data_3Q2W # _entry.id 3Q2W # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.281 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3Q2W RCSB RCSB063125 WWPDB D_1000063125 # _pdbx_database_related.db_name PDB _pdbx_database_related.db_id 3Q2V _pdbx_database_related.details . _pdbx_database_related.content_type unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 3Q2W _pdbx_database_status.recvd_initial_deposition_date 2010-12-20 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Jin, X.' 1 'Shapiro, L.' 2 # _citation.id primary _citation.title 'The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins.' _citation.journal_abbrev Structure _citation.journal_volume 19 _citation.page_first 244 _citation.page_last 256 _citation.year 2011 _citation.journal_id_ASTM STRUE6 _citation.country UK _citation.journal_id_ISSN 0969-2126 _citation.journal_id_CSD 2005 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 21300292 _citation.pdbx_database_id_DOI 10.1016/j.str.2010.11.016 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Harrison, O.J.' 1 primary 'Jin, X.' 2 primary 'Hong, S.' 3 primary 'Bahna, F.' 4 primary 'Ahlsen, G.' 5 primary 'Brasch, J.' 6 primary 'Wu, Y.' 7 primary 'Vendome, J.' 8 primary 'Felsovalyi, K.' 9 primary 'Hampton, C.M.' 10 primary 'Troyanovsky, R.B.' 11 primary 'Ben-Shaul, A.' 12 primary 'Frank, J.' 13 primary 'Troyanovsky, S.M.' 14 primary 'Shapiro, L.' 15 primary 'Honig, B.' 16 # _cell.entry_id 3Q2W _cell.length_a 91.372 _cell.length_b 111.648 _cell.length_c 262.107 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 3Q2W _symmetry.space_group_name_H-M 'C 2 2 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 20 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man Cadherin-2 61529.699 1 ? ? 'UNP residues 160-711' ? 2 non-polymer syn 'CALCIUM ION' 40.078 12 ? ? ? ? 3 non-polymer man ALPHA-D-MANNOSE 180.156 9 ? ? ? ? 4 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 7 ? ? ? ? 5 water nat water 18.015 61 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Neural cadherin, N-cadherin' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;DWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDRELIARFHLRAHA VDINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPN MFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDVI VANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQ STATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVL DRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETCETPEPNSINITALDYDIDPNAGPFAF DLPLSPVTIKRNWTINRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVHHHHHH ; _entity_poly.pdbx_seq_one_letter_code_can ;DWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDRELIARFHLRAHA VDINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPN MFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDVI VANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQ STATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVL DRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETCETPEPNSINITALDYDIDPNAGPFAF DLPLSPVTIKRNWTINRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVHHHHHH ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ASP n 1 2 TRP n 1 3 VAL n 1 4 ILE n 1 5 PRO n 1 6 PRO n 1 7 ILE n 1 8 ASN n 1 9 LEU n 1 10 PRO n 1 11 GLU n 1 12 ASN n 1 13 SER n 1 14 ARG n 1 15 GLY n 1 16 PRO n 1 17 PHE n 1 18 PRO n 1 19 GLN n 1 20 GLU n 1 21 LEU n 1 22 VAL n 1 23 ARG n 1 24 ILE n 1 25 ARG n 1 26 SER n 1 27 ASP n 1 28 ARG n 1 29 ASP n 1 30 LYS n 1 31 ASN n 1 32 LEU n 1 33 SER n 1 34 LEU n 1 35 ARG n 1 36 TYR n 1 37 SER n 1 38 VAL n 1 39 THR n 1 40 GLY n 1 41 PRO n 1 42 GLY n 1 43 ALA n 1 44 ASP n 1 45 GLN n 1 46 PRO n 1 47 PRO n 1 48 THR n 1 49 GLY n 1 50 ILE n 1 51 PHE n 1 52 ILE n 1 53 ILE n 1 54 ASN n 1 55 PRO n 1 56 ILE n 1 57 SER n 1 58 GLY n 1 59 GLN n 1 60 LEU n 1 61 SER n 1 62 VAL n 1 63 THR n 1 64 LYS n 1 65 PRO n 1 66 LEU n 1 67 ASP n 1 68 ARG n 1 69 GLU n 1 70 LEU n 1 71 ILE n 1 72 ALA n 1 73 ARG n 1 74 PHE n 1 75 HIS n 1 76 LEU n 1 77 ARG n 1 78 ALA n 1 79 HIS n 1 80 ALA n 1 81 VAL n 1 82 ASP n 1 83 ILE n 1 84 ASN n 1 85 GLY n 1 86 ASN n 1 87 GLN n 1 88 VAL n 1 89 GLU n 1 90 ASN n 1 91 PRO n 1 92 ILE n 1 93 ASP n 1 94 ILE n 1 95 VAL n 1 96 ILE n 1 97 ASN n 1 98 VAL n 1 99 ILE n 1 100 ASP n 1 101 MET n 1 102 ASN n 1 103 ASP n 1 104 ASN n 1 105 ARG n 1 106 PRO n 1 107 GLU n 1 108 PHE n 1 109 LEU n 1 110 HIS n 1 111 GLN n 1 112 VAL n 1 113 TRP n 1 114 ASN n 1 115 GLY n 1 116 SER n 1 117 VAL n 1 118 PRO n 1 119 GLU n 1 120 GLY n 1 121 SER n 1 122 LYS n 1 123 PRO n 1 124 GLY n 1 125 THR n 1 126 TYR n 1 127 VAL n 1 128 MET n 1 129 THR n 1 130 VAL n 1 131 THR n 1 132 ALA n 1 133 ILE n 1 134 ASP n 1 135 ALA n 1 136 ASP n 1 137 ASP n 1 138 PRO n 1 139 ASN n 1 140 ALA n 1 141 LEU n 1 142 ASN n 1 143 GLY n 1 144 MET n 1 145 LEU n 1 146 ARG n 1 147 TYR n 1 148 ARG n 1 149 ILE n 1 150 LEU n 1 151 SER n 1 152 GLN n 1 153 ALA n 1 154 PRO n 1 155 SER n 1 156 THR n 1 157 PRO n 1 158 SER n 1 159 PRO n 1 160 ASN n 1 161 MET n 1 162 PHE n 1 163 THR n 1 164 ILE n 1 165 ASN n 1 166 ASN n 1 167 GLU n 1 168 THR n 1 169 GLY n 1 170 ASP n 1 171 ILE n 1 172 ILE n 1 173 THR n 1 174 VAL n 1 175 ALA n 1 176 ALA n 1 177 GLY n 1 178 LEU n 1 179 ASP n 1 180 ARG n 1 181 GLU n 1 182 LYS n 1 183 VAL n 1 184 GLN n 1 185 GLN n 1 186 TYR n 1 187 THR n 1 188 LEU n 1 189 ILE n 1 190 ILE n 1 191 GLN n 1 192 ALA n 1 193 THR n 1 194 ASP n 1 195 MET n 1 196 GLU n 1 197 GLY n 1 198 ASN n 1 199 PRO n 1 200 THR n 1 201 TYR n 1 202 GLY n 1 203 LEU n 1 204 SER n 1 205 ASN n 1 206 THR n 1 207 ALA n 1 208 THR n 1 209 ALA n 1 210 VAL n 1 211 ILE n 1 212 THR n 1 213 VAL n 1 214 THR n 1 215 ASP n 1 216 VAL n 1 217 ASN n 1 218 ASP n 1 219 ASN n 1 220 PRO n 1 221 PRO n 1 222 GLU n 1 223 PHE n 1 224 THR n 1 225 ALA n 1 226 MET n 1 227 THR n 1 228 PHE n 1 229 TYR n 1 230 GLY n 1 231 GLU n 1 232 VAL n 1 233 PRO n 1 234 GLU n 1 235 ASN n 1 236 ARG n 1 237 VAL n 1 238 ASP n 1 239 VAL n 1 240 ILE n 1 241 VAL n 1 242 ALA n 1 243 ASN n 1 244 LEU n 1 245 THR n 1 246 VAL n 1 247 THR n 1 248 ASP n 1 249 LYS n 1 250 ASP n 1 251 GLN n 1 252 PRO n 1 253 HIS n 1 254 THR n 1 255 PRO n 1 256 ALA n 1 257 TRP n 1 258 ASN n 1 259 ALA n 1 260 ALA n 1 261 TYR n 1 262 ARG n 1 263 ILE n 1 264 SER n 1 265 GLY n 1 266 GLY n 1 267 ASP n 1 268 PRO n 1 269 THR n 1 270 GLY n 1 271 ARG n 1 272 PHE n 1 273 ALA n 1 274 ILE n 1 275 LEU n 1 276 THR n 1 277 ASP n 1 278 PRO n 1 279 ASN n 1 280 SER n 1 281 ASN n 1 282 ASP n 1 283 GLY n 1 284 LEU n 1 285 VAL n 1 286 THR n 1 287 VAL n 1 288 VAL n 1 289 LYS n 1 290 PRO n 1 291 ILE n 1 292 ASP n 1 293 PHE n 1 294 GLU n 1 295 THR n 1 296 ASN n 1 297 ARG n 1 298 MET n 1 299 PHE n 1 300 VAL n 1 301 LEU n 1 302 THR n 1 303 VAL n 1 304 ALA n 1 305 ALA n 1 306 GLU n 1 307 ASN n 1 308 GLN n 1 309 VAL n 1 310 PRO n 1 311 LEU n 1 312 ALA n 1 313 LYS n 1 314 GLY n 1 315 ILE n 1 316 GLN n 1 317 HIS n 1 318 PRO n 1 319 PRO n 1 320 GLN n 1 321 SER n 1 322 THR n 1 323 ALA n 1 324 THR n 1 325 VAL n 1 326 SER n 1 327 VAL n 1 328 THR n 1 329 VAL n 1 330 ILE n 1 331 ASP n 1 332 VAL n 1 333 ASN n 1 334 GLU n 1 335 ASN n 1 336 PRO n 1 337 TYR n 1 338 PHE n 1 339 ALA n 1 340 PRO n 1 341 ASN n 1 342 PRO n 1 343 LYS n 1 344 ILE n 1 345 ILE n 1 346 ARG n 1 347 GLN n 1 348 GLU n 1 349 GLU n 1 350 GLY n 1 351 LEU n 1 352 HIS n 1 353 ALA n 1 354 GLY n 1 355 THR n 1 356 MET n 1 357 LEU n 1 358 THR n 1 359 THR n 1 360 LEU n 1 361 THR n 1 362 ALA n 1 363 GLN n 1 364 ASP n 1 365 PRO n 1 366 ASP n 1 367 ARG n 1 368 TYR n 1 369 MET n 1 370 GLN n 1 371 GLN n 1 372 ASN n 1 373 ILE n 1 374 ARG n 1 375 TYR n 1 376 THR n 1 377 LYS n 1 378 LEU n 1 379 SER n 1 380 ASP n 1 381 PRO n 1 382 ALA n 1 383 ASN n 1 384 TRP n 1 385 LEU n 1 386 LYS n 1 387 ILE n 1 388 ASP n 1 389 PRO n 1 390 VAL n 1 391 ASN n 1 392 GLY n 1 393 GLN n 1 394 ILE n 1 395 THR n 1 396 THR n 1 397 ILE n 1 398 ALA n 1 399 VAL n 1 400 LEU n 1 401 ASP n 1 402 ARG n 1 403 GLU n 1 404 SER n 1 405 PRO n 1 406 ASN n 1 407 VAL n 1 408 LYS n 1 409 ASN n 1 410 ASN n 1 411 ILE n 1 412 TYR n 1 413 ASN n 1 414 ALA n 1 415 THR n 1 416 PHE n 1 417 LEU n 1 418 ALA n 1 419 SER n 1 420 ASP n 1 421 ASN n 1 422 GLY n 1 423 ILE n 1 424 PRO n 1 425 PRO n 1 426 MET n 1 427 SER n 1 428 GLY n 1 429 THR n 1 430 GLY n 1 431 THR n 1 432 LEU n 1 433 GLN n 1 434 ILE n 1 435 TYR n 1 436 LEU n 1 437 LEU n 1 438 ASP n 1 439 ILE n 1 440 ASN n 1 441 ASP n 1 442 ASN n 1 443 ALA n 1 444 PRO n 1 445 GLN n 1 446 VAL n 1 447 LEU n 1 448 PRO n 1 449 GLN n 1 450 GLU n 1 451 ALA n 1 452 GLU n 1 453 THR n 1 454 CYS n 1 455 GLU n 1 456 THR n 1 457 PRO n 1 458 GLU n 1 459 PRO n 1 460 ASN n 1 461 SER n 1 462 ILE n 1 463 ASN n 1 464 ILE n 1 465 THR n 1 466 ALA n 1 467 LEU n 1 468 ASP n 1 469 TYR n 1 470 ASP n 1 471 ILE n 1 472 ASP n 1 473 PRO n 1 474 ASN n 1 475 ALA n 1 476 GLY n 1 477 PRO n 1 478 PHE n 1 479 ALA n 1 480 PHE n 1 481 ASP n 1 482 LEU n 1 483 PRO n 1 484 LEU n 1 485 SER n 1 486 PRO n 1 487 VAL n 1 488 THR n 1 489 ILE n 1 490 LYS n 1 491 ARG n 1 492 ASN n 1 493 TRP n 1 494 THR n 1 495 ILE n 1 496 ASN n 1 497 ARG n 1 498 LEU n 1 499 ASN n 1 500 GLY n 1 501 ASP n 1 502 PHE n 1 503 ALA n 1 504 GLN n 1 505 LEU n 1 506 ASN n 1 507 LEU n 1 508 LYS n 1 509 ILE n 1 510 LYS n 1 511 PHE n 1 512 LEU n 1 513 GLU n 1 514 ALA n 1 515 GLY n 1 516 ILE n 1 517 TYR n 1 518 GLU n 1 519 VAL n 1 520 PRO n 1 521 ILE n 1 522 ILE n 1 523 ILE n 1 524 THR n 1 525 ASP n 1 526 SER n 1 527 GLY n 1 528 ASN n 1 529 PRO n 1 530 PRO n 1 531 LYS n 1 532 SER n 1 533 ASN n 1 534 ILE n 1 535 SER n 1 536 ILE n 1 537 LEU n 1 538 ARG n 1 539 VAL n 1 540 LYS n 1 541 VAL n 1 542 CYS n 1 543 GLN n 1 544 CYS n 1 545 ASP n 1 546 SER n 1 547 ASN n 1 548 GLY n 1 549 ASP n 1 550 CYS n 1 551 THR n 1 552 ASP n 1 553 VAL n 1 554 HIS n 1 555 HIS n 1 556 HIS n 1 557 HIS n 1 558 HIS n 1 559 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name mouse _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene Cdh2 _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Mus musculus' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 10090 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 9606 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell HEK293 _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type pCEP4 _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code CADH2_MOUSE _struct_ref.pdbx_db_accession P15116 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;DWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDRELIARFHLRAHA VDINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPN MFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDVI VANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQ STATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVL DRESPYVQNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETCETPEPNSINIAALDYDIDPNAGPFAF DLPLSPVTIKRNWTINRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTD ; _struct_ref.pdbx_align_begin 160 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 3Q2W _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 553 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession P15116 _struct_ref_seq.db_align_beg 160 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 712 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 1 _struct_ref_seq.pdbx_auth_seq_align_end 553 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3Q2W ASN A 406 ? UNP P15116 TYR 565 CONFLICT 406 1 1 3Q2W LYS A 408 ? UNP P15116 GLN 567 CONFLICT 408 2 1 3Q2W THR A 465 ? UNP P15116 ALA 624 CONFLICT 465 3 1 3Q2W HIS A 554 ? UNP P15116 ? ? 'EXPRESSION TAG' 554 4 1 3Q2W HIS A 555 ? UNP P15116 ? ? 'EXPRESSION TAG' 555 5 1 3Q2W HIS A 556 ? UNP P15116 ? ? 'EXPRESSION TAG' 556 6 1 3Q2W HIS A 557 ? UNP P15116 ? ? 'EXPRESSION TAG' 557 7 1 3Q2W HIS A 558 ? UNP P15116 ? ? 'EXPRESSION TAG' 558 8 1 3Q2W HIS A 559 ? UNP P15116 ? ? 'EXPRESSION TAG' 559 9 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CA non-polymer . 'CALCIUM ION' ? 'Ca 2' 40.078 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 3Q2W _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 5.44 _exptl_crystal.density_percent_sol 77.39 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 8.5 _exptl_crystal_grow.pdbx_details '25% PEG8000, 0.1M Tris, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'MAR CCD 165 mm' _diffrn_detector.pdbx_collection_date 2009-07-31 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'Si (111) crystal monochromator with vertical focusing mirror' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9793 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'NSLS BEAMLINE X4C' _diffrn_source.pdbx_synchrotron_site NSLS _diffrn_source.pdbx_synchrotron_beamline X4C _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.9793 # _reflns.entry_id 3Q2W _reflns.observed_criterion_sigma_I 1 _reflns.observed_criterion_sigma_F 1 _reflns.d_resolution_low 20 _reflns.d_resolution_high 3.2 _reflns.number_obs 21590 _reflns.number_all 24506 _reflns.percent_possible_obs 88.1 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI ? _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy ? _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 # _refine.entry_id 3Q2W _refine.ls_number_reflns_obs 20206 _refine.ls_number_reflns_all 21590 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.34 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 19.947 _refine.ls_d_res_high 3.200 _refine.ls_percent_reflns_obs 89.94 _refine.ls_R_factor_obs 0.2315 _refine.ls_R_factor_all 0.232 _refine.ls_R_factor_R_work 0.2295 _refine.ls_R_factor_R_free 0.2672 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.09 _refine.ls_number_reflns_R_free 1029 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean ? _refine.aniso_B[1][1] 17.3637 _refine.aniso_B[2][2] -14.0322 _refine.aniso_B[3][3] -3.3315 _refine.aniso_B[1][2] -0.0000 _refine.aniso_B[1][3] -0.0000 _refine.aniso_B[2][3] -0.0000 _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_ksol 0.236 _refine.solvent_model_param_bsol 0.796 _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_ls_cross_valid_method ? _refine.details ? _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details random _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.40 _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_overall_ESU_R ? _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 4171 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 209 _refine_hist.number_atoms_solvent 61 _refine_hist.number_atoms_total 4441 _refine_hist.d_res_high 3.200 _refine_hist.d_res_low 19.947 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function f_bond_d 0.007 ? ? 4473 'X-RAY DIFFRACTION' ? f_angle_d 1.176 ? ? 6137 'X-RAY DIFFRACTION' ? f_dihedral_angle_d 19.219 ? ? 1695 'X-RAY DIFFRACTION' ? f_chiral_restr 0.067 ? ? 749 'X-RAY DIFFRACTION' ? f_plane_restr 0.002 ? ? 796 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_all _refine_ls_shell.R_factor_all _refine_ls_shell.number_reflns_obs _refine_ls_shell.redundancy_reflns_obs _refine_ls_shell.pdbx_refine_id . 3.2001 3.3680 2180 0.2884 72.00 0.3492 . . 108 . . . . 'X-RAY DIFFRACTION' . 3.3680 3.5779 2376 0.2474 79.00 0.3200 . . 114 . . . . 'X-RAY DIFFRACTION' . 3.5779 3.8523 2552 0.2382 85.00 0.2666 . . 140 . . . . 'X-RAY DIFFRACTION' . 3.8523 4.2366 2880 0.2327 95.00 0.2828 . . 151 . . . . 'X-RAY DIFFRACTION' . 4.2366 4.8420 2970 0.2028 99.00 0.2289 . . 187 . . . . 'X-RAY DIFFRACTION' . 4.8420 6.0718 3047 0.2130 100.00 0.2453 . . 170 . . . . 'X-RAY DIFFRACTION' . 6.0718 19.9476 3172 0.2100 100.00 0.2343 . . 159 . . . . 'X-RAY DIFFRACTION' # _struct.entry_id 3Q2W _struct.title 'Crystal structure of mouse N-cadherin ectodomain' _struct.pdbx_descriptor Cadherin-2 _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3Q2W _struct_keywords.pdbx_keywords 'CELL ADHESION' _struct_keywords.text 'cadherin, cell adhesion, calcium binding' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 2 ? E N N 2 ? F N N 2 ? G N N 2 ? H N N 2 ? I N N 2 ? J N N 2 ? K N N 2 ? L N N 2 ? M N N 2 ? N N N 3 ? O N N 3 ? P N N 3 ? Q N N 3 ? R N N 3 ? S N N 3 ? T N N 3 ? U N N 3 ? V N N 3 ? W N N 4 ? X N N 4 ? Y N N 4 ? Z N N 4 ? AA N N 4 ? BA N N 4 ? CA N N 4 ? DA N N 5 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 SER A 26 ? ASN A 31 ? SER A 26 ASN A 31 5 ? 6 HELX_P HELX_P2 2 ALA A 140 ? MET A 144 ? ALA A 140 MET A 144 5 ? 5 HELX_P HELX_P3 3 ASP A 194 ? ASN A 198 ? ASP A 194 ASN A 198 1 ? 5 HELX_P HELX_P4 4 PRO A 318 ? GLN A 320 ? PRO A 318 GLN A 320 5 ? 3 HELX_P HELX_P5 5 PRO A 486 ? ASN A 492 ? PRO A 486 ASN A 492 1 ? 7 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order covale1 covale ? ? A ASN 166 ND2 ? ? ? 1_555 X NAG . C1 ? ? A ASN 166 A NAG 802 1_555 ? ? ? ? ? ? ? 1.439 ? covale2 covale ? ? AA NAG . O4 ? ? ? 1_555 BA NAG . C1 ? ? A NAG 805 A NAG 806 1_555 ? ? ? ? ? ? ? 1.444 ? covale3 covale ? ? A ASN 243 ND2 ? ? ? 1_555 Z NAG . C1 ? ? A ASN 243 A NAG 804 1_555 ? ? ? ? ? ? ? 1.446 ? covale4 covale ? ? A ASN 413 ND2 ? ? ? 1_555 AA NAG . C1 ? ? A ASN 413 A NAG 805 1_555 ? ? ? ? ? ? ? 1.447 ? covale5 covale ? ? X NAG . O4 ? ? ? 1_555 Y NAG . C1 ? ? A NAG 802 A NAG 803 1_555 ? ? ? ? ? ? ? 1.450 ? covale6 covale ? ? A ASN 114 ND2 ? ? ? 1_555 W NAG . C1 ? ? A ASN 114 A NAG 801 1_555 ? ? ? ? ? ? ? 1.450 ? covale7 covale ? ? A ASN 492 ND2 ? ? ? 1_555 CA NAG . C1 ? ? A ASN 492 A NAG 807 1_555 ? ? ? ? ? ? ? 1.454 ? metalc1 metalc ? ? A ASP 179 OD1 ? ? ? 1_555 G CA . CA ? ? A ASP 179 A CA 606 1_555 ? ? ? ? ? ? ? 1.923 ? metalc2 metalc ? ? A GLU 69 OE1 ? ? ? 1_555 B CA . CA ? ? A GLU 69 A CA 601 1_555 ? ? ? ? ? ? ? 2.141 ? metalc3 metalc ? ? A ASN 219 O ? ? ? 1_555 F CA . CA ? ? A ASN 219 A CA 605 1_555 ? ? ? ? ? ? ? 2.158 ? metalc4 metalc ? ? A GLU 294 OE2 ? ? ? 1_555 I CA . CA ? ? A GLU 294 A CA 608 1_555 ? ? ? ? ? ? ? 2.170 ? metalc5 metalc ? ? A GLU 234 OE1 ? ? ? 1_555 H CA . CA ? ? A GLU 234 A CA 607 1_555 ? ? ? ? ? ? ? 2.218 ? metalc6 metalc ? ? A ASP 525 OD1 ? ? ? 1_555 M CA . CA ? ? A ASP 525 A CA 612 1_555 ? ? ? ? ? ? ? 2.222 ? metalc7 metalc ? ? A ASP 218 OD1 ? ? ? 1_555 G CA . CA ? ? A ASP 218 A CA 606 1_555 ? ? ? ? ? ? ? 2.267 ? metalc8 metalc ? ? A ASP 103 OD2 ? ? ? 1_555 B CA . CA ? ? A ASP 103 A CA 601 1_555 ? ? ? ? ? ? ? 2.271 ? metalc9 metalc ? ? A ASN 102 OD1 ? ? ? 1_555 D CA . CA ? ? A ASN 102 A CA 603 1_555 ? ? ? ? ? ? ? 2.282 ? metalc10 metalc ? ? A GLU 11 OE2 ? ? ? 1_555 C CA . CA ? ? A GLU 11 A CA 602 1_555 ? ? ? ? ? ? ? 2.295 ? metalc11 metalc ? ? A ASP 218 OD2 ? ? ? 1_555 E CA . CA ? ? A ASP 218 A CA 604 1_555 ? ? ? ? ? ? ? 2.297 ? metalc12 metalc ? ? A ASP 103 OD1 ? ? ? 1_555 C CA . CA ? ? A ASP 103 A CA 602 1_555 ? ? ? ? ? ? ? 2.304 ? metalc13 metalc ? ? A ASP 215 OD2 ? ? ? 1_555 E CA . CA ? ? A ASP 215 A CA 604 1_555 ? ? ? ? ? ? ? 2.307 ? metalc14 metalc ? ? A ASP 438 OD1 ? ? ? 1_555 K CA . CA ? ? A ASP 438 A CA 610 1_555 ? ? ? ? ? ? ? 2.321 ? metalc15 metalc ? ? A ASP 67 OD1 ? ? ? 1_555 B CA . CA ? ? A ASP 67 A CA 601 1_555 ? ? ? ? ? ? ? 2.326 ? metalc16 metalc ? ? A ASP 136 OD2 ? ? ? 1_555 D CA . CA ? ? A ASP 136 A CA 603 1_555 ? ? ? ? ? ? ? 2.329 ? metalc17 metalc ? ? A GLU 181 OE2 ? ? ? 1_555 E CA . CA ? ? A GLU 181 A CA 604 1_555 ? ? ? ? ? ? ? 2.331 ? metalc18 metalc ? ? A ASP 401 OD1 ? ? ? 1_555 L CA . CA ? ? A ASP 401 A CA 611 1_555 ? ? ? ? ? ? ? 2.334 ? metalc19 metalc ? ? A MET 101 O ? ? ? 1_555 C CA . CA ? ? A MET 101 A CA 602 1_555 ? ? ? ? ? ? ? 2.337 ? metalc20 metalc ? ? A ASP 136 OD1 ? ? ? 1_555 C CA . CA ? ? A ASP 136 A CA 602 1_555 ? ? ? ? ? ? ? 2.340 ? metalc21 metalc ? ? A GLU 334 OE2 ? ? ? 1_555 I CA . CA ? ? A GLU 334 A CA 608 1_555 ? ? ? ? ? ? ? 2.350 ? metalc22 metalc ? ? A GLU 11 OE1 ? ? ? 1_555 B CA . CA ? ? A GLU 11 A CA 601 1_555 ? ? ? ? ? ? ? 2.356 ? metalc23 metalc ? ? A GLU 181 OE1 ? ? ? 1_555 G CA . CA ? ? A GLU 181 A CA 606 1_555 ? ? ? ? ? ? ? 2.356 ? metalc24 metalc ? ? A ALA 256 O ? ? ? 1_555 F CA . CA ? ? A ALA 256 A CA 605 1_555 ? ? ? ? ? ? ? 2.360 ? metalc25 metalc ? ? A ASP 100 OD1 ? ? ? 1_555 C CA . CA ? ? A ASP 100 A CA 602 1_555 ? ? ? ? ? ? ? 2.364 ? metalc26 metalc ? ? A GLU 349 OE2 ? ? ? 1_555 L CA . CA ? ? A GLU 349 A CA 611 1_555 ? ? ? ? ? ? ? 2.370 ? metalc27 metalc ? ? A ASP 194 OD2 ? ? ? 1_555 D CA . CA ? ? A ASP 194 A CA 603 1_555 ? ? ? ? ? ? ? 2.380 ? metalc28 metalc ? ? A ASN 217 OD1 ? ? ? 1_555 F CA . CA ? ? A ASN 217 A CA 605 1_555 ? ? ? ? ? ? ? 2.386 ? metalc29 metalc ? ? A ASP 134 OD1 ? ? ? 1_555 D CA . CA ? ? A ASP 134 A CA 603 1_555 ? ? ? ? ? ? ? 2.388 ? metalc30 metalc ? ? A ASN 442 O ? ? ? 1_555 M CA . CA ? ? A ASN 442 A CA 612 1_555 ? ? ? ? ? ? ? 2.403 ? metalc31 metalc ? ? A ILE 439 O ? ? ? 1_555 K CA . CA ? ? A ILE 439 A CA 610 1_555 ? ? ? ? ? ? ? 2.406 ? metalc32 metalc ? ? A ASN 307 OD1 ? ? ? 1_555 F CA . CA ? ? A ASN 307 A CA 605 1_555 ? ? ? ? ? ? ? 2.411 ? metalc33 metalc ? ? A GLU 119 OE2 ? ? ? 1_555 G CA . CA ? ? A GLU 119 A CA 606 1_555 ? ? ? ? ? ? ? 2.417 ? metalc34 metalc ? ? A ASN 104 O ? ? ? 1_555 D CA . CA ? ? A ASN 104 A CA 603 1_555 ? ? ? ? ? ? ? 2.418 ? metalc35 metalc ? ? A ASN 333 OD1 ? ? ? 1_555 J CA . CA ? ? A ASN 333 A CA 609 1_555 ? ? ? ? ? ? ? 2.418 ? metalc36 metalc ? ? A GLU 69 OE2 ? ? ? 1_555 C CA . CA ? ? A GLU 69 A CA 602 1_555 ? ? ? ? ? ? ? 2.426 ? metalc37 metalc ? ? A GLU 334 O ? ? ? 1_555 J CA . CA ? ? A GLU 334 A CA 609 1_555 ? ? ? ? ? ? ? 2.432 ? metalc38 metalc ? ? A GLU 294 OE1 ? ? ? 1_555 H CA . CA ? ? A GLU 294 A CA 607 1_555 ? ? ? ? ? ? ? 2.436 ? metalc39 metalc ? ? A ASN 440 OD1 ? ? ? 1_555 M CA . CA ? ? A ASN 440 A CA 612 1_555 ? ? ? ? ? ? ? 2.441 ? metalc40 metalc ? ? A ASN 142 O ? ? ? 1_555 D CA . CA ? ? A ASN 142 A CA 603 1_555 ? ? ? ? ? ? ? 2.442 ? metalc41 metalc ? ? A GLU 349 OE1 ? ? ? 1_555 K CA . CA ? ? A GLU 349 A CA 610 1_555 ? ? ? ? ? ? ? 2.455 ? metalc42 metalc ? ? A ASP 441 OD2 ? ? ? 1_555 K CA . CA ? ? A ASP 441 A CA 610 1_555 ? ? ? ? ? ? ? 2.507 ? metalc43 metalc ? ? A GLU 119 OE1 ? ? ? 1_555 E CA . CA ? ? A GLU 119 A CA 604 1_555 ? ? ? ? ? ? ? 2.510 ? metalc44 metalc ? ? A GLU 403 OE1 ? ? ? 1_555 L CA . CA ? ? A GLU 403 A CA 611 1_555 ? ? ? ? ? ? ? 2.514 ? metalc45 metalc ? ? A ASP 331 OD1 ? ? ? 1_555 I CA . CA ? ? A ASP 331 A CA 608 1_555 ? ? ? ? ? ? ? 2.522 ? metalc46 metalc ? ? A ASP 420 OD2 ? ? ? 1_555 J CA . CA ? ? A ASP 420 A CA 609 1_555 ? ? ? ? ? ? ? 2.547 ? metalc47 metalc ? ? A GLU 403 OE1 ? ? ? 1_555 K CA . CA ? ? A GLU 403 A CA 610 1_555 ? ? ? ? ? ? ? 2.571 ? metalc48 metalc ? ? A VAL 216 O ? ? ? 1_555 E CA . CA ? ? A VAL 216 A CA 604 1_555 ? ? ? ? ? ? ? 2.606 ? metalc49 metalc ? ? A ASP 250 OD2 ? ? ? 1_555 F CA . CA ? ? A ASP 250 A CA 605 1_555 ? ? ? ? ? ? ? 2.610 ? metalc50 metalc ? ? A GLU 334 OE1 ? ? ? 1_555 H CA . CA ? ? A GLU 334 A CA 607 1_555 ? ? ? ? ? ? ? 2.626 ? metalc51 metalc ? ? A ASP 292 OD1 ? ? ? 1_555 H CA . CA ? ? A ASP 292 A CA 607 1_555 ? ? ? ? ? ? ? 2.650 ? metalc52 metalc ? ? A GLU 69 OE1 ? ? ? 1_555 C CA . CA ? ? A GLU 69 A CA 602 1_555 ? ? ? ? ? ? ? 2.707 ? metalc53 metalc ? ? A ASP 248 OD2 ? ? ? 1_555 F CA . CA ? ? A ASP 248 A CA 605 1_555 ? ? ? ? ? ? ? 2.722 ? metalc54 metalc ? ? A ASP 470 OD2 ? ? ? 1_555 K CA . CA ? ? A ASP 470 A CA 610 1_555 ? ? ? ? ? ? ? 2.728 ? metalc55 metalc ? ? A ASP 248 OD1 ? ? ? 1_555 F CA . CA ? ? A ASP 248 A CA 605 1_555 ? ? ? ? ? ? ? 2.734 ? metalc56 metalc ? ? A ASP 364 OD2 ? ? ? 1_555 J CA . CA ? ? A ASP 364 A CA 609 1_555 ? ? ? ? ? ? ? 2.737 ? metalc57 metalc ? ? A ASP 470 OD1 ? ? ? 1_555 M CA . CA ? ? A ASP 470 A CA 612 1_555 ? ? ? ? ? ? ? 2.762 ? metalc58 metalc ? ? A ASP 468 OD2 ? ? ? 1_555 M CA . CA ? ? A ASP 468 A CA 612 1_555 ? ? ? ? ? ? ? 2.769 ? metalc59 metalc ? ? A ASP 468 OD1 ? ? ? 1_555 M CA . CA ? ? A ASP 468 A CA 612 1_555 ? ? ? ? ? ? ? 2.796 ? metalc60 metalc ? ? A VAL 332 O ? ? ? 1_555 I CA . CA ? ? A VAL 332 A CA 608 1_555 ? ? ? ? ? ? ? 2.812 ? metalc61 metalc ? ? A ASP 441 OD1 ? ? ? 1_555 L CA . CA ? ? A ASP 441 A CA 611 1_555 ? ? ? ? ? ? ? 2.849 ? metalc62 metalc ? ? A ASP 134 OD2 ? ? ? 1_555 D CA . CA ? ? A ASP 134 A CA 603 1_555 ? ? ? ? ? ? ? 2.864 ? metalc63 metalc ? ? A GLN 371 OE1 ? ? ? 1_555 J CA . CA ? ? A GLN 371 A CA 609 1_555 ? ? ? ? ? ? ? 2.902 ? metalc64 metalc ? ? A GLU 234 OE2 ? ? ? 1_555 I CA . CA ? ? A GLU 234 A CA 608 1_555 ? ? ? ? ? ? ? 2.944 ? metalc65 metalc ? ? A ASP 250 OD1 ? ? ? 1_555 E CA . CA ? ? A ASP 250 A CA 604 1_555 ? ? ? ? ? ? ? 2.968 ? metalc66 metalc ? ? A GLU 181 OE1 ? ? ? 1_555 E CA . CA ? ? A GLU 181 A CA 604 1_555 ? ? ? ? ? ? ? 3.027 ? metalc67 metalc ? ? A ASP 364 OD1 ? ? ? 1_555 J CA . CA ? ? A ASP 364 A CA 609 1_555 ? ? ? ? ? ? ? 3.033 ? metalc68 metalc ? ? A GLU 403 OE2 ? ? ? 1_555 K CA . CA ? ? A GLU 403 A CA 610 1_555 ? ? ? ? ? ? ? 3.038 ? metalc69 metalc ? ? A ASN 474 O ? ? ? 1_555 M CA . CA ? ? A ASN 474 A CA 612 1_555 ? ? ? ? ? ? ? 3.114 ? metalc70 metalc ? ? A GLU 234 OE1 ? ? ? 1_555 I CA . CA ? ? A GLU 234 A CA 608 1_555 ? ? ? ? ? ? ? 3.193 ? covale8 covale ? ? A THR 206 OG1 ? ? ? 1_555 N MAN . C1 ? ? A THR 206 A MAN 701 1_555 ? ? ? ? ? ? ? 1.430 ? covale9 covale ? ? A SER 427 OG ? ? ? 1_555 T MAN . C1 ? ? A SER 427 A MAN 708 1_555 ? ? ? ? ? ? ? 1.438 ? covale10 covale ? ? A THR 324 OG1 ? ? ? 1_555 R MAN . C1 ? ? A THR 324 A MAN 706 1_555 ? ? ? ? ? ? ? 1.439 ? covale11 covale ? ? A SER 326 OG ? ? ? 1_555 Q MAN . C1 ? ? A SER 326 A MAN 705 1_555 ? ? ? ? ? ? ? 1.442 ? covale12 covale ? ? A THR 429 OG1 ? ? ? 1_555 U MAN . C1 ? ? A THR 429 A MAN 709 1_555 ? ? ? ? ? ? ? 1.445 ? covale13 covale ? ? A THR 322 OG1 ? ? ? 1_555 S MAN . C1 ? ? A THR 322 A MAN 707 1_555 ? ? ? ? ? ? ? 1.445 ? covale14 covale ? ? A THR 431 OG1 ? ? ? 1_555 V MAN . C1 ? ? A THR 431 A MAN 710 1_555 ? ? ? ? ? ? ? 1.446 ? covale15 covale ? ? A THR 208 OG1 ? ? ? 1_555 O MAN . C1 ? ? A THR 208 A MAN 702 1_555 ? ? ? ? ? ? ? 1.448 ? covale16 covale ? ? A THR 131 OG1 ? ? ? 1_555 P MAN . C1 ? ? A THR 131 A MAN 703 1_555 ? ? ? ? ? ? ? 1.451 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 GLY 15 A . ? GLY 15 A PRO 16 A ? PRO 16 A 1 8.50 2 PHE 17 A . ? PHE 17 A PRO 18 A ? PRO 18 A 1 2.88 3 PRO 46 A . ? PRO 46 A PRO 47 A ? PRO 47 A 1 -1.30 4 ALA 153 A . ? ALA 153 A PRO 154 A ? PRO 154 A 1 -1.23 5 THR 156 A . ? THR 156 A PRO 157 A ? PRO 157 A 1 -0.89 6 ASP 472 A . ? ASP 472 A PRO 473 A ? PRO 473 A 1 2.23 7 SER 485 A . ? SER 485 A PRO 486 A ? PRO 486 A 1 7.22 8 ASN 528 A . ? ASN 528 A PRO 529 A ? PRO 529 A 1 -2.59 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 4 ? B ? 3 ? C ? 2 ? D ? 4 ? E ? 3 ? F ? 4 ? G ? 4 ? H ? 2 ? I ? 4 ? J ? 3 ? K ? 2 ? L ? 3 ? M ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel C 1 2 ? anti-parallel D 1 2 ? parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel G 1 2 ? parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel H 1 2 ? anti-parallel I 1 2 ? parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel K 1 2 ? anti-parallel L 1 2 ? anti-parallel L 2 3 ? anti-parallel M 1 2 ? anti-parallel M 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 ILE A 7 ? PRO A 10 ? ILE A 7 PRO A 10 A 2 GLN A 87 ? ILE A 99 ? GLN A 87 ILE A 99 A 3 ARG A 73 ? ASP A 82 ? ARG A 73 ASP A 82 A 4 LEU A 34 ? THR A 39 ? LEU A 34 THR A 39 B 1 GLN A 19 ? ARG A 23 ? GLN A 19 ARG A 23 B 2 GLN A 59 ? VAL A 62 ? GLN A 59 VAL A 62 B 3 PHE A 51 ? ILE A 53 ? PHE A 51 ILE A 53 C 1 GLU A 107 ? PHE A 108 ? GLU A 107 PHE A 108 C 2 ALA A 132 ? ILE A 133 ? ALA A 132 ILE A 133 D 1 VAL A 112 ? PRO A 118 ? VAL A 112 PRO A 118 D 2 SER A 204 ? THR A 214 ? SER A 204 THR A 214 D 3 GLN A 185 ? THR A 193 ? GLN A 185 THR A 193 D 4 ARG A 146 ? ALA A 153 ? ARG A 146 ALA A 153 E 1 TYR A 126 ? THR A 129 ? TYR A 126 THR A 129 E 2 ASP A 170 ? THR A 173 ? ASP A 170 THR A 173 E 3 PHE A 162 ? ILE A 164 ? PHE A 162 ILE A 164 F 1 GLU A 222 ? PHE A 223 ? GLU A 222 PHE A 223 F 2 VAL A 239 ? THR A 247 ? VAL A 239 THR A 247 F 3 ASP A 282 ? VAL A 287 ? ASP A 282 VAL A 287 F 4 PHE A 272 ? THR A 276 ? PHE A 272 THR A 276 G 1 THR A 227 ? PRO A 233 ? THR A 227 PRO A 233 G 2 THR A 322 ? ILE A 330 ? THR A 322 ILE A 330 G 3 MET A 298 ? ALA A 304 ? MET A 298 ALA A 304 G 4 ARG A 262 ? GLY A 265 ? ARG A 262 GLY A 265 H 1 TYR A 337 ? PHE A 338 ? TYR A 337 PHE A 338 H 2 ALA A 362 ? GLN A 363 ? ALA A 362 GLN A 363 I 1 PRO A 342 ? GLU A 348 ? PRO A 342 GLU A 348 I 2 SER A 427 ? LEU A 437 ? SER A 427 LEU A 437 I 3 ILE A 411 ? ASP A 420 ? ILE A 411 ASP A 420 I 4 ILE A 373 ? SER A 379 ? ILE A 373 SER A 379 J 1 MET A 356 ? THR A 359 ? MET A 356 THR A 359 J 2 GLN A 393 ? THR A 396 ? GLN A 393 THR A 396 J 3 LEU A 385 ? ILE A 387 ? LEU A 385 ILE A 387 K 1 GLN A 445 ? VAL A 446 ? GLN A 445 VAL A 446 K 2 ALA A 466 ? LEU A 467 ? ALA A 466 LEU A 467 L 1 ILE A 462 ? ILE A 464 ? ILE A 462 ILE A 464 L 2 ALA A 503 ? LEU A 507 ? ALA A 503 LEU A 507 L 3 TRP A 493 ? ARG A 497 ? TRP A 493 ARG A 497 M 1 ALA A 479 ? ASP A 481 ? ALA A 479 ASP A 481 M 2 GLY A 515 ? THR A 524 ? GLY A 515 THR A 524 M 3 SER A 532 ? VAL A 541 ? SER A 532 VAL A 541 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N LEU A 9 ? N LEU A 9 O ILE A 99 ? O ILE A 99 A 2 3 O ILE A 94 ? O ILE A 94 N LEU A 76 ? N LEU A 76 A 3 4 O HIS A 79 ? O HIS A 79 N SER A 37 ? N SER A 37 B 1 2 N VAL A 22 ? N VAL A 22 O LEU A 60 ? O LEU A 60 B 2 3 O SER A 61 ? O SER A 61 N ILE A 52 ? N ILE A 52 C 1 2 N GLU A 107 ? N GLU A 107 O ILE A 133 ? O ILE A 133 D 1 2 N TRP A 113 ? N TRP A 113 O THR A 208 ? O THR A 208 D 2 3 O ASN A 205 ? O ASN A 205 N ALA A 192 ? N ALA A 192 D 3 4 O ILE A 189 ? O ILE A 189 N LEU A 150 ? N LEU A 150 E 1 2 N MET A 128 ? N MET A 128 O ILE A 171 ? O ILE A 171 E 2 3 O ILE A 172 ? O ILE A 172 N THR A 163 ? N THR A 163 F 1 2 N GLU A 222 ? N GLU A 222 O THR A 247 ? O THR A 247 F 2 3 N VAL A 241 ? N VAL A 241 O VAL A 285 ? O VAL A 285 F 3 4 O THR A 286 ? O THR A 286 N ALA A 273 ? N ALA A 273 G 1 2 N PHE A 228 ? N PHE A 228 O SER A 326 ? O SER A 326 G 2 3 O VAL A 327 ? O VAL A 327 N PHE A 299 ? N PHE A 299 G 3 4 O ALA A 304 ? O ALA A 304 N ARG A 262 ? N ARG A 262 H 1 2 N TYR A 337 ? N TYR A 337 O GLN A 363 ? O GLN A 363 I 1 2 N GLN A 347 ? N GLN A 347 O TYR A 435 ? O TYR A 435 I 2 3 O LEU A 432 ? O LEU A 432 N ALA A 414 ? N ALA A 414 I 3 4 O LEU A 417 ? O LEU A 417 N THR A 376 ? N THR A 376 J 1 2 N LEU A 357 ? N LEU A 357 O ILE A 394 ? O ILE A 394 J 2 3 O THR A 395 ? O THR A 395 N LYS A 386 ? N LYS A 386 K 1 2 N GLN A 445 ? N GLN A 445 O LEU A 467 ? O LEU A 467 L 1 2 N ILE A 464 ? N ILE A 464 O ALA A 503 ? O ALA A 503 L 2 3 O GLN A 504 ? O GLN A 504 N ASN A 496 ? N ASN A 496 M 1 2 N ASP A 481 ? N ASP A 481 O ILE A 522 ? O ILE A 522 M 2 3 N TYR A 517 ? N TYR A 517 O VAL A 539 ? O VAL A 539 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE CA A 601' AC2 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 602' AC3 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 603' AC4 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 604' AC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 605' AC6 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE CA A 606' AC7 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE CA A 607' AC8 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 608' AC9 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 609' BC1 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 610' BC2 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE CA A 611' BC3 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 612' BC4 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE MAN A 701' BC5 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE MAN A 702' BC6 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE MAN A 703' BC7 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE MAN A 705' BC8 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE MAN A 706' BC9 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE MAN A 707' CC1 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE MAN A 708' CC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE MAN A 709' CC3 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE MAN A 710' CC4 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 801' CC5 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 802' CC6 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG A 803' CC7 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 804' CC8 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 805' CC9 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 806' DC1 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 807' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 GLU A 11 ? GLU A 11 . ? 1_555 ? 2 AC1 4 ASP A 67 ? ASP A 67 . ? 1_555 ? 3 AC1 4 GLU A 69 ? GLU A 69 . ? 1_555 ? 4 AC1 4 ASP A 103 ? ASP A 103 . ? 1_555 ? 5 AC2 6 GLU A 11 ? GLU A 11 . ? 1_555 ? 6 AC2 6 GLU A 69 ? GLU A 69 . ? 1_555 ? 7 AC2 6 ASP A 100 ? ASP A 100 . ? 1_555 ? 8 AC2 6 MET A 101 ? MET A 101 . ? 1_555 ? 9 AC2 6 ASP A 103 ? ASP A 103 . ? 1_555 ? 10 AC2 6 ASP A 136 ? ASP A 136 . ? 1_555 ? 11 AC3 6 ASN A 102 ? ASN A 102 . ? 1_555 ? 12 AC3 6 ASN A 104 ? ASN A 104 . ? 1_555 ? 13 AC3 6 ASP A 134 ? ASP A 134 . ? 1_555 ? 14 AC3 6 ASP A 136 ? ASP A 136 . ? 1_555 ? 15 AC3 6 ASN A 142 ? ASN A 142 . ? 1_555 ? 16 AC3 6 ASP A 194 ? ASP A 194 . ? 1_555 ? 17 AC4 6 GLU A 119 ? GLU A 119 . ? 1_555 ? 18 AC4 6 GLU A 181 ? GLU A 181 . ? 1_555 ? 19 AC4 6 ASP A 215 ? ASP A 215 . ? 1_555 ? 20 AC4 6 VAL A 216 ? VAL A 216 . ? 1_555 ? 21 AC4 6 ASP A 218 ? ASP A 218 . ? 1_555 ? 22 AC4 6 ASP A 250 ? ASP A 250 . ? 1_555 ? 23 AC5 6 ASN A 217 ? ASN A 217 . ? 1_555 ? 24 AC5 6 ASN A 219 ? ASN A 219 . ? 1_555 ? 25 AC5 6 ASP A 248 ? ASP A 248 . ? 1_555 ? 26 AC5 6 ASP A 250 ? ASP A 250 . ? 1_555 ? 27 AC5 6 ALA A 256 ? ALA A 256 . ? 1_555 ? 28 AC5 6 ASN A 307 ? ASN A 307 . ? 1_555 ? 29 AC6 4 GLU A 119 ? GLU A 119 . ? 1_555 ? 30 AC6 4 ASP A 179 ? ASP A 179 . ? 1_555 ? 31 AC6 4 GLU A 181 ? GLU A 181 . ? 1_555 ? 32 AC6 4 ASP A 218 ? ASP A 218 . ? 1_555 ? 33 AC7 4 GLU A 234 ? GLU A 234 . ? 1_555 ? 34 AC7 4 ASP A 292 ? ASP A 292 . ? 1_555 ? 35 AC7 4 GLU A 294 ? GLU A 294 . ? 1_555 ? 36 AC7 4 GLU A 334 ? GLU A 334 . ? 1_555 ? 37 AC8 6 GLU A 234 ? GLU A 234 . ? 1_555 ? 38 AC8 6 GLU A 294 ? GLU A 294 . ? 1_555 ? 39 AC8 6 ASP A 331 ? ASP A 331 . ? 1_555 ? 40 AC8 6 VAL A 332 ? VAL A 332 . ? 1_555 ? 41 AC8 6 GLU A 334 ? GLU A 334 . ? 1_555 ? 42 AC8 6 ASP A 366 ? ASP A 366 . ? 1_555 ? 43 AC9 6 ASN A 333 ? ASN A 333 . ? 1_555 ? 44 AC9 6 GLU A 334 ? GLU A 334 . ? 1_555 ? 45 AC9 6 ASP A 364 ? ASP A 364 . ? 1_555 ? 46 AC9 6 ASP A 366 ? ASP A 366 . ? 1_555 ? 47 AC9 6 GLN A 371 ? GLN A 371 . ? 1_555 ? 48 AC9 6 ASP A 420 ? ASP A 420 . ? 1_555 ? 49 BC1 6 GLU A 349 ? GLU A 349 . ? 1_555 ? 50 BC1 6 GLU A 403 ? GLU A 403 . ? 1_555 ? 51 BC1 6 ASP A 438 ? ASP A 438 . ? 1_555 ? 52 BC1 6 ILE A 439 ? ILE A 439 . ? 1_555 ? 53 BC1 6 ASP A 441 ? ASP A 441 . ? 1_555 ? 54 BC1 6 ASP A 470 ? ASP A 470 . ? 1_555 ? 55 BC2 4 GLU A 349 ? GLU A 349 . ? 1_555 ? 56 BC2 4 ASP A 401 ? ASP A 401 . ? 1_555 ? 57 BC2 4 GLU A 403 ? GLU A 403 . ? 1_555 ? 58 BC2 4 ASP A 441 ? ASP A 441 . ? 1_555 ? 59 BC3 6 ASN A 440 ? ASN A 440 . ? 1_555 ? 60 BC3 6 ASN A 442 ? ASN A 442 . ? 1_555 ? 61 BC3 6 ASP A 468 ? ASP A 468 . ? 1_555 ? 62 BC3 6 ASP A 470 ? ASP A 470 . ? 1_555 ? 63 BC3 6 ASN A 474 ? ASN A 474 . ? 1_555 ? 64 BC3 6 ASP A 525 ? ASP A 525 . ? 1_555 ? 65 BC4 5 ILE A 189 ? ILE A 189 . ? 1_555 ? 66 BC4 5 THR A 206 ? THR A 206 . ? 1_555 ? 67 BC4 5 SER A 532 ? SER A 532 . ? 3_545 ? 68 BC4 5 ASN A 533 ? ASN A 533 . ? 3_545 ? 69 BC4 5 MAN O . ? MAN A 702 . ? 1_555 ? 70 BC5 4 GLN A 111 ? GLN A 111 . ? 1_555 ? 71 BC5 4 VAL A 112 ? VAL A 112 . ? 1_555 ? 72 BC5 4 THR A 208 ? THR A 208 . ? 1_555 ? 73 BC5 4 MAN N . ? MAN A 701 . ? 1_555 ? 74 BC6 3 LEU A 109 ? LEU A 109 . ? 1_555 ? 75 BC6 3 THR A 129 ? THR A 129 . ? 1_555 ? 76 BC6 3 THR A 131 ? THR A 131 . ? 1_555 ? 77 BC7 3 TYR A 229 ? TYR A 229 . ? 1_555 ? 78 BC7 3 VAL A 300 ? VAL A 300 . ? 1_555 ? 79 BC7 3 SER A 326 ? SER A 326 . ? 1_555 ? 80 BC8 2 THR A 227 ? THR A 227 . ? 1_555 ? 81 BC8 2 THR A 324 ? THR A 324 . ? 1_555 ? 82 BC9 3 HIS A 317 ? HIS A 317 . ? 1_555 ? 83 BC9 3 PRO A 318 ? PRO A 318 . ? 1_555 ? 84 BC9 3 THR A 322 ? THR A 322 . ? 1_555 ? 85 CC1 2 SER A 427 ? SER A 427 . ? 1_555 ? 86 CC1 2 MAN U . ? MAN A 709 . ? 1_555 ? 87 CC2 3 THR A 429 ? THR A 429 . ? 1_555 ? 88 CC2 3 MAN T . ? MAN A 708 . ? 1_555 ? 89 CC2 3 MAN V . ? MAN A 710 . ? 1_555 ? 90 CC3 3 THR A 429 ? THR A 429 . ? 1_555 ? 91 CC3 3 THR A 431 ? THR A 431 . ? 1_555 ? 92 CC3 3 MAN U . ? MAN A 709 . ? 1_555 ? 93 CC4 2 VAL A 112 ? VAL A 112 . ? 1_555 ? 94 CC4 2 ASN A 114 ? ASN A 114 . ? 1_555 ? 95 CC5 3 ASN A 84 ? ASN A 84 . ? 5_455 ? 96 CC5 3 ASN A 166 ? ASN A 166 . ? 1_555 ? 97 CC5 3 NAG Y . ? NAG A 803 . ? 1_555 ? 98 CC6 1 NAG X . ? NAG A 802 . ? 1_555 ? 99 CC7 2 ASN A 243 ? ASN A 243 . ? 1_555 ? 100 CC7 2 ASP A 282 ? ASP A 282 . ? 1_555 ? 101 CC8 5 ASN A 409 ? ASN A 409 . ? 1_555 ? 102 CC8 5 ILE A 411 ? ILE A 411 . ? 1_555 ? 103 CC8 5 ASN A 413 ? ASN A 413 . ? 1_555 ? 104 CC8 5 GLN A 433 ? GLN A 433 . ? 1_555 ? 105 CC8 5 NAG BA . ? NAG A 806 . ? 1_555 ? 106 CC9 2 ASN A 409 ? ASN A 409 . ? 1_555 ? 107 CC9 2 NAG AA . ? NAG A 805 . ? 1_555 ? 108 DC1 3 ASN A 492 ? ASN A 492 . ? 1_555 ? 109 DC1 3 TRP A 493 ? TRP A 493 . ? 1_555 ? 110 DC1 3 GLU A 518 ? GLU A 518 . ? 1_555 ? # _database_PDB_matrix.entry_id 3Q2W _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 3Q2W _atom_sites.fract_transf_matrix[1][1] 0.010944 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.008957 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.003815 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C CA N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ASP A 1 1 ? 51.988 6.333 0.217 1.00 21.74 ? 1 ASP A N 1 ATOM 2 C CA . ASP A 1 1 ? 51.048 5.213 0.511 1.00 21.09 ? 1 ASP A CA 1 ATOM 3 C C . ASP A 1 1 ? 49.593 5.535 0.185 1.00 15.62 ? 1 ASP A C 1 ATOM 4 O O . ASP A 1 1 ? 49.003 6.466 0.737 1.00 14.65 ? 1 ASP A O 1 ATOM 5 C CB . ASP A 1 1 ? 51.173 4.773 1.973 1.00 27.50 ? 1 ASP A CB 1 ATOM 6 C CG . ASP A 1 1 ? 52.326 3.793 2.202 1.00 38.78 ? 1 ASP A CG 1 ATOM 7 O OD1 . ASP A 1 1 ? 53.183 3.611 1.298 1.00 30.91 ? 1 ASP A OD1 1 ATOM 8 O OD2 . ASP A 1 1 ? 52.369 3.196 3.303 1.00 47.80 ? 1 ASP A OD2 1 ATOM 9 N N . TRP A 1 2 ? 49.031 4.750 -0.728 1.00 15.27 ? 2 TRP A N 1 ATOM 10 C CA . TRP A 1 2 ? 47.608 4.784 -1.011 1.00 11.34 ? 2 TRP A CA 1 ATOM 11 C C . TRP A 1 2 ? 46.849 4.402 0.246 1.00 11.19 ? 2 TRP A C 1 ATOM 12 O O . TRP A 1 2 ? 47.272 3.520 0.995 1.00 12.93 ? 2 TRP A O 1 ATOM 13 C CB . TRP A 1 2 ? 47.274 3.791 -2.109 1.00 10.03 ? 2 TRP A CB 1 ATOM 14 C CG . TRP A 1 2 ? 47.585 4.255 -3.489 1.00 11.77 ? 2 TRP A CG 1 ATOM 15 C CD1 . TRP A 1 2 ? 48.605 3.828 -4.285 1.00 13.66 ? 2 TRP A CD1 1 ATOM 16 C CD2 . TRP A 1 2 ? 46.850 5.215 -4.255 1.00 11.74 ? 2 TRP A CD2 1 ATOM 17 N NE1 . TRP A 1 2 ? 48.556 4.467 -5.500 1.00 14.64 ? 2 TRP A NE1 1 ATOM 18 C CE2 . TRP A 1 2 ? 47.491 5.328 -5.506 1.00 11.13 ? 2 TRP A CE2 1 ATOM 19 C CE3 . TRP A 1 2 ? 45.716 5.994 -4.003 1.00 11.92 ? 2 TRP A CE3 1 ATOM 20 C CZ2 . TRP A 1 2 ? 47.037 6.184 -6.505 1.00 9.98 ? 2 TRP A CZ2 1 ATOM 21 C CZ3 . TRP A 1 2 ? 45.267 6.848 -4.996 1.00 13.76 ? 2 TRP A CZ3 1 ATOM 22 C CH2 . TRP A 1 2 ? 45.930 6.936 -6.234 1.00 10.96 ? 2 TRP A CH2 1 ATOM 23 N N . VAL A 1 3 ? 45.724 5.064 0.470 1.00 12.33 ? 3 VAL A N 1 ATOM 24 C CA . VAL A 1 3 ? 44.974 4.909 1.708 1.00 11.63 ? 3 VAL A CA 1 ATOM 25 C C . VAL A 1 3 ? 43.721 4.098 1.434 1.00 9.22 ? 3 VAL A C 1 ATOM 26 O O . VAL A 1 3 ? 42.923 4.475 0.579 1.00 11.07 ? 3 VAL A O 1 ATOM 27 C CB . VAL A 1 3 ? 44.601 6.296 2.300 1.00 10.04 ? 3 VAL A CB 1 ATOM 28 C CG1 . VAL A 1 3 ? 43.706 6.160 3.518 1.00 12.17 ? 3 VAL A CG1 1 ATOM 29 C CG2 . VAL A 1 3 ? 45.853 7.075 2.653 1.00 11.37 ? 3 VAL A CG2 1 ATOM 30 N N . ILE A 1 4 ? 43.547 2.992 2.153 1.00 9.54 ? 4 ILE A N 1 ATOM 31 C CA . ILE A 1 4 ? 42.329 2.184 2.021 1.00 12.05 ? 4 ILE A CA 1 ATOM 32 C C . ILE A 1 4 ? 41.104 3.075 2.217 1.00 10.48 ? 4 ILE A C 1 ATOM 33 O O . ILE A 1 4 ? 41.002 3.788 3.217 1.00 9.91 ? 4 ILE A O 1 ATOM 34 C CB . ILE A 1 4 ? 42.297 0.955 2.992 1.00 11.78 ? 4 ILE A CB 1 ATOM 35 C CG1 . ILE A 1 4 ? 43.124 -0.207 2.438 1.00 9.06 ? 4 ILE A CG1 1 ATOM 36 C CG2 . ILE A 1 4 ? 40.884 0.428 3.178 1.00 8.63 ? 4 ILE A CG2 1 ATOM 37 C CD1 . ILE A 1 4 ? 44.595 -0.184 2.824 1.00 10.23 ? 4 ILE A CD1 1 ATOM 38 N N . PRO A 1 5 ? 40.181 3.047 1.249 1.00 9.88 ? 5 PRO A N 1 ATOM 39 C CA . PRO A 1 5 ? 39.019 3.918 1.310 1.00 11.09 ? 5 PRO A CA 1 ATOM 40 C C . PRO A 1 5 ? 38.221 3.644 2.569 1.00 10.37 ? 5 PRO A C 1 ATOM 41 O O . PRO A 1 5 ? 38.104 2.493 2.972 1.00 10.85 ? 5 PRO A O 1 ATOM 42 C CB . PRO A 1 5 ? 38.210 3.513 0.077 1.00 14.66 ? 5 PRO A CB 1 ATOM 43 C CG . PRO A 1 5 ? 39.184 2.856 -0.827 1.00 11.62 ? 5 PRO A CG 1 ATOM 44 C CD . PRO A 1 5 ? 40.169 2.188 0.054 1.00 9.82 ? 5 PRO A CD 1 ATOM 45 N N . PRO A 1 6 ? 37.705 4.699 3.212 1.00 10.10 ? 6 PRO A N 1 ATOM 46 C CA . PRO A 1 6 ? 36.853 4.518 4.386 1.00 12.18 ? 6 PRO A CA 1 ATOM 47 C C . PRO A 1 6 ? 35.564 3.798 4.030 1.00 12.94 ? 6 PRO A C 1 ATOM 48 O O . PRO A 1 6 ? 35.152 3.805 2.869 1.00 14.76 ? 6 PRO A O 1 ATOM 49 C CB . PRO A 1 6 ? 36.553 5.953 4.829 1.00 12.77 ? 6 PRO A CB 1 ATOM 50 C CG . PRO A 1 6 ? 37.648 6.783 4.222 1.00 12.62 ? 6 PRO A CG 1 ATOM 51 C CD . PRO A 1 6 ? 37.917 6.123 2.906 1.00 11.61 ? 6 PRO A CD 1 ATOM 52 N N . ILE A 1 7 ? 34.952 3.161 5.019 1.00 10.90 ? 7 ILE A N 1 ATOM 53 C CA . ILE A 1 7 ? 33.697 2.457 4.809 1.00 10.93 ? 7 ILE A CA 1 ATOM 54 C C . ILE A 1 7 ? 32.587 3.341 5.334 1.00 12.25 ? 7 ILE A C 1 ATOM 55 O O . ILE A 1 7 ? 32.648 3.807 6.470 1.00 15.75 ? 7 ILE A O 1 ATOM 56 C CB . ILE A 1 7 ? 33.678 1.110 5.542 1.00 9.95 ? 7 ILE A CB 1 ATOM 57 C CG1 . ILE A 1 7 ? 34.861 0.255 5.099 1.00 10.68 ? 7 ILE A CG1 1 ATOM 58 C CG2 . ILE A 1 7 ? 32.364 0.384 5.293 1.00 9.98 ? 7 ILE A CG2 1 ATOM 59 C CD1 . ILE A 1 7 ? 35.401 -0.615 6.194 1.00 10.17 ? 7 ILE A CD1 1 ATOM 60 N N . ASN A 1 8 ? 31.574 3.571 4.513 1.00 12.29 ? 8 ASN A N 1 ATOM 61 C CA . ASN A 1 8 ? 30.550 4.534 4.861 1.00 11.48 ? 8 ASN A CA 1 ATOM 62 C C . ASN A 1 8 ? 29.207 3.895 5.167 1.00 12.91 ? 8 ASN A C 1 ATOM 63 O O . ASN A 1 8 ? 28.426 3.594 4.262 1.00 13.31 ? 8 ASN A O 1 ATOM 64 C CB . ASN A 1 8 ? 30.453 5.596 3.769 1.00 12.82 ? 8 ASN A CB 1 ATOM 65 C CG . ASN A 1 8 ? 31.732 6.401 3.639 1.00 15.64 ? 8 ASN A CG 1 ATOM 66 O OD1 . ASN A 1 8 ? 32.429 6.635 4.630 1.00 14.34 ? 8 ASN A OD1 1 ATOM 67 N ND2 . ASN A 1 8 ? 32.055 6.821 2.419 1.00 16.16 ? 8 ASN A ND2 1 ATOM 68 N N . LEU A 1 9 ? 28.950 3.698 6.457 1.00 11.33 ? 9 LEU A N 1 ATOM 69 C CA . LEU A 1 9 ? 27.766 2.981 6.917 1.00 12.46 ? 9 LEU A CA 1 ATOM 70 C C . LEU A 1 9 ? 26.728 3.893 7.536 1.00 14.85 ? 9 LEU A C 1 ATOM 71 O O . LEU A 1 9 ? 27.060 4.705 8.393 1.00 16.39 ? 9 LEU A O 1 ATOM 72 C CB . LEU A 1 9 ? 28.150 1.931 7.956 1.00 11.85 ? 9 LEU A CB 1 ATOM 73 C CG . LEU A 1 9 ? 29.160 0.869 7.549 1.00 14.81 ? 9 LEU A CG 1 ATOM 74 C CD1 . LEU A 1 9 ? 29.356 -0.092 8.706 1.00 13.05 ? 9 LEU A CD1 1 ATOM 75 C CD2 . LEU A 1 9 ? 28.706 0.139 6.280 1.00 15.99 ? 9 LEU A CD2 1 ATOM 76 N N . PRO A 1 10 ? 25.458 3.743 7.125 1.00 13.25 ? 10 PRO A N 1 ATOM 77 C CA . PRO A 1 10 ? 24.381 4.434 7.818 1.00 14.34 ? 10 PRO A CA 1 ATOM 78 C C . PRO A 1 10 ? 24.153 3.798 9.178 1.00 12.67 ? 10 PRO A C 1 ATOM 79 O O . PRO A 1 10 ? 24.263 2.582 9.305 1.00 15.68 ? 10 PRO A O 1 ATOM 80 C CB . PRO A 1 10 ? 23.164 4.179 6.922 1.00 13.56 ? 10 PRO A CB 1 ATOM 81 C CG . PRO A 1 10 ? 23.708 3.643 5.646 1.00 13.28 ? 10 PRO A CG 1 ATOM 82 C CD . PRO A 1 10 ? 24.955 2.937 6.006 1.00 10.92 ? 10 PRO A CD 1 ATOM 83 N N . GLU A 1 11 ? 23.851 4.611 10.186 1.00 12.40 ? 11 GLU A N 1 ATOM 84 C CA . GLU A 1 11 ? 23.454 4.090 11.496 1.00 14.62 ? 11 GLU A CA 1 ATOM 85 C C . GLU A 1 11 ? 22.102 3.378 11.397 1.00 20.70 ? 11 GLU A C 1 ATOM 86 O O . GLU A 1 11 ? 21.452 3.406 10.346 1.00 21.52 ? 11 GLU A O 1 ATOM 87 C CB . GLU A 1 11 ? 23.405 5.199 12.551 1.00 13.52 ? 11 GLU A CB 1 ATOM 88 C CG . GLU A 1 11 ? 22.498 6.367 12.198 1.00 16.70 ? 11 GLU A CG 1 ATOM 89 C CD . GLU A 1 11 ? 22.106 7.228 13.395 1.00 23.97 ? 11 GLU A CD 1 ATOM 90 O OE1 . GLU A 1 11 ? 22.112 6.733 14.550 1.00 24.24 ? 11 GLU A OE1 1 ATOM 91 O OE2 . GLU A 1 11 ? 21.769 8.414 13.175 1.00 24.38 ? 11 GLU A OE2 1 ATOM 92 N N . ASN A 1 12 ? 21.695 2.729 12.486 1.00 19.98 ? 12 ASN A N 1 ATOM 93 C CA . ASN A 1 12 ? 20.428 2.002 12.544 1.00 19.14 ? 12 ASN A CA 1 ATOM 94 C C . ASN A 1 12 ? 20.213 1.053 11.362 1.00 24.66 ? 12 ASN A C 1 ATOM 95 O O . ASN A 1 12 ? 19.168 1.095 10.706 1.00 25.85 ? 12 ASN A O 1 ATOM 96 C CB . ASN A 1 12 ? 19.253 2.975 12.667 1.00 18.67 ? 12 ASN A CB 1 ATOM 97 C CG . ASN A 1 12 ? 19.443 3.983 13.777 1.00 24.44 ? 12 ASN A CG 1 ATOM 98 O OD1 . ASN A 1 12 ? 20.258 3.792 14.681 1.00 28.93 ? 12 ASN A OD1 1 ATOM 99 N ND2 . ASN A 1 12 ? 18.686 5.070 13.716 1.00 30.76 ? 12 ASN A ND2 1 ATOM 100 N N . SER A 1 13 ? 21.211 0.213 11.091 1.00 23.88 ? 13 SER A N 1 ATOM 101 C CA . SER A 1 13 ? 21.078 -0.841 10.085 1.00 27.32 ? 13 SER A CA 1 ATOM 102 C C . SER A 1 13 ? 20.137 -1.935 10.578 1.00 30.58 ? 13 SER A C 1 ATOM 103 O O . SER A 1 13 ? 20.107 -2.252 11.770 1.00 29.63 ? 13 SER A O 1 ATOM 104 C CB . SER A 1 13 ? 22.442 -1.445 9.747 1.00 32.05 ? 13 SER A CB 1 ATOM 105 O OG . SER A 1 13 ? 22.300 -2.677 9.052 1.00 33.33 ? 13 SER A OG 1 ATOM 106 N N . ARG A 1 14 ? 19.386 -2.524 9.653 1.00 32.78 ? 14 ARG A N 1 ATOM 107 C CA . ARG A 1 14 ? 18.460 -3.600 9.989 1.00 38.07 ? 14 ARG A CA 1 ATOM 108 C C . ARG A 1 14 ? 19.098 -4.974 9.794 1.00 38.91 ? 14 ARG A C 1 ATOM 109 O O . ARG A 1 14 ? 18.515 -5.995 10.157 1.00 36.23 ? 14 ARG A O 1 ATOM 110 C CB . ARG A 1 14 ? 17.184 -3.490 9.151 1.00 50.06 ? 14 ARG A CB 1 ATOM 111 C CG . ARG A 1 14 ? 16.128 -2.573 9.746 1.00 62.27 ? 14 ARG A CG 1 ATOM 112 C CD . ARG A 1 14 ? 14.760 -2.839 9.139 1.00 81.10 ? 14 ARG A CD 1 ATOM 113 N NE . ARG A 1 14 ? 13.689 -2.689 10.120 1.00 97.06 ? 14 ARG A NE 1 ATOM 114 C CZ . ARG A 1 14 ? 13.104 -3.704 10.748 1.00 104.48 ? 14 ARG A CZ 1 ATOM 115 N NH1 . ARG A 1 14 ? 13.487 -4.949 10.500 1.00 98.79 ? 14 ARG A NH1 1 ATOM 116 N NH2 . ARG A 1 14 ? 12.136 -3.474 11.625 1.00 102.51 ? 14 ARG A NH2 1 ATOM 117 N N . GLY A 1 15 ? 20.297 -4.993 9.219 1.00 37.70 ? 15 GLY A N 1 ATOM 118 C CA . GLY A 1 15 ? 21.010 -6.240 8.976 1.00 34.57 ? 15 GLY A CA 1 ATOM 119 C C . GLY A 1 15 ? 20.436 -7.042 7.820 1.00 32.97 ? 15 GLY A C 1 ATOM 120 O O . GLY A 1 15 ? 19.986 -6.463 6.835 1.00 32.98 ? 15 GLY A O 1 ATOM 121 N N . PRO A 1 16 ? 20.419 -8.383 7.945 1.00 30.91 ? 16 PRO A N 1 ATOM 122 C CA . PRO A 1 16 ? 20.738 -9.146 9.152 1.00 27.85 ? 16 PRO A CA 1 ATOM 123 C C . PRO A 1 16 ? 22.234 -9.246 9.439 1.00 25.87 ? 16 PRO A C 1 ATOM 124 O O . PRO A 1 16 ? 23.054 -9.214 8.518 1.00 25.24 ? 16 PRO A O 1 ATOM 125 C CB . PRO A 1 16 ? 20.171 -10.524 8.841 1.00 26.15 ? 16 PRO A CB 1 ATOM 126 C CG . PRO A 1 16 ? 20.309 -10.641 7.365 1.00 30.06 ? 16 PRO A CG 1 ATOM 127 C CD . PRO A 1 16 ? 20.082 -9.265 6.814 1.00 26.43 ? 16 PRO A CD 1 ATOM 128 N N . PHE A 1 17 ? 22.565 -9.364 10.718 1.00 21.76 ? 17 PHE A N 1 ATOM 129 C CA . PHE A 1 17 ? 23.944 -9.434 11.172 1.00 23.76 ? 17 PHE A CA 1 ATOM 130 C C . PHE A 1 17 ? 24.356 -10.889 11.392 1.00 26.29 ? 17 PHE A C 1 ATOM 131 O O . PHE A 1 17 ? 23.504 -11.716 11.726 1.00 29.22 ? 17 PHE A O 1 ATOM 132 C CB . PHE A 1 17 ? 24.101 -8.635 12.466 1.00 24.73 ? 17 PHE A CB 1 ATOM 133 C CG . PHE A 1 17 ? 23.669 -7.199 12.349 1.00 26.68 ? 17 PHE A CG 1 ATOM 134 C CD1 . PHE A 1 17 ? 24.541 -6.233 11.854 1.00 28.87 ? 17 PHE A CD1 1 ATOM 135 C CD2 . PHE A 1 17 ? 22.389 -6.812 12.729 1.00 28.31 ? 17 PHE A CD2 1 ATOM 136 C CE1 . PHE A 1 17 ? 24.143 -4.905 11.734 1.00 26.26 ? 17 PHE A CE1 1 ATOM 137 C CE2 . PHE A 1 17 ? 21.982 -5.487 12.613 1.00 29.44 ? 17 PHE A CE2 1 ATOM 138 C CZ . PHE A 1 17 ? 22.862 -4.532 12.113 1.00 27.60 ? 17 PHE A CZ 1 ATOM 139 N N . PRO A 1 18 ? 25.659 -11.213 11.225 1.00 23.34 ? 18 PRO A N 1 ATOM 140 C CA . PRO A 1 18 ? 26.804 -10.359 10.907 1.00 24.55 ? 18 PRO A CA 1 ATOM 141 C C . PRO A 1 18 ? 26.775 -9.864 9.473 1.00 22.75 ? 18 PRO A C 1 ATOM 142 O O . PRO A 1 18 ? 26.851 -10.662 8.541 1.00 31.26 ? 18 PRO A O 1 ATOM 143 C CB . PRO A 1 18 ? 28.011 -11.292 11.109 1.00 21.65 ? 18 PRO A CB 1 ATOM 144 C CG . PRO A 1 18 ? 27.491 -12.465 11.845 1.00 23.54 ? 18 PRO A CG 1 ATOM 145 C CD . PRO A 1 18 ? 26.088 -12.611 11.373 1.00 27.82 ? 18 PRO A CD 1 ATOM 146 N N . GLN A 1 19 ? 26.661 -8.553 9.307 1.00 19.85 ? 19 GLN A N 1 ATOM 147 C CA . GLN A 1 19 ? 26.580 -7.948 7.990 1.00 23.07 ? 19 GLN A CA 1 ATOM 148 C C . GLN A 1 19 ? 27.983 -7.684 7.483 1.00 21.09 ? 19 GLN A C 1 ATOM 149 O O . GLN A 1 19 ? 28.781 -7.040 8.163 1.00 19.98 ? 19 GLN A O 1 ATOM 150 C CB . GLN A 1 19 ? 25.784 -6.646 8.060 1.00 23.26 ? 19 GLN A CB 1 ATOM 151 C CG . GLN A 1 19 ? 25.578 -5.947 6.722 1.00 22.62 ? 19 GLN A CG 1 ATOM 152 C CD . GLN A 1 19 ? 24.658 -4.750 6.838 1.00 27.09 ? 19 GLN A CD 1 ATOM 153 O OE1 . GLN A 1 19 ? 23.595 -4.711 6.219 1.00 30.26 ? 19 GLN A OE1 1 ATOM 154 N NE2 . GLN A 1 19 ? 25.050 -3.774 7.654 1.00 27.85 ? 19 GLN A NE2 1 ATOM 155 N N . GLU A 1 20 ? 28.281 -8.187 6.290 1.00 18.48 ? 20 GLU A N 1 ATOM 156 C CA . GLU A 1 20 ? 29.621 -8.049 5.730 1.00 20.80 ? 20 GLU A CA 1 ATOM 157 C C . GLU A 1 20 ? 29.790 -6.762 4.925 1.00 20.24 ? 20 GLU A C 1 ATOM 158 O O . GLU A 1 20 ? 28.857 -6.289 4.276 1.00 21.99 ? 20 GLU A O 1 ATOM 159 C CB . GLU A 1 20 ? 30.006 -9.278 4.905 1.00 21.20 ? 20 GLU A CB 1 ATOM 160 C CG . GLU A 1 20 ? 29.086 -9.582 3.741 1.00 27.31 ? 20 GLU A CG 1 ATOM 161 C CD . GLU A 1 20 ? 29.365 -10.932 3.118 1.00 32.96 ? 20 GLU A CD 1 ATOM 162 O OE1 . GLU A 1 20 ? 30.416 -11.538 3.432 1.00 25.22 ? 20 GLU A OE1 1 ATOM 163 O OE2 . GLU A 1 20 ? 28.526 -11.385 2.308 1.00 41.75 ? 20 GLU A OE2 1 ATOM 164 N N . LEU A 1 21 ? 30.995 -6.208 4.972 1.00 16.77 ? 21 LEU A N 1 ATOM 165 C CA . LEU A 1 21 ? 31.246 -4.890 4.424 1.00 16.06 ? 21 LEU A CA 1 ATOM 166 C C . LEU A 1 21 ? 32.288 -4.943 3.331 1.00 22.85 ? 21 LEU A C 1 ATOM 167 O O . LEU A 1 21 ? 32.023 -4.608 2.176 1.00 26.21 ? 21 LEU A O 1 ATOM 168 C CB . LEU A 1 21 ? 31.740 -3.948 5.529 1.00 14.86 ? 21 LEU A CB 1 ATOM 169 C CG . LEU A 1 21 ? 30.999 -3.910 6.865 1.00 14.50 ? 21 LEU A CG 1 ATOM 170 C CD1 . LEU A 1 21 ? 31.790 -3.099 7.872 1.00 10.63 ? 21 LEU A CD1 1 ATOM 171 C CD2 . LEU A 1 21 ? 29.591 -3.358 6.698 1.00 17.69 ? 21 LEU A CD2 1 ATOM 172 N N . VAL A 1 22 ? 33.481 -5.372 3.715 1.00 24.96 ? 22 VAL A N 1 ATOM 173 C CA . VAL A 1 22 ? 34.649 -5.244 2.872 1.00 22.60 ? 22 VAL A CA 1 ATOM 174 C C . VAL A 1 22 ? 35.581 -6.428 3.088 1.00 21.48 ? 22 VAL A C 1 ATOM 175 O O . VAL A 1 22 ? 35.513 -7.105 4.119 1.00 19.57 ? 22 VAL A O 1 ATOM 176 C CB . VAL A 1 22 ? 35.345 -3.878 3.141 1.00 17.59 ? 22 VAL A CB 1 ATOM 177 C CG1 . VAL A 1 22 ? 36.845 -4.014 3.349 1.00 19.85 ? 22 VAL A CG1 1 ATOM 178 C CG2 . VAL A 1 22 ? 35.029 -2.905 2.031 1.00 15.01 ? 22 VAL A CG2 1 ATOM 179 N N . ARG A 1 23 ? 36.431 -6.683 2.098 1.00 15.49 ? 23 ARG A N 1 ATOM 180 C CA . ARG A 1 23 ? 37.431 -7.723 2.202 1.00 14.19 ? 23 ARG A CA 1 ATOM 181 C C . ARG A 1 23 ? 38.837 -7.146 2.027 1.00 13.57 ? 23 ARG A C 1 ATOM 182 O O . ARG A 1 23 ? 39.217 -6.737 0.924 1.00 13.32 ? 23 ARG A O 1 ATOM 183 C CB . ARG A 1 23 ? 37.149 -8.806 1.165 1.00 12.44 ? 23 ARG A CB 1 ATOM 184 C CG . ARG A 1 23 ? 37.998 -10.031 1.327 1.00 15.31 ? 23 ARG A CG 1 ATOM 185 C CD . ARG A 1 23 ? 37.808 -10.984 0.175 1.00 21.47 ? 23 ARG A CD 1 ATOM 186 N NE . ARG A 1 23 ? 38.711 -12.124 0.297 1.00 22.48 ? 23 ARG A NE 1 ATOM 187 C CZ . ARG A 1 23 ? 38.801 -13.112 -0.584 1.00 22.61 ? 23 ARG A CZ 1 ATOM 188 N NH1 . ARG A 1 23 ? 39.658 -14.100 -0.380 1.00 22.54 ? 23 ARG A NH1 1 ATOM 189 N NH2 . ARG A 1 23 ? 38.040 -13.110 -1.671 1.00 27.27 ? 23 ARG A NH2 1 ATOM 190 N N . ILE A 1 24 ? 39.596 -7.089 3.120 1.00 10.21 ? 24 ILE A N 1 ATOM 191 C CA . ILE A 1 24 ? 41.023 -6.768 3.030 1.00 12.79 ? 24 ILE A CA 1 ATOM 192 C C . ILE A 1 24 ? 41.838 -8.041 3.007 1.00 15.09 ? 24 ILE A C 1 ATOM 193 O O . ILE A 1 24 ? 41.581 -8.959 3.776 1.00 18.76 ? 24 ILE A O 1 ATOM 194 C CB . ILE A 1 24 ? 41.569 -5.865 4.180 1.00 11.08 ? 24 ILE A CB 1 ATOM 195 C CG1 . ILE A 1 24 ? 40.841 -6.118 5.505 1.00 11.88 ? 24 ILE A CG1 1 ATOM 196 C CG2 . ILE A 1 24 ? 41.576 -4.398 3.760 1.00 8.26 ? 24 ILE A CG2 1 ATOM 197 C CD1 . ILE A 1 24 ? 39.592 -5.264 5.736 1.00 19.23 ? 24 ILE A CD1 1 ATOM 198 N N . ARG A 1 25 ? 42.815 -8.086 2.112 1.00 14.68 ? 25 ARG A N 1 ATOM 199 C CA . ARG A 1 25 ? 43.726 -9.210 2.012 1.00 13.69 ? 25 ARG A CA 1 ATOM 200 C C . ARG A 1 25 ? 45.044 -8.721 1.452 1.00 15.52 ? 25 ARG A C 1 ATOM 201 O O . ARG A 1 25 ? 45.114 -7.651 0.852 1.00 16.68 ? 25 ARG A O 1 ATOM 202 C CB . ARG A 1 25 ? 43.145 -10.313 1.123 1.00 11.91 ? 25 ARG A CB 1 ATOM 203 C CG . ARG A 1 25 ? 42.537 -9.824 -0.177 1.00 15.88 ? 25 ARG A CG 1 ATOM 204 C CD . ARG A 1 25 ? 42.186 -10.975 -1.104 1.00 17.79 ? 25 ARG A CD 1 ATOM 205 N NE . ARG A 1 25 ? 43.385 -11.558 -1.695 1.00 20.43 ? 25 ARG A NE 1 ATOM 206 C CZ . ARG A 1 25 ? 43.992 -11.088 -2.779 1.00 21.09 ? 25 ARG A CZ 1 ATOM 207 N NH1 . ARG A 1 25 ? 43.512 -10.022 -3.408 1.00 20.96 ? 25 ARG A NH1 1 ATOM 208 N NH2 . ARG A 1 25 ? 45.085 -11.685 -3.235 1.00 25.26 ? 25 ARG A NH2 1 ATOM 209 N N . SER A 1 26 ? 46.093 -9.501 1.663 1.00 14.95 ? 26 SER A N 1 ATOM 210 C CA . SER A 1 26 ? 47.398 -9.165 1.134 1.00 14.25 ? 26 SER A CA 1 ATOM 211 C C . SER A 1 26 ? 47.652 -9.976 -0.126 1.00 18.96 ? 26 SER A C 1 ATOM 212 O O . SER A 1 26 ? 47.369 -11.171 -0.161 1.00 17.59 ? 26 SER A O 1 ATOM 213 C CB . SER A 1 26 ? 48.463 -9.466 2.172 1.00 12.52 ? 26 SER A CB 1 ATOM 214 O OG . SER A 1 26 ? 49.743 -9.223 1.643 1.00 18.34 ? 26 SER A OG 1 ATOM 215 N N . ASP A 1 27 ? 48.182 -9.330 -1.161 1.00 19.24 ? 27 ASP A N 1 ATOM 216 C CA . ASP A 1 27 ? 48.490 -10.028 -2.406 1.00 16.66 ? 27 ASP A CA 1 ATOM 217 C C . ASP A 1 27 ? 49.636 -11.016 -2.203 1.00 22.47 ? 27 ASP A C 1 ATOM 218 O O . ASP A 1 27 ? 49.885 -11.871 -3.059 1.00 31.03 ? 27 ASP A O 1 ATOM 219 C CB . ASP A 1 27 ? 48.788 -9.049 -3.551 1.00 17.37 ? 27 ASP A CB 1 ATOM 220 C CG . ASP A 1 27 ? 50.010 -8.181 -3.292 1.00 22.45 ? 27 ASP A CG 1 ATOM 221 O OD1 . ASP A 1 27 ? 50.779 -8.470 -2.351 1.00 22.72 ? 27 ASP A OD1 1 ATOM 222 O OD2 . ASP A 1 27 ? 50.204 -7.201 -4.046 1.00 21.11 ? 27 ASP A OD2 1 ATOM 223 N N . ARG A 1 28 ? 50.316 -10.900 -1.061 1.00 18.60 ? 28 ARG A N 1 ATOM 224 C CA . ARG A 1 28 ? 51.372 -11.834 -0.680 1.00 18.39 ? 28 ARG A CA 1 ATOM 225 C C . ARG A 1 28 ? 50.838 -13.236 -0.421 1.00 20.14 ? 28 ARG A C 1 ATOM 226 O O . ARG A 1 28 ? 51.613 -14.152 -0.159 1.00 26.26 ? 28 ARG A O 1 ATOM 227 C CB . ARG A 1 28 ? 52.129 -11.342 0.553 1.00 16.79 ? 28 ARG A CB 1 ATOM 228 C CG . ARG A 1 28 ? 53.157 -10.254 0.282 1.00 22.62 ? 28 ARG A CG 1 ATOM 229 C CD . ARG A 1 28 ? 54.332 -10.361 1.263 1.00 23.07 ? 28 ARG A CD 1 ATOM 230 N NE . ARG A 1 28 ? 55.088 -9.123 1.502 1.00 33.51 ? 28 ARG A NE 1 ATOM 231 C CZ . ARG A 1 28 ? 55.248 -8.105 0.648 1.00 45.20 ? 28 ARG A CZ 1 ATOM 232 N NH1 . ARG A 1 28 ? 54.712 -8.124 -0.572 1.00 37.83 ? 28 ARG A NH1 1 ATOM 233 N NH2 . ARG A 1 28 ? 55.967 -7.050 1.022 1.00 42.46 ? 28 ARG A NH2 1 ATOM 234 N N . ASP A 1 29 ? 49.520 -13.402 -0.507 1.00 19.55 ? 29 ASP A N 1 ATOM 235 C CA . ASP A 1 29 ? 48.883 -14.700 -0.296 1.00 20.12 ? 29 ASP A CA 1 ATOM 236 C C . ASP A 1 29 ? 48.928 -15.609 -1.528 1.00 26.77 ? 29 ASP A C 1 ATOM 237 O O . ASP A 1 29 ? 48.322 -16.686 -1.523 1.00 34.49 ? 29 ASP A O 1 ATOM 238 C CB . ASP A 1 29 ? 47.437 -14.524 0.182 1.00 18.85 ? 29 ASP A CB 1 ATOM 239 C CG . ASP A 1 29 ? 46.548 -13.843 -0.850 1.00 23.26 ? 29 ASP A CG 1 ATOM 240 O OD1 . ASP A 1 29 ? 46.972 -13.662 -2.012 1.00 24.89 ? 29 ASP A OD1 1 ATOM 241 O OD2 . ASP A 1 29 ? 45.412 -13.479 -0.490 1.00 25.76 ? 29 ASP A OD2 1 ATOM 242 N N . LYS A 1 30 ? 49.638 -15.177 -2.574 1.00 24.18 ? 30 LYS A N 1 ATOM 243 C CA . LYS A 1 30 ? 49.834 -15.988 -3.786 1.00 29.97 ? 30 LYS A CA 1 ATOM 244 C C . LYS A 1 30 ? 50.543 -17.316 -3.510 1.00 33.54 ? 30 LYS A C 1 ATOM 245 O O . LYS A 1 30 ? 50.422 -18.263 -4.285 1.00 34.74 ? 30 LYS A O 1 ATOM 246 C CB . LYS A 1 30 ? 50.618 -15.207 -4.845 1.00 34.01 ? 30 LYS A CB 1 ATOM 247 C CG . LYS A 1 30 ? 49.808 -14.137 -5.567 1.00 43.00 ? 30 LYS A CG 1 ATOM 248 N N . ASN A 1 31 ? 51.280 -17.371 -2.403 1.00 32.91 ? 31 ASN A N 1 ATOM 249 C CA . ASN A 1 31 ? 52.058 -18.552 -2.029 1.00 33.05 ? 31 ASN A CA 1 ATOM 250 C C . ASN A 1 31 ? 52.051 -18.796 -0.517 1.00 31.45 ? 31 ASN A C 1 ATOM 251 O O . ASN A 1 31 ? 52.194 -19.937 -0.063 1.00 43.56 ? 31 ASN A O 1 ATOM 252 C CB . ASN A 1 31 ? 53.421 -18.540 -2.729 1.00 39.71 ? 31 ASN A CB 1 ATOM 253 C CG . ASN A 1 31 ? 53.997 -17.140 -2.864 1.00 44.97 ? 31 ASN A CG 1 ATOM 254 O OD1 . ASN A 1 31 ? 54.402 -16.731 -3.958 1.00 42.33 ? 31 ASN A OD1 1 ATOM 255 N ND2 . ASN A 1 31 ? 54.026 -16.392 -1.757 1.00 39.82 ? 31 ASN A ND2 1 ATOM 256 N N . LEU A 1 32 ? 51.901 -17.723 0.256 1.00 25.10 ? 32 LEU A N 1 ATOM 257 C CA . LEU A 1 32 ? 51.726 -17.836 1.703 1.00 24.30 ? 32 LEU A CA 1 ATOM 258 C C . LEU A 1 32 ? 50.300 -18.061 2.184 1.00 26.63 ? 32 LEU A C 1 ATOM 259 O O . LEU A 1 32 ? 49.350 -17.640 1.518 1.00 30.18 ? 32 LEU A O 1 ATOM 260 C CB . LEU A 1 32 ? 52.321 -16.584 2.341 1.00 15.77 ? 32 LEU A CB 1 ATOM 261 C CG . LEU A 1 32 ? 53.796 -16.664 2.747 1.00 21.66 ? 32 LEU A CG 1 ATOM 262 C CD1 . LEU A 1 32 ? 54.660 -17.398 1.720 1.00 31.98 ? 32 LEU A CD1 1 ATOM 263 C CD2 . LEU A 1 32 ? 54.352 -15.274 3.015 1.00 25.11 ? 32 LEU A CD2 1 ATOM 264 N N . SER A 1 33 ? 50.140 -18.743 3.315 1.00 19.08 ? 33 SER A N 1 ATOM 265 C CA . SER A 1 33 ? 48.809 -18.915 3.876 1.00 17.61 ? 33 SER A CA 1 ATOM 266 C C . SER A 1 33 ? 48.627 -17.981 5.063 1.00 22.19 ? 33 SER A C 1 ATOM 267 O O . SER A 1 33 ? 49.172 -18.209 6.143 1.00 23.06 ? 33 SER A O 1 ATOM 268 C CB . SER A 1 33 ? 48.546 -20.363 4.261 1.00 18.65 ? 33 SER A CB 1 ATOM 269 O OG . SER A 1 33 ? 47.158 -20.635 4.207 1.00 19.79 ? 33 SER A OG 1 ATOM 270 N N . LEU A 1 34 ? 47.855 -16.921 4.843 1.00 18.13 ? 34 LEU A N 1 ATOM 271 C CA . LEU A 1 34 ? 47.789 -15.808 5.777 1.00 13.54 ? 34 LEU A CA 1 ATOM 272 C C . LEU A 1 34 ? 46.613 -15.891 6.732 1.00 15.18 ? 34 LEU A C 1 ATOM 273 O O . LEU A 1 34 ? 45.621 -16.570 6.456 1.00 17.55 ? 34 LEU A O 1 ATOM 274 C CB . LEU A 1 34 ? 47.734 -14.491 5.006 1.00 12.25 ? 34 LEU A CB 1 ATOM 275 C CG . LEU A 1 34 ? 48.896 -14.198 4.061 1.00 13.42 ? 34 LEU A CG 1 ATOM 276 C CD1 . LEU A 1 34 ? 48.739 -12.824 3.473 1.00 14.63 ? 34 LEU A CD1 1 ATOM 277 C CD2 . LEU A 1 34 ? 50.216 -14.301 4.788 1.00 17.05 ? 34 LEU A CD2 1 ATOM 278 N N . ARG A 1 35 ? 46.750 -15.193 7.858 1.00 12.59 ? 35 ARG A N 1 ATOM 279 C CA . ARG A 1 35 ? 45.693 -15.047 8.850 1.00 11.24 ? 35 ARG A CA 1 ATOM 280 C C . ARG A 1 35 ? 45.495 -13.577 9.207 1.00 14.60 ? 35 ARG A C 1 ATOM 281 O O . ARG A 1 35 ? 46.456 -12.869 9.518 1.00 18.14 ? 35 ARG A O 1 ATOM 282 C CB . ARG A 1 35 ? 46.017 -15.862 10.097 1.00 11.60 ? 35 ARG A CB 1 ATOM 283 C CG . ARG A 1 35 ? 45.223 -17.147 10.227 1.00 13.64 ? 35 ARG A CG 1 ATOM 284 C CD . ARG A 1 35 ? 45.636 -18.182 9.213 1.00 15.32 ? 35 ARG A CD 1 ATOM 285 N NE . ARG A 1 35 ? 45.125 -19.504 9.553 1.00 20.70 ? 35 ARG A NE 1 ATOM 286 C CZ . ARG A 1 35 ? 45.143 -20.552 8.733 1.00 27.34 ? 35 ARG A CZ 1 ATOM 287 N NH1 . ARG A 1 35 ? 45.632 -20.436 7.502 1.00 22.62 ? 35 ARG A NH1 1 ATOM 288 N NH2 . ARG A 1 35 ? 44.654 -21.719 9.143 1.00 32.00 ? 35 ARG A NH2 1 ATOM 289 N N . TYR A 1 36 ? 44.246 -13.123 9.162 1.00 13.41 ? 36 TYR A N 1 ATOM 290 C CA . TYR A 1 36 ? 43.941 -11.710 9.358 1.00 13.06 ? 36 TYR A CA 1 ATOM 291 C C . TYR A 1 36 ? 43.318 -11.411 10.710 1.00 12.56 ? 36 TYR A C 1 ATOM 292 O O . TYR A 1 36 ? 42.750 -12.286 11.354 1.00 14.62 ? 36 TYR A O 1 ATOM 293 C CB . TYR A 1 36 ? 43.034 -11.209 8.238 1.00 10.56 ? 36 TYR A CB 1 ATOM 294 C CG . TYR A 1 36 ? 43.613 -11.442 6.874 1.00 11.06 ? 36 TYR A CG 1 ATOM 295 C CD1 . TYR A 1 36 ? 44.694 -10.690 6.422 1.00 11.12 ? 36 TYR A CD1 1 ATOM 296 C CD2 . TYR A 1 36 ? 43.094 -12.432 6.037 1.00 12.09 ? 36 TYR A CD2 1 ATOM 297 C CE1 . TYR A 1 36 ? 45.241 -10.911 5.161 1.00 14.02 ? 36 TYR A CE1 1 ATOM 298 C CE2 . TYR A 1 36 ? 43.631 -12.664 4.776 1.00 10.10 ? 36 TYR A CE2 1 ATOM 299 C CZ . TYR A 1 36 ? 44.704 -11.899 4.347 1.00 12.26 ? 36 TYR A CZ 1 ATOM 300 O OH . TYR A 1 36 ? 45.245 -12.114 3.105 1.00 16.43 ? 36 TYR A OH 1 ATOM 301 N N . SER A 1 37 ? 43.431 -10.158 11.128 1.00 10.85 ? 37 SER A N 1 ATOM 302 C CA . SER A 1 37 ? 42.858 -9.705 12.384 1.00 16.12 ? 37 SER A CA 1 ATOM 303 C C . SER A 1 37 ? 42.804 -8.184 12.432 1.00 20.26 ? 37 SER A C 1 ATOM 304 O O . SER A 1 37 ? 43.742 -7.504 11.997 1.00 18.76 ? 37 SER A O 1 ATOM 305 C CB . SER A 1 37 ? 43.675 -10.232 13.561 1.00 19.08 ? 37 SER A CB 1 ATOM 306 O OG . SER A 1 37 ? 45.059 -10.098 13.293 1.00 22.44 ? 37 SER A OG 1 ATOM 307 N N . VAL A 1 38 ? 41.702 -7.654 12.958 1.00 17.18 ? 38 VAL A N 1 ATOM 308 C CA . VAL A 1 38 ? 41.589 -6.220 13.195 1.00 15.92 ? 38 VAL A CA 1 ATOM 309 C C . VAL A 1 38 ? 41.870 -5.882 14.649 1.00 17.09 ? 38 VAL A C 1 ATOM 310 O O . VAL A 1 38 ? 41.652 -6.704 15.536 1.00 20.97 ? 38 VAL A O 1 ATOM 311 C CB . VAL A 1 38 ? 40.206 -5.666 12.818 1.00 12.51 ? 38 VAL A CB 1 ATOM 312 C CG1 . VAL A 1 38 ? 40.199 -5.256 11.381 1.00 17.70 ? 38 VAL A CG1 1 ATOM 313 C CG2 . VAL A 1 38 ? 39.111 -6.670 13.104 1.00 12.01 ? 38 VAL A CG2 1 ATOM 314 N N . THR A 1 39 ? 42.355 -4.669 14.883 1.00 15.38 ? 39 THR A N 1 ATOM 315 C CA . THR A 1 39 ? 42.536 -4.157 16.234 1.00 15.27 ? 39 THR A CA 1 ATOM 316 C C . THR A 1 39 ? 41.914 -2.771 16.354 1.00 18.13 ? 39 THR A C 1 ATOM 317 O O . THR A 1 39 ? 41.559 -2.157 15.345 1.00 20.39 ? 39 THR A O 1 ATOM 318 C CB . THR A 1 39 ? 44.020 -4.068 16.602 1.00 18.80 ? 39 THR A CB 1 ATOM 319 O OG1 . THR A 1 39 ? 44.762 -3.546 15.489 1.00 21.69 ? 39 THR A OG1 1 ATOM 320 C CG2 . THR A 1 39 ? 44.554 -5.434 16.978 1.00 16.15 ? 39 THR A CG2 1 ATOM 321 N N . GLY A 1 40 ? 41.786 -2.286 17.589 1.00 19.38 ? 40 GLY A N 1 ATOM 322 C CA . GLY A 1 40 ? 41.259 -0.948 17.854 1.00 19.29 ? 40 GLY A CA 1 ATOM 323 C C . GLY A 1 40 ? 39.880 -0.924 18.496 1.00 17.71 ? 40 GLY A C 1 ATOM 324 O O . GLY A 1 40 ? 39.219 -1.961 18.594 1.00 17.12 ? 40 GLY A O 1 ATOM 325 N N . PRO A 1 41 ? 39.440 0.268 18.944 1.00 16.08 ? 41 PRO A N 1 ATOM 326 C CA . PRO A 1 41 ? 38.113 0.479 19.517 1.00 15.06 ? 41 PRO A CA 1 ATOM 327 C C . PRO A 1 41 ? 37.021 0.086 18.532 1.00 15.68 ? 41 PRO A C 1 ATOM 328 O O . PRO A 1 41 ? 36.987 0.595 17.412 1.00 17.47 ? 41 PRO A O 1 ATOM 329 C CB . PRO A 1 41 ? 38.080 1.986 19.760 1.00 12.97 ? 41 PRO A CB 1 ATOM 330 C CG . PRO A 1 41 ? 39.491 2.371 19.897 1.00 12.41 ? 41 PRO A CG 1 ATOM 331 C CD . PRO A 1 41 ? 40.221 1.515 18.931 1.00 12.47 ? 41 PRO A CD 1 ATOM 332 N N . GLY A 1 42 ? 36.141 -0.818 18.947 1.00 12.90 ? 42 GLY A N 1 ATOM 333 C CA . GLY A 1 42 ? 35.137 -1.365 18.042 1.00 13.89 ? 42 GLY A CA 1 ATOM 334 C C . GLY A 1 42 ? 35.512 -2.762 17.598 1.00 16.62 ? 42 GLY A C 1 ATOM 335 O O . GLY A 1 42 ? 34.653 -3.556 17.199 1.00 15.56 ? 42 GLY A O 1 ATOM 336 N N . ALA A 1 43 ? 36.796 -3.087 17.728 1.00 17.16 ? 43 ALA A N 1 ATOM 337 C CA . ALA A 1 43 ? 37.304 -4.403 17.348 1.00 15.62 ? 43 ALA A CA 1 ATOM 338 C C . ALA A 1 43 ? 37.747 -5.268 18.534 1.00 15.07 ? 43 ALA A C 1 ATOM 339 O O . ALA A 1 43 ? 37.100 -6.263 18.859 1.00 25.56 ? 43 ALA A O 1 ATOM 340 C CB . ALA A 1 43 ? 38.440 -4.260 16.342 1.00 17.22 ? 43 ALA A CB 1 ATOM 341 N N . ASP A 1 44 ? 38.856 -4.893 19.168 1.00 11.74 ? 44 ASP A N 1 ATOM 342 C CA . ASP A 1 44 ? 39.467 -5.711 20.196 1.00 14.73 ? 44 ASP A CA 1 ATOM 343 C C . ASP A 1 44 ? 39.446 -4.840 21.437 1.00 20.75 ? 44 ASP A C 1 ATOM 344 O O . ASP A 1 44 ? 39.456 -5.357 22.547 1.00 27.70 ? 44 ASP A O 1 ATOM 345 C CB . ASP A 1 44 ? 40.868 -6.277 19.928 1.00 21.14 ? 44 ASP A CB 1 ATOM 346 C CG . ASP A 1 44 ? 41.972 -5.254 20.122 1.00 26.36 ? 44 ASP A CG 1 ATOM 347 O OD1 . ASP A 1 44 ? 41.915 -4.162 19.511 1.00 23.73 ? 44 ASP A OD1 1 ATOM 348 O OD2 . ASP A 1 44 ? 42.914 -5.561 20.884 1.00 29.67 ? 44 ASP A OD2 1 ATOM 349 N N . GLN A 1 45 ? 39.422 -3.522 21.238 1.00 22.21 ? 45 GLN A N 1 ATOM 350 C CA . GLN A 1 45 ? 39.261 -2.551 22.325 1.00 18.51 ? 45 GLN A CA 1 ATOM 351 C C . GLN A 1 45 ? 37.803 -2.086 22.403 1.00 20.08 ? 45 GLN A C 1 ATOM 352 O O . GLN A 1 45 ? 37.076 -2.169 21.409 1.00 20.57 ? 45 GLN A O 1 ATOM 353 C CB . GLN A 1 45 ? 40.186 -1.352 22.119 1.00 17.58 ? 45 GLN A CB 1 ATOM 354 C CG . GLN A 1 45 ? 41.661 -1.686 22.185 1.00 20.27 ? 45 GLN A CG 1 ATOM 355 C CD . GLN A 1 45 ? 42.543 -0.450 22.188 1.00 27.95 ? 45 GLN A CD 1 ATOM 356 O OE1 . GLN A 1 45 ? 43.076 -0.069 23.230 1.00 39.31 ? 45 GLN A OE1 1 ATOM 357 N NE2 . GLN A 1 45 ? 42.701 0.184 21.024 1.00 21.97 ? 45 GLN A NE2 1 ATOM 358 N N . PRO A 1 46 ? 37.368 -1.580 23.578 1.00 22.60 ? 46 PRO A N 1 ATOM 359 C CA . PRO A 1 46 ? 35.954 -1.227 23.737 1.00 21.10 ? 46 PRO A CA 1 ATOM 360 C C . PRO A 1 46 ? 35.518 -0.110 22.787 1.00 21.03 ? 46 PRO A C 1 ATOM 361 O O . PRO A 1 46 ? 36.303 0.803 22.518 1.00 19.03 ? 46 PRO A O 1 ATOM 362 C CB . PRO A 1 46 ? 35.866 -0.764 25.196 1.00 20.13 ? 46 PRO A CB 1 ATOM 363 C CG . PRO A 1 46 ? 37.063 -1.342 25.855 1.00 22.21 ? 46 PRO A CG 1 ATOM 364 C CD . PRO A 1 46 ? 38.127 -1.304 24.809 1.00 20.96 ? 46 PRO A CD 1 ATOM 365 N N . PRO A 1 47 ? 34.281 -0.200 22.258 1.00 20.89 ? 47 PRO A N 1 ATOM 366 C CA . PRO A 1 47 ? 33.360 -1.304 22.518 1.00 20.64 ? 47 PRO A CA 1 ATOM 367 C C . PRO A 1 47 ? 33.697 -2.528 21.668 1.00 21.09 ? 47 PRO A C 1 ATOM 368 O O . PRO A 1 47 ? 33.838 -2.429 20.449 1.00 19.12 ? 47 PRO A O 1 ATOM 369 C CB . PRO A 1 47 ? 31.997 -0.726 22.138 1.00 18.71 ? 47 PRO A CB 1 ATOM 370 C CG . PRO A 1 47 ? 32.292 0.315 21.121 1.00 18.31 ? 47 PRO A CG 1 ATOM 371 C CD . PRO A 1 47 ? 33.704 0.800 21.341 1.00 18.16 ? 47 PRO A CD 1 ATOM 372 N N . THR A 1 48 ? 33.818 -3.669 22.337 1.00 21.93 ? 48 THR A N 1 ATOM 373 C CA . THR A 1 48 ? 34.292 -4.916 21.742 1.00 19.31 ? 48 THR A CA 1 ATOM 374 C C . THR A 1 48 ? 33.289 -5.575 20.808 1.00 18.04 ? 48 THR A C 1 ATOM 375 O O . THR A 1 48 ? 32.092 -5.616 21.099 1.00 17.98 ? 48 THR A O 1 ATOM 376 C CB . THR A 1 48 ? 34.665 -5.912 22.867 1.00 26.47 ? 48 THR A CB 1 ATOM 377 O OG1 . THR A 1 48 ? 35.893 -5.493 23.475 1.00 28.84 ? 48 THR A OG1 1 ATOM 378 C CG2 . THR A 1 48 ? 34.806 -7.356 22.343 1.00 33.88 ? 48 THR A CG2 1 ATOM 379 N N . GLY A 1 49 ? 33.798 -6.084 19.687 1.00 15.31 ? 49 GLY A N 1 ATOM 380 C CA . GLY A 1 49 ? 33.054 -7.024 18.845 1.00 20.61 ? 49 GLY A CA 1 ATOM 381 C C . GLY A 1 49 ? 32.137 -6.436 17.788 1.00 18.51 ? 49 GLY A C 1 ATOM 382 O O . GLY A 1 49 ? 31.409 -7.166 17.115 1.00 18.67 ? 49 GLY A O 1 ATOM 383 N N . ILE A 1 50 ? 32.171 -5.117 17.640 1.00 17.97 ? 50 ILE A N 1 ATOM 384 C CA . ILE A 1 50 ? 31.352 -4.437 16.643 1.00 17.60 ? 50 ILE A CA 1 ATOM 385 C C . ILE A 1 50 ? 31.817 -4.835 15.245 1.00 17.92 ? 50 ILE A C 1 ATOM 386 O O . ILE A 1 50 ? 31.002 -5.122 14.362 1.00 18.65 ? 50 ILE A O 1 ATOM 387 C CB . ILE A 1 50 ? 31.413 -2.892 16.797 1.00 16.43 ? 50 ILE A CB 1 ATOM 388 C CG1 . ILE A 1 50 ? 31.375 -2.471 18.273 1.00 16.38 ? 50 ILE A CG1 1 ATOM 389 C CG2 . ILE A 1 50 ? 30.292 -2.232 16.010 1.00 15.78 ? 50 ILE A CG2 1 ATOM 390 C CD1 . ILE A 1 50 ? 30.077 -2.823 19.015 1.00 20.61 ? 50 ILE A CD1 1 ATOM 391 N N . PHE A 1 51 ? 33.134 -4.870 15.068 1.00 14.94 ? 51 PHE A N 1 ATOM 392 C CA . PHE A 1 51 ? 33.728 -5.220 13.793 1.00 12.80 ? 51 PHE A CA 1 ATOM 393 C C . PHE A 1 51 ? 34.612 -6.446 13.928 1.00 15.06 ? 51 PHE A C 1 ATOM 394 O O . PHE A 1 51 ? 35.467 -6.512 14.812 1.00 24.07 ? 51 PHE A O 1 ATOM 395 C CB . PHE A 1 51 ? 34.520 -4.040 13.251 1.00 12.98 ? 51 PHE A CB 1 ATOM 396 C CG . PHE A 1 51 ? 33.675 -2.839 12.950 1.00 15.37 ? 51 PHE A CG 1 ATOM 397 C CD1 . PHE A 1 51 ? 33.146 -2.647 11.684 1.00 17.21 ? 51 PHE A CD1 1 ATOM 398 C CD2 . PHE A 1 51 ? 33.397 -1.904 13.935 1.00 16.61 ? 51 PHE A CD2 1 ATOM 399 C CE1 . PHE A 1 51 ? 32.363 -1.539 11.404 1.00 15.53 ? 51 PHE A CE1 1 ATOM 400 C CE2 . PHE A 1 51 ? 32.611 -0.795 13.659 1.00 15.37 ? 51 PHE A CE2 1 ATOM 401 C CZ . PHE A 1 51 ? 32.094 -0.615 12.393 1.00 14.34 ? 51 PHE A CZ 1 ATOM 402 N N . ILE A 1 52 ? 34.386 -7.422 13.056 1.00 12.23 ? 52 ILE A N 1 ATOM 403 C CA . ILE A 1 52 ? 35.113 -8.686 13.094 1.00 11.59 ? 52 ILE A CA 1 ATOM 404 C C . ILE A 1 52 ? 35.692 -8.966 11.725 1.00 13.64 ? 52 ILE A C 1 ATOM 405 O O . ILE A 1 52 ? 35.181 -8.473 10.720 1.00 14.94 ? 52 ILE A O 1 ATOM 406 C CB . ILE A 1 52 ? 34.202 -9.862 13.499 1.00 10.64 ? 52 ILE A CB 1 ATOM 407 C CG1 . ILE A 1 52 ? 32.963 -9.923 12.593 1.00 11.87 ? 52 ILE A CG1 1 ATOM 408 C CG2 . ILE A 1 52 ? 33.812 -9.749 14.963 1.00 11.86 ? 52 ILE A CG2 1 ATOM 409 C CD1 . ILE A 1 52 ? 32.208 -11.235 12.630 1.00 18.22 ? 52 ILE A CD1 1 ATOM 410 N N . ILE A 1 53 ? 36.755 -9.759 11.679 1.00 14.06 ? 53 ILE A N 1 ATOM 411 C CA . ILE A 1 53 ? 37.365 -10.110 10.406 1.00 11.76 ? 53 ILE A CA 1 ATOM 412 C C . ILE A 1 53 ? 37.569 -11.614 10.297 1.00 12.47 ? 53 ILE A C 1 ATOM 413 O O . ILE A 1 53 ? 38.170 -12.232 11.178 1.00 15.94 ? 53 ILE A O 1 ATOM 414 C CB . ILE A 1 53 ? 38.684 -9.328 10.158 1.00 13.06 ? 53 ILE A CB 1 ATOM 415 C CG1 . ILE A 1 53 ? 39.095 -9.417 8.686 1.00 12.27 ? 53 ILE A CG1 1 ATOM 416 C CG2 . ILE A 1 53 ? 39.798 -9.800 11.084 1.00 12.57 ? 53 ILE A CG2 1 ATOM 417 C CD1 . ILE A 1 53 ? 40.169 -8.424 8.291 1.00 11.69 ? 53 ILE A CD1 1 ATOM 418 N N . ASN A 1 54 ? 37.036 -12.201 9.227 1.00 14.43 ? 54 ASN A N 1 ATOM 419 C CA . ASN A 1 54 ? 37.256 -13.612 8.949 1.00 12.55 ? 54 ASN A CA 1 ATOM 420 C C . ASN A 1 54 ? 38.742 -13.832 8.741 1.00 12.52 ? 54 ASN A C 1 ATOM 421 O O . ASN A 1 54 ? 39.326 -13.252 7.825 1.00 12.03 ? 54 ASN A O 1 ATOM 422 C CB . ASN A 1 54 ? 36.476 -14.063 7.718 1.00 12.12 ? 54 ASN A CB 1 ATOM 423 C CG . ASN A 1 54 ? 36.679 -15.535 7.409 1.00 13.54 ? 54 ASN A CG 1 ATOM 424 O OD1 . ASN A 1 54 ? 37.796 -15.984 7.134 1.00 14.69 ? 54 ASN A OD1 1 ATOM 425 N ND2 . ASN A 1 54 ? 35.595 -16.295 7.447 1.00 16.78 ? 54 ASN A ND2 1 ATOM 426 N N . PRO A 1 55 ? 39.355 -14.686 9.582 1.00 13.63 ? 55 PRO A N 1 ATOM 427 C CA . PRO A 1 55 ? 40.811 -14.787 9.643 1.00 12.09 ? 55 PRO A CA 1 ATOM 428 C C . PRO A 1 55 ? 41.398 -15.322 8.347 1.00 13.56 ? 55 PRO A C 1 ATOM 429 O O . PRO A 1 55 ? 42.564 -15.067 8.056 1.00 15.03 ? 55 PRO A O 1 ATOM 430 C CB . PRO A 1 55 ? 41.047 -15.779 10.783 1.00 8.85 ? 55 PRO A CB 1 ATOM 431 C CG . PRO A 1 55 ? 39.807 -16.581 10.842 1.00 10.25 ? 55 PRO A CG 1 ATOM 432 C CD . PRO A 1 55 ? 38.701 -15.640 10.495 1.00 9.90 ? 55 PRO A CD 1 ATOM 433 N N . ILE A 1 56 ? 40.583 -16.040 7.577 1.00 10.58 ? 56 ILE A N 1 ATOM 434 C CA . ILE A 1 56 ? 41.042 -16.700 6.368 1.00 10.35 ? 56 ILE A CA 1 ATOM 435 C C . ILE A 1 56 ? 40.813 -15.818 5.154 1.00 13.57 ? 56 ILE A C 1 ATOM 436 O O . ILE A 1 56 ? 41.760 -15.508 4.428 1.00 18.84 ? 56 ILE A O 1 ATOM 437 C CB . ILE A 1 56 ? 40.340 -18.073 6.163 1.00 12.51 ? 56 ILE A CB 1 ATOM 438 C CG1 . ILE A 1 56 ? 40.604 -19.017 7.349 1.00 14.69 ? 56 ILE A CG1 1 ATOM 439 C CG2 . ILE A 1 56 ? 40.742 -18.714 4.824 1.00 11.78 ? 56 ILE A CG2 1 ATOM 440 C CD1 . ILE A 1 56 ? 42.085 -19.218 7.727 1.00 16.14 ? 56 ILE A CD1 1 ATOM 441 N N . SER A 1 57 ? 39.558 -15.417 4.944 1.00 14.31 ? 57 SER A N 1 ATOM 442 C CA . SER A 1 57 ? 39.153 -14.680 3.746 1.00 13.77 ? 57 SER A CA 1 ATOM 443 C C . SER A 1 57 ? 39.543 -13.215 3.815 1.00 14.24 ? 57 SER A C 1 ATOM 444 O O . SER A 1 57 ? 39.774 -12.585 2.782 1.00 16.77 ? 57 SER A O 1 ATOM 445 C CB . SER A 1 57 ? 37.644 -14.794 3.533 1.00 14.49 ? 57 SER A CB 1 ATOM 446 O OG . SER A 1 57 ? 36.928 -14.185 4.594 1.00 13.25 ? 57 SER A OG 1 ATOM 447 N N . GLY A 1 58 ? 39.610 -12.681 5.034 1.00 11.46 ? 58 GLY A N 1 ATOM 448 C CA . GLY A 1 58 ? 39.927 -11.277 5.259 1.00 10.01 ? 58 GLY A CA 1 ATOM 449 C C . GLY A 1 58 ? 38.702 -10.395 5.153 1.00 12.37 ? 58 GLY A C 1 ATOM 450 O O . GLY A 1 58 ? 38.819 -9.177 5.060 1.00 14.17 ? 58 GLY A O 1 ATOM 451 N N . GLN A 1 59 ? 37.529 -11.022 5.162 1.00 11.69 ? 59 GLN A N 1 ATOM 452 C CA . GLN A 1 59 ? 36.251 -10.324 5.104 1.00 11.20 ? 59 GLN A CA 1 ATOM 453 C C . GLN A 1 59 ? 35.935 -9.618 6.426 1.00 13.80 ? 59 GLN A C 1 ATOM 454 O O . GLN A 1 59 ? 36.009 -10.219 7.501 1.00 12.48 ? 59 GLN A O 1 ATOM 455 C CB . GLN A 1 59 ? 35.145 -11.320 4.772 1.00 11.43 ? 59 GLN A CB 1 ATOM 456 C CG . GLN A 1 59 ? 33.765 -10.722 4.653 1.00 14.50 ? 59 GLN A CG 1 ATOM 457 C CD . GLN A 1 59 ? 33.474 -10.210 3.264 1.00 16.46 ? 59 GLN A CD 1 ATOM 458 O OE1 . GLN A 1 59 ? 33.694 -10.906 2.270 1.00 14.83 ? 59 GLN A OE1 1 ATOM 459 N NE2 . GLN A 1 59 ? 32.968 -8.985 3.184 1.00 21.09 ? 59 GLN A NE2 1 ATOM 460 N N . LEU A 1 60 ? 35.571 -8.342 6.333 1.00 15.24 ? 60 LEU A N 1 ATOM 461 C CA . LEU A 1 60 ? 35.200 -7.541 7.495 1.00 13.39 ? 60 LEU A CA 1 ATOM 462 C C . LEU A 1 60 ? 33.677 -7.474 7.634 1.00 15.82 ? 60 LEU A C 1 ATOM 463 O O . LEU A 1 60 ? 32.955 -7.464 6.629 1.00 16.76 ? 60 LEU A O 1 ATOM 464 C CB . LEU A 1 60 ? 35.758 -6.136 7.336 1.00 13.57 ? 60 LEU A CB 1 ATOM 465 C CG . LEU A 1 60 ? 36.095 -5.376 8.607 1.00 12.83 ? 60 LEU A CG 1 ATOM 466 C CD1 . LEU A 1 60 ? 37.556 -5.573 8.917 1.00 14.39 ? 60 LEU A CD1 1 ATOM 467 C CD2 . LEU A 1 60 ? 35.808 -3.909 8.402 1.00 13.08 ? 60 LEU A CD2 1 ATOM 468 N N . SER A 1 61 ? 33.189 -7.418 8.874 1.00 12.67 ? 61 SER A N 1 ATOM 469 C CA . SER A 1 61 ? 31.744 -7.426 9.134 1.00 13.15 ? 61 SER A CA 1 ATOM 470 C C . SER A 1 61 ? 31.327 -6.640 10.388 1.00 14.89 ? 61 SER A C 1 ATOM 471 O O . SER A 1 61 ? 32.081 -6.569 11.360 1.00 15.92 ? 61 SER A O 1 ATOM 472 C CB . SER A 1 61 ? 31.243 -8.867 9.241 1.00 14.68 ? 61 SER A CB 1 ATOM 473 O OG . SER A 1 61 ? 31.718 -9.669 8.169 1.00 12.47 ? 61 SER A OG 1 ATOM 474 N N . VAL A 1 62 ? 30.133 -6.044 10.350 1.00 14.04 ? 62 VAL A N 1 ATOM 475 C CA . VAL A 1 62 ? 29.499 -5.474 11.545 1.00 12.87 ? 62 VAL A CA 1 ATOM 476 C C . VAL A 1 62 ? 28.541 -6.478 12.157 1.00 15.84 ? 62 VAL A C 1 ATOM 477 O O . VAL A 1 62 ? 27.898 -7.242 11.437 1.00 19.06 ? 62 VAL A O 1 ATOM 478 C CB . VAL A 1 62 ? 28.685 -4.216 11.248 1.00 13.21 ? 62 VAL A CB 1 ATOM 479 C CG1 . VAL A 1 62 ? 29.541 -3.000 11.363 1.00 13.71 ? 62 VAL A CG1 1 ATOM 480 C CG2 . VAL A 1 62 ? 28.021 -4.306 9.886 1.00 17.89 ? 62 VAL A CG2 1 ATOM 481 N N . THR A 1 63 ? 28.421 -6.451 13.479 1.00 12.69 ? 63 THR A N 1 ATOM 482 C CA . THR A 1 63 ? 27.655 -7.469 14.187 1.00 15.00 ? 63 THR A CA 1 ATOM 483 C C . THR A 1 63 ? 26.345 -6.960 14.785 1.00 20.07 ? 63 THR A C 1 ATOM 484 O O . THR A 1 63 ? 25.427 -7.744 15.029 1.00 21.85 ? 63 THR A O 1 ATOM 485 C CB . THR A 1 63 ? 28.497 -8.112 15.292 1.00 17.95 ? 63 THR A CB 1 ATOM 486 O OG1 . THR A 1 63 ? 28.784 -7.140 16.303 1.00 15.86 ? 63 THR A OG1 1 ATOM 487 C CG2 . THR A 1 63 ? 29.808 -8.637 14.718 1.00 20.86 ? 63 THR A CG2 1 ATOM 488 N N . LYS A 1 64 ? 26.278 -5.653 15.036 1.00 22.58 ? 64 LYS A N 1 ATOM 489 C CA . LYS A 1 64 ? 25.063 -4.988 15.518 1.00 20.44 ? 64 LYS A CA 1 ATOM 490 C C . LYS A 1 64 ? 24.849 -3.663 14.759 1.00 21.59 ? 64 LYS A C 1 ATOM 491 O O . LYS A 1 64 ? 25.728 -3.240 14.001 1.00 23.25 ? 64 LYS A O 1 ATOM 492 C CB . LYS A 1 64 ? 25.133 -4.766 17.037 1.00 15.71 ? 64 LYS A CB 1 ATOM 493 C CG . LYS A 1 64 ? 26.105 -3.679 17.486 1.00 17.97 ? 64 LYS A CG 1 ATOM 494 C CD . LYS A 1 64 ? 25.740 -3.099 18.864 1.00 21.72 ? 64 LYS A CD 1 ATOM 495 C CE . LYS A 1 64 ? 26.184 -4.014 20.008 1.00 32.48 ? 64 LYS A CE 1 ATOM 496 N NZ . LYS A 1 64 ? 25.690 -3.564 21.340 1.00 25.12 ? 64 LYS A NZ 1 ATOM 497 N N . PRO A 1 65 ? 23.680 -3.009 14.928 1.00 21.34 ? 65 PRO A N 1 ATOM 498 C CA . PRO A 1 65 ? 23.554 -1.725 14.247 1.00 20.61 ? 65 PRO A CA 1 ATOM 499 C C . PRO A 1 65 ? 24.402 -0.651 14.921 1.00 18.93 ? 65 PRO A C 1 ATOM 500 O O . PRO A 1 65 ? 24.704 -0.750 16.110 1.00 16.70 ? 65 PRO A O 1 ATOM 501 C CB . PRO A 1 65 ? 22.060 -1.393 14.378 1.00 22.83 ? 65 PRO A CB 1 ATOM 502 C CG . PRO A 1 65 ? 21.402 -2.626 14.898 1.00 21.46 ? 65 PRO A CG 1 ATOM 503 C CD . PRO A 1 65 ? 22.454 -3.344 15.672 1.00 24.23 ? 65 PRO A CD 1 ATOM 504 N N . LEU A 1 66 ? 24.790 0.361 14.157 1.00 21.50 ? 66 LEU A N 1 ATOM 505 C CA . LEU A 1 66 ? 25.612 1.439 14.688 1.00 22.21 ? 66 LEU A CA 1 ATOM 506 C C . LEU A 1 66 ? 24.746 2.616 15.141 1.00 21.61 ? 66 LEU A C 1 ATOM 507 O O . LEU A 1 66 ? 23.545 2.657 14.854 1.00 20.52 ? 66 LEU A O 1 ATOM 508 C CB . LEU A 1 66 ? 26.653 1.885 13.653 1.00 19.89 ? 66 LEU A CB 1 ATOM 509 C CG . LEU A 1 66 ? 27.596 0.839 13.044 1.00 11.58 ? 66 LEU A CG 1 ATOM 510 C CD1 . LEU A 1 66 ? 28.543 1.488 12.061 1.00 11.32 ? 66 LEU A CD1 1 ATOM 511 C CD2 . LEU A 1 66 ? 28.381 0.112 14.104 1.00 12.37 ? 66 LEU A CD2 1 ATOM 512 N N . ASP A 1 67 ? 25.362 3.548 15.871 1.00 18.69 ? 67 ASP A N 1 ATOM 513 C CA . ASP A 1 67 ? 24.700 4.764 16.348 1.00 17.80 ? 67 ASP A CA 1 ATOM 514 C C . ASP A 1 67 ? 25.676 5.928 16.255 1.00 20.78 ? 67 ASP A C 1 ATOM 515 O O . ASP A 1 67 ? 26.660 5.986 17.005 1.00 18.24 ? 67 ASP A O 1 ATOM 516 C CB . ASP A 1 67 ? 24.208 4.594 17.791 1.00 18.55 ? 67 ASP A CB 1 ATOM 517 C CG . ASP A 1 67 ? 23.636 5.881 18.385 1.00 24.57 ? 67 ASP A CG 1 ATOM 518 O OD1 . ASP A 1 67 ? 23.292 6.817 17.624 1.00 26.23 ? 67 ASP A OD1 1 ATOM 519 O OD2 . ASP A 1 67 ? 23.516 5.949 19.628 1.00 24.06 ? 67 ASP A OD2 1 ATOM 520 N N . ARG A 1 68 ? 25.386 6.851 15.338 1.00 16.83 ? 68 ARG A N 1 ATOM 521 C CA . ARG A 1 68 ? 26.256 7.987 15.064 1.00 14.23 ? 68 ARG A CA 1 ATOM 522 C C . ARG A 1 68 ? 26.387 8.911 16.277 1.00 18.73 ? 68 ARG A C 1 ATOM 523 O O . ARG A 1 68 ? 27.443 9.504 16.512 1.00 19.32 ? 68 ARG A O 1 ATOM 524 C CB . ARG A 1 68 ? 25.737 8.772 13.859 1.00 15.71 ? 68 ARG A CB 1 ATOM 525 C CG . ARG A 1 68 ? 26.733 9.795 13.311 1.00 17.56 ? 68 ARG A CG 1 ATOM 526 C CD . ARG A 1 68 ? 26.035 10.984 12.665 1.00 16.92 ? 68 ARG A CD 1 ATOM 527 N NE . ARG A 1 68 ? 25.222 11.714 13.633 1.00 20.05 ? 68 ARG A NE 1 ATOM 528 C CZ . ARG A 1 68 ? 25.666 12.720 14.384 1.00 21.61 ? 68 ARG A CZ 1 ATOM 529 N NH1 . ARG A 1 68 ? 26.921 13.145 14.277 1.00 20.34 ? 68 ARG A NH1 1 ATOM 530 N NH2 . ARG A 1 68 ? 24.848 13.306 15.248 1.00 25.00 ? 68 ARG A NH2 1 ATOM 531 N N . GLU A 1 69 ? 25.310 9.020 17.047 1.00 20.19 ? 69 GLU A N 1 ATOM 532 C CA . GLU A 1 69 ? 25.282 9.895 18.211 1.00 18.22 ? 69 GLU A CA 1 ATOM 533 C C . GLU A 1 69 ? 26.107 9.322 19.361 1.00 18.30 ? 69 GLU A C 1 ATOM 534 O O . GLU A 1 69 ? 26.454 10.038 20.304 1.00 18.56 ? 69 GLU A O 1 ATOM 535 C CB . GLU A 1 69 ? 23.836 10.161 18.643 1.00 19.72 ? 69 GLU A CB 1 ATOM 536 C CG . GLU A 1 69 ? 23.070 11.109 17.714 1.00 19.79 ? 69 GLU A CG 1 ATOM 537 C CD . GLU A 1 69 ? 22.749 10.503 16.346 1.00 18.47 ? 69 GLU A CD 1 ATOM 538 O OE1 . GLU A 1 69 ? 22.171 9.392 16.283 1.00 17.15 ? 69 GLU A OE1 1 ATOM 539 O OE2 . GLU A 1 69 ? 23.054 11.150 15.323 1.00 16.32 ? 69 GLU A OE2 1 ATOM 540 N N . LEU A 1 70 ? 26.421 8.031 19.265 1.00 17.31 ? 70 LEU A N 1 ATOM 541 C CA . LEU A 1 70 ? 27.249 7.345 20.255 1.00 17.22 ? 70 LEU A CA 1 ATOM 542 C C . LEU A 1 70 ? 28.723 7.360 19.845 1.00 17.10 ? 70 LEU A C 1 ATOM 543 O O . LEU A 1 70 ? 29.581 7.791 20.618 1.00 15.72 ? 70 LEU A O 1 ATOM 544 C CB . LEU A 1 70 ? 26.761 5.911 20.442 1.00 18.53 ? 70 LEU A CB 1 ATOM 545 C CG . LEU A 1 70 ? 27.243 5.140 21.669 1.00 17.46 ? 70 LEU A CG 1 ATOM 546 C CD1 . LEU A 1 70 ? 26.518 5.589 22.939 1.00 14.49 ? 70 LEU A CD1 1 ATOM 547 C CD2 . LEU A 1 70 ? 27.036 3.648 21.424 1.00 25.44 ? 70 LEU A CD2 1 ATOM 548 N N . ILE A 1 71 ? 29.006 6.873 18.637 1.00 17.06 ? 71 ILE A N 1 ATOM 549 C CA . ILE A 1 71 ? 30.335 6.966 18.028 1.00 18.55 ? 71 ILE A CA 1 ATOM 550 C C . ILE A 1 71 ? 30.126 7.243 16.551 1.00 16.51 ? 71 ILE A C 1 ATOM 551 O O . ILE A 1 71 ? 29.290 6.610 15.913 1.00 15.38 ? 71 ILE A O 1 ATOM 552 C CB . ILE A 1 71 ? 31.178 5.669 18.191 1.00 17.90 ? 71 ILE A CB 1 ATOM 553 C CG1 . ILE A 1 71 ? 31.380 5.315 19.667 1.00 16.02 ? 71 ILE A CG1 1 ATOM 554 C CG2 . ILE A 1 71 ? 32.549 5.827 17.525 1.00 15.96 ? 71 ILE A CG2 1 ATOM 555 C CD1 . ILE A 1 71 ? 31.393 3.824 19.945 1.00 16.75 ? 71 ILE A CD1 1 ATOM 556 N N . ALA A 1 72 ? 30.899 8.190 16.024 1.00 15.35 ? 72 ALA A N 1 ATOM 557 C CA . ALA A 1 72 ? 30.726 8.698 14.673 1.00 10.76 ? 72 ALA A CA 1 ATOM 558 C C . ALA A 1 72 ? 31.709 8.083 13.702 1.00 12.56 ? 72 ALA A C 1 ATOM 559 O O . ALA A 1 72 ? 31.407 7.925 12.526 1.00 19.59 ? 72 ALA A O 1 ATOM 560 C CB . ALA A 1 72 ? 30.875 10.193 14.667 1.00 15.45 ? 72 ALA A CB 1 ATOM 561 N N . ARG A 1 73 ? 32.892 7.744 14.188 1.00 12.62 ? 73 ARG A N 1 ATOM 562 C CA . ARG A 1 73 ? 33.938 7.235 13.323 1.00 13.18 ? 73 ARG A CA 1 ATOM 563 C C . ARG A 1 73 ? 34.788 6.237 14.092 1.00 16.51 ? 73 ARG A C 1 ATOM 564 O O . ARG A 1 73 ? 35.222 6.511 15.217 1.00 17.25 ? 73 ARG A O 1 ATOM 565 C CB . ARG A 1 73 ? 34.777 8.398 12.763 1.00 14.77 ? 73 ARG A CB 1 ATOM 566 C CG . ARG A 1 73 ? 36.217 8.056 12.406 1.00 18.11 ? 73 ARG A CG 1 ATOM 567 C CD . ARG A 1 73 ? 37.013 9.287 12.002 1.00 19.88 ? 73 ARG A CD 1 ATOM 568 N NE . ARG A 1 73 ? 36.888 9.575 10.577 1.00 25.70 ? 73 ARG A NE 1 ATOM 569 C CZ . ARG A 1 73 ? 36.244 10.624 10.066 1.00 37.78 ? 73 ARG A CZ 1 ATOM 570 N NH1 . ARG A 1 73 ? 35.660 11.518 10.862 1.00 35.02 ? 73 ARG A NH1 1 ATOM 571 N NH2 . ARG A 1 73 ? 36.185 10.783 8.746 1.00 36.12 ? 73 ARG A NH2 1 ATOM 572 N N . PHE A 1 74 ? 34.997 5.071 13.485 1.00 14.60 ? 74 PHE A N 1 ATOM 573 C CA . PHE A 1 74 ? 35.846 4.038 14.060 1.00 12.41 ? 74 PHE A CA 1 ATOM 574 C C . PHE A 1 74 ? 37.189 4.012 13.357 1.00 13.67 ? 74 PHE A C 1 ATOM 575 O O . PHE A 1 74 ? 37.252 4.111 12.127 1.00 14.50 ? 74 PHE A O 1 ATOM 576 C CB . PHE A 1 74 ? 35.183 2.672 13.941 1.00 13.56 ? 74 PHE A CB 1 ATOM 577 C CG . PHE A 1 74 ? 33.975 2.506 14.809 1.00 12.34 ? 74 PHE A CG 1 ATOM 578 C CD1 . PHE A 1 74 ? 32.705 2.705 14.296 1.00 12.87 ? 74 PHE A CD1 1 ATOM 579 C CD2 . PHE A 1 74 ? 34.106 2.146 16.137 1.00 12.90 ? 74 PHE A CD2 1 ATOM 580 C CE1 . PHE A 1 74 ? 31.584 2.552 15.095 1.00 13.98 ? 74 PHE A CE1 1 ATOM 581 C CE2 . PHE A 1 74 ? 32.990 1.989 16.943 1.00 14.04 ? 74 PHE A CE2 1 ATOM 582 C CZ . PHE A 1 74 ? 31.727 2.191 16.420 1.00 13.42 ? 74 PHE A CZ 1 ATOM 583 N N A HIS A 1 75 ? 38.260 3.885 14.133 0.39 14.72 ? 75 HIS A N 1 ATOM 584 N N B HIS A 1 75 ? 38.255 3.875 14.144 0.61 15.06 ? 75 HIS A N 1 ATOM 585 C CA A HIS A 1 75 ? 39.600 3.790 13.569 0.39 15.46 ? 75 HIS A CA 1 ATOM 586 C CA B HIS A 1 75 ? 39.618 3.802 13.625 0.61 15.43 ? 75 HIS A CA 1 ATOM 587 C C A HIS A 1 75 ? 40.238 2.440 13.893 0.39 16.46 ? 75 HIS A C 1 ATOM 588 C C B HIS A 1 75 ? 40.244 2.431 13.903 0.61 16.53 ? 75 HIS A C 1 ATOM 589 O O A HIS A 1 75 ? 40.993 2.302 14.861 0.39 17.57 ? 75 HIS A O 1 ATOM 590 O O B HIS A 1 75 ? 41.012 2.270 14.856 0.61 17.81 ? 75 HIS A O 1 ATOM 591 C CB A HIS A 1 75 ? 40.478 4.960 14.029 0.39 16.34 ? 75 HIS A CB 1 ATOM 592 C CB B HIS A 1 75 ? 40.492 4.895 14.249 0.61 16.39 ? 75 HIS A CB 1 ATOM 593 C CG A HIS A 1 75 ? 41.843 4.978 13.410 0.39 17.31 ? 75 HIS A CG 1 ATOM 594 C CG B HIS A 1 75 ? 40.155 6.284 13.801 0.61 16.52 ? 75 HIS A CG 1 ATOM 595 N ND1 A HIS A 1 75 ? 42.947 5.482 14.062 0.39 18.59 ? 75 HIS A ND1 1 ATOM 596 N ND1 B HIS A 1 75 ? 40.567 6.796 12.589 0.61 17.90 ? 75 HIS A ND1 1 ATOM 597 C CD2 A HIS A 1 75 ? 42.283 4.546 12.204 0.39 16.91 ? 75 HIS A CD2 1 ATOM 598 C CD2 B HIS A 1 75 ? 39.479 7.281 14.419 0.61 15.01 ? 75 HIS A CD2 1 ATOM 599 C CE1 A HIS A 1 75 ? 44.007 5.369 13.281 0.39 19.07 ? 75 HIS A CE1 1 ATOM 600 C CE1 B HIS A 1 75 ? 40.144 8.041 12.472 0.61 16.88 ? 75 HIS A CE1 1 ATOM 601 N NE2 A HIS A 1 75 ? 43.631 4.804 12.149 0.39 18.67 ? 75 HIS A NE2 1 ATOM 602 N NE2 B HIS A 1 75 ? 39.484 8.361 13.570 0.61 18.81 ? 75 HIS A NE2 1 ATOM 603 N N . LEU A 1 76 ? 39.908 1.444 13.078 1.00 14.92 ? 76 LEU A N 1 ATOM 604 C CA . LEU A 1 76 ? 40.501 0.120 13.194 1.00 11.98 ? 76 LEU A CA 1 ATOM 605 C C . LEU A 1 76 ? 41.773 0.086 12.369 1.00 15.49 ? 76 LEU A C 1 ATOM 606 O O . LEU A 1 76 ? 41.940 0.890 11.448 1.00 17.16 ? 76 LEU A O 1 ATOM 607 C CB . LEU A 1 76 ? 39.542 -0.946 12.680 1.00 10.22 ? 76 LEU A CB 1 ATOM 608 C CG . LEU A 1 76 ? 38.093 -0.950 13.162 1.00 9.88 ? 76 LEU A CG 1 ATOM 609 C CD1 . LEU A 1 76 ? 37.350 -2.123 12.543 1.00 8.79 ? 76 LEU A CD1 1 ATOM 610 C CD2 . LEU A 1 76 ? 38.012 -1.016 14.677 1.00 15.09 ? 76 LEU A CD2 1 ATOM 611 N N . ARG A 1 77 ? 42.680 -0.823 12.709 1.00 14.30 ? 77 ARG A N 1 ATOM 612 C CA . ARG A 1 77 ? 43.789 -1.151 11.816 1.00 15.23 ? 77 ARG A CA 1 ATOM 613 C C . ARG A 1 77 ? 43.828 -2.660 11.594 1.00 16.26 ? 77 ARG A C 1 ATOM 614 O O . ARG A 1 77 ? 43.435 -3.427 12.477 1.00 16.48 ? 77 ARG A O 1 ATOM 615 C CB . ARG A 1 77 ? 45.133 -0.585 12.301 1.00 15.28 ? 77 ARG A CB 1 ATOM 616 C CG . ARG A 1 77 ? 45.356 -0.636 13.808 1.00 25.27 ? 77 ARG A CG 1 ATOM 617 C CD . ARG A 1 77 ? 46.813 -0.336 14.206 1.00 28.86 ? 77 ARG A CD 1 ATOM 618 N NE . ARG A 1 77 ? 47.221 1.047 13.946 1.00 39.02 ? 77 ARG A NE 1 ATOM 619 C CZ . ARG A 1 77 ? 48.154 1.422 13.067 1.00 41.40 ? 77 ARG A CZ 1 ATOM 620 N NH1 . ARG A 1 77 ? 48.442 2.713 12.914 1.00 42.28 ? 77 ARG A NH1 1 ATOM 621 N NH2 . ARG A 1 77 ? 48.809 0.519 12.343 1.00 25.45 ? 77 ARG A NH2 1 ATOM 622 N N . ALA A 1 78 ? 44.270 -3.072 10.404 1.00 17.23 ? 78 ALA A N 1 ATOM 623 C CA . ALA A 1 78 ? 44.221 -4.478 9.983 1.00 14.32 ? 78 ALA A CA 1 ATOM 624 C C . ALA A 1 78 ? 45.601 -5.138 9.916 1.00 15.92 ? 78 ALA A C 1 ATOM 625 O O . ALA A 1 78 ? 46.583 -4.512 9.510 1.00 15.77 ? 78 ALA A O 1 ATOM 626 C CB . ALA A 1 78 ? 43.517 -4.598 8.655 1.00 13.40 ? 78 ALA A CB 1 ATOM 627 N N . HIS A 1 79 ? 45.652 -6.412 10.299 1.00 16.79 ? 79 HIS A N 1 ATOM 628 C CA . HIS A 1 79 ? 46.908 -7.145 10.456 1.00 12.61 ? 79 HIS A CA 1 ATOM 629 C C . HIS A 1 79 ? 46.997 -8.346 9.521 1.00 15.06 ? 79 HIS A C 1 ATOM 630 O O . HIS A 1 79 ? 45.972 -8.899 9.111 1.00 18.43 ? 79 HIS A O 1 ATOM 631 C CB . HIS A 1 79 ? 47.050 -7.613 11.904 1.00 14.88 ? 79 HIS A CB 1 ATOM 632 C CG . HIS A 1 79 ? 47.140 -6.494 12.895 1.00 18.47 ? 79 HIS A CG 1 ATOM 633 N ND1 . HIS A 1 79 ? 48.330 -6.102 13.467 1.00 17.55 ? 79 HIS A ND1 1 ATOM 634 C CD2 . HIS A 1 79 ? 46.188 -5.681 13.412 1.00 16.85 ? 79 HIS A CD2 1 ATOM 635 C CE1 . HIS A 1 79 ? 48.107 -5.098 14.296 1.00 16.71 ? 79 HIS A CE1 1 ATOM 636 N NE2 . HIS A 1 79 ? 46.815 -4.821 14.279 1.00 13.83 ? 79 HIS A NE2 1 ATOM 637 N N . ALA A 1 80 ? 48.222 -8.752 9.190 1.00 15.59 ? 80 ALA A N 1 ATOM 638 C CA . ALA A 1 80 ? 48.444 -9.914 8.323 1.00 14.62 ? 80 ALA A CA 1 ATOM 639 C C . ALA A 1 80 ? 49.648 -10.740 8.767 1.00 16.93 ? 80 ALA A C 1 ATOM 640 O O . ALA A 1 80 ? 50.759 -10.215 8.883 1.00 20.09 ? 80 ALA A O 1 ATOM 641 C CB . ALA A 1 80 ? 48.600 -9.476 6.879 1.00 12.21 ? 80 ALA A CB 1 ATOM 642 N N . VAL A 1 81 ? 49.419 -12.030 9.014 1.00 17.20 ? 81 VAL A N 1 ATOM 643 C CA . VAL A 1 81 ? 50.476 -12.958 9.433 1.00 16.75 ? 81 VAL A CA 1 ATOM 644 C C . VAL A 1 81 ? 50.307 -14.338 8.813 1.00 16.78 ? 81 VAL A C 1 ATOM 645 O O . VAL A 1 81 ? 49.204 -14.887 8.820 1.00 17.12 ? 81 VAL A O 1 ATOM 646 C CB . VAL A 1 81 ? 50.540 -13.119 10.970 1.00 15.56 ? 81 VAL A CB 1 ATOM 647 C CG1 . VAL A 1 81 ? 51.458 -12.081 11.578 1.00 18.14 ? 81 VAL A CG1 1 ATOM 648 C CG2 . VAL A 1 81 ? 49.154 -13.034 11.586 1.00 17.90 ? 81 VAL A CG2 1 ATOM 649 N N . ASP A 1 82 ? 51.399 -14.891 8.283 1.00 17.19 ? 82 ASP A N 1 ATOM 650 C CA . ASP A 1 82 ? 51.401 -16.259 7.742 1.00 17.92 ? 82 ASP A CA 1 ATOM 651 C C . ASP A 1 82 ? 51.322 -17.295 8.862 1.00 21.20 ? 82 ASP A C 1 ATOM 652 O O . ASP A 1 82 ? 51.551 -16.965 10.031 1.00 26.92 ? 82 ASP A O 1 ATOM 653 C CB . ASP A 1 82 ? 52.625 -16.508 6.843 1.00 22.79 ? 82 ASP A CB 1 ATOM 654 C CG . ASP A 1 82 ? 53.971 -16.334 7.574 1.00 27.42 ? 82 ASP A CG 1 ATOM 655 O OD1 . ASP A 1 82 ? 54.021 -16.388 8.825 1.00 26.32 ? 82 ASP A OD1 1 ATOM 656 O OD2 . ASP A 1 82 ? 54.999 -16.153 6.875 1.00 25.90 ? 82 ASP A OD2 1 ATOM 657 N N . ILE A 1 83 ? 51.010 -18.541 8.513 1.00 15.65 ? 83 ILE A N 1 ATOM 658 C CA . ILE A 1 83 ? 50.815 -19.587 9.521 1.00 15.64 ? 83 ILE A CA 1 ATOM 659 C C . ILE A 1 83 ? 52.079 -19.949 10.309 1.00 21.43 ? 83 ILE A C 1 ATOM 660 O O . ILE A 1 83 ? 52.009 -20.700 11.283 1.00 24.10 ? 83 ILE A O 1 ATOM 661 C CB . ILE A 1 83 ? 50.191 -20.881 8.937 1.00 15.07 ? 83 ILE A CB 1 ATOM 662 C CG1 . ILE A 1 83 ? 51.194 -21.643 8.045 1.00 22.31 ? 83 ILE A CG1 1 ATOM 663 C CG2 . ILE A 1 83 ? 48.845 -20.597 8.271 1.00 18.18 ? 83 ILE A CG2 1 ATOM 664 C CD1 . ILE A 1 83 ? 51.338 -21.145 6.597 1.00 29.84 ? 83 ILE A CD1 1 ATOM 665 N N . ASN A 1 84 ? 53.226 -19.425 9.886 1.00 23.58 ? 84 ASN A N 1 ATOM 666 C CA . ASN A 1 84 ? 54.478 -19.636 10.615 1.00 23.46 ? 84 ASN A CA 1 ATOM 667 C C . ASN A 1 84 ? 54.894 -18.435 11.461 1.00 23.94 ? 84 ASN A C 1 ATOM 668 O O . ASN A 1 84 ? 56.062 -18.298 11.849 1.00 22.26 ? 84 ASN A O 1 ATOM 669 C CB . ASN A 1 84 ? 55.593 -20.075 9.663 1.00 24.67 ? 84 ASN A CB 1 ATOM 670 C CG . ASN A 1 84 ? 55.400 -21.499 9.160 1.00 29.10 ? 84 ASN A CG 1 ATOM 671 O OD1 . ASN A 1 84 ? 54.902 -22.371 9.885 1.00 25.81 ? 84 ASN A OD1 1 ATOM 672 N ND2 . ASN A 1 84 ? 55.795 -21.742 7.914 1.00 34.55 ? 84 ASN A ND2 1 ATOM 673 N N . GLY A 1 85 ? 53.921 -17.570 11.739 1.00 24.98 ? 85 GLY A N 1 ATOM 674 C CA . GLY A 1 85 ? 54.098 -16.463 12.670 1.00 22.96 ? 85 GLY A CA 1 ATOM 675 C C . GLY A 1 85 ? 54.730 -15.191 12.134 1.00 24.96 ? 85 GLY A C 1 ATOM 676 O O . GLY A 1 85 ? 54.881 -14.220 12.879 1.00 31.29 ? 85 GLY A O 1 ATOM 677 N N . ASN A 1 86 ? 55.103 -15.177 10.857 1.00 19.23 ? 86 ASN A N 1 ATOM 678 C CA . ASN A 1 86 ? 55.738 -13.992 10.285 1.00 19.15 ? 86 ASN A CA 1 ATOM 679 C C . ASN A 1 86 ? 54.738 -12.901 9.949 1.00 22.31 ? 86 ASN A C 1 ATOM 680 O O . ASN A 1 86 ? 53.706 -13.159 9.321 1.00 24.35 ? 86 ASN A O 1 ATOM 681 C CB . ASN A 1 86 ? 56.537 -14.340 9.030 1.00 23.67 ? 86 ASN A CB 1 ATOM 682 C CG . ASN A 1 86 ? 57.641 -15.322 9.300 1.00 26.95 ? 86 ASN A CG 1 ATOM 683 O OD1 . ASN A 1 86 ? 58.532 -15.063 10.110 1.00 28.17 ? 86 ASN A OD1 1 ATOM 684 N ND2 . ASN A 1 86 ? 57.600 -16.462 8.615 1.00 27.02 ? 86 ASN A ND2 1 ATOM 685 N N . GLN A 1 87 ? 55.054 -11.684 10.376 1.00 18.33 ? 87 GLN A N 1 ATOM 686 C CA . GLN A 1 87 ? 54.330 -10.503 9.941 1.00 17.23 ? 87 GLN A CA 1 ATOM 687 C C . GLN A 1 87 ? 54.662 -10.262 8.472 1.00 19.00 ? 87 GLN A C 1 ATOM 688 O O . GLN A 1 87 ? 55.816 -10.026 8.120 1.00 20.63 ? 87 GLN A O 1 ATOM 689 C CB . GLN A 1 87 ? 54.723 -9.302 10.806 1.00 20.48 ? 87 GLN A CB 1 ATOM 690 C CG . GLN A 1 87 ? 54.217 -7.954 10.312 1.00 26.05 ? 87 GLN A CG 1 ATOM 691 C CD . GLN A 1 87 ? 53.947 -6.981 11.445 1.00 31.55 ? 87 GLN A CD 1 ATOM 692 O OE1 . GLN A 1 87 ? 53.308 -7.330 12.443 1.00 36.44 ? 87 GLN A OE1 1 ATOM 693 N NE2 . GLN A 1 87 ? 54.418 -5.745 11.290 1.00 29.97 ? 87 GLN A NE2 1 ATOM 694 N N . VAL A 1 88 ? 53.652 -10.343 7.617 1.00 17.58 ? 88 VAL A N 1 ATOM 695 C CA . VAL A 1 88 ? 53.862 -10.195 6.178 1.00 18.21 ? 88 VAL A CA 1 ATOM 696 C C . VAL A 1 88 ? 53.558 -8.787 5.675 1.00 20.45 ? 88 VAL A C 1 ATOM 697 O O . VAL A 1 88 ? 54.114 -8.355 4.664 1.00 25.91 ? 88 VAL A O 1 ATOM 698 C CB . VAL A 1 88 ? 53.063 -11.231 5.361 1.00 16.54 ? 88 VAL A CB 1 ATOM 699 C CG1 . VAL A 1 88 ? 53.615 -12.626 5.593 1.00 19.92 ? 88 VAL A CG1 1 ATOM 700 C CG2 . VAL A 1 88 ? 51.592 -11.174 5.714 1.00 18.14 ? 88 VAL A CG2 1 ATOM 701 N N . GLU A 1 89 ? 52.668 -8.087 6.377 1.00 21.09 ? 89 GLU A N 1 ATOM 702 C CA . GLU A 1 89 ? 52.346 -6.688 6.079 1.00 21.65 ? 89 GLU A CA 1 ATOM 703 C C . GLU A 1 89 ? 52.344 -5.837 7.343 1.00 20.60 ? 89 GLU A C 1 ATOM 704 O O . GLU A 1 89 ? 51.924 -6.285 8.416 1.00 16.94 ? 89 GLU A O 1 ATOM 705 C CB . GLU A 1 89 ? 50.974 -6.561 5.411 1.00 15.48 ? 89 GLU A CB 1 ATOM 706 C CG . GLU A 1 89 ? 50.765 -7.387 4.161 1.00 13.77 ? 89 GLU A CG 1 ATOM 707 C CD . GLU A 1 89 ? 51.422 -6.803 2.924 1.00 20.08 ? 89 GLU A CD 1 ATOM 708 O OE1 . GLU A 1 89 ? 52.115 -5.766 3.018 1.00 21.88 ? 89 GLU A OE1 1 ATOM 709 O OE2 . GLU A 1 89 ? 51.244 -7.394 1.842 1.00 18.09 ? 89 GLU A OE2 1 ATOM 710 N N . ASN A 1 90 ? 52.807 -4.601 7.205 1.00 19.17 ? 90 ASN A N 1 ATOM 711 C CA . ASN A 1 90 ? 52.679 -3.629 8.275 1.00 18.34 ? 90 ASN A CA 1 ATOM 712 C C . ASN A 1 90 ? 51.207 -3.333 8.480 1.00 18.66 ? 90 ASN A C 1 ATOM 713 O O . ASN A 1 90 ? 50.465 -3.202 7.501 1.00 20.62 ? 90 ASN A O 1 ATOM 714 C CB . ASN A 1 90 ? 53.438 -2.352 7.936 1.00 20.83 ? 90 ASN A CB 1 ATOM 715 C CG . ASN A 1 90 ? 54.932 -2.577 7.837 1.00 28.30 ? 90 ASN A CG 1 ATOM 716 O OD1 . ASN A 1 90 ? 55.529 -3.271 8.666 1.00 31.21 ? 90 ASN A OD1 1 ATOM 717 N ND2 . ASN A 1 90 ? 55.549 -1.988 6.819 1.00 36.09 ? 90 ASN A ND2 1 ATOM 718 N N . PRO A 1 91 ? 50.772 -3.247 9.750 1.00 14.53 ? 91 PRO A N 1 ATOM 719 C CA . PRO A 1 91 ? 49.370 -2.995 10.044 1.00 13.10 ? 91 PRO A CA 1 ATOM 720 C C . PRO A 1 91 ? 48.907 -1.763 9.299 1.00 14.70 ? 91 PRO A C 1 ATOM 721 O O . PRO A 1 91 ? 49.666 -0.804 9.162 1.00 15.75 ? 91 PRO A O 1 ATOM 722 C CB . PRO A 1 91 ? 49.368 -2.745 11.547 1.00 15.49 ? 91 PRO A CB 1 ATOM 723 C CG . PRO A 1 91 ? 50.533 -3.487 12.046 1.00 15.99 ? 91 PRO A CG 1 ATOM 724 C CD . PRO A 1 91 ? 51.572 -3.379 10.978 1.00 17.62 ? 91 PRO A CD 1 ATOM 725 N N . ILE A 1 92 ? 47.681 -1.804 8.798 1.00 14.99 ? 92 ILE A N 1 ATOM 726 C CA . ILE A 1 92 ? 47.189 -0.731 7.948 1.00 16.87 ? 92 ILE A CA 1 ATOM 727 C C . ILE A 1 92 ? 45.875 -0.154 8.463 1.00 17.56 ? 92 ILE A C 1 ATOM 728 O O . ILE A 1 92 ? 45.010 -0.893 8.931 1.00 16.25 ? 92 ILE A O 1 ATOM 729 C CB . ILE A 1 92 ? 47.097 -1.180 6.469 1.00 13.72 ? 92 ILE A CB 1 ATOM 730 C CG1 . ILE A 1 92 ? 47.098 0.040 5.549 1.00 11.97 ? 92 ILE A CG1 1 ATOM 731 C CG2 . ILE A 1 92 ? 45.895 -2.104 6.230 1.00 13.88 ? 92 ILE A CG2 1 ATOM 732 C CD1 . ILE A 1 92 ? 47.860 -0.173 4.266 1.00 15.56 ? 92 ILE A CD1 1 ATOM 733 N N . ASP A 1 93 ? 45.749 1.170 8.378 1.00 16.74 ? 93 ASP A N 1 ATOM 734 C CA . ASP A 1 93 ? 44.607 1.883 8.946 1.00 15.87 ? 93 ASP A CA 1 ATOM 735 C C . ASP A 1 93 ? 43.349 1.710 8.113 1.00 16.90 ? 93 ASP A C 1 ATOM 736 O O . ASP A 1 93 ? 43.393 1.782 6.877 1.00 21.72 ? 93 ASP A O 1 ATOM 737 C CB . ASP A 1 93 ? 44.928 3.371 9.116 1.00 19.18 ? 93 ASP A CB 1 ATOM 738 C CG . ASP A 1 93 ? 45.870 3.641 10.285 1.00 28.77 ? 93 ASP A CG 1 ATOM 739 O OD1 . ASP A 1 93 ? 45.619 3.113 11.394 1.00 30.88 ? 93 ASP A OD1 1 ATOM 740 O OD2 . ASP A 1 93 ? 46.855 4.392 10.102 1.00 31.62 ? 93 ASP A OD2 1 ATOM 741 N N . ILE A 1 94 ? 42.232 1.478 8.798 1.00 14.04 ? 94 ILE A N 1 ATOM 742 C CA . ILE A 1 94 ? 40.932 1.325 8.143 1.00 14.17 ? 94 ILE A CA 1 ATOM 743 C C . ILE A 1 94 ? 39.834 2.051 8.922 1.00 14.88 ? 94 ILE A C 1 ATOM 744 O O . ILE A 1 94 ? 39.711 1.892 10.135 1.00 17.69 ? 94 ILE A O 1 ATOM 745 C CB . ILE A 1 94 ? 40.592 -0.163 7.874 1.00 12.34 ? 94 ILE A CB 1 ATOM 746 C CG1 . ILE A 1 94 ? 39.080 -0.392 7.862 1.00 15.19 ? 94 ILE A CG1 1 ATOM 747 C CG2 . ILE A 1 94 ? 41.243 -1.059 8.902 1.00 17.86 ? 94 ILE A CG2 1 ATOM 748 C CD1 . ILE A 1 94 ? 38.674 -1.704 7.233 1.00 21.09 ? 94 ILE A CD1 1 ATOM 749 N N . VAL A 1 95 ? 39.046 2.854 8.211 1.00 12.02 ? 95 VAL A N 1 ATOM 750 C CA . VAL A 1 95 ? 38.117 3.794 8.836 1.00 9.98 ? 95 VAL A CA 1 ATOM 751 C C . VAL A 1 95 ? 36.657 3.460 8.533 1.00 13.48 ? 95 VAL A C 1 ATOM 752 O O . VAL A 1 95 ? 36.284 3.222 7.379 1.00 15.79 ? 95 VAL A O 1 ATOM 753 C CB . VAL A 1 95 ? 38.387 5.226 8.339 1.00 8.13 ? 95 VAL A CB 1 ATOM 754 C CG1 . VAL A 1 95 ? 37.533 6.221 9.083 1.00 13.18 ? 95 VAL A CG1 1 ATOM 755 C CG2 . VAL A 1 95 ? 39.854 5.575 8.482 1.00 12.32 ? 95 VAL A CG2 1 ATOM 756 N N . ILE A 1 96 ? 35.827 3.448 9.567 1.00 10.22 ? 96 ILE A N 1 ATOM 757 C CA . ILE A 1 96 ? 34.394 3.349 9.346 1.00 9.04 ? 96 ILE A CA 1 ATOM 758 C C . ILE A 1 96 ? 33.744 4.654 9.765 1.00 11.67 ? 96 ILE A C 1 ATOM 759 O O . ILE A 1 96 ? 33.800 5.048 10.931 1.00 14.42 ? 96 ILE A O 1 ATOM 760 C CB . ILE A 1 96 ? 33.743 2.155 10.086 1.00 12.24 ? 96 ILE A CB 1 ATOM 761 C CG1 . ILE A 1 96 ? 34.311 0.824 9.592 1.00 10.93 ? 96 ILE A CG1 1 ATOM 762 C CG2 . ILE A 1 96 ? 32.234 2.153 9.884 1.00 12.84 ? 96 ILE A CG2 1 ATOM 763 C CD1 . ILE A 1 96 ? 35.345 0.234 10.503 1.00 10.58 ? 96 ILE A CD1 1 ATOM 764 N N . ASN A 1 97 ? 33.159 5.333 8.789 1.00 12.07 ? 97 ASN A N 1 ATOM 765 C CA . ASN A 1 97 ? 32.341 6.500 9.034 1.00 8.74 ? 97 ASN A CA 1 ATOM 766 C C . ASN A 1 97 ? 30.908 6.046 9.209 1.00 10.46 ? 97 ASN A C 1 ATOM 767 O O . ASN A 1 97 ? 30.346 5.399 8.323 1.00 12.11 ? 97 ASN A O 1 ATOM 768 C CB . ASN A 1 97 ? 32.423 7.451 7.842 1.00 8.94 ? 97 ASN A CB 1 ATOM 769 C CG . ASN A 1 97 ? 33.736 8.193 7.774 1.00 11.44 ? 97 ASN A CG 1 ATOM 770 O OD1 . ASN A 1 97 ? 34.137 8.858 8.726 1.00 15.96 ? 97 ASN A OD1 1 ATOM 771 N ND2 . ASN A 1 97 ? 34.404 8.106 6.636 1.00 10.52 ? 97 ASN A ND2 1 ATOM 772 N N . VAL A 1 98 ? 30.311 6.356 10.352 1.00 10.76 ? 98 VAL A N 1 ATOM 773 C CA . VAL A 1 98 ? 28.886 6.099 10.498 1.00 10.99 ? 98 VAL A CA 1 ATOM 774 C C . VAL A 1 98 ? 28.078 7.329 10.098 1.00 10.72 ? 98 VAL A C 1 ATOM 775 O O . VAL A 1 98 ? 28.230 8.408 10.660 1.00 10.50 ? 98 VAL A O 1 ATOM 776 C CB . VAL A 1 98 ? 28.483 5.490 11.867 1.00 11.13 ? 98 VAL A CB 1 ATOM 777 C CG1 . VAL A 1 98 ? 29.142 6.191 12.995 1.00 11.64 ? 98 VAL A CG1 1 ATOM 778 C CG2 . VAL A 1 98 ? 26.978 5.507 12.039 1.00 14.82 ? 98 VAL A CG2 1 ATOM 779 N N . ILE A 1 99 ? 27.239 7.126 9.090 1.00 13.48 ? 99 ILE A N 1 ATOM 780 C CA . ILE A 1 99 ? 26.520 8.178 8.397 1.00 11.74 ? 99 ILE A CA 1 ATOM 781 C C . ILE A 1 99 ? 25.192 8.442 9.078 1.00 14.32 ? 99 ILE A C 1 ATOM 782 O O . ILE A 1 99 ? 24.501 7.504 9.479 1.00 15.47 ? 99 ILE A O 1 ATOM 783 C CB . ILE A 1 99 ? 26.310 7.778 6.928 1.00 10.06 ? 99 ILE A CB 1 ATOM 784 C CG1 . ILE A 1 99 ? 27.613 7.991 6.152 1.00 10.30 ? 99 ILE A CG1 1 ATOM 785 C CG2 . ILE A 1 99 ? 25.138 8.535 6.302 1.00 15.65 ? 99 ILE A CG2 1 ATOM 786 C CD1 . ILE A 1 99 ? 27.621 7.367 4.765 1.00 18.92 ? 99 ILE A CD1 1 ATOM 787 N N . ASP A 1 100 ? 24.836 9.720 9.192 1.00 17.18 ? 100 ASP A N 1 ATOM 788 C CA . ASP A 1 100 ? 23.697 10.127 10.009 1.00 20.25 ? 100 ASP A CA 1 ATOM 789 C C . ASP A 1 100 ? 22.330 9.770 9.458 1.00 19.08 ? 100 ASP A C 1 ATOM 790 O O . ASP A 1 100 ? 22.086 9.823 8.254 1.00 17.42 ? 100 ASP A O 1 ATOM 791 C CB . ASP A 1 100 ? 23.735 11.623 10.316 1.00 23.96 ? 100 ASP A CB 1 ATOM 792 C CG . ASP A 1 100 ? 22.773 12.014 11.437 1.00 26.52 ? 100 ASP A CG 1 ATOM 793 O OD1 . ASP A 1 100 ? 22.696 11.288 12.457 1.00 22.13 ? 100 ASP A OD1 1 ATOM 794 O OD2 . ASP A 1 100 ? 22.091 13.051 11.299 1.00 30.27 ? 100 ASP A OD2 1 ATOM 795 N N . MET A 1 101 ? 21.454 9.400 10.384 1.00 19.02 ? 101 MET A N 1 ATOM 796 C CA . MET A 1 101 ? 20.041 9.222 10.121 1.00 22.73 ? 101 MET A CA 1 ATOM 797 C C . MET A 1 101 ? 19.253 10.127 11.060 1.00 26.93 ? 101 MET A C 1 ATOM 798 O O . MET A 1 101 ? 19.715 10.452 12.161 1.00 23.82 ? 101 MET A O 1 ATOM 799 C CB . MET A 1 101 ? 19.639 7.765 10.333 1.00 20.73 ? 101 MET A CB 1 ATOM 800 C CG . MET A 1 101 ? 20.307 6.804 9.375 1.00 19.13 ? 101 MET A CG 1 ATOM 801 S SD . MET A 1 101 ? 19.684 6.970 7.698 1.00 28.22 ? 101 MET A SD 1 ATOM 802 C CE . MET A 1 101 ? 18.054 6.231 7.880 1.00 21.75 ? 101 MET A CE 1 ATOM 803 N N . ASN A 1 102 ? 18.069 10.538 10.621 1.00 24.74 ? 102 ASN A N 1 ATOM 804 C CA . ASN A 1 102 ? 17.238 11.410 11.428 1.00 23.95 ? 102 ASN A CA 1 ATOM 805 C C . ASN A 1 102 ? 16.452 10.603 12.440 1.00 24.62 ? 102 ASN A C 1 ATOM 806 O O . ASN A 1 102 ? 15.275 10.306 12.226 1.00 28.86 ? 102 ASN A O 1 ATOM 807 C CB . ASN A 1 102 ? 16.293 12.225 10.549 1.00 28.72 ? 102 ASN A CB 1 ATOM 808 C CG . ASN A 1 102 ? 15.643 13.367 11.300 1.00 28.60 ? 102 ASN A CG 1 ATOM 809 O OD1 . ASN A 1 102 ? 16.265 14.000 12.155 1.00 26.10 ? 102 ASN A OD1 1 ATOM 810 N ND2 . ASN A 1 102 ? 14.383 13.637 10.985 1.00 31.49 ? 102 ASN A ND2 1 ATOM 811 N N . ASP A 1 103 ? 17.112 10.240 13.536 1.00 23.25 ? 103 ASP A N 1 ATOM 812 C CA . ASP A 1 103 ? 16.486 9.425 14.576 1.00 22.06 ? 103 ASP A CA 1 ATOM 813 C C . ASP A 1 103 ? 16.413 10.157 15.915 1.00 27.87 ? 103 ASP A C 1 ATOM 814 O O . ASP A 1 103 ? 16.165 9.547 16.958 1.00 27.82 ? 103 ASP A O 1 ATOM 815 C CB . ASP A 1 103 ? 17.203 8.074 14.717 1.00 21.97 ? 103 ASP A CB 1 ATOM 816 C CG . ASP A 1 103 ? 18.683 8.213 15.077 1.00 25.04 ? 103 ASP A CG 1 ATOM 817 O OD1 . ASP A 1 103 ? 19.309 9.245 14.748 1.00 23.50 ? 103 ASP A OD1 1 ATOM 818 O OD2 . ASP A 1 103 ? 19.236 7.272 15.689 1.00 25.57 ? 103 ASP A OD2 1 ATOM 819 N N . ASN A 1 104 ? 16.627 11.470 15.876 1.00 27.97 ? 104 ASN A N 1 ATOM 820 C CA . ASN A 1 104 ? 16.507 12.303 17.067 1.00 25.09 ? 104 ASN A CA 1 ATOM 821 C C . ASN A 1 104 ? 15.583 13.494 16.871 1.00 28.43 ? 104 ASN A C 1 ATOM 822 O O . ASN A 1 104 ? 15.798 14.329 15.987 1.00 28.10 ? 104 ASN A O 1 ATOM 823 C CB . ASN A 1 104 ? 17.879 12.782 17.537 1.00 24.07 ? 104 ASN A CB 1 ATOM 824 C CG . ASN A 1 104 ? 18.721 11.666 18.081 1.00 22.93 ? 104 ASN A CG 1 ATOM 825 O OD1 . ASN A 1 104 ? 19.118 10.759 17.353 1.00 27.81 ? 104 ASN A OD1 1 ATOM 826 N ND2 . ASN A 1 104 ? 19.006 11.724 19.373 1.00 22.13 ? 104 ASN A ND2 1 ATOM 827 N N . ARG A 1 105 ? 14.552 13.558 17.706 1.00 28.56 ? 105 ARG A N 1 ATOM 828 C CA . ARG A 1 105 ? 13.657 14.702 17.752 1.00 28.02 ? 105 ARG A CA 1 ATOM 829 C C . ARG A 1 105 ? 14.365 15.874 18.423 1.00 29.17 ? 105 ARG A C 1 ATOM 830 O O . ARG A 1 105 ? 15.208 15.663 19.297 1.00 30.76 ? 105 ARG A O 1 ATOM 831 C CB . ARG A 1 105 ? 12.381 14.343 18.511 1.00 28.44 ? 105 ARG A CB 1 ATOM 832 C CG . ARG A 1 105 ? 11.564 13.243 17.838 1.00 39.90 ? 105 ARG A CG 1 ATOM 833 C CD . ARG A 1 105 ? 10.074 13.323 18.168 1.00 40.63 ? 105 ARG A CD 1 ATOM 834 N NE . ARG A 1 105 ? 9.747 12.709 19.452 1.00 39.01 ? 105 ARG A NE 1 ATOM 835 C CZ . ARG A 1 105 ? 9.826 13.329 20.626 1.00 45.55 ? 105 ARG A CZ 1 ATOM 836 N NH1 . ARG A 1 105 ? 10.231 14.591 20.698 1.00 40.20 ? 105 ARG A NH1 1 ATOM 837 N NH2 . ARG A 1 105 ? 9.505 12.680 21.736 1.00 60.26 ? 105 ARG A NH2 1 ATOM 838 N N . PRO A 1 106 ? 14.040 17.115 18.009 1.00 27.80 ? 106 PRO A N 1 ATOM 839 C CA . PRO A 1 106 ? 14.625 18.296 18.639 1.00 24.91 ? 106 PRO A CA 1 ATOM 840 C C . PRO A 1 106 ? 14.269 18.374 20.118 1.00 25.36 ? 106 PRO A C 1 ATOM 841 O O . PRO A 1 106 ? 13.213 17.900 20.523 1.00 28.84 ? 106 PRO A O 1 ATOM 842 C CB . PRO A 1 106 ? 13.970 19.452 17.882 1.00 21.70 ? 106 PRO A CB 1 ATOM 843 C CG . PRO A 1 106 ? 13.549 18.871 16.591 1.00 24.64 ? 106 PRO A CG 1 ATOM 844 C CD . PRO A 1 106 ? 13.120 17.486 16.921 1.00 27.40 ? 106 PRO A CD 1 ATOM 845 N N . GLU A 1 107 ? 15.153 18.952 20.919 1.00 25.88 ? 107 GLU A N 1 ATOM 846 C CA . GLU A 1 107 ? 14.912 19.071 22.352 1.00 29.49 ? 107 GLU A CA 1 ATOM 847 C C . GLU A 1 107 ? 15.129 20.503 22.798 1.00 31.78 ? 107 GLU A C 1 ATOM 848 O O . GLU A 1 107 ? 16.029 21.186 22.299 1.00 34.05 ? 107 GLU A O 1 ATOM 849 C CB . GLU A 1 107 ? 15.843 18.145 23.146 1.00 39.09 ? 107 GLU A CB 1 ATOM 850 C CG . GLU A 1 107 ? 15.655 16.648 22.884 1.00 44.05 ? 107 GLU A CG 1 ATOM 851 C CD . GLU A 1 107 ? 14.368 16.092 23.473 1.00 48.06 ? 107 GLU A CD 1 ATOM 852 O OE1 . GLU A 1 107 ? 13.694 15.294 22.781 1.00 42.73 ? 107 GLU A OE1 1 ATOM 853 O OE2 . GLU A 1 107 ? 14.033 16.449 24.627 1.00 52.94 ? 107 GLU A OE2 1 ATOM 854 N N . PHE A 1 108 ? 14.303 20.951 23.737 1.00 29.41 ? 108 PHE A N 1 ATOM 855 C CA . PHE A 1 108 ? 14.458 22.277 24.317 1.00 33.98 ? 108 PHE A CA 1 ATOM 856 C C . PHE A 1 108 ? 15.182 22.211 25.657 1.00 37.22 ? 108 PHE A C 1 ATOM 857 O O . PHE A 1 108 ? 14.879 21.355 26.498 1.00 33.02 ? 108 PHE A O 1 ATOM 858 C CB . PHE A 1 108 ? 13.097 22.953 24.489 1.00 38.06 ? 108 PHE A CB 1 ATOM 859 C CG . PHE A 1 108 ? 12.517 23.484 23.215 1.00 28.61 ? 108 PHE A CG 1 ATOM 860 C CD1 . PHE A 1 108 ? 12.906 24.723 22.725 1.00 27.54 ? 108 PHE A CD1 1 ATOM 861 C CD2 . PHE A 1 108 ? 11.573 22.750 22.508 1.00 26.75 ? 108 PHE A CD2 1 ATOM 862 C CE1 . PHE A 1 108 ? 12.368 25.222 21.546 1.00 29.67 ? 108 PHE A CE1 1 ATOM 863 C CE2 . PHE A 1 108 ? 11.028 23.241 21.331 1.00 26.45 ? 108 PHE A CE2 1 ATOM 864 C CZ . PHE A 1 108 ? 11.426 24.478 20.848 1.00 25.71 ? 108 PHE A CZ 1 ATOM 865 N N . LEU A 1 109 ? 16.138 23.121 25.839 1.00 39.10 ? 109 LEU A N 1 ATOM 866 C CA . LEU A 1 109 ? 16.910 23.244 27.082 1.00 44.78 ? 109 LEU A CA 1 ATOM 867 C C . LEU A 1 109 ? 15.982 23.297 28.295 1.00 44.75 ? 109 LEU A C 1 ATOM 868 O O . LEU A 1 109 ? 16.069 22.455 29.192 1.00 47.61 ? 109 LEU A O 1 ATOM 869 C CB . LEU A 1 109 ? 17.799 24.496 27.052 1.00 43.57 ? 109 LEU A CB 1 ATOM 870 C CG . LEU A 1 109 ? 18.870 24.698 25.968 1.00 50.34 ? 109 LEU A CG 1 ATOM 871 C CD1 . LEU A 1 109 ? 18.281 24.882 24.564 1.00 37.55 ? 109 LEU A CD1 1 ATOM 872 C CD2 . LEU A 1 109 ? 19.744 25.893 26.337 1.00 52.52 ? 109 LEU A CD2 1 ATOM 873 N N . HIS A 1 110 ? 15.093 24.288 28.311 1.00 41.43 ? 110 HIS A N 1 ATOM 874 C CA . HIS A 1 110 ? 14.054 24.382 29.330 1.00 37.68 ? 110 HIS A CA 1 ATOM 875 C C . HIS A 1 110 ? 12.746 23.928 28.708 1.00 33.47 ? 110 HIS A C 1 ATOM 876 O O . HIS A 1 110 ? 12.579 23.992 27.491 1.00 31.21 ? 110 HIS A O 1 ATOM 877 C CB . HIS A 1 110 ? 13.909 25.818 29.844 1.00 33.39 ? 110 HIS A CB 1 ATOM 878 C CG . HIS A 1 110 ? 15.176 26.610 29.787 1.00 38.50 ? 110 HIS A CG 1 ATOM 879 N ND1 . HIS A 1 110 ? 16.232 26.389 30.644 1.00 50.04 ? 110 HIS A ND1 1 ATOM 880 C CD2 . HIS A 1 110 ? 15.562 27.616 28.967 1.00 41.50 ? 110 HIS A CD2 1 ATOM 881 C CE1 . HIS A 1 110 ? 17.211 27.229 30.360 1.00 51.32 ? 110 HIS A CE1 1 ATOM 882 N NE2 . HIS A 1 110 ? 16.831 27.985 29.346 1.00 47.50 ? 110 HIS A NE2 1 ATOM 883 N N . GLN A 1 111 ? 11.825 23.464 29.544 1.00 35.76 ? 111 GLN A N 1 ATOM 884 C CA . GLN A 1 111 ? 10.485 23.137 29.087 1.00 31.42 ? 111 GLN A CA 1 ATOM 885 C C . GLN A 1 111 ? 9.543 24.324 29.289 1.00 35.06 ? 111 GLN A C 1 ATOM 886 O O . GLN A 1 111 ? 8.427 24.334 28.768 1.00 37.98 ? 111 GLN A O 1 ATOM 887 C CB . GLN A 1 111 ? 9.961 21.881 29.788 1.00 26.60 ? 111 GLN A CB 1 ATOM 888 C CG . GLN A 1 111 ? 8.924 21.102 28.982 1.00 29.89 ? 111 GLN A CG 1 ATOM 889 C CD . GLN A 1 111 ? 9.402 20.696 27.580 1.00 41.54 ? 111 GLN A CD 1 ATOM 890 O OE1 . GLN A 1 111 ? 8.586 20.387 26.706 1.00 44.91 ? 111 GLN A OE1 1 ATOM 891 N NE2 . GLN A 1 111 ? 10.720 20.692 27.364 1.00 34.23 ? 111 GLN A NE2 1 ATOM 892 N N . VAL A 1 112 ? 10.005 25.321 30.042 1.00 36.44 ? 112 VAL A N 1 ATOM 893 C CA . VAL A 1 112 ? 9.262 26.568 30.242 1.00 32.26 ? 112 VAL A CA 1 ATOM 894 C C . VAL A 1 112 ? 10.191 27.776 30.086 1.00 32.62 ? 112 VAL A C 1 ATOM 895 O O . VAL A 1 112 ? 11.238 27.855 30.731 1.00 35.81 ? 112 VAL A O 1 ATOM 896 C CB . VAL A 1 112 ? 8.556 26.599 31.614 1.00 31.05 ? 112 VAL A CB 1 ATOM 897 C CG1 . VAL A 1 112 ? 7.965 27.970 31.885 1.00 31.98 ? 112 VAL A CG1 1 ATOM 898 C CG2 . VAL A 1 112 ? 7.467 25.536 31.677 1.00 35.53 ? 112 VAL A CG2 1 ATOM 899 N N . TRP A 1 113 ? 9.799 28.705 29.219 1.00 29.62 ? 113 TRP A N 1 ATOM 900 C CA . TRP A 1 113 ? 10.599 29.887 28.928 1.00 30.80 ? 113 TRP A CA 1 ATOM 901 C C . TRP A 1 113 ? 9.832 31.145 29.304 1.00 33.04 ? 113 TRP A C 1 ATOM 902 O O . TRP A 1 113 ? 8.690 31.336 28.886 1.00 34.01 ? 113 TRP A O 1 ATOM 903 C CB . TRP A 1 113 ? 10.948 29.943 27.447 1.00 29.34 ? 113 TRP A CB 1 ATOM 904 C CG . TRP A 1 113 ? 11.744 28.784 26.927 1.00 31.01 ? 113 TRP A CG 1 ATOM 905 C CD1 . TRP A 1 113 ? 11.319 27.496 26.770 1.00 31.10 ? 113 TRP A CD1 1 ATOM 906 C CD2 . TRP A 1 113 ? 13.093 28.821 26.451 1.00 31.28 ? 113 TRP A CD2 1 ATOM 907 N NE1 . TRP A 1 113 ? 12.326 26.726 26.243 1.00 30.60 ? 113 TRP A NE1 1 ATOM 908 C CE2 . TRP A 1 113 ? 13.425 27.516 26.037 1.00 28.26 ? 113 TRP A CE2 1 ATOM 909 C CE3 . TRP A 1 113 ? 14.056 29.831 26.341 1.00 37.59 ? 113 TRP A CE3 1 ATOM 910 C CZ2 . TRP A 1 113 ? 14.680 27.192 25.523 1.00 33.84 ? 113 TRP A CZ2 1 ATOM 911 C CZ3 . TRP A 1 113 ? 15.303 29.509 25.831 1.00 38.31 ? 113 TRP A CZ3 1 ATOM 912 C CH2 . TRP A 1 113 ? 15.603 28.199 25.426 1.00 38.23 ? 113 TRP A CH2 1 ATOM 913 N N . ASN A 1 114 ? 10.468 32.006 30.088 1.00 34.91 ? 114 ASN A N 1 ATOM 914 C CA . ASN A 1 114 ? 9.830 33.219 30.574 1.00 30.92 ? 114 ASN A CA 1 ATOM 915 C C . ASN A 1 114 ? 10.265 34.443 29.775 1.00 36.61 ? 114 ASN A C 1 ATOM 916 O O . ASN A 1 114 ? 11.443 34.593 29.446 1.00 36.47 ? 114 ASN A O 1 ATOM 917 C CB . ASN A 1 114 ? 10.135 33.416 32.063 1.00 39.08 ? 114 ASN A CB 1 ATOM 918 C CG . ASN A 1 114 ? 9.337 32.472 32.970 1.00 42.62 ? 114 ASN A CG 1 ATOM 919 O OD1 . ASN A 1 114 ? 8.550 31.646 32.502 1.00 35.55 ? 114 ASN A OD1 1 ATOM 920 N ND2 . ASN A 1 114 ? 9.514 32.632 34.284 1.00 51.56 ? 114 ASN A ND2 1 ATOM 921 N N . GLY A 1 115 ? 9.307 35.308 29.455 1.00 37.46 ? 115 GLY A N 1 ATOM 922 C CA . GLY A 1 115 ? 9.588 36.556 28.740 1.00 32.37 ? 115 GLY A CA 1 ATOM 923 C C . GLY A 1 115 ? 8.527 37.602 29.015 1.00 29.14 ? 115 GLY A C 1 ATOM 924 O O . GLY A 1 115 ? 7.396 37.268 29.389 1.00 26.44 ? 115 GLY A O 1 ATOM 925 N N . SER A 1 116 ? 8.886 38.870 28.832 1.00 25.50 ? 116 SER A N 1 ATOM 926 C CA . SER A 1 116 ? 7.947 39.958 29.085 1.00 26.06 ? 116 SER A CA 1 ATOM 927 C C . SER A 1 116 ? 7.991 41.042 28.024 1.00 25.27 ? 116 SER A C 1 ATOM 928 O O . SER A 1 116 ? 9.052 41.350 27.475 1.00 27.35 ? 116 SER A O 1 ATOM 929 C CB . SER A 1 116 ? 8.204 40.581 30.451 1.00 32.07 ? 116 SER A CB 1 ATOM 930 O OG . SER A 1 116 ? 9.272 41.506 30.381 1.00 37.91 ? 116 SER A OG 1 ATOM 931 N N . VAL A 1 117 ? 6.825 41.627 27.764 1.00 26.97 ? 117 VAL A N 1 ATOM 932 C CA . VAL A 1 117 ? 6.677 42.684 26.764 1.00 25.26 ? 117 VAL A CA 1 ATOM 933 C C . VAL A 1 117 ? 5.824 43.819 27.326 1.00 25.01 ? 117 VAL A C 1 ATOM 934 O O . VAL A 1 117 ? 4.838 43.558 28.013 1.00 28.65 ? 117 VAL A O 1 ATOM 935 C CB . VAL A 1 117 ? 6.065 42.137 25.445 1.00 18.87 ? 117 VAL A CB 1 ATOM 936 C CG1 . VAL A 1 117 ? 4.582 41.797 25.607 1.00 16.75 ? 117 VAL A CG1 1 ATOM 937 C CG2 . VAL A 1 117 ? 6.275 43.110 24.308 1.00 19.45 ? 117 VAL A CG2 1 ATOM 938 N N . PRO A 1 118 ? 6.216 45.083 27.068 1.00 23.58 ? 118 PRO A N 1 ATOM 939 C CA . PRO A 1 118 ? 5.385 46.205 27.498 1.00 21.69 ? 118 PRO A CA 1 ATOM 940 C C . PRO A 1 118 ? 4.031 46.299 26.788 1.00 20.44 ? 118 PRO A C 1 ATOM 941 O O . PRO A 1 118 ? 3.868 45.805 25.670 1.00 21.08 ? 118 PRO A O 1 ATOM 942 C CB . PRO A 1 118 ? 6.252 47.428 27.175 1.00 19.14 ? 118 PRO A CB 1 ATOM 943 C CG . PRO A 1 118 ? 7.174 46.979 26.122 1.00 19.04 ? 118 PRO A CG 1 ATOM 944 C CD . PRO A 1 118 ? 7.455 45.545 26.415 1.00 24.85 ? 118 PRO A CD 1 ATOM 945 N N . GLU A 1 119 ? 3.076 46.923 27.470 1.00 19.47 ? 119 GLU A N 1 ATOM 946 C CA . GLU A 1 119 ? 1.767 47.264 26.930 1.00 20.52 ? 119 GLU A CA 1 ATOM 947 C C . GLU A 1 119 ? 1.826 48.034 25.621 1.00 19.57 ? 119 GLU A C 1 ATOM 948 O O . GLU A 1 119 ? 2.714 48.862 25.419 1.00 14.34 ? 119 GLU A O 1 ATOM 949 C CB . GLU A 1 119 ? 1.050 48.170 27.917 1.00 31.24 ? 119 GLU A CB 1 ATOM 950 C CG . GLU A 1 119 ? 0.254 47.487 28.985 1.00 29.67 ? 119 GLU A CG 1 ATOM 951 C CD . GLU A 1 119 ? -0.692 48.456 29.648 1.00 29.16 ? 119 GLU A CD 1 ATOM 952 O OE1 . GLU A 1 119 ? -0.227 49.517 30.127 1.00 28.31 ? 119 GLU A OE1 1 ATOM 953 O OE2 . GLU A 1 119 ? -1.907 48.168 29.674 1.00 33.09 ? 119 GLU A OE2 1 ATOM 954 N N . GLY A 1 120 ? 0.842 47.784 24.759 1.00 22.46 ? 120 GLY A N 1 ATOM 955 C CA . GLY A 1 120 ? 0.719 48.451 23.464 1.00 22.39 ? 120 GLY A CA 1 ATOM 956 C C . GLY A 1 120 ? 2.003 48.801 22.743 1.00 22.92 ? 120 GLY A C 1 ATOM 957 O O . GLY A 1 120 ? 2.203 49.945 22.348 1.00 30.62 ? 120 GLY A O 1 ATOM 958 N N . SER A 1 121 ? 2.893 47.825 22.607 1.00 25.08 ? 121 SER A N 1 ATOM 959 C CA . SER A 1 121 ? 4.113 48.011 21.840 1.00 26.68 ? 121 SER A CA 1 ATOM 960 C C . SER A 1 121 ? 3.794 47.844 20.372 1.00 28.09 ? 121 SER A C 1 ATOM 961 O O . SER A 1 121 ? 2.977 46.993 20.008 1.00 25.55 ? 121 SER A O 1 ATOM 962 C CB . SER A 1 121 ? 5.161 46.982 22.259 1.00 24.68 ? 121 SER A CB 1 ATOM 963 O OG . SER A 1 121 ? 5.173 46.785 23.658 1.00 17.90 ? 121 SER A OG 1 ATOM 964 N N . LYS A 1 122 ? 4.426 48.653 19.525 1.00 30.11 ? 122 LYS A N 1 ATOM 965 C CA . LYS A 1 122 ? 4.152 48.586 18.089 1.00 32.97 ? 122 LYS A CA 1 ATOM 966 C C . LYS A 1 122 ? 4.349 47.164 17.575 1.00 30.33 ? 122 LYS A C 1 ATOM 967 O O . LYS A 1 122 ? 5.296 46.489 17.978 1.00 33.48 ? 122 LYS A O 1 ATOM 968 C CB . LYS A 1 122 ? 4.994 49.595 17.287 1.00 33.73 ? 122 LYS A CB 1 ATOM 969 C CG . LYS A 1 122 ? 6.491 49.308 17.174 1.00 34.88 ? 122 LYS A CG 1 ATOM 970 C CD . LYS A 1 122 ? 7.141 50.319 16.235 1.00 41.28 ? 122 LYS A CD 1 ATOM 971 C CE . LYS A 1 122 ? 8.616 50.563 16.563 1.00 51.61 ? 122 LYS A CE 1 ATOM 972 N NZ . LYS A 1 122 ? 9.532 49.553 15.950 1.00 52.73 ? 122 LYS A NZ 1 ATOM 973 N N . PRO A 1 123 ? 3.429 46.691 16.720 1.00 30.39 ? 123 PRO A N 1 ATOM 974 C CA . PRO A 1 123 ? 3.638 45.416 16.048 1.00 33.79 ? 123 PRO A CA 1 ATOM 975 C C . PRO A 1 123 ? 5.034 45.376 15.426 1.00 33.60 ? 123 PRO A C 1 ATOM 976 O O . PRO A 1 123 ? 5.416 46.296 14.692 1.00 30.57 ? 123 PRO A O 1 ATOM 977 C CB . PRO A 1 123 ? 2.560 45.420 14.962 1.00 24.50 ? 123 PRO A CB 1 ATOM 978 C CG . PRO A 1 123 ? 1.469 46.218 15.555 1.00 25.34 ? 123 PRO A CG 1 ATOM 979 C CD . PRO A 1 123 ? 2.143 47.303 16.343 1.00 27.04 ? 123 PRO A CD 1 ATOM 980 N N . GLY A 1 124 ? 5.794 44.334 15.751 1.00 23.81 ? 124 GLY A N 1 ATOM 981 C CA . GLY A 1 124 ? 7.166 44.208 15.281 1.00 22.76 ? 124 GLY A CA 1 ATOM 982 C C . GLY A 1 124 ? 8.159 44.225 16.424 1.00 24.08 ? 124 GLY A C 1 ATOM 983 O O . GLY A 1 124 ? 9.361 44.055 16.213 1.00 23.72 ? 124 GLY A O 1 ATOM 984 N N . THR A 1 125 ? 7.650 44.419 17.636 1.00 22.26 ? 125 THR A N 1 ATOM 985 C CA . THR A 1 125 ? 8.481 44.491 18.832 1.00 20.01 ? 125 THR A CA 1 ATOM 986 C C . THR A 1 125 ? 8.987 43.106 19.230 1.00 26.37 ? 125 THR A C 1 ATOM 987 O O . THR A 1 125 ? 8.195 42.167 19.395 1.00 27.58 ? 125 THR A O 1 ATOM 988 C CB . THR A 1 125 ? 7.709 45.132 20.007 1.00 19.99 ? 125 THR A CB 1 ATOM 989 O OG1 . THR A 1 125 ? 7.302 46.457 19.645 1.00 26.37 ? 125 THR A OG1 1 ATOM 990 C CG2 . THR A 1 125 ? 8.570 45.200 21.256 1.00 20.98 ? 125 THR A CG2 1 ATOM 991 N N . TYR A 1 126 ? 10.310 42.989 19.366 1.00 25.30 ? 126 TYR A N 1 ATOM 992 C CA . TYR A 1 126 ? 10.939 41.761 19.851 1.00 24.33 ? 126 TYR A CA 1 ATOM 993 C C . TYR A 1 126 ? 10.539 41.514 21.303 1.00 23.61 ? 126 TYR A C 1 ATOM 994 O O . TYR A 1 126 ? 10.519 42.439 22.110 1.00 27.83 ? 126 TYR A O 1 ATOM 995 C CB . TYR A 1 126 ? 12.469 41.837 19.718 1.00 22.18 ? 126 TYR A CB 1 ATOM 996 C CG . TYR A 1 126 ? 13.205 40.749 20.476 1.00 28.82 ? 126 TYR A CG 1 ATOM 997 C CD1 . TYR A 1 126 ? 13.543 39.544 19.862 1.00 29.95 ? 126 TYR A CD1 1 ATOM 998 C CD2 . TYR A 1 126 ? 13.551 40.920 21.818 1.00 32.76 ? 126 TYR A CD2 1 ATOM 999 C CE1 . TYR A 1 126 ? 14.210 38.536 20.570 1.00 32.53 ? 126 TYR A CE1 1 ATOM 1000 C CE2 . TYR A 1 126 ? 14.212 39.922 22.530 1.00 27.72 ? 126 TYR A CE2 1 ATOM 1001 C CZ . TYR A 1 126 ? 14.541 38.739 21.904 1.00 27.96 ? 126 TYR A CZ 1 ATOM 1002 O OH . TYR A 1 126 ? 15.198 37.764 22.619 1.00 31.24 ? 126 TYR A OH 1 ATOM 1003 N N . VAL A 1 127 ? 10.225 40.265 21.628 1.00 20.17 ? 127 VAL A N 1 ATOM 1004 C CA . VAL A 1 127 ? 9.839 39.900 22.986 1.00 22.12 ? 127 VAL A CA 1 ATOM 1005 C C . VAL A 1 127 ? 10.912 39.043 23.659 1.00 26.77 ? 127 VAL A C 1 ATOM 1006 O O . VAL A 1 127 ? 11.515 39.453 24.651 1.00 29.05 ? 127 VAL A O 1 ATOM 1007 C CB . VAL A 1 127 ? 8.484 39.157 23.012 1.00 20.93 ? 127 VAL A CB 1 ATOM 1008 C CG1 . VAL A 1 127 ? 8.071 38.839 24.445 1.00 22.79 ? 127 VAL A CG1 1 ATOM 1009 C CG2 . VAL A 1 127 ? 7.416 39.975 22.309 1.00 20.24 ? 127 VAL A CG2 1 ATOM 1010 N N . MET A 1 128 ? 11.136 37.853 23.108 1.00 27.92 ? 128 MET A N 1 ATOM 1011 C CA . MET A 1 128 ? 12.045 36.867 23.685 1.00 27.62 ? 128 MET A CA 1 ATOM 1012 C C . MET A 1 128 ? 12.546 35.932 22.593 1.00 29.17 ? 128 MET A C 1 ATOM 1013 O O . MET A 1 128 ? 12.150 36.053 21.432 1.00 30.03 ? 128 MET A O 1 ATOM 1014 C CB . MET A 1 128 ? 11.330 36.061 24.770 1.00 21.47 ? 128 MET A CB 1 ATOM 1015 C CG . MET A 1 128 ? 10.254 35.137 24.238 1.00 18.88 ? 128 MET A CG 1 ATOM 1016 S SD . MET A 1 128 ? 9.194 34.493 25.538 1.00 30.18 ? 128 MET A SD 1 ATOM 1017 C CE . MET A 1 128 ? 10.325 33.432 26.431 1.00 35.42 ? 128 MET A CE 1 ATOM 1018 N N . THR A 1 129 ? 13.414 34.996 22.963 1.00 31.70 ? 129 THR A N 1 ATOM 1019 C CA . THR A 1 129 ? 13.905 34.009 22.008 1.00 32.30 ? 129 THR A CA 1 ATOM 1020 C C . THR A 1 129 ? 13.942 32.601 22.610 1.00 29.83 ? 129 THR A C 1 ATOM 1021 O O . THR A 1 129 ? 14.482 32.392 23.699 1.00 30.55 ? 129 THR A O 1 ATOM 1022 C CB . THR A 1 129 ? 15.273 34.426 21.386 1.00 29.17 ? 129 THR A CB 1 ATOM 1023 O OG1 . THR A 1 129 ? 15.685 33.450 20.425 1.00 35.98 ? 129 THR A OG1 1 ATOM 1024 C CG2 . THR A 1 129 ? 16.361 34.577 22.448 1.00 40.50 ? 129 THR A CG2 1 ATOM 1025 N N . VAL A 1 130 ? 13.334 31.649 21.905 1.00 23.12 ? 130 VAL A N 1 ATOM 1026 C CA . VAL A 1 130 ? 13.369 30.247 22.320 1.00 30.06 ? 130 VAL A CA 1 ATOM 1027 C C . VAL A 1 130 ? 14.041 29.377 21.259 1.00 36.92 ? 130 VAL A C 1 ATOM 1028 O O . VAL A 1 130 ? 13.695 29.434 20.080 1.00 38.54 ? 130 VAL A O 1 ATOM 1029 C CB . VAL A 1 130 ? 11.970 29.692 22.713 1.00 23.18 ? 130 VAL A CB 1 ATOM 1030 C CG1 . VAL A 1 130 ? 11.351 30.548 23.795 1.00 24.84 ? 130 VAL A CG1 1 ATOM 1031 C CG2 . VAL A 1 130 ? 11.045 29.609 21.521 1.00 22.68 ? 130 VAL A CG2 1 ATOM 1032 N N . THR A 1 131 ? 15.018 28.586 21.690 1.00 39.58 ? 131 THR A N 1 ATOM 1033 C CA . THR A 1 131 ? 15.793 27.762 20.771 1.00 36.92 ? 131 THR A CA 1 ATOM 1034 C C . THR A 1 131 ? 15.858 26.314 21.223 1.00 37.40 ? 131 THR A C 1 ATOM 1035 O O . THR A 1 131 ? 15.913 26.023 22.421 1.00 39.75 ? 131 THR A O 1 ATOM 1036 C CB . THR A 1 131 ? 17.218 28.312 20.582 1.00 43.45 ? 131 THR A CB 1 ATOM 1037 O OG1 . THR A 1 131 ? 17.672 28.888 21.818 1.00 52.77 ? 131 THR A OG1 1 ATOM 1038 C CG2 . THR A 1 131 ? 17.224 29.377 19.478 1.00 43.98 ? 131 THR A CG2 1 ATOM 1039 N N . ALA A 1 132 ? 15.834 25.414 20.247 1.00 36.56 ? 132 ALA A N 1 ATOM 1040 C CA . ALA A 1 132 ? 15.967 23.990 20.496 1.00 31.60 ? 132 ALA A CA 1 ATOM 1041 C C . ALA A 1 132 ? 17.281 23.493 19.920 1.00 30.26 ? 132 ALA A C 1 ATOM 1042 O O . ALA A 1 132 ? 17.926 24.184 19.127 1.00 27.45 ? 132 ALA A O 1 ATOM 1043 C CB . ALA A 1 132 ? 14.808 23.239 19.881 1.00 27.73 ? 132 ALA A CB 1 ATOM 1044 N N . ILE A 1 133 ? 17.679 22.295 20.329 1.00 29.88 ? 133 ILE A N 1 ATOM 1045 C CA . ILE A 1 133 ? 18.863 21.652 19.770 1.00 30.44 ? 133 ILE A CA 1 ATOM 1046 C C . ILE A 1 133 ? 18.511 20.267 19.256 1.00 27.89 ? 133 ILE A C 1 ATOM 1047 O O . ILE A 1 133 ? 17.552 19.651 19.725 1.00 28.93 ? 133 ILE A O 1 ATOM 1048 C CB . ILE A 1 133 ? 20.032 21.580 20.781 1.00 24.21 ? 133 ILE A CB 1 ATOM 1049 C CG1 . ILE A 1 133 ? 19.553 21.036 22.133 1.00 24.61 ? 133 ILE A CG1 1 ATOM 1050 C CG2 . ILE A 1 133 ? 20.697 22.952 20.923 1.00 26.49 ? 133 ILE A CG2 1 ATOM 1051 C CD1 . ILE A 1 133 ? 20.664 20.794 23.141 1.00 31.58 ? 133 ILE A CD1 1 ATOM 1052 N N . ASP A 1 134 ? 19.281 19.797 18.278 1.00 26.56 ? 134 ASP A N 1 ATOM 1053 C CA . ASP A 1 134 ? 19.070 18.483 17.683 1.00 27.91 ? 134 ASP A CA 1 ATOM 1054 C C . ASP A 1 134 ? 20.333 17.634 17.804 1.00 30.22 ? 134 ASP A C 1 ATOM 1055 O O . ASP A 1 134 ? 21.397 18.002 17.293 1.00 28.12 ? 134 ASP A O 1 ATOM 1056 C CB . ASP A 1 134 ? 18.660 18.625 16.215 1.00 23.77 ? 134 ASP A CB 1 ATOM 1057 C CG . ASP A 1 134 ? 18.035 17.364 15.655 1.00 24.28 ? 134 ASP A CG 1 ATOM 1058 O OD1 . ASP A 1 134 ? 16.969 17.460 15.017 1.00 23.75 ? 134 ASP A OD1 1 ATOM 1059 O OD2 . ASP A 1 134 ? 18.597 16.268 15.839 1.00 27.39 ? 134 ASP A OD2 1 ATOM 1060 N N . ALA A 1 135 ? 20.204 16.493 18.476 1.00 27.30 ? 135 ALA A N 1 ATOM 1061 C CA . ALA A 1 135 ? 21.328 15.580 18.688 1.00 29.39 ? 135 ALA A CA 1 ATOM 1062 C C . ALA A 1 135 ? 21.937 15.021 17.392 1.00 27.54 ? 135 ALA A C 1 ATOM 1063 O O . ALA A 1 135 ? 23.065 14.521 17.405 1.00 30.55 ? 135 ALA A O 1 ATOM 1064 C CB . ALA A 1 135 ? 20.919 14.451 19.619 1.00 33.25 ? 135 ALA A CB 1 ATOM 1065 N N . ASP A 1 136 ? 21.196 15.116 16.287 1.00 24.47 ? 136 ASP A N 1 ATOM 1066 C CA . ASP A 1 136 ? 21.680 14.690 14.971 1.00 21.59 ? 136 ASP A CA 1 ATOM 1067 C C . ASP A 1 136 ? 22.727 15.659 14.426 1.00 24.47 ? 136 ASP A C 1 ATOM 1068 O O . ASP A 1 136 ? 23.134 16.590 15.122 1.00 27.52 ? 136 ASP A O 1 ATOM 1069 C CB . ASP A 1 136 ? 20.515 14.550 13.989 1.00 23.18 ? 136 ASP A CB 1 ATOM 1070 C CG . ASP A 1 136 ? 19.516 13.486 14.410 1.00 27.92 ? 136 ASP A CG 1 ATOM 1071 O OD1 . ASP A 1 136 ? 19.931 12.343 14.691 1.00 27.71 ? 136 ASP A OD1 1 ATOM 1072 O OD2 . ASP A 1 136 ? 18.305 13.786 14.446 1.00 29.46 ? 136 ASP A OD2 1 ATOM 1073 N N . ASP A 1 137 ? 23.165 15.433 13.188 1.00 25.39 ? 137 ASP A N 1 ATOM 1074 C CA . ASP A 1 137 ? 24.181 16.279 12.553 1.00 33.23 ? 137 ASP A CA 1 ATOM 1075 C C . ASP A 1 137 ? 23.614 17.648 12.166 1.00 34.73 ? 137 ASP A C 1 ATOM 1076 O O . ASP A 1 137 ? 22.661 17.727 11.388 1.00 38.29 ? 137 ASP A O 1 ATOM 1077 C CB . ASP A 1 137 ? 24.787 15.582 11.322 1.00 33.49 ? 137 ASP A CB 1 ATOM 1078 C CG . ASP A 1 137 ? 25.972 16.354 10.716 1.00 47.90 ? 137 ASP A CG 1 ATOM 1079 O OD1 . ASP A 1 137 ? 26.434 17.360 11.303 1.00 44.65 ? 137 ASP A OD1 1 ATOM 1080 O OD2 . ASP A 1 137 ? 26.454 15.943 9.638 1.00 48.99 ? 137 ASP A OD2 1 ATOM 1081 N N . PRO A 1 138 ? 24.196 18.733 12.713 1.00 34.03 ? 138 PRO A N 1 ATOM 1082 C CA . PRO A 1 138 ? 23.780 20.072 12.311 1.00 37.23 ? 138 PRO A CA 1 ATOM 1083 C C . PRO A 1 138 ? 24.039 20.334 10.828 1.00 36.92 ? 138 PRO A C 1 ATOM 1084 O O . PRO A 1 138 ? 23.251 21.023 10.182 1.00 42.02 ? 138 PRO A O 1 ATOM 1085 C CB . PRO A 1 138 ? 24.658 20.985 13.174 1.00 40.48 ? 138 PRO A CB 1 ATOM 1086 C CG . PRO A 1 138 ? 25.068 20.139 14.329 1.00 42.43 ? 138 PRO A CG 1 ATOM 1087 C CD . PRO A 1 138 ? 25.247 18.779 13.743 1.00 37.98 ? 138 PRO A CD 1 ATOM 1088 N N . ASN A 1 139 ? 25.121 19.772 10.295 1.00 36.73 ? 139 ASN A N 1 ATOM 1089 C CA . ASN A 1 139 ? 25.486 19.967 8.890 1.00 40.55 ? 139 ASN A CA 1 ATOM 1090 C C . ASN A 1 139 ? 24.587 19.242 7.887 1.00 41.95 ? 139 ASN A C 1 ATOM 1091 O O . ASN A 1 139 ? 24.704 19.440 6.675 1.00 38.49 ? 139 ASN A O 1 ATOM 1092 C CB . ASN A 1 139 ? 26.958 19.609 8.661 1.00 45.66 ? 139 ASN A CB 1 ATOM 1093 C CG . ASN A 1 139 ? 27.900 20.730 9.073 1.00 52.43 ? 139 ASN A CG 1 ATOM 1094 O OD1 . ASN A 1 139 ? 27.662 21.902 8.763 1.00 50.67 ? 139 ASN A OD1 1 ATOM 1095 N ND2 . ASN A 1 139 ? 28.977 20.375 9.775 1.00 53.02 ? 139 ASN A ND2 1 ATOM 1096 N N . ALA A 1 140 ? 23.692 18.405 8.400 1.00 39.69 ? 140 ALA A N 1 ATOM 1097 C CA . ALA A 1 140 ? 22.742 17.684 7.566 1.00 39.56 ? 140 ALA A CA 1 ATOM 1098 C C . ALA A 1 140 ? 21.320 18.146 7.864 1.00 38.10 ? 140 ALA A C 1 ATOM 1099 O O . ALA A 1 140 ? 21.055 18.715 8.927 1.00 36.11 ? 140 ALA A O 1 ATOM 1100 C CB . ALA A 1 140 ? 22.877 16.184 7.792 1.00 40.05 ? 140 ALA A CB 1 ATOM 1101 N N . LEU A 1 141 ? 20.413 17.893 6.921 1.00 41.87 ? 141 LEU A N 1 ATOM 1102 C CA . LEU A 1 141 ? 18.997 18.239 7.061 1.00 35.98 ? 141 LEU A CA 1 ATOM 1103 C C . LEU A 1 141 ? 18.406 17.743 8.372 1.00 29.90 ? 141 LEU A C 1 ATOM 1104 O O . LEU A 1 141 ? 17.546 18.397 8.947 1.00 30.50 ? 141 LEU A O 1 ATOM 1105 C CB . LEU A 1 141 ? 18.186 17.678 5.887 1.00 34.56 ? 141 LEU A CB 1 ATOM 1106 C CG . LEU A 1 141 ? 17.858 18.578 4.687 1.00 39.00 ? 141 LEU A CG 1 ATOM 1107 C CD1 . LEU A 1 141 ? 19.103 19.040 3.923 1.00 39.44 ? 141 LEU A CD1 1 ATOM 1108 C CD2 . LEU A 1 141 ? 16.892 17.853 3.751 1.00 38.10 ? 141 LEU A CD2 1 ATOM 1109 N N . ASN A 1 142 ? 18.892 16.596 8.839 1.00 31.16 ? 142 ASN A N 1 ATOM 1110 C CA . ASN A 1 142 ? 18.398 15.946 10.058 1.00 31.63 ? 142 ASN A CA 1 ATOM 1111 C C . ASN A 1 142 ? 18.430 16.833 11.303 1.00 29.20 ? 142 ASN A C 1 ATOM 1112 O O . ASN A 1 142 ? 17.559 16.730 12.172 1.00 29.90 ? 142 ASN A O 1 ATOM 1113 C CB . ASN A 1 142 ? 19.183 14.655 10.336 1.00 31.59 ? 142 ASN A CB 1 ATOM 1114 C CG . ASN A 1 142 ? 19.233 13.713 9.134 1.00 31.25 ? 142 ASN A CG 1 ATOM 1115 O OD1 . ASN A 1 142 ? 18.329 13.690 8.299 1.00 33.16 ? 142 ASN A OD1 1 ATOM 1116 N ND2 . ASN A 1 142 ? 20.296 12.921 9.055 1.00 32.84 ? 142 ASN A ND2 1 ATOM 1117 N N . GLY A 1 143 ? 19.434 17.698 11.386 1.00 25.96 ? 143 GLY A N 1 ATOM 1118 C CA . GLY A 1 143 ? 19.608 18.540 12.559 1.00 29.88 ? 143 GLY A CA 1 ATOM 1119 C C . GLY A 1 143 ? 19.321 20.007 12.323 1.00 30.32 ? 143 GLY A C 1 ATOM 1120 O O . GLY A 1 143 ? 19.716 20.855 13.129 1.00 33.01 ? 143 GLY A O 1 ATOM 1121 N N . MET A 1 144 ? 18.637 20.310 11.222 1.00 28.25 ? 144 MET A N 1 ATOM 1122 C CA . MET A 1 144 ? 18.295 21.690 10.883 1.00 26.76 ? 144 MET A CA 1 ATOM 1123 C C . MET A 1 144 ? 16.856 22.013 11.276 1.00 27.04 ? 144 MET A C 1 ATOM 1124 O O . MET A 1 144 ? 15.907 21.431 10.741 1.00 25.97 ? 144 MET A O 1 ATOM 1125 C CB . MET A 1 144 ? 18.560 21.962 9.402 1.00 26.93 ? 144 MET A CB 1 ATOM 1126 C CG . MET A 1 144 ? 20.039 21.850 9.040 1.00 29.71 ? 144 MET A CG 1 ATOM 1127 S SD . MET A 1 144 ? 20.444 22.271 7.337 1.00 34.63 ? 144 MET A SD 1 ATOM 1128 C CE . MET A 1 144 ? 20.239 24.056 7.364 1.00 44.47 ? 144 MET A CE 1 ATOM 1129 N N . LEU A 1 145 ? 16.716 22.952 12.211 1.00 25.39 ? 145 LEU A N 1 ATOM 1130 C CA . LEU A 1 145 ? 15.450 23.213 12.905 1.00 26.16 ? 145 LEU A CA 1 ATOM 1131 C C . LEU A 1 145 ? 14.631 24.400 12.384 1.00 28.39 ? 145 LEU A C 1 ATOM 1132 O O . LEU A 1 145 ? 15.189 25.415 11.960 1.00 25.62 ? 145 LEU A O 1 ATOM 1133 C CB . LEU A 1 145 ? 15.727 23.421 14.392 1.00 21.38 ? 145 LEU A CB 1 ATOM 1134 C CG . LEU A 1 145 ? 15.650 22.244 15.361 1.00 21.25 ? 145 LEU A CG 1 ATOM 1135 C CD1 . LEU A 1 145 ? 16.074 20.946 14.719 1.00 28.01 ? 145 LEU A CD1 1 ATOM 1136 C CD2 . LEU A 1 145 ? 16.503 22.537 16.576 1.00 22.65 ? 145 LEU A CD2 1 ATOM 1137 N N . ARG A 1 146 ? 13.306 24.256 12.430 1.00 24.73 ? 146 ARG A N 1 ATOM 1138 C CA . ARG A 1 146 ? 12.387 25.360 12.169 1.00 22.73 ? 146 ARG A CA 1 ATOM 1139 C C . ARG A 1 146 ? 11.339 25.485 13.263 1.00 28.83 ? 146 ARG A C 1 ATOM 1140 O O . ARG A 1 146 ? 10.901 24.485 13.840 1.00 32.39 ? 146 ARG A O 1 ATOM 1141 C CB . ARG A 1 146 ? 11.700 25.215 10.814 1.00 22.94 ? 146 ARG A CB 1 ATOM 1142 C CG . ARG A 1 146 ? 12.628 25.331 9.618 1.00 28.22 ? 146 ARG A CG 1 ATOM 1143 C CD . ARG A 1 146 ? 13.381 26.644 9.588 1.00 29.41 ? 146 ARG A CD 1 ATOM 1144 N NE . ARG A 1 146 ? 14.780 26.410 9.243 1.00 32.65 ? 146 ARG A NE 1 ATOM 1145 C CZ . ARG A 1 146 ? 15.316 26.635 8.047 1.00 34.95 ? 146 ARG A CZ 1 ATOM 1146 N NH1 . ARG A 1 146 ? 14.577 27.130 7.057 1.00 30.57 ? 146 ARG A NH1 1 ATOM 1147 N NH2 . ARG A 1 146 ? 16.604 26.373 7.847 1.00 37.94 ? 146 ARG A NH2 1 ATOM 1148 N N . TYR A 1 147 ? 10.930 26.722 13.527 1.00 27.49 ? 147 TYR A N 1 ATOM 1149 C CA . TYR A 1 147 ? 10.003 27.020 14.612 1.00 24.67 ? 147 TYR A CA 1 ATOM 1150 C C . TYR A 1 147 ? 8.651 27.538 14.126 1.00 25.13 ? 147 TYR A C 1 ATOM 1151 O O . TYR A 1 147 ? 8.531 28.063 13.015 1.00 26.43 ? 147 TYR A O 1 ATOM 1152 C CB . TYR A 1 147 ? 10.625 28.042 15.552 1.00 24.33 ? 147 TYR A CB 1 ATOM 1153 C CG . TYR A 1 147 ? 11.959 27.638 16.120 1.00 22.64 ? 147 TYR A CG 1 ATOM 1154 C CD1 . TYR A 1 147 ? 13.143 28.031 15.507 1.00 27.02 ? 147 TYR A CD1 1 ATOM 1155 C CD2 . TYR A 1 147 ? 12.040 26.880 17.284 1.00 23.43 ? 147 TYR A CD2 1 ATOM 1156 C CE1 . TYR A 1 147 ? 14.378 27.668 16.033 1.00 31.73 ? 147 TYR A CE1 1 ATOM 1157 C CE2 . TYR A 1 147 ? 13.269 26.514 17.819 1.00 26.80 ? 147 TYR A CE2 1 ATOM 1158 C CZ . TYR A 1 147 ? 14.433 26.911 17.189 1.00 27.62 ? 147 TYR A CZ 1 ATOM 1159 O OH . TYR A 1 147 ? 15.653 26.555 17.709 1.00 29.30 ? 147 TYR A OH 1 ATOM 1160 N N . ARG A 1 148 ? 7.639 27.379 14.975 1.00 18.48 ? 148 ARG A N 1 ATOM 1161 C CA . ARG A 1 148 ? 6.304 27.910 14.730 1.00 19.34 ? 148 ARG A CA 1 ATOM 1162 C C . ARG A 1 148 ? 5.515 27.910 16.033 1.00 22.70 ? 148 ARG A C 1 ATOM 1163 O O . ARG A 1 148 ? 5.900 27.243 16.992 1.00 23.40 ? 148 ARG A O 1 ATOM 1164 C CB . ARG A 1 148 ? 5.582 27.104 13.644 1.00 19.39 ? 148 ARG A CB 1 ATOM 1165 C CG . ARG A 1 148 ? 5.277 25.671 14.021 1.00 26.79 ? 148 ARG A CG 1 ATOM 1166 C CD . ARG A 1 148 ? 5.580 24.724 12.876 1.00 36.87 ? 148 ARG A CD 1 ATOM 1167 N NE . ARG A 1 148 ? 4.454 24.541 11.963 1.00 40.30 ? 148 ARG A NE 1 ATOM 1168 C CZ . ARG A 1 148 ? 3.605 23.517 12.010 1.00 40.32 ? 148 ARG A CZ 1 ATOM 1169 N NH1 . ARG A 1 148 ? 3.734 22.573 12.936 1.00 35.11 ? 148 ARG A NH1 1 ATOM 1170 N NH2 . ARG A 1 148 ? 2.622 23.435 11.126 1.00 43.65 ? 148 ARG A NH2 1 ATOM 1171 N N . ILE A 1 149 ? 4.418 28.662 16.067 1.00 22.08 ? 149 ILE A N 1 ATOM 1172 C CA . ILE A 1 149 ? 3.539 28.686 17.236 1.00 19.63 ? 149 ILE A CA 1 ATOM 1173 C C . ILE A 1 149 ? 2.320 27.802 17.002 1.00 20.91 ? 149 ILE A C 1 ATOM 1174 O O . ILE A 1 149 ? 1.691 27.861 15.950 1.00 23.42 ? 149 ILE A O 1 ATOM 1175 C CB . ILE A 1 149 ? 3.101 30.119 17.602 1.00 18.05 ? 149 ILE A CB 1 ATOM 1176 C CG1 . ILE A 1 149 ? 4.309 30.941 18.055 1.00 18.70 ? 149 ILE A CG1 1 ATOM 1177 C CG2 . ILE A 1 149 ? 2.065 30.095 18.708 1.00 23.12 ? 149 ILE A CG2 1 ATOM 1178 C CD1 . ILE A 1 149 ? 4.074 32.437 18.075 1.00 14.84 ? 149 ILE A CD1 1 ATOM 1179 N N . LEU A 1 150 ? 2.001 26.982 17.998 1.00 23.32 ? 150 LEU A N 1 ATOM 1180 C CA . LEU A 1 150 ? 0.894 26.043 17.905 1.00 24.80 ? 150 LEU A CA 1 ATOM 1181 C C . LEU A 1 150 ? -0.382 26.526 18.576 1.00 27.06 ? 150 LEU A C 1 ATOM 1182 O O . LEU A 1 150 ? -1.481 26.202 18.121 1.00 29.68 ? 150 LEU A O 1 ATOM 1183 C CB . LEU A 1 150 ? 1.296 24.696 18.491 1.00 23.27 ? 150 LEU A CB 1 ATOM 1184 C CG . LEU A 1 150 ? 2.020 23.749 17.542 1.00 28.22 ? 150 LEU A CG 1 ATOM 1185 C CD1 . LEU A 1 150 ? 2.513 22.555 18.328 1.00 35.17 ? 150 LEU A CD1 1 ATOM 1186 C CD2 . LEU A 1 150 ? 1.116 23.306 16.392 1.00 27.47 ? 150 LEU A CD2 1 ATOM 1187 N N . SER A 1 151 ? -0.243 27.275 19.666 1.00 21.70 ? 151 SER A N 1 ATOM 1188 C CA . SER A 1 151 ? -1.409 27.820 20.349 1.00 22.24 ? 151 SER A CA 1 ATOM 1189 C C . SER A 1 151 ? -1.061 28.997 21.243 1.00 27.97 ? 151 SER A C 1 ATOM 1190 O O . SER A 1 151 ? 0.073 29.121 21.726 1.00 27.75 ? 151 SER A O 1 ATOM 1191 C CB . SER A 1 151 ? -2.120 26.740 21.167 1.00 27.32 ? 151 SER A CB 1 ATOM 1192 O OG . SER A 1 151 ? -1.274 26.238 22.186 1.00 30.48 ? 151 SER A OG 1 ATOM 1193 N N . GLN A 1 152 ? -2.061 29.852 21.451 1.00 28.51 ? 152 GLN A N 1 ATOM 1194 C CA . GLN A 1 152 ? -1.965 31.005 22.337 1.00 26.00 ? 152 GLN A CA 1 ATOM 1195 C C . GLN A 1 152 ? -3.144 30.974 23.301 1.00 28.05 ? 152 GLN A C 1 ATOM 1196 O O . GLN A 1 152 ? -4.285 30.741 22.891 1.00 31.16 ? 152 GLN A O 1 ATOM 1197 C CB . GLN A 1 152 ? -1.986 32.293 21.514 1.00 24.10 ? 152 GLN A CB 1 ATOM 1198 C CG . GLN A 1 152 ? -1.923 33.586 22.315 1.00 23.94 ? 152 GLN A CG 1 ATOM 1199 C CD . GLN A 1 152 ? -2.002 34.810 21.421 1.00 28.81 ? 152 GLN A CD 1 ATOM 1200 O OE1 . GLN A 1 152 ? -1.012 35.209 20.797 1.00 27.06 ? 152 GLN A OE1 1 ATOM 1201 N NE2 . GLN A 1 152 ? -3.189 35.407 21.344 1.00 27.46 ? 152 GLN A NE2 1 ATOM 1202 N N . ALA A 1 153 ? -2.861 31.195 24.581 1.00 26.44 ? 153 ALA A N 1 ATOM 1203 C CA . ALA A 1 153 ? -3.902 31.308 25.595 1.00 23.61 ? 153 ALA A CA 1 ATOM 1204 C C . ALA A 1 153 ? -3.669 32.549 26.458 1.00 27.65 ? 153 ALA A C 1 ATOM 1205 O O . ALA A 1 153 ? -2.573 32.732 27.006 1.00 30.86 ? 153 ALA A O 1 ATOM 1206 C CB . ALA A 1 153 ? -3.950 30.060 26.448 1.00 29.34 ? 153 ALA A CB 1 ATOM 1207 N N . PRO A 1 154 ? -4.689 33.422 26.564 1.00 24.16 ? 154 PRO A N 1 ATOM 1208 C CA . PRO A 1 154 ? -5.987 33.294 25.904 1.00 24.45 ? 154 PRO A CA 1 ATOM 1209 C C . PRO A 1 154 ? -5.984 33.880 24.485 1.00 27.07 ? 154 PRO A C 1 ATOM 1210 O O . PRO A 1 154 ? -4.964 34.415 24.038 1.00 27.59 ? 154 PRO A O 1 ATOM 1211 C CB . PRO A 1 154 ? -6.914 34.085 26.823 1.00 27.89 ? 154 PRO A CB 1 ATOM 1212 C CG . PRO A 1 154 ? -6.034 35.134 27.437 1.00 28.55 ? 154 PRO A CG 1 ATOM 1213 C CD . PRO A 1 154 ? -4.608 34.647 27.380 1.00 25.29 ? 154 PRO A CD 1 ATOM 1214 N N . SER A 1 155 ? -7.119 33.783 23.796 1.00 21.88 ? 155 SER A N 1 ATOM 1215 C CA . SER A 1 155 ? -7.203 34.138 22.376 1.00 23.84 ? 155 SER A CA 1 ATOM 1216 C C . SER A 1 155 ? -7.556 35.603 22.089 1.00 25.75 ? 155 SER A C 1 ATOM 1217 O O . SER A 1 155 ? -7.832 35.967 20.944 1.00 26.24 ? 155 SER A O 1 ATOM 1218 C CB . SER A 1 155 ? -8.207 33.217 21.676 1.00 26.73 ? 155 SER A CB 1 ATOM 1219 O OG . SER A 1 155 ? -9.498 33.334 22.250 1.00 25.11 ? 155 SER A OG 1 ATOM 1220 N N . THR A 1 156 ? -7.541 36.439 23.120 1.00 23.16 ? 156 THR A N 1 ATOM 1221 C CA . THR A 1 156 ? -7.979 37.827 22.991 1.00 22.95 ? 156 THR A CA 1 ATOM 1222 C C . THR A 1 156 ? -6.821 38.801 23.235 1.00 24.85 ? 156 THR A C 1 ATOM 1223 O O . THR A 1 156 ? -5.896 38.473 23.973 1.00 27.26 ? 156 THR A O 1 ATOM 1224 C CB . THR A 1 156 ? -9.121 38.127 23.972 1.00 27.63 ? 156 THR A CB 1 ATOM 1225 O OG1 . THR A 1 156 ? -8.664 37.924 25.315 1.00 30.13 ? 156 THR A OG1 1 ATOM 1226 C CG2 . THR A 1 156 ? -10.318 37.218 23.698 1.00 26.59 ? 156 THR A CG2 1 ATOM 1227 N N . PRO A 1 157 ? -6.858 40.001 22.616 1.00 28.06 ? 157 PRO A N 1 ATOM 1228 C CA . PRO A 1 157 ? -7.859 40.548 21.693 1.00 28.62 ? 157 PRO A CA 1 ATOM 1229 C C . PRO A 1 157 ? -7.790 39.918 20.308 1.00 32.31 ? 157 PRO A C 1 ATOM 1230 O O . PRO A 1 157 ? -8.789 39.905 19.588 1.00 37.32 ? 157 PRO A O 1 ATOM 1231 C CB . PRO A 1 157 ? -7.477 42.024 21.607 1.00 26.60 ? 157 PRO A CB 1 ATOM 1232 C CG . PRO A 1 157 ? -6.016 42.040 21.851 1.00 25.31 ? 157 PRO A CG 1 ATOM 1233 C CD . PRO A 1 157 ? -5.769 40.965 22.862 1.00 26.22 ? 157 PRO A CD 1 ATOM 1234 N N . SER A 1 158 ? -6.615 39.415 19.940 1.00 27.99 ? 158 SER A N 1 ATOM 1235 C CA . SER A 1 158 ? -6.452 38.666 18.706 1.00 22.79 ? 158 SER A CA 1 ATOM 1236 C C . SER A 1 158 ? -5.898 37.284 19.020 1.00 25.34 ? 158 SER A C 1 ATOM 1237 O O . SER A 1 158 ? -5.069 37.150 19.922 1.00 28.88 ? 158 SER A O 1 ATOM 1238 C CB . SER A 1 158 ? -5.516 39.406 17.759 1.00 24.31 ? 158 SER A CB 1 ATOM 1239 O OG . SER A 1 158 ? -5.129 38.569 16.685 1.00 29.95 ? 158 SER A OG 1 ATOM 1240 N N . PRO A 1 159 ? -6.365 36.245 18.290 1.00 27.79 ? 159 PRO A N 1 ATOM 1241 C CA . PRO A 1 159 ? -5.832 34.883 18.427 1.00 27.84 ? 159 PRO A CA 1 ATOM 1242 C C . PRO A 1 159 ? -4.321 34.808 18.241 1.00 30.38 ? 159 PRO A C 1 ATOM 1243 O O . PRO A 1 159 ? -3.668 34.004 18.906 1.00 30.78 ? 159 PRO A O 1 ATOM 1244 C CB . PRO A 1 159 ? -6.520 34.120 17.292 1.00 23.41 ? 159 PRO A CB 1 ATOM 1245 C CG . PRO A 1 159 ? -7.769 34.851 17.054 1.00 24.44 ? 159 PRO A CG 1 ATOM 1246 C CD . PRO A 1 159 ? -7.458 36.298 17.304 1.00 29.87 ? 159 PRO A CD 1 ATOM 1247 N N . ASN A 1 160 ? -3.784 35.651 17.356 1.00 28.59 ? 160 ASN A N 1 ATOM 1248 C CA . ASN A 1 160 ? -2.377 35.604 16.967 1.00 24.95 ? 160 ASN A CA 1 ATOM 1249 C C . ASN A 1 160 ? -1.612 36.870 17.288 1.00 20.07 ? 160 ASN A C 1 ATOM 1250 O O . ASN A 1 160 ? -1.192 37.592 16.390 1.00 18.40 ? 160 ASN A O 1 ATOM 1251 C CB . ASN A 1 160 ? -2.264 35.309 15.476 1.00 22.32 ? 160 ASN A CB 1 ATOM 1252 C CG . ASN A 1 160 ? -2.705 33.919 15.137 1.00 24.33 ? 160 ASN A CG 1 ATOM 1253 O OD1 . ASN A 1 160 ? -2.010 32.951 15.442 1.00 29.24 ? 160 ASN A OD1 1 ATOM 1254 N ND2 . ASN A 1 160 ? -3.870 33.802 14.510 1.00 22.87 ? 160 ASN A ND2 1 ATOM 1255 N N . MET A 1 161 ? -1.418 37.125 18.574 1.00 18.78 ? 161 MET A N 1 ATOM 1256 C CA . MET A 1 161 ? -0.700 38.316 19.012 1.00 21.56 ? 161 MET A CA 1 ATOM 1257 C C . MET A 1 161 ? 0.772 38.269 18.624 1.00 21.94 ? 161 MET A C 1 ATOM 1258 O O . MET A 1 161 ? 1.382 39.299 18.332 1.00 20.63 ? 161 MET A O 1 ATOM 1259 C CB . MET A 1 161 ? -0.835 38.497 20.524 1.00 22.72 ? 161 MET A CB 1 ATOM 1260 C CG . MET A 1 161 ? -2.275 38.567 21.018 1.00 26.74 ? 161 MET A CG 1 ATOM 1261 S SD . MET A 1 161 ? -3.227 39.924 20.304 1.00 28.80 ? 161 MET A SD 1 ATOM 1262 C CE . MET A 1 161 ? -2.237 41.329 20.839 1.00 23.86 ? 161 MET A CE 1 ATOM 1263 N N . PHE A 1 162 ? 1.335 37.067 18.614 1.00 22.06 ? 162 PHE A N 1 ATOM 1264 C CA . PHE A 1 162 ? 2.757 36.906 18.369 1.00 21.41 ? 162 PHE A CA 1 ATOM 1265 C C . PHE A 1 162 ? 3.005 36.075 17.128 1.00 21.11 ? 162 PHE A C 1 ATOM 1266 O O . PHE A 1 162 ? 2.107 35.394 16.635 1.00 26.04 ? 162 PHE A O 1 ATOM 1267 C CB . PHE A 1 162 ? 3.426 36.237 19.569 1.00 21.87 ? 162 PHE A CB 1 ATOM 1268 C CG . PHE A 1 162 ? 3.054 36.838 20.895 1.00 19.28 ? 162 PHE A CG 1 ATOM 1269 C CD1 . PHE A 1 162 ? 1.979 36.338 21.622 1.00 17.87 ? 162 PHE A CD1 1 ATOM 1270 C CD2 . PHE A 1 162 ? 3.788 37.893 21.424 1.00 17.13 ? 162 PHE A CD2 1 ATOM 1271 C CE1 . PHE A 1 162 ? 1.635 36.884 22.849 1.00 19.47 ? 162 PHE A CE1 1 ATOM 1272 C CE2 . PHE A 1 162 ? 3.453 38.445 22.653 1.00 18.12 ? 162 PHE A CE2 1 ATOM 1273 C CZ . PHE A 1 162 ? 2.372 37.940 23.367 1.00 18.58 ? 162 PHE A CZ 1 ATOM 1274 N N . THR A 1 163 ? 4.226 36.154 16.616 1.00 17.65 ? 163 THR A N 1 ATOM 1275 C CA . THR A 1 163 ? 4.709 35.198 15.637 1.00 17.81 ? 163 THR A CA 1 ATOM 1276 C C . THR A 1 163 ? 6.103 34.746 16.079 1.00 20.49 ? 163 THR A C 1 ATOM 1277 O O . THR A 1 163 ? 6.519 35.053 17.197 1.00 23.74 ? 163 THR A O 1 ATOM 1278 C CB . THR A 1 163 ? 4.689 35.774 14.203 1.00 18.43 ? 163 THR A CB 1 ATOM 1279 O OG1 . THR A 1 163 ? 4.727 34.696 13.255 1.00 18.62 ? 163 THR A OG1 1 ATOM 1280 C CG2 . THR A 1 163 ? 5.858 36.738 13.963 1.00 16.66 ? 163 THR A CG2 1 ATOM 1281 N N . ILE A 1 164 ? 6.812 34.008 15.229 1.00 20.81 ? 164 ILE A N 1 ATOM 1282 C CA . ILE A 1 164 ? 8.173 33.571 15.541 1.00 18.26 ? 164 ILE A CA 1 ATOM 1283 C C . ILE A 1 164 ? 8.978 33.414 14.264 1.00 19.45 ? 164 ILE A C 1 ATOM 1284 O O . ILE A 1 164 ? 8.534 32.756 13.323 1.00 23.89 ? 164 ILE A O 1 ATOM 1285 C CB . ILE A 1 164 ? 8.185 32.261 16.393 1.00 22.20 ? 164 ILE A CB 1 ATOM 1286 C CG1 . ILE A 1 164 ? 9.620 31.825 16.718 1.00 22.20 ? 164 ILE A CG1 1 ATOM 1287 C CG2 . ILE A 1 164 ? 7.374 31.146 15.716 1.00 23.02 ? 164 ILE A CG2 1 ATOM 1288 C CD1 . ILE A 1 164 ? 9.744 30.996 17.990 1.00 18.73 ? 164 ILE A CD1 1 ATOM 1289 N N . ASN A 1 165 ? 10.148 34.045 14.228 1.00 19.67 ? 165 ASN A N 1 ATOM 1290 C CA . ASN A 1 165 ? 11.040 33.956 13.077 1.00 21.81 ? 165 ASN A CA 1 ATOM 1291 C C . ASN A 1 165 ? 11.522 32.527 12.963 1.00 22.88 ? 165 ASN A C 1 ATOM 1292 O O . ASN A 1 165 ? 12.362 32.096 13.749 1.00 28.80 ? 165 ASN A O 1 ATOM 1293 C CB . ASN A 1 165 ? 12.218 34.918 13.227 1.00 20.05 ? 165 ASN A CB 1 ATOM 1294 C CG . ASN A 1 165 ? 13.301 34.678 12.195 1.00 24.02 ? 165 ASN A CG 1 ATOM 1295 O OD1 . ASN A 1 165 ? 14.149 33.805 12.365 1.00 25.67 ? 165 ASN A OD1 1 ATOM 1296 N ND2 . ASN A 1 165 ? 13.281 35.458 11.119 1.00 28.00 ? 165 ASN A ND2 1 ATOM 1297 N N . ASN A 1 166 ? 10.991 31.799 11.985 1.00 20.34 ? 166 ASN A N 1 ATOM 1298 C CA . ASN A 1 166 ? 11.087 30.339 11.988 1.00 25.34 ? 166 ASN A CA 1 ATOM 1299 C C . ASN A 1 166 ? 12.498 29.747 12.038 1.00 29.81 ? 166 ASN A C 1 ATOM 1300 O O . ASN A 1 166 ? 12.652 28.546 12.238 1.00 33.03 ? 166 ASN A O 1 ATOM 1301 C CB . ASN A 1 166 ? 10.264 29.721 10.852 1.00 26.85 ? 166 ASN A CB 1 ATOM 1302 C CG . ASN A 1 166 ? 10.780 30.083 9.481 1.00 29.80 ? 166 ASN A CG 1 ATOM 1303 O OD1 . ASN A 1 166 ? 11.934 30.484 9.317 1.00 29.13 ? 166 ASN A OD1 1 ATOM 1304 N ND2 . ASN A 1 166 ? 9.919 29.933 8.477 1.00 37.86 ? 166 ASN A ND2 1 ATOM 1305 N N . GLU A 1 167 ? 13.517 30.586 11.877 1.00 26.97 ? 167 GLU A N 1 ATOM 1306 C CA . GLU A 1 167 ? 14.899 30.124 11.985 1.00 25.33 ? 167 GLU A CA 1 ATOM 1307 C C . GLU A 1 167 ? 15.572 30.507 13.301 1.00 23.44 ? 167 GLU A C 1 ATOM 1308 O O . GLU A 1 167 ? 16.113 29.641 13.987 1.00 26.98 ? 167 GLU A O 1 ATOM 1309 C CB . GLU A 1 167 ? 15.730 30.597 10.796 1.00 26.22 ? 167 GLU A CB 1 ATOM 1310 C CG . GLU A 1 167 ? 15.383 29.887 9.501 1.00 31.65 ? 167 GLU A CG 1 ATOM 1311 C CD . GLU A 1 167 ? 16.306 30.250 8.348 1.00 41.72 ? 167 GLU A CD 1 ATOM 1312 O OE1 . GLU A 1 167 ? 17.455 30.680 8.603 1.00 45.74 ? 167 GLU A OE1 1 ATOM 1313 O OE2 . GLU A 1 167 ? 15.878 30.092 7.180 1.00 43.91 ? 167 GLU A OE2 1 ATOM 1314 N N . THR A 1 168 ? 15.530 31.793 13.650 1.00 20.47 ? 168 THR A N 1 ATOM 1315 C CA . THR A 1 168 ? 16.225 32.304 14.838 1.00 21.43 ? 168 THR A CA 1 ATOM 1316 C C . THR A 1 168 ? 15.480 32.030 16.135 1.00 23.67 ? 168 THR A C 1 ATOM 1317 O O . THR A 1 168 ? 16.078 32.033 17.212 1.00 28.34 ? 168 THR A O 1 ATOM 1318 C CB . THR A 1 168 ? 16.448 33.819 14.772 1.00 26.47 ? 168 THR A CB 1 ATOM 1319 O OG1 . THR A 1 168 ? 15.176 34.478 14.716 1.00 28.27 ? 168 THR A OG1 1 ATOM 1320 C CG2 . THR A 1 168 ? 17.299 34.201 13.561 1.00 32.16 ? 168 THR A CG2 1 ATOM 1321 N N . GLY A 1 169 ? 14.174 31.819 16.034 1.00 22.50 ? 169 GLY A N 1 ATOM 1322 C CA . GLY A 1 169 ? 13.360 31.525 17.203 1.00 21.91 ? 169 GLY A CA 1 ATOM 1323 C C . GLY A 1 169 ? 13.034 32.746 18.038 1.00 23.75 ? 169 GLY A C 1 ATOM 1324 O O . GLY A 1 169 ? 12.558 32.612 19.165 1.00 24.81 ? 169 GLY A O 1 ATOM 1325 N N . ASP A 1 170 ? 13.303 33.933 17.489 1.00 25.22 ? 170 ASP A N 1 ATOM 1326 C CA . ASP A 1 170 ? 12.895 35.200 18.102 1.00 24.81 ? 170 ASP A CA 1 ATOM 1327 C C . ASP A 1 170 ? 11.375 35.308 18.076 1.00 23.63 ? 170 ASP A C 1 ATOM 1328 O O . ASP A 1 170 ? 10.773 35.313 16.999 1.00 23.12 ? 170 ASP A O 1 ATOM 1329 C CB . ASP A 1 170 ? 13.483 36.398 17.340 1.00 26.59 ? 170 ASP A CB 1 ATOM 1330 C CG . ASP A 1 170 ? 15.012 36.449 17.374 1.00 33.62 ? 170 ASP A CG 1 ATOM 1331 O OD1 . ASP A 1 170 ? 15.590 37.010 16.416 1.00 30.93 ? 170 ASP A OD1 1 ATOM 1332 O OD2 . ASP A 1 170 ? 15.638 35.952 18.342 1.00 33.30 ? 170 ASP A OD2 1 ATOM 1333 N N . ILE A 1 171 ? 10.753 35.380 19.251 1.00 24.34 ? 171 ILE A N 1 ATOM 1334 C CA . ILE A 1 171 ? 9.315 35.634 19.332 1.00 20.35 ? 171 ILE A CA 1 ATOM 1335 C C . ILE A 1 171 ? 9.040 37.134 19.250 1.00 21.11 ? 171 ILE A C 1 ATOM 1336 O O . ILE A 1 171 ? 9.389 37.896 20.150 1.00 23.88 ? 171 ILE A O 1 ATOM 1337 C CB . ILE A 1 171 ? 8.678 35.042 20.592 1.00 16.04 ? 171 ILE A CB 1 ATOM 1338 C CG1 . ILE A 1 171 ? 9.031 33.562 20.702 1.00 20.20 ? 171 ILE A CG1 1 ATOM 1339 C CG2 . ILE A 1 171 ? 7.165 35.228 20.547 1.00 15.84 ? 171 ILE A CG2 1 ATOM 1340 C CD1 . ILE A 1 171 ? 8.402 32.857 21.886 1.00 24.81 ? 171 ILE A CD1 1 ATOM 1341 N N . ILE A 1 172 ? 8.420 37.536 18.147 1.00 19.87 ? 172 ILE A N 1 ATOM 1342 C CA . ILE A 1 172 ? 8.122 38.932 17.858 1.00 20.86 ? 172 ILE A CA 1 ATOM 1343 C C . ILE A 1 172 ? 6.609 39.101 17.714 1.00 25.66 ? 172 ILE A C 1 ATOM 1344 O O . ILE A 1 172 ? 5.919 38.194 17.238 1.00 24.42 ? 172 ILE A O 1 ATOM 1345 C CB . ILE A 1 172 ? 8.835 39.380 16.568 1.00 20.78 ? 172 ILE A CB 1 ATOM 1346 C CG1 . ILE A 1 172 ? 10.355 39.271 16.740 1.00 25.00 ? 172 ILE A CG1 1 ATOM 1347 C CG2 . ILE A 1 172 ? 8.431 40.794 16.179 1.00 23.43 ? 172 ILE A CG2 1 ATOM 1348 C CD1 . ILE A 1 172 ? 11.140 39.232 15.424 1.00 26.69 ? 172 ILE A CD1 1 ATOM 1349 N N . THR A 1 173 ? 6.099 40.256 18.132 1.00 22.71 ? 173 THR A N 1 ATOM 1350 C CA . THR A 1 173 ? 4.662 40.509 18.123 1.00 20.72 ? 173 THR A CA 1 ATOM 1351 C C . THR A 1 173 ? 4.166 41.022 16.766 1.00 20.98 ? 173 THR A C 1 ATOM 1352 O O . THR A 1 173 ? 4.905 41.686 16.046 1.00 21.99 ? 173 THR A O 1 ATOM 1353 C CB . THR A 1 173 ? 4.266 41.474 19.254 1.00 23.32 ? 173 THR A CB 1 ATOM 1354 O OG1 . THR A 1 173 ? 2.860 41.723 19.187 1.00 34.77 ? 173 THR A OG1 1 ATOM 1355 C CG2 . THR A 1 173 ? 5.022 42.799 19.151 1.00 22.75 ? 173 THR A CG2 1 ATOM 1356 N N . VAL A 1 174 ? 2.918 40.708 16.422 1.00 17.34 ? 174 VAL A N 1 ATOM 1357 C CA . VAL A 1 174 ? 2.356 41.090 15.116 1.00 16.48 ? 174 VAL A CA 1 ATOM 1358 C C . VAL A 1 174 ? 0.981 41.759 15.169 1.00 21.05 ? 174 VAL A C 1 ATOM 1359 O O . VAL A 1 174 ? 0.417 42.117 14.128 1.00 20.27 ? 174 VAL A O 1 ATOM 1360 C CB . VAL A 1 174 ? 2.264 39.900 14.148 1.00 12.05 ? 174 VAL A CB 1 ATOM 1361 C CG1 . VAL A 1 174 ? 3.630 39.561 13.604 1.00 17.31 ? 174 VAL A CG1 1 ATOM 1362 C CG2 . VAL A 1 174 ? 1.620 38.708 14.821 1.00 17.58 ? 174 VAL A CG2 1 ATOM 1363 N N . ALA A 1 175 ? 0.443 41.915 16.372 1.00 21.70 ? 175 ALA A N 1 ATOM 1364 C CA . ALA A 1 175 ? -0.868 42.523 16.547 1.00 21.33 ? 175 ALA A CA 1 ATOM 1365 C C . ALA A 1 175 ? -0.790 43.717 17.478 1.00 24.72 ? 175 ALA A C 1 ATOM 1366 O O . ALA A 1 175 ? 0.265 44.016 18.047 1.00 22.97 ? 175 ALA A O 1 ATOM 1367 C CB . ALA A 1 175 ? -1.866 41.503 17.072 1.00 22.57 ? 175 ALA A CB 1 ATOM 1368 N N . ALA A 1 176 ? -1.918 44.403 17.613 1.00 23.88 ? 176 ALA A N 1 ATOM 1369 C CA . ALA A 1 176 ? -2.035 45.505 18.542 1.00 22.40 ? 176 ALA A CA 1 ATOM 1370 C C . ALA A 1 176 ? -3.178 45.241 19.508 1.00 22.32 ? 176 ALA A C 1 ATOM 1371 O O . ALA A 1 176 ? -4.185 44.626 19.150 1.00 21.63 ? 176 ALA A O 1 ATOM 1372 C CB . ALA A 1 176 ? -2.257 46.795 17.793 1.00 25.26 ? 176 ALA A CB 1 ATOM 1373 N N . GLY A 1 177 ? -3.013 45.711 20.737 1.00 22.42 ? 177 GLY A N 1 ATOM 1374 C CA . GLY A 1 177 ? -4.026 45.533 21.764 1.00 25.37 ? 177 GLY A CA 1 ATOM 1375 C C . GLY A 1 177 ? -3.467 44.850 22.991 1.00 26.37 ? 177 GLY A C 1 ATOM 1376 O O . GLY A 1 177 ? -4.209 44.230 23.754 1.00 29.00 ? 177 GLY A O 1 ATOM 1377 N N . LEU A 1 178 ? -2.155 44.955 23.180 1.00 19.60 ? 178 LEU A N 1 ATOM 1378 C CA . LEU A 1 178 ? -1.532 44.402 24.365 1.00 22.19 ? 178 LEU A CA 1 ATOM 1379 C C . LEU A 1 178 ? -1.853 45.325 25.529 1.00 26.66 ? 178 LEU A C 1 ATOM 1380 O O . LEU A 1 178 ? -1.198 46.349 25.726 1.00 25.63 ? 178 LEU A O 1 ATOM 1381 C CB . LEU A 1 178 ? -0.022 44.243 24.176 1.00 24.86 ? 178 LEU A CB 1 ATOM 1382 C CG . LEU A 1 178 ? 0.484 43.111 23.279 1.00 17.47 ? 178 LEU A CG 1 ATOM 1383 C CD1 . LEU A 1 178 ? 1.980 43.234 23.091 1.00 15.54 ? 178 LEU A CD1 1 ATOM 1384 C CD2 . LEU A 1 178 ? 0.135 41.746 23.840 1.00 15.54 ? 178 LEU A CD2 1 ATOM 1385 N N . ASP A 1 179 ? -2.890 44.957 26.278 1.00 29.96 ? 179 ASP A N 1 ATOM 1386 C CA . ASP A 1 179 ? -3.415 45.794 27.355 1.00 33.84 ? 179 ASP A CA 1 ATOM 1387 C C . ASP A 1 179 ? -3.403 45.045 28.680 1.00 29.56 ? 179 ASP A C 1 ATOM 1388 O O . ASP A 1 179 ? -4.266 44.198 28.938 1.00 31.65 ? 179 ASP A O 1 ATOM 1389 C CB . ASP A 1 179 ? -4.837 46.280 27.016 1.00 36.70 ? 179 ASP A CB 1 ATOM 1390 C CG . ASP A 1 179 ? -5.435 47.181 28.098 1.00 34.64 ? 179 ASP A CG 1 ATOM 1391 O OD1 . ASP A 1 179 ? -4.679 47.949 28.734 1.00 33.25 ? 179 ASP A OD1 1 ATOM 1392 O OD2 . ASP A 1 179 ? -6.668 47.131 28.306 1.00 35.39 ? 179 ASP A OD2 1 ATOM 1393 N N . ARG A 1 180 ? -2.424 45.376 29.517 1.00 27.22 ? 180 ARG A N 1 ATOM 1394 C CA . ARG A 1 180 ? -2.274 44.759 30.831 1.00 29.10 ? 180 ARG A CA 1 ATOM 1395 C C . ARG A 1 180 ? -3.579 44.745 31.634 1.00 30.47 ? 180 ARG A C 1 ATOM 1396 O O . ARG A 1 180 ? -3.921 43.735 32.247 1.00 33.39 ? 180 ARG A O 1 ATOM 1397 C CB . ARG A 1 180 ? -1.163 45.447 31.624 1.00 23.05 ? 180 ARG A CB 1 ATOM 1398 C CG . ARG A 1 180 ? -1.168 45.111 33.096 1.00 28.42 ? 180 ARG A CG 1 ATOM 1399 C CD . ARG A 1 180 ? -0.591 46.247 33.916 1.00 35.74 ? 180 ARG A CD 1 ATOM 1400 N NE . ARG A 1 180 ? -1.424 46.563 35.075 1.00 32.49 ? 180 ARG A NE 1 ATOM 1401 C CZ . ARG A 1 180 ? -1.457 45.852 36.198 1.00 43.13 ? 180 ARG A CZ 1 ATOM 1402 N NH1 . ARG A 1 180 ? -0.695 44.767 36.335 1.00 43.71 ? 180 ARG A NH1 1 ATOM 1403 N NH2 . ARG A 1 180 ? -2.257 46.229 37.188 1.00 46.02 ? 180 ARG A NH2 1 ATOM 1404 N N . GLU A 1 181 ? -4.314 45.854 31.613 1.00 29.66 ? 181 GLU A N 1 ATOM 1405 C CA . GLU A 1 181 ? -5.555 45.954 32.385 1.00 31.14 ? 181 GLU A CA 1 ATOM 1406 C C . GLU A 1 181 ? -6.685 45.054 31.861 1.00 34.11 ? 181 GLU A C 1 ATOM 1407 O O . GLU A 1 181 ? -7.799 45.078 32.394 1.00 31.71 ? 181 GLU A O 1 ATOM 1408 C CB . GLU A 1 181 ? -6.023 47.409 32.487 1.00 28.02 ? 181 GLU A CB 1 ATOM 1409 C CG . GLU A 1 181 ? -5.166 48.284 33.395 1.00 32.36 ? 181 GLU A CG 1 ATOM 1410 C CD . GLU A 1 181 ? -3.936 48.853 32.699 1.00 31.06 ? 181 GLU A CD 1 ATOM 1411 O OE1 . GLU A 1 181 ? -4.016 49.180 31.497 1.00 29.48 ? 181 GLU A OE1 1 ATOM 1412 O OE2 . GLU A 1 181 ? -2.883 48.989 33.359 1.00 28.87 ? 181 GLU A OE2 1 ATOM 1413 N N . LYS A 1 182 ? -6.386 44.261 30.830 1.00 28.68 ? 182 LYS A N 1 ATOM 1414 C CA . LYS A 1 182 ? -7.344 43.305 30.273 1.00 30.42 ? 182 LYS A CA 1 ATOM 1415 C C . LYS A 1 182 ? -6.812 41.867 30.311 1.00 37.78 ? 182 LYS A C 1 ATOM 1416 O O . LYS A 1 182 ? -7.417 40.989 30.938 1.00 37.64 ? 182 LYS A O 1 ATOM 1417 C CB . LYS A 1 182 ? -7.739 43.696 28.843 1.00 33.81 ? 182 LYS A CB 1 ATOM 1418 C CG . LYS A 1 182 ? -8.952 44.627 28.734 1.00 36.07 ? 182 LYS A CG 1 ATOM 1419 C CD . LYS A 1 182 ? -9.126 45.134 27.294 1.00 43.14 ? 182 LYS A CD 1 ATOM 1420 C CE . LYS A 1 182 ? -10.365 46.007 27.119 1.00 35.96 ? 182 LYS A CE 1 ATOM 1421 N NZ . LYS A 1 182 ? -10.313 46.763 25.832 1.00 34.81 ? 182 LYS A NZ 1 ATOM 1422 N N . VAL A 1 183 ? -5.693 41.635 29.623 1.00 40.06 ? 183 VAL A N 1 ATOM 1423 C CA . VAL A 1 183 ? -5.013 40.336 29.616 1.00 33.85 ? 183 VAL A CA 1 ATOM 1424 C C . VAL A 1 183 ? -3.547 40.552 29.978 1.00 32.19 ? 183 VAL A C 1 ATOM 1425 O O . VAL A 1 183 ? -2.777 41.116 29.196 1.00 33.30 ? 183 VAL A O 1 ATOM 1426 C CB . VAL A 1 183 ? -5.136 39.623 28.253 1.00 29.59 ? 183 VAL A CB 1 ATOM 1427 C CG1 . VAL A 1 183 ? -4.248 38.386 28.214 1.00 29.34 ? 183 VAL A CG1 1 ATOM 1428 C CG2 . VAL A 1 183 ? -6.589 39.241 27.978 1.00 36.47 ? 183 VAL A CG2 1 ATOM 1429 N N . GLN A 1 184 ? -3.174 40.101 31.170 1.00 30.27 ? 184 GLN A N 1 ATOM 1430 C CA . GLN A 1 184 ? -1.897 40.478 31.779 1.00 33.41 ? 184 GLN A CA 1 ATOM 1431 C C . GLN A 1 184 ? -0.750 39.505 31.448 1.00 33.02 ? 184 GLN A C 1 ATOM 1432 O O . GLN A 1 184 ? 0.430 39.823 31.655 1.00 30.83 ? 184 GLN A O 1 ATOM 1433 C CB . GLN A 1 184 ? -2.104 40.694 33.292 1.00 36.42 ? 184 GLN A CB 1 ATOM 1434 C CG . GLN A 1 184 ? -0.857 40.865 34.147 1.00 43.14 ? 184 GLN A CG 1 ATOM 1435 C CD . GLN A 1 184 ? -0.557 39.617 34.966 1.00 59.80 ? 184 GLN A CD 1 ATOM 1436 O OE1 . GLN A 1 184 ? -1.464 39.007 35.543 1.00 58.01 ? 184 GLN A OE1 1 ATOM 1437 N NE2 . GLN A 1 184 ? 0.719 39.234 35.026 1.00 57.98 ? 184 GLN A NE2 1 ATOM 1438 N N . GLN A 1 185 ? -1.105 38.345 30.893 1.00 27.81 ? 185 GLN A N 1 ATOM 1439 C CA . GLN A 1 185 ? -0.134 37.296 30.593 1.00 26.84 ? 185 GLN A CA 1 ATOM 1440 C C . GLN A 1 185 ? -0.633 36.320 29.531 1.00 31.35 ? 185 GLN A C 1 ATOM 1441 O O . GLN A 1 185 ? -1.792 35.899 29.554 1.00 30.63 ? 185 GLN A O 1 ATOM 1442 C CB . GLN A 1 185 ? 0.209 36.542 31.875 1.00 35.74 ? 185 GLN A CB 1 ATOM 1443 C CG . GLN A 1 185 ? 1.267 35.463 31.748 1.00 32.73 ? 185 GLN A CG 1 ATOM 1444 C CD . GLN A 1 185 ? 1.563 34.820 33.083 1.00 29.67 ? 185 GLN A CD 1 ATOM 1445 O OE1 . GLN A 1 185 ? 0.945 33.823 33.448 1.00 22.62 ? 185 GLN A OE1 1 ATOM 1446 N NE2 . GLN A 1 185 ? 2.489 35.409 33.835 1.00 27.37 ? 185 GLN A NE2 1 ATOM 1447 N N . TYR A 1 186 ? 0.264 35.964 28.614 1.00 29.47 ? 186 TYR A N 1 ATOM 1448 C CA . TYR A 1 186 ? -0.025 35.016 27.543 1.00 23.30 ? 186 TYR A CA 1 ATOM 1449 C C . TYR A 1 186 ? 0.846 33.781 27.659 1.00 30.82 ? 186 TYR A C 1 ATOM 1450 O O . TYR A 1 186 ? 2.029 33.879 28.004 1.00 34.53 ? 186 TYR A O 1 ATOM 1451 C CB . TYR A 1 186 ? 0.235 35.660 26.187 1.00 23.79 ? 186 TYR A CB 1 ATOM 1452 C CG . TYR A 1 186 ? -0.778 36.703 25.802 1.00 26.93 ? 186 TYR A CG 1 ATOM 1453 C CD1 . TYR A 1 186 ? -2.004 36.336 25.248 1.00 27.08 ? 186 TYR A CD1 1 ATOM 1454 C CD2 . TYR A 1 186 ? -0.511 38.058 25.983 1.00 24.10 ? 186 TYR A CD2 1 ATOM 1455 C CE1 . TYR A 1 186 ? -2.939 37.293 24.890 1.00 26.23 ? 186 TYR A CE1 1 ATOM 1456 C CE2 . TYR A 1 186 ? -1.440 39.019 25.630 1.00 20.44 ? 186 TYR A CE2 1 ATOM 1457 C CZ . TYR A 1 186 ? -2.649 38.631 25.083 1.00 22.99 ? 186 TYR A CZ 1 ATOM 1458 O OH . TYR A 1 186 ? -3.574 39.580 24.731 1.00 26.75 ? 186 TYR A OH 1 ATOM 1459 N N . THR A 1 187 ? 0.261 32.625 27.360 1.00 25.63 ? 187 THR A N 1 ATOM 1460 C CA . THR A 1 187 ? 1.004 31.372 27.329 1.00 23.18 ? 187 THR A CA 1 ATOM 1461 C C . THR A 1 187 ? 1.045 30.852 25.901 1.00 27.08 ? 187 THR A C 1 ATOM 1462 O O . THR A 1 187 ? 0.009 30.731 25.244 1.00 31.40 ? 187 THR A O 1 ATOM 1463 C CB . THR A 1 187 ? 0.383 30.311 28.265 1.00 29.55 ? 187 THR A CB 1 ATOM 1464 O OG1 . THR A 1 187 ? 0.248 30.855 29.584 1.00 38.84 ? 187 THR A OG1 1 ATOM 1465 C CG2 . THR A 1 187 ? 1.264 29.072 28.340 1.00 30.21 ? 187 THR A CG2 1 ATOM 1466 N N . LEU A 1 188 ? 2.250 30.551 25.428 1.00 29.34 ? 188 LEU A N 1 ATOM 1467 C CA . LEU A 1 188 ? 2.456 30.077 24.062 1.00 28.59 ? 188 LEU A CA 1 ATOM 1468 C C . LEU A 1 188 ? 3.069 28.687 24.009 1.00 28.55 ? 188 LEU A C 1 ATOM 1469 O O . LEU A 1 188 ? 4.000 28.382 24.756 1.00 29.04 ? 188 LEU A O 1 ATOM 1470 C CB . LEU A 1 188 ? 3.363 31.040 23.301 1.00 23.14 ? 188 LEU A CB 1 ATOM 1471 C CG . LEU A 1 188 ? 2.831 32.435 23.015 1.00 20.42 ? 188 LEU A CG 1 ATOM 1472 C CD1 . LEU A 1 188 ? 3.923 33.261 22.382 1.00 22.29 ? 188 LEU A CD1 1 ATOM 1473 C CD2 . LEU A 1 188 ? 1.639 32.343 22.099 1.00 23.74 ? 188 LEU A CD2 1 ATOM 1474 N N . ILE A 1 189 ? 2.542 27.855 23.116 1.00 25.12 ? 189 ILE A N 1 ATOM 1475 C CA . ILE A 1 189 ? 3.136 26.558 22.818 1.00 24.97 ? 189 ILE A CA 1 ATOM 1476 C C . ILE A 1 189 ? 4.000 26.697 21.561 1.00 24.36 ? 189 ILE A C 1 ATOM 1477 O O . ILE A 1 189 ? 3.478 26.857 20.457 1.00 27.09 ? 189 ILE A O 1 ATOM 1478 C CB . ILE A 1 189 ? 2.050 25.468 22.619 1.00 23.13 ? 189 ILE A CB 1 ATOM 1479 C CG1 . ILE A 1 189 ? 1.208 25.294 23.891 1.00 23.76 ? 189 ILE A CG1 1 ATOM 1480 C CG2 . ILE A 1 189 ? 2.670 24.143 22.152 1.00 23.46 ? 189 ILE A CG2 1 ATOM 1481 C CD1 . ILE A 1 189 ? 1.814 24.404 24.962 1.00 29.33 ? 189 ILE A CD1 1 ATOM 1482 N N . ILE A 1 190 ? 5.317 26.658 21.743 1.00 19.89 ? 190 ILE A N 1 ATOM 1483 C CA . ILE A 1 190 ? 6.260 26.741 20.633 1.00 17.81 ? 190 ILE A CA 1 ATOM 1484 C C . ILE A 1 190 ? 6.587 25.339 20.159 1.00 24.25 ? 190 ILE A C 1 ATOM 1485 O O . ILE A 1 190 ? 6.702 24.428 20.976 1.00 31.65 ? 190 ILE A O 1 ATOM 1486 C CB . ILE A 1 190 ? 7.581 27.399 21.060 1.00 17.02 ? 190 ILE A CB 1 ATOM 1487 C CG1 . ILE A 1 190 ? 7.335 28.685 21.864 1.00 23.78 ? 190 ILE A CG1 1 ATOM 1488 C CG2 . ILE A 1 190 ? 8.489 27.620 19.854 1.00 22.38 ? 190 ILE A CG2 1 ATOM 1489 C CD1 . ILE A 1 190 ? 6.510 29.752 21.163 1.00 27.04 ? 190 ILE A CD1 1 ATOM 1490 N N . GLN A 1 191 ? 6.747 25.160 18.851 1.00 21.42 ? 191 GLN A N 1 ATOM 1491 C CA . GLN A 1 191 ? 7.090 23.847 18.313 1.00 26.61 ? 191 GLN A CA 1 ATOM 1492 C C . GLN A 1 191 ? 8.329 23.871 17.437 1.00 30.93 ? 191 GLN A C 1 ATOM 1493 O O . GLN A 1 191 ? 8.483 24.738 16.573 1.00 34.29 ? 191 GLN A O 1 ATOM 1494 C CB . GLN A 1 191 ? 5.927 23.256 17.521 1.00 25.85 ? 191 GLN A CB 1 ATOM 1495 C CG . GLN A 1 191 ? 6.073 21.763 17.254 1.00 26.27 ? 191 GLN A CG 1 ATOM 1496 C CD . GLN A 1 191 ? 5.312 21.303 16.031 1.00 27.95 ? 191 GLN A CD 1 ATOM 1497 O OE1 . GLN A 1 191 ? 5.441 21.884 14.952 1.00 30.53 ? 191 GLN A OE1 1 ATOM 1498 N NE2 . GLN A 1 191 ? 4.525 20.242 16.187 1.00 24.79 ? 191 GLN A NE2 1 ATOM 1499 N N . ALA A 1 192 ? 9.203 22.897 17.656 1.00 30.03 ? 192 ALA A N 1 ATOM 1500 C CA . ALA A 1 192 ? 10.395 22.746 16.842 1.00 28.15 ? 192 ALA A CA 1 ATOM 1501 C C . ALA A 1 192 ? 10.254 21.530 15.938 1.00 27.76 ? 192 ALA A C 1 ATOM 1502 O O . ALA A 1 192 ? 9.911 20.443 16.401 1.00 32.11 ? 192 ALA A O 1 ATOM 1503 C CB . ALA A 1 192 ? 11.623 22.624 17.726 1.00 25.54 ? 192 ALA A CB 1 ATOM 1504 N N . THR A 1 193 ? 10.500 21.724 14.648 1.00 22.94 ? 193 THR A N 1 ATOM 1505 C CA . THR A 1 193 ? 10.486 20.623 13.694 1.00 26.40 ? 193 THR A CA 1 ATOM 1506 C C . THR A 1 193 ? 11.792 20.625 12.918 1.00 26.48 ? 193 THR A C 1 ATOM 1507 O O . THR A 1 193 ? 12.168 21.638 12.327 1.00 28.58 ? 193 THR A O 1 ATOM 1508 C CB . THR A 1 193 ? 9.293 20.719 12.715 1.00 27.99 ? 193 THR A CB 1 ATOM 1509 O OG1 . THR A 1 193 ? 8.068 20.803 13.452 1.00 36.82 ? 193 THR A OG1 1 ATOM 1510 C CG2 . THR A 1 193 ? 9.236 19.507 11.805 1.00 28.22 ? 193 THR A CG2 1 ATOM 1511 N N . ASP A 1 194 ? 12.482 19.488 12.931 1.00 28.09 ? 194 ASP A N 1 ATOM 1512 C CA . ASP A 1 194 ? 13.726 19.333 12.189 1.00 24.43 ? 194 ASP A CA 1 ATOM 1513 C C . ASP A 1 194 ? 13.431 19.109 10.716 1.00 22.36 ? 194 ASP A C 1 ATOM 1514 O O . ASP A 1 194 ? 12.306 19.309 10.269 1.00 25.86 ? 194 ASP A O 1 ATOM 1515 C CB . ASP A 1 194 ? 14.563 18.186 12.764 1.00 25.26 ? 194 ASP A CB 1 ATOM 1516 C CG . ASP A 1 194 ? 13.880 16.835 12.647 1.00 29.03 ? 194 ASP A CG 1 ATOM 1517 O OD1 . ASP A 1 194 ? 12.749 16.763 12.127 1.00 30.26 ? 194 ASP A OD1 1 ATOM 1518 O OD2 . ASP A 1 194 ? 14.486 15.833 13.079 1.00 31.23 ? 194 ASP A OD2 1 ATOM 1519 N N . MET A 1 195 ? 14.443 18.685 9.969 1.00 24.19 ? 195 MET A N 1 ATOM 1520 C CA . MET A 1 195 ? 14.318 18.473 8.533 1.00 25.98 ? 195 MET A CA 1 ATOM 1521 C C . MET A 1 195 ? 13.870 19.751 7.843 1.00 23.47 ? 195 MET A C 1 ATOM 1522 O O . MET A 1 195 ? 13.102 19.710 6.880 1.00 25.34 ? 195 MET A O 1 ATOM 1523 C CB . MET A 1 195 ? 13.349 17.322 8.233 1.00 31.06 ? 195 MET A CB 1 ATOM 1524 C CG . MET A 1 195 ? 13.913 15.940 8.500 1.00 33.73 ? 195 MET A CG 1 ATOM 1525 S SD . MET A 1 195 ? 15.364 15.583 7.488 1.00 33.28 ? 195 MET A SD 1 ATOM 1526 C CE . MET A 1 195 ? 15.214 13.800 7.326 1.00 35.45 ? 195 MET A CE 1 ATOM 1527 N N . GLU A 1 196 ? 14.371 20.879 8.347 1.00 26.12 ? 196 GLU A N 1 ATOM 1528 C CA . GLU A 1 196 ? 13.958 22.223 7.915 1.00 28.92 ? 196 GLU A CA 1 ATOM 1529 C C . GLU A 1 196 ? 12.440 22.409 7.945 1.00 26.38 ? 196 GLU A C 1 ATOM 1530 O O . GLU A 1 196 ? 11.838 22.889 6.983 1.00 21.45 ? 196 GLU A O 1 ATOM 1531 C CB . GLU A 1 196 ? 14.543 22.585 6.544 1.00 27.60 ? 196 GLU A CB 1 ATOM 1532 C CG . GLU A 1 196 ? 16.019 22.949 6.592 1.00 34.49 ? 196 GLU A CG 1 ATOM 1533 C CD . GLU A 1 196 ? 16.655 23.032 5.215 1.00 45.04 ? 196 GLU A CD 1 ATOM 1534 O OE1 . GLU A 1 196 ? 15.974 22.708 4.211 1.00 37.63 ? 196 GLU A OE1 1 ATOM 1535 O OE2 . GLU A 1 196 ? 17.844 23.421 5.142 1.00 48.20 ? 196 GLU A OE2 1 ATOM 1536 N N . GLY A 1 197 ? 11.842 22.016 9.066 1.00 28.74 ? 197 GLY A N 1 ATOM 1537 C CA . GLY A 1 197 ? 10.416 22.188 9.306 1.00 28.02 ? 197 GLY A CA 1 ATOM 1538 C C . GLY A 1 197 ? 9.511 21.481 8.321 1.00 30.53 ? 197 GLY A C 1 ATOM 1539 O O . GLY A 1 197 ? 8.351 21.862 8.170 1.00 36.67 ? 197 GLY A O 1 ATOM 1540 N N . ASN A 1 198 ? 10.034 20.456 7.652 1.00 25.13 ? 198 ASN A N 1 ATOM 1541 C CA . ASN A 1 198 ? 9.239 19.678 6.713 1.00 27.17 ? 198 ASN A CA 1 ATOM 1542 C C . ASN A 1 198 ? 8.092 18.978 7.430 1.00 38.05 ? 198 ASN A C 1 ATOM 1543 O O . ASN A 1 198 ? 8.326 18.213 8.370 1.00 38.72 ? 198 ASN A O 1 ATOM 1544 C CB . ASN A 1 198 ? 10.099 18.660 5.969 1.00 30.43 ? 198 ASN A CB 1 ATOM 1545 C CG . ASN A 1 198 ? 9.322 17.919 4.905 1.00 36.23 ? 198 ASN A CG 1 ATOM 1546 O OD1 . ASN A 1 198 ? 8.474 17.073 5.202 1.00 33.25 ? 198 ASN A OD1 1 ATOM 1547 N ND2 . ASN A 1 198 ? 9.604 18.239 3.650 1.00 41.45 ? 198 ASN A ND2 1 ATOM 1548 N N . PRO A 1 199 ? 6.848 19.232 6.984 1.00 38.98 ? 199 PRO A N 1 ATOM 1549 C CA . PRO A 1 199 ? 5.656 18.755 7.688 1.00 37.52 ? 199 PRO A CA 1 ATOM 1550 C C . PRO A 1 199 ? 5.493 17.236 7.676 1.00 42.13 ? 199 PRO A C 1 ATOM 1551 O O . PRO A 1 199 ? 5.103 16.662 8.691 1.00 43.88 ? 199 PRO A O 1 ATOM 1552 C CB . PRO A 1 199 ? 4.503 19.424 6.929 1.00 34.96 ? 199 PRO A CB 1 ATOM 1553 C CG . PRO A 1 199 ? 5.141 20.509 6.117 1.00 41.46 ? 199 PRO A CG 1 ATOM 1554 C CD . PRO A 1 199 ? 6.491 19.991 5.776 1.00 35.52 ? 199 PRO A CD 1 ATOM 1555 N N . THR A 1 200 ? 5.798 16.590 6.555 1.00 39.95 ? 200 THR A N 1 ATOM 1556 C CA . THR A 1 200 ? 5.571 15.147 6.442 1.00 47.06 ? 200 THR A CA 1 ATOM 1557 C C . THR A 1 200 ? 6.748 14.316 6.967 1.00 45.94 ? 200 THR A C 1 ATOM 1558 O O . THR A 1 200 ? 6.547 13.248 7.549 1.00 37.71 ? 200 THR A O 1 ATOM 1559 C CB . THR A 1 200 ? 5.220 14.714 4.992 1.00 45.39 ? 200 THR A CB 1 ATOM 1560 O OG1 . THR A 1 200 ? 6.422 14.512 4.237 1.00 50.16 ? 200 THR A OG1 1 ATOM 1561 C CG2 . THR A 1 200 ? 4.330 15.757 4.299 1.00 41.01 ? 200 THR A CG2 1 ATOM 1562 N N . TYR A 1 201 ? 7.966 14.815 6.765 1.00 45.80 ? 201 TYR A N 1 ATOM 1563 C CA . TYR A 1 201 ? 9.185 14.078 7.113 1.00 42.06 ? 201 TYR A CA 1 ATOM 1564 C C . TYR A 1 201 ? 9.787 14.433 8.472 1.00 37.31 ? 201 TYR A C 1 ATOM 1565 O O . TYR A 1 201 ? 10.433 13.596 9.103 1.00 34.46 ? 201 TYR A O 1 ATOM 1566 C CB . TYR A 1 201 ? 10.257 14.284 6.041 1.00 42.98 ? 201 TYR A CB 1 ATOM 1567 C CG . TYR A 1 201 ? 10.034 13.515 4.762 1.00 51.80 ? 201 TYR A CG 1 ATOM 1568 C CD1 . TYR A 1 201 ? 10.055 14.166 3.526 1.00 52.21 ? 201 TYR A CD1 1 ATOM 1569 C CD2 . TYR A 1 201 ? 9.815 12.131 4.781 1.00 55.43 ? 201 TYR A CD2 1 ATOM 1570 C CE1 . TYR A 1 201 ? 9.861 13.460 2.340 1.00 62.23 ? 201 TYR A CE1 1 ATOM 1571 C CE2 . TYR A 1 201 ? 9.616 11.415 3.602 1.00 61.57 ? 201 TYR A CE2 1 ATOM 1572 C CZ . TYR A 1 201 ? 9.641 12.086 2.386 1.00 69.32 ? 201 TYR A CZ 1 ATOM 1573 O OH . TYR A 1 201 ? 9.449 11.384 1.217 1.00 73.56 ? 201 TYR A OH 1 ATOM 1574 N N . GLY A 1 202 ? 9.591 15.675 8.906 1.00 35.67 ? 202 GLY A N 1 ATOM 1575 C CA . GLY A 1 202 ? 10.228 16.183 10.117 1.00 31.21 ? 202 GLY A CA 1 ATOM 1576 C C . GLY A 1 202 ? 9.696 15.631 11.427 1.00 31.81 ? 202 GLY A C 1 ATOM 1577 O O . GLY A 1 202 ? 8.505 15.345 11.563 1.00 31.80 ? 202 GLY A O 1 ATOM 1578 N N . LEU A 1 203 ? 10.601 15.479 12.387 1.00 30.17 ? 203 LEU A N 1 ATOM 1579 C CA . LEU A 1 203 ? 10.255 15.077 13.742 1.00 31.68 ? 203 LEU A CA 1 ATOM 1580 C C . LEU A 1 203 ? 10.085 16.341 14.570 1.00 30.22 ? 203 LEU A C 1 ATOM 1581 O O . LEU A 1 203 ? 10.895 17.265 14.477 1.00 27.38 ? 203 LEU A O 1 ATOM 1582 C CB . LEU A 1 203 ? 11.357 14.200 14.345 1.00 31.02 ? 203 LEU A CB 1 ATOM 1583 C CG . LEU A 1 203 ? 11.920 13.010 13.560 1.00 26.94 ? 203 LEU A CG 1 ATOM 1584 C CD1 . LEU A 1 203 ? 13.308 12.677 14.067 1.00 25.12 ? 203 LEU A CD1 1 ATOM 1585 C CD2 . LEU A 1 203 ? 11.007 11.796 13.640 1.00 24.86 ? 203 LEU A CD2 1 ATOM 1586 N N . SER A 1 204 ? 9.037 16.372 15.386 1.00 36.20 ? 204 SER A N 1 ATOM 1587 C CA . SER A 1 204 ? 8.663 17.587 16.106 1.00 32.56 ? 204 SER A CA 1 ATOM 1588 C C . SER A 1 204 ? 8.650 17.424 17.620 1.00 29.47 ? 204 SER A C 1 ATOM 1589 O O . SER A 1 204 ? 8.522 16.316 18.139 1.00 33.24 ? 204 SER A O 1 ATOM 1590 C CB . SER A 1 204 ? 7.300 18.092 15.625 1.00 35.07 ? 204 SER A CB 1 ATOM 1591 O OG . SER A 1 204 ? 7.295 18.279 14.220 1.00 39.90 ? 204 SER A OG 1 ATOM 1592 N N . ASN A 1 205 ? 8.781 18.550 18.314 1.00 31.21 ? 205 ASN A N 1 ATOM 1593 C CA . ASN A 1 205 ? 8.779 18.601 19.771 1.00 29.47 ? 205 ASN A CA 1 ATOM 1594 C C . ASN A 1 205 ? 8.540 20.041 20.223 1.00 29.14 ? 205 ASN A C 1 ATOM 1595 O O . ASN A 1 205 ? 8.897 20.985 19.515 1.00 27.91 ? 205 ASN A O 1 ATOM 1596 C CB . ASN A 1 205 ? 10.103 18.074 20.323 1.00 28.01 ? 205 ASN A CB 1 ATOM 1597 C CG . ASN A 1 205 ? 10.020 17.681 21.785 1.00 30.27 ? 205 ASN A CG 1 ATOM 1598 O OD1 . ASN A 1 205 ? 8.934 17.583 22.359 1.00 33.20 ? 205 ASN A OD1 1 ATOM 1599 N ND2 . ASN A 1 205 ? 11.177 17.444 22.394 1.00 32.80 ? 205 ASN A ND2 1 ATOM 1600 N N . THR A 1 206 ? 7.940 20.203 21.398 1.00 27.52 ? 206 THR A N 1 ATOM 1601 C CA . THR A 1 206 ? 7.450 21.506 21.834 1.00 25.80 ? 206 THR A CA 1 ATOM 1602 C C . THR A 1 206 ? 8.120 22.011 23.105 1.00 29.73 ? 206 THR A C 1 ATOM 1603 O O . THR A 1 206 ? 8.885 21.293 23.749 1.00 36.12 ? 206 THR A O 1 ATOM 1604 C CB . THR A 1 206 ? 5.951 21.460 22.164 1.00 26.54 ? 206 THR A CB 1 ATOM 1605 O OG1 . THR A 1 206 ? 5.802 21.036 23.531 1.00 29.84 ? 206 THR A OG1 1 ATOM 1606 C CG2 . THR A 1 206 ? 5.176 20.566 21.176 1.00 27.42 ? 206 THR A CG2 1 ATOM 1607 N N . ALA A 1 207 ? 7.800 23.257 23.452 1.00 28.94 ? 207 ALA A N 1 ATOM 1608 C CA . ALA A 1 207 ? 8.060 23.836 24.772 1.00 31.00 ? 207 ALA A CA 1 ATOM 1609 C C . ALA A 1 207 ? 6.985 24.892 25.077 1.00 30.80 ? 207 ALA A C 1 ATOM 1610 O O . ALA A 1 207 ? 6.044 25.075 24.298 1.00 29.04 ? 207 ALA A O 1 ATOM 1611 C CB . ALA A 1 207 ? 9.455 24.448 24.829 1.00 27.09 ? 207 ALA A CB 1 ATOM 1612 N N . THR A 1 208 ? 7.111 25.576 26.210 1.00 28.11 ? 208 THR A N 1 ATOM 1613 C CA . THR A 1 208 ? 6.212 26.684 26.517 1.00 25.39 ? 208 THR A CA 1 ATOM 1614 C C . THR A 1 208 ? 6.923 28.006 26.723 1.00 29.21 ? 208 THR A C 1 ATOM 1615 O O . THR A 1 208 ? 7.957 28.078 27.391 1.00 29.50 ? 208 THR A O 1 ATOM 1616 C CB . THR A 1 208 ? 5.315 26.415 27.731 1.00 30.43 ? 208 THR A CB 1 ATOM 1617 O OG1 . THR A 1 208 ? 5.856 25.330 28.514 1.00 40.30 ? 208 THR A OG1 1 ATOM 1618 C CG2 . THR A 1 208 ? 3.897 26.141 27.259 1.00 36.21 ? 208 THR A CG2 1 ATOM 1619 N N . ALA A 1 209 ? 6.350 29.046 26.126 1.00 28.17 ? 209 ALA A N 1 ATOM 1620 C CA . ALA A 1 209 ? 6.786 30.411 26.339 1.00 25.29 ? 209 ALA A CA 1 ATOM 1621 C C . ALA A 1 209 ? 5.672 31.147 27.069 1.00 28.75 ? 209 ALA A C 1 ATOM 1622 O O . ALA A 1 209 ? 4.541 31.215 26.583 1.00 34.21 ? 209 ALA A O 1 ATOM 1623 C CB . ALA A 1 209 ? 7.099 31.077 25.017 1.00 21.16 ? 209 ALA A CB 1 ATOM 1624 N N . VAL A 1 210 ? 5.986 31.667 28.250 1.00 26.35 ? 210 VAL A N 1 ATOM 1625 C CA . VAL A 1 210 ? 5.017 32.418 29.038 1.00 24.36 ? 210 VAL A CA 1 ATOM 1626 C C . VAL A 1 210 ? 5.394 33.889 28.986 1.00 29.73 ? 210 VAL A C 1 ATOM 1627 O O . VAL A 1 210 ? 6.415 34.307 29.543 1.00 31.78 ? 210 VAL A O 1 ATOM 1628 C CB . VAL A 1 210 ? 4.946 31.922 30.499 1.00 25.52 ? 210 VAL A CB 1 ATOM 1629 C CG1 . VAL A 1 210 ? 4.047 32.821 31.331 1.00 30.07 ? 210 VAL A CG1 1 ATOM 1630 C CG2 . VAL A 1 210 ? 4.443 30.492 30.550 1.00 27.49 ? 210 VAL A CG2 1 ATOM 1631 N N . ILE A 1 211 ? 4.569 34.667 28.299 1.00 27.49 ? 211 ILE A N 1 ATOM 1632 C CA . ILE A 1 211 ? 4.851 36.077 28.112 1.00 28.35 ? 211 ILE A CA 1 ATOM 1633 C C . ILE A 1 211 ? 3.968 36.925 29.014 1.00 30.59 ? 211 ILE A C 1 ATOM 1634 O O . ILE A 1 211 ? 2.739 36.846 28.960 1.00 31.55 ? 211 ILE A O 1 ATOM 1635 C CB . ILE A 1 211 ? 4.733 36.495 26.632 1.00 26.41 ? 211 ILE A CB 1 ATOM 1636 C CG1 . ILE A 1 211 ? 5.746 35.708 25.794 1.00 22.81 ? 211 ILE A CG1 1 ATOM 1637 C CG2 . ILE A 1 211 ? 4.957 38.001 26.481 1.00 25.48 ? 211 ILE A CG2 1 ATOM 1638 C CD1 . ILE A 1 211 ? 5.643 35.923 24.305 1.00 20.77 ? 211 ILE A CD1 1 ATOM 1639 N N . THR A 1 212 ? 4.622 37.716 29.857 1.00 27.87 ? 212 THR A N 1 ATOM 1640 C CA . THR A 1 212 ? 3.948 38.623 30.771 1.00 26.50 ? 212 THR A CA 1 ATOM 1641 C C . THR A 1 212 ? 3.969 40.023 30.165 1.00 29.65 ? 212 THR A C 1 ATOM 1642 O O . THR A 1 212 ? 5.001 40.479 29.665 1.00 28.76 ? 212 THR A O 1 ATOM 1643 C CB . THR A 1 212 ? 4.627 38.604 32.172 1.00 29.09 ? 212 THR A CB 1 ATOM 1644 O OG1 . THR A 1 212 ? 4.442 37.318 32.777 1.00 31.55 ? 212 THR A OG1 1 ATOM 1645 C CG2 . THR A 1 212 ? 4.041 39.665 33.099 1.00 40.67 ? 212 THR A CG2 1 ATOM 1646 N N . VAL A 1 213 ? 2.820 40.691 30.192 1.00 30.61 ? 213 VAL A N 1 ATOM 1647 C CA . VAL A 1 213 ? 2.716 42.053 29.681 1.00 26.02 ? 213 VAL A CA 1 ATOM 1648 C C . VAL A 1 213 ? 2.991 43.056 30.802 1.00 25.24 ? 213 VAL A C 1 ATOM 1649 O O . VAL A 1 213 ? 2.230 43.145 31.761 1.00 29.79 ? 213 VAL A O 1 ATOM 1650 C CB . VAL A 1 213 ? 1.338 42.326 29.048 1.00 21.93 ? 213 VAL A CB 1 ATOM 1651 C CG1 . VAL A 1 213 ? 1.375 43.614 28.242 1.00 32.44 ? 213 VAL A CG1 1 ATOM 1652 C CG2 . VAL A 1 213 ? 0.913 41.168 28.167 1.00 17.61 ? 213 VAL A CG2 1 ATOM 1653 N N . THR A 1 214 ? 4.084 43.803 30.673 1.00 24.17 ? 214 THR A N 1 ATOM 1654 C CA . THR A 1 214 ? 4.492 44.763 31.701 1.00 30.51 ? 214 THR A CA 1 ATOM 1655 C C . THR A 1 214 ? 3.767 46.101 31.567 1.00 33.35 ? 214 THR A C 1 ATOM 1656 O O . THR A 1 214 ? 3.543 46.585 30.457 1.00 33.89 ? 214 THR A O 1 ATOM 1657 C CB . THR A 1 214 ? 6.015 45.018 31.685 1.00 36.68 ? 214 THR A CB 1 ATOM 1658 O OG1 . THR A 1 214 ? 6.402 45.570 30.420 1.00 37.19 ? 214 THR A OG1 1 ATOM 1659 C CG2 . THR A 1 214 ? 6.790 43.730 31.946 1.00 31.02 ? 214 THR A CG2 1 ATOM 1660 N N . ASP A 1 215 ? 3.438 46.697 32.712 1.00 33.04 ? 215 ASP A N 1 ATOM 1661 C CA . ASP A 1 215 ? 2.629 47.917 32.800 1.00 32.39 ? 215 ASP A CA 1 ATOM 1662 C C . ASP A 1 215 ? 3.283 49.185 32.229 1.00 32.70 ? 215 ASP A C 1 ATOM 1663 O O . ASP A 1 215 ? 4.511 49.307 32.191 1.00 30.39 ? 215 ASP A O 1 ATOM 1664 C CB . ASP A 1 215 ? 2.241 48.153 34.265 1.00 37.66 ? 215 ASP A CB 1 ATOM 1665 C CG . ASP A 1 215 ? 1.245 49.286 34.440 1.00 39.73 ? 215 ASP A CG 1 ATOM 1666 O OD1 . ASP A 1 215 ? 1.433 50.089 35.380 1.00 44.14 ? 215 ASP A OD1 1 ATOM 1667 O OD2 . ASP A 1 215 ? 0.282 49.378 33.645 1.00 33.80 ? 215 ASP A OD2 1 ATOM 1668 N N . VAL A 1 216 ? 2.432 50.110 31.776 1.00 32.93 ? 216 VAL A N 1 ATOM 1669 C CA . VAL A 1 216 ? 2.820 51.461 31.356 1.00 29.99 ? 216 VAL A CA 1 ATOM 1670 C C . VAL A 1 216 ? 1.771 52.431 31.910 1.00 31.75 ? 216 VAL A C 1 ATOM 1671 O O . VAL A 1 216 ? 0.660 52.012 32.246 1.00 28.18 ? 216 VAL A O 1 ATOM 1672 C CB . VAL A 1 216 ? 2.893 51.596 29.806 1.00 25.39 ? 216 VAL A CB 1 ATOM 1673 C CG1 . VAL A 1 216 ? 3.450 52.951 29.394 1.00 25.81 ? 216 VAL A CG1 1 ATOM 1674 C CG2 . VAL A 1 216 ? 3.752 50.508 29.202 1.00 28.87 ? 216 VAL A CG2 1 ATOM 1675 N N . ASN A 1 217 ? 2.121 53.715 32.014 1.00 33.65 ? 217 ASN A N 1 ATOM 1676 C CA . ASN A 1 217 ? 1.170 54.740 32.456 1.00 31.97 ? 217 ASN A CA 1 ATOM 1677 C C . ASN A 1 217 ? 0.214 55.166 31.358 1.00 31.76 ? 217 ASN A C 1 ATOM 1678 O O . ASN A 1 217 ? 0.509 56.082 30.591 1.00 32.02 ? 217 ASN A O 1 ATOM 1679 C CB . ASN A 1 217 ? 1.881 55.975 33.018 1.00 34.78 ? 217 ASN A CB 1 ATOM 1680 C CG . ASN A 1 217 ? 0.921 56.940 33.722 1.00 39.97 ? 217 ASN A CG 1 ATOM 1681 O OD1 . ASN A 1 217 ? -0.179 56.564 34.139 1.00 37.89 ? 217 ASN A OD1 1 ATOM 1682 N ND2 . ASN A 1 217 ? 1.345 58.190 33.860 1.00 42.87 ? 217 ASN A ND2 1 ATOM 1683 N N . ASP A 1 218 ? -0.937 54.505 31.304 1.00 32.57 ? 218 ASP A N 1 ATOM 1684 C CA . ASP A 1 218 ? -1.944 54.786 30.289 1.00 32.96 ? 218 ASP A CA 1 ATOM 1685 C C . ASP A 1 218 ? -3.329 55.039 30.888 1.00 32.66 ? 218 ASP A C 1 ATOM 1686 O O . ASP A 1 218 ? -4.293 55.278 30.162 1.00 38.59 ? 218 ASP A O 1 ATOM 1687 C CB . ASP A 1 218 ? -1.987 53.665 29.243 1.00 31.04 ? 218 ASP A CB 1 ATOM 1688 C CG . ASP A 1 218 ? -2.135 52.282 29.857 1.00 31.01 ? 218 ASP A CG 1 ATOM 1689 O OD1 . ASP A 1 218 ? -2.324 51.317 29.091 1.00 29.64 ? 218 ASP A OD1 1 ATOM 1690 O OD2 . ASP A 1 218 ? -2.061 52.139 31.095 1.00 31.16 ? 218 ASP A OD2 1 ATOM 1691 N N . ASN A 1 219 ? -3.426 54.978 32.210 1.00 28.96 ? 219 ASN A N 1 ATOM 1692 C CA . ASN A 1 219 ? -4.641 55.403 32.889 1.00 36.66 ? 219 ASN A CA 1 ATOM 1693 C C . ASN A 1 219 ? -4.371 56.540 33.861 1.00 42.00 ? 219 ASN A C 1 ATOM 1694 O O . ASN A 1 219 ? -3.486 56.429 34.713 1.00 35.06 ? 219 ASN A O 1 ATOM 1695 C CB . ASN A 1 219 ? -5.322 54.244 33.606 1.00 37.53 ? 219 ASN A CB 1 ATOM 1696 C CG . ASN A 1 219 ? -6.090 53.361 32.666 1.00 36.92 ? 219 ASN A CG 1 ATOM 1697 O OD1 . ASN A 1 219 ? -5.504 52.602 31.899 1.00 41.55 ? 219 ASN A OD1 1 ATOM 1698 N ND2 . ASN A 1 219 ? -7.414 53.448 32.718 1.00 40.31 ? 219 ASN A ND2 1 ATOM 1699 N N . PRO A 1 220 ? -5.138 57.638 33.738 1.00 41.29 ? 220 PRO A N 1 ATOM 1700 C CA . PRO A 1 220 ? -4.926 58.788 34.588 1.00 34.54 ? 220 PRO A CA 1 ATOM 1701 C C . PRO A 1 220 ? -5.583 58.563 35.943 1.00 37.80 ? 220 PRO A C 1 ATOM 1702 O O . PRO A 1 220 ? -6.498 57.745 36.048 1.00 38.82 ? 220 PRO A O 1 ATOM 1703 C CB . PRO A 1 220 ? -5.634 59.921 33.833 1.00 36.46 ? 220 PRO A CB 1 ATOM 1704 C CG . PRO A 1 220 ? -6.191 59.314 32.577 1.00 36.78 ? 220 PRO A CG 1 ATOM 1705 C CD . PRO A 1 220 ? -6.259 57.855 32.812 1.00 42.15 ? 220 PRO A CD 1 ATOM 1706 N N . PRO A 1 221 ? -5.107 59.270 36.982 1.00 36.44 ? 221 PRO A N 1 ATOM 1707 C CA . PRO A 1 221 ? -5.767 59.204 38.274 1.00 35.09 ? 221 PRO A CA 1 ATOM 1708 C C . PRO A 1 221 ? -7.123 59.894 38.196 1.00 38.89 ? 221 PRO A C 1 ATOM 1709 O O . PRO A 1 221 ? -7.231 60.978 37.624 1.00 37.90 ? 221 PRO A O 1 ATOM 1710 C CB . PRO A 1 221 ? -4.823 59.993 39.187 1.00 41.42 ? 221 PRO A CB 1 ATOM 1711 C CG . PRO A 1 221 ? -3.541 60.116 38.432 1.00 36.09 ? 221 PRO A CG 1 ATOM 1712 C CD . PRO A 1 221 ? -3.935 60.160 37.014 1.00 37.01 ? 221 PRO A CD 1 ATOM 1713 N N . GLU A 1 222 ? -8.148 59.260 38.755 1.00 43.56 ? 222 GLU A N 1 ATOM 1714 C CA . GLU A 1 222 ? -9.503 59.810 38.735 1.00 45.46 ? 222 GLU A CA 1 ATOM 1715 C C . GLU A 1 222 ? -10.096 59.901 40.138 1.00 48.30 ? 222 GLU A C 1 ATOM 1716 O O . GLU A 1 222 ? -10.195 58.890 40.841 1.00 47.68 ? 222 GLU A O 1 ATOM 1717 C CB . GLU A 1 222 ? -10.421 58.953 37.856 1.00 47.92 ? 222 GLU A CB 1 ATOM 1718 C CG . GLU A 1 222 ? -10.146 59.029 36.362 1.00 47.00 ? 222 GLU A CG 1 ATOM 1719 C CD . GLU A 1 222 ? -11.289 58.468 35.527 1.00 50.94 ? 222 GLU A CD 1 ATOM 1720 O OE1 . GLU A 1 222 ? -11.888 57.440 35.916 1.00 44.86 ? 222 GLU A OE1 1 ATOM 1721 O OE2 . GLU A 1 222 ? -11.588 59.060 34.471 1.00 59.88 ? 222 GLU A OE2 1 ATOM 1722 N N . PHE A 1 223 ? -10.503 61.108 40.530 1.00 44.90 ? 223 PHE A N 1 ATOM 1723 C CA . PHE A 1 223 ? -11.120 61.337 41.839 1.00 45.61 ? 223 PHE A CA 1 ATOM 1724 C C . PHE A 1 223 ? -12.465 60.627 41.971 1.00 45.97 ? 223 PHE A C 1 ATOM 1725 O O . PHE A 1 223 ? -13.287 60.674 41.055 1.00 46.42 ? 223 PHE A O 1 ATOM 1726 C CB . PHE A 1 223 ? -11.311 62.831 42.085 1.00 41.51 ? 223 PHE A CB 1 ATOM 1727 C CG . PHE A 1 223 ? -10.031 63.596 42.222 1.00 37.83 ? 223 PHE A CG 1 ATOM 1728 C CD1 . PHE A 1 223 ? -9.375 63.664 43.442 1.00 43.95 ? 223 PHE A CD1 1 ATOM 1729 C CD2 . PHE A 1 223 ? -9.496 64.275 41.138 1.00 41.32 ? 223 PHE A CD2 1 ATOM 1730 C CE1 . PHE A 1 223 ? -8.193 64.385 43.574 1.00 45.05 ? 223 PHE A CE1 1 ATOM 1731 C CE2 . PHE A 1 223 ? -8.317 64.998 41.264 1.00 43.93 ? 223 PHE A CE2 1 ATOM 1732 C CZ . PHE A 1 223 ? -7.663 65.052 42.482 1.00 39.28 ? 223 PHE A CZ 1 ATOM 1733 N N . THR A 1 224 ? -12.683 59.987 43.119 1.00 43.55 ? 224 THR A N 1 ATOM 1734 C CA . THR A 1 224 ? -13.915 59.240 43.392 1.00 53.22 ? 224 THR A CA 1 ATOM 1735 C C . THR A 1 224 ? -15.160 60.132 43.357 1.00 58.09 ? 224 THR A C 1 ATOM 1736 O O . THR A 1 224 ? -16.236 59.693 42.935 1.00 63.58 ? 224 THR A O 1 ATOM 1737 C CB . THR A 1 224 ? -13.834 58.501 44.746 1.00 56.85 ? 224 THR A CB 1 ATOM 1738 O OG1 . THR A 1 224 ? -12.600 57.777 44.813 1.00 57.80 ? 224 THR A OG1 1 ATOM 1739 C CG2 . THR A 1 224 ? -15.006 57.520 44.920 1.00 55.28 ? 224 THR A CG2 1 ATOM 1740 N N . ALA A 1 225 ? -15.003 61.377 43.798 1.00 53.72 ? 225 ALA A N 1 ATOM 1741 C CA . ALA A 1 225 ? -16.079 62.360 43.750 1.00 51.79 ? 225 ALA A CA 1 ATOM 1742 C C . ALA A 1 225 ? -15.608 63.649 43.095 1.00 48.42 ? 225 ALA A C 1 ATOM 1743 O O . ALA A 1 225 ? -14.417 63.968 43.123 1.00 42.83 ? 225 ALA A O 1 ATOM 1744 C CB . ALA A 1 225 ? -16.606 62.633 45.146 1.00 65.77 ? 225 ALA A CB 1 ATOM 1745 N N . MET A 1 226 ? -16.551 64.383 42.508 1.00 59.20 ? 226 MET A N 1 ATOM 1746 C CA . MET A 1 226 ? -16.258 65.661 41.859 1.00 69.21 ? 226 MET A CA 1 ATOM 1747 C C . MET A 1 226 ? -15.861 66.743 42.877 1.00 71.46 ? 226 MET A C 1 ATOM 1748 O O . MET A 1 226 ? -15.026 67.606 42.577 1.00 68.58 ? 226 MET A O 1 ATOM 1749 C CB . MET A 1 226 ? -17.451 66.123 41.011 1.00 74.90 ? 226 MET A CB 1 ATOM 1750 C CG . MET A 1 226 ? -17.106 67.170 39.948 1.00 86.68 ? 226 MET A CG 1 ATOM 1751 S SD . MET A 1 226 ? -18.543 68.111 39.367 1.00 93.30 ? 226 MET A SD 1 ATOM 1752 C CE . MET A 1 226 ? -17.782 69.252 38.209 1.00 93.14 ? 226 MET A CE 1 ATOM 1753 N N . THR A 1 227 ? -16.450 66.684 44.074 1.00 66.87 ? 227 THR A N 1 ATOM 1754 C CA . THR A 1 227 ? -16.168 67.659 45.135 1.00 66.09 ? 227 THR A CA 1 ATOM 1755 C C . THR A 1 227 ? -15.932 67.035 46.514 1.00 64.34 ? 227 THR A C 1 ATOM 1756 O O . THR A 1 227 ? -16.578 66.048 46.882 1.00 60.02 ? 227 THR A O 1 ATOM 1757 C CB . THR A 1 227 ? -17.275 68.739 45.238 1.00 72.49 ? 227 THR A CB 1 ATOM 1758 O OG1 . THR A 1 227 ? -18.539 68.173 44.865 1.00 75.32 ? 227 THR A OG1 1 ATOM 1759 C CG2 . THR A 1 227 ? -16.969 69.912 44.317 1.00 68.63 ? 227 THR A CG2 1 ATOM 1760 N N . PHE A 1 228 ? -14.999 67.624 47.263 1.00 63.07 ? 228 PHE A N 1 ATOM 1761 C CA . PHE A 1 228 ? -14.641 67.168 48.611 1.00 65.18 ? 228 PHE A CA 1 ATOM 1762 C C . PHE A 1 228 ? -14.852 68.283 49.637 1.00 72.15 ? 228 PHE A C 1 ATOM 1763 O O . PHE A 1 228 ? -14.901 69.463 49.275 1.00 67.42 ? 228 PHE A O 1 ATOM 1764 C CB . PHE A 1 228 ? -13.182 66.706 48.655 1.00 61.91 ? 228 PHE A CB 1 ATOM 1765 C CG . PHE A 1 228 ? -12.884 65.529 47.770 1.00 63.88 ? 228 PHE A CG 1 ATOM 1766 C CD1 . PHE A 1 228 ? -13.149 64.234 48.202 1.00 58.74 ? 228 PHE A CD1 1 ATOM 1767 C CD2 . PHE A 1 228 ? -12.323 65.713 46.510 1.00 61.60 ? 228 PHE A CD2 1 ATOM 1768 C CE1 . PHE A 1 228 ? -12.870 63.146 47.390 1.00 55.53 ? 228 PHE A CE1 1 ATOM 1769 C CE2 . PHE A 1 228 ? -12.040 64.627 45.692 1.00 45.70 ? 228 PHE A CE2 1 ATOM 1770 C CZ . PHE A 1 228 ? -12.314 63.342 46.133 1.00 50.93 ? 228 PHE A CZ 1 ATOM 1771 N N . TYR A 1 229 ? -14.958 67.904 50.913 1.00 72.49 ? 229 TYR A N 1 ATOM 1772 C CA . TYR A 1 229 ? -15.251 68.859 51.991 1.00 64.05 ? 229 TYR A CA 1 ATOM 1773 C C . TYR A 1 229 ? -14.356 68.691 53.224 1.00 68.82 ? 229 TYR A C 1 ATOM 1774 O O . TYR A 1 229 ? -14.083 67.568 53.657 1.00 71.69 ? 229 TYR A O 1 ATOM 1775 C CB . TYR A 1 229 ? -16.731 68.776 52.392 1.00 59.55 ? 229 TYR A CB 1 ATOM 1776 C CG . TYR A 1 229 ? -17.679 68.875 51.219 1.00 59.92 ? 229 TYR A CG 1 ATOM 1777 C CD1 . TYR A 1 229 ? -17.965 70.108 50.630 1.00 67.23 ? 229 TYR A CD1 1 ATOM 1778 C CD2 . TYR A 1 229 ? -18.279 67.735 50.685 1.00 62.57 ? 229 TYR A CD2 1 ATOM 1779 C CE1 . TYR A 1 229 ? -18.831 70.203 49.543 1.00 69.01 ? 229 TYR A CE1 1 ATOM 1780 C CE2 . TYR A 1 229 ? -19.147 67.818 49.596 1.00 68.32 ? 229 TYR A CE2 1 ATOM 1781 C CZ . TYR A 1 229 ? -19.418 69.055 49.030 1.00 69.86 ? 229 TYR A CZ 1 ATOM 1782 O OH . TYR A 1 229 ? -20.273 69.148 47.955 1.00 61.79 ? 229 TYR A OH 1 ATOM 1783 N N . GLY A 1 230 ? -13.914 69.819 53.783 1.00 74.02 ? 230 GLY A N 1 ATOM 1784 C CA . GLY A 1 230 ? -13.059 69.842 54.979 1.00 77.26 ? 230 GLY A CA 1 ATOM 1785 C C . GLY A 1 230 ? -13.286 71.042 55.891 1.00 79.23 ? 230 GLY A C 1 ATOM 1786 O O . GLY A 1 230 ? -13.972 72.000 55.515 1.00 77.43 ? 230 GLY A O 1 ATOM 1787 N N . GLU A 1 231 ? -12.703 70.988 57.090 1.00 77.58 ? 231 GLU A N 1 ATOM 1788 C CA . GLU A 1 231 ? -12.876 72.035 58.105 1.00 71.84 ? 231 GLU A CA 1 ATOM 1789 C C . GLU A 1 231 ? -11.582 72.367 58.838 1.00 71.54 ? 231 GLU A C 1 ATOM 1790 O O . GLU A 1 231 ? -10.832 71.466 59.214 1.00 76.56 ? 231 GLU A O 1 ATOM 1791 C CB . GLU A 1 231 ? -13.930 71.617 59.128 1.00 76.57 ? 231 GLU A CB 1 ATOM 1792 C CG . GLU A 1 231 ? -15.362 71.797 58.661 1.00 82.69 ? 231 GLU A CG 1 ATOM 1793 C CD . GLU A 1 231 ? -16.377 71.298 59.671 1.00 85.88 ? 231 GLU A CD 1 ATOM 1794 O OE1 . GLU A 1 231 ? -15.970 70.724 60.707 1.00 76.42 ? 231 GLU A OE1 1 ATOM 1795 O OE2 . GLU A 1 231 ? -17.589 71.478 59.422 1.00 85.84 ? 231 GLU A OE2 1 ATOM 1796 N N . VAL A 1 232 ? -11.335 73.659 59.056 1.00 69.34 ? 232 VAL A N 1 ATOM 1797 C CA . VAL A 1 232 ? -10.126 74.101 59.768 1.00 75.09 ? 232 VAL A CA 1 ATOM 1798 C C . VAL A 1 232 ? -10.349 75.186 60.832 1.00 79.47 ? 232 VAL A C 1 ATOM 1799 O O . VAL A 1 232 ? -11.091 76.146 60.600 1.00 80.33 ? 232 VAL A O 1 ATOM 1800 C CB . VAL A 1 232 ? -9.003 74.572 58.803 1.00 66.96 ? 232 VAL A CB 1 ATOM 1801 C CG1 . VAL A 1 232 ? -8.388 73.391 58.083 1.00 68.12 ? 232 VAL A CG1 1 ATOM 1802 C CG2 . VAL A 1 232 ? -9.514 75.625 57.818 1.00 64.46 ? 232 VAL A CG2 1 ATOM 1803 N N . PRO A 1 233 ? -9.710 75.025 62.009 1.00 77.55 ? 233 PRO A N 1 ATOM 1804 C CA . PRO A 1 233 ? -9.631 76.098 62.995 1.00 80.44 ? 233 PRO A CA 1 ATOM 1805 C C . PRO A 1 233 ? -8.645 77.191 62.592 1.00 74.53 ? 233 PRO A C 1 ATOM 1806 O O . PRO A 1 233 ? -7.755 76.971 61.764 1.00 61.49 ? 233 PRO A O 1 ATOM 1807 C CB . PRO A 1 233 ? -9.121 75.386 64.260 1.00 76.69 ? 233 PRO A CB 1 ATOM 1808 C CG . PRO A 1 233 ? -9.227 73.925 63.977 1.00 74.16 ? 233 PRO A CG 1 ATOM 1809 C CD . PRO A 1 233 ? -9.060 73.801 62.504 1.00 76.41 ? 233 PRO A CD 1 ATOM 1810 N N . GLU A 1 234 ? -8.825 78.359 63.196 1.00 72.04 ? 234 GLU A N 1 ATOM 1811 C CA . GLU A 1 234 ? -7.947 79.504 63.029 1.00 65.22 ? 234 GLU A CA 1 ATOM 1812 C C . GLU A 1 234 ? -6.594 79.215 63.666 1.00 69.67 ? 234 GLU A C 1 ATOM 1813 O O . GLU A 1 234 ? -6.508 78.439 64.621 1.00 78.38 ? 234 GLU A O 1 ATOM 1814 C CB . GLU A 1 234 ? -8.575 80.694 63.741 1.00 74.02 ? 234 GLU A CB 1 ATOM 1815 C CG . GLU A 1 234 ? -8.683 81.961 62.927 1.00 77.72 ? 234 GLU A CG 1 ATOM 1816 C CD . GLU A 1 234 ? -9.704 82.924 63.509 1.00 77.31 ? 234 GLU A CD 1 ATOM 1817 O OE1 . GLU A 1 234 ? -9.456 84.147 63.473 1.00 72.95 ? 234 GLU A OE1 1 ATOM 1818 O OE2 . GLU A 1 234 ? -10.755 82.462 64.010 1.00 79.10 ? 234 GLU A OE2 1 ATOM 1819 N N . ASN A 1 235 ? -5.549 79.843 63.129 1.00 67.91 ? 235 ASN A N 1 ATOM 1820 C CA . ASN A 1 235 ? -4.190 79.806 63.702 1.00 72.72 ? 235 ASN A CA 1 ATOM 1821 C C . ASN A 1 235 ? -3.645 78.407 64.032 1.00 82.16 ? 235 ASN A C 1 ATOM 1822 O O . ASN A 1 235 ? -3.157 78.159 65.142 1.00 77.97 ? 235 ASN A O 1 ATOM 1823 C CB . ASN A 1 235 ? -4.094 80.729 64.927 1.00 68.40 ? 235 ASN A CB 1 ATOM 1824 C CG . ASN A 1 235 ? -4.678 82.107 64.671 1.00 74.74 ? 235 ASN A CG 1 ATOM 1825 O OD1 . ASN A 1 235 ? -5.717 82.464 65.229 1.00 73.22 ? 235 ASN A OD1 1 ATOM 1826 N ND2 . ASN A 1 235 ? -4.018 82.884 63.816 1.00 70.64 ? 235 ASN A ND2 1 ATOM 1827 N N . ARG A 1 236 ? -3.741 77.502 63.060 1.00 79.05 ? 236 ARG A N 1 ATOM 1828 C CA . ARG A 1 236 ? -3.185 76.156 63.184 1.00 69.80 ? 236 ARG A CA 1 ATOM 1829 C C . ARG A 1 236 ? -2.207 75.914 62.037 1.00 64.74 ? 236 ARG A C 1 ATOM 1830 O O . ARG A 1 236 ? -2.361 76.496 60.961 1.00 60.89 ? 236 ARG A O 1 ATOM 1831 C CB . ARG A 1 236 ? -4.299 75.104 63.188 1.00 71.91 ? 236 ARG A CB 1 ATOM 1832 C CG . ARG A 1 236 ? -5.328 75.240 64.324 1.00 67.50 ? 236 ARG A CG 1 ATOM 1833 C CD . ARG A 1 236 ? -4.729 75.001 65.716 1.00 69.11 ? 236 ARG A CD 1 ATOM 1834 N NE . ARG A 1 236 ? -4.068 73.699 65.843 1.00 79.57 ? 236 ARG A NE 1 ATOM 1835 C CZ . ARG A 1 236 ? -4.671 72.567 66.207 1.00 77.77 ? 236 ARG A CZ 1 ATOM 1836 N NH1 . ARG A 1 236 ? -5.971 72.548 66.486 1.00 73.75 ? 236 ARG A NH1 1 ATOM 1837 N NH2 . ARG A 1 236 ? -3.969 71.443 66.290 1.00 62.45 ? 236 ARG A NH2 1 ATOM 1838 N N . VAL A 1 237 ? -1.207 75.063 62.263 1.00 65.17 ? 237 VAL A N 1 ATOM 1839 C CA . VAL A 1 237 ? -0.078 74.949 61.331 1.00 67.09 ? 237 VAL A CA 1 ATOM 1840 C C . VAL A 1 237 ? 0.340 73.504 60.987 1.00 71.00 ? 237 VAL A C 1 ATOM 1841 O O . VAL A 1 237 ? 1.239 73.290 60.163 1.00 73.59 ? 237 VAL A O 1 ATOM 1842 C CB . VAL A 1 237 ? 1.140 75.802 61.826 1.00 68.12 ? 237 VAL A CB 1 ATOM 1843 C CG1 . VAL A 1 237 ? 2.044 74.998 62.764 1.00 75.23 ? 237 VAL A CG1 1 ATOM 1844 C CG2 . VAL A 1 237 ? 1.932 76.369 60.654 1.00 55.36 ? 237 VAL A CG2 1 ATOM 1845 N N . ASP A 1 238 ? -0.310 72.518 61.603 1.00 60.14 ? 238 ASP A N 1 ATOM 1846 C CA . ASP A 1 238 ? -0.067 71.119 61.250 1.00 60.21 ? 238 ASP A CA 1 ATOM 1847 C C . ASP A 1 238 ? -1.315 70.265 61.463 1.00 58.08 ? 238 ASP A C 1 ATOM 1848 O O . ASP A 1 238 ? -1.334 69.369 62.307 1.00 62.59 ? 238 ASP A O 1 ATOM 1849 C CB . ASP A 1 238 ? 1.131 70.555 62.027 1.00 72.45 ? 238 ASP A CB 1 ATOM 1850 C CG . ASP A 1 238 ? 1.899 69.497 61.238 1.00 81.42 ? 238 ASP A CG 1 ATOM 1851 O OD1 . ASP A 1 238 ? 2.580 69.864 60.253 1.00 74.26 ? 238 ASP A OD1 1 ATOM 1852 O OD2 . ASP A 1 238 ? 1.836 68.302 61.609 1.00 77.07 ? 238 ASP A OD2 1 ATOM 1853 N N . VAL A 1 239 ? -2.360 70.554 60.694 1.00 54.16 ? 239 VAL A N 1 ATOM 1854 C CA . VAL A 1 239 ? -3.621 69.821 60.795 1.00 56.46 ? 239 VAL A CA 1 ATOM 1855 C C . VAL A 1 239 ? -4.115 69.398 59.413 1.00 62.27 ? 239 VAL A C 1 ATOM 1856 O O . VAL A 1 239 ? -4.024 70.162 58.451 1.00 72.44 ? 239 VAL A O 1 ATOM 1857 C CB . VAL A 1 239 ? -4.719 70.655 61.503 1.00 61.51 ? 239 VAL A CB 1 ATOM 1858 C CG1 . VAL A 1 239 ? -5.969 69.811 61.754 1.00 61.42 ? 239 VAL A CG1 1 ATOM 1859 C CG2 . VAL A 1 239 ? -4.203 71.233 62.816 1.00 68.50 ? 239 VAL A CG2 1 ATOM 1860 N N . ILE A 1 240 ? -4.635 68.177 59.324 1.00 60.20 ? 240 ILE A N 1 ATOM 1861 C CA . ILE A 1 240 ? -5.189 67.655 58.077 1.00 62.46 ? 240 ILE A CA 1 ATOM 1862 C C . ILE A 1 240 ? -6.562 68.265 57.800 1.00 60.60 ? 240 ILE A C 1 ATOM 1863 O O . ILE A 1 240 ? -7.431 68.295 58.676 1.00 59.55 ? 240 ILE A O 1 ATOM 1864 C CB . ILE A 1 240 ? -5.233 66.101 58.081 1.00 71.80 ? 240 ILE A CB 1 ATOM 1865 C CG1 . ILE A 1 240 ? -3.857 65.542 57.698 1.00 68.73 ? 240 ILE A CG1 1 ATOM 1866 C CG2 . ILE A 1 240 ? -6.317 65.563 57.137 1.00 63.83 ? 240 ILE A CG2 1 ATOM 1867 C CD1 . ILE A 1 240 ? -3.623 64.095 58.116 1.00 73.82 ? 240 ILE A CD1 1 ATOM 1868 N N . VAL A 1 241 ? -6.735 68.753 56.574 1.00 61.32 ? 241 VAL A N 1 ATOM 1869 C CA . VAL A 1 241 ? -7.973 69.394 56.145 1.00 62.57 ? 241 VAL A CA 1 ATOM 1870 C C . VAL A 1 241 ? -8.950 68.381 55.535 1.00 68.11 ? 241 VAL A C 1 ATOM 1871 O O . VAL A 1 241 ? -10.066 68.215 56.036 1.00 61.24 ? 241 VAL A O 1 ATOM 1872 C CB . VAL A 1 241 ? -7.696 70.524 55.133 1.00 62.52 ? 241 VAL A CB 1 ATOM 1873 C CG1 . VAL A 1 241 ? -8.912 71.432 55.004 1.00 66.46 ? 241 VAL A CG1 1 ATOM 1874 C CG2 . VAL A 1 241 ? -6.471 71.326 55.547 1.00 57.50 ? 241 VAL A CG2 1 ATOM 1875 N N . ALA A 1 242 ? -8.524 67.718 54.455 1.00 70.47 ? 242 ALA A N 1 ATOM 1876 C CA . ALA A 1 242 ? -9.338 66.700 53.776 1.00 66.32 ? 242 ALA A CA 1 ATOM 1877 C C . ALA A 1 242 ? -8.493 65.586 53.150 1.00 67.25 ? 242 ALA A C 1 ATOM 1878 O O . ALA A 1 242 ? -7.316 65.790 52.830 1.00 58.40 ? 242 ALA A O 1 ATOM 1879 C CB . ALA A 1 242 ? -10.228 67.346 52.719 1.00 59.21 ? 242 ALA A CB 1 ATOM 1880 N N . ASN A 1 243 ? -9.110 64.413 52.988 1.00 76.66 ? 243 ASN A N 1 ATOM 1881 C CA . ASN A 1 243 ? -8.498 63.269 52.302 1.00 68.44 ? 243 ASN A CA 1 ATOM 1882 C C . ASN A 1 243 ? -9.065 63.107 50.897 1.00 60.14 ? 243 ASN A C 1 ATOM 1883 O O . ASN A 1 243 ? -10.209 62.681 50.723 1.00 59.70 ? 243 ASN A O 1 ATOM 1884 C CB . ASN A 1 243 ? -8.716 61.970 53.088 1.00 72.31 ? 243 ASN A CB 1 ATOM 1885 C CG . ASN A 1 243 ? -8.202 62.049 54.518 1.00 87.52 ? 243 ASN A CG 1 ATOM 1886 O OD1 . ASN A 1 243 ? -7.214 62.735 54.799 1.00 88.41 ? 243 ASN A OD1 1 ATOM 1887 N ND2 . ASN A 1 243 ? -8.878 61.347 55.434 1.00 96.36 ? 243 ASN A ND2 1 ATOM 1888 N N . LEU A 1 244 ? -8.262 63.453 49.899 1.00 55.44 ? 244 LEU A N 1 ATOM 1889 C CA . LEU A 1 244 ? -8.691 63.365 48.509 1.00 53.98 ? 244 LEU A CA 1 ATOM 1890 C C . LEU A 1 244 ? -8.520 61.944 47.996 1.00 50.49 ? 244 LEU A C 1 ATOM 1891 O O . LEU A 1 244 ? -7.411 61.405 47.975 1.00 47.48 ? 244 LEU A O 1 ATOM 1892 C CB . LEU A 1 244 ? -7.909 64.351 47.643 1.00 51.60 ? 244 LEU A CB 1 ATOM 1893 C CG . LEU A 1 244 ? -7.824 65.794 48.143 1.00 47.32 ? 244 LEU A CG 1 ATOM 1894 C CD1 . LEU A 1 244 ? -6.966 66.614 47.209 1.00 45.09 ? 244 LEU A CD1 1 ATOM 1895 C CD2 . LEU A 1 244 ? -9.207 66.404 48.282 1.00 55.58 ? 244 LEU A CD2 1 ATOM 1896 N N . THR A 1 245 ? -9.630 61.348 47.578 1.00 44.43 ? 245 THR A N 1 ATOM 1897 C CA . THR A 1 245 ? -9.662 59.928 47.255 1.00 45.92 ? 245 THR A CA 1 ATOM 1898 C C . THR A 1 245 ? -9.728 59.660 45.739 1.00 53.38 ? 245 THR A C 1 ATOM 1899 O O . THR A 1 245 ? -10.639 60.136 45.050 1.00 47.79 ? 245 THR A O 1 ATOM 1900 C CB . THR A 1 245 ? -10.776 59.199 48.067 1.00 42.82 ? 245 THR A CB 1 ATOM 1901 O OG1 . THR A 1 245 ? -10.699 57.787 47.851 1.00 56.86 ? 245 THR A OG1 1 ATOM 1902 C CG2 . THR A 1 245 ? -12.172 59.708 47.712 1.00 42.64 ? 245 THR A CG2 1 ATOM 1903 N N . VAL A 1 246 ? -8.741 58.910 45.236 1.00 56.97 ? 246 VAL A N 1 ATOM 1904 C CA . VAL A 1 246 ? -8.566 58.665 43.790 1.00 48.14 ? 246 VAL A CA 1 ATOM 1905 C C . VAL A 1 246 ? -8.534 57.182 43.396 1.00 45.33 ? 246 VAL A C 1 ATOM 1906 O O . VAL A 1 246 ? -8.271 56.313 44.232 1.00 46.27 ? 246 VAL A O 1 ATOM 1907 C CB . VAL A 1 246 ? -7.272 59.332 43.236 1.00 39.74 ? 246 VAL A CB 1 ATOM 1908 C CG1 . VAL A 1 246 ? -7.321 60.834 43.399 1.00 42.00 ? 246 VAL A CG1 1 ATOM 1909 C CG2 . VAL A 1 246 ? -6.029 58.762 43.902 1.00 43.71 ? 246 VAL A CG2 1 ATOM 1910 N N . THR A 1 247 ? -8.799 56.912 42.116 1.00 42.88 ? 247 THR A N 1 ATOM 1911 C CA . THR A 1 247 ? -8.628 55.580 41.527 1.00 40.16 ? 247 THR A CA 1 ATOM 1912 C C . THR A 1 247 ? -7.724 55.650 40.298 1.00 40.16 ? 247 THR A C 1 ATOM 1913 O O . THR A 1 247 ? -7.906 56.506 39.425 1.00 38.69 ? 247 THR A O 1 ATOM 1914 C CB . THR A 1 247 ? -9.968 54.929 41.109 1.00 33.84 ? 247 THR A CB 1 ATOM 1915 O OG1 . THR A 1 247 ? -10.682 55.815 40.240 1.00 42.79 ? 247 THR A OG1 1 ATOM 1916 C CG2 . THR A 1 247 ? -10.829 54.594 42.321 1.00 36.68 ? 247 THR A CG2 1 ATOM 1917 N N . ASP A 1 248 ? -6.747 54.749 40.248 1.00 39.30 ? 248 ASP A N 1 ATOM 1918 C CA . ASP A 1 248 ? -5.860 54.613 39.102 1.00 32.71 ? 248 ASP A CA 1 ATOM 1919 C C . ASP A 1 248 ? -5.904 53.165 38.644 1.00 35.77 ? 248 ASP A C 1 ATOM 1920 O O . ASP A 1 248 ? -5.711 52.250 39.445 1.00 45.23 ? 248 ASP A O 1 ATOM 1921 C CB . ASP A 1 248 ? -4.435 55.021 39.471 1.00 30.38 ? 248 ASP A CB 1 ATOM 1922 C CG . ASP A 1 248 ? -3.576 55.327 38.256 1.00 36.33 ? 248 ASP A CG 1 ATOM 1923 O OD1 . ASP A 1 248 ? -3.757 54.690 37.196 1.00 36.23 ? 248 ASP A OD1 1 ATOM 1924 O OD2 . ASP A 1 248 ? -2.704 56.215 38.358 1.00 34.50 ? 248 ASP A OD2 1 ATOM 1925 N N . LYS A 1 249 ? -6.169 52.958 37.357 1.00 36.50 ? 249 LYS A N 1 ATOM 1926 C CA . LYS A 1 249 ? -6.391 51.611 36.833 1.00 37.08 ? 249 LYS A CA 1 ATOM 1927 C C . LYS A 1 249 ? -5.099 50.855 36.535 1.00 36.10 ? 249 LYS A C 1 ATOM 1928 O O . LYS A 1 249 ? -5.130 49.642 36.324 1.00 39.69 ? 249 LYS A O 1 ATOM 1929 C CB . LYS A 1 249 ? -7.319 51.633 35.611 1.00 36.35 ? 249 LYS A CB 1 ATOM 1930 C CG . LYS A 1 249 ? -8.745 52.060 35.934 1.00 41.15 ? 249 LYS A CG 1 ATOM 1931 C CD . LYS A 1 249 ? -9.763 51.446 34.988 1.00 44.64 ? 249 LYS A CD 1 ATOM 1932 C CE . LYS A 1 249 ? -11.182 51.780 35.440 1.00 57.97 ? 249 LYS A CE 1 ATOM 1933 N NZ . LYS A 1 249 ? -12.208 50.856 34.876 1.00 58.30 ? 249 LYS A NZ 1 ATOM 1934 N N . ASP A 1 250 ? -3.974 51.569 36.538 1.00 32.46 ? 250 ASP A N 1 ATOM 1935 C CA . ASP A 1 250 ? -2.652 50.960 36.351 1.00 33.83 ? 250 ASP A CA 1 ATOM 1936 C C . ASP A 1 250 ? -2.232 50.105 37.555 1.00 40.05 ? 250 ASP A C 1 ATOM 1937 O O . ASP A 1 250 ? -3.032 49.863 38.467 1.00 41.65 ? 250 ASP A O 1 ATOM 1938 C CB . ASP A 1 250 ? -1.598 52.032 36.053 1.00 32.31 ? 250 ASP A CB 1 ATOM 1939 C CG . ASP A 1 250 ? -1.838 52.744 34.731 1.00 37.46 ? 250 ASP A CG 1 ATOM 1940 O OD1 . ASP A 1 250 ? -2.702 52.302 33.946 1.00 42.16 ? 250 ASP A OD1 1 ATOM 1941 O OD2 . ASP A 1 250 ? -1.158 53.756 34.473 1.00 37.38 ? 250 ASP A OD2 1 ATOM 1942 N N . GLN A 1 251 ? -0.981 49.651 37.560 1.00 37.30 ? 251 GLN A N 1 ATOM 1943 C CA . GLN A 1 251 ? -0.521 48.702 38.572 1.00 40.31 ? 251 GLN A CA 1 ATOM 1944 C C . GLN A 1 251 ? -0.216 49.337 39.927 1.00 40.24 ? 251 GLN A C 1 ATOM 1945 O O . GLN A 1 251 ? 0.645 50.208 40.018 1.00 38.80 ? 251 GLN A O 1 ATOM 1946 C CB . GLN A 1 251 ? 0.697 47.927 38.075 1.00 42.05 ? 251 GLN A CB 1 ATOM 1947 C CG . GLN A 1 251 ? 1.069 46.762 38.977 1.00 42.96 ? 251 GLN A CG 1 ATOM 1948 C CD . GLN A 1 251 ? 2.104 45.853 38.361 1.00 51.81 ? 251 GLN A CD 1 ATOM 1949 O OE1 . GLN A 1 251 ? 2.933 46.285 37.556 1.00 53.84 ? 251 GLN A OE1 1 ATOM 1950 N NE2 . GLN A 1 251 ? 2.064 44.580 38.739 1.00 59.25 ? 251 GLN A NE2 1 ATOM 1951 N N . PRO A 1 252 ? -0.908 48.884 40.991 1.00 38.35 ? 252 PRO A N 1 ATOM 1952 C CA . PRO A 1 252 ? -0.691 49.397 42.337 1.00 32.74 ? 252 PRO A CA 1 ATOM 1953 C C . PRO A 1 252 ? 0.777 49.602 42.684 1.00 32.70 ? 252 PRO A C 1 ATOM 1954 O O . PRO A 1 252 ? 1.618 48.756 42.382 1.00 35.88 ? 252 PRO A O 1 ATOM 1955 C CB . PRO A 1 252 ? -1.298 48.309 43.216 1.00 32.56 ? 252 PRO A CB 1 ATOM 1956 C CG . PRO A 1 252 ? -2.422 47.809 42.416 1.00 37.77 ? 252 PRO A CG 1 ATOM 1957 C CD . PRO A 1 252 ? -1.962 47.854 40.978 1.00 41.83 ? 252 PRO A CD 1 ATOM 1958 N N . HIS A 1 253 ? 1.060 50.755 43.280 1.00 37.04 ? 253 HIS A N 1 ATOM 1959 C CA . HIS A 1 253 ? 2.360 51.092 43.860 1.00 36.82 ? 253 HIS A CA 1 ATOM 1960 C C . HIS A 1 253 ? 3.516 51.180 42.865 1.00 42.49 ? 253 HIS A C 1 ATOM 1961 O O . HIS A 1 253 ? 4.676 51.311 43.264 1.00 47.43 ? 253 HIS A O 1 ATOM 1962 C CB . HIS A 1 253 ? 2.671 50.176 45.045 1.00 34.42 ? 253 HIS A CB 1 ATOM 1963 C CG . HIS A 1 253 ? 1.573 50.142 46.061 1.00 41.22 ? 253 HIS A CG 1 ATOM 1964 N ND1 . HIS A 1 253 ? 1.427 51.111 47.031 1.00 42.72 ? 253 HIS A ND1 1 ATOM 1965 C CD2 . HIS A 1 253 ? 0.545 49.278 46.234 1.00 37.98 ? 253 HIS A CD2 1 ATOM 1966 C CE1 . HIS A 1 253 ? 0.366 50.835 47.768 1.00 43.84 ? 253 HIS A CE1 1 ATOM 1967 N NE2 . HIS A 1 253 ? -0.188 49.729 47.305 1.00 38.62 ? 253 HIS A NE2 1 ATOM 1968 N N . THR A 1 254 ? 3.193 51.126 41.573 1.00 38.71 ? 254 THR A N 1 ATOM 1969 C CA . THR A 1 254 ? 4.138 51.528 40.538 1.00 40.26 ? 254 THR A CA 1 ATOM 1970 C C . THR A 1 254 ? 4.061 53.053 40.415 1.00 34.29 ? 254 THR A C 1 ATOM 1971 O O . THR A 1 254 ? 3.012 53.637 40.687 1.00 33.83 ? 254 THR A O 1 ATOM 1972 C CB . THR A 1 254 ? 3.876 50.812 39.163 1.00 48.26 ? 254 THR A CB 1 ATOM 1973 O OG1 . THR A 1 254 ? 4.899 51.165 38.222 1.00 61.03 ? 254 THR A OG1 1 ATOM 1974 C CG2 . THR A 1 254 ? 2.536 51.194 38.560 1.00 45.11 ? 254 THR A CG2 1 ATOM 1975 N N . PRO A 1 255 ? 5.180 53.707 40.054 1.00 31.74 ? 255 PRO A N 1 ATOM 1976 C CA . PRO A 1 255 ? 5.176 55.132 39.713 1.00 35.23 ? 255 PRO A CA 1 ATOM 1977 C C . PRO A 1 255 ? 4.029 55.563 38.790 1.00 38.66 ? 255 PRO A C 1 ATOM 1978 O O . PRO A 1 255 ? 3.605 56.716 38.829 1.00 43.31 ? 255 PRO A O 1 ATOM 1979 C CB . PRO A 1 255 ? 6.513 55.314 38.993 1.00 32.72 ? 255 PRO A CB 1 ATOM 1980 C CG . PRO A 1 255 ? 7.399 54.317 39.608 1.00 35.54 ? 255 PRO A CG 1 ATOM 1981 C CD . PRO A 1 255 ? 6.541 53.142 40.007 1.00 37.41 ? 255 PRO A CD 1 ATOM 1982 N N . ALA A 1 256 ? 3.540 54.637 37.972 1.00 41.82 ? 256 ALA A N 1 ATOM 1983 C CA . ALA A 1 256 ? 2.461 54.912 37.026 1.00 36.35 ? 256 ALA A CA 1 ATOM 1984 C C . ALA A 1 256 ? 1.088 54.777 37.674 1.00 33.82 ? 256 ALA A C 1 ATOM 1985 O O . ALA A 1 256 ? 0.060 54.883 37.002 1.00 34.32 ? 256 ALA A O 1 ATOM 1986 C CB . ALA A 1 256 ? 2.577 53.986 35.838 1.00 44.05 ? 256 ALA A CB 1 ATOM 1987 N N . TRP A 1 257 ? 1.085 54.538 38.980 1.00 33.22 ? 257 TRP A N 1 ATOM 1988 C CA . TRP A 1 257 ? -0.136 54.426 39.758 1.00 36.74 ? 257 TRP A CA 1 ATOM 1989 C C . TRP A 1 257 ? -0.096 55.433 40.888 1.00 41.19 ? 257 TRP A C 1 ATOM 1990 O O . TRP A 1 257 ? -1.133 55.906 41.353 1.00 42.31 ? 257 TRP A O 1 ATOM 1991 C CB . TRP A 1 257 ? -0.248 53.028 40.331 1.00 34.28 ? 257 TRP A CB 1 ATOM 1992 C CG . TRP A 1 257 ? -1.501 52.757 41.080 1.00 36.12 ? 257 TRP A CG 1 ATOM 1993 C CD1 . TRP A 1 257 ? -2.702 52.387 40.554 1.00 41.63 ? 257 TRP A CD1 1 ATOM 1994 C CD2 . TRP A 1 257 ? -1.679 52.795 42.500 1.00 38.70 ? 257 TRP A CD2 1 ATOM 1995 N NE1 . TRP A 1 257 ? -3.626 52.202 41.556 1.00 46.62 ? 257 TRP A NE1 1 ATOM 1996 C CE2 . TRP A 1 257 ? -3.023 52.442 42.762 1.00 40.96 ? 257 TRP A CE2 1 ATOM 1997 C CE3 . TRP A 1 257 ? -0.835 53.094 43.577 1.00 37.41 ? 257 TRP A CE3 1 ATOM 1998 C CZ2 . TRP A 1 257 ? -3.544 52.382 44.055 1.00 39.04 ? 257 TRP A CZ2 1 ATOM 1999 C CZ3 . TRP A 1 257 ? -1.351 53.027 44.862 1.00 39.77 ? 257 TRP A CZ3 1 ATOM 2000 C CH2 . TRP A 1 257 ? -2.695 52.675 45.090 1.00 42.50 ? 257 TRP A CH2 1 ATOM 2001 N N . ASN A 1 258 ? 1.117 55.748 41.330 1.00 41.10 ? 258 ASN A N 1 ATOM 2002 C CA . ASN A 1 258 ? 1.323 56.729 42.379 1.00 39.05 ? 258 ASN A CA 1 ATOM 2003 C C . ASN A 1 258 ? 0.828 58.101 41.961 1.00 38.55 ? 258 ASN A C 1 ATOM 2004 O O . ASN A 1 258 ? 1.132 58.572 40.862 1.00 37.15 ? 258 ASN A O 1 ATOM 2005 C CB . ASN A 1 258 ? 2.798 56.790 42.762 1.00 38.04 ? 258 ASN A CB 1 ATOM 2006 C CG . ASN A 1 258 ? 3.258 55.561 43.516 1.00 46.55 ? 258 ASN A CG 1 ATOM 2007 O OD1 . ASN A 1 258 ? 2.460 54.685 43.864 1.00 46.21 ? 258 ASN A OD1 1 ATOM 2008 N ND2 . ASN A 1 258 ? 4.556 55.491 43.780 1.00 51.62 ? 258 ASN A ND2 1 ATOM 2009 N N . ALA A 1 259 ? 0.058 58.727 42.848 1.00 38.24 ? 259 ALA A N 1 ATOM 2010 C CA . ALA A 1 259 ? -0.550 60.026 42.578 1.00 39.56 ? 259 ALA A CA 1 ATOM 2011 C C . ALA A 1 259 ? 0.371 61.201 42.915 1.00 36.74 ? 259 ALA A C 1 ATOM 2012 O O . ALA A 1 259 ? 1.149 61.146 43.869 1.00 35.00 ? 259 ALA A O 1 ATOM 2013 C CB . ALA A 1 259 ? -1.867 60.146 43.314 1.00 33.37 ? 259 ALA A CB 1 ATOM 2014 N N . ALA A 1 260 ? 0.280 62.257 42.110 1.00 37.21 ? 260 ALA A N 1 ATOM 2015 C CA . ALA A 1 260 ? 1.057 63.473 42.321 1.00 37.74 ? 260 ALA A CA 1 ATOM 2016 C C . ALA A 1 260 ? 0.148 64.690 42.201 1.00 43.82 ? 260 ALA A C 1 ATOM 2017 O O . ALA A 1 260 ? -0.205 65.114 41.096 1.00 43.32 ? 260 ALA A O 1 ATOM 2018 C CB . ALA A 1 260 ? 2.216 63.556 41.335 1.00 34.72 ? 260 ALA A CB 1 ATOM 2019 N N . TYR A 1 261 ? -0.233 65.241 43.351 1.00 46.47 ? 261 TYR A N 1 ATOM 2020 C CA . TYR A 1 261 ? -1.182 66.347 43.402 1.00 44.31 ? 261 TYR A CA 1 ATOM 2021 C C . TYR A 1 261 ? -0.486 67.690 43.509 1.00 42.90 ? 261 TYR A C 1 ATOM 2022 O O . TYR A 1 261 ? 0.628 67.790 44.037 1.00 41.47 ? 261 TYR A O 1 ATOM 2023 C CB . TYR A 1 261 ? -2.127 66.204 44.592 1.00 38.38 ? 261 TYR A CB 1 ATOM 2024 C CG . TYR A 1 261 ? -2.658 64.816 44.840 1.00 40.90 ? 261 TYR A CG 1 ATOM 2025 C CD1 . TYR A 1 261 ? -1.941 63.908 45.617 1.00 40.80 ? 261 TYR A CD1 1 ATOM 2026 C CD2 . TYR A 1 261 ? -3.892 64.419 44.328 1.00 38.41 ? 261 TYR A CD2 1 ATOM 2027 C CE1 . TYR A 1 261 ? -2.428 62.636 45.861 1.00 45.02 ? 261 TYR A CE1 1 ATOM 2028 C CE2 . TYR A 1 261 ? -4.390 63.146 44.571 1.00 37.26 ? 261 TYR A CE2 1 ATOM 2029 C CZ . TYR A 1 261 ? -3.652 62.261 45.339 1.00 43.25 ? 261 TYR A CZ 1 ATOM 2030 O OH . TYR A 1 261 ? -4.128 60.996 45.588 1.00 48.55 ? 261 TYR A OH 1 ATOM 2031 N N . ARG A 1 262 ? -1.157 68.718 42.997 1.00 44.36 ? 262 ARG A N 1 ATOM 2032 C CA . ARG A 1 262 ? -0.782 70.107 43.249 1.00 48.32 ? 262 ARG A CA 1 ATOM 2033 C C . ARG A 1 262 ? -2.031 70.981 43.237 1.00 49.68 ? 262 ARG A C 1 ATOM 2034 O O . ARG A 1 262 ? -3.005 70.679 42.536 1.00 47.09 ? 262 ARG A O 1 ATOM 2035 C CB . ARG A 1 262 ? 0.260 70.614 42.246 1.00 43.86 ? 262 ARG A CB 1 ATOM 2036 C CG . ARG A 1 262 ? -0.181 70.574 40.806 1.00 51.26 ? 262 ARG A CG 1 ATOM 2037 C CD . ARG A 1 262 ? 0.712 71.430 39.934 1.00 64.68 ? 262 ARG A CD 1 ATOM 2038 N NE . ARG A 1 262 ? 0.063 71.722 38.658 1.00 77.87 ? 262 ARG A NE 1 ATOM 2039 C CZ . ARG A 1 262 ? -0.800 72.716 38.463 1.00 78.47 ? 262 ARG A CZ 1 ATOM 2040 N NH1 . ARG A 1 262 ? -1.122 73.533 39.460 1.00 66.61 ? 262 ARG A NH1 1 ATOM 2041 N NH2 . ARG A 1 262 ? -1.342 72.898 37.266 1.00 85.93 ? 262 ARG A NH2 1 ATOM 2042 N N . ILE A 1 263 ? -1.998 72.050 44.031 1.00 53.11 ? 263 ILE A N 1 ATOM 2043 C CA . ILE A 1 263 ? -3.128 72.967 44.145 1.00 52.43 ? 263 ILE A CA 1 ATOM 2044 C C . ILE A 1 263 ? -3.027 74.006 43.035 1.00 51.77 ? 263 ILE A C 1 ATOM 2045 O O . ILE A 1 263 ? -2.161 74.885 43.065 1.00 50.13 ? 263 ILE A O 1 ATOM 2046 C CB . ILE A 1 263 ? -3.193 73.643 45.538 1.00 52.74 ? 263 ILE A CB 1 ATOM 2047 C CG1 . ILE A 1 263 ? -2.844 72.640 46.645 1.00 50.63 ? 263 ILE A CG1 1 ATOM 2048 C CG2 . ILE A 1 263 ? -4.583 74.221 45.773 1.00 61.94 ? 263 ILE A CG2 1 ATOM 2049 C CD1 . ILE A 1 263 ? -2.290 73.267 47.909 1.00 55.23 ? 263 ILE A CD1 1 ATOM 2050 N N . SER A 1 264 ? -3.915 73.879 42.052 1.00 54.20 ? 264 SER A N 1 ATOM 2051 C CA . SER A 1 264 ? -3.869 74.688 40.834 1.00 55.70 ? 264 SER A CA 1 ATOM 2052 C C . SER A 1 264 ? -4.356 76.114 41.049 1.00 62.92 ? 264 SER A C 1 ATOM 2053 O O . SER A 1 264 ? -4.057 77.003 40.248 1.00 60.94 ? 264 SER A O 1 ATOM 2054 C CB . SER A 1 264 ? -4.687 74.025 39.726 1.00 59.41 ? 264 SER A CB 1 ATOM 2055 O OG . SER A 1 264 ? -6.044 73.889 40.112 1.00 59.94 ? 264 SER A OG 1 ATOM 2056 N N . GLY A 1 265 ? -5.108 76.321 42.128 1.00 64.65 ? 265 GLY A N 1 ATOM 2057 C CA . GLY A 1 265 ? -5.642 77.637 42.471 1.00 64.44 ? 265 GLY A CA 1 ATOM 2058 C C . GLY A 1 265 ? -6.645 77.560 43.604 1.00 58.29 ? 265 GLY A C 1 ATOM 2059 O O . GLY A 1 265 ? -7.025 76.468 44.032 1.00 57.53 ? 265 GLY A O 1 ATOM 2060 N N . GLY A 1 266 ? -7.081 78.723 44.079 1.00 54.99 ? 266 GLY A N 1 ATOM 2061 C CA . GLY A 1 266 ? -7.994 78.803 45.215 1.00 55.93 ? 266 GLY A CA 1 ATOM 2062 C C . GLY A 1 266 ? -7.284 79.200 46.494 1.00 52.12 ? 266 GLY A C 1 ATOM 2063 O O . GLY A 1 266 ? -7.927 79.545 47.486 1.00 55.84 ? 266 GLY A O 1 ATOM 2064 N N . ASP A 1 267 ? -5.954 79.141 46.461 1.00 49.79 ? 267 ASP A N 1 ATOM 2065 C CA . ASP A 1 267 ? -5.105 79.548 47.578 1.00 53.30 ? 267 ASP A CA 1 ATOM 2066 C C . ASP A 1 267 ? -3.875 80.300 47.050 1.00 56.19 ? 267 ASP A C 1 ATOM 2067 O O . ASP A 1 267 ? -2.782 79.729 46.950 1.00 53.32 ? 267 ASP A O 1 ATOM 2068 C CB . ASP A 1 267 ? -4.696 78.329 48.420 1.00 57.20 ? 267 ASP A CB 1 ATOM 2069 C CG . ASP A 1 267 ? -3.730 78.681 49.548 1.00 65.55 ? 267 ASP A CG 1 ATOM 2070 O OD1 . ASP A 1 267 ? -3.813 79.806 50.090 1.00 70.12 ? 267 ASP A OD1 1 ATOM 2071 O OD2 . ASP A 1 267 ? -2.886 77.825 49.894 1.00 64.01 ? 267 ASP A OD2 1 ATOM 2072 N N . PRO A 1 268 ? -4.049 81.594 46.718 1.00 59.25 ? 268 PRO A N 1 ATOM 2073 C CA . PRO A 1 268 ? -2.968 82.374 46.110 1.00 60.69 ? 268 PRO A CA 1 ATOM 2074 C C . PRO A 1 268 ? -1.878 82.770 47.107 1.00 54.67 ? 268 PRO A C 1 ATOM 2075 O O . PRO A 1 268 ? -0.891 83.403 46.729 1.00 55.82 ? 268 PRO A O 1 ATOM 2076 C CB . PRO A 1 268 ? -3.693 83.618 45.591 1.00 57.00 ? 268 PRO A CB 1 ATOM 2077 C CG . PRO A 1 268 ? -4.853 83.780 46.501 1.00 61.43 ? 268 PRO A CG 1 ATOM 2078 C CD . PRO A 1 268 ? -5.273 82.398 46.905 1.00 58.47 ? 268 PRO A CD 1 ATOM 2079 N N . THR A 1 269 ? -2.052 82.375 48.363 1.00 56.02 ? 269 THR A N 1 ATOM 2080 C CA . THR A 1 269 ? -1.203 82.850 49.453 1.00 62.58 ? 269 THR A CA 1 ATOM 2081 C C . THR A 1 269 ? -0.387 81.739 50.143 1.00 69.81 ? 269 THR A C 1 ATOM 2082 O O . THR A 1 269 ? 0.453 82.017 51.007 1.00 65.44 ? 269 THR A O 1 ATOM 2083 C CB . THR A 1 269 ? -2.033 83.690 50.471 1.00 57.81 ? 269 THR A CB 1 ATOM 2084 O OG1 . THR A 1 269 ? -1.352 83.754 51.729 1.00 63.43 ? 269 THR A OG1 1 ATOM 2085 C CG2 . THR A 1 269 ? -3.431 83.097 50.674 1.00 57.49 ? 269 THR A CG2 1 ATOM 2086 N N . GLY A 1 270 ? -0.629 80.490 49.745 1.00 66.68 ? 270 GLY A N 1 ATOM 2087 C CA . GLY A 1 270 ? 0.152 79.350 50.227 1.00 58.37 ? 270 GLY A CA 1 ATOM 2088 C C . GLY A 1 270 ? -0.160 78.921 51.649 1.00 61.33 ? 270 GLY A C 1 ATOM 2089 O O . GLY A 1 270 ? 0.750 78.620 52.428 1.00 65.42 ? 270 GLY A O 1 ATOM 2090 N N . ARG A 1 271 ? -1.448 78.888 51.984 1.00 57.87 ? 271 ARG A N 1 ATOM 2091 C CA . ARG A 1 271 ? -1.903 78.426 53.294 1.00 59.68 ? 271 ARG A CA 1 ATOM 2092 C C . ARG A 1 271 ? -1.880 76.910 53.419 1.00 61.33 ? 271 ARG A C 1 ATOM 2093 O O . ARG A 1 271 ? -1.664 76.374 54.509 1.00 65.63 ? 271 ARG A O 1 ATOM 2094 C CB . ARG A 1 271 ? -3.311 78.949 53.592 1.00 62.10 ? 271 ARG A CB 1 ATOM 2095 C CG . ARG A 1 271 ? -3.365 80.109 54.582 1.00 61.09 ? 271 ARG A CG 1 ATOM 2096 C CD . ARG A 1 271 ? -3.121 81.466 53.933 1.00 57.88 ? 271 ARG A CD 1 ATOM 2097 N NE . ARG A 1 271 ? -1.729 81.659 53.527 1.00 57.15 ? 271 ARG A NE 1 ATOM 2098 C CZ . ARG A 1 271 ? -0.742 82.008 54.349 1.00 61.37 ? 271 ARG A CZ 1 ATOM 2099 N NH1 . ARG A 1 271 ? -0.975 82.202 55.642 1.00 55.13 ? 271 ARG A NH1 1 ATOM 2100 N NH2 . ARG A 1 271 ? 0.486 82.163 53.874 1.00 65.65 ? 271 ARG A NH2 1 ATOM 2101 N N . PHE A 1 272 ? -2.105 76.225 52.300 1.00 58.76 ? 272 PHE A N 1 ATOM 2102 C CA . PHE A 1 272 ? -2.171 74.766 52.287 1.00 58.10 ? 272 PHE A CA 1 ATOM 2103 C C . PHE A 1 272 ? -1.052 74.143 51.471 1.00 55.04 ? 272 PHE A C 1 ATOM 2104 O O . PHE A 1 272 ? -0.548 74.744 50.522 1.00 57.31 ? 272 PHE A O 1 ATOM 2105 C CB . PHE A 1 272 ? -3.508 74.295 51.724 1.00 58.66 ? 272 PHE A CB 1 ATOM 2106 C CG . PHE A 1 272 ? -4.699 74.857 52.434 1.00 56.21 ? 272 PHE A CG 1 ATOM 2107 C CD1 . PHE A 1 272 ? -5.270 76.053 52.015 1.00 51.10 ? 272 PHE A CD1 1 ATOM 2108 C CD2 . PHE A 1 272 ? -5.262 74.183 53.508 1.00 53.12 ? 272 PHE A CD2 1 ATOM 2109 C CE1 . PHE A 1 272 ? -6.378 76.572 52.659 1.00 53.22 ? 272 PHE A CE1 1 ATOM 2110 C CE2 . PHE A 1 272 ? -6.372 74.694 54.157 1.00 60.36 ? 272 PHE A CE2 1 ATOM 2111 C CZ . PHE A 1 272 ? -6.932 75.892 53.731 1.00 62.33 ? 272 PHE A CZ 1 ATOM 2112 N N . ALA A 1 273 ? -0.677 72.928 51.853 1.00 54.19 ? 273 ALA A N 1 ATOM 2113 C CA . ALA A 1 273 ? 0.287 72.136 51.106 1.00 57.38 ? 273 ALA A CA 1 ATOM 2114 C C . ALA A 1 273 ? -0.256 70.723 50.951 1.00 54.69 ? 273 ALA A C 1 ATOM 2115 O O . ALA A 1 273 ? -1.074 70.274 51.761 1.00 55.13 ? 273 ALA A O 1 ATOM 2116 C CB . ALA A 1 273 ? 1.632 72.126 51.813 1.00 62.16 ? 273 ALA A CB 1 ATOM 2117 N N . ILE A 1 274 ? 0.191 70.026 49.911 1.00 50.77 ? 274 ILE A N 1 ATOM 2118 C CA . ILE A 1 274 ? -0.321 68.689 49.636 1.00 49.91 ? 274 ILE A CA 1 ATOM 2119 C C . ILE A 1 274 ? 0.772 67.628 49.483 1.00 47.00 ? 274 ILE A C 1 ATOM 2120 O O . ILE A 1 274 ? 1.780 67.845 48.807 1.00 42.90 ? 274 ILE A O 1 ATOM 2121 C CB . ILE A 1 274 ? -1.298 68.693 48.434 1.00 50.43 ? 274 ILE A CB 1 ATOM 2122 C CG1 . ILE A 1 274 ? -2.104 67.390 48.397 1.00 44.68 ? 274 ILE A CG1 1 ATOM 2123 C CG2 . ILE A 1 274 ? -0.561 68.992 47.118 1.00 50.84 ? 274 ILE A CG2 1 ATOM 2124 C CD1 . ILE A 1 274 ? -3.473 67.541 47.795 1.00 47.43 ? 274 ILE A CD1 1 ATOM 2125 N N . LEU A 1 275 ? 0.553 66.491 50.143 1.00 48.50 ? 275 LEU A N 1 ATOM 2126 C CA . LEU A 1 275 ? 1.460 65.348 50.102 1.00 45.43 ? 275 LEU A CA 1 ATOM 2127 C C . LEU A 1 275 ? 0.668 64.075 49.827 1.00 46.72 ? 275 LEU A C 1 ATOM 2128 O O . LEU A 1 275 ? -0.466 63.928 50.296 1.00 47.20 ? 275 LEU A O 1 ATOM 2129 C CB . LEU A 1 275 ? 2.221 65.211 51.426 1.00 45.89 ? 275 LEU A CB 1 ATOM 2130 C CG . LEU A 1 275 ? 3.200 66.301 51.887 1.00 42.84 ? 275 LEU A CG 1 ATOM 2131 C CD1 . LEU A 1 275 ? 3.556 66.095 53.357 1.00 51.33 ? 275 LEU A CD1 1 ATOM 2132 C CD2 . LEU A 1 275 ? 4.465 66.356 51.031 1.00 38.57 ? 275 LEU A CD2 1 ATOM 2133 N N . THR A 1 276 ? 1.270 63.159 49.070 1.00 46.80 ? 276 THR A N 1 ATOM 2134 C CA . THR A 1 276 ? 0.613 61.906 48.699 1.00 47.66 ? 276 THR A CA 1 ATOM 2135 C C . THR A 1 276 ? 0.874 60.811 49.731 1.00 47.88 ? 276 THR A C 1 ATOM 2136 O O . THR A 1 276 ? 2.026 60.508 50.047 1.00 49.85 ? 276 THR A O 1 ATOM 2137 C CB . THR A 1 276 ? 1.063 61.411 47.306 1.00 44.54 ? 276 THR A CB 1 ATOM 2138 O OG1 . THR A 1 276 ? 1.013 62.492 46.366 1.00 49.22 ? 276 THR A OG1 1 ATOM 2139 C CG2 . THR A 1 276 ? 0.163 60.276 46.829 1.00 41.26 ? 276 THR A CG2 1 ATOM 2140 N N . ASP A 1 277 ? -0.205 60.225 50.246 1.00 47.06 ? 277 ASP A N 1 ATOM 2141 C CA . ASP A 1 277 ? -0.118 59.123 51.201 1.00 53.40 ? 277 ASP A CA 1 ATOM 2142 C C . ASP A 1 277 ? 0.471 57.890 50.514 1.00 62.31 ? 277 ASP A C 1 ATOM 2143 O O . ASP A 1 277 ? -0.151 57.338 49.604 1.00 70.75 ? 277 ASP A O 1 ATOM 2144 C CB . ASP A 1 277 ? -1.502 58.811 51.780 1.00 54.72 ? 277 ASP A CB 1 ATOM 2145 C CG . ASP A 1 277 ? -1.461 57.742 52.856 1.00 59.98 ? 277 ASP A CG 1 ATOM 2146 O OD1 . ASP A 1 277 ? -1.603 58.092 54.045 1.00 62.03 ? 277 ASP A OD1 1 ATOM 2147 O OD2 . ASP A 1 277 ? -1.288 56.553 52.516 1.00 61.07 ? 277 ASP A OD2 1 ATOM 2148 N N . PRO A 1 278 ? 1.669 57.449 50.950 1.00 64.45 ? 278 PRO A N 1 ATOM 2149 C CA . PRO A 1 278 ? 2.390 56.377 50.257 1.00 63.71 ? 278 PRO A CA 1 ATOM 2150 C C . PRO A 1 278 ? 1.558 55.116 50.054 1.00 57.17 ? 278 PRO A C 1 ATOM 2151 O O . PRO A 1 278 ? 1.580 54.541 48.967 1.00 59.30 ? 278 PRO A O 1 ATOM 2152 C CB . PRO A 1 278 ? 3.574 56.093 51.188 1.00 62.75 ? 278 PRO A CB 1 ATOM 2153 C CG . PRO A 1 278 ? 3.798 57.376 51.897 1.00 62.84 ? 278 PRO A CG 1 ATOM 2154 C CD . PRO A 1 278 ? 2.418 57.928 52.127 1.00 64.22 ? 278 PRO A CD 1 ATOM 2155 N N . ASN A 1 279 ? 0.818 54.707 51.080 1.00 52.80 ? 279 ASN A N 1 ATOM 2156 C CA . ASN A 1 279 ? 0.079 53.450 51.031 1.00 61.90 ? 279 ASN A CA 1 ATOM 2157 C C . ASN A 1 279 ? -1.299 53.525 50.385 1.00 59.11 ? 279 ASN A C 1 ATOM 2158 O O . ASN A 1 279 ? -1.609 52.733 49.498 1.00 58.36 ? 279 ASN A O 1 ATOM 2159 C CB . ASN A 1 279 ? -0.012 52.817 52.425 1.00 72.18 ? 279 ASN A CB 1 ATOM 2160 C CG . ASN A 1 279 ? 1.220 51.992 52.771 1.00 83.95 ? 279 ASN A CG 1 ATOM 2161 O OD1 . ASN A 1 279 ? 1.146 50.764 52.875 1.00 92.60 ? 279 ASN A OD1 1 ATOM 2162 N ND2 . ASN A 1 279 ? 2.363 52.661 52.936 1.00 67.15 ? 279 ASN A ND2 1 ATOM 2163 N N . SER A 1 280 ? -2.115 54.478 50.827 1.00 64.54 ? 280 SER A N 1 ATOM 2164 C CA . SER A 1 280 ? -3.514 54.566 50.399 1.00 65.40 ? 280 SER A CA 1 ATOM 2165 C C . SER A 1 280 ? -3.711 55.322 49.081 1.00 53.00 ? 280 SER A C 1 ATOM 2166 O O . SER A 1 280 ? -4.806 55.305 48.510 1.00 47.43 ? 280 SER A O 1 ATOM 2167 C CB . SER A 1 280 ? -4.363 55.205 51.505 1.00 71.23 ? 280 SER A CB 1 ATOM 2168 O OG . SER A 1 280 ? -4.034 56.575 51.680 1.00 60.56 ? 280 SER A OG 1 ATOM 2169 N N . ASN A 1 281 ? -2.644 55.967 48.607 1.00 51.54 ? 281 ASN A N 1 ATOM 2170 C CA . ASN A 1 281 ? -2.678 56.854 47.437 1.00 50.70 ? 281 ASN A CA 1 ATOM 2171 C C . ASN A 1 281 ? -3.769 57.916 47.560 1.00 54.09 ? 281 ASN A C 1 ATOM 2172 O O . ASN A 1 281 ? -4.683 57.997 46.734 1.00 52.73 ? 281 ASN A O 1 ATOM 2173 C CB . ASN A 1 281 ? -2.817 56.062 46.132 1.00 48.37 ? 281 ASN A CB 1 ATOM 2174 C CG . ASN A 1 281 ? -2.160 56.756 44.948 1.00 49.37 ? 281 ASN A CG 1 ATOM 2175 O OD1 . ASN A 1 281 ? -1.109 57.385 45.080 1.00 46.04 ? 281 ASN A OD1 1 ATOM 2176 N ND2 . ASN A 1 281 ? -2.772 56.625 43.778 1.00 42.06 ? 281 ASN A ND2 1 ATOM 2177 N N . ASP A 1 282 ? -3.666 58.710 48.621 1.00 55.16 ? 282 ASP A N 1 ATOM 2178 C CA . ASP A 1 282 ? -4.630 59.761 48.903 1.00 47.82 ? 282 ASP A CA 1 ATOM 2179 C C . ASP A 1 282 ? -3.956 61.121 48.895 1.00 47.73 ? 282 ASP A C 1 ATOM 2180 O O . ASP A 1 282 ? -2.754 61.235 49.149 1.00 47.86 ? 282 ASP A O 1 ATOM 2181 C CB . ASP A 1 282 ? -5.319 59.518 50.250 1.00 50.03 ? 282 ASP A CB 1 ATOM 2182 C CG . ASP A 1 282 ? -6.525 58.598 50.139 1.00 54.68 ? 282 ASP A CG 1 ATOM 2183 O OD1 . ASP A 1 282 ? -7.438 58.892 49.341 1.00 53.83 ? 282 ASP A OD1 1 ATOM 2184 O OD2 . ASP A 1 282 ? -6.573 57.585 50.863 1.00 57.93 ? 282 ASP A OD2 1 ATOM 2185 N N . GLY A 1 283 ? -4.741 62.147 48.585 1.00 47.20 ? 283 GLY A N 1 ATOM 2186 C CA . GLY A 1 283 ? -4.272 63.521 48.638 1.00 47.51 ? 283 GLY A CA 1 ATOM 2187 C C . GLY A 1 283 ? -4.521 64.108 50.008 1.00 56.60 ? 283 GLY A C 1 ATOM 2188 O O . GLY A 1 283 ? -5.642 64.517 50.324 1.00 61.39 ? 283 GLY A O 1 ATOM 2189 N N . LEU A 1 284 ? -3.477 64.136 50.830 1.00 55.32 ? 284 LEU A N 1 ATOM 2190 C CA . LEU A 1 284 ? -3.578 64.707 52.166 1.00 55.17 ? 284 LEU A CA 1 ATOM 2191 C C . LEU A 1 284 ? -3.294 66.201 52.106 1.00 55.59 ? 284 LEU A C 1 ATOM 2192 O O . LEU A 1 284 ? -2.152 66.622 51.907 1.00 54.63 ? 284 LEU A O 1 ATOM 2193 C CB . LEU A 1 284 ? -2.627 64.002 53.142 1.00 51.18 ? 284 LEU A CB 1 ATOM 2194 C CG . LEU A 1 284 ? -2.743 62.479 53.308 1.00 57.04 ? 284 LEU A CG 1 ATOM 2195 C CD1 . LEU A 1 284 ? -1.569 61.933 54.119 1.00 59.95 ? 284 LEU A CD1 1 ATOM 2196 C CD2 . LEU A 1 284 ? -4.080 62.053 53.927 1.00 56.19 ? 284 LEU A CD2 1 ATOM 2197 N N . VAL A 1 285 ? -4.349 66.997 52.251 1.00 53.93 ? 285 VAL A N 1 ATOM 2198 C CA . VAL A 1 285 ? -4.206 68.446 52.276 1.00 56.34 ? 285 VAL A CA 1 ATOM 2199 C C . VAL A 1 285 ? -4.057 68.892 53.719 1.00 60.14 ? 285 VAL A C 1 ATOM 2200 O O . VAL A 1 285 ? -4.894 68.580 54.570 1.00 60.76 ? 285 VAL A O 1 ATOM 2201 C CB . VAL A 1 285 ? -5.402 69.182 51.636 1.00 58.79 ? 285 VAL A CB 1 ATOM 2202 C CG1 . VAL A 1 285 ? -5.003 70.609 51.275 1.00 54.47 ? 285 VAL A CG1 1 ATOM 2203 C CG2 . VAL A 1 285 ? -5.902 68.448 50.403 1.00 59.56 ? 285 VAL A CG2 1 ATOM 2204 N N . THR A 1 286 ? -2.982 69.625 53.983 1.00 59.33 ? 286 THR A N 1 ATOM 2205 C CA . THR A 1 286 ? -2.644 70.040 55.336 1.00 62.71 ? 286 THR A CA 1 ATOM 2206 C C . THR A 1 286 ? -2.394 71.546 55.418 1.00 61.41 ? 286 THR A C 1 ATOM 2207 O O . THR A 1 286 ? -1.812 72.135 54.503 1.00 63.44 ? 286 THR A O 1 ATOM 2208 C CB . THR A 1 286 ? -1.426 69.240 55.885 1.00 62.72 ? 286 THR A CB 1 ATOM 2209 O OG1 . THR A 1 286 ? -0.900 69.892 57.047 1.00 71.72 ? 286 THR A OG1 1 ATOM 2210 C CG2 . THR A 1 286 ? -0.314 69.107 54.834 1.00 57.52 ? 286 THR A CG2 1 ATOM 2211 N N . VAL A 1 287 ? -2.849 72.159 56.511 1.00 58.07 ? 287 VAL A N 1 ATOM 2212 C CA . VAL A 1 287 ? -2.617 73.581 56.762 1.00 58.87 ? 287 VAL A CA 1 ATOM 2213 C C . VAL A 1 287 ? -1.145 73.797 57.092 1.00 60.36 ? 287 VAL A C 1 ATOM 2214 O O . VAL A 1 287 ? -0.683 73.411 58.162 1.00 59.57 ? 287 VAL A O 1 ATOM 2215 C CB . VAL A 1 287 ? -3.468 74.116 57.932 1.00 56.77 ? 287 VAL A CB 1 ATOM 2216 C CG1 . VAL A 1 287 ? -3.472 75.634 57.924 1.00 62.95 ? 287 VAL A CG1 1 ATOM 2217 C CG2 . VAL A 1 287 ? -4.880 73.600 57.848 1.00 54.36 ? 287 VAL A CG2 1 ATOM 2218 N N . VAL A 1 288 ? -0.415 74.406 56.164 1.00 60.23 ? 288 VAL A N 1 ATOM 2219 C CA . VAL A 1 288 ? 1.024 74.594 56.324 1.00 61.61 ? 288 VAL A CA 1 ATOM 2220 C C . VAL A 1 288 ? 1.354 75.989 56.879 1.00 65.22 ? 288 VAL A C 1 ATOM 2221 O O . VAL A 1 288 ? 2.407 76.189 57.492 1.00 61.04 ? 288 VAL A O 1 ATOM 2222 C CB . VAL A 1 288 ? 1.789 74.279 54.999 1.00 58.46 ? 288 VAL A CB 1 ATOM 2223 C CG1 . VAL A 1 288 ? 1.821 75.494 54.055 1.00 64.09 ? 288 VAL A CG1 1 ATOM 2224 C CG2 . VAL A 1 288 ? 3.199 73.761 55.288 1.00 51.44 ? 288 VAL A CG2 1 ATOM 2225 N N . LYS A 1 289 ? 0.444 76.938 56.657 1.00 62.09 ? 289 LYS A N 1 ATOM 2226 C CA . LYS A 1 289 ? 0.550 78.295 57.198 1.00 61.30 ? 289 LYS A CA 1 ATOM 2227 C C . LYS A 1 289 ? -0.798 78.729 57.783 1.00 68.56 ? 289 LYS A C 1 ATOM 2228 O O . LYS A 1 289 ? -1.841 78.479 57.171 1.00 69.12 ? 289 LYS A O 1 ATOM 2229 C CB . LYS A 1 289 ? 1.024 79.279 56.124 1.00 56.37 ? 289 LYS A CB 1 ATOM 2230 C CG . LYS A 1 289 ? 2.524 79.244 55.871 1.00 59.32 ? 289 LYS A CG 1 ATOM 2231 C CD . LYS A 1 289 ? 2.987 80.480 55.125 1.00 63.86 ? 289 LYS A CD 1 ATOM 2232 C CE . LYS A 1 289 ? 4.414 80.335 54.630 1.00 61.17 ? 289 LYS A CE 1 ATOM 2233 N NZ . LYS A 1 289 ? 4.757 81.404 53.650 1.00 60.54 ? 289 LYS A NZ 1 ATOM 2234 N N . PRO A 1 290 ? -0.782 79.391 58.962 1.00 68.17 ? 290 PRO A N 1 ATOM 2235 C CA . PRO A 1 290 ? -2.006 79.639 59.738 1.00 60.94 ? 290 PRO A CA 1 ATOM 2236 C C . PRO A 1 290 ? -2.962 80.605 59.051 1.00 59.45 ? 290 PRO A C 1 ATOM 2237 O O . PRO A 1 290 ? -2.523 81.496 58.326 1.00 59.60 ? 290 PRO A O 1 ATOM 2238 C CB . PRO A 1 290 ? -1.479 80.248 61.038 1.00 67.19 ? 290 PRO A CB 1 ATOM 2239 C CG . PRO A 1 290 ? -0.174 80.866 60.663 1.00 70.04 ? 290 PRO A CG 1 ATOM 2240 C CD . PRO A 1 290 ? 0.408 79.968 59.618 1.00 61.74 ? 290 PRO A CD 1 ATOM 2241 N N . ILE A 1 291 ? -4.259 80.421 59.278 1.00 59.90 ? 291 ILE A N 1 ATOM 2242 C CA . ILE A 1 291 ? -5.268 81.238 58.608 1.00 62.04 ? 291 ILE A CA 1 ATOM 2243 C C . ILE A 1 291 ? -6.012 82.155 59.585 1.00 64.63 ? 291 ILE A C 1 ATOM 2244 O O . ILE A 1 291 ? -6.098 81.864 60.781 1.00 65.36 ? 291 ILE A O 1 ATOM 2245 C CB . ILE A 1 291 ? -6.268 80.374 57.780 1.00 57.87 ? 291 ILE A CB 1 ATOM 2246 C CG1 . ILE A 1 291 ? -7.512 80.008 58.592 1.00 60.56 ? 291 ILE A CG1 1 ATOM 2247 C CG2 . ILE A 1 291 ? -5.590 79.119 57.229 1.00 54.32 ? 291 ILE A CG2 1 ATOM 2248 C CD1 . ILE A 1 291 ? -8.764 79.915 57.750 1.00 55.06 ? 291 ILE A CD1 1 ATOM 2249 N N . ASP A 1 292 ? -6.536 83.264 59.063 1.00 61.58 ? 292 ASP A N 1 ATOM 2250 C CA . ASP A 1 292 ? -7.328 84.210 59.853 1.00 69.48 ? 292 ASP A CA 1 ATOM 2251 C C . ASP A 1 292 ? -8.776 84.232 59.359 1.00 64.56 ? 292 ASP A C 1 ATOM 2252 O O . ASP A 1 292 ? -9.038 84.594 58.212 1.00 70.67 ? 292 ASP A O 1 ATOM 2253 C CB . ASP A 1 292 ? -6.700 85.611 59.789 1.00 81.84 ? 292 ASP A CB 1 ATOM 2254 C CG . ASP A 1 292 ? -7.434 86.629 60.650 1.00 79.04 ? 292 ASP A CG 1 ATOM 2255 O OD1 . ASP A 1 292 ? -6.918 86.973 61.738 1.00 77.88 ? 292 ASP A OD1 1 ATOM 2256 O OD2 . ASP A 1 292 ? -8.527 87.082 60.247 1.00 73.98 ? 292 ASP A OD2 1 ATOM 2257 N N . PHE A 1 293 ? -9.708 83.848 60.229 1.00 59.28 ? 293 PHE A N 1 ATOM 2258 C CA . PHE A 1 293 ? -11.122 83.727 59.858 1.00 62.17 ? 293 PHE A CA 1 ATOM 2259 C C . PHE A 1 293 ? -11.717 85.052 59.389 1.00 71.29 ? 293 PHE A C 1 ATOM 2260 O O . PHE A 1 293 ? -12.564 85.085 58.491 1.00 73.17 ? 293 PHE A O 1 ATOM 2261 C CB . PHE A 1 293 ? -11.943 83.166 61.025 1.00 61.45 ? 293 PHE A CB 1 ATOM 2262 C CG . PHE A 1 293 ? -13.416 83.046 60.737 1.00 64.74 ? 293 PHE A CG 1 ATOM 2263 C CD1 . PHE A 1 293 ? -13.937 81.881 60.191 1.00 76.04 ? 293 PHE A CD1 1 ATOM 2264 C CD2 . PHE A 1 293 ? -14.284 84.095 61.019 1.00 76.13 ? 293 PHE A CD2 1 ATOM 2265 C CE1 . PHE A 1 293 ? -15.303 81.763 59.922 1.00 79.13 ? 293 PHE A CE1 1 ATOM 2266 C CE2 . PHE A 1 293 ? -15.649 83.988 60.752 1.00 81.76 ? 293 PHE A CE2 1 ATOM 2267 C CZ . PHE A 1 293 ? -16.159 82.818 60.205 1.00 75.86 ? 293 PHE A CZ 1 ATOM 2268 N N . GLU A 1 294 ? -11.260 86.139 60.000 1.00 72.97 ? 294 GLU A N 1 ATOM 2269 C CA . GLU A 1 294 ? -11.816 87.463 59.745 1.00 70.87 ? 294 GLU A CA 1 ATOM 2270 C C . GLU A 1 294 ? -11.321 88.061 58.428 1.00 73.78 ? 294 GLU A C 1 ATOM 2271 O O . GLU A 1 294 ? -11.776 89.129 58.014 1.00 82.17 ? 294 GLU A O 1 ATOM 2272 C CB . GLU A 1 294 ? -11.524 88.399 60.921 1.00 75.59 ? 294 GLU A CB 1 ATOM 2273 C CG . GLU A 1 294 ? -12.134 87.943 62.250 1.00 76.41 ? 294 GLU A CG 1 ATOM 2274 C CD . GLU A 1 294 ? -11.379 86.794 62.902 1.00 64.30 ? 294 GLU A CD 1 ATOM 2275 O OE1 . GLU A 1 294 ? -10.136 86.744 62.799 1.00 68.01 ? 294 GLU A OE1 1 ATOM 2276 O OE2 . GLU A 1 294 ? -12.035 85.939 63.529 1.00 53.26 ? 294 GLU A OE2 1 ATOM 2277 N N . THR A 1 295 ? -10.387 87.370 57.777 1.00 72.50 ? 295 THR A N 1 ATOM 2278 C CA . THR A 1 295 ? -9.956 87.731 56.426 1.00 75.71 ? 295 THR A CA 1 ATOM 2279 C C . THR A 1 295 ? -10.480 86.731 55.387 1.00 75.42 ? 295 THR A C 1 ATOM 2280 O O . THR A 1 295 ? -10.713 87.097 54.232 1.00 76.74 ? 295 THR A O 1 ATOM 2281 C CB . THR A 1 295 ? -8.411 87.891 56.310 1.00 74.93 ? 295 THR A CB 1 ATOM 2282 O OG1 . THR A 1 295 ? -7.756 86.734 56.841 1.00 74.89 ? 295 THR A OG1 1 ATOM 2283 C CG2 . THR A 1 295 ? -7.929 89.131 57.067 1.00 77.55 ? 295 THR A CG2 1 ATOM 2284 N N . ASN A 1 296 ? -10.672 85.480 55.817 1.00 74.30 ? 296 ASN A N 1 ATOM 2285 C CA . ASN A 1 296 ? -11.187 84.397 54.967 1.00 67.80 ? 296 ASN A CA 1 ATOM 2286 C C . ASN A 1 296 ? -12.095 83.433 55.731 1.00 68.90 ? 296 ASN A C 1 ATOM 2287 O O . ASN A 1 296 ? -11.638 82.723 56.631 1.00 70.73 ? 296 ASN A O 1 ATOM 2288 C CB . ASN A 1 296 ? -10.033 83.607 54.344 1.00 58.07 ? 296 ASN A CB 1 ATOM 2289 C CG . ASN A 1 296 ? -9.372 84.340 53.201 1.00 58.43 ? 296 ASN A CG 1 ATOM 2290 O OD1 . ASN A 1 296 ? -10.027 84.733 52.236 1.00 64.93 ? 296 ASN A OD1 1 ATOM 2291 N ND2 . ASN A 1 296 ? -8.062 84.517 53.295 1.00 55.21 ? 296 ASN A ND2 1 ATOM 2292 N N . ARG A 1 297 ? -13.374 83.399 55.364 1.00 70.91 ? 297 ARG A N 1 ATOM 2293 C CA . ARG A 1 297 ? -14.345 82.533 56.043 1.00 74.98 ? 297 ARG A CA 1 ATOM 2294 C C . ARG A 1 297 ? -14.521 81.179 55.352 1.00 75.72 ? 297 ARG A C 1 ATOM 2295 O O . ARG A 1 297 ? -14.946 80.204 55.977 1.00 72.30 ? 297 ARG A O 1 ATOM 2296 C CB . ARG A 1 297 ? -15.704 83.232 56.181 1.00 81.98 ? 297 ARG A CB 1 ATOM 2297 C CG . ARG A 1 297 ? -15.664 84.557 56.939 1.00 84.26 ? 297 ARG A CG 1 ATOM 2298 C CD . ARG A 1 297 ? -17.048 84.984 57.438 1.00 89.91 ? 297 ARG A CD 1 ATOM 2299 N NE . ARG A 1 297 ? -18.088 84.924 56.406 1.00 95.29 ? 297 ARG A NE 1 ATOM 2300 C CZ . ARG A 1 297 ? -18.259 85.825 55.438 1.00 100.92 ? 297 ARG A CZ 1 ATOM 2301 N NH1 . ARG A 1 297 ? -17.452 86.876 55.334 1.00 102.33 ? 297 ARG A NH1 1 ATOM 2302 N NH2 . ARG A 1 297 ? -19.240 85.669 54.557 1.00 103.50 ? 297 ARG A NH2 1 ATOM 2303 N N . MET A 1 298 ? -14.201 81.132 54.061 1.00 79.70 ? 298 MET A N 1 ATOM 2304 C CA . MET A 1 298 ? -14.363 79.926 53.253 1.00 77.74 ? 298 MET A CA 1 ATOM 2305 C C . MET A 1 298 ? -13.253 79.856 52.208 1.00 72.14 ? 298 MET A C 1 ATOM 2306 O O . MET A 1 298 ? -12.838 80.881 51.661 1.00 72.65 ? 298 MET A O 1 ATOM 2307 C CB . MET A 1 298 ? -15.746 79.921 52.579 1.00 81.21 ? 298 MET A CB 1 ATOM 2308 C CG . MET A 1 298 ? -16.069 78.690 51.709 1.00 91.81 ? 298 MET A CG 1 ATOM 2309 S SD . MET A 1 298 ? -16.371 77.129 52.592 1.00 98.77 ? 298 MET A SD 1 ATOM 2310 C CE . MET A 1 298 ? -17.921 77.475 53.437 1.00 89.57 ? 298 MET A CE 1 ATOM 2311 N N . PHE A 1 299 ? -12.767 78.645 51.950 1.00 70.36 ? 299 PHE A N 1 ATOM 2312 C CA . PHE A 1 299 ? -11.819 78.410 50.868 1.00 69.21 ? 299 PHE A CA 1 ATOM 2313 C C . PHE A 1 299 ? -12.408 77.485 49.820 1.00 70.01 ? 299 PHE A C 1 ATOM 2314 O O . PHE A 1 299 ? -12.997 76.450 50.150 1.00 68.83 ? 299 PHE A O 1 ATOM 2315 C CB . PHE A 1 299 ? -10.517 77.815 51.395 1.00 70.05 ? 299 PHE A CB 1 ATOM 2316 C CG . PHE A 1 299 ? -9.574 78.828 51.962 1.00 68.39 ? 299 PHE A CG 1 ATOM 2317 C CD1 . PHE A 1 299 ? -9.481 79.014 53.337 1.00 62.76 ? 299 PHE A CD1 1 ATOM 2318 C CD2 . PHE A 1 299 ? -8.769 79.593 51.120 1.00 66.64 ? 299 PHE A CD2 1 ATOM 2319 C CE1 . PHE A 1 299 ? -8.600 79.948 53.868 1.00 61.42 ? 299 PHE A CE1 1 ATOM 2320 C CE2 . PHE A 1 299 ? -7.884 80.532 51.639 1.00 57.73 ? 299 PHE A CE2 1 ATOM 2321 C CZ . PHE A 1 299 ? -7.799 80.710 53.016 1.00 62.55 ? 299 PHE A CZ 1 ATOM 2322 N N . VAL A 1 300 ? -12.253 77.875 48.558 1.00 64.84 ? 300 VAL A N 1 ATOM 2323 C CA . VAL A 1 300 ? -12.644 77.039 47.428 1.00 66.22 ? 300 VAL A CA 1 ATOM 2324 C C . VAL A 1 300 ? -11.414 76.857 46.554 1.00 60.81 ? 300 VAL A C 1 ATOM 2325 O O . VAL A 1 300 ? -10.993 77.783 45.856 1.00 52.97 ? 300 VAL A O 1 ATOM 2326 C CB . VAL A 1 300 ? -13.819 77.654 46.618 1.00 66.63 ? 300 VAL A CB 1 ATOM 2327 C CG1 . VAL A 1 300 ? -14.088 76.852 45.348 1.00 64.83 ? 300 VAL A CG1 1 ATOM 2328 C CG2 . VAL A 1 300 ? -15.084 77.729 47.472 1.00 77.37 ? 300 VAL A CG2 1 ATOM 2329 N N . LEU A 1 301 ? -10.830 75.663 46.616 1.00 61.07 ? 301 LEU A N 1 ATOM 2330 C CA . LEU A 1 301 ? -9.601 75.377 45.878 1.00 62.58 ? 301 LEU A CA 1 ATOM 2331 C C . LEU A 1 301 ? -9.677 74.173 44.939 1.00 57.87 ? 301 LEU A C 1 ATOM 2332 O O . LEU A 1 301 ? -10.189 73.110 45.300 1.00 54.13 ? 301 LEU A O 1 ATOM 2333 C CB . LEU A 1 301 ? -8.382 75.280 46.815 1.00 58.20 ? 301 LEU A CB 1 ATOM 2334 C CG . LEU A 1 301 ? -8.457 74.804 48.270 1.00 52.19 ? 301 LEU A CG 1 ATOM 2335 C CD1 . LEU A 1 301 ? -8.926 73.369 48.380 1.00 52.85 ? 301 LEU A CD1 1 ATOM 2336 C CD2 . LEU A 1 301 ? -7.093 74.959 48.923 1.00 47.43 ? 301 LEU A CD2 1 ATOM 2337 N N . THR A 1 302 ? -9.162 74.375 43.727 1.00 55.48 ? 302 THR A N 1 ATOM 2338 C CA . THR A 1 302 ? -9.064 73.329 42.714 1.00 57.93 ? 302 THR A CA 1 ATOM 2339 C C . THR A 1 302 ? -7.719 72.615 42.815 1.00 59.45 ? 302 THR A C 1 ATOM 2340 O O . THR A 1 302 ? -6.674 73.250 43.011 1.00 54.33 ? 302 THR A O 1 ATOM 2341 C CB . THR A 1 302 ? -9.235 73.892 41.282 1.00 59.91 ? 302 THR A CB 1 ATOM 2342 O OG1 . THR A 1 302 ? -8.398 75.045 41.111 1.00 56.08 ? 302 THR A OG1 1 ATOM 2343 C CG2 . THR A 1 302 ? -10.689 74.274 41.017 1.00 57.85 ? 302 THR A CG2 1 ATOM 2344 N N . VAL A 1 303 ? -7.758 71.293 42.675 1.00 59.45 ? 303 VAL A N 1 ATOM 2345 C CA . VAL A 1 303 ? -6.571 70.456 42.827 1.00 51.51 ? 303 VAL A CA 1 ATOM 2346 C C . VAL A 1 303 ? -6.460 69.432 41.686 1.00 52.59 ? 303 VAL A C 1 ATOM 2347 O O . VAL A 1 303 ? -7.409 68.700 41.388 1.00 46.60 ? 303 VAL A O 1 ATOM 2348 C CB . VAL A 1 303 ? -6.528 69.792 44.233 1.00 41.63 ? 303 VAL A CB 1 ATOM 2349 C CG1 . VAL A 1 303 ? -7.775 68.953 44.487 1.00 44.66 ? 303 VAL A CG1 1 ATOM 2350 C CG2 . VAL A 1 303 ? -5.262 68.976 44.417 1.00 53.70 ? 303 VAL A CG2 1 ATOM 2351 N N . ALA A 1 304 ? -5.290 69.407 41.050 1.00 52.67 ? 304 ALA A N 1 ATOM 2352 C CA . ALA A 1 304 ? -5.047 68.581 39.873 1.00 47.76 ? 304 ALA A CA 1 ATOM 2353 C C . ALA A 1 304 ? -4.273 67.316 40.214 1.00 51.23 ? 304 ALA A C 1 ATOM 2354 O O . ALA A 1 304 ? -3.291 67.362 40.960 1.00 52.42 ? 304 ALA A O 1 ATOM 2355 C CB . ALA A 1 304 ? -4.300 69.384 38.816 1.00 49.15 ? 304 ALA A CB 1 ATOM 2356 N N . ALA A 1 305 ? -4.720 66.194 39.652 1.00 50.86 ? 305 ALA A N 1 ATOM 2357 C CA . ALA A 1 305 ? -4.059 64.899 39.831 1.00 48.41 ? 305 ALA A CA 1 ATOM 2358 C C . ALA A 1 305 ? -3.158 64.536 38.647 1.00 49.05 ? 305 ALA A C 1 ATOM 2359 O O . ALA A 1 305 ? -3.310 65.071 37.546 1.00 49.72 ? 305 ALA A O 1 ATOM 2360 C CB . ALA A 1 305 ? -5.089 63.805 40.073 1.00 43.19 ? 305 ALA A CB 1 ATOM 2361 N N . GLU A 1 306 ? -2.228 63.615 38.891 1.00 49.15 ? 306 GLU A N 1 ATOM 2362 C CA . GLU A 1 306 ? -1.225 63.200 37.913 1.00 45.03 ? 306 GLU A CA 1 ATOM 2363 C C . GLU A 1 306 ? -0.483 61.988 38.471 1.00 42.49 ? 306 GLU A C 1 ATOM 2364 O O . GLU A 1 306 ? -0.734 61.578 39.603 1.00 41.92 ? 306 GLU A O 1 ATOM 2365 C CB . GLU A 1 306 ? -0.245 64.348 37.658 1.00 43.39 ? 306 GLU A CB 1 ATOM 2366 C CG . GLU A 1 306 ? 0.587 64.220 36.398 1.00 52.74 ? 306 GLU A CG 1 ATOM 2367 C CD . GLU A 1 306 ? 1.366 65.484 36.095 1.00 64.92 ? 306 GLU A CD 1 ATOM 2368 O OE1 . GLU A 1 306 ? 0.733 66.503 35.741 1.00 61.03 ? 306 GLU A OE1 1 ATOM 2369 O OE2 . GLU A 1 306 ? 2.611 65.457 36.207 1.00 69.78 ? 306 GLU A OE2 1 ATOM 2370 N N . ASN A 1 307 ? 0.416 61.409 37.678 1.00 41.60 ? 307 ASN A N 1 ATOM 2371 C CA . ASN A 1 307 ? 1.298 60.347 38.156 1.00 35.78 ? 307 ASN A CA 1 ATOM 2372 C C . ASN A 1 307 ? 2.752 60.799 38.181 1.00 37.54 ? 307 ASN A C 1 ATOM 2373 O O . ASN A 1 307 ? 3.091 61.841 37.618 1.00 41.49 ? 307 ASN A O 1 ATOM 2374 C CB . ASN A 1 307 ? 1.144 59.086 37.306 1.00 37.03 ? 307 ASN A CB 1 ATOM 2375 C CG . ASN A 1 307 ? -0.194 58.403 37.509 1.00 37.03 ? 307 ASN A CG 1 ATOM 2376 O OD1 . ASN A 1 307 ? -0.867 58.050 36.544 1.00 38.27 ? 307 ASN A OD1 1 ATOM 2377 N ND2 . ASN A 1 307 ? -0.583 58.205 38.763 1.00 31.65 ? 307 ASN A ND2 1 ATOM 2378 N N . GLN A 1 308 ? 3.603 60.012 38.834 1.00 31.46 ? 308 GLN A N 1 ATOM 2379 C CA . GLN A 1 308 ? 5.022 60.348 38.981 1.00 35.26 ? 308 GLN A CA 1 ATOM 2380 C C . GLN A 1 308 ? 5.765 60.309 37.650 1.00 44.55 ? 308 GLN A C 1 ATOM 2381 O O . GLN A 1 308 ? 6.749 61.027 37.452 1.00 48.41 ? 308 GLN A O 1 ATOM 2382 C CB . GLN A 1 308 ? 5.693 59.413 39.985 1.00 35.60 ? 308 GLN A CB 1 ATOM 2383 C CG . GLN A 1 308 ? 5.063 59.445 41.373 1.00 39.26 ? 308 GLN A CG 1 ATOM 2384 C CD . GLN A 1 308 ? 5.676 58.446 42.339 1.00 39.63 ? 308 GLN A CD 1 ATOM 2385 O OE1 . GLN A 1 308 ? 5.388 58.479 43.531 1.00 48.86 ? 308 GLN A OE1 1 ATOM 2386 N NE2 . GLN A 1 308 ? 6.516 57.553 41.831 1.00 38.42 ? 308 GLN A NE2 1 ATOM 2387 N N . VAL A 1 309 ? 5.279 59.466 36.746 1.00 44.55 ? 309 VAL A N 1 ATOM 2388 C CA . VAL A 1 309 ? 5.836 59.315 35.411 1.00 40.22 ? 309 VAL A CA 1 ATOM 2389 C C . VAL A 1 309 ? 4.770 59.771 34.399 1.00 39.31 ? 309 VAL A C 1 ATOM 2390 O O . VAL A 1 309 ? 3.586 59.510 34.605 1.00 39.52 ? 309 VAL A O 1 ATOM 2391 C CB . VAL A 1 309 ? 6.312 57.841 35.186 1.00 46.55 ? 309 VAL A CB 1 ATOM 2392 C CG1 . VAL A 1 309 ? 5.221 56.837 35.562 1.00 35.52 ? 309 VAL A CG1 1 ATOM 2393 C CG2 . VAL A 1 309 ? 6.823 57.604 33.757 1.00 58.90 ? 309 VAL A CG2 1 ATOM 2394 N N . PRO A 1 310 ? 5.180 60.494 33.332 1.00 47.01 ? 310 PRO A N 1 ATOM 2395 C CA . PRO A 1 310 ? 4.266 61.020 32.305 1.00 41.17 ? 310 PRO A CA 1 ATOM 2396 C C . PRO A 1 310 ? 3.225 60.028 31.787 1.00 40.04 ? 310 PRO A C 1 ATOM 2397 O O . PRO A 1 310 ? 3.469 58.819 31.772 1.00 39.02 ? 310 PRO A O 1 ATOM 2398 C CB . PRO A 1 310 ? 5.213 61.405 31.169 1.00 37.77 ? 310 PRO A CB 1 ATOM 2399 C CG . PRO A 1 310 ? 6.461 61.791 31.852 1.00 43.13 ? 310 PRO A CG 1 ATOM 2400 C CD . PRO A 1 310 ? 6.576 60.893 33.056 1.00 51.93 ? 310 PRO A CD 1 ATOM 2401 N N . LEU A 1 311 ? 2.076 60.558 31.367 1.00 40.44 ? 311 LEU A N 1 ATOM 2402 C CA . LEU A 1 311 ? 0.993 59.765 30.789 1.00 35.90 ? 311 LEU A CA 1 ATOM 2403 C C . LEU A 1 311 ? 1.341 59.354 29.361 1.00 40.81 ? 311 LEU A C 1 ATOM 2404 O O . LEU A 1 311 ? 2.152 60.009 28.704 1.00 42.50 ? 311 LEU A O 1 ATOM 2405 C CB . LEU A 1 311 ? -0.309 60.568 30.804 1.00 33.29 ? 311 LEU A CB 1 ATOM 2406 C CG . LEU A 1 311 ? -1.636 59.846 30.554 1.00 36.22 ? 311 LEU A CG 1 ATOM 2407 C CD1 . LEU A 1 311 ? -2.126 59.120 31.799 1.00 38.73 ? 311 LEU A CD1 1 ATOM 2408 C CD2 . LEU A 1 311 ? -2.680 60.837 30.084 1.00 44.76 ? 311 LEU A CD2 1 ATOM 2409 N N . ALA A 1 312 ? 0.729 58.268 28.889 1.00 40.14 ? 312 ALA A N 1 ATOM 2410 C CA . ALA A 1 312 ? 0.997 57.736 27.551 1.00 39.48 ? 312 ALA A CA 1 ATOM 2411 C C . ALA A 1 312 ? 0.481 58.650 26.440 1.00 46.69 ? 312 ALA A C 1 ATOM 2412 O O . ALA A 1 312 ? -0.449 59.435 26.646 1.00 46.51 ? 312 ALA A O 1 ATOM 2413 C CB . ALA A 1 312 ? 0.417 56.339 27.404 1.00 30.96 ? 312 ALA A CB 1 ATOM 2414 N N . LYS A 1 313 ? 1.095 58.516 25.267 1.00 45.78 ? 313 LYS A N 1 ATOM 2415 C CA . LYS A 1 313 ? 0.870 59.384 24.106 1.00 39.89 ? 313 LYS A CA 1 ATOM 2416 C C . LYS A 1 313 ? -0.583 59.797 23.816 1.00 44.58 ? 313 LYS A C 1 ATOM 2417 O O . LYS A 1 313 ? -0.942 60.961 23.995 1.00 55.22 ? 313 LYS A O 1 ATOM 2418 C CB . LYS A 1 313 ? 1.524 58.773 22.856 1.00 54.60 ? 313 LYS A CB 1 ATOM 2419 C CG . LYS A 1 313 ? 1.493 57.230 22.801 1.00 59.92 ? 313 LYS A CG 1 ATOM 2420 C CD . LYS A 1 313 ? 2.000 56.678 21.465 1.00 63.03 ? 313 LYS A CD 1 ATOM 2421 C CE . LYS A 1 313 ? 0.918 56.723 20.383 1.00 55.32 ? 313 LYS A CE 1 ATOM 2422 N NZ . LYS A 1 313 ? 1.442 56.319 19.048 1.00 57.93 ? 313 LYS A NZ 1 ATOM 2423 N N . GLY A 1 314 ? -1.412 58.851 23.386 1.00 37.59 ? 314 GLY A N 1 ATOM 2424 C CA . GLY A 1 314 ? -2.739 59.178 22.864 1.00 35.60 ? 314 GLY A CA 1 ATOM 2425 C C . GLY A 1 314 ? -3.883 59.296 23.855 1.00 37.57 ? 314 GLY A C 1 ATOM 2426 O O . GLY A 1 314 ? -5.025 59.516 23.454 1.00 32.63 ? 314 GLY A O 1 ATOM 2427 N N . ILE A 1 315 ? -3.588 59.155 25.144 1.00 42.50 ? 315 ILE A N 1 ATOM 2428 C CA . ILE A 1 315 ? -4.629 59.152 26.173 1.00 36.30 ? 315 ILE A CA 1 ATOM 2429 C C . ILE A 1 315 ? -5.046 60.571 26.549 1.00 44.19 ? 315 ILE A C 1 ATOM 2430 O O . ILE A 1 315 ? -4.207 61.470 26.647 1.00 41.74 ? 315 ILE A O 1 ATOM 2431 C CB . ILE A 1 315 ? -4.195 58.378 27.449 1.00 38.06 ? 315 ILE A CB 1 ATOM 2432 C CG1 . ILE A 1 315 ? -3.519 57.044 27.097 1.00 37.07 ? 315 ILE A CG1 1 ATOM 2433 C CG2 . ILE A 1 315 ? -5.385 58.175 28.402 1.00 44.98 ? 315 ILE A CG2 1 ATOM 2434 C CD1 . ILE A 1 315 ? -4.456 55.948 26.597 1.00 42.11 ? 315 ILE A CD1 1 ATOM 2435 N N . GLN A 1 316 ? -6.350 60.748 26.757 1.00 47.82 ? 316 GLN A N 1 ATOM 2436 C CA . GLN A 1 316 ? -6.942 62.037 27.107 1.00 48.65 ? 316 GLN A CA 1 ATOM 2437 C C . GLN A 1 316 ? -6.796 62.337 28.591 1.00 52.11 ? 316 GLN A C 1 ATOM 2438 O O . GLN A 1 316 ? -6.893 61.434 29.424 1.00 51.56 ? 316 GLN A O 1 ATOM 2439 C CB . GLN A 1 316 ? -8.433 62.050 26.749 1.00 48.50 ? 316 GLN A CB 1 ATOM 2440 C CG . GLN A 1 316 ? -8.746 62.071 25.253 1.00 54.01 ? 316 GLN A CG 1 ATOM 2441 C CD . GLN A 1 316 ? -8.779 63.472 24.662 1.00 56.01 ? 316 GLN A CD 1 ATOM 2442 O OE1 . GLN A 1 316 ? -8.046 64.364 25.092 1.00 60.42 ? 316 GLN A OE1 1 ATOM 2443 N NE2 . GLN A 1 316 ? -9.634 63.669 23.664 1.00 59.17 ? 316 GLN A NE2 1 ATOM 2444 N N . HIS A 1 317 ? -6.562 63.610 28.910 1.00 56.10 ? 317 HIS A N 1 ATOM 2445 C CA . HIS A 1 317 ? -6.652 64.098 30.282 1.00 50.37 ? 317 HIS A CA 1 ATOM 2446 C C . HIS A 1 317 ? -8.118 64.402 30.572 1.00 49.38 ? 317 HIS A C 1 ATOM 2447 O O . HIS A 1 317 ? -8.678 65.336 30.001 1.00 59.86 ? 317 HIS A O 1 ATOM 2448 C CB . HIS A 1 317 ? -5.810 65.360 30.467 1.00 61.69 ? 317 HIS A CB 1 ATOM 2449 C CG . HIS A 1 317 ? -4.344 65.146 30.256 1.00 69.72 ? 317 HIS A CG 1 ATOM 2450 N ND1 . HIS A 1 317 ? -3.462 64.960 31.299 1.00 74.07 ? 317 HIS A ND1 1 ATOM 2451 C CD2 . HIS A 1 317 ? -3.606 65.091 29.122 1.00 67.29 ? 317 HIS A CD2 1 ATOM 2452 C CE1 . HIS A 1 317 ? -2.242 64.799 30.817 1.00 76.44 ? 317 HIS A CE1 1 ATOM 2453 N NE2 . HIS A 1 317 ? -2.302 64.874 29.499 1.00 74.07 ? 317 HIS A NE2 1 ATOM 2454 N N . PRO A 1 318 ? -8.749 63.615 31.458 1.00 44.17 ? 318 PRO A N 1 ATOM 2455 C CA . PRO A 1 318 ? -10.188 63.734 31.679 1.00 52.56 ? 318 PRO A CA 1 ATOM 2456 C C . PRO A 1 318 ? -10.540 64.953 32.534 1.00 67.42 ? 318 PRO A C 1 ATOM 2457 O O . PRO A 1 318 ? -9.638 65.586 33.093 1.00 69.71 ? 318 PRO A O 1 ATOM 2458 C CB . PRO A 1 318 ? -10.543 62.440 32.434 1.00 54.63 ? 318 PRO A CB 1 ATOM 2459 C CG . PRO A 1 318 ? -9.275 61.642 32.535 1.00 54.77 ? 318 PRO A CG 1 ATOM 2460 C CD . PRO A 1 318 ? -8.149 62.590 32.325 1.00 52.67 ? 318 PRO A CD 1 ATOM 2461 N N . PRO A 1 319 ? -11.843 65.300 32.622 1.00 72.28 ? 319 PRO A N 1 ATOM 2462 C CA . PRO A 1 319 ? -12.250 66.288 33.621 1.00 70.27 ? 319 PRO A CA 1 ATOM 2463 C C . PRO A 1 319 ? -12.097 65.726 35.036 1.00 63.65 ? 319 PRO A C 1 ATOM 2464 O O . PRO A 1 319 ? -11.783 66.472 35.965 1.00 70.99 ? 319 PRO A O 1 ATOM 2465 C CB . PRO A 1 319 ? -13.733 66.533 33.302 1.00 68.31 ? 319 PRO A CB 1 ATOM 2466 C CG . PRO A 1 319 ? -13.952 65.969 31.935 1.00 71.90 ? 319 PRO A CG 1 ATOM 2467 C CD . PRO A 1 319 ? -12.987 64.839 31.812 1.00 70.70 ? 319 PRO A CD 1 ATOM 2468 N N . GLN A 1 320 ? -12.290 64.415 35.178 1.00 51.87 ? 320 GLN A N 1 ATOM 2469 C CA . GLN A 1 320 ? -12.246 63.736 36.473 1.00 53.46 ? 320 GLN A CA 1 ATOM 2470 C C . GLN A 1 320 ? -10.834 63.649 37.069 1.00 54.74 ? 320 GLN A C 1 ATOM 2471 O O . GLN A 1 320 ? -10.635 63.049 38.129 1.00 55.50 ? 320 GLN A O 1 ATOM 2472 C CB . GLN A 1 320 ? -12.874 62.338 36.373 1.00 57.14 ? 320 GLN A CB 1 ATOM 2473 C CG . GLN A 1 320 ? -14.367 62.317 36.029 1.00 59.15 ? 320 GLN A CG 1 ATOM 2474 C CD . GLN A 1 320 ? -14.654 62.578 34.552 1.00 71.50 ? 320 GLN A CD 1 ATOM 2475 O OE1 . GLN A 1 320 ? -15.679 63.165 34.203 1.00 74.23 ? 320 GLN A OE1 1 ATOM 2476 N NE2 . GLN A 1 320 ? -13.748 62.143 33.680 1.00 69.42 ? 320 GLN A NE2 1 ATOM 2477 N N . SER A 1 321 ? -9.861 64.247 36.384 1.00 51.72 ? 321 SER A N 1 ATOM 2478 C CA . SER A 1 321 ? -8.508 64.397 36.918 1.00 49.63 ? 321 SER A CA 1 ATOM 2479 C C . SER A 1 321 ? -8.398 65.658 37.765 1.00 54.49 ? 321 SER A C 1 ATOM 2480 O O . SER A 1 321 ? -7.341 65.945 38.332 1.00 53.07 ? 321 SER A O 1 ATOM 2481 C CB . SER A 1 321 ? -7.478 64.439 35.788 1.00 55.51 ? 321 SER A CB 1 ATOM 2482 O OG . SER A 1 321 ? -6.959 63.149 35.521 1.00 54.68 ? 321 SER A OG 1 ATOM 2483 N N . THR A 1 322 ? -9.498 66.405 37.841 1.00 63.82 ? 322 THR A N 1 ATOM 2484 C CA . THR A 1 322 ? -9.555 67.648 38.601 1.00 59.45 ? 322 THR A CA 1 ATOM 2485 C C . THR A 1 322 ? -10.774 67.662 39.511 1.00 59.61 ? 322 THR A C 1 ATOM 2486 O O . THR A 1 322 ? -11.910 67.544 39.046 1.00 59.61 ? 322 THR A O 1 ATOM 2487 C CB . THR A 1 322 ? -9.598 68.877 37.676 1.00 55.89 ? 322 THR A CB 1 ATOM 2488 O OG1 . THR A 1 322 ? -8.795 68.623 36.512 1.00 61.04 ? 322 THR A OG1 1 ATOM 2489 C CG2 . THR A 1 322 ? -9.097 70.111 38.423 1.00 63.33 ? 322 THR A CG2 1 ATOM 2490 N N . ALA A 1 323 ? -10.525 67.796 40.810 1.00 63.79 ? 323 ALA A N 1 ATOM 2491 C CA . ALA A 1 323 ? -11.590 67.922 41.799 1.00 63.38 ? 323 ALA A CA 1 ATOM 2492 C C . ALA A 1 323 ? -11.468 69.244 42.549 1.00 60.48 ? 323 ALA A C 1 ATOM 2493 O O . ALA A 1 323 ? -10.428 69.907 42.495 1.00 53.88 ? 323 ALA A O 1 ATOM 2494 C CB . ALA A 1 323 ? -11.568 66.752 42.766 1.00 54.61 ? 323 ALA A CB 1 ATOM 2495 N N . THR A 1 324 ? -12.536 69.617 43.247 1.00 63.96 ? 324 THR A N 1 ATOM 2496 C CA . THR A 1 324 ? -12.584 70.886 43.959 1.00 63.06 ? 324 THR A CA 1 ATOM 2497 C C . THR A 1 324 ? -12.994 70.675 45.411 1.00 62.01 ? 324 THR A C 1 ATOM 2498 O O . THR A 1 324 ? -13.992 70.010 45.696 1.00 59.75 ? 324 THR A O 1 ATOM 2499 C CB . THR A 1 324 ? -13.521 71.886 43.248 1.00 67.31 ? 324 THR A CB 1 ATOM 2500 O OG1 . THR A 1 324 ? -13.283 71.814 41.833 1.00 79.66 ? 324 THR A OG1 1 ATOM 2501 C CG2 . THR A 1 324 ? -13.262 73.309 43.742 1.00 62.72 ? 324 THR A CG2 1 ATOM 2502 N N . VAL A 1 325 ? -12.203 71.235 46.323 1.00 65.13 ? 325 VAL A N 1 ATOM 2503 C CA . VAL A 1 325 ? -12.428 71.065 47.755 1.00 63.83 ? 325 VAL A CA 1 ATOM 2504 C C . VAL A 1 325 ? -12.920 72.359 48.391 1.00 68.61 ? 325 VAL A C 1 ATOM 2505 O O . VAL A 1 325 ? -12.319 73.423 48.211 1.00 61.48 ? 325 VAL A O 1 ATOM 2506 C CB . VAL A 1 325 ? -11.156 70.601 48.493 1.00 56.61 ? 325 VAL A CB 1 ATOM 2507 C CG1 . VAL A 1 325 ? -11.525 69.858 49.766 1.00 55.90 ? 325 VAL A CG1 1 ATOM 2508 C CG2 . VAL A 1 325 ? -10.299 69.728 47.596 1.00 59.88 ? 325 VAL A CG2 1 ATOM 2509 N N . SER A 1 326 ? -14.019 72.248 49.133 1.00 72.87 ? 326 SER A N 1 ATOM 2510 C CA . SER A 1 326 ? -14.602 73.374 49.854 1.00 74.21 ? 326 SER A CA 1 ATOM 2511 C C . SER A 1 326 ? -14.195 73.328 51.325 1.00 77.01 ? 326 SER A C 1 ATOM 2512 O O . SER A 1 326 ? -14.628 72.448 52.073 1.00 74.51 ? 326 SER A O 1 ATOM 2513 C CB . SER A 1 326 ? -16.127 73.363 49.718 1.00 71.67 ? 326 SER A CB 1 ATOM 2514 O OG . SER A 1 326 ? -16.518 73.549 48.368 1.00 66.49 ? 326 SER A OG 1 ATOM 2515 N N . VAL A 1 327 ? -13.356 74.278 51.729 1.00 76.69 ? 327 VAL A N 1 ATOM 2516 C CA . VAL A 1 327 ? -12.852 74.334 53.099 1.00 76.70 ? 327 VAL A CA 1 ATOM 2517 C C . VAL A 1 327 ? -13.687 75.297 53.949 1.00 80.40 ? 327 VAL A C 1 ATOM 2518 O O . VAL A 1 327 ? -13.474 76.514 53.920 1.00 77.27 ? 327 VAL A O 1 ATOM 2519 C CB . VAL A 1 327 ? -11.344 74.720 53.146 1.00 71.26 ? 327 VAL A CB 1 ATOM 2520 C CG1 . VAL A 1 327 ? -10.811 74.647 54.564 1.00 72.80 ? 327 VAL A CG1 1 ATOM 2521 C CG2 . VAL A 1 327 ? -10.522 73.818 52.236 1.00 68.62 ? 327 VAL A CG2 1 ATOM 2522 N N . THR A 1 328 ? -14.648 74.741 54.686 1.00 80.79 ? 328 THR A N 1 ATOM 2523 C CA . THR A 1 328 ? -15.444 75.507 55.643 1.00 76.29 ? 328 THR A CA 1 ATOM 2524 C C . THR A 1 328 ? -14.572 75.794 56.861 1.00 72.68 ? 328 THR A C 1 ATOM 2525 O O . THR A 1 328 ? -13.929 74.887 57.391 1.00 74.35 ? 328 THR A O 1 ATOM 2526 C CB . THR A 1 328 ? -16.726 74.739 56.068 1.00 80.36 ? 328 THR A CB 1 ATOM 2527 O OG1 . THR A 1 328 ? -17.383 74.210 54.910 1.00 79.64 ? 328 THR A OG1 1 ATOM 2528 C CG2 . THR A 1 328 ? -17.692 75.653 56.811 1.00 77.40 ? 328 THR A CG2 1 ATOM 2529 N N . VAL A 1 329 ? -14.536 77.055 57.291 1.00 74.64 ? 329 VAL A N 1 ATOM 2530 C CA . VAL A 1 329 ? -13.682 77.464 58.414 1.00 76.58 ? 329 VAL A CA 1 ATOM 2531 C C . VAL A 1 329 ? -14.482 77.674 59.703 1.00 78.50 ? 329 VAL A C 1 ATOM 2532 O O . VAL A 1 329 ? -15.455 78.432 59.727 1.00 78.30 ? 329 VAL A O 1 ATOM 2533 C CB . VAL A 1 329 ? -12.866 78.745 58.091 1.00 64.57 ? 329 VAL A CB 1 ATOM 2534 C CG1 . VAL A 1 329 ? -11.901 79.065 59.219 1.00 60.38 ? 329 VAL A CG1 1 ATOM 2535 C CG2 . VAL A 1 329 ? -12.110 78.589 56.781 1.00 71.27 ? 329 VAL A CG2 1 ATOM 2536 N N . ILE A 1 330 ? -14.064 76.993 60.768 1.00 77.32 ? 330 ILE A N 1 ATOM 2537 C CA . ILE A 1 330 ? -14.664 77.180 62.089 1.00 81.30 ? 330 ILE A CA 1 ATOM 2538 C C . ILE A 1 330 ? -14.002 78.342 62.835 1.00 86.56 ? 330 ILE A C 1 ATOM 2539 O O . ILE A 1 330 ? -12.779 78.367 63.019 1.00 77.90 ? 330 ILE A O 1 ATOM 2540 C CB . ILE A 1 330 ? -14.661 75.879 62.944 1.00 71.64 ? 330 ILE A CB 1 ATOM 2541 C CG1 . ILE A 1 330 ? -13.343 75.109 62.778 1.00 74.78 ? 330 ILE A CG1 1 ATOM 2542 C CG2 . ILE A 1 330 ? -15.862 75.004 62.577 1.00 65.61 ? 330 ILE A CG2 1 ATOM 2543 C CD1 . ILE A 1 330 ? -13.123 73.989 63.790 1.00 82.52 ? 330 ILE A CD1 1 ATOM 2544 N N . ASP A 1 331 ? -14.830 79.309 63.236 1.00 89.09 ? 331 ASP A N 1 ATOM 2545 C CA . ASP A 1 331 ? -14.382 80.524 63.925 1.00 87.19 ? 331 ASP A CA 1 ATOM 2546 C C . ASP A 1 331 ? -14.233 80.300 65.430 1.00 85.69 ? 331 ASP A C 1 ATOM 2547 O O . ASP A 1 331 ? -15.093 79.684 66.065 1.00 81.53 ? 331 ASP A O 1 ATOM 2548 C CB . ASP A 1 331 ? -15.360 81.679 63.652 1.00 86.70 ? 331 ASP A CB 1 ATOM 2549 C CG . ASP A 1 331 ? -14.982 82.970 64.379 1.00 84.82 ? 331 ASP A CG 1 ATOM 2550 O OD1 . ASP A 1 331 ? -13.773 83.269 64.515 1.00 84.17 ? 331 ASP A OD1 1 ATOM 2551 O OD2 . ASP A 1 331 ? -15.906 83.694 64.806 1.00 82.14 ? 331 ASP A OD2 1 ATOM 2552 N N . VAL A 1 332 ? -13.138 80.809 65.990 1.00 80.50 ? 332 VAL A N 1 ATOM 2553 C CA . VAL A 1 332 ? -12.885 80.700 67.427 1.00 91.16 ? 332 VAL A CA 1 ATOM 2554 C C . VAL A 1 332 ? -12.909 82.061 68.123 1.00 92.54 ? 332 VAL A C 1 ATOM 2555 O O . VAL A 1 332 ? -12.632 83.092 67.502 1.00 83.61 ? 332 VAL A O 1 ATOM 2556 C CB . VAL A 1 332 ? -11.552 79.957 67.743 1.00 92.43 ? 332 VAL A CB 1 ATOM 2557 C CG1 . VAL A 1 332 ? -11.679 78.465 67.441 1.00 78.40 ? 332 VAL A CG1 1 ATOM 2558 C CG2 . VAL A 1 332 ? -10.375 80.575 66.987 1.00 87.69 ? 332 VAL A CG2 1 ATOM 2559 N N . ASN A 1 333 ? -13.254 82.046 69.411 1.00 95.42 ? 333 ASN A N 1 ATOM 2560 C CA . ASN A 1 333 ? -13.275 83.249 70.239 1.00 97.58 ? 333 ASN A CA 1 ATOM 2561 C C . ASN A 1 333 ? -11.853 83.714 70.552 1.00 93.64 ? 333 ASN A C 1 ATOM 2562 O O . ASN A 1 333 ? -10.982 82.896 70.856 1.00 93.09 ? 333 ASN A O 1 ATOM 2563 C CB . ASN A 1 333 ? -14.054 82.981 71.533 1.00 104.96 ? 333 ASN A CB 1 ATOM 2564 C CG . ASN A 1 333 ? -14.547 84.256 72.210 1.00 105.45 ? 333 ASN A CG 1 ATOM 2565 O OD1 . ASN A 1 333 ? -14.250 85.371 71.773 1.00 104.05 ? 333 ASN A OD1 1 ATOM 2566 N ND2 . ASN A 1 333 ? -15.308 84.091 73.287 1.00 111.35 ? 333 ASN A ND2 1 ATOM 2567 N N . GLU A 1 334 ? -11.622 85.025 70.469 1.00 93.64 ? 334 GLU A N 1 ATOM 2568 C CA . GLU A 1 334 ? -10.278 85.593 70.634 1.00 93.81 ? 334 GLU A CA 1 ATOM 2569 C C . GLU A 1 334 ? -10.238 86.808 71.568 1.00 94.65 ? 334 GLU A C 1 ATOM 2570 O O . GLU A 1 334 ? -11.252 87.482 71.771 1.00 89.81 ? 334 GLU A O 1 ATOM 2571 C CB . GLU A 1 334 ? -9.675 85.940 69.266 1.00 90.91 ? 334 GLU A CB 1 ATOM 2572 C CG . GLU A 1 334 ? -9.125 84.731 68.509 1.00 93.45 ? 334 GLU A CG 1 ATOM 2573 C CD . GLU A 1 334 ? -9.288 84.843 67.001 1.00 84.08 ? 334 GLU A CD 1 ATOM 2574 O OE1 . GLU A 1 334 ? -8.710 85.764 66.387 1.00 76.98 ? 334 GLU A OE1 1 ATOM 2575 O OE2 . GLU A 1 334 ? -10.001 83.999 66.421 1.00 79.38 ? 334 GLU A OE2 1 ATOM 2576 N N . ASN A 1 335 ? -9.054 87.072 72.123 1.00 94.99 ? 335 ASN A N 1 ATOM 2577 C CA . ASN A 1 335 ? -8.842 88.143 73.102 1.00 87.23 ? 335 ASN A CA 1 ATOM 2578 C C . ASN A 1 335 ? -9.191 89.536 72.584 1.00 93.83 ? 335 ASN A C 1 ATOM 2579 O O . ASN A 1 335 ? -8.898 89.859 71.432 1.00 96.08 ? 335 ASN A O 1 ATOM 2580 C CB . ASN A 1 335 ? -7.388 88.146 73.590 1.00 82.11 ? 335 ASN A CB 1 ATOM 2581 C CG . ASN A 1 335 ? -6.971 86.826 74.204 1.00 86.76 ? 335 ASN A CG 1 ATOM 2582 O OD1 . ASN A 1 335 ? -6.071 86.156 73.700 1.00 85.02 ? 335 ASN A OD1 1 ATOM 2583 N ND2 . ASN A 1 335 ? -7.622 86.443 75.296 1.00 90.66 ? 335 ASN A ND2 1 ATOM 2584 N N . PRO A 1 336 ? -9.835 90.362 73.430 1.00 96.08 ? 336 PRO A N 1 ATOM 2585 C CA . PRO A 1 336 ? -9.995 91.773 73.098 1.00 90.70 ? 336 PRO A CA 1 ATOM 2586 C C . PRO A 1 336 ? -8.762 92.589 73.484 1.00 85.52 ? 336 PRO A C 1 ATOM 2587 O O . PRO A 1 336 ? -8.045 92.229 74.423 1.00 78.82 ? 336 PRO A O 1 ATOM 2588 C CB . PRO A 1 336 ? -11.200 92.192 73.938 1.00 84.79 ? 336 PRO A CB 1 ATOM 2589 C CG . PRO A 1 336 ? -11.176 91.285 75.116 1.00 85.19 ? 336 PRO A CG 1 ATOM 2590 C CD . PRO A 1 336 ? -10.471 90.018 74.717 1.00 89.23 ? 336 PRO A CD 1 ATOM 2591 N N . TYR A 1 337 ? -8.514 93.671 72.752 1.00 93.79 ? 337 TYR A N 1 ATOM 2592 C CA . TYR A 1 337 ? -7.398 94.567 73.063 1.00 100.37 ? 337 TYR A CA 1 ATOM 2593 C C . TYR A 1 337 ? -7.755 96.052 72.898 1.00 108.04 ? 337 TYR A C 1 ATOM 2594 O O . TYR A 1 337 ? -8.911 96.394 72.647 1.00 105.19 ? 337 TYR A O 1 ATOM 2595 C CB . TYR A 1 337 ? -6.113 94.159 72.313 1.00 96.13 ? 337 TYR A CB 1 ATOM 2596 C CG . TYR A 1 337 ? -6.105 94.359 70.806 1.00 97.43 ? 337 TYR A CG 1 ATOM 2597 C CD1 . TYR A 1 337 ? -7.065 93.760 69.985 1.00 97.63 ? 337 TYR A CD1 1 ATOM 2598 C CD2 . TYR A 1 337 ? -5.102 95.116 70.197 1.00 104.66 ? 337 TYR A CD2 1 ATOM 2599 C CE1 . TYR A 1 337 ? -7.042 93.938 68.600 1.00 103.67 ? 337 TYR A CE1 1 ATOM 2600 C CE2 . TYR A 1 337 ? -5.069 95.297 68.815 1.00 105.46 ? 337 TYR A CE2 1 ATOM 2601 C CZ . TYR A 1 337 ? -6.040 94.706 68.025 1.00 105.94 ? 337 TYR A CZ 1 ATOM 2602 O OH . TYR A 1 337 ? -6.005 94.883 66.660 1.00 108.82 ? 337 TYR A OH 1 ATOM 2603 N N . PHE A 1 338 ? -6.751 96.916 73.030 1.00 109.79 ? 338 PHE A N 1 ATOM 2604 C CA . PHE A 1 338 ? -6.947 98.341 73.309 1.00 109.72 ? 338 PHE A CA 1 ATOM 2605 C C . PHE A 1 338 ? -6.091 99.226 72.405 1.00 111.20 ? 338 PHE A C 1 ATOM 2606 O O . PHE A 1 338 ? -4.950 98.874 72.097 1.00 111.18 ? 338 PHE A O 1 ATOM 2607 C CB . PHE A 1 338 ? -6.590 98.593 74.776 1.00 113.26 ? 338 PHE A CB 1 ATOM 2608 C CG . PHE A 1 338 ? -5.747 97.500 75.377 1.00 112.57 ? 338 PHE A CG 1 ATOM 2609 C CD1 . PHE A 1 338 ? -4.373 97.463 75.158 1.00 116.48 ? 338 PHE A CD1 1 ATOM 2610 C CD2 . PHE A 1 338 ? -6.334 96.483 76.126 1.00 112.91 ? 338 PHE A CD2 1 ATOM 2611 C CE1 . PHE A 1 338 ? -3.595 96.442 75.692 1.00 123.83 ? 338 PHE A CE1 1 ATOM 2612 C CE2 . PHE A 1 338 ? -5.562 95.457 76.663 1.00 114.73 ? 338 PHE A CE2 1 ATOM 2613 C CZ . PHE A 1 338 ? -4.189 95.438 76.447 1.00 120.17 ? 338 PHE A CZ 1 ATOM 2614 N N . ALA A 1 339 ? -6.640 100.374 71.998 1.00 115.99 ? 339 ALA A N 1 ATOM 2615 C CA . ALA A 1 339 ? -5.959 101.294 71.068 1.00 124.37 ? 339 ALA A CA 1 ATOM 2616 C C . ALA A 1 339 ? -4.536 101.674 71.522 1.00 126.74 ? 339 ALA A C 1 ATOM 2617 O O . ALA A 1 339 ? -3.572 101.400 70.802 1.00 126.10 ? 339 ALA A O 1 ATOM 2618 C CB . ALA A 1 339 ? -6.821 102.536 70.777 1.00 115.60 ? 339 ALA A CB 1 ATOM 2619 N N . PRO A 1 340 ? -4.397 102.326 72.696 1.00 123.05 ? 340 PRO A N 1 ATOM 2620 C CA . PRO A 1 340 ? -3.085 102.331 73.338 1.00 118.45 ? 340 PRO A CA 1 ATOM 2621 C C . PRO A 1 340 ? -2.981 101.217 74.384 1.00 112.22 ? 340 PRO A C 1 ATOM 2622 O O . PRO A 1 340 ? -3.983 100.864 75.013 1.00 106.56 ? 340 PRO A O 1 ATOM 2623 C CB . PRO A 1 340 ? -3.037 103.706 74.017 1.00 111.92 ? 340 PRO A CB 1 ATOM 2624 C CG . PRO A 1 340 ? -4.486 104.227 74.011 1.00 108.55 ? 340 PRO A CG 1 ATOM 2625 C CD . PRO A 1 340 ? -5.359 103.143 73.457 1.00 111.28 ? 340 PRO A CD 1 ATOM 2626 N N . ASN A 1 341 ? -1.787 100.659 74.563 1.00 110.78 ? 341 ASN A N 1 ATOM 2627 C CA . ASN A 1 341 ? -1.592 99.637 75.591 1.00 111.94 ? 341 ASN A CA 1 ATOM 2628 C C . ASN A 1 341 ? -1.463 100.222 77.001 1.00 118.07 ? 341 ASN A C 1 ATOM 2629 O O . ASN A 1 341 ? -2.298 99.924 77.858 1.00 121.07 ? 341 ASN A O 1 ATOM 2630 C CB . ASN A 1 341 ? -0.431 98.688 75.254 1.00 121.39 ? 341 ASN A CB 1 ATOM 2631 C CG . ASN A 1 341 ? 0.046 97.887 76.463 1.00 126.52 ? 341 ASN A CG 1 ATOM 2632 O OD1 . ASN A 1 341 ? 1.216 97.960 76.840 1.00 134.32 ? 341 ASN A OD1 1 ATOM 2633 N ND2 . ASN A 1 341 ? -0.861 97.134 77.084 1.00 118.68 ? 341 ASN A ND2 1 ATOM 2634 N N . PRO A 1 342 ? -0.414 101.037 77.256 1.00 118.54 ? 342 PRO A N 1 ATOM 2635 C CA . PRO A 1 342 ? -0.363 101.740 78.526 1.00 109.12 ? 342 PRO A CA 1 ATOM 2636 C C . PRO A 1 342 ? -0.867 103.180 78.367 1.00 108.92 ? 342 PRO A C 1 ATOM 2637 O O . PRO A 1 342 ? -0.064 104.112 78.255 1.00 119.38 ? 342 PRO A O 1 ATOM 2638 C CB . PRO A 1 342 ? 1.133 101.711 78.868 1.00 108.76 ? 342 PRO A CB 1 ATOM 2639 C CG . PRO A 1 342 ? 1.853 101.481 77.520 1.00 117.13 ? 342 PRO A CG 1 ATOM 2640 C CD . PRO A 1 342 ? 0.790 101.334 76.459 1.00 119.07 ? 342 PRO A CD 1 ATOM 2641 N N . LYS A 1 343 ? -2.191 103.340 78.345 1.00 102.66 ? 343 LYS A N 1 ATOM 2642 C CA . LYS A 1 343 ? -2.841 104.644 78.163 1.00 96.48 ? 343 LYS A CA 1 ATOM 2643 C C . LYS A 1 343 ? -2.244 105.721 79.078 1.00 99.69 ? 343 LYS A C 1 ATOM 2644 O O . LYS A 1 343 ? -2.455 105.710 80.294 1.00 105.05 ? 343 LYS A O 1 ATOM 2645 C CB . LYS A 1 343 ? -4.360 104.510 78.372 1.00 87.76 ? 343 LYS A CB 1 ATOM 2646 C CG . LYS A 1 343 ? -5.164 105.813 78.310 1.00 86.66 ? 343 LYS A CG 1 ATOM 2647 C CD . LYS A 1 343 ? -5.384 106.302 76.885 1.00 91.69 ? 343 LYS A CD 1 ATOM 2648 C CE . LYS A 1 343 ? -6.282 107.527 76.860 1.00 94.96 ? 343 LYS A CE 1 ATOM 2649 N NZ . LYS A 1 343 ? -6.441 108.077 75.489 1.00 77.40 ? 343 LYS A NZ 1 ATOM 2650 N N . ILE A 1 344 ? -1.482 106.633 78.478 1.00 96.26 ? 344 ILE A N 1 ATOM 2651 C CA . ILE A 1 344 ? -0.850 107.728 79.214 1.00 95.98 ? 344 ILE A CA 1 ATOM 2652 C C . ILE A 1 344 ? -1.711 108.990 79.182 1.00 103.94 ? 344 ILE A C 1 ATOM 2653 O O . ILE A 1 344 ? -2.099 109.464 78.110 1.00 105.37 ? 344 ILE A O 1 ATOM 2654 C CB . ILE A 1 344 ? 0.585 108.037 78.702 1.00 99.16 ? 344 ILE A CB 1 ATOM 2655 C CG1 . ILE A 1 344 ? 0.623 108.101 77.166 1.00 109.32 ? 344 ILE A CG1 1 ATOM 2656 C CG2 . ILE A 1 344 ? 1.572 106.999 79.233 1.00 86.52 ? 344 ILE A CG2 1 ATOM 2657 C CD1 . ILE A 1 344 ? 1.669 109.053 76.599 1.00 104.66 ? 344 ILE A CD1 1 ATOM 2658 N N . ILE A 1 345 ? -2.018 109.514 80.367 1.00 106.01 ? 345 ILE A N 1 ATOM 2659 C CA . ILE A 1 345 ? -2.830 110.724 80.510 1.00 109.68 ? 345 ILE A CA 1 ATOM 2660 C C . ILE A 1 345 ? -2.224 111.670 81.550 1.00 104.08 ? 345 ILE A C 1 ATOM 2661 O O . ILE A 1 345 ? -1.883 111.253 82.658 1.00 100.33 ? 345 ILE A O 1 ATOM 2662 C CB . ILE A 1 345 ? -4.325 110.382 80.839 1.00 104.49 ? 345 ILE A CB 1 ATOM 2663 C CG1 . ILE A 1 345 ? -5.087 109.957 79.571 1.00 105.48 ? 345 ILE A CG1 1 ATOM 2664 C CG2 . ILE A 1 345 ? -5.043 111.544 81.539 1.00 105.35 ? 345 ILE A CG2 1 ATOM 2665 C CD1 . ILE A 1 345 ? -5.239 111.041 78.487 1.00 96.73 ? 345 ILE A CD1 1 ATOM 2666 N N . ARG A 1 346 ? -2.075 112.937 81.170 1.00 105.75 ? 346 ARG A N 1 ATOM 2667 C CA . ARG A 1 346 ? -1.597 113.977 82.078 1.00 106.02 ? 346 ARG A CA 1 ATOM 2668 C C . ARG A 1 346 ? -2.763 114.567 82.875 1.00 113.44 ? 346 ARG A C 1 ATOM 2669 O O . ARG A 1 346 ? -3.804 114.902 82.303 1.00 115.57 ? 346 ARG A O 1 ATOM 2670 C CB . ARG A 1 346 ? -0.871 115.076 81.297 1.00 99.99 ? 346 ARG A CB 1 ATOM 2671 C CG . ARG A 1 346 ? 0.515 114.682 80.794 1.00 95.52 ? 346 ARG A CG 1 ATOM 2672 C CD . ARG A 1 346 ? 1.220 115.847 80.106 1.00 100.69 ? 346 ARG A CD 1 ATOM 2673 N NE . ARG A 1 346 ? 1.387 117.000 80.994 1.00 106.89 ? 346 ARG A NE 1 ATOM 2674 C CZ . ARG A 1 346 ? 2.005 118.132 80.665 1.00 102.97 ? 346 ARG A CZ 1 ATOM 2675 N NH1 . ARG A 1 346 ? 2.536 118.288 79.459 1.00 108.62 ? 346 ARG A NH1 1 ATOM 2676 N NH2 . ARG A 1 346 ? 2.096 119.114 81.550 1.00 90.23 ? 346 ARG A NH2 1 ATOM 2677 N N . GLN A 1 347 ? -2.585 114.687 84.192 1.00 108.23 ? 347 GLN A N 1 ATOM 2678 C CA . GLN A 1 347 ? -3.632 115.202 85.082 1.00 106.33 ? 347 GLN A CA 1 ATOM 2679 C C . GLN A 1 347 ? -3.051 115.944 86.291 1.00 109.48 ? 347 GLN A C 1 ATOM 2680 O O . GLN A 1 347 ? -2.123 115.455 86.938 1.00 105.95 ? 347 GLN A O 1 ATOM 2681 C CB . GLN A 1 347 ? -4.544 114.058 85.546 1.00 96.59 ? 347 GLN A CB 1 ATOM 2682 C CG . GLN A 1 347 ? -5.785 114.488 86.335 1.00 106.08 ? 347 GLN A CG 1 ATOM 2683 C CD . GLN A 1 347 ? -6.812 115.225 85.487 1.00 115.09 ? 347 GLN A CD 1 ATOM 2684 O OE1 . GLN A 1 347 ? -7.115 116.391 85.740 1.00 120.53 ? 347 GLN A OE1 1 ATOM 2685 N NE2 . GLN A 1 347 ? -7.350 114.548 84.478 1.00 111.11 ? 347 GLN A NE2 1 ATOM 2686 N N . GLU A 1 348 ? -3.603 117.122 86.586 1.00 108.75 ? 348 GLU A N 1 ATOM 2687 C CA . GLU A 1 348 ? -3.208 117.882 87.771 1.00 103.28 ? 348 GLU A CA 1 ATOM 2688 C C . GLU A 1 348 ? -3.635 117.088 89.012 1.00 100.45 ? 348 GLU A C 1 ATOM 2689 O O . GLU A 1 348 ? -4.495 116.208 88.930 1.00 104.65 ? 348 GLU A O 1 ATOM 2690 C CB . GLU A 1 348 ? -3.700 119.343 87.719 1.00 110.52 ? 348 GLU A CB 1 ATOM 2691 C CG . GLU A 1 348 ? -5.188 119.538 87.419 1.00 124.05 ? 348 GLU A CG 1 ATOM 2692 C CD . GLU A 1 348 ? -5.451 120.014 85.996 1.00 129.42 ? 348 GLU A CD 1 ATOM 2693 O OE1 . GLU A 1 348 ? -4.972 121.110 85.630 1.00 115.97 ? 348 GLU A OE1 1 ATOM 2694 O OE2 . GLU A 1 348 ? -6.154 119.300 85.248 1.00 127.50 ? 348 GLU A OE2 1 ATOM 2695 N N . GLU A 1 349 ? -3.025 117.416 90.150 1.00 99.49 ? 349 GLU A N 1 ATOM 2696 C CA . GLU A 1 349 ? -3.102 116.602 91.362 1.00 94.07 ? 349 GLU A CA 1 ATOM 2697 C C . GLU A 1 349 ? -4.490 116.709 92.026 1.00 96.26 ? 349 GLU A C 1 ATOM 2698 O O . GLU A 1 349 ? -5.282 115.767 91.958 1.00 97.99 ? 349 GLU A O 1 ATOM 2699 C CB . GLU A 1 349 ? -2.011 116.972 92.373 1.00 84.78 ? 349 GLU A CB 1 ATOM 2700 C CG . GLU A 1 349 ? -1.659 115.848 93.326 1.00 84.59 ? 349 GLU A CG 1 ATOM 2701 C CD . GLU A 1 349 ? -0.840 116.306 94.514 1.00 90.00 ? 349 GLU A CD 1 ATOM 2702 O OE1 . GLU A 1 349 ? -0.128 117.330 94.417 1.00 86.78 ? 349 GLU A OE1 1 ATOM 2703 O OE2 . GLU A 1 349 ? -0.908 115.632 95.561 1.00 93.40 ? 349 GLU A OE2 1 ATOM 2704 N N . GLY A 1 350 ? -4.765 117.847 92.662 1.00 99.47 ? 350 GLY A N 1 ATOM 2705 C CA . GLY A 1 350 ? -6.030 118.068 93.363 1.00 99.37 ? 350 GLY A CA 1 ATOM 2706 C C . GLY A 1 350 ? -7.222 118.103 92.427 1.00 107.41 ? 350 GLY A C 1 ATOM 2707 O O . GLY A 1 350 ? -7.381 119.041 91.643 1.00 111.06 ? 350 GLY A O 1 ATOM 2708 N N . LEU A 1 351 ? -8.058 117.071 92.508 1.00 103.64 ? 351 LEU A N 1 ATOM 2709 C CA . LEU A 1 351 ? -9.236 116.964 91.655 1.00 106.50 ? 351 LEU A CA 1 ATOM 2710 C C . LEU A 1 351 ? -10.409 116.346 92.407 1.00 107.19 ? 351 LEU A C 1 ATOM 2711 O O . LEU A 1 351 ? -10.221 115.474 93.260 1.00 107.22 ? 351 LEU A O 1 ATOM 2712 C CB . LEU A 1 351 ? -8.913 116.148 90.398 1.00 116.26 ? 351 LEU A CB 1 ATOM 2713 C CG . LEU A 1 351 ? -9.782 116.348 89.150 1.00 122.64 ? 351 LEU A CG 1 ATOM 2714 C CD1 . LEU A 1 351 ? -9.583 117.734 88.533 1.00 112.98 ? 351 LEU A CD1 1 ATOM 2715 C CD2 . LEU A 1 351 ? -9.491 115.261 88.125 1.00 118.74 ? 351 LEU A CD2 1 ATOM 2716 N N . HIS A 1 352 ? -11.615 116.810 92.077 1.00 110.07 ? 352 HIS A N 1 ATOM 2717 C CA . HIS A 1 352 ? -12.857 116.342 92.697 1.00 115.20 ? 352 HIS A CA 1 ATOM 2718 C C . HIS A 1 352 ? -13.040 114.828 92.633 1.00 117.68 ? 352 HIS A C 1 ATOM 2719 O O . HIS A 1 352 ? -12.477 114.153 91.767 1.00 117.32 ? 352 HIS A O 1 ATOM 2720 C CB . HIS A 1 352 ? -14.072 117.020 92.049 1.00 119.72 ? 352 HIS A CB 1 ATOM 2721 C CG . HIS A 1 352 ? -14.556 118.237 92.777 1.00 130.73 ? 352 HIS A CG 1 ATOM 2722 N ND1 . HIS A 1 352 ? -15.149 118.174 94.021 1.00 123.63 ? 352 HIS A ND1 1 ATOM 2723 C CD2 . HIS A 1 352 ? -14.556 119.546 92.426 1.00 130.49 ? 352 HIS A CD2 1 ATOM 2724 C CE1 . HIS A 1 352 ? -15.481 119.392 94.410 1.00 127.52 ? 352 HIS A CE1 1 ATOM 2725 N NE2 . HIS A 1 352 ? -15.133 120.243 93.461 1.00 126.22 ? 352 HIS A NE2 1 ATOM 2726 N N . ALA A 1 353 ? -13.829 114.307 93.569 1.00 114.73 ? 353 ALA A N 1 ATOM 2727 C CA . ALA A 1 353 ? -14.260 112.920 93.532 1.00 109.84 ? 353 ALA A CA 1 ATOM 2728 C C . ALA A 1 353 ? -15.522 112.822 92.674 1.00 119.48 ? 353 ALA A C 1 ATOM 2729 O O . ALA A 1 353 ? -16.611 113.223 93.097 1.00 118.70 ? 353 ALA A O 1 ATOM 2730 C CB . ALA A 1 353 ? -14.514 112.406 94.941 1.00 108.54 ? 353 ALA A CB 1 ATOM 2731 N N . GLY A 1 354 ? -15.358 112.309 91.457 1.00 119.43 ? 354 GLY A N 1 ATOM 2732 C CA . GLY A 1 354 ? -16.461 112.189 90.505 1.00 115.83 ? 354 GLY A CA 1 ATOM 2733 C C . GLY A 1 354 ? -16.172 112.809 89.148 1.00 115.77 ? 354 GLY A C 1 ATOM 2734 O O . GLY A 1 354 ? -17.060 112.886 88.296 1.00 115.51 ? 354 GLY A O 1 ATOM 2735 N N . THR A 1 355 ? -14.932 113.251 88.949 1.00 114.04 ? 355 THR A N 1 ATOM 2736 C CA . THR A 1 355 ? -14.507 113.835 87.678 1.00 116.78 ? 355 THR A CA 1 ATOM 2737 C C . THR A 1 355 ? -14.149 112.730 86.686 1.00 121.03 ? 355 THR A C 1 ATOM 2738 O O . THR A 1 355 ? -13.402 111.807 87.019 1.00 122.66 ? 355 THR A O 1 ATOM 2739 C CB . THR A 1 355 ? -13.293 114.779 87.861 1.00 117.89 ? 355 THR A CB 1 ATOM 2740 O OG1 . THR A 1 355 ? -13.527 115.661 88.967 1.00 126.02 ? 355 THR A OG1 1 ATOM 2741 C CG2 . THR A 1 355 ? -13.042 115.605 86.599 1.00 112.56 ? 355 THR A CG2 1 ATOM 2742 N N . MET A 1 356 ? -14.694 112.828 85.475 1.00 123.33 ? 356 MET A N 1 ATOM 2743 C CA . MET A 1 356 ? -14.375 111.891 84.398 1.00 121.99 ? 356 MET A CA 1 ATOM 2744 C C . MET A 1 356 ? -13.011 112.242 83.800 1.00 122.47 ? 356 MET A C 1 ATOM 2745 O O . MET A 1 356 ? -12.863 113.270 83.132 1.00 126.10 ? 356 MET A O 1 ATOM 2746 C CB . MET A 1 356 ? -15.478 111.913 83.330 1.00 121.71 ? 356 MET A CB 1 ATOM 2747 C CG . MET A 1 356 ? -15.458 110.736 82.351 1.00 128.93 ? 356 MET A CG 1 ATOM 2748 S SD . MET A 1 356 ? -14.567 111.046 80.806 1.00 140.93 ? 356 MET A SD 1 ATOM 2749 C CE . MET A 1 356 ? -15.709 112.125 79.938 1.00 124.17 ? 356 MET A CE 1 ATOM 2750 N N . LEU A 1 357 ? -12.017 111.393 84.060 1.00 114.95 ? 357 LEU A N 1 ATOM 2751 C CA . LEU A 1 357 ? -10.646 111.630 83.600 1.00 112.76 ? 357 LEU A CA 1 ATOM 2752 C C . LEU A 1 357 ? -10.532 111.374 82.104 1.00 121.83 ? 357 LEU A C 1 ATOM 2753 O O . LEU A 1 357 ? -10.352 112.304 81.314 1.00 114.00 ? 357 LEU A O 1 ATOM 2754 C CB . LEU A 1 357 ? -9.639 110.741 84.343 1.00 98.55 ? 357 LEU A CB 1 ATOM 2755 C CG . LEU A 1 357 ? -9.685 110.583 85.861 1.00 97.70 ? 357 LEU A CG 1 ATOM 2756 C CD1 . LEU A 1 357 ? -10.526 109.376 86.245 1.00 97.24 ? 357 LEU A CD1 1 ATOM 2757 C CD2 . LEU A 1 357 ? -8.275 110.428 86.394 1.00 95.35 ? 357 LEU A CD2 1 ATOM 2758 N N . THR A 1 358 ? -10.639 110.099 81.733 1.00 126.22 ? 358 THR A N 1 ATOM 2759 C CA . THR A 1 358 ? -10.554 109.661 80.342 1.00 120.63 ? 358 THR A CA 1 ATOM 2760 C C . THR A 1 358 ? -11.304 108.339 80.149 1.00 118.85 ? 358 THR A C 1 ATOM 2761 O O . THR A 1 358 ? -11.533 107.596 81.110 1.00 110.05 ? 358 THR A O 1 ATOM 2762 C CB . THR A 1 358 ? -9.077 109.540 79.862 1.00 114.74 ? 358 THR A CB 1 ATOM 2763 O OG1 . THR A 1 358 ? -9.045 109.206 78.468 1.00 114.07 ? 358 THR A OG1 1 ATOM 2764 C CG2 . THR A 1 358 ? -8.308 108.486 80.668 1.00 101.09 ? 358 THR A CG2 1 ATOM 2765 N N . THR A 1 359 ? -11.692 108.065 78.906 1.00 122.66 ? 359 THR A N 1 ATOM 2766 C CA . THR A 1 359 ? -12.374 106.820 78.558 1.00 114.66 ? 359 THR A CA 1 ATOM 2767 C C . THR A 1 359 ? -11.373 105.816 77.984 1.00 113.38 ? 359 THR A C 1 ATOM 2768 O O . THR A 1 359 ? -10.447 106.200 77.263 1.00 116.22 ? 359 THR A O 1 ATOM 2769 C CB . THR A 1 359 ? -13.506 107.064 77.537 1.00 110.68 ? 359 THR A CB 1 ATOM 2770 O OG1 . THR A 1 359 ? -12.963 107.642 76.345 1.00 114.31 ? 359 THR A OG1 1 ATOM 2771 C CG2 . THR A 1 359 ? -14.550 108.010 78.107 1.00 110.96 ? 359 THR A CG2 1 ATOM 2772 N N . LEU A 1 360 ? -11.553 104.537 78.315 1.00 113.73 ? 360 LEU A N 1 ATOM 2773 C CA . LEU A 1 360 ? -10.682 103.472 77.804 1.00 112.69 ? 360 LEU A CA 1 ATOM 2774 C C . LEU A 1 360 ? -11.298 102.713 76.630 1.00 115.45 ? 360 LEU A C 1 ATOM 2775 O O . LEU A 1 360 ? -12.311 102.022 76.780 1.00 115.69 ? 360 LEU A O 1 ATOM 2776 C CB . LEU A 1 360 ? -10.280 102.494 78.915 1.00 98.28 ? 360 LEU A CB 1 ATOM 2777 C CG . LEU A 1 360 ? -9.000 102.778 79.707 1.00 91.96 ? 360 LEU A CG 1 ATOM 2778 C CD1 . LEU A 1 360 ? -8.824 101.731 80.793 1.00 87.12 ? 360 LEU A CD1 1 ATOM 2779 C CD2 . LEU A 1 360 ? -7.767 102.826 78.808 1.00 91.56 ? 360 LEU A CD2 1 ATOM 2780 N N . THR A 1 361 ? -10.670 102.849 75.464 1.00 115.28 ? 361 THR A N 1 ATOM 2781 C CA . THR A 1 361 ? -11.121 102.172 74.250 1.00 113.69 ? 361 THR A CA 1 ATOM 2782 C C . THR A 1 361 ? -10.588 100.743 74.189 1.00 112.11 ? 361 THR A C 1 ATOM 2783 O O . THR A 1 361 ? -9.408 100.494 74.456 1.00 110.95 ? 361 THR A O 1 ATOM 2784 C CB . THR A 1 361 ? -10.704 102.935 72.966 1.00 114.32 ? 361 THR A CB 1 ATOM 2785 O OG1 . THR A 1 361 ? -9.305 103.246 73.017 1.00 112.45 ? 361 THR A OG1 1 ATOM 2786 C CG2 . THR A 1 361 ? -11.507 104.224 72.812 1.00 104.98 ? 361 THR A CG2 1 ATOM 2787 N N . ALA A 1 362 ? -11.474 99.811 73.850 1.00 111.66 ? 362 ALA A N 1 ATOM 2788 C CA . ALA A 1 362 ? -11.106 98.414 73.654 1.00 109.22 ? 362 ALA A CA 1 ATOM 2789 C C . ALA A 1 362 ? -11.930 97.788 72.531 1.00 103.04 ? 362 ALA A C 1 ATOM 2790 O O . ALA A 1 362 ? -13.148 97.979 72.460 1.00 100.62 ? 362 ALA A O 1 ATOM 2791 C CB . ALA A 1 362 ? -11.264 97.625 74.948 1.00 104.95 ? 362 ALA A CB 1 ATOM 2792 N N . GLN A 1 363 ? -11.253 97.049 71.656 1.00 103.92 ? 363 GLN A N 1 ATOM 2793 C CA . GLN A 1 363 ? -11.889 96.421 70.496 1.00 110.24 ? 363 GLN A CA 1 ATOM 2794 C C . GLN A 1 363 ? -11.592 94.919 70.393 1.00 106.57 ? 363 GLN A C 1 ATOM 2795 O O . GLN A 1 363 ? -10.771 94.384 71.145 1.00 99.13 ? 363 GLN A O 1 ATOM 2796 C CB . GLN A 1 363 ? -11.501 97.149 69.201 1.00 110.47 ? 363 GLN A CB 1 ATOM 2797 C CG . GLN A 1 363 ? -9.998 97.236 68.937 1.00 108.13 ? 363 GLN A CG 1 ATOM 2798 C CD . GLN A 1 363 ? -9.667 97.920 67.623 1.00 113.46 ? 363 GLN A CD 1 ATOM 2799 O OE1 . GLN A 1 363 ? -10.400 98.797 67.158 1.00 111.32 ? 363 GLN A OE1 1 ATOM 2800 N NE2 . GLN A 1 363 ? -8.554 97.524 67.018 1.00 110.46 ? 363 GLN A NE2 1 ATOM 2801 N N . ASP A 1 364 ? -12.265 94.258 69.452 1.00 111.82 ? 364 ASP A N 1 ATOM 2802 C CA . ASP A 1 364 ? -12.206 92.805 69.299 1.00 107.25 ? 364 ASP A CA 1 ATOM 2803 C C . ASP A 1 364 ? -12.071 92.413 67.820 1.00 104.24 ? 364 ASP A C 1 ATOM 2804 O O . ASP A 1 364 ? -12.735 93.005 66.965 1.00 98.50 ? 364 ASP A O 1 ATOM 2805 C CB . ASP A 1 364 ? -13.471 92.180 69.900 1.00 95.94 ? 364 ASP A CB 1 ATOM 2806 C CG . ASP A 1 364 ? -13.289 90.725 70.277 1.00 93.37 ? 364 ASP A CG 1 ATOM 2807 O OD1 . ASP A 1 364 ? -12.369 90.411 71.062 1.00 91.79 ? 364 ASP A OD1 1 ATOM 2808 O OD2 . ASP A 1 364 ? -14.084 89.887 69.804 1.00 97.06 ? 364 ASP A OD2 1 ATOM 2809 N N . PRO A 1 365 ? -11.199 91.426 67.511 1.00 100.16 ? 365 PRO A N 1 ATOM 2810 C CA . PRO A 1 365 ? -11.020 90.948 66.134 1.00 98.27 ? 365 PRO A CA 1 ATOM 2811 C C . PRO A 1 365 ? -12.264 90.297 65.523 1.00 90.82 ? 365 PRO A C 1 ATOM 2812 O O . PRO A 1 365 ? -12.476 90.412 64.315 1.00 86.29 ? 365 PRO A O 1 ATOM 2813 C CB . PRO A 1 365 ? -9.894 89.912 66.263 1.00 91.64 ? 365 PRO A CB 1 ATOM 2814 C CG . PRO A 1 365 ? -9.207 90.243 67.540 1.00 88.77 ? 365 PRO A CG 1 ATOM 2815 C CD . PRO A 1 365 ? -10.296 90.723 68.440 1.00 96.19 ? 365 PRO A CD 1 ATOM 2816 N N . ASP A 1 366 ? -13.070 89.632 66.352 1.00 82.49 ? 366 ASP A N 1 ATOM 2817 C CA . ASP A 1 366 ? -14.247 88.882 65.893 1.00 82.81 ? 366 ASP A CA 1 ATOM 2818 C C . ASP A 1 366 ? -15.327 89.778 65.282 1.00 89.86 ? 366 ASP A C 1 ATOM 2819 O O . ASP A 1 366 ? -16.259 90.208 65.966 1.00 97.36 ? 366 ASP A O 1 ATOM 2820 C CB . ASP A 1 366 ? -14.831 88.044 67.037 1.00 85.09 ? 366 ASP A CB 1 ATOM 2821 C CG . ASP A 1 366 ? -13.819 87.084 67.638 1.00 85.81 ? 366 ASP A CG 1 ATOM 2822 O OD1 . ASP A 1 366 ? -12.743 87.542 68.081 1.00 86.36 ? 366 ASP A OD1 1 ATOM 2823 O OD2 . ASP A 1 366 ? -14.107 85.870 67.678 1.00 83.64 ? 366 ASP A OD2 1 ATOM 2824 N N . ARG A 1 367 ? -15.193 90.037 63.983 1.00 87.65 ? 367 ARG A N 1 ATOM 2825 C CA . ARG A 1 367 ? -16.077 90.951 63.255 1.00 89.97 ? 367 ARG A CA 1 ATOM 2826 C C . ARG A 1 367 ? -17.455 90.360 62.943 1.00 98.96 ? 367 ARG A C 1 ATOM 2827 O O . ARG A 1 367 ? -18.383 91.097 62.595 1.00 97.24 ? 367 ARG A O 1 ATOM 2828 C CB . ARG A 1 367 ? -15.408 91.414 61.954 1.00 91.29 ? 367 ARG A CB 1 ATOM 2829 C CG . ARG A 1 367 ? -14.183 92.306 62.142 1.00 92.49 ? 367 ARG A CG 1 ATOM 2830 C CD . ARG A 1 367 ? -13.386 92.464 60.849 1.00 97.93 ? 367 ARG A CD 1 ATOM 2831 N NE . ARG A 1 367 ? -14.058 93.321 59.870 1.00 111.80 ? 367 ARG A NE 1 ATOM 2832 C CZ . ARG A 1 367 ? -14.736 92.882 58.811 1.00 108.10 ? 367 ARG A CZ 1 ATOM 2833 N NH1 . ARG A 1 367 ? -14.848 91.582 58.568 1.00 102.92 ? 367 ARG A NH1 1 ATOM 2834 N NH2 . ARG A 1 367 ? -15.307 93.751 57.988 1.00 100.45 ? 367 ARG A NH2 1 ATOM 2835 N N . TYR A 1 368 ? -17.584 89.040 63.064 1.00 106.74 ? 368 TYR A N 1 ATOM 2836 C CA . TYR A 1 368 ? -18.822 88.341 62.694 1.00 113.68 ? 368 TYR A CA 1 ATOM 2837 C C . TYR A 1 368 ? -19.619 87.829 63.896 1.00 107.69 ? 368 TYR A C 1 ATOM 2838 O O . TYR A 1 368 ? -20.808 87.519 63.774 1.00 100.71 ? 368 TYR A O 1 ATOM 2839 C CB . TYR A 1 368 ? -18.536 87.219 61.683 1.00 108.07 ? 368 TYR A CB 1 ATOM 2840 C CG . TYR A 1 368 ? -18.020 87.738 60.356 1.00 101.07 ? 368 TYR A CG 1 ATOM 2841 C CD1 . TYR A 1 368 ? -18.902 88.154 59.356 1.00 101.39 ? 368 TYR A CD1 1 ATOM 2842 C CD2 . TYR A 1 368 ? -16.649 87.833 60.108 1.00 97.34 ? 368 TYR A CD2 1 ATOM 2843 C CE1 . TYR A 1 368 ? -18.431 88.644 58.141 1.00 107.94 ? 368 TYR A CE1 1 ATOM 2844 C CE2 . TYR A 1 368 ? -16.168 88.322 58.896 1.00 96.78 ? 368 TYR A CE2 1 ATOM 2845 C CZ . TYR A 1 368 ? -17.064 88.725 57.920 1.00 104.99 ? 368 TYR A CZ 1 ATOM 2846 O OH . TYR A 1 368 ? -16.591 89.207 56.721 1.00 105.43 ? 368 TYR A OH 1 ATOM 2847 N N . MET A 1 369 ? -18.963 87.742 65.050 1.00 107.26 ? 369 MET A N 1 ATOM 2848 C CA . MET A 1 369 ? -19.656 87.484 66.309 1.00 122.97 ? 369 MET A CA 1 ATOM 2849 C C . MET A 1 369 ? -19.527 88.678 67.253 1.00 138.88 ? 369 MET A C 1 ATOM 2850 O O . MET A 1 369 ? -18.512 88.835 67.940 1.00 142.97 ? 369 MET A O 1 ATOM 2851 C CB . MET A 1 369 ? -19.157 86.197 66.972 1.00 117.07 ? 369 MET A CB 1 ATOM 2852 C CG . MET A 1 369 ? -20.030 84.985 66.690 1.00 131.06 ? 369 MET A CG 1 ATOM 2853 S SD . MET A 1 369 ? -19.865 83.699 67.946 1.00 156.60 ? 369 MET A SD 1 ATOM 2854 C CE . MET A 1 369 ? -21.236 82.622 67.526 1.00 147.45 ? 369 MET A CE 1 ATOM 2855 N N . GLN A 1 370 ? -20.559 89.522 67.264 1.00 141.97 ? 370 GLN A N 1 ATOM 2856 C CA . GLN A 1 370 ? -20.594 90.718 68.110 1.00 140.43 ? 370 GLN A CA 1 ATOM 2857 C C . GLN A 1 370 ? -20.892 90.348 69.562 1.00 143.88 ? 370 GLN A C 1 ATOM 2858 O O . GLN A 1 370 ? -21.784 89.538 69.837 1.00 139.27 ? 370 GLN A O 1 ATOM 2859 C CB . GLN A 1 370 ? -21.608 91.736 67.577 1.00 142.09 ? 370 GLN A CB 1 ATOM 2860 C CG . GLN A 1 370 ? -21.156 92.450 66.301 1.00 140.49 ? 370 GLN A CG 1 ATOM 2861 C CD . GLN A 1 370 ? -22.236 93.326 65.686 1.00 143.39 ? 370 GLN A CD 1 ATOM 2862 O OE1 . GLN A 1 370 ? -22.031 94.521 65.469 1.00 138.04 ? 370 GLN A OE1 1 ATOM 2863 N NE2 . GLN A 1 370 ? -23.392 92.734 65.399 1.00 143.41 ? 370 GLN A NE2 1 ATOM 2864 N N . GLN A 1 371 ? -20.135 90.946 70.480 1.00 139.22 ? 371 GLN A N 1 ATOM 2865 C CA . GLN A 1 371 ? -20.122 90.521 71.880 1.00 139.05 ? 371 GLN A CA 1 ATOM 2866 C C . GLN A 1 371 ? -20.204 91.675 72.882 1.00 142.24 ? 371 GLN A C 1 ATOM 2867 O O . GLN A 1 371 ? -20.071 92.849 72.517 1.00 131.95 ? 371 GLN A O 1 ATOM 2868 C CB . GLN A 1 371 ? -18.866 89.684 72.158 1.00 132.33 ? 371 GLN A CB 1 ATOM 2869 C CG . GLN A 1 371 ? -18.889 88.275 71.571 1.00 130.91 ? 371 GLN A CG 1 ATOM 2870 C CD . GLN A 1 371 ? -17.540 87.576 71.651 1.00 121.49 ? 371 GLN A CD 1 ATOM 2871 O OE1 . GLN A 1 371 ? -16.489 88.201 71.499 1.00 105.07 ? 371 GLN A OE1 1 ATOM 2872 N NE2 . GLN A 1 371 ? -17.568 86.269 71.882 1.00 120.33 ? 371 GLN A NE2 1 ATOM 2873 N N . ASN A 1 372 ? -20.431 91.317 74.147 1.00 144.42 ? 372 ASN A N 1 ATOM 2874 C CA . ASN A 1 372 ? -20.394 92.258 75.264 1.00 139.76 ? 372 ASN A CA 1 ATOM 2875 C C . ASN A 1 372 ? -18.975 92.499 75.759 1.00 130.02 ? 372 ASN A C 1 ATOM 2876 O O . ASN A 1 372 ? -18.256 91.557 76.107 1.00 123.32 ? 372 ASN A O 1 ATOM 2877 C CB . ASN A 1 372 ? -21.268 91.764 76.426 1.00 144.01 ? 372 ASN A CB 1 ATOM 2878 C CG . ASN A 1 372 ? -22.591 92.511 76.534 1.00 152.05 ? 372 ASN A CG 1 ATOM 2879 O OD1 . ASN A 1 372 ? -23.075 93.102 75.565 1.00 157.95 ? 372 ASN A OD1 1 ATOM 2880 N ND2 . ASN A 1 372 ? -23.184 92.486 77.724 1.00 142.36 ? 372 ASN A ND2 1 ATOM 2881 N N . ILE A 1 373 ? -18.581 93.768 75.783 1.00 129.50 ? 373 ILE A N 1 ATOM 2882 C CA . ILE A 1 373 ? -17.291 94.172 76.327 1.00 123.09 ? 373 ILE A CA 1 ATOM 2883 C C . ILE A 1 373 ? -17.461 94.442 77.825 1.00 118.16 ? 373 ILE A C 1 ATOM 2884 O O . ILE A 1 373 ? -18.262 95.290 78.227 1.00 111.74 ? 373 ILE A O 1 ATOM 2885 C CB . ILE A 1 373 ? -16.721 95.417 75.602 1.00 121.13 ? 373 ILE A CB 1 ATOM 2886 C CG1 . ILE A 1 373 ? -17.091 95.398 74.111 1.00 119.02 ? 373 ILE A CG1 1 ATOM 2887 C CG2 . ILE A 1 373 ? -15.207 95.494 75.793 1.00 113.91 ? 373 ILE A CG2 1 ATOM 2888 C CD1 . ILE A 1 373 ? -17.164 96.773 73.459 1.00 115.76 ? 373 ILE A CD1 1 ATOM 2889 N N . ARG A 1 374 ? -16.712 93.703 78.640 1.00 113.74 ? 374 ARG A N 1 ATOM 2890 C CA . ARG A 1 374 ? -16.846 93.748 80.096 1.00 113.67 ? 374 ARG A CA 1 ATOM 2891 C C . ARG A 1 374 ? -15.665 94.482 80.745 1.00 116.75 ? 374 ARG A C 1 ATOM 2892 O O . ARG A 1 374 ? -14.625 93.875 81.016 1.00 117.79 ? 374 ARG A O 1 ATOM 2893 C CB . ARG A 1 374 ? -16.960 92.319 80.648 1.00 112.78 ? 374 ARG A CB 1 ATOM 2894 C CG . ARG A 1 374 ? -17.258 92.205 82.142 1.00 110.69 ? 374 ARG A CG 1 ATOM 2895 C CD . ARG A 1 374 ? -18.679 91.729 82.406 1.00 123.73 ? 374 ARG A CD 1 ATOM 2896 N NE . ARG A 1 374 ? -19.672 92.791 82.248 1.00 130.90 ? 374 ARG A NE 1 ATOM 2897 C CZ . ARG A 1 374 ? -20.976 92.641 82.469 1.00 128.91 ? 374 ARG A CZ 1 ATOM 2898 N NH1 . ARG A 1 374 ? -21.463 91.469 82.858 1.00 118.68 ? 374 ARG A NH1 1 ATOM 2899 N NH2 . ARG A 1 374 ? -21.796 93.669 82.300 1.00 123.87 ? 374 ARG A NH2 1 ATOM 2900 N N . TYR A 1 375 ? -15.826 95.782 80.990 1.00 112.21 ? 375 TYR A N 1 ATOM 2901 C CA . TYR A 1 375 ? -14.804 96.568 81.688 1.00 104.58 ? 375 TYR A CA 1 ATOM 2902 C C . TYR A 1 375 ? -14.976 96.445 83.202 1.00 108.55 ? 375 TYR A C 1 ATOM 2903 O O . TYR A 1 375 ? -16.017 96.824 83.747 1.00 112.62 ? 375 TYR A O 1 ATOM 2904 C CB . TYR A 1 375 ? -14.864 98.042 81.276 1.00 103.79 ? 375 TYR A CB 1 ATOM 2905 C CG . TYR A 1 375 ? -14.668 98.306 79.798 1.00 106.35 ? 375 TYR A CG 1 ATOM 2906 C CD1 . TYR A 1 375 ? -15.764 98.490 78.955 1.00 112.50 ? 375 TYR A CD1 1 ATOM 2907 C CD2 . TYR A 1 375 ? -13.389 98.394 79.245 1.00 102.67 ? 375 TYR A CD2 1 ATOM 2908 C CE1 . TYR A 1 375 ? -15.596 98.745 77.597 1.00 111.74 ? 375 TYR A CE1 1 ATOM 2909 C CE2 . TYR A 1 375 ? -13.209 98.649 77.885 1.00 107.52 ? 375 TYR A CE2 1 ATOM 2910 C CZ . TYR A 1 375 ? -14.319 98.823 77.068 1.00 110.37 ? 375 TYR A CZ 1 ATOM 2911 O OH . TYR A 1 375 ? -14.158 99.075 75.724 1.00 104.04 ? 375 TYR A OH 1 ATOM 2912 N N . THR A 1 376 ? -13.955 95.912 83.876 1.00 104.75 ? 376 THR A N 1 ATOM 2913 C CA . THR A 1 376 ? -14.007 95.696 85.328 1.00 104.24 ? 376 THR A CA 1 ATOM 2914 C C . THR A 1 376 ? -12.722 96.101 86.055 1.00 105.48 ? 376 THR A C 1 ATOM 2915 O O . THR A 1 376 ? -11.652 96.203 85.449 1.00 105.14 ? 376 THR A O 1 ATOM 2916 C CB . THR A 1 376 ? -14.325 94.221 85.688 1.00 95.76 ? 376 THR A CB 1 ATOM 2917 O OG1 . THR A 1 376 ? -13.445 93.348 84.969 1.00 98.50 ? 376 THR A OG1 1 ATOM 2918 C CG2 . THR A 1 376 ? -15.778 93.871 85.366 1.00 98.17 ? 376 THR A CG2 1 ATOM 2919 N N . LYS A 1 377 ? -12.856 96.324 87.362 1.00 104.52 ? 377 LYS A N 1 ATOM 2920 C CA . LYS A 1 377 ? -11.748 96.645 88.260 1.00 102.13 ? 377 LYS A CA 1 ATOM 2921 C C . LYS A 1 377 ? -10.717 95.514 88.284 1.00 98.93 ? 377 LYS A C 1 ATOM 2922 O O . LYS A 1 377 ? -11.078 94.338 88.202 1.00 95.54 ? 377 LYS A O 1 ATOM 2923 C CB . LYS A 1 377 ? -12.298 96.854 89.675 1.00 109.79 ? 377 LYS A CB 1 ATOM 2924 C CG . LYS A 1 377 ? -11.412 97.654 90.621 1.00 104.93 ? 377 LYS A CG 1 ATOM 2925 C CD . LYS A 1 377 ? -11.992 99.033 90.892 1.00 95.87 ? 377 LYS A CD 1 ATOM 2926 C CE . LYS A 1 377 ? -11.394 99.624 92.155 1.00 96.46 ? 377 LYS A CE 1 ATOM 2927 N NZ . LYS A 1 377 ? -12.160 100.792 92.655 1.00 93.17 ? 377 LYS A NZ 1 ATOM 2928 N N . LEU A 1 378 ? -9.440 95.872 88.396 1.00 98.72 ? 378 LEU A N 1 ATOM 2929 C CA . LEU A 1 378 ? -8.385 94.874 88.556 1.00 100.65 ? 378 LEU A CA 1 ATOM 2930 C C . LEU A 1 378 ? -7.495 95.169 89.767 1.00 104.35 ? 378 LEU A C 1 ATOM 2931 O O . LEU A 1 378 ? -7.723 94.621 90.848 1.00 102.85 ? 378 LEU A O 1 ATOM 2932 C CB . LEU A 1 378 ? -7.552 94.734 87.275 1.00 98.72 ? 378 LEU A CB 1 ATOM 2933 C CG . LEU A 1 378 ? -6.900 93.380 86.957 1.00 98.97 ? 378 LEU A CG 1 ATOM 2934 C CD1 . LEU A 1 378 ? -6.339 93.405 85.551 1.00 98.07 ? 378 LEU A CD1 1 ATOM 2935 C CD2 . LEU A 1 378 ? -5.810 92.974 87.950 1.00 100.88 ? 378 LEU A CD2 1 ATOM 2936 N N . SER A 1 379 ? -6.491 96.028 89.589 1.00 103.31 ? 379 SER A N 1 ATOM 2937 C CA . SER A 1 379 ? -5.523 96.306 90.654 1.00 104.00 ? 379 SER A CA 1 ATOM 2938 C C . SER A 1 379 ? -5.101 97.771 90.756 1.00 103.34 ? 379 SER A C 1 ATOM 2939 O O . SER A 1 379 ? -4.218 98.230 90.024 1.00 95.97 ? 379 SER A O 1 ATOM 2940 C CB . SER A 1 379 ? -4.288 95.406 90.511 1.00 100.24 ? 379 SER A CB 1 ATOM 2941 O OG . SER A 1 379 ? -3.317 95.704 91.499 1.00 86.46 ? 379 SER A OG 1 ATOM 2942 N N . ASP A 1 380 ? -5.749 98.494 91.669 1.00 109.61 ? 380 ASP A N 1 ATOM 2943 C CA . ASP A 1 380 ? -5.309 99.833 92.071 1.00 105.83 ? 380 ASP A CA 1 ATOM 2944 C C . ASP A 1 380 ? -5.198 99.927 93.601 1.00 101.01 ? 380 ASP A C 1 ATOM 2945 O O . ASP A 1 380 ? -6.212 99.963 94.301 1.00 103.10 ? 380 ASP A O 1 ATOM 2946 C CB . ASP A 1 380 ? -6.194 100.945 91.464 1.00 102.00 ? 380 ASP A CB 1 ATOM 2947 C CG . ASP A 1 380 ? -7.632 100.935 91.982 1.00 98.70 ? 380 ASP A CG 1 ATOM 2948 O OD1 . ASP A 1 380 ? -8.237 102.027 92.037 1.00 86.78 ? 380 ASP A OD1 1 ATOM 2949 O OD2 . ASP A 1 380 ? -8.162 99.855 92.322 1.00 98.52 ? 380 ASP A OD2 1 ATOM 2950 N N . PRO A 1 381 ? -3.954 99.944 94.123 1.00 97.92 ? 381 PRO A N 1 ATOM 2951 C CA . PRO A 1 381 ? -3.695 99.896 95.568 1.00 102.35 ? 381 PRO A CA 1 ATOM 2952 C C . PRO A 1 381 ? -4.254 101.083 96.365 1.00 104.97 ? 381 PRO A C 1 ATOM 2953 O O . PRO A 1 381 ? -4.025 101.173 97.574 1.00 102.96 ? 381 PRO A O 1 ATOM 2954 C CB . PRO A 1 381 ? -2.160 99.870 95.650 1.00 98.04 ? 381 PRO A CB 1 ATOM 2955 C CG . PRO A 1 381 ? -1.703 99.424 94.305 1.00 82.70 ? 381 PRO A CG 1 ATOM 2956 C CD . PRO A 1 381 ? -2.698 99.998 93.354 1.00 89.37 ? 381 PRO A CD 1 ATOM 2957 N N . ALA A 1 382 ? -4.991 101.968 95.695 1.00 105.49 ? 382 ALA A N 1 ATOM 2958 C CA . ALA A 1 382 ? -5.519 103.180 96.323 1.00 105.78 ? 382 ALA A CA 1 ATOM 2959 C C . ALA A 1 382 ? -7.046 103.288 96.299 1.00 100.70 ? 382 ALA A C 1 ATOM 2960 O O . ALA A 1 382 ? -7.628 103.996 97.125 1.00 103.98 ? 382 ALA A O 1 ATOM 2961 C CB . ALA A 1 382 ? -4.895 104.411 95.688 1.00 106.67 ? 382 ALA A CB 1 ATOM 2962 N N . ASN A 1 383 ? -7.682 102.591 95.357 1.00 101.08 ? 383 ASN A N 1 ATOM 2963 C CA . ASN A 1 383 ? -9.139 102.642 95.165 1.00 102.43 ? 383 ASN A CA 1 ATOM 2964 C C . ASN A 1 383 ? -9.673 104.041 94.834 1.00 103.83 ? 383 ASN A C 1 ATOM 2965 O O . ASN A 1 383 ? -10.737 104.441 95.316 1.00 102.99 ? 383 ASN A O 1 ATOM 2966 C CB . ASN A 1 383 ? -9.885 102.034 96.366 1.00 98.91 ? 383 ASN A CB 1 ATOM 2967 C CG . ASN A 1 383 ? -9.815 100.518 96.396 1.00 112.88 ? 383 ASN A CG 1 ATOM 2968 O OD1 . ASN A 1 383 ? -9.205 99.932 97.291 1.00 114.87 ? 383 ASN A OD1 1 ATOM 2969 N ND2 . ASN A 1 383 ? -10.442 99.874 95.416 1.00 111.41 ? 383 ASN A ND2 1 ATOM 2970 N N . TRP A 1 384 ? -8.929 104.775 94.007 1.00 102.37 ? 384 TRP A N 1 ATOM 2971 C CA . TRP A 1 384 ? -9.350 106.103 93.555 1.00 102.86 ? 384 TRP A CA 1 ATOM 2972 C C . TRP A 1 384 ? -10.139 106.038 92.247 1.00 104.82 ? 384 TRP A C 1 ATOM 2973 O O . TRP A 1 384 ? -10.613 107.064 91.752 1.00 101.87 ? 384 TRP A O 1 ATOM 2974 C CB . TRP A 1 384 ? -8.143 107.032 93.356 1.00 104.11 ? 384 TRP A CB 1 ATOM 2975 C CG . TRP A 1 384 ? -7.261 107.244 94.561 1.00 112.69 ? 384 TRP A CG 1 ATOM 2976 C CD1 . TRP A 1 384 ? -7.569 106.987 95.870 1.00 117.63 ? 384 TRP A CD1 1 ATOM 2977 C CD2 . TRP A 1 384 ? -5.938 107.800 94.564 1.00 106.99 ? 384 TRP A CD2 1 ATOM 2978 N NE1 . TRP A 1 384 ? -6.512 107.327 96.682 1.00 115.80 ? 384 TRP A NE1 1 ATOM 2979 C CE2 . TRP A 1 384 ? -5.500 107.832 95.908 1.00 110.53 ? 384 TRP A CE2 1 ATOM 2980 C CE3 . TRP A 1 384 ? -5.078 108.269 93.561 1.00 94.34 ? 384 TRP A CE3 1 ATOM 2981 C CZ2 . TRP A 1 384 ? -4.236 108.310 96.275 1.00 105.22 ? 384 TRP A CZ2 1 ATOM 2982 C CZ3 . TRP A 1 384 ? -3.822 108.746 93.927 1.00 94.06 ? 384 TRP A CZ3 1 ATOM 2983 C CH2 . TRP A 1 384 ? -3.415 108.761 95.273 1.00 100.90 ? 384 TRP A CH2 1 ATOM 2984 N N . LEU A 1 385 ? -10.281 104.833 91.697 1.00 111.41 ? 385 LEU A N 1 ATOM 2985 C CA . LEU A 1 385 ? -10.784 104.659 90.332 1.00 107.07 ? 385 LEU A CA 1 ATOM 2986 C C . LEU A 1 385 ? -12.024 103.773 90.221 1.00 105.89 ? 385 LEU A C 1 ATOM 2987 O O . LEU A 1 385 ? -12.092 102.696 90.820 1.00 92.76 ? 385 LEU A O 1 ATOM 2988 C CB . LEU A 1 385 ? -9.668 104.118 89.434 1.00 101.11 ? 385 LEU A CB 1 ATOM 2989 C CG . LEU A 1 385 ? -8.394 104.967 89.349 1.00 96.04 ? 385 LEU A CG 1 ATOM 2990 C CD1 . LEU A 1 385 ? -7.172 104.090 89.150 1.00 95.73 ? 385 LEU A CD1 1 ATOM 2991 C CD2 . LEU A 1 385 ? -8.499 106.029 88.257 1.00 80.79 ? 385 LEU A CD2 1 ATOM 2992 N N . LYS A 1 386 ? -12.994 104.241 89.438 1.00 111.63 ? 386 LYS A N 1 ATOM 2993 C CA . LYS A 1 386 ? -14.226 103.504 89.162 1.00 114.52 ? 386 LYS A CA 1 ATOM 2994 C C . LYS A 1 386 ? -14.435 103.391 87.652 1.00 116.61 ? 386 LYS A C 1 ATOM 2995 O O . LYS A 1 386 ? -14.080 104.302 86.900 1.00 117.14 ? 386 LYS A O 1 ATOM 2996 C CB . LYS A 1 386 ? -15.424 104.208 89.808 1.00 113.35 ? 386 LYS A CB 1 ATOM 2997 C CG . LYS A 1 386 ? -16.687 103.360 89.917 1.00 117.87 ? 386 LYS A CG 1 ATOM 2998 C CD . LYS A 1 386 ? -17.859 104.179 90.441 1.00 121.06 ? 386 LYS A CD 1 ATOM 2999 C CE . LYS A 1 386 ? -19.116 103.332 90.576 1.00 125.51 ? 386 LYS A CE 1 ATOM 3000 N NZ . LYS A 1 386 ? -20.263 104.123 91.104 1.00 115.22 ? 386 LYS A NZ 1 ATOM 3001 N N . ILE A 1 387 ? -15.007 102.269 87.219 1.00 119.34 ? 387 ILE A N 1 ATOM 3002 C CA . ILE A 1 387 ? -15.313 102.033 85.804 1.00 116.56 ? 387 ILE A CA 1 ATOM 3003 C C . ILE A 1 387 ? -16.585 101.189 85.647 1.00 117.81 ? 387 ILE A C 1 ATOM 3004 O O . ILE A 1 387 ? -16.789 100.215 86.378 1.00 119.16 ? 387 ILE A O 1 ATOM 3005 C CB . ILE A 1 387 ? -14.098 101.407 85.041 1.00 115.53 ? 387 ILE A CB 1 ATOM 3006 C CG1 . ILE A 1 387 ? -14.362 101.354 83.529 1.00 119.00 ? 387 ILE A CG1 1 ATOM 3007 C CG2 . ILE A 1 387 ? -13.715 100.032 85.621 1.00 112.47 ? 387 ILE A CG2 1 ATOM 3008 C CD1 . ILE A 1 387 ? -13.111 101.177 82.680 1.00 113.78 ? 387 ILE A CD1 1 ATOM 3009 N N . ASP A 1 388 ? -17.440 101.578 84.703 1.00 112.85 ? 388 ASP A N 1 ATOM 3010 C CA . ASP A 1 388 ? -18.689 100.859 84.446 1.00 117.99 ? 388 ASP A CA 1 ATOM 3011 C C . ASP A 1 388 ? -18.603 99.984 83.184 1.00 120.50 ? 388 ASP A C 1 ATOM 3012 O O . ASP A 1 388 ? -17.919 100.352 82.224 1.00 118.66 ? 388 ASP A O 1 ATOM 3013 C CB . ASP A 1 388 ? -19.876 101.831 84.377 1.00 121.65 ? 388 ASP A CB 1 ATOM 3014 C CG . ASP A 1 388 ? -19.784 102.801 83.210 1.00 122.69 ? 388 ASP A CG 1 ATOM 3015 O OD1 . ASP A 1 388 ? -20.845 103.124 82.637 1.00 117.95 ? 388 ASP A OD1 1 ATOM 3016 O OD2 . ASP A 1 388 ? -18.664 103.242 82.868 1.00 119.83 ? 388 ASP A OD2 1 ATOM 3017 N N . PRO A 1 389 ? -19.288 98.818 83.193 1.00 124.08 ? 389 PRO A N 1 ATOM 3018 C CA . PRO A 1 389 ? -19.223 97.819 82.113 1.00 122.26 ? 389 PRO A CA 1 ATOM 3019 C C . PRO A 1 389 ? -19.641 98.313 80.721 1.00 113.45 ? 389 PRO A C 1 ATOM 3020 O O . PRO A 1 389 ? -18.920 98.078 79.752 1.00 116.63 ? 389 PRO A O 1 ATOM 3021 C CB . PRO A 1 389 ? -20.181 96.718 82.593 1.00 126.18 ? 389 PRO A CB 1 ATOM 3022 C CG . PRO A 1 389 ? -20.244 96.887 84.071 1.00 125.83 ? 389 PRO A CG 1 ATOM 3023 C CD . PRO A 1 389 ? -20.172 98.366 84.285 1.00 124.31 ? 389 PRO A CD 1 ATOM 3024 N N . VAL A 1 390 ? -20.788 98.984 80.630 1.00 115.12 ? 390 VAL A N 1 ATOM 3025 C CA . VAL A 1 390 ? -21.347 99.416 79.341 1.00 119.72 ? 390 VAL A CA 1 ATOM 3026 C C . VAL A 1 390 ? -20.486 100.485 78.650 1.00 119.11 ? 390 VAL A C 1 ATOM 3027 O O . VAL A 1 390 ? -20.206 100.383 77.453 1.00 109.77 ? 390 VAL A O 1 ATOM 3028 C CB . VAL A 1 390 ? -22.826 99.906 79.484 1.00 123.35 ? 390 VAL A CB 1 ATOM 3029 C CG1 . VAL A 1 390 ? -23.418 100.294 78.129 1.00 110.29 ? 390 VAL A CG1 1 ATOM 3030 C CG2 . VAL A 1 390 ? -23.691 98.838 80.146 1.00 123.57 ? 390 VAL A CG2 1 ATOM 3031 N N . ASN A 1 391 ? -20.058 101.490 79.412 1.00 128.09 ? 391 ASN A N 1 ATOM 3032 C CA . ASN A 1 391 ? -19.355 102.653 78.861 1.00 126.61 ? 391 ASN A CA 1 ATOM 3033 C C . ASN A 1 391 ? -17.837 102.503 78.755 1.00 117.02 ? 391 ASN A C 1 ATOM 3034 O O . ASN A 1 391 ? -17.253 102.803 77.713 1.00 106.34 ? 391 ASN A O 1 ATOM 3035 C CB . ASN A 1 391 ? -19.699 103.914 79.664 1.00 123.19 ? 391 ASN A CB 1 ATOM 3036 C CG . ASN A 1 391 ? -21.126 104.381 79.441 1.00 127.66 ? 391 ASN A CG 1 ATOM 3037 O OD1 . ASN A 1 391 ? -21.458 104.918 78.383 1.00 131.03 ? 391 ASN A OD1 1 ATOM 3038 N ND2 . ASN A 1 391 ? -21.976 104.191 80.445 1.00 119.83 ? 391 ASN A ND2 1 ATOM 3039 N N . GLY A 1 392 ? -17.207 102.050 79.836 1.00 117.16 ? 392 GLY A N 1 ATOM 3040 C CA . GLY A 1 392 ? -15.749 101.981 79.911 1.00 111.97 ? 392 GLY A CA 1 ATOM 3041 C C . GLY A 1 392 ? -15.113 103.297 80.327 1.00 122.13 ? 392 GLY A C 1 ATOM 3042 O O . GLY A 1 392 ? -13.887 103.427 80.332 1.00 118.58 ? 392 GLY A O 1 ATOM 3043 N N . GLN A 1 393 ? -15.954 104.273 80.671 1.00 125.91 ? 393 GLN A N 1 ATOM 3044 C CA . GLN A 1 393 ? -15.504 105.582 81.149 1.00 117.35 ? 393 GLN A CA 1 ATOM 3045 C C . GLN A 1 393 ? -14.919 105.453 82.550 1.00 116.37 ? 393 GLN A C 1 ATOM 3046 O O . GLN A 1 393 ? -15.375 104.625 83.344 1.00 115.56 ? 393 GLN A O 1 ATOM 3047 C CB . GLN A 1 393 ? -16.670 106.577 81.171 1.00 116.38 ? 393 GLN A CB 1 ATOM 3048 C CG . GLN A 1 393 ? -17.370 106.773 79.828 1.00 120.82 ? 393 GLN A CG 1 ATOM 3049 C CD . GLN A 1 393 ? -18.472 107.819 79.877 1.00 116.24 ? 393 GLN A CD 1 ATOM 3050 O OE1 . GLN A 1 393 ? -19.424 107.704 80.650 1.00 113.15 ? 393 GLN A OE1 1 ATOM 3051 N NE2 . GLN A 1 393 ? -18.351 108.841 79.038 1.00 114.88 ? 393 GLN A NE2 1 ATOM 3052 N N . ILE A 1 394 ? -13.911 106.270 82.852 1.00 117.88 ? 394 ILE A N 1 ATOM 3053 C CA . ILE A 1 394 ? -13.290 106.262 84.178 1.00 117.50 ? 394 ILE A CA 1 ATOM 3054 C C . ILE A 1 394 ? -13.565 107.558 84.943 1.00 118.56 ? 394 ILE A C 1 ATOM 3055 O O . ILE A 1 394 ? -13.274 108.656 84.457 1.00 114.38 ? 394 ILE A O 1 ATOM 3056 C CB . ILE A 1 394 ? -11.765 105.999 84.116 1.00 109.90 ? 394 ILE A CB 1 ATOM 3057 C CG1 . ILE A 1 394 ? -11.451 104.839 83.168 1.00 104.89 ? 394 ILE A CG1 1 ATOM 3058 C CG2 . ILE A 1 394 ? -11.215 105.711 85.515 1.00 112.51 ? 394 ILE A CG2 1 ATOM 3059 C CD1 . ILE A 1 394 ? -9.993 104.734 82.793 1.00 108.32 ? 394 ILE A CD1 1 ATOM 3060 N N . THR A 1 395 ? -14.134 107.411 86.138 1.00 115.73 ? 395 THR A N 1 ATOM 3061 C CA . THR A 1 395 ? -14.410 108.535 87.032 1.00 111.61 ? 395 THR A CA 1 ATOM 3062 C C . THR A 1 395 ? -13.730 108.318 88.385 1.00 112.16 ? 395 THR A C 1 ATOM 3063 O O . THR A 1 395 ? -13.548 107.177 88.821 1.00 106.89 ? 395 THR A O 1 ATOM 3064 C CB . THR A 1 395 ? -15.928 108.748 87.241 1.00 114.53 ? 395 THR A CB 1 ATOM 3065 O OG1 . THR A 1 395 ? -16.541 107.512 87.629 1.00 117.37 ? 395 THR A OG1 1 ATOM 3066 C CG2 . THR A 1 395 ? -16.591 109.262 85.965 1.00 107.66 ? 395 THR A CG2 1 ATOM 3067 N N . THR A 1 396 ? -13.361 109.417 89.040 1.00 112.23 ? 396 THR A N 1 ATOM 3068 C CA . THR A 1 396 ? -12.636 109.370 90.314 1.00 107.77 ? 396 THR A CA 1 ATOM 3069 C C . THR A 1 396 ? -13.530 109.034 91.508 1.00 104.78 ? 396 THR A C 1 ATOM 3070 O O . THR A 1 396 ? -14.665 109.506 91.603 1.00 103.79 ? 396 THR A O 1 ATOM 3071 C CB . THR A 1 396 ? -11.888 110.696 90.599 1.00 109.55 ? 396 THR A CB 1 ATOM 3072 O OG1 . THR A 1 396 ? -12.765 111.807 90.374 1.00 113.30 ? 396 THR A OG1 1 ATOM 3073 C CG2 . THR A 1 396 ? -10.670 110.830 89.702 1.00 103.34 ? 396 THR A CG2 1 ATOM 3074 N N . ILE A 1 397 ? -13.000 108.213 92.412 1.00 102.28 ? 397 ILE A N 1 ATOM 3075 C CA . ILE A 1 397 ? -13.678 107.864 93.661 1.00 105.87 ? 397 ILE A CA 1 ATOM 3076 C C . ILE A 1 397 ? -13.230 108.786 94.800 1.00 111.50 ? 397 ILE A C 1 ATOM 3077 O O . ILE A 1 397 ? -14.053 109.244 95.597 1.00 110.80 ? 397 ILE A O 1 ATOM 3078 C CB . ILE A 1 397 ? -13.456 106.362 94.029 1.00 101.62 ? 397 ILE A CB 1 ATOM 3079 C CG1 . ILE A 1 397 ? -14.334 105.452 93.157 1.00 102.40 ? 397 ILE A CG1 1 ATOM 3080 C CG2 . ILE A 1 397 ? -13.696 106.091 95.523 1.00 104.41 ? 397 ILE A CG2 1 ATOM 3081 C CD1 . ILE A 1 397 ? -15.848 105.643 93.324 1.00 100.70 ? 397 ILE A CD1 1 ATOM 3082 N N . ALA A 1 398 ? -11.928 109.060 94.860 1.00 111.46 ? 398 ALA A N 1 ATOM 3083 C CA . ALA A 1 398 ? -11.353 109.907 95.904 1.00 111.21 ? 398 ALA A CA 1 ATOM 3084 C C . ALA A 1 398 ? -10.474 111.025 95.332 1.00 110.54 ? 398 ALA A C 1 ATOM 3085 O O . ALA A 1 398 ? -10.298 111.135 94.113 1.00 104.28 ? 398 ALA A O 1 ATOM 3086 C CB . ALA A 1 398 ? -10.566 109.054 96.901 1.00 105.81 ? 398 ALA A CB 1 ATOM 3087 N N . VAL A 1 399 ? -9.940 111.860 96.222 1.00 118.10 ? 399 VAL A N 1 ATOM 3088 C CA . VAL A 1 399 ? -8.982 112.899 95.843 1.00 113.01 ? 399 VAL A CA 1 ATOM 3089 C C . VAL A 1 399 ? -7.612 112.283 95.559 1.00 103.87 ? 399 VAL A C 1 ATOM 3090 O O . VAL A 1 399 ? -7.143 111.412 96.298 1.00 100.30 ? 399 VAL A O 1 ATOM 3091 C CB . VAL A 1 399 ? -8.873 114.032 96.905 1.00 114.91 ? 399 VAL A CB 1 ATOM 3092 C CG1 . VAL A 1 399 ? -10.057 114.987 96.792 1.00 109.38 ? 399 VAL A CG1 1 ATOM 3093 C CG2 . VAL A 1 399 ? -8.750 113.467 98.328 1.00 116.51 ? 399 VAL A CG2 1 ATOM 3094 N N . LEU A 1 400 ? -6.982 112.743 94.483 1.00 92.45 ? 400 LEU A N 1 ATOM 3095 C CA . LEU A 1 400 ? -5.759 112.130 93.972 1.00 93.11 ? 400 LEU A CA 1 ATOM 3096 C C . LEU A 1 400 ? -4.510 112.819 94.524 1.00 91.22 ? 400 LEU A C 1 ATOM 3097 O O . LEU A 1 400 ? -4.090 113.861 94.020 1.00 87.67 ? 400 LEU A O 1 ATOM 3098 C CB . LEU A 1 400 ? -5.759 112.137 92.436 1.00 101.66 ? 400 LEU A CB 1 ATOM 3099 C CG . LEU A 1 400 ? -6.983 111.590 91.682 1.00 107.43 ? 400 LEU A CG 1 ATOM 3100 C CD1 . LEU A 1 400 ? -8.117 112.615 91.617 1.00 106.05 ? 400 LEU A CD1 1 ATOM 3101 C CD2 . LEU A 1 400 ? -6.591 111.157 90.278 1.00 89.67 ? 400 LEU A CD2 1 ATOM 3102 N N . ASP A 1 401 ? -3.926 112.222 95.563 1.00 94.56 ? 401 ASP A N 1 ATOM 3103 C CA . ASP A 1 401 ? -2.768 112.785 96.260 1.00 93.89 ? 401 ASP A CA 1 ATOM 3104 C C . ASP A 1 401 ? -1.460 112.162 95.765 1.00 88.20 ? 401 ASP A C 1 ATOM 3105 O O . ASP A 1 401 ? -1.205 110.978 95.993 1.00 91.01 ? 401 ASP A O 1 ATOM 3106 C CB . ASP A 1 401 ? -2.922 112.580 97.774 1.00 92.99 ? 401 ASP A CB 1 ATOM 3107 C CG . ASP A 1 401 ? -1.807 113.231 98.576 1.00 90.08 ? 401 ASP A CG 1 ATOM 3108 O OD1 . ASP A 1 401 ? -1.750 114.478 98.621 1.00 82.43 ? 401 ASP A OD1 1 ATOM 3109 O OD2 . ASP A 1 401 ? -0.996 112.494 99.176 1.00 91.91 ? 401 ASP A OD2 1 ATOM 3110 N N . ARG A 1 402 ? -0.633 112.964 95.097 1.00 76.81 ? 402 ARG A N 1 ATOM 3111 C CA . ARG A 1 402 ? 0.610 112.460 94.505 1.00 79.55 ? 402 ARG A CA 1 ATOM 3112 C C . ARG A 1 402 ? 1.738 112.242 95.523 1.00 80.41 ? 402 ARG A C 1 ATOM 3113 O O . ARG A 1 402 ? 2.645 111.442 95.283 1.00 82.97 ? 402 ARG A O 1 ATOM 3114 C CB . ARG A 1 402 ? 1.056 113.332 93.316 1.00 70.19 ? 402 ARG A CB 1 ATOM 3115 C CG . ARG A 1 402 ? 1.955 114.516 93.642 1.00 70.54 ? 402 ARG A CG 1 ATOM 3116 C CD . ARG A 1 402 ? 3.389 114.253 93.220 1.00 68.63 ? 402 ARG A CD 1 ATOM 3117 N NE . ARG A 1 402 ? 4.289 115.307 93.679 1.00 79.55 ? 402 ARG A NE 1 ATOM 3118 C CZ . ARG A 1 402 ? 5.043 115.233 94.773 1.00 87.77 ? 402 ARG A CZ 1 ATOM 3119 N NH1 . ARG A 1 402 ? 5.024 114.147 95.537 1.00 78.68 ? 402 ARG A NH1 1 ATOM 3120 N NH2 . ARG A 1 402 ? 5.825 116.251 95.105 1.00 89.35 ? 402 ARG A NH2 1 ATOM 3121 N N . GLU A 1 403 ? 1.679 112.947 96.652 1.00 82.19 ? 403 GLU A N 1 ATOM 3122 C CA . GLU A 1 403 ? 2.640 112.741 97.741 1.00 88.36 ? 403 GLU A CA 1 ATOM 3123 C C . GLU A 1 403 ? 2.174 111.625 98.673 1.00 93.69 ? 403 GLU A C 1 ATOM 3124 O O . GLU A 1 403 ? 1.913 111.845 99.860 1.00 94.89 ? 403 GLU A O 1 ATOM 3125 C CB . GLU A 1 403 ? 2.928 114.035 98.519 1.00 81.68 ? 403 GLU A CB 1 ATOM 3126 C CG . GLU A 1 403 ? 1.763 115.010 98.633 1.00 78.70 ? 403 GLU A CG 1 ATOM 3127 C CD . GLU A 1 403 ? 1.797 116.096 97.570 1.00 76.31 ? 403 GLU A CD 1 ATOM 3128 O OE1 . GLU A 1 403 ? 0.792 116.821 97.429 1.00 71.33 ? 403 GLU A OE1 1 ATOM 3129 O OE2 . GLU A 1 403 ? 2.825 116.238 96.875 1.00 75.62 ? 403 GLU A OE2 1 ATOM 3130 N N . SER A 1 404 ? 2.083 110.423 98.111 1.00 91.85 ? 404 SER A N 1 ATOM 3131 C CA . SER A 1 404 ? 1.595 109.253 98.823 1.00 98.21 ? 404 SER A CA 1 ATOM 3132 C C . SER A 1 404 ? 2.535 108.066 98.613 1.00 102.85 ? 404 SER A C 1 ATOM 3133 O O . SER A 1 404 ? 3.100 107.913 97.527 1.00 100.11 ? 404 SER A O 1 ATOM 3134 C CB . SER A 1 404 ? 0.185 108.900 98.338 1.00 93.30 ? 404 SER A CB 1 ATOM 3135 O OG . SER A 1 404 ? -0.357 107.804 99.055 1.00 91.08 ? 404 SER A OG 1 ATOM 3136 N N . PRO A 1 405 ? 2.722 107.233 99.658 1.00 111.09 ? 405 PRO A N 1 ATOM 3137 C CA . PRO A 1 405 ? 3.393 105.937 99.503 1.00 115.66 ? 405 PRO A CA 1 ATOM 3138 C C . PRO A 1 405 ? 2.541 104.947 98.697 1.00 117.58 ? 405 PRO A C 1 ATOM 3139 O O . PRO A 1 405 ? 2.891 103.767 98.584 1.00 112.28 ? 405 PRO A O 1 ATOM 3140 C CB . PRO A 1 405 ? 3.565 105.448 100.950 1.00 111.44 ? 405 PRO A CB 1 ATOM 3141 C CG . PRO A 1 405 ? 3.342 106.654 101.809 1.00 119.09 ? 405 PRO A CG 1 ATOM 3142 C CD . PRO A 1 405 ? 2.347 107.477 101.062 1.00 113.54 ? 405 PRO A CD 1 ATOM 3143 N N . ASN A 1 406 ? 1.425 105.436 98.157 1.00 114.69 ? 406 ASN A N 1 ATOM 3144 C CA . ASN A 1 406 ? 0.584 104.677 97.241 1.00 111.10 ? 406 ASN A CA 1 ATOM 3145 C C . ASN A 1 406 ? 0.941 105.034 95.796 1.00 107.26 ? 406 ASN A C 1 ATOM 3146 O O . ASN A 1 406 ? 0.584 104.319 94.856 1.00 104.78 ? 406 ASN A O 1 ATOM 3147 C CB . ASN A 1 406 ? -0.892 104.968 97.522 1.00 108.58 ? 406 ASN A CB 1 ATOM 3148 C CG . ASN A 1 406 ? -1.779 103.755 97.317 1.00 108.79 ? 406 ASN A CG 1 ATOM 3149 O OD1 . ASN A 1 406 ? -1.785 103.144 96.248 1.00 109.95 ? 406 ASN A OD1 1 ATOM 3150 N ND2 . ASN A 1 406 ? -2.546 103.406 98.344 1.00 104.64 ? 406 ASN A ND2 1 ATOM 3151 N N . VAL A 1 407 ? 1.647 106.153 95.638 1.00 104.29 ? 407 VAL A N 1 ATOM 3152 C CA . VAL A 1 407 ? 2.169 106.595 94.347 1.00 102.17 ? 407 VAL A CA 1 ATOM 3153 C C . VAL A 1 407 ? 3.676 106.817 94.504 1.00 108.58 ? 407 VAL A C 1 ATOM 3154 O O . VAL A 1 407 ? 4.160 107.955 94.468 1.00 106.00 ? 407 VAL A O 1 ATOM 3155 C CB . VAL A 1 407 ? 1.478 107.903 93.857 1.00 97.27 ? 407 VAL A CB 1 ATOM 3156 C CG1 . VAL A 1 407 ? 1.791 108.166 92.391 1.00 97.58 ? 407 VAL A CG1 1 ATOM 3157 C CG2 . VAL A 1 407 ? -0.031 107.844 94.062 1.00 95.55 ? 407 VAL A CG2 1 ATOM 3158 N N . LYS A 1 408 ? 4.406 105.715 94.694 1.00 110.89 ? 408 LYS A N 1 ATOM 3159 C CA . LYS A 1 408 ? 5.850 105.749 94.968 1.00 116.20 ? 408 LYS A CA 1 ATOM 3160 C C . LYS A 1 408 ? 6.641 106.546 93.939 1.00 119.22 ? 408 LYS A C 1 ATOM 3161 O O . LYS A 1 408 ? 7.348 107.493 94.294 1.00 127.06 ? 408 LYS A O 1 ATOM 3162 C CB . LYS A 1 408 ? 6.429 104.333 95.114 1.00 113.74 ? 408 LYS A CB 1 ATOM 3163 C CG . LYS A 1 408 ? 6.994 104.017 96.500 1.00 116.88 ? 408 LYS A CG 1 ATOM 3164 C CD . LYS A 1 408 ? 5.903 103.794 97.541 1.00 111.86 ? 408 LYS A CD 1 ATOM 3165 C CE . LYS A 1 408 ? 6.471 103.730 98.955 1.00 108.12 ? 408 LYS A CE 1 ATOM 3166 N NZ . LYS A 1 408 ? 7.291 102.508 99.196 1.00 100.55 ? 408 LYS A NZ 1 ATOM 3167 N N . ASN A 1 409 ? 6.521 106.165 92.671 1.00 108.04 ? 409 ASN A N 1 ATOM 3168 C CA . ASN A 1 409 ? 7.111 106.950 91.599 1.00 110.39 ? 409 ASN A CA 1 ATOM 3169 C C . ASN A 1 409 ? 6.110 108.023 91.186 1.00 107.58 ? 409 ASN A C 1 ATOM 3170 O O . ASN A 1 409 ? 4.924 107.926 91.507 1.00 105.33 ? 409 ASN A O 1 ATOM 3171 C CB . ASN A 1 409 ? 7.575 106.053 90.449 1.00 109.58 ? 409 ASN A CB 1 ATOM 3172 C CG . ASN A 1 409 ? 8.944 106.448 89.915 1.00 108.74 ? 409 ASN A CG 1 ATOM 3173 O OD1 . ASN A 1 409 ? 9.871 105.639 89.904 1.00 105.88 ? 409 ASN A OD1 1 ATOM 3174 N ND2 . ASN A 1 409 ? 9.079 107.696 89.479 1.00 102.11 ? 409 ASN A ND2 1 ATOM 3175 N N . ASN A 1 410 ? 6.604 109.040 90.485 1.00 105.73 ? 410 ASN A N 1 ATOM 3176 C CA . ASN A 1 410 ? 5.828 110.221 90.083 1.00 107.83 ? 410 ASN A CA 1 ATOM 3177 C C . ASN A 1 410 ? 4.462 109.938 89.442 1.00 106.07 ? 410 ASN A C 1 ATOM 3178 O O . ASN A 1 410 ? 3.603 110.824 89.399 1.00 100.33 ? 410 ASN A O 1 ATOM 3179 C CB . ASN A 1 410 ? 6.667 111.086 89.137 1.00 115.99 ? 410 ASN A CB 1 ATOM 3180 C CG . ASN A 1 410 ? 7.213 110.300 87.950 1.00 119.40 ? 410 ASN A CG 1 ATOM 3181 O OD1 . ASN A 1 410 ? 7.224 109.066 87.952 1.00 111.02 ? 410 ASN A OD1 1 ATOM 3182 N ND2 . ASN A 1 410 ? 7.673 111.019 86.930 1.00 118.85 ? 410 ASN A ND2 1 ATOM 3183 N N . ILE A 1 411 ? 4.270 108.719 88.941 1.00 100.52 ? 411 ILE A N 1 ATOM 3184 C CA . ILE A 1 411 ? 3.009 108.338 88.294 1.00 95.43 ? 411 ILE A CA 1 ATOM 3185 C C . ILE A 1 411 ? 2.314 107.155 88.967 1.00 89.82 ? 411 ILE A C 1 ATOM 3186 O O . ILE A 1 411 ? 2.948 106.368 89.671 1.00 92.01 ? 411 ILE A O 1 ATOM 3187 C CB . ILE A 1 411 ? 3.184 108.064 86.775 1.00 99.89 ? 411 ILE A CB 1 ATOM 3188 C CG1 . ILE A 1 411 ? 4.168 106.919 86.518 1.00 98.47 ? 411 ILE A CG1 1 ATOM 3189 C CG2 . ILE A 1 411 ? 3.639 109.320 86.066 1.00 111.63 ? 411 ILE A CG2 1 ATOM 3190 C CD1 . ILE A 1 411 ? 4.208 106.466 85.066 1.00 106.85 ? 411 ILE A CD1 1 ATOM 3191 N N . TYR A 1 412 ? 1.008 107.046 88.738 1.00 81.92 ? 412 TYR A N 1 ATOM 3192 C CA . TYR A 1 412 ? 0.194 105.991 89.333 1.00 84.69 ? 412 TYR A CA 1 ATOM 3193 C C . TYR A 1 412 ? -0.175 104.930 88.302 1.00 93.95 ? 412 TYR A C 1 ATOM 3194 O O . TYR A 1 412 ? -0.680 105.248 87.222 1.00 93.63 ? 412 TYR A O 1 ATOM 3195 C CB . TYR A 1 412 ? -1.065 106.588 89.966 1.00 82.97 ? 412 TYR A CB 1 ATOM 3196 C CG . TYR A 1 412 ? -1.917 105.603 90.740 1.00 80.01 ? 412 TYR A CG 1 ATOM 3197 C CD1 . TYR A 1 412 ? -1.486 105.083 91.961 1.00 85.09 ? 412 TYR A CD1 1 ATOM 3198 C CD2 . TYR A 1 412 ? -3.164 105.208 90.260 1.00 75.82 ? 412 TYR A CD2 1 ATOM 3199 C CE1 . TYR A 1 412 ? -2.270 104.183 92.676 1.00 88.94 ? 412 TYR A CE1 1 ATOM 3200 C CE2 . TYR A 1 412 ? -3.956 104.311 90.969 1.00 83.71 ? 412 TYR A CE2 1 ATOM 3201 C CZ . TYR A 1 412 ? -3.503 103.804 92.173 1.00 88.97 ? 412 TYR A CZ 1 ATOM 3202 O OH . TYR A 1 412 ? -4.285 102.918 92.874 1.00 86.17 ? 412 TYR A OH 1 ATOM 3203 N N . ASN A 1 413 ? 0.085 103.672 88.652 1.00 97.90 ? 413 ASN A N 1 ATOM 3204 C CA . ASN A 1 413 ? -0.173 102.531 87.775 1.00 92.34 ? 413 ASN A CA 1 ATOM 3205 C C . ASN A 1 413 ? -1.490 101.830 88.109 1.00 86.24 ? 413 ASN A C 1 ATOM 3206 O O . ASN A 1 413 ? -1.782 101.562 89.277 1.00 78.90 ? 413 ASN A O 1 ATOM 3207 C CB . ASN A 1 413 ? 0.991 101.532 87.842 1.00 99.48 ? 413 ASN A CB 1 ATOM 3208 C CG . ASN A 1 413 ? 2.226 102.008 87.084 1.00 103.42 ? 413 ASN A CG 1 ATOM 3209 O OD1 . ASN A 1 413 ? 2.560 101.459 86.032 1.00 110.54 ? 413 ASN A OD1 1 ATOM 3210 N ND2 . ASN A 1 413 ? 2.902 103.036 87.611 1.00 98.58 ? 413 ASN A ND2 1 ATOM 3211 N N . ALA A 1 414 ? -2.279 101.539 87.077 1.00 89.49 ? 414 ALA A N 1 ATOM 3212 C CA . ALA A 1 414 ? -3.568 100.869 87.247 1.00 93.30 ? 414 ALA A CA 1 ATOM 3213 C C . ALA A 1 414 ? -3.887 99.910 86.097 1.00 101.35 ? 414 ALA A C 1 ATOM 3214 O O . ALA A 1 414 ? -3.746 100.258 84.921 1.00 100.13 ? 414 ALA A O 1 ATOM 3215 C CB . ALA A 1 414 ? -4.679 101.891 87.414 1.00 80.83 ? 414 ALA A CB 1 ATOM 3216 N N . THR A 1 415 ? -4.326 98.706 86.457 1.00 102.06 ? 415 THR A N 1 ATOM 3217 C CA . THR A 1 415 ? -4.644 97.655 85.490 1.00 94.57 ? 415 THR A CA 1 ATOM 3218 C C . THR A 1 415 ? -6.155 97.451 85.358 1.00 95.91 ? 415 THR A C 1 ATOM 3219 O O . THR A 1 415 ? -6.902 97.653 86.317 1.00 97.60 ? 415 THR A O 1 ATOM 3220 C CB . THR A 1 415 ? -3.979 96.315 85.875 1.00 91.81 ? 415 THR A CB 1 ATOM 3221 O OG1 . THR A 1 415 ? -4.386 95.939 87.196 1.00 95.18 ? 415 THR A OG1 1 ATOM 3222 C CG2 . THR A 1 415 ? -2.459 96.431 85.834 1.00 91.57 ? 415 THR A CG2 1 ATOM 3223 N N . PHE A 1 416 ? -6.595 97.055 84.164 1.00 95.27 ? 416 PHE A N 1 ATOM 3224 C CA . PHE A 1 416 ? -8.019 96.854 83.872 1.00 95.69 ? 416 PHE A CA 1 ATOM 3225 C C . PHE A 1 416 ? -8.251 95.622 82.998 1.00 100.01 ? 416 PHE A C 1 ATOM 3226 O O . PHE A 1 416 ? -7.404 95.268 82.175 1.00 101.66 ? 416 PHE A O 1 ATOM 3227 C CB . PHE A 1 416 ? -8.603 98.085 83.172 1.00 92.92 ? 416 PHE A CB 1 ATOM 3228 C CG . PHE A 1 416 ? -8.573 99.337 84.003 1.00 105.10 ? 416 PHE A CG 1 ATOM 3229 C CD1 . PHE A 1 416 ? -9.644 99.664 84.831 1.00 103.70 ? 416 PHE A CD1 1 ATOM 3230 C CD2 . PHE A 1 416 ? -7.481 100.202 83.947 1.00 108.34 ? 416 PHE A CD2 1 ATOM 3231 C CE1 . PHE A 1 416 ? -9.624 100.826 85.597 1.00 100.36 ? 416 PHE A CE1 1 ATOM 3232 C CE2 . PHE A 1 416 ? -7.450 101.364 84.712 1.00 100.09 ? 416 PHE A CE2 1 ATOM 3233 C CZ . PHE A 1 416 ? -8.525 101.678 85.537 1.00 95.10 ? 416 PHE A CZ 1 ATOM 3234 N N . LEU A 1 417 ? -9.406 94.981 83.171 1.00 100.94 ? 417 LEU A N 1 ATOM 3235 C CA . LEU A 1 417 ? -9.770 93.809 82.372 1.00 96.08 ? 417 LEU A CA 1 ATOM 3236 C C . LEU A 1 417 ? -10.954 94.062 81.447 1.00 98.42 ? 417 LEU A C 1 ATOM 3237 O O . LEU A 1 417 ? -11.935 94.699 81.836 1.00 100.28 ? 417 LEU A O 1 ATOM 3238 C CB . LEU A 1 417 ? -10.065 92.597 83.264 1.00 87.92 ? 417 LEU A CB 1 ATOM 3239 C CG . LEU A 1 417 ? -8.907 91.663 83.632 1.00 92.78 ? 417 LEU A CG 1 ATOM 3240 C CD1 . LEU A 1 417 ? -9.343 90.656 84.687 1.00 100.46 ? 417 LEU A CD1 1 ATOM 3241 C CD2 . LEU A 1 417 ? -8.344 90.945 82.408 1.00 97.59 ? 417 LEU A CD2 1 ATOM 3242 N N . ALA A 1 418 ? -10.840 93.558 80.221 1.00 100.90 ? 418 ALA A N 1 ATOM 3243 C CA . ALA A 1 418 ? -11.943 93.531 79.269 1.00 94.19 ? 418 ALA A CA 1 ATOM 3244 C C . ALA A 1 418 ? -12.228 92.076 78.914 1.00 90.29 ? 418 ALA A C 1 ATOM 3245 O O . ALA A 1 418 ? -11.358 91.386 78.386 1.00 90.97 ? 418 ALA A O 1 ATOM 3246 C CB . ALA A 1 418 ? -11.597 94.338 78.029 1.00 87.31 ? 418 ALA A CB 1 ATOM 3247 N N . SER A 1 419 ? -13.439 91.610 79.220 1.00 95.55 ? 419 SER A N 1 ATOM 3248 C CA . SER A 1 419 ? -13.788 90.192 79.073 1.00 99.89 ? 419 SER A CA 1 ATOM 3249 C C . SER A 1 419 ? -14.912 89.921 78.065 1.00 105.97 ? 419 SER A C 1 ATOM 3250 O O . SER A 1 419 ? -15.766 90.778 77.822 1.00 106.30 ? 419 SER A O 1 ATOM 3251 C CB . SER A 1 419 ? -14.133 89.576 80.435 1.00 100.18 ? 419 SER A CB 1 ATOM 3252 O OG . SER A 1 419 ? -12.969 89.399 81.227 1.00 90.26 ? 419 SER A OG 1 ATOM 3253 N N . ASP A 1 420 ? -14.893 88.716 77.492 1.00 115.27 ? 420 ASP A N 1 ATOM 3254 C CA . ASP A 1 420 ? -15.864 88.291 76.479 1.00 114.84 ? 420 ASP A CA 1 ATOM 3255 C C . ASP A 1 420 ? -16.972 87.438 77.075 1.00 122.28 ? 420 ASP A C 1 ATOM 3256 O O . ASP A 1 420 ? -16.716 86.561 77.906 1.00 119.88 ? 420 ASP A O 1 ATOM 3257 C CB . ASP A 1 420 ? -15.173 87.486 75.374 1.00 109.78 ? 420 ASP A CB 1 ATOM 3258 C CG . ASP A 1 420 ? -14.071 88.262 74.679 1.00 108.73 ? 420 ASP A CG 1 ATOM 3259 O OD1 . ASP A 1 420 ? -13.937 89.480 74.920 1.00 103.38 ? 420 ASP A OD1 1 ATOM 3260 O OD2 . ASP A 1 420 ? -13.338 87.646 73.878 1.00 105.22 ? 420 ASP A OD2 1 ATOM 3261 N N . ASN A 1 421 ? -18.201 87.689 76.630 1.00 129.81 ? 421 ASN A N 1 ATOM 3262 C CA . ASN A 1 421 ? -19.351 86.878 77.028 1.00 136.57 ? 421 ASN A CA 1 ATOM 3263 C C . ASN A 1 421 ? -19.526 85.641 76.138 1.00 133.46 ? 421 ASN A C 1 ATOM 3264 O O . ASN A 1 421 ? -20.569 84.982 76.171 1.00 132.65 ? 421 ASN A O 1 ATOM 3265 C CB . ASN A 1 421 ? -20.634 87.724 77.061 1.00 136.68 ? 421 ASN A CB 1 ATOM 3266 C CG . ASN A 1 421 ? -21.036 88.244 75.689 1.00 133.61 ? 421 ASN A CG 1 ATOM 3267 O OD1 . ASN A 1 421 ? -20.188 88.522 74.840 1.00 127.96 ? 421 ASN A OD1 1 ATOM 3268 N ND2 . ASN A 1 421 ? -22.338 88.385 75.470 1.00 133.09 ? 421 ASN A ND2 1 ATOM 3269 N N . GLY A 1 422 ? -18.496 85.335 75.348 1.00 130.56 ? 422 GLY A N 1 ATOM 3270 C CA . GLY A 1 422 ? -18.485 84.150 74.495 1.00 127.65 ? 422 GLY A CA 1 ATOM 3271 C C . GLY A 1 422 ? -18.339 82.868 75.293 1.00 130.79 ? 422 GLY A C 1 ATOM 3272 O O . GLY A 1 422 ? -17.909 82.893 76.454 1.00 126.08 ? 422 GLY A O 1 ATOM 3273 N N . ILE A 1 423 ? -18.697 81.750 74.664 1.00 133.18 ? 423 ILE A N 1 ATOM 3274 C CA . ILE A 1 423 ? -18.682 80.430 75.312 1.00 135.85 ? 423 ILE A CA 1 ATOM 3275 C C . ILE A 1 423 ? -17.290 80.058 75.867 1.00 129.82 ? 423 ILE A C 1 ATOM 3276 O O . ILE A 1 423 ? -17.194 79.638 77.024 1.00 119.84 ? 423 ILE A O 1 ATOM 3277 C CB . ILE A 1 423 ? -19.274 79.303 74.391 1.00 137.45 ? 423 ILE A CB 1 ATOM 3278 C CG1 . ILE A 1 423 ? -20.543 79.782 73.652 1.00 131.65 ? 423 ILE A CG1 1 ATOM 3279 C CG2 . ILE A 1 423 ? -19.512 78.005 75.182 1.00 130.64 ? 423 ILE A CG2 1 ATOM 3280 C CD1 . ILE A 1 423 ? -21.740 80.161 74.542 1.00 118.93 ? 423 ILE A CD1 1 ATOM 3281 N N . PRO A 1 424 ? -16.217 80.195 75.049 1.00 127.22 ? 424 PRO A N 1 ATOM 3282 C CA . PRO A 1 424 ? -14.882 80.222 75.646 1.00 121.88 ? 424 PRO A CA 1 ATOM 3283 C C . PRO A 1 424 ? -14.448 81.674 75.915 1.00 123.15 ? 424 PRO A C 1 ATOM 3284 O O . PRO A 1 424 ? -13.935 82.337 75.006 1.00 118.94 ? 424 PRO A O 1 ATOM 3285 C CB . PRO A 1 424 ? -14.002 79.570 74.569 1.00 110.18 ? 424 PRO A CB 1 ATOM 3286 C CG . PRO A 1 424 ? -14.818 79.620 73.275 1.00 105.17 ? 424 PRO A CG 1 ATOM 3287 C CD . PRO A 1 424 ? -16.137 80.277 73.578 1.00 114.62 ? 424 PRO A CD 1 ATOM 3288 N N . PRO A 1 425 ? -14.649 82.168 77.156 1.00 124.83 ? 425 PRO A N 1 ATOM 3289 C CA . PRO A 1 425 ? -14.474 83.594 77.452 1.00 115.98 ? 425 PRO A CA 1 ATOM 3290 C C . PRO A 1 425 ? -13.008 84.025 77.469 1.00 110.05 ? 425 PRO A C 1 ATOM 3291 O O . PRO A 1 425 ? -12.183 83.412 78.152 1.00 107.04 ? 425 PRO A O 1 ATOM 3292 C CB . PRO A 1 425 ? -15.098 83.750 78.850 1.00 110.72 ? 425 PRO A CB 1 ATOM 3293 C CG . PRO A 1 425 ? -15.767 82.437 79.155 1.00 113.10 ? 425 PRO A CG 1 ATOM 3294 C CD . PRO A 1 425 ? -15.028 81.417 78.364 1.00 118.47 ? 425 PRO A CD 1 ATOM 3295 N N . MET A 1 426 ? -12.700 85.076 76.713 1.00 102.57 ? 426 MET A N 1 ATOM 3296 C CA . MET A 1 426 ? -11.337 85.595 76.607 1.00 99.82 ? 426 MET A CA 1 ATOM 3297 C C . MET A 1 426 ? -11.244 86.957 77.292 1.00 97.50 ? 426 MET A C 1 ATOM 3298 O O . MET A 1 426 ? -12.269 87.572 77.588 1.00 99.54 ? 426 MET A O 1 ATOM 3299 C CB . MET A 1 426 ? -10.918 85.710 75.136 1.00 99.14 ? 426 MET A CB 1 ATOM 3300 C CG . MET A 1 426 ? -11.208 84.477 74.277 1.00 98.75 ? 426 MET A CG 1 ATOM 3301 S SD . MET A 1 426 ? -10.093 83.082 74.542 1.00 87.29 ? 426 MET A SD 1 ATOM 3302 C CE . MET A 1 426 ? -8.646 83.599 73.621 1.00 84.61 ? 426 MET A CE 1 ATOM 3303 N N . SER A 1 427 ? -10.020 87.423 77.539 1.00 97.96 ? 427 SER A N 1 ATOM 3304 C CA . SER A 1 427 ? -9.792 88.691 78.243 1.00 92.45 ? 427 SER A CA 1 ATOM 3305 C C . SER A 1 427 ? -8.423 89.312 77.955 1.00 91.26 ? 427 SER A C 1 ATOM 3306 O O . SER A 1 427 ? -7.437 88.602 77.747 1.00 89.65 ? 427 SER A O 1 ATOM 3307 C CB . SER A 1 427 ? -9.956 88.497 79.752 1.00 92.71 ? 427 SER A CB 1 ATOM 3308 O OG . SER A 1 427 ? -9.130 87.439 80.196 1.00 95.26 ? 427 SER A OG 1 ATOM 3309 N N . GLY A 1 428 ? -8.375 90.643 77.959 1.00 93.60 ? 428 GLY A N 1 ATOM 3310 C CA . GLY A 1 428 ? -7.134 91.390 77.753 1.00 96.21 ? 428 GLY A CA 1 ATOM 3311 C C . GLY A 1 428 ? -6.886 92.410 78.850 1.00 97.52 ? 428 GLY A C 1 ATOM 3312 O O . GLY A 1 428 ? -7.812 93.097 79.290 1.00 92.43 ? 428 GLY A O 1 ATOM 3313 N N . THR A 1 429 ? -5.629 92.515 79.282 1.00 104.52 ? 429 THR A N 1 ATOM 3314 C CA . THR A 1 429 ? -5.256 93.381 80.403 1.00 104.05 ? 429 THR A CA 1 ATOM 3315 C C . THR A 1 429 ? -4.681 94.727 79.961 1.00 107.36 ? 429 THR A C 1 ATOM 3316 O O . THR A 1 429 ? -3.553 94.807 79.466 1.00 111.09 ? 429 THR A O 1 ATOM 3317 C CB . THR A 1 429 ? -4.285 92.665 81.372 1.00 105.45 ? 429 THR A CB 1 ATOM 3318 O OG1 . THR A 1 429 ? -4.865 91.411 81.769 1.00 115.29 ? 429 THR A OG1 1 ATOM 3319 C CG2 . THR A 1 429 ? -4.004 93.543 82.597 1.00 105.85 ? 429 THR A CG2 1 ATOM 3320 N N . GLY A 1 430 ? -5.474 95.779 80.159 1.00 107.57 ? 430 GLY A N 1 ATOM 3321 C CA . GLY A 1 430 ? -5.087 97.143 79.805 1.00 103.25 ? 430 GLY A CA 1 ATOM 3322 C C . GLY A 1 430 ? -4.458 97.910 80.952 1.00 95.50 ? 430 GLY A C 1 ATOM 3323 O O . GLY A 1 430 ? -4.848 97.756 82.112 1.00 87.91 ? 430 GLY A O 1 ATOM 3324 N N . THR A 1 431 ? -3.482 98.746 80.615 1.00 100.18 ? 431 THR A N 1 ATOM 3325 C CA . THR A 1 431 ? -2.760 99.548 81.594 1.00 98.59 ? 431 THR A CA 1 ATOM 3326 C C . THR A 1 431 ? -3.105 101.028 81.427 1.00 101.52 ? 431 THR A C 1 ATOM 3327 O O . THR A 1 431 ? -3.235 101.521 80.304 1.00 97.04 ? 431 THR A O 1 ATOM 3328 C CB . THR A 1 431 ? -1.220 99.315 81.478 1.00 104.09 ? 431 THR A CB 1 ATOM 3329 O OG1 . THR A 1 431 ? -0.873 98.074 82.106 1.00 107.63 ? 431 THR A OG1 1 ATOM 3330 C CG2 . THR A 1 431 ? -0.426 100.430 82.155 1.00 102.23 ? 431 THR A CG2 1 ATOM 3331 N N . LEU A 1 432 ? -3.277 101.719 82.553 1.00 101.81 ? 432 LEU A N 1 ATOM 3332 C CA . LEU A 1 432 ? -3.393 103.174 82.560 1.00 93.51 ? 432 LEU A CA 1 ATOM 3333 C C . LEU A 1 432 ? -2.383 103.780 83.531 1.00 88.83 ? 432 LEU A C 1 ATOM 3334 O O . LEU A 1 432 ? -2.410 103.497 84.732 1.00 88.90 ? 432 LEU A O 1 ATOM 3335 C CB . LEU A 1 432 ? -4.824 103.620 82.887 1.00 88.85 ? 432 LEU A CB 1 ATOM 3336 C CG . LEU A 1 432 ? -5.087 105.128 82.996 1.00 88.04 ? 432 LEU A CG 1 ATOM 3337 C CD1 . LEU A 1 432 ? -6.343 105.533 82.241 1.00 92.28 ? 432 LEU A CD1 1 ATOM 3338 C CD2 . LEU A 1 432 ? -5.163 105.566 84.452 1.00 83.72 ? 432 LEU A CD2 1 ATOM 3339 N N . GLN A 1 433 ? -1.489 104.602 82.990 1.00 90.65 ? 433 GLN A N 1 ATOM 3340 C CA . GLN A 1 433 ? -0.479 105.297 83.780 1.00 97.38 ? 433 GLN A CA 1 ATOM 3341 C C . GLN A 1 433 ? -0.679 106.804 83.657 1.00 100.50 ? 433 GLN A C 1 ATOM 3342 O O . GLN A 1 433 ? -0.611 107.361 82.559 1.00 103.26 ? 433 GLN A O 1 ATOM 3343 C CB . GLN A 1 433 ? 0.930 104.897 83.330 1.00 99.87 ? 433 GLN A CB 1 ATOM 3344 C CG . GLN A 1 433 ? 1.308 103.455 83.666 1.00 104.10 ? 433 GLN A CG 1 ATOM 3345 C CD . GLN A 1 433 ? 2.656 103.035 83.094 1.00 111.09 ? 433 GLN A CD 1 ATOM 3346 O OE1 . GLN A 1 433 ? 3.570 103.848 82.949 1.00 110.54 ? 433 GLN A OE1 1 ATOM 3347 N NE2 . GLN A 1 433 ? 2.784 101.753 82.774 1.00 106.42 ? 433 GLN A NE2 1 ATOM 3348 N N . ILE A 1 434 ? -0.933 107.454 84.791 1.00 102.94 ? 434 ILE A N 1 ATOM 3349 C CA . ILE A 1 434 ? -1.271 108.878 84.808 1.00 100.58 ? 434 ILE A CA 1 ATOM 3350 C C . ILE A 1 434 ? -0.213 109.756 85.468 1.00 95.18 ? 434 ILE A C 1 ATOM 3351 O O . ILE A 1 434 ? 0.211 109.504 86.598 1.00 83.19 ? 434 ILE A O 1 ATOM 3352 C CB . ILE A 1 434 ? -2.654 109.145 85.450 1.00 92.92 ? 434 ILE A CB 1 ATOM 3353 C CG1 . ILE A 1 434 ? -2.905 108.179 86.615 1.00 82.57 ? 434 ILE A CG1 1 ATOM 3354 C CG2 . ILE A 1 434 ? -3.749 109.039 84.391 1.00 96.07 ? 434 ILE A CG2 1 ATOM 3355 C CD1 . ILE A 1 434 ? -4.132 108.500 87.444 1.00 84.31 ? 434 ILE A CD1 1 ATOM 3356 N N . TYR A 1 435 ? 0.199 110.790 84.737 1.00 107.38 ? 435 TYR A N 1 ATOM 3357 C CA . TYR A 1 435 ? 1.188 111.753 85.207 1.00 109.63 ? 435 TYR A CA 1 ATOM 3358 C C . TYR A 1 435 ? 0.548 112.816 86.087 1.00 107.11 ? 435 TYR A C 1 ATOM 3359 O O . TYR A 1 435 ? -0.308 113.581 85.634 1.00 108.81 ? 435 TYR A O 1 ATOM 3360 C CB . TYR A 1 435 ? 1.921 112.393 84.023 1.00 111.16 ? 435 TYR A CB 1 ATOM 3361 C CG . TYR A 1 435 ? 3.017 111.520 83.455 1.00 124.20 ? 435 TYR A CG 1 ATOM 3362 C CD1 . TYR A 1 435 ? 4.359 111.768 83.756 1.00 126.36 ? 435 TYR A CD1 1 ATOM 3363 C CD2 . TYR A 1 435 ? 2.715 110.433 82.628 1.00 122.80 ? 435 TYR A CD2 1 ATOM 3364 C CE1 . TYR A 1 435 ? 5.373 110.960 83.244 1.00 122.49 ? 435 TYR A CE1 1 ATOM 3365 C CE2 . TYR A 1 435 ? 3.721 109.620 82.111 1.00 118.13 ? 435 TYR A CE2 1 ATOM 3366 C CZ . TYR A 1 435 ? 5.045 109.890 82.423 1.00 118.24 ? 435 TYR A CZ 1 ATOM 3367 O OH . TYR A 1 435 ? 6.039 109.090 81.912 1.00 103.83 ? 435 TYR A OH 1 ATOM 3368 N N . LEU A 1 436 ? 0.969 112.852 87.349 1.00 99.89 ? 436 LEU A N 1 ATOM 3369 C CA . LEU A 1 436 ? 0.408 113.776 88.328 1.00 95.16 ? 436 LEU A CA 1 ATOM 3370 C C . LEU A 1 436 ? 1.335 114.964 88.566 1.00 101.24 ? 436 LEU A C 1 ATOM 3371 O O . LEU A 1 436 ? 2.443 114.805 89.087 1.00 104.34 ? 436 LEU A O 1 ATOM 3372 C CB . LEU A 1 436 ? 0.101 113.051 89.644 1.00 82.04 ? 436 LEU A CB 1 ATOM 3373 C CG . LEU A 1 436 ? -0.948 111.932 89.614 1.00 77.99 ? 436 LEU A CG 1 ATOM 3374 C CD1 . LEU A 1 436 ? -0.873 111.092 90.879 1.00 67.30 ? 436 LEU A CD1 1 ATOM 3375 C CD2 . LEU A 1 436 ? -2.359 112.480 89.408 1.00 78.90 ? 436 LEU A CD2 1 ATOM 3376 N N . LEU A 1 437 ? 0.876 116.149 88.170 1.00 93.78 ? 437 LEU A N 1 ATOM 3377 C CA . LEU A 1 437 ? 1.646 117.376 88.349 1.00 99.12 ? 437 LEU A CA 1 ATOM 3378 C C . LEU A 1 437 ? 1.520 117.889 89.778 1.00 100.26 ? 437 LEU A C 1 ATOM 3379 O O . LEU A 1 437 ? 0.414 117.997 90.311 1.00 97.96 ? 437 LEU A O 1 ATOM 3380 C CB . LEU A 1 437 ? 1.203 118.457 87.357 1.00 102.37 ? 437 LEU A CB 1 ATOM 3381 C CG . LEU A 1 437 ? 1.579 118.268 85.886 1.00 99.15 ? 437 LEU A CG 1 ATOM 3382 C CD1 . LEU A 1 437 ? 0.458 117.574 85.125 1.00 92.49 ? 437 LEU A CD1 1 ATOM 3383 C CD2 . LEU A 1 437 ? 1.900 119.613 85.251 1.00 114.16 ? 437 LEU A CD2 1 ATOM 3384 N N . ASP A 1 438 ? 2.663 118.200 90.387 1.00 96.44 ? 438 ASP A N 1 ATOM 3385 C CA . ASP A 1 438 ? 2.714 118.667 91.771 1.00 88.88 ? 438 ASP A CA 1 ATOM 3386 C C . ASP A 1 438 ? 2.227 120.107 91.897 1.00 87.07 ? 438 ASP A C 1 ATOM 3387 O O . ASP A 1 438 ? 2.824 121.024 91.330 1.00 89.44 ? 438 ASP A O 1 ATOM 3388 C CB . ASP A 1 438 ? 4.139 118.532 92.328 1.00 89.19 ? 438 ASP A CB 1 ATOM 3389 C CG . ASP A 1 438 ? 4.274 119.074 93.745 1.00 85.93 ? 438 ASP A CG 1 ATOM 3390 O OD1 . ASP A 1 438 ? 3.406 118.773 94.593 1.00 78.32 ? 438 ASP A OD1 1 ATOM 3391 O OD2 . ASP A 1 438 ? 5.257 119.797 94.013 1.00 85.18 ? 438 ASP A OD2 1 ATOM 3392 N N . ILE A 1 439 ? 1.130 120.289 92.629 1.00 86.13 ? 439 ILE A N 1 ATOM 3393 C CA . ILE A 1 439 ? 0.640 121.623 92.985 1.00 87.28 ? 439 ILE A CA 1 ATOM 3394 C C . ILE A 1 439 ? 1.016 121.939 94.429 1.00 86.13 ? 439 ILE A C 1 ATOM 3395 O O . ILE A 1 439 ? 1.225 121.025 95.232 1.00 87.16 ? 439 ILE A O 1 ATOM 3396 C CB . ILE A 1 439 ? -0.898 121.776 92.791 1.00 81.99 ? 439 ILE A CB 1 ATOM 3397 C CG1 . ILE A 1 439 ? -1.664 120.657 93.513 1.00 78.36 ? 439 ILE A CG1 1 ATOM 3398 C CG2 . ILE A 1 439 ? -1.247 121.837 91.303 1.00 84.38 ? 439 ILE A CG2 1 ATOM 3399 C CD1 . ILE A 1 439 ? -3.140 120.944 93.724 1.00 70.90 ? 439 ILE A CD1 1 ATOM 3400 N N . ASN A 1 440 ? 1.112 123.226 94.752 1.00 82.42 ? 440 ASN A N 1 ATOM 3401 C CA . ASN A 1 440 ? 1.417 123.643 96.115 1.00 82.07 ? 440 ASN A CA 1 ATOM 3402 C C . ASN A 1 440 ? 0.199 123.497 97.021 1.00 78.18 ? 440 ASN A C 1 ATOM 3403 O O . ASN A 1 440 ? -0.620 124.414 97.141 1.00 75.26 ? 440 ASN A O 1 ATOM 3404 C CB . ASN A 1 440 ? 1.957 125.075 96.149 1.00 82.35 ? 440 ASN A CB 1 ATOM 3405 C CG . ASN A 1 440 ? 2.591 125.428 97.482 1.00 74.22 ? 440 ASN A CG 1 ATOM 3406 O OD1 . ASN A 1 440 ? 3.323 124.630 98.068 1.00 68.83 ? 440 ASN A OD1 1 ATOM 3407 N ND2 . ASN A 1 440 ? 2.316 126.631 97.965 1.00 76.83 ? 440 ASN A ND2 1 ATOM 3408 N N . ASP A 1 441 ? 0.084 122.326 97.639 1.00 77.92 ? 441 ASP A N 1 ATOM 3409 C CA . ASP A 1 441 ? -1.025 122.020 98.537 1.00 76.54 ? 441 ASP A CA 1 ATOM 3410 C C . ASP A 1 441 ? -0.545 121.353 99.827 1.00 76.34 ? 441 ASP A C 1 ATOM 3411 O O . ASP A 1 441 ? -1.286 120.606 100.468 1.00 74.83 ? 441 ASP A O 1 ATOM 3412 C CB . ASP A 1 441 ? -2.088 121.167 97.826 1.00 87.74 ? 441 ASP A CB 1 ATOM 3413 C CG . ASP A 1 441 ? -1.518 119.896 97.202 1.00 86.31 ? 441 ASP A CG 1 ATOM 3414 O OD1 . ASP A 1 441 ? -2.297 119.160 96.559 1.00 80.06 ? 441 ASP A OD1 1 ATOM 3415 O OD2 . ASP A 1 441 ? -0.307 119.620 97.344 1.00 83.44 ? 441 ASP A OD2 1 ATOM 3416 N N . ASN A 1 442 ? 0.704 121.626 100.193 1.00 74.21 ? 442 ASN A N 1 ATOM 3417 C CA . ASN A 1 442 ? 1.249 121.182 101.468 1.00 79.70 ? 442 ASN A CA 1 ATOM 3418 C C . ASN A 1 442 ? 1.846 122.339 102.247 1.00 81.81 ? 442 ASN A C 1 ATOM 3419 O O . ASN A 1 442 ? 2.734 123.040 101.755 1.00 79.65 ? 442 ASN A O 1 ATOM 3420 C CB . ASN A 1 442 ? 2.292 120.081 101.273 1.00 81.46 ? 442 ASN A CB 1 ATOM 3421 C CG . ASN A 1 442 ? 1.677 118.768 100.856 1.00 79.86 ? 442 ASN A CG 1 ATOM 3422 O OD1 . ASN A 1 442 ? 1.187 118.627 99.736 1.00 87.12 ? 442 ASN A OD1 1 ATOM 3423 N ND2 . ASN A 1 442 ? 1.700 117.793 101.755 1.00 72.78 ? 442 ASN A ND2 1 ATOM 3424 N N . ALA A 1 443 ? 1.341 122.536 103.459 1.00 77.30 ? 443 ALA A N 1 ATOM 3425 C CA . ALA A 1 443 ? 1.828 123.580 104.346 1.00 73.33 ? 443 ALA A CA 1 ATOM 3426 C C . ALA A 1 443 ? 3.184 123.181 104.929 1.00 80.80 ? 443 ALA A C 1 ATOM 3427 O O . ALA A 1 443 ? 3.340 122.052 105.403 1.00 91.30 ? 443 ALA A O 1 ATOM 3428 C CB . ALA A 1 443 ? 0.823 123.830 105.453 1.00 76.52 ? 443 ALA A CB 1 ATOM 3429 N N . PRO A 1 444 ? 4.175 124.097 104.876 1.00 74.38 ? 444 PRO A N 1 ATOM 3430 C CA . PRO A 1 444 ? 5.501 123.843 105.446 1.00 74.26 ? 444 PRO A CA 1 ATOM 3431 C C . PRO A 1 444 ? 5.461 123.636 106.959 1.00 74.58 ? 444 PRO A C 1 ATOM 3432 O O . PRO A 1 444 ? 4.652 124.260 107.648 1.00 74.95 ? 444 PRO A O 1 ATOM 3433 C CB . PRO A 1 444 ? 6.282 125.120 105.112 1.00 64.55 ? 444 PRO A CB 1 ATOM 3434 C CG . PRO A 1 444 ? 5.539 125.746 103.990 1.00 70.27 ? 444 PRO A CG 1 ATOM 3435 C CD . PRO A 1 444 ? 4.105 125.427 104.247 1.00 70.33 ? 444 PRO A CD 1 ATOM 3436 N N . GLN A 1 445 ? 6.325 122.755 107.456 1.00 77.99 ? 445 GLN A N 1 ATOM 3437 C CA . GLN A 1 445 ? 6.442 122.486 108.887 1.00 81.73 ? 445 GLN A CA 1 ATOM 3438 C C . GLN A 1 445 ? 7.856 122.794 109.359 1.00 82.82 ? 445 GLN A C 1 ATOM 3439 O O . GLN A 1 445 ? 8.760 122.965 108.545 1.00 88.73 ? 445 GLN A O 1 ATOM 3440 C CB . GLN A 1 445 ? 6.090 121.027 109.198 1.00 90.43 ? 445 GLN A CB 1 ATOM 3441 C CG . GLN A 1 445 ? 4.671 120.611 108.806 1.00 89.88 ? 445 GLN A CG 1 ATOM 3442 C CD . GLN A 1 445 ? 3.592 121.386 109.545 1.00 88.75 ? 445 GLN A CD 1 ATOM 3443 O OE1 . GLN A 1 445 ? 3.688 121.619 110.752 1.00 92.46 ? 445 GLN A OE1 1 ATOM 3444 N NE2 . GLN A 1 445 ? 2.552 121.783 108.821 1.00 75.23 ? 445 GLN A NE2 1 ATOM 3445 N N . VAL A 1 446 ? 8.043 122.869 110.672 1.00 81.79 ? 446 VAL A N 1 ATOM 3446 C CA . VAL A 1 446 ? 9.367 123.107 111.241 1.00 90.22 ? 446 VAL A CA 1 ATOM 3447 C C . VAL A 1 446 ? 10.102 121.775 111.457 1.00 97.40 ? 446 VAL A C 1 ATOM 3448 O O . VAL A 1 446 ? 9.554 120.846 112.061 1.00 97.36 ? 446 VAL A O 1 ATOM 3449 C CB . VAL A 1 446 ? 9.291 123.982 112.534 1.00 83.61 ? 446 VAL A CB 1 ATOM 3450 C CG1 . VAL A 1 446 ? 8.430 123.322 113.616 1.00 83.98 ? 446 VAL A CG1 1 ATOM 3451 C CG2 . VAL A 1 446 ? 10.684 124.319 113.056 1.00 88.06 ? 446 VAL A CG2 1 ATOM 3452 N N . LEU A 1 447 ? 11.330 121.687 110.942 1.00 98.45 ? 447 LEU A N 1 ATOM 3453 C CA . LEU A 1 447 ? 12.117 120.442 110.982 1.00 108.81 ? 447 LEU A CA 1 ATOM 3454 C C . LEU A 1 447 ? 12.588 120.057 112.395 1.00 110.62 ? 447 LEU A C 1 ATOM 3455 O O . LEU A 1 447 ? 12.277 118.955 112.857 1.00 114.53 ? 447 LEU A O 1 ATOM 3456 C CB . LEU A 1 447 ? 13.284 120.480 109.972 1.00 107.29 ? 447 LEU A CB 1 ATOM 3457 C CG . LEU A 1 447 ? 14.184 119.265 109.655 1.00 107.82 ? 447 LEU A CG 1 ATOM 3458 C CD1 . LEU A 1 447 ? 15.367 119.130 110.626 1.00 108.66 ? 447 LEU A CD1 1 ATOM 3459 C CD2 . LEU A 1 447 ? 13.408 117.947 109.542 1.00 105.51 ? 447 LEU A CD2 1 ATOM 3460 N N . PRO A 1 448 ? 13.344 120.944 113.083 1.00 100.45 ? 448 PRO A N 1 ATOM 3461 C CA . PRO A 1 448 ? 13.626 120.621 114.479 1.00 97.47 ? 448 PRO A CA 1 ATOM 3462 C C . PRO A 1 448 ? 12.367 120.830 115.316 1.00 99.02 ? 448 PRO A C 1 ATOM 3463 O O . PRO A 1 448 ? 12.153 121.911 115.870 1.00 101.08 ? 448 PRO A O 1 ATOM 3464 C CB . PRO A 1 448 ? 14.726 121.624 114.866 1.00 98.81 ? 448 PRO A CB 1 ATOM 3465 C CG . PRO A 1 448 ? 15.172 122.257 113.579 1.00 94.74 ? 448 PRO A CG 1 ATOM 3466 C CD . PRO A 1 448 ? 13.982 122.212 112.690 1.00 94.68 ? 448 PRO A CD 1 ATOM 3467 N N . GLN A 1 449 ? 11.534 119.793 115.377 1.00 99.75 ? 449 GLN A N 1 ATOM 3468 C CA . GLN A 1 449 ? 10.253 119.851 116.074 1.00 99.22 ? 449 GLN A CA 1 ATOM 3469 C C . GLN A 1 449 ? 10.449 119.943 117.585 1.00 104.06 ? 449 GLN A C 1 ATOM 3470 O O . GLN A 1 449 ? 9.683 120.617 118.274 1.00 101.12 ? 449 GLN A O 1 ATOM 3471 C CB . GLN A 1 449 ? 9.403 118.629 115.719 1.00 98.11 ? 449 GLN A CB 1 ATOM 3472 C CG . GLN A 1 449 ? 7.935 118.745 116.110 1.00 104.07 ? 449 GLN A CG 1 ATOM 3473 C CD . GLN A 1 449 ? 7.188 117.426 116.001 1.00 111.89 ? 449 GLN A CD 1 ATOM 3474 O OE1 . GLN A 1 449 ? 6.081 117.372 115.467 1.00 106.07 ? 449 GLN A OE1 1 ATOM 3475 N NE2 . GLN A 1 449 ? 7.792 116.355 116.509 1.00 109.22 ? 449 GLN A NE2 1 ATOM 3476 N N . GLU A 1 450 ? 11.483 119.269 118.086 1.00 111.01 ? 450 GLU A N 1 ATOM 3477 C CA . GLU A 1 450 ? 11.793 119.260 119.515 1.00 114.29 ? 450 GLU A CA 1 ATOM 3478 C C . GLU A 1 450 ? 13.193 119.814 119.794 1.00 115.85 ? 450 GLU A C 1 ATOM 3479 O O . GLU A 1 450 ? 14.044 119.125 120.366 1.00 120.74 ? 450 GLU A O 1 ATOM 3480 C CB . GLU A 1 450 ? 11.644 117.845 120.096 1.00 124.31 ? 450 GLU A CB 1 ATOM 3481 C CG . GLU A 1 450 ? 10.226 117.260 120.039 1.00 124.67 ? 450 GLU A CG 1 ATOM 3482 C CD . GLU A 1 450 ? 9.236 117.959 120.968 1.00 122.20 ? 450 GLU A CD 1 ATOM 3483 O OE1 . GLU A 1 450 ? 9.653 118.479 122.028 1.00 113.97 ? 450 GLU A OE1 1 ATOM 3484 O OE2 . GLU A 1 450 ? 8.030 117.977 120.636 1.00 114.47 ? 450 GLU A OE2 1 ATOM 3485 N N . ALA A 1 451 ? 13.423 121.059 119.380 1.00 115.09 ? 451 ALA A N 1 ATOM 3486 C CA . ALA A 1 451 ? 14.682 121.754 119.659 1.00 127.44 ? 451 ALA A CA 1 ATOM 3487 C C . ALA A 1 451 ? 14.606 122.448 121.017 1.00 127.87 ? 451 ALA A C 1 ATOM 3488 O O . ALA A 1 451 ? 13.767 123.330 121.230 1.00 120.09 ? 451 ALA A O 1 ATOM 3489 C CB . ALA A 1 451 ? 15.007 122.752 118.552 1.00 118.98 ? 451 ALA A CB 1 ATOM 3490 N N . GLU A 1 452 ? 15.478 122.034 121.934 1.00 131.45 ? 452 GLU A N 1 ATOM 3491 C CA . GLU A 1 452 ? 15.428 122.490 123.324 1.00 129.96 ? 452 GLU A CA 1 ATOM 3492 C C . GLU A 1 452 ? 16.827 122.794 123.861 1.00 137.18 ? 452 GLU A C 1 ATOM 3493 O O . GLU A 1 452 ? 17.681 121.901 123.929 1.00 140.53 ? 452 GLU A O 1 ATOM 3494 C CB . GLU A 1 452 ? 14.736 121.440 124.205 1.00 126.44 ? 452 GLU A CB 1 ATOM 3495 C CG . GLU A 1 452 ? 13.386 120.950 123.666 1.00 129.17 ? 452 GLU A CG 1 ATOM 3496 C CD . GLU A 1 452 ? 12.799 119.787 124.454 1.00 139.28 ? 452 GLU A CD 1 ATOM 3497 O OE1 . GLU A 1 452 ? 13.491 119.239 125.342 1.00 141.69 ? 452 GLU A OE1 1 ATOM 3498 O OE2 . GLU A 1 452 ? 11.634 119.420 124.181 1.00 138.34 ? 452 GLU A OE2 1 ATOM 3499 N N . THR A 1 453 ? 17.056 124.056 124.230 1.00 139.22 ? 453 THR A N 1 ATOM 3500 C CA . THR A 1 453 ? 18.346 124.493 124.781 1.00 141.20 ? 453 THR A CA 1 ATOM 3501 C C . THR A 1 453 ? 18.166 125.374 126.027 1.00 145.85 ? 453 THR A C 1 ATOM 3502 O O . THR A 1 453 ? 17.107 125.978 126.219 1.00 145.64 ? 453 THR A O 1 ATOM 3503 C CB . THR A 1 453 ? 19.216 125.224 123.721 1.00 137.77 ? 453 THR A CB 1 ATOM 3504 O OG1 . THR A 1 453 ? 18.418 126.174 123.004 1.00 134.28 ? 453 THR A OG1 1 ATOM 3505 C CG2 . THR A 1 453 ? 19.825 124.230 122.733 1.00 124.39 ? 453 THR A CG2 1 ATOM 3506 N N . CYS A 1 454 ? 19.206 125.434 126.864 1.00 149.22 ? 454 CYS A N 1 ATOM 3507 C CA . CYS A 1 454 ? 19.180 126.188 128.129 1.00 145.20 ? 454 CYS A CA 1 ATOM 3508 C C . CYS A 1 454 ? 19.227 127.708 127.938 1.00 147.01 ? 454 CYS A C 1 ATOM 3509 O O . CYS A 1 454 ? 19.397 128.195 126.816 1.00 149.44 ? 454 CYS A O 1 ATOM 3510 C CB . CYS A 1 454 ? 20.328 125.742 129.042 1.00 140.71 ? 454 CYS A CB 1 ATOM 3511 S SG . CYS A 1 454 ? 20.099 124.110 129.783 1.00 151.04 ? 454 CYS A SG 1 ATOM 3512 N N . GLU A 1 455 ? 19.082 128.447 129.041 1.00 143.01 ? 455 GLU A N 1 ATOM 3513 C CA . GLU A 1 455 ? 19.014 129.916 129.007 1.00 145.08 ? 455 GLU A CA 1 ATOM 3514 C C . GLU A 1 455 ? 20.358 130.601 128.748 1.00 147.19 ? 455 GLU A C 1 ATOM 3515 O O . GLU A 1 455 ? 20.879 131.342 129.590 1.00 143.76 ? 455 GLU A O 1 ATOM 3516 C CB . GLU A 1 455 ? 18.331 130.474 130.264 1.00 143.22 ? 455 GLU A CB 1 ATOM 3517 C CG . GLU A 1 455 ? 16.907 130.968 130.010 1.00 146.33 ? 455 GLU A CG 1 ATOM 3518 C CD . GLU A 1 455 ? 16.113 131.241 131.282 1.00 144.72 ? 455 GLU A CD 1 ATOM 3519 O OE1 . GLU A 1 455 ? 16.509 130.757 132.366 1.00 148.87 ? 455 GLU A OE1 1 ATOM 3520 O OE2 . GLU A 1 455 ? 15.079 131.942 131.190 1.00 134.43 ? 455 GLU A OE2 1 ATOM 3521 N N . THR A 1 456 ? 20.901 130.338 127.562 1.00 148.51 ? 456 THR A N 1 ATOM 3522 C CA . THR A 1 456 ? 22.098 131.001 127.078 1.00 153.65 ? 456 THR A CA 1 ATOM 3523 C C . THR A 1 456 ? 21.686 131.895 125.910 1.00 158.75 ? 456 THR A C 1 ATOM 3524 O O . THR A 1 456 ? 21.242 131.388 124.873 1.00 152.65 ? 456 THR A O 1 ATOM 3525 C CB . THR A 1 456 ? 23.162 129.980 126.599 1.00 151.98 ? 456 THR A CB 1 ATOM 3526 O OG1 . THR A 1 456 ? 23.261 128.901 127.537 1.00 143.30 ? 456 THR A OG1 1 ATOM 3527 C CG2 . THR A 1 456 ? 24.528 130.646 126.442 1.00 154.37 ? 456 THR A CG2 1 ATOM 3528 N N . PRO A 1 457 ? 21.799 133.230 126.082 1.00 164.97 ? 457 PRO A N 1 ATOM 3529 C CA . PRO A 1 457 ? 21.597 134.165 124.964 1.00 160.44 ? 457 PRO A CA 1 ATOM 3530 C C . PRO A 1 457 ? 22.733 134.062 123.931 1.00 162.87 ? 457 PRO A C 1 ATOM 3531 O O . PRO A 1 457 ? 23.314 135.074 123.523 1.00 158.11 ? 457 PRO A O 1 ATOM 3532 C CB . PRO A 1 457 ? 21.572 135.538 125.648 1.00 151.45 ? 457 PRO A CB 1 ATOM 3533 C CG . PRO A 1 457 ? 22.322 135.352 126.916 1.00 157.76 ? 457 PRO A CG 1 ATOM 3534 C CD . PRO A 1 457 ? 22.093 133.933 127.346 1.00 159.58 ? 457 PRO A CD 1 ATOM 3535 N N . GLU A 1 458 ? 23.019 132.826 123.523 1.00 161.00 ? 458 GLU A N 1 ATOM 3536 C CA . GLU A 1 458 ? 24.069 132.485 122.568 1.00 153.84 ? 458 GLU A CA 1 ATOM 3537 C C . GLU A 1 458 ? 23.679 132.953 121.161 1.00 157.50 ? 458 GLU A C 1 ATOM 3538 O O . GLU A 1 458 ? 22.564 132.670 120.706 1.00 153.08 ? 458 GLU A O 1 ATOM 3539 C CB . GLU A 1 458 ? 24.286 130.968 122.603 1.00 145.57 ? 458 GLU A CB 1 ATOM 3540 C CG . GLU A 1 458 ? 25.416 130.428 121.739 1.00 143.18 ? 458 GLU A CG 1 ATOM 3541 C CD . GLU A 1 458 ? 25.546 128.914 121.825 1.00 137.29 ? 458 GLU A CD 1 ATOM 3542 O OE1 . GLU A 1 458 ? 24.654 128.257 122.419 1.00 135.83 ? 458 GLU A OE1 1 ATOM 3543 O OE2 . GLU A 1 458 ? 26.545 128.376 121.293 1.00 132.39 ? 458 GLU A OE2 1 ATOM 3544 N N . PRO A 1 459 ? 24.595 133.673 120.471 1.00 160.05 ? 459 PRO A N 1 ATOM 3545 C CA . PRO A 1 459 ? 24.344 134.314 119.167 1.00 153.73 ? 459 PRO A CA 1 ATOM 3546 C C . PRO A 1 459 ? 23.677 133.421 118.115 1.00 145.17 ? 459 PRO A C 1 ATOM 3547 O O . PRO A 1 459 ? 22.970 133.928 117.240 1.00 135.45 ? 459 PRO A O 1 ATOM 3548 C CB . PRO A 1 459 ? 25.746 134.720 118.703 1.00 149.49 ? 459 PRO A CB 1 ATOM 3549 C CG . PRO A 1 459 ? 26.494 134.947 119.961 1.00 153.79 ? 459 PRO A CG 1 ATOM 3550 C CD . PRO A 1 459 ? 25.976 133.922 120.934 1.00 156.52 ? 459 PRO A CD 1 ATOM 3551 N N . ASN A 1 460 ? 23.909 132.111 118.205 1.00 150.43 ? 460 ASN A N 1 ATOM 3552 C CA . ASN A 1 460 ? 23.297 131.136 117.303 1.00 143.43 ? 460 ASN A CA 1 ATOM 3553 C C . ASN A 1 460 ? 23.080 129.784 117.997 1.00 139.03 ? 460 ASN A C 1 ATOM 3554 O O . ASN A 1 460 ? 23.864 128.845 117.819 1.00 140.33 ? 460 ASN A O 1 ATOM 3555 C CB . ASN A 1 460 ? 24.141 130.982 116.025 1.00 136.28 ? 460 ASN A CB 1 ATOM 3556 C CG . ASN A 1 460 ? 23.402 130.254 114.905 1.00 133.76 ? 460 ASN A CG 1 ATOM 3557 O OD1 . ASN A 1 460 ? 24.022 129.779 113.953 1.00 136.68 ? 460 ASN A OD1 1 ATOM 3558 N ND2 . ASN A 1 460 ? 22.077 130.168 115.011 1.00 125.52 ? 460 ASN A ND2 1 ATOM 3559 N N . SER A 1 461 ? 22.015 129.701 118.793 1.00 131.39 ? 461 SER A N 1 ATOM 3560 C CA . SER A 1 461 ? 21.671 128.472 119.512 1.00 133.92 ? 461 SER A CA 1 ATOM 3561 C C . SER A 1 461 ? 20.784 127.542 118.688 1.00 127.22 ? 461 SER A C 1 ATOM 3562 O O . SER A 1 461 ? 21.084 126.355 118.550 1.00 129.74 ? 461 SER A O 1 ATOM 3563 C CB . SER A 1 461 ? 20.997 128.789 120.853 1.00 139.87 ? 461 SER A CB 1 ATOM 3564 O OG . SER A 1 461 ? 21.945 128.877 121.903 1.00 145.36 ? 461 SER A OG 1 ATOM 3565 N N . ILE A 1 462 ? 19.696 128.087 118.146 1.00 119.63 ? 462 ILE A N 1 ATOM 3566 C CA . ILE A 1 462 ? 18.701 127.282 117.438 1.00 115.33 ? 462 ILE A CA 1 ATOM 3567 C C . ILE A 1 462 ? 18.627 127.637 115.952 1.00 109.03 ? 462 ILE A C 1 ATOM 3568 O O . ILE A 1 462 ? 18.381 128.789 115.588 1.00 107.28 ? 462 ILE A O 1 ATOM 3569 C CB . ILE A 1 462 ? 17.291 127.396 118.094 1.00 112.39 ? 462 ILE A CB 1 ATOM 3570 C CG1 . ILE A 1 462 ? 17.367 127.095 119.598 1.00 115.97 ? 462 ILE A CG1 1 ATOM 3571 C CG2 . ILE A 1 462 ? 16.291 126.461 117.404 1.00 103.66 ? 462 ILE A CG2 1 ATOM 3572 C CD1 . ILE A 1 462 ? 16.184 127.602 120.408 1.00 100.22 ? 462 ILE A CD1 1 ATOM 3573 N N . ASN A 1 463 ? 18.858 126.635 115.106 1.00 111.37 ? 463 ASN A N 1 ATOM 3574 C CA . ASN A 1 463 ? 18.682 126.765 113.662 1.00 111.03 ? 463 ASN A CA 1 ATOM 3575 C C . ASN A 1 463 ? 17.552 125.860 113.180 1.00 101.42 ? 463 ASN A C 1 ATOM 3576 O O . ASN A 1 463 ? 17.532 124.666 113.484 1.00 103.98 ? 463 ASN A O 1 ATOM 3577 C CB . ASN A 1 463 ? 19.983 126.436 112.922 1.00 117.25 ? 463 ASN A CB 1 ATOM 3578 C CG . ASN A 1 463 ? 21.012 127.555 113.011 1.00 122.02 ? 463 ASN A CG 1 ATOM 3579 O OD1 . ASN A 1 463 ? 20.735 128.703 112.659 1.00 114.22 ? 463 ASN A OD1 1 ATOM 3580 N ND2 . ASN A 1 463 ? 22.213 127.216 113.467 1.00 125.12 ? 463 ASN A ND2 1 ATOM 3581 N N . ILE A 1 464 ? 16.614 126.437 112.435 1.00 92.16 ? 464 ILE A N 1 ATOM 3582 C CA . ILE A 1 464 ? 15.427 125.707 111.987 1.00 93.48 ? 464 ILE A CA 1 ATOM 3583 C C . ILE A 1 464 ? 15.295 125.641 110.466 1.00 104.43 ? 464 ILE A C 1 ATOM 3584 O O . ILE A 1 464 ? 15.635 126.593 109.759 1.00 107.46 ? 464 ILE A O 1 ATOM 3585 C CB . ILE A 1 464 ? 14.123 126.279 112.601 1.00 94.10 ? 464 ILE A CB 1 ATOM 3586 C CG1 . ILE A 1 464 ? 14.055 127.803 112.424 1.00 97.05 ? 464 ILE A CG1 1 ATOM 3587 C CG2 . ILE A 1 464 ? 14.015 125.889 114.071 1.00 92.74 ? 464 ILE A CG2 1 ATOM 3588 C CD1 . ILE A 1 464 ? 12.663 128.385 112.552 1.00 78.39 ? 464 ILE A CD1 1 ATOM 3589 N N . THR A 1 465 ? 14.804 124.502 109.979 1.00 105.78 ? 465 THR A N 1 ATOM 3590 C CA . THR A 1 465 ? 14.551 124.297 108.552 1.00 102.24 ? 465 THR A CA 1 ATOM 3591 C C . THR A 1 465 ? 13.079 123.918 108.351 1.00 101.11 ? 465 THR A C 1 ATOM 3592 O O . THR A 1 465 ? 12.300 123.913 109.309 1.00 94.58 ? 465 THR A O 1 ATOM 3593 C CB . THR A 1 465 ? 15.496 123.221 107.926 1.00 107.64 ? 465 THR A CB 1 ATOM 3594 O OG1 . THR A 1 465 ? 14.781 122.000 107.698 1.00 107.22 ? 465 THR A OG1 1 ATOM 3595 C CG2 . THR A 1 465 ? 16.700 122.942 108.821 1.00 106.01 ? 465 THR A CG2 1 ATOM 3596 N N . ALA A 1 466 ? 12.704 123.602 107.112 1.00 102.73 ? 466 ALA A N 1 ATOM 3597 C CA . ALA A 1 466 ? 11.313 123.288 106.783 1.00 103.61 ? 466 ALA A CA 1 ATOM 3598 C C . ALA A 1 466 ? 11.096 121.860 106.268 1.00 96.83 ? 466 ALA A C 1 ATOM 3599 O O . ALA A 1 466 ? 11.947 121.304 105.573 1.00 102.14 ? 466 ALA A O 1 ATOM 3600 C CB . ALA A 1 466 ? 10.767 124.303 105.785 1.00 93.91 ? 466 ALA A CB 1 ATOM 3601 N N . LEU A 1 467 ? 9.952 121.279 106.625 1.00 89.68 ? 467 LEU A N 1 ATOM 3602 C CA . LEU A 1 467 ? 9.510 119.997 106.075 1.00 88.16 ? 467 LEU A CA 1 ATOM 3603 C C . LEU A 1 467 ? 8.346 120.209 105.114 1.00 88.80 ? 467 LEU A C 1 ATOM 3604 O O . LEU A 1 467 ? 7.276 120.673 105.515 1.00 87.17 ? 467 LEU A O 1 ATOM 3605 C CB . LEU A 1 467 ? 9.095 119.029 107.190 1.00 102.36 ? 467 LEU A CB 1 ATOM 3606 C CG . LEU A 1 467 ? 10.074 117.939 107.638 1.00 114.37 ? 467 LEU A CG 1 ATOM 3607 C CD1 . LEU A 1 467 ? 9.641 117.355 108.980 1.00 106.86 ? 467 LEU A CD1 1 ATOM 3608 C CD2 . LEU A 1 467 ? 10.203 116.836 106.588 1.00 108.45 ? 467 LEU A CD2 1 ATOM 3609 N N . ASP A 1 468 ? 8.562 119.866 103.847 1.00 95.13 ? 468 ASP A N 1 ATOM 3610 C CA . ASP A 1 468 ? 7.552 120.045 102.808 1.00 86.57 ? 468 ASP A CA 1 ATOM 3611 C C . ASP A 1 468 ? 7.413 118.777 101.972 1.00 90.74 ? 468 ASP A C 1 ATOM 3612 O O . ASP A 1 468 ? 8.414 118.182 101.566 1.00 97.43 ? 468 ASP A O 1 ATOM 3613 C CB . ASP A 1 468 ? 7.922 121.232 101.912 1.00 79.97 ? 468 ASP A CB 1 ATOM 3614 C CG . ASP A 1 468 ? 6.714 121.870 101.246 1.00 80.88 ? 468 ASP A CG 1 ATOM 3615 O OD1 . ASP A 1 468 ? 5.595 121.321 101.338 1.00 84.47 ? 468 ASP A OD1 1 ATOM 3616 O OD2 . ASP A 1 468 ? 6.882 122.939 100.624 1.00 80.34 ? 468 ASP A OD2 1 ATOM 3617 N N . TYR A 1 469 ? 6.172 118.368 101.717 1.00 86.85 ? 469 TYR A N 1 ATOM 3618 C CA . TYR A 1 469 ? 5.911 117.168 100.921 1.00 86.12 ? 469 TYR A CA 1 ATOM 3619 C C . TYR A 1 469 ? 5.724 117.484 99.434 1.00 86.79 ? 469 TYR A C 1 ATOM 3620 O O . TYR A 1 469 ? 5.027 116.764 98.714 1.00 85.14 ? 469 TYR A O 1 ATOM 3621 C CB . TYR A 1 469 ? 4.707 116.394 101.473 1.00 81.26 ? 469 TYR A CB 1 ATOM 3622 C CG . TYR A 1 469 ? 4.843 115.959 102.919 1.00 79.54 ? 469 TYR A CG 1 ATOM 3623 C CD1 . TYR A 1 469 ? 3.740 115.963 103.770 1.00 76.50 ? 469 TYR A CD1 1 ATOM 3624 C CD2 . TYR A 1 469 ? 6.073 115.546 103.436 1.00 87.06 ? 469 TYR A CD2 1 ATOM 3625 C CE1 . TYR A 1 469 ? 3.855 115.563 105.095 1.00 80.21 ? 469 TYR A CE1 1 ATOM 3626 C CE2 . TYR A 1 469 ? 6.199 115.148 104.760 1.00 84.62 ? 469 TYR A CE2 1 ATOM 3627 C CZ . TYR A 1 469 ? 5.087 115.159 105.582 1.00 81.10 ? 469 TYR A CZ 1 ATOM 3628 O OH . TYR A 1 469 ? 5.212 114.766 106.892 1.00 85.07 ? 469 TYR A OH 1 ATOM 3629 N N . ASP A 1 470 ? 6.363 118.560 98.984 1.00 84.52 ? 470 ASP A N 1 ATOM 3630 C CA . ASP A 1 470 ? 6.319 118.972 97.585 1.00 86.81 ? 470 ASP A CA 1 ATOM 3631 C C . ASP A 1 470 ? 7.728 119.155 97.022 1.00 84.93 ? 470 ASP A C 1 ATOM 3632 O O . ASP A 1 470 ? 8.676 119.430 97.763 1.00 81.15 ? 470 ASP A O 1 ATOM 3633 C CB . ASP A 1 470 ? 5.518 120.271 97.431 1.00 88.11 ? 470 ASP A CB 1 ATOM 3634 C CG . ASP A 1 470 ? 4.056 120.119 97.828 1.00 83.40 ? 470 ASP A CG 1 ATOM 3635 O OD1 . ASP A 1 470 ? 3.508 121.066 98.429 1.00 82.36 ? 470 ASP A OD1 1 ATOM 3636 O OD2 . ASP A 1 470 ? 3.451 119.065 97.537 1.00 81.33 ? 470 ASP A OD2 1 ATOM 3637 N N . ILE A 1 471 ? 7.853 118.991 95.709 1.00 84.77 ? 471 ILE A N 1 ATOM 3638 C CA . ILE A 1 471 ? 9.120 119.206 95.011 1.00 86.16 ? 471 ILE A CA 1 ATOM 3639 C C . ILE A 1 471 ? 9.105 120.545 94.278 1.00 79.71 ? 471 ILE A C 1 ATOM 3640 O O . ILE A 1 471 ? 8.034 121.102 94.020 1.00 79.14 ? 471 ILE A O 1 ATOM 3641 C CB . ILE A 1 471 ? 9.443 118.061 94.014 1.00 93.82 ? 471 ILE A CB 1 ATOM 3642 C CG1 . ILE A 1 471 ? 8.247 117.789 93.088 1.00 86.70 ? 471 ILE A CG1 1 ATOM 3643 C CG2 . ILE A 1 471 ? 9.876 116.800 94.772 1.00 93.05 ? 471 ILE A CG2 1 ATOM 3644 C CD1 . ILE A 1 471 ? 8.611 117.162 91.754 1.00 86.27 ? 471 ILE A CD1 1 ATOM 3645 N N . ASP A 1 472 ? 10.296 121.043 93.947 1.00 80.64 ? 472 ASP A N 1 ATOM 3646 C CA . ASP A 1 472 ? 10.483 122.338 93.277 1.00 88.77 ? 472 ASP A CA 1 ATOM 3647 C C . ASP A 1 472 ? 9.462 122.607 92.165 1.00 86.54 ? 472 ASP A C 1 ATOM 3648 O O . ASP A 1 472 ? 9.123 121.698 91.404 1.00 88.92 ? 472 ASP A O 1 ATOM 3649 C CB . ASP A 1 472 ? 11.909 122.447 92.717 1.00 95.00 ? 472 ASP A CB 1 ATOM 3650 C CG . ASP A 1 472 ? 12.982 122.357 93.797 1.00 101.31 ? 472 ASP A CG 1 ATOM 3651 O OD1 . ASP A 1 472 ? 12.640 122.195 94.991 1.00 95.35 ? 472 ASP A OD1 1 ATOM 3652 O OD2 . ASP A 1 472 ? 14.177 122.448 93.444 1.00 101.98 ? 472 ASP A OD2 1 ATOM 3653 N N . PRO A 1 473 ? 8.969 123.858 92.064 1.00 89.24 ? 473 PRO A N 1 ATOM 3654 C CA . PRO A 1 473 ? 9.344 125.012 92.886 1.00 94.88 ? 473 PRO A CA 1 ATOM 3655 C C . PRO A 1 473 ? 8.481 125.180 94.145 1.00 89.21 ? 473 PRO A C 1 ATOM 3656 O O . PRO A 1 473 ? 8.644 126.160 94.881 1.00 86.72 ? 473 PRO A O 1 ATOM 3657 C CB . PRO A 1 473 ? 9.135 126.192 91.931 1.00 102.89 ? 473 PRO A CB 1 ATOM 3658 C CG . PRO A 1 473 ? 8.103 125.713 90.923 1.00 95.02 ? 473 PRO A CG 1 ATOM 3659 C CD . PRO A 1 473 ? 7.946 124.219 91.066 1.00 88.73 ? 473 PRO A CD 1 ATOM 3660 N N . ASN A 1 474 ? 7.599 124.211 94.392 1.00 91.66 ? 474 ASN A N 1 ATOM 3661 C CA . ASN A 1 474 ? 6.634 124.257 95.497 1.00 83.64 ? 474 ASN A CA 1 ATOM 3662 C C . ASN A 1 474 ? 7.249 124.013 96.883 1.00 79.35 ? 474 ASN A C 1 ATOM 3663 O O . ASN A 1 474 ? 6.543 123.696 97.845 1.00 71.87 ? 474 ASN A O 1 ATOM 3664 C CB . ASN A 1 474 ? 5.482 123.283 95.226 1.00 80.29 ? 474 ASN A CB 1 ATOM 3665 C CG . ASN A 1 474 ? 4.908 123.436 93.827 1.00 82.52 ? 474 ASN A CG 1 ATOM 3666 O OD1 . ASN A 1 474 ? 4.348 124.477 93.482 1.00 74.31 ? 474 ASN A OD1 1 ATOM 3667 N ND2 . ASN A 1 474 ? 5.051 122.396 93.014 1.00 85.38 ? 474 ASN A ND2 1 ATOM 3668 N N . ALA A 1 475 ? 8.569 124.158 96.961 1.00 83.35 ? 475 ALA A N 1 ATOM 3669 C CA . ALA A 1 475 ? 9.296 124.183 98.221 1.00 85.37 ? 475 ALA A CA 1 ATOM 3670 C C . ALA A 1 475 ? 10.190 125.424 98.222 1.00 93.91 ? 475 ALA A C 1 ATOM 3671 O O . ALA A 1 475 ? 9.868 126.422 98.871 1.00 91.77 ? 475 ALA A O 1 ATOM 3672 C CB . ALA A 1 475 ? 10.117 122.910 98.401 1.00 80.91 ? 475 ALA A CB 1 ATOM 3673 N N . GLY A 1 476 ? 11.295 125.352 97.475 1.00 100.68 ? 476 GLY A N 1 ATOM 3674 C CA . GLY A 1 476 ? 12.219 126.474 97.274 1.00 98.13 ? 476 GLY A CA 1 ATOM 3675 C C . GLY A 1 476 ? 12.701 127.152 98.547 1.00 104.03 ? 476 GLY A C 1 ATOM 3676 O O . GLY A 1 476 ? 12.891 126.487 99.569 1.00 103.13 ? 476 GLY A O 1 ATOM 3677 N N . PRO A 1 477 ? 12.931 128.480 98.483 1.00 107.46 ? 477 PRO A N 1 ATOM 3678 C CA . PRO A 1 477 ? 13.212 129.295 99.672 1.00 106.50 ? 477 PRO A CA 1 ATOM 3679 C C . PRO A 1 477 ? 11.982 129.496 100.570 1.00 98.24 ? 477 PRO A C 1 ATOM 3680 O O . PRO A 1 477 ? 10.908 129.863 100.084 1.00 93.03 ? 477 PRO A O 1 ATOM 3681 C CB . PRO A 1 477 ? 13.674 130.640 99.082 1.00 107.50 ? 477 PRO A CB 1 ATOM 3682 C CG . PRO A 1 477 ? 13.938 130.374 97.621 1.00 104.98 ? 477 PRO A CG 1 ATOM 3683 C CD . PRO A 1 477 ? 12.994 129.283 97.249 1.00 101.16 ? 477 PRO A CD 1 ATOM 3684 N N . PHE A 1 478 ? 12.156 129.256 101.870 1.00 95.51 ? 478 PHE A N 1 ATOM 3685 C CA . PHE A 1 478 ? 11.078 129.393 102.855 1.00 91.73 ? 478 PHE A CA 1 ATOM 3686 C C . PHE A 1 478 ? 11.238 130.641 103.721 1.00 91.63 ? 478 PHE A C 1 ATOM 3687 O O . PHE A 1 478 ? 12.324 130.910 104.239 1.00 95.53 ? 478 PHE A O 1 ATOM 3688 C CB . PHE A 1 478 ? 11.016 128.164 103.768 1.00 91.25 ? 478 PHE A CB 1 ATOM 3689 C CG . PHE A 1 478 ? 10.738 126.874 103.048 1.00 95.08 ? 478 PHE A CG 1 ATOM 3690 C CD1 . PHE A 1 478 ? 11.783 126.027 102.686 1.00 100.82 ? 478 PHE A CD1 1 ATOM 3691 C CD2 . PHE A 1 478 ? 9.432 126.496 102.747 1.00 89.97 ? 478 PHE A CD2 1 ATOM 3692 C CE1 . PHE A 1 478 ? 11.533 124.827 102.025 1.00 102.47 ? 478 PHE A CE1 1 ATOM 3693 C CE2 . PHE A 1 478 ? 9.171 125.300 102.086 1.00 91.94 ? 478 PHE A CE2 1 ATOM 3694 C CZ . PHE A 1 478 ? 10.224 124.464 101.725 1.00 101.40 ? 478 PHE A CZ 1 ATOM 3695 N N . ALA A 1 479 ? 10.149 131.388 103.889 1.00 87.07 ? 479 ALA A N 1 ATOM 3696 C CA . ALA A 1 479 ? 10.146 132.566 104.756 1.00 83.54 ? 479 ALA A CA 1 ATOM 3697 C C . ALA A 1 479 ? 9.759 132.197 106.189 1.00 75.84 ? 479 ALA A C 1 ATOM 3698 O O . ALA A 1 479 ? 8.761 131.510 106.410 1.00 70.56 ? 479 ALA A O 1 ATOM 3699 C CB . ALA A 1 479 ? 9.213 133.635 104.201 1.00 76.85 ? 479 ALA A CB 1 ATOM 3700 N N . PHE A 1 480 ? 10.557 132.654 107.153 1.00 76.19 ? 480 PHE A N 1 ATOM 3701 C CA . PHE A 1 480 ? 10.328 132.361 108.572 1.00 76.78 ? 480 PHE A CA 1 ATOM 3702 C C . PHE A 1 480 ? 9.997 133.633 109.352 1.00 80.27 ? 480 PHE A C 1 ATOM 3703 O O . PHE A 1 480 ? 10.771 134.595 109.342 1.00 84.22 ? 480 PHE A O 1 ATOM 3704 C CB . PHE A 1 480 ? 11.550 131.668 109.182 1.00 75.42 ? 480 PHE A CB 1 ATOM 3705 C CG . PHE A 1 480 ? 11.822 130.303 108.616 1.00 81.54 ? 480 PHE A CG 1 ATOM 3706 C CD1 . PHE A 1 480 ? 12.507 130.154 107.411 1.00 89.19 ? 480 PHE A CD1 1 ATOM 3707 C CD2 . PHE A 1 480 ? 11.398 129.162 109.289 1.00 76.02 ? 480 PHE A CD2 1 ATOM 3708 C CE1 . PHE A 1 480 ? 12.760 128.889 106.883 1.00 88.51 ? 480 PHE A CE1 1 ATOM 3709 C CE2 . PHE A 1 480 ? 11.647 127.891 108.771 1.00 81.52 ? 480 PHE A CE2 1 ATOM 3710 C CZ . PHE A 1 480 ? 12.329 127.755 107.565 1.00 85.95 ? 480 PHE A CZ 1 ATOM 3711 N N . ASP A 1 481 ? 8.849 133.630 110.028 1.00 73.89 ? 481 ASP A N 1 ATOM 3712 C CA . ASP A 1 481 ? 8.348 134.819 110.725 1.00 70.80 ? 481 ASP A CA 1 ATOM 3713 C C . ASP A 1 481 ? 7.681 134.494 112.056 1.00 63.19 ? 481 ASP A C 1 ATOM 3714 O O . ASP A 1 481 ? 6.979 133.491 112.177 1.00 63.54 ? 481 ASP A O 1 ATOM 3715 C CB . ASP A 1 481 ? 7.347 135.572 109.842 1.00 70.03 ? 481 ASP A CB 1 ATOM 3716 C CG . ASP A 1 481 ? 8.010 136.311 108.697 1.00 80.54 ? 481 ASP A CG 1 ATOM 3717 O OD1 . ASP A 1 481 ? 8.875 137.176 108.962 1.00 87.99 ? 481 ASP A OD1 1 ATOM 3718 O OD2 . ASP A 1 481 ? 7.653 136.036 107.530 1.00 76.00 ? 481 ASP A OD2 1 ATOM 3719 N N . LEU A 1 482 ? 7.899 135.357 113.045 1.00 54.62 ? 482 LEU A N 1 ATOM 3720 C CA . LEU A 1 482 ? 7.177 135.278 114.308 1.00 47.44 ? 482 LEU A CA 1 ATOM 3721 C C . LEU A 1 482 ? 5.869 136.070 114.249 1.00 48.30 ? 482 LEU A C 1 ATOM 3722 O O . LEU A 1 482 ? 5.828 137.156 113.671 1.00 51.48 ? 482 LEU A O 1 ATOM 3723 C CB . LEU A 1 482 ? 8.042 135.777 115.465 1.00 51.45 ? 482 LEU A CB 1 ATOM 3724 C CG . LEU A 1 482 ? 8.867 134.730 116.208 1.00 48.53 ? 482 LEU A CG 1 ATOM 3725 C CD1 . LEU A 1 482 ? 10.273 134.684 115.665 1.00 55.83 ? 482 LEU A CD1 1 ATOM 3726 C CD2 . LEU A 1 482 ? 8.893 135.056 117.686 1.00 56.24 ? 482 LEU A CD2 1 ATOM 3727 N N . PRO A 1 483 ? 4.792 135.520 114.838 1.00 41.73 ? 483 PRO A N 1 ATOM 3728 C CA . PRO A 1 483 ? 3.497 136.192 114.910 1.00 39.54 ? 483 PRO A CA 1 ATOM 3729 C C . PRO A 1 483 ? 3.527 137.472 115.739 1.00 43.60 ? 483 PRO A C 1 ATOM 3730 O O . PRO A 1 483 ? 4.327 137.595 116.671 1.00 44.29 ? 483 PRO A O 1 ATOM 3731 C CB . PRO A 1 483 ? 2.602 135.160 115.604 1.00 41.68 ? 483 PRO A CB 1 ATOM 3732 C CG . PRO A 1 483 ? 3.293 133.866 115.431 1.00 45.81 ? 483 PRO A CG 1 ATOM 3733 C CD . PRO A 1 483 ? 4.742 134.187 115.457 1.00 45.52 ? 483 PRO A CD 1 ATOM 3734 N N . LEU A 1 484 ? 2.650 138.411 115.395 1.00 41.49 ? 484 LEU A N 1 ATOM 3735 C CA . LEU A 1 484 ? 2.520 139.663 116.136 1.00 40.48 ? 484 LEU A CA 1 ATOM 3736 C C . LEU A 1 484 ? 1.816 139.450 117.476 1.00 48.90 ? 484 LEU A C 1 ATOM 3737 O O . LEU A 1 484 ? 2.244 139.993 118.497 1.00 53.90 ? 484 LEU A O 1 ATOM 3738 C CB . LEU A 1 484 ? 1.792 140.721 115.299 1.00 28.85 ? 484 LEU A CB 1 ATOM 3739 C CG . LEU A 1 484 ? 2.495 141.235 114.038 1.00 29.86 ? 484 LEU A CG 1 ATOM 3740 C CD1 . LEU A 1 484 ? 1.586 142.176 113.272 1.00 27.76 ? 484 LEU A CD1 1 ATOM 3741 C CD2 . LEU A 1 484 ? 3.810 141.926 114.371 1.00 34.58 ? 484 LEU A CD2 1 ATOM 3742 N N . SER A 1 485 ? 0.743 138.659 117.460 1.00 44.84 ? 485 SER A N 1 ATOM 3743 C CA . SER A 1 485 ? 0.021 138.271 118.672 1.00 38.18 ? 485 SER A CA 1 ATOM 3744 C C . SER A 1 485 ? 0.081 136.748 118.849 1.00 34.87 ? 485 SER A C 1 ATOM 3745 O O . SER A 1 485 ? -0.080 136.017 117.874 1.00 37.76 ? 485 SER A O 1 ATOM 3746 C CB . SER A 1 485 ? -1.428 138.762 118.620 1.00 33.59 ? 485 SER A CB 1 ATOM 3747 O OG . SER A 1 485 ? -2.092 138.272 117.471 1.00 37.99 ? 485 SER A OG 1 ATOM 3748 N N . PRO A 1 486 ? 0.305 136.262 120.090 1.00 38.07 ? 486 PRO A N 1 ATOM 3749 C CA . PRO A 1 486 ? 0.362 137.003 121.354 1.00 40.32 ? 486 PRO A CA 1 ATOM 3750 C C . PRO A 1 486 ? 1.576 137.917 121.436 1.00 43.62 ? 486 PRO A C 1 ATOM 3751 O O . PRO A 1 486 ? 2.642 137.584 120.917 1.00 45.50 ? 486 PRO A O 1 ATOM 3752 C CB . PRO A 1 486 ? 0.451 135.898 122.409 1.00 45.57 ? 486 PRO A CB 1 ATOM 3753 C CG . PRO A 1 486 ? 1.056 134.752 121.704 1.00 49.86 ? 486 PRO A CG 1 ATOM 3754 C CD . PRO A 1 486 ? 0.565 134.825 120.291 1.00 41.42 ? 486 PRO A CD 1 ATOM 3755 N N . VAL A 1 487 ? 1.397 139.062 122.086 1.00 49.75 ? 487 VAL A N 1 ATOM 3756 C CA . VAL A 1 487 ? 2.405 140.122 122.118 1.00 47.62 ? 487 VAL A CA 1 ATOM 3757 C C . VAL A 1 487 ? 3.712 139.661 122.769 1.00 45.56 ? 487 VAL A C 1 ATOM 3758 O O . VAL A 1 487 ? 4.790 140.138 122.415 1.00 43.37 ? 487 VAL A O 1 ATOM 3759 C CB . VAL A 1 487 ? 1.871 141.383 122.847 1.00 43.87 ? 487 VAL A CB 1 ATOM 3760 C CG1 . VAL A 1 487 ? 2.660 142.620 122.432 1.00 59.12 ? 487 VAL A CG1 1 ATOM 3761 C CG2 . VAL A 1 487 ? 0.382 141.588 122.562 1.00 40.33 ? 487 VAL A CG2 1 ATOM 3762 N N . THR A 1 488 ? 3.599 138.713 123.696 1.00 47.84 ? 488 THR A N 1 ATOM 3763 C CA . THR A 1 488 ? 4.729 138.257 124.510 1.00 52.99 ? 488 THR A CA 1 ATOM 3764 C C . THR A 1 488 ? 5.816 137.514 123.731 1.00 50.47 ? 488 THR A C 1 ATOM 3765 O O . THR A 1 488 ? 6.984 137.543 124.121 1.00 56.74 ? 488 THR A O 1 ATOM 3766 C CB . THR A 1 488 ? 4.265 137.368 125.697 1.00 47.69 ? 488 THR A CB 1 ATOM 3767 O OG1 . THR A 1 488 ? 3.692 136.154 125.200 1.00 52.93 ? 488 THR A OG1 1 ATOM 3768 C CG2 . THR A 1 488 ? 3.237 138.094 126.556 1.00 46.90 ? 488 THR A CG2 1 ATOM 3769 N N . ILE A 1 489 ? 5.438 136.861 122.635 1.00 44.42 ? 489 ILE A N 1 ATOM 3770 C CA . ILE A 1 489 ? 6.358 135.956 121.941 1.00 52.39 ? 489 ILE A CA 1 ATOM 3771 C C . ILE A 1 489 ? 7.431 136.672 121.124 1.00 54.79 ? 489 ILE A C 1 ATOM 3772 O O . ILE A 1 489 ? 8.605 136.303 121.188 1.00 65.22 ? 489 ILE A O 1 ATOM 3773 C CB . ILE A 1 489 ? 5.629 134.869 121.097 1.00 51.53 ? 489 ILE A CB 1 ATOM 3774 C CG1 . ILE A 1 489 ? 4.848 135.489 119.938 1.00 49.54 ? 489 ILE A CG1 1 ATOM 3775 C CG2 . ILE A 1 489 ? 4.730 134.005 121.991 1.00 56.00 ? 489 ILE A CG2 1 ATOM 3776 C CD1 . ILE A 1 489 ? 4.279 134.475 118.984 1.00 49.80 ? 489 ILE A CD1 1 ATOM 3777 N N . LYS A 1 490 ? 7.039 137.695 120.372 1.00 56.37 ? 490 LYS A N 1 ATOM 3778 C CA . LYS A 1 490 ? 8.008 138.474 119.608 1.00 60.08 ? 490 LYS A CA 1 ATOM 3779 C C . LYS A 1 490 ? 8.843 139.336 120.558 1.00 59.62 ? 490 LYS A C 1 ATOM 3780 O O . LYS A 1 490 ? 9.933 139.783 120.206 1.00 64.81 ? 490 LYS A O 1 ATOM 3781 C CB . LYS A 1 490 ? 7.317 139.323 118.537 1.00 55.15 ? 490 LYS A CB 1 ATOM 3782 C CG . LYS A 1 490 ? 8.212 139.644 117.347 1.00 48.07 ? 490 LYS A CG 1 ATOM 3783 C CD . LYS A 1 490 ? 7.488 140.479 116.311 1.00 47.61 ? 490 LYS A CD 1 ATOM 3784 C CE . LYS A 1 490 ? 8.409 140.814 115.156 1.00 55.01 ? 490 LYS A CE 1 ATOM 3785 N NZ . LYS A 1 490 ? 7.724 141.621 114.115 1.00 58.91 ? 490 LYS A NZ 1 ATOM 3786 N N . ARG A 1 491 ? 8.321 139.550 121.765 1.00 59.84 ? 491 ARG A N 1 ATOM 3787 C CA . ARG A 1 491 ? 9.034 140.263 122.823 1.00 59.80 ? 491 ARG A CA 1 ATOM 3788 C C . ARG A 1 491 ? 10.066 139.355 123.493 1.00 61.86 ? 491 ARG A C 1 ATOM 3789 O O . ARG A 1 491 ? 11.069 139.833 124.024 1.00 65.30 ? 491 ARG A O 1 ATOM 3790 C CB . ARG A 1 491 ? 8.038 140.800 123.851 1.00 59.47 ? 491 ARG A CB 1 ATOM 3791 C CG . ARG A 1 491 ? 8.659 141.613 124.984 1.00 69.98 ? 491 ARG A CG 1 ATOM 3792 C CD . ARG A 1 491 ? 7.597 142.061 125.978 1.00 62.16 ? 491 ARG A CD 1 ATOM 3793 N NE . ARG A 1 491 ? 6.986 140.925 126.667 1.00 62.09 ? 491 ARG A NE 1 ATOM 3794 C CZ . ARG A 1 491 ? 5.826 140.973 127.317 1.00 61.72 ? 491 ARG A CZ 1 ATOM 3795 N NH1 . ARG A 1 491 ? 5.131 142.102 127.366 1.00 63.93 ? 491 ARG A NH1 1 ATOM 3796 N NH2 . ARG A 1 491 ? 5.354 139.886 127.911 1.00 60.33 ? 491 ARG A NH2 1 ATOM 3797 N N . ASN A 1 492 ? 9.812 138.049 123.463 1.00 62.67 ? 492 ASN A N 1 ATOM 3798 C CA . ASN A 1 492 ? 10.735 137.061 124.016 1.00 63.30 ? 492 ASN A CA 1 ATOM 3799 C C . ASN A 1 492 ? 11.777 136.546 123.021 1.00 69.35 ? 492 ASN A C 1 ATOM 3800 O O . ASN A 1 492 ? 12.895 136.217 123.413 1.00 77.98 ? 492 ASN A O 1 ATOM 3801 C CB . ASN A 1 492 ? 9.951 135.885 124.617 1.00 65.13 ? 492 ASN A CB 1 ATOM 3802 C CG . ASN A 1 492 ? 9.402 136.186 126.008 1.00 72.92 ? 492 ASN A CG 1 ATOM 3803 O OD1 . ASN A 1 492 ? 10.052 136.864 126.807 1.00 77.01 ? 492 ASN A OD1 1 ATOM 3804 N ND2 . ASN A 1 492 ? 8.187 135.694 126.297 1.00 76.81 ? 492 ASN A ND2 1 ATOM 3805 N N . TRP A 1 493 ? 11.412 136.488 121.740 1.00 64.57 ? 493 TRP A N 1 ATOM 3806 C CA . TRP A 1 493 ? 12.251 135.846 120.721 1.00 67.63 ? 493 TRP A CA 1 ATOM 3807 C C . TRP A 1 493 ? 12.478 136.722 119.488 1.00 68.37 ? 493 TRP A C 1 ATOM 3808 O O . TRP A 1 493 ? 11.879 137.789 119.359 1.00 65.75 ? 493 TRP A O 1 ATOM 3809 C CB . TRP A 1 493 ? 11.634 134.509 120.294 1.00 70.30 ? 493 TRP A CB 1 ATOM 3810 C CG . TRP A 1 493 ? 11.255 133.609 121.437 1.00 72.53 ? 493 TRP A CG 1 ATOM 3811 C CD1 . TRP A 1 493 ? 10.075 133.610 122.123 1.00 71.14 ? 493 TRP A CD1 1 ATOM 3812 C CD2 . TRP A 1 493 ? 12.057 132.576 122.022 1.00 77.64 ? 493 TRP A CD2 1 ATOM 3813 N NE1 . TRP A 1 493 ? 10.093 132.648 123.104 1.00 75.97 ? 493 TRP A NE1 1 ATOM 3814 C CE2 . TRP A 1 493 ? 11.297 131.996 123.062 1.00 76.10 ? 493 TRP A CE2 1 ATOM 3815 C CE3 . TRP A 1 493 ? 13.345 132.084 121.769 1.00 78.32 ? 493 TRP A CE3 1 ATOM 3816 C CZ2 . TRP A 1 493 ? 11.781 130.948 123.850 1.00 77.82 ? 493 TRP A CZ2 1 ATOM 3817 C CZ3 . TRP A 1 493 ? 13.825 131.042 122.553 1.00 83.04 ? 493 TRP A CZ3 1 ATOM 3818 C CH2 . TRP A 1 493 ? 13.043 130.486 123.581 1.00 84.63 ? 493 TRP A CH2 1 ATOM 3819 N N . THR A 1 494 ? 13.350 136.259 118.591 1.00 70.52 ? 494 THR A N 1 ATOM 3820 C CA . THR A 1 494 ? 13.622 136.938 117.314 1.00 78.95 ? 494 THR A CA 1 ATOM 3821 C C . THR A 1 494 ? 14.119 135.975 116.221 1.00 82.57 ? 494 THR A C 1 ATOM 3822 O O . THR A 1 494 ? 14.891 135.054 116.495 1.00 85.40 ? 494 THR A O 1 ATOM 3823 C CB . THR A 1 494 ? 14.596 138.145 117.476 1.00 72.60 ? 494 THR A CB 1 ATOM 3824 O OG1 . THR A 1 494 ? 14.958 138.651 116.186 1.00 76.34 ? 494 THR A OG1 1 ATOM 3825 C CG2 . THR A 1 494 ? 15.859 137.751 118.231 1.00 81.09 ? 494 THR A CG2 1 ATOM 3826 N N . ILE A 1 495 ? 13.671 136.209 114.987 1.00 81.90 ? 495 ILE A N 1 ATOM 3827 C CA . ILE A 1 495 ? 13.982 135.341 113.847 1.00 80.26 ? 495 ILE A CA 1 ATOM 3828 C C . ILE A 1 495 ? 14.875 136.039 112.812 1.00 90.14 ? 495 ILE A C 1 ATOM 3829 O O . ILE A 1 495 ? 14.659 137.206 112.482 1.00 92.32 ? 495 ILE A O 1 ATOM 3830 C CB . ILE A 1 495 ? 12.677 134.800 113.176 1.00 84.37 ? 495 ILE A CB 1 ATOM 3831 C CG1 . ILE A 1 495 ? 12.958 133.591 112.279 1.00 83.58 ? 495 ILE A CG1 1 ATOM 3832 C CG2 . ILE A 1 495 ? 11.916 135.901 112.422 1.00 87.30 ? 495 ILE A CG2 1 ATOM 3833 C CD1 . ILE A 1 495 ? 12.910 132.268 113.008 1.00 78.60 ? 495 ILE A CD1 1 ATOM 3834 N N . ASN A 1 496 ? 15.875 135.317 112.306 1.00 98.11 ? 496 ASN A N 1 ATOM 3835 C CA . ASN A 1 496 ? 16.821 135.863 111.323 1.00 102.27 ? 496 ASN A CA 1 ATOM 3836 C C . ASN A 1 496 ? 17.037 134.933 110.122 1.00 106.79 ? 496 ASN A C 1 ATOM 3837 O O . ASN A 1 496 ? 17.271 133.733 110.295 1.00 103.40 ? 496 ASN A O 1 ATOM 3838 C CB . ASN A 1 496 ? 18.171 136.171 111.988 1.00 104.11 ? 496 ASN A CB 1 ATOM 3839 C CG . ASN A 1 496 ? 18.048 137.127 113.169 1.00 102.96 ? 496 ASN A CG 1 ATOM 3840 O OD1 . ASN A 1 496 ? 17.959 138.342 112.992 1.00 97.84 ? 496 ASN A OD1 1 ATOM 3841 N ND2 . ASN A 1 496 ? 18.061 136.577 114.381 1.00 92.29 ? 496 ASN A ND2 1 ATOM 3842 N N . ARG A 1 497 ? 16.959 135.494 108.913 1.00 108.82 ? 497 ARG A N 1 ATOM 3843 C CA . ARG A 1 497 ? 17.208 134.746 107.671 1.00 110.24 ? 497 ARG A CA 1 ATOM 3844 C C . ARG A 1 497 ? 18.699 134.456 107.464 1.00 117.06 ? 497 ARG A C 1 ATOM 3845 O O . ARG A 1 497 ? 19.543 135.337 107.662 1.00 118.96 ? 497 ARG A O 1 ATOM 3846 C CB . ARG A 1 497 ? 16.621 135.487 106.455 1.00 107.82 ? 497 ARG A CB 1 ATOM 3847 C CG . ARG A 1 497 ? 17.416 135.332 105.149 1.00 103.90 ? 497 ARG A CG 1 ATOM 3848 C CD . ARG A 1 497 ? 16.631 135.771 103.924 1.00 104.66 ? 497 ARG A CD 1 ATOM 3849 N NE . ARG A 1 497 ? 15.904 134.658 103.314 1.00 113.13 ? 497 ARG A NE 1 ATOM 3850 C CZ . ARG A 1 497 ? 15.278 134.710 102.139 1.00 112.59 ? 497 ARG A CZ 1 ATOM 3851 N NH1 . ARG A 1 497 ? 15.280 135.827 101.421 1.00 107.77 ? 497 ARG A NH1 1 ATOM 3852 N NH2 . ARG A 1 497 ? 14.647 133.638 101.676 1.00 106.24 ? 497 ARG A NH2 1 ATOM 3853 N N . LEU A 1 498 ? 19.012 133.227 107.068 1.00 121.06 ? 498 LEU A N 1 ATOM 3854 C CA . LEU A 1 498 ? 20.394 132.825 106.835 1.00 118.78 ? 498 LEU A CA 1 ATOM 3855 C C . LEU A 1 498 ? 20.675 132.860 105.336 1.00 117.71 ? 498 LEU A C 1 ATOM 3856 O O . LEU A 1 498 ? 21.546 133.598 104.875 1.00 115.61 ? 498 LEU A O 1 ATOM 3857 C CB . LEU A 1 498 ? 20.663 131.450 107.448 1.00 111.84 ? 498 LEU A CB 1 ATOM 3858 C CG . LEU A 1 498 ? 21.398 131.439 108.790 1.00 102.01 ? 498 LEU A CG 1 ATOM 3859 C CD1 . LEU A 1 498 ? 20.490 131.935 109.905 1.00 102.32 ? 498 LEU A CD1 1 ATOM 3860 C CD2 . LEU A 1 498 ? 21.925 130.046 109.103 1.00 97.63 ? 498 LEU A CD2 1 ATOM 3861 N N . ASN A 1 499 ? 19.933 132.057 104.581 1.00 118.41 ? 499 ASN A N 1 ATOM 3862 C CA . ASN A 1 499 ? 20.101 131.994 103.134 1.00 118.16 ? 499 ASN A CA 1 ATOM 3863 C C . ASN A 1 499 ? 18.781 131.977 102.370 1.00 117.24 ? 499 ASN A C 1 ATOM 3864 O O . ASN A 1 499 ? 18.473 132.907 101.624 1.00 119.18 ? 499 ASN A O 1 ATOM 3865 C CB . ASN A 1 499 ? 20.923 130.750 102.792 1.00 117.11 ? 499 ASN A CB 1 ATOM 3866 C CG . ASN A 1 499 ? 20.755 129.642 103.813 1.00 114.22 ? 499 ASN A CG 1 ATOM 3867 O OD1 . ASN A 1 499 ? 21.600 128.754 103.927 1.00 107.25 ? 499 ASN A OD1 1 ATOM 3868 N ND2 . ASN A 1 499 ? 19.661 129.689 104.563 1.00 115.25 ? 499 ASN A ND2 1 ATOM 3869 N N . GLY A 1 500 ? 17.998 130.928 102.582 1.00 117.98 ? 500 GLY A N 1 ATOM 3870 C CA . GLY A 1 500 ? 16.656 130.823 102.040 1.00 111.14 ? 500 GLY A CA 1 ATOM 3871 C C . GLY A 1 500 ? 15.941 129.841 102.936 1.00 112.49 ? 500 GLY A C 1 ATOM 3872 O O . GLY A 1 500 ? 15.269 130.220 103.896 1.00 118.60 ? 500 GLY A O 1 ATOM 3873 N N . ASP A 1 501 ? 16.113 128.563 102.626 1.00 107.51 ? 501 ASP A N 1 ATOM 3874 C CA . ASP A 1 501 ? 15.837 127.493 103.569 1.00 115.95 ? 501 ASP A CA 1 ATOM 3875 C C . ASP A 1 501 ? 16.329 127.166 104.970 1.00 115.46 ? 501 ASP A C 1 ATOM 3876 O O . ASP A 1 501 ? 15.971 126.142 105.553 1.00 110.60 ? 501 ASP A O 1 ATOM 3877 C CB . ASP A 1 501 ? 16.346 126.457 102.568 1.00 115.79 ? 501 ASP A CB 1 ATOM 3878 C CG . ASP A 1 501 ? 17.856 126.321 102.588 1.00 126.76 ? 501 ASP A CG 1 ATOM 3879 O OD1 . ASP A 1 501 ? 18.398 125.567 101.752 1.00 121.36 ? 501 ASP A OD1 1 ATOM 3880 O OD2 . ASP A 1 501 ? 18.501 126.968 103.440 1.00 131.51 ? 501 ASP A OD2 1 ATOM 3881 N N . PHE A 1 502 ? 17.159 128.060 105.499 1.00 114.54 ? 502 PHE A N 1 ATOM 3882 C CA . PHE A 1 502 ? 17.712 127.925 106.840 1.00 114.28 ? 502 PHE A CA 1 ATOM 3883 C C . PHE A 1 502 ? 17.650 129.258 107.582 1.00 111.15 ? 502 PHE A C 1 ATOM 3884 O O . PHE A 1 502 ? 18.092 130.288 107.073 1.00 111.11 ? 502 PHE A O 1 ATOM 3885 C CB . PHE A 1 502 ? 19.156 127.424 106.777 1.00 117.94 ? 502 PHE A CB 1 ATOM 3886 C CG . PHE A 1 502 ? 19.277 125.965 106.438 1.00 122.79 ? 502 PHE A CG 1 ATOM 3887 C CD1 . PHE A 1 502 ? 19.237 125.003 107.433 1.00 115.42 ? 502 PHE A CD1 1 ATOM 3888 C CD2 . PHE A 1 502 ? 19.431 125.556 105.124 1.00 131.62 ? 502 PHE A CD2 1 ATOM 3889 C CE1 . PHE A 1 502 ? 19.348 123.661 107.124 1.00 115.82 ? 502 PHE A CE1 1 ATOM 3890 C CE2 . PHE A 1 502 ? 19.542 124.215 104.809 1.00 129.18 ? 502 PHE A CE2 1 ATOM 3891 C CZ . PHE A 1 502 ? 19.501 123.267 105.810 1.00 122.23 ? 502 PHE A CZ 1 ATOM 3892 N N . ALA A 1 503 ? 17.093 129.224 108.787 1.00 104.47 ? 503 ALA A N 1 ATOM 3893 C CA . ALA A 1 503 ? 16.926 130.419 109.621 1.00 106.77 ? 503 ALA A CA 1 ATOM 3894 C C . ALA A 1 503 ? 17.262 130.162 111.092 1.00 103.39 ? 503 ALA A C 1 ATOM 3895 O O . ALA A 1 503 ? 17.163 129.028 111.569 1.00 94.81 ? 503 ALA A O 1 ATOM 3896 C CB . ALA A 1 503 ? 15.508 130.967 109.486 1.00 105.29 ? 503 ALA A CB 1 ATOM 3897 N N . GLN A 1 504 ? 17.649 131.222 111.804 1.00 104.19 ? 504 GLN A N 1 ATOM 3898 C CA . GLN A 1 504 ? 18.026 131.116 113.216 1.00 100.50 ? 504 GLN A CA 1 ATOM 3899 C C . GLN A 1 504 ? 17.031 131.773 114.173 1.00 92.34 ? 504 GLN A C 1 ATOM 3900 O O . GLN A 1 504 ? 16.387 132.772 113.838 1.00 86.64 ? 504 GLN A O 1 ATOM 3901 C CB . GLN A 1 504 ? 19.437 131.667 113.464 1.00 104.33 ? 504 GLN A CB 1 ATOM 3902 C CG . GLN A 1 504 ? 19.583 133.175 113.281 1.00 103.00 ? 504 GLN A CG 1 ATOM 3903 C CD . GLN A 1 504 ? 20.697 133.780 114.122 1.00 111.52 ? 504 GLN A CD 1 ATOM 3904 O OE1 . GLN A 1 504 ? 20.514 134.826 114.745 1.00 110.06 ? 504 GLN A OE1 1 ATOM 3905 N NE2 . GLN A 1 504 ? 21.857 133.127 114.143 1.00 116.59 ? 504 GLN A NE2 1 ATOM 3906 N N . LEU A 1 505 ? 16.929 131.197 115.367 1.00 93.80 ? 505 LEU A N 1 ATOM 3907 C CA . LEU A 1 505 ? 16.082 131.717 116.432 1.00 88.07 ? 505 LEU A CA 1 ATOM 3908 C C . LEU A 1 505 ? 16.876 131.812 117.730 1.00 90.99 ? 505 LEU A C 1 ATOM 3909 O O . LEU A 1 505 ? 17.670 130.923 118.051 1.00 96.42 ? 505 LEU A O 1 ATOM 3910 C CB . LEU A 1 505 ? 14.856 130.818 116.629 1.00 84.05 ? 505 LEU A CB 1 ATOM 3911 C CG . LEU A 1 505 ? 13.862 131.146 117.750 1.00 75.77 ? 505 LEU A CG 1 ATOM 3912 C CD1 . LEU A 1 505 ? 13.012 132.364 117.410 1.00 79.09 ? 505 LEU A CD1 1 ATOM 3913 C CD2 . LEU A 1 505 ? 12.979 129.946 118.038 1.00 75.19 ? 505 LEU A CD2 1 ATOM 3914 N N . ASN A 1 506 ? 16.656 132.899 118.466 1.00 91.56 ? 506 ASN A N 1 ATOM 3915 C CA . ASN A 1 506 ? 17.298 133.120 119.761 1.00 97.76 ? 506 ASN A CA 1 ATOM 3916 C C . ASN A 1 506 ? 16.497 134.072 120.643 1.00 95.32 ? 506 ASN A C 1 ATOM 3917 O O . ASN A 1 506 ? 15.895 135.030 120.152 1.00 89.87 ? 506 ASN A O 1 ATOM 3918 C CB . ASN A 1 506 ? 18.737 133.625 119.583 1.00 99.01 ? 506 ASN A CB 1 ATOM 3919 C CG . ASN A 1 506 ? 18.852 134.699 118.520 1.00 94.16 ? 506 ASN A CG 1 ATOM 3920 O OD1 . ASN A 1 506 ? 19.111 134.405 117.353 1.00 92.65 ? 506 ASN A OD1 1 ATOM 3921 N ND2 . ASN A 1 506 ? 18.645 135.949 118.915 1.00 97.41 ? 506 ASN A ND2 1 ATOM 3922 N N . LEU A 1 507 ? 16.490 133.791 121.945 1.00 99.19 ? 507 LEU A N 1 ATOM 3923 C CA . LEU A 1 507 ? 15.805 134.629 122.931 1.00 96.80 ? 507 LEU A CA 1 ATOM 3924 C C . LEU A 1 507 ? 16.575 135.920 123.192 1.00 101.24 ? 507 LEU A C 1 ATOM 3925 O O . LEU A 1 507 ? 17.800 135.900 123.337 1.00 108.62 ? 507 LEU A O 1 ATOM 3926 C CB . LEU A 1 507 ? 15.549 133.856 124.239 1.00 95.38 ? 507 LEU A CB 1 ATOM 3927 C CG . LEU A 1 507 ? 16.620 133.174 125.121 1.00 106.67 ? 507 LEU A CG 1 ATOM 3928 C CD1 . LEU A 1 507 ? 17.682 132.390 124.329 1.00 110.66 ? 507 LEU A CD1 1 ATOM 3929 C CD2 . LEU A 1 507 ? 17.286 134.136 126.105 1.00 118.41 ? 507 LEU A CD2 1 ATOM 3930 N N . LYS A 1 508 ? 15.855 137.040 123.239 1.00 100.56 ? 508 LYS A N 1 ATOM 3931 C CA . LYS A 1 508 ? 16.492 138.341 123.435 1.00 106.16 ? 508 LYS A CA 1 ATOM 3932 C C . LYS A 1 508 ? 16.239 138.942 124.824 1.00 103.75 ? 508 LYS A C 1 ATOM 3933 O O . LYS A 1 508 ? 16.650 140.071 125.106 1.00 104.42 ? 508 LYS A O 1 ATOM 3934 C CB . LYS A 1 508 ? 16.104 139.321 122.320 1.00 111.72 ? 508 LYS A CB 1 ATOM 3935 C CG . LYS A 1 508 ? 17.229 140.288 121.951 1.00 121.11 ? 508 LYS A CG 1 ATOM 3936 C CD . LYS A 1 508 ? 16.773 141.347 120.952 1.00 122.31 ? 508 LYS A CD 1 ATOM 3937 C CE . LYS A 1 508 ? 17.922 142.287 120.581 1.00 109.53 ? 508 LYS A CE 1 ATOM 3938 N NZ . LYS A 1 508 ? 18.408 143.098 121.753 1.00 101.19 ? 508 LYS A NZ 1 ATOM 3939 N N . ILE A 1 509 ? 15.569 138.184 125.690 1.00 99.41 ? 509 ILE A N 1 ATOM 3940 C CA . ILE A 1 509 ? 15.505 138.534 127.109 1.00 102.79 ? 509 ILE A CA 1 ATOM 3941 C C . ILE A 1 509 ? 16.840 138.174 127.764 1.00 116.30 ? 509 ILE A C 1 ATOM 3942 O O . ILE A 1 509 ? 17.601 137.356 127.232 1.00 118.48 ? 509 ILE A O 1 ATOM 3943 C CB . ILE A 1 509 ? 14.334 137.834 127.850 1.00 99.39 ? 509 ILE A CB 1 ATOM 3944 C CG1 . ILE A 1 509 ? 14.502 136.304 127.858 1.00 102.70 ? 509 ILE A CG1 1 ATOM 3945 C CG2 . ILE A 1 509 ? 12.995 138.267 127.270 1.00 84.35 ? 509 ILE A CG2 1 ATOM 3946 C CD1 . ILE A 1 509 ? 13.861 135.608 129.053 1.00 96.14 ? 509 ILE A CD1 1 ATOM 3947 N N . LYS A 1 510 ? 17.129 138.784 128.910 1.00 115.64 ? 510 LYS A N 1 ATOM 3948 C CA . LYS A 1 510 ? 18.366 138.477 129.627 1.00 124.14 ? 510 LYS A CA 1 ATOM 3949 C C . LYS A 1 510 ? 18.276 137.172 130.426 1.00 126.23 ? 510 LYS A C 1 ATOM 3950 O O . LYS A 1 510 ? 19.222 136.378 130.428 1.00 130.35 ? 510 LYS A O 1 ATOM 3951 C CB . LYS A 1 510 ? 18.803 139.649 130.514 1.00 130.02 ? 510 LYS A CB 1 ATOM 3952 C CG . LYS A 1 510 ? 19.408 140.818 129.734 1.00 128.01 ? 510 LYS A CG 1 ATOM 3953 C CD . LYS A 1 510 ? 20.560 141.472 130.492 1.00 133.89 ? 510 LYS A CD 1 ATOM 3954 C CE . LYS A 1 510 ? 21.848 140.654 130.379 1.00 129.83 ? 510 LYS A CE 1 ATOM 3955 N NZ . LYS A 1 510 ? 22.954 141.229 131.197 1.00 117.29 ? 510 LYS A NZ 1 ATOM 3956 N N . PHE A 1 511 ? 17.132 136.950 131.079 1.00 120.93 ? 511 PHE A N 1 ATOM 3957 C CA . PHE A 1 511 ? 16.897 135.754 131.899 1.00 115.54 ? 511 PHE A CA 1 ATOM 3958 C C . PHE A 1 511 ? 17.093 134.444 131.130 1.00 113.62 ? 511 PHE A C 1 ATOM 3959 O O . PHE A 1 511 ? 16.944 134.391 129.908 1.00 112.87 ? 511 PHE A O 1 ATOM 3960 C CB . PHE A 1 511 ? 15.502 135.803 132.519 1.00 106.40 ? 511 PHE A CB 1 ATOM 3961 N N . GLU A 1 513 ? 12.993 130.287 132.881 1.00 107.19 ? 513 GLU A N 1 ATOM 3962 C CA . GLU A 1 513 ? 13.378 129.240 133.824 1.00 111.45 ? 513 GLU A CA 1 ATOM 3963 C C . GLU A 1 513 ? 13.063 127.848 133.275 1.00 117.29 ? 513 GLU A C 1 ATOM 3964 O O . GLU A 1 513 ? 12.842 127.686 132.072 1.00 119.53 ? 513 GLU A O 1 ATOM 3965 C CB . GLU A 1 513 ? 12.694 129.456 135.178 1.00 114.51 ? 513 GLU A CB 1 ATOM 3966 C CG . GLU A 1 513 ? 13.271 130.608 135.998 1.00 119.23 ? 513 GLU A CG 1 ATOM 3967 C CD . GLU A 1 513 ? 12.594 130.778 137.353 1.00 114.80 ? 513 GLU A CD 1 ATOM 3968 O OE1 . GLU A 1 513 ? 12.257 129.758 137.996 1.00 112.29 ? 513 GLU A OE1 1 ATOM 3969 O OE2 . GLU A 1 513 ? 12.407 131.938 137.780 1.00 105.39 ? 513 GLU A OE2 1 ATOM 3970 N N . ALA A 1 514 ? 13.054 126.853 134.162 1.00 120.52 ? 514 ALA A N 1 ATOM 3971 C CA . ALA A 1 514 ? 12.786 125.460 133.793 1.00 124.48 ? 514 ALA A CA 1 ATOM 3972 C C . ALA A 1 514 ? 11.323 125.223 133.400 1.00 120.88 ? 514 ALA A C 1 ATOM 3973 O O . ALA A 1 514 ? 10.406 125.699 134.077 1.00 116.73 ? 514 ALA A O 1 ATOM 3974 C CB . ALA A 1 514 ? 13.197 124.522 134.928 1.00 124.36 ? 514 ALA A CB 1 ATOM 3975 N N . GLY A 1 515 ? 11.116 124.492 132.305 1.00 117.88 ? 515 GLY A N 1 ATOM 3976 C CA . GLY A 1 515 ? 9.768 124.152 131.840 1.00 117.70 ? 515 GLY A CA 1 ATOM 3977 C C . GLY A 1 515 ? 9.628 124.032 130.331 1.00 119.56 ? 515 GLY A C 1 ATOM 3978 O O . GLY A 1 515 ? 10.612 123.805 129.620 1.00 120.24 ? 515 GLY A O 1 ATOM 3979 N N . ILE A 1 516 ? 8.393 124.181 129.848 1.00 117.11 ? 516 ILE A N 1 ATOM 3980 C CA . ILE A 1 516 ? 8.085 124.098 128.415 1.00 112.37 ? 516 ILE A CA 1 ATOM 3981 C C . ILE A 1 516 ? 7.655 125.461 127.865 1.00 109.49 ? 516 ILE A C 1 ATOM 3982 O O . ILE A 1 516 ? 6.779 126.123 128.431 1.00 105.02 ? 516 ILE A O 1 ATOM 3983 C CB . ILE A 1 516 ? 6.956 123.073 128.110 1.00 114.23 ? 516 ILE A CB 1 ATOM 3984 C CG1 . ILE A 1 516 ? 6.942 121.929 129.136 1.00 115.57 ? 516 ILE A CG1 1 ATOM 3985 C CG2 . ILE A 1 516 ? 7.080 122.556 126.668 1.00 111.39 ? 516 ILE A CG2 1 ATOM 3986 C CD1 . ILE A 1 516 ? 5.574 121.273 129.324 1.00 104.59 ? 516 ILE A CD1 1 ATOM 3987 N N . TYR A 1 517 ? 8.277 125.867 126.762 1.00 106.76 ? 517 TYR A N 1 ATOM 3988 C CA . TYR A 1 517 ? 7.932 127.107 126.071 1.00 98.91 ? 517 TYR A CA 1 ATOM 3989 C C . TYR A 1 517 ? 7.518 126.780 124.637 1.00 93.76 ? 517 TYR A C 1 ATOM 3990 O O . TYR A 1 517 ? 8.362 126.415 123.815 1.00 94.25 ? 517 TYR A O 1 ATOM 3991 C CB . TYR A 1 517 ? 9.131 128.067 126.046 1.00 100.23 ? 517 TYR A CB 1 ATOM 3992 C CG . TYR A 1 517 ? 9.591 128.595 127.394 1.00 100.69 ? 517 TYR A CG 1 ATOM 3993 C CD1 . TYR A 1 517 ? 10.403 127.825 128.231 1.00 104.64 ? 517 TYR A CD1 1 ATOM 3994 C CD2 . TYR A 1 517 ? 9.243 129.878 127.815 1.00 93.14 ? 517 TYR A CD2 1 ATOM 3995 C CE1 . TYR A 1 517 ? 10.835 128.312 129.461 1.00 106.66 ? 517 TYR A CE1 1 ATOM 3996 C CE2 . TYR A 1 517 ? 9.672 130.374 129.043 1.00 91.25 ? 517 TYR A CE2 1 ATOM 3997 C CZ . TYR A 1 517 ? 10.466 129.587 129.859 1.00 103.18 ? 517 TYR A CZ 1 ATOM 3998 O OH . TYR A 1 517 ? 10.892 130.074 131.074 1.00 117.01 ? 517 TYR A OH 1 ATOM 3999 N N . GLU A 1 518 ? 6.228 126.895 124.333 1.00 87.40 ? 518 GLU A N 1 ATOM 4000 C CA . GLU A 1 518 ? 5.765 126.649 122.965 1.00 81.17 ? 518 GLU A CA 1 ATOM 4001 C C . GLU A 1 518 ? 5.824 127.920 122.110 1.00 73.70 ? 518 GLU A C 1 ATOM 4002 O O . GLU A 1 518 ? 5.154 128.914 122.404 1.00 76.10 ? 518 GLU A O 1 ATOM 4003 C CB . GLU A 1 518 ? 4.381 125.977 122.934 1.00 84.77 ? 518 GLU A CB 1 ATOM 4004 C CG . GLU A 1 518 ? 3.258 126.720 123.653 1.00 95.41 ? 518 GLU A CG 1 ATOM 4005 C CD . GLU A 1 518 ? 1.879 126.207 123.268 1.00 95.63 ? 518 GLU A CD 1 ATOM 4006 O OE1 . GLU A 1 518 ? 1.012 127.038 122.925 1.00 86.98 ? 518 GLU A OE1 1 ATOM 4007 O OE2 . GLU A 1 518 ? 1.661 124.975 123.300 1.00 85.24 ? 518 GLU A OE2 1 ATOM 4008 N N . VAL A 1 519 ? 6.648 127.877 121.065 1.00 62.08 ? 519 VAL A N 1 ATOM 4009 C CA . VAL A 1 519 ? 6.917 129.046 120.227 1.00 61.02 ? 519 VAL A CA 1 ATOM 4010 C C . VAL A 1 519 ? 6.336 128.866 118.823 1.00 60.63 ? 519 VAL A C 1 ATOM 4011 O O . VAL A 1 519 ? 6.790 128.000 118.074 1.00 63.47 ? 519 VAL A O 1 ATOM 4012 C CB . VAL A 1 519 ? 8.436 129.342 120.128 1.00 60.35 ? 519 VAL A CB 1 ATOM 4013 C CG1 . VAL A 1 519 ? 8.692 130.580 119.277 1.00 60.85 ? 519 VAL A CG1 1 ATOM 4014 C CG2 . VAL A 1 519 ? 9.045 129.514 121.511 1.00 63.69 ? 519 VAL A CG2 1 ATOM 4015 N N . PRO A 1 520 ? 5.326 129.684 118.465 1.00 53.00 ? 520 PRO A N 1 ATOM 4016 C CA . PRO A 1 520 ? 4.697 129.620 117.147 1.00 48.12 ? 520 PRO A CA 1 ATOM 4017 C C . PRO A 1 520 ? 5.551 130.287 116.077 1.00 48.85 ? 520 PRO A C 1 ATOM 4018 O O . PRO A 1 520 ? 6.132 131.344 116.321 1.00 51.20 ? 520 PRO A O 1 ATOM 4019 C CB . PRO A 1 520 ? 3.388 130.402 117.337 1.00 48.88 ? 520 PRO A CB 1 ATOM 4020 C CG . PRO A 1 520 ? 3.309 130.746 118.799 1.00 51.53 ? 520 PRO A CG 1 ATOM 4021 C CD . PRO A 1 520 ? 4.705 130.719 119.306 1.00 52.18 ? 520 PRO A CD 1 ATOM 4022 N N . ILE A 1 521 ? 5.628 129.660 114.904 1.00 53.91 ? 521 ILE A N 1 ATOM 4023 C CA . ILE A 1 521 ? 6.392 130.195 113.773 1.00 53.87 ? 521 ILE A CA 1 ATOM 4024 C C . ILE A 1 521 ? 5.591 130.105 112.475 1.00 53.81 ? 521 ILE A C 1 ATOM 4025 O O . ILE A 1 521 ? 5.065 129.047 112.133 1.00 61.57 ? 521 ILE A O 1 ATOM 4026 C CB . ILE A 1 521 ? 7.756 129.473 113.592 1.00 46.03 ? 521 ILE A CB 1 ATOM 4027 C CG1 . ILE A 1 521 ? 8.623 129.628 114.843 1.00 43.97 ? 521 ILE A CG1 1 ATOM 4028 C CG2 . ILE A 1 521 ? 8.503 130.022 112.378 1.00 52.69 ? 521 ILE A CG2 1 ATOM 4029 C CD1 . ILE A 1 521 ? 9.759 128.643 114.938 1.00 46.61 ? 521 ILE A CD1 1 ATOM 4030 N N . ILE A 1 522 ? 5.503 131.226 111.766 1.00 52.84 ? 522 ILE A N 1 ATOM 4031 C CA . ILE A 1 522 ? 4.872 131.275 110.452 1.00 52.88 ? 522 ILE A CA 1 ATOM 4032 C C . ILE A 1 522 ? 5.916 130.977 109.379 1.00 60.68 ? 522 ILE A C 1 ATOM 4033 O O . ILE A 1 522 ? 6.950 131.646 109.301 1.00 66.78 ? 522 ILE A O 1 ATOM 4034 C CB . ILE A 1 522 ? 4.211 132.647 110.191 1.00 49.77 ? 522 ILE A CB 1 ATOM 4035 C CG1 . ILE A 1 522 ? 3.146 132.930 111.252 1.00 47.85 ? 522 ILE A CG1 1 ATOM 4036 C CG2 . ILE A 1 522 ? 3.603 132.702 108.793 1.00 47.99 ? 522 ILE A CG2 1 ATOM 4037 C CD1 . ILE A 1 522 ? 2.762 134.390 111.371 1.00 47.27 ? 522 ILE A CD1 1 ATOM 4038 N N . ILE A 1 523 ? 5.645 129.957 108.569 1.00 63.49 ? 523 ILE A N 1 ATOM 4039 C CA . ILE A 1 523 ? 6.543 129.552 107.490 1.00 61.80 ? 523 ILE A CA 1 ATOM 4040 C C . ILE A 1 523 ? 5.787 129.504 106.163 1.00 64.87 ? 523 ILE A C 1 ATOM 4041 O O . ILE A 1 523 ? 4.686 128.955 106.089 1.00 63.89 ? 523 ILE A O 1 ATOM 4042 C CB . ILE A 1 523 ? 7.207 128.183 107.776 1.00 61.30 ? 523 ILE A CB 1 ATOM 4043 C CG1 . ILE A 1 523 ? 7.803 128.156 109.187 1.00 59.98 ? 523 ILE A CG1 1 ATOM 4044 C CG2 . ILE A 1 523 ? 8.286 127.881 106.737 1.00 74.78 ? 523 ILE A CG2 1 ATOM 4045 C CD1 . ILE A 1 523 ? 7.996 126.771 109.763 1.00 66.55 ? 523 ILE A CD1 1 ATOM 4046 N N . THR A 1 524 ? 6.386 130.085 105.127 1.00 61.36 ? 524 THR A N 1 ATOM 4047 C CA . THR A 1 524 ? 5.768 130.162 103.806 1.00 62.77 ? 524 THR A CA 1 ATOM 4048 C C . THR A 1 524 ? 6.728 129.641 102.740 1.00 77.48 ? 524 THR A C 1 ATOM 4049 O O . THR A 1 524 ? 7.923 129.937 102.781 1.00 84.26 ? 524 THR A O 1 ATOM 4050 C CB . THR A 1 524 ? 5.366 131.615 103.468 1.00 61.92 ? 524 THR A CB 1 ATOM 4051 O OG1 . THR A 1 524 ? 4.644 132.181 104.567 1.00 59.78 ? 524 THR A OG1 1 ATOM 4052 C CG2 . THR A 1 524 ? 4.496 131.673 102.219 1.00 71.25 ? 524 THR A CG2 1 ATOM 4053 N N . ASP A 1 525 ? 6.205 128.895 101.771 1.00 79.48 ? 525 ASP A N 1 ATOM 4054 C CA . ASP A 1 525 ? 7.026 128.375 100.679 1.00 80.24 ? 525 ASP A CA 1 ATOM 4055 C C . ASP A 1 525 ? 6.694 129.052 99.348 1.00 80.44 ? 525 ASP A C 1 ATOM 4056 O O . ASP A 1 525 ? 5.624 129.641 99.196 1.00 83.06 ? 525 ASP A O 1 ATOM 4057 C CB . ASP A 1 525 ? 6.855 126.860 100.554 1.00 83.21 ? 525 ASP A CB 1 ATOM 4058 C CG . ASP A 1 525 ? 5.411 126.453 100.336 1.00 83.81 ? 525 ASP A CG 1 ATOM 4059 O OD1 . ASP A 1 525 ? 5.103 125.251 100.478 1.00 85.29 ? 525 ASP A OD1 1 ATOM 4060 O OD2 . ASP A 1 525 ? 4.584 127.335 100.024 1.00 78.55 ? 525 ASP A OD2 1 ATOM 4061 N N . SER A 1 526 ? 7.559 128.921 98.350 1.00 83.71 ? 526 SER A N 1 ATOM 4062 C CA . SER A 1 526 ? 7.375 129.621 97.068 1.00 87.75 ? 526 SER A CA 1 ATOM 4063 C C . SER A 1 526 ? 6.047 129.440 96.289 1.00 86.00 ? 526 SER A C 1 ATOM 4064 O O . SER A 1 526 ? 5.276 130.387 96.137 1.00 86.29 ? 526 SER A O 1 ATOM 4065 C CB . SER A 1 526 ? 8.553 129.317 96.135 1.00 91.03 ? 526 SER A CB 1 ATOM 4066 O OG . SER A 1 526 ? 9.791 129.507 96.799 1.00 91.66 ? 526 SER A OG 1 ATOM 4067 N N . GLY A 1 527 ? 5.812 128.229 95.790 1.00 84.74 ? 527 GLY A N 1 ATOM 4068 C CA . GLY A 1 527 ? 4.874 127.928 94.704 1.00 88.96 ? 527 GLY A CA 1 ATOM 4069 C C . GLY A 1 527 ? 3.523 128.606 94.837 1.00 83.59 ? 527 GLY A C 1 ATOM 4070 O O . GLY A 1 527 ? 2.744 128.279 95.733 1.00 79.13 ? 527 GLY A O 1 ATOM 4071 N N . ASN A 1 528 ? 3.248 129.544 93.933 1.00 88.06 ? 528 ASN A N 1 ATOM 4072 C CA . ASN A 1 528 ? 2.014 130.335 93.973 1.00 92.00 ? 528 ASN A CA 1 ATOM 4073 C C . ASN A 1 528 ? 0.762 129.566 93.525 1.00 92.25 ? 528 ASN A C 1 ATOM 4074 O O . ASN A 1 528 ? 0.819 128.803 92.557 1.00 84.48 ? 528 ASN A O 1 ATOM 4075 C CB . ASN A 1 528 ? 2.170 131.654 93.194 1.00 91.18 ? 528 ASN A CB 1 ATOM 4076 C CG . ASN A 1 528 ? 2.625 131.445 91.760 1.00 87.49 ? 528 ASN A CG 1 ATOM 4077 O OD1 . ASN A 1 528 ? 1.830 131.092 90.888 1.00 85.66 ? 528 ASN A OD1 1 ATOM 4078 N ND2 . ASN A 1 528 ? 3.907 131.684 91.506 1.00 78.06 ? 528 ASN A ND2 1 ATOM 4079 N N . PRO A 1 529 ? -0.368 129.751 94.242 1.00 91.85 ? 529 PRO A N 1 ATOM 4080 C CA . PRO A 1 529 ? -0.510 130.578 95.447 1.00 85.50 ? 529 PRO A CA 1 ATOM 4081 C C . PRO A 1 529 ? 0.247 129.969 96.628 1.00 85.45 ? 529 PRO A C 1 ATOM 4082 O O . PRO A 1 529 ? 0.063 128.782 96.919 1.00 80.34 ? 529 PRO A O 1 ATOM 4083 C CB . PRO A 1 529 ? -2.022 130.565 95.714 1.00 93.46 ? 529 PRO A CB 1 ATOM 4084 C CG . PRO A 1 529 ? -2.651 130.051 94.448 1.00 92.26 ? 529 PRO A CG 1 ATOM 4085 C CD . PRO A 1 529 ? -1.646 129.119 93.868 1.00 90.32 ? 529 PRO A CD 1 ATOM 4086 N N . PRO A 1 530 ? 1.099 130.773 97.302 1.00 86.32 ? 530 PRO A N 1 ATOM 4087 C CA . PRO A 1 530 ? 1.971 130.255 98.356 1.00 78.13 ? 530 PRO A CA 1 ATOM 4088 C C . PRO A 1 530 ? 1.195 129.969 99.632 1.00 73.04 ? 530 PRO A C 1 ATOM 4089 O O . PRO A 1 530 ? 0.363 130.779 100.046 1.00 80.24 ? 530 PRO A O 1 ATOM 4090 C CB . PRO A 1 530 ? 2.978 131.394 98.588 1.00 73.01 ? 530 PRO A CB 1 ATOM 4091 C CG . PRO A 1 530 ? 2.693 132.428 97.534 1.00 72.93 ? 530 PRO A CG 1 ATOM 4092 C CD . PRO A 1 530 ? 1.276 132.224 97.126 1.00 80.00 ? 530 PRO A CD 1 ATOM 4093 N N . LYS A 1 531 ? 1.460 128.817 100.239 1.00 68.18 ? 531 LYS A N 1 ATOM 4094 C CA . LYS A 1 531 ? 0.780 128.428 101.470 1.00 73.90 ? 531 LYS A CA 1 ATOM 4095 C C . LYS A 1 531 ? 1.654 128.649 102.701 1.00 70.67 ? 531 LYS A C 1 ATOM 4096 O O . LYS A 1 531 ? 2.844 128.318 102.703 1.00 70.21 ? 531 LYS A O 1 ATOM 4097 C CB . LYS A 1 531 ? 0.308 126.972 101.399 1.00 75.58 ? 531 LYS A CB 1 ATOM 4098 C CG . LYS A 1 531 ? -0.985 126.778 100.622 1.00 74.61 ? 531 LYS A CG 1 ATOM 4099 C CD . LYS A 1 531 ? -1.738 125.554 101.115 1.00 72.15 ? 531 LYS A CD 1 ATOM 4100 C CE . LYS A 1 531 ? -3.164 125.538 100.593 1.00 75.25 ? 531 LYS A CE 1 ATOM 4101 N NZ . LYS A 1 531 ? -3.972 124.478 101.252 1.00 65.48 ? 531 LYS A NZ 1 ATOM 4102 N N . SER A 1 532 ? 1.052 129.224 103.738 1.00 60.54 ? 532 SER A N 1 ATOM 4103 C CA . SER A 1 532 ? 1.731 129.436 105.007 1.00 53.64 ? 532 SER A CA 1 ATOM 4104 C C . SER A 1 532 ? 1.121 128.543 106.075 1.00 57.82 ? 532 SER A C 1 ATOM 4105 O O . SER A 1 532 ? 0.017 128.024 105.901 1.00 63.85 ? 532 SER A O 1 ATOM 4106 C CB . SER A 1 532 ? 1.631 130.898 105.434 1.00 56.55 ? 532 SER A CB 1 ATOM 4107 O OG . SER A 1 532 ? 1.990 131.770 104.381 1.00 63.54 ? 532 SER A OG 1 ATOM 4108 N N . ASN A 1 533 ? 1.849 128.360 107.174 1.00 54.87 ? 533 ASN A N 1 ATOM 4109 C CA . ASN A 1 533 ? 1.355 127.602 108.322 1.00 61.68 ? 533 ASN A CA 1 ATOM 4110 C C . ASN A 1 533 ? 2.062 128.031 109.603 1.00 60.48 ? 533 ASN A C 1 ATOM 4111 O O . ASN A 1 533 ? 3.241 128.392 109.580 1.00 63.76 ? 533 ASN A O 1 ATOM 4112 C CB . ASN A 1 533 ? 1.542 126.096 108.101 1.00 68.62 ? 533 ASN A CB 1 ATOM 4113 C CG . ASN A 1 533 ? 0.506 125.257 108.839 1.00 67.63 ? 533 ASN A CG 1 ATOM 4114 O OD1 . ASN A 1 533 ? -0.700 125.416 108.640 1.00 62.62 ? 533 ASN A OD1 1 ATOM 4115 N ND2 . ASN A 1 533 ? 0.977 124.345 109.681 1.00 62.70 ? 533 ASN A ND2 1 ATOM 4116 N N . ILE A 1 534 ? 1.335 127.988 110.715 1.00 53.73 ? 534 ILE A N 1 ATOM 4117 C CA . ILE A 1 534 ? 1.899 128.325 112.017 1.00 54.75 ? 534 ILE A CA 1 ATOM 4118 C C . ILE A 1 534 ? 2.258 127.040 112.766 1.00 55.92 ? 534 ILE A C 1 ATOM 4119 O O . ILE A 1 534 ? 1.521 126.589 113.645 1.00 59.61 ? 534 ILE A O 1 ATOM 4120 C CB . ILE A 1 534 ? 0.937 129.208 112.856 1.00 54.39 ? 534 ILE A CB 1 ATOM 4121 C CG1 . ILE A 1 534 ? 0.292 130.289 111.982 1.00 52.69 ? 534 ILE A CG1 1 ATOM 4122 C CG2 . ILE A 1 534 ? 1.674 129.844 114.031 1.00 47.61 ? 534 ILE A CG2 1 ATOM 4123 C CD1 . ILE A 1 534 ? -1.042 130.777 112.493 1.00 42.39 ? 534 ILE A CD1 1 ATOM 4124 N N . SER A 1 535 ? 3.387 126.443 112.394 1.00 53.87 ? 535 SER A N 1 ATOM 4125 C CA . SER A 1 535 ? 3.871 125.240 113.060 1.00 62.93 ? 535 SER A CA 1 ATOM 4126 C C . SER A 1 535 ? 4.523 125.620 114.381 1.00 62.32 ? 535 SER A C 1 ATOM 4127 O O . SER A 1 535 ? 5.403 126.481 114.422 1.00 64.68 ? 535 SER A O 1 ATOM 4128 C CB . SER A 1 535 ? 4.857 124.479 112.171 1.00 72.78 ? 535 SER A CB 1 ATOM 4129 O OG . SER A 1 535 ? 6.059 125.208 111.990 1.00 71.97 ? 535 SER A OG 1 ATOM 4130 N N . ILE A 1 536 ? 4.081 124.977 115.457 1.00 60.33 ? 536 ILE A N 1 ATOM 4131 C CA . ILE A 1 536 ? 4.550 125.297 116.803 1.00 57.46 ? 536 ILE A CA 1 ATOM 4132 C C . ILE A 1 536 ? 5.848 124.556 117.121 1.00 54.12 ? 536 ILE A C 1 ATOM 4133 O O . ILE A 1 536 ? 5.967 123.359 116.867 1.00 65.38 ? 536 ILE A O 1 ATOM 4134 C CB . ILE A 1 536 ? 3.467 124.991 117.871 1.00 58.86 ? 536 ILE A CB 1 ATOM 4135 C CG1 . ILE A 1 536 ? 2.138 125.662 117.495 1.00 56.40 ? 536 ILE A CG1 1 ATOM 4136 C CG2 . ILE A 1 536 ? 3.925 125.458 119.249 1.00 66.50 ? 536 ILE A CG2 1 ATOM 4137 C CD1 . ILE A 1 536 ? 0.917 125.103 118.209 1.00 67.46 ? 536 ILE A CD1 1 ATOM 4138 N N . LEU A 1 537 ? 6.819 125.286 117.661 1.00 54.48 ? 537 LEU A N 1 ATOM 4139 C CA . LEU A 1 537 ? 8.083 124.703 118.089 1.00 66.65 ? 537 LEU A CA 1 ATOM 4140 C C . LEU A 1 537 ? 8.050 124.500 119.599 1.00 78.71 ? 537 LEU A C 1 ATOM 4141 O O . LEU A 1 537 ? 7.914 125.465 120.356 1.00 82.05 ? 537 LEU A O 1 ATOM 4142 C CB . LEU A 1 537 ? 9.254 125.619 117.708 1.00 64.58 ? 537 LEU A CB 1 ATOM 4143 C CG . LEU A 1 537 ? 10.657 125.049 117.446 1.00 63.33 ? 537 LEU A CG 1 ATOM 4144 C CD1 . LEU A 1 537 ? 11.610 126.172 117.085 1.00 58.96 ? 537 LEU A CD1 1 ATOM 4145 C CD2 . LEU A 1 537 ? 11.217 124.257 118.617 1.00 83.54 ? 537 LEU A CD2 1 ATOM 4146 N N . ARG A 1 538 ? 8.163 123.246 120.030 1.00 81.03 ? 538 ARG A N 1 ATOM 4147 C CA . ARG A 1 538 ? 8.243 122.925 121.455 1.00 91.04 ? 538 ARG A CA 1 ATOM 4148 C C . ARG A 1 538 ? 9.669 123.176 121.938 1.00 94.42 ? 538 ARG A C 1 ATOM 4149 O O . ARG A 1 538 ? 10.624 122.600 121.410 1.00 98.52 ? 538 ARG A O 1 ATOM 4150 C CB . ARG A 1 538 ? 7.838 121.467 121.732 1.00 102.32 ? 538 ARG A CB 1 ATOM 4151 C CG . ARG A 1 538 ? 6.507 121.005 121.122 1.00 98.06 ? 538 ARG A CG 1 ATOM 4152 C CD . ARG A 1 538 ? 5.295 121.474 121.920 1.00 95.61 ? 538 ARG A CD 1 ATOM 4153 N NE . ARG A 1 538 ? 4.047 120.949 121.361 1.00 96.47 ? 538 ARG A NE 1 ATOM 4154 C CZ . ARG A 1 538 ? 2.857 121.537 121.474 1.00 99.26 ? 538 ARG A CZ 1 ATOM 4155 N NH1 . ARG A 1 538 ? 2.732 122.692 122.120 1.00 101.21 ? 538 ARG A NH1 1 ATOM 4156 N NH2 . ARG A 1 538 ? 1.786 120.974 120.928 1.00 84.62 ? 538 ARG A NH2 1 ATOM 4157 N N . VAL A 1 539 ? 9.809 124.050 122.931 1.00 99.46 ? 539 VAL A N 1 ATOM 4158 C CA . VAL A 1 539 ? 11.120 124.379 123.490 1.00 105.88 ? 539 VAL A CA 1 ATOM 4159 C C . VAL A 1 539 ? 11.144 124.121 124.999 1.00 114.08 ? 539 VAL A C 1 ATOM 4160 O O . VAL A 1 539 ? 10.209 124.484 125.718 1.00 106.88 ? 539 VAL A O 1 ATOM 4161 C CB . VAL A 1 539 ? 11.529 125.852 123.196 1.00 95.41 ? 539 VAL A CB 1 ATOM 4162 C CG1 . VAL A 1 539 ? 13.002 126.084 123.521 1.00 107.69 ? 539 VAL A CG1 1 ATOM 4163 C CG2 . VAL A 1 539 ? 11.251 126.220 121.744 1.00 84.41 ? 539 VAL A CG2 1 ATOM 4164 N N . LYS A 1 540 ? 12.212 123.476 125.462 1.00 125.01 ? 540 LYS A N 1 ATOM 4165 C CA . LYS A 1 540 ? 12.445 123.279 126.890 1.00 128.47 ? 540 LYS A CA 1 ATOM 4166 C C . LYS A 1 540 ? 13.740 123.961 127.315 1.00 128.61 ? 540 LYS A C 1 ATOM 4167 O O . LYS A 1 540 ? 14.833 123.601 126.862 1.00 125.28 ? 540 LYS A O 1 ATOM 4168 C CB . LYS A 1 540 ? 12.461 121.796 127.250 1.00 130.48 ? 540 LYS A CB 1 ATOM 4169 N N . VAL A 1 541 ? 13.592 124.961 128.178 1.00 127.51 ? 541 VAL A N 1 ATOM 4170 C CA . VAL A 1 541 ? 14.705 125.771 128.660 1.00 132.30 ? 541 VAL A CA 1 ATOM 4171 C C . VAL A 1 541 ? 14.886 125.515 130.158 1.00 135.09 ? 541 VAL A C 1 ATOM 4172 O O . VAL A 1 541 ? 13.909 125.246 130.862 1.00 132.74 ? 541 VAL A O 1 ATOM 4173 C CB . VAL A 1 541 ? 14.448 127.281 128.402 1.00 130.90 ? 541 VAL A CB 1 ATOM 4174 C CG1 . VAL A 1 541 ? 15.718 128.077 128.568 1.00 135.42 ? 541 VAL A CG1 1 ATOM 4175 C CG2 . VAL A 1 541 ? 13.884 127.511 127.001 1.00 122.25 ? 541 VAL A CG2 1 ATOM 4176 N N . CYS A 1 542 ? 16.131 125.584 130.636 1.00 139.74 ? 542 CYS A N 1 ATOM 4177 C CA . CYS A 1 542 ? 16.438 125.396 132.061 1.00 137.68 ? 542 CYS A CA 1 ATOM 4178 C C . CYS A 1 542 ? 16.954 126.681 132.703 1.00 129.27 ? 542 CYS A C 1 ATOM 4179 O O . CYS A 1 542 ? 16.406 127.761 132.481 1.00 128.58 ? 542 CYS A O 1 ATOM 4180 C CB . CYS A 1 542 ? 17.469 124.277 132.258 1.00 145.20 ? 542 CYS A CB 1 ATOM 4181 S SG . CYS A 1 542 ? 17.034 122.674 131.517 1.00 142.27 ? 542 CYS A SG 1 HETATM 4182 CA CA . CA B 2 . ? 21.292 7.471 16.632 1.00 26.12 ? 601 CA A CA 1 HETATM 4183 CA CA . CA C 2 . ? 21.132 10.451 14.019 1.00 14.77 ? 602 CA A CA 1 HETATM 4184 CA CA . CA D 2 . ? 16.642 15.343 13.961 1.00 21.33 ? 603 CA A CA 1 HETATM 4185 CA CA . CA E 2 . ? -1.308 50.303 32.252 1.00 14.10 ? 604 CA A CA 1 HETATM 4186 CA CA . CA F 2 . ? -1.720 55.908 35.839 1.00 29.88 ? 605 CA A CA 1 HETATM 4187 CA CA . CA G 2 . ? -3.796 49.596 29.188 1.00 34.15 ? 606 CA A CA 1 HETATM 4188 CA CA . CA H 2 . ? -8.110 85.873 63.833 1.00 59.23 ? 607 CA A CA 1 HETATM 4189 CA CA . CA I 2 . ? -11.947 84.787 65.366 1.00 49.59 ? 608 CA A CA 1 HETATM 4190 CA CA . CA J 2 . ? -13.640 87.672 71.349 1.00 90.84 ? 609 CA A CA 1 HETATM 4191 CA CA . CA K 2 . ? 1.407 118.687 95.770 1.00 68.62 ? 610 CA A CA 1 HETATM 4192 CA CA . CA L 2 . ? -1.704 116.570 97.587 1.00 65.34 ? 611 CA A CA 1 HETATM 4193 CA CA . CA M 2 . ? 4.234 123.291 99.895 1.00 62.21 ? 612 CA A CA 1 HETATM 4194 C C1 . MAN N 3 . ? 4.767 20.075 23.754 1.00 39.17 ? 701 MAN A C1 1 HETATM 4195 C C2 . MAN N 3 . ? 5.001 18.936 24.734 1.00 40.76 ? 701 MAN A C2 1 HETATM 4196 C C3 . MAN N 3 . ? 3.887 17.901 24.571 1.00 45.13 ? 701 MAN A C3 1 HETATM 4197 C C4 . MAN N 3 . ? 2.484 18.508 24.383 1.00 54.04 ? 701 MAN A C4 1 HETATM 4198 C C5 . MAN N 3 . ? 2.445 19.891 23.710 1.00 46.83 ? 701 MAN A C5 1 HETATM 4199 C C6 . MAN N 3 . ? 1.161 20.654 24.028 1.00 48.31 ? 701 MAN A C6 1 HETATM 4200 O O2 . MAN N 3 . ? 5.012 19.457 26.046 1.00 38.89 ? 701 MAN A O2 1 HETATM 4201 O O3 . MAN N 3 . ? 3.883 17.040 25.690 1.00 49.00 ? 701 MAN A O3 1 HETATM 4202 O O4 . MAN N 3 . ? 1.724 17.621 23.590 1.00 61.15 ? 701 MAN A O4 1 HETATM 4203 O O5 . MAN N 3 . ? 3.547 20.686 24.101 1.00 45.69 ? 701 MAN A O5 1 HETATM 4204 O O6 . MAN N 3 . ? 1.163 21.075 25.379 1.00 46.24 ? 701 MAN A O6 1 HETATM 4205 C C1 . MAN O 3 . ? 4.964 24.217 28.762 1.00 40.41 ? 702 MAN A C1 1 HETATM 4206 C C2 . MAN O 3 . ? 4.840 22.847 28.094 1.00 36.05 ? 702 MAN A C2 1 HETATM 4207 C C3 . MAN O 3 . ? 3.371 22.445 28.028 1.00 39.47 ? 702 MAN A C3 1 HETATM 4208 C C4 . MAN O 3 . ? 2.747 22.367 29.423 1.00 44.48 ? 702 MAN A C4 1 HETATM 4209 C C5 . MAN O 3 . ? 3.251 23.427 30.415 1.00 42.85 ? 702 MAN A C5 1 HETATM 4210 C C6 . MAN O 3 . ? 3.916 22.776 31.634 1.00 55.64 ? 702 MAN A C6 1 HETATM 4211 O O2 . MAN O 3 . ? 5.613 21.884 28.784 1.00 40.64 ? 702 MAN A O2 1 HETATM 4212 O O3 . MAN O 3 . ? 3.239 21.211 27.350 1.00 39.31 ? 702 MAN A O3 1 HETATM 4213 O O4 . MAN O 3 . ? 1.349 22.495 29.308 1.00 47.43 ? 702 MAN A O4 1 HETATM 4214 O O5 . MAN O 3 . ? 4.081 24.451 29.864 1.00 39.12 ? 702 MAN A O5 1 HETATM 4215 O O6 . MAN O 3 . ? 5.327 22.845 31.557 1.00 56.44 ? 702 MAN A O6 1 HETATM 4216 C C1 . MAN P 3 . ? 19.111 28.794 21.975 1.00 64.16 ? 703 MAN A C1 1 HETATM 4217 C C2 . MAN P 3 . ? 19.332 28.450 23.455 1.00 66.45 ? 703 MAN A C2 1 HETATM 4218 C C3 . MAN P 3 . ? 19.935 29.594 24.301 1.00 72.40 ? 703 MAN A C3 1 HETATM 4219 C C4 . MAN P 3 . ? 19.558 31.004 23.817 1.00 69.29 ? 703 MAN A C4 1 HETATM 4220 C C5 . MAN P 3 . ? 19.470 31.153 22.288 1.00 62.78 ? 703 MAN A C5 1 HETATM 4221 C C6 . MAN P 3 . ? 20.329 32.318 21.810 1.00 58.55 ? 703 MAN A C6 1 HETATM 4222 O O2 . MAN P 3 . ? 20.137 27.289 23.526 1.00 65.03 ? 703 MAN A O2 1 HETATM 4223 O O3 . MAN P 3 . ? 21.346 29.505 24.384 1.00 64.09 ? 703 MAN A O3 1 HETATM 4224 O O4 . MAN P 3 . ? 18.331 31.414 24.393 1.00 63.49 ? 703 MAN A O4 1 HETATM 4225 O O5 . MAN P 3 . ? 19.846 29.961 21.605 1.00 72.45 ? 703 MAN A O5 1 HETATM 4226 O O6 . MAN P 3 . ? 19.744 33.528 22.245 1.00 54.88 ? 703 MAN A O6 1 HETATM 4227 C C1 . MAN Q 3 . ? -17.953 73.458 48.264 1.00 72.59 ? 705 MAN A C1 1 HETATM 4228 C C2 . MAN Q 3 . ? -18.689 72.937 47.034 1.00 77.15 ? 705 MAN A C2 1 HETATM 4229 C C3 . MAN Q 3 . ? -18.842 74.011 45.943 1.00 75.61 ? 705 MAN A C3 1 HETATM 4230 C C4 . MAN Q 3 . ? -18.496 75.452 46.355 1.00 73.85 ? 705 MAN A C4 1 HETATM 4231 C C5 . MAN Q 3 . ? -18.395 75.755 47.863 1.00 81.92 ? 705 MAN A C5 1 HETATM 4232 C C6 . MAN Q 3 . ? -19.363 76.867 48.263 1.00 76.26 ? 705 MAN A C6 1 HETATM 4233 O O2 . MAN Q 3 . ? -19.953 72.439 47.426 1.00 71.96 ? 705 MAN A O2 1 HETATM 4234 O O3 . MAN Q 3 . ? -20.150 73.991 45.406 1.00 71.12 ? 705 MAN A O3 1 HETATM 4235 O O4 . MAN Q 3 . ? -17.275 75.800 45.737 1.00 56.09 ? 705 MAN A O4 1 HETATM 4236 O O5 . MAN Q 3 . ? -18.614 74.627 48.696 1.00 80.01 ? 705 MAN A O5 1 HETATM 4237 O O6 . MAN Q 3 . ? -20.314 76.368 49.182 1.00 80.62 ? 705 MAN A O6 1 HETATM 4238 C C1 . MAN R 3 . ? -14.318 72.433 41.048 1.00 79.81 ? 706 MAN A C1 1 HETATM 4239 C C2 . MAN R 3 . ? -14.170 73.301 39.804 1.00 79.63 ? 706 MAN A C2 1 HETATM 4240 C C3 . MAN R 3 . ? -15.349 74.267 39.737 1.00 91.79 ? 706 MAN A C3 1 HETATM 4241 C C4 . MAN R 3 . ? -16.695 73.551 39.919 1.00 95.41 ? 706 MAN A C4 1 HETATM 4242 C C5 . MAN R 3 . ? -16.663 72.527 41.063 1.00 92.43 ? 706 MAN A C5 1 HETATM 4243 C C6 . MAN R 3 . ? -17.920 71.664 41.079 1.00 88.99 ? 706 MAN A C6 1 HETATM 4244 O O2 . MAN R 3 . ? -14.132 72.488 38.650 1.00 56.03 ? 706 MAN A O2 1 HETATM 4245 O O3 . MAN R 3 . ? -15.312 74.956 38.506 1.00 98.01 ? 706 MAN A O3 1 HETATM 4246 O O4 . MAN R 3 . ? -17.697 74.511 40.177 1.00 86.76 ? 706 MAN A O4 1 HETATM 4247 O O5 . MAN R 3 . ? -15.520 71.692 40.972 1.00 83.17 ? 706 MAN A O5 1 HETATM 4248 O O6 . MAN R 3 . ? -18.621 71.890 42.281 1.00 76.87 ? 706 MAN A O6 1 HETATM 4249 C C1 . MAN S 3 . ? -8.514 69.798 35.719 1.00 74.37 ? 707 MAN A C1 1 HETATM 4250 C C2 . MAN S 3 . ? -9.389 70.033 34.485 1.00 82.90 ? 707 MAN A C2 1 HETATM 4251 C C3 . MAN S 3 . ? -9.072 69.012 33.383 1.00 88.68 ? 707 MAN A C3 1 HETATM 4252 C C4 . MAN S 3 . ? -7.563 68.831 33.160 1.00 87.10 ? 707 MAN A C4 1 HETATM 4253 C C5 . MAN S 3 . ? -6.823 68.724 34.498 1.00 78.48 ? 707 MAN A C5 1 HETATM 4254 C C6 . MAN S 3 . ? -5.313 68.617 34.316 1.00 80.49 ? 707 MAN A C6 1 HETATM 4255 O O2 . MAN S 3 . ? -9.189 71.348 34.009 1.00 78.74 ? 707 MAN A O2 1 HETATM 4256 O O3 . MAN S 3 . ? -9.699 69.398 32.177 1.00 87.63 ? 707 MAN A O3 1 HETATM 4257 O O4 . MAN S 3 . ? -7.332 67.667 32.394 1.00 74.61 ? 707 MAN A O4 1 HETATM 4258 O O5 . MAN S 3 . ? -7.154 69.832 35.320 1.00 71.09 ? 707 MAN A O5 1 HETATM 4259 O O6 . MAN S 3 . ? -4.969 67.250 34.276 1.00 74.71 ? 707 MAN A O6 1 HETATM 4260 C C1 . MAN T 3 . ? -9.217 87.307 81.625 1.00 100.53 ? 708 MAN A C1 1 HETATM 4261 C C2 . MAN T 3 . ? -7.835 86.716 81.921 1.00 105.70 ? 708 MAN A C2 1 HETATM 4262 C C3 . MAN T 3 . ? -7.721 85.262 81.451 1.00 105.49 ? 708 MAN A C3 1 HETATM 4263 C C4 . MAN T 3 . ? -8.935 84.423 81.854 1.00 107.88 ? 708 MAN A C4 1 HETATM 4264 C C5 . MAN T 3 . ? -10.251 85.135 81.531 1.00 105.27 ? 708 MAN A C5 1 HETATM 4265 C C6 . MAN T 3 . ? -11.444 84.373 82.098 1.00 102.53 ? 708 MAN A C6 1 HETATM 4266 O O2 . MAN T 3 . ? -7.563 86.808 83.304 1.00 113.48 ? 708 MAN A O2 1 HETATM 4267 O O3 . MAN T 3 . ? -6.544 84.684 81.970 1.00 103.65 ? 708 MAN A O3 1 HETATM 4268 O O4 . MAN T 3 . ? -8.881 83.191 81.172 1.00 105.61 ? 708 MAN A O4 1 HETATM 4269 O O5 . MAN T 3 . ? -10.259 86.450 82.064 1.00 102.19 ? 708 MAN A O5 1 HETATM 4270 O O6 . MAN T 3 . ? -12.624 85.104 81.854 1.00 103.93 ? 708 MAN A O6 1 HETATM 4271 C C1 . MAN U 3 . ? -4.181 90.731 82.845 1.00 119.30 ? 709 MAN A C1 1 HETATM 4272 C C2 . MAN U 3 . ? -4.870 89.366 82.702 1.00 122.30 ? 709 MAN A C2 1 HETATM 4273 C C3 . MAN U 3 . ? -4.193 88.295 83.563 1.00 131.84 ? 709 MAN A C3 1 HETATM 4274 C C4 . MAN U 3 . ? -2.665 88.350 83.452 1.00 140.98 ? 709 MAN A C4 1 HETATM 4275 C C5 . MAN U 3 . ? -2.182 89.791 83.655 1.00 135.55 ? 709 MAN A C5 1 HETATM 4276 C C6 . MAN U 3 . ? -0.664 89.939 83.586 1.00 139.45 ? 709 MAN A C6 1 HETATM 4277 O O2 . MAN U 3 . ? -4.875 88.951 81.350 1.00 118.40 ? 709 MAN A O2 1 HETATM 4278 O O3 . MAN U 3 . ? -4.661 87.017 83.188 1.00 130.10 ? 709 MAN A O3 1 HETATM 4279 O O4 . MAN U 3 . ? -2.086 87.478 84.401 1.00 147.46 ? 709 MAN A O4 1 HETATM 4280 O O5 . MAN U 3 . ? -2.780 90.606 82.665 1.00 123.95 ? 709 MAN A O5 1 HETATM 4281 O O6 . MAN U 3 . ? -0.269 90.985 84.448 1.00 128.45 ? 709 MAN A O6 1 HETATM 4282 C C1 . MAN V 3 . ? -0.511 97.067 81.134 1.00 112.91 ? 710 MAN A C1 1 HETATM 4283 C C2 . MAN V 3 . ? -1.004 95.748 81.736 1.00 109.17 ? 710 MAN A C2 1 HETATM 4284 C C3 . MAN V 3 . ? -0.120 95.290 82.904 1.00 106.48 ? 710 MAN A C3 1 HETATM 4285 C C4 . MAN V 3 . ? 1.376 95.362 82.581 1.00 108.67 ? 710 MAN A C4 1 HETATM 4286 C C5 . MAN V 3 . ? 1.775 96.659 81.860 1.00 115.01 ? 710 MAN A C5 1 HETATM 4287 C C6 . MAN V 3 . ? 3.176 96.520 81.260 1.00 125.13 ? 710 MAN A C6 1 HETATM 4288 O O2 . MAN V 3 . ? -1.071 94.756 80.732 1.00 106.04 ? 710 MAN A O2 1 HETATM 4289 O O3 . MAN V 3 . ? -0.466 93.974 83.285 1.00 103.93 ? 710 MAN A O3 1 HETATM 4290 O O4 . MAN V 3 . ? 2.106 95.254 83.788 1.00 100.58 ? 710 MAN A O4 1 HETATM 4291 O O5 . MAN V 3 . ? 0.874 97.006 80.812 1.00 117.71 ? 710 MAN A O5 1 HETATM 4292 O O6 . MAN V 3 . ? 3.480 97.830 80.554 1.00 125.20 ? 710 MAN A O6 1 HETATM 4293 C C1 . NAG W 4 . ? 10.436 31.693 34.894 1.00 65.74 ? 801 NAG A C1 1 HETATM 4294 C C2 . NAG W 4 . ? 11.603 30.709 34.703 1.00 74.52 ? 801 NAG A C2 1 HETATM 4295 C C3 . NAG W 4 . ? 11.181 29.301 35.136 1.00 69.72 ? 801 NAG A C3 1 HETATM 4296 C C4 . NAG W 4 . ? 10.454 29.268 36.488 1.00 86.83 ? 801 NAG A C4 1 HETATM 4297 C C5 . NAG W 4 . ? 9.568 30.501 36.754 1.00 81.28 ? 801 NAG A C5 1 HETATM 4298 C C6 . NAG W 4 . ? 9.261 30.663 38.243 1.00 74.88 ? 801 NAG A C6 1 HETATM 4299 C C7 . NAG W 4 . ? 13.406 30.607 33.024 1.00 74.08 ? 801 NAG A C7 1 HETATM 4300 C C8 . NAG W 4 . ? 13.898 29.327 32.409 1.00 54.49 ? 801 NAG A C8 1 HETATM 4301 N N2 . NAG W 4 . ? 12.104 30.677 33.333 1.00 76.83 ? 801 NAG A N2 1 HETATM 4302 O O3 . NAG W 4 . ? 12.323 28.475 35.209 1.00 64.18 ? 801 NAG A O3 1 HETATM 4303 O O4 . NAG W 4 . ? 9.675 28.086 36.541 1.00 81.50 ? 801 NAG A O4 1 HETATM 4304 O O5 . NAG W 4 . ? 10.186 31.690 36.290 1.00 66.02 ? 801 NAG A O5 1 HETATM 4305 O O6 . NAG W 4 . ? 7.994 31.267 38.413 1.00 53.52 ? 801 NAG A O6 1 HETATM 4306 O O7 . NAG W 4 . ? 14.193 31.538 33.213 1.00 82.10 ? 801 NAG A O7 1 HETATM 4307 C C1 . NAG X 4 . ? 10.596 29.889 7.208 1.00 39.66 ? 802 NAG A C1 1 HETATM 4308 C C2 . NAG X 4 . ? 9.567 29.089 6.411 1.00 43.58 ? 802 NAG A C2 1 HETATM 4309 C C3 . NAG X 4 . ? 9.804 29.155 4.906 1.00 46.84 ? 802 NAG A C3 1 HETATM 4310 C C4 . NAG X 4 . ? 10.214 30.547 4.401 1.00 51.88 ? 802 NAG A C4 1 HETATM 4311 C C5 . NAG X 4 . ? 11.192 31.238 5.363 1.00 50.21 ? 802 NAG A C5 1 HETATM 4312 C C6 . NAG X 4 . ? 11.443 32.703 5.005 1.00 52.86 ? 802 NAG A C6 1 HETATM 4313 C C7 . NAG X 4 . ? 8.437 27.102 7.235 1.00 43.87 ? 802 NAG A C7 1 HETATM 4314 C C8 . NAG X 4 . ? 8.034 25.857 6.498 1.00 41.17 ? 802 NAG A C8 1 HETATM 4315 N N2 . NAG X 4 . ? 9.558 27.696 6.823 1.00 40.57 ? 802 NAG A N2 1 HETATM 4316 O O3 . NAG X 4 . ? 8.605 28.757 4.276 1.00 50.07 ? 802 NAG A O3 1 HETATM 4317 O O4 . NAG X 4 . ? 10.811 30.436 3.116 1.00 60.20 ? 802 NAG A O4 1 HETATM 4318 O O5 . NAG X 4 . ? 10.700 31.193 6.685 1.00 40.59 ? 802 NAG A O5 1 HETATM 4319 O O6 . NAG X 4 . ? 10.254 33.450 5.151 1.00 51.77 ? 802 NAG A O6 1 HETATM 4320 O O7 . NAG X 4 . ? 7.743 27.527 8.166 1.00 36.35 ? 802 NAG A O7 1 HETATM 4321 C C1 . NAG Y 4 . ? 9.943 30.919 2.060 1.00 63.10 ? 803 NAG A C1 1 HETATM 4322 C C2 . NAG Y 4 . ? 10.754 31.047 0.759 1.00 65.10 ? 803 NAG A C2 1 HETATM 4323 C C3 . NAG Y 4 . ? 9.899 31.203 -0.509 1.00 67.58 ? 803 NAG A C3 1 HETATM 4324 C C4 . NAG Y 4 . ? 8.604 30.377 -0.488 1.00 81.68 ? 803 NAG A C4 1 HETATM 4325 C C5 . NAG Y 4 . ? 7.904 30.452 0.876 1.00 75.45 ? 803 NAG A C5 1 HETATM 4326 C C6 . NAG Y 4 . ? 6.711 29.503 0.952 1.00 74.16 ? 803 NAG A C6 1 HETATM 4327 C C7 . NAG Y 4 . ? 12.989 32.049 0.920 1.00 58.82 ? 803 NAG A C7 1 HETATM 4328 C C8 . NAG Y 4 . ? 13.752 32.222 -0.368 1.00 62.48 ? 803 NAG A C8 1 HETATM 4329 N N2 . NAG Y 4 . ? 11.662 32.183 0.853 1.00 60.87 ? 803 NAG A N2 1 HETATM 4330 O O3 . NAG Y 4 . ? 10.665 30.841 -1.643 1.00 57.47 ? 803 NAG A O3 1 HETATM 4331 O O4 . NAG Y 4 . ? 7.737 30.813 -1.523 1.00 75.10 ? 803 NAG A O4 1 HETATM 4332 O O5 . NAG Y 4 . ? 8.804 30.086 1.903 1.00 64.65 ? 803 NAG A O5 1 HETATM 4333 O O6 . NAG Y 4 . ? 5.527 30.255 1.092 1.00 80.11 ? 803 NAG A O6 1 HETATM 4334 O O7 . NAG Y 4 . ? 13.582 31.802 1.973 1.00 42.86 ? 803 NAG A O7 1 HETATM 4335 C C1 . NAG Z 4 . ? -8.158 60.147 55.800 1.00 101.58 ? 804 NAG A C1 1 HETATM 4336 C C2 . NAG Z 4 . ? -8.269 58.622 55.742 1.00 106.13 ? 804 NAG A C2 1 HETATM 4337 C C3 . NAG Z 4 . ? -8.408 58.089 57.167 1.00 103.23 ? 804 NAG A C3 1 HETATM 4338 C C4 . NAG Z 4 . ? -7.202 58.528 58.004 1.00 107.13 ? 804 NAG A C4 1 HETATM 4339 C C5 . NAG Z 4 . ? -6.883 60.025 57.842 1.00 103.47 ? 804 NAG A C5 1 HETATM 4340 C C6 . NAG Z 4 . ? -5.483 60.354 58.366 1.00 101.21 ? 804 NAG A C6 1 HETATM 4341 C C7 . NAG Z 4 . ? -9.161 57.161 53.998 1.00 97.94 ? 804 NAG A C7 1 HETATM 4342 C C8 . NAG Z 4 . ? -10.354 56.301 53.690 1.00 87.64 ? 804 NAG A C8 1 HETATM 4343 N N2 . NAG Z 4 . ? -9.341 58.163 54.867 1.00 106.89 ? 804 NAG A N2 1 HETATM 4344 O O3 . NAG Z 4 . ? -8.489 56.681 57.155 1.00 101.44 ? 804 NAG A O3 1 HETATM 4345 O O4 . NAG Z 4 . ? -7.441 58.219 59.363 1.00 104.95 ? 804 NAG A O4 1 HETATM 4346 O O5 . NAG Z 4 . ? -6.955 60.455 56.488 1.00 99.75 ? 804 NAG A O5 1 HETATM 4347 O O6 . NAG Z 4 . ? -4.514 60.175 57.350 1.00 88.79 ? 804 NAG A O6 1 HETATM 4348 O O7 . NAG Z 4 . ? -8.080 56.924 53.455 1.00 89.96 ? 804 NAG A O7 1 HETATM 4349 C C1 . NAG AA 4 . ? 4.333 102.830 87.551 1.00 100.21 ? 805 NAG A C1 1 HETATM 4350 C C2 . NAG AA 4 . ? 5.268 102.154 88.559 1.00 105.49 ? 805 NAG A C2 1 HETATM 4351 C C3 . NAG AA 4 . ? 6.638 102.843 88.623 1.00 102.91 ? 805 NAG A C3 1 HETATM 4352 C C4 . NAG AA 4 . ? 7.254 102.990 87.230 1.00 106.63 ? 805 NAG A C4 1 HETATM 4353 C C5 . NAG AA 4 . ? 6.257 103.641 86.265 1.00 101.75 ? 805 NAG A C5 1 HETATM 4354 C C6 . NAG AA 4 . ? 6.116 102.861 84.958 1.00 107.65 ? 805 NAG A C6 1 HETATM 4355 C C7 . NAG AA 4 . ? 4.692 102.901 90.864 1.00 107.44 ? 805 NAG A C7 1 HETATM 4356 C C8 . NAG AA 4 . ? 5.146 102.335 92.178 1.00 102.27 ? 805 NAG A C8 1 HETATM 4357 N N2 . NAG AA 4 . ? 4.607 102.032 89.855 1.00 102.95 ? 805 NAG A N2 1 HETATM 4358 O O3 . NAG AA 4 . ? 7.509 102.110 89.453 1.00 105.32 ? 805 NAG A O3 1 HETATM 4359 O O4 . NAG AA 4 . ? 8.408 103.805 87.292 1.00 105.66 ? 805 NAG A O4 1 HETATM 4360 O O5 . NAG AA 4 . ? 4.988 103.891 86.871 1.00 93.96 ? 805 NAG A O5 1 HETATM 4361 O O6 . NAG AA 4 . ? 7.176 103.198 84.091 1.00 105.51 ? 805 NAG A O6 1 HETATM 4362 O O7 . NAG AA 4 . ? 4.412 104.096 90.763 1.00 113.46 ? 805 NAG A O7 1 HETATM 4363 C C1 . NAG BA 4 . ? 9.609 103.090 86.930 1.00 109.23 ? 806 NAG A C1 1 HETATM 4364 C C2 . NAG BA 4 . ? 10.547 104.068 86.211 1.00 109.13 ? 806 NAG A C2 1 HETATM 4365 C C3 . NAG BA 4 . ? 12.020 103.626 86.167 1.00 117.73 ? 806 NAG A C3 1 HETATM 4366 C C4 . NAG BA 4 . ? 12.488 102.884 87.419 1.00 122.70 ? 806 NAG A C4 1 HETATM 4367 C C5 . NAG BA 4 . ? 11.453 101.838 87.838 1.00 127.54 ? 806 NAG A C5 1 HETATM 4368 C C6 . NAG BA 4 . ? 11.868 101.099 89.111 1.00 133.00 ? 806 NAG A C6 1 HETATM 4369 C C7 . NAG BA 4 . ? 10.287 105.362 84.135 1.00 108.80 ? 806 NAG A C7 1 HETATM 4370 C C8 . NAG BA 4 . ? 11.055 105.174 82.856 1.00 91.79 ? 806 NAG A C8 1 HETATM 4371 N N2 . NAG BA 4 . ? 10.051 104.265 84.857 1.00 111.81 ? 806 NAG A N2 1 HETATM 4372 O O3 . NAG BA 4 . ? 12.845 104.756 85.981 1.00 120.71 ? 806 NAG A O3 1 HETATM 4373 O O4 . NAG BA 4 . ? 13.745 102.291 87.162 1.00 115.52 ? 806 NAG A O4 1 HETATM 4374 O O5 . NAG BA 4 . ? 10.212 102.486 88.064 1.00 123.30 ? 806 NAG A O5 1 HETATM 4375 O O6 . NAG BA 4 . ? 12.325 99.801 88.797 1.00 130.12 ? 806 NAG A O6 1 HETATM 4376 O O7 . NAG BA 4 . ? 9.901 106.481 84.473 1.00 95.84 ? 806 NAG A O7 1 HETATM 4377 C C1 . NAG CA 4 . ? 8.190 134.541 127.183 1.00 81.10 ? 807 NAG A C1 1 HETATM 4378 C C2 . NAG CA 4 . ? 7.187 133.398 127.367 1.00 79.98 ? 807 NAG A C2 1 HETATM 4379 C C3 . NAG CA 4 . ? 6.322 133.637 128.604 1.00 80.87 ? 807 NAG A C3 1 HETATM 4380 C C4 . NAG CA 4 . ? 7.207 133.811 129.837 1.00 86.77 ? 807 NAG A C4 1 HETATM 4381 C C5 . NAG CA 4 . ? 8.296 134.867 129.593 1.00 88.59 ? 807 NAG A C5 1 HETATM 4382 C C6 . NAG CA 4 . ? 9.323 134.861 130.723 1.00 85.01 ? 807 NAG A C6 1 HETATM 4383 C C7 . NAG CA 4 . ? 6.628 132.231 125.314 1.00 83.76 ? 807 NAG A C7 1 HETATM 4384 C C8 . NAG CA 4 . ? 5.600 131.141 125.203 1.00 81.59 ? 807 NAG A C8 1 HETATM 4385 N N2 . NAG CA 4 . ? 6.373 133.214 126.179 1.00 80.59 ? 807 NAG A N2 1 HETATM 4386 O O3 . NAG CA 4 . ? 5.447 132.550 128.801 1.00 78.01 ? 807 NAG A O3 1 HETATM 4387 O O4 . NAG CA 4 . ? 6.407 134.162 130.949 1.00 84.32 ? 807 NAG A O4 1 HETATM 4388 O O5 . NAG CA 4 . ? 8.985 134.664 128.360 1.00 89.65 ? 807 NAG A O5 1 HETATM 4389 O O6 . NAG CA 4 . ? 8.868 135.671 131.784 1.00 82.24 ? 807 NAG A O6 1 HETATM 4390 O O7 . NAG CA 4 . ? 7.652 132.196 124.627 1.00 77.50 ? 807 NAG A O7 1 HETATM 4391 O O . HOH DA 5 . ? 25.894 -2.228 3.897 1.00 17.53 ? 559 HOH A O 1 HETATM 4392 O O . HOH DA 5 . ? 39.138 9.767 6.490 1.00 12.33 ? 560 HOH A O 1 HETATM 4393 O O . HOH DA 5 . ? 37.399 -10.066 -3.112 1.00 9.96 ? 561 HOH A O 1 HETATM 4394 O O . HOH DA 5 . ? 43.986 -14.165 1.767 1.00 12.18 ? 562 HOH A O 1 HETATM 4395 O O . HOH DA 5 . ? 48.659 -20.826 -1.199 1.00 29.90 ? 563 HOH A O 1 HETATM 4396 O O . HOH DA 5 . ? 31.263 -11.367 17.491 1.00 20.26 ? 564 HOH A O 1 HETATM 4397 O O . HOH DA 5 . ? 12.239 45.117 18.221 1.00 6.97 ? 565 HOH A O 1 HETATM 4398 O O . HOH DA 5 . ? 51.793 0.627 5.936 1.00 25.12 ? 566 HOH A O 1 HETATM 4399 O O . HOH DA 5 . ? 56.758 -6.199 6.625 1.00 23.91 ? 567 HOH A O 1 HETATM 4400 O O . HOH DA 5 . ? 35.194 6.223 0.940 1.00 24.88 ? 568 HOH A O 1 HETATM 4401 O O . HOH DA 5 . ? 20.520 0.943 16.297 1.00 15.93 ? 569 HOH A O 1 HETATM 4402 O O . HOH DA 5 . ? 15.869 -7.203 7.050 1.00 36.14 ? 570 HOH A O 1 HETATM 4403 O O . HOH DA 5 . ? 35.140 -13.189 1.780 1.00 22.85 ? 571 HOH A O 1 HETATM 4404 O O . HOH DA 5 . ? 46.382 -14.244 -4.709 1.00 31.43 ? 572 HOH A O 1 HETATM 4405 O O . HOH DA 5 . ? 41.621 -13.160 -3.921 1.00 27.77 ? 573 HOH A O 1 HETATM 4406 O O . HOH DA 5 . ? 43.293 -15.471 -2.215 1.00 29.60 ? 574 HOH A O 1 HETATM 4407 O O . HOH DA 5 . ? 41.524 -17.778 0.501 1.00 13.43 ? 575 HOH A O 1 HETATM 4408 O O . HOH DA 5 . ? 39.213 -20.790 10.516 1.00 16.10 ? 576 HOH A O 1 HETATM 4409 O O . HOH DA 5 . ? 37.831 -9.414 21.103 1.00 18.53 ? 577 HOH A O 1 HETATM 4410 O O . HOH DA 5 . ? 34.290 -14.148 11.398 1.00 12.41 ? 578 HOH A O 1 HETATM 4411 O O . HOH DA 5 . ? 31.641 -9.600 0.167 1.00 15.63 ? 579 HOH A O 1 HETATM 4412 O O . HOH DA 5 . ? 27.953 1.554 18.892 1.00 6.31 ? 580 HOH A O 1 HETATM 4413 O O . HOH DA 5 . ? 43.529 2.110 15.620 1.00 20.47 ? 581 HOH A O 1 HETATM 4414 O O . HOH DA 5 . ? 49.259 -1.704 15.219 1.00 19.50 ? 582 HOH A O 1 HETATM 4415 O O . HOH DA 5 . ? 12.744 9.795 18.751 1.00 15.66 ? 583 HOH A O 1 HETATM 4416 O O . HOH DA 5 . ? 8.661 37.700 32.187 1.00 25.32 ? 584 HOH A O 1 HETATM 4417 O O . HOH DA 5 . ? 8.742 44.556 29.217 1.00 21.19 ? 585 HOH A O 1 HETATM 4418 O O . HOH DA 5 . ? 5.994 50.515 25.795 1.00 16.93 ? 586 HOH A O 1 HETATM 4419 O O . HOH DA 5 . ? 18.172 39.314 19.269 1.00 25.07 ? 587 HOH A O 1 HETATM 4420 O O . HOH DA 5 . ? 8.909 40.989 33.689 1.00 18.74 ? 588 HOH A O 1 HETATM 4421 O O . HOH DA 5 . ? 26.525 15.313 16.102 1.00 13.82 ? 589 HOH A O 1 HETATM 4422 O O . HOH DA 5 . ? 20.953 28.565 12.453 1.00 31.76 ? 590 HOH A O 1 HETATM 4423 O O . HOH DA 5 . ? 14.936 29.275 4.582 1.00 26.65 ? 591 HOH A O 1 HETATM 4424 O O . HOH DA 5 . ? 6.914 31.586 11.461 1.00 15.08 ? 592 HOH A O 1 HETATM 4425 O O . HOH DA 5 . ? -6.821 44.313 18.364 1.00 17.96 ? 593 HOH A O 1 HETATM 4426 O O . HOH DA 5 . ? -1.144 36.240 35.566 1.00 38.60 ? 594 HOH A O 1 HETATM 4427 O O . HOH DA 5 . ? -10.525 55.132 33.278 1.00 25.58 ? 595 HOH A O 1 HETATM 4428 O O . HOH DA 5 . ? 4.713 54.765 31.676 1.00 25.44 ? 596 HOH A O 1 HETATM 4429 O O . HOH DA 5 . ? -6.530 89.385 70.598 1.00 58.75 ? 597 HOH A O 1 HETATM 4430 O O . HOH DA 5 . ? -8.705 97.026 78.331 1.00 47.97 ? 598 HOH A O 1 HETATM 4431 O O . HOH DA 5 . ? 41.145 -8.363 -2.950 1.00 22.65 ? 599 HOH A O 1 HETATM 4432 O O . HOH DA 5 . ? 41.538 -12.878 13.631 1.00 13.76 ? 600 HOH A O 1 HETATM 4433 O O . HOH DA 5 . ? 33.103 9.369 17.089 1.00 16.23 ? 613 HOH A O 1 HETATM 4434 O O . HOH DA 5 . ? 50.392 -7.044 10.922 1.00 15.28 ? 614 HOH A O 1 HETATM 4435 O O . HOH DA 5 . ? -1.551 27.899 24.513 1.00 21.02 ? 615 HOH A O 1 HETATM 4436 O O . HOH DA 5 . ? -3.051 31.554 30.263 1.00 13.78 ? 616 HOH A O 1 HETATM 4437 O O . HOH DA 5 . ? -8.264 55.405 35.877 1.00 32.11 ? 617 HOH A O 1 HETATM 4438 O O . HOH DA 5 . ? 37.389 0.535 1.317 1.00 11.59 ? 618 HOH A O 1 HETATM 4439 O O . HOH DA 5 . ? 28.921 -1.515 2.301 1.00 15.13 ? 619 HOH A O 1 HETATM 4440 O O . HOH DA 5 . ? 25.688 -10.127 4.820 1.00 29.45 ? 620 HOH A O 1 HETATM 4441 O O . HOH DA 5 . ? 39.608 -8.279 17.492 1.00 13.81 ? 621 HOH A O 1 HETATM 4442 O O . HOH DA 5 . ? 35.278 -12.557 16.280 1.00 9.94 ? 622 HOH A O 1 HETATM 4443 O O . HOH DA 5 . ? 36.508 -18.750 5.398 1.00 15.19 ? 623 HOH A O 1 HETATM 4444 O O . HOH DA 5 . ? 23.279 -7.788 16.870 1.00 16.80 ? 624 HOH A O 1 HETATM 4445 O O . HOH DA 5 . ? 59.271 -19.216 8.055 1.00 13.71 ? 625 HOH A O 1 HETATM 4446 O O . HOH DA 5 . ? 19.020 28.795 16.586 1.00 24.61 ? 626 HOH A O 1 HETATM 4447 O O . HOH DA 5 . ? -3.972 35.233 39.015 1.00 24.71 ? 627 HOH A O 1 HETATM 4448 O O . HOH DA 5 . ? 13.044 19.480 3.907 1.00 39.39 ? 628 HOH A O 1 HETATM 4449 O O . HOH DA 5 . ? 46.694 -17.930 1.420 1.00 25.02 ? 629 HOH A O 1 HETATM 4450 O O . HOH DA 5 . ? 45.313 -16.907 3.775 1.00 13.63 ? 630 HOH A O 1 HETATM 4451 O O . HOH DA 5 . ? 10.781 7.068 6.995 1.00 9.71 ? 631 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ASP 1 1 1 ASP ASP A . n A 1 2 TRP 2 2 2 TRP TRP A . n A 1 3 VAL 3 3 3 VAL VAL A . n A 1 4 ILE 4 4 4 ILE ILE A . n A 1 5 PRO 5 5 5 PRO PRO A . n A 1 6 PRO 6 6 6 PRO PRO A . n A 1 7 ILE 7 7 7 ILE ILE A . n A 1 8 ASN 8 8 8 ASN ASN A . n A 1 9 LEU 9 9 9 LEU LEU A . n A 1 10 PRO 10 10 10 PRO PRO A . n A 1 11 GLU 11 11 11 GLU GLU A . n A 1 12 ASN 12 12 12 ASN ASN A . n A 1 13 SER 13 13 13 SER SER A . n A 1 14 ARG 14 14 14 ARG ARG A . n A 1 15 GLY 15 15 15 GLY GLY A . n A 1 16 PRO 16 16 16 PRO PRO A . n A 1 17 PHE 17 17 17 PHE PHE A . n A 1 18 PRO 18 18 18 PRO PRO A . n A 1 19 GLN 19 19 19 GLN GLN A . n A 1 20 GLU 20 20 20 GLU GLU A . n A 1 21 LEU 21 21 21 LEU LEU A . n A 1 22 VAL 22 22 22 VAL VAL A . n A 1 23 ARG 23 23 23 ARG ARG A . n A 1 24 ILE 24 24 24 ILE ILE A . n A 1 25 ARG 25 25 25 ARG ARG A . n A 1 26 SER 26 26 26 SER SER A . n A 1 27 ASP 27 27 27 ASP ASP A . n A 1 28 ARG 28 28 28 ARG ARG A . n A 1 29 ASP 29 29 29 ASP ASP A . n A 1 30 LYS 30 30 30 LYS LYS A . n A 1 31 ASN 31 31 31 ASN ASN A . n A 1 32 LEU 32 32 32 LEU LEU A . n A 1 33 SER 33 33 33 SER SER A . n A 1 34 LEU 34 34 34 LEU LEU A . n A 1 35 ARG 35 35 35 ARG ARG A . n A 1 36 TYR 36 36 36 TYR TYR A . n A 1 37 SER 37 37 37 SER SER A . n A 1 38 VAL 38 38 38 VAL VAL A . n A 1 39 THR 39 39 39 THR THR A . n A 1 40 GLY 40 40 40 GLY GLY A . n A 1 41 PRO 41 41 41 PRO PRO A . n A 1 42 GLY 42 42 42 GLY GLY A . n A 1 43 ALA 43 43 43 ALA ALA A . n A 1 44 ASP 44 44 44 ASP ASP A . n A 1 45 GLN 45 45 45 GLN GLN A . n A 1 46 PRO 46 46 46 PRO PRO A . n A 1 47 PRO 47 47 47 PRO PRO A . n A 1 48 THR 48 48 48 THR THR A . n A 1 49 GLY 49 49 49 GLY GLY A . n A 1 50 ILE 50 50 50 ILE ILE A . n A 1 51 PHE 51 51 51 PHE PHE A . n A 1 52 ILE 52 52 52 ILE ILE A . n A 1 53 ILE 53 53 53 ILE ILE A . n A 1 54 ASN 54 54 54 ASN ASN A . n A 1 55 PRO 55 55 55 PRO PRO A . n A 1 56 ILE 56 56 56 ILE ILE A . n A 1 57 SER 57 57 57 SER SER A . n A 1 58 GLY 58 58 58 GLY GLY A . n A 1 59 GLN 59 59 59 GLN GLN A . n A 1 60 LEU 60 60 60 LEU LEU A . n A 1 61 SER 61 61 61 SER SER A . n A 1 62 VAL 62 62 62 VAL VAL A . n A 1 63 THR 63 63 63 THR THR A . n A 1 64 LYS 64 64 64 LYS LYS A . n A 1 65 PRO 65 65 65 PRO PRO A . n A 1 66 LEU 66 66 66 LEU LEU A . n A 1 67 ASP 67 67 67 ASP ASP A . n A 1 68 ARG 68 68 68 ARG ARG A . n A 1 69 GLU 69 69 69 GLU GLU A . n A 1 70 LEU 70 70 70 LEU LEU A . n A 1 71 ILE 71 71 71 ILE ILE A . n A 1 72 ALA 72 72 72 ALA ALA A . n A 1 73 ARG 73 73 73 ARG ARG A . n A 1 74 PHE 74 74 74 PHE PHE A . n A 1 75 HIS 75 75 75 HIS HIS A . n A 1 76 LEU 76 76 76 LEU LEU A . n A 1 77 ARG 77 77 77 ARG ARG A . n A 1 78 ALA 78 78 78 ALA ALA A . n A 1 79 HIS 79 79 79 HIS HIS A . n A 1 80 ALA 80 80 80 ALA ALA A . n A 1 81 VAL 81 81 81 VAL VAL A . n A 1 82 ASP 82 82 82 ASP ASP A . n A 1 83 ILE 83 83 83 ILE ILE A . n A 1 84 ASN 84 84 84 ASN ASN A . n A 1 85 GLY 85 85 85 GLY GLY A . n A 1 86 ASN 86 86 86 ASN ASN A . n A 1 87 GLN 87 87 87 GLN GLN A . n A 1 88 VAL 88 88 88 VAL VAL A . n A 1 89 GLU 89 89 89 GLU GLU A . n A 1 90 ASN 90 90 90 ASN ASN A . n A 1 91 PRO 91 91 91 PRO PRO A . n A 1 92 ILE 92 92 92 ILE ILE A . n A 1 93 ASP 93 93 93 ASP ASP A . n A 1 94 ILE 94 94 94 ILE ILE A . n A 1 95 VAL 95 95 95 VAL VAL A . n A 1 96 ILE 96 96 96 ILE ILE A . n A 1 97 ASN 97 97 97 ASN ASN A . n A 1 98 VAL 98 98 98 VAL VAL A . n A 1 99 ILE 99 99 99 ILE ILE A . n A 1 100 ASP 100 100 100 ASP ASP A . n A 1 101 MET 101 101 101 MET MET A . n A 1 102 ASN 102 102 102 ASN ASN A . n A 1 103 ASP 103 103 103 ASP ASP A . n A 1 104 ASN 104 104 104 ASN ASN A . n A 1 105 ARG 105 105 105 ARG ARG A . n A 1 106 PRO 106 106 106 PRO PRO A . n A 1 107 GLU 107 107 107 GLU GLU A . n A 1 108 PHE 108 108 108 PHE PHE A . n A 1 109 LEU 109 109 109 LEU LEU A . n A 1 110 HIS 110 110 110 HIS HIS A . n A 1 111 GLN 111 111 111 GLN GLN A . n A 1 112 VAL 112 112 112 VAL VAL A . n A 1 113 TRP 113 113 113 TRP TRP A . n A 1 114 ASN 114 114 114 ASN ASN A . n A 1 115 GLY 115 115 115 GLY GLY A . n A 1 116 SER 116 116 116 SER SER A . n A 1 117 VAL 117 117 117 VAL VAL A . n A 1 118 PRO 118 118 118 PRO PRO A . n A 1 119 GLU 119 119 119 GLU GLU A . n A 1 120 GLY 120 120 120 GLY GLY A . n A 1 121 SER 121 121 121 SER SER A . n A 1 122 LYS 122 122 122 LYS LYS A . n A 1 123 PRO 123 123 123 PRO PRO A . n A 1 124 GLY 124 124 124 GLY GLY A . n A 1 125 THR 125 125 125 THR THR A . n A 1 126 TYR 126 126 126 TYR TYR A . n A 1 127 VAL 127 127 127 VAL VAL A . n A 1 128 MET 128 128 128 MET MET A . n A 1 129 THR 129 129 129 THR THR A . n A 1 130 VAL 130 130 130 VAL VAL A . n A 1 131 THR 131 131 131 THR THR A . n A 1 132 ALA 132 132 132 ALA ALA A . n A 1 133 ILE 133 133 133 ILE ILE A . n A 1 134 ASP 134 134 134 ASP ASP A . n A 1 135 ALA 135 135 135 ALA ALA A . n A 1 136 ASP 136 136 136 ASP ASP A . n A 1 137 ASP 137 137 137 ASP ASP A . n A 1 138 PRO 138 138 138 PRO PRO A . n A 1 139 ASN 139 139 139 ASN ASN A . n A 1 140 ALA 140 140 140 ALA ALA A . n A 1 141 LEU 141 141 141 LEU LEU A . n A 1 142 ASN 142 142 142 ASN ASN A . n A 1 143 GLY 143 143 143 GLY GLY A . n A 1 144 MET 144 144 144 MET MET A . n A 1 145 LEU 145 145 145 LEU LEU A . n A 1 146 ARG 146 146 146 ARG ARG A . n A 1 147 TYR 147 147 147 TYR TYR A . n A 1 148 ARG 148 148 148 ARG ARG A . n A 1 149 ILE 149 149 149 ILE ILE A . n A 1 150 LEU 150 150 150 LEU LEU A . n A 1 151 SER 151 151 151 SER SER A . n A 1 152 GLN 152 152 152 GLN GLN A . n A 1 153 ALA 153 153 153 ALA ALA A . n A 1 154 PRO 154 154 154 PRO PRO A . n A 1 155 SER 155 155 155 SER SER A . n A 1 156 THR 156 156 156 THR THR A . n A 1 157 PRO 157 157 157 PRO PRO A . n A 1 158 SER 158 158 158 SER SER A . n A 1 159 PRO 159 159 159 PRO PRO A . n A 1 160 ASN 160 160 160 ASN ASN A . n A 1 161 MET 161 161 161 MET MET A . n A 1 162 PHE 162 162 162 PHE PHE A . n A 1 163 THR 163 163 163 THR THR A . n A 1 164 ILE 164 164 164 ILE ILE A . n A 1 165 ASN 165 165 165 ASN ASN A . n A 1 166 ASN 166 166 166 ASN ASN A . n A 1 167 GLU 167 167 167 GLU GLU A . n A 1 168 THR 168 168 168 THR THR A . n A 1 169 GLY 169 169 169 GLY GLY A . n A 1 170 ASP 170 170 170 ASP ASP A . n A 1 171 ILE 171 171 171 ILE ILE A . n A 1 172 ILE 172 172 172 ILE ILE A . n A 1 173 THR 173 173 173 THR THR A . n A 1 174 VAL 174 174 174 VAL VAL A . n A 1 175 ALA 175 175 175 ALA ALA A . n A 1 176 ALA 176 176 176 ALA ALA A . n A 1 177 GLY 177 177 177 GLY GLY A . n A 1 178 LEU 178 178 178 LEU LEU A . n A 1 179 ASP 179 179 179 ASP ASP A . n A 1 180 ARG 180 180 180 ARG ARG A . n A 1 181 GLU 181 181 181 GLU GLU A . n A 1 182 LYS 182 182 182 LYS LYS A . n A 1 183 VAL 183 183 183 VAL VAL A . n A 1 184 GLN 184 184 184 GLN GLN A . n A 1 185 GLN 185 185 185 GLN GLN A . n A 1 186 TYR 186 186 186 TYR TYR A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 LEU 188 188 188 LEU LEU A . n A 1 189 ILE 189 189 189 ILE ILE A . n A 1 190 ILE 190 190 190 ILE ILE A . n A 1 191 GLN 191 191 191 GLN GLN A . n A 1 192 ALA 192 192 192 ALA ALA A . n A 1 193 THR 193 193 193 THR THR A . n A 1 194 ASP 194 194 194 ASP ASP A . n A 1 195 MET 195 195 195 MET MET A . n A 1 196 GLU 196 196 196 GLU GLU A . n A 1 197 GLY 197 197 197 GLY GLY A . n A 1 198 ASN 198 198 198 ASN ASN A . n A 1 199 PRO 199 199 199 PRO PRO A . n A 1 200 THR 200 200 200 THR THR A . n A 1 201 TYR 201 201 201 TYR TYR A . n A 1 202 GLY 202 202 202 GLY GLY A . n A 1 203 LEU 203 203 203 LEU LEU A . n A 1 204 SER 204 204 204 SER SER A . n A 1 205 ASN 205 205 205 ASN ASN A . n A 1 206 THR 206 206 206 THR THR A . n A 1 207 ALA 207 207 207 ALA ALA A . n A 1 208 THR 208 208 208 THR THR A . n A 1 209 ALA 209 209 209 ALA ALA A . n A 1 210 VAL 210 210 210 VAL VAL A . n A 1 211 ILE 211 211 211 ILE ILE A . n A 1 212 THR 212 212 212 THR THR A . n A 1 213 VAL 213 213 213 VAL VAL A . n A 1 214 THR 214 214 214 THR THR A . n A 1 215 ASP 215 215 215 ASP ASP A . n A 1 216 VAL 216 216 216 VAL VAL A . n A 1 217 ASN 217 217 217 ASN ASN A . n A 1 218 ASP 218 218 218 ASP ASP A . n A 1 219 ASN 219 219 219 ASN ASN A . n A 1 220 PRO 220 220 220 PRO PRO A . n A 1 221 PRO 221 221 221 PRO PRO A . n A 1 222 GLU 222 222 222 GLU GLU A . n A 1 223 PHE 223 223 223 PHE PHE A . n A 1 224 THR 224 224 224 THR THR A . n A 1 225 ALA 225 225 225 ALA ALA A . n A 1 226 MET 226 226 226 MET MET A . n A 1 227 THR 227 227 227 THR THR A . n A 1 228 PHE 228 228 228 PHE PHE A . n A 1 229 TYR 229 229 229 TYR TYR A . n A 1 230 GLY 230 230 230 GLY GLY A . n A 1 231 GLU 231 231 231 GLU GLU A . n A 1 232 VAL 232 232 232 VAL VAL A . n A 1 233 PRO 233 233 233 PRO PRO A . n A 1 234 GLU 234 234 234 GLU GLU A . n A 1 235 ASN 235 235 235 ASN ASN A . n A 1 236 ARG 236 236 236 ARG ARG A . n A 1 237 VAL 237 237 237 VAL VAL A . n A 1 238 ASP 238 238 238 ASP ASP A . n A 1 239 VAL 239 239 239 VAL VAL A . n A 1 240 ILE 240 240 240 ILE ILE A . n A 1 241 VAL 241 241 241 VAL VAL A . n A 1 242 ALA 242 242 242 ALA ALA A . n A 1 243 ASN 243 243 243 ASN ASN A . n A 1 244 LEU 244 244 244 LEU LEU A . n A 1 245 THR 245 245 245 THR THR A . n A 1 246 VAL 246 246 246 VAL VAL A . n A 1 247 THR 247 247 247 THR THR A . n A 1 248 ASP 248 248 248 ASP ASP A . n A 1 249 LYS 249 249 249 LYS LYS A . n A 1 250 ASP 250 250 250 ASP ASP A . n A 1 251 GLN 251 251 251 GLN GLN A . n A 1 252 PRO 252 252 252 PRO PRO A . n A 1 253 HIS 253 253 253 HIS HIS A . n A 1 254 THR 254 254 254 THR THR A . n A 1 255 PRO 255 255 255 PRO PRO A . n A 1 256 ALA 256 256 256 ALA ALA A . n A 1 257 TRP 257 257 257 TRP TRP A . n A 1 258 ASN 258 258 258 ASN ASN A . n A 1 259 ALA 259 259 259 ALA ALA A . n A 1 260 ALA 260 260 260 ALA ALA A . n A 1 261 TYR 261 261 261 TYR TYR A . n A 1 262 ARG 262 262 262 ARG ARG A . n A 1 263 ILE 263 263 263 ILE ILE A . n A 1 264 SER 264 264 264 SER SER A . n A 1 265 GLY 265 265 265 GLY GLY A . n A 1 266 GLY 266 266 266 GLY GLY A . n A 1 267 ASP 267 267 267 ASP ASP A . n A 1 268 PRO 268 268 268 PRO PRO A . n A 1 269 THR 269 269 269 THR THR A . n A 1 270 GLY 270 270 270 GLY GLY A . n A 1 271 ARG 271 271 271 ARG ARG A . n A 1 272 PHE 272 272 272 PHE PHE A . n A 1 273 ALA 273 273 273 ALA ALA A . n A 1 274 ILE 274 274 274 ILE ILE A . n A 1 275 LEU 275 275 275 LEU LEU A . n A 1 276 THR 276 276 276 THR THR A . n A 1 277 ASP 277 277 277 ASP ASP A . n A 1 278 PRO 278 278 278 PRO PRO A . n A 1 279 ASN 279 279 279 ASN ASN A . n A 1 280 SER 280 280 280 SER SER A . n A 1 281 ASN 281 281 281 ASN ASN A . n A 1 282 ASP 282 282 282 ASP ASP A . n A 1 283 GLY 283 283 283 GLY GLY A . n A 1 284 LEU 284 284 284 LEU LEU A . n A 1 285 VAL 285 285 285 VAL VAL A . n A 1 286 THR 286 286 286 THR THR A . n A 1 287 VAL 287 287 287 VAL VAL A . n A 1 288 VAL 288 288 288 VAL VAL A . n A 1 289 LYS 289 289 289 LYS LYS A . n A 1 290 PRO 290 290 290 PRO PRO A . n A 1 291 ILE 291 291 291 ILE ILE A . n A 1 292 ASP 292 292 292 ASP ASP A . n A 1 293 PHE 293 293 293 PHE PHE A . n A 1 294 GLU 294 294 294 GLU GLU A . n A 1 295 THR 295 295 295 THR THR A . n A 1 296 ASN 296 296 296 ASN ASN A . n A 1 297 ARG 297 297 297 ARG ARG A . n A 1 298 MET 298 298 298 MET MET A . n A 1 299 PHE 299 299 299 PHE PHE A . n A 1 300 VAL 300 300 300 VAL VAL A . n A 1 301 LEU 301 301 301 LEU LEU A . n A 1 302 THR 302 302 302 THR THR A . n A 1 303 VAL 303 303 303 VAL VAL A . n A 1 304 ALA 304 304 304 ALA ALA A . n A 1 305 ALA 305 305 305 ALA ALA A . n A 1 306 GLU 306 306 306 GLU GLU A . n A 1 307 ASN 307 307 307 ASN ASN A . n A 1 308 GLN 308 308 308 GLN GLN A . n A 1 309 VAL 309 309 309 VAL VAL A . n A 1 310 PRO 310 310 310 PRO PRO A . n A 1 311 LEU 311 311 311 LEU LEU A . n A 1 312 ALA 312 312 312 ALA ALA A . n A 1 313 LYS 313 313 313 LYS LYS A . n A 1 314 GLY 314 314 314 GLY GLY A . n A 1 315 ILE 315 315 315 ILE ILE A . n A 1 316 GLN 316 316 316 GLN GLN A . n A 1 317 HIS 317 317 317 HIS HIS A . n A 1 318 PRO 318 318 318 PRO PRO A . n A 1 319 PRO 319 319 319 PRO PRO A . n A 1 320 GLN 320 320 320 GLN GLN A . n A 1 321 SER 321 321 321 SER SER A . n A 1 322 THR 322 322 322 THR THR A . n A 1 323 ALA 323 323 323 ALA ALA A . n A 1 324 THR 324 324 324 THR THR A . n A 1 325 VAL 325 325 325 VAL VAL A . n A 1 326 SER 326 326 326 SER SER A . n A 1 327 VAL 327 327 327 VAL VAL A . n A 1 328 THR 328 328 328 THR THR A . n A 1 329 VAL 329 329 329 VAL VAL A . n A 1 330 ILE 330 330 330 ILE ILE A . n A 1 331 ASP 331 331 331 ASP ASP A . n A 1 332 VAL 332 332 332 VAL VAL A . n A 1 333 ASN 333 333 333 ASN ASN A . n A 1 334 GLU 334 334 334 GLU GLU A . n A 1 335 ASN 335 335 335 ASN ASN A . n A 1 336 PRO 336 336 336 PRO PRO A . n A 1 337 TYR 337 337 337 TYR TYR A . n A 1 338 PHE 338 338 338 PHE PHE A . n A 1 339 ALA 339 339 339 ALA ALA A . n A 1 340 PRO 340 340 340 PRO PRO A . n A 1 341 ASN 341 341 341 ASN ASN A . n A 1 342 PRO 342 342 342 PRO PRO A . n A 1 343 LYS 343 343 343 LYS LYS A . n A 1 344 ILE 344 344 344 ILE ILE A . n A 1 345 ILE 345 345 345 ILE ILE A . n A 1 346 ARG 346 346 346 ARG ARG A . n A 1 347 GLN 347 347 347 GLN GLN A . n A 1 348 GLU 348 348 348 GLU GLU A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 GLY 350 350 350 GLY GLY A . n A 1 351 LEU 351 351 351 LEU LEU A . n A 1 352 HIS 352 352 352 HIS HIS A . n A 1 353 ALA 353 353 353 ALA ALA A . n A 1 354 GLY 354 354 354 GLY GLY A . n A 1 355 THR 355 355 355 THR THR A . n A 1 356 MET 356 356 356 MET MET A . n A 1 357 LEU 357 357 357 LEU LEU A . n A 1 358 THR 358 358 358 THR THR A . n A 1 359 THR 359 359 359 THR THR A . n A 1 360 LEU 360 360 360 LEU LEU A . n A 1 361 THR 361 361 361 THR THR A . n A 1 362 ALA 362 362 362 ALA ALA A . n A 1 363 GLN 363 363 363 GLN GLN A . n A 1 364 ASP 364 364 364 ASP ASP A . n A 1 365 PRO 365 365 365 PRO PRO A . n A 1 366 ASP 366 366 366 ASP ASP A . n A 1 367 ARG 367 367 367 ARG ARG A . n A 1 368 TYR 368 368 368 TYR TYR A . n A 1 369 MET 369 369 369 MET MET A . n A 1 370 GLN 370 370 370 GLN GLN A . n A 1 371 GLN 371 371 371 GLN GLN A . n A 1 372 ASN 372 372 372 ASN ASN A . n A 1 373 ILE 373 373 373 ILE ILE A . n A 1 374 ARG 374 374 374 ARG ARG A . n A 1 375 TYR 375 375 375 TYR TYR A . n A 1 376 THR 376 376 376 THR THR A . n A 1 377 LYS 377 377 377 LYS LYS A . n A 1 378 LEU 378 378 378 LEU LEU A . n A 1 379 SER 379 379 379 SER SER A . n A 1 380 ASP 380 380 380 ASP ASP A . n A 1 381 PRO 381 381 381 PRO PRO A . n A 1 382 ALA 382 382 382 ALA ALA A . n A 1 383 ASN 383 383 383 ASN ASN A . n A 1 384 TRP 384 384 384 TRP TRP A . n A 1 385 LEU 385 385 385 LEU LEU A . n A 1 386 LYS 386 386 386 LYS LYS A . n A 1 387 ILE 387 387 387 ILE ILE A . n A 1 388 ASP 388 388 388 ASP ASP A . n A 1 389 PRO 389 389 389 PRO PRO A . n A 1 390 VAL 390 390 390 VAL VAL A . n A 1 391 ASN 391 391 391 ASN ASN A . n A 1 392 GLY 392 392 392 GLY GLY A . n A 1 393 GLN 393 393 393 GLN GLN A . n A 1 394 ILE 394 394 394 ILE ILE A . n A 1 395 THR 395 395 395 THR THR A . n A 1 396 THR 396 396 396 THR THR A . n A 1 397 ILE 397 397 397 ILE ILE A . n A 1 398 ALA 398 398 398 ALA ALA A . n A 1 399 VAL 399 399 399 VAL VAL A . n A 1 400 LEU 400 400 400 LEU LEU A . n A 1 401 ASP 401 401 401 ASP ASP A . n A 1 402 ARG 402 402 402 ARG ARG A . n A 1 403 GLU 403 403 403 GLU GLU A . n A 1 404 SER 404 404 404 SER SER A . n A 1 405 PRO 405 405 405 PRO PRO A . n A 1 406 ASN 406 406 406 ASN ASN A . n A 1 407 VAL 407 407 407 VAL VAL A . n A 1 408 LYS 408 408 408 LYS LYS A . n A 1 409 ASN 409 409 409 ASN ASN A . n A 1 410 ASN 410 410 410 ASN ASN A . n A 1 411 ILE 411 411 411 ILE ILE A . n A 1 412 TYR 412 412 412 TYR TYR A . n A 1 413 ASN 413 413 413 ASN ASN A . n A 1 414 ALA 414 414 414 ALA ALA A . n A 1 415 THR 415 415 415 THR THR A . n A 1 416 PHE 416 416 416 PHE PHE A . n A 1 417 LEU 417 417 417 LEU LEU A . n A 1 418 ALA 418 418 418 ALA ALA A . n A 1 419 SER 419 419 419 SER SER A . n A 1 420 ASP 420 420 420 ASP ASP A . n A 1 421 ASN 421 421 421 ASN ASN A . n A 1 422 GLY 422 422 422 GLY GLY A . n A 1 423 ILE 423 423 423 ILE ILE A . n A 1 424 PRO 424 424 424 PRO PRO A . n A 1 425 PRO 425 425 425 PRO PRO A . n A 1 426 MET 426 426 426 MET MET A . n A 1 427 SER 427 427 427 SER SER A . n A 1 428 GLY 428 428 428 GLY GLY A . n A 1 429 THR 429 429 429 THR THR A . n A 1 430 GLY 430 430 430 GLY GLY A . n A 1 431 THR 431 431 431 THR THR A . n A 1 432 LEU 432 432 432 LEU LEU A . n A 1 433 GLN 433 433 433 GLN GLN A . n A 1 434 ILE 434 434 434 ILE ILE A . n A 1 435 TYR 435 435 435 TYR TYR A . n A 1 436 LEU 436 436 436 LEU LEU A . n A 1 437 LEU 437 437 437 LEU LEU A . n A 1 438 ASP 438 438 438 ASP ASP A . n A 1 439 ILE 439 439 439 ILE ILE A . n A 1 440 ASN 440 440 440 ASN ASN A . n A 1 441 ASP 441 441 441 ASP ASP A . n A 1 442 ASN 442 442 442 ASN ASN A . n A 1 443 ALA 443 443 443 ALA ALA A . n A 1 444 PRO 444 444 444 PRO PRO A . n A 1 445 GLN 445 445 445 GLN GLN A . n A 1 446 VAL 446 446 446 VAL VAL A . n A 1 447 LEU 447 447 447 LEU LEU A . n A 1 448 PRO 448 448 448 PRO PRO A . n A 1 449 GLN 449 449 449 GLN GLN A . n A 1 450 GLU 450 450 450 GLU GLU A . n A 1 451 ALA 451 451 451 ALA ALA A . n A 1 452 GLU 452 452 452 GLU GLU A . n A 1 453 THR 453 453 453 THR THR A . n A 1 454 CYS 454 454 454 CYS CYS A . n A 1 455 GLU 455 455 455 GLU GLU A . n A 1 456 THR 456 456 456 THR THR A . n A 1 457 PRO 457 457 457 PRO PRO A . n A 1 458 GLU 458 458 458 GLU GLU A . n A 1 459 PRO 459 459 459 PRO PRO A . n A 1 460 ASN 460 460 460 ASN ASN A . n A 1 461 SER 461 461 461 SER SER A . n A 1 462 ILE 462 462 462 ILE ILE A . n A 1 463 ASN 463 463 463 ASN ASN A . n A 1 464 ILE 464 464 464 ILE ILE A . n A 1 465 THR 465 465 465 THR THR A . n A 1 466 ALA 466 466 466 ALA ALA A . n A 1 467 LEU 467 467 467 LEU LEU A . n A 1 468 ASP 468 468 468 ASP ASP A . n A 1 469 TYR 469 469 469 TYR TYR A . n A 1 470 ASP 470 470 470 ASP ASP A . n A 1 471 ILE 471 471 471 ILE ILE A . n A 1 472 ASP 472 472 472 ASP ASP A . n A 1 473 PRO 473 473 473 PRO PRO A . n A 1 474 ASN 474 474 474 ASN ASN A . n A 1 475 ALA 475 475 475 ALA ALA A . n A 1 476 GLY 476 476 476 GLY GLY A . n A 1 477 PRO 477 477 477 PRO PRO A . n A 1 478 PHE 478 478 478 PHE PHE A . n A 1 479 ALA 479 479 479 ALA ALA A . n A 1 480 PHE 480 480 480 PHE PHE A . n A 1 481 ASP 481 481 481 ASP ASP A . n A 1 482 LEU 482 482 482 LEU LEU A . n A 1 483 PRO 483 483 483 PRO PRO A . n A 1 484 LEU 484 484 484 LEU LEU A . n A 1 485 SER 485 485 485 SER SER A . n A 1 486 PRO 486 486 486 PRO PRO A . n A 1 487 VAL 487 487 487 VAL VAL A . n A 1 488 THR 488 488 488 THR THR A . n A 1 489 ILE 489 489 489 ILE ILE A . n A 1 490 LYS 490 490 490 LYS LYS A . n A 1 491 ARG 491 491 491 ARG ARG A . n A 1 492 ASN 492 492 492 ASN ASN A . n A 1 493 TRP 493 493 493 TRP TRP A . n A 1 494 THR 494 494 494 THR THR A . n A 1 495 ILE 495 495 495 ILE ILE A . n A 1 496 ASN 496 496 496 ASN ASN A . n A 1 497 ARG 497 497 497 ARG ARG A . n A 1 498 LEU 498 498 498 LEU LEU A . n A 1 499 ASN 499 499 499 ASN ASN A . n A 1 500 GLY 500 500 500 GLY GLY A . n A 1 501 ASP 501 501 501 ASP ASP A . n A 1 502 PHE 502 502 502 PHE PHE A . n A 1 503 ALA 503 503 503 ALA ALA A . n A 1 504 GLN 504 504 504 GLN GLN A . n A 1 505 LEU 505 505 505 LEU LEU A . n A 1 506 ASN 506 506 506 ASN ASN A . n A 1 507 LEU 507 507 507 LEU LEU A . n A 1 508 LYS 508 508 508 LYS LYS A . n A 1 509 ILE 509 509 509 ILE ILE A . n A 1 510 LYS 510 510 510 LYS LYS A . n A 1 511 PHE 511 511 511 PHE ALA A . n A 1 512 LEU 512 512 ? ? ? A . n A 1 513 GLU 513 513 513 GLU GLU A . n A 1 514 ALA 514 514 514 ALA ALA A . n A 1 515 GLY 515 515 515 GLY GLY A . n A 1 516 ILE 516 516 516 ILE ILE A . n A 1 517 TYR 517 517 517 TYR TYR A . n A 1 518 GLU 518 518 518 GLU GLU A . n A 1 519 VAL 519 519 519 VAL VAL A . n A 1 520 PRO 520 520 520 PRO PRO A . n A 1 521 ILE 521 521 521 ILE ILE A . n A 1 522 ILE 522 522 522 ILE ILE A . n A 1 523 ILE 523 523 523 ILE ILE A . n A 1 524 THR 524 524 524 THR THR A . n A 1 525 ASP 525 525 525 ASP ASP A . n A 1 526 SER 526 526 526 SER SER A . n A 1 527 GLY 527 527 527 GLY GLY A . n A 1 528 ASN 528 528 528 ASN ASN A . n A 1 529 PRO 529 529 529 PRO PRO A . n A 1 530 PRO 530 530 530 PRO PRO A . n A 1 531 LYS 531 531 531 LYS LYS A . n A 1 532 SER 532 532 532 SER SER A . n A 1 533 ASN 533 533 533 ASN ASN A . n A 1 534 ILE 534 534 534 ILE ILE A . n A 1 535 SER 535 535 535 SER SER A . n A 1 536 ILE 536 536 536 ILE ILE A . n A 1 537 LEU 537 537 537 LEU LEU A . n A 1 538 ARG 538 538 538 ARG ARG A . n A 1 539 VAL 539 539 539 VAL VAL A . n A 1 540 LYS 540 540 540 LYS ALA A . n A 1 541 VAL 541 541 541 VAL VAL A . n A 1 542 CYS 542 542 542 CYS CYS A . n A 1 543 GLN 543 543 ? ? ? A . n A 1 544 CYS 544 544 ? ? ? A . n A 1 545 ASP 545 545 ? ? ? A . n A 1 546 SER 546 546 ? ? ? A . n A 1 547 ASN 547 547 ? ? ? A . n A 1 548 GLY 548 548 ? ? ? A . n A 1 549 ASP 549 549 ? ? ? A . n A 1 550 CYS 550 550 ? ? ? A . n A 1 551 THR 551 551 ? ? ? A . n A 1 552 ASP 552 552 ? ? ? A . n A 1 553 VAL 553 553 ? ? ? A . n A 1 554 HIS 554 554 ? ? ? A . n A 1 555 HIS 555 555 ? ? ? A . n A 1 556 HIS 556 556 ? ? ? A . n A 1 557 HIS 557 557 ? ? ? A . n A 1 558 HIS 558 558 ? ? ? A . n A 1 559 HIS 559 559 ? ? ? A . n # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 166 A ASN 166 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 243 A ASN 243 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 413 A ASN 413 ? ASN 'GLYCOSYLATION SITE' 4 A ASN 114 A ASN 114 ? ASN 'GLYCOSYLATION SITE' 5 A ASN 492 A ASN 492 ? ASN 'GLYCOSYLATION SITE' 6 A THR 206 A THR 206 ? THR 'GLYCOSYLATION SITE' 7 A SER 427 A SER 427 ? SER 'GLYCOSYLATION SITE' 8 A THR 324 A THR 324 ? THR 'GLYCOSYLATION SITE' 9 A SER 326 A SER 326 ? SER 'GLYCOSYLATION SITE' 10 A THR 429 A THR 429 ? THR 'GLYCOSYLATION SITE' 11 A THR 322 A THR 322 ? THR 'GLYCOSYLATION SITE' 12 A THR 431 A THR 431 ? THR 'GLYCOSYLATION SITE' 13 A THR 208 A THR 208 ? THR 'GLYCOSYLATION SITE' 14 A THR 131 A THR 131 ? THR 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1,2 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA,BA,CA,DA # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 10690 ? 1 MORE -40 ? 1 'SSA (A^2)' 62670 ? # loop_ _pdbx_struct_oper_list.id _pdbx_struct_oper_list.type _pdbx_struct_oper_list.name _pdbx_struct_oper_list.symmetry_operation _pdbx_struct_oper_list.matrix[1][1] _pdbx_struct_oper_list.matrix[1][2] _pdbx_struct_oper_list.matrix[1][3] _pdbx_struct_oper_list.vector[1] _pdbx_struct_oper_list.matrix[2][1] _pdbx_struct_oper_list.matrix[2][2] _pdbx_struct_oper_list.matrix[2][3] _pdbx_struct_oper_list.vector[2] _pdbx_struct_oper_list.matrix[3][1] _pdbx_struct_oper_list.matrix[3][2] _pdbx_struct_oper_list.matrix[3][3] _pdbx_struct_oper_list.vector[3] 1 'identity operation' 1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 2 'crystal symmetry operation' 4_555 x,-y,-z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 OD1 ? A ASP 179 ? A ASP 179 ? 1_555 CA ? G CA . ? A CA 606 ? 1_555 OD1 ? A ASP 218 ? A ASP 218 ? 1_555 159.8 ? 2 OD1 ? A ASP 179 ? A ASP 179 ? 1_555 CA ? G CA . ? A CA 606 ? 1_555 OE1 ? A GLU 181 ? A GLU 181 ? 1_555 92.1 ? 3 OD1 ? A ASP 218 ? A ASP 218 ? 1_555 CA ? G CA . ? A CA 606 ? 1_555 OE1 ? A GLU 181 ? A GLU 181 ? 1_555 103.7 ? 4 OD1 ? A ASP 179 ? A ASP 179 ? 1_555 CA ? G CA . ? A CA 606 ? 1_555 OE2 ? A GLU 119 ? A GLU 119 ? 1_555 84.3 ? 5 OD1 ? A ASP 218 ? A ASP 218 ? 1_555 CA ? G CA . ? A CA 606 ? 1_555 OE2 ? A GLU 119 ? A GLU 119 ? 1_555 87.1 ? 6 OE1 ? A GLU 181 ? A GLU 181 ? 1_555 CA ? G CA . ? A CA 606 ? 1_555 OE2 ? A GLU 119 ? A GLU 119 ? 1_555 76.8 ? 7 OE1 ? A GLU 69 ? A GLU 69 ? 1_555 CA ? B CA . ? A CA 601 ? 1_555 OD2 ? A ASP 103 ? A ASP 103 ? 1_555 112.5 ? 8 OE1 ? A GLU 69 ? A GLU 69 ? 1_555 CA ? B CA . ? A CA 601 ? 1_555 OD1 ? A ASP 67 ? A ASP 67 ? 1_555 88.2 ? 9 OD2 ? A ASP 103 ? A ASP 103 ? 1_555 CA ? B CA . ? A CA 601 ? 1_555 OD1 ? A ASP 67 ? A ASP 67 ? 1_555 158.6 ? 10 OE1 ? A GLU 69 ? A GLU 69 ? 1_555 CA ? B CA . ? A CA 601 ? 1_555 OE1 ? A GLU 11 ? A GLU 11 ? 1_555 89.7 ? 11 OD2 ? A ASP 103 ? A ASP 103 ? 1_555 CA ? B CA . ? A CA 601 ? 1_555 OE1 ? A GLU 11 ? A GLU 11 ? 1_555 85.5 ? 12 OD1 ? A ASP 67 ? A ASP 67 ? 1_555 CA ? B CA . ? A CA 601 ? 1_555 OE1 ? A GLU 11 ? A GLU 11 ? 1_555 89.4 ? 13 O ? A ASN 219 ? A ASN 219 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 O ? A ALA 256 ? A ALA 256 ? 1_555 168.2 ? 14 O ? A ASN 219 ? A ASN 219 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD1 ? A ASN 217 ? A ASN 217 ? 1_555 95.2 ? 15 O ? A ALA 256 ? A ALA 256 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD1 ? A ASN 217 ? A ASN 217 ? 1_555 89.0 ? 16 O ? A ASN 219 ? A ASN 219 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD1 ? A ASN 307 ? A ASN 307 ? 1_555 103.2 ? 17 O ? A ALA 256 ? A ALA 256 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD1 ? A ASN 307 ? A ASN 307 ? 1_555 88.6 ? 18 OD1 ? A ASN 217 ? A ASN 217 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD1 ? A ASN 307 ? A ASN 307 ? 1_555 74.7 ? 19 O ? A ASN 219 ? A ASN 219 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD2 ? A ASP 250 ? A ASP 250 ? 1_555 95.9 ? 20 O ? A ALA 256 ? A ALA 256 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD2 ? A ASP 250 ? A ASP 250 ? 1_555 74.8 ? 21 OD1 ? A ASN 217 ? A ASN 217 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD2 ? A ASP 250 ? A ASP 250 ? 1_555 73.4 ? 22 OD1 ? A ASN 307 ? A ASN 307 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD2 ? A ASP 250 ? A ASP 250 ? 1_555 144.0 ? 23 O ? A ASN 219 ? A ASN 219 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD2 ? A ASP 248 ? A ASP 248 ? 1_555 99.2 ? 24 O ? A ALA 256 ? A ALA 256 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD2 ? A ASP 248 ? A ASP 248 ? 1_555 82.3 ? 25 OD1 ? A ASN 217 ? A ASN 217 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD2 ? A ASP 248 ? A ASP 248 ? 1_555 149.5 ? 26 OD1 ? A ASN 307 ? A ASN 307 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD2 ? A ASP 248 ? A ASP 248 ? 1_555 75.9 ? 27 OD2 ? A ASP 250 ? A ASP 250 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD2 ? A ASP 248 ? A ASP 248 ? 1_555 130.9 ? 28 O ? A ASN 219 ? A ASN 219 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD1 ? A ASP 248 ? A ASP 248 ? 1_555 75.9 ? 29 O ? A ALA 256 ? A ALA 256 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD1 ? A ASP 248 ? A ASP 248 ? 1_555 97.1 ? 30 OD1 ? A ASN 217 ? A ASN 217 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD1 ? A ASP 248 ? A ASP 248 ? 1_555 163.2 ? 31 OD1 ? A ASN 307 ? A ASN 307 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD1 ? A ASP 248 ? A ASP 248 ? 1_555 120.9 ? 32 OD2 ? A ASP 250 ? A ASP 250 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD1 ? A ASP 248 ? A ASP 248 ? 1_555 93.0 ? 33 OD2 ? A ASP 248 ? A ASP 248 ? 1_555 CA ? F CA . ? A CA 605 ? 1_555 OD1 ? A ASP 248 ? A ASP 248 ? 1_555 47.3 ? 34 OE2 ? A GLU 294 ? A GLU 294 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OE2 ? A GLU 334 ? A GLU 334 ? 1_555 126.3 ? 35 OE2 ? A GLU 294 ? A GLU 294 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OD1 ? A ASP 331 ? A ASP 331 ? 1_555 90.3 ? 36 OE2 ? A GLU 334 ? A GLU 334 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OD1 ? A ASP 331 ? A ASP 331 ? 1_555 123.3 ? 37 OE2 ? A GLU 294 ? A GLU 294 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 O ? A VAL 332 ? A VAL 332 ? 1_555 162.4 ? 38 OE2 ? A GLU 334 ? A GLU 334 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 O ? A VAL 332 ? A VAL 332 ? 1_555 70.0 ? 39 OD1 ? A ASP 331 ? A ASP 331 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 O ? A VAL 332 ? A VAL 332 ? 1_555 73.6 ? 40 OE2 ? A GLU 294 ? A GLU 294 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OE2 ? A GLU 234 ? A GLU 234 ? 1_555 92.6 ? 41 OE2 ? A GLU 334 ? A GLU 334 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OE2 ? A GLU 234 ? A GLU 234 ? 1_555 66.8 ? 42 OD1 ? A ASP 331 ? A ASP 331 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OE2 ? A GLU 234 ? A GLU 234 ? 1_555 70.3 ? 43 O ? A VAL 332 ? A VAL 332 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OE2 ? A GLU 234 ? A GLU 234 ? 1_555 88.4 ? 44 OE2 ? A GLU 294 ? A GLU 294 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OE1 ? A GLU 234 ? A GLU 234 ? 1_555 68.7 ? 45 OE2 ? A GLU 334 ? A GLU 334 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OE1 ? A GLU 234 ? A GLU 234 ? 1_555 63.4 ? 46 OD1 ? A ASP 331 ? A ASP 331 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OE1 ? A GLU 234 ? A GLU 234 ? 1_555 104.1 ? 47 O ? A VAL 332 ? A VAL 332 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OE1 ? A GLU 234 ? A GLU 234 ? 1_555 121.3 ? 48 OE2 ? A GLU 234 ? A GLU 234 ? 1_555 CA ? I CA . ? A CA 608 ? 1_555 OE1 ? A GLU 234 ? A GLU 234 ? 1_555 41.7 ? 49 OE1 ? A GLU 234 ? A GLU 234 ? 1_555 CA ? H CA . ? A CA 607 ? 1_555 OE1 ? A GLU 294 ? A GLU 294 ? 1_555 72.8 ? 50 OE1 ? A GLU 234 ? A GLU 234 ? 1_555 CA ? H CA . ? A CA 607 ? 1_555 OE1 ? A GLU 334 ? A GLU 334 ? 1_555 89.2 ? 51 OE1 ? A GLU 294 ? A GLU 294 ? 1_555 CA ? H CA . ? A CA 607 ? 1_555 OE1 ? A GLU 334 ? A GLU 334 ? 1_555 103.8 ? 52 OE1 ? A GLU 234 ? A GLU 234 ? 1_555 CA ? H CA . ? A CA 607 ? 1_555 OD1 ? A ASP 292 ? A ASP 292 ? 1_555 117.9 ? 53 OE1 ? A GLU 294 ? A GLU 294 ? 1_555 CA ? H CA . ? A CA 607 ? 1_555 OD1 ? A ASP 292 ? A ASP 292 ? 1_555 83.7 ? 54 OE1 ? A GLU 334 ? A GLU 334 ? 1_555 CA ? H CA . ? A CA 607 ? 1_555 OD1 ? A ASP 292 ? A ASP 292 ? 1_555 152.8 ? 55 OD1 ? A ASP 525 ? A ASP 525 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 O ? A ASN 442 ? A ASN 442 ? 1_555 97.7 ? 56 OD1 ? A ASP 525 ? A ASP 525 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD1 ? A ASN 440 ? A ASN 440 ? 1_555 81.9 ? 57 O ? A ASN 442 ? A ASN 442 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD1 ? A ASN 440 ? A ASN 440 ? 1_555 113.8 ? 58 OD1 ? A ASP 525 ? A ASP 525 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD1 ? A ASP 470 ? A ASP 470 ? 1_555 162.3 ? 59 O ? A ASN 442 ? A ASN 442 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD1 ? A ASP 470 ? A ASP 470 ? 1_555 99.4 ? 60 OD1 ? A ASN 440 ? A ASN 440 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD1 ? A ASP 470 ? A ASP 470 ? 1_555 86.9 ? 61 OD1 ? A ASP 525 ? A ASP 525 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD2 ? A ASP 468 ? A ASP 468 ? 1_555 70.7 ? 62 O ? A ASN 442 ? A ASN 442 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD2 ? A ASP 468 ? A ASP 468 ? 1_555 112.3 ? 63 OD1 ? A ASN 440 ? A ASN 440 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD2 ? A ASP 468 ? A ASP 468 ? 1_555 128.6 ? 64 OD1 ? A ASP 470 ? A ASP 470 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD2 ? A ASP 468 ? A ASP 468 ? 1_555 106.8 ? 65 OD1 ? A ASP 525 ? A ASP 525 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD1 ? A ASP 468 ? A ASP 468 ? 1_555 107.2 ? 66 O ? A ASN 442 ? A ASN 442 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD1 ? A ASP 468 ? A ASP 468 ? 1_555 80.3 ? 67 OD1 ? A ASN 440 ? A ASN 440 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD1 ? A ASP 468 ? A ASP 468 ? 1_555 162.6 ? 68 OD1 ? A ASP 470 ? A ASP 470 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD1 ? A ASP 468 ? A ASP 468 ? 1_555 80.5 ? 69 OD2 ? A ASP 468 ? A ASP 468 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 OD1 ? A ASP 468 ? A ASP 468 ? 1_555 46.3 ? 70 OD1 ? A ASP 525 ? A ASP 525 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 O ? A ASN 474 ? A ASN 474 ? 1_555 76.6 ? 71 O ? A ASN 442 ? A ASN 442 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 O ? A ASN 474 ? A ASN 474 ? 1_555 170.4 ? 72 OD1 ? A ASN 440 ? A ASN 440 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 O ? A ASN 474 ? A ASN 474 ? 1_555 73.3 ? 73 OD1 ? A ASP 470 ? A ASP 470 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 O ? A ASN 474 ? A ASN 474 ? 1_555 87.1 ? 74 OD2 ? A ASP 468 ? A ASP 468 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 O ? A ASN 474 ? A ASN 474 ? 1_555 58.7 ? 75 OD1 ? A ASP 468 ? A ASP 468 ? 1_555 CA ? M CA . ? A CA 612 ? 1_555 O ? A ASN 474 ? A ASN 474 ? 1_555 94.0 ? 76 OD1 ? A ASN 102 ? A ASN 102 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 83.6 ? 77 OD1 ? A ASN 102 ? A ASN 102 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD2 ? A ASP 194 ? A ASP 194 ? 1_555 71.2 ? 78 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD2 ? A ASP 194 ? A ASP 194 ? 1_555 149.5 ? 79 OD1 ? A ASN 102 ? A ASN 102 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD1 ? A ASP 134 ? A ASP 134 ? 1_555 153.4 ? 80 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD1 ? A ASP 134 ? A ASP 134 ? 1_555 113.7 ? 81 OD2 ? A ASP 194 ? A ASP 194 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD1 ? A ASP 134 ? A ASP 134 ? 1_555 96.0 ? 82 OD1 ? A ASN 102 ? A ASN 102 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 O ? A ASN 104 ? A ASN 104 ? 1_555 111.0 ? 83 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 O ? A ASN 104 ? A ASN 104 ? 1_555 78.1 ? 84 OD2 ? A ASP 194 ? A ASP 194 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 O ? A ASN 104 ? A ASN 104 ? 1_555 94.6 ? 85 OD1 ? A ASP 134 ? A ASP 134 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 O ? A ASN 104 ? A ASN 104 ? 1_555 92.8 ? 86 OD1 ? A ASN 102 ? A ASN 102 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 O ? A ASN 142 ? A ASN 142 ? 1_555 79.4 ? 87 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 O ? A ASN 142 ? A ASN 142 ? 1_555 105.3 ? 88 OD2 ? A ASP 194 ? A ASP 194 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 O ? A ASN 142 ? A ASN 142 ? 1_555 87.2 ? 89 OD1 ? A ASP 134 ? A ASP 134 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 O ? A ASN 142 ? A ASN 142 ? 1_555 76.6 ? 90 O ? A ASN 104 ? A ASN 104 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 O ? A ASN 142 ? A ASN 142 ? 1_555 169.4 ? 91 OD1 ? A ASN 102 ? A ASN 102 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD2 ? A ASP 134 ? A ASP 134 ? 1_555 145.3 ? 92 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD2 ? A ASP 134 ? A ASP 134 ? 1_555 65.9 ? 93 OD2 ? A ASP 194 ? A ASP 194 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD2 ? A ASP 134 ? A ASP 134 ? 1_555 142.6 ? 94 OD1 ? A ASP 134 ? A ASP 134 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD2 ? A ASP 134 ? A ASP 134 ? 1_555 48.0 ? 95 O ? A ASN 104 ? A ASN 104 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD2 ? A ASP 134 ? A ASP 134 ? 1_555 79.9 ? 96 O ? A ASN 142 ? A ASN 142 ? 1_555 CA ? D CA . ? A CA 603 ? 1_555 OD2 ? A ASP 134 ? A ASP 134 ? 1_555 92.3 ? 97 OE2 ? A GLU 11 ? A GLU 11 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OD1 ? A ASP 103 ? A ASP 103 ? 1_555 82.6 ? 98 OE2 ? A GLU 11 ? A GLU 11 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 O ? A MET 101 ? A MET 101 ? 1_555 82.9 ? 99 OD1 ? A ASP 103 ? A ASP 103 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 O ? A MET 101 ? A MET 101 ? 1_555 76.8 ? 100 OE2 ? A GLU 11 ? A GLU 11 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OD1 ? A ASP 136 ? A ASP 136 ? 1_555 165.0 ? 101 OD1 ? A ASP 103 ? A ASP 103 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OD1 ? A ASP 136 ? A ASP 136 ? 1_555 85.8 ? 102 O ? A MET 101 ? A MET 101 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OD1 ? A ASP 136 ? A ASP 136 ? 1_555 85.2 ? 103 OE2 ? A GLU 11 ? A GLU 11 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OD1 ? A ASP 100 ? A ASP 100 ? 1_555 83.5 ? 104 OD1 ? A ASP 103 ? A ASP 103 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OD1 ? A ASP 100 ? A ASP 100 ? 1_555 156.6 ? 105 O ? A MET 101 ? A MET 101 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OD1 ? A ASP 100 ? A ASP 100 ? 1_555 82.9 ? 106 OD1 ? A ASP 136 ? A ASP 136 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OD1 ? A ASP 100 ? A ASP 100 ? 1_555 104.1 ? 107 OE2 ? A GLU 11 ? A GLU 11 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OE2 ? A GLU 69 ? A GLU 69 ? 1_555 103.5 ? 108 OD1 ? A ASP 103 ? A ASP 103 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OE2 ? A GLU 69 ? A GLU 69 ? 1_555 127.4 ? 109 O ? A MET 101 ? A MET 101 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OE2 ? A GLU 69 ? A GLU 69 ? 1_555 155.2 ? 110 OD1 ? A ASP 136 ? A ASP 136 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OE2 ? A GLU 69 ? A GLU 69 ? 1_555 91.1 ? 111 OD1 ? A ASP 100 ? A ASP 100 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OE2 ? A GLU 69 ? A GLU 69 ? 1_555 74.3 ? 112 OE2 ? A GLU 11 ? A GLU 11 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OE1 ? A GLU 69 ? A GLU 69 ? 1_555 81.6 ? 113 OD1 ? A ASP 103 ? A ASP 103 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OE1 ? A GLU 69 ? A GLU 69 ? 1_555 80.5 ? 114 O ? A MET 101 ? A MET 101 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OE1 ? A GLU 69 ? A GLU 69 ? 1_555 153.9 ? 115 OD1 ? A ASP 136 ? A ASP 136 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OE1 ? A GLU 69 ? A GLU 69 ? 1_555 105.9 ? 116 OD1 ? A ASP 100 ? A ASP 100 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OE1 ? A GLU 69 ? A GLU 69 ? 1_555 115.9 ? 117 OE2 ? A GLU 69 ? A GLU 69 ? 1_555 CA ? C CA . ? A CA 602 ? 1_555 OE1 ? A GLU 69 ? A GLU 69 ? 1_555 50.1 ? 118 OD2 ? A ASP 218 ? A ASP 218 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OD2 ? A ASP 215 ? A ASP 215 ? 1_555 148.3 ? 119 OD2 ? A ASP 218 ? A ASP 218 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OE2 ? A GLU 181 ? A GLU 181 ? 1_555 117.9 ? 120 OD2 ? A ASP 215 ? A ASP 215 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OE2 ? A GLU 181 ? A GLU 181 ? 1_555 87.3 ? 121 OD2 ? A ASP 218 ? A ASP 218 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OE1 ? A GLU 119 ? A GLU 119 ? 1_555 88.0 ? 122 OD2 ? A ASP 215 ? A ASP 215 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OE1 ? A GLU 119 ? A GLU 119 ? 1_555 95.1 ? 123 OE2 ? A GLU 181 ? A GLU 181 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OE1 ? A GLU 119 ? A GLU 119 ? 1_555 121.1 ? 124 OD2 ? A ASP 218 ? A ASP 218 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 O ? A VAL 216 ? A VAL 216 ? 1_555 73.9 ? 125 OD2 ? A ASP 215 ? A ASP 215 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 O ? A VAL 216 ? A VAL 216 ? 1_555 75.2 ? 126 OE2 ? A GLU 181 ? A GLU 181 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 O ? A VAL 216 ? A VAL 216 ? 1_555 151.8 ? 127 OE1 ? A GLU 119 ? A GLU 119 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 O ? A VAL 216 ? A VAL 216 ? 1_555 83.0 ? 128 OD2 ? A ASP 218 ? A ASP 218 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OD1 ? A ASP 250 ? A ASP 250 ? 1_555 66.1 ? 129 OD2 ? A ASP 215 ? A ASP 215 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OD1 ? A ASP 250 ? A ASP 250 ? 1_555 104.4 ? 130 OE2 ? A GLU 181 ? A GLU 181 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OD1 ? A ASP 250 ? A ASP 250 ? 1_555 78.0 ? 131 OE1 ? A GLU 119 ? A GLU 119 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OD1 ? A ASP 250 ? A ASP 250 ? 1_555 153.7 ? 132 O ? A VAL 216 ? A VAL 216 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OD1 ? A ASP 250 ? A ASP 250 ? 1_555 85.1 ? 133 OD2 ? A ASP 218 ? A ASP 218 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OE1 ? A GLU 181 ? A GLU 181 ? 1_555 83.0 ? 134 OD2 ? A ASP 215 ? A ASP 215 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OE1 ? A GLU 181 ? A GLU 181 ? 1_555 128.2 ? 135 OE2 ? A GLU 181 ? A GLU 181 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OE1 ? A GLU 181 ? A GLU 181 ? 1_555 46.0 ? 136 OE1 ? A GLU 119 ? A GLU 119 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OE1 ? A GLU 181 ? A GLU 181 ? 1_555 93.3 ? 137 O ? A VAL 216 ? A VAL 216 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OE1 ? A GLU 181 ? A GLU 181 ? 1_555 156.6 ? 138 OD1 ? A ASP 250 ? A ASP 250 ? 1_555 CA ? E CA . ? A CA 604 ? 1_555 OE1 ? A GLU 181 ? A GLU 181 ? 1_555 88.4 ? 139 OD1 ? A ASP 438 ? A ASP 438 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 O ? A ILE 439 ? A ILE 439 ? 1_555 85.2 ? 140 OD1 ? A ASP 438 ? A ASP 438 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE1 ? A GLU 349 ? A GLU 349 ? 1_555 106.2 ? 141 O ? A ILE 439 ? A ILE 439 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE1 ? A GLU 349 ? A GLU 349 ? 1_555 111.5 ? 142 OD1 ? A ASP 438 ? A ASP 438 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OD2 ? A ASP 441 ? A ASP 441 ? 1_555 153.3 ? 143 O ? A ILE 439 ? A ILE 439 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OD2 ? A ASP 441 ? A ASP 441 ? 1_555 74.2 ? 144 OE1 ? A GLU 349 ? A GLU 349 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OD2 ? A ASP 441 ? A ASP 441 ? 1_555 97.1 ? 145 OD1 ? A ASP 438 ? A ASP 438 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE1 ? A GLU 403 ? A GLU 403 ? 1_555 124.1 ? 146 O ? A ILE 439 ? A ILE 439 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE1 ? A GLU 403 ? A GLU 403 ? 1_555 146.2 ? 147 OE1 ? A GLU 349 ? A GLU 349 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE1 ? A GLU 403 ? A GLU 403 ? 1_555 78.8 ? 148 OD2 ? A ASP 441 ? A ASP 441 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE1 ? A GLU 403 ? A GLU 403 ? 1_555 72.6 ? 149 OD1 ? A ASP 438 ? A ASP 438 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OD2 ? A ASP 470 ? A ASP 470 ? 1_555 71.2 ? 150 O ? A ILE 439 ? A ILE 439 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OD2 ? A ASP 470 ? A ASP 470 ? 1_555 93.8 ? 151 OE1 ? A GLU 349 ? A GLU 349 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OD2 ? A ASP 470 ? A ASP 470 ? 1_555 154.4 ? 152 OD2 ? A ASP 441 ? A ASP 441 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OD2 ? A ASP 470 ? A ASP 470 ? 1_555 93.1 ? 153 OE1 ? A GLU 403 ? A GLU 403 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OD2 ? A ASP 470 ? A ASP 470 ? 1_555 82.1 ? 154 OD1 ? A ASP 438 ? A ASP 438 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE2 ? A GLU 403 ? A GLU 403 ? 1_555 79.2 ? 155 O ? A ILE 439 ? A ILE 439 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE2 ? A GLU 403 ? A GLU 403 ? 1_555 154.2 ? 156 OE1 ? A GLU 349 ? A GLU 349 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE2 ? A GLU 403 ? A GLU 403 ? 1_555 92.7 ? 157 OD2 ? A ASP 441 ? A ASP 441 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE2 ? A GLU 403 ? A GLU 403 ? 1_555 113.0 ? 158 OE1 ? A GLU 403 ? A GLU 403 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE2 ? A GLU 403 ? A GLU 403 ? 1_555 44.9 ? 159 OD2 ? A ASP 470 ? A ASP 470 ? 1_555 CA ? K CA . ? A CA 610 ? 1_555 OE2 ? A GLU 403 ? A GLU 403 ? 1_555 61.7 ? 160 OD1 ? A ASP 401 ? A ASP 401 ? 1_555 CA ? L CA . ? A CA 611 ? 1_555 OE2 ? A GLU 349 ? A GLU 349 ? 1_555 91.8 ? 161 OD1 ? A ASP 401 ? A ASP 401 ? 1_555 CA ? L CA . ? A CA 611 ? 1_555 OE1 ? A GLU 403 ? A GLU 403 ? 1_555 97.9 ? 162 OE2 ? A GLU 349 ? A GLU 349 ? 1_555 CA ? L CA . ? A CA 611 ? 1_555 OE1 ? A GLU 403 ? A GLU 403 ? 1_555 69.7 ? 163 OD1 ? A ASP 401 ? A ASP 401 ? 1_555 CA ? L CA . ? A CA 611 ? 1_555 OD1 ? A ASP 441 ? A ASP 441 ? 1_555 166.1 ? 164 OE2 ? A GLU 349 ? A GLU 349 ? 1_555 CA ? L CA . ? A CA 611 ? 1_555 OD1 ? A ASP 441 ? A ASP 441 ? 1_555 97.0 ? 165 OE1 ? A GLU 403 ? A GLU 403 ? 1_555 CA ? L CA . ? A CA 611 ? 1_555 OD1 ? A ASP 441 ? A ASP 441 ? 1_555 95.3 ? 166 OD1 ? A ASN 333 ? A ASN 333 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 O ? A GLU 334 ? A GLU 334 ? 1_555 98.2 ? 167 OD1 ? A ASN 333 ? A ASN 333 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OD2 ? A ASP 420 ? A ASP 420 ? 1_555 81.1 ? 168 O ? A GLU 334 ? A GLU 334 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OD2 ? A ASP 420 ? A ASP 420 ? 1_555 73.2 ? 169 OD1 ? A ASN 333 ? A ASN 333 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OD2 ? A ASP 364 ? A ASP 364 ? 1_555 145.9 ? 170 O ? A GLU 334 ? A GLU 334 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OD2 ? A ASP 364 ? A ASP 364 ? 1_555 108.7 ? 171 OD2 ? A ASP 420 ? A ASP 420 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OD2 ? A ASP 364 ? A ASP 364 ? 1_555 126.0 ? 172 OD1 ? A ASN 333 ? A ASN 333 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OE1 ? A GLN 371 ? A GLN 371 ? 1_555 85.2 ? 173 O ? A GLU 334 ? A GLU 334 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OE1 ? A GLN 371 ? A GLN 371 ? 1_555 165.7 ? 174 OD2 ? A ASP 420 ? A ASP 420 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OE1 ? A GLN 371 ? A GLN 371 ? 1_555 93.8 ? 175 OD2 ? A ASP 364 ? A ASP 364 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OE1 ? A GLN 371 ? A GLN 371 ? 1_555 73.9 ? 176 OD1 ? A ASN 333 ? A ASN 333 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OD1 ? A ASP 364 ? A ASP 364 ? 1_555 169.0 ? 177 O ? A GLU 334 ? A GLU 334 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OD1 ? A ASP 364 ? A ASP 364 ? 1_555 71.1 ? 178 OD2 ? A ASP 420 ? A ASP 420 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OD1 ? A ASP 364 ? A ASP 364 ? 1_555 93.1 ? 179 OD2 ? A ASP 364 ? A ASP 364 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OD1 ? A ASP 364 ? A ASP 364 ? 1_555 44.3 ? 180 OE1 ? A GLN 371 ? A GLN 371 ? 1_555 CA ? J CA . ? A CA 609 ? 1_555 OD1 ? A ASP 364 ? A ASP 364 ? 1_555 104.6 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2011-02-23 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal ADSC 'data collection' Quantum ? 1 MOLREP phasing . ? 2 PHENIX refinement '(phenix.refine: 1.6_289)' ? 3 DENZO 'data reduction' . ? 4 SCALEPACK 'data scaling' . ? 5 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 N A ASP 501 ? ? CA A ASP 501 ? ? CB A ASP 501 ? ? 90.62 110.60 -19.98 1.80 N 2 1 N A ASP 501 ? ? CA A ASP 501 ? ? C A ASP 501 ? ? 134.03 111.00 23.03 2.70 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASN A 31 ? ? -142.83 -28.10 2 1 ALA A 43 ? ? -110.89 -70.57 3 1 ASN A 160 ? ? -118.93 68.47 4 1 ASN A 166 ? ? -57.44 -9.61 5 1 GLU A 181 ? ? -68.68 3.06 6 1 LYS A 182 ? ? -121.97 -60.84 7 1 ASP A 194 ? ? -77.97 -166.79 8 1 VAL A 241 ? ? -90.57 -60.14 9 1 ASP A 250 ? ? -69.86 -171.57 10 1 PRO A 310 ? ? -46.07 150.86 11 1 LYS A 343 ? ? -47.97 107.21 12 1 GLU A 349 ? ? -73.04 -73.67 13 1 ASP A 366 ? ? -64.97 86.94 14 1 LEU A 378 ? ? -127.41 -84.31 15 1 PRO A 381 ? ? -62.32 4.89 16 1 PRO A 405 ? ? -69.15 6.65 17 1 ASN A 410 ? ? -48.13 -19.75 18 1 PRO A 457 ? ? -69.36 49.91 19 1 ALA A 475 ? ? -128.95 -76.02 20 1 LEU A 498 ? ? -100.31 -60.67 21 1 ASN A 499 ? ? -136.44 -63.51 22 1 ASP A 501 ? ? -56.36 2.95 # loop_ _pdbx_validate_chiral.id _pdbx_validate_chiral.PDB_model_num _pdbx_validate_chiral.auth_atom_id _pdbx_validate_chiral.label_alt_id _pdbx_validate_chiral.auth_asym_id _pdbx_validate_chiral.auth_comp_id _pdbx_validate_chiral.auth_seq_id _pdbx_validate_chiral.PDB_ins_code _pdbx_validate_chiral.details _pdbx_validate_chiral.omega 1 1 C1 ? A MAN 701 ? 'WRONG HAND' . 2 1 C1 ? A MAN 702 ? PLANAR . 3 1 C1 ? A MAN 706 ? 'WRONG HAND' . 4 1 C1 ? A MAN 709 ? 'WRONG HAND' . 5 1 C1 ? A NAG 801 ? PLANAR . 6 1 C1 ? A NAG 804 ? PLANAR . 7 1 C1 ? A NAG 805 ? 'WRONG HAND' . 8 1 C1 ? A NAG 807 ? 'WRONG HAND' . # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A LYS 30 ? CD ? A LYS 30 CD 2 1 Y 1 A LYS 30 ? CE ? A LYS 30 CE 3 1 Y 1 A LYS 30 ? NZ ? A LYS 30 NZ 4 1 Y 1 A PHE 511 ? CG ? A PHE 511 CG 5 1 Y 1 A PHE 511 ? CD1 ? A PHE 511 CD1 6 1 Y 1 A PHE 511 ? CD2 ? A PHE 511 CD2 7 1 Y 1 A PHE 511 ? CE1 ? A PHE 511 CE1 8 1 Y 1 A PHE 511 ? CE2 ? A PHE 511 CE2 9 1 Y 1 A PHE 511 ? CZ ? A PHE 511 CZ 10 1 Y 1 A LYS 540 ? CG ? A LYS 540 CG 11 1 Y 1 A LYS 540 ? CD ? A LYS 540 CD 12 1 Y 1 A LYS 540 ? CE ? A LYS 540 CE 13 1 Y 1 A LYS 540 ? NZ ? A LYS 540 NZ # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A LEU 512 ? A LEU 512 2 1 Y 1 A GLN 543 ? A GLN 543 3 1 Y 1 A CYS 544 ? A CYS 544 4 1 Y 1 A ASP 545 ? A ASP 545 5 1 Y 1 A SER 546 ? A SER 546 6 1 Y 1 A ASN 547 ? A ASN 547 7 1 Y 1 A GLY 548 ? A GLY 548 8 1 Y 1 A ASP 549 ? A ASP 549 9 1 Y 1 A CYS 550 ? A CYS 550 10 1 Y 1 A THR 551 ? A THR 551 11 1 Y 1 A ASP 552 ? A ASP 552 12 1 Y 1 A VAL 553 ? A VAL 553 13 1 Y 1 A HIS 554 ? A HIS 554 14 1 Y 1 A HIS 555 ? A HIS 555 15 1 Y 1 A HIS 556 ? A HIS 556 16 1 Y 1 A HIS 557 ? A HIS 557 17 1 Y 1 A HIS 558 ? A HIS 558 18 1 Y 1 A HIS 559 ? A HIS 559 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 'CALCIUM ION' CA 3 ALPHA-D-MANNOSE MAN 4 N-ACETYL-D-GLUCOSAMINE NAG 5 water HOH # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 CA 1 601 601 CA CA A . C 2 CA 1 602 602 CA CA A . D 2 CA 1 603 603 CA CA A . E 2 CA 1 604 604 CA CA A . F 2 CA 1 605 605 CA CA A . G 2 CA 1 606 606 CA CA A . H 2 CA 1 607 607 CA CA A . I 2 CA 1 608 608 CA CA A . J 2 CA 1 609 609 CA CA A . K 2 CA 1 610 610 CA CA A . L 2 CA 1 611 611 CA CA A . M 2 CA 1 612 612 CA CA A . N 3 MAN 1 701 701 MAN MAN A . O 3 MAN 1 702 702 MAN MAN A . P 3 MAN 1 703 703 MAN MAN A . Q 3 MAN 1 705 705 MAN MAN A . R 3 MAN 1 706 706 MAN MAN A . S 3 MAN 1 707 707 MAN MAN A . T 3 MAN 1 708 708 MAN MAN A . U 3 MAN 1 709 709 MAN MAN A . V 3 MAN 1 710 710 MAN MAN A . W 4 NAG 1 801 801 NAG NAG A . X 4 NAG 1 802 802 NAG NAG A . Y 4 NAG 2 803 803 NAG NAG A . Z 4 NAG 1 804 804 NAG NAG A . AA 4 NAG 1 805 805 NAG NAG A . BA 4 NAG 2 806 806 NAG NAG A . CA 4 NAG 1 807 807 NAG NAG A . DA 5 HOH 1 559 1 HOH HOH A . DA 5 HOH 2 560 2 HOH HOH A . DA 5 HOH 3 561 3 HOH HOH A . DA 5 HOH 4 562 4 HOH HOH A . DA 5 HOH 5 563 5 HOH HOH A . DA 5 HOH 6 564 6 HOH HOH A . DA 5 HOH 7 565 7 HOH HOH A . DA 5 HOH 8 566 8 HOH HOH A . DA 5 HOH 9 567 9 HOH HOH A . DA 5 HOH 10 568 10 HOH HOH A . DA 5 HOH 11 569 11 HOH HOH A . DA 5 HOH 12 570 12 HOH HOH A . DA 5 HOH 13 571 13 HOH HOH A . DA 5 HOH 14 572 14 HOH HOH A . DA 5 HOH 15 573 15 HOH HOH A . DA 5 HOH 16 574 16 HOH HOH A . DA 5 HOH 17 575 17 HOH HOH A . DA 5 HOH 18 576 18 HOH HOH A . DA 5 HOH 19 577 19 HOH HOH A . DA 5 HOH 20 578 20 HOH HOH A . DA 5 HOH 21 579 21 HOH HOH A . DA 5 HOH 22 580 22 HOH HOH A . DA 5 HOH 23 581 23 HOH HOH A . DA 5 HOH 24 582 24 HOH HOH A . DA 5 HOH 25 583 25 HOH HOH A . DA 5 HOH 26 584 26 HOH HOH A . DA 5 HOH 27 585 27 HOH HOH A . DA 5 HOH 28 586 28 HOH HOH A . DA 5 HOH 29 587 29 HOH HOH A . DA 5 HOH 30 588 30 HOH HOH A . DA 5 HOH 31 589 31 HOH HOH A . DA 5 HOH 32 590 32 HOH HOH A . DA 5 HOH 33 591 33 HOH HOH A . DA 5 HOH 34 592 34 HOH HOH A . DA 5 HOH 35 593 35 HOH HOH A . DA 5 HOH 36 594 36 HOH HOH A . DA 5 HOH 37 595 37 HOH HOH A . DA 5 HOH 38 596 38 HOH HOH A . DA 5 HOH 39 597 39 HOH HOH A . DA 5 HOH 40 598 40 HOH HOH A . DA 5 HOH 41 599 41 HOH HOH A . DA 5 HOH 42 600 42 HOH HOH A . DA 5 HOH 43 613 43 HOH HOH A . DA 5 HOH 44 614 44 HOH HOH A . DA 5 HOH 45 615 45 HOH HOH A . DA 5 HOH 46 616 46 HOH HOH A . DA 5 HOH 47 617 47 HOH HOH A . DA 5 HOH 48 618 48 HOH HOH A . DA 5 HOH 49 619 49 HOH HOH A . DA 5 HOH 50 620 50 HOH HOH A . DA 5 HOH 51 621 51 HOH HOH A . DA 5 HOH 52 622 52 HOH HOH A . DA 5 HOH 53 623 53 HOH HOH A . DA 5 HOH 54 624 54 HOH HOH A . DA 5 HOH 55 625 55 HOH HOH A . DA 5 HOH 56 626 56 HOH HOH A . DA 5 HOH 57 627 57 HOH HOH A . DA 5 HOH 58 628 58 HOH HOH A . DA 5 HOH 59 629 59 HOH HOH A . DA 5 HOH 60 630 60 HOH HOH A . DA 5 HOH 61 631 61 HOH HOH A . #