15 ? 320 ASP A CG 1 ATOM 2388 O OD1 . ASP A 1 319 ? -52.921 -11.421 75.553 1.00 67.46 ? 320 ASP A OD1 1 ATOM 2389 O OD2 . ASP A 1 319 ? -54.335 -12.436 76.890 1.00 70.47 ? 320 ASP A OD2 1 ATOM 2390 N N . PHE A 1 320 ? -50.927 -12.005 73.544 1.00 56.34 ? 321 PHE A N 1 ATOM 2391 C CA . PHE A 1 320 ? -49.535 -11.585 73.416 1.00 60.33 ? 321 PHE A CA 1 ATOM 2392 C C . PHE A 1 320 ? -49.213 -10.304 74.190 1.00 61.49 ? 321 PHE A C 1 ATOM 2393 O O . PHE A 1 320 ? -48.206 -9.649 73.926 1.00 63.71 ? 321 PHE A O 1 ATOM 2394 C CB . PHE A 1 320 ? -49.141 -11.423 71.930 1.00 66.61 ? 321 PHE A CB 1 ATOM 2395 C CG . PHE A 1 320 ? -49.290 -12.685 71.111 1.00 63.30 ? 321 PHE A CG 1 ATOM 2396 C CD1 . PHE A 1 320 ? -48.361 -13.712 71.218 1.00 55.15 ? 321 PHE A CD1 1 ATOM 2397 C CD2 . PHE A 1 320 ? -50.363 -12.842 70.233 1.00 60.28 ? 321 PHE A CD2 1 ATOM 2398 C CE1 . PHE A 1 320 ? -48.502 -14.882 70.464 1.00 62.40 ? 321 PHE A CE1 1 ATOM 2399 C CE2 . PHE A 1 320 ? -50.508 -14.011 69.481 1.00 59.94 ? 321 PHE A CE2 1 ATOM 2400 C CZ . PHE A 1 320 ? -49.576 -15.030 69.590 1.00 51.63 ? 321 PHE A CZ 1 ATOM 2401 N N . HIS A 1 321 ? -50.066 -9.939 75.141 1.00 65.91 ? 322 HIS A N 1 ATOM 2402 C CA . HIS A 1 321 ? -49.742 -8.840 76.054 1.00 69.56 ? 322 HIS A CA 1 ATOM 2403 C C . HIS A 1 321 ? -48.441 -9.136 76.815 1.00 64.18 ? 322 HIS A C 1 ATOM 2404 O O . HIS A 1 321 ? -48.206 -10.262 77.256 1.00 58.79 ? 322 HIS A O 1 ATOM 2405 C CB . HIS A 1 321 ? -50.896 -8.563 77.027 1.00 64.34 ? 322 HIS A CB 1 ATOM 2406 C CG . HIS A 1 321 ? -52.110 -7.960 76.377 1.00 77.93 ? 322 HIS A CG 1 ATOM 2407 N ND1 . HIS A 1 321 ? -53.109 -8.723 75.806 1.00 80.79 ? 322 HIS A ND1 1 ATOM 2408 C CD2 . HIS A 1 321 ? -52.479 -6.668 76.203 1.00 72.29 ? 322 HIS A CD2 1 ATOM 2409 C CE1 . HIS A 1 321 ? -54.045 -7.926 75.317 1.00 75.98 ? 322 HIS A CE1 1 ATOM 2410 N NE2 . HIS A 1 321 ? -53.687 -6.675 75.544 1.00 70.06 ? 322 HIS A NE2 1 ATOM 2411 N N . GLY A 1 322 ? -47.578 -8.132 76.925 1.00 61.73 ? 323 GLY A N 1 ATOM 2412 C CA . GLY A 1 322 ? -46.311 -8.299 77.610 1.00 55.27 ? 323 GLY A CA 1 ATOM 2413 C C . GLY A 1 322 ? -45.138 -8.555 76.682 1.00 63.17 ? 323 GLY A C 1 ATOM 2414 O O . GLY A 1 322 ? -43.993 -8.677 77.130 1.00 60.83 ? 323 GLY A O 1 ATOM 2415 N N . LEU A 1 323 ? -45.412 -8.625 75.382 1.00 63.58 ? 324 LEU A N 1 ATOM 2416 C CA . LEU A 1 323 ? -44.393 -9.037 74.429 1.00 52.04 ? 324 LEU A CA 1 ATOM 2417 C C . LEU A 1 323 ? -43.909 -7.886 73.558 1.00 49.25 ? 324 LEU A C 1 ATOM 2418 O O . LEU A 1 323 ? -44.685 -7.044 73.138 1.00 53.32 ? 324 LEU A O 1 ATOM 2419 C CB . LEU A 1 323 ? -44.942 -10.167 73.561 1.00 65.99 ? 324 LEU A CB 1 ATOM 2420 C CG . LEU A 1 323 ? -43.957 -11.133 72.906 1.00 68.31 ? 324 LEU A CG 1 ATOM 2421 C CD1 . LEU A 1 323 ? -43.113 -11.855 73.957 1.00 63.36 ? 324 LEU A CD1 1 ATOM 2422 C CD2 . LEU A 1 323 ? -44.751 -12.113 72.082 1.00 69.46 ? 324 LEU A CD2 1 ATOM 2423 N N . GLN A 1 324 ? -42.609 -7.843 73.313 1.00 50.92 ? 325 GLN A N 1 ATOM 2424 C CA . GLN A 1 324 ? -42.061 -6.991 72.268 1.00 56.49 ? 325 GLN A CA 1 ATOM 2425 C C . GLN A 1 324 ? -41.467 -7.893 71.196 1.00 53.18 ? 325 GLN A C 1 ATOM 2426 O O . GLN A 1 324 ? -40.665 -8.778 71.496 1.00 48.45 ? 325 GLN A O 1 ATOM 2427 C CB . GLN A 1 324 ? -40.987 -6.031 72.790 1.00 54.55 ? 325 GLN A CB 1 ATOM 2428 C CG . GLN A 1 324 ? -41.438 -5.081 73.892 1.00 59.24 ? 325 GLN A CG 1 ATOM 2429 C CD . GLN A 1 324 ? -41.474 -5.752 75.251 1.00 57.88 ? 325 GLN A CD 1 ATOM 2430 O OE1 . GLN A 1 324 ? -40.531 -6.447 75.652 1.00 59.43 ? 325 GLN A OE1 1 ATOM 2431 N NE2 . GLN A 1 324 ? -42.582 -5.585 75.948 1.00 56.93 ? 325 GLN A NE2 1 ATOM 2432 N N . VAL A 1 325 ? -41.878 -7.671 69.950 1.00 54.15 ? 326 VAL A N 1 ATOM 2433 C CA . VAL A 1 325 ? -41.372 -8.453 68.823 1.00 53.02 ? 326 VAL A CA 1 ATOM 2434 C C . VAL A 1 325 ? -40.843 -7.529 67.745 1.00 53.23 ? 326 VAL A C 1 ATOM 2435 O O . VAL A 1 325 ? -41.494 -6.549 67.383 1.00 54.78 ? 326 VAL A O 1 ATOM 2436 C CB . VAL A 1 325 ? -42.470 -9.323 68.198 1.00 50.49 ? 326 VAL A CB 1 ATOM 2437 C CG1 . VAL A 1 325 ? -41.905 -10.161 67.069 1.00 55.98 ? 326 VAL A CG1 1 ATOM 2438 C CG2 . VAL A 1 325 ? -43.111 -10.217 69.245 1.00 50.62 ? 326 VAL A CG2 1 ATOM 2439 N N . LEU A 1 326 ? -39.652 -7.836 67.247 1.00 52.01 ? 327 LEU A N 1 ATOM 2440 C CA . LEU A 1 326 ? -39.101 -7.149 66.089 1.00 51.73 ? 327 LEU A CA 1 ATOM 2441 C C . LEU A 1 326 ? -39.127 -8.083 64.849 1.00 52.90 ? 327 LEU A C 1 ATOM 2442 O O . LEU A 1 326 ? -38.551 -9.169 64.884 1.00 56.58 ? 327 LEU A O 1 ATOM 2443 C CB . LEU A 1 326 ? -37.677 -6.688 66.409 1.00 51.69 ? 327 LEU A CB 1 ATOM 2444 C CG . LEU A 1 326 ? -36.871 -5.986 65.317 1.00 57.22 ? 327 LEU A CG 1 ATOM 2445 C CD1 . LEU A 1 326 ? -37.507 -4.657 64.971 1.00 62.25 ? 327 LEU A CD1 1 ATOM 2446 C CD2 . LEU A 1 326 ? -35.441 -5.784 65.749 1.00 59.07 ? 327 LEU A CD2 1 ATOM 2447 N N . VAL A 1 327 ? -39.805 -7.679 63.772 1.00 54.68 ? 328 VAL A N 1 ATOM 2448 C CA . VAL A 1 327 ? -39.873 -8.502 62.539 1.00 57.63 ? 328 VAL A CA 1 ATOM 2449 C C . VAL A 1 327 ? -39.366 -7.782 61.275 1.00 58.19 ? 328 VAL A C 1 ATOM 2450 O O . VAL A 1 327 ? -39.458 -6.558 61.170 1.00 57.03 ? 328 VAL A O 1 ATOM 2451 C CB . VAL A 1 327 ? -41.315 -9.035 62.241 1.00 48.66 ? 328 VAL A CB 1 ATOM 2452 C CG1 . VAL A 1 327 ? -41.866 -9.832 63.416 1.00 58.13 ? 328 VAL A CG1 1 ATOM 2453 C CG2 . VAL A 1 327 ? -42.254 -7.902 61.891 1.00 52.76 ? 328 VAL A CG2 1 ATOM 2454 N N . GLY A 1 328 ? -38.847 -8.546 60.314 1.00 49.83 ? 329 GLY A N 1 ATOM 2455 C CA . GLY A 1 328 ? -38.405 -7.969 59.065 1.00 50.10 ? 329 GLY A CA 1 ATOM 2456 C C . GLY A 1 328 ? -37.996 -8.918 57.958 1.00 55.60 ? 329 GLY A C 1 ATOM 2457 O O . GLY A 1 328 ? -37.913 -10.138 58.147 1.00 55.43 ? 329 GLY A O 1 ATOM 2458 N N . VAL A 1 329 ? -37.734 -8.327 56.792 1.00 52.30 ? 330 VAL A N 1 ATOM 2459 C CA . VAL A 1 329 ? -37.448 -9.048 55.545 1.00 52.71 ? 330 VAL A CA 1 ATOM 2460 C C . VAL A 1 329 ? -36.410 -8.285 54.720 1.00 47.09 ? 330 VAL A C 1 ATOM 2461 O O . VAL A 1 329 ? -36.283 -7.070 54.839 1.00 52.75 ? 330 VAL A O 1 ATOM 2462 C CB . VAL A 1 329 ? -38.716 -9.189 54.677 1.00 54.38 ? 330 VAL A CB 1 ATOM 2463 C CG1 . VAL A 1 329 ? -39.759 -10.087 55.353 1.00 44.05 ? 330 VAL A CG1 1 ATOM 2464 C CG2 . VAL A 1 329 ? -39.310 -7.811 54.346 1.00 50.04 ? 330 VAL A CG2 1 ATOM 2465 N N . VAL A 1 330 ? -35.651 -8.991 53.894 1.00 52.34 ? 331 VAL A N 1 ATOM 2466 C CA . VAL A 1 330 ? -34.801 -8.315 52.905 1.00 60.68 ? 331 VAL A CA 1 ATOM 2467 C C . VAL A 1 330 ? -35.597 -7.835 51.673 1.00 52.66 ? 331 VAL A C 1 ATOM 2468 O O . VAL A 1 330 ? -36.756 -8.206 51.481 1.00 50.52 ? 331 VAL A O 1 ATOM 2469 C CB . VAL A 1 330 ? -33.631 -9.200 52.464 1.00 60.23 ? 331 VAL A CB 1 ATOM 2470 C CG1 . VAL A 1 330 ? -32.884 -9.692 53.693 1.00 60.12 ? 331 VAL A CG1 1 ATOM 2471 C CG2 . VAL A 1 330 ? -34.132 -10.361 51.630 1.00 50.51 ? 331 VAL A CG2 1 ATOM 2472 N N . LYS A 1 331 ? -34.975 -6.992 50.854 1.00 61.54 ? 332 LYS A N 1 ATOM 2473 C CA . LYS A 1 331 ? -35.656 -6.404 49.696 1.00 57.34 ? 332 LYS A CA 1 ATOM 2474 C C . LYS A 1 331 ? -36.104 -7.464 48.690 1.00 59.75 ? 332 LYS A C 1 ATOM 2475 O O . LYS A 1 331 ? -37.217 -7.389 48.176 1.00 64.64 ? 332 LYS A O 1 ATOM 2476 C CB . LYS A 1 331 ? -34.787 -5.337 49.022 1.00 62.09 ? 332 LYS A CB 1 ATOM 2477 C CG . LYS A 1 331 ? -35.537 -4.448 48.011 1.00 68.27 ? 332 LYS A CG 1 ATOM 2478 C CD . LYS A 1 331 ? -34.682 -3.255 47.563 1.00 66.09 ? 332 LYS A CD 1 ATOM 2479 C CE . LYS A 1 331 ? -35.424 -2.328 46.599 1.00 80.86 ? 332 LYS A CE 1 ATOM 2480 N NZ . LYS A 1 331 ? -35.369 -2.780 45.171 1.00 84.26 ? 332 LYS A NZ 1 ATOM 2481 N N . ASP A 1 332 ? -35.251 -8.457 48.434 1.00 51.59 ? 333 ASP A N 1 ATOM 2482 C CA . ASP A 1 332 ? -35.560 -9.490 47.451 1.00 53.83 ? 333 ASP A CA 1 ATOM 2483 C C . ASP A 1 332 ? -35.475 -10.898 48.033 1.00 58.66 ? 333 ASP A C 1 ATOM 2484 O O . ASP A 1 332 ? -34.499 -11.626 47.800 1.00 62.79 ? 333 ASP A O 1 ATOM 2485 C CB . ASP A 1 332 ? -34.638 -9.375 46.227 1.00 62.23 ? 333 ASP A CB 1 ATOM 2486 C CG . ASP A 1 332 ? -34.601 -7.965 45.644 1.00 62.95 ? 333 ASP A CG 1 ATOM 2487 O OD1 . ASP A 1 332 ? -35.673 -7.412 45.314 1.00 70.85 ? 333 ASP A OD1 1 ATOM 2488 O OD2 . ASP A 1 332 ? -33.494 -7.404 45.534 1.00 63.02 ? 333 ASP A OD2 1 ATOM 2489 N N . GLU A 1 333 ? -36.512 -11.285 48.772 1.00 55.37 ? 334 GLU A N 1 ATOM 2490 C CA . GLU A 1 333 ? -36.578 -12.612 49.377 1.00 51.65 ? 334 GLU A CA 1 ATOM 2491 C C . GLU A 1 333 ? -36.492 -13.770 48.375 1.00 60.02 ? 334 GLU A C 1 ATOM 2492 O O . GLU A 1 333 ? -35.848 -14.788 48.651 1.00 62.61 ? 334 GLU A O 1 ATOM 2493 C CB . GLU A 1 333 ? -37.858 -12.748 50.204 1.00 61.09 ? 334 GLU A CB 1 ATOM 2494 C CG . GLU A 1 333 ? -37.927 -11.849 51.460 1.00 60.38 ? 334 GLU A CG 1 ATOM 2495 C CD . GLU A 1 333 ? -36.958 -12.274 52.570 1.00 64.86 ? 334 GLU A CD 1 ATOM 2496 O OE1 . GLU A 1 333 ? -36.550 -13.464 52.614 1.00 61.53 ? 334 GLU A OE1 1 ATOM 2497 O OE2 . GLU A 1 333 ? -36.612 -11.411 53.411 1.00 66.92 ? 334 GLU A OE2 1 ATOM 2498 N N . GLY A 1 334 ? -37.125 -13.610 47.210 1.00 61.75 ? 335 GLY A N 1 ATOM 2499 C CA . GLY A 1 334 ? -37.328 -14.724 46.295 1.00 48.38 ? 335 GLY A CA 1 ATOM 2500 C C . GLY A 1 334 ? -36.146 -15.128 45.438 1.00 54.14 ? 335 GLY A C 1 ATOM 2501 O O . GLY A 1 334 ? -35.939 -16.315 45.170 1.00 55.51 ? 335 GLY A O 1 ATOM 2502 N N . SER A 1 335 ? -35.359 -14.139 45.028 1.00 57.88 ? 336 SER A N 1 ATOM 2503 C CA . SER A 1 335 ? -34.406 -14.294 43.925 1.00 59.16 ? 336 SER A CA 1 ATOM 2504 C C . SER A 1 335 ? -33.410 -15.449 44.057 1.00 60.48 ? 336 SER A C 1 ATOM 2505 O O . SER A 1 335 ? -33.114 -16.134 43.076 1.00 68.14 ? 336 SER A O 1 ATOM 2506 C CB . SER A 1 335 ? -33.663 -12.975 43.674 1.00 59.33 ? 336 SER A CB 1 ATOM 2507 O OG . SER A 1 335 ? -32.653 -12.766 44.643 1.00 66.24 ? 336 SER A OG 1 ATOM 2508 N N . TYR A 1 336 ? -32.897 -15.644 45.265 1.00 62.71 ? 337 TYR A N 1 ATOM 2509 C CA . TYR A 1 336 ? -31.902 -16.675 45.557 1.00 63.07 ? 337 TYR A CA 1 ATOM 2510 C C . TYR A 1 336 ? -32.398 -18.056 45.127 1.00 62.04 ? 337 TYR A C 1 ATOM 2511 O O . TYR A 1 336 ? -31.644 -18.846 44.561 1.00 65.47 ? 337 TYR A O 1 ATOM 2512 C CB . TYR A 1 336 ? -31.539 -16.642 47.073 1.00 67.79 ? 337 TYR A CB 1 ATOM 2513 C CG . TYR A 1 336 ? -30.992 -17.940 47.649 1.00 61.03 ? 337 TYR A CG 1 ATOM 2514 C CD1 . TYR A 1 336 ? -29.756 -18.433 47.257 1.00 71.20 ? 337 TYR A CD1 1 ATOM 2515 C CD2 . TYR A 1 336 ? -31.714 -18.670 48.588 1.00 65.92 ? 337 TYR A CD2 1 ATOM 2516 C CE1 . TYR A 1 336 ? -29.254 -19.626 47.777 1.00 71.00 ? 337 TYR A CE1 1 ATOM 2517 C CE2 . TYR A 1 336 ? -31.224 -19.865 49.112 1.00 63.41 ? 337 TYR A CE2 1 ATOM 2518 C CZ . TYR A 1 336 ? -29.993 -20.335 48.700 1.00 70.13 ? 337 TYR A CZ 1 ATOM 2519 O OH . TYR A 1 336 ? -29.489 -21.515 49.204 1.00 80.05 ? 337 TYR A OH 1 ATOM 2520 N N . PHE A 1 337 ? -33.681 -18.324 45.357 1.00 56.70 ? 338 PHE A N 1 ATOM 2521 C CA . PHE A 1 337 ? -34.197 -19.686 45.263 1.00 57.74 ? 338 PHE A CA 1 ATOM 2522 C C . PHE A 1 337 ? -34.478 -20.163 43.841 1.00 65.59 ? 338 PHE A C 1 ATOM 2523 O O . PHE A 1 337 ? -34.531 -21.378 43.595 1.00 58.78 ? 338 PHE A O 1 ATOM 2524 C CB . PHE A 1 337 ? -35.458 -19.843 46.113 1.00 58.24 ? 338 PHE A CB 1 ATOM 2525 C CG . PHE A 1 337 ? -35.218 -19.686 47.592 1.00 56.57 ? 338 PHE A CG 1 ATOM 2526 C CD1 . PHE A 1 337 ? -35.319 -18.438 48.197 1.00 51.58 ? 338 PHE A CD1 1 ATOM 2527 C CD2 . PHE A 1 337 ? -34.891 -20.788 48.376 1.00 59.69 ? 338 PHE A CD2 1 ATOM 2528 C CE1 . PHE A 1 337 ? -35.088 -18.297 49.571 1.00 69.39 ? 338 PHE A CE1 1 ATOM 2529 C CE2 . PHE A 1 337 ? -34.669 -20.654 49.750 1.00 56.42 ? 338 PHE A CE2 1 ATOM 2530 C CZ . PHE A 1 337 ? -34.766 -19.409 50.349 1.00 52.14 ? 338 PHE A CZ 1 ATOM 2531 N N . LEU A 1 338 ? -34.642 -19.206 42.922 1.00 62.21 ? 339 LEU A N 1 ATOM 2532 C CA . LEU A 1 338 ? -35.086 -19.476 41.555 1.00 59.17 ? 339 LEU A CA 1 ATOM 2533 C C . LEU A 1 338 ? -34.096 -20.319 40.762 1.00 61.55 ? 339 LEU A C 1 ATOM 2534 O O . LEU A 1 338 ? -34.485 -21.048 39.851 1.00 59.48 ? 339 LEU A O 1 ATOM 2535 C CB . LEU A 1 338 ? -35.385 -18.165 40.823 1.00 55.98 ? 339 LEU A CB 1 ATOM 2536 C CG . LEU A 1 338 ? -36.503 -17.389 41.507 1.00 59.15 ? 339 LEU A CG 1 ATOM 2537 C CD1 . LEU A 1 338 ? -36.805 -16.060 40.832 1.00 57.73 ? 339 LEU A CD1 1 ATOM 2538 C CD2 . LEU A 1 338 ? -37.733 -18.273 41.558 1.00 59.39 ? 339 LEU A CD2 1 ATOM 2539 N N . VAL A 1 339 ? -32.819 -20.233 41.127 1.00 63.15 ? 340 VAL A N 1 ATOM 2540 C CA . VAL A 1 339 ? -31.756 -20.937 40.405 1.00 60.02 ? 340 VAL A CA 1 ATOM 2541 C C . VAL A 1 339 ? -31.706 -22.400 40.795 1.00 55.03 ? 340 VAL A C 1 ATOM 2542 O O . VAL A 1 339 ? -30.845 -23.140 40.350 1.00 56.87 ? 340 VAL A O 1 ATOM 2543 C CB . VAL A 1 339 ? -30.380 -20.303 40.667 1.00 62.14 ? 340 VAL A CB 1 ATOM 2544 C CG1 . VAL A 1 339 ? -30.408 -18.832 40.290 1.00 57.05 ? 340 VAL A CG1 1 ATOM 2545 C CG2 . VAL A 1 339 ? -29.971 -20.484 42.152 1.00 62.26 ? 340 VAL A CG2 1 ATOM 2546 N N . TYR A 1 340 ? -32.640 -22.810 41.640 1.00 65.16 ? 341 TYR A N 1 ATOM 2547 C CA . TYR A 1 340 ? -32.709 -24.191 42.097 1.00 63.97 ? 341 TYR A CA 1 ATOM 2548 C C . TYR A 1 340 ? -33.749 -24.981 41.293 1.00 62.97 ? 341 TYR A C 1 ATOM 2549 O O . TYR A 1 340 ? -34.137 -26.090 41.682 1.00 59.22 ? 341 TYR A O 1 ATOM 2550 C CB . TYR A 1 340 ? -32.971 -24.261 43.614 1.00 56.23 ? 341 TYR A CB 1 ATOM 2551 C CG . TYR A 1 340 ? -31.728 -23.979 44.468 1.00 61.20 ? 341 TYR A CG 1 ATOM 2552 C CD1 . TYR A 1 340 ? -30.908 -25.018 44.916 1.00 56.27 ? 341 TYR A CD1 1 ATOM 2553 C CD2 . TYR A 1 340 ? -31.375 -22.676 44.818 1.00 57.41 ? 341 TYR A CD2 1 ATOM 2554 C CE1 . TYR A 1 340 ? -29.763 -24.765 45.673 1.00 49.72 ? 341 TYR A CE1 1 ATOM 2555 C CE2 . TYR A 1 340 ? -30.236 -22.413 45.573 1.00 55.44 ? 341 TYR A CE2 1 ATOM 2556 C CZ . TYR A 1 340 ? -29.432 -23.461 45.998 1.00 61.26 ? 341 TYR A CZ 1 ATOM 2557 O OH . TYR A 1 340 ? -28.306 -23.201 46.766 1.00 65.45 ? 341 TYR A OH 1 ATOM 2558 N N . GLY A 1 341 ? -34.188 -24.410 40.169 1.00 60.09 ? 342 GLY A N 1 ATOM 2559 C CA . GLY A 1 341 ? -35.088 -25.120 39.269 1.00 62.53 ? 342 GLY A CA 1 ATOM 2560 C C . GLY A 1 341 ? -36.030 -24.344 38.357 1.00 59.40 ? 342 GLY A C 1 ATOM 2561 O O . GLY A 1 341 ? -36.596 -24.925 37.439 1.00 68.19 ? 342 GLY A O 1 ATOM 2562 N N . ALA A 1 342 ? -36.233 -23.055 38.605 1.00 62.44 ? 343 ALA A N 1 ATOM 2563 C CA . ALA A 1 342 ? -37.071 -22.256 37.714 1.00 64.33 ? 343 ALA A CA 1 ATOM 2564 C C . ALA A 1 342 ? -36.382 -22.113 36.359 1.00 67.44 ? 343 ALA A C 1 ATOM 2565 O O . ALA A 1 342 ? -35.205 -21.733 36.286 1.00 66.23 ? 343 ALA A O 1 ATOM 2566 C CB . ALA A 1 342 ? -37.385 -20.887 38.308 1.00 52.16 ? 343 ALA A CB 1 ATOM 2567 N N . PRO A 1 343 ? -37.116 -22.433 35.280 1.00 65.19 ? 344 PRO A N 1 ATOM 2568 C CA . PRO A 1 343 ? -36.568 -22.448 33.916 1.00 59.22 ? 344 PRO A CA 1 ATOM 2569 C C . PRO A 1 343 ? -36.066 -21.072 33.525 1.00 59.76 ? 344 PRO A C 1 ATOM 2570 O O . PRO A 1 343 ? -36.797 -20.099 33.702 1.00 61.67 ? 344 PRO A O 1 ATOM 2571 C CB . PRO A 1 343 ? -37.771 -22.840 33.053 1.00 51.06 ? 344 PRO A CB 1 ATOM 2572 C CG . PRO A 1 343 ? -38.972 -22.522 33.882 1.00 68.59 ? 344 PRO A CG 1 ATOM 2573 C CD . PRO A 1 343 ? -38.555 -22.748 35.313 1.00 55.43 ? 344 PRO A CD 1 ATOM 2574 N N . GLY A 1 344 ? -34.828 -20.997 33.037 1.00 64.80 ? 345 GLY A N 1 ATOM 2575 C CA . GLY A 1 344 ? -34.239 -19.746 32.590 1.00 61.18 ? 345 GLY A CA 1 ATOM 2576 C C . GLY A 1 344 ? -33.364 -19.031 33.608 1.00 71.64 ? 345 GLY A C 1 ATOM 2577 O O . GLY A 1 344 ? -32.713 -18.033 33.284 1.00 73.09 ? 345 GLY A O 1 ATOM 2578 N N . PHE A 1 345 ? -33.343 -19.534 34.841 1.00 68.29 ? 346 PHE A N 1 ATOM 2579 C CA . PHE A 1 345 ? -32.577 -18.898 35.910 1.00 65.80 ? 346 PHE A CA 1 ATOM 2580 C C . PHE A 1 345 ? -31.224 -19.543 36.190 1.00 68.45 ? 346 PHE A C 1 ATOM 2581 O O . PHE A 1 345 ? -31.123 -20.754 36.399 1.00 71.75 ? 346 PHE A O 1 ATOM 2582 C CB . PHE A 1 345 ? -33.389 -18.851 37.197 1.00 62.74 ? 346 PHE A CB 1 ATOM 2583 C CG . PHE A 1 345 ? -34.493 -17.847 37.172 1.00 58.44 ? 346 PHE A CG 1 ATOM 2584 C CD1 . PHE A 1 345 ? -34.267 -16.545 37.588 1.00 54.60 ? 346 PHE A CD1 1 ATOM 2585 C CD2 . PHE A 1 345 ? -35.759 -18.203 36.737 1.00 56.59 ? 346 PHE A CD2 1 ATOM 2586 C CE1 . PHE A 1 345 ? -35.288 -15.609 37.582 1.00 55.69 ? 346 PHE A CE1 1 ATOM 2587 C CE2 . PHE A 1 345 ? -36.786 -17.273 36.723 1.00 56.83 ? 346 PHE A CE2 1 ATOM 2588 C CZ . PHE A 1 345 ? -36.551 -15.974 37.147 1.00 58.95 ? 346 PHE A CZ 1 ATOM 2589 N N . SER A 1 346 ? -30.196 -18.703 36.206 1.00 66.31 ? 347 SER A N 1 ATOM 2590 C CA . SER A 1 346 ? -28.840 -19.106 36.532 1.00 67.75 ? 347 SER A CA 1 ATOM 2591 C C . SER A 1 346 ? -28.158 -17.891 37.139 1.00 67.80 ? 347 SER A C 1 ATOM 2592 O O . SER A 1 346 ? -28.569 -16.755 36.884 1.00 61.71 ? 347 SER A O 1 ATOM 2593 C CB . SER A 1 346 ? -28.100 -19.545 35.267 1.00 72.24 ? 347 SER A CB 1 ATOM 2594 O OG . SER A 1 346 ? -26.759 -19.905 35.541 1.00 74.80 ? 347 SER A OG 1 ATOM 2595 N N . LYS A 1 347 ? -27.127 -18.120 37.945 1.00 68.42 ? 348 LYS A N 1 ATOM 2596 C CA . LYS A 1 347 ? -26.375 -17.007 38.521 1.00 71.98 ? 348 LYS A CA 1 ATOM 2597 C C . LYS A 1 347 ? -25.271 -16.581 37.561 1.00 71.63 ? 348 LYS A C 1 ATOM 2598 O O . LYS A 1 347 ? -24.548 -15.618 37.821 1.00 68.08 ? 348 LYS A O 1 ATOM 2599 C CB . LYS A 1 347 ? -25.789 -17.372 39.897 1.00 62.63 ? 348 LYS A CB 1 ATOM 2600 C CG . LYS A 1 347 ? -24.690 -18.416 39.873 1.00 63.15 ? 348 LYS A CG 1 ATOM 2601 C CD . LYS A 1 347 ? -23.306 -17.817 40.093 1.00 71.39 ? 348 LYS A CD 1 ATOM 2602 C CE . LYS A 1 347 ? -22.254 -18.915 40.241 1.00 73.92 ? 348 LYS A CE 1 ATOM 2603 N NZ . LYS A 1 347 ? -20.888 -18.492 39.813 1.00 72.42 ? 348 LYS A NZ 1 ATOM 2604 N N . ASP A 1 348 ? -25.158 -17.296 36.443 1.00 70.07 ? 349 ASP A N 1 ATOM 2605 C CA . ASP A 1 348 ? -24.046 -17.096 35.516 1.00 68.15 ? 349 ASP A CA 1 ATOM 2606 C C . ASP A 1 348 ? -24.421 -16.272 34.278 1.00 70.61 ? 349 ASP A C 1 ATOM 2607 O O . ASP A 1 348 ? -23.587 -16.018 33.413 1.00 68.32 ? 349 ASP A O 1 ATOM 2608 C CB . ASP A 1 348 ? -23.419 -18.438 35.141 1.00 61.27 ? 349 ASP A CB 1 ATOM 2609 C CG . ASP A 1 348 ? -22.628 -19.054 36.285 1.00 71.82 ? 349 ASP A CG 1 ATOM 2610 O OD1 . ASP A 1 348 ? -21.833 -18.323 36.920 1.00 76.34 ? 349 ASP A OD1 1 ATOM 2611 O OD2 . ASP A 1 348 ? -22.799 -20.266 36.553 1.00 72.08 ? 349 ASP A OD2 1 ATOM 2612 N N . ASN A 1 349 ? -25.685 -15.866 34.205 1.00 74.87 ? 350 ASN A N 1 ATOM 2613 C CA . ASN A 1 349 ? -26.117 -14.803 33.298 1.00 75.88 ? 350 ASN A CA 1 ATOM 2614 C C . ASN A 1 349 ? -27.221 -13.984 33.966 1.00 71.28 ? 350 ASN A C 1 ATOM 2615 O O . ASN A 1 349 ? -27.481 -14.165 35.154 1.00 71.82 ? 350 ASN A O 1 ATOM 2616 C CB . ASN A 1 349 ? -26.522 -15.331 31.909 1.00 83.22 ? 350 ASN A CB 1 ATOM 2617 C CG . ASN A 1 349 ? -27.720 -16.278 31.940 1.00 83.49 ? 350 ASN A CG 1 ATOM 2618 O OD1 . ASN A 1 349 ? -28.668 -16.105 32.715 1.00 75.70 ? 350 ASN A OD1 1 ATOM 2619 N ND2 . ASN A 1 349 ? -27.685 -17.278 31.056 1.00 91.22 ? 350 ASN A ND2 1 ATOM 2620 N N . GLU A 1 350 ? -27.872 -13.093 33.228 1.00 69.54 ? 351 GLU A N 1 ATOM 2621 C CA . GLU A 1 350 ? -28.825 -12.188 33.862 1.00 66.69 ? 351 GLU A CA 1 ATOM 2622 C C . GLU A 1 350 ? -30.246 -12.721 33.912 1.00 62.88 ? 351 GLU A C 1 ATOM 2623 O O . GLU A 1 350 ? -31.158 -11.988 34.291 1.00 60.80 ? 351 GLU A O 1 ATOM 2624 C CB . GLU A 1 350 ? -28.820 -10.829 33.184 1.00 68.96 ? 351 GLU A CB 1 ATOM 2625 C CG . GLU A 1 350 ? -27.476 -10.164 33.143 1.00 71.48 ? 351 GLU A CG 1 ATOM 2626 C CD . GLU A 1 350 ? -27.544 -8.852 32.413 1.00 83.26 ? 351 GLU A CD 1 ATOM 2627 O OE1 . GLU A 1 350 ? -28.570 -8.150 32.564 1.00 86.03 ? 351 GLU A OE1 1 ATOM 2628 O OE2 . GLU A 1 350 ? -26.588 -8.532 31.676 1.00 92.55 ? 351 GLU A OE2 1 ATOM 2629 N N . SER A 1 351 ? -30.424 -13.984 33.525 1.00 58.96 ? 352 SER A N 1 ATOM 2630 C CA . SER A 1 351 ? -31.718 -14.661 33.626 1.00 59.71 ? 352 SER A CA 1 ATOM 2631 C C . SER A 1 351 ? -32.881 -13.800 33.106 1.00 67.04 ? 352 SER A C 1 ATOM 2632 O O . SER A 1 351 ? -33.894 -13.632 33.793 1.00 63.39 ? 352 SER A O 1 ATOM 2633 C CB . SER A 1 351 ? -31.996 -15.101 35.074 1.00 67.00 ? 352 SER A CB 1 ATOM 2634 O OG . SER A 1 351 ? -30.913 -15.829 35.649 1.00 60.83 ? 352 SER A OG 1 ATOM 2635 N N . LEU A 1 352 ? -32.713 -13.250 31.903 1.00 67.16 ? 353 LEU A N 1 ATOM 2636 C CA . LEU A 1 352 ? -33.771 -12.515 31.216 1.00 69.79 ? 353 LEU A CA 1 ATOM 2637 C C . LEU A 1 352 ? -34.756 -13.488 30.574 1.00 73.41 ? 353 LEU A C 1 ATOM 2638 O O . LEU A 1 352 ? -34.635 -13.837 29.404 1.00 75.58 ? 353 LEU A O 1 ATOM 2639 C CB . LEU A 1 352 ? -33.170 -11.582 30.163 1.00 64.13 ? 353 LEU A CB 1 ATOM 2640 C CG . LEU A 1 352 ? -32.515 -10.363 30.812 1.00 73.54 ? 353 LEU A CG 1 ATOM 2641 C CD1 . LEU A 1 352 ? -31.388 -9.810 29.974 1.00 56.28 ? 353 LEU A CD1 1 ATOM 2642 C CD2 . LEU A 1 352 ? -33.570 -9.304 31.067 1.00 72.39 ? 353 LEU A CD2 1 ATOM 2643 N N . ILE A 1 353 ? -35.736 -13.920 31.352 1.00 72.30 ? 354 ILE A N 1 ATOM 2644 C CA . ILE A 1 353 ? -36.621 -14.990 30.928 1.00 68.21 ? 354 ILE A CA 1 ATOM 2645 C C . ILE A 1 353 ? -37.734 -14.530 29.990 1.00 64.41 ? 354 ILE A C 1 ATOM 2646 O O . ILE A 1 353 ? -38.117 -13.358 29.959 1.00 56.64 ? 354 ILE A O 1 ATOM 2647 C CB . ILE A 1 353 ? -37.257 -15.691 32.144 1.00 65.79 ? 354 ILE A CB 1 ATOM 2648 C CG1 . ILE A 1 353 ? -38.092 -14.697 32.953 1.00 61.81 ? 354 ILE A CG1 1 ATOM 2649 C CG2 . ILE A 1 353 ? -36.188 -16.310 33.012 1.00 66.14 ? 354 ILE A CG2 1 ATOM 2650 C CD1 . ILE A 1 353 ? -38.904 -15.337 34.043 1.00 62.95 ? 354 ILE A CD1 1 ATOM 2651 N N . SER A 1 354 ? -38.254 -15.489 29.233 1.00 67.40 ? 355 SER A N 1 ATOM 2652 C CA . SER A 1 354 ? -39.370 -15.257 28.334 1.00 66.58 ? 355 SER A CA 1 ATOM 2653 C C . SER A 1 354 ? -40.635 -15.360 29.149 1.00 65.46 ? 355 SER A C 1 ATOM 2654 O O . SER A 1 354 ? -40.597 -15.804 30.288 1.00 74.83 ? 355 SER A O 1 ATOM 2655 C CB . SER A 1 354 ? -39.417 -16.347 27.282 1.00 63.91 ? 355 SER A CB 1 ATOM 2656 O OG . SER A 1 354 ? -40.031 -17.499 27.835 1.00 67.93 ? 355 SER A OG 1 ATOM 2657 N N . ARG A 1 355 ? -41.762 -14.978 28.563 1.00 64.36 ? 356 ARG A N 1 ATOM 2658 C CA . ARG A 1 355 ? -43.029 -15.090 29.256 1.00 61.33 ? 356 ARG A CA 1 ATOM 2659 C C . ARG A 1 355 ? -43.397 -16.556 29.418 1.00 62.65 ? 356 ARG A C 1 ATOM 2660 O O . ARG A 1 355 ? -44.036 -16.950 30.395 1.00 68.18 ? 356 ARG A O 1 ATOM 2661 C CB . ARG A 1 355 ? -44.133 -14.320 28.541 1.00 55.23 ? 356 ARG A CB 1 ATOM 2662 C CG . ARG A 1 355 ? -45.495 -14.565 29.141 1.00 55.94 ? 356 ARG A CG 1 ATOM 2663 C CD . ARG A 1 355 ? -46.365 -13.356 29.061 1.00 57.94 ? 356 ARG A CD 1 ATOM 2664 N NE . ARG A 1 355 ? -47.602 -13.569 29.805 1.00 69.61 ? 356 ARG A NE 1 ATOM 2665 C CZ . ARG A 1 355 ? -47.845 -13.087 31.021 1.00 65.64 ? 356 ARG A CZ 1 ATOM 2666 N NH1 . ARG A 1 355 ? -46.936 -12.341 31.637 1.00 64.33 ? 356 ARG A NH1 1 ATOM 2667 N NH2 . ARG A 1 355 ? -49.007 -13.344 31.613 1.00 61.06 ? 356 ARG A NH2 1 ATOM 2668 N N . ALA A 1 356 ? -42.959 -17.375 28.476 1.00 60.61 ? 357 ALA A N 1 ATOM 2669 C CA . ALA A 1 356 ? -43.244 -18.801 28.545 1.00 65.30 ? 357 ALA A CA 1 ATOM 2670 C C . ALA A 1 356 ? -42.532 -19.425 29.742 1.00 62.98 ? 357 ALA A C 1 ATOM 2671 O O . ALA A 1 356 ? -43.085 -20.295 30.412 1.00 65.38 ? 357 ALA A O 1 ATOM 2672 C CB . ALA A 1 356 ? -42.844 -19.495 27.256 1.00 50.81 ? 357 ALA A CB 1 ATOM 2673 N N . GLU A 1 357 ? -41.307 -18.978 30.001 1.00 61.76 ? 358 GLU A N 1 ATOM 2674 C CA . GLU A 1 357 ? -40.560 -19.423 31.185 1.00 70.53 ? 358 GLU A CA 1 ATOM 2675 C C . GLU A 1 357 ? -41.214 -18.927 32.484 1.00 62.08 ? 358 GLU A C 1 ATOM 2676 O O . GLU A 1 357 ? -41.423 -19.696 33.414 1.00 60.26 ? 358 GLU A O 1 ATOM 2677 C CB . GLU A 1 357 ? -39.089 -18.986 31.094 1.00 65.89 ? 358 GLU A CB 1 ATOM 2678 C CG . GLU A 1 357 ? -38.256 -19.846 30.142 1.00 59.97 ? 358 GLU A CG 1 ATOM 2679 C CD . GLU A 1 357 ? -36.939 -19.203 29.759 1.00 67.27 ? 358 GLU A CD 1 ATOM 2680 O OE1 . GLU A 1 357 ? -36.901 -17.953 29.640 1.00 67.56 ? 358 GLU A OE1 1 ATOM 2681 O OE2 . GLU A 1 357 ? -35.945 -19.950 29.577 1.00 60.47 ? 358 GLU A OE2 1 ATOM 2682 N N . PHE A 1 358 ? -41.557 -17.644 32.514 1.00 60.80 ? 359 PHE A N 1 ATOM 2683 C CA . PHE A 1 358 ? -42.332 -17.072 33.602 1.00 60.44 ? 359 PHE A CA 1 ATOM 2684 C C . PHE A 1 358 ? -43.539 -17.914 34.029 1.00 62.42 ? 359 PHE A C 1 ATOM 2685 O O . PHE A 1 358 ? -43.707 -18.202 35.209 1.00 70.79 ? 359 PHE A O 1 ATOM 2686 C CB . PHE A 1 358 ? -42.808 -15.670 33.239 1.00 59.76 ? 359 PHE A CB 1 ATOM 2687 C CG . PHE A 1 358 ? -43.671 -15.059 34.284 1.00 58.23 ? 359 PHE A CG 1 ATOM 2688 C CD1 . PHE A 1 358 ? -43.120 -14.654 35.505 1.00 58.07 ? 359 PHE A CD1 1 ATOM 2689 C CD2 . PHE A 1 358 ? -45.033 -14.907 34.075 1.00 55.21 ? 359 PHE A CD2 1 ATOM 2690 C CE1 . PHE A 1 358 ? -43.918 -14.096 36.506 1.00 52.83 ? 359 PHE A CE1 1 ATOM 2691 C CE2 . PHE A 1 358 ? -45.847 -14.340 35.072 1.00 61.77 ? 359 PHE A CE2 1 ATOM 2692 C CZ . PHE A 1 358 ? -45.282 -13.937 36.294 1.00 57.42 ? 359 PHE A CZ 1 ATOM 2693 N N . LEU A 1 359 ? -44.381 -18.297 33.077 1.00 62.85 ? 360 LEU A N 1 ATOM 2694 C CA . LEU A 1 359 ? -45.583 -19.066 33.386 1.00 61.05 ? 360 LEU A CA 1 ATOM 2695 C C . LEU A 1 359 ? -45.265 -20.466 33.915 1.00 59.48 ? 360 LEU A C 1 ATOM 2696 O O . LEU A 1 359 ? -45.984 -21.004 34.765 1.00 60.41 ? 360 LEU A O 1 ATOM 2697 C CB . LEU A 1 359 ? -46.488 -19.160 32.149 1.00 59.78 ? 360 LEU A CB 1 ATOM 2698 C CG . LEU A 1 359 ? -47.001 -17.839 31.579 1.00 62.95 ? 360 LEU A CG 1 ATOM 2699 C CD1 . LEU A 1 359 ? -47.627 -18.043 30.199 1.00 56.21 ? 360 LEU A CD1 1 ATOM 2700 C CD2 . LEU A 1 359 ? -47.988 -17.190 32.532 1.00 58.64 ? 360 LEU A CD2 1 ATOM 2701 N N . ALA A 1 360 ? -44.197 -21.062 33.398 1.00 60.55 ? 361 ALA A N 1 ATOM 2702 C CA . ALA A 1 360 ? -43.775 -22.381 33.851 1.00 60.21 ? 361 ALA A CA 1 ATOM 2703 C C . ALA A 1 360 ? -43.172 -22.289 35.253 1.00 66.01 ? 361 ALA A C 1 ATOM 2704 O O . ALA A 1 360 ? -43.293 -23.223 36.056 1.00 68.33 ? 361 ALA A O 1 ATOM 2705 C CB . ALA A 1 360 ? -42.776 -22.955 32.905 1.00 45.60 ? 361 ALA A CB 1 ATOM 2706 N N . GLY A 1 361 ? -42.520 -21.155 35.524 1.00 59.29 ? 362 GLY A N 1 ATOM 2707 C CA . GLY A 1 361 ? -41.872 -20.894 36.798 1.00 65.28 ? 362 GLY A CA 1 ATOM 2708 C C . GLY A 1 361 ? -42.878 -20.651 37.902 1.00 67.24 ? 362 GLY A C 1 ATOM 2709 O O . GLY A 1 361 ? -42.608 -20.953 39.057 1.00 65.09 ? 362 GLY A O 1 ATOM 2710 N N . VAL A 1 362 ? -44.046 -20.117 37.545 1.00 64.45 ? 363 VAL A N 1 ATOM 2711 C CA . VAL A 1 362 ? -45.108 -19.905 38.517 1.00 59.46 ? 363 VAL A CA 1 ATOM 2712 C C . VAL A 1 362 ? -45.523 -21.230 39.130 1.00 62.82 ? 363 VAL A C 1 ATOM 2713 O O . VAL A 1 362 ? -45.683 -21.327 40.342 1.00 65.95 ? 363 VAL A O 1 ATOM 2714 C CB . VAL A 1 362 ? -46.331 -19.201 37.901 1.00 58.31 ? 363 VAL A CB 1 ATOM 2715 C CG1 . VAL A 1 362 ? -47.548 -19.347 38.802 1.00 55.34 ? 363 VAL A CG1 1 ATOM 2716 C CG2 . VAL A 1 362 ? -46.023 -17.729 37.642 1.00 55.74 ? 363 VAL A CG2 1 ATOM 2717 N N . ARG A 1 363 ? -45.667 -22.262 38.308 1.00 62.09 ? 364 ARG A N 1 ATOM 2718 C CA . ARG A 1 363 ? -46.028 -23.582 38.831 1.00 66.40 ? 364 ARG A CA 1 ATOM 2719 C C . ARG A 1 363 ? -44.975 -24.141 39.792 1.00 67.74 ? 364 ARG A C 1 ATOM 2720 O O . ARG A 1 363 ? -45.300 -24.901 40.705 1.00 75.02 ? 364 ARG A O 1 ATOM 2721 C CB . ARG A 1 363 ? -46.273 -24.577 37.696 1.00 68.29 ? 364 ARG A CB 1 ATOM 2722 C CG . ARG A 1 363 ? -47.295 -24.123 36.678 1.00 75.85 ? 364 ARG A CG 1 ATOM 2723 C CD . ARG A 1 363 ? -48.511 -23.490 37.342 1.00 79.47 ? 364 ARG A CD 1 ATOM 2724 N NE . ARG A 1 363 ? -49.241 -24.390 38.238 1.00 79.91 ? 364 ARG A NE 1 ATOM 2725 C CZ . ARG A 1 363 ? -50.298 -25.119 37.884 1.00 87.73 ? 364 ARG A CZ 1 ATOM 2726 N NH1 . ARG A 1 363 ? -50.759 -25.082 36.631 1.00 80.66 ? 364 ARG A NH1 1 ATOM 2727 N NH2 . ARG A 1 363 ? -50.893 -25.891 38.790 1.00 82.30 ? 364 ARG A NH2 1 ATOM 2728 N N . VAL A 1 364 ? -43.717 -23.761 39.578 1.00 68.10 ? 365 VAL A N 1 ATOM 2729 C CA . VAL A 1 364 ? -42.610 -24.221 40.410 1.00 63.29 ? 365 VAL A CA 1 ATOM 2730 C C . VAL A 1 364 ? -42.546 -23.465 41.751 1.00 68.24 ? 365 VAL A C 1 ATOM 2731 O O . VAL A 1 364 ? -42.411 -24.078 42.815 1.00 74.73 ? 365 VAL A O 1 ATOM 2732 C CB . VAL A 1 364 ? -41.264 -24.104 39.654 1.00 67.48 ? 365 VAL A CB 1 ATOM 2733 C CG1 . VAL A 1 364 ? -40.117 -24.427 40.564 1.00 62.96 ? 365 VAL A CG1 1 ATOM 2734 C CG2 . VAL A 1 364 ? -41.240 -25.029 38.440 1.00 61.94 ? 365 VAL A CG2 1 ATOM 2735 N N . GLY A 1 365 ? -42.665 -22.141 41.708 1.00 66.64 ? 366 GLY A N 1 ATOM 2736 C CA . GLY A 1 365 ? -42.660 -21.336 42.924 1.00 58.38 ? 366 GLY A CA 1 ATOM 2737 C C . GLY A 1 365 ? -43.967 -21.280 43.707 1.00 58.40 ? 366 GLY A C 1 ATOM 2738 O O . GLY A 1 365 ? -44.061 -20.581 44.705 1.00 69.59 ? 366 GLY A O 1 ATOM 2739 N N . VAL A 1 366 ? -44.992 -21.985 43.247 1.00 65.36 ? 367 VAL A N 1 ATOM 2740 C CA . VAL A 1 366 ? -46.250 -22.101 43.984 1.00 62.91 ? 367 VAL A CA 1 ATOM 2741 C C . VAL A 1 366 ? -46.753 -23.526 43.805 1.00 63.27 ? 367 VAL A C 1 ATOM 2742 O O . VAL A 1 366 ? -47.598 -23.795 42.955 1.00 70.42 ? 367 VAL A O 1 ATOM 2743 C CB . VAL A 1 366 ? -47.342 -21.118 43.489 1.00 56.78 ? 367 VAL A CB 1 ATOM 2744 C CG1 . VAL A 1 366 ? -48.604 -21.243 44.349 1.00 53.39 ? 367 VAL A CG1 1 ATOM 2745 C CG2 . VAL A 1 366 ? -46.839 -19.685 43.487 1.00 49.22 ? 367 VAL A CG2 1 ATOM 2746 N N . PRO A 1 367 ? -46.223 -24.448 44.612 1.00 64.37 ? 368 PRO A N 1 ATOM 2747 C CA . PRO A 1 367 ? -46.480 -25.881 44.473 1.00 63.60 ? 368 PRO A CA 1 ATOM 2748 C C . PRO A 1 367 ? -47.876 -26.207 44.938 1.00 67.32 ? 368 PRO A C 1 ATOM 2749 O O . PRO A 1 367 ? -48.432 -25.435 45.716 1.00 70.86 ? 368 PRO A O 1 ATOM 2750 C CB . PRO A 1 367 ? -45.472 -26.508 45.428 1.00 65.78 ? 368 PRO A CB 1 ATOM 2751 C CG . PRO A 1 367 ? -44.625 -25.359 45.950 1.00 64.50 ? 368 PRO A CG 1 ATOM 2752 C CD . PRO A 1 367 ? -45.433 -24.147 45.810 1.00 52.79 ? 368 PRO A CD 1 ATOM 2753 N N . GLN A 1 368 ? -48.440 -27.310 44.456 1.00 75.56 ? 369 GLN A N 1 ATOM 2754 C CA . GLN A 1 368 ? -49.728 -27.797 44.963 1.00 88.82 ? 369 GLN A CA 1 ATOM 2755 C C . GLN A 1 368 ? -50.857 -26.759 44.913 1.00 86.81 ? 369 GLN A C 1 ATOM 2756 O O . GLN A 1 368 ? -51.346 -26.327 45.959 1.00 80.34 ? 369 GLN A O 1 ATOM 2757 C CB . GLN A 1 368 ? -49.584 -28.318 46.410 1.00 83.80 ? 369 GLN A CB 1 ATOM 2758 C CG . GLN A 1 368 ? -49.289 -29.818 46.544 1.00 88.11 ? 369 GLN A CG 1 ATOM 2759 C CD . GLN A 1 368 ? -47.807 -30.141 46.748 1.00 95.27 ? 369 GLN A CD 1 ATOM 2760 O OE1 . GLN A 1 368 ? -46.989 -29.253 46.985 1.00 96.33 ? 369 GLN A OE1 1 ATOM 2761 N NE2 . GLN A 1 368 ? -47.464 -31.425 46.664 1.00 92.93 ? 369 GLN A NE2 1 ATOM 2762 N N . VAL A 1 369 ? -51.262 -26.358 43.709 1.00 85.00 ? 370 VAL A N 1 ATOM 2763 C CA . VAL A 1 369 ? -52.442 -25.503 43.543 1.00 83.94 ? 370 VAL A CA 1 ATOM 2764 C C . VAL A 1 369 ? -53.156 -25.851 42.249 1.00 86.00 ? 370 VAL A C 1 ATOM 2765 O O . VAL A 1 369 ? -52.539 -26.375 41.321 1.00 88.65 ? 370 VAL A O 1 ATOM 2766 C CB . VAL A 1 369 ? -52.090 -23.992 43.531 1.00 85.80 ? 370 VAL A CB 1 ATOM 2767 C CG1 . VAL A 1 369 ? -51.893 -23.451 44.966 1.00 79.76 ? 370 VAL A CG1 1 ATOM 2768 C CG2 . VAL A 1 369 ? -50.871 -23.726 42.640 1.00 74.83 ? 370 VAL A CG2 1 ATOM 2769 N N . SER A 1 370 ? -54.453 -25.560 42.183 1.00 87.33 ? 371 SER A N 1 ATOM 2770 C CA . SER A 1 370 ? -55.225 -25.787 40.958 1.00 76.71 ? 371 SER A CA 1 ATOM 2771 C C . SER A 1 370 ? -54.663 -24.956 39.816 1.00 77.94 ? 371 SER A C 1 ATOM 2772 O O . SER A 1 370 ? -53.936 -23.983 40.048 1.00 77.87 ? 371 SER A O 1 ATOM 2773 C CB . SER A 1 370 ? -56.693 -25.418 41.177 1.00 78.57 ? 371 SER A CB 1 ATOM 2774 O OG . SER A 1 370 ? -56.843 -24.037 41.465 1.00 73.53 ? 371 SER A OG 1 ATOM 2775 N N . ASP A 1 371 ? -55.000 -25.334 38.584 1.00 82.39 ? 372 ASP A N 1 ATOM 2776 C CA . ASP A 1 371 ? -54.626 -24.539 37.414 1.00 72.49 ? 372 ASP A CA 1 ATOM 2777 C C . ASP A 1 371 ? -55.256 -23.157 37.493 1.00 67.24 ? 372 ASP A C 1 ATOM 2778 O O . ASP A 1 371 ? -54.651 -22.168 37.077 1.00 66.19 ? 372 ASP A O 1 ATOM 2779 C CB . ASP A 1 371 ? -55.057 -25.225 36.118 1.00 81.58 ? 372 ASP A CB 1 ATOM 2780 C CG . ASP A 1 371 ? -54.222 -26.448 35.798 1.00 91.88 ? 372 ASP A CG 1 ATOM 2781 O OD1 . ASP A 1 371 ? -53.703 -27.082 36.749 1.00 88.10 ? 372 ASP A OD1 1 ATOM 2782 O OD2 . ASP A 1 371 ? -54.092 -26.771 34.592 1.00 90.38 ? 372 ASP A OD2 1 ATOM 2783 N N . LEU A 1 372 ? -56.471 -23.105 38.035 1.00 66.86 ? 373 LEU A N 1 ATOM 2784 C CA . LEU A 1 372 ? -57.169 -21.847 38.278 1.00 63.91 ? 373 LEU A CA 1 ATOM 2785 C C . LEU A 1 372 ? -56.374 -20.932 39.212 1.00 70.43 ? 373 LEU A C 1 ATOM 2786 O O . LEU A 1 372 ? -56.188 -19.754 38.904 1.00 68.64 ? 373 LEU A O 1 ATOM 2787 C CB . LEU A 1 372 ? -58.578 -22.101 38.836 1.00 61.09 ? 373 LEU A CB 1 ATOM 2788 C CG . LEU A 1 372 ? -59.483 -20.882 39.059 1.00 65.52 ? 373 LEU A CG 1 ATOM 2789 C CD1 . LEU A 1 372 ? -59.733 -20.140 37.755 1.00 64.35 ? 373 LEU A CD1 1 ATOM 2790 C CD2 . LEU A 1 372 ? -60.804 -21.268 39.713 1.00 68.10 ? 373 LEU A CD2 1 ATOM 2791 N N . ALA A 1 373 ? -55.901 -21.470 40.341 1.00 75.01 ? 374 ALA A N 1 ATOM 2792 C CA . ALA A 1 373 ? -55.102 -20.680 41.290 1.00 66.31 ? 374 ALA A CA 1 ATOM 2793 C C . ALA A 1 373 ? -53.840 -20.100 40.634 1.00 63.24 ? 374 ALA A C 1 ATOM 2794 O O . ALA A 1 373 ? -53.489 -18.946 40.869 1.00 55.99 ? 374 ALA A O 1 ATOM 2795 C CB . ALA A 1 373 ? -54.743 -21.504 42.515 1.00 60.17 ? 374 ALA A CB 1 ATOM 2796 N N . ALA A 1 374 ? -53.167 -20.892 39.802 1.00 56.75 ? 375 ALA A N 1 ATOM 2797 C CA . ALA A 1 374 ? -52.013 -20.373 39.071 1.00 63.17 ? 375 ALA A CA 1 ATOM 2798 C C . ALA A 1 374 ? -52.366 -19.216 38.124 1.00 67.36 ? 375 ALA A C 1 ATOM 2799 O O . ALA A 1 374 ? -51.550 -18.317 37.920 1.00 67.69 ? 375 ALA A O 1 ATOM 2800 C CB . ALA A 1 374 ? -51.291 -21.480 38.319 1.00 59.93 ? 375 ALA A CB 1 ATOM 2801 N N . GLU A 1 375 ? -53.570 -19.227 37.548 1.00 67.16 ? 376 GLU A N 1 ATOM 2802 C CA . GLU A 1 375 ? -53.975 -18.143 36.639 1.00 64.22 ? 376 GLU A CA 1 ATOM 2803 C C . GLU A 1 375 ? -54.208 -16.853 37.423 1.00 60.72 ? 376 GLU A C 1 ATOM 2804 O O . GLU A 1 375 ? -53.961 -15.742 36.924 1.00 52.04 ? 376 GLU A O 1 ATOM 2805 C CB . GLU A 1 375 ? -55.213 -18.526 35.801 1.00 69.35 ? 376 GLU A CB 1 ATOM 2806 C CG . GLU A 1 375 ? -54.914 -19.427 34.578 1.00 65.98 ? 376 GLU A CG 1 ATOM 2807 C CD . GLU A 1 375 ? -53.899 -18.811 33.610 1.00 78.00 ? 376 GLU A CD 1 ATOM 2808 O OE1 . GLU A 1 375 ? -54.123 -17.668 33.133 1.00 79.63 ? 376 GLU A OE1 1 ATOM 2809 O OE2 . GLU A 1 375 ? -52.869 -19.468 33.333 1.00 77.93 ? 376 GLU A OE2 1 ATOM 2810 N N . ALA A 1 376 ? -54.662 -17.020 38.665 1.00 59.71 ? 377 ALA A N 1 ATOM 2811 C CA . ALA A 1 376 ? -54.866 -15.903 39.577 1.00 54.23 ? 377 ALA A CA 1 ATOM 2812 C C . ALA A 1 376 ? -53.534 -15.241 39.935 1.00 56.00 ? 377 ALA A C 1 ATOM 2813 O O . ALA A 1 376 ? -53.465 -14.019 40.123 1.00 50.91 ? 377 ALA A O 1 ATOM 2814 C CB . ALA A 1 376 ? -55.582 -16.371 40.831 1.00 58.94 ? 377 ALA A CB 1 ATOM 2815 N N . VAL A 1 377 ? -52.475 -16.046 40.016 1.00 51.69 ? 378 VAL A N 1 ATOM 2816 C CA . VAL A 1 377 ? -51.172 -15.519 40.404 1.00 57.35 ? 378 VAL A CA 1 ATOM 2817 C C . VAL A 1 377 ? -50.642 -14.710 39.244 1.00 56.43 ? 378 VAL A C 1 ATOM 2818 O O . VAL A 1 377 ? -50.283 -13.531 39.395 1.00 52.75 ? 378 VAL A O 1 ATOM 2819 C CB . VAL A 1 377 ? -50.163 -16.636 40.792 1.00 58.35 ? 378 VAL A CB 1 ATOM 2820 C CG1 . VAL A 1 377 ? -48.797 -16.036 41.075 1.00 50.78 ? 378 VAL A CG1 1 ATOM 2821 C CG2 . VAL A 1 377 ? -50.669 -17.424 42.014 1.00 55.21 ? 378 VAL A CG2 1 ATOM 2822 N N . VAL A 1 378 ? -50.626 -15.360 38.082 1.00 56.99 ? 379 VAL A N 1 ATOM 2823 C CA . VAL A 1 378 ? -50.294 -14.720 36.825 1.00 50.85 ? 379 VAL A CA 1 ATOM 2824 C C . VAL A 1 378 ? -51.057 -13.418 36.631 1.00 50.94 ? 379 VAL A C 1 ATOM 2825 O O . VAL A 1 378 ? -50.465 -12.409 36.242 1.00 56.42 ? 379 VAL A O 1 ATOM 2826 C CB . VAL A 1 378 ? -50.600 -15.638 35.654 1.00 59.26 ? 379 VAL A CB 1 ATOM 2827 C CG1 . VAL A 1 378 ? -50.296 -14.916 34.339 1.00 58.40 ? 379 VAL A CG1 1 ATOM 2828 C CG2 . VAL A 1 378 ? -49.800 -16.937 35.778 1.00 50.80 ? 379 VAL A CG2 1 ATOM 2829 N N . LEU A 1 379 ? -52.361 -13.434 36.904 1.00 39.89 ? 380 LEU A N 1 ATOM 2830 C CA . LEU A 1 379 ? -53.147 -12.209 36.823 1.00 45.99 ? 380 LEU A CA 1 ATOM 2831 C C . LEU A 1 379 ? -52.508 -11.092 37.629 1.00 55.40 ? 380 LEU A C 1 ATOM 2832 O O . LEU A 1 379 ? -52.172 -10.039 37.076 1.00 51.35 ? 380 LEU A O 1 ATOM 2833 C CB . LEU A 1 379 ? -54.582 -12.415 37.307 1.00 48.33 ? 380 LEU A CB 1 ATOM 2834 C CG . LEU A 1 379 ? -55.381 -11.103 37.321 1.00 48.50 ? 380 LEU A CG 1 ATOM 2835 C CD1 . LEU A 1 379 ? -55.743 -10.679 35.891 1.00 56.32 ? 380 LEU A CD1 1 ATOM 2836 C CD2 . LEU A 1 379 ? -56.639 -11.193 38.161 1.00 47.49 ? 380 LEU A CD2 1 ATOM 2837 N N . HIS A 1 380 ? -52.322 -11.345 38.933 1.00 60.74 ? 381 HIS A N 1 ATOM 2838 C CA . HIS A 1 380 ? -51.862 -10.326 39.878 1.00 46.41 ? 381 HIS A CA 1 ATOM 2839 C C . HIS A 1 380 ? -50.429 -9.856 39.585 1.00 49.08 ? 381 HIS A C 1 ATOM 2840 O O . HIS A 1 380 ? -50.120 -8.679 39.731 1.00 47.32 ? 381 HIS A O 1 ATOM 2841 C CB . HIS A 1 380 ? -52.003 -10.807 41.337 1.00 54.10 ? 381 HIS A CB 1 ATOM 2842 C CG . HIS A 1 380 ? -51.648 -9.756 42.342 1.00 55.68 ? 381 HIS A CG 1 ATOM 2843 N ND1 . HIS A 1 380 ? -50.343 -9.385 42.599 1.00 53.04 ? 381 HIS A ND1 1 ATOM 2844 C CD2 . HIS A 1 380 ? -52.427 -8.955 43.110 1.00 48.78 ? 381 HIS A CD2 1 ATOM 2845 C CE1 . HIS A 1 380 ? -50.331 -8.401 43.482 1.00 49.79 ? 381 HIS A CE1 1 ATOM 2846 N NE2 . HIS A 1 380 ? -51.582 -8.121 43.808 1.00 54.67 ? 381 HIS A NE2 1 ATOM 2847 N N . TYR A 1 381 ? -49.560 -10.765 39.153 1.00 53.12 ? 382 TYR A N 1 ATOM 2848 C CA . TYR A 1 381 ? -48.132 -10.437 38.992 1.00 53.71 ? 382 TYR A CA 1 ATOM 2849 C C . TYR A 1 381 ? -47.681 -10.043 37.581 1.00 59.17 ? 382 TYR A C 1 ATOM 2850 O O . TYR A 1 381 ? -46.496 -9.798 37.357 1.00 65.38 ? 382 TYR A O 1 ATOM 2851 C CB . TYR A 1 381 ? -47.248 -11.586 39.510 1.00 55.19 ? 382 TYR A CB 1 ATOM 2852 C CG . TYR A 1 381 ? -47.221 -11.692 41.012 1.00 55.30 ? 382 TYR A CG 1 ATOM 2853 C CD1 . TYR A 1 381 ? -46.292 -10.978 41.761 1.00 53.50 ? 382 TYR A CD1 1 ATOM 2854 C CD2 . TYR A 1 381 ? -48.145 -12.484 41.688 1.00 58.62 ? 382 TYR A CD2 1 ATOM 2855 C CE1 . TYR A 1 381 ? -46.276 -11.055 43.134 1.00 60.22 ? 382 TYR A CE1 1 ATOM 2856 C CE2 . TYR A 1 381 ? -48.136 -12.569 43.064 1.00 57.75 ? 382 TYR A CE2 1 ATOM 2857 C CZ . TYR A 1 381 ? -47.200 -11.857 43.782 1.00 57.02 ? 382 TYR A CZ 1 ATOM 2858 O OH . TYR A 1 381 ? -47.184 -11.946 45.150 1.00 60.27 ? 382 TYR A OH 1 ATOM 2859 N N . THR A 1 382 ? -48.608 -9.998 36.629 1.00 59.42 ? 383 THR A N 1 ATOM 2860 C CA . THR A 1 382 ? -48.287 -9.479 35.301 1.00 55.15 ? 383 THR A CA 1 ATOM 2861 C C . THR A 1 382 ? -48.547 -7.973 35.221 1.00 52.87 ? 383 THR A C 1 ATOM 2862 O O . THR A 1 382 ? -49.588 -7.491 35.660 1.00 54.03 ? 383 THR A O 1 ATOM 2863 C CB . THR A 1 382 ? -49.093 -10.200 34.206 1.00 61.02 ? 383 THR A CB 1 ATOM 2864 O OG1 . THR A 1 382 ? -48.873 -11.615 34.295 1.00 60.14 ? 383 THR A OG1 1 ATOM 2865 C CG2 . THR A 1 382 ? -48.689 -9.703 32.814 1.00 64.23 ? 383 THR A CG2 1 ATOM 2866 N N . ASP A 1 383 ? -47.589 -7.224 34.693 1.00 57.07 ? 384 ASP A N 1 ATOM 2867 C CA . ASP A 1 383 ? -47.859 -5.848 34.290 1.00 64.17 ? 384 ASP A CA 1 ATOM 2868 C C . ASP A 1 383 ? -48.458 -5.916 32.877 1.00 65.75 ? 384 ASP A C 1 ATOM 2869 O O . ASP A 1 383 ? -47.772 -6.287 31.925 1.00 61.43 ? 384 ASP A O 1 ATOM 2870 C CB . ASP A 1 383 ? -46.570 -5.024 34.268 1.00 60.48 ? 384 ASP A CB 1 ATOM 2871 C CG . ASP A 1 383 ? -46.826 -3.527 34.163 1.00 67.90 ? 384 ASP A CG 1 ATOM 2872 O OD1 . ASP A 1 383 ? -47.997 -3.123 33.964 1.00 65.68 ? 384 ASP A OD1 1 ATOM 2873 O OD2 . ASP A 1 383 ? -45.847 -2.754 34.279 1.00 72.59 ? 384 ASP A OD2 1 ATOM 2874 N N . TRP A 1 384 ? -49.737 -5.580 32.741 1.00 63.37 ? 385 TRP A N 1 ATOM 2875 C CA . TRP A 1 384 ? -50.398 -5.733 31.449 1.00 68.86 ? 385 TRP A CA 1 ATOM 2876 C C . TRP A 1 384 ? -50.053 -4.635 30.427 1.00 68.36 ? 385 TRP A C 1 ATOM 2877 O O . TRP A 1 384 ? -50.334 -4.786 29.242 1.00 66.27 ? 385 TRP A O 1 ATOM 2878 C CB . TRP A 1 384 ? -51.902 -5.985 31.613 1.00 57.61 ? 385 TRP A CB 1 ATOM 2879 C CG . TRP A 1 384 ? -52.152 -7.253 32.399 1.00 66.26 ? 385 TRP A CG 1 ATOM 2880 C CD1 . TRP A 1 384 ? -52.438 -7.352 33.744 1.00 53.40 ? 385 TRP A CD1 1 ATOM 2881 C CD2 . TRP A 1 384 ? -52.090 -8.605 31.906 1.00 60.77 ? 385 TRP A CD2 1 ATOM 2882 N NE1 . TRP A 1 384 ? -52.577 -8.673 34.100 1.00 48.61 ? 385 TRP A NE1 1 ATOM 2883 C CE2 . TRP A 1 384 ? -52.366 -9.462 32.999 1.00 62.95 ? 385 TRP A CE2 1 ATOM 2884 C CE3 . TRP A 1 384 ? -51.826 -9.172 30.656 1.00 58.59 ? 385 TRP A CE3 1 ATOM 2885 C CZ2 . TRP A 1 384 ? -52.397 -10.855 32.870 1.00 61.63 ? 385 TRP A CZ2 1 ATOM 2886 C CZ3 . TRP A 1 384 ? -51.861 -10.552 30.528 1.00 58.46 ? 385 TRP A CZ3 1 ATOM 2887 C CH2 . TRP A 1 384 ? -52.144 -11.379 31.629 1.00 62.13 ? 385 TRP A CH2 1 ATOM 2888 N N . LEU A 1 385 ? -49.401 -3.566 30.879 1.00 68.20 ? 386 LEU A N 1 ATOM 2889 C CA . LEU A 1 385 ? -48.745 -2.645 29.947 1.00 72.21 ? 386 LEU A CA 1 ATOM 2890 C C . LEU A 1 385 ? -47.445 -3.223 29.375 1.00 74.74 ? 386 LEU A C 1 ATOM 2891 O O . LEU A 1 385 ? -47.058 -2.886 28.256 1.00 77.18 ? 386 LEU A O 1 ATOM 2892 C CB . LEU A 1 385 ? -48.477 -1.278 30.587 1.00 71.45 ? 386 LEU A CB 1 ATOM 2893 C CG . LEU A 1 385 ? -49.694 -0.353 30.621 1.00 75.32 ? 386 LEU A CG 1 ATOM 2894 C CD1 . LEU A 1 385 ? -49.345 1.029 31.152 1.00 72.07 ? 386 LEU A CD1 1 ATOM 2895 C CD2 . LEU A 1 385 ? -50.281 -0.264 29.223 1.00 80.00 ? 386 LEU A CD2 1 ATOM 2896 N N . HIS A 1 386 ? -46.772 -4.085 30.137 1.00 74.09 ? 387 HIS A N 1 ATOM 2897 C CA . HIS A 1 386 ? -45.520 -4.683 29.665 1.00 67.48 ? 387 HIS A CA 1 ATOM 2898 C C . HIS A 1 386 ? -45.434 -6.199 29.831 1.00 65.60 ? 387 HIS A C 1 ATOM 2899 O O . HIS A 1 386 ? -44.429 -6.700 30.331 1.00 59.65 ? 387 HIS A O 1 ATOM 2900 C CB . HIS A 1 386 ? -44.320 -4.037 30.355 1.00 65.03 ? 387 HIS A CB 1 ATOM 2901 C CG . HIS A 1 386 ? -44.254 -2.552 30.188 1.00 73.19 ? 387 HIS A CG 1 ATOM 2902 N ND1 . HIS A 1 386 ? -44.830 -1.677 31.084 1.00 74.96 ? 387 HIS A ND1 1 ATOM 2903 C CD2 . HIS A 1 386 ? -43.675 -1.787 29.234 1.00 66.81 ? 387 HIS A CD2 1 ATOM 2904 C CE1 . HIS A 1 386 ? -44.605 -0.436 30.691 1.00 77.63 ? 387 HIS A CE1 1 ATOM 2905 N NE2 . HIS A 1 386 ? -43.907 -0.476 29.570 1.00 77.41 ? 387 HIS A NE2 1 ATOM 2906 N N . PRO A 1 387 ? -46.443 -6.932 29.328 1.00 66.13 ? 388 PRO A N 1 ATOM 2907 C CA . PRO A 1 387 ? -46.674 -8.352 29.623 1.00 61.20 ? 388 PRO A CA 1 ATOM 2908 C C . PRO A 1 387 ? -45.509 -9.275 29.285 1.00 59.36 ? 388 PRO A C 1 ATOM 2909 O O . PRO A 1 387 ? -45.504 -10.419 29.728 1.00 64.58 ? 388 PRO A O 1 ATOM 2910 C CB . PRO A 1 387 ? -47.857 -8.706 28.706 1.00 68.29 ? 388 PRO A CB 1 ATOM 2911 C CG . PRO A 1 387 ? -48.457 -7.404 28.305 1.00 60.83 ? 388 PRO A CG 1 ATOM 2912 C CD . PRO A 1 387 ? -47.300 -6.474 28.224 1.00 63.54 ? 388 PRO A CD 1 ATOM 2913 N N . GLU A 1 388 ? -44.545 -8.796 28.513 1.00 68.05 ? 389 GLU A N 1 ATOM 2914 C CA . GLU A 1 388 ? -43.541 -9.678 27.919 1.00 68.33 ? 389 GLU A CA 1 ATOM 2915 C C . GLU A 1 388 ? -42.119 -9.234 28.207 1.00 59.72 ? 389 GLU A C 1 ATOM 2916 O O . GLU A 1 388 ? -41.178 -9.882 27.764 1.00 57.91 ? 389 GLU A O 1 ATOM 2917 C CB . GLU A 1 388 ? -43.733 -9.750 26.397 1.00 60.02 ? 389 GLU A CB 1 ATOM 2918 C CG . GLU A 1 388 ? -45.057 -10.365 25.934 1.00 69.05 ? 389 GLU A CG 1 ATOM 2919 C CD . GLU A 1 388 ? -44.933 -11.837 25.541 1.00 82.52 ? 389 GLU A CD 1 ATOM 2920 O OE1 . GLU A 1 388 ? -43.861 -12.436 25.786 1.00 85.87 ? 389 GLU A OE1 1 ATOM 2921 O OE2 . GLU A 1 388 ? -45.905 -12.401 24.984 1.00 83.90 ? 389 GLU A OE2 1 ATOM 2922 N N . ASP A 1 389 ? -41.970 -8.121 28.924 1.00 54.33 ? 390 ASP A N 1 ATOM 2923 C CA . ASP A 1 389 ? -40.653 -7.568 29.228 1.00 58.63 ? 390 ASP A CA 1 ATOM 2924 C C . ASP A 1 389 ? -39.889 -8.513 30.159 1.00 70.16 ? 390 ASP A C 1 ATOM 2925 O O . ASP A 1 389 ? -40.288 -8.718 31.316 1.00 65.32 ? 390 ASP A O 1 ATOM 2926 C CB . ASP A 1 389 ? -40.787 -6.165 29.849 1.00 61.12 ? 390 ASP A CB 1 ATOM 2927 C CG . ASP A 1 389 ? -39.446 -5.576 30.301 1.00 67.93 ? 390 ASP A CG 1 ATOM 2928 O OD1 . ASP A 1 389 ? -38.378 -6.100 29.912 1.00 73.96 ? 390 ASP A OD1 1 ATOM 2929 O OD2 . ASP A 1 389 ? -39.462 -4.566 31.038 1.00 68.80 ? 390 ASP A OD2 1 ATOM 2930 N N . PRO A 1 390 ? -38.786 -9.093 29.648 1.00 67.98 ? 391 PRO A N 1 ATOM 2931 C CA . PRO A 1 390 ? -37.966 -10.082 30.361 1.00 65.97 ? 391 PRO A CA 1 ATOM 2932 C C . PRO A 1 390 ? -37.474 -9.652 31.748 1.00 67.47 ? 391 PRO A C 1 ATOM 2933 O O . PRO A 1 390 ? -37.642 -10.433 32.680 1.00 70.99 ? 391 PRO A O 1 ATOM 2934 C CB . PRO A 1 390 ? -36.800 -10.309 29.395 1.00 75.72 ? 391 PRO A CB 1 ATOM 2935 C CG . PRO A 1 390 ? -37.435 -10.115 28.036 1.00 52.83 ? 391 PRO A CG 1 ATOM 2936 C CD . PRO A 1 390 ? -38.340 -8.930 28.251 1.00 56.13 ? 391 PRO A CD 1 ATOM 2937 N N . ALA A 1 391 ? -36.908 -8.454 31.888 1.00 70.28 ? 392 ALA A N 1 ATOM 2938 C CA . ALA A 1 391 ? -36.420 -7.987 33.187 1.00 64.85 ? 392 ALA A CA 1 ATOM 2939 C C . ALA A 1 391 ? -37.539 -7.940 34.207 1.00 67.23 ? 392 ALA A C 1 ATOM 2940 O O . ALA A 1 391 ? -37.356 -8.344 35.351 1.00 72.46 ? 392 ALA A O 1 ATOM 2941 C CB . ALA A 1 391 ? -35.759 -6.615 33.079 1.00 58.86 ? 392 ALA A CB 1 ATOM 2942 N N . ARG A 1 392 ? -38.695 -7.437 33.796 1.00 66.46 ? 393 ARG A N 1 ATOM 2943 C CA . ARG A 1 392 ? -39.830 -7.342 34.695 1.00 59.31 ? 393 ARG A CA 1 ATOM 2944 C C . ARG A 1 392 ? -40.374 -8.728 35.052 1.00 62.55 ? 393 ARG A C 1 ATOM 2945 O O . ARG A 1 392 ? -40.781 -8.953 36.189 1.00 65.37 ? 393 ARG A O 1 ATOM 2946 C CB . ARG A 1 392 ? -40.926 -6.451 34.108 1.00 57.86 ? 393 ARG A CB 1 ATOM 2947 C CG . ARG A 1 392 ? -40.573 -4.982 34.078 1.00 50.36 ? 393 ARG A CG 1 ATOM 2948 C CD . ARG A 1 392 ? -41.789 -4.144 33.712 1.00 68.30 ? 393 ARG A CD 1 ATOM 2949 N NE . ARG A 1 392 ? -41.445 -3.066 32.779 1.00 79.50 ? 393 ARG A NE 1 ATOM 2950 C CZ . ARG A 1 392 ? -41.744 -1.785 32.977 1.00 80.31 ? 393 ARG A CZ 1 ATOM 2951 N NH1 . ARG A 1 392 ? -42.402 -1.407 34.075 1.00 84.07 ? 393 ARG A NH1 1 ATOM 2952 N NH2 . ARG A 1 392 ? -41.381 -0.881 32.082 1.00 67.62 ? 393 ARG A NH2 1 ATOM 2953 N N . LEU A 1 393 ? -40.358 -9.656 34.098 1.00 55.02 ? 394 LEU A N 1 ATOM 2954 C CA . LEU A 1 393 ? -40.816 -11.023 34.361 1.00 63.12 ? 394 LEU A CA 1 ATOM 2955 C C . LEU A 1 393 ? -39.901 -11.759 35.346 1.00 64.38 ? 394 LEU A C 1 ATOM 2956 O O . LEU A 1 393 ? -40.330 -12.691 36.020 1.00 61.77 ? 394 LEU A O 1 ATOM 2957 C CB . LEU A 1 393 ? -40.920 -11.842 33.070 1.00 54.38 ? 394 LEU A CB 1 ATOM 2958 C CG . LEU A 1 393 ? -41.925 -11.423 31.998 1.00 59.26 ? 394 LEU A CG 1 ATOM 2959 C CD1 . LEU A 1 393 ? -41.552 -12.117 30.693 1.00 62.01 ? 394 LEU A CD1 1 ATOM 2960 C CD2 . LEU A 1 393 ? -43.349 -11.765 32.404 1.00 51.06 ? 394 LEU A CD2 1 ATOM 2961 N N . ARG A 1 394 ? -38.638 -11.349 35.392 1.00 59.96 ? 395 ARG A N 1 ATOM 2962 C CA . ARG A 1 394 ? -37.653 -11.914 36.298 1.00 56.01 ? 395 ARG A CA 1 ATOM 2963 C C . ARG A 1 394 ? -37.929 -11.400 37.727 1.00 63.31 ? 395 ARG A C 1 ATOM 2964 O O . ARG A 1 394 ? -38.068 -12.180 38.664 1.00 61.00 ? 395 ARG A O 1 ATOM 2965 C CB . ARG A 1 394 ? -36.256 -11.513 35.829 1.00 57.77 ? 395 ARG A CB 1 ATOM 2966 C CG . ARG A 1 394 ? -35.103 -12.213 36.526 1.00 61.58 ? 395 ARG A CG 1 ATOM 2967 C CD . ARG A 1 394 ? -33.798 -11.511 36.184 1.00 55.80 ? 395 ARG A CD 1 ATOM 2968 N NE . ARG A 1 394 ? -33.952 -10.077 36.387 1.00 65.09 ? 395 ARG A NE 1 ATOM 2969 C CZ . ARG A 1 394 ? -33.205 -9.139 35.814 1.00 68.49 ? 395 ARG A CZ 1 ATOM 2970 N NH1 . ARG A 1 394 ? -32.220 -9.468 34.982 1.00 59.10 ? 395 ARG A NH1 1 ATOM 2971 N NH2 . ARG A 1 394 ? -33.452 -7.864 36.081 1.00 64.25 ? 395 ARG A NH2 1 ATOM 2972 N N . GLU A 1 395 ? -38.041 -10.085 37.879 1.00 60.09 ? 396 GLU A N 1 ATOM 2973 C CA . GLU A 1 395 ? -38.436 -9.487 39.144 1.00 56.79 ? 396 GLU A CA 1 ATOM 2974 C C . GLU A 1 395 ? -39.783 -9.984 39.667 1.00 57.40 ? 396 GLU A C 1 ATOM 2975 O O . GLU A 1 395 ? -40.021 -9.985 40.874 1.00 69.63 ? 396 GLU A O 1 ATOM 2976 C CB . GLU A 1 395 ? -38.495 -7.962 39.016 1.00 58.78 ? 396 GLU A CB 1 ATOM 2977 C CG . GLU A 1 395 ? -37.222 -7.247 39.373 1.00 55.12 ? 396 GLU A CG 1 ATOM 2978 C CD . GLU A 1 395 ? -36.107 -7.551 38.411 1.00 71.84 ? 396 GLU A CD 1 ATOM 2979 O OE1 . GLU A 1 395 ? -35.394 -8.557 38.634 1.00 70.77 ? 396 GLU A OE1 1 ATOM 2980 O OE2 . GLU A 1 395 ? -35.951 -6.784 37.428 1.00 75.80 ? 396 GLU A OE2 1 ATOM 2981 N N . ALA A 1 396 ? -40.677 -10.380 38.771 1.00 57.24 ? 397 ALA A N 1 ATOM 2982 C CA . ALA A 1 396 ? -42.025 -10.736 39.191 1.00 57.71 ? 397 ALA A CA 1 ATOM 2983 C C . ALA A 1 396 ? -42.053 -12.130 39.778 1.00 56.02 ? 397 ALA A C 1 ATOM 2984 O O . ALA A 1 396 ? -42.773 -12.374 40.729 1.00 56.01 ? 397 ALA A O 1 ATOM 2985 C CB . ALA A 1 396 ? -43.018 -10.616 38.038 1.00 44.41 ? 397 ALA A CB 1 ATOM 2986 N N . LEU A 1 397 ? -41.274 -13.042 39.203 1.00 54.59 ? 398 LEU A N 1 ATOM 2987 C CA . LEU A 1 397 ? -41.227 -14.407 39.694 1.00 52.77 ? 398 LEU A CA 1 ATOM 2988 C C . LEU A 1 397 ? -40.431 -14.437 41.006 1.00 54.69 ? 398 LEU A C 1 ATOM 2989 O O . LEU A 1 397 ? -40.694 -15.255 41.885 1.00 53.75 ? 398 LEU A O 1 ATOM 2990 C CB . LEU A 1 397 ? -40.606 -15.349 38.665 1.00 40.41 ? 398 LEU A CB 1 ATOM 2991 C CG . LEU A 1 397 ? -40.818 -16.810 39.057 1.00 50.14 ? 398 LEU A CG 1 ATOM 2992 C CD1 . LEU A 1 397 ? -42.287 -17.178 38.919 1.00 53.09 ? 398 LEU A CD1 1 ATOM 2993 C CD2 . LEU A 1 397 ? -39.934 -17.762 38.290 1.00 47.76 ? 398 LEU A CD2 1 ATOM 2994 N N . SER A 1 398 ? -39.462 -13.534 41.111 1.00 50.66 ? 399 SER A N 1 ATOM 2995 C CA . SER A 1 398 ? -38.730 -13.296 42.337 1.00 55.13 ? 399 SER A CA 1 ATOM 2996 C C . SER A 1 398 ? -39.725 -12.909 43.425 1.00 56.86 ? 399 SER A C 1 ATOM 2997 O O . SER A 1 398 ? -39.701 -13.471 44.513 1.00 52.33 ? 399 SER A O 1 ATOM 2998 C CB . SER A 1 398 ? -37.715 -12.177 42.126 1.00 57.09 ? 399 SER A CB 1 ATOM 2999 O OG . SER A 1 398 ? -36.879 -12.015 43.254 1.00 60.25 ? 399 SER A OG 1 ATOM 3000 N N . ASP A 1 399 ? -40.614 -11.968 43.112 1.00 54.42 ? 400 ASP A N 1 ATOM 3001 C CA . ASP A 1 399 ? -41.655 -11.549 44.050 1.00 55.72 ? 400 ASP A CA 1 ATOM 3002 C C . ASP A 1 399 ? -42.658 -12.659 44.393 1.00 60.15 ? 400 ASP A C 1 ATOM 3003 O O . ASP A 1 399 ? -43.064 -12.798 45.549 1.00 57.75 ? 400 ASP A O 1 ATOM 3004 C CB . ASP A 1 399 ? -42.423 -10.330 43.530 1.00 61.68 ? 400 ASP A CB 1 ATOM 3005 C CG . ASP A 1 399 ? -41.580 -9.071 43.497 1.00 70.74 ? 400 ASP A CG 1 ATOM 3006 O OD1 . ASP A 1 399 ? -40.531 -9.027 44.172 1.00 72.65 ? 400 ASP A OD1 1 ATOM 3007 O OD2 . ASP A 1 399 ? -41.986 -8.115 42.797 1.00 80.17 ? 400 ASP A OD2 1 ATOM 3008 N N . VAL A 1 400 ? -43.082 -13.428 43.395 1.00 56.71 ? 401 VAL A N 1 ATOM 3009 C CA . VAL A 1 400 ? -44.025 -14.510 43.646 1.00 56.85 ? 401 VAL A CA 1 ATOM 3010 C C . VAL A 1 400 ? -43.485 -15.445 44.738 1.00 56.77 ? 401 VAL A C 1 ATOM 3011 O O . VAL A 1 400 ? -44.188 -15.736 45.707 1.00 49.10 ? 401 VAL A O 1 ATOM 3012 C CB . VAL A 1 400 ? -44.326 -15.335 42.378 1.00 54.98 ? 401 VAL A CB 1 ATOM 3013 C CG1 . VAL A 1 400 ? -45.139 -16.577 42.729 1.00 52.60 ? 401 VAL A CG1 1 ATOM 3014 C CG2 . VAL A 1 400 ? -45.067 -14.500 41.360 1.00 62.28 ? 401 VAL A CG2 1 ATOM 3015 N N . VAL A 1 401 ? -42.242 -15.901 44.566 1.00 51.45 ? 402 VAL A N 1 ATOM 3016 C CA . VAL A 1 401 ? -41.629 -16.846 45.483 1.00 52.35 ? 402 VAL A CA 1 ATOM 3017 C C . VAL A 1 401 ? -41.373 -16.194 46.857 1.00 55.02 ? 402 VAL A C 1 ATOM 3018 O O . VAL A 1 401 ? -41.709 -16.767 47.883 1.00 51.16 ? 402 VAL A O 1 ATOM 3019 C CB . VAL A 1 401 ? -40.321 -17.431 44.912 1.00 56.24 ? 402 VAL A CB 1 ATOM 3020 C CG1 . VAL A 1 401 ? -39.477 -18.081 46.031 1.00 47.22 ? 402 VAL A CG1 1 ATOM 3021 C CG2 . VAL A 1 401 ? -40.628 -18.429 43.824 1.00 53.83 ? 402 VAL A CG2 1 ATOM 3022 N N . GLY A 1 402 ? -40.817 -14.983 46.848 1.00 55.35 ? 403 GLY A N 1 ATOM 3023 C CA . GLY A 1 402 ? -40.585 -14.200 48.047 1.00 49.89 ? 403 GLY A CA 1 ATOM 3024 C C . GLY A 1 402 ? -41.831 -13.825 48.826 1.00 51.83 ? 403 GLY A C 1 ATOM 3025 O O . GLY A 1 402 ? -41.822 -13.846 50.044 1.00 58.52 ? 403 GLY A O 1 ATOM 3026 N N . ASP A 1 403 ? -42.907 -13.470 48.139 1.00 55.48 ? 404 ASP A N 1 ATOM 3027 C CA . ASP A 1 403 ? -44.143 -13.096 48.817 1.00 52.95 ? 404 ASP A CA 1 ATOM 3028 C C . ASP A 1 403 ? -44.833 -14.304 49.446 1.00 53.75 ? 404 ASP A C 1 ATOM 3029 O O . ASP A 1 403 ? -45.286 -14.262 50.594 1.00 55.42 ? 404 ASP A O 1 ATOM 3030 C CB . ASP A 1 403 ? -45.119 -12.407 47.852 1.00 58.66 ? 404 ASP A CB 1 ATOM 3031 C CG . ASP A 1 403 ? -44.619 -11.051 47.360 1.00 65.35 ? 404 ASP A CG 1 ATOM 3032 O OD1 . ASP A 1 403 ? -43.604 -10.537 47.891 1.00 63.76 ? 404 ASP A OD1 1 ATOM 3033 O OD2 . ASP A 1 403 ? -45.258 -10.493 46.434 1.00 66.85 ? 404 ASP A OD2 1 ATOM 3034 N N . HIS A 1 404 ? -44.931 -15.378 48.678 1.00 55.60 ? 405 HIS A N 1 ATOM 3035 C CA . HIS A 1 404 ? -45.644 -16.572 49.119 1.00 52.46 ? 405 HIS A CA 1 ATOM 3036 C C . HIS A 1 404 ? -44.985 -17.142 50.373 1.00 51.37 ? 405 HIS A C 1 ATOM 3037 O O . HIS A 1 404 ? -45.654 -17.559 51.309 1.00 46.77 ? 405 HIS A O 1 ATOM 3038 C CB . HIS A 1 404 ? -45.619 -17.603 47.991 1.00 49.81 ? 405 HIS A CB 1 ATOM 3039 C CG . HIS A 1 404 ? -46.167 -18.945 48.362 1.00 46.13 ? 405 HIS A CG 1 ATOM 3040 N ND1 . HIS A 1 404 ? -47.410 -19.110 48.931 1.00 41.23 ? 405 HIS A ND1 1 ATOM 3041 C CD2 . HIS A 1 404 ? -45.652 -20.191 48.205 1.00 45.93 ? 405 HIS A CD2 1 ATOM 3042 C CE1 . HIS A 1 404 ? -47.629 -20.401 49.131 1.00 47.95 ? 405 HIS A CE1 1 ATOM 3043 N NE2 . HIS A 1 404 ? -46.579 -21.077 48.698 1.00 44.71 ? 405 HIS A NE2 1 ATOM 3044 N N . ASN A 1 405 ? -43.659 -17.148 50.369 1.00 52.99 ? 406 ASN A N 1 ATOM 3045 C CA . ASN A 1 405 ? -42.895 -17.882 51.347 1.00 46.43 ? 406 ASN A CA 1 ATOM 3046 C C . ASN A 1 405 ? -42.467 -17.059 52.554 1.00 53.81 ? 406 ASN A C 1 ATOM 3047 O O . ASN A 1 405 ? -42.287 -17.598 53.627 1.00 51.02 ? 406 ASN A O 1 ATOM 3048 C CB . ASN A 1 405 ? -41.674 -18.516 50.697 1.00 45.10 ? 406 ASN A CB 1 ATOM 3049 C CG . ASN A 1 405 ? -42.029 -19.721 49.844 1.00 55.91 ? 406 ASN A CG 1 ATOM 3050 O OD1 . ASN A 1 405 ? -42.535 -20.738 50.359 1.00 44.71 ? 406 ASN A OD1 1 ATOM 3051 N ND2 . ASN A 1 405 ? -41.759 -19.623 48.521 1.00 51.92 ? 406 ASN A ND2 1 ATOM 3052 N N . VAL A 1 406 ? -42.301 -15.758 52.374 1.00 54.12 ? 407 VAL A N 1 ATOM 3053 C CA . VAL A 1 406 ? -41.702 -14.936 53.410 1.00 47.53 ? 407 VAL A CA 1 ATOM 3054 C C . VAL A 1 406 ? -42.465 -13.655 53.737 1.00 54.62 ? 407 VAL A C 1 ATOM 3055 O O . VAL A 1 406 ? -42.907 -13.486 54.866 1.00 55.87 ? 407 VAL A O 1 ATOM 3056 C CB . VAL A 1 406 ? -40.243 -14.590 53.081 1.00 45.94 ? 407 VAL A CB 1 ATOM 3057 C CG1 . VAL A 1 406 ? -39.690 -13.663 54.129 1.00 51.82 ? 407 VAL A CG1 1 ATOM 3058 C CG2 . VAL A 1 406 ? -39.401 -15.865 52.973 1.00 43.46 ? 407 VAL A CG2 1 ATOM 3059 N N . VAL A 1 407 ? -42.620 -12.748 52.779 1.00 50.70 ? 408 VAL A N 1 ATOM 3060 C CA . VAL A 1 407 ? -43.159 -11.429 53.114 1.00 50.84 ? 408 VAL A CA 1 ATOM 3061 C C . VAL A 1 407 ? -44.595 -11.502 53.634 1.00 58.56 ? 408 VAL A C 1 ATOM 3062 O O . VAL A 1 407 ? -44.977 -10.805 54.570 1.00 62.04 ? 408 VAL A O 1 ATOM 3063 C CB . VAL A 1 407 ? -43.046 -10.439 51.931 1.00 54.92 ? 408 VAL A CB 1 ATOM 3064 C CG1 . VAL A 1 407 ? -43.684 -9.093 52.272 1.00 46.52 ? 408 VAL A CG1 1 ATOM 3065 C CG2 . VAL A 1 407 ? -41.587 -10.255 51.549 1.00 51.13 ? 408 VAL A CG2 1 ATOM 3066 N N . CYS A 1 408 ? -45.390 -12.379 53.052 1.00 57.50 ? 409 CYS A N 1 ATOM 3067 C CA . CYS A 1 408 ? -46.798 -12.431 53.418 1.00 55.97 ? 409 CYS A CA 1 ATOM 3068 C C . CYS A 1 408 ? -47.109 -13.265 54.685 1.00 58.59 ? 409 CYS A C 1 ATOM 3069 O O . CYS A 1 408 ? -47.996 -12.892 55.464 1.00 58.11 ? 409 CYS A O 1 ATOM 3070 C CB . CYS A 1 408 ? -47.664 -12.775 52.182 1.00 60.86 ? 409 CYS A CB 1 ATOM 3071 S SG . CYS A 1 408 ? -47.725 -11.362 50.941 1.00 59.56 ? 409 CYS A SG 1 ATOM 3072 N N . PRO A 1 409 ? -46.379 -14.376 54.911 1.00 46.72 ? 410 PRO A N 1 ATOM 3073 C CA . PRO A 1 409 ? -46.451 -14.976 56.252 1.00 55.61 ? 410 PRO A CA 1 ATOM 3074 C C . PRO A 1 409 ? -46.019 -14.019 57.382 1.00 51.25 ? 410 PRO A C 1 ATOM 3075 O O . PRO A 1 409 ? -46.753 -13.895 58.367 1.00 51.16 ? 410 PRO A O 1 ATOM 3076 C CB . PRO A 1 409 ? -45.492 -16.168 56.152 1.00 54.52 ? 410 PRO A CB 1 ATOM 3077 C CG . PRO A 1 409 ? -45.541 -16.549 54.676 1.00 48.99 ? 410 PRO A CG 1 ATOM 3078 C CD . PRO A 1 409 ? -45.637 -15.233 53.966 1.00 51.07 ? 410 PRO A CD 1 ATOM 3079 N N . VAL A 1 410 ? -44.865 -13.369 57.221 1.00 47.59 ? 411 VAL A N 1 ATOM 3080 C CA . VAL A 1 410 ? -44.343 -12.374 58.161 1.00 49.26 ? 411 VAL A CA 1 ATOM 3081 C C . VAL A 1 410 ? -45.311 -11.216 58.412 1.00 54.52 ? 411 VAL A C 1 ATOM 3082 O O . VAL A 1 410 ? -45.629 -10.916 59.568 1.00 57.83 ? 411 VAL A O 1 ATOM 3083 C CB . VAL A 1 410 ? -42.964 -11.818 57.712 1.00 45.23 ? 411 VAL A CB 1 ATOM 3084 C CG1 . VAL A 1 410 ? -42.582 -10.606 58.532 1.00 39.92 ? 411 VAL A CG1 1 ATOM 3085 C CG2 . VAL A 1 410 ? -41.880 -12.901 57.798 1.00 39.05 ? 411 VAL A CG2 1 ATOM 3086 N N . ALA A 1 411 ? -45.771 -10.573 57.341 1.00 50.35 ? 412 ALA A N 1 ATOM 3087 C CA . ALA A 1 411 ? -46.770 -9.503 57.443 1.00 53.76 ? 412 ALA A CA 1 ATOM 3088 C C . ALA A 1 411 ? -48.042 -9.914 58.199 1.00 54.54 ? 412 ALA A C 1 ATOM 3089 O O . ALA A 1 411 ? -48.622 -9.118 58.921 1.00 58.93 ? 412 ALA A O 1 ATOM 3090 C CB . ALA A 1 411 ? -47.146 -9.002 56.056 1.00 55.71 ? 412 ALA A CB 1 ATOM 3091 N N . GLN A 1 412 ? -48.502 -11.142 58.005 1.00 52.19 ? 413 GLN A N 1 ATOM 3092 C CA . GLN A 1 412 ? -49.739 -11.577 58.641 1.00 54.73 ? 413 GLN A CA 1 ATOM 3093 C C . GLN A 1 412 ? -49.500 -11.799 60.139 1.00 59.21 ? 413 GLN A C 1 ATOM 3094 O O . GLN A 1 412 ? -50.319 -11.405 60.984 1.00 57.23 ? 413 GLN A O 1 ATOM 3095 C CB . GLN A 1 412 ? -50.275 -12.847 57.977 1.00 57.56 ? 413 GLN A CB 1 ATOM 3096 C CG . GLN A 1 412 ? -51.622 -13.308 58.515 1.00 59.60 ? 413 GLN A CG 1 ATOM 3097 C CD . GLN A 1 412 ? -52.073 -14.627 57.907 1.00 69.99 ? 413 GLN A CD 1 ATOM 3098 O OE1 . GLN A 1 412 ? -51.287 -15.573 57.764 1.00 68.34 ? 413 GLN A OE1 1 ATOM 3099 N NE2 . GLN A 1 412 ? -53.346 -14.695 57.537 1.00 73.48 ? 413 GLN A NE2 1 ATOM 3100 N N . LEU A 1 413 ? -48.359 -12.415 60.453 1.00 58.71 ? 414 LEU A N 1 ATOM 3101 C CA . LEU A 1 413 ? -47.917 -12.604 61.831 1.00 53.46 ? 414 LEU A CA 1 ATOM 3102 C C . LEU A 1 413 ? -47.848 -11.271 62.583 1.00 59.34 ? 414 LEU A C 1 ATOM 3103 O O . LEU A 1 413 ? -48.425 -11.128 63.663 1.00 57.22 ? 414 LEU A O 1 ATOM 3104 C CB . LEU A 1 413 ? -46.552 -13.287 61.865 1.00 51.14 ? 414 LEU A CB 1 ATOM 3105 C CG . LEU A 1 413 ? -45.992 -13.492 63.284 1.00 59.10 ? 414 LEU A CG 1 ATOM 3106 C CD1 . LEU A 1 413 ? -46.794 -14.544 64.012 1.00 58.44 ? 414 LEU A CD1 1 ATOM 3107 C CD2 . LEU A 1 413 ? -44.518 -13.869 63.284 1.00 50.06 ? 414 LEU A CD2 1 ATOM 3108 N N . ALA A 1 414 ? -47.145 -10.300 61.999 1.00 58.71 ? 415 ALA A N 1 ATOM 3109 C CA . ALA A 1 414 ? -46.991 -8.968 62.587 1.00 56.96 ? 415 ALA A CA 1 ATOM 3110 C C . ALA A 1 414 ? -48.327 -8.271 62.862 1.00 60.57 ? 415 ALA A C 1 ATOM 3111 O O . ALA A 1 414 ? -48.466 -7.573 63.857 1.00 57.78 ? 415 ALA A O 1 ATOM 3112 C CB . ALA A 1 414 ? -46.120 -8.102 61.698 1.00 59.19 ? 415 ALA A CB 1 ATOM 3113 N N . GLY A 1 415 ? -49.308 -8.456 61.987 1.00 55.52 ? 416 GLY A N 1 ATOM 3114 C CA . GLY A 1 415 ? -50.611 -7.851 62.195 1.00 49.21 ? 416 GLY A CA 1 ATOM 3115 C C . GLY A 1 415 ? -51.440 -8.525 63.277 1.00 58.65 ? 416 GLY A C 1 ATOM 3116 O O . GLY A 1 415 ? -52.157 -7.870 64.045 1.00 60.26 ? 416 GLY A O 1 ATOM 3117 N N . ARG A 1 416 ? -51.364 -9.847 63.334 1.00 56.46 ? 417 ARG A N 1 ATOM 3118 C CA . ARG A 1 416 ? -52.087 -10.592 64.351 1.00 55.04 ? 417 ARG A CA 1 ATOM 3119 C C . ARG A 1 416 ? -51.502 -10.354 65.770 1.00 59.14 ? 417 ARG A C 1 ATOM 3120 O O . ARG A 1 416 ? -52.251 -10.187 66.731 1.00 60.37 ? 417 ARG A O 1 ATOM 3121 C CB . ARG A 1 416 ? -52.124 -12.078 63.987 1.00 61.85 ? 417 ARG A CB 1 ATOM 3122 C CG . ARG A 1 416 ? -53.244 -12.464 63.031 1.00 54.04 ? 417 ARG A CG 1 ATOM 3123 C CD . ARG A 1 416 ? -54.552 -11.911 63.540 1.00 56.56 ? 417 ARG A CD 1 ATOM 3124 N NE . ARG A 1 416 ? -55.719 -12.508 62.907 1.00 66.04 ? 417 ARG A NE 1 ATOM 3125 C CZ . ARG A 1 416 ? -56.693 -13.140 63.561 1.00 69.20 ? 417 ARG A CZ 1 ATOM 3126 N NH1 . ARG A 1 416 ? -56.645 -13.276 64.884 1.00 62.69 ? 417 ARG A NH1 1 ATOM 3127 N NH2 . ARG A 1 416 ? -57.728 -13.635 62.888 1.00 69.65 ? 417 ARG A NH2 1 ATOM 3128 N N . LEU A 1 417 ? -50.173 -10.308 65.883 1.00 54.46 ? 418 LEU A N 1 ATOM 3129 C CA . LEU A 1 417 ? -49.508 -9.989 67.145 1.00 56.00 ? 418 LEU A CA 1 ATOM 3130 C C . LEU A 1 417 ? -49.816 -8.576 67.621 1.00 62.63 ? 418 LEU A C 1 ATOM 3131 O O . LEU A 1 417 ? -50.154 -8.365 68.791 1.00 59.48 ? 418 LEU A O 1 ATOM 3132 C CB . LEU A 1 417 ? -47.988 -10.116 67.022 1.00 57.34 ? 418 LEU A CB 1 ATOM 3133 C CG . LEU A 1 417 ? -47.359 -11.471 66.712 1.00 59.91 ? 418 LEU A CG 1 ATOM 3134 C CD1 . LEU A 1 417 ? -45.850 -11.376 66.817 1.00 54.67 ? 418 LEU A CD1 1 ATOM 3135 C CD2 . LEU A 1 417 ? -47.909 -12.546 67.613 1.00 52.26 ? 418 LEU A CD2 1 ATOM 3136 N N . ALA A 1 418 ? -49.664 -7.604 66.722 1.00 58.20 ? 419 ALA A N 1 ATOM 3137 C CA . ALA A 1 418 ? -49.848 -6.204 67.085 1.00 52.50 ? 419 ALA A CA 1 ATOM 3138 C C . ALA A 1 418 ? -51.273 -5.926 67.551 1.00 58.27 ? 419 ALA A C 1 ATOM 3139 O O . ALA A 1 418 ? -51.495 -5.080 68.422 1.00 67.92 ? 419 ALA A O 1 ATOM 3140 C CB . ALA A 1 418 ? -49.473 -5.295 65.942 1.00 58.48 ? 419 ALA A CB 1 ATOM 3141 N N . ALA A 1 419 ? -52.227 -6.665 66.996 1.00 57.06 ? 420 ALA A N 1 ATOM 3142 C CA . ALA A 1 419 ? -53.641 -6.488 67.329 1.00 62.46 ? 420 ALA A CA 1 ATOM 3143 C C . ALA A 1 419 ? -54.046 -7.225 68.606 1.00 61.51 ? 420 ALA A C 1 ATOM 3144 O O . ALA A 1 419 ? -55.145 -7.035 69.133 1.00 54.60 ? 420 ALA A O 1 ATOM 3145 C CB . ALA A 1 419 ? -54.520 -6.950 66.159 1.00 55.26 ? 420 ALA A CB 1 ATOM 3146 N N . GLN A 1 420 ? -53.167 -8.087 69.094 1.00 61.82 ? 421 GLN A N 1 ATOM 3147 C CA . GLN A 1 420 ? -53.547 -8.973 70.181 1.00 63.06 ? 421 GLN A CA 1 ATOM 3148 C C . GLN A 1 420 ? -52.639 -8.827 71.404 1.00 65.44 ? 421 GLN A C 1 ATOM 3149 O O . GLN A 1 420 ? -52.519 -9.747 72.218 1.00 64.22 ? 421 GLN A O 1 ATOM 3150 C CB . GLN A 1 420 ? -53.634 -10.420 69.674 1.00 56.93 ? 421 GLN A CB 1 ATOM 3151 C CG . GLN A 1 420 ? -54.833 -10.624 68.773 1.00 62.94 ? 421 GLN A CG 1 ATOM 3152 C CD . GLN A 1 420 ? -54.729 -11.829 67.863 1.00 64.88 ? 421 GLN A CD 1 ATOM 3153 O OE1 . GLN A 1 420 ? -55.322 -11.847 66.785 1.00 66.62 ? 421 GLN A OE1 1 ATOM 3154 N NE2 . GLN A 1 420 ? -53.985 -12.842 68.289 1.00 59.63 ? 421 GLN A NE2 1 ATOM 3155 N N . GLY A 1 421 ? -52.007 -7.659 71.526 1.00 64.92 ? 422 GLY A N 1 ATOM 3156 C CA . GLY A 1 421 ? -51.221 -7.346 72.705 1.00 68.33 ? 422 GLY A CA 1 ATOM 3157 C C . GLY A 1 421 ? -49.798 -6.897 72.457 1.00 61.08 ? 422 GLY A C 1 ATOM 3158 O O . GLY A 1 421 ? -49.363 -5.875 72.969 1.00 75.54 ? 422 GLY A O 1 ATOM 3159 N N . ALA A 1 422 ? -49.067 -7.669 71.674 1.00 65.37 ? 423 ALA A N 1 ATOM 3160 C CA . ALA A 1 422 ? -47.663 -7.396 71.423 1.00 62.76 ? 423 ALA A CA 1 ATOM 3161 C C . ALA A 1 422 ? -47.408 -5.989 70.915 1.00 63.79 ? 423 ALA A C 1 ATOM 3162 O O . ALA A 1 422 ? -48.275 -5.334 70.336 1.00 64.28 ? 423 ALA A O 1 ATOM 3163 C CB . ALA A 1 422 ? -47.083 -8.415 70.448 1.00 60.12 ? 423 ALA A CB 1 ATOM 3164 N N . ARG A 1 423 ? -46.191 -5.545 71.167 1.00 57.74 ? 424 ARG A N 1 ATOM 3165 C CA . ARG A 1 423 ? -45.685 -4.299 70.672 1.00 56.41 ? 424 ARG A CA 1 ATOM 3166 C C . ARG A 1 423 ? -44.728 -4.730 69.576 1.00 63.30 ? 424 ARG A C 1 ATOM 3167 O O . ARG A 1 423 ? -43.756 -5.446 69.854 1.00 57.06 ? 424 ARG A O 1 ATOM 3168 C CB . ARG A 1 423 ? -44.933 -3.600 71.800 1.00 57.48 ? 424 ARG A CB 1 ATOM 3169 C CG . ARG A 1 423 ? -44.117 -2.408 71.385 1.00 68.12 ? 424 ARG A CG 1 ATOM 3170 C CD . ARG A 1 423 ? -44.999 -1.375 70.750 1.00 73.96 ? 424 ARG A CD 1 ATOM 3171 N NE . ARG A 1 423 ? -44.429 -0.035 70.845 1.00 87.41 ? 424 ARG A NE 1 ATOM 3172 C CZ . ARG A 1 423 ? -44.784 0.862 71.760 1.00 87.62 ? 424 ARG A CZ 1 ATOM 3173 N NH1 . ARG A 1 423 ? -45.704 0.555 72.667 1.00 86.50 ? 424 ARG A NH1 1 ATOM 3174 N NH2 . ARG A 1 423 ? -44.223 2.065 71.762 1.00 90.67 ? 424 ARG A NH2 1 ATOM 3175 N N . VAL A 1 424 ? -45.010 -4.324 68.336 1.00 55.61 ? 425 VAL A N 1 ATOM 3176 C CA . VAL A 1 424 ? -44.251 -4.803 67.175 1.00 54.41 ? 425 VAL A CA 1 ATOM 3177 C C . VAL A 1 424 ? -43.519 -3.681 66.428 1.00 58.18 ? 425 VAL A C 1 ATOM 3178 O O . VAL A 1 424 ? -44.054 -2.589 66.241 1.00 56.82 ? 425 VAL A O 1 ATOM 3179 C CB . VAL A 1 424 ? -45.172 -5.559 66.192 1.00 54.32 ? 425 VAL A CB 1 ATOM 3180 C CG1 . VAL A 1 424 ? -44.378 -6.136 65.052 1.00 55.75 ? 425 VAL A CG1 1 ATOM 3181 C CG2 . VAL A 1 424 ? -45.940 -6.652 66.920 1.00 52.79 ? 425 VAL A CG2 1 ATOM 3182 N N . TYR A 1 425 ? -42.276 -3.949 66.045 1.00 54.37 ? 426 TYR A N 1 ATOM 3183 C CA . TYR A 1 425 ? -41.514 -3.059 65.180 1.00 55.19 ? 426 TYR A CA 1 ATOM 3184 C C . TYR A 1 425 ? -41.118 -3.854 63.934 1.00 58.81 ? 426 TYR A C 1 ATOM 3185 O O . TYR A 1 425 ? -40.742 -5.022 64.046 1.00 54.97 ? 426 TYR A O 1 ATOM 3186 C CB . TYR A 1 425 ? -40.268 -2.530 65.899 1.00 59.34 ? 426 TYR A CB 1 ATOM 3187 C CG . TYR A 1 425 ? -40.578 -1.623 67.062 1.00 55.11 ? 426 TYR A CG 1 ATOM 3188 C CD1 . TYR A 1 425 ? -40.763 -0.257 66.872 1.00 56.02 ? 426 TYR A CD1 1 ATOM 3189 C CD2 . TYR A 1 425 ? -40.701 -2.130 68.356 1.00 55.58 ? 426 TYR A CD2 1 ATOM 3190 C CE1 . TYR A 1 425 ? -41.067 0.587 67.943 1.00 60.77 ? 426 TYR A CE1 1 ATOM 3191 C CE2 . TYR A 1 425 ? -41.009 -1.294 69.435 1.00 57.43 ? 426 TYR A CE2 1 ATOM 3192 C CZ . TYR A 1 425 ? -41.187 0.062 69.223 1.00 62.36 ? 426 TYR A CZ 1 ATOM 3193 O OH . TYR A 1 425 ? -41.485 0.895 70.282 1.00 66.94 ? 426 TYR A OH 1 ATOM 3194 N N . ALA A 1 426 ? -41.226 -3.237 62.753 1.00 58.59 ? 427 ALA A N 1 ATOM 3195 C CA . ALA A 1 426 ? -40.983 -3.941 61.486 1.00 50.26 ? 427 ALA A CA 1 ATOM 3196 C C . ALA A 1 426 ? -40.017 -3.202 60.566 1.00 53.26 ? 427 ALA A C 1 ATOM 3197 O O . ALA A 1 426 ? -40.035 -1.979 60.494 1.00 60.23 ? 427 ALA A O 1 ATOM 3198 C CB . ALA A 1 426 ? -42.289 -4.200 60.773 1.00 56.65 ? 427 ALA A CB 1 ATOM 3199 N N . TYR A 1 427 ? -39.174 -3.941 59.856 1.00 52.41 ? 428 TYR A N 1 ATOM 3200 C CA . TYR A 1 427 ? -38.247 -3.327 58.902 1.00 53.67 ? 428 TYR A CA 1 ATOM 3201 C C . TYR A 1 427 ? -38.241 -4.010 57.525 1.00 56.91 ? 428 TYR A C 1 ATOM 3202 O O . TYR A 1 427 ? -38.670 -5.156 57.384 1.00 53.85 ? 428 TYR A O 1 ATOM 3203 C CB . TYR A 1 427 ? -36.827 -3.350 59.463 1.00 52.81 ? 428 TYR A CB 1 ATOM 3204 C CG . TYR A 1 427 ? -36.267 -4.746 59.596 1.00 55.60 ? 428 TYR A CG 1 ATOM 3205 C CD1 . TYR A 1 427 ? -35.608 -5.357 58.531 1.00 55.25 ? 428 TYR A CD1 1 ATOM 3206 C CD2 . TYR A 1 427 ? -36.404 -5.462 60.786 1.00 58.01 ? 428 TYR A CD2 1 ATOM 3207 C CE1 . TYR A 1 427 ? -35.103 -6.648 58.638 1.00 57.66 ? 428 TYR A CE1 1 ATOM 3208 C CE2 . TYR A 1 427 ? -35.892 -6.750 60.912 1.00 59.15 ? 428 TYR A CE2 1 ATOM 3209 C CZ . TYR A 1 427 ? -35.240 -7.335 59.831 1.00 60.89 ? 428 TYR A CZ 1 ATOM 3210 O OH . TYR A 1 427 ? -34.734 -8.609 59.936 1.00 62.49 ? 428 TYR A OH 1 ATOM 3211 N N . VAL A 1 428 ? -37.740 -3.296 56.517 1.00 59.15 ? 429 VAL A N 1 ATOM 3212 C CA . VAL A 1 428 ? -37.301 -3.913 55.266 1.00 52.26 ? 429 VAL A CA 1 ATOM 3213 C C . VAL A 1 428 ? -35.847 -3.519 55.085 1.00 54.00 ? 429 VAL A C 1 ATOM 3214 O O . VAL A 1 428 ? -35.496 -2.356 55.224 1.00 60.94 ? 429 VAL A O 1 ATOM 3215 C CB . VAL A 1 428 ? -38.153 -3.472 54.028 1.00 60.33 ? 429 VAL A CB 1 ATOM 3216 C CG1 . VAL A 1 428 ? -37.541 -3.982 52.716 1.00 49.48 ? 429 VAL A CG1 1 ATOM 3217 C CG2 . VAL A 1 428 ? -39.571 -3.990 54.152 1.00 57.73 ? 429 VAL A CG2 1 ATOM 3218 N N . PHE A 1 429 ? -35.000 -4.498 54.808 1.00 56.92 ? 430 PHE A N 1 ATOM 3219 C CA . PHE A 1 429 ? -33.570 -4.270 54.684 1.00 56.20 ? 430 PHE A CA 1 ATOM 3220 C C . PHE A 1 429 ? -33.208 -4.091 53.204 1.00 64.23 ? 430 PHE A C 1 ATOM 3221 O O . PHE A 1 429 ? -33.236 -5.048 52.431 1.00 58.53 ? 430 PHE A O 1 ATOM 3222 C CB . PHE A 1 429 ? -32.821 -5.453 55.289 1.00 53.71 ? 430 PHE A CB 1 ATOM 3223 C CG . PHE A 1 429 ? -31.331 -5.322 55.239 1.00 61.61 ? 430 PHE A CG 1 ATOM 3224 C CD1 . PHE A 1 429 ? -30.646 -4.680 56.258 1.00 59.31 ? 430 PHE A CD1 1 ATOM 3225 C CD2 . PHE A 1 429 ? -30.607 -5.862 54.184 1.00 60.49 ? 430 PHE A CD2 1 ATOM 3226 C CE1 . PHE A 1 429 ? -29.268 -4.562 56.220 1.00 61.28 ? 430 PHE A CE1 1 ATOM 3227 C CE2 . PHE A 1 429 ? -29.219 -5.747 54.136 1.00 61.12 ? 430 PHE A CE2 1 ATOM 3228 C CZ . PHE A 1 429 ? -28.553 -5.094 55.152 1.00 65.97 ? 430 PHE A CZ 1 ATOM 3229 N N . GLU A 1 430 ? -32.856 -2.864 52.822 1.00 70.87 ? 431 GLU A N 1 ATOM 3230 C CA . GLU A 1 430 ? -32.687 -2.500 51.410 1.00 65.94 ? 431 GLU A CA 1 ATOM 3231 C C . GLU A 1 430 ? -31.270 -2.193 50.964 1.00 66.20 ? 431 GLU A C 1 ATOM 3232 O O . GLU A 1 430 ? -31.094 -1.535 49.954 1.00 67.74 ? 431 GLU A O 1 ATOM 3233 C CB . GLU A 1 430 ? -33.527 -1.274 51.074 1.00 63.16 ? 431 GLU A CB 1 ATOM 3234 C CG . GLU A 1 430 ? -34.996 -1.446 51.341 1.00 72.53 ? 431 GLU A CG 1 ATOM 3235 C CD . GLU A 1 430 ? -35.785 -0.212 50.976 1.00 86.15 ? 431 GLU A CD 1 ATOM 3236 O OE1 . GLU A 1 430 ? -35.155 0.841 50.711 1.00 85.11 ? 431 GLU A OE1 1 ATOM 3237 O OE2 . GLU A 1 430 ? -37.034 -0.300 50.954 1.00 93.58 ? 431 GLU A OE2 1 ATOM 3238 N N . HIS A 1 431 ? -30.262 -2.647 51.695 1.00 67.92 ? 432 HIS A N 1 ATOM 3239 C CA . HIS A 1 431 ? -28.897 -2.382 51.265 1.00 64.65 ? 432 HIS A CA 1 ATOM 3240 C C . HIS A 1 431 ? -28.194 -3.620 50.723 1.00 72.05 ? 432 HIS A C 1 ATOM 3241 O O . HIS A 1 431 ? -28.070 -4.633 51.419 1.00 72.43 ? 432 HIS A O 1 ATOM 3242 C CB . HIS A 1 431 ? -28.054 -1.758 52.376 1.00 67.55 ? 432 HIS A CB 1 ATOM 3243 C CG . HIS A 1 431 ? -26.635 -1.522 51.970 1.00 72.85 ? 432 HIS A CG 1 ATOM 3244 N ND1 . HIS A 1 431 ? -26.233 -0.388 51.295 1.00 76.19 ? 432 HIS A ND1 1 ATOM 3245 C CD2 . HIS A 1 431 ? -25.531 -2.298 52.093 1.00 73.16 ? 432 HIS A CD2 1 ATOM 3246 C CE1 . HIS A 1 431 ? -24.939 -0.467 51.042 1.00 76.74 ? 432 HIS A CE1 1 ATOM 3247 N NE2 . HIS A 1 431 ? -24.489 -1.617 51.513 1.00 74.72 ? 432 HIS A NE2 1 ATOM 3248 N N . ARG A 1 432 ? -27.717 -3.518 49.482 1.00 67.83 ? 433 ARG A N 1 ATOM 3249 C CA . ARG A 1 432 ? -26.945 -4.583 48.856 1.00 65.25 ? 433 ARG A CA 1 ATOM 3250 C C . ARG A 1 432 ? -25.476 -4.464 49.257 1.00 67.24 ? 433 ARG A C 1 ATOM 3251 O O . ARG A 1 432 ? -24.842 -3.452 48.993 1.00 71.55 ? 433 ARG A O 1 ATOM 3252 C CB . ARG A 1 432 ? -27.094 -4.505 47.336 1.00 70.19 ? 433 ARG A CB 1 ATOM 3253 C CG . ARG A 1 432 ? -26.540 -5.696 46.578 1.00 64.17 ? 433 ARG A CG 1 ATOM 3254 C CD . ARG A 1 432 ? -26.815 -5.583 45.071 1.00 65.52 ? 433 ARG A CD 1 ATOM 3255 N NE . ARG A 1 432 ? -26.547 -6.854 44.403 1.00 66.58 ? 433 ARG A NE 1 ATOM 3256 C CZ . ARG A 1 432 ? -25.334 -7.258 44.052 1.00 62.54 ? 433 ARG A CZ 1 ATOM 3257 N NH1 . ARG A 1 432 ? -24.289 -6.482 44.299 1.00 73.22 ? 433 ARG A NH1 1 ATOM 3258 N NH2 . ARG A 1 432 ? -25.161 -8.434 43.475 1.00 60.78 ? 433 ARG A NH2 1 ATOM 3259 N N . ALA A 1 433 ? -24.940 -5.488 49.911 1.00 70.75 ? 434 ALA A N 1 ATOM 3260 C CA . ALA A 1 433 ? -23.554 -5.445 50.370 1.00 72.19 ? 434 ALA A CA 1 ATOM 3261 C C . ALA A 1 433 ? -22.590 -5.295 49.197 1.00 73.30 ? 434 ALA A C 1 ATOM 3262 O O . ALA A 1 433 ? -22.718 -5.997 48.196 1.00 67.54 ? 434 ALA A O 1 ATOM 3263 C CB . ALA A 1 433 ? -23.220 -6.688 51.167 1.00 68.16 ? 434 ALA A CB 1 ATOM 3264 N N . SER A 1 434 ? -21.622 -4.387 49.336 1.00 77.79 ? 435 SER A N 1 ATOM 3265 C CA . SER A 1 434 ? -20.641 -4.107 48.283 1.00 65.30 ? 435 SER A CA 1 ATOM 3266 C C . SER A 1 434 ? -19.772 -5.318 47.949 1.00 64.46 ? 435 SER A C 1 ATOM 3267 O O . SER A 1 434 ? -19.195 -5.389 46.868 1.00 67.20 ? 435 SER A O 1 ATOM 3268 C CB . SER A 1 434 ? -19.754 -2.912 48.661 1.00 64.47 ? 435 SER A CB 1 ATOM 3269 O OG . SER A 1 434 ? -18.830 -3.242 49.685 1.00 69.56 ? 435 SER A OG 1 ATOM 3270 N N . THR A 1 435 ? -19.694 -6.269 48.875 1.00 65.32 ? 436 THR A N 1 ATOM 3271 C CA . THR A 1 435 ? -18.847 -7.455 48.725 1.00 61.73 ? 436 THR A CA 1 ATOM 3272 C C . THR A 1 435 ? -19.626 -8.648 48.158 1.00 60.97 ? 436 THR A C 1 ATOM 3273 O O . THR A 1 435 ? -19.073 -9.732 47.977 1.00 55.87 ? 436 THR A O 1 ATOM 3274 C CB . THR A 1 435 ? -18.253 -7.874 50.092 1.00 70.25 ? 436 THR A CB 1 ATOM 3275 O OG1 . THR A 1 435 ? -19.316 -8.189 51.011 1.00 68.19 ? 436 THR A OG1 1 ATOM 3276 C CG2 . THR A 1 435 ? -17.407 -6.754 50.682 1.00 69.60 ? 436 THR A CG2 1 ATOM 3277 N N . LEU A 1 436 ? -20.911 -8.435 47.886 1.00 61.97 ? 437 LEU A N 1 ATOM 3278 C CA . LEU A 1 436 ? -21.831 -9.508 47.509 1.00 64.08 ? 437 LEU A CA 1 ATOM 3279 C C . LEU A 1 436 ? -21.355 -10.271 46.276 1.00 62.09 ? 437 LEU A C 1 ATOM 3280 O O . LEU A 1 436 ? -20.996 -9.668 45.273 1.00 68.03 ? 437 LEU A O 1 ATOM 3281 C CB . LEU A 1 436 ? -23.238 -8.931 47.287 1.00 69.24 ? 437 LEU A CB 1 ATOM 3282 C CG . LEU A 1 436 ? -24.467 -9.848 47.301 1.00 66.63 ? 437 LEU A CG 1 ATOM 3283 C CD1 . LEU A 1 436 ? -24.331 -10.930 48.332 1.00 63.72 ? 437 LEU A CD1 1 ATOM 3284 C CD2 . LEU A 1 436 ? -25.702 -9.025 47.588 1.00 69.85 ? 437 LEU A CD2 1 ATOM 3285 N N . SER A 1 437 ? -21.358 -11.597 46.365 1.00 62.01 ? 438 SER A N 1 ATOM 3286 C CA . SER A 1 437 ? -20.846 -12.451 45.302 1.00 57.37 ? 438 SER A CA 1 ATOM 3287 C C . SER A 1 437 ? -21.932 -12.966 44.340 1.00 67.39 ? 438 SER A C 1 ATOM 3288 O O . SER A 1 437 ? -21.617 -13.557 43.306 1.00 65.59 ? 438 SER A O 1 ATOM 3289 C CB . SER A 1 437 ? -20.082 -13.632 45.893 1.00 59.11 ? 438 SER A CB 1 ATOM 3290 O OG . SER A 1 437 ? -20.975 -14.552 46.495 1.00 70.35 ? 438 SER A OG 1 ATOM 3291 N N . TRP A 1 438 ? -23.200 -12.756 44.687 1.00 65.00 ? 439 TRP A N 1 ATOM 3292 C CA . TRP A 1 438 ? -24.300 -13.105 43.797 1.00 61.19 ? 439 TRP A CA 1 ATOM 3293 C C . TRP A 1 438 ? -24.491 -11.962 42.817 1.00 61.59 ? 439 TRP A C 1 ATOM 3294 O O . TRP A 1 438 ? -24.213 -10.811 43.152 1.00 63.00 ? 439 TRP A O 1 ATOM 3295 C CB . TRP A 1 438 ? -25.606 -13.342 44.568 1.00 64.58 ? 439 TRP A CB 1 ATOM 3296 C CG . TRP A 1 438 ? -25.590 -14.514 45.509 1.00 64.70 ? 439 TRP A CG 1 ATOM 3297 C CD1 . TRP A 1 438 ? -25.300 -14.484 46.847 1.00 59.35 ? 439 TRP A CD1 1 ATOM 3298 C CD2 . TRP A 1 438 ? -25.884 -15.886 45.193 1.00 63.29 ? 439 TRP A CD2 1 ATOM 3299 N NE1 . TRP A 1 438 ? -25.385 -15.750 47.378 1.00 61.57 ? 439 TRP A NE1 1 ATOM 3300 C CE2 . TRP A 1 438 ? -25.746 -16.630 46.392 1.00 67.70 ? 439 TRP A CE2 1 ATOM 3301 C CE3 . TRP A 1 438 ? -26.250 -16.557 44.022 1.00 62.16 ? 439 TRP A CE3 1 ATOM 3302 C CZ2 . TRP A 1 438 ? -25.963 -18.013 46.450 1.00 60.59 ? 439 TRP A CZ2 1 ATOM 3303 C CZ3 . TRP A 1 438 ? -26.460 -17.932 44.078 1.00 64.43 ? 439 TRP A CZ3 1 ATOM 3304 C CH2 . TRP A 1 438 ? -26.319 -18.642 45.289 1.00 70.85 ? 439 TRP A CH2 1 ATOM 3305 N N . PRO A 1 439 ? -24.970 -12.274 41.602 1.00 61.60 ? 440 PRO A N 1 ATOM 3306 C CA . PRO A 1 439 ? -25.161 -11.263 40.552 1.00 59.82 ? 440 PRO A CA 1 ATOM 3307 C C . PRO A 1 439 ? -26.148 -10.173 40.939 1.00 61.40 ? 440 PRO A C 1 ATOM 3308 O O . PRO A 1 439 ? -26.858 -10.292 41.939 1.00 70.94 ? 440 PRO A O 1 ATOM 3309 C CB . PRO A 1 439 ? -25.706 -12.071 39.371 1.00 55.41 ? 440 PRO A CB 1 ATOM 3310 C CG . PRO A 1 439 ? -26.211 -13.341 39.958 1.00 66.31 ? 440 PRO A CG 1 ATOM 3311 C CD . PRO A 1 439 ? -25.326 -13.624 41.138 1.00 60.78 ? 440 PRO A CD 1 ATOM 3312 N N . LEU A 1 440 ? -26.193 -9.121 40.133 1.00 64.36 ? 441 LEU A N 1 ATOM 3313 C CA . LEU A 1 440 ? -26.968 -7.929 40.449 1.00 58.30 ? 441 LEU A CA 1 ATOM 3314 C C . LEU A 1 440 ? -28.486 -8.082 40.268 1.00 61.51 ? 441 LEU A C 1 ATOM 3315 O O . LEU A 1 440 ? -29.268 -7.354 40.891 1.00 67.83 ? 441 LEU A O 1 ATOM 3316 C CB . LEU A 1 440 ? -26.454 -6.748 39.620 1.00 66.59 ? 441 LEU A CB 1 ATOM 3317 C CG . LEU A 1 440 ? -27.123 -5.414 39.950 1.00 74.59 ? 441 LEU A CG 1 ATOM 3318 C CD1 . LEU A 1 440 ? -26.791 -4.977 41.385 1.00 65.58 ? 441 LEU A CD1 1 ATOM 3319 C CD2 . LEU A 1 440 ? -26.796 -4.338 38.928 1.00 55.78 ? 441 LEU A CD2 1 ATOM 3320 N N . TRP A 1 441 ? -28.920 -9.018 39.430 1.00 62.23 ? 442 TRP A N 1 ATOM 3321 C CA . TRP A 1 441 ? -30.359 -9.174 39.216 1.00 65.90 ? 442 TRP A CA 1 ATOM 3322 C C . TRP A 1 441 ? -31.024 -9.723 40.470 1.00 64.48 ? 442 TRP A C 1 ATOM 3323 O O . TRP A 1 441 ? -32.218 -9.515 40.689 1.00 63.61 ? 442 TRP A O 1 ATOM 3324 C CB . TRP A 1 441 ? -30.686 -10.046 37.991 1.00 56.18 ? 442 TRP A CB 1 ATOM 3325 C CG . TRP A 1 441 ? -30.238 -11.472 38.082 1.00 53.97 ? 442 TRP A CG 1 ATOM 3326 C CD1 . TRP A 1 441 ? -29.077 -11.992 37.603 1.00 56.91 ? 442 TRP A CD1 1 ATOM 3327 C CD2 . TRP A 1 441 ? -30.953 -12.564 38.674 1.00 58.02 ? 442 TRP A CD2 1 ATOM 3328 N NE1 . TRP A 1 441 ? -29.014 -13.337 37.866 1.00 57.71 ? 442 TRP A NE1 1 ATOM 3329 C CE2 . TRP A 1 441 ? -30.151 -13.714 38.528 1.00 56.29 ? 442 TRP A CE2 1 ATOM 3330 C CE3 . TRP A 1 441 ? -32.183 -12.677 39.341 1.00 62.93 ? 442 TRP A CE3 1 ATOM 3331 C CZ2 . TRP A 1 441 ? -30.539 -14.969 39.014 1.00 55.29 ? 442 TRP A CZ2 1 ATOM 3332 C CZ3 . TRP A 1 441 ? -32.575 -13.928 39.818 1.00 56.52 ? 442 TRP A CZ3 1 ATOM 3333 C CH2 . TRP A 1 441 ? -31.752 -15.057 39.648 1.00 56.03 ? 442 TRP A CH2 1 ATOM 3334 N N . MET A 1 442 ? -30.236 -10.415 41.290 1.00 61.34 ? 443 MET A N 1 ATOM 3335 C CA . MET A 1 442 ? -30.720 -10.950 42.560 1.00 61.61 ? 443 MET A CA 1 ATOM 3336 C C . MET A 1 442 ? -30.965 -9.872 43.626 1.00 60.97 ? 443 MET A C 1 ATOM 3337 O O . MET A 1 442 ? -31.706 -10.099 44.578 1.00 61.62 ? 443 MET A O 1 ATOM 3338 C CB . MET A 1 442 ? -29.779 -12.032 43.081 1.00 55.73 ? 443 MET A CB 1 ATOM 3339 C CG . MET A 1 442 ? -29.852 -13.324 42.286 1.00 54.32 ? 443 MET A CG 1 ATOM 3340 S SD . MET A 1 442 ? -28.902 -14.612 43.103 1.00 63.13 ? 443 MET A SD 1 ATOM 3341 C CE . MET A 1 442 ? -29.307 -16.033 42.118 1.00 58.76 ? 443 MET A CE 1 ATOM 3342 N N . GLY A 1 443 ? -30.356 -8.700 43.458 1.00 63.38 ? 444 GLY A N 1 ATOM 3343 C CA . GLY A 1 443 ? -30.575 -7.581 44.365 1.00 56.98 ? 444 GLY A CA 1 ATOM 3344 C C . GLY A 1 443 ? -30.038 -7.822 45.768 1.00 62.89 ? 444 GLY A C 1 ATOM 3345 O O . GLY A 1 443 ? -28.866 -8.169 45.933 1.00 65.37 ? 444 GLY A O 1 ATOM 3346 N N . VAL A 1 444 ? -30.891 -7.620 46.775 1.00 60.68 ? 445 VAL A N 1 ATOM 3347 C CA . VAL A 1 444 ? -30.570 -7.941 48.171 1.00 57.11 ? 445 VAL A CA 1 ATOM 3348 C C . VAL A 1 444 ? -31.238 -9.259 48.536 1.00 55.16 ? 445 VAL A C 1 ATOM 3349 O O . VAL A 1 444 ? -32.429 -9.287 48.837 1.00 54.79 ? 445 VAL A O 1 ATOM 3350 C CB . VAL A 1 444 ? -31.129 -6.880 49.120 1.00 60.75 ? 445 VAL A CB 1 ATOM 3351 C CG1 . VAL A 1 444 ? -30.608 -7.115 50.530 1.00 58.80 ? 445 VAL A CG1 1 ATOM 3352 C CG2 . VAL A 1 444 ? -30.792 -5.471 48.626 1.00 60.36 ? 445 VAL A CG2 1 ATOM 3353 N N . PRO A 1 445 ? -30.496 -10.367 48.470 1.00 53.32 ? 446 PRO A N 1 ATOM 3354 C CA . PRO A 1 445 ? -31.220 -11.632 48.658 1.00 55.54 ? 446 PRO A CA 1 ATOM 3355 C C . PRO A 1 445 ? -31.353 -12.142 50.111 1.00 64.94 ? 446 PRO A C 1 ATOM 3356 O O . PRO A 1 445 ? -30.931 -11.509 51.086 1.00 62.58 ? 446 PRO A O 1 ATOM 3357 C CB . PRO A 1 445 ? -30.430 -12.628 47.802 1.00 54.36 ? 446 PRO A CB 1 ATOM 3358 C CG . PRO A 1 445 ? -29.056 -12.043 47.674 1.00 54.63 ? 446 PRO A CG 1 ATOM 3359 C CD . PRO A 1 445 ? -29.152 -10.553 47.895 1.00 57.61 ? 446 PRO A CD 1 ATOM 3360 N N . HIS A 1 446 ? -31.990 -13.303 50.215 1.00 62.28 ? 447 HIS A N 1 ATOM 3361 C CA . HIS A 1 446 ? -32.241 -13.990 51.463 1.00 54.54 ? 447 HIS A CA 1 ATOM 3362 C C . HIS A 1 446 ? -30.940 -14.199 52.221 1.00 63.48 ? 447 HIS A C 1 ATOM 3363 O O . HIS A 1 446 ? -30.006 -14.824 51.708 1.00 59.44 ? 447 HIS A O 1 ATOM 3364 C CB . HIS A 1 446 ? -32.873 -15.347 51.157 1.00 56.48 ? 447 HIS A CB 1 ATOM 3365 C CG . HIS A 1 446 ? -33.572 -15.981 52.323 1.00 64.56 ? 447 HIS A CG 1 ATOM 3366 N ND1 . HIS A 1 446 ? -34.705 -15.443 52.898 1.00 59.46 ? 447 HIS A ND1 1 ATOM 3367 C CD2 . HIS A 1 446 ? -33.316 -17.128 52.998 1.00 55.08 ? 447 HIS A CD2 1 ATOM 3368 C CE1 . HIS A 1 446 ? -35.114 -16.230 53.878 1.00 57.08 ? 447 HIS A CE1 1 ATOM 3369 N NE2 . HIS A 1 446 ? -34.289 -17.258 53.960 1.00 56.55 ? 447 HIS A NE2 1 ATOM 3370 N N . GLY A 1 447 ? -30.885 -13.654 53.436 1.00 58.00 ? 448 GLY A N 1 ATOM 3371 C CA . GLY A 1 447 ? -29.796 -13.906 54.361 1.00 56.76 ? 448 GLY A CA 1 ATOM 3372 C C . GLY A 1 447 ? -28.615 -12.962 54.301 1.00 62.94 ? 448 GLY A C 1 ATOM 3373 O O . GLY A 1 447 ? -27.562 -13.256 54.861 1.00 64.67 ? 448 GLY A O 1 ATOM 3374 N N . TYR A 1 448 ? -28.783 -11.825 53.631 1.00 67.96 ? 449 TYR A N 1 ATOM 3375 C CA . TYR A 1 448 ? -27.666 -10.901 53.408 1.00 67.52 ? 449 TYR A CA 1 ATOM 3376 C C . TYR A 1 448 ? -27.727 -9.647 54.267 1.00 66.10 ? 449 TYR A C 1 ATOM 3377 O O . TYR A 1 448 ? -26.915 -8.736 54.129 1.00 71.46 ? 449 TYR A O 1 ATOM 3378 C CB . TYR A 1 448 ? -27.441 -10.643 51.902 1.00 60.02 ? 449 TYR A CB 1 ATOM 3379 C CG . TYR A 1 448 ? -26.757 -11.857 51.357 1.00 60.83 ? 449 TYR A CG 1 ATOM 3380 C CD1 . TYR A 1 448 ? -25.385 -12.009 51.500 1.00 57.68 ? 449 TYR A CD1 1 ATOM 3381 C CD2 . TYR A 1 448 ? -27.487 -12.914 50.827 1.00 60.03 ? 449 TYR A CD2 1 ATOM 3382 C CE1 . TYR A 1 448 ? -24.749 -13.147 51.077 1.00 60.65 ? 449 TYR A CE1 1 ATOM 3383 C CE2 . TYR A 1 448 ? -26.854 -14.065 50.399 1.00 55.02 ? 449 TYR A CE2 1 ATOM 3384 C CZ . TYR A 1 448 ? -25.485 -14.174 50.532 1.00 57.21 ? 449 TYR A CZ 1 ATOM 3385 O OH . TYR A 1 448 ? -24.834 -15.311 50.128 1.00 58.42 ? 449 TYR A OH 1 ATOM 3386 N N . GLU A 1 449 ? -28.691 -9.636 55.178 1.00 63.87 ? 450 GLU A N 1 ATOM 3387 C CA . GLU A 1 449 ? -28.740 -8.635 56.229 1.00 65.13 ? 450 GLU A CA 1 ATOM 3388 C C . GLU A 1 449 ? -27.954 -9.132 57.449 1.00 60.88 ? 450 GLU A C 1 ATOM 3389 O O . GLU A 1 449 ? -27.487 -8.334 58.252 1.00 58.59 ? 450 GLU A O 1 ATOM 3390 C CB . GLU A 1 449 ? -30.199 -8.280 56.592 1.00 61.74 ? 450 GLU A CB 1 ATOM 3391 C CG . GLU A 1 449 ? -30.851 -9.096 57.724 1.00 61.79 ? 450 GLU A CG 1 ATOM 3392 C CD . GLU A 1 449 ? -31.324 -10.504 57.316 1.00 69.95 ? 450 GLU A CD 1 ATOM 3393 O OE1 . GLU A 1 449 ? -30.815 -11.066 56.318 1.00 67.41 ? 450 GLU A OE1 1 ATOM 3394 O OE2 . GLU A 1 449 ? -32.212 -11.056 58.012 1.00 70.34 ? 450 GLU A OE2 1 ATOM 3395 N N . ILE A 1 450 ? -27.786 -10.448 57.560 1.00 60.84 ? 451 ILE A N 1 ATOM 3396 C CA . ILE A 1 450 ? -27.180 -11.047 58.752 1.00 65.92 ? 451 ILE A CA 1 ATOM 3397 C C . ILE A 1 450 ? -25.784 -10.495 59.017 1.00 62.75 ? 451 ILE A C 1 ATOM 3398 O O . ILE A 1 450 ? -25.490 -10.063 60.124 1.00 61.92 ? 451 ILE A O 1 ATOM 3399 C CB . ILE A 1 450 ? -27.092 -12.592 58.661 1.00 62.54 ? 451 ILE A CB 1 ATOM 3400 C CG1 . ILE A 1 450 ? -28.481 -13.225 58.680 1.00 59.42 ? 451 ILE A CG1 1 ATOM 3401 C CG2 . ILE A 1 450 ? -26.267 -13.145 59.800 1.00 54.82 ? 451 ILE A CG2 1 ATOM 3402 C CD1 . ILE A 1 450 ? -28.452 -14.714 58.420 1.00 55.72 ? 451 ILE A CD1 1 ATOM 3403 N N . GLU A 1 451 ? -24.939 -10.488 57.989 1.00 63.11 ? 452 GLU A N 1 ATOM 3404 C CA . GLU A 1 451 ? -23.545 -10.084 58.148 1.00 59.55 ? 452 GLU A CA 1 ATOM 3405 C C . GLU A 1 451 ? -23.383 -8.668 58.693 1.00 64.52 ? 452 GLU A C 1 ATOM 3406 O O . GLU A 1 451 ? -22.346 -8.339 59.263 1.00 66.51 ? 452 GLU A O 1 ATOM 3407 C CB . GLU A 1 451 ? -22.783 -10.240 56.838 1.00 65.57 ? 452 GLU A CB 1 ATOM 3408 C CG . GLU A 1 451 ? -23.437 -9.553 55.649 1.00 69.87 ? 452 GLU A CG 1 ATOM 3409 C CD . GLU A 1 451 ? -22.801 -9.954 54.334 1.00 72.59 ? 452 GLU A CD 1 ATOM 3410 O OE1 . GLU A 1 451 ? -22.271 -9.066 53.639 1.00 84.61 ? 452 GLU A OE1 1 ATOM 3411 O OE2 . GLU A 1 451 ? -22.828 -11.156 53.993 1.00 76.54 ? 452 GLU A OE2 1 ATOM 3412 N N . PHE A 1 452 ? -24.413 -7.844 58.533 1.00 60.46 ? 453 PHE A N 1 ATOM 3413 C CA . PHE A 1 452 ? -24.401 -6.495 59.079 1.00 60.23 ? 453 PHE A CA 1 ATOM 3414 C C . PHE A 1 452 ? -24.904 -6.459 60.516 1.00 64.81 ? 453 PHE A C 1 ATOM 3415 O O . PHE A 1 452 ? -24.454 -5.643 61.309 1.00 66.31 ? 453 PHE A O 1 ATOM 3416 C CB . PHE A 1 452 ? -25.242 -5.557 58.223 1.00 58.87 ? 453 PHE A CB 1 ATOM 3417 C CG . PHE A 1 452 ? -24.641 -5.265 56.889 1.00 67.30 ? 453 PHE A CG 1 ATOM 3418 C CD1 . PHE A 1 452 ? -24.829 -6.137 55.820 1.00 70.73 ? 453 PHE A CD1 1 ATOM 3419 C CD2 . PHE A 1 452 ? -23.882 -4.122 56.694 1.00 66.62 ? 453 PHE A CD2 1 ATOM 3420 C CE1 . PHE A 1 452 ? -24.270 -5.875 54.579 1.00 68.33 ? 453 PHE A CE1 1 ATOM 3421 C CE2 . PHE A 1 452 ? -23.325 -3.848 55.449 1.00 71.22 ? 453 PHE A CE2 1 ATOM 3422 C CZ . PHE A 1 452 ? -23.517 -4.728 54.394 1.00 69.64 ? 453 PHE A CZ 1 ATOM 3423 N N . ILE A 1 453 ? -25.844 -7.337 60.846 1.00 63.24 ? 454 ILE A N 1 ATOM 3424 C CA . ILE A 1 453 ? -26.402 -7.380 62.187 1.00 56.53 ? 454 ILE A CA 1 ATOM 3425 C C . ILE A 1 453 ? -25.312 -7.820 63.174 1.00 65.93 ? 454 ILE A C 1 ATOM 3426 O O . ILE A 1 453 ? -25.277 -7.367 64.327 1.00 66.57 ? 454 ILE A O 1 ATOM 3427 C CB . ILE A 1 453 ? -27.619 -8.339 62.276 1.00 57.68 ? 454 ILE A CB 1 ATOM 3428 C CG1 . ILE A 1 453 ? -28.677 -8.012 61.223 1.00 63.42 ? 454 ILE A CG1 1 ATOM 3429 C CG2 . ILE A 1 453 ? -28.259 -8.273 63.651 1.00 70.15 ? 454 ILE A CG2 1 ATOM 3430 C CD1 . ILE A 1 453 ? -29.374 -6.695 61.421 1.00 61.73 ? 454 ILE A CD1 1 ATOM 3431 N N . PHE A 1 454 ? -24.423 -8.702 62.717 1.00 57.75 ? 455 PHE A N 1 ATOM 3432 C CA . PHE A 1 454 ? -23.295 -9.147 63.529 1.00 56.82 ? 455 PHE A CA 1 ATOM 3433 C C . PHE A 1 454 ? -22.055 -8.262 63.346 1.00 67.45 ? 455 PHE A C 1 ATOM 3434 O O . PHE A 1 454 ? -21.012 -8.536 63.940 1.00 70.24 ? 455 PHE A O 1 ATOM 3435 C CB . PHE A 1 454 ? -22.907 -10.580 63.180 1.00 59.80 ? 455 PHE A CB 1 ATOM 3436 C CG . PHE A 1 454 ? -23.830 -11.628 63.731 1.00 60.95 ? 455 PHE A CG 1 ATOM 3437 C CD1 . PHE A 1 454 ? -25.063 -11.864 63.149 1.00 59.83 ? 455 PHE A CD1 1 ATOM 3438 C CD2 . PHE A 1 454 ? -23.439 -12.417 64.800 1.00 58.78 ? 455 PHE A CD2 1 ATOM 3439 C CE1 . PHE A 1 454 ? -25.896 -12.849 63.634 1.00 59.05 ? 455 PHE A CE1 1 ATOM 3440 C CE2 . PHE A 1 454 ? -24.271 -13.401 65.298 1.00 61.76 ? 455 PHE A CE2 1 ATOM 3441 C CZ . PHE A 1 454 ? -25.501 -13.619 64.714 1.00 62.49 ? 455 PHE A CZ 1 ATOM 3442 N N . GLY A 1 455 ? -22.156 -7.233 62.501 1.00 63.28 ? 456 GLY A N 1 ATOM 3443 C CA . GLY A 1 455 ? -21.081 -6.271 62.329 1.00 57.04 ? 456 GLY A CA 1 ATOM 3444 C C . GLY A 1 455 ? -19.802 -6.836 61.737 1.00 64.82 ? 456 GLY A C 1 ATOM 3445 O O . GLY A 1 455 ? -18.710 -6.346 62.005 1.00 64.43 ? 456 GLY A O 1 ATOM 3446 N N . ILE A 1 456 ? -19.942 -7.867 60.912 1.00 70.07 ? 457 ILE A N 1 ATOM 3447 C CA . ILE A 1 456 ? -18.842 -8.377 60.092 1.00 62.51 ? 457 ILE A CA 1 ATOM 3448 C C . ILE A 1 456 ? -18.092 -7.304 59.252 1.00 65.23 ? 457 ILE A C 1 ATOM 3449 O O . ILE A 1 456 ? -16.915 -7.480 58.935 1.00 69.82 ? 457 ILE A O 1 ATOM 3450 C CB . ILE A 1 456 ? -19.338 -9.553 59.206 1.00 67.97 ? 457 ILE A CB 1 ATOM 3451 C CG1 . ILE A 1 456 ? -20.065 -10.589 60.067 1.00 61.20 ? 457 ILE A CG1 1 ATOM 3452 C CG2 . ILE A 1 456 ? -18.193 -10.214 58.437 1.00 61.97 ? 457 ILE A CG2 1 ATOM 3453 C CD1 . ILE A 1 456 ? -19.162 -11.286 61.071 1.00 60.68 ? 457 ILE A CD1 1 ATOM 3454 N N . PRO A 1 457 ? -18.753 -6.191 58.882 1.00 67.81 ? 458 PRO A N 1 ATOM 3455 C CA . PRO A 1 457 ? -17.931 -5.163 58.223 1.00 69.59 ? 458 PRO A CA 1 ATOM 3456 C C . PRO A 1 457 ? -16.818 -4.532 59.081 1.00 74.69 ? 458 PRO A C 1 ATOM 3457 O O . PRO A 1 457 ? -15.915 -3.907 58.521 1.00 79.55 ? 458 PRO A O 1 ATOM 3458 C CB . PRO A 1 457 ? -18.960 -4.096 57.847 1.00 71.24 ? 458 PRO A CB 1 ATOM 3459 C CG . PRO A 1 457 ? -20.195 -4.866 57.592 1.00 71.07 ? 458 PRO A CG 1 ATOM 3460 C CD . PRO A 1 457 ? -20.190 -5.965 58.629 1.00 67.19 ? 458 PRO A CD 1 ATOM 3461 N N . LEU A 1 458 ? -16.871 -4.679 60.402 1.00 71.79 ? 459 LEU A N 1 ATOM 3462 C CA . LEU A 1 458 ? -15.808 -4.140 61.250 1.00 74.68 ? 459 LEU A CA 1 ATOM 3463 C C . LEU A 1 458 ? -14.510 -4.944 61.151 1.00 77.11 ? 459 LEU A C 1 ATOM 3464 O O . LEU A 1 458 ? -13.461 -4.490 61.605 1.00 83.62 ? 459 LEU A O 1 ATOM 3465 C CB . LEU A 1 458 ? -16.258 -4.025 62.710 1.00 69.27 ? 459 LEU A CB 1 ATOM 3466 C CG . LEU A 1 458 ? -17.517 -3.181 62.919 1.00 68.75 ? 459 LEU A CG 1 ATOM 3467 C CD1 . LEU A 1 458 ? -17.794 -3.002 64.391 1.00 62.61 ? 459 LEU A CD1 1 ATOM 3468 C CD2 . LEU A 1 458 ? -17.404 -1.838 62.221 1.00 65.36 ? 459 LEU A CD2 1 ATOM 3469 N N . ASP A 1 459 ? -14.587 -6.132 60.557 1.00 70.11 ? 460 ASP A N 1 ATOM 3470 C CA . ASP A 1 459 ? -13.426 -7.003 60.424 1.00 76.14 ? 460 ASP A CA 1 ATOM 3471 C C . ASP A 1 459 ? -12.453 -6.429 59.388 1.00 89.14 ? 460 ASP A C 1 ATOM 3472 O O . ASP A 1 459 ? -12.827 -6.188 58.229 1.00 90.99 ? 460 ASP A O 1 ATOM 3473 C CB . ASP A 1 459 ? -13.866 -8.432 60.070 1.00 75.12 ? 460 ASP A CB 1 ATOM 3474 C CG . ASP A 1 459 ? -12.693 -9.416 59.942 1.00 85.30 ? 460 ASP A CG 1 ATOM 3475 O OD1 . ASP A 1 459 ? -11.536 -9.059 60.248 1.00 86.60 ? 460 ASP A OD1 1 ATOM 3476 O OD2 . ASP A 1 459 ? -12.940 -10.576 59.536 1.00 83.72 ? 460 ASP A OD2 1 ATOM 3477 N N . PRO A 1 460 ? -11.202 -6.186 59.820 1.00 93.49 ? 461 PRO A N 1 ATOM 3478 C CA . PRO A 1 460 ? -10.117 -5.646 58.992 1.00 84.94 ? 461 PRO A CA 1 ATOM 3479 C C . PRO A 1 460 ? -9.809 -6.499 57.767 1.00 87.12 ? 461 PRO A C 1 ATOM 3480 O O . PRO A 1 460 ? -9.615 -5.947 56.683 1.00 90.21 ? 461 PRO A O 1 ATOM 3481 C CB . PRO A 1 460 ? -8.916 -5.661 59.942 1.00 88.87 ? 461 PRO A CB 1 ATOM 3482 C CG . PRO A 1 460 ? -9.508 -5.564 61.300 1.00 91.08 ? 461 PRO A CG 1 ATOM 3483 C CD . PRO A 1 460 ? -10.799 -6.319 61.236 1.00 86.00 ? 461 PRO A CD 1 ATOM 3484 N N . SER A 1 461 ? -9.771 -7.818 57.932 1.00 84.98 ? 462 SER A N 1 ATOM 3485 C CA . SER A 1 461 ? -9.395 -8.710 56.832 1.00 85.80 ? 462 SER A CA 1 ATOM 3486 C C . SER A 1 461 ? -10.449 -8.812 55.719 1.00 85.32 ? 462 SER A C 1 ATOM 3487 O O . SER A 1 461 ? -10.262 -9.543 54.746 1.00 87.73 ? 462 SER A O 1 ATOM 3488 C CB . SER A 1 461 ? -9.027 -10.104 57.359 1.00 82.23 ? 462 SER A CB 1 ATOM 3489 O OG . SER A 1 461 ? -10.177 -10.890 57.621 1.00 83.48 ? 462 SER A OG 1 ATOM 3490 N N . ARG A 1 462 ? -11.544 -8.073 55.861 1.00 86.20 ? 463 ARG A N 1 ATOM 3491 C CA . ARG A 1 462 ? -12.604 -8.062 54.857 1.00 89.89 ? 463 ARG A CA 1 ATOM 3492 C C . ARG A 1 462 ? -12.731 -6.681 54.229 1.00 91.88 ? 463 ARG A C 1 ATOM 3493 O O . ARG A 1 462 ? -12.405 -5.673 54.858 1.00 97.15 ? 463 ARG A O 1 ATOM 3494 C CB . ARG A 1 462 ? -13.931 -8.499 55.473 1.00 87.11 ? 463 ARG A CB 1 ATOM 3495 C CG . ARG A 1 462 ? -13.885 -9.914 56.000 1.00 85.44 ? 463 ARG A CG 1 ATOM 3496 C CD . ARG A 1 462 ? -15.193 -10.336 56.643 1.00 80.44 ? 463 ARG A CD 1 ATOM 3497 N NE . ARG A 1 462 ? -15.154 -11.751 57.004 1.00 86.77 ? 463 ARG A NE 1 ATOM 3498 C CZ . ARG A 1 462 ? -15.248 -12.744 56.122 1.00 88.05 ? 463 ARG A CZ 1 ATOM 3499 N NH1 . ARG A 1 462 ? -15.392 -12.472 54.831 1.00 97.52 ? 463 ARG A NH1 1 ATOM 3500 N NH2 . ARG A 1 462 ? -15.195 -14.008 56.522 1.00 79.08 ? 463 ARG A NH2 1 ATOM 3501 N N . ASN A 1 463 ? -13.227 -6.638 52.997 1.00 86.35 ? 464 ASN A N 1 ATOM 3502 C CA . ASN A 1 463 ? -13.140 -5.430 52.181 1.00 88.95 ? 464 ASN A CA 1 ATOM 3503 C C . ASN A 1 463 ? -14.389 -4.534 52.159 1.00 84.37 ? 464 ASN A C 1 ATOM 3504 O O . ASN A 1 463 ? -14.806 -4.075 51.096 1.00 90.37 ? 464 ASN A O 1 ATOM 3505 C CB . ASN A 1 463 ? -12.727 -5.797 50.745 1.00 81.11 ? 464 ASN A CB 1 ATOM 3506 C CG . ASN A 1 463 ? -11.470 -6.670 50.690 1.00 99.97 ? 464 ASN A CG 1 ATOM 3507 O OD1 . ASN A 1 463 ? -10.522 -6.468 51.451 1.00 98.07 ? 464 ASN A OD1 1 ATOM 3508 N ND2 . ASN A 1 463 ? -11.471 -7.656 49.786 1.00 112.49 ? 464 ASN A ND2 1 ATOM 3509 N N . TYR A 1 464 ? -14.972 -4.256 53.320 1.00 74.56 ? 465 TYR A N 1 ATOM 3510 C CA . TYR A 1 464 ? -16.168 -3.405 53.371 1.00 82.20 ? 465 TYR A CA 1 ATOM 3511 C C . TYR A 1 464 ? -15.824 -1.906 53.346 1.00 77.86 ? 465 TYR A C 1 ATOM 3512 O O . TYR A 1 464 ? -14.746 -1.501 53.784 1.00 77.58 ? 465 TYR A O 1 ATOM 3513 C CB . TYR A 1 464 ? -17.041 -3.741 54.598 1.00 74.95 ? 465 TYR A CB 1 ATOM 3514 C CG . TYR A 1 464 ? -17.739 -5.091 54.522 1.00 76.05 ? 465 TYR A CG 1 ATOM 3515 C CD1 . TYR A 1 464 ? -17.061 -6.269 54.846 1.00 77.58 ? 465 TYR A CD1 1 ATOM 3516 C CD2 . TYR A 1 464 ? -19.074 -5.192 54.131 1.00 67.66 ? 465 TYR A CD2 1 ATOM 3517 C CE1 . TYR A 1 464 ? -17.690 -7.508 54.778 1.00 72.36 ? 465 TYR A CE1 1 ATOM 3518 C CE2 . TYR A 1 464 ? -19.716 -6.432 54.067 1.00 65.20 ? 465 TYR A CE2 1 ATOM 3519 C CZ . TYR A 1 464 ? -19.018 -7.586 54.389 1.00 71.76 ? 465 TYR A CZ 1 ATOM 3520 O OH . TYR A 1 464 ? -19.639 -8.821 54.326 1.00 66.98 ? 465 TYR A OH 1 ATOM 3521 N N . THR A 1 465 ? -16.743 -1.088 52.840 1.00 72.64 ? 466 THR A N 1 ATOM 3522 C CA . THR A 1 465 ? -16.519 0.353 52.786 1.00 72.65 ? 466 THR A CA 1 ATOM 3523 C C . THR A 1 465 ? -16.665 0.999 54.162 1.00 78.29 ? 466 THR A C 1 ATOM 3524 O O . THR A 1 465 ? -16.983 0.333 55.146 1.00 81.85 ? 466 THR A O 1 ATOM 3525 C CB . THR A 1 465 ? -17.474 1.060 51.802 1.00 70.39 ? 466 THR A CB 1 ATOM 3526 O OG1 . THR A 1 465 ? -18.757 1.231 52.413 1.00 77.90 ? 466 THR A OG1 1 ATOM 3527 C CG2 . THR A 1 465 ? -17.619 0.264 50.523 1.00 69.63 ? 466 THR A CG2 1 ATOM 3528 N N . ALA A 1 466 ? -16.434 2.305 54.223 1.00 76.81 ? 467 ALA A N 1 ATOM 3529 C CA . ALA A 1 466 ? -16.505 3.026 55.484 1.00 81.31 ? 467 ALA A CA 1 ATOM 3530 C C . ALA A 1 466 ? -17.944 3.282 55.907 1.00 80.70 ? 467 ALA A C 1 ATOM 3531 O O . ALA A 1 466 ? -18.260 3.251 57.094 1.00 78.24 ? 467 ALA A O 1 ATOM 3532 C CB . ALA A 1 466 ? -15.747 4.336 55.385 1.00 82.83 ? 467 ALA A CB 1 ATOM 3533 N N . GLU A 1 467 ? -18.811 3.544 54.932 1.00 85.57 ? 468 GLU A N 1 ATOM 3534 C CA . GLU A 1 467 ? -20.211 3.870 55.211 1.00 82.91 ? 468 GLU A CA 1 ATOM 3535 C C . GLU A 1 467 ? -20.946 2.635 55.704 1.00 77.75 ? 468 GLU A C 1 ATOM 3536 O O . GLU A 1 467 ? -21.913 2.745 56.456 1.00 67.96 ? 468 GLU A O 1 ATOM 3537 C CB . GLU A 1 467 ? -20.911 4.421 53.965 1.00 78.82 ? 468 GLU A CB 1 ATOM 3538 C CG . GLU A 1 467 ? -20.296 5.689 53.404 1.00 89.47 ? 468 GLU A CG 1 ATOM 3539 C CD . GLU A 1 467 ? -18.983 5.431 52.671 1.00 95.18 ? 468 GLU A CD 1 ATOM 3540 O OE1 . GLU A 1 467 ? -18.656 4.245 52.430 1.00 93.38 ? 468 GLU A OE1 1 ATOM 3541 O OE2 . GLU A 1 467 ? -18.276 6.412 52.346 1.00 90.84 ? 468 GLU A OE2 1 ATOM 3542 N N . GLU A 1 468 ? -20.475 1.469 55.259 1.00 73.59 ? 469 GLU A N 1 ATOM 3543 C CA . GLU A 1 468 ? -21.016 0.184 55.675 1.00 69.91 ? 469 GLU A CA 1 ATOM 3544 C C . GLU A 1 468 ? -20.616 -0.179 57.115 1.00 74.28 ? 469 GLU A C 1 ATOM 3545 O O . GLU A 1 468 ? -21.418 -0.756 57.856 1.00 66.91 ? 469 GLU A O 1 ATOM 3546 C CB . GLU A 1 468 ? -20.590 -0.914 54.698 1.00 69.69 ? 469 GLU A CB 1 ATOM 3547 C CG . GLU A 1 468 ? -21.265 -0.821 53.339 1.00 72.13 ? 469 GLU A CG 1 ATOM 3548 C CD . GLU A 1 468 ? -20.801 -1.899 52.372 1.00 75.71 ? 469 GLU A CD 1 ATOM 3549 O OE1 . GLU A 1 468 ? -19.595 -2.238 52.390 1.00 72.71 ? 469 GLU A OE1 1 ATOM 3550 O OE2 . GLU A 1 468 ? -21.646 -2.409 51.597 1.00 75.56 ? 469 GLU A OE2 1 ATOM 3551 N N . LYS A 1 469 ? -19.384 0.156 57.505 1.00 74.29 ? 470 LYS A N 1 ATOM 3552 C CA . LYS A 1 469 ? -18.956 0.018 58.900 1.00 67.02 ? 470 LYS A CA 1 ATOM 3553 C C . LYS A 1 469 ? -19.867 0.830 59.827 1.00 66.66 ? 470 LYS A C 1 ATOM 3554 O O . LYS A 1 469 ? -20.275 0.344 60.885 1.00 66.00 ? 470 LYS A O 1 ATOM 3555 C CB . LYS A 1 469 ? -17.490 0.433 59.079 1.00 67.21 ? 470 LYS A CB 1 ATOM 3556 C CG . LYS A 1 469 ? -16.464 -0.582 58.554 1.00 70.63 ? 470 LYS A CG 1 ATOM 3557 C CD . LYS A 1 469 ? -15.027 -0.057 58.691 1.00 68.48 ? 470 LYS A CD 1 ATOM 3558 C CE . LYS A 1 469 ? -13.971 -1.154 58.504 1.00 70.92 ? 470 LYS A CE 1 ATOM 3559 N NZ . LYS A 1 469 ? -13.453 -1.282 57.114 1.00 75.34 ? 470 LYS A NZ 1 ATOM 3560 N N . ILE A 1 470 ? -20.199 2.054 59.413 1.00 62.70 ? 471 ILE A N 1 ATOM 3561 C CA . ILE A 1 470 ? -21.096 2.932 60.176 1.00 67.63 ? 471 ILE A CA 1 ATOM 3562 C C . ILE A 1 470 ? -22.515 2.383 60.219 1.00 67.53 ? 471 ILE A C 1 ATOM 3563 O O . ILE A 1 470 ? -23.164 2.361 61.268 1.00 68.65 ? 471 ILE A O 1 ATOM 3564 C CB . ILE A 1 470 ? -21.145 4.349 59.569 1.00 65.95 ? 471 ILE A CB 1 ATOM 3565 C CG1 . ILE A 1 470 ? -19.824 5.082 59.809 1.00 66.28 ? 471 ILE A CG1 1 ATOM 3566 C CG2 . ILE A 1 470 ? -22.314 5.141 60.135 1.00 47.68 ? 471 ILE A CG2 1 ATOM 3567 C CD1 . ILE A 1 470 ? -19.725 6.397 59.069 1.00 64.07 ? 471 ILE A CD1 1 ATOM 3568 N N . PHE A 1 471 ? -22.982 1.946 59.054 1.00 70.04 ? 472 PHE A N 1 ATOM 3569 C CA . PHE A 1 471 ? -24.284 1.314 58.889 1.00 65.32 ? 472 PHE A CA 1 ATOM 3570 C C . PHE A 1 471 ? -24.449 0.105 59.820 1.00 64.61 ? 472 PHE A C 1 ATOM 3571 O O . PHE A 1 471 ? -25.456 -0.018 60.514 1.00 67.91 ? 472 PHE A O 1 ATOM 3572 C CB . PHE A 1 471 ? -24.457 0.898 57.419 1.00 68.56 ? 472 PHE A CB 1 ATOM 3573 C CG . PHE A 1 471 ? -25.771 0.239 57.123 1.00 65.91 ? 472 PHE A CG 1 ATOM 3574 C CD1 . PHE A 1 471 ? -26.961 0.820 57.537 1.00 62.76 ? 472 PHE A CD1 1 ATOM 3575 C CD2 . PHE A 1 471 ? -25.817 -0.961 56.432 1.00 60.04 ? 472 PHE A CD2 1 ATOM 3576 C CE1 . PHE A 1 471 ? -28.170 0.216 57.270 1.00 66.76 ? 472 PHE A CE1 1 ATOM 3577 C CE2 . PHE A 1 471 ? -27.027 -1.573 56.160 1.00 62.97 ? 472 PHE A CE2 1 ATOM 3578 C CZ . PHE A 1 471 ? -28.206 -0.985 56.579 1.00 65.03 ? 472 PHE A CZ 1 ATOM 3579 N N . ALA A 1 472 ? -23.448 -0.771 59.835 1.00 62.36 ? 473 ALA A N 1 ATOM 3580 C CA . ALA A 1 472 ? -23.450 -1.956 60.684 1.00 62.57 ? 473 ALA A CA 1 ATOM 3581 C C . ALA A 1 472 ? -23.544 -1.610 62.181 1.00 70.61 ? 473 ALA A C 1 ATOM 3582 O O . ALA A 1 472 ? -24.282 -2.251 62.939 1.00 63.61 ? 473 ALA A O 1 ATOM 3583 C CB . ALA A 1 472 ? -22.214 -2.804 60.406 1.00 60.45 ? 473 ALA A CB 1 ATOM 3584 N N . GLN A 1 473 ? -22.800 -0.590 62.599 1.00 72.36 ? 474 GLN A N 1 ATOM 3585 C CA . GLN A 1 473 ? -22.826 -0.155 63.991 1.00 61.86 ? 474 GLN A CA 1 ATOM 3586 C C . GLN A 1 473 ? -24.174 0.467 64.314 1.00 60.13 ? 474 GLN A C 1 ATOM 3587 O O . GLN A 1 473 ? -24.680 0.329 65.417 1.00 66.40 ? 474 GLN A O 1 ATOM 3588 C CB . GLN A 1 473 ? -21.686 0.824 64.276 1.00 59.09 ? 474 GLN A CB 1 ATOM 3589 C CG . GLN A 1 473 ? -20.305 0.169 64.292 1.00 65.25 ? 474 GLN A CG 1 ATOM 3590 C CD . GLN A 1 473 ? -19.168 1.175 64.155 1.00 73.89 ? 474 GLN A CD 1 ATOM 3591 O OE1 . GLN A 1 473 ? -19.340 2.259 63.589 1.00 71.94 ? 474 GLN A OE1 1 ATOM 3592 N NE2 . GLN A 1 473 ? -17.998 0.815 64.669 1.00 69.16 ? 474 GLN A NE2 1 ATOM 3593 N N . ARG A 1 474 ? -24.759 1.138 63.334 1.00 65.77 ? 475 ARG A N 1 ATOM 3594 C CA . ARG A 1 474 ? -26.094 1.700 63.480 1.00 65.17 ? 475 ARG A CA 1 ATOM 3595 C C . ARG A 1 474 ? -27.103 0.572 63.697 1.00 67.75 ? 475 ARG A C 1 ATOM 3596 O O . ARG A 1 474 ? -27.998 0.683 64.538 1.00 65.79 ? 475 ARG A O 1 ATOM 3597 C CB . ARG A 1 474 ? -26.444 2.506 62.230 1.00 70.06 ? 475 ARG A CB 1 ATOM 3598 C CG . ARG A 1 474 ? -27.598 3.476 62.387 1.00 75.59 ? 475 ARG A CG 1 ATOM 3599 C CD . ARG A 1 474 ? -27.625 4.450 61.204 1.00 68.82 ? 475 ARG A CD 1 ATOM 3600 N NE . ARG A 1 474 ? -28.967 4.547 60.648 1.00 73.42 ? 475 ARG A NE 1 ATOM 3601 C CZ . ARG A 1 474 ? -29.335 3.991 59.500 1.00 73.49 ? 475 ARG A CZ 1 ATOM 3602 N NH1 . ARG A 1 474 ? -28.444 3.321 58.778 1.00 69.61 ? 475 ARG A NH1 1 ATOM 3603 N NH2 . ARG A 1 474 ? -30.585 4.119 59.067 1.00 75.05 ? 475 ARG A NH2 1 ATOM 3604 N N . LEU A 1 475 ? -26.937 -0.524 62.955 1.00 63.93 ? 476 LEU A N 1 ATOM 3605 C CA . LEU A 1 475 ? -27.826 -1.674 63.089 1.00 64.57 ? 476 LEU A CA 1 ATOM 3606 C C . LEU A 1 475 ? -27.656 -2.420 64.421 1.00 64.56 ? 476 LEU A C 1 ATOM 3607 O O . LEU A 1 475 ? -28.638 -2.747 65.086 1.00 59.91 ? 476 LEU A O 1 ATOM 3608 C CB . LEU A 1 475 ? -27.635 -2.641 61.927 1.00 66.21 ? 476 LEU A CB 1 ATOM 3609 C CG . LEU A 1 475 ? -28.049 -2.157 60.534 1.00 63.78 ? 476 LEU A CG 1 ATOM 3610 C CD1 . LEU A 1 475 ? -27.787 -3.247 59.505 1.00 60.83 ? 476 LEU A CD1 1 ATOM 3611 C CD2 . LEU A 1 475 ? -29.502 -1.753 60.522 1.00 65.97 ? 476 LEU A CD2 1 ATOM 3612 N N . MET A 1 476 ? -26.410 -2.689 64.798 1.00 67.43 ? 477 MET A N 1 ATOM 3613 C CA . MET A 1 476 ? -26.108 -3.318 66.081 1.00 58.26 ? 477 MET A CA 1 ATOM 3614 C C . MET A 1 476 ? -26.705 -2.524 67.242 1.00 61.48 ? 477 MET A C 1 ATOM 3615 O O . MET A 1 476 ? -27.142 -3.099 68.234 1.00 60.72 ? 477 MET A O 1 ATOM 3616 C CB . MET A 1 476 ? -24.601 -3.496 66.254 1.00 51.95 ? 477 MET A CB 1 ATOM 3617 C CG . MET A 1 476 ? -24.008 -4.524 65.316 1.00 58.55 ? 477 MET A CG 1 ATOM 3618 S SD . MET A 1 476 ? -22.280 -4.957 65.625 1.00 69.63 ? 477 MET A SD 1 ATOM 3619 C CE . MET A 1 476 ? -21.497 -3.354 65.542 1.00 67.71 ? 477 MET A CE 1 ATOM 3620 N N . ARG A 1 477 ? -26.760 -1.205 67.100 1.00 61.56 ? 478 ARG A N 1 ATOM 3621 C CA . ARG A 1 477 ? -27.398 -0.375 68.108 1.00 60.63 ? 478 ARG A CA 1 ATOM 3622 C C . ARG A 1 477 ? -28.900 -0.608 68.155 1.00 64.39 ? 478 ARG A C 1 ATOM 3623 O O . ARG A 1 477 ? -29.465 -0.747 69.233 1.00 66.90 ? 478 ARG A O 1 ATOM 3624 C CB . ARG A 1 477 ? -27.123 1.107 67.862 1.00 63.36 ? 478 ARG A CB 1 ATOM 3625 C CG . ARG A 1 477 ? -27.841 2.020 68.856 1.00 72.52 ? 478 ARG A CG 1 ATOM 3626 C CD . ARG A 1 477 ? -27.085 2.105 70.166 1.00 78.02 ? 478 ARG A CD 1 ATOM 3627 N NE . ARG A 1 477 ? -25.698 2.475 69.912 1.00 82.41 ? 478 ARG A NE 1 ATOM 3628 C CZ . ARG A 1 477 ? -24.777 2.646 70.849 1.00 83.83 ? 478 ARG A CZ 1 ATOM 3629 N NH1 . ARG A 1 477 ? -25.094 2.492 72.134 1.00 95.25 ? 478 ARG A NH1 1 ATOM 3630 N NH2 . ARG A 1 477 ? -23.537 2.970 70.496 1.00 70.97 ? 478 ARG A NH2 1 ATOM 3631 N N . TYR A 1 478 ? -29.545 -0.622 66.989 1.00 62.21 ? 479 TYR A N 1 ATOM 3632 C CA . TYR A 1 478 ? -30.982 -0.901 66.895 1.00 64.46 ? 479 TYR A CA 1 ATOM 3633 C C . TYR A 1 478 ? -31.352 -2.235 67.552 1.00 61.08 ? 479 TYR A C 1 ATOM 3634 O O . TYR A 1 478 ? -32.333 -2.321 68.284 1.00 56.65 ? 479 TYR A O 1 ATOM 3635 C CB . TYR A 1 478 ? -31.428 -0.943 65.427 1.00 64.98 ? 479 TYR A CB 1 ATOM 3636 C CG . TYR A 1 478 ? -31.563 0.403 64.745 1.00 65.25 ? 479 TYR A CG 1 ATOM 3637 C CD1 . TYR A 1 478 ? -32.082 1.501 65.418 1.00 59.89 ? 479 TYR A CD1 1 ATOM 3638 C CD2 . TYR A 1 478 ? -31.183 0.567 63.412 1.00 62.88 ? 479 TYR A CD2 1 ATOM 3639 C CE1 . TYR A 1 478 ? -32.214 2.731 64.788 1.00 62.89 ? 479 TYR A CE1 1 ATOM 3640 C CE2 . TYR A 1 478 ? -31.306 1.793 62.772 1.00 64.80 ? 479 TYR A CE2 1 ATOM 3641 C CZ . TYR A 1 478 ? -31.823 2.875 63.459 1.00 68.06 ? 479 TYR A CZ 1 ATOM 3642 O OH . TYR A 1 478 ? -31.942 4.098 62.822 1.00 64.56 ? 479 TYR A OH 1 ATOM 3643 N N . TRP A 1 479 ? -30.566 -3.272 67.265 1.00 55.78 ? 480 TRP A N 1 ATOM 3644 C CA . TRP A 1 479 ? -30.817 -4.605 67.792 1.00 54.18 ? 480 TRP A CA 1 ATOM 3645 C C . TRP A 1 479 ? -30.537 -4.665 69.300 1.00 62.88 ? 480 TRP A C 1 ATOM 3646 O O . TRP A 1 479 ? -31.328 -5.226 70.065 1.00 57.16 ? 480 TRP A O 1 ATOM 3647 C CB . TRP A 1 479 ? -30.001 -5.657 67.026 1.00 57.37 ? 480 TRP A CB 1 ATOM 3648 C CG . TRP A 1 479 ? -30.776 -6.418 65.938 1.00 62.77 ? 480 TRP A CG 1 ATOM 3649 C CD1 . TRP A 1 479 ? -31.025 -7.764 65.901 1.00 61.60 ? 480 TRP A CD1 1 ATOM 3650 C CD2 . TRP A 1 479 ? -31.384 -5.872 64.752 1.00 61.02 ? 480 TRP A CD2 1 ATOM 3651 N NE1 . TRP A 1 479 ? -31.749 -8.088 64.774 1.00 53.24 ? 480 TRP A NE1 1 ATOM 3652 C CE2 . TRP A 1 479 ? -31.981 -6.946 64.053 1.00 64.14 ? 480 TRP A CE2 1 ATOM 3653 C CE3 . TRP A 1 479 ? -31.476 -4.585 64.209 1.00 65.60 ? 480 TRP A CE3 1 ATOM 3654 C CZ2 . TRP A 1 479 ? -32.661 -6.767 62.834 1.00 64.68 ? 480 TRP A CZ2 1 ATOM 3655 C CZ3 . TRP A 1 479 ? -32.151 -4.410 62.993 1.00 61.89 ? 480 TRP A CZ3 1 ATOM 3656 C CH2 . TRP A 1 479 ? -32.736 -5.496 62.328 1.00 57.69 ? 480 TRP A CH2 1 ATOM 3657 N N . ALA A 1 480 ? -29.433 -4.066 69.735 1.00 62.40 ? 481 ALA A N 1 ATOM 3658 C CA . ALA A 1 480 ? -29.114 -4.038 71.165 1.00 62.69 ? 481 ALA A CA 1 ATOM 3659 C C . ALA A 1 480 ? -30.098 -3.197 72.008 1.00 63.42 ? 481 ALA A C 1 ATOM 3660 O O . ALA A 1 480 ? -30.414 -3.563 73.157 1.00 55.27 ? 481 ALA A O 1 ATOM 3661 C CB . ALA A 1 480 ? -27.683 -3.587 71.388 1.00 62.96 ? 481 ALA A CB 1 ATOM 3662 N N . ASN A 1 481 ? -30.585 -2.087 71.444 1.00 59.32 ? 482 ASN A N 1 ATOM 3663 C CA . ASN A 1 481 ? -31.599 -1.287 72.130 1.00 58.29 ? 482 ASN A CA 1 ATOM 3664 C C . ASN A 1 481 ? -32.874 -2.082 72.352 1.00 60.54 ? 482 ASN A C 1 ATOM 3665 O O . ASN A 1 481 ? -33.498 -1.995 73.413 1.00 57.56 ? 482 ASN A O 1 ATOM 3666 C CB . ASN A 1 481 ? -31.916 -0.002 71.375 1.00 62.11 ? 482 ASN A CB 1 ATOM 3667 C CG . ASN A 1 481 ? -30.788 0.997 71.436 1.00 67.76 ? 482 ASN A CG 1 ATOM 3668 O OD1 . ASN A 1 481 ? -29.831 0.821 72.188 1.00 67.37 ? 482 ASN A OD1 1 ATOM 3669 N ND2 . ASN A 1 481 ? -30.893 2.058 70.645 1.00 76.15 ? 482 ASN A ND2 1 ATOM 3670 N N . PHE A 1 482 ? -33.252 -2.862 71.345 1.00 56.28 ? 483 PHE A N 1 ATOM 3671 C CA . PHE A 1 482 ? -34.408 -3.745 71.454 1.00 56.08 ? 483 PHE A CA 1 ATOM 3672 C C . PHE A 1 482 ? -34.243 -4.822 72.550 1.00 52.99 ? 483 PHE A C 1 ATOM 3673 O O . PHE A 1 482 ? -35.180 -5.107 73.301 1.00 51.81 ? 483 PHE A O 1 ATOM 3674 C CB . PHE A 1 482 ? -34.724 -4.394 70.100 1.00 53.04 ? 483 PHE A CB 1 ATOM 3675 C CG . PHE A 1 482 ? -35.933 -5.274 70.128 1.00 44.22 ? 483 PHE A CG 1 ATOM 3676 C CD1 . PHE A 1 482 ? -37.203 -4.722 70.145 1.00 46.45 ? 483 PHE A CD1 1 ATOM 3677 C CD2 . PHE A 1 482 ? -35.804 -6.649 70.153 1.00 42.56 ? 483 PHE A CD2 1 ATOM 3678 C CE1 . PHE A 1 482 ? -38.321 -5.525 70.176 1.00 45.74 ? 483 PHE A CE1 1 ATOM 3679 C CE2 . PHE A 1 482 ? -36.919 -7.462 70.202 1.00 47.23 ? 483 PHE A CE2 1 ATOM 3680 C CZ . PHE A 1 482 ? -38.177 -6.901 70.209 1.00 49.70 ? 483 PHE A CZ 1 ATOM 3681 N N . ALA A 1 483 ? -33.058 -5.420 72.631 1.00 52.54 ? 484 ALA A N 1 ATOM 3682 C CA . ALA A 1 483 ? -32.772 -6.438 73.646 1.00 52.96 ? 484 ALA A CA 1 ATOM 3683 C C . ALA A 1 483 ? -32.800 -5.869 75.082 1.00 58.22 ? 484 ALA A C 1 ATOM 3684 O O . ALA A 1 483 ? -33.334 -6.507 75.991 1.00 62.98 ? 484 ALA A O 1 ATOM 3685 C CB . ALA A 1 483 ? -31.436 -7.123 73.359 1.00 43.00 ? 484 ALA A CB 1 ATOM 3686 N N . ARG A 1 484 ? -32.245 -4.671 75.271 1.00 56.43 ? 485 ARG A N 1 ATOM 3687 C CA . ARG A 1 484 ? -32.238 -4.017 76.586 1.00 62.43 ? 485 ARG A CA 1 ATOM 3688 C C . ARG A 1 484 ? -33.622 -3.547 77.014 1.00 60.86 ? 485 ARG A C 1 ATOM 3689 O O . ARG A 1 484 ? -34.020 -3.745 78.169 1.00 64.09 ? 485 ARG A O 1 ATOM 3690 C CB . ARG A 1 484 ? -31.247 -2.836 76.635 1.00 54.25 ? 485 ARG A CB 1 ATOM 3691 C CG . ARG A 1 484 ? -29.775 -3.255 76.568 1.00 53.35 ? 485 ARG A CG 1 ATOM 3692 C CD . ARG A 1 484 ? -28.834 -2.065 76.608 1.00 47.18 ? 485 ARG A CD 1 ATOM 3693 N NE . ARG A 1 484 ? -28.819 -1.345 75.342 1.00 58.52 ? 485 ARG A NE 1 ATOM 3694 C CZ . ARG A 1 484 ? -27.878 -1.493 74.409 1.00 63.33 ? 485 ARG A CZ 1 ATOM 3695 N NH1 . ARG A 1 484 ? -26.859 -2.329 74.607 1.00 57.76 ? 485 ARG A NH1 1 ATOM 3696 N NH2 . ARG A 1 484 ? -27.952 -0.802 73.273 1.00 56.22 ? 485 ARG A NH2 1 ATOM 3697 N N . THR A 1 485 ? -34.360 -2.949 76.083 1.00 55.65 ? 486 THR A N 1 ATOM 3698 C CA . THR A 1 485 ? -35.571 -2.209 76.436 1.00 57.96 ? 486 THR A CA 1 ATOM 3699 C C . THR A 1 485 ? -36.859 -2.654 75.722 1.00 58.01 ? 486 THR A C 1 ATOM 3700 O O . THR A 1 485 ? -37.955 -2.340 76.175 1.00 56.81 ? 486 THR A O 1 ATOM 3701 C CB . THR A 1 485 ? -35.380 -0.717 76.147 1.00 62.03 ? 486 THR A CB 1 ATOM 3702 O OG1 . THR A 1 485 ? -35.693 -0.466 74.773 1.00 61.02 ? 486 THR A OG1 1 ATOM 3703 C CG2 . THR A 1 485 ? -33.928 -0.285 76.421 1.00 55.53 ? 486 THR A CG2 1 ATOM 3704 N N . GLY A 1 486 ? -36.731 -3.368 74.604 1.00 62.43 ? 487 GLY A N 1 ATOM 3705 C CA . GLY A 1 486 ? -37.886 -3.766 73.806 1.00 53.29 ? 487 GLY A CA 1 ATOM 3706 C C . GLY A 1 486 ? -38.296 -2.655 72.854 1.00 58.13 ? 487 GLY A C 1 ATOM 3707 O O . GLY A 1 486 ? -39.464 -2.532 72.467 1.00 61.58 ? 487 GLY A O 1 ATOM 3708 N N . ASP A 1 487 ? -37.312 -1.844 72.478 1.00 56.87 ? 488 ASP A N 1 ATOM 3709 C CA . ASP A 1 487 ? -37.528 -0.657 71.678 1.00 56.36 ? 488 ASP A CA 1 ATOM 3710 C C . ASP A 1 487 ? -36.188 -0.291 71.046 1.00 65.94 ? 488 ASP A C 1 ATOM 3711 O O . ASP A 1 487 ? -35.231 0.035 71.755 1.00 67.88 ? 488 ASP A O 1 ATOM 3712 C CB . ASP A 1 487 ? -38.058 0.482 72.551 1.00 54.47 ? 488 ASP A CB 1 ATOM 3713 C CG . ASP A 1 487 ? -38.509 1.693 71.739 1.00 67.68 ? 488 ASP A CG 1 ATOM 3714 O OD1 . ASP A 1 487 ? -38.049 1.869 70.595 1.00 69.83 ? 488 ASP A OD1 1 ATOM 3715 O OD2 . ASP A 1 487 ? -39.328 2.484 72.247 1.00 65.93 ? 488 ASP A OD2 1 ATOM 3716 N N . PRO A 1 488 ? -36.120 -0.350 69.703 1.00 69.58 ? 489 PRO A N 1 ATOM 3717 C CA . PRO A 1 488 ? -34.900 -0.146 68.911 1.00 70.26 ? 489 PRO A CA 1 ATOM 3718 C C . PRO A 1 488 ? -34.522 1.318 68.880 1.00 71.41 ? 489 PRO A C 1 ATOM 3719 O O . PRO A 1 488 ? -33.390 1.672 68.536 1.00 68.79 ? 489 PRO A O 1 ATOM 3720 C CB . PRO A 1 488 ? -35.322 -0.567 67.495 1.00 59.74 ? 489 PRO A CB 1 ATOM 3721 C CG . PRO A 1 488 ? -36.642 -1.226 67.646 1.00 65.34 ? 489 PRO A CG 1 ATOM 3722 C CD . PRO A 1 488 ? -37.279 -0.620 68.842 1.00 61.04 ? 489 PRO A CD 1 ATOM 3723 N N . ASN A 1 489 ? -35.492 2.157 69.225 1.00 72.93 ? 490 ASN A N 1 ATOM 3724 C CA . ASN A 1 489 ? -35.324 3.594 69.157 1.00 77.78 ? 490 ASN A CA 1 ATOM 3725 C C . ASN A 1 489 ? -34.216 4.105 70.049 1.00 94.66 ? 490 ASN A C 1 ATOM 3726 O O . ASN A 1 489 ? -34.179 3.821 71.257 1.00 87.93 ? 490 ASN A O 1 ATOM 3727 C CB . ASN A 1 489 ? -36.632 4.306 69.470 1.00 77.20 ? 490 ASN A CB 1 ATOM 3728 C CG . ASN A 1 489 ? -37.489 4.475 68.245 1.00 74.91 ? 490 ASN A CG 1 ATOM 3729 O OD1 . ASN A 1 489 ? -37.035 5.025 67.246 1.00 78.66 ? 490 ASN A OD1 1 ATOM 3730 N ND2 . ASN A 1 489 ? -38.725 3.985 68.298 1.00 73.38 ? 490 ASN A ND2 1 ATOM 3731 N N . GLU A 1 490 ? -33.304 4.839 69.412 1.00 106.81 ? 491 GLU A N 1 ATOM 3732 C CA . GLU A 1 490 ? -32.214 5.526 70.083 1.00 112.39 ? 491 GLU A CA 1 ATOM 3733 C C . GLU A 1 490 ? -32.771 6.785 70.736 1.00 120.93 ? 491 GLU A C 1 ATOM 3734 O O . GLU A 1 490 ? -33.056 7.772 70.042 1.00 115.33 ? 491 GLU A O 1 ATOM 3735 C CB . GLU A 1 490 ? -31.122 5.896 69.072 1.00 108.13 ? 491 GLU A CB 1 ATOM 3736 C CG . GLU A 1 490 ? -29.868 6.485 69.698 1.00 111.91 ? 491 GLU A CG 1 ATOM 3737 C CD . GLU A 1 490 ? -28.982 5.431 70.346 1.00 107.45 ? 491 GLU A CD 1 ATOM 3738 O OE1 . GLU A 1 490 ? -28.002 5.018 69.688 1.00 96.92 ? 491 GLU A OE1 1 ATOM 3739 O OE2 . GLU A 1 490 ? -29.255 5.023 71.503 1.00 99.71 ? 491 GLU A OE2 1 ATOM 3740 N N . PRO A 1 491 ? -32.945 6.750 72.073 1.00 124.62 ? 492 PRO A N 1 ATOM 3741 C CA . PRO A 1 491 ? -33.508 7.914 72.769 1.00 130.30 ? 492 PRO A CA 1 ATOM 3742 C C . PRO A 1 491 ? -32.496 9.066 72.833 1.00 133.18 ? 492 PRO A C 1 ATOM 3743 O O . PRO A 1 491 ? -31.442 8.889 73.447 1.00 130.72 ? 492 PRO A O 1 ATOM 3744 C CB . PRO A 1 491 ? -33.816 7.365 74.170 1.00 126.31 ? 492 PRO A CB 1 ATOM 3745 C CG . PRO A 1 491 ? -32.882 6.206 74.355 1.00 117.87 ? 492 PRO A CG 1 ATOM 3746 C CD . PRO A 1 491 ? -32.587 5.652 72.996 1.00 114.02 ? 492 PRO A CD 1 ATOM 3747 N N . ARG A 1 492 ? -32.786 10.216 72.217 1.00 133.31 ? 493 ARG A N 1 ATOM 3748 C CA . ARG A 1 492 ? -34.042 10.498 71.518 1.00 132.07 ? 493 ARG A CA 1 ATOM 3749 C C . ARG A 1 492 ? -33.727 10.947 70.079 1.00 128.42 ? 493 ARG A C 1 ATOM 3750 O O . ARG A 1 492 ? -32.716 10.527 69.507 1.00 120.99 ? 493 ARG A O 1 ATOM 3751 C CB . ARG A 1 492 ? -34.799 11.607 72.268 1.00 131.58 ? 493 ARG A CB 1 ATOM 3752 C CG . ARG A 1 492 ? -36.325 11.551 72.200 1.00 125.91 ? 493 ARG A CG 1 ATOM 3753 C CD . ARG A 1 492 ? -36.916 10.810 73.386 1.00 123.13 ? 493 ARG A CD 1 ATOM 3754 N NE . ARG A 1 492 ? -36.572 9.392 73.367 1.00 131.35 ? 493 ARG A NE 1 ATOM 3755 C CZ . ARG A 1 492 ? -37.375 8.419 73.788 1.00 133.16 ? 493 ARG A CZ 1 ATOM 3756 N NH1 . ARG A 1 492 ? -38.579 8.709 74.264 1.00 128.69 ? 493 ARG A NH1 1 ATOM 3757 N NH2 . ARG A 1 492 ? -36.978 7.155 73.728 1.00 128.76 ? 493 ARG A NH2 1 ATOM 3758 N N . ASP A 1 493 ? -34.603 11.788 69.517 1.00 127.82 ? 494 ASP A N 1 ATOM 3759 C CA . ASP A 1 493 ? -34.414 12.499 68.231 1.00 128.44 ? 494 ASP A CA 1 ATOM 3760 C C . ASP A 1 493 ? -33.663 11.769 67.102 1.00 130.65 ? 494 ASP A C 1 ATOM 3761 O O . ASP A 1 493 ? -33.380 12.351 66.044 1.00 112.83 ? 494 ASP A O 1 ATOM 3762 C CB . ASP A 1 493 ? -33.779 13.874 68.465 1.00 125.93 ? 494 ASP A CB 1 ATOM 3763 C CG . ASP A 1 493 ? -32.361 13.779 68.992 1.00 132.84 ? 494 ASP A CG 1 ATOM 3764 O OD1 . ASP A 1 493 ? -32.187 13.761 70.232 1.00 130.73 ? 494 ASP A OD1 1 ATOM 3765 O OD2 . ASP A 1 493 ? -31.423 13.720 68.164 1.00 130.44 ? 494 ASP A OD2 1 ATOM 3766 N N . PRO A 1 497 ? -34.528 10.518 63.102 1.00 91.86 ? 498 PRO A N 1 ATOM 3767 C CA . PRO A 1 497 ? -35.860 10.004 62.753 1.00 89.16 ? 498 PRO A CA 1 ATOM 3768 C C . PRO A 1 497 ? -36.284 8.894 63.713 1.00 88.13 ? 498 PRO A C 1 ATOM 3769 O O . PRO A 1 497 ? -35.428 8.135 64.178 1.00 84.62 ? 498 PRO A O 1 ATOM 3770 C CB . PRO A 1 497 ? -35.663 9.431 61.341 1.00 84.52 ? 498 PRO A CB 1 ATOM 3771 C CG . PRO A 1 497 ? -34.463 10.134 60.793 1.00 82.56 ? 498 PRO A CG 1 ATOM 3772 C CD . PRO A 1 497 ? -33.572 10.386 61.989 1.00 94.92 ? 498 PRO A CD 1 ATOM 3773 N N . GLN A 1 498 ? -37.581 8.801 63.999 1.00 80.23 ? 499 GLN A N 1 ATOM 3774 C CA . GLN A 1 498 ? -38.085 7.801 64.937 1.00 78.76 ? 499 GLN A CA 1 ATOM 3775 C C . GLN A 1 498 ? -38.730 6.603 64.232 1.00 78.34 ? 499 GLN A C 1 ATOM 3776 O O . GLN A 1 498 ? -39.373 6.754 63.199 1.00 73.94 ? 499 GLN A O 1 ATOM 3777 C CB . GLN A 1 498 ? -39.070 8.432 65.930 1.00 81.99 ? 499 GLN A CB 1 ATOM 3778 C CG . GLN A 1 498 ? -38.423 9.402 66.917 1.00 85.98 ? 499 GLN A CG 1 ATOM 3779 C CD . GLN A 1 498 ? -37.465 8.716 67.886 1.00 93.86 ? 499 GLN A CD 1 ATOM 3780 O OE1 . GLN A 1 498 ? -37.851 7.794 68.613 1.00 90.43 ? 499 GLN A OE1 1 ATOM 3781 N NE2 . GLN A 1 498 ? -36.212 9.166 67.903 1.00 96.52 ? 499 GLN A NE2 1 ATOM 3782 N N . TRP A 1 499 ? -38.548 5.417 64.810 1.00 75.11 ? 500 TRP A N 1 ATOM 3783 C CA . TRP A 1 499 ? -39.106 4.165 64.293 1.00 62.54 ? 500 TRP A CA 1 ATOM 3784 C C . TRP A 1 499 ? -40.404 3.818 65.039 1.00 63.72 ? 500 TRP A C 1 ATOM 3785 O O . TRP A 1 499 ? -40.372 3.445 66.214 1.00 62.96 ? 500 TRP A O 1 ATOM 3786 C CB . TRP A 1 499 ? -38.055 3.061 64.453 1.00 55.67 ? 500 TRP A CB 1 ATOM 3787 C CG . TRP A 1 499 ? -38.398 1.680 63.940 1.00 60.22 ? 500 TRP A CG 1 ATOM 3788 C CD1 . TRP A 1 499 ? -39.629 1.194 63.591 1.00 58.17 ? 500 TRP A CD1 1 ATOM 3789 C CD2 . TRP A 1 499 ? -37.472 0.605 63.735 1.00 55.81 ? 500 TRP A CD2 1 ATOM 3790 N NE1 . TRP A 1 499 ? -39.521 -0.115 63.183 1.00 56.23 ? 500 TRP A NE1 1 ATOM 3791 C CE2 . TRP A 1 499 ? -38.207 -0.498 63.263 1.00 55.44 ? 500 TRP A CE2 1 ATOM 3792 C CE3 . TRP A 1 499 ? -36.089 0.469 63.914 1.00 53.96 ? 500 TRP A CE3 1 ATOM 3793 C CZ2 . TRP A 1 499 ? -37.606 -1.720 62.961 1.00 60.41 ? 500 TRP A CZ2 1 ATOM 3794 C CZ3 . TRP A 1 499 ? -35.491 -0.738 63.619 1.00 49.83 ? 500 TRP A CZ3 1 ATOM 3795 C CH2 . TRP A 1 499 ? -36.248 -1.820 63.144 1.00 62.64 ? 500 TRP A CH2 1 ATOM 3796 N N . PRO A 1 500 ? -41.557 3.954 64.356 1.00 62.13 ? 501 PRO A N 1 ATOM 3797 C CA . PRO A 1 500 ? -42.870 3.697 64.956 1.00 57.72 ? 501 PRO A CA 1 ATOM 3798 C C . PRO A 1 500 ? -43.218 2.219 64.971 1.00 62.67 ? 501 PRO A C 1 ATOM 3799 O O . PRO A 1 500 ? -42.721 1.454 64.140 1.00 55.79 ? 501 PRO A O 1 ATOM 3800 C CB . PRO A 1 500 ? -43.844 4.430 64.024 1.00 57.72 ? 501 PRO A CB 1 ATOM 3801 C CG . PRO A 1 500 ? -43.027 4.925 62.848 1.00 63.49 ? 501 PRO A CG 1 ATOM 3802 C CD . PRO A 1 500 ? -41.674 4.289 62.927 1.00 68.95 ? 501 PRO A CD 1 ATOM 3803 N N . PRO A 1 501 ? -44.051 1.811 65.935 1.00 66.00 ? 502 PRO A N 1 ATOM 3804 C CA . PRO A 1 501 ? -44.557 0.439 65.988 1.00 62.72 ? 502 PRO A CA 1 ATOM 3805 C C . PRO A 1 501 ? -45.353 0.100 64.733 1.00 65.92 ? 502 PRO A C 1 ATOM 3806 O O . PRO A 1 501 ? -45.861 0.996 64.062 1.00 67.05 ? 502 PRO A O 1 ATOM 3807 C CB . PRO A 1 501 ? -45.488 0.457 67.200 1.00 63.32 ? 502 PRO A CB 1 ATOM 3808 C CG . PRO A 1 501 ? -44.962 1.548 68.057 1.00 59.24 ? 502 PRO A CG 1 ATOM 3809 C CD . PRO A 1 501 ? -44.411 2.584 67.136 1.00 61.14 ? 502 PRO A CD 1 ATOM 3810 N N . TYR A 1 502 ? -45.441 -1.188 64.428 1.00 63.90 ? 503 TYR A N 1 ATOM 3811 C CA . TYR A 1 502 ? -46.271 -1.682 63.351 1.00 59.76 ? 503 TYR A CA 1 ATOM 3812 C C . TYR A 1 502 ? -47.637 -2.055 63.911 1.00 61.92 ? 503 TYR A C 1 ATOM 3813 O O . TYR A 1 502 ? -47.735 -2.735 64.931 1.00 66.14 ? 503 TYR A O 1 ATOM 3814 C CB . TYR A 1 502 ? -45.596 -2.896 62.705 1.00 63.25 ? 503 TYR A CB 1 ATOM 3815 C CG . TYR A 1 502 ? -46.368 -3.539 61.573 1.00 62.93 ? 503 TYR A CG 1 ATOM 3816 C CD1 . TYR A 1 502 ? -47.265 -4.571 61.816 1.00 59.15 ? 503 TYR A CD1 1 ATOM 3817 C CD2 . TYR A 1 502 ? -46.182 -3.129 60.254 1.00 67.14 ? 503 TYR A CD2 1 ATOM 3818 C CE1 . TYR A 1 502 ? -47.964 -5.170 60.784 1.00 64.04 ? 503 TYR A CE1 1 ATOM 3819 C CE2 . TYR A 1 502 ? -46.877 -3.729 59.206 1.00 59.97 ? 503 TYR A CE2 1 ATOM 3820 C CZ . TYR A 1 502 ? -47.769 -4.746 59.475 1.00 65.98 ? 503 TYR A CZ 1 ATOM 3821 O OH . TYR A 1 502 ? -48.472 -5.346 58.443 1.00 65.13 ? 503 TYR A OH 1 ATOM 3822 N N . THR A 1 503 ? -48.692 -1.597 63.249 1.00 64.84 ? 504 THR A N 1 ATOM 3823 C CA . THR A 1 503 ? -50.061 -1.953 63.623 1.00 66.34 ? 504 THR A CA 1 ATOM 3824 C C . THR A 1 503 ? -50.808 -2.457 62.384 1.00 71.25 ? 504 THR A C 1 ATOM 3825 O O . THR A 1 503 ? -50.356 -2.247 61.258 1.00 70.87 ? 504 THR A O 1 ATOM 3826 C CB . THR A 1 503 ? -50.785 -0.747 64.205 1.00 71.48 ? 504 THR A CB 1 ATOM 3827 O OG1 . THR A 1 503 ? -50.780 0.319 63.243 1.00 71.77 ? 504 THR A OG1 1 ATOM 3828 C CG2 . THR A 1 503 ? -50.081 -0.281 65.477 1.00 60.93 ? 504 THR A CG2 1 ATOM 3829 N N . ALA A 1 504 ? -51.936 -3.129 62.574 1.00 73.01 ? 505 ALA A N 1 ATOM 3830 C CA . ALA A 1 504 ? -52.631 -3.726 61.430 1.00 75.25 ? 505 ALA A CA 1 ATOM 3831 C C . ALA A 1 504 ? -53.271 -2.668 60.525 1.00 82.20 ? 505 ALA A C 1 ATOM 3832 O O . ALA A 1 504 ? -53.391 -2.859 59.308 1.00 79.84 ? 505 ALA A O 1 ATOM 3833 C CB . ALA A 1 504 ? -53.665 -4.742 61.888 1.00 74.02 ? 505 ALA A CB 1 ATOM 3834 N N . GLY A 1 505 ? -53.667 -1.547 61.125 1.00 86.55 ? 506 GLY A N 1 ATOM 3835 C CA . GLY A 1 505 ? -54.238 -0.443 60.374 1.00 77.43 ? 506 GLY A CA 1 ATOM 3836 C C . GLY A 1 505 ? -53.190 0.324 59.590 1.00 78.36 ? 506 GLY A C 1 ATOM 3837 O O . GLY A 1 505 ? -53.095 0.183 58.367 1.00 78.21 ? 506 GLY A O 1 ATOM 3838 N N . ALA A 1 506 ? -52.392 1.121 60.299 1.00 73.51 ? 507 ALA A N 1 ATOM 3839 C CA . ALA A 1 506 ? -51.408 1.995 59.667 1.00 65.08 ? 507 ALA A CA 1 ATOM 3840 C C . ALA A 1 506 ? -50.249 1.250 58.994 1.00 67.35 ? 507 ALA A C 1 ATOM 3841 O O . ALA A 1 506 ? -49.671 1.750 58.031 1.00 69.84 ? 507 ALA A O 1 ATOM 3842 C CB . ALA A 1 506 ? -50.887 3.018 60.666 1.00 67.11 ? 507 ALA A CB 1 ATOM 3843 N N . GLN A 1 507 ? -49.908 0.069 59.506 1.00 68.03 ? 508 GLN A N 1 ATOM 3844 C CA . GLN A 1 507 ? -48.900 -0.805 58.885 1.00 68.15 ? 508 GLN A CA 1 ATOM 3845 C C . GLN A 1 507 ? -47.551 -0.140 58.614 1.00 65.30 ? 508 GLN A C 1 ATOM 3846 O O . GLN A 1 507 ? -46.960 -0.329 57.549 1.00 62.52 ? 508 GLN A O 1 ATOM 3847 C CB . GLN A 1 507 ? -49.426 -1.398 57.577 1.00 67.33 ? 508 GLN A CB 1 ATOM 3848 C CG . GLN A 1 507 ? -50.672 -2.258 57.699 1.00 71.56 ? 508 GLN A CG 1 ATOM 3849 C CD . GLN A 1 507 ? -51.189 -2.703 56.336 1.00 79.74 ? 508 GLN A CD 1 ATOM 3850 O OE1 . GLN A 1 507 ? -50.421 -3.186 55.489 1.00 72.90 ? 508 GLN A OE1 1 ATOM 3851 N NE2 . GLN A 1 507 ? -52.488 -2.522 56.109 1.00 72.03 ? 508 GLN A NE2 1 ATOM 3852 N N . GLN A 1 508 ? -47.055 0.623 59.578 1.00 66.26 ? 509 GLN A N 1 ATOM 3853 C CA . GLN A 1 508 ? -45.797 1.336 59.390 1.00 66.12 ? 509 GLN A CA 1 ATOM 3854 C C . GLN A 1 508 ? -44.573 0.469 59.623 1.00 63.60 ? 509 GLN A C 1 ATOM 3855 O O . GLN A 1 508 ? -44.542 -0.360 60.535 1.00 57.27 ? 509 GLN A O 1 ATOM 3856 C CB . GLN A 1 508 ? -45.741 2.567 60.284 1.00 62.11 ? 509 GLN A CB 1 ATOM 3857 C CG . GLN A 1 508 ? -46.712 3.636 59.864 1.00 66.36 ? 509 GLN A CG 1 ATOM 3858 C CD . GLN A 1 508 ? -46.762 4.777 60.843 1.00 69.15 ? 509 GLN A CD 1 ATOM 3859 O OE1 . GLN A 1 508 ? -47.190 4.613 61.985 1.00 66.00 ? 509 GLN A OE1 1 ATOM 3860 N NE2 . GLN A 1 508 ? -46.309 5.944 60.407 1.00 71.81 ? 509 GLN A NE2 1 ATOM 3861 N N . TYR A 1 509 ? -43.570 0.671 58.777 1.00 57.36 ? 510 TYR A N 1 ATOM 3862 C CA . TYR A 1 509 ? -42.293 -0.011 58.904 1.00 58.91 ? 510 TYR A CA 1 ATOM 3863 C C . TYR A 1 509 ? -41.175 0.952 58.509 1.00 59.95 ? 510 TYR A C 1 ATOM 3864 O O . TYR A 1 509 ? -41.439 2.102 58.190 1.00 62.40 ? 510 TYR A O 1 ATOM 3865 C CB . TYR A 1 509 ? -42.267 -1.283 58.043 1.00 59.99 ? 510 TYR A CB 1 ATOM 3866 C CG . TYR A 1 509 ? -42.304 -1.061 56.532 1.00 63.57 ? 510 TYR A CG 1 ATOM 3867 C CD1 . TYR A 1 509 ? -43.496 -0.774 55.873 1.00 63.70 ? 510 TYR A CD1 1 ATOM 3868 C CD2 . TYR A 1 509 ? -41.147 -1.172 55.764 1.00 62.61 ? 510 TYR A CD2 1 ATOM 3869 C CE1 . TYR A 1 509 ? -43.531 -0.581 54.505 1.00 58.97 ? 510 TYR A CE1 1 ATOM 3870 C CE2 . TYR A 1 509 ? -41.172 -0.976 54.393 1.00 62.70 ? 510 TYR A CE2 1 ATOM 3871 C CZ . TYR A 1 509 ? -42.367 -0.687 53.766 1.00 63.71 ? 510 TYR A CZ 1 ATOM 3872 O OH . TYR A 1 509 ? -42.389 -0.498 52.398 1.00 63.35 ? 510 TYR A OH 1 ATOM 3873 N N . VAL A 1 510 ? -39.930 0.493 58.541 1.00 61.59 ? 511 VAL A N 1 ATOM 3874 C CA . VAL A 1 510 ? -38.799 1.350 58.189 1.00 59.19 ? 511 VAL A CA 1 ATOM 3875 C C . VAL A 1 510 ? -37.880 0.668 57.193 1.00 60.44 ? 511 VAL A C 1 ATOM 3876 O O . VAL A 1 510 ? -37.726 -0.554 57.204 1.00 57.86 ? 511 VAL A O 1 ATOM 3877 C CB . VAL A 1 510 ? -37.947 1.758 59.426 1.00 60.36 ? 511 VAL A CB 1 ATOM 3878 C CG1 . VAL A 1 510 ? -38.775 2.557 60.433 1.00 62.69 ? 511 VAL A CG1 1 ATOM 3879 C CG2 . VAL A 1 510 ? -37.325 0.532 60.097 1.00 62.41 ? 511 VAL A CG2 1 ATOM 3880 N N . SER A 1 511 ? -37.275 1.458 56.314 1.00 65.66 ? 512 SER A N 1 ATOM 3881 C CA . SER A 1 511 ? -36.241 0.920 55.447 1.00 65.39 ? 512 SER A CA 1 ATOM 3882 C C . SER A 1 511 ? -34.877 1.080 56.122 1.00 67.23 ? 512 SER A C 1 ATOM 3883 O O . SER A 1 511 ? -34.565 2.107 56.738 1.00 61.98 ? 512 SER A O 1 ATOM 3884 C CB . SER A 1 511 ? -36.267 1.562 54.056 1.00 66.18 ? 512 SER A CB 1 ATOM 3885 O OG . SER A 1 511 ? -35.985 2.945 54.125 1.00 73.06 ? 512 SER A OG 1 ATOM 3886 N N . LEU A 1 512 ? -34.080 0.031 56.027 1.00 65.78 ? 513 LEU A N 1 ATOM 3887 C CA . LEU A 1 512 ? -32.745 0.048 56.565 1.00 63.22 ? 513 LEU A CA 1 ATOM 3888 C C . LEU A 1 512 ? -31.736 0.052 55.425 1.00 64.95 ? 513 LEU A C 1 ATOM 3889 O O . LEU A 1 512 ? -31.516 -0.972 54.786 1.00 66.25 ? 513 LEU A O 1 ATOM 3890 C CB . LEU A 1 512 ? -32.554 -1.167 57.466 1.00 61.46 ? 513 LEU A CB 1 ATOM 3891 C CG . LEU A 1 512 ? -33.437 -1.118 58.715 1.00 61.57 ? 513 LEU A CG 1 ATOM 3892 C CD1 . LEU A 1 512 ? -33.256 -2.366 59.547 1.00 51.99 ? 513 LEU A CD1 1 ATOM 3893 C CD2 . LEU A 1 512 ? -33.126 0.132 59.529 1.00 55.87 ? 513 LEU A CD2 1 ATOM 3894 N N . ASP A 1 513 ? -31.158 1.220 55.150 1.00 68.08 ? 514 ASP A N 1 ATOM 3895 C CA . ASP A 1 513 ? -30.049 1.345 54.191 1.00 77.04 ? 514 ASP A CA 1 ATOM 3896 C C . ASP A 1 513 ? -29.085 2.444 54.644 1.00 71.64 ? 514 ASP A C 1 ATOM 3897 O O . ASP A 1 513 ? -29.137 2.866 55.796 1.00 69.15 ? 514 ASP A O 1 ATOM 3898 C CB . ASP A 1 513 ? -30.525 1.555 52.732 1.00 64.82 ? 514 ASP A CB 1 ATOM 3899 C CG . ASP A 1 513 ? -31.578 2.659 52.592 1.00 78.34 ? 514 ASP A CG 1 ATOM 3900 O OD1 . ASP A 1 513 ? -31.765 3.464 53.544 1.00 74.06 ? 514 ASP A OD1 1 ATOM 3901 O OD2 . ASP A 1 513 ? -32.219 2.720 51.512 1.00 75.27 ? 514 ASP A OD2 1 ATOM 3902 N N . LEU A 1 514 ? -28.207 2.891 53.752 1.00 73.98 ? 515 LEU A N 1 ATOM 3903 C CA . LEU A 1 514 ? -27.207 3.890 54.112 1.00 67.45 ? 515 LEU A CA 1 ATOM 3904 C C . LEU A 1 514 ? -27.862 5.238 54.414 1.00 72.49 ? 515 LEU A C 1 ATOM 3905 O O . LEU A 1 514 ? -27.375 6.001 55.246 1.00 76.50 ? 515 LEU A O 1 ATOM 3906 C CB . LEU A 1 514 ? -26.151 4.020 53.013 1.00 71.92 ? 515 LEU A CB 1 ATOM 3907 C CG . LEU A 1 514 ? -25.417 2.732 52.618 1.00 73.24 ? 515 LEU A CG 1 ATOM 3908 C CD1 . LEU A 1 514 ? -24.324 2.997 51.601 1.00 67.78 ? 515 LEU A CD1 1 ATOM 3909 C CD2 . LEU A 1 514 ? -24.836 2.044 53.828 1.00 67.77 ? 515 LEU A CD2 1 ATOM 3910 N N . ARG A 1 515 ? -28.978 5.524 53.753 1.00 69.49 ? 516 ARG A N 1 ATOM 3911 C CA . ARG A 1 515 ? -29.755 6.723 54.058 1.00 73.03 ? 516 ARG A CA 1 ATOM 3912 C C . ARG A 1 515 ? -30.420 6.557 55.416 1.00 72.32 ? 516 ARG A C 1 ATOM 3913 O O . ARG A 1 515 ? -30.535 5.439 55.909 1.00 81.11 ? 516 ARG A O 1 ATOM 3914 C CB . ARG A 1 515 ? -30.809 6.971 52.974 1.00 84.37 ? 516 ARG A CB 1 ATOM 3915 C CG . ARG A 1 515 ? -30.234 7.266 51.604 1.00 83.86 ? 516 ARG A CG 1 ATOM 3916 C CD . ARG A 1 515 ? -31.316 7.722 50.654 1.00 104.74 ? 516 ARG A CD 1 ATOM 3917 N NE . ARG A 1 515 ? -30.845 7.758 49.273 1.00 118.34 ? 516 ARG A NE 1 ATOM 3918 C CZ . ARG A 1 515 ? -31.584 8.161 48.245 1.00 126.38 ? 516 ARG A CZ 1 ATOM 3919 N NH1 . ARG A 1 515 ? -32.831 8.568 48.447 1.00 126.22 ? 516 ARG A NH1 1 ATOM 3920 N NH2 . ARG A 1 515 ? -31.078 8.159 47.016 1.00 128.16 ? 516 ARG A NH2 1 ATOM 3921 N N . PRO A 1 516 ? -30.856 7.663 56.041 1.00 79.66 ? 517 PRO A N 1 ATOM 3922 C CA . PRO A 1 516 ? -31.470 7.550 57.379 1.00 73.61 ? 517 PRO A CA 1 ATOM 3923 C C . PRO A 1 516 ? -32.828 6.843 57.373 1.00 73.26 ? 517 PRO A C 1 ATOM 3924 O O . PRO A 1 516 ? -33.388 6.576 56.307 1.00 77.98 ? 517 PRO A O 1 ATOM 3925 C CB . PRO A 1 516 ? -31.654 9.010 57.816 1.00 66.49 ? 517 PRO A CB 1 ATOM 3926 C CG . PRO A 1 516 ? -30.695 9.786 56.978 1.00 72.58 ? 517 PRO A CG 1 ATOM 3927 C CD . PRO A 1 516 ? -30.635 9.066 55.652 1.00 71.17 ? 517 PRO A CD 1 ATOM 3928 N N . LEU A 1 517 ? -33.343 6.546 58.563 1.00 78.90 ? 518 LEU A N 1 ATOM 3929 C CA . LEU A 1 517 ? -34.650 5.914 58.699 1.00 77.01 ? 518 LEU A CA 1 ATOM 3930 C C . LEU A 1 517 ? -35.710 6.620 57.865 1.00 71.79 ? 518 LEU A C 1 ATOM 3931 O O . LEU A 1 517 ? -35.898 7.831 57.972 1.00 72.80 ? 518 LEU A O 1 ATOM 3932 C CB . LEU A 1 517 ? -35.096 5.883 60.168 1.00 67.85 ? 518 LEU A CB 1 ATOM 3933 C CG . LEU A 1 517 ? -34.437 4.840 61.067 1.00 72.74 ? 518 LEU A CG 1 ATOM 3934 C CD1 . LEU A 1 517 ? -35.189 4.721 62.386 1.00 71.02 ? 518 LEU A CD1 1 ATOM 3935 C CD2 . LEU A 1 517 ? -34.335 3.491 60.376 1.00 66.08 ? 518 LEU A CD2 1 ATOM 3936 N N . GLU A 1 518 ? -36.394 5.848 57.031 1.00 69.31 ? 519 GLU A N 1 ATOM 3937 C CA . GLU A 1 518 ? -37.528 6.342 56.258 1.00 72.17 ? 519 GLU A CA 1 ATOM 3938 C C . GLU A 1 518 ? -38.730 5.507 56.696 1.00 64.52 ? 519 GLU A C 1 ATOM 3939 O O . GLU A 1 518 ? -38.623 4.291 56.802 1.00 65.75 ? 519 GLU A O 1 ATOM 3940 C CB . GLU A 1 518 ? -37.237 6.169 54.754 1.00 78.72 ? 519 GLU A CB 1 ATOM 3941 C CG . GLU A 1 518 ? -38.206 6.855 53.774 1.00 78.81 ? 519 GLU A CG 1 ATOM 3942 C CD . GLU A 1 518 ? -38.077 6.320 52.334 1.00 93.51 ? 519 GLU A CD 1 ATOM 3943 O OE1 . GLU A 1 518 ? -36.932 6.072 51.874 1.00 94.81 ? 519 GLU A OE1 1 ATOM 3944 O OE2 . GLU A 1 518 ? -39.125 6.136 51.665 1.00 85.93 ? 519 GLU A OE2 1 ATOM 3945 N N . VAL A 1 519 ? -39.861 6.145 56.982 1.00 68.47 ? 520 VAL A N 1 ATOM 3946 C CA . VAL A 1 519 ? -41.061 5.407 57.387 1.00 63.86 ? 520 VAL A CA 1 ATOM 3947 C C . VAL A 1 519 ? -42.022 5.215 56.212 1.00 72.41 ? 520 VAL A C 1 ATOM 3948 O O . VAL A 1 519 ? -42.420 6.181 55.565 1.00 73.15 ? 520 VAL A O 1 ATOM 3949 C CB . VAL A 1 519 ? -41.822 6.109 58.530 1.00 58.97 ? 520 VAL A CB 1 ATOM 3950 C CG1 . VAL A 1 519 ? -43.021 5.262 58.992 1.00 59.04 ? 520 VAL A CG1 1 ATOM 3951 C CG2 . VAL A 1 519 ? -40.893 6.393 59.687 1.00 60.28 ? 520 VAL A CG2 1 ATOM 3952 N N . ARG A 1 520 ? -42.396 3.965 55.946 1.00 68.13 ? 521 ARG A N 1 ATOM 3953 C CA . ARG A 1 520 ? -43.315 3.665 54.862 1.00 65.19 ? 521 ARG A CA 1 ATOM 3954 C C . ARG A 1 520 ? -44.554 2.974 55.395 1.00 64.78 ? 521 ARG A C 1 ATOM 3955 O O . ARG A 1 520 ? -44.672 2.739 56.594 1.00 64.03 ? 521 ARG A O 1 ATOM 3956 C CB . ARG A 1 520 ? -42.635 2.796 53.813 1.00 62.85 ? 521 ARG A CB 1 ATOM 3957 C CG . ARG A 1 520 ? -41.377 3.408 53.264 1.00 66.00 ? 521 ARG A CG 1 ATOM 3958 C CD . ARG A 1 520 ? -40.831 2.599 52.126 1.00 70.98 ? 521 ARG A CD 1 ATOM 3959 N NE . ARG A 1 520 ? -39.488 3.044 51.783 1.00 87.88 ? 521 ARG A NE 1 ATOM 3960 C CZ . ARG A 1 520 ? -38.652 2.367 51.002 1.00 89.89 ? 521 ARG A CZ 1 ATOM 3961 N NH1 . ARG A 1 520 ? -39.029 1.202 50.480 1.00 85.41 ? 521 ARG A NH1 1 ATOM 3962 N NH2 . ARG A 1 520 ? -37.440 2.856 50.749 1.00 85.16 ? 521 ARG A NH2 1 ATOM 3963 N N . ARG A 1 521 ? -45.482 2.658 54.500 1.00 62.91 ? 522 ARG A N 1 ATOM 3964 C CA . ARG A 1 521 ? -46.688 1.950 54.891 1.00 65.39 ? 522 ARG A CA 1 ATOM 3965 C C . ARG A 1 521 ? -46.942 0.720 54.018 1.00 66.14 ? 522 ARG A C 1 ATOM 3966 O O . ARG A 1 521 ? -46.654 0.712 52.818 1.00 68.91 ? 522 ARG A O 1 ATOM 3967 C CB . ARG A 1 521 ? -47.902 2.881 54.869 1.00 65.26 ? 522 ARG A CB 1 ATOM 3968 C CG . ARG A 1 521 ? -47.839 4.044 55.840 1.00 68.56 ? 522 ARG A CG 1 ATOM 3969 C CD . ARG A 1 521 ? -49.212 4.704 55.986 1.00 75.46 ? 522 ARG A CD 1 ATOM 3970 N NE . ARG A 1 521 ? -50.238 3.753 56.429 1.00 83.83 ? 522 ARG A NE 1 ATOM 3971 C CZ . ARG A 1 521 ? -51.221 3.271 55.662 1.00 87.71 ? 522 ARG A CZ 1 ATOM 3972 N NH1 . ARG A 1 521 ? -51.334 3.657 54.394 1.00 84.84 ? 522 ARG A NH1 1 ATOM 3973 N NH2 . ARG A 1 521 ? -52.103 2.404 56.164 1.00 78.35 ? 522 ARG A NH2 1 ATOM 3974 N N . GLY A 1 522 ? -47.482 -0.317 54.648 1.00 69.01 ? 523 GLY A N 1 ATOM 3975 C CA . GLY A 1 522 ? -47.870 -1.530 53.965 1.00 60.30 ? 523 GLY A CA 1 ATOM 3976 C C . GLY A 1 522 ? -46.690 -2.378 53.564 1.00 60.64 ? 523 GLY A C 1 ATOM 3977 O O . GLY A 1 522 ? -45.905 -2.004 52.696 1.00 70.60 ? 523 GLY A O 1 ATOM 3978 N N . LEU A 1 523 ? -46.558 -3.525 54.209 1.00 65.86 ? 524 LEU A N 1 ATOM 3979 C CA . LEU A 1 523 ? -45.567 -4.495 53.791 1.00 61.08 ? 524 LEU A CA 1 ATOM 3980 C C . LEU A 1 523 ? -46.160 -5.272 52.646 1.00 61.14 ? 524 LEU A C 1 ATOM 3981 O O . LEU A 1 523 ? -46.766 -6.331 52.855 1.00 69.28 ? 524 LEU A O 1 ATOM 3982 C CB . LEU A 1 523 ? -45.242 -5.453 54.928 1.00 59.44 ? 524 LEU A CB 1 ATOM 3983 C CG . LEU A 1 523 ? -44.325 -4.887 56.000 1.00 63.50 ? 524 LEU A CG 1 ATOM 3984 C CD1 . LEU A 1 523 ? -44.527 -5.661 57.297 1.00 70.34 ? 524 LEU A CD1 1 ATOM 3985 C CD2 . LEU A 1 523 ? -42.878 -4.963 55.527 1.00 60.31 ? 524 LEU A CD2 1 ATOM 3986 N N . ARG A 1 524 ? -46.019 -4.723 51.444 1.00 67.54 ? 525 ARG A N 1 ATOM 3987 C CA . ARG A 1 524 ? -46.443 -5.419 50.247 1.00 62.30 ? 525 ARG A CA 1 ATOM 3988 C C . ARG A 1 524 ? -47.942 -5.692 50.378 1.00 53.85 ? 525 ARG A C 1 ATOM 3989 O O . ARG A 1 524 ? -48.407 -6.815 50.176 1.00 54.08 ? 525 ARG A O 1 ATOM 3990 C CB . ARG A 1 524 ? -45.657 -6.722 50.149 1.00 60.68 ? 525 ARG A CB 1 ATOM 3991 C CG . ARG A 1 524 ? -45.303 -7.150 48.773 1.00 54.71 ? 525 ARG A CG 1 ATOM 3992 C CD . ARG A 1 524 ? -43.903 -6.757 48.363 1.00 50.47 ? 525 ARG A CD 1 ATOM 3993 N NE . ARG A 1 524 ? -43.639 -7.329 47.035 1.00 82.54 ? 525 ARG A NE 1 ATOM 3994 C CZ . ARG A 1 524 ? -44.226 -6.935 45.895 1.00 72.43 ? 525 ARG A CZ 1 ATOM 3995 N NH1 . ARG A 1 524 ? -45.105 -5.940 45.877 1.00 68.20 ? 525 ARG A NH1 1 ATOM 3996 N NH2 . ARG A 1 524 ? -43.921 -7.535 44.757 1.00 76.34 ? 525 ARG A NH2 1 ATOM 3997 N N . ALA A 1 525 ? -48.692 -4.652 50.726 1.00 52.64 ? 526 ALA A N 1 ATOM 3998 C CA . ALA A 1 525 ? -50.069 -4.823 51.177 1.00 53.94 ? 526 ALA A CA 1 ATOM 3999 C C . ALA A 1 525 ? -50.988 -5.467 50.146 1.00 60.25 ? 526 ALA A C 1 ATOM 4000 O O . ALA A 1 525 ? -51.718 -6.403 50.490 1.00 59.82 ? 526 ALA A O 1 ATOM 4001 C CB . ALA A 1 525 ? -50.644 -3.514 51.666 1.00 53.93 ? 526 ALA A CB 1 ATOM 4002 N N . GLN A 1 526 ? -50.943 -4.975 48.897 1.00 62.76 ? 527 GLN A N 1 ATOM 4003 C CA . GLN A 1 526 ? -51.783 -5.500 47.806 1.00 54.31 ? 527 GLN A CA 1 ATOM 4004 C C . GLN A 1 526 ? -51.554 -6.997 47.550 1.00 47.25 ? 527 GLN A C 1 ATOM 4005 O O . GLN A 1 526 ? -52.504 -7.777 47.483 1.00 52.23 ? 527 GLN A O 1 ATOM 4006 C CB . GLN A 1 526 ? -51.627 -4.686 46.493 1.00 57.49 ? 527 GLN A CB 1 ATOM 4007 C CG . GLN A 1 526 ? -51.909 -3.159 46.563 1.00 49.20 ? 527 GLN A CG 1 ATOM 4008 C CD . GLN A 1 526 ? -53.156 -2.776 47.374 1.00 61.61 ? 527 GLN A CD 1 ATOM 4009 O OE1 . GLN A 1 526 ? -54.186 -3.448 47.321 1.00 66.82 ? 527 GLN A OE1 1 ATOM 4010 N NE2 . GLN A 1 526 ? -53.060 -1.681 48.122 1.00 57.87 ? 527 GLN A NE2 1 ATOM 4011 N N . ALA A 1 527 ? -50.297 -7.401 47.411 1.00 45.70 ? 528 ALA A N 1 ATOM 4012 C CA . ALA A 1 527 ? -49.962 -8.822 47.272 1.00 48.23 ? 528 ALA A CA 1 ATOM 4013 C C . ALA A 1 527 ? -50.470 -9.690 48.438 1.00 54.89 ? 528 ALA A C 1 ATOM 4014 O O . ALA A 1 527 ? -51.012 -10.790 48.246 1.00 50.95 ? 528 ALA A O 1 ATOM 4015 C CB . ALA A 1 527 ? -48.464 -8.993 47.126 1.00 50.93 ? 528 ALA A CB 1 ATOM 4016 N N . CYS A 1 528 ? -50.285 -9.200 49.658 1.00 53.93 ? 529 CYS A N 1 ATOM 4017 C CA . CYS A 1 528 ? -50.619 -10.010 50.819 1.00 57.06 ? 529 CYS A CA 1 ATOM 4018 C C . CYS A 1 528 ? -52.110 -10.313 50.912 1.00 49.48 ? 529 CYS A C 1 ATOM 4019 O O . CYS A 1 528 ? -52.488 -11.393 51.364 1.00 51.03 ? 529 CYS A O 1 ATOM 4020 C CB . CYS A 1 528 ? -50.008 -9.430 52.112 1.00 62.59 ? 529 CYS A CB 1 ATOM 4021 S SG . CYS A 1 528 ? -48.205 -9.703 52.089 1.00 90.24 ? 529 CYS A SG 1 ATOM 4022 N N . ALA A 1 529 ? -52.947 -9.399 50.430 1.00 46.92 ? 530 ALA A N 1 ATOM 4023 C CA . ALA A 1 529 ? -54.384 -9.662 50.376 1.00 47.20 ? 530 ALA A CA 1 ATOM 4024 C C . ALA A 1 529 ? -54.697 -10.824 49.435 1.00 56.20 ? 530 ALA A C 1 ATOM 4025 O O . ALA A 1 529 ? -55.628 -11.600 49.673 1.00 54.52 ? 530 ALA A O 1 ATOM 4026 C CB . ALA A 1 529 ? -55.131 -8.426 49.968 1.00 45.97 ? 530 ALA A CB 1 ATOM 4027 N N . PHE A 1 530 ? -53.910 -10.947 48.369 1.00 49.76 ? 531 PHE A N 1 ATOM 4028 C CA . PHE A 1 530 ? -54.111 -12.042 47.444 1.00 53.25 ? 531 PHE A CA 1 ATOM 4029 C C . PHE A 1 530 ? -53.754 -13.367 48.093 1.00 54.95 ? 531 PHE A C 1 ATOM 4030 O O . PHE A 1 530 ? -54.510 -14.340 47.999 1.00 52.84 ? 531 PHE A O 1 ATOM 4031 C CB . PHE A 1 530 ? -53.297 -11.846 46.161 1.00 52.74 ? 531 PHE A CB 1 ATOM 4032 C CG . PHE A 1 530 ? -53.130 -13.099 45.367 1.00 52.04 ? 531 PHE A CG 1 ATOM 4033 C CD1 . PHE A 1 530 ? -54.216 -13.663 44.700 1.00 60.98 ? 531 PHE A CD1 1 ATOM 4034 C CD2 . PHE A 1 530 ? -51.898 -13.726 45.290 1.00 51.56 ? 531 PHE A CD2 1 ATOM 4035 C CE1 . PHE A 1 530 ? -54.075 -14.833 43.968 1.00 61.30 ? 531 PHE A CE1 1 ATOM 4036 C CE2 . PHE A 1 530 ? -51.747 -14.902 44.563 1.00 55.70 ? 531 PHE A CE2 1 ATOM 4037 C CZ . PHE A 1 530 ? -52.837 -15.451 43.895 1.00 62.40 ? 531 PHE A CZ 1 ATOM 4038 N N . TRP A 1 531 ? -52.596 -13.403 48.746 1.00 54.02 ? 532 TRP A N 1 ATOM 4039 C CA . TRP A 1 531 ? -52.111 -14.648 49.362 1.00 60.32 ? 532 TRP A CA 1 ATOM 4040 C C . TRP A 1 531 ? -52.855 -15.048 50.626 1.00 53.89 ? 532 TRP A C 1 ATOM 4041 O O . TRP A 1 531 ? -53.147 -16.227 50.814 1.00 61.31 ? 532 TRP A O 1 ATOM 4042 C CB . TRP A 1 531 ? -50.611 -14.590 49.657 1.00 50.89 ? 532 TRP A CB 1 ATOM 4043 C CG . TRP A 1 531 ? -49.756 -14.560 48.417 1.00 52.37 ? 532 TRP A CG 1 ATOM 4044 C CD1 . TRP A 1 531 ? -49.079 -13.485 47.909 1.00 45.27 ? 532 TRP A CD1 1 ATOM 4045 C CD2 . TRP A 1 531 ? -49.489 -15.660 47.528 1.00 48.97 ? 532 TRP A CD2 1 ATOM 4046 N NE1 . TRP A 1 531 ? -48.390 -13.856 46.775 1.00 52.34 ? 532 TRP A NE1 1 ATOM 4047 C CE2 . TRP A 1 531 ? -48.634 -15.180 46.514 1.00 48.10 ? 532 TRP A CE2 1 ATOM 4048 C CE3 . TRP A 1 531 ? -49.892 -17.002 47.494 1.00 43.62 ? 532 TRP A CE3 1 ATOM 4049 C CZ2 . TRP A 1 531 ? -48.175 -15.993 45.478 1.00 51.61 ? 532 TRP A CZ2 1 ATOM 4050 C CZ3 . TRP A 1 531 ? -49.435 -17.810 46.471 1.00 49.23 ? 532 TRP A CZ3 1 ATOM 4051 C CH2 . TRP A 1 531 ? -48.584 -17.304 45.472 1.00 52.32 ? 532 TRP A CH2 1 ATOM 4052 N N . ASN A 1 532 ? -53.168 -14.071 51.474 1.00 54.91 ? 533 ASN A N 1 ATOM 4053 C CA . ASN A 1 532 ? -53.784 -14.339 52.782 1.00 55.98 ? 533 ASN A CA 1 ATOM 4054 C C . ASN A 1 532 ? -55.319 -14.316 52.812 1.00 57.28 ? 533 ASN A C 1 ATOM 4055 O O . ASN A 1 532 ? -55.932 -15.018 53.606 1.00 58.93 ? 533 ASN A O 1 ATOM 4056 C CB . ASN A 1 532 ? -53.244 -13.388 53.865 1.00 50.34 ? 533 ASN A CB 1 ATOM 4057 C CG . ASN A 1 532 ? -51.729 -13.450 54.020 1.00 58.64 ? 533 ASN A CG 1 ATOM 4058 O OD1 . ASN A 1 532 ? -51.106 -14.522 53.926 1.00 51.81 ? 533 ASN A OD1 1 ATOM 4059 N ND2 . ASN A 1 532 ? -51.122 -12.283 54.264 1.00 59.80 ? 533 ASN A ND2 1 ATOM 4060 N N . ARG A 1 533 ? -55.951 -13.522 51.959 1.00 60.87 ? 534 ARG A N 1 ATOM 4061 C CA . ARG A 1 533 ? -57.415 -13.460 51.971 1.00 61.64 ? 534 ARG A CA 1 ATOM 4062 C C . ARG A 1 533 ? -58.114 -14.157 50.808 1.00 61.55 ? 534 ARG A C 1 ATOM 4063 O O . ARG A 1 533 ? -59.053 -14.924 51.027 1.00 62.06 ? 534 ARG A O 1 ATOM 4064 C CB . ARG A 1 533 ? -57.893 -12.023 52.062 1.00 53.00 ? 534 ARG A CB 1 ATOM 4065 C CG . ARG A 1 533 ? -57.119 -11.230 53.051 1.00 48.97 ? 534 ARG A CG 1 ATOM 4066 C CD . ARG A 1 533 ? -57.461 -9.778 52.914 1.00 57.03 ? 534 ARG A CD 1 ATOM 4067 N NE . ARG A 1 533 ? -57.728 -9.149 54.199 1.00 75.39 ? 534 ARG A NE 1 ATOM 4068 C CZ . ARG A 1 533 ? -58.892 -9.221 54.837 1.00 73.93 ? 534 ARG A CZ 1 ATOM 4069 N NH1 . ARG A 1 533 ? -59.917 -9.910 54.319 1.00 63.98 ? 534 ARG A NH1 1 ATOM 4070 N NH2 . ARG A 1 533 ? -59.025 -8.599 56.000 1.00 70.38 ? 534 ARG A NH2 1 ATOM 4071 N N . PHE A 1 534 ? -57.677 -13.890 49.578 1.00 64.19 ? 535 PHE A N 1 ATOM 4072 C CA . PHE A 1 534 ? -58.371 -14.453 48.414 1.00 59.07 ? 535 PHE A CA 1 ATOM 4073 C C . PHE A 1 534 ? -57.999 -15.901 48.083 1.00 62.34 ? 535 PHE A C 1 ATOM 4074 O O . PHE A 1 534 ? -58.880 -16.755 48.029 1.00 68.86 ? 535 PHE A O 1 ATOM 4075 C CB . PHE A 1 534 ? -58.237 -13.554 47.182 1.00 64.19 ? 535 PHE A CB 1 ATOM 4076 C CG . PHE A 1 534 ? -58.772 -14.175 45.916 1.00 58.91 ? 535 PHE A CG 1 ATOM 4077 C CD1 . PHE A 1 534 ? -60.142 -14.286 45.704 1.00 57.39 ? 535 PHE A CD1 1 ATOM 4078 C CD2 . PHE A 1 534 ? -57.905 -14.654 44.943 1.00 57.12 ? 535 PHE A CD2 1 ATOM 4079 C CE1 . PHE A 1 534 ? -60.637 -14.860 44.539 1.00 65.14 ? 535 PHE A CE1 1 ATOM 4080 C CE2 . PHE A 1 534 ? -58.400 -15.230 43.767 1.00 65.36 ? 535 PHE A CE2 1 ATOM 4081 C CZ . PHE A 1 534 ? -59.763 -15.332 43.566 1.00 58.01 ? 535 PHE A CZ 1 ATOM 4082 N N . LEU A 1 535 ? -56.713 -16.177 47.862 1.00 55.62 ? 536 LEU A N 1 ATOM 4083 C CA . LEU A 1 535 ? -56.257 -17.544 47.559 1.00 59.25 ? 536 LEU A CA 1 ATOM 4084 C C . LEU A 1 535 ? -56.856 -18.669 48.432 1.00 74.70 ? 536 LEU A C 1 ATOM 4085 O O . LEU A 1 535 ? -57.256 -19.707 47.892 1.00 73.68 ? 536 LEU A O 1 ATOM 4086 C CB . LEU A 1 535 ? -54.723 -17.645 47.549 1.00 59.15 ? 536 LEU A CB 1 ATOM 4087 C CG . LEU A 1 535 ? -54.212 -18.924 46.875 1.00 63.91 ? 536 LEU A CG 1 ATOM 4088 C CD1 . LEU A 1 535 ? -54.819 -19.017 45.468 1.00 72.56 ? 536 LEU A CD1 1 ATOM 4089 C CD2 . LEU A 1 535 ? -52.692 -18.991 46.799 1.00 51.45 ? 536 LEU A CD2 1 ATOM 4090 N N . PRO A 1 536 ? -56.918 -18.474 49.776 1.00 67.47 ? 537 PRO A N 1 ATOM 4091 C CA . PRO A 1 536 ? -57.586 -19.489 50.597 1.00 68.70 ? 537 PRO A CA 1 ATOM 4092 C C . PRO A 1 536 ? -59.059 -19.710 50.225 1.00 74.55 ? 537 PRO A C 1 ATOM 4093 O O . PRO A 1 536 ? -59.501 -20.860 50.214 1.00 77.13 ? 537 PRO A O 1 ATOM 4094 C CB . PRO A 1 536 ? -57.467 -18.918 52.019 1.00 64.43 ? 537 PRO A CB 1 ATOM 4095 C CG . PRO A 1 536 ? -56.271 -18.056 51.973 1.00 59.12 ? 537 PRO A CG 1 ATOM 4096 C CD . PRO A 1 536 ? -56.324 -17.419 50.621 1.00 62.03 ? 537 PRO A CD 1 ATOM 4097 N N . LYS A 1 537 ? -59.795 -18.637 49.931 1.00 75.58 ? 538 LYS A N 1 ATOM 4098 C CA . LYS A 1 537 ? -61.189 -18.748 49.482 1.00 72.50 ? 538 LYS A CA 1 ATOM 4099 C C . LYS A 1 537 ? -61.303 -19.508 48.161 1.00 75.69 ? 538 LYS A C 1 ATOM 4100 O O . LYS A 1 537 ? -62.268 -20.240 47.939 1.00 80.55 ? 538 LYS A O 1 ATOM 4101 C CB . LYS A 1 537 ? -61.842 -17.365 49.362 1.00 62.06 ? 538 LYS A CB 1 ATOM 4102 C CG . LYS A 1 537 ? -62.078 -16.699 50.704 1.00 67.62 ? 538 LYS A CG 1 ATOM 4103 C CD . LYS A 1 537 ? -62.467 -15.229 50.606 1.00 67.30 ? 538 LYS A CD 1 ATOM 4104 C CE . LYS A 1 537 ? -62.458 -14.603 51.996 1.00 69.12 ? 538 LYS A CE 1 ATOM 4105 N NZ . LYS A 1 537 ? -62.689 -13.136 52.002 1.00 69.91 ? 538 LYS A NZ 1 ATOM 4106 N N . LEU A 1 538 ? -60.312 -19.341 47.292 1.00 74.02 ? 539 LEU A N 1 ATOM 4107 C CA . LEU A 1 538 ? -60.327 -20.007 45.995 1.00 80.94 ? 539 LEU A CA 1 ATOM 4108 C C . LEU A 1 538 ? -60.094 -21.499 46.153 1.00 87.32 ? 539 LEU A C 1 ATOM 4109 O O . LEU A 1 538 ? -60.782 -22.314 45.544 1.00 95.31 ? 539 LEU A O 1 ATOM 4110 C CB . LEU A 1 538 ? -59.279 -19.408 45.049 1.00 73.60 ? 539 LEU A CB 1 ATOM 4111 C CG . LEU A 1 538 ? -59.196 -20.045 43.660 1.00 76.27 ? 539 LEU A CG 1 ATOM 4112 C CD1 . LEU A 1 538 ? -58.917 -18.987 42.618 1.00 69.80 ? 539 LEU A CD1 1 ATOM 4113 C CD2 . LEU A 1 538 ? -58.125 -21.118 43.614 1.00 77.58 ? 539 LEU A CD2 1 ATOM 4114 N N . LEU A 1 539 ? -59.104 -21.852 46.962 1.00 88.04 ? 540 LEU A N 1 ATOM 4115 C CA . LEU A 1 539 ? -58.734 -23.252 47.132 1.00 92.78 ? 540 LEU A CA 1 ATOM 4116 C C . LEU A 1 539 ? -59.789 -24.008 47.939 1.00 89.66 ? 540 LEU A C 1 ATOM 4117 O O . LEU A 1 539 ? -60.037 -25.192 47.706 1.00 94.19 ? 540 LEU A O 1 ATOM 4118 C CB . LEU A 1 539 ? -57.349 -23.364 47.773 1.00 88.17 ? 540 LEU A CB 1 ATOM 4119 C CG . LEU A 1 539 ? -56.194 -22.791 46.943 1.00 85.54 ? 540 LEU A CG 1 ATOM 4120 C CD1 . LEU A 1 539 ? -54.890 -22.914 47.710 1.00 79.27 ? 540 LEU A CD1 1 ATOM 4121 C CD2 . LEU A 1 539 ? -56.092 -23.460 45.555 1.00 82.72 ? 540 LEU A CD2 1 ATOM 4122 N N . SER A 1 540 ? -60.427 -23.303 48.867 1.00 87.52 ? 541 SER A N 1 ATOM 4123 C CA . SER A 1 540 ? -61.528 -23.853 49.653 1.00 81.77 ? 541 SER A CA 1 ATOM 4124 C C . SER A 1 540 ? -62.801 -24.086 48.836 1.00 93.43 ? 541 SER A C 1 ATOM 4125 O O . SER A 1 540 ? -63.819 -24.502 49.385 1.00 93.87 ? 541 SER A O 1 ATOM 4126 C CB . SER A 1 540 ? -61.852 -22.920 50.816 1.00 79.83 ? 541 SER A CB 1 ATOM 4127 O OG . SER A 1 540 ? -63.008 -23.355 51.508 1.00 96.23 ? 541 SER A OG 1 ATOM 4128 N N . ALA A 1 541 ? -62.750 -23.806 47.535 1.00 96.65 ? 542 ALA A N 1 ATOM 4129 C CA . ALA A 1 541 ? -63.930 -23.928 46.688 1.00 93.42 ? 542 ALA A CA 1 ATOM 4130 C C . ALA A 1 541 ? -63.654 -24.696 45.395 1.00 99.05 ? 542 ALA A C 1 ATOM 4131 O O . ALA A 1 541 ? -64.566 -25.272 44.810 1.00 103.49 ? 542 ALA A O 1 ATOM 4132 C CB . ALA A 1 541 ? -64.504 -22.553 46.383 1.00 91.12 ? 542 ALA A CB 1 ATOM 4133 N N . THR A 1 542 ? -62.401 -24.703 44.950 1.00 100.86 ? 543 THR A N 1 ATOM 4134 C CA . THR A 1 542 ? -62.035 -25.418 43.728 1.00 105.83 ? 543 THR A CA 1 ATOM 4135 C C . THR A 1 542 ? -61.056 -26.557 44.013 1.00 104.68 ? 543 THR A C 1 ATOM 4136 O O . THR A 1 542 ? -61.439 -27.590 44.566 1.00 103.41 ? 543 THR A O 1 ATOM 4137 C CB . THR A 1 542 ? -61.453 -24.471 42.628 1.00 107.94 ? 543 THR A CB 1 ATOM 4138 O OG1 . THR A 1 542 ? -60.146 -24.004 43.003 1.00 104.64 ? 543 THR A OG1 1 ATOM 4139 C CG2 . THR A 1 542 ? -62.378 -23.282 42.391 1.00 95.39 ? 543 THR A CG2 1 ATOM 4140 N N . THR B 2 1 ? -9.432 -36.476 31.761 1.00 93.90 ? 1 THR B N 1 ATOM 4141 C CA . THR B 2 1 ? -10.151 -35.234 32.015 1.00 93.35 ? 1 THR B CA 1 ATOM 4142 C C . THR B 2 1 ? -10.155 -34.881 33.509 1.00 96.56 ? 1 THR B C 1 ATOM 4143 O O . THR B 2 1 ? -10.200 -35.763 34.376 1.00 90.68 ? 1 THR B O 1 ATOM 4144 C CB . THR B 2 1 ? -11.608 -35.316 31.518 1.00 96.85 ? 1 THR B CB 1 ATOM 4145 O OG1 . THR B 2 1 ? -11.719 -36.313 30.492 1.00 92.13 ? 1 THR B OG1 1 ATOM 4146 C CG2 . THR B 2 1 ? -12.075 -33.958 30.990 1.00 89.65 ? 1 THR B CG2 1 ATOM 4147 N N . MET B 2 2 ? -10.109 -33.583 33.802 1.00 91.73 ? 2 MET B N 1 ATOM 4148 C CA . MET B 2 2 ? -10.156 -33.101 35.177 1.00 90.47 ? 2 MET B CA 1 ATOM 4149 C C . MET B 2 2 ? -11.570 -32.685 35.577 1.00 92.26 ? 2 MET B C 1 ATOM 4150 O O . MET B 2 2 ? -12.061 -31.640 35.146 1.00 88.43 ? 2 MET B O 1 ATOM 4151 C CB . MET B 2 2 ? -9.181 -31.937 35.380 1.00 87.92 ? 2 MET B CB 1 ATOM 4152 C CG . MET B 2 2 ? -7.714 -32.346 35.308 1.00 94.57 ? 2 MET B CG 1 ATOM 4153 S SD . MET B 2 2 ? -7.243 -33.656 36.467 1.00 89.30 ? 2 MET B SD 1 ATOM 4154 C CE . MET B 2 2 ? -7.396 -32.791 38.033 1.00 90.96 ? 2 MET B CE 1 ATOM 4155 N N . CYS B 2 3 ? -12.207 -33.503 36.417 1.00 89.93 ? 3 CYS B N 1 ATOM 4156 C CA . CYS B 2 3 ? -13.598 -33.278 36.803 1.00 83.10 ? 3 CYS B CA 1 ATOM 4157 C C . CYS B 2 3 ? -13.817 -33.136 38.301 1.00 80.21 ? 3 CYS B C 1 ATOM 4158 O O . CYS B 2 3 ? -12.987 -33.542 39.108 1.00 81.56 ? 3 CYS B O 1 ATOM 4159 C CB . CYS B 2 3 ? -14.488 -34.389 36.245 1.00 87.61 ? 3 CYS B CB 1 ATOM 4160 S SG . CYS B 2 3 ? -14.917 -34.136 34.482 1.00 99.81 ? 3 CYS B SG 1 ATOM 4161 N N . TYR B 2 4 ? -14.947 -32.547 38.669 1.00 76.98 ? 4 TYR B N 1 ATOM 4162 C CA . TYR B 2 4 ? -15.267 -32.372 40.073 1.00 68.96 ? 4 TYR B CA 1 ATOM 4163 C C . TYR B 2 4 ? -15.665 -33.693 40.734 1.00 72.81 ? 4 TYR B C 1 ATOM 4164 O O . TYR B 2 4 ? -16.137 -34.626 40.074 1.00 71.01 ? 4 TYR B O 1 ATOM 4165 C CB . TYR B 2 4 ? -16.382 -31.361 40.239 1.00 67.75 ? 4 TYR B CB 1 ATOM 4166 C CG . TYR B 2 4 ? -16.020 -29.942 39.885 1.00 71.60 ? 4 TYR B CG 1 ATOM 4167 C CD1 . TYR B 2 4 ? -15.161 -29.199 40.688 1.00 69.24 ? 4 TYR B CD1 1 ATOM 4168 C CD2 . TYR B 2 4 ? -16.580 -29.323 38.771 1.00 74.82 ? 4 TYR B CD2 1 ATOM 4169 C CE1 . TYR B 2 4 ? -14.850 -27.883 40.378 1.00 66.60 ? 4 TYR B CE1 1 ATOM 4170 C CE2 . TYR B 2 4 ? -16.281 -28.007 38.455 1.00 77.57 ? 4 TYR B CE2 1 ATOM 4171 C CZ . TYR B 2 4 ? -15.414 -27.292 39.261 1.00 80.42 ? 4 TYR B CZ 1 ATOM 4172 O OH . TYR B 2 4 ? -15.117 -25.983 38.939 1.00 89.41 ? 4 TYR B OH 1 ATOM 4173 N N . SER B 2 5 ? -15.471 -33.762 42.047 1.00 69.75 ? 5 SER B N 1 ATOM 4174 C CA . SER B 2 5 ? -15.743 -34.976 42.800 1.00 62.63 ? 5 SER B CA 1 ATOM 4175 C C . SER B 2 5 ? -16.222 -34.607 44.200 1.00 71.04 ? 5 SER B C 1 ATOM 4176 O O . SER B 2 5 ? -15.678 -33.684 44.820 1.00 66.40 ? 5 SER B O 1 ATOM 4177 C CB . SER B 2 5 ? -14.476 -35.825 42.888 1.00 65.97 ? 5 SER B CB 1 ATOM 4178 O OG . SER B 2 5 ? -14.787 -37.194 43.055 1.00 64.08 ? 5 SER B OG 1 ATOM 4179 N N . HIS B 2 6 ? -17.231 -35.343 44.678 1.00 70.78 ? 6 HIS B N 1 ATOM 4180 C CA . HIS B 2 6 ? -17.852 -35.144 45.990 1.00 60.86 ? 6 HIS B CA 1 ATOM 4181 C C . HIS B 2 6 ? -19.099 -36.006 46.182 1.00 62.52 ? 6 HIS B C 1 ATOM 4182 O O . HIS B 2 6 ? -19.728 -36.424 45.205 1.00 62.06 ? 6 HIS B O 1 ATOM 4183 C CB . HIS B 2 6 ? -18.248 -33.683 46.188 1.00 65.49 ? 6 HIS B CB 1 ATOM 4184 C CG . HIS B 2 6 ? -19.364 -33.228 45.301 1.00 61.76 ? 6 HIS B CG 1 ATOM 4185 N ND1 . HIS B 2 6 ? -20.667 -33.637 45.476 1.00 61.02 ? 6 HIS B ND1 1 ATOM 4186 C CD2 . HIS B 2 6 ? -19.375 -32.377 44.250 1.00 62.11 ? 6 HIS B CD2 1 ATOM 4187 C CE1 . HIS B 2 6 ? -21.431 -33.063 44.566 1.00 63.53 ? 6 HIS B CE1 1 ATOM 4188 N NE2 . HIS B 2 6 ? -20.672 -32.291 43.811 1.00 59.55 ? 6 HIS B NE2 1 ATOM 4189 N N . THR B 2 7 ? -19.471 -36.239 47.441 1.00 56.09 ? 7 THR B N 1 ATOM 4190 C CA . THR B 2 7 ? -20.722 -36.918 47.767 1.00 53.64 ? 7 THR B CA 1 ATOM 4191 C C . THR B 2 7 ? -21.796 -35.895 48.173 1.00 58.52 ? 7 THR B C 1 ATOM 4192 O O . THR B 2 7 ? -21.670 -34.699 47.893 1.00 57.78 ? 7 THR B O 1 ATOM 4193 C CB . THR B 2 7 ? -20.533 -37.920 48.922 1.00 57.67 ? 7 THR B CB 1 ATOM 4194 O OG1 . THR B 2 7 ? -20.414 -37.199 50.153 1.00 60.45 ? 7 THR B OG1 1 ATOM 4195 C CG2 . THR B 2 7 ? -19.283 -38.743 48.715 1.00 46.24 ? 7 THR B CG2 1 ATOM 4196 N N . THR B 2 8 ? -22.848 -36.368 48.834 1.00 58.27 ? 8 THR B N 1 ATOM 4197 C CA . THR B 2 8 ? -23.851 -35.480 49.417 1.00 61.21 ? 8 THR B CA 1 ATOM 4198 C C . THR B 2 8 ? -23.327 -34.731 50.659 1.00 64.85 ? 8 THR B C 1 ATOM 4199 O O . THR B 2 8 ? -23.871 -33.688 51.058 1.00 62.81 ? 8 THR B O 1 ATOM 4200 C CB . THR B 2 8 ? -25.099 -36.266 49.833 1.00 62.13 ? 8 THR B CB 1 ATOM 4201 O OG1 . THR B 2 8 ? -24.701 -37.394 50.618 1.00 62.80 ? 8 THR B OG1 1 ATOM 4202 C CG2 . THR B 2 8 ? -25.859 -36.753 48.623 1.00 55.26 ? 8 THR B CG2 1 ATOM 4203 N N . THR B 2 9 ? -22.273 -35.258 51.274 1.00 64.45 ? 9 THR B N 1 ATOM 4204 C CA . THR B 2 9 ? -21.788 -34.693 52.538 1.00 63.98 ? 9 THR B CA 1 ATOM 4205 C C . THR B 2 9 ? -20.317 -34.266 52.498 1.00 65.56 ? 9 THR B C 1 ATOM 4206 O O . THR B 2 9 ? -19.651 -34.227 53.514 1.00 61.44 ? 9 THR B O 1 ATOM 4207 C CB . THR B 2 9 ? -21.993 -35.671 53.718 1.00 61.01 ? 9 THR B CB 1 ATOM 4208 O OG1 . THR B 2 9 ? -21.282 -36.890 53.468 1.00 61.55 ? 9 THR B OG1 1 ATOM 4209 C CG2 . THR B 2 9 ? -23.484 -35.980 53.933 1.00 62.34 ? 9 THR B CG2 1 ATOM 4210 N N . SER B 2 10 ? -19.809 -33.941 51.322 1.00 66.94 ? 10 SER B N 1 ATOM 4211 C CA . SER B 2 10 ? -18.420 -33.518 51.222 1.00 66.37 ? 10 SER B CA 1 ATOM 4212 C C . SER B 2 10 ? -18.325 -32.359 50.237 1.00 69.97 ? 10 SER B C 1 ATOM 4213 O O . SER B 2 10 ? -19.161 -32.234 49.341 1.00 64.53 ? 10 SER B O 1 ATOM 4214 C CB . SER B 2 10 ? -17.531 -34.683 50.774 1.00 67.51 ? 10 SER B CB 1 ATOM 4215 O OG . SER B 2 10 ? -17.686 -34.963 49.383 1.00 64.51 ? 10 SER B OG 1 ATOM 4216 N N . ARG B 2 11 ? -17.326 -31.503 50.418 1.00 70.73 ? 11 ARG B N 1 ATOM 4217 C CA . ARG B 2 11 ? -17.109 -30.403 49.489 1.00 72.46 ? 11 ARG B CA 1 ATOM 4218 C C . ARG B 2 11 ? -16.544 -30.918 48.165 1.00 71.14 ? 11 ARG B C 1 ATOM 4219 O O . ARG B 2 11 ? -15.957 -32.011 48.092 1.00 63.88 ? 11 ARG B O 1 ATOM 4220 C CB . ARG B 2 11 ? -16.176 -29.348 50.085 1.00 78.64 ? 11 ARG B CB 1 ATOM 4221 C CG . ARG B 2 11 ? -16.860 -28.038 50.459 1.00 83.83 ? 11 ARG B CG 1 ATOM 4222 C CD . ARG B 2 11 ? -16.532 -27.692 51.903 1.00 97.21 ? 11 ARG B CD 1 ATOM 4223 N NE . ARG B 2 11 ? -16.857 -26.310 52.250 1.00 109.06 ? 11 ARG B NE 1 ATOM 4224 C CZ . ARG B 2 11 ? -16.550 -25.748 53.422 1.00 110.03 ? 11 ARG B CZ 1 ATOM 4225 N NH1 . ARG B 2 11 ? -15.910 -26.455 54.353 1.00 104.74 ? 11 ARG B NH1 1 ATOM 4226 N NH2 . ARG B 2 11 ? -16.877 -24.480 53.672 1.00 96.91 ? 11 ARG B NH2 1 ATOM 4227 N N . ALA B 2 12 ? -16.736 -30.106 47.130 1.00 65.00 ? 12 ALA B N 1 ATOM 4228 C CA . ALA B 2 12 ? -16.348 -30.437 45.767 1.00 71.11 ? 12 ALA B CA 1 ATOM 4229 C C . ALA B 2 12 ? -14.848 -30.259 45.535 1.00 69.85 ? 12 ALA B C 1 ATOM 4230 O O . ALA B 2 12 ? -14.327 -29.149 45.642 1.00 68.90 ? 12 ALA B O 1 ATOM 4231 C CB . ALA B 2 12 ? -17.154 -29.575 44.775 1.00 68.29 ? 12 ALA B CB 1 ATOM 4232 N N . ILE B 2 13 ? -14.162 -31.355 45.221 1.00 68.21 ? 13 ILE B N 1 ATOM 4233 C CA . ILE B 2 13 ? -12.741 -31.307 44.875 1.00 72.94 ? 13 ILE B CA 1 ATOM 4234 C C . ILE B 2 13 ? -12.498 -31.666 43.396 1.00 81.26 ? 13 ILE B C 1 ATOM 4235 O O . ILE B 2 13 ? -13.392 -32.191 42.722 1.00 79.46 ? 13 ILE B O 1 ATOM 4236 C CB . ILE B 2 13 ? -11.910 -32.233 45.780 1.00 71.22 ? 13 ILE B CB 1 ATOM 4237 C CG1 . ILE B 2 13 ? -12.275 -33.700 45.534 1.00 76.80 ? 13 ILE B CG1 1 ATOM 4238 C CG2 . ILE B 2 13 ? -12.111 -31.861 47.232 1.00 65.85 ? 13 ILE B CG2 1 ATOM 4239 C CD1 . ILE B 2 13 ? -11.669 -34.663 46.550 1.00 69.06 ? 13 ILE B CD1 1 ATOM 4240 N N . LEU B 2 14 ? -11.300 -31.365 42.891 1.00 83.02 ? 14 LEU B N 1 ATOM 4241 C CA . LEU B 2 14 ? -10.919 -31.748 41.526 1.00 80.61 ? 14 LEU B CA 1 ATOM 4242 C C . LEU B 2 14 ? -10.211 -33.102 41.512 1.00 79.39 ? 14 LEU B C 1 ATOM 4243 O O . LEU B 2 14 ? -9.375 -33.381 42.365 1.00 88.05 ? 14 LEU B O 1 ATOM 4244 C CB . LEU B 2 14 ? -10.022 -30.689 40.877 1.00 81.49 ? 14 LEU B CB 1 ATOM 4245 C CG . LEU B 2 14 ? -10.654 -29.534 40.085 1.00 85.22 ? 14 LEU B CG 1 ATOM 4246 C CD1 . LEU B 2 14 ? -11.604 -30.039 38.995 1.00 80.37 ? 14 LEU B CD1 1 ATOM 4247 C CD2 . LEU B 2 14 ? -11.354 -28.550 41.008 1.00 85.52 ? 14 LEU B CD2 1 ATOM 4248 N N . THR B 2 15 ? -10.553 -33.942 40.545 1.00 76.58 ? 15 THR B N 1 ATOM 4249 C CA . THR B 2 15 ? -9.949 -35.263 40.438 1.00 82.25 ? 15 THR B CA 1 ATOM 4250 C C . THR B 2 15 ? -9.642 -35.603 38.972 1.00 85.47 ? 15 THR B C 1 ATOM 4251 O O . THR B 2 15 ? -10.183 -34.983 38.055 1.00 84.99 ? 15 THR B O 1 ATOM 4252 C CB . THR B 2 15 ? -10.853 -36.346 41.090 1.00 83.79 ? 15 THR B CB 1 ATOM 4253 O OG1 . THR B 2 15 ? -10.146 -37.591 41.186 1.00 90.84 ? 15 THR B OG1 1 ATOM 4254 C CG2 . THR B 2 15 ? -12.132 -36.547 40.290 1.00 81.98 ? 15 THR B CG2 1 ATOM 4255 N N . ASN B 2 16 ? -8.764 -36.575 38.749 1.00 86.07 ? 16 ASN B N 1 ATOM 4256 C CA . ASN B 2 16 ? -8.386 -36.938 37.387 1.00 89.47 ? 16 ASN B CA 1 ATOM 4257 C C . ASN B 2 16 ? -9.172 -38.144 36.894 1.00 92.84 ? 16 ASN B C 1 ATOM 4258 O O . ASN B 2 16 ? -8.800 -39.289 37.149 1.00 92.48 ? 16 ASN B O 1 ATOM 4259 C CB . ASN B 2 16 ? -6.878 -37.199 37.286 1.00 90.71 ? 16 ASN B CB 1 ATOM 4260 C CG . ASN B 2 16 ? -6.356 -37.108 35.852 1.00 96.74 ? 16 ASN B CG 1 ATOM 4261 O OD1 . ASN B 2 16 ? -6.829 -37.809 34.948 1.00 93.21 ? 16 ASN B OD1 1 ATOM 4262 N ND2 . ASN B 2 16 ? -5.376 -36.236 35.641 1.00 94.12 ? 16 ASN B ND2 1 ATOM 4263 N N . CYS B 2 17 ? -10.263 -37.882 36.182 1.00 94.46 ? 17 CYS B N 1 ATOM 4264 C CA . CYS B 2 17 ? -11.112 -38.955 35.679 1.00 100.06 ? 17 CYS B CA 1 ATOM 4265 C C . CYS B 2 17 ? -10.441 -39.662 34.508 1.00 99.56 ? 17 CYS B C 1 ATOM 4266 O O . CYS B 2 17 ? -10.662 -40.850 34.277 1.00 99.45 ? 17 CYS B O 1 ATOM 4267 C CB . CYS B 2 17 ? -12.504 -38.422 35.306 1.00 102.03 ? 17 CYS B CB 1 ATOM 4268 S SG . CYS B 2 17 ? -13.502 -37.895 36.758 1.00 108.45 ? 17 CYS B SG 1 ATOM 4269 N N . GLY B 2 18 ? -9.604 -38.920 33.788 1.00 102.57 ? 18 GLY B N 1 ATOM 4270 C CA . GLY B 2 18 ? -8.803 -39.483 32.718 1.00 103.23 ? 18 GLY B CA 1 ATOM 4271 C C . GLY B 2 18 ? -9.572 -39.665 31.427 1.00 109.72 ? 18 GLY B C 1 ATOM 4272 O O . GLY B 2 18 ? -10.160 -38.711 30.903 1.00 108.14 ? 18 GLY B O 1 ATOM 4273 N N . GLU B 2 19 ? -9.565 -40.897 30.919 1.00 113.52 ? 19 GLU B N 1 ATOM 4274 C CA . GLU B 2 19 ? -10.236 -41.235 29.666 1.00 116.22 ? 19 GLU B CA 1 ATOM 4275 C C . GLU B 2 19 ? -11.692 -41.642 29.878 1.00 113.77 ? 19 GLU B C 1 ATOM 4276 O O . GLU B 2 19 ? -12.443 -41.823 28.918 1.00 111.62 ? 19 GLU B O 1 ATOM 4277 C CB . GLU B 2 19 ? -9.475 -42.342 28.931 1.00 120.72 ? 19 GLU B CB 1 ATOM 4278 C CG . GLU B 2 19 ? -8.118 -41.913 28.399 1.00 122.13 ? 19 GLU B CG 1 ATOM 4279 C CD . GLU B 2 19 ? -8.216 -40.753 27.425 1.00 126.45 ? 19 GLU B CD 1 ATOM 4280 O OE1 . GLU B 2 19 ? -8.229 -39.588 27.879 1.00 122.85 ? 19 GLU B OE1 1 ATOM 4281 O OE2 . GLU B 2 19 ? -8.282 -41.006 26.202 1.00 133.02 ? 19 GLU B OE2 1 ATOM 4282 N N . ASN B 2 20 ? -12.086 -41.789 31.138 1.00 109.92 ? 20 ASN B N 1 ATOM 4283 C CA . ASN B 2 20 ? -13.479 -42.058 31.461 1.00 103.90 ? 20 ASN B CA 1 ATOM 4284 C C . ASN B 2 20 ? -14.313 -40.792 31.301 1.00 97.85 ? 20 ASN B C 1 ATOM 4285 O O . ASN B 2 20 ? -13.790 -39.713 30.993 1.00 89.73 ? 20 ASN B O 1 ATOM 4286 C CB . ASN B 2 20 ? -13.606 -42.588 32.889 1.00 100.28 ? 20 ASN B CB 1 ATOM 4287 C CG . ASN B 2 20 ? -12.432 -43.455 33.288 1.00 111.87 ? 20 ASN B CG 1 ATOM 4288 O OD1 . ASN B 2 20 ? -11.805 -44.090 32.438 1.00 105.50 ? 20 ASN B OD1 1 ATOM 4289 N ND2 . ASN B 2 20 ? -12.121 -43.483 34.588 1.00 113.22 ? 20 ASN B ND2 1 ATOM 4290 N N . SER B 2 21 ? -15.616 -40.925 31.510 1.00 86.74 ? 21 SER B N 1 ATOM 4291 C CA . SER B 2 21 ? -16.490 -39.766 31.469 1.00 79.54 ? 21 SER B CA 1 ATOM 4292 C C . SER B 2 21 ? -16.733 -39.224 32.878 1.00 84.54 ? 21 SER B C 1 ATOM 4293 O O . SER B 2 21 ? -16.229 -39.758 33.876 1.00 76.98 ? 21 SER B O 1 ATOM 4294 C CB . SER B 2 21 ? -17.808 -40.114 30.773 1.00 76.30 ? 21 SER B CB 1 ATOM 4295 O OG . SER B 2 21 ? -18.112 -41.491 30.930 1.00 78.56 ? 21 SER B OG 1 ATOM 4296 N N . CYS B 2 22 ? -17.508 -38.152 32.949 1.00 81.25 ? 22 CYS B N 1 ATOM 4297 C CA . CYS B 2 22 ? -17.850 -37.534 34.214 1.00 71.84 ? 22 CYS B CA 1 ATOM 4298 C C . CYS B 2 22 ? -19.352 -37.599 34.455 1.00 75.74 ? 22 CYS B C 1 ATOM 4299 O O . CYS B 2 22 ? -20.105 -37.959 33.555 1.00 82.52 ? 22 CYS B O 1 ATOM 4300 C CB . CYS B 2 22 ? -17.363 -36.096 34.209 1.00 71.32 ? 22 CYS B CB 1 ATOM 4301 S SG . CYS B 2 22 ? -15.569 -36.030 34.160 1.00 92.85 ? 22 CYS B SG 1 ATOM 4302 N N . TYR B 2 23 ? -19.791 -37.279 35.669 1.00 78.13 ? 23 TYR B N 1 ATOM 4303 C CA . TYR B 2 23 ? -21.223 -37.227 35.942 1.00 69.30 ? 23 TYR B CA 1 ATOM 4304 C C . TYR B 2 23 ? -21.626 -36.177 36.964 1.00 68.95 ? 23 TYR B C 1 ATOM 4305 O O . TYR B 2 23 ? -20.868 -35.850 37.885 1.00 64.24 ? 23 TYR B O 1 ATOM 4306 C CB . TYR B 2 23 ? -21.767 -38.598 36.358 1.00 65.27 ? 23 TYR B CB 1 ATOM 4307 C CG . TYR B 2 23 ? -21.380 -39.042 37.742 1.00 68.30 ? 23 TYR B CG 1 ATOM 4308 C CD1 . TYR B 2 23 ? -20.317 -39.912 37.935 1.00 66.23 ? 23 TYR B CD1 1 ATOM 4309 C CD2 . TYR B 2 23 ? -22.090 -38.604 38.869 1.00 71.72 ? 23 TYR B CD2 1 ATOM 4310 C CE1 . TYR B 2 23 ? -19.963 -40.326 39.206 1.00 73.51 ? 23 TYR B CE1 1 ATOM 4311 C CE2 . TYR B 2 23 ? -21.737 -39.020 40.153 1.00 64.78 ? 23 TYR B CE2 1 ATOM 4312 C CZ . TYR B 2 23 ? -20.679 -39.880 40.307 1.00 62.59 ? 23 TYR B CZ 1 ATOM 4313 O OH . TYR B 2 23 ? -20.318 -40.307 41.547 1.00 66.66 ? 23 TYR B OH 1 ATOM 4314 N N . ARG B 2 24 ? -22.846 -35.680 36.779 1.00 61.86 ? 24 ARG B N 1 ATOM 4315 C CA . ARG B 2 24 ? -23.496 -34.773 37.697 1.00 62.40 ? 24 ARG B CA 1 ATOM 4316 C C . ARG B 2 24 ? -24.863 -35.355 38.082 1.00 68.76 ? 24 ARG B C 1 ATOM 4317 O O . ARG B 2 24 ? -25.830 -35.279 37.293 1.00 60.82 ? 24 ARG B O 1 ATOM 4318 C CB . ARG B 2 24 ? -23.660 -33.401 37.046 1.00 56.06 ? 24 ARG B CB 1 ATOM 4319 C CG . ARG B 2 24 ? -24.236 -32.307 37.947 1.00 56.74 ? 24 ARG B CG 1 ATOM 4320 C CD . ARG B 2 24 ? -24.271 -31.041 37.151 1.00 58.38 ? 24 ARG B CD 1 ATOM 4321 N NE . ARG B 2 24 ? -24.830 -29.858 37.792 1.00 48.10 ? 24 ARG B NE 1 ATOM 4322 C CZ . ARG B 2 24 ? -26.113 -29.687 38.085 1.00 49.58 ? 24 ARG B CZ 1 ATOM 4323 N NH1 . ARG B 2 24 ? -26.992 -30.660 37.857 1.00 54.66 ? 24 ARG B NH1 1 ATOM 4324 N NH2 . ARG B 2 24 ? -26.510 -28.539 38.623 1.00 46.65 ? 24 ARG B NH2 1 ATOM 4325 N N . LYS B 2 25 ? -24.916 -35.948 39.284 1.00 59.24 ? 25 LYS B N 1 ATOM 4326 C CA . LYS B 2 25 ? -26.153 -36.438 39.893 1.00 56.39 ? 25 LYS B CA 1 ATOM 4327 C C . LYS B 2 25 ? -26.891 -35.283 40.554 1.00 62.88 ? 25 LYS B C 1 ATOM 4328 O O . LYS B 2 25 ? -26.289 -34.446 41.226 1.00 62.24 ? 25 LYS B O 1 ATOM 4329 C CB . LYS B 2 25 ? -25.872 -37.488 40.963 1.00 56.91 ? 25 LYS B CB 1 ATOM 4330 C CG . LYS B 2 25 ? -25.574 -38.873 40.473 1.00 64.96 ? 25 LYS B CG 1 ATOM 4331 C CD . LYS B 2 25 ? -25.778 -39.889 41.594 1.00 64.46 ? 25 LYS B CD 1 ATOM 4332 C CE . LYS B 2 25 ? -24.955 -41.156 41.375 1.00 61.43 ? 25 LYS B CE 1 ATOM 4333 N NZ . LYS B 2 25 ? -25.394 -42.258 42.276 1.00 76.41 ? 25 LYS B NZ 1 ATOM 4334 N N . SER B 2 26 ? -28.202 -35.247 40.369 1.00 64.03 ? 26 SER B N 1 ATOM 4335 C CA . SER B 2 26 ? -29.024 -34.177 40.906 1.00 56.31 ? 26 SER B CA 1 ATOM 4336 C C . SER B 2 26 ? -30.451 -34.682 41.067 1.00 58.45 ? 26 SER B C 1 ATOM 4337 O O . SER B 2 26 ? -30.832 -35.694 40.490 1.00 62.84 ? 26 SER B O 1 ATOM 4338 C CB . SER B 2 26 ? -28.979 -32.936 40.002 1.00 52.63 ? 26 SER B CB 1 ATOM 4339 O OG . SER B 2 26 ? -29.573 -33.181 38.727 1.00 71.29 ? 26 SER B OG 1 ATOM 4340 N N . ARG B 2 27 ? -31.233 -33.999 41.885 1.00 65.03 ? 27 ARG B N 1 ATOM 4341 C CA . ARG B 2 27 ? -32.649 -34.291 41.955 1.00 65.86 ? 27 ARG B CA 1 ATOM 4342 C C . ARG B 2 27 ? -33.244 -33.884 40.593 1.00 64.10 ? 27 ARG B C 1 ATOM 4343 O O . ARG B 2 27 ? -32.994 -32.780 40.099 1.00 66.29 ? 27 ARG B O 1 ATOM 4344 C CB . ARG B 2 27 ? -33.283 -33.538 43.128 1.00 57.27 ? 27 ARG B CB 1 ATOM 4345 C CG . ARG B 2 27 ? -34.765 -33.741 43.263 1.00 62.55 ? 27 ARG B CG 1 ATOM 4346 C CD . ARG B 2 27 ? -35.356 -33.025 44.481 1.00 47.68 ? 27 ARG B CD 1 ATOM 4347 N NE . ARG B 2 27 ? -36.561 -33.725 44.910 1.00 47.22 ? 27 ARG B NE 1 ATOM 4348 C CZ . ARG B 2 27 ? -37.798 -33.360 44.604 1.00 52.79 ? 27 ARG B CZ 1 ATOM 4349 N NH1 . ARG B 2 27 ? -38.015 -32.279 43.878 1.00 53.41 ? 27 ARG B NH1 1 ATOM 4350 N NH2 . ARG B 2 27 ? -38.823 -34.076 45.043 1.00 63.81 ? 27 ARG B NH2 1 ATOM 4351 N N . ARG B 2 28 ? -33.987 -34.798 39.969 1.00 65.03 ? 28 ARG B N 1 ATOM 4352 C CA . ARG B 2 28 ? -34.559 -34.561 38.648 1.00 60.56 ? 28 ARG B CA 1 ATOM 4353 C C . ARG B 2 28 ? -35.502 -33.363 38.629 1.00 59.63 ? 28 ARG B C 1 ATOM 4354 O O . ARG B 2 28 ? -35.360 -32.462 37.803 1.00 65.46 ? 28 ARG B O 1 ATOM 4355 C CB . ARG B 2 28 ? -35.293 -35.815 38.155 1.00 67.57 ? 28 ARG B CB 1 ATOM 4356 C CG . ARG B 2 28 ? -35.806 -35.705 36.723 1.00 63.81 ? 28 ARG B CG 1 ATOM 4357 C CD . ARG B 2 28 ? -36.515 -36.973 36.266 1.00 65.50 ? 28 ARG B CD 1 ATOM 4358 N NE . ARG B 2 28 ? -35.626 -38.131 36.241 1.00 68.32 ? 28 ARG B NE 1 ATOM 4359 C CZ . ARG B 2 28 ? -34.745 -38.376 35.273 1.00 63.93 ? 28 ARG B CZ 1 ATOM 4360 N NH1 . ARG B 2 28 ? -34.628 -37.534 34.256 1.00 66.54 ? 28 ARG B NH1 1 ATOM 4361 N NH2 . ARG B 2 28 ? -33.969 -39.453 35.329 1.00 60.93 ? 28 ARG B NH2 1 ATOM 4362 N N . HIS B 2 29 ? -36.474 -33.365 39.535 1.00 57.34 ? 29 HIS B N 1 ATOM 4363 C CA . HIS B 2 29 ? -37.442 -32.283 39.621 1.00 57.17 ? 29 HIS B CA 1 ATOM 4364 C C . HIS B 2 29 ? -37.020 -31.262 40.671 1.00 58.34 ? 29 HIS B C 1 ATOM 4365 O O . HIS B 2 29 ? -36.288 -31.591 41.596 1.00 61.87 ? 29 HIS B O 1 ATOM 4366 C CB . HIS B 2 29 ? -38.824 -32.848 39.938 1.00 63.88 ? 29 HIS B CB 1 ATOM 4367 C CG . HIS B 2 29 ? -39.297 -33.858 38.944 1.00 69.84 ? 29 HIS B CG 1 ATOM 4368 N ND1 . HIS B 2 29 ? -39.579 -35.163 39.285 1.00 66.49 ? 29 HIS B ND1 1 ATOM 4369 C CD2 . HIS B 2 29 ? -39.511 -33.762 37.609 1.00 71.47 ? 29 HIS B CD2 1 ATOM 4370 C CE1 . HIS B 2 29 ? -39.955 -35.825 38.206 1.00 81.07 ? 29 HIS B CE1 1 ATOM 4371 N NE2 . HIS B 2 29 ? -39.922 -34.998 37.175 1.00 78.82 ? 29 HIS B NE2 1 ATOM 4372 N N . PRO B 2 30 ? -37.450 -30.003 40.510 1.00 64.67 ? 30 PRO B N 1 ATOM 4373 C CA . PRO B 2 30 ? -37.122 -28.942 41.478 1.00 65.33 ? 30 PRO B CA 1 ATOM 4374 C C . PRO B 2 30 ? -37.586 -29.238 42.911 1.00 59.12 ? 30 PRO B C 1 ATOM 4375 O O . PRO B 2 30 ? -38.684 -29.745 43.090 1.00 63.52 ? 30 PRO B O 1 ATOM 4376 C CB . PRO B 2 30 ? -37.838 -27.703 40.907 1.00 66.43 ? 30 PRO B CB 1 ATOM 4377 C CG . PRO B 2 30 ? -38.630 -28.180 39.724 1.00 59.65 ? 30 PRO B CG 1 ATOM 4378 C CD . PRO B 2 30 ? -38.031 -29.460 39.272 1.00 57.26 ? 30 PRO B CD 1 ATOM 4379 N N . PRO B 2 31 ? -36.754 -28.933 43.927 1.00 61.62 ? 31 PRO B N 1 ATOM 4380 C CA . PRO B 2 31 ? -35.459 -28.250 43.853 1.00 57.02 ? 31 PRO B CA 1 ATOM 4381 C C . PRO B 2 31 ? -34.365 -29.179 43.336 1.00 54.12 ? 31 PRO B C 1 ATOM 4382 O O . PRO B 2 31 ? -34.246 -30.312 43.785 1.00 52.94 ? 31 PRO B O 1 ATOM 4383 C CB . PRO B 2 31 ? -35.176 -27.869 45.311 1.00 53.39 ? 31 PRO B CB 1 ATOM 4384 C CG . PRO B 2 31 ? -36.180 -28.633 46.162 1.00 53.95 ? 31 PRO B CG 1 ATOM 4385 C CD . PRO B 2 31 ? -36.978 -29.520 45.259 1.00 60.05 ? 31 PRO B CD 1 ATOM 4386 N N . LYS B 2 32 ? -33.570 -28.701 42.388 1.00 59.17 ? 32 LYS B N 1 ATOM 4387 C CA . LYS B 2 32 ? -32.633 -29.590 41.716 1.00 62.53 ? 32 LYS B CA 1 ATOM 4388 C C . LYS B 2 32 ? -31.298 -29.640 42.423 1.00 61.19 ? 32 LYS B C 1 ATOM 4389 O O . LYS B 2 32 ? -30.273 -29.253 41.864 1.00 63.46 ? 32 LYS B O 1 ATOM 4390 C CB . LYS B 2 32 ? -32.479 -29.215 40.248 1.00 55.08 ? 32 LYS B CB 1 ATOM 4391 C CG . LYS B 2 32 ? -33.790 -29.313 39.482 1.00 56.81 ? 32 LYS B CG 1 ATOM 4392 C CD . LYS B 2 32 ? -33.577 -29.313 37.965 1.00 52.00 ? 32 LYS B CD 1 ATOM 4393 C CE . LYS B 2 32 ? -34.905 -29.150 37.212 1.00 50.04 ? 32 LYS B CE 1 ATOM 4394 N NZ . LYS B 2 32 ? -34.710 -29.207 35.742 1.00 66.99 ? 32 LYS B NZ 1 ATOM 4395 N N . MET B 2 33 ? -31.327 -30.148 43.651 1.00 50.17 ? 33 MET B N 1 ATOM 4396 C CA . MET B 2 33 ? -30.131 -30.255 44.470 1.00 56.51 ? 33 MET B CA 1 ATOM 4397 C C . MET B 2 33 ? -29.109 -31.200 43.846 1.00 55.05 ? 33 MET B C 1 ATOM 4398 O O . MET B 2 33 ? -29.438 -32.328 43.490 1.00 52.33 ? 33 MET B O 1 ATOM 4399 C CB . MET B 2 33 ? -30.495 -30.745 45.882 1.00 53.75 ? 33 MET B CB 1 ATOM 4400 C CG . MET B 2 33 ? -31.685 -30.026 46.503 1.00 58.91 ? 33 MET B CG 1 ATOM 4401 S SD . MET B 2 33 ? -31.475 -28.229 46.572 1.00 61.17 ? 33 MET B SD 1 ATOM 4402 C CE . MET B 2 33 ? -30.179 -28.098 47.799 1.00 55.48 ? 33 MET B CE 1 ATOM 4403 N N . VAL B 2 34 ? -27.868 -30.744 43.734 1.00 47.61 ? 34 VAL B N 1 ATOM 4404 C CA . VAL B 2 34 ? -26.783 -31.631 43.344 1.00 54.85 ? 34 VAL B CA 1 ATOM 4405 C C . VAL B 2 34 ? -26.431 -32.626 44.455 1.00 57.31 ? 34 VAL B C 1 ATOM 4406 O O . VAL B 2 34 ? -26.129 -32.226 45.581 1.00 63.89 ? 34 VAL B O 1 ATOM 4407 C CB . VAL B 2 34 ? -25.522 -30.850 42.935 1.00 57.81 ? 34 VAL B CB 1 ATOM 4408 C CG1 . VAL B 2 34 ? -24.440 -31.820 42.459 1.00 52.54 ? 34 VAL B CG1 1 ATOM 4409 C CG2 . VAL B 2 34 ? -25.855 -29.809 41.852 1.00 52.17 ? 34 VAL B CG2 1 ATOM 4410 N N . LEU B 2 35 ? -26.457 -33.917 44.128 1.00 54.37 ? 35 LEU B N 1 ATOM 4411 C CA . LEU B 2 35 ? -26.175 -34.980 45.096 1.00 57.53 ? 35 LEU B CA 1 ATOM 4412 C C . LEU B 2 35 ? -24.845 -35.718 44.874 1.00 61.12 ? 35 LEU B C 1 ATOM 4413 O O . LEU B 2 35 ? -24.502 -36.644 45.616 1.00 58.28 ? 35 LEU B O 1 ATOM 4414 C CB . LEU B 2 35 ? -27.304 -36.014 45.071 1.00 58.62 ? 35 LEU B CB 1 ATOM 4415 C CG . LEU B 2 35 ? -28.739 -35.519 45.219 1.00 55.78 ? 35 LEU B CG 1 ATOM 4416 C CD1 . LEU B 2 35 ? -29.638 -36.715 45.352 1.00 58.64 ? 35 LEU B CD1 1 ATOM 4417 C CD2 . LEU B 2 35 ? -28.889 -34.611 46.425 1.00 57.05 ? 35 LEU B CD2 1 ATOM 4418 N N . GLY B 2 36 ? -24.114 -35.348 43.831 1.00 70.09 ? 36 GLY B N 1 ATOM 4419 C CA . GLY B 2 36 ? -22.899 -36.070 43.496 1.00 65.66 ? 36 GLY B CA 1 ATOM 4420 C C . GLY B 2 36 ? -22.236 -35.610 42.213 1.00 62.01 ? 36 GLY B C 1 ATOM 4421 O O . GLY B 2 36 ? -22.876 -35.092 41.316 1.00 60.76 ? 36 GLY B O 1 ATOM 4422 N N . ARG B 2 37 ? -20.925 -35.782 42.160 1.00 60.89 ? 37 ARG B N 1 ATOM 4423 C CA . ARG B 2 37 ? -20.135 -35.498 40.991 1.00 55.11 ? 37 ARG B CA 1 ATOM 4424 C C . ARG B 2 37 ? -18.978 -36.452 41.105 1.00 63.53 ? 37 ARG B C 1 ATOM 4425 O O . ARG B 2 37 ? -18.475 -36.687 42.199 1.00 58.84 ? 37 ARG B O 1 ATOM 4426 C CB . ARG B 2 37 ? -19.625 -34.057 40.975 1.00 55.43 ? 37 ARG B CB 1 ATOM 4427 C CG . ARG B 2 37 ? -20.633 -33.017 40.508 1.00 56.83 ? 37 ARG B CG 1 ATOM 4428 C CD . ARG B 2 37 ? -19.989 -31.641 40.420 1.00 55.99 ? 37 ARG B CD 1 ATOM 4429 N NE . ARG B 2 37 ? -20.933 -30.568 40.097 1.00 58.66 ? 37 ARG B NE 1 ATOM 4430 C CZ . ARG B 2 37 ? -21.571 -29.819 41.003 1.00 66.59 ? 37 ARG B CZ 1 ATOM 4431 N NH1 . ARG B 2 37 ? -21.375 -30.012 42.313 1.00 58.18 ? 37 ARG B NH1 1 ATOM 4432 N NH2 . ARG B 2 37 ? -22.405 -28.859 40.602 1.00 58.85 ? 37 ARG B NH2 1 ATOM 4433 N N . GLY B 2 38 ? -18.558 -37.018 39.980 1.00 72.88 ? 38 GLY B N 1 ATOM 4434 C CA . GLY B 2 38 ? -17.468 -37.966 40.005 1.00 64.48 ? 38 GLY B CA 1 ATOM 4435 C C . GLY B 2 38 ? -17.145 -38.492 38.640 1.00 72.17 ? 38 GLY B C 1 ATOM 4436 O O . GLY B 2 38 ? -17.456 -37.865 37.629 1.00 72.85 ? 38 GLY B O 1 ATOM 4437 N N . CYS B 2 39 ? -16.514 -39.658 38.626 1.00 77.35 ? 39 CYS B N 1 ATOM 4438 C CA . CYS B 2 39 ? -16.056 -40.280 37.397 1.00 65.28 ? 39 CYS B CA 1 ATOM 4439 C C . CYS B 2 39 ? -17.023 -41.362 36.983 1.00 72.30 ? 39 CYS B C 1 ATOM 4440 O O . CYS B 2 39 ? -17.693 -41.954 37.827 1.00 77.53 ? 39 CYS B O 1 ATOM 4441 C CB . CYS B 2 39 ? -14.663 -40.886 37.595 1.00 73.61 ? 39 CYS B CB 1 ATOM 4442 S SG . CYS B 2 39 ? -13.341 -39.655 37.785 1.00 86.74 ? 39 CYS B SG 1 ATOM 4443 N N . GLY B 2 40 ? -17.091 -41.620 35.682 1.00 65.59 ? 40 GLY B N 1 ATOM 4444 C CA . GLY B 2 40 ? -17.925 -42.680 35.166 1.00 58.80 ? 40 GLY B CA 1 ATOM 4445 C C . GLY B 2 40 ? -19.243 -42.149 34.648 1.00 70.65 ? 40 GLY B C 1 ATOM 4446 O O . GLY B 2 40 ? -19.431 -40.938 34.471 1.00 64.56 ? 40 GLY B O 1 ATOM 4447 N N . CYS B 2 41 ? -20.164 -43.069 34.398 1.00 70.79 ? 41 CYS B N 1 ATOM 4448 C CA . CYS B 2 41 ? -21.486 -42.709 33.911 1.00 74.99 ? 41 CYS B CA 1 ATOM 4449 C C . CYS B 2 41 ? -22.532 -43.656 34.478 1.00 74.15 ? 41 CYS B C 1 ATOM 4450 O O . CYS B 2 41 ? -22.865 -44.672 33.849 1.00 74.56 ? 41 CYS B O 1 ATOM 4451 C CB . CYS B 2 41 ? -21.527 -42.754 32.384 1.00 80.36 ? 41 CYS B CB 1 ATOM 4452 S SG . CYS B 2 41 ? -23.070 -42.112 31.717 1.00 92.12 ? 41 CYS B SG 1 ATOM 4453 N N . PRO B 2 42 ? -23.051 -43.325 35.674 1.00 69.20 ? 42 PRO B N 1 ATOM 4454 C CA . PRO B 2 42 ? -23.963 -44.220 36.387 1.00 60.37 ? 42 PRO B CA 1 ATOM 4455 C C . PRO B 2 42 ? -25.411 -43.982 36.000 1.00 55.40 ? 42 PRO B C 1 ATOM 4456 O O . PRO B 2 42 ? -25.774 -42.863 35.614 1.00 54.71 ? 42 PRO B O 1 ATOM 4457 C CB . PRO B 2 42 ? -23.731 -43.840 37.856 1.00 60.09 ? 42 PRO B CB 1 ATOM 4458 C CG . PRO B 2 42 ? -23.371 -42.378 37.808 1.00 59.50 ? 42 PRO B CG 1 ATOM 4459 C CD . PRO B 2 42 ? -22.718 -42.123 36.468 1.00 71.47 ? 42 PRO B CD 1 ATOM 4460 N N . PRO B 2 43 ? -26.232 -45.033 36.095 1.00 49.40 ? 43 PRO B N 1 ATOM 4461 C CA . PRO B 2 43 ? -27.688 -44.902 35.961 1.00 53.90 ? 43 PRO B CA 1 ATOM 4462 C C . PRO B 2 43 ? -28.306 -43.899 36.937 1.00 65.27 ? 43 PRO B C 1 ATOM 4463 O O . PRO B 2 43 ? -27.887 -43.790 38.104 1.00 69.49 ? 43 PRO B O 1 ATOM 4464 C CB . PRO B 2 43 ? -28.211 -46.318 36.261 1.00 51.73 ? 43 PRO B CB 1 ATOM 4465 C CG . PRO B 2 43 ? -27.021 -47.113 36.738 1.00 58.01 ? 43 PRO B CG 1 ATOM 4466 C CD . PRO B 2 43 ? -25.801 -46.432 36.221 1.00 48.08 ? 43 PRO B CD 1 ATOM 4467 N N . GLY B 2 44 ? -29.293 -43.162 36.437 1.00 65.81 ? 44 GLY B N 1 ATOM 4468 C CA . GLY B 2 44 ? -30.156 -42.341 37.267 1.00 64.98 ? 44 GLY B CA 1 ATOM 4469 C C . GLY B 2 44 ? -31.473 -43.050 37.505 1.00 67.56 ? 44 GLY B C 1 ATOM 4470 O O . GLY B 2 44 ? -31.544 -44.276 37.427 1.00 68.20 ? 44 GLY B O 1 ATOM 4471 N N . ASP B 2 45 ? -32.523 -42.285 37.778 1.00 67.37 ? 45 ASP B N 1 ATOM 4472 C CA . ASP B 2 45 ? -33.808 -42.879 38.102 1.00 61.56 ? 45 ASP B CA 1 ATOM 4473 C C . ASP B 2 45 ? -34.922 -41.836 38.014 1.00 66.83 ? 45 ASP B C 1 ATOM 4474 O O . ASP B 2 45 ? -34.723 -40.744 37.473 1.00 68.10 ? 45 ASP B O 1 ATOM 4475 C CB . ASP B 2 45 ? -33.738 -43.502 39.493 1.00 61.52 ? 45 ASP B CB 1 ATOM 4476 C CG . ASP B 2 45 ? -34.755 -44.605 39.695 1.00 73.02 ? 45 ASP B CG 1 ATOM 4477 O OD1 . ASP B 2 45 ? -35.881 -44.489 39.164 1.00 73.28 ? 45 ASP B OD1 1 ATOM 4478 O OD2 . ASP B 2 45 ? -34.426 -45.587 40.394 1.00 72.10 ? 45 ASP B OD2 1 ATOM 4479 N N . ASP B 2 46 ? -36.100 -42.181 38.523 1.00 66.16 ? 46 ASP B N 1 ATOM 4480 C CA . ASP B 2 46 ? -37.229 -41.254 38.535 1.00 76.26 ? 46 ASP B CA 1 ATOM 4481 C C . ASP B 2 46 ? -36.896 -39.954 39.288 1.00 81.86 ? 46 ASP B C 1 ATOM 4482 O O . ASP B 2 46 ? -37.124 -38.854 38.765 1.00 79.45 ? 46 ASP B O 1 ATOM 4483 C CB . ASP B 2 46 ? -38.463 -41.920 39.158 1.00 83.18 ? 46 ASP B CB 1 ATOM 4484 C CG . ASP B 2 46 ? -38.889 -43.188 38.421 1.00 86.25 ? 46 ASP B CG 1 ATOM 4485 O OD1 . ASP B 2 46 ? -38.718 -43.262 37.178 1.00 88.99 ? 46 ASP B OD1 1 ATOM 4486 O OD2 . ASP B 2 46 ? -39.400 -44.114 39.093 1.00 86.13 ? 46 ASP B OD2 1 ATOM 4487 N N . ASN B 2 47 ? -36.344 -40.091 40.502 1.00 70.28 ? 47 ASN B N 1 ATOM 4488 C CA . ASN B 2 47 ? -35.965 -38.942 41.328 1.00 71.63 ? 47 ASN B CA 1 ATOM 4489 C C . ASN B 2 47 ? -34.550 -38.424 41.077 1.00 69.73 ? 47 ASN B C 1 ATOM 4490 O O . ASN B 2 47 ? -34.287 -37.236 41.270 1.00 68.15 ? 47 ASN B O 1 ATOM 4491 C CB . ASN B 2 47 ? -36.130 -39.257 42.823 1.00 76.46 ? 47 ASN B CB 1 ATOM 4492 C CG . ASN B 2 47 ? -37.473 -39.877 43.141 1.00 77.67 ? 47 ASN B CG 1 ATOM 4493 O OD1 . ASN B 2 47 ? -38.464 -39.628 42.448 1.00 87.51 ? 47 ASN B OD1 1 ATOM 4494 N ND2 . ASN B 2 47 ? -37.514 -40.698 44.184 1.00 67.42 ? 47 ASN B ND2 1 ATOM 4495 N N . LEU B 2 48 ? -33.646 -39.314 40.661 1.00 70.70 ? 48 LEU B N 1 ATOM 4496 C CA . LEU B 2 48 ? -32.260 -38.934 40.339 1.00 67.79 ? 48 LEU B CA 1 ATOM 4497 C C . LEU B 2 48 ? -31.995 -38.715 38.838 1.00 65.76 ? 48 LEU B C 1 ATOM 4498 O O . LEU B 2 48 ? -32.108 -39.642 38.040 1.00 68.31 ? 48 LEU B O 1 ATOM 4499 C CB . LEU B 2 48 ? -31.273 -39.979 40.875 1.00 62.35 ? 48 LEU B CB 1 ATOM 4500 C CG . LEU B 2 48 ? -31.240 -40.176 42.394 1.00 75.16 ? 48 LEU B CG 1 ATOM 4501 C CD1 . LEU B 2 48 ? -30.040 -41.003 42.880 1.00 61.16 ? 48 LEU B CD1 1 ATOM 4502 C CD2 . LEU B 2 48 ? -31.261 -38.814 43.054 1.00 76.74 ? 48 LEU B CD2 1 ATOM 4503 N N . GLU B 2 49 ? -31.627 -37.494 38.462 1.00 60.10 ? 49 GLU B N 1 ATOM 4504 C CA . GLU B 2 49 ? -31.118 -37.240 37.116 1.00 61.87 ? 49 GLU B CA 1 ATOM 4505 C C . GLU B 2 49 ? -29.591 -37.263 37.050 1.00 66.22 ? 49 GLU B C 1 ATOM 4506 O O . GLU B 2 49 ? -28.923 -36.573 37.818 1.00 66.05 ? 49 GLU B O 1 ATOM 4507 C CB . GLU B 2 49 ? -31.619 -35.894 36.579 1.00 68.41 ? 49 GLU B CB 1 ATOM 4508 C CG . GLU B 2 49 ? -31.011 -35.519 35.223 1.00 66.13 ? 49 GLU B CG 1 ATOM 4509 C CD . GLU B 2 49 ? -31.576 -34.231 34.652 1.00 78.20 ? 49 GLU B CD 1 ATOM 4510 O OE1 . GLU B 2 49 ? -32.224 -33.470 35.409 1.00 80.80 ? 49 GLU B OE1 1 ATOM 4511 O OE2 . GLU B 2 49 ? -31.374 -33.979 33.438 1.00 90.69 ? 49 GLU B OE2 1 ATOM 4512 N N . VAL B 2 50 ? -29.047 -38.036 36.111 1.00 67.35 ? 50 VAL B N 1 ATOM 4513 C CA . VAL B 2 50 ? -27.609 -38.043 35.836 1.00 64.28 ? 50 VAL B CA 1 ATOM 4514 C C . VAL B 2 50 ? -27.276 -37.380 34.490 1.00 66.33 ? 50 VAL B C 1 ATOM 4515 O O . VAL B 2 50 ? -27.888 -37.685 33.472 1.00 69.74 ? 50 VAL B O 1 ATOM 4516 C CB . VAL B 2 50 ? -27.051 -39.479 35.833 1.00 59.48 ? 50 VAL B CB 1 ATOM 4517 C CG1 . VAL B 2 50 ? -25.537 -39.469 35.742 1.00 59.09 ? 50 VAL B CG1 1 ATOM 4518 C CG2 . VAL B 2 50 ? -27.487 -40.205 37.071 1.00 59.64 ? 50 VAL B CG2 1 ATOM 4519 N N . LYS B 2 51 ? -26.303 -36.475 34.498 1.00 66.82 ? 51 LYS B N 1 ATOM 4520 C CA . LYS B 2 51 ? -25.787 -35.863 33.278 1.00 60.05 ? 51 LYS B CA 1 ATOM 4521 C C . LYS B 2 51 ? -24.328 -36.272 33.026 1.00 69.82 ? 51 LYS B C 1 ATOM 4522 O O . LYS B 2 51 ? -23.456 -35.997 33.843 1.00 66.07 ? 51 LYS B O 1 ATOM 4523 C CB . LYS B 2 51 ? -25.901 -34.337 33.353 1.00 56.56 ? 51 LYS B CB 1 ATOM 4524 C CG . LYS B 2 51 ? -27.321 -33.840 33.523 1.00 62.02 ? 51 LYS B CG 1 ATOM 4525 C CD . LYS B 2 51 ? -27.411 -32.319 33.700 1.00 61.81 ? 51 LYS B CD 1 ATOM 4526 C CE . LYS B 2 51 ? -28.844 -31.927 34.080 1.00 71.99 ? 51 LYS B CE 1 ATOM 4527 N NZ . LYS B 2 51 ? -29.106 -30.461 34.138 1.00 77.81 ? 51 LYS B NZ 1 ATOM 4528 N N . CYS B 2 52 ? -24.066 -36.928 31.892 1.00 82.95 ? 52 CYS B N 1 ATOM 4529 C CA . CYS B 2 52 ? -22.707 -37.359 31.534 1.00 71.27 ? 52 CYS B CA 1 ATOM 4530 C C . CYS B 2 52 ? -22.067 -36.414 30.528 1.00 73.46 ? 52 CYS B C 1 ATOM 4531 O O . CYS B 2 52 ? -22.766 -35.746 29.761 1.00 76.85 ? 52 CYS B O 1 ATOM 4532 C CB . CYS B 2 52 ? -22.706 -38.779 30.965 1.00 78.70 ? 52 CYS B CB 1 ATOM 4533 S SG . CYS B 2 52 ? -22.772 -40.138 32.182 1.00 96.72 ? 52 CYS B SG 1 ATOM 4534 N N . CYS B 2 53 ? -20.736 -36.359 30.546 1.00 69.86 ? 53 CYS B N 1 ATOM 4535 C CA . CYS B 2 53 ? -19.968 -35.566 29.587 1.00 80.13 ? 53 CYS B CA 1 ATOM 4536 C C . CYS B 2 53 ? -18.518 -36.092 29.468 1.00 87.12 ? 53 CYS B C 1 ATOM 4537 O O . CYS B 2 53 ? -18.094 -36.926 30.276 1.00 79.58 ? 53 CYS B O 1 ATOM 4538 C CB . CYS B 2 53 ? -20.009 -34.075 29.947 1.00 68.26 ? 53 CYS B CB 1 ATOM 4539 S SG . CYS B 2 53 ? -18.695 -33.545 31.083 1.00 109.69 ? 53 CYS B SG 1 ATOM 4540 N N . THR B 2 54 ? -17.775 -35.623 28.455 1.00 89.91 ? 54 THR B N 1 ATOM 4541 C CA . THR B 2 54 ? -16.426 -36.140 28.167 1.00 76.75 ? 54 THR B CA 1 ATOM 4542 C C . THR B 2 54 ? -15.337 -35.059 28.135 1.00 78.67 ? 54 THR B C 1 ATOM 4543 O O . THR B 2 54 ? -14.158 -35.349 28.362 1.00 78.30 ? 54 THR B O 1 ATOM 4544 C CB . THR B 2 54 ? -16.386 -36.937 26.838 1.00 80.31 ? 54 THR B CB 1 ATOM 4545 O OG1 . THR B 2 54 ? -16.714 -36.075 25.737 1.00 83.77 ? 54 THR B OG1 1 ATOM 4546 C CG2 . THR B 2 54 ? -17.365 -38.107 26.877 1.00 80.96 ? 54 THR B CG2 1 ATOM 4547 N N . SER B 2 55 ? -15.743 -33.817 27.871 1.00 78.10 ? 55 SER B N 1 ATOM 4548 C CA . SER B 2 55 ? -14.815 -32.694 27.725 1.00 74.58 ? 55 SER B CA 1 ATOM 4549 C C . SER B 2 55 ? -15.568 -31.352 27.785 1.00 72.93 ? 55 SER B C 1 ATOM 4550 O O . SER B 2 55 ? -16.786 -31.301 27.556 1.00 68.37 ? 55 SER B O 1 ATOM 4551 C CB . SER B 2 55 ? -14.069 -32.814 26.391 1.00 76.46 ? 55 SER B CB 1 ATOM 4552 O OG . SER B 2 55 ? -14.984 -32.818 25.311 1.00 66.60 ? 55 SER B OG 1 ATOM 4553 N N . PRO B 2 56 ? -14.859 -30.258 28.111 1.00 69.69 ? 56 PRO B N 1 ATOM 4554 C CA . PRO B 2 56 ? -13.456 -30.201 28.527 1.00 77.40 ? 56 PRO B CA 1 ATOM 4555 C C . PRO B 2 56 ? -13.328 -30.491 30.023 1.00 92.27 ? 56 PRO B C 1 ATOM 4556 O O . PRO B 2 56 ? -14.083 -31.288 30.586 1.00 93.45 ? 56 PRO B O 1 ATOM 4557 C CB . PRO B 2 56 ? -13.087 -28.742 28.269 1.00 77.99 ? 56 PRO B CB 1 ATOM 4558 C CG . PRO B 2 56 ? -14.355 -27.997 28.531 1.00 65.87 ? 56 PRO B CG 1 ATOM 4559 C CD . PRO B 2 56 ? -15.468 -28.914 28.054 1.00 69.45 ? 56 PRO B CD 1 ATOM 4560 N N . ASP B 2 57 ? -12.371 -29.838 30.669 1.00 91.72 ? 57 ASP B N 1 ATOM 4561 C CA . ASP B 2 57 ? -12.200 -29.991 32.102 1.00 87.06 ? 57 ASP B CA 1 ATOM 4562 C C . ASP B 2 57 ? -13.317 -29.265 32.842 1.00 92.72 ? 57 ASP B C 1 ATOM 4563 O O . ASP B 2 57 ? -13.881 -28.297 32.314 1.00 90.85 ? 57 ASP B O 1 ATOM 4564 C CB . ASP B 2 57 ? -10.830 -29.472 32.532 1.00 86.07 ? 57 ASP B CB 1 ATOM 4565 C CG . ASP B 2 57 ? -9.707 -30.390 32.101 1.00 88.70 ? 57 ASP B CG 1 ATOM 4566 O OD1 . ASP B 2 57 ? -10.005 -31.507 31.605 1.00 84.93 ? 57 ASP B OD1 1 ATOM 4567 O OD2 . ASP B 2 57 ? -8.533 -30.000 32.276 1.00 84.86 ? 57 ASP B OD2 1 ATOM 4568 N N . LYS B 2 58 ? -13.635 -29.749 34.046 1.00 89.83 ? 58 LYS B N 1 ATOM 4569 C CA . LYS B 2 58 ? -14.686 -29.178 34.890 1.00 80.68 ? 58 LYS B CA 1 ATOM 4570 C C . LYS B 2 58 ? -16.036 -29.138 34.175 1.00 83.42 ? 58 LYS B C 1 ATOM 4571 O O . LYS B 2 58 ? -16.774 -28.152 34.270 1.00 82.08 ? 58 LYS B O 1 ATOM 4572 C CB . LYS B 2 58 ? -14.308 -27.769 35.343 1.00 76.56 ? 58 LYS B CB 1 ATOM 4573 C CG . LYS B 2 58 ? -12.944 -27.660 35.972 1.00 79.36 ? 58 LYS B CG 1 ATOM 4574 C CD . LYS B 2 58 ? -12.620 -26.211 36.252 1.00 80.05 ? 58 LYS B CD 1 ATOM 4575 C CE . LYS B 2 58 ? -11.267 -26.070 36.907 1.00 87.02 ? 58 LYS B CE 1 ATOM 4576 N NZ . LYS B 2 58 ? -10.885 -24.641 37.010 1.00 94.36 ? 58 LYS B NZ 1 ATOM 4577 N N . CYS B 2 59 ? -16.361 -30.204 33.455 1.00 82.47 ? 59 CYS B N 1 ATOM 4578 C CA . CYS B 2 59 ? -17.576 -30.203 32.643 1.00 88.69 ? 59 CYS B CA 1 ATOM 4579 C C . CYS B 2 59 ? -18.810 -30.699 33.410 1.00 78.65 ? 59 CYS B C 1 ATOM 4580 O O . CYS B 2 59 ? -19.943 -30.445 32.991 1.00 73.09 ? 59 CYS B O 1 ATOM 4581 C CB . CYS B 2 59 ? -17.370 -30.997 31.341 1.00 81.08 ? 59 CYS B CB 1 ATOM 4582 S SG . CYS B 2 59 ? -16.881 -32.741 31.566 1.00 88.55 ? 59 CYS B SG 1 ATOM 4583 N N . ASN B 2 60 ? -18.588 -31.394 34.528 1.00 76.18 ? 60 ASN B N 1 ATOM 4584 C CA . ASN B 2 60 ? -19.697 -31.842 35.379 1.00 69.96 ? 60 ASN B CA 1 ATOM 4585 C C . ASN B 2 60 ? -20.221 -30.801 36.381 1.00 68.12 ? 60 ASN B C 1 ATOM 4586 O O . ASN B 2 60 ? -21.060 -31.124 37.227 1.00 72.40 ? 60 ASN B O 1 ATOM 4587 C CB . ASN B 2 60 ? -19.407 -33.191 36.069 1.00 63.14 ? 60 ASN B CB 1 ATOM 4588 C CG . ASN B 2 60 ? -18.141 -33.178 36.909 1.00 69.51 ? 60 ASN B CG 1 ATOM 4589 O OD1 . ASN B 2 60 ? -17.516 -32.134 37.117 1.00 67.12 ? 60 ASN B OD1 1 ATOM 4590 N ND2 . ASN B 2 60 ? -17.760 -34.354 37.407 1.00 69.18 ? 60 ASN B ND2 1 ATOM 4591 N N . TYR B 2 61 ? -19.738 -29.561 36.266 1.00 66.12 ? 61 TYR B N 1 ATOM 4592 C CA . TYR B 2 61 ? -20.234 -28.425 37.056 1.00 67.75 ? 61 TYR B CA 1 ATOM 4593 C C . TYR B 2 61 ? -21.736 -28.199 36.839 1.00 74.95 ? 61 TYR B C 1 ATOM 4594 O O . TYR B 2 61 ? -22.518 -28.100 37.801 1.00 66.21 ? 61 TYR B O 1 ATOM 4595 C CB . TYR B 2 61 ? -19.438 -27.163 36.690 1.00 65.21 ? 61 TYR B CB 1 ATOM 4596 C CG . TYR B 2 61 ? -19.951 -25.820 37.207 1.00 65.64 ? 61 TYR B CG 1 ATOM 4597 C CD1 . TYR B 2 61 ? -20.981 -25.142 36.558 1.00 61.45 ? 61 TYR B CD1 1 ATOM 4598 C CD2 . TYR B 2 61 ? -19.354 -25.198 38.311 1.00 73.85 ? 61 TYR B CD2 1 ATOM 4599 C CE1 . TYR B 2 61 ? -21.436 -23.898 37.010 1.00 61.03 ? 61 TYR B CE1 1 ATOM 4600 C CE2 . TYR B 2 61 ? -19.800 -23.950 38.771 1.00 67.40 ? 61 TYR B CE2 1 ATOM 4601 C CZ . TYR B 2 61 ? -20.841 -23.308 38.111 1.00 69.03 ? 61 TYR B CZ 1 ATOM 4602 O OH . TYR B 2 61 ? -21.291 -22.078 38.552 1.00 73.20 ? 61 TYR B OH 1 ATOM 4603 O OXT . TYR B 2 61 ? -22.197 -28.109 35.686 1.00 77.50 ? 61 TYR B OXT 1 HETATM 4604 S S . SO4 C 3 . ? -47.960 -4.110 46.784 0.69 65.03 ? 601 SO4 A S 1 HETATM 4605 O O1 . SO4 C 3 . ? -46.602 -3.650 47.087 0.69 56.63 ? 601 SO4 A O1 1 HETATM 4606 O O2 . SO4 C 3 . ? -48.250 -3.961 45.345 0.69 69.87 ? 601 SO4 A O2 1 HETATM 4607 O O3 . SO4 C 3 . ? -48.077 -5.522 47.116 0.69 55.24 ? 601 SO4 A O3 1 HETATM 4608 O O4 . SO4 C 3 . ? -48.918 -3.348 47.578 0.69 50.37 ? 601 SO4 A O4 1 HETATM 4609 S S . SO4 D 3 . ? -52.840 -34.123 59.035 0.76 91.37 ? 602 SO4 A S 1 HETATM 4610 O O1 . SO4 D 3 . ? -52.014 -34.142 57.808 0.76 78.45 ? 602 SO4 A O1 1 HETATM 4611 O O2 . SO4 D 3 . ? -54.215 -33.784 58.675 0.76 97.56 ? 602 SO4 A O2 1 HETATM 4612 O O3 . SO4 D 3 . ? -52.809 -35.420 59.709 0.76 72.82 ? 602 SO4 A O3 1 HETATM 4613 O O4 . SO4 D 3 . ? -52.361 -33.139 60.000 0.76 78.26 ? 602 SO4 A O4 1 HETATM 4614 S S . SO4 E 3 . ? -53.805 1.678 63.837 0.85 91.40 ? 603 SO4 A S 1 HETATM 4615 O O1 . SO4 E 3 . ? -52.437 2.163 64.020 0.85 81.53 ? 603 SO4 A O1 1 HETATM 4616 O O2 . SO4 E 3 . ? -54.419 2.404 62.733 0.85 85.96 ? 603 SO4 A O2 1 HETATM 4617 O O3 . SO4 E 3 . ? -53.831 0.246 63.527 0.85 81.76 ? 603 SO4 A O3 1 HETATM 4618 O O4 . SO4 E 3 . ? -54.550 1.924 65.066 0.85 79.75 ? 603 SO4 A O4 1 HETATM 4619 S S . SO4 F 3 . ? -11.853 -32.027 89.084 0.83 110.06 ? 604 SO4 A S 1 HETATM 4620 O O1 . SO4 F 3 . ? -10.678 -32.267 88.245 0.83 99.05 ? 604 SO4 A O1 1 HETATM 4621 O O2 . SO4 F 3 . ? -12.840 -31.241 88.348 0.83 88.19 ? 604 SO4 A O2 1 HETATM 4622 O O3 . SO4 F 3 . ? -12.442 -33.311 89.464 0.83 105.89 ? 604 SO4 A O3 1 HETATM 4623 O O4 . SO4 F 3 . ? -11.454 -31.301 90.289 0.83 98.73 ? 604 SO4 A O4 1 HETATM 4624 C C1 . FUC G 4 . ? -27.107 -22.298 32.364 1.00 123.23 ? 605 FUC A C1 1 HETATM 4625 C C2 . FUC G 4 . ? -26.635 -23.699 31.952 1.00 132.03 ? 605 FUC A C2 1 HETATM 4626 C C3 . FUC G 4 . ? -26.069 -23.677 30.515 1.00 135.97 ? 605 FUC A C3 1 HETATM 4627 C C4 . FUC G 4 . ? -24.945 -22.610 30.385 1.00 136.29 ? 605 FUC A C4 1 HETATM 4628 C C5 . FUC G 4 . ? -25.449 -21.229 30.888 1.00 131.60 ? 605 FUC A C5 1 HETATM 4629 C C6 . FUC G 4 . ? -24.339 -20.187 30.978 1.00 122.63 ? 605 FUC A C6 1 HETATM 4630 O O2 . FUC G 4 . ? -27.687 -24.669 32.071 1.00 125.49 ? 605 FUC A O2 1 HETATM 4631 O O3 . FUC G 4 . ? -25.533 -24.951 30.165 1.00 135.75 ? 605 FUC A O3 1 HETATM 4632 O O4 . FUC G 4 . ? -23.807 -22.990 31.134 1.00 139.41 ? 605 FUC A O4 1 HETATM 4633 O O5 . FUC G 4 . ? -26.089 -21.313 32.203 1.00 121.42 ? 605 FUC A O5 1 HETATM 4634 C C1 . NAG H 5 . ? -28.956 -18.130 31.069 1.00 99.50 ? 606 NAG A C1 1 HETATM 4635 C C2 . NAG H 5 . ? -29.250 -18.408 29.592 1.00 103.68 ? 606 NAG A C2 1 HETATM 4636 C C3 . NAG H 5 . ? -30.340 -19.463 29.416 1.00 106.27 ? 606 NAG A C3 1 HETATM 4637 C C4 . NAG H 5 . ? -30.054 -20.707 30.266 1.00 112.42 ? 606 NAG A C4 1 HETATM 4638 C C5 . NAG H 5 . ? -29.682 -20.337 31.708 1.00 105.91 ? 606 NAG A C5 1 HETATM 4639 C C6 . NAG H 5 . ? -29.148 -21.567 32.438 1.00 107.06 ? 606 NAG A C6 1 HETATM 4640 C C7 . NAG H 5 . ? -28.708 -16.561 28.109 1.00 99.04 ? 606 NAG A C7 1 HETATM 4641 C C8 . NAG H 5 . ? -27.859 -17.416 27.217 1.00 93.55 ? 606 NAG A C8 1 HETATM 4642 N N2 . NAG H 5 . ? -29.599 -17.189 28.877 1.00 100.68 ? 606 NAG A N2 1 HETATM 4643 O O3 . NAG H 5 . ? -30.428 -19.785 28.045 1.00 108.99 ? 606 NAG A O3 1 HETATM 4644 O O4 . NAG H 5 . ? -31.169 -21.590 30.287 1.00 113.58 ? 606 NAG A O4 1 HETATM 4645 O O5 . NAG H 5 . ? -28.684 -19.335 31.758 1.00 104.13 ? 606 NAG A O5 1 HETATM 4646 O O6 . NAG H 5 . ? -28.071 -22.060 31.668 1.00 122.64 ? 606 NAG A O6 1 HETATM 4647 O O7 . NAG H 5 . ? -28.555 -15.339 28.120 1.00 98.85 ? 606 NAG A O7 1 HETATM 4648 C C1 . NAG I 5 . ? -30.825 -22.966 29.651 1.00 118.07 ? 607 NAG A C1 1 HETATM 4649 C C2 . NAG I 5 . ? -31.708 -24.094 30.219 1.00 118.62 ? 607 NAG A C2 1 HETATM 4650 C C3 . NAG I 5 . ? -31.567 -25.402 29.426 1.00 122.90 ? 607 NAG A C3 1 HETATM 4651 C C4 . NAG I 5 . ? -31.472 -25.202 27.910 1.00 127.72 ? 607 NAG A C4 1 HETATM 4652 C C5 . NAG I 5 . ? -30.503 -24.083 27.553 1.00 124.21 ? 607 NAG A C5 1 HETATM 4653 C C6 . NAG I 5 . ? -30.534 -23.839 26.047 1.00 119.33 ? 607 NAG A C6 1 HETATM 4654 C C7 . NAG I 5 . ? -32.383 -24.436 32.596 1.00 108.57 ? 607 NAG A C7 1 HETATM 4655 C C8 . NAG I 5 . ? -33.109 -25.744 32.750 1.00 102.55 ? 607 NAG A C8 1 HETATM 4656 N N2 . NAG I 5 . ? -31.442 -24.342 31.639 1.00 118.55 ? 607 NAG A N2 1 HETATM 4657 O O3 . NAG I 5 . ? -32.665 -26.247 29.701 1.00 127.59 ? 607 NAG A O3 1 HETATM 4658 O O4 . NAG I 5 . ? -31.040 -26.400 27.286 1.00 130.67 ? 607 NAG A O4 1 HETATM 4659 O O5 . NAG I 5 . ? -30.848 -22.895 28.236 1.00 124.92 ? 607 NAG A O5 1 HETATM 4660 O O6 . NAG I 5 . ? -29.881 -22.635 25.720 1.00 120.00 ? 607 NAG A O6 1 HETATM 4661 O O7 . NAG I 5 . ? -32.662 -23.513 33.361 1.00 93.74 ? 607 NAG A O7 1 HETATM 4662 C C1 . BMA J 6 . ? -32.137 -27.036 26.399 1.00 131.01 ? 608 BMA A C1 1 HETATM 4663 C C2 . BMA J 6 . ? -31.451 -27.782 25.259 1.00 130.92 ? 608 BMA A C2 1 HETATM 4664 C C3 . BMA J 6 . ? -32.458 -28.481 24.349 1.00 130.84 ? 608 BMA A C3 1 HETATM 4665 C C4 . BMA J 6 . ? -33.528 -29.220 25.150 1.00 136.34 ? 608 BMA A C4 1 HETATM 4666 C C5 . BMA J 6 . ? -34.092 -28.367 26.293 1.00 138.51 ? 608 BMA A C5 1 HETATM 4667 C C6 . BMA J 6 . ? -35.081 -29.171 27.150 1.00 130.52 ? 608 BMA A C6 1 HETATM 4668 O O2 . BMA J 6 . ? -30.540 -28.720 25.792 1.00 129.82 ? 608 BMA A O2 1 HETATM 4669 O O3 . BMA J 6 . ? -31.780 -29.398 23.514 1.00 128.46 ? 608 BMA A O3 1 HETATM 4670 O O4 . BMA J 6 . ? -34.569 -29.607 24.280 1.00 131.96 ? 608 BMA A O4 1 HETATM 4671 O O5 . BMA J 6 . ? -33.023 -27.892 27.094 1.00 139.42 ? 608 BMA A O5 1 HETATM 4672 O O6 . BMA J 6 . ? -35.579 -28.422 28.244 1.00 110.92 ? 608 BMA A O6 1 HETATM 4673 C C1 . NAG K 5 . ? -10.108 -8.056 49.370 1.00 124.42 ? 609 NAG A C1 1 HETATM 4674 C C2 . NAG K 5 . ? -10.050 -9.587 49.378 1.00 126.34 ? 609 NAG A C2 1 HETATM 4675 C C3 . NAG K 5 . ? -8.679 -10.093 48.926 1.00 130.77 ? 609 NAG A C3 1 HETATM 4676 C C4 . NAG K 5 . ? -8.309 -9.477 47.578 1.00 134.67 ? 609 NAG A C4 1 HETATM 4677 C C5 . NAG K 5 . ? -8.492 -7.956 47.588 1.00 130.75 ? 609 NAG A C5 1 HETATM 4678 C C6 . NAG K 5 . ? -8.305 -7.371 46.190 1.00 126.43 ? 609 NAG A C6 1 HETATM 4679 C C7 . NAG K 5 . ? -11.626 -10.587 50.939 1.00 117.39 ? 609 NAG A C7 1 HETATM 4680 C C8 . NAG K 5 . ? -12.396 -11.155 49.778 1.00 119.89 ? 609 NAG A C8 1 HETATM 4681 N N2 . NAG K 5 . ? -10.404 -10.111 50.687 1.00 122.34 ? 609 NAG A N2 1 HETATM 4682 O O3 . NAG K 5 . ? -8.673 -11.504 48.825 1.00 124.40 ? 609 NAG A O3 1 HETATM 4683 O O4 . NAG K 5 . ? -6.971 -9.802 47.260 1.00 129.73 ? 609 NAG A O4 1 HETATM 4684 O O5 . NAG K 5 . ? -9.772 -7.577 48.073 1.00 130.90 ? 609 NAG A O5 1 HETATM 4685 O O6 . NAG K 5 . ? -6.984 -7.602 45.757 1.00 125.10 ? 609 NAG A O6 1 HETATM 4686 O O7 . NAG K 5 . ? -12.129 -10.565 52.060 1.00 106.19 ? 609 NAG A O7 1 HETATM 4687 O O . HOH L 7 . ? -31.146 -37.496 65.954 1.00 47.81 ? 701 HOH A O 1 HETATM 4688 O O . HOH L 7 . ? -41.120 -33.608 59.593 1.00 46.34 ? 702 HOH A O 1 HETATM 4689 O O . HOH L 7 . ? -28.280 -37.819 65.651 1.00 51.02 ? 703 HOH A O 1 HETATM 4690 O O . HOH L 7 . ? -27.954 -22.364 88.291 1.00 50.66 ? 704 HOH A O 1 HETATM 4691 O O . HOH L 7 . ? -57.724 -19.694 66.559 1.00 53.32 ? 705 HOH A O 1 HETATM 4692 O O . HOH L 7 . ? -41.395 -34.548 56.713 0.97 52.48 ? 706 HOH A O 1 HETATM 4693 O O . HOH L 7 . ? -48.969 -40.557 62.175 1.00 67.52 ? 707 HOH A O 1 HETATM 4694 O O . HOH L 7 . ? -31.697 3.145 56.816 1.00 62.00 ? 708 HOH A O 1 HETATM 4695 O O . HOH L 7 . ? -58.315 -13.648 68.862 1.00 65.29 ? 709 HOH A O 1 HETATM 4696 O O . HOH L 7 . ? -27.564 -20.947 66.478 1.00 58.55 ? 710 HOH A O 1 HETATM 4697 O O . HOH L 7 . ? -25.943 -22.659 56.649 1.00 51.10 ? 711 HOH A O 1 HETATM 4698 O O . HOH L 7 . ? -32.025 -24.464 59.597 1.00 45.27 ? 712 HOH A O 1 HETATM 4699 O O . HOH L 7 . ? -32.740 -12.892 55.247 1.00 57.14 ? 713 HOH A O 1 HETATM 4700 O O . HOH L 7 . ? -52.723 -36.854 54.790 1.00 64.53 ? 714 HOH A O 1 HETATM 4701 O O . HOH L 7 . ? -33.721 -5.684 80.294 1.00 56.21 ? 715 HOH A O 1 HETATM 4702 O O . HOH L 7 . ? -48.118 1.398 62.227 1.00 62.39 ? 716 HOH A O 1 HETATM 4703 O O . HOH L 7 . ? -12.858 -22.102 66.421 1.00 54.44 ? 717 HOH A O 1 HETATM 4704 O O . HOH L 7 . ? -30.385 -6.649 82.241 1.00 57.16 ? 718 HOH A O 1 HETATM 4705 O O . HOH L 7 . ? -14.766 -11.954 80.162 1.00 62.34 ? 719 HOH A O 1 HETATM 4706 O O . HOH L 7 . ? -25.013 -27.739 63.297 1.00 50.54 ? 720 HOH A O 1 HETATM 4707 O O . HOH L 7 . ? -31.341 -37.786 72.199 1.00 53.37 ? 721 HOH A O 1 HETATM 4708 O O . HOH L 7 . ? -62.163 -26.066 52.914 1.00 71.36 ? 722 HOH A O 1 HETATM 4709 O O . HOH L 7 . ? -13.629 -21.493 86.981 1.00 60.87 ? 723 HOH A O 1 HETATM 4710 O O . HOH L 7 . ? -26.615 -43.221 65.346 1.00 61.95 ? 724 HOH A O 1 HETATM 4711 O O . HOH L 7 . ? -19.535 -17.562 64.556 1.00 62.93 ? 725 HOH A O 1 HETATM 4712 O O . HOH L 7 . ? -34.366 5.543 66.681 1.00 69.82 ? 726 HOH A O 1 HETATM 4713 O O . HOH L 7 . ? -29.410 -32.341 55.835 1.00 53.85 ? 727 HOH A O 1 HETATM 4714 O O . HOH L 7 . ? -40.764 -10.657 47.455 1.00 62.89 ? 728 HOH A O 1 HETATM 4715 O O . HOH L 7 . ? -8.668 -28.409 78.900 1.00 65.33 ? 729 HOH A O 1 HETATM 4716 O O . HOH L 7 . ? -42.420 -0.848 62.581 1.00 57.94 ? 730 HOH A O 1 HETATM 4717 O O . HOH L 7 . ? -17.783 -35.565 73.578 1.00 59.48 ? 731 HOH A O 1 HETATM 4718 O O . HOH L 7 . ? -50.000 -17.005 73.826 1.00 46.80 ? 732 HOH A O 1 HETATM 4719 O O . HOH L 7 . ? -22.613 -32.565 73.735 1.00 51.23 ? 733 HOH A O 1 HETATM 4720 O O . HOH L 7 . ? -35.075 -31.135 55.872 1.00 47.75 ? 734 HOH A O 1 HETATM 4721 O O . HOH L 7 . ? -20.066 -17.805 56.665 1.00 56.02 ? 735 HOH A O 1 HETATM 4722 O O . HOH L 7 . ? -32.724 -18.704 78.399 1.00 46.80 ? 736 HOH A O 1 HETATM 4723 O O . HOH L 7 . ? -55.245 -11.398 41.153 1.00 61.29 ? 737 HOH A O 1 HETATM 4724 O O . HOH L 7 . ? -21.922 -42.125 57.450 1.00 59.79 ? 738 HOH A O 1 HETATM 4725 O O . HOH L 7 . ? -32.991 -23.059 37.400 1.00 62.78 ? 739 HOH A O 1 HETATM 4726 O O . HOH L 7 . ? -22.450 -40.950 63.252 1.00 60.64 ? 740 HOH A O 1 HETATM 4727 O O . HOH L 7 . ? -15.823 -29.485 73.725 1.00 56.88 ? 741 HOH A O 1 HETATM 4728 O O . HOH L 7 . ? -55.095 -23.758 60.890 1.00 64.67 ? 742 HOH A O 1 HETATM 4729 O O . HOH M 7 . ? -14.985 -32.918 53.591 1.00 49.20 ? 101 HOH B O 1 HETATM 4730 O O . HOH M 7 . ? -14.599 -30.586 52.870 1.00 60.10 ? 102 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLY 1 2 ? ? ? A . n A 1 2 ARG 2 3 ? ? ? A . n A 1 3 GLU 3 4 ? ? ? A . n A 1 4 ASP 4 5 5 ASP ASP A . n A 1 5 ALA 5 6 6 ALA ALA A . n A 1 6 GLU 6 7 7 GLU GLU A . n A 1 7 LEU 7 8 8 LEU LEU A . n A 1 8 LEU 8 9 9 LEU LEU A . n A 1 9 VAL 9 10 10 VAL VAL A . n A 1 10 THR 10 11 11 THR THR A . n A 1 11 VAL 11 12 12 VAL VAL A . n A 1 12 ARG 12 13 13 ARG ARG A . n A 1 13 GLY 13 14 14 GLY GLY A . n A 1 14 GLY 14 15 15 GLY GLY A . n A 1 15 ARG 15 16 16 ARG ARG A . n A 1 16 LEU 16 17 17 LEU LEU A . n A 1 17 ARG 17 18 18 ARG ARG A . n A 1 18 GLY 18 19 19 GLY GLY A . n A 1 19 ILE 19 20 20 ILE ILE A . n A 1 20 ARG 20 21 21 ARG ARG A . n A 1 21 LEU 21 22 22 LEU LEU A . n A 1 22 LYS 22 23 23 LYS LYS A . n A 1 23 THR 23 24 24 THR THR A . n A 1 24 PRO 24 25 25 PRO PRO A . n A 1 25 GLY 25 26 26 GLY GLY A . n A 1 26 GLY 26 27 27 GLY GLY A . n A 1 27 PRO 27 28 28 PRO PRO A . n A 1 28 VAL 28 29 29 VAL VAL A . n A 1 29 SER 29 30 30 SER SER A . n A 1 30 ALA 30 31 31 ALA ALA A . n A 1 31 PHE 31 32 32 PHE PHE A . n A 1 32 LEU 32 33 33 LEU LEU A . n A 1 33 GLY 33 34 34 GLY GLY A . n A 1 34 ILE 34 35 35 ILE ILE A . n A 1 35 PRO 35 36 36 PRO PRO A . n A 1 36 PHE 36 37 37 PHE PHE A . n A 1 37 ALA 37 38 38 ALA ALA A . n A 1 38 GLU 38 39 39 GLU GLU A . n A 1 39 PRO 39 40 40 PRO PRO A . n A 1 40 PRO 40 41 41 PRO PRO A . n A 1 41 MET 41 42 42 MET MET A . n A 1 42 GLY 42 43 43 GLY GLY A . n A 1 43 PRO 43 44 44 PRO PRO A . n A 1 44 ARG 44 45 45 ARG ARG A . n A 1 45 ARG 45 46 46 ARG ARG A . n A 1 46 PHE 46 47 47 PHE PHE A . n A 1 47 LEU 47 48 48 LEU LEU A . n A 1 48 PRO 48 49 49 PRO PRO A . n A 1 49 PRO 49 50 50 PRO PRO A . n A 1 50 GLU 50 51 51 GLU GLU A . n A 1 51 PRO 51 52 52 PRO PRO A . n A 1 52 LYS 52 53 53 LYS LYS A . n A 1 53 GLN 53 54 54 GLN GLN A . n A 1 54 PRO 54 55 55 PRO PRO A . n A 1 55 TRP 55 56 56 TRP TRP A . n A 1 56 SER 56 57 57 SER SER A . n A 1 57 GLY 57 58 58 GLY GLY A . n A 1 58 VAL 58 59 59 VAL VAL A . n A 1 59 VAL 59 60 60 VAL VAL A . n A 1 60 ASP 60 61 61 ASP ASP A . n A 1 61 ALA 61 62 62 ALA ALA A . n A 1 62 THR 62 63 63 THR THR A . n A 1 63 THR 63 64 64 THR THR A . n A 1 64 PHE 64 65 65 PHE PHE A . n A 1 65 GLN 65 66 66 GLN GLN A . n A 1 66 SER 66 67 67 SER SER A . n A 1 67 VAL 67 68 68 VAL VAL A . n A 1 68 CYS 68 69 69 CYS CYS A . n A 1 69 TYR 69 70 70 TYR TYR A . n A 1 70 GLN 70 71 71 GLN GLN A . n A 1 71 TYR 71 72 72 TYR TYR A . n A 1 72 VAL 72 73 73 VAL VAL A . n A 1 73 ASP 73 74 74 ASP ASP A . n A 1 74 THR 74 75 75 THR THR A . n A 1 75 LEU 75 76 76 LEU LEU A . n A 1 76 TYR 76 77 77 TYR TYR A . n A 1 77 PRO 77 78 78 PRO PRO A . n A 1 78 GLY 78 79 79 GLY GLY A . n A 1 79 PHE 79 80 80 PHE PHE A . n A 1 80 GLU 80 81 81 GLU GLU A . n A 1 81 GLY 81 82 82 GLY GLY A . n A 1 82 THR 82 83 83 THR THR A . n A 1 83 GLU 83 84 84 GLU GLU A . n A 1 84 MET 84 85 85 MET MET A . n A 1 85 TRP 85 86 86 TRP TRP A . n A 1 86 ASN 86 87 87 ASN ASN A . n A 1 87 PRO 87 88 88 PRO PRO A . n A 1 88 ASN 88 89 89 ASN ASN A . n A 1 89 ARG 89 90 90 ARG ARG A . n A 1 90 GLU 90 91 91 GLU GLU A . n A 1 91 LEU 91 92 92 LEU LEU A . n A 1 92 SER 92 93 93 SER SER A . n A 1 93 GLU 93 94 94 GLU GLU A . n A 1 94 ASP 94 95 95 ASP ASP A . n A 1 95 CYS 95 96 96 CYS CYS A . n A 1 96 LEU 96 97 97 LEU LEU A . n A 1 97 TYR 97 98 98 TYR TYR A . n A 1 98 LEU 98 99 99 LEU LEU A . n A 1 99 ASN 99 100 100 ASN ASN A . n A 1 100 VAL 100 101 101 VAL VAL A . n A 1 101 TRP 101 102 102 TRP TRP A . n A 1 102 THR 102 103 103 THR THR A . n A 1 103 PRO 103 104 104 PRO PRO A . n A 1 104 TYR 104 105 105 TYR TYR A . n A 1 105 PRO 105 106 106 PRO PRO A . n A 1 106 ARG 106 107 107 ARG ARG A . n A 1 107 PRO 107 108 108 PRO PRO A . n A 1 108 THR 108 109 109 THR THR A . n A 1 109 SER 109 110 110 SER SER A . n A 1 110 PRO 110 111 111 PRO PRO A . n A 1 111 THR 111 112 112 THR THR A . n A 1 112 PRO 112 113 113 PRO PRO A . n A 1 113 VAL 113 114 114 VAL VAL A . n A 1 114 LEU 114 115 115 LEU LEU A . n A 1 115 VAL 115 116 116 VAL VAL A . n A 1 116 TRP 116 117 117 TRP TRP A . n A 1 117 ILE 117 118 118 ILE ILE A . n A 1 118 TYR 118 119 119 TYR TYR A . n A 1 119 GLY 119 120 120 GLY GLY A . n A 1 120 GLY 120 121 121 GLY GLY A . n A 1 121 GLY 121 122 122 GLY GLY A . n A 1 122 PHE 122 123 123 PHE PHE A . n A 1 123 TYR 123 124 124 TYR TYR A . n A 1 124 SER 124 125 125 SER SER A . n A 1 125 GLY 125 126 126 GLY GLY A . n A 1 126 ALA 126 127 127 ALA ALA A . n A 1 127 SER 127 128 128 SER SER A . n A 1 128 SER 128 129 129 SER SER A . n A 1 129 LEU 129 130 130 LEU LEU A . n A 1 130 ASP 130 131 131 ASP ASP A . n A 1 131 VAL 131 132 132 VAL VAL A . n A 1 132 TYR 132 133 133 TYR TYR A . n A 1 133 ASP 133 134 134 ASP ASP A . n A 1 134 GLY 134 135 135 GLY GLY A . n A 1 135 ARG 135 136 136 ARG ARG A . n A 1 136 PHE 136 137 137 PHE PHE A . n A 1 137 LEU 137 138 138 LEU LEU A . n A 1 138 VAL 138 139 139 VAL VAL A . n A 1 139 GLN 139 140 140 GLN GLN A . n A 1 140 ALA 140 141 141 ALA ALA A . n A 1 141 GLU 141 142 142 GLU GLU A . n A 1 142 ARG 142 143 143 ARG ARG A . n A 1 143 THR 143 144 144 THR THR A . n A 1 144 VAL 144 145 145 VAL VAL A . n A 1 145 LEU 145 146 146 LEU LEU A . n A 1 146 VAL 146 147 147 VAL VAL A . n A 1 147 SER 147 148 148 SER SER A . n A 1 148 MET 148 149 149 MET MET A . n A 1 149 ASN 149 150 150 ASN ASN A . n A 1 150 TYR 150 151 151 TYR TYR A . n A 1 151 ARG 151 152 152 ARG ARG A . n A 1 152 VAL 152 153 153 VAL VAL A . n A 1 153 GLY 153 154 154 GLY GLY A . n A 1 154 ALA 154 155 155 ALA ALA A . n A 1 155 PHE 155 156 156 PHE PHE A . n A 1 156 GLY 156 157 157 GLY GLY A . n A 1 157 PHE 157 158 158 PHE PHE A . n A 1 158 LEU 158 159 159 LEU LEU A . n A 1 159 ALA 159 160 160 ALA ALA A . n A 1 160 LEU 160 161 161 LEU LEU A . n A 1 161 PRO 161 162 162 PRO PRO A . n A 1 162 GLY 162 163 163 GLY GLY A . n A 1 163 SER 163 164 164 SER SER A . n A 1 164 ARG 164 165 165 ARG ARG A . n A 1 165 GLU 165 166 166 GLU GLU A . n A 1 166 ALA 166 167 167 ALA ALA A . n A 1 167 PRO 167 168 168 PRO PRO A . n A 1 168 GLY 168 169 169 GLY GLY A . n A 1 169 ASN 169 170 170 ASN ASN A . n A 1 170 VAL 170 171 171 VAL VAL A . n A 1 171 GLY 171 172 172 GLY GLY A . n A 1 172 LEU 172 173 173 LEU LEU A . n A 1 173 LEU 173 174 174 LEU LEU A . n A 1 174 ASP 174 175 175 ASP ASP A . n A 1 175 GLN 175 176 176 GLN GLN A . n A 1 176 ARG 176 177 177 ARG ARG A . n A 1 177 LEU 177 178 178 LEU LEU A . n A 1 178 ALA 178 179 179 ALA ALA A . n A 1 179 LEU 179 180 180 LEU LEU A . n A 1 180 GLN 180 181 181 GLN GLN A . n A 1 181 TRP 181 182 182 TRP TRP A . n A 1 182 VAL 182 183 183 VAL VAL A . n A 1 183 GLN 183 184 184 GLN GLN A . n A 1 184 GLU 184 185 185 GLU GLU A . n A 1 185 ASN 185 186 186 ASN ASN A . n A 1 186 VAL 186 187 187 VAL VAL A . n A 1 187 ALA 187 188 188 ALA ALA A . n A 1 188 ALA 188 189 189 ALA ALA A . n A 1 189 PHE 189 190 190 PHE PHE A . n A 1 190 GLY 190 191 191 GLY GLY A . n A 1 191 GLY 191 192 192 GLY GLY A . n A 1 192 ASP 192 193 193 ASP ASP A . n A 1 193 PRO 193 194 194 PRO PRO A . n A 1 194 THR 194 195 195 THR THR A . n A 1 195 SER 195 196 196 SER SER A . n A 1 196 VAL 196 197 197 VAL VAL A . n A 1 197 THR 197 198 198 THR THR A . n A 1 198 LEU 198 199 199 LEU LEU A . n A 1 199 PHE 199 200 200 PHE PHE A . n A 1 200 GLY 200 201 201 GLY GLY A . n A 1 201 GLU 201 202 202 GLU GLU A . n A 1 202 SER 202 203 203 SER SER A . n A 1 203 ALA 203 204 204 ALA ALA A . n A 1 204 GLY 204 205 205 GLY GLY A . n A 1 205 ALA 205 206 206 ALA ALA A . n A 1 206 ALA 206 207 207 ALA ALA A . n A 1 207 SER 207 208 208 SER SER A . n A 1 208 VAL 208 209 209 VAL VAL A . n A 1 209 GLY 209 210 210 GLY GLY A . n A 1 210 MET 210 211 211 MET MET A . n A 1 211 HIS 211 212 212 HIS HIS A . n A 1 212 LEU 212 213 213 LEU LEU A . n A 1 213 LEU 213 214 214 LEU LEU A . n A 1 214 SER 214 215 215 SER SER A . n A 1 215 PRO 215 216 216 PRO PRO A . n A 1 216 PRO 216 217 217 PRO PRO A . n A 1 217 SER 217 218 218 SER SER A . n A 1 218 ARG 218 219 219 ARG ARG A . n A 1 219 GLY 219 220 220 GLY GLY A . n A 1 220 LEU 220 221 221 LEU LEU A . n A 1 221 PHE 221 222 222 PHE PHE A . n A 1 222 HIS 222 223 223 HIS HIS A . n A 1 223 ARG 223 224 224 ARG ARG A . n A 1 224 ALA 224 225 225 ALA ALA A . n A 1 225 VAL 225 226 226 VAL VAL A . n A 1 226 LEU 226 227 227 LEU LEU A . n A 1 227 GLN 227 228 228 GLN GLN A . n A 1 228 SER 228 229 229 SER SER A . n A 1 229 GLY 229 230 230 GLY GLY A . n A 1 230 ALA 230 231 231 ALA ALA A . n A 1 231 PRO 231 232 232 PRO PRO A . n A 1 232 ASN 232 233 233 ASN ASN A . n A 1 233 GLY 233 234 234 GLY GLY A . n A 1 234 PRO 234 235 235 PRO PRO A . n A 1 235 TRP 235 236 236 TRP TRP A . n A 1 236 ALA 236 237 237 ALA ALA A . n A 1 237 THR 237 238 238 THR THR A . n A 1 238 VAL 238 239 239 VAL VAL A . n A 1 239 GLY 239 240 240 GLY GLY A . n A 1 240 MET 240 241 241 MET MET A . n A 1 241 GLY 241 242 242 GLY GLY A . n A 1 242 GLU 242 243 243 GLU GLU A . n A 1 243 ALA 243 244 244 ALA ALA A . n A 1 244 ARG 244 245 245 ARG ARG A . n A 1 245 ARG 245 246 246 ARG ARG A . n A 1 246 ARG 246 247 247 ARG ARG A . n A 1 247 ALA 247 248 248 ALA ALA A . n A 1 248 THR 248 249 249 THR THR A . n A 1 249 GLN 249 250 250 GLN GLN A . n A 1 250 LEU 250 251 251 LEU LEU A . n A 1 251 ALA 251 252 252 ALA ALA A . n A 1 252 HIS 252 253 253 HIS HIS A . n A 1 253 LEU 253 254 254 LEU LEU A . n A 1 254 VAL 254 255 255 VAL VAL A . n A 1 255 GLY 255 256 256 GLY GLY A . n A 1 256 CYS 256 257 257 CYS CYS A . n A 1 257 PRO 257 258 258 PRO PRO A . n A 1 258 PRO 258 259 ? ? ? A . n A 1 259 GLY 259 260 ? ? ? A . n A 1 260 GLY 260 261 ? ? ? A . n A 1 261 THR 261 262 ? ? ? A . n A 1 262 GLY 262 263 ? ? ? A . n A 1 263 GLY 263 264 ? ? ? A . n A 1 264 ASN 264 265 265 ASN ASN A . n A 1 265 ASP 265 266 266 ASP ASP A . n A 1 266 THR 266 267 267 THR THR A . n A 1 267 GLU 267 268 268 GLU GLU A . n A 1 268 LEU 268 269 269 LEU LEU A . n A 1 269 VAL 269 270 270 VAL VAL A . n A 1 270 ALA 270 271 271 ALA ALA A . n A 1 271 CYS 271 272 272 CYS CYS A . n A 1 272 LEU 272 273 273 LEU LEU A . n A 1 273 ARG 273 274 274 ARG ARG A . n A 1 274 THR 274 275 275 THR THR A . n A 1 275 ARG 275 276 276 ARG ARG A . n A 1 276 PRO 276 277 277 PRO PRO A . n A 1 277 ALA 277 278 278 ALA ALA A . n A 1 278 GLN 278 279 279 GLN GLN A . n A 1 279 VAL 279 280 280 VAL VAL A . n A 1 280 LEU 280 281 281 LEU LEU A . n A 1 281 VAL 281 282 282 VAL VAL A . n A 1 282 ASN 282 283 283 ASN ASN A . n A 1 283 HIS 283 284 284 HIS HIS A . n A 1 284 GLU 284 285 285 GLU GLU A . n A 1 285 TRP 285 286 286 TRP TRP A . n A 1 286 HIS 286 287 287 HIS HIS A . n A 1 287 VAL 287 288 288 VAL VAL A . n A 1 288 LEU 288 289 289 LEU LEU A . n A 1 289 PRO 289 290 290 PRO PRO A . n A 1 290 GLN 290 291 291 GLN GLN A . n A 1 291 GLU 291 292 292 GLU GLU A . n A 1 292 SER 292 293 293 SER SER A . n A 1 293 VAL 293 294 294 VAL VAL A . n A 1 294 PHE 294 295 295 PHE PHE A . n A 1 295 ARG 295 296 296 ARG ARG A . n A 1 296 PHE 296 297 297 PHE PHE A . n A 1 297 SER 297 298 298 SER SER A . n A 1 298 PHE 298 299 299 PHE PHE A . n A 1 299 VAL 299 300 300 VAL VAL A . n A 1 300 PRO 300 301 301 PRO PRO A . n A 1 301 VAL 301 302 302 VAL VAL A . n A 1 302 VAL 302 303 303 VAL VAL A . n A 1 303 ASP 303 304 304 ASP ASP A . n A 1 304 GLY 304 305 305 GLY GLY A . n A 1 305 ASP 305 306 306 ASP ASP A . n A 1 306 PHE 306 307 307 PHE PHE A . n A 1 307 LEU 307 308 308 LEU LEU A . n A 1 308 SER 308 309 309 SER SER A . n A 1 309 ASP 309 310 310 ASP ASP A . n A 1 310 THR 310 311 311 THR THR A . n A 1 311 PRO 311 312 312 PRO PRO A . n A 1 312 GLU 312 313 313 GLU GLU A . n A 1 313 ALA 313 314 314 ALA ALA A . n A 1 314 LEU 314 315 315 LEU LEU A . n A 1 315 ILE 315 316 316 ILE ILE A . n A 1 316 ASN 316 317 317 ASN ASN A . n A 1 317 ALA 317 318 318 ALA ALA A . n A 1 318 GLY 318 319 319 GLY GLY A . n A 1 319 ASP 319 320 320 ASP ASP A . n A 1 320 PHE 320 321 321 PHE PHE A . n A 1 321 HIS 321 322 322 HIS HIS A . n A 1 322 GLY 322 323 323 GLY GLY A . n A 1 323 LEU 323 324 324 LEU LEU A . n A 1 324 GLN 324 325 325 GLN GLN A . n A 1 325 VAL 325 326 326 VAL VAL A . n A 1 326 LEU 326 327 327 LEU LEU A . n A 1 327 VAL 327 328 328 VAL VAL A . n A 1 328 GLY 328 329 329 GLY GLY A . n A 1 329 VAL 329 330 330 VAL VAL A . n A 1 330 VAL 330 331 331 VAL VAL A . n A 1 331 LYS 331 332 332 LYS LYS A . n A 1 332 ASP 332 333 333 ASP ASP A . n A 1 333 GLU 333 334 334 GLU GLU A . n A 1 334 GLY 334 335 335 GLY GLY A . n A 1 335 SER 335 336 336 SER SER A . n A 1 336 TYR 336 337 337 TYR TYR A . n A 1 337 PHE 337 338 338 PHE PHE A . n A 1 338 LEU 338 339 339 LEU LEU A . n A 1 339 VAL 339 340 340 VAL VAL A . n A 1 340 TYR 340 341 341 TYR TYR A . n A 1 341 GLY 341 342 342 GLY GLY A . n A 1 342 ALA 342 343 343 ALA ALA A . n A 1 343 PRO 343 344 344 PRO PRO A . n A 1 344 GLY 344 345 345 GLY GLY A . n A 1 345 PHE 345 346 346 PHE PHE A . n A 1 346 SER 346 347 347 SER SER A . n A 1 347 LYS 347 348 348 LYS LYS A . n A 1 348 ASP 348 349 349 ASP ASP A . n A 1 349 ASN 349 350 350 ASN ASN A . n A 1 350 GLU 350 351 351 GLU GLU A . n A 1 351 SER 351 352 352 SER SER A . n A 1 352 LEU 352 353 353 LEU LEU A . n A 1 353 ILE 353 354 354 ILE ILE A . n A 1 354 SER 354 355 355 SER SER A . n A 1 355 ARG 355 356 356 ARG ARG A . n A 1 356 ALA 356 357 357 ALA ALA A . n A 1 357 GLU 357 358 358 GLU GLU A . n A 1 358 PHE 358 359 359 PHE PHE A . n A 1 359 LEU 359 360 360 LEU LEU A . n A 1 360 ALA 360 361 361 ALA ALA A . n A 1 361 GLY 361 362 362 GLY GLY A . n A 1 362 VAL 362 363 363 VAL VAL A . n A 1 363 ARG 363 364 364 ARG ARG A . n A 1 364 VAL 364 365 365 VAL VAL A . n A 1 365 GLY 365 366 366 GLY GLY A . n A 1 366 VAL 366 367 367 VAL VAL A . n A 1 367 PRO 367 368 368 PRO PRO A . n A 1 368 GLN 368 369 369 GLN GLN A . n A 1 369 VAL 369 370 370 VAL VAL A . n A 1 370 SER 370 371 371 SER SER A . n A 1 371 ASP 371 372 372 ASP ASP A . n A 1 372 LEU 372 373 373 LEU LEU A . n A 1 373 ALA 373 374 374 ALA ALA A . n A 1 374 ALA 374 375 375 ALA ALA A . n A 1 375 GLU 375 376 376 GLU GLU A . n A 1 376 ALA 376 377 377 ALA ALA A . n A 1 377 VAL 377 378 378 VAL VAL A . n A 1 378 VAL 378 379 379 VAL VAL A . n A 1 379 LEU 379 380 380 LEU LEU A . n A 1 380 HIS 380 381 381 HIS HIS A . n A 1 381 TYR 381 382 382 TYR TYR A . n A 1 382 THR 382 383 383 THR THR A . n A 1 383 ASP 383 384 384 ASP ASP A . n A 1 384 TRP 384 385 385 TRP TRP A . n A 1 385 LEU 385 386 386 LEU LEU A . n A 1 386 HIS 386 387 387 HIS HIS A . n A 1 387 PRO 387 388 388 PRO PRO A . n A 1 388 GLU 388 389 389 GLU GLU A . n A 1 389 ASP 389 390 390 ASP ASP A . n A 1 390 PRO 390 391 391 PRO PRO A . n A 1 391 ALA 391 392 392 ALA ALA A . n A 1 392 ARG 392 393 393 ARG ARG A . n A 1 393 LEU 393 394 394 LEU LEU A . n A 1 394 ARG 394 395 395 ARG ARG A . n A 1 395 GLU 395 396 396 GLU GLU A . n A 1 396 ALA 396 397 397 ALA ALA A . n A 1 397 LEU 397 398 398 LEU LEU A . n A 1 398 SER 398 399 399 SER SER A . n A 1 399 ASP 399 400 400 ASP ASP A . n A 1 400 VAL 400 401 401 VAL VAL A . n A 1 401 VAL 401 402 402 VAL VAL A . n A 1 402 GLY 402 403 403 GLY GLY A . n A 1 403 ASP 403 404 404 ASP ASP A . n A 1 404 HIS 404 405 405 HIS HIS A . n A 1 405 ASN 405 406 406 ASN ASN A . n A 1 406 VAL 406 407 407 VAL VAL A . n A 1 407 VAL 407 408 408 VAL VAL A . n A 1 408 CYS 408 409 409 CYS CYS A . n A 1 409 PRO 409 410 410 PRO PRO A . n A 1 410 VAL 410 411 411 VAL VAL A . n A 1 411 ALA 411 412 412 ALA ALA A . n A 1 412 GLN 412 413 413 GLN GLN A . n A 1 413 LEU 413 414 414 LEU LEU A . n A 1 414 ALA 414 415 415 ALA ALA A . n A 1 415 GLY 415 416 416 GLY GLY A . n A 1 416 ARG 416 417 417 ARG ARG A . n A 1 417 LEU 417 418 418 LEU LEU A . n A 1 418 ALA 418 419 419 ALA ALA A . n A 1 419 ALA 419 420 420 ALA ALA A . n A 1 420 GLN 420 421 421 GLN GLN A . n A 1 421 GLY 421 422 422 GLY GLY A . n A 1 422 ALA 422 423 423 ALA ALA A . n A 1 423 ARG 423 424 424 ARG ARG A . n A 1 424 VAL 424 425 425 VAL VAL A . n A 1 425 TYR 425 426 426 TYR TYR A . n A 1 426 ALA 426 427 427 ALA ALA A . n A 1 427 TYR 427 428 428 TYR TYR A . n A 1 428 VAL 428 429 429 VAL VAL A . n A 1 429 PHE 429 430 430 PHE PHE A . n A 1 430 GLU 430 431 431 GLU GLU A . n A 1 431 HIS 431 432 432 HIS HIS A . n A 1 432 ARG 432 433 433 ARG ARG A . n A 1 433 ALA 433 434 434 ALA ALA A . n A 1 434 SER 434 435 435 SER SER A . n A 1 435 THR 435 436 436 THR THR A . n A 1 436 LEU 436 437 437 LEU LEU A . n A 1 437 SER 437 438 438 SER SER A . n A 1 438 TRP 438 439 439 TRP TRP A . n A 1 439 PRO 439 440 440 PRO PRO A . n A 1 440 LEU 440 441 441 LEU LEU A . n A 1 441 TRP 441 442 442 TRP TRP A . n A 1 442 MET 442 443 443 MET MET A . n A 1 443 GLY 443 444 444 GLY GLY A . n A 1 444 VAL 444 445 445 VAL VAL A . n A 1 445 PRO 445 446 446 PRO PRO A . n A 1 446 HIS 446 447 447 HIS HIS A . n A 1 447 GLY 447 448 448 GLY GLY A . n A 1 448 TYR 448 449 449 TYR TYR A . n A 1 449 GLU 449 450 450 GLU GLU A . n A 1 450 ILE 450 451 451 ILE ILE A . n A 1 451 GLU 451 452 452 GLU GLU A . n A 1 452 PHE 452 453 453 PHE PHE A . n A 1 453 ILE 453 454 454 ILE ILE A . n A 1 454 PHE 454 455 455 PHE PHE A . n A 1 455 GLY 455 456 456 GLY GLY A . n A 1 456 ILE 456 457 457 ILE ILE A . n A 1 457 PRO 457 458 458 PRO PRO A . n A 1 458 LEU 458 459 459 LEU LEU A . n A 1 459 ASP 459 460 460 ASP ASP A . n A 1 460 PRO 460 461 461 PRO PRO A . n A 1 461 SER 461 462 462 SER SER A . n A 1 462 ARG 462 463 463 ARG ARG A . n A 1 463 ASN 463 464 464 ASN ASN A . n A 1 464 TYR 464 465 465 TYR TYR A . n A 1 465 THR 465 466 466 THR THR A . n A 1 466 ALA 466 467 467 ALA ALA A . n A 1 467 GLU 467 468 468 GLU GLU A . n A 1 468 GLU 468 469 469 GLU GLU A . n A 1 469 LYS 469 470 470 LYS LYS A . n A 1 470 ILE 470 471 471 ILE ILE A . n A 1 471 PHE 471 472 472 PHE PHE A . n A 1 472 ALA 472 473 473 ALA ALA A . n A 1 473 GLN 473 474 474 GLN GLN A . n A 1 474 ARG 474 475 475 ARG ARG A . n A 1 475 LEU 475 476 476 LEU LEU A . n A 1 476 MET 476 477 477 MET MET A . n A 1 477 ARG 477 478 478 ARG ARG A . n A 1 478 TYR 478 479 479 TYR TYR A . n A 1 479 TRP 479 480 480 TRP TRP A . n A 1 480 ALA 480 481 481 ALA ALA A . n A 1 481 ASN 481 482 482 ASN ASN A . n A 1 482 PHE 482 483 483 PHE PHE A . n A 1 483 ALA 483 484 484 ALA ALA A . n A 1 484 ARG 484 485 485 ARG ARG A . n A 1 485 THR 485 486 486 THR THR A . n A 1 486 GLY 486 487 487 GLY GLY A . n A 1 487 ASP 487 488 488 ASP ASP A . n A 1 488 PRO 488 489 489 PRO PRO A . n A 1 489 ASN 489 490 490 ASN ASN A . n A 1 490 GLU 490 491 491 GLU GLU A . n A 1 491 PRO 491 492 492 PRO PRO A . n A 1 492 ARG 492 493 493 ARG ARG A . n A 1 493 ASP 493 494 494 ASP ASP A . n A 1 494 PRO 494 495 ? ? ? A . n A 1 495 LYS 495 496 ? ? ? A . n A 1 496 ALA 496 497 ? ? ? A . n A 1 497 PRO 497 498 498 PRO PRO A . n A 1 498 GLN 498 499 499 GLN GLN A . n A 1 499 TRP 499 500 500 TRP TRP A . n A 1 500 PRO 500 501 501 PRO PRO A . n A 1 501 PRO 501 502 502 PRO PRO A . n A 1 502 TYR 502 503 503 TYR TYR A . n A 1 503 THR 503 504 504 THR THR A . n A 1 504 ALA 504 505 505 ALA ALA A . n A 1 505 GLY 505 506 506 GLY GLY A . n A 1 506 ALA 506 507 507 ALA ALA A . n A 1 507 GLN 507 508 508 GLN GLN A . n A 1 508 GLN 508 509 509 GLN GLN A . n A 1 509 TYR 509 510 510 TYR TYR A . n A 1 510 VAL 510 511 511 VAL VAL A . n A 1 511 SER 511 512 512 SER SER A . n A 1 512 LEU 512 513 513 LEU LEU A . n A 1 513 ASP 513 514 514 ASP ASP A . n A 1 514 LEU 514 515 515 LEU LEU A . n A 1 515 ARG 515 516 516 ARG ARG A . n A 1 516 PRO 516 517 517 PRO PRO A . n A 1 517 LEU 517 518 518 LEU LEU A . n A 1 518 GLU 518 519 519 GLU GLU A . n A 1 519 VAL 519 520 520 VAL VAL A . n A 1 520 ARG 520 521 521 ARG ARG A . n A 1 521 ARG 521 522 522 ARG ARG A . n A 1 522 GLY 522 523 523 GLY GLY A . n A 1 523 LEU 523 524 524 LEU LEU A . n A 1 524 ARG 524 525 525 ARG ARG A . n A 1 525 ALA 525 526 526 ALA ALA A . n A 1 526 GLN 526 527 527 GLN GLN A . n A 1 527 ALA 527 528 528 ALA ALA A . n A 1 528 CYS 528 529 529 CYS CYS A . n A 1 529 ALA 529 530 530 ALA ALA A . n A 1 530 PHE 530 531 531 PHE PHE A . n A 1 531 TRP 531 532 532 TRP TRP A . n A 1 532 ASN 532 533 533 ASN ASN A . n A 1 533 ARG 533 534 534 ARG ARG A . n A 1 534 PHE 534 535 535 PHE PHE A . n A 1 535 LEU 535 536 536 LEU LEU A . n A 1 536 PRO 536 537 537 PRO PRO A . n A 1 537 LYS 537 538 538 LYS LYS A . n A 1 538 LEU 538 539 539 LEU LEU A . n A 1 539 LEU 539 540 540 LEU LEU A . n A 1 540 SER 540 541 541 SER SER A . n A 1 541 ALA 541 542 542 ALA ALA A . n A 1 542 THR 542 543 543 THR THR A . n B 2 1 THR 1 1 1 THR THR B . n B 2 2 MET 2 2 2 MET MET B . n B 2 3 CYS 3 3 3 CYS CYS B . n B 2 4 TYR 4 4 4 TYR TYR B . n B 2 5 SER 5 5 5 SER SER B . n B 2 6 HIS 6 6 6 HIS HIS B . n B 2 7 THR 7 7 7 THR THR B . n B 2 8 THR 8 8 8 THR THR B . n B 2 9 THR 9 9 9 THR THR B . n B 2 10 SER 10 10 10 SER SER B . n B 2 11 ARG 11 11 11 ARG ARG B . n B 2 12 ALA 12 12 12 ALA ALA B . n B 2 13 ILE 13 13 13 ILE ILE B . n B 2 14 LEU 14 14 14 LEU LEU B . n B 2 15 THR 15 15 15 THR THR B . n B 2 16 ASN 16 16 16 ASN ASN B . n B 2 17 CYS 17 17 17 CYS CYS B . n B 2 18 GLY 18 18 18 GLY GLY B . n B 2 19 GLU 19 19 19 GLU GLU B . n B 2 20 ASN 20 20 20 ASN ASN B . n B 2 21 SER 21 21 21 SER SER B . n B 2 22 CYS 22 22 22 CYS CYS B . n B 2 23 TYR 23 23 23 TYR TYR B . n B 2 24 ARG 24 24 24 ARG ARG B . n B 2 25 LYS 25 25 25 LYS LYS B . n B 2 26 SER 26 26 26 SER SER B . n B 2 27 ARG 27 27 27 ARG ARG B . n B 2 28 ARG 28 28 28 ARG ARG B . n B 2 29 HIS 29 29 29 HIS HIS B . n B 2 30 PRO 30 30 30 PRO PRO B . n B 2 31 PRO 31 31 31 PRO PRO B . n B 2 32 LYS 32 32 32 LYS LYS B . n B 2 33 MET 33 33 33 MET MET B . n B 2 34 VAL 34 34 34 VAL VAL B . n B 2 35 LEU 35 35 35 LEU LEU B . n B 2 36 GLY 36 36 36 GLY GLY B . n B 2 37 ARG 37 37 37 ARG ARG B . n B 2 38 GLY 38 38 38 GLY GLY B . n B 2 39 CYS 39 39 39 CYS CYS B . n B 2 40 GLY 40 40 40 GLY GLY B . n B 2 41 CYS 41 41 41 CYS CYS B . n B 2 42 PRO 42 42 42 PRO PRO B . n B 2 43 PRO 43 43 43 PRO PRO B . n B 2 44 GLY 44 44 44 GLY GLY B . n B 2 45 ASP 45 45 45 ASP ASP B . n B 2 46 ASP 46 46 46 ASP ASP B . n B 2 47 ASN 47 47 47 ASN ASN B . n B 2 48 LEU 48 48 48 LEU LEU B . n B 2 49 GLU 49 49 49 GLU GLU B . n B 2 50 VAL 50 50 50 VAL VAL B . n B 2 51 LYS 51 51 51 LYS LYS B . n B 2 52 CYS 52 52 52 CYS CYS B . n B 2 53 CYS 53 53 53 CYS CYS B . n B 2 54 THR 54 54 54 THR THR B . n B 2 55 SER 55 55 55 SER SER B . n B 2 56 PRO 56 56 56 PRO PRO B . n B 2 57 ASP 57 57 57 ASP ASP B . n B 2 58 LYS 58 58 58 LYS LYS B . n B 2 59 CYS 59 59 59 CYS CYS B . n B 2 60 ASN 60 60 60 ASN ASN B . n B 2 61 TYR 61 61 61 TYR TYR B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 3 SO4 1 601 1 SO4 SO4 A . D 3 SO4 1 602 2 SO4 SO4 A . E 3 SO4 1 603 3 SO4 SO4 A . F 3 SO4 1 604 4 SO4 SO4 A . G 4 FUC 1 605 1 FUC FUC A . H 5 NAG 2 606 2 NAG NAG A . I 5 NAG 3 607 3 NAG NAG A . J 6 BMA 4 608 4 BMA BMA A . K 5 NAG 1 609 5 NAG NAG A . L 7 HOH 1 701 1 HOH HOH A . L 7 HOH 2 702 2 HOH HOH A . L 7 HOH 3 703 3 HOH HOH A . L 7 HOH 4 704 4 HOH HOH A . L 7 HOH 5 705 5 HOH HOH A . L 7 HOH 6 706 6 HOH HOH A . L 7 HOH 7 707 7 HOH HOH A . L 7 HOH 8 708 8 HOH HOH A . L 7 HOH 9 709 9 HOH HOH A . L 7 HOH 10 710 10 HOH HOH A . L 7 HOH 11 711 11 HOH HOH A . L 7 HOH 12 712 12 HOH HOH A . L 7 HOH 13 713 13 HOH HOH A . L 7 HOH 14 714 14 HOH HOH A . L 7 HOH 15 715 15 HOH HOH A . L 7 HOH 16 716 16 HOH HOH A . L 7 HOH 17 717 17 HOH HOH A . L 7 HOH 18 718 19 HOH HOH A . L 7 HOH 19 719 20 HOH HOH A . L 7 HOH 20 720 21 HOH HOH A . L 7 HOH 21 721 23 HOH HOH A . L 7 HOH 22 722 24 HOH HOH A . L 7 HOH 23 723 25 HOH HOH A . L 7 HOH 24 724 26 HOH HOH A . L 7 HOH 25 725 27 HOH HOH A . L 7 HOH 26 726 28 HOH HOH A . L 7 HOH 27 727 29 HOH HOH A . L 7 HOH 28 728 30 HOH HOH A . L 7 HOH 29 729 31 HOH HOH A . L 7 HOH 30 730 32 HOH HOH A . L 7 HOH 31 731 33 HOH HOH A . L 7 HOH 32 732 34 HOH HOH A . L 7 HOH 33 733 35 HOH HOH A . L 7 HOH 34 734 36 HOH HOH A . L 7 HOH 35 735 37 HOH HOH A . L 7 HOH 36 736 38 HOH HOH A . L 7 HOH 37 737 39 HOH HOH A . L 7 HOH 38 738 40 HOH HOH A . L 7 HOH 39 739 41 HOH HOH A . L 7 HOH 40 740 42 HOH HOH A . L 7 HOH 41 741 43 HOH HOH A . L 7 HOH 42 742 44 HOH HOH A . M 7 HOH 1 101 18 HOH HOH B . M 7 HOH 2 102 22 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 463 A ASN 464 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 349 A ASN 350 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 2180 ? 1 MORE -8 ? 1 'SSA (A^2)' 22300 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2012-10-17 2 'Structure model' 1 1 2012-12-12 3 'Structure model' 1 2 2017-11-15 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 3 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # _phasing.method MR # loop_ _software.pdbx_ordinal _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id 1 DENZO . ? package 'Zbyszek Otwinowski' hkl@hkl-xray.com 'data reduction' http://www.hkl-xray.com/ ? ? 2 SCALEPACK . ? package 'Zbyszek Otwinowski' hkl@hkl-xray.com 'data scaling' http://www.hkl-xray.com/ ? ? 3 PHASER . ? program 'Randy J. Read' cimr-phaser@lists.cam.ac.uk phasing http://www-structmed.cimr.cam.ac.uk/phaser/ ? ? 4 PHENIX 1.8_1069 ? package 'Paul D. Adams' PDAdams@lbl.gov refinement http://www.phenix-online.org/ C++ ? 5 PDB_EXTRACT 3.11 'April 22, 2011' package PDB deposit@deposit.rcsb.org 'data extraction' http://sw-tools.pdb.org/apps/PDB_EXTRACT/ C++ ? 6 HKL-2000 . ? ? ? ? 'data collection' ? ? ? 7 HKL-2000 . ? ? ? ? 'data reduction' ? ? ? 8 HKL-2000 . ? ? ? ? 'data scaling' ? ? ? # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 C1 A FUC 605 ? ? C6 A NAG 606 ? ? 2.17 2 1 O5 A FUC 605 ? ? O6 A NAG 606 ? ? 2.18 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 PRO A 25 ? ? -37.53 -28.36 2 1 PHE A 47 ? ? 77.40 -16.67 3 1 ALA A 62 ? ? -109.88 44.16 4 1 PHE A 123 ? ? 57.12 3.27 5 1 SER A 203 ? ? 60.58 -120.46 6 1 PRO A 217 ? ? -54.95 -9.10 7 1 PRO A 290 ? ? -56.90 -71.02 8 1 ASP A 306 ? ? -93.87 -85.77 9 1 VAL A 407 ? ? -131.59 -61.74 10 1 ASN A 464 ? ? -97.86 46.43 11 1 ASP A 488 ? ? -160.05 116.11 12 1 ARG A 493 ? ? -125.51 -150.56 13 1 SER A 541 ? ? -69.73 1.83 14 1 HIS B 6 ? ? 172.16 158.52 15 1 THR B 7 ? ? -100.38 -162.28 16 1 ASP B 45 ? ? -165.12 -167.87 17 1 PRO B 56 ? ? -83.41 -145.67 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLY 2 ? A GLY 1 2 1 Y 1 A ARG 3 ? A ARG 2 3 1 Y 1 A GLU 4 ? A GLU 3 4 1 Y 1 A PRO 259 ? A PRO 258 5 1 Y 1 A GLY 260 ? A GLY 259 6 1 Y 1 A GLY 261 ? A GLY 260 7 1 Y 1 A THR 262 ? A THR 261 8 1 Y 1 A GLY 263 ? A GLY 262 9 1 Y 1 A GLY 264 ? A GLY 263 10 1 Y 1 A PRO 495 ? A PRO 494 11 1 Y 1 A LYS 496 ? A LYS 495 12 1 Y 1 A ALA 497 ? A ALA 496 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 3 'SULFATE ION' SO4 4 ALPHA-L-FUCOSE FUC 5 N-ACETYL-D-GLUCOSAMINE NAG 6 BETA-D-MANNOSE BMA 7 water HOH #