data_3WLO # _entry.id 3WLO # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.281 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3WLO RCSB RCSB096491 WWPDB D_1000096491 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1EX1 . unspecified PDB 1IEQ . unspecified PDB 1IEV . unspecified PDB 1IEW . unspecified PDB 1IEX . unspecified PDB 1J8V . unspecified PDB 3WLH . unspecified PDB 3WLI . unspecified PDB 3WLJ . unspecified PDB 3WLK . unspecified PDB 3WLL . unspecified PDB 3WLM . unspecified PDB 3WLN . unspecified PDB 3WLP . unspecified PDB 3WLQ . unspecified PDB 3WLR . unspecified PDB 3WLS . unspecified PDB 3WLT . unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 3WLO _pdbx_database_status.recvd_initial_deposition_date 2013-11-12 _pdbx_database_status.deposit_site PDBJ _pdbx_database_status.process_site PDBJ _pdbx_database_status.methods_development_category ? _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Streltsov, V.A.' 1 'Luang, S.' 2 'Hrmova, M.' 3 # _citation.id primary _citation.title 'A landscape of the product and substrate trajectories in a glycoside hydrolase' _citation.journal_abbrev 'To be Published' _citation.journal_volume ? _citation.page_first ? _citation.page_last ? _citation.year ? _citation.journal_id_ASTM ? _citation.country ? _citation.journal_id_ISSN ? _citation.journal_id_CSD 0353 _citation.book_publisher ? _citation.pdbx_database_id_PubMed ? _citation.pdbx_database_id_DOI ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Streltsov, V.A.' 1 primary 'Luang, S.' 2 primary 'Ketudat-Cairns, J.R.' 3 primary 'Raab, M.' 4 primary 'Tvaroska, I.' 5 primary 'Fort, S.' 6 primary 'Jimenez-Barbero, J.' 7 primary 'Peisley, A.' 8 primary 'Varghese, J.N.' 9 primary 'Hrmova, M.' 10 # _cell.entry_id 3WLO _cell.length_a 100.162 _cell.length_b 100.162 _cell.length_c 183.012 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 3WLO _symmetry.space_group_name_H-M 'P 43 21 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 96 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Beta-D-glucan exohydrolase isoenzyme ExoI' 65894.070 1 3.2.1.- ? 'UNP RESIDUES 26-630' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 3 ? ? ? ? 3 non-polymer man BETA-D-GLUCOSE 180.156 2 ? ? ? ? 4 non-polymer syn 'SULFATE ION' 96.063 1 ? ? ? ? 5 water nat water 18.015 1025 ? ? ? ? # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;HHAADYVLYKDATKPVEDRVADLLGRMTLAEKIGQMTQIERLVATPDVLRDNFIGSLLSGGGSVPRKGATAKEWQDMVDG FQKACMSTRLGIPMIYGIDAVHGQNNVYGATIFPHNVGLGATRDPYLVKRIGEATALEVRATGIQYAFAPCIAVCRDPRW GRCYESYSEDRRIVQSMTELIPGLQGDVPKDFTSGMPFVAGKNKVAACAKHFVGDGGTVDGINENNTIINREGLMNIHMP AYKNAMDKGVSTVMISYSSWNGVKMHANQDLVTGYLKDTLKFKGFVISDWEGIDRITTPAGSDYSYSVKASILAGLDMIM VPNKYQQFISILTGHVNGGVIPMSRIDDAVTRILRVKFTMGLFENPYADPAMAEQLGKQEHRDLAREAARKSLVLLKNGK TSTDAPLLPLPKKAPKILVAGSHADNLGYQCGGWTIEWQGDTGRTTVGTTILEAVKAAVDPSTVVVFAENPDAEFVKSGG FSYAIVAVGEHPYTETKGDNLNLTIPEPGLSTVQAVCGGVRCATVLISGRPVVVQPLLAASDALVAAWLPGSEGQGVTDA LFGDFGFTGRLPRTWFKSVDQLPMNVGDAHYDPLFRLGYGLTTNATKKY ; _entity_poly.pdbx_seq_one_letter_code_can ;HHAADYVLYKDATKPVEDRVADLLGRMTLAEKIGQMTQIERLVATPDVLRDNFIGSLLSGGGSVPRKGATAKEWQDMVDG FQKACMSTRLGIPMIYGIDAVHGQNNVYGATIFPHNVGLGATRDPYLVKRIGEATALEVRATGIQYAFAPCIAVCRDPRW GRCYESYSEDRRIVQSMTELIPGLQGDVPKDFTSGMPFVAGKNKVAACAKHFVGDGGTVDGINENNTIINREGLMNIHMP AYKNAMDKGVSTVMISYSSWNGVKMHANQDLVTGYLKDTLKFKGFVISDWEGIDRITTPAGSDYSYSVKASILAGLDMIM VPNKYQQFISILTGHVNGGVIPMSRIDDAVTRILRVKFTMGLFENPYADPAMAEQLGKQEHRDLAREAARKSLVLLKNGK TSTDAPLLPLPKKAPKILVAGSHADNLGYQCGGWTIEWQGDTGRTTVGTTILEAVKAAVDPSTVVVFAENPDAEFVKSGG FSYAIVAVGEHPYTETKGDNLNLTIPEPGLSTVQAVCGGVRCATVLISGRPVVVQPLLAASDALVAAWLPGSEGQGVTDA LFGDFGFTGRLPRTWFKSVDQLPMNVGDAHYDPLFRLGYGLTTNATKKY ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 HIS n 1 2 HIS n 1 3 ALA n 1 4 ALA n 1 5 ASP n 1 6 TYR n 1 7 VAL n 1 8 LEU n 1 9 TYR n 1 10 LYS n 1 11 ASP n 1 12 ALA n 1 13 THR n 1 14 LYS n 1 15 PRO n 1 16 VAL n 1 17 GLU n 1 18 ASP n 1 19 ARG n 1 20 VAL n 1 21 ALA n 1 22 ASP n 1 23 LEU n 1 24 LEU n 1 25 GLY n 1 26 ARG n 1 27 MET n 1 28 THR n 1 29 LEU n 1 30 ALA n 1 31 GLU n 1 32 LYS n 1 33 ILE n 1 34 GLY n 1 35 GLN n 1 36 MET n 1 37 THR n 1 38 GLN n 1 39 ILE n 1 40 GLU n 1 41 ARG n 1 42 LEU n 1 43 VAL n 1 44 ALA n 1 45 THR n 1 46 PRO n 1 47 ASP n 1 48 VAL n 1 49 LEU n 1 50 ARG n 1 51 ASP n 1 52 ASN n 1 53 PHE n 1 54 ILE n 1 55 GLY n 1 56 SER n 1 57 LEU n 1 58 LEU n 1 59 SER n 1 60 GLY n 1 61 GLY n 1 62 GLY n 1 63 SER n 1 64 VAL n 1 65 PRO n 1 66 ARG n 1 67 LYS n 1 68 GLY n 1 69 ALA n 1 70 THR n 1 71 ALA n 1 72 LYS n 1 73 GLU n 1 74 TRP n 1 75 GLN n 1 76 ASP n 1 77 MET n 1 78 VAL n 1 79 ASP n 1 80 GLY n 1 81 PHE n 1 82 GLN n 1 83 LYS n 1 84 ALA n 1 85 CYS n 1 86 MET n 1 87 SER n 1 88 THR n 1 89 ARG n 1 90 LEU n 1 91 GLY n 1 92 ILE n 1 93 PRO n 1 94 MET n 1 95 ILE n 1 96 TYR n 1 97 GLY n 1 98 ILE n 1 99 ASP n 1 100 ALA n 1 101 VAL n 1 102 HIS n 1 103 GLY n 1 104 GLN n 1 105 ASN n 1 106 ASN n 1 107 VAL n 1 108 TYR n 1 109 GLY n 1 110 ALA n 1 111 THR n 1 112 ILE n 1 113 PHE n 1 114 PRO n 1 115 HIS n 1 116 ASN n 1 117 VAL n 1 118 GLY n 1 119 LEU n 1 120 GLY n 1 121 ALA n 1 122 THR n 1 123 ARG n 1 124 ASP n 1 125 PRO n 1 126 TYR n 1 127 LEU n 1 128 VAL n 1 129 LYS n 1 130 ARG n 1 131 ILE n 1 132 GLY n 1 133 GLU n 1 134 ALA n 1 135 THR n 1 136 ALA n 1 137 LEU n 1 138 GLU n 1 139 VAL n 1 140 ARG n 1 141 ALA n 1 142 THR n 1 143 GLY n 1 144 ILE n 1 145 GLN n 1 146 TYR n 1 147 ALA n 1 148 PHE n 1 149 ALA n 1 150 PRO n 1 151 CYS n 1 152 ILE n 1 153 ALA n 1 154 VAL n 1 155 CYS n 1 156 ARG n 1 157 ASP n 1 158 PRO n 1 159 ARG n 1 160 TRP n 1 161 GLY n 1 162 ARG n 1 163 CYS n 1 164 TYR n 1 165 GLU n 1 166 SER n 1 167 TYR n 1 168 SER n 1 169 GLU n 1 170 ASP n 1 171 ARG n 1 172 ARG n 1 173 ILE n 1 174 VAL n 1 175 GLN n 1 176 SER n 1 177 MET n 1 178 THR n 1 179 GLU n 1 180 LEU n 1 181 ILE n 1 182 PRO n 1 183 GLY n 1 184 LEU n 1 185 GLN n 1 186 GLY n 1 187 ASP n 1 188 VAL n 1 189 PRO n 1 190 LYS n 1 191 ASP n 1 192 PHE n 1 193 THR n 1 194 SER n 1 195 GLY n 1 196 MET n 1 197 PRO n 1 198 PHE n 1 199 VAL n 1 200 ALA n 1 201 GLY n 1 202 LYS n 1 203 ASN n 1 204 LYS n 1 205 VAL n 1 206 ALA n 1 207 ALA n 1 208 CYS n 1 209 ALA n 1 210 LYS n 1 211 HIS n 1 212 PHE n 1 213 VAL n 1 214 GLY n 1 215 ASP n 1 216 GLY n 1 217 GLY n 1 218 THR n 1 219 VAL n 1 220 ASP n 1 221 GLY n 1 222 ILE n 1 223 ASN n 1 224 GLU n 1 225 ASN n 1 226 ASN n 1 227 THR n 1 228 ILE n 1 229 ILE n 1 230 ASN n 1 231 ARG n 1 232 GLU n 1 233 GLY n 1 234 LEU n 1 235 MET n 1 236 ASN n 1 237 ILE n 1 238 HIS n 1 239 MET n 1 240 PRO n 1 241 ALA n 1 242 TYR n 1 243 LYS n 1 244 ASN n 1 245 ALA n 1 246 MET n 1 247 ASP n 1 248 LYS n 1 249 GLY n 1 250 VAL n 1 251 SER n 1 252 THR n 1 253 VAL n 1 254 MET n 1 255 ILE n 1 256 SER n 1 257 TYR n 1 258 SER n 1 259 SER n 1 260 TRP n 1 261 ASN n 1 262 GLY n 1 263 VAL n 1 264 LYS n 1 265 MET n 1 266 HIS n 1 267 ALA n 1 268 ASN n 1 269 GLN n 1 270 ASP n 1 271 LEU n 1 272 VAL n 1 273 THR n 1 274 GLY n 1 275 TYR n 1 276 LEU n 1 277 LYS n 1 278 ASP n 1 279 THR n 1 280 LEU n 1 281 LYS n 1 282 PHE n 1 283 LYS n 1 284 GLY n 1 285 PHE n 1 286 VAL n 1 287 ILE n 1 288 SER n 1 289 ASP n 1 290 TRP n 1 291 GLU n 1 292 GLY n 1 293 ILE n 1 294 ASP n 1 295 ARG n 1 296 ILE n 1 297 THR n 1 298 THR n 1 299 PRO n 1 300 ALA n 1 301 GLY n 1 302 SER n 1 303 ASP n 1 304 TYR n 1 305 SER n 1 306 TYR n 1 307 SER n 1 308 VAL n 1 309 LYS n 1 310 ALA n 1 311 SER n 1 312 ILE n 1 313 LEU n 1 314 ALA n 1 315 GLY n 1 316 LEU n 1 317 ASP n 1 318 MET n 1 319 ILE n 1 320 MET n 1 321 VAL n 1 322 PRO n 1 323 ASN n 1 324 LYS n 1 325 TYR n 1 326 GLN n 1 327 GLN n 1 328 PHE n 1 329 ILE n 1 330 SER n 1 331 ILE n 1 332 LEU n 1 333 THR n 1 334 GLY n 1 335 HIS n 1 336 VAL n 1 337 ASN n 1 338 GLY n 1 339 GLY n 1 340 VAL n 1 341 ILE n 1 342 PRO n 1 343 MET n 1 344 SER n 1 345 ARG n 1 346 ILE n 1 347 ASP n 1 348 ASP n 1 349 ALA n 1 350 VAL n 1 351 THR n 1 352 ARG n 1 353 ILE n 1 354 LEU n 1 355 ARG n 1 356 VAL n 1 357 LYS n 1 358 PHE n 1 359 THR n 1 360 MET n 1 361 GLY n 1 362 LEU n 1 363 PHE n 1 364 GLU n 1 365 ASN n 1 366 PRO n 1 367 TYR n 1 368 ALA n 1 369 ASP n 1 370 PRO n 1 371 ALA n 1 372 MET n 1 373 ALA n 1 374 GLU n 1 375 GLN n 1 376 LEU n 1 377 GLY n 1 378 LYS n 1 379 GLN n 1 380 GLU n 1 381 HIS n 1 382 ARG n 1 383 ASP n 1 384 LEU n 1 385 ALA n 1 386 ARG n 1 387 GLU n 1 388 ALA n 1 389 ALA n 1 390 ARG n 1 391 LYS n 1 392 SER n 1 393 LEU n 1 394 VAL n 1 395 LEU n 1 396 LEU n 1 397 LYS n 1 398 ASN n 1 399 GLY n 1 400 LYS n 1 401 THR n 1 402 SER n 1 403 THR n 1 404 ASP n 1 405 ALA n 1 406 PRO n 1 407 LEU n 1 408 LEU n 1 409 PRO n 1 410 LEU n 1 411 PRO n 1 412 LYS n 1 413 LYS n 1 414 ALA n 1 415 PRO n 1 416 LYS n 1 417 ILE n 1 418 LEU n 1 419 VAL n 1 420 ALA n 1 421 GLY n 1 422 SER n 1 423 HIS n 1 424 ALA n 1 425 ASP n 1 426 ASN n 1 427 LEU n 1 428 GLY n 1 429 TYR n 1 430 GLN n 1 431 CYS n 1 432 GLY n 1 433 GLY n 1 434 TRP n 1 435 THR n 1 436 ILE n 1 437 GLU n 1 438 TRP n 1 439 GLN n 1 440 GLY n 1 441 ASP n 1 442 THR n 1 443 GLY n 1 444 ARG n 1 445 THR n 1 446 THR n 1 447 VAL n 1 448 GLY n 1 449 THR n 1 450 THR n 1 451 ILE n 1 452 LEU n 1 453 GLU n 1 454 ALA n 1 455 VAL n 1 456 LYS n 1 457 ALA n 1 458 ALA n 1 459 VAL n 1 460 ASP n 1 461 PRO n 1 462 SER n 1 463 THR n 1 464 VAL n 1 465 VAL n 1 466 VAL n 1 467 PHE n 1 468 ALA n 1 469 GLU n 1 470 ASN n 1 471 PRO n 1 472 ASP n 1 473 ALA n 1 474 GLU n 1 475 PHE n 1 476 VAL n 1 477 LYS n 1 478 SER n 1 479 GLY n 1 480 GLY n 1 481 PHE n 1 482 SER n 1 483 TYR n 1 484 ALA n 1 485 ILE n 1 486 VAL n 1 487 ALA n 1 488 VAL n 1 489 GLY n 1 490 GLU n 1 491 HIS n 1 492 PRO n 1 493 TYR n 1 494 THR n 1 495 GLU n 1 496 THR n 1 497 LYS n 1 498 GLY n 1 499 ASP n 1 500 ASN n 1 501 LEU n 1 502 ASN n 1 503 LEU n 1 504 THR n 1 505 ILE n 1 506 PRO n 1 507 GLU n 1 508 PRO n 1 509 GLY n 1 510 LEU n 1 511 SER n 1 512 THR n 1 513 VAL n 1 514 GLN n 1 515 ALA n 1 516 VAL n 1 517 CYS n 1 518 GLY n 1 519 GLY n 1 520 VAL n 1 521 ARG n 1 522 CYS n 1 523 ALA n 1 524 THR n 1 525 VAL n 1 526 LEU n 1 527 ILE n 1 528 SER n 1 529 GLY n 1 530 ARG n 1 531 PRO n 1 532 VAL n 1 533 VAL n 1 534 VAL n 1 535 GLN n 1 536 PRO n 1 537 LEU n 1 538 LEU n 1 539 ALA n 1 540 ALA n 1 541 SER n 1 542 ASP n 1 543 ALA n 1 544 LEU n 1 545 VAL n 1 546 ALA n 1 547 ALA n 1 548 TRP n 1 549 LEU n 1 550 PRO n 1 551 GLY n 1 552 SER n 1 553 GLU n 1 554 GLY n 1 555 GLN n 1 556 GLY n 1 557 VAL n 1 558 THR n 1 559 ASP n 1 560 ALA n 1 561 LEU n 1 562 PHE n 1 563 GLY n 1 564 ASP n 1 565 PHE n 1 566 GLY n 1 567 PHE n 1 568 THR n 1 569 GLY n 1 570 ARG n 1 571 LEU n 1 572 PRO n 1 573 ARG n 1 574 THR n 1 575 TRP n 1 576 PHE n 1 577 LYS n 1 578 SER n 1 579 VAL n 1 580 ASP n 1 581 GLN n 1 582 LEU n 1 583 PRO n 1 584 MET n 1 585 ASN n 1 586 VAL n 1 587 GLY n 1 588 ASP n 1 589 ALA n 1 590 HIS n 1 591 TYR n 1 592 ASP n 1 593 PRO n 1 594 LEU n 1 595 PHE n 1 596 ARG n 1 597 LEU n 1 598 GLY n 1 599 TYR n 1 600 GLY n 1 601 LEU n 1 602 THR n 1 603 THR n 1 604 ASN n 1 605 ALA n 1 606 THR n 1 607 LYS n 1 608 LYS n 1 609 TYR n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'barley,two-rowed barley' _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene ? _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Hordeum vulgare subsp. vulgare' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 112509 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Komagataella pastoris' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 4922 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain SMD11680H _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type plasmid _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pPICZalphaBNH8/DEST _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code Q9XEI3_HORVD _struct_ref.pdbx_db_accession Q9XEI3 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;DYVLYKDATKPVEDRVADLLGRMTLAEKIGQMTQIERLVATPDVLRDNFIGSLLSGGGSVPRKGATAKEWQDMVDGFQKA CMSTRLGIPMIYGIDAVHGQNNVYGATIFPHNVGLGATRDPYLVKRIGEATALEVRATGIQYAFAPCIAVCRDPRWGRCY ESYSEDRRIVQSMTELIPGLQGDVPKDFTSGMPFVAGKNKVAACAKHFVGDGGTVDGINENNTIINREGLMNIHMPAYKN AMDKGVSTVMISYSSWNGVKMHANQDLVTGYLKDTLKFKGFVISDWEGIDRITTPAGSDYSYSVKASILAGLDMIMVPNN YQQFISILTGHVNGGVIPMSRIDDAVTRILRVKFTMGLFENPYADPAMAEQLGKQEHRDLAREAARKSLVLLKNGKTSTD APLLPLPKKAPKILVAGSHADNLGYQCGGWTIEWQGDTGRTTVGTTILEAVKAAVDPSTVVVFAENPDAEFVKSGGFSYA IVAVGEHPYTETKGDNLNLTIPEPGLSTVQAVCGGVRCATVLISGRPVVVQPLLAASDALVAAWLPGSEGQGVTDALFGD FGFTGRLPRTWFKSVDQLPMNVGDAHYDPLFRLGYGLTTNATKKY ; _struct_ref.pdbx_align_begin 26 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 3WLO _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 5 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 609 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession Q9XEI3 _struct_ref_seq.db_align_beg 26 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 630 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 1 _struct_ref_seq.pdbx_auth_seq_align_end 605 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3WLO HIS A 1 ? UNP Q9XEI3 ? ? 'EXPRESSION TAG' -3 1 1 3WLO HIS A 2 ? UNP Q9XEI3 ? ? 'EXPRESSION TAG' -2 2 1 3WLO ALA A 3 ? UNP Q9XEI3 ? ? 'EXPRESSION TAG' -1 3 1 3WLO ALA A 4 ? UNP Q9XEI3 ? ? 'EXPRESSION TAG' 0 4 1 3WLO LYS A 324 ? UNP Q9XEI3 ASN 345 'SEE REMARK 999' 320 5 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BGC saccharide . BETA-D-GLUCOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 3WLO _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 3.51 _exptl_crystal.density_percent_sol 64.91 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 277 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 7.0 _exptl_crystal_grow.pdbx_details '75mM HEPES-NaOH pH7.0, 1.2% PEG 400, 1.7M ammonium sulphate, VAPOR DIFFUSION, HANGING DROP, temperature 277K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp ? _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 210r' _diffrn_detector.pdbx_collection_date ? _diffrn_detector.details 'collimating mirrors' # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'double-crystal Si(111) monochromator' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.0 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'AUSTRALIAN SYNCHROTRON BEAMLINE MX1' _diffrn_source.pdbx_synchrotron_site 'Australian Synchrotron' _diffrn_source.pdbx_synchrotron_beamline MX1 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.0 # _reflns.entry_id 3WLO _reflns.observed_criterion_sigma_I 1.0 _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 87.86 _reflns.d_resolution_high 1.55 _reflns.number_obs 127330 _reflns.number_all 127330 _reflns.percent_possible_obs 99.5 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI ? _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy ? _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 1.55 _reflns_shell.d_res_low 1.59 _reflns_shell.percent_possible_all 97.6 _reflns_shell.Rmerge_I_obs 0.990 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 1.8 _reflns_shell.pdbx_redundancy ? _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_rejects ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.number_possible ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.meanI_over_sigI_all ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 3WLO _refine.ls_number_reflns_obs 127330 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 48.31 _refine.ls_d_res_high 1.55 _refine.ls_percent_reflns_obs 99.53 _refine.ls_R_factor_obs 0.16780 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.16661 _refine.ls_R_factor_R_free 0.19017 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.0 _refine.ls_number_reflns_R_free 6728 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.971 _refine.correlation_coeff_Fo_to_Fc_free 0.965 _refine.B_iso_mean 23.469 _refine.aniso_B[1][1] 0.46 _refine.aniso_B[2][2] 0.46 _refine.aniso_B[3][3] -0.93 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details 'BABINET MODEL WITH MASK' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.40 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model 1IEQ _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.062 _refine.pdbx_overall_ESU_R_Free 0.064 _refine.overall_SU_ML 0.040 _refine.pdbx_overall_phase_error ? _refine.overall_SU_B 1.120 _refine.overall_SU_R_Cruickshank_DPI ? _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_diffrn_id 1 _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 4596 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 71 _refine_hist.number_atoms_solvent 1025 _refine_hist.number_atoms_total 5692 _refine_hist.d_res_high 1.55 _refine_hist.d_res_low 48.31 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_restraint_function _refine_ls_restr.pdbx_refine_id r_bond_refined_d 0.021 0.022 ? 4820 ? 'X-RAY DIFFRACTION' r_bond_other_d ? ? ? ? ? 'X-RAY DIFFRACTION' r_angle_refined_deg 1.845 1.981 ? 6552 ? 'X-RAY DIFFRACTION' r_angle_other_deg ? ? ? ? ? 'X-RAY DIFFRACTION' r_dihedral_angle_1_deg 6.522 5.000 ? 605 ? 'X-RAY DIFFRACTION' r_dihedral_angle_2_deg 37.835 23.939 ? 198 ? 'X-RAY DIFFRACTION' r_dihedral_angle_3_deg 13.082 15.000 ? 776 ? 'X-RAY DIFFRACTION' r_dihedral_angle_4_deg 16.410 15.000 ? 30 ? 'X-RAY DIFFRACTION' r_chiral_restr 0.134 0.200 ? 752 ? 'X-RAY DIFFRACTION' r_gen_planes_refined 0.010 0.021 ? 3612 ? 'X-RAY DIFFRACTION' r_gen_planes_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_nbd_refined ? ? ? ? ? 'X-RAY DIFFRACTION' r_nbd_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_nbtor_refined ? ? ? ? ? 'X-RAY DIFFRACTION' r_nbtor_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_xyhbond_nbd_refined ? ? ? ? ? 'X-RAY DIFFRACTION' r_xyhbond_nbd_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_metal_ion_refined ? ? ? ? ? 'X-RAY DIFFRACTION' r_metal_ion_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_symmetry_vdw_refined ? ? ? ? ? 'X-RAY DIFFRACTION' r_symmetry_vdw_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_symmetry_hbond_refined ? ? ? ? ? 'X-RAY DIFFRACTION' r_symmetry_hbond_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_symmetry_metal_ion_refined ? ? ? ? ? 'X-RAY DIFFRACTION' r_symmetry_metal_ion_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_mcbond_it 1.045 1.500 ? 2999 ? 'X-RAY DIFFRACTION' r_mcbond_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_mcangle_it 1.726 2.000 ? 4832 ? 'X-RAY DIFFRACTION' r_mcangle_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_scbond_it 2.873 3.000 ? 1821 ? 'X-RAY DIFFRACTION' r_scbond_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_scangle_it 4.471 4.500 ? 1720 ? 'X-RAY DIFFRACTION' r_scangle_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_long_range_B_refined ? ? ? ? ? 'X-RAY DIFFRACTION' r_long_range_B_other ? ? ? ? ? 'X-RAY DIFFRACTION' r_rigid_bond_restr ? ? ? ? ? 'X-RAY DIFFRACTION' r_sphericity_free ? ? ? ? ? 'X-RAY DIFFRACTION' r_sphericity_bonded ? ? ? ? ? 'X-RAY DIFFRACTION' # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 1.551 _refine_ls_shell.d_res_low 1.591 _refine_ls_shell.number_reflns_R_work 9197 _refine_ls_shell.R_factor_R_work 0.296 _refine_ls_shell.percent_reflns_obs 97.58 _refine_ls_shell.R_factor_R_free 0.321 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 442 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? # _struct.entry_id 3WLO _struct.title 'Crystal Structure Analysis of Plant Exohydrolase' _struct.pdbx_descriptor 'Beta-D-glucan exohydrolase isoenzyme ExoI (E.C.3.2.1.-)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3WLO _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'BETA BARREL, HYDROLASE, GRAIN DEVELOPMENT, Tim Barrel/Beta sheet, N-glycosylation, plant apoplast, Enzyme Function Initiative' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 2 ? E N N 3 ? F N N 3 ? G N N 4 ? H N N 5 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 VAL A 7 ? ASP A 11 ? VAL A 3 ASP A 7 5 ? 5 HELX_P HELX_P2 2 PRO A 15 ? GLY A 25 ? PRO A 11 GLY A 21 1 ? 11 HELX_P HELX_P3 3 THR A 28 ? MET A 36 ? THR A 24 MET A 32 1 ? 9 HELX_P HELX_P4 4 LEU A 42 ? ALA A 44 ? LEU A 38 ALA A 40 5 ? 3 HELX_P HELX_P5 5 THR A 45 ? ASN A 52 ? THR A 41 ASN A 48 1 ? 8 HELX_P HELX_P6 6 THR A 70 ? SER A 87 ? THR A 66 SER A 83 1 ? 18 HELX_P HELX_P7 7 HIS A 115 ? THR A 122 ? HIS A 111 THR A 118 1 ? 8 HELX_P HELX_P8 8 ASP A 124 ? ALA A 141 ? ASP A 120 ALA A 137 1 ? 18 HELX_P HELX_P9 9 ARG A 162 ? SER A 166 ? ARG A 158 SER A 162 5 ? 5 HELX_P HELX_P10 10 ASP A 170 ? THR A 178 ? ASP A 166 THR A 174 1 ? 9 HELX_P HELX_P11 11 GLU A 179 ? GLY A 186 ? GLU A 175 GLY A 182 1 ? 8 HELX_P HELX_P12 12 GLY A 214 ? ILE A 222 ? GLY A 210 ILE A 218 5 ? 9 HELX_P HELX_P13 13 ASN A 230 ? HIS A 238 ? ASN A 226 HIS A 234 1 ? 9 HELX_P HELX_P14 14 MET A 239 ? LYS A 248 ? MET A 235 LYS A 244 1 ? 10 HELX_P HELX_P15 15 ASN A 268 ? THR A 273 ? ASN A 264 THR A 269 1 ? 6 HELX_P HELX_P16 16 ILE A 293 ? THR A 297 ? ILE A 289 THR A 293 5 ? 5 HELX_P HELX_P17 17 ASP A 303 ? GLY A 315 ? ASP A 299 GLY A 311 1 ? 13 HELX_P HELX_P18 18 LYS A 324 ? GLY A 338 ? LYS A 320 GLY A 334 1 ? 15 HELX_P HELX_P19 19 PRO A 342 ? MET A 360 ? PRO A 338 MET A 356 1 ? 19 HELX_P HELX_P20 20 ASP A 369 ? LEU A 376 ? ASP A 365 LEU A 372 5 ? 8 HELX_P HELX_P21 21 LYS A 378 ? LEU A 393 ? LYS A 374 LEU A 389 1 ? 16 HELX_P HELX_P22 22 ASN A 426 ? GLY A 432 ? ASN A 422 GLY A 428 1 ? 7 HELX_P HELX_P23 23 THR A 450 ? VAL A 459 ? THR A 446 VAL A 455 1 ? 10 HELX_P HELX_P24 24 ASP A 472 ? SER A 478 ? ASP A 468 SER A 474 1 ? 7 HELX_P HELX_P25 25 THR A 494 ? ASP A 499 ? THR A 490 ASP A 495 5 ? 6 HELX_P HELX_P26 26 PRO A 508 ? VAL A 520 ? PRO A 504 VAL A 516 1 ? 13 HELX_P HELX_P27 27 VAL A 534 ? SER A 541 ? VAL A 530 SER A 537 1 ? 8 HELX_P HELX_P28 28 GLY A 554 ? PHE A 562 ? GLY A 550 PHE A 558 1 ? 9 HELX_P HELX_P29 29 SER A 578 ? LEU A 582 ? SER A 574 LEU A 578 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 155 SG ? ? ? 1_555 A CYS 163 SG ? ? A CYS 151 A CYS 159 1_555 ? ? ? ? ? ? ? 2.256 ? disulf2 disulf ? ? A CYS 517 SG ? ? ? 1_555 A CYS 522 SG ? ? A CYS 513 A CYS 518 1_555 ? ? ? ? ? ? ? 2.019 ? covale1 covale ? ? A ASN 225 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 221 A NAG 701 1_555 ? ? ? ? ? ? ? 1.441 ? covale2 covale ? ? A ASN 502 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 498 A NAG 702 1_555 ? ? ? ? ? ? ? 1.447 ? covale3 covale ? ? A ASN 604 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 600 A NAG 703 1_555 ? ? ? ? ? ? ? 1.450 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ALA 149 A . ? ALA 145 A PRO 150 A ? PRO 146 A 1 2.15 2 LYS 210 A . ? LYS 206 A HIS 211 A ? HIS 207 A 1 -5.99 3 PHE 212 A . ? PHE 208 A VAL 213 A ? VAL 209 A 1 -6.82 4 THR 298 A . ? THR 294 A PRO 299 A ? PRO 295 A 1 -5.40 5 VAL 321 A . ? VAL 317 A PRO 322 A ? PRO 318 A 1 -14.67 6 LEU 408 A . ? LEU 404 A PRO 409 A ? PRO 405 A 1 1.05 7 GLU 507 A . ? GLU 503 A PRO 508 A ? PRO 504 A 1 12.70 8 LEU 582 A . ? LEU 578 A PRO 583 A ? PRO 579 A 1 -3.29 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 5 ? B ? 3 ? C ? 3 ? D ? 6 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? parallel A 4 5 ? parallel B 1 2 ? parallel B 2 3 ? parallel C 1 2 ? parallel C 2 3 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? parallel D 3 4 ? parallel D 4 5 ? parallel D 5 6 ? parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 TYR A 146 ? ALA A 147 ? TYR A 142 ALA A 143 A 2 ILE A 95 ? ILE A 98 ? ILE A 91 ILE A 94 A 3 SER A 56 ? SER A 59 ? SER A 52 SER A 55 A 4 THR A 37 ? GLU A 40 ? THR A 33 GLU A 36 A 5 ILE A 319 ? MET A 320 ? ILE A 315 MET A 316 B 1 CYS A 208 ? PHE A 212 ? CYS A 204 PHE A 208 B 2 THR A 252 ? ILE A 255 ? THR A 248 ILE A 251 B 3 PHE A 285 ? ILE A 287 ? PHE A 281 ILE A 283 C 1 ASN A 226 ? THR A 227 ? ASN A 222 THR A 223 C 2 SER A 259 ? TRP A 260 ? SER A 255 TRP A 256 C 3 VAL A 263 ? LYS A 264 ? VAL A 259 LYS A 260 D 1 VAL A 394 ? ASN A 398 ? VAL A 390 ASN A 394 D 2 ALA A 543 ? TRP A 548 ? ALA A 539 TRP A 544 D 3 CYS A 522 ? ILE A 527 ? CYS A 518 ILE A 523 D 4 ALA A 484 ? GLY A 489 ? ALA A 480 GLY A 485 D 5 LYS A 416 ? ALA A 420 ? LYS A 412 ALA A 416 D 6 VAL A 464 ? ALA A 468 ? VAL A 460 ALA A 464 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 O TYR A 146 ? O TYR A 142 N ILE A 98 ? N ILE A 94 A 2 3 O GLY A 97 ? O GLY A 93 N LEU A 57 ? N LEU A 53 A 3 4 O SER A 56 ? O SER A 52 N ILE A 39 ? N ILE A 35 A 4 5 N GLN A 38 ? N GLN A 34 O ILE A 319 ? O ILE A 315 B 1 2 N PHE A 212 ? N PHE A 208 O MET A 254 ? O MET A 250 B 2 3 N VAL A 253 ? N VAL A 249 O ILE A 287 ? O ILE A 283 C 1 2 N THR A 227 ? N THR A 223 O SER A 259 ? O SER A 255 C 2 3 N TRP A 260 ? N TRP A 256 O VAL A 263 ? O VAL A 259 D 1 2 N VAL A 394 ? N VAL A 390 O ALA A 546 ? O ALA A 542 D 2 3 O VAL A 545 ? O VAL A 541 N LEU A 526 ? N LEU A 522 D 3 4 O ILE A 527 ? O ILE A 523 N VAL A 488 ? N VAL A 484 D 4 5 O ALA A 487 ? O ALA A 483 N ALA A 420 ? N ALA A 416 D 5 6 N ILE A 417 ? N ILE A 413 O VAL A 464 ? O VAL A 460 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 16 'BINDING SITE FOR RESIDUE BGC A 704' AC2 Software ? ? ? ? 13 'BINDING SITE FOR RESIDUE BGC A 705' AC3 Software ? ? ? ? 13 'BINDING SITE FOR RESIDUE BGC A 705' AC4 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE SO4 A 706' AC5 Software ? ? ? ? 5 'BINDING SITE FOR MONO-SACCHARIDE NAG A 701 BOUND TO ASN A 221' AC6 Software ? ? ? ? 7 'BINDING SITE FOR MONO-SACCHARIDE NAG A 702 BOUND TO ASN A 498' AC7 Software ? ? ? ? 6 'BINDING SITE FOR MONO-SACCHARIDE NAG A 703 BOUND TO ASN A 600' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 16 LEU A 58 ? LEU A 54 . ? 1_555 ? 2 AC1 16 GLY A 60 ? GLY A 56 . ? 1_555 ? 3 AC1 16 ASP A 99 ? ASP A 95 . ? 1_555 ? 4 AC1 16 PHE A 148 ? PHE A 144 . ? 1_555 ? 5 AC1 16 ARG A 162 ? ARG A 158 . ? 1_555 ? 6 AC1 16 LYS A 210 ? LYS A 206 . ? 1_555 ? 7 AC1 16 HIS A 211 ? HIS A 207 . ? 1_555 ? 8 AC1 16 MET A 254 ? MET A 250 . ? 1_555 ? 9 AC1 16 TYR A 257 ? TYR A 253 . ? 1_555 ? 10 AC1 16 ASP A 289 ? ASP A 285 . ? 1_555 ? 11 AC1 16 TRP A 290 ? TRP A 286 . ? 1_555 ? 12 AC1 16 MET A 320 ? MET A 316 . ? 1_555 ? 13 AC1 16 TRP A 434 ? TRP A 430 . ? 1_555 ? 14 AC1 16 GLU A 495 ? GLU A 491 . ? 1_555 ? 15 AC1 16 BGC F . ? BGC A 705 . ? 1_555 ? 16 AC1 16 HOH H . ? HOH A 801 . ? 1_555 ? 17 AC2 13 GLY A 60 ? GLY A 56 . ? 1_555 ? 18 AC2 13 GLY A 61 ? GLY A 57 . ? 1_555 ? 19 AC2 13 ASP A 99 ? ASP A 95 . ? 1_555 ? 20 AC2 13 TYR A 257 ? TYR A 253 . ? 1_555 ? 21 AC2 13 TRP A 290 ? TRP A 286 . ? 1_555 ? 22 AC2 13 TRP A 434 ? TRP A 430 . ? 1_555 ? 23 AC2 13 TRP A 438 ? TRP A 434 . ? 1_555 ? 24 AC2 13 BGC E . ? BGC A 704 . ? 1_555 ? 25 AC2 13 BGC F . ? BGC A 705 . ? 1_555 ? 26 AC2 13 HOH H . ? HOH A 801 . ? 1_555 ? 27 AC2 13 HOH H . ? HOH A 942 . ? 1_555 ? 28 AC2 13 HOH H . ? HOH A 1602 . ? 1_555 ? 29 AC2 13 HOH H . ? HOH A 1796 . ? 1_555 ? 30 AC3 13 GLY A 60 ? GLY A 56 . ? 1_555 ? 31 AC3 13 GLY A 61 ? GLY A 57 . ? 1_555 ? 32 AC3 13 ASP A 99 ? ASP A 95 . ? 1_555 ? 33 AC3 13 TYR A 257 ? TYR A 253 . ? 1_555 ? 34 AC3 13 TRP A 290 ? TRP A 286 . ? 1_555 ? 35 AC3 13 TRP A 434 ? TRP A 430 . ? 1_555 ? 36 AC3 13 TRP A 438 ? TRP A 434 . ? 1_555 ? 37 AC3 13 BGC E . ? BGC A 704 . ? 1_555 ? 38 AC3 13 BGC F . ? BGC A 705 . ? 1_555 ? 39 AC3 13 HOH H . ? HOH A 801 . ? 1_555 ? 40 AC3 13 HOH H . ? HOH A 942 . ? 1_555 ? 41 AC3 13 HOH H . ? HOH A 1602 . ? 1_555 ? 42 AC3 13 HOH H . ? HOH A 1796 . ? 1_555 ? 43 AC4 7 PRO A 342 ? PRO A 338 . ? 1_555 ? 44 AC4 7 MET A 343 ? MET A 339 . ? 1_555 ? 45 AC4 7 SER A 344 ? SER A 340 . ? 1_555 ? 46 AC4 7 HOH H . ? HOH A 897 . ? 1_555 ? 47 AC4 7 HOH H . ? HOH A 1477 . ? 1_555 ? 48 AC4 7 HOH H . ? HOH A 1564 . ? 1_555 ? 49 AC4 7 HOH H . ? HOH A 1784 . ? 1_555 ? 50 AC5 5 GLU A 224 ? GLU A 220 . ? 1_555 ? 51 AC5 5 ASN A 225 ? ASN A 221 . ? 1_555 ? 52 AC5 5 SER A 259 ? SER A 255 . ? 1_555 ? 53 AC5 5 HOH H . ? HOH A 1297 . ? 1_555 ? 54 AC5 5 HOH H . ? HOH A 1370 . ? 1_555 ? 55 AC6 7 ASP A 499 ? ASP A 495 . ? 1_555 ? 56 AC6 7 ASN A 500 ? ASN A 496 . ? 1_555 ? 57 AC6 7 ASN A 502 ? ASN A 498 . ? 1_555 ? 58 AC6 7 HOH H . ? HOH A 872 . ? 1_555 ? 59 AC6 7 HOH H . ? HOH A 879 . ? 1_555 ? 60 AC6 7 HOH H . ? HOH A 1349 . ? 1_555 ? 61 AC6 7 HOH H . ? HOH A 1597 . ? 1_555 ? 62 AC7 6 ASN A 604 ? ASN A 600 . ? 1_555 ? 63 AC7 6 HOH H . ? HOH A 874 . ? 1_555 ? 64 AC7 6 HOH H . ? HOH A 903 . ? 1_555 ? 65 AC7 6 HOH H . ? HOH A 1150 . ? 1_555 ? 66 AC7 6 HOH H . ? HOH A 1416 . ? 4_455 ? 67 AC7 6 HOH H . ? HOH A 1642 . ? 4_455 ? # _database_PDB_matrix.entry_id 3WLO _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 3WLO _atom_sites.fract_transf_matrix[1][1] 0.009984 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009984 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.005464 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . HIS A 1 1 ? 22.971 -1.027 1.488 1.00 72.28 ? -3 HIS A N 1 ATOM 2 C CA . HIS A 1 1 ? 21.493 -1.206 1.355 1.00 72.63 ? -3 HIS A CA 1 ATOM 3 C C . HIS A 1 1 ? 20.848 -0.170 0.407 1.00 72.11 ? -3 HIS A C 1 ATOM 4 O O . HIS A 1 1 ? 19.799 0.425 0.712 1.00 72.18 ? -3 HIS A O 1 ATOM 5 C CB . HIS A 1 1 ? 20.795 -1.281 2.731 1.00 73.02 ? -3 HIS A CB 1 ATOM 6 C CG . HIS A 1 1 ? 20.685 -2.674 3.291 1.00 75.00 ? -3 HIS A CG 1 ATOM 7 N ND1 . HIS A 1 1 ? 19.511 -3.403 3.258 1.00 76.68 ? -3 HIS A ND1 1 ATOM 8 C CD2 . HIS A 1 1 ? 21.601 -3.471 3.896 1.00 76.03 ? -3 HIS A CD2 1 ATOM 9 C CE1 . HIS A 1 1 ? 19.710 -4.586 3.815 1.00 76.96 ? -3 HIS A CE1 1 ATOM 10 N NE2 . HIS A 1 1 ? 20.971 -4.653 4.210 1.00 76.77 ? -3 HIS A NE2 1 ATOM 11 N N . HIS A 1 2 ? 21.545 0.070 -0.710 1.00 71.34 ? -2 HIS A N 1 ATOM 12 C CA . HIS A 1 2 ? 20.938 0.346 -2.045 1.00 70.42 ? -2 HIS A CA 1 ATOM 13 C C . HIS A 1 2 ? 21.601 1.315 -3.012 1.00 68.61 ? -2 HIS A C 1 ATOM 14 O O . HIS A 1 2 ? 22.505 0.893 -3.743 1.00 68.70 ? -2 HIS A O 1 ATOM 15 C CB . HIS A 1 2 ? 19.397 0.368 -2.070 1.00 71.21 ? -2 HIS A CB 1 ATOM 16 C CG . HIS A 1 2 ? 18.802 -0.984 -2.330 1.00 73.69 ? -2 HIS A CG 1 ATOM 17 N ND1 . HIS A 1 2 ? 17.993 -1.249 -3.418 1.00 76.30 ? -2 HIS A ND1 1 ATOM 18 C CD2 . HIS A 1 2 ? 18.945 -2.161 -1.670 1.00 75.26 ? -2 HIS A CD2 1 ATOM 19 C CE1 . HIS A 1 2 ? 17.636 -2.523 -3.396 1.00 76.93 ? -2 HIS A CE1 1 ATOM 20 N NE2 . HIS A 1 2 ? 18.200 -3.098 -2.346 1.00 76.42 ? -2 HIS A NE2 1 ATOM 21 N N . ALA A 1 3 ? 21.175 2.586 -3.036 1.00 66.05 ? -1 ALA A N 1 ATOM 22 C CA . ALA A 1 3 ? 21.786 3.589 -3.941 1.00 63.31 ? -1 ALA A CA 1 ATOM 23 C C . ALA A 1 3 ? 23.332 3.549 -3.883 1.00 61.40 ? -1 ALA A C 1 ATOM 24 O O . ALA A 1 3 ? 23.915 3.114 -2.875 1.00 60.98 ? -1 ALA A O 1 ATOM 25 C CB . ALA A 1 3 ? 21.248 5.010 -3.655 1.00 63.40 ? -1 ALA A CB 1 ATOM 26 N N . ALA A 1 4 ? 23.995 3.971 -4.962 1.00 58.55 ? 0 ALA A N 1 ATOM 27 C CA . ALA A 1 4 ? 25.463 3.880 -5.029 1.00 55.60 ? 0 ALA A CA 1 ATOM 28 C C . ALA A 1 4 ? 26.200 4.772 -4.003 1.00 53.36 ? 0 ALA A C 1 ATOM 29 O O . ALA A 1 4 ? 27.351 4.486 -3.648 1.00 53.17 ? 0 ALA A O 1 ATOM 30 C CB . ALA A 1 4 ? 25.965 4.145 -6.459 1.00 56.28 ? 0 ALA A CB 1 ATOM 31 N N . ASP A 1 5 ? 25.527 5.831 -3.537 1.00 49.67 ? 1 ASP A N 1 ATOM 32 C CA . ASP A 1 5 ? 26.075 6.774 -2.544 1.00 46.29 ? 1 ASP A CA 1 ATOM 33 C C . ASP A 1 5 ? 25.589 6.493 -1.095 1.00 43.02 ? 1 ASP A C 1 ATOM 34 O O . ASP A 1 5 ? 25.556 7.386 -0.234 1.00 41.98 ? 1 ASP A O 1 ATOM 35 C CB . ASP A 1 5 ? 25.690 8.200 -2.927 1.00 46.98 ? 1 ASP A CB 1 ATOM 36 C CG . ASP A 1 5 ? 24.198 8.459 -2.761 1.00 49.71 ? 1 ASP A CG 1 ATOM 37 O OD1 . ASP A 1 5 ? 23.387 7.511 -2.967 1.00 51.61 ? 1 ASP A OD1 1 ATOM 38 O OD2 . ASP A 1 5 ? 23.841 9.609 -2.397 1.00 51.74 ? 1 ASP A OD2 1 ATOM 39 N N . TYR A 1 6 ? 25.205 5.253 -0.841 1.00 39.12 ? 2 TYR A N 1 ATOM 40 C CA . TYR A 1 6 ? 24.694 4.857 0.464 1.00 35.24 ? 2 TYR A CA 1 ATOM 41 C C . TYR A 1 6 ? 25.758 5.016 1.574 1.00 33.23 ? 2 TYR A C 1 ATOM 42 O O . TYR A 1 6 ? 26.922 4.649 1.402 1.00 32.75 ? 2 TYR A O 1 ATOM 43 C CB . TYR A 1 6 ? 24.217 3.421 0.382 1.00 35.14 ? 2 TYR A CB 1 ATOM 44 C CG . TYR A 1 6 ? 23.722 2.828 1.673 1.00 32.79 ? 2 TYR A CG 1 ATOM 45 C CD1 . TYR A 1 6 ? 22.396 3.008 2.079 1.00 31.36 ? 2 TYR A CD1 1 ATOM 46 C CD2 . TYR A 1 6 ? 24.556 2.053 2.458 1.00 29.70 ? 2 TYR A CD2 1 ATOM 47 C CE1 . TYR A 1 6 ? 21.943 2.431 3.259 1.00 27.19 ? 2 TYR A CE1 1 ATOM 48 C CE2 . TYR A 1 6 ? 24.123 1.488 3.621 1.00 28.70 ? 2 TYR A CE2 1 ATOM 49 C CZ . TYR A 1 6 ? 22.819 1.699 4.028 1.00 24.96 ? 2 TYR A CZ 1 ATOM 50 O OH . TYR A 1 6 ? 22.433 1.119 5.177 1.00 28.20 ? 2 TYR A OH 1 ATOM 51 N N . VAL A 1 7 ? 25.318 5.518 2.724 1.00 29.54 ? 3 VAL A N 1 ATOM 52 C CA . VAL A 1 7 ? 26.156 5.666 3.912 1.00 26.47 ? 3 VAL A CA 1 ATOM 53 C C . VAL A 1 7 ? 25.341 5.061 5.082 1.00 24.29 ? 3 VAL A C 1 ATOM 54 O O . VAL A 1 7 ? 24.258 5.569 5.405 1.00 24.52 ? 3 VAL A O 1 ATOM 55 C CB . VAL A 1 7 ? 26.452 7.179 4.082 1.00 27.00 ? 3 VAL A CB 1 ATOM 56 C CG1 . VAL A 1 7 ? 26.988 7.517 5.433 1.00 28.03 ? 3 VAL A CG1 1 ATOM 57 C CG2 . VAL A 1 7 ? 27.461 7.605 2.994 1.00 28.51 ? 3 VAL A CG2 1 ATOM 58 N N . LEU A 1 8 ? 25.828 3.982 5.676 1.00 21.61 ? 4 LEU A N 1 ATOM 59 C CA . LEU A 1 8 ? 25.052 3.233 6.695 1.00 22.41 ? 4 LEU A CA 1 ATOM 60 C C . LEU A 1 8 ? 24.593 4.153 7.843 1.00 21.58 ? 4 LEU A C 1 ATOM 61 O O . LEU A 1 8 ? 23.459 4.059 8.274 1.00 20.37 ? 4 LEU A O 1 ATOM 62 C CB . LEU A 1 8 ? 25.811 2.040 7.247 1.00 22.99 ? 4 LEU A CB 1 ATOM 63 C CG . LEU A 1 8 ? 25.036 1.031 8.128 1.00 25.21 ? 4 LEU A CG 1 ATOM 64 C CD1 . LEU A 1 8 ? 25.694 -0.348 8.053 1.00 28.18 ? 4 LEU A CD1 1 ATOM 65 C CD2 . LEU A 1 8 ? 24.923 1.409 9.593 1.00 24.75 ? 4 LEU A CD2 1 ATOM 66 N N . TYR A 1 9 ? 25.449 5.054 8.320 1.00 20.94 ? 5 TYR A N 1 ATOM 67 C CA . TYR A 1 9 ? 24.991 5.844 9.503 1.00 19.78 ? 5 TYR A CA 1 ATOM 68 C C . TYR A 1 9 ? 23.804 6.751 9.177 1.00 19.93 ? 5 TYR A C 1 ATOM 69 O O . TYR A 1 9 ? 23.088 7.171 10.107 1.00 18.79 ? 5 TYR A O 1 ATOM 70 C CB . TYR A 1 9 ? 26.137 6.596 10.198 1.00 18.92 ? 5 TYR A CB 1 ATOM 71 C CG . TYR A 1 9 ? 26.601 7.860 9.510 1.00 18.34 ? 5 TYR A CG 1 ATOM 72 C CD1 . TYR A 1 9 ? 25.980 9.130 9.738 1.00 16.29 ? 5 TYR A CD1 1 ATOM 73 C CD2 . TYR A 1 9 ? 27.727 7.827 8.658 1.00 18.82 ? 5 TYR A CD2 1 ATOM 74 C CE1 . TYR A 1 9 ? 26.437 10.303 9.129 1.00 14.59 ? 5 TYR A CE1 1 ATOM 75 C CE2 . TYR A 1 9 ? 28.201 8.973 8.051 1.00 18.86 ? 5 TYR A CE2 1 ATOM 76 C CZ . TYR A 1 9 ? 27.602 10.219 8.283 1.00 15.37 ? 5 TYR A CZ 1 ATOM 77 O OH . TYR A 1 9 ? 28.081 11.349 7.658 1.00 17.33 ? 5 TYR A OH 1 ATOM 78 N N . LYS A 1 10 ? 23.605 7.089 7.914 1.00 19.62 ? 6 LYS A N 1 ATOM 79 C CA . LYS A 1 10 ? 22.485 7.954 7.526 1.00 20.62 ? 6 LYS A CA 1 ATOM 80 C C . LYS A 1 10 ? 21.176 7.174 7.305 1.00 21.98 ? 6 LYS A C 1 ATOM 81 O O . LYS A 1 10 ? 20.148 7.769 6.994 1.00 24.08 ? 6 LYS A O 1 ATOM 82 C CB . LYS A 1 10 ? 22.849 8.737 6.268 1.00 21.10 ? 6 LYS A CB 1 ATOM 83 C CG . LYS A 1 10 ? 23.904 9.839 6.557 1.00 21.47 ? 6 LYS A CG 1 ATOM 84 C CD . LYS A 1 10 ? 24.261 10.623 5.345 1.00 23.70 ? 6 LYS A CD 1 ATOM 85 C CE . LYS A 1 10 ? 25.344 11.661 5.697 1.00 25.15 ? 6 LYS A CE 1 ATOM 86 N NZ . LYS A 1 10 ? 25.594 12.305 4.406 1.00 33.79 ? 6 LYS A NZ 1 ATOM 87 N N . ASP A 1 11 ? 21.240 5.861 7.458 1.00 21.69 ? 7 ASP A N 1 ATOM 88 C CA . ASP A 1 11 ? 20.102 4.966 7.187 1.00 22.67 ? 7 ASP A CA 1 ATOM 89 C C . ASP A 1 11 ? 19.273 4.778 8.465 1.00 20.76 ? 7 ASP A C 1 ATOM 90 O O . ASP A 1 11 ? 19.691 4.062 9.395 1.00 21.58 ? 7 ASP A O 1 ATOM 91 C CB . ASP A 1 11 ? 20.649 3.606 6.690 1.00 22.82 ? 7 ASP A CB 1 ATOM 92 C CG . ASP A 1 11 ? 19.532 2.625 6.272 1.00 25.33 ? 7 ASP A CG 1 ATOM 93 O OD1 . ASP A 1 11 ? 19.873 1.597 5.643 1.00 26.47 ? 7 ASP A OD1 1 ATOM 94 O OD2 . ASP A 1 11 ? 18.335 2.861 6.549 1.00 26.22 ? 7 ASP A OD2 1 ATOM 95 N N . ALA A 1 12 ? 18.092 5.407 8.482 1.00 22.30 ? 8 ALA A N 1 ATOM 96 C CA . ALA A 1 12 ? 17.224 5.378 9.654 1.00 24.47 ? 8 ALA A CA 1 ATOM 97 C C . ALA A 1 12 ? 16.725 3.968 10.009 1.00 25.44 ? 8 ALA A C 1 ATOM 98 O O . ALA A 1 12 ? 16.306 3.732 11.139 1.00 26.49 ? 8 ALA A O 1 ATOM 99 C CB . ALA A 1 12 ? 16.059 6.325 9.464 1.00 24.26 ? 8 ALA A CB 1 ATOM 100 N N . THR A 1 13 ? 16.783 3.029 9.055 1.00 26.44 ? 9 THR A N 1 ATOM 101 C CA . THR A 1 13 ? 16.352 1.644 9.352 1.00 26.42 ? 9 THR A CA 1 ATOM 102 C C . THR A 1 13 ? 17.374 0.784 10.072 1.00 26.69 ? 9 THR A C 1 ATOM 103 O O . THR A 1 13 ? 17.050 -0.324 10.539 1.00 27.26 ? 9 THR A O 1 ATOM 104 C CB . THR A 1 13 ? 15.912 0.906 8.087 1.00 26.36 ? 9 THR A CB 1 ATOM 105 O OG1 . THR A 1 13 ? 17.067 0.571 7.307 1.00 27.04 ? 9 THR A OG1 1 ATOM 106 C CG2 . THR A 1 13 ? 14.949 1.754 7.255 1.00 25.57 ? 9 THR A CG2 1 ATOM 107 N N . LYS A 1 14 ? 18.624 1.249 10.175 1.00 26.00 ? 10 LYS A N 1 ATOM 108 C CA . LYS A 1 14 ? 19.636 0.456 10.843 1.00 25.20 ? 10 LYS A CA 1 ATOM 109 C C . LYS A 1 14 ? 19.635 0.552 12.374 1.00 25.05 ? 10 LYS A C 1 ATOM 110 O O . LYS A 1 14 ? 19.230 1.591 12.903 1.00 26.18 ? 10 LYS A O 1 ATOM 111 C CB . LYS A 1 14 ? 21.036 0.831 10.313 1.00 25.53 ? 10 LYS A CB 1 ATOM 112 C CG . LYS A 1 14 ? 21.239 0.465 8.850 1.00 26.94 ? 10 LYS A CG 1 ATOM 113 C CD . LYS A 1 14 ? 21.303 -1.034 8.674 1.00 33.28 ? 10 LYS A CD 1 ATOM 114 C CE . LYS A 1 14 ? 21.472 -1.335 7.197 1.00 37.21 ? 10 LYS A CE 1 ATOM 115 N NZ . LYS A 1 14 ? 20.558 -2.457 6.774 1.00 41.84 ? 10 LYS A NZ 1 ATOM 116 N N . PRO A 1 15 ? 20.120 -0.489 13.084 1.00 24.93 ? 11 PRO A N 1 ATOM 117 C CA . PRO A 1 15 ? 20.226 -0.415 14.538 1.00 24.11 ? 11 PRO A CA 1 ATOM 118 C C . PRO A 1 15 ? 21.130 0.715 14.988 1.00 23.47 ? 11 PRO A C 1 ATOM 119 O O . PRO A 1 15 ? 22.156 1.018 14.336 1.00 21.30 ? 11 PRO A O 1 ATOM 120 C CB . PRO A 1 15 ? 20.873 -1.752 14.926 1.00 25.05 ? 11 PRO A CB 1 ATOM 121 C CG . PRO A 1 15 ? 20.454 -2.668 13.845 1.00 25.61 ? 11 PRO A CG 1 ATOM 122 C CD . PRO A 1 15 ? 20.481 -1.839 12.588 1.00 26.01 ? 11 PRO A CD 1 ATOM 123 N N . VAL A 1 16 ? 20.735 1.352 16.086 1.00 21.83 ? 12 VAL A N 1 ATOM 124 C CA . VAL A 1 16 ? 21.516 2.467 16.624 1.00 21.16 ? 12 VAL A CA 1 ATOM 125 C C . VAL A 1 16 ? 22.989 2.101 16.763 1.00 21.10 ? 12 VAL A C 1 ATOM 126 O O . VAL A 1 16 ? 23.829 2.886 16.299 1.00 21.21 ? 12 VAL A O 1 ATOM 127 C CB . VAL A 1 16 ? 20.957 2.925 18.012 1.00 20.60 ? 12 VAL A CB 1 ATOM 128 C CG1 . VAL A 1 16 ? 21.987 3.812 18.804 1.00 20.95 ? 12 VAL A CG1 1 ATOM 129 C CG2 . VAL A 1 16 ? 19.630 3.651 17.810 1.00 23.18 ? 12 VAL A CG2 1 ATOM 130 N N . GLU A 1 17 ? 23.317 0.954 17.386 1.00 21.24 ? 13 GLU A N 1 ATOM 131 C CA . GLU A 1 17 ? 24.743 0.638 17.592 1.00 21.54 ? 13 GLU A CA 1 ATOM 132 C C . GLU A 1 17 ? 25.512 0.524 16.278 1.00 22.59 ? 13 GLU A C 1 ATOM 133 O O . GLU A 1 17 ? 26.698 0.908 16.218 1.00 22.19 ? 13 GLU A O 1 ATOM 134 C CB . GLU A 1 17 ? 24.946 -0.641 18.411 1.00 22.37 ? 13 GLU A CB 1 ATOM 135 C CG . GLU A 1 17 ? 24.505 -0.558 19.854 1.00 23.53 ? 13 GLU A CG 1 ATOM 136 C CD . GLU A 1 17 ? 25.082 0.641 20.600 1.00 28.88 ? 13 GLU A CD 1 ATOM 137 O OE1 . GLU A 1 17 ? 24.258 1.359 21.229 1.00 30.20 ? 13 GLU A OE1 1 ATOM 138 O OE2 . GLU A 1 17 ? 26.331 0.853 20.624 1.00 26.82 ? 13 GLU A OE2 1 ATOM 139 N N . ASP A 1 18 ? 24.856 -0.002 15.242 1.00 22.52 ? 14 ASP A N 1 ATOM 140 C CA . ASP A 1 18 ? 25.503 -0.113 13.921 1.00 23.12 ? 14 ASP A CA 1 ATOM 141 C C . ASP A 1 18 ? 25.755 1.271 13.345 1.00 22.05 ? 14 ASP A C 1 ATOM 142 O O . ASP A 1 18 ? 26.787 1.531 12.705 1.00 20.74 ? 14 ASP A O 1 ATOM 143 C CB . ASP A 1 18 ? 24.667 -0.936 12.948 1.00 23.71 ? 14 ASP A CB 1 ATOM 144 C CG . ASP A 1 18 ? 24.552 -2.407 13.374 1.00 27.19 ? 14 ASP A CG 1 ATOM 145 O OD1 . ASP A 1 18 ? 25.294 -2.860 14.269 1.00 34.44 ? 14 ASP A OD1 1 ATOM 146 O OD2 . ASP A 1 18 ? 23.705 -3.108 12.789 1.00 34.49 ? 14 ASP A OD2 1 ATOM 147 N N . ARG A 1 19 ? 24.791 2.168 13.547 1.00 20.26 ? 15 ARG A N 1 ATOM 148 C CA . ARG A 1 19 ? 24.944 3.542 13.045 1.00 19.23 ? 15 ARG A CA 1 ATOM 149 C C . ARG A 1 19 ? 26.053 4.279 13.779 1.00 18.49 ? 15 ARG A C 1 ATOM 150 O O . ARG A 1 19 ? 26.857 5.010 13.139 1.00 18.69 ? 15 ARG A O 1 ATOM 151 C CB . ARG A 1 19 ? 23.600 4.306 13.167 1.00 18.15 ? 15 ARG A CB 1 ATOM 152 C CG . ARG A 1 19 ? 22.540 3.725 12.265 1.00 17.67 ? 15 ARG A CG 1 ATOM 153 C CD . ARG A 1 19 ? 21.217 4.489 12.456 1.00 19.11 ? 15 ARG A CD 1 ATOM 154 N NE . ARG A 1 19 ? 21.232 5.770 11.755 1.00 18.84 ? 15 ARG A NE 1 ATOM 155 C CZ . ARG A 1 19 ? 20.266 6.682 11.804 1.00 18.53 ? 15 ARG A CZ 1 ATOM 156 N NH1 . ARG A 1 19 ? 19.147 6.443 12.538 1.00 17.87 ? 15 ARG A NH1 1 ATOM 157 N NH2 . ARG A 1 19 ? 20.379 7.789 11.082 1.00 17.45 ? 15 ARG A NH2 1 ATOM 158 N N . VAL A 1 20 ? 26.118 4.094 15.098 1.00 18.43 ? 16 VAL A N 1 ATOM 159 C CA . VAL A 1 20 ? 27.181 4.695 15.927 1.00 18.49 ? 16 VAL A CA 1 ATOM 160 C C . VAL A 1 20 ? 28.562 4.235 15.446 1.00 19.16 ? 16 VAL A C 1 ATOM 161 O O . VAL A 1 20 ? 29.459 5.070 15.216 1.00 18.67 ? 16 VAL A O 1 ATOM 162 C CB . VAL A 1 20 ? 27.032 4.335 17.433 1.00 18.16 ? 16 VAL A CB 1 ATOM 163 C CG1 . VAL A 1 20 ? 28.228 4.797 18.233 1.00 19.29 ? 16 VAL A CG1 1 ATOM 164 C CG2 . VAL A 1 20 ? 25.742 4.983 18.025 1.00 20.74 ? 16 VAL A CG2 1 ATOM 165 N N . ALA A 1 21 ? 28.726 2.918 15.293 1.00 20.80 ? 17 ALA A N 1 ATOM 166 C CA . ALA A 1 21 ? 30.035 2.376 14.896 1.00 21.54 ? 17 ALA A CA 1 ATOM 167 C C . ALA A 1 21 ? 30.408 2.834 13.498 1.00 20.42 ? 17 ALA A C 1 ATOM 168 O O . ALA A 1 21 ? 31.579 3.165 13.246 1.00 20.19 ? 17 ALA A O 1 ATOM 169 C CB . ALA A 1 21 ? 30.035 0.889 14.993 1.00 22.33 ? 17 ALA A CB 1 ATOM 170 N N . ASP A 1 22 ? 29.442 2.912 12.598 1.00 20.27 ? 18 ASP A N 1 ATOM 171 C CA . ASP A 1 22 ? 29.720 3.274 11.203 1.00 20.29 ? 18 ASP A CA 1 ATOM 172 C C . ASP A 1 22 ? 30.181 4.728 11.122 1.00 20.46 ? 18 ASP A C 1 ATOM 173 O O . ASP A 1 22 ? 31.109 5.072 10.393 1.00 20.80 ? 18 ASP A O 1 ATOM 174 C CB . ASP A 1 22 ? 28.502 3.087 10.326 1.00 21.74 ? 18 ASP A CB 1 ATOM 175 C CG . ASP A 1 22 ? 28.797 3.402 8.890 1.00 22.99 ? 18 ASP A CG 1 ATOM 176 O OD1 . ASP A 1 22 ? 29.457 2.550 8.214 1.00 25.94 ? 18 ASP A OD1 1 ATOM 177 O OD2 . ASP A 1 22 ? 28.399 4.462 8.402 1.00 21.60 ? 18 ASP A OD2 1 ATOM 178 N N . LEU A 1 23 ? 29.501 5.606 11.867 1.00 18.97 ? 19 LEU A N 1 ATOM 179 C CA . LEU A 1 23 ? 29.885 6.995 11.880 1.00 17.53 ? 19 LEU A CA 1 ATOM 180 C C . LEU A 1 23 ? 31.243 7.188 12.588 1.00 17.85 ? 19 LEU A C 1 ATOM 181 O O . LEU A 1 23 ? 32.119 7.889 12.057 1.00 17.92 ? 19 LEU A O 1 ATOM 182 C CB . LEU A 1 23 ? 28.770 7.837 12.526 1.00 17.43 ? 19 LEU A CB 1 ATOM 183 C CG . LEU A 1 23 ? 29.078 9.309 12.707 1.00 14.68 ? 19 LEU A CG 1 ATOM 184 C CD1 . LEU A 1 23 ? 29.569 10.051 11.392 1.00 16.04 ? 19 LEU A CD1 1 ATOM 185 C CD2 . LEU A 1 23 ? 27.811 10.053 13.280 1.00 17.85 ? 19 LEU A CD2 1 ATOM 186 N N . LEU A 1 24 ? 31.411 6.550 13.748 1.00 18.10 ? 20 LEU A N 1 ATOM 187 C CA . LEU A 1 24 ? 32.628 6.723 14.533 1.00 18.05 ? 20 LEU A CA 1 ATOM 188 C C . LEU A 1 24 ? 33.863 6.347 13.678 1.00 19.13 ? 20 LEU A C 1 ATOM 189 O O . LEU A 1 24 ? 34.892 7.060 13.717 1.00 19.02 ? 20 LEU A O 1 ATOM 190 C CB . LEU A 1 24 ? 32.578 5.884 15.807 1.00 18.53 ? 20 LEU A CB 1 ATOM 191 C CG . LEU A 1 24 ? 33.809 6.007 16.711 1.00 19.08 ? 20 LEU A CG 1 ATOM 192 C CD1 . LEU A 1 24 ? 33.844 7.388 17.384 1.00 20.01 ? 20 LEU A CD1 1 ATOM 193 C CD2 . LEU A 1 24 ? 33.786 4.863 17.732 1.00 20.87 ? 20 LEU A CD2 1 ATOM 194 N N . GLY A 1 25 ? 33.691 5.275 12.889 1.00 19.43 ? 21 GLY A N 1 ATOM 195 C CA . GLY A 1 25 ? 34.836 4.748 12.101 1.00 20.21 ? 21 GLY A CA 1 ATOM 196 C C . GLY A 1 25 ? 35.267 5.724 11.014 1.00 21.43 ? 21 GLY A C 1 ATOM 197 O O . GLY A 1 25 ? 36.379 5.595 10.473 1.00 22.71 ? 21 GLY A O 1 ATOM 198 N N . ARG A 1 26 ? 34.422 6.699 10.682 1.00 20.41 ? 22 ARG A N 1 ATOM 199 C CA . ARG A 1 26 ? 34.719 7.647 9.614 1.00 19.04 ? 22 ARG A CA 1 ATOM 200 C C . ARG A 1 26 ? 35.318 8.942 10.131 1.00 18.46 ? 22 ARG A C 1 ATOM 201 O O . ARG A 1 26 ? 35.731 9.787 9.339 1.00 20.00 ? 22 ARG A O 1 ATOM 202 C CB . ARG A 1 26 ? 33.430 7.990 8.840 1.00 19.38 ? 22 ARG A CB 1 ATOM 203 C CG . ARG A 1 26 ? 32.767 6.793 8.207 1.00 21.00 ? 22 ARG A CG 1 ATOM 204 C CD . ARG A 1 26 ? 31.430 7.215 7.629 1.00 20.28 ? 22 ARG A CD 1 ATOM 205 N NE . ARG A 1 26 ? 30.614 6.076 7.237 1.00 22.66 ? 22 ARG A NE 1 ATOM 206 C CZ . ARG A 1 26 ? 30.479 5.678 5.982 1.00 28.22 ? 22 ARG A CZ 1 ATOM 207 N NH1 . ARG A 1 26 ? 31.146 6.313 5.012 1.00 28.32 ? 22 ARG A NH1 1 ATOM 208 N NH2 . ARG A 1 26 ? 29.684 4.647 5.703 1.00 28.36 ? 22 ARG A NH2 1 ATOM 209 N N . MET A 1 27 ? 35.293 9.156 11.449 1.00 17.97 ? 23 MET A N 1 ATOM 210 C CA . MET A 1 27 ? 35.567 10.489 11.986 1.00 17.93 ? 23 MET A CA 1 ATOM 211 C C . MET A 1 27 ? 37.060 10.792 12.221 1.00 17.16 ? 23 MET A C 1 ATOM 212 O O . MET A 1 27 ? 37.785 9.935 12.737 1.00 20.25 ? 23 MET A O 1 ATOM 213 C CB . MET A 1 27 ? 34.828 10.656 13.331 1.00 17.77 ? 23 MET A CB 1 ATOM 214 C CG . MET A 1 27 ? 33.317 10.691 13.099 1.00 17.80 ? 23 MET A CG 1 ATOM 215 S SD . MET A 1 27 ? 32.430 10.670 14.696 1.00 18.83 ? 23 MET A SD 1 ATOM 216 C CE . MET A 1 27 ? 32.614 12.320 15.210 1.00 17.37 ? 23 MET A CE 1 ATOM 217 N N . THR A 1 28 ? 37.465 12.007 11.872 1.00 18.64 ? 24 THR A N 1 ATOM 218 C CA . THR A 1 28 ? 38.818 12.482 12.231 1.00 18.46 ? 24 THR A CA 1 ATOM 219 C C . THR A 1 28 ? 38.860 12.842 13.720 1.00 19.19 ? 24 THR A C 1 ATOM 220 O O . THR A 1 28 ? 37.794 12.962 14.393 1.00 18.74 ? 24 THR A O 1 ATOM 221 C CB . THR A 1 28 ? 39.182 13.728 11.446 1.00 18.65 ? 24 THR A CB 1 ATOM 222 O OG1 . THR A 1 28 ? 38.361 14.825 11.846 1.00 18.33 ? 24 THR A OG1 1 ATOM 223 C CG2 . THR A 1 28 ? 39.075 13.503 9.898 1.00 18.46 ? 24 THR A CG2 1 ATOM 224 N N . LEU A 1 29 ? 40.057 13.051 14.245 1.00 18.97 ? 25 LEU A N 1 ATOM 225 C CA . LEU A 1 29 ? 40.196 13.423 15.649 1.00 19.24 ? 25 LEU A CA 1 ATOM 226 C C . LEU A 1 29 ? 39.480 14.781 15.887 1.00 18.53 ? 25 LEU A C 1 ATOM 227 O O . LEU A 1 29 ? 38.790 14.947 16.923 1.00 18.09 ? 25 LEU A O 1 ATOM 228 C CB . LEU A 1 29 ? 41.692 13.492 16.022 1.00 19.30 ? 25 LEU A CB 1 ATOM 229 C CG . LEU A 1 29 ? 41.876 13.954 17.498 1.00 20.53 ? 25 LEU A CG 1 ATOM 230 C CD1 . LEU A 1 29 ? 41.148 13.058 18.480 1.00 23.67 ? 25 LEU A CD1 1 ATOM 231 C CD2 . LEU A 1 29 ? 43.395 13.979 17.815 1.00 23.66 ? 25 LEU A CD2 1 ATOM 232 N N . ALA A 1 30 ? 39.584 15.707 14.934 1.00 17.81 ? 26 ALA A N 1 ATOM 233 C CA . ALA A 1 30 ? 38.960 17.010 15.006 1.00 16.59 ? 26 ALA A CA 1 ATOM 234 C C . ALA A 1 30 ? 37.428 16.825 15.105 1.00 17.79 ? 26 ALA A C 1 ATOM 235 O O . ALA A 1 30 ? 36.734 17.490 15.898 1.00 17.26 ? 26 ALA A O 1 ATOM 236 C CB . ALA A 1 30 ? 39.311 17.850 13.778 1.00 18.92 ? 26 ALA A CB 1 ATOM 237 N N . GLU A 1 31 ? 36.905 15.894 14.315 1.00 17.14 ? 27 GLU A N 1 ATOM 238 C CA . GLU A 1 31 ? 35.433 15.677 14.312 1.00 17.15 ? 27 GLU A CA 1 ATOM 239 C C . GLU A 1 31 ? 34.988 15.049 15.631 1.00 16.61 ? 27 GLU A C 1 ATOM 240 O O . GLU A 1 31 ? 33.887 15.388 16.174 1.00 16.63 ? 27 GLU A O 1 ATOM 241 C CB . GLU A 1 31 ? 35.039 14.790 13.108 1.00 15.80 ? 27 GLU A CB 1 ATOM 242 C CG . GLU A 1 31 ? 35.059 15.642 11.803 1.00 18.18 ? 27 GLU A CG 1 ATOM 243 C CD . GLU A 1 31 ? 35.089 14.799 10.519 1.00 15.95 ? 27 GLU A CD 1 ATOM 244 O OE1 . GLU A 1 31 ? 35.509 13.618 10.544 1.00 17.55 ? 27 GLU A OE1 1 ATOM 245 O OE2 . GLU A 1 31 ? 34.679 15.390 9.494 1.00 18.86 ? 27 GLU A OE2 1 ATOM 246 N N . LYS A 1 32 ? 35.808 14.131 16.153 1.00 16.81 ? 28 LYS A N 1 ATOM 247 C CA . LYS A 1 32 ? 35.542 13.467 17.450 1.00 16.17 ? 28 LYS A CA 1 ATOM 248 C C . LYS A 1 32 ? 35.550 14.501 18.593 1.00 16.73 ? 28 LYS A C 1 ATOM 249 O O . LYS A 1 32 ? 34.616 14.545 19.425 1.00 16.09 ? 28 LYS A O 1 ATOM 250 C CB . LYS A 1 32 ? 36.559 12.331 17.697 1.00 16.66 ? 28 LYS A CB 1 ATOM 251 C CG . LYS A 1 32 ? 36.348 11.164 16.748 1.00 18.58 ? 28 LYS A CG 1 ATOM 252 C CD . LYS A 1 32 ? 37.395 10.084 17.096 1.00 18.32 ? 28 LYS A CD 1 ATOM 253 C CE . LYS A 1 32 ? 37.200 8.940 16.143 1.00 21.79 ? 28 LYS A CE 1 ATOM 254 N NZ . LYS A 1 32 ? 38.335 7.948 16.246 1.00 20.64 ? 28 LYS A NZ 1 ATOM 255 N N . ILE A 1 33 ? 36.613 15.300 18.692 1.00 16.46 ? 29 ILE A N 1 ATOM 256 C CA . ILE A 1 33 ? 36.726 16.286 19.790 1.00 16.89 ? 29 ILE A CA 1 ATOM 257 C C . ILE A 1 33 ? 35.637 17.339 19.673 1.00 17.52 ? 29 ILE A C 1 ATOM 258 O O . ILE A 1 33 ? 35.063 17.798 20.688 1.00 17.02 ? 29 ILE A O 1 ATOM 259 C CB . ILE A 1 33 ? 38.180 16.875 19.877 1.00 17.88 ? 29 ILE A CB 1 ATOM 260 C CG1 . ILE A 1 33 ? 39.073 15.780 20.413 1.00 19.96 ? 29 ILE A CG1 1 ATOM 261 C CG2 . ILE A 1 33 ? 38.238 18.141 20.697 1.00 19.71 ? 29 ILE A CG2 1 ATOM 262 C CD1 . ILE A 1 33 ? 40.550 16.090 20.257 1.00 22.67 ? 29 ILE A CD1 1 ATOM 263 N N . GLY A 1 34 ? 35.292 17.711 18.440 1.00 16.11 ? 30 GLY A N 1 ATOM 264 C CA . GLY A 1 34 ? 34.134 18.588 18.247 1.00 14.74 ? 30 GLY A CA 1 ATOM 265 C C . GLY A 1 34 ? 32.862 18.035 18.893 1.00 14.87 ? 30 GLY A C 1 ATOM 266 O O . GLY A 1 34 ? 32.127 18.828 19.527 1.00 14.65 ? 30 GLY A O 1 ATOM 267 N N . GLN A 1 35 ? 32.582 16.754 18.726 1.00 14.70 ? 31 GLN A N 1 ATOM 268 C CA . GLN A 1 35 ? 31.323 16.190 19.327 1.00 15.10 ? 31 GLN A CA 1 ATOM 269 C C . GLN A 1 35 ? 31.321 16.348 20.830 1.00 15.56 ? 31 GLN A C 1 ATOM 270 O O . GLN A 1 35 ? 30.251 16.512 21.451 1.00 15.31 ? 31 GLN A O 1 ATOM 271 C CB . GLN A 1 35 ? 31.179 14.712 19.013 1.00 15.41 ? 31 GLN A CB 1 ATOM 272 C CG . GLN A 1 35 ? 30.672 14.474 17.621 1.00 15.25 ? 31 GLN A CG 1 ATOM 273 C CD . GLN A 1 35 ? 29.360 15.138 17.353 1.00 15.90 ? 31 GLN A CD 1 ATOM 274 O OE1 . GLN A 1 35 ? 28.344 14.801 18.004 1.00 16.83 ? 31 GLN A OE1 1 ATOM 275 N NE2 . GLN A 1 35 ? 29.350 16.061 16.431 1.00 14.87 ? 31 GLN A NE2 1 ATOM 276 N N . MET A 1 36 ? 32.495 16.280 21.455 1.00 14.25 ? 32 MET A N 1 ATOM 277 C CA . MET A 1 36 ? 32.681 16.393 22.903 1.00 14.92 ? 32 MET A CA 1 ATOM 278 C C . MET A 1 36 ? 32.588 17.827 23.432 1.00 14.66 ? 32 MET A C 1 ATOM 279 O O . MET A 1 36 ? 32.714 18.046 24.660 1.00 15.95 ? 32 MET A O 1 ATOM 280 C CB . MET A 1 36 ? 34.075 15.838 23.281 1.00 15.18 ? 32 MET A CB 1 ATOM 281 C CG . MET A 1 36 ? 34.154 14.357 22.945 1.00 14.98 ? 32 MET A CG 1 ATOM 282 S SD . MET A 1 36 ? 35.875 13.738 23.209 1.00 18.10 ? 32 MET A SD 1 ATOM 283 C CE . MET A 1 36 ? 35.996 13.869 24.985 1.00 18.99 ? 32 MET A CE 1 ATOM 284 N N . THR A 1 37 ? 32.421 18.813 22.527 1.00 14.12 ? 33 THR A N 1 ATOM 285 C CA . THR A 1 37 ? 32.470 20.246 22.874 1.00 14.17 ? 33 THR A CA 1 ATOM 286 C C . THR A 1 37 ? 31.037 20.835 22.830 1.00 14.08 ? 33 THR A C 1 ATOM 287 O O . THR A 1 37 ? 30.408 20.817 21.762 1.00 14.71 ? 33 THR A O 1 ATOM 288 C CB . THR A 1 37 ? 33.364 21.031 21.880 1.00 15.30 ? 33 THR A CB 1 ATOM 289 O OG1 . THR A 1 37 ? 34.660 20.407 21.850 1.00 17.00 ? 33 THR A OG1 1 ATOM 290 C CG2 . THR A 1 37 ? 33.545 22.481 22.281 1.00 14.27 ? 33 THR A CG2 1 ATOM 291 N N . GLN A 1 38 ? 30.573 21.363 23.989 1.00 13.36 ? 34 GLN A N 1 ATOM 292 C CA . GLN A 1 38 ? 29.293 22.098 24.058 1.00 12.65 ? 34 GLN A CA 1 ATOM 293 C C . GLN A 1 38 ? 29.621 23.550 24.291 1.00 13.62 ? 34 GLN A C 1 ATOM 294 O O . GLN A 1 38 ? 30.406 23.869 25.203 1.00 14.16 ? 34 GLN A O 1 ATOM 295 C CB . GLN A 1 38 ? 28.461 21.559 25.197 1.00 12.83 ? 34 GLN A CB 1 ATOM 296 C CG . GLN A 1 38 ? 27.091 22.329 25.265 1.00 13.26 ? 34 GLN A CG 1 ATOM 297 C CD . GLN A 1 38 ? 26.265 21.819 26.420 1.00 14.12 ? 34 GLN A CD 1 ATOM 298 O OE1 . GLN A 1 38 ? 26.516 22.163 27.572 1.00 15.31 ? 34 GLN A OE1 1 ATOM 299 N NE2 . GLN A 1 38 ? 25.262 21.002 26.104 1.00 14.11 ? 34 GLN A NE2 1 ATOM 300 N N . ILE A 1 39 ? 29.074 24.441 23.457 1.00 13.69 ? 35 ILE A N 1 ATOM 301 C CA . ILE A 1 39 ? 29.328 25.871 23.583 1.00 13.95 ? 35 ILE A CA 1 ATOM 302 C C . ILE A 1 39 ? 28.046 26.706 23.810 1.00 14.46 ? 35 ILE A C 1 ATOM 303 O O . ILE A 1 39 ? 26.942 26.283 23.417 1.00 14.97 ? 35 ILE A O 1 ATOM 304 C CB . ILE A 1 39 ? 30.107 26.448 22.396 1.00 14.57 ? 35 ILE A CB 1 ATOM 305 C CG1 . ILE A 1 39 ? 29.230 26.544 21.109 1.00 14.85 ? 35 ILE A CG1 1 ATOM 306 C CG2 . ILE A 1 39 ? 31.295 25.576 22.158 1.00 15.87 ? 35 ILE A CG2 1 ATOM 307 C CD1 . ILE A 1 39 ? 30.015 27.187 19.897 1.00 14.83 ? 35 ILE A CD1 1 ATOM 308 N N . GLU A 1 40 ? 28.204 27.876 24.430 1.00 13.86 ? 36 GLU A N 1 ATOM 309 C CA . GLU A 1 40 ? 27.078 28.803 24.597 1.00 13.37 ? 36 GLU A CA 1 ATOM 310 C C . GLU A 1 40 ? 26.645 29.357 23.253 1.00 15.22 ? 36 GLU A C 1 ATOM 311 O O . GLU A 1 40 ? 27.461 29.663 22.369 1.00 13.93 ? 36 GLU A O 1 ATOM 312 C CB . GLU A 1 40 ? 27.506 29.983 25.463 1.00 12.89 ? 36 GLU A CB 1 ATOM 313 C CG . GLU A 1 40 ? 26.746 30.111 26.786 1.00 14.01 ? 36 GLU A CG 1 ATOM 314 C CD . GLU A 1 40 ? 25.341 30.654 26.643 1.00 14.88 ? 36 GLU A CD 1 ATOM 315 O OE1 . GLU A 1 40 ? 24.934 31.187 25.586 1.00 14.74 ? 36 GLU A OE1 1 ATOM 316 O OE2 . GLU A 1 40 ? 24.641 30.633 27.705 1.00 15.62 ? 36 GLU A OE2 1 ATOM 317 N N . ARG A 1 41 ? 25.345 29.490 23.060 1.00 13.61 ? 37 ARG A N 1 ATOM 318 C CA . ARG A 1 41 ? 24.872 30.243 21.885 1.00 13.83 ? 37 ARG A CA 1 ATOM 319 C C . ARG A 1 41 ? 25.505 31.629 21.839 1.00 14.61 ? 37 ARG A C 1 ATOM 320 O O . ARG A 1 41 ? 25.662 32.155 20.737 1.00 15.68 ? 37 ARG A O 1 ATOM 321 C CB . ARG A 1 41 ? 23.347 30.399 21.868 1.00 13.56 ? 37 ARG A CB 1 ATOM 322 C CG . ARG A 1 41 ? 22.784 30.990 23.164 1.00 12.91 ? 37 ARG A CG 1 ATOM 323 C CD . ARG A 1 41 ? 21.373 31.614 22.858 1.00 12.96 ? 37 ARG A CD 1 ATOM 324 N NE . ARG A 1 41 ? 21.448 32.877 22.057 1.00 13.15 ? 37 ARG A NE 1 ATOM 325 C CZ . ARG A 1 41 ? 21.626 34.079 22.582 1.00 13.95 ? 37 ARG A CZ 1 ATOM 326 N NH1 . ARG A 1 41 ? 21.791 34.250 23.901 1.00 14.48 ? 37 ARG A NH1 1 ATOM 327 N NH2 . ARG A 1 41 ? 21.625 35.159 21.772 1.00 14.94 ? 37 ARG A NH2 1 ATOM 328 N N . LEU A 1 42 ? 25.883 32.183 22.996 1.00 14.56 ? 38 LEU A N 1 ATOM 329 C CA . LEU A 1 42 ? 26.473 33.547 22.973 1.00 15.79 ? 38 LEU A CA 1 ATOM 330 C C . LEU A 1 42 ? 27.786 33.586 22.178 1.00 16.66 ? 38 LEU A C 1 ATOM 331 O O . LEU A 1 42 ? 28.128 34.682 21.679 1.00 18.48 ? 38 LEU A O 1 ATOM 332 C CB . LEU A 1 42 ? 26.670 34.098 24.385 1.00 15.08 ? 38 LEU A CB 1 ATOM 333 C CG . LEU A 1 42 ? 25.337 34.496 25.051 1.00 18.09 ? 38 LEU A CG 1 ATOM 334 C CD1 . LEU A 1 42 ? 25.590 34.516 26.557 1.00 20.48 ? 38 LEU A CD1 1 ATOM 335 C CD2 . LEU A 1 42 ? 24.821 35.805 24.529 1.00 19.90 ? 38 LEU A CD2 1 ATOM 336 N N . VAL A 1 43 ? 28.491 32.483 22.083 1.00 15.65 ? 39 VAL A N 1 ATOM 337 C CA . VAL A 1 43 ? 29.775 32.459 21.317 1.00 16.63 ? 39 VAL A CA 1 ATOM 338 C C . VAL A 1 43 ? 29.649 31.697 20.003 1.00 17.25 ? 39 VAL A C 1 ATOM 339 O O . VAL A 1 43 ? 30.665 31.553 19.272 1.00 18.98 ? 39 VAL A O 1 ATOM 340 C CB . VAL A 1 43 ? 30.948 31.879 22.192 1.00 16.02 ? 39 VAL A CB 1 ATOM 341 C CG1 . VAL A 1 43 ? 31.154 32.729 23.449 1.00 18.31 ? 39 VAL A CG1 1 ATOM 342 C CG2 . VAL A 1 43 ? 30.743 30.342 22.516 1.00 16.80 ? 39 VAL A CG2 1 ATOM 343 N N . ALA A 1 44 ? 28.450 31.203 19.656 1.00 15.94 ? 40 ALA A N 1 ATOM 344 C CA . ALA A 1 44 ? 28.313 30.411 18.454 1.00 16.16 ? 40 ALA A CA 1 ATOM 345 C C . ALA A 1 44 ? 28.023 31.291 17.246 1.00 17.55 ? 40 ALA A C 1 ATOM 346 O O . ALA A 1 44 ? 27.327 32.299 17.329 1.00 18.87 ? 40 ALA A O 1 ATOM 347 C CB . ALA A 1 44 ? 27.147 29.421 18.588 1.00 16.19 ? 40 ALA A CB 1 ATOM 348 N N . THR A 1 45 ? 28.567 30.881 16.106 1.00 18.34 ? 41 THR A N 1 ATOM 349 C CA . THR A 1 45 ? 28.220 31.465 14.791 1.00 17.95 ? 41 THR A CA 1 ATOM 350 C C . THR A 1 45 ? 28.278 30.307 13.812 1.00 18.84 ? 41 THR A C 1 ATOM 351 O O . THR A 1 45 ? 28.828 29.242 14.121 1.00 17.86 ? 41 THR A O 1 ATOM 352 C CB . THR A 1 45 ? 29.284 32.510 14.316 1.00 18.35 ? 41 THR A CB 1 ATOM 353 O OG1 . THR A 1 45 ? 30.475 31.818 13.954 1.00 19.39 ? 41 THR A OG1 1 ATOM 354 C CG2 . THR A 1 45 ? 29.623 33.559 15.358 1.00 20.64 ? 41 THR A CG2 1 ATOM 355 N N . PRO A 1 46 ? 27.684 30.487 12.623 1.00 19.34 ? 42 PRO A N 1 ATOM 356 C CA . PRO A 1 46 ? 27.736 29.380 11.650 1.00 20.10 ? 42 PRO A CA 1 ATOM 357 C C . PRO A 1 46 ? 29.183 28.918 11.368 1.00 19.64 ? 42 PRO A C 1 ATOM 358 O O . PRO A 1 46 ? 29.473 27.725 11.364 1.00 17.87 ? 42 PRO A O 1 ATOM 359 C CB . PRO A 1 46 ? 27.072 29.983 10.398 1.00 20.87 ? 42 PRO A CB 1 ATOM 360 C CG . PRO A 1 46 ? 26.127 31.036 10.950 1.00 23.12 ? 42 PRO A CG 1 ATOM 361 C CD . PRO A 1 46 ? 26.892 31.649 12.157 1.00 20.25 ? 42 PRO A CD 1 ATOM 362 N N . ASP A 1 47 ? 30.109 29.853 11.152 1.00 20.84 ? 43 ASP A N 1 ATOM 363 C CA . ASP A 1 47 ? 31.476 29.443 10.901 1.00 21.38 ? 43 ASP A CA 1 ATOM 364 C C . ASP A 1 47 ? 32.128 28.695 12.076 1.00 19.56 ? 43 ASP A C 1 ATOM 365 O O . ASP A 1 47 ? 32.828 27.712 11.893 1.00 19.92 ? 43 ASP A O 1 ATOM 366 C CB . ASP A 1 47 ? 32.332 30.634 10.470 1.00 23.20 ? 43 ASP A CB 1 ATOM 367 C CG . ASP A 1 47 ? 31.975 31.117 9.047 1.00 29.28 ? 43 ASP A CG 1 ATOM 368 O OD1 . ASP A 1 47 ? 31.680 30.274 8.192 1.00 34.16 ? 43 ASP A OD1 1 ATOM 369 O OD2 . ASP A 1 47 ? 31.895 32.339 8.806 1.00 36.93 ? 43 ASP A OD2 1 ATOM 370 N N . VAL A 1 48 ? 31.881 29.173 13.305 1.00 17.72 ? 44 VAL A N 1 ATOM 371 C CA . VAL A 1 48 ? 32.453 28.512 14.466 1.00 16.83 ? 44 VAL A CA 1 ATOM 372 C C . VAL A 1 48 ? 31.934 27.068 14.562 1.00 16.38 ? 44 VAL A C 1 ATOM 373 O O . VAL A 1 48 ? 32.651 26.128 14.834 1.00 16.24 ? 44 VAL A O 1 ATOM 374 C CB . VAL A 1 48 ? 32.107 29.318 15.744 1.00 16.59 ? 44 VAL A CB 1 ATOM 375 C CG1 . VAL A 1 48 ? 32.393 28.471 16.989 1.00 16.64 ? 44 VAL A CG1 1 ATOM 376 C CG2 . VAL A 1 48 ? 32.898 30.655 15.780 1.00 17.14 ? 44 VAL A CG2 1 ATOM 377 N N . LEU A 1 49 ? 30.615 26.890 14.351 1.00 16.24 ? 45 LEU A N 1 ATOM 378 C CA . LEU A 1 49 ? 30.055 25.554 14.434 1.00 16.71 ? 45 LEU A CA 1 ATOM 379 C C . LEU A 1 49 ? 30.565 24.539 13.413 1.00 16.55 ? 45 LEU A C 1 ATOM 380 O O . LEU A 1 49 ? 30.774 23.354 13.724 1.00 16.86 ? 45 LEU A O 1 ATOM 381 C CB . LEU A 1 49 ? 28.514 25.657 14.356 1.00 15.86 ? 45 LEU A CB 1 ATOM 382 C CG . LEU A 1 49 ? 27.887 26.377 15.550 1.00 17.04 ? 45 LEU A CG 1 ATOM 383 C CD1 . LEU A 1 49 ? 26.364 26.625 15.287 1.00 17.39 ? 45 LEU A CD1 1 ATOM 384 C CD2 . LEU A 1 49 ? 28.064 25.536 16.856 1.00 16.72 ? 45 LEU A CD2 1 ATOM 385 N N . ARG A 1 50 ? 30.744 25.023 12.180 1.00 17.76 ? 46 ARG A N 1 ATOM 386 C CA . ARG A 1 50 ? 31.246 24.197 11.089 1.00 20.06 ? 46 ARG A CA 1 ATOM 387 C C . ARG A 1 50 ? 32.749 23.955 11.299 1.00 18.81 ? 46 ARG A C 1 ATOM 388 O O . ARG A 1 50 ? 33.239 22.827 11.248 1.00 19.81 ? 46 ARG A O 1 ATOM 389 C CB . ARG A 1 50 ? 31.004 24.972 9.784 1.00 21.79 ? 46 ARG A CB 1 ATOM 390 C CG . ARG A 1 50 ? 31.354 24.313 8.488 1.00 29.94 ? 46 ARG A CG 1 ATOM 391 C CD . ARG A 1 50 ? 31.059 25.315 7.341 1.00 33.39 ? 46 ARG A CD 1 ATOM 392 N NE . ARG A 1 50 ? 29.648 25.679 7.379 1.00 38.53 ? 46 ARG A NE 1 ATOM 393 C CZ . ARG A 1 50 ? 29.122 26.911 7.488 1.00 39.89 ? 46 ARG A CZ 1 ATOM 394 N NH1 . ARG A 1 50 ? 27.796 27.039 7.484 1.00 37.38 ? 46 ARG A NH1 1 ATOM 395 N NH2 . ARG A 1 50 ? 29.870 28.013 7.582 1.00 43.99 ? 46 ARG A NH2 1 ATOM 396 N N . ASP A 1 51 ? 33.487 25.032 11.535 1.00 19.13 ? 47 ASP A N 1 ATOM 397 C CA . ASP A 1 51 ? 34.954 24.918 11.515 1.00 18.65 ? 47 ASP A CA 1 ATOM 398 C C . ASP A 1 51 ? 35.488 24.061 12.649 1.00 18.78 ? 47 ASP A C 1 ATOM 399 O O . ASP A 1 51 ? 36.526 23.404 12.519 1.00 20.77 ? 47 ASP A O 1 ATOM 400 C CB . ASP A 1 51 ? 35.592 26.303 11.576 1.00 18.93 ? 47 ASP A CB 1 ATOM 401 C CG . ASP A 1 51 ? 35.397 27.114 10.300 1.00 21.82 ? 47 ASP A CG 1 ATOM 402 O OD1 . ASP A 1 51 ? 35.672 28.335 10.363 1.00 25.16 ? 47 ASP A OD1 1 ATOM 403 O OD2 . ASP A 1 51 ? 34.914 26.591 9.272 1.00 24.40 ? 47 ASP A OD2 1 ATOM 404 N N . ASN A 1 52 ? 34.793 24.066 13.802 1.00 17.09 ? 48 ASN A N 1 ATOM 405 C CA . ASN A 1 52 ? 35.172 23.277 14.962 1.00 17.39 ? 48 ASN A CA 1 ATOM 406 C C . ASN A 1 52 ? 34.345 22.012 15.164 1.00 16.69 ? 48 ASN A C 1 ATOM 407 O O . ASN A 1 52 ? 34.533 21.313 16.179 1.00 16.19 ? 48 ASN A O 1 ATOM 408 C CB . ASN A 1 52 ? 35.096 24.148 16.207 1.00 16.52 ? 48 ASN A CB 1 ATOM 409 C CG . ASN A 1 52 ? 36.003 25.388 16.075 1.00 19.27 ? 48 ASN A CG 1 ATOM 410 O OD1 . ASN A 1 52 ? 37.216 25.279 16.312 1.00 20.79 ? 48 ASN A OD1 1 ATOM 411 N ND2 . ASN A 1 52 ? 35.447 26.529 15.673 1.00 19.06 ? 48 ASN A ND2 1 ATOM 412 N N . PHE A 1 53 ? 33.453 21.714 14.195 1.00 16.84 ? 49 PHE A N 1 ATOM 413 C CA . PHE A 1 53 ? 32.694 20.426 14.209 1.00 15.51 ? 49 PHE A CA 1 ATOM 414 C C . PHE A 1 53 ? 31.944 20.266 15.560 1.00 15.38 ? 49 PHE A C 1 ATOM 415 O O . PHE A 1 53 ? 31.912 19.184 16.149 1.00 16.05 ? 49 PHE A O 1 ATOM 416 C CB . PHE A 1 53 ? 33.638 19.216 13.982 1.00 16.23 ? 49 PHE A CB 1 ATOM 417 C CG . PHE A 1 53 ? 34.428 19.317 12.694 1.00 16.50 ? 49 PHE A CG 1 ATOM 418 C CD1 . PHE A 1 53 ? 33.820 19.056 11.485 1.00 17.01 ? 49 PHE A CD1 1 ATOM 419 C CD2 . PHE A 1 53 ? 35.777 19.705 12.731 1.00 19.83 ? 49 PHE A CD2 1 ATOM 420 C CE1 . PHE A 1 53 ? 34.573 19.164 10.232 1.00 19.03 ? 49 PHE A CE1 1 ATOM 421 C CE2 . PHE A 1 53 ? 36.535 19.817 11.526 1.00 19.27 ? 49 PHE A CE2 1 ATOM 422 C CZ . PHE A 1 53 ? 35.919 19.536 10.294 1.00 18.62 ? 49 PHE A CZ 1 ATOM 423 N N . ILE A 1 54 ? 31.361 21.372 16.022 1.00 15.17 ? 50 ILE A N 1 ATOM 424 C CA . ILE A 1 54 ? 30.787 21.455 17.402 1.00 14.26 ? 50 ILE A CA 1 ATOM 425 C C . ILE A 1 54 ? 29.632 20.433 17.561 1.00 14.82 ? 50 ILE A C 1 ATOM 426 O O . ILE A 1 54 ? 28.772 20.302 16.644 1.00 15.27 ? 50 ILE A O 1 ATOM 427 C CB . ILE A 1 54 ? 30.279 22.871 17.684 1.00 14.50 ? 50 ILE A CB 1 ATOM 428 C CG1 . ILE A 1 54 ? 31.454 23.864 17.759 1.00 15.35 ? 50 ILE A CG1 1 ATOM 429 C CG2 . ILE A 1 54 ? 29.503 22.959 18.996 1.00 13.78 ? 50 ILE A CG2 1 ATOM 430 C CD1 . ILE A 1 54 ? 32.537 23.531 18.812 1.00 16.70 ? 50 ILE A CD1 1 ATOM 431 N N . GLY A 1 55 ? 29.616 19.764 18.712 1.00 13.84 ? 51 GLY A N 1 ATOM 432 C CA . GLY A 1 55 ? 28.613 18.692 18.962 1.00 14.38 ? 51 GLY A CA 1 ATOM 433 C C . GLY A 1 55 ? 27.347 19.211 19.656 1.00 14.08 ? 51 GLY A C 1 ATOM 434 O O . GLY A 1 55 ? 26.292 18.580 19.514 1.00 14.16 ? 51 GLY A O 1 ATOM 435 N N . SER A 1 56 ? 27.430 20.327 20.366 1.00 13.77 ? 52 SER A N 1 ATOM 436 C CA . SER A 1 56 ? 26.270 20.717 21.176 1.00 12.99 ? 52 SER A CA 1 ATOM 437 C C . SER A 1 56 ? 26.344 22.199 21.459 1.00 13.36 ? 52 SER A C 1 ATOM 438 O O . SER A 1 56 ? 27.425 22.812 21.512 1.00 13.65 ? 52 SER A O 1 ATOM 439 C CB . SER A 1 56 ? 26.248 19.886 22.489 1.00 14.58 ? 52 SER A CB 1 ATOM 440 O OG . SER A 1 56 ? 25.136 20.276 23.313 1.00 13.82 ? 52 SER A OG 1 ATOM 441 N N . LEU A 1 57 ? 25.165 22.809 21.681 1.00 13.09 ? 53 LEU A N 1 ATOM 442 C CA . LEU A 1 57 ? 25.063 24.189 22.134 1.00 13.78 ? 53 LEU A CA 1 ATOM 443 C C . LEU A 1 57 ? 24.196 24.183 23.365 1.00 12.87 ? 53 LEU A C 1 ATOM 444 O O . LEU A 1 57 ? 23.411 23.237 23.552 1.00 13.67 ? 53 LEU A O 1 ATOM 445 C CB . LEU A 1 57 ? 24.325 25.066 21.110 1.00 14.95 ? 53 LEU A CB 1 ATOM 446 C CG . LEU A 1 57 ? 25.242 25.480 19.929 1.00 18.46 ? 53 LEU A CG 1 ATOM 447 C CD1 . LEU A 1 57 ? 25.138 24.421 18.845 1.00 22.75 ? 53 LEU A CD1 1 ATOM 448 C CD2 . LEU A 1 57 ? 24.845 26.824 19.388 1.00 23.91 ? 53 LEU A CD2 1 ATOM 449 N N . LEU A 1 58 ? 24.338 25.226 24.176 1.00 12.59 ? 54 LEU A N 1 ATOM 450 C CA . LEU A 1 58 ? 23.338 25.455 25.261 1.00 11.60 ? 54 LEU A CA 1 ATOM 451 C C . LEU A 1 58 ? 22.979 26.913 25.366 1.00 12.18 ? 54 LEU A C 1 ATOM 452 O O . LEU A 1 58 ? 23.708 27.798 24.940 1.00 12.62 ? 54 LEU A O 1 ATOM 453 C CB . LEU A 1 58 ? 23.823 24.942 26.659 1.00 11.89 ? 54 LEU A CB 1 ATOM 454 C CG . LEU A 1 58 ? 24.674 25.903 27.500 1.00 12.53 ? 54 LEU A CG 1 ATOM 455 C CD1 . LEU A 1 58 ? 24.587 25.443 28.978 1.00 13.53 ? 54 LEU A CD1 1 ATOM 456 C CD2 . LEU A 1 58 ? 26.122 25.786 26.995 1.00 13.33 ? 54 LEU A CD2 1 ATOM 457 N N . SER A 1 59 ? 21.812 27.162 25.973 1.00 11.66 ? 55 SER A N 1 ATOM 458 C CA . SER A 1 59 ? 21.526 28.443 26.636 1.00 12.36 ? 55 SER A CA 1 ATOM 459 C C . SER A 1 59 ? 21.701 28.189 28.115 1.00 13.13 ? 55 SER A C 1 ATOM 460 O O . SER A 1 59 ? 20.958 27.386 28.696 1.00 13.85 ? 55 SER A O 1 ATOM 461 C CB . SER A 1 59 ? 20.034 28.794 26.442 1.00 12.65 ? 55 SER A CB 1 ATOM 462 O OG . SER A 1 59 ? 19.808 29.421 25.149 1.00 12.98 ? 55 SER A OG 1 ATOM 463 N N . GLY A 1 60 ? 22.631 28.921 28.752 1.00 12.97 ? 56 GLY A N 1 ATOM 464 C CA . GLY A 1 60 ? 22.567 29.036 30.227 1.00 13.51 ? 56 GLY A CA 1 ATOM 465 C C . GLY A 1 60 ? 21.371 29.847 30.667 1.00 13.23 ? 56 GLY A C 1 ATOM 466 O O . GLY A 1 60 ? 20.594 30.373 29.853 1.00 13.79 ? 56 GLY A O 1 ATOM 467 N N . GLY A 1 61 ? 21.208 29.961 31.978 1.00 14.52 ? 57 GLY A N 1 ATOM 468 C CA . GLY A 1 61 ? 20.118 30.820 32.479 1.00 13.88 ? 57 GLY A CA 1 ATOM 469 C C . GLY A 1 61 ? 20.188 32.212 31.906 1.00 14.34 ? 57 GLY A C 1 ATOM 470 O O . GLY A 1 61 ? 21.263 32.842 31.902 1.00 16.12 ? 57 GLY A O 1 ATOM 471 N N . GLY A 1 62 ? 19.075 32.678 31.364 1.00 13.74 ? 58 GLY A N 1 ATOM 472 C CA . GLY A 1 62 ? 18.999 34.028 30.770 1.00 14.15 ? 58 GLY A CA 1 ATOM 473 C C . GLY A 1 62 ? 19.610 34.172 29.379 1.00 13.44 ? 58 GLY A C 1 ATOM 474 O O . GLY A 1 62 ? 19.614 35.291 28.870 1.00 15.22 ? 58 GLY A O 1 ATOM 475 N N . SER A 1 63 ? 20.077 33.087 28.752 1.00 13.21 ? 59 SER A N 1 ATOM 476 C CA . SER A 1 63 ? 20.740 33.210 27.429 1.00 13.23 ? 59 SER A CA 1 ATOM 477 C C . SER A 1 63 ? 19.640 32.993 26.379 1.00 14.35 ? 59 SER A C 1 ATOM 478 O O . SER A 1 63 ? 19.222 31.868 26.077 1.00 15.18 ? 59 SER A O 1 ATOM 479 C CB . SER A 1 63 ? 21.862 32.195 27.314 1.00 13.37 ? 59 SER A CB 1 ATOM 480 O OG . SER A 1 63 ? 22.460 32.361 26.015 1.00 15.31 ? 59 SER A OG 1 ATOM 481 N N . VAL A 1 64 ? 19.147 34.084 25.827 1.00 13.75 ? 60 VAL A N 1 ATOM 482 C CA . VAL A 1 64 ? 17.944 34.066 24.968 1.00 14.23 ? 60 VAL A CA 1 ATOM 483 C C . VAL A 1 64 ? 18.192 34.935 23.708 1.00 14.92 ? 60 VAL A C 1 ATOM 484 O O . VAL A 1 64 ? 19.017 35.845 23.734 1.00 16.51 ? 60 VAL A O 1 ATOM 485 C CB . VAL A 1 64 ? 16.715 34.612 25.736 1.00 13.74 ? 60 VAL A CB 1 ATOM 486 C CG1 . VAL A 1 64 ? 16.526 33.829 27.041 1.00 15.64 ? 60 VAL A CG1 1 ATOM 487 C CG2 . VAL A 1 64 ? 16.852 36.108 26.069 1.00 15.37 ? 60 VAL A CG2 1 ATOM 488 N N . PRO A 1 65 ? 17.512 34.634 22.603 1.00 15.27 ? 61 PRO A N 1 ATOM 489 C CA . PRO A 1 65 ? 17.837 35.373 21.361 1.00 15.67 ? 61 PRO A CA 1 ATOM 490 C C . PRO A 1 65 ? 17.429 36.838 21.468 1.00 17.57 ? 61 PRO A C 1 ATOM 491 O O . PRO A 1 65 ? 18.093 37.706 20.871 1.00 17.16 ? 61 PRO A O 1 ATOM 492 C CB . PRO A 1 65 ? 17.033 34.615 20.269 1.00 17.47 ? 61 PRO A CB 1 ATOM 493 C CG . PRO A 1 65 ? 15.974 33.799 21.059 1.00 15.63 ? 61 PRO A CG 1 ATOM 494 C CD . PRO A 1 65 ? 16.719 33.432 22.355 1.00 15.40 ? 61 PRO A CD 1 ATOM 495 N N . ARG A 1 66 ? 16.324 37.105 22.172 1.00 17.33 ? 62 ARG A N 1 ATOM 496 C CA . ARG A 1 66 ? 16.051 38.455 22.675 1.00 20.61 ? 62 ARG A CA 1 ATOM 497 C C . ARG A 1 66 ? 14.990 38.386 23.723 1.00 20.09 ? 62 ARG A C 1 ATOM 498 O O . ARG A 1 66 ? 14.340 37.369 23.863 1.00 16.93 ? 62 ARG A O 1 ATOM 499 C CB . ARG A 1 66 ? 15.648 39.413 21.626 1.00 23.62 ? 62 ARG A CB 1 ATOM 500 C CG . ARG A 1 66 ? 14.447 39.091 20.868 1.00 22.22 ? 62 ARG A CG 1 ATOM 501 C CD . ARG A 1 66 ? 14.356 39.905 19.540 1.00 31.63 ? 62 ARG A CD 1 ATOM 502 N NE . ARG A 1 66 ? 12.951 39.831 19.189 1.00 27.74 ? 62 ARG A NE 1 ATOM 503 C CZ . ARG A 1 66 ? 12.145 40.847 18.914 1.00 28.93 ? 62 ARG A CZ 1 ATOM 504 N NH1 . ARG A 1 66 ? 12.599 42.116 18.792 1.00 27.01 ? 62 ARG A NH1 1 ATOM 505 N NH2 . ARG A 1 66 ? 10.874 40.557 18.688 1.00 25.63 ? 62 ARG A NH2 1 ATOM 506 N N . LYS A 1 67 ? 14.861 39.503 24.447 1.00 21.58 ? 63 LYS A N 1 ATOM 507 C CA . LYS A 1 67 ? 13.844 39.557 25.457 1.00 22.09 ? 63 LYS A CA 1 ATOM 508 C C . LYS A 1 67 ? 12.479 39.424 24.850 1.00 19.23 ? 63 LYS A C 1 ATOM 509 O O . LYS A 1 67 ? 12.194 40.032 23.829 1.00 20.60 ? 63 LYS A O 1 ATOM 510 C CB . LYS A 1 67 ? 13.973 40.887 26.201 1.00 23.07 ? 63 LYS A CB 1 ATOM 511 C CG . LYS A 1 67 ? 13.995 40.569 27.673 1.00 32.45 ? 63 LYS A CG 1 ATOM 512 C CD . LYS A 1 67 ? 15.344 40.017 28.187 1.00 35.33 ? 63 LYS A CD 1 ATOM 513 C CE . LYS A 1 67 ? 15.125 39.130 29.443 1.00 40.86 ? 63 LYS A CE 1 ATOM 514 N NZ . LYS A 1 67 ? 14.926 39.714 30.838 1.00 39.74 ? 63 LYS A NZ 1 ATOM 515 N N . GLY A 1 68 ? 11.608 38.596 25.460 1.00 16.97 ? 64 GLY A N 1 ATOM 516 C CA . GLY A 1 68 ? 10.224 38.476 24.926 1.00 16.67 ? 64 GLY A CA 1 ATOM 517 C C . GLY A 1 68 ? 10.113 37.672 23.648 1.00 14.99 ? 64 GLY A C 1 ATOM 518 O O . GLY A 1 68 ? 9.073 37.685 22.974 1.00 16.96 ? 64 GLY A O 1 ATOM 519 N N . ALA A 1 69 ? 11.165 36.939 23.313 1.00 14.99 ? 65 ALA A N 1 ATOM 520 C CA . ALA A 1 69 ? 11.173 36.188 22.038 1.00 15.16 ? 65 ALA A CA 1 ATOM 521 C C . ALA A 1 69 ? 10.043 35.192 21.932 1.00 15.03 ? 65 ALA A C 1 ATOM 522 O O . ALA A 1 69 ? 9.698 34.478 22.904 1.00 15.95 ? 65 ALA A O 1 ATOM 523 C CB . ALA A 1 69 ? 12.549 35.483 21.846 1.00 14.89 ? 65 ALA A CB 1 ATOM 524 N N . THR A 1 70 ? 9.456 35.102 20.741 1.00 15.13 ? 66 THR A N 1 ATOM 525 C CA . THR A 1 70 ? 8.400 34.113 20.512 1.00 15.05 ? 66 THR A CA 1 ATOM 526 C C . THR A 1 70 ? 8.972 32.691 20.375 1.00 14.71 ? 66 THR A C 1 ATOM 527 O O . THR A 1 70 ? 10.204 32.498 20.166 1.00 14.21 ? 66 THR A O 1 ATOM 528 C CB . THR A 1 70 ? 7.598 34.406 19.244 1.00 16.33 ? 66 THR A CB 1 ATOM 529 O OG1 . THR A 1 70 ? 8.474 34.255 18.101 1.00 17.34 ? 66 THR A OG1 1 ATOM 530 C CG2 . THR A 1 70 ? 7.083 35.858 19.290 1.00 19.48 ? 66 THR A CG2 1 ATOM 531 N N . ALA A 1 71 ? 8.109 31.696 20.495 1.00 15.14 ? 67 ALA A N 1 ATOM 532 C CA . ALA A 1 71 ? 8.521 30.298 20.225 1.00 13.66 ? 67 ALA A CA 1 ATOM 533 C C . ALA A 1 71 ? 9.160 30.169 18.833 1.00 15.11 ? 67 ALA A C 1 ATOM 534 O O . ALA A 1 71 ? 10.183 29.475 18.674 1.00 15.24 ? 67 ALA A O 1 ATOM 535 C CB . ALA A 1 71 ? 7.345 29.338 20.369 1.00 16.17 ? 67 ALA A CB 1 ATOM 536 N N . LYS A 1 72 ? 8.547 30.842 17.833 1.00 15.22 ? 68 LYS A N 1 ATOM 537 C CA . LYS A 1 72 ? 9.118 30.845 16.470 1.00 16.38 ? 68 LYS A CA 1 ATOM 538 C C . LYS A 1 72 ? 10.521 31.451 16.448 1.00 15.70 ? 68 LYS A C 1 ATOM 539 O O . LYS A 1 72 ? 11.421 30.917 15.744 1.00 15.40 ? 68 LYS A O 1 ATOM 540 C CB . LYS A 1 72 ? 8.183 31.587 15.514 1.00 17.87 ? 68 LYS A CB 1 ATOM 541 C CG . LYS A 1 72 ? 8.734 31.713 14.090 1.00 23.60 ? 68 LYS A CG 1 ATOM 542 C CD . LYS A 1 72 ? 8.693 30.321 13.400 1.00 37.10 ? 68 LYS A CD 1 ATOM 543 C CE . LYS A 1 72 ? 8.206 30.440 11.935 1.00 40.71 ? 68 LYS A CE 1 ATOM 544 N NZ . LYS A 1 72 ? 8.444 29.230 11.081 1.00 41.10 ? 68 LYS A NZ 1 ATOM 545 N N . GLU A 1 73 ? 10.756 32.565 17.177 1.00 14.90 ? 69 GLU A N 1 ATOM 546 C CA . GLU A 1 73 ? 12.139 33.102 17.227 1.00 14.36 ? 69 GLU A CA 1 ATOM 547 C C . GLU A 1 73 ? 13.144 32.087 17.770 1.00 14.32 ? 69 GLU A C 1 ATOM 548 O O . GLU A 1 73 ? 14.274 31.997 17.248 1.00 14.77 ? 69 GLU A O 1 ATOM 549 C CB . GLU A 1 73 ? 12.233 34.353 18.079 1.00 15.50 ? 69 GLU A CB 1 ATOM 550 C CG . GLU A 1 73 ? 11.583 35.544 17.358 1.00 17.21 ? 69 GLU A CG 1 ATOM 551 C CD . GLU A 1 73 ? 11.660 36.773 18.241 1.00 19.99 ? 69 GLU A CD 1 ATOM 552 O OE1 . GLU A 1 73 ? 10.600 37.174 18.756 1.00 20.93 ? 69 GLU A OE1 1 ATOM 553 O OE2 . GLU A 1 73 ? 12.778 37.275 18.514 1.00 22.19 ? 69 GLU A OE2 1 ATOM 554 N N . TRP A 1 74 ? 12.779 31.355 18.839 1.00 13.60 ? 70 TRP A N 1 ATOM 555 C CA . TRP A 1 74 ? 13.660 30.301 19.357 1.00 12.89 ? 70 TRP A CA 1 ATOM 556 C C . TRP A 1 74 ? 13.880 29.230 18.294 1.00 12.89 ? 70 TRP A C 1 ATOM 557 O O . TRP A 1 74 ? 15.033 28.850 18.043 1.00 13.52 ? 70 TRP A O 1 ATOM 558 C CB . TRP A 1 74 ? 13.026 29.686 20.622 1.00 12.19 ? 70 TRP A CB 1 ATOM 559 C CG . TRP A 1 74 ? 13.212 30.500 21.852 1.00 13.22 ? 70 TRP A CG 1 ATOM 560 C CD1 . TRP A 1 74 ? 12.360 31.440 22.355 1.00 12.87 ? 70 TRP A CD1 1 ATOM 561 C CD2 . TRP A 1 74 ? 14.329 30.434 22.766 1.00 12.10 ? 70 TRP A CD2 1 ATOM 562 N NE1 . TRP A 1 74 ? 12.879 31.983 23.536 1.00 12.95 ? 70 TRP A NE1 1 ATOM 563 C CE2 . TRP A 1 74 ? 14.086 31.352 23.810 1.00 11.74 ? 70 TRP A CE2 1 ATOM 564 C CE3 . TRP A 1 74 ? 15.489 29.641 22.814 1.00 14.49 ? 70 TRP A CE3 1 ATOM 565 C CZ2 . TRP A 1 74 ? 14.964 31.502 24.891 1.00 12.42 ? 70 TRP A CZ2 1 ATOM 566 C CZ3 . TRP A 1 74 ? 16.365 29.808 23.887 1.00 12.84 ? 70 TRP A CZ3 1 ATOM 567 C CH2 . TRP A 1 74 ? 16.100 30.743 24.906 1.00 13.30 ? 70 TRP A CH2 1 ATOM 568 N N . GLN A 1 75 ? 12.812 28.793 17.599 1.00 13.31 ? 71 GLN A N 1 ATOM 569 C CA . GLN A 1 75 ? 12.985 27.718 16.602 1.00 13.61 ? 71 GLN A CA 1 ATOM 570 C C . GLN A 1 75 ? 13.920 28.195 15.501 1.00 13.78 ? 71 GLN A C 1 ATOM 571 O O . GLN A 1 75 ? 14.755 27.418 15.055 1.00 15.04 ? 71 GLN A O 1 ATOM 572 C CB . GLN A 1 75 ? 11.626 27.366 15.989 1.00 12.68 ? 71 GLN A CB 1 ATOM 573 C CG . GLN A 1 75 ? 10.745 26.588 16.946 1.00 13.99 ? 71 GLN A CG 1 ATOM 574 C CD . GLN A 1 75 ? 9.621 25.824 16.236 1.00 18.33 ? 71 GLN A CD 1 ATOM 575 O OE1 . GLN A 1 75 ? 8.752 25.198 16.889 1.00 21.37 ? 71 GLN A OE1 1 ATOM 576 N NE2 . GLN A 1 75 ? 9.632 25.845 14.936 1.00 15.97 ? 71 GLN A NE2 1 ATOM 577 N N . ASP A 1 76 ? 13.746 29.445 15.077 1.00 14.41 ? 72 ASP A N 1 ATOM 578 C CA . ASP A 1 76 ? 14.613 29.981 13.973 1.00 16.42 ? 72 ASP A CA 1 ATOM 579 C C . ASP A 1 76 ? 16.059 30.082 14.417 1.00 15.73 ? 72 ASP A C 1 ATOM 580 O O . ASP A 1 76 ? 16.970 29.774 13.639 1.00 16.77 ? 72 ASP A O 1 ATOM 581 C CB . ASP A 1 76 ? 14.080 31.317 13.467 1.00 17.10 ? 72 ASP A CB 1 ATOM 582 C CG . ASP A 1 76 ? 12.733 31.168 12.722 1.00 17.47 ? 72 ASP A CG 1 ATOM 583 O OD1 . ASP A 1 76 ? 12.347 30.041 12.280 1.00 20.26 ? 72 ASP A OD1 1 ATOM 584 O OD2 . ASP A 1 76 ? 12.089 32.226 12.572 1.00 21.13 ? 72 ASP A OD2 1 ATOM 585 N N . MET A 1 77 ? 16.285 30.470 15.675 1.00 14.75 ? 73 MET A N 1 ATOM 586 C CA . MET A 1 77 ? 17.643 30.488 16.195 1.00 14.31 ? 73 MET A CA 1 ATOM 587 C C . MET A 1 77 ? 18.246 29.071 16.197 1.00 13.85 ? 73 MET A C 1 ATOM 588 O O . MET A 1 77 ? 19.399 28.864 15.740 1.00 14.72 ? 73 MET A O 1 ATOM 589 C CB . MET A 1 77 ? 17.634 31.078 17.607 1.00 14.61 ? 73 MET A CB 1 ATOM 590 C CG . MET A 1 77 ? 19.040 31.102 18.188 1.00 14.72 ? 73 MET A CG 1 ATOM 591 S SD . MET A 1 77 ? 19.086 31.371 19.978 1.00 16.71 ? 73 MET A SD 1 ATOM 592 C CE . MET A 1 77 ? 18.433 29.809 20.600 1.00 16.04 ? 73 MET A CE 1 ATOM 593 N N . VAL A 1 78 ? 17.543 28.109 16.785 1.00 13.74 ? 74 VAL A N 1 ATOM 594 C CA . VAL A 1 78 ? 18.087 26.774 16.894 1.00 14.24 ? 74 VAL A CA 1 ATOM 595 C C . VAL A 1 78 ? 18.322 26.162 15.488 1.00 14.74 ? 74 VAL A C 1 ATOM 596 O O . VAL A 1 78 ? 19.371 25.554 15.249 1.00 14.85 ? 74 VAL A O 1 ATOM 597 C CB . VAL A 1 78 ? 17.200 25.869 17.766 1.00 15.94 ? 74 VAL A CB 1 ATOM 598 C CG1 . VAL A 1 78 ? 17.797 24.442 17.813 1.00 16.07 ? 74 VAL A CG1 1 ATOM 599 C CG2 . VAL A 1 78 ? 17.093 26.472 19.196 1.00 16.46 ? 74 VAL A CG2 1 ATOM 600 N N . ASP A 1 79 ? 17.351 26.318 14.586 1.00 14.79 ? 75 ASP A N 1 ATOM 601 C CA . ASP A 1 79 ? 17.536 25.868 13.218 1.00 15.52 ? 75 ASP A CA 1 ATOM 602 C C . ASP A 1 79 ? 18.682 26.530 12.506 1.00 15.90 ? 75 ASP A C 1 ATOM 603 O O . ASP A 1 79 ? 19.331 25.835 11.714 1.00 16.94 ? 75 ASP A O 1 ATOM 604 C CB . ASP A 1 79 ? 16.249 26.077 12.412 1.00 16.23 ? 75 ASP A CB 1 ATOM 605 C CG . ASP A 1 79 ? 15.135 25.109 12.766 1.00 17.75 ? 75 ASP A CG 1 ATOM 606 O OD1 . ASP A 1 79 ? 15.330 24.061 13.393 1.00 19.13 ? 75 ASP A OD1 1 ATOM 607 O OD2 . ASP A 1 79 ? 13.957 25.426 12.322 1.00 20.39 ? 75 ASP A OD2 1 ATOM 608 N N . GLY A 1 80 ? 18.924 27.812 12.751 1.00 15.99 ? 76 GLY A N 1 ATOM 609 C CA . GLY A 1 80 ? 20.121 28.516 12.140 1.00 16.89 ? 76 GLY A CA 1 ATOM 610 C C . GLY A 1 80 ? 21.394 27.805 12.555 1.00 17.78 ? 76 GLY A C 1 ATOM 611 O O . GLY A 1 80 ? 22.280 27.499 11.722 1.00 18.73 ? 76 GLY A O 1 ATOM 612 N N . PHE A 1 81 ? 21.515 27.495 13.841 1.00 16.47 ? 77 PHE A N 1 ATOM 613 C CA . PHE A 1 81 ? 22.694 26.769 14.324 1.00 15.85 ? 77 PHE A CA 1 ATOM 614 C C . PHE A 1 81 ? 22.755 25.360 13.738 1.00 16.58 ? 77 PHE A C 1 ATOM 615 O O . PHE A 1 81 ? 23.853 24.870 13.339 1.00 16.66 ? 77 PHE A O 1 ATOM 616 C CB . PHE A 1 81 ? 22.718 26.689 15.863 1.00 14.57 ? 77 PHE A CB 1 ATOM 617 C CG . PHE A 1 81 ? 22.828 28.017 16.553 1.00 15.45 ? 77 PHE A CG 1 ATOM 618 C CD1 . PHE A 1 81 ? 23.765 29.018 16.114 1.00 16.11 ? 77 PHE A CD1 1 ATOM 619 C CD2 . PHE A 1 81 ? 22.034 28.263 17.678 1.00 15.46 ? 77 PHE A CD2 1 ATOM 620 C CE1 . PHE A 1 81 ? 23.857 30.245 16.839 1.00 18.09 ? 77 PHE A CE1 1 ATOM 621 C CE2 . PHE A 1 81 ? 22.159 29.445 18.412 1.00 16.29 ? 77 PHE A CE2 1 ATOM 622 C CZ . PHE A 1 81 ? 23.036 30.439 17.973 1.00 16.73 ? 77 PHE A CZ 1 ATOM 623 N N . GLN A 1 82 ? 21.612 24.686 13.666 1.00 15.52 ? 78 GLN A N 1 ATOM 624 C CA . GLN A 1 82 ? 21.580 23.329 13.140 1.00 14.27 ? 78 GLN A CA 1 ATOM 625 C C . GLN A 1 82 ? 21.993 23.305 11.663 1.00 16.45 ? 78 GLN A C 1 ATOM 626 O O . GLN A 1 82 ? 22.714 22.374 11.254 1.00 16.76 ? 78 GLN A O 1 ATOM 627 C CB . GLN A 1 82 ? 20.162 22.720 13.314 1.00 16.09 ? 78 GLN A CB 1 ATOM 628 C CG . GLN A 1 82 ? 20.096 21.236 13.028 1.00 15.61 ? 78 GLN A CG 1 ATOM 629 C CD . GLN A 1 82 ? 20.880 20.443 14.073 1.00 16.31 ? 78 GLN A CD 1 ATOM 630 O OE1 . GLN A 1 82 ? 22.125 20.446 14.052 1.00 15.83 ? 78 GLN A OE1 1 ATOM 631 N NE2 . GLN A 1 82 ? 20.188 19.787 15.019 1.00 15.42 ? 78 GLN A NE2 1 ATOM 632 N N . LYS A 1 83 ? 21.547 24.291 10.888 1.00 17.25 ? 79 LYS A N 1 ATOM 633 C CA . LYS A 1 83 ? 21.869 24.317 9.449 1.00 19.18 ? 79 LYS A CA 1 ATOM 634 C C . LYS A 1 83 ? 23.397 24.339 9.288 1.00 17.87 ? 79 LYS A C 1 ATOM 635 O O . LYS A 1 83 ? 23.912 23.639 8.403 1.00 19.32 ? 79 LYS A O 1 ATOM 636 C CB . LYS A 1 83 ? 21.251 25.533 8.778 1.00 20.17 ? 79 LYS A CB 1 ATOM 637 C CG . LYS A 1 83 ? 21.515 25.583 7.227 1.00 26.87 ? 79 LYS A CG 1 ATOM 638 C CD . LYS A 1 83 ? 20.543 24.627 6.497 1.00 37.28 ? 79 LYS A CD 1 ATOM 639 C CE . LYS A 1 83 ? 20.815 24.480 4.975 1.00 42.53 ? 79 LYS A CE 1 ATOM 640 N NZ . LYS A 1 83 ? 20.304 23.138 4.508 1.00 45.64 ? 79 LYS A NZ 1 ATOM 641 N N . ALA A 1 84 ? 24.103 25.113 10.136 1.00 17.58 ? 80 ALA A N 1 ATOM 642 C CA . ALA A 1 84 ? 25.572 25.141 10.074 1.00 17.70 ? 80 ALA A CA 1 ATOM 643 C C . ALA A 1 84 ? 26.162 23.792 10.416 1.00 18.82 ? 80 ALA A C 1 ATOM 644 O O . ALA A 1 84 ? 27.076 23.291 9.703 1.00 19.36 ? 80 ALA A O 1 ATOM 645 C CB . ALA A 1 84 ? 26.119 26.241 11.011 1.00 17.87 ? 80 ALA A CB 1 ATOM 646 N N . CYS A 1 85 ? 25.654 23.116 11.473 1.00 17.27 ? 81 CYS A N 1 ATOM 647 C CA . CYS A 1 85 ? 26.206 21.822 11.845 1.00 17.09 ? 81 CYS A CA 1 ATOM 648 C C . CYS A 1 85 ? 25.950 20.755 10.790 1.00 18.19 ? 81 CYS A C 1 ATOM 649 O O . CYS A 1 85 ? 26.806 19.899 10.507 1.00 19.24 ? 81 CYS A O 1 ATOM 650 C CB . CYS A 1 85 ? 25.645 21.360 13.243 1.00 17.16 ? 81 CYS A CB 1 ATOM 651 S SG . CYS A 1 85 ? 26.127 22.441 14.528 1.00 18.42 ? 81 CYS A SG 1 ATOM 652 N N . MET A 1 86 ? 24.780 20.819 10.132 1.00 17.25 ? 82 MET A N 1 ATOM 653 C CA . MET A 1 86 ? 24.418 19.823 9.132 1.00 18.36 ? 82 MET A CA 1 ATOM 654 C C . MET A 1 86 ? 25.230 20.022 7.836 1.00 18.14 ? 82 MET A C 1 ATOM 655 O O . MET A 1 86 ? 25.241 19.119 6.977 1.00 20.53 ? 82 MET A O 1 ATOM 656 C CB . MET A 1 86 ? 22.927 19.937 8.835 1.00 19.05 ? 82 MET A CB 1 ATOM 657 C CG . MET A 1 86 ? 22.050 19.402 9.998 1.00 20.06 ? 82 MET A CG 1 ATOM 658 S SD . MET A 1 86 ? 22.446 17.745 10.558 1.00 25.06 ? 82 MET A SD 1 ATOM 659 C CE . MET A 1 86 ? 21.907 16.640 9.221 1.00 26.76 ? 82 MET A CE 1 ATOM 660 N N . SER A 1 87 ? 25.901 21.168 7.740 1.00 17.90 ? 83 SER A N 1 ATOM 661 C CA . SER A 1 87 ? 26.717 21.491 6.543 1.00 19.63 ? 83 SER A CA 1 ATOM 662 C C . SER A 1 87 ? 28.149 21.033 6.660 1.00 20.23 ? 83 SER A C 1 ATOM 663 O O . SER A 1 87 ? 28.940 21.213 5.676 1.00 20.89 ? 83 SER A O 1 ATOM 664 C CB . SER A 1 87 ? 26.695 22.988 6.232 1.00 19.13 ? 83 SER A CB 1 ATOM 665 O OG . SER A 1 87 ? 27.523 23.713 7.105 1.00 20.72 ? 83 SER A OG 1 ATOM 666 N N . THR A 1 88 ? 28.511 20.443 7.791 1.00 17.99 ? 84 THR A N 1 ATOM 667 C CA . THR A 1 88 ? 29.841 19.801 7.895 1.00 17.59 ? 84 THR A CA 1 ATOM 668 C C . THR A 1 88 ? 29.936 18.573 7.001 1.00 18.47 ? 84 THR A C 1 ATOM 669 O O . THR A 1 88 ? 28.947 18.058 6.495 1.00 18.21 ? 84 THR A O 1 ATOM 670 C CB . THR A 1 88 ? 30.171 19.319 9.321 1.00 17.96 ? 84 THR A CB 1 ATOM 671 O OG1 . THR A 1 88 ? 29.180 18.373 9.736 1.00 16.78 ? 84 THR A OG1 1 ATOM 672 C CG2 . THR A 1 88 ? 30.186 20.506 10.338 1.00 17.18 ? 84 THR A CG2 1 ATOM 673 N N . ARG A 1 89 ? 31.173 18.121 6.798 1.00 17.90 ? 85 ARG A N 1 ATOM 674 C CA . ARG A 1 89 ? 31.432 16.951 5.945 1.00 18.43 ? 85 ARG A CA 1 ATOM 675 C C . ARG A 1 89 ? 30.515 15.764 6.303 1.00 18.18 ? 85 ARG A C 1 ATOM 676 O O . ARG A 1 89 ? 29.915 15.140 5.403 1.00 17.87 ? 85 ARG A O 1 ATOM 677 C CB . ARG A 1 89 ? 32.896 16.573 6.136 1.00 18.64 ? 85 ARG A CB 1 ATOM 678 C CG . ARG A 1 89 ? 33.289 15.396 5.257 1.00 18.11 ? 85 ARG A CG 1 ATOM 679 C CD . ARG A 1 89 ? 34.759 15.107 5.569 1.00 20.75 ? 85 ARG A CD 1 ATOM 680 N NE . ARG A 1 89 ? 34.914 14.309 6.791 1.00 17.14 ? 85 ARG A NE 1 ATOM 681 C CZ . ARG A 1 89 ? 35.129 13.026 6.814 1.00 18.54 ? 85 ARG A CZ 1 ATOM 682 N NH1 . ARG A 1 89 ? 35.152 12.339 5.657 1.00 22.03 ? 85 ARG A NH1 1 ATOM 683 N NH2 . ARG A 1 89 ? 35.333 12.406 7.969 1.00 21.44 ? 85 ARG A NH2 1 ATOM 684 N N . LEU A 1 90 ? 30.347 15.469 7.598 1.00 16.83 ? 86 LEU A N 1 ATOM 685 C CA . LEU A 1 90 ? 29.616 14.271 8.011 1.00 15.55 ? 86 LEU A CA 1 ATOM 686 C C . LEU A 1 90 ? 28.160 14.610 8.363 1.00 16.79 ? 86 LEU A C 1 ATOM 687 O O . LEU A 1 90 ? 27.358 13.707 8.483 1.00 17.69 ? 86 LEU A O 1 ATOM 688 C CB . LEU A 1 90 ? 30.268 13.601 9.241 1.00 17.01 ? 86 LEU A CB 1 ATOM 689 C CG . LEU A 1 90 ? 31.684 13.019 8.999 1.00 16.97 ? 86 LEU A CG 1 ATOM 690 C CD1 . LEU A 1 90 ? 32.273 12.486 10.303 1.00 18.61 ? 86 LEU A CD1 1 ATOM 691 C CD2 . LEU A 1 90 ? 31.598 11.859 7.974 1.00 20.71 ? 86 LEU A CD2 1 ATOM 692 N N . GLY A 1 91 ? 27.861 15.899 8.499 1.00 16.20 ? 87 GLY A N 1 ATOM 693 C CA . GLY A 1 91 ? 26.456 16.347 8.759 1.00 16.89 ? 87 GLY A CA 1 ATOM 694 C C . GLY A 1 91 ? 25.896 15.795 10.068 1.00 16.40 ? 87 GLY A C 1 ATOM 695 O O . GLY A 1 91 ? 24.777 15.240 10.125 1.00 18.29 ? 87 GLY A O 1 ATOM 696 N N . ILE A 1 92 ? 26.681 15.880 11.137 1.00 15.43 ? 88 ILE A N 1 ATOM 697 C CA . ILE A 1 92 ? 26.220 15.397 12.438 1.00 14.84 ? 88 ILE A CA 1 ATOM 698 C C . ILE A 1 92 ? 25.436 16.535 13.096 1.00 15.04 ? 88 ILE A C 1 ATOM 699 O O . ILE A 1 92 ? 25.978 17.590 13.362 1.00 14.44 ? 88 ILE A O 1 ATOM 700 C CB . ILE A 1 92 ? 27.423 15.016 13.386 1.00 14.84 ? 88 ILE A CB 1 ATOM 701 C CG1 . ILE A 1 92 ? 28.294 13.932 12.691 1.00 15.47 ? 88 ILE A CG1 1 ATOM 702 C CG2 . ILE A 1 92 ? 26.832 14.480 14.737 1.00 15.48 ? 88 ILE A CG2 1 ATOM 703 C CD1 . ILE A 1 92 ? 29.641 13.664 13.455 1.00 16.71 ? 88 ILE A CD1 1 ATOM 704 N N . PRO A 1 93 ? 24.128 16.315 13.389 1.00 15.22 ? 89 PRO A N 1 ATOM 705 C CA . PRO A 1 93 ? 23.358 17.389 14.000 1.00 14.72 ? 89 PRO A CA 1 ATOM 706 C C . PRO A 1 93 ? 23.819 17.670 15.424 1.00 13.53 ? 89 PRO A C 1 ATOM 707 O O . PRO A 1 93 ? 24.200 16.744 16.147 1.00 14.61 ? 89 PRO A O 1 ATOM 708 C CB . PRO A 1 93 ? 21.932 16.784 13.994 1.00 13.71 ? 89 PRO A CB 1 ATOM 709 C CG . PRO A 1 93 ? 22.144 15.296 14.193 1.00 14.60 ? 89 PRO A CG 1 ATOM 710 C CD . PRO A 1 93 ? 23.361 15.058 13.251 1.00 16.05 ? 89 PRO A CD 1 ATOM 711 N N . MET A 1 94 ? 23.778 18.954 15.792 1.00 13.07 ? 90 MET A N 1 ATOM 712 C CA . MET A 1 94 ? 24.034 19.289 17.179 1.00 12.97 ? 90 MET A CA 1 ATOM 713 C C . MET A 1 94 ? 22.766 19.011 18.015 1.00 13.36 ? 90 MET A C 1 ATOM 714 O O . MET A 1 94 ? 21.637 18.963 17.489 1.00 14.38 ? 90 MET A O 1 ATOM 715 C CB . MET A 1 94 ? 24.478 20.749 17.317 1.00 13.63 ? 90 MET A CB 1 ATOM 716 C CG . MET A 1 94 ? 23.454 21.826 16.891 1.00 14.58 ? 90 MET A CG 1 ATOM 717 S SD . MET A 1 94 ? 22.259 22.172 18.251 1.00 15.34 ? 90 MET A SD 1 ATOM 718 C CE . MET A 1 94 ? 20.834 22.686 17.287 1.00 19.89 ? 90 MET A CE 1 ATOM 719 N N . ILE A 1 95 ? 23.013 18.819 19.312 1.00 13.27 ? 91 ILE A N 1 ATOM 720 C CA . ILE A 1 95 ? 21.908 18.747 20.297 1.00 12.38 ? 91 ILE A CA 1 ATOM 721 C C . ILE A 1 95 ? 21.993 20.076 21.088 1.00 13.40 ? 91 ILE A C 1 ATOM 722 O O . ILE A 1 95 ? 23.078 20.502 21.526 1.00 13.73 ? 91 ILE A O 1 ATOM 723 C CB . ILE A 1 95 ? 22.049 17.473 21.171 1.00 13.04 ? 91 ILE A CB 1 ATOM 724 C CG1 . ILE A 1 95 ? 20.823 17.318 22.096 1.00 15.58 ? 91 ILE A CG1 1 ATOM 725 C CG2 . ILE A 1 95 ? 23.314 17.473 22.036 1.00 15.35 ? 91 ILE A CG2 1 ATOM 726 C CD1 . ILE A 1 95 ? 20.870 16.027 22.899 1.00 14.32 ? 91 ILE A CD1 1 ATOM 727 N N . TYR A 1 96 ? 20.853 20.718 21.302 1.00 12.19 ? 92 TYR A N 1 ATOM 728 C CA . TYR A 1 96 ? 20.804 22.021 22.015 1.00 12.09 ? 92 TYR A CA 1 ATOM 729 C C . TYR A 1 96 ? 20.180 21.773 23.381 1.00 13.35 ? 92 TYR A C 1 ATOM 730 O O . TYR A 1 96 ? 19.052 21.217 23.468 1.00 12.96 ? 92 TYR A O 1 ATOM 731 C CB . TYR A 1 96 ? 19.921 22.994 21.194 1.00 12.33 ? 92 TYR A CB 1 ATOM 732 C CG . TYR A 1 96 ? 20.071 24.444 21.629 1.00 12.12 ? 92 TYR A CG 1 ATOM 733 C CD1 . TYR A 1 96 ? 19.573 24.920 22.868 1.00 11.66 ? 92 TYR A CD1 1 ATOM 734 C CD2 . TYR A 1 96 ? 20.739 25.364 20.784 1.00 12.15 ? 92 TYR A CD2 1 ATOM 735 C CE1 . TYR A 1 96 ? 19.798 26.256 23.269 1.00 11.48 ? 92 TYR A CE1 1 ATOM 736 C CE2 . TYR A 1 96 ? 20.914 26.668 21.155 1.00 14.12 ? 92 TYR A CE2 1 ATOM 737 C CZ . TYR A 1 96 ? 20.418 27.119 22.369 1.00 12.46 ? 92 TYR A CZ 1 ATOM 738 O OH . TYR A 1 96 ? 20.665 28.438 22.702 1.00 12.99 ? 92 TYR A OH 1 ATOM 739 N N . GLY A 1 97 ? 20.889 22.182 24.435 1.00 12.33 ? 93 GLY A N 1 ATOM 740 C CA . GLY A 1 97 ? 20.410 21.963 25.806 1.00 11.84 ? 93 GLY A CA 1 ATOM 741 C C . GLY A 1 97 ? 20.005 23.257 26.494 1.00 11.53 ? 93 GLY A C 1 ATOM 742 O O . GLY A 1 97 ? 20.456 24.353 26.146 1.00 12.81 ? 93 GLY A O 1 ATOM 743 N N . ILE A 1 98 ? 19.111 23.134 27.482 1.00 11.02 ? 94 ILE A N 1 ATOM 744 C CA . ILE A 1 98 ? 18.692 24.294 28.266 1.00 11.07 ? 94 ILE A CA 1 ATOM 745 C C . ILE A 1 98 ? 18.187 23.834 29.640 1.00 11.07 ? 94 ILE A C 1 ATOM 746 O O . ILE A 1 98 ? 17.722 22.675 29.786 1.00 11.65 ? 94 ILE A O 1 ATOM 747 C CB . ILE A 1 98 ? 17.550 25.058 27.495 1.00 12.85 ? 94 ILE A CB 1 ATOM 748 C CG1 . ILE A 1 98 ? 17.431 26.491 28.039 1.00 10.84 ? 94 ILE A CG1 1 ATOM 749 C CG2 . ILE A 1 98 ? 16.242 24.233 27.509 1.00 12.70 ? 94 ILE A CG2 1 ATOM 750 C CD1 . ILE A 1 98 ? 16.590 27.391 27.115 1.00 12.35 ? 94 ILE A CD1 1 ATOM 751 N N . ASP A 1 99 ? 18.246 24.741 30.612 1.00 12.20 ? 95 ASP A N 1 ATOM 752 C CA . ASP A 1 99 ? 17.652 24.409 31.943 1.00 12.13 ? 95 ASP A CA 1 ATOM 753 C C . ASP A 1 99 ? 16.138 24.626 31.898 1.00 11.69 ? 95 ASP A C 1 ATOM 754 O O . ASP A 1 99 ? 15.666 25.734 32.156 1.00 13.53 ? 95 ASP A O 1 ATOM 755 C CB . ASP A 1 99 ? 18.274 25.246 33.062 1.00 12.93 ? 95 ASP A CB 1 ATOM 756 C CG . ASP A 1 99 ? 19.758 24.963 33.185 1.00 13.41 ? 95 ASP A CG 1 ATOM 757 O OD1 . ASP A 1 99 ? 20.074 23.887 33.723 1.00 14.39 ? 95 ASP A OD1 1 ATOM 758 O OD2 . ASP A 1 99 ? 20.537 25.752 32.627 1.00 13.62 ? 95 ASP A OD2 1 ATOM 759 N N . ALA A 1 100 ? 15.420 23.594 31.474 1.00 12.06 ? 96 ALA A N 1 ATOM 760 C CA . ALA A 1 100 ? 13.937 23.608 31.629 1.00 12.24 ? 96 ALA A CA 1 ATOM 761 C C . ALA A 1 100 ? 13.696 22.801 32.881 1.00 12.44 ? 96 ALA A C 1 ATOM 762 O O . ALA A 1 100 ? 13.561 21.560 32.806 1.00 13.15 ? 96 ALA A O 1 ATOM 763 C CB . ALA A 1 100 ? 13.316 22.921 30.390 1.00 12.81 ? 96 ALA A CB 1 ATOM 764 N N . VAL A 1 101 ? 13.764 23.477 34.015 1.00 12.94 ? 97 VAL A N 1 ATOM 765 C CA . VAL A 1 101 ? 13.776 22.817 35.355 1.00 11.64 ? 97 VAL A CA 1 ATOM 766 C C . VAL A 1 101 ? 12.471 23.041 36.096 1.00 13.22 ? 97 VAL A C 1 ATOM 767 O O . VAL A 1 101 ? 12.247 22.368 37.089 1.00 14.66 ? 97 VAL A O 1 ATOM 768 C CB . VAL A 1 101 ? 14.975 23.210 36.233 1.00 12.80 ? 97 VAL A CB 1 ATOM 769 C CG1 . VAL A 1 101 ? 16.277 22.699 35.541 1.00 14.56 ? 97 VAL A CG1 1 ATOM 770 C CG2 . VAL A 1 101 ? 15.053 24.750 36.457 1.00 13.03 ? 97 VAL A CG2 1 ATOM 771 N N . HIS A 1 102 ? 11.611 23.946 35.619 1.00 12.98 ? 98 HIS A N 1 ATOM 772 C CA . HIS A 1 102 ? 10.206 24.019 36.173 1.00 11.89 ? 98 HIS A CA 1 ATOM 773 C C . HIS A 1 102 ? 9.338 24.589 35.078 1.00 11.36 ? 98 HIS A C 1 ATOM 774 O O . HIS A 1 102 ? 8.788 25.708 35.167 1.00 13.47 ? 98 HIS A O 1 ATOM 775 C CB . HIS A 1 102 ? 10.113 24.752 37.544 1.00 12.39 ? 98 HIS A CB 1 ATOM 776 C CG . HIS A 1 102 ? 10.516 26.201 37.563 1.00 12.67 ? 98 HIS A CG 1 ATOM 777 N ND1 . HIS A 1 102 ? 9.879 27.132 38.359 1.00 12.65 ? 98 HIS A ND1 1 ATOM 778 C CD2 . HIS A 1 102 ? 11.496 26.868 36.904 1.00 12.13 ? 98 HIS A CD2 1 ATOM 779 C CE1 . HIS A 1 102 ? 10.450 28.325 38.186 1.00 13.20 ? 98 HIS A CE1 1 ATOM 780 N NE2 . HIS A 1 102 ? 11.433 28.176 37.311 1.00 12.40 ? 98 HIS A NE2 1 ATOM 781 N N . GLY A 1 103 ? 9.253 23.795 34.002 1.00 11.52 ? 99 GLY A N 1 ATOM 782 C CA . GLY A 1 103 ? 8.739 24.324 32.756 1.00 11.16 ? 99 GLY A CA 1 ATOM 783 C C . GLY A 1 103 ? 9.949 24.779 31.918 1.00 12.02 ? 99 GLY A C 1 ATOM 784 O O . GLY A 1 103 ? 11.103 24.694 32.342 1.00 13.26 ? 99 GLY A O 1 ATOM 785 N N . GLN A 1 104 ? 9.639 25.317 30.744 1.00 12.62 ? 100 GLN A N 1 ATOM 786 C CA . GLN A 1 104 ? 10.687 25.846 29.811 1.00 11.38 ? 100 GLN A CA 1 ATOM 787 C C . GLN A 1 104 ? 10.988 27.282 30.257 1.00 12.15 ? 100 GLN A C 1 ATOM 788 O O . GLN A 1 104 ? 10.623 28.273 29.609 1.00 12.55 ? 100 GLN A O 1 ATOM 789 C CB . GLN A 1 104 ? 10.113 25.721 28.395 1.00 12.12 ? 100 GLN A CB 1 ATOM 790 C CG . GLN A 1 104 ? 10.923 26.376 27.237 1.00 12.32 ? 100 GLN A CG 1 ATOM 791 C CD . GLN A 1 104 ? 12.380 25.948 27.126 1.00 13.28 ? 100 GLN A CD 1 ATOM 792 O OE1 . GLN A 1 104 ? 12.935 25.875 25.974 1.00 15.64 ? 100 GLN A OE1 1 ATOM 793 N NE2 . GLN A 1 104 ? 13.028 25.746 28.201 1.00 10.24 ? 100 GLN A NE2 1 ATOM 794 N N . ASN A 1 105 ? 11.649 27.375 31.412 1.00 11.17 ? 101 ASN A N 1 ATOM 795 C CA . ASN A 1 105 ? 11.583 28.609 32.221 1.00 11.81 ? 101 ASN A CA 1 ATOM 796 C C . ASN A 1 105 ? 12.374 29.815 31.745 1.00 12.31 ? 101 ASN A C 1 ATOM 797 O O . ASN A 1 105 ? 12.154 30.898 32.258 1.00 12.78 ? 101 ASN A O 1 ATOM 798 C CB . ASN A 1 105 ? 11.951 28.285 33.664 1.00 13.17 ? 101 ASN A CB 1 ATOM 799 C CG . ASN A 1 105 ? 13.247 27.508 33.742 1.00 13.05 ? 101 ASN A CG 1 ATOM 800 O OD1 . ASN A 1 105 ? 14.409 28.076 33.514 1.00 16.21 ? 101 ASN A OD1 1 ATOM 801 N ND2 . ASN A 1 105 ? 13.123 26.236 34.004 1.00 10.51 ? 101 ASN A ND2 1 ATOM 802 N N . ASN A 1 106 ? 13.289 29.638 30.781 1.00 12.02 ? 102 ASN A N 1 ATOM 803 C CA . ASN A 1 106 ? 13.978 30.843 30.251 1.00 13.09 ? 102 ASN A CA 1 ATOM 804 C C . ASN A 1 106 ? 13.081 31.580 29.261 1.00 12.45 ? 102 ASN A C 1 ATOM 805 O O . ASN A 1 106 ? 13.441 32.705 28.857 1.00 13.73 ? 102 ASN A O 1 ATOM 806 C CB . ASN A 1 106 ? 15.262 30.443 29.489 1.00 12.23 ? 102 ASN A CB 1 ATOM 807 C CG . ASN A 1 106 ? 16.438 30.085 30.419 1.00 14.21 ? 102 ASN A CG 1 ATOM 808 O OD1 . ASN A 1 106 ? 16.931 28.953 30.359 1.00 17.18 ? 102 ASN A OD1 1 ATOM 809 N ND2 . ASN A 1 106 ? 16.867 31.008 31.231 1.00 11.17 ? 102 ASN A ND2 1 ATOM 810 N N . VAL A 1 107 ? 11.979 30.964 28.836 1.00 12.91 ? 103 VAL A N 1 ATOM 811 C CA . VAL A 1 107 ? 11.230 31.477 27.661 1.00 12.31 ? 103 VAL A CA 1 ATOM 812 C C . VAL A 1 107 ? 9.998 32.269 28.090 1.00 12.07 ? 103 VAL A C 1 ATOM 813 O O . VAL A 1 107 ? 9.203 31.813 28.904 1.00 13.63 ? 103 VAL A O 1 ATOM 814 C CB . VAL A 1 107 ? 10.810 30.275 26.784 1.00 10.95 ? 103 VAL A CB 1 ATOM 815 C CG1 . VAL A 1 107 ? 9.945 30.738 25.601 1.00 12.62 ? 103 VAL A CG1 1 ATOM 816 C CG2 . VAL A 1 107 ? 12.081 29.556 26.244 1.00 13.36 ? 103 VAL A CG2 1 ATOM 817 N N . TYR A 1 108 ? 9.865 33.477 27.519 1.00 13.32 ? 104 TYR A N 1 ATOM 818 C CA . TYR A 1 108 ? 8.723 34.312 27.807 1.00 13.87 ? 104 TYR A CA 1 ATOM 819 C C . TYR A 1 108 ? 7.442 33.590 27.365 1.00 14.01 ? 104 TYR A C 1 ATOM 820 O O . TYR A 1 108 ? 7.368 33.041 26.245 1.00 14.86 ? 104 TYR A O 1 ATOM 821 C CB . TYR A 1 108 ? 8.879 35.659 27.027 1.00 13.83 ? 104 TYR A CB 1 ATOM 822 C CG . TYR A 1 108 ? 7.720 36.551 27.314 1.00 16.34 ? 104 TYR A CG 1 ATOM 823 C CD1 . TYR A 1 108 ? 7.738 37.427 28.394 1.00 18.05 ? 104 TYR A CD1 1 ATOM 824 C CD2 . TYR A 1 108 ? 6.635 36.515 26.458 1.00 21.21 ? 104 TYR A CD2 1 ATOM 825 C CE1 . TYR A 1 108 ? 6.588 38.277 28.639 1.00 19.45 ? 104 TYR A CE1 1 ATOM 826 C CE2 . TYR A 1 108 ? 5.516 37.330 26.680 1.00 23.04 ? 104 TYR A CE2 1 ATOM 827 C CZ . TYR A 1 108 ? 5.522 38.179 27.762 1.00 20.88 ? 104 TYR A CZ 1 ATOM 828 O OH . TYR A 1 108 ? 4.372 38.983 27.888 1.00 29.34 ? 104 TYR A OH 1 ATOM 829 N N . GLY A 1 109 ? 6.419 33.560 28.244 1.00 13.23 ? 105 GLY A N 1 ATOM 830 C CA . GLY A 1 109 ? 5.160 32.918 27.862 1.00 13.57 ? 105 GLY A CA 1 ATOM 831 C C . GLY A 1 109 ? 5.104 31.406 28.106 1.00 13.29 ? 105 GLY A C 1 ATOM 832 O O . GLY A 1 109 ? 4.051 30.781 27.889 1.00 15.61 ? 105 GLY A O 1 ATOM 833 N N . ALA A 1 110 ? 6.215 30.796 28.562 1.00 11.92 ? 106 ALA A N 1 ATOM 834 C CA . ALA A 1 110 ? 6.196 29.354 28.907 1.00 12.08 ? 106 ALA A CA 1 ATOM 835 C C . ALA A 1 110 ? 5.479 29.178 30.255 1.00 11.37 ? 106 ALA A C 1 ATOM 836 O O . ALA A 1 110 ? 5.661 29.989 31.183 1.00 12.93 ? 106 ALA A O 1 ATOM 837 C CB . ALA A 1 110 ? 7.643 28.839 29.083 1.00 13.25 ? 106 ALA A CB 1 ATOM 838 N N . THR A 1 111 ? 4.751 28.071 30.397 1.00 12.22 ? 107 THR A N 1 ATOM 839 C CA . THR A 1 111 ? 4.160 27.732 31.708 1.00 11.58 ? 107 THR A CA 1 ATOM 840 C C . THR A 1 111 ? 5.267 27.506 32.740 1.00 12.42 ? 107 THR A C 1 ATOM 841 O O . THR A 1 111 ? 6.243 26.784 32.450 1.00 12.14 ? 107 THR A O 1 ATOM 842 C CB . THR A 1 111 ? 3.389 26.427 31.547 1.00 12.45 ? 107 THR A CB 1 ATOM 843 O OG1 . THR A 1 111 ? 2.457 26.588 30.449 1.00 13.31 ? 107 THR A OG1 1 ATOM 844 C CG2 . THR A 1 111 ? 2.639 26.109 32.876 1.00 12.61 ? 107 THR A CG2 1 ATOM 845 N N . ILE A 1 112 ? 5.127 28.121 33.921 1.00 11.13 ? 108 ILE A N 1 ATOM 846 C CA . ILE A 1 112 ? 6.152 27.931 34.977 1.00 10.47 ? 108 ILE A CA 1 ATOM 847 C C . ILE A 1 112 ? 5.533 27.085 36.082 1.00 11.90 ? 108 ILE A C 1 ATOM 848 O O . ILE A 1 112 ? 4.512 27.483 36.707 1.00 12.65 ? 108 ILE A O 1 ATOM 849 C CB . ILE A 1 112 ? 6.635 29.286 35.557 1.00 11.29 ? 108 ILE A CB 1 ATOM 850 C CG1 . ILE A 1 112 ? 7.172 30.199 34.427 1.00 11.49 ? 108 ILE A CG1 1 ATOM 851 C CG2 . ILE A 1 112 ? 7.724 29.032 36.616 1.00 10.97 ? 108 ILE A CG2 1 ATOM 852 C CD1 . ILE A 1 112 ? 8.419 29.616 33.639 1.00 12.71 ? 108 ILE A CD1 1 ATOM 853 N N . PHE A 1 113 ? 6.069 25.884 36.230 1.00 12.36 ? 109 PHE A N 1 ATOM 854 C CA . PHE A 1 113 ? 5.537 24.935 37.263 1.00 12.30 ? 109 PHE A CA 1 ATOM 855 C C . PHE A 1 113 ? 6.184 25.228 38.603 1.00 12.77 ? 109 PHE A C 1 ATOM 856 O O . PHE A 1 113 ? 7.220 25.884 38.681 1.00 12.69 ? 109 PHE A O 1 ATOM 857 C CB . PHE A 1 113 ? 5.852 23.505 36.837 1.00 13.25 ? 109 PHE A CB 1 ATOM 858 C CG . PHE A 1 113 ? 5.121 23.093 35.600 1.00 11.79 ? 109 PHE A CG 1 ATOM 859 C CD1 . PHE A 1 113 ? 3.827 22.584 35.691 1.00 13.70 ? 109 PHE A CD1 1 ATOM 860 C CD2 . PHE A 1 113 ? 5.693 23.300 34.337 1.00 13.73 ? 109 PHE A CD2 1 ATOM 861 C CE1 . PHE A 1 113 ? 3.107 22.213 34.546 1.00 14.27 ? 109 PHE A CE1 1 ATOM 862 C CE2 . PHE A 1 113 ? 4.987 22.948 33.145 1.00 14.08 ? 109 PHE A CE2 1 ATOM 863 C CZ . PHE A 1 113 ? 3.669 22.422 33.258 1.00 13.79 ? 109 PHE A CZ 1 ATOM 864 N N . PRO A 1 114 ? 5.565 24.749 39.704 1.00 11.41 ? 110 PRO A N 1 ATOM 865 C CA . PRO A 1 114 ? 6.244 24.863 41.001 1.00 12.35 ? 110 PRO A CA 1 ATOM 866 C C . PRO A 1 114 ? 7.669 24.294 40.951 1.00 11.37 ? 110 PRO A C 1 ATOM 867 O O . PRO A 1 114 ? 7.869 23.258 40.289 1.00 12.16 ? 110 PRO A O 1 ATOM 868 C CB . PRO A 1 114 ? 5.354 23.994 41.962 1.00 13.63 ? 110 PRO A CB 1 ATOM 869 C CG . PRO A 1 114 ? 4.008 24.072 41.302 1.00 12.06 ? 110 PRO A CG 1 ATOM 870 C CD . PRO A 1 114 ? 4.283 23.999 39.796 1.00 12.52 ? 110 PRO A CD 1 ATOM 871 N N . HIS A 1 115 ? 8.598 24.877 41.700 1.00 12.06 ? 111 HIS A N 1 ATOM 872 C CA . HIS A 1 115 ? 9.930 24.257 41.873 1.00 12.63 ? 111 HIS A CA 1 ATOM 873 C C . HIS A 1 115 ? 9.856 22.929 42.648 1.00 12.96 ? 111 HIS A C 1 ATOM 874 O O . HIS A 1 115 ? 8.808 22.577 43.262 1.00 13.23 ? 111 HIS A O 1 ATOM 875 C CB . HIS A 1 115 ? 10.900 25.218 42.573 1.00 12.85 ? 111 HIS A CB 1 ATOM 876 C CG . HIS A 1 115 ? 11.580 26.152 41.621 1.00 11.84 ? 111 HIS A CG 1 ATOM 877 N ND1 . HIS A 1 115 ? 12.405 25.692 40.610 1.00 13.26 ? 111 HIS A ND1 1 ATOM 878 C CD2 . HIS A 1 115 ? 11.587 27.499 41.555 1.00 13.61 ? 111 HIS A CD2 1 ATOM 879 C CE1 . HIS A 1 115 ? 12.906 26.738 39.964 1.00 12.76 ? 111 HIS A CE1 1 ATOM 880 N NE2 . HIS A 1 115 ? 12.438 27.847 40.521 1.00 12.73 ? 111 HIS A NE2 1 ATOM 881 N N . ASN A 1 116 ? 10.930 22.173 42.531 1.00 13.53 ? 112 ASN A N 1 ATOM 882 C CA . ASN A 1 116 ? 10.963 20.790 43.039 1.00 13.48 ? 112 ASN A CA 1 ATOM 883 C C . ASN A 1 116 ? 10.571 20.593 44.495 1.00 13.71 ? 112 ASN A C 1 ATOM 884 O O . ASN A 1 116 ? 9.863 19.608 44.773 1.00 14.67 ? 112 ASN A O 1 ATOM 885 C CB . ASN A 1 116 ? 12.353 20.181 42.819 1.00 12.51 ? 112 ASN A CB 1 ATOM 886 C CG . ASN A 1 116 ? 12.614 19.825 41.350 1.00 13.90 ? 112 ASN A CG 1 ATOM 887 O OD1 . ASN A 1 116 ? 13.746 19.364 40.998 1.00 17.94 ? 112 ASN A OD1 1 ATOM 888 N ND2 . ASN A 1 116 ? 11.627 19.955 40.518 1.00 10.44 ? 112 ASN A ND2 1 ATOM 889 N N . VAL A 1 117 ? 10.973 21.504 45.391 1.00 13.31 ? 113 VAL A N 1 ATOM 890 C CA . VAL A 1 117 ? 10.641 21.258 46.830 1.00 14.54 ? 113 VAL A CA 1 ATOM 891 C C . VAL A 1 117 ? 9.098 21.189 46.966 1.00 15.73 ? 113 VAL A C 1 ATOM 892 O O . VAL A 1 117 ? 8.554 20.271 47.618 1.00 15.52 ? 113 VAL A O 1 ATOM 893 C CB . VAL A 1 117 ? 11.275 22.305 47.727 1.00 15.56 ? 113 VAL A CB 1 ATOM 894 C CG1 . VAL A 1 117 ? 10.793 23.742 47.347 1.00 15.21 ? 113 VAL A CG1 1 ATOM 895 C CG2 . VAL A 1 117 ? 10.926 21.996 49.206 1.00 17.17 ? 113 VAL A CG2 1 ATOM 896 N N . GLY A 1 118 ? 8.384 22.112 46.340 1.00 14.77 ? 114 GLY A N 1 ATOM 897 C CA . GLY A 1 118 ? 6.905 22.046 46.342 1.00 13.68 ? 114 GLY A CA 1 ATOM 898 C C . GLY A 1 118 ? 6.375 20.767 45.690 1.00 14.87 ? 114 GLY A C 1 ATOM 899 O O . GLY A 1 118 ? 5.355 20.175 46.153 1.00 14.51 ? 114 GLY A O 1 ATOM 900 N N . LEU A 1 119 ? 6.969 20.318 44.576 1.00 13.48 ? 115 LEU A N 1 ATOM 901 C CA . LEU A 1 119 ? 6.528 19.054 44.000 1.00 13.30 ? 115 LEU A CA 1 ATOM 902 C C . LEU A 1 119 ? 6.751 17.885 44.984 1.00 14.81 ? 115 LEU A C 1 ATOM 903 O O . LEU A 1 119 ? 5.937 16.979 45.016 1.00 15.12 ? 115 LEU A O 1 ATOM 904 C CB . LEU A 1 119 ? 7.233 18.795 42.661 1.00 13.84 ? 115 LEU A CB 1 ATOM 905 C CG . LEU A 1 119 ? 6.922 19.895 41.631 1.00 12.50 ? 115 LEU A CG 1 ATOM 906 C CD1 . LEU A 1 119 ? 7.668 19.531 40.304 1.00 13.84 ? 115 LEU A CD1 1 ATOM 907 C CD2 . LEU A 1 119 ? 5.391 20.064 41.362 1.00 13.88 ? 115 LEU A CD2 1 ATOM 908 N N . GLY A 1 120 ? 7.822 17.910 45.747 1.00 14.81 ? 116 GLY A N 1 ATOM 909 C CA . GLY A 1 120 ? 8.032 16.886 46.786 1.00 15.06 ? 116 GLY A CA 1 ATOM 910 C C . GLY A 1 120 ? 6.838 16.900 47.763 1.00 16.28 ? 116 GLY A C 1 ATOM 911 O O . GLY A 1 120 ? 6.396 15.828 48.220 1.00 16.15 ? 116 GLY A O 1 ATOM 912 N N . ALA A 1 121 ? 6.353 18.091 48.095 1.00 15.67 ? 117 ALA A N 1 ATOM 913 C CA . ALA A 1 121 ? 5.232 18.195 49.031 1.00 16.39 ? 117 ALA A CA 1 ATOM 914 C C . ALA A 1 121 ? 3.980 17.505 48.526 1.00 16.52 ? 117 ALA A C 1 ATOM 915 O O . ALA A 1 121 ? 3.085 17.181 49.336 1.00 16.59 ? 117 ALA A O 1 ATOM 916 C CB . ALA A 1 121 ? 4.947 19.693 49.356 1.00 15.38 ? 117 ALA A CB 1 ATOM 917 N N . THR A 1 122 ? 3.828 17.342 47.211 1.00 16.19 ? 118 THR A N 1 ATOM 918 C CA . THR A 1 122 ? 2.602 16.697 46.647 1.00 15.81 ? 118 THR A CA 1 ATOM 919 C C . THR A 1 122 ? 2.610 15.165 46.869 1.00 17.24 ? 118 THR A C 1 ATOM 920 O O . THR A 1 122 ? 1.558 14.535 46.795 1.00 19.18 ? 118 THR A O 1 ATOM 921 C CB . THR A 1 122 ? 2.418 16.935 45.141 1.00 16.88 ? 118 THR A CB 1 ATOM 922 O OG1 . THR A 1 122 ? 3.406 16.168 44.383 1.00 16.66 ? 118 THR A OG1 1 ATOM 923 C CG2 . THR A 1 122 ? 2.583 18.455 44.802 1.00 15.44 ? 118 THR A CG2 1 ATOM 924 N N . ARG A 1 123 ? 3.781 14.584 47.077 1.00 18.22 ? 119 ARG A N 1 ATOM 925 C CA . ARG A 1 123 ? 3.877 13.102 47.088 1.00 18.01 ? 119 ARG A CA 1 ATOM 926 C C . ARG A 1 123 ? 3.131 12.466 45.913 1.00 20.04 ? 119 ARG A C 1 ATOM 927 O O . ARG A 1 123 ? 2.564 11.366 46.050 1.00 20.86 ? 119 ARG A O 1 ATOM 928 C CB . ARG A 1 123 ? 3.328 12.547 48.437 1.00 19.25 ? 119 ARG A CB 1 ATOM 929 C CG . ARG A 1 123 ? 3.974 13.105 49.625 1.00 20.44 ? 119 ARG A CG 1 ATOM 930 C CD . ARG A 1 123 ? 5.459 12.802 49.732 1.00 21.71 ? 119 ARG A CD 1 ATOM 931 N NE . ARG A 1 123 ? 5.846 12.936 51.140 1.00 22.15 ? 119 ARG A NE 1 ATOM 932 C CZ . ARG A 1 123 ? 6.041 14.092 51.789 1.00 22.51 ? 119 ARG A CZ 1 ATOM 933 N NH1 . ARG A 1 123 ? 6.019 15.293 51.119 1.00 18.95 ? 119 ARG A NH1 1 ATOM 934 N NH2 . ARG A 1 123 ? 6.323 14.063 53.102 1.00 22.16 ? 119 ARG A NH2 1 ATOM 935 N N . ASP A 1 124 ? 3.128 13.125 44.738 1.00 18.60 ? 120 ASP A N 1 ATOM 936 C CA . ASP A 1 124 ? 2.382 12.660 43.587 1.00 18.43 ? 120 ASP A CA 1 ATOM 937 C C . ASP A 1 124 ? 3.325 12.468 42.377 1.00 19.92 ? 120 ASP A C 1 ATOM 938 O O . ASP A 1 124 ? 3.408 13.380 41.518 1.00 18.11 ? 120 ASP A O 1 ATOM 939 C CB . ASP A 1 124 ? 1.281 13.669 43.299 1.00 19.29 ? 120 ASP A CB 1 ATOM 940 C CG . ASP A 1 124 ? 0.239 13.182 42.325 1.00 20.28 ? 120 ASP A CG 1 ATOM 941 O OD1 . ASP A 1 124 ? 0.490 12.250 41.545 1.00 23.92 ? 120 ASP A OD1 1 ATOM 942 O OD2 . ASP A 1 124 ? -0.863 13.800 42.368 1.00 26.08 ? 120 ASP A OD2 1 ATOM 943 N N . PRO A 1 125 ? 3.942 11.274 42.261 1.00 19.91 ? 121 PRO A N 1 ATOM 944 C CA . PRO A 1 125 ? 4.871 11.023 41.124 1.00 19.88 ? 121 PRO A CA 1 ATOM 945 C C . PRO A 1 125 ? 4.181 11.131 39.771 1.00 19.58 ? 121 PRO A C 1 ATOM 946 O O . PRO A 1 125 ? 4.823 11.552 38.793 1.00 19.76 ? 121 PRO A O 1 ATOM 947 C CB . PRO A 1 125 ? 5.371 9.580 41.381 1.00 20.88 ? 121 PRO A CB 1 ATOM 948 C CG . PRO A 1 125 ? 5.316 9.448 42.895 1.00 22.47 ? 121 PRO A CG 1 ATOM 949 C CD . PRO A 1 125 ? 4.008 10.176 43.262 1.00 21.20 ? 121 PRO A CD 1 ATOM 950 N N . TYR A 1 126 ? 2.896 10.773 39.664 1.00 18.39 ? 122 TYR A N 1 ATOM 951 C CA . TYR A 1 126 ? 2.192 10.820 38.399 1.00 18.08 ? 122 TYR A CA 1 ATOM 952 C C . TYR A 1 126 ? 1.961 12.278 37.957 1.00 17.78 ? 122 TYR A C 1 ATOM 953 O O . TYR A 1 126 ? 2.064 12.601 36.791 1.00 17.54 ? 122 TYR A O 1 ATOM 954 C CB . TYR A 1 126 ? 0.827 10.040 38.426 1.00 19.42 ? 122 TYR A CB 1 ATOM 955 C CG . TYR A 1 126 ? 0.179 10.047 37.058 1.00 20.65 ? 122 TYR A CG 1 ATOM 956 C CD1 . TYR A 1 126 ? 0.911 9.660 35.907 1.00 24.41 ? 122 TYR A CD1 1 ATOM 957 C CD2 . TYR A 1 126 ? -1.131 10.509 36.868 1.00 24.51 ? 122 TYR A CD2 1 ATOM 958 C CE1 . TYR A 1 126 ? 0.356 9.718 34.628 1.00 25.28 ? 122 TYR A CE1 1 ATOM 959 C CE2 . TYR A 1 126 ? -1.695 10.549 35.583 1.00 25.65 ? 122 TYR A CE2 1 ATOM 960 C CZ . TYR A 1 126 ? -0.950 10.136 34.471 1.00 26.62 ? 122 TYR A CZ 1 ATOM 961 O OH . TYR A 1 126 ? -1.502 10.189 33.201 1.00 31.04 ? 122 TYR A OH 1 ATOM 962 N N . LEU A 1 127 ? 1.663 13.148 38.911 1.00 16.81 ? 123 LEU A N 1 ATOM 963 C CA . LEU A 1 127 ? 1.622 14.592 38.631 1.00 15.24 ? 123 LEU A CA 1 ATOM 964 C C . LEU A 1 127 ? 2.984 15.048 38.029 1.00 15.58 ? 123 LEU A C 1 ATOM 965 O O . LEU A 1 127 ? 3.001 15.779 37.003 1.00 15.62 ? 123 LEU A O 1 ATOM 966 C CB . LEU A 1 127 ? 1.338 15.346 39.943 1.00 16.31 ? 123 LEU A CB 1 ATOM 967 C CG . LEU A 1 127 ? 1.486 16.870 39.834 1.00 17.14 ? 123 LEU A CG 1 ATOM 968 C CD1 . LEU A 1 127 ? 0.283 17.482 39.113 1.00 20.00 ? 123 LEU A CD1 1 ATOM 969 C CD2 . LEU A 1 127 ? 1.579 17.441 41.236 1.00 20.10 ? 123 LEU A CD2 1 ATOM 970 N N . VAL A 1 128 ? 4.066 14.642 38.680 1.00 16.47 ? 124 VAL A N 1 ATOM 971 C CA . VAL A 1 128 ? 5.425 15.012 38.214 1.00 15.76 ? 124 VAL A CA 1 ATOM 972 C C . VAL A 1 128 ? 5.690 14.445 36.820 1.00 16.62 ? 124 VAL A C 1 ATOM 973 O O . VAL A 1 128 ? 6.234 15.148 35.943 1.00 14.82 ? 124 VAL A O 1 ATOM 974 C CB . VAL A 1 128 ? 6.486 14.677 39.247 1.00 16.04 ? 124 VAL A CB 1 ATOM 975 C CG1 . VAL A 1 128 ? 7.901 14.968 38.672 1.00 16.44 ? 124 VAL A CG1 1 ATOM 976 C CG2 . VAL A 1 128 ? 6.243 15.553 40.509 1.00 18.32 ? 124 VAL A CG2 1 ATOM 977 N N . LYS A 1 129 ? 5.277 13.191 36.580 1.00 15.53 ? 125 LYS A N 1 ATOM 978 C CA . LYS A 1 129 ? 5.394 12.680 35.222 1.00 16.03 ? 125 LYS A CA 1 ATOM 979 C C . LYS A 1 129 ? 4.659 13.555 34.209 1.00 14.84 ? 125 LYS A C 1 ATOM 980 O O . LYS A 1 129 ? 5.185 13.872 33.136 1.00 14.87 ? 125 LYS A O 1 ATOM 981 C CB . LYS A 1 129 ? 4.854 11.217 35.142 1.00 15.74 ? 125 LYS A CB 1 ATOM 982 C CG . LYS A 1 129 ? 5.200 10.556 33.811 1.00 17.46 ? 125 LYS A CG 1 ATOM 983 C CD . LYS A 1 129 ? 4.559 9.173 33.700 1.00 20.59 ? 125 LYS A CD 1 ATOM 984 C CE . LYS A 1 129 ? 4.970 8.554 32.366 1.00 21.25 ? 125 LYS A CE 1 ATOM 985 N NZ . LYS A 1 129 ? 4.354 7.171 32.278 1.00 24.93 ? 125 LYS A NZ 1 ATOM 986 N N . ARG A 1 130 ? 3.408 13.956 34.518 1.00 14.68 ? 126 ARG A N 1 ATOM 987 C CA . ARG A 1 130 ? 2.652 14.777 33.623 1.00 15.00 ? 126 ARG A CA 1 ATOM 988 C C . ARG A 1 130 ? 3.344 16.131 33.407 1.00 13.84 ? 126 ARG A C 1 ATOM 989 O O . ARG A 1 130 ? 3.283 16.671 32.284 1.00 15.07 ? 126 ARG A O 1 ATOM 990 C CB . ARG A 1 130 ? 1.204 14.974 34.163 1.00 15.48 ? 126 ARG A CB 1 ATOM 991 C CG . ARG A 1 130 ? 0.443 13.627 34.132 1.00 17.80 ? 126 ARG A CG 1 ATOM 992 C CD . ARG A 1 130 ? -0.397 13.408 35.441 1.00 31.42 ? 126 ARG A CD 1 ATOM 993 N NE . ARG A 1 130 ? -1.365 14.419 35.464 1.00 30.98 ? 126 ARG A NE 1 ATOM 994 C CZ . ARG A 1 130 ? -1.965 15.052 36.488 1.00 27.46 ? 126 ARG A CZ 1 ATOM 995 N NH1 . ARG A 1 130 ? -1.883 14.751 37.805 1.00 25.08 ? 126 ARG A NH1 1 ATOM 996 N NH2 . ARG A 1 130 ? -2.765 15.996 36.076 1.00 26.47 ? 126 ARG A NH2 1 ATOM 997 N N . ILE A 1 131 ? 3.954 16.651 34.474 1.00 14.51 ? 127 ILE A N 1 ATOM 998 C CA . ILE A 1 131 ? 4.738 17.923 34.336 1.00 13.75 ? 127 ILE A CA 1 ATOM 999 C C . ILE A 1 131 ? 5.913 17.694 33.358 1.00 14.33 ? 127 ILE A C 1 ATOM 1000 O O . ILE A 1 131 ? 6.164 18.531 32.454 1.00 13.45 ? 127 ILE A O 1 ATOM 1001 C CB . ILE A 1 131 ? 5.227 18.414 35.681 1.00 13.47 ? 127 ILE A CB 1 ATOM 1002 C CG1 . ILE A 1 131 ? 4.009 18.939 36.485 1.00 15.05 ? 127 ILE A CG1 1 ATOM 1003 C CG2 . ILE A 1 131 ? 6.274 19.554 35.487 1.00 14.48 ? 127 ILE A CG2 1 ATOM 1004 C CD1 . ILE A 1 131 ? 4.372 19.284 37.927 1.00 13.30 ? 127 ILE A CD1 1 ATOM 1005 N N . GLY A 1 132 ? 6.571 16.546 33.486 1.00 13.91 ? 128 GLY A N 1 ATOM 1006 C CA . GLY A 1 132 ? 7.659 16.213 32.521 1.00 13.69 ? 128 GLY A CA 1 ATOM 1007 C C . GLY A 1 132 ? 7.122 16.180 31.096 1.00 13.88 ? 128 GLY A C 1 ATOM 1008 O O . GLY A 1 132 ? 7.751 16.710 30.141 1.00 13.50 ? 128 GLY A O 1 ATOM 1009 N N . GLU A 1 133 ? 5.941 15.552 30.893 1.00 13.79 ? 129 GLU A N 1 ATOM 1010 C CA . GLU A 1 133 ? 5.310 15.494 29.558 1.00 14.24 ? 129 GLU A CA 1 ATOM 1011 C C . GLU A 1 133 ? 5.017 16.879 28.992 1.00 14.70 ? 129 GLU A C 1 ATOM 1012 O O . GLU A 1 133 ? 5.352 17.177 27.853 1.00 14.57 ? 129 GLU A O 1 ATOM 1013 C CB . GLU A 1 133 ? 4.034 14.611 29.638 1.00 15.92 ? 129 GLU A CB 1 ATOM 1014 C CG . GLU A 1 133 ? 4.418 13.194 30.080 1.00 18.54 ? 129 GLU A CG 1 ATOM 1015 C CD . GLU A 1 133 ? 3.243 12.218 30.216 1.00 28.72 ? 129 GLU A CD 1 ATOM 1016 O OE1 . GLU A 1 133 ? 3.496 10.982 30.170 1.00 28.06 ? 129 GLU A OE1 1 ATOM 1017 O OE2 . GLU A 1 133 ? 2.102 12.699 30.359 1.00 28.17 ? 129 GLU A OE2 1 ATOM 1018 N N . ALA A 1 134 ? 4.451 17.767 29.815 1.00 12.64 ? 130 ALA A N 1 ATOM 1019 C CA . ALA A 1 134 ? 4.144 19.099 29.368 1.00 13.25 ? 130 ALA A CA 1 ATOM 1020 C C . ALA A 1 134 ? 5.416 19.893 29.108 1.00 12.83 ? 130 ALA A C 1 ATOM 1021 O O . ALA A 1 134 ? 5.455 20.665 28.145 1.00 13.41 ? 130 ALA A O 1 ATOM 1022 C CB . ALA A 1 134 ? 3.286 19.798 30.460 1.00 14.46 ? 130 ALA A CB 1 ATOM 1023 N N . THR A 1 135 ? 6.407 19.712 29.994 1.00 13.27 ? 131 THR A N 1 ATOM 1024 C CA . THR A 1 135 ? 7.698 20.438 29.838 1.00 12.62 ? 131 THR A CA 1 ATOM 1025 C C . THR A 1 135 ? 8.350 20.050 28.534 1.00 13.32 ? 131 THR A C 1 ATOM 1026 O O . THR A 1 135 ? 8.774 20.933 27.756 1.00 13.28 ? 131 THR A O 1 ATOM 1027 C CB . THR A 1 135 ? 8.587 20.184 31.002 1.00 13.38 ? 131 THR A CB 1 ATOM 1028 O OG1 . THR A 1 135 ? 7.930 20.669 32.183 1.00 14.13 ? 131 THR A OG1 1 ATOM 1029 C CG2 . THR A 1 135 ? 9.948 20.926 30.861 1.00 13.87 ? 131 THR A CG2 1 ATOM 1030 N N . ALA A 1 136 ? 8.350 18.770 28.212 1.00 13.67 ? 132 ALA A N 1 ATOM 1031 C CA . ALA A 1 136 ? 8.933 18.351 26.898 1.00 14.14 ? 132 ALA A CA 1 ATOM 1032 C C . ALA A 1 136 ? 8.262 19.034 25.721 1.00 13.89 ? 132 ALA A C 1 ATOM 1033 O O . ALA A 1 136 ? 8.935 19.466 24.771 1.00 14.59 ? 132 ALA A O 1 ATOM 1034 C CB . ALA A 1 136 ? 8.824 16.843 26.731 1.00 15.04 ? 132 ALA A CB 1 ATOM 1035 N N . LEU A 1 137 ? 6.919 19.124 25.755 1.00 13.79 ? 133 LEU A N 1 ATOM 1036 C CA . LEU A 1 137 ? 6.210 19.782 24.671 1.00 13.80 ? 133 LEU A CA 1 ATOM 1037 C C . LEU A 1 137 ? 6.594 21.244 24.557 1.00 13.77 ? 133 LEU A C 1 ATOM 1038 O O . LEU A 1 137 ? 6.774 21.765 23.453 1.00 14.41 ? 133 LEU A O 1 ATOM 1039 C CB . LEU A 1 137 ? 4.683 19.669 24.845 1.00 14.86 ? 133 LEU A CB 1 ATOM 1040 C CG . LEU A 1 137 ? 4.220 18.235 24.712 1.00 17.04 ? 133 LEU A CG 1 ATOM 1041 C CD1 . LEU A 1 137 ? 2.722 18.248 25.117 1.00 19.70 ? 133 LEU A CD1 1 ATOM 1042 C CD2 . LEU A 1 137 ? 4.301 17.767 23.250 1.00 19.70 ? 133 LEU A CD2 1 ATOM 1043 N N . GLU A 1 138 ? 6.735 21.926 25.696 1.00 12.75 ? 134 GLU A N 1 ATOM 1044 C CA . GLU A 1 138 ? 7.046 23.374 25.613 1.00 12.49 ? 134 GLU A CA 1 ATOM 1045 C C . GLU A 1 138 ? 8.528 23.642 25.251 1.00 13.53 ? 134 GLU A C 1 ATOM 1046 O O . GLU A 1 138 ? 8.845 24.717 24.662 1.00 12.94 ? 134 GLU A O 1 ATOM 1047 C CB . GLU A 1 138 ? 6.659 24.095 26.918 1.00 12.76 ? 134 GLU A CB 1 ATOM 1048 C CG . GLU A 1 138 ? 5.114 23.988 27.152 1.00 13.19 ? 134 GLU A CG 1 ATOM 1049 C CD . GLU A 1 138 ? 4.534 25.104 28.008 1.00 15.29 ? 134 GLU A CD 1 ATOM 1050 O OE1 . GLU A 1 138 ? 5.141 26.181 28.202 1.00 13.70 ? 134 GLU A OE1 1 ATOM 1051 O OE2 . GLU A 1 138 ? 3.357 24.881 28.447 1.00 15.02 ? 134 GLU A OE2 1 ATOM 1052 N N . VAL A 1 139 ? 9.388 22.695 25.601 1.00 12.50 ? 135 VAL A N 1 ATOM 1053 C CA . VAL A 1 139 ? 10.802 22.779 25.169 1.00 11.86 ? 135 VAL A CA 1 ATOM 1054 C C . VAL A 1 139 ? 10.840 22.531 23.650 1.00 12.50 ? 135 VAL A C 1 ATOM 1055 O O . VAL A 1 139 ? 11.487 23.324 22.891 1.00 12.97 ? 135 VAL A O 1 ATOM 1056 C CB . VAL A 1 139 ? 11.658 21.771 25.963 1.00 10.92 ? 135 VAL A CB 1 ATOM 1057 C CG1 . VAL A 1 139 ? 13.121 21.734 25.401 1.00 12.76 ? 135 VAL A CG1 1 ATOM 1058 C CG2 . VAL A 1 139 ? 11.706 22.181 27.409 1.00 13.26 ? 135 VAL A CG2 1 ATOM 1059 N N . ARG A 1 140 ? 10.125 21.510 23.176 1.00 12.97 ? 136 ARG A N 1 ATOM 1060 C CA . ARG A 1 140 ? 10.127 21.268 21.708 1.00 14.16 ? 136 ARG A CA 1 ATOM 1061 C C . ARG A 1 140 ? 9.433 22.388 20.934 1.00 13.47 ? 136 ARG A C 1 ATOM 1062 O O . ARG A 1 140 ? 9.714 22.656 19.769 1.00 14.14 ? 136 ARG A O 1 ATOM 1063 C CB . ARG A 1 140 ? 9.524 19.887 21.362 1.00 13.18 ? 136 ARG A CB 1 ATOM 1064 C CG . ARG A 1 140 ? 10.463 18.711 21.695 1.00 14.70 ? 136 ARG A CG 1 ATOM 1065 C CD . ARG A 1 140 ? 11.624 18.701 20.622 1.00 15.51 ? 136 ARG A CD 1 ATOM 1066 N NE . ARG A 1 140 ? 12.340 17.454 20.791 1.00 15.23 ? 136 ARG A NE 1 ATOM 1067 C CZ . ARG A 1 140 ? 13.124 16.928 19.836 1.00 16.07 ? 136 ARG A CZ 1 ATOM 1068 N NH1 . ARG A 1 140 ? 13.338 17.602 18.741 1.00 15.45 ? 136 ARG A NH1 1 ATOM 1069 N NH2 . ARG A 1 140 ? 13.671 15.717 20.019 1.00 17.51 ? 136 ARG A NH2 1 ATOM 1070 N N . ALA A 1 141 ? 8.531 23.131 21.628 1.00 13.40 ? 137 ALA A N 1 ATOM 1071 C CA . ALA A 1 141 ? 7.898 24.290 20.984 1.00 14.65 ? 137 ALA A CA 1 ATOM 1072 C C . ALA A 1 141 ? 8.894 25.317 20.560 1.00 14.60 ? 137 ALA A C 1 ATOM 1073 O O . ALA A 1 141 ? 8.656 26.138 19.659 1.00 14.53 ? 137 ALA A O 1 ATOM 1074 C CB . ALA A 1 141 ? 6.894 24.951 21.996 1.00 14.84 ? 137 ALA A CB 1 ATOM 1075 N N . THR A 1 142 ? 10.015 25.345 21.297 1.00 14.11 ? 138 THR A N 1 ATOM 1076 C CA . THR A 1 142 ? 11.087 26.331 21.056 1.00 13.64 ? 138 THR A CA 1 ATOM 1077 C C . THR A 1 142 ? 12.235 25.708 20.248 1.00 13.41 ? 138 THR A C 1 ATOM 1078 O O . THR A 1 142 ? 13.295 26.325 20.060 1.00 14.95 ? 138 THR A O 1 ATOM 1079 C CB . THR A 1 142 ? 11.644 26.937 22.391 1.00 14.27 ? 138 THR A CB 1 ATOM 1080 O OG1 . THR A 1 142 ? 12.235 25.895 23.202 1.00 13.81 ? 138 THR A OG1 1 ATOM 1081 C CG2 . THR A 1 142 ? 10.518 27.540 23.175 1.00 15.44 ? 138 THR A CG2 1 ATOM 1082 N N . GLY A 1 143 ? 12.016 24.476 19.752 1.00 12.24 ? 139 GLY A N 1 ATOM 1083 C CA . GLY A 1 143 ? 13.061 23.808 18.889 1.00 14.42 ? 139 GLY A CA 1 ATOM 1084 C C . GLY A 1 143 ? 14.178 23.105 19.646 1.00 14.63 ? 139 GLY A C 1 ATOM 1085 O O . GLY A 1 143 ? 15.121 22.614 19.046 1.00 17.64 ? 139 GLY A O 1 ATOM 1086 N N . ILE A 1 144 ? 14.097 23.108 20.964 1.00 13.27 ? 140 ILE A N 1 ATOM 1087 C CA . ILE A 1 144 ? 15.182 22.564 21.793 1.00 12.50 ? 140 ILE A CA 1 ATOM 1088 C C . ILE A 1 144 ? 14.912 21.108 22.110 1.00 12.91 ? 140 ILE A C 1 ATOM 1089 O O . ILE A 1 144 ? 13.749 20.689 22.306 1.00 13.79 ? 140 ILE A O 1 ATOM 1090 C CB . ILE A 1 144 ? 15.340 23.430 23.038 1.00 12.25 ? 140 ILE A CB 1 ATOM 1091 C CG1 . ILE A 1 144 ? 15.861 24.791 22.573 1.00 13.04 ? 140 ILE A CG1 1 ATOM 1092 C CG2 . ILE A 1 144 ? 16.299 22.800 24.080 1.00 12.34 ? 140 ILE A CG2 1 ATOM 1093 C CD1 . ILE A 1 144 ? 15.945 25.893 23.615 1.00 13.71 ? 140 ILE A CD1 1 ATOM 1094 N N . GLN A 1 145 ? 15.988 20.326 22.125 1.00 12.63 ? 141 GLN A N 1 ATOM 1095 C CA . GLN A 1 145 ? 15.833 18.852 22.197 1.00 12.15 ? 141 GLN A CA 1 ATOM 1096 C C . GLN A 1 145 ? 16.305 18.242 23.495 1.00 13.16 ? 141 GLN A C 1 ATOM 1097 O O . GLN A 1 145 ? 16.227 17.036 23.649 1.00 13.60 ? 141 GLN A O 1 ATOM 1098 C CB . GLN A 1 145 ? 16.623 18.171 21.064 1.00 13.32 ? 141 GLN A CB 1 ATOM 1099 C CG . GLN A 1 145 ? 16.428 18.791 19.661 1.00 14.05 ? 141 GLN A CG 1 ATOM 1100 C CD . GLN A 1 145 ? 17.505 19.786 19.263 1.00 14.20 ? 141 GLN A CD 1 ATOM 1101 O OE1 . GLN A 1 145 ? 18.227 20.312 20.120 1.00 15.50 ? 141 GLN A OE1 1 ATOM 1102 N NE2 . GLN A 1 145 ? 17.564 20.098 17.972 1.00 17.19 ? 141 GLN A NE2 1 ATOM 1103 N N . TYR A 1 146 ? 16.782 19.033 24.455 1.00 12.39 ? 142 TYR A N 1 ATOM 1104 C CA . TYR A 1 146 ? 17.517 18.454 25.611 1.00 12.20 ? 142 TYR A CA 1 ATOM 1105 C C . TYR A 1 146 ? 17.345 19.402 26.818 1.00 12.20 ? 142 TYR A C 1 ATOM 1106 O O . TYR A 1 146 ? 17.596 20.599 26.720 1.00 12.43 ? 142 TYR A O 1 ATOM 1107 C CB . TYR A 1 146 ? 19.009 18.386 25.146 1.00 12.00 ? 142 TYR A CB 1 ATOM 1108 C CG . TYR A 1 146 ? 20.011 17.972 26.181 1.00 12.39 ? 142 TYR A CG 1 ATOM 1109 C CD1 . TYR A 1 146 ? 19.678 17.136 27.271 1.00 13.22 ? 142 TYR A CD1 1 ATOM 1110 C CD2 . TYR A 1 146 ? 21.361 18.300 25.996 1.00 13.73 ? 142 TYR A CD2 1 ATOM 1111 C CE1 . TYR A 1 146 ? 20.653 16.736 28.201 1.00 13.64 ? 142 TYR A CE1 1 ATOM 1112 C CE2 . TYR A 1 146 ? 22.353 17.909 26.935 1.00 13.45 ? 142 TYR A CE2 1 ATOM 1113 C CZ . TYR A 1 146 ? 21.989 17.118 28.003 1.00 13.09 ? 142 TYR A CZ 1 ATOM 1114 O OH . TYR A 1 146 ? 22.941 16.734 28.916 1.00 16.10 ? 142 TYR A OH 1 ATOM 1115 N N . ALA A 1 147 ? 16.819 18.861 27.935 1.00 12.80 ? 143 ALA A N 1 ATOM 1116 C CA . ALA A 1 147 ? 16.665 19.627 29.150 1.00 12.40 ? 143 ALA A CA 1 ATOM 1117 C C . ALA A 1 147 ? 17.576 19.134 30.239 1.00 11.40 ? 143 ALA A C 1 ATOM 1118 O O . ALA A 1 147 ? 17.656 17.907 30.481 1.00 12.68 ? 143 ALA A O 1 ATOM 1119 C CB . ALA A 1 147 ? 15.187 19.435 29.629 1.00 14.24 ? 143 ALA A CB 1 ATOM 1120 N N . PHE A 1 148 ? 18.203 20.077 30.942 1.00 12.21 ? 144 PHE A N 1 ATOM 1121 C CA . PHE A 1 148 ? 19.121 19.714 32.017 1.00 12.19 ? 144 PHE A CA 1 ATOM 1122 C C . PHE A 1 148 ? 18.277 19.490 33.311 1.00 12.51 ? 144 PHE A C 1 ATOM 1123 O O . PHE A 1 148 ? 18.411 20.259 34.273 1.00 13.07 ? 144 PHE A O 1 ATOM 1124 C CB . PHE A 1 148 ? 20.173 20.814 32.258 1.00 12.94 ? 144 PHE A CB 1 ATOM 1125 C CG . PHE A 1 148 ? 21.046 21.137 31.059 1.00 12.51 ? 144 PHE A CG 1 ATOM 1126 C CD1 . PHE A 1 148 ? 21.812 20.158 30.414 1.00 15.69 ? 144 PHE A CD1 1 ATOM 1127 C CD2 . PHE A 1 148 ? 21.161 22.466 30.651 1.00 12.56 ? 144 PHE A CD2 1 ATOM 1128 C CE1 . PHE A 1 148 ? 22.668 20.486 29.307 1.00 15.14 ? 144 PHE A CE1 1 ATOM 1129 C CE2 . PHE A 1 148 ? 21.995 22.823 29.543 1.00 13.71 ? 144 PHE A CE2 1 ATOM 1130 C CZ . PHE A 1 148 ? 22.749 21.816 28.874 1.00 14.44 ? 144 PHE A CZ 1 ATOM 1131 N N . ALA A 1 149 ? 17.501 18.423 33.314 1.00 13.62 ? 145 ALA A N 1 ATOM 1132 C CA . ALA A 1 149 ? 16.618 18.099 34.443 1.00 13.02 ? 145 ALA A CA 1 ATOM 1133 C C . ALA A 1 149 ? 16.342 16.583 34.359 1.00 12.28 ? 145 ALA A C 1 ATOM 1134 O O . ALA A 1 149 ? 16.295 16.022 33.266 1.00 13.51 ? 145 ALA A O 1 ATOM 1135 C CB . ALA A 1 149 ? 15.280 18.866 34.260 1.00 13.21 ? 145 ALA A CB 1 ATOM 1136 N N . PRO A 1 150 ? 16.015 15.946 35.496 1.00 14.32 ? 146 PRO A N 1 ATOM 1137 C CA . PRO A 1 150 ? 15.842 16.506 36.811 1.00 13.94 ? 146 PRO A CA 1 ATOM 1138 C C . PRO A 1 150 ? 17.073 16.702 37.659 1.00 14.44 ? 146 PRO A C 1 ATOM 1139 O O . PRO A 1 150 ? 18.003 15.859 37.632 1.00 15.90 ? 146 PRO A O 1 ATOM 1140 C CB . PRO A 1 150 ? 14.968 15.439 37.548 1.00 14.69 ? 146 PRO A CB 1 ATOM 1141 C CG . PRO A 1 150 ? 15.439 14.140 36.938 1.00 14.50 ? 146 PRO A CG 1 ATOM 1142 C CD . PRO A 1 150 ? 15.673 14.504 35.446 1.00 14.79 ? 146 PRO A CD 1 ATOM 1143 N N . CYS A 1 151 ? 17.036 17.727 38.505 1.00 14.35 ? 147 CYS A N 1 ATOM 1144 C CA . CYS A 1 151 ? 17.974 17.784 39.626 1.00 14.14 ? 147 CYS A CA 1 ATOM 1145 C C . CYS A 1 151 ? 17.445 16.792 40.687 1.00 14.89 ? 147 CYS A C 1 ATOM 1146 O O . CYS A 1 151 ? 16.342 16.984 41.247 1.00 15.08 ? 147 CYS A O 1 ATOM 1147 C CB . CYS A 1 151 ? 18.019 19.198 40.209 1.00 14.10 ? 147 CYS A CB 1 ATOM 1148 S SG . CYS A 1 151 ? 19.130 19.219 41.659 1.00 16.49 ? 147 CYS A SG 1 ATOM 1149 N N . ILE A 1 152 ? 18.183 15.700 40.875 1.00 14.63 ? 148 ILE A N 1 ATOM 1150 C CA . ILE A 1 152 ? 17.873 14.663 41.895 1.00 15.61 ? 148 ILE A CA 1 ATOM 1151 C C . ILE A 1 152 ? 18.798 14.807 43.101 1.00 15.58 ? 148 ILE A C 1 ATOM 1152 O O . ILE A 1 152 ? 18.988 13.814 43.868 1.00 16.15 ? 148 ILE A O 1 ATOM 1153 C CB . ILE A 1 152 ? 17.839 13.259 41.276 1.00 13.92 ? 148 ILE A CB 1 ATOM 1154 C CG1 . ILE A 1 152 ? 19.205 12.945 40.573 1.00 16.64 ? 148 ILE A CG1 1 ATOM 1155 C CG2 . ILE A 1 152 ? 16.680 13.127 40.329 1.00 15.50 ? 148 ILE A CG2 1 ATOM 1156 C CD1 . ILE A 1 152 ? 19.259 11.422 40.235 1.00 16.69 ? 148 ILE A CD1 1 ATOM 1157 N N . ALA A 1 153 ? 19.261 16.034 43.402 1.00 15.46 ? 149 ALA A N 1 ATOM 1158 C CA . ALA A 1 153 ? 19.949 16.318 44.669 1.00 16.07 ? 149 ALA A CA 1 ATOM 1159 C C . ALA A 1 153 ? 19.013 15.956 45.840 1.00 16.90 ? 149 ALA A C 1 ATOM 1160 O O . ALA A 1 153 ? 17.784 16.124 45.747 1.00 16.66 ? 149 ALA A O 1 ATOM 1161 C CB . ALA A 1 153 ? 20.330 17.786 44.768 1.00 17.15 ? 149 ALA A CB 1 ATOM 1162 N N . VAL A 1 154 ? 19.608 15.458 46.924 1.00 17.66 ? 150 VAL A N 1 ATOM 1163 C CA . VAL A 1 154 ? 18.871 15.162 48.167 1.00 17.87 ? 150 VAL A CA 1 ATOM 1164 C C . VAL A 1 154 ? 19.408 16.213 49.120 1.00 18.49 ? 150 VAL A C 1 ATOM 1165 O O . VAL A 1 154 ? 20.486 16.084 49.715 1.00 17.92 ? 150 VAL A O 1 ATOM 1166 C CB . VAL A 1 154 ? 19.125 13.732 48.646 1.00 16.81 ? 150 VAL A CB 1 ATOM 1167 C CG1 . VAL A 1 154 ? 18.293 13.514 49.917 1.00 18.49 ? 150 VAL A CG1 1 ATOM 1168 C CG2 . VAL A 1 154 ? 18.728 12.780 47.651 1.00 18.63 ? 150 VAL A CG2 1 ATOM 1169 N N . CYS A 1 155 ? 18.739 17.373 49.191 1.00 17.59 ? 151 CYS A N 1 ATOM 1170 C CA . CYS A 1 155 ? 19.215 18.460 50.004 1.00 17.66 ? 151 CYS A CA 1 ATOM 1171 C C . CYS A 1 155 ? 19.147 18.140 51.517 1.00 19.14 ? 151 CYS A C 1 ATOM 1172 O O . CYS A 1 155 ? 18.047 17.919 52.058 1.00 19.66 ? 151 CYS A O 1 ATOM 1173 C CB . CYS A 1 155 ? 18.429 19.780 49.754 1.00 19.85 ? 151 CYS A CB 1 ATOM 1174 S SG . CYS A 1 155 ? 18.900 21.147 50.819 1.00 19.80 ? 151 CYS A SG 1 ATOM 1175 N N . ARG A 1 156 ? 20.304 18.071 52.147 1.00 19.06 ? 152 ARG A N 1 ATOM 1176 C CA . ARG A 1 156 ? 20.353 17.681 53.592 1.00 20.11 ? 152 ARG A CA 1 ATOM 1177 C C . ARG A 1 156 ? 20.562 18.844 54.508 1.00 20.58 ? 152 ARG A C 1 ATOM 1178 O O . ARG A 1 156 ? 20.660 18.649 55.741 1.00 21.30 ? 152 ARG A O 1 ATOM 1179 C CB . ARG A 1 156 ? 21.456 16.645 53.812 1.00 21.42 ? 152 ARG A CB 1 ATOM 1180 C CG . ARG A 1 156 ? 21.248 15.402 52.967 1.00 19.45 ? 152 ARG A CG 1 ATOM 1181 C CD . ARG A 1 156 ? 20.095 14.514 53.380 1.00 20.87 ? 152 ARG A CD 1 ATOM 1182 N NE . ARG A 1 156 ? 20.378 13.869 54.687 1.00 22.82 ? 152 ARG A NE 1 ATOM 1183 C CZ . ARG A 1 156 ? 19.513 13.132 55.370 1.00 20.35 ? 152 ARG A CZ 1 ATOM 1184 N NH1 . ARG A 1 156 ? 19.948 12.582 56.544 1.00 23.69 ? 152 ARG A NH1 1 ATOM 1185 N NH2 . ARG A 1 156 ? 18.271 12.884 54.947 1.00 21.02 ? 152 ARG A NH2 1 ATOM 1186 N N . ASP A 1 157 ? 20.611 20.067 53.979 1.00 18.70 ? 153 ASP A N 1 ATOM 1187 C CA . ASP A 1 157 ? 20.818 21.245 54.772 1.00 18.68 ? 153 ASP A CA 1 ATOM 1188 C C . ASP A 1 157 ? 20.208 22.438 54.029 1.00 19.13 ? 153 ASP A C 1 ATOM 1189 O O . ASP A 1 157 ? 20.693 22.776 52.944 1.00 17.89 ? 153 ASP A O 1 ATOM 1190 C CB . ASP A 1 157 ? 22.330 21.473 55.015 1.00 19.44 ? 153 ASP A CB 1 ATOM 1191 C CG . ASP A 1 157 ? 22.612 22.538 56.055 1.00 22.40 ? 153 ASP A CG 1 ATOM 1192 O OD1 . ASP A 1 157 ? 21.929 23.599 56.119 1.00 19.27 ? 153 ASP A OD1 1 ATOM 1193 O OD2 . ASP A 1 157 ? 23.633 22.402 56.823 1.00 24.66 ? 153 ASP A OD2 1 ATOM 1194 N N . PRO A 1 158 ? 19.123 23.035 54.563 1.00 18.39 ? 154 PRO A N 1 ATOM 1195 C CA . PRO A 1 158 ? 18.415 24.045 53.775 1.00 18.29 ? 154 PRO A CA 1 ATOM 1196 C C . PRO A 1 158 ? 19.117 25.357 53.638 1.00 18.23 ? 154 PRO A C 1 ATOM 1197 O O . PRO A 1 158 ? 18.647 26.252 52.945 1.00 17.66 ? 154 PRO A O 1 ATOM 1198 C CB . PRO A 1 158 ? 17.064 24.184 54.507 1.00 18.07 ? 154 PRO A CB 1 ATOM 1199 C CG . PRO A 1 158 ? 17.440 23.947 55.965 1.00 19.12 ? 154 PRO A CG 1 ATOM 1200 C CD . PRO A 1 158 ? 18.485 22.813 55.878 1.00 18.34 ? 154 PRO A CD 1 ATOM 1201 N N . ARG A 1 159 ? 20.307 25.503 54.236 1.00 18.12 ? 155 ARG A N 1 ATOM 1202 C CA . ARG A 1 159 ? 21.084 26.701 54.039 1.00 17.37 ? 155 ARG A CA 1 ATOM 1203 C C . ARG A 1 159 ? 21.676 26.759 52.596 1.00 17.28 ? 155 ARG A C 1 ATOM 1204 O O . ARG A 1 159 ? 22.124 27.808 52.148 1.00 18.51 ? 155 ARG A O 1 ATOM 1205 C CB . ARG A 1 159 ? 22.213 26.732 55.086 1.00 19.03 ? 155 ARG A CB 1 ATOM 1206 C CG . ARG A 1 159 ? 21.599 27.082 56.440 1.00 17.16 ? 155 ARG A CG 1 ATOM 1207 C CD . ARG A 1 159 ? 22.749 27.006 57.523 1.00 19.39 ? 155 ARG A CD 1 ATOM 1208 N NE . ARG A 1 159 ? 23.156 25.632 57.745 1.00 21.42 ? 155 ARG A NE 1 ATOM 1209 C CZ . ARG A 1 159 ? 24.114 25.302 58.631 1.00 23.53 ? 155 ARG A CZ 1 ATOM 1210 N NH1 . ARG A 1 159 ? 24.672 26.267 59.332 1.00 26.61 ? 155 ARG A NH1 1 ATOM 1211 N NH2 . ARG A 1 159 ? 24.484 24.034 58.795 1.00 23.68 ? 155 ARG A NH2 1 ATOM 1212 N N . TRP A 1 160 ? 21.593 25.638 51.903 1.00 16.60 ? 156 TRP A N 1 ATOM 1213 C CA . TRP A 1 160 ? 21.984 25.553 50.465 1.00 17.48 ? 156 TRP A CA 1 ATOM 1214 C C . TRP A 1 160 ? 21.083 26.394 49.541 1.00 17.29 ? 156 TRP A C 1 ATOM 1215 O O . TRP A 1 160 ? 19.835 26.237 49.578 1.00 17.12 ? 156 TRP A O 1 ATOM 1216 C CB . TRP A 1 160 ? 21.929 24.106 50.030 1.00 17.41 ? 156 TRP A CB 1 ATOM 1217 C CG . TRP A 1 160 ? 22.562 23.797 48.663 1.00 17.13 ? 156 TRP A CG 1 ATOM 1218 C CD1 . TRP A 1 160 ? 23.666 24.377 48.131 1.00 17.89 ? 156 TRP A CD1 1 ATOM 1219 C CD2 . TRP A 1 160 ? 22.187 22.735 47.785 1.00 14.88 ? 156 TRP A CD2 1 ATOM 1220 N NE1 . TRP A 1 160 ? 23.986 23.753 46.914 1.00 17.97 ? 156 TRP A NE1 1 ATOM 1221 C CE2 . TRP A 1 160 ? 23.108 22.736 46.695 1.00 16.05 ? 156 TRP A CE2 1 ATOM 1222 C CE3 . TRP A 1 160 ? 21.151 21.788 47.784 1.00 14.83 ? 156 TRP A CE3 1 ATOM 1223 C CZ2 . TRP A 1 160 ? 22.997 21.833 45.614 1.00 16.12 ? 156 TRP A CZ2 1 ATOM 1224 C CZ3 . TRP A 1 160 ? 21.053 20.845 46.746 1.00 16.68 ? 156 TRP A CZ3 1 ATOM 1225 C CH2 . TRP A 1 160 ? 21.976 20.884 45.644 1.00 15.22 ? 156 TRP A CH2 1 ATOM 1226 N N . GLY A 1 161 ? 21.702 27.178 48.672 1.00 16.22 ? 157 GLY A N 1 ATOM 1227 C CA . GLY A 1 161 ? 20.954 28.005 47.694 1.00 16.22 ? 157 GLY A CA 1 ATOM 1228 C C . GLY A 1 161 ? 20.225 27.176 46.663 1.00 16.23 ? 157 GLY A C 1 ATOM 1229 O O . GLY A 1 161 ? 19.436 27.785 45.900 1.00 17.03 ? 157 GLY A O 1 ATOM 1230 N N . ARG A 1 162 ? 20.464 25.866 46.572 1.00 14.84 ? 158 ARG A N 1 ATOM 1231 C CA . ARG A 1 162 ? 19.691 25.040 45.626 1.00 15.19 ? 158 ARG A CA 1 ATOM 1232 C C . ARG A 1 162 ? 18.697 24.085 46.308 1.00 15.27 ? 158 ARG A C 1 ATOM 1233 O O . ARG A 1 162 ? 18.174 23.153 45.675 1.00 15.27 ? 158 ARG A O 1 ATOM 1234 C CB . ARG A 1 162 ? 20.618 24.267 44.649 1.00 15.11 ? 158 ARG A CB 1 ATOM 1235 C CG . ARG A 1 162 ? 21.746 25.151 44.151 1.00 16.35 ? 158 ARG A CG 1 ATOM 1236 C CD . ARG A 1 162 ? 22.538 24.449 43.030 1.00 16.54 ? 158 ARG A CD 1 ATOM 1237 N NE . ARG A 1 162 ? 21.767 24.432 41.786 1.00 16.10 ? 158 ARG A NE 1 ATOM 1238 C CZ . ARG A 1 162 ? 22.296 24.181 40.603 1.00 15.59 ? 158 ARG A CZ 1 ATOM 1239 N NH1 . ARG A 1 162 ? 23.577 23.880 40.478 1.00 15.54 ? 158 ARG A NH1 1 ATOM 1240 N NH2 . ARG A 1 162 ? 21.512 24.172 39.529 1.00 13.58 ? 158 ARG A NH2 1 ATOM 1241 N N . CYS A 1 163 ? 18.383 24.348 47.601 1.00 16.30 ? 159 CYS A N 1 ATOM 1242 C CA . CYS A 1 163 ? 17.495 23.418 48.293 1.00 16.42 ? 159 CYS A CA 1 ATOM 1243 C C . CYS A 1 163 ? 16.140 23.327 47.550 1.00 15.80 ? 159 CYS A C 1 ATOM 1244 O O . CYS A 1 163 ? 15.552 22.269 47.491 1.00 16.04 ? 159 CYS A O 1 ATOM 1245 C CB . CYS A 1 163 ? 17.349 23.860 49.754 1.00 17.95 ? 159 CYS A CB 1 ATOM 1246 S SG . CYS A 1 163 ? 16.988 22.345 50.793 1.00 26.09 ? 159 CYS A SG 1 ATOM 1247 N N . TYR A 1 164 ? 15.703 24.434 46.970 1.00 14.48 ? 160 TYR A N 1 ATOM 1248 C CA . TYR A 1 164 ? 14.405 24.388 46.256 1.00 13.87 ? 160 TYR A CA 1 ATOM 1249 C C . TYR A 1 164 ? 14.425 23.495 44.999 1.00 13.07 ? 160 TYR A C 1 ATOM 1250 O O . TYR A 1 164 ? 13.354 23.069 44.499 1.00 13.33 ? 160 TYR A O 1 ATOM 1251 C CB . TYR A 1 164 ? 13.913 25.771 45.896 1.00 13.56 ? 160 TYR A CB 1 ATOM 1252 C CG . TYR A 1 164 ? 14.705 26.568 44.867 1.00 14.57 ? 160 TYR A CG 1 ATOM 1253 C CD1 . TYR A 1 164 ? 14.502 26.317 43.489 1.00 13.17 ? 160 TYR A CD1 1 ATOM 1254 C CD2 . TYR A 1 164 ? 15.623 27.536 45.248 1.00 14.73 ? 160 TYR A CD2 1 ATOM 1255 C CE1 . TYR A 1 164 ? 15.176 27.026 42.512 1.00 11.98 ? 160 TYR A CE1 1 ATOM 1256 C CE2 . TYR A 1 164 ? 16.302 28.310 44.277 1.00 14.61 ? 160 TYR A CE2 1 ATOM 1257 C CZ . TYR A 1 164 ? 16.108 28.008 42.929 1.00 15.38 ? 160 TYR A CZ 1 ATOM 1258 O OH . TYR A 1 164 ? 16.750 28.791 41.975 1.00 15.61 ? 160 TYR A OH 1 ATOM 1259 N N . GLU A 1 165 ? 15.634 23.212 44.485 1.00 14.03 ? 161 GLU A N 1 ATOM 1260 C CA . GLU A 1 165 ? 15.731 22.300 43.353 1.00 13.91 ? 161 GLU A CA 1 ATOM 1261 C C . GLU A 1 165 ? 15.758 20.822 43.731 1.00 14.53 ? 161 GLU A C 1 ATOM 1262 O O . GLU A 1 165 ? 15.773 19.941 42.847 1.00 15.09 ? 161 GLU A O 1 ATOM 1263 C CB . GLU A 1 165 ? 17.015 22.615 42.536 1.00 12.68 ? 161 GLU A CB 1 ATOM 1264 C CG . GLU A 1 165 ? 17.047 24.075 42.009 1.00 13.39 ? 161 GLU A CG 1 ATOM 1265 C CD . GLU A 1 165 ? 18.074 24.217 40.885 1.00 15.33 ? 161 GLU A CD 1 ATOM 1266 O OE1 . GLU A 1 165 ? 19.031 24.973 41.070 1.00 16.03 ? 161 GLU A OE1 1 ATOM 1267 O OE2 . GLU A 1 165 ? 17.870 23.609 39.844 1.00 16.53 ? 161 GLU A OE2 1 ATOM 1268 N N . SER A 1 166 ? 15.688 20.556 45.062 1.00 15.53 ? 162 SER A N 1 ATOM 1269 C CA . SER A 1 166 ? 15.643 19.182 45.568 1.00 15.00 ? 162 SER A CA 1 ATOM 1270 C C . SER A 1 166 ? 14.204 18.844 45.948 1.00 15.77 ? 162 SER A C 1 ATOM 1271 O O . SER A 1 166 ? 13.564 19.646 46.644 1.00 15.78 ? 162 SER A O 1 ATOM 1272 C CB . SER A 1 166 ? 16.567 19.085 46.808 1.00 15.79 ? 162 SER A CB 1 ATOM 1273 O OG . SER A 1 166 ? 16.387 17.779 47.385 1.00 17.25 ? 162 SER A OG 1 ATOM 1274 N N . TYR A 1 167 ? 13.718 17.678 45.524 1.00 16.01 ? 163 TYR A N 1 ATOM 1275 C CA . TYR A 1 167 ? 12.335 17.295 45.883 1.00 15.37 ? 163 TYR A CA 1 ATOM 1276 C C . TYR A 1 167 ? 12.211 17.079 47.395 1.00 16.41 ? 163 TYR A C 1 ATOM 1277 O O . TYR A 1 167 ? 11.091 17.273 47.928 1.00 15.39 ? 163 TYR A O 1 ATOM 1278 C CB . TYR A 1 167 ? 11.869 16.029 45.192 1.00 15.10 ? 163 TYR A CB 1 ATOM 1279 C CG . TYR A 1 167 ? 11.880 16.110 43.682 1.00 14.86 ? 163 TYR A CG 1 ATOM 1280 C CD1 . TYR A 1 167 ? 10.872 16.797 42.966 1.00 14.33 ? 163 TYR A CD1 1 ATOM 1281 C CD2 . TYR A 1 167 ? 12.871 15.441 42.952 1.00 15.03 ? 163 TYR A CD2 1 ATOM 1282 C CE1 . TYR A 1 167 ? 10.877 16.810 41.565 1.00 13.65 ? 163 TYR A CE1 1 ATOM 1283 C CE2 . TYR A 1 167 ? 12.885 15.451 41.548 1.00 15.98 ? 163 TYR A CE2 1 ATOM 1284 C CZ . TYR A 1 167 ? 11.904 16.160 40.848 1.00 14.79 ? 163 TYR A CZ 1 ATOM 1285 O OH . TYR A 1 167 ? 11.860 16.206 39.467 1.00 16.97 ? 163 TYR A OH 1 ATOM 1286 N N . SER A 1 168 ? 13.267 16.671 48.078 1.00 16.46 ? 164 SER A N 1 ATOM 1287 C CA . SER A 1 168 ? 13.131 16.258 49.471 1.00 17.59 ? 164 SER A CA 1 ATOM 1288 C C . SER A 1 168 ? 14.483 16.034 50.100 1.00 17.98 ? 164 SER A C 1 ATOM 1289 O O . SER A 1 168 ? 15.489 15.747 49.398 1.00 18.36 ? 164 SER A O 1 ATOM 1290 C CB . SER A 1 168 ? 12.292 14.978 49.541 1.00 18.64 ? 164 SER A CB 1 ATOM 1291 O OG . SER A 1 168 ? 12.068 14.592 50.923 1.00 18.55 ? 164 SER A OG 1 ATOM 1292 N N . GLU A 1 169 ? 14.509 16.108 51.432 1.00 18.31 ? 165 GLU A N 1 ATOM 1293 C CA . GLU A 1 169 ? 15.667 15.604 52.205 1.00 18.67 ? 165 GLU A CA 1 ATOM 1294 C C . GLU A 1 169 ? 15.633 14.045 52.304 1.00 18.93 ? 165 GLU A C 1 ATOM 1295 O O . GLU A 1 169 ? 16.658 13.435 52.694 1.00 20.64 ? 165 GLU A O 1 ATOM 1296 C CB . GLU A 1 169 ? 15.695 16.243 53.614 1.00 18.80 ? 165 GLU A CB 1 ATOM 1297 C CG . GLU A 1 169 ? 14.653 15.625 54.552 1.00 19.48 ? 165 GLU A CG 1 ATOM 1298 C CD . GLU A 1 169 ? 14.432 16.458 55.812 1.00 25.03 ? 165 GLU A CD 1 ATOM 1299 O OE1 . GLU A 1 169 ? 14.667 17.681 55.813 1.00 24.99 ? 165 GLU A OE1 1 ATOM 1300 O OE2 . GLU A 1 169 ? 14.005 15.846 56.804 1.00 28.63 ? 165 GLU A OE2 1 ATOM 1301 N N . ASP A 1 170 ? 14.518 13.438 51.957 1.00 19.36 ? 166 ASP A N 1 ATOM 1302 C CA . ASP A 1 170 ? 14.307 11.994 52.038 1.00 20.31 ? 166 ASP A CA 1 ATOM 1303 C C . ASP A 1 170 ? 14.510 11.422 50.650 1.00 19.97 ? 166 ASP A C 1 ATOM 1304 O O . ASP A 1 170 ? 13.721 11.646 49.702 1.00 19.24 ? 166 ASP A O 1 ATOM 1305 C CB . ASP A 1 170 ? 12.902 11.718 52.568 1.00 21.81 ? 166 ASP A CB 1 ATOM 1306 C CG . ASP A 1 170 ? 12.604 10.237 52.745 1.00 25.04 ? 166 ASP A CG 1 ATOM 1307 O OD1 . ASP A 1 170 ? 13.357 9.380 52.228 1.00 26.35 ? 166 ASP A OD1 1 ATOM 1308 O OD2 . ASP A 1 170 ? 11.533 9.949 53.357 1.00 29.28 ? 166 ASP A OD2 1 ATOM 1309 N N . ARG A 1 171 ? 15.606 10.673 50.501 1.00 20.63 ? 167 ARG A N 1 ATOM 1310 C CA . ARG A 1 171 ? 15.873 10.004 49.232 1.00 20.03 ? 167 ARG A CA 1 ATOM 1311 C C . ARG A 1 171 ? 14.745 9.191 48.627 1.00 20.33 ? 167 ARG A C 1 ATOM 1312 O O . ARG A 1 171 ? 14.622 9.087 47.413 1.00 19.57 ? 167 ARG A O 1 ATOM 1313 C CB . ARG A 1 171 ? 17.202 9.222 49.358 1.00 20.90 ? 167 ARG A CB 1 ATOM 1314 C CG . ARG A 1 171 ? 17.149 8.031 50.358 1.00 22.34 ? 167 ARG A CG 1 ATOM 1315 C CD . ARG A 1 171 ? 16.658 6.745 49.724 1.00 23.14 ? 167 ARG A CD 1 ATOM 1316 N NE . ARG A 1 171 ? 16.505 5.701 50.777 1.00 29.34 ? 167 ARG A NE 1 ATOM 1317 C CZ . ARG A 1 171 ? 16.024 4.478 50.574 1.00 32.79 ? 167 ARG A CZ 1 ATOM 1318 N NH1 . ARG A 1 171 ? 15.930 3.630 51.620 1.00 37.04 ? 167 ARG A NH1 1 ATOM 1319 N NH2 . ARG A 1 171 ? 15.648 4.078 49.371 1.00 32.56 ? 167 ARG A NH2 1 ATOM 1320 N N . ARG A 1 172 ? 13.867 8.586 49.461 1.00 19.57 ? 168 ARG A N 1 ATOM 1321 C CA . ARG A 1 172 ? 12.730 7.875 48.944 1.00 20.51 ? 168 ARG A CA 1 ATOM 1322 C C . ARG A 1 172 ? 11.775 8.749 48.129 1.00 19.09 ? 168 ARG A C 1 ATOM 1323 O O . ARG A 1 172 ? 11.248 8.291 47.127 1.00 19.75 ? 168 ARG A O 1 ATOM 1324 C CB . ARG A 1 172 ? 11.946 7.177 50.096 1.00 21.75 ? 168 ARG A CB 1 ATOM 1325 C CG . ARG A 1 172 ? 12.788 6.027 50.750 1.00 26.04 ? 168 ARG A CG 1 ATOM 1326 C CD . ARG A 1 172 ? 12.134 5.509 52.054 1.00 33.62 ? 168 ARG A CD 1 ATOM 1327 N NE . ARG A 1 172 ? 12.204 6.519 53.117 1.00 42.56 ? 168 ARG A NE 1 ATOM 1328 C CZ . ARG A 1 172 ? 11.471 6.528 54.243 1.00 47.09 ? 168 ARG A CZ 1 ATOM 1329 N NH1 . ARG A 1 172 ? 10.587 5.563 54.503 1.00 49.20 ? 168 ARG A NH1 1 ATOM 1330 N NH2 . ARG A 1 172 ? 11.625 7.514 55.126 1.00 46.80 ? 168 ARG A NH2 1 ATOM 1331 N N . ILE A 1 173 ? 11.585 9.993 48.570 1.00 19.52 ? 169 ILE A N 1 ATOM 1332 C CA . ILE A 1 173 ? 10.711 10.923 47.850 1.00 19.08 ? 169 ILE A CA 1 ATOM 1333 C C . ILE A 1 173 ? 11.413 11.319 46.528 1.00 17.61 ? 169 ILE A C 1 ATOM 1334 O O . ILE A 1 173 ? 10.809 11.293 45.478 1.00 18.02 ? 169 ILE A O 1 ATOM 1335 C CB . ILE A 1 173 ? 10.340 12.145 48.713 1.00 19.36 ? 169 ILE A CB 1 ATOM 1336 C CG1 . ILE A 1 173 ? 9.446 11.674 49.887 1.00 20.81 ? 169 ILE A CG1 1 ATOM 1337 C CG2 . ILE A 1 173 ? 9.528 13.151 47.873 1.00 21.05 ? 169 ILE A CG2 1 ATOM 1338 C CD1 . ILE A 1 173 ? 9.237 12.760 50.915 1.00 21.16 ? 169 ILE A CD1 1 ATOM 1339 N N . VAL A 1 174 ? 12.692 11.604 46.618 1.00 17.98 ? 170 VAL A N 1 ATOM 1340 C CA . VAL A 1 174 ? 13.471 11.955 45.378 1.00 17.67 ? 170 VAL A CA 1 ATOM 1341 C C . VAL A 1 174 ? 13.402 10.795 44.374 1.00 17.74 ? 170 VAL A C 1 ATOM 1342 O O . VAL A 1 174 ? 13.160 10.990 43.187 1.00 18.29 ? 170 VAL A O 1 ATOM 1343 C CB . VAL A 1 174 ? 14.900 12.297 45.718 1.00 16.24 ? 170 VAL A CB 1 ATOM 1344 C CG1 . VAL A 1 174 ? 15.751 12.554 44.405 1.00 17.39 ? 170 VAL A CG1 1 ATOM 1345 C CG2 . VAL A 1 174 ? 15.009 13.537 46.630 1.00 15.34 ? 170 VAL A CG2 1 ATOM 1346 N N . GLN A 1 175 ? 13.565 9.540 44.851 1.00 17.75 ? 171 GLN A N 1 ATOM 1347 C CA . GLN A 1 175 ? 13.472 8.405 43.960 1.00 17.59 ? 171 GLN A CA 1 ATOM 1348 C C . GLN A 1 175 ? 12.108 8.354 43.312 1.00 17.45 ? 171 GLN A C 1 ATOM 1349 O O . GLN A 1 175 ? 11.992 8.079 42.135 1.00 18.33 ? 171 GLN A O 1 ATOM 1350 C CB . GLN A 1 175 ? 13.690 7.072 44.743 1.00 17.84 ? 171 GLN A CB 1 ATOM 1351 C CG . GLN A 1 175 ? 15.110 6.872 45.160 1.00 19.68 ? 171 GLN A CG 1 ATOM 1352 C CD . GLN A 1 175 ? 15.264 5.527 45.909 1.00 25.09 ? 171 GLN A CD 1 ATOM 1353 O OE1 . GLN A 1 175 ? 15.624 4.478 45.340 1.00 26.41 ? 171 GLN A OE1 1 ATOM 1354 N NE2 . GLN A 1 175 ? 14.958 5.568 47.159 1.00 19.33 ? 171 GLN A NE2 1 ATOM 1355 N N . SER A 1 176 ? 11.050 8.621 44.093 1.00 17.09 ? 172 SER A N 1 ATOM 1356 C CA . SER A 1 176 ? 9.711 8.543 43.501 1.00 17.96 ? 172 SER A CA 1 ATOM 1357 C C . SER A 1 176 ? 9.509 9.567 42.364 1.00 16.92 ? 172 SER A C 1 ATOM 1358 O O . SER A 1 176 ? 8.789 9.322 41.409 1.00 19.30 ? 172 SER A O 1 ATOM 1359 C CB . SER A 1 176 ? 8.597 8.706 44.565 1.00 19.98 ? 172 SER A CB 1 ATOM 1360 O OG . SER A 1 176 ? 8.518 10.019 45.090 1.00 23.73 ? 172 SER A OG 1 ATOM 1361 N N . MET A 1 177 ? 10.154 10.708 42.516 1.00 18.45 ? 173 MET A N 1 ATOM 1362 C CA . MET A 1 177 ? 9.914 11.807 41.568 1.00 18.05 ? 173 MET A CA 1 ATOM 1363 C C . MET A 1 177 ? 10.816 11.692 40.349 1.00 18.89 ? 173 MET A C 1 ATOM 1364 O O . MET A 1 177 ? 10.694 12.503 39.409 1.00 18.15 ? 173 MET A O 1 ATOM 1365 C CB . MET A 1 177 ? 10.150 13.150 42.279 1.00 17.88 ? 173 MET A CB 1 ATOM 1366 C CG A MET A 1 177 ? 9.194 13.405 43.445 0.60 19.01 ? 173 MET A CG 1 ATOM 1367 C CG B MET A 1 177 ? 9.471 13.241 43.644 0.40 21.00 ? 173 MET A CG 1 ATOM 1368 S SD A MET A 1 177 ? 7.528 13.239 42.917 0.60 19.40 ? 173 MET A SD 1 ATOM 1369 S SD B MET A 1 177 ? 8.072 14.349 43.744 0.40 22.22 ? 173 MET A SD 1 ATOM 1370 C CE A MET A 1 177 ? 6.509 13.615 44.346 0.60 17.01 ? 173 MET A CE 1 ATOM 1371 C CE B MET A 1 177 ? 7.141 13.652 45.112 0.40 19.70 ? 173 MET A CE 1 ATOM 1372 N N . THR A 1 178 ? 11.629 10.641 40.271 1.00 18.42 ? 174 THR A N 1 ATOM 1373 C CA . THR A 1 178 ? 12.353 10.379 39.000 1.00 18.60 ? 174 THR A CA 1 ATOM 1374 C C . THR A 1 178 ? 11.398 10.021 37.860 1.00 17.21 ? 174 THR A C 1 ATOM 1375 O O . THR A 1 178 ? 11.814 9.876 36.712 1.00 17.61 ? 174 THR A O 1 ATOM 1376 C CB . THR A 1 178 ? 13.431 9.280 39.155 1.00 19.06 ? 174 THR A CB 1 ATOM 1377 O OG1 . THR A 1 178 ? 12.752 8.054 39.533 1.00 18.98 ? 174 THR A OG1 1 ATOM 1378 C CG2 . THR A 1 178 ? 14.533 9.682 40.148 1.00 19.30 ? 174 THR A CG2 1 ATOM 1379 N N . GLU A 1 179 ? 10.081 9.906 38.126 1.00 16.35 ? 175 GLU A N 1 ATOM 1380 C CA . GLU A 1 179 ? 9.057 9.858 37.107 1.00 15.79 ? 175 GLU A CA 1 ATOM 1381 C C . GLU A 1 179 ? 9.075 11.060 36.137 1.00 15.01 ? 175 GLU A C 1 ATOM 1382 O O . GLU A 1 179 ? 8.485 10.991 35.065 1.00 16.49 ? 175 GLU A O 1 ATOM 1383 C CB . GLU A 1 179 ? 7.644 9.746 37.761 1.00 17.18 ? 175 GLU A CB 1 ATOM 1384 C CG . GLU A 1 179 ? 7.364 8.329 38.301 1.00 20.27 ? 175 GLU A CG 1 ATOM 1385 C CD . GLU A 1 179 ? 7.339 7.316 37.169 1.00 20.20 ? 175 GLU A CD 1 ATOM 1386 O OE1 . GLU A 1 179 ? 8.390 6.659 36.993 1.00 23.72 ? 175 GLU A OE1 1 ATOM 1387 O OE2 . GLU A 1 179 ? 6.326 7.192 36.429 1.00 23.67 ? 175 GLU A OE2 1 ATOM 1388 N N . LEU A 1 180 ? 9.716 12.157 36.571 1.00 15.33 ? 176 LEU A N 1 ATOM 1389 C CA . LEU A 1 180 ? 9.924 13.279 35.619 1.00 15.36 ? 176 LEU A CA 1 ATOM 1390 C C . LEU A 1 180 ? 10.574 12.760 34.347 1.00 14.48 ? 176 LEU A C 1 ATOM 1391 O O . LEU A 1 180 ? 10.235 13.212 33.236 1.00 14.56 ? 176 LEU A O 1 ATOM 1392 C CB . LEU A 1 180 ? 10.791 14.395 36.219 1.00 13.33 ? 176 LEU A CB 1 ATOM 1393 C CG . LEU A 1 180 ? 10.774 15.668 35.323 1.00 14.62 ? 176 LEU A CG 1 ATOM 1394 C CD1 . LEU A 1 180 ? 9.505 16.564 35.585 1.00 14.61 ? 176 LEU A CD1 1 ATOM 1395 C CD2 . LEU A 1 180 ? 12.018 16.445 35.641 1.00 14.59 ? 176 LEU A CD2 1 ATOM 1396 N N . ILE A 1 181 ? 11.514 11.813 34.516 1.00 14.67 ? 177 ILE A N 1 ATOM 1397 C CA . ILE A 1 181 ? 12.334 11.372 33.390 1.00 15.81 ? 177 ILE A CA 1 ATOM 1398 C C . ILE A 1 181 ? 11.519 10.738 32.245 1.00 15.53 ? 177 ILE A C 1 ATOM 1399 O O . ILE A 1 181 ? 11.606 11.197 31.109 1.00 15.97 ? 177 ILE A O 1 ATOM 1400 C CB . ILE A 1 181 ? 13.505 10.500 33.867 1.00 14.57 ? 177 ILE A CB 1 ATOM 1401 C CG1 . ILE A 1 181 ? 14.495 11.345 34.679 1.00 14.51 ? 177 ILE A CG1 1 ATOM 1402 C CG2 . ILE A 1 181 ? 14.140 9.817 32.637 1.00 16.35 ? 177 ILE A CG2 1 ATOM 1403 C CD1 . ILE A 1 181 ? 15.411 10.488 35.548 1.00 16.60 ? 177 ILE A CD1 1 ATOM 1404 N N . PRO A 1 182 ? 10.680 9.693 32.487 1.00 15.88 ? 178 PRO A N 1 ATOM 1405 C CA . PRO A 1 182 ? 9.827 9.181 31.394 1.00 16.62 ? 178 PRO A CA 1 ATOM 1406 C C . PRO A 1 182 ? 8.750 10.142 30.924 1.00 15.13 ? 178 PRO A C 1 ATOM 1407 O O . PRO A 1 182 ? 8.248 10.032 29.808 1.00 16.99 ? 178 PRO A O 1 ATOM 1408 C CB . PRO A 1 182 ? 9.194 7.916 31.997 1.00 17.14 ? 178 PRO A CB 1 ATOM 1409 C CG . PRO A 1 182 ? 9.321 8.090 33.454 1.00 16.25 ? 178 PRO A CG 1 ATOM 1410 C CD . PRO A 1 182 ? 10.586 8.876 33.713 1.00 16.91 ? 178 PRO A CD 1 ATOM 1411 N N . GLY A 1 183 ? 8.407 11.141 31.784 1.00 14.93 ? 179 GLY A N 1 ATOM 1412 C CA . GLY A 1 183 ? 7.584 12.250 31.255 1.00 14.70 ? 179 GLY A CA 1 ATOM 1413 C C . GLY A 1 183 ? 8.304 13.071 30.188 1.00 14.39 ? 179 GLY A C 1 ATOM 1414 O O . GLY A 1 183 ? 7.760 13.267 29.110 1.00 15.69 ? 179 GLY A O 1 ATOM 1415 N N . LEU A 1 184 ? 9.538 13.479 30.477 1.00 14.05 ? 180 LEU A N 1 ATOM 1416 C CA . LEU A 1 184 ? 10.313 14.273 29.508 1.00 13.88 ? 180 LEU A CA 1 ATOM 1417 C C . LEU A 1 184 ? 10.701 13.456 28.266 1.00 13.58 ? 180 LEU A C 1 ATOM 1418 O O . LEU A 1 184 ? 10.661 13.979 27.158 1.00 14.00 ? 180 LEU A O 1 ATOM 1419 C CB . LEU A 1 184 ? 11.616 14.715 30.142 1.00 13.45 ? 180 LEU A CB 1 ATOM 1420 C CG . LEU A 1 184 ? 11.461 15.820 31.177 1.00 12.79 ? 180 LEU A CG 1 ATOM 1421 C CD1 . LEU A 1 184 ? 12.783 15.911 32.023 1.00 13.93 ? 180 LEU A CD1 1 ATOM 1422 C CD2 . LEU A 1 184 ? 11.132 17.211 30.554 1.00 14.33 ? 180 LEU A CD2 1 ATOM 1423 N N . GLN A 1 185 ? 11.085 12.183 28.488 1.00 14.23 ? 181 GLN A N 1 ATOM 1424 C CA . GLN A 1 185 ? 11.708 11.386 27.405 1.00 14.06 ? 181 GLN A CA 1 ATOM 1425 C C . GLN A 1 185 ? 10.776 10.375 26.775 1.00 16.20 ? 181 GLN A C 1 ATOM 1426 O O . GLN A 1 185 ? 11.026 9.906 25.659 1.00 16.56 ? 181 GLN A O 1 ATOM 1427 C CB . GLN A 1 185 ? 12.884 10.597 27.955 1.00 14.35 ? 181 GLN A CB 1 ATOM 1428 C CG . GLN A 1 185 ? 13.998 11.368 28.575 1.00 14.91 ? 181 GLN A CG 1 ATOM 1429 C CD . GLN A 1 185 ? 15.203 10.488 28.882 1.00 19.09 ? 181 GLN A CD 1 ATOM 1430 O OE1 . GLN A 1 185 ? 15.072 9.299 29.368 1.00 18.49 ? 181 GLN A OE1 1 ATOM 1431 N NE2 . GLN A 1 185 ? 16.378 11.024 28.640 1.00 12.59 ? 181 GLN A NE2 1 ATOM 1432 N N . GLY A 1 186 ? 9.662 10.076 27.449 1.00 16.84 ? 182 GLY A N 1 ATOM 1433 C CA . GLY A 1 186 ? 8.820 8.924 26.984 1.00 17.37 ? 182 GLY A CA 1 ATOM 1434 C C . GLY A 1 186 ? 9.118 7.689 27.809 1.00 17.95 ? 182 GLY A C 1 ATOM 1435 O O . GLY A 1 186 ? 10.208 7.511 28.348 1.00 17.84 ? 182 GLY A O 1 ATOM 1436 N N . ASP A 1 187 ? 8.096 6.821 27.975 1.00 19.25 ? 183 ASP A N 1 ATOM 1437 C CA . ASP A 1 187 ? 8.308 5.547 28.689 1.00 20.60 ? 183 ASP A CA 1 ATOM 1438 C C . ASP A 1 187 ? 9.203 4.602 27.891 1.00 20.97 ? 183 ASP A C 1 ATOM 1439 O O . ASP A 1 187 ? 9.037 4.497 26.679 1.00 21.70 ? 183 ASP A O 1 ATOM 1440 C CB . ASP A 1 187 ? 6.952 4.856 28.843 1.00 22.67 ? 183 ASP A CB 1 ATOM 1441 C CG . ASP A 1 187 ? 6.050 5.545 29.869 1.00 23.21 ? 183 ASP A CG 1 ATOM 1442 O OD1 . ASP A 1 187 ? 6.523 5.907 30.950 1.00 25.98 ? 183 ASP A OD1 1 ATOM 1443 O OD2 . ASP A 1 187 ? 4.834 5.593 29.590 1.00 32.74 ? 183 ASP A OD2 1 ATOM 1444 N N . VAL A 1 188 ? 10.085 3.907 28.597 1.00 22.69 ? 184 VAL A N 1 ATOM 1445 C CA . VAL A 1 188 ? 10.998 2.912 27.981 1.00 24.76 ? 184 VAL A CA 1 ATOM 1446 C C . VAL A 1 188 ? 10.205 1.648 27.609 1.00 28.03 ? 184 VAL A C 1 ATOM 1447 O O . VAL A 1 188 ? 9.173 1.382 28.224 1.00 28.81 ? 184 VAL A O 1 ATOM 1448 C CB . VAL A 1 188 ? 12.208 2.587 28.890 1.00 24.20 ? 184 VAL A CB 1 ATOM 1449 C CG1 . VAL A 1 188 ? 12.985 3.896 29.237 1.00 23.31 ? 184 VAL A CG1 1 ATOM 1450 C CG2 . VAL A 1 188 ? 11.797 1.889 30.237 1.00 23.37 ? 184 VAL A CG2 1 ATOM 1451 N N . PRO A 1 189 ? 10.663 0.911 26.579 1.00 30.09 ? 185 PRO A N 1 ATOM 1452 C CA . PRO A 1 189 ? 9.886 -0.287 26.195 1.00 33.15 ? 185 PRO A CA 1 ATOM 1453 C C . PRO A 1 189 ? 9.966 -1.398 27.222 1.00 35.19 ? 185 PRO A C 1 ATOM 1454 O O . PRO A 1 189 ? 10.712 -1.300 28.204 1.00 34.42 ? 185 PRO A O 1 ATOM 1455 C CB . PRO A 1 189 ? 10.500 -0.713 24.855 1.00 33.56 ? 185 PRO A CB 1 ATOM 1456 C CG . PRO A 1 189 ? 11.811 -0.037 24.753 1.00 31.81 ? 185 PRO A CG 1 ATOM 1457 C CD . PRO A 1 189 ? 11.763 1.205 25.648 1.00 29.77 ? 185 PRO A CD 1 ATOM 1458 N N . LYS A 1 190 ? 9.184 -2.456 26.998 1.00 38.73 ? 186 LYS A N 1 ATOM 1459 C CA . LYS A 1 190 ? 9.128 -3.618 27.905 1.00 41.46 ? 186 LYS A CA 1 ATOM 1460 C C . LYS A 1 190 ? 10.530 -4.200 28.133 1.00 41.60 ? 186 LYS A C 1 ATOM 1461 O O . LYS A 1 190 ? 10.937 -4.463 29.265 1.00 42.27 ? 186 LYS A O 1 ATOM 1462 C CB . LYS A 1 190 ? 8.229 -4.701 27.277 1.00 42.37 ? 186 LYS A CB 1 ATOM 1463 C CG . LYS A 1 190 ? 7.180 -5.312 28.202 1.00 46.74 ? 186 LYS A CG 1 ATOM 1464 C CD . LYS A 1 190 ? 7.750 -6.051 29.425 1.00 51.65 ? 186 LYS A CD 1 ATOM 1465 C CE . LYS A 1 190 ? 6.600 -6.685 30.231 1.00 54.24 ? 186 LYS A CE 1 ATOM 1466 N NZ . LYS A 1 190 ? 7.044 -7.226 31.550 1.00 56.80 ? 186 LYS A NZ 1 ATOM 1467 N N . ASP A 1 191 ? 11.271 -4.347 27.041 1.00 42.34 ? 187 ASP A N 1 ATOM 1468 C CA . ASP A 1 191 ? 12.567 -5.051 27.031 1.00 43.89 ? 187 ASP A CA 1 ATOM 1469 C C . ASP A 1 191 ? 13.696 -4.370 27.836 1.00 41.86 ? 187 ASP A C 1 ATOM 1470 O O . ASP A 1 191 ? 14.752 -4.952 28.061 1.00 42.95 ? 187 ASP A O 1 ATOM 1471 C CB . ASP A 1 191 ? 13.026 -5.253 25.563 1.00 45.23 ? 187 ASP A CB 1 ATOM 1472 C CG . ASP A 1 191 ? 12.854 -3.968 24.688 1.00 49.89 ? 187 ASP A CG 1 ATOM 1473 O OD1 . ASP A 1 191 ? 13.661 -2.991 24.835 1.00 53.61 ? 187 ASP A OD1 1 ATOM 1474 O OD2 . ASP A 1 191 ? 11.917 -3.955 23.838 1.00 52.96 ? 187 ASP A OD2 1 ATOM 1475 N N . PHE A 1 192 ? 13.454 -3.152 28.303 1.00 38.90 ? 188 PHE A N 1 ATOM 1476 C CA . PHE A 1 192 ? 14.541 -2.201 28.508 1.00 34.58 ? 188 PHE A CA 1 ATOM 1477 C C . PHE A 1 192 ? 15.707 -2.552 29.442 1.00 32.46 ? 188 PHE A C 1 ATOM 1478 O O . PHE A 1 192 ? 15.515 -2.850 30.622 1.00 33.33 ? 188 PHE A O 1 ATOM 1479 C CB . PHE A 1 192 ? 13.957 -0.864 28.941 1.00 34.06 ? 188 PHE A CB 1 ATOM 1480 C CG . PHE A 1 192 ? 14.888 0.276 28.696 1.00 30.72 ? 188 PHE A CG 1 ATOM 1481 C CD1 . PHE A 1 192 ? 15.099 0.704 27.391 1.00 31.67 ? 188 PHE A CD1 1 ATOM 1482 C CD2 . PHE A 1 192 ? 15.561 0.888 29.746 1.00 27.97 ? 188 PHE A CD2 1 ATOM 1483 C CE1 . PHE A 1 192 ? 15.941 1.763 27.125 1.00 29.28 ? 188 PHE A CE1 1 ATOM 1484 C CE2 . PHE A 1 192 ? 16.466 1.931 29.491 1.00 25.30 ? 188 PHE A CE2 1 ATOM 1485 C CZ . PHE A 1 192 ? 16.626 2.368 28.174 1.00 26.99 ? 188 PHE A CZ 1 ATOM 1486 N N . THR A 1 193 ? 16.927 -2.405 28.932 1.00 29.48 ? 189 THR A N 1 ATOM 1487 C CA . THR A 1 193 ? 18.109 -2.582 29.748 1.00 27.55 ? 189 THR A CA 1 ATOM 1488 C C . THR A 1 193 ? 18.506 -1.341 30.560 1.00 26.05 ? 189 THR A C 1 ATOM 1489 O O . THR A 1 193 ? 18.859 -0.305 29.958 1.00 24.77 ? 189 THR A O 1 ATOM 1490 C CB . THR A 1 193 ? 19.304 -2.982 28.889 1.00 28.31 ? 189 THR A CB 1 ATOM 1491 O OG1 . THR A 1 193 ? 18.961 -4.178 28.187 1.00 31.66 ? 189 THR A OG1 1 ATOM 1492 C CG2 . THR A 1 193 ? 20.520 -3.232 29.763 1.00 29.39 ? 189 THR A CG2 1 ATOM 1493 N N . SER A 1 194 ? 18.504 -1.468 31.890 1.00 24.17 ? 190 SER A N 1 ATOM 1494 C CA . SER A 1 194 ? 18.793 -0.336 32.784 1.00 23.43 ? 190 SER A CA 1 ATOM 1495 C C . SER A 1 194 ? 20.151 0.277 32.419 1.00 24.00 ? 190 SER A C 1 ATOM 1496 O O . SER A 1 194 ? 21.151 -0.439 32.209 1.00 23.67 ? 190 SER A O 1 ATOM 1497 C CB . SER A 1 194 ? 18.743 -0.759 34.253 1.00 23.17 ? 190 SER A CB 1 ATOM 1498 O OG . SER A 1 194 ? 19.242 0.238 35.131 1.00 23.57 ? 190 SER A OG 1 ATOM 1499 N N . GLY A 1 195 ? 20.190 1.625 32.336 1.00 21.19 ? 191 GLY A N 1 ATOM 1500 C CA . GLY A 1 195 ? 21.434 2.291 31.978 1.00 20.90 ? 191 GLY A CA 1 ATOM 1501 C C . GLY A 1 195 ? 21.514 2.696 30.512 1.00 19.60 ? 191 GLY A C 1 ATOM 1502 O O . GLY A 1 195 ? 22.319 3.591 30.186 1.00 19.81 ? 191 GLY A O 1 ATOM 1503 N N . MET A 1 196 ? 20.715 2.074 29.641 1.00 19.68 ? 192 MET A N 1 ATOM 1504 C CA . MET A 1 196 ? 20.687 2.512 28.237 1.00 20.13 ? 192 MET A CA 1 ATOM 1505 C C . MET A 1 196 ? 19.987 3.886 28.163 1.00 20.19 ? 192 MET A C 1 ATOM 1506 O O . MET A 1 196 ? 19.068 4.168 28.961 1.00 21.42 ? 192 MET A O 1 ATOM 1507 C CB . MET A 1 196 ? 19.976 1.500 27.344 1.00 20.82 ? 192 MET A CB 1 ATOM 1508 C CG . MET A 1 196 ? 20.817 0.221 27.104 1.00 21.84 ? 192 MET A CG 1 ATOM 1509 S SD . MET A 1 196 ? 22.312 0.589 26.092 1.00 26.42 ? 192 MET A SD 1 ATOM 1510 C CE . MET A 1 196 ? 21.548 0.918 24.527 1.00 24.38 ? 192 MET A CE 1 ATOM 1511 N N . PRO A 1 197 ? 20.394 4.760 27.249 1.00 18.19 ? 193 PRO A N 1 ATOM 1512 C CA . PRO A 1 197 ? 19.637 6.024 27.071 1.00 17.37 ? 193 PRO A CA 1 ATOM 1513 C C . PRO A 1 197 ? 18.352 5.806 26.273 1.00 17.90 ? 193 PRO A C 1 ATOM 1514 O O . PRO A 1 197 ? 18.254 4.899 25.402 1.00 18.89 ? 193 PRO A O 1 ATOM 1515 C CB . PRO A 1 197 ? 20.626 6.912 26.284 1.00 17.12 ? 193 PRO A CB 1 ATOM 1516 C CG . PRO A 1 197 ? 21.341 5.836 25.386 1.00 16.25 ? 193 PRO A CG 1 ATOM 1517 C CD . PRO A 1 197 ? 21.500 4.622 26.266 1.00 17.95 ? 193 PRO A CD 1 ATOM 1518 N N . PHE A 1 198 ? 17.343 6.662 26.478 1.00 17.09 ? 194 PHE A N 1 ATOM 1519 C CA . PHE A 1 198 ? 16.146 6.560 25.703 1.00 17.75 ? 194 PHE A CA 1 ATOM 1520 C C . PHE A 1 198 ? 15.480 7.933 25.495 1.00 16.82 ? 194 PHE A C 1 ATOM 1521 O O . PHE A 1 198 ? 15.392 8.696 26.447 1.00 17.93 ? 194 PHE A O 1 ATOM 1522 C CB . PHE A 1 198 ? 15.109 5.650 26.466 1.00 18.56 ? 194 PHE A CB 1 ATOM 1523 C CG . PHE A 1 198 ? 13.826 5.512 25.736 1.00 19.79 ? 194 PHE A CG 1 ATOM 1524 C CD1 . PHE A 1 198 ? 13.729 4.660 24.634 1.00 23.64 ? 194 PHE A CD1 1 ATOM 1525 C CD2 . PHE A 1 198 ? 12.713 6.289 26.075 1.00 19.08 ? 194 PHE A CD2 1 ATOM 1526 C CE1 . PHE A 1 198 ? 12.559 4.558 23.899 1.00 25.19 ? 194 PHE A CE1 1 ATOM 1527 C CE2 . PHE A 1 198 ? 11.539 6.225 25.330 1.00 19.42 ? 194 PHE A CE2 1 ATOM 1528 C CZ . PHE A 1 198 ? 11.436 5.345 24.253 1.00 24.40 ? 194 PHE A CZ 1 ATOM 1529 N N . VAL A 1 199 ? 15.026 8.208 24.288 1.00 16.66 ? 195 VAL A N 1 ATOM 1530 C CA . VAL A 1 199 ? 14.063 9.282 24.038 1.00 17.37 ? 195 VAL A CA 1 ATOM 1531 C C . VAL A 1 199 ? 13.132 8.764 22.948 1.00 18.19 ? 195 VAL A C 1 ATOM 1532 O O . VAL A 1 199 ? 13.575 8.192 21.916 1.00 17.83 ? 195 VAL A O 1 ATOM 1533 C CB . VAL A 1 199 ? 14.748 10.596 23.554 1.00 17.16 ? 195 VAL A CB 1 ATOM 1534 C CG1 . VAL A 1 199 ? 13.716 11.679 23.364 1.00 18.82 ? 195 VAL A CG1 1 ATOM 1535 C CG2 . VAL A 1 199 ? 15.825 11.067 24.536 1.00 19.82 ? 195 VAL A CG2 1 ATOM 1536 N N . ALA A 1 200 ? 11.825 8.992 23.113 1.00 16.80 ? 196 ALA A N 1 ATOM 1537 C CA . ALA A 1 200 ? 10.882 8.368 22.212 1.00 18.24 ? 196 ALA A CA 1 ATOM 1538 C C . ALA A 1 200 ? 10.868 8.881 20.792 1.00 20.34 ? 196 ALA A C 1 ATOM 1539 O O . ALA A 1 200 ? 10.562 8.131 19.854 1.00 23.52 ? 196 ALA A O 1 ATOM 1540 C CB . ALA A 1 200 ? 9.431 8.414 22.806 1.00 19.10 ? 196 ALA A CB 1 ATOM 1541 N N . GLY A 1 201 ? 11.189 10.143 20.609 1.00 19.92 ? 197 GLY A N 1 ATOM 1542 C CA . GLY A 1 201 ? 11.115 10.763 19.298 1.00 18.68 ? 197 GLY A CA 1 ATOM 1543 C C . GLY A 1 201 ? 10.972 12.274 19.407 1.00 18.81 ? 197 GLY A C 1 ATOM 1544 O O . GLY A 1 201 ? 11.327 12.875 20.449 1.00 19.46 ? 197 GLY A O 1 ATOM 1545 N N . LYS A 1 202 ? 10.506 12.869 18.317 1.00 19.23 ? 198 LYS A N 1 ATOM 1546 C CA . LYS A 1 202 ? 10.634 14.324 18.103 1.00 18.85 ? 198 LYS A CA 1 ATOM 1547 C C . LYS A 1 202 ? 9.752 15.153 19.016 1.00 19.56 ? 198 LYS A C 1 ATOM 1548 O O . LYS A 1 202 ? 9.956 16.374 19.110 1.00 18.52 ? 198 LYS A O 1 ATOM 1549 C CB . LYS A 1 202 ? 10.430 14.719 16.631 1.00 19.84 ? 198 LYS A CB 1 ATOM 1550 C CG . LYS A 1 202 ? 8.974 14.576 16.181 1.00 20.29 ? 198 LYS A CG 1 ATOM 1551 C CD . LYS A 1 202 ? 8.864 14.694 14.661 1.00 24.14 ? 198 LYS A CD 1 ATOM 1552 C CE . LYS A 1 202 ? 7.389 14.563 14.293 1.00 31.18 ? 198 LYS A CE 1 ATOM 1553 N NZ . LYS A 1 202 ? 7.063 15.620 13.326 1.00 36.44 ? 198 LYS A NZ 1 ATOM 1554 N N . ASN A 1 203 ? 8.772 14.528 19.688 1.00 18.45 ? 199 ASN A N 1 ATOM 1555 C CA . ASN A 1 203 ? 7.968 15.282 20.635 1.00 18.99 ? 199 ASN A CA 1 ATOM 1556 C C . ASN A 1 203 ? 8.395 15.164 22.103 1.00 18.14 ? 199 ASN A C 1 ATOM 1557 O O . ASN A 1 203 ? 7.685 15.643 23.039 1.00 18.47 ? 199 ASN A O 1 ATOM 1558 C CB . ASN A 1 203 ? 6.500 14.892 20.460 1.00 20.67 ? 199 ASN A CB 1 ATOM 1559 C CG . ASN A 1 203 ? 6.020 15.099 19.031 1.00 24.49 ? 199 ASN A CG 1 ATOM 1560 O OD1 . ASN A 1 203 ? 5.665 14.147 18.334 1.00 33.66 ? 199 ASN A OD1 1 ATOM 1561 N ND2 . ASN A 1 203 ? 6.019 16.314 18.590 1.00 25.39 ? 199 ASN A ND2 1 ATOM 1562 N N . LYS A 1 204 ? 9.544 14.515 22.343 1.00 16.75 ? 200 LYS A N 1 ATOM 1563 C CA . LYS A 1 204 ? 10.104 14.292 23.657 1.00 15.41 ? 200 LYS A CA 1 ATOM 1564 C C . LYS A 1 204 ? 11.521 14.895 23.625 1.00 14.26 ? 200 LYS A C 1 ATOM 1565 O O . LYS A 1 204 ? 12.012 15.309 22.569 1.00 15.64 ? 200 LYS A O 1 ATOM 1566 C CB . LYS A 1 204 ? 10.192 12.784 23.982 1.00 15.40 ? 200 LYS A CB 1 ATOM 1567 C CG . LYS A 1 204 ? 8.782 12.182 24.115 1.00 16.62 ? 200 LYS A CG 1 ATOM 1568 C CD . LYS A 1 204 ? 8.054 12.782 25.358 1.00 19.10 ? 200 LYS A CD 1 ATOM 1569 C CE . LYS A 1 204 ? 6.837 11.926 25.703 1.00 20.88 ? 200 LYS A CE 1 ATOM 1570 N NZ . LYS A 1 204 ? 6.034 12.586 26.826 1.00 19.65 ? 200 LYS A NZ 1 ATOM 1571 N N . VAL A 1 205 ? 12.115 15.001 24.802 1.00 14.78 ? 201 VAL A N 1 ATOM 1572 C CA . VAL A 1 205 ? 13.494 15.582 24.921 1.00 13.65 ? 201 VAL A CA 1 ATOM 1573 C C . VAL A 1 205 ? 14.384 14.654 25.686 1.00 14.25 ? 201 VAL A C 1 ATOM 1574 O O . VAL A 1 205 ? 13.938 13.834 26.504 1.00 14.29 ? 201 VAL A O 1 ATOM 1575 C CB . VAL A 1 205 ? 13.497 17.014 25.602 1.00 12.94 ? 201 VAL A CB 1 ATOM 1576 C CG1 . VAL A 1 205 ? 12.663 18.011 24.769 1.00 14.38 ? 201 VAL A CG1 1 ATOM 1577 C CG2 . VAL A 1 205 ? 13.002 16.932 27.072 1.00 15.07 ? 201 VAL A CG2 1 ATOM 1578 N N . ALA A 1 206 ? 15.708 14.733 25.414 1.00 13.22 ? 202 ALA A N 1 ATOM 1579 C CA . ALA A 1 206 ? 16.692 14.062 26.273 1.00 13.62 ? 202 ALA A CA 1 ATOM 1580 C C . ALA A 1 206 ? 16.686 14.709 27.660 1.00 14.28 ? 202 ALA A C 1 ATOM 1581 O O . ALA A 1 206 ? 16.528 15.944 27.758 1.00 13.78 ? 202 ALA A O 1 ATOM 1582 C CB . ALA A 1 206 ? 18.071 14.187 25.639 1.00 14.27 ? 202 ALA A CB 1 ATOM 1583 N N . ALA A 1 207 ? 16.772 13.905 28.708 1.00 13.63 ? 203 ALA A N 1 ATOM 1584 C CA . ALA A 1 207 ? 16.840 14.384 30.073 1.00 13.25 ? 203 ALA A CA 1 ATOM 1585 C C . ALA A 1 207 ? 18.238 14.275 30.662 1.00 13.93 ? 203 ALA A C 1 ATOM 1586 O O . ALA A 1 207 ? 19.156 13.782 29.956 1.00 15.63 ? 203 ALA A O 1 ATOM 1587 C CB . ALA A 1 207 ? 15.819 13.641 30.957 1.00 15.39 ? 203 ALA A CB 1 ATOM 1588 N N . CYS A 1 208 ? 18.391 14.747 31.892 1.00 13.92 ? 204 CYS A N 1 ATOM 1589 C CA . CYS A 1 208 ? 19.695 14.842 32.548 1.00 14.32 ? 204 CYS A CA 1 ATOM 1590 C C . CYS A 1 208 ? 19.536 14.735 34.028 1.00 14.80 ? 204 CYS A C 1 ATOM 1591 O O . CYS A 1 208 ? 19.057 15.665 34.659 1.00 15.10 ? 204 CYS A O 1 ATOM 1592 C CB . CYS A 1 208 ? 20.284 16.232 32.243 1.00 13.29 ? 204 CYS A CB 1 ATOM 1593 S SG . CYS A 1 208 ? 21.980 16.414 32.917 1.00 15.90 ? 204 CYS A SG 1 ATOM 1594 N N . ALA A 1 209 ? 19.977 13.603 34.606 1.00 15.33 ? 205 ALA A N 1 ATOM 1595 C CA . ALA A 1 209 ? 19.975 13.472 36.055 1.00 14.75 ? 205 ALA A CA 1 ATOM 1596 C C . ALA A 1 209 ? 21.152 14.253 36.574 1.00 15.12 ? 205 ALA A C 1 ATOM 1597 O O . ALA A 1 209 ? 22.311 14.010 36.137 1.00 14.62 ? 205 ALA A O 1 ATOM 1598 C CB . ALA A 1 209 ? 20.102 11.983 36.446 1.00 15.72 ? 205 ALA A CB 1 ATOM 1599 N N . LYS A 1 210 ? 20.941 15.186 37.484 1.00 14.56 ? 206 LYS A N 1 ATOM 1600 C CA . LYS A 1 210 ? 22.057 15.997 37.950 1.00 14.47 ? 206 LYS A CA 1 ATOM 1601 C C . LYS A 1 210 ? 21.963 16.318 39.464 1.00 15.12 ? 206 LYS A C 1 ATOM 1602 O O . LYS A 1 210 ? 20.840 16.202 39.987 1.00 15.20 ? 206 LYS A O 1 ATOM 1603 C CB . LYS A 1 210 ? 22.166 17.302 37.118 1.00 14.08 ? 206 LYS A CB 1 ATOM 1604 C CG . LYS A 1 210 ? 20.984 18.285 37.366 1.00 15.09 ? 206 LYS A CG 1 ATOM 1605 C CD . LYS A 1 210 ? 21.083 19.499 36.375 1.00 13.88 ? 206 LYS A CD 1 ATOM 1606 C CE . LYS A 1 210 ? 20.127 20.642 36.894 1.00 13.47 ? 206 LYS A CE 1 ATOM 1607 N NZ . LYS A 1 210 ? 20.130 21.807 35.897 1.00 14.05 ? 206 LYS A NZ 1 ATOM 1608 N N . HIS A 1 211 ? 23.015 16.714 40.184 1.00 14.24 ? 207 HIS A N 1 ATOM 1609 C CA . HIS A 1 211 ? 24.412 16.786 39.710 1.00 15.90 ? 207 HIS A CA 1 ATOM 1610 C C . HIS A 1 211 ? 25.162 15.655 40.436 1.00 16.53 ? 207 HIS A C 1 ATOM 1611 O O . HIS A 1 211 ? 25.100 15.558 41.670 1.00 17.22 ? 207 HIS A O 1 ATOM 1612 C CB . HIS A 1 211 ? 25.043 18.136 40.044 1.00 15.71 ? 207 HIS A CB 1 ATOM 1613 C CG . HIS A 1 211 ? 24.184 19.307 39.678 1.00 17.17 ? 207 HIS A CG 1 ATOM 1614 N ND1 . HIS A 1 211 ? 23.180 19.775 40.511 1.00 17.95 ? 207 HIS A ND1 1 ATOM 1615 C CD2 . HIS A 1 211 ? 24.169 20.089 38.563 1.00 15.96 ? 207 HIS A CD2 1 ATOM 1616 C CE1 . HIS A 1 211 ? 22.606 20.831 39.922 1.00 15.77 ? 207 HIS A CE1 1 ATOM 1617 N NE2 . HIS A 1 211 ? 23.188 21.040 38.745 1.00 16.27 ? 207 HIS A NE2 1 ATOM 1618 N N . PHE A 1 212 ? 25.768 14.762 39.652 1.00 16.76 ? 208 PHE A N 1 ATOM 1619 C CA . PHE A 1 212 ? 26.359 13.521 40.205 1.00 16.61 ? 208 PHE A CA 1 ATOM 1620 C C . PHE A 1 212 ? 27.687 13.798 40.924 1.00 17.88 ? 208 PHE A C 1 ATOM 1621 O O . PHE A 1 212 ? 28.616 14.358 40.323 1.00 17.54 ? 208 PHE A O 1 ATOM 1622 C CB . PHE A 1 212 ? 26.607 12.595 39.026 1.00 15.68 ? 208 PHE A CB 1 ATOM 1623 C CG . PHE A 1 212 ? 27.168 11.251 39.406 1.00 19.30 ? 208 PHE A CG 1 ATOM 1624 C CD1 . PHE A 1 212 ? 26.310 10.234 39.754 1.00 16.16 ? 208 PHE A CD1 1 ATOM 1625 C CD2 . PHE A 1 212 ? 28.559 11.031 39.350 1.00 20.59 ? 208 PHE A CD2 1 ATOM 1626 C CE1 . PHE A 1 212 ? 26.762 8.963 40.091 1.00 20.38 ? 208 PHE A CE1 1 ATOM 1627 C CE2 . PHE A 1 212 ? 29.052 9.721 39.685 1.00 19.71 ? 208 PHE A CE2 1 ATOM 1628 C CZ . PHE A 1 212 ? 28.158 8.721 40.053 1.00 19.94 ? 208 PHE A CZ 1 ATOM 1629 N N . VAL A 1 213 ? 27.814 13.459 42.228 1.00 17.24 ? 209 VAL A N 1 ATOM 1630 C CA . VAL A 1 213 ? 26.751 12.957 43.124 1.00 18.09 ? 209 VAL A CA 1 ATOM 1631 C C . VAL A 1 213 ? 27.035 13.572 44.499 1.00 17.85 ? 209 VAL A C 1 ATOM 1632 O O . VAL A 1 213 ? 28.159 13.953 44.804 1.00 18.53 ? 209 VAL A O 1 ATOM 1633 C CB . VAL A 1 213 ? 26.765 11.424 43.207 1.00 17.90 ? 209 VAL A CB 1 ATOM 1634 C CG1 . VAL A 1 213 ? 28.183 10.948 43.636 1.00 18.64 ? 209 VAL A CG1 1 ATOM 1635 C CG2 . VAL A 1 213 ? 25.745 10.881 44.198 1.00 17.67 ? 209 VAL A CG2 1 ATOM 1636 N N . GLY A 1 214 ? 25.989 13.699 45.338 1.00 17.82 ? 210 GLY A N 1 ATOM 1637 C CA . GLY A 1 214 ? 26.121 14.348 46.649 1.00 17.62 ? 210 GLY A CA 1 ATOM 1638 C C . GLY A 1 214 ? 26.149 15.872 46.655 1.00 18.05 ? 210 GLY A C 1 ATOM 1639 O O . GLY A 1 214 ? 26.579 16.516 47.601 1.00 18.22 ? 210 GLY A O 1 ATOM 1640 N N . ASP A 1 215 ? 25.658 16.493 45.552 1.00 17.65 ? 211 ASP A N 1 ATOM 1641 C CA . ASP A 1 215 ? 25.480 17.917 45.558 1.00 17.33 ? 211 ASP A CA 1 ATOM 1642 C C . ASP A 1 215 ? 24.637 18.524 46.722 1.00 15.45 ? 211 ASP A C 1 ATOM 1643 O O . ASP A 1 215 ? 24.888 19.643 47.127 1.00 17.81 ? 211 ASP A O 1 ATOM 1644 C CB . ASP A 1 215 ? 24.905 18.394 44.190 1.00 16.82 ? 211 ASP A CB 1 ATOM 1645 C CG . ASP A 1 215 ? 23.691 17.609 43.717 1.00 16.81 ? 211 ASP A CG 1 ATOM 1646 O OD1 . ASP A 1 215 ? 23.378 16.494 44.155 1.00 16.58 ? 211 ASP A OD1 1 ATOM 1647 O OD2 . ASP A 1 215 ? 23.011 18.109 42.787 1.00 16.77 ? 211 ASP A OD2 1 ATOM 1648 N N . GLY A 1 216 ? 23.724 17.721 47.232 1.00 18.44 ? 212 GLY A N 1 ATOM 1649 C CA . GLY A 1 216 ? 22.846 18.155 48.359 1.00 16.83 ? 212 GLY A CA 1 ATOM 1650 C C . GLY A 1 216 ? 23.427 17.834 49.744 1.00 19.50 ? 212 GLY A C 1 ATOM 1651 O O . GLY A 1 216 ? 22.771 18.044 50.756 1.00 19.64 ? 212 GLY A O 1 ATOM 1652 N N . GLY A 1 217 ? 24.684 17.400 49.755 1.00 19.40 ? 213 GLY A N 1 ATOM 1653 C CA . GLY A 1 217 ? 25.320 16.903 51.006 1.00 20.40 ? 213 GLY A CA 1 ATOM 1654 C C . GLY A 1 217 ? 26.435 17.779 51.496 1.00 21.10 ? 213 GLY A C 1 ATOM 1655 O O . GLY A 1 217 ? 27.214 17.375 52.410 1.00 22.85 ? 213 GLY A O 1 ATOM 1656 N N . THR A 1 218 ? 26.591 18.980 50.947 1.00 20.49 ? 214 THR A N 1 ATOM 1657 C CA . THR A 1 218 ? 27.811 19.745 51.212 1.00 20.99 ? 214 THR A CA 1 ATOM 1658 C C . THR A 1 218 ? 27.838 20.320 52.636 1.00 22.34 ? 214 THR A C 1 ATOM 1659 O O . THR A 1 218 ? 26.776 20.612 53.239 1.00 21.98 ? 214 THR A O 1 ATOM 1660 C CB . THR A 1 218 ? 28.042 20.904 50.212 1.00 20.70 ? 214 THR A CB 1 ATOM 1661 O OG1 . THR A 1 218 ? 26.928 21.824 50.287 1.00 20.99 ? 214 THR A OG1 1 ATOM 1662 C CG2 . THR A 1 218 ? 28.205 20.373 48.774 1.00 19.38 ? 214 THR A CG2 1 ATOM 1663 N N . VAL A 1 219 ? 29.048 20.499 53.168 1.00 23.01 ? 215 VAL A N 1 ATOM 1664 C CA . VAL A 1 219 ? 29.232 21.140 54.483 1.00 23.90 ? 215 VAL A CA 1 ATOM 1665 C C . VAL A 1 219 ? 28.473 22.486 54.607 1.00 22.64 ? 215 VAL A C 1 ATOM 1666 O O . VAL A 1 219 ? 28.689 23.412 53.816 1.00 22.07 ? 215 VAL A O 1 ATOM 1667 C CB . VAL A 1 219 ? 30.768 21.318 54.799 1.00 23.80 ? 215 VAL A CB 1 ATOM 1668 C CG1 A VAL A 1 219 ? 31.024 22.330 56.011 0.60 24.37 ? 215 VAL A CG1 1 ATOM 1669 C CG1 B VAL A 1 219 ? 31.421 22.310 53.900 0.40 22.52 ? 215 VAL A CG1 1 ATOM 1670 C CG2 A VAL A 1 219 ? 31.457 19.972 54.947 0.60 24.64 ? 215 VAL A CG2 1 ATOM 1671 C CG2 B VAL A 1 219 ? 30.958 21.655 56.296 0.40 24.94 ? 215 VAL A CG2 1 ATOM 1672 N N . ASP A 1 220 ? 27.590 22.558 55.620 1.00 23.33 ? 216 ASP A N 1 ATOM 1673 C CA . ASP A 1 220 ? 26.838 23.770 55.959 1.00 22.76 ? 216 ASP A CA 1 ATOM 1674 C C . ASP A 1 220 ? 25.951 24.235 54.766 1.00 21.24 ? 216 ASP A C 1 ATOM 1675 O O . ASP A 1 220 ? 25.609 25.393 54.711 1.00 21.89 ? 216 ASP A O 1 ATOM 1676 C CB . ASP A 1 220 ? 27.721 24.919 56.362 1.00 23.91 ? 216 ASP A CB 1 ATOM 1677 C CG . ASP A 1 220 ? 28.457 24.660 57.706 1.00 28.42 ? 216 ASP A CG 1 ATOM 1678 O OD1 . ASP A 1 220 ? 28.081 23.697 58.401 1.00 31.29 ? 216 ASP A OD1 1 ATOM 1679 O OD2 . ASP A 1 220 ? 29.381 25.446 57.977 1.00 30.76 ? 216 ASP A OD2 1 ATOM 1680 N N . GLY A 1 221 ? 25.703 23.326 53.836 1.00 20.95 ? 217 GLY A N 1 ATOM 1681 C CA . GLY A 1 221 ? 24.960 23.668 52.590 1.00 21.69 ? 217 GLY A CA 1 ATOM 1682 C C . GLY A 1 221 ? 25.695 24.683 51.726 1.00 22.60 ? 217 GLY A C 1 ATOM 1683 O O . GLY A 1 221 ? 25.082 25.434 50.952 1.00 22.27 ? 217 GLY A O 1 ATOM 1684 N N . ILE A 1 222 ? 27.033 24.751 51.824 1.00 19.89 ? 218 ILE A N 1 ATOM 1685 C CA . ILE A 1 222 ? 27.775 25.705 51.000 1.00 19.29 ? 218 ILE A CA 1 ATOM 1686 C C . ILE A 1 222 ? 27.804 25.146 49.552 1.00 19.33 ? 218 ILE A C 1 ATOM 1687 O O . ILE A 1 222 ? 28.198 24.011 49.317 1.00 19.27 ? 218 ILE A O 1 ATOM 1688 C CB . ILE A 1 222 ? 29.230 25.897 51.524 1.00 20.67 ? 218 ILE A CB 1 ATOM 1689 C CG1 . ILE A 1 222 ? 29.193 26.530 52.912 1.00 21.34 ? 218 ILE A CG1 1 ATOM 1690 C CG2 . ILE A 1 222 ? 30.023 26.787 50.562 1.00 19.62 ? 218 ILE A CG2 1 ATOM 1691 C CD1 . ILE A 1 222 ? 30.507 26.131 53.665 1.00 24.54 ? 218 ILE A CD1 1 ATOM 1692 N N . ASN A 1 223 ? 27.317 25.957 48.619 1.00 19.49 ? 219 ASN A N 1 ATOM 1693 C CA . ASN A 1 223 ? 27.133 25.452 47.260 1.00 19.29 ? 219 ASN A CA 1 ATOM 1694 C C . ASN A 1 223 ? 28.529 25.138 46.657 1.00 18.32 ? 219 ASN A C 1 ATOM 1695 O O . ASN A 1 223 ? 29.440 25.911 46.818 1.00 19.74 ? 219 ASN A O 1 ATOM 1696 C CB . ASN A 1 223 ? 26.399 26.561 46.459 1.00 18.75 ? 219 ASN A CB 1 ATOM 1697 C CG . ASN A 1 223 ? 26.073 26.135 45.024 1.00 16.36 ? 219 ASN A CG 1 ATOM 1698 O OD1 . ASN A 1 223 ? 26.273 26.947 44.068 1.00 21.20 ? 219 ASN A OD1 1 ATOM 1699 N ND2 . ASN A 1 223 ? 25.647 24.929 44.854 1.00 14.96 ? 219 ASN A ND2 1 ATOM 1700 N N . GLU A 1 224 ? 28.611 24.007 45.964 1.00 18.31 ? 220 GLU A N 1 ATOM 1701 C CA . GLU A 1 224 ? 29.811 23.546 45.230 1.00 19.33 ? 220 GLU A CA 1 ATOM 1702 C C . GLU A 1 224 ? 30.889 23.059 46.183 1.00 21.25 ? 220 GLU A C 1 ATOM 1703 O O . GLU A 1 224 ? 31.989 22.796 45.736 1.00 21.70 ? 220 GLU A O 1 ATOM 1704 C CB . GLU A 1 224 ? 30.401 24.626 44.332 1.00 19.56 ? 220 GLU A CB 1 ATOM 1705 C CG . GLU A 1 224 ? 29.371 25.260 43.362 1.00 18.71 ? 220 GLU A CG 1 ATOM 1706 C CD . GLU A 1 224 ? 29.988 26.158 42.325 1.00 23.13 ? 220 GLU A CD 1 ATOM 1707 O OE1 . GLU A 1 224 ? 31.257 26.157 42.126 1.00 22.06 ? 220 GLU A OE1 1 ATOM 1708 O OE2 . GLU A 1 224 ? 29.210 26.920 41.689 1.00 21.10 ? 220 GLU A OE2 1 ATOM 1709 N N . ASN A 1 225 ? 30.542 22.862 47.452 1.00 21.49 ? 221 ASN A N 1 ATOM 1710 C CA . ASN A 1 225 ? 31.607 22.600 48.441 1.00 21.25 ? 221 ASN A CA 1 ATOM 1711 C C . ASN A 1 225 ? 31.834 21.103 48.624 1.00 20.69 ? 221 ASN A C 1 ATOM 1712 O O . ASN A 1 225 ? 31.596 20.286 47.728 1.00 20.81 ? 221 ASN A O 1 ATOM 1713 C CB . ASN A 1 225 ? 31.322 23.398 49.735 1.00 21.10 ? 221 ASN A CB 1 ATOM 1714 C CG . ASN A 1 225 ? 32.611 23.779 50.482 1.00 24.81 ? 221 ASN A CG 1 ATOM 1715 O OD1 . ASN A 1 225 ? 32.940 23.141 51.477 1.00 27.30 ? 221 ASN A OD1 1 ATOM 1716 N ND2 . ASN A 1 225 ? 33.302 24.790 50.002 1.00 26.85 ? 221 ASN A ND2 1 ATOM 1717 N N . ASN A 1 226 ? 32.358 20.728 49.807 1.00 21.80 ? 222 ASN A N 1 ATOM 1718 C CA . ASN A 1 226 ? 32.719 19.343 50.063 1.00 22.61 ? 222 ASN A CA 1 ATOM 1719 C C . ASN A 1 226 ? 31.602 18.575 50.759 1.00 22.34 ? 222 ASN A C 1 ATOM 1720 O O . ASN A 1 226 ? 31.063 19.070 51.754 1.00 23.58 ? 222 ASN A O 1 ATOM 1721 C CB . ASN A 1 226 ? 33.992 19.355 50.953 1.00 23.68 ? 222 ASN A CB 1 ATOM 1722 C CG . ASN A 1 226 ? 34.694 18.026 51.005 1.00 23.98 ? 222 ASN A CG 1 ATOM 1723 O OD1 . ASN A 1 226 ? 34.475 17.121 50.214 1.00 23.80 ? 222 ASN A OD1 1 ATOM 1724 N ND2 . ASN A 1 226 ? 35.599 17.892 52.020 1.00 28.10 ? 222 ASN A ND2 1 ATOM 1725 N N . THR A 1 227 ? 31.308 17.361 50.318 1.00 21.82 ? 223 THR A N 1 ATOM 1726 C CA . THR A 1 227 ? 30.353 16.472 50.966 1.00 23.16 ? 223 THR A CA 1 ATOM 1727 C C . THR A 1 227 ? 31.210 15.461 51.706 1.00 24.50 ? 223 THR A C 1 ATOM 1728 O O . THR A 1 227 ? 31.859 14.609 51.060 1.00 23.14 ? 223 THR A O 1 ATOM 1729 C CB . THR A 1 227 ? 29.453 15.772 49.908 1.00 22.73 ? 223 THR A CB 1 ATOM 1730 O OG1 . THR A 1 227 ? 28.690 16.822 49.324 1.00 24.96 ? 223 THR A OG1 1 ATOM 1731 C CG2 . THR A 1 227 ? 28.478 14.791 50.478 1.00 22.32 ? 223 THR A CG2 1 ATOM 1732 N N . ILE A 1 228 ? 31.176 15.576 53.039 1.00 25.04 ? 224 ILE A N 1 ATOM 1733 C CA . ILE A 1 228 ? 31.985 14.706 53.940 1.00 27.05 ? 224 ILE A CA 1 ATOM 1734 C C . ILE A 1 228 ? 31.079 13.636 54.499 1.00 27.23 ? 224 ILE A C 1 ATOM 1735 O O . ILE A 1 228 ? 30.287 13.879 55.414 1.00 28.69 ? 224 ILE A O 1 ATOM 1736 C CB . ILE A 1 228 ? 32.680 15.544 55.041 1.00 27.50 ? 224 ILE A CB 1 ATOM 1737 C CG1 . ILE A 1 228 ? 33.581 16.616 54.414 1.00 27.76 ? 224 ILE A CG1 1 ATOM 1738 C CG2 . ILE A 1 228 ? 33.493 14.576 56.003 1.00 28.44 ? 224 ILE A CG2 1 ATOM 1739 C CD1 . ILE A 1 228 ? 34.152 17.677 55.351 1.00 29.98 ? 224 ILE A CD1 1 ATOM 1740 N N . ILE A 1 229 ? 31.155 12.447 53.925 1.00 26.83 ? 225 ILE A N 1 ATOM 1741 C CA . ILE A 1 229 ? 30.304 11.345 54.289 1.00 28.23 ? 225 ILE A CA 1 ATOM 1742 C C . ILE A 1 229 ? 30.975 10.056 53.847 1.00 29.39 ? 225 ILE A C 1 ATOM 1743 O O . ILE A 1 229 ? 31.657 10.014 52.807 1.00 28.27 ? 225 ILE A O 1 ATOM 1744 C CB . ILE A 1 229 ? 28.845 11.480 53.693 1.00 28.97 ? 225 ILE A CB 1 ATOM 1745 C CG1 . ILE A 1 229 ? 27.880 10.479 54.329 1.00 28.53 ? 225 ILE A CG1 1 ATOM 1746 C CG2 . ILE A 1 229 ? 28.854 11.262 52.136 1.00 28.27 ? 225 ILE A CG2 1 ATOM 1747 C CD1 . ILE A 1 229 ? 26.365 10.806 54.055 1.00 29.10 ? 225 ILE A CD1 1 ATOM 1748 N N . ASN A 1 230 ? 30.830 8.986 54.632 1.00 29.33 ? 226 ASN A N 1 ATOM 1749 C CA . ASN A 1 230 ? 31.404 7.716 54.190 1.00 29.72 ? 226 ASN A CA 1 ATOM 1750 C C . ASN A 1 230 ? 30.658 7.078 53.015 1.00 30.10 ? 226 ASN A C 1 ATOM 1751 O O . ASN A 1 230 ? 29.532 7.492 52.658 1.00 29.49 ? 226 ASN A O 1 ATOM 1752 C CB . ASN A 1 230 ? 31.605 6.724 55.373 1.00 29.92 ? 226 ASN A CB 1 ATOM 1753 C CG . ASN A 1 230 ? 30.296 6.207 55.968 1.00 32.61 ? 226 ASN A CG 1 ATOM 1754 O OD1 . ASN A 1 230 ? 29.198 6.331 55.402 1.00 33.09 ? 226 ASN A OD1 1 ATOM 1755 N ND2 . ASN A 1 230 ? 30.421 5.565 57.142 1.00 33.45 ? 226 ASN A ND2 1 ATOM 1756 N N . ARG A 1 231 ? 31.276 6.104 52.361 1.00 30.27 ? 227 ARG A N 1 ATOM 1757 C CA . ARG A 1 231 ? 30.651 5.509 51.180 1.00 29.62 ? 227 ARG A CA 1 ATOM 1758 C C . ARG A 1 231 ? 29.279 4.950 51.434 1.00 30.28 ? 227 ARG A C 1 ATOM 1759 O O . ARG A 1 231 ? 28.405 4.993 50.572 1.00 28.59 ? 227 ARG A O 1 ATOM 1760 C CB . ARG A 1 231 ? 31.539 4.427 50.565 1.00 30.94 ? 227 ARG A CB 1 ATOM 1761 C CG . ARG A 1 231 ? 31.130 4.006 49.162 1.00 31.74 ? 227 ARG A CG 1 ATOM 1762 C CD . ARG A 1 231 ? 32.112 2.968 48.662 1.00 36.44 ? 227 ARG A CD 1 ATOM 1763 N NE . ARG A 1 231 ? 32.032 2.714 47.227 1.00 38.54 ? 227 ARG A NE 1 ATOM 1764 C CZ . ARG A 1 231 ? 31.237 1.808 46.660 1.00 42.01 ? 227 ARG A CZ 1 ATOM 1765 N NH1 . ARG A 1 231 ? 30.415 1.055 47.401 1.00 42.36 ? 227 ARG A NH1 1 ATOM 1766 N NH2 . ARG A 1 231 ? 31.255 1.663 45.337 1.00 42.80 ? 227 ARG A NH2 1 ATOM 1767 N N . GLU A 1 232 ? 29.088 4.372 52.617 1.00 29.78 ? 228 GLU A N 1 ATOM 1768 C CA . GLU A 1 232 ? 27.798 3.827 52.971 1.00 30.57 ? 228 GLU A CA 1 ATOM 1769 C C . GLU A 1 232 ? 26.710 4.926 52.919 1.00 28.28 ? 228 GLU A C 1 ATOM 1770 O O . GLU A 1 232 ? 25.639 4.680 52.386 1.00 30.07 ? 228 GLU A O 1 ATOM 1771 C CB . GLU A 1 232 ? 27.862 3.194 54.360 1.00 31.23 ? 228 GLU A CB 1 ATOM 1772 C CG . GLU A 1 232 ? 26.795 2.163 54.570 1.00 35.56 ? 228 GLU A CG 1 ATOM 1773 C CD . GLU A 1 232 ? 26.772 1.682 56.016 1.00 42.47 ? 228 GLU A CD 1 ATOM 1774 O OE1 . GLU A 1 232 ? 27.852 1.654 56.654 1.00 44.78 ? 228 GLU A OE1 1 ATOM 1775 O OE2 . GLU A 1 232 ? 25.670 1.368 56.512 1.00 45.66 ? 228 GLU A OE2 1 ATOM 1776 N N . GLY A 1 233 ? 27.015 6.077 53.505 1.00 28.23 ? 229 GLY A N 1 ATOM 1777 C CA . GLY A 1 233 ? 26.093 7.241 53.568 1.00 27.07 ? 229 GLY A CA 1 ATOM 1778 C C . GLY A 1 233 ? 25.875 7.803 52.170 1.00 26.77 ? 229 GLY A C 1 ATOM 1779 O O . GLY A 1 233 ? 24.724 8.009 51.762 1.00 25.99 ? 229 GLY A O 1 ATOM 1780 N N . LEU A 1 234 ? 26.968 7.987 51.424 1.00 25.67 ? 230 LEU A N 1 ATOM 1781 C CA . LEU A 1 234 ? 26.824 8.413 50.007 1.00 25.30 ? 230 LEU A CA 1 ATOM 1782 C C . LEU A 1 234 ? 25.884 7.483 49.255 1.00 25.12 ? 230 LEU A C 1 ATOM 1783 O O . LEU A 1 234 ? 25.004 7.952 48.510 1.00 26.07 ? 230 LEU A O 1 ATOM 1784 C CB . LEU A 1 234 ? 28.175 8.504 49.293 1.00 24.90 ? 230 LEU A CB 1 ATOM 1785 C CG . LEU A 1 234 ? 28.082 9.133 47.877 1.00 24.36 ? 230 LEU A CG 1 ATOM 1786 C CD1 . LEU A 1 234 ? 28.146 10.622 47.996 1.00 25.08 ? 230 LEU A CD1 1 ATOM 1787 C CD2 . LEU A 1 234 ? 29.261 8.603 47.059 1.00 24.48 ? 230 LEU A CD2 1 ATOM 1788 N N . MET A 1 235 ? 26.036 6.162 49.413 1.00 23.95 ? 231 MET A N 1 ATOM 1789 C CA . MET A 1 235 ? 25.241 5.203 48.703 1.00 24.59 ? 231 MET A CA 1 ATOM 1790 C C . MET A 1 235 ? 23.816 5.069 49.202 1.00 24.66 ? 231 MET A C 1 ATOM 1791 O O . MET A 1 235 ? 22.943 4.648 48.441 1.00 26.63 ? 231 MET A O 1 ATOM 1792 C CB . MET A 1 235 ? 25.915 3.809 48.704 1.00 25.63 ? 231 MET A CB 1 ATOM 1793 C CG . MET A 1 235 ? 27.237 3.804 47.951 1.00 25.75 ? 231 MET A CG 1 ATOM 1794 S SD . MET A 1 235 ? 27.009 4.146 46.176 1.00 30.37 ? 231 MET A SD 1 ATOM 1795 C CE . MET A 1 235 ? 28.735 4.306 45.687 1.00 29.01 ? 231 MET A CE 1 ATOM 1796 N N . ASN A 1 236 ? 23.590 5.409 50.476 1.00 25.98 ? 232 ASN A N 1 ATOM 1797 C CA . ASN A 1 236 ? 22.285 5.251 51.101 1.00 27.01 ? 232 ASN A CA 1 ATOM 1798 C C . ASN A 1 236 ? 21.397 6.488 50.896 1.00 25.03 ? 232 ASN A C 1 ATOM 1799 O O . ASN A 1 236 ? 20.177 6.338 50.805 1.00 26.19 ? 232 ASN A O 1 ATOM 1800 C CB . ASN A 1 236 ? 22.458 5.004 52.613 1.00 28.06 ? 232 ASN A CB 1 ATOM 1801 C CG A ASN A 1 236 ? 21.136 4.842 53.351 0.60 31.19 ? 232 ASN A CG 1 ATOM 1802 C CG B ASN A 1 236 ? 22.632 3.545 52.952 0.40 28.87 ? 232 ASN A CG 1 ATOM 1803 O OD1 A ASN A 1 236 ? 20.372 3.892 53.115 0.60 37.71 ? 232 ASN A OD1 1 ATOM 1804 O OD1 B ASN A 1 236 ? 22.435 2.664 52.113 0.40 31.19 ? 232 ASN A OD1 1 ATOM 1805 N ND2 A ASN A 1 236 ? 20.865 5.763 54.265 0.60 36.71 ? 232 ASN A ND2 1 ATOM 1806 N ND2 B ASN A 1 236 ? 22.987 3.280 54.204 0.40 28.65 ? 232 ASN A ND2 1 ATOM 1807 N N . ILE A 1 237 ? 22.038 7.653 50.803 1.00 24.22 ? 233 ILE A N 1 ATOM 1808 C CA . ILE A 1 237 ? 21.321 8.943 50.700 1.00 23.21 ? 233 ILE A CA 1 ATOM 1809 C C . ILE A 1 237 ? 21.393 9.540 49.287 1.00 23.03 ? 233 ILE A C 1 ATOM 1810 O O . ILE A 1 237 ? 20.339 9.798 48.682 1.00 22.48 ? 233 ILE A O 1 ATOM 1811 C CB . ILE A 1 237 ? 21.850 9.950 51.703 1.00 23.52 ? 233 ILE A CB 1 ATOM 1812 C CG1 . ILE A 1 237 ? 21.641 9.437 53.166 1.00 25.83 ? 233 ILE A CG1 1 ATOM 1813 C CG2 . ILE A 1 237 ? 21.151 11.311 51.509 1.00 23.28 ? 233 ILE A CG2 1 ATOM 1814 C CD1 . ILE A 1 237 ? 22.391 10.267 54.186 1.00 25.82 ? 233 ILE A CD1 1 ATOM 1815 N N . HIS A 1 238 ? 22.616 9.723 48.792 1.00 21.92 ? 234 HIS A N 1 ATOM 1816 C CA . HIS A 1 238 ? 22.843 10.590 47.604 1.00 21.04 ? 234 HIS A CA 1 ATOM 1817 C C . HIS A 1 238 ? 22.767 9.889 46.265 1.00 21.87 ? 234 HIS A C 1 ATOM 1818 O O . HIS A 1 238 ? 22.419 10.496 45.243 1.00 20.04 ? 234 HIS A O 1 ATOM 1819 C CB . HIS A 1 238 ? 24.103 11.366 47.807 1.00 19.82 ? 234 HIS A CB 1 ATOM 1820 C CG . HIS A 1 238 ? 23.980 12.372 48.886 1.00 22.93 ? 234 HIS A CG 1 ATOM 1821 N ND1 . HIS A 1 238 ? 24.571 12.237 50.128 1.00 24.46 ? 234 HIS A ND1 1 ATOM 1822 C CD2 . HIS A 1 238 ? 23.240 13.500 48.943 1.00 18.49 ? 234 HIS A CD2 1 ATOM 1823 C CE1 . HIS A 1 238 ? 24.255 13.277 50.886 1.00 20.59 ? 234 HIS A CE1 1 ATOM 1824 N NE2 . HIS A 1 238 ? 23.447 14.066 50.179 1.00 27.95 ? 234 HIS A NE2 1 ATOM 1825 N N . MET A 1 239 ? 23.015 8.578 46.269 1.00 20.48 ? 235 MET A N 1 ATOM 1826 C CA . MET A 1 239 ? 23.043 7.749 45.081 1.00 20.64 ? 235 MET A CA 1 ATOM 1827 C C . MET A 1 239 ? 21.760 7.083 44.611 1.00 21.16 ? 235 MET A C 1 ATOM 1828 O O . MET A 1 239 ? 21.558 6.887 43.405 1.00 21.39 ? 235 MET A O 1 ATOM 1829 C CB . MET A 1 239 ? 24.185 6.688 45.256 1.00 20.50 ? 235 MET A CB 1 ATOM 1830 C CG . MET A 1 239 ? 24.498 5.905 44.001 1.00 19.70 ? 235 MET A CG 1 ATOM 1831 S SD . MET A 1 239 ? 25.290 6.991 42.734 1.00 22.83 ? 235 MET A SD 1 ATOM 1832 C CE . MET A 1 239 ? 26.910 7.133 43.430 1.00 19.61 ? 235 MET A CE 1 ATOM 1833 N N . PRO A 1 240 ? 20.862 6.644 45.540 1.00 20.47 ? 236 PRO A N 1 ATOM 1834 C CA . PRO A 1 240 ? 19.815 5.785 45.085 1.00 20.35 ? 236 PRO A CA 1 ATOM 1835 C C . PRO A 1 240 ? 18.985 6.249 43.864 1.00 19.25 ? 236 PRO A C 1 ATOM 1836 O O . PRO A 1 240 ? 18.650 5.469 43.006 1.00 19.61 ? 236 PRO A O 1 ATOM 1837 C CB . PRO A 1 240 ? 18.912 5.686 46.330 1.00 23.08 ? 236 PRO A CB 1 ATOM 1838 C CG . PRO A 1 240 ? 19.900 5.668 47.404 1.00 21.15 ? 236 PRO A CG 1 ATOM 1839 C CD . PRO A 1 240 ? 20.883 6.715 47.022 1.00 22.00 ? 236 PRO A CD 1 ATOM 1840 N N . ALA A 1 241 ? 18.638 7.540 43.826 1.00 19.92 ? 237 ALA A N 1 ATOM 1841 C CA . ALA A 1 241 ? 17.826 7.984 42.726 1.00 19.68 ? 237 ALA A CA 1 ATOM 1842 C C . ALA A 1 241 ? 18.555 7.934 41.356 1.00 19.23 ? 237 ALA A C 1 ATOM 1843 O O . ALA A 1 241 ? 17.882 7.867 40.329 1.00 19.41 ? 237 ALA A O 1 ATOM 1844 C CB . ALA A 1 241 ? 17.260 9.417 42.988 1.00 18.76 ? 237 ALA A CB 1 ATOM 1845 N N . TYR A 1 242 ? 19.897 7.940 41.370 1.00 17.91 ? 238 TYR A N 1 ATOM 1846 C CA . TYR A 1 242 ? 20.617 7.673 40.090 1.00 18.10 ? 238 TYR A CA 1 ATOM 1847 C C . TYR A 1 242 ? 20.312 6.282 39.531 1.00 18.51 ? 238 TYR A C 1 ATOM 1848 O O . TYR A 1 242 ? 20.206 6.085 38.334 1.00 17.74 ? 238 TYR A O 1 ATOM 1849 C CB . TYR A 1 242 ? 22.151 7.951 40.169 1.00 17.16 ? 238 TYR A CB 1 ATOM 1850 C CG . TYR A 1 242 ? 22.441 9.424 40.211 1.00 17.58 ? 238 TYR A CG 1 ATOM 1851 C CD1 . TYR A 1 242 ? 22.552 10.142 39.005 1.00 17.53 ? 238 TYR A CD1 1 ATOM 1852 C CD2 . TYR A 1 242 ? 22.519 10.117 41.409 1.00 16.70 ? 238 TYR A CD2 1 ATOM 1853 C CE1 . TYR A 1 242 ? 22.755 11.519 39.006 1.00 17.51 ? 238 TYR A CE1 1 ATOM 1854 C CE2 . TYR A 1 242 ? 22.728 11.514 41.436 1.00 16.00 ? 238 TYR A CE2 1 ATOM 1855 C CZ . TYR A 1 242 ? 22.842 12.190 40.220 1.00 16.24 ? 238 TYR A CZ 1 ATOM 1856 O OH . TYR A 1 242 ? 23.008 13.531 40.310 1.00 16.22 ? 238 TYR A OH 1 ATOM 1857 N N . LYS A 1 243 ? 20.169 5.281 40.414 1.00 20.10 ? 239 LYS A N 1 ATOM 1858 C CA . LYS A 1 243 ? 19.777 3.998 39.902 1.00 20.35 ? 239 LYS A CA 1 ATOM 1859 C C . LYS A 1 243 ? 18.366 3.957 39.287 1.00 19.38 ? 239 LYS A C 1 ATOM 1860 O O . LYS A 1 243 ? 18.125 3.371 38.236 1.00 20.53 ? 239 LYS A O 1 ATOM 1861 C CB . LYS A 1 243 ? 19.917 2.942 41.028 1.00 21.72 ? 239 LYS A CB 1 ATOM 1862 C CG . LYS A 1 243 ? 19.566 1.545 40.547 1.00 26.14 ? 239 LYS A CG 1 ATOM 1863 C CD . LYS A 1 243 ? 20.649 0.908 39.606 1.00 35.77 ? 239 LYS A CD 1 ATOM 1864 C CE . LYS A 1 243 ? 20.258 -0.498 39.159 1.00 40.86 ? 239 LYS A CE 1 ATOM 1865 N NZ . LYS A 1 243 ? 18.781 -0.667 39.077 1.00 44.15 ? 239 LYS A NZ 1 ATOM 1866 N N . ASN A 1 244 ? 17.389 4.606 39.951 1.00 20.00 ? 240 ASN A N 1 ATOM 1867 C CA . ASN A 1 244 ? 16.084 4.732 39.358 1.00 18.38 ? 240 ASN A CA 1 ATOM 1868 C C . ASN A 1 244 ? 16.186 5.457 38.001 1.00 17.45 ? 240 ASN A C 1 ATOM 1869 O O . ASN A 1 244 ? 15.518 5.094 37.063 1.00 18.40 ? 240 ASN A O 1 ATOM 1870 C CB . ASN A 1 244 ? 15.160 5.552 40.283 1.00 20.07 ? 240 ASN A CB 1 ATOM 1871 C CG . ASN A 1 244 ? 14.953 4.873 41.664 1.00 20.04 ? 240 ASN A CG 1 ATOM 1872 O OD1 . ASN A 1 244 ? 15.758 4.998 42.542 1.00 23.78 ? 240 ASN A OD1 1 ATOM 1873 N ND2 . ASN A 1 244 ? 13.813 4.235 41.830 1.00 33.51 ? 240 ASN A ND2 1 ATOM 1874 N N . ALA A 1 245 ? 17.053 6.469 37.916 1.00 18.77 ? 241 ALA A N 1 ATOM 1875 C CA . ALA A 1 245 ? 17.229 7.157 36.636 1.00 19.23 ? 241 ALA A CA 1 ATOM 1876 C C . ALA A 1 245 ? 17.768 6.215 35.518 1.00 18.09 ? 241 ALA A C 1 ATOM 1877 O O . ALA A 1 245 ? 17.283 6.250 34.384 1.00 18.01 ? 241 ALA A O 1 ATOM 1878 C CB . ALA A 1 245 ? 18.149 8.359 36.823 1.00 18.35 ? 241 ALA A CB 1 ATOM 1879 N N . MET A 1 246 ? 18.744 5.373 35.862 1.00 18.74 ? 242 MET A N 1 ATOM 1880 C CA . MET A 1 246 ? 19.201 4.329 34.910 1.00 19.62 ? 242 MET A CA 1 ATOM 1881 C C . MET A 1 246 ? 18.068 3.413 34.488 1.00 18.85 ? 242 MET A C 1 ATOM 1882 O O . MET A 1 246 ? 17.875 3.098 33.311 1.00 18.92 ? 242 MET A O 1 ATOM 1883 C CB . MET A 1 246 ? 20.280 3.445 35.569 1.00 20.04 ? 242 MET A CB 1 ATOM 1884 C CG . MET A 1 246 ? 21.482 4.081 36.173 1.00 19.04 ? 242 MET A CG 1 ATOM 1885 S SD . MET A 1 246 ? 22.539 4.897 34.906 1.00 22.03 ? 242 MET A SD 1 ATOM 1886 C CE . MET A 1 246 ? 22.018 6.635 35.152 1.00 21.64 ? 242 MET A CE 1 ATOM 1887 N N . ASP A 1 247 ? 17.254 3.000 35.479 1.00 20.28 ? 243 ASP A N 1 ATOM 1888 C CA . ASP A 1 247 ? 16.139 2.123 35.161 1.00 20.65 ? 243 ASP A CA 1 ATOM 1889 C C . ASP A 1 247 ? 15.138 2.736 34.203 1.00 19.93 ? 243 ASP A C 1 ATOM 1890 O O . ASP A 1 247 ? 14.459 2.029 33.455 1.00 21.66 ? 243 ASP A O 1 ATOM 1891 C CB . ASP A 1 247 ? 15.396 1.725 36.458 1.00 20.95 ? 243 ASP A CB 1 ATOM 1892 C CG . ASP A 1 247 ? 16.176 0.768 37.326 1.00 26.08 ? 243 ASP A CG 1 ATOM 1893 O OD1 . ASP A 1 247 ? 17.218 0.219 36.882 1.00 25.26 ? 243 ASP A OD1 1 ATOM 1894 O OD2 . ASP A 1 247 ? 15.765 0.587 38.495 1.00 27.55 ? 243 ASP A OD2 1 ATOM 1895 N N . LYS A 1 248 ? 15.033 4.082 34.236 1.00 18.53 ? 244 LYS A N 1 ATOM 1896 C CA . LYS A 1 248 ? 14.126 4.831 33.370 1.00 19.74 ? 244 LYS A CA 1 ATOM 1897 C C . LYS A 1 248 ? 14.811 5.415 32.126 1.00 19.69 ? 244 LYS A C 1 ATOM 1898 O O . LYS A 1 248 ? 14.188 6.137 31.343 1.00 20.78 ? 244 LYS A O 1 ATOM 1899 C CB . LYS A 1 248 ? 13.425 5.908 34.228 1.00 18.97 ? 244 LYS A CB 1 ATOM 1900 C CG . LYS A 1 248 ? 12.586 5.250 35.324 1.00 20.50 ? 244 LYS A CG 1 ATOM 1901 C CD . LYS A 1 248 ? 12.101 6.271 36.377 1.00 22.28 ? 244 LYS A CD 1 ATOM 1902 C CE . LYS A 1 248 ? 11.489 5.484 37.566 1.00 22.88 ? 244 LYS A CE 1 ATOM 1903 N NZ . LYS A 1 248 ? 10.730 6.332 38.510 1.00 24.96 ? 244 LYS A NZ 1 ATOM 1904 N N . GLY A 1 249 ? 16.062 5.012 31.907 1.00 18.31 ? 245 GLY A N 1 ATOM 1905 C CA . GLY A 1 249 ? 16.702 5.297 30.610 1.00 18.93 ? 245 GLY A CA 1 ATOM 1906 C C . GLY A 1 249 ? 17.136 6.754 30.496 1.00 16.31 ? 245 GLY A C 1 ATOM 1907 O O . GLY A 1 249 ? 17.127 7.277 29.385 1.00 15.77 ? 245 GLY A O 1 ATOM 1908 N N . VAL A 1 250 ? 17.496 7.399 31.607 1.00 17.59 ? 246 VAL A N 1 ATOM 1909 C CA . VAL A 1 250 ? 17.897 8.832 31.508 1.00 16.12 ? 246 VAL A CA 1 ATOM 1910 C C . VAL A 1 250 ? 19.029 8.926 30.469 1.00 17.14 ? 246 VAL A C 1 ATOM 1911 O O . VAL A 1 250 ? 19.948 8.082 30.485 1.00 17.79 ? 246 VAL A O 1 ATOM 1912 C CB . VAL A 1 250 ? 18.276 9.414 32.850 1.00 16.74 ? 246 VAL A CB 1 ATOM 1913 C CG1 . VAL A 1 250 ? 19.635 8.822 33.379 1.00 17.44 ? 246 VAL A CG1 1 ATOM 1914 C CG2 . VAL A 1 250 ? 18.262 10.987 32.799 1.00 16.17 ? 246 VAL A CG2 1 ATOM 1915 N N . SER A 1 251 ? 18.970 9.933 29.598 1.00 14.39 ? 247 SER A N 1 ATOM 1916 C CA . SER A 1 251 ? 19.924 9.948 28.461 1.00 15.30 ? 247 SER A CA 1 ATOM 1917 C C . SER A 1 251 ? 21.287 10.442 28.837 1.00 15.05 ? 247 SER A C 1 ATOM 1918 O O . SER A 1 251 ? 22.289 10.069 28.167 1.00 15.80 ? 247 SER A O 1 ATOM 1919 C CB . SER A 1 251 ? 19.390 10.811 27.309 1.00 15.83 ? 247 SER A CB 1 ATOM 1920 O OG . SER A 1 251 ? 18.289 10.121 26.708 1.00 16.47 ? 247 SER A OG 1 ATOM 1921 N N . THR A 1 252 ? 21.353 11.357 29.815 1.00 14.14 ? 248 THR A N 1 ATOM 1922 C CA . THR A 1 252 ? 22.613 12.005 30.202 1.00 14.74 ? 248 THR A CA 1 ATOM 1923 C C . THR A 1 252 ? 22.662 12.185 31.687 1.00 15.84 ? 248 THR A C 1 ATOM 1924 O O . THR A 1 252 ? 21.620 12.166 32.386 1.00 14.33 ? 248 THR A O 1 ATOM 1925 C CB . THR A 1 252 ? 22.799 13.442 29.511 1.00 13.96 ? 248 THR A CB 1 ATOM 1926 O OG1 . THR A 1 252 ? 21.915 14.432 30.119 1.00 14.34 ? 248 THR A OG1 1 ATOM 1927 C CG2 . THR A 1 252 ? 22.482 13.363 28.041 1.00 14.82 ? 248 THR A CG2 1 ATOM 1928 N N . VAL A 1 253 ? 23.878 12.376 32.206 1.00 14.12 ? 249 VAL A N 1 ATOM 1929 C CA . VAL A 1 253 ? 24.133 12.680 33.607 1.00 14.65 ? 249 VAL A CA 1 ATOM 1930 C C . VAL A 1 253 ? 25.113 13.853 33.670 1.00 15.66 ? 249 VAL A C 1 ATOM 1931 O O . VAL A 1 253 ? 26.166 13.814 32.985 1.00 15.94 ? 249 VAL A O 1 ATOM 1932 C CB . VAL A 1 253 ? 24.755 11.462 34.379 1.00 14.36 ? 249 VAL A CB 1 ATOM 1933 C CG1 . VAL A 1 253 ? 25.166 11.896 35.810 1.00 14.63 ? 249 VAL A CG1 1 ATOM 1934 C CG2 . VAL A 1 253 ? 23.715 10.290 34.414 1.00 15.71 ? 249 VAL A CG2 1 ATOM 1935 N N . MET A 1 254 ? 24.829 14.880 34.463 1.00 14.50 ? 250 MET A N 1 ATOM 1936 C CA . MET A 1 254 ? 25.696 16.012 34.615 1.00 15.35 ? 250 MET A CA 1 ATOM 1937 C C . MET A 1 254 ? 26.450 15.875 35.932 1.00 15.84 ? 250 MET A C 1 ATOM 1938 O O . MET A 1 254 ? 25.844 15.601 36.975 1.00 16.05 ? 250 MET A O 1 ATOM 1939 C CB . MET A 1 254 ? 24.905 17.323 34.596 1.00 14.56 ? 250 MET A CB 1 ATOM 1940 C CG . MET A 1 254 ? 25.840 18.542 34.771 1.00 14.89 ? 250 MET A CG 1 ATOM 1941 S SD . MET A 1 254 ? 24.920 20.105 34.807 1.00 16.04 ? 250 MET A SD 1 ATOM 1942 C CE . MET A 1 254 ? 23.986 20.069 33.257 1.00 15.42 ? 250 MET A CE 1 ATOM 1943 N N . ILE A 1 255 ? 27.757 16.083 35.881 1.00 14.17 ? 251 ILE A N 1 ATOM 1944 C CA . ILE A 1 255 ? 28.573 16.024 37.080 1.00 15.61 ? 251 ILE A CA 1 ATOM 1945 C C . ILE A 1 255 ? 28.475 17.276 37.946 1.00 15.56 ? 251 ILE A C 1 ATOM 1946 O O . ILE A 1 255 ? 28.344 18.431 37.467 1.00 16.62 ? 251 ILE A O 1 ATOM 1947 C CB . ILE A 1 255 ? 30.049 15.766 36.620 1.00 15.69 ? 251 ILE A CB 1 ATOM 1948 C CG1 . ILE A 1 255 ? 30.112 14.536 35.731 1.00 15.77 ? 251 ILE A CG1 1 ATOM 1949 C CG2 . ILE A 1 255 ? 30.991 15.570 37.864 1.00 16.43 ? 251 ILE A CG2 1 ATOM 1950 C CD1 . ILE A 1 255 ? 29.587 13.213 36.310 1.00 19.50 ? 251 ILE A CD1 1 ATOM 1951 N N . SER A 1 256 ? 28.621 17.083 39.269 1.00 15.84 ? 252 SER A N 1 ATOM 1952 C CA . SER A 1 256 ? 28.538 18.146 40.232 1.00 16.20 ? 252 SER A CA 1 ATOM 1953 C C . SER A 1 256 ? 29.838 18.932 40.418 1.00 17.80 ? 252 SER A C 1 ATOM 1954 O O . SER A 1 256 ? 30.956 18.361 40.339 1.00 18.91 ? 252 SER A O 1 ATOM 1955 C CB . SER A 1 256 ? 28.160 17.519 41.584 1.00 15.77 ? 252 SER A CB 1 ATOM 1956 O OG . SER A 1 256 ? 27.915 18.558 42.518 1.00 16.62 ? 252 SER A OG 1 ATOM 1957 N N . TYR A 1 257 ? 29.716 20.214 40.675 1.00 16.84 ? 253 TYR A N 1 ATOM 1958 C CA . TYR A 1 257 ? 30.843 21.032 41.102 1.00 16.60 ? 253 TYR A CA 1 ATOM 1959 C C . TYR A 1 257 ? 31.389 20.565 42.452 1.00 18.11 ? 253 TYR A C 1 ATOM 1960 O O . TYR A 1 257 ? 32.562 20.819 42.765 1.00 18.94 ? 253 TYR A O 1 ATOM 1961 C CB . TYR A 1 257 ? 30.417 22.463 41.306 1.00 16.92 ? 253 TYR A CB 1 ATOM 1962 C CG . TYR A 1 257 ? 30.033 23.264 40.092 1.00 17.81 ? 253 TYR A CG 1 ATOM 1963 C CD1 . TYR A 1 257 ? 30.939 23.543 39.069 1.00 17.61 ? 253 TYR A CD1 1 ATOM 1964 C CD2 . TYR A 1 257 ? 28.747 23.822 40.014 1.00 16.55 ? 253 TYR A CD2 1 ATOM 1965 C CE1 . TYR A 1 257 ? 30.581 24.380 37.988 1.00 17.11 ? 253 TYR A CE1 1 ATOM 1966 C CE2 . TYR A 1 257 ? 28.374 24.667 38.958 1.00 16.98 ? 253 TYR A CE2 1 ATOM 1967 C CZ . TYR A 1 257 ? 29.279 24.897 37.926 1.00 18.25 ? 253 TYR A CZ 1 ATOM 1968 O OH . TYR A 1 257 ? 28.946 25.737 36.893 1.00 18.07 ? 253 TYR A OH 1 ATOM 1969 N N . SER A 1 258 ? 30.558 19.892 43.224 1.00 18.04 ? 254 SER A N 1 ATOM 1970 C CA . SER A 1 258 ? 30.916 19.532 44.632 1.00 19.28 ? 254 SER A CA 1 ATOM 1971 C C . SER A 1 258 ? 32.029 18.497 44.648 1.00 21.00 ? 254 SER A C 1 ATOM 1972 O O . SER A 1 258 ? 32.427 17.926 43.608 1.00 19.03 ? 254 SER A O 1 ATOM 1973 C CB . SER A 1 258 ? 29.652 19.013 45.393 1.00 18.34 ? 254 SER A CB 1 ATOM 1974 O OG . SER A 1 258 ? 29.022 17.930 44.780 1.00 19.56 ? 254 SER A OG 1 ATOM 1975 N N . SER A 1 259 ? 32.571 18.297 45.848 1.00 21.39 ? 255 SER A N 1 ATOM 1976 C CA . SER A 1 259 ? 33.565 17.233 46.063 1.00 22.20 ? 255 SER A CA 1 ATOM 1977 C C . SER A 1 259 ? 33.033 16.167 46.996 1.00 23.04 ? 255 SER A C 1 ATOM 1978 O O . SER A 1 259 ? 32.015 16.388 47.691 1.00 22.38 ? 255 SER A O 1 ATOM 1979 C CB . SER A 1 259 ? 34.834 17.844 46.663 1.00 20.91 ? 255 SER A CB 1 ATOM 1980 O OG . SER A 1 259 ? 35.456 18.765 45.798 1.00 22.01 ? 255 SER A OG 1 ATOM 1981 N N . TRP A 1 260 ? 33.664 14.988 46.998 1.00 22.20 ? 256 TRP A N 1 ATOM 1982 C CA . TRP A 1 260 ? 33.261 13.971 47.956 1.00 23.16 ? 256 TRP A CA 1 ATOM 1983 C C . TRP A 1 260 ? 34.501 13.573 48.742 1.00 25.12 ? 256 TRP A C 1 ATOM 1984 O O . TRP A 1 260 ? 35.451 13.038 48.134 1.00 25.28 ? 256 TRP A O 1 ATOM 1985 C CB . TRP A 1 260 ? 32.678 12.749 47.286 1.00 23.53 ? 256 TRP A CB 1 ATOM 1986 C CG . TRP A 1 260 ? 32.376 11.638 48.250 1.00 26.25 ? 256 TRP A CG 1 ATOM 1987 C CD1 . TRP A 1 260 ? 31.678 11.730 49.438 1.00 23.78 ? 256 TRP A CD1 1 ATOM 1988 C CD2 . TRP A 1 260 ? 32.761 10.263 48.116 1.00 27.04 ? 256 TRP A CD2 1 ATOM 1989 N NE1 . TRP A 1 260 ? 31.598 10.495 50.030 1.00 26.55 ? 256 TRP A NE1 1 ATOM 1990 C CE2 . TRP A 1 260 ? 32.264 9.578 49.253 1.00 28.11 ? 256 TRP A CE2 1 ATOM 1991 C CE3 . TRP A 1 260 ? 33.484 9.546 47.153 1.00 27.40 ? 256 TRP A CE3 1 ATOM 1992 C CZ2 . TRP A 1 260 ? 32.462 8.194 49.449 1.00 28.32 ? 256 TRP A CZ2 1 ATOM 1993 C CZ3 . TRP A 1 260 ? 33.670 8.164 47.337 1.00 28.79 ? 256 TRP A CZ3 1 ATOM 1994 C CH2 . TRP A 1 260 ? 33.163 7.506 48.482 1.00 29.18 ? 256 TRP A CH2 1 ATOM 1995 N N . ASN A 1 261 ? 34.474 13.846 50.047 1.00 24.89 ? 257 ASN A N 1 ATOM 1996 C CA . ASN A 1 261 ? 35.663 13.578 50.904 1.00 26.02 ? 257 ASN A CA 1 ATOM 1997 C C . ASN A 1 261 ? 36.906 14.213 50.303 1.00 26.83 ? 257 ASN A C 1 ATOM 1998 O O . ASN A 1 261 ? 38.008 13.610 50.296 1.00 27.32 ? 257 ASN A O 1 ATOM 1999 C CB . ASN A 1 261 ? 35.791 12.068 51.169 1.00 26.13 ? 257 ASN A CB 1 ATOM 2000 C CG . ASN A 1 261 ? 34.637 11.521 52.014 1.00 24.04 ? 257 ASN A CG 1 ATOM 2001 O OD1 . ASN A 1 261 ? 34.108 12.244 52.871 1.00 27.36 ? 257 ASN A OD1 1 ATOM 2002 N ND2 . ASN A 1 261 ? 34.243 10.275 51.782 1.00 25.41 ? 257 ASN A ND2 1 ATOM 2003 N N . GLY A 1 262 ? 36.749 15.440 49.812 1.00 25.47 ? 258 GLY A N 1 ATOM 2004 C CA . GLY A 1 262 ? 37.820 16.233 49.264 1.00 24.56 ? 258 GLY A CA 1 ATOM 2005 C C . GLY A 1 262 ? 38.224 15.967 47.806 1.00 24.56 ? 258 GLY A C 1 ATOM 2006 O O . GLY A 1 262 ? 39.117 16.655 47.333 1.00 26.90 ? 258 GLY A O 1 ATOM 2007 N N . VAL A 1 263 ? 37.602 15.000 47.124 1.00 24.78 ? 259 VAL A N 1 ATOM 2008 C CA . VAL A 1 263 ? 37.933 14.780 45.697 1.00 23.35 ? 259 VAL A CA 1 ATOM 2009 C C . VAL A 1 263 ? 36.887 15.471 44.828 1.00 23.14 ? 259 VAL A C 1 ATOM 2010 O O . VAL A 1 263 ? 35.708 15.169 44.994 1.00 23.77 ? 259 VAL A O 1 ATOM 2011 C CB . VAL A 1 263 ? 37.936 13.313 45.354 1.00 24.10 ? 259 VAL A CB 1 ATOM 2012 C CG1 . VAL A 1 263 ? 38.353 13.101 43.908 1.00 23.68 ? 259 VAL A CG1 1 ATOM 2013 C CG2 . VAL A 1 263 ? 38.977 12.572 46.297 1.00 25.77 ? 259 VAL A CG2 1 ATOM 2014 N N . LYS A 1 264 ? 37.340 16.363 43.954 1.00 21.71 ? 260 LYS A N 1 ATOM 2015 C CA . LYS A 1 264 ? 36.388 17.001 42.983 1.00 21.01 ? 260 LYS A CA 1 ATOM 2016 C C . LYS A 1 264 ? 35.619 15.948 42.205 1.00 20.94 ? 260 LYS A C 1 ATOM 2017 O O . LYS A 1 264 ? 36.193 15.015 41.630 1.00 21.29 ? 260 LYS A O 1 ATOM 2018 C CB . LYS A 1 264 ? 37.147 17.909 42.037 1.00 20.63 ? 260 LYS A CB 1 ATOM 2019 C CG . LYS A 1 264 ? 37.768 19.127 42.644 1.00 20.93 ? 260 LYS A CG 1 ATOM 2020 C CD . LYS A 1 264 ? 36.702 20.248 42.826 1.00 20.00 ? 260 LYS A CD 1 ATOM 2021 C CE . LYS A 1 264 ? 37.258 21.424 43.568 1.00 21.42 ? 260 LYS A CE 1 ATOM 2022 N NZ . LYS A 1 264 ? 36.243 22.480 43.703 1.00 23.74 ? 260 LYS A NZ 1 ATOM 2023 N N . MET A 1 265 ? 34.279 16.084 42.110 1.00 18.90 ? 261 MET A N 1 ATOM 2024 C CA . MET A 1 265 ? 33.568 15.127 41.321 1.00 17.77 ? 261 MET A CA 1 ATOM 2025 C C . MET A 1 265 ? 34.023 15.118 39.845 1.00 17.69 ? 261 MET A C 1 ATOM 2026 O O . MET A 1 265 ? 33.992 14.073 39.222 1.00 18.61 ? 261 MET A O 1 ATOM 2027 C CB . MET A 1 265 ? 32.024 15.427 41.363 1.00 18.69 ? 261 MET A CB 1 ATOM 2028 C CG . MET A 1 265 ? 31.339 14.932 42.654 1.00 18.71 ? 261 MET A CG 1 ATOM 2029 S SD . MET A 1 265 ? 31.450 13.153 42.997 1.00 22.28 ? 261 MET A SD 1 ATOM 2030 C CE . MET A 1 265 ? 31.308 12.369 41.379 1.00 21.30 ? 261 MET A CE 1 ATOM 2031 N N . HIS A 1 266 ? 34.336 16.292 39.316 1.00 19.47 ? 262 HIS A N 1 ATOM 2032 C CA . HIS A 1 266 ? 34.781 16.409 37.891 1.00 18.56 ? 262 HIS A CA 1 ATOM 2033 C C . HIS A 1 266 ? 36.143 15.719 37.634 1.00 21.05 ? 262 HIS A C 1 ATOM 2034 O O . HIS A 1 266 ? 36.537 15.583 36.478 1.00 19.65 ? 262 HIS A O 1 ATOM 2035 C CB . HIS A 1 266 ? 34.844 17.862 37.434 1.00 19.30 ? 262 HIS A CB 1 ATOM 2036 C CG . HIS A 1 266 ? 33.485 18.465 37.164 1.00 20.12 ? 262 HIS A CG 1 ATOM 2037 N ND1 . HIS A 1 266 ? 33.021 18.810 35.899 1.00 20.67 ? 262 HIS A ND1 1 ATOM 2038 C CD2 . HIS A 1 266 ? 32.506 18.795 38.040 1.00 16.01 ? 262 HIS A CD2 1 ATOM 2039 C CE1 . HIS A 1 266 ? 31.799 19.348 36.021 1.00 14.12 ? 262 HIS A CE1 1 ATOM 2040 N NE2 . HIS A 1 266 ? 31.454 19.310 37.298 1.00 20.63 ? 262 HIS A NE2 1 ATOM 2041 N N . ALA A 1 267 ? 36.822 15.282 38.714 1.00 20.74 ? 263 ALA A N 1 ATOM 2042 C CA . ALA A 1 267 ? 38.102 14.523 38.573 1.00 21.61 ? 263 ALA A CA 1 ATOM 2043 C C . ALA A 1 267 ? 37.996 13.124 39.160 1.00 23.64 ? 263 ALA A C 1 ATOM 2044 O O . ALA A 1 267 ? 39.020 12.403 39.276 1.00 24.07 ? 263 ALA A O 1 ATOM 2045 C CB . ALA A 1 267 ? 39.218 15.302 39.248 1.00 23.76 ? 263 ALA A CB 1 ATOM 2046 N N . ASN A 1 268 ? 36.802 12.692 39.508 1.00 21.36 ? 264 ASN A N 1 ATOM 2047 C CA . ASN A 1 268 ? 36.650 11.429 40.199 1.00 21.71 ? 264 ASN A CA 1 ATOM 2048 C C . ASN A 1 268 ? 36.418 10.248 39.293 1.00 22.13 ? 264 ASN A C 1 ATOM 2049 O O . ASN A 1 268 ? 35.299 9.872 38.950 1.00 21.76 ? 264 ASN A O 1 ATOM 2050 C CB . ASN A 1 268 ? 35.568 11.508 41.290 1.00 22.11 ? 264 ASN A CB 1 ATOM 2051 C CG . ASN A 1 268 ? 35.687 10.337 42.289 1.00 23.87 ? 264 ASN A CG 1 ATOM 2052 O OD1 . ASN A 1 268 ? 35.940 9.202 41.911 1.00 27.85 ? 264 ASN A OD1 1 ATOM 2053 N ND2 . ASN A 1 268 ? 35.438 10.628 43.562 1.00 27.45 ? 264 ASN A ND2 1 ATOM 2054 N N . GLN A 1 269 ? 37.515 9.599 38.890 1.00 22.33 ? 265 GLN A N 1 ATOM 2055 C CA . GLN A 1 269 ? 37.385 8.441 38.032 1.00 21.65 ? 265 GLN A CA 1 ATOM 2056 C C . GLN A 1 269 ? 36.678 7.252 38.670 1.00 21.74 ? 265 GLN A C 1 ATOM 2057 O O . GLN A 1 269 ? 35.938 6.545 38.006 1.00 22.08 ? 265 GLN A O 1 ATOM 2058 C CB . GLN A 1 269 ? 38.800 8.066 37.507 1.00 22.13 ? 265 GLN A CB 1 ATOM 2059 C CG . GLN A 1 269 ? 38.773 6.926 36.558 1.00 23.53 ? 265 GLN A CG 1 ATOM 2060 C CD . GLN A 1 269 ? 40.184 6.531 36.123 1.00 31.11 ? 265 GLN A CD 1 ATOM 2061 O OE1 . GLN A 1 269 ? 40.817 7.196 35.318 1.00 34.61 ? 265 GLN A OE1 1 ATOM 2062 N NE2 . GLN A 1 269 ? 40.681 5.444 36.701 1.00 35.49 ? 265 GLN A NE2 1 ATOM 2063 N N . ASP A 1 270 ? 36.931 7.015 39.972 1.00 23.11 ? 266 ASP A N 1 ATOM 2064 C CA . ASP A 1 270 ? 36.290 5.901 40.663 1.00 24.66 ? 266 ASP A CA 1 ATOM 2065 C C . ASP A 1 270 ? 34.765 5.998 40.606 1.00 22.38 ? 266 ASP A C 1 ATOM 2066 O O . ASP A 1 270 ? 34.095 5.026 40.341 1.00 23.30 ? 266 ASP A O 1 ATOM 2067 C CB . ASP A 1 270 ? 36.736 5.835 42.130 1.00 26.17 ? 266 ASP A CB 1 ATOM 2068 C CG . ASP A 1 270 ? 38.208 5.366 42.301 1.00 33.56 ? 266 ASP A CG 1 ATOM 2069 O OD1 . ASP A 1 270 ? 38.777 5.642 43.393 1.00 40.39 ? 266 ASP A OD1 1 ATOM 2070 O OD2 . ASP A 1 270 ? 38.798 4.741 41.378 1.00 37.64 ? 266 ASP A OD2 1 ATOM 2071 N N . LEU A 1 271 ? 34.227 7.207 40.808 1.00 23.01 ? 267 LEU A N 1 ATOM 2072 C CA . LEU A 1 271 ? 32.768 7.351 40.752 1.00 21.76 ? 267 LEU A CA 1 ATOM 2073 C C . LEU A 1 271 ? 32.163 7.495 39.350 1.00 19.43 ? 267 LEU A C 1 ATOM 2074 O O . LEU A 1 271 ? 31.133 6.881 39.067 1.00 20.57 ? 267 LEU A O 1 ATOM 2075 C CB . LEU A 1 271 ? 32.311 8.496 41.640 1.00 20.57 ? 267 LEU A CB 1 ATOM 2076 C CG . LEU A 1 271 ? 32.470 8.272 43.156 1.00 23.12 ? 267 LEU A CG 1 ATOM 2077 C CD1 . LEU A 1 271 ? 32.002 9.535 43.868 1.00 24.09 ? 267 LEU A CD1 1 ATOM 2078 C CD2 . LEU A 1 271 ? 31.685 7.020 43.611 1.00 24.69 ? 267 LEU A CD2 1 ATOM 2079 N N . VAL A 1 272 ? 32.797 8.273 38.485 1.00 20.83 ? 268 VAL A N 1 ATOM 2080 C CA . VAL A 1 272 ? 32.231 8.480 37.141 1.00 20.15 ? 268 VAL A CA 1 ATOM 2081 C C . VAL A 1 272 ? 32.400 7.263 36.248 1.00 20.31 ? 268 VAL A C 1 ATOM 2082 O O . VAL A 1 272 ? 31.471 6.790 35.602 1.00 20.72 ? 268 VAL A O 1 ATOM 2083 C CB . VAL A 1 272 ? 32.855 9.711 36.472 1.00 20.12 ? 268 VAL A CB 1 ATOM 2084 C CG1 . VAL A 1 272 ? 32.311 9.904 35.003 1.00 19.40 ? 268 VAL A CG1 1 ATOM 2085 C CG2 . VAL A 1 272 ? 32.622 10.961 37.314 1.00 20.24 ? 268 VAL A CG2 1 ATOM 2086 N N . THR A 1 273 ? 33.647 6.759 36.203 1.00 21.87 ? 269 THR A N 1 ATOM 2087 C CA . THR A 1 273 ? 33.913 5.540 35.451 1.00 22.32 ? 269 THR A CA 1 ATOM 2088 C C . THR A 1 273 ? 33.642 4.274 36.273 1.00 23.11 ? 269 THR A C 1 ATOM 2089 O O . THR A 1 273 ? 32.875 3.453 35.857 1.00 22.43 ? 269 THR A O 1 ATOM 2090 C CB . THR A 1 273 ? 35.343 5.554 34.839 1.00 23.11 ? 269 THR A CB 1 ATOM 2091 O OG1 . THR A 1 273 ? 35.430 6.666 33.943 1.00 24.98 ? 269 THR A OG1 1 ATOM 2092 C CG2 . THR A 1 273 ? 35.576 4.326 34.026 1.00 23.21 ? 269 THR A CG2 1 ATOM 2093 N N . GLY A 1 274 ? 34.258 4.153 37.445 1.00 24.56 ? 270 GLY A N 1 ATOM 2094 C CA . GLY A 1 274 ? 34.111 2.912 38.211 1.00 25.44 ? 270 GLY A CA 1 ATOM 2095 C C . GLY A 1 274 ? 32.688 2.574 38.597 1.00 25.46 ? 270 GLY A C 1 ATOM 2096 O O . GLY A 1 274 ? 32.271 1.419 38.523 1.00 27.54 ? 270 GLY A O 1 ATOM 2097 N N . TYR A 1 275 ? 31.936 3.596 39.010 1.00 24.28 ? 271 TYR A N 1 ATOM 2098 C CA . TYR A 1 275 ? 30.601 3.359 39.546 1.00 23.60 ? 271 TYR A CA 1 ATOM 2099 C C . TYR A 1 275 ? 29.521 3.638 38.501 1.00 21.50 ? 271 TYR A C 1 ATOM 2100 O O . TYR A 1 275 ? 28.799 2.752 38.088 1.00 22.35 ? 271 TYR A O 1 ATOM 2101 C CB . TYR A 1 275 ? 30.357 4.152 40.847 1.00 23.56 ? 271 TYR A CB 1 ATOM 2102 C CG . TYR A 1 275 ? 29.148 3.569 41.572 1.00 25.82 ? 271 TYR A CG 1 ATOM 2103 C CD1 . TYR A 1 275 ? 29.238 2.346 42.256 1.00 26.72 ? 271 TYR A CD1 1 ATOM 2104 C CD2 . TYR A 1 275 ? 27.898 4.195 41.522 1.00 26.43 ? 271 TYR A CD2 1 ATOM 2105 C CE1 . TYR A 1 275 ? 28.150 1.775 42.863 1.00 29.34 ? 271 TYR A CE1 1 ATOM 2106 C CE2 . TYR A 1 275 ? 26.776 3.627 42.146 1.00 27.39 ? 271 TYR A CE2 1 ATOM 2107 C CZ . TYR A 1 275 ? 26.905 2.409 42.817 1.00 31.07 ? 271 TYR A CZ 1 ATOM 2108 O OH . TYR A 1 275 ? 25.820 1.838 43.441 1.00 31.08 ? 271 TYR A OH 1 ATOM 2109 N N . LEU A 1 276 ? 29.429 4.883 38.031 1.00 20.77 ? 272 LEU A N 1 ATOM 2110 C CA . LEU A 1 276 ? 28.333 5.219 37.125 1.00 21.38 ? 272 LEU A CA 1 ATOM 2111 C C . LEU A 1 276 ? 28.366 4.427 35.835 1.00 20.68 ? 272 LEU A C 1 ATOM 2112 O O . LEU A 1 276 ? 27.389 3.777 35.444 1.00 20.33 ? 272 LEU A O 1 ATOM 2113 C CB . LEU A 1 276 ? 28.382 6.716 36.821 1.00 19.02 ? 272 LEU A CB 1 ATOM 2114 C CG . LEU A 1 276 ? 27.342 7.252 35.845 1.00 21.17 ? 272 LEU A CG 1 ATOM 2115 C CD1 . LEU A 1 276 ? 25.847 7.006 36.269 1.00 22.03 ? 272 LEU A CD1 1 ATOM 2116 C CD2 . LEU A 1 276 ? 27.604 8.740 35.599 1.00 20.23 ? 272 LEU A CD2 1 ATOM 2117 N N . LYS A 1 277 ? 29.509 4.460 35.134 1.00 21.42 ? 273 LYS A N 1 ATOM 2118 C CA . LYS A 1 277 ? 29.603 3.693 33.905 1.00 21.34 ? 273 LYS A CA 1 ATOM 2119 C C . LYS A 1 277 ? 29.736 2.157 34.104 1.00 22.29 ? 273 LYS A C 1 ATOM 2120 O O . LYS A 1 277 ? 28.992 1.409 33.519 1.00 23.23 ? 273 LYS A O 1 ATOM 2121 C CB . LYS A 1 277 ? 30.762 4.211 33.053 1.00 20.90 ? 273 LYS A CB 1 ATOM 2122 C CG . LYS A 1 277 ? 30.490 5.658 32.487 1.00 20.29 ? 273 LYS A CG 1 ATOM 2123 C CD . LYS A 1 277 ? 31.611 6.137 31.580 1.00 21.21 ? 273 LYS A CD 1 ATOM 2124 C CE . LYS A 1 277 ? 31.282 7.487 30.852 1.00 19.18 ? 273 LYS A CE 1 ATOM 2125 N NZ . LYS A 1 277 ? 32.375 7.736 29.843 1.00 21.27 ? 273 LYS A NZ 1 ATOM 2126 N N . ASP A 1 278 ? 30.678 1.746 34.942 1.00 24.97 ? 274 ASP A N 1 ATOM 2127 C CA . ASP A 1 278 ? 31.048 0.306 34.997 1.00 27.10 ? 274 ASP A CA 1 ATOM 2128 C C . ASP A 1 278 ? 30.168 -0.523 35.926 1.00 27.72 ? 274 ASP A C 1 ATOM 2129 O O . ASP A 1 278 ? 30.056 -1.748 35.727 1.00 29.38 ? 274 ASP A O 1 ATOM 2130 C CB . ASP A 1 278 ? 32.501 0.123 35.427 1.00 26.73 ? 274 ASP A CB 1 ATOM 2131 C CG . ASP A 1 278 ? 33.518 0.623 34.397 1.00 30.95 ? 274 ASP A CG 1 ATOM 2132 O OD1 . ASP A 1 278 ? 33.145 1.006 33.261 1.00 32.16 ? 274 ASP A OD1 1 ATOM 2133 O OD2 . ASP A 1 278 ? 34.722 0.636 34.767 1.00 33.79 ? 274 ASP A OD2 1 ATOM 2134 N N . THR A 1 279 ? 29.550 0.108 36.926 1.00 27.05 ? 275 THR A N 1 ATOM 2135 C CA . THR A 1 279 ? 28.698 -0.610 37.899 1.00 27.46 ? 275 THR A CA 1 ATOM 2136 C C . THR A 1 279 ? 27.217 -0.411 37.613 1.00 26.13 ? 275 THR A C 1 ATOM 2137 O O . THR A 1 279 ? 26.477 -1.376 37.527 1.00 26.94 ? 275 THR A O 1 ATOM 2138 C CB . THR A 1 279 ? 29.053 -0.224 39.344 1.00 27.48 ? 275 THR A CB 1 ATOM 2139 O OG1 . THR A 1 279 ? 30.447 -0.475 39.561 1.00 28.16 ? 275 THR A OG1 1 ATOM 2140 C CG2 . THR A 1 279 ? 28.227 -1.000 40.372 1.00 29.54 ? 275 THR A CG2 1 ATOM 2141 N N . LEU A 1 280 ? 26.782 0.840 37.392 1.00 25.29 ? 276 LEU A N 1 ATOM 2142 C CA . LEU A 1 280 ? 25.387 1.086 37.030 1.00 25.53 ? 276 LEU A CA 1 ATOM 2143 C C . LEU A 1 280 ? 25.135 0.851 35.537 1.00 24.50 ? 276 LEU A C 1 ATOM 2144 O O . LEU A 1 280 ? 23.986 0.839 35.083 1.00 25.68 ? 276 LEU A O 1 ATOM 2145 C CB . LEU A 1 280 ? 24.969 2.521 37.449 1.00 24.57 ? 276 LEU A CB 1 ATOM 2146 C CG . LEU A 1 280 ? 25.045 2.860 38.941 1.00 27.02 ? 276 LEU A CG 1 ATOM 2147 C CD1 . LEU A 1 280 ? 24.522 4.257 39.272 1.00 28.90 ? 276 LEU A CD1 1 ATOM 2148 C CD2 . LEU A 1 280 ? 24.295 1.777 39.758 1.00 28.56 ? 276 LEU A CD2 1 ATOM 2149 N N . LYS A 1 281 ? 26.204 0.617 34.755 1.00 24.58 ? 277 LYS A N 1 ATOM 2150 C CA . LYS A 1 281 ? 26.070 0.300 33.329 1.00 23.39 ? 277 LYS A CA 1 ATOM 2151 C C . LYS A 1 281 ? 25.450 1.485 32.550 1.00 21.51 ? 277 LYS A C 1 ATOM 2152 O O . LYS A 1 281 ? 24.752 1.281 31.565 1.00 22.27 ? 277 LYS A O 1 ATOM 2153 C CB . LYS A 1 281 ? 25.303 -0.988 33.034 1.00 24.55 ? 277 LYS A CB 1 ATOM 2154 C CG . LYS A 1 281 ? 25.850 -2.226 33.776 1.00 27.60 ? 277 LYS A CG 1 ATOM 2155 C CD . LYS A 1 281 ? 27.316 -2.496 33.426 1.00 30.76 ? 277 LYS A CD 1 ATOM 2156 C CE . LYS A 1 281 ? 27.861 -3.698 34.260 1.00 35.79 ? 277 LYS A CE 1 ATOM 2157 N NZ . LYS A 1 281 ? 29.356 -3.791 34.223 1.00 35.94 ? 277 LYS A NZ 1 ATOM 2158 N N . PHE A 1 282 ? 25.716 2.701 33.010 1.00 21.18 ? 278 PHE A N 1 ATOM 2159 C CA . PHE A 1 282 ? 25.192 3.873 32.272 1.00 19.62 ? 278 PHE A CA 1 ATOM 2160 C C . PHE A 1 282 ? 25.847 3.906 30.878 1.00 19.89 ? 278 PHE A C 1 ATOM 2161 O O . PHE A 1 282 ? 27.101 3.921 30.791 1.00 20.33 ? 278 PHE A O 1 ATOM 2162 C CB . PHE A 1 282 ? 25.509 5.145 33.035 1.00 19.01 ? 278 PHE A CB 1 ATOM 2163 C CG . PHE A 1 282 ? 25.032 6.404 32.323 1.00 18.81 ? 278 PHE A CG 1 ATOM 2164 C CD1 . PHE A 1 282 ? 23.686 6.543 31.909 1.00 19.04 ? 278 PHE A CD1 1 ATOM 2165 C CD2 . PHE A 1 282 ? 25.941 7.409 32.027 1.00 17.45 ? 278 PHE A CD2 1 ATOM 2166 C CE1 . PHE A 1 282 ? 23.246 7.717 31.276 1.00 18.13 ? 278 PHE A CE1 1 ATOM 2167 C CE2 . PHE A 1 282 ? 25.498 8.571 31.379 1.00 18.96 ? 278 PHE A CE2 1 ATOM 2168 C CZ . PHE A 1 282 ? 24.162 8.711 31.021 1.00 17.61 ? 278 PHE A CZ 1 ATOM 2169 N N . LYS A 1 283 ? 25.028 3.968 29.834 1.00 19.68 ? 279 LYS A N 1 ATOM 2170 C CA . LYS A 1 283 ? 25.503 3.967 28.446 1.00 19.72 ? 279 LYS A CA 1 ATOM 2171 C C . LYS A 1 283 ? 25.128 5.261 27.685 1.00 20.14 ? 279 LYS A C 1 ATOM 2172 O O . LYS A 1 283 ? 25.372 5.371 26.475 1.00 19.55 ? 279 LYS A O 1 ATOM 2173 C CB . LYS A 1 283 ? 24.951 2.779 27.671 1.00 20.60 ? 279 LYS A CB 1 ATOM 2174 C CG . LYS A 1 283 ? 25.303 1.431 28.247 1.00 24.76 ? 279 LYS A CG 1 ATOM 2175 C CD . LYS A 1 283 ? 26.795 1.175 28.237 1.00 29.09 ? 279 LYS A CD 1 ATOM 2176 C CE . LYS A 1 283 ? 27.087 -0.367 28.473 1.00 33.93 ? 279 LYS A CE 1 ATOM 2177 N NZ . LYS A 1 283 ? 28.539 -0.530 28.883 1.00 33.94 ? 279 LYS A NZ 1 ATOM 2178 N N . GLY A 1 284 ? 24.499 6.214 28.389 1.00 18.68 ? 280 GLY A N 1 ATOM 2179 C CA . GLY A 1 284 ? 24.324 7.553 27.815 1.00 18.74 ? 280 GLY A CA 1 ATOM 2180 C C . GLY A 1 284 ? 25.602 8.356 27.949 1.00 18.84 ? 280 GLY A C 1 ATOM 2181 O O . GLY A 1 284 ? 26.684 7.793 28.195 1.00 19.22 ? 280 GLY A O 1 ATOM 2182 N N . PHE A 1 285 ? 25.507 9.681 27.794 1.00 17.15 ? 281 PHE A N 1 ATOM 2183 C CA . PHE A 1 285 ? 26.675 10.535 27.939 1.00 16.21 ? 281 PHE A CA 1 ATOM 2184 C C . PHE A 1 285 ? 26.726 11.339 29.210 1.00 17.12 ? 281 PHE A C 1 ATOM 2185 O O . PHE A 1 285 ? 25.687 11.768 29.754 1.00 15.82 ? 281 PHE A O 1 ATOM 2186 C CB . PHE A 1 285 ? 27.024 11.358 26.688 1.00 15.96 ? 281 PHE A CB 1 ATOM 2187 C CG . PHE A 1 285 ? 26.122 12.561 26.386 1.00 14.95 ? 281 PHE A CG 1 ATOM 2188 C CD1 . PHE A 1 285 ? 26.286 13.763 27.056 1.00 14.13 ? 281 PHE A CD1 1 ATOM 2189 C CD2 . PHE A 1 285 ? 25.187 12.473 25.340 1.00 14.09 ? 281 PHE A CD2 1 ATOM 2190 C CE1 . PHE A 1 285 ? 25.484 14.915 26.688 1.00 14.65 ? 281 PHE A CE1 1 ATOM 2191 C CE2 . PHE A 1 285 ? 24.393 13.589 24.956 1.00 14.57 ? 281 PHE A CE2 1 ATOM 2192 C CZ . PHE A 1 285 ? 24.610 14.821 25.625 1.00 13.70 ? 281 PHE A CZ 1 ATOM 2193 N N . VAL A 1 286 ? 27.941 11.490 29.730 1.00 15.72 ? 282 VAL A N 1 ATOM 2194 C CA . VAL A 1 286 ? 28.223 12.257 30.929 1.00 16.20 ? 282 VAL A CA 1 ATOM 2195 C C . VAL A 1 286 ? 28.703 13.631 30.507 1.00 16.36 ? 282 VAL A C 1 ATOM 2196 O O . VAL A 1 286 ? 29.673 13.767 29.759 1.00 16.39 ? 282 VAL A O 1 ATOM 2197 C CB . VAL A 1 286 ? 29.338 11.551 31.762 1.00 16.14 ? 282 VAL A CB 1 ATOM 2198 C CG1 . VAL A 1 286 ? 29.730 12.410 32.956 1.00 18.09 ? 282 VAL A CG1 1 ATOM 2199 C CG2 . VAL A 1 286 ? 28.859 10.153 32.184 1.00 18.41 ? 282 VAL A CG2 1 ATOM 2200 N N . ILE A 1 287 ? 28.050 14.683 30.999 1.00 15.82 ? 283 ILE A N 1 ATOM 2201 C CA . ILE A 1 287 ? 28.396 16.047 30.650 1.00 15.00 ? 283 ILE A CA 1 ATOM 2202 C C . ILE A 1 287 ? 28.923 16.780 31.903 1.00 15.24 ? 283 ILE A C 1 ATOM 2203 O O . ILE A 1 287 ? 28.437 16.539 33.023 1.00 15.18 ? 283 ILE A O 1 ATOM 2204 C CB . ILE A 1 287 ? 27.123 16.779 30.032 1.00 13.98 ? 283 ILE A CB 1 ATOM 2205 C CG1 . ILE A 1 287 ? 27.469 18.175 29.535 1.00 14.11 ? 283 ILE A CG1 1 ATOM 2206 C CG2 . ILE A 1 287 ? 25.935 16.824 31.074 1.00 15.10 ? 283 ILE A CG2 1 ATOM 2207 C CD1 . ILE A 1 287 ? 26.402 18.839 28.651 1.00 16.04 ? 283 ILE A CD1 1 ATOM 2208 N N . SER A 1 288 ? 29.894 17.682 31.729 1.00 15.12 ? 284 SER A N 1 ATOM 2209 C CA . SER A 1 288 ? 30.350 18.531 32.819 1.00 14.38 ? 284 SER A CA 1 ATOM 2210 C C . SER A 1 288 ? 29.293 19.570 33.198 1.00 15.14 ? 284 SER A C 1 ATOM 2211 O O . SER A 1 288 ? 28.349 19.825 32.404 1.00 15.21 ? 284 SER A O 1 ATOM 2212 C CB . SER A 1 288 ? 31.649 19.285 32.430 1.00 16.14 ? 284 SER A CB 1 ATOM 2213 O OG . SER A 1 288 ? 31.419 20.456 31.656 1.00 15.58 ? 284 SER A OG 1 ATOM 2214 N N . ASP A 1 289 ? 29.444 20.168 34.357 1.00 14.67 ? 285 ASP A N 1 ATOM 2215 C CA . ASP A 1 289 ? 28.780 21.426 34.620 1.00 15.17 ? 285 ASP A CA 1 ATOM 2216 C C . ASP A 1 289 ? 29.503 22.590 33.972 1.00 15.83 ? 285 ASP A C 1 ATOM 2217 O O . ASP A 1 289 ? 30.583 22.395 33.338 1.00 15.72 ? 285 ASP A O 1 ATOM 2218 C CB . ASP A 1 289 ? 28.487 21.603 36.134 1.00 15.59 ? 285 ASP A CB 1 ATOM 2219 C CG . ASP A 1 289 ? 27.221 22.417 36.391 1.00 18.43 ? 285 ASP A CG 1 ATOM 2220 O OD1 . ASP A 1 289 ? 26.797 23.227 35.498 1.00 17.17 ? 285 ASP A OD1 1 ATOM 2221 O OD2 . ASP A 1 289 ? 26.656 22.261 37.483 1.00 18.23 ? 285 ASP A OD2 1 ATOM 2222 N N . TRP A 1 290 ? 28.987 23.790 34.167 1.00 14.44 ? 286 TRP A N 1 ATOM 2223 C CA . TRP A 1 290 ? 29.435 24.972 33.417 1.00 14.50 ? 286 TRP A CA 1 ATOM 2224 C C . TRP A 1 290 ? 30.790 25.422 33.984 1.00 16.10 ? 286 TRP A C 1 ATOM 2225 O O . TRP A 1 290 ? 30.864 25.863 35.121 1.00 16.22 ? 286 TRP A O 1 ATOM 2226 C CB . TRP A 1 290 ? 28.373 26.076 33.596 1.00 15.08 ? 286 TRP A CB 1 ATOM 2227 C CG . TRP A 1 290 ? 28.685 27.450 33.121 1.00 15.73 ? 286 TRP A CG 1 ATOM 2228 C CD1 . TRP A 1 290 ? 29.594 28.353 33.665 1.00 16.01 ? 286 TRP A CD1 1 ATOM 2229 C CD2 . TRP A 1 290 ? 27.979 28.161 32.110 1.00 14.25 ? 286 TRP A CD2 1 ATOM 2230 N NE1 . TRP A 1 290 ? 29.516 29.573 32.997 1.00 17.23 ? 286 TRP A NE1 1 ATOM 2231 C CE2 . TRP A 1 290 ? 28.525 29.479 32.043 1.00 16.78 ? 286 TRP A CE2 1 ATOM 2232 C CE3 . TRP A 1 290 ? 26.921 27.812 31.232 1.00 14.33 ? 286 TRP A CE3 1 ATOM 2233 C CZ2 . TRP A 1 290 ? 28.060 30.456 31.130 1.00 16.99 ? 286 TRP A CZ2 1 ATOM 2234 C CZ3 . TRP A 1 290 ? 26.463 28.792 30.322 1.00 14.58 ? 286 TRP A CZ3 1 ATOM 2235 C CH2 . TRP A 1 290 ? 27.011 30.095 30.300 1.00 15.72 ? 286 TRP A CH2 1 ATOM 2236 N N . GLU A 1 291 ? 31.830 25.340 33.142 1.00 15.98 ? 287 GLU A N 1 ATOM 2237 C CA . GLU A 1 291 ? 33.213 25.570 33.637 1.00 16.75 ? 287 GLU A CA 1 ATOM 2238 C C . GLU A 1 291 ? 33.494 24.632 34.804 1.00 17.39 ? 287 GLU A C 1 ATOM 2239 O O . GLU A 1 291 ? 34.334 24.958 35.679 1.00 17.23 ? 287 GLU A O 1 ATOM 2240 C CB . GLU A 1 291 ? 33.450 27.023 34.053 1.00 17.47 ? 287 GLU A CB 1 ATOM 2241 C CG . GLU A 1 291 ? 33.357 28.028 32.931 1.00 21.49 ? 287 GLU A CG 1 ATOM 2242 C CD . GLU A 1 291 ? 33.347 29.458 33.475 1.00 27.32 ? 287 GLU A CD 1 ATOM 2243 O OE1 . GLU A 1 291 ? 33.130 29.667 34.693 1.00 30.84 ? 287 GLU A OE1 1 ATOM 2244 O OE2 . GLU A 1 291 ? 33.452 30.372 32.661 1.00 32.17 ? 287 GLU A OE2 1 ATOM 2245 N N . GLY A 1 292 ? 32.831 23.484 34.837 1.00 16.01 ? 288 GLY A N 1 ATOM 2246 C CA . GLY A 1 292 ? 33.062 22.484 35.897 1.00 16.90 ? 288 GLY A CA 1 ATOM 2247 C C . GLY A 1 292 ? 34.506 21.987 35.931 1.00 18.58 ? 288 GLY A C 1 ATOM 2248 O O . GLY A 1 292 ? 35.076 21.803 37.028 1.00 18.48 ? 288 GLY A O 1 ATOM 2249 N N . ILE A 1 293 ? 35.096 21.802 34.754 1.00 17.76 ? 289 ILE A N 1 ATOM 2250 C CA . ILE A 1 293 ? 36.489 21.297 34.721 1.00 17.71 ? 289 ILE A CA 1 ATOM 2251 C C . ILE A 1 293 ? 37.446 22.370 35.207 1.00 19.78 ? 289 ILE A C 1 ATOM 2252 O O . ILE A 1 293 ? 38.435 22.022 35.908 1.00 20.18 ? 289 ILE A O 1 ATOM 2253 C CB . ILE A 1 293 ? 36.877 20.680 33.356 1.00 17.26 ? 289 ILE A CB 1 ATOM 2254 C CG1 . ILE A 1 293 ? 37.154 21.753 32.304 1.00 17.98 ? 289 ILE A CG1 1 ATOM 2255 C CG2 . ILE A 1 293 ? 35.791 19.663 32.945 1.00 19.50 ? 289 ILE A CG2 1 ATOM 2256 C CD1 . ILE A 1 293 ? 37.795 21.118 31.008 1.00 17.32 ? 289 ILE A CD1 1 ATOM 2257 N N . ASP A 1 294 ? 37.175 23.625 34.871 1.00 18.37 ? 290 ASP A N 1 ATOM 2258 C CA . ASP A 1 294 ? 37.983 24.812 35.322 1.00 18.96 ? 290 ASP A CA 1 ATOM 2259 C C . ASP A 1 294 ? 38.066 24.782 36.838 1.00 20.06 ? 290 ASP A C 1 ATOM 2260 O O . ASP A 1 294 ? 39.116 25.083 37.447 1.00 20.07 ? 290 ASP A O 1 ATOM 2261 C CB . ASP A 1 294 ? 37.341 26.157 34.924 1.00 19.06 ? 290 ASP A CB 1 ATOM 2262 C CG . ASP A 1 294 ? 37.012 26.248 33.426 1.00 20.68 ? 290 ASP A CG 1 ATOM 2263 O OD1 . ASP A 1 294 ? 36.397 25.293 32.908 1.00 21.51 ? 290 ASP A OD1 1 ATOM 2264 O OD2 . ASP A 1 294 ? 37.386 27.298 32.803 1.00 24.61 ? 290 ASP A OD2 1 ATOM 2265 N N . ARG A 1 295 ? 36.947 24.402 37.482 1.00 18.54 ? 291 ARG A N 1 ATOM 2266 C CA . ARG A 1 295 ? 36.837 24.526 38.940 1.00 19.88 ? 291 ARG A CA 1 ATOM 2267 C C . ARG A 1 295 ? 37.416 23.312 39.701 1.00 20.48 ? 291 ARG A C 1 ATOM 2268 O O . ARG A 1 295 ? 37.295 23.231 40.962 1.00 21.40 ? 291 ARG A O 1 ATOM 2269 C CB . ARG A 1 295 ? 35.344 24.822 39.309 1.00 18.64 ? 291 ARG A CB 1 ATOM 2270 C CG . ARG A 1 295 ? 34.914 26.170 38.744 1.00 20.61 ? 291 ARG A CG 1 ATOM 2271 C CD . ARG A 1 295 ? 33.422 26.522 39.063 1.00 21.99 ? 291 ARG A CD 1 ATOM 2272 N NE A ARG A 1 295 ? 32.903 27.572 38.179 0.60 19.88 ? 291 ARG A NE 1 ATOM 2273 N NE B ARG A 1 295 ? 33.312 27.472 40.172 0.40 28.32 ? 291 ARG A NE 1 ATOM 2274 C CZ A ARG A 1 295 ? 31.668 28.063 38.232 0.60 22.47 ? 291 ARG A CZ 1 ATOM 2275 C CZ B ARG A 1 295 ? 33.511 28.790 40.073 0.40 29.66 ? 291 ARG A CZ 1 ATOM 2276 N NH1 A ARG A 1 295 ? 31.285 28.951 37.326 0.60 21.46 ? 291 ARG A NH1 1 ATOM 2277 N NH1 B ARG A 1 295 ? 33.401 29.560 41.142 0.40 35.10 ? 291 ARG A NH1 1 ATOM 2278 N NH2 A ARG A 1 295 ? 30.801 27.660 39.174 0.60 22.21 ? 291 ARG A NH2 1 ATOM 2279 N NH2 B ARG A 1 295 ? 33.811 29.356 38.922 0.40 31.98 ? 291 ARG A NH2 1 ATOM 2280 N N . ILE A 1 296 ? 38.060 22.366 38.997 1.00 21.24 ? 292 ILE A N 1 ATOM 2281 C CA . ILE A 1 296 ? 38.814 21.259 39.623 1.00 22.50 ? 292 ILE A CA 1 ATOM 2282 C C . ILE A 1 296 ? 40.008 21.837 40.379 1.00 24.46 ? 292 ILE A C 1 ATOM 2283 O O . ILE A 1 296 ? 40.368 21.344 41.466 1.00 23.84 ? 292 ILE A O 1 ATOM 2284 C CB . ILE A 1 296 ? 39.327 20.293 38.577 1.00 21.92 ? 292 ILE A CB 1 ATOM 2285 C CG1 . ILE A 1 296 ? 38.187 19.444 38.017 1.00 19.79 ? 292 ILE A CG1 1 ATOM 2286 C CG2 . ILE A 1 296 ? 40.389 19.336 39.176 1.00 23.47 ? 292 ILE A CG2 1 ATOM 2287 C CD1 . ILE A 1 296 ? 38.578 18.787 36.678 1.00 20.45 ? 292 ILE A CD1 1 ATOM 2288 N N . THR A 1 297 ? 40.560 22.916 39.827 1.00 24.92 ? 293 THR A N 1 ATOM 2289 C CA . THR A 1 297 ? 41.746 23.576 40.402 1.00 27.72 ? 293 THR A CA 1 ATOM 2290 C C . THR A 1 297 ? 41.410 24.762 41.292 1.00 28.98 ? 293 THR A C 1 ATOM 2291 O O . THR A 1 297 ? 40.313 25.361 41.217 1.00 28.48 ? 293 THR A O 1 ATOM 2292 C CB . THR A 1 297 ? 42.715 24.068 39.298 1.00 26.55 ? 293 THR A CB 1 ATOM 2293 O OG1 . THR A 1 297 ? 42.100 25.133 38.553 1.00 27.25 ? 293 THR A OG1 1 ATOM 2294 C CG2 . THR A 1 297 ? 43.134 22.907 38.388 1.00 27.88 ? 293 THR A CG2 1 ATOM 2295 N N . THR A 1 298 ? 42.374 25.080 42.166 1.00 31.68 ? 294 THR A N 1 ATOM 2296 C CA . THR A 1 298 ? 42.330 26.262 42.995 1.00 34.74 ? 294 THR A CA 1 ATOM 2297 C C . THR A 1 298 ? 43.579 27.105 42.733 1.00 34.84 ? 294 THR A C 1 ATOM 2298 O O . THR A 1 298 ? 44.700 26.612 42.912 1.00 36.79 ? 294 THR A O 1 ATOM 2299 C CB . THR A 1 298 ? 42.263 25.897 44.495 1.00 35.52 ? 294 THR A CB 1 ATOM 2300 O OG1 . THR A 1 298 ? 41.100 25.080 44.723 1.00 38.20 ? 294 THR A OG1 1 ATOM 2301 C CG2 . THR A 1 298 ? 42.173 27.171 45.344 1.00 37.50 ? 294 THR A CG2 1 ATOM 2302 N N . PRO A 1 299 ? 43.398 28.342 42.252 1.00 34.16 ? 295 PRO A N 1 ATOM 2303 C CA . PRO A 1 299 ? 42.125 28.959 41.837 1.00 32.80 ? 295 PRO A CA 1 ATOM 2304 C C . PRO A 1 299 ? 41.525 28.290 40.581 1.00 31.02 ? 295 PRO A C 1 ATOM 2305 O O . PRO A 1 299 ? 42.229 27.570 39.848 1.00 30.46 ? 295 PRO A O 1 ATOM 2306 C CB . PRO A 1 299 ? 42.505 30.391 41.480 1.00 33.31 ? 295 PRO A CB 1 ATOM 2307 C CG . PRO A 1 299 ? 43.951 30.567 41.929 1.00 34.27 ? 295 PRO A CG 1 ATOM 2308 C CD . PRO A 1 299 ? 44.555 29.240 42.059 1.00 34.78 ? 295 PRO A CD 1 ATOM 2309 N N . ALA A 1 300 ? 40.240 28.535 40.343 1.00 29.41 ? 296 ALA A N 1 ATOM 2310 C CA . ALA A 1 300 ? 39.573 27.942 39.149 1.00 27.66 ? 296 ALA A CA 1 ATOM 2311 C C . ALA A 1 300 ? 40.259 28.466 37.912 1.00 26.21 ? 296 ALA A C 1 ATOM 2312 O O . ALA A 1 300 ? 40.532 29.664 37.813 1.00 27.60 ? 296 ALA A O 1 ATOM 2313 C CB . ALA A 1 300 ? 38.087 28.335 39.108 1.00 27.25 ? 296 ALA A CB 1 ATOM 2314 N N . GLY A 1 301 ? 40.503 27.585 36.951 1.00 26.11 ? 297 GLY A N 1 ATOM 2315 C CA . GLY A 1 301 ? 40.987 28.014 35.655 1.00 26.15 ? 297 GLY A CA 1 ATOM 2316 C C . GLY A 1 301 ? 42.513 28.201 35.639 1.00 27.20 ? 297 GLY A C 1 ATOM 2317 O O . GLY A 1 301 ? 43.053 28.579 34.622 1.00 27.85 ? 297 GLY A O 1 ATOM 2318 N N . SER A 1 302 ? 43.181 27.899 36.757 1.00 27.41 ? 298 SER A N 1 ATOM 2319 C CA . SER A 1 302 ? 44.629 28.137 36.891 1.00 28.10 ? 298 SER A CA 1 ATOM 2320 C C . SER A 1 302 ? 45.527 27.084 36.236 1.00 28.46 ? 298 SER A C 1 ATOM 2321 O O . SER A 1 302 ? 46.740 27.322 36.045 1.00 30.03 ? 298 SER A O 1 ATOM 2322 C CB . SER A 1 302 ? 44.981 28.335 38.365 1.00 26.89 ? 298 SER A CB 1 ATOM 2323 O OG . SER A 1 302 ? 44.923 27.109 39.067 1.00 29.49 ? 298 SER A OG 1 ATOM 2324 N N . ASP A 1 303 ? 44.973 25.940 35.844 1.00 26.41 ? 299 ASP A N 1 ATOM 2325 C CA . ASP A 1 303 ? 45.743 24.981 35.058 1.00 25.77 ? 299 ASP A CA 1 ATOM 2326 C C . ASP A 1 303 ? 44.758 24.261 34.162 1.00 23.25 ? 299 ASP A C 1 ATOM 2327 O O . ASP A 1 303 ? 44.400 23.132 34.448 1.00 23.61 ? 299 ASP A O 1 ATOM 2328 C CB . ASP A 1 303 ? 46.439 23.967 35.996 1.00 26.52 ? 299 ASP A CB 1 ATOM 2329 C CG . ASP A 1 303 ? 47.446 23.069 35.280 1.00 30.20 ? 299 ASP A CG 1 ATOM 2330 O OD1 . ASP A 1 303 ? 47.445 23.006 34.024 1.00 30.52 ? 299 ASP A OD1 1 ATOM 2331 O OD2 . ASP A 1 303 ? 48.220 22.368 35.989 1.00 32.37 ? 299 ASP A OD2 1 ATOM 2332 N N . TYR A 1 304 ? 44.354 24.925 33.089 1.00 23.83 ? 300 TYR A N 1 ATOM 2333 C CA . TYR A 1 304 ? 43.309 24.376 32.215 1.00 22.42 ? 300 TYR A CA 1 ATOM 2334 C C . TYR A 1 304 ? 43.752 23.126 31.532 1.00 23.17 ? 300 TYR A C 1 ATOM 2335 O O . TYR A 1 304 ? 42.982 22.197 31.326 1.00 20.48 ? 300 TYR A O 1 ATOM 2336 C CB . TYR A 1 304 ? 42.833 25.399 31.214 1.00 22.46 ? 300 TYR A CB 1 ATOM 2337 C CG . TYR A 1 304 ? 41.470 25.038 30.611 1.00 21.25 ? 300 TYR A CG 1 ATOM 2338 C CD1 . TYR A 1 304 ? 40.338 24.985 31.419 1.00 21.91 ? 300 TYR A CD1 1 ATOM 2339 C CD2 . TYR A 1 304 ? 41.339 24.831 29.261 1.00 23.78 ? 300 TYR A CD2 1 ATOM 2340 C CE1 . TYR A 1 304 ? 39.055 24.717 30.862 1.00 21.59 ? 300 TYR A CE1 1 ATOM 2341 C CE2 . TYR A 1 304 ? 40.071 24.547 28.696 1.00 23.60 ? 300 TYR A CE2 1 ATOM 2342 C CZ . TYR A 1 304 ? 38.956 24.524 29.518 1.00 24.04 ? 300 TYR A CZ 1 ATOM 2343 O OH . TYR A 1 304 ? 37.730 24.250 28.948 1.00 22.72 ? 300 TYR A OH 1 ATOM 2344 N N . SER A 1 305 ? 45.046 23.039 31.192 1.00 22.20 ? 301 SER A N 1 ATOM 2345 C CA . SER A 1 305 ? 45.574 21.738 30.760 1.00 22.66 ? 301 SER A CA 1 ATOM 2346 C C . SER A 1 305 ? 45.273 20.560 31.697 1.00 21.19 ? 301 SER A C 1 ATOM 2347 O O . SER A 1 305 ? 44.874 19.476 31.268 1.00 21.10 ? 301 SER A O 1 ATOM 2348 C CB . SER A 1 305 ? 47.120 21.848 30.536 1.00 24.05 ? 301 SER A CB 1 ATOM 2349 O OG . SER A 1 305 ? 47.626 20.625 30.030 1.00 27.46 ? 301 SER A OG 1 ATOM 2350 N N . TYR A 1 306 ? 45.497 20.753 33.016 1.00 21.72 ? 302 TYR A N 1 ATOM 2351 C CA . TYR A 1 306 ? 45.168 19.720 33.964 1.00 22.67 ? 302 TYR A CA 1 ATOM 2352 C C . TYR A 1 306 ? 43.640 19.464 34.022 1.00 20.75 ? 302 TYR A C 1 ATOM 2353 O O . TYR A 1 306 ? 43.236 18.298 34.108 1.00 22.00 ? 302 TYR A O 1 ATOM 2354 C CB . TYR A 1 306 ? 45.712 20.056 35.380 1.00 22.87 ? 302 TYR A CB 1 ATOM 2355 C CG . TYR A 1 306 ? 45.330 19.006 36.372 1.00 25.53 ? 302 TYR A CG 1 ATOM 2356 C CD1 . TYR A 1 306 ? 45.899 17.734 36.319 1.00 28.74 ? 302 TYR A CD1 1 ATOM 2357 C CD2 . TYR A 1 306 ? 44.332 19.243 37.334 1.00 27.83 ? 302 TYR A CD2 1 ATOM 2358 C CE1 . TYR A 1 306 ? 45.529 16.731 37.211 1.00 32.08 ? 302 TYR A CE1 1 ATOM 2359 C CE2 . TYR A 1 306 ? 43.955 18.225 38.237 1.00 29.01 ? 302 TYR A CE2 1 ATOM 2360 C CZ . TYR A 1 306 ? 44.555 16.985 38.163 1.00 31.21 ? 302 TYR A CZ 1 ATOM 2361 O OH . TYR A 1 306 ? 44.224 15.943 39.022 1.00 35.15 ? 302 TYR A OH 1 ATOM 2362 N N . SER A 1 307 ? 42.853 20.546 34.002 1.00 22.33 ? 303 SER A N 1 ATOM 2363 C CA . SER A 1 307 ? 41.373 20.416 34.024 1.00 20.84 ? 303 SER A CA 1 ATOM 2364 C C . SER A 1 307 ? 40.902 19.489 32.925 1.00 20.23 ? 303 SER A C 1 ATOM 2365 O O . SER A 1 307 ? 40.081 18.608 33.143 1.00 19.79 ? 303 SER A O 1 ATOM 2366 C CB . SER A 1 307 ? 40.774 21.800 33.814 1.00 20.90 ? 303 SER A CB 1 ATOM 2367 O OG . SER A 1 307 ? 40.907 22.568 34.992 1.00 22.21 ? 303 SER A OG 1 ATOM 2368 N N . VAL A 1 308 ? 41.462 19.674 31.725 1.00 19.72 ? 304 VAL A N 1 ATOM 2369 C CA . VAL A 1 308 ? 41.070 18.831 30.587 1.00 18.77 ? 304 VAL A CA 1 ATOM 2370 C C . VAL A 1 308 ? 41.503 17.412 30.806 1.00 19.29 ? 304 VAL A C 1 ATOM 2371 O O . VAL A 1 308 ? 40.752 16.466 30.656 1.00 19.08 ? 304 VAL A O 1 ATOM 2372 C CB . VAL A 1 308 ? 41.636 19.396 29.253 1.00 18.73 ? 304 VAL A CB 1 ATOM 2373 C CG1 . VAL A 1 308 ? 41.367 18.424 28.131 1.00 20.66 ? 304 VAL A CG1 1 ATOM 2374 C CG2 . VAL A 1 308 ? 41.052 20.792 28.963 1.00 18.30 ? 304 VAL A CG2 1 ATOM 2375 N N . LYS A 1 309 ? 42.808 17.246 31.151 1.00 20.37 ? 305 LYS A N 1 ATOM 2376 C CA . LYS A 1 309 ? 43.274 15.922 31.427 1.00 22.27 ? 305 LYS A CA 1 ATOM 2377 C C . LYS A 1 309 ? 42.461 15.155 32.486 1.00 20.33 ? 305 LYS A C 1 ATOM 2378 O O . LYS A 1 309 ? 42.052 14.014 32.265 1.00 20.40 ? 305 LYS A O 1 ATOM 2379 C CB . LYS A 1 309 ? 44.780 15.977 31.846 1.00 23.77 ? 305 LYS A CB 1 ATOM 2380 C CG . LYS A 1 309 ? 45.361 14.598 31.873 1.00 27.79 ? 305 LYS A CG 1 ATOM 2381 C CD . LYS A 1 309 ? 46.890 14.625 32.140 1.00 30.72 ? 305 LYS A CD 1 ATOM 2382 C CE . LYS A 1 309 ? 47.158 14.643 33.621 1.00 33.01 ? 305 LYS A CE 1 ATOM 2383 N NZ . LYS A 1 309 ? 48.620 14.334 33.882 1.00 33.78 ? 305 LYS A NZ 1 ATOM 2384 N N . ALA A 1 310 ? 42.260 15.791 33.641 1.00 21.68 ? 306 ALA A N 1 ATOM 2385 C CA . ALA A 1 310 ? 41.664 15.148 34.806 1.00 20.87 ? 306 ALA A CA 1 ATOM 2386 C C . ALA A 1 310 ? 40.200 14.750 34.527 1.00 19.40 ? 306 ALA A C 1 ATOM 2387 O O . ALA A 1 310 ? 39.775 13.637 34.795 1.00 19.99 ? 306 ALA A O 1 ATOM 2388 C CB . ALA A 1 310 ? 41.729 16.080 35.961 1.00 20.94 ? 306 ALA A CB 1 ATOM 2389 N N . SER A 1 311 ? 39.493 15.662 33.868 1.00 20.15 ? 307 SER A N 1 ATOM 2390 C CA . SER A 1 311 ? 38.061 15.412 33.598 1.00 19.75 ? 307 SER A CA 1 ATOM 2391 C C . SER A 1 311 ? 37.828 14.352 32.545 1.00 18.60 ? 307 SER A C 1 ATOM 2392 O O . SER A 1 311 ? 37.005 13.478 32.716 1.00 18.21 ? 307 SER A O 1 ATOM 2393 C CB . SER A 1 311 ? 37.382 16.738 33.226 1.00 18.07 ? 307 SER A CB 1 ATOM 2394 O OG . SER A 1 311 ? 37.915 17.339 32.028 1.00 20.09 ? 307 SER A OG 1 ATOM 2395 N N . ILE A 1 312 ? 38.594 14.424 31.437 1.00 18.64 ? 308 ILE A N 1 ATOM 2396 C CA . ILE A 1 312 ? 38.452 13.443 30.382 1.00 18.73 ? 308 ILE A CA 1 ATOM 2397 C C . ILE A 1 312 ? 38.910 12.053 30.854 1.00 19.27 ? 308 ILE A C 1 ATOM 2398 O O . ILE A 1 312 ? 38.236 11.085 30.616 1.00 19.30 ? 308 ILE A O 1 ATOM 2399 C CB . ILE A 1 312 ? 39.117 13.913 29.070 1.00 19.47 ? 308 ILE A CB 1 ATOM 2400 C CG1 . ILE A 1 312 ? 38.503 15.247 28.569 1.00 18.74 ? 308 ILE A CG1 1 ATOM 2401 C CG2 . ILE A 1 312 ? 39.010 12.802 28.039 1.00 18.87 ? 308 ILE A CG2 1 ATOM 2402 C CD1 . ILE A 1 312 ? 36.881 15.163 28.411 1.00 20.34 ? 308 ILE A CD1 1 ATOM 2403 N N . LEU A 1 313 ? 40.034 12.007 31.606 1.00 20.13 ? 309 LEU A N 1 ATOM 2404 C CA . LEU A 1 313 ? 40.475 10.755 32.150 1.00 20.81 ? 309 LEU A CA 1 ATOM 2405 C C . LEU A 1 313 ? 39.534 10.183 33.237 1.00 19.89 ? 309 LEU A C 1 ATOM 2406 O O . LEU A 1 313 ? 39.402 8.961 33.340 1.00 21.44 ? 309 LEU A O 1 ATOM 2407 C CB . LEU A 1 313 ? 41.932 10.884 32.658 1.00 20.84 ? 309 LEU A CB 1 ATOM 2408 C CG . LEU A 1 313 ? 42.923 11.023 31.491 1.00 23.96 ? 309 LEU A CG 1 ATOM 2409 C CD1 . LEU A 1 313 ? 44.314 11.158 32.147 1.00 23.77 ? 309 LEU A CD1 1 ATOM 2410 C CD2 . LEU A 1 313 ? 42.798 9.824 30.479 1.00 24.24 ? 309 LEU A CD2 1 ATOM 2411 N N . ALA A 1 314 ? 38.815 11.073 33.954 1.00 20.04 ? 310 ALA A N 1 ATOM 2412 C CA . ALA A 1 314 ? 37.814 10.619 34.951 1.00 21.01 ? 310 ALA A CA 1 ATOM 2413 C C . ALA A 1 314 ? 36.633 9.920 34.286 1.00 20.29 ? 310 ALA A C 1 ATOM 2414 O O . ALA A 1 314 ? 35.953 9.099 34.916 1.00 20.94 ? 310 ALA A O 1 ATOM 2415 C CB . ALA A 1 314 ? 37.333 11.803 35.798 1.00 20.97 ? 310 ALA A CB 1 ATOM 2416 N N . GLY A 1 315 ? 36.365 10.255 33.004 1.00 19.30 ? 311 GLY A N 1 ATOM 2417 C CA . GLY A 1 315 ? 35.324 9.589 32.277 1.00 18.57 ? 311 GLY A CA 1 ATOM 2418 C C . GLY A 1 315 ? 34.227 10.526 31.734 1.00 18.22 ? 311 GLY A C 1 ATOM 2419 O O . GLY A 1 315 ? 33.246 10.030 31.149 1.00 18.60 ? 311 GLY A O 1 ATOM 2420 N N . LEU A 1 316 ? 34.438 11.827 31.855 1.00 17.70 ? 312 LEU A N 1 ATOM 2421 C CA . LEU A 1 316 ? 33.395 12.765 31.291 1.00 17.78 ? 312 LEU A CA 1 ATOM 2422 C C . LEU A 1 316 ? 33.440 12.669 29.783 1.00 18.34 ? 312 LEU A C 1 ATOM 2423 O O . LEU A 1 316 ? 34.520 12.455 29.190 1.00 18.35 ? 312 LEU A O 1 ATOM 2424 C CB . LEU A 1 316 ? 33.554 14.211 31.743 1.00 16.43 ? 312 LEU A CB 1 ATOM 2425 C CG . LEU A 1 316 ? 33.078 14.546 33.164 1.00 17.30 ? 312 LEU A CG 1 ATOM 2426 C CD1 . LEU A 1 316 ? 34.000 13.961 34.300 1.00 17.96 ? 312 LEU A CD1 1 ATOM 2427 C CD2 . LEU A 1 316 ? 33.038 16.047 33.336 1.00 18.54 ? 312 LEU A CD2 1 ATOM 2428 N N . ASP A 1 317 ? 32.287 12.814 29.129 1.00 16.25 ? 313 ASP A N 1 ATOM 2429 C CA . ASP A 1 317 ? 32.160 12.620 27.653 1.00 15.95 ? 313 ASP A CA 1 ATOM 2430 C C . ASP A 1 317 ? 32.010 13.923 26.908 1.00 16.58 ? 313 ASP A C 1 ATOM 2431 O O . ASP A 1 317 ? 32.571 14.071 25.818 1.00 16.92 ? 313 ASP A O 1 ATOM 2432 C CB . ASP A 1 317 ? 30.959 11.711 27.304 1.00 15.55 ? 313 ASP A CB 1 ATOM 2433 C CG . ASP A 1 317 ? 31.003 10.426 28.069 1.00 18.53 ? 313 ASP A CG 1 ATOM 2434 O OD1 . ASP A 1 317 ? 32.087 9.760 28.012 1.00 17.46 ? 313 ASP A OD1 1 ATOM 2435 O OD2 . ASP A 1 317 ? 30.030 10.019 28.705 1.00 18.84 ? 313 ASP A OD2 1 ATOM 2436 N N . MET A 1 318 ? 31.188 14.845 27.455 1.00 15.52 ? 314 MET A N 1 ATOM 2437 C CA . MET A 1 318 ? 30.953 16.144 26.812 1.00 14.27 ? 314 MET A CA 1 ATOM 2438 C C . MET A 1 318 ? 31.253 17.250 27.816 1.00 15.17 ? 314 MET A C 1 ATOM 2439 O O . MET A 1 318 ? 30.863 17.135 28.989 1.00 15.80 ? 314 MET A O 1 ATOM 2440 C CB . MET A 1 318 ? 29.486 16.206 26.327 1.00 14.61 ? 314 MET A CB 1 ATOM 2441 C CG . MET A 1 318 ? 29.176 17.561 25.623 1.00 15.22 ? 314 MET A CG 1 ATOM 2442 S SD . MET A 1 318 ? 27.437 17.735 25.088 1.00 15.56 ? 314 MET A SD 1 ATOM 2443 C CE . MET A 1 318 ? 27.388 16.526 23.770 1.00 15.56 ? 314 MET A CE 1 ATOM 2444 N N . ILE A 1 319 ? 31.964 18.288 27.390 1.00 13.63 ? 315 ILE A N 1 ATOM 2445 C CA . ILE A 1 319 ? 32.314 19.389 28.251 1.00 14.82 ? 315 ILE A CA 1 ATOM 2446 C C . ILE A 1 319 ? 31.506 20.608 27.904 1.00 13.75 ? 315 ILE A C 1 ATOM 2447 O O . ILE A 1 319 ? 31.506 21.084 26.754 1.00 14.39 ? 315 ILE A O 1 ATOM 2448 C CB . ILE A 1 319 ? 33.871 19.689 28.175 1.00 15.53 ? 315 ILE A CB 1 ATOM 2449 C CG1 . ILE A 1 319 ? 34.654 18.410 28.538 1.00 19.00 ? 315 ILE A CG1 1 ATOM 2450 C CG2 . ILE A 1 319 ? 34.230 20.890 29.091 1.00 15.70 ? 315 ILE A CG2 1 ATOM 2451 C CD1 . ILE A 1 319 ? 34.332 17.767 29.956 1.00 16.33 ? 315 ILE A CD1 1 ATOM 2452 N N . MET A 1 320 ? 30.764 21.077 28.922 1.00 13.68 ? 316 MET A N 1 ATOM 2453 C CA . MET A 1 320 ? 30.078 22.379 28.858 1.00 14.16 ? 316 MET A CA 1 ATOM 2454 C C . MET A 1 320 ? 31.155 23.433 29.079 1.00 14.57 ? 316 MET A C 1 ATOM 2455 O O . MET A 1 320 ? 31.487 23.803 30.208 1.00 15.14 ? 316 MET A O 1 ATOM 2456 C CB . MET A 1 320 ? 28.971 22.398 29.969 1.00 14.80 ? 316 MET A CB 1 ATOM 2457 C CG . MET A 1 320 ? 28.147 23.686 29.903 1.00 13.98 ? 316 MET A CG 1 ATOM 2458 S SD . MET A 1 320 ? 26.944 23.744 31.265 1.00 14.86 ? 316 MET A SD 1 ATOM 2459 C CE . MET A 1 320 ? 26.007 22.270 30.917 1.00 15.51 ? 316 MET A CE 1 ATOM 2460 N N . VAL A 1 321 ? 31.709 23.942 27.978 1.00 14.58 ? 317 VAL A N 1 ATOM 2461 C CA . VAL A 1 321 ? 32.975 24.671 28.083 1.00 14.91 ? 317 VAL A CA 1 ATOM 2462 C C . VAL A 1 321 ? 32.787 25.947 28.925 1.00 15.82 ? 317 VAL A C 1 ATOM 2463 O O . VAL A 1 321 ? 33.501 26.142 29.915 1.00 16.88 ? 317 VAL A O 1 ATOM 2464 C CB . VAL A 1 321 ? 33.601 24.895 26.714 1.00 15.00 ? 317 VAL A CB 1 ATOM 2465 C CG1 . VAL A 1 321 ? 34.910 25.723 26.897 1.00 17.91 ? 317 VAL A CG1 1 ATOM 2466 C CG2 . VAL A 1 321 ? 33.899 23.582 26.056 1.00 16.41 ? 317 VAL A CG2 1 ATOM 2467 N N . PRO A 1 322 ? 31.799 26.813 28.622 1.00 14.72 ? 318 PRO A N 1 ATOM 2468 C CA . PRO A 1 322 ? 31.043 26.831 27.375 1.00 14.56 ? 318 PRO A CA 1 ATOM 2469 C C . PRO A 1 322 ? 31.521 27.894 26.422 1.00 15.55 ? 318 PRO A C 1 ATOM 2470 O O . PRO A 1 322 ? 30.964 28.034 25.356 1.00 15.57 ? 318 PRO A O 1 ATOM 2471 C CB . PRO A 1 322 ? 29.627 27.201 27.872 1.00 16.12 ? 318 PRO A CB 1 ATOM 2472 C CG . PRO A 1 322 ? 29.893 28.239 28.986 1.00 16.60 ? 318 PRO A CG 1 ATOM 2473 C CD . PRO A 1 322 ? 31.237 27.755 29.641 1.00 14.85 ? 318 PRO A CD 1 ATOM 2474 N N . ASN A 1 323 ? 32.553 28.678 26.801 1.00 17.18 ? 319 ASN A N 1 ATOM 2475 C CA . ASN A 1 323 ? 32.943 29.824 25.994 1.00 17.76 ? 319 ASN A CA 1 ATOM 2476 C C . ASN A 1 323 ? 34.275 29.663 25.304 1.00 19.25 ? 319 ASN A C 1 ATOM 2477 O O . ASN A 1 323 ? 34.376 30.004 24.120 1.00 20.04 ? 319 ASN A O 1 ATOM 2478 C CB . ASN A 1 323 ? 32.999 31.059 26.898 1.00 19.04 ? 319 ASN A CB 1 ATOM 2479 C CG . ASN A 1 323 ? 31.638 31.400 27.485 1.00 20.37 ? 319 ASN A CG 1 ATOM 2480 O OD1 . ASN A 1 323 ? 30.600 31.300 26.787 1.00 19.18 ? 319 ASN A OD1 1 ATOM 2481 N ND2 . ASN A 1 323 ? 31.622 31.769 28.769 1.00 21.40 ? 319 ASN A ND2 1 ATOM 2482 N N . LYS A 1 324 ? 35.264 29.182 26.046 1.00 20.45 ? 320 LYS A N 1 ATOM 2483 C CA . LYS A 1 324 ? 36.640 29.040 25.481 1.00 20.87 ? 320 LYS A CA 1 ATOM 2484 C C . LYS A 1 324 ? 36.843 27.722 24.709 1.00 20.21 ? 320 LYS A C 1 ATOM 2485 O O . LYS A 1 324 ? 37.719 26.877 24.998 1.00 19.46 ? 320 LYS A O 1 ATOM 2486 C CB . LYS A 1 324 ? 37.685 29.218 26.597 1.00 21.90 ? 320 LYS A CB 1 ATOM 2487 C CG A LYS A 1 324 ? 37.492 30.448 27.409 0.60 24.19 ? 320 LYS A CG 1 ATOM 2488 C CG B LYS A 1 324 ? 37.406 28.434 27.836 0.40 22.50 ? 320 LYS A CG 1 ATOM 2489 C CD A LYS A 1 324 ? 37.500 31.711 26.566 0.60 28.98 ? 320 LYS A CD 1 ATOM 2490 C CD B LYS A 1 324 ? 38.405 27.344 28.068 0.40 27.00 ? 320 LYS A CD 1 ATOM 2491 C CE A LYS A 1 324 ? 38.264 32.863 27.217 0.60 32.79 ? 320 LYS A CE 1 ATOM 2492 C CE B LYS A 1 324 ? 39.529 27.854 28.989 0.40 28.84 ? 320 LYS A CE 1 ATOM 2493 N NZ A LYS A 1 324 ? 38.592 32.653 28.647 0.60 34.36 ? 320 LYS A NZ 1 ATOM 2494 N NZ B LYS A 1 324 ? 39.029 28.446 30.232 0.40 31.19 ? 320 LYS A NZ 1 ATOM 2495 N N . TYR A 1 325 ? 36.041 27.542 23.649 1.00 18.44 ? 321 TYR A N 1 ATOM 2496 C CA . TYR A 1 325 ? 36.087 26.311 22.913 1.00 18.22 ? 321 TYR A CA 1 ATOM 2497 C C . TYR A 1 325 ? 37.399 26.134 22.126 1.00 18.37 ? 321 TYR A C 1 ATOM 2498 O O . TYR A 1 325 ? 37.841 25.007 21.962 1.00 19.63 ? 321 TYR A O 1 ATOM 2499 C CB . TYR A 1 325 ? 34.859 26.177 21.939 1.00 18.83 ? 321 TYR A CB 1 ATOM 2500 C CG . TYR A 1 325 ? 34.790 27.349 20.990 1.00 17.67 ? 321 TYR A CG 1 ATOM 2501 C CD1 . TYR A 1 325 ? 35.595 27.364 19.817 1.00 16.95 ? 321 TYR A CD1 1 ATOM 2502 C CD2 . TYR A 1 325 ? 34.021 28.493 21.271 1.00 18.77 ? 321 TYR A CD2 1 ATOM 2503 C CE1 . TYR A 1 325 ? 35.610 28.466 18.975 1.00 18.47 ? 321 TYR A CE1 1 ATOM 2504 C CE2 . TYR A 1 325 ? 34.022 29.582 20.430 1.00 20.15 ? 321 TYR A CE2 1 ATOM 2505 C CZ . TYR A 1 325 ? 34.835 29.577 19.293 1.00 20.69 ? 321 TYR A CZ 1 ATOM 2506 O OH . TYR A 1 325 ? 34.832 30.679 18.502 1.00 23.11 ? 321 TYR A OH 1 ATOM 2507 N N . GLN A 1 326 ? 38.028 27.230 21.698 1.00 20.14 ? 322 GLN A N 1 ATOM 2508 C CA . GLN A 1 326 ? 39.250 27.037 20.867 1.00 20.29 ? 322 GLN A CA 1 ATOM 2509 C C . GLN A 1 326 ? 40.350 26.467 21.773 1.00 19.28 ? 322 GLN A C 1 ATOM 2510 O O . GLN A 1 326 ? 41.051 25.524 21.368 1.00 20.70 ? 322 GLN A O 1 ATOM 2511 C CB . GLN A 1 326 ? 39.690 28.383 20.293 1.00 21.56 ? 322 GLN A CB 1 ATOM 2512 C CG . GLN A 1 326 ? 40.921 28.287 19.344 1.00 26.41 ? 322 GLN A CG 1 ATOM 2513 C CD . GLN A 1 326 ? 41.417 29.706 19.005 1.00 38.24 ? 322 GLN A CD 1 ATOM 2514 O OE1 . GLN A 1 326 ? 40.621 30.587 18.644 1.00 43.59 ? 322 GLN A OE1 1 ATOM 2515 N NE2 . GLN A 1 326 ? 42.716 29.940 19.162 1.00 44.40 ? 322 GLN A NE2 1 ATOM 2516 N N . GLN A 1 327 ? 40.440 27.011 22.975 1.00 20.24 ? 323 GLN A N 1 ATOM 2517 C CA . GLN A 1 327 ? 41.402 26.508 23.994 1.00 21.55 ? 323 GLN A CA 1 ATOM 2518 C C . GLN A 1 327 ? 41.120 25.076 24.403 1.00 20.24 ? 323 GLN A C 1 ATOM 2519 O O . GLN A 1 327 ? 41.994 24.220 24.482 1.00 20.08 ? 323 GLN A O 1 ATOM 2520 C CB . GLN A 1 327 ? 41.387 27.409 25.209 1.00 22.42 ? 323 GLN A CB 1 ATOM 2521 C CG . GLN A 1 327 ? 42.439 26.981 26.190 1.00 28.76 ? 323 GLN A CG 1 ATOM 2522 C CD . GLN A 1 327 ? 42.550 27.929 27.386 1.00 37.25 ? 323 GLN A CD 1 ATOM 2523 O OE1 . GLN A 1 327 ? 41.757 28.868 27.535 1.00 42.57 ? 323 GLN A OE1 1 ATOM 2524 N NE2 . GLN A 1 327 ? 43.525 27.673 28.247 1.00 37.20 ? 323 GLN A NE2 1 ATOM 2525 N N . PHE A 1 328 ? 39.834 24.783 24.685 1.00 17.94 ? 324 PHE A N 1 ATOM 2526 C CA . PHE A 1 328 ? 39.491 23.436 25.047 1.00 17.81 ? 324 PHE A CA 1 ATOM 2527 C C . PHE A 1 328 ? 39.915 22.421 23.956 1.00 16.51 ? 324 PHE A C 1 ATOM 2528 O O . PHE A 1 328 ? 40.514 21.347 24.229 1.00 17.57 ? 324 PHE A O 1 ATOM 2529 C CB . PHE A 1 328 ? 37.928 23.331 25.300 1.00 16.66 ? 324 PHE A CB 1 ATOM 2530 C CG . PHE A 1 328 ? 37.498 21.930 25.529 1.00 17.78 ? 324 PHE A CG 1 ATOM 2531 C CD1 . PHE A 1 328 ? 37.824 21.291 26.736 1.00 17.08 ? 324 PHE A CD1 1 ATOM 2532 C CD2 . PHE A 1 328 ? 36.828 21.191 24.531 1.00 14.81 ? 324 PHE A CD2 1 ATOM 2533 C CE1 . PHE A 1 328 ? 37.497 19.946 26.948 1.00 16.56 ? 324 PHE A CE1 1 ATOM 2534 C CE2 . PHE A 1 328 ? 36.498 19.860 24.725 1.00 17.81 ? 324 PHE A CE2 1 ATOM 2535 C CZ . PHE A 1 328 ? 36.829 19.214 25.926 1.00 16.59 ? 324 PHE A CZ 1 ATOM 2536 N N . ILE A 1 329 ? 39.494 22.699 22.712 1.00 17.44 ? 325 ILE A N 1 ATOM 2537 C CA . ILE A 1 329 ? 39.746 21.795 21.622 1.00 16.73 ? 325 ILE A CA 1 ATOM 2538 C C . ILE A 1 329 ? 41.274 21.685 21.401 1.00 16.45 ? 325 ILE A C 1 ATOM 2539 O O . ILE A 1 329 ? 41.775 20.578 21.211 1.00 16.97 ? 325 ILE A O 1 ATOM 2540 C CB . ILE A 1 329 ? 39.056 22.329 20.333 1.00 17.58 ? 325 ILE A CB 1 ATOM 2541 C CG1 . ILE A 1 329 ? 37.518 22.172 20.520 1.00 18.46 ? 325 ILE A CG1 1 ATOM 2542 C CG2 . ILE A 1 329 ? 39.486 21.527 19.108 1.00 18.69 ? 325 ILE A CG2 1 ATOM 2543 C CD1 . ILE A 1 329 ? 36.793 22.861 19.390 1.00 20.18 ? 325 ILE A CD1 1 ATOM 2544 N N . SER A 1 330 ? 41.938 22.809 21.487 1.00 17.24 ? 326 SER A N 1 ATOM 2545 C CA . SER A 1 330 ? 43.414 22.784 21.233 1.00 18.46 ? 326 SER A CA 1 ATOM 2546 C C . SER A 1 330 ? 44.142 21.918 22.282 1.00 18.63 ? 326 SER A C 1 ATOM 2547 O O . SER A 1 330 ? 45.014 21.073 21.969 1.00 18.80 ? 326 SER A O 1 ATOM 2548 C CB . SER A 1 330 ? 43.933 24.196 21.241 1.00 18.49 ? 326 SER A CB 1 ATOM 2549 O OG . SER A 1 330 ? 45.394 24.158 20.969 1.00 19.15 ? 326 SER A OG 1 ATOM 2550 N N . ILE A 1 331 ? 43.775 22.120 23.547 1.00 18.07 ? 327 ILE A N 1 ATOM 2551 C CA . ILE A 1 331 ? 44.397 21.345 24.659 1.00 18.36 ? 327 ILE A CA 1 ATOM 2552 C C . ILE A 1 331 ? 44.091 19.908 24.583 1.00 18.87 ? 327 ILE A C 1 ATOM 2553 O O . ILE A 1 331 ? 44.948 19.042 24.720 1.00 20.33 ? 327 ILE A O 1 ATOM 2554 C CB . ILE A 1 331 ? 44.005 21.956 26.029 1.00 17.29 ? 327 ILE A CB 1 ATOM 2555 C CG1 . ILE A 1 331 ? 44.660 23.338 26.138 1.00 21.48 ? 327 ILE A CG1 1 ATOM 2556 C CG2 . ILE A 1 331 ? 44.333 21.005 27.189 1.00 18.42 ? 327 ILE A CG2 1 ATOM 2557 C CD1 . ILE A 1 331 ? 44.311 24.177 27.344 1.00 29.47 ? 327 ILE A CD1 1 ATOM 2558 N N . LEU A 1 332 ? 42.807 19.561 24.341 1.00 18.53 ? 328 LEU A N 1 ATOM 2559 C CA . LEU A 1 332 ? 42.503 18.173 24.265 1.00 17.87 ? 328 LEU A CA 1 ATOM 2560 C C . LEU A 1 332 ? 43.209 17.476 23.071 1.00 17.78 ? 328 LEU A C 1 ATOM 2561 O O . LEU A 1 332 ? 43.639 16.343 23.183 1.00 18.32 ? 328 LEU A O 1 ATOM 2562 C CB . LEU A 1 332 ? 40.937 17.991 24.203 1.00 17.33 ? 328 LEU A CB 1 ATOM 2563 C CG . LEU A 1 332 ? 40.438 16.553 24.197 1.00 19.85 ? 328 LEU A CG 1 ATOM 2564 C CD1 . LEU A 1 332 ? 41.038 15.622 25.277 1.00 19.61 ? 328 LEU A CD1 1 ATOM 2565 C CD2 . LEU A 1 332 ? 38.880 16.561 24.378 1.00 18.00 ? 328 LEU A CD2 1 ATOM 2566 N N . THR A 1 333 ? 43.277 18.202 21.944 1.00 18.61 ? 329 THR A N 1 ATOM 2567 C CA . THR A 1 333 ? 43.911 17.642 20.738 1.00 19.25 ? 329 THR A CA 1 ATOM 2568 C C . THR A 1 333 ? 45.399 17.358 21.061 1.00 20.09 ? 329 THR A C 1 ATOM 2569 O O . THR A 1 333 ? 45.911 16.285 20.732 1.00 20.52 ? 329 THR A O 1 ATOM 2570 C CB . THR A 1 333 ? 43.810 18.598 19.566 1.00 20.32 ? 329 THR A CB 1 ATOM 2571 O OG1 . THR A 1 333 ? 42.401 18.793 19.201 1.00 20.09 ? 329 THR A OG1 1 ATOM 2572 C CG2 . THR A 1 333 ? 44.483 17.958 18.329 1.00 19.48 ? 329 THR A CG2 1 ATOM 2573 N N . GLY A 1 334 ? 45.991 18.295 21.772 1.00 21.09 ? 330 GLY A N 1 ATOM 2574 C CA . GLY A 1 334 ? 47.432 18.160 22.207 1.00 20.95 ? 330 GLY A CA 1 ATOM 2575 C C . GLY A 1 334 ? 47.643 16.958 23.099 1.00 21.60 ? 330 GLY A C 1 ATOM 2576 O O . GLY A 1 334 ? 48.583 16.174 22.919 1.00 21.02 ? 330 GLY A O 1 ATOM 2577 N N . HIS A 1 335 ? 46.745 16.764 24.080 1.00 19.66 ? 331 HIS A N 1 ATOM 2578 C CA . HIS A 1 335 ? 46.813 15.595 24.937 1.00 20.33 ? 331 HIS A CA 1 ATOM 2579 C C . HIS A 1 335 ? 46.699 14.323 24.177 1.00 19.69 ? 331 HIS A C 1 ATOM 2580 O O . HIS A 1 335 ? 47.434 13.378 24.484 1.00 19.74 ? 331 HIS A O 1 ATOM 2581 C CB . HIS A 1 335 ? 45.746 15.647 26.050 1.00 20.16 ? 331 HIS A CB 1 ATOM 2582 C CG . HIS A 1 335 ? 46.100 16.595 27.154 1.00 22.69 ? 331 HIS A CG 1 ATOM 2583 N ND1 . HIS A 1 335 ? 45.171 17.297 27.896 1.00 25.50 ? 331 HIS A ND1 1 ATOM 2584 C CD2 . HIS A 1 335 ? 47.322 16.962 27.636 1.00 22.52 ? 331 HIS A CD2 1 ATOM 2585 C CE1 . HIS A 1 335 ? 45.799 18.056 28.788 1.00 22.35 ? 331 HIS A CE1 1 ATOM 2586 N NE2 . HIS A 1 335 ? 47.105 17.876 28.645 1.00 29.77 ? 331 HIS A NE2 1 ATOM 2587 N N . VAL A 1 336 ? 45.779 14.224 23.185 1.00 18.77 ? 332 VAL A N 1 ATOM 2588 C CA . VAL A 1 336 ? 45.651 12.991 22.437 1.00 19.37 ? 332 VAL A CA 1 ATOM 2589 C C . VAL A 1 336 ? 46.938 12.773 21.563 1.00 20.51 ? 332 VAL A C 1 ATOM 2590 O O . VAL A 1 336 ? 47.488 11.654 21.540 1.00 22.86 ? 332 VAL A O 1 ATOM 2591 C CB . VAL A 1 336 ? 44.389 13.065 21.539 1.00 19.15 ? 332 VAL A CB 1 ATOM 2592 C CG1 . VAL A 1 336 ? 44.295 11.835 20.706 1.00 19.99 ? 332 VAL A CG1 1 ATOM 2593 C CG2 . VAL A 1 336 ? 43.145 13.096 22.478 1.00 19.88 ? 332 VAL A CG2 1 ATOM 2594 N N . ASN A 1 337 ? 47.396 13.846 20.947 1.00 21.94 ? 333 ASN A N 1 ATOM 2595 C CA . ASN A 1 337 ? 48.577 13.747 20.029 1.00 24.78 ? 333 ASN A CA 1 ATOM 2596 C C . ASN A 1 337 ? 49.788 13.313 20.805 1.00 25.85 ? 333 ASN A C 1 ATOM 2597 O O . ASN A 1 337 ? 50.674 12.615 20.267 1.00 26.96 ? 333 ASN A O 1 ATOM 2598 C CB . ASN A 1 337 ? 48.858 15.114 19.403 1.00 24.45 ? 333 ASN A CB 1 ATOM 2599 C CG . ASN A 1 337 ? 47.954 15.423 18.231 1.00 26.16 ? 333 ASN A CG 1 ATOM 2600 O OD1 . ASN A 1 337 ? 47.301 14.504 17.678 1.00 26.52 ? 333 ASN A OD1 1 ATOM 2601 N ND2 . ASN A 1 337 ? 47.906 16.707 17.814 1.00 27.46 ? 333 ASN A ND2 1 ATOM 2602 N N . GLY A 1 338 ? 49.849 13.763 22.047 1.00 25.16 ? 334 GLY A N 1 ATOM 2603 C CA . GLY A 1 338 ? 50.944 13.444 22.961 1.00 25.00 ? 334 GLY A CA 1 ATOM 2604 C C . GLY A 1 338 ? 50.848 12.094 23.632 1.00 26.22 ? 334 GLY A C 1 ATOM 2605 O O . GLY A 1 338 ? 51.775 11.708 24.390 1.00 26.57 ? 334 GLY A O 1 ATOM 2606 N N . GLY A 1 339 ? 49.738 11.364 23.424 1.00 24.35 ? 335 GLY A N 1 ATOM 2607 C CA . GLY A 1 339 ? 49.509 10.096 24.104 1.00 24.37 ? 335 GLY A CA 1 ATOM 2608 C C . GLY A 1 339 ? 49.061 10.158 25.558 1.00 24.20 ? 335 GLY A C 1 ATOM 2609 O O . GLY A 1 339 ? 48.966 9.119 26.224 1.00 27.24 ? 335 GLY A O 1 ATOM 2610 N N . VAL A 1 340 ? 48.818 11.366 26.077 1.00 24.49 ? 336 VAL A N 1 ATOM 2611 C CA . VAL A 1 340 ? 48.409 11.558 27.459 1.00 24.38 ? 336 VAL A CA 1 ATOM 2612 C C . VAL A 1 340 ? 46.953 11.073 27.707 1.00 24.70 ? 336 VAL A C 1 ATOM 2613 O O . VAL A 1 340 ? 46.620 10.482 28.747 1.00 25.78 ? 336 VAL A O 1 ATOM 2614 C CB . VAL A 1 340 ? 48.573 13.017 27.825 1.00 25.64 ? 336 VAL A CB 1 ATOM 2615 C CG1 . VAL A 1 340 ? 47.889 13.341 29.132 1.00 25.54 ? 336 VAL A CG1 1 ATOM 2616 C CG2 . VAL A 1 340 ? 50.080 13.392 27.840 1.00 25.15 ? 336 VAL A CG2 1 ATOM 2617 N N . ILE A 1 341 ? 46.097 11.284 26.711 1.00 23.72 ? 337 ILE A N 1 ATOM 2618 C CA . ILE A 1 341 ? 44.737 10.708 26.739 1.00 22.64 ? 337 ILE A CA 1 ATOM 2619 C C . ILE A 1 341 ? 44.647 9.716 25.563 1.00 21.87 ? 337 ILE A C 1 ATOM 2620 O O . ILE A 1 341 ? 44.945 10.104 24.393 1.00 23.04 ? 337 ILE A O 1 ATOM 2621 C CB . ILE A 1 341 ? 43.678 11.854 26.641 1.00 21.61 ? 337 ILE A CB 1 ATOM 2622 C CG1 . ILE A 1 341 ? 43.704 12.720 27.910 1.00 22.60 ? 337 ILE A CG1 1 ATOM 2623 C CG2 . ILE A 1 341 ? 42.274 11.287 26.345 1.00 22.49 ? 337 ILE A CG2 1 ATOM 2624 C CD1 . ILE A 1 341 ? 42.944 14.072 27.803 1.00 23.59 ? 337 ILE A CD1 1 ATOM 2625 N N . PRO A 1 342 ? 44.254 8.442 25.822 1.00 22.76 ? 338 PRO A N 1 ATOM 2626 C CA . PRO A 1 342 ? 44.260 7.504 24.700 1.00 22.57 ? 338 PRO A CA 1 ATOM 2627 C C . PRO A 1 342 ? 43.074 7.678 23.778 1.00 22.90 ? 338 PRO A C 1 ATOM 2628 O O . PRO A 1 342 ? 42.010 8.163 24.209 1.00 20.66 ? 338 PRO A O 1 ATOM 2629 C CB . PRO A 1 342 ? 44.199 6.145 25.370 1.00 23.86 ? 338 PRO A CB 1 ATOM 2630 C CG . PRO A 1 342 ? 43.486 6.427 26.659 1.00 23.55 ? 338 PRO A CG 1 ATOM 2631 C CD . PRO A 1 342 ? 43.926 7.762 27.098 1.00 21.29 ? 338 PRO A CD 1 ATOM 2632 N N . MET A 1 343 ? 43.245 7.310 22.528 1.00 22.04 ? 339 MET A N 1 ATOM 2633 C CA . MET A 1 343 ? 42.119 7.300 21.582 1.00 22.36 ? 339 MET A CA 1 ATOM 2634 C C . MET A 1 343 ? 40.914 6.493 22.076 1.00 23.74 ? 339 MET A C 1 ATOM 2635 O O . MET A 1 343 ? 39.770 6.838 21.727 1.00 23.45 ? 339 MET A O 1 ATOM 2636 C CB . MET A 1 343 ? 42.564 6.811 20.187 1.00 23.22 ? 339 MET A CB 1 ATOM 2637 C CG . MET A 1 343 ? 41.482 6.926 19.071 1.00 27.04 ? 339 MET A CG 1 ATOM 2638 S SD . MET A 1 343 ? 40.992 8.649 18.604 1.00 32.83 ? 339 MET A SD 1 ATOM 2639 C CE . MET A 1 343 ? 42.286 9.610 19.250 1.00 22.69 ? 339 MET A CE 1 ATOM 2640 N N . SER A 1 344 ? 41.138 5.419 22.828 1.00 21.97 ? 340 SER A N 1 ATOM 2641 C CA . SER A 1 344 ? 40.043 4.643 23.384 1.00 22.95 ? 340 SER A CA 1 ATOM 2642 C C . SER A 1 344 ? 39.099 5.530 24.224 1.00 22.12 ? 340 SER A C 1 ATOM 2643 O O . SER A 1 344 ? 37.868 5.307 24.208 1.00 24.06 ? 340 SER A O 1 ATOM 2644 C CB . SER A 1 344 ? 40.547 3.443 24.213 1.00 22.10 ? 340 SER A CB 1 ATOM 2645 O OG . SER A 1 344 ? 41.288 3.883 25.312 1.00 24.59 ? 340 SER A OG 1 ATOM 2646 N N . ARG A 1 345 ? 39.657 6.521 24.907 1.00 21.58 ? 341 ARG A N 1 ATOM 2647 C CA . ARG A 1 345 ? 38.847 7.407 25.801 1.00 20.26 ? 341 ARG A CA 1 ATOM 2648 C C . ARG A 1 345 ? 38.001 8.344 24.941 1.00 19.96 ? 341 ARG A C 1 ATOM 2649 O O . ARG A 1 345 ? 36.755 8.466 25.172 1.00 19.78 ? 341 ARG A O 1 ATOM 2650 C CB . ARG A 1 345 ? 39.750 8.172 26.783 1.00 19.59 ? 341 ARG A CB 1 ATOM 2651 C CG . ARG A 1 345 ? 39.060 9.082 27.842 1.00 20.12 ? 341 ARG A CG 1 ATOM 2652 C CD . ARG A 1 345 ? 38.200 8.290 28.864 1.00 19.64 ? 341 ARG A CD 1 ATOM 2653 N NE . ARG A 1 345 ? 36.826 8.049 28.417 1.00 20.76 ? 341 ARG A NE 1 ATOM 2654 C CZ . ARG A 1 345 ? 35.898 9.029 28.366 1.00 18.60 ? 341 ARG A CZ 1 ATOM 2655 N NH1 . ARG A 1 345 ? 36.201 10.256 28.738 1.00 18.65 ? 341 ARG A NH1 1 ATOM 2656 N NH2 . ARG A 1 345 ? 34.679 8.742 27.938 1.00 20.32 ? 341 ARG A NH2 1 ATOM 2657 N N . ILE A 1 346 ? 38.616 8.944 23.923 1.00 18.87 ? 342 ILE A N 1 ATOM 2658 C CA . ILE A 1 346 ? 37.875 9.757 22.956 1.00 18.27 ? 342 ILE A CA 1 ATOM 2659 C C . ILE A 1 346 ? 36.778 8.948 22.295 1.00 18.40 ? 342 ILE A C 1 ATOM 2660 O O . ILE A 1 346 ? 35.627 9.407 22.146 1.00 19.05 ? 342 ILE A O 1 ATOM 2661 C CB . ILE A 1 346 ? 38.859 10.378 21.874 1.00 19.61 ? 342 ILE A CB 1 ATOM 2662 C CG1 . ILE A 1 346 ? 39.967 11.203 22.531 1.00 18.61 ? 342 ILE A CG1 1 ATOM 2663 C CG2 . ILE A 1 346 ? 38.106 11.190 20.842 1.00 18.60 ? 342 ILE A CG2 1 ATOM 2664 C CD1 . ILE A 1 346 ? 39.546 12.384 23.407 1.00 18.95 ? 342 ILE A CD1 1 ATOM 2665 N N . ASP A 1 347 ? 37.097 7.741 21.838 1.00 18.01 ? 343 ASP A N 1 ATOM 2666 C CA . ASP A 1 347 ? 36.099 6.962 21.105 1.00 17.09 ? 343 ASP A CA 1 ATOM 2667 C C . ASP A 1 347 ? 34.922 6.568 22.007 1.00 17.65 ? 343 ASP A C 1 ATOM 2668 O O . ASP A 1 347 ? 33.792 6.508 21.528 1.00 19.26 ? 343 ASP A O 1 ATOM 2669 C CB . ASP A 1 347 ? 36.765 5.690 20.518 1.00 18.89 ? 343 ASP A CB 1 ATOM 2670 C CG . ASP A 1 347 ? 37.641 6.005 19.319 1.00 21.47 ? 343 ASP A CG 1 ATOM 2671 O OD1 . ASP A 1 347 ? 37.659 7.170 18.853 1.00 20.15 ? 343 ASP A OD1 1 ATOM 2672 O OD2 . ASP A 1 347 ? 38.316 5.034 18.837 1.00 22.86 ? 343 ASP A OD2 1 ATOM 2673 N N . ASP A 1 348 ? 35.197 6.286 23.275 1.00 17.56 ? 344 ASP A N 1 ATOM 2674 C CA . ASP A 1 348 ? 34.115 6.004 24.247 1.00 17.34 ? 344 ASP A CA 1 ATOM 2675 C C . ASP A 1 348 ? 33.189 7.208 24.392 1.00 18.86 ? 344 ASP A C 1 ATOM 2676 O O . ASP A 1 348 ? 31.943 7.071 24.310 1.00 17.57 ? 344 ASP A O 1 ATOM 2677 C CB . ASP A 1 348 ? 34.676 5.595 25.617 1.00 18.40 ? 344 ASP A CB 1 ATOM 2678 C CG . ASP A 1 348 ? 33.570 5.429 26.666 1.00 18.62 ? 344 ASP A CG 1 ATOM 2679 O OD1 . ASP A 1 348 ? 32.721 4.542 26.483 1.00 22.07 ? 344 ASP A OD1 1 ATOM 2680 O OD2 . ASP A 1 348 ? 33.628 6.180 27.644 1.00 23.06 ? 344 ASP A OD2 1 ATOM 2681 N N . ALA A 1 349 ? 33.793 8.364 24.571 1.00 17.91 ? 345 ALA A N 1 ATOM 2682 C CA . ALA A 1 349 ? 33.028 9.628 24.748 1.00 16.72 ? 345 ALA A CA 1 ATOM 2683 C C . ALA A 1 349 ? 32.122 9.851 23.517 1.00 16.69 ? 345 ALA A C 1 ATOM 2684 O O . ALA A 1 349 ? 30.909 10.116 23.634 1.00 16.39 ? 345 ALA A O 1 ATOM 2685 C CB . ALA A 1 349 ? 33.958 10.819 24.944 1.00 17.27 ? 345 ALA A CB 1 ATOM 2686 N N . VAL A 1 350 ? 32.700 9.739 22.326 1.00 16.10 ? 346 VAL A N 1 ATOM 2687 C CA . VAL A 1 350 ? 31.942 10.006 21.110 1.00 16.35 ? 346 VAL A CA 1 ATOM 2688 C C . VAL A 1 350 ? 30.905 8.920 20.870 1.00 16.88 ? 346 VAL A C 1 ATOM 2689 O O . VAL A 1 350 ? 29.790 9.200 20.396 1.00 17.75 ? 346 VAL A O 1 ATOM 2690 C CB . VAL A 1 350 ? 32.939 10.186 19.904 1.00 16.06 ? 346 VAL A CB 1 ATOM 2691 C CG1 . VAL A 1 350 ? 32.130 10.403 18.600 1.00 16.85 ? 346 VAL A CG1 1 ATOM 2692 C CG2 . VAL A 1 350 ? 33.854 11.377 20.175 1.00 17.32 ? 346 VAL A CG2 1 ATOM 2693 N N . THR A 1 351 ? 31.234 7.655 21.181 1.00 16.42 ? 347 THR A N 1 ATOM 2694 C CA . THR A 1 351 ? 30.248 6.582 21.089 1.00 17.24 ? 347 THR A CA 1 ATOM 2695 C C . THR A 1 351 ? 29.002 6.931 21.908 1.00 16.86 ? 347 THR A C 1 ATOM 2696 O O . THR A 1 351 ? 27.918 6.766 21.413 1.00 17.43 ? 347 THR A O 1 ATOM 2697 C CB . THR A 1 351 ? 30.841 5.248 21.634 1.00 17.57 ? 347 THR A CB 1 ATOM 2698 O OG1 . THR A 1 351 ? 31.766 4.771 20.631 1.00 19.41 ? 347 THR A OG1 1 ATOM 2699 C CG2 . THR A 1 351 ? 29.797 4.174 21.773 1.00 19.36 ? 347 THR A CG2 1 ATOM 2700 N N . ARG A 1 352 ? 29.212 7.391 23.122 1.00 16.66 ? 348 ARG A N 1 ATOM 2701 C CA . ARG A 1 352 ? 28.066 7.721 24.038 1.00 16.59 ? 348 ARG A CA 1 ATOM 2702 C C . ARG A 1 352 ? 27.295 8.942 23.546 1.00 17.24 ? 348 ARG A C 1 ATOM 2703 O O . ARG A 1 352 ? 26.031 8.904 23.543 1.00 16.57 ? 348 ARG A O 1 ATOM 2704 C CB . ARG A 1 352 ? 28.617 7.997 25.424 1.00 15.34 ? 348 ARG A CB 1 ATOM 2705 C CG . ARG A 1 352 ? 29.199 6.702 26.083 1.00 17.01 ? 348 ARG A CG 1 ATOM 2706 C CD . ARG A 1 352 ? 30.080 7.025 27.266 1.00 16.20 ? 348 ARG A CD 1 ATOM 2707 N NE . ARG A 1 352 ? 30.380 5.740 27.901 1.00 19.70 ? 348 ARG A NE 1 ATOM 2708 C CZ . ARG A 1 352 ? 29.587 5.124 28.769 1.00 22.72 ? 348 ARG A CZ 1 ATOM 2709 N NH1 . ARG A 1 352 ? 28.427 5.715 29.168 1.00 18.25 ? 348 ARG A NH1 1 ATOM 2710 N NH2 . ARG A 1 352 ? 29.940 3.910 29.231 1.00 22.23 ? 348 ARG A NH2 1 ATOM 2711 N N . ILE A 1 353 ? 27.995 9.962 23.033 1.00 15.53 ? 349 ILE A N 1 ATOM 2712 C CA . ILE A 1 353 ? 27.281 11.151 22.520 1.00 15.19 ? 349 ILE A CA 1 ATOM 2713 C C . ILE A 1 353 ? 26.473 10.758 21.288 1.00 15.92 ? 349 ILE A C 1 ATOM 2714 O O . ILE A 1 353 ? 25.263 11.106 21.148 1.00 15.55 ? 349 ILE A O 1 ATOM 2715 C CB . ILE A 1 353 ? 28.289 12.303 22.249 1.00 16.63 ? 349 ILE A CB 1 ATOM 2716 C CG1 . ILE A 1 353 ? 28.891 12.778 23.583 1.00 15.32 ? 349 ILE A CG1 1 ATOM 2717 C CG2 . ILE A 1 353 ? 27.649 13.431 21.425 1.00 15.94 ? 349 ILE A CG2 1 ATOM 2718 C CD1 . ILE A 1 353 ? 30.155 13.681 23.363 1.00 17.03 ? 349 ILE A CD1 1 ATOM 2719 N N . LEU A 1 354 ? 27.103 10.028 20.347 1.00 15.83 ? 350 LEU A N 1 ATOM 2720 C CA . LEU A 1 354 ? 26.372 9.598 19.180 1.00 15.68 ? 350 LEU A CA 1 ATOM 2721 C C . LEU A 1 354 ? 25.195 8.645 19.513 1.00 16.02 ? 350 LEU A C 1 ATOM 2722 O O . LEU A 1 354 ? 24.136 8.722 18.870 1.00 16.79 ? 350 LEU A O 1 ATOM 2723 C CB . LEU A 1 354 ? 27.329 8.904 18.159 1.00 14.71 ? 350 LEU A CB 1 ATOM 2724 C CG . LEU A 1 354 ? 28.391 9.853 17.584 1.00 15.62 ? 350 LEU A CG 1 ATOM 2725 C CD1 . LEU A 1 354 ? 29.224 8.950 16.605 1.00 17.21 ? 350 LEU A CD1 1 ATOM 2726 C CD2 . LEU A 1 354 ? 27.809 11.056 16.827 1.00 16.84 ? 350 LEU A CD2 1 ATOM 2727 N N . ARG A 1 355 ? 25.434 7.754 20.486 1.00 16.83 ? 351 ARG A N 1 ATOM 2728 C CA . ARG A 1 355 ? 24.368 6.810 20.881 1.00 17.58 ? 351 ARG A CA 1 ATOM 2729 C C . ARG A 1 355 ? 23.112 7.606 21.294 1.00 16.15 ? 351 ARG A C 1 ATOM 2730 O O . ARG A 1 355 ? 21.994 7.273 20.855 1.00 16.71 ? 351 ARG A O 1 ATOM 2731 C CB . ARG A 1 355 ? 24.814 5.876 21.985 1.00 17.30 ? 351 ARG A CB 1 ATOM 2732 C CG . ARG A 1 355 ? 23.685 4.951 22.474 1.00 17.13 ? 351 ARG A CG 1 ATOM 2733 C CD . ARG A 1 355 ? 24.179 4.064 23.624 1.00 18.16 ? 351 ARG A CD 1 ATOM 2734 N NE . ARG A 1 355 ? 25.249 3.124 23.139 1.00 19.32 ? 351 ARG A NE 1 ATOM 2735 C CZ . ARG A 1 355 ? 26.477 3.028 23.642 1.00 21.39 ? 351 ARG A CZ 1 ATOM 2736 N NH1 . ARG A 1 355 ? 26.880 3.748 24.672 1.00 20.38 ? 351 ARG A NH1 1 ATOM 2737 N NH2 . ARG A 1 355 ? 27.336 2.134 23.089 1.00 22.26 ? 351 ARG A NH2 1 ATOM 2738 N N . VAL A 1 356 ? 23.308 8.680 22.067 1.00 15.55 ? 352 VAL A N 1 ATOM 2739 C CA . VAL A 1 356 ? 22.121 9.452 22.518 1.00 15.32 ? 352 VAL A CA 1 ATOM 2740 C C . VAL A 1 356 ? 21.485 10.152 21.321 1.00 15.40 ? 352 VAL A C 1 ATOM 2741 O O . VAL A 1 356 ? 20.241 10.126 21.130 1.00 14.63 ? 352 VAL A O 1 ATOM 2742 C CB . VAL A 1 356 ? 22.507 10.462 23.602 1.00 14.38 ? 352 VAL A CB 1 ATOM 2743 C CG1 . VAL A 1 356 ? 21.338 11.473 23.846 1.00 16.88 ? 352 VAL A CG1 1 ATOM 2744 C CG2 . VAL A 1 356 ? 22.906 9.752 24.885 1.00 15.70 ? 352 VAL A CG2 1 ATOM 2745 N N . LYS A 1 357 ? 22.305 10.746 20.437 1.00 14.58 ? 353 LYS A N 1 ATOM 2746 C CA . LYS A 1 357 ? 21.776 11.463 19.279 1.00 12.97 ? 353 LYS A CA 1 ATOM 2747 C C . LYS A 1 357 ? 20.982 10.534 18.352 1.00 14.10 ? 353 LYS A C 1 ATOM 2748 O O . LYS A 1 357 ? 19.879 10.877 17.899 1.00 14.97 ? 353 LYS A O 1 ATOM 2749 C CB . LYS A 1 357 ? 22.937 12.161 18.502 1.00 14.24 ? 353 LYS A CB 1 ATOM 2750 C CG . LYS A 1 357 ? 23.497 13.350 19.285 1.00 13.28 ? 353 LYS A CG 1 ATOM 2751 C CD . LYS A 1 357 ? 24.501 14.091 18.406 1.00 14.11 ? 353 LYS A CD 1 ATOM 2752 C CE . LYS A 1 357 ? 24.956 15.384 19.132 1.00 14.34 ? 353 LYS A CE 1 ATOM 2753 N NZ . LYS A 1 357 ? 25.972 16.125 18.238 1.00 13.86 ? 353 LYS A NZ 1 ATOM 2754 N N . PHE A 1 358 ? 21.539 9.348 18.070 1.00 15.23 ? 354 PHE A N 1 ATOM 2755 C CA . PHE A 1 358 ? 20.821 8.464 17.168 1.00 15.28 ? 354 PHE A CA 1 ATOM 2756 C C . PHE A 1 358 ? 19.538 7.921 17.839 1.00 14.97 ? 354 PHE A C 1 ATOM 2757 O O . PHE A 1 358 ? 18.478 7.867 17.168 1.00 16.73 ? 354 PHE A O 1 ATOM 2758 C CB . PHE A 1 358 ? 21.720 7.272 16.799 1.00 15.62 ? 354 PHE A CB 1 ATOM 2759 C CG . PHE A 1 358 ? 22.701 7.572 15.687 1.00 15.76 ? 354 PHE A CG 1 ATOM 2760 C CD1 . PHE A 1 358 ? 22.251 7.891 14.396 1.00 17.03 ? 354 PHE A CD1 1 ATOM 2761 C CD2 . PHE A 1 358 ? 24.086 7.471 15.930 1.00 15.60 ? 354 PHE A CD2 1 ATOM 2762 C CE1 . PHE A 1 358 ? 23.174 8.175 13.316 1.00 18.05 ? 354 PHE A CE1 1 ATOM 2763 C CE2 . PHE A 1 358 ? 25.023 7.762 14.873 1.00 16.85 ? 354 PHE A CE2 1 ATOM 2764 C CZ . PHE A 1 358 ? 24.559 8.091 13.588 1.00 16.20 ? 354 PHE A CZ 1 ATOM 2765 N N . THR A 1 359 ? 19.678 7.557 19.117 1.00 16.99 ? 355 THR A N 1 ATOM 2766 C CA . THR A 1 359 ? 18.569 6.918 19.843 1.00 17.52 ? 355 THR A CA 1 ATOM 2767 C C . THR A 1 359 ? 17.379 7.858 19.866 1.00 17.77 ? 355 THR A C 1 ATOM 2768 O O . THR A 1 359 ? 16.246 7.404 19.661 1.00 17.66 ? 355 THR A O 1 ATOM 2769 C CB . THR A 1 359 ? 18.971 6.591 21.250 1.00 17.64 ? 355 THR A CB 1 ATOM 2770 O OG1 . THR A 1 359 ? 20.002 5.589 21.223 1.00 18.50 ? 355 THR A OG1 1 ATOM 2771 C CG2 . THR A 1 359 ? 17.785 6.052 22.097 1.00 18.52 ? 355 THR A CG2 1 ATOM 2772 N N . MET A 1 360 ? 17.632 9.166 20.058 1.00 17.01 ? 356 MET A N 1 ATOM 2773 C CA . MET A 1 360 ? 16.533 10.138 20.202 1.00 16.02 ? 356 MET A CA 1 ATOM 2774 C C . MET A 1 360 ? 15.908 10.587 18.887 1.00 17.29 ? 356 MET A C 1 ATOM 2775 O O . MET A 1 360 ? 14.927 11.369 18.872 1.00 19.61 ? 356 MET A O 1 ATOM 2776 C CB . MET A 1 360 ? 17.028 11.359 20.992 1.00 15.96 ? 356 MET A CB 1 ATOM 2777 C CG . MET A 1 360 ? 17.939 12.321 20.181 1.00 16.23 ? 356 MET A CG 1 ATOM 2778 S SD . MET A 1 360 ? 18.733 13.490 21.298 1.00 16.55 ? 356 MET A SD 1 ATOM 2779 C CE . MET A 1 360 ? 17.315 14.579 21.710 1.00 18.41 ? 356 MET A CE 1 ATOM 2780 N N . GLY A 1 361 ? 16.468 10.127 17.758 1.00 16.35 ? 357 GLY A N 1 ATOM 2781 C CA . GLY A 1 361 ? 15.958 10.484 16.458 1.00 17.17 ? 357 GLY A CA 1 ATOM 2782 C C . GLY A 1 361 ? 16.512 11.765 15.858 1.00 16.73 ? 357 GLY A C 1 ATOM 2783 O O . GLY A 1 361 ? 15.970 12.288 14.897 1.00 18.50 ? 357 GLY A O 1 ATOM 2784 N N . LEU A 1 362 ? 17.621 12.273 16.429 1.00 15.84 ? 358 LEU A N 1 ATOM 2785 C CA . LEU A 1 362 ? 18.095 13.600 16.024 1.00 14.60 ? 358 LEU A CA 1 ATOM 2786 C C . LEU A 1 362 ? 18.594 13.641 14.558 1.00 15.15 ? 358 LEU A C 1 ATOM 2787 O O . LEU A 1 362 ? 18.485 14.671 13.919 1.00 15.78 ? 358 LEU A O 1 ATOM 2788 C CB . LEU A 1 362 ? 19.227 14.014 16.977 1.00 14.31 ? 358 LEU A CB 1 ATOM 2789 C CG . LEU A 1 362 ? 19.661 15.466 16.910 1.00 15.00 ? 358 LEU A CG 1 ATOM 2790 C CD1 . LEU A 1 362 ? 18.553 16.455 17.363 1.00 17.15 ? 358 LEU A CD1 1 ATOM 2791 C CD2 . LEU A 1 362 ? 20.887 15.678 17.822 1.00 17.01 ? 358 LEU A CD2 1 ATOM 2792 N N . PHE A 1 363 ? 19.124 12.513 14.072 1.00 16.98 ? 359 PHE A N 1 ATOM 2793 C CA . PHE A 1 363 ? 19.522 12.478 12.680 1.00 16.97 ? 359 PHE A CA 1 ATOM 2794 C C . PHE A 1 363 ? 18.331 12.453 11.722 1.00 17.74 ? 359 PHE A C 1 ATOM 2795 O O . PHE A 1 363 ? 18.459 12.858 10.560 1.00 19.44 ? 359 PHE A O 1 ATOM 2796 C CB . PHE A 1 363 ? 20.405 11.254 12.402 1.00 17.48 ? 359 PHE A CB 1 ATOM 2797 C CG . PHE A 1 363 ? 21.830 11.397 12.894 1.00 17.95 ? 359 PHE A CG 1 ATOM 2798 C CD1 . PHE A 1 363 ? 22.150 11.297 14.264 1.00 16.45 ? 359 PHE A CD1 1 ATOM 2799 C CD2 . PHE A 1 363 ? 22.857 11.562 11.971 1.00 19.31 ? 359 PHE A CD2 1 ATOM 2800 C CE1 . PHE A 1 363 ? 23.472 11.362 14.729 1.00 17.54 ? 359 PHE A CE1 1 ATOM 2801 C CE2 . PHE A 1 363 ? 24.233 11.646 12.440 1.00 17.40 ? 359 PHE A CE2 1 ATOM 2802 C CZ . PHE A 1 363 ? 24.521 11.577 13.793 1.00 16.63 ? 359 PHE A CZ 1 ATOM 2803 N N . GLU A 1 364 ? 17.197 11.961 12.230 1.00 18.11 ? 360 GLU A N 1 ATOM 2804 C CA . GLU A 1 364 ? 15.936 11.929 11.416 1.00 18.56 ? 360 GLU A CA 1 ATOM 2805 C C . GLU A 1 364 ? 15.144 13.214 11.511 1.00 18.70 ? 360 GLU A C 1 ATOM 2806 O O . GLU A 1 364 ? 14.505 13.606 10.513 1.00 19.43 ? 360 GLU A O 1 ATOM 2807 C CB . GLU A 1 364 ? 15.061 10.759 11.804 1.00 18.30 ? 360 GLU A CB 1 ATOM 2808 C CG . GLU A 1 364 ? 15.541 9.411 11.144 1.00 19.26 ? 360 GLU A CG 1 ATOM 2809 C CD . GLU A 1 364 ? 16.971 9.010 11.561 1.00 17.73 ? 360 GLU A CD 1 ATOM 2810 O OE1 . GLU A 1 364 ? 17.141 8.563 12.704 1.00 20.36 ? 360 GLU A OE1 1 ATOM 2811 O OE2 . GLU A 1 364 ? 17.885 9.189 10.728 1.00 21.74 ? 360 GLU A OE2 1 ATOM 2812 N N . ASN A 1 365 ? 15.226 13.915 12.656 1.00 17.42 ? 361 ASN A N 1 ATOM 2813 C CA . ASN A 1 365 ? 14.540 15.197 12.833 1.00 18.55 ? 361 ASN A CA 1 ATOM 2814 C C . ASN A 1 365 ? 15.446 16.263 13.450 1.00 18.28 ? 361 ASN A C 1 ATOM 2815 O O . ASN A 1 365 ? 15.315 16.610 14.640 1.00 18.09 ? 361 ASN A O 1 ATOM 2816 C CB . ASN A 1 365 ? 13.230 15.019 13.651 1.00 18.11 ? 361 ASN A CB 1 ATOM 2817 C CG . ASN A 1 365 ? 12.163 14.309 12.828 1.00 21.40 ? 361 ASN A CG 1 ATOM 2818 O OD1 . ASN A 1 365 ? 11.476 14.931 12.000 1.00 26.45 ? 361 ASN A OD1 1 ATOM 2819 N ND2 . ASN A 1 365 ? 12.069 13.037 13.006 1.00 20.31 ? 361 ASN A ND2 1 ATOM 2820 N N . PRO A 1 366 ? 16.419 16.743 12.669 1.00 17.38 ? 362 PRO A N 1 ATOM 2821 C CA . PRO A 1 366 ? 17.371 17.710 13.246 1.00 16.60 ? 362 PRO A CA 1 ATOM 2822 C C . PRO A 1 366 ? 16.792 19.106 13.403 1.00 16.90 ? 362 PRO A C 1 ATOM 2823 O O . PRO A 1 366 ? 17.350 19.901 14.129 1.00 16.10 ? 362 PRO A O 1 ATOM 2824 C CB . PRO A 1 366 ? 18.530 17.709 12.238 1.00 17.51 ? 362 PRO A CB 1 ATOM 2825 C CG . PRO A 1 366 ? 17.916 17.188 10.973 1.00 19.88 ? 362 PRO A CG 1 ATOM 2826 C CD . PRO A 1 366 ? 16.870 16.231 11.352 1.00 18.32 ? 362 PRO A CD 1 ATOM 2827 N N . TYR A 1 367 ? 15.654 19.393 12.740 1.00 15.83 ? 363 TYR A N 1 ATOM 2828 C CA . TYR A 1 367 ? 15.120 20.736 12.712 1.00 15.80 ? 363 TYR A CA 1 ATOM 2829 C C . TYR A 1 367 ? 13.789 20.779 13.472 1.00 15.57 ? 363 TYR A C 1 ATOM 2830 O O . TYR A 1 367 ? 13.154 19.748 13.739 1.00 18.52 ? 363 TYR A O 1 ATOM 2831 C CB . TYR A 1 367 ? 14.895 21.226 11.258 1.00 16.79 ? 363 TYR A CB 1 ATOM 2832 C CG . TYR A 1 367 ? 16.189 21.301 10.497 1.00 18.42 ? 363 TYR A CG 1 ATOM 2833 C CD1 . TYR A 1 367 ? 17.100 22.305 10.779 1.00 19.57 ? 363 TYR A CD1 1 ATOM 2834 C CD2 . TYR A 1 367 ? 16.474 20.375 9.504 1.00 18.68 ? 363 TYR A CD2 1 ATOM 2835 C CE1 . TYR A 1 367 ? 18.299 22.425 10.086 1.00 21.16 ? 363 TYR A CE1 1 ATOM 2836 C CE2 . TYR A 1 367 ? 17.712 20.452 8.795 1.00 19.67 ? 363 TYR A CE2 1 ATOM 2837 C CZ . TYR A 1 367 ? 18.594 21.484 9.102 1.00 22.36 ? 363 TYR A CZ 1 ATOM 2838 O OH . TYR A 1 367 ? 19.808 21.638 8.425 1.00 23.05 ? 363 TYR A OH 1 ATOM 2839 N N . ALA A 1 368 ? 13.463 22.001 13.888 1.00 17.38 ? 364 ALA A N 1 ATOM 2840 C CA . ALA A 1 368 ? 12.261 22.231 14.690 1.00 16.62 ? 364 ALA A CA 1 ATOM 2841 C C . ALA A 1 368 ? 10.989 22.005 13.879 1.00 17.73 ? 364 ALA A C 1 ATOM 2842 O O . ALA A 1 368 ? 10.965 22.096 12.611 1.00 17.66 ? 364 ALA A O 1 ATOM 2843 C CB . ALA A 1 368 ? 12.275 23.658 15.221 1.00 16.46 ? 364 ALA A CB 1 ATOM 2844 N N . ASP A 1 369 ? 9.905 21.752 14.621 1.00 17.22 ? 365 ASP A N 1 ATOM 2845 C CA . ASP A 1 369 ? 8.570 21.590 14.017 1.00 17.65 ? 365 ASP A CA 1 ATOM 2846 C C . ASP A 1 369 ? 7.755 22.855 14.269 1.00 18.34 ? 365 ASP A C 1 ATOM 2847 O O . ASP A 1 369 ? 7.368 23.119 15.416 1.00 18.09 ? 365 ASP A O 1 ATOM 2848 C CB . ASP A 1 369 ? 7.889 20.369 14.648 1.00 18.21 ? 365 ASP A CB 1 ATOM 2849 C CG . ASP A 1 369 ? 6.524 20.090 14.060 1.00 19.41 ? 365 ASP A CG 1 ATOM 2850 O OD1 . ASP A 1 369 ? 6.063 20.889 13.217 1.00 20.73 ? 365 ASP A OD1 1 ATOM 2851 O OD2 . ASP A 1 369 ? 5.936 19.065 14.516 1.00 23.46 ? 365 ASP A OD2 1 ATOM 2852 N N . PRO A 1 370 ? 7.523 23.670 13.245 1.00 18.39 ? 366 PRO A N 1 ATOM 2853 C CA . PRO A 1 370 ? 6.751 24.904 13.449 1.00 20.24 ? 366 PRO A CA 1 ATOM 2854 C C . PRO A 1 370 ? 5.361 24.670 14.029 1.00 20.03 ? 366 PRO A C 1 ATOM 2855 O O . PRO A 1 370 ? 4.877 25.554 14.718 1.00 20.06 ? 366 PRO A O 1 ATOM 2856 C CB . PRO A 1 370 ? 6.659 25.537 12.040 1.00 19.80 ? 366 PRO A CB 1 ATOM 2857 C CG . PRO A 1 370 ? 6.888 24.374 11.119 1.00 23.62 ? 366 PRO A CG 1 ATOM 2858 C CD . PRO A 1 370 ? 7.909 23.505 11.819 1.00 20.20 ? 366 PRO A CD 1 ATOM 2859 N N . ALA A 1 371 ? 4.767 23.489 13.822 1.00 19.22 ? 367 ALA A N 1 ATOM 2860 C CA . ALA A 1 371 ? 3.442 23.237 14.385 1.00 21.18 ? 367 ALA A CA 1 ATOM 2861 C C . ALA A 1 371 ? 3.490 23.085 15.897 1.00 20.25 ? 367 ALA A C 1 ATOM 2862 O O . ALA A 1 371 ? 2.447 23.164 16.571 1.00 22.53 ? 367 ALA A O 1 ATOM 2863 C CB . ALA A 1 371 ? 2.812 22.014 13.733 1.00 21.50 ? 367 ALA A CB 1 ATOM 2864 N N . MET A 1 372 ? 4.691 22.930 16.470 1.00 17.99 ? 368 MET A N 1 ATOM 2865 C CA . MET A 1 372 ? 4.802 22.768 17.931 1.00 18.35 ? 368 MET A CA 1 ATOM 2866 C C . MET A 1 372 ? 4.896 24.128 18.642 1.00 17.07 ? 368 MET A C 1 ATOM 2867 O O . MET A 1 372 ? 4.762 24.160 19.868 1.00 17.96 ? 368 MET A O 1 ATOM 2868 C CB . MET A 1 372 ? 6.045 21.927 18.344 1.00 18.01 ? 368 MET A CB 1 ATOM 2869 C CG . MET A 1 372 ? 6.026 20.464 17.897 1.00 21.41 ? 368 MET A CG 1 ATOM 2870 S SD . MET A 1 372 ? 4.781 19.591 18.873 1.00 28.88 ? 368 MET A SD 1 ATOM 2871 C CE . MET A 1 372 ? 5.771 19.321 20.354 1.00 26.19 ? 368 MET A CE 1 ATOM 2872 N N . ALA A 1 373 ? 5.121 25.222 17.927 1.00 16.71 ? 369 ALA A N 1 ATOM 2873 C CA . ALA A 1 373 ? 5.250 26.554 18.563 1.00 16.59 ? 369 ALA A CA 1 ATOM 2874 C C . ALA A 1 373 ? 4.085 26.870 19.486 1.00 18.46 ? 369 ALA A C 1 ATOM 2875 O O . ALA A 1 373 ? 4.296 27.394 20.593 1.00 19.33 ? 369 ALA A O 1 ATOM 2876 C CB . ALA A 1 373 ? 5.512 27.659 17.565 1.00 18.13 ? 369 ALA A CB 1 ATOM 2877 N N . GLU A 1 374 ? 2.879 26.516 19.059 1.00 20.15 ? 370 GLU A N 1 ATOM 2878 C CA . GLU A 1 374 ? 1.675 26.856 19.826 1.00 21.76 ? 370 GLU A CA 1 ATOM 2879 C C . GLU A 1 374 ? 1.528 26.068 21.118 1.00 21.52 ? 370 GLU A C 1 ATOM 2880 O O . GLU A 1 374 ? 0.610 26.347 21.924 1.00 21.97 ? 370 GLU A O 1 ATOM 2881 C CB . GLU A 1 374 ? 0.432 26.752 18.918 1.00 22.48 ? 370 GLU A CB 1 ATOM 2882 C CG . GLU A 1 374 ? 0.157 25.342 18.422 1.00 29.00 ? 370 GLU A CG 1 ATOM 2883 C CD . GLU A 1 374 ? -0.796 25.325 17.200 1.00 39.13 ? 370 GLU A CD 1 ATOM 2884 O OE1 . GLU A 1 374 ? -1.946 24.928 17.425 1.00 40.80 ? 370 GLU A OE1 1 ATOM 2885 O OE2 . GLU A 1 374 ? -0.382 25.678 16.035 1.00 44.84 ? 370 GLU A OE2 1 ATOM 2886 N N . GLN A 1 375 ? 2.397 25.090 21.382 1.00 19.02 ? 371 GLN A N 1 ATOM 2887 C CA . GLN A 1 375 ? 2.368 24.363 22.668 1.00 17.90 ? 371 GLN A CA 1 ATOM 2888 C C . GLN A 1 375 ? 2.812 25.259 23.839 1.00 18.54 ? 371 GLN A C 1 ATOM 2889 O O . GLN A 1 375 ? 2.494 24.962 25.005 1.00 17.92 ? 371 GLN A O 1 ATOM 2890 C CB . GLN A 1 375 ? 3.333 23.176 22.651 1.00 17.94 ? 371 GLN A CB 1 ATOM 2891 C CG . GLN A 1 375 ? 2.958 22.063 21.674 1.00 20.08 ? 371 GLN A CG 1 ATOM 2892 C CD . GLN A 1 375 ? 1.782 21.220 22.170 1.00 27.26 ? 371 GLN A CD 1 ATOM 2893 O OE1 . GLN A 1 375 ? 1.535 21.089 23.371 1.00 23.97 ? 371 GLN A OE1 1 ATOM 2894 N NE2 . GLN A 1 375 ? 1.082 20.610 21.229 1.00 33.19 ? 371 GLN A NE2 1 ATOM 2895 N N . LEU A 1 376 ? 3.546 26.352 23.538 1.00 17.13 ? 372 LEU A N 1 ATOM 2896 C CA . LEU A 1 376 ? 4.109 27.193 24.585 1.00 16.98 ? 372 LEU A CA 1 ATOM 2897 C C . LEU A 1 376 ? 2.978 27.895 25.359 1.00 16.43 ? 372 LEU A C 1 ATOM 2898 O O . LEU A 1 376 ? 2.074 28.538 24.774 1.00 17.76 ? 372 LEU A O 1 ATOM 2899 C CB . LEU A 1 376 ? 5.026 28.208 23.927 1.00 16.05 ? 372 LEU A CB 1 ATOM 2900 C CG . LEU A 1 376 ? 5.833 29.048 24.912 1.00 18.20 ? 372 LEU A CG 1 ATOM 2901 C CD1 . LEU A 1 376 ? 6.978 28.193 25.512 1.00 19.28 ? 372 LEU A CD1 1 ATOM 2902 C CD2 . LEU A 1 376 ? 6.424 30.274 24.191 1.00 21.63 ? 372 LEU A CD2 1 ATOM 2903 N N . GLY A 1 377 ? 3.005 27.717 26.674 1.00 14.96 ? 373 GLY A N 1 ATOM 2904 C CA . GLY A 1 377 ? 2.015 28.357 27.553 1.00 15.20 ? 373 GLY A CA 1 ATOM 2905 C C . GLY A 1 377 ? 0.603 27.847 27.383 1.00 15.70 ? 373 GLY A C 1 ATOM 2906 O O . GLY A 1 377 ? -0.332 28.557 27.784 1.00 17.40 ? 373 GLY A O 1 ATOM 2907 N N . LYS A 1 378 ? 0.427 26.646 26.795 1.00 15.41 ? 374 LYS A N 1 ATOM 2908 C CA . LYS A 1 378 ? -0.961 26.185 26.496 1.00 17.43 ? 374 LYS A CA 1 ATOM 2909 C C . LYS A 1 378 ? -1.808 26.091 27.762 1.00 16.61 ? 374 LYS A C 1 ATOM 2910 O O . LYS A 1 378 ? -1.334 25.695 28.809 1.00 15.93 ? 374 LYS A O 1 ATOM 2911 C CB . LYS A 1 378 ? -0.955 24.778 25.838 1.00 18.80 ? 374 LYS A CB 1 ATOM 2912 C CG . LYS A 1 378 ? -1.268 24.787 24.413 1.00 26.30 ? 374 LYS A CG 1 ATOM 2913 C CD . LYS A 1 378 ? -1.189 23.348 23.829 1.00 30.37 ? 374 LYS A CD 1 ATOM 2914 C CE . LYS A 1 378 ? -1.151 22.261 24.898 1.00 31.00 ? 374 LYS A CE 1 ATOM 2915 N NZ . LYS A 1 378 ? -0.990 20.783 24.376 1.00 36.00 ? 374 LYS A NZ 1 ATOM 2916 N N . GLN A 1 379 ? -3.094 26.394 27.617 1.00 16.77 ? 375 GLN A N 1 ATOM 2917 C CA . GLN A 1 379 ? -3.962 26.436 28.799 1.00 17.13 ? 375 GLN A CA 1 ATOM 2918 C C . GLN A 1 379 ? -3.987 25.064 29.498 1.00 16.23 ? 375 GLN A C 1 ATOM 2919 O O . GLN A 1 379 ? -4.018 25.006 30.731 1.00 17.11 ? 375 GLN A O 1 ATOM 2920 C CB . GLN A 1 379 ? -5.372 26.903 28.387 1.00 17.22 ? 375 GLN A CB 1 ATOM 2921 C CG . GLN A 1 379 ? -6.282 27.090 29.621 1.00 20.01 ? 375 GLN A CG 1 ATOM 2922 C CD . GLN A 1 379 ? -5.709 28.177 30.559 1.00 26.68 ? 375 GLN A CD 1 ATOM 2923 O OE1 . GLN A 1 379 ? -5.337 29.257 30.119 1.00 30.48 ? 375 GLN A OE1 1 ATOM 2924 N NE2 . GLN A 1 379 ? -5.572 27.853 31.850 1.00 21.80 ? 375 GLN A NE2 1 ATOM 2925 N N . GLU A 1 380 ? -3.980 23.943 28.791 1.00 16.03 ? 376 GLU A N 1 ATOM 2926 C CA . GLU A 1 380 ? -3.931 22.639 29.441 1.00 16.86 ? 376 GLU A CA 1 ATOM 2927 C C . GLU A 1 380 ? -2.739 22.489 30.396 1.00 14.65 ? 376 GLU A C 1 ATOM 2928 O O . GLU A 1 380 ? -2.824 21.849 31.439 1.00 16.24 ? 376 GLU A O 1 ATOM 2929 C CB . GLU A 1 380 ? -3.867 21.498 28.404 1.00 18.87 ? 376 GLU A CB 1 ATOM 2930 C CG . GLU A 1 380 ? -5.128 21.522 27.449 1.00 24.84 ? 376 GLU A CG 1 ATOM 2931 C CD . GLU A 1 380 ? -5.081 22.452 26.195 1.00 27.89 ? 376 GLU A CD 1 ATOM 2932 O OE1 . GLU A 1 380 ? -4.424 23.511 26.100 1.00 20.42 ? 376 GLU A OE1 1 ATOM 2933 O OE2 . GLU A 1 380 ? -5.808 22.099 25.199 1.00 36.69 ? 376 GLU A OE2 1 ATOM 2934 N N . HIS A 1 381 ? -1.591 23.035 29.975 1.00 14.70 ? 377 HIS A N 1 ATOM 2935 C CA . HIS A 1 381 ? -0.411 22.958 30.810 1.00 14.41 ? 377 HIS A CA 1 ATOM 2936 C C . HIS A 1 381 ? -0.501 23.930 31.987 1.00 12.82 ? 377 HIS A C 1 ATOM 2937 O O . HIS A 1 381 ? 0.012 23.609 33.086 1.00 13.28 ? 377 HIS A O 1 ATOM 2938 C CB . HIS A 1 381 ? 0.793 23.368 29.974 1.00 13.07 ? 377 HIS A CB 1 ATOM 2939 C CG . HIS A 1 381 ? 1.106 22.458 28.835 1.00 16.56 ? 377 HIS A CG 1 ATOM 2940 N ND1 . HIS A 1 381 ? 0.452 21.264 28.582 1.00 22.20 ? 377 HIS A ND1 1 ATOM 2941 C CD2 . HIS A 1 381 ? 2.045 22.598 27.878 1.00 14.31 ? 377 HIS A CD2 1 ATOM 2942 C CE1 . HIS A 1 381 ? 0.993 20.696 27.508 1.00 19.47 ? 377 HIS A CE1 1 ATOM 2943 N NE2 . HIS A 1 381 ? 1.955 21.493 27.059 1.00 23.53 ? 377 HIS A NE2 1 ATOM 2944 N N . ARG A 1 382 ? -1.102 25.100 31.772 1.00 14.22 ? 378 ARG A N 1 ATOM 2945 C CA . ARG A 1 382 ? -1.358 26.004 32.893 1.00 13.33 ? 378 ARG A CA 1 ATOM 2946 C C . ARG A 1 382 ? -2.315 25.385 33.903 1.00 14.38 ? 378 ARG A C 1 ATOM 2947 O O . ARG A 1 382 ? -2.127 25.526 35.115 1.00 13.85 ? 378 ARG A O 1 ATOM 2948 C CB . ARG A 1 382 ? -1.867 27.353 32.387 1.00 12.91 ? 378 ARG A CB 1 ATOM 2949 C CG . ARG A 1 382 ? -0.798 28.084 31.602 1.00 15.12 ? 378 ARG A CG 1 ATOM 2950 C CD . ARG A 1 382 ? -1.293 29.492 31.298 1.00 14.74 ? 378 ARG A CD 1 ATOM 2951 N NE . ARG A 1 382 ? -0.359 30.120 30.352 1.00 15.92 ? 378 ARG A NE 1 ATOM 2952 C CZ . ARG A 1 382 ? 0.730 30.770 30.694 1.00 16.49 ? 378 ARG A CZ 1 ATOM 2953 N NH1 . ARG A 1 382 ? 1.058 30.962 31.971 1.00 15.52 ? 378 ARG A NH1 1 ATOM 2954 N NH2 . ARG A 1 382 ? 1.496 31.283 29.712 1.00 16.77 ? 378 ARG A NH2 1 ATOM 2955 N N . ASP A 1 383 ? -3.305 24.645 33.382 1.00 14.61 ? 379 ASP A N 1 ATOM 2956 C CA . ASP A 1 383 ? -4.224 23.936 34.306 1.00 14.36 ? 379 ASP A CA 1 ATOM 2957 C C . ASP A 1 383 ? -3.497 22.891 35.138 1.00 14.05 ? 379 ASP A C 1 ATOM 2958 O O . ASP A 1 383 ? -3.757 22.726 36.336 1.00 14.02 ? 379 ASP A O 1 ATOM 2959 C CB . ASP A 1 383 ? -5.370 23.261 33.524 1.00 14.74 ? 379 ASP A CB 1 ATOM 2960 C CG . ASP A 1 383 ? -6.335 24.253 32.860 1.00 18.64 ? 379 ASP A CG 1 ATOM 2961 O OD1 . ASP A 1 383 ? -6.368 25.464 33.190 1.00 20.30 ? 379 ASP A OD1 1 ATOM 2962 O OD2 . ASP A 1 383 ? -7.028 23.771 31.924 1.00 22.93 ? 379 ASP A OD2 1 ATOM 2963 N N . LEU A 1 384 ? -2.504 22.192 34.539 1.00 13.11 ? 380 LEU A N 1 ATOM 2964 C CA . LEU A 1 384 ? -1.680 21.230 35.247 1.00 14.24 ? 380 LEU A CA 1 ATOM 2965 C C . LEU A 1 384 ? -0.812 21.954 36.284 1.00 14.04 ? 380 LEU A C 1 ATOM 2966 O O . LEU A 1 384 ? -0.698 21.490 37.407 1.00 13.74 ? 380 LEU A O 1 ATOM 2967 C CB . LEU A 1 384 ? -0.811 20.474 34.210 1.00 13.96 ? 380 LEU A CB 1 ATOM 2968 C CG . LEU A 1 384 ? 0.211 19.552 34.843 1.00 15.86 ? 380 LEU A CG 1 ATOM 2969 C CD1 . LEU A 1 384 ? -0.407 18.378 35.576 1.00 17.92 ? 380 LEU A CD1 1 ATOM 2970 C CD2 . LEU A 1 384 ? 1.122 18.985 33.739 1.00 16.44 ? 380 LEU A CD2 1 ATOM 2971 N N . ALA A 1 385 ? -0.239 23.124 35.917 1.00 13.49 ? 381 ALA A N 1 ATOM 2972 C CA . ALA A 1 385 ? 0.646 23.862 36.833 1.00 13.96 ? 381 ALA A CA 1 ATOM 2973 C C . ALA A 1 385 ? -0.196 24.358 38.018 1.00 12.83 ? 381 ALA A C 1 ATOM 2974 O O . ALA A 1 385 ? 0.275 24.306 39.134 1.00 13.38 ? 381 ALA A O 1 ATOM 2975 C CB . ALA A 1 385 ? 1.302 25.041 36.103 1.00 12.63 ? 381 ALA A CB 1 ATOM 2976 N N . ARG A 1 386 ? -1.458 24.744 37.752 1.00 13.07 ? 382 ARG A N 1 ATOM 2977 C CA . ARG A 1 386 ? -2.380 25.193 38.817 1.00 13.08 ? 382 ARG A CA 1 ATOM 2978 C C . ARG A 1 386 ? -2.727 24.049 39.779 1.00 14.37 ? 382 ARG A C 1 ATOM 2979 O O . ARG A 1 386 ? -2.759 24.260 40.987 1.00 14.45 ? 382 ARG A O 1 ATOM 2980 C CB . ARG A 1 386 ? -3.652 25.701 38.130 1.00 12.83 ? 382 ARG A CB 1 ATOM 2981 C CG . ARG A 1 386 ? -4.702 26.195 39.092 1.00 14.76 ? 382 ARG A CG 1 ATOM 2982 C CD . ARG A 1 386 ? -5.797 26.815 38.236 1.00 15.33 ? 382 ARG A CD 1 ATOM 2983 N NE . ARG A 1 386 ? -6.965 27.160 39.072 1.00 15.56 ? 382 ARG A NE 1 ATOM 2984 C CZ . ARG A 1 386 ? -8.036 27.781 38.596 1.00 17.04 ? 382 ARG A CZ 1 ATOM 2985 N NH1 . ARG A 1 386 ? -8.105 28.133 37.306 1.00 19.60 ? 382 ARG A NH1 1 ATOM 2986 N NH2 . ARG A 1 386 ? -9.052 28.050 39.442 1.00 17.87 ? 382 ARG A NH2 1 ATOM 2987 N N . GLU A 1 387 ? -2.999 22.853 39.234 1.00 12.64 ? 383 GLU A N 1 ATOM 2988 C CA . GLU A 1 387 ? -3.178 21.653 40.056 1.00 13.17 ? 383 GLU A CA 1 ATOM 2989 C C . GLU A 1 387 ? -1.940 21.384 40.923 1.00 13.81 ? 383 GLU A C 1 ATOM 2990 O O . GLU A 1 387 ? -1.998 21.131 42.125 1.00 14.79 ? 383 GLU A O 1 ATOM 2991 C CB . GLU A 1 387 ? -3.474 20.450 39.124 1.00 14.24 ? 383 GLU A CB 1 ATOM 2992 C CG . GLU A 1 387 ? -3.453 19.130 39.899 1.00 16.50 ? 383 GLU A CG 1 ATOM 2993 C CD . GLU A 1 387 ? -3.546 17.903 38.942 1.00 20.28 ? 383 GLU A CD 1 ATOM 2994 O OE1 . GLU A 1 387 ? -3.740 18.086 37.718 1.00 23.68 ? 383 GLU A OE1 1 ATOM 2995 O OE2 . GLU A 1 387 ? -3.406 16.769 39.431 1.00 21.20 ? 383 GLU A OE2 1 ATOM 2996 N N . ALA A 1 388 ? -0.765 21.439 40.304 1.00 13.13 ? 384 ALA A N 1 ATOM 2997 C CA . ALA A 1 388 ? 0.458 21.187 41.035 1.00 12.42 ? 384 ALA A CA 1 ATOM 2998 C C . ALA A 1 388 ? 0.730 22.200 42.175 1.00 12.65 ? 384 ALA A C 1 ATOM 2999 O O . ALA A 1 388 ? 1.125 21.846 43.287 1.00 13.29 ? 384 ALA A O 1 ATOM 3000 C CB . ALA A 1 388 ? 1.634 21.175 40.006 1.00 13.59 ? 384 ALA A CB 1 ATOM 3001 N N . ALA A 1 389 ? 0.532 23.491 41.863 1.00 12.06 ? 385 ALA A N 1 ATOM 3002 C CA . ALA A 1 389 ? 0.748 24.539 42.853 1.00 12.51 ? 385 ALA A CA 1 ATOM 3003 C C . ALA A 1 389 ? -0.186 24.293 44.047 1.00 12.45 ? 385 ALA A C 1 ATOM 3004 O O . ALA A 1 389 ? 0.266 24.303 45.188 1.00 13.60 ? 385 ALA A O 1 ATOM 3005 C CB . ALA A 1 389 ? 0.483 25.896 42.216 1.00 13.16 ? 385 ALA A CB 1 ATOM 3006 N N . ARG A 1 390 ? -1.456 23.983 43.748 1.00 12.54 ? 386 ARG A N 1 ATOM 3007 C CA . ARG A 1 390 ? -2.441 23.715 44.840 1.00 13.35 ? 386 ARG A CA 1 ATOM 3008 C C . ARG A 1 390 ? -2.007 22.505 45.661 1.00 13.73 ? 386 ARG A C 1 ATOM 3009 O O . ARG A 1 390 ? -2.029 22.549 46.919 1.00 14.71 ? 386 ARG A O 1 ATOM 3010 C CB . ARG A 1 390 ? -3.793 23.496 44.205 1.00 14.63 ? 386 ARG A CB 1 ATOM 3011 C CG . ARG A 1 390 ? -4.935 23.123 45.237 1.00 18.77 ? 386 ARG A CG 1 ATOM 3012 C CD . ARG A 1 390 ? -5.346 21.638 45.079 1.00 22.74 ? 386 ARG A CD 1 ATOM 3013 N NE . ARG A 1 390 ? -5.807 21.293 43.739 1.00 25.13 ? 386 ARG A NE 1 ATOM 3014 C CZ . ARG A 1 390 ? -6.116 20.064 43.383 1.00 26.25 ? 386 ARG A CZ 1 ATOM 3015 N NH1 . ARG A 1 390 ? -6.044 19.095 44.290 1.00 25.67 ? 386 ARG A NH1 1 ATOM 3016 N NH2 . ARG A 1 390 ? -6.489 19.828 42.160 1.00 28.66 ? 386 ARG A NH2 1 ATOM 3017 N N . LYS A 1 391 ? -1.575 21.432 44.983 1.00 12.81 ? 387 LYS A N 1 ATOM 3018 C CA . LYS A 1 391 ? -1.181 20.218 45.723 1.00 15.13 ? 387 LYS A CA 1 ATOM 3019 C C . LYS A 1 391 ? 0.104 20.402 46.526 1.00 13.75 ? 387 LYS A C 1 ATOM 3020 O O . LYS A 1 391 ? 0.373 19.673 47.490 1.00 15.26 ? 387 LYS A O 1 ATOM 3021 C CB . LYS A 1 391 ? -1.046 19.017 44.751 1.00 14.19 ? 387 LYS A CB 1 ATOM 3022 C CG . LYS A 1 391 ? -2.382 18.521 44.264 1.00 15.14 ? 387 LYS A CG 1 ATOM 3023 C CD . LYS A 1 391 ? -2.178 17.464 43.195 1.00 17.85 ? 387 LYS A CD 1 ATOM 3024 C CE . LYS A 1 391 ? -3.513 16.772 42.961 1.00 21.42 ? 387 LYS A CE 1 ATOM 3025 N NZ . LYS A 1 391 ? -3.294 15.667 41.978 1.00 22.04 ? 387 LYS A NZ 1 ATOM 3026 N N . SER A 1 392 ? 0.942 21.385 46.143 1.00 13.19 ? 388 SER A N 1 ATOM 3027 C CA . SER A 1 392 ? 2.227 21.612 46.820 1.00 12.93 ? 388 SER A CA 1 ATOM 3028 C C . SER A 1 392 ? 2.080 22.371 48.137 1.00 13.02 ? 388 SER A C 1 ATOM 3029 O O . SER A 1 392 ? 3.013 22.370 48.966 1.00 13.68 ? 388 SER A O 1 ATOM 3030 C CB . SER A 1 392 ? 3.187 22.388 45.895 1.00 13.87 ? 388 SER A CB 1 ATOM 3031 O OG . SER A 1 392 ? 2.831 23.792 45.813 1.00 13.44 ? 388 SER A OG 1 ATOM 3032 N N . LEU A 1 393 ? 0.924 23.035 48.330 1.00 13.69 ? 389 LEU A N 1 ATOM 3033 C CA . LEU A 1 393 ? 0.795 23.950 49.504 1.00 14.34 ? 389 LEU A CA 1 ATOM 3034 C C . LEU A 1 393 ? 0.745 23.098 50.781 1.00 14.71 ? 389 LEU A C 1 ATOM 3035 O O . LEU A 1 393 ? 0.018 22.096 50.833 1.00 15.24 ? 389 LEU A O 1 ATOM 3036 C CB . LEU A 1 393 ? -0.522 24.708 49.439 1.00 13.28 ? 389 LEU A CB 1 ATOM 3037 C CG . LEU A 1 393 ? -0.764 25.496 48.140 1.00 14.17 ? 389 LEU A CG 1 ATOM 3038 C CD1 . LEU A 1 393 ? -2.200 26.164 48.160 1.00 15.27 ? 389 LEU A CD1 1 ATOM 3039 C CD2 . LEU A 1 393 ? 0.331 26.570 47.817 1.00 15.64 ? 389 LEU A CD2 1 ATOM 3040 N N . VAL A 1 394 ? 1.474 23.544 51.789 1.00 14.66 ? 390 VAL A N 1 ATOM 3041 C CA . VAL A 1 394 ? 1.413 22.857 53.111 1.00 15.39 ? 390 VAL A CA 1 ATOM 3042 C C . VAL A 1 394 ? 0.810 23.839 54.116 1.00 15.16 ? 390 VAL A C 1 ATOM 3043 O O . VAL A 1 394 ? 1.378 24.892 54.446 1.00 15.65 ? 390 VAL A O 1 ATOM 3044 C CB . VAL A 1 394 ? 2.784 22.357 53.549 1.00 15.46 ? 390 VAL A CB 1 ATOM 3045 C CG1 . VAL A 1 394 ? 2.599 21.585 54.924 1.00 17.73 ? 390 VAL A CG1 1 ATOM 3046 C CG2 . VAL A 1 394 ? 3.364 21.387 52.485 1.00 16.18 ? 390 VAL A CG2 1 ATOM 3047 N N . LEU A 1 395 ? -0.344 23.433 54.647 1.00 15.78 ? 391 LEU A N 1 ATOM 3048 C CA . LEU A 1 395 ? -1.028 24.223 55.675 1.00 16.05 ? 391 LEU A CA 1 ATOM 3049 C C . LEU A 1 395 ? -0.360 23.939 57.007 1.00 16.21 ? 391 LEU A C 1 ATOM 3050 O O . LEU A 1 395 ? -0.379 22.785 57.484 1.00 16.88 ? 391 LEU A O 1 ATOM 3051 C CB . LEU A 1 395 ? -2.497 23.841 55.680 1.00 16.00 ? 391 LEU A CB 1 ATOM 3052 C CG . LEU A 1 395 ? -3.415 24.575 56.695 1.00 14.92 ? 391 LEU A CG 1 ATOM 3053 C CD1 . LEU A 1 395 ? -3.420 26.102 56.387 1.00 15.27 ? 391 LEU A CD1 1 ATOM 3054 C CD2 . LEU A 1 395 ? -4.791 23.997 56.562 1.00 16.24 ? 391 LEU A CD2 1 ATOM 3055 N N . LEU A 1 396 ? 0.235 24.979 57.602 1.00 15.83 ? 392 LEU A N 1 ATOM 3056 C CA . LEU A 1 396 ? 1.012 24.802 58.853 1.00 16.00 ? 392 LEU A CA 1 ATOM 3057 C C . LEU A 1 396 ? 0.185 25.175 60.076 1.00 17.00 ? 392 LEU A C 1 ATOM 3058 O O . LEU A 1 396 ? 0.461 24.653 61.189 1.00 20.06 ? 392 LEU A O 1 ATOM 3059 C CB . LEU A 1 396 ? 2.300 25.605 58.836 1.00 17.27 ? 392 LEU A CB 1 ATOM 3060 C CG . LEU A 1 396 ? 3.344 25.203 57.754 1.00 17.48 ? 392 LEU A CG 1 ATOM 3061 C CD1 . LEU A 1 396 ? 4.587 26.078 57.870 1.00 19.86 ? 392 LEU A CD1 1 ATOM 3062 C CD2 . LEU A 1 396 ? 3.691 23.713 57.886 1.00 20.67 ? 392 LEU A CD2 1 ATOM 3063 N N . LYS A 1 397 ? -0.787 26.079 59.895 1.00 17.86 ? 393 LYS A N 1 ATOM 3064 C CA . LYS A 1 397 ? -1.630 26.581 61.026 1.00 17.75 ? 393 LYS A CA 1 ATOM 3065 C C . LYS A 1 397 ? -2.967 26.991 60.451 1.00 17.47 ? 393 LYS A C 1 ATOM 3066 O O . LYS A 1 397 ? -3.021 27.617 59.384 1.00 16.37 ? 393 LYS A O 1 ATOM 3067 C CB . LYS A 1 397 ? -0.910 27.787 61.645 1.00 18.31 ? 393 LYS A CB 1 ATOM 3068 C CG . LYS A 1 397 ? -1.571 28.313 62.917 1.00 21.66 ? 393 LYS A CG 1 ATOM 3069 C CD . LYS A 1 397 ? -0.837 29.540 63.383 1.00 19.90 ? 393 LYS A CD 1 ATOM 3070 C CE . LYS A 1 397 ? -1.574 30.139 64.592 1.00 21.35 ? 393 LYS A CE 1 ATOM 3071 N NZ . LYS A 1 397 ? -0.796 31.113 65.346 1.00 24.20 ? 393 LYS A NZ 1 ATOM 3072 N N . ASN A 1 398 ? -4.059 26.716 61.164 1.00 18.16 ? 394 ASN A N 1 ATOM 3073 C CA . ASN A 1 398 ? -5.386 27.098 60.697 1.00 18.43 ? 394 ASN A CA 1 ATOM 3074 C C . ASN A 1 398 ? -6.232 27.426 61.921 1.00 22.16 ? 394 ASN A C 1 ATOM 3075 O O . ASN A 1 398 ? -7.065 26.633 62.330 1.00 25.11 ? 394 ASN A O 1 ATOM 3076 C CB . ASN A 1 398 ? -6.028 26.013 59.837 1.00 18.17 ? 394 ASN A CB 1 ATOM 3077 C CG . ASN A 1 398 ? -7.267 26.498 59.088 1.00 18.19 ? 394 ASN A CG 1 ATOM 3078 O OD1 . ASN A 1 398 ? -8.074 25.690 58.551 1.00 21.57 ? 394 ASN A OD1 1 ATOM 3079 N ND2 . ASN A 1 398 ? -7.398 27.801 58.990 1.00 17.08 ? 394 ASN A ND2 1 ATOM 3080 N N . GLY A 1 399 ? -5.866 28.531 62.543 1.00 24.07 ? 395 GLY A N 1 ATOM 3081 C CA . GLY A 1 399 ? -6.492 29.098 63.782 1.00 25.30 ? 395 GLY A CA 1 ATOM 3082 C C . GLY A 1 399 ? -5.432 29.331 64.835 1.00 26.84 ? 395 GLY A C 1 ATOM 3083 O O . GLY A 1 399 ? -4.605 28.466 65.069 1.00 26.71 ? 395 GLY A O 1 ATOM 3084 N N . LYS A 1 400 ? -5.484 30.462 65.568 1.00 29.72 ? 396 LYS A N 1 ATOM 3085 C CA . LYS A 1 400 ? -4.439 30.724 66.633 1.00 31.40 ? 396 LYS A CA 1 ATOM 3086 C C . LYS A 1 400 ? -4.529 29.850 67.856 1.00 33.67 ? 396 LYS A C 1 ATOM 3087 O O . LYS A 1 400 ? -3.562 29.669 68.627 1.00 35.65 ? 396 LYS A O 1 ATOM 3088 C CB . LYS A 1 400 ? -4.575 32.137 67.157 1.00 33.08 ? 396 LYS A CB 1 ATOM 3089 C CG . LYS A 1 400 ? -4.538 33.161 66.115 1.00 32.92 ? 396 LYS A CG 1 ATOM 3090 C CD . LYS A 1 400 ? -3.950 34.400 66.712 1.00 30.10 ? 396 LYS A CD 1 ATOM 3091 C CE . LYS A 1 400 ? -3.839 35.439 65.601 1.00 29.43 ? 396 LYS A CE 1 ATOM 3092 N NZ . LYS A 1 400 ? -3.611 36.821 66.087 1.00 31.64 ? 396 LYS A NZ 1 ATOM 3093 N N . THR A 1 401 ? -5.729 29.391 68.137 1.00 31.50 ? 397 THR A N 1 ATOM 3094 C CA . THR A 1 401 ? -5.870 28.487 69.208 1.00 31.36 ? 397 THR A CA 1 ATOM 3095 C C . THR A 1 401 ? -6.683 27.372 68.647 1.00 31.26 ? 397 THR A C 1 ATOM 3096 O O . THR A 1 401 ? -7.390 27.503 67.607 1.00 29.03 ? 397 THR A O 1 ATOM 3097 C CB . THR A 1 401 ? -6.555 29.115 70.460 1.00 31.67 ? 397 THR A CB 1 ATOM 3098 O OG1 . THR A 1 401 ? -7.967 29.157 70.264 1.00 32.23 ? 397 THR A OG1 1 ATOM 3099 C CG2 . THR A 1 401 ? -6.049 30.517 70.716 1.00 33.02 ? 397 THR A CG2 1 ATOM 3100 N N . SER A 1 402 ? -6.588 26.284 69.369 1.00 31.49 ? 398 SER A N 1 ATOM 3101 C CA . SER A 1 402 ? -7.228 25.080 68.984 1.00 31.17 ? 398 SER A CA 1 ATOM 3102 C C . SER A 1 402 ? -8.736 25.231 69.133 1.00 29.20 ? 398 SER A C 1 ATOM 3103 O O . SER A 1 402 ? -9.480 24.380 68.669 1.00 29.43 ? 398 SER A O 1 ATOM 3104 C CB . SER A 1 402 ? -6.707 23.963 69.869 1.00 32.43 ? 398 SER A CB 1 ATOM 3105 O OG . SER A 1 402 ? -7.163 24.181 71.183 1.00 36.51 ? 398 SER A OG 1 ATOM 3106 N N . THR A 1 403 ? -9.201 26.295 69.779 1.00 26.09 ? 399 THR A N 1 ATOM 3107 C CA . THR A 1 403 ? -10.648 26.507 69.879 1.00 25.22 ? 399 THR A CA 1 ATOM 3108 C C . THR A 1 403 ? -11.228 27.620 68.988 1.00 22.90 ? 399 THR A C 1 ATOM 3109 O O . THR A 1 403 ? -12.470 27.834 68.967 1.00 22.36 ? 399 THR A O 1 ATOM 3110 C CB . THR A 1 403 ? -11.068 26.815 71.314 1.00 26.07 ? 399 THR A CB 1 ATOM 3111 O OG1 . THR A 1 403 ? -10.362 27.976 71.722 1.00 26.10 ? 399 THR A OG1 1 ATOM 3112 C CG2 . THR A 1 403 ? -10.774 25.618 72.261 1.00 28.12 ? 399 THR A CG2 1 ATOM 3113 N N . ASP A 1 404 ? -10.376 28.320 68.246 1.00 19.38 ? 400 ASP A N 1 ATOM 3114 C CA . ASP A 1 404 ? -10.858 29.331 67.329 1.00 17.88 ? 400 ASP A CA 1 ATOM 3115 C C . ASP A 1 404 ? -11.553 28.675 66.133 1.00 17.13 ? 400 ASP A C 1 ATOM 3116 O O . ASP A 1 404 ? -11.286 27.507 65.791 1.00 18.53 ? 400 ASP A O 1 ATOM 3117 C CB . ASP A 1 404 ? -9.630 30.089 66.769 1.00 17.42 ? 400 ASP A CB 1 ATOM 3118 C CG . ASP A 1 404 ? -9.143 31.177 67.708 1.00 19.61 ? 400 ASP A CG 1 ATOM 3119 O OD1 . ASP A 1 404 ? -9.522 31.161 68.917 1.00 21.03 ? 400 ASP A OD1 1 ATOM 3120 O OD2 . ASP A 1 404 ? -8.432 32.084 67.225 1.00 22.55 ? 400 ASP A OD2 1 ATOM 3121 N N . ALA A 1 405 ? -12.410 29.428 65.464 1.00 15.77 ? 401 ALA A N 1 ATOM 3122 C CA . ALA A 1 405 ? -12.996 28.981 64.211 1.00 16.27 ? 401 ALA A CA 1 ATOM 3123 C C . ALA A 1 405 ? -11.825 28.790 63.223 1.00 17.69 ? 401 ALA A C 1 ATOM 3124 O O . ALA A 1 405 ? -10.914 29.612 63.187 1.00 18.55 ? 401 ALA A O 1 ATOM 3125 C CB . ALA A 1 405 ? -13.830 30.090 63.714 1.00 17.48 ? 401 ALA A CB 1 ATOM 3126 N N . PRO A 1 406 ? -11.885 27.740 62.401 1.00 19.06 ? 402 PRO A N 1 ATOM 3127 C CA . PRO A 1 406 ? -10.833 27.605 61.355 1.00 20.23 ? 402 PRO A CA 1 ATOM 3128 C C . PRO A 1 406 ? -10.955 28.766 60.375 1.00 18.93 ? 402 PRO A C 1 ATOM 3129 O O . PRO A 1 406 ? -12.025 29.057 59.869 1.00 20.61 ? 402 PRO A O 1 ATOM 3130 C CB . PRO A 1 406 ? -11.224 26.310 60.635 1.00 21.60 ? 402 PRO A CB 1 ATOM 3131 C CG . PRO A 1 406 ? -12.706 26.069 60.969 1.00 23.91 ? 402 PRO A CG 1 ATOM 3132 C CD . PRO A 1 406 ? -12.835 26.603 62.394 1.00 21.50 ? 402 PRO A CD 1 ATOM 3133 N N . LEU A 1 407 ? -9.835 29.414 60.075 1.00 17.41 ? 403 LEU A N 1 ATOM 3134 C CA . LEU A 1 407 ? -9.870 30.554 59.178 1.00 17.66 ? 403 LEU A CA 1 ATOM 3135 C C . LEU A 1 407 ? -10.091 30.061 57.730 1.00 15.79 ? 403 LEU A C 1 ATOM 3136 O O . LEU A 1 407 ? -10.877 30.614 56.981 1.00 16.00 ? 403 LEU A O 1 ATOM 3137 C CB . LEU A 1 407 ? -8.539 31.369 59.267 1.00 18.01 ? 403 LEU A CB 1 ATOM 3138 C CG . LEU A 1 407 ? -8.639 32.523 58.242 1.00 23.34 ? 403 LEU A CG 1 ATOM 3139 C CD1 . LEU A 1 407 ? -9.623 33.630 58.756 1.00 24.10 ? 403 LEU A CD1 1 ATOM 3140 C CD2 . LEU A 1 407 ? -7.383 33.117 57.896 1.00 27.58 ? 403 LEU A CD2 1 ATOM 3141 N N . LEU A 1 408 ? -9.364 28.996 57.346 1.00 15.67 ? 404 LEU A N 1 ATOM 3142 C CA . LEU A 1 408 ? -9.476 28.462 55.989 1.00 16.69 ? 404 LEU A CA 1 ATOM 3143 C C . LEU A 1 408 ? -10.401 27.253 55.958 1.00 16.95 ? 404 LEU A C 1 ATOM 3144 O O . LEU A 1 408 ? -10.342 26.454 56.906 1.00 18.43 ? 404 LEU A O 1 ATOM 3145 C CB . LEU A 1 408 ? -8.091 28.032 55.458 1.00 15.73 ? 404 LEU A CB 1 ATOM 3146 C CG . LEU A 1 408 ? -7.107 29.207 55.423 1.00 16.18 ? 404 LEU A CG 1 ATOM 3147 C CD1 . LEU A 1 408 ? -5.695 28.689 54.869 1.00 17.16 ? 404 LEU A CD1 1 ATOM 3148 C CD2 . LEU A 1 408 ? -7.603 30.365 54.555 1.00 14.85 ? 404 LEU A CD2 1 ATOM 3149 N N . PRO A 1 409 ? -11.241 27.139 54.914 1.00 16.79 ? 405 PRO A N 1 ATOM 3150 C CA . PRO A 1 409 ? -11.347 28.063 53.770 1.00 18.65 ? 405 PRO A CA 1 ATOM 3151 C C . PRO A 1 409 ? -12.045 29.390 54.051 1.00 17.37 ? 405 PRO A C 1 ATOM 3152 O O . PRO A 1 409 ? -13.038 29.464 54.833 1.00 18.13 ? 405 PRO A O 1 ATOM 3153 C CB . PRO A 1 409 ? -12.167 27.282 52.722 1.00 20.24 ? 405 PRO A CB 1 ATOM 3154 C CG . PRO A 1 409 ? -12.877 26.205 53.513 1.00 23.00 ? 405 PRO A CG 1 ATOM 3155 C CD . PRO A 1 409 ? -12.065 25.912 54.724 1.00 19.16 ? 405 PRO A CD 1 ATOM 3156 N N . LEU A 1 410 ? -11.601 30.426 53.355 1.00 16.02 ? 406 LEU A N 1 ATOM 3157 C CA . LEU A 1 410 ? -12.193 31.746 53.432 1.00 16.94 ? 406 LEU A CA 1 ATOM 3158 C C . LEU A 1 410 ? -13.442 31.790 52.555 1.00 17.85 ? 406 LEU A C 1 ATOM 3159 O O . LEU A 1 410 ? -13.512 31.116 51.500 1.00 16.90 ? 406 LEU A O 1 ATOM 3160 C CB . LEU A 1 410 ? -11.189 32.750 52.858 1.00 17.63 ? 406 LEU A CB 1 ATOM 3161 C CG . LEU A 1 410 ? -9.932 32.845 53.735 1.00 21.01 ? 406 LEU A CG 1 ATOM 3162 C CD1 . LEU A 1 410 ? -8.886 33.606 52.933 1.00 24.45 ? 406 LEU A CD1 1 ATOM 3163 C CD2 . LEU A 1 410 ? -10.204 33.546 55.017 1.00 24.30 ? 406 LEU A CD2 1 ATOM 3164 N N . PRO A 1 411 ? -14.389 32.674 52.892 1.00 17.57 ? 407 PRO A N 1 ATOM 3165 C CA . PRO A 1 411 ? -15.520 32.833 52.016 1.00 17.23 ? 407 PRO A CA 1 ATOM 3166 C C . PRO A 1 411 ? -15.204 33.706 50.807 1.00 17.17 ? 407 PRO A C 1 ATOM 3167 O O . PRO A 1 411 ? -14.574 34.759 50.895 1.00 18.81 ? 407 PRO A O 1 ATOM 3168 C CB . PRO A 1 411 ? -16.564 33.557 52.911 1.00 18.26 ? 407 PRO A CB 1 ATOM 3169 C CG . PRO A 1 411 ? -15.692 34.414 53.846 1.00 19.21 ? 407 PRO A CG 1 ATOM 3170 C CD . PRO A 1 411 ? -14.452 33.547 54.095 1.00 16.92 ? 407 PRO A CD 1 ATOM 3171 N N . LYS A 1 412 ? -15.764 33.315 49.661 1.00 15.44 ? 408 LYS A N 1 ATOM 3172 C CA . LYS A 1 412 ? -15.641 34.131 48.469 1.00 15.77 ? 408 LYS A CA 1 ATOM 3173 C C . LYS A 1 412 ? -16.494 35.382 48.445 1.00 15.86 ? 408 LYS A C 1 ATOM 3174 O O . LYS A 1 412 ? -16.210 36.294 47.692 1.00 16.18 ? 408 LYS A O 1 ATOM 3175 C CB . LYS A 1 412 ? -15.957 33.276 47.204 1.00 15.69 ? 408 LYS A CB 1 ATOM 3176 C CG . LYS A 1 412 ? -14.955 32.161 46.969 1.00 16.48 ? 408 LYS A CG 1 ATOM 3177 C CD . LYS A 1 412 ? -15.437 31.383 45.729 1.00 17.76 ? 408 LYS A CD 1 ATOM 3178 C CE . LYS A 1 412 ? -14.580 30.153 45.593 1.00 20.66 ? 408 LYS A CE 1 ATOM 3179 N NZ . LYS A 1 412 ? -14.974 29.382 44.355 1.00 20.90 ? 408 LYS A NZ 1 ATOM 3180 N N . LYS A 1 413 ? -17.567 35.412 49.265 1.00 17.58 ? 409 LYS A N 1 ATOM 3181 C CA . LYS A 1 413 ? -18.395 36.599 49.341 1.00 18.39 ? 409 LYS A CA 1 ATOM 3182 C C . LYS A 1 413 ? -18.173 37.267 50.692 1.00 18.42 ? 409 LYS A C 1 ATOM 3183 O O . LYS A 1 413 ? -18.417 36.678 51.751 1.00 20.06 ? 409 LYS A O 1 ATOM 3184 C CB . LYS A 1 413 ? -19.878 36.241 49.174 1.00 19.00 ? 409 LYS A CB 1 ATOM 3185 C CG . LYS A 1 413 ? -20.743 37.490 49.039 1.00 23.86 ? 409 LYS A CG 1 ATOM 3186 C CD . LYS A 1 413 ? -22.190 37.070 48.854 1.00 31.84 ? 409 LYS A CD 1 ATOM 3187 C CE . LYS A 1 413 ? -23.083 38.279 48.705 1.00 37.60 ? 409 LYS A CE 1 ATOM 3188 N NZ . LYS A 1 413 ? -24.516 37.832 48.688 1.00 42.16 ? 409 LYS A NZ 1 ATOM 3189 N N . ALA A 1 414 ? -17.726 38.513 50.614 1.00 18.08 ? 410 ALA A N 1 ATOM 3190 C CA . ALA A 1 414 ? -17.508 39.381 51.796 1.00 18.46 ? 410 ALA A CA 1 ATOM 3191 C C . ALA A 1 414 ? -17.557 40.829 51.322 1.00 19.46 ? 410 ALA A C 1 ATOM 3192 O O . ALA A 1 414 ? -17.221 41.134 50.194 1.00 20.08 ? 410 ALA A O 1 ATOM 3193 C CB . ALA A 1 414 ? -16.169 39.042 52.428 1.00 18.55 ? 410 ALA A CB 1 ATOM 3194 N N . PRO A 1 415 ? -17.951 41.785 52.184 1.00 18.68 ? 411 PRO A N 1 ATOM 3195 C CA . PRO A 1 415 ? -18.086 43.116 51.620 1.00 19.06 ? 411 PRO A CA 1 ATOM 3196 C C . PRO A 1 415 ? -16.750 43.693 51.094 1.00 17.51 ? 411 PRO A C 1 ATOM 3197 O O . PRO A 1 415 ? -16.724 44.336 50.025 1.00 19.04 ? 411 PRO A O 1 ATOM 3198 C CB . PRO A 1 415 ? -18.650 43.947 52.801 1.00 20.02 ? 411 PRO A CB 1 ATOM 3199 C CG . PRO A 1 415 ? -19.405 42.916 53.609 1.00 19.52 ? 411 PRO A CG 1 ATOM 3200 C CD . PRO A 1 415 ? -18.550 41.648 53.527 1.00 20.29 ? 411 PRO A CD 1 ATOM 3201 N N . LYS A 1 416 ? -15.674 43.500 51.849 1.00 17.89 ? 412 LYS A N 1 ATOM 3202 C CA . LYS A 1 416 ? -14.410 44.116 51.506 1.00 17.51 ? 412 LYS A CA 1 ATOM 3203 C C . LYS A 1 416 ? -13.308 43.256 52.105 1.00 16.44 ? 412 LYS A C 1 ATOM 3204 O O . LYS A 1 416 ? -13.401 42.839 53.252 1.00 15.78 ? 412 LYS A O 1 ATOM 3205 C CB . LYS A 1 416 ? -14.373 45.564 52.069 1.00 18.10 ? 412 LYS A CB 1 ATOM 3206 C CG . LYS A 1 416 ? -13.241 46.405 51.629 1.00 21.89 ? 412 LYS A CG 1 ATOM 3207 C CD . LYS A 1 416 ? -13.458 47.785 52.347 1.00 24.44 ? 412 LYS A CD 1 ATOM 3208 C CE . LYS A 1 416 ? -12.337 48.656 52.058 1.00 30.73 ? 412 LYS A CE 1 ATOM 3209 N NZ . LYS A 1 416 ? -12.673 49.958 52.729 1.00 29.13 ? 412 LYS A NZ 1 ATOM 3210 N N . ILE A 1 417 ? -12.271 42.918 51.299 1.00 16.11 ? 413 ILE A N 1 ATOM 3211 C CA . ILE A 1 417 ? -11.130 42.146 51.817 1.00 15.36 ? 413 ILE A CA 1 ATOM 3212 C C . ILE A 1 417 ? -9.807 42.800 51.432 1.00 14.77 ? 413 ILE A C 1 ATOM 3213 O O . ILE A 1 417 ? -9.789 43.658 50.543 1.00 16.09 ? 413 ILE A O 1 ATOM 3214 C CB . ILE A 1 417 ? -11.150 40.678 51.241 1.00 15.99 ? 413 ILE A CB 1 ATOM 3215 C CG1 . ILE A 1 417 ? -10.932 40.668 49.714 1.00 15.21 ? 413 ILE A CG1 1 ATOM 3216 C CG2 . ILE A 1 417 ? -12.493 40.042 51.583 1.00 17.25 ? 413 ILE A CG2 1 ATOM 3217 C CD1 . ILE A 1 417 ? -10.718 39.238 49.175 1.00 17.21 ? 413 ILE A CD1 1 ATOM 3218 N N . LEU A 1 418 ? -8.747 42.464 52.188 1.00 13.60 ? 414 LEU A N 1 ATOM 3219 C CA . LEU A 1 418 ? -7.434 43.074 51.927 1.00 14.97 ? 414 LEU A CA 1 ATOM 3220 C C . LEU A 1 418 ? -6.494 41.989 51.413 1.00 14.83 ? 414 LEU A C 1 ATOM 3221 O O . LEU A 1 418 ? -6.430 40.896 51.993 1.00 15.61 ? 414 LEU A O 1 ATOM 3222 C CB . LEU A 1 418 ? -6.888 43.674 53.266 1.00 14.42 ? 414 LEU A CB 1 ATOM 3223 C CG . LEU A 1 418 ? -5.445 44.195 53.177 1.00 16.15 ? 414 LEU A CG 1 ATOM 3224 C CD1 . LEU A 1 418 ? -5.366 45.359 52.193 1.00 15.77 ? 414 LEU A CD1 1 ATOM 3225 C CD2 . LEU A 1 418 ? -5.062 44.603 54.608 1.00 17.60 ? 414 LEU A CD2 1 ATOM 3226 N N . VAL A 1 419 ? -5.757 42.325 50.353 1.00 14.73 ? 415 VAL A N 1 ATOM 3227 C CA . VAL A 1 419 ? -4.622 41.502 49.892 1.00 15.33 ? 415 VAL A CA 1 ATOM 3228 C C . VAL A 1 419 ? -3.375 42.354 50.102 1.00 14.67 ? 415 VAL A C 1 ATOM 3229 O O . VAL A 1 419 ? -3.380 43.520 49.656 1.00 16.11 ? 415 VAL A O 1 ATOM 3230 C CB . VAL A 1 419 ? -4.794 41.125 48.402 1.00 15.32 ? 415 VAL A CB 1 ATOM 3231 C CG1 . VAL A 1 419 ? -3.544 40.325 47.876 1.00 14.74 ? 415 VAL A CG1 1 ATOM 3232 C CG2 . VAL A 1 419 ? -6.082 40.267 48.247 1.00 15.23 ? 415 VAL A CG2 1 ATOM 3233 N N . ALA A 1 420 ? -2.321 41.806 50.701 1.00 14.73 ? 416 ALA A N 1 ATOM 3234 C CA . ALA A 1 420 ? -1.186 42.635 51.100 1.00 14.27 ? 416 ALA A CA 1 ATOM 3235 C C . ALA A 1 420 ? 0.074 41.840 50.984 1.00 14.75 ? 416 ALA A C 1 ATOM 3236 O O . ALA A 1 420 ? 0.050 40.583 50.893 1.00 14.22 ? 416 ALA A O 1 ATOM 3237 C CB . ALA A 1 420 ? -1.384 43.153 52.579 1.00 14.58 ? 416 ALA A CB 1 ATOM 3238 N N . GLY A 1 421 ? 1.179 42.578 51.123 1.00 15.70 ? 417 GLY A N 1 ATOM 3239 C CA . GLY A 1 421 ? 2.486 41.949 51.193 1.00 14.90 ? 417 GLY A CA 1 ATOM 3240 C C . GLY A 1 421 ? 3.270 42.093 49.888 1.00 14.99 ? 417 GLY A C 1 ATOM 3241 O O . GLY A 1 421 ? 2.697 42.204 48.818 1.00 14.53 ? 417 GLY A O 1 ATOM 3242 N N . SER A 1 422 ? 4.598 42.046 50.027 1.00 15.10 ? 418 SER A N 1 ATOM 3243 C CA . SER A 1 422 ? 5.505 42.149 48.879 1.00 15.21 ? 418 SER A CA 1 ATOM 3244 C C . SER A 1 422 ? 5.374 41.027 47.858 1.00 15.20 ? 418 SER A C 1 ATOM 3245 O O . SER A 1 422 ? 5.805 41.181 46.712 1.00 16.26 ? 418 SER A O 1 ATOM 3246 C CB . SER A 1 422 ? 6.954 42.083 49.411 1.00 15.33 ? 418 SER A CB 1 ATOM 3247 O OG . SER A 1 422 ? 7.147 40.906 50.214 1.00 16.88 ? 418 SER A OG 1 ATOM 3248 N N . HIS A 1 423 ? 4.789 39.902 48.280 1.00 14.63 ? 419 HIS A N 1 ATOM 3249 C CA . HIS A 1 423 ? 4.681 38.750 47.374 1.00 14.39 ? 419 HIS A CA 1 ATOM 3250 C C . HIS A 1 423 ? 3.257 38.527 46.868 1.00 14.76 ? 419 HIS A C 1 ATOM 3251 O O . HIS A 1 423 ? 2.990 37.501 46.199 1.00 14.66 ? 419 HIS A O 1 ATOM 3252 C CB . HIS A 1 423 ? 5.206 37.484 48.067 1.00 14.59 ? 419 HIS A CB 1 ATOM 3253 C CG . HIS A 1 423 ? 6.692 37.476 48.267 1.00 14.89 ? 419 HIS A CG 1 ATOM 3254 N ND1 . HIS A 1 423 ? 7.365 38.458 48.956 1.00 15.83 ? 419 HIS A ND1 1 ATOM 3255 C CD2 . HIS A 1 423 ? 7.624 36.582 47.862 1.00 13.64 ? 419 HIS A CD2 1 ATOM 3256 C CE1 . HIS A 1 423 ? 8.668 38.181 48.954 1.00 14.92 ? 419 HIS A CE1 1 ATOM 3257 N NE2 . HIS A 1 423 ? 8.842 37.024 48.329 1.00 14.13 ? 419 HIS A NE2 1 ATOM 3258 N N . ALA A 1 424 ? 2.354 39.420 47.243 1.00 14.27 ? 420 ALA A N 1 ATOM 3259 C CA . ALA A 1 424 ? 0.946 39.253 46.781 1.00 13.71 ? 420 ALA A CA 1 ATOM 3260 C C . ALA A 1 424 ? 0.743 39.569 45.322 1.00 15.05 ? 420 ALA A C 1 ATOM 3261 O O . ALA A 1 424 ? -0.175 39.008 44.693 1.00 15.90 ? 420 ALA A O 1 ATOM 3262 C CB . ALA A 1 424 ? 0.013 40.104 47.607 1.00 16.56 ? 420 ALA A CB 1 ATOM 3263 N N . ASP A 1 425 ? 1.528 40.488 44.763 1.00 14.10 ? 421 ASP A N 1 ATOM 3264 C CA . ASP A 1 425 ? 1.344 40.856 43.379 1.00 14.85 ? 421 ASP A CA 1 ATOM 3265 C C . ASP A 1 425 ? 2.706 41.005 42.707 1.00 15.16 ? 421 ASP A C 1 ATOM 3266 O O . ASP A 1 425 ? 3.064 42.085 42.195 1.00 17.57 ? 421 ASP A O 1 ATOM 3267 C CB . ASP A 1 425 ? 0.582 42.211 43.311 1.00 14.71 ? 421 ASP A CB 1 ATOM 3268 C CG . ASP A 1 425 ? 0.139 42.532 41.906 1.00 17.65 ? 421 ASP A CG 1 ATOM 3269 O OD1 . ASP A 1 425 ? -0.284 41.639 41.149 1.00 18.44 ? 421 ASP A OD1 1 ATOM 3270 O OD2 . ASP A 1 425 ? 0.228 43.705 41.495 1.00 21.17 ? 421 ASP A OD2 1 ATOM 3271 N N . ASN A 1 426 ? 3.445 39.899 42.659 1.00 13.41 ? 422 ASN A N 1 ATOM 3272 C CA . ASN A 1 426 ? 4.796 39.928 42.082 1.00 13.91 ? 422 ASN A CA 1 ATOM 3273 C C . ASN A 1 426 ? 5.059 38.539 41.467 1.00 12.88 ? 422 ASN A C 1 ATOM 3274 O O . ASN A 1 426 ? 5.423 37.579 42.173 1.00 13.83 ? 422 ASN A O 1 ATOM 3275 C CB . ASN A 1 426 ? 5.822 40.268 43.172 1.00 14.84 ? 422 ASN A CB 1 ATOM 3276 C CG . ASN A 1 426 ? 7.210 40.498 42.594 1.00 14.92 ? 422 ASN A CG 1 ATOM 3277 O OD1 . ASN A 1 426 ? 7.626 39.816 41.657 1.00 14.04 ? 422 ASN A OD1 1 ATOM 3278 N ND2 . ASN A 1 426 ? 7.899 41.559 43.079 1.00 16.14 ? 422 ASN A ND2 1 ATOM 3279 N N . LEU A 1 427 ? 4.823 38.455 40.163 1.00 12.60 ? 423 LEU A N 1 ATOM 3280 C CA . LEU A 1 427 ? 4.929 37.184 39.473 1.00 12.95 ? 423 LEU A CA 1 ATOM 3281 C C . LEU A 1 427 ? 6.375 36.640 39.596 1.00 12.07 ? 423 LEU A C 1 ATOM 3282 O O . LEU A 1 427 ? 6.576 35.425 39.800 1.00 12.59 ? 423 LEU A O 1 ATOM 3283 C CB . LEU A 1 427 ? 4.540 37.383 37.995 1.00 13.07 ? 423 LEU A CB 1 ATOM 3284 C CG . LEU A 1 427 ? 4.402 36.082 37.243 1.00 15.26 ? 423 LEU A CG 1 ATOM 3285 C CD1 . LEU A 1 427 ? 3.314 35.203 37.807 1.00 19.90 ? 423 LEU A CD1 1 ATOM 3286 C CD2 . LEU A 1 427 ? 4.113 36.378 35.774 1.00 20.04 ? 423 LEU A CD2 1 ATOM 3287 N N . GLY A 1 428 ? 7.372 37.515 39.407 1.00 13.41 ? 424 GLY A N 1 ATOM 3288 C CA . GLY A 1 428 ? 8.784 37.041 39.543 1.00 13.85 ? 424 GLY A CA 1 ATOM 3289 C C . GLY A 1 428 ? 9.056 36.397 40.901 1.00 13.28 ? 424 GLY A C 1 ATOM 3290 O O . GLY A 1 428 ? 9.700 35.379 40.994 1.00 13.15 ? 424 GLY A O 1 ATOM 3291 N N . TYR A 1 429 ? 8.554 37.037 41.961 1.00 13.39 ? 425 TYR A N 1 ATOM 3292 C CA . TYR A 1 429 ? 8.805 36.493 43.316 1.00 12.47 ? 425 TYR A CA 1 ATOM 3293 C C . TYR A 1 429 ? 8.150 35.126 43.457 1.00 13.30 ? 425 TYR A C 1 ATOM 3294 O O . TYR A 1 429 ? 8.677 34.229 44.130 1.00 14.37 ? 425 TYR A O 1 ATOM 3295 C CB . TYR A 1 429 ? 8.276 37.468 44.395 1.00 13.46 ? 425 TYR A CB 1 ATOM 3296 C CG . TYR A 1 429 ? 9.184 38.647 44.654 1.00 12.97 ? 425 TYR A CG 1 ATOM 3297 C CD1 . TYR A 1 429 ? 10.291 38.948 43.854 1.00 16.14 ? 425 TYR A CD1 1 ATOM 3298 C CD2 . TYR A 1 429 ? 8.880 39.449 45.739 1.00 13.73 ? 425 TYR A CD2 1 ATOM 3299 C CE1 . TYR A 1 429 ? 11.097 40.064 44.173 1.00 16.94 ? 425 TYR A CE1 1 ATOM 3300 C CE2 . TYR A 1 429 ? 9.676 40.568 46.051 1.00 19.35 ? 425 TYR A CE2 1 ATOM 3301 C CZ . TYR A 1 429 ? 10.763 40.847 45.286 1.00 18.23 ? 425 TYR A CZ 1 ATOM 3302 O OH . TYR A 1 429 ? 11.507 41.956 45.635 1.00 22.34 ? 425 TYR A OH 1 ATOM 3303 N N . GLN A 1 430 ? 6.953 34.969 42.862 1.00 13.20 ? 426 GLN A N 1 ATOM 3304 C CA . GLN A 1 430 ? 6.254 33.696 43.089 1.00 13.38 ? 426 GLN A CA 1 ATOM 3305 C C . GLN A 1 430 ? 6.863 32.572 42.267 1.00 12.88 ? 426 GLN A C 1 ATOM 3306 O O . GLN A 1 430 ? 6.644 31.417 42.570 1.00 13.30 ? 426 GLN A O 1 ATOM 3307 C CB . GLN A 1 430 ? 4.739 33.843 42.877 1.00 17.99 ? 426 GLN A CB 1 ATOM 3308 C CG . GLN A 1 430 ? 4.272 33.907 41.551 1.00 20.83 ? 426 GLN A CG 1 ATOM 3309 C CD . GLN A 1 430 ? 2.705 34.041 41.531 1.00 20.46 ? 426 GLN A CD 1 ATOM 3310 O OE1 . GLN A 1 430 ? 2.136 34.912 42.212 1.00 19.91 ? 426 GLN A OE1 1 ATOM 3311 N NE2 . GLN A 1 430 ? 2.049 33.238 40.695 1.00 14.06 ? 426 GLN A NE2 1 ATOM 3312 N N . CYS A 1 431 ? 7.667 32.911 41.252 1.00 11.86 ? 427 CYS A N 1 ATOM 3313 C CA . CYS A 1 431 ? 8.381 31.888 40.442 1.00 11.69 ? 427 CYS A CA 1 ATOM 3314 C C . CYS A 1 431 ? 9.769 31.538 41.007 1.00 12.15 ? 427 CYS A C 1 ATOM 3315 O O . CYS A 1 431 ? 10.252 30.423 40.828 1.00 12.37 ? 427 CYS A O 1 ATOM 3316 C CB . CYS A 1 431 ? 8.544 32.387 38.979 1.00 11.64 ? 427 CYS A CB 1 ATOM 3317 S SG . CYS A 1 431 ? 6.937 32.444 38.096 1.00 14.27 ? 427 CYS A SG 1 ATOM 3318 N N . GLY A 1 432 ? 10.412 32.512 41.634 1.00 13.07 ? 428 GLY A N 1 ATOM 3319 C CA . GLY A 1 432 ? 11.795 32.255 42.129 1.00 13.68 ? 428 GLY A CA 1 ATOM 3320 C C . GLY A 1 432 ? 12.849 32.158 41.038 1.00 12.74 ? 428 GLY A C 1 ATOM 3321 O O . GLY A 1 432 ? 12.671 32.607 39.895 1.00 13.46 ? 428 GLY A O 1 ATOM 3322 N N . GLY A 1 433 ? 13.981 31.574 41.429 1.00 12.62 ? 429 GLY A N 1 ATOM 3323 C CA . GLY A 1 433 ? 15.110 31.533 40.512 1.00 12.61 ? 429 GLY A CA 1 ATOM 3324 C C . GLY A 1 433 ? 14.826 30.638 39.305 1.00 12.25 ? 429 GLY A C 1 ATOM 3325 O O . GLY A 1 433 ? 13.767 29.951 39.209 1.00 12.78 ? 429 GLY A O 1 ATOM 3326 N N . TRP A 1 434 ? 15.721 30.733 38.313 1.00 12.78 ? 430 TRP A N 1 ATOM 3327 C CA . TRP A 1 434 ? 15.587 29.972 37.047 1.00 12.46 ? 430 TRP A CA 1 ATOM 3328 C C . TRP A 1 434 ? 14.242 30.338 36.452 1.00 13.10 ? 430 TRP A C 1 ATOM 3329 O O . TRP A 1 434 ? 13.479 29.457 36.057 1.00 13.11 ? 430 TRP A O 1 ATOM 3330 C CB . TRP A 1 434 ? 15.657 28.459 37.236 1.00 12.90 ? 430 TRP A CB 1 ATOM 3331 C CG . TRP A 1 434 ? 17.011 27.943 37.633 1.00 13.26 ? 430 TRP A CG 1 ATOM 3332 C CD1 . TRP A 1 434 ? 17.336 27.349 38.820 1.00 13.73 ? 430 TRP A CD1 1 ATOM 3333 C CD2 . TRP A 1 434 ? 18.172 27.859 36.798 1.00 12.89 ? 430 TRP A CD2 1 ATOM 3334 N NE1 . TRP A 1 434 ? 18.662 26.962 38.811 1.00 14.99 ? 430 TRP A NE1 1 ATOM 3335 C CE2 . TRP A 1 434 ? 19.202 27.257 37.591 1.00 12.56 ? 430 TRP A CE2 1 ATOM 3336 C CE3 . TRP A 1 434 ? 18.452 28.266 35.457 1.00 13.34 ? 430 TRP A CE3 1 ATOM 3337 C CZ2 . TRP A 1 434 ? 20.515 27.009 37.089 1.00 14.71 ? 430 TRP A CZ2 1 ATOM 3338 C CZ3 . TRP A 1 434 ? 19.750 28.029 34.956 1.00 12.63 ? 430 TRP A CZ3 1 ATOM 3339 C CH2 . TRP A 1 434 ? 20.757 27.408 35.779 1.00 14.07 ? 430 TRP A CH2 1 ATOM 3340 N N . THR A 1 435 ? 13.959 31.636 36.381 1.00 12.57 ? 431 THR A N 1 ATOM 3341 C CA . THR A 1 435 ? 12.702 32.059 35.665 1.00 12.28 ? 431 THR A CA 1 ATOM 3342 C C . THR A 1 435 ? 13.044 33.332 34.906 1.00 12.55 ? 431 THR A C 1 ATOM 3343 O O . THR A 1 435 ? 13.294 34.386 35.559 1.00 12.84 ? 431 THR A O 1 ATOM 3344 C CB . THR A 1 435 ? 11.553 32.356 36.651 1.00 12.10 ? 431 THR A CB 1 ATOM 3345 O OG1 . THR A 1 435 ? 11.402 31.223 37.550 1.00 12.53 ? 431 THR A OG1 1 ATOM 3346 C CG2 . THR A 1 435 ? 10.244 32.495 35.873 1.00 12.66 ? 431 THR A CG2 1 ATOM 3347 N N . ILE A 1 436 ? 13.100 33.201 33.566 1.00 11.86 ? 432 ILE A N 1 ATOM 3348 C CA . ILE A 1 436 ? 13.432 34.265 32.587 1.00 12.82 ? 432 ILE A CA 1 ATOM 3349 C C . ILE A 1 436 ? 14.911 34.643 32.660 1.00 13.80 ? 432 ILE A C 1 ATOM 3350 O O . ILE A 1 436 ? 15.632 34.586 31.638 1.00 15.27 ? 432 ILE A O 1 ATOM 3351 C CB . ILE A 1 436 ? 12.523 35.483 32.706 1.00 12.51 ? 432 ILE A CB 1 ATOM 3352 C CG1 . ILE A 1 436 ? 11.029 35.117 32.540 1.00 14.34 ? 432 ILE A CG1 1 ATOM 3353 C CG2 . ILE A 1 436 ? 12.912 36.551 31.660 1.00 13.08 ? 432 ILE A CG2 1 ATOM 3354 C CD1 . ILE A 1 436 ? 10.698 34.386 31.177 1.00 14.61 ? 432 ILE A CD1 1 ATOM 3355 N N . GLU A 1 437 ? 15.353 35.025 33.845 1.00 13.30 ? 433 GLU A N 1 ATOM 3356 C CA . GLU A 1 437 ? 16.787 35.209 34.135 1.00 13.89 ? 433 GLU A CA 1 ATOM 3357 C C . GLU A 1 437 ? 17.290 34.062 34.947 1.00 13.86 ? 433 GLU A C 1 ATOM 3358 O O . GLU A 1 437 ? 16.534 33.343 35.648 1.00 14.33 ? 433 GLU A O 1 ATOM 3359 C CB . GLU A 1 437 ? 16.979 36.501 34.919 1.00 15.24 ? 433 GLU A CB 1 ATOM 3360 C CG . GLU A 1 437 ? 16.518 37.712 34.090 1.00 18.29 ? 433 GLU A CG 1 ATOM 3361 C CD . GLU A 1 437 ? 17.405 38.075 32.889 1.00 25.69 ? 433 GLU A CD 1 ATOM 3362 O OE1 . GLU A 1 437 ? 18.486 37.496 32.637 1.00 28.11 ? 433 GLU A OE1 1 ATOM 3363 O OE2 . GLU A 1 437 ? 16.976 38.999 32.165 1.00 35.00 ? 433 GLU A OE2 1 ATOM 3364 N N . TRP A 1 438 ? 18.615 33.885 34.932 1.00 12.73 ? 434 TRP A N 1 ATOM 3365 C CA . TRP A 1 438 ? 19.252 32.864 35.785 1.00 13.34 ? 434 TRP A CA 1 ATOM 3366 C C . TRP A 1 438 ? 18.834 32.939 37.243 1.00 13.61 ? 434 TRP A C 1 ATOM 3367 O O . TRP A 1 438 ? 18.386 31.935 37.828 1.00 14.21 ? 434 TRP A O 1 ATOM 3368 C CB . TRP A 1 438 ? 20.785 33.005 35.651 1.00 13.05 ? 434 TRP A CB 1 ATOM 3369 C CG . TRP A 1 438 ? 21.606 32.067 36.495 1.00 14.33 ? 434 TRP A CG 1 ATOM 3370 C CD1 . TRP A 1 438 ? 21.439 30.714 36.663 1.00 12.77 ? 434 TRP A CD1 1 ATOM 3371 C CD2 . TRP A 1 438 ? 22.787 32.425 37.219 1.00 15.00 ? 434 TRP A CD2 1 ATOM 3372 N NE1 . TRP A 1 438 ? 22.466 30.208 37.460 1.00 17.11 ? 434 TRP A NE1 1 ATOM 3373 C CE2 . TRP A 1 438 ? 23.280 31.252 37.820 1.00 16.49 ? 434 TRP A CE2 1 ATOM 3374 C CE3 . TRP A 1 438 ? 23.463 33.636 37.425 1.00 16.53 ? 434 TRP A CE3 1 ATOM 3375 C CZ2 . TRP A 1 438 ? 24.421 31.244 38.636 1.00 16.75 ? 434 TRP A CZ2 1 ATOM 3376 C CZ3 . TRP A 1 438 ? 24.618 33.626 38.256 1.00 14.50 ? 434 TRP A CZ3 1 ATOM 3377 C CH2 . TRP A 1 438 ? 25.071 32.449 38.825 1.00 15.39 ? 434 TRP A CH2 1 ATOM 3378 N N . GLN A 1 439 ? 18.953 34.139 37.836 1.00 13.87 ? 435 GLN A N 1 ATOM 3379 C CA . GLN A 1 439 ? 18.636 34.354 39.252 1.00 15.29 ? 435 GLN A CA 1 ATOM 3380 C C . GLN A 1 439 ? 17.166 34.666 39.495 1.00 15.22 ? 435 GLN A C 1 ATOM 3381 O O . GLN A 1 439 ? 16.798 35.064 40.601 1.00 17.02 ? 435 GLN A O 1 ATOM 3382 C CB . GLN A 1 439 ? 19.423 35.578 39.732 1.00 14.90 ? 435 GLN A CB 1 ATOM 3383 C CG . GLN A 1 439 ? 20.979 35.274 39.864 1.00 15.81 ? 435 GLN A CG 1 ATOM 3384 C CD . GLN A 1 439 ? 21.306 34.316 41.006 1.00 15.67 ? 435 GLN A CD 1 ATOM 3385 O OE1 . GLN A 1 439 ? 20.667 34.338 42.055 1.00 15.55 ? 435 GLN A OE1 1 ATOM 3386 N NE2 . GLN A 1 439 ? 22.294 33.465 40.806 1.00 15.89 ? 435 GLN A NE2 1 ATOM 3387 N N . GLY A 1 440 ? 16.322 34.474 38.485 1.00 15.40 ? 436 GLY A N 1 ATOM 3388 C CA . GLY A 1 440 ? 14.950 35.003 38.519 1.00 14.30 ? 436 GLY A CA 1 ATOM 3389 C C . GLY A 1 440 ? 14.964 36.535 38.557 1.00 16.25 ? 436 GLY A C 1 ATOM 3390 O O . GLY A 1 440 ? 16.004 37.187 38.308 1.00 16.27 ? 436 GLY A O 1 ATOM 3391 N N . ASP A 1 441 ? 13.805 37.125 38.846 1.00 14.64 ? 437 ASP A N 1 ATOM 3392 C CA . ASP A 1 441 ? 13.673 38.582 38.715 1.00 14.76 ? 437 ASP A CA 1 ATOM 3393 C C . ASP A 1 441 ? 12.400 39.008 39.428 1.00 15.57 ? 437 ASP A C 1 ATOM 3394 O O . ASP A 1 441 ? 11.654 38.153 39.949 1.00 14.56 ? 437 ASP A O 1 ATOM 3395 C CB . ASP A 1 441 ? 13.655 38.991 37.223 1.00 15.59 ? 437 ASP A CB 1 ATOM 3396 C CG . ASP A 1 441 ? 13.971 40.501 36.971 1.00 18.73 ? 437 ASP A CG 1 ATOM 3397 O OD1 . ASP A 1 441 ? 14.300 41.292 37.900 1.00 19.43 ? 437 ASP A OD1 1 ATOM 3398 O OD2 . ASP A 1 441 ? 13.941 40.823 35.752 1.00 22.12 ? 437 ASP A OD2 1 ATOM 3399 N N . THR A 1 442 ? 12.200 40.333 39.505 1.00 15.40 ? 438 THR A N 1 ATOM 3400 C CA . THR A 1 442 ? 11.064 40.920 40.199 1.00 16.12 ? 438 THR A CA 1 ATOM 3401 C C . THR A 1 442 ? 10.021 41.431 39.203 1.00 15.72 ? 438 THR A C 1 ATOM 3402 O O . THR A 1 442 ? 10.370 41.955 38.114 1.00 17.98 ? 438 THR A O 1 ATOM 3403 C CB . THR A 1 442 ? 11.526 42.051 41.152 1.00 16.76 ? 438 THR A CB 1 ATOM 3404 O OG1 . THR A 1 442 ? 10.390 42.565 41.829 1.00 16.41 ? 438 THR A OG1 1 ATOM 3405 C CG2 . THR A 1 442 ? 12.175 43.201 40.351 1.00 19.38 ? 438 THR A CG2 1 ATOM 3406 N N . GLY A 1 443 ? 8.734 41.309 39.570 1.00 15.21 ? 439 GLY A N 1 ATOM 3407 C CA . GLY A 1 443 ? 7.634 41.935 38.806 1.00 16.50 ? 439 GLY A CA 1 ATOM 3408 C C . GLY A 1 443 ? 7.035 41.059 37.730 1.00 16.84 ? 439 GLY A C 1 ATOM 3409 O O . GLY A 1 443 ? 7.115 39.816 37.796 1.00 15.90 ? 439 GLY A O 1 ATOM 3410 N N . ARG A 1 444 ? 6.447 41.682 36.719 1.00 16.26 ? 440 ARG A N 1 ATOM 3411 C CA . ARG A 1 444 ? 5.692 40.929 35.721 1.00 17.60 ? 440 ARG A CA 1 ATOM 3412 C C . ARG A 1 444 ? 6.630 40.499 34.582 1.00 17.12 ? 440 ARG A C 1 ATOM 3413 O O . ARG A 1 444 ? 6.743 41.136 33.522 1.00 18.65 ? 440 ARG A O 1 ATOM 3414 C CB . ARG A 1 444 ? 4.509 41.789 35.233 1.00 19.16 ? 440 ARG A CB 1 ATOM 3415 C CG . ARG A 1 444 ? 3.658 41.074 34.181 1.00 22.97 ? 440 ARG A CG 1 ATOM 3416 C CD . ARG A 1 444 ? 2.208 41.521 34.198 1.00 33.13 ? 440 ARG A CD 1 ATOM 3417 N NE . ARG A 1 444 ? 1.521 40.330 34.706 1.00 40.76 ? 440 ARG A NE 1 ATOM 3418 C CZ . ARG A 1 444 ? 1.219 40.021 35.980 1.00 38.64 ? 440 ARG A CZ 1 ATOM 3419 N NH1 . ARG A 1 444 ? 1.430 40.872 37.042 1.00 32.89 ? 440 ARG A NH1 1 ATOM 3420 N NH2 . ARG A 1 444 ? 0.677 38.810 36.164 1.00 29.81 ? 440 ARG A NH2 1 ATOM 3421 N N . THR A 1 445 ? 7.357 39.424 34.842 1.00 16.80 ? 441 THR A N 1 ATOM 3422 C CA . THR A 1 445 ? 8.450 39.034 33.976 1.00 16.86 ? 441 THR A CA 1 ATOM 3423 C C . THR A 1 445 ? 8.038 38.089 32.852 1.00 15.23 ? 441 THR A C 1 ATOM 3424 O O . THR A 1 445 ? 8.807 37.860 31.905 1.00 16.59 ? 441 THR A O 1 ATOM 3425 C CB . THR A 1 445 ? 9.542 38.323 34.776 1.00 18.45 ? 441 THR A CB 1 ATOM 3426 O OG1 . THR A 1 445 ? 8.939 37.209 35.451 1.00 18.03 ? 441 THR A OG1 1 ATOM 3427 C CG2 . THR A 1 445 ? 10.094 39.239 35.871 1.00 21.69 ? 441 THR A CG2 1 ATOM 3428 N N . THR A 1 446 ? 6.819 37.559 32.968 1.00 14.30 ? 442 THR A N 1 ATOM 3429 C CA . THR A 1 446 ? 6.290 36.618 31.977 1.00 13.59 ? 442 THR A CA 1 ATOM 3430 C C . THR A 1 446 ? 4.763 36.608 32.088 1.00 13.97 ? 442 THR A C 1 ATOM 3431 O O . THR A 1 446 ? 4.191 37.521 32.678 1.00 15.28 ? 442 THR A O 1 ATOM 3432 C CB . THR A 1 446 ? 6.938 35.209 32.164 1.00 13.09 ? 442 THR A CB 1 ATOM 3433 O OG1 . THR A 1 446 ? 6.562 34.353 31.085 1.00 14.41 ? 442 THR A OG1 1 ATOM 3434 C CG2 . THR A 1 446 ? 6.549 34.555 33.488 1.00 14.55 ? 442 THR A CG2 1 ATOM 3435 N N . VAL A 1 447 ? 4.125 35.656 31.400 1.00 13.34 ? 443 VAL A N 1 ATOM 3436 C CA . VAL A 1 447 ? 2.655 35.552 31.425 1.00 13.12 ? 443 VAL A CA 1 ATOM 3437 C C . VAL A 1 447 ? 2.275 34.682 32.614 1.00 14.01 ? 443 VAL A C 1 ATOM 3438 O O . VAL A 1 447 ? 2.736 33.536 32.747 1.00 15.49 ? 443 VAL A O 1 ATOM 3439 C CB . VAL A 1 447 ? 2.187 34.937 30.101 1.00 13.20 ? 443 VAL A CB 1 ATOM 3440 C CG1 . VAL A 1 447 ? 0.667 34.737 30.111 1.00 15.05 ? 443 VAL A CG1 1 ATOM 3441 C CG2 . VAL A 1 447 ? 2.624 35.853 28.942 1.00 16.24 ? 443 VAL A CG2 1 ATOM 3442 N N . GLY A 1 448 ? 1.367 35.182 33.455 1.00 13.50 ? 444 GLY A N 1 ATOM 3443 C CA . GLY A 1 448 ? 0.897 34.356 34.552 1.00 13.79 ? 444 GLY A CA 1 ATOM 3444 C C . GLY A 1 448 ? -0.115 35.116 35.367 1.00 14.78 ? 444 GLY A C 1 ATOM 3445 O O . GLY A 1 448 ? -0.593 36.193 34.937 1.00 16.55 ? 444 GLY A O 1 ATOM 3446 N N . THR A 1 449 ? -0.386 34.579 36.552 1.00 14.55 ? 445 THR A N 1 ATOM 3447 C CA . THR A 1 449 ? -1.431 35.145 37.423 1.00 13.18 ? 445 THR A CA 1 ATOM 3448 C C . THR A 1 449 ? -0.845 35.254 38.814 1.00 12.25 ? 445 THR A C 1 ATOM 3449 O O . THR A 1 449 ? -0.487 34.237 39.429 1.00 12.82 ? 445 THR A O 1 ATOM 3450 C CB . THR A 1 449 ? -2.672 34.187 37.430 1.00 13.25 ? 445 THR A CB 1 ATOM 3451 O OG1 . THR A 1 449 ? -3.163 34.049 36.064 1.00 15.92 ? 445 THR A OG1 1 ATOM 3452 C CG2 . THR A 1 449 ? -3.781 34.765 38.320 1.00 13.91 ? 445 THR A CG2 1 ATOM 3453 N N . THR A 1 450 ? -0.792 36.475 39.354 1.00 12.30 ? 446 THR A N 1 ATOM 3454 C CA . THR A 1 450 ? -0.256 36.668 40.702 1.00 12.11 ? 446 THR A CA 1 ATOM 3455 C C . THR A 1 450 ? -1.339 36.297 41.727 1.00 12.90 ? 446 THR A C 1 ATOM 3456 O O . THR A 1 450 ? -2.479 36.018 41.378 1.00 14.12 ? 446 THR A O 1 ATOM 3457 C CB . THR A 1 450 ? 0.102 38.170 40.959 1.00 12.99 ? 446 THR A CB 1 ATOM 3458 O OG1 . THR A 1 450 ? -1.103 38.933 40.833 1.00 13.33 ? 446 THR A OG1 1 ATOM 3459 C CG2 . THR A 1 450 ? 1.163 38.643 39.927 1.00 14.01 ? 446 THR A CG2 1 ATOM 3460 N N . ILE A 1 451 ? -0.959 36.241 43.004 1.00 13.29 ? 447 ILE A N 1 ATOM 3461 C CA . ILE A 1 451 ? -1.915 35.916 44.039 1.00 12.34 ? 447 ILE A CA 1 ATOM 3462 C C . ILE A 1 451 ? -3.041 36.940 44.051 1.00 12.93 ? 447 ILE A C 1 ATOM 3463 O O . ILE A 1 451 ? -4.207 36.576 44.179 1.00 13.30 ? 447 ILE A O 1 ATOM 3464 C CB . ILE A 1 451 ? -1.224 35.792 45.397 1.00 12.99 ? 447 ILE A CB 1 ATOM 3465 C CG1 . ILE A 1 451 ? -0.350 34.536 45.382 1.00 14.33 ? 447 ILE A CG1 1 ATOM 3466 C CG2 . ILE A 1 451 ? -2.307 35.672 46.547 1.00 14.64 ? 447 ILE A CG2 1 ATOM 3467 C CD1 . ILE A 1 451 ? 0.666 34.503 46.602 1.00 16.14 ? 447 ILE A CD1 1 ATOM 3468 N N . LEU A 1 452 ? -2.705 38.220 43.916 1.00 12.58 ? 448 LEU A N 1 ATOM 3469 C CA . LEU A 1 452 ? -3.760 39.247 43.867 1.00 14.10 ? 448 LEU A CA 1 ATOM 3470 C C . LEU A 1 452 ? -4.723 39.034 42.703 1.00 13.97 ? 448 LEU A C 1 ATOM 3471 O O . LEU A 1 452 ? -5.970 39.104 42.885 1.00 13.63 ? 448 LEU A O 1 ATOM 3472 C CB . LEU A 1 452 ? -3.142 40.634 43.721 1.00 14.75 ? 448 LEU A CB 1 ATOM 3473 C CG . LEU A 1 452 ? -4.099 41.811 43.469 1.00 14.27 ? 448 LEU A CG 1 ATOM 3474 C CD1 . LEU A 1 452 ? -4.980 42.002 44.688 1.00 16.95 ? 448 LEU A CD1 1 ATOM 3475 C CD2 . LEU A 1 452 ? -3.324 43.088 43.222 1.00 15.82 ? 448 LEU A CD2 1 ATOM 3476 N N . GLU A 1 453 ? -4.182 38.816 41.509 1.00 13.83 ? 449 GLU A N 1 ATOM 3477 C CA . GLU A 1 453 ? -5.050 38.537 40.336 1.00 13.38 ? 449 GLU A CA 1 ATOM 3478 C C . GLU A 1 453 ? -5.906 37.309 40.549 1.00 13.58 ? 449 GLU A C 1 ATOM 3479 O O . GLU A 1 453 ? -7.082 37.285 40.119 1.00 15.03 ? 449 GLU A O 1 ATOM 3480 C CB . GLU A 1 453 ? -4.147 38.381 39.095 1.00 14.97 ? 449 GLU A CB 1 ATOM 3481 C CG . GLU A 1 453 ? -3.498 39.738 38.706 1.00 17.64 ? 449 GLU A CG 1 ATOM 3482 C CD . GLU A 1 453 ? -2.216 39.606 37.827 1.00 26.14 ? 449 GLU A CD 1 ATOM 3483 O OE1 . GLU A 1 453 ? -1.706 38.518 37.458 1.00 18.16 ? 449 GLU A OE1 1 ATOM 3484 O OE2 . GLU A 1 453 ? -1.636 40.686 37.520 1.00 32.08 ? 449 GLU A OE2 1 ATOM 3485 N N . ALA A 1 454 ? -5.354 36.285 41.212 1.00 12.35 ? 450 ALA A N 1 ATOM 3486 C CA . ALA A 1 454 ? -6.058 35.025 41.468 1.00 12.71 ? 450 ALA A CA 1 ATOM 3487 C C . ALA A 1 454 ? -7.209 35.289 42.451 1.00 13.04 ? 450 ALA A C 1 ATOM 3488 O O . ALA A 1 454 ? -8.323 34.794 42.267 1.00 14.40 ? 450 ALA A O 1 ATOM 3489 C CB . ALA A 1 454 ? -5.088 33.997 42.048 1.00 14.20 ? 450 ALA A CB 1 ATOM 3490 N N . VAL A 1 455 ? -6.952 36.106 43.466 1.00 13.68 ? 451 VAL A N 1 ATOM 3491 C CA . VAL A 1 455 ? -8.031 36.487 44.420 1.00 14.09 ? 451 VAL A CA 1 ATOM 3492 C C . VAL A 1 455 ? -9.160 37.207 43.675 1.00 14.57 ? 451 VAL A C 1 ATOM 3493 O O . VAL A 1 455 ? -10.366 36.885 43.851 1.00 14.25 ? 451 VAL A O 1 ATOM 3494 C CB . VAL A 1 455 ? -7.477 37.382 45.546 1.00 13.12 ? 451 VAL A CB 1 ATOM 3495 C CG1 . VAL A 1 455 ? -8.704 37.982 46.444 1.00 15.14 ? 451 VAL A CG1 1 ATOM 3496 C CG2 . VAL A 1 455 ? -6.581 36.515 46.453 1.00 15.46 ? 451 VAL A CG2 1 ATOM 3497 N N . LYS A 1 456 ? -8.805 38.164 42.813 1.00 14.34 ? 452 LYS A N 1 ATOM 3498 C CA . LYS A 1 456 ? -9.831 38.941 42.092 1.00 15.60 ? 452 LYS A CA 1 ATOM 3499 C C . LYS A 1 456 ? -10.615 38.025 41.166 1.00 16.22 ? 452 LYS A C 1 ATOM 3500 O O . LYS A 1 456 ? -11.823 38.268 40.930 1.00 18.30 ? 452 LYS A O 1 ATOM 3501 C CB . LYS A 1 456 ? -9.196 40.087 41.278 1.00 15.11 ? 452 LYS A CB 1 ATOM 3502 C CG . LYS A 1 456 ? -8.616 41.207 42.160 1.00 18.67 ? 452 LYS A CG 1 ATOM 3503 C CD . LYS A 1 456 ? -7.917 42.213 41.268 1.00 22.73 ? 452 LYS A CD 1 ATOM 3504 C CE . LYS A 1 456 ? -7.378 43.336 42.122 1.00 29.21 ? 452 LYS A CE 1 ATOM 3505 N NZ . LYS A 1 456 ? -6.773 44.383 41.240 1.00 33.97 ? 452 LYS A NZ 1 ATOM 3506 N N . ALA A 1 457 ? -9.963 36.967 40.669 1.00 15.61 ? 453 ALA A N 1 ATOM 3507 C CA . ALA A 1 457 ? -10.628 36.045 39.737 1.00 16.57 ? 453 ALA A CA 1 ATOM 3508 C C . ALA A 1 457 ? -11.520 35.073 40.478 1.00 18.02 ? 453 ALA A C 1 ATOM 3509 O O . ALA A 1 457 ? -12.352 34.408 39.844 1.00 20.41 ? 453 ALA A O 1 ATOM 3510 C CB . ALA A 1 457 ? -9.561 35.300 38.925 1.00 15.77 ? 453 ALA A CB 1 ATOM 3511 N N . ALA A 1 458 ? -11.334 34.920 41.802 1.00 15.28 ? 454 ALA A N 1 ATOM 3512 C CA . ALA A 1 458 ? -12.043 33.887 42.574 1.00 15.75 ? 454 ALA A CA 1 ATOM 3513 C C . ALA A 1 458 ? -13.275 34.436 43.291 1.00 16.10 ? 454 ALA A C 1 ATOM 3514 O O . ALA A 1 458 ? -14.264 33.711 43.459 1.00 17.72 ? 454 ALA A O 1 ATOM 3515 C CB . ALA A 1 458 ? -11.094 33.285 43.621 1.00 16.66 ? 454 ALA A CB 1 ATOM 3516 N N . VAL A 1 459 ? -13.172 35.674 43.756 1.00 15.68 ? 455 VAL A N 1 ATOM 3517 C CA . VAL A 1 459 ? -14.214 36.126 44.680 1.00 15.41 ? 455 VAL A CA 1 ATOM 3518 C C . VAL A 1 459 ? -15.528 36.485 44.000 1.00 15.87 ? 455 VAL A C 1 ATOM 3519 O O . VAL A 1 459 ? -15.579 36.794 42.805 1.00 16.75 ? 455 VAL A O 1 ATOM 3520 C CB . VAL A 1 459 ? -13.729 37.291 45.546 1.00 15.25 ? 455 VAL A CB 1 ATOM 3521 C CG1 . VAL A 1 459 ? -12.590 36.798 46.502 1.00 16.52 ? 455 VAL A CG1 1 ATOM 3522 C CG2 . VAL A 1 459 ? -13.362 38.525 44.689 1.00 15.79 ? 455 VAL A CG2 1 ATOM 3523 N N . ASP A 1 460 ? -16.613 36.481 44.797 1.00 16.74 ? 456 ASP A N 1 ATOM 3524 C CA . ASP A 1 460 ? -17.932 36.946 44.289 1.00 18.28 ? 456 ASP A CA 1 ATOM 3525 C C . ASP A 1 460 ? -17.827 38.352 43.701 1.00 17.69 ? 456 ASP A C 1 ATOM 3526 O O . ASP A 1 460 ? -17.030 39.202 44.159 1.00 16.34 ? 456 ASP A O 1 ATOM 3527 C CB . ASP A 1 460 ? -18.894 36.978 45.500 1.00 17.87 ? 456 ASP A CB 1 ATOM 3528 C CG . ASP A 1 460 ? -20.359 37.205 45.118 1.00 24.85 ? 456 ASP A CG 1 ATOM 3529 O OD1 . ASP A 1 460 ? -20.872 38.365 45.033 1.00 25.75 ? 456 ASP A OD1 1 ATOM 3530 O OD2 . ASP A 1 460 ? -21.023 36.165 44.906 1.00 29.45 ? 456 ASP A OD2 1 ATOM 3531 N N . PRO A 1 461 ? -18.650 38.695 42.710 1.00 17.98 ? 457 PRO A N 1 ATOM 3532 C CA . PRO A 1 461 ? -18.596 40.062 42.169 1.00 18.69 ? 457 PRO A CA 1 ATOM 3533 C C . PRO A 1 461 ? -18.860 41.201 43.193 1.00 18.67 ? 457 PRO A C 1 ATOM 3534 O O . PRO A 1 461 ? -18.366 42.317 42.999 1.00 20.15 ? 457 PRO A O 1 ATOM 3535 C CB . PRO A 1 461 ? -19.661 40.062 41.021 1.00 20.25 ? 457 PRO A CB 1 ATOM 3536 C CG . PRO A 1 461 ? -20.446 38.900 41.269 1.00 19.31 ? 457 PRO A CG 1 ATOM 3537 C CD . PRO A 1 461 ? -19.592 37.842 41.962 1.00 18.54 ? 457 PRO A CD 1 ATOM 3538 N N . SER A 1 462 ? -19.609 40.905 44.248 1.00 19.10 ? 458 SER A N 1 ATOM 3539 C CA . SER A 1 462 ? -19.903 41.906 45.289 1.00 19.13 ? 458 SER A CA 1 ATOM 3540 C C . SER A 1 462 ? -18.743 42.122 46.253 1.00 19.56 ? 458 SER A C 1 ATOM 3541 O O . SER A 1 462 ? -18.760 43.101 47.031 1.00 21.24 ? 458 SER A O 1 ATOM 3542 C CB . SER A 1 462 ? -21.165 41.496 46.077 1.00 18.67 ? 458 SER A CB 1 ATOM 3543 O OG . SER A 1 462 ? -20.950 40.414 46.917 1.00 21.88 ? 458 SER A OG 1 ATOM 3544 N N . THR A 1 463 ? -17.716 41.281 46.173 1.00 18.12 ? 459 THR A N 1 ATOM 3545 C CA . THR A 1 463 ? -16.571 41.384 47.099 1.00 16.30 ? 459 THR A CA 1 ATOM 3546 C C . THR A 1 463 ? -15.571 42.431 46.615 1.00 16.78 ? 459 THR A C 1 ATOM 3547 O O . THR A 1 463 ? -15.008 42.330 45.525 1.00 17.76 ? 459 THR A O 1 ATOM 3548 C CB . THR A 1 463 ? -15.890 40.016 47.219 1.00 15.76 ? 459 THR A CB 1 ATOM 3549 O OG1 . THR A 1 463 ? -16.829 39.072 47.746 1.00 16.91 ? 459 THR A OG1 1 ATOM 3550 C CG2 . THR A 1 463 ? -14.652 40.124 48.152 1.00 17.29 ? 459 THR A CG2 1 ATOM 3551 N N . VAL A 1 464 ? -15.367 43.490 47.404 1.00 16.25 ? 460 VAL A N 1 ATOM 3552 C CA . VAL A 1 464 ? -14.410 44.524 47.010 1.00 17.34 ? 460 VAL A CA 1 ATOM 3553 C C . VAL A 1 464 ? -13.020 44.086 47.494 1.00 17.31 ? 460 VAL A C 1 ATOM 3554 O O . VAL A 1 464 ? -12.830 43.751 48.667 1.00 18.26 ? 460 VAL A O 1 ATOM 3555 C CB . VAL A 1 464 ? -14.759 45.861 47.645 1.00 17.39 ? 460 VAL A CB 1 ATOM 3556 C CG1 . VAL A 1 464 ? -13.689 46.917 47.355 1.00 18.32 ? 460 VAL A CG1 1 ATOM 3557 C CG2 . VAL A 1 464 ? -16.121 46.337 47.117 1.00 19.94 ? 460 VAL A CG2 1 ATOM 3558 N N . VAL A 1 465 ? -12.063 44.051 46.560 1.00 17.46 ? 461 VAL A N 1 ATOM 3559 C CA . VAL A 1 465 ? -10.681 43.628 46.886 1.00 17.27 ? 461 VAL A CA 1 ATOM 3560 C C . VAL A 1 465 ? -9.814 44.876 46.915 1.00 18.13 ? 461 VAL A C 1 ATOM 3561 O O . VAL A 1 465 ? -9.742 45.594 45.931 1.00 19.60 ? 461 VAL A O 1 ATOM 3562 C CB . VAL A 1 465 ? -10.176 42.664 45.799 1.00 16.68 ? 461 VAL A CB 1 ATOM 3563 C CG1 . VAL A 1 465 ? -8.715 42.204 46.147 1.00 18.07 ? 461 VAL A CG1 1 ATOM 3564 C CG2 . VAL A 1 465 ? -11.112 41.467 45.685 1.00 17.72 ? 461 VAL A CG2 1 ATOM 3565 N N . VAL A 1 466 ? -9.110 45.100 48.032 1.00 17.33 ? 462 VAL A N 1 ATOM 3566 C CA . VAL A 1 466 ? -8.168 46.220 48.147 1.00 17.26 ? 462 VAL A CA 1 ATOM 3567 C C . VAL A 1 466 ? -6.789 45.617 48.217 1.00 16.68 ? 462 VAL A C 1 ATOM 3568 O O . VAL A 1 466 ? -6.592 44.679 48.981 1.00 17.08 ? 462 VAL A O 1 ATOM 3569 C CB . VAL A 1 466 ? -8.428 46.969 49.452 1.00 17.73 ? 462 VAL A CB 1 ATOM 3570 C CG1 . VAL A 1 466 ? -7.356 48.073 49.714 1.00 19.55 ? 462 VAL A CG1 1 ATOM 3571 C CG2 . VAL A 1 466 ? -9.869 47.548 49.449 1.00 18.86 ? 462 VAL A CG2 1 ATOM 3572 N N . PHE A 1 467 ? -5.857 46.161 47.434 1.00 15.99 ? 463 PHE A N 1 ATOM 3573 C CA . PHE A 1 467 ? -4.475 45.756 47.507 1.00 15.57 ? 463 PHE A CA 1 ATOM 3574 C C . PHE A 1 467 ? -3.661 46.881 48.185 1.00 16.34 ? 463 PHE A C 1 ATOM 3575 O O . PHE A 1 467 ? -3.778 48.072 47.816 1.00 17.66 ? 463 PHE A O 1 ATOM 3576 C CB . PHE A 1 467 ? -3.894 45.504 46.124 1.00 16.65 ? 463 PHE A CB 1 ATOM 3577 C CG . PHE A 1 467 ? -2.409 45.291 46.124 1.00 18.07 ? 463 PHE A CG 1 ATOM 3578 C CD1 . PHE A 1 467 ? -1.835 44.215 46.811 1.00 17.10 ? 463 PHE A CD1 1 ATOM 3579 C CD2 . PHE A 1 467 ? -1.589 46.162 45.439 1.00 21.34 ? 463 PHE A CD2 1 ATOM 3580 C CE1 . PHE A 1 467 ? -0.433 44.017 46.796 1.00 18.94 ? 463 PHE A CE1 1 ATOM 3581 C CE2 . PHE A 1 467 ? -0.188 45.962 45.407 1.00 24.17 ? 463 PHE A CE2 1 ATOM 3582 C CZ . PHE A 1 467 ? 0.385 44.909 46.098 1.00 20.03 ? 463 PHE A CZ 1 ATOM 3583 N N . ALA A 1 468 ? -2.848 46.494 49.156 1.00 17.70 ? 464 ALA A N 1 ATOM 3584 C CA . ALA A 1 468 ? -1.848 47.413 49.716 1.00 17.32 ? 464 ALA A CA 1 ATOM 3585 C C . ALA A 1 468 ? -0.632 46.609 49.970 1.00 17.39 ? 464 ALA A C 1 ATOM 3586 O O . ALA A 1 468 ? -0.689 45.639 50.719 1.00 18.16 ? 464 ALA A O 1 ATOM 3587 C CB . ALA A 1 468 ? -2.356 48.061 51.037 1.00 17.94 ? 464 ALA A CB 1 ATOM 3588 N N . GLU A 1 469 ? 0.492 47.010 49.368 1.00 17.82 ? 465 GLU A N 1 ATOM 3589 C CA . GLU A 1 469 ? 1.689 46.221 49.508 1.00 18.75 ? 465 GLU A CA 1 ATOM 3590 C C . GLU A 1 469 ? 2.227 46.117 50.931 1.00 19.17 ? 465 GLU A C 1 ATOM 3591 O O . GLU A 1 469 ? 2.582 45.041 51.420 1.00 19.12 ? 465 GLU A O 1 ATOM 3592 C CB . GLU A 1 469 ? 2.777 46.739 48.548 1.00 19.53 ? 465 GLU A CB 1 ATOM 3593 C CG . GLU A 1 469 ? 4.009 45.831 48.632 1.00 23.49 ? 465 GLU A CG 1 ATOM 3594 C CD . GLU A 1 469 ? 5.074 46.170 47.615 1.00 28.09 ? 465 GLU A CD 1 ATOM 3595 O OE1 . GLU A 1 469 ? 4.757 46.764 46.543 1.00 29.75 ? 465 GLU A OE1 1 ATOM 3596 O OE2 . GLU A 1 469 ? 6.224 45.765 47.901 1.00 30.77 ? 465 GLU A OE2 1 ATOM 3597 N N . ASN A 1 470 ? 2.270 47.263 51.637 1.00 18.19 ? 466 ASN A N 1 ATOM 3598 C CA . ASN A 1 470 ? 2.788 47.279 53.003 1.00 19.50 ? 466 ASN A CA 1 ATOM 3599 C C . ASN A 1 470 ? 1.994 48.265 53.869 1.00 20.29 ? 466 ASN A C 1 ATOM 3600 O O . ASN A 1 470 ? 2.482 49.358 54.301 1.00 22.19 ? 466 ASN A O 1 ATOM 3601 C CB A ASN A 1 470 ? 4.235 47.727 52.942 0.50 20.14 ? 466 ASN A CB 1 ATOM 3602 C CB B ASN A 1 470 ? 4.276 47.645 53.086 0.50 18.80 ? 466 ASN A CB 1 ATOM 3603 C CG A ASN A 1 470 ? 4.936 47.536 54.233 0.50 21.43 ? 466 ASN A CG 1 ATOM 3604 C CG B ASN A 1 470 ? 5.178 46.595 52.485 0.50 17.47 ? 466 ASN A CG 1 ATOM 3605 O OD1 A ASN A 1 470 ? 5.940 48.217 54.521 0.50 28.90 ? 466 ASN A OD1 1 ATOM 3606 O OD1 B ASN A 1 470 ? 5.276 45.458 52.980 0.50 15.60 ? 466 ASN A OD1 1 ATOM 3607 N ND2 A ASN A 1 470 ? 4.424 46.616 55.057 0.50 22.27 ? 466 ASN A ND2 1 ATOM 3608 N ND2 B ASN A 1 470 ? 5.850 46.969 51.404 0.50 16.89 ? 466 ASN A ND2 1 ATOM 3609 N N . PRO A 1 471 ? 0.743 47.907 54.161 1.00 19.62 ? 467 PRO A N 1 ATOM 3610 C CA . PRO A 1 471 ? -0.118 48.802 54.931 1.00 20.36 ? 467 PRO A CA 1 ATOM 3611 C C . PRO A 1 471 ? 0.351 48.882 56.371 1.00 20.83 ? 467 PRO A C 1 ATOM 3612 O O . PRO A 1 471 ? 0.908 47.934 56.917 1.00 21.21 ? 467 PRO A O 1 ATOM 3613 C CB . PRO A 1 471 ? -1.507 48.121 54.850 1.00 20.27 ? 467 PRO A CB 1 ATOM 3614 C CG . PRO A 1 471 ? -1.152 46.617 54.731 1.00 19.27 ? 467 PRO A CG 1 ATOM 3615 C CD . PRO A 1 471 ? 0.113 46.610 53.842 1.00 19.42 ? 467 PRO A CD 1 ATOM 3616 N N . ASP A 1 472 ? 0.124 50.029 57.007 1.00 23.03 ? 468 ASP A N 1 ATOM 3617 C CA . ASP A 1 472 ? 0.388 50.073 58.422 1.00 23.49 ? 468 ASP A CA 1 ATOM 3618 C C . ASP A 1 472 ? -0.832 49.647 59.245 1.00 22.56 ? 468 ASP A C 1 ATOM 3619 O O . ASP A 1 472 ? -1.940 49.384 58.683 1.00 23.01 ? 468 ASP A O 1 ATOM 3620 C CB . ASP A 1 472 ? 0.924 51.445 58.842 1.00 24.29 ? 468 ASP A CB 1 ATOM 3621 C CG . ASP A 1 472 ? -0.091 52.576 58.690 1.00 28.36 ? 468 ASP A CG 1 ATOM 3622 O OD1 . ASP A 1 472 ? 0.367 53.746 58.752 1.00 31.88 ? 468 ASP A OD1 1 ATOM 3623 O OD2 . ASP A 1 472 ? -1.325 52.397 58.596 1.00 27.28 ? 468 ASP A OD2 1 ATOM 3624 N N . ALA A 1 473 ? -0.640 49.562 60.549 1.00 23.14 ? 469 ALA A N 1 ATOM 3625 C CA . ALA A 1 473 ? -1.624 48.944 61.408 1.00 22.78 ? 469 ALA A CA 1 ATOM 3626 C C . ALA A 1 473 ? -2.929 49.730 61.377 1.00 22.53 ? 469 ALA A C 1 ATOM 3627 O O . ALA A 1 473 ? -4.014 49.144 61.369 1.00 20.42 ? 469 ALA A O 1 ATOM 3628 C CB . ALA A 1 473 ? -1.098 48.823 62.833 1.00 23.95 ? 469 ALA A CB 1 ATOM 3629 N N . GLU A 1 474 ? -2.827 51.062 61.379 1.00 22.19 ? 470 GLU A N 1 ATOM 3630 C CA . GLU A 1 474 ? -4.025 51.868 61.346 1.00 22.40 ? 470 GLU A CA 1 ATOM 3631 C C . GLU A 1 474 ? -4.866 51.707 60.066 1.00 21.13 ? 470 GLU A C 1 ATOM 3632 O O . GLU A 1 474 ? -6.082 51.653 60.127 1.00 21.08 ? 470 GLU A O 1 ATOM 3633 C CB . GLU A 1 474 ? -3.643 53.348 61.567 1.00 24.90 ? 470 GLU A CB 1 ATOM 3634 C CG . GLU A 1 474 ? -4.852 54.238 61.602 1.00 28.67 ? 470 GLU A CG 1 ATOM 3635 C CD . GLU A 1 474 ? -4.524 55.740 61.518 1.00 35.23 ? 470 GLU A CD 1 ATOM 3636 O OE1 . GLU A 1 474 ? -5.433 56.484 61.065 1.00 34.61 ? 470 GLU A OE1 1 ATOM 3637 O OE2 . GLU A 1 474 ? -3.392 56.152 61.904 1.00 34.15 ? 470 GLU A OE2 1 ATOM 3638 N N . PHE A 1 475 ? -4.206 51.606 58.912 1.00 20.36 ? 471 PHE A N 1 ATOM 3639 C CA . PHE A 1 475 ? -4.876 51.370 57.634 1.00 20.55 ? 471 PHE A CA 1 ATOM 3640 C C . PHE A 1 475 ? -5.760 50.099 57.717 1.00 19.00 ? 471 PHE A C 1 ATOM 3641 O O . PHE A 1 475 ? -6.914 50.084 57.236 1.00 20.22 ? 471 PHE A O 1 ATOM 3642 C CB . PHE A 1 475 ? -3.834 51.189 56.524 1.00 20.04 ? 471 PHE A CB 1 ATOM 3643 C CG . PHE A 1 475 ? -4.418 50.893 55.172 1.00 22.87 ? 471 PHE A CG 1 ATOM 3644 C CD1 . PHE A 1 475 ? -4.706 49.576 54.818 1.00 22.32 ? 471 PHE A CD1 1 ATOM 3645 C CD2 . PHE A 1 475 ? -4.620 51.898 54.235 1.00 26.32 ? 471 PHE A CD2 1 ATOM 3646 C CE1 . PHE A 1 475 ? -5.227 49.269 53.563 1.00 25.17 ? 471 PHE A CE1 1 ATOM 3647 C CE2 . PHE A 1 475 ? -5.142 51.606 52.977 1.00 27.20 ? 471 PHE A CE2 1 ATOM 3648 C CZ . PHE A 1 475 ? -5.446 50.246 52.652 1.00 25.47 ? 471 PHE A CZ 1 ATOM 3649 N N . VAL A 1 476 ? -5.189 49.054 58.308 1.00 19.14 ? 472 VAL A N 1 ATOM 3650 C CA . VAL A 1 476 ? -5.888 47.788 58.359 1.00 17.75 ? 472 VAL A CA 1 ATOM 3651 C C . VAL A 1 476 ? -7.102 47.894 59.327 1.00 18.19 ? 472 VAL A C 1 ATOM 3652 O O . VAL A 1 476 ? -8.219 47.513 58.972 1.00 18.96 ? 472 VAL A O 1 ATOM 3653 C CB . VAL A 1 476 ? -4.974 46.665 58.784 1.00 17.77 ? 472 VAL A CB 1 ATOM 3654 C CG1 . VAL A 1 476 ? -5.789 45.346 58.821 1.00 17.80 ? 472 VAL A CG1 1 ATOM 3655 C CG2 . VAL A 1 476 ? -3.813 46.559 57.789 1.00 18.80 ? 472 VAL A CG2 1 ATOM 3656 N N . LYS A 1 477 ? -6.863 48.436 60.517 1.00 18.87 ? 473 LYS A N 1 ATOM 3657 C CA . LYS A 1 477 ? -7.904 48.528 61.555 1.00 20.51 ? 473 LYS A CA 1 ATOM 3658 C C . LYS A 1 477 ? -9.054 49.415 61.094 1.00 20.64 ? 473 LYS A C 1 ATOM 3659 O O . LYS A 1 477 ? -10.208 49.198 61.519 1.00 20.75 ? 473 LYS A O 1 ATOM 3660 C CB . LYS A 1 477 ? -7.351 49.119 62.865 1.00 21.68 ? 473 LYS A CB 1 ATOM 3661 C CG . LYS A 1 477 ? -6.490 48.117 63.636 1.00 25.55 ? 473 LYS A CG 1 ATOM 3662 C CD . LYS A 1 477 ? -5.755 48.812 64.797 1.00 33.92 ? 473 LYS A CD 1 ATOM 3663 C CE . LYS A 1 477 ? -5.188 47.790 65.773 1.00 41.81 ? 473 LYS A CE 1 ATOM 3664 N NZ . LYS A 1 477 ? -4.942 48.445 67.102 1.00 45.61 ? 473 LYS A NZ 1 ATOM 3665 N N . SER A 1 478 ? -8.739 50.424 60.278 1.00 19.90 ? 474 SER A N 1 ATOM 3666 C CA . SER A 1 478 ? -9.773 51.361 59.856 1.00 22.35 ? 474 SER A CA 1 ATOM 3667 C C . SER A 1 478 ? -10.483 50.967 58.564 1.00 21.86 ? 474 SER A C 1 ATOM 3668 O O . SER A 1 478 ? -11.425 51.657 58.118 1.00 22.62 ? 474 SER A O 1 ATOM 3669 C CB . SER A 1 478 ? -9.184 52.772 59.712 1.00 22.18 ? 474 SER A CB 1 ATOM 3670 O OG . SER A 1 478 ? -8.731 53.299 60.954 1.00 27.92 ? 474 SER A OG 1 ATOM 3671 N N . GLY A 1 479 ? -10.040 49.861 57.947 1.00 20.74 ? 475 GLY A N 1 ATOM 3672 C CA . GLY A 1 479 ? -10.452 49.569 56.588 1.00 20.44 ? 475 GLY A CA 1 ATOM 3673 C C . GLY A 1 479 ? -11.778 48.874 56.352 1.00 21.38 ? 475 GLY A C 1 ATOM 3674 O O . GLY A 1 479 ? -12.203 48.785 55.200 1.00 22.28 ? 475 GLY A O 1 ATOM 3675 N N . GLY A 1 480 ? -12.398 48.359 57.418 1.00 20.46 ? 476 GLY A N 1 ATOM 3676 C CA . GLY A 1 480 ? -13.650 47.616 57.313 1.00 21.38 ? 476 GLY A CA 1 ATOM 3677 C C . GLY A 1 480 ? -13.496 46.314 56.520 1.00 19.76 ? 476 GLY A C 1 ATOM 3678 O O . GLY A 1 480 ? -14.383 45.975 55.731 1.00 19.93 ? 476 GLY A O 1 ATOM 3679 N N . PHE A 1 481 ? -12.368 45.654 56.739 1.00 18.71 ? 477 PHE A N 1 ATOM 3680 C CA . PHE A 1 481 ? -12.051 44.377 56.045 1.00 17.74 ? 477 PHE A CA 1 ATOM 3681 C C . PHE A 1 481 ? -12.655 43.192 56.757 1.00 17.68 ? 477 PHE A C 1 ATOM 3682 O O . PHE A 1 481 ? -12.694 43.120 57.995 1.00 18.45 ? 477 PHE A O 1 ATOM 3683 C CB . PHE A 1 481 ? -10.542 44.194 55.940 1.00 16.28 ? 477 PHE A CB 1 ATOM 3684 C CG . PHE A 1 481 ? -9.865 45.258 55.129 1.00 16.20 ? 477 PHE A CG 1 ATOM 3685 C CD1 . PHE A 1 481 ? -10.173 45.394 53.771 1.00 15.18 ? 477 PHE A CD1 1 ATOM 3686 C CD2 . PHE A 1 481 ? -8.963 46.166 55.714 1.00 16.15 ? 477 PHE A CD2 1 ATOM 3687 C CE1 . PHE A 1 481 ? -9.564 46.381 52.986 1.00 17.52 ? 477 PHE A CE1 1 ATOM 3688 C CE2 . PHE A 1 481 ? -8.364 47.140 54.921 1.00 19.73 ? 477 PHE A CE2 1 ATOM 3689 C CZ . PHE A 1 481 ? -8.655 47.250 53.571 1.00 17.44 ? 477 PHE A CZ 1 ATOM 3690 N N . SER A 1 482 ? -13.139 42.225 55.972 1.00 16.73 ? 478 SER A N 1 ATOM 3691 C CA . SER A 1 482 ? -13.599 40.975 56.548 1.00 17.11 ? 478 SER A CA 1 ATOM 3692 C C . SER A 1 482 ? -12.468 40.016 56.951 1.00 16.22 ? 478 SER A C 1 ATOM 3693 O O . SER A 1 482 ? -12.561 39.245 57.944 1.00 17.82 ? 478 SER A O 1 ATOM 3694 C CB . SER A 1 482 ? -14.536 40.282 55.557 1.00 16.38 ? 478 SER A CB 1 ATOM 3695 O OG . SER A 1 482 ? -15.745 41.036 55.400 1.00 19.24 ? 478 SER A OG 1 ATOM 3696 N N . TYR A 1 483 ? -11.402 40.040 56.126 1.00 17.04 ? 479 TYR A N 1 ATOM 3697 C CA . TYR A 1 483 ? -10.193 39.213 56.353 1.00 16.19 ? 479 TYR A CA 1 ATOM 3698 C C . TYR A 1 483 ? -9.124 39.764 55.416 1.00 14.03 ? 479 TYR A C 1 ATOM 3699 O O . TYR A 1 483 ? -9.410 40.616 54.560 1.00 14.73 ? 479 TYR A O 1 ATOM 3700 C CB . TYR A 1 483 ? -10.450 37.694 56.088 1.00 17.57 ? 479 TYR A CB 1 ATOM 3701 C CG . TYR A 1 483 ? -10.994 37.376 54.718 1.00 17.62 ? 479 TYR A CG 1 ATOM 3702 C CD1 . TYR A 1 483 ? -10.120 37.270 53.610 1.00 18.22 ? 479 TYR A CD1 1 ATOM 3703 C CD2 . TYR A 1 483 ? -12.370 37.106 54.521 1.00 19.04 ? 479 TYR A CD2 1 ATOM 3704 C CE1 . TYR A 1 483 ? -10.626 36.995 52.319 1.00 18.72 ? 479 TYR A CE1 1 ATOM 3705 C CE2 . TYR A 1 483 ? -12.891 36.817 53.233 1.00 18.53 ? 479 TYR A CE2 1 ATOM 3706 C CZ . TYR A 1 483 ? -12.010 36.727 52.150 1.00 18.39 ? 479 TYR A CZ 1 ATOM 3707 O OH . TYR A 1 483 ? -12.457 36.462 50.869 1.00 19.60 ? 479 TYR A OH 1 ATOM 3708 N N . ALA A 1 484 ? -7.900 39.306 55.665 1.00 14.77 ? 480 ALA A N 1 ATOM 3709 C CA . ALA A 1 484 ? -6.775 39.635 54.800 1.00 15.48 ? 480 ALA A CA 1 ATOM 3710 C C . ALA A 1 484 ? -6.067 38.378 54.354 1.00 15.00 ? 480 ALA A C 1 ATOM 3711 O O . ALA A 1 484 ? -5.979 37.408 55.103 1.00 15.90 ? 480 ALA A O 1 ATOM 3712 C CB . ALA A 1 484 ? -5.806 40.543 55.542 1.00 16.14 ? 480 ALA A CB 1 ATOM 3713 N N . ILE A 1 485 ? -5.489 38.455 53.151 1.00 14.66 ? 481 ILE A N 1 ATOM 3714 C CA . ILE A 1 485 ? -4.518 37.457 52.659 1.00 15.10 ? 481 ILE A CA 1 ATOM 3715 C C . ILE A 1 485 ? -3.199 38.230 52.510 1.00 13.85 ? 481 ILE A C 1 ATOM 3716 O O . ILE A 1 485 ? -3.168 39.228 51.780 1.00 14.71 ? 481 ILE A O 1 ATOM 3717 C CB . ILE A 1 485 ? -4.972 36.901 51.316 1.00 15.31 ? 481 ILE A CB 1 ATOM 3718 C CG1 . ILE A 1 485 ? -6.249 36.077 51.519 1.00 16.58 ? 481 ILE A CG1 1 ATOM 3719 C CG2 . ILE A 1 485 ? -3.845 36.023 50.674 1.00 15.74 ? 481 ILE A CG2 1 ATOM 3720 C CD1 . ILE A 1 485 ? -7.043 35.853 50.204 1.00 14.52 ? 481 ILE A CD1 1 ATOM 3721 N N . VAL A 1 486 ? -2.165 37.796 53.208 1.00 14.36 ? 482 VAL A N 1 ATOM 3722 C CA . VAL A 1 486 ? -0.881 38.553 53.169 1.00 13.92 ? 482 VAL A CA 1 ATOM 3723 C C . VAL A 1 486 ? 0.196 37.600 52.703 1.00 14.49 ? 482 VAL A C 1 ATOM 3724 O O . VAL A 1 486 ? 0.355 36.526 53.270 1.00 15.21 ? 482 VAL A O 1 ATOM 3725 C CB . VAL A 1 486 ? -0.595 39.209 54.546 1.00 15.70 ? 482 VAL A CB 1 ATOM 3726 C CG1 . VAL A 1 486 ? -0.723 38.212 55.671 1.00 18.17 ? 482 VAL A CG1 1 ATOM 3727 C CG2 . VAL A 1 486 ? 0.792 39.931 54.505 1.00 15.99 ? 482 VAL A CG2 1 ATOM 3728 N N . ALA A 1 487 ? 0.934 37.966 51.663 1.00 13.06 ? 483 ALA A N 1 ATOM 3729 C CA . ALA A 1 487 ? 1.927 37.048 51.089 1.00 13.47 ? 483 ALA A CA 1 ATOM 3730 C C . ALA A 1 487 ? 3.294 37.722 51.177 1.00 12.99 ? 483 ALA A C 1 ATOM 3731 O O . ALA A 1 487 ? 3.481 38.877 50.714 1.00 13.83 ? 483 ALA A O 1 ATOM 3732 C CB . ALA A 1 487 ? 1.597 36.768 49.651 1.00 14.50 ? 483 ALA A CB 1 ATOM 3733 N N . VAL A 1 488 ? 4.223 36.991 51.756 1.00 13.87 ? 484 VAL A N 1 ATOM 3734 C CA . VAL A 1 488 ? 5.604 37.461 52.002 1.00 14.70 ? 484 VAL A CA 1 ATOM 3735 C C . VAL A 1 488 ? 6.589 36.307 51.770 1.00 15.02 ? 484 VAL A C 1 ATOM 3736 O O . VAL A 1 488 ? 6.147 35.153 51.575 1.00 14.33 ? 484 VAL A O 1 ATOM 3737 C CB . VAL A 1 488 ? 5.768 38.061 53.443 1.00 15.41 ? 484 VAL A CB 1 ATOM 3738 C CG1 . VAL A 1 488 ? 4.818 39.270 53.614 1.00 14.67 ? 484 VAL A CG1 1 ATOM 3739 C CG2 . VAL A 1 488 ? 5.560 36.973 54.525 1.00 15.45 ? 484 VAL A CG2 1 ATOM 3740 N N . GLY A 1 489 ? 7.902 36.598 51.833 1.00 14.28 ? 485 GLY A N 1 ATOM 3741 C CA . GLY A 1 489 ? 8.877 35.511 51.773 1.00 14.49 ? 485 GLY A CA 1 ATOM 3742 C C . GLY A 1 489 ? 10.201 35.872 51.141 1.00 14.54 ? 485 GLY A C 1 ATOM 3743 O O . GLY A 1 489 ? 10.610 37.039 51.171 1.00 15.09 ? 485 GLY A O 1 ATOM 3744 N N . GLU A 1 490 ? 10.849 34.843 50.596 1.00 14.36 ? 486 GLU A N 1 ATOM 3745 C CA . GLU A 1 490 ? 12.212 35.040 50.040 1.00 13.47 ? 486 GLU A CA 1 ATOM 3746 C C . GLU A 1 490 ? 12.138 35.723 48.713 1.00 13.95 ? 486 GLU A C 1 ATOM 3747 O O . GLU A 1 490 ? 11.148 35.580 47.951 1.00 14.71 ? 486 GLU A O 1 ATOM 3748 C CB . GLU A 1 490 ? 12.886 33.699 49.851 1.00 14.28 ? 486 GLU A CB 1 ATOM 3749 C CG . GLU A 1 490 ? 13.093 32.978 51.193 1.00 16.62 ? 486 GLU A CG 1 ATOM 3750 C CD . GLU A 1 490 ? 14.038 31.793 51.020 1.00 15.97 ? 486 GLU A CD 1 ATOM 3751 O OE1 . GLU A 1 490 ? 13.771 30.841 50.264 1.00 15.23 ? 486 GLU A OE1 1 ATOM 3752 O OE2 . GLU A 1 490 ? 15.145 31.872 51.619 1.00 18.26 ? 486 GLU A OE2 1 ATOM 3753 N N . HIS A 1 491 ? 13.211 36.420 48.353 1.00 15.66 ? 487 HIS A N 1 ATOM 3754 C CA . HIS A 1 491 ? 13.360 36.914 46.974 1.00 14.82 ? 487 HIS A CA 1 ATOM 3755 C C . HIS A 1 491 ? 14.016 35.841 46.097 1.00 14.27 ? 487 HIS A C 1 ATOM 3756 O O . HIS A 1 491 ? 14.583 34.871 46.620 1.00 15.95 ? 487 HIS A O 1 ATOM 3757 C CB . HIS A 1 491 ? 14.211 38.195 46.976 1.00 16.10 ? 487 HIS A CB 1 ATOM 3758 C CG . HIS A 1 491 ? 13.594 39.335 47.724 1.00 18.57 ? 487 HIS A CG 1 ATOM 3759 N ND1 . HIS A 1 491 ? 14.306 40.478 48.013 1.00 26.25 ? 487 HIS A ND1 1 ATOM 3760 C CD2 . HIS A 1 491 ? 12.367 39.504 48.281 1.00 22.32 ? 487 HIS A CD2 1 ATOM 3761 C CE1 . HIS A 1 491 ? 13.530 41.315 48.685 1.00 26.30 ? 487 HIS A CE1 1 ATOM 3762 N NE2 . HIS A 1 491 ? 12.353 40.747 48.881 1.00 23.88 ? 487 HIS A NE2 1 ATOM 3763 N N . PRO A 1 492 ? 13.889 35.981 44.767 1.00 15.04 ? 488 PRO A N 1 ATOM 3764 C CA . PRO A 1 492 ? 14.445 34.920 43.893 1.00 14.75 ? 488 PRO A CA 1 ATOM 3765 C C . PRO A 1 492 ? 15.967 34.802 44.019 1.00 15.42 ? 488 PRO A C 1 ATOM 3766 O O . PRO A 1 492 ? 16.682 35.812 44.176 1.00 16.12 ? 488 PRO A O 1 ATOM 3767 C CB . PRO A 1 492 ? 14.055 35.385 42.476 1.00 15.06 ? 488 PRO A CB 1 ATOM 3768 C CG . PRO A 1 492 ? 12.793 36.200 42.680 1.00 15.12 ? 488 PRO A CG 1 ATOM 3769 C CD . PRO A 1 492 ? 13.028 36.923 44.040 1.00 14.19 ? 488 PRO A CD 1 ATOM 3770 N N . TYR A 1 493 ? 16.442 33.574 43.947 1.00 14.79 ? 489 TYR A N 1 ATOM 3771 C CA . TYR A 1 493 ? 17.915 33.326 43.952 1.00 14.16 ? 489 TYR A CA 1 ATOM 3772 C C . TYR A 1 493 ? 18.184 31.991 43.331 1.00 14.81 ? 489 TYR A C 1 ATOM 3773 O O . TYR A 1 493 ? 17.301 31.143 43.204 1.00 14.58 ? 489 TYR A O 1 ATOM 3774 C CB . TYR A 1 493 ? 18.471 33.313 45.428 1.00 15.03 ? 489 TYR A CB 1 ATOM 3775 C CG . TYR A 1 493 ? 17.709 32.341 46.341 1.00 14.42 ? 489 TYR A CG 1 ATOM 3776 C CD1 . TYR A 1 493 ? 17.952 30.968 46.289 1.00 15.42 ? 489 TYR A CD1 1 ATOM 3777 C CD2 . TYR A 1 493 ? 16.720 32.813 47.230 1.00 14.22 ? 489 TYR A CD2 1 ATOM 3778 C CE1 . TYR A 1 493 ? 17.277 30.032 47.122 1.00 15.14 ? 489 TYR A CE1 1 ATOM 3779 C CE2 . TYR A 1 493 ? 16.004 31.931 48.028 1.00 15.28 ? 489 TYR A CE2 1 ATOM 3780 C CZ . TYR A 1 493 ? 16.257 30.537 47.966 1.00 13.67 ? 489 TYR A CZ 1 ATOM 3781 O OH . TYR A 1 493 ? 15.593 29.623 48.735 1.00 15.23 ? 489 TYR A OH 1 ATOM 3782 N N . THR A 1 494 ? 19.449 31.795 42.958 1.00 13.95 ? 490 THR A N 1 ATOM 3783 C CA . THR A 1 494 ? 19.912 30.608 42.306 1.00 15.07 ? 490 THR A CA 1 ATOM 3784 C C . THR A 1 494 ? 21.367 30.350 42.754 1.00 13.98 ? 490 THR A C 1 ATOM 3785 O O . THR A 1 494 ? 22.148 31.285 42.874 1.00 15.94 ? 490 THR A O 1 ATOM 3786 C CB . THR A 1 494 ? 19.878 30.837 40.775 1.00 16.00 ? 490 THR A CB 1 ATOM 3787 O OG1 . THR A 1 494 ? 18.496 31.114 40.459 1.00 16.77 ? 490 THR A OG1 1 ATOM 3788 C CG2 . THR A 1 494 ? 20.292 29.589 40.038 1.00 17.48 ? 490 THR A CG2 1 ATOM 3789 N N . GLU A 1 495 ? 21.648 29.094 43.000 1.00 15.12 ? 491 GLU A N 1 ATOM 3790 C CA . GLU A 1 495 ? 23.064 28.677 43.263 1.00 14.89 ? 491 GLU A CA 1 ATOM 3791 C C . GLU A 1 495 ? 23.664 29.470 44.425 1.00 16.15 ? 491 GLU A C 1 ATOM 3792 O O . GLU A 1 495 ? 23.006 29.604 45.468 1.00 16.77 ? 491 GLU A O 1 ATOM 3793 C CB . GLU A 1 495 ? 23.888 28.725 41.947 1.00 15.23 ? 491 GLU A CB 1 ATOM 3794 C CG . GLU A 1 495 ? 23.405 27.608 40.936 1.00 15.81 ? 491 GLU A CG 1 ATOM 3795 C CD . GLU A 1 495 ? 24.137 27.712 39.624 1.00 21.11 ? 491 GLU A CD 1 ATOM 3796 O OE1 . GLU A 1 495 ? 25.381 27.750 39.632 1.00 19.94 ? 491 GLU A OE1 1 ATOM 3797 O OE2 . GLU A 1 495 ? 23.509 27.776 38.558 1.00 18.01 ? 491 GLU A OE2 1 ATOM 3798 N N . THR A 1 496 ? 24.896 29.967 44.296 1.00 16.99 ? 492 THR A N 1 ATOM 3799 C CA . THR A 1 496 ? 25.590 30.457 45.505 1.00 18.05 ? 492 THR A CA 1 ATOM 3800 C C . THR A 1 496 ? 24.924 31.686 46.104 1.00 18.97 ? 492 THR A C 1 ATOM 3801 O O . THR A 1 496 ? 24.946 31.878 47.349 1.00 19.64 ? 492 THR A O 1 ATOM 3802 C CB . THR A 1 496 ? 27.065 30.730 45.172 1.00 17.54 ? 492 THR A CB 1 ATOM 3803 O OG1 . THR A 1 496 ? 27.661 29.505 44.781 1.00 19.66 ? 492 THR A OG1 1 ATOM 3804 C CG2 . THR A 1 496 ? 27.786 31.250 46.458 1.00 20.73 ? 492 THR A CG2 1 ATOM 3805 N N . LYS A 1 497 ? 24.276 32.509 45.269 1.00 18.52 ? 493 LYS A N 1 ATOM 3806 C CA . LYS A 1 497 ? 23.536 33.670 45.773 1.00 19.13 ? 493 LYS A CA 1 ATOM 3807 C C . LYS A 1 497 ? 22.482 33.273 46.781 1.00 19.06 ? 493 LYS A C 1 ATOM 3808 O O . LYS A 1 497 ? 22.139 34.088 47.664 1.00 21.18 ? 493 LYS A O 1 ATOM 3809 C CB . LYS A 1 497 ? 22.888 34.453 44.651 1.00 20.28 ? 493 LYS A CB 1 ATOM 3810 C CG . LYS A 1 497 ? 23.917 35.232 43.822 1.00 24.57 ? 493 LYS A CG 1 ATOM 3811 C CD . LYS A 1 497 ? 24.231 36.559 44.559 1.00 30.75 ? 493 LYS A CD 1 ATOM 3812 C CE . LYS A 1 497 ? 25.053 37.534 43.730 1.00 34.59 ? 493 LYS A CE 1 ATOM 3813 N NZ . LYS A 1 497 ? 25.413 38.722 44.620 1.00 35.54 ? 493 LYS A NZ 1 ATOM 3814 N N . GLY A 1 498 ? 21.957 32.067 46.651 1.00 17.69 ? 494 GLY A N 1 ATOM 3815 C CA . GLY A 1 498 ? 20.942 31.565 47.586 1.00 18.11 ? 494 GLY A CA 1 ATOM 3816 C C . GLY A 1 498 ? 21.486 30.961 48.871 1.00 18.28 ? 494 GLY A C 1 ATOM 3817 O O . GLY A 1 498 ? 20.719 30.665 49.780 1.00 17.80 ? 494 GLY A O 1 ATOM 3818 N N . ASP A 1 499 ? 22.799 30.703 48.945 1.00 18.05 ? 495 ASP A N 1 ATOM 3819 C CA . ASP A 1 499 ? 23.337 30.137 50.219 1.00 17.83 ? 495 ASP A CA 1 ATOM 3820 C C . ASP A 1 499 ? 23.091 31.193 51.307 1.00 16.44 ? 495 ASP A C 1 ATOM 3821 O O . ASP A 1 499 ? 23.302 32.415 51.104 1.00 19.83 ? 495 ASP A O 1 ATOM 3822 C CB . ASP A 1 499 ? 24.856 29.914 50.123 1.00 17.67 ? 495 ASP A CB 1 ATOM 3823 C CG . ASP A 1 499 ? 25.231 28.758 49.211 1.00 19.78 ? 495 ASP A CG 1 ATOM 3824 O OD1 . ASP A 1 499 ? 24.390 27.977 48.703 1.00 19.98 ? 495 ASP A OD1 1 ATOM 3825 O OD2 . ASP A 1 499 ? 26.470 28.583 49.051 1.00 21.31 ? 495 ASP A OD2 1 ATOM 3826 N N . ASN A 1 500 ? 22.615 30.715 52.452 1.00 18.51 ? 496 ASN A N 1 ATOM 3827 C CA . ASN A 1 500 ? 22.077 31.630 53.439 1.00 19.20 ? 496 ASN A CA 1 ATOM 3828 C C . ASN A 1 500 ? 22.170 30.967 54.821 1.00 19.03 ? 496 ASN A C 1 ATOM 3829 O O . ASN A 1 500 ? 21.554 29.943 55.092 1.00 19.15 ? 496 ASN A O 1 ATOM 3830 C CB . ASN A 1 500 ? 20.629 31.996 53.049 1.00 19.86 ? 496 ASN A CB 1 ATOM 3831 C CG . ASN A 1 500 ? 20.040 33.069 53.927 1.00 24.40 ? 496 ASN A CG 1 ATOM 3832 O OD1 . ASN A 1 500 ? 20.395 33.202 55.116 1.00 23.32 ? 496 ASN A OD1 1 ATOM 3833 N ND2 . ASN A 1 500 ? 19.107 33.846 53.365 1.00 24.60 ? 496 ASN A ND2 1 ATOM 3834 N N . LEU A 1 501 ? 23.017 31.568 55.690 1.00 21.96 ? 497 LEU A N 1 ATOM 3835 C CA . LEU A 1 501 ? 23.264 31.011 57.016 1.00 23.74 ? 497 LEU A CA 1 ATOM 3836 C C . LEU A 1 501 ? 22.208 31.407 58.044 1.00 24.90 ? 497 LEU A C 1 ATOM 3837 O O . LEU A 1 501 ? 22.082 30.717 59.075 1.00 25.54 ? 497 LEU A O 1 ATOM 3838 C CB . LEU A 1 501 ? 24.666 31.442 57.504 1.00 23.61 ? 497 LEU A CB 1 ATOM 3839 C CG . LEU A 1 501 ? 25.806 30.827 56.665 1.00 24.02 ? 497 LEU A CG 1 ATOM 3840 C CD1 . LEU A 1 501 ? 27.167 31.288 57.219 1.00 28.48 ? 497 LEU A CD1 1 ATOM 3841 C CD2 . LEU A 1 501 ? 25.754 29.323 56.637 1.00 24.48 ? 497 LEU A CD2 1 ATOM 3842 N N . ASN A 1 502 ? 21.431 32.453 57.743 1.00 23.57 ? 498 ASN A N 1 ATOM 3843 C CA . ASN A 1 502 ? 20.430 32.954 58.722 1.00 24.24 ? 498 ASN A CA 1 ATOM 3844 C C . ASN A 1 502 ? 18.970 32.514 58.486 1.00 23.09 ? 498 ASN A C 1 ATOM 3845 O O . ASN A 1 502 ? 18.161 32.404 59.429 1.00 22.32 ? 498 ASN A O 1 ATOM 3846 C CB . ASN A 1 502 ? 20.517 34.466 58.878 1.00 25.54 ? 498 ASN A CB 1 ATOM 3847 C CG . ASN A 1 502 ? 20.168 35.219 57.608 1.00 34.86 ? 498 ASN A CG 1 ATOM 3848 O OD1 . ASN A 1 502 ? 18.977 35.315 57.232 1.00 38.99 ? 498 ASN A OD1 1 ATOM 3849 N ND2 . ASN A 1 502 ? 21.192 35.770 56.932 1.00 43.79 ? 498 ASN A ND2 1 ATOM 3850 N N . LEU A 1 503 ? 18.632 32.286 57.207 1.00 20.12 ? 499 LEU A N 1 ATOM 3851 C CA . LEU A 1 503 ? 17.293 31.813 56.801 1.00 19.57 ? 499 LEU A CA 1 ATOM 3852 C C . LEU A 1 503 ? 16.158 32.649 57.408 1.00 19.48 ? 499 LEU A C 1 ATOM 3853 O O . LEU A 1 503 ? 15.096 32.072 57.769 1.00 19.91 ? 499 LEU A O 1 ATOM 3854 C CB . LEU A 1 503 ? 17.135 30.296 57.039 1.00 18.70 ? 499 LEU A CB 1 ATOM 3855 C CG . LEU A 1 503 ? 18.124 29.375 56.285 1.00 17.66 ? 499 LEU A CG 1 ATOM 3856 C CD1 . LEU A 1 503 ? 17.841 27.930 56.550 1.00 20.01 ? 499 LEU A CD1 1 ATOM 3857 C CD2 . LEU A 1 503 ? 18.074 29.688 54.749 1.00 20.96 ? 499 LEU A CD2 1 ATOM 3858 N N . THR A 1 504 ? 16.359 33.970 57.457 1.00 20.80 ? 500 THR A N 1 ATOM 3859 C CA . THR A 1 504 ? 15.289 34.879 57.878 1.00 22.06 ? 500 THR A CA 1 ATOM 3860 C C . THR A 1 504 ? 14.810 35.665 56.649 1.00 22.17 ? 500 THR A C 1 ATOM 3861 O O . THR A 1 504 ? 15.622 36.199 55.845 1.00 23.38 ? 500 THR A O 1 ATOM 3862 C CB . THR A 1 504 ? 15.736 35.854 58.962 1.00 24.06 ? 500 THR A CB 1 ATOM 3863 O OG1 . THR A 1 504 ? 16.717 36.721 58.399 1.00 30.56 ? 500 THR A OG1 1 ATOM 3864 C CG2 . THR A 1 504 ? 16.356 35.098 60.126 1.00 24.18 ? 500 THR A CG2 1 ATOM 3865 N N . ILE A 1 505 ? 13.494 35.753 56.490 1.00 21.86 ? 501 ILE A N 1 ATOM 3866 C CA . ILE A 1 505 ? 12.983 36.472 55.345 1.00 22.03 ? 501 ILE A CA 1 ATOM 3867 C C . ILE A 1 505 ? 13.286 37.964 55.372 1.00 23.56 ? 501 ILE A C 1 ATOM 3868 O O . ILE A 1 505 ? 13.419 38.559 56.451 1.00 23.05 ? 501 ILE A O 1 ATOM 3869 C CB . ILE A 1 505 ? 11.482 36.192 55.099 1.00 21.40 ? 501 ILE A CB 1 ATOM 3870 C CG1 . ILE A 1 505 ? 10.613 36.816 56.197 1.00 19.72 ? 501 ILE A CG1 1 ATOM 3871 C CG2 . ILE A 1 505 ? 11.229 34.696 54.950 1.00 21.00 ? 501 ILE A CG2 1 ATOM 3872 C CD1 . ILE A 1 505 ? 9.115 36.872 55.759 1.00 22.50 ? 501 ILE A CD1 1 ATOM 3873 N N . PRO A 1 506 ? 13.410 38.570 54.190 1.00 24.68 ? 502 PRO A N 1 ATOM 3874 C CA . PRO A 1 506 ? 13.720 39.996 54.083 1.00 25.65 ? 502 PRO A CA 1 ATOM 3875 C C . PRO A 1 506 ? 12.602 40.816 54.659 1.00 26.89 ? 502 PRO A C 1 ATOM 3876 O O . PRO A 1 506 ? 11.447 40.447 54.589 1.00 25.83 ? 502 PRO A O 1 ATOM 3877 C CB . PRO A 1 506 ? 13.823 40.249 52.566 1.00 26.00 ? 502 PRO A CB 1 ATOM 3878 C CG . PRO A 1 506 ? 13.654 38.981 51.909 1.00 27.04 ? 502 PRO A CG 1 ATOM 3879 C CD . PRO A 1 506 ? 13.480 37.870 52.889 1.00 24.99 ? 502 PRO A CD 1 ATOM 3880 N N . GLU A 1 507 ? 12.960 41.923 55.272 1.00 28.30 ? 503 GLU A N 1 ATOM 3881 C CA . GLU A 1 507 ? 11.955 42.890 55.647 1.00 29.45 ? 503 GLU A CA 1 ATOM 3882 C C . GLU A 1 507 ? 11.621 43.762 54.475 1.00 30.04 ? 503 GLU A C 1 ATOM 3883 O O . GLU A 1 507 ? 12.463 43.929 53.576 1.00 31.40 ? 503 GLU A O 1 ATOM 3884 C CB . GLU A 1 507 ? 12.362 43.600 56.927 1.00 31.68 ? 503 GLU A CB 1 ATOM 3885 C CG . GLU A 1 507 ? 12.213 42.576 58.091 1.00 31.79 ? 503 GLU A CG 1 ATOM 3886 C CD . GLU A 1 507 ? 10.791 41.922 58.120 1.00 35.18 ? 503 GLU A CD 1 ATOM 3887 O OE1 . GLU A 1 507 ? 9.882 42.749 58.489 1.00 25.47 ? 503 GLU A OE1 1 ATOM 3888 O OE2 . GLU A 1 507 ? 10.612 40.644 57.786 1.00 29.60 ? 503 GLU A OE2 1 ATOM 3889 N N . PRO A 1 508 ? 10.384 44.297 54.430 1.00 29.10 ? 504 PRO A N 1 ATOM 3890 C CA . PRO A 1 508 ? 9.363 44.359 55.507 1.00 28.23 ? 504 PRO A CA 1 ATOM 3891 C C . PRO A 1 508 ? 8.368 43.183 55.773 1.00 26.94 ? 504 PRO A C 1 ATOM 3892 O O . PRO A 1 508 ? 7.279 43.418 56.332 1.00 28.90 ? 504 PRO A O 1 ATOM 3893 C CB . PRO A 1 508 ? 8.548 45.596 55.114 1.00 28.28 ? 504 PRO A CB 1 ATOM 3894 C CG . PRO A 1 508 ? 8.592 45.603 53.618 1.00 28.58 ? 504 PRO A CG 1 ATOM 3895 C CD . PRO A 1 508 ? 10.014 45.138 53.275 1.00 31.12 ? 504 PRO A CD 1 ATOM 3896 N N . GLY A 1 509 ? 8.700 41.965 55.417 1.00 24.00 ? 505 GLY A N 1 ATOM 3897 C CA . GLY A 1 509 ? 7.713 40.847 55.466 1.00 20.26 ? 505 GLY A CA 1 ATOM 3898 C C . GLY A 1 509 ? 7.031 40.575 56.785 1.00 19.82 ? 505 GLY A C 1 ATOM 3899 O O . GLY A 1 509 ? 5.781 40.662 56.877 1.00 18.55 ? 505 GLY A O 1 ATOM 3900 N N . LEU A 1 510 ? 7.824 40.231 57.812 1.00 19.70 ? 506 LEU A N 1 ATOM 3901 C CA . LEU A 1 510 ? 7.238 39.994 59.127 1.00 19.28 ? 506 LEU A CA 1 ATOM 3902 C C . LEU A 1 510 ? 6.531 41.260 59.619 1.00 18.84 ? 506 LEU A C 1 ATOM 3903 O O . LEU A 1 510 ? 5.425 41.158 60.182 1.00 18.46 ? 506 LEU A O 1 ATOM 3904 C CB . LEU A 1 510 ? 8.343 39.596 60.135 1.00 17.93 ? 506 LEU A CB 1 ATOM 3905 C CG . LEU A 1 510 ? 7.840 39.487 61.561 1.00 18.36 ? 506 LEU A CG 1 ATOM 3906 C CD1 . LEU A 1 510 ? 6.862 38.321 61.771 1.00 19.45 ? 506 LEU A CD1 1 ATOM 3907 C CD2 . LEU A 1 510 ? 9.105 39.312 62.373 1.00 21.65 ? 506 LEU A CD2 1 ATOM 3908 N N . SER A 1 511 ? 7.118 42.454 59.460 1.00 19.50 ? 507 SER A N 1 ATOM 3909 C CA . SER A 1 511 ? 6.406 43.682 59.922 1.00 19.71 ? 507 SER A CA 1 ATOM 3910 C C . SER A 1 511 ? 5.022 43.839 59.247 1.00 19.20 ? 507 SER A C 1 ATOM 3911 O O . SER A 1 511 ? 4.041 44.245 59.921 1.00 18.85 ? 507 SER A O 1 ATOM 3912 C CB . SER A 1 511 ? 7.251 44.964 59.780 1.00 21.92 ? 507 SER A CB 1 ATOM 3913 O OG . SER A 1 511 ? 7.550 45.187 58.418 1.00 26.05 ? 507 SER A OG 1 ATOM 3914 N N . THR A 1 512 ? 4.940 43.487 57.959 1.00 17.80 ? 508 THR A N 1 ATOM 3915 C CA . THR A 1 512 ? 3.664 43.615 57.232 1.00 17.93 ? 508 THR A CA 1 ATOM 3916 C C . THR A 1 512 ? 2.680 42.584 57.762 1.00 16.57 ? 508 THR A C 1 ATOM 3917 O O . THR A 1 512 ? 1.514 42.914 58.031 1.00 16.88 ? 508 THR A O 1 ATOM 3918 C CB . THR A 1 512 ? 3.878 43.538 55.710 1.00 19.16 ? 508 THR A CB 1 ATOM 3919 O OG1 . THR A 1 512 ? 4.585 44.725 55.326 1.00 24.24 ? 508 THR A OG1 1 ATOM 3920 C CG2 . THR A 1 512 ? 2.532 43.561 54.928 1.00 17.73 ? 508 THR A CG2 1 ATOM 3921 N N . VAL A 1 513 ? 3.122 41.357 57.963 1.00 16.88 ? 509 VAL A N 1 ATOM 3922 C CA . VAL A 1 513 ? 2.249 40.346 58.554 1.00 16.27 ? 509 VAL A CA 1 ATOM 3923 C C . VAL A 1 513 ? 1.742 40.797 59.950 1.00 16.73 ? 509 VAL A C 1 ATOM 3924 O O . VAL A 1 513 ? 0.542 40.658 60.258 1.00 16.96 ? 509 VAL A O 1 ATOM 3925 C CB . VAL A 1 513 ? 2.958 38.977 58.607 1.00 16.38 ? 509 VAL A CB 1 ATOM 3926 C CG1 . VAL A 1 513 ? 2.142 37.987 59.472 1.00 17.04 ? 509 VAL A CG1 1 ATOM 3927 C CG2 . VAL A 1 513 ? 3.207 38.440 57.169 1.00 15.84 ? 509 VAL A CG2 1 ATOM 3928 N N . GLN A 1 514 ? 2.642 41.312 60.790 1.00 16.96 ? 510 GLN A N 1 ATOM 3929 C CA . GLN A 1 514 ? 2.204 41.784 62.101 1.00 17.92 ? 510 GLN A CA 1 ATOM 3930 C C . GLN A 1 514 ? 1.192 42.950 61.989 1.00 18.39 ? 510 GLN A C 1 ATOM 3931 O O . GLN A 1 514 ? 0.171 42.962 62.736 1.00 19.17 ? 510 GLN A O 1 ATOM 3932 C CB . GLN A 1 514 ? 3.452 42.172 62.909 1.00 19.05 ? 510 GLN A CB 1 ATOM 3933 C CG . GLN A 1 514 ? 4.278 40.965 63.258 1.00 18.03 ? 510 GLN A CG 1 ATOM 3934 C CD . GLN A 1 514 ? 5.638 41.325 63.891 1.00 19.91 ? 510 GLN A CD 1 ATOM 3935 O OE1 . GLN A 1 514 ? 6.190 42.415 63.613 1.00 24.20 ? 510 GLN A OE1 1 ATOM 3936 N NE2 . GLN A 1 514 ? 6.177 40.424 64.697 1.00 22.77 ? 510 GLN A NE2 1 ATOM 3937 N N . ALA A 1 515 ? 1.420 43.909 61.093 1.00 18.06 ? 511 ALA A N 1 ATOM 3938 C CA . ALA A 1 515 ? 0.477 45.013 60.928 1.00 19.39 ? 511 ALA A CA 1 ATOM 3939 C C . ALA A 1 515 ? -0.909 44.545 60.466 1.00 20.11 ? 511 ALA A C 1 ATOM 3940 O O . ALA A 1 515 ? -1.949 44.958 61.013 1.00 20.90 ? 511 ALA A O 1 ATOM 3941 C CB . ALA A 1 515 ? 1.065 46.075 59.971 1.00 19.96 ? 511 ALA A CB 1 ATOM 3942 N N . VAL A 1 516 ? -0.926 43.635 59.489 1.00 18.75 ? 512 VAL A N 1 ATOM 3943 C CA . VAL A 1 516 ? -2.167 43.163 58.884 1.00 18.17 ? 512 VAL A CA 1 ATOM 3944 C C . VAL A 1 516 ? -2.930 42.293 59.877 1.00 18.98 ? 512 VAL A C 1 ATOM 3945 O O . VAL A 1 516 ? -4.145 42.529 60.114 1.00 18.35 ? 512 VAL A O 1 ATOM 3946 C CB . VAL A 1 516 ? -1.857 42.386 57.562 1.00 17.65 ? 512 VAL A CB 1 ATOM 3947 C CG1 . VAL A 1 516 ? -3.114 41.623 57.056 1.00 19.26 ? 512 VAL A CG1 1 ATOM 3948 C CG2 . VAL A 1 516 ? -1.360 43.342 56.503 1.00 19.33 ? 512 VAL A CG2 1 ATOM 3949 N N . CYS A 1 517 ? -2.264 41.269 60.410 1.00 19.27 ? 513 CYS A N 1 ATOM 3950 C CA . CYS A 1 517 ? -2.888 40.311 61.301 1.00 19.98 ? 513 CYS A CA 1 ATOM 3951 C C . CYS A 1 517 ? -3.293 40.983 62.622 1.00 20.68 ? 513 CYS A C 1 ATOM 3952 O O . CYS A 1 517 ? -4.231 40.532 63.289 1.00 21.56 ? 513 CYS A O 1 ATOM 3953 C CB . CYS A 1 517 ? -1.947 39.144 61.579 1.00 19.47 ? 513 CYS A CB 1 ATOM 3954 S SG . CYS A 1 517 ? -1.497 38.214 60.005 1.00 22.79 ? 513 CYS A SG 1 ATOM 3955 N N . GLY A 1 518 ? -2.589 42.038 62.995 1.00 20.80 ? 514 GLY A N 1 ATOM 3956 C CA . GLY A 1 518 ? -3.000 42.734 64.227 1.00 21.36 ? 514 GLY A CA 1 ATOM 3957 C C . GLY A 1 518 ? -4.329 43.450 64.047 1.00 22.34 ? 514 GLY A C 1 ATOM 3958 O O . GLY A 1 518 ? -4.989 43.757 65.066 1.00 23.71 ? 514 GLY A O 1 ATOM 3959 N N . GLY A 1 519 ? -4.721 43.734 62.804 1.00 21.50 ? 515 GLY A N 1 ATOM 3960 C CA . GLY A 1 519 ? -5.918 44.522 62.527 1.00 21.98 ? 515 GLY A CA 1 ATOM 3961 C C . GLY A 1 519 ? -7.124 43.747 62.053 1.00 22.21 ? 515 GLY A C 1 ATOM 3962 O O . GLY A 1 519 ? -8.251 44.251 62.167 1.00 22.17 ? 515 GLY A O 1 ATOM 3963 N N . VAL A 1 520 ? -6.917 42.542 61.481 1.00 18.50 ? 516 VAL A N 1 ATOM 3964 C CA . VAL A 1 520 ? -8.058 41.752 60.977 1.00 18.75 ? 516 VAL A CA 1 ATOM 3965 C C . VAL A 1 520 ? -7.560 40.316 60.877 1.00 18.52 ? 516 VAL A C 1 ATOM 3966 O O . VAL A 1 520 ? -6.349 40.088 60.789 1.00 18.28 ? 516 VAL A O 1 ATOM 3967 C CB . VAL A 1 520 ? -8.485 42.269 59.603 1.00 17.46 ? 516 VAL A CB 1 ATOM 3968 C CG1 . VAL A 1 520 ? -7.406 41.984 58.497 1.00 19.19 ? 516 VAL A CG1 1 ATOM 3969 C CG2 . VAL A 1 520 ? -9.852 41.724 59.157 1.00 20.00 ? 516 VAL A CG2 1 ATOM 3970 N N . ARG A 1 521 ? -8.465 39.350 60.881 1.00 18.28 ? 517 ARG A N 1 ATOM 3971 C CA . ARG A 1 521 ? -8.046 37.965 60.779 1.00 18.37 ? 517 ARG A CA 1 ATOM 3972 C C . ARG A 1 521 ? -7.331 37.764 59.450 1.00 17.19 ? 517 ARG A C 1 ATOM 3973 O O . ARG A 1 521 ? -7.762 38.322 58.454 1.00 16.93 ? 517 ARG A O 1 ATOM 3974 C CB . ARG A 1 521 ? -9.235 37.055 60.756 1.00 18.87 ? 517 ARG A CB 1 ATOM 3975 C CG . ARG A 1 521 ? -9.879 36.906 62.022 1.00 29.60 ? 517 ARG A CG 1 ATOM 3976 C CD . ARG A 1 521 ? -10.831 35.728 61.948 1.00 37.02 ? 517 ARG A CD 1 ATOM 3977 N NE . ARG A 1 521 ? -10.181 34.449 62.321 1.00 40.47 ? 517 ARG A NE 1 ATOM 3978 C CZ . ARG A 1 521 ? -10.763 33.241 62.167 1.00 38.90 ? 517 ARG A CZ 1 ATOM 3979 N NH1 . ARG A 1 521 ? -12.030 33.224 61.614 1.00 24.02 ? 517 ARG A NH1 1 ATOM 3980 N NH2 . ARG A 1 521 ? -10.056 32.100 62.546 1.00 25.73 ? 517 ARG A NH2 1 ATOM 3981 N N . CYS A 1 522 ? -6.306 36.934 59.468 1.00 16.96 ? 518 CYS A N 1 ATOM 3982 C CA . CYS A 1 522 ? -5.386 36.897 58.265 1.00 17.58 ? 518 CYS A CA 1 ATOM 3983 C C . CYS A 1 522 ? -4.959 35.488 57.935 1.00 17.28 ? 518 CYS A C 1 ATOM 3984 O O . CYS A 1 522 ? -4.666 34.687 58.837 1.00 17.54 ? 518 CYS A O 1 ATOM 3985 C CB . CYS A 1 522 ? -4.113 37.722 58.516 1.00 18.86 ? 518 CYS A CB 1 ATOM 3986 S SG . CYS A 1 522 ? -3.059 36.955 59.781 1.00 24.64 ? 518 CYS A SG 1 ATOM 3987 N N . ALA A 1 523 ? -4.820 35.235 56.638 1.00 16.86 ? 519 ALA A N 1 ATOM 3988 C CA . ALA A 1 523 ? -4.133 34.040 56.146 1.00 16.14 ? 519 ALA A CA 1 ATOM 3989 C C . ALA A 1 523 ? -2.784 34.517 55.577 1.00 15.37 ? 519 ALA A C 1 ATOM 3990 O O . ALA A 1 523 ? -2.788 35.344 54.651 1.00 15.45 ? 519 ALA A O 1 ATOM 3991 C CB . ALA A 1 523 ? -4.962 33.402 55.051 1.00 15.22 ? 519 ALA A CB 1 ATOM 3992 N N . THR A 1 524 ? -1.686 34.013 56.129 1.00 14.25 ? 520 THR A N 1 ATOM 3993 C CA . THR A 1 524 ? -0.343 34.352 55.639 1.00 14.78 ? 520 THR A CA 1 ATOM 3994 C C . THR A 1 524 ? 0.096 33.285 54.620 1.00 14.88 ? 520 THR A C 1 ATOM 3995 O O . THR A 1 524 ? 0.091 32.071 54.910 1.00 15.05 ? 520 THR A O 1 ATOM 3996 C CB . THR A 1 524 ? 0.596 34.429 56.791 1.00 14.78 ? 520 THR A CB 1 ATOM 3997 O OG1 . THR A 1 524 ? 0.184 35.543 57.621 1.00 15.94 ? 520 THR A OG1 1 ATOM 3998 C CG2 . THR A 1 524 ? 2.063 34.612 56.330 1.00 16.77 ? 520 THR A CG2 1 ATOM 3999 N N . VAL A 1 525 ? 0.503 33.731 53.432 1.00 14.11 ? 521 VAL A N 1 ATOM 4000 C CA . VAL A 1 525 ? 1.053 32.813 52.422 1.00 13.71 ? 521 VAL A CA 1 ATOM 4001 C C . VAL A 1 525 ? 2.549 33.096 52.345 1.00 13.02 ? 521 VAL A C 1 ATOM 4002 O O . VAL A 1 525 ? 2.941 34.192 51.996 1.00 15.11 ? 521 VAL A O 1 ATOM 4003 C CB . VAL A 1 525 ? 0.406 33.050 51.065 1.00 12.87 ? 521 VAL A CB 1 ATOM 4004 C CG1 . VAL A 1 525 ? 1.022 32.127 49.996 1.00 15.33 ? 521 VAL A CG1 1 ATOM 4005 C CG2 . VAL A 1 525 ? -1.162 32.886 51.150 1.00 13.62 ? 521 VAL A CG2 1 ATOM 4006 N N . LEU A 1 526 ? 3.353 32.108 52.758 1.00 12.86 ? 522 LEU A N 1 ATOM 4007 C CA . LEU A 1 526 ? 4.798 32.213 52.779 1.00 13.82 ? 522 LEU A CA 1 ATOM 4008 C C . LEU A 1 526 ? 5.381 31.598 51.499 1.00 12.84 ? 522 LEU A C 1 ATOM 4009 O O . LEU A 1 526 ? 5.191 30.426 51.201 1.00 14.38 ? 522 LEU A O 1 ATOM 4010 C CB . LEU A 1 526 ? 5.314 31.474 54.016 1.00 13.68 ? 522 LEU A CB 1 ATOM 4011 C CG . LEU A 1 526 ? 6.845 31.345 54.125 1.00 15.46 ? 522 LEU A CG 1 ATOM 4012 C CD1 . LEU A 1 526 ? 7.486 32.734 54.250 1.00 16.44 ? 522 LEU A CD1 1 ATOM 4013 C CD2 . LEU A 1 526 ? 7.192 30.479 55.329 1.00 18.65 ? 522 LEU A CD2 1 ATOM 4014 N N . ILE A 1 527 ? 6.058 32.459 50.736 1.00 13.01 ? 523 ILE A N 1 ATOM 4015 C CA . ILE A 1 527 ? 6.727 32.063 49.469 1.00 14.28 ? 523 ILE A CA 1 ATOM 4016 C C . ILE A 1 527 ? 8.199 31.902 49.789 1.00 14.01 ? 523 ILE A C 1 ATOM 4017 O O . ILE A 1 527 ? 8.849 32.826 50.272 1.00 15.55 ? 523 ILE A O 1 ATOM 4018 C CB . ILE A 1 527 ? 6.526 33.211 48.433 1.00 14.68 ? 523 ILE A CB 1 ATOM 4019 C CG1 . ILE A 1 527 ? 5.020 33.391 48.115 1.00 16.55 ? 523 ILE A CG1 1 ATOM 4020 C CG2 . ILE A 1 527 ? 7.384 32.941 47.153 1.00 14.27 ? 523 ILE A CG2 1 ATOM 4021 C CD1 . ILE A 1 527 ? 4.356 32.260 47.336 1.00 16.82 ? 523 ILE A CD1 1 ATOM 4022 N N . SER A 1 528 ? 8.687 30.674 49.639 1.00 12.55 ? 524 SER A N 1 ATOM 4023 C CA . SER A 1 528 ? 10.135 30.412 49.947 1.00 14.23 ? 524 SER A CA 1 ATOM 4024 C C . SER A 1 528 ? 10.607 29.186 49.191 1.00 14.99 ? 524 SER A C 1 ATOM 4025 O O . SER A 1 528 ? 9.817 28.392 48.726 1.00 14.98 ? 524 SER A O 1 ATOM 4026 C CB . SER A 1 528 ? 10.346 30.234 51.484 1.00 14.57 ? 524 SER A CB 1 ATOM 4027 O OG . SER A 1 528 ? 9.712 29.018 51.869 1.00 16.42 ? 524 SER A OG 1 ATOM 4028 N N . GLY A 1 529 ? 11.935 29.026 49.127 1.00 15.22 ? 525 GLY A N 1 ATOM 4029 C CA . GLY A 1 529 ? 12.503 27.839 48.463 1.00 15.78 ? 525 GLY A CA 1 ATOM 4030 C C . GLY A 1 529 ? 12.787 26.711 49.440 1.00 15.94 ? 525 GLY A C 1 ATOM 4031 O O . GLY A 1 529 ? 13.354 25.709 49.057 1.00 16.21 ? 525 GLY A O 1 ATOM 4032 N N . ARG A 1 530 ? 12.373 26.858 50.708 1.00 15.89 ? 526 ARG A N 1 ATOM 4033 C CA . ARG A 1 530 ? 12.925 26.057 51.806 1.00 16.37 ? 526 ARG A CA 1 ATOM 4034 C C . ARG A 1 530 ? 12.235 26.526 53.106 1.00 16.63 ? 526 ARG A C 1 ATOM 4035 O O . ARG A 1 530 ? 11.703 27.617 53.191 1.00 16.87 ? 526 ARG A O 1 ATOM 4036 C CB . ARG A 1 530 ? 14.435 26.363 51.965 1.00 15.86 ? 526 ARG A CB 1 ATOM 4037 C CG . ARG A 1 530 ? 14.791 27.833 51.966 1.00 16.30 ? 526 ARG A CG 1 ATOM 4038 C CD . ARG A 1 530 ? 16.292 28.008 52.101 1.00 15.41 ? 526 ARG A CD 1 ATOM 4039 N NE . ARG A 1 530 ? 16.641 29.347 51.760 1.00 16.82 ? 526 ARG A NE 1 ATOM 4040 C CZ . ARG A 1 530 ? 17.839 29.721 51.302 1.00 14.72 ? 526 ARG A CZ 1 ATOM 4041 N NH1 . ARG A 1 530 ? 18.831 28.837 51.242 1.00 17.46 ? 526 ARG A NH1 1 ATOM 4042 N NH2 . ARG A 1 530 ? 18.022 30.956 50.921 1.00 15.61 ? 526 ARG A NH2 1 ATOM 4043 N N . PRO A 1 531 ? 12.367 25.727 54.151 1.00 16.94 ? 527 PRO A N 1 ATOM 4044 C CA . PRO A 1 531 ? 11.989 26.255 55.464 1.00 17.78 ? 527 PRO A CA 1 ATOM 4045 C C . PRO A 1 531 ? 12.826 27.462 55.834 1.00 17.29 ? 527 PRO A C 1 ATOM 4046 O O . PRO A 1 531 ? 14.069 27.568 55.526 1.00 18.11 ? 527 PRO A O 1 ATOM 4047 C CB . PRO A 1 531 ? 12.260 25.053 56.418 1.00 17.60 ? 527 PRO A CB 1 ATOM 4048 C CG . PRO A 1 531 ? 13.106 24.126 55.647 1.00 22.62 ? 527 PRO A CG 1 ATOM 4049 C CD . PRO A 1 531 ? 12.824 24.331 54.182 1.00 18.02 ? 527 PRO A CD 1 ATOM 4050 N N . VAL A 1 532 ? 12.183 28.419 56.484 1.00 16.64 ? 528 VAL A N 1 ATOM 4051 C CA . VAL A 1 532 ? 12.810 29.649 56.964 1.00 17.16 ? 528 VAL A CA 1 ATOM 4052 C C . VAL A 1 532 ? 12.347 29.850 58.399 1.00 17.59 ? 528 VAL A C 1 ATOM 4053 O O . VAL A 1 532 ? 11.356 29.241 58.789 1.00 18.67 ? 528 VAL A O 1 ATOM 4054 C CB . VAL A 1 532 ? 12.473 30.907 56.087 1.00 17.31 ? 528 VAL A CB 1 ATOM 4055 C CG1 . VAL A 1 532 ? 13.146 30.777 54.704 1.00 17.73 ? 528 VAL A CG1 1 ATOM 4056 C CG2 . VAL A 1 532 ? 10.943 31.050 55.912 1.00 16.90 ? 528 VAL A CG2 1 ATOM 4057 N N . VAL A 1 533 ? 13.008 30.745 59.132 1.00 18.72 ? 529 VAL A N 1 ATOM 4058 C CA . VAL A 1 533 ? 12.584 31.066 60.530 1.00 19.04 ? 529 VAL A CA 1 ATOM 4059 C C . VAL A 1 533 ? 11.110 31.503 60.468 1.00 18.50 ? 529 VAL A C 1 ATOM 4060 O O . VAL A 1 533 ? 10.795 32.465 59.795 1.00 19.92 ? 529 VAL A O 1 ATOM 4061 C CB . VAL A 1 533 ? 13.448 32.189 61.122 1.00 20.63 ? 529 VAL A CB 1 ATOM 4062 C CG1 . VAL A 1 533 ? 12.859 32.698 62.490 1.00 21.82 ? 529 VAL A CG1 1 ATOM 4063 C CG2 . VAL A 1 533 ? 14.897 31.733 61.317 1.00 22.90 ? 529 VAL A CG2 1 ATOM 4064 N N . VAL A 1 534 ? 10.237 30.766 61.149 1.00 17.22 ? 530 VAL A N 1 ATOM 4065 C CA . VAL A 1 534 ? 8.800 30.966 60.956 1.00 18.64 ? 530 VAL A CA 1 ATOM 4066 C C . VAL A 1 534 ? 8.040 31.224 62.264 1.00 20.22 ? 530 VAL A C 1 ATOM 4067 O O . VAL A 1 534 ? 6.860 31.575 62.209 1.00 18.86 ? 530 VAL A O 1 ATOM 4068 C CB . VAL A 1 534 ? 8.242 29.762 60.165 1.00 18.00 ? 530 VAL A CB 1 ATOM 4069 C CG1 . VAL A 1 534 ? 8.031 28.562 61.031 1.00 17.60 ? 530 VAL A CG1 1 ATOM 4070 C CG2 . VAL A 1 534 ? 6.917 30.094 59.406 1.00 19.81 ? 530 VAL A CG2 1 ATOM 4071 N N . GLN A 1 535 ? 8.673 31.034 63.431 1.00 20.39 ? 531 GLN A N 1 ATOM 4072 C CA . GLN A 1 535 ? 7.854 31.220 64.662 1.00 20.83 ? 531 GLN A CA 1 ATOM 4073 C C . GLN A 1 535 ? 7.193 32.601 64.780 1.00 20.63 ? 531 GLN A C 1 ATOM 4074 O O . GLN A 1 535 ? 5.996 32.660 65.176 1.00 20.80 ? 531 GLN A O 1 ATOM 4075 C CB . GLN A 1 535 ? 8.630 30.890 65.958 1.00 20.71 ? 531 GLN A CB 1 ATOM 4076 C CG . GLN A 1 535 ? 9.043 29.431 66.100 1.00 22.11 ? 531 GLN A CG 1 ATOM 4077 C CD . GLN A 1 535 ? 10.455 29.166 65.546 1.00 25.46 ? 531 GLN A CD 1 ATOM 4078 O OE1 . GLN A 1 535 ? 10.891 29.772 64.539 1.00 25.05 ? 531 GLN A OE1 1 ATOM 4079 N NE2 . GLN A 1 535 ? 11.191 28.277 66.222 1.00 25.62 ? 531 GLN A NE2 1 ATOM 4080 N N . PRO A 1 536 ? 7.914 33.702 64.443 1.00 20.81 ? 532 PRO A N 1 ATOM 4081 C CA . PRO A 1 536 ? 7.292 35.038 64.532 1.00 21.24 ? 532 PRO A CA 1 ATOM 4082 C C . PRO A 1 536 ? 6.105 35.184 63.548 1.00 20.53 ? 532 PRO A C 1 ATOM 4083 O O . PRO A 1 536 ? 5.070 35.691 63.925 1.00 20.09 ? 532 PRO A O 1 ATOM 4084 C CB . PRO A 1 536 ? 8.421 35.999 64.223 1.00 22.17 ? 532 PRO A CB 1 ATOM 4085 C CG . PRO A 1 536 ? 9.652 35.238 64.661 1.00 23.50 ? 532 PRO A CG 1 ATOM 4086 C CD . PRO A 1 536 ? 9.382 33.800 64.259 1.00 20.75 ? 532 PRO A CD 1 ATOM 4087 N N . LEU A 1 537 ? 6.234 34.635 62.335 1.00 19.15 ? 533 LEU A N 1 ATOM 4088 C CA . LEU A 1 537 ? 5.106 34.688 61.378 1.00 19.33 ? 533 LEU A CA 1 ATOM 4089 C C . LEU A 1 537 ? 3.921 33.890 61.896 1.00 19.07 ? 533 LEU A C 1 ATOM 4090 O O . LEU A 1 537 ? 2.744 34.341 61.809 1.00 19.96 ? 533 LEU A O 1 ATOM 4091 C CB . LEU A 1 537 ? 5.560 34.106 60.012 1.00 18.23 ? 533 LEU A CB 1 ATOM 4092 C CG . LEU A 1 537 ? 6.508 34.980 59.198 1.00 20.87 ? 533 LEU A CG 1 ATOM 4093 C CD1 . LEU A 1 537 ? 7.121 34.141 58.035 1.00 22.15 ? 533 LEU A CD1 1 ATOM 4094 C CD2 . LEU A 1 537 ? 5.772 36.206 58.659 1.00 20.11 ? 533 LEU A CD2 1 ATOM 4095 N N . LEU A 1 538 ? 4.198 32.695 62.427 1.00 19.23 ? 534 LEU A N 1 ATOM 4096 C CA . LEU A 1 538 ? 3.137 31.875 63.012 1.00 18.66 ? 534 LEU A CA 1 ATOM 4097 C C . LEU A 1 538 ? 2.444 32.585 64.153 1.00 19.92 ? 534 LEU A C 1 ATOM 4098 O O . LEU A 1 538 ? 1.204 32.552 64.207 1.00 20.33 ? 534 LEU A O 1 ATOM 4099 C CB . LEU A 1 538 ? 3.644 30.529 63.530 1.00 19.36 ? 534 LEU A CB 1 ATOM 4100 C CG . LEU A 1 538 ? 4.057 29.516 62.459 1.00 20.09 ? 534 LEU A CG 1 ATOM 4101 C CD1 . LEU A 1 538 ? 4.985 28.420 63.084 1.00 21.23 ? 534 LEU A CD1 1 ATOM 4102 C CD2 . LEU A 1 538 ? 2.811 28.903 61.793 1.00 19.49 ? 534 LEU A CD2 1 ATOM 4103 N N . ALA A 1 539 ? 3.228 33.220 65.020 1.00 19.85 ? 535 ALA A N 1 ATOM 4104 C CA . ALA A 1 539 ? 2.635 33.863 66.213 1.00 20.92 ? 535 ALA A CA 1 ATOM 4105 C C . ALA A 1 539 ? 1.648 34.949 65.818 1.00 21.27 ? 535 ALA A C 1 ATOM 4106 O O . ALA A 1 539 ? 0.608 35.079 66.465 1.00 21.91 ? 535 ALA A O 1 ATOM 4107 C CB . ALA A 1 539 ? 3.704 34.437 67.094 1.00 21.54 ? 535 ALA A CB 1 ATOM 4108 N N . ALA A 1 540 ? 1.956 35.719 64.765 1.00 18.75 ? 536 ALA A N 1 ATOM 4109 C CA . ALA A 1 540 ? 1.077 36.759 64.292 1.00 19.77 ? 536 ALA A CA 1 ATOM 4110 C C . ALA A 1 540 ? -0.177 36.271 63.565 1.00 18.40 ? 536 ALA A C 1 ATOM 4111 O O . ALA A 1 540 ? -1.182 36.962 63.546 1.00 20.50 ? 536 ALA A O 1 ATOM 4112 C CB . ALA A 1 540 ? 1.834 37.632 63.376 1.00 19.70 ? 536 ALA A CB 1 ATOM 4113 N N . SER A 1 541 ? -0.108 35.106 62.927 1.00 18.31 ? 537 SER A N 1 ATOM 4114 C CA . SER A 1 541 ? -1.129 34.737 61.927 1.00 18.06 ? 537 SER A CA 1 ATOM 4115 C C . SER A 1 541 ? -2.228 33.842 62.445 1.00 17.65 ? 537 SER A C 1 ATOM 4116 O O . SER A 1 541 ? -1.949 32.952 63.234 1.00 18.15 ? 537 SER A O 1 ATOM 4117 C CB . SER A 1 541 ? -0.434 33.939 60.795 1.00 19.40 ? 537 SER A CB 1 ATOM 4118 O OG . SER A 1 541 ? 0.628 34.698 60.226 1.00 19.92 ? 537 SER A OG 1 ATOM 4119 N N . ASP A 1 542 ? -3.441 34.007 61.920 1.00 17.28 ? 538 ASP A N 1 ATOM 4120 C CA . ASP A 1 542 ? -4.524 33.026 62.169 1.00 16.45 ? 538 ASP A CA 1 ATOM 4121 C C . ASP A 1 542 ? -4.245 31.724 61.407 1.00 17.26 ? 538 ASP A C 1 ATOM 4122 O O . ASP A 1 542 ? -4.349 30.641 61.964 1.00 19.97 ? 538 ASP A O 1 ATOM 4123 C CB . ASP A 1 542 ? -5.880 33.630 61.793 1.00 17.05 ? 538 ASP A CB 1 ATOM 4124 C CG . ASP A 1 542 ? -6.181 34.863 62.606 1.00 19.53 ? 538 ASP A CG 1 ATOM 4125 O OD1 . ASP A 1 542 ? -5.807 35.933 62.140 1.00 18.86 ? 538 ASP A OD1 1 ATOM 4126 O OD2 . ASP A 1 542 ? -6.755 34.751 63.729 1.00 20.33 ? 538 ASP A OD2 1 ATOM 4127 N N . ALA A 1 543 ? -3.842 31.835 60.129 1.00 15.76 ? 539 ALA A N 1 ATOM 4128 C CA . ALA A 1 543 ? -3.537 30.656 59.328 1.00 14.77 ? 539 ALA A CA 1 ATOM 4129 C C . ALA A 1 543 ? -2.239 30.978 58.590 1.00 14.84 ? 539 ALA A C 1 ATOM 4130 O O . ALA A 1 543 ? -1.960 32.136 58.292 1.00 15.79 ? 539 ALA A O 1 ATOM 4131 C CB . ALA A 1 543 ? -4.680 30.367 58.304 1.00 15.02 ? 539 ALA A CB 1 ATOM 4132 N N . LEU A 1 544 ? -1.450 29.939 58.346 1.00 15.17 ? 540 LEU A N 1 ATOM 4133 C CA . LEU A 1 544 ? -0.199 30.138 57.603 1.00 15.11 ? 540 LEU A CA 1 ATOM 4134 C C . LEU A 1 544 ? -0.038 28.962 56.660 1.00 15.23 ? 540 LEU A C 1 ATOM 4135 O O . LEU A 1 544 ? -0.134 27.791 57.068 1.00 16.36 ? 540 LEU A O 1 ATOM 4136 C CB . LEU A 1 544 ? 0.992 30.287 58.563 1.00 15.34 ? 540 LEU A CB 1 ATOM 4137 C CG . LEU A 1 544 ? 2.258 30.723 57.813 1.00 17.90 ? 540 LEU A CG 1 ATOM 4138 C CD1 . LEU A 1 544 ? 3.068 31.753 58.642 1.00 20.87 ? 540 LEU A CD1 1 ATOM 4139 C CD2 . LEU A 1 544 ? 3.148 29.467 57.456 1.00 19.83 ? 540 LEU A CD2 1 ATOM 4140 N N . VAL A 1 545 ? 0.279 29.285 55.406 1.00 14.26 ? 541 VAL A N 1 ATOM 4141 C CA . VAL A 1 545 ? 0.515 28.255 54.370 1.00 13.87 ? 541 VAL A CA 1 ATOM 4142 C C . VAL A 1 545 ? 1.940 28.397 53.833 1.00 13.66 ? 541 VAL A C 1 ATOM 4143 O O . VAL A 1 545 ? 2.384 29.519 53.456 1.00 14.57 ? 541 VAL A O 1 ATOM 4144 C CB . VAL A 1 545 ? -0.422 28.523 53.196 1.00 13.14 ? 541 VAL A CB 1 ATOM 4145 C CG1 . VAL A 1 545 ? -0.147 27.560 52.024 1.00 15.11 ? 541 VAL A CG1 1 ATOM 4146 C CG2 . VAL A 1 545 ? -1.931 28.430 53.594 1.00 15.01 ? 541 VAL A CG2 1 ATOM 4147 N N . ALA A 1 546 ? 2.658 27.279 53.739 1.00 14.25 ? 542 ALA A N 1 ATOM 4148 C CA . ALA A 1 546 ? 3.954 27.261 53.052 1.00 14.12 ? 542 ALA A CA 1 ATOM 4149 C C . ALA A 1 546 ? 3.603 26.931 51.598 1.00 13.91 ? 542 ALA A C 1 ATOM 4150 O O . ALA A 1 546 ? 3.169 25.814 51.257 1.00 14.99 ? 542 ALA A O 1 ATOM 4151 C CB . ALA A 1 546 ? 4.836 26.172 53.683 1.00 15.36 ? 542 ALA A CB 1 ATOM 4152 N N . ALA A 1 547 ? 3.778 27.944 50.727 1.00 13.60 ? 543 ALA A N 1 ATOM 4153 C CA . ALA A 1 547 ? 3.438 27.779 49.306 1.00 13.99 ? 543 ALA A CA 1 ATOM 4154 C C . ALA A 1 547 ? 4.675 27.500 48.437 1.00 14.23 ? 543 ALA A C 1 ATOM 4155 O O . ALA A 1 547 ? 4.521 27.354 47.221 1.00 14.04 ? 543 ALA A O 1 ATOM 4156 C CB . ALA A 1 547 ? 2.718 29.056 48.768 1.00 14.32 ? 543 ALA A CB 1 ATOM 4157 N N . TRP A 1 548 ? 5.852 27.449 49.052 1.00 13.69 ? 544 TRP A N 1 ATOM 4158 C CA . TRP A 1 548 ? 7.108 27.244 48.323 1.00 12.85 ? 544 TRP A CA 1 ATOM 4159 C C . TRP A 1 548 ? 7.242 28.266 47.183 1.00 13.34 ? 544 TRP A C 1 ATOM 4160 O O . TRP A 1 548 ? 7.072 29.456 47.421 1.00 13.02 ? 544 TRP A O 1 ATOM 4161 C CB . TRP A 1 548 ? 7.206 25.804 47.804 1.00 13.06 ? 544 TRP A CB 1 ATOM 4162 C CG . TRP A 1 548 ? 6.823 24.824 48.898 1.00 14.20 ? 544 TRP A CG 1 ATOM 4163 C CD1 . TRP A 1 548 ? 5.658 24.114 48.946 1.00 15.54 ? 544 TRP A CD1 1 ATOM 4164 C CD2 . TRP A 1 548 ? 7.540 24.551 50.108 1.00 14.21 ? 544 TRP A CD2 1 ATOM 4165 N NE1 . TRP A 1 548 ? 5.611 23.357 50.125 1.00 15.70 ? 544 TRP A NE1 1 ATOM 4166 C CE2 . TRP A 1 548 ? 6.765 23.567 50.827 1.00 13.16 ? 544 TRP A CE2 1 ATOM 4167 C CE3 . TRP A 1 548 ? 8.775 24.974 50.624 1.00 16.47 ? 544 TRP A CE3 1 ATOM 4168 C CZ2 . TRP A 1 548 ? 7.152 23.071 52.094 1.00 17.35 ? 544 TRP A CZ2 1 ATOM 4169 C CZ3 . TRP A 1 548 ? 9.183 24.458 51.920 1.00 18.06 ? 544 TRP A CZ3 1 ATOM 4170 C CH2 . TRP A 1 548 ? 8.374 23.498 52.601 1.00 18.15 ? 544 TRP A CH2 1 ATOM 4171 N N . LEU A 1 549 ? 7.627 27.791 45.974 1.00 12.64 ? 545 LEU A N 1 ATOM 4172 C CA . LEU A 1 549 ? 7.799 28.721 44.813 1.00 10.85 ? 545 LEU A CA 1 ATOM 4173 C C . LEU A 1 549 ? 6.829 28.224 43.720 1.00 12.18 ? 545 LEU A C 1 ATOM 4174 O O . LEU A 1 549 ? 7.194 27.398 42.827 1.00 12.56 ? 545 LEU A O 1 ATOM 4175 C CB . LEU A 1 549 ? 9.251 28.723 44.305 1.00 12.07 ? 545 LEU A CB 1 ATOM 4176 C CG . LEU A 1 549 ? 10.212 29.201 45.415 1.00 12.66 ? 545 LEU A CG 1 ATOM 4177 C CD1 . LEU A 1 549 ? 11.674 28.922 44.963 1.00 13.83 ? 545 LEU A CD1 1 ATOM 4178 C CD2 . LEU A 1 549 ? 10.060 30.697 45.709 1.00 16.48 ? 545 LEU A CD2 1 ATOM 4179 N N . PRO A 1 550 ? 5.557 28.626 43.812 1.00 12.02 ? 546 PRO A N 1 ATOM 4180 C CA . PRO A 1 550 ? 4.527 27.888 43.088 1.00 12.44 ? 546 PRO A CA 1 ATOM 4181 C C . PRO A 1 550 ? 4.440 28.126 41.583 1.00 12.79 ? 546 PRO A C 1 ATOM 4182 O O . PRO A 1 550 ? 3.703 27.370 40.922 1.00 12.79 ? 546 PRO A O 1 ATOM 4183 C CB . PRO A 1 550 ? 3.230 28.303 43.796 1.00 13.34 ? 546 PRO A CB 1 ATOM 4184 C CG . PRO A 1 550 ? 3.545 29.761 44.319 1.00 11.79 ? 546 PRO A CG 1 ATOM 4185 C CD . PRO A 1 550 ? 5.010 29.664 44.723 1.00 11.56 ? 546 PRO A CD 1 ATOM 4186 N N . GLY A 1 551 ? 5.180 29.098 41.047 1.00 12.54 ? 547 GLY A N 1 ATOM 4187 C CA . GLY A 1 551 ? 5.248 29.273 39.580 1.00 12.52 ? 547 GLY A CA 1 ATOM 4188 C C . GLY A 1 551 ? 4.223 30.295 39.060 1.00 12.78 ? 547 GLY A C 1 ATOM 4189 O O . GLY A 1 551 ? 3.752 31.196 39.799 1.00 14.01 ? 547 GLY A O 1 ATOM 4190 N N . SER A 1 552 ? 3.907 30.157 37.778 1.00 11.94 ? 548 SER A N 1 ATOM 4191 C CA . SER A 1 552 ? 3.104 31.183 37.111 1.00 12.15 ? 548 SER A CA 1 ATOM 4192 C C . SER A 1 552 ? 1.593 31.138 37.476 1.00 12.21 ? 548 SER A C 1 ATOM 4193 O O . SER A 1 552 ? 0.932 32.155 37.265 1.00 13.91 ? 548 SER A O 1 ATOM 4194 C CB . SER A 1 552 ? 3.299 31.105 35.597 1.00 12.84 ? 548 SER A CB 1 ATOM 4195 O OG . SER A 1 552 ? 2.948 29.841 35.074 1.00 13.51 ? 548 SER A OG 1 ATOM 4196 N N . GLU A 1 553 ? 1.107 30.044 38.034 1.00 12.20 ? 549 GLU A N 1 ATOM 4197 C CA . GLU A 1 553 ? -0.372 29.892 38.156 1.00 13.43 ? 549 GLU A CA 1 ATOM 4198 C C . GLU A 1 553 ? -0.823 30.118 39.581 1.00 13.80 ? 549 GLU A C 1 ATOM 4199 O O . GLU A 1 553 ? -1.027 29.202 40.387 1.00 14.49 ? 549 GLU A O 1 ATOM 4200 C CB . GLU A 1 553 ? -0.778 28.478 37.653 1.00 13.24 ? 549 GLU A CB 1 ATOM 4201 C CG . GLU A 1 553 ? -0.346 28.266 36.172 1.00 12.55 ? 549 GLU A CG 1 ATOM 4202 C CD . GLU A 1 553 ? -0.654 29.431 35.240 1.00 13.56 ? 549 GLU A CD 1 ATOM 4203 O OE1 . GLU A 1 553 ? -1.800 29.912 35.249 1.00 16.25 ? 549 GLU A OE1 1 ATOM 4204 O OE2 . GLU A 1 553 ? 0.267 29.811 34.453 1.00 14.91 ? 549 GLU A OE2 1 ATOM 4205 N N . GLY A 1 554 ? -0.919 31.383 39.923 1.00 14.10 ? 550 GLY A N 1 ATOM 4206 C CA . GLY A 1 554 ? -1.297 31.791 41.283 1.00 14.12 ? 550 GLY A CA 1 ATOM 4207 C C . GLY A 1 554 ? -2.674 31.317 41.694 1.00 14.02 ? 550 GLY A C 1 ATOM 4208 O O . GLY A 1 554 ? -2.966 31.290 42.919 1.00 14.79 ? 550 GLY A O 1 ATOM 4209 N N . GLN A 1 555 ? -3.519 30.953 40.732 1.00 13.27 ? 551 GLN A N 1 ATOM 4210 C CA . GLN A 1 555 ? -4.817 30.410 41.134 1.00 14.08 ? 551 GLN A CA 1 ATOM 4211 C C . GLN A 1 555 ? -4.697 29.101 41.886 1.00 15.25 ? 551 GLN A C 1 ATOM 4212 O O . GLN A 1 555 ? -5.643 28.712 42.559 1.00 15.20 ? 551 GLN A O 1 ATOM 4213 C CB . GLN A 1 555 ? -5.774 30.273 39.950 1.00 15.05 ? 551 GLN A CB 1 ATOM 4214 C CG . GLN A 1 555 ? -6.155 31.651 39.400 1.00 16.11 ? 551 GLN A CG 1 ATOM 4215 C CD . GLN A 1 555 ? -6.861 31.558 38.082 1.00 20.42 ? 551 GLN A CD 1 ATOM 4216 O OE1 . GLN A 1 555 ? -8.113 31.751 37.986 1.00 23.36 ? 551 GLN A OE1 1 ATOM 4217 N NE2 . GLN A 1 555 ? -6.119 31.189 37.061 1.00 18.29 ? 551 GLN A NE2 1 ATOM 4218 N N . GLY A 1 556 ? -3.573 28.409 41.775 1.00 14.00 ? 552 GLY A N 1 ATOM 4219 C CA . GLY A 1 556 ? -3.331 27.211 42.629 1.00 14.40 ? 552 GLY A CA 1 ATOM 4220 C C . GLY A 1 556 ? -3.437 27.559 44.103 1.00 15.21 ? 552 GLY A C 1 ATOM 4221 O O . GLY A 1 556 ? -3.892 26.739 44.941 1.00 14.98 ? 552 GLY A O 1 ATOM 4222 N N . VAL A 1 557 ? -2.952 28.746 44.432 1.00 13.81 ? 553 VAL A N 1 ATOM 4223 C CA . VAL A 1 557 ? -2.987 29.201 45.844 1.00 14.60 ? 553 VAL A CA 1 ATOM 4224 C C . VAL A 1 557 ? -4.435 29.471 46.278 1.00 14.66 ? 553 VAL A C 1 ATOM 4225 O O . VAL A 1 557 ? -4.875 28.977 47.322 1.00 15.54 ? 553 VAL A O 1 ATOM 4226 C CB . VAL A 1 557 ? -2.117 30.458 46.052 1.00 14.12 ? 553 VAL A CB 1 ATOM 4227 C CG1 . VAL A 1 557 ? -2.225 30.960 47.530 1.00 15.71 ? 553 VAL A CG1 1 ATOM 4228 C CG2 . VAL A 1 557 ? -0.635 30.166 45.693 1.00 15.05 ? 553 VAL A CG2 1 ATOM 4229 N N . THR A 1 558 ? -5.166 30.261 45.495 1.00 14.49 ? 554 THR A N 1 ATOM 4230 C CA . THR A 1 558 ? -6.538 30.623 45.892 1.00 14.74 ? 554 THR A CA 1 ATOM 4231 C C . THR A 1 558 ? -7.479 29.414 45.789 1.00 15.74 ? 554 THR A C 1 ATOM 4232 O O . THR A 1 558 ? -8.506 29.378 46.488 1.00 15.76 ? 554 THR A O 1 ATOM 4233 C CB . THR A 1 558 ? -7.098 31.784 45.047 1.00 14.96 ? 554 THR A CB 1 ATOM 4234 O OG1 . THR A 1 558 ? -6.863 31.529 43.637 1.00 15.09 ? 554 THR A OG1 1 ATOM 4235 C CG2 . THR A 1 558 ? -6.345 33.074 45.385 1.00 15.67 ? 554 THR A CG2 1 ATOM 4236 N N . ASP A 1 559 ? -7.170 28.417 44.954 1.00 13.87 ? 555 ASP A N 1 ATOM 4237 C CA . ASP A 1 559 ? -7.980 27.190 44.904 1.00 14.96 ? 555 ASP A CA 1 ATOM 4238 C C . ASP A 1 559 ? -8.092 26.522 46.261 1.00 16.77 ? 555 ASP A C 1 ATOM 4239 O O . ASP A 1 559 ? -9.147 25.982 46.589 1.00 18.20 ? 555 ASP A O 1 ATOM 4240 C CB . ASP A 1 559 ? -7.394 26.203 43.887 1.00 15.18 ? 555 ASP A CB 1 ATOM 4241 C CG . ASP A 1 559 ? -7.744 26.565 42.439 1.00 15.37 ? 555 ASP A CG 1 ATOM 4242 O OD1 . ASP A 1 559 ? -8.564 27.466 42.147 1.00 16.88 ? 555 ASP A OD1 1 ATOM 4243 O OD2 . ASP A 1 559 ? -7.177 25.865 41.571 1.00 17.96 ? 555 ASP A OD2 1 ATOM 4244 N N . ALA A 1 560 ? -7.014 26.534 47.059 1.00 14.14 ? 556 ALA A N 1 ATOM 4245 C CA . ALA A 1 560 ? -7.073 25.999 48.400 1.00 15.47 ? 556 ALA A CA 1 ATOM 4246 C C . ALA A 1 560 ? -7.544 27.074 49.409 1.00 15.19 ? 556 ALA A C 1 ATOM 4247 O O . ALA A 1 560 ? -8.319 26.742 50.334 1.00 15.62 ? 556 ALA A O 1 ATOM 4248 C CB . ALA A 1 560 ? -5.713 25.456 48.808 1.00 17.34 ? 556 ALA A CB 1 ATOM 4249 N N . LEU A 1 561 ? -7.126 28.341 49.253 1.00 14.63 ? 557 LEU A N 1 ATOM 4250 C CA . LEU A 1 561 ? -7.545 29.329 50.271 1.00 14.58 ? 557 LEU A CA 1 ATOM 4251 C C . LEU A 1 561 ? -9.058 29.465 50.333 1.00 15.57 ? 557 LEU A C 1 ATOM 4252 O O . LEU A 1 561 ? -9.608 29.705 51.447 1.00 16.23 ? 557 LEU A O 1 ATOM 4253 C CB . LEU A 1 561 ? -6.995 30.712 49.915 1.00 15.45 ? 557 LEU A CB 1 ATOM 4254 C CG . LEU A 1 561 ? -5.490 30.868 50.118 1.00 14.91 ? 557 LEU A CG 1 ATOM 4255 C CD1 . LEU A 1 561 ? -5.114 32.316 49.662 1.00 16.18 ? 557 LEU A CD1 1 ATOM 4256 C CD2 . LEU A 1 561 ? -4.989 30.600 51.514 1.00 16.49 ? 557 LEU A CD2 1 ATOM 4257 N N . PHE A 1 562 ? -9.733 29.336 49.182 1.00 15.25 ? 558 PHE A N 1 ATOM 4258 C CA . PHE A 1 562 ? -11.212 29.521 49.135 1.00 15.93 ? 558 PHE A CA 1 ATOM 4259 C C . PHE A 1 562 ? -12.001 28.213 49.137 1.00 16.95 ? 558 PHE A C 1 ATOM 4260 O O . PHE A 1 562 ? -13.237 28.247 48.944 1.00 18.92 ? 558 PHE A O 1 ATOM 4261 C CB . PHE A 1 562 ? -11.613 30.415 47.961 1.00 16.07 ? 558 PHE A CB 1 ATOM 4262 C CG . PHE A 1 562 ? -11.106 31.833 48.086 1.00 15.83 ? 558 PHE A CG 1 ATOM 4263 C CD1 . PHE A 1 562 ? -11.581 32.678 49.100 1.00 17.18 ? 558 PHE A CD1 1 ATOM 4264 C CD2 . PHE A 1 562 ? -10.174 32.336 47.210 1.00 19.35 ? 558 PHE A CD2 1 ATOM 4265 C CE1 . PHE A 1 562 ? -11.139 33.998 49.215 1.00 18.57 ? 558 PHE A CE1 1 ATOM 4266 C CE2 . PHE A 1 562 ? -9.688 33.689 47.338 1.00 19.72 ? 558 PHE A CE2 1 ATOM 4267 C CZ . PHE A 1 562 ? -10.177 34.514 48.367 1.00 18.05 ? 558 PHE A CZ 1 ATOM 4268 N N . GLY A 1 563 ? -11.290 27.112 49.356 1.00 17.05 ? 559 GLY A N 1 ATOM 4269 C CA . GLY A 1 563 ? -11.940 25.803 49.557 1.00 17.89 ? 559 GLY A CA 1 ATOM 4270 C C . GLY A 1 563 ? -12.464 25.088 48.320 1.00 19.09 ? 559 GLY A C 1 ATOM 4271 O O . GLY A 1 563 ? -13.256 24.152 48.471 1.00 19.84 ? 559 GLY A O 1 ATOM 4272 N N . ASP A 1 564 ? -12.054 25.501 47.118 1.00 18.59 ? 560 ASP A N 1 ATOM 4273 C CA . ASP A 1 564 ? -12.443 24.704 45.944 1.00 19.85 ? 560 ASP A CA 1 ATOM 4274 C C . ASP A 1 564 ? -11.847 23.312 46.058 1.00 19.64 ? 560 ASP A C 1 ATOM 4275 O O . ASP A 1 564 ? -12.450 22.334 45.596 1.00 19.42 ? 560 ASP A O 1 ATOM 4276 C CB . ASP A 1 564 ? -11.987 25.365 44.655 1.00 20.30 ? 560 ASP A CB 1 ATOM 4277 C CG . ASP A 1 564 ? -12.821 26.604 44.311 1.00 24.55 ? 560 ASP A CG 1 ATOM 4278 O OD1 . ASP A 1 564 ? -13.908 26.768 44.879 1.00 30.11 ? 560 ASP A OD1 1 ATOM 4279 O OD2 . ASP A 1 564 ? -12.404 27.363 43.451 1.00 35.97 ? 560 ASP A OD2 1 ATOM 4280 N N . PHE A 1 565 ? -10.654 23.223 46.642 1.00 18.41 ? 561 PHE A N 1 ATOM 4281 C CA . PHE A 1 565 ? -10.028 21.959 46.986 1.00 19.15 ? 561 PHE A CA 1 ATOM 4282 C C . PHE A 1 565 ? -9.543 22.024 48.423 1.00 18.96 ? 561 PHE A C 1 ATOM 4283 O O . PHE A 1 565 ? -9.307 23.127 48.970 1.00 20.34 ? 561 PHE A O 1 ATOM 4284 C CB . PHE A 1 565 ? -8.807 21.685 46.072 1.00 19.29 ? 561 PHE A CB 1 ATOM 4285 C CG . PHE A 1 565 ? -9.183 21.531 44.664 1.00 20.66 ? 561 PHE A CG 1 ATOM 4286 C CD1 . PHE A 1 565 ? -9.296 22.649 43.842 1.00 20.06 ? 561 PHE A CD1 1 ATOM 4287 C CD2 . PHE A 1 565 ? -9.470 20.264 44.139 1.00 23.10 ? 561 PHE A CD2 1 ATOM 4288 C CE1 . PHE A 1 565 ? -9.704 22.520 42.505 1.00 23.26 ? 561 PHE A CE1 1 ATOM 4289 C CE2 . PHE A 1 565 ? -9.877 20.161 42.808 1.00 24.56 ? 561 PHE A CE2 1 ATOM 4290 C CZ . PHE A 1 565 ? -9.964 21.272 42.001 1.00 23.59 ? 561 PHE A CZ 1 ATOM 4291 N N . GLY A 1 566 ? -9.395 20.864 49.061 1.00 19.74 ? 562 GLY A N 1 ATOM 4292 C CA . GLY A 1 566 ? -8.796 20.850 50.385 1.00 19.33 ? 562 GLY A CA 1 ATOM 4293 C C . GLY A 1 566 ? -7.270 20.871 50.338 1.00 20.33 ? 562 GLY A C 1 ATOM 4294 O O . GLY A 1 566 ? -6.658 20.484 49.327 1.00 22.68 ? 562 GLY A O 1 ATOM 4295 N N . PHE A 1 567 ? -6.659 21.346 51.407 1.00 18.16 ? 563 PHE A N 1 ATOM 4296 C CA . PHE A 1 567 ? -5.183 21.240 51.557 1.00 17.37 ? 563 PHE A CA 1 ATOM 4297 C C . PHE A 1 567 ? -4.786 19.783 51.717 1.00 19.16 ? 563 PHE A C 1 ATOM 4298 O O . PHE A 1 567 ? -5.411 19.044 52.514 1.00 20.45 ? 563 PHE A O 1 ATOM 4299 C CB . PHE A 1 567 ? -4.689 22.014 52.751 1.00 17.86 ? 563 PHE A CB 1 ATOM 4300 C CG . PHE A 1 567 ? -4.664 23.496 52.519 1.00 15.42 ? 563 PHE A CG 1 ATOM 4301 C CD1 . PHE A 1 567 ? -5.762 24.310 52.828 1.00 18.61 ? 563 PHE A CD1 1 ATOM 4302 C CD2 . PHE A 1 567 ? -3.506 24.076 51.991 1.00 14.58 ? 563 PHE A CD2 1 ATOM 4303 C CE1 . PHE A 1 567 ? -5.736 25.689 52.606 1.00 18.54 ? 563 PHE A CE1 1 ATOM 4304 C CE2 . PHE A 1 567 ? -3.473 25.455 51.766 1.00 16.55 ? 563 PHE A CE2 1 ATOM 4305 C CZ . PHE A 1 567 ? -4.557 26.270 52.098 1.00 16.24 ? 563 PHE A CZ 1 ATOM 4306 N N . THR A 1 568 ? -3.762 19.353 50.972 1.00 17.87 ? 564 THR A N 1 ATOM 4307 C CA . THR A 1 568 ? -3.308 17.960 51.051 1.00 19.04 ? 564 THR A CA 1 ATOM 4308 C C . THR A 1 568 ? -1.776 17.853 51.133 1.00 18.09 ? 564 THR A C 1 ATOM 4309 O O . THR A 1 568 ? -1.219 16.769 51.392 1.00 19.15 ? 564 THR A O 1 ATOM 4310 C CB . THR A 1 568 ? -3.787 17.135 49.866 1.00 19.17 ? 564 THR A CB 1 ATOM 4311 O OG1 . THR A 1 568 ? -3.445 17.786 48.615 1.00 19.86 ? 564 THR A OG1 1 ATOM 4312 C CG2 . THR A 1 568 ? -5.317 16.941 49.875 1.00 22.04 ? 564 THR A CG2 1 ATOM 4313 N N . GLY A 1 569 ? -1.080 18.951 50.853 1.00 17.67 ? 565 GLY A N 1 ATOM 4314 C CA . GLY A 1 569 ? 0.388 18.902 50.851 1.00 17.10 ? 565 GLY A CA 1 ATOM 4315 C C . GLY A 1 569 ? 0.966 18.531 52.207 1.00 18.05 ? 565 GLY A C 1 ATOM 4316 O O . GLY A 1 569 ? 0.402 18.874 53.287 1.00 17.64 ? 565 GLY A O 1 ATOM 4317 N N . ARG A 1 570 ? 2.123 17.871 52.183 1.00 16.97 ? 566 ARG A N 1 ATOM 4318 C CA . ARG A 1 570 ? 2.851 17.501 53.437 1.00 18.00 ? 566 ARG A CA 1 ATOM 4319 C C . ARG A 1 570 ? 4.311 17.873 53.317 1.00 17.06 ? 566 ARG A C 1 ATOM 4320 O O . ARG A 1 570 ? 4.896 17.722 52.204 1.00 17.50 ? 566 ARG A O 1 ATOM 4321 C CB . ARG A 1 570 ? 2.724 15.971 53.709 1.00 20.06 ? 566 ARG A CB 1 ATOM 4322 C CG . ARG A 1 570 ? 1.239 15.535 53.767 1.00 22.32 ? 566 ARG A CG 1 ATOM 4323 C CD . ARG A 1 570 ? 0.938 14.150 54.346 1.00 34.73 ? 566 ARG A CD 1 ATOM 4324 N NE . ARG A 1 570 ? 1.784 13.086 53.844 1.00 40.12 ? 566 ARG A NE 1 ATOM 4325 C CZ A ARG A 1 570 ? 1.599 12.399 52.713 0.60 41.77 ? 566 ARG A CZ 1 ATOM 4326 C CZ B ARG A 1 570 ? 2.668 12.376 54.544 0.40 37.98 ? 566 ARG A CZ 1 ATOM 4327 N NH1 A ARG A 1 570 ? 0.604 12.680 51.868 0.60 38.41 ? 566 ARG A NH1 1 ATOM 4328 N NH1 B ARG A 1 570 ? 2.841 12.548 55.845 0.40 38.25 ? 566 ARG A NH1 1 ATOM 4329 N NH2 A ARG A 1 570 ? 2.453 11.425 52.421 0.60 42.50 ? 566 ARG A NH2 1 ATOM 4330 N NH2 B ARG A 1 570 ? 3.370 11.455 53.913 0.40 37.70 ? 566 ARG A NH2 1 ATOM 4331 N N . LEU A 1 571 ? 4.924 18.326 54.420 1.00 16.12 ? 567 LEU A N 1 ATOM 4332 C CA . LEU A 1 571 ? 6.308 18.823 54.340 1.00 17.39 ? 567 LEU A CA 1 ATOM 4333 C C . LEU A 1 571 ? 7.204 17.729 53.739 1.00 18.02 ? 567 LEU A C 1 ATOM 4334 O O . LEU A 1 571 ? 7.187 16.570 54.175 1.00 19.08 ? 567 LEU A O 1 ATOM 4335 C CB . LEU A 1 571 ? 6.842 19.185 55.707 1.00 17.86 ? 567 LEU A CB 1 ATOM 4336 C CG . LEU A 1 571 ? 6.233 20.429 56.360 1.00 17.54 ? 567 LEU A CG 1 ATOM 4337 C CD1 . LEU A 1 571 ? 6.943 20.701 57.642 1.00 18.67 ? 567 LEU A CD1 1 ATOM 4338 C CD2 . LEU A 1 571 ? 6.370 21.727 55.446 1.00 19.14 ? 567 LEU A CD2 1 ATOM 4339 N N . PRO A 1 572 ? 7.969 18.070 52.690 1.00 17.29 ? 568 PRO A N 1 ATOM 4340 C CA . PRO A 1 572 ? 8.952 17.131 52.147 1.00 17.19 ? 568 PRO A CA 1 ATOM 4341 C C . PRO A 1 572 ? 10.311 17.320 52.815 1.00 17.99 ? 568 PRO A C 1 ATOM 4342 O O . PRO A 1 572 ? 11.281 16.680 52.381 1.00 19.46 ? 568 PRO A O 1 ATOM 4343 C CB . PRO A 1 572 ? 9.024 17.555 50.657 1.00 16.90 ? 568 PRO A CB 1 ATOM 4344 C CG . PRO A 1 572 ? 8.935 19.064 50.755 1.00 16.64 ? 568 PRO A CG 1 ATOM 4345 C CD . PRO A 1 572 ? 7.860 19.304 51.879 1.00 16.83 ? 568 PRO A CD 1 ATOM 4346 N N . ARG A 1 573 ? 10.419 18.191 53.821 1.00 19.21 ? 569 ARG A N 1 ATOM 4347 C CA . ARG A 1 573 ? 11.668 18.536 54.514 1.00 21.36 ? 569 ARG A CA 1 ATOM 4348 C C . ARG A 1 573 ? 11.296 18.766 55.950 1.00 21.32 ? 569 ARG A C 1 ATOM 4349 O O . ARG A 1 573 ? 10.174 19.159 56.231 1.00 21.43 ? 569 ARG A O 1 ATOM 4350 C CB . ARG A 1 573 ? 12.201 19.945 54.067 1.00 23.85 ? 569 ARG A CB 1 ATOM 4351 C CG . ARG A 1 573 ? 12.556 20.114 52.694 1.00 26.86 ? 569 ARG A CG 1 ATOM 4352 C CD . ARG A 1 573 ? 13.521 21.218 52.561 1.00 21.15 ? 569 ARG A CD 1 ATOM 4353 N NE . ARG A 1 573 ? 14.735 20.957 53.338 1.00 21.75 ? 569 ARG A NE 1 ATOM 4354 C CZ . ARG A 1 573 ? 15.694 20.104 52.986 1.00 20.46 ? 569 ARG A CZ 1 ATOM 4355 N NH1 . ARG A 1 573 ? 15.663 19.462 51.806 1.00 19.95 ? 569 ARG A NH1 1 ATOM 4356 N NH2 . ARG A 1 573 ? 16.715 19.938 53.815 1.00 21.43 ? 569 ARG A NH2 1 ATOM 4357 N N . THR A 1 574 ? 12.267 18.624 56.835 1.00 20.33 ? 570 THR A N 1 ATOM 4358 C CA . THR A 1 574 ? 12.128 19.065 58.222 1.00 21.36 ? 570 THR A CA 1 ATOM 4359 C C . THR A 1 574 ? 12.056 20.590 58.332 1.00 19.85 ? 570 THR A C 1 ATOM 4360 O O . THR A 1 574 ? 12.799 21.308 57.680 1.00 20.03 ? 570 THR A O 1 ATOM 4361 C CB . THR A 1 574 ? 13.349 18.506 58.991 1.00 21.18 ? 570 THR A CB 1 ATOM 4362 O OG1 . THR A 1 574 ? 13.268 17.088 58.943 1.00 21.66 ? 570 THR A OG1 1 ATOM 4363 C CG2 . THR A 1 574 ? 13.387 19.051 60.465 1.00 24.80 ? 570 THR A CG2 1 ATOM 4364 N N . TRP A 1 575 ? 11.159 21.113 59.187 1.00 19.92 ? 571 TRP A N 1 ATOM 4365 C CA . TRP A 1 575 ? 11.152 22.525 59.494 1.00 18.56 ? 571 TRP A CA 1 ATOM 4366 C C . TRP A 1 575 ? 11.854 22.704 60.827 1.00 20.76 ? 571 TRP A C 1 ATOM 4367 O O . TRP A 1 575 ? 11.354 22.245 61.847 1.00 21.99 ? 571 TRP A O 1 ATOM 4368 C CB . TRP A 1 575 ? 9.705 23.112 59.549 1.00 19.83 ? 571 TRP A CB 1 ATOM 4369 C CG . TRP A 1 575 ? 9.720 24.570 59.206 1.00 16.90 ? 571 TRP A CG 1 ATOM 4370 C CD1 . TRP A 1 575 ? 10.336 25.586 59.867 1.00 17.21 ? 571 TRP A CD1 1 ATOM 4371 C CD2 . TRP A 1 575 ? 9.097 25.159 58.050 1.00 17.38 ? 571 TRP A CD2 1 ATOM 4372 N NE1 . TRP A 1 575 ? 10.131 26.805 59.217 1.00 18.09 ? 571 TRP A NE1 1 ATOM 4373 C CE2 . TRP A 1 575 ? 9.378 26.545 58.090 1.00 16.23 ? 571 TRP A CE2 1 ATOM 4374 C CE3 . TRP A 1 575 ? 8.351 24.621 56.984 1.00 19.52 ? 571 TRP A CE3 1 ATOM 4375 C CZ2 . TRP A 1 575 ? 8.922 27.424 57.112 1.00 17.27 ? 571 TRP A CZ2 1 ATOM 4376 C CZ3 . TRP A 1 575 ? 7.909 25.504 55.965 1.00 18.01 ? 571 TRP A CZ3 1 ATOM 4377 C CH2 . TRP A 1 575 ? 8.187 26.881 56.061 1.00 15.30 ? 571 TRP A CH2 1 ATOM 4378 N N . PHE A 1 576 ? 12.997 23.336 60.786 1.00 20.68 ? 572 PHE A N 1 ATOM 4379 C CA . PHE A 1 576 ? 13.831 23.518 62.001 1.00 21.58 ? 572 PHE A CA 1 ATOM 4380 C C . PHE A 1 576 ? 13.200 24.568 62.941 1.00 23.16 ? 572 PHE A C 1 ATOM 4381 O O . PHE A 1 576 ? 12.455 25.482 62.539 1.00 22.79 ? 572 PHE A O 1 ATOM 4382 C CB . PHE A 1 576 ? 15.247 23.935 61.601 1.00 21.88 ? 572 PHE A CB 1 ATOM 4383 C CG . PHE A 1 576 ? 15.269 25.167 60.712 1.00 21.27 ? 572 PHE A CG 1 ATOM 4384 C CD1 . PHE A 1 576 ? 15.150 26.431 61.240 1.00 20.03 ? 572 PHE A CD1 1 ATOM 4385 C CD2 . PHE A 1 576 ? 15.350 25.018 59.304 1.00 22.21 ? 572 PHE A CD2 1 ATOM 4386 C CE1 . PHE A 1 576 ? 15.156 27.578 60.424 1.00 20.77 ? 572 PHE A CE1 1 ATOM 4387 C CE2 . PHE A 1 576 ? 15.335 26.160 58.468 1.00 20.36 ? 572 PHE A CE2 1 ATOM 4388 C CZ . PHE A 1 576 ? 15.197 27.403 58.991 1.00 19.84 ? 572 PHE A CZ 1 ATOM 4389 N N . LYS A 1 577 ? 13.552 24.461 64.233 1.00 23.84 ? 573 LYS A N 1 ATOM 4390 C CA . LYS A 1 577 ? 13.257 25.561 65.167 1.00 23.00 ? 573 LYS A CA 1 ATOM 4391 C C . LYS A 1 577 ? 14.263 26.719 65.068 1.00 23.43 ? 573 LYS A C 1 ATOM 4392 O O . LYS A 1 577 ? 13.911 27.901 65.237 1.00 24.10 ? 573 LYS A O 1 ATOM 4393 C CB . LYS A 1 577 ? 13.228 25.025 66.620 1.00 22.67 ? 573 LYS A CB 1 ATOM 4394 C CG . LYS A 1 577 ? 12.187 23.977 66.847 1.00 24.53 ? 573 LYS A CG 1 ATOM 4395 C CD . LYS A 1 577 ? 12.218 23.473 68.349 1.00 27.29 ? 573 LYS A CD 1 ATOM 4396 C CE . LYS A 1 577 ? 11.052 22.619 68.629 1.00 27.85 ? 573 LYS A CE 1 ATOM 4397 N NZ . LYS A 1 577 ? 11.159 22.141 70.069 1.00 30.91 ? 573 LYS A NZ 1 ATOM 4398 N N . SER A 1 578 ? 15.540 26.380 64.841 1.00 23.18 ? 574 SER A N 1 ATOM 4399 C CA . SER A 1 578 ? 16.606 27.350 64.792 1.00 24.14 ? 574 SER A CA 1 ATOM 4400 C C . SER A 1 578 ? 17.712 26.891 63.798 1.00 22.95 ? 574 SER A C 1 ATOM 4401 O O . SER A 1 578 ? 17.939 25.695 63.694 1.00 23.47 ? 574 SER A O 1 ATOM 4402 C CB . SER A 1 578 ? 17.258 27.474 66.207 1.00 24.46 ? 574 SER A CB 1 ATOM 4403 O OG . SER A 1 578 ? 18.486 28.205 66.082 1.00 31.15 ? 574 SER A OG 1 ATOM 4404 N N . VAL A 1 579 ? 18.356 27.843 63.114 1.00 23.94 ? 575 VAL A N 1 ATOM 4405 C CA . VAL A 1 579 ? 19.444 27.487 62.167 1.00 24.50 ? 575 VAL A CA 1 ATOM 4406 C C . VAL A 1 579 ? 20.612 26.866 62.949 1.00 26.00 ? 575 VAL A C 1 ATOM 4407 O O . VAL A 1 579 ? 21.397 26.120 62.383 1.00 26.05 ? 575 VAL A O 1 ATOM 4408 C CB . VAL A 1 579 ? 19.917 28.645 61.244 1.00 24.53 ? 575 VAL A CB 1 ATOM 4409 C CG1 . VAL A 1 579 ? 18.727 29.124 60.363 1.00 25.31 ? 575 VAL A CG1 1 ATOM 4410 C CG2 . VAL A 1 579 ? 20.516 29.852 62.014 1.00 24.67 ? 575 VAL A CG2 1 ATOM 4411 N N . ASP A 1 580 ? 20.675 27.130 64.259 1.00 26.74 ? 576 ASP A N 1 ATOM 4412 C CA . ASP A 1 580 ? 21.736 26.520 65.087 1.00 27.85 ? 576 ASP A CA 1 ATOM 4413 C C . ASP A 1 580 ? 21.588 25.012 65.162 1.00 27.20 ? 576 ASP A C 1 ATOM 4414 O O . ASP A 1 580 ? 22.540 24.303 65.528 1.00 28.11 ? 576 ASP A O 1 ATOM 4415 C CB . ASP A 1 580 ? 21.628 27.027 66.525 1.00 29.44 ? 576 ASP A CB 1 ATOM 4416 C CG . ASP A 1 580 ? 21.940 28.461 66.663 1.00 33.81 ? 576 ASP A CG 1 ATOM 4417 O OD1 . ASP A 1 580 ? 22.585 29.055 65.770 1.00 41.89 ? 576 ASP A OD1 1 ATOM 4418 O OD2 . ASP A 1 580 ? 21.535 29.031 67.712 1.00 39.95 ? 576 ASP A OD2 1 ATOM 4419 N N . GLN A 1 581 ? 20.413 24.485 64.872 1.00 24.78 ? 577 GLN A N 1 ATOM 4420 C CA . GLN A 1 581 ? 20.225 23.043 64.852 1.00 23.96 ? 577 GLN A CA 1 ATOM 4421 C C . GLN A 1 581 ? 20.866 22.366 63.647 1.00 24.34 ? 577 GLN A C 1 ATOM 4422 O O . GLN A 1 581 ? 21.022 21.147 63.628 1.00 25.06 ? 577 GLN A O 1 ATOM 4423 C CB . GLN A 1 581 ? 18.741 22.653 64.888 1.00 24.98 ? 577 GLN A CB 1 ATOM 4424 C CG . GLN A 1 581 ? 18.017 23.146 66.170 1.00 24.61 ? 577 GLN A CG 1 ATOM 4425 C CD . GLN A 1 581 ? 16.556 22.866 66.075 1.00 28.23 ? 577 GLN A CD 1 ATOM 4426 O OE1 . GLN A 1 581 ? 15.885 23.357 65.141 1.00 26.06 ? 577 GLN A OE1 1 ATOM 4427 N NE2 . GLN A 1 581 ? 16.036 22.026 66.971 1.00 25.71 ? 577 GLN A NE2 1 ATOM 4428 N N . LEU A 1 582 ? 21.184 23.161 62.627 1.00 24.17 ? 578 LEU A N 1 ATOM 4429 C CA . LEU A 1 582 ? 21.484 22.565 61.328 1.00 23.69 ? 578 LEU A CA 1 ATOM 4430 C C . LEU A 1 582 ? 22.916 22.024 61.207 1.00 24.84 ? 578 LEU A C 1 ATOM 4431 O O . LEU A 1 582 ? 23.838 22.654 61.715 1.00 26.19 ? 578 LEU A O 1 ATOM 4432 C CB . LEU A 1 582 ? 21.204 23.575 60.207 1.00 23.13 ? 578 LEU A CB 1 ATOM 4433 C CG . LEU A 1 582 ? 19.703 23.957 60.107 1.00 22.28 ? 578 LEU A CG 1 ATOM 4434 C CD1 . LEU A 1 582 ? 19.570 25.079 59.017 1.00 22.41 ? 578 LEU A CD1 1 ATOM 4435 C CD2 . LEU A 1 582 ? 18.749 22.800 59.913 1.00 21.30 ? 578 LEU A CD2 1 ATOM 4436 N N . PRO A 1 583 ? 23.081 20.925 60.448 1.00 25.44 ? 579 PRO A N 1 ATOM 4437 C CA . PRO A 1 583 ? 22.068 20.125 59.765 1.00 26.62 ? 579 PRO A CA 1 ATOM 4438 C C . PRO A 1 583 ? 21.295 19.256 60.739 1.00 28.44 ? 579 PRO A C 1 ATOM 4439 O O . PRO A 1 583 ? 21.889 18.746 61.733 1.00 28.70 ? 579 PRO A O 1 ATOM 4440 C CB . PRO A 1 583 ? 22.876 19.228 58.809 1.00 26.70 ? 579 PRO A CB 1 ATOM 4441 C CG . PRO A 1 583 ? 24.235 19.120 59.483 1.00 26.27 ? 579 PRO A CG 1 ATOM 4442 C CD . PRO A 1 583 ? 24.462 20.469 60.126 1.00 26.00 ? 579 PRO A CD 1 ATOM 4443 N N . MET A 1 584 ? 20.010 19.081 60.469 1.00 28.20 ? 580 MET A N 1 ATOM 4444 C CA . MET A 1 584 ? 19.154 18.257 61.318 1.00 29.38 ? 580 MET A CA 1 ATOM 4445 C C . MET A 1 584 ? 18.169 17.486 60.498 1.00 30.97 ? 580 MET A C 1 ATOM 4446 O O . MET A 1 584 ? 17.258 18.059 59.860 1.00 30.54 ? 580 MET A O 1 ATOM 4447 C CB . MET A 1 584 ? 18.454 19.124 62.379 1.00 28.64 ? 580 MET A CB 1 ATOM 4448 C CG . MET A 1 584 ? 17.534 18.327 63.318 1.00 29.51 ? 580 MET A CG 1 ATOM 4449 S SD . MET A 1 584 ? 16.816 19.428 64.561 1.00 27.43 ? 580 MET A SD 1 ATOM 4450 C CE . MET A 1 584 ? 15.615 20.342 63.494 1.00 24.91 ? 580 MET A CE 1 ATOM 4451 N N . ASN A 1 585 ? 18.349 16.168 60.505 1.00 32.65 ? 581 ASN A N 1 ATOM 4452 C CA . ASN A 1 585 ? 17.613 15.299 59.613 1.00 35.67 ? 581 ASN A CA 1 ATOM 4453 C C . ASN A 1 585 ? 16.874 14.168 60.317 1.00 37.68 ? 581 ASN A C 1 ATOM 4454 O O . ASN A 1 585 ? 17.354 13.682 61.309 1.00 38.62 ? 581 ASN A O 1 ATOM 4455 C CB . ASN A 1 585 ? 18.601 14.731 58.571 1.00 35.11 ? 581 ASN A CB 1 ATOM 4456 C CG . ASN A 1 585 ? 18.931 15.761 57.487 1.00 32.34 ? 581 ASN A CG 1 ATOM 4457 O OD1 . ASN A 1 585 ? 18.081 16.087 56.672 1.00 34.04 ? 581 ASN A OD1 1 ATOM 4458 N ND2 . ASN A 1 585 ? 20.142 16.293 57.508 1.00 29.23 ? 581 ASN A ND2 1 ATOM 4459 N N . VAL A 1 586 ? 15.720 13.778 59.768 1.00 41.45 ? 582 VAL A N 1 ATOM 4460 C CA . VAL A 1 586 ? 14.838 12.767 60.379 1.00 45.45 ? 582 VAL A CA 1 ATOM 4461 C C . VAL A 1 586 ? 15.628 11.485 60.498 1.00 46.75 ? 582 VAL A C 1 ATOM 4462 O O . VAL A 1 586 ? 15.991 10.884 59.495 1.00 48.51 ? 582 VAL A O 1 ATOM 4463 C CB . VAL A 1 586 ? 13.426 12.652 59.659 1.00 44.78 ? 582 VAL A CB 1 ATOM 4464 C CG1 . VAL A 1 586 ? 13.496 12.043 58.264 1.00 47.76 ? 582 VAL A CG1 1 ATOM 4465 C CG2 . VAL A 1 586 ? 12.430 11.872 60.515 1.00 48.52 ? 582 VAL A CG2 1 ATOM 4466 N N . GLY A 1 587 ? 15.977 11.127 61.733 1.00 48.10 ? 583 GLY A N 1 ATOM 4467 C CA . GLY A 1 587 ? 16.899 10.039 61.993 1.00 48.28 ? 583 GLY A CA 1 ATOM 4468 C C . GLY A 1 587 ? 17.987 10.421 62.973 1.00 48.90 ? 583 GLY A C 1 ATOM 4469 O O . GLY A 1 587 ? 18.494 9.567 63.682 1.00 49.64 ? 583 GLY A O 1 ATOM 4470 N N . ASP A 1 588 ? 18.357 11.698 63.014 1.00 48.85 ? 584 ASP A N 1 ATOM 4471 C CA . ASP A 1 588 ? 19.451 12.184 63.874 1.00 48.78 ? 584 ASP A CA 1 ATOM 4472 C C . ASP A 1 588 ? 19.128 12.081 65.358 1.00 49.53 ? 584 ASP A C 1 ATOM 4473 O O . ASP A 1 588 ? 17.958 11.990 65.748 1.00 49.56 ? 584 ASP A O 1 ATOM 4474 C CB . ASP A 1 588 ? 19.775 13.660 63.565 1.00 48.89 ? 584 ASP A CB 1 ATOM 4475 C CG A ASP A 1 588 ? 20.930 13.840 62.576 0.60 49.05 ? 584 ASP A CG 1 ATOM 4476 C CG B ASP A 1 588 ? 20.166 13.896 62.096 0.40 47.53 ? 584 ASP A CG 1 ATOM 4477 O OD1 A ASP A 1 588 ? 21.404 14.996 62.427 0.60 48.60 ? 584 ASP A OD1 1 ATOM 4478 O OD1 B ASP A 1 588 ? 20.455 15.063 61.764 0.40 44.55 ? 584 ASP A OD1 1 ATOM 4479 O OD2 A ASP A 1 588 ? 21.354 12.848 61.946 0.60 48.57 ? 584 ASP A OD2 1 ATOM 4480 O OD2 B ASP A 1 588 ? 20.187 12.938 61.279 0.40 45.22 ? 584 ASP A OD2 1 ATOM 4481 N N . ALA A 1 589 ? 20.169 12.144 66.186 1.00 49.75 ? 585 ALA A N 1 ATOM 4482 C CA . ALA A 1 589 ? 20.003 12.124 67.639 1.00 49.84 ? 585 ALA A CA 1 ATOM 4483 C C . ALA A 1 589 ? 19.343 13.394 68.181 1.00 49.44 ? 585 ALA A C 1 ATOM 4484 O O . ALA A 1 589 ? 18.412 13.308 68.988 1.00 50.27 ? 585 ALA A O 1 ATOM 4485 C CB . ALA A 1 589 ? 21.351 11.872 68.347 1.00 50.20 ? 585 ALA A CB 1 ATOM 4486 N N . HIS A 1 590 ? 19.827 14.565 67.767 1.00 48.00 ? 586 HIS A N 1 ATOM 4487 C CA . HIS A 1 590 ? 19.249 15.831 68.265 1.00 46.43 ? 586 HIS A CA 1 ATOM 4488 C C . HIS A 1 590 ? 17.982 16.275 67.479 1.00 43.57 ? 586 HIS A C 1 ATOM 4489 O O . HIS A 1 590 ? 17.670 17.476 67.479 1.00 44.36 ? 586 HIS A O 1 ATOM 4490 C CB . HIS A 1 590 ? 20.318 16.961 68.365 1.00 47.29 ? 586 HIS A CB 1 ATOM 4491 C CG . HIS A 1 590 ? 20.700 17.591 67.042 1.00 51.66 ? 586 HIS A CG 1 ATOM 4492 N ND1 . HIS A 1 590 ? 21.433 16.929 66.068 1.00 55.44 ? 586 HIS A ND1 1 ATOM 4493 C CD2 . HIS A 1 590 ? 20.463 18.835 66.545 1.00 54.28 ? 586 HIS A CD2 1 ATOM 4494 C CE1 . HIS A 1 590 ? 21.613 17.732 65.029 1.00 55.12 ? 586 HIS A CE1 1 ATOM 4495 N NE2 . HIS A 1 590 ? 21.034 18.894 65.294 1.00 53.55 ? 586 HIS A NE2 1 ATOM 4496 N N . TYR A 1 591 ? 17.257 15.319 66.862 1.00 40.07 ? 587 TYR A N 1 ATOM 4497 C CA . TYR A 1 591 ? 16.068 15.611 66.009 1.00 36.48 ? 587 TYR A CA 1 ATOM 4498 C C . TYR A 1 591 ? 14.908 16.252 66.771 1.00 35.09 ? 587 TYR A C 1 ATOM 4499 O O . TYR A 1 591 ? 14.050 15.552 67.340 1.00 36.09 ? 587 TYR A O 1 ATOM 4500 C CB . TYR A 1 591 ? 15.534 14.398 65.231 1.00 35.52 ? 587 TYR A CB 1 ATOM 4501 C CG . TYR A 1 591 ? 14.586 14.793 64.075 1.00 34.01 ? 587 TYR A CG 1 ATOM 4502 C CD1 . TYR A 1 591 ? 15.065 15.554 62.992 1.00 31.56 ? 587 TYR A CD1 1 ATOM 4503 C CD2 . TYR A 1 591 ? 13.237 14.396 64.057 1.00 30.33 ? 587 TYR A CD2 1 ATOM 4504 C CE1 . TYR A 1 591 ? 14.196 15.926 61.925 1.00 29.65 ? 587 TYR A CE1 1 ATOM 4505 C CE2 . TYR A 1 591 ? 12.366 14.753 62.997 1.00 29.38 ? 587 TYR A CE2 1 ATOM 4506 C CZ . TYR A 1 591 ? 12.875 15.531 61.927 1.00 28.73 ? 587 TYR A CZ 1 ATOM 4507 O OH . TYR A 1 591 ? 12.027 15.883 60.880 1.00 27.73 ? 587 TYR A OH 1 ATOM 4508 N N . ASP A 1 592 ? 14.875 17.583 66.723 1.00 31.57 ? 588 ASP A N 1 ATOM 4509 C CA . ASP A 1 592 ? 13.945 18.373 67.513 1.00 28.48 ? 588 ASP A CA 1 ATOM 4510 C C . ASP A 1 592 ? 13.296 19.413 66.562 1.00 26.87 ? 588 ASP A C 1 ATOM 4511 O O . ASP A 1 592 ? 13.594 20.596 66.650 1.00 27.04 ? 588 ASP A O 1 ATOM 4512 C CB . ASP A 1 592 ? 14.703 19.047 68.646 1.00 29.04 ? 588 ASP A CB 1 ATOM 4513 C CG . ASP A 1 592 ? 13.800 19.854 69.564 1.00 28.36 ? 588 ASP A CG 1 ATOM 4514 O OD1 . ASP A 1 592 ? 12.603 19.548 69.618 1.00 30.97 ? 588 ASP A OD1 1 ATOM 4515 O OD2 . ASP A 1 592 ? 14.310 20.808 70.187 1.00 34.47 ? 588 ASP A OD2 1 ATOM 4516 N N . PRO A 1 593 ? 12.411 18.936 65.679 1.00 25.74 ? 589 PRO A N 1 ATOM 4517 C CA . PRO A 1 593 ? 11.890 19.909 64.682 1.00 25.89 ? 589 PRO A CA 1 ATOM 4518 C C . PRO A 1 593 ? 10.752 20.778 65.191 1.00 25.77 ? 589 PRO A C 1 ATOM 4519 O O . PRO A 1 593 ? 9.999 20.367 66.114 1.00 26.54 ? 589 PRO A O 1 ATOM 4520 C CB . PRO A 1 593 ? 11.355 18.987 63.584 1.00 24.89 ? 589 PRO A CB 1 ATOM 4521 C CG . PRO A 1 593 ? 10.835 17.758 64.333 1.00 27.51 ? 589 PRO A CG 1 ATOM 4522 C CD . PRO A 1 593 ? 11.848 17.583 65.469 1.00 25.33 ? 589 PRO A CD 1 ATOM 4523 N N . LEU A 1 594 ? 10.584 21.959 64.571 1.00 23.74 ? 590 LEU A N 1 ATOM 4524 C CA . LEU A 1 594 ? 9.343 22.685 64.700 1.00 21.78 ? 590 LEU A CA 1 ATOM 4525 C C . LEU A 1 594 ? 8.167 21.897 64.076 1.00 21.99 ? 590 LEU A C 1 ATOM 4526 O O . LEU A 1 594 ? 7.074 21.806 64.676 1.00 23.03 ? 590 LEU A O 1 ATOM 4527 C CB . LEU A 1 594 ? 9.481 24.091 64.106 1.00 21.44 ? 590 LEU A CB 1 ATOM 4528 C CG . LEU A 1 594 ? 8.275 24.996 64.386 1.00 21.38 ? 590 LEU A CG 1 ATOM 4529 C CD1 . LEU A 1 594 ? 8.182 25.376 65.865 1.00 24.15 ? 590 LEU A CD1 1 ATOM 4530 C CD2 . LEU A 1 594 ? 8.486 26.274 63.577 1.00 22.82 ? 590 LEU A CD2 1 ATOM 4531 N N . PHE A 1 595 ? 8.348 21.349 62.853 1.00 20.23 ? 591 PHE A N 1 ATOM 4532 C CA . PHE A 1 595 ? 7.372 20.532 62.185 1.00 21.35 ? 591 PHE A CA 1 ATOM 4533 C C . PHE A 1 595 ? 8.213 19.441 61.539 1.00 23.03 ? 591 PHE A C 1 ATOM 4534 O O . PHE A 1 595 ? 9.216 19.728 60.827 1.00 22.29 ? 591 PHE A O 1 ATOM 4535 C CB . PHE A 1 595 ? 6.597 21.294 61.070 1.00 21.32 ? 591 PHE A CB 1 ATOM 4536 C CG . PHE A 1 595 ? 5.801 22.480 61.547 1.00 20.40 ? 591 PHE A CG 1 ATOM 4537 C CD1 . PHE A 1 595 ? 4.593 22.284 62.236 1.00 23.00 ? 591 PHE A CD1 1 ATOM 4538 C CD2 . PHE A 1 595 ? 6.274 23.773 61.323 1.00 19.47 ? 591 PHE A CD2 1 ATOM 4539 C CE1 . PHE A 1 595 ? 3.855 23.369 62.684 1.00 21.95 ? 591 PHE A CE1 1 ATOM 4540 C CE2 . PHE A 1 595 ? 5.547 24.871 61.748 1.00 24.22 ? 591 PHE A CE2 1 ATOM 4541 C CZ . PHE A 1 595 ? 4.327 24.677 62.421 1.00 20.58 ? 591 PHE A CZ 1 ATOM 4542 N N . ARG A 1 596 ? 7.833 18.194 61.799 1.00 22.84 ? 592 ARG A N 1 ATOM 4543 C CA . ARG A 1 596 ? 8.580 17.061 61.274 1.00 23.27 ? 592 ARG A CA 1 ATOM 4544 C C . ARG A 1 596 ? 8.298 16.900 59.764 1.00 22.73 ? 592 ARG A C 1 ATOM 4545 O O . ARG A 1 596 ? 7.246 17.374 59.228 1.00 21.11 ? 592 ARG A O 1 ATOM 4546 C CB . ARG A 1 596 ? 8.182 15.781 62.062 1.00 24.84 ? 592 ARG A CB 1 ATOM 4547 C CG . ARG A 1 596 ? 6.830 15.265 61.641 1.00 29.34 ? 592 ARG A CG 1 ATOM 4548 C CD . ARG A 1 596 ? 6.035 14.398 62.634 1.00 39.29 ? 592 ARG A CD 1 ATOM 4549 N NE . ARG A 1 596 ? 4.623 14.410 62.176 1.00 46.02 ? 592 ARG A NE 1 ATOM 4550 C CZ . ARG A 1 596 ? 3.652 15.235 62.612 1.00 47.23 ? 592 ARG A CZ 1 ATOM 4551 N NH1 . ARG A 1 596 ? 2.435 15.151 62.078 1.00 47.17 ? 592 ARG A NH1 1 ATOM 4552 N NH2 . ARG A 1 596 ? 3.865 16.119 63.590 1.00 45.80 ? 592 ARG A NH2 1 ATOM 4553 N N . LEU A 1 597 ? 9.222 16.224 59.063 1.00 22.69 ? 593 LEU A N 1 ATOM 4554 C CA . LEU A 1 597 ? 8.917 15.735 57.737 1.00 22.57 ? 593 LEU A CA 1 ATOM 4555 C C . LEU A 1 597 ? 7.586 15.007 57.696 1.00 22.19 ? 593 LEU A C 1 ATOM 4556 O O . LEU A 1 597 ? 7.323 14.129 58.557 1.00 22.07 ? 593 LEU A O 1 ATOM 4557 C CB . LEU A 1 597 ? 10.043 14.831 57.201 1.00 24.29 ? 593 LEU A CB 1 ATOM 4558 C CG . LEU A 1 597 ? 9.868 14.582 55.685 1.00 27.48 ? 593 LEU A CG 1 ATOM 4559 C CD1 . LEU A 1 597 ? 11.197 14.629 54.959 1.00 30.41 ? 593 LEU A CD1 1 ATOM 4560 C CD2 . LEU A 1 597 ? 9.147 13.315 55.384 1.00 30.21 ? 593 LEU A CD2 1 ATOM 4561 N N . GLY A 1 598 ? 6.726 15.346 56.729 1.00 19.74 ? 594 GLY A N 1 ATOM 4562 C CA . GLY A 1 598 ? 5.459 14.694 56.547 1.00 18.96 ? 594 GLY A CA 1 ATOM 4563 C C . GLY A 1 598 ? 4.308 15.439 57.233 1.00 18.52 ? 594 GLY A C 1 ATOM 4564 O O . GLY A 1 598 ? 3.165 15.090 57.002 1.00 20.55 ? 594 GLY A O 1 ATOM 4565 N N . TYR A 1 599 ? 4.630 16.496 57.972 1.00 19.55 ? 595 TYR A N 1 ATOM 4566 C CA . TYR A 1 599 ? 3.572 17.294 58.678 1.00 20.03 ? 595 TYR A CA 1 ATOM 4567 C C . TYR A 1 599 ? 2.741 18.065 57.666 1.00 20.58 ? 595 TYR A C 1 ATOM 4568 O O . TYR A 1 599 ? 3.274 18.579 56.676 1.00 20.07 ? 595 TYR A O 1 ATOM 4569 C CB . TYR A 1 599 ? 4.224 18.265 59.665 1.00 19.35 ? 595 TYR A CB 1 ATOM 4570 C CG . TYR A 1 599 ? 3.251 19.219 60.314 1.00 20.66 ? 595 TYR A CG 1 ATOM 4571 C CD1 . TYR A 1 599 ? 3.003 20.480 59.752 1.00 23.69 ? 595 TYR A CD1 1 ATOM 4572 C CD2 . TYR A 1 599 ? 2.579 18.876 61.487 1.00 24.90 ? 595 TYR A CD2 1 ATOM 4573 C CE1 . TYR A 1 599 ? 2.124 21.364 60.352 1.00 26.22 ? 595 TYR A CE1 1 ATOM 4574 C CE2 . TYR A 1 599 ? 1.660 19.772 62.073 1.00 25.21 ? 595 TYR A CE2 1 ATOM 4575 C CZ . TYR A 1 599 ? 1.446 21.002 61.488 1.00 25.02 ? 595 TYR A CZ 1 ATOM 4576 O OH . TYR A 1 599 ? 0.578 21.943 62.062 1.00 26.11 ? 595 TYR A OH 1 ATOM 4577 N N . GLY A 1 600 ? 1.444 18.143 57.879 1.00 19.77 ? 596 GLY A N 1 ATOM 4578 C CA . GLY A 1 600 ? 0.632 19.075 57.098 1.00 20.45 ? 596 GLY A CA 1 ATOM 4579 C C . GLY A 1 600 ? -0.818 18.981 57.534 1.00 21.41 ? 596 GLY A C 1 ATOM 4580 O O . GLY A 1 600 ? -1.395 17.881 57.590 1.00 22.62 ? 596 GLY A O 1 ATOM 4581 N N . LEU A 1 601 ? -1.414 20.117 57.842 1.00 19.97 ? 597 LEU A N 1 ATOM 4582 C CA . LEU A 1 601 ? -2.845 20.115 58.165 1.00 20.06 ? 597 LEU A CA 1 ATOM 4583 C C . LEU A 1 601 ? -3.718 19.978 56.927 1.00 21.41 ? 597 LEU A C 1 ATOM 4584 O O . LEU A 1 601 ? -3.296 20.234 55.790 1.00 21.45 ? 597 LEU A O 1 ATOM 4585 C CB . LEU A 1 601 ? -3.168 21.404 58.912 1.00 19.40 ? 597 LEU A CB 1 ATOM 4586 C CG . LEU A 1 601 ? -2.357 21.657 60.170 1.00 20.56 ? 597 LEU A CG 1 ATOM 4587 C CD1 . LEU A 1 601 ? -2.757 23.013 60.782 1.00 21.28 ? 597 LEU A CD1 1 ATOM 4588 C CD2 . LEU A 1 601 ? -2.576 20.517 61.191 1.00 21.19 ? 597 LEU A CD2 1 ATOM 4589 N N . THR A 1 602 ? -4.965 19.570 57.115 1.00 21.62 ? 598 THR A N 1 ATOM 4590 C CA . THR A 1 602 ? -5.832 19.390 55.976 1.00 22.35 ? 598 THR A CA 1 ATOM 4591 C C . THR A 1 602 ? -7.093 20.226 56.128 1.00 23.28 ? 598 THR A C 1 ATOM 4592 O O . THR A 1 602 ? -7.411 20.682 57.246 1.00 23.99 ? 598 THR A O 1 ATOM 4593 C CB . THR A 1 602 ? -6.221 17.919 55.771 1.00 24.49 ? 598 THR A CB 1 ATOM 4594 O OG1 . THR A 1 602 ? -6.788 17.436 56.993 1.00 25.80 ? 598 THR A OG1 1 ATOM 4595 C CG2 . THR A 1 602 ? -5.009 17.078 55.423 1.00 25.81 ? 598 THR A CG2 1 ATOM 4596 N N . THR A 1 603 ? -7.757 20.460 55.010 1.00 22.64 ? 599 THR A N 1 ATOM 4597 C CA . THR A 1 603 ? -9.105 20.988 55.024 1.00 23.75 ? 599 THR A CA 1 ATOM 4598 C C . THR A 1 603 ? -9.918 20.178 54.064 1.00 25.59 ? 599 THR A C 1 ATOM 4599 O O . THR A 1 603 ? -9.381 19.423 53.250 1.00 25.29 ? 599 THR A O 1 ATOM 4600 C CB . THR A 1 603 ? -9.161 22.462 54.578 1.00 22.91 ? 599 THR A CB 1 ATOM 4601 O OG1 . THR A 1 603 ? -8.580 22.562 53.256 1.00 21.57 ? 599 THR A OG1 1 ATOM 4602 C CG2 . THR A 1 603 ? -8.404 23.387 55.574 1.00 22.10 ? 599 THR A CG2 1 ATOM 4603 N N . ASN A 1 604 ? -11.246 20.295 54.184 1.00 27.50 ? 600 ASN A N 1 ATOM 4604 C CA . ASN A 1 604 ? -12.169 19.702 53.217 1.00 30.79 ? 600 ASN A CA 1 ATOM 4605 C C . ASN A 1 604 ? -12.689 20.736 52.227 1.00 31.21 ? 600 ASN A C 1 ATOM 4606 O O . ASN A 1 604 ? -13.016 21.859 52.628 1.00 30.96 ? 600 ASN A O 1 ATOM 4607 C CB . ASN A 1 604 ? -13.349 19.039 53.968 1.00 31.73 ? 600 ASN A CB 1 ATOM 4608 C CG . ASN A 1 604 ? -12.900 17.801 54.694 1.00 36.98 ? 600 ASN A CG 1 ATOM 4609 O OD1 . ASN A 1 604 ? -12.157 17.007 54.132 1.00 43.04 ? 600 ASN A OD1 1 ATOM 4610 N ND2 . ASN A 1 604 ? -13.318 17.629 55.923 1.00 43.98 ? 600 ASN A ND2 1 ATOM 4611 N N . ALA A 1 605 ? -12.796 20.351 50.955 1.00 32.37 ? 601 ALA A N 1 ATOM 4612 C CA . ALA A 1 605 ? -13.389 21.229 49.941 1.00 34.89 ? 601 ALA A CA 1 ATOM 4613 C C . ALA A 1 605 ? -14.761 21.754 50.410 1.00 36.54 ? 601 ALA A C 1 ATOM 4614 O O . ALA A 1 605 ? -15.546 21.004 51.010 1.00 36.91 ? 601 ALA A O 1 ATOM 4615 C CB . ALA A 1 605 ? -13.512 20.504 48.623 1.00 34.11 ? 601 ALA A CB 1 ATOM 4616 N N . THR A 1 606 ? -15.002 23.049 50.224 1.00 38.26 ? 602 THR A N 1 ATOM 4617 C CA . THR A 1 606 ? -16.314 23.649 50.492 1.00 40.27 ? 602 THR A CA 1 ATOM 4618 C C . THR A 1 606 ? -16.997 23.891 49.171 1.00 41.21 ? 602 THR A C 1 ATOM 4619 O O . THR A 1 606 ? -17.180 22.926 48.418 1.00 43.48 ? 602 THR A O 1 ATOM 4620 C CB . THR A 1 606 ? -16.233 24.952 51.344 1.00 41.32 ? 602 THR A CB 1 ATOM 4621 O OG1 . THR A 1 606 ? -15.510 25.982 50.653 1.00 39.86 ? 602 THR A OG1 1 ATOM 4622 C CG2 . THR A 1 606 ? -15.556 24.670 52.684 1.00 42.08 ? 602 THR A CG2 1 HETATM 4623 C C1 . NAG B 2 . ? 34.541 25.251 50.576 1.00 31.88 ? 701 NAG A C1 1 HETATM 4624 C C2 . NAG B 2 . ? 35.663 24.969 49.558 1.00 33.21 ? 701 NAG A C2 1 HETATM 4625 C C3 . NAG B 2 . ? 36.950 25.654 50.020 1.00 37.13 ? 701 NAG A C3 1 HETATM 4626 C C4 . NAG B 2 . ? 36.653 27.120 50.283 1.00 40.64 ? 701 NAG A C4 1 HETATM 4627 C C5 . NAG B 2 . ? 35.600 27.204 51.389 1.00 39.75 ? 701 NAG A C5 1 HETATM 4628 C C6 . NAG B 2 . ? 35.318 28.651 51.780 1.00 41.38 ? 701 NAG A C6 1 HETATM 4629 C C7 . NAG B 2 . ? 35.530 22.862 48.336 1.00 33.11 ? 701 NAG A C7 1 HETATM 4630 C C8 . NAG B 2 . ? 35.774 21.387 48.339 1.00 29.99 ? 701 NAG A C8 1 HETATM 4631 N N2 . NAG B 2 . ? 35.870 23.558 49.437 1.00 31.20 ? 701 NAG A N2 1 HETATM 4632 O O3 . NAG B 2 . ? 37.852 25.598 48.958 1.00 40.37 ? 701 NAG A O3 1 HETATM 4633 O O4 . NAG B 2 . ? 37.815 27.885 50.555 1.00 42.46 ? 701 NAG A O4 1 HETATM 4634 O O5 . NAG B 2 . ? 34.424 26.617 50.852 1.00 36.23 ? 701 NAG A O5 1 HETATM 4635 O O6 . NAG B 2 . ? 34.921 29.406 50.642 1.00 42.66 ? 701 NAG A O6 1 HETATM 4636 O O7 . NAG B 2 . ? 34.994 23.386 47.341 1.00 32.05 ? 701 NAG A O7 1 HETATM 4637 C C1 . NAG C 2 . ? 21.040 36.524 55.706 1.00 51.20 ? 702 NAG A C1 1 HETATM 4638 C C2 . NAG C 2 . ? 21.579 37.949 55.808 1.00 57.31 ? 702 NAG A C2 1 HETATM 4639 C C3 . NAG C 2 . ? 21.083 38.714 54.582 1.00 56.16 ? 702 NAG A C3 1 HETATM 4640 C C4 . NAG C 2 . ? 21.827 38.072 53.409 1.00 55.80 ? 702 NAG A C4 1 HETATM 4641 C C5 . NAG C 2 . ? 21.514 36.564 53.355 1.00 54.43 ? 702 NAG A C5 1 HETATM 4642 C C6 . NAG C 2 . ? 22.245 35.840 52.211 1.00 52.28 ? 702 NAG A C6 1 HETATM 4643 C C7 . NAG C 2 . ? 22.432 38.462 58.044 1.00 66.82 ? 702 NAG A C7 1 HETATM 4644 C C8 . NAG C 2 . ? 23.764 37.844 57.659 1.00 66.76 ? 702 NAG A C8 1 HETATM 4645 N N2 . NAG C 2 . ? 21.409 38.513 57.147 1.00 62.99 ? 702 NAG A N2 1 HETATM 4646 O O3 . NAG C 2 . ? 21.408 40.080 54.639 1.00 54.95 ? 702 NAG A O3 1 HETATM 4647 O O4 . NAG C 2 . ? 21.528 38.707 52.177 1.00 57.29 ? 702 NAG A O4 1 HETATM 4648 O O5 . NAG C 2 . ? 21.757 35.939 54.625 1.00 52.65 ? 702 NAG A O5 1 HETATM 4649 O O6 . NAG C 2 . ? 23.496 35.317 52.600 1.00 50.54 ? 702 NAG A O6 1 HETATM 4650 O O7 . NAG C 2 . ? 22.331 38.911 59.187 1.00 69.05 ? 702 NAG A O7 1 HETATM 4651 C C1 . NAG D 2 . ? -12.888 16.466 56.674 1.00 53.86 ? 703 NAG A C1 1 HETATM 4652 C C2 . NAG D 2 . ? -13.131 16.703 58.163 1.00 58.34 ? 703 NAG A C2 1 HETATM 4653 C C3 . NAG D 2 . ? -12.475 15.562 58.921 1.00 58.15 ? 703 NAG A C3 1 HETATM 4654 C C4 . NAG D 2 . ? -13.407 14.392 58.665 1.00 58.53 ? 703 NAG A C4 1 HETATM 4655 C C5 . NAG D 2 . ? -13.605 14.132 57.166 1.00 58.56 ? 703 NAG A C5 1 HETATM 4656 C C6 . NAG D 2 . ? -14.977 13.499 56.991 1.00 59.75 ? 703 NAG A C6 1 HETATM 4657 C C7 . NAG D 2 . ? -13.675 19.036 58.648 1.00 62.61 ? 703 NAG A C7 1 HETATM 4658 C C8 . NAG D 2 . ? -13.217 20.305 59.303 1.00 62.98 ? 703 NAG A C8 1 HETATM 4659 N N2 . NAG D 2 . ? -12.806 18.013 58.717 1.00 61.36 ? 703 NAG A N2 1 HETATM 4660 O O3 . NAG D 2 . ? -12.461 15.864 60.290 1.00 57.32 ? 703 NAG A O3 1 HETATM 4661 O O4 . NAG D 2 . ? -12.935 13.230 59.314 1.00 59.69 ? 703 NAG A O4 1 HETATM 4662 O O5 . NAG D 2 . ? -13.545 15.259 56.271 1.00 56.60 ? 703 NAG A O5 1 HETATM 4663 O O6 . NAG D 2 . ? -14.851 12.585 55.934 1.00 61.45 ? 703 NAG A O6 1 HETATM 4664 O O7 . NAG D 2 . ? -14.783 18.993 58.077 1.00 62.41 ? 703 NAG A O7 1 HETATM 4665 C C2 A BGC E 3 . ? 24.234 24.782 37.008 0.80 10.78 ? 704 BGC A C2 1 HETATM 4666 C C2 B BGC E 3 . ? 25.013 26.262 34.110 0.20 26.39 ? 704 BGC A C2 1 HETATM 4667 C C3 A BGC E 3 . ? 23.620 23.629 36.206 0.80 10.97 ? 704 BGC A C3 1 HETATM 4668 C C3 B BGC E 3 . ? 23.741 25.609 33.596 0.20 26.94 ? 704 BGC A C3 1 HETATM 4669 C C4 A BGC E 3 . ? 23.018 24.171 34.910 0.80 11.11 ? 704 BGC A C4 1 HETATM 4670 C C4 B BGC E 3 . ? 23.562 24.320 34.369 0.20 26.57 ? 704 BGC A C4 1 HETATM 4671 C C5 A BGC E 3 . ? 24.210 24.898 34.218 0.80 11.39 ? 704 BGC A C5 1 HETATM 4672 C C5 B BGC E 3 . ? 23.221 24.669 35.808 0.20 25.36 ? 704 BGC A C5 1 HETATM 4673 C C6 A BGC E 3 . ? 23.884 25.400 32.803 0.80 13.72 ? 704 BGC A C6 1 HETATM 4674 C C6 B BGC E 3 . ? 23.665 23.546 36.735 0.20 24.55 ? 704 BGC A C6 1 HETATM 4675 C C1 A BGC E 3 . ? 25.200 25.641 36.181 0.80 14.73 ? 704 BGC A C1 1 HETATM 4676 C C1 B BGC E 3 . ? 25.045 26.312 35.638 0.20 25.94 ? 704 BGC A C1 1 HETATM 4677 O O1 A BGC E 3 . ? 25.494 26.848 36.832 0.80 19.67 ? 704 BGC A O1 1 HETATM 4678 O O1 B BGC E 3 . ? 26.104 25.499 36.169 0.20 18.17 ? 704 BGC A O1 1 HETATM 4679 O O2 A BGC E 3 . ? 24.992 24.257 38.107 0.80 11.74 ? 704 BGC A O2 1 HETATM 4680 O O2 B BGC E 3 . ? 25.130 27.592 33.596 0.20 29.18 ? 704 BGC A O2 1 HETATM 4681 O O3 A BGC E 3 . ? 22.529 23.086 36.955 0.80 12.97 ? 704 BGC A O3 1 HETATM 4682 O O3 B BGC E 3 . ? 23.819 25.292 32.204 0.20 26.97 ? 704 BGC A O3 1 HETATM 4683 O O4 A BGC E 3 . ? 22.575 23.077 34.107 0.80 12.62 ? 704 BGC A O4 1 HETATM 4684 O O4 B BGC E 3 . ? 22.516 23.521 33.802 0.20 26.23 ? 704 BGC A O4 1 HETATM 4685 O O5 A BGC E 3 . ? 24.568 26.057 34.946 0.80 13.25 ? 704 BGC A O5 1 HETATM 4686 O O5 B BGC E 3 . ? 23.792 25.926 36.210 0.20 25.92 ? 704 BGC A O5 1 HETATM 4687 O O6 A BGC E 3 . ? 22.997 26.544 32.813 0.80 12.05 ? 704 BGC A O6 1 HETATM 4688 O O6 B BGC E 3 . ? 22.679 22.496 36.731 0.20 21.23 ? 704 BGC A O6 1 HETATM 4689 C C2 A BGC F 3 . ? 24.243 31.335 33.406 0.80 17.40 ? 705 BGC A C2 1 HETATM 4690 C C2 B BGC F 3 . ? 26.302 30.860 35.130 0.20 17.84 ? 705 BGC A C2 1 HETATM 4691 C C3 A BGC F 3 . ? 25.455 32.263 33.588 0.80 18.16 ? 705 BGC A C3 1 HETATM 4692 C C3 B BGC F 3 . ? 25.308 31.938 34.746 0.20 21.02 ? 705 BGC A C3 1 HETATM 4693 C C4 A BGC F 3 . ? 26.128 31.902 34.906 0.80 17.18 ? 705 BGC A C4 1 HETATM 4694 C C4 B BGC F 3 . ? 24.500 31.363 33.587 0.20 21.47 ? 705 BGC A C4 1 HETATM 4695 C C5 A BGC F 3 . ? 26.497 30.446 34.866 0.80 21.09 ? 705 BGC A C5 1 HETATM 4696 C C5 B BGC F 3 . ? 23.765 30.106 34.043 0.20 22.00 ? 705 BGC A C5 1 HETATM 4697 C C6 A BGC F 3 . ? 27.287 30.121 36.130 0.80 21.22 ? 705 BGC A C6 1 HETATM 4698 C C6 B BGC F 3 . ? 24.133 28.904 33.182 0.20 21.52 ? 705 BGC A C6 1 HETATM 4699 C C1 A BGC F 3 . ? 24.599 29.869 33.602 0.80 16.94 ? 705 BGC A C1 1 HETATM 4700 C C1 B BGC F 3 . ? 25.523 29.637 35.605 0.20 17.03 ? 705 BGC A C1 1 HETATM 4701 O O1 A BGC F 3 . ? 23.350 29.155 33.674 0.80 12.87 ? 705 BGC A O1 1 HETATM 4702 O O1 B BGC F 3 . ? 25.970 28.505 34.887 0.20 10.61 ? 705 BGC A O1 1 HETATM 4703 O O2 A BGC F 3 . ? 23.733 31.583 32.093 0.80 14.60 ? 705 BGC A O2 1 HETATM 4704 O O2 B BGC F 3 . ? 27.150 31.245 36.210 0.20 16.21 ? 705 BGC A O2 1 HETATM 4705 O O3 A BGC F 3 . ? 24.986 33.592 33.705 0.80 23.25 ? 705 BGC A O3 1 HETATM 4706 O O3 B BGC F 3 . ? 25.932 33.161 34.351 0.20 22.37 ? 705 BGC A O3 1 HETATM 4707 O O4 A BGC F 3 . ? 27.358 32.616 35.052 0.80 27.78 ? 705 BGC A O4 1 HETATM 4708 O O4 B BGC F 3 . ? 23.621 32.365 33.037 0.20 21.93 ? 705 BGC A O4 1 HETATM 4709 O O5 A BGC F 3 . ? 25.294 29.648 34.832 0.80 18.49 ? 705 BGC A O5 1 HETATM 4710 O O5 B BGC F 3 . ? 24.121 29.780 35.388 0.20 20.69 ? 705 BGC A O5 1 HETATM 4711 O O6 A BGC F 3 . ? 27.499 28.707 36.179 0.80 30.44 ? 705 BGC A O6 1 HETATM 4712 O O6 B BGC F 3 . ? 23.188 27.839 33.354 0.20 19.61 ? 705 BGC A O6 1 HETATM 4713 S S . SO4 G 4 . ? 44.994 4.132 22.115 1.00 44.89 ? 706 SO4 A S 1 HETATM 4714 O O1 . SO4 G 4 . ? 45.048 3.602 20.741 1.00 43.15 ? 706 SO4 A O1 1 HETATM 4715 O O2 . SO4 G 4 . ? 45.422 5.554 22.058 1.00 38.77 ? 706 SO4 A O2 1 HETATM 4716 O O3 . SO4 G 4 . ? 43.614 3.852 22.612 1.00 38.03 ? 706 SO4 A O3 1 HETATM 4717 O O4 . SO4 G 4 . ? 45.915 3.423 23.045 1.00 42.62 ? 706 SO4 A O4 1 HETATM 4718 O O . HOH H 5 . ? 27.646 28.096 38.064 1.00 41.50 ? 801 HOH A O 1 HETATM 4719 O O . HOH H 5 . ? 15.700 14.305 57.502 1.00 39.41 ? 802 HOH A O 1 HETATM 4720 O O . HOH H 5 . ? 39.098 28.961 44.105 1.00 42.17 ? 803 HOH A O 1 HETATM 4721 O O . HOH H 5 . ? 34.093 32.788 41.810 1.00 47.24 ? 804 HOH A O 1 HETATM 4722 O O . HOH H 5 . ? 6.437 11.910 54.714 1.00 44.05 ? 805 HOH A O 1 HETATM 4723 O O . HOH H 5 . ? 46.064 25.465 45.479 1.00 56.98 ? 806 HOH A O 1 HETATM 4724 O O . HOH H 5 . ? 38.973 30.345 43.002 1.00 44.35 ? 807 HOH A O 1 HETATM 4725 O O . HOH H 5 . ? 30.245 25.748 60.508 1.00 56.14 ? 808 HOH A O 1 HETATM 4726 O O . HOH H 5 . ? 43.596 7.776 34.449 1.00 50.57 ? 809 HOH A O 1 HETATM 4727 O O . HOH H 5 . ? 29.003 32.053 38.753 1.00 55.19 ? 810 HOH A O 1 HETATM 4728 O O . HOH H 5 . ? 39.652 21.990 46.282 1.00 41.61 ? 811 HOH A O 1 HETATM 4729 O O . HOH H 5 . ? 12.899 34.901 65.570 1.00 47.30 ? 812 HOH A O 1 HETATM 4730 O O . HOH H 5 . ? 7.921 46.280 62.806 1.00 54.83 ? 813 HOH A O 1 HETATM 4731 O O . HOH H 5 . ? -0.776 6.482 37.430 1.00 55.69 ? 814 HOH A O 1 HETATM 4732 O O . HOH H 5 . ? 16.091 16.937 7.772 1.00 49.43 ? 815 HOH A O 1 HETATM 4733 O O . HOH H 5 . ? 9.800 3.458 40.326 1.00 50.97 ? 816 HOH A O 1 HETATM 4734 O O . HOH H 5 . ? 44.368 12.698 35.802 1.00 45.07 ? 817 HOH A O 1 HETATM 4735 O O . HOH H 5 . ? -1.087 18.891 30.378 1.00 44.92 ? 818 HOH A O 1 HETATM 4736 O O . HOH H 5 . ? 29.041 34.529 48.093 1.00 41.40 ? 819 HOH A O 1 HETATM 4737 O O . HOH H 5 . ? -1.624 10.757 54.101 1.00 57.10 ? 820 HOH A O 1 HETATM 4738 O O . HOH H 5 . ? -3.941 15.284 46.498 1.00 56.23 ? 821 HOH A O 1 HETATM 4739 O O . HOH H 5 . ? -15.342 51.109 52.600 1.00 58.02 ? 822 HOH A O 1 HETATM 4740 O O . HOH H 5 . ? 17.433 31.285 11.155 1.00 53.06 ? 823 HOH A O 1 HETATM 4741 O O . HOH H 5 . ? -8.119 43.003 64.857 1.00 44.65 ? 824 HOH A O 1 HETATM 4742 O O . HOH H 5 . ? 26.459 22.152 62.505 1.00 47.49 ? 825 HOH A O 1 HETATM 4743 O O . HOH H 5 . ? 29.927 -6.406 35.543 1.00 58.27 ? 826 HOH A O 1 HETATM 4744 O O . HOH H 5 . ? -1.462 41.061 34.446 1.00 49.25 ? 827 HOH A O 1 HETATM 4745 O O . HOH H 5 . ? 13.622 46.699 52.846 1.00 51.68 ? 828 HOH A O 1 HETATM 4746 O O . HOH H 5 . ? -13.755 35.579 61.989 1.00 71.91 ? 829 HOH A O 1 HETATM 4747 O O . HOH H 5 . ? 5.759 2.670 34.849 1.00 60.80 ? 830 HOH A O 1 HETATM 4748 O O . HOH H 5 . ? 0.029 42.937 32.851 1.00 51.48 ? 831 HOH A O 1 HETATM 4749 O O . HOH H 5 . ? 27.609 -3.099 26.527 1.00 62.40 ? 832 HOH A O 1 HETATM 4750 O O . HOH H 5 . ? 33.645 27.926 54.572 1.00 51.14 ? 833 HOH A O 1 HETATM 4751 O O . HOH H 5 . ? -15.726 33.913 62.346 1.00 41.08 ? 834 HOH A O 1 HETATM 4752 O O . HOH H 5 . ? -2.421 10.009 40.281 1.00 50.84 ? 835 HOH A O 1 HETATM 4753 O O . HOH H 5 . ? -19.456 24.612 52.872 1.00 47.77 ? 836 HOH A O 1 HETATM 4754 O O . HOH H 5 . ? 46.126 10.093 17.564 1.00 45.23 ? 837 HOH A O 1 HETATM 4755 O O . HOH H 5 . ? 31.352 8.029 59.557 1.00 46.70 ? 838 HOH A O 1 HETATM 4756 O O . HOH H 5 . ? 4.839 37.955 23.334 1.00 49.45 ? 839 HOH A O 1 HETATM 4757 O O . HOH H 5 . ? 29.178 -0.265 46.513 1.00 43.79 ? 840 HOH A O 1 HETATM 4758 O O . HOH H 5 . ? 26.389 0.294 47.728 1.00 59.43 ? 841 HOH A O 1 HETATM 4759 O O . HOH H 5 . ? 13.839 29.375 68.516 1.00 48.53 ? 842 HOH A O 1 HETATM 4760 O O . HOH H 5 . ? 29.365 -1.425 44.424 1.00 48.03 ? 843 HOH A O 1 HETATM 4761 O O . HOH H 5 . ? 32.846 16.354 59.220 1.00 47.18 ? 844 HOH A O 1 HETATM 4762 O O . HOH H 5 . ? 35.402 16.090 58.759 1.00 51.07 ? 845 HOH A O 1 HETATM 4763 O O . HOH H 5 . ? 14.893 27.123 69.260 1.00 45.25 ? 846 HOH A O 1 HETATM 4764 O O . HOH H 5 . ? 9.950 11.082 16.065 1.00 24.23 ? 847 HOH A O 1 HETATM 4765 O O . HOH H 5 . ? -11.340 27.963 45.881 1.00 38.42 ? 848 HOH A O 1 HETATM 4766 O O . HOH H 5 . ? -1.792 17.542 54.437 1.00 36.65 ? 849 HOH A O 1 HETATM 4767 O O . HOH H 5 . ? 40.923 22.367 44.099 1.00 37.94 ? 850 HOH A O 1 HETATM 4768 O O . HOH H 5 . ? 9.308 38.766 20.374 1.00 33.99 ? 851 HOH A O 1 HETATM 4769 O O . HOH H 5 . ? 8.310 4.582 32.423 1.00 54.66 ? 852 HOH A O 1 HETATM 4770 O O . HOH H 5 . ? 23.077 40.401 43.801 1.00 49.04 ? 853 HOH A O 1 HETATM 4771 O O . HOH H 5 . ? -1.813 49.695 46.061 1.00 41.93 ? 854 HOH A O 1 HETATM 4772 O O . HOH H 5 . ? 16.974 19.881 57.938 1.00 41.37 ? 855 HOH A O 1 HETATM 4773 O O . HOH H 5 . ? 27.078 39.815 42.253 1.00 55.62 ? 856 HOH A O 1 HETATM 4774 O O . HOH H 5 . ? 4.041 9.495 51.717 1.00 59.18 ? 857 HOH A O 1 HETATM 4775 O O . HOH H 5 . ? 19.858 30.067 65.349 1.00 46.12 ? 858 HOH A O 1 HETATM 4776 O O . HOH H 5 . ? 12.427 39.934 29.617 1.00 40.36 ? 859 HOH A O 1 HETATM 4777 O O . HOH H 5 . ? 2.260 9.408 28.346 1.00 44.68 ? 860 HOH A O 1 HETATM 4778 O O . HOH H 5 . ? 22.338 6.311 3.453 1.00 39.15 ? 861 HOH A O 1 HETATM 4779 O O . HOH H 5 . ? 22.032 36.910 47.694 1.00 38.39 ? 862 HOH A O 1 HETATM 4780 O O . HOH H 5 . ? 8.196 11.222 14.029 1.00 40.25 ? 863 HOH A O 1 HETATM 4781 O O . HOH H 5 . ? 1.553 7.008 32.416 1.00 53.58 ? 864 HOH A O 1 HETATM 4782 O O . HOH H 5 . ? 49.461 20.365 34.550 1.00 56.55 ? 865 HOH A O 1 HETATM 4783 O O . HOH H 5 . ? 35.381 1.840 31.685 1.00 47.41 ? 866 HOH A O 1 HETATM 4784 O O . HOH H 5 . ? 19.155 40.931 31.249 1.00 50.46 ? 867 HOH A O 1 HETATM 4785 O O . HOH H 5 . ? -3.935 28.226 35.540 1.00 42.98 ? 868 HOH A O 1 HETATM 4786 O O . HOH H 5 . ? 22.257 38.334 41.766 1.00 36.60 ? 869 HOH A O 1 HETATM 4787 O O . HOH H 5 . ? 37.694 3.035 10.332 1.00 44.91 ? 870 HOH A O 1 HETATM 4788 O O . HOH H 5 . ? 18.867 3.000 1.376 1.00 63.80 ? 871 HOH A O 1 HETATM 4789 O O . HOH H 5 . ? 18.100 35.543 55.658 1.00 37.49 ? 872 HOH A O 1 HETATM 4790 O O . HOH H 5 . ? 3.349 3.955 31.582 1.00 54.18 ? 873 HOH A O 1 HETATM 4791 O O . HOH H 5 . ? -14.453 14.807 53.784 1.00 53.50 ? 874 HOH A O 1 HETATM 4792 O O . HOH H 5 . ? 37.326 24.928 8.097 1.00 41.39 ? 875 HOH A O 1 HETATM 4793 O O . HOH H 5 . ? -2.426 52.627 46.690 1.00 50.11 ? 876 HOH A O 1 HETATM 4794 O O . HOH H 5 . ? 28.941 17.034 3.142 1.00 52.31 ? 877 HOH A O 1 HETATM 4795 O O . HOH H 5 . ? 45.115 28.481 30.315 1.00 54.97 ? 878 HOH A O 1 HETATM 4796 O O . HOH H 5 . ? 19.990 37.465 49.924 1.00 44.55 ? 879 HOH A O 1 HETATM 4797 O O . HOH H 5 . ? 0.520 34.249 69.068 1.00 52.85 ? 880 HOH A O 1 HETATM 4798 O O . HOH H 5 . ? 27.854 14.695 56.216 1.00 49.66 ? 881 HOH A O 1 HETATM 4799 O O . HOH H 5 . ? 2.880 54.190 60.074 1.00 50.11 ? 882 HOH A O 1 HETATM 4800 O O . HOH H 5 . ? 17.053 -6.037 29.051 1.00 55.34 ? 883 HOH A O 1 HETATM 4801 O O . HOH H 5 . ? -14.931 28.846 60.310 1.00 38.55 ? 884 HOH A O 1 HETATM 4802 O O . HOH H 5 . ? 15.760 23.267 70.239 1.00 51.93 ? 885 HOH A O 1 HETATM 4803 O O . HOH H 5 . ? 15.581 33.166 53.921 1.00 48.07 ? 886 HOH A O 1 HETATM 4804 O O . HOH H 5 . ? 37.895 6.856 8.329 1.00 42.99 ? 887 HOH A O 1 HETATM 4805 O O . HOH H 5 . ? 29.706 0.147 26.473 1.00 44.21 ? 888 HOH A O 1 HETATM 4806 O O . HOH H 5 . ? 7.067 43.983 33.240 1.00 41.91 ? 889 HOH A O 1 HETATM 4807 O O . HOH H 5 . ? -1.833 35.994 70.061 1.00 51.25 ? 890 HOH A O 1 HETATM 4808 O O . HOH H 5 . ? -9.514 16.399 54.169 1.00 48.74 ? 891 HOH A O 1 HETATM 4809 O O . HOH H 5 . ? -8.952 18.964 59.509 1.00 51.35 ? 892 HOH A O 1 HETATM 4810 O O . HOH H 5 . ? -0.638 13.268 48.408 1.00 44.03 ? 893 HOH A O 1 HETATM 4811 O O . HOH H 5 . ? -0.595 16.816 24.224 1.00 47.13 ? 894 HOH A O 1 HETATM 4812 O O . HOH H 5 . ? -1.328 56.502 58.951 1.00 56.85 ? 895 HOH A O 1 HETATM 4813 O O . HOH H 5 . ? -12.717 52.395 54.680 1.00 55.61 ? 896 HOH A O 1 HETATM 4814 O O . HOH H 5 . ? 47.733 6.581 22.845 1.00 46.33 ? 897 HOH A O 1 HETATM 4815 O O . HOH H 5 . ? 38.886 8.901 44.023 1.00 39.05 ? 898 HOH A O 1 HETATM 4816 O O . HOH H 5 . ? -0.578 18.498 26.444 1.00 39.30 ? 899 HOH A O 1 HETATM 4817 O O . HOH H 5 . ? -11.497 42.942 62.490 1.00 38.48 ? 900 HOH A O 1 HETATM 4818 O O . HOH H 5 . ? 10.939 5.003 41.033 1.00 40.49 ? 901 HOH A O 1 HETATM 4819 O O . HOH H 5 . ? 28.272 26.264 3.897 1.00 51.64 ? 902 HOH A O 1 HETATM 4820 O O . HOH H 5 . ? -12.473 22.016 60.967 1.00 45.58 ? 903 HOH A O 1 HETATM 4821 O O . HOH H 5 . ? -5.139 28.806 73.772 1.00 60.38 ? 904 HOH A O 1 HETATM 4822 O O . HOH H 5 . ? 37.425 22.137 51.973 1.00 48.93 ? 905 HOH A O 1 HETATM 4823 O O . HOH H 5 . ? -4.864 13.400 34.451 1.00 48.37 ? 906 HOH A O 1 HETATM 4824 O O . HOH H 5 . ? 39.333 8.024 10.056 1.00 51.86 ? 907 HOH A O 1 HETATM 4825 O O . HOH H 5 . ? 1.045 19.124 14.241 1.00 49.12 ? 908 HOH A O 1 HETATM 4826 O O . HOH H 5 . ? 15.398 4.729 18.404 1.00 41.82 ? 909 HOH A O 1 HETATM 4827 O O . HOH H 5 . ? 33.291 27.320 59.426 1.00 52.80 ? 910 HOH A O 1 HETATM 4828 O O . HOH H 5 . ? 12.201 4.543 16.782 1.00 50.08 ? 911 HOH A O 1 HETATM 4829 O O . HOH H 5 . ? 22.334 -3.338 18.172 1.00 46.58 ? 912 HOH A O 1 HETATM 4830 O O . HOH H 5 . ? 12.550 -0.417 8.996 1.00 49.22 ? 913 HOH A O 1 HETATM 4831 O O . HOH H 5 . ? 1.167 14.861 23.632 1.00 39.43 ? 914 HOH A O 1 HETATM 4832 O O . HOH H 5 . ? 32.388 -0.104 27.676 1.00 59.63 ? 915 HOH A O 1 HETATM 4833 O O . HOH H 5 . ? 2.440 48.839 64.432 1.00 54.69 ? 916 HOH A O 1 HETATM 4834 O O . HOH H 5 . ? 32.671 2.155 4.623 1.00 55.03 ? 917 HOH A O 1 HETATM 4835 O O . HOH H 5 . ? 31.616 29.148 44.786 1.00 49.87 ? 918 HOH A O 1 HETATM 4836 O O . HOH H 5 . ? 36.675 34.522 20.066 1.00 52.24 ? 919 HOH A O 1 HETATM 4837 O O . HOH H 5 . ? 19.301 41.236 43.028 1.00 52.00 ? 920 HOH A O 1 HETATM 4838 O O . HOH H 5 . ? -2.937 33.500 69.989 1.00 46.37 ? 921 HOH A O 1 HETATM 4839 O O . HOH H 5 . ? 13.206 1.371 11.455 1.00 54.10 ? 922 HOH A O 1 HETATM 4840 O O . HOH H 5 . ? -2.903 21.157 64.772 1.00 50.70 ? 923 HOH A O 1 HETATM 4841 O O . HOH H 5 . ? 26.673 0.400 50.552 1.00 52.63 ? 924 HOH A O 1 HETATM 4842 O O . HOH H 5 . ? 0.971 30.323 71.584 1.00 52.53 ? 925 HOH A O 1 HETATM 4843 O O . HOH H 5 . ? -0.845 21.110 14.413 1.00 58.10 ? 926 HOH A O 1 HETATM 4844 O O . HOH H 5 . ? -3.769 14.058 57.148 1.00 49.21 ? 927 HOH A O 1 HETATM 4845 O O . HOH H 5 . ? 24.743 14.130 53.514 1.00 30.47 ? 928 HOH A O 1 HETATM 4846 O O . HOH H 5 . ? 48.451 22.646 23.518 1.00 36.41 ? 929 HOH A O 1 HETATM 4847 O O . HOH H 5 . ? 2.382 51.959 62.619 1.00 53.11 ? 930 HOH A O 1 HETATM 4848 O O . HOH H 5 . ? -4.498 17.341 61.362 1.00 47.38 ? 931 HOH A O 1 HETATM 4849 O O . HOH H 5 . ? 16.028 43.444 41.534 1.00 47.03 ? 932 HOH A O 1 HETATM 4850 O O . HOH H 5 . ? 39.271 6.626 48.155 1.00 50.05 ? 933 HOH A O 1 HETATM 4851 O O . HOH H 5 . ? 3.221 26.010 68.828 1.00 46.01 ? 934 HOH A O 1 HETATM 4852 O O . HOH H 5 . ? 4.966 4.596 24.896 1.00 48.72 ? 935 HOH A O 1 HETATM 4853 O O . HOH H 5 . ? 31.198 0.480 21.512 1.00 57.73 ? 936 HOH A O 1 HETATM 4854 O O . HOH H 5 . ? 23.590 23.612 68.449 1.00 56.65 ? 937 HOH A O 1 HETATM 4855 O O . HOH H 5 . ? 12.755 -1.105 37.111 1.00 50.68 ? 938 HOH A O 1 HETATM 4856 O O . HOH H 5 . ? 18.748 8.820 56.877 1.00 51.81 ? 939 HOH A O 1 HETATM 4857 O O . HOH H 5 . ? 20.759 21.236 68.333 1.00 52.40 ? 940 HOH A O 1 HETATM 4858 O O . HOH H 5 . ? 40.496 31.087 25.256 1.00 53.59 ? 941 HOH A O 1 HETATM 4859 O O . HOH H 5 . ? 27.626 34.321 36.427 1.00 41.89 ? 942 HOH A O 1 HETATM 4860 O O . HOH H 5 . ? 29.297 29.644 42.582 1.00 38.86 ? 943 HOH A O 1 HETATM 4861 O O . HOH H 5 . ? -1.988 33.116 31.807 1.00 27.27 ? 944 HOH A O 1 HETATM 4862 O O . HOH H 5 . ? -1.923 32.440 34.336 1.00 22.36 ? 945 HOH A O 1 HETATM 4863 O O . HOH H 5 . ? 19.020 23.909 37.432 1.00 15.47 ? 946 HOH A O 1 HETATM 4864 O O . HOH H 5 . ? 26.994 21.098 39.946 1.00 18.19 ? 947 HOH A O 1 HETATM 4865 O O . HOH H 5 . ? 26.636 30.343 41.599 1.00 25.11 ? 948 HOH A O 1 HETATM 4866 O O . HOH H 5 . ? -17.790 39.664 56.299 1.00 38.73 ? 949 HOH A O 1 HETATM 4867 O O . HOH H 5 . ? 13.614 37.404 13.364 1.00 27.80 ? 950 HOH A O 1 HETATM 4868 O O . HOH H 5 . ? 26.611 26.143 41.409 1.00 17.60 ? 951 HOH A O 1 HETATM 4869 O O . HOH H 5 . ? 16.156 11.794 7.710 1.00 57.71 ? 952 HOH A O 1 HETATM 4870 O O . HOH H 5 . ? 34.023 23.795 54.021 1.00 38.87 ? 953 HOH A O 1 HETATM 4871 O O . HOH H 5 . ? 10.969 11.185 11.293 1.00 38.83 ? 954 HOH A O 1 HETATM 4872 O O . HOH H 5 . ? 17.070 19.442 71.049 1.00 47.82 ? 955 HOH A O 1 HETATM 4873 O O . HOH H 5 . ? 21.937 12.654 58.492 1.00 50.04 ? 956 HOH A O 1 HETATM 4874 O O . HOH H 5 . ? 24.470 -3.654 5.274 1.00 60.51 ? 957 HOH A O 1 HETATM 4875 O O . HOH H 5 . ? 30.401 2.125 56.760 1.00 47.29 ? 958 HOH A O 1 HETATM 4876 O O . HOH H 5 . ? 38.872 29.829 16.859 1.00 48.84 ? 959 HOH A O 1 HETATM 4877 O O . HOH H 5 . ? 49.459 26.066 35.023 1.00 51.97 ? 960 HOH A O 1 HETATM 4878 O O . HOH H 5 . ? -17.142 30.807 49.464 1.00 24.44 ? 961 HOH A O 1 HETATM 4879 O O . HOH H 5 . ? 16.511 41.806 34.636 1.00 50.15 ? 962 HOH A O 1 HETATM 4880 O O . HOH H 5 . ? 4.816 13.076 59.713 1.00 46.84 ? 963 HOH A O 1 HETATM 4881 O O . HOH H 5 . ? -13.653 28.890 71.715 1.00 19.69 ? 964 HOH A O 1 HETATM 4882 O O . HOH H 5 . ? 42.727 28.992 30.616 1.00 69.44 ? 965 HOH A O 1 HETATM 4883 O O . HOH H 5 . ? 19.787 28.152 69.382 1.00 53.71 ? 966 HOH A O 1 HETATM 4884 O O . HOH H 5 . ? 22.821 34.671 30.090 1.00 25.15 ? 967 HOH A O 1 HETATM 4885 O O . HOH H 5 . ? 33.811 -0.747 38.760 1.00 45.95 ? 968 HOH A O 1 HETATM 4886 O O . HOH H 5 . ? -4.324 26.367 71.487 1.00 50.98 ? 969 HOH A O 1 HETATM 4887 O O . HOH H 5 . ? 14.027 1.530 44.067 1.00 51.51 ? 970 HOH A O 1 HETATM 4888 O O . HOH H 5 . ? 38.302 30.860 31.020 1.00 58.44 ? 971 HOH A O 1 HETATM 4889 O O . HOH H 5 . ? 7.106 39.363 18.923 1.00 36.55 ? 972 HOH A O 1 HETATM 4890 O O . HOH H 5 . ? 34.378 3.637 30.255 1.00 40.38 ? 973 HOH A O 1 HETATM 4891 O O . HOH H 5 . ? -18.972 33.030 50.470 1.00 26.99 ? 974 HOH A O 1 HETATM 4892 O O . HOH H 5 . ? -6.511 33.550 72.524 1.00 50.26 ? 975 HOH A O 1 HETATM 4893 O O . HOH H 5 . ? -6.399 41.414 37.875 1.00 35.97 ? 976 HOH A O 1 HETATM 4894 O O . HOH H 5 . ? 47.560 19.962 25.330 1.00 25.32 ? 977 HOH A O 1 HETATM 4895 O O . HOH H 5 . ? 5.959 28.293 66.615 1.00 27.10 ? 978 HOH A O 1 HETATM 4896 O O . HOH H 5 . ? 38.009 25.883 42.665 1.00 36.51 ? 979 HOH A O 1 HETATM 4897 O O . HOH H 5 . ? 32.119 28.874 42.232 1.00 40.70 ? 980 HOH A O 1 HETATM 4898 O O . HOH H 5 . ? 8.660 41.520 52.241 1.00 37.54 ? 981 HOH A O 1 HETATM 4899 O O . HOH H 5 . ? 10.194 25.498 9.825 1.00 42.67 ? 982 HOH A O 1 HETATM 4900 O O . HOH H 5 . ? -2.622 46.190 64.798 1.00 48.91 ? 983 HOH A O 1 HETATM 4901 O O . HOH H 5 . ? 8.534 25.325 69.509 1.00 43.67 ? 984 HOH A O 1 HETATM 4902 O O . HOH H 5 . ? -0.119 23.076 15.379 1.00 45.53 ? 985 HOH A O 1 HETATM 4903 O O . HOH H 5 . ? -14.496 27.845 41.189 1.00 37.71 ? 986 HOH A O 1 HETATM 4904 O O . HOH H 5 . ? 16.939 34.326 63.585 1.00 42.95 ? 987 HOH A O 1 HETATM 4905 O O . HOH H 5 . ? 28.605 28.762 59.346 1.00 47.96 ? 988 HOH A O 1 HETATM 4906 O O . HOH H 5 . ? 25.733 27.258 64.545 1.00 55.90 ? 989 HOH A O 1 HETATM 4907 O O . HOH H 5 . ? 28.020 20.932 60.465 1.00 54.24 ? 990 HOH A O 1 HETATM 4908 O O . HOH H 5 . ? 31.205 21.321 59.838 1.00 50.68 ? 991 HOH A O 1 HETATM 4909 O O . HOH H 5 . ? 1.960 32.416 69.847 1.00 39.53 ? 992 HOH A O 1 HETATM 4910 O O . HOH H 5 . ? 31.384 4.177 -3.513 1.00 42.69 ? 993 HOH A O 1 HETATM 4911 O O . HOH H 5 . ? -16.543 33.068 59.662 1.00 28.55 ? 994 HOH A O 1 HETATM 4912 O O . HOH H 5 . ? 4.806 10.280 53.553 1.00 52.36 ? 995 HOH A O 1 HETATM 4913 O O . HOH H 5 . ? 2.880 34.302 25.055 1.00 33.88 ? 996 HOH A O 1 HETATM 4914 O O . HOH H 5 . ? 41.519 24.603 18.425 1.00 24.32 ? 997 HOH A O 1 HETATM 4915 O O . HOH H 5 . ? 2.107 32.263 26.770 1.00 30.17 ? 998 HOH A O 1 HETATM 4916 O O . HOH H 5 . ? 24.991 36.515 35.848 1.00 42.98 ? 999 HOH A O 1 HETATM 4917 O O . HOH H 5 . ? 29.320 1.575 5.822 1.00 49.78 ? 1000 HOH A O 1 HETATM 4918 O O . HOH H 5 . ? -2.131 35.823 32.313 1.00 31.08 ? 1001 HOH A O 1 HETATM 4919 O O . HOH H 5 . ? -4.228 39.929 66.734 1.00 47.88 ? 1002 HOH A O 1 HETATM 4920 O O . HOH H 5 . ? 7.995 12.205 11.431 1.00 57.73 ? 1003 HOH A O 1 HETATM 4921 O O . HOH H 5 . ? 41.644 18.924 42.217 1.00 54.01 ? 1004 HOH A O 1 HETATM 4922 O O . HOH H 5 . ? 40.938 12.354 41.411 1.00 45.33 ? 1005 HOH A O 1 HETATM 4923 O O . HOH H 5 . ? 9.045 7.699 13.796 1.00 49.56 ? 1006 HOH A O 1 HETATM 4924 O O . HOH H 5 . ? -2.930 18.229 28.008 1.00 42.50 ? 1007 HOH A O 1 HETATM 4925 O O . HOH H 5 . ? -14.661 50.039 59.524 1.00 44.82 ? 1008 HOH A O 1 HETATM 4926 O O . HOH H 5 . ? 20.050 10.422 7.135 1.00 49.09 ? 1009 HOH A O 1 HETATM 4927 O O . HOH H 5 . ? 35.729 27.176 42.094 1.00 28.89 ? 1010 HOH A O 1 HETATM 4928 O O . HOH H 5 . ? 22.513 36.786 28.413 1.00 24.53 ? 1011 HOH A O 1 HETATM 4929 O O . HOH H 5 . ? 41.699 16.173 10.384 1.00 28.63 ? 1012 HOH A O 1 HETATM 4930 O O . HOH H 5 . ? 16.408 3.170 15.926 1.00 48.64 ? 1013 HOH A O 1 HETATM 4931 O O . HOH H 5 . ? 2.708 21.257 65.949 1.00 45.27 ? 1014 HOH A O 1 HETATM 4932 O O . HOH H 5 . ? 41.334 10.507 47.935 1.00 53.09 ? 1015 HOH A O 1 HETATM 4933 O O . HOH H 5 . ? -2.180 6.729 35.192 1.00 55.05 ? 1016 HOH A O 1 HETATM 4934 O O . HOH H 5 . ? 32.564 11.612 57.540 1.00 44.84 ? 1017 HOH A O 1 HETATM 4935 O O . HOH H 5 . ? 19.872 -3.441 37.234 1.00 46.95 ? 1018 HOH A O 1 HETATM 4936 O O . HOH H 5 . ? -2.408 14.063 31.073 1.00 49.66 ? 1019 HOH A O 1 HETATM 4937 O O . HOH H 5 . ? -12.837 23.000 67.765 1.00 29.94 ? 1020 HOH A O 1 HETATM 4938 O O . HOH H 5 . ? -2.365 58.720 60.267 1.00 56.43 ? 1021 HOH A O 1 HETATM 4939 O O . HOH H 5 . ? 10.482 42.886 61.147 1.00 40.06 ? 1022 HOH A O 1 HETATM 4940 O O . HOH H 5 . ? 6.830 23.266 68.622 1.00 42.82 ? 1023 HOH A O 1 HETATM 4941 O O . HOH H 5 . ? -15.626 49.281 49.605 1.00 42.15 ? 1024 HOH A O 1 HETATM 4942 O O . HOH H 5 . ? 19.822 -4.977 33.190 1.00 53.71 ? 1025 HOH A O 1 HETATM 4943 O O . HOH H 5 . ? 9.083 20.350 37.116 1.00 14.36 ? 1026 HOH A O 1 HETATM 4944 O O . HOH H 5 . ? 31.804 16.605 15.032 1.00 15.72 ? 1027 HOH A O 1 HETATM 4945 O O . HOH H 5 . ? 10.043 21.913 39.232 1.00 13.54 ? 1028 HOH A O 1 HETATM 4946 O O . HOH H 5 . ? 12.883 22.946 40.371 1.00 13.73 ? 1029 HOH A O 1 HETATM 4947 O O . HOH H 5 . ? 12.669 19.675 36.743 1.00 14.94 ? 1030 HOH A O 1 HETATM 4948 O O . HOH H 5 . ? 7.710 24.821 44.789 1.00 12.64 ? 1031 HOH A O 1 HETATM 4949 O O . HOH H 5 . ? 27.142 18.059 15.980 1.00 13.30 ? 1032 HOH A O 1 HETATM 4950 O O . HOH H 5 . ? 11.149 36.038 36.613 1.00 15.64 ? 1033 HOH A O 1 HETATM 4951 O O . HOH H 5 . ? 4.051 32.237 30.851 1.00 15.19 ? 1034 HOH A O 1 HETATM 4952 O O . HOH H 5 . ? 15.658 16.274 43.917 1.00 15.45 ? 1035 HOH A O 1 HETATM 4953 O O . HOH H 5 . ? 37.048 20.216 16.668 1.00 18.07 ? 1036 HOH A O 1 HETATM 4954 O O . HOH H 5 . ? -7.783 34.309 68.763 1.00 27.80 ? 1037 HOH A O 1 HETATM 4955 O O . HOH H 5 . ? -0.921 17.351 48.033 1.00 19.94 ? 1038 HOH A O 1 HETATM 4956 O O . HOH H 5 . ? 14.490 31.270 44.262 1.00 14.07 ? 1039 HOH A O 1 HETATM 4957 O O . HOH H 5 . ? 10.304 21.073 17.489 1.00 18.30 ? 1040 HOH A O 1 HETATM 4958 O O . HOH H 5 . ? 49.928 17.109 26.628 1.00 32.60 ? 1041 HOH A O 1 HETATM 4959 O O . HOH H 5 . ? -16.850 28.783 62.295 1.00 18.65 ? 1042 HOH A O 1 HETATM 4960 O O . HOH H 5 . ? 9.669 20.993 34.461 1.00 13.83 ? 1043 HOH A O 1 HETATM 4961 O O . HOH H 5 . ? -15.237 41.030 43.112 1.00 19.63 ? 1044 HOH A O 1 HETATM 4962 O O . HOH H 5 . ? 16.939 26.921 48.667 1.00 17.02 ? 1045 HOH A O 1 HETATM 4963 O O . HOH H 5 . ? 22.493 15.077 46.842 1.00 17.33 ? 1046 HOH A O 1 HETATM 4964 O O . HOH H 5 . ? 4.935 25.445 45.205 1.00 13.54 ? 1047 HOH A O 1 HETATM 4965 O O . HOH H 5 . ? 12.011 34.549 58.662 1.00 20.93 ? 1048 HOH A O 1 HETATM 4966 O O . HOH H 5 . ? -7.812 32.453 64.538 1.00 24.35 ? 1049 HOH A O 1 HETATM 4967 O O . HOH H 5 . ? 33.387 20.056 7.052 1.00 20.27 ? 1050 HOH A O 1 HETATM 4968 O O . HOH H 5 . ? 5.701 10.194 28.693 1.00 20.49 ? 1051 HOH A O 1 HETATM 4969 O O . HOH H 5 . ? -1.422 20.888 53.928 1.00 18.64 ? 1052 HOH A O 1 HETATM 4970 O O . HOH H 5 . ? 3.864 40.843 38.777 1.00 17.80 ? 1053 HOH A O 1 HETATM 4971 O O . HOH H 5 . ? -8.988 30.079 42.720 1.00 16.74 ? 1054 HOH A O 1 HETATM 4972 O O . HOH H 5 . ? 7.691 31.985 31.306 1.00 13.92 ? 1055 HOH A O 1 HETATM 4973 O O . HOH H 5 . ? -11.491 30.666 70.539 1.00 24.39 ? 1056 HOH A O 1 HETATM 4974 O O . HOH H 5 . ? 15.663 36.378 29.609 1.00 20.23 ? 1057 HOH A O 1 HETATM 4975 O O . HOH H 5 . ? 13.558 35.349 28.278 1.00 15.71 ? 1058 HOH A O 1 HETATM 4976 O O . HOH H 5 . ? 15.281 18.736 16.434 1.00 19.17 ? 1059 HOH A O 1 HETATM 4977 O O . HOH H 5 . ? 2.102 37.225 43.557 1.00 16.00 ? 1060 HOH A O 1 HETATM 4978 O O . HOH H 5 . ? 34.594 28.756 28.964 1.00 20.19 ? 1061 HOH A O 1 HETATM 4979 O O . HOH H 5 . ? 19.477 20.090 57.881 1.00 24.50 ? 1062 HOH A O 1 HETATM 4980 O O . HOH H 5 . ? 12.964 20.349 17.988 1.00 20.26 ? 1063 HOH A O 1 HETATM 4981 O O . HOH H 5 . ? 20.995 30.964 14.844 1.00 16.97 ? 1064 HOH A O 1 HETATM 4982 O O . HOH H 5 . ? 5.070 37.837 65.598 1.00 22.09 ? 1065 HOH A O 1 HETATM 4983 O O . HOH H 5 . ? 20.956 33.343 62.685 1.00 42.70 ? 1066 HOH A O 1 HETATM 4984 O O . HOH H 5 . ? 15.178 21.379 56.203 1.00 22.34 ? 1067 HOH A O 1 HETATM 4985 O O . HOH H 5 . ? 3.949 14.502 15.270 1.00 55.18 ? 1068 HOH A O 1 HETATM 4986 O O . HOH H 5 . ? 15.933 39.325 57.126 1.00 39.64 ? 1069 HOH A O 1 HETATM 4987 O O . HOH H 5 . ? -4.972 37.893 63.813 1.00 21.42 ? 1070 HOH A O 1 HETATM 4988 O O . HOH H 5 . ? 9.769 17.778 12.606 1.00 37.63 ? 1071 HOH A O 1 HETATM 4989 O O . HOH H 5 . ? 5.614 35.773 14.132 1.00 33.80 ? 1072 HOH A O 1 HETATM 4990 O O . HOH H 5 . ? 18.905 9.460 45.981 1.00 21.71 ? 1073 HOH A O 1 HETATM 4991 O O . HOH H 5 . ? 11.262 18.087 14.968 1.00 24.45 ? 1074 HOH A O 1 HETATM 4992 O O . HOH H 5 . ? -10.900 31.534 39.663 1.00 43.85 ? 1075 HOH A O 1 HETATM 4993 O O . HOH H 5 . ? 19.933 11.222 44.169 1.00 20.56 ? 1076 HOH A O 1 HETATM 4994 O O . HOH H 5 . ? -15.944 37.341 56.283 1.00 26.25 ? 1077 HOH A O 1 HETATM 4995 O O . HOH H 5 . ? -0.840 51.194 52.377 1.00 37.63 ? 1078 HOH A O 1 HETATM 4996 O O . HOH H 5 . ? -4.849 19.755 47.582 1.00 29.06 ? 1079 HOH A O 1 HETATM 4997 O O . HOH H 5 . ? -5.849 23.555 41.709 1.00 19.22 ? 1080 HOH A O 1 HETATM 4998 O O . HOH H 5 . ? 5.655 31.738 17.872 1.00 23.59 ? 1081 HOH A O 1 HETATM 4999 O O . HOH H 5 . ? 33.673 2.207 14.803 1.00 25.52 ? 1082 HOH A O 1 HETATM 5000 O O . HOH H 5 . ? 12.231 23.828 11.011 1.00 25.66 ? 1083 HOH A O 1 HETATM 5001 O O . HOH H 5 . ? -3.355 24.569 15.028 1.00 29.88 ? 1084 HOH A O 1 HETATM 5002 O O . HOH H 5 . ? 26.588 32.378 53.280 1.00 31.87 ? 1085 HOH A O 1 HETATM 5003 O O . HOH H 5 . ? -11.609 24.226 57.720 1.00 23.21 ? 1086 HOH A O 1 HETATM 5004 O O . HOH H 5 . ? 42.368 12.253 12.563 1.00 24.28 ? 1087 HOH A O 1 HETATM 5005 O O . HOH H 5 . ? 24.578 34.254 19.354 1.00 19.94 ? 1088 HOH A O 1 HETATM 5006 O O . HOH H 5 . ? -3.899 25.285 63.626 1.00 30.11 ? 1089 HOH A O 1 HETATM 5007 O O . HOH H 5 . ? 35.020 6.310 30.910 1.00 32.70 ? 1090 HOH A O 1 HETATM 5008 O O . HOH H 5 . ? 23.808 28.933 60.311 1.00 24.50 ? 1091 HOH A O 1 HETATM 5009 O O . HOH H 5 . ? -1.485 28.552 22.233 1.00 27.84 ? 1092 HOH A O 1 HETATM 5010 O O . HOH H 5 . ? 23.848 13.027 8.633 1.00 28.19 ? 1093 HOH A O 1 HETATM 5011 O O . HOH H 5 . ? 6.967 33.744 23.718 1.00 26.64 ? 1094 HOH A O 1 HETATM 5012 O O . HOH H 5 . ? 41.913 15.659 13.045 1.00 24.07 ? 1095 HOH A O 1 HETATM 5013 O O . HOH H 5 . ? 27.204 29.786 53.119 1.00 24.18 ? 1096 HOH A O 1 HETATM 5014 O O . HOH H 5 . ? -10.572 46.094 58.866 1.00 20.99 ? 1097 HOH A O 1 HETATM 5015 O O . HOH H 5 . ? 34.390 13.053 44.233 1.00 25.80 ? 1098 HOH A O 1 HETATM 5016 O O . HOH H 5 . ? 33.933 22.131 8.682 1.00 25.41 ? 1099 HOH A O 1 HETATM 5017 O O . HOH H 5 . ? 1.441 38.196 33.407 1.00 21.42 ? 1100 HOH A O 1 HETATM 5018 O O . HOH H 5 . ? 17.555 30.624 63.730 1.00 28.63 ? 1101 HOH A O 1 HETATM 5019 O O . HOH H 5 . ? -16.239 33.487 57.130 1.00 25.51 ? 1102 HOH A O 1 HETATM 5020 O O . HOH H 5 . ? 12.135 38.598 58.864 1.00 27.08 ? 1103 HOH A O 1 HETATM 5021 O O . HOH H 5 . ? 8.463 4.527 35.307 1.00 28.97 ? 1104 HOH A O 1 HETATM 5022 O O . HOH H 5 . ? 10.600 26.135 12.530 1.00 34.54 ? 1105 HOH A O 1 HETATM 5023 O O . HOH H 5 . ? -1.621 39.245 65.074 1.00 26.65 ? 1106 HOH A O 1 HETATM 5024 O O . HOH H 5 . ? 12.557 34.389 13.951 1.00 24.61 ? 1107 HOH A O 1 HETATM 5025 O O . HOH H 5 . ? -6.628 48.336 45.602 1.00 28.01 ? 1108 HOH A O 1 HETATM 5026 O O . HOH H 5 . ? 9.421 43.113 18.508 1.00 25.71 ? 1109 HOH A O 1 HETATM 5027 O O . HOH H 5 . ? -7.865 38.408 37.781 1.00 29.33 ? 1110 HOH A O 1 HETATM 5028 O O . HOH H 5 . ? 0.148 45.611 64.878 1.00 48.58 ? 1111 HOH A O 1 HETATM 5029 O O . HOH H 5 . ? -6.349 27.733 35.027 1.00 24.54 ? 1112 HOH A O 1 HETATM 5030 O O . HOH H 5 . ? -5.432 34.001 70.450 1.00 35.49 ? 1113 HOH A O 1 HETATM 5031 O O . HOH H 5 . ? 6.538 44.694 36.761 1.00 32.06 ? 1114 HOH A O 1 HETATM 5032 O O . HOH H 5 . ? 32.343 2.799 24.286 1.00 34.05 ? 1115 HOH A O 1 HETATM 5033 O O . HOH H 5 . ? 21.270 -0.859 18.469 1.00 28.06 ? 1116 HOH A O 1 HETATM 5034 O O . HOH H 5 . ? -7.960 36.955 67.919 1.00 40.74 ? 1117 HOH A O 1 HETATM 5035 O O . HOH H 5 . ? 14.539 27.184 29.961 1.00 12.34 ? 1118 HOH A O 1 HETATM 5036 O O . HOH H 5 . ? 15.333 31.477 10.063 1.00 33.57 ? 1119 HOH A O 1 HETATM 5037 O O . HOH H 5 . ? 7.947 11.729 20.168 1.00 28.36 ? 1120 HOH A O 1 HETATM 5038 O O . HOH H 5 . ? 37.235 5.140 28.009 1.00 25.54 ? 1121 HOH A O 1 HETATM 5039 O O . HOH H 5 . ? 23.303 13.657 3.613 1.00 40.63 ? 1122 HOH A O 1 HETATM 5040 O O . HOH H 5 . ? 20.773 -4.675 9.812 1.00 54.10 ? 1123 HOH A O 1 HETATM 5041 O O . HOH H 5 . ? 11.710 35.037 39.168 1.00 13.42 ? 1124 HOH A O 1 HETATM 5042 O O . HOH H 5 . ? 4.630 20.155 11.182 1.00 36.90 ? 1125 HOH A O 1 HETATM 5043 O O . HOH H 5 . ? 9.021 8.787 52.172 1.00 53.23 ? 1126 HOH A O 1 HETATM 5044 O O . HOH H 5 . ? 17.154 35.833 53.672 1.00 38.19 ? 1127 HOH A O 1 HETATM 5045 O O . HOH H 5 . ? 32.915 27.671 7.711 1.00 31.03 ? 1128 HOH A O 1 HETATM 5046 O O . HOH H 5 . ? 29.738 9.084 57.238 1.00 34.54 ? 1129 HOH A O 1 HETATM 5047 O O . HOH H 5 . ? 15.020 19.630 38.287 1.00 14.43 ? 1130 HOH A O 1 HETATM 5048 O O . HOH H 5 . ? 35.630 9.359 6.494 1.00 26.21 ? 1131 HOH A O 1 HETATM 5049 O O . HOH H 5 . ? 24.272 36.991 40.150 1.00 32.74 ? 1132 HOH A O 1 HETATM 5050 O O . HOH H 5 . ? -15.980 31.410 61.272 1.00 34.41 ? 1133 HOH A O 1 HETATM 5051 O O . HOH H 5 . ? 21.895 15.082 59.524 1.00 36.54 ? 1134 HOH A O 1 HETATM 5052 O O . HOH H 5 . ? 2.748 38.323 66.916 1.00 31.50 ? 1135 HOH A O 1 HETATM 5053 O O . HOH H 5 . ? 34.612 21.174 39.622 1.00 26.38 ? 1136 HOH A O 1 HETATM 5054 O O . HOH H 5 . ? 12.546 11.551 15.234 1.00 26.29 ? 1137 HOH A O 1 HETATM 5055 O O . HOH H 5 . ? 39.951 5.246 16.688 1.00 31.89 ? 1138 HOH A O 1 HETATM 5056 O O . HOH H 5 . ? 1.719 50.189 50.673 1.00 32.02 ? 1139 HOH A O 1 HETATM 5057 O O . HOH H 5 . ? 9.540 41.328 22.089 1.00 54.83 ? 1140 HOH A O 1 HETATM 5058 O O . HOH H 5 . ? -23.265 36.039 43.375 1.00 44.60 ? 1141 HOH A O 1 HETATM 5059 O O . HOH H 5 . ? -0.540 52.248 55.049 1.00 29.41 ? 1142 HOH A O 1 HETATM 5060 O O . HOH H 5 . ? 34.238 4.461 54.815 1.00 56.13 ? 1143 HOH A O 1 HETATM 5061 O O . HOH H 5 . ? -8.012 51.905 55.728 1.00 38.83 ? 1144 HOH A O 1 HETATM 5062 O O . HOH H 5 . ? 18.703 39.281 27.293 1.00 28.51 ? 1145 HOH A O 1 HETATM 5063 O O . HOH H 5 . ? 34.245 5.993 52.930 1.00 36.18 ? 1146 HOH A O 1 HETATM 5064 O O . HOH H 5 . ? 18.622 9.589 14.806 1.00 17.21 ? 1147 HOH A O 1 HETATM 5065 O O . HOH H 5 . ? -2.285 21.429 49.477 1.00 15.66 ? 1148 HOH A O 1 HETATM 5066 O O . HOH H 5 . ? 2.030 8.881 31.034 1.00 47.68 ? 1149 HOH A O 1 HETATM 5067 O O . HOH H 5 . ? -10.618 19.731 58.129 1.00 47.11 ? 1150 HOH A O 1 HETATM 5068 O O . HOH H 5 . ? -10.437 22.855 59.627 1.00 30.54 ? 1151 HOH A O 1 HETATM 5069 O O . HOH H 5 . ? 36.802 27.550 30.168 1.00 34.75 ? 1152 HOH A O 1 HETATM 5070 O O . HOH H 5 . ? 13.180 2.057 50.364 1.00 61.94 ? 1153 HOH A O 1 HETATM 5071 O O . HOH H 5 . ? 49.176 15.453 36.429 1.00 49.26 ? 1154 HOH A O 1 HETATM 5072 O O . HOH H 5 . ? 6.866 25.350 30.274 1.00 13.62 ? 1155 HOH A O 1 HETATM 5073 O O . HOH H 5 . ? 29.458 29.692 54.673 1.00 29.22 ? 1156 HOH A O 1 HETATM 5074 O O . HOH H 5 . ? 6.971 28.225 51.649 1.00 15.59 ? 1157 HOH A O 1 HETATM 5075 O O . HOH H 5 . ? 8.284 28.417 40.375 1.00 12.70 ? 1158 HOH A O 1 HETATM 5076 O O . HOH H 5 . ? 2.355 27.396 38.466 1.00 13.26 ? 1159 HOH A O 1 HETATM 5077 O O . HOH H 5 . ? 33.927 18.786 40.705 1.00 18.45 ? 1160 HOH A O 1 HETATM 5078 O O . HOH H 5 . ? 32.106 16.562 9.701 1.00 16.73 ? 1161 HOH A O 1 HETATM 5079 O O . HOH H 5 . ? 10.863 18.449 38.429 1.00 13.39 ? 1162 HOH A O 1 HETATM 5080 O O . HOH H 5 . ? 13.032 32.430 46.270 1.00 14.65 ? 1163 HOH A O 1 HETATM 5081 O O . HOH H 5 . ? 12.020 19.668 34.031 1.00 15.47 ? 1164 HOH A O 1 HETATM 5082 O O . HOH H 5 . ? 11.573 28.220 62.286 1.00 21.96 ? 1165 HOH A O 1 HETATM 5083 O O . HOH H 5 . ? 21.882 33.648 19.241 1.00 15.86 ? 1166 HOH A O 1 HETATM 5084 O O . HOH H 5 . ? 11.268 33.898 25.093 1.00 14.38 ? 1167 HOH A O 1 HETATM 5085 O O . HOH H 5 . ? 29.124 20.809 13.842 1.00 16.81 ? 1168 HOH A O 1 HETATM 5086 O O . HOH H 5 . ? 30.964 16.838 12.248 1.00 17.03 ? 1169 HOH A O 1 HETATM 5087 O O . HOH H 5 . ? 35.548 24.514 30.552 1.00 19.66 ? 1170 HOH A O 1 HETATM 5088 O O . HOH H 5 . ? 15.674 30.844 33.741 1.00 16.69 ? 1171 HOH A O 1 HETATM 5089 O O . HOH H 5 . ? 19.335 27.393 30.895 1.00 14.26 ? 1172 HOH A O 1 HETATM 5090 O O . HOH H 5 . ? 20.328 36.479 36.602 1.00 18.32 ? 1173 HOH A O 1 HETATM 5091 O O . HOH H 5 . ? -9.335 24.374 51.338 1.00 21.67 ? 1174 HOH A O 1 HETATM 5092 O O . HOH H 5 . ? 20.273 35.871 33.688 1.00 18.68 ? 1175 HOH A O 1 HETATM 5093 O O . HOH H 5 . ? 12.600 7.782 29.852 1.00 18.21 ? 1176 HOH A O 1 HETATM 5094 O O . HOH H 5 . ? 7.172 17.537 16.364 1.00 22.97 ? 1177 HOH A O 1 HETATM 5095 O O . HOH H 5 . ? 15.530 22.038 39.497 1.00 15.44 ? 1178 HOH A O 1 HETATM 5096 O O . HOH H 5 . ? 28.577 18.307 12.531 1.00 16.28 ? 1179 HOH A O 1 HETATM 5097 O O . HOH H 5 . ? 11.134 34.286 45.326 1.00 15.61 ? 1180 HOH A O 1 HETATM 5098 O O . HOH H 5 . ? 4.958 14.970 26.238 1.00 25.34 ? 1181 HOH A O 1 HETATM 5099 O O . HOH H 5 . ? 19.437 27.168 42.723 1.00 18.65 ? 1182 HOH A O 1 HETATM 5100 O O . HOH H 5 . ? 2.952 42.516 46.025 1.00 19.28 ? 1183 HOH A O 1 HETATM 5101 O O . HOH H 5 . ? 22.192 14.717 42.620 1.00 18.15 ? 1184 HOH A O 1 HETATM 5102 O O . HOH H 5 . ? 34.106 22.821 41.786 1.00 19.58 ? 1185 HOH A O 1 HETATM 5103 O O . HOH H 5 . ? 9.620 18.389 17.236 1.00 19.91 ? 1186 HOH A O 1 HETATM 5104 O O . HOH H 5 . ? -8.951 32.308 40.943 1.00 19.99 ? 1187 HOH A O 1 HETATM 5105 O O . HOH H 5 . ? 13.373 35.567 25.575 1.00 17.43 ? 1188 HOH A O 1 HETATM 5106 O O . HOH H 5 . ? -3.436 30.743 37.672 1.00 16.82 ? 1189 HOH A O 1 HETATM 5107 O O . HOH H 5 . ? 17.634 10.658 52.390 1.00 22.66 ? 1190 HOH A O 1 HETATM 5108 O O . HOH H 5 . ? 42.100 25.000 35.762 1.00 22.28 ? 1191 HOH A O 1 HETATM 5109 O O . HOH H 5 . ? 5.756 42.657 52.631 1.00 18.55 ? 1192 HOH A O 1 HETATM 5110 O O . HOH H 5 . ? 33.769 22.666 32.038 1.00 17.00 ? 1193 HOH A O 1 HETATM 5111 O O . HOH H 5 . ? 24.492 20.813 49.691 1.00 19.44 ? 1194 HOH A O 1 HETATM 5112 O O . HOH H 5 . ? 11.839 37.582 28.054 1.00 18.74 ? 1195 HOH A O 1 HETATM 5113 O O . HOH H 5 . ? 14.343 20.414 49.295 1.00 19.45 ? 1196 HOH A O 1 HETATM 5114 O O . HOH H 5 . ? -3.584 46.554 62.383 1.00 29.92 ? 1197 HOH A O 1 HETATM 5115 O O . HOH H 5 . ? 9.233 34.479 61.028 1.00 20.46 ? 1198 HOH A O 1 HETATM 5116 O O . HOH H 5 . ? -13.365 33.316 37.551 1.00 18.67 ? 1199 HOH A O 1 HETATM 5117 O O . HOH H 5 . ? -15.283 29.160 50.973 1.00 29.07 ? 1200 HOH A O 1 HETATM 5118 O O . HOH H 5 . ? 18.384 32.838 62.071 1.00 25.31 ? 1201 HOH A O 1 HETATM 5119 O O . HOH H 5 . ? 24.263 19.397 53.202 1.00 21.39 ? 1202 HOH A O 1 HETATM 5120 O O . HOH H 5 . ? 33.588 25.284 42.855 1.00 25.61 ? 1203 HOH A O 1 HETATM 5121 O O . HOH H 5 . ? 20.165 5.472 31.652 1.00 21.87 ? 1204 HOH A O 1 HETATM 5122 O O . HOH H 5 . ? 18.208 37.514 29.350 1.00 21.23 ? 1205 HOH A O 1 HETATM 5123 O O . HOH H 5 . ? 25.303 27.765 53.144 1.00 20.84 ? 1206 HOH A O 1 HETATM 5124 O O . HOH H 5 . ? 25.899 23.726 42.366 1.00 18.09 ? 1207 HOH A O 1 HETATM 5125 O O . HOH H 5 . ? 25.502 20.402 56.563 1.00 27.23 ? 1208 HOH A O 1 HETATM 5126 O O . HOH H 5 . ? 35.057 29.012 36.760 1.00 32.54 ? 1209 HOH A O 1 HETATM 5127 O O . HOH H 5 . ? 35.817 18.933 6.451 1.00 23.90 ? 1210 HOH A O 1 HETATM 5128 O O . HOH H 5 . ? -12.520 48.794 60.338 1.00 29.63 ? 1211 HOH A O 1 HETATM 5129 O O . HOH H 5 . ? 17.068 22.546 15.068 1.00 20.51 ? 1212 HOH A O 1 HETATM 5130 O O . HOH H 5 . ? 28.131 30.217 50.461 1.00 22.76 ? 1213 HOH A O 1 HETATM 5131 O O . HOH H 5 . ? -15.998 43.706 55.138 1.00 19.35 ? 1214 HOH A O 1 HETATM 5132 O O . HOH H 5 . ? 9.413 39.155 52.798 1.00 25.47 ? 1215 HOH A O 1 HETATM 5133 O O . HOH H 5 . ? 27.271 21.375 43.126 1.00 19.34 ? 1216 HOH A O 1 HETATM 5134 O O . HOH H 5 . ? 13.532 13.070 17.261 1.00 24.27 ? 1217 HOH A O 1 HETATM 5135 O O . HOH H 5 . ? -7.495 17.213 52.335 1.00 32.59 ? 1218 HOH A O 1 HETATM 5136 O O . HOH H 5 . ? 26.730 21.701 45.818 1.00 18.71 ? 1219 HOH A O 1 HETATM 5137 O O . HOH H 5 . ? -12.706 44.761 43.861 1.00 23.24 ? 1220 HOH A O 1 HETATM 5138 O O . HOH H 5 . ? 46.826 21.231 19.917 1.00 21.83 ? 1221 HOH A O 1 HETATM 5139 O O . HOH H 5 . ? -13.558 31.412 60.314 1.00 24.75 ? 1222 HOH A O 1 HETATM 5140 O O . HOH H 5 . ? 23.056 13.813 55.702 1.00 26.56 ? 1223 HOH A O 1 HETATM 5141 O O . HOH H 5 . ? -13.322 31.760 57.485 1.00 18.10 ? 1224 HOH A O 1 HETATM 5142 O O . HOH H 5 . ? 0.857 15.298 50.065 1.00 23.81 ? 1225 HOH A O 1 HETATM 5143 O O . HOH H 5 . ? 23.083 -0.493 30.192 1.00 26.67 ? 1226 HOH A O 1 HETATM 5144 O O . HOH H 5 . ? 2.399 26.316 16.088 1.00 24.05 ? 1227 HOH A O 1 HETATM 5145 O O . HOH H 5 . ? 14.920 21.623 16.640 1.00 20.90 ? 1228 HOH A O 1 HETATM 5146 O O . HOH H 5 . ? 16.187 38.480 43.722 1.00 29.98 ? 1229 HOH A O 1 HETATM 5147 O O . HOH H 5 . ? 22.280 20.851 51.474 1.00 25.52 ? 1230 HOH A O 1 HETATM 5148 O O . HOH H 5 . ? -12.988 40.625 41.707 1.00 19.51 ? 1231 HOH A O 1 HETATM 5149 O O . HOH H 5 . ? 29.374 2.735 25.462 1.00 29.41 ? 1232 HOH A O 1 HETATM 5150 O O . HOH H 5 . ? 34.179 21.238 45.214 1.00 25.36 ? 1233 HOH A O 1 HETATM 5151 O O . HOH H 5 . ? 5.469 7.962 27.172 1.00 24.58 ? 1234 HOH A O 1 HETATM 5152 O O . HOH H 5 . ? 42.513 26.501 16.703 1.00 42.20 ? 1235 HOH A O 1 HETATM 5153 O O . HOH H 5 . ? 15.464 36.597 50.067 1.00 24.36 ? 1236 HOH A O 1 HETATM 5154 O O . HOH H 5 . ? 13.679 17.800 11.286 1.00 31.04 ? 1237 HOH A O 1 HETATM 5155 O O . HOH H 5 . ? -20.214 41.074 49.350 1.00 28.04 ? 1238 HOH A O 1 HETATM 5156 O O . HOH H 5 . ? -18.087 36.936 54.461 1.00 21.65 ? 1239 HOH A O 1 HETATM 5157 O O . HOH H 5 . ? 6.705 43.203 45.163 1.00 19.75 ? 1240 HOH A O 1 HETATM 5158 O O . HOH H 5 . ? -4.737 42.807 39.832 1.00 28.42 ? 1241 HOH A O 1 HETATM 5159 O O . HOH H 5 . ? 13.958 23.400 50.311 1.00 25.99 ? 1242 HOH A O 1 HETATM 5160 O O . HOH H 5 . ? 14.913 15.405 17.201 1.00 19.22 ? 1243 HOH A O 1 HETATM 5161 O O . HOH H 5 . ? 17.301 18.408 56.044 1.00 40.37 ? 1244 HOH A O 1 HETATM 5162 O O . HOH H 5 . ? 29.588 32.616 10.611 1.00 30.16 ? 1245 HOH A O 1 HETATM 5163 O O . HOH H 5 . ? 22.998 22.496 6.077 1.00 27.09 ? 1246 HOH A O 1 HETATM 5164 O O . HOH H 5 . ? 5.408 14.499 23.666 1.00 27.48 ? 1247 HOH A O 1 HETATM 5165 O O . HOH H 5 . ? -2.349 15.006 53.186 1.00 35.60 ? 1248 HOH A O 1 HETATM 5166 O O . HOH H 5 . ? 21.588 1.023 21.058 1.00 31.52 ? 1249 HOH A O 1 HETATM 5167 O O . HOH H 5 . ? 16.173 11.942 56.330 1.00 38.21 ? 1250 HOH A O 1 HETATM 5168 O O . HOH H 5 . ? 45.537 2.812 33.506 1.00 32.68 ? 1251 HOH A O 1 HETATM 5169 O O . HOH H 5 . ? 46.693 23.891 23.247 1.00 27.35 ? 1252 HOH A O 1 HETATM 5170 O O . HOH H 5 . ? 36.627 3.015 23.423 1.00 27.20 ? 1253 HOH A O 1 HETATM 5171 O O . HOH H 5 . ? -17.284 47.408 50.619 1.00 42.81 ? 1254 HOH A O 1 HETATM 5172 O O . HOH H 5 . ? 24.670 18.093 55.501 1.00 28.98 ? 1255 HOH A O 1 HETATM 5173 O O . HOH H 5 . ? 33.038 3.240 9.675 1.00 25.92 ? 1256 HOH A O 1 HETATM 5174 O O . HOH H 5 . ? 10.649 38.956 30.082 1.00 25.80 ? 1257 HOH A O 1 HETATM 5175 O O . HOH H 5 . ? 28.307 -0.532 11.636 1.00 26.17 ? 1258 HOH A O 1 HETATM 5176 O O . HOH H 5 . ? 40.105 16.532 43.408 1.00 28.47 ? 1259 HOH A O 1 HETATM 5177 O O . HOH H 5 . ? 32.989 32.875 18.934 1.00 24.17 ? 1260 HOH A O 1 HETATM 5178 O O . HOH H 5 . ? 46.521 9.261 22.411 1.00 25.59 ? 1261 HOH A O 1 HETATM 5179 O O . HOH H 5 . ? 15.331 36.432 17.614 1.00 26.88 ? 1262 HOH A O 1 HETATM 5180 O O . HOH H 5 . ? -9.563 50.632 52.143 1.00 45.74 ? 1263 HOH A O 1 HETATM 5181 O O . HOH H 5 . ? 32.196 25.980 47.614 1.00 25.69 ? 1264 HOH A O 1 HETATM 5182 O O . HOH H 5 . ? -11.684 17.782 50.233 1.00 45.64 ? 1265 HOH A O 1 HETATM 5183 O O . HOH H 5 . ? 1.011 16.717 30.639 1.00 21.85 ? 1266 HOH A O 1 HETATM 5184 O O . HOH H 5 . ? -14.168 39.821 59.943 1.00 27.96 ? 1267 HOH A O 1 HETATM 5185 O O . HOH H 5 . ? 7.969 35.496 15.777 1.00 23.39 ? 1268 HOH A O 1 HETATM 5186 O O . HOH H 5 . ? 17.877 2.854 43.938 1.00 29.02 ? 1269 HOH A O 1 HETATM 5187 O O . HOH H 5 . ? -0.359 52.610 62.004 1.00 30.26 ? 1270 HOH A O 1 HETATM 5188 O O . HOH H 5 . ? -7.215 31.843 31.181 1.00 38.94 ? 1271 HOH A O 1 HETATM 5189 O O . HOH H 5 . ? -13.543 28.259 57.364 1.00 25.11 ? 1272 HOH A O 1 HETATM 5190 O O . HOH H 5 . ? 25.177 32.572 42.368 1.00 24.46 ? 1273 HOH A O 1 HETATM 5191 O O . HOH H 5 . ? 15.274 7.457 14.248 1.00 23.98 ? 1274 HOH A O 1 HETATM 5192 O O . HOH H 5 . ? 35.308 32.082 22.780 1.00 29.12 ? 1275 HOH A O 1 HETATM 5193 O O . HOH H 5 . ? -5.838 18.955 59.862 1.00 31.44 ? 1276 HOH A O 1 HETATM 5194 O O . HOH H 5 . ? 35.351 29.679 12.812 1.00 30.50 ? 1277 HOH A O 1 HETATM 5195 O O . HOH H 5 . ? 29.343 17.399 54.284 1.00 29.75 ? 1278 HOH A O 1 HETATM 5196 O O . HOH H 5 . ? 20.167 36.796 43.099 1.00 25.67 ? 1279 HOH A O 1 HETATM 5197 O O . HOH H 5 . ? -1.526 15.397 55.980 1.00 35.10 ? 1280 HOH A O 1 HETATM 5198 O O . HOH H 5 . ? -11.647 29.931 43.500 1.00 24.82 ? 1281 HOH A O 1 HETATM 5199 O O . HOH H 5 . ? 0.579 49.116 47.469 1.00 25.09 ? 1282 HOH A O 1 HETATM 5200 O O . HOH H 5 . ? 3.454 11.570 26.643 1.00 33.52 ? 1283 HOH A O 1 HETATM 5201 O O . HOH H 5 . ? -6.582 58.757 62.072 1.00 28.23 ? 1284 HOH A O 1 HETATM 5202 O O . HOH H 5 . ? 32.357 2.712 28.698 1.00 29.72 ? 1285 HOH A O 1 HETATM 5203 O O . HOH H 5 . ? 0.397 16.604 60.128 1.00 31.15 ? 1286 HOH A O 1 HETATM 5204 O O . HOH H 5 . ? 18.921 33.883 50.234 1.00 36.66 ? 1287 HOH A O 1 HETATM 5205 O O . HOH H 5 . ? 7.655 5.975 24.693 1.00 29.22 ? 1288 HOH A O 1 HETATM 5206 O O . HOH H 5 . ? 3.799 30.153 20.901 1.00 27.65 ? 1289 HOH A O 1 HETATM 5207 O O . HOH H 5 . ? -7.325 52.600 63.354 1.00 36.77 ? 1290 HOH A O 1 HETATM 5208 O O . HOH H 5 . ? 33.791 7.799 5.151 1.00 24.13 ? 1291 HOH A O 1 HETATM 5209 O O . HOH H 5 . ? 27.290 33.747 29.546 1.00 30.41 ? 1292 HOH A O 1 HETATM 5210 O O . HOH H 5 . ? -7.585 22.754 59.076 1.00 26.24 ? 1293 HOH A O 1 HETATM 5211 O O . HOH H 5 . ? 19.727 2.944 21.720 1.00 27.56 ? 1294 HOH A O 1 HETATM 5212 O O . HOH H 5 . ? 36.200 3.388 15.139 1.00 28.49 ? 1295 HOH A O 1 HETATM 5213 O O . HOH H 5 . ? 6.160 10.542 46.608 1.00 26.22 ? 1296 HOH A O 1 HETATM 5214 O O . HOH H 5 . ? 34.087 25.284 45.642 1.00 26.67 ? 1297 HOH A O 1 HETATM 5215 O O . HOH H 5 . ? 13.613 8.181 19.003 1.00 28.06 ? 1298 HOH A O 1 HETATM 5216 O O . HOH H 5 . ? 4.361 45.967 62.008 1.00 24.12 ? 1299 HOH A O 1 HETATM 5217 O O . HOH H 5 . ? 28.523 1.152 18.927 1.00 33.70 ? 1300 HOH A O 1 HETATM 5218 O O . HOH H 5 . ? 8.415 37.766 16.456 1.00 48.89 ? 1301 HOH A O 1 HETATM 5219 O O . HOH H 5 . ? 2.152 14.590 26.359 1.00 34.44 ? 1302 HOH A O 1 HETATM 5220 O O . HOH H 5 . ? -5.106 14.514 52.858 1.00 37.02 ? 1303 HOH A O 1 HETATM 5221 O O . HOH H 5 . ? 29.108 1.510 30.757 1.00 28.92 ? 1304 HOH A O 1 HETATM 5222 O O . HOH H 5 . ? 23.472 31.248 13.528 1.00 25.05 ? 1305 HOH A O 1 HETATM 5223 O O . HOH H 5 . ? -23.202 38.894 43.825 1.00 35.89 ? 1306 HOH A O 1 HETATM 5224 O O . HOH H 5 . ? 27.840 2.608 4.316 1.00 29.18 ? 1307 HOH A O 1 HETATM 5225 O O . HOH H 5 . ? 7.517 6.868 41.545 1.00 27.48 ? 1308 HOH A O 1 HETATM 5226 O O . HOH H 5 . ? 18.212 10.937 58.269 1.00 36.70 ? 1309 HOH A O 1 HETATM 5227 O O . HOH H 5 . ? 17.613 -3.871 33.235 1.00 35.24 ? 1310 HOH A O 1 HETATM 5228 O O . HOH H 5 . ? 38.097 19.261 46.541 1.00 31.53 ? 1311 HOH A O 1 HETATM 5229 O O . HOH H 5 . ? 11.236 36.535 60.506 1.00 25.95 ? 1312 HOH A O 1 HETATM 5230 O O . HOH H 5 . ? 39.707 3.238 20.349 1.00 36.99 ? 1313 HOH A O 1 HETATM 5231 O O . HOH H 5 . ? 24.140 -2.649 29.283 1.00 39.50 ? 1314 HOH A O 1 HETATM 5232 O O . HOH H 5 . ? 18.227 38.483 37.466 1.00 34.55 ? 1315 HOH A O 1 HETATM 5233 O O . HOH H 5 . ? -4.264 29.567 34.034 1.00 25.00 ? 1316 HOH A O 1 HETATM 5234 O O . HOH H 5 . ? 36.591 8.899 45.485 1.00 28.03 ? 1317 HOH A O 1 HETATM 5235 O O . HOH H 5 . ? 13.254 39.351 33.639 1.00 26.52 ? 1318 HOH A O 1 HETATM 5236 O O . HOH H 5 . ? 37.493 15.800 53.135 1.00 35.93 ? 1319 HOH A O 1 HETATM 5237 O O . HOH H 5 . ? 4.019 44.549 44.511 1.00 26.70 ? 1320 HOH A O 1 HETATM 5238 O O . HOH H 5 . ? 10.394 26.872 68.580 1.00 31.53 ? 1321 HOH A O 1 HETATM 5239 O O . HOH H 5 . ? -10.772 44.726 61.298 1.00 26.60 ? 1322 HOH A O 1 HETATM 5240 O O . HOH H 5 . ? 2.077 49.679 61.568 1.00 32.16 ? 1323 HOH A O 1 HETATM 5241 O O . HOH H 5 . ? -12.810 19.644 45.058 1.00 36.60 ? 1324 HOH A O 1 HETATM 5242 O O . HOH H 5 . ? 5.110 30.880 67.060 1.00 25.47 ? 1325 HOH A O 1 HETATM 5243 O O . HOH H 5 . ? -17.305 44.485 44.111 1.00 33.29 ? 1326 HOH A O 1 HETATM 5244 O O . HOH H 5 . ? 18.810 8.984 23.894 1.00 23.08 ? 1327 HOH A O 1 HETATM 5245 O O . HOH H 5 . ? 40.021 9.526 14.500 1.00 29.59 ? 1328 HOH A O 1 HETATM 5246 O O . HOH H 5 . ? 18.666 4.034 14.317 1.00 32.99 ? 1329 HOH A O 1 HETATM 5247 O O . HOH H 5 . ? 36.778 28.883 14.957 1.00 26.99 ? 1330 HOH A O 1 HETATM 5248 O O . HOH H 5 . ? 1.238 29.573 66.363 1.00 38.57 ? 1331 HOH A O 1 HETATM 5249 O O . HOH H 5 . ? 31.271 3.204 54.433 1.00 37.65 ? 1332 HOH A O 1 HETATM 5250 O O . HOH H 5 . ? -10.486 26.202 29.212 1.00 22.19 ? 1333 HOH A O 1 HETATM 5251 O O . HOH H 5 . ? -6.275 22.941 37.251 1.00 29.04 ? 1334 HOH A O 1 HETATM 5252 O O . HOH H 5 . ? 42.801 13.433 9.976 1.00 35.81 ? 1335 HOH A O 1 HETATM 5253 O O . HOH H 5 . ? 29.903 15.867 46.049 1.00 28.20 ? 1336 HOH A O 1 HETATM 5254 O O . HOH H 5 . ? 36.947 2.886 17.765 1.00 31.13 ? 1337 HOH A O 1 HETATM 5255 O O . HOH H 5 . ? -18.051 44.590 56.499 1.00 30.23 ? 1338 HOH A O 1 HETATM 5256 O O . HOH H 5 . ? 20.316 20.311 6.240 1.00 37.98 ? 1339 HOH A O 1 HETATM 5257 O O . HOH H 5 . ? 3.907 7.897 37.273 1.00 29.96 ? 1340 HOH A O 1 HETATM 5258 O O . HOH H 5 . ? 23.500 16.225 57.061 1.00 28.72 ? 1341 HOH A O 1 HETATM 5259 O O . HOH H 5 . ? -3.503 13.485 48.565 1.00 52.36 ? 1342 HOH A O 1 HETATM 5260 O O . HOH H 5 . ? 18.061 2.662 23.958 1.00 29.98 ? 1343 HOH A O 1 HETATM 5261 O O . HOH H 5 . ? 35.980 8.850 49.983 1.00 30.35 ? 1344 HOH A O 1 HETATM 5262 O O . HOH H 5 . ? 22.814 28.962 9.494 1.00 35.40 ? 1345 HOH A O 1 HETATM 5263 O O . HOH H 5 . ? 28.781 33.185 27.036 1.00 26.76 ? 1346 HOH A O 1 HETATM 5264 O O . HOH H 5 . ? -5.324 52.348 65.044 1.00 36.26 ? 1347 HOH A O 1 HETATM 5265 O O . HOH H 5 . ? 3.861 34.441 20.333 1.00 30.05 ? 1348 HOH A O 1 HETATM 5266 O O . HOH H 5 . ? 24.673 33.741 54.757 1.00 28.65 ? 1349 HOH A O 1 HETATM 5267 O O . HOH H 5 . ? -10.275 18.546 47.735 1.00 39.77 ? 1350 HOH A O 1 HETATM 5268 O O . HOH H 5 . ? -9.662 52.243 54.101 1.00 46.46 ? 1351 HOH A O 1 HETATM 5269 O O . HOH H 5 . ? 40.076 4.469 27.605 1.00 27.31 ? 1352 HOH A O 1 HETATM 5270 O O . HOH H 5 . ? 31.049 2.606 18.824 1.00 29.00 ? 1353 HOH A O 1 HETATM 5271 O O . HOH H 5 . ? 25.785 -1.062 25.569 1.00 47.23 ? 1354 HOH A O 1 HETATM 5272 O O . HOH H 5 . ? 40.949 12.247 36.832 1.00 33.16 ? 1355 HOH A O 1 HETATM 5273 O O . HOH H 5 . ? -1.179 37.129 67.443 1.00 34.30 ? 1356 HOH A O 1 HETATM 5274 O O . HOH H 5 . ? -14.420 31.237 42.252 1.00 25.67 ? 1357 HOH A O 1 HETATM 5275 O O . HOH H 5 . ? 25.017 33.678 49.448 1.00 26.26 ? 1358 HOH A O 1 HETATM 5276 O O . HOH H 5 . ? 17.584 -1.834 26.262 1.00 40.98 ? 1359 HOH A O 1 HETATM 5277 O O . HOH H 5 . ? -21.132 39.947 51.776 1.00 33.79 ? 1360 HOH A O 1 HETATM 5278 O O . HOH H 5 . ? 30.598 35.928 18.196 1.00 36.35 ? 1361 HOH A O 1 HETATM 5279 O O . HOH H 5 . ? 17.435 37.773 41.821 1.00 43.55 ? 1362 HOH A O 1 HETATM 5280 O O . HOH H 5 . ? 45.513 13.835 10.876 1.00 32.57 ? 1363 HOH A O 1 HETATM 5281 O O . HOH H 5 . ? -10.093 47.752 64.317 1.00 40.41 ? 1364 HOH A O 1 HETATM 5282 O O . HOH H 5 . ? 0.475 14.829 57.964 1.00 47.95 ? 1365 HOH A O 1 HETATM 5283 O O . HOH H 5 . ? 10.700 5.707 46.651 1.00 29.01 ? 1366 HOH A O 1 HETATM 5284 O O . HOH H 5 . ? 39.212 8.545 41.301 1.00 36.02 ? 1367 HOH A O 1 HETATM 5285 O O . HOH H 5 . ? -16.875 45.639 58.924 1.00 33.22 ? 1368 HOH A O 1 HETATM 5286 O O . HOH H 5 . ? -6.583 35.940 66.381 1.00 43.48 ? 1369 HOH A O 1 HETATM 5287 O O . HOH H 5 . ? 32.705 28.446 48.796 1.00 37.56 ? 1370 HOH A O 1 HETATM 5288 O O . HOH H 5 . ? 23.793 28.799 63.049 1.00 32.90 ? 1371 HOH A O 1 HETATM 5289 O O . HOH H 5 . ? 15.476 1.761 46.685 1.00 32.94 ? 1372 HOH A O 1 HETATM 5290 O O . HOH H 5 . ? 17.021 6.857 6.347 1.00 35.52 ? 1373 HOH A O 1 HETATM 5291 O O . HOH H 5 . ? -8.722 26.374 65.530 1.00 45.25 ? 1374 HOH A O 1 HETATM 5292 O O . HOH H 5 . ? 38.946 27.289 17.306 1.00 41.49 ? 1375 HOH A O 1 HETATM 5293 O O . HOH H 5 . ? 1.316 21.307 18.222 1.00 36.68 ? 1376 HOH A O 1 HETATM 5294 O O . HOH H 5 . ? 21.824 -2.906 33.165 1.00 31.49 ? 1377 HOH A O 1 HETATM 5295 O O . HOH H 5 . ? 20.494 37.539 45.632 1.00 28.56 ? 1378 HOH A O 1 HETATM 5296 O O . HOH H 5 . ? 44.665 23.108 42.335 1.00 41.98 ? 1379 HOH A O 1 HETATM 5297 O O . HOH H 5 . ? 13.443 2.087 39.219 1.00 32.69 ? 1380 HOH A O 1 HETATM 5298 O O . HOH H 5 . ? 23.809 19.745 63.545 1.00 39.70 ? 1381 HOH A O 1 HETATM 5299 O O . HOH H 5 . ? 12.754 36.764 62.780 1.00 36.21 ? 1382 HOH A O 1 HETATM 5300 O O . HOH H 5 . ? 5.802 5.698 34.376 1.00 36.42 ? 1383 HOH A O 1 HETATM 5301 O O . HOH H 5 . ? 44.530 14.270 13.414 1.00 31.90 ? 1384 HOH A O 1 HETATM 5302 O O . HOH H 5 . ? 8.978 44.664 40.714 1.00 31.63 ? 1385 HOH A O 1 HETATM 5303 O O . HOH H 5 . ? 4.206 26.240 66.300 1.00 30.30 ? 1386 HOH A O 1 HETATM 5304 O O . HOH H 5 . ? 34.284 33.757 21.057 1.00 32.56 ? 1387 HOH A O 1 HETATM 5305 O O . HOH H 5 . ? 25.432 34.193 16.748 1.00 26.84 ? 1388 HOH A O 1 HETATM 5306 O O . HOH H 5 . ? -2.064 42.914 39.308 1.00 27.09 ? 1389 HOH A O 1 HETATM 5307 O O . HOH H 5 . ? 7.901 34.186 67.781 1.00 32.84 ? 1390 HOH A O 1 HETATM 5308 O O . HOH H 5 . ? -11.632 43.057 42.011 1.00 23.06 ? 1391 HOH A O 1 HETATM 5309 O O . HOH H 5 . ? 1.210 17.438 28.024 1.00 32.99 ? 1392 HOH A O 1 HETATM 5310 O O . HOH H 5 . ? 0.156 41.302 65.066 1.00 27.40 ? 1393 HOH A O 1 HETATM 5311 O O . HOH H 5 . ? 15.750 42.570 55.369 1.00 37.38 ? 1394 HOH A O 1 HETATM 5312 O O . HOH H 5 . ? 54.173 13.064 24.702 1.00 33.05 ? 1395 HOH A O 1 HETATM 5313 O O . HOH H 5 . ? -7.101 55.304 59.396 1.00 40.35 ? 1396 HOH A O 1 HETATM 5314 O O . HOH H 5 . ? 29.783 28.144 56.980 1.00 32.73 ? 1397 HOH A O 1 HETATM 5315 O O . HOH H 5 . ? 17.838 1.398 20.080 1.00 37.74 ? 1398 HOH A O 1 HETATM 5316 O O . HOH H 5 . ? 22.348 31.508 10.791 1.00 31.39 ? 1399 HOH A O 1 HETATM 5317 O O . HOH H 5 . ? 5.451 43.359 41.266 1.00 29.21 ? 1400 HOH A O 1 HETATM 5318 O O . HOH H 5 . ? 33.524 25.516 55.559 1.00 44.29 ? 1401 HOH A O 1 HETATM 5319 O O . HOH H 5 . ? 17.543 9.941 8.266 1.00 34.52 ? 1402 HOH A O 1 HETATM 5320 O O . HOH H 5 . ? 7.024 27.643 68.928 1.00 34.71 ? 1403 HOH A O 1 HETATM 5321 O O . HOH H 5 . ? 34.826 7.910 54.369 1.00 40.64 ? 1404 HOH A O 1 HETATM 5322 O O . HOH H 5 . ? -19.315 22.630 52.648 1.00 39.86 ? 1405 HOH A O 1 HETATM 5323 O O . HOH H 5 . ? -9.271 25.365 31.702 1.00 29.30 ? 1406 HOH A O 1 HETATM 5324 O O . HOH H 5 . ? 18.058 20.350 68.548 1.00 41.34 ? 1407 HOH A O 1 HETATM 5325 O O . HOH H 5 . ? 36.741 10.605 47.895 1.00 29.18 ? 1408 HOH A O 1 HETATM 5326 O O . HOH H 5 . ? 47.411 21.231 39.101 1.00 49.59 ? 1409 HOH A O 1 HETATM 5327 O O . HOH H 5 . ? -1.868 12.523 39.843 1.00 30.47 ? 1410 HOH A O 1 HETATM 5328 O O . HOH H 5 . ? -0.995 15.571 45.950 1.00 25.31 ? 1411 HOH A O 1 HETATM 5329 O O . HOH H 5 . ? 36.665 31.260 16.732 1.00 32.63 ? 1412 HOH A O 1 HETATM 5330 O O . HOH H 5 . ? -5.564 31.841 34.485 1.00 47.94 ? 1413 HOH A O 1 HETATM 5331 O O . HOH H 5 . ? 2.466 16.347 19.981 1.00 45.25 ? 1414 HOH A O 1 HETATM 5332 O O . HOH H 5 . ? 42.807 28.936 14.302 1.00 38.90 ? 1415 HOH A O 1 HETATM 5333 O O . HOH H 5 . ? 32.508 33.529 13.424 1.00 32.25 ? 1416 HOH A O 1 HETATM 5334 O O . HOH H 5 . ? 5.114 36.485 44.871 1.00 25.09 ? 1417 HOH A O 1 HETATM 5335 O O . HOH H 5 . ? 24.036 25.186 62.559 1.00 30.67 ? 1418 HOH A O 1 HETATM 5336 O O . HOH H 5 . ? 17.799 8.875 54.450 1.00 35.15 ? 1419 HOH A O 1 HETATM 5337 O O . HOH H 5 . ? 32.982 1.280 17.422 1.00 28.89 ? 1420 HOH A O 1 HETATM 5338 O O . HOH H 5 . ? 6.859 37.076 67.551 1.00 36.05 ? 1421 HOH A O 1 HETATM 5339 O O . HOH H 5 . ? 3.410 48.015 57.895 1.00 33.91 ? 1422 HOH A O 1 HETATM 5340 O O . HOH H 5 . ? 30.001 0.209 9.425 1.00 34.70 ? 1423 HOH A O 1 HETATM 5341 O O . HOH H 5 . ? 29.941 33.428 30.660 1.00 34.23 ? 1424 HOH A O 1 HETATM 5342 O O . HOH H 5 . ? -9.780 17.807 56.593 1.00 55.95 ? 1425 HOH A O 1 HETATM 5343 O O . HOH H 5 . ? 2.282 45.378 42.419 1.00 27.72 ? 1426 HOH A O 1 HETATM 5344 O O . HOH H 5 . ? 22.648 35.534 32.479 1.00 47.71 ? 1427 HOH A O 1 HETATM 5345 O O . HOH H 5 . ? 32.354 19.095 3.023 1.00 29.85 ? 1428 HOH A O 1 HETATM 5346 O O . HOH H 5 . ? -8.116 29.902 33.446 1.00 32.72 ? 1429 HOH A O 1 HETATM 5347 O O . HOH H 5 . ? 18.361 0.002 4.241 1.00 42.72 ? 1430 HOH A O 1 HETATM 5348 O O . HOH H 5 . ? 19.874 2.173 46.005 1.00 37.76 ? 1431 HOH A O 1 HETATM 5349 O O . HOH H 5 . ? 22.492 3.315 45.969 1.00 36.26 ? 1432 HOH A O 1 HETATM 5350 O O . HOH H 5 . ? -0.775 33.293 67.595 1.00 46.82 ? 1433 HOH A O 1 HETATM 5351 O O . HOH H 5 . ? 22.846 6.745 55.603 1.00 43.92 ? 1434 HOH A O 1 HETATM 5352 O O . HOH H 5 . ? 2.589 48.647 45.670 1.00 36.02 ? 1435 HOH A O 1 HETATM 5353 O O . HOH H 5 . ? 11.909 7.679 17.053 1.00 35.61 ? 1436 HOH A O 1 HETATM 5354 O O . HOH H 5 . ? -4.356 12.970 40.328 1.00 47.93 ? 1437 HOH A O 1 HETATM 5355 O O . HOH H 5 . ? 45.192 27.590 32.688 1.00 37.59 ? 1438 HOH A O 1 HETATM 5356 O O . HOH H 5 . ? -4.865 19.571 35.793 1.00 32.28 ? 1439 HOH A O 1 HETATM 5357 O O . HOH H 5 . ? 11.663 1.993 33.760 1.00 33.45 ? 1440 HOH A O 1 HETATM 5358 O O . HOH H 5 . ? -3.244 38.214 35.353 1.00 45.12 ? 1441 HOH A O 1 HETATM 5359 O O . HOH H 5 . ? 26.753 34.953 46.736 1.00 33.45 ? 1442 HOH A O 1 HETATM 5360 O O . HOH H 5 . ? 2.213 6.415 35.493 1.00 43.50 ? 1443 HOH A O 1 HETATM 5361 O O . HOH H 5 . ? 34.836 32.310 12.763 1.00 34.05 ? 1444 HOH A O 1 HETATM 5362 O O . HOH H 5 . ? -19.619 38.856 55.421 1.00 28.95 ? 1445 HOH A O 1 HETATM 5363 O O . HOH H 5 . ? -16.405 47.581 55.055 1.00 34.52 ? 1446 HOH A O 1 HETATM 5364 O O . HOH H 5 . ? 17.252 40.279 46.111 1.00 43.15 ? 1447 HOH A O 1 HETATM 5365 O O . HOH H 5 . ? 37.373 5.987 14.358 1.00 30.85 ? 1448 HOH A O 1 HETATM 5366 O O . HOH H 5 . ? 29.612 5.022 2.576 1.00 37.69 ? 1449 HOH A O 1 HETATM 5367 O O . HOH H 5 . ? 5.718 44.854 64.131 1.00 47.71 ? 1450 HOH A O 1 HETATM 5368 O O . HOH H 5 . ? 22.885 37.388 37.452 1.00 32.68 ? 1451 HOH A O 1 HETATM 5369 O O . HOH H 5 . ? 25.426 37.245 29.057 1.00 40.51 ? 1452 HOH A O 1 HETATM 5370 O O . HOH H 5 . ? -8.697 16.777 49.949 1.00 38.33 ? 1453 HOH A O 1 HETATM 5371 O O . HOH H 5 . ? 12.761 4.114 47.696 1.00 36.00 ? 1454 HOH A O 1 HETATM 5372 O O . HOH H 5 . ? 26.531 29.842 60.605 1.00 36.21 ? 1455 HOH A O 1 HETATM 5373 O O . HOH H 5 . ? 34.264 3.157 21.842 1.00 33.10 ? 1456 HOH A O 1 HETATM 5374 O O . HOH H 5 . ? 10.207 18.621 68.284 1.00 41.06 ? 1457 HOH A O 1 HETATM 5375 O O . HOH H 5 . ? 11.351 8.689 12.677 1.00 36.44 ? 1458 HOH A O 1 HETATM 5376 O O . HOH H 5 . ? 8.632 43.361 62.883 1.00 37.47 ? 1459 HOH A O 1 HETATM 5377 O O . HOH H 5 . ? 11.544 24.347 71.903 1.00 49.60 ? 1460 HOH A O 1 HETATM 5378 O O . HOH H 5 . ? -13.914 46.685 61.502 1.00 35.86 ? 1461 HOH A O 1 HETATM 5379 O O . HOH H 5 . ? 47.162 12.338 17.388 1.00 41.62 ? 1462 HOH A O 1 HETATM 5380 O O . HOH H 5 . ? 2.352 40.691 66.291 1.00 36.26 ? 1463 HOH A O 1 HETATM 5381 O O . HOH H 5 . ? 8.037 4.917 22.190 1.00 36.61 ? 1464 HOH A O 1 HETATM 5382 O O . HOH H 5 . ? 3.470 18.327 14.556 1.00 48.14 ? 1465 HOH A O 1 HETATM 5383 O O . HOH H 5 . ? 8.785 40.804 66.045 1.00 38.95 ? 1466 HOH A O 1 HETATM 5384 O O . HOH H 5 . ? -6.483 21.426 61.284 1.00 40.94 ? 1467 HOH A O 1 HETATM 5385 O O . HOH H 5 . ? -2.432 51.723 50.327 1.00 38.82 ? 1468 HOH A O 1 HETATM 5386 O O . HOH H 5 . ? 16.341 25.365 68.603 1.00 39.27 ? 1469 HOH A O 1 HETATM 5387 O O . HOH H 5 . ? -16.088 29.337 53.717 1.00 46.28 ? 1470 HOH A O 1 HETATM 5388 O O . HOH H 5 . ? -20.443 34.919 52.691 1.00 38.90 ? 1471 HOH A O 1 HETATM 5389 O O . HOH H 5 . ? 38.299 1.408 21.867 1.00 34.13 ? 1472 HOH A O 1 HETATM 5390 O O . HOH H 5 . ? 6.511 32.379 69.050 1.00 39.27 ? 1473 HOH A O 1 HETATM 5391 O O . HOH H 5 . ? 41.910 9.918 36.555 1.00 42.94 ? 1474 HOH A O 1 HETATM 5392 O O . HOH H 5 . ? -17.103 21.734 53.850 1.00 40.60 ? 1475 HOH A O 1 HETATM 5393 O O . HOH H 5 . ? 28.912 1.232 50.294 1.00 40.45 ? 1476 HOH A O 1 HETATM 5394 O O . HOH H 5 . ? 46.078 5.830 19.128 1.00 46.60 ? 1477 HOH A O 1 HETATM 5395 O O . HOH H 5 . ? 17.595 3.714 54.787 1.00 58.53 ? 1478 HOH A O 1 HETATM 5396 O O . HOH H 5 . ? 3.561 25.588 9.997 1.00 48.51 ? 1479 HOH A O 1 HETATM 5397 O O . HOH H 5 . ? 27.661 20.076 58.224 1.00 46.50 ? 1480 HOH A O 1 HETATM 5398 O O . HOH H 5 . ? 21.256 12.532 8.851 1.00 39.51 ? 1481 HOH A O 1 HETATM 5399 O O . HOH H 5 . ? 3.904 39.932 30.719 1.00 43.90 ? 1482 HOH A O 1 HETATM 5400 O O . HOH H 5 . ? -13.143 25.333 66.227 1.00 26.97 ? 1483 HOH A O 1 HETATM 5401 O O . HOH H 5 . ? 9.471 40.983 28.016 1.00 41.27 ? 1484 HOH A O 1 HETATM 5402 O O . HOH H 5 . ? 10.781 19.730 11.027 1.00 47.45 ? 1485 HOH A O 1 HETATM 5403 O O . HOH H 5 . ? 13.617 27.847 11.059 1.00 28.17 ? 1486 HOH A O 1 HETATM 5404 O O . HOH H 5 . ? 31.058 16.187 0.393 1.00 50.62 ? 1487 HOH A O 1 HETATM 5405 O O . HOH H 5 . ? 6.375 9.316 49.104 1.00 44.36 ? 1488 HOH A O 1 HETATM 5406 O O . HOH H 5 . ? 29.767 28.650 46.649 1.00 38.31 ? 1489 HOH A O 1 HETATM 5407 O O . HOH H 5 . ? 39.344 4.607 38.888 1.00 39.19 ? 1490 HOH A O 1 HETATM 5408 O O . HOH H 5 . ? -1.640 24.759 65.116 1.00 37.99 ? 1491 HOH A O 1 HETATM 5409 O O . HOH H 5 . ? 23.490 17.010 5.930 1.00 39.91 ? 1492 HOH A O 1 HETATM 5410 O O . HOH H 5 . ? 3.656 50.633 56.796 1.00 41.53 ? 1493 HOH A O 1 HETATM 5411 O O . HOH H 5 . ? 5.778 46.734 57.059 1.00 31.22 ? 1494 HOH A O 1 HETATM 5412 O O . HOH H 5 . ? 33.534 34.339 16.705 1.00 36.61 ? 1495 HOH A O 1 HETATM 5413 O O . HOH H 5 . ? 4.785 12.211 22.190 1.00 52.61 ? 1496 HOH A O 1 HETATM 5414 O O . HOH H 5 . ? 5.718 29.289 11.286 1.00 31.86 ? 1497 HOH A O 1 HETATM 5415 O O . HOH H 5 . ? 5.591 28.564 13.903 1.00 28.66 ? 1498 HOH A O 1 HETATM 5416 O O . HOH H 5 . ? 34.284 30.953 30.162 1.00 38.59 ? 1499 HOH A O 1 HETATM 5417 O O . HOH H 5 . ? 18.264 6.444 53.460 1.00 43.33 ? 1500 HOH A O 1 HETATM 5418 O O . HOH H 5 . ? 16.485 29.257 10.858 1.00 33.55 ? 1501 HOH A O 1 HETATM 5419 O O . HOH H 5 . ? 7.894 45.539 49.985 1.00 34.29 ? 1502 HOH A O 1 HETATM 5420 O O . HOH H 5 . ? 4.584 30.479 15.489 1.00 28.32 ? 1503 HOH A O 1 HETATM 5421 O O . HOH H 5 . ? 8.608 12.221 59.811 1.00 39.96 ? 1504 HOH A O 1 HETATM 5422 O O . HOH H 5 . ? 1.969 27.143 65.011 1.00 37.37 ? 1505 HOH A O 1 HETATM 5423 O O . HOH H 5 . ? 24.894 2.144 51.590 1.00 46.00 ? 1506 HOH A O 1 HETATM 5424 O O . HOH H 5 . ? 31.903 -1.328 17.340 1.00 42.24 ? 1507 HOH A O 1 HETATM 5425 O O . HOH H 5 . ? 12.308 32.772 66.255 1.00 42.88 ? 1508 HOH A O 1 HETATM 5426 O O . HOH H 5 . ? 9.412 42.823 35.543 1.00 40.52 ? 1509 HOH A O 1 HETATM 5427 O O . HOH H 5 . ? 1.992 46.636 63.709 1.00 38.50 ? 1510 HOH A O 1 HETATM 5428 O O . HOH H 5 . ? 15.850 41.157 40.230 1.00 26.65 ? 1511 HOH A O 1 HETATM 5429 O O . HOH H 5 . ? 5.668 17.925 64.223 1.00 33.93 ? 1512 HOH A O 1 HETATM 5430 O O . HOH H 5 . ? 5.123 23.289 66.009 1.00 31.07 ? 1513 HOH A O 1 HETATM 5431 O O . HOH H 5 . ? -17.871 30.790 58.936 1.00 33.18 ? 1514 HOH A O 1 HETATM 5432 O O . HOH H 5 . ? 1.764 30.261 22.617 1.00 28.15 ? 1515 HOH A O 1 HETATM 5433 O O . HOH H 5 . ? 30.930 32.659 47.837 1.00 40.60 ? 1516 HOH A O 1 HETATM 5434 O O . HOH H 5 . ? 37.570 24.450 44.941 1.00 39.65 ? 1517 HOH A O 1 HETATM 5435 O O . HOH H 5 . ? 34.780 5.148 5.334 1.00 36.27 ? 1518 HOH A O 1 HETATM 5436 O O . HOH H 5 . ? 23.358 -4.450 31.625 1.00 41.26 ? 1519 HOH A O 1 HETATM 5437 O O . HOH H 5 . ? -15.577 30.837 55.714 1.00 34.35 ? 1520 HOH A O 1 HETATM 5438 O O . HOH H 5 . ? 27.504 -2.537 15.704 1.00 45.34 ? 1521 HOH A O 1 HETATM 5439 O O . HOH H 5 . ? 7.203 -2.182 24.768 1.00 53.35 ? 1522 HOH A O 1 HETATM 5440 O O . HOH H 5 . ? 23.881 21.799 65.016 1.00 47.72 ? 1523 HOH A O 1 HETATM 5441 O O . HOH H 5 . ? 37.425 22.880 9.569 1.00 40.69 ? 1524 HOH A O 1 HETATM 5442 O O . HOH H 5 . ? 7.639 40.935 26.158 1.00 45.42 ? 1525 HOH A O 1 HETATM 5443 O O . HOH H 5 . ? 35.561 5.993 50.401 1.00 41.30 ? 1526 HOH A O 1 HETATM 5444 O O . HOH H 5 . ? 26.807 24.742 60.919 1.00 41.36 ? 1527 HOH A O 1 HETATM 5445 O O . HOH H 5 . ? 26.560 17.511 5.072 1.00 34.64 ? 1528 HOH A O 1 HETATM 5446 O O . HOH H 5 . ? 27.932 34.606 39.198 1.00 43.88 ? 1529 HOH A O 1 HETATM 5447 O O . HOH H 5 . ? 14.281 5.486 21.220 1.00 36.00 ? 1530 HOH A O 1 HETATM 5448 O O . HOH H 5 . ? 13.196 40.045 60.668 1.00 41.64 ? 1531 HOH A O 1 HETATM 5449 O O . HOH H 5 . ? -11.122 28.097 32.663 1.00 39.96 ? 1532 HOH A O 1 HETATM 5450 O O . HOH H 5 . ? 20.894 23.773 68.587 1.00 43.00 ? 1533 HOH A O 1 HETATM 5451 O O . HOH H 5 . ? -17.417 28.746 47.516 1.00 43.84 ? 1534 HOH A O 1 HETATM 5452 O O . HOH H 5 . ? 23.247 2.516 43.211 1.00 40.44 ? 1535 HOH A O 1 HETATM 5453 O O . HOH H 5 . ? -14.553 22.789 54.694 1.00 47.52 ? 1536 HOH A O 1 HETATM 5454 O O . HOH H 5 . ? 26.155 18.310 62.656 1.00 43.62 ? 1537 HOH A O 1 HETATM 5455 O O . HOH H 5 . ? -1.420 31.405 67.998 1.00 44.25 ? 1538 HOH A O 1 HETATM 5456 O O . HOH H 5 . ? 33.233 3.618 45.803 1.00 43.70 ? 1539 HOH A O 1 HETATM 5457 O O . HOH H 5 . ? 51.921 8.662 21.776 1.00 58.09 ? 1540 HOH A O 1 HETATM 5458 O O . HOH H 5 . ? 15.025 -0.714 33.427 1.00 39.91 ? 1541 HOH A O 1 HETATM 5459 O O . HOH H 5 . ? 29.838 35.370 26.075 1.00 39.78 ? 1542 HOH A O 1 HETATM 5460 O O . HOH H 5 . ? 17.843 0.034 24.474 1.00 32.80 ? 1543 HOH A O 1 HETATM 5461 O O . HOH H 5 . ? -2.989 16.716 33.181 1.00 35.60 ? 1544 HOH A O 1 HETATM 5462 O O . HOH H 5 . ? 3.089 6.940 39.638 1.00 38.44 ? 1545 HOH A O 1 HETATM 5463 O O . HOH H 5 . ? 35.880 2.872 27.542 1.00 45.61 ? 1546 HOH A O 1 HETATM 5464 O O . HOH H 5 . ? 26.071 35.008 41.299 1.00 32.40 ? 1547 HOH A O 1 HETATM 5465 O O . HOH H 5 . ? 8.308 1.285 30.608 1.00 53.53 ? 1548 HOH A O 1 HETATM 5466 O O . HOH H 5 . ? -13.184 22.840 40.844 1.00 54.52 ? 1549 HOH A O 1 HETATM 5467 O O . HOH H 5 . ? 9.743 5.620 20.173 1.00 39.08 ? 1550 HOH A O 1 HETATM 5468 O O . HOH H 5 . ? 5.503 49.596 50.162 1.00 49.02 ? 1551 HOH A O 1 HETATM 5469 O O . HOH H 5 . ? 24.187 11.946 57.180 1.00 45.46 ? 1552 HOH A O 1 HETATM 5470 O O . HOH H 5 . ? 4.251 8.732 46.376 1.00 44.24 ? 1553 HOH A O 1 HETATM 5471 O O . HOH H 5 . ? 27.045 7.633 57.109 1.00 41.13 ? 1554 HOH A O 1 HETATM 5472 O O . HOH H 5 . ? 33.330 2.628 42.366 1.00 47.57 ? 1555 HOH A O 1 HETATM 5473 O O . HOH H 5 . ? -1.408 45.917 41.434 1.00 37.31 ? 1556 HOH A O 1 HETATM 5474 O O . HOH H 5 . ? 32.849 0.727 10.490 1.00 41.51 ? 1557 HOH A O 1 HETATM 5475 O O . HOH H 5 . ? 48.243 18.567 32.283 1.00 47.63 ? 1558 HOH A O 1 HETATM 5476 O O . HOH H 5 . ? -5.809 46.257 42.878 1.00 41.69 ? 1559 HOH A O 1 HETATM 5477 O O . HOH H 5 . ? 19.072 3.718 50.354 1.00 36.09 ? 1560 HOH A O 1 HETATM 5478 O O . HOH H 5 . ? 34.590 24.522 7.699 1.00 37.12 ? 1561 HOH A O 1 HETATM 5479 O O . HOH H 5 . ? 0.908 9.703 41.859 1.00 39.38 ? 1562 HOH A O 1 HETATM 5480 O O . HOH H 5 . ? 8.777 2.554 24.734 1.00 36.14 ? 1563 HOH A O 1 HETATM 5481 O O . HOH H 5 . ? 42.281 2.778 20.211 1.00 37.51 ? 1564 HOH A O 1 HETATM 5482 O O . HOH H 5 . ? 1.363 33.908 20.762 1.00 37.96 ? 1565 HOH A O 1 HETATM 5483 O O . HOH H 5 . ? 50.377 11.127 17.908 1.00 42.92 ? 1566 HOH A O 1 HETATM 5484 O O . HOH H 5 . ? 30.930 1.121 52.549 1.00 47.03 ? 1567 HOH A O 1 HETATM 5485 O O . HOH H 5 . ? 44.702 2.905 27.409 1.00 57.14 ? 1568 HOH A O 1 HETATM 5486 O O . HOH H 5 . ? -5.660 22.803 63.179 1.00 45.52 ? 1569 HOH A O 1 HETATM 5487 O O . HOH H 5 . ? -4.557 50.530 49.034 1.00 29.94 ? 1570 HOH A O 1 HETATM 5488 O O . HOH H 5 . ? 22.642 -1.725 40.501 1.00 53.77 ? 1571 HOH A O 1 HETATM 5489 O O . HOH H 5 . ? 17.615 -2.458 37.299 1.00 43.95 ? 1572 HOH A O 1 HETATM 5490 O O . HOH H 5 . ? -0.782 29.221 24.595 1.00 23.80 ? 1573 HOH A O 1 HETATM 5491 O O . HOH H 5 . ? 32.598 34.816 26.476 1.00 53.24 ? 1574 HOH A O 1 HETATM 5492 O O . HOH H 5 . ? -2.198 27.156 66.966 1.00 46.79 ? 1575 HOH A O 1 HETATM 5493 O O . HOH H 5 . ? 3.816 34.290 17.646 1.00 40.20 ? 1576 HOH A O 1 HETATM 5494 O O . HOH H 5 . ? -8.715 32.819 70.912 1.00 48.77 ? 1577 HOH A O 1 HETATM 5495 O O . HOH H 5 . ? 29.410 -2.360 13.418 1.00 46.98 ? 1578 HOH A O 1 HETATM 5496 O O . HOH H 5 . ? 35.753 1.737 25.618 1.00 47.01 ? 1579 HOH A O 1 HETATM 5497 O O . HOH H 5 . ? 6.598 5.953 44.028 1.00 37.92 ? 1580 HOH A O 1 HETATM 5498 O O . HOH H 5 . ? 29.373 -3.694 30.628 1.00 59.90 ? 1581 HOH A O 1 HETATM 5499 O O . HOH H 5 . ? -17.618 28.424 44.771 1.00 38.51 ? 1582 HOH A O 1 HETATM 5500 O O . HOH H 5 . ? 39.057 20.905 8.595 1.00 32.83 ? 1583 HOH A O 1 HETATM 5501 O O . HOH H 5 . ? 4.995 6.097 40.236 1.00 46.43 ? 1584 HOH A O 1 HETATM 5502 O O . HOH H 5 . ? 6.745 39.793 24.046 1.00 43.60 ? 1585 HOH A O 1 HETATM 5503 O O . HOH H 5 . ? 19.005 16.428 7.315 1.00 50.82 ? 1586 HOH A O 1 HETATM 5504 O O . HOH H 5 . ? 4.230 48.388 60.524 1.00 36.86 ? 1587 HOH A O 1 HETATM 5505 O O . HOH H 5 . ? 33.194 5.356 58.065 1.00 52.82 ? 1588 HOH A O 1 HETATM 5506 O O . HOH H 5 . ? -12.169 23.307 64.439 1.00 50.67 ? 1589 HOH A O 1 HETATM 5507 O O . HOH H 5 . ? 24.989 9.573 0.651 1.00 52.29 ? 1590 HOH A O 1 HETATM 5508 O O . HOH H 5 . ? -8.771 45.770 39.130 1.00 47.86 ? 1591 HOH A O 1 HETATM 5509 O O . HOH H 5 . ? 19.764 5.233 3.390 1.00 42.79 ? 1592 HOH A O 1 HETATM 5510 O O . HOH H 5 . ? 12.424 6.824 10.985 1.00 45.34 ? 1593 HOH A O 1 HETATM 5511 O O . HOH H 5 . ? -10.778 48.208 45.396 1.00 38.58 ? 1594 HOH A O 1 HETATM 5512 O O . HOH H 5 . ? 37.365 30.196 21.797 1.00 25.79 ? 1595 HOH A O 1 HETATM 5513 O O . HOH H 5 . ? 2.165 40.006 29.298 1.00 48.17 ? 1596 HOH A O 1 HETATM 5514 O O . HOH H 5 . ? 21.456 34.467 50.312 1.00 46.98 ? 1597 HOH A O 1 HETATM 5515 O O . HOH H 5 . ? 11.085 44.373 43.710 1.00 35.90 ? 1598 HOH A O 1 HETATM 5516 O O . HOH H 5 . ? 15.807 24.108 7.616 1.00 56.73 ? 1599 HOH A O 1 HETATM 5517 O O . HOH H 5 . ? -15.189 27.000 47.421 1.00 30.07 ? 1600 HOH A O 1 HETATM 5518 O O . HOH H 5 . ? 10.528 5.076 43.539 1.00 38.04 ? 1601 HOH A O 1 HETATM 5519 O O . HOH H 5 . ? 24.747 32.544 29.640 1.00 17.74 ? 1602 HOH A O 1 HETATM 5520 O O . HOH H 5 . ? 2.779 30.652 68.117 1.00 32.93 ? 1603 HOH A O 1 HETATM 5521 O O . HOH H 5 . ? 36.232 6.186 45.845 1.00 42.75 ? 1604 HOH A O 1 HETATM 5522 O O . HOH H 5 . ? 16.330 6.222 16.493 1.00 33.92 ? 1605 HOH A O 1 HETATM 5523 O O . HOH H 5 . ? 9.554 14.080 65.152 1.00 54.23 ? 1606 HOH A O 1 HETATM 5524 O O . HOH H 5 . ? 12.435 41.731 62.018 1.00 44.02 ? 1607 HOH A O 1 HETATM 5525 O O . HOH H 5 . ? 22.346 -2.437 35.786 1.00 48.85 ? 1608 HOH A O 1 HETATM 5526 O O . HOH H 5 . ? 14.535 40.047 42.392 1.00 27.82 ? 1609 HOH A O 1 HETATM 5527 O O . HOH H 5 . ? 6.513 8.506 24.523 1.00 27.96 ? 1610 HOH A O 1 HETATM 5528 O O . HOH H 5 . ? 39.783 6.839 31.684 1.00 28.08 ? 1611 HOH A O 1 HETATM 5529 O O . HOH H 5 . ? 27.480 32.869 50.541 1.00 32.79 ? 1612 HOH A O 1 HETATM 5530 O O . HOH H 5 . ? 35.467 30.019 8.320 1.00 48.66 ? 1613 HOH A O 1 HETATM 5531 O O . HOH H 5 . ? 27.577 -1.699 21.378 1.00 43.96 ? 1614 HOH A O 1 HETATM 5532 O O . HOH H 5 . ? 27.029 17.404 60.455 1.00 51.35 ? 1615 HOH A O 1 HETATM 5533 O O . HOH H 5 . ? 30.371 29.857 48.977 1.00 37.36 ? 1616 HOH A O 1 HETATM 5534 O O . HOH H 5 . ? -16.690 49.760 60.639 1.00 45.63 ? 1617 HOH A O 1 HETATM 5535 O O . HOH H 5 . ? 27.664 34.558 44.169 1.00 36.93 ? 1618 HOH A O 1 HETATM 5536 O O . HOH H 5 . ? 32.966 16.818 2.164 1.00 28.73 ? 1619 HOH A O 1 HETATM 5537 O O . HOH H 5 . ? 15.511 3.150 22.261 1.00 33.39 ? 1620 HOH A O 1 HETATM 5538 O O . HOH H 5 . ? 33.999 10.940 55.193 1.00 33.56 ? 1621 HOH A O 1 HETATM 5539 O O . HOH H 5 . ? 11.106 -1.733 30.970 1.00 42.39 ? 1622 HOH A O 1 HETATM 5540 O O . HOH H 5 . ? -0.314 11.655 46.750 1.00 51.49 ? 1623 HOH A O 1 HETATM 5541 O O . HOH H 5 . ? 16.610 3.920 4.641 1.00 48.33 ? 1624 HOH A O 1 HETATM 5542 O O . HOH H 5 . ? -7.280 20.667 35.913 1.00 55.12 ? 1625 HOH A O 1 HETATM 5543 O O . HOH H 5 . ? -5.404 37.852 67.870 1.00 42.63 ? 1626 HOH A O 1 HETATM 5544 O O . HOH H 5 . ? 33.490 3.248 6.775 1.00 44.48 ? 1627 HOH A O 1 HETATM 5545 O O . HOH H 5 . ? -11.017 26.249 41.670 1.00 39.67 ? 1628 HOH A O 1 HETATM 5546 O O . HOH H 5 . ? -0.200 31.499 26.876 1.00 27.69 ? 1629 HOH A O 1 HETATM 5547 O O . HOH H 5 . ? 26.391 15.939 54.612 1.00 32.33 ? 1630 HOH A O 1 HETATM 5548 O O . HOH H 5 . ? 28.492 -0.635 5.446 1.00 54.97 ? 1631 HOH A O 1 HETATM 5549 O O . HOH H 5 . ? 11.340 1.652 36.998 1.00 44.15 ? 1632 HOH A O 1 HETATM 5550 O O . HOH H 5 . ? 28.300 34.659 18.740 1.00 32.66 ? 1633 HOH A O 1 HETATM 5551 O O . HOH H 5 . ? 14.601 10.888 64.374 1.00 46.14 ? 1634 HOH A O 1 HETATM 5552 O O . HOH H 5 . ? -8.049 18.025 47.712 1.00 42.72 ? 1635 HOH A O 1 HETATM 5553 O O . HOH H 5 . ? 6.649 10.263 21.987 1.00 36.24 ? 1636 HOH A O 1 HETATM 5554 O O . HOH H 5 . ? -1.957 54.541 55.233 1.00 34.47 ? 1637 HOH A O 1 HETATM 5555 O O . HOH H 5 . ? -3.997 49.404 45.210 1.00 44.14 ? 1638 HOH A O 1 HETATM 5556 O O . HOH H 5 . ? 31.791 29.747 53.054 1.00 38.63 ? 1639 HOH A O 1 HETATM 5557 O O . HOH H 5 . ? 31.649 0.495 31.465 1.00 41.01 ? 1640 HOH A O 1 HETATM 5558 O O . HOH H 5 . ? 15.664 37.059 13.150 1.00 33.07 ? 1641 HOH A O 1 HETATM 5559 O O . HOH H 5 . ? 28.593 35.118 11.682 1.00 44.82 ? 1642 HOH A O 1 HETATM 5560 O O . HOH H 5 . ? 38.959 10.792 49.336 1.00 50.80 ? 1643 HOH A O 1 HETATM 5561 O O . HOH H 5 . ? 4.729 19.686 65.291 1.00 39.91 ? 1644 HOH A O 1 HETATM 5562 O O . HOH H 5 . ? 48.952 17.778 34.494 1.00 53.00 ? 1645 HOH A O 1 HETATM 5563 O O . HOH H 5 . ? 10.062 46.460 58.518 1.00 41.96 ? 1646 HOH A O 1 HETATM 5564 O O . HOH H 5 . ? 18.321 0.013 17.552 1.00 35.78 ? 1647 HOH A O 1 HETATM 5565 O O . HOH H 5 . ? -2.327 13.811 44.465 1.00 45.53 ? 1648 HOH A O 1 HETATM 5566 O O . HOH H 5 . ? -3.176 29.927 28.504 1.00 25.11 ? 1649 HOH A O 1 HETATM 5567 O O . HOH H 5 . ? -10.632 28.978 30.119 1.00 25.07 ? 1650 HOH A O 1 HETATM 5568 O O . HOH H 5 . ? 17.793 35.826 48.938 1.00 36.26 ? 1651 HOH A O 1 HETATM 5569 O O . HOH H 5 . ? 13.033 8.893 14.700 1.00 27.26 ? 1652 HOH A O 1 HETATM 5570 O O . HOH H 5 . ? 13.895 42.327 44.301 1.00 32.27 ? 1653 HOH A O 1 HETATM 5571 O O . HOH H 5 . ? 5.194 27.703 9.317 1.00 34.63 ? 1654 HOH A O 1 HETATM 5572 O O . HOH H 5 . ? 10.654 41.970 50.701 1.00 51.08 ? 1655 HOH A O 1 HETATM 5573 O O . HOH H 5 . ? 29.282 17.959 56.904 1.00 31.34 ? 1656 HOH A O 1 HETATM 5574 O O . HOH H 5 . ? -8.493 24.482 63.627 1.00 60.14 ? 1657 HOH A O 1 HETATM 5575 O O . HOH H 5 . ? -18.253 47.561 53.014 1.00 38.82 ? 1658 HOH A O 1 HETATM 5576 O O . HOH H 5 . ? 24.662 -1.449 23.478 1.00 51.88 ? 1659 HOH A O 1 HETATM 5577 O O . HOH H 5 . ? 2.217 29.057 16.359 1.00 46.61 ? 1660 HOH A O 1 HETATM 5578 O O . HOH H 5 . ? 8.740 27.673 8.839 1.00 38.91 ? 1661 HOH A O 1 HETATM 5579 O O . HOH H 5 . ? 4.936 38.732 19.761 1.00 36.47 ? 1662 HOH A O 1 HETATM 5580 O O . HOH H 5 . ? 2.297 25.519 11.928 1.00 49.77 ? 1663 HOH A O 1 HETATM 5581 O O . HOH H 5 . ? 52.684 11.127 20.685 1.00 37.04 ? 1664 HOH A O 1 HETATM 5582 O O . HOH H 5 . ? 41.531 14.324 42.130 1.00 46.82 ? 1665 HOH A O 1 HETATM 5583 O O . HOH H 5 . ? -8.286 24.798 36.149 1.00 52.94 ? 1666 HOH A O 1 HETATM 5584 O O . HOH H 5 . ? -0.271 27.115 13.021 1.00 43.99 ? 1667 HOH A O 1 HETATM 5585 O O . HOH H 5 . ? 30.226 0.722 23.612 1.00 46.73 ? 1668 HOH A O 1 HETATM 5586 O O . HOH H 5 . ? 45.510 5.114 34.207 1.00 44.46 ? 1669 HOH A O 1 HETATM 5587 O O . HOH H 5 . ? -11.387 46.850 62.727 1.00 30.87 ? 1670 HOH A O 1 HETATM 5588 O O . HOH H 5 . ? 10.256 -0.041 32.750 1.00 42.03 ? 1671 HOH A O 1 HETATM 5589 O O . HOH H 5 . ? 37.559 5.360 30.775 1.00 42.01 ? 1672 HOH A O 1 HETATM 5590 O O . HOH H 5 . ? 1.238 33.064 23.211 1.00 29.78 ? 1673 HOH A O 1 HETATM 5591 O O . HOH H 5 . ? -5.531 15.186 38.365 1.00 44.55 ? 1674 HOH A O 1 HETATM 5592 O O . HOH H 5 . ? 6.178 40.969 30.766 1.00 40.36 ? 1675 HOH A O 1 HETATM 5593 O O . HOH H 5 . ? 19.486 30.725 9.231 1.00 50.38 ? 1676 HOH A O 1 HETATM 5594 O O . HOH H 5 . ? 18.404 40.774 35.945 1.00 43.19 ? 1677 HOH A O 1 HETATM 5595 O O . HOH H 5 . ? 15.596 35.330 52.130 1.00 48.69 ? 1678 HOH A O 1 HETATM 5596 O O . HOH H 5 . ? 14.595 35.973 11.673 1.00 31.51 ? 1679 HOH A O 1 HETATM 5597 O O . HOH H 5 . ? 8.438 44.593 46.349 1.00 45.23 ? 1680 HOH A O 1 HETATM 5598 O O . HOH H 5 . ? 37.927 2.854 31.712 1.00 41.27 ? 1681 HOH A O 1 HETATM 5599 O O . HOH H 5 . ? -8.780 45.383 64.940 1.00 42.93 ? 1682 HOH A O 1 HETATM 5600 O O . HOH H 5 . ? 10.949 39.949 32.187 1.00 36.67 ? 1683 HOH A O 1 HETATM 5601 O O . HOH H 5 . ? 26.684 13.009 57.580 1.00 49.20 ? 1684 HOH A O 1 HETATM 5602 O O . HOH H 5 . ? -0.627 55.262 61.377 1.00 39.49 ? 1685 HOH A O 1 HETATM 5603 O O . HOH H 5 . ? 6.701 10.178 51.959 1.00 35.44 ? 1686 HOH A O 1 HETATM 5604 O O . HOH H 5 . ? 13.180 43.690 50.980 1.00 44.87 ? 1687 HOH A O 1 HETATM 5605 O O . HOH H 5 . ? 12.132 42.654 28.804 1.00 40.06 ? 1688 HOH A O 1 HETATM 5606 O O . HOH H 5 . ? 9.526 38.328 66.644 1.00 50.34 ? 1689 HOH A O 1 HETATM 5607 O O . HOH H 5 . ? 16.527 39.148 50.073 1.00 41.00 ? 1690 HOH A O 1 HETATM 5608 O O . HOH H 5 . ? 17.644 39.379 39.930 1.00 45.90 ? 1691 HOH A O 1 HETATM 5609 O O . HOH H 5 . ? 35.069 21.523 55.675 1.00 39.67 ? 1692 HOH A O 1 HETATM 5610 O O . HOH H 5 . ? 36.258 20.418 53.511 1.00 35.62 ? 1693 HOH A O 1 HETATM 5611 O O . HOH H 5 . ? 37.439 3.329 37.435 1.00 40.56 ? 1694 HOH A O 1 HETATM 5612 O O . HOH H 5 . ? -11.390 39.820 61.456 1.00 26.57 ? 1695 HOH A O 1 HETATM 5613 O O . HOH H 5 . ? 9.132 14.114 10.371 1.00 46.75 ? 1696 HOH A O 1 HETATM 5614 O O . HOH H 5 . ? 14.893 34.104 15.639 1.00 22.08 ? 1697 HOH A O 1 HETATM 5615 O O . HOH H 5 . ? -1.464 16.912 31.380 1.00 49.40 ? 1698 HOH A O 1 HETATM 5616 O O . HOH H 5 . ? 35.424 -0.821 36.878 1.00 49.68 ? 1699 HOH A O 1 HETATM 5617 O O . HOH H 5 . ? 14.675 44.015 37.558 1.00 35.51 ? 1700 HOH A O 1 HETATM 5618 O O . HOH H 5 . ? 38.762 3.263 35.290 1.00 49.09 ? 1701 HOH A O 1 HETATM 5619 O O . HOH H 5 . ? 17.136 -0.262 41.134 1.00 48.27 ? 1702 HOH A O 1 HETATM 5620 O O . HOH H 5 . ? 37.534 29.786 34.912 1.00 51.70 ? 1703 HOH A O 1 HETATM 5621 O O . HOH H 5 . ? 8.832 20.794 70.355 1.00 45.60 ? 1704 HOH A O 1 HETATM 5622 O O . HOH H 5 . ? -2.657 29.127 71.691 1.00 55.68 ? 1705 HOH A O 1 HETATM 5623 O O . HOH H 5 . ? 0.250 14.355 29.879 1.00 40.24 ? 1706 HOH A O 1 HETATM 5624 O O . HOH H 5 . ? 2.995 45.183 35.434 1.00 48.08 ? 1707 HOH A O 1 HETATM 5625 O O . HOH H 5 . ? 31.559 -0.786 42.131 1.00 46.49 ? 1708 HOH A O 1 HETATM 5626 O O . HOH H 5 . ? 27.262 14.553 5.195 1.00 24.98 ? 1709 HOH A O 1 HETATM 5627 O O . HOH H 5 . ? 2.807 37.190 69.739 1.00 50.86 ? 1710 HOH A O 1 HETATM 5628 O O . HOH H 5 . ? 1.530 44.076 38.910 1.00 35.47 ? 1711 HOH A O 1 HETATM 5629 O O . HOH H 5 . ? 13.605 30.631 65.779 1.00 46.03 ? 1712 HOH A O 1 HETATM 5630 O O . HOH H 5 . ? 0.592 25.069 63.813 1.00 29.96 ? 1713 HOH A O 1 HETATM 5631 O O . HOH H 5 . ? -2.833 16.571 59.781 1.00 42.05 ? 1714 HOH A O 1 HETATM 5632 O O . HOH H 5 . ? 38.794 16.954 10.179 1.00 23.06 ? 1715 HOH A O 1 HETATM 5633 O O . HOH H 5 . ? -7.062 21.964 39.833 1.00 33.98 ? 1716 HOH A O 1 HETATM 5634 O O . HOH H 5 . ? -12.141 21.904 56.386 1.00 29.46 ? 1717 HOH A O 1 HETATM 5635 O O . HOH H 5 . ? 15.767 31.347 65.395 1.00 47.39 ? 1718 HOH A O 1 HETATM 5636 O O . HOH H 5 . ? 10.346 43.854 47.382 1.00 33.84 ? 1719 HOH A O 1 HETATM 5637 O O . HOH H 5 . ? 23.157 13.208 44.740 1.00 18.34 ? 1720 HOH A O 1 HETATM 5638 O O . HOH H 5 . ? 17.556 40.651 54.124 1.00 56.57 ? 1721 HOH A O 1 HETATM 5639 O O . HOH H 5 . ? -14.091 22.815 43.133 1.00 47.19 ? 1722 HOH A O 1 HETATM 5640 O O . HOH H 5 . ? 15.098 0.561 50.738 1.00 52.48 ? 1723 HOH A O 1 HETATM 5641 O O . HOH H 5 . ? 0.256 10.719 31.188 1.00 38.27 ? 1724 HOH A O 1 HETATM 5642 O O . HOH H 5 . ? 2.022 47.891 43.109 1.00 43.11 ? 1725 HOH A O 1 HETATM 5643 O O . HOH H 5 . ? -20.127 34.212 42.906 1.00 30.91 ? 1726 HOH A O 1 HETATM 5644 O O . HOH H 5 . ? 5.469 32.450 21.436 1.00 22.67 ? 1727 HOH A O 1 HETATM 5645 O O . HOH H 5 . ? -19.508 45.847 46.467 1.00 41.68 ? 1728 HOH A O 1 HETATM 5646 O O . HOH H 5 . ? 21.634 0.291 36.320 1.00 24.74 ? 1729 HOH A O 1 HETATM 5647 O O . HOH H 5 . ? -15.153 45.508 43.191 1.00 37.22 ? 1730 HOH A O 1 HETATM 5648 O O . HOH H 5 . ? 46.035 8.529 19.811 1.00 44.29 ? 1731 HOH A O 1 HETATM 5649 O O . HOH H 5 . ? -3.792 46.994 42.327 1.00 47.73 ? 1732 HOH A O 1 HETATM 5650 O O . HOH H 5 . ? 10.354 33.195 68.063 1.00 54.25 ? 1733 HOH A O 1 HETATM 5651 O O . HOH H 5 . ? 10.435 42.235 33.163 1.00 36.67 ? 1734 HOH A O 1 HETATM 5652 O O . HOH H 5 . ? 16.633 -1.128 13.664 1.00 44.27 ? 1735 HOH A O 1 HETATM 5653 O O . HOH H 5 . ? 3.114 14.415 21.844 1.00 40.12 ? 1736 HOH A O 1 HETATM 5654 O O . HOH H 5 . ? 34.952 1.814 19.468 1.00 32.04 ? 1737 HOH A O 1 HETATM 5655 O O . HOH H 5 . ? -4.551 20.009 32.070 1.00 40.69 ? 1738 HOH A O 1 HETATM 5656 O O . HOH H 5 . ? 44.498 11.836 14.546 1.00 42.75 ? 1739 HOH A O 1 HETATM 5657 O O . HOH H 5 . ? 35.039 4.648 48.254 1.00 39.41 ? 1740 HOH A O 1 HETATM 5658 O O . HOH H 5 . ? -15.717 29.604 57.825 1.00 45.81 ? 1741 HOH A O 1 HETATM 5659 O O . HOH H 5 . ? 51.949 17.190 33.525 1.00 49.08 ? 1742 HOH A O 1 HETATM 5660 O O . HOH H 5 . ? -5.321 40.564 35.671 1.00 35.63 ? 1743 HOH A O 1 HETATM 5661 O O . HOH H 5 . ? -8.465 30.683 29.435 1.00 34.44 ? 1744 HOH A O 1 HETATM 5662 O O . HOH H 5 . ? 20.141 4.038 -0.711 1.00 57.14 ? 1745 HOH A O 1 HETATM 5663 O O . HOH H 5 . ? 24.665 -1.754 2.689 1.00 52.96 ? 1746 HOH A O 1 HETATM 5664 O O . HOH H 5 . ? 43.543 13.608 37.706 1.00 44.77 ? 1747 HOH A O 1 HETATM 5665 O O . HOH H 5 . ? 19.162 25.491 68.915 1.00 50.10 ? 1748 HOH A O 1 HETATM 5666 O O . HOH H 5 . ? 46.754 19.429 40.352 1.00 60.19 ? 1749 HOH A O 1 HETATM 5667 O O . HOH H 5 . ? -0.238 31.099 20.965 1.00 37.08 ? 1750 HOH A O 1 HETATM 5668 O O . HOH H 5 . ? -0.886 43.247 67.254 1.00 45.67 ? 1751 HOH A O 1 HETATM 5669 O O . HOH H 5 . ? 14.387 5.412 12.545 1.00 40.02 ? 1752 HOH A O 1 HETATM 5670 O O . HOH H 5 . ? 22.731 8.850 2.342 1.00 42.59 ? 1753 HOH A O 1 HETATM 5671 O O . HOH H 5 . ? 31.705 18.610 58.340 1.00 42.59 ? 1754 HOH A O 1 HETATM 5672 O O . HOH H 5 . ? 44.189 9.996 35.531 1.00 46.14 ? 1755 HOH A O 1 HETATM 5673 O O . HOH H 5 . ? 2.085 52.606 55.245 1.00 53.32 ? 1756 HOH A O 1 HETATM 5674 O O . HOH H 5 . ? 17.235 -1.040 21.618 1.00 45.26 ? 1757 HOH A O 1 HETATM 5675 O O . HOH H 5 . ? -0.515 21.601 64.575 1.00 40.62 ? 1758 HOH A O 1 HETATM 5676 O O . HOH H 5 . ? 21.972 0.591 42.742 1.00 50.74 ? 1759 HOH A O 1 HETATM 5677 O O . HOH H 5 . ? -11.145 28.369 75.297 1.00 36.00 ? 1760 HOH A O 1 HETATM 5678 O O . HOH H 5 . ? 33.589 -0.277 13.428 1.00 53.33 ? 1761 HOH A O 1 HETATM 5679 O O . HOH H 5 . ? 7.654 3.855 38.896 1.00 56.85 ? 1762 HOH A O 1 HETATM 5680 O O . HOH H 5 . ? 17.834 38.226 52.835 1.00 43.96 ? 1763 HOH A O 1 HETATM 5681 O O . HOH H 5 . ? 43.682 24.333 47.490 1.00 60.62 ? 1764 HOH A O 1 HETATM 5682 O O . HOH H 5 . ? 22.123 -3.184 26.143 1.00 57.01 ? 1765 HOH A O 1 HETATM 5683 O O . HOH H 5 . ? -4.557 42.378 67.550 1.00 52.68 ? 1766 HOH A O 1 HETATM 5684 O O . HOH H 5 . ? 39.355 29.594 23.681 1.00 26.73 ? 1767 HOH A O 1 HETATM 5685 O O . HOH H 5 . ? 4.210 43.541 39.003 1.00 34.47 ? 1768 HOH A O 1 HETATM 5686 O O . HOH H 5 . ? 9.067 32.690 11.664 1.00 39.32 ? 1769 HOH A O 1 HETATM 5687 O O . HOH H 5 . ? 38.309 31.552 19.455 1.00 41.28 ? 1770 HOH A O 1 HETATM 5688 O O . HOH H 5 . ? 23.691 -2.860 10.104 1.00 53.26 ? 1771 HOH A O 1 HETATM 5689 O O . HOH H 5 . ? 36.040 33.285 15.140 1.00 43.97 ? 1772 HOH A O 1 HETATM 5690 O O . HOH H 5 . ? -8.196 43.449 37.366 1.00 48.20 ? 1773 HOH A O 1 HETATM 5691 O O . HOH H 5 . ? 26.694 33.144 60.560 1.00 44.48 ? 1774 HOH A O 1 HETATM 5692 O O . HOH H 5 . ? 35.043 1.529 2.274 1.00 42.71 ? 1775 HOH A O 1 HETATM 5693 O O . HOH H 5 . ? -11.780 50.168 47.212 1.00 48.17 ? 1776 HOH A O 1 HETATM 5694 O O . HOH H 5 . ? 42.406 4.090 17.376 1.00 52.93 ? 1777 HOH A O 1 HETATM 5695 O O . HOH H 5 . ? -7.435 16.623 42.386 1.00 39.19 ? 1778 HOH A O 1 HETATM 5696 O O . HOH H 5 . ? 11.729 38.388 64.838 1.00 39.30 ? 1779 HOH A O 1 HETATM 5697 O O . HOH H 5 . ? 30.925 32.154 33.134 1.00 37.11 ? 1780 HOH A O 1 HETATM 5698 O O . HOH H 5 . ? 28.853 -1.302 17.803 1.00 36.09 ? 1781 HOH A O 1 HETATM 5699 O O . HOH H 5 . ? 25.551 35.571 12.299 1.00 55.18 ? 1782 HOH A O 1 HETATM 5700 O O . HOH H 5 . ? 49.881 9.091 19.942 1.00 55.81 ? 1783 HOH A O 1 HETATM 5701 O O . HOH H 5 . ? 46.236 3.291 25.789 1.00 45.53 ? 1784 HOH A O 1 HETATM 5702 O O . HOH H 5 . ? 17.608 36.893 46.643 1.00 31.40 ? 1785 HOH A O 1 HETATM 5703 O O . HOH H 5 . ? 18.735 7.855 4.286 1.00 50.91 ? 1786 HOH A O 1 HETATM 5704 O O . HOH H 5 . ? 33.641 20.341 57.974 1.00 45.09 ? 1787 HOH A O 1 HETATM 5705 O O . HOH H 5 . ? -17.108 48.669 63.048 1.00 40.30 ? 1788 HOH A O 1 HETATM 5706 O O . HOH H 5 . ? 29.127 19.276 3.312 1.00 48.23 ? 1789 HOH A O 1 HETATM 5707 O O . HOH H 5 . ? 32.503 -3.015 37.823 1.00 62.03 ? 1790 HOH A O 1 HETATM 5708 O O . HOH H 5 . ? 18.317 2.295 48.140 1.00 43.99 ? 1791 HOH A O 1 HETATM 5709 O O . HOH H 5 . ? 24.558 9.071 56.600 1.00 45.88 ? 1792 HOH A O 1 HETATM 5710 O O . HOH H 5 . ? -0.357 11.538 56.025 1.00 60.51 ? 1793 HOH A O 1 HETATM 5711 O O . HOH H 5 . ? 12.876 43.155 34.761 1.00 42.98 ? 1794 HOH A O 1 HETATM 5712 O O . HOH H 5 . ? 30.606 31.212 40.219 1.00 51.34 ? 1795 HOH A O 1 HETATM 5713 O O . HOH H 5 . ? 26.670 35.143 32.974 1.00 46.71 ? 1796 HOH A O 1 HETATM 5714 O O . HOH H 5 . ? -9.980 40.094 37.099 1.00 48.66 ? 1797 HOH A O 1 HETATM 5715 O O . HOH H 5 . ? 40.198 19.240 10.226 1.00 23.94 ? 1798 HOH A O 1 HETATM 5716 O O . HOH H 5 . ? 9.392 8.512 16.812 1.00 29.87 ? 1799 HOH A O 1 HETATM 5717 O O . HOH H 5 . ? 48.619 20.743 27.644 1.00 37.32 ? 1800 HOH A O 1 HETATM 5718 O O . HOH H 5 . ? 24.880 34.370 10.137 1.00 45.71 ? 1801 HOH A O 1 HETATM 5719 O O . HOH H 5 . ? -3.170 54.326 51.393 1.00 44.41 ? 1802 HOH A O 1 HETATM 5720 O O . HOH H 5 . ? 26.036 37.568 47.535 1.00 45.26 ? 1803 HOH A O 1 HETATM 5721 O O . HOH H 5 . ? -5.908 14.606 42.080 1.00 46.55 ? 1804 HOH A O 1 HETATM 5722 O O . HOH H 5 . ? 27.591 37.881 27.002 1.00 44.11 ? 1805 HOH A O 1 HETATM 5723 O O . HOH H 5 . ? 24.670 29.012 12.924 1.00 48.53 ? 1806 HOH A O 1 HETATM 5724 O O . HOH H 5 . ? 25.134 15.607 59.348 1.00 40.06 ? 1807 HOH A O 1 HETATM 5725 O O . HOH H 5 . ? -4.752 31.506 31.081 1.00 40.26 ? 1808 HOH A O 1 HETATM 5726 O O . HOH H 5 . ? 40.923 10.311 43.646 1.00 48.73 ? 1809 HOH A O 1 HETATM 5727 O O . HOH H 5 . ? 17.908 28.149 9.188 1.00 43.24 ? 1810 HOH A O 1 HETATM 5728 O O . HOH H 5 . ? 24.196 33.792 14.367 1.00 43.11 ? 1811 HOH A O 1 HETATM 5729 O O . HOH H 5 . ? 11.205 46.794 41.320 1.00 44.68 ? 1812 HOH A O 1 HETATM 5730 O O . HOH H 5 . ? 44.759 20.633 41.446 1.00 51.01 ? 1813 HOH A O 1 HETATM 5731 O O . HOH H 5 . ? -14.797 17.658 50.809 1.00 51.55 ? 1814 HOH A O 1 HETATM 5732 O O . HOH H 5 . ? 26.859 -3.274 30.030 1.00 52.67 ? 1815 HOH A O 1 HETATM 5733 O O . HOH H 5 . ? -0.867 17.356 62.572 1.00 51.63 ? 1816 HOH A O 1 HETATM 5734 O O . HOH H 5 . ? 3.247 51.678 52.534 1.00 49.24 ? 1817 HOH A O 1 HETATM 5735 O O . HOH H 5 . ? 29.897 36.473 23.690 1.00 38.15 ? 1818 HOH A O 1 HETATM 5736 O O . HOH H 5 . ? -1.010 52.352 64.556 1.00 49.72 ? 1819 HOH A O 1 HETATM 5737 O O . HOH H 5 . ? 6.735 36.190 23.022 1.00 39.63 ? 1820 HOH A O 1 HETATM 5738 O O . HOH H 5 . ? 27.758 38.404 24.373 1.00 42.24 ? 1821 HOH A O 1 HETATM 5739 O O . HOH H 5 . ? -11.610 24.650 40.072 1.00 46.65 ? 1822 HOH A O 1 HETATM 5740 O O . HOH H 5 . ? 1.123 23.152 67.716 1.00 51.81 ? 1823 HOH A O 1 HETATM 5741 O O . HOH H 5 . ? 10.347 1.972 22.399 1.00 51.77 ? 1824 HOH A O 1 HETATM 5742 O O . HOH H 5 . ? 22.969 11.768 64.649 1.00 59.75 ? 1825 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 HIS 1 -3 -3 HIS HIS A . n A 1 2 HIS 2 -2 -2 HIS HIS A . n A 1 3 ALA 3 -1 -1 ALA ALA A . n A 1 4 ALA 4 0 0 ALA ALA A . n A 1 5 ASP 5 1 1 ASP ASP A . n A 1 6 TYR 6 2 2 TYR TYR A . n A 1 7 VAL 7 3 3 VAL VAL A . n A 1 8 LEU 8 4 4 LEU LEU A . n A 1 9 TYR 9 5 5 TYR TYR A . n A 1 10 LYS 10 6 6 LYS LYS A . n A 1 11 ASP 11 7 7 ASP ASP A . n A 1 12 ALA 12 8 8 ALA ALA A . n A 1 13 THR 13 9 9 THR THR A . n A 1 14 LYS 14 10 10 LYS LYS A . n A 1 15 PRO 15 11 11 PRO PRO A . n A 1 16 VAL 16 12 12 VAL VAL A . n A 1 17 GLU 17 13 13 GLU GLU A . n A 1 18 ASP 18 14 14 ASP ASP A . n A 1 19 ARG 19 15 15 ARG ARG A . n A 1 20 VAL 20 16 16 VAL VAL A . n A 1 21 ALA 21 17 17 ALA ALA A . n A 1 22 ASP 22 18 18 ASP ASP A . n A 1 23 LEU 23 19 19 LEU LEU A . n A 1 24 LEU 24 20 20 LEU LEU A . n A 1 25 GLY 25 21 21 GLY GLY A . n A 1 26 ARG 26 22 22 ARG ARG A . n A 1 27 MET 27 23 23 MET MET A . n A 1 28 THR 28 24 24 THR THR A . n A 1 29 LEU 29 25 25 LEU LEU A . n A 1 30 ALA 30 26 26 ALA ALA A . n A 1 31 GLU 31 27 27 GLU GLU A . n A 1 32 LYS 32 28 28 LYS LYS A . n A 1 33 ILE 33 29 29 ILE ILE A . n A 1 34 GLY 34 30 30 GLY GLY A . n A 1 35 GLN 35 31 31 GLN GLN A . n A 1 36 MET 36 32 32 MET MET A . n A 1 37 THR 37 33 33 THR THR A . n A 1 38 GLN 38 34 34 GLN GLN A . n A 1 39 ILE 39 35 35 ILE ILE A . n A 1 40 GLU 40 36 36 GLU GLU A . n A 1 41 ARG 41 37 37 ARG ARG A . n A 1 42 LEU 42 38 38 LEU LEU A . n A 1 43 VAL 43 39 39 VAL VAL A . n A 1 44 ALA 44 40 40 ALA ALA A . n A 1 45 THR 45 41 41 THR THR A . n A 1 46 PRO 46 42 42 PRO PRO A . n A 1 47 ASP 47 43 43 ASP ASP A . n A 1 48 VAL 48 44 44 VAL VAL A . n A 1 49 LEU 49 45 45 LEU LEU A . n A 1 50 ARG 50 46 46 ARG ARG A . n A 1 51 ASP 51 47 47 ASP ASP A . n A 1 52 ASN 52 48 48 ASN ASN A . n A 1 53 PHE 53 49 49 PHE PHE A . n A 1 54 ILE 54 50 50 ILE ILE A . n A 1 55 GLY 55 51 51 GLY GLY A . n A 1 56 SER 56 52 52 SER SER A . n A 1 57 LEU 57 53 53 LEU LEU A . n A 1 58 LEU 58 54 54 LEU LEU A . n A 1 59 SER 59 55 55 SER SER A . n A 1 60 GLY 60 56 56 GLY GLY A . n A 1 61 GLY 61 57 57 GLY GLY A . n A 1 62 GLY 62 58 58 GLY GLY A . n A 1 63 SER 63 59 59 SER SER A . n A 1 64 VAL 64 60 60 VAL VAL A . n A 1 65 PRO 65 61 61 PRO PRO A . n A 1 66 ARG 66 62 62 ARG ARG A . n A 1 67 LYS 67 63 63 LYS LYS A . n A 1 68 GLY 68 64 64 GLY GLY A . n A 1 69 ALA 69 65 65 ALA ALA A . n A 1 70 THR 70 66 66 THR THR A . n A 1 71 ALA 71 67 67 ALA ALA A . n A 1 72 LYS 72 68 68 LYS LYS A . n A 1 73 GLU 73 69 69 GLU GLU A . n A 1 74 TRP 74 70 70 TRP TRP A . n A 1 75 GLN 75 71 71 GLN GLN A . n A 1 76 ASP 76 72 72 ASP ASP A . n A 1 77 MET 77 73 73 MET MET A . n A 1 78 VAL 78 74 74 VAL VAL A . n A 1 79 ASP 79 75 75 ASP ASP A . n A 1 80 GLY 80 76 76 GLY GLY A . n A 1 81 PHE 81 77 77 PHE PHE A . n A 1 82 GLN 82 78 78 GLN GLN A . n A 1 83 LYS 83 79 79 LYS LYS A . n A 1 84 ALA 84 80 80 ALA ALA A . n A 1 85 CYS 85 81 81 CYS CYS A . n A 1 86 MET 86 82 82 MET MET A . n A 1 87 SER 87 83 83 SER SER A . n A 1 88 THR 88 84 84 THR THR A . n A 1 89 ARG 89 85 85 ARG ARG A . n A 1 90 LEU 90 86 86 LEU LEU A . n A 1 91 GLY 91 87 87 GLY GLY A . n A 1 92 ILE 92 88 88 ILE ILE A . n A 1 93 PRO 93 89 89 PRO PRO A . n A 1 94 MET 94 90 90 MET MET A . n A 1 95 ILE 95 91 91 ILE ILE A . n A 1 96 TYR 96 92 92 TYR TYR A . n A 1 97 GLY 97 93 93 GLY GLY A . n A 1 98 ILE 98 94 94 ILE ILE A . n A 1 99 ASP 99 95 95 ASP ASP A . n A 1 100 ALA 100 96 96 ALA ALA A . n A 1 101 VAL 101 97 97 VAL VAL A . n A 1 102 HIS 102 98 98 HIS HIS A . n A 1 103 GLY 103 99 99 GLY GLY A . n A 1 104 GLN 104 100 100 GLN GLN A . n A 1 105 ASN 105 101 101 ASN ASN A . n A 1 106 ASN 106 102 102 ASN ASN A . n A 1 107 VAL 107 103 103 VAL VAL A . n A 1 108 TYR 108 104 104 TYR TYR A . n A 1 109 GLY 109 105 105 GLY GLY A . n A 1 110 ALA 110 106 106 ALA ALA A . n A 1 111 THR 111 107 107 THR THR A . n A 1 112 ILE 112 108 108 ILE ILE A . n A 1 113 PHE 113 109 109 PHE PHE A . n A 1 114 PRO 114 110 110 PRO PRO A . n A 1 115 HIS 115 111 111 HIS HIS A . n A 1 116 ASN 116 112 112 ASN ASN A . n A 1 117 VAL 117 113 113 VAL VAL A . n A 1 118 GLY 118 114 114 GLY GLY A . n A 1 119 LEU 119 115 115 LEU LEU A . n A 1 120 GLY 120 116 116 GLY GLY A . n A 1 121 ALA 121 117 117 ALA ALA A . n A 1 122 THR 122 118 118 THR THR A . n A 1 123 ARG 123 119 119 ARG ARG A . n A 1 124 ASP 124 120 120 ASP ASP A . n A 1 125 PRO 125 121 121 PRO PRO A . n A 1 126 TYR 126 122 122 TYR TYR A . n A 1 127 LEU 127 123 123 LEU LEU A . n A 1 128 VAL 128 124 124 VAL VAL A . n A 1 129 LYS 129 125 125 LYS LYS A . n A 1 130 ARG 130 126 126 ARG ARG A . n A 1 131 ILE 131 127 127 ILE ILE A . n A 1 132 GLY 132 128 128 GLY GLY A . n A 1 133 GLU 133 129 129 GLU GLU A . n A 1 134 ALA 134 130 130 ALA ALA A . n A 1 135 THR 135 131 131 THR THR A . n A 1 136 ALA 136 132 132 ALA ALA A . n A 1 137 LEU 137 133 133 LEU LEU A . n A 1 138 GLU 138 134 134 GLU GLU A . n A 1 139 VAL 139 135 135 VAL VAL A . n A 1 140 ARG 140 136 136 ARG ARG A . n A 1 141 ALA 141 137 137 ALA ALA A . n A 1 142 THR 142 138 138 THR THR A . n A 1 143 GLY 143 139 139 GLY GLY A . n A 1 144 ILE 144 140 140 ILE ILE A . n A 1 145 GLN 145 141 141 GLN GLN A . n A 1 146 TYR 146 142 142 TYR TYR A . n A 1 147 ALA 147 143 143 ALA ALA A . n A 1 148 PHE 148 144 144 PHE PHE A . n A 1 149 ALA 149 145 145 ALA ALA A . n A 1 150 PRO 150 146 146 PRO PRO A . n A 1 151 CYS 151 147 147 CYS CYS A . n A 1 152 ILE 152 148 148 ILE ILE A . n A 1 153 ALA 153 149 149 ALA ALA A . n A 1 154 VAL 154 150 150 VAL VAL A . n A 1 155 CYS 155 151 151 CYS CYS A . n A 1 156 ARG 156 152 152 ARG ARG A . n A 1 157 ASP 157 153 153 ASP ASP A . n A 1 158 PRO 158 154 154 PRO PRO A . n A 1 159 ARG 159 155 155 ARG ARG A . n A 1 160 TRP 160 156 156 TRP TRP A . n A 1 161 GLY 161 157 157 GLY GLY A . n A 1 162 ARG 162 158 158 ARG ARG A . n A 1 163 CYS 163 159 159 CYS CYS A . n A 1 164 TYR 164 160 160 TYR TYR A . n A 1 165 GLU 165 161 161 GLU GLU A . n A 1 166 SER 166 162 162 SER SER A . n A 1 167 TYR 167 163 163 TYR TYR A . n A 1 168 SER 168 164 164 SER SER A . n A 1 169 GLU 169 165 165 GLU GLU A . n A 1 170 ASP 170 166 166 ASP ASP A . n A 1 171 ARG 171 167 167 ARG ARG A . n A 1 172 ARG 172 168 168 ARG ARG A . n A 1 173 ILE 173 169 169 ILE ILE A . n A 1 174 VAL 174 170 170 VAL VAL A . n A 1 175 GLN 175 171 171 GLN GLN A . n A 1 176 SER 176 172 172 SER SER A . n A 1 177 MET 177 173 173 MET MET A . n A 1 178 THR 178 174 174 THR THR A . n A 1 179 GLU 179 175 175 GLU GLU A . n A 1 180 LEU 180 176 176 LEU LEU A . n A 1 181 ILE 181 177 177 ILE ILE A . n A 1 182 PRO 182 178 178 PRO PRO A . n A 1 183 GLY 183 179 179 GLY GLY A . n A 1 184 LEU 184 180 180 LEU LEU A . n A 1 185 GLN 185 181 181 GLN GLN A . n A 1 186 GLY 186 182 182 GLY GLY A . n A 1 187 ASP 187 183 183 ASP ASP A . n A 1 188 VAL 188 184 184 VAL VAL A . n A 1 189 PRO 189 185 185 PRO PRO A . n A 1 190 LYS 190 186 186 LYS LYS A . n A 1 191 ASP 191 187 187 ASP ASP A . n A 1 192 PHE 192 188 188 PHE PHE A . n A 1 193 THR 193 189 189 THR THR A . n A 1 194 SER 194 190 190 SER SER A . n A 1 195 GLY 195 191 191 GLY GLY A . n A 1 196 MET 196 192 192 MET MET A . n A 1 197 PRO 197 193 193 PRO PRO A . n A 1 198 PHE 198 194 194 PHE PHE A . n A 1 199 VAL 199 195 195 VAL VAL A . n A 1 200 ALA 200 196 196 ALA ALA A . n A 1 201 GLY 201 197 197 GLY GLY A . n A 1 202 LYS 202 198 198 LYS LYS A . n A 1 203 ASN 203 199 199 ASN ASN A . n A 1 204 LYS 204 200 200 LYS LYS A . n A 1 205 VAL 205 201 201 VAL VAL A . n A 1 206 ALA 206 202 202 ALA ALA A . n A 1 207 ALA 207 203 203 ALA ALA A . n A 1 208 CYS 208 204 204 CYS CYS A . n A 1 209 ALA 209 205 205 ALA ALA A . n A 1 210 LYS 210 206 206 LYS LYS A . n A 1 211 HIS 211 207 207 HIS HIS A . n A 1 212 PHE 212 208 208 PHE PHE A . n A 1 213 VAL 213 209 209 VAL VAL A . n A 1 214 GLY 214 210 210 GLY GLY A . n A 1 215 ASP 215 211 211 ASP ASP A . n A 1 216 GLY 216 212 212 GLY GLY A . n A 1 217 GLY 217 213 213 GLY GLY A . n A 1 218 THR 218 214 214 THR THR A . n A 1 219 VAL 219 215 215 VAL VAL A . n A 1 220 ASP 220 216 216 ASP ASP A . n A 1 221 GLY 221 217 217 GLY GLY A . n A 1 222 ILE 222 218 218 ILE ILE A . n A 1 223 ASN 223 219 219 ASN ASN A . n A 1 224 GLU 224 220 220 GLU GLU A . n A 1 225 ASN 225 221 221 ASN ASN A . n A 1 226 ASN 226 222 222 ASN ASN A . n A 1 227 THR 227 223 223 THR THR A . n A 1 228 ILE 228 224 224 ILE ILE A . n A 1 229 ILE 229 225 225 ILE ILE A . n A 1 230 ASN 230 226 226 ASN ASN A . n A 1 231 ARG 231 227 227 ARG ARG A . n A 1 232 GLU 232 228 228 GLU GLU A . n A 1 233 GLY 233 229 229 GLY GLY A . n A 1 234 LEU 234 230 230 LEU LEU A . n A 1 235 MET 235 231 231 MET MET A . n A 1 236 ASN 236 232 232 ASN ASN A . n A 1 237 ILE 237 233 233 ILE ILE A . n A 1 238 HIS 238 234 234 HIS HIS A . n A 1 239 MET 239 235 235 MET MET A . n A 1 240 PRO 240 236 236 PRO PRO A . n A 1 241 ALA 241 237 237 ALA ALA A . n A 1 242 TYR 242 238 238 TYR TYR A . n A 1 243 LYS 243 239 239 LYS LYS A . n A 1 244 ASN 244 240 240 ASN ASN A . n A 1 245 ALA 245 241 241 ALA ALA A . n A 1 246 MET 246 242 242 MET MET A . n A 1 247 ASP 247 243 243 ASP ASP A . n A 1 248 LYS 248 244 244 LYS LYS A . n A 1 249 GLY 249 245 245 GLY GLY A . n A 1 250 VAL 250 246 246 VAL VAL A . n A 1 251 SER 251 247 247 SER SER A . n A 1 252 THR 252 248 248 THR THR A . n A 1 253 VAL 253 249 249 VAL VAL A . n A 1 254 MET 254 250 250 MET MET A . n A 1 255 ILE 255 251 251 ILE ILE A . n A 1 256 SER 256 252 252 SER SER A . n A 1 257 TYR 257 253 253 TYR TYR A . n A 1 258 SER 258 254 254 SER SER A . n A 1 259 SER 259 255 255 SER SER A . n A 1 260 TRP 260 256 256 TRP TRP A . n A 1 261 ASN 261 257 257 ASN ASN A . n A 1 262 GLY 262 258 258 GLY GLY A . n A 1 263 VAL 263 259 259 VAL VAL A . n A 1 264 LYS 264 260 260 LYS LYS A . n A 1 265 MET 265 261 261 MET MET A . n A 1 266 HIS 266 262 262 HIS HIS A . n A 1 267 ALA 267 263 263 ALA ALA A . n A 1 268 ASN 268 264 264 ASN ASN A . n A 1 269 GLN 269 265 265 GLN GLN A . n A 1 270 ASP 270 266 266 ASP ASP A . n A 1 271 LEU 271 267 267 LEU LEU A . n A 1 272 VAL 272 268 268 VAL VAL A . n A 1 273 THR 273 269 269 THR THR A . n A 1 274 GLY 274 270 270 GLY GLY A . n A 1 275 TYR 275 271 271 TYR TYR A . n A 1 276 LEU 276 272 272 LEU LEU A . n A 1 277 LYS 277 273 273 LYS LYS A . n A 1 278 ASP 278 274 274 ASP ASP A . n A 1 279 THR 279 275 275 THR THR A . n A 1 280 LEU 280 276 276 LEU LEU A . n A 1 281 LYS 281 277 277 LYS LYS A . n A 1 282 PHE 282 278 278 PHE PHE A . n A 1 283 LYS 283 279 279 LYS LYS A . n A 1 284 GLY 284 280 280 GLY GLY A . n A 1 285 PHE 285 281 281 PHE PHE A . n A 1 286 VAL 286 282 282 VAL VAL A . n A 1 287 ILE 287 283 283 ILE ILE A . n A 1 288 SER 288 284 284 SER SER A . n A 1 289 ASP 289 285 285 ASP ASP A . n A 1 290 TRP 290 286 286 TRP TRP A . n A 1 291 GLU 291 287 287 GLU GLU A . n A 1 292 GLY 292 288 288 GLY GLY A . n A 1 293 ILE 293 289 289 ILE ILE A . n A 1 294 ASP 294 290 290 ASP ASP A . n A 1 295 ARG 295 291 291 ARG ARG A . n A 1 296 ILE 296 292 292 ILE ILE A . n A 1 297 THR 297 293 293 THR THR A . n A 1 298 THR 298 294 294 THR THR A . n A 1 299 PRO 299 295 295 PRO PRO A . n A 1 300 ALA 300 296 296 ALA ALA A . n A 1 301 GLY 301 297 297 GLY GLY A . n A 1 302 SER 302 298 298 SER SER A . n A 1 303 ASP 303 299 299 ASP ASP A . n A 1 304 TYR 304 300 300 TYR TYR A . n A 1 305 SER 305 301 301 SER SER A . n A 1 306 TYR 306 302 302 TYR TYR A . n A 1 307 SER 307 303 303 SER SER A . n A 1 308 VAL 308 304 304 VAL VAL A . n A 1 309 LYS 309 305 305 LYS LYS A . n A 1 310 ALA 310 306 306 ALA ALA A . n A 1 311 SER 311 307 307 SER SER A . n A 1 312 ILE 312 308 308 ILE ILE A . n A 1 313 LEU 313 309 309 LEU LEU A . n A 1 314 ALA 314 310 310 ALA ALA A . n A 1 315 GLY 315 311 311 GLY GLY A . n A 1 316 LEU 316 312 312 LEU LEU A . n A 1 317 ASP 317 313 313 ASP ASP A . n A 1 318 MET 318 314 314 MET MET A . n A 1 319 ILE 319 315 315 ILE ILE A . n A 1 320 MET 320 316 316 MET MET A . n A 1 321 VAL 321 317 317 VAL VAL A . n A 1 322 PRO 322 318 318 PRO PRO A . n A 1 323 ASN 323 319 319 ASN ASN A . n A 1 324 LYS 324 320 320 LYS LYS A . n A 1 325 TYR 325 321 321 TYR TYR A . n A 1 326 GLN 326 322 322 GLN GLN A . n A 1 327 GLN 327 323 323 GLN GLN A . n A 1 328 PHE 328 324 324 PHE PHE A . n A 1 329 ILE 329 325 325 ILE ILE A . n A 1 330 SER 330 326 326 SER SER A . n A 1 331 ILE 331 327 327 ILE ILE A . n A 1 332 LEU 332 328 328 LEU LEU A . n A 1 333 THR 333 329 329 THR THR A . n A 1 334 GLY 334 330 330 GLY GLY A . n A 1 335 HIS 335 331 331 HIS HIS A . n A 1 336 VAL 336 332 332 VAL VAL A . n A 1 337 ASN 337 333 333 ASN ASN A . n A 1 338 GLY 338 334 334 GLY GLY A . n A 1 339 GLY 339 335 335 GLY GLY A . n A 1 340 VAL 340 336 336 VAL VAL A . n A 1 341 ILE 341 337 337 ILE ILE A . n A 1 342 PRO 342 338 338 PRO PRO A . n A 1 343 MET 343 339 339 MET MET A . n A 1 344 SER 344 340 340 SER SER A . n A 1 345 ARG 345 341 341 ARG ARG A . n A 1 346 ILE 346 342 342 ILE ILE A . n A 1 347 ASP 347 343 343 ASP ASP A . n A 1 348 ASP 348 344 344 ASP ASP A . n A 1 349 ALA 349 345 345 ALA ALA A . n A 1 350 VAL 350 346 346 VAL VAL A . n A 1 351 THR 351 347 347 THR THR A . n A 1 352 ARG 352 348 348 ARG ARG A . n A 1 353 ILE 353 349 349 ILE ILE A . n A 1 354 LEU 354 350 350 LEU LEU A . n A 1 355 ARG 355 351 351 ARG ARG A . n A 1 356 VAL 356 352 352 VAL VAL A . n A 1 357 LYS 357 353 353 LYS LYS A . n A 1 358 PHE 358 354 354 PHE PHE A . n A 1 359 THR 359 355 355 THR THR A . n A 1 360 MET 360 356 356 MET MET A . n A 1 361 GLY 361 357 357 GLY GLY A . n A 1 362 LEU 362 358 358 LEU LEU A . n A 1 363 PHE 363 359 359 PHE PHE A . n A 1 364 GLU 364 360 360 GLU GLU A . n A 1 365 ASN 365 361 361 ASN ASN A . n A 1 366 PRO 366 362 362 PRO PRO A . n A 1 367 TYR 367 363 363 TYR TYR A . n A 1 368 ALA 368 364 364 ALA ALA A . n A 1 369 ASP 369 365 365 ASP ASP A . n A 1 370 PRO 370 366 366 PRO PRO A . n A 1 371 ALA 371 367 367 ALA ALA A . n A 1 372 MET 372 368 368 MET MET A . n A 1 373 ALA 373 369 369 ALA ALA A . n A 1 374 GLU 374 370 370 GLU GLU A . n A 1 375 GLN 375 371 371 GLN GLN A . n A 1 376 LEU 376 372 372 LEU LEU A . n A 1 377 GLY 377 373 373 GLY GLY A . n A 1 378 LYS 378 374 374 LYS LYS A . n A 1 379 GLN 379 375 375 GLN GLN A . n A 1 380 GLU 380 376 376 GLU GLU A . n A 1 381 HIS 381 377 377 HIS HIS A . n A 1 382 ARG 382 378 378 ARG ARG A . n A 1 383 ASP 383 379 379 ASP ASP A . n A 1 384 LEU 384 380 380 LEU LEU A . n A 1 385 ALA 385 381 381 ALA ALA A . n A 1 386 ARG 386 382 382 ARG ARG A . n A 1 387 GLU 387 383 383 GLU GLU A . n A 1 388 ALA 388 384 384 ALA ALA A . n A 1 389 ALA 389 385 385 ALA ALA A . n A 1 390 ARG 390 386 386 ARG ARG A . n A 1 391 LYS 391 387 387 LYS LYS A . n A 1 392 SER 392 388 388 SER SER A . n A 1 393 LEU 393 389 389 LEU LEU A . n A 1 394 VAL 394 390 390 VAL VAL A . n A 1 395 LEU 395 391 391 LEU LEU A . n A 1 396 LEU 396 392 392 LEU LEU A . n A 1 397 LYS 397 393 393 LYS LYS A . n A 1 398 ASN 398 394 394 ASN ASN A . n A 1 399 GLY 399 395 395 GLY GLY A . n A 1 400 LYS 400 396 396 LYS LYS A . n A 1 401 THR 401 397 397 THR THR A . n A 1 402 SER 402 398 398 SER SER A . n A 1 403 THR 403 399 399 THR THR A . n A 1 404 ASP 404 400 400 ASP ASP A . n A 1 405 ALA 405 401 401 ALA ALA A . n A 1 406 PRO 406 402 402 PRO PRO A . n A 1 407 LEU 407 403 403 LEU LEU A . n A 1 408 LEU 408 404 404 LEU LEU A . n A 1 409 PRO 409 405 405 PRO PRO A . n A 1 410 LEU 410 406 406 LEU LEU A . n A 1 411 PRO 411 407 407 PRO PRO A . n A 1 412 LYS 412 408 408 LYS LYS A . n A 1 413 LYS 413 409 409 LYS LYS A . n A 1 414 ALA 414 410 410 ALA ALA A . n A 1 415 PRO 415 411 411 PRO PRO A . n A 1 416 LYS 416 412 412 LYS LYS A . n A 1 417 ILE 417 413 413 ILE ILE A . n A 1 418 LEU 418 414 414 LEU LEU A . n A 1 419 VAL 419 415 415 VAL VAL A . n A 1 420 ALA 420 416 416 ALA ALA A . n A 1 421 GLY 421 417 417 GLY GLY A . n A 1 422 SER 422 418 418 SER SER A . n A 1 423 HIS 423 419 419 HIS HIS A . n A 1 424 ALA 424 420 420 ALA ALA A . n A 1 425 ASP 425 421 421 ASP ASP A . n A 1 426 ASN 426 422 422 ASN ASN A . n A 1 427 LEU 427 423 423 LEU LEU A . n A 1 428 GLY 428 424 424 GLY GLY A . n A 1 429 TYR 429 425 425 TYR TYR A . n A 1 430 GLN 430 426 426 GLN GLN A . n A 1 431 CYS 431 427 427 CYS CYS A . n A 1 432 GLY 432 428 428 GLY GLY A . n A 1 433 GLY 433 429 429 GLY GLY A . n A 1 434 TRP 434 430 430 TRP TRP A . n A 1 435 THR 435 431 431 THR THR A . n A 1 436 ILE 436 432 432 ILE ILE A . n A 1 437 GLU 437 433 433 GLU GLU A . n A 1 438 TRP 438 434 434 TRP TRP A . n A 1 439 GLN 439 435 435 GLN GLN A . n A 1 440 GLY 440 436 436 GLY GLY A . n A 1 441 ASP 441 437 437 ASP ASP A . n A 1 442 THR 442 438 438 THR THR A . n A 1 443 GLY 443 439 439 GLY GLY A . n A 1 444 ARG 444 440 440 ARG ARG A . n A 1 445 THR 445 441 441 THR THR A . n A 1 446 THR 446 442 442 THR THR A . n A 1 447 VAL 447 443 443 VAL VAL A . n A 1 448 GLY 448 444 444 GLY GLY A . n A 1 449 THR 449 445 445 THR THR A . n A 1 450 THR 450 446 446 THR THR A . n A 1 451 ILE 451 447 447 ILE ILE A . n A 1 452 LEU 452 448 448 LEU LEU A . n A 1 453 GLU 453 449 449 GLU GLU A . n A 1 454 ALA 454 450 450 ALA ALA A . n A 1 455 VAL 455 451 451 VAL VAL A . n A 1 456 LYS 456 452 452 LYS LYS A . n A 1 457 ALA 457 453 453 ALA ALA A . n A 1 458 ALA 458 454 454 ALA ALA A . n A 1 459 VAL 459 455 455 VAL VAL A . n A 1 460 ASP 460 456 456 ASP ASP A . n A 1 461 PRO 461 457 457 PRO PRO A . n A 1 462 SER 462 458 458 SER SER A . n A 1 463 THR 463 459 459 THR THR A . n A 1 464 VAL 464 460 460 VAL VAL A . n A 1 465 VAL 465 461 461 VAL VAL A . n A 1 466 VAL 466 462 462 VAL VAL A . n A 1 467 PHE 467 463 463 PHE PHE A . n A 1 468 ALA 468 464 464 ALA ALA A . n A 1 469 GLU 469 465 465 GLU GLU A . n A 1 470 ASN 470 466 466 ASN ASN A . n A 1 471 PRO 471 467 467 PRO PRO A . n A 1 472 ASP 472 468 468 ASP ASP A . n A 1 473 ALA 473 469 469 ALA ALA A . n A 1 474 GLU 474 470 470 GLU GLU A . n A 1 475 PHE 475 471 471 PHE PHE A . n A 1 476 VAL 476 472 472 VAL VAL A . n A 1 477 LYS 477 473 473 LYS LYS A . n A 1 478 SER 478 474 474 SER SER A . n A 1 479 GLY 479 475 475 GLY GLY A . n A 1 480 GLY 480 476 476 GLY GLY A . n A 1 481 PHE 481 477 477 PHE PHE A . n A 1 482 SER 482 478 478 SER SER A . n A 1 483 TYR 483 479 479 TYR TYR A . n A 1 484 ALA 484 480 480 ALA ALA A . n A 1 485 ILE 485 481 481 ILE ILE A . n A 1 486 VAL 486 482 482 VAL VAL A . n A 1 487 ALA 487 483 483 ALA ALA A . n A 1 488 VAL 488 484 484 VAL VAL A . n A 1 489 GLY 489 485 485 GLY GLY A . n A 1 490 GLU 490 486 486 GLU GLU A . n A 1 491 HIS 491 487 487 HIS HIS A . n A 1 492 PRO 492 488 488 PRO PRO A . n A 1 493 TYR 493 489 489 TYR TYR A . n A 1 494 THR 494 490 490 THR THR A . n A 1 495 GLU 495 491 491 GLU GLU A . n A 1 496 THR 496 492 492 THR THR A . n A 1 497 LYS 497 493 493 LYS LYS A . n A 1 498 GLY 498 494 494 GLY GLY A . n A 1 499 ASP 499 495 495 ASP ASP A . n A 1 500 ASN 500 496 496 ASN ASN A . n A 1 501 LEU 501 497 497 LEU LEU A . n A 1 502 ASN 502 498 498 ASN ASN A . n A 1 503 LEU 503 499 499 LEU LEU A . n A 1 504 THR 504 500 500 THR THR A . n A 1 505 ILE 505 501 501 ILE ILE A . n A 1 506 PRO 506 502 502 PRO PRO A . n A 1 507 GLU 507 503 503 GLU GLU A . n A 1 508 PRO 508 504 504 PRO PRO A . n A 1 509 GLY 509 505 505 GLY GLY A . n A 1 510 LEU 510 506 506 LEU LEU A . n A 1 511 SER 511 507 507 SER SER A . n A 1 512 THR 512 508 508 THR THR A . n A 1 513 VAL 513 509 509 VAL VAL A . n A 1 514 GLN 514 510 510 GLN GLN A . n A 1 515 ALA 515 511 511 ALA ALA A . n A 1 516 VAL 516 512 512 VAL VAL A . n A 1 517 CYS 517 513 513 CYS CYS A . n A 1 518 GLY 518 514 514 GLY GLY A . n A 1 519 GLY 519 515 515 GLY GLY A . n A 1 520 VAL 520 516 516 VAL VAL A . n A 1 521 ARG 521 517 517 ARG ARG A . n A 1 522 CYS 522 518 518 CYS CYS A . n A 1 523 ALA 523 519 519 ALA ALA A . n A 1 524 THR 524 520 520 THR THR A . n A 1 525 VAL 525 521 521 VAL VAL A . n A 1 526 LEU 526 522 522 LEU LEU A . n A 1 527 ILE 527 523 523 ILE ILE A . n A 1 528 SER 528 524 524 SER SER A . n A 1 529 GLY 529 525 525 GLY GLY A . n A 1 530 ARG 530 526 526 ARG ARG A . n A 1 531 PRO 531 527 527 PRO PRO A . n A 1 532 VAL 532 528 528 VAL VAL A . n A 1 533 VAL 533 529 529 VAL VAL A . n A 1 534 VAL 534 530 530 VAL VAL A . n A 1 535 GLN 535 531 531 GLN GLN A . n A 1 536 PRO 536 532 532 PRO PRO A . n A 1 537 LEU 537 533 533 LEU LEU A . n A 1 538 LEU 538 534 534 LEU LEU A . n A 1 539 ALA 539 535 535 ALA ALA A . n A 1 540 ALA 540 536 536 ALA ALA A . n A 1 541 SER 541 537 537 SER SER A . n A 1 542 ASP 542 538 538 ASP ASP A . n A 1 543 ALA 543 539 539 ALA ALA A . n A 1 544 LEU 544 540 540 LEU LEU A . n A 1 545 VAL 545 541 541 VAL VAL A . n A 1 546 ALA 546 542 542 ALA ALA A . n A 1 547 ALA 547 543 543 ALA ALA A . n A 1 548 TRP 548 544 544 TRP TRP A . n A 1 549 LEU 549 545 545 LEU LEU A . n A 1 550 PRO 550 546 546 PRO PRO A . n A 1 551 GLY 551 547 547 GLY GLY A . n A 1 552 SER 552 548 548 SER SER A . n A 1 553 GLU 553 549 549 GLU GLU A . n A 1 554 GLY 554 550 550 GLY GLY A . n A 1 555 GLN 555 551 551 GLN GLN A . n A 1 556 GLY 556 552 552 GLY GLY A . n A 1 557 VAL 557 553 553 VAL VAL A . n A 1 558 THR 558 554 554 THR THR A . n A 1 559 ASP 559 555 555 ASP ASP A . n A 1 560 ALA 560 556 556 ALA ALA A . n A 1 561 LEU 561 557 557 LEU LEU A . n A 1 562 PHE 562 558 558 PHE PHE A . n A 1 563 GLY 563 559 559 GLY GLY A . n A 1 564 ASP 564 560 560 ASP ASP A . n A 1 565 PHE 565 561 561 PHE PHE A . n A 1 566 GLY 566 562 562 GLY GLY A . n A 1 567 PHE 567 563 563 PHE PHE A . n A 1 568 THR 568 564 564 THR THR A . n A 1 569 GLY 569 565 565 GLY GLY A . n A 1 570 ARG 570 566 566 ARG ARG A . n A 1 571 LEU 571 567 567 LEU LEU A . n A 1 572 PRO 572 568 568 PRO PRO A . n A 1 573 ARG 573 569 569 ARG ARG A . n A 1 574 THR 574 570 570 THR THR A . n A 1 575 TRP 575 571 571 TRP TRP A . n A 1 576 PHE 576 572 572 PHE PHE A . n A 1 577 LYS 577 573 573 LYS LYS A . n A 1 578 SER 578 574 574 SER SER A . n A 1 579 VAL 579 575 575 VAL VAL A . n A 1 580 ASP 580 576 576 ASP ASP A . n A 1 581 GLN 581 577 577 GLN GLN A . n A 1 582 LEU 582 578 578 LEU LEU A . n A 1 583 PRO 583 579 579 PRO PRO A . n A 1 584 MET 584 580 580 MET MET A . n A 1 585 ASN 585 581 581 ASN ASN A . n A 1 586 VAL 586 582 582 VAL VAL A . n A 1 587 GLY 587 583 583 GLY GLY A . n A 1 588 ASP 588 584 584 ASP ASP A . n A 1 589 ALA 589 585 585 ALA ALA A . n A 1 590 HIS 590 586 586 HIS HIS A . n A 1 591 TYR 591 587 587 TYR TYR A . n A 1 592 ASP 592 588 588 ASP ASP A . n A 1 593 PRO 593 589 589 PRO PRO A . n A 1 594 LEU 594 590 590 LEU LEU A . n A 1 595 PHE 595 591 591 PHE PHE A . n A 1 596 ARG 596 592 592 ARG ARG A . n A 1 597 LEU 597 593 593 LEU LEU A . n A 1 598 GLY 598 594 594 GLY GLY A . n A 1 599 TYR 599 595 595 TYR TYR A . n A 1 600 GLY 600 596 596 GLY GLY A . n A 1 601 LEU 601 597 597 LEU LEU A . n A 1 602 THR 602 598 598 THR THR A . n A 1 603 THR 603 599 599 THR THR A . n A 1 604 ASN 604 600 600 ASN ASN A . n A 1 605 ALA 605 601 601 ALA ALA A . n A 1 606 THR 606 602 602 THR THR A . n A 1 607 LYS 607 603 ? ? ? A . n A 1 608 LYS 608 604 ? ? ? A . n A 1 609 TYR 609 605 ? ? ? A . n # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 225 A ASN 221 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 502 A ASN 498 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 604 A ASN 600 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # _pdbx_audit_revision_history.ordinal 1 _pdbx_audit_revision_history.data_content_type 'Structure model' _pdbx_audit_revision_history.major_revision 1 _pdbx_audit_revision_history.minor_revision 0 _pdbx_audit_revision_history.revision_date 2015-03-25 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal ADSC 'data collection' Quantum ? 1 MOLREP phasing . ? 2 REFMAC refinement 5.5.0109 ? 3 HKL-2000 'data reduction' . ? 4 HKL-2000 'data scaling' . ? 5 # _pdbx_entry_details.nonpolymer_details ? _pdbx_entry_details.sequence_details ;THE AUTHORS STATE THERE IS AN ERROR IN THE CDNA SEQUENCING OF AF102868 (GENBANK ACCESSION NUMBER). RESIDUE 320 (SEQUENCE DATABASE RESIDUE 345) IS LYS AND IS NOT ASN. ; _pdbx_entry_details.compound_details ? _pdbx_entry_details.source_details ? _pdbx_entry_details.entry_id 3WLO # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 O A HOH 803 ? ? O A HOH 807 ? ? 1.77 2 1 OD1 A ASN 498 ? ? O A HOH 872 ? ? 1.82 3 1 NH1 A ARG 291 ? B O A HOH 980 ? ? 1.82 4 1 NH2 A ARG 566 ? B O A HOH 995 ? ? 1.89 5 1 ND2 A ASN 466 ? A OG1 A THR 508 ? ? 1.92 6 1 O6 A BGC 705 ? A O A HOH 801 ? ? 1.99 7 1 O A HOH 836 ? ? O A HOH 1405 ? ? 2.00 8 1 NH1 A ARG 227 ? ? O A HOH 840 ? ? 2.02 9 1 O A HOH 1433 ? ? O A HOH 1538 ? ? 2.04 10 1 O A HOH 868 ? ? O A HOH 1316 ? ? 2.04 11 1 O A HOH 816 ? ? O A HOH 901 ? ? 2.05 12 1 NE A ARG 227 ? ? O A HOH 1539 ? ? 2.07 13 1 O A HOH 859 ? ? O A HOH 1257 ? ? 2.08 14 1 O A HOH 950 ? ? O A HOH 1641 ? ? 2.09 15 1 O A HOH 1641 ? ? O A HOH 1679 ? ? 2.12 16 1 O A HOH 857 ? ? O A HOH 995 ? ? 2.14 17 1 O A HOH 1545 ? ? O A HOH 1584 ? ? 2.17 18 1 O A HOH 929 ? ? O A HOH 1252 ? ? 2.17 19 1 O A HOH 1005 ? ? O A HOH 1665 ? ? 2.18 20 1 O A HOH 880 ? ? O A HOH 1433 ? ? 2.18 21 1 O A HOH 949 ? ? O A HOH 1445 ? ? 2.18 22 1 OD1 A ASN 333 ? ? O A HOH 1462 ? ? 2.19 # loop_ _pdbx_validate_symm_contact.id _pdbx_validate_symm_contact.PDB_model_num _pdbx_validate_symm_contact.auth_atom_id_1 _pdbx_validate_symm_contact.auth_asym_id_1 _pdbx_validate_symm_contact.auth_comp_id_1 _pdbx_validate_symm_contact.auth_seq_id_1 _pdbx_validate_symm_contact.PDB_ins_code_1 _pdbx_validate_symm_contact.label_alt_id_1 _pdbx_validate_symm_contact.site_symmetry_1 _pdbx_validate_symm_contact.auth_atom_id_2 _pdbx_validate_symm_contact.auth_asym_id_2 _pdbx_validate_symm_contact.auth_comp_id_2 _pdbx_validate_symm_contact.auth_seq_id_2 _pdbx_validate_symm_contact.PDB_ins_code_2 _pdbx_validate_symm_contact.label_alt_id_2 _pdbx_validate_symm_contact.site_symmetry_2 _pdbx_validate_symm_contact.dist 1 1 O A HOH 929 ? ? 1_555 O A HOH 1092 ? ? 6_555 1.13 2 1 O A HOH 900 ? ? 1_555 O A HOH 1301 ? ? 4_455 1.54 3 1 O A HOH 877 ? ? 1_555 O A HOH 1726 ? ? 6_555 1.57 4 1 O A HOH 829 ? ? 1_555 O A HOH 1262 ? ? 4_455 1.61 5 1 O A HOH 834 ? ? 1_555 O A HOH 1697 ? ? 4_455 1.61 6 1 O A HOH 949 ? ? 1_555 O A HOH 1769 ? ? 4_455 1.80 # _pdbx_validate_rmsd_bond.id 1 _pdbx_validate_rmsd_bond.PDB_model_num 1 _pdbx_validate_rmsd_bond.auth_atom_id_1 CD _pdbx_validate_rmsd_bond.auth_asym_id_1 A _pdbx_validate_rmsd_bond.auth_comp_id_1 GLU _pdbx_validate_rmsd_bond.auth_seq_id_1 503 _pdbx_validate_rmsd_bond.PDB_ins_code_1 ? _pdbx_validate_rmsd_bond.label_alt_id_1 ? _pdbx_validate_rmsd_bond.auth_atom_id_2 OE2 _pdbx_validate_rmsd_bond.auth_asym_id_2 A _pdbx_validate_rmsd_bond.auth_comp_id_2 GLU _pdbx_validate_rmsd_bond.auth_seq_id_2 503 _pdbx_validate_rmsd_bond.PDB_ins_code_2 ? _pdbx_validate_rmsd_bond.label_alt_id_2 ? _pdbx_validate_rmsd_bond.bond_value 1.333 _pdbx_validate_rmsd_bond.bond_target_value 1.252 _pdbx_validate_rmsd_bond.bond_deviation 0.081 _pdbx_validate_rmsd_bond.bond_standard_deviation 0.011 _pdbx_validate_rmsd_bond.linker_flag N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 NE A ARG 62 ? ? CZ A ARG 62 ? ? NH2 A ARG 62 ? ? 116.84 120.30 -3.46 0.50 N 2 1 NE A ARG 126 ? ? CZ A ARG 126 ? ? NH1 A ARG 126 ? ? 127.52 120.30 7.22 0.50 N 3 1 NE A ARG 126 ? ? CZ A ARG 126 ? ? NH2 A ARG 126 ? ? 111.95 120.30 -8.35 0.50 N 4 1 NE A ARG 152 ? ? CZ A ARG 152 ? ? NH1 A ARG 152 ? ? 117.28 120.30 -3.02 0.50 N 5 1 CB A ASP 211 ? ? CG A ASP 211 ? ? OD1 A ASP 211 ? ? 123.81 118.30 5.51 0.90 N 6 1 CB A TYR 425 ? ? CG A TYR 425 ? ? CD2 A TYR 425 ? ? 117.07 121.00 -3.93 0.60 N 7 1 NE A ARG 440 ? ? CZ A ARG 440 ? ? NH1 A ARG 440 ? ? 123.64 120.30 3.34 0.50 N 8 1 NE A ARG 440 ? ? CZ A ARG 440 ? ? NH2 A ARG 440 ? ? 115.38 120.30 -4.92 0.50 N 9 1 CB A ASP 468 ? ? CG A ASP 468 ? ? OD2 A ASP 468 ? ? 123.87 118.30 5.57 0.90 N 10 1 NE A ARG 517 ? ? CZ A ARG 517 ? ? NH1 A ARG 517 ? ? 116.86 120.30 -3.44 0.50 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 HIS A -2 ? ? 145.34 -95.90 2 1 ALA A -1 ? ? -47.42 154.00 3 1 HIS A 98 ? ? -153.34 64.61 4 1 ASN A 221 ? ? -93.39 -154.98 5 1 TYR A 271 ? ? -100.15 -62.12 6 1 ILE A 432 ? ? 70.71 -56.00 7 1 GLU A 491 ? ? 56.05 -134.98 8 1 ARG A 526 ? ? 178.72 165.00 9 1 TRP A 544 ? ? 52.82 -133.73 10 1 GLU A 549 ? ? -104.98 79.76 11 1 VAL A 582 ? ? -59.82 109.04 12 1 TYR A 587 ? ? -63.70 94.64 # _pdbx_validate_peptide_omega.id 1 _pdbx_validate_peptide_omega.PDB_model_num 1 _pdbx_validate_peptide_omega.auth_comp_id_1 HIS _pdbx_validate_peptide_omega.auth_asym_id_1 A _pdbx_validate_peptide_omega.auth_seq_id_1 -3 _pdbx_validate_peptide_omega.PDB_ins_code_1 ? _pdbx_validate_peptide_omega.label_alt_id_1 ? _pdbx_validate_peptide_omega.auth_comp_id_2 HIS _pdbx_validate_peptide_omega.auth_asym_id_2 A _pdbx_validate_peptide_omega.auth_seq_id_2 -2 _pdbx_validate_peptide_omega.PDB_ins_code_2 ? _pdbx_validate_peptide_omega.label_alt_id_2 ? _pdbx_validate_peptide_omega.omega 144.14 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A LYS 603 ? A LYS 607 2 1 Y 1 A LYS 604 ? A LYS 608 3 1 Y 1 A TYR 605 ? A TYR 609 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 BETA-D-GLUCOSE BGC 4 'SULFATE ION' SO4 5 water HOH # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 701 2211 NAG NAG A . C 2 NAG 1 702 4981 NAG NAG A . D 2 NAG 1 703 6001 NAG NAG A . E 3 BGC 1 704 624 BGC GLC A . F 3 BGC 1 705 625 BGC GLC A . G 4 SO4 1 706 1 SO4 SO4 A . H 5 HOH 1 801 1 HOH HOH A . H 5 HOH 2 802 2 HOH HOH A . H 5 HOH 3 803 3 HOH HOH A . H 5 HOH 4 804 4 HOH HOH A . H 5 HOH 5 805 5 HOH HOH A . H 5 HOH 6 806 6 HOH HOH A . H 5 HOH 7 807 7 HOH HOH A . H 5 HOH 8 808 8 HOH HOH A . H 5 HOH 9 809 9 HOH HOH A . H 5 HOH 10 810 10 HOH HOH A . H 5 HOH 11 811 11 HOH HOH A . H 5 HOH 12 812 12 HOH HOH A . H 5 HOH 13 813 13 HOH HOH A . H 5 HOH 14 814 14 HOH HOH A . H 5 HOH 15 815 15 HOH HOH A . H 5 HOH 16 816 16 HOH HOH A . H 5 HOH 17 817 17 HOH HOH A . H 5 HOH 18 818 18 HOH HOH A . H 5 HOH 19 819 19 HOH HOH A . H 5 HOH 20 820 20 HOH HOH A . H 5 HOH 21 821 21 HOH HOH A . H 5 HOH 22 822 22 HOH HOH A . H 5 HOH 23 823 23 HOH HOH A . H 5 HOH 24 824 24 HOH HOH A . H 5 HOH 25 825 25 HOH HOH A . H 5 HOH 26 826 26 HOH HOH A . H 5 HOH 27 827 27 HOH HOH A . H 5 HOH 28 828 28 HOH HOH A . H 5 HOH 29 829 29 HOH HOH A . H 5 HOH 30 830 30 HOH HOH A . H 5 HOH 31 831 31 HOH HOH A . H 5 HOH 32 832 32 HOH HOH A . H 5 HOH 33 833 33 HOH HOH A . H 5 HOH 34 834 34 HOH HOH A . H 5 HOH 35 835 35 HOH HOH A . H 5 HOH 36 836 36 HOH HOH A . H 5 HOH 37 837 37 HOH HOH A . H 5 HOH 38 838 38 HOH HOH A . H 5 HOH 39 839 39 HOH HOH A . H 5 HOH 40 840 40 HOH HOH A . H 5 HOH 41 841 41 HOH HOH A . H 5 HOH 42 842 42 HOH HOH A . H 5 HOH 43 843 43 HOH HOH A . H 5 HOH 44 844 44 HOH HOH A . H 5 HOH 45 845 45 HOH HOH A . H 5 HOH 46 846 46 HOH HOH A . H 5 HOH 47 847 47 HOH HOH A . H 5 HOH 48 848 48 HOH HOH A . H 5 HOH 49 849 49 HOH HOH A . H 5 HOH 50 850 50 HOH HOH A . H 5 HOH 51 851 51 HOH HOH A . H 5 HOH 52 852 52 HOH HOH A . H 5 HOH 53 853 53 HOH HOH A . H 5 HOH 54 854 54 HOH HOH A . H 5 HOH 55 855 55 HOH HOH A . H 5 HOH 56 856 56 HOH HOH A . H 5 HOH 57 857 57 HOH HOH A . H 5 HOH 58 858 58 HOH HOH A . H 5 HOH 59 859 59 HOH HOH A . H 5 HOH 60 860 60 HOH HOH A . H 5 HOH 61 861 61 HOH HOH A . H 5 HOH 62 862 62 HOH HOH A . H 5 HOH 63 863 63 HOH HOH A . H 5 HOH 64 864 64 HOH HOH A . H 5 HOH 65 865 65 HOH HOH A . H 5 HOH 66 866 66 HOH HOH A . H 5 HOH 67 867 67 HOH HOH A . H 5 HOH 68 868 68 HOH HOH A . H 5 HOH 69 869 69 HOH HOH A . H 5 HOH 70 870 70 HOH HOH A . H 5 HOH 71 871 71 HOH HOH A . H 5 HOH 72 872 72 HOH HOH A . H 5 HOH 73 873 73 HOH HOH A . H 5 HOH 74 874 74 HOH HOH A . H 5 HOH 75 875 75 HOH HOH A . H 5 HOH 76 876 76 HOH HOH A . H 5 HOH 77 877 77 HOH HOH A . H 5 HOH 78 878 78 HOH HOH A . H 5 HOH 79 879 79 HOH HOH A . H 5 HOH 80 880 80 HOH HOH A . H 5 HOH 81 881 81 HOH HOH A . H 5 HOH 82 882 82 HOH HOH A . H 5 HOH 83 883 83 HOH HOH A . H 5 HOH 84 884 84 HOH HOH A . H 5 HOH 85 885 85 HOH HOH A . H 5 HOH 86 886 86 HOH HOH A . H 5 HOH 87 887 87 HOH HOH A . H 5 HOH 88 888 88 HOH HOH A . H 5 HOH 89 889 89 HOH HOH A . H 5 HOH 90 890 90 HOH HOH A . H 5 HOH 91 891 91 HOH HOH A . H 5 HOH 92 892 92 HOH HOH A . H 5 HOH 93 893 93 HOH HOH A . H 5 HOH 94 894 94 HOH HOH A . H 5 HOH 95 895 95 HOH HOH A . H 5 HOH 96 896 96 HOH HOH A . H 5 HOH 97 897 97 HOH HOH A . H 5 HOH 98 898 98 HOH HOH A . H 5 HOH 99 899 99 HOH HOH A . H 5 HOH 100 900 100 HOH HOH A . H 5 HOH 101 901 101 HOH HOH A . H 5 HOH 102 902 102 HOH HOH A . H 5 HOH 103 903 103 HOH HOH A . H 5 HOH 104 904 104 HOH HOH A . H 5 HOH 105 905 105 HOH HOH A . H 5 HOH 106 906 106 HOH HOH A . H 5 HOH 107 907 107 HOH HOH A . H 5 HOH 108 908 108 HOH HOH A . H 5 HOH 109 909 109 HOH HOH A . H 5 HOH 110 910 110 HOH HOH A . H 5 HOH 111 911 111 HOH HOH A . H 5 HOH 112 912 112 HOH HOH A . H 5 HOH 113 913 113 HOH HOH A . H 5 HOH 114 914 114 HOH HOH A . H 5 HOH 115 915 115 HOH HOH A . H 5 HOH 116 916 116 HOH HOH A . H 5 HOH 117 917 117 HOH HOH A . H 5 HOH 118 918 118 HOH HOH A . H 5 HOH 119 919 119 HOH HOH A . H 5 HOH 120 920 120 HOH HOH A . H 5 HOH 121 921 121 HOH HOH A . H 5 HOH 122 922 122 HOH HOH A . H 5 HOH 123 923 123 HOH HOH A . H 5 HOH 124 924 124 HOH HOH A . H 5 HOH 125 925 125 HOH HOH A . H 5 HOH 126 926 126 HOH HOH A . H 5 HOH 127 927 127 HOH HOH A . H 5 HOH 128 928 128 HOH HOH A . H 5 HOH 129 929 129 HOH HOH A . H 5 HOH 130 930 130 HOH HOH A . H 5 HOH 131 931 131 HOH HOH A . H 5 HOH 132 932 132 HOH HOH A . H 5 HOH 133 933 133 HOH HOH A . H 5 HOH 134 934 134 HOH HOH A . H 5 HOH 135 935 135 HOH HOH A . H 5 HOH 136 936 136 HOH HOH A . H 5 HOH 137 937 137 HOH HOH A . H 5 HOH 138 938 138 HOH HOH A . H 5 HOH 139 939 139 HOH HOH A . H 5 HOH 140 940 140 HOH HOH A . H 5 HOH 141 941 141 HOH HOH A . H 5 HOH 142 942 142 HOH HOH A . H 5 HOH 143 943 143 HOH HOH A . H 5 HOH 144 944 144 HOH HOH A . H 5 HOH 145 945 145 HOH HOH A . H 5 HOH 146 946 146 HOH HOH A . H 5 HOH 147 947 147 HOH HOH A . H 5 HOH 148 948 148 HOH HOH A . H 5 HOH 149 949 149 HOH HOH A . H 5 HOH 150 950 150 HOH HOH A . H 5 HOH 151 951 151 HOH HOH A . H 5 HOH 152 952 152 HOH HOH A . H 5 HOH 153 953 153 HOH HOH A . H 5 HOH 154 954 154 HOH HOH A . H 5 HOH 155 955 155 HOH HOH A . H 5 HOH 156 956 156 HOH HOH A . H 5 HOH 157 957 157 HOH HOH A . H 5 HOH 158 958 158 HOH HOH A . H 5 HOH 159 959 159 HOH HOH A . H 5 HOH 160 960 160 HOH HOH A . H 5 HOH 161 961 161 HOH HOH A . H 5 HOH 162 962 162 HOH HOH A . H 5 HOH 163 963 163 HOH HOH A . H 5 HOH 164 964 164 HOH HOH A . H 5 HOH 165 965 165 HOH HOH A . H 5 HOH 166 966 166 HOH HOH A . H 5 HOH 167 967 167 HOH HOH A . H 5 HOH 168 968 168 HOH HOH A . H 5 HOH 169 969 169 HOH HOH A . H 5 HOH 170 970 170 HOH HOH A . H 5 HOH 171 971 171 HOH HOH A . H 5 HOH 172 972 172 HOH HOH A . H 5 HOH 173 973 173 HOH HOH A . H 5 HOH 174 974 174 HOH HOH A . H 5 HOH 175 975 175 HOH HOH A . H 5 HOH 176 976 176 HOH HOH A . H 5 HOH 177 977 177 HOH HOH A . H 5 HOH 178 978 178 HOH HOH A . H 5 HOH 179 979 179 HOH HOH A . H 5 HOH 180 980 180 HOH HOH A . H 5 HOH 181 981 181 HOH HOH A . H 5 HOH 182 982 182 HOH HOH A . H 5 HOH 183 983 183 HOH HOH A . H 5 HOH 184 984 184 HOH HOH A . H 5 HOH 185 985 185 HOH HOH A . H 5 HOH 186 986 186 HOH HOH A . H 5 HOH 187 987 187 HOH HOH A . H 5 HOH 188 988 188 HOH HOH A . H 5 HOH 189 989 189 HOH HOH A . H 5 HOH 190 990 190 HOH HOH A . H 5 HOH 191 991 191 HOH HOH A . H 5 HOH 192 992 192 HOH HOH A . H 5 HOH 193 993 193 HOH HOH A . H 5 HOH 194 994 194 HOH HOH A . H 5 HOH 195 995 195 HOH HOH A . H 5 HOH 196 996 196 HOH HOH A . H 5 HOH 197 997 197 HOH HOH A . H 5 HOH 198 998 198 HOH HOH A . H 5 HOH 199 999 199 HOH HOH A . H 5 HOH 200 1000 200 HOH HOH A . H 5 HOH 201 1001 201 HOH HOH A . H 5 HOH 202 1002 202 HOH HOH A . H 5 HOH 203 1003 203 HOH HOH A . H 5 HOH 204 1004 204 HOH HOH A . H 5 HOH 205 1005 205 HOH HOH A . H 5 HOH 206 1006 206 HOH HOH A . H 5 HOH 207 1007 207 HOH HOH A . H 5 HOH 208 1008 208 HOH HOH A . H 5 HOH 209 1009 209 HOH HOH A . H 5 HOH 210 1010 210 HOH HOH A . H 5 HOH 211 1011 211 HOH HOH A . H 5 HOH 212 1012 212 HOH HOH A . H 5 HOH 213 1013 213 HOH HOH A . H 5 HOH 214 1014 214 HOH HOH A . H 5 HOH 215 1015 215 HOH HOH A . H 5 HOH 216 1016 216 HOH HOH A . H 5 HOH 217 1017 217 HOH HOH A . H 5 HOH 218 1018 218 HOH HOH A . H 5 HOH 219 1019 219 HOH HOH A . H 5 HOH 220 1020 220 HOH HOH A . H 5 HOH 221 1021 221 HOH HOH A . H 5 HOH 222 1022 222 HOH HOH A . H 5 HOH 223 1023 223 HOH HOH A . H 5 HOH 224 1024 224 HOH HOH A . H 5 HOH 225 1025 225 HOH HOH A . H 5 HOH 226 1026 226 HOH HOH A . H 5 HOH 227 1027 227 HOH HOH A . H 5 HOH 228 1028 228 HOH HOH A . H 5 HOH 229 1029 229 HOH HOH A . H 5 HOH 230 1030 230 HOH HOH A . H 5 HOH 231 1031 231 HOH HOH A . H 5 HOH 232 1032 232 HOH HOH A . H 5 HOH 233 1033 233 HOH HOH A . H 5 HOH 234 1034 234 HOH HOH A . H 5 HOH 235 1035 235 HOH HOH A . H 5 HOH 236 1036 236 HOH HOH A . H 5 HOH 237 1037 237 HOH HOH A . H 5 HOH 238 1038 238 HOH HOH A . H 5 HOH 239 1039 239 HOH HOH A . H 5 HOH 240 1040 240 HOH HOH A . H 5 HOH 241 1041 241 HOH HOH A . H 5 HOH 242 1042 242 HOH HOH A . H 5 HOH 243 1043 243 HOH HOH A . H 5 HOH 244 1044 244 HOH HOH A . H 5 HOH 245 1045 245 HOH HOH A . H 5 HOH 246 1046 246 HOH HOH A . H 5 HOH 247 1047 247 HOH HOH A . H 5 HOH 248 1048 248 HOH HOH A . H 5 HOH 249 1049 249 HOH HOH A . H 5 HOH 250 1050 250 HOH HOH A . H 5 HOH 251 1051 251 HOH HOH A . H 5 HOH 252 1052 252 HOH HOH A . H 5 HOH 253 1053 253 HOH HOH A . H 5 HOH 254 1054 254 HOH HOH A . H 5 HOH 255 1055 255 HOH HOH A . H 5 HOH 256 1056 256 HOH HOH A . H 5 HOH 257 1057 257 HOH HOH A . H 5 HOH 258 1058 258 HOH HOH A . H 5 HOH 259 1059 259 HOH HOH A . H 5 HOH 260 1060 260 HOH HOH A . H 5 HOH 261 1061 261 HOH HOH A . H 5 HOH 262 1062 262 HOH HOH A . H 5 HOH 263 1063 263 HOH HOH A . H 5 HOH 264 1064 264 HOH HOH A . H 5 HOH 265 1065 265 HOH HOH A . H 5 HOH 266 1066 266 HOH HOH A . H 5 HOH 267 1067 267 HOH HOH A . H 5 HOH 268 1068 268 HOH HOH A . H 5 HOH 269 1069 269 HOH HOH A . H 5 HOH 270 1070 270 HOH HOH A . H 5 HOH 271 1071 271 HOH HOH A . H 5 HOH 272 1072 272 HOH HOH A . H 5 HOH 273 1073 273 HOH HOH A . H 5 HOH 274 1074 274 HOH HOH A . H 5 HOH 275 1075 275 HOH HOH A . H 5 HOH 276 1076 276 HOH HOH A . H 5 HOH 277 1077 277 HOH HOH A . H 5 HOH 278 1078 278 HOH HOH A . H 5 HOH 279 1079 279 HOH HOH A . H 5 HOH 280 1080 280 HOH HOH A . H 5 HOH 281 1081 281 HOH HOH A . H 5 HOH 282 1082 282 HOH HOH A . H 5 HOH 283 1083 283 HOH HOH A . H 5 HOH 284 1084 284 HOH HOH A . H 5 HOH 285 1085 285 HOH HOH A . H 5 HOH 286 1086 286 HOH HOH A . H 5 HOH 287 1087 287 HOH HOH A . H 5 HOH 288 1088 288 HOH HOH A . H 5 HOH 289 1089 289 HOH HOH A . H 5 HOH 290 1090 290 HOH HOH A . H 5 HOH 291 1091 291 HOH HOH A . H 5 HOH 292 1092 292 HOH HOH A . H 5 HOH 293 1093 293 HOH HOH A . H 5 HOH 294 1094 294 HOH HOH A . H 5 HOH 295 1095 295 HOH HOH A . H 5 HOH 296 1096 296 HOH HOH A . H 5 HOH 297 1097 297 HOH HOH A . H 5 HOH 298 1098 298 HOH HOH A . H 5 HOH 299 1099 299 HOH HOH A . H 5 HOH 300 1100 300 HOH HOH A . H 5 HOH 301 1101 301 HOH HOH A . H 5 HOH 302 1102 302 HOH HOH A . H 5 HOH 303 1103 303 HOH HOH A . H 5 HOH 304 1104 304 HOH HOH A . H 5 HOH 305 1105 305 HOH HOH A . H 5 HOH 306 1106 306 HOH HOH A . H 5 HOH 307 1107 307 HOH HOH A . H 5 HOH 308 1108 308 HOH HOH A . H 5 HOH 309 1109 309 HOH HOH A . H 5 HOH 310 1110 310 HOH HOH A . H 5 HOH 311 1111 311 HOH HOH A . H 5 HOH 312 1112 312 HOH HOH A . H 5 HOH 313 1113 313 HOH HOH A . H 5 HOH 314 1114 314 HOH HOH A . H 5 HOH 315 1115 315 HOH HOH A . H 5 HOH 316 1116 316 HOH HOH A . H 5 HOH 317 1117 317 HOH HOH A . H 5 HOH 318 1118 318 HOH HOH A . H 5 HOH 319 1119 319 HOH HOH A . H 5 HOH 320 1120 320 HOH HOH A . H 5 HOH 321 1121 321 HOH HOH A . H 5 HOH 322 1122 322 HOH HOH A . H 5 HOH 323 1123 323 HOH HOH A . H 5 HOH 324 1124 324 HOH HOH A . H 5 HOH 325 1125 325 HOH HOH A . H 5 HOH 326 1126 326 HOH HOH A . H 5 HOH 327 1127 327 HOH HOH A . H 5 HOH 328 1128 328 HOH HOH A . H 5 HOH 329 1129 329 HOH HOH A . H 5 HOH 330 1130 330 HOH HOH A . H 5 HOH 331 1131 331 HOH HOH A . H 5 HOH 332 1132 332 HOH HOH A . H 5 HOH 333 1133 333 HOH HOH A . H 5 HOH 334 1134 334 HOH HOH A . H 5 HOH 335 1135 335 HOH HOH A . H 5 HOH 336 1136 336 HOH HOH A . H 5 HOH 337 1137 337 HOH HOH A . H 5 HOH 338 1138 338 HOH HOH A . H 5 HOH 339 1139 339 HOH HOH A . H 5 HOH 340 1140 340 HOH HOH A . H 5 HOH 341 1141 341 HOH HOH A . H 5 HOH 342 1142 342 HOH HOH A . H 5 HOH 343 1143 343 HOH HOH A . H 5 HOH 344 1144 344 HOH HOH A . H 5 HOH 345 1145 345 HOH HOH A . H 5 HOH 346 1146 346 HOH HOH A . H 5 HOH 347 1147 347 HOH HOH A . H 5 HOH 348 1148 348 HOH HOH A . H 5 HOH 349 1149 349 HOH HOH A . H 5 HOH 350 1150 350 HOH HOH A . H 5 HOH 351 1151 351 HOH HOH A . H 5 HOH 352 1152 352 HOH HOH A . H 5 HOH 353 1153 353 HOH HOH A . H 5 HOH 354 1154 354 HOH HOH A . H 5 HOH 355 1155 355 HOH HOH A . H 5 HOH 356 1156 356 HOH HOH A . H 5 HOH 357 1157 357 HOH HOH A . H 5 HOH 358 1158 358 HOH HOH A . H 5 HOH 359 1159 359 HOH HOH A . H 5 HOH 360 1160 360 HOH HOH A . H 5 HOH 361 1161 361 HOH HOH A . H 5 HOH 362 1162 362 HOH HOH A . H 5 HOH 363 1163 363 HOH HOH A . H 5 HOH 364 1164 364 HOH HOH A . H 5 HOH 365 1165 365 HOH HOH A . H 5 HOH 366 1166 366 HOH HOH A . H 5 HOH 367 1167 367 HOH HOH A . H 5 HOH 368 1168 368 HOH HOH A . H 5 HOH 369 1169 369 HOH HOH A . H 5 HOH 370 1170 370 HOH HOH A . H 5 HOH 371 1171 371 HOH HOH A . H 5 HOH 372 1172 372 HOH HOH A . H 5 HOH 373 1173 373 HOH HOH A . H 5 HOH 374 1174 374 HOH HOH A . H 5 HOH 375 1175 375 HOH HOH A . H 5 HOH 376 1176 376 HOH HOH A . H 5 HOH 377 1177 377 HOH HOH A . H 5 HOH 378 1178 378 HOH HOH A . H 5 HOH 379 1179 379 HOH HOH A . H 5 HOH 380 1180 380 HOH HOH A . H 5 HOH 381 1181 381 HOH HOH A . H 5 HOH 382 1182 382 HOH HOH A . H 5 HOH 383 1183 383 HOH HOH A . H 5 HOH 384 1184 384 HOH HOH A . H 5 HOH 385 1185 385 HOH HOH A . H 5 HOH 386 1186 386 HOH HOH A . H 5 HOH 387 1187 387 HOH HOH A . H 5 HOH 388 1188 388 HOH HOH A . H 5 HOH 389 1189 389 HOH HOH A . H 5 HOH 390 1190 390 HOH HOH A . H 5 HOH 391 1191 391 HOH HOH A . H 5 HOH 392 1192 392 HOH HOH A . H 5 HOH 393 1193 393 HOH HOH A . H 5 HOH 394 1194 394 HOH HOH A . H 5 HOH 395 1195 395 HOH HOH A . H 5 HOH 396 1196 396 HOH HOH A . H 5 HOH 397 1197 397 HOH HOH A . H 5 HOH 398 1198 398 HOH HOH A . H 5 HOH 399 1199 399 HOH HOH A . H 5 HOH 400 1200 400 HOH HOH A . H 5 HOH 401 1201 401 HOH HOH A . H 5 HOH 402 1202 402 HOH HOH A . H 5 HOH 403 1203 403 HOH HOH A . H 5 HOH 404 1204 404 HOH HOH A . H 5 HOH 405 1205 405 HOH HOH A . H 5 HOH 406 1206 406 HOH HOH A . H 5 HOH 407 1207 407 HOH HOH A . H 5 HOH 408 1208 408 HOH HOH A . H 5 HOH 409 1209 409 HOH HOH A . H 5 HOH 410 1210 410 HOH HOH A . H 5 HOH 411 1211 411 HOH HOH A . H 5 HOH 412 1212 412 HOH HOH A . H 5 HOH 413 1213 413 HOH HOH A . H 5 HOH 414 1214 414 HOH HOH A . H 5 HOH 415 1215 415 HOH HOH A . H 5 HOH 416 1216 416 HOH HOH A . H 5 HOH 417 1217 417 HOH HOH A . H 5 HOH 418 1218 418 HOH HOH A . H 5 HOH 419 1219 419 HOH HOH A . H 5 HOH 420 1220 420 HOH HOH A . H 5 HOH 421 1221 421 HOH HOH A . H 5 HOH 422 1222 422 HOH HOH A . H 5 HOH 423 1223 423 HOH HOH A . H 5 HOH 424 1224 424 HOH HOH A . H 5 HOH 425 1225 425 HOH HOH A . H 5 HOH 426 1226 426 HOH HOH A . H 5 HOH 427 1227 427 HOH HOH A . H 5 HOH 428 1228 428 HOH HOH A . H 5 HOH 429 1229 429 HOH HOH A . H 5 HOH 430 1230 430 HOH HOH A . H 5 HOH 431 1231 431 HOH HOH A . H 5 HOH 432 1232 432 HOH HOH A . H 5 HOH 433 1233 433 HOH HOH A . H 5 HOH 434 1234 434 HOH HOH A . H 5 HOH 435 1235 435 HOH HOH A . H 5 HOH 436 1236 436 HOH HOH A . H 5 HOH 437 1237 437 HOH HOH A . H 5 HOH 438 1238 438 HOH HOH A . H 5 HOH 439 1239 439 HOH HOH A . H 5 HOH 440 1240 440 HOH HOH A . H 5 HOH 441 1241 441 HOH HOH A . H 5 HOH 442 1242 442 HOH HOH A . H 5 HOH 443 1243 443 HOH HOH A . H 5 HOH 444 1244 444 HOH HOH A . H 5 HOH 445 1245 445 HOH HOH A . H 5 HOH 446 1246 446 HOH HOH A . H 5 HOH 447 1247 447 HOH HOH A . H 5 HOH 448 1248 448 HOH HOH A . H 5 HOH 449 1249 449 HOH HOH A . H 5 HOH 450 1250 450 HOH HOH A . H 5 HOH 451 1251 451 HOH HOH A . H 5 HOH 452 1252 452 HOH HOH A . H 5 HOH 453 1253 453 HOH HOH A . H 5 HOH 454 1254 454 HOH HOH A . H 5 HOH 455 1255 455 HOH HOH A . H 5 HOH 456 1256 456 HOH HOH A . H 5 HOH 457 1257 457 HOH HOH A . H 5 HOH 458 1258 458 HOH HOH A . H 5 HOH 459 1259 459 HOH HOH A . H 5 HOH 460 1260 460 HOH HOH A . H 5 HOH 461 1261 461 HOH HOH A . H 5 HOH 462 1262 462 HOH HOH A . H 5 HOH 463 1263 463 HOH HOH A . H 5 HOH 464 1264 464 HOH HOH A . H 5 HOH 465 1265 465 HOH HOH A . H 5 HOH 466 1266 466 HOH HOH A . H 5 HOH 467 1267 467 HOH HOH A . H 5 HOH 468 1268 468 HOH HOH A . H 5 HOH 469 1269 469 HOH HOH A . H 5 HOH 470 1270 470 HOH HOH A . H 5 HOH 471 1271 471 HOH HOH A . H 5 HOH 472 1272 472 HOH HOH A . H 5 HOH 473 1273 473 HOH HOH A . H 5 HOH 474 1274 474 HOH HOH A . H 5 HOH 475 1275 475 HOH HOH A . H 5 HOH 476 1276 476 HOH HOH A . H 5 HOH 477 1277 477 HOH HOH A . H 5 HOH 478 1278 478 HOH HOH A . H 5 HOH 479 1279 479 HOH HOH A . H 5 HOH 480 1280 480 HOH HOH A . H 5 HOH 481 1281 481 HOH HOH A . H 5 HOH 482 1282 482 HOH HOH A . H 5 HOH 483 1283 483 HOH HOH A . H 5 HOH 484 1284 484 HOH HOH A . H 5 HOH 485 1285 485 HOH HOH A . H 5 HOH 486 1286 486 HOH HOH A . H 5 HOH 487 1287 487 HOH HOH A . H 5 HOH 488 1288 488 HOH HOH A . H 5 HOH 489 1289 489 HOH HOH A . H 5 HOH 490 1290 490 HOH HOH A . H 5 HOH 491 1291 491 HOH HOH A . H 5 HOH 492 1292 492 HOH HOH A . H 5 HOH 493 1293 493 HOH HOH A . H 5 HOH 494 1294 494 HOH HOH A . H 5 HOH 495 1295 495 HOH HOH A . H 5 HOH 496 1296 496 HOH HOH A . H 5 HOH 497 1297 497 HOH HOH A . H 5 HOH 498 1298 498 HOH HOH A . H 5 HOH 499 1299 499 HOH HOH A . H 5 HOH 500 1300 500 HOH HOH A . H 5 HOH 501 1301 501 HOH HOH A . H 5 HOH 502 1302 502 HOH HOH A . H 5 HOH 503 1303 503 HOH HOH A . H 5 HOH 504 1304 504 HOH HOH A . H 5 HOH 505 1305 505 HOH HOH A . H 5 HOH 506 1306 506 HOH HOH A . H 5 HOH 507 1307 507 HOH HOH A . H 5 HOH 508 1308 508 HOH HOH A . H 5 HOH 509 1309 509 HOH HOH A . H 5 HOH 510 1310 510 HOH HOH A . H 5 HOH 511 1311 511 HOH HOH A . H 5 HOH 512 1312 512 HOH HOH A . H 5 HOH 513 1313 513 HOH HOH A . H 5 HOH 514 1314 514 HOH HOH A . H 5 HOH 515 1315 515 HOH HOH A . H 5 HOH 516 1316 516 HOH HOH A . H 5 HOH 517 1317 517 HOH HOH A . H 5 HOH 518 1318 518 HOH HOH A . H 5 HOH 519 1319 519 HOH HOH A . H 5 HOH 520 1320 520 HOH HOH A . H 5 HOH 521 1321 521 HOH HOH A . H 5 HOH 522 1322 522 HOH HOH A . H 5 HOH 523 1323 523 HOH HOH A . H 5 HOH 524 1324 524 HOH HOH A . H 5 HOH 525 1325 525 HOH HOH A . H 5 HOH 526 1326 526 HOH HOH A . H 5 HOH 527 1327 527 HOH HOH A . H 5 HOH 528 1328 528 HOH HOH A . H 5 HOH 529 1329 529 HOH HOH A . H 5 HOH 530 1330 530 HOH HOH A . H 5 HOH 531 1331 531 HOH HOH A . H 5 HOH 532 1332 532 HOH HOH A . H 5 HOH 533 1333 533 HOH HOH A . H 5 HOH 534 1334 534 HOH HOH A . H 5 HOH 535 1335 535 HOH HOH A . H 5 HOH 536 1336 536 HOH HOH A . H 5 HOH 537 1337 537 HOH HOH A . H 5 HOH 538 1338 538 HOH HOH A . H 5 HOH 539 1339 539 HOH HOH A . H 5 HOH 540 1340 540 HOH HOH A . H 5 HOH 541 1341 541 HOH HOH A . H 5 HOH 542 1342 542 HOH HOH A . H 5 HOH 543 1343 543 HOH HOH A . H 5 HOH 544 1344 544 HOH HOH A . H 5 HOH 545 1345 545 HOH HOH A . H 5 HOH 546 1346 546 HOH HOH A . H 5 HOH 547 1347 547 HOH HOH A . H 5 HOH 548 1348 548 HOH HOH A . H 5 HOH 549 1349 549 HOH HOH A . H 5 HOH 550 1350 550 HOH HOH A . H 5 HOH 551 1351 551 HOH HOH A . H 5 HOH 552 1352 552 HOH HOH A . H 5 HOH 553 1353 553 HOH HOH A . H 5 HOH 554 1354 554 HOH HOH A . H 5 HOH 555 1355 555 HOH HOH A . H 5 HOH 556 1356 556 HOH HOH A . H 5 HOH 557 1357 557 HOH HOH A . H 5 HOH 558 1358 558 HOH HOH A . H 5 HOH 559 1359 559 HOH HOH A . H 5 HOH 560 1360 560 HOH HOH A . H 5 HOH 561 1361 561 HOH HOH A . H 5 HOH 562 1362 562 HOH HOH A . H 5 HOH 563 1363 563 HOH HOH A . H 5 HOH 564 1364 564 HOH HOH A . H 5 HOH 565 1365 565 HOH HOH A . H 5 HOH 566 1366 566 HOH HOH A . H 5 HOH 567 1367 567 HOH HOH A . H 5 HOH 568 1368 568 HOH HOH A . H 5 HOH 569 1369 569 HOH HOH A . H 5 HOH 570 1370 570 HOH HOH A . H 5 HOH 571 1371 571 HOH HOH A . H 5 HOH 572 1372 572 HOH HOH A . H 5 HOH 573 1373 573 HOH HOH A . H 5 HOH 574 1374 574 HOH HOH A . H 5 HOH 575 1375 575 HOH HOH A . H 5 HOH 576 1376 576 HOH HOH A . H 5 HOH 577 1377 577 HOH HOH A . H 5 HOH 578 1378 578 HOH HOH A . H 5 HOH 579 1379 579 HOH HOH A . H 5 HOH 580 1380 580 HOH HOH A . H 5 HOH 581 1381 581 HOH HOH A . H 5 HOH 582 1382 582 HOH HOH A . H 5 HOH 583 1383 583 HOH HOH A . H 5 HOH 584 1384 584 HOH HOH A . H 5 HOH 585 1385 585 HOH HOH A . H 5 HOH 586 1386 586 HOH HOH A . H 5 HOH 587 1387 587 HOH HOH A . H 5 HOH 588 1388 588 HOH HOH A . H 5 HOH 589 1389 589 HOH HOH A . H 5 HOH 590 1390 590 HOH HOH A . H 5 HOH 591 1391 591 HOH HOH A . H 5 HOH 592 1392 592 HOH HOH A . H 5 HOH 593 1393 593 HOH HOH A . H 5 HOH 594 1394 594 HOH HOH A . H 5 HOH 595 1395 595 HOH HOH A . H 5 HOH 596 1396 596 HOH HOH A . H 5 HOH 597 1397 597 HOH HOH A . H 5 HOH 598 1398 598 HOH HOH A . H 5 HOH 599 1399 599 HOH HOH A . H 5 HOH 600 1400 600 HOH HOH A . H 5 HOH 601 1401 601 HOH HOH A . H 5 HOH 602 1402 602 HOH HOH A . H 5 HOH 603 1403 603 HOH HOH A . H 5 HOH 604 1404 604 HOH HOH A . H 5 HOH 605 1405 605 HOH HOH A . H 5 HOH 606 1406 606 HOH HOH A . H 5 HOH 607 1407 607 HOH HOH A . H 5 HOH 608 1408 608 HOH HOH A . H 5 HOH 609 1409 609 HOH HOH A . H 5 HOH 610 1410 610 HOH HOH A . H 5 HOH 611 1411 611 HOH HOH A . H 5 HOH 612 1412 612 HOH HOH A . H 5 HOH 613 1413 613 HOH HOH A . H 5 HOH 614 1414 614 HOH HOH A . H 5 HOH 615 1415 615 HOH HOH A . H 5 HOH 616 1416 616 HOH HOH A . H 5 HOH 617 1417 617 HOH HOH A . H 5 HOH 618 1418 618 HOH HOH A . H 5 HOH 619 1419 619 HOH HOH A . H 5 HOH 620 1420 620 HOH HOH A . H 5 HOH 621 1421 621 HOH HOH A . H 5 HOH 622 1422 622 HOH HOH A . H 5 HOH 623 1423 623 HOH HOH A . H 5 HOH 624 1424 624 HOH HOH A . H 5 HOH 625 1425 625 HOH HOH A . H 5 HOH 626 1426 626 HOH HOH A . H 5 HOH 627 1427 627 HOH HOH A . H 5 HOH 628 1428 628 HOH HOH A . H 5 HOH 629 1429 629 HOH HOH A . H 5 HOH 630 1430 630 HOH HOH A . H 5 HOH 631 1431 631 HOH HOH A . H 5 HOH 632 1432 632 HOH HOH A . H 5 HOH 633 1433 633 HOH HOH A . H 5 HOH 634 1434 634 HOH HOH A . H 5 HOH 635 1435 635 HOH HOH A . H 5 HOH 636 1436 636 HOH HOH A . H 5 HOH 637 1437 637 HOH HOH A . H 5 HOH 638 1438 638 HOH HOH A . H 5 HOH 639 1439 639 HOH HOH A . H 5 HOH 640 1440 640 HOH HOH A . H 5 HOH 641 1441 641 HOH HOH A . H 5 HOH 642 1442 642 HOH HOH A . H 5 HOH 643 1443 643 HOH HOH A . H 5 HOH 644 1444 644 HOH HOH A . H 5 HOH 645 1445 645 HOH HOH A . H 5 HOH 646 1446 646 HOH HOH A . H 5 HOH 647 1447 647 HOH HOH A . H 5 HOH 648 1448 648 HOH HOH A . H 5 HOH 649 1449 649 HOH HOH A . H 5 HOH 650 1450 650 HOH HOH A . H 5 HOH 651 1451 651 HOH HOH A . H 5 HOH 652 1452 652 HOH HOH A . H 5 HOH 653 1453 653 HOH HOH A . H 5 HOH 654 1454 654 HOH HOH A . H 5 HOH 655 1455 655 HOH HOH A . H 5 HOH 656 1456 656 HOH HOH A . H 5 HOH 657 1457 657 HOH HOH A . H 5 HOH 658 1458 658 HOH HOH A . H 5 HOH 659 1459 659 HOH HOH A . H 5 HOH 660 1460 660 HOH HOH A . H 5 HOH 661 1461 661 HOH HOH A . H 5 HOH 662 1462 662 HOH HOH A . H 5 HOH 663 1463 663 HOH HOH A . H 5 HOH 664 1464 664 HOH HOH A . H 5 HOH 665 1465 665 HOH HOH A . H 5 HOH 666 1466 666 HOH HOH A . H 5 HOH 667 1467 667 HOH HOH A . H 5 HOH 668 1468 668 HOH HOH A . H 5 HOH 669 1469 669 HOH HOH A . H 5 HOH 670 1470 670 HOH HOH A . H 5 HOH 671 1471 671 HOH HOH A . H 5 HOH 672 1472 672 HOH HOH A . H 5 HOH 673 1473 673 HOH HOH A . H 5 HOH 674 1474 674 HOH HOH A . H 5 HOH 675 1475 675 HOH HOH A . H 5 HOH 676 1476 676 HOH HOH A . H 5 HOH 677 1477 677 HOH HOH A . H 5 HOH 678 1478 678 HOH HOH A . H 5 HOH 679 1479 679 HOH HOH A . H 5 HOH 680 1480 680 HOH HOH A . H 5 HOH 681 1481 681 HOH HOH A . H 5 HOH 682 1482 682 HOH HOH A . H 5 HOH 683 1483 683 HOH HOH A . H 5 HOH 684 1484 684 HOH HOH A . H 5 HOH 685 1485 685 HOH HOH A . H 5 HOH 686 1486 686 HOH HOH A . H 5 HOH 687 1487 687 HOH HOH A . H 5 HOH 688 1488 688 HOH HOH A . H 5 HOH 689 1489 689 HOH HOH A . H 5 HOH 690 1490 690 HOH HOH A . H 5 HOH 691 1491 691 HOH HOH A . H 5 HOH 692 1492 692 HOH HOH A . H 5 HOH 693 1493 693 HOH HOH A . H 5 HOH 694 1494 694 HOH HOH A . H 5 HOH 695 1495 695 HOH HOH A . H 5 HOH 696 1496 696 HOH HOH A . H 5 HOH 697 1497 697 HOH HOH A . H 5 HOH 698 1498 698 HOH HOH A . H 5 HOH 699 1499 699 HOH HOH A . H 5 HOH 700 1500 700 HOH HOH A . H 5 HOH 701 1501 701 HOH HOH A . H 5 HOH 702 1502 702 HOH HOH A . H 5 HOH 703 1503 703 HOH HOH A . H 5 HOH 704 1504 704 HOH HOH A . H 5 HOH 705 1505 705 HOH HOH A . H 5 HOH 706 1506 706 HOH HOH A . H 5 HOH 707 1507 707 HOH HOH A . H 5 HOH 708 1508 708 HOH HOH A . H 5 HOH 709 1509 709 HOH HOH A . H 5 HOH 710 1510 710 HOH HOH A . H 5 HOH 711 1511 711 HOH HOH A . H 5 HOH 712 1512 712 HOH HOH A . H 5 HOH 713 1513 713 HOH HOH A . H 5 HOH 714 1514 714 HOH HOH A . H 5 HOH 715 1515 715 HOH HOH A . H 5 HOH 716 1516 716 HOH HOH A . H 5 HOH 717 1517 717 HOH HOH A . H 5 HOH 718 1518 718 HOH HOH A . H 5 HOH 719 1519 719 HOH HOH A . H 5 HOH 720 1520 720 HOH HOH A . H 5 HOH 721 1521 721 HOH HOH A . H 5 HOH 722 1522 722 HOH HOH A . H 5 HOH 723 1523 723 HOH HOH A . H 5 HOH 724 1524 724 HOH HOH A . H 5 HOH 725 1525 725 HOH HOH A . H 5 HOH 726 1526 726 HOH HOH A . H 5 HOH 727 1527 727 HOH HOH A . H 5 HOH 728 1528 728 HOH HOH A . H 5 HOH 729 1529 729 HOH HOH A . H 5 HOH 730 1530 730 HOH HOH A . H 5 HOH 731 1531 731 HOH HOH A . H 5 HOH 732 1532 732 HOH HOH A . H 5 HOH 733 1533 733 HOH HOH A . H 5 HOH 734 1534 734 HOH HOH A . H 5 HOH 735 1535 735 HOH HOH A . H 5 HOH 736 1536 736 HOH HOH A . H 5 HOH 737 1537 737 HOH HOH A . H 5 HOH 738 1538 738 HOH HOH A . H 5 HOH 739 1539 739 HOH HOH A . H 5 HOH 740 1540 740 HOH HOH A . H 5 HOH 741 1541 741 HOH HOH A . H 5 HOH 742 1542 742 HOH HOH A . H 5 HOH 743 1543 743 HOH HOH A . H 5 HOH 744 1544 744 HOH HOH A . H 5 HOH 745 1545 745 HOH HOH A . H 5 HOH 746 1546 746 HOH HOH A . H 5 HOH 747 1547 747 HOH HOH A . H 5 HOH 748 1548 748 HOH HOH A . H 5 HOH 749 1549 749 HOH HOH A . H 5 HOH 750 1550 750 HOH HOH A . H 5 HOH 751 1551 751 HOH HOH A . H 5 HOH 752 1552 752 HOH HOH A . H 5 HOH 753 1553 753 HOH HOH A . H 5 HOH 754 1554 754 HOH HOH A . H 5 HOH 755 1555 755 HOH HOH A . H 5 HOH 756 1556 756 HOH HOH A . H 5 HOH 757 1557 757 HOH HOH A . H 5 HOH 758 1558 758 HOH HOH A . H 5 HOH 759 1559 759 HOH HOH A . H 5 HOH 760 1560 760 HOH HOH A . H 5 HOH 761 1561 761 HOH HOH A . H 5 HOH 762 1562 762 HOH HOH A . H 5 HOH 763 1563 763 HOH HOH A . H 5 HOH 764 1564 764 HOH HOH A . H 5 HOH 765 1565 765 HOH HOH A . H 5 HOH 766 1566 766 HOH HOH A . H 5 HOH 767 1567 767 HOH HOH A . H 5 HOH 768 1568 768 HOH HOH A . H 5 HOH 769 1569 769 HOH HOH A . H 5 HOH 770 1570 770 HOH HOH A . H 5 HOH 771 1571 771 HOH HOH A . H 5 HOH 772 1572 772 HOH HOH A . H 5 HOH 773 1573 773 HOH HOH A . H 5 HOH 774 1574 774 HOH HOH A . H 5 HOH 775 1575 775 HOH HOH A . H 5 HOH 776 1576 776 HOH HOH A . H 5 HOH 777 1577 777 HOH HOH A . H 5 HOH 778 1578 778 HOH HOH A . H 5 HOH 779 1579 779 HOH HOH A . H 5 HOH 780 1580 780 HOH HOH A . H 5 HOH 781 1581 781 HOH HOH A . H 5 HOH 782 1582 782 HOH HOH A . H 5 HOH 783 1583 783 HOH HOH A . H 5 HOH 784 1584 784 HOH HOH A . H 5 HOH 785 1585 785 HOH HOH A . H 5 HOH 786 1586 786 HOH HOH A . H 5 HOH 787 1587 787 HOH HOH A . H 5 HOH 788 1588 788 HOH HOH A . H 5 HOH 789 1589 789 HOH HOH A . H 5 HOH 790 1590 790 HOH HOH A . H 5 HOH 791 1591 791 HOH HOH A . H 5 HOH 792 1592 792 HOH HOH A . H 5 HOH 793 1593 793 HOH HOH A . H 5 HOH 794 1594 794 HOH HOH A . H 5 HOH 795 1595 795 HOH HOH A . H 5 HOH 796 1596 796 HOH HOH A . H 5 HOH 797 1597 797 HOH HOH A . H 5 HOH 798 1598 798 HOH HOH A . H 5 HOH 799 1599 799 HOH HOH A . H 5 HOH 800 1600 800 HOH HOH A . H 5 HOH 801 1601 801 HOH HOH A . H 5 HOH 802 1602 802 HOH HOH A . H 5 HOH 803 1603 803 HOH HOH A . H 5 HOH 804 1604 804 HOH HOH A . H 5 HOH 805 1605 805 HOH HOH A . H 5 HOH 806 1606 806 HOH HOH A . H 5 HOH 807 1607 807 HOH HOH A . H 5 HOH 808 1608 808 HOH HOH A . H 5 HOH 809 1609 809 HOH HOH A . H 5 HOH 810 1610 810 HOH HOH A . H 5 HOH 811 1611 811 HOH HOH A . H 5 HOH 812 1612 812 HOH HOH A . H 5 HOH 813 1613 813 HOH HOH A . H 5 HOH 814 1614 814 HOH HOH A . H 5 HOH 815 1615 815 HOH HOH A . H 5 HOH 816 1616 816 HOH HOH A . H 5 HOH 817 1617 817 HOH HOH A . H 5 HOH 818 1618 818 HOH HOH A . H 5 HOH 819 1619 819 HOH HOH A . H 5 HOH 820 1620 820 HOH HOH A . H 5 HOH 821 1621 821 HOH HOH A . H 5 HOH 822 1622 822 HOH HOH A . H 5 HOH 823 1623 823 HOH HOH A . H 5 HOH 824 1624 824 HOH HOH A . H 5 HOH 825 1625 825 HOH HOH A . H 5 HOH 826 1626 826 HOH HOH A . H 5 HOH 827 1627 827 HOH HOH A . H 5 HOH 828 1628 828 HOH HOH A . H 5 HOH 829 1629 829 HOH HOH A . H 5 HOH 830 1630 830 HOH HOH A . H 5 HOH 831 1631 831 HOH HOH A . H 5 HOH 832 1632 832 HOH HOH A . H 5 HOH 833 1633 833 HOH HOH A . H 5 HOH 834 1634 834 HOH HOH A . H 5 HOH 835 1635 835 HOH HOH A . H 5 HOH 836 1636 836 HOH HOH A . H 5 HOH 837 1637 837 HOH HOH A . H 5 HOH 838 1638 838 HOH HOH A . H 5 HOH 839 1639 839 HOH HOH A . H 5 HOH 840 1640 840 HOH HOH A . H 5 HOH 841 1641 841 HOH HOH A . H 5 HOH 842 1642 842 HOH HOH A . H 5 HOH 843 1643 843 HOH HOH A . H 5 HOH 844 1644 844 HOH HOH A . H 5 HOH 845 1645 845 HOH HOH A . H 5 HOH 846 1646 846 HOH HOH A . H 5 HOH 847 1647 847 HOH HOH A . H 5 HOH 848 1648 848 HOH HOH A . H 5 HOH 849 1649 849 HOH HOH A . H 5 HOH 850 1650 850 HOH HOH A . H 5 HOH 851 1651 851 HOH HOH A . H 5 HOH 852 1652 852 HOH HOH A . H 5 HOH 853 1653 853 HOH HOH A . H 5 HOH 854 1654 854 HOH HOH A . H 5 HOH 855 1655 855 HOH HOH A . H 5 HOH 856 1656 856 HOH HOH A . H 5 HOH 857 1657 857 HOH HOH A . H 5 HOH 858 1658 858 HOH HOH A . H 5 HOH 859 1659 859 HOH HOH A . H 5 HOH 860 1660 860 HOH HOH A . H 5 HOH 861 1661 861 HOH HOH A . H 5 HOH 862 1662 862 HOH HOH A . H 5 HOH 863 1663 863 HOH HOH A . H 5 HOH 864 1664 864 HOH HOH A . H 5 HOH 865 1665 865 HOH HOH A . H 5 HOH 866 1666 866 HOH HOH A . H 5 HOH 867 1667 867 HOH HOH A . H 5 HOH 868 1668 868 HOH HOH A . H 5 HOH 869 1669 869 HOH HOH A . H 5 HOH 870 1670 870 HOH HOH A . H 5 HOH 871 1671 871 HOH HOH A . H 5 HOH 872 1672 872 HOH HOH A . H 5 HOH 873 1673 873 HOH HOH A . H 5 HOH 874 1674 874 HOH HOH A . H 5 HOH 875 1675 875 HOH HOH A . H 5 HOH 876 1676 876 HOH HOH A . H 5 HOH 877 1677 877 HOH HOH A . H 5 HOH 878 1678 878 HOH HOH A . H 5 HOH 879 1679 879 HOH HOH A . H 5 HOH 880 1680 880 HOH HOH A . H 5 HOH 881 1681 881 HOH HOH A . H 5 HOH 882 1682 882 HOH HOH A . H 5 HOH 883 1683 883 HOH HOH A . H 5 HOH 884 1684 884 HOH HOH A . H 5 HOH 885 1685 885 HOH HOH A . H 5 HOH 886 1686 886 HOH HOH A . H 5 HOH 887 1687 887 HOH HOH A . H 5 HOH 888 1688 888 HOH HOH A . H 5 HOH 889 1689 889 HOH HOH A . H 5 HOH 890 1690 890 HOH HOH A . H 5 HOH 891 1691 891 HOH HOH A . H 5 HOH 892 1692 892 HOH HOH A . H 5 HOH 893 1693 893 HOH HOH A . H 5 HOH 894 1694 894 HOH HOH A . H 5 HOH 895 1695 895 HOH HOH A . H 5 HOH 896 1696 896 HOH HOH A . H 5 HOH 897 1697 897 HOH HOH A . H 5 HOH 898 1698 898 HOH HOH A . H 5 HOH 899 1699 899 HOH HOH A . H 5 HOH 900 1700 900 HOH HOH A . H 5 HOH 901 1701 901 HOH HOH A . H 5 HOH 902 1702 902 HOH HOH A . H 5 HOH 903 1703 903 HOH HOH A . H 5 HOH 904 1704 904 HOH HOH A . H 5 HOH 905 1705 905 HOH HOH A . H 5 HOH 906 1706 906 HOH HOH A . H 5 HOH 907 1707 907 HOH HOH A . H 5 HOH 908 1708 908 HOH HOH A . H 5 HOH 909 1709 909 HOH HOH A . H 5 HOH 910 1710 910 HOH HOH A . H 5 HOH 911 1711 911 HOH HOH A . H 5 HOH 912 1712 912 HOH HOH A . H 5 HOH 913 1713 913 HOH HOH A . H 5 HOH 914 1714 914 HOH HOH A . H 5 HOH 915 1715 915 HOH HOH A . H 5 HOH 916 1716 916 HOH HOH A . H 5 HOH 917 1717 917 HOH HOH A . H 5 HOH 918 1718 918 HOH HOH A . H 5 HOH 919 1719 919 HOH HOH A . H 5 HOH 920 1720 920 HOH HOH A . H 5 HOH 921 1721 921 HOH HOH A . H 5 HOH 922 1722 922 HOH HOH A . H 5 HOH 923 1723 923 HOH HOH A . H 5 HOH 924 1724 924 HOH HOH A . H 5 HOH 925 1725 925 HOH HOH A . H 5 HOH 926 1726 926 HOH HOH A . H 5 HOH 927 1727 927 HOH HOH A . H 5 HOH 928 1728 928 HOH HOH A . H 5 HOH 929 1729 929 HOH HOH A . H 5 HOH 930 1730 930 HOH HOH A . H 5 HOH 931 1731 931 HOH HOH A . H 5 HOH 932 1732 932 HOH HOH A . H 5 HOH 933 1733 933 HOH HOH A . H 5 HOH 934 1734 934 HOH HOH A . H 5 HOH 935 1735 935 HOH HOH A . H 5 HOH 936 1736 936 HOH HOH A . H 5 HOH 937 1737 937 HOH HOH A . H 5 HOH 938 1738 938 HOH HOH A . H 5 HOH 939 1739 939 HOH HOH A . H 5 HOH 940 1740 940 HOH HOH A . H 5 HOH 941 1741 941 HOH HOH A . H 5 HOH 942 1742 942 HOH HOH A . H 5 HOH 943 1743 943 HOH HOH A . H 5 HOH 944 1744 944 HOH HOH A . H 5 HOH 945 1745 945 HOH HOH A . H 5 HOH 946 1746 946 HOH HOH A . H 5 HOH 947 1747 947 HOH HOH A . H 5 HOH 948 1748 948 HOH HOH A . H 5 HOH 949 1749 949 HOH HOH A . H 5 HOH 950 1750 950 HOH HOH A . H 5 HOH 951 1751 951 HOH HOH A . H 5 HOH 952 1752 952 HOH HOH A . H 5 HOH 953 1753 953 HOH HOH A . H 5 HOH 954 1754 954 HOH HOH A . H 5 HOH 955 1755 955 HOH HOH A . H 5 HOH 956 1756 956 HOH HOH A . H 5 HOH 957 1757 957 HOH HOH A . H 5 HOH 958 1758 958 HOH HOH A . H 5 HOH 959 1759 959 HOH HOH A . H 5 HOH 960 1760 960 HOH HOH A . H 5 HOH 961 1761 961 HOH HOH A . H 5 HOH 962 1762 962 HOH HOH A . H 5 HOH 963 1763 963 HOH HOH A . H 5 HOH 964 1764 964 HOH HOH A . H 5 HOH 965 1765 965 HOH HOH A . H 5 HOH 966 1766 966 HOH HOH A . H 5 HOH 967 1767 967 HOH HOH A . H 5 HOH 968 1768 968 HOH HOH A . H 5 HOH 969 1769 969 HOH HOH A . H 5 HOH 970 1770 970 HOH HOH A . H 5 HOH 971 1771 971 HOH HOH A . H 5 HOH 972 1772 972 HOH HOH A . H 5 HOH 973 1773 973 HOH HOH A . H 5 HOH 974 1774 974 HOH HOH A . H 5 HOH 975 1775 975 HOH HOH A . H 5 HOH 976 1776 976 HOH HOH A . H 5 HOH 977 1777 977 HOH HOH A . H 5 HOH 978 1778 978 HOH HOH A . H 5 HOH 979 1779 979 HOH HOH A . H 5 HOH 980 1780 980 HOH HOH A . H 5 HOH 981 1781 981 HOH HOH A . H 5 HOH 982 1782 982 HOH HOH A . H 5 HOH 983 1783 983 HOH HOH A . H 5 HOH 984 1784 984 HOH HOH A . H 5 HOH 985 1785 985 HOH HOH A . H 5 HOH 986 1786 986 HOH HOH A . H 5 HOH 987 1787 987 HOH HOH A . H 5 HOH 988 1788 988 HOH HOH A . H 5 HOH 989 1789 989 HOH HOH A . H 5 HOH 990 1790 990 HOH HOH A . H 5 HOH 991 1791 991 HOH HOH A . H 5 HOH 992 1792 992 HOH HOH A . H 5 HOH 993 1793 993 HOH HOH A . H 5 HOH 994 1794 994 HOH HOH A . H 5 HOH 995 1795 995 HOH HOH A . H 5 HOH 996 1796 996 HOH HOH A . H 5 HOH 997 1797 997 HOH HOH A . H 5 HOH 998 1798 998 HOH HOH A . H 5 HOH 999 1799 999 HOH HOH A . H 5 HOH 1000 1800 1000 HOH HOH A . H 5 HOH 1001 1801 1001 HOH HOH A . H 5 HOH 1002 1802 1002 HOH HOH A . H 5 HOH 1003 1803 1003 HOH HOH A . H 5 HOH 1004 1804 1004 HOH HOH A . H 5 HOH 1005 1805 1005 HOH HOH A . H 5 HOH 1006 1806 1006 HOH HOH A . H 5 HOH 1007 1807 1007 HOH HOH A . H 5 HOH 1008 1808 1008 HOH HOH A . H 5 HOH 1009 1809 1009 HOH HOH A . H 5 HOH 1010 1810 1010 HOH HOH A . H 5 HOH 1011 1811 1011 HOH HOH A . H 5 HOH 1012 1812 1012 HOH HOH A . H 5 HOH 1013 1813 1013 HOH HOH A . H 5 HOH 1014 1814 1014 HOH HOH A . H 5 HOH 1015 1815 1015 HOH HOH A . H 5 HOH 1016 1816 1016 HOH HOH A . H 5 HOH 1017 1817 1017 HOH HOH A . H 5 HOH 1018 1818 1018 HOH HOH A . H 5 HOH 1019 1819 1019 HOH HOH A . H 5 HOH 1020 1820 1020 HOH HOH A . H 5 HOH 1021 1821 1021 HOH HOH A . H 5 HOH 1022 1822 1022 HOH HOH A . H 5 HOH 1023 1823 1023 HOH HOH A . H 5 HOH 1024 1824 1024 HOH HOH A . H 5 HOH 1025 1825 1025 HOH HOH A . #