data_3P3Y # _entry.id 3P3Y # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.281 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3P3Y RCSB RCSB061925 WWPDB D_1000061925 # _pdbx_database_related.db_name PDB _pdbx_database_related.db_id 3P40 _pdbx_database_related.details . _pdbx_database_related.content_type unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 3P3Y _pdbx_database_status.recvd_initial_deposition_date 2010-10-05 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Liu, H.' 1 'He, X.' 2 # _citation.id primary _citation.title 'Homophilic adhesion mechanism of neurofascin, a member of the l1 family of neural cell adhesion molecules.' _citation.journal_abbrev J.Biol.Chem. _citation.journal_volume 286 _citation.page_first 797 _citation.page_last 805 _citation.year 2011 _citation.journal_id_ASTM JBCHA3 _citation.country US _citation.journal_id_ISSN 0021-9258 _citation.journal_id_CSD 0071 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 21047790 _citation.pdbx_database_id_DOI 10.1074/jbc.M110.180281 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Liu, H.' 1 primary 'Focia, P.J.' 2 primary 'He, X.' 3 # _cell.entry_id 3P3Y _cell.length_a 171.425 _cell.length_b 171.425 _cell.length_c 87.792 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 120.00 _cell.Z_PDB 12 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 3P3Y _symmetry.space_group_name_H-M 'P 65 2 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 179 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man Neurofascin 45285.199 1 ? ? 'N-terminal four Ig domains (UNP residues 25-428)' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 3 water nat water 18.015 495 ? ? ? ? # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;IEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFR SGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPIT QDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDL LLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPK NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVS VLDV ; _entity_poly.pdbx_seq_one_letter_code_can ;IEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFR SGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPIT QDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDL LLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPK NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVS VLDV ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ILE n 1 2 GLU n 1 3 ILE n 1 4 PRO n 1 5 MET n 1 6 ASP n 1 7 PRO n 1 8 SER n 1 9 ILE n 1 10 GLN n 1 11 ASN n 1 12 GLU n 1 13 LEU n 1 14 THR n 1 15 GLN n 1 16 PRO n 1 17 PRO n 1 18 THR n 1 19 ILE n 1 20 THR n 1 21 LYS n 1 22 GLN n 1 23 SER n 1 24 ALA n 1 25 LYS n 1 26 ASP n 1 27 HIS n 1 28 ILE n 1 29 VAL n 1 30 ASP n 1 31 PRO n 1 32 ARG n 1 33 ASP n 1 34 ASN n 1 35 ILE n 1 36 LEU n 1 37 ILE n 1 38 GLU n 1 39 CYS n 1 40 GLU n 1 41 ALA n 1 42 LYS n 1 43 GLY n 1 44 ASN n 1 45 PRO n 1 46 ALA n 1 47 PRO n 1 48 SER n 1 49 PHE n 1 50 HIS n 1 51 TRP n 1 52 THR n 1 53 ARG n 1 54 ASN n 1 55 SER n 1 56 ARG n 1 57 PHE n 1 58 PHE n 1 59 ASN n 1 60 ILE n 1 61 ALA n 1 62 LYS n 1 63 ASP n 1 64 PRO n 1 65 ARG n 1 66 VAL n 1 67 SER n 1 68 MET n 1 69 ARG n 1 70 ARG n 1 71 ARG n 1 72 SER n 1 73 GLY n 1 74 THR n 1 75 LEU n 1 76 VAL n 1 77 ILE n 1 78 ASP n 1 79 PHE n 1 80 ARG n 1 81 SER n 1 82 GLY n 1 83 GLY n 1 84 ARG n 1 85 PRO n 1 86 GLU n 1 87 GLU n 1 88 TYR n 1 89 GLU n 1 90 GLY n 1 91 GLU n 1 92 TYR n 1 93 GLN n 1 94 CYS n 1 95 PHE n 1 96 ALA n 1 97 ARG n 1 98 ASN n 1 99 LYS n 1 100 PHE n 1 101 GLY n 1 102 THR n 1 103 ALA n 1 104 LEU n 1 105 SER n 1 106 ASN n 1 107 ARG n 1 108 ILE n 1 109 ARG n 1 110 LEU n 1 111 GLN n 1 112 VAL n 1 113 SER n 1 114 LYS n 1 115 SER n 1 116 PRO n 1 117 LEU n 1 118 TRP n 1 119 PRO n 1 120 LYS n 1 121 GLU n 1 122 ASN n 1 123 LEU n 1 124 ASP n 1 125 PRO n 1 126 VAL n 1 127 VAL n 1 128 VAL n 1 129 GLN n 1 130 GLU n 1 131 GLY n 1 132 ALA n 1 133 PRO n 1 134 LEU n 1 135 THR n 1 136 LEU n 1 137 GLN n 1 138 CYS n 1 139 ASN n 1 140 PRO n 1 141 PRO n 1 142 PRO n 1 143 GLY n 1 144 LEU n 1 145 PRO n 1 146 SER n 1 147 PRO n 1 148 VAL n 1 149 ILE n 1 150 PHE n 1 151 TRP n 1 152 MET n 1 153 SER n 1 154 SER n 1 155 SER n 1 156 MET n 1 157 GLU n 1 158 PRO n 1 159 ILE n 1 160 THR n 1 161 GLN n 1 162 ASP n 1 163 LYS n 1 164 ARG n 1 165 VAL n 1 166 SER n 1 167 GLN n 1 168 GLY n 1 169 HIS n 1 170 ASN n 1 171 GLY n 1 172 ASP n 1 173 LEU n 1 174 TYR n 1 175 PHE n 1 176 SER n 1 177 ASN n 1 178 VAL n 1 179 MET n 1 180 LEU n 1 181 GLN n 1 182 ASP n 1 183 MET n 1 184 GLN n 1 185 THR n 1 186 ASP n 1 187 TYR n 1 188 SER n 1 189 CYS n 1 190 ASN n 1 191 ALA n 1 192 ARG n 1 193 PHE n 1 194 HIS n 1 195 PHE n 1 196 THR n 1 197 HIS n 1 198 THR n 1 199 ILE n 1 200 GLN n 1 201 GLN n 1 202 LYS n 1 203 ASN n 1 204 PRO n 1 205 PHE n 1 206 THR n 1 207 LEU n 1 208 LYS n 1 209 VAL n 1 210 LEU n 1 211 THR n 1 212 THR n 1 213 ARG n 1 214 GLY n 1 215 VAL n 1 216 ALA n 1 217 GLU n 1 218 ARG n 1 219 THR n 1 220 PRO n 1 221 SER n 1 222 PHE n 1 223 MET n 1 224 TYR n 1 225 PRO n 1 226 GLN n 1 227 GLY n 1 228 THR n 1 229 ALA n 1 230 SER n 1 231 SER n 1 232 GLN n 1 233 MET n 1 234 VAL n 1 235 LEU n 1 236 ARG n 1 237 GLY n 1 238 MET n 1 239 ASP n 1 240 LEU n 1 241 LEU n 1 242 LEU n 1 243 GLU n 1 244 CYS n 1 245 ILE n 1 246 ALA n 1 247 SER n 1 248 GLY n 1 249 VAL n 1 250 PRO n 1 251 THR n 1 252 PRO n 1 253 ASP n 1 254 ILE n 1 255 ALA n 1 256 TRP n 1 257 TYR n 1 258 LYS n 1 259 LYS n 1 260 GLY n 1 261 GLY n 1 262 ASP n 1 263 LEU n 1 264 PRO n 1 265 SER n 1 266 ASP n 1 267 LYS n 1 268 ALA n 1 269 LYS n 1 270 PHE n 1 271 GLU n 1 272 ASN n 1 273 PHE n 1 274 ASN n 1 275 LYS n 1 276 ALA n 1 277 LEU n 1 278 ARG n 1 279 ILE n 1 280 THR n 1 281 ASN n 1 282 VAL n 1 283 SER n 1 284 GLU n 1 285 GLU n 1 286 ASP n 1 287 SER n 1 288 GLY n 1 289 GLU n 1 290 TYR n 1 291 PHE n 1 292 CYS n 1 293 LEU n 1 294 ALA n 1 295 SER n 1 296 ASN n 1 297 LYS n 1 298 MET n 1 299 GLY n 1 300 SER n 1 301 ILE n 1 302 ARG n 1 303 HIS n 1 304 THR n 1 305 ILE n 1 306 SER n 1 307 VAL n 1 308 ARG n 1 309 VAL n 1 310 LYS n 1 311 ALA n 1 312 ALA n 1 313 PRO n 1 314 TYR n 1 315 TRP n 1 316 LEU n 1 317 ASP n 1 318 GLU n 1 319 PRO n 1 320 LYS n 1 321 ASN n 1 322 LEU n 1 323 ILE n 1 324 LEU n 1 325 ALA n 1 326 PRO n 1 327 GLY n 1 328 GLU n 1 329 ASP n 1 330 GLY n 1 331 ARG n 1 332 LEU n 1 333 VAL n 1 334 CYS n 1 335 ARG n 1 336 ALA n 1 337 ASN n 1 338 GLY n 1 339 ASN n 1 340 PRO n 1 341 LYS n 1 342 PRO n 1 343 THR n 1 344 VAL n 1 345 GLN n 1 346 TRP n 1 347 MET n 1 348 VAL n 1 349 ASN n 1 350 GLY n 1 351 GLU n 1 352 PRO n 1 353 LEU n 1 354 GLN n 1 355 SER n 1 356 ALA n 1 357 PRO n 1 358 PRO n 1 359 ASN n 1 360 PRO n 1 361 ASN n 1 362 ARG n 1 363 GLU n 1 364 VAL n 1 365 ALA n 1 366 GLY n 1 367 ASP n 1 368 THR n 1 369 ILE n 1 370 ILE n 1 371 PHE n 1 372 ARG n 1 373 ASP n 1 374 THR n 1 375 GLN n 1 376 ILE n 1 377 SER n 1 378 SER n 1 379 ARG n 1 380 ALA n 1 381 VAL n 1 382 TYR n 1 383 GLN n 1 384 CYS n 1 385 ASN n 1 386 THR n 1 387 SER n 1 388 ASN n 1 389 GLU n 1 390 HIS n 1 391 GLY n 1 392 TYR n 1 393 LEU n 1 394 LEU n 1 395 ALA n 1 396 ASN n 1 397 ALA n 1 398 PHE n 1 399 VAL n 1 400 SER n 1 401 VAL n 1 402 LEU n 1 403 ASP n 1 404 VAL n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'NFASC, KIAA0756' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'cabbage looper' _entity_src_gen.pdbx_host_org_scientific_name 'Trichoplusia ni' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7111 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line Hi5 _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code NFASC_HUMAN _struct_ref.pdbx_db_accession O94856 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;IEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFR SGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPIT QDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDL LLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPK NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVS VLDV ; _struct_ref.pdbx_align_begin 25 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 3P3Y _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 404 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession O94856 _struct_ref_seq.db_align_beg 25 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 428 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 25 _struct_ref_seq.pdbx_auth_seq_align_end 428 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 3P3Y _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 4.11 _exptl_crystal.density_percent_sol 70.08 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.temp 293.15 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.pdbx_details '1.4 ammonium sulfate, 0.1 M cacodylate, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 293.15K' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector 'IMAGE PLATE' _diffrn_detector.type 'MAR scanner 300 mm plate' _diffrn_detector.pdbx_collection_date 2008-08-14 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'Si(111)' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.54981 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'APS BEAMLINE 21-ID-D' _diffrn_source.pdbx_synchrotron_site APS _diffrn_source.pdbx_synchrotron_beamline 21-ID-D _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.54981 # _reflns.entry_id 3P3Y _reflns.observed_criterion_sigma_I 0.0 _reflns.observed_criterion_sigma_F 0.0 _reflns.d_resolution_low 50 _reflns.d_resolution_high 2.6 _reflns.number_obs 23568 _reflns.number_all 23854 _reflns.percent_possible_obs 98.8 _reflns.pdbx_Rmerge_I_obs 0.050 _reflns.pdbx_Rsym_value 0.054 _reflns.pdbx_netI_over_sigmaI 19.9 _reflns.B_iso_Wilson_estimate 42.6 _reflns.pdbx_redundancy 5.8 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 # _reflns_shell.d_res_high 2.6 _reflns_shell.d_res_low 2.7 _reflns_shell.percent_possible_all 96.4 _reflns_shell.Rmerge_I_obs 0.487 _reflns_shell.pdbx_Rsym_value 0.427 _reflns_shell.meanI_over_sigI_obs 2.4 _reflns_shell.pdbx_redundancy 3.9 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 2390 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_diffrn_id ? _reflns_shell.pdbx_ordinal 1 # _refine.entry_id 3P3Y _refine.ls_number_reflns_obs 23508 _refine.ls_number_reflns_all 23769 _refine.pdbx_ls_sigma_I 0.0 _refine.pdbx_ls_sigma_F 0.0 _refine.pdbx_data_cutoff_high_absF 3482001.70 _refine.pdbx_data_cutoff_low_absF 0.000000 _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 19.71 _refine.ls_d_res_high 2.60 _refine.ls_percent_reflns_obs 98.9 _refine.ls_R_factor_obs 0.258 _refine.ls_R_factor_all 0.274 _refine.ls_R_factor_R_work 0.258 _refine.ls_R_factor_R_free 0.288 _refine.ls_R_factor_R_free_error 0.009 _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 4.8 _refine.ls_number_reflns_R_free 1131 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean 89.0 _refine.aniso_B[1][1] -4.32 _refine.aniso_B[2][2] -4.32 _refine.aniso_B[3][3] 8.65 _refine.aniso_B[1][2] -2.33 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details 'FLAT MODEL' _refine.solvent_model_param_ksol 0.24541 _refine.solvent_model_param_bsol 45.1788 _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'BULK SOLVENT MODEL USED' _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct SIRAS _refine.pdbx_isotropic_thermal_model RESTRAINED _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_overall_ESU_R ? _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 3P3Y _refine_analyze.Luzzati_coordinate_error_obs 0.43 _refine_analyze.Luzzati_sigma_a_obs 0.54 _refine_analyze.Luzzati_d_res_low_obs 5.00 _refine_analyze.Luzzati_coordinate_error_free 0.50 _refine_analyze.Luzzati_sigma_a_free 0.56 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 3068 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 14 _refine_hist.number_atoms_solvent 495 _refine_hist.number_atoms_total 3577 _refine_hist.d_res_high 2.60 _refine_hist.d_res_low 19.71 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d 0.010 ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg 1.5 ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d 28.0 ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d 1.25 ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_restr_ncs.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_restr_ncs.dom_id 1 _refine_ls_restr_ncs.ncs_model_details NONE _refine_ls_restr_ncs.rms_dev_position ? _refine_ls_restr_ncs.weight_position ? _refine_ls_restr_ncs.rms_dev_B_iso ? _refine_ls_restr_ncs.weight_B_iso ? _refine_ls_restr_ncs.pdbx_ordinal 1 _refine_ls_restr_ncs.pdbx_type . _refine_ls_restr_ncs.pdbx_auth_asym_id . _refine_ls_restr_ncs.pdbx_ens_id 1 _refine_ls_restr_ncs.pdbx_number ? # _refine_ls_shell.pdbx_total_number_of_bins_used 6 _refine_ls_shell.d_res_high 2.60 _refine_ls_shell.d_res_low 2.76 _refine_ls_shell.number_reflns_R_work 3547 _refine_ls_shell.R_factor_R_work 0.366 _refine_ls_shell.percent_reflns_obs 95.6 _refine_ls_shell.R_factor_R_free 0.401 _refine_ls_shell.R_factor_R_free_error 0.032 _refine_ls_shell.percent_reflns_R_free 4.4 _refine_ls_shell.number_reflns_R_free 162 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs 3547 _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # loop_ _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file _pdbx_xplor_file.pdbx_refine_id 1 protein_rep.param protein.top 'X-RAY DIFFRACTION' 2 water_rep.param water.top 'X-RAY DIFFRACTION' 3 carbohydrate.param carbohydrate.top 'X-RAY DIFFRACTION' 4 ion.param ion.top 'X-RAY DIFFRACTION' # _struct_ncs_dom.id 1 _struct_ncs_dom.details ? _struct_ncs_dom.pdbx_ens_id 1 # _struct_ncs_ens.id 1 _struct_ncs_ens.details ? # _struct.entry_id 3P3Y _struct.title 'Crystal structure of neurofascin homophilic adhesion complex in space group p6522' _struct.pdbx_descriptor Neurofascin _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3P3Y _struct_keywords.pdbx_keywords 'CELL ADHESION' _struct_keywords.text 'Ig domains, cell adhesion' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 ASN A 59 ? ASP A 63 ? ASN A 83 ASP A 87 5 ? 5 HELX_P HELX_P2 2 LEU A 180 ? GLN A 184 ? LEU A 204 GLN A 208 5 ? 5 HELX_P HELX_P3 3 ASN A 272 ? ASN A 274 ? ASN A 296 ASN A 298 5 ? 3 HELX_P HELX_P4 4 SER A 283 ? SER A 287 ? SER A 307 SER A 311 5 ? 5 HELX_P HELX_P5 5 GLN A 354 ? ALA A 356 ? GLN A 378 ALA A 380 5 ? 3 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 39 SG ? ? ? 1_555 A CYS 94 SG ? ? A CYS 63 A CYS 118 1_555 ? ? ? ? ? ? ? 2.033 ? disulf2 disulf ? ? A CYS 138 SG ? ? ? 1_555 A CYS 189 SG ? ? A CYS 162 A CYS 213 1_555 ? ? ? ? ? ? ? 2.042 ? disulf3 disulf ? ? A CYS 244 SG ? ? ? 1_555 A CYS 292 SG ? ? A CYS 268 A CYS 316 1_555 ? ? ? ? ? ? ? 2.040 ? disulf4 disulf ? ? A CYS 334 SG ? ? ? 1_555 A CYS 384 SG ? ? A CYS 358 A CYS 408 1_555 ? ? ? ? ? ? ? 2.021 ? covale1 covale ? ? A ASN 385 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 409 A NAG 1 1_555 ? ? ? ? ? ? ? 1.294 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 LEU 144 A . ? LEU 168 A PRO 145 A ? PRO 169 A 1 -3.57 2 ASN 339 A . ? ASN 363 A PRO 340 A ? PRO 364 A 1 5.21 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 2 ? B ? 5 ? C ? 2 ? D ? 3 ? E ? 3 ? F ? 4 ? G ? 3 ? H ? 3 ? I ? 5 ? J ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel B 1 2 ? parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel B 4 5 ? anti-parallel C 1 2 ? parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel F 1 2 ? parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel G 1 2 ? parallel G 2 3 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel I 1 2 ? parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 ILE A 19 ? GLN A 22 ? ILE A 43 GLN A 46 A 2 CYS A 39 ? ALA A 41 ? CYS A 63 ALA A 65 B 1 ILE A 28 ? VAL A 29 ? ILE A 52 VAL A 53 B 2 THR A 102 ? VAL A 112 ? THR A 126 VAL A 136 B 3 GLY A 90 ? ARG A 97 ? GLY A 114 ARG A 121 B 4 SER A 48 ? ARG A 53 ? SER A 72 ARG A 77 B 5 ARG A 56 ? PHE A 57 ? ARG A 80 PHE A 81 C 1 VAL A 126 ? GLN A 129 ? VAL A 150 GLN A 153 C 2 LEU A 207 ? LEU A 210 ? LEU A 231 LEU A 234 D 1 LEU A 134 ? LEU A 136 ? LEU A 158 LEU A 160 D 2 LEU A 173 ? PHE A 175 ? LEU A 197 PHE A 199 D 3 VAL A 165 ? GLN A 167 ? VAL A 189 GLN A 191 E 1 VAL A 148 ? MET A 152 ? VAL A 172 MET A 176 E 2 SER A 188 ? ARG A 192 ? SER A 212 ARG A 216 E 3 ILE A 199 ? GLN A 201 ? ILE A 223 GLN A 225 F 1 ALA A 229 ? LEU A 235 ? ALA A 253 LEU A 259 F 2 SER A 300 ? ASP A 317 ? SER A 324 ASP A 341 F 3 GLY A 288 ? SER A 295 ? GLY A 312 SER A 319 F 4 ASP A 253 ? LYS A 258 ? ASP A 277 LYS A 282 G 1 ALA A 229 ? LEU A 235 ? ALA A 253 LEU A 259 G 2 SER A 300 ? ASP A 317 ? SER A 324 ASP A 341 G 3 ARG A 335 ? ASN A 339 ? ARG A 359 ASN A 363 H 1 LEU A 240 ? GLU A 243 ? LEU A 264 GLU A 267 H 2 ALA A 276 ? ILE A 279 ? ALA A 300 ILE A 303 H 3 ALA A 268 ? GLU A 271 ? ALA A 292 GLU A 295 I 1 LEU A 322 ? LEU A 324 ? LEU A 346 LEU A 348 I 2 GLY A 391 ? VAL A 401 ? GLY A 415 VAL A 425 I 3 VAL A 381 ? ASN A 388 ? VAL A 405 ASN A 412 I 4 THR A 343 ? VAL A 348 ? THR A 367 VAL A 372 I 5 GLU A 351 ? PRO A 352 ? GLU A 375 PRO A 376 J 1 GLY A 330 ? VAL A 333 ? GLY A 354 VAL A 357 J 2 THR A 368 ? PHE A 371 ? THR A 392 PHE A 395 J 3 ARG A 362 ? ALA A 365 ? ARG A 386 ALA A 389 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N THR A 20 ? N THR A 44 O GLU A 40 ? O GLU A 64 B 1 2 N VAL A 29 ? N VAL A 53 O GLN A 111 ? O GLN A 135 B 2 3 O ALA A 103 ? O ALA A 127 N ALA A 96 ? N ALA A 120 B 3 4 O ARG A 97 ? O ARG A 121 N SER A 48 ? N SER A 72 B 4 5 N ARG A 53 ? N ARG A 77 O ARG A 56 ? O ARG A 80 C 1 2 N VAL A 126 ? N VAL A 150 O LYS A 208 ? O LYS A 232 D 1 2 N LEU A 136 ? N LEU A 160 O LEU A 173 ? O LEU A 197 D 2 3 O TYR A 174 ? O TYR A 198 N SER A 166 ? N SER A 190 E 1 2 N VAL A 148 ? N VAL A 172 O ARG A 192 ? O ARG A 216 E 2 3 N ALA A 191 ? N ALA A 215 O GLN A 200 ? O GLN A 224 F 1 2 N SER A 230 ? N SER A 254 O SER A 306 ? O SER A 330 F 2 3 O ILE A 305 ? O ILE A 329 N TYR A 290 ? N TYR A 314 F 3 4 O PHE A 291 ? O PHE A 315 N TYR A 257 ? N TYR A 281 G 1 2 N SER A 230 ? N SER A 254 O SER A 306 ? O SER A 330 G 2 3 N ASP A 317 ? N ASP A 341 O ARG A 335 ? O ARG A 359 H 1 2 N LEU A 242 ? N LEU A 266 O LEU A 277 ? O LEU A 301 H 2 3 O ARG A 278 ? O ARG A 302 N LYS A 269 ? N LYS A 293 I 1 2 N LEU A 322 ? N LEU A 346 O PHE A 398 ? O PHE A 422 I 2 3 O GLY A 391 ? O GLY A 415 N ASN A 388 ? N ASN A 412 I 3 4 O GLN A 383 ? O GLN A 407 N MET A 347 ? N MET A 371 I 4 5 N VAL A 348 ? N VAL A 372 O GLU A 351 ? O GLU A 375 J 1 2 N LEU A 332 ? N LEU A 356 O ILE A 369 ? O ILE A 393 J 2 3 O THR A 368 ? O THR A 392 N ALA A 365 ? N ALA A 389 # _struct_site.id AC1 _struct_site.pdbx_evidence_code Software _struct_site.pdbx_auth_asym_id ? _struct_site.pdbx_auth_comp_id ? _struct_site.pdbx_auth_seq_id ? _struct_site.pdbx_auth_ins_code ? _struct_site.pdbx_num_residues 8 _struct_site.details 'BINDING SITE FOR RESIDUE NAG A 1' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 8 ARG A 107 ? ARG A 131 . ? 1_555 ? 2 AC1 8 GLN A 226 ? GLN A 250 . ? 10_666 ? 3 AC1 8 GLN A 345 ? GLN A 369 . ? 1_555 ? 4 AC1 8 ASN A 385 ? ASN A 409 . ? 1_555 ? 5 AC1 8 SER A 387 ? SER A 411 . ? 1_555 ? 6 AC1 8 TYR A 392 ? TYR A 416 . ? 1_555 ? 7 AC1 8 HOH C . ? HOH A 737 . ? 1_555 ? 8 AC1 8 HOH C . ? HOH A 872 . ? 1_555 ? # _database_PDB_matrix.entry_id 3P3Y _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 3P3Y _atom_sites.fract_transf_matrix[1][1] 0.005833 _atom_sites.fract_transf_matrix[1][2] 0.003368 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.006736 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.011391 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . LEU A 1 13 ? 20.872 67.182 5.944 1.00 164.73 ? 37 LEU A N 1 ATOM 2 C CA . LEU A 1 13 ? 19.404 66.981 5.989 1.00 164.73 ? 37 LEU A CA 1 ATOM 3 C C . LEU A 1 13 ? 18.912 66.527 7.371 1.00 164.65 ? 37 LEU A C 1 ATOM 4 O O . LEU A 1 13 ? 18.615 67.368 8.226 1.00 164.69 ? 37 LEU A O 1 ATOM 5 C CB . LEU A 1 13 ? 18.959 65.965 4.910 1.00 121.08 ? 37 LEU A CB 1 ATOM 6 C CG . LEU A 1 13 ? 17.483 66.006 4.461 1.00 121.49 ? 37 LEU A CG 1 ATOM 7 C CD1 . LEU A 1 13 ? 17.302 66.967 3.278 1.00 121.61 ? 37 LEU A CD1 1 ATOM 8 C CD2 . LEU A 1 13 ? 17.011 64.610 4.081 1.00 121.78 ? 37 LEU A CD2 1 ATOM 9 N N . THR A 1 14 ? 18.879 65.209 7.599 1.00 193.19 ? 38 THR A N 1 ATOM 10 C CA . THR A 1 14 ? 18.318 64.637 8.827 1.00 192.91 ? 38 THR A CA 1 ATOM 11 C C . THR A 1 14 ? 19.069 64.847 10.144 1.00 192.71 ? 38 THR A C 1 ATOM 12 O O . THR A 1 14 ? 19.720 63.936 10.667 1.00 192.74 ? 38 THR A O 1 ATOM 13 C CB . THR A 1 14 ? 17.983 63.104 8.622 1.00 116.75 ? 38 THR A CB 1 ATOM 14 O OG1 . THR A 1 14 ? 17.543 62.526 9.862 1.00 116.63 ? 38 THR A OG1 1 ATOM 15 C CG2 . THR A 1 14 ? 19.197 62.339 8.087 1.00 116.63 ? 38 THR A CG2 1 ATOM 16 N N . GLN A 1 15 ? 18.968 66.063 10.680 1.00 159.04 ? 39 GLN A N 1 ATOM 17 C CA . GLN A 1 15 ? 19.589 66.374 11.962 1.00 158.60 ? 39 GLN A CA 1 ATOM 18 C C . GLN A 1 15 ? 18.617 67.026 12.963 1.00 158.06 ? 39 GLN A C 1 ATOM 19 O O . GLN A 1 15 ? 17.853 67.934 12.602 1.00 158.01 ? 39 GLN A O 1 ATOM 20 C CB . GLN A 1 15 ? 20.849 67.262 11.782 1.00 138.55 ? 39 GLN A CB 1 ATOM 21 C CG . GLN A 1 15 ? 20.648 68.583 11.028 1.00 139.00 ? 39 GLN A CG 1 ATOM 22 C CD . GLN A 1 15 ? 21.954 69.346 10.791 1.00 139.64 ? 39 GLN A CD 1 ATOM 23 O OE1 . GLN A 1 15 ? 22.779 69.500 11.699 1.00 139.72 ? 39 GLN A OE1 1 ATOM 24 N NE2 . GLN A 1 15 ? 22.137 69.836 9.568 1.00 139.60 ? 39 GLN A NE2 1 ATOM 25 N N . PRO A 1 16 ? 18.605 66.520 14.226 1.00 151.68 ? 40 PRO A N 1 ATOM 26 C CA . PRO A 1 16 ? 17.767 67.003 15.337 1.00 145.05 ? 40 PRO A CA 1 ATOM 27 C C . PRO A 1 16 ? 18.035 68.493 15.632 1.00 135.55 ? 40 PRO A C 1 ATOM 28 O O . PRO A 1 16 ? 18.988 69.075 15.097 1.00 147.70 ? 40 PRO A O 1 ATOM 29 C CB . PRO A 1 16 ? 18.174 66.106 16.500 1.00 117.28 ? 40 PRO A CB 1 ATOM 30 C CG . PRO A 1 16 ? 18.523 64.820 15.848 1.00 115.65 ? 40 PRO A CG 1 ATOM 31 C CD . PRO A 1 16 ? 19.246 65.234 14.581 1.00 122.17 ? 40 PRO A CD 1 ATOM 32 N N . PRO A 1 17 ? 17.221 69.112 16.515 1.00 92.44 ? 41 PRO A N 1 ATOM 33 C CA . PRO A 1 17 ? 17.387 70.536 16.845 1.00 83.99 ? 41 PRO A CA 1 ATOM 34 C C . PRO A 1 17 ? 18.694 70.914 17.520 1.00 83.89 ? 41 PRO A C 1 ATOM 35 O O . PRO A 1 17 ? 19.234 70.149 18.324 1.00 82.58 ? 41 PRO A O 1 ATOM 36 C CB . PRO A 1 17 ? 16.187 70.846 17.752 1.00 58.31 ? 41 PRO A CB 1 ATOM 37 C CG . PRO A 1 17 ? 15.254 69.687 17.584 1.00 53.40 ? 41 PRO A CG 1 ATOM 38 C CD . PRO A 1 17 ? 16.135 68.511 17.316 1.00 65.11 ? 41 PRO A CD 1 ATOM 39 N N . THR A 1 18 ? 19.192 72.101 17.189 1.00 82.05 ? 42 THR A N 1 ATOM 40 C CA . THR A 1 18 ? 20.418 72.609 17.778 1.00 85.78 ? 42 THR A CA 1 ATOM 41 C C . THR A 1 18 ? 20.283 74.124 17.911 1.00 83.88 ? 42 THR A C 1 ATOM 42 O O . THR A 1 18 ? 20.050 74.815 16.916 1.00 82.47 ? 42 THR A O 1 ATOM 43 C CB . THR A 1 18 ? 21.649 72.241 16.909 1.00 93.61 ? 42 THR A CB 1 ATOM 44 O OG1 . THR A 1 18 ? 21.793 70.813 16.872 1.00 97.63 ? 42 THR A OG1 1 ATOM 45 C CG2 . THR A 1 18 ? 22.924 72.849 17.481 1.00 98.12 ? 42 THR A CG2 1 ATOM 46 N N . ILE A 1 19 ? 20.412 74.629 19.142 1.00 80.91 ? 43 ILE A N 1 ATOM 47 C CA . ILE A 1 19 ? 20.290 76.067 19.411 1.00 80.09 ? 43 ILE A CA 1 ATOM 48 C C . ILE A 1 19 ? 21.355 76.855 18.640 1.00 82.86 ? 43 ILE A C 1 ATOM 49 O O . ILE A 1 19 ? 22.550 76.563 18.707 1.00 80.16 ? 43 ILE A O 1 ATOM 50 C CB . ILE A 1 19 ? 20.333 76.368 20.951 1.00 87.23 ? 43 ILE A CB 1 ATOM 51 C CG1 . ILE A 1 19 ? 18.945 76.152 21.562 1.00 86.07 ? 43 ILE A CG1 1 ATOM 52 C CG2 . ILE A 1 19 ? 20.760 77.809 21.215 1.00 88.19 ? 43 ILE A CG2 1 ATOM 53 C CD1 . ILE A 1 19 ? 18.969 75.838 23.018 1.00 85.06 ? 43 ILE A CD1 1 ATOM 54 N N . THR A 1 20 ? 20.884 77.851 17.896 1.00 89.37 ? 44 THR A N 1 ATOM 55 C CA . THR A 1 20 ? 21.711 78.670 17.018 1.00 95.65 ? 44 THR A CA 1 ATOM 56 C C . THR A 1 20 ? 22.135 79.952 17.704 1.00 88.03 ? 44 THR A C 1 ATOM 57 O O . THR A 1 20 ? 23.295 80.364 17.614 1.00 81.75 ? 44 THR A O 1 ATOM 58 C CB . THR A 1 20 ? 20.911 79.001 15.712 1.00 127.40 ? 44 THR A CB 1 ATOM 59 O OG1 . THR A 1 20 ? 20.754 77.806 14.932 1.00 145.53 ? 44 THR A OG1 1 ATOM 60 C CG2 . THR A 1 20 ? 21.610 80.073 14.876 1.00 146.02 ? 44 THR A CG2 1 ATOM 61 N N . LYS A 1 21 ? 21.181 80.563 18.394 1.00 85.90 ? 45 LYS A N 1 ATOM 62 C CA . LYS A 1 21 ? 21.396 81.806 19.108 1.00 82.86 ? 45 LYS A CA 1 ATOM 63 C C . LYS A 1 21 ? 20.466 81.803 20.317 1.00 80.07 ? 45 LYS A C 1 ATOM 64 O O . LYS A 1 21 ? 19.475 81.069 20.339 1.00 81.81 ? 45 LYS A O 1 ATOM 65 C CB . LYS A 1 21 ? 21.044 82.993 18.194 1.00 81.87 ? 45 LYS A CB 1 ATOM 66 C CG . LYS A 1 21 ? 21.497 84.352 18.709 1.00 84.59 ? 45 LYS A CG 1 ATOM 67 C CD . LYS A 1 21 ? 20.762 85.510 18.031 1.00 85.45 ? 45 LYS A CD 1 ATOM 68 C CE . LYS A 1 21 ? 21.414 85.933 16.724 1.00 86.21 ? 45 LYS A CE 1 ATOM 69 N NZ . LYS A 1 21 ? 20.815 87.194 16.199 1.00 86.23 ? 45 LYS A NZ 1 ATOM 70 N N . GLN A 1 22 ? 20.809 82.599 21.328 1.00 75.40 ? 46 GLN A N 1 ATOM 71 C CA . GLN A 1 22 ? 19.978 82.765 22.520 1.00 71.60 ? 46 GLN A CA 1 ATOM 72 C C . GLN A 1 22 ? 20.416 83.976 23.327 1.00 71.59 ? 46 GLN A C 1 ATOM 73 O O . GLN A 1 22 ? 21.584 84.375 23.275 1.00 71.67 ? 46 GLN A O 1 ATOM 74 C CB . GLN A 1 22 ? 20.020 81.523 23.418 1.00 64.91 ? 46 GLN A CB 1 ATOM 75 C CG . GLN A 1 22 ? 21.403 81.071 23.848 1.00 60.46 ? 46 GLN A CG 1 ATOM 76 C CD . GLN A 1 22 ? 21.362 79.815 24.703 1.00 59.15 ? 46 GLN A CD 1 ATOM 77 O OE1 . GLN A 1 22 ? 21.862 78.761 24.307 1.00 58.54 ? 46 GLN A OE1 1 ATOM 78 N NE2 . GLN A 1 22 ? 20.757 79.918 25.883 1.00 58.48 ? 46 GLN A NE2 1 ATOM 79 N N . SER A 1 23 ? 19.467 84.575 24.048 1.00 71.18 ? 47 SER A N 1 ATOM 80 C CA . SER A 1 23 ? 19.760 85.707 24.930 1.00 74.35 ? 47 SER A CA 1 ATOM 81 C C . SER A 1 23 ? 20.775 85.277 25.989 1.00 76.57 ? 47 SER A C 1 ATOM 82 O O . SER A 1 23 ? 20.877 84.096 26.326 1.00 76.24 ? 47 SER A O 1 ATOM 83 C CB . SER A 1 23 ? 18.486 86.202 25.619 1.00 69.13 ? 47 SER A CB 1 ATOM 84 O OG . SER A 1 23 ? 17.823 87.158 24.814 1.00 70.56 ? 47 SER A OG 1 ATOM 85 N N . ALA A 1 24 ? 21.527 86.240 26.506 1.00 79.92 ? 48 ALA A N 1 ATOM 86 C CA . ALA A 1 24 ? 22.544 85.951 27.507 1.00 80.16 ? 48 ALA A CA 1 ATOM 87 C C . ALA A 1 24 ? 21.943 85.353 28.776 1.00 78.47 ? 48 ALA A C 1 ATOM 88 O O . ALA A 1 24 ? 20.804 85.647 29.132 1.00 83.10 ? 48 ALA A O 1 ATOM 89 C CB . ALA A 1 24 ? 23.314 87.231 27.850 1.00 67.26 ? 48 ALA A CB 1 ATOM 90 N N . LYS A 1 25 ? 22.718 84.491 29.433 1.00 75.71 ? 49 LYS A N 1 ATOM 91 C CA . LYS A 1 25 ? 22.337 83.866 30.703 1.00 72.10 ? 49 LYS A CA 1 ATOM 92 C C . LYS A 1 25 ? 21.807 84.935 31.670 1.00 71.55 ? 49 LYS A C 1 ATOM 93 O O . LYS A 1 25 ? 20.807 84.723 32.356 1.00 67.63 ? 49 LYS A O 1 ATOM 94 C CB . LYS A 1 25 ? 23.558 83.179 31.326 1.00 72.55 ? 49 LYS A CB 1 ATOM 95 C CG . LYS A 1 25 ? 23.236 81.981 32.191 1.00 70.73 ? 49 LYS A CG 1 ATOM 96 C CD . LYS A 1 25 ? 23.667 80.683 31.528 1.00 70.85 ? 49 LYS A CD 1 ATOM 97 C CE . LYS A 1 25 ? 25.075 80.286 31.934 1.00 71.41 ? 49 LYS A CE 1 ATOM 98 N NZ . LYS A 1 25 ? 25.372 78.871 31.559 1.00 72.66 ? 49 LYS A NZ 1 ATOM 99 N N . ASP A 1 26 ? 22.496 86.073 31.723 1.00 73.83 ? 50 ASP A N 1 ATOM 100 C CA . ASP A 1 26 ? 22.084 87.198 32.567 1.00 82.98 ? 50 ASP A CA 1 ATOM 101 C C . ASP A 1 26 ? 21.635 88.329 31.630 1.00 88.78 ? 50 ASP A C 1 ATOM 102 O O . ASP A 1 26 ? 22.398 89.251 31.332 1.00 86.28 ? 50 ASP A O 1 ATOM 103 C CB . ASP A 1 26 ? 23.252 87.651 33.445 1.00 92.53 ? 50 ASP A CB 1 ATOM 104 C CG . ASP A 1 26 ? 22.817 88.595 34.547 1.00 93.98 ? 50 ASP A CG 1 ATOM 105 O OD1 . ASP A 1 26 ? 21.807 88.303 35.229 1.00 94.67 ? 50 ASP A OD1 1 ATOM 106 O OD2 . ASP A 1 26 ? 23.496 89.625 34.742 1.00 93.41 ? 50 ASP A OD2 1 ATOM 107 N N . HIS A 1 27 ? 20.383 88.247 31.176 1.00 95.03 ? 51 HIS A N 1 ATOM 108 C CA . HIS A 1 27 ? 19.852 89.208 30.208 1.00 98.27 ? 51 HIS A CA 1 ATOM 109 C C . HIS A 1 27 ? 19.214 90.418 30.867 1.00 101.17 ? 51 HIS A C 1 ATOM 110 O O . HIS A 1 27 ? 18.063 90.385 31.314 1.00 102.33 ? 51 HIS A O 1 ATOM 111 C CB . HIS A 1 27 ? 18.870 88.510 29.260 1.00 99.05 ? 51 HIS A CB 1 ATOM 112 C CG . HIS A 1 27 ? 18.879 89.073 27.873 1.00 98.74 ? 51 HIS A CG 1 ATOM 113 N ND1 . HIS A 1 27 ? 17.752 89.595 27.276 1.00 98.56 ? 51 HIS A ND1 1 ATOM 114 C CD2 . HIS A 1 27 ? 19.881 89.204 26.969 1.00 98.98 ? 51 HIS A CD2 1 ATOM 115 C CE1 . HIS A 1 27 ? 18.058 90.022 26.064 1.00 99.38 ? 51 HIS A CE1 1 ATOM 116 N NE2 . HIS A 1 27 ? 19.343 89.796 25.852 1.00 99.98 ? 51 HIS A NE2 1 ATOM 117 N N . ILE A 1 28 ? 19.995 91.495 30.913 1.00 95.39 ? 52 ILE A N 1 ATOM 118 C CA . ILE A 1 28 ? 19.587 92.742 31.556 1.00 95.25 ? 52 ILE A CA 1 ATOM 119 C C . ILE A 1 28 ? 19.110 93.772 30.540 1.00 89.80 ? 52 ILE A C 1 ATOM 120 O O . ILE A 1 28 ? 19.736 93.960 29.493 1.00 88.08 ? 52 ILE A O 1 ATOM 121 C CB . ILE A 1 28 ? 20.756 93.320 32.408 1.00 103.32 ? 52 ILE A CB 1 ATOM 122 C CG1 . ILE A 1 28 ? 22.080 93.227 31.636 1.00 109.26 ? 52 ILE A CG1 1 ATOM 123 C CG2 . ILE A 1 28 ? 20.859 92.573 33.734 1.00 113.04 ? 52 ILE A CG2 1 ATOM 124 C CD1 . ILE A 1 28 ? 22.309 94.345 30.640 1.00 102.44 ? 52 ILE A CD1 1 ATOM 125 N N . VAL A 1 29 ? 17.995 94.428 30.852 1.00 100.87 ? 53 VAL A N 1 ATOM 126 C CA . VAL A 1 29 ? 17.410 95.413 29.945 1.00 106.28 ? 53 VAL A CA 1 ATOM 127 C C . VAL A 1 29 ? 16.815 96.661 30.615 1.00 114.15 ? 53 VAL A C 1 ATOM 128 O O . VAL A 1 29 ? 16.315 96.601 31.748 1.00 115.17 ? 53 VAL A O 1 ATOM 129 C CB . VAL A 1 29 ? 16.266 94.774 29.057 1.00 96.92 ? 53 VAL A CB 1 ATOM 130 C CG1 . VAL A 1 29 ? 16.867 93.928 27.932 1.00 90.57 ? 53 VAL A CG1 1 ATOM 131 C CG2 . VAL A 1 29 ? 15.308 93.952 29.925 1.00 90.07 ? 53 VAL A CG2 1 ATOM 132 N N . ASP A 1 30 ? 16.906 97.788 29.903 1.00 154.68 ? 54 ASP A N 1 ATOM 133 C CA . ASP A 1 30 ? 16.297 99.051 30.331 1.00 170.06 ? 54 ASP A CA 1 ATOM 134 C C . ASP A 1 30 ? 14.834 99.065 29.868 1.00 177.20 ? 54 ASP A C 1 ATOM 135 O O . ASP A 1 30 ? 14.517 98.542 28.794 1.00 194.36 ? 54 ASP A O 1 ATOM 136 C CB . ASP A 1 30 ? 17.028 100.267 29.732 1.00 131.20 ? 54 ASP A CB 1 ATOM 137 C CG . ASP A 1 30 ? 17.315 100.131 28.230 1.00 112.06 ? 54 ASP A CG 1 ATOM 138 O OD1 . ASP A 1 30 ? 17.875 101.093 27.652 1.00 99.79 ? 54 ASP A OD1 1 ATOM 139 O OD2 . ASP A 1 30 ? 17.000 99.079 27.627 1.00 100.48 ? 54 ASP A OD2 1 ATOM 140 N N . PRO A 1 31 ? 13.923 99.647 30.681 1.00 171.49 ? 55 PRO A N 1 ATOM 141 C CA . PRO A 1 31 ? 12.493 99.711 30.323 1.00 176.14 ? 55 PRO A CA 1 ATOM 142 C C . PRO A 1 31 ? 12.216 100.438 28.995 1.00 185.65 ? 55 PRO A C 1 ATOM 143 O O . PRO A 1 31 ? 11.052 100.605 28.612 1.00 194.36 ? 55 PRO A O 1 ATOM 144 C CB . PRO A 1 31 ? 11.863 100.461 31.502 1.00 100.13 ? 55 PRO A CB 1 ATOM 145 C CG . PRO A 1 31 ? 12.768 100.152 32.652 1.00 81.40 ? 55 PRO A CG 1 ATOM 146 C CD . PRO A 1 31 ? 14.157 100.140 32.055 1.00 99.63 ? 55 PRO A CD 1 ATOM 147 N N . ARG A 1 32 ? 13.286 100.849 28.306 1.00 143.46 ? 56 ARG A N 1 ATOM 148 C CA . ARG A 1 32 ? 13.205 101.591 27.042 1.00 126.42 ? 56 ARG A CA 1 ATOM 149 C C . ARG A 1 32 ? 12.638 100.744 25.895 1.00 124.23 ? 56 ARG A C 1 ATOM 150 O O . ARG A 1 32 ? 11.437 100.444 25.892 1.00 120.52 ? 56 ARG A O 1 ATOM 151 C CB . ARG A 1 32 ? 14.593 102.144 26.685 1.00 123.27 ? 56 ARG A CB 1 ATOM 152 C CG . ARG A 1 32 ? 14.569 103.347 25.758 1.00 113.35 ? 56 ARG A CG 1 ATOM 153 C CD . ARG A 1 32 ? 15.975 103.779 25.388 1.00 109.75 ? 56 ARG A CD 1 ATOM 154 N NE . ARG A 1 32 ? 16.647 104.476 26.482 1.00 108.93 ? 56 ARG A NE 1 ATOM 155 C CZ . ARG A 1 32 ? 17.909 104.903 26.445 1.00 109.11 ? 56 ARG A CZ 1 ATOM 156 N NH1 . ARG A 1 32 ? 18.660 104.707 25.364 1.00 109.46 ? 56 ARG A NH1 1 ATOM 157 N NH2 . ARG A 1 32 ? 18.422 105.535 27.493 1.00 109.25 ? 56 ARG A NH2 1 ATOM 158 N N . ASP A 1 33 ? 13.475 100.366 24.922 1.00 135.15 ? 57 ASP A N 1 ATOM 159 C CA . ASP A 1 33 ? 12.989 99.537 23.809 1.00 145.01 ? 57 ASP A CA 1 ATOM 160 C C . ASP A 1 33 ? 12.635 98.153 24.349 1.00 144.18 ? 57 ASP A C 1 ATOM 161 O O . ASP A 1 33 ? 13.435 97.505 25.029 1.00 147.03 ? 57 ASP A O 1 ATOM 162 C CB . ASP A 1 33 ? 14.008 99.437 22.670 1.00 168.61 ? 57 ASP A CB 1 ATOM 163 C CG . ASP A 1 33 ? 13.427 98.754 21.421 1.00 171.22 ? 57 ASP A CG 1 ATOM 164 O OD1 . ASP A 1 33 ? 14.211 98.417 20.507 1.00 171.74 ? 57 ASP A OD1 1 ATOM 165 O OD2 . ASP A 1 33 ? 12.191 98.552 21.349 1.00 171.63 ? 57 ASP A OD2 1 ATOM 166 N N . ASN A 1 34 ? 11.415 97.724 24.026 1.00 165.76 ? 58 ASN A N 1 ATOM 167 C CA . ASN A 1 34 ? 10.834 96.486 24.535 1.00 159.82 ? 58 ASN A CA 1 ATOM 168 C C . ASN A 1 34 ? 11.721 95.251 24.412 1.00 153.96 ? 58 ASN A C 1 ATOM 169 O O . ASN A 1 34 ? 12.486 95.105 23.451 1.00 158.87 ? 58 ASN A O 1 ATOM 170 C CB . ASN A 1 34 ? 9.453 96.264 23.908 1.00 139.94 ? 58 ASN A CB 1 ATOM 171 C CG . ASN A 1 34 ? 8.491 97.431 24.159 1.00 135.85 ? 58 ASN A CG 1 ATOM 172 O OD1 . ASN A 1 34 ? 8.110 97.713 25.297 1.00 133.15 ? 58 ASN A OD1 1 ATOM 173 N ND2 . ASN A 1 34 ? 8.094 98.107 23.085 1.00 132.87 ? 58 ASN A ND2 1 ATOM 174 N N . ILE A 1 35 ? 11.586 94.367 25.402 1.00 110.25 ? 59 ILE A N 1 ATOM 175 C CA . ILE A 1 35 ? 12.407 93.165 25.560 1.00 98.69 ? 59 ILE A CA 1 ATOM 176 C C . ILE A 1 35 ? 12.456 92.231 24.358 1.00 99.47 ? 59 ILE A C 1 ATOM 177 O O . ILE A 1 35 ? 11.504 92.148 23.592 1.00 91.88 ? 59 ILE A O 1 ATOM 178 C CB . ILE A 1 35 ? 11.932 92.381 26.829 1.00 85.42 ? 59 ILE A CB 1 ATOM 179 C CG1 . ILE A 1 35 ? 11.982 93.290 28.071 1.00 78.14 ? 59 ILE A CG1 1 ATOM 180 C CG2 . ILE A 1 35 ? 12.781 91.138 27.048 1.00 79.26 ? 59 ILE A CG2 1 ATOM 181 C CD1 . ILE A 1 35 ? 11.089 94.502 28.090 1.00 74.01 ? 59 ILE A CD1 1 ATOM 182 N N . LEU A 1 36 ? 13.585 91.548 24.185 1.00 102.73 ? 60 LEU A N 1 ATOM 183 C CA . LEU A 1 36 ? 13.733 90.575 23.107 1.00 104.57 ? 60 LEU A CA 1 ATOM 184 C C . LEU A 1 36 ? 14.454 89.293 23.580 1.00 105.89 ? 60 LEU A C 1 ATOM 185 O O . LEU A 1 36 ? 15.653 89.115 23.347 1.00 112.51 ? 60 LEU A O 1 ATOM 186 C CB . LEU A 1 36 ? 14.474 91.185 21.911 1.00 109.52 ? 60 LEU A CB 1 ATOM 187 C CG . LEU A 1 36 ? 14.233 90.523 20.542 1.00 106.76 ? 60 LEU A CG 1 ATOM 188 C CD1 . LEU A 1 36 ? 12.959 91.085 19.910 1.00 105.41 ? 60 LEU A CD1 1 ATOM 189 C CD2 . LEU A 1 36 ? 15.427 90.762 19.619 1.00 105.42 ? 60 LEU A CD2 1 ATOM 190 N N . ILE A 1 37 ? 13.710 88.414 24.259 1.00 87.91 ? 61 ILE A N 1 ATOM 191 C CA . ILE A 1 37 ? 14.237 87.126 24.732 1.00 72.83 ? 61 ILE A CA 1 ATOM 192 C C . ILE A 1 37 ? 14.461 86.252 23.498 1.00 72.81 ? 61 ILE A C 1 ATOM 193 O O . ILE A 1 37 ? 13.527 85.667 22.959 1.00 74.54 ? 61 ILE A O 1 ATOM 194 C CB . ILE A 1 37 ? 13.235 86.393 25.657 1.00 65.09 ? 61 ILE A CB 1 ATOM 195 C CG1 . ILE A 1 37 ? 12.489 87.382 26.571 1.00 56.27 ? 61 ILE A CG1 1 ATOM 196 C CG2 . ILE A 1 37 ? 13.981 85.321 26.446 1.00 56.81 ? 61 ILE A CG2 1 ATOM 197 C CD1 . ILE A 1 37 ? 13.320 88.049 27.677 1.00 60.69 ? 61 ILE A CD1 1 ATOM 198 N N . GLU A 1 38 ? 15.708 86.151 23.070 1.00 74.14 ? 62 GLU A N 1 ATOM 199 C CA . GLU A 1 38 ? 16.034 85.429 21.852 1.00 74.54 ? 62 GLU A CA 1 ATOM 200 C C . GLU A 1 38 ? 16.213 83.938 22.032 1.00 70.18 ? 62 GLU A C 1 ATOM 201 O O . GLU A 1 38 ? 16.628 83.487 23.087 1.00 64.24 ? 62 GLU A O 1 ATOM 202 C CB . GLU A 1 38 ? 17.308 86.043 21.223 1.00 100.49 ? 62 GLU A CB 1 ATOM 203 C CG . GLU A 1 38 ? 17.093 87.450 20.641 1.00 117.78 ? 62 GLU A CG 1 ATOM 204 C CD . GLU A 1 38 ? 18.384 88.228 20.401 1.00 125.17 ? 62 GLU A CD 1 ATOM 205 O OE1 . GLU A 1 38 ? 19.381 87.632 19.927 1.00 126.95 ? 62 GLU A OE1 1 ATOM 206 O OE2 . GLU A 1 38 ? 18.391 89.449 20.676 1.00 127.12 ? 62 GLU A OE2 1 ATOM 207 N N . CYS A 1 39 ? 15.839 83.184 21.001 1.00 74.66 ? 63 CYS A N 1 ATOM 208 C CA . CYS A 1 39 ? 16.044 81.737 20.931 1.00 74.99 ? 63 CYS A CA 1 ATOM 209 C C . CYS A 1 39 ? 15.783 81.251 19.510 1.00 77.03 ? 63 CYS A C 1 ATOM 210 O O . CYS A 1 39 ? 14.666 81.362 19.004 1.00 79.76 ? 63 CYS A O 1 ATOM 211 C CB . CYS A 1 39 ? 15.151 80.960 21.894 1.00 67.14 ? 63 CYS A CB 1 ATOM 212 S SG . CYS A 1 39 ? 15.410 79.157 21.799 1.00 67.47 ? 63 CYS A SG 1 ATOM 213 N N . GLU A 1 40 ? 16.825 80.723 18.870 1.00 75.83 ? 64 GLU A N 1 ATOM 214 C CA . GLU A 1 40 ? 16.731 80.213 17.507 1.00 76.50 ? 64 GLU A CA 1 ATOM 215 C C . GLU A 1 40 ? 17.374 78.840 17.439 1.00 75.32 ? 64 GLU A C 1 ATOM 216 O O . GLU A 1 40 ? 18.199 78.501 18.285 1.00 74.93 ? 64 GLU A O 1 ATOM 217 C CB . GLU A 1 40 ? 17.416 81.177 16.525 1.00 89.15 ? 64 GLU A CB 1 ATOM 218 C CG . GLU A 1 40 ? 16.678 82.506 16.355 1.00 93.96 ? 64 GLU A CG 1 ATOM 219 C CD . GLU A 1 40 ? 17.488 83.560 15.610 1.00 95.87 ? 64 GLU A CD 1 ATOM 220 O OE1 . GLU A 1 40 ? 18.477 83.194 14.936 1.00 96.23 ? 64 GLU A OE1 1 ATOM 221 O OE2 . GLU A 1 40 ? 17.124 84.757 15.697 1.00 94.97 ? 64 GLU A OE2 1 ATOM 222 N N . ALA A 1 41 ? 16.999 78.054 16.434 1.00 79.56 ? 65 ALA A N 1 ATOM 223 C CA . ALA A 1 41 ? 17.529 76.705 16.283 1.00 79.35 ? 65 ALA A CA 1 ATOM 224 C C . ALA A 1 41 ? 17.477 76.171 14.859 1.00 79.98 ? 65 ALA A C 1 ATOM 225 O O . ALA A 1 41 ? 16.671 76.620 14.043 1.00 85.62 ? 65 ALA A O 1 ATOM 226 C CB . ALA A 1 41 ? 16.752 75.736 17.205 1.00 65.55 ? 65 ALA A CB 1 ATOM 227 N N . LYS A 1 42 ? 18.367 75.224 14.574 1.00 93.90 ? 66 LYS A N 1 ATOM 228 C CA . LYS A 1 42 ? 18.384 74.511 13.297 1.00 99.71 ? 66 LYS A CA 1 ATOM 229 C C . LYS A 1 42 ? 17.472 73.272 13.452 1.00 99.64 ? 66 LYS A C 1 ATOM 230 O O . LYS A 1 42 ? 16.681 73.196 14.394 1.00 97.72 ? 66 LYS A O 1 ATOM 231 C CB . LYS A 1 42 ? 19.801 74.053 12.939 1.00 98.04 ? 66 LYS A CB 1 ATOM 232 C CG . LYS A 1 42 ? 20.806 75.180 12.713 1.00 105.10 ? 66 LYS A CG 1 ATOM 233 C CD . LYS A 1 42 ? 22.220 74.607 12.643 1.00 108.23 ? 66 LYS A CD 1 ATOM 234 C CE . LYS A 1 42 ? 23.235 75.609 12.113 1.00 108.24 ? 66 LYS A CE 1 ATOM 235 N NZ . LYS A 1 42 ? 24.572 74.972 11.934 1.00 107.93 ? 66 LYS A NZ 1 ATOM 236 N N . GLY A 1 43 ? 17.597 72.314 12.529 1.00 107.48 ? 67 GLY A N 1 ATOM 237 C CA . GLY A 1 43 ? 16.785 71.099 12.547 1.00 118.42 ? 67 GLY A CA 1 ATOM 238 C C . GLY A 1 43 ? 16.260 70.744 11.158 1.00 126.37 ? 67 GLY A C 1 ATOM 239 O O . GLY A 1 43 ? 15.961 71.651 10.369 1.00 123.95 ? 67 GLY A O 1 ATOM 240 N N . ASN A 1 44 ? 16.152 69.437 10.851 1.00 130.52 ? 68 ASN A N 1 ATOM 241 C CA . ASN A 1 44 ? 15.669 68.967 9.519 1.00 131.30 ? 68 ASN A CA 1 ATOM 242 C C . ASN A 1 44 ? 14.253 69.527 9.375 1.00 125.50 ? 68 ASN A C 1 ATOM 243 O O . ASN A 1 44 ? 13.975 70.244 8.392 1.00 134.69 ? 68 ASN A O 1 ATOM 244 C CB . ASN A 1 44 ? 15.779 67.456 9.398 1.00 115.76 ? 68 ASN A CB 1 ATOM 245 C CG . ASN A 1 44 ? 15.650 66.992 7.951 1.00 113.95 ? 68 ASN A CG 1 ATOM 246 O OD1 . ASN A 1 44 ? 15.458 65.810 7.691 1.00 112.65 ? 68 ASN A OD1 1 ATOM 247 N ND2 . ASN A 1 44 ? 15.759 67.931 7.000 1.00 113.11 ? 68 ASN A ND2 1 ATOM 248 N N . PRO A 1 45 ? 13.315 69.085 10.249 1.00 106.45 ? 69 PRO A N 1 ATOM 249 C CA . PRO A 1 45 ? 12.005 69.731 10.130 1.00 98.79 ? 69 PRO A CA 1 ATOM 250 C C . PRO A 1 45 ? 12.222 71.024 11.010 1.00 99.44 ? 69 PRO A C 1 ATOM 251 O O . PRO A 1 45 ? 12.877 70.978 12.069 1.00 95.51 ? 69 PRO A O 1 ATOM 252 C CB . PRO A 1 45 ? 11.052 68.803 10.876 1.00 78.99 ? 69 PRO A CB 1 ATOM 253 C CG . PRO A 1 45 ? 11.736 67.465 10.877 1.00 76.55 ? 69 PRO A CG 1 ATOM 254 C CD . PRO A 1 45 ? 13.201 67.790 10.965 1.00 81.84 ? 69 PRO A CD 1 ATOM 255 N N . ALA A 1 46 ? 11.685 72.159 10.559 1.00 129.26 ? 70 ALA A N 1 ATOM 256 C CA . ALA A 1 46 ? 11.756 73.426 11.309 1.00 139.19 ? 70 ALA A CA 1 ATOM 257 C C . ALA A 1 46 ? 11.146 73.163 12.694 1.00 144.18 ? 70 ALA A C 1 ATOM 258 O O . ALA A 1 46 ? 9.974 72.780 12.819 1.00 152.17 ? 70 ALA A O 1 ATOM 259 C CB . ALA A 1 46 ? 11.009 74.523 10.564 1.00 113.57 ? 70 ALA A CB 1 ATOM 260 N N . PRO A 1 47 ? 11.938 73.402 13.753 1.00 110.86 ? 71 PRO A N 1 ATOM 261 C CA . PRO A 1 47 ? 11.483 73.157 15.121 1.00 108.41 ? 71 PRO A CA 1 ATOM 262 C C . PRO A 1 47 ? 10.398 74.055 15.647 1.00 103.42 ? 71 PRO A C 1 ATOM 263 O O . PRO A 1 47 ? 10.302 75.201 15.225 1.00 98.69 ? 71 PRO A O 1 ATOM 264 C CB . PRO A 1 47 ? 12.774 73.277 15.939 1.00 109.21 ? 71 PRO A CB 1 ATOM 265 C CG . PRO A 1 47 ? 13.561 74.306 15.206 1.00 111.32 ? 71 PRO A CG 1 ATOM 266 C CD . PRO A 1 47 ? 13.221 74.141 13.739 1.00 114.44 ? 71 PRO A CD 1 ATOM 267 N N . SER A 1 48 ? 9.577 73.522 16.556 1.00 91.76 ? 72 SER A N 1 ATOM 268 C CA . SER A 1 48 ? 8.533 74.313 17.216 1.00 87.18 ? 72 SER A CA 1 ATOM 269 C C . SER A 1 48 ? 9.052 74.689 18.607 1.00 81.58 ? 72 SER A C 1 ATOM 270 O O . SER A 1 48 ? 9.804 73.933 19.226 1.00 80.57 ? 72 SER A O 1 ATOM 271 C CB . SER A 1 48 ? 7.219 73.540 17.309 1.00 106.40 ? 72 SER A CB 1 ATOM 272 O OG . SER A 1 48 ? 7.345 72.368 18.095 1.00 109.65 ? 72 SER A OG 1 ATOM 273 N N . PHE A 1 49 ? 8.626 75.845 19.092 1.00 80.08 ? 73 PHE A N 1 ATOM 274 C CA . PHE A 1 49 ? 9.142 76.390 20.338 1.00 73.55 ? 73 PHE A CA 1 ATOM 275 C C . PHE A 1 49 ? 8.112 76.662 21.411 1.00 69.94 ? 73 PHE A C 1 ATOM 276 O O . PHE A 1 49 ? 6.973 77.017 21.114 1.00 66.76 ? 73 PHE A O 1 ATOM 277 C CB . PHE A 1 49 ? 9.850 77.738 20.051 1.00 81.58 ? 73 PHE A CB 1 ATOM 278 C CG . PHE A 1 49 ? 10.965 77.654 19.046 1.00 88.17 ? 73 PHE A CG 1 ATOM 279 C CD1 . PHE A 1 49 ? 10.697 77.651 17.677 1.00 91.66 ? 73 PHE A CD1 1 ATOM 280 C CD2 . PHE A 1 49 ? 12.288 77.585 19.474 1.00 91.52 ? 73 PHE A CD2 1 ATOM 281 C CE1 . PHE A 1 49 ? 11.733 77.574 16.745 1.00 93.38 ? 73 PHE A CE1 1 ATOM 282 C CE2 . PHE A 1 49 ? 13.336 77.506 18.555 1.00 93.23 ? 73 PHE A CE2 1 ATOM 283 C CZ . PHE A 1 49 ? 13.058 77.504 17.186 1.00 93.78 ? 73 PHE A CZ 1 ATOM 284 N N . HIS A 1 50 ? 8.523 76.456 22.660 1.00 61.41 ? 74 HIS A N 1 ATOM 285 C CA . HIS A 1 50 ? 7.720 76.850 23.809 1.00 58.68 ? 74 HIS A CA 1 ATOM 286 C C . HIS A 1 50 ? 8.665 77.273 24.941 1.00 57.63 ? 74 HIS A C 1 ATOM 287 O O . HIS A 1 50 ? 9.860 76.969 24.918 1.00 52.95 ? 74 HIS A O 1 ATOM 288 C CB . HIS A 1 50 ? 6.729 75.788 24.252 1.00 69.28 ? 74 HIS A CB 1 ATOM 289 C CG . HIS A 1 50 ? 7.356 74.575 24.845 1.00 74.59 ? 74 HIS A CG 1 ATOM 290 N ND1 . HIS A 1 50 ? 7.719 73.480 24.090 1.00 77.60 ? 74 HIS A ND1 1 ATOM 291 C CD2 . HIS A 1 50 ? 7.670 74.275 26.127 1.00 76.19 ? 74 HIS A CD2 1 ATOM 292 C CE1 . HIS A 1 50 ? 8.229 72.555 24.884 1.00 78.33 ? 74 HIS A CE1 1 ATOM 293 N NE2 . HIS A 1 50 ? 8.211 73.013 26.125 1.00 77.07 ? 74 HIS A NE2 1 ATOM 294 N N . TRP A 1 51 ? 8.111 77.959 25.930 1.00 59.31 ? 75 TRP A N 1 ATOM 295 C CA . TRP A 1 51 ? 8.896 78.540 26.993 1.00 59.71 ? 75 TRP A CA 1 ATOM 296 C C . TRP A 1 51 ? 8.401 78.248 28.382 1.00 57.81 ? 75 TRP A C 1 ATOM 297 O O . TRP A 1 51 ? 7.229 77.935 28.571 1.00 57.43 ? 75 TRP A O 1 ATOM 298 C CB . TRP A 1 51 ? 8.880 80.070 26.816 1.00 69.69 ? 75 TRP A CB 1 ATOM 299 C CG . TRP A 1 51 ? 9.726 80.546 25.706 1.00 76.40 ? 75 TRP A CG 1 ATOM 300 C CD1 . TRP A 1 51 ? 9.418 80.548 24.382 1.00 78.68 ? 75 TRP A CD1 1 ATOM 301 C CD2 . TRP A 1 51 ? 11.049 81.069 25.815 1.00 79.73 ? 75 TRP A CD2 1 ATOM 302 N NE1 . TRP A 1 51 ? 10.467 81.041 23.653 1.00 79.96 ? 75 TRP A NE1 1 ATOM 303 C CE2 . TRP A 1 51 ? 11.485 81.368 24.507 1.00 80.97 ? 75 TRP A CE2 1 ATOM 304 C CE3 . TRP A 1 51 ? 11.913 81.312 26.891 1.00 80.53 ? 75 TRP A CE3 1 ATOM 305 C CZ2 . TRP A 1 51 ? 12.752 81.906 24.242 1.00 80.67 ? 75 TRP A CZ2 1 ATOM 306 C CZ3 . TRP A 1 51 ? 13.168 81.846 26.627 1.00 81.17 ? 75 TRP A CZ3 1 ATOM 307 C CH2 . TRP A 1 51 ? 13.575 82.136 25.311 1.00 81.02 ? 75 TRP A CH2 1 ATOM 308 N N . THR A 1 52 ? 9.318 78.315 29.343 1.00 55.90 ? 76 THR A N 1 ATOM 309 C CA . THR A 1 52 ? 8.929 78.246 30.737 1.00 58.27 ? 76 THR A CA 1 ATOM 310 C C . THR A 1 52 ? 9.319 79.569 31.388 1.00 61.45 ? 76 THR A C 1 ATOM 311 O O . THR A 1 52 ? 10.317 80.197 31.012 1.00 60.35 ? 76 THR A O 1 ATOM 312 C CB . THR A 1 52 ? 9.624 77.121 31.559 1.00 61.95 ? 76 THR A CB 1 ATOM 313 O OG1 . THR A 1 52 ? 11.040 77.343 31.613 1.00 61.76 ? 76 THR A OG1 1 ATOM 314 C CG2 . THR A 1 52 ? 9.313 75.766 30.963 1.00 59.77 ? 76 THR A CG2 1 ATOM 315 N N . ARG A 1 53 ? 8.493 80.004 32.335 1.00 57.00 ? 77 ARG A N 1 ATOM 316 C CA . ARG A 1 53 ? 8.804 81.185 33.131 1.00 58.80 ? 77 ARG A CA 1 ATOM 317 C C . ARG A 1 53 ? 8.721 80.679 34.572 1.00 57.77 ? 77 ARG A C 1 ATOM 318 O O . ARG A 1 53 ? 7.680 80.208 35.011 1.00 53.63 ? 77 ARG A O 1 ATOM 319 C CB . ARG A 1 53 ? 7.814 82.313 32.887 1.00 81.67 ? 77 ARG A CB 1 ATOM 320 C CG . ARG A 1 53 ? 8.327 83.678 33.330 1.00 95.85 ? 77 ARG A CG 1 ATOM 321 C CD . ARG A 1 53 ? 7.210 84.717 33.355 1.00 103.19 ? 77 ARG A CD 1 ATOM 322 N NE . ARG A 1 53 ? 6.137 84.353 34.284 1.00 106.67 ? 77 ARG A NE 1 ATOM 323 C CZ . ARG A 1 53 ? 5.990 84.847 35.512 1.00 107.36 ? 77 ARG A CZ 1 ATOM 324 N NH1 . ARG A 1 53 ? 6.846 85.745 35.991 1.00 107.20 ? 77 ARG A NH1 1 ATOM 325 N NH2 . ARG A 1 53 ? 4.973 84.442 36.263 1.00 108.03 ? 77 ARG A NH2 1 ATOM 326 N N . ASN A 1 54 ? 9.840 80.771 35.284 1.00 70.21 ? 78 ASN A N 1 ATOM 327 C CA . ASN A 1 54 ? 9.961 80.267 36.647 1.00 73.54 ? 78 ASN A CA 1 ATOM 328 C C . ASN A 1 54 ? 9.451 78.824 36.801 1.00 74.16 ? 78 ASN A C 1 ATOM 329 O O . ASN A 1 54 ? 8.648 78.527 37.690 1.00 75.00 ? 78 ASN A O 1 ATOM 330 C CB . ASN A 1 54 ? 9.287 81.207 37.655 1.00 76.90 ? 78 ASN A CB 1 ATOM 331 C CG . ASN A 1 54 ? 9.890 82.604 37.632 1.00 79.51 ? 78 ASN A CG 1 ATOM 332 O OD1 . ASN A 1 54 ? 9.270 83.548 37.140 1.00 80.28 ? 78 ASN A OD1 1 ATOM 333 N ND2 . ASN A 1 54 ? 11.112 82.738 38.148 1.00 79.62 ? 78 ASN A ND2 1 ATOM 334 N N . SER A 1 55 ? 9.931 77.948 35.907 1.00 66.86 ? 79 SER A N 1 ATOM 335 C CA . SER A 1 55 ? 9.622 76.502 35.916 1.00 66.70 ? 79 SER A CA 1 ATOM 336 C C . SER A 1 55 ? 8.223 76.044 35.561 1.00 66.65 ? 79 SER A C 1 ATOM 337 O O . SER A 1 55 ? 7.942 74.842 35.621 1.00 62.92 ? 79 SER A O 1 ATOM 338 C CB . SER A 1 55 ? 9.838 75.886 37.293 1.00 76.33 ? 79 SER A CB 1 ATOM 339 O OG . SER A 1 55 ? 11.202 75.718 37.596 1.00 81.71 ? 79 SER A OG 1 ATOM 340 N N . ARG A 1 56 ? 7.326 76.971 35.259 1.00 70.51 ? 80 ARG A N 1 ATOM 341 C CA . ARG A 1 56 ? 5.963 76.587 34.902 1.00 73.32 ? 80 ARG A CA 1 ATOM 342 C C . ARG A 1 56 ? 5.807 77.042 33.471 1.00 67.75 ? 80 ARG A C 1 ATOM 343 O O . ARG A 1 56 ? 6.468 77.986 33.042 1.00 62.39 ? 80 ARG A O 1 ATOM 344 C CB . ARG A 1 56 ? 4.859 77.209 35.790 1.00 111.37 ? 80 ARG A CB 1 ATOM 345 C CG . ARG A 1 56 ? 4.501 76.339 36.992 1.00 135.24 ? 80 ARG A CG 1 ATOM 346 C CD . ARG A 1 56 ? 3.330 76.906 37.786 1.00 147.06 ? 80 ARG A CD 1 ATOM 347 N NE . ARG A 1 56 ? 2.983 76.034 38.908 1.00 150.95 ? 80 ARG A NE 1 ATOM 348 C CZ . ARG A 1 56 ? 2.244 76.398 39.955 1.00 152.09 ? 80 ARG A CZ 1 ATOM 349 N NH1 . ARG A 1 56 ? 1.758 77.634 40.046 1.00 152.13 ? 80 ARG A NH1 1 ATOM 350 N NH2 . ARG A 1 56 ? 1.994 75.519 40.918 1.00 152.18 ? 80 ARG A NH2 1 ATOM 351 N N . PHE A 1 57 ? 4.959 76.336 32.727 1.00 71.89 ? 81 PHE A N 1 ATOM 352 C CA . PHE A 1 57 ? 4.702 76.634 31.320 1.00 71.12 ? 81 PHE A CA 1 ATOM 353 C C . PHE A 1 57 ? 4.275 78.087 31.131 1.00 69.63 ? 81 PHE A C 1 ATOM 354 O O . PHE A 1 57 ? 3.319 78.563 31.760 1.00 69.74 ? 81 PHE A O 1 ATOM 355 C CB . PHE A 1 57 ? 3.632 75.679 30.763 1.00 73.64 ? 81 PHE A CB 1 ATOM 356 C CG . PHE A 1 57 ? 3.190 76.007 29.357 1.00 76.32 ? 81 PHE A CG 1 ATOM 357 C CD1 . PHE A 1 57 ? 4.074 75.898 28.282 1.00 77.70 ? 81 PHE A CD1 1 ATOM 358 C CD2 . PHE A 1 57 ? 1.886 76.427 29.108 1.00 77.48 ? 81 PHE A CD2 1 ATOM 359 C CE1 . PHE A 1 57 ? 3.666 76.207 26.982 1.00 77.41 ? 81 PHE A CE1 1 ATOM 360 C CE2 . PHE A 1 57 ? 1.471 76.740 27.809 1.00 76.96 ? 81 PHE A CE2 1 ATOM 361 C CZ . PHE A 1 57 ? 2.360 76.628 26.748 1.00 76.31 ? 81 PHE A CZ 1 ATOM 362 N N . PHE A 1 58 ? 5.003 78.790 30.270 1.00 63.53 ? 82 PHE A N 1 ATOM 363 C CA . PHE A 1 58 ? 4.724 80.195 30.007 1.00 70.91 ? 82 PHE A CA 1 ATOM 364 C C . PHE A 1 58 ? 3.728 80.314 28.855 1.00 78.01 ? 82 PHE A C 1 ATOM 365 O O . PHE A 1 58 ? 4.080 80.158 27.678 1.00 68.91 ? 82 PHE A O 1 ATOM 366 C CB . PHE A 1 58 ? 6.026 80.953 29.703 1.00 78.43 ? 82 PHE A CB 1 ATOM 367 C CG . PHE A 1 58 ? 5.854 82.447 29.603 1.00 81.91 ? 82 PHE A CG 1 ATOM 368 C CD1 . PHE A 1 58 ? 6.406 83.148 28.532 1.00 83.80 ? 82 PHE A CD1 1 ATOM 369 C CD2 . PHE A 1 58 ? 5.147 83.156 30.575 1.00 82.88 ? 82 PHE A CD2 1 ATOM 370 C CE1 . PHE A 1 58 ? 6.257 84.532 28.426 1.00 82.73 ? 82 PHE A CE1 1 ATOM 371 C CE2 . PHE A 1 58 ? 4.995 84.537 30.475 1.00 82.64 ? 82 PHE A CE2 1 ATOM 372 C CZ . PHE A 1 58 ? 5.553 85.223 29.398 1.00 82.05 ? 82 PHE A CZ 1 ATOM 373 N N . ASN A 1 59 ? 2.476 80.593 29.225 1.00 101.62 ? 83 ASN A N 1 ATOM 374 C CA . ASN A 1 59 ? 1.363 80.695 28.280 1.00 111.37 ? 83 ASN A CA 1 ATOM 375 C C . ASN A 1 59 ? 1.401 82.003 27.481 1.00 115.72 ? 83 ASN A C 1 ATOM 376 O O . ASN A 1 59 ? 1.016 83.061 27.991 1.00 128.19 ? 83 ASN A O 1 ATOM 377 C CB . ASN A 1 59 ? 0.041 80.582 29.052 1.00 102.65 ? 83 ASN A CB 1 ATOM 378 C CG . ASN A 1 59 ? -1.017 79.792 28.299 1.00 94.66 ? 83 ASN A CG 1 ATOM 379 O OD1 . ASN A 1 59 ? -1.035 79.763 27.064 1.00 89.84 ? 83 ASN A OD1 1 ATOM 380 N ND2 . ASN A 1 59 ? -1.916 79.157 29.047 1.00 90.68 ? 83 ASN A ND2 1 ATOM 381 N N . ILE A 1 60 ? 1.870 81.921 26.231 1.00 110.79 ? 84 ILE A N 1 ATOM 382 C CA . ILE A 1 60 ? 1.991 83.102 25.357 1.00 105.47 ? 84 ILE A CA 1 ATOM 383 C C . ILE A 1 60 ? 0.596 83.650 25.067 1.00 101.71 ? 84 ILE A C 1 ATOM 384 O O . ILE A 1 60 ? 0.326 84.828 25.312 1.00 95.28 ? 84 ILE A O 1 ATOM 385 C CB . ILE A 1 60 ? 2.738 82.773 24.036 1.00 99.17 ? 84 ILE A CB 1 ATOM 386 C CG1 . ILE A 1 60 ? 4.138 82.202 24.334 1.00 103.60 ? 84 ILE A CG1 1 ATOM 387 C CG2 . ILE A 1 60 ? 2.822 84.025 23.156 1.00 105.44 ? 84 ILE A CG2 1 ATOM 388 C CD1 . ILE A 1 60 ? 5.120 83.115 25.109 1.00 101.61 ? 84 ILE A CD1 1 ATOM 389 N N . ALA A 1 61 ? -0.276 82.796 24.535 1.00 108.46 ? 85 ALA A N 1 ATOM 390 C CA . ALA A 1 61 ? -1.665 83.186 24.310 1.00 116.87 ? 85 ALA A CA 1 ATOM 391 C C . ALA A 1 61 ? -2.619 84.048 25.190 1.00 120.33 ? 85 ALA A C 1 ATOM 392 O O . ALA A 1 61 ? -3.449 84.762 24.618 1.00 131.97 ? 85 ALA A O 1 ATOM 393 C CB . ALA A 1 61 ? -2.420 81.985 23.711 1.00 105.33 ? 85 ALA A CB 1 ATOM 394 N N . LYS A 1 62 ? -2.433 84.080 26.492 1.00 102.49 ? 86 LYS A N 1 ATOM 395 C CA . LYS A 1 62 ? -3.279 84.751 27.455 1.00 93.11 ? 86 LYS A CA 1 ATOM 396 C C . LYS A 1 62 ? -2.516 86.043 27.850 1.00 91.56 ? 86 LYS A C 1 ATOM 397 O O . LYS A 1 62 ? -2.986 86.864 28.647 1.00 94.79 ? 86 LYS A O 1 ATOM 398 C CB . LYS A 1 62 ? -3.347 83.645 28.488 1.00 94.24 ? 86 LYS A CB 1 ATOM 399 C CG . LYS A 1 62 ? -4.624 82.809 28.447 1.00 86.25 ? 86 LYS A CG 1 ATOM 400 C CD . LYS A 1 62 ? -4.522 81.563 29.317 1.00 81.67 ? 86 LYS A CD 1 ATOM 401 C CE . LYS A 1 62 ? -5.827 80.773 29.295 1.00 81.39 ? 86 LYS A CE 1 ATOM 402 N NZ . LYS A 1 62 ? -5.774 79.528 30.115 1.00 81.58 ? 86 LYS A NZ 1 ATOM 403 N N . ASP A 1 63 ? -1.315 86.182 27.278 1.00 105.70 ? 87 ASP A N 1 ATOM 404 C CA . ASP A 1 63 ? -0.492 87.389 27.440 1.00 103.35 ? 87 ASP A CA 1 ATOM 405 C C . ASP A 1 63 ? -0.498 88.215 26.126 1.00 98.25 ? 87 ASP A C 1 ATOM 406 O O . ASP A 1 63 ? -0.063 87.737 25.070 1.00 94.61 ? 87 ASP A O 1 ATOM 407 C CB . ASP A 1 63 ? 0.917 86.984 27.827 1.00 115.85 ? 87 ASP A CB 1 ATOM 408 C CG . ASP A 1 63 ? 1.753 88.154 28.318 1.00 124.80 ? 87 ASP A CG 1 ATOM 409 O OD1 . ASP A 1 63 ? 1.818 89.188 27.614 1.00 128.67 ? 87 ASP A OD1 1 ATOM 410 O OD2 . ASP A 1 63 ? 2.360 88.033 29.404 1.00 128.14 ? 87 ASP A OD2 1 ATOM 411 N N . PRO A 1 64 ? -0.973 89.475 26.198 1.00 101.23 ? 88 PRO A N 1 ATOM 412 C CA . PRO A 1 64 ? -1.057 90.364 25.033 1.00 103.38 ? 88 PRO A CA 1 ATOM 413 C C . PRO A 1 64 ? 0.248 90.954 24.570 1.00 107.51 ? 88 PRO A C 1 ATOM 414 O O . PRO A 1 64 ? 0.409 91.291 23.396 1.00 111.05 ? 88 PRO A O 1 ATOM 415 C CB . PRO A 1 64 ? -2.001 91.485 25.498 1.00 75.48 ? 88 PRO A CB 1 ATOM 416 C CG . PRO A 1 64 ? -2.396 91.140 26.925 1.00 71.63 ? 88 PRO A CG 1 ATOM 417 C CD . PRO A 1 64 ? -1.374 90.179 27.430 1.00 76.76 ? 88 PRO A CD 1 ATOM 418 N N . ARG A 1 65 ? 1.173 91.067 25.514 1.00 87.28 ? 89 ARG A N 1 ATOM 419 C CA . ARG A 1 65 ? 2.448 91.722 25.285 1.00 85.71 ? 89 ARG A CA 1 ATOM 420 C C . ARG A 1 65 ? 3.438 90.924 24.448 1.00 83.47 ? 89 ARG A C 1 ATOM 421 O O . ARG A 1 65 ? 4.086 91.465 23.543 1.00 76.87 ? 89 ARG A O 1 ATOM 422 C CB . ARG A 1 65 ? 3.086 92.058 26.650 1.00 98.74 ? 89 ARG A CB 1 ATOM 423 C CG . ARG A 1 65 ? 2.102 92.566 27.727 1.00 107.10 ? 89 ARG A CG 1 ATOM 424 C CD . ARG A 1 65 ? 2.029 94.096 27.772 1.00 111.34 ? 89 ARG A CD 1 ATOM 425 N NE . ARG A 1 65 ? 1.113 94.662 28.775 1.00 113.09 ? 89 ARG A NE 1 ATOM 426 C CZ . ARG A 1 65 ? 0.880 94.179 30.000 1.00 113.53 ? 89 ARG A CZ 1 ATOM 427 N NH1 . ARG A 1 65 ? 1.482 93.078 30.436 1.00 113.70 ? 89 ARG A NH1 1 ATOM 428 N NH2 . ARG A 1 65 ? 0.032 94.815 30.802 1.00 113.53 ? 89 ARG A NH2 1 ATOM 429 N N . VAL A 1 66 ? 3.512 89.624 24.727 1.00 78.58 ? 90 VAL A N 1 ATOM 430 C CA . VAL A 1 66 ? 4.508 88.757 24.103 1.00 78.63 ? 90 VAL A CA 1 ATOM 431 C C . VAL A 1 66 ? 4.041 88.079 22.825 1.00 76.45 ? 90 VAL A C 1 ATOM 432 O O . VAL A 1 66 ? 2.854 87.822 22.659 1.00 72.82 ? 90 VAL A O 1 ATOM 433 C CB . VAL A 1 66 ? 4.987 87.679 25.129 1.00 86.36 ? 90 VAL A CB 1 ATOM 434 C CG1 . VAL A 1 66 ? 6.398 87.226 24.801 1.00 93.71 ? 90 VAL A CG1 1 ATOM 435 C CG2 . VAL A 1 66 ? 4.935 88.232 26.547 1.00 93.36 ? 90 VAL A CG2 1 ATOM 436 N N . SER A 1 67 ? 4.985 87.804 21.926 1.00 81.43 ? 91 SER A N 1 ATOM 437 C CA . SER A 1 67 ? 4.694 87.160 20.644 1.00 83.44 ? 91 SER A CA 1 ATOM 438 C C . SER A 1 67 ? 5.923 86.446 20.070 1.00 82.75 ? 91 SER A C 1 ATOM 439 O O . SER A 1 67 ? 7.055 86.856 20.315 1.00 81.19 ? 91 SER A O 1 ATOM 440 C CB . SER A 1 67 ? 4.186 88.198 19.629 1.00 90.67 ? 91 SER A CB 1 ATOM 441 O OG . SER A 1 67 ? 5.176 89.172 19.334 1.00 95.81 ? 91 SER A OG 1 ATOM 442 N N . MET A 1 68 ? 5.693 85.379 19.305 1.00 84.40 ? 92 MET A N 1 ATOM 443 C CA . MET A 1 68 ? 6.780 84.621 18.700 1.00 84.10 ? 92 MET A CA 1 ATOM 444 C C . MET A 1 68 ? 7.178 85.187 17.340 1.00 84.73 ? 92 MET A C 1 ATOM 445 O O . MET A 1 68 ? 6.591 86.158 16.877 1.00 82.19 ? 92 MET A O 1 ATOM 446 C CB . MET A 1 68 ? 6.459 83.125 18.657 1.00 87.35 ? 92 MET A CB 1 ATOM 447 C CG . MET A 1 68 ? 7.661 82.243 18.988 1.00 93.31 ? 92 MET A CG 1 ATOM 448 S SD . MET A 1 68 ? 7.250 80.559 19.463 1.00 95.32 ? 92 MET A SD 1 ATOM 449 C CE . MET A 1 68 ? 7.253 79.728 17.867 1.00 96.50 ? 92 MET A CE 1 ATOM 450 N N . ARG A 1 69 ? 8.143 84.550 16.691 1.00 74.44 ? 93 ARG A N 1 ATOM 451 C CA . ARG A 1 69 ? 8.785 85.135 15.516 1.00 82.94 ? 93 ARG A CA 1 ATOM 452 C C . ARG A 1 69 ? 8.651 84.361 14.216 1.00 87.80 ? 93 ARG A C 1 ATOM 453 O O . ARG A 1 69 ? 8.012 83.312 14.169 1.00 80.38 ? 93 ARG A O 1 ATOM 454 C CB . ARG A 1 69 ? 10.296 85.284 15.865 1.00 111.05 ? 93 ARG A CB 1 ATOM 455 C CG . ARG A 1 69 ? 10.987 86.546 15.347 1.00 121.40 ? 93 ARG A CG 1 ATOM 456 C CD . ARG A 1 69 ? 11.083 87.635 16.418 1.00 126.37 ? 93 ARG A CD 1 ATOM 457 N NE . ARG A 1 69 ? 11.382 88.956 15.859 1.00 128.19 ? 93 ARG A NE 1 ATOM 458 C CZ . ARG A 1 69 ? 12.587 89.374 15.473 1.00 128.75 ? 93 ARG A CZ 1 ATOM 459 N NH1 . ARG A 1 69 ? 13.649 88.581 15.579 1.00 128.56 ? 93 ARG A NH1 1 ATOM 460 N NH2 . ARG A 1 69 ? 12.730 90.598 14.976 1.00 128.56 ? 93 ARG A NH2 1 ATOM 461 N N . ARG A 1 70 ? 9.241 84.916 13.158 1.00 129.30 ? 94 ARG A N 1 ATOM 462 C CA . ARG A 1 70 ? 9.302 84.259 11.862 1.00 142.04 ? 94 ARG A CA 1 ATOM 463 C C . ARG A 1 70 ? 10.153 82.990 12.009 1.00 148.97 ? 94 ARG A C 1 ATOM 464 O O . ARG A 1 70 ? 11.364 83.072 12.232 1.00 162.94 ? 94 ARG A O 1 ATOM 465 C CB . ARG A 1 70 ? 9.995 85.151 10.811 1.00 125.08 ? 94 ARG A CB 1 ATOM 466 C CG . ARG A 1 70 ? 9.437 86.559 10.635 1.00 115.31 ? 94 ARG A CG 1 ATOM 467 C CD . ARG A 1 70 ? 10.269 87.587 11.391 1.00 109.64 ? 94 ARG A CD 1 ATOM 468 N NE . ARG A 1 70 ? 9.692 87.923 12.691 1.00 107.45 ? 94 ARG A NE 1 ATOM 469 C CZ . ARG A 1 70 ? 8.875 88.951 12.913 1.00 107.18 ? 94 ARG A CZ 1 ATOM 470 N NH1 . ARG A 1 70 ? 8.529 89.763 11.921 1.00 108.10 ? 94 ARG A NH1 1 ATOM 471 N NH2 . ARG A 1 70 ? 8.404 89.171 14.133 1.00 106.77 ? 94 ARG A NH2 1 ATOM 472 N N . ARG A 1 71 ? 9.510 81.830 11.915 1.00 123.43 ? 95 ARG A N 1 ATOM 473 C CA . ARG A 1 71 ? 10.197 80.532 11.930 1.00 118.46 ? 95 ARG A CA 1 ATOM 474 C C . ARG A 1 71 ? 11.152 80.279 13.110 1.00 115.74 ? 95 ARG A C 1 ATOM 475 O O . ARG A 1 71 ? 11.994 79.373 13.050 1.00 111.31 ? 95 ARG A O 1 ATOM 476 C CB . ARG A 1 71 ? 10.972 80.352 10.603 1.00 148.93 ? 95 ARG A CB 1 ATOM 477 C CG . ARG A 1 71 ? 10.218 80.752 9.332 1.00 150.13 ? 95 ARG A CG 1 ATOM 478 C CD . ARG A 1 71 ? 11.192 81.237 8.256 1.00 151.31 ? 95 ARG A CD 1 ATOM 479 N NE . ARG A 1 71 ? 12.022 80.157 7.721 1.00 152.29 ? 95 ARG A NE 1 ATOM 480 C CZ . ARG A 1 71 ? 13.260 80.310 7.252 1.00 152.48 ? 95 ARG A CZ 1 ATOM 481 N NH1 . ARG A 1 71 ? 13.839 81.506 7.248 1.00 152.31 ? 95 ARG A NH1 1 ATOM 482 N NH2 . ARG A 1 71 ? 13.923 79.259 6.785 1.00 152.60 ? 95 ARG A NH2 1 ATOM 483 N N . SER A 1 72 ? 11.026 81.076 14.173 1.00 150.37 ? 96 SER A N 1 ATOM 484 C CA . SER A 1 72 ? 11.862 80.903 15.365 1.00 146.36 ? 96 SER A CA 1 ATOM 485 C C . SER A 1 72 ? 11.065 81.057 16.675 1.00 144.25 ? 96 SER A C 1 ATOM 486 O O . SER A 1 72 ? 9.862 81.344 16.655 1.00 158.14 ? 96 SER A O 1 ATOM 487 C CB . SER A 1 72 ? 13.052 81.879 15.346 1.00 105.18 ? 96 SER A CB 1 ATOM 488 O OG . SER A 1 72 ? 12.755 83.088 16.024 1.00 88.85 ? 96 SER A OG 1 ATOM 489 N N . GLY A 1 73 ? 11.752 80.848 17.803 1.00 99.43 ? 97 GLY A N 1 ATOM 490 C CA . GLY A 1 73 ? 11.143 80.941 19.122 1.00 80.18 ? 97 GLY A CA 1 ATOM 491 C C . GLY A 1 73 ? 11.491 82.215 19.862 1.00 74.41 ? 97 GLY A C 1 ATOM 492 O O . GLY A 1 73 ? 11.096 82.401 21.017 1.00 65.99 ? 97 GLY A O 1 ATOM 493 N N . THR A 1 74 ? 12.248 83.085 19.197 1.00 81.54 ? 98 THR A N 1 ATOM 494 C CA . THR A 1 74 ? 12.619 84.383 19.750 1.00 85.52 ? 98 THR A CA 1 ATOM 495 C C . THR A 1 74 ? 11.347 85.124 20.132 1.00 85.85 ? 98 THR A C 1 ATOM 496 O O . THR A 1 74 ? 10.441 85.282 19.320 1.00 88.79 ? 98 THR A O 1 ATOM 497 C CB . THR A 1 74 ? 13.400 85.216 18.711 1.00 82.91 ? 98 THR A CB 1 ATOM 498 O OG1 . THR A 1 74 ? 14.625 84.546 18.404 1.00 84.09 ? 98 THR A OG1 1 ATOM 499 C CG2 . THR A 1 74 ? 13.704 86.610 19.242 1.00 81.88 ? 98 THR A CG2 1 ATOM 500 N N . LEU A 1 75 ? 11.278 85.558 21.381 1.00 77.97 ? 99 LEU A N 1 ATOM 501 C CA . LEU A 1 75 ? 10.113 86.274 21.862 1.00 78.36 ? 99 LEU A CA 1 ATOM 502 C C . LEU A 1 75 ? 10.323 87.775 21.763 1.00 81.51 ? 99 LEU A C 1 ATOM 503 O O . LEU A 1 75 ? 11.449 88.246 21.583 1.00 75.11 ? 99 LEU A O 1 ATOM 504 C CB . LEU A 1 75 ? 9.825 85.902 23.327 1.00 82.42 ? 99 LEU A CB 1 ATOM 505 C CG . LEU A 1 75 ? 9.614 84.415 23.667 1.00 84.97 ? 99 LEU A CG 1 ATOM 506 C CD1 . LEU A 1 75 ? 9.260 84.284 25.144 1.00 86.07 ? 99 LEU A CD1 1 ATOM 507 C CD2 . LEU A 1 75 ? 8.529 83.787 22.797 1.00 85.18 ? 99 LEU A CD2 1 ATOM 508 N N . VAL A 1 76 ? 9.216 88.512 21.833 1.00 104.09 ? 100 VAL A N 1 ATOM 509 C CA . VAL A 1 76 ? 9.224 89.974 21.864 1.00 106.69 ? 100 VAL A CA 1 ATOM 510 C C . VAL A 1 76 ? 8.041 90.484 22.681 1.00 110.76 ? 100 VAL A C 1 ATOM 511 O O . VAL A 1 76 ? 6.891 90.150 22.409 1.00 122.99 ? 100 VAL A O 1 ATOM 512 C CB . VAL A 1 76 ? 9.252 90.626 20.432 1.00 92.10 ? 100 VAL A CB 1 ATOM 513 C CG1 . VAL A 1 76 ? 8.354 89.883 19.471 1.00 83.90 ? 100 VAL A CG1 1 ATOM 514 C CG2 . VAL A 1 76 ? 8.878 92.111 20.512 1.00 82.54 ? 100 VAL A CG2 1 ATOM 515 N N . ILE A 1 77 ? 8.347 91.261 23.715 1.00 88.84 ? 101 ILE A N 1 ATOM 516 C CA . ILE A 1 77 ? 7.322 91.839 24.574 1.00 85.78 ? 101 ILE A CA 1 ATOM 517 C C . ILE A 1 77 ? 7.040 93.273 24.074 1.00 91.67 ? 101 ILE A C 1 ATOM 518 O O . ILE A 1 77 ? 7.805 93.808 23.266 1.00 83.04 ? 101 ILE A O 1 ATOM 519 C CB . ILE A 1 77 ? 7.790 91.824 26.065 1.00 93.09 ? 101 ILE A CB 1 ATOM 520 C CG1 . ILE A 1 77 ? 8.428 90.464 26.383 1.00 93.30 ? 101 ILE A CG1 1 ATOM 521 C CG2 . ILE A 1 77 ? 6.607 92.084 27.006 1.00 95.41 ? 101 ILE A CG2 1 ATOM 522 C CD1 . ILE A 1 77 ? 9.236 90.420 27.678 1.00 87.61 ? 101 ILE A CD1 1 ATOM 523 N N . ASP A 1 78 ? 5.922 93.863 24.510 1.00 125.25 ? 102 ASP A N 1 ATOM 524 C CA . ASP A 1 78 ? 5.529 95.235 24.117 1.00 141.28 ? 102 ASP A CA 1 ATOM 525 C C . ASP A 1 78 ? 4.701 95.929 25.211 1.00 149.54 ? 102 ASP A C 1 ATOM 526 O O . ASP A 1 78 ? 3.605 95.480 25.562 1.00 160.11 ? 102 ASP A O 1 ATOM 527 C CB . ASP A 1 78 ? 4.752 95.222 22.791 1.00 151.77 ? 102 ASP A CB 1 ATOM 528 C CG . ASP A 1 78 ? 5.624 95.588 21.595 1.00 147.78 ? 102 ASP A CG 1 ATOM 529 O OD1 . ASP A 1 78 ? 5.203 95.311 20.453 1.00 145.42 ? 102 ASP A OD1 1 ATOM 530 O OD2 . ASP A 1 78 ? 6.719 96.162 21.791 1.00 145.62 ? 102 ASP A OD2 1 ATOM 531 N N . PHE A 1 79 ? 5.229 97.040 25.725 1.00 152.87 ? 103 PHE A N 1 ATOM 532 C CA . PHE A 1 79 ? 4.597 97.765 26.832 1.00 148.56 ? 103 PHE A CA 1 ATOM 533 C C . PHE A 1 79 ? 3.857 99.030 26.405 1.00 144.56 ? 103 PHE A C 1 ATOM 534 O O . PHE A 1 79 ? 3.394 99.801 27.253 1.00 144.86 ? 103 PHE A O 1 ATOM 535 C CB . PHE A 1 79 ? 5.668 98.106 27.891 1.00 152.82 ? 103 PHE A CB 1 ATOM 536 C CG . PHE A 1 79 ? 6.363 96.897 28.473 1.00 156.91 ? 103 PHE A CG 1 ATOM 537 C CD1 . PHE A 1 79 ? 5.847 96.254 29.595 1.00 158.29 ? 103 PHE A CD1 1 ATOM 538 C CD2 . PHE A 1 79 ? 7.528 96.395 27.888 1.00 158.29 ? 103 PHE A CD2 1 ATOM 539 C CE1 . PHE A 1 79 ? 6.480 95.131 30.127 1.00 158.95 ? 103 PHE A CE1 1 ATOM 540 C CE2 . PHE A 1 79 ? 8.166 95.274 28.411 1.00 159.00 ? 103 PHE A CE2 1 ATOM 541 C CZ . PHE A 1 79 ? 7.642 94.639 29.534 1.00 159.20 ? 103 PHE A CZ 1 ATOM 542 N N . ARG A 1 80 ? 3.727 99.217 25.091 1.00 144.37 ? 104 ARG A N 1 ATOM 543 C CA . ARG A 1 80 ? 3.063 100.388 24.505 1.00 144.48 ? 104 ARG A CA 1 ATOM 544 C C . ARG A 1 80 ? 1.586 100.520 24.891 1.00 147.84 ? 104 ARG A C 1 ATOM 545 O O . ARG A 1 80 ? 0.917 101.469 24.468 1.00 147.41 ? 104 ARG A O 1 ATOM 546 C CB . ARG A 1 80 ? 3.172 100.342 22.966 1.00 140.42 ? 104 ARG A CB 1 ATOM 547 C CG . ARG A 1 80 ? 4.576 100.532 22.410 1.00 132.12 ? 104 ARG A CG 1 ATOM 548 C CD . ARG A 1 80 ? 4.639 100.181 20.926 1.00 128.58 ? 104 ARG A CD 1 ATOM 549 N NE . ARG A 1 80 ? 5.983 100.360 20.371 1.00 128.26 ? 104 ARG A NE 1 ATOM 550 C CZ . ARG A 1 80 ? 6.389 99.900 19.185 1.00 128.25 ? 104 ARG A CZ 1 ATOM 551 N NH1 . ARG A 1 80 ? 5.558 99.218 18.401 1.00 127.80 ? 104 ARG A NH1 1 ATOM 552 N NH2 . ARG A 1 80 ? 7.636 100.121 18.780 1.00 127.63 ? 104 ARG A NH2 1 ATOM 553 N N . SER A 1 81 ? 1.094 99.587 25.707 1.00 176.39 ? 105 SER A N 1 ATOM 554 C CA . SER A 1 81 ? -0.316 99.557 26.098 1.00 181.80 ? 105 SER A CA 1 ATOM 555 C C . SER A 1 81 ? -0.564 99.327 27.600 1.00 187.28 ? 105 SER A C 1 ATOM 556 O O . SER A 1 81 ? -1.326 98.436 27.991 1.00 194.36 ? 105 SER A O 1 ATOM 557 C CB . SER A 1 81 ? -1.049 98.488 25.260 1.00 136.83 ? 105 SER A CB 1 ATOM 558 O OG . SER A 1 81 ? -2.450 98.533 25.469 1.00 118.74 ? 105 SER A OG 1 ATOM 559 N N . GLY A 1 82 ? 0.089 100.145 28.427 1.00 176.03 ? 106 GLY A N 1 ATOM 560 C CA . GLY A 1 82 ? -0.074 100.082 29.875 1.00 168.28 ? 106 GLY A CA 1 ATOM 561 C C . GLY A 1 82 ? 0.492 98.835 30.529 1.00 164.20 ? 106 GLY A C 1 ATOM 562 O O . GLY A 1 82 ? -0.262 97.974 30.984 1.00 163.32 ? 106 GLY A O 1 ATOM 563 N N . GLY A 1 83 ? 1.821 98.747 30.578 1.00 148.86 ? 107 GLY A N 1 ATOM 564 C CA . GLY A 1 83 ? 2.496 97.595 31.164 1.00 148.17 ? 107 GLY A CA 1 ATOM 565 C C . GLY A 1 83 ? 3.875 97.925 31.718 1.00 149.56 ? 107 GLY A C 1 ATOM 566 O O . GLY A 1 83 ? 4.533 98.857 31.246 1.00 144.73 ? 107 GLY A O 1 ATOM 567 N N . ARG A 1 84 ? 4.322 97.150 32.709 1.00 163.38 ? 108 ARG A N 1 ATOM 568 C CA . ARG A 1 84 ? 5.615 97.390 33.359 1.00 162.39 ? 108 ARG A CA 1 ATOM 569 C C . ARG A 1 84 ? 6.485 96.134 33.484 1.00 148.98 ? 108 ARG A C 1 ATOM 570 O O . ARG A 1 84 ? 6.044 95.107 34.010 1.00 162.10 ? 108 ARG A O 1 ATOM 571 C CB . ARG A 1 84 ? 5.392 98.069 34.729 1.00 177.24 ? 108 ARG A CB 1 ATOM 572 C CG . ARG A 1 84 ? 4.269 97.494 35.593 1.00 181.41 ? 108 ARG A CG 1 ATOM 573 C CD . ARG A 1 84 ? 3.881 98.477 36.707 1.00 182.55 ? 108 ARG A CD 1 ATOM 574 N NE . ARG A 1 84 ? 2.986 97.887 37.705 1.00 183.38 ? 108 ARG A NE 1 ATOM 575 C CZ . ARG A 1 84 ? 2.587 98.499 38.822 1.00 183.89 ? 108 ARG A CZ 1 ATOM 576 N NH1 . ARG A 1 84 ? 2.999 99.732 39.097 1.00 184.24 ? 108 ARG A NH1 1 ATOM 577 N NH2 . ARG A 1 84 ? 1.775 97.875 39.670 1.00 183.94 ? 108 ARG A NH2 1 ATOM 578 N N . PRO A 1 85 ? 7.749 96.215 33.000 1.00 98.81 ? 109 PRO A N 1 ATOM 579 C CA . PRO A 1 85 ? 8.713 95.102 33.025 1.00 87.00 ? 109 PRO A CA 1 ATOM 580 C C . PRO A 1 85 ? 9.107 94.598 34.403 1.00 84.47 ? 109 PRO A C 1 ATOM 581 O O . PRO A 1 85 ? 9.734 93.553 34.515 1.00 77.03 ? 109 PRO A O 1 ATOM 582 C CB . PRO A 1 85 ? 9.927 95.644 32.259 1.00 76.82 ? 109 PRO A CB 1 ATOM 583 C CG . PRO A 1 85 ? 9.445 96.886 31.567 1.00 75.08 ? 109 PRO A CG 1 ATOM 584 C CD . PRO A 1 85 ? 8.368 97.439 32.448 1.00 86.25 ? 109 PRO A CD 1 ATOM 585 N N . GLU A 1 86 ? 8.751 95.353 35.442 1.00 97.58 ? 110 GLU A N 1 ATOM 586 C CA . GLU A 1 86 ? 9.049 94.983 36.832 1.00 113.29 ? 110 GLU A CA 1 ATOM 587 C C . GLU A 1 86 ? 8.263 93.749 37.287 1.00 116.68 ? 110 GLU A C 1 ATOM 588 O O . GLU A 1 86 ? 8.657 93.074 38.242 1.00 111.76 ? 110 GLU A O 1 ATOM 589 C CB . GLU A 1 86 ? 8.793 96.171 37.769 1.00 148.72 ? 110 GLU A CB 1 ATOM 590 C CG . GLU A 1 86 ? 7.422 96.831 37.604 1.00 162.86 ? 110 GLU A CG 1 ATOM 591 C CD . GLU A 1 86 ? 7.374 98.249 38.159 1.00 168.45 ? 110 GLU A CD 1 ATOM 592 O OE1 . GLU A 1 86 ? 7.726 98.441 39.344 1.00 169.94 ? 110 GLU A OE1 1 ATOM 593 O OE2 . GLU A 1 86 ? 6.977 99.168 37.406 1.00 169.66 ? 110 GLU A OE2 1 ATOM 594 N N . GLU A 1 87 ? 7.153 93.467 36.604 1.00 148.98 ? 111 GLU A N 1 ATOM 595 C CA . GLU A 1 87 ? 6.350 92.270 36.870 1.00 156.04 ? 111 GLU A CA 1 ATOM 596 C C . GLU A 1 87 ? 6.877 91.098 36.017 1.00 153.89 ? 111 GLU A C 1 ATOM 597 O O . GLU A 1 87 ? 6.621 89.930 36.328 1.00 156.45 ? 111 GLU A O 1 ATOM 598 C CB . GLU A 1 87 ? 4.878 92.505 36.481 1.00 169.22 ? 111 GLU A CB 1 ATOM 599 C CG . GLU A 1 87 ? 4.191 93.661 37.201 1.00 175.15 ? 111 GLU A CG 1 ATOM 600 C CD . GLU A 1 87 ? 2.916 94.133 36.496 1.00 176.86 ? 111 GLU A CD 1 ATOM 601 O OE1 . GLU A 1 87 ? 2.014 94.660 37.187 1.00 177.03 ? 111 GLU A OE1 1 ATOM 602 O OE2 . GLU A 1 87 ? 2.816 93.993 35.255 1.00 176.84 ? 111 GLU A OE2 1 ATOM 603 N N . TYR A 1 88 ? 7.623 91.432 34.961 1.00 121.26 ? 112 TYR A N 1 ATOM 604 C CA . TYR A 1 88 ? 8.124 90.458 33.988 1.00 109.88 ? 112 TYR A CA 1 ATOM 605 C C . TYR A 1 88 ? 9.539 89.946 34.241 1.00 100.98 ? 112 TYR A C 1 ATOM 606 O O . TYR A 1 88 ? 10.230 89.497 33.323 1.00 95.41 ? 112 TYR A O 1 ATOM 607 C CB . TYR A 1 88 ? 8.001 91.061 32.574 1.00 117.34 ? 112 TYR A CB 1 ATOM 608 C CG . TYR A 1 88 ? 6.621 90.918 31.957 1.00 124.61 ? 112 TYR A CG 1 ATOM 609 C CD1 . TYR A 1 88 ? 5.465 91.069 32.732 1.00 128.10 ? 112 TYR A CD1 1 ATOM 610 C CD2 . TYR A 1 88 ? 6.470 90.622 30.601 1.00 128.17 ? 112 TYR A CD2 1 ATOM 611 C CE1 . TYR A 1 88 ? 4.200 90.923 32.178 1.00 129.66 ? 112 TYR A CE1 1 ATOM 612 C CE2 . TYR A 1 88 ? 5.207 90.480 30.036 1.00 129.92 ? 112 TYR A CE2 1 ATOM 613 C CZ . TYR A 1 88 ? 4.079 90.630 30.834 1.00 130.43 ? 112 TYR A CZ 1 ATOM 614 O OH . TYR A 1 88 ? 2.825 90.489 30.289 1.00 131.51 ? 112 TYR A OH 1 ATOM 615 N N . GLU A 1 89 ? 9.959 90.013 35.499 1.00 92.02 ? 113 GLU A N 1 ATOM 616 C CA . GLU A 1 89 ? 11.269 89.532 35.897 1.00 90.30 ? 113 GLU A CA 1 ATOM 617 C C . GLU A 1 89 ? 11.168 88.066 36.323 1.00 85.98 ? 113 GLU A C 1 ATOM 618 O O . GLU A 1 89 ? 10.347 87.714 37.178 1.00 82.76 ? 113 GLU A O 1 ATOM 619 C CB . GLU A 1 89 ? 11.832 90.370 37.061 1.00 104.97 ? 113 GLU A CB 1 ATOM 620 C CG . GLU A 1 89 ? 12.099 91.834 36.716 1.00 111.13 ? 113 GLU A CG 1 ATOM 621 C CD . GLU A 1 89 ? 13.056 92.512 37.688 1.00 113.91 ? 113 GLU A CD 1 ATOM 622 O OE1 . GLU A 1 89 ? 12.790 92.509 38.911 1.00 113.95 ? 113 GLU A OE1 1 ATOM 623 O OE2 . GLU A 1 89 ? 14.080 93.055 37.220 1.00 114.43 ? 113 GLU A OE2 1 ATOM 624 N N . GLY A 1 90 ? 12.001 87.220 35.711 1.00 86.82 ? 114 GLY A N 1 ATOM 625 C CA . GLY A 1 90 ? 12.017 85.808 36.048 1.00 81.89 ? 114 GLY A CA 1 ATOM 626 C C . GLY A 1 90 ? 12.947 84.960 35.200 1.00 77.38 ? 114 GLY A C 1 ATOM 627 O O . GLY A 1 90 ? 13.608 85.463 34.289 1.00 77.19 ? 114 GLY A O 1 ATOM 628 N N . GLU A 1 91 ? 12.973 83.662 35.508 1.00 71.03 ? 115 GLU A N 1 ATOM 629 C CA . GLU A 1 91 ? 13.810 82.683 34.821 1.00 68.50 ? 115 GLU A CA 1 ATOM 630 C C . GLU A 1 91 ? 13.099 82.109 33.593 1.00 62.90 ? 115 GLU A C 1 ATOM 631 O O . GLU A 1 91 ? 12.046 81.481 33.713 1.00 54.34 ? 115 GLU A O 1 ATOM 632 C CB . GLU A 1 91 ? 14.157 81.560 35.797 1.00 81.15 ? 115 GLU A CB 1 ATOM 633 C CG . GLU A 1 91 ? 15.368 80.731 35.416 1.00 94.95 ? 115 GLU A CG 1 ATOM 634 C CD . GLU A 1 91 ? 15.596 79.561 36.363 1.00 100.79 ? 115 GLU A CD 1 ATOM 635 O OE1 . GLU A 1 91 ? 14.824 78.579 36.296 1.00 102.60 ? 115 GLU A OE1 1 ATOM 636 O OE2 . GLU A 1 91 ? 16.544 79.623 37.174 1.00 101.45 ? 115 GLU A OE2 1 ATOM 637 N N . TYR A 1 92 ? 13.677 82.327 32.418 1.00 56.45 ? 116 TYR A N 1 ATOM 638 C CA . TYR A 1 92 ? 13.100 81.848 31.165 1.00 57.40 ? 116 TYR A CA 1 ATOM 639 C C . TYR A 1 92 ? 13.927 80.716 30.579 1.00 55.35 ? 116 TYR A C 1 ATOM 640 O O . TYR A 1 92 ? 15.146 80.699 30.738 1.00 53.03 ? 116 TYR A O 1 ATOM 641 C CB . TYR A 1 92 ? 13.035 82.978 30.125 1.00 79.94 ? 116 TYR A CB 1 ATOM 642 C CG . TYR A 1 92 ? 12.047 84.087 30.429 1.00 91.57 ? 116 TYR A CG 1 ATOM 643 C CD1 . TYR A 1 92 ? 12.353 85.092 31.346 1.00 96.35 ? 116 TYR A CD1 1 ATOM 644 C CD2 . TYR A 1 92 ? 10.804 84.132 29.795 1.00 95.87 ? 116 TYR A CD2 1 ATOM 645 C CE1 . TYR A 1 92 ? 11.451 86.113 31.623 1.00 97.93 ? 116 TYR A CE1 1 ATOM 646 C CE2 . TYR A 1 92 ? 9.896 85.149 30.066 1.00 97.16 ? 116 TYR A CE2 1 ATOM 647 C CZ . TYR A 1 92 ? 10.227 86.135 30.981 1.00 97.93 ? 116 TYR A CZ 1 ATOM 648 O OH . TYR A 1 92 ? 9.340 87.148 31.264 1.00 98.33 ? 116 TYR A OH 1 ATOM 649 N N . GLN A 1 93 ? 13.272 79.768 29.911 1.00 55.54 ? 117 GLN A N 1 ATOM 650 C CA . GLN A 1 93 ? 13.985 78.669 29.261 1.00 56.30 ? 117 GLN A CA 1 ATOM 651 C C . GLN A 1 93 ? 13.269 78.253 27.981 1.00 58.57 ? 117 GLN A C 1 ATOM 652 O O . GLN A 1 93 ? 12.072 77.967 27.979 1.00 58.79 ? 117 GLN A O 1 ATOM 653 C CB . GLN A 1 93 ? 14.161 77.469 30.200 1.00 56.36 ? 117 GLN A CB 1 ATOM 654 C CG . GLN A 1 93 ? 15.188 76.447 29.708 1.00 56.54 ? 117 GLN A CG 1 ATOM 655 C CD . GLN A 1 93 ? 15.495 75.348 30.724 1.00 58.23 ? 117 GLN A CD 1 ATOM 656 O OE1 . GLN A 1 93 ? 14.838 75.226 31.753 1.00 58.95 ? 117 GLN A OE1 1 ATOM 657 N NE2 . GLN A 1 93 ? 16.502 74.539 30.424 1.00 58.77 ? 117 GLN A NE2 1 ATOM 658 N N . CYS A 1 94 ? 14.027 78.230 26.892 1.00 70.27 ? 118 CYS A N 1 ATOM 659 C CA . CYS A 1 94 ? 13.507 77.902 25.575 1.00 73.48 ? 118 CYS A CA 1 ATOM 660 C C . CYS A 1 94 ? 13.626 76.415 25.282 1.00 73.32 ? 118 CYS A C 1 ATOM 661 O O . CYS A 1 94 ? 14.594 75.773 25.676 1.00 74.75 ? 118 CYS A O 1 ATOM 662 C CB . CYS A 1 94 ? 14.264 78.715 24.536 1.00 75.45 ? 118 CYS A CB 1 ATOM 663 S SG . CYS A 1 94 ? 13.831 78.376 22.813 1.00 77.19 ? 118 CYS A SG 1 ATOM 664 N N . PHE A 1 95 ? 12.631 75.877 24.591 1.00 68.82 ? 119 PHE A N 1 ATOM 665 C CA . PHE A 1 95 ? 12.595 74.463 24.257 1.00 66.35 ? 119 PHE A CA 1 ATOM 666 C C . PHE A 1 95 ? 12.402 74.268 22.754 1.00 68.27 ? 119 PHE A C 1 ATOM 667 O O . PHE A 1 95 ? 11.359 74.624 22.203 1.00 70.33 ? 119 PHE A O 1 ATOM 668 C CB . PHE A 1 95 ? 11.457 73.770 25.023 1.00 61.46 ? 119 PHE A CB 1 ATOM 669 C CG . PHE A 1 95 ? 11.721 73.607 26.493 1.00 56.85 ? 119 PHE A CG 1 ATOM 670 C CD1 . PHE A 1 95 ? 11.661 74.695 27.359 1.00 54.78 ? 119 PHE A CD1 1 ATOM 671 C CD2 . PHE A 1 95 ? 12.019 72.351 27.019 1.00 54.38 ? 119 PHE A CD2 1 ATOM 672 C CE1 . PHE A 1 95 ? 11.900 74.536 28.722 1.00 53.46 ? 119 PHE A CE1 1 ATOM 673 C CE2 . PHE A 1 95 ? 12.262 72.182 28.382 1.00 53.08 ? 119 PHE A CE2 1 ATOM 674 C CZ . PHE A 1 95 ? 12.198 73.276 29.233 1.00 53.46 ? 119 PHE A CZ 1 ATOM 675 N N . ALA A 1 96 ? 13.413 73.711 22.094 1.00 66.85 ? 120 ALA A N 1 ATOM 676 C CA . ALA A 1 96 ? 13.351 73.473 20.655 1.00 69.26 ? 120 ALA A CA 1 ATOM 677 C C . ALA A 1 96 ? 13.118 71.993 20.367 1.00 73.94 ? 120 ALA A C 1 ATOM 678 O O . ALA A 1 96 ? 13.976 71.151 20.633 1.00 76.40 ? 120 ALA A O 1 ATOM 679 C CB . ALA A 1 96 ? 14.629 73.957 19.985 1.00 48.93 ? 120 ALA A CB 1 ATOM 680 N N . ARG A 1 97 ? 11.946 71.689 19.818 1.00 93.41 ? 121 ARG A N 1 ATOM 681 C CA . ARG A 1 97 ? 11.562 70.317 19.537 1.00 99.69 ? 121 ARG A CA 1 ATOM 682 C C . ARG A 1 97 ? 11.255 70.040 18.070 1.00 96.77 ? 121 ARG A C 1 ATOM 683 O O . ARG A 1 97 ? 10.647 70.868 17.379 1.00 99.41 ? 121 ARG A O 1 ATOM 684 C CB . ARG A 1 97 ? 10.308 69.953 20.377 1.00 108.32 ? 121 ARG A CB 1 ATOM 685 C CG . ARG A 1 97 ? 9.621 68.644 19.994 1.00 117.13 ? 121 ARG A CG 1 ATOM 686 C CD . ARG A 1 97 ? 8.270 68.488 20.679 1.00 121.27 ? 121 ARG A CD 1 ATOM 687 N NE . ARG A 1 97 ? 7.353 67.677 19.879 1.00 122.98 ? 121 ARG A NE 1 ATOM 688 C CZ . ARG A 1 97 ? 6.151 67.265 20.284 1.00 123.81 ? 121 ARG A CZ 1 ATOM 689 N NH1 . ARG A 1 97 ? 5.699 67.579 21.496 1.00 124.08 ? 121 ARG A NH1 1 ATOM 690 N NH2 . ARG A 1 97 ? 5.393 66.537 19.469 1.00 123.78 ? 121 ARG A NH2 1 ATOM 691 N N . ASN A 1 98 ? 11.733 68.892 17.592 1.00 81.07 ? 122 ASN A N 1 ATOM 692 C CA . ASN A 1 98 ? 11.341 68.410 16.274 1.00 80.45 ? 122 ASN A CA 1 ATOM 693 C C . ASN A 1 98 ? 10.896 66.939 16.404 1.00 77.37 ? 122 ASN A C 1 ATOM 694 O O . ASN A 1 98 ? 10.731 66.429 17.527 1.00 62.50 ? 122 ASN A O 1 ATOM 695 C CB . ASN A 1 98 ? 12.417 68.607 15.192 1.00 118.63 ? 122 ASN A CB 1 ATOM 696 C CG . ASN A 1 98 ? 13.519 67.556 15.216 1.00 136.13 ? 122 ASN A CG 1 ATOM 697 O OD1 . ASN A 1 98 ? 13.507 66.617 16.014 1.00 145.20 ? 122 ASN A OD1 1 ATOM 698 N ND2 . ASN A 1 98 ? 14.490 67.717 14.314 1.00 145.00 ? 122 ASN A ND2 1 ATOM 699 N N . LYS A 1 99 ? 10.686 66.275 15.267 1.00 98.02 ? 123 LYS A N 1 ATOM 700 C CA . LYS A 1 99 ? 10.209 64.893 15.239 1.00 114.40 ? 123 LYS A CA 1 ATOM 701 C C . LYS A 1 99 ? 11.101 63.903 15.994 1.00 121.64 ? 123 LYS A C 1 ATOM 702 O O . LYS A 1 99 ? 10.603 62.930 16.576 1.00 118.86 ? 123 LYS A O 1 ATOM 703 C CB . LYS A 1 99 ? 10.002 64.441 13.777 1.00 129.76 ? 123 LYS A CB 1 ATOM 704 C CG . LYS A 1 99 ? 8.733 65.010 13.115 1.00 138.81 ? 123 LYS A CG 1 ATOM 705 C CD . LYS A 1 99 ? 7.474 64.215 13.509 1.00 143.06 ? 123 LYS A CD 1 ATOM 706 C CE . LYS A 1 99 ? 6.183 64.958 13.172 1.00 144.37 ? 123 LYS A CE 1 ATOM 707 N NZ . LYS A 1 99 ? 5.925 65.050 11.706 1.00 145.29 ? 123 LYS A NZ 1 ATOM 708 N N . PHE A 1 100 ? 12.408 64.166 16.003 1.00 124.91 ? 124 PHE A N 1 ATOM 709 C CA . PHE A 1 100 ? 13.364 63.294 16.680 1.00 126.55 ? 124 PHE A CA 1 ATOM 710 C C . PHE A 1 100 ? 13.452 63.553 18.191 1.00 128.28 ? 124 PHE A C 1 ATOM 711 O O . PHE A 1 100 ? 13.303 62.623 18.989 1.00 135.37 ? 124 PHE A O 1 ATOM 712 C CB . PHE A 1 100 ? 14.778 63.441 16.068 1.00 121.54 ? 124 PHE A CB 1 ATOM 713 C CG . PHE A 1 100 ? 14.807 63.423 14.559 1.00 118.34 ? 124 PHE A CG 1 ATOM 714 C CD1 . PHE A 1 100 ? 15.470 64.432 13.860 1.00 116.78 ? 124 PHE A CD1 1 ATOM 715 C CD2 . PHE A 1 100 ? 14.177 62.407 13.836 1.00 116.89 ? 124 PHE A CD2 1 ATOM 716 C CE1 . PHE A 1 100 ? 15.506 64.433 12.461 1.00 117.25 ? 124 PHE A CE1 1 ATOM 717 C CE2 . PHE A 1 100 ? 14.210 62.400 12.435 1.00 117.32 ? 124 PHE A CE2 1 ATOM 718 C CZ . PHE A 1 100 ? 14.875 63.415 11.749 1.00 117.08 ? 124 PHE A CZ 1 ATOM 719 N N . GLY A 1 101 ? 13.687 64.811 18.574 1.00 117.48 ? 125 GLY A N 1 ATOM 720 C CA . GLY A 1 101 ? 13.852 65.152 19.978 1.00 103.66 ? 125 GLY A CA 1 ATOM 721 C C . GLY A 1 101 ? 13.727 66.625 20.323 1.00 93.26 ? 125 GLY A C 1 ATOM 722 O O . GLY A 1 101 ? 13.202 67.411 19.531 1.00 96.53 ? 125 GLY A O 1 ATOM 723 N N . THR A 1 102 ? 14.234 66.994 21.502 1.00 81.03 ? 126 THR A N 1 ATOM 724 C CA . THR A 1 102 ? 14.117 68.359 22.026 1.00 71.13 ? 126 THR A CA 1 ATOM 725 C C . THR A 1 102 ? 15.412 68.858 22.667 1.00 66.53 ? 126 THR A C 1 ATOM 726 O O . THR A 1 102 ? 16.046 68.149 23.448 1.00 64.02 ? 126 THR A O 1 ATOM 727 C CB . THR A 1 102 ? 12.961 68.422 23.102 1.00 68.72 ? 126 THR A CB 1 ATOM 728 O OG1 . THR A 1 102 ? 11.754 67.878 22.547 1.00 67.31 ? 126 THR A OG1 1 ATOM 729 C CG2 . THR A 1 102 ? 12.699 69.857 23.558 1.00 66.37 ? 126 THR A CG2 1 ATOM 730 N N . ALA A 1 103 ? 15.799 70.080 22.314 1.00 65.99 ? 127 ALA A N 1 ATOM 731 C CA . ALA A 1 103 ? 16.997 70.723 22.851 1.00 66.26 ? 127 ALA A CA 1 ATOM 732 C C . ALA A 1 103 ? 16.587 71.948 23.667 1.00 65.93 ? 127 ALA A C 1 ATOM 733 O O . ALA A 1 103 ? 15.638 72.645 23.308 1.00 67.07 ? 127 ALA A O 1 ATOM 734 C CB . ALA A 1 103 ? 17.930 71.135 21.729 1.00 62.26 ? 127 ALA A CB 1 ATOM 735 N N . LEU A 1 104 ? 17.319 72.216 24.752 1.00 63.20 ? 128 LEU A N 1 ATOM 736 C CA . LEU A 1 104 ? 16.974 73.325 25.640 1.00 60.48 ? 128 LEU A CA 1 ATOM 737 C C . LEU A 1 104 ? 18.012 74.425 25.632 1.00 59.99 ? 128 LEU A C 1 ATOM 738 O O . LEU A 1 104 ? 19.184 74.185 25.372 1.00 60.83 ? 128 LEU A O 1 ATOM 739 C CB . LEU A 1 104 ? 16.807 72.828 27.098 1.00 55.06 ? 128 LEU A CB 1 ATOM 740 C CG . LEU A 1 104 ? 16.463 71.362 27.432 1.00 55.75 ? 128 LEU A CG 1 ATOM 741 C CD1 . LEU A 1 104 ? 16.404 71.183 28.940 1.00 53.42 ? 128 LEU A CD1 1 ATOM 742 C CD2 . LEU A 1 104 ? 15.145 70.915 26.794 1.00 55.13 ? 128 LEU A CD2 1 ATOM 743 N N . SER A 1 105 ? 17.565 75.642 25.901 1.00 57.90 ? 129 SER A N 1 ATOM 744 C CA . SER A 1 105 ? 18.462 76.776 26.013 1.00 57.81 ? 129 SER A CA 1 ATOM 745 C C . SER A 1 105 ? 18.838 76.896 27.486 1.00 56.17 ? 129 SER A C 1 ATOM 746 O O . SER A 1 105 ? 18.348 76.140 28.327 1.00 54.88 ? 129 SER A O 1 ATOM 747 C CB . SER A 1 105 ? 17.759 78.064 25.598 1.00 65.19 ? 129 SER A CB 1 ATOM 748 O OG . SER A 1 105 ? 16.837 78.488 26.591 1.00 67.58 ? 129 SER A OG 1 ATOM 749 N N . ASN A 1 106 ? 19.725 77.841 27.779 1.00 55.22 ? 130 ASN A N 1 ATOM 750 C CA . ASN A 1 106 ? 20.106 78.122 29.146 1.00 54.99 ? 130 ASN A CA 1 ATOM 751 C C . ASN A 1 106 ? 18.899 78.728 29.882 1.00 54.30 ? 130 ASN A C 1 ATOM 752 O O . ASN A 1 106 ? 17.857 79.006 29.275 1.00 52.54 ? 130 ASN A O 1 ATOM 753 C CB . ASN A 1 106 ? 21.269 79.123 29.176 1.00 62.30 ? 130 ASN A CB 1 ATOM 754 C CG . ASN A 1 106 ? 22.588 78.510 28.691 1.00 66.22 ? 130 ASN A CG 1 ATOM 755 O OD1 . ASN A 1 106 ? 22.969 77.410 29.107 1.00 67.03 ? 130 ASN A OD1 1 ATOM 756 N ND2 . ASN A 1 106 ? 23.295 79.231 27.826 1.00 65.49 ? 130 ASN A ND2 1 ATOM 757 N N . ARG A 1 107 ? 19.035 78.896 31.196 1.00 57.10 ? 131 ARG A N 1 ATOM 758 C CA . ARG A 1 107 ? 17.995 79.523 32.005 1.00 59.34 ? 131 ARG A CA 1 ATOM 759 C C . ARG A 1 107 ? 18.253 81.023 32.040 1.00 57.58 ? 131 ARG A C 1 ATOM 760 O O . ARG A 1 107 ? 19.075 81.511 32.816 1.00 60.20 ? 131 ARG A O 1 ATOM 761 C CB . ARG A 1 107 ? 17.964 78.923 33.414 1.00 71.44 ? 131 ARG A CB 1 ATOM 762 C CG . ARG A 1 107 ? 17.160 77.629 33.467 1.00 75.56 ? 131 ARG A CG 1 ATOM 763 C CD . ARG A 1 107 ? 17.301 76.881 34.776 1.00 77.01 ? 131 ARG A CD 1 ATOM 764 N NE . ARG A 1 107 ? 16.641 75.578 34.695 1.00 76.13 ? 131 ARG A NE 1 ATOM 765 C CZ . ARG A 1 107 ? 16.552 74.705 35.700 1.00 76.66 ? 131 ARG A CZ 1 ATOM 766 N NH1 . ARG A 1 107 ? 17.081 74.983 36.891 1.00 75.77 ? 131 ARG A NH1 1 ATOM 767 N NH2 . ARG A 1 107 ? 15.926 73.545 35.513 1.00 76.63 ? 131 ARG A NH2 1 ATOM 768 N N . ILE A 1 108 ? 17.528 81.736 31.179 1.00 55.14 ? 132 ILE A N 1 ATOM 769 C CA . ILE A 1 108 ? 17.670 83.177 31.022 1.00 53.96 ? 132 ILE A CA 1 ATOM 770 C C . ILE A 1 108 ? 17.016 83.949 32.164 1.00 56.72 ? 132 ILE A C 1 ATOM 771 O O . ILE A 1 108 ? 15.793 84.043 32.231 1.00 52.51 ? 132 ILE A O 1 ATOM 772 C CB . ILE A 1 108 ? 17.028 83.672 29.673 1.00 54.18 ? 132 ILE A CB 1 ATOM 773 C CG1 . ILE A 1 108 ? 17.258 82.668 28.529 1.00 55.19 ? 132 ILE A CG1 1 ATOM 774 C CG2 . ILE A 1 108 ? 17.537 85.057 29.318 1.00 53.63 ? 132 ILE A CG2 1 ATOM 775 C CD1 . ILE A 1 108 ? 18.715 82.364 28.155 1.00 64.64 ? 132 ILE A CD1 1 ATOM 776 N N . ARG A 1 109 ? 17.834 84.475 33.073 1.00 71.11 ? 133 ARG A N 1 ATOM 777 C CA . ARG A 1 109 ? 17.327 85.303 34.165 1.00 83.46 ? 133 ARG A CA 1 ATOM 778 C C . ARG A 1 109 ? 17.250 86.759 33.677 1.00 88.02 ? 133 ARG A C 1 ATOM 779 O O . ARG A 1 109 ? 18.242 87.493 33.689 1.00 84.89 ? 133 ARG A O 1 ATOM 780 C CB . ARG A 1 109 ? 18.224 85.209 35.404 1.00 113.54 ? 133 ARG A CB 1 ATOM 781 C CG . ARG A 1 109 ? 18.143 83.868 36.141 1.00 130.09 ? 133 ARG A CG 1 ATOM 782 C CD . ARG A 1 109 ? 16.910 83.782 37.046 1.00 138.02 ? 133 ARG A CD 1 ATOM 783 N NE . ARG A 1 109 ? 16.862 82.548 37.835 1.00 140.96 ? 133 ARG A NE 1 ATOM 784 C CZ . ARG A 1 109 ? 17.429 82.383 39.032 1.00 142.50 ? 133 ARG A CZ 1 ATOM 785 N NH1 . ARG A 1 109 ? 18.102 83.378 39.605 1.00 142.56 ? 133 ARG A NH1 1 ATOM 786 N NH2 . ARG A 1 109 ? 17.320 81.218 39.667 1.00 143.33 ? 133 ARG A NH2 1 ATOM 787 N N . LEU A 1 110 ? 16.057 87.153 33.227 1.00 100.25 ? 134 LEU A N 1 ATOM 788 C CA . LEU A 1 110 ? 15.808 88.509 32.739 1.00 104.60 ? 134 LEU A CA 1 ATOM 789 C C . LEU A 1 110 ? 15.556 89.438 33.922 1.00 101.71 ? 134 LEU A C 1 ATOM 790 O O . LEU A 1 110 ? 14.714 89.157 34.784 1.00 108.18 ? 134 LEU A O 1 ATOM 791 C CB . LEU A 1 110 ? 14.609 88.525 31.781 1.00 98.95 ? 134 LEU A CB 1 ATOM 792 C CG . LEU A 1 110 ? 14.189 89.891 31.217 1.00 99.60 ? 134 LEU A CG 1 ATOM 793 C CD1 . LEU A 1 110 ? 14.971 90.223 29.945 1.00 99.03 ? 134 LEU A CD1 1 ATOM 794 C CD2 . LEU A 1 110 ? 12.695 89.885 30.937 1.00 98.85 ? 134 LEU A CD2 1 ATOM 795 N N . GLN A 1 111 ? 16.293 90.547 33.943 1.00 87.34 ? 135 GLN A N 1 ATOM 796 C CA . GLN A 1 111 ? 16.209 91.513 35.037 1.00 82.11 ? 135 GLN A CA 1 ATOM 797 C C . GLN A 1 111 ? 16.241 92.947 34.498 1.00 80.06 ? 135 GLN A C 1 ATOM 798 O O . GLN A 1 111 ? 16.908 93.223 33.493 1.00 72.66 ? 135 GLN A O 1 ATOM 799 C CB . GLN A 1 111 ? 17.373 91.266 36.008 1.00 81.54 ? 135 GLN A CB 1 ATOM 800 C CG . GLN A 1 111 ? 17.042 91.504 37.480 1.00 83.58 ? 135 GLN A CG 1 ATOM 801 C CD . GLN A 1 111 ? 18.118 90.960 38.420 1.00 85.33 ? 135 GLN A CD 1 ATOM 802 O OE1 . GLN A 1 111 ? 19.240 90.656 38.001 1.00 85.18 ? 135 GLN A OE1 1 ATOM 803 N NE2 . GLN A 1 111 ? 17.778 90.840 39.699 1.00 85.38 ? 135 GLN A NE2 1 ATOM 804 N N . VAL A 1 112 ? 15.513 93.851 35.159 1.00 92.09 ? 136 VAL A N 1 ATOM 805 C CA . VAL A 1 112 ? 15.459 95.244 34.721 1.00 97.56 ? 136 VAL A CA 1 ATOM 806 C C . VAL A 1 112 ? 16.621 96.088 35.236 1.00 101.88 ? 136 VAL A C 1 ATOM 807 O O . VAL A 1 112 ? 16.948 96.052 36.425 1.00 108.00 ? 136 VAL A O 1 ATOM 808 C CB . VAL A 1 112 ? 14.107 95.955 35.122 1.00 98.25 ? 136 VAL A CB 1 ATOM 809 C CG1 . VAL A 1 112 ? 12.938 95.293 34.407 1.00 94.71 ? 136 VAL A CG1 1 ATOM 810 C CG2 . VAL A 1 112 ? 13.905 95.958 36.640 1.00 94.22 ? 136 VAL A CG2 1 ATOM 811 N N . SER A 1 113 ? 17.251 96.828 34.320 1.00 93.81 ? 137 SER A N 1 ATOM 812 C CA . SER A 1 113 ? 18.356 97.730 34.659 1.00 89.54 ? 137 SER A CA 1 ATOM 813 C C . SER A 1 113 ? 17.842 98.901 35.492 1.00 84.37 ? 137 SER A C 1 ATOM 814 O O . SER A 1 113 ? 17.365 99.905 34.962 1.00 79.15 ? 137 SER A O 1 ATOM 815 C CB . SER A 1 113 ? 19.036 98.263 33.390 1.00 105.55 ? 137 SER A CB 1 ATOM 816 O OG . SER A 1 113 ? 20.023 97.363 32.922 1.00 112.51 ? 137 SER A OG 1 ATOM 817 N N . LYS A 1 114 ? 17.940 98.759 36.804 1.00 85.77 ? 138 LYS A N 1 ATOM 818 C CA . LYS A 1 114 ? 17.487 99.800 37.693 1.00 91.77 ? 138 LYS A CA 1 ATOM 819 C C . LYS A 1 114 ? 18.535 100.891 37.932 1.00 92.61 ? 138 LYS A C 1 ATOM 820 O O . LYS A 1 114 ? 19.734 100.613 38.042 1.00 87.00 ? 138 LYS A O 1 ATOM 821 C CB . LYS A 1 114 ? 17.072 99.188 39.048 1.00 114.75 ? 138 LYS A CB 1 ATOM 822 C CG . LYS A 1 114 ? 15.586 98.828 39.148 1.00 124.68 ? 138 LYS A CG 1 ATOM 823 C CD . LYS A 1 114 ? 14.761 99.981 39.729 1.00 129.09 ? 138 LYS A CD 1 ATOM 824 C CE . LYS A 1 114 ? 13.303 99.582 39.956 1.00 130.36 ? 138 LYS A CE 1 ATOM 825 N NZ . LYS A 1 114 ? 13.132 98.597 41.064 1.00 130.89 ? 138 LYS A NZ 1 ATOM 826 N N . SER A 1 115 ? 18.075 102.140 37.956 1.00 106.55 ? 139 SER A N 1 ATOM 827 C CA . SER A 1 115 ? 18.921 103.287 38.342 1.00 110.97 ? 139 SER A CA 1 ATOM 828 C C . SER A 1 115 ? 18.045 104.038 39.364 1.00 115.14 ? 139 SER A C 1 ATOM 829 O O . SER A 1 115 ? 17.613 105.172 39.127 1.00 118.34 ? 139 SER A O 1 ATOM 830 C CB . SER A 1 115 ? 19.254 104.157 37.135 1.00 91.53 ? 139 SER A CB 1 ATOM 831 O OG . SER A 1 115 ? 18.109 104.487 36.373 1.00 85.42 ? 139 SER A OG 1 ATOM 832 N N . PRO A 1 116 ? 17.846 103.429 40.553 1.00 100.55 ? 140 PRO A N 1 ATOM 833 C CA . PRO A 1 116 ? 17.002 104.003 41.602 1.00 96.28 ? 140 PRO A CA 1 ATOM 834 C C . PRO A 1 116 ? 17.507 105.203 42.352 1.00 88.90 ? 140 PRO A C 1 ATOM 835 O O . PRO A 1 116 ? 18.705 105.453 42.375 1.00 78.68 ? 140 PRO A O 1 ATOM 836 C CB . PRO A 1 116 ? 16.732 102.805 42.527 1.00 109.23 ? 140 PRO A CB 1 ATOM 837 C CG . PRO A 1 116 ? 17.591 101.658 41.979 1.00 116.65 ? 140 PRO A CG 1 ATOM 838 C CD . PRO A 1 116 ? 18.616 102.300 41.106 1.00 112.00 ? 140 PRO A CD 1 ATOM 839 N N . LEU A 1 117 ? 16.584 105.925 42.985 1.00 92.65 ? 141 LEU A N 1 ATOM 840 C CA . LEU A 1 117 ? 16.916 107.129 43.735 1.00 93.87 ? 141 LEU A CA 1 ATOM 841 C C . LEU A 1 117 ? 17.446 106.859 45.131 1.00 91.49 ? 141 LEU A C 1 ATOM 842 O O . LEU A 1 117 ? 17.271 105.772 45.685 1.00 94.05 ? 141 LEU A O 1 ATOM 843 C CB . LEU A 1 117 ? 15.674 108.023 43.849 1.00 102.35 ? 141 LEU A CB 1 ATOM 844 C CG . LEU A 1 117 ? 15.368 108.926 42.650 1.00 105.18 ? 141 LEU A CG 1 ATOM 845 C CD1 . LEU A 1 117 ? 13.881 109.255 42.595 1.00 105.84 ? 141 LEU A CD1 1 ATOM 846 C CD2 . LEU A 1 117 ? 16.215 110.188 42.734 1.00 106.34 ? 141 LEU A CD2 1 ATOM 847 N N . TRP A 1 118 ? 18.104 107.861 45.689 1.00 83.12 ? 142 TRP A N 1 ATOM 848 C CA . TRP A 1 118 ? 18.599 107.771 47.047 1.00 84.48 ? 142 TRP A CA 1 ATOM 849 C C . TRP A 1 118 ? 17.474 108.024 48.045 1.00 92.03 ? 142 TRP A C 1 ATOM 850 O O . TRP A 1 118 ? 16.576 108.839 47.788 1.00 85.36 ? 142 TRP A O 1 ATOM 851 C CB . TRP A 1 118 ? 19.671 108.830 47.300 1.00 86.05 ? 142 TRP A CB 1 ATOM 852 C CG . TRP A 1 118 ? 20.983 108.521 46.672 1.00 85.11 ? 142 TRP A CG 1 ATOM 853 C CD1 . TRP A 1 118 ? 21.310 108.619 45.348 1.00 85.97 ? 142 TRP A CD1 1 ATOM 854 C CD2 . TRP A 1 118 ? 22.156 108.056 47.339 1.00 84.54 ? 142 TRP A CD2 1 ATOM 855 N NE1 . TRP A 1 118 ? 22.622 108.246 45.151 1.00 85.14 ? 142 TRP A NE1 1 ATOM 856 C CE2 . TRP A 1 118 ? 23.164 107.895 46.357 1.00 84.59 ? 142 TRP A CE2 1 ATOM 857 C CE3 . TRP A 1 118 ? 22.456 107.759 48.673 1.00 84.34 ? 142 TRP A CE3 1 ATOM 858 C CZ2 . TRP A 1 118 ? 24.444 107.452 46.666 1.00 83.94 ? 142 TRP A CZ2 1 ATOM 859 C CZ3 . TRP A 1 118 ? 23.727 107.319 48.982 1.00 84.77 ? 142 TRP A CZ3 1 ATOM 860 C CH2 . TRP A 1 118 ? 24.708 107.169 47.982 1.00 85.33 ? 142 TRP A CH2 1 ATOM 861 N N . PRO A 1 119 ? 17.487 107.291 49.178 1.00 110.03 ? 143 PRO A N 1 ATOM 862 C CA . PRO A 1 119 ? 16.470 107.474 50.220 1.00 119.85 ? 143 PRO A CA 1 ATOM 863 C C . PRO A 1 119 ? 16.590 108.921 50.738 1.00 124.92 ? 143 PRO A C 1 ATOM 864 O O . PRO A 1 119 ? 17.704 109.440 50.920 1.00 130.43 ? 143 PRO A O 1 ATOM 865 C CB . PRO A 1 119 ? 16.896 106.494 51.306 1.00 125.52 ? 143 PRO A CB 1 ATOM 866 C CG . PRO A 1 119 ? 17.591 105.402 50.564 1.00 123.72 ? 143 PRO A CG 1 ATOM 867 C CD . PRO A 1 119 ? 18.330 106.107 49.454 1.00 119.79 ? 143 PRO A CD 1 ATOM 868 N N . LYS A 1 120 ? 15.441 109.555 50.964 1.00 129.78 ? 144 LYS A N 1 ATOM 869 C CA . LYS A 1 120 ? 15.382 110.928 51.463 1.00 125.27 ? 144 LYS A CA 1 ATOM 870 C C . LYS A 1 120 ? 16.024 111.033 52.842 1.00 121.79 ? 144 LYS A C 1 ATOM 871 O O . LYS A 1 120 ? 15.617 110.350 53.787 1.00 119.58 ? 144 LYS A O 1 ATOM 872 C CB . LYS A 1 120 ? 13.924 111.434 51.492 1.00 135.51 ? 144 LYS A CB 1 ATOM 873 C CG . LYS A 1 120 ? 12.834 110.345 51.496 1.00 144.52 ? 144 LYS A CG 1 ATOM 874 C CD . LYS A 1 120 ? 12.576 109.743 52.878 1.00 149.14 ? 144 LYS A CD 1 ATOM 875 C CE . LYS A 1 120 ? 11.600 108.572 52.799 1.00 150.64 ? 144 LYS A CE 1 ATOM 876 N NZ . LYS A 1 120 ? 11.258 108.021 54.142 1.00 151.15 ? 144 LYS A NZ 1 ATOM 877 N N . GLU A 1 121 ? 17.044 111.880 52.948 1.00 118.75 ? 145 GLU A N 1 ATOM 878 C CA . GLU A 1 121 ? 17.755 112.038 54.208 1.00 121.19 ? 145 GLU A CA 1 ATOM 879 C C . GLU A 1 121 ? 18.305 113.439 54.442 1.00 120.53 ? 145 GLU A C 1 ATOM 880 O O . GLU A 1 121 ? 18.934 114.036 53.562 1.00 118.50 ? 145 GLU A O 1 ATOM 881 C CB . GLU A 1 121 ? 18.904 111.001 54.308 1.00 133.47 ? 145 GLU A CB 1 ATOM 882 C CG . GLU A 1 121 ? 19.827 110.909 53.081 1.00 139.30 ? 145 GLU A CG 1 ATOM 883 C CD . GLU A 1 121 ? 20.815 109.750 53.157 1.00 141.35 ? 145 GLU A CD 1 ATOM 884 O OE1 . GLU A 1 121 ? 20.381 108.605 53.404 1.00 142.16 ? 145 GLU A OE1 1 ATOM 885 O OE2 . GLU A 1 121 ? 22.026 109.984 52.960 1.00 141.47 ? 145 GLU A OE2 1 ATOM 886 N N . ASN A 1 122 ? 18.022 113.970 55.631 1.00 135.60 ? 146 ASN A N 1 ATOM 887 C CA . ASN A 1 122 ? 18.548 115.272 56.041 1.00 137.31 ? 146 ASN A CA 1 ATOM 888 C C . ASN A 1 122 ? 19.879 115.002 56.765 1.00 135.29 ? 146 ASN A C 1 ATOM 889 O O . ASN A 1 122 ? 19.911 114.610 57.937 1.00 146.75 ? 146 ASN A O 1 ATOM 890 C CB . ASN A 1 122 ? 17.557 115.995 56.956 1.00 119.72 ? 146 ASN A CB 1 ATOM 891 C CG . ASN A 1 122 ? 17.856 117.487 57.069 1.00 112.91 ? 146 ASN A CG 1 ATOM 892 O OD1 . ASN A 1 122 ? 18.754 118.010 56.402 1.00 109.38 ? 146 ASN A OD1 1 ATOM 893 N ND2 . ASN A 1 122 ? 17.097 118.177 57.910 1.00 108.79 ? 146 ASN A ND2 1 ATOM 894 N N . LEU A 1 123 ? 20.976 115.223 56.042 1.00 106.96 ? 147 LEU A N 1 ATOM 895 C CA . LEU A 1 123 ? 22.308 114.928 56.553 1.00 103.42 ? 147 LEU A CA 1 ATOM 896 C C . LEU A 1 123 ? 22.812 115.875 57.622 1.00 107.58 ? 147 LEU A C 1 ATOM 897 O O . LEU A 1 123 ? 22.496 117.064 57.619 1.00 99.87 ? 147 LEU A O 1 ATOM 898 C CB . LEU A 1 123 ? 23.328 114.878 55.390 1.00 87.70 ? 147 LEU A CB 1 ATOM 899 C CG . LEU A 1 123 ? 23.290 113.665 54.439 1.00 80.24 ? 147 LEU A CG 1 ATOM 900 C CD1 . LEU A 1 123 ? 24.227 113.896 53.273 1.00 75.49 ? 147 LEU A CD1 1 ATOM 901 C CD2 . LEU A 1 123 ? 23.658 112.374 55.172 1.00 75.84 ? 147 LEU A CD2 1 ATOM 902 N N . ASP A 1 124 ? 23.583 115.325 58.551 1.00 142.58 ? 148 ASP A N 1 ATOM 903 C CA . ASP A 1 124 ? 24.203 116.116 59.596 1.00 151.66 ? 148 ASP A CA 1 ATOM 904 C C . ASP A 1 124 ? 25.417 116.872 59.054 1.00 148.56 ? 148 ASP A C 1 ATOM 905 O O . ASP A 1 124 ? 26.170 116.341 58.227 1.00 157.53 ? 148 ASP A O 1 ATOM 906 C CB . ASP A 1 124 ? 24.713 115.208 60.735 1.00 139.82 ? 148 ASP A CB 1 ATOM 907 C CG . ASP A 1 124 ? 23.597 114.677 61.623 1.00 141.53 ? 148 ASP A CG 1 ATOM 908 O OD1 . ASP A 1 124 ? 23.780 113.599 62.234 1.00 141.87 ? 148 ASP A OD1 1 ATOM 909 O OD2 . ASP A 1 124 ? 22.541 115.340 61.723 1.00 142.15 ? 148 ASP A OD2 1 ATOM 910 N N . PRO A 1 125 ? 25.576 118.149 59.457 1.00 115.06 ? 149 PRO A N 1 ATOM 911 C CA . PRO A 1 125 ? 26.740 118.933 59.019 1.00 106.14 ? 149 PRO A CA 1 ATOM 912 C C . PRO A 1 125 ? 27.954 118.220 59.654 1.00 101.15 ? 149 PRO A C 1 ATOM 913 O O . PRO A 1 125 ? 27.929 117.863 60.842 1.00 108.25 ? 149 PRO A O 1 ATOM 914 C CB . PRO A 1 125 ? 26.511 120.303 59.644 1.00 93.24 ? 149 PRO A CB 1 ATOM 915 C CG . PRO A 1 125 ? 25.481 120.081 60.713 1.00 90.01 ? 149 PRO A CG 1 ATOM 916 C CD . PRO A 1 125 ? 24.607 118.991 60.179 1.00 98.35 ? 149 PRO A CD 1 ATOM 917 N N . VAL A 1 126 ? 29.011 118.025 58.874 1.00 106.59 ? 150 VAL A N 1 ATOM 918 C CA . VAL A 1 126 ? 30.156 117.278 59.367 1.00 102.75 ? 150 VAL A CA 1 ATOM 919 C C . VAL A 1 126 ? 31.201 118.143 60.034 1.00 99.96 ? 150 VAL A C 1 ATOM 920 O O . VAL A 1 126 ? 31.779 119.038 59.415 1.00 95.41 ? 150 VAL A O 1 ATOM 921 C CB . VAL A 1 126 ? 30.800 116.427 58.228 1.00 104.84 ? 150 VAL A CB 1 ATOM 922 C CG1 . VAL A 1 126 ? 31.987 115.643 58.769 1.00 106.27 ? 150 VAL A CG1 1 ATOM 923 C CG2 . VAL A 1 126 ? 29.767 115.466 57.641 1.00 106.37 ? 150 VAL A CG2 1 ATOM 924 N N . VAL A 1 127 ? 31.411 117.878 61.321 1.00 111.36 ? 151 VAL A N 1 ATOM 925 C CA . VAL A 1 127 ? 32.397 118.602 62.110 1.00 118.94 ? 151 VAL A CA 1 ATOM 926 C C . VAL A 1 127 ? 33.478 117.626 62.581 1.00 123.78 ? 151 VAL A C 1 ATOM 927 O O . VAL A 1 127 ? 33.190 116.638 63.266 1.00 132.10 ? 151 VAL A O 1 ATOM 928 C CB . VAL A 1 127 ? 31.753 119.296 63.349 1.00 106.08 ? 151 VAL A CB 1 ATOM 929 C CG1 . VAL A 1 127 ? 32.789 120.152 64.070 1.00 99.00 ? 151 VAL A CG1 1 ATOM 930 C CG2 . VAL A 1 127 ? 30.568 120.156 62.922 1.00 98.85 ? 151 VAL A CG2 1 ATOM 931 N N . VAL A 1 128 ? 34.720 117.904 62.188 1.00 113.45 ? 152 VAL A N 1 ATOM 932 C CA . VAL A 1 128 ? 35.855 117.077 62.572 1.00 116.12 ? 152 VAL A CA 1 ATOM 933 C C . VAL A 1 128 ? 37.068 117.941 62.925 1.00 114.86 ? 152 VAL A C 1 ATOM 934 O O . VAL A 1 128 ? 37.286 119.000 62.321 1.00 113.94 ? 152 VAL A O 1 ATOM 935 C CB . VAL A 1 128 ? 36.221 116.056 61.431 1.00 107.55 ? 152 VAL A CB 1 ATOM 936 C CG1 . VAL A 1 128 ? 36.752 116.778 60.190 1.00 104.46 ? 152 VAL A CG1 1 ATOM 937 C CG2 . VAL A 1 128 ? 37.226 115.026 61.941 1.00 104.99 ? 152 VAL A CG2 1 ATOM 938 N N . GLN A 1 129 ? 37.832 117.501 63.926 1.00 123.68 ? 153 GLN A N 1 ATOM 939 C CA . GLN A 1 129 ? 39.045 118.209 64.338 1.00 124.46 ? 153 GLN A CA 1 ATOM 940 C C . GLN A 1 129 ? 40.093 118.153 63.220 1.00 118.42 ? 153 GLN A C 1 ATOM 941 O O . GLN A 1 129 ? 40.223 117.144 62.525 1.00 121.79 ? 153 GLN A O 1 ATOM 942 C CB . GLN A 1 129 ? 39.612 117.601 65.628 1.00 126.45 ? 153 GLN A CB 1 ATOM 943 C CG . GLN A 1 129 ? 38.806 117.941 66.875 1.00 131.20 ? 153 GLN A CG 1 ATOM 944 C CD . GLN A 1 129 ? 39.346 117.271 68.130 1.00 133.24 ? 153 GLN A CD 1 ATOM 945 O OE1 . GLN A 1 129 ? 40.559 117.235 68.363 1.00 133.65 ? 153 GLN A OE1 1 ATOM 946 N NE2 . GLN A 1 129 ? 38.443 116.749 68.956 1.00 133.85 ? 153 GLN A NE2 1 ATOM 947 N N . GLU A 1 130 ? 40.821 119.253 63.044 1.00 113.86 ? 154 GLU A N 1 ATOM 948 C CA . GLU A 1 130 ? 41.848 119.352 62.011 1.00 110.26 ? 154 GLU A CA 1 ATOM 949 C C . GLU A 1 130 ? 42.938 118.322 62.261 1.00 109.91 ? 154 GLU A C 1 ATOM 950 O O . GLU A 1 130 ? 43.300 118.067 63.411 1.00 99.82 ? 154 GLU A O 1 ATOM 951 C CB . GLU A 1 130 ? 42.445 120.758 61.997 1.00 102.79 ? 154 GLU A CB 1 ATOM 952 C CG . GLU A 1 130 ? 43.352 121.041 60.813 1.00 108.66 ? 154 GLU A CG 1 ATOM 953 C CD . GLU A 1 130 ? 44.103 122.352 60.955 1.00 111.86 ? 154 GLU A CD 1 ATOM 954 O OE1 . GLU A 1 130 ? 43.858 123.086 61.941 1.00 112.22 ? 154 GLU A OE1 1 ATOM 955 O OE2 . GLU A 1 130 ? 44.939 122.648 60.076 1.00 113.02 ? 154 GLU A OE2 1 ATOM 956 N N . GLY A 1 131 ? 43.443 117.729 61.177 1.00 104.46 ? 155 GLY A N 1 ATOM 957 C CA . GLY A 1 131 ? 44.475 116.703 61.264 1.00 115.67 ? 155 GLY A CA 1 ATOM 958 C C . GLY A 1 131 ? 43.932 115.307 61.555 1.00 118.53 ? 155 GLY A C 1 ATOM 959 O O . GLY A 1 131 ? 44.584 114.303 61.248 1.00 122.06 ? 155 GLY A O 1 ATOM 960 N N . ALA A 1 132 ? 42.746 115.250 62.163 1.00 110.75 ? 156 ALA A N 1 ATOM 961 C CA . ALA A 1 132 ? 42.088 113.984 62.486 1.00 107.65 ? 156 ALA A CA 1 ATOM 962 C C . ALA A 1 132 ? 41.518 113.329 61.216 1.00 109.21 ? 156 ALA A C 1 ATOM 963 O O . ALA A 1 132 ? 41.320 113.995 60.198 1.00 107.47 ? 156 ALA A O 1 ATOM 964 C CB . ALA A 1 132 ? 40.982 114.216 63.523 1.00 109.13 ? 156 ALA A CB 1 ATOM 965 N N . PRO A 1 133 ? 41.263 112.008 61.260 1.00 107.05 ? 157 PRO A N 1 ATOM 966 C CA . PRO A 1 133 ? 40.724 111.293 60.099 1.00 104.33 ? 157 PRO A CA 1 ATOM 967 C C . PRO A 1 133 ? 39.207 111.362 59.961 1.00 96.67 ? 157 PRO A C 1 ATOM 968 O O . PRO A 1 133 ? 38.507 111.604 60.941 1.00 90.48 ? 157 PRO A O 1 ATOM 969 C CB . PRO A 1 133 ? 41.189 109.860 60.331 1.00 128.70 ? 157 PRO A CB 1 ATOM 970 C CG . PRO A 1 133 ? 41.204 109.726 61.820 1.00 135.47 ? 157 PRO A CG 1 ATOM 971 C CD . PRO A 1 133 ? 41.566 111.084 62.373 1.00 130.71 ? 157 PRO A CD 1 ATOM 972 N N . LEU A 1 134 ? 38.712 111.132 58.743 1.00 95.69 ? 158 LEU A N 1 ATOM 973 C CA . LEU A 1 134 ? 37.274 111.118 58.464 1.00 91.58 ? 158 LEU A CA 1 ATOM 974 C C . LEU A 1 134 ? 36.927 110.276 57.233 1.00 89.59 ? 158 LEU A C 1 ATOM 975 O O . LEU A 1 134 ? 37.660 110.262 56.238 1.00 86.81 ? 158 LEU A O 1 ATOM 976 C CB . LEU A 1 134 ? 36.745 112.545 58.255 1.00 106.06 ? 158 LEU A CB 1 ATOM 977 C CG . LEU A 1 134 ? 35.243 112.742 57.976 1.00 106.26 ? 158 LEU A CG 1 ATOM 978 C CD1 . LEU A 1 134 ? 34.406 112.487 59.222 1.00 106.56 ? 158 LEU A CD1 1 ATOM 979 C CD2 . LEU A 1 134 ? 35.009 114.153 57.466 1.00 106.99 ? 158 LEU A CD2 1 ATOM 980 N N . THR A 1 135 ? 35.803 109.570 57.321 1.00 86.12 ? 159 THR A N 1 ATOM 981 C CA . THR A 1 135 ? 35.312 108.767 56.218 1.00 81.74 ? 159 THR A CA 1 ATOM 982 C C . THR A 1 135 ? 33.901 109.196 55.821 1.00 82.42 ? 159 THR A C 1 ATOM 983 O O . THR A 1 135 ? 32.946 109.005 56.579 1.00 85.79 ? 159 THR A O 1 ATOM 984 C CB . THR A 1 135 ? 35.284 107.260 56.574 1.00 76.01 ? 159 THR A CB 1 ATOM 985 O OG1 . THR A 1 135 ? 36.594 106.846 56.979 1.00 71.16 ? 159 THR A OG1 1 ATOM 986 C CG2 . THR A 1 135 ? 34.844 106.427 55.375 1.00 69.34 ? 159 THR A CG2 1 ATOM 987 N N . LEU A 1 136 ? 33.782 109.809 54.646 1.00 79.86 ? 160 LEU A N 1 ATOM 988 C CA . LEU A 1 136 ? 32.468 110.171 54.124 1.00 76.40 ? 160 LEU A CA 1 ATOM 989 C C . LEU A 1 136 ? 31.925 108.944 53.398 1.00 76.54 ? 160 LEU A C 1 ATOM 990 O O . LEU A 1 136 ? 32.261 108.678 52.239 1.00 76.14 ? 160 LEU A O 1 ATOM 991 C CB . LEU A 1 136 ? 32.542 111.364 53.159 1.00 71.69 ? 160 LEU A CB 1 ATOM 992 C CG . LEU A 1 136 ? 32.821 112.748 53.765 1.00 69.90 ? 160 LEU A CG 1 ATOM 993 C CD1 . LEU A 1 136 ? 32.942 113.770 52.651 1.00 70.45 ? 160 LEU A CD1 1 ATOM 994 C CD2 . LEU A 1 136 ? 31.732 113.149 54.744 1.00 69.13 ? 160 LEU A CD2 1 ATOM 995 N N . GLN A 1 137 ? 31.094 108.189 54.108 1.00 76.40 ? 161 GLN A N 1 ATOM 996 C CA . GLN A 1 137 ? 30.497 106.980 53.560 1.00 81.11 ? 161 GLN A CA 1 ATOM 997 C C . GLN A 1 137 ? 29.423 107.309 52.532 1.00 79.92 ? 161 GLN A C 1 ATOM 998 O O . GLN A 1 137 ? 28.524 108.112 52.790 1.00 78.46 ? 161 GLN A O 1 ATOM 999 C CB . GLN A 1 137 ? 29.930 106.108 54.692 1.00 99.39 ? 161 GLN A CB 1 ATOM 1000 C CG . GLN A 1 137 ? 29.197 106.877 55.779 1.00 106.59 ? 161 GLN A CG 1 ATOM 1001 C CD . GLN A 1 137 ? 29.494 106.345 57.171 1.00 109.58 ? 161 GLN A CD 1 ATOM 1002 O OE1 . GLN A 1 137 ? 29.526 105.134 57.395 1.00 109.50 ? 161 GLN A OE1 1 ATOM 1003 N NE2 . GLN A 1 137 ? 29.708 107.255 58.115 1.00 110.12 ? 161 GLN A NE2 1 ATOM 1004 N N . CYS A 1 138 ? 29.541 106.699 51.355 1.00 80.67 ? 162 CYS A N 1 ATOM 1005 C CA . CYS A 1 138 ? 28.588 106.924 50.283 1.00 81.12 ? 162 CYS A CA 1 ATOM 1006 C C . CYS A 1 138 ? 27.352 106.046 50.473 1.00 82.79 ? 162 CYS A C 1 ATOM 1007 O O . CYS A 1 138 ? 26.250 106.562 50.657 1.00 81.89 ? 162 CYS A O 1 ATOM 1008 C CB . CYS A 1 138 ? 29.238 106.646 48.915 1.00 85.96 ? 162 CYS A CB 1 ATOM 1009 S SG . CYS A 1 138 ? 28.158 106.931 47.474 1.00 85.25 ? 162 CYS A SG 1 ATOM 1010 N N . ASN A 1 139 ? 27.551 104.728 50.474 1.00 93.10 ? 163 ASN A N 1 ATOM 1011 C CA . ASN A 1 139 ? 26.470 103.734 50.594 1.00 96.78 ? 163 ASN A CA 1 ATOM 1012 C C . ASN A 1 139 ? 25.371 103.975 49.554 1.00 95.43 ? 163 ASN A C 1 ATOM 1013 O O . ASN A 1 139 ? 24.277 104.438 49.868 1.00 93.89 ? 163 ASN A O 1 ATOM 1014 C CB . ASN A 1 139 ? 25.886 103.707 52.018 1.00 104.64 ? 163 ASN A CB 1 ATOM 1015 C CG . ASN A 1 139 ? 26.852 103.099 53.034 1.00 114.57 ? 163 ASN A CG 1 ATOM 1016 O OD1 . ASN A 1 139 ? 27.973 102.707 52.691 1.00 119.33 ? 163 ASN A OD1 1 ATOM 1017 N ND2 . ASN A 1 139 ? 26.421 103.020 54.289 1.00 119.02 ? 163 ASN A ND2 1 ATOM 1018 N N . PRO A 1 140 ? 25.653 103.626 48.294 1.00 92.21 ? 164 PRO A N 1 ATOM 1019 C CA . PRO A 1 140 ? 24.688 103.815 47.213 1.00 93.11 ? 164 PRO A CA 1 ATOM 1020 C C . PRO A 1 140 ? 23.568 102.796 47.161 1.00 96.91 ? 164 PRO A C 1 ATOM 1021 O O . PRO A 1 140 ? 23.646 101.758 47.822 1.00 88.40 ? 164 PRO A O 1 ATOM 1022 C CB . PRO A 1 140 ? 25.556 103.648 45.954 1.00 96.89 ? 164 PRO A CB 1 ATOM 1023 C CG . PRO A 1 140 ? 26.578 102.641 46.361 1.00 98.02 ? 164 PRO A CG 1 ATOM 1024 C CD . PRO A 1 140 ? 26.889 102.974 47.803 1.00 96.31 ? 164 PRO A CD 1 ATOM 1025 N N . PRO A 1 141 ? 22.477 103.121 46.424 1.00 121.85 ? 165 PRO A N 1 ATOM 1026 C CA . PRO A 1 141 ? 21.366 102.174 46.254 1.00 126.97 ? 165 PRO A CA 1 ATOM 1027 C C . PRO A 1 141 ? 21.949 101.158 45.220 1.00 124.55 ? 165 PRO A C 1 ATOM 1028 O O . PRO A 1 141 ? 22.795 101.526 44.382 1.00 135.09 ? 165 PRO A O 1 ATOM 1029 C CB . PRO A 1 141 ? 20.256 103.014 45.645 1.00 125.48 ? 165 PRO A CB 1 ATOM 1030 C CG . PRO A 1 141 ? 20.950 104.179 45.029 1.00 125.81 ? 165 PRO A CG 1 ATOM 1031 C CD . PRO A 1 141 ? 22.097 104.472 45.956 1.00 119.26 ? 165 PRO A CD 1 ATOM 1032 N N . PRO A 1 142 ? 21.461 99.899 45.239 1.00 120.44 ? 166 PRO A N 1 ATOM 1033 C CA . PRO A 1 142 ? 21.940 98.842 44.346 1.00 109.65 ? 166 PRO A CA 1 ATOM 1034 C C . PRO A 1 142 ? 22.131 99.156 42.875 1.00 96.94 ? 166 PRO A C 1 ATOM 1035 O O . PRO A 1 142 ? 23.170 99.684 42.484 1.00 90.90 ? 166 PRO A O 1 ATOM 1036 C CB . PRO A 1 142 ? 20.956 97.694 44.581 1.00 128.39 ? 166 PRO A CB 1 ATOM 1037 C CG . PRO A 1 142 ? 20.451 97.928 45.965 1.00 134.82 ? 166 PRO A CG 1 ATOM 1038 C CD . PRO A 1 142 ? 20.321 99.428 46.049 1.00 134.58 ? 166 PRO A CD 1 ATOM 1039 N N . GLY A 1 143 ? 21.126 98.844 42.066 1.00 87.43 ? 167 GLY A N 1 ATOM 1040 C CA . GLY A 1 143 ? 21.243 99.032 40.625 1.00 85.91 ? 167 GLY A CA 1 ATOM 1041 C C . GLY A 1 143 ? 22.090 97.920 40.006 1.00 89.46 ? 167 GLY A C 1 ATOM 1042 O O . GLY A 1 143 ? 23.054 97.445 40.621 1.00 80.71 ? 167 GLY A O 1 ATOM 1043 N N . LEU A 1 144 ? 21.748 97.517 38.784 1.00 94.10 ? 168 LEU A N 1 ATOM 1044 C CA . LEU A 1 144 ? 22.446 96.412 38.120 1.00 102.58 ? 168 LEU A CA 1 ATOM 1045 C C . LEU A 1 144 ? 22.844 96.755 36.685 1.00 102.73 ? 168 LEU A C 1 ATOM 1046 O O . LEU A 1 144 ? 22.025 97.221 35.902 1.00 105.61 ? 168 LEU A O 1 ATOM 1047 C CB . LEU A 1 144 ? 21.566 95.145 38.139 1.00 119.08 ? 168 LEU A CB 1 ATOM 1048 C CG . LEU A 1 144 ? 21.086 94.600 39.502 1.00 121.73 ? 168 LEU A CG 1 ATOM 1049 C CD1 . LEU A 1 144 ? 19.675 95.098 39.821 1.00 122.82 ? 168 LEU A CD1 1 ATOM 1050 C CD2 . LEU A 1 144 ? 21.117 93.072 39.505 1.00 122.99 ? 168 LEU A CD2 1 ATOM 1051 N N . PRO A 1 145 ? 24.137 96.575 36.346 1.00 94.86 ? 169 PRO A N 1 ATOM 1052 C CA . PRO A 1 145 ? 25.176 96.147 37.291 1.00 88.26 ? 169 PRO A CA 1 ATOM 1053 C C . PRO A 1 145 ? 25.608 97.342 38.124 1.00 81.88 ? 169 PRO A C 1 ATOM 1054 O O . PRO A 1 145 ? 25.076 98.440 37.951 1.00 79.23 ? 169 PRO A O 1 ATOM 1055 C CB . PRO A 1 145 ? 26.291 95.639 36.382 1.00 89.22 ? 169 PRO A CB 1 ATOM 1056 C CG . PRO A 1 145 ? 26.159 96.466 35.156 1.00 93.06 ? 169 PRO A CG 1 ATOM 1057 C CD . PRO A 1 145 ? 24.678 96.763 34.991 1.00 92.65 ? 169 PRO A CD 1 ATOM 1058 N N . SER A 1 146 ? 26.583 97.137 39.007 1.00 73.61 ? 170 SER A N 1 ATOM 1059 C CA . SER A 1 146 ? 27.043 98.194 39.894 1.00 68.81 ? 170 SER A CA 1 ATOM 1060 C C . SER A 1 146 ? 27.346 99.498 39.184 1.00 65.61 ? 170 SER A C 1 ATOM 1061 O O . SER A 1 146 ? 27.975 99.511 38.130 1.00 62.50 ? 170 SER A O 1 ATOM 1062 C CB . SER A 1 146 ? 28.274 97.731 40.681 1.00 71.36 ? 170 SER A CB 1 ATOM 1063 O OG . SER A 1 146 ? 27.894 96.819 41.696 1.00 75.38 ? 170 SER A OG 1 ATOM 1064 N N . PRO A 1 147 ? 26.862 100.611 39.743 1.00 68.44 ? 171 PRO A N 1 ATOM 1065 C CA . PRO A 1 147 ? 27.090 101.937 39.175 1.00 69.78 ? 171 PRO A CA 1 ATOM 1066 C C . PRO A 1 147 ? 28.523 102.410 39.409 1.00 70.10 ? 171 PRO A C 1 ATOM 1067 O O . PRO A 1 147 ? 29.102 102.136 40.459 1.00 73.16 ? 171 PRO A O 1 ATOM 1068 C CB . PRO A 1 147 ? 26.117 102.830 39.960 1.00 58.10 ? 171 PRO A CB 1 ATOM 1069 C CG . PRO A 1 147 ? 25.936 102.126 41.259 1.00 54.77 ? 171 PRO A CG 1 ATOM 1070 C CD . PRO A 1 147 ? 25.941 100.671 40.896 1.00 57.86 ? 171 PRO A CD 1 ATOM 1071 N N . VAL A 1 148 ? 29.086 103.108 38.424 1.00 59.22 ? 172 VAL A N 1 ATOM 1072 C CA . VAL A 1 148 ? 30.396 103.745 38.575 1.00 55.65 ? 172 VAL A CA 1 ATOM 1073 C C . VAL A 1 148 ? 30.163 104.956 39.500 1.00 55.22 ? 172 VAL A C 1 ATOM 1074 O O . VAL A 1 148 ? 29.184 105.696 39.356 1.00 56.14 ? 172 VAL A O 1 ATOM 1075 C CB . VAL A 1 148 ? 30.971 104.205 37.207 1.00 49.23 ? 172 VAL A CB 1 ATOM 1076 C CG1 . VAL A 1 148 ? 32.246 105.026 37.396 1.00 45.63 ? 172 VAL A CG1 1 ATOM 1077 C CG2 . VAL A 1 148 ? 31.262 102.981 36.339 1.00 47.99 ? 172 VAL A CG2 1 ATOM 1078 N N . ILE A 1 149 ? 31.062 105.143 40.457 1.00 54.82 ? 173 ILE A N 1 ATOM 1079 C CA . ILE A 1 149 ? 30.914 106.194 41.445 1.00 57.21 ? 173 ILE A CA 1 ATOM 1080 C C . ILE A 1 149 ? 32.049 107.201 41.426 1.00 57.08 ? 173 ILE A C 1 ATOM 1081 O O . ILE A 1 149 ? 33.197 106.856 41.129 1.00 56.21 ? 173 ILE A O 1 ATOM 1082 C CB . ILE A 1 149 ? 30.805 105.560 42.879 1.00 62.26 ? 173 ILE A CB 1 ATOM 1083 C CG1 . ILE A 1 149 ? 29.488 104.782 42.997 1.00 65.07 ? 173 ILE A CG1 1 ATOM 1084 C CG2 . ILE A 1 149 ? 30.919 106.637 43.968 1.00 61.63 ? 173 ILE A CG2 1 ATOM 1085 C CD1 . ILE A 1 149 ? 29.401 103.845 44.196 1.00 75.83 ? 173 ILE A CD1 1 ATOM 1086 N N . PHE A 1 150 ? 31.700 108.460 41.688 1.00 61.20 ? 174 PHE A N 1 ATOM 1087 C CA . PHE A 1 150 ? 32.672 109.543 41.817 1.00 65.51 ? 174 PHE A CA 1 ATOM 1088 C C . PHE A 1 150 ? 32.096 110.650 42.682 1.00 65.60 ? 174 PHE A C 1 ATOM 1089 O O . PHE A 1 150 ? 30.893 110.685 42.944 1.00 61.41 ? 174 PHE A O 1 ATOM 1090 C CB . PHE A 1 150 ? 33.120 110.101 40.469 1.00 76.19 ? 174 PHE A CB 1 ATOM 1091 C CG . PHE A 1 150 ? 32.017 110.248 39.478 1.00 86.50 ? 174 PHE A CG 1 ATOM 1092 C CD1 . PHE A 1 150 ? 31.122 111.308 39.561 1.00 90.94 ? 174 PHE A CD1 1 ATOM 1093 C CD2 . PHE A 1 150 ? 31.870 109.318 38.455 1.00 90.68 ? 174 PHE A CD2 1 ATOM 1094 C CE1 . PHE A 1 150 ? 30.089 111.442 38.636 1.00 92.61 ? 174 PHE A CE1 1 ATOM 1095 C CE2 . PHE A 1 150 ? 30.847 109.438 37.529 1.00 92.83 ? 174 PHE A CE2 1 ATOM 1096 C CZ . PHE A 1 150 ? 29.951 110.506 37.618 1.00 93.17 ? 174 PHE A CZ 1 ATOM 1097 N N . TRP A 1 151 ? 32.967 111.551 43.126 1.00 70.28 ? 175 TRP A N 1 ATOM 1098 C CA . TRP A 1 151 ? 32.568 112.642 43.995 1.00 72.45 ? 175 TRP A CA 1 ATOM 1099 C C . TRP A 1 151 ? 32.726 113.977 43.290 1.00 75.02 ? 175 TRP A C 1 ATOM 1100 O O . TRP A 1 151 ? 33.707 114.218 42.584 1.00 73.62 ? 175 TRP A O 1 ATOM 1101 C CB . TRP A 1 151 ? 33.388 112.603 45.295 1.00 69.46 ? 175 TRP A CB 1 ATOM 1102 C CG . TRP A 1 151 ? 33.105 111.390 46.160 1.00 69.50 ? 175 TRP A CG 1 ATOM 1103 C CD1 . TRP A 1 151 ? 33.585 110.124 45.981 1.00 70.39 ? 175 TRP A CD1 1 ATOM 1104 C CD2 . TRP A 1 151 ? 32.272 111.339 47.330 1.00 68.98 ? 175 TRP A CD2 1 ATOM 1105 N NE1 . TRP A 1 151 ? 33.105 109.289 46.966 1.00 70.34 ? 175 TRP A NE1 1 ATOM 1106 C CE2 . TRP A 1 151 ? 32.298 110.009 47.805 1.00 69.61 ? 175 TRP A CE2 1 ATOM 1107 C CE3 . TRP A 1 151 ? 31.506 112.289 48.021 1.00 68.71 ? 175 TRP A CE3 1 ATOM 1108 C CZ2 . TRP A 1 151 ? 31.592 109.604 48.940 1.00 70.14 ? 175 TRP A CZ2 1 ATOM 1109 C CZ3 . TRP A 1 151 ? 30.803 111.887 49.150 1.00 69.16 ? 175 TRP A CZ3 1 ATOM 1110 C CH2 . TRP A 1 151 ? 30.852 110.555 49.598 1.00 70.41 ? 175 TRP A CH2 1 ATOM 1111 N N . MET A 1 152 ? 31.728 114.833 43.474 1.00 77.67 ? 176 MET A N 1 ATOM 1112 C CA . MET A 1 152 ? 31.707 116.153 42.860 1.00 79.84 ? 176 MET A CA 1 ATOM 1113 C C . MET A 1 152 ? 31.159 117.170 43.851 1.00 82.29 ? 176 MET A C 1 ATOM 1114 O O . MET A 1 152 ? 30.441 116.810 44.790 1.00 80.87 ? 176 MET A O 1 ATOM 1115 C CB . MET A 1 152 ? 30.768 116.148 41.641 1.00 87.03 ? 176 MET A CB 1 ATOM 1116 C CG . MET A 1 152 ? 31.026 115.040 40.646 1.00 91.35 ? 176 MET A CG 1 ATOM 1117 S SD . MET A 1 152 ? 32.326 115.461 39.486 1.00 94.55 ? 176 MET A SD 1 ATOM 1118 C CE . MET A 1 152 ? 31.351 115.926 38.072 1.00 95.72 ? 176 MET A CE 1 ATOM 1119 N N . SER A 1 153 ? 31.536 118.431 43.653 1.00 88.61 ? 177 SER A N 1 ATOM 1120 C CA . SER A 1 153 ? 30.949 119.530 44.415 1.00 91.35 ? 177 SER A CA 1 ATOM 1121 C C . SER A 1 153 ? 29.472 119.618 43.951 1.00 88.63 ? 177 SER A C 1 ATOM 1122 O O . SER A 1 153 ? 29.145 119.233 42.823 1.00 88.91 ? 177 SER A O 1 ATOM 1123 C CB . SER A 1 153 ? 31.662 120.843 44.088 1.00 110.99 ? 177 SER A CB 1 ATOM 1124 O OG . SER A 1 153 ? 31.023 121.947 44.714 1.00 120.09 ? 177 SER A OG 1 ATOM 1125 N N . SER A 1 154 ? 28.590 120.116 44.818 1.00 85.23 ? 178 SER A N 1 ATOM 1126 C CA . SER A 1 154 ? 27.165 120.219 44.492 1.00 81.39 ? 178 SER A CA 1 ATOM 1127 C C . SER A 1 154 ? 26.897 121.108 43.282 1.00 80.62 ? 178 SER A C 1 ATOM 1128 O O . SER A 1 154 ? 25.811 121.068 42.710 1.00 79.58 ? 178 SER A O 1 ATOM 1129 C CB . SER A 1 154 ? 26.365 120.718 45.700 1.00 85.18 ? 178 SER A CB 1 ATOM 1130 O OG . SER A 1 154 ? 26.719 122.046 46.041 1.00 86.26 ? 178 SER A OG 1 ATOM 1131 N N . SER A 1 155 ? 27.893 121.907 42.906 1.00 78.97 ? 179 SER A N 1 ATOM 1132 C CA . SER A 1 155 ? 27.807 122.771 41.738 1.00 87.50 ? 179 SER A CA 1 ATOM 1133 C C . SER A 1 155 ? 28.606 122.196 40.554 1.00 88.68 ? 179 SER A C 1 ATOM 1134 O O . SER A 1 155 ? 29.024 122.926 39.652 1.00 80.76 ? 179 SER A O 1 ATOM 1135 C CB . SER A 1 155 ? 28.274 124.185 42.076 1.00 97.81 ? 179 SER A CB 1 ATOM 1136 O OG . SER A 1 155 ? 29.547 124.168 42.689 1.00 108.97 ? 179 SER A OG 1 ATOM 1137 N N . MET A 1 156 ? 28.821 120.880 40.591 1.00 104.28 ? 180 MET A N 1 ATOM 1138 C CA . MET A 1 156 ? 29.463 120.100 39.522 1.00 109.31 ? 180 MET A CA 1 ATOM 1139 C C . MET A 1 156 ? 30.957 120.258 39.262 1.00 110.69 ? 180 MET A C 1 ATOM 1140 O O . MET A 1 156 ? 31.440 119.973 38.157 1.00 116.17 ? 180 MET A O 1 ATOM 1141 C CB . MET A 1 156 ? 28.660 120.247 38.208 1.00 105.99 ? 180 MET A CB 1 ATOM 1142 C CG . MET A 1 156 ? 27.250 119.643 38.254 1.00 106.97 ? 180 MET A CG 1 ATOM 1143 S SD . MET A 1 156 ? 27.210 117.836 38.140 1.00 107.06 ? 180 MET A SD 1 ATOM 1144 C CE . MET A 1 156 ? 27.240 117.366 39.876 1.00 107.15 ? 180 MET A CE 1 ATOM 1145 N N . GLU A 1 157 ? 31.690 120.712 40.278 1.00 95.38 ? 181 GLU A N 1 ATOM 1146 C CA . GLU A 1 157 ? 33.145 120.782 40.166 1.00 90.68 ? 181 GLU A CA 1 ATOM 1147 C C . GLU A 1 157 ? 33.728 119.444 40.631 1.00 81.64 ? 181 GLU A C 1 ATOM 1148 O O . GLU A 1 157 ? 33.324 118.903 41.671 1.00 69.05 ? 181 GLU A O 1 ATOM 1149 C CB . GLU A 1 157 ? 33.739 121.904 41.018 1.00 132.52 ? 181 GLU A CB 1 ATOM 1150 C CG . GLU A 1 157 ? 33.411 123.305 40.536 1.00 159.83 ? 181 GLU A CG 1 ATOM 1151 C CD . GLU A 1 157 ? 32.247 123.917 41.292 1.00 171.91 ? 181 GLU A CD 1 ATOM 1152 O OE1 . GLU A 1 157 ? 32.268 123.891 42.546 1.00 175.27 ? 181 GLU A OE1 1 ATOM 1153 O OE2 . GLU A 1 157 ? 31.317 124.431 40.633 1.00 175.61 ? 181 GLU A OE2 1 ATOM 1154 N N . PRO A 1 158 ? 34.685 118.891 39.859 1.00 90.16 ? 182 PRO A N 1 ATOM 1155 C CA . PRO A 1 158 ? 35.317 117.611 40.208 1.00 88.98 ? 182 PRO A CA 1 ATOM 1156 C C . PRO A 1 158 ? 36.232 117.732 41.422 1.00 84.77 ? 182 PRO A C 1 ATOM 1157 O O . PRO A 1 158 ? 37.073 118.631 41.480 1.00 86.02 ? 182 PRO A O 1 ATOM 1158 C CB . PRO A 1 158 ? 36.089 117.235 38.946 1.00 106.83 ? 182 PRO A CB 1 ATOM 1159 C CG . PRO A 1 158 ? 36.395 118.543 38.300 1.00 110.24 ? 182 PRO A CG 1 ATOM 1160 C CD . PRO A 1 158 ? 35.228 119.446 38.602 1.00 105.50 ? 182 PRO A CD 1 ATOM 1161 N N . ILE A 1 159 ? 36.057 116.831 42.391 1.00 88.22 ? 183 ILE A N 1 ATOM 1162 C CA . ILE A 1 159 ? 36.878 116.822 43.606 1.00 88.50 ? 183 ILE A CA 1 ATOM 1163 C C . ILE A 1 159 ? 38.190 116.107 43.295 1.00 87.63 ? 183 ILE A C 1 ATOM 1164 O O . ILE A 1 159 ? 38.203 114.935 42.910 1.00 86.05 ? 183 ILE A O 1 ATOM 1165 C CB . ILE A 1 159 ? 36.155 116.100 44.777 1.00 81.12 ? 183 ILE A CB 1 ATOM 1166 C CG1 . ILE A 1 159 ? 34.774 116.727 45.028 1.00 79.17 ? 183 ILE A CG1 1 ATOM 1167 C CG2 . ILE A 1 159 ? 37.020 116.126 46.032 1.00 80.39 ? 183 ILE A CG2 1 ATOM 1168 C CD1 . ILE A 1 159 ? 34.745 118.217 45.435 1.00 80.04 ? 183 ILE A CD1 1 ATOM 1169 N N . THR A 1 160 ? 39.294 116.830 43.451 1.00 88.62 ? 184 THR A N 1 ATOM 1170 C CA . THR A 1 160 ? 40.619 116.285 43.153 1.00 101.10 ? 184 THR A CA 1 ATOM 1171 C C . THR A 1 160 ? 41.071 115.304 44.225 1.00 101.33 ? 184 THR A C 1 ATOM 1172 O O . THR A 1 160 ? 40.900 115.541 45.426 1.00 97.36 ? 184 THR A O 1 ATOM 1173 C CB . THR A 1 160 ? 41.662 117.411 42.968 1.00 110.99 ? 184 THR A CB 1 ATOM 1174 O OG1 . THR A 1 160 ? 41.396 118.466 43.898 1.00 118.04 ? 184 THR A OG1 1 ATOM 1175 C CG2 . THR A 1 160 ? 41.605 117.967 41.545 1.00 117.68 ? 184 THR A CG2 1 ATOM 1176 N N . GLN A 1 161 ? 41.642 114.193 43.773 1.00 120.87 ? 185 GLN A N 1 ATOM 1177 C CA . GLN A 1 161 ? 42.063 113.129 44.670 1.00 122.98 ? 185 GLN A CA 1 ATOM 1178 C C . GLN A 1 161 ? 43.576 112.975 44.719 1.00 125.62 ? 185 GLN A C 1 ATOM 1179 O O . GLN A 1 161 ? 44.265 113.228 43.730 1.00 131.89 ? 185 GLN A O 1 ATOM 1180 C CB . GLN A 1 161 ? 41.401 111.803 44.245 1.00 103.42 ? 185 GLN A CB 1 ATOM 1181 C CG . GLN A 1 161 ? 39.867 111.831 44.263 1.00 93.42 ? 185 GLN A CG 1 ATOM 1182 C CD . GLN A 1 161 ? 39.235 110.440 44.297 1.00 89.97 ? 185 GLN A CD 1 ATOM 1183 O OE1 . GLN A 1 161 ? 39.814 109.459 43.817 1.00 89.11 ? 185 GLN A OE1 1 ATOM 1184 N NE2 . GLN A 1 161 ? 38.032 110.354 44.857 1.00 88.25 ? 185 GLN A NE2 1 ATOM 1185 N N . ASP A 1 162 ? 44.085 112.582 45.885 1.00 104.40 ? 186 ASP A N 1 ATOM 1186 C CA . ASP A 1 162 ? 45.520 112.379 46.086 1.00 98.45 ? 186 ASP A CA 1 ATOM 1187 C C . ASP A 1 162 ? 45.771 111.281 47.118 1.00 96.30 ? 186 ASP A C 1 ATOM 1188 O O . ASP A 1 162 ? 44.832 110.601 47.537 1.00 89.47 ? 186 ASP A O 1 ATOM 1189 C CB . ASP A 1 162 ? 46.201 113.697 46.516 1.00 103.77 ? 186 ASP A CB 1 ATOM 1190 C CG . ASP A 1 162 ? 45.432 114.445 47.599 1.00 108.29 ? 186 ASP A CG 1 ATOM 1191 O OD1 . ASP A 1 162 ? 45.604 115.684 47.700 1.00 111.11 ? 186 ASP A OD1 1 ATOM 1192 O OD2 . ASP A 1 162 ? 44.665 113.803 48.350 1.00 111.12 ? 186 ASP A OD2 1 ATOM 1193 N N . LYS A 1 163 ? 47.036 111.097 47.504 1.00 106.66 ? 187 LYS A N 1 ATOM 1194 C CA . LYS A 1 163 ? 47.411 110.101 48.512 1.00 106.21 ? 187 LYS A CA 1 ATOM 1195 C C . LYS A 1 163 ? 46.732 110.379 49.860 1.00 103.76 ? 187 LYS A C 1 ATOM 1196 O O . LYS A 1 163 ? 46.509 109.460 50.654 1.00 107.64 ? 187 LYS A O 1 ATOM 1197 C CB . LYS A 1 163 ? 48.940 110.046 48.695 1.00 114.77 ? 187 LYS A CB 1 ATOM 1198 C CG . LYS A 1 163 ? 49.695 109.462 47.494 1.00 118.97 ? 187 LYS A CG 1 ATOM 1199 C CD . LYS A 1 163 ? 51.055 108.856 47.881 1.00 121.26 ? 187 LYS A CD 1 ATOM 1200 C CE . LYS A 1 163 ? 50.929 107.389 48.326 1.00 122.28 ? 187 LYS A CE 1 ATOM 1201 N NZ . LYS A 1 163 ? 52.247 106.703 48.521 1.00 121.74 ? 187 LYS A NZ 1 ATOM 1202 N N . ARG A 1 164 ? 46.394 111.640 50.110 1.00 88.41 ? 188 ARG A N 1 ATOM 1203 C CA . ARG A 1 164 ? 45.728 112.016 51.347 1.00 82.97 ? 188 ARG A CA 1 ATOM 1204 C C . ARG A 1 164 ? 44.225 111.720 51.283 1.00 80.94 ? 188 ARG A C 1 ATOM 1205 O O . ARG A 1 164 ? 43.668 111.125 52.210 1.00 77.20 ? 188 ARG A O 1 ATOM 1206 C CB . ARG A 1 164 ? 45.960 113.512 51.631 1.00 83.84 ? 188 ARG A CB 1 ATOM 1207 C CG . ARG A 1 164 ? 45.469 113.998 52.994 1.00 87.10 ? 188 ARG A CG 1 ATOM 1208 C CD . ARG A 1 164 ? 45.696 115.498 53.154 1.00 90.03 ? 188 ARG A CD 1 ATOM 1209 N NE . ARG A 1 164 ? 44.956 116.274 52.157 1.00 92.10 ? 188 ARG A NE 1 ATOM 1210 C CZ . ARG A 1 164 ? 43.745 116.801 52.350 1.00 92.86 ? 188 ARG A CZ 1 ATOM 1211 N NH1 . ARG A 1 164 ? 43.116 116.650 53.513 1.00 91.97 ? 188 ARG A NH1 1 ATOM 1212 N NH2 . ARG A 1 164 ? 43.157 117.481 51.370 1.00 92.95 ? 188 ARG A NH2 1 ATOM 1213 N N . VAL A 1 165 ? 43.586 112.116 50.178 1.00 84.57 ? 189 VAL A N 1 ATOM 1214 C CA . VAL A 1 165 ? 42.136 111.968 50.005 1.00 87.74 ? 189 VAL A CA 1 ATOM 1215 C C . VAL A 1 165 ? 41.786 111.206 48.730 1.00 86.58 ? 189 VAL A C 1 ATOM 1216 O O . VAL A 1 165 ? 42.107 111.638 47.621 1.00 88.71 ? 189 VAL A O 1 ATOM 1217 C CB . VAL A 1 165 ? 41.445 113.362 49.969 1.00 90.41 ? 189 VAL A CB 1 ATOM 1218 C CG1 . VAL A 1 165 ? 39.944 113.207 49.799 1.00 91.97 ? 189 VAL A CG1 1 ATOM 1219 C CG2 . VAL A 1 165 ? 41.743 114.133 51.244 1.00 92.43 ? 189 VAL A CG2 1 ATOM 1220 N N . SER A 1 166 ? 41.120 110.069 48.903 1.00 79.84 ? 190 SER A N 1 ATOM 1221 C CA . SER A 1 166 ? 40.750 109.218 47.784 1.00 73.62 ? 190 SER A CA 1 ATOM 1222 C C . SER A 1 166 ? 39.538 108.361 48.133 1.00 70.67 ? 190 SER A C 1 ATOM 1223 O O . SER A 1 166 ? 39.182 108.219 49.308 1.00 67.39 ? 190 SER A O 1 ATOM 1224 C CB . SER A 1 166 ? 41.935 108.314 47.412 1.00 75.66 ? 190 SER A CB 1 ATOM 1225 O OG . SER A 1 166 ? 41.668 107.585 46.228 1.00 79.44 ? 190 SER A OG 1 ATOM 1226 N N . GLN A 1 167 ? 38.899 107.795 47.110 1.00 68.28 ? 191 GLN A N 1 ATOM 1227 C CA . GLN A 1 167 ? 37.745 106.948 47.343 1.00 67.01 ? 191 GLN A CA 1 ATOM 1228 C C . GLN A 1 167 ? 38.072 105.462 47.255 1.00 67.82 ? 191 GLN A C 1 ATOM 1229 O O . GLN A 1 167 ? 38.931 105.039 46.472 1.00 69.44 ? 191 GLN A O 1 ATOM 1230 C CB . GLN A 1 167 ? 36.613 107.269 46.343 1.00 64.69 ? 191 GLN A CB 1 ATOM 1231 C CG . GLN A 1 167 ? 36.807 106.727 44.934 1.00 61.88 ? 191 GLN A CG 1 ATOM 1232 C CD . GLN A 1 167 ? 35.628 107.024 44.022 1.00 60.49 ? 191 GLN A CD 1 ATOM 1233 O OE1 . GLN A 1 167 ? 35.345 108.178 43.709 1.00 60.92 ? 191 GLN A OE1 1 ATOM 1234 N NE2 . GLN A 1 167 ? 34.938 105.980 43.593 1.00 59.87 ? 191 GLN A NE2 1 ATOM 1235 N N . GLY A 1 168 ? 37.394 104.687 48.099 1.00 65.89 ? 192 GLY A N 1 ATOM 1236 C CA . GLY A 1 168 ? 37.513 103.241 48.054 1.00 62.76 ? 192 GLY A CA 1 ATOM 1237 C C . GLY A 1 168 ? 36.588 102.688 46.971 1.00 60.94 ? 192 GLY A C 1 ATOM 1238 O O . GLY A 1 168 ? 35.726 103.405 46.449 1.00 62.21 ? 192 GLY A O 1 ATOM 1239 N N . HIS A 1 169 ? 36.761 101.410 46.640 1.00 54.92 ? 193 HIS A N 1 ATOM 1240 C CA . HIS A 1 169 ? 35.976 100.759 45.599 1.00 56.99 ? 193 HIS A CA 1 ATOM 1241 C C . HIS A 1 169 ? 34.494 100.662 45.947 1.00 58.54 ? 193 HIS A C 1 ATOM 1242 O O . HIS A 1 169 ? 33.658 100.478 45.067 1.00 54.59 ? 193 HIS A O 1 ATOM 1243 C CB . HIS A 1 169 ? 36.556 99.383 45.289 1.00 65.21 ? 193 HIS A CB 1 ATOM 1244 C CG . HIS A 1 169 ? 35.990 98.758 44.055 1.00 69.75 ? 193 HIS A CG 1 ATOM 1245 N ND1 . HIS A 1 169 ? 35.005 97.794 44.093 1.00 70.82 ? 193 HIS A ND1 1 ATOM 1246 C CD2 . HIS A 1 169 ? 36.267 98.963 42.744 1.00 71.68 ? 193 HIS A CD2 1 ATOM 1247 C CE1 . HIS A 1 169 ? 34.705 97.427 42.860 1.00 72.07 ? 193 HIS A CE1 1 ATOM 1248 N NE2 . HIS A 1 169 ? 35.456 98.121 42.023 1.00 73.67 ? 193 HIS A NE2 1 ATOM 1249 N N . ASN A 1 170 ? 34.179 100.782 47.233 1.00 77.29 ? 194 ASN A N 1 ATOM 1250 C CA . ASN A 1 170 ? 32.790 100.775 47.694 1.00 84.19 ? 194 ASN A CA 1 ATOM 1251 C C . ASN A 1 170 ? 32.151 102.162 47.526 1.00 86.34 ? 194 ASN A C 1 ATOM 1252 O O . ASN A 1 170 ? 30.945 102.329 47.738 1.00 92.13 ? 194 ASN A O 1 ATOM 1253 C CB . ASN A 1 170 ? 32.715 100.343 49.161 1.00 79.78 ? 194 ASN A CB 1 ATOM 1254 C CG . ASN A 1 170 ? 33.397 101.321 50.103 1.00 77.96 ? 194 ASN A CG 1 ATOM 1255 O OD1 . ASN A 1 170 ? 34.423 101.925 49.773 1.00 76.09 ? 194 ASN A OD1 1 ATOM 1256 N ND2 . ASN A 1 170 ? 32.838 101.464 51.295 1.00 77.52 ? 194 ASN A ND2 1 ATOM 1257 N N . GLY A 1 171 ? 32.977 103.146 47.162 1.00 78.84 ? 195 GLY A N 1 ATOM 1258 C CA . GLY A 1 171 ? 32.502 104.503 46.931 1.00 71.58 ? 195 GLY A CA 1 ATOM 1259 C C . GLY A 1 171 ? 32.720 105.499 48.052 1.00 66.70 ? 195 GLY A C 1 ATOM 1260 O O . GLY A 1 171 ? 32.559 106.707 47.852 1.00 67.26 ? 195 GLY A O 1 ATOM 1261 N N . ASP A 1 172 ? 33.069 105.001 49.236 1.00 64.13 ? 196 ASP A N 1 ATOM 1262 C CA . ASP A 1 172 ? 33.324 105.865 50.394 1.00 62.85 ? 196 ASP A CA 1 ATOM 1263 C C . ASP A 1 172 ? 34.537 106.750 50.135 1.00 59.69 ? 196 ASP A C 1 ATOM 1264 O O . ASP A 1 172 ? 35.485 106.341 49.451 1.00 56.23 ? 196 ASP A O 1 ATOM 1265 C CB . ASP A 1 172 ? 33.556 105.022 51.652 1.00 75.35 ? 196 ASP A CB 1 ATOM 1266 C CG . ASP A 1 172 ? 32.298 104.302 52.116 1.00 84.55 ? 196 ASP A CG 1 ATOM 1267 O OD1 . ASP A 1 172 ? 32.380 103.538 53.104 1.00 88.00 ? 196 ASP A OD1 1 ATOM 1268 O OD2 . ASP A 1 172 ? 31.226 104.497 51.496 1.00 88.62 ? 196 ASP A OD2 1 ATOM 1269 N N . LEU A 1 173 ? 34.498 107.968 50.672 1.00 59.90 ? 197 LEU A N 1 ATOM 1270 C CA . LEU A 1 173 ? 35.595 108.925 50.492 1.00 65.49 ? 197 LEU A CA 1 ATOM 1271 C C . LEU A 1 173 ? 36.440 108.952 51.753 1.00 69.92 ? 197 LEU A C 1 ATOM 1272 O O . LEU A 1 173 ? 35.931 109.206 52.850 1.00 70.69 ? 197 LEU A O 1 ATOM 1273 C CB . LEU A 1 173 ? 35.040 110.319 50.171 1.00 68.53 ? 197 LEU A CB 1 ATOM 1274 C CG . LEU A 1 173 ? 36.035 111.421 49.771 1.00 66.00 ? 197 LEU A CG 1 ATOM 1275 C CD1 . LEU A 1 173 ? 36.657 111.137 48.410 1.00 63.75 ? 197 LEU A CD1 1 ATOM 1276 C CD2 . LEU A 1 173 ? 35.323 112.759 49.760 1.00 65.05 ? 197 LEU A CD2 1 ATOM 1277 N N . TYR A 1 174 ? 37.734 108.712 51.581 1.00 74.50 ? 198 TYR A N 1 ATOM 1278 C CA . TYR A 1 174 ? 38.648 108.591 52.708 1.00 78.25 ? 198 TYR A CA 1 ATOM 1279 C C . TYR A 1 174 ? 39.633 109.724 52.920 1.00 82.81 ? 198 TYR A C 1 ATOM 1280 O O . TYR A 1 174 ? 40.478 110.002 52.058 1.00 85.65 ? 198 TYR A O 1 ATOM 1281 C CB . TYR A 1 174 ? 39.435 107.267 52.592 1.00 78.37 ? 198 TYR A CB 1 ATOM 1282 C CG . TYR A 1 174 ? 38.591 106.017 52.733 1.00 73.60 ? 198 TYR A CG 1 ATOM 1283 C CD1 . TYR A 1 174 ? 38.037 105.393 51.618 1.00 71.95 ? 198 TYR A CD1 1 ATOM 1284 C CD2 . TYR A 1 174 ? 38.350 105.460 53.989 1.00 71.51 ? 198 TYR A CD2 1 ATOM 1285 C CE1 . TYR A 1 174 ? 37.267 104.246 51.748 1.00 71.83 ? 198 TYR A CE1 1 ATOM 1286 C CE2 . TYR A 1 174 ? 37.580 104.312 54.132 1.00 71.76 ? 198 TYR A CE2 1 ATOM 1287 C CZ . TYR A 1 174 ? 37.042 103.710 53.009 1.00 71.92 ? 198 TYR A CZ 1 ATOM 1288 O OH . TYR A 1 174 ? 36.280 102.575 53.144 1.00 72.14 ? 198 TYR A OH 1 ATOM 1289 N N . PHE A 1 175 ? 39.498 110.381 54.071 1.00 85.58 ? 199 PHE A N 1 ATOM 1290 C CA . PHE A 1 175 ? 40.416 111.434 54.470 1.00 88.60 ? 199 PHE A CA 1 ATOM 1291 C C . PHE A 1 175 ? 41.420 110.850 55.469 1.00 89.54 ? 199 PHE A C 1 ATOM 1292 O O . PHE A 1 175 ? 41.051 110.516 56.602 1.00 85.03 ? 199 PHE A O 1 ATOM 1293 C CB . PHE A 1 175 ? 39.683 112.598 55.147 1.00 98.86 ? 199 PHE A CB 1 ATOM 1294 C CG . PHE A 1 175 ? 38.693 113.296 54.258 1.00 107.57 ? 199 PHE A CG 1 ATOM 1295 C CD1 . PHE A 1 175 ? 37.363 112.887 54.218 1.00 111.28 ? 199 PHE A CD1 1 ATOM 1296 C CD2 . PHE A 1 175 ? 39.088 114.367 53.463 1.00 110.89 ? 199 PHE A CD2 1 ATOM 1297 C CE1 . PHE A 1 175 ? 36.441 113.533 53.394 1.00 112.44 ? 199 PHE A CE1 1 ATOM 1298 C CE2 . PHE A 1 175 ? 38.173 115.018 52.634 1.00 112.25 ? 199 PHE A CE2 1 ATOM 1299 C CZ . PHE A 1 175 ? 36.847 114.602 52.603 1.00 112.32 ? 199 PHE A CZ 1 ATOM 1300 N N . SER A 1 176 ? 42.675 110.710 55.038 1.00 92.25 ? 200 SER A N 1 ATOM 1301 C CA . SER A 1 176 ? 43.750 110.228 55.920 1.00 95.96 ? 200 SER A CA 1 ATOM 1302 C C . SER A 1 176 ? 43.840 111.220 57.086 1.00 95.37 ? 200 SER A C 1 ATOM 1303 O O . SER A 1 176 ? 43.692 110.839 58.254 1.00 96.08 ? 200 SER A O 1 ATOM 1304 C CB . SER A 1 176 ? 45.066 110.157 55.156 1.00 110.14 ? 200 SER A CB 1 ATOM 1305 O OG . SER A 1 176 ? 44.981 109.208 54.108 1.00 114.48 ? 200 SER A OG 1 ATOM 1306 N N . ASN A 1 177 ? 44.103 112.483 56.749 1.00 109.73 ? 201 ASN A N 1 ATOM 1307 C CA . ASN A 1 177 ? 44.058 113.579 57.714 1.00 108.89 ? 201 ASN A CA 1 ATOM 1308 C C . ASN A 1 177 ? 43.302 114.759 57.076 1.00 109.31 ? 201 ASN A C 1 ATOM 1309 O O . ASN A 1 177 ? 43.535 115.114 55.914 1.00 110.94 ? 201 ASN A O 1 ATOM 1310 C CB . ASN A 1 177 ? 45.445 114.019 58.173 1.00 99.65 ? 201 ASN A CB 1 ATOM 1311 C CG . ASN A 1 177 ? 46.382 114.323 57.023 1.00 99.40 ? 201 ASN A CG 1 ATOM 1312 O OD1 . ASN A 1 177 ? 47.017 113.422 56.465 1.00 98.65 ? 201 ASN A OD1 1 ATOM 1313 N ND2 . ASN A 1 177 ? 46.475 115.598 56.659 1.00 99.65 ? 201 ASN A ND2 1 ATOM 1314 N N . VAL A 1 178 ? 42.383 115.346 57.838 1.00 115.91 ? 202 VAL A N 1 ATOM 1315 C CA . VAL A 1 178 ? 41.589 116.468 57.352 1.00 116.98 ? 202 VAL A CA 1 ATOM 1316 C C . VAL A 1 178 ? 42.336 117.794 57.506 1.00 123.31 ? 202 VAL A C 1 ATOM 1317 O O . VAL A 1 178 ? 42.660 118.218 58.621 1.00 131.10 ? 202 VAL A O 1 ATOM 1318 C CB . VAL A 1 178 ? 40.219 116.552 58.097 1.00 97.35 ? 202 VAL A CB 1 ATOM 1319 C CG1 . VAL A 1 178 ? 39.459 117.798 57.672 1.00 88.55 ? 202 VAL A CG1 1 ATOM 1320 C CG2 . VAL A 1 178 ? 39.388 115.304 57.813 1.00 89.11 ? 202 VAL A CG2 1 ATOM 1321 N N . MET A 1 179 ? 42.623 118.429 56.370 1.00 119.35 ? 203 MET A N 1 ATOM 1322 C CA . MET A 1 179 ? 43.304 119.722 56.353 1.00 119.90 ? 203 MET A CA 1 ATOM 1323 C C . MET A 1 179 ? 42.282 120.859 56.459 1.00 118.56 ? 203 MET A C 1 ATOM 1324 O O . MET A 1 179 ? 41.098 120.623 56.724 1.00 118.32 ? 203 MET A O 1 ATOM 1325 C CB . MET A 1 179 ? 44.127 119.883 55.064 1.00 114.15 ? 203 MET A CB 1 ATOM 1326 C CG . MET A 1 179 ? 45.297 118.910 54.940 1.00 113.68 ? 203 MET A CG 1 ATOM 1327 S SD . MET A 1 179 ? 46.254 119.150 53.424 1.00 113.87 ? 203 MET A SD 1 ATOM 1328 C CE . MET A 1 179 ? 47.418 120.420 53.949 1.00 113.93 ? 203 MET A CE 1 ATOM 1329 N N . LEU A 1 180 ? 42.753 122.091 56.274 1.00 126.33 ? 204 LEU A N 1 ATOM 1330 C CA . LEU A 1 180 ? 41.883 123.262 56.321 1.00 121.70 ? 204 LEU A CA 1 ATOM 1331 C C . LEU A 1 180 ? 41.190 123.520 54.975 1.00 118.63 ? 204 LEU A C 1 ATOM 1332 O O . LEU A 1 180 ? 40.013 123.903 54.940 1.00 121.70 ? 204 LEU A O 1 ATOM 1333 C CB . LEU A 1 180 ? 42.676 124.512 56.770 1.00 127.39 ? 204 LEU A CB 1 ATOM 1334 C CG . LEU A 1 180 ? 44.204 124.590 56.557 1.00 123.69 ? 204 LEU A CG 1 ATOM 1335 C CD1 . LEU A 1 180 ? 44.569 124.876 55.099 1.00 121.31 ? 204 LEU A CD1 1 ATOM 1336 C CD2 . LEU A 1 180 ? 44.792 125.664 57.473 1.00 121.98 ? 204 LEU A CD2 1 ATOM 1337 N N . GLN A 1 181 ? 41.912 123.273 53.879 1.00 96.24 ? 205 GLN A N 1 ATOM 1338 C CA . GLN A 1 181 ? 41.394 123.503 52.529 1.00 95.15 ? 205 GLN A CA 1 ATOM 1339 C C . GLN A 1 181 ? 40.201 122.614 52.159 1.00 93.55 ? 205 GLN A C 1 ATOM 1340 O O . GLN A 1 181 ? 39.508 122.873 51.174 1.00 86.36 ? 205 GLN A O 1 ATOM 1341 C CB . GLN A 1 181 ? 42.517 123.339 51.490 1.00 96.89 ? 205 GLN A CB 1 ATOM 1342 C CG . GLN A 1 181 ? 42.993 121.907 51.278 1.00 101.29 ? 205 GLN A CG 1 ATOM 1343 C CD . GLN A 1 181 ? 43.786 121.735 49.990 1.00 103.50 ? 205 GLN A CD 1 ATOM 1344 O OE1 . GLN A 1 181 ? 44.827 122.364 49.796 1.00 103.57 ? 205 GLN A OE1 1 ATOM 1345 N NE2 . GLN A 1 181 ? 43.293 120.876 49.102 1.00 103.51 ? 205 GLN A NE2 1 ATOM 1346 N N . ASP A 1 182 ? 39.960 121.579 52.961 1.00 108.68 ? 206 ASP A N 1 ATOM 1347 C CA . ASP A 1 182 ? 38.854 120.651 52.725 1.00 117.05 ? 206 ASP A CA 1 ATOM 1348 C C . ASP A 1 182 ? 37.486 121.317 52.900 1.00 118.11 ? 206 ASP A C 1 ATOM 1349 O O . ASP A 1 182 ? 36.441 120.664 52.809 1.00 125.02 ? 206 ASP A O 1 ATOM 1350 C CB . ASP A 1 182 ? 38.994 119.418 53.623 1.00 126.71 ? 206 ASP A CB 1 ATOM 1351 C CG . ASP A 1 182 ? 40.236 118.590 53.291 1.00 126.55 ? 206 ASP A CG 1 ATOM 1352 O OD1 . ASP A 1 182 ? 40.664 117.795 54.159 1.00 125.58 ? 206 ASP A OD1 1 ATOM 1353 O OD2 . ASP A 1 182 ? 40.779 118.731 52.167 1.00 125.68 ? 206 ASP A OD2 1 ATOM 1354 N N . MET A 1 183 ? 37.509 122.624 53.159 1.00 117.57 ? 207 MET A N 1 ATOM 1355 C CA . MET A 1 183 ? 36.282 123.405 53.241 1.00 115.26 ? 207 MET A CA 1 ATOM 1356 C C . MET A 1 183 ? 36.128 124.286 51.990 1.00 111.27 ? 207 MET A C 1 ATOM 1357 O O . MET A 1 183 ? 35.207 125.102 51.908 1.00 100.24 ? 207 MET A O 1 ATOM 1358 C CB . MET A 1 183 ? 36.239 124.242 54.519 1.00 124.27 ? 207 MET A CB 1 ATOM 1359 C CG . MET A 1 183 ? 35.907 123.413 55.753 1.00 137.65 ? 207 MET A CG 1 ATOM 1360 S SD . MET A 1 183 ? 35.599 124.375 57.248 1.00 144.80 ? 207 MET A SD 1 ATOM 1361 C CE . MET A 1 183 ? 34.170 125.370 56.761 1.00 146.56 ? 207 MET A CE 1 ATOM 1362 N N . GLN A 1 184 ? 37.027 124.095 51.019 1.00 119.23 ? 208 GLN A N 1 ATOM 1363 C CA . GLN A 1 184 ? 36.982 124.816 49.742 1.00 123.84 ? 208 GLN A CA 1 ATOM 1364 C C . GLN A 1 184 ? 35.974 124.186 48.764 1.00 122.56 ? 208 GLN A C 1 ATOM 1365 O O . GLN A 1 184 ? 36.001 124.470 47.563 1.00 127.33 ? 208 GLN A O 1 ATOM 1366 C CB . GLN A 1 184 ? 38.372 124.868 49.086 1.00 126.05 ? 208 GLN A CB 1 ATOM 1367 C CG . GLN A 1 184 ? 39.322 125.885 49.714 1.00 127.09 ? 208 GLN A CG 1 ATOM 1368 C CD . GLN A 1 184 ? 40.689 125.930 49.040 1.00 128.06 ? 208 GLN A CD 1 ATOM 1369 O OE1 . GLN A 1 184 ? 40.998 125.115 48.164 1.00 128.58 ? 208 GLN A OE1 1 ATOM 1370 N NE2 . GLN A 1 184 ? 41.517 126.883 49.454 1.00 128.58 ? 208 GLN A NE2 1 ATOM 1371 N N . THR A 1 185 ? 35.095 123.338 49.297 1.00 99.74 ? 209 THR A N 1 ATOM 1372 C CA . THR A 1 185 ? 34.038 122.671 48.534 1.00 92.80 ? 209 THR A CA 1 ATOM 1373 C C . THR A 1 185 ? 33.173 121.790 49.433 1.00 88.41 ? 209 THR A C 1 ATOM 1374 O O . THR A 1 185 ? 33.580 121.437 50.543 1.00 88.73 ? 209 THR A O 1 ATOM 1375 C CB . THR A 1 185 ? 34.621 121.756 47.391 1.00 92.71 ? 209 THR A CB 1 ATOM 1376 O OG1 . THR A 1 185 ? 33.579 120.923 46.866 1.00 89.77 ? 209 THR A OG1 1 ATOM 1377 C CG2 . THR A 1 185 ? 35.757 120.875 47.899 1.00 89.87 ? 209 THR A CG2 1 ATOM 1378 N N . ASP A 1 186 ? 31.955 121.497 48.972 1.00 83.56 ? 210 ASP A N 1 ATOM 1379 C CA . ASP A 1 186 ? 31.100 120.527 49.655 1.00 82.49 ? 210 ASP A CA 1 ATOM 1380 C C . ASP A 1 186 ? 31.241 119.197 48.885 1.00 82.19 ? 210 ASP A C 1 ATOM 1381 O O . ASP A 1 186 ? 31.814 119.166 47.787 1.00 78.01 ? 210 ASP A O 1 ATOM 1382 C CB . ASP A 1 186 ? 29.642 120.976 49.761 1.00 95.45 ? 210 ASP A CB 1 ATOM 1383 C CG . ASP A 1 186 ? 28.990 121.244 48.417 1.00 99.47 ? 210 ASP A CG 1 ATOM 1384 O OD1 . ASP A 1 186 ? 27.763 121.493 48.418 1.00 100.61 ? 210 ASP A OD1 1 ATOM 1385 O OD2 . ASP A 1 186 ? 29.674 121.217 47.367 1.00 101.80 ? 210 ASP A OD2 1 ATOM 1386 N N . TYR A 1 187 ? 30.722 118.110 49.451 1.00 83.74 ? 211 TYR A N 1 ATOM 1387 C CA . TYR A 1 187 ? 30.943 116.795 48.855 1.00 83.05 ? 211 TYR A CA 1 ATOM 1388 C C . TYR A 1 187 ? 29.695 115.951 48.664 1.00 83.06 ? 211 TYR A C 1 ATOM 1389 O O . TYR A 1 187 ? 28.992 115.626 49.623 1.00 80.02 ? 211 TYR A O 1 ATOM 1390 C CB . TYR A 1 187 ? 31.977 116.037 49.713 1.00 81.79 ? 211 TYR A CB 1 ATOM 1391 C CG . TYR A 1 187 ? 33.259 116.814 49.950 1.00 84.87 ? 211 TYR A CG 1 ATOM 1392 C CD1 . TYR A 1 187 ? 33.374 117.701 51.022 1.00 85.72 ? 211 TYR A CD1 1 ATOM 1393 C CD2 . TYR A 1 187 ? 34.351 116.672 49.089 1.00 86.18 ? 211 TYR A CD2 1 ATOM 1394 C CE1 . TYR A 1 187 ? 34.539 118.426 51.232 1.00 86.94 ? 211 TYR A CE1 1 ATOM 1395 C CE2 . TYR A 1 187 ? 35.524 117.395 49.295 1.00 87.41 ? 211 TYR A CE2 1 ATOM 1396 C CZ . TYR A 1 187 ? 35.610 118.270 50.370 1.00 87.40 ? 211 TYR A CZ 1 ATOM 1397 O OH . TYR A 1 187 ? 36.769 118.986 50.583 1.00 88.15 ? 211 TYR A OH 1 ATOM 1398 N N . SER A 1 188 ? 29.423 115.609 47.407 1.00 76.01 ? 212 SER A N 1 ATOM 1399 C CA . SER A 1 188 ? 28.256 114.806 47.068 1.00 78.44 ? 212 SER A CA 1 ATOM 1400 C C . SER A 1 188 ? 28.650 113.560 46.289 1.00 74.03 ? 212 SER A C 1 ATOM 1401 O O . SER A 1 188 ? 29.386 113.641 45.304 1.00 71.30 ? 212 SER A O 1 ATOM 1402 C CB . SER A 1 188 ? 27.258 115.635 46.247 1.00 95.97 ? 212 SER A CB 1 ATOM 1403 O OG . SER A 1 188 ? 27.842 116.075 45.034 1.00 106.47 ? 212 SER A OG 1 ATOM 1404 N N . CYS A 1 189 ? 28.168 112.407 46.749 1.00 76.64 ? 213 CYS A N 1 ATOM 1405 C CA . CYS A 1 189 ? 28.448 111.146 46.078 1.00 73.68 ? 213 CYS A CA 1 ATOM 1406 C C . CYS A 1 189 ? 27.537 110.985 44.866 1.00 73.75 ? 213 CYS A C 1 ATOM 1407 O O . CYS A 1 189 ? 26.317 111.140 44.963 1.00 73.66 ? 213 CYS A O 1 ATOM 1408 C CB . CYS A 1 189 ? 28.256 109.966 47.036 1.00 70.87 ? 213 CYS A CB 1 ATOM 1409 S SG . CYS A 1 189 ? 29.051 108.445 46.434 1.00 73.59 ? 213 CYS A SG 1 ATOM 1410 N N . ASN A 1 190 ? 28.149 110.692 43.724 1.00 72.86 ? 214 ASN A N 1 ATOM 1411 C CA . ASN A 1 190 ? 27.429 110.497 42.470 1.00 71.58 ? 214 ASN A CA 1 ATOM 1412 C C . ASN A 1 190 ? 27.555 109.063 41.977 1.00 69.21 ? 214 ASN A C 1 ATOM 1413 O O . ASN A 1 190 ? 28.611 108.439 42.120 1.00 67.75 ? 214 ASN A O 1 ATOM 1414 C CB . ASN A 1 190 ? 27.974 111.435 41.390 1.00 77.50 ? 214 ASN A CB 1 ATOM 1415 C CG . ASN A 1 190 ? 27.443 112.845 41.517 1.00 82.48 ? 214 ASN A CG 1 ATOM 1416 O OD1 . ASN A 1 190 ? 26.807 113.360 40.597 1.00 84.65 ? 214 ASN A OD1 1 ATOM 1417 N ND2 . ASN A 1 190 ? 27.704 113.482 42.655 1.00 85.02 ? 214 ASN A ND2 1 ATOM 1418 N N . ALA A 1 191 ? 26.476 108.550 41.390 1.00 58.60 ? 215 ALA A N 1 ATOM 1419 C CA . ALA A 1 191 ? 26.478 107.197 40.860 1.00 54.85 ? 215 ALA A CA 1 ATOM 1420 C C . ALA A 1 191 ? 26.012 107.154 39.408 1.00 55.94 ? 215 ALA A C 1 ATOM 1421 O O . ALA A 1 191 ? 24.822 107.303 39.117 1.00 56.55 ? 215 ALA A O 1 ATOM 1422 C CB . ALA A 1 191 ? 25.603 106.296 41.722 1.00 40.91 ? 215 ALA A CB 1 ATOM 1423 N N . ARG A 1 192 ? 26.960 106.961 38.496 1.00 63.26 ? 216 ARG A N 1 ATOM 1424 C CA . ARG A 1 192 ? 26.652 106.870 37.069 1.00 67.20 ? 216 ARG A CA 1 ATOM 1425 C C . ARG A 1 192 ? 26.378 105.410 36.701 1.00 64.84 ? 216 ARG A C 1 ATOM 1426 O O . ARG A 1 192 ? 27.184 104.527 36.976 1.00 64.13 ? 216 ARG A O 1 ATOM 1427 C CB . ARG A 1 192 ? 27.804 107.435 36.228 1.00 83.41 ? 216 ARG A CB 1 ATOM 1428 C CG . ARG A 1 192 ? 27.598 107.332 34.722 1.00 94.60 ? 216 ARG A CG 1 ATOM 1429 C CD . ARG A 1 192 ? 28.838 107.794 33.967 1.00 100.30 ? 216 ARG A CD 1 ATOM 1430 N NE . ARG A 1 192 ? 28.937 107.185 32.642 1.00 102.62 ? 216 ARG A NE 1 ATOM 1431 C CZ . ARG A 1 192 ? 29.584 106.050 32.372 1.00 103.92 ? 216 ARG A CZ 1 ATOM 1432 N NH1 . ARG A 1 192 ? 30.210 105.378 33.337 1.00 103.41 ? 216 ARG A NH1 1 ATOM 1433 N NH2 . ARG A 1 192 ? 29.608 105.581 31.128 1.00 104.60 ? 216 ARG A NH2 1 ATOM 1434 N N . PHE A 1 193 ? 25.229 105.176 36.073 1.00 60.28 ? 217 PHE A N 1 ATOM 1435 C CA . PHE A 1 193 ? 24.798 103.834 35.706 1.00 67.63 ? 217 PHE A CA 1 ATOM 1436 C C . PHE A 1 193 ? 25.243 103.453 34.304 1.00 78.91 ? 217 PHE A C 1 ATOM 1437 O O . PHE A 1 193 ? 25.330 104.304 33.427 1.00 73.97 ? 217 PHE A O 1 ATOM 1438 C CB . PHE A 1 193 ? 23.304 103.704 35.922 1.00 67.39 ? 217 PHE A CB 1 ATOM 1439 C CG . PHE A 1 193 ? 22.903 103.774 37.368 1.00 62.80 ? 217 PHE A CG 1 ATOM 1440 C CD1 . PHE A 1 193 ? 22.666 104.997 37.980 1.00 62.41 ? 217 PHE A CD1 1 ATOM 1441 C CD2 . PHE A 1 193 ? 22.770 102.614 38.123 1.00 62.42 ? 217 PHE A CD2 1 ATOM 1442 C CE1 . PHE A 1 193 ? 22.294 105.068 39.329 1.00 62.34 ? 217 PHE A CE1 1 ATOM 1443 C CE2 . PHE A 1 193 ? 22.401 102.673 39.468 1.00 62.85 ? 217 PHE A CE2 1 ATOM 1444 C CZ . PHE A 1 193 ? 22.164 103.907 40.074 1.00 61.91 ? 217 PHE A CZ 1 ATOM 1445 N N . HIS A 1 194 ? 25.488 102.160 34.102 1.00 127.28 ? 218 HIS A N 1 ATOM 1446 C CA . HIS A 1 194 ? 26.152 101.698 32.888 1.00 149.44 ? 218 HIS A CA 1 ATOM 1447 C C . HIS A 1 194 ? 25.550 101.925 31.522 1.00 161.18 ? 218 HIS A C 1 ATOM 1448 O O . HIS A 1 194 ? 26.214 102.479 30.632 1.00 178.77 ? 218 HIS A O 1 ATOM 1449 C CB . HIS A 1 194 ? 26.550 100.205 33.034 1.00 125.30 ? 218 HIS A CB 1 ATOM 1450 C CG . HIS A 1 194 ? 27.876 99.983 33.707 1.00 114.07 ? 218 HIS A CG 1 ATOM 1451 N ND1 . HIS A 1 194 ? 28.003 99.311 34.906 1.00 108.23 ? 218 HIS A ND1 1 ATOM 1452 C CD2 . HIS A 1 194 ? 29.130 100.346 33.347 1.00 108.66 ? 218 HIS A CD2 1 ATOM 1453 C CE1 . HIS A 1 194 ? 29.278 99.273 35.255 1.00 106.63 ? 218 HIS A CE1 1 ATOM 1454 N NE2 . HIS A 1 194 ? 29.983 99.894 34.326 1.00 107.03 ? 218 HIS A NE2 1 ATOM 1455 N N . PHE A 1 195 ? 24.292 101.532 31.359 1.00 140.90 ? 219 PHE A N 1 ATOM 1456 C CA . PHE A 1 195 ? 23.665 101.595 30.043 1.00 132.96 ? 219 PHE A CA 1 ATOM 1457 C C . PHE A 1 195 ? 22.604 102.674 29.884 1.00 121.01 ? 219 PHE A C 1 ATOM 1458 O O . PHE A 1 195 ? 22.332 103.118 28.762 1.00 116.25 ? 219 PHE A O 1 ATOM 1459 C CB . PHE A 1 195 ? 23.131 100.198 29.678 1.00 169.75 ? 219 PHE A CB 1 ATOM 1460 C CG . PHE A 1 195 ? 24.177 99.107 29.768 1.00 179.10 ? 219 PHE A CG 1 ATOM 1461 C CD1 . PHE A 1 195 ? 25.302 99.121 28.939 1.00 182.85 ? 219 PHE A CD1 1 ATOM 1462 C CD2 . PHE A 1 195 ? 24.039 98.071 30.689 1.00 183.09 ? 219 PHE A CD2 1 ATOM 1463 C CE1 . PHE A 1 195 ? 26.274 98.120 29.024 1.00 183.90 ? 219 PHE A CE1 1 ATOM 1464 C CE2 . PHE A 1 195 ? 25.009 97.061 30.784 1.00 184.25 ? 219 PHE A CE2 1 ATOM 1465 C CZ . PHE A 1 195 ? 26.127 97.088 29.949 1.00 184.38 ? 219 PHE A CZ 1 ATOM 1466 N N . THR A 1 196 ? 22.013 103.093 31.006 1.00 114.24 ? 220 THR A N 1 ATOM 1467 C CA . THR A 1 196 ? 21.052 104.197 30.991 1.00 102.89 ? 220 THR A CA 1 ATOM 1468 C C . THR A 1 196 ? 21.772 105.558 31.068 1.00 98.04 ? 220 THR A C 1 ATOM 1469 O O . THR A 1 196 ? 21.239 106.575 30.629 1.00 96.43 ? 220 THR A O 1 ATOM 1470 C CB . THR A 1 196 ? 20.016 104.106 32.162 1.00 89.37 ? 220 THR A CB 1 ATOM 1471 O OG1 . THR A 1 196 ? 19.539 105.418 32.477 1.00 87.01 ? 220 THR A OG1 1 ATOM 1472 C CG2 . THR A 1 196 ? 20.623 103.489 33.411 1.00 86.92 ? 220 THR A CG2 1 ATOM 1473 N N . HIS A 1 197 ? 22.991 105.553 31.603 1.00 82.26 ? 221 HIS A N 1 ATOM 1474 C CA . HIS A 1 197 ? 23.812 106.757 31.789 1.00 78.21 ? 221 HIS A CA 1 ATOM 1475 C C . HIS A 1 197 ? 23.191 107.782 32.755 1.00 69.70 ? 221 HIS A C 1 ATOM 1476 O O . HIS A 1 197 ? 23.647 108.918 32.850 1.00 62.70 ? 221 HIS A O 1 ATOM 1477 C CB . HIS A 1 197 ? 24.180 107.397 30.440 1.00 106.23 ? 221 HIS A CB 1 ATOM 1478 C CG . HIS A 1 197 ? 24.872 106.460 29.491 1.00 122.75 ? 221 HIS A CG 1 ATOM 1479 N ND1 . HIS A 1 197 ? 26.166 106.017 29.678 1.00 129.43 ? 221 HIS A ND1 1 ATOM 1480 C CD2 . HIS A 1 197 ? 24.441 105.882 28.344 1.00 129.27 ? 221 HIS A CD2 1 ATOM 1481 C CE1 . HIS A 1 197 ? 26.500 105.208 28.688 1.00 131.50 ? 221 HIS A CE1 1 ATOM 1482 N NE2 . HIS A 1 197 ? 25.471 105.109 27.865 1.00 131.32 ? 221 HIS A NE2 1 ATOM 1483 N N . THR A 1 198 ? 22.151 107.361 33.468 1.00 67.21 ? 222 THR A N 1 ATOM 1484 C CA . THR A 1 198 ? 21.538 108.184 34.498 1.00 61.68 ? 222 THR A CA 1 ATOM 1485 C C . THR A 1 198 ? 22.529 108.337 35.667 1.00 60.89 ? 222 THR A C 1 ATOM 1486 O O . THR A 1 198 ? 23.226 107.396 36.043 1.00 58.76 ? 222 THR A O 1 ATOM 1487 C CB . THR A 1 198 ? 20.232 107.523 35.040 1.00 59.70 ? 222 THR A CB 1 ATOM 1488 O OG1 . THR A 1 198 ? 19.229 107.575 34.028 1.00 61.51 ? 222 THR A OG1 1 ATOM 1489 C CG2 . THR A 1 198 ? 19.714 108.236 36.270 1.00 61.05 ? 222 THR A CG2 1 ATOM 1490 N N . ILE A 1 199 ? 22.619 109.548 36.200 1.00 58.27 ? 223 ILE A N 1 ATOM 1491 C CA . ILE A 1 199 ? 23.441 109.800 37.360 1.00 59.08 ? 223 ILE A CA 1 ATOM 1492 C C . ILE A 1 199 ? 22.510 110.187 38.508 1.00 60.13 ? 223 ILE A C 1 ATOM 1493 O O . ILE A 1 199 ? 21.574 110.959 38.330 1.00 63.52 ? 223 ILE A O 1 ATOM 1494 C CB . ILE A 1 199 ? 24.475 110.937 37.120 1.00 58.90 ? 223 ILE A CB 1 ATOM 1495 C CG1 . ILE A 1 199 ? 25.458 110.505 36.023 1.00 59.30 ? 223 ILE A CG1 1 ATOM 1496 C CG2 . ILE A 1 199 ? 25.229 111.262 38.416 1.00 54.66 ? 223 ILE A CG2 1 ATOM 1497 C CD1 . ILE A 1 199 ? 26.306 111.633 35.439 1.00 66.55 ? 223 ILE A CD1 1 ATOM 1498 N N . GLN A 1 200 ? 22.743 109.599 39.677 1.00 62.42 ? 224 GLN A N 1 ATOM 1499 C CA . GLN A 1 200 ? 21.966 109.940 40.858 1.00 64.20 ? 224 GLN A CA 1 ATOM 1500 C C . GLN A 1 200 ? 22.901 110.589 41.872 1.00 65.58 ? 224 GLN A C 1 ATOM 1501 O O . GLN A 1 200 ? 24.012 110.107 42.120 1.00 66.19 ? 224 GLN A O 1 ATOM 1502 C CB . GLN A 1 200 ? 21.291 108.709 41.458 1.00 65.12 ? 224 GLN A CB 1 ATOM 1503 C CG . GLN A 1 200 ? 20.311 108.003 40.527 1.00 64.14 ? 224 GLN A CG 1 ATOM 1504 C CD . GLN A 1 200 ? 19.046 108.800 40.264 1.00 66.04 ? 224 GLN A CD 1 ATOM 1505 O OE1 . GLN A 1 200 ? 18.147 108.221 39.471 1.00 62.97 ? 224 GLN A OE1 1 ATOM 1506 N NE2 . GLN A 1 200 ? 18.874 109.920 40.769 1.00 65.51 ? 224 GLN A NE2 1 ATOM 1507 N N . GLN A 1 201 ? 22.441 111.695 42.440 1.00 66.31 ? 225 GLN A N 1 ATOM 1508 C CA . GLN A 1 201 ? 23.212 112.459 43.401 1.00 69.19 ? 225 GLN A CA 1 ATOM 1509 C C . GLN A 1 201 ? 22.692 112.296 44.808 1.00 66.71 ? 225 GLN A C 1 ATOM 1510 O O . GLN A 1 201 ? 21.478 112.323 45.033 1.00 62.60 ? 225 GLN A O 1 ATOM 1511 C CB . GLN A 1 201 ? 23.161 113.958 43.063 1.00 98.30 ? 225 GLN A CB 1 ATOM 1512 C CG . GLN A 1 201 ? 24.166 114.426 42.037 1.00 111.33 ? 225 GLN A CG 1 ATOM 1513 C CD . GLN A 1 201 ? 24.332 115.939 42.041 1.00 116.69 ? 225 GLN A CD 1 ATOM 1514 O OE1 . GLN A 1 201 ? 25.326 116.463 42.552 1.00 118.46 ? 225 GLN A OE1 1 ATOM 1515 N NE2 . GLN A 1 201 ? 23.352 116.649 41.482 1.00 117.35 ? 225 GLN A NE2 1 ATOM 1516 N N . LYS A 1 202 ? 23.611 112.099 45.749 1.00 66.45 ? 226 LYS A N 1 ATOM 1517 C CA . LYS A 1 202 ? 23.215 112.066 47.145 1.00 70.67 ? 226 LYS A CA 1 ATOM 1518 C C . LYS A 1 202 ? 23.505 113.458 47.714 1.00 74.84 ? 226 LYS A C 1 ATOM 1519 O O . LYS A 1 202 ? 24.404 114.167 47.240 1.00 70.60 ? 226 LYS A O 1 ATOM 1520 C CB . LYS A 1 202 ? 23.961 110.984 47.935 1.00 74.75 ? 226 LYS A CB 1 ATOM 1521 C CG . LYS A 1 202 ? 25.213 111.428 48.680 1.00 79.31 ? 226 LYS A CG 1 ATOM 1522 C CD . LYS A 1 202 ? 25.600 110.407 49.756 1.00 82.00 ? 226 LYS A CD 1 ATOM 1523 C CE . LYS A 1 202 ? 24.594 110.376 50.907 1.00 81.42 ? 226 LYS A CE 1 ATOM 1524 N NZ . LYS A 1 202 ? 24.927 109.332 51.915 1.00 80.45 ? 226 LYS A NZ 1 ATOM 1525 N N . ASN A 1 203 ? 22.725 113.845 48.719 1.00 98.10 ? 227 ASN A N 1 ATOM 1526 C CA . ASN A 1 203 ? 22.864 115.151 49.350 1.00 108.78 ? 227 ASN A CA 1 ATOM 1527 C C . ASN A 1 203 ? 24.316 115.483 49.681 1.00 109.77 ? 227 ASN A C 1 ATOM 1528 O O . ASN A 1 203 ? 25.075 114.624 50.124 1.00 111.75 ? 227 ASN A O 1 ATOM 1529 C CB . ASN A 1 203 ? 21.986 115.219 50.606 1.00 115.83 ? 227 ASN A CB 1 ATOM 1530 C CG . ASN A 1 203 ? 20.509 115.002 50.294 1.00 123.62 ? 227 ASN A CG 1 ATOM 1531 O OD1 . ASN A 1 203 ? 19.900 114.031 50.753 1.00 127.48 ? 227 ASN A OD1 1 ATOM 1532 N ND2 . ASN A 1 203 ? 19.930 115.904 49.503 1.00 126.94 ? 227 ASN A ND2 1 ATOM 1533 N N . PRO A 1 204 ? 24.725 116.736 49.432 1.00 103.38 ? 228 PRO A N 1 ATOM 1534 C CA . PRO A 1 204 ? 26.090 117.190 49.703 1.00 102.36 ? 228 PRO A CA 1 ATOM 1535 C C . PRO A 1 204 ? 26.429 117.175 51.185 1.00 104.95 ? 228 PRO A C 1 ATOM 1536 O O . PRO A 1 204 ? 25.592 117.533 52.011 1.00 106.39 ? 228 PRO A O 1 ATOM 1537 C CB . PRO A 1 204 ? 26.096 118.639 49.203 1.00 104.64 ? 228 PRO A CB 1 ATOM 1538 C CG . PRO A 1 204 ? 24.961 118.722 48.252 1.00 104.20 ? 228 PRO A CG 1 ATOM 1539 C CD . PRO A 1 204 ? 23.922 117.797 48.799 1.00 105.53 ? 228 PRO A CD 1 ATOM 1540 N N . PHE A 1 205 ? 27.648 116.746 51.508 1.00 96.15 ? 229 PHE A N 1 ATOM 1541 C CA . PHE A 1 205 ? 28.156 116.815 52.875 1.00 92.03 ? 229 PHE A CA 1 ATOM 1542 C C . PHE A 1 205 ? 28.855 118.175 53.040 1.00 93.91 ? 229 PHE A C 1 ATOM 1543 O O . PHE A 1 205 ? 29.663 118.578 52.191 1.00 95.30 ? 229 PHE A O 1 ATOM 1544 C CB . PHE A 1 205 ? 29.193 115.719 53.155 1.00 86.05 ? 229 PHE A CB 1 ATOM 1545 C CG . PHE A 1 205 ? 28.596 114.365 53.418 1.00 79.09 ? 229 PHE A CG 1 ATOM 1546 C CD1 . PHE A 1 205 ? 28.660 113.364 52.455 1.00 76.51 ? 229 PHE A CD1 1 ATOM 1547 C CD2 . PHE A 1 205 ? 27.981 114.088 54.633 1.00 76.23 ? 229 PHE A CD2 1 ATOM 1548 C CE1 . PHE A 1 205 ? 28.115 112.105 52.696 1.00 76.80 ? 229 PHE A CE1 1 ATOM 1549 C CE2 . PHE A 1 205 ? 27.432 112.832 54.884 1.00 76.59 ? 229 PHE A CE2 1 ATOM 1550 C CZ . PHE A 1 205 ? 27.502 111.836 53.913 1.00 76.90 ? 229 PHE A CZ 1 ATOM 1551 N N . THR A 1 206 ? 28.526 118.885 54.116 1.00 96.99 ? 230 THR A N 1 ATOM 1552 C CA . THR A 1 206 ? 29.187 120.155 54.405 1.00 106.95 ? 230 THR A CA 1 ATOM 1553 C C . THR A 1 206 ? 30.186 119.939 55.539 1.00 103.42 ? 230 THR A C 1 ATOM 1554 O O . THR A 1 206 ? 29.824 119.528 56.648 1.00 100.84 ? 230 THR A O 1 ATOM 1555 C CB . THR A 1 206 ? 28.196 121.270 54.808 1.00 125.10 ? 230 THR A CB 1 ATOM 1556 O OG1 . THR A 1 206 ? 27.059 121.239 53.936 1.00 132.90 ? 230 THR A OG1 1 ATOM 1557 C CG2 . THR A 1 206 ? 28.874 122.640 54.695 1.00 133.02 ? 230 THR A CG2 1 ATOM 1558 N N . LEU A 1 207 ? 31.450 120.201 55.238 1.00 112.73 ? 231 LEU A N 1 ATOM 1559 C CA . LEU A 1 207 ? 32.492 120.039 56.222 1.00 114.75 ? 231 LEU A CA 1 ATOM 1560 C C . LEU A 1 207 ? 32.751 121.328 56.977 1.00 120.59 ? 231 LEU A C 1 ATOM 1561 O O . LEU A 1 207 ? 32.955 122.384 56.368 1.00 126.85 ? 231 LEU A O 1 ATOM 1562 C CB . LEU A 1 207 ? 33.815 119.593 55.564 1.00 100.72 ? 231 LEU A CB 1 ATOM 1563 C CG . LEU A 1 207 ? 33.921 118.273 54.778 1.00 89.92 ? 231 LEU A CG 1 ATOM 1564 C CD1 . LEU A 1 207 ? 35.396 117.963 54.583 1.00 84.90 ? 231 LEU A CD1 1 ATOM 1565 C CD2 . LEU A 1 207 ? 33.237 117.114 55.492 1.00 84.69 ? 231 LEU A CD2 1 ATOM 1566 N N . LYS A 1 208 ? 32.691 121.238 58.303 1.00 131.05 ? 232 LYS A N 1 ATOM 1567 C CA . LYS A 1 208 ? 33.073 122.351 59.166 1.00 132.21 ? 232 LYS A CA 1 ATOM 1568 C C . LYS A 1 208 ? 34.250 121.842 60.026 1.00 125.79 ? 232 LYS A C 1 ATOM 1569 O O . LYS A 1 208 ? 34.049 121.230 61.082 1.00 125.52 ? 232 LYS A O 1 ATOM 1570 C CB . LYS A 1 208 ? 31.915 122.821 60.054 1.00 145.00 ? 232 LYS A CB 1 ATOM 1571 C CG . LYS A 1 208 ? 32.178 124.150 60.771 1.00 152.32 ? 232 LYS A CG 1 ATOM 1572 C CD . LYS A 1 208 ? 30.995 124.559 61.645 1.00 155.43 ? 232 LYS A CD 1 ATOM 1573 C CE . LYS A 1 208 ? 31.270 125.873 62.371 1.00 155.91 ? 232 LYS A CE 1 ATOM 1574 N NZ . LYS A 1 208 ? 30.082 126.360 63.131 1.00 155.85 ? 232 LYS A NZ 1 ATOM 1575 N N . VAL A 1 209 ? 35.474 122.076 59.546 1.00 126.53 ? 233 VAL A N 1 ATOM 1576 C CA . VAL A 1 209 ? 36.665 121.648 60.272 1.00 128.23 ? 233 VAL A CA 1 ATOM 1577 C C . VAL A 1 209 ? 36.931 122.571 61.463 1.00 130.82 ? 233 VAL A C 1 ATOM 1578 O O . VAL A 1 209 ? 36.544 123.746 61.457 1.00 129.95 ? 233 VAL A O 1 ATOM 1579 C CB . VAL A 1 209 ? 37.950 121.588 59.348 1.00 124.27 ? 233 VAL A CB 1 ATOM 1580 C CG1 . VAL A 1 209 ? 37.626 120.880 58.046 1.00 120.20 ? 233 VAL A CG1 1 ATOM 1581 C CG2 . VAL A 1 209 ? 38.519 122.979 59.077 1.00 120.44 ? 233 VAL A CG2 1 ATOM 1582 N N . LEU A 1 210 ? 37.553 122.019 62.500 1.00 140.74 ? 234 LEU A N 1 ATOM 1583 C CA . LEU A 1 210 ? 37.900 122.797 63.683 1.00 152.01 ? 234 LEU A CA 1 ATOM 1584 C C . LEU A 1 210 ? 39.409 122.824 63.914 1.00 159.14 ? 234 LEU A C 1 ATOM 1585 O O . LEU A 1 210 ? 40.050 121.776 64.050 1.00 171.07 ? 234 LEU A O 1 ATOM 1586 C CB . LEU A 1 210 ? 37.195 122.248 64.937 1.00 120.92 ? 234 LEU A CB 1 ATOM 1587 C CG . LEU A 1 210 ? 35.877 122.919 65.358 1.00 106.11 ? 234 LEU A CG 1 ATOM 1588 C CD1 . LEU A 1 210 ? 35.162 122.046 66.382 1.00 98.00 ? 234 LEU A CD1 1 ATOM 1589 C CD2 . LEU A 1 210 ? 36.135 124.322 65.922 1.00 98.12 ? 234 LEU A CD2 1 ATOM 1590 N N . THR A 1 211 ? 39.968 124.033 63.927 1.00 162.95 ? 235 THR A N 1 ATOM 1591 C CA . THR A 1 211 ? 41.392 124.215 64.202 1.00 162.79 ? 235 THR A CA 1 ATOM 1592 C C . THR A 1 211 ? 41.631 124.062 65.715 1.00 162.12 ? 235 THR A C 1 ATOM 1593 O O . THR A 1 211 ? 41.052 124.784 66.539 1.00 158.63 ? 235 THR A O 1 ATOM 1594 C CB . THR A 1 211 ? 41.923 125.589 63.663 1.00 152.71 ? 235 THR A CB 1 ATOM 1595 O OG1 . THR A 1 211 ? 43.242 125.826 64.171 1.00 150.99 ? 235 THR A OG1 1 ATOM 1596 C CG2 . THR A 1 211 ? 40.996 126.752 64.034 1.00 151.07 ? 235 THR A CG2 1 ATOM 1597 N N . THR A 1 212 ? 42.477 123.092 66.064 1.00 146.37 ? 236 THR A N 1 ATOM 1598 C CA . THR A 1 212 ? 42.766 122.780 67.462 1.00 151.31 ? 236 THR A CA 1 ATOM 1599 C C . THR A 1 212 ? 44.208 123.097 67.874 1.00 150.14 ? 236 THR A C 1 ATOM 1600 O O . THR A 1 212 ? 44.676 122.671 68.932 1.00 147.48 ? 236 THR A O 1 ATOM 1601 C CB . THR A 1 212 ? 42.418 121.277 67.769 1.00 158.81 ? 236 THR A CB 1 ATOM 1602 O OG1 . THR A 1 212 ? 42.642 121.004 69.160 1.00 163.57 ? 236 THR A OG1 1 ATOM 1603 C CG2 . THR A 1 212 ? 43.252 120.321 66.911 1.00 163.55 ? 236 THR A CG2 1 ATOM 1604 N N . ARG A 1 213 ? 44.889 123.875 67.033 1.00 166.38 ? 237 ARG A N 1 ATOM 1605 C CA . ARG A 1 213 ? 46.275 124.304 67.254 1.00 167.01 ? 237 ARG A CA 1 ATOM 1606 C C . ARG A 1 213 ? 47.183 123.135 67.649 1.00 161.67 ? 237 ARG A C 1 ATOM 1607 O O . ARG A 1 213 ? 47.636 123.020 68.792 1.00 165.28 ? 237 ARG A O 1 ATOM 1608 C CB . ARG A 1 213 ? 46.323 125.447 68.295 1.00 165.89 ? 237 ARG A CB 1 ATOM 1609 C CG . ARG A 1 213 ? 47.704 126.080 68.477 1.00 169.39 ? 237 ARG A CG 1 ATOM 1610 C CD . ARG A 1 213 ? 47.613 127.553 68.856 1.00 170.74 ? 237 ARG A CD 1 ATOM 1611 N NE . ARG A 1 213 ? 47.338 128.400 67.696 1.00 171.21 ? 237 ARG A NE 1 ATOM 1612 C CZ . ARG A 1 213 ? 48.256 128.816 66.824 1.00 171.45 ? 237 ARG A CZ 1 ATOM 1613 N NH1 . ARG A 1 213 ? 49.529 128.471 66.967 1.00 171.53 ? 237 ARG A NH1 1 ATOM 1614 N NH2 . ARG A 1 213 ? 47.897 129.585 65.801 1.00 171.74 ? 237 ARG A NH2 1 ATOM 1615 N N . GLY A 1 214 ? 47.435 122.270 66.668 1.00 139.16 ? 238 GLY A N 1 ATOM 1616 C CA . GLY A 1 214 ? 48.271 121.104 66.875 1.00 133.87 ? 238 GLY A CA 1 ATOM 1617 C C . GLY A 1 214 ? 48.469 120.266 65.626 1.00 134.50 ? 238 GLY A C 1 ATOM 1618 O O . GLY A 1 214 ? 47.502 119.818 65.002 1.00 128.87 ? 238 GLY A O 1 ATOM 1619 N N . VAL A 1 215 ? 49.734 120.077 65.254 1.00 154.18 ? 239 VAL A N 1 ATOM 1620 C CA . VAL A 1 215 ? 50.093 119.238 64.114 1.00 162.72 ? 239 VAL A CA 1 ATOM 1621 C C . VAL A 1 215 ? 50.245 117.783 64.622 1.00 168.33 ? 239 VAL A C 1 ATOM 1622 O O . VAL A 1 215 ? 50.537 116.873 63.837 1.00 177.85 ? 239 VAL A O 1 ATOM 1623 C CB . VAL A 1 215 ? 51.448 119.703 63.468 1.00 149.30 ? 239 VAL A CB 1 ATOM 1624 C CG1 . VAL A 1 215 ? 51.571 119.153 62.046 1.00 138.96 ? 239 VAL A CG1 1 ATOM 1625 C CG2 . VAL A 1 215 ? 51.545 121.233 63.460 1.00 139.11 ? 239 VAL A CG2 1 ATOM 1626 N N . ALA A 1 216 ? 50.008 117.593 65.930 1.00 175.11 ? 240 ALA A N 1 ATOM 1627 C CA . ALA A 1 216 ? 50.158 116.313 66.626 1.00 170.12 ? 240 ALA A CA 1 ATOM 1628 C C . ALA A 1 216 ? 50.320 115.222 65.562 1.00 168.31 ? 240 ALA A C 1 ATOM 1629 O O . ALA A 1 216 ? 49.374 114.856 64.861 1.00 176.33 ? 240 ALA A O 1 ATOM 1630 C CB . ALA A 1 216 ? 48.966 116.086 67.594 1.00 117.21 ? 240 ALA A CB 1 ATOM 1631 N N . GLU A 1 217 ? 51.566 114.746 65.426 1.00 145.47 ? 241 GLU A N 1 ATOM 1632 C CA . GLU A 1 217 ? 51.929 113.726 64.426 1.00 137.73 ? 241 GLU A CA 1 ATOM 1633 C C . GLU A 1 217 ? 51.633 112.389 65.092 1.00 138.15 ? 241 GLU A C 1 ATOM 1634 O O . GLU A 1 217 ? 52.129 112.102 66.185 1.00 142.01 ? 241 GLU A O 1 ATOM 1635 C CB . GLU A 1 217 ? 53.403 113.850 64.010 1.00 122.51 ? 241 GLU A CB 1 ATOM 1636 C CG . GLU A 1 217 ? 53.739 115.163 63.302 1.00 110.29 ? 241 GLU A CG 1 ATOM 1637 C CD . GLU A 1 217 ? 55.232 115.354 63.049 1.00 105.86 ? 241 GLU A CD 1 ATOM 1638 O OE1 . GLU A 1 217 ? 55.623 116.485 62.687 1.00 105.00 ? 241 GLU A OE1 1 ATOM 1639 O OE2 . GLU A 1 217 ? 56.014 114.388 63.204 1.00 104.01 ? 241 GLU A OE2 1 ATOM 1640 N N . ARG A 1 218 ? 50.835 111.571 64.411 1.00 135.73 ? 242 ARG A N 1 ATOM 1641 C CA . ARG A 1 218 ? 50.314 110.330 64.983 1.00 136.22 ? 242 ARG A CA 1 ATOM 1642 C C . ARG A 1 218 ? 50.700 109.085 64.216 1.00 134.19 ? 242 ARG A C 1 ATOM 1643 O O . ARG A 1 218 ? 51.108 109.166 63.058 1.00 133.20 ? 242 ARG A O 1 ATOM 1644 C CB . ARG A 1 218 ? 48.773 110.434 65.014 1.00 127.43 ? 242 ARG A CB 1 ATOM 1645 C CG . ARG A 1 218 ? 48.085 109.856 66.244 1.00 130.74 ? 242 ARG A CG 1 ATOM 1646 C CD . ARG A 1 218 ? 46.622 110.292 66.289 1.00 132.63 ? 242 ARG A CD 1 ATOM 1647 N NE . ARG A 1 218 ? 45.996 109.950 67.569 1.00 133.80 ? 242 ARG A NE 1 ATOM 1648 C CZ . ARG A 1 218 ? 44.957 110.591 68.108 1.00 134.36 ? 242 ARG A CZ 1 ATOM 1649 N NH1 . ARG A 1 218 ? 44.399 111.628 67.488 1.00 134.67 ? 242 ARG A NH1 1 ATOM 1650 N NH2 . ARG A 1 218 ? 44.476 110.194 69.282 1.00 134.63 ? 242 ARG A NH2 1 ATOM 1651 N N . THR A 1 219 ? 50.576 107.934 64.880 1.00 131.39 ? 243 THR A N 1 ATOM 1652 C CA . THR A 1 219 ? 50.842 106.636 64.257 1.00 121.68 ? 243 THR A CA 1 ATOM 1653 C C . THR A 1 219 ? 49.714 106.323 63.256 1.00 116.51 ? 243 THR A C 1 ATOM 1654 O O . THR A 1 219 ? 48.575 106.752 63.445 1.00 129.66 ? 243 THR A O 1 ATOM 1655 C CB . THR A 1 219 ? 50.935 105.504 65.321 1.00 112.23 ? 243 THR A CB 1 ATOM 1656 O OG1 . THR A 1 219 ? 49.783 105.532 66.175 1.00 102.69 ? 243 THR A OG1 1 ATOM 1657 C CG2 . THR A 1 219 ? 52.190 105.678 66.166 1.00 102.24 ? 243 THR A CG2 1 ATOM 1658 N N . PRO A 1 220 ? 50.021 105.577 62.175 1.00 98.41 ? 244 PRO A N 1 ATOM 1659 C CA . PRO A 1 220 ? 48.999 105.245 61.174 1.00 92.14 ? 244 PRO A CA 1 ATOM 1660 C C . PRO A 1 220 ? 47.967 104.239 61.661 1.00 93.23 ? 244 PRO A C 1 ATOM 1661 O O . PRO A 1 220 ? 48.229 103.481 62.591 1.00 96.71 ? 244 PRO A O 1 ATOM 1662 C CB . PRO A 1 220 ? 49.815 104.692 60.007 1.00 75.46 ? 244 PRO A CB 1 ATOM 1663 C CG . PRO A 1 220 ? 50.978 104.061 60.665 1.00 71.61 ? 244 PRO A CG 1 ATOM 1664 C CD . PRO A 1 220 ? 51.315 104.949 61.844 1.00 80.27 ? 244 PRO A CD 1 ATOM 1665 N N . SER A 1 221 ? 46.800 104.234 61.026 1.00 88.22 ? 245 SER A N 1 ATOM 1666 C CA . SER A 1 221 ? 45.738 103.292 61.373 1.00 86.40 ? 245 SER A CA 1 ATOM 1667 C C . SER A 1 221 ? 45.040 102.795 60.096 1.00 80.74 ? 245 SER A C 1 ATOM 1668 O O . SER A 1 221 ? 45.222 103.371 59.022 1.00 78.25 ? 245 SER A O 1 ATOM 1669 C CB . SER A 1 221 ? 44.731 103.955 62.321 1.00 100.20 ? 245 SER A CB 1 ATOM 1670 O OG . SER A 1 221 ? 43.758 103.027 62.767 1.00 104.03 ? 245 SER A OG 1 ATOM 1671 N N . PHE A 1 222 ? 44.268 101.716 60.201 1.00 78.36 ? 246 PHE A N 1 ATOM 1672 C CA . PHE A 1 222 ? 43.573 101.201 59.026 1.00 71.66 ? 246 PHE A CA 1 ATOM 1673 C C . PHE A 1 222 ? 42.125 101.657 58.941 1.00 68.40 ? 246 PHE A C 1 ATOM 1674 O O . PHE A 1 222 ? 41.283 101.307 59.773 1.00 67.83 ? 246 PHE A O 1 ATOM 1675 C CB . PHE A 1 222 ? 43.695 99.678 58.937 1.00 74.35 ? 246 PHE A CB 1 ATOM 1676 C CG . PHE A 1 222 ? 44.998 99.225 58.341 1.00 74.71 ? 246 PHE A CG 1 ATOM 1677 C CD1 . PHE A 1 222 ? 45.820 98.337 59.021 1.00 75.39 ? 246 PHE A CD1 1 ATOM 1678 C CD2 . PHE A 1 222 ? 45.414 99.706 57.096 1.00 74.62 ? 246 PHE A CD2 1 ATOM 1679 C CE1 . PHE A 1 222 ? 47.033 97.927 58.475 1.00 75.59 ? 246 PHE A CE1 1 ATOM 1680 C CE2 . PHE A 1 222 ? 46.626 99.301 56.541 1.00 74.42 ? 246 PHE A CE2 1 ATOM 1681 C CZ . PHE A 1 222 ? 47.436 98.414 57.231 1.00 74.94 ? 246 PHE A CZ 1 ATOM 1682 N N . MET A 1 223 ? 41.849 102.452 57.909 1.00 58.26 ? 247 MET A N 1 ATOM 1683 C CA . MET A 1 223 ? 40.530 103.017 57.724 1.00 64.81 ? 247 MET A CA 1 ATOM 1684 C C . MET A 1 223 ? 39.561 102.017 57.128 1.00 69.92 ? 247 MET A C 1 ATOM 1685 O O . MET A 1 223 ? 38.637 101.592 57.818 1.00 62.65 ? 247 MET A O 1 ATOM 1686 C CB . MET A 1 223 ? 40.609 104.287 56.868 1.00 79.38 ? 247 MET A CB 1 ATOM 1687 C CG . MET A 1 223 ? 41.606 105.314 57.390 1.00 87.35 ? 247 MET A CG 1 ATOM 1688 S SD . MET A 1 223 ? 41.322 106.986 56.761 1.00 91.56 ? 247 MET A SD 1 ATOM 1689 C CE . MET A 1 223 ? 39.885 107.465 57.729 1.00 92.70 ? 247 MET A CE 1 ATOM 1690 N N . TYR A 1 224 ? 39.769 101.616 55.874 1.00 107.02 ? 248 TYR A N 1 ATOM 1691 C CA . TYR A 1 224 ? 38.835 100.681 55.267 1.00 116.80 ? 248 TYR A CA 1 ATOM 1692 C C . TYR A 1 224 ? 38.945 99.250 55.750 1.00 117.05 ? 248 TYR A C 1 ATOM 1693 O O . TYR A 1 224 ? 38.065 98.779 56.488 1.00 146.25 ? 248 TYR A O 1 ATOM 1694 C CB . TYR A 1 224 ? 38.893 100.688 53.726 1.00 87.80 ? 248 TYR A CB 1 ATOM 1695 C CG . TYR A 1 224 ? 38.280 99.436 53.106 1.00 65.79 ? 248 TYR A CG 1 ATOM 1696 C CD1 . TYR A 1 224 ? 37.001 99.006 53.473 1.00 54.85 ? 248 TYR A CD1 1 ATOM 1697 C CD2 . TYR A 1 224 ? 38.987 98.677 52.179 1.00 54.77 ? 248 TYR A CD2 1 ATOM 1698 C CE1 . TYR A 1 224 ? 36.445 97.856 52.938 1.00 51.39 ? 248 TYR A CE1 1 ATOM 1699 C CE2 . TYR A 1 224 ? 38.434 97.521 51.636 1.00 52.95 ? 248 TYR A CE2 1 ATOM 1700 C CZ . TYR A 1 224 ? 37.160 97.120 52.023 1.00 52.36 ? 248 TYR A CZ 1 ATOM 1701 O OH . TYR A 1 224 ? 36.595 95.985 51.490 1.00 54.77 ? 248 TYR A OH 1 ATOM 1702 N N . PRO A 1 225 ? 40.025 98.538 55.374 1.00 75.70 ? 249 PRO A N 1 ATOM 1703 C CA . PRO A 1 225 ? 40.008 97.160 55.885 1.00 63.38 ? 249 PRO A CA 1 ATOM 1704 C C . PRO A 1 225 ? 40.163 97.239 57.391 1.00 59.74 ? 249 PRO A C 1 ATOM 1705 O O . PRO A 1 225 ? 41.203 97.648 57.889 1.00 54.78 ? 249 PRO A O 1 ATOM 1706 C CB . PRO A 1 225 ? 41.167 96.493 55.148 1.00 44.99 ? 249 PRO A CB 1 ATOM 1707 C CG . PRO A 1 225 ? 41.777 97.564 54.267 1.00 41.67 ? 249 PRO A CG 1 ATOM 1708 C CD . PRO A 1 225 ? 41.335 98.888 54.794 1.00 54.09 ? 249 PRO A CD 1 ATOM 1709 N N . GLN A 1 226 ? 39.108 96.866 58.109 1.00 61.31 ? 250 GLN A N 1 ATOM 1710 C CA . GLN A 1 226 ? 39.097 97.025 59.553 1.00 64.13 ? 250 GLN A CA 1 ATOM 1711 C C . GLN A 1 226 ? 40.094 96.153 60.268 1.00 66.85 ? 250 GLN A C 1 ATOM 1712 O O . GLN A 1 226 ? 40.147 94.947 60.030 1.00 63.01 ? 250 GLN A O 1 ATOM 1713 C CB . GLN A 1 226 ? 37.695 96.745 60.126 1.00 73.42 ? 250 GLN A CB 1 ATOM 1714 C CG . GLN A 1 226 ? 36.546 97.448 59.428 1.00 76.82 ? 250 GLN A CG 1 ATOM 1715 C CD . GLN A 1 226 ? 35.387 97.734 60.373 1.00 79.03 ? 250 GLN A CD 1 ATOM 1716 O OE1 . GLN A 1 226 ? 35.393 98.738 61.095 1.00 79.89 ? 250 GLN A OE1 1 ATOM 1717 N NE2 . GLN A 1 226 ? 34.395 96.850 60.381 1.00 78.86 ? 250 GLN A NE2 1 ATOM 1718 N N . GLY A 1 227 ? 40.906 96.794 61.108 1.00 81.14 ? 251 GLY A N 1 ATOM 1719 C CA . GLY A 1 227 ? 41.824 96.077 61.954 1.00 82.92 ? 251 GLY A CA 1 ATOM 1720 C C . GLY A 1 227 ? 43.012 95.389 61.346 1.00 80.83 ? 251 GLY A C 1 ATOM 1721 O O . GLY A 1 227 ? 43.676 95.935 60.470 1.00 86.09 ? 251 GLY A O 1 ATOM 1722 N N . THR A 1 228 ? 43.223 94.154 61.784 1.00 63.90 ? 252 THR A N 1 ATOM 1723 C CA . THR A 1 228 ? 44.412 93.390 61.459 1.00 57.23 ? 252 THR A CA 1 ATOM 1724 C C . THR A 1 228 ? 44.408 92.607 60.170 1.00 54.07 ? 252 THR A C 1 ATOM 1725 O O . THR A 1 228 ? 45.321 92.735 59.362 1.00 50.84 ? 252 THR A O 1 ATOM 1726 C CB . THR A 1 228 ? 44.742 92.442 62.691 1.00 57.30 ? 252 THR A CB 1 ATOM 1727 O OG1 . THR A 1 228 ? 45.567 93.152 63.628 1.00 57.13 ? 252 THR A OG1 1 ATOM 1728 C CG2 . THR A 1 228 ? 45.441 91.163 62.268 1.00 57.28 ? 252 THR A CG2 1 ATOM 1729 N N . ALA A 1 229 ? 43.358 91.824 59.963 1.00 54.86 ? 253 ALA A N 1 ATOM 1730 C CA . ALA A 1 229 ? 43.275 90.959 58.802 1.00 55.52 ? 253 ALA A CA 1 ATOM 1731 C C . ALA A 1 229 ? 41.923 91.027 58.090 1.00 56.97 ? 253 ALA A C 1 ATOM 1732 O O . ALA A 1 229 ? 40.997 91.698 58.547 1.00 58.88 ? 253 ALA A O 1 ATOM 1733 C CB . ALA A 1 229 ? 43.538 89.511 59.257 1.00 48.17 ? 253 ALA A CB 1 ATOM 1734 N N . SER A 1 230 ? 41.842 90.346 56.945 1.00 55.89 ? 254 SER A N 1 ATOM 1735 C CA . SER A 1 230 ? 40.605 90.222 56.183 1.00 56.31 ? 254 SER A CA 1 ATOM 1736 C C . SER A 1 230 ? 40.742 89.081 55.185 1.00 59.63 ? 254 SER A C 1 ATOM 1737 O O . SER A 1 230 ? 41.842 88.753 54.745 1.00 58.73 ? 254 SER A O 1 ATOM 1738 C CB . SER A 1 230 ? 40.229 91.520 55.455 1.00 52.98 ? 254 SER A CB 1 ATOM 1739 O OG . SER A 1 230 ? 41.244 91.953 54.561 1.00 52.41 ? 254 SER A OG 1 ATOM 1740 N N . SER A 1 231 ? 39.617 88.464 54.849 1.00 64.08 ? 255 SER A N 1 ATOM 1741 C CA . SER A 1 231 ? 39.604 87.375 53.909 1.00 64.30 ? 255 SER A CA 1 ATOM 1742 C C . SER A 1 231 ? 38.849 87.809 52.653 1.00 60.50 ? 255 SER A C 1 ATOM 1743 O O . SER A 1 231 ? 38.050 88.741 52.701 1.00 61.40 ? 255 SER A O 1 ATOM 1744 C CB . SER A 1 231 ? 38.921 86.161 54.528 1.00 70.00 ? 255 SER A CB 1 ATOM 1745 O OG . SER A 1 231 ? 39.031 85.031 53.674 1.00 78.45 ? 255 SER A OG 1 ATOM 1746 N N . GLN A 1 232 ? 39.124 87.135 51.531 1.00 47.00 ? 256 GLN A N 1 ATOM 1747 C CA . GLN A 1 232 ? 38.462 87.427 50.279 1.00 40.55 ? 256 GLN A CA 1 ATOM 1748 C C . GLN A 1 232 ? 38.391 86.202 49.421 1.00 39.87 ? 256 GLN A C 1 ATOM 1749 O O . GLN A 1 232 ? 39.387 85.521 49.213 1.00 37.50 ? 256 GLN A O 1 ATOM 1750 C CB . GLN A 1 232 ? 39.200 88.523 49.482 1.00 49.84 ? 256 GLN A CB 1 ATOM 1751 C CG . GLN A 1 232 ? 38.801 89.943 49.817 1.00 54.60 ? 256 GLN A CG 1 ATOM 1752 C CD . GLN A 1 232 ? 39.398 90.958 48.861 1.00 58.47 ? 256 GLN A CD 1 ATOM 1753 O OE1 . GLN A 1 232 ? 39.368 90.766 47.648 1.00 58.84 ? 256 GLN A OE1 1 ATOM 1754 N NE2 . GLN A 1 232 ? 39.929 92.059 49.407 1.00 59.63 ? 256 GLN A NE2 1 ATOM 1755 N N . MET A 1 233 ? 37.195 85.901 48.945 1.00 55.79 ? 257 MET A N 1 ATOM 1756 C CA . MET A 1 233 ? 37.028 84.825 47.992 1.00 62.45 ? 257 MET A CA 1 ATOM 1757 C C . MET A 1 233 ? 36.950 85.518 46.612 1.00 65.69 ? 257 MET A C 1 ATOM 1758 O O . MET A 1 233 ? 36.478 86.657 46.511 1.00 69.61 ? 257 MET A O 1 ATOM 1759 C CB . MET A 1 233 ? 35.764 84.033 48.287 1.00 62.78 ? 257 MET A CB 1 ATOM 1760 C CG . MET A 1 233 ? 35.605 82.796 47.438 1.00 65.83 ? 257 MET A CG 1 ATOM 1761 S SD . MET A 1 233 ? 35.068 83.232 45.777 1.00 70.06 ? 257 MET A SD 1 ATOM 1762 C CE . MET A 1 233 ? 33.383 83.797 46.109 1.00 69.16 ? 257 MET A CE 1 ATOM 1763 N N . VAL A 1 234 ? 37.442 84.842 45.570 1.00 62.75 ? 258 VAL A N 1 ATOM 1764 C CA . VAL A 1 234 ? 37.442 85.396 44.207 1.00 60.00 ? 258 VAL A CA 1 ATOM 1765 C C . VAL A 1 234 ? 37.332 84.295 43.148 1.00 56.92 ? 258 VAL A C 1 ATOM 1766 O O . VAL A 1 234 ? 37.933 83.216 43.286 1.00 56.87 ? 258 VAL A O 1 ATOM 1767 C CB . VAL A 1 234 ? 38.693 86.299 43.971 1.00 56.73 ? 258 VAL A CB 1 ATOM 1768 C CG1 . VAL A 1 234 ? 39.884 85.496 43.482 1.00 56.00 ? 258 VAL A CG1 1 ATOM 1769 C CG2 . VAL A 1 234 ? 38.350 87.403 43.002 1.00 58.14 ? 258 VAL A CG2 1 ATOM 1770 N N . LEU A 1 235 ? 36.548 84.561 42.103 1.00 50.49 ? 259 LEU A N 1 ATOM 1771 C CA . LEU A 1 235 ? 36.304 83.544 41.086 1.00 50.60 ? 259 LEU A CA 1 ATOM 1772 C C . LEU A 1 235 ? 37.394 83.469 40.031 1.00 51.30 ? 259 LEU A C 1 ATOM 1773 O O . LEU A 1 235 ? 37.921 84.490 39.588 1.00 46.39 ? 259 LEU A O 1 ATOM 1774 C CB . LEU A 1 235 ? 34.943 83.770 40.391 1.00 54.18 ? 259 LEU A CB 1 ATOM 1775 C CG . LEU A 1 235 ? 33.644 83.555 41.189 1.00 56.82 ? 259 LEU A CG 1 ATOM 1776 C CD1 . LEU A 1 235 ? 32.453 83.852 40.311 1.00 57.48 ? 259 LEU A CD1 1 ATOM 1777 C CD2 . LEU A 1 235 ? 33.557 82.135 41.724 1.00 58.63 ? 259 LEU A CD2 1 ATOM 1778 N N . ARG A 1 236 ? 37.745 82.245 39.655 1.00 61.46 ? 260 ARG A N 1 ATOM 1779 C CA . ARG A 1 236 ? 38.726 82.017 38.615 1.00 64.86 ? 260 ARG A CA 1 ATOM 1780 C C . ARG A 1 236 ? 38.354 82.838 37.387 1.00 67.82 ? 260 ARG A C 1 ATOM 1781 O O . ARG A 1 236 ? 37.213 82.777 36.922 1.00 71.94 ? 260 ARG A O 1 ATOM 1782 C CB . ARG A 1 236 ? 38.734 80.543 38.232 1.00 63.14 ? 260 ARG A CB 1 ATOM 1783 C CG . ARG A 1 236 ? 39.640 80.215 37.075 1.00 62.71 ? 260 ARG A CG 1 ATOM 1784 C CD . ARG A 1 236 ? 39.648 78.732 36.789 1.00 64.63 ? 260 ARG A CD 1 ATOM 1785 N NE . ARG A 1 236 ? 40.728 78.392 35.875 1.00 68.17 ? 260 ARG A NE 1 ATOM 1786 C CZ . ARG A 1 236 ? 40.606 78.319 34.552 1.00 70.36 ? 260 ARG A CZ 1 ATOM 1787 N NH1 . ARG A 1 236 ? 39.434 78.555 33.971 1.00 69.39 ? 260 ARG A NH1 1 ATOM 1788 N NH2 . ARG A 1 236 ? 41.668 78.014 33.808 1.00 72.53 ? 260 ARG A NH2 1 ATOM 1789 N N . GLY A 1 237 ? 39.312 83.613 36.877 1.00 65.37 ? 261 GLY A N 1 ATOM 1790 C CA . GLY A 1 237 ? 39.084 84.413 35.682 1.00 65.03 ? 261 GLY A CA 1 ATOM 1791 C C . GLY A 1 237 ? 38.713 85.863 35.941 1.00 63.88 ? 261 GLY A C 1 ATOM 1792 O O . GLY A 1 237 ? 38.921 86.725 35.082 1.00 66.80 ? 261 GLY A O 1 ATOM 1793 N N . MET A 1 238 ? 38.168 86.135 37.127 1.00 54.66 ? 262 MET A N 1 ATOM 1794 C CA . MET A 1 238 ? 37.762 87.485 37.494 1.00 52.06 ? 262 MET A CA 1 ATOM 1795 C C . MET A 1 238 ? 38.953 88.274 37.997 1.00 51.18 ? 262 MET A C 1 ATOM 1796 O O . MET A 1 238 ? 40.058 87.746 38.073 1.00 46.61 ? 262 MET A O 1 ATOM 1797 C CB . MET A 1 238 ? 36.670 87.445 38.574 1.00 60.25 ? 262 MET A CB 1 ATOM 1798 C CG . MET A 1 238 ? 35.396 86.706 38.162 1.00 64.88 ? 262 MET A CG 1 ATOM 1799 S SD . MET A 1 238 ? 34.585 87.388 36.694 1.00 71.08 ? 262 MET A SD 1 ATOM 1800 C CE . MET A 1 238 ? 33.806 88.878 37.390 1.00 70.53 ? 262 MET A CE 1 ATOM 1801 N N . ASP A 1 239 ? 38.730 89.546 38.312 1.00 56.07 ? 263 ASP A N 1 ATOM 1802 C CA . ASP A 1 239 ? 39.785 90.395 38.857 1.00 57.16 ? 263 ASP A CA 1 ATOM 1803 C C . ASP A 1 239 ? 39.797 90.310 40.386 1.00 54.61 ? 263 ASP A C 1 ATOM 1804 O O . ASP A 1 239 ? 38.772 90.027 41.015 1.00 53.72 ? 263 ASP A O 1 ATOM 1805 C CB . ASP A 1 239 ? 39.577 91.862 38.450 1.00 72.18 ? 263 ASP A CB 1 ATOM 1806 C CG . ASP A 1 239 ? 39.791 92.101 36.964 1.00 79.18 ? 263 ASP A CG 1 ATOM 1807 O OD1 . ASP A 1 239 ? 40.017 91.119 36.205 1.00 82.46 ? 263 ASP A OD1 1 ATOM 1808 O OD2 . ASP A 1 239 ? 39.727 93.286 36.557 1.00 82.33 ? 263 ASP A OD2 1 ATOM 1809 N N . LEU A 1 240 ? 40.969 90.558 40.974 1.00 52.11 ? 264 LEU A N 1 ATOM 1810 C CA . LEU A 1 240 ? 41.116 90.559 42.418 1.00 48.92 ? 264 LEU A CA 1 ATOM 1811 C C . LEU A 1 240 ? 41.537 91.955 42.832 1.00 48.75 ? 264 LEU A C 1 ATOM 1812 O O . LEU A 1 240 ? 42.545 92.471 42.356 1.00 49.29 ? 264 LEU A O 1 ATOM 1813 C CB . LEU A 1 240 ? 42.150 89.512 42.838 1.00 53.75 ? 264 LEU A CB 1 ATOM 1814 C CG . LEU A 1 240 ? 42.614 89.196 44.292 1.00 53.19 ? 264 LEU A CG 1 ATOM 1815 C CD1 . LEU A 1 240 ? 43.950 89.847 44.552 1.00 50.79 ? 264 LEU A CD1 1 ATOM 1816 C CD2 . LEU A 1 240 ? 41.586 89.562 45.356 1.00 51.91 ? 264 LEU A CD2 1 ATOM 1817 N N . LEU A 1 241 ? 40.752 92.568 43.712 1.00 54.46 ? 265 LEU A N 1 ATOM 1818 C CA . LEU A 1 241 ? 41.033 93.925 44.165 1.00 59.26 ? 265 LEU A CA 1 ATOM 1819 C C . LEU A 1 241 ? 41.347 93.977 45.650 1.00 60.03 ? 265 LEU A C 1 ATOM 1820 O O . LEU A 1 241 ? 40.518 93.625 46.483 1.00 62.66 ? 265 LEU A O 1 ATOM 1821 C CB . LEU A 1 241 ? 39.841 94.840 43.860 1.00 59.44 ? 265 LEU A CB 1 ATOM 1822 C CG . LEU A 1 241 ? 40.100 96.251 43.280 1.00 61.12 ? 265 LEU A CG 1 ATOM 1823 C CD1 . LEU A 1 241 ? 40.642 97.215 44.321 1.00 59.65 ? 265 LEU A CD1 1 ATOM 1824 C CD2 . LEU A 1 241 ? 41.053 96.158 42.083 1.00 61.46 ? 265 LEU A CD2 1 ATOM 1825 N N . LEU A 1 242 ? 42.557 94.412 45.970 1.00 54.22 ? 266 LEU A N 1 ATOM 1826 C CA . LEU A 1 242 ? 42.992 94.529 47.347 1.00 53.62 ? 266 LEU A CA 1 ATOM 1827 C C . LEU A 1 242 ? 43.148 96.007 47.668 1.00 54.61 ? 266 LEU A C 1 ATOM 1828 O O . LEU A 1 242 ? 43.706 96.760 46.867 1.00 53.22 ? 266 LEU A O 1 ATOM 1829 C CB . LEU A 1 242 ? 44.334 93.824 47.539 1.00 56.87 ? 266 LEU A CB 1 ATOM 1830 C CG . LEU A 1 242 ? 44.467 92.413 46.968 1.00 58.13 ? 266 LEU A CG 1 ATOM 1831 C CD1 . LEU A 1 242 ? 45.922 92.152 46.628 1.00 59.49 ? 266 LEU A CD1 1 ATOM 1832 C CD2 . LEU A 1 242 ? 43.925 91.382 47.951 1.00 58.35 ? 266 LEU A CD2 1 ATOM 1833 N N . GLU A 1 243 ? 42.670 96.414 48.842 1.00 54.98 ? 267 GLU A N 1 ATOM 1834 C CA . GLU A 1 243 ? 42.739 97.814 49.237 1.00 56.09 ? 267 GLU A CA 1 ATOM 1835 C C . GLU A 1 243 ? 43.267 97.991 50.644 1.00 55.50 ? 267 GLU A C 1 ATOM 1836 O O . GLU A 1 243 ? 43.088 97.126 51.499 1.00 52.42 ? 267 GLU A O 1 ATOM 1837 C CB . GLU A 1 243 ? 41.344 98.453 49.176 1.00 77.99 ? 267 GLU A CB 1 ATOM 1838 C CG . GLU A 1 243 ? 40.815 98.713 47.775 1.00 87.67 ? 267 GLU A CG 1 ATOM 1839 C CD . GLU A 1 243 ? 39.455 99.397 47.781 1.00 92.75 ? 267 GLU A CD 1 ATOM 1840 O OE1 . GLU A 1 243 ? 38.475 98.793 48.284 1.00 94.11 ? 267 GLU A OE1 1 ATOM 1841 O OE2 . GLU A 1 243 ? 39.370 100.542 47.283 1.00 94.33 ? 267 GLU A OE2 1 ATOM 1842 N N . CYS A 1 244 ? 43.923 99.122 50.867 1.00 56.88 ? 268 CYS A N 1 ATOM 1843 C CA . CYS A 1 244 ? 44.416 99.486 52.176 1.00 56.37 ? 268 CYS A CA 1 ATOM 1844 C C . CYS A 1 244 ? 44.361 100.999 52.289 1.00 55.57 ? 268 CYS A C 1 ATOM 1845 O O . CYS A 1 244 ? 45.099 101.700 51.595 1.00 55.18 ? 268 CYS A O 1 ATOM 1846 C CB . CYS A 1 244 ? 45.861 99.008 52.398 1.00 66.85 ? 268 CYS A CB 1 ATOM 1847 S SG . CYS A 1 244 ? 46.035 97.220 52.699 1.00 73.03 ? 268 CYS A SG 1 ATOM 1848 N N . ILE A 1 245 ? 43.481 101.501 53.149 1.00 59.43 ? 269 ILE A N 1 ATOM 1849 C CA . ILE A 1 245 ? 43.387 102.944 53.358 1.00 63.39 ? 269 ILE A CA 1 ATOM 1850 C C . ILE A 1 245 ? 43.835 103.257 54.787 1.00 66.43 ? 269 ILE A C 1 ATOM 1851 O O . ILE A 1 245 ? 43.269 102.738 55.760 1.00 63.07 ? 269 ILE A O 1 ATOM 1852 C CB . ILE A 1 245 ? 41.949 103.485 53.156 1.00 76.98 ? 269 ILE A CB 1 ATOM 1853 C CG1 . ILE A 1 245 ? 41.321 102.929 51.860 1.00 78.65 ? 269 ILE A CG1 1 ATOM 1854 C CG2 . ILE A 1 245 ? 41.977 105.017 53.205 1.00 76.94 ? 269 ILE A CG2 1 ATOM 1855 C CD1 . ILE A 1 245 ? 42.020 103.294 50.538 1.00 85.60 ? 269 ILE A CD1 1 ATOM 1856 N N . ALA A 1 246 ? 44.828 104.139 54.892 1.00 76.13 ? 270 ALA A N 1 ATOM 1857 C CA . ALA A 1 246 ? 45.442 104.484 56.163 1.00 83.25 ? 270 ALA A CA 1 ATOM 1858 C C . ALA A 1 246 ? 45.196 105.903 56.650 1.00 85.08 ? 270 ALA A C 1 ATOM 1859 O O . ALA A 1 246 ? 45.151 106.848 55.856 1.00 87.18 ? 270 ALA A O 1 ATOM 1860 C CB . ALA A 1 246 ? 46.943 104.231 56.059 1.00 93.16 ? 270 ALA A CB 1 ATOM 1861 N N . SER A 1 247 ? 45.044 106.039 57.966 1.00 87.53 ? 271 SER A N 1 ATOM 1862 C CA . SER A 1 247 ? 44.840 107.338 58.605 1.00 84.53 ? 271 SER A CA 1 ATOM 1863 C C . SER A 1 247 ? 46.057 107.741 59.437 1.00 84.61 ? 271 SER A C 1 ATOM 1864 O O . SER A 1 247 ? 46.252 107.262 60.557 1.00 91.54 ? 271 SER A O 1 ATOM 1865 C CB . SER A 1 247 ? 43.606 107.313 59.510 1.00 84.18 ? 271 SER A CB 1 ATOM 1866 O OG . SER A 1 247 ? 43.709 106.297 60.493 1.00 80.98 ? 271 SER A OG 1 ATOM 1867 N N . GLY A 1 248 ? 46.876 108.621 58.875 1.00 88.23 ? 272 GLY A N 1 ATOM 1868 C CA . GLY A 1 248 ? 48.053 109.103 59.573 1.00 97.33 ? 272 GLY A CA 1 ATOM 1869 C C . GLY A 1 248 ? 48.283 110.579 59.310 1.00 110.86 ? 272 GLY A C 1 ATOM 1870 O O . GLY A 1 248 ? 47.935 111.082 58.237 1.00 101.89 ? 272 GLY A O 1 ATOM 1871 N N . VAL A 1 249 ? 48.866 111.280 60.287 1.00 151.36 ? 273 VAL A N 1 ATOM 1872 C CA . VAL A 1 249 ? 49.130 112.718 60.135 1.00 167.19 ? 273 VAL A CA 1 ATOM 1873 C C . VAL A 1 249 ? 50.155 112.876 59.005 1.00 165.93 ? 273 VAL A C 1 ATOM 1874 O O . VAL A 1 249 ? 49.804 113.423 57.950 1.00 189.52 ? 273 VAL A O 1 ATOM 1875 C CB . VAL A 1 249 ? 49.540 113.363 61.471 1.00 153.09 ? 273 VAL A CB 1 ATOM 1876 C CG1 . VAL A 1 249 ? 49.815 114.850 61.262 1.00 147.44 ? 273 VAL A CG1 1 ATOM 1877 C CG2 . VAL A 1 249 ? 48.404 113.170 62.495 1.00 147.70 ? 273 VAL A CG2 1 ATOM 1878 N N . PRO A 1 250 ? 51.429 112.472 59.201 1.00 126.61 ? 274 PRO A N 1 ATOM 1879 C CA . PRO A 1 250 ? 52.280 112.644 58.007 1.00 117.60 ? 274 PRO A CA 1 ATOM 1880 C C . PRO A 1 250 ? 51.656 111.605 57.043 1.00 118.23 ? 274 PRO A C 1 ATOM 1881 O O . PRO A 1 250 ? 51.716 110.392 57.303 1.00 120.98 ? 274 PRO A O 1 ATOM 1882 C CB . PRO A 1 250 ? 53.661 112.207 58.472 1.00 73.72 ? 274 PRO A CB 1 ATOM 1883 C CG . PRO A 1 250 ? 53.606 112.281 59.971 1.00 66.50 ? 274 PRO A CG 1 ATOM 1884 C CD . PRO A 1 250 ? 52.190 111.940 60.345 1.00 83.38 ? 274 PRO A CD 1 ATOM 1885 N N . THR A 1 251 ? 51.056 112.097 55.951 1.00 103.75 ? 275 THR A N 1 ATOM 1886 C CA . THR A 1 251 ? 50.289 111.267 55.005 1.00 100.47 ? 275 THR A CA 1 ATOM 1887 C C . THR A 1 251 ? 50.992 109.961 54.679 1.00 92.54 ? 275 THR A C 1 ATOM 1888 O O . THR A 1 251 ? 52.036 109.949 54.021 1.00 95.60 ? 275 THR A O 1 ATOM 1889 C CB . THR A 1 251 ? 49.908 112.078 53.750 1.00 88.73 ? 275 THR A CB 1 ATOM 1890 O OG1 . THR A 1 251 ? 49.024 113.148 54.134 1.00 89.97 ? 275 THR A OG1 1 ATOM 1891 C CG2 . THR A 1 251 ? 49.205 111.187 52.725 1.00 89.79 ? 275 THR A CG2 1 ATOM 1892 N N . PRO A 1 252 ? 50.411 108.834 55.145 1.00 75.53 ? 276 PRO A N 1 ATOM 1893 C CA . PRO A 1 252 ? 50.933 107.476 54.970 1.00 70.06 ? 276 PRO A CA 1 ATOM 1894 C C . PRO A 1 252 ? 51.131 107.008 53.563 1.00 69.25 ? 276 PRO A C 1 ATOM 1895 O O . PRO A 1 252 ? 50.418 107.438 52.671 1.00 62.85 ? 276 PRO A O 1 ATOM 1896 C CB . PRO A 1 252 ? 49.902 106.593 55.671 1.00 69.81 ? 276 PRO A CB 1 ATOM 1897 C CG . PRO A 1 252 ? 49.170 107.499 56.578 1.00 72.21 ? 276 PRO A CG 1 ATOM 1898 C CD . PRO A 1 252 ? 49.111 108.806 55.841 1.00 74.75 ? 276 PRO A CD 1 ATOM 1899 N N . ASP A 1 253 ? 52.106 106.120 53.381 1.00 81.48 ? 277 ASP A N 1 ATOM 1900 C CA . ASP A 1 253 ? 52.355 105.497 52.092 1.00 88.71 ? 277 ASP A CA 1 ATOM 1901 C C . ASP A 1 253 ? 51.989 104.013 52.216 1.00 87.48 ? 277 ASP A C 1 ATOM 1902 O O . ASP A 1 253 ? 52.193 103.404 53.268 1.00 90.83 ? 277 ASP A O 1 ATOM 1903 C CB . ASP A 1 253 ? 53.823 105.620 51.696 1.00 99.59 ? 277 ASP A CB 1 ATOM 1904 C CG . ASP A 1 253 ? 54.279 107.063 51.572 1.00 106.13 ? 277 ASP A CG 1 ATOM 1905 O OD1 . ASP A 1 253 ? 53.564 107.876 50.939 1.00 108.81 ? 277 ASP A OD1 1 ATOM 1906 O OD2 . ASP A 1 253 ? 55.368 107.379 52.098 1.00 108.74 ? 277 ASP A OD2 1 ATOM 1907 N N . ILE A 1 254 ? 51.453 103.441 51.139 1.00 75.24 ? 278 ILE A N 1 ATOM 1908 C CA . ILE A 1 254 ? 51.074 102.035 51.119 1.00 69.85 ? 278 ILE A CA 1 ATOM 1909 C C . ILE A 1 254 ? 52.058 101.243 50.259 1.00 65.97 ? 278 ILE A C 1 ATOM 1910 O O . ILE A 1 254 ? 52.536 101.745 49.244 1.00 64.13 ? 278 ILE A O 1 ATOM 1911 C CB . ILE A 1 254 ? 49.607 101.867 50.584 1.00 71.02 ? 278 ILE A CB 1 ATOM 1912 C CG1 . ILE A 1 254 ? 48.599 102.260 51.672 1.00 71.85 ? 278 ILE A CG1 1 ATOM 1913 C CG2 . ILE A 1 254 ? 49.328 100.438 50.163 1.00 70.36 ? 278 ILE A CG2 1 ATOM 1914 C CD1 . ILE A 1 254 ? 48.507 103.756 51.949 1.00 74.90 ? 278 ILE A CD1 1 ATOM 1915 N N . ALA A 1 255 ? 52.400 100.029 50.699 1.00 68.80 ? 279 ALA A N 1 ATOM 1916 C CA . ALA A 1 255 ? 53.296 99.138 49.944 1.00 69.05 ? 279 ALA A CA 1 ATOM 1917 C C . ALA A 1 255 ? 52.735 97.711 49.982 1.00 69.58 ? 279 ALA A C 1 ATOM 1918 O O . ALA A 1 255 ? 52.129 97.309 50.974 1.00 72.61 ? 279 ALA A O 1 ATOM 1919 C CB . ALA A 1 255 ? 54.704 99.195 50.484 1.00 59.01 ? 279 ALA A CB 1 ATOM 1920 N N . TRP A 1 256 ? 52.972 96.940 48.921 1.00 64.87 ? 280 TRP A N 1 ATOM 1921 C CA . TRP A 1 256 ? 52.346 95.625 48.778 1.00 61.43 ? 280 TRP A CA 1 ATOM 1922 C C . TRP A 1 256 ? 53.269 94.431 48.639 1.00 59.78 ? 280 TRP A C 1 ATOM 1923 O O . TRP A 1 256 ? 54.326 94.530 48.023 1.00 57.89 ? 280 TRP A O 1 ATOM 1924 C CB . TRP A 1 256 ? 51.388 95.675 47.568 1.00 64.08 ? 280 TRP A CB 1 ATOM 1925 C CG . TRP A 1 256 ? 50.203 96.562 47.778 1.00 65.75 ? 280 TRP A CG 1 ATOM 1926 C CD1 . TRP A 1 256 ? 50.101 97.882 47.472 1.00 67.14 ? 280 TRP A CD1 1 ATOM 1927 C CD2 . TRP A 1 256 ? 48.954 96.189 48.372 1.00 67.42 ? 280 TRP A CD2 1 ATOM 1928 N NE1 . TRP A 1 256 ? 48.866 98.359 47.834 1.00 67.55 ? 280 TRP A NE1 1 ATOM 1929 C CE2 . TRP A 1 256 ? 48.142 97.339 48.389 1.00 67.73 ? 280 TRP A CE2 1 ATOM 1930 C CE3 . TRP A 1 256 ? 48.443 94.992 48.894 1.00 67.46 ? 280 TRP A CE3 1 ATOM 1931 C CZ2 . TRP A 1 256 ? 46.846 97.332 48.906 1.00 67.78 ? 280 TRP A CZ2 1 ATOM 1932 C CZ3 . TRP A 1 256 ? 47.158 94.984 49.407 1.00 68.36 ? 280 TRP A CZ3 1 ATOM 1933 C CH2 . TRP A 1 256 ? 46.372 96.149 49.409 1.00 68.08 ? 280 TRP A CH2 1 ATOM 1934 N N . TYR A 1 257 ? 52.847 93.303 49.211 1.00 53.29 ? 281 TYR A N 1 ATOM 1935 C CA . TYR A 1 257 ? 53.620 92.071 49.179 1.00 53.96 ? 281 TYR A CA 1 ATOM 1936 C C . TYR A 1 257 ? 52.724 90.841 49.183 1.00 55.76 ? 281 TYR A C 1 ATOM 1937 O O . TYR A 1 257 ? 51.566 90.909 49.591 1.00 55.16 ? 281 TYR A O 1 ATOM 1938 C CB . TYR A 1 257 ? 54.512 91.944 50.437 1.00 57.72 ? 281 TYR A CB 1 ATOM 1939 C CG . TYR A 1 257 ? 55.390 93.134 50.774 1.00 59.82 ? 281 TYR A CG 1 ATOM 1940 C CD1 . TYR A 1 257 ? 54.900 94.190 51.544 1.00 59.51 ? 281 TYR A CD1 1 ATOM 1941 C CD2 . TYR A 1 257 ? 56.716 93.197 50.331 1.00 60.11 ? 281 TYR A CD2 1 ATOM 1942 C CE1 . TYR A 1 257 ? 55.703 95.281 51.868 1.00 60.15 ? 281 TYR A CE1 1 ATOM 1943 C CE2 . TYR A 1 257 ? 57.527 94.288 50.650 1.00 60.78 ? 281 TYR A CE2 1 ATOM 1944 C CZ . TYR A 1 257 ? 57.010 95.324 51.418 1.00 60.85 ? 281 TYR A CZ 1 ATOM 1945 O OH . TYR A 1 257 ? 57.791 96.412 51.733 1.00 61.87 ? 281 TYR A OH 1 ATOM 1946 N N . LYS A 1 258 ? 53.269 89.726 48.698 1.00 69.45 ? 282 LYS A N 1 ATOM 1947 C CA . LYS A 1 258 ? 52.607 88.428 48.813 1.00 73.06 ? 282 LYS A CA 1 ATOM 1948 C C . LYS A 1 258 ? 53.567 87.559 49.673 1.00 77.44 ? 282 LYS A C 1 ATOM 1949 O O . LYS A 1 258 ? 54.782 87.569 49.456 1.00 83.45 ? 282 LYS A O 1 ATOM 1950 C CB . LYS A 1 258 ? 52.370 87.776 47.452 1.00 58.60 ? 282 LYS A CB 1 ATOM 1951 C CG . LYS A 1 258 ? 51.552 86.489 47.518 1.00 53.68 ? 282 LYS A CG 1 ATOM 1952 C CD . LYS A 1 258 ? 51.288 85.913 46.135 1.00 49.98 ? 282 LYS A CD 1 ATOM 1953 C CE . LYS A 1 258 ? 50.556 84.588 46.230 1.00 49.34 ? 282 LYS A CE 1 ATOM 1954 N NZ . LYS A 1 258 ? 50.344 83.948 44.901 1.00 51.05 ? 282 LYS A NZ 1 ATOM 1955 N N . LYS A 1 259 ? 53.025 86.833 50.653 1.00 70.81 ? 283 LYS A N 1 ATOM 1956 C CA . LYS A 1 259 ? 53.845 85.998 51.534 1.00 71.47 ? 283 LYS A CA 1 ATOM 1957 C C . LYS A 1 259 ? 54.552 84.872 50.789 1.00 76.06 ? 283 LYS A C 1 ATOM 1958 O O . LYS A 1 259 ? 53.922 84.110 50.050 1.00 70.59 ? 283 LYS A O 1 ATOM 1959 C CB . LYS A 1 259 ? 53.008 85.410 52.692 1.00 76.39 ? 283 LYS A CB 1 ATOM 1960 C CG . LYS A 1 259 ? 52.779 86.381 53.855 1.00 81.51 ? 283 LYS A CG 1 ATOM 1961 C CD . LYS A 1 259 ? 52.094 85.699 55.038 1.00 83.58 ? 283 LYS A CD 1 ATOM 1962 C CE . LYS A 1 259 ? 51.875 86.668 56.200 1.00 84.11 ? 283 LYS A CE 1 ATOM 1963 N NZ . LYS A 1 259 ? 51.228 86.001 57.368 1.00 85.07 ? 283 LYS A NZ 1 ATOM 1964 N N . GLY A 1 260 ? 55.872 84.800 50.981 1.00 109.23 ? 284 GLY A N 1 ATOM 1965 C CA . GLY A 1 260 ? 56.701 83.771 50.363 1.00 120.61 ? 284 GLY A CA 1 ATOM 1966 C C . GLY A 1 260 ? 56.554 83.698 48.856 1.00 123.98 ? 284 GLY A C 1 ATOM 1967 O O . GLY A 1 260 ? 56.396 82.615 48.287 1.00 128.34 ? 284 GLY A O 1 ATOM 1968 N N . GLY A 1 261 ? 56.609 84.862 48.215 1.00 97.68 ? 285 GLY A N 1 ATOM 1969 C CA . GLY A 1 261 ? 56.454 84.945 46.775 1.00 93.33 ? 285 GLY A CA 1 ATOM 1970 C C . GLY A 1 261 ? 56.509 86.373 46.264 1.00 89.83 ? 285 GLY A C 1 ATOM 1971 O O . GLY A 1 261 ? 56.527 87.332 47.048 1.00 91.19 ? 285 GLY A O 1 ATOM 1972 N N . ASP A 1 262 ? 56.565 86.506 44.942 1.00 97.15 ? 286 ASP A N 1 ATOM 1973 C CA . ASP A 1 262 ? 56.573 87.811 44.298 1.00 98.27 ? 286 ASP A CA 1 ATOM 1974 C C . ASP A 1 262 ? 55.217 88.090 43.648 1.00 95.39 ? 286 ASP A C 1 ATOM 1975 O O . ASP A 1 262 ? 54.560 87.181 43.130 1.00 88.85 ? 286 ASP A O 1 ATOM 1976 C CB . ASP A 1 262 ? 57.665 87.882 43.217 1.00 105.75 ? 286 ASP A CB 1 ATOM 1977 C CG . ASP A 1 262 ? 59.047 88.151 43.790 1.00 114.45 ? 286 ASP A CG 1 ATOM 1978 O OD1 . ASP A 1 262 ? 59.210 89.136 44.549 1.00 118.19 ? 286 ASP A OD1 1 ATOM 1979 O OD2 . ASP A 1 262 ? 59.979 87.382 43.472 1.00 118.54 ? 286 ASP A OD2 1 ATOM 1980 N N . LEU A 1 263 ? 54.797 89.352 43.706 1.00 87.84 ? 287 LEU A N 1 ATOM 1981 C CA . LEU A 1 263 ? 53.561 89.784 43.051 1.00 90.86 ? 287 LEU A CA 1 ATOM 1982 C C . LEU A 1 263 ? 53.873 89.777 41.548 1.00 95.68 ? 287 LEU A C 1 ATOM 1983 O O . LEU A 1 263 ? 54.862 90.381 41.102 1.00 103.69 ? 287 LEU A O 1 ATOM 1984 C CB . LEU A 1 263 ? 53.166 91.187 43.512 1.00 87.07 ? 287 LEU A CB 1 ATOM 1985 C CG . LEU A 1 263 ? 53.423 91.531 44.981 1.00 75.88 ? 287 LEU A CG 1 ATOM 1986 C CD1 . LEU A 1 263 ? 54.734 92.319 45.117 1.00 70.56 ? 287 LEU A CD1 1 ATOM 1987 C CD2 . LEU A 1 263 ? 52.262 92.336 45.535 1.00 70.55 ? 287 LEU A CD2 1 ATOM 1988 N N . PRO A 1 264 ? 53.029 89.097 40.748 1.00 119.16 ? 288 PRO A N 1 ATOM 1989 C CA . PRO A 1 264 ? 53.245 89.011 39.292 1.00 123.54 ? 288 PRO A CA 1 ATOM 1990 C C . PRO A 1 264 ? 53.235 90.369 38.611 1.00 132.62 ? 288 PRO A C 1 ATOM 1991 O O . PRO A 1 264 ? 52.181 90.988 38.494 1.00 146.19 ? 288 PRO A O 1 ATOM 1992 C CB . PRO A 1 264 ? 52.129 88.078 38.823 1.00 84.29 ? 288 PRO A CB 1 ATOM 1993 C CG . PRO A 1 264 ? 51.049 88.229 39.858 1.00 73.51 ? 288 PRO A CG 1 ATOM 1994 C CD . PRO A 1 264 ? 51.759 88.465 41.159 1.00 80.23 ? 288 PRO A CD 1 ATOM 1995 N N . SER A 1 265 ? 54.405 90.816 38.146 1.00 125.45 ? 289 SER A N 1 ATOM 1996 C CA . SER A 1 265 ? 54.549 92.156 37.567 1.00 123.76 ? 289 SER A CA 1 ATOM 1997 C C . SER A 1 265 ? 53.709 92.436 36.328 1.00 120.02 ? 289 SER A C 1 ATOM 1998 O O . SER A 1 265 ? 53.439 93.600 36.014 1.00 117.45 ? 289 SER A O 1 ATOM 1999 C CB . SER A 1 265 ? 56.029 92.465 37.279 1.00 134.95 ? 289 SER A CB 1 ATOM 2000 O OG . SER A 1 265 ? 56.450 91.883 36.057 1.00 141.41 ? 289 SER A OG 1 ATOM 2001 N N . ASP A 1 266 ? 53.298 91.380 35.626 1.00 112.15 ? 290 ASP A N 1 ATOM 2002 C CA . ASP A 1 266 ? 52.464 91.537 34.435 1.00 107.83 ? 290 ASP A CA 1 ATOM 2003 C C . ASP A 1 266 ? 50.973 91.670 34.771 1.00 102.60 ? 290 ASP A C 1 ATOM 2004 O O . ASP A 1 266 ? 50.318 92.623 34.331 1.00 99.98 ? 290 ASP A O 1 ATOM 2005 C CB . ASP A 1 266 ? 52.681 90.372 33.449 1.00 122.78 ? 290 ASP A CB 1 ATOM 2006 C CG . ASP A 1 266 ? 52.768 89.020 34.136 1.00 128.21 ? 290 ASP A CG 1 ATOM 2007 O OD1 . ASP A 1 266 ? 53.709 88.813 34.939 1.00 131.59 ? 290 ASP A OD1 1 ATOM 2008 O OD2 . ASP A 1 266 ? 51.898 88.161 33.864 1.00 131.02 ? 290 ASP A OD2 1 ATOM 2009 N N . LYS A 1 267 ? 50.455 90.738 35.575 1.00 90.80 ? 291 LYS A N 1 ATOM 2010 C CA . LYS A 1 267 ? 49.041 90.726 35.951 1.00 82.57 ? 291 LYS A CA 1 ATOM 2011 C C . LYS A 1 267 ? 48.646 91.743 37.020 1.00 78.78 ? 291 LYS A C 1 ATOM 2012 O O . LYS A 1 267 ? 47.460 92.038 37.189 1.00 79.21 ? 291 LYS A O 1 ATOM 2013 C CB . LYS A 1 267 ? 48.645 89.324 36.419 1.00 77.27 ? 291 LYS A CB 1 ATOM 2014 C CG . LYS A 1 267 ? 48.546 88.305 35.302 1.00 73.62 ? 291 LYS A CG 1 ATOM 2015 C CD . LYS A 1 267 ? 48.404 86.891 35.846 1.00 72.84 ? 291 LYS A CD 1 ATOM 2016 C CE . LYS A 1 267 ? 47.038 86.653 36.458 1.00 71.49 ? 291 LYS A CE 1 ATOM 2017 N NZ . LYS A 1 267 ? 46.853 85.216 36.801 1.00 72.36 ? 291 LYS A NZ 1 ATOM 2018 N N . ALA A 1 268 ? 49.636 92.286 37.722 1.00 70.06 ? 292 ALA A N 1 ATOM 2019 C CA . ALA A 1 268 ? 49.374 93.236 38.796 1.00 68.29 ? 292 ALA A CA 1 ATOM 2020 C C . ALA A 1 268 ? 49.517 94.690 38.389 1.00 67.90 ? 292 ALA A C 1 ATOM 2021 O O . ALA A 1 268 ? 50.389 95.043 37.602 1.00 66.36 ? 292 ALA A O 1 ATOM 2022 C CB . ALA A 1 268 ? 50.293 92.940 39.995 1.00 81.23 ? 292 ALA A CB 1 ATOM 2023 N N . LYS A 1 269 ? 48.638 95.528 38.928 1.00 70.91 ? 293 LYS A N 1 ATOM 2024 C CA . LYS A 1 269 ? 48.678 96.951 38.669 1.00 73.42 ? 293 LYS A CA 1 ATOM 2025 C C . LYS A 1 269 ? 48.315 97.725 39.921 1.00 68.65 ? 293 LYS A C 1 ATOM 2026 O O . LYS A 1 269 ? 47.281 97.471 40.537 1.00 62.35 ? 293 LYS A O 1 ATOM 2027 C CB . LYS A 1 269 ? 47.706 97.333 37.542 1.00 102.58 ? 293 LYS A CB 1 ATOM 2028 C CG . LYS A 1 269 ? 48.217 97.047 36.132 1.00 120.49 ? 293 LYS A CG 1 ATOM 2029 C CD . LYS A 1 269 ? 47.125 97.273 35.085 1.00 129.22 ? 293 LYS A CD 1 ATOM 2030 C CE . LYS A 1 269 ? 47.706 97.492 33.690 1.00 131.42 ? 293 LYS A CE 1 ATOM 2031 N NZ . LYS A 1 269 ? 48.477 96.315 33.181 1.00 131.90 ? 293 LYS A NZ 1 ATOM 2032 N N . PHE A 1 270 ? 49.191 98.645 40.313 1.00 72.36 ? 294 PHE A N 1 ATOM 2033 C CA . PHE A 1 270 ? 48.928 99.528 41.438 1.00 75.77 ? 294 PHE A CA 1 ATOM 2034 C C . PHE A 1 270 ? 47.936 100.590 40.933 1.00 73.48 ? 294 PHE A C 1 ATOM 2035 O O . PHE A 1 270 ? 48.171 101.249 39.919 1.00 73.20 ? 294 PHE A O 1 ATOM 2036 C CB . PHE A 1 270 ? 50.230 100.188 41.913 1.00 85.52 ? 294 PHE A CB 1 ATOM 2037 C CG . PHE A 1 270 ? 51.261 99.198 42.383 1.00 94.39 ? 294 PHE A CG 1 ATOM 2038 C CD1 . PHE A 1 270 ? 52.144 98.601 41.479 1.00 98.35 ? 294 PHE A CD1 1 ATOM 2039 C CD2 . PHE A 1 270 ? 51.353 98.856 43.730 1.00 97.81 ? 294 PHE A CD2 1 ATOM 2040 C CE1 . PHE A 1 270 ? 53.109 97.676 41.912 1.00 99.19 ? 294 PHE A CE1 1 ATOM 2041 C CE2 . PHE A 1 270 ? 52.309 97.936 44.177 1.00 98.93 ? 294 PHE A CE2 1 ATOM 2042 C CZ . PHE A 1 270 ? 53.191 97.346 43.263 1.00 99.60 ? 294 PHE A CZ 1 ATOM 2043 N N . GLU A 1 271 ? 46.846 100.754 41.672 1.00 72.36 ? 295 GLU A N 1 ATOM 2044 C CA . GLU A 1 271 ? 45.834 101.751 41.377 1.00 71.23 ? 295 GLU A CA 1 ATOM 2045 C C . GLU A 1 271 ? 45.656 102.620 42.590 1.00 70.37 ? 295 GLU A C 1 ATOM 2046 O O . GLU A 1 271 ? 46.333 102.456 43.564 1.00 74.02 ? 295 GLU A O 1 ATOM 2047 C CB . GLU A 1 271 ? 44.500 101.098 41.088 1.00 68.77 ? 295 GLU A CB 1 ATOM 2048 C CG . GLU A 1 271 ? 44.446 100.345 39.798 1.00 64.13 ? 295 GLU A CG 1 ATOM 2049 C CD . GLU A 1 271 ? 43.095 99.798 39.540 1.00 61.72 ? 295 GLU A CD 1 ATOM 2050 O OE1 . GLU A 1 271 ? 42.139 100.231 40.194 1.00 60.45 ? 295 GLU A OE1 1 ATOM 2051 O OE2 . GLU A 1 271 ? 42.982 98.928 38.677 1.00 61.83 ? 295 GLU A OE2 1 ATOM 2052 N N . ASN A 1 272 ? 44.730 103.551 42.508 1.00 66.14 ? 296 ASN A N 1 ATOM 2053 C CA . ASN A 1 272 ? 44.381 104.435 43.599 1.00 64.99 ? 296 ASN A CA 1 ATOM 2054 C C . ASN A 1 272 ? 45.429 105.084 44.466 1.00 64.73 ? 296 ASN A C 1 ATOM 2055 O O . ASN A 1 272 ? 45.272 105.154 45.672 1.00 62.23 ? 296 ASN A O 1 ATOM 2056 C CB . ASN A 1 272 ? 43.369 103.741 44.502 1.00 68.51 ? 296 ASN A CB 1 ATOM 2057 C CG . ASN A 1 272 ? 42.565 104.711 45.309 1.00 70.35 ? 296 ASN A CG 1 ATOM 2058 O OD1 . ASN A 1 272 ? 42.660 105.908 45.132 1.00 72.20 ? 296 ASN A OD1 1 ATOM 2059 N ND2 . ASN A 1 272 ? 41.759 104.196 46.201 1.00 70.66 ? 296 ASN A ND2 1 ATOM 2060 N N . PHE A 1 273 ? 46.481 105.607 43.869 1.00 73.48 ? 297 PHE A N 1 ATOM 2061 C CA . PHE A 1 273 ? 47.477 106.315 44.655 1.00 76.93 ? 297 PHE A CA 1 ATOM 2062 C C . PHE A 1 273 ? 48.095 105.308 45.571 1.00 76.52 ? 297 PHE A C 1 ATOM 2063 O O . PHE A 1 273 ? 48.336 105.529 46.737 1.00 75.90 ? 297 PHE A O 1 ATOM 2064 C CB . PHE A 1 273 ? 46.893 107.463 45.467 1.00 79.94 ? 297 PHE A CB 1 ATOM 2065 C CG . PHE A 1 273 ? 46.487 108.612 44.644 1.00 84.59 ? 297 PHE A CG 1 ATOM 2066 C CD1 . PHE A 1 273 ? 45.233 108.667 44.096 1.00 86.79 ? 297 PHE A CD1 1 ATOM 2067 C CD2 . PHE A 1 273 ? 47.355 109.637 44.407 1.00 86.49 ? 297 PHE A CD2 1 ATOM 2068 C CE1 . PHE A 1 273 ? 44.862 109.723 43.339 1.00 87.36 ? 297 PHE A CE1 1 ATOM 2069 C CE2 . PHE A 1 273 ? 46.980 110.689 43.648 1.00 87.51 ? 297 PHE A CE2 1 ATOM 2070 C CZ . PHE A 1 273 ? 45.733 110.733 43.114 1.00 87.66 ? 297 PHE A CZ 1 ATOM 2071 N N . ASN A 1 274 ? 48.343 104.171 44.952 1.00 80.71 ? 298 ASN A N 1 ATOM 2072 C CA . ASN A 1 274 ? 48.996 102.989 45.491 1.00 81.60 ? 298 ASN A CA 1 ATOM 2073 C C . ASN A 1 274 ? 48.111 102.267 46.513 1.00 81.77 ? 298 ASN A C 1 ATOM 2074 O O . ASN A 1 274 ? 48.416 101.144 46.932 1.00 82.86 ? 298 ASN A O 1 ATOM 2075 C CB . ASN A 1 274 ? 50.378 103.312 46.100 1.00 79.33 ? 298 ASN A CB 1 ATOM 2076 C CG . ASN A 1 274 ? 51.440 102.314 45.658 1.00 81.43 ? 298 ASN A CG 1 ATOM 2077 O OD1 . ASN A 1 274 ? 51.951 101.524 46.463 1.00 82.83 ? 298 ASN A OD1 1 ATOM 2078 N ND2 . ASN A 1 274 ? 51.764 102.332 44.365 1.00 80.99 ? 298 ASN A ND2 1 ATOM 2079 N N . LYS A 1 275 ? 46.980 102.888 46.865 1.00 74.04 ? 299 LYS A N 1 ATOM 2080 C CA . LYS A 1 275 ? 46.061 102.357 47.875 1.00 70.14 ? 299 LYS A CA 1 ATOM 2081 C C . LYS A 1 275 ? 45.365 101.054 47.519 1.00 67.97 ? 299 LYS A C 1 ATOM 2082 O O . LYS A 1 275 ? 44.724 100.444 48.368 1.00 69.74 ? 299 LYS A O 1 ATOM 2083 C CB . LYS A 1 275 ? 45.008 103.415 48.243 1.00 67.21 ? 299 LYS A CB 1 ATOM 2084 C CG . LYS A 1 275 ? 45.573 104.635 48.965 1.00 65.57 ? 299 LYS A CG 1 ATOM 2085 C CD . LYS A 1 275 ? 44.493 105.653 49.279 1.00 63.94 ? 299 LYS A CD 1 ATOM 2086 C CE . LYS A 1 275 ? 45.092 107.035 49.388 1.00 63.87 ? 299 LYS A CE 1 ATOM 2087 N NZ . LYS A 1 275 ? 44.098 108.053 49.824 1.00 64.55 ? 299 LYS A NZ 1 ATOM 2088 N N . ALA A 1 276 ? 45.505 100.620 46.271 1.00 57.21 ? 300 ALA A N 1 ATOM 2089 C CA . ALA A 1 276 ? 44.869 99.385 45.828 1.00 51.28 ? 300 ALA A CA 1 ATOM 2090 C C . ALA A 1 276 ? 45.734 98.595 44.841 1.00 50.13 ? 300 ALA A C 1 ATOM 2091 O O . ALA A 1 276 ? 46.603 99.153 44.169 1.00 46.47 ? 300 ALA A O 1 ATOM 2092 C CB . ALA A 1 276 ? 43.497 99.695 45.214 1.00 41.71 ? 300 ALA A CB 1 ATOM 2093 N N . LEU A 1 277 ? 45.475 97.293 44.756 1.00 51.44 ? 301 LEU A N 1 ATOM 2094 C CA . LEU A 1 277 ? 46.237 96.411 43.891 1.00 54.90 ? 301 LEU A CA 1 ATOM 2095 C C . LEU A 1 277 ? 45.327 95.448 43.141 1.00 54.06 ? 301 LEU A C 1 ATOM 2096 O O . LEU A 1 277 ? 44.632 94.628 43.741 1.00 52.03 ? 301 LEU A O 1 ATOM 2097 C CB . LEU A 1 277 ? 47.234 95.616 44.741 1.00 63.12 ? 301 LEU A CB 1 ATOM 2098 C CG . LEU A 1 277 ? 48.376 94.819 44.100 1.00 71.40 ? 301 LEU A CG 1 ATOM 2099 C CD1 . LEU A 1 277 ? 49.220 94.231 45.211 1.00 76.20 ? 301 LEU A CD1 1 ATOM 2100 C CD2 . LEU A 1 277 ? 47.877 93.702 43.197 1.00 76.64 ? 301 LEU A CD2 1 ATOM 2101 N N . ARG A 1 278 ? 45.334 95.542 41.820 1.00 54.63 ? 302 ARG A N 1 ATOM 2102 C CA . ARG A 1 278 ? 44.511 94.659 41.011 1.00 55.57 ? 302 ARG A CA 1 ATOM 2103 C C . ARG A 1 278 ? 45.364 93.589 40.366 1.00 54.87 ? 302 ARG A C 1 ATOM 2104 O O . ARG A 1 278 ? 46.472 93.860 39.924 1.00 54.87 ? 302 ARG A O 1 ATOM 2105 C CB . ARG A 1 278 ? 43.785 95.452 39.903 1.00 55.64 ? 302 ARG A CB 1 ATOM 2106 C CG . ARG A 1 278 ? 42.861 94.614 39.012 1.00 54.14 ? 302 ARG A CG 1 ATOM 2107 C CD . ARG A 1 278 ? 42.164 95.470 37.938 1.00 54.34 ? 302 ARG A CD 1 ATOM 2108 N NE . ARG A 1 278 ? 41.556 96.666 38.524 1.00 52.43 ? 302 ARG A NE 1 ATOM 2109 C CZ . ARG A 1 278 ? 40.261 96.820 38.762 1.00 51.16 ? 302 ARG A CZ 1 ATOM 2110 N NH1 . ARG A 1 278 ? 39.396 95.853 38.451 1.00 49.76 ? 302 ARG A NH1 1 ATOM 2111 N NH2 . ARG A 1 278 ? 39.844 97.946 39.339 1.00 48.75 ? 302 ARG A NH2 1 ATOM 2112 N N . ILE A 1 279 ? 44.841 92.368 40.359 1.00 55.86 ? 303 ILE A N 1 ATOM 2113 C CA . ILE A 1 279 ? 45.467 91.229 39.673 1.00 57.24 ? 303 ILE A CA 1 ATOM 2114 C C . ILE A 1 279 ? 44.369 90.776 38.697 1.00 61.76 ? 303 ILE A C 1 ATOM 2115 O O . ILE A 1 279 ? 43.253 90.446 39.111 1.00 61.73 ? 303 ILE A O 1 ATOM 2116 C CB . ILE A 1 279 ? 45.908 90.137 40.660 1.00 54.65 ? 303 ILE A CB 1 ATOM 2117 C CG1 . ILE A 1 279 ? 47.162 90.620 41.401 1.00 54.39 ? 303 ILE A CG1 1 ATOM 2118 C CG2 . ILE A 1 279 ? 46.215 88.843 39.920 1.00 48.37 ? 303 ILE A CG2 1 ATOM 2119 C CD1 . ILE A 1 279 ? 47.512 89.823 42.655 1.00 65.52 ? 303 ILE A CD1 1 ATOM 2120 N N . THR A 1 280 ? 44.713 90.738 37.411 1.00 76.50 ? 304 THR A N 1 ATOM 2121 C CA . THR A 1 280 ? 43.706 90.572 36.377 1.00 82.36 ? 304 THR A CA 1 ATOM 2122 C C . THR A 1 280 ? 43.023 89.236 36.181 1.00 80.19 ? 304 THR A C 1 ATOM 2123 O O . THR A 1 280 ? 41.940 89.013 36.706 1.00 85.59 ? 304 THR A O 1 ATOM 2124 C CB . THR A 1 280 ? 44.237 91.097 34.992 1.00 86.25 ? 304 THR A CB 1 ATOM 2125 O OG1 . THR A 1 280 ? 45.229 92.118 35.192 1.00 90.07 ? 304 THR A OG1 1 ATOM 2126 C CG2 . THR A 1 280 ? 43.087 91.684 34.167 1.00 90.08 ? 304 THR A CG2 1 ATOM 2127 N N . ASN A 1 281 ? 43.637 88.335 35.440 1.00 69.85 ? 305 ASN A N 1 ATOM 2128 C CA . ASN A 1 281 ? 42.990 87.058 35.139 1.00 66.13 ? 305 ASN A CA 1 ATOM 2129 C C . ASN A 1 281 ? 43.428 86.025 36.166 1.00 62.25 ? 305 ASN A C 1 ATOM 2130 O O . ASN A 1 281 ? 44.194 85.108 35.858 1.00 60.09 ? 305 ASN A O 1 ATOM 2131 C CB . ASN A 1 281 ? 43.367 86.635 33.704 1.00 70.02 ? 305 ASN A CB 1 ATOM 2132 C CG . ASN A 1 281 ? 42.833 85.255 33.325 1.00 72.00 ? 305 ASN A CG 1 ATOM 2133 O OD1 . ASN A 1 281 ? 43.493 84.504 32.599 1.00 73.53 ? 305 ASN A OD1 1 ATOM 2134 N ND2 . ASN A 1 281 ? 41.637 84.918 33.804 1.00 73.50 ? 305 ASN A ND2 1 ATOM 2135 N N . VAL A 1 282 ? 42.904 86.166 37.385 1.00 57.94 ? 306 VAL A N 1 ATOM 2136 C CA . VAL A 1 282 ? 43.326 85.308 38.488 1.00 55.85 ? 306 VAL A CA 1 ATOM 2137 C C . VAL A 1 282 ? 43.081 83.836 38.279 1.00 55.27 ? 306 VAL A C 1 ATOM 2138 O O . VAL A 1 282 ? 42.089 83.447 37.669 1.00 54.79 ? 306 VAL A O 1 ATOM 2139 C CB . VAL A 1 282 ? 42.654 85.698 39.844 1.00 46.68 ? 306 VAL A CB 1 ATOM 2140 C CG1 . VAL A 1 282 ? 42.850 87.173 40.136 1.00 42.53 ? 306 VAL A CG1 1 ATOM 2141 C CG2 . VAL A 1 282 ? 41.194 85.324 39.833 1.00 41.96 ? 306 VAL A CG2 1 ATOM 2142 N N . SER A 1 283 ? 44.032 83.032 38.753 1.00 55.59 ? 307 SER A N 1 ATOM 2143 C CA . SER A 1 283 ? 43.896 81.580 38.747 1.00 56.24 ? 307 SER A CA 1 ATOM 2144 C C . SER A 1 283 ? 44.333 81.065 40.132 1.00 53.95 ? 307 SER A C 1 ATOM 2145 O O . SER A 1 283 ? 44.734 81.846 40.997 1.00 50.34 ? 307 SER A O 1 ATOM 2146 C CB . SER A 1 283 ? 44.754 80.938 37.666 1.00 65.12 ? 307 SER A CB 1 ATOM 2147 O OG . SER A 1 283 ? 46.122 80.983 38.018 1.00 70.06 ? 307 SER A OG 1 ATOM 2148 N N . GLU A 1 284 ? 44.246 79.750 40.315 1.00 55.98 ? 308 GLU A N 1 ATOM 2149 C CA . GLU A 1 284 ? 44.633 79.060 41.551 1.00 61.23 ? 308 GLU A CA 1 ATOM 2150 C C . GLU A 1 284 ? 45.966 79.569 42.120 1.00 63.37 ? 308 GLU A C 1 ATOM 2151 O O . GLU A 1 284 ? 46.078 79.818 43.314 1.00 61.63 ? 308 GLU A O 1 ATOM 2152 C CB . GLU A 1 284 ? 44.723 77.544 41.302 1.00 67.35 ? 308 GLU A CB 1 ATOM 2153 C CG . GLU A 1 284 ? 43.520 76.916 40.557 1.00 73.90 ? 308 GLU A CG 1 ATOM 2154 C CD . GLU A 1 284 ? 43.608 77.012 39.014 1.00 77.04 ? 308 GLU A CD 1 ATOM 2155 O OE1 . GLU A 1 284 ? 43.314 78.098 38.456 1.00 76.54 ? 308 GLU A OE1 1 ATOM 2156 O OE2 . GLU A 1 284 ? 43.970 75.999 38.363 1.00 76.71 ? 308 GLU A OE2 1 ATOM 2157 N N . GLU A 1 285 ? 46.960 79.743 41.253 1.00 69.26 ? 309 GLU A N 1 ATOM 2158 C CA . GLU A 1 285 ? 48.291 80.227 41.637 1.00 71.48 ? 309 GLU A CA 1 ATOM 2159 C C . GLU A 1 285 ? 48.272 81.559 42.373 1.00 68.72 ? 309 GLU A C 1 ATOM 2160 O O . GLU A 1 285 ? 49.196 81.874 43.127 1.00 67.63 ? 309 GLU A O 1 ATOM 2161 C CB . GLU A 1 285 ? 49.168 80.394 40.387 1.00 95.70 ? 309 GLU A CB 1 ATOM 2162 C CG . GLU A 1 285 ? 48.939 79.332 39.308 1.00 109.57 ? 309 GLU A CG 1 ATOM 2163 C CD . GLU A 1 285 ? 49.994 79.355 38.204 1.00 115.80 ? 309 GLU A CD 1 ATOM 2164 O OE1 . GLU A 1 285 ? 50.358 80.462 37.732 1.00 117.93 ? 309 GLU A OE1 1 ATOM 2165 O OE2 . GLU A 1 285 ? 50.446 78.256 37.804 1.00 117.12 ? 309 GLU A OE2 1 ATOM 2166 N N . ASP A 1 286 ? 47.215 82.337 42.159 1.00 59.67 ? 310 ASP A N 1 ATOM 2167 C CA . ASP A 1 286 ? 47.115 83.676 42.729 1.00 53.47 ? 310 ASP A CA 1 ATOM 2168 C C . ASP A 1 286 ? 46.543 83.725 44.130 1.00 48.13 ? 310 ASP A C 1 ATOM 2169 O O . ASP A 1 286 ? 46.490 84.787 44.746 1.00 43.33 ? 310 ASP A O 1 ATOM 2170 C CB . ASP A 1 286 ? 46.331 84.591 41.780 1.00 66.74 ? 310 ASP A CB 1 ATOM 2171 C CG . ASP A 1 286 ? 47.103 84.918 40.510 1.00 72.17 ? 310 ASP A CG 1 ATOM 2172 O OD1 . ASP A 1 286 ? 48.227 85.458 40.624 1.00 76.48 ? 310 ASP A OD1 1 ATOM 2173 O OD2 . ASP A 1 286 ? 46.580 84.636 39.405 1.00 74.22 ? 310 ASP A OD2 1 ATOM 2174 N N . SER A 1 287 ? 46.119 82.567 44.632 1.00 44.70 ? 311 SER A N 1 ATOM 2175 C CA . SER A 1 287 ? 45.628 82.471 46.007 1.00 46.90 ? 311 SER A CA 1 ATOM 2176 C C . SER A 1 287 ? 46.793 82.529 47.013 1.00 47.15 ? 311 SER A C 1 ATOM 2177 O O . SER A 1 287 ? 47.973 82.392 46.641 1.00 44.22 ? 311 SER A O 1 ATOM 2178 C CB . SER A 1 287 ? 44.814 81.188 46.216 1.00 57.84 ? 311 SER A CB 1 ATOM 2179 O OG . SER A 1 287 ? 45.563 80.034 45.912 1.00 65.26 ? 311 SER A OG 1 ATOM 2180 N N . GLY A 1 288 ? 46.451 82.748 48.284 1.00 53.69 ? 312 GLY A N 1 ATOM 2181 C CA . GLY A 1 288 ? 47.458 82.855 49.325 1.00 59.93 ? 312 GLY A CA 1 ATOM 2182 C C . GLY A 1 288 ? 47.377 84.170 50.068 1.00 62.61 ? 312 GLY A C 1 ATOM 2183 O O . GLY A 1 288 ? 46.456 84.952 49.852 1.00 65.19 ? 312 GLY A O 1 ATOM 2184 N N . GLU A 1 289 ? 48.369 84.433 50.908 1.00 60.09 ? 313 GLU A N 1 ATOM 2185 C CA . GLU A 1 289 ? 48.352 85.609 51.764 1.00 58.72 ? 313 GLU A CA 1 ATOM 2186 C C . GLU A 1 289 ? 49.059 86.815 51.181 1.00 58.27 ? 313 GLU A C 1 ATOM 2187 O O . GLU A 1 289 ? 50.222 86.739 50.787 1.00 58.79 ? 313 GLU A O 1 ATOM 2188 C CB . GLU A 1 289 ? 48.970 85.272 53.148 1.00 58.63 ? 313 GLU A CB 1 ATOM 2189 C CG . GLU A 1 289 ? 48.595 83.897 53.714 1.00 62.46 ? 313 GLU A CG 1 ATOM 2190 C CD . GLU A 1 289 ? 47.090 83.693 53.911 1.00 63.71 ? 313 GLU A CD 1 ATOM 2191 O OE1 . GLU A 1 289 ? 46.491 84.421 54.746 1.00 63.80 ? 313 GLU A OE1 1 ATOM 2192 O OE2 . GLU A 1 289 ? 46.512 82.798 53.238 1.00 62.52 ? 313 GLU A OE2 1 ATOM 2193 N N . TYR A 1 290 ? 48.329 87.922 51.098 1.00 59.86 ? 314 TYR A N 1 ATOM 2194 C CA . TYR A 1 290 ? 48.900 89.180 50.655 1.00 56.79 ? 314 TYR A CA 1 ATOM 2195 C C . TYR A 1 290 ? 48.875 90.106 51.863 1.00 56.30 ? 314 TYR A C 1 ATOM 2196 O O . TYR A 1 290 ? 48.034 89.939 52.755 1.00 56.90 ? 314 TYR A O 1 ATOM 2197 C CB . TYR A 1 290 ? 48.058 89.820 49.545 1.00 48.31 ? 314 TYR A CB 1 ATOM 2198 C CG . TYR A 1 290 ? 48.001 88.997 48.289 1.00 46.72 ? 314 TYR A CG 1 ATOM 2199 C CD1 . TYR A 1 290 ? 47.161 87.891 48.197 1.00 44.02 ? 314 TYR A CD1 1 ATOM 2200 C CD2 . TYR A 1 290 ? 48.797 89.324 47.180 1.00 45.31 ? 314 TYR A CD2 1 ATOM 2201 C CE1 . TYR A 1 290 ? 47.109 87.129 47.035 1.00 45.53 ? 314 TYR A CE1 1 ATOM 2202 C CE2 . TYR A 1 290 ? 48.751 88.567 46.019 1.00 42.28 ? 314 TYR A CE2 1 ATOM 2203 C CZ . TYR A 1 290 ? 47.906 87.473 45.956 1.00 44.12 ? 314 TYR A CZ 1 ATOM 2204 O OH . TYR A 1 290 ? 47.859 86.701 44.826 1.00 45.93 ? 314 TYR A OH 1 ATOM 2205 N N . PHE A 1 291 ? 49.808 91.054 51.912 1.00 48.12 ? 315 PHE A N 1 ATOM 2206 C CA . PHE A 1 291 ? 49.796 92.038 52.983 1.00 45.82 ? 315 PHE A CA 1 ATOM 2207 C C . PHE A 1 291 ? 50.285 93.399 52.531 1.00 47.95 ? 315 PHE A C 1 ATOM 2208 O O . PHE A 1 291 ? 51.011 93.504 51.537 1.00 45.75 ? 315 PHE A O 1 ATOM 2209 C CB . PHE A 1 291 ? 50.560 91.549 54.228 1.00 55.28 ? 315 PHE A CB 1 ATOM 2210 C CG . PHE A 1 291 ? 52.051 91.414 54.050 1.00 57.85 ? 315 PHE A CG 1 ATOM 2211 C CD1 . PHE A 1 291 ? 52.901 92.467 54.373 1.00 58.65 ? 315 PHE A CD1 1 ATOM 2212 C CD2 . PHE A 1 291 ? 52.602 90.218 53.604 1.00 59.23 ? 315 PHE A CD2 1 ATOM 2213 C CE1 . PHE A 1 291 ? 54.280 92.341 54.240 1.00 59.57 ? 315 PHE A CE1 1 ATOM 2214 C CE2 . PHE A 1 291 ? 53.981 90.075 53.464 1.00 61.18 ? 315 PHE A CE2 1 ATOM 2215 C CZ . PHE A 1 291 ? 54.825 91.137 53.789 1.00 61.21 ? 315 PHE A CZ 1 ATOM 2216 N N . CYS A 1 292 ? 49.861 94.431 53.254 1.00 51.53 ? 316 CYS A N 1 ATOM 2217 C CA . CYS A 1 292 ? 50.223 95.797 52.933 1.00 58.35 ? 316 CYS A CA 1 ATOM 2218 C C . CYS A 1 292 ? 50.770 96.539 54.151 1.00 61.28 ? 316 CYS A C 1 ATOM 2219 O O . CYS A 1 292 ? 50.456 96.197 55.298 1.00 62.97 ? 316 CYS A O 1 ATOM 2220 C CB . CYS A 1 292 ? 49.002 96.561 52.389 1.00 67.06 ? 316 CYS A CB 1 ATOM 2221 S SG . CYS A 1 292 ? 47.814 97.052 53.683 1.00 73.71 ? 316 CYS A SG 1 ATOM 2222 N N . LEU A 1 293 ? 51.587 97.558 53.893 1.00 65.84 ? 317 LEU A N 1 ATOM 2223 C CA . LEU A 1 293 ? 52.153 98.361 54.953 1.00 67.44 ? 317 LEU A CA 1 ATOM 2224 C C . LEU A 1 293 ? 51.824 99.839 54.837 1.00 67.45 ? 317 LEU A C 1 ATOM 2225 O O . LEU A 1 293 ? 52.081 100.469 53.808 1.00 66.72 ? 317 LEU A O 1 ATOM 2226 C CB . LEU A 1 293 ? 53.681 98.206 55.001 1.00 80.29 ? 317 LEU A CB 1 ATOM 2227 C CG . LEU A 1 293 ? 54.257 97.178 55.984 1.00 84.56 ? 317 LEU A CG 1 ATOM 2228 C CD1 . LEU A 1 293 ? 54.197 95.766 55.411 1.00 85.90 ? 317 LEU A CD1 1 ATOM 2229 C CD2 . LEU A 1 293 ? 55.690 97.572 56.303 1.00 86.74 ? 317 LEU A CD2 1 ATOM 2230 N N . ALA A 1 294 ? 51.232 100.373 55.904 1.00 68.96 ? 318 ALA A N 1 ATOM 2231 C CA . ALA A 1 294 ? 50.956 101.802 56.003 1.00 70.77 ? 318 ALA A CA 1 ATOM 2232 C C . ALA A 1 294 ? 52.200 102.442 56.637 1.00 74.36 ? 318 ALA A C 1 ATOM 2233 O O . ALA A 1 294 ? 52.241 102.711 57.841 1.00 72.30 ? 318 ALA A O 1 ATOM 2234 C CB . ALA A 1 294 ? 49.741 102.052 56.860 1.00 72.60 ? 318 ALA A CB 1 ATOM 2235 N N . SER A 1 295 ? 53.203 102.694 55.796 1.00 88.40 ? 319 SER A N 1 ATOM 2236 C CA . SER A 1 295 ? 54.468 103.244 56.243 1.00 96.99 ? 319 SER A CA 1 ATOM 2237 C C . SER A 1 295 ? 54.479 104.746 56.511 1.00 99.63 ? 319 SER A C 1 ATOM 2238 O O . SER A 1 295 ? 54.785 105.556 55.632 1.00 98.55 ? 319 SER A O 1 ATOM 2239 C CB . SER A 1 295 ? 55.594 102.856 55.256 1.00 108.53 ? 319 SER A CB 1 ATOM 2240 O OG . SER A 1 295 ? 55.267 103.201 53.921 1.00 118.03 ? 319 SER A OG 1 ATOM 2241 N N . ASN A 1 296 ? 54.126 105.098 57.745 1.00 97.50 ? 320 ASN A N 1 ATOM 2242 C CA . ASN A 1 296 ? 54.153 106.484 58.226 1.00 101.41 ? 320 ASN A CA 1 ATOM 2243 C C . ASN A 1 296 ? 55.605 106.893 58.582 1.00 104.60 ? 320 ASN A C 1 ATOM 2244 O O . ASN A 1 296 ? 56.577 106.339 58.053 1.00 107.55 ? 320 ASN A O 1 ATOM 2245 C CB . ASN A 1 296 ? 53.285 106.596 59.489 1.00 110.56 ? 320 ASN A CB 1 ATOM 2246 C CG . ASN A 1 296 ? 52.813 108.017 59.760 1.00 107.20 ? 320 ASN A CG 1 ATOM 2247 O OD1 . ASN A 1 296 ? 53.257 108.970 59.121 1.00 105.31 ? 320 ASN A OD1 1 ATOM 2248 N ND2 . ASN A 1 296 ? 51.902 108.160 60.715 1.00 105.10 ? 320 ASN A ND2 1 ATOM 2249 N N . LYS A 1 297 ? 55.726 107.882 59.469 1.00 109.38 ? 321 LYS A N 1 ATOM 2250 C CA . LYS A 1 297 ? 57.015 108.358 59.971 1.00 106.99 ? 321 LYS A CA 1 ATOM 2251 C C . LYS A 1 297 ? 57.156 107.864 61.418 1.00 107.14 ? 321 LYS A C 1 ATOM 2252 O O . LYS A 1 297 ? 58.213 107.379 61.812 1.00 110.33 ? 321 LYS A O 1 ATOM 2253 C CB . LYS A 1 297 ? 57.078 109.883 59.918 1.00 103.23 ? 321 LYS A CB 1 ATOM 2254 C CG . LYS A 1 297 ? 58.484 110.466 59.984 1.00 99.00 ? 321 LYS A CG 1 ATOM 2255 C CD . LYS A 1 297 ? 58.480 111.975 59.667 1.00 97.78 ? 321 LYS A CD 1 ATOM 2256 C CE . LYS A 1 297 ? 57.948 112.817 60.839 1.00 98.27 ? 321 LYS A CE 1 ATOM 2257 N NZ . LYS A 1 297 ? 57.894 114.282 60.537 1.00 98.28 ? 321 LYS A NZ 1 ATOM 2258 N N . MET A 1 298 ? 56.076 107.984 62.188 1.00 100.32 ? 322 MET A N 1 ATOM 2259 C CA . MET A 1 298 ? 56.024 107.528 63.581 1.00 99.67 ? 322 MET A CA 1 ATOM 2260 C C . MET A 1 298 ? 55.818 106.013 63.719 1.00 96.04 ? 322 MET A C 1 ATOM 2261 O O . MET A 1 298 ? 55.885 105.477 64.829 1.00 92.16 ? 322 MET A O 1 ATOM 2262 C CB . MET A 1 298 ? 54.888 108.243 64.333 1.00 126.79 ? 322 MET A CB 1 ATOM 2263 C CG . MET A 1 298 ? 55.329 109.388 65.249 1.00 139.21 ? 322 MET A CG 1 ATOM 2264 S SD . MET A 1 298 ? 56.370 110.640 64.453 1.00 145.69 ? 322 MET A SD 1 ATOM 2265 C CE . MET A 1 298 ? 55.330 111.167 63.095 1.00 147.84 ? 322 MET A CE 1 ATOM 2266 N N . GLY A 1 299 ? 55.567 105.333 62.600 1.00 99.08 ? 323 GLY A N 1 ATOM 2267 C CA . GLY A 1 299 ? 55.326 103.898 62.637 1.00 96.58 ? 323 GLY A CA 1 ATOM 2268 C C . GLY A 1 299 ? 55.044 103.263 61.284 1.00 93.69 ? 323 GLY A C 1 ATOM 2269 O O . GLY A 1 299 ? 55.132 103.920 60.244 1.00 94.83 ? 323 GLY A O 1 ATOM 2270 N N . SER A 1 300 ? 54.689 101.980 61.314 1.00 95.03 ? 324 SER A N 1 ATOM 2271 C CA . SER A 1 300 ? 54.434 101.198 60.111 1.00 90.20 ? 324 SER A CA 1 ATOM 2272 C C . SER A 1 300 ? 53.689 99.909 60.477 1.00 90.63 ? 324 SER A C 1 ATOM 2273 O O . SER A 1 300 ? 54.294 98.942 60.959 1.00 91.74 ? 324 SER A O 1 ATOM 2274 C CB . SER A 1 300 ? 55.774 100.873 59.427 1.00 79.82 ? 324 SER A CB 1 ATOM 2275 O OG . SER A 1 300 ? 55.644 99.833 58.471 1.00 76.63 ? 324 SER A OG 1 ATOM 2276 N N . ILE A 1 301 ? 52.370 99.905 60.258 1.00 84.06 ? 325 ILE A N 1 ATOM 2277 C CA . ILE A 1 301 ? 51.542 98.739 60.579 1.00 78.65 ? 325 ILE A CA 1 ATOM 2278 C C . ILE A 1 301 ? 51.255 97.881 59.357 1.00 78.67 ? 325 ILE A C 1 ATOM 2279 O O . ILE A 1 301 ? 51.604 98.255 58.231 1.00 79.69 ? 325 ILE A O 1 ATOM 2280 C CB . ILE A 1 301 ? 50.217 99.133 61.286 1.00 78.93 ? 325 ILE A CB 1 ATOM 2281 C CG1 . ILE A 1 301 ? 49.399 100.077 60.410 1.00 78.07 ? 325 ILE A CG1 1 ATOM 2282 C CG2 . ILE A 1 301 ? 50.529 99.768 62.646 1.00 78.25 ? 325 ILE A CG2 1 ATOM 2283 C CD1 . ILE A 1 301 ? 47.947 100.254 60.847 1.00 79.47 ? 325 ILE A CD1 1 ATOM 2284 N N . ARG A 1 302 ? 50.629 96.729 59.577 1.00 78.53 ? 326 ARG A N 1 ATOM 2285 C CA . ARG A 1 302 ? 50.386 95.801 58.484 1.00 73.11 ? 326 ARG A CA 1 ATOM 2286 C C . ARG A 1 302 ? 49.000 95.166 58.507 1.00 69.96 ? 326 ARG A C 1 ATOM 2287 O O . ARG A 1 302 ? 48.426 94.923 59.576 1.00 71.72 ? 326 ARG A O 1 ATOM 2288 C CB . ARG A 1 302 ? 51.493 94.708 58.492 1.00 63.13 ? 326 ARG A CB 1 ATOM 2289 C CG . ARG A 1 302 ? 51.074 93.322 58.952 1.00 62.82 ? 326 ARG A CG 1 ATOM 2290 C CD . ARG A 1 302 ? 51.220 92.319 57.820 1.00 61.65 ? 326 ARG A CD 1 ATOM 2291 N NE . ARG A 1 302 ? 52.358 91.407 57.977 1.00 61.33 ? 326 ARG A NE 1 ATOM 2292 C CZ . ARG A 1 302 ? 53.639 91.736 57.840 1.00 60.50 ? 326 ARG A CZ 1 ATOM 2293 N NH1 . ARG A 1 302 ? 53.991 92.972 57.540 1.00 62.84 ? 326 ARG A NH1 1 ATOM 2294 N NH2 . ARG A 1 302 ? 54.574 90.817 57.993 1.00 60.06 ? 326 ARG A NH2 1 ATOM 2295 N N . HIS A 1 303 ? 48.453 94.942 57.314 1.00 59.40 ? 327 HIS A N 1 ATOM 2296 C CA . HIS A 1 303 ? 47.164 94.278 57.186 1.00 55.56 ? 327 HIS A CA 1 ATOM 2297 C C . HIS A 1 303 ? 47.392 93.032 56.356 1.00 52.09 ? 327 HIS A C 1 ATOM 2298 O O . HIS A 1 303 ? 48.149 93.065 55.387 1.00 51.19 ? 327 HIS A O 1 ATOM 2299 C CB . HIS A 1 303 ? 46.148 95.172 56.501 1.00 54.82 ? 327 HIS A CB 1 ATOM 2300 C CG . HIS A 1 303 ? 44.734 94.711 56.671 1.00 56.26 ? 327 HIS A CG 1 ATOM 2301 N ND1 . HIS A 1 303 ? 44.121 93.837 55.798 1.00 56.04 ? 327 HIS A ND1 1 ATOM 2302 C CD2 . HIS A 1 303 ? 43.814 94.996 57.626 1.00 56.59 ? 327 HIS A CD2 1 ATOM 2303 C CE1 . HIS A 1 303 ? 42.885 93.606 56.204 1.00 54.90 ? 327 HIS A CE1 1 ATOM 2304 N NE2 . HIS A 1 303 ? 42.674 94.298 57.311 1.00 55.07 ? 327 HIS A NE2 1 ATOM 2305 N N . THR A 1 304 ? 46.758 91.931 56.740 1.00 52.96 ? 328 THR A N 1 ATOM 2306 C CA . THR A 1 304 ? 46.924 90.694 56.012 1.00 52.56 ? 328 THR A CA 1 ATOM 2307 C C . THR A 1 304 ? 45.608 90.259 55.391 1.00 52.67 ? 328 THR A C 1 ATOM 2308 O O . THR A 1 304 ? 44.578 90.188 56.067 1.00 54.81 ? 328 THR A O 1 ATOM 2309 C CB . THR A 1 304 ? 47.507 89.589 56.927 1.00 50.13 ? 328 THR A CB 1 ATOM 2310 O OG1 . THR A 1 304 ? 48.755 90.055 57.458 1.00 52.01 ? 328 THR A OG1 1 ATOM 2311 C CG2 . THR A 1 304 ? 47.764 88.298 56.143 1.00 46.36 ? 328 THR A CG2 1 ATOM 2312 N N . ILE A 1 305 ? 45.647 89.998 54.087 1.00 48.94 ? 329 ILE A N 1 ATOM 2313 C CA . ILE A 1 305 ? 44.471 89.584 53.357 1.00 50.73 ? 329 ILE A CA 1 ATOM 2314 C C . ILE A 1 305 ? 44.654 88.156 52.885 1.00 50.71 ? 329 ILE A C 1 ATOM 2315 O O . ILE A 1 305 ? 45.657 87.822 52.274 1.00 49.27 ? 329 ILE A O 1 ATOM 2316 C CB . ILE A 1 305 ? 44.220 90.516 52.132 1.00 58.24 ? 329 ILE A CB 1 ATOM 2317 C CG1 . ILE A 1 305 ? 44.001 91.955 52.613 1.00 60.36 ? 329 ILE A CG1 1 ATOM 2318 C CG2 . ILE A 1 305 ? 43.016 90.012 51.320 1.00 55.83 ? 329 ILE A CG2 1 ATOM 2319 C CD1 . ILE A 1 305 ? 44.073 93.014 51.520 1.00 74.54 ? 329 ILE A CD1 1 ATOM 2320 N N . SER A 1 306 ? 43.680 87.313 53.189 1.00 52.43 ? 330 SER A N 1 ATOM 2321 C CA . SER A 1 306 ? 43.724 85.929 52.765 1.00 53.60 ? 330 SER A CA 1 ATOM 2322 C C . SER A 1 306 ? 42.858 85.785 51.522 1.00 52.19 ? 330 SER A C 1 ATOM 2323 O O . SER A 1 306 ? 41.672 86.132 51.523 1.00 54.06 ? 330 SER A O 1 ATOM 2324 C CB . SER A 1 306 ? 43.221 85.030 53.890 1.00 52.12 ? 330 SER A CB 1 ATOM 2325 O OG . SER A 1 306 ? 43.876 85.379 55.103 1.00 56.95 ? 330 SER A OG 1 ATOM 2326 N N . VAL A 1 307 ? 43.453 85.280 50.452 1.00 48.67 ? 331 VAL A N 1 ATOM 2327 C CA . VAL A 1 307 ? 42.720 85.141 49.218 1.00 44.26 ? 331 VAL A CA 1 ATOM 2328 C C . VAL A 1 307 ? 42.558 83.693 48.826 1.00 44.75 ? 331 VAL A C 1 ATOM 2329 O O . VAL A 1 307 ? 43.538 83.005 48.562 1.00 45.59 ? 331 VAL A O 1 ATOM 2330 C CB . VAL A 1 307 ? 43.434 85.913 48.049 1.00 40.16 ? 331 VAL A CB 1 ATOM 2331 C CG1 . VAL A 1 307 ? 42.766 85.599 46.724 1.00 39.74 ? 331 VAL A CG1 1 ATOM 2332 C CG2 . VAL A 1 307 ? 43.406 87.418 48.296 1.00 36.20 ? 331 VAL A CG2 1 ATOM 2333 N N . ARG A 1 308 ? 41.326 83.214 48.852 1.00 48.53 ? 332 ARG A N 1 ATOM 2334 C CA . ARG A 1 308 ? 41.074 81.874 48.360 1.00 51.61 ? 332 ARG A CA 1 ATOM 2335 C C . ARG A 1 308 ? 40.372 82.021 46.991 1.00 51.84 ? 332 ARG A C 1 ATOM 2336 O O . ARG A 1 308 ? 39.527 82.909 46.789 1.00 53.82 ? 332 ARG A O 1 ATOM 2337 C CB . ARG A 1 308 ? 40.249 81.013 49.342 1.00 49.86 ? 332 ARG A CB 1 ATOM 2338 C CG . ARG A 1 308 ? 39.162 81.760 50.096 1.00 54.18 ? 332 ARG A CG 1 ATOM 2339 C CD . ARG A 1 308 ? 38.147 80.803 50.773 1.00 55.95 ? 332 ARG A CD 1 ATOM 2340 N NE . ARG A 1 308 ? 36.878 81.468 51.094 1.00 56.25 ? 332 ARG A NE 1 ATOM 2341 C CZ . ARG A 1 308 ? 36.761 82.678 51.648 1.00 56.28 ? 332 ARG A CZ 1 ATOM 2342 N NH1 . ARG A 1 308 ? 37.836 83.395 51.962 1.00 56.32 ? 332 ARG A NH1 1 ATOM 2343 N NH2 . ARG A 1 308 ? 35.554 83.184 51.885 1.00 56.91 ? 332 ARG A NH2 1 ATOM 2344 N N . VAL A 1 309 ? 40.767 81.158 46.057 1.00 46.56 ? 333 VAL A N 1 ATOM 2345 C CA . VAL A 1 309 ? 40.257 81.181 44.703 1.00 42.29 ? 333 VAL A CA 1 ATOM 2346 C C . VAL A 1 309 ? 39.346 80.002 44.424 1.00 44.63 ? 333 VAL A C 1 ATOM 2347 O O . VAL A 1 309 ? 39.788 78.847 44.358 1.00 44.89 ? 333 VAL A O 1 ATOM 2348 C CB . VAL A 1 309 ? 41.446 81.172 43.671 1.00 37.54 ? 333 VAL A CB 1 ATOM 2349 C CG1 . VAL A 1 309 ? 40.929 80.901 42.252 1.00 32.72 ? 333 VAL A CG1 1 ATOM 2350 C CG2 . VAL A 1 309 ? 42.194 82.480 43.729 1.00 30.04 ? 333 VAL A CG2 1 ATOM 2351 N N . LYS A 1 310 ? 38.060 80.295 44.299 1.00 49.95 ? 334 LYS A N 1 ATOM 2352 C CA . LYS A 1 310 ? 37.082 79.270 43.932 1.00 55.50 ? 334 LYS A CA 1 ATOM 2353 C C . LYS A 1 310 ? 36.792 79.452 42.423 1.00 55.60 ? 334 LYS A C 1 ATOM 2354 O O . LYS A 1 310 ? 37.191 80.458 41.828 1.00 56.73 ? 334 LYS A O 1 ATOM 2355 C CB . LYS A 1 310 ? 35.802 79.400 44.772 1.00 68.84 ? 334 LYS A CB 1 ATOM 2356 C CG . LYS A 1 310 ? 35.986 79.131 46.271 1.00 74.18 ? 334 LYS A CG 1 ATOM 2357 C CD . LYS A 1 310 ? 36.361 77.673 46.579 1.00 77.53 ? 334 LYS A CD 1 ATOM 2358 C CE . LYS A 1 310 ? 36.306 77.361 48.093 1.00 79.74 ? 334 LYS A CE 1 ATOM 2359 N NZ . LYS A 1 310 ? 34.934 76.973 48.593 1.00 79.53 ? 334 LYS A NZ 1 ATOM 2360 N N . ALA A 1 311 ? 36.109 78.495 41.808 1.00 56.97 ? 335 ALA A N 1 ATOM 2361 C CA . ALA A 1 311 ? 35.856 78.571 40.377 1.00 54.96 ? 335 ALA A CA 1 ATOM 2362 C C . ALA A 1 311 ? 34.492 78.101 39.903 1.00 54.28 ? 335 ALA A C 1 ATOM 2363 O O . ALA A 1 311 ? 34.005 77.058 40.332 1.00 55.85 ? 335 ALA A O 1 ATOM 2364 C CB . ALA A 1 311 ? 36.918 77.746 39.630 1.00 41.07 ? 335 ALA A CB 1 ATOM 2365 N N . ALA A 1 312 ? 33.876 78.902 39.037 1.00 49.78 ? 336 ALA A N 1 ATOM 2366 C CA . ALA A 1 312 ? 32.644 78.491 38.355 1.00 48.63 ? 336 ALA A CA 1 ATOM 2367 C C . ALA A 1 312 ? 33.105 77.413 37.352 1.00 47.12 ? 336 ALA A C 1 ATOM 2368 O O . ALA A 1 312 ? 34.242 77.448 36.863 1.00 51.22 ? 336 ALA A O 1 ATOM 2369 C CB . ALA A 1 312 ? 32.029 79.659 37.604 1.00 41.72 ? 336 ALA A CB 1 ATOM 2370 N N . PRO A 1 313 ? 32.221 76.462 37.020 1.00 44.61 ? 337 PRO A N 1 ATOM 2371 C CA . PRO A 1 313 ? 32.596 75.405 36.086 1.00 44.61 ? 337 PRO A CA 1 ATOM 2372 C C . PRO A 1 313 ? 33.028 75.916 34.721 1.00 46.01 ? 337 PRO A C 1 ATOM 2373 O O . PRO A 1 313 ? 32.469 76.886 34.209 1.00 45.49 ? 337 PRO A O 1 ATOM 2374 C CB . PRO A 1 313 ? 31.318 74.557 35.968 1.00 41.80 ? 337 PRO A CB 1 ATOM 2375 C CG . PRO A 1 313 ? 30.534 74.894 37.157 1.00 39.86 ? 337 PRO A CG 1 ATOM 2376 C CD . PRO A 1 313 ? 30.802 76.350 37.392 1.00 41.47 ? 337 PRO A CD 1 ATOM 2377 N N . TYR A 1 314 ? 34.041 75.260 34.156 1.00 56.00 ? 338 TYR A N 1 ATOM 2378 C CA . TYR A 1 314 ? 34.523 75.540 32.807 1.00 59.41 ? 338 TYR A CA 1 ATOM 2379 C C . TYR A 1 314 ? 34.807 74.190 32.175 1.00 58.26 ? 338 TYR A C 1 ATOM 2380 O O . TYR A 1 314 ? 35.267 73.269 32.846 1.00 60.05 ? 338 TYR A O 1 ATOM 2381 C CB . TYR A 1 314 ? 35.734 76.464 32.788 1.00 63.79 ? 338 TYR A CB 1 ATOM 2382 C CG . TYR A 1 314 ? 36.907 76.070 33.655 1.00 69.08 ? 338 TYR A CG 1 ATOM 2383 C CD1 . TYR A 1 314 ? 38.055 75.498 33.097 1.00 73.14 ? 338 TYR A CD1 1 ATOM 2384 C CD2 . TYR A 1 314 ? 36.895 76.297 35.031 1.00 71.17 ? 338 TYR A CD2 1 ATOM 2385 C CE1 . TYR A 1 314 ? 39.168 75.163 33.892 1.00 73.75 ? 338 TYR A CE1 1 ATOM 2386 C CE2 . TYR A 1 314 ? 37.995 75.965 35.833 1.00 72.42 ? 338 TYR A CE2 1 ATOM 2387 C CZ . TYR A 1 314 ? 39.126 75.400 35.260 1.00 73.46 ? 338 TYR A CZ 1 ATOM 2388 O OH . TYR A 1 314 ? 40.206 75.067 36.050 1.00 73.10 ? 338 TYR A OH 1 ATOM 2389 N N . TRP A 1 315 ? 34.525 74.086 30.881 1.00 53.81 ? 339 TRP A N 1 ATOM 2390 C CA . TRP A 1 315 ? 34.617 72.827 30.195 1.00 54.25 ? 339 TRP A CA 1 ATOM 2391 C C . TRP A 1 315 ? 35.977 72.187 30.089 1.00 55.14 ? 339 TRP A C 1 ATOM 2392 O O . TRP A 1 315 ? 36.953 72.848 29.714 1.00 56.40 ? 339 TRP A O 1 ATOM 2393 C CB . TRP A 1 315 ? 34.074 72.957 28.765 1.00 52.77 ? 339 TRP A CB 1 ATOM 2394 C CG . TRP A 1 315 ? 32.587 73.127 28.640 1.00 49.65 ? 339 TRP A CG 1 ATOM 2395 C CD1 . TRP A 1 315 ? 31.919 74.218 28.143 1.00 48.27 ? 339 TRP A CD1 1 ATOM 2396 C CD2 . TRP A 1 315 ? 31.586 72.172 28.996 1.00 47.95 ? 339 TRP A CD2 1 ATOM 2397 N NE1 . TRP A 1 315 ? 30.571 73.992 28.167 1.00 47.71 ? 339 TRP A NE1 1 ATOM 2398 C CE2 . TRP A 1 315 ? 30.335 72.746 28.687 1.00 46.95 ? 339 TRP A CE2 1 ATOM 2399 C CE3 . TRP A 1 315 ? 31.623 70.887 29.546 1.00 46.86 ? 339 TRP A CE3 1 ATOM 2400 C CZ2 . TRP A 1 315 ? 29.126 72.076 28.916 1.00 47.31 ? 339 TRP A CZ2 1 ATOM 2401 C CZ3 . TRP A 1 315 ? 30.416 70.223 29.770 1.00 46.79 ? 339 TRP A CZ3 1 ATOM 2402 C CH2 . TRP A 1 315 ? 29.186 70.820 29.456 1.00 45.12 ? 339 TRP A CH2 1 ATOM 2403 N N . LEU A 1 316 ? 36.032 70.922 30.502 1.00 61.13 ? 340 LEU A N 1 ATOM 2404 C CA . LEU A 1 316 ? 37.185 70.093 30.226 1.00 64.49 ? 340 LEU A CA 1 ATOM 2405 C C . LEU A 1 316 ? 36.748 69.264 28.999 1.00 66.94 ? 340 LEU A C 1 ATOM 2406 O O . LEU A 1 316 ? 37.365 69.335 27.932 1.00 69.83 ? 340 LEU A O 1 ATOM 2407 C CB . LEU A 1 316 ? 37.519 69.135 31.369 1.00 62.11 ? 340 LEU A CB 1 ATOM 2408 C CG . LEU A 1 316 ? 38.813 69.392 32.161 1.00 60.14 ? 340 LEU A CG 1 ATOM 2409 C CD1 . LEU A 1 316 ? 39.190 70.878 32.178 1.00 59.45 ? 340 LEU A CD1 1 ATOM 2410 C CD2 . LEU A 1 316 ? 38.645 68.861 33.586 1.00 57.16 ? 340 LEU A CD2 1 ATOM 2411 N N . ASP A 1 317 ? 35.656 68.518 29.157 1.00 71.05 ? 341 ASP A N 1 ATOM 2412 C CA . ASP A 1 317 ? 35.176 67.626 28.116 1.00 71.41 ? 341 ASP A CA 1 ATOM 2413 C C . ASP A 1 317 ? 33.708 67.840 27.801 1.00 67.27 ? 341 ASP A C 1 ATOM 2414 O O . ASP A 1 317 ? 32.847 67.133 28.323 1.00 62.26 ? 341 ASP A O 1 ATOM 2415 C CB . ASP A 1 317 ? 35.417 66.176 28.560 1.00 87.23 ? 341 ASP A CB 1 ATOM 2416 C CG . ASP A 1 317 ? 36.070 65.332 27.479 1.00 98.84 ? 341 ASP A CG 1 ATOM 2417 O OD1 . ASP A 1 317 ? 36.724 64.323 27.831 1.00 104.61 ? 341 ASP A OD1 1 ATOM 2418 O OD2 . ASP A 1 317 ? 35.930 65.677 26.283 1.00 104.25 ? 341 ASP A OD2 1 ATOM 2419 N N . GLU A 1 318 ? 33.435 68.822 26.943 1.00 59.00 ? 342 GLU A N 1 ATOM 2420 C CA . GLU A 1 318 ? 32.066 69.135 26.526 1.00 60.34 ? 342 GLU A CA 1 ATOM 2421 C C . GLU A 1 318 ? 31.514 68.069 25.586 1.00 61.76 ? 342 GLU A C 1 ATOM 2422 O O . GLU A 1 318 ? 32.192 67.647 24.648 1.00 57.72 ? 342 GLU A O 1 ATOM 2423 C CB . GLU A 1 318 ? 32.024 70.509 25.828 1.00 63.61 ? 342 GLU A CB 1 ATOM 2424 C CG . GLU A 1 318 ? 30.667 70.882 25.222 1.00 69.74 ? 342 GLU A CG 1 ATOM 2425 C CD . GLU A 1 318 ? 30.557 72.359 24.828 1.00 72.54 ? 342 GLU A CD 1 ATOM 2426 O OE1 . GLU A 1 318 ? 31.572 73.086 24.883 1.00 73.42 ? 342 GLU A OE1 1 ATOM 2427 O OE2 . GLU A 1 318 ? 29.444 72.789 24.456 1.00 74.07 ? 342 GLU A OE2 1 ATOM 2428 N N . PRO A 1 319 ? 30.293 67.583 25.855 1.00 70.08 ? 343 PRO A N 1 ATOM 2429 C CA . PRO A 1 319 ? 29.717 66.567 24.968 1.00 74.30 ? 343 PRO A CA 1 ATOM 2430 C C . PRO A 1 319 ? 29.347 67.172 23.610 1.00 79.95 ? 343 PRO A C 1 ATOM 2431 O O . PRO A 1 319 ? 28.787 68.271 23.543 1.00 81.64 ? 343 PRO A O 1 ATOM 2432 C CB . PRO A 1 319 ? 28.468 66.088 25.718 1.00 62.04 ? 343 PRO A CB 1 ATOM 2433 C CG . PRO A 1 319 ? 28.146 67.171 26.652 1.00 58.15 ? 343 PRO A CG 1 ATOM 2434 C CD . PRO A 1 319 ? 29.468 67.775 27.059 1.00 59.34 ? 343 PRO A CD 1 ATOM 2435 N N . LYS A 1 320 ? 29.684 66.450 22.541 1.00 78.52 ? 344 LYS A N 1 ATOM 2436 C CA . LYS A 1 320 ? 29.351 66.863 21.178 1.00 81.68 ? 344 LYS A CA 1 ATOM 2437 C C . LYS A 1 320 ? 28.280 65.899 20.649 1.00 80.91 ? 344 LYS A C 1 ATOM 2438 O O . LYS A 1 320 ? 28.060 64.824 21.225 1.00 78.88 ? 344 LYS A O 1 ATOM 2439 C CB . LYS A 1 320 ? 30.586 66.787 20.261 1.00 95.24 ? 344 LYS A CB 1 ATOM 2440 C CG . LYS A 1 320 ? 31.849 67.450 20.805 1.00 100.86 ? 344 LYS A CG 1 ATOM 2441 C CD . LYS A 1 320 ? 33.097 66.889 20.116 1.00 103.50 ? 344 LYS A CD 1 ATOM 2442 C CE . LYS A 1 320 ? 34.353 67.100 20.962 1.00 103.43 ? 344 LYS A CE 1 ATOM 2443 N NZ . LYS A 1 320 ? 35.394 66.062 20.680 1.00 102.50 ? 344 LYS A NZ 1 ATOM 2444 N N . ASN A 1 321 ? 27.625 66.301 19.557 1.00 84.93 ? 345 ASN A N 1 ATOM 2445 C CA . ASN A 1 321 ? 26.606 65.476 18.900 1.00 82.25 ? 345 ASN A CA 1 ATOM 2446 C C . ASN A 1 321 ? 27.189 64.124 18.474 1.00 78.63 ? 345 ASN A C 1 ATOM 2447 O O . ASN A 1 321 ? 28.386 64.000 18.205 1.00 75.53 ? 345 ASN A O 1 ATOM 2448 C CB . ASN A 1 321 ? 26.056 66.187 17.663 1.00 98.03 ? 345 ASN A CB 1 ATOM 2449 C CG . ASN A 1 321 ? 25.549 67.590 17.965 1.00 106.99 ? 345 ASN A CG 1 ATOM 2450 O OD1 . ASN A 1 321 ? 25.833 68.531 17.223 1.00 112.01 ? 345 ASN A OD1 1 ATOM 2451 N ND2 . ASN A 1 321 ? 24.786 67.734 19.046 1.00 111.42 ? 345 ASN A ND2 1 ATOM 2452 N N . LEU A 1 322 ? 26.326 63.118 18.417 1.00 77.18 ? 346 LEU A N 1 ATOM 2453 C CA . LEU A 1 322 ? 26.745 61.790 18.038 1.00 74.46 ? 346 LEU A CA 1 ATOM 2454 C C . LEU A 1 322 ? 26.045 61.244 16.795 1.00 75.65 ? 346 LEU A C 1 ATOM 2455 O O . LEU A 1 322 ? 24.824 61.076 16.778 1.00 80.81 ? 346 LEU A O 1 ATOM 2456 C CB . LEU A 1 322 ? 26.532 60.799 19.199 1.00 56.00 ? 346 LEU A CB 1 ATOM 2457 C CG . LEU A 1 322 ? 27.521 60.807 20.379 1.00 48.41 ? 346 LEU A CG 1 ATOM 2458 C CD1 . LEU A 1 322 ? 27.163 59.679 21.347 1.00 43.14 ? 346 LEU A CD1 1 ATOM 2459 C CD2 . LEU A 1 322 ? 28.959 60.649 19.900 1.00 45.70 ? 346 LEU A CD2 1 ATOM 2460 N N . ILE A 1 323 ? 26.827 60.996 15.745 1.00 73.93 ? 347 ILE A N 1 ATOM 2461 C CA . ILE A 1 323 ? 26.294 60.349 14.540 1.00 75.37 ? 347 ILE A CA 1 ATOM 2462 C C . ILE A 1 323 ? 26.928 58.951 14.450 1.00 71.16 ? 347 ILE A C 1 ATOM 2463 O O . ILE A 1 323 ? 28.114 58.797 14.155 1.00 71.40 ? 347 ILE A O 1 ATOM 2464 C CB . ILE A 1 323 ? 26.564 61.159 13.265 1.00 74.59 ? 347 ILE A CB 1 ATOM 2465 C CG1 . ILE A 1 323 ? 25.920 62.551 13.390 1.00 77.38 ? 347 ILE A CG1 1 ATOM 2466 C CG2 . ILE A 1 323 ? 26.002 60.409 12.055 1.00 76.45 ? 347 ILE A CG2 1 ATOM 2467 C CD1 . ILE A 1 323 ? 26.692 63.536 14.259 1.00 82.87 ? 347 ILE A CD1 1 ATOM 2468 N N . LEU A 1 324 ? 26.117 57.937 14.712 1.00 73.94 ? 348 LEU A N 1 ATOM 2469 C CA . LEU A 1 324 ? 26.607 56.575 14.748 1.00 76.37 ? 348 LEU A CA 1 ATOM 2470 C C . LEU A 1 324 ? 25.954 55.666 13.722 1.00 80.61 ? 348 LEU A C 1 ATOM 2471 O O . LEU A 1 324 ? 24.839 55.923 13.270 1.00 78.27 ? 348 LEU A O 1 ATOM 2472 C CB . LEU A 1 324 ? 26.379 55.990 16.159 1.00 73.21 ? 348 LEU A CB 1 ATOM 2473 C CG . LEU A 1 324 ? 27.028 56.744 17.333 1.00 70.99 ? 348 LEU A CG 1 ATOM 2474 C CD1 . LEU A 1 324 ? 26.418 56.295 18.649 1.00 68.77 ? 348 LEU A CD1 1 ATOM 2475 C CD2 . LEU A 1 324 ? 28.539 56.545 17.337 1.00 69.20 ? 348 LEU A CD2 1 ATOM 2476 N N . ALA A 1 325 ? 26.677 54.616 13.342 1.00 86.65 ? 349 ALA A N 1 ATOM 2477 C CA . ALA A 1 325 ? 26.136 53.609 12.442 1.00 93.73 ? 349 ALA A CA 1 ATOM 2478 C C . ALA A 1 325 ? 25.437 52.566 13.322 1.00 93.95 ? 349 ALA A C 1 ATOM 2479 O O . ALA A 1 325 ? 25.923 52.233 14.408 1.00 97.20 ? 349 ALA A O 1 ATOM 2480 C CB . ALA A 1 325 ? 27.244 52.967 11.637 1.00 97.32 ? 349 ALA A CB 1 ATOM 2481 N N . PRO A 1 326 ? 24.282 52.047 12.865 1.00 92.85 ? 350 PRO A N 1 ATOM 2482 C CA . PRO A 1 326 ? 23.532 51.045 13.636 1.00 91.60 ? 350 PRO A CA 1 ATOM 2483 C C . PRO A 1 326 ? 24.388 49.888 14.137 1.00 91.80 ? 350 PRO A C 1 ATOM 2484 O O . PRO A 1 326 ? 24.969 49.155 13.337 1.00 95.61 ? 350 PRO A O 1 ATOM 2485 C CB . PRO A 1 326 ? 22.431 50.583 12.668 1.00 79.43 ? 350 PRO A CB 1 ATOM 2486 C CG . PRO A 1 326 ? 22.798 51.177 11.322 1.00 76.91 ? 350 PRO A CG 1 ATOM 2487 C CD . PRO A 1 326 ? 23.580 52.411 11.623 1.00 79.54 ? 350 PRO A CD 1 ATOM 2488 N N . GLY A 1 327 ? 24.461 49.739 15.462 1.00 87.91 ? 351 GLY A N 1 ATOM 2489 C CA . GLY A 1 327 ? 25.237 48.673 16.080 1.00 81.23 ? 351 GLY A CA 1 ATOM 2490 C C . GLY A 1 327 ? 26.501 49.174 16.756 1.00 79.33 ? 351 GLY A C 1 ATOM 2491 O O . GLY A 1 327 ? 27.105 48.473 17.572 1.00 77.74 ? 351 GLY A O 1 ATOM 2492 N N . GLU A 1 328 ? 26.896 50.399 16.429 1.00 74.60 ? 352 GLU A N 1 ATOM 2493 C CA . GLU A 1 328 ? 28.119 50.976 16.967 1.00 75.80 ? 352 GLU A CA 1 ATOM 2494 C C . GLU A 1 328 ? 27.961 51.505 18.383 1.00 80.28 ? 352 GLU A C 1 ATOM 2495 O O . GLU A 1 328 ? 26.943 52.121 18.714 1.00 79.73 ? 352 GLU A O 1 ATOM 2496 C CB . GLU A 1 328 ? 28.598 52.119 16.055 1.00 73.39 ? 352 GLU A CB 1 ATOM 2497 C CG . GLU A 1 328 ? 30.049 52.520 16.259 1.00 70.11 ? 352 GLU A CG 1 ATOM 2498 C CD . GLU A 1 328 ? 30.373 53.871 15.657 1.00 70.05 ? 352 GLU A CD 1 ATOM 2499 O OE1 . GLU A 1 328 ? 29.630 54.344 14.764 1.00 67.94 ? 352 GLU A OE1 1 ATOM 2500 O OE2 . GLU A 1 328 ? 31.386 54.462 16.082 1.00 70.59 ? 352 GLU A OE2 1 ATOM 2501 N N . ASP A 1 329 ? 28.967 51.248 19.217 1.00 77.05 ? 353 ASP A N 1 ATOM 2502 C CA . ASP A 1 329 ? 28.984 51.765 20.587 1.00 79.28 ? 353 ASP A CA 1 ATOM 2503 C C . ASP A 1 329 ? 29.412 53.246 20.579 1.00 73.81 ? 353 ASP A C 1 ATOM 2504 O O . ASP A 1 329 ? 30.416 53.618 19.959 1.00 67.36 ? 353 ASP A O 1 ATOM 2505 C CB . ASP A 1 329 ? 29.962 50.968 21.461 1.00 99.06 ? 353 ASP A CB 1 ATOM 2506 C CG . ASP A 1 329 ? 29.677 49.473 21.450 1.00 118.23 ? 353 ASP A CG 1 ATOM 2507 O OD1 . ASP A 1 329 ? 30.000 48.803 20.437 1.00 128.24 ? 353 ASP A OD1 1 ATOM 2508 O OD2 . ASP A 1 329 ? 29.131 48.967 22.458 1.00 127.79 ? 353 ASP A OD2 1 ATOM 2509 N N . GLY A 1 330 ? 28.628 54.084 21.256 1.00 73.29 ? 354 GLY A N 1 ATOM 2510 C CA . GLY A 1 330 ? 28.937 55.504 21.357 1.00 71.12 ? 354 GLY A CA 1 ATOM 2511 C C . GLY A 1 330 ? 29.076 55.937 22.810 1.00 70.76 ? 354 GLY A C 1 ATOM 2512 O O . GLY A 1 330 ? 28.741 55.178 23.724 1.00 70.29 ? 354 GLY A O 1 ATOM 2513 N N . ARG A 1 331 ? 29.576 57.150 23.033 1.00 75.99 ? 355 ARG A N 1 ATOM 2514 C CA . ARG A 1 331 ? 29.728 57.654 24.392 1.00 75.77 ? 355 ARG A CA 1 ATOM 2515 C C . ARG A 1 331 ? 29.658 59.171 24.501 1.00 72.46 ? 355 ARG A C 1 ATOM 2516 O O . ARG A 1 331 ? 30.058 59.903 23.586 1.00 72.84 ? 355 ARG A O 1 ATOM 2517 C CB . ARG A 1 331 ? 31.052 57.146 25.022 1.00 79.42 ? 355 ARG A CB 1 ATOM 2518 C CG . ARG A 1 331 ? 32.233 58.132 25.078 1.00 81.59 ? 355 ARG A CG 1 ATOM 2519 C CD . ARG A 1 331 ? 33.030 58.183 23.784 1.00 80.82 ? 355 ARG A CD 1 ATOM 2520 N NE . ARG A 1 331 ? 32.811 59.412 23.029 1.00 82.00 ? 355 ARG A NE 1 ATOM 2521 C CZ . ARG A 1 331 ? 33.516 60.530 23.179 1.00 81.79 ? 355 ARG A CZ 1 ATOM 2522 N NH1 . ARG A 1 331 ? 34.497 60.580 24.064 1.00 82.30 ? 355 ARG A NH1 1 ATOM 2523 N NH2 . ARG A 1 331 ? 33.240 61.600 22.441 1.00 81.63 ? 355 ARG A NH2 1 ATOM 2524 N N . LEU A 1 332 ? 29.103 59.624 25.623 1.00 64.39 ? 356 LEU A N 1 ATOM 2525 C CA . LEU A 1 332 ? 29.041 61.043 25.933 1.00 60.36 ? 356 LEU A CA 1 ATOM 2526 C C . LEU A 1 332 ? 29.741 61.286 27.266 1.00 59.25 ? 356 LEU A C 1 ATOM 2527 O O . LEU A 1 332 ? 29.422 60.665 28.277 1.00 57.20 ? 356 LEU A O 1 ATOM 2528 C CB . LEU A 1 332 ? 27.599 61.543 26.003 1.00 57.71 ? 356 LEU A CB 1 ATOM 2529 C CG . LEU A 1 332 ? 26.825 61.586 24.674 1.00 56.57 ? 356 LEU A CG 1 ATOM 2530 C CD1 . LEU A 1 332 ? 25.346 61.830 24.945 1.00 55.35 ? 356 LEU A CD1 1 ATOM 2531 C CD2 . LEU A 1 332 ? 27.394 62.662 23.752 1.00 55.64 ? 356 LEU A CD2 1 ATOM 2532 N N . VAL A 1 333 ? 30.735 62.163 27.235 1.00 62.26 ? 357 VAL A N 1 ATOM 2533 C CA . VAL A 1 333 ? 31.470 62.529 28.425 1.00 65.55 ? 357 VAL A CA 1 ATOM 2534 C C . VAL A 1 333 ? 31.215 64.006 28.664 1.00 64.13 ? 357 VAL A C 1 ATOM 2535 O O . VAL A 1 333 ? 31.408 64.840 27.778 1.00 63.16 ? 357 VAL A O 1 ATOM 2536 C CB . VAL A 1 333 ? 33.001 62.284 28.274 1.00 73.83 ? 357 VAL A CB 1 ATOM 2537 C CG1 . VAL A 1 333 ? 33.757 62.827 29.492 1.00 77.52 ? 357 VAL A CG1 1 ATOM 2538 C CG2 . VAL A 1 333 ? 33.273 60.793 28.097 1.00 78.09 ? 357 VAL A CG2 1 ATOM 2539 N N . CYS A 1 334 ? 30.751 64.310 29.870 1.00 69.57 ? 358 CYS A N 1 ATOM 2540 C CA . CYS A 1 334 ? 30.466 65.673 30.270 1.00 70.19 ? 358 CYS A CA 1 ATOM 2541 C C . CYS A 1 334 ? 31.228 65.952 31.548 1.00 68.22 ? 358 CYS A C 1 ATOM 2542 O O . CYS A 1 334 ? 30.783 65.611 32.640 1.00 69.16 ? 358 CYS A O 1 ATOM 2543 C CB . CYS A 1 334 ? 28.978 65.835 30.494 1.00 72.69 ? 358 CYS A CB 1 ATOM 2544 S SG . CYS A 1 334 ? 28.517 67.471 31.121 1.00 76.68 ? 358 CYS A SG 1 ATOM 2545 N N . ARG A 1 335 ? 32.383 66.581 31.397 1.00 55.91 ? 359 ARG A N 1 ATOM 2546 C CA . ARG A 1 335 ? 33.235 66.856 32.522 1.00 51.78 ? 359 ARG A CA 1 ATOM 2547 C C . ARG A 1 335 ? 33.722 68.281 32.521 1.00 48.99 ? 359 ARG A C 1 ATOM 2548 O O . ARG A 1 335 ? 34.279 68.759 31.539 1.00 46.05 ? 359 ARG A O 1 ATOM 2549 C CB . ARG A 1 335 ? 34.438 65.890 32.515 1.00 62.64 ? 359 ARG A CB 1 ATOM 2550 C CG . ARG A 1 335 ? 34.122 64.509 33.095 1.00 71.64 ? 359 ARG A CG 1 ATOM 2551 C CD . ARG A 1 335 ? 35.340 63.572 33.138 1.00 76.13 ? 359 ARG A CD 1 ATOM 2552 N NE . ARG A 1 335 ? 36.510 64.134 33.826 1.00 78.32 ? 359 ARG A NE 1 ATOM 2553 C CZ . ARG A 1 335 ? 36.606 64.335 35.142 1.00 79.17 ? 359 ARG A CZ 1 ATOM 2554 N NH1 . ARG A 1 335 ? 35.597 64.022 35.953 1.00 79.18 ? 359 ARG A NH1 1 ATOM 2555 N NH2 . ARG A 1 335 ? 37.722 64.852 35.654 1.00 79.72 ? 359 ARG A NH2 1 ATOM 2556 N N . ALA A 1 336 ? 33.476 68.971 33.625 1.00 51.53 ? 360 ALA A N 1 ATOM 2557 C CA . ALA A 1 336 ? 33.949 70.328 33.785 1.00 52.72 ? 360 ALA A CA 1 ATOM 2558 C C . ALA A 1 336 ? 34.776 70.409 35.054 1.00 54.33 ? 360 ALA A C 1 ATOM 2559 O O . ALA A 1 336 ? 34.512 69.696 36.016 1.00 55.50 ? 360 ALA A O 1 ATOM 2560 C CB . ALA A 1 336 ? 32.775 71.296 33.896 1.00 48.72 ? 360 ALA A CB 1 ATOM 2561 N N . ASN A 1 337 ? 35.790 71.258 35.042 1.00 54.83 ? 361 ASN A N 1 ATOM 2562 C CA . ASN A 1 337 ? 36.572 71.488 36.241 1.00 60.13 ? 361 ASN A CA 1 ATOM 2563 C C . ASN A 1 337 ? 36.026 72.737 36.933 1.00 61.26 ? 361 ASN A C 1 ATOM 2564 O O . ASN A 1 337 ? 35.724 73.736 36.292 1.00 60.05 ? 361 ASN A O 1 ATOM 2565 C CB . ASN A 1 337 ? 38.059 71.693 35.926 1.00 76.19 ? 361 ASN A CB 1 ATOM 2566 C CG . ASN A 1 337 ? 38.928 71.687 37.184 1.00 84.76 ? 361 ASN A CG 1 ATOM 2567 O OD1 . ASN A 1 337 ? 38.568 71.082 38.205 1.00 87.40 ? 361 ASN A OD1 1 ATOM 2568 N ND2 . ASN A 1 337 ? 40.088 72.343 37.108 1.00 89.00 ? 361 ASN A ND2 1 ATOM 2569 N N . GLY A 1 338 ? 35.891 72.651 38.251 1.00 69.93 ? 362 GLY A N 1 ATOM 2570 C CA . GLY A 1 338 ? 35.427 73.767 39.051 1.00 70.05 ? 362 GLY A CA 1 ATOM 2571 C C . GLY A 1 338 ? 35.844 73.592 40.498 1.00 68.71 ? 362 GLY A C 1 ATOM 2572 O O . GLY A 1 338 ? 36.398 72.567 40.876 1.00 71.08 ? 362 GLY A O 1 ATOM 2573 N N . ASN A 1 339 ? 35.577 74.606 41.307 1.00 58.60 ? 363 ASN A N 1 ATOM 2574 C CA . ASN A 1 339 ? 35.890 74.566 42.709 1.00 54.40 ? 363 ASN A CA 1 ATOM 2575 C C . ASN A 1 339 ? 34.835 75.347 43.490 1.00 52.44 ? 363 ASN A C 1 ATOM 2576 O O . ASN A 1 339 ? 34.790 76.575 43.429 1.00 51.25 ? 363 ASN A O 1 ATOM 2577 C CB . ASN A 1 339 ? 37.285 75.170 42.966 1.00 55.18 ? 363 ASN A CB 1 ATOM 2578 C CG . ASN A 1 339 ? 37.775 74.935 44.391 1.00 54.91 ? 363 ASN A CG 1 ATOM 2579 O OD1 . ASN A 1 339 ? 37.111 74.257 45.185 1.00 53.86 ? 363 ASN A OD1 1 ATOM 2580 N ND2 . ASN A 1 339 ? 38.932 75.503 44.721 1.00 54.23 ? 363 ASN A ND2 1 ATOM 2581 N N . PRO A 1 340 ? 33.930 74.627 44.192 1.00 49.56 ? 364 PRO A N 1 ATOM 2582 C CA . PRO A 1 340 ? 33.858 73.170 44.410 1.00 50.09 ? 364 PRO A CA 1 ATOM 2583 C C . PRO A 1 340 ? 33.687 72.382 43.121 1.00 52.50 ? 364 PRO A C 1 ATOM 2584 O O . PRO A 1 340 ? 33.241 72.935 42.129 1.00 54.29 ? 364 PRO A O 1 ATOM 2585 C CB . PRO A 1 340 ? 32.607 73.006 45.283 1.00 41.61 ? 364 PRO A CB 1 ATOM 2586 C CG . PRO A 1 340 ? 32.446 74.307 45.954 1.00 40.90 ? 364 PRO A CG 1 ATOM 2587 C CD . PRO A 1 340 ? 32.850 75.316 44.916 1.00 43.93 ? 364 PRO A CD 1 ATOM 2588 N N . LYS A 1 341 ? 34.005 71.087 43.162 1.00 47.40 ? 365 LYS A N 1 ATOM 2589 C CA . LYS A 1 341 ? 33.904 70.223 41.987 1.00 51.38 ? 365 LYS A CA 1 ATOM 2590 C C . LYS A 1 341 ? 32.455 70.118 41.533 1.00 46.75 ? 365 LYS A C 1 ATOM 2591 O O . LYS A 1 341 ? 31.580 69.832 42.329 1.00 44.52 ? 365 LYS A O 1 ATOM 2592 C CB . LYS A 1 341 ? 34.482 68.828 42.271 1.00 71.17 ? 365 LYS A CB 1 ATOM 2593 C CG . LYS A 1 341 ? 35.991 68.802 42.537 1.00 89.09 ? 365 LYS A CG 1 ATOM 2594 C CD . LYS A 1 341 ? 36.843 68.890 41.265 1.00 97.73 ? 365 LYS A CD 1 ATOM 2595 C CE . LYS A 1 341 ? 36.915 67.546 40.517 1.00 100.38 ? 365 LYS A CE 1 ATOM 2596 N NZ . LYS A 1 341 ? 37.722 67.643 39.261 1.00 100.42 ? 365 LYS A NZ 1 ATOM 2597 N N . PRO A 1 342 ? 32.200 70.337 40.228 1.00 49.91 ? 366 PRO A N 1 ATOM 2598 C CA . PRO A 1 342 ? 30.874 70.297 39.596 1.00 50.48 ? 366 PRO A CA 1 ATOM 2599 C C . PRO A 1 342 ? 30.085 69.015 39.738 1.00 49.55 ? 366 PRO A C 1 ATOM 2600 O O . PRO A 1 342 ? 30.653 67.961 39.926 1.00 52.74 ? 366 PRO A O 1 ATOM 2601 C CB . PRO A 1 342 ? 31.170 70.586 38.125 1.00 56.60 ? 366 PRO A CB 1 ATOM 2602 C CG . PRO A 1 342 ? 32.448 71.336 38.149 1.00 56.66 ? 366 PRO A CG 1 ATOM 2603 C CD . PRO A 1 342 ? 33.242 70.715 39.252 1.00 55.70 ? 366 PRO A CD 1 ATOM 2604 N N . THR A 1 343 ? 28.769 69.133 39.620 1.00 50.36 ? 367 THR A N 1 ATOM 2605 C CA . THR A 1 343 ? 27.845 68.006 39.660 1.00 50.69 ? 367 THR A CA 1 ATOM 2606 C C . THR A 1 343 ? 27.359 67.769 38.239 1.00 47.44 ? 367 THR A C 1 ATOM 2607 O O . THR A 1 343 ? 27.277 68.708 37.451 1.00 46.15 ? 367 THR A O 1 ATOM 2608 C CB . THR A 1 343 ? 26.555 68.337 40.448 1.00 57.85 ? 367 THR A CB 1 ATOM 2609 O OG1 . THR A 1 343 ? 26.874 69.082 41.627 1.00 65.35 ? 367 THR A OG1 1 ATOM 2610 C CG2 . THR A 1 343 ? 25.832 67.068 40.827 1.00 60.19 ? 367 THR A CG2 1 ATOM 2611 N N . VAL A 1 344 ? 26.995 66.533 37.928 1.00 44.10 ? 368 VAL A N 1 ATOM 2612 C CA . VAL A 1 344 ? 26.457 66.233 36.618 1.00 46.29 ? 368 VAL A CA 1 ATOM 2613 C C . VAL A 1 344 ? 25.030 65.701 36.710 1.00 46.57 ? 368 VAL A C 1 ATOM 2614 O O . VAL A 1 344 ? 24.759 64.768 37.466 1.00 42.74 ? 368 VAL A O 1 ATOM 2615 C CB . VAL A 1 344 ? 27.343 65.190 35.852 1.00 55.96 ? 368 VAL A CB 1 ATOM 2616 C CG1 . VAL A 1 344 ? 26.706 64.821 34.500 1.00 59.39 ? 368 VAL A CG1 1 ATOM 2617 C CG2 . VAL A 1 344 ? 28.751 65.753 35.641 1.00 58.17 ? 368 VAL A CG2 1 ATOM 2618 N N . GLN A 1 345 ? 24.126 66.338 35.960 1.00 51.94 ? 369 GLN A N 1 ATOM 2619 C CA . GLN A 1 345 ? 22.739 65.883 35.839 1.00 57.07 ? 369 GLN A CA 1 ATOM 2620 C C . GLN A 1 345 ? 22.425 65.675 34.344 1.00 56.90 ? 369 GLN A C 1 ATOM 2621 O O . GLN A 1 345 ? 22.701 66.549 33.503 1.00 58.30 ? 369 GLN A O 1 ATOM 2622 C CB . GLN A 1 345 ? 21.759 66.890 36.428 1.00 61.96 ? 369 GLN A CB 1 ATOM 2623 C CG . GLN A 1 345 ? 22.105 67.368 37.831 1.00 68.19 ? 369 GLN A CG 1 ATOM 2624 C CD . GLN A 1 345 ? 21.006 68.237 38.430 1.00 69.83 ? 369 GLN A CD 1 ATOM 2625 O OE1 . GLN A 1 345 ? 19.896 67.756 38.711 1.00 69.01 ? 369 GLN A OE1 1 ATOM 2626 N NE2 . GLN A 1 345 ? 21.305 69.523 38.622 1.00 67.26 ? 369 GLN A NE2 1 ATOM 2627 N N . TRP A 1 346 ? 21.843 64.522 34.024 1.00 55.52 ? 370 TRP A N 1 ATOM 2628 C CA . TRP A 1 346 ? 21.519 64.182 32.643 1.00 56.68 ? 370 TRP A CA 1 ATOM 2629 C C . TRP A 1 346 ? 20.030 64.290 32.332 1.00 59.78 ? 370 TRP A C 1 ATOM 2630 O O . TRP A 1 346 ? 19.186 63.941 33.154 1.00 56.28 ? 370 TRP A O 1 ATOM 2631 C CB . TRP A 1 346 ? 21.997 62.759 32.320 1.00 60.02 ? 370 TRP A CB 1 ATOM 2632 C CG . TRP A 1 346 ? 23.492 62.570 32.313 1.00 62.62 ? 370 TRP A CG 1 ATOM 2633 C CD1 . TRP A 1 346 ? 24.248 61.995 33.291 1.00 64.76 ? 370 TRP A CD1 1 ATOM 2634 C CD2 . TRP A 1 346 ? 24.404 62.950 31.274 1.00 64.38 ? 370 TRP A CD2 1 ATOM 2635 N NE1 . TRP A 1 346 ? 25.574 61.990 32.929 1.00 65.73 ? 370 TRP A NE1 1 ATOM 2636 C CE2 . TRP A 1 346 ? 25.697 62.571 31.695 1.00 65.39 ? 370 TRP A CE2 1 ATOM 2637 C CE3 . TRP A 1 346 ? 24.255 63.576 30.031 1.00 63.68 ? 370 TRP A CE3 1 ATOM 2638 C CZ2 . TRP A 1 346 ? 26.836 62.796 30.914 1.00 65.68 ? 370 TRP A CZ2 1 ATOM 2639 C CZ3 . TRP A 1 346 ? 25.385 63.798 29.258 1.00 63.95 ? 370 TRP A CZ3 1 ATOM 2640 C CH2 . TRP A 1 346 ? 26.658 63.411 29.701 1.00 64.88 ? 370 TRP A CH2 1 ATOM 2641 N N . MET A 1 347 ? 19.718 64.773 31.135 1.00 70.56 ? 371 MET A N 1 ATOM 2642 C CA . MET A 1 347 ? 18.339 64.906 30.707 1.00 74.88 ? 371 MET A CA 1 ATOM 2643 C C . MET A 1 347 ? 18.147 64.414 29.279 1.00 76.18 ? 371 MET A C 1 ATOM 2644 O O . MET A 1 347 ? 19.008 64.601 28.430 1.00 79.45 ? 371 MET A O 1 ATOM 2645 C CB . MET A 1 347 ? 17.890 66.366 30.779 1.00 74.59 ? 371 MET A CB 1 ATOM 2646 C CG . MET A 1 347 ? 17.502 66.843 32.157 1.00 75.56 ? 371 MET A CG 1 ATOM 2647 S SD . MET A 1 347 ? 16.797 68.482 32.046 1.00 78.24 ? 371 MET A SD 1 ATOM 2648 C CE . MET A 1 347 ? 16.170 68.730 33.720 1.00 78.38 ? 371 MET A CE 1 ATOM 2649 N N . VAL A 1 348 ? 17.012 63.770 29.036 1.00 63.88 ? 372 VAL A N 1 ATOM 2650 C CA . VAL A 1 348 ? 16.649 63.319 27.701 1.00 60.82 ? 372 VAL A CA 1 ATOM 2651 C C . VAL A 1 348 ? 15.448 64.160 27.267 1.00 59.47 ? 372 VAL A C 1 ATOM 2652 O O . VAL A 1 348 ? 14.323 63.940 27.727 1.00 57.25 ? 372 VAL A O 1 ATOM 2653 C CB . VAL A 1 348 ? 16.244 61.822 27.670 1.00 63.99 ? 372 VAL A CB 1 ATOM 2654 C CG1 . VAL A 1 348 ? 16.226 61.319 26.232 1.00 63.48 ? 372 VAL A CG1 1 ATOM 2655 C CG2 . VAL A 1 348 ? 17.208 60.997 28.508 1.00 64.71 ? 372 VAL A CG2 1 ATOM 2656 N N . ASN A 1 349 ? 15.713 65.127 26.391 1.00 68.46 ? 373 ASN A N 1 ATOM 2657 C CA . ASN A 1 349 ? 14.696 66.035 25.863 1.00 72.57 ? 373 ASN A CA 1 ATOM 2658 C C . ASN A 1 349 ? 13.962 66.796 26.968 1.00 75.43 ? 373 ASN A C 1 ATOM 2659 O O . ASN A 1 349 ? 12.730 66.879 26.967 1.00 78.98 ? 373 ASN A O 1 ATOM 2660 C CB . ASN A 1 349 ? 13.687 65.270 24.989 1.00 74.15 ? 373 ASN A CB 1 ATOM 2661 C CG . ASN A 1 349 ? 14.356 64.476 23.873 1.00 73.58 ? 373 ASN A CG 1 ATOM 2662 O OD1 . ASN A 1 349 ? 15.037 65.038 23.012 1.00 71.86 ? 373 ASN A OD1 1 ATOM 2663 N ND2 . ASN A 1 349 ? 14.160 63.160 23.884 1.00 71.01 ? 373 ASN A ND2 1 ATOM 2664 N N . GLY A 1 350 ? 14.730 67.344 27.913 1.00 73.18 ? 374 GLY A N 1 ATOM 2665 C CA . GLY A 1 350 ? 14.158 68.117 29.008 1.00 73.20 ? 374 GLY A CA 1 ATOM 2666 C C . GLY A 1 350 ? 13.735 67.304 30.216 1.00 74.73 ? 374 GLY A C 1 ATOM 2667 O O . GLY A 1 350 ? 13.852 67.755 31.357 1.00 71.50 ? 374 GLY A O 1 ATOM 2668 N N . GLU A 1 351 ? 13.219 66.107 29.959 1.00 77.48 ? 375 GLU A N 1 ATOM 2669 C CA . GLU A 1 351 ? 12.790 65.200 31.018 1.00 80.56 ? 375 GLU A CA 1 ATOM 2670 C C . GLU A 1 351 ? 14.039 64.686 31.735 1.00 84.42 ? 375 GLU A C 1 ATOM 2671 O O . GLU A 1 351 ? 15.005 64.271 31.093 1.00 76.95 ? 375 GLU A O 1 ATOM 2672 C CB . GLU A 1 351 ? 12.006 64.029 30.406 1.00 106.27 ? 375 GLU A CB 1 ATOM 2673 C CG . GLU A 1 351 ? 11.026 63.337 31.353 1.00 121.30 ? 375 GLU A CG 1 ATOM 2674 C CD . GLU A 1 351 ? 10.078 62.379 30.626 1.00 128.61 ? 375 GLU A CD 1 ATOM 2675 O OE1 . GLU A 1 351 ? 10.555 61.371 30.051 1.00 131.20 ? 375 GLU A OE1 1 ATOM 2676 O OE2 . GLU A 1 351 ? 8.852 62.637 30.628 1.00 131.26 ? 375 GLU A OE2 1 ATOM 2677 N N . PRO A 1 352 ? 14.050 64.748 33.078 1.00 93.95 ? 376 PRO A N 1 ATOM 2678 C CA . PRO A 1 352 ? 15.206 64.269 33.852 1.00 94.34 ? 376 PRO A CA 1 ATOM 2679 C C . PRO A 1 352 ? 15.395 62.776 33.609 1.00 91.44 ? 376 PRO A C 1 ATOM 2680 O O . PRO A 1 352 ? 14.417 62.028 33.571 1.00 92.45 ? 376 PRO A O 1 ATOM 2681 C CB . PRO A 1 352 ? 14.815 64.550 35.299 1.00 120.05 ? 376 PRO A CB 1 ATOM 2682 C CG . PRO A 1 352 ? 13.795 65.634 35.214 1.00 123.17 ? 376 PRO A CG 1 ATOM 2683 C CD . PRO A 1 352 ? 13.021 65.333 33.959 1.00 118.52 ? 376 PRO A CD 1 ATOM 2684 N N . LEU A 1 353 ? 16.652 62.354 33.467 1.00 85.36 ? 377 LEU A N 1 ATOM 2685 C CA . LEU A 1 353 ? 16.990 60.958 33.164 1.00 80.92 ? 377 LEU A CA 1 ATOM 2686 C C . LEU A 1 353 ? 16.205 59.945 33.990 1.00 81.71 ? 377 LEU A C 1 ATOM 2687 O O . LEU A 1 353 ? 15.628 59.002 33.439 1.00 76.74 ? 377 LEU A O 1 ATOM 2688 C CB . LEU A 1 353 ? 18.495 60.726 33.345 1.00 81.20 ? 377 LEU A CB 1 ATOM 2689 C CG . LEU A 1 353 ? 19.101 59.447 32.745 1.00 80.35 ? 377 LEU A CG 1 ATOM 2690 C CD1 . LEU A 1 353 ? 19.368 59.635 31.265 1.00 79.01 ? 377 LEU A CD1 1 ATOM 2691 C CD2 . LEU A 1 353 ? 20.393 59.095 33.476 1.00 80.68 ? 377 LEU A CD2 1 ATOM 2692 N N . GLN A 1 354 ? 16.184 60.162 35.306 1.00 85.91 ? 378 GLN A N 1 ATOM 2693 C CA . GLN A 1 354 ? 15.488 59.303 36.269 1.00 94.65 ? 378 GLN A CA 1 ATOM 2694 C C . GLN A 1 354 ? 14.076 58.886 35.825 1.00 92.96 ? 378 GLN A C 1 ATOM 2695 O O . GLN A 1 354 ? 13.699 57.723 35.956 1.00 87.92 ? 378 GLN A O 1 ATOM 2696 C CB . GLN A 1 354 ? 15.433 60.021 37.633 1.00 124.09 ? 378 GLN A CB 1 ATOM 2697 C CG . GLN A 1 354 ? 14.899 59.194 38.803 1.00 142.13 ? 378 GLN A CG 1 ATOM 2698 C CD . GLN A 1 354 ? 14.988 59.937 40.137 1.00 149.56 ? 378 GLN A CD 1 ATOM 2699 O OE1 . GLN A 1 354 ? 16.052 60.434 40.517 1.00 151.60 ? 378 GLN A OE1 1 ATOM 2700 N NE2 . GLN A 1 354 ? 13.870 60.009 40.854 1.00 151.21 ? 378 GLN A NE2 1 ATOM 2701 N N . SER A 1 355 ? 13.315 59.832 35.281 1.00 90.62 ? 379 SER A N 1 ATOM 2702 C CA . SER A 1 355 ? 11.939 59.575 34.847 1.00 91.32 ? 379 SER A CA 1 ATOM 2703 C C . SER A 1 355 ? 11.790 59.553 33.327 1.00 94.20 ? 379 SER A C 1 ATOM 2704 O O . SER A 1 355 ? 10.803 60.059 32.782 1.00 93.16 ? 379 SER A O 1 ATOM 2705 C CB . SER A 1 355 ? 11.013 60.650 35.432 1.00 110.43 ? 379 SER A CB 1 ATOM 2706 O OG . SER A 1 355 ? 11.279 61.921 34.860 1.00 110.97 ? 379 SER A OG 1 ATOM 2707 N N . ALA A 1 356 ? 12.763 58.952 32.650 1.00 102.39 ? 380 ALA A N 1 ATOM 2708 C CA . ALA A 1 356 ? 12.759 58.898 31.190 1.00 106.09 ? 380 ALA A CA 1 ATOM 2709 C C . ALA A 1 356 ? 12.370 57.524 30.652 1.00 109.01 ? 380 ALA A C 1 ATOM 2710 O O . ALA A 1 356 ? 12.483 56.526 31.368 1.00 111.84 ? 380 ALA A O 1 ATOM 2711 C CB . ALA A 1 356 ? 14.149 59.292 30.656 1.00 100.15 ? 380 ALA A CB 1 ATOM 2712 N N . PRO A 1 357 ? 11.883 57.457 29.387 1.00 131.66 ? 381 PRO A N 1 ATOM 2713 C CA . PRO A 1 357 ? 11.484 56.180 28.755 1.00 131.22 ? 381 PRO A CA 1 ATOM 2714 C C . PRO A 1 357 ? 12.699 55.245 28.827 1.00 125.09 ? 381 PRO A C 1 ATOM 2715 O O . PRO A 1 357 ? 13.703 55.483 28.143 1.00 142.93 ? 381 PRO A O 1 ATOM 2716 C CB . PRO A 1 357 ? 11.160 56.585 27.326 1.00 131.47 ? 381 PRO A CB 1 ATOM 2717 C CG . PRO A 1 357 ? 10.761 58.020 27.421 1.00 129.31 ? 381 PRO A CG 1 ATOM 2718 C CD . PRO A 1 357 ? 11.647 58.604 28.484 1.00 127.38 ? 381 PRO A CD 1 ATOM 2719 N N . PRO A 1 358 ? 12.590 54.140 29.599 1.00 105.53 ? 382 PRO A N 1 ATOM 2720 C CA . PRO A 1 358 ? 13.703 53.194 29.775 1.00 102.36 ? 382 PRO A CA 1 ATOM 2721 C C . PRO A 1 358 ? 14.408 52.725 28.529 1.00 106.96 ? 382 PRO A C 1 ATOM 2722 O O . PRO A 1 358 ? 13.763 52.513 27.510 1.00 107.40 ? 382 PRO A O 1 ATOM 2723 C CB . PRO A 1 358 ? 13.082 52.038 30.561 1.00 78.04 ? 382 PRO A CB 1 ATOM 2724 C CG . PRO A 1 358 ? 11.822 52.596 31.135 1.00 71.71 ? 382 PRO A CG 1 ATOM 2725 C CD . PRO A 1 358 ? 11.328 53.560 30.100 1.00 81.60 ? 382 PRO A CD 1 ATOM 2726 N N . ASN A 1 359 ? 15.732 52.571 28.612 1.00 116.98 ? 383 ASN A N 1 ATOM 2727 C CA . ASN A 1 359 ? 16.534 52.105 27.476 1.00 124.69 ? 383 ASN A CA 1 ATOM 2728 C C . ASN A 1 359 ? 17.663 51.186 27.947 1.00 126.18 ? 383 ASN A C 1 ATOM 2729 O O . ASN A 1 359 ? 18.544 51.597 28.714 1.00 128.96 ? 383 ASN A O 1 ATOM 2730 C CB . ASN A 1 359 ? 17.081 53.293 26.684 1.00 122.98 ? 383 ASN A CB 1 ATOM 2731 C CG . ASN A 1 359 ? 18.066 52.874 25.611 1.00 120.41 ? 383 ASN A CG 1 ATOM 2732 O OD1 . ASN A 1 359 ? 19.147 52.375 25.916 1.00 119.15 ? 383 ASN A OD1 1 ATOM 2733 N ND2 . ASN A 1 359 ? 17.701 53.079 24.347 1.00 119.22 ? 383 ASN A ND2 1 ATOM 2734 N N . PRO A 1 360 ? 17.655 49.927 27.465 1.00 136.34 ? 384 PRO A N 1 ATOM 2735 C CA . PRO A 1 360 ? 18.653 48.912 27.827 1.00 138.29 ? 384 PRO A CA 1 ATOM 2736 C C . PRO A 1 360 ? 20.045 49.141 27.259 1.00 142.25 ? 384 PRO A C 1 ATOM 2737 O O . PRO A 1 360 ? 21.040 48.699 27.837 1.00 157.49 ? 384 PRO A O 1 ATOM 2738 C CB . PRO A 1 360 ? 18.049 47.602 27.298 1.00 112.49 ? 384 PRO A CB 1 ATOM 2739 C CG . PRO A 1 360 ? 16.690 47.964 26.736 1.00 104.71 ? 384 PRO A CG 1 ATOM 2740 C CD . PRO A 1 360 ? 16.746 49.419 26.420 1.00 110.19 ? 384 PRO A CD 1 ATOM 2741 N N . ASN A 1 361 ? 20.100 49.831 26.123 1.00 123.87 ? 385 ASN A N 1 ATOM 2742 C CA . ASN A 1 361 ? 21.351 50.108 25.416 1.00 111.22 ? 385 ASN A CA 1 ATOM 2743 C C . ASN A 1 361 ? 22.183 51.222 26.059 1.00 102.09 ? 385 ASN A C 1 ATOM 2744 O O . ASN A 1 361 ? 23.228 51.611 25.527 1.00 90.60 ? 385 ASN A O 1 ATOM 2745 C CB . ASN A 1 361 ? 21.033 50.514 23.963 1.00 133.31 ? 385 ASN A CB 1 ATOM 2746 C CG . ASN A 1 361 ? 20.259 49.443 23.195 1.00 147.73 ? 385 ASN A CG 1 ATOM 2747 O OD1 . ASN A 1 361 ? 19.810 48.443 23.768 1.00 156.02 ? 385 ASN A OD1 1 ATOM 2748 N ND2 . ASN A 1 361 ? 20.093 49.658 21.887 1.00 155.14 ? 385 ASN A ND2 1 ATOM 2749 N N . ARG A 1 362 ? 21.731 51.716 27.209 1.00 100.66 ? 386 ARG A N 1 ATOM 2750 C CA . ARG A 1 362 ? 22.368 52.850 27.867 1.00 100.09 ? 386 ARG A CA 1 ATOM 2751 C C . ARG A 1 362 ? 22.886 52.535 29.256 1.00 99.35 ? 386 ARG A C 1 ATOM 2752 O O . ARG A 1 362 ? 22.143 52.058 30.111 1.00 101.26 ? 386 ARG A O 1 ATOM 2753 C CB . ARG A 1 362 ? 21.347 54.005 27.929 1.00 98.14 ? 386 ARG A CB 1 ATOM 2754 C CG . ARG A 1 362 ? 21.796 55.269 28.666 1.00 97.31 ? 386 ARG A CG 1 ATOM 2755 C CD . ARG A 1 362 ? 20.730 56.366 28.545 1.00 96.30 ? 386 ARG A CD 1 ATOM 2756 N NE . ARG A 1 362 ? 19.404 55.911 28.975 1.00 95.76 ? 386 ARG A NE 1 ATOM 2757 C CZ . ARG A 1 362 ? 18.247 56.415 28.543 1.00 95.18 ? 386 ARG A CZ 1 ATOM 2758 N NH1 . ARG A 1 362 ? 18.221 57.400 27.657 1.00 94.57 ? 386 ARG A NH1 1 ATOM 2759 N NH2 . ARG A 1 362 ? 17.105 55.924 28.999 1.00 95.54 ? 386 ARG A NH2 1 ATOM 2760 N N . GLU A 1 363 ? 24.178 52.776 29.463 1.00 98.51 ? 387 GLU A N 1 ATOM 2761 C CA . GLU A 1 363 ? 24.805 52.576 30.772 1.00 101.10 ? 387 GLU A CA 1 ATOM 2762 C C . GLU A 1 363 ? 25.366 53.912 31.265 1.00 92.14 ? 387 GLU A C 1 ATOM 2763 O O . GLU A 1 363 ? 26.156 54.564 30.579 1.00 81.03 ? 387 GLU A O 1 ATOM 2764 C CB . GLU A 1 363 ? 25.916 51.517 30.715 1.00 134.76 ? 387 GLU A CB 1 ATOM 2765 C CG . GLU A 1 363 ? 25.418 50.068 30.582 1.00 161.94 ? 387 GLU A CG 1 ATOM 2766 C CD . GLU A 1 363 ? 24.763 49.526 31.852 1.00 173.10 ? 387 GLU A CD 1 ATOM 2767 O OE1 . GLU A 1 363 ? 23.678 48.911 31.736 1.00 175.90 ? 387 GLU A OE1 1 ATOM 2768 O OE2 . GLU A 1 363 ? 25.332 49.705 32.954 1.00 175.53 ? 387 GLU A OE2 1 ATOM 2769 N N . VAL A 1 364 ? 24.938 54.310 32.460 1.00 83.31 ? 388 VAL A N 1 ATOM 2770 C CA . VAL A 1 364 ? 25.342 55.580 33.047 1.00 83.94 ? 388 VAL A CA 1 ATOM 2771 C C . VAL A 1 364 ? 26.429 55.392 34.102 1.00 85.84 ? 388 VAL A C 1 ATOM 2772 O O . VAL A 1 364 ? 26.339 54.509 34.956 1.00 87.32 ? 388 VAL A O 1 ATOM 2773 C CB . VAL A 1 364 ? 24.103 56.328 33.664 1.00 70.90 ? 388 VAL A CB 1 ATOM 2774 C CG1 . VAL A 1 364 ? 23.005 56.480 32.612 1.00 63.51 ? 388 VAL A CG1 1 ATOM 2775 C CG2 . VAL A 1 364 ? 23.552 55.572 34.868 1.00 65.23 ? 388 VAL A CG2 1 ATOM 2776 N N . ALA A 1 365 ? 27.477 56.206 34.018 1.00 89.54 ? 389 ALA A N 1 ATOM 2777 C CA . ALA A 1 365 ? 28.581 56.127 34.977 1.00 87.49 ? 389 ALA A CA 1 ATOM 2778 C C . ALA A 1 365 ? 28.963 57.520 35.454 1.00 85.46 ? 389 ALA A C 1 ATOM 2779 O O . ALA A 1 365 ? 30.051 58.011 35.170 1.00 87.07 ? 389 ALA A O 1 ATOM 2780 C CB . ALA A 1 365 ? 29.785 55.433 34.347 1.00 59.29 ? 389 ALA A CB 1 ATOM 2781 N N . GLY A 1 366 ? 28.051 58.139 36.193 1.00 78.72 ? 390 GLY A N 1 ATOM 2782 C CA . GLY A 1 366 ? 28.270 59.484 36.678 1.00 74.71 ? 390 GLY A CA 1 ATOM 2783 C C . GLY A 1 366 ? 28.299 60.461 35.520 1.00 73.96 ? 390 GLY A C 1 ATOM 2784 O O . GLY A 1 366 ? 27.285 60.678 34.854 1.00 73.47 ? 390 GLY A O 1 ATOM 2785 N N . ASP A 1 367 ? 29.476 61.023 35.266 1.00 70.96 ? 391 ASP A N 1 ATOM 2786 C CA . ASP A 1 367 ? 29.667 62.010 34.207 1.00 71.05 ? 391 ASP A CA 1 ATOM 2787 C C . ASP A 1 367 ? 29.817 61.415 32.811 1.00 70.57 ? 391 ASP A C 1 ATOM 2788 O O . ASP A 1 367 ? 30.034 62.143 31.841 1.00 67.67 ? 391 ASP A O 1 ATOM 2789 C CB . ASP A 1 367 ? 30.903 62.875 34.521 1.00 80.90 ? 391 ASP A CB 1 ATOM 2790 C CG . ASP A 1 367 ? 32.151 62.048 34.814 1.00 87.47 ? 391 ASP A CG 1 ATOM 2791 O OD1 . ASP A 1 367 ? 32.183 60.853 34.455 1.00 91.32 ? 391 ASP A OD1 1 ATOM 2792 O OD2 . ASP A 1 367 ? 33.109 62.603 35.396 1.00 90.61 ? 391 ASP A OD2 1 ATOM 2793 N N . THR A 1 368 ? 29.672 60.101 32.710 1.00 66.71 ? 392 THR A N 1 ATOM 2794 C CA . THR A 1 368 ? 29.872 59.412 31.450 1.00 64.87 ? 392 THR A CA 1 ATOM 2795 C C . THR A 1 368 ? 28.724 58.485 31.082 1.00 65.24 ? 392 THR A C 1 ATOM 2796 O O . THR A 1 368 ? 28.282 57.670 31.898 1.00 61.84 ? 392 THR A O 1 ATOM 2797 C CB . THR A 1 368 ? 31.192 58.578 31.509 1.00 71.38 ? 392 THR A CB 1 ATOM 2798 O OG1 . THR A 1 368 ? 32.271 59.416 31.955 1.00 73.88 ? 392 THR A OG1 1 ATOM 2799 C CG2 . THR A 1 368 ? 31.538 58.000 30.143 1.00 74.02 ? 392 THR A CG2 1 ATOM 2800 N N . ILE A 1 369 ? 28.227 58.641 29.855 1.00 77.02 ? 393 ILE A N 1 ATOM 2801 C CA . ILE A 1 369 ? 27.177 57.777 29.327 1.00 79.62 ? 393 ILE A CA 1 ATOM 2802 C C . ILE A 1 369 ? 27.772 56.997 28.153 1.00 80.11 ? 393 ILE A C 1 ATOM 2803 O O . ILE A 1 369 ? 28.609 57.513 27.403 1.00 81.87 ? 393 ILE A O 1 ATOM 2804 C CB . ILE A 1 369 ? 25.945 58.569 28.793 1.00 80.83 ? 393 ILE A CB 1 ATOM 2805 C CG1 . ILE A 1 369 ? 25.467 59.592 29.828 1.00 82.14 ? 393 ILE A CG1 1 ATOM 2806 C CG2 . ILE A 1 369 ? 24.818 57.612 28.414 1.00 79.75 ? 393 ILE A CG2 1 ATOM 2807 C CD1 . ILE A 1 369 ? 25.013 59.044 31.198 1.00 89.27 ? 393 ILE A CD1 1 ATOM 2808 N N . ILE A 1 370 ? 27.339 55.747 28.010 1.00 82.84 ? 394 ILE A N 1 ATOM 2809 C CA . ILE A 1 370 ? 27.786 54.902 26.912 1.00 84.05 ? 394 ILE A CA 1 ATOM 2810 C C . ILE A 1 370 ? 26.577 54.202 26.287 1.00 81.69 ? 394 ILE A C 1 ATOM 2811 O O . ILE A 1 370 ? 25.754 53.604 26.982 1.00 82.55 ? 394 ILE A O 1 ATOM 2812 C CB . ILE A 1 370 ? 28.900 53.890 27.390 1.00 96.42 ? 394 ILE A CB 1 ATOM 2813 C CG1 . ILE A 1 370 ? 29.499 53.151 26.190 1.00 98.80 ? 394 ILE A CG1 1 ATOM 2814 C CG2 . ILE A 1 370 ? 28.366 52.947 28.467 1.00 99.23 ? 394 ILE A CG2 1 ATOM 2815 C CD1 . ILE A 1 370 ? 30.799 52.404 26.486 1.00 98.07 ? 394 ILE A CD1 1 ATOM 2816 N N . PHE A 1 371 ? 26.460 54.332 24.968 1.00 80.40 ? 395 PHE A N 1 ATOM 2817 C CA . PHE A 1 371 ? 25.361 53.729 24.224 1.00 82.46 ? 395 PHE A CA 1 ATOM 2818 C C . PHE A 1 371 ? 25.836 52.518 23.413 1.00 81.73 ? 395 PHE A C 1 ATOM 2819 O O . PHE A 1 371 ? 26.469 52.669 22.363 1.00 82.38 ? 395 PHE A O 1 ATOM 2820 C CB . PHE A 1 371 ? 24.713 54.764 23.288 1.00 84.44 ? 395 PHE A CB 1 ATOM 2821 C CG . PHE A 1 371 ? 24.209 55.990 23.996 1.00 87.79 ? 395 PHE A CG 1 ATOM 2822 C CD1 . PHE A 1 371 ? 25.010 57.121 24.113 1.00 88.81 ? 395 PHE A CD1 1 ATOM 2823 C CD2 . PHE A 1 371 ? 22.933 56.015 24.547 1.00 88.65 ? 395 PHE A CD2 1 ATOM 2824 C CE1 . PHE A 1 371 ? 24.548 58.259 24.773 1.00 88.79 ? 395 PHE A CE1 1 ATOM 2825 C CE2 . PHE A 1 371 ? 22.464 57.148 25.209 1.00 88.24 ? 395 PHE A CE2 1 ATOM 2826 C CZ . PHE A 1 371 ? 23.273 58.272 25.318 1.00 88.35 ? 395 PHE A CZ 1 ATOM 2827 N N . ARG A 1 372 ? 25.531 51.321 23.917 1.00 85.85 ? 396 ARG A N 1 ATOM 2828 C CA . ARG A 1 372 ? 25.897 50.069 23.259 1.00 88.05 ? 396 ARG A CA 1 ATOM 2829 C C . ARG A 1 372 ? 24.813 49.637 22.279 1.00 85.93 ? 396 ARG A C 1 ATOM 2830 O O . ARG A 1 372 ? 23.626 49.760 22.577 1.00 80.69 ? 396 ARG A O 1 ATOM 2831 C CB . ARG A 1 372 ? 26.104 48.955 24.288 1.00 115.32 ? 396 ARG A CB 1 ATOM 2832 C CG . ARG A 1 372 ? 27.303 49.141 25.199 1.00 127.55 ? 396 ARG A CG 1 ATOM 2833 C CD . ARG A 1 372 ? 27.370 48.019 26.222 1.00 133.72 ? 396 ARG A CD 1 ATOM 2834 N NE . ARG A 1 372 ? 26.248 48.066 27.162 1.00 135.87 ? 396 ARG A NE 1 ATOM 2835 C CZ . ARG A 1 372 ? 25.778 47.015 27.832 1.00 136.38 ? 396 ARG A CZ 1 ATOM 2836 N NH1 . ARG A 1 372 ? 26.326 45.813 27.672 1.00 135.94 ? 396 ARG A NH1 1 ATOM 2837 N NH2 . ARG A 1 372 ? 24.753 47.167 28.662 1.00 136.60 ? 396 ARG A NH2 1 ATOM 2838 N N . ASP A 1 373 ? 25.233 49.115 21.123 1.00 88.95 ? 397 ASP A N 1 ATOM 2839 C CA . ASP A 1 373 ? 24.324 48.655 20.065 1.00 91.66 ? 397 ASP A CA 1 ATOM 2840 C C . ASP A 1 373 ? 23.265 49.720 19.750 1.00 89.70 ? 397 ASP A C 1 ATOM 2841 O O . ASP A 1 373 ? 22.059 49.495 19.885 1.00 82.57 ? 397 ASP A O 1 ATOM 2842 C CB . ASP A 1 373 ? 23.656 47.326 20.463 1.00 109.16 ? 397 ASP A CB 1 ATOM 2843 C CG . ASP A 1 373 ? 23.153 46.531 19.257 1.00 119.79 ? 397 ASP A CG 1 ATOM 2844 O OD1 . ASP A 1 373 ? 22.712 47.149 18.257 1.00 124.98 ? 397 ASP A OD1 1 ATOM 2845 O OD2 . ASP A 1 373 ? 23.185 45.280 19.322 1.00 124.98 ? 397 ASP A OD2 1 ATOM 2846 N N . THR A 1 374 ? 23.749 50.890 19.332 1.00 84.25 ? 398 THR A N 1 ATOM 2847 C CA . THR A 1 374 ? 22.892 52.029 18.992 1.00 84.04 ? 398 THR A CA 1 ATOM 2848 C C . THR A 1 374 ? 21.997 51.635 17.828 1.00 86.64 ? 398 THR A C 1 ATOM 2849 O O . THR A 1 374 ? 22.473 51.309 16.741 1.00 88.31 ? 398 THR A O 1 ATOM 2850 C CB . THR A 1 374 ? 23.750 53.266 18.641 1.00 87.14 ? 398 THR A CB 1 ATOM 2851 O OG1 . THR A 1 374 ? 24.684 53.505 19.702 1.00 87.00 ? 398 THR A OG1 1 ATOM 2852 C CG2 . THR A 1 374 ? 22.874 54.497 18.473 1.00 85.93 ? 398 THR A CG2 1 ATOM 2853 N N . GLN A 1 375 ? 20.693 51.687 18.054 1.00 92.11 ? 399 GLN A N 1 ATOM 2854 C CA . GLN A 1 375 ? 19.758 51.247 17.042 1.00 95.85 ? 399 GLN A CA 1 ATOM 2855 C C . GLN A 1 375 ? 18.815 52.318 16.562 1.00 97.12 ? 399 GLN A C 1 ATOM 2856 O O . GLN A 1 375 ? 18.806 53.430 17.060 1.00 88.89 ? 399 GLN A O 1 ATOM 2857 C CB . GLN A 1 375 ? 18.955 50.064 17.578 1.00 126.97 ? 399 GLN A CB 1 ATOM 2858 C CG . GLN A 1 375 ? 18.732 48.943 16.572 1.00 140.11 ? 399 GLN A CG 1 ATOM 2859 C CD . GLN A 1 375 ? 20.001 48.492 15.880 1.00 145.98 ? 399 GLN A CD 1 ATOM 2860 O OE1 . GLN A 1 375 ? 20.063 48.476 14.660 1.00 147.85 ? 399 GLN A OE1 1 ATOM 2861 N NE2 . GLN A 1 375 ? 21.011 48.114 16.653 1.00 146.96 ? 399 GLN A NE2 1 ATOM 2862 N N . ILE A 1 376 ? 18.020 51.952 15.573 1.00 102.01 ? 400 ILE A N 1 ATOM 2863 C CA . ILE A 1 376 ? 17.042 52.834 14.974 1.00 116.62 ? 400 ILE A CA 1 ATOM 2864 C C . ILE A 1 376 ? 16.347 53.746 15.933 1.00 117.40 ? 400 ILE A C 1 ATOM 2865 O O . ILE A 1 376 ? 16.137 54.908 15.653 1.00 118.16 ? 400 ILE A O 1 ATOM 2866 C CB . ILE A 1 376 ? 15.877 52.040 14.431 1.00 133.41 ? 400 ILE A CB 1 ATOM 2867 C CG1 . ILE A 1 376 ? 16.389 50.752 13.760 1.00 141.29 ? 400 ILE A CG1 1 ATOM 2868 C CG2 . ILE A 1 376 ? 15.050 52.910 13.499 1.00 140.65 ? 400 ILE A CG2 1 ATOM 2869 C CD1 . ILE A 1 376 ? 15.563 50.330 12.544 1.00 144.62 ? 400 ILE A CD1 1 ATOM 2870 N N . SER A 1 377 ? 15.945 53.186 17.058 1.00 137.66 ? 401 SER A N 1 ATOM 2871 C CA . SER A 1 377 ? 15.245 53.959 18.061 1.00 135.37 ? 401 SER A CA 1 ATOM 2872 C C . SER A 1 377 ? 16.319 54.832 18.611 1.00 127.24 ? 401 SER A C 1 ATOM 2873 O O . SER A 1 377 ? 17.290 55.124 17.949 1.00 135.80 ? 401 SER A O 1 ATOM 2874 C CB . SER A 1 377 ? 14.821 53.032 19.178 1.00 123.91 ? 401 SER A CB 1 ATOM 2875 O OG . SER A 1 377 ? 14.581 51.758 18.637 1.00 122.38 ? 401 SER A OG 1 ATOM 2876 N N . SER A 1 378 ? 16.123 55.250 19.846 1.00 90.44 ? 402 SER A N 1 ATOM 2877 C CA . SER A 1 378 ? 17.195 55.889 20.568 1.00 82.26 ? 402 SER A CA 1 ATOM 2878 C C . SER A 1 378 ? 17.704 57.200 20.052 1.00 78.40 ? 402 SER A C 1 ATOM 2879 O O . SER A 1 378 ? 18.720 57.675 20.520 1.00 61.44 ? 402 SER A O 1 ATOM 2880 C CB . SER A 1 378 ? 18.367 54.915 20.660 1.00 96.80 ? 402 SER A CB 1 ATOM 2881 O OG . SER A 1 378 ? 19.378 55.454 21.482 1.00 103.94 ? 402 SER A OG 1 ATOM 2882 N N . ARG A 1 379 ? 17.020 57.797 19.090 1.00 107.71 ? 403 ARG A N 1 ATOM 2883 C CA . ARG A 1 379 ? 17.441 59.113 18.632 1.00 119.89 ? 403 ARG A CA 1 ATOM 2884 C C . ARG A 1 379 ? 16.799 60.170 19.506 1.00 120.72 ? 403 ARG A C 1 ATOM 2885 O O . ARG A 1 379 ? 15.595 60.351 19.484 1.00 133.89 ? 403 ARG A O 1 ATOM 2886 C CB . ARG A 1 379 ? 17.038 59.344 17.188 1.00 124.52 ? 403 ARG A CB 1 ATOM 2887 C CG . ARG A 1 379 ? 16.983 58.079 16.402 1.00 119.58 ? 403 ARG A CG 1 ATOM 2888 C CD . ARG A 1 379 ? 16.210 58.273 15.144 1.00 117.09 ? 403 ARG A CD 1 ATOM 2889 N NE . ARG A 1 379 ? 17.069 58.763 14.084 1.00 117.29 ? 403 ARG A NE 1 ATOM 2890 C CZ . ARG A 1 379 ? 17.151 58.200 12.889 1.00 118.24 ? 403 ARG A CZ 1 ATOM 2891 N NH1 . ARG A 1 379 ? 16.424 57.132 12.606 1.00 117.94 ? 403 ARG A NH1 1 ATOM 2892 N NH2 . ARG A 1 379 ? 17.967 58.703 11.982 1.00 118.29 ? 403 ARG A NH2 1 ATOM 2893 N N . ALA A 1 380 ? 17.624 60.866 20.275 1.00 95.66 ? 404 ALA A N 1 ATOM 2894 C CA . ALA A 1 380 ? 17.159 61.908 21.184 1.00 80.53 ? 404 ALA A CA 1 ATOM 2895 C C . ALA A 1 380 ? 18.190 63.031 21.310 1.00 71.85 ? 404 ALA A C 1 ATOM 2896 O O . ALA A 1 380 ? 19.223 62.999 20.639 1.00 62.63 ? 404 ALA A O 1 ATOM 2897 C CB . ALA A 1 380 ? 16.855 61.300 22.549 1.00 100.60 ? 404 ALA A CB 1 ATOM 2898 N N . VAL A 1 381 ? 17.910 64.020 22.161 1.00 68.40 ? 405 VAL A N 1 ATOM 2899 C CA . VAL A 1 381 ? 18.805 65.170 22.333 1.00 67.75 ? 405 VAL A CA 1 ATOM 2900 C C . VAL A 1 381 ? 19.159 65.370 23.805 1.00 69.93 ? 405 VAL A C 1 ATOM 2901 O O . VAL A 1 381 ? 18.559 66.193 24.497 1.00 74.00 ? 405 VAL A O 1 ATOM 2902 C CB . VAL A 1 381 ? 18.156 66.470 21.777 1.00 58.22 ? 405 VAL A CB 1 ATOM 2903 C CG1 . VAL A 1 381 ? 19.231 67.515 21.524 1.00 55.39 ? 405 VAL A CG1 1 ATOM 2904 C CG2 . VAL A 1 381 ? 17.389 66.187 20.492 1.00 54.80 ? 405 VAL A CG2 1 ATOM 2905 N N . TYR A 1 382 ? 20.155 64.617 24.263 1.00 66.90 ? 406 TYR A N 1 ATOM 2906 C CA . TYR A 1 382 ? 20.584 64.633 25.658 1.00 64.31 ? 406 TYR A CA 1 ATOM 2907 C C . TYR A 1 382 ? 21.122 65.970 26.152 1.00 62.96 ? 406 TYR A C 1 ATOM 2908 O O . TYR A 1 382 ? 21.645 66.773 25.367 1.00 64.10 ? 406 TYR A O 1 ATOM 2909 C CB . TYR A 1 382 ? 21.611 63.521 25.893 1.00 59.71 ? 406 TYR A CB 1 ATOM 2910 C CG . TYR A 1 382 ? 21.027 62.137 25.767 1.00 55.96 ? 406 TYR A CG 1 ATOM 2911 C CD1 . TYR A 1 382 ? 20.737 61.592 24.518 1.00 55.07 ? 406 TYR A CD1 1 ATOM 2912 C CD2 . TYR A 1 382 ? 20.747 61.377 26.900 1.00 55.05 ? 406 TYR A CD2 1 ATOM 2913 C CE1 . TYR A 1 382 ? 20.183 60.325 24.397 1.00 54.96 ? 406 TYR A CE1 1 ATOM 2914 C CE2 . TYR A 1 382 ? 20.194 60.112 26.796 1.00 54.34 ? 406 TYR A CE2 1 ATOM 2915 C CZ . TYR A 1 382 ? 19.914 59.590 25.540 1.00 56.09 ? 406 TYR A CZ 1 ATOM 2916 O OH . TYR A 1 382 ? 19.366 58.329 25.425 1.00 57.60 ? 406 TYR A OH 1 ATOM 2917 N N . GLN A 1 383 ? 20.973 66.203 27.457 1.00 57.86 ? 407 GLN A N 1 ATOM 2918 C CA . GLN A 1 383 ? 21.426 67.438 28.098 1.00 55.00 ? 407 GLN A CA 1 ATOM 2919 C C . GLN A 1 383 ? 22.431 67.181 29.201 1.00 54.20 ? 407 GLN A C 1 ATOM 2920 O O . GLN A 1 383 ? 22.429 66.125 29.820 1.00 51.95 ? 407 GLN A O 1 ATOM 2921 C CB . GLN A 1 383 ? 20.247 68.184 28.744 1.00 57.32 ? 407 GLN A CB 1 ATOM 2922 C CG . GLN A 1 383 ? 19.485 69.111 27.834 1.00 59.47 ? 407 GLN A CG 1 ATOM 2923 C CD . GLN A 1 383 ? 18.530 68.383 26.920 1.00 61.31 ? 407 GLN A CD 1 ATOM 2924 O OE1 . GLN A 1 383 ? 18.264 68.840 25.804 1.00 61.76 ? 407 GLN A OE1 1 ATOM 2925 N NE2 . GLN A 1 383 ? 17.997 67.249 27.385 1.00 59.89 ? 407 GLN A NE2 1 ATOM 2926 N N . CYS A 1 384 ? 23.297 68.155 29.431 1.00 57.99 ? 408 CYS A N 1 ATOM 2927 C CA . CYS A 1 384 ? 24.206 68.066 30.539 1.00 60.36 ? 408 CYS A CA 1 ATOM 2928 C C . CYS A 1 384 ? 24.253 69.365 31.332 1.00 58.14 ? 408 CYS A C 1 ATOM 2929 O O . CYS A 1 384 ? 24.554 70.432 30.786 1.00 54.55 ? 408 CYS A O 1 ATOM 2930 C CB . CYS A 1 384 ? 25.630 67.714 30.106 1.00 71.25 ? 408 CYS A CB 1 ATOM 2931 S SG . CYS A 1 384 ? 26.564 67.189 31.560 1.00 83.69 ? 408 CYS A SG 1 ATOM 2932 N N . ASN A 1 385 ? 23.920 69.268 32.617 1.00 58.03 ? 409 ASN A N 1 ATOM 2933 C CA . ASN A 1 385 ? 24.078 70.396 33.512 1.00 57.95 ? 409 ASN A CA 1 ATOM 2934 C C . ASN A 1 385 ? 25.223 70.068 34.488 1.00 57.29 ? 409 ASN A C 1 ATOM 2935 O O . ASN A 1 385 ? 25.110 69.153 35.300 1.00 60.56 ? 409 ASN A O 1 ATOM 2936 C CB . ASN A 1 385 ? 22.780 70.688 34.295 1.00 52.58 ? 409 ASN A CB 1 ATOM 2937 C CG . ASN A 1 385 ? 22.863 71.972 35.135 1.00 54.22 ? 409 ASN A CG 1 ATOM 2938 O OD1 . ASN A 1 385 ? 23.863 72.700 35.073 1.00 53.31 ? 409 ASN A OD1 1 ATOM 2939 N ND2 . ASN A 1 385 ? 21.817 72.253 35.923 1.00 55.81 ? 409 ASN A ND2 1 ATOM 2940 N N . THR A 1 386 ? 26.351 70.759 34.348 1.00 56.19 ? 410 THR A N 1 ATOM 2941 C CA . THR A 1 386 ? 27.434 70.623 35.331 1.00 55.19 ? 410 THR A CA 1 ATOM 2942 C C . THR A 1 386 ? 27.459 71.935 36.092 1.00 52.66 ? 410 THR A C 1 ATOM 2943 O O . THR A 1 386 ? 27.674 73.007 35.522 1.00 51.85 ? 410 THR A O 1 ATOM 2944 C CB . THR A 1 386 ? 28.824 70.337 34.753 1.00 48.51 ? 410 THR A CB 1 ATOM 2945 O OG1 . THR A 1 386 ? 29.005 71.033 33.513 1.00 51.64 ? 410 THR A OG1 1 ATOM 2946 C CG2 . THR A 1 386 ? 28.989 68.865 34.556 1.00 51.68 ? 410 THR A CG2 1 ATOM 2947 N N . SER A 1 387 ? 27.290 71.823 37.401 1.00 52.89 ? 411 SER A N 1 ATOM 2948 C CA . SER A 1 387 ? 27.116 72.993 38.234 1.00 54.20 ? 411 SER A CA 1 ATOM 2949 C C . SER A 1 387 ? 27.758 72.905 39.587 1.00 56.07 ? 411 SER A C 1 ATOM 2950 O O . SER A 1 387 ? 28.072 71.824 40.090 1.00 58.96 ? 411 SER A O 1 ATOM 2951 C CB . SER A 1 387 ? 25.599 73.177 38.462 1.00 45.57 ? 411 SER A CB 1 ATOM 2952 O OG . SER A 1 387 ? 25.001 71.964 38.942 1.00 41.67 ? 411 SER A OG 1 ATOM 2953 N N . ASN A 1 388 ? 27.974 74.080 40.149 1.00 53.84 ? 412 ASN A N 1 ATOM 2954 C CA . ASN A 1 388 ? 28.403 74.200 41.516 1.00 54.24 ? 412 ASN A CA 1 ATOM 2955 C C . ASN A 1 388 ? 27.857 75.523 42.043 1.00 56.24 ? 412 ASN A C 1 ATOM 2956 O O . ASN A 1 388 ? 27.222 76.291 41.310 1.00 53.92 ? 412 ASN A O 1 ATOM 2957 C CB . ASN A 1 388 ? 29.914 74.118 41.676 1.00 55.80 ? 412 ASN A CB 1 ATOM 2958 C CG . ASN A 1 388 ? 30.654 75.240 40.982 1.00 54.78 ? 412 ASN A CG 1 ATOM 2959 O OD1 . ASN A 1 388 ? 31.870 75.175 40.833 1.00 57.30 ? 412 ASN A OD1 1 ATOM 2960 N ND2 . ASN A 1 388 ? 29.943 76.268 40.560 1.00 55.94 ? 412 ASN A ND2 1 ATOM 2961 N N . GLU A 1 389 ? 28.109 75.770 43.321 1.00 64.27 ? 413 GLU A N 1 ATOM 2962 C CA . GLU A 1 389 ? 27.679 76.969 44.014 1.00 69.03 ? 413 GLU A CA 1 ATOM 2963 C C . GLU A 1 389 ? 27.751 78.229 43.163 1.00 66.23 ? 413 GLU A C 1 ATOM 2964 O O . GLU A 1 389 ? 26.877 79.080 43.240 1.00 66.41 ? 413 GLU A O 1 ATOM 2965 C CB . GLU A 1 389 ? 28.594 77.156 45.231 1.00 81.74 ? 413 GLU A CB 1 ATOM 2966 C CG . GLU A 1 389 ? 28.008 77.936 46.384 1.00 95.25 ? 413 GLU A CG 1 ATOM 2967 C CD . GLU A 1 389 ? 28.957 77.994 47.575 1.00 100.51 ? 413 GLU A CD 1 ATOM 2968 O OE1 . GLU A 1 389 ? 28.639 78.715 48.554 1.00 102.33 ? 413 GLU A OE1 1 ATOM 2969 O OE2 . GLU A 1 389 ? 30.014 77.315 47.522 1.00 101.83 ? 413 GLU A OE2 1 ATOM 2970 N N . HIS A 1 390 ? 28.778 78.307 42.321 1.00 57.19 ? 414 HIS A N 1 ATOM 2971 C CA . HIS A 1 390 ? 29.103 79.524 41.574 1.00 50.84 ? 414 HIS A CA 1 ATOM 2972 C C . HIS A 1 390 ? 28.664 79.647 40.126 1.00 47.92 ? 414 HIS A C 1 ATOM 2973 O O . HIS A 1 390 ? 28.888 80.683 39.502 1.00 46.04 ? 414 HIS A O 1 ATOM 2974 C CB . HIS A 1 390 ? 30.627 79.733 41.653 1.00 50.77 ? 414 HIS A CB 1 ATOM 2975 C CG . HIS A 1 390 ? 31.159 79.824 43.051 1.00 53.55 ? 414 HIS A CG 1 ATOM 2976 N ND1 . HIS A 1 390 ? 31.960 78.849 43.611 1.00 54.03 ? 414 HIS A ND1 1 ATOM 2977 C CD2 . HIS A 1 390 ? 31.005 80.778 44.000 1.00 53.81 ? 414 HIS A CD2 1 ATOM 2978 C CE1 . HIS A 1 390 ? 32.277 79.200 44.845 1.00 53.32 ? 414 HIS A CE1 1 ATOM 2979 N NE2 . HIS A 1 390 ? 31.710 80.365 45.104 1.00 54.54 ? 414 HIS A NE2 1 ATOM 2980 N N . GLY A 1 391 ? 28.053 78.599 39.588 1.00 43.41 ? 415 GLY A N 1 ATOM 2981 C CA . GLY A 1 391 ? 27.621 78.628 38.199 1.00 41.14 ? 415 GLY A CA 1 ATOM 2982 C C . GLY A 1 391 ? 27.366 77.250 37.608 1.00 43.95 ? 415 GLY A C 1 ATOM 2983 O O . GLY A 1 391 ? 27.546 76.232 38.278 1.00 44.18 ? 415 GLY A O 1 ATOM 2984 N N . TYR A 1 392 ? 26.928 77.212 36.357 1.00 47.79 ? 416 TYR A N 1 ATOM 2985 C CA . TYR A 1 392 ? 26.673 75.943 35.690 1.00 49.32 ? 416 TYR A CA 1 ATOM 2986 C C . TYR A 1 392 ? 27.017 76.022 34.202 1.00 50.32 ? 416 TYR A C 1 ATOM 2987 O O . TYR A 1 392 ? 27.334 77.100 33.696 1.00 51.16 ? 416 TYR A O 1 ATOM 2988 C CB . TYR A 1 392 ? 25.190 75.548 35.847 1.00 54.36 ? 416 TYR A CB 1 ATOM 2989 C CG . TYR A 1 392 ? 24.208 76.421 35.082 1.00 59.25 ? 416 TYR A CG 1 ATOM 2990 C CD1 . TYR A 1 392 ? 23.774 76.061 33.798 1.00 60.25 ? 416 TYR A CD1 1 ATOM 2991 C CD2 . TYR A 1 392 ? 23.719 77.606 35.634 1.00 58.53 ? 416 TYR A CD2 1 ATOM 2992 C CE1 . TYR A 1 392 ? 22.885 76.853 33.094 1.00 61.34 ? 416 TYR A CE1 1 ATOM 2993 C CE2 . TYR A 1 392 ? 22.829 78.407 34.933 1.00 60.01 ? 416 TYR A CE2 1 ATOM 2994 C CZ . TYR A 1 392 ? 22.415 78.023 33.664 1.00 61.41 ? 416 TYR A CZ 1 ATOM 2995 O OH . TYR A 1 392 ? 21.523 78.799 32.964 1.00 61.06 ? 416 TYR A OH 1 ATOM 2996 N N . LEU A 1 393 ? 26.998 74.869 33.530 1.00 49.65 ? 417 LEU A N 1 ATOM 2997 C CA . LEU A 1 393 ? 27.176 74.796 32.082 1.00 48.62 ? 417 LEU A CA 1 ATOM 2998 C C . LEU A 1 393 ? 26.145 73.822 31.531 1.00 49.26 ? 417 LEU A C 1 ATOM 2999 O O . LEU A 1 393 ? 25.970 72.721 32.078 1.00 51.70 ? 417 LEU A O 1 ATOM 3000 C CB . LEU A 1 393 ? 28.561 74.318 31.674 1.00 43.42 ? 417 LEU A CB 1 ATOM 3001 C CG . LEU A 1 393 ? 29.743 75.271 31.851 1.00 44.54 ? 417 LEU A CG 1 ATOM 3002 C CD1 . LEU A 1 393 ? 31.031 74.488 31.682 1.00 41.78 ? 417 LEU A CD1 1 ATOM 3003 C CD2 . LEU A 1 393 ? 29.666 76.456 30.879 1.00 43.54 ? 417 LEU A CD2 1 ATOM 3004 N N . LEU A 1 394 ? 25.477 74.224 30.447 1.00 46.65 ? 418 LEU A N 1 ATOM 3005 C CA . LEU A 1 394 ? 24.444 73.397 29.826 1.00 48.38 ? 418 LEU A CA 1 ATOM 3006 C C . LEU A 1 394 ? 24.818 73.027 28.405 1.00 49.03 ? 418 LEU A C 1 ATOM 3007 O O . LEU A 1 394 ? 24.922 73.885 27.523 1.00 48.00 ? 418 LEU A O 1 ATOM 3008 C CB . LEU A 1 394 ? 23.099 74.142 29.844 1.00 52.56 ? 418 LEU A CB 1 ATOM 3009 C CG . LEU A 1 394 ? 21.725 73.468 29.607 1.00 53.04 ? 418 LEU A CG 1 ATOM 3010 C CD1 . LEU A 1 394 ? 21.383 73.414 28.137 1.00 54.90 ? 418 LEU A CD1 1 ATOM 3011 C CD2 . LEU A 1 394 ? 21.658 72.092 30.238 1.00 54.16 ? 418 LEU A CD2 1 ATOM 3012 N N . ALA A 1 395 ? 25.026 71.738 28.186 1.00 52.60 ? 419 ALA A N 1 ATOM 3013 C CA . ALA A 1 395 ? 25.377 71.269 26.859 1.00 57.21 ? 419 ALA A CA 1 ATOM 3014 C C . ALA A 1 395 ? 24.289 70.412 26.242 1.00 58.32 ? 419 ALA A C 1 ATOM 3015 O O . ALA A 1 395 ? 23.693 69.567 26.914 1.00 57.73 ? 419 ALA A O 1 ATOM 3016 C CB . ALA A 1 395 ? 26.689 70.469 26.905 1.00 57.04 ? 419 ALA A CB 1 ATOM 3017 N N . ASN A 1 396 ? 24.019 70.670 24.963 1.00 67.23 ? 420 ASN A N 1 ATOM 3018 C CA . ASN A 1 396 ? 23.079 69.857 24.199 1.00 67.12 ? 420 ASN A CA 1 ATOM 3019 C C . ASN A 1 396 ? 23.891 68.985 23.256 1.00 66.50 ? 420 ASN A C 1 ATOM 3020 O O . ASN A 1 396 ? 24.846 69.456 22.632 1.00 67.88 ? 420 ASN A O 1 ATOM 3021 C CB . ASN A 1 396 ? 22.135 70.722 23.376 1.00 62.09 ? 420 ASN A CB 1 ATOM 3022 C CG . ASN A 1 396 ? 21.036 71.324 24.207 1.00 61.65 ? 420 ASN A CG 1 ATOM 3023 O OD1 . ASN A 1 396 ? 20.022 70.677 24.481 1.00 59.97 ? 420 ASN A OD1 1 ATOM 3024 N ND2 . ASN A 1 396 ? 21.230 72.575 24.625 1.00 60.39 ? 420 ASN A ND2 1 ATOM 3025 N N . ALA A 1 397 ? 23.518 67.712 23.176 1.00 60.55 ? 421 ALA A N 1 ATOM 3026 C CA . ALA A 1 397 ? 24.168 66.777 22.264 1.00 59.57 ? 421 ALA A CA 1 ATOM 3027 C C . ALA A 1 397 ? 23.193 65.674 21.855 1.00 61.81 ? 421 ALA A C 1 ATOM 3028 O O . ALA A 1 397 ? 22.665 64.963 22.719 1.00 63.22 ? 421 ALA A O 1 ATOM 3029 C CB . ALA A 1 397 ? 25.402 66.179 22.904 1.00 46.83 ? 421 ALA A CB 1 ATOM 3030 N N . PHE A 1 398 ? 22.950 65.535 20.546 1.00 64.48 ? 422 PHE A N 1 ATOM 3031 C CA . PHE A 1 398 ? 22.028 64.504 20.048 1.00 69.63 ? 422 PHE A CA 1 ATOM 3032 C C . PHE A 1 398 ? 22.713 63.189 19.709 1.00 70.48 ? 422 PHE A C 1 ATOM 3033 O O . PHE A 1 398 ? 23.931 63.136 19.615 1.00 67.66 ? 422 PHE A O 1 ATOM 3034 C CB . PHE A 1 398 ? 21.184 65.016 18.859 1.00 80.92 ? 422 PHE A CB 1 ATOM 3035 C CG . PHE A 1 398 ? 21.983 65.444 17.654 1.00 89.16 ? 422 PHE A CG 1 ATOM 3036 C CD1 . PHE A 1 398 ? 22.533 64.502 16.785 1.00 92.24 ? 422 PHE A CD1 1 ATOM 3037 C CD2 . PHE A 1 398 ? 22.156 66.801 17.370 1.00 92.73 ? 422 PHE A CD2 1 ATOM 3038 C CE1 . PHE A 1 398 ? 23.259 64.906 15.652 1.00 93.22 ? 422 PHE A CE1 1 ATOM 3039 C CE2 . PHE A 1 398 ? 22.878 67.215 16.244 1.00 93.99 ? 422 PHE A CE2 1 ATOM 3040 C CZ . PHE A 1 398 ? 23.427 66.262 15.379 1.00 93.95 ? 422 PHE A CZ 1 ATOM 3041 N N . VAL A 1 399 ? 21.917 62.131 19.552 1.00 78.16 ? 423 VAL A N 1 ATOM 3042 C CA . VAL A 1 399 ? 22.428 60.780 19.284 1.00 80.04 ? 423 VAL A CA 1 ATOM 3043 C C . VAL A 1 399 ? 21.692 60.159 18.095 1.00 84.84 ? 423 VAL A C 1 ATOM 3044 O O . VAL A 1 399 ? 20.867 59.254 18.242 1.00 89.65 ? 423 VAL A O 1 ATOM 3045 C CB . VAL A 1 399 ? 22.278 59.858 20.559 1.00 68.19 ? 423 VAL A CB 1 ATOM 3046 C CG1 . VAL A 1 399 ? 22.896 58.489 20.311 1.00 60.51 ? 423 VAL A CG1 1 ATOM 3047 C CG2 . VAL A 1 399 ? 22.949 60.506 21.757 1.00 60.66 ? 423 VAL A CG2 1 ATOM 3048 N N . SER A 1 400 ? 22.010 60.661 16.909 1.00 85.72 ? 424 SER A N 1 ATOM 3049 C CA . SER A 1 400 ? 21.384 60.188 15.680 1.00 86.27 ? 424 SER A CA 1 ATOM 3050 C C . SER A 1 400 ? 22.037 58.936 15.096 1.00 86.47 ? 424 SER A C 1 ATOM 3051 O O . SER A 1 400 ? 23.263 58.807 15.100 1.00 85.75 ? 424 SER A O 1 ATOM 3052 C CB . SER A 1 400 ? 21.407 61.303 14.625 1.00 84.18 ? 424 SER A CB 1 ATOM 3053 O OG . SER A 1 400 ? 22.726 61.792 14.446 1.00 86.94 ? 424 SER A OG 1 ATOM 3054 N N . VAL A 1 401 ? 21.198 58.009 14.624 1.00 86.71 ? 425 VAL A N 1 ATOM 3055 C CA . VAL A 1 401 ? 21.658 56.792 13.949 1.00 87.53 ? 425 VAL A CA 1 ATOM 3056 C C . VAL A 1 401 ? 21.653 57.027 12.429 1.00 86.33 ? 425 VAL A C 1 ATOM 3057 O O . VAL A 1 401 ? 20.794 57.742 11.900 1.00 83.76 ? 425 VAL A O 1 ATOM 3058 C CB . VAL A 1 401 ? 20.773 55.562 14.331 1.00 101.48 ? 425 VAL A CB 1 ATOM 3059 C CG1 . VAL A 1 401 ? 20.070 54.958 13.113 1.00 106.63 ? 425 VAL A CG1 1 ATOM 3060 C CG2 . VAL A 1 401 ? 21.636 54.520 15.040 1.00 106.62 ? 425 VAL A CG2 1 ATOM 3061 N N . LEU A 1 402 ? 22.627 56.436 11.740 1.00 96.82 ? 426 LEU A N 1 ATOM 3062 C CA . LEU A 1 402 ? 22.769 56.593 10.289 1.00 99.45 ? 426 LEU A CA 1 ATOM 3063 C C . LEU A 1 402 ? 22.078 55.449 9.538 1.00 101.66 ? 426 LEU A C 1 ATOM 3064 O O . LEU A 1 402 ? 21.154 54.859 10.132 1.00 104.66 ? 426 LEU A O 1 ATOM 3065 C CB . LEU A 1 402 ? 24.258 56.666 9.913 1.00 87.48 ? 426 LEU A CB 1 ATOM 3066 C CG . LEU A 1 402 ? 24.676 57.790 8.945 1.00 86.14 ? 426 LEU A CG 1 ATOM 3067 C CD1 . LEU A 1 402 ? 26.172 58.049 9.076 1.00 83.94 ? 426 LEU A CD1 1 ATOM 3068 C CD2 . LEU A 1 402 ? 24.284 57.478 7.487 1.00 85.78 ? 426 LEU A CD2 1 HETATM 3069 C C1 . NAG B 2 . ? 21.718 73.403 36.508 1.00 62.03 ? 1 NAG A C1 1 HETATM 3070 C C2 . NAG B 2 . ? 20.593 74.400 36.193 1.00 64.13 ? 1 NAG A C2 1 HETATM 3071 C C3 . NAG B 2 . ? 20.681 75.574 37.169 1.00 67.57 ? 1 NAG A C3 1 HETATM 3072 C C4 . NAG B 2 . ? 20.577 75.039 38.592 1.00 68.91 ? 1 NAG A C4 1 HETATM 3073 C C5 . NAG B 2 . ? 21.710 74.035 38.827 1.00 67.89 ? 1 NAG A C5 1 HETATM 3074 C C6 . NAG B 2 . ? 21.631 73.401 40.197 1.00 68.89 ? 1 NAG A C6 1 HETATM 3075 C C7 . NAG B 2 . ? 19.869 74.393 33.903 1.00 63.01 ? 1 NAG A C7 1 HETATM 3076 C C8 . NAG B 2 . ? 19.703 75.220 32.641 1.00 60.87 ? 1 NAG A C8 1 HETATM 3077 N N2 . NAG B 2 . ? 20.697 74.871 34.826 1.00 63.93 ? 1 NAG A N2 1 HETATM 3078 O O3 . NAG B 2 . ? 19.632 76.504 36.927 1.00 68.13 ? 1 NAG A O3 1 HETATM 3079 O O4 . NAG B 2 . ? 20.648 76.106 39.525 1.00 69.30 ? 1 NAG A O4 1 HETATM 3080 O O5 . NAG B 2 . ? 21.613 72.955 37.866 1.00 65.21 ? 1 NAG A O5 1 HETATM 3081 O O6 . NAG B 2 . ? 20.708 72.318 40.195 1.00 67.67 ? 1 NAG A O6 1 HETATM 3082 O O7 . NAG B 2 . ? 19.242 73.334 34.036 1.00 62.95 ? 1 NAG A O7 1 HETATM 3083 O O . HOH C 3 . ? 34.126 80.209 50.293 1.00 39.32 ? 2 HOH A O 1 HETATM 3084 O O . HOH C 3 . ? 49.364 106.774 68.604 1.00 60.66 ? 3 HOH A O 1 HETATM 3085 O O . HOH C 3 . ? 27.976 101.455 29.000 1.00 71.21 ? 4 HOH A O 1 HETATM 3086 O O . HOH C 3 . ? 37.052 90.614 55.552 1.00 43.87 ? 5 HOH A O 1 HETATM 3087 O O . HOH C 3 . ? 36.108 63.589 19.740 1.00 60.23 ? 6 HOH A O 1 HETATM 3088 O O . HOH C 3 . ? 35.805 99.248 49.154 1.00 54.53 ? 7 HOH A O 1 HETATM 3089 O O . HOH C 3 . ? -8.178 78.781 28.816 1.00 83.72 ? 8 HOH A O 1 HETATM 3090 O O . HOH C 3 . ? 32.610 64.533 24.646 1.00 59.23 ? 9 HOH A O 1 HETATM 3091 O O . HOH C 3 . ? 53.196 104.391 48.667 1.00 57.64 ? 10 HOH A O 1 HETATM 3092 O O . HOH C 3 . ? 29.492 92.924 54.975 1.00 85.64 ? 11 HOH A O 1 HETATM 3093 O O . HOH C 3 . ? 21.214 70.472 19.911 1.00 62.92 ? 12 HOH A O 1 HETATM 3094 O O . HOH C 3 . ? 41.079 82.829 32.302 1.00 54.97 ? 13 HOH A O 1 HETATM 3095 O O . HOH C 3 . ? 39.556 118.244 48.748 1.00 64.25 ? 14 HOH A O 1 HETATM 3096 O O . HOH C 3 . ? 30.018 76.349 26.933 1.00 78.74 ? 15 HOH A O 1 HETATM 3097 O O . HOH C 3 . ? 38.396 91.816 44.809 1.00 54.07 ? 16 HOH A O 1 HETATM 3098 O O . HOH C 3 . ? 35.372 79.644 36.150 1.00 59.81 ? 17 HOH A O 1 HETATM 3099 O O . HOH C 3 . ? 29.742 103.186 32.788 1.00 94.86 ? 18 HOH A O 1 HETATM 3100 O O . HOH C 3 . ? 5.763 72.270 20.992 1.00 68.27 ? 19 HOH A O 1 HETATM 3101 O O . HOH C 3 . ? 25.381 72.187 23.424 1.00 71.26 ? 20 HOH A O 1 HETATM 3102 O O . HOH C 3 . ? 41.676 78.690 46.885 1.00 72.96 ? 21 HOH A O 1 HETATM 3103 O O . HOH C 3 . ? 23.632 106.513 52.859 1.00 98.35 ? 22 HOH A O 1 HETATM 3104 O O . HOH C 3 . ? 21.326 81.018 34.210 1.00 68.31 ? 23 HOH A O 1 HETATM 3105 O O . HOH C 3 . ? 3.106 73.778 34.044 1.00 62.33 ? 24 HOH A O 1 HETATM 3106 O O . HOH C 3 . ? 0.344 88.026 38.723 1.00 73.53 ? 429 HOH A O 1 HETATM 3107 O O . HOH C 3 . ? 27.307 70.521 22.250 1.00 77.79 ? 430 HOH A O 1 HETATM 3108 O O . HOH C 3 . ? 20.142 88.333 33.685 1.00 110.43 ? 431 HOH A O 1 HETATM 3109 O O . HOH C 3 . ? 57.410 84.644 43.547 1.00 121.97 ? 432 HOH A O 1 HETATM 3110 O O . HOH C 3 . ? 34.262 97.707 46.329 1.00 109.53 ? 433 HOH A O 1 HETATM 3111 O O . HOH C 3 . ? 34.629 94.428 47.148 1.00 136.62 ? 434 HOH A O 1 HETATM 3112 O O . HOH C 3 . ? 8.412 87.267 33.964 1.00 93.17 ? 435 HOH A O 1 HETATM 3113 O O . HOH C 3 . ? 36.378 69.058 37.963 1.00 125.69 ? 436 HOH A O 1 HETATM 3114 O O . HOH C 3 . ? 61.873 91.949 45.285 1.00 73.83 ? 437 HOH A O 1 HETATM 3115 O O . HOH C 3 . ? 38.636 79.874 26.603 1.00 110.08 ? 438 HOH A O 1 HETATM 3116 O O . HOH C 3 . ? 37.446 68.173 45.403 1.00 86.71 ? 439 HOH A O 1 HETATM 3117 O O . HOH C 3 . ? 47.604 107.610 48.267 1.00 169.72 ? 440 HOH A O 1 HETATM 3118 O O . HOH C 3 . ? 17.000 97.692 41.828 1.00 99.62 ? 441 HOH A O 1 HETATM 3119 O O . HOH C 3 . ? 55.713 99.467 47.960 1.00 121.30 ? 442 HOH A O 1 HETATM 3120 O O . HOH C 3 . ? 25.714 74.229 8.129 1.00 85.47 ? 443 HOH A O 1 HETATM 3121 O O . HOH C 3 . ? 15.535 70.111 37.275 1.00 101.67 ? 444 HOH A O 1 HETATM 3122 O O . HOH C 3 . ? 40.747 73.076 30.711 1.00 88.83 ? 445 HOH A O 1 HETATM 3123 O O . HOH C 3 . ? 6.857 66.806 10.568 1.00 90.31 ? 446 HOH A O 1 HETATM 3124 O O . HOH C 3 . ? 19.124 59.918 6.339 1.00 95.34 ? 447 HOH A O 1 HETATM 3125 O O . HOH C 3 . ? 3.673 97.520 16.079 1.00 87.50 ? 448 HOH A O 1 HETATM 3126 O O . HOH C 3 . ? 14.430 103.964 37.590 1.00 103.67 ? 449 HOH A O 1 HETATM 3127 O O . HOH C 3 . ? 47.744 78.445 35.743 1.00 82.58 ? 450 HOH A O 1 HETATM 3128 O O . HOH C 3 . ? 12.083 84.635 7.004 1.00 85.68 ? 451 HOH A O 1 HETATM 3129 O O . HOH C 3 . ? 38.053 126.433 64.544 1.00 112.08 ? 452 HOH A O 1 HETATM 3130 O O . HOH C 3 . ? 19.258 100.587 23.340 1.00 117.47 ? 453 HOH A O 1 HETATM 3131 O O . HOH C 3 . ? 32.040 80.820 34.411 1.00 112.90 ? 454 HOH A O 1 HETATM 3132 O O . HOH C 3 . ? 23.003 81.266 42.392 1.00 100.95 ? 455 HOH A O 1 HETATM 3133 O O . HOH C 3 . ? 35.542 94.358 43.892 1.00 128.80 ? 456 HOH A O 1 HETATM 3134 O O . HOH C 3 . ? 44.668 92.204 28.200 1.00 95.24 ? 457 HOH A O 1 HETATM 3135 O O . HOH C 3 . ? 37.459 103.223 59.839 1.00 90.65 ? 458 HOH A O 1 HETATM 3136 O O . HOH C 3 . ? 26.830 67.716 7.609 1.00 87.22 ? 459 HOH A O 1 HETATM 3137 O O . HOH C 3 . ? 35.184 63.993 17.690 1.00 109.43 ? 460 HOH A O 1 HETATM 3138 O O . HOH C 3 . ? 31.249 87.967 50.317 1.00 72.51 ? 461 HOH A O 1 HETATM 3139 O O . HOH C 3 . ? 8.096 69.899 11.143 1.00 87.51 ? 462 HOH A O 1 HETATM 3140 O O . HOH C 3 . ? 10.780 63.841 37.074 1.00 92.88 ? 463 HOH A O 1 HETATM 3141 O O . HOH C 3 . ? 4.518 72.710 32.275 1.00 93.79 ? 464 HOH A O 1 HETATM 3142 O O . HOH C 3 . ? 20.564 120.198 58.723 1.00 85.28 ? 465 HOH A O 1 HETATM 3143 O O . HOH C 3 . ? 56.616 78.645 36.248 1.00 83.55 ? 466 HOH A O 1 HETATM 3144 O O . HOH C 3 . ? 4.542 62.972 13.028 1.00 100.04 ? 467 HOH A O 1 HETATM 3145 O O . HOH C 3 . ? 3.944 72.162 15.992 1.00 80.53 ? 468 HOH A O 1 HETATM 3146 O O . HOH C 3 . ? 48.832 126.124 64.389 1.00 81.81 ? 469 HOH A O 1 HETATM 3147 O O . HOH C 3 . ? 49.653 123.368 52.624 1.00 91.92 ? 470 HOH A O 1 HETATM 3148 O O . HOH C 3 . ? 25.473 98.660 44.496 1.00 80.68 ? 471 HOH A O 1 HETATM 3149 O O . HOH C 3 . ? 38.205 101.142 42.468 1.00 123.84 ? 472 HOH A O 1 HETATM 3150 O O . HOH C 3 . ? 28.023 73.049 45.708 1.00 109.45 ? 473 HOH A O 1 HETATM 3151 O O . HOH C 3 . ? 11.312 71.928 34.895 1.00 80.46 ? 474 HOH A O 1 HETATM 3152 O O . HOH C 3 . ? 50.234 121.066 56.304 1.00 83.15 ? 475 HOH A O 1 HETATM 3153 O O . HOH C 3 . ? 37.135 92.112 52.858 1.00 71.18 ? 476 HOH A O 1 HETATM 3154 O O . HOH C 3 . ? 16.085 76.028 9.741 1.00 108.31 ? 477 HOH A O 1 HETATM 3155 O O . HOH C 3 . ? 6.857 100.952 35.767 1.00 105.98 ? 478 HOH A O 1 HETATM 3156 O O . HOH C 3 . ? 41.766 101.636 35.849 1.00 83.67 ? 479 HOH A O 1 HETATM 3157 O O . HOH C 3 . ? 16.211 70.342 40.052 1.00 97.00 ? 480 HOH A O 1 HETATM 3158 O O . HOH C 3 . ? 23.319 100.992 50.402 1.00 84.62 ? 481 HOH A O 1 HETATM 3159 O O . HOH C 3 . ? 15.122 49.579 16.467 1.00 89.14 ? 482 HOH A O 1 HETATM 3160 O O . HOH C 3 . ? 37.023 94.738 49.594 1.00 112.36 ? 483 HOH A O 1 HETATM 3161 O O . HOH C 3 . ? -0.112 67.347 9.201 1.00 93.24 ? 484 HOH A O 1 HETATM 3162 O O . HOH C 3 . ? 8.522 62.439 16.657 1.00 80.74 ? 485 HOH A O 1 HETATM 3163 O O . HOH C 3 . ? 19.247 77.108 7.848 1.00 92.90 ? 486 HOH A O 1 HETATM 3164 O O . HOH C 3 . ? 2.548 85.366 34.029 1.00 81.27 ? 487 HOH A O 1 HETATM 3165 O O . HOH C 3 . ? 57.037 121.014 70.967 1.00 111.26 ? 488 HOH A O 1 HETATM 3166 O O . HOH C 3 . ? 48.230 118.263 69.362 1.00 82.22 ? 489 HOH A O 1 HETATM 3167 O O . HOH C 3 . ? 26.077 100.423 22.647 1.00 78.84 ? 490 HOH A O 1 HETATM 3168 O O . HOH C 3 . ? 30.441 68.594 44.369 1.00 118.98 ? 491 HOH A O 1 HETATM 3169 O O . HOH C 3 . ? 11.676 108.110 41.405 1.00 95.38 ? 492 HOH A O 1 HETATM 3170 O O . HOH C 3 . ? 16.947 43.469 29.369 1.00 85.34 ? 493 HOH A O 1 HETATM 3171 O O . HOH C 3 . ? 3.323 72.323 26.356 1.00 89.89 ? 494 HOH A O 1 HETATM 3172 O O . HOH C 3 . ? 36.856 109.859 43.083 1.00 135.83 ? 495 HOH A O 1 HETATM 3173 O O . HOH C 3 . ? 22.368 89.402 25.572 1.00 50.53 ? 496 HOH A O 1 HETATM 3174 O O . HOH C 3 . ? -2.412 77.706 31.090 1.00 66.34 ? 497 HOH A O 1 HETATM 3175 O O . HOH C 3 . ? 30.603 94.989 42.338 1.00 59.67 ? 498 HOH A O 1 HETATM 3176 O O . HOH C 3 . ? 23.970 77.511 21.590 1.00 90.18 ? 499 HOH A O 1 HETATM 3177 O O . HOH C 3 . ? 18.499 61.527 12.362 1.00 72.85 ? 500 HOH A O 1 HETATM 3178 O O . HOH C 3 . ? 44.152 77.574 44.145 1.00 72.26 ? 501 HOH A O 1 HETATM 3179 O O . HOH C 3 . ? 24.189 90.769 36.882 1.00 72.84 ? 502 HOH A O 1 HETATM 3180 O O . HOH C 3 . ? 34.658 75.263 25.178 1.00 88.37 ? 503 HOH A O 1 HETATM 3181 O O . HOH C 3 . ? 17.921 87.529 39.886 1.00 64.19 ? 504 HOH A O 1 HETATM 3182 O O . HOH C 3 . ? 40.743 109.761 36.191 1.00 85.80 ? 505 HOH A O 1 HETATM 3183 O O . HOH C 3 . ? 5.615 78.555 24.835 1.00 70.49 ? 506 HOH A O 1 HETATM 3184 O O . HOH C 3 . ? 40.865 121.620 71.030 1.00 87.27 ? 507 HOH A O 1 HETATM 3185 O O . HOH C 3 . ? 53.299 83.062 47.206 1.00 74.27 ? 508 HOH A O 1 HETATM 3186 O O . HOH C 3 . ? 35.003 88.070 49.695 1.00 62.17 ? 509 HOH A O 1 HETATM 3187 O O . HOH C 3 . ? 49.323 84.892 56.465 1.00 72.80 ? 510 HOH A O 1 HETATM 3188 O O . HOH C 3 . ? 33.975 76.605 29.926 1.00 64.55 ? 511 HOH A O 1 HETATM 3189 O O . HOH C 3 . ? 1.627 63.395 28.972 1.00 86.14 ? 512 HOH A O 1 HETATM 3190 O O . HOH C 3 . ? 23.398 84.168 21.568 1.00 67.05 ? 513 HOH A O 1 HETATM 3191 O O . HOH C 3 . ? 41.039 101.991 41.635 1.00 65.31 ? 514 HOH A O 1 HETATM 3192 O O . HOH C 3 . ? 40.198 107.107 43.005 1.00 78.88 ? 515 HOH A O 1 HETATM 3193 O O . HOH C 3 . ? 36.018 90.243 42.285 1.00 66.50 ? 516 HOH A O 1 HETATM 3194 O O . HOH C 3 . ? 58.068 89.139 48.878 1.00 88.26 ? 517 HOH A O 1 HETATM 3195 O O . HOH C 3 . ? 0.815 96.167 41.461 1.00 110.08 ? 518 HOH A O 1 HETATM 3196 O O . HOH C 3 . ? 20.591 56.929 6.827 1.00 83.24 ? 519 HOH A O 1 HETATM 3197 O O . HOH C 3 . ? 29.720 81.164 26.559 1.00 106.19 ? 520 HOH A O 1 HETATM 3198 O O . HOH C 3 . ? 53.998 81.448 51.979 1.00 67.51 ? 521 HOH A O 1 HETATM 3199 O O . HOH C 3 . ? 19.691 116.869 61.213 1.00 107.48 ? 522 HOH A O 1 HETATM 3200 O O . HOH C 3 . ? 36.492 103.458 43.126 1.00 61.44 ? 523 HOH A O 1 HETATM 3201 O O . HOH C 3 . ? 38.150 95.584 48.094 1.00 67.89 ? 524 HOH A O 1 HETATM 3202 O O . HOH C 3 . ? 3.242 66.785 18.481 1.00 84.15 ? 525 HOH A O 1 HETATM 3203 O O . HOH C 3 . ? 35.912 89.319 46.523 1.00 97.27 ? 526 HOH A O 1 HETATM 3204 O O . HOH C 3 . ? 28.199 68.800 19.367 1.00 74.33 ? 527 HOH A O 1 HETATM 3205 O O . HOH C 3 . ? 11.913 65.112 22.578 1.00 69.43 ? 528 HOH A O 1 HETATM 3206 O O . HOH C 3 . ? 53.314 99.052 46.808 1.00 88.08 ? 529 HOH A O 1 HETATM 3207 O O . HOH C 3 . ? 44.999 76.456 35.767 1.00 98.30 ? 530 HOH A O 1 HETATM 3208 O O . HOH C 3 . ? 28.175 71.291 43.979 1.00 56.68 ? 531 HOH A O 1 HETATM 3209 O O . HOH C 3 . ? 21.836 91.482 26.571 1.00 76.68 ? 532 HOH A O 1 HETATM 3210 O O . HOH C 3 . ? 37.148 90.137 44.374 1.00 78.59 ? 533 HOH A O 1 HETATM 3211 O O . HOH C 3 . ? 23.499 87.958 24.126 1.00 63.16 ? 534 HOH A O 1 HETATM 3212 O O . HOH C 3 . ? 34.882 81.660 37.629 1.00 75.44 ? 535 HOH A O 1 HETATM 3213 O O . HOH C 3 . ? 29.617 96.969 50.523 1.00 91.39 ? 536 HOH A O 1 HETATM 3214 O O . HOH C 3 . ? 9.613 59.562 9.361 1.00 94.16 ? 537 HOH A O 1 HETATM 3215 O O . HOH C 3 . ? 45.995 86.490 32.310 1.00 79.14 ? 538 HOH A O 1 HETATM 3216 O O . HOH C 3 . ? 21.805 72.472 21.144 1.00 82.15 ? 539 HOH A O 1 HETATM 3217 O O . HOH C 3 . ? 36.452 93.828 55.060 1.00 65.92 ? 540 HOH A O 1 HETATM 3218 O O . HOH C 3 . ? 31.466 57.904 17.236 1.00 52.35 ? 541 HOH A O 1 HETATM 3219 O O . HOH C 3 . ? 3.284 79.020 23.812 1.00 73.47 ? 542 HOH A O 1 HETATM 3220 O O . HOH C 3 . ? 23.852 76.812 26.524 1.00 64.05 ? 543 HOH A O 1 HETATM 3221 O O . HOH C 3 . ? 49.349 103.651 69.067 1.00 73.28 ? 544 HOH A O 1 HETATM 3222 O O . HOH C 3 . ? 58.963 96.827 48.464 1.00 80.03 ? 545 HOH A O 1 HETATM 3223 O O . HOH C 3 . ? 34.042 70.449 14.223 1.00 79.85 ? 546 HOH A O 1 HETATM 3224 O O . HOH C 3 . ? 28.194 92.783 52.402 1.00 89.09 ? 547 HOH A O 1 HETATM 3225 O O . HOH C 3 . ? 18.039 63.988 36.294 1.00 90.58 ? 548 HOH A O 1 HETATM 3226 O O . HOH C 3 . ? 28.621 107.060 29.524 1.00 75.38 ? 549 HOH A O 1 HETATM 3227 O O . HOH C 3 . ? 2.252 88.845 33.076 1.00 95.13 ? 550 HOH A O 1 HETATM 3228 O O . HOH C 3 . ? 5.524 66.466 32.028 1.00 98.04 ? 551 HOH A O 1 HETATM 3229 O O . HOH C 3 . ? 23.540 79.994 21.726 1.00 81.23 ? 552 HOH A O 1 HETATM 3230 O O . HOH C 3 . ? 35.724 112.217 38.645 1.00 83.95 ? 553 HOH A O 1 HETATM 3231 O O . HOH C 3 . ? 18.876 54.758 31.334 1.00 89.40 ? 554 HOH A O 1 HETATM 3232 O O . HOH C 3 . ? 27.311 101.173 26.372 1.00 99.55 ? 555 HOH A O 1 HETATM 3233 O O . HOH C 3 . ? 51.386 87.051 36.228 1.00 88.01 ? 556 HOH A O 1 HETATM 3234 O O . HOH C 3 . ? 43.846 78.702 35.181 1.00 53.84 ? 557 HOH A O 1 HETATM 3235 O O . HOH C 3 . ? 56.880 85.215 53.916 1.00 91.21 ? 558 HOH A O 1 HETATM 3236 O O . HOH C 3 . ? 34.488 102.555 39.428 1.00 87.64 ? 559 HOH A O 1 HETATM 3237 O O . HOH C 3 . ? 53.725 85.771 36.989 1.00 83.08 ? 560 HOH A O 1 HETATM 3238 O O . HOH C 3 . ? 38.453 103.868 44.518 1.00 71.04 ? 561 HOH A O 1 HETATM 3239 O O . HOH C 3 . ? 7.492 66.783 17.602 1.00 102.16 ? 562 HOH A O 1 HETATM 3240 O O . HOH C 3 . ? 28.894 107.116 25.946 1.00 88.25 ? 563 HOH A O 1 HETATM 3241 O O . HOH C 3 . ? 52.083 114.093 54.172 1.00 78.80 ? 564 HOH A O 1 HETATM 3242 O O . HOH C 3 . ? 35.710 72.987 47.742 1.00 70.46 ? 565 HOH A O 1 HETATM 3243 O O . HOH C 3 . ? 8.781 107.413 54.256 1.00 94.81 ? 566 HOH A O 1 HETATM 3244 O O . HOH C 3 . ? 26.382 82.935 28.786 1.00 54.85 ? 567 HOH A O 1 HETATM 3245 O O . HOH C 3 . ? 35.489 96.736 38.616 1.00 50.99 ? 568 HOH A O 1 HETATM 3246 O O . HOH C 3 . ? 42.763 80.388 51.661 1.00 52.30 ? 569 HOH A O 1 HETATM 3247 O O . HOH C 3 . ? 31.281 60.681 16.959 1.00 71.91 ? 570 HOH A O 1 HETATM 3248 O O . HOH C 3 . ? 36.201 93.600 41.411 1.00 72.83 ? 571 HOH A O 1 HETATM 3249 O O . HOH C 3 . ? 1.064 79.973 34.665 1.00 74.57 ? 572 HOH A O 1 HETATM 3250 O O . HOH C 3 . ? 20.565 52.081 7.256 1.00 67.04 ? 573 HOH A O 1 HETATM 3251 O O . HOH C 3 . ? 13.649 50.572 32.716 1.00 85.64 ? 574 HOH A O 1 HETATM 3252 O O . HOH C 3 . ? 28.441 71.202 10.771 1.00 77.00 ? 575 HOH A O 1 HETATM 3253 O O . HOH C 3 . ? 50.004 94.000 30.875 1.00 82.21 ? 576 HOH A O 1 HETATM 3254 O O . HOH C 3 . ? 50.657 81.808 49.577 1.00 71.76 ? 577 HOH A O 1 HETATM 3255 O O . HOH C 3 . ? 51.674 100.332 37.934 1.00 77.38 ? 578 HOH A O 1 HETATM 3256 O O . HOH C 3 . ? 37.538 78.734 30.184 1.00 58.25 ? 579 HOH A O 1 HETATM 3257 O O . HOH C 3 . ? 13.227 59.728 14.736 1.00 81.99 ? 580 HOH A O 1 HETATM 3258 O O . HOH C 3 . ? 26.764 78.541 27.571 1.00 82.37 ? 581 HOH A O 1 HETATM 3259 O O . HOH C 3 . ? 33.060 69.522 18.456 1.00 89.58 ? 582 HOH A O 1 HETATM 3260 O O . HOH C 3 . ? 33.173 82.665 35.937 1.00 66.08 ? 583 HOH A O 1 HETATM 3261 O O . HOH C 3 . ? 13.629 95.520 18.186 1.00 78.62 ? 584 HOH A O 1 HETATM 3262 O O . HOH C 3 . ? 11.530 100.757 42.867 1.00 70.85 ? 585 HOH A O 1 HETATM 3263 O O . HOH C 3 . ? 25.050 81.003 38.384 1.00 88.83 ? 586 HOH A O 1 HETATM 3264 O O . HOH C 3 . ? 22.349 56.906 37.575 1.00 75.39 ? 587 HOH A O 1 HETATM 3265 O O . HOH C 3 . ? 13.210 68.804 35.295 1.00 77.56 ? 588 HOH A O 1 HETATM 3266 O O . HOH C 3 . ? 34.575 128.108 50.012 1.00 75.71 ? 589 HOH A O 1 HETATM 3267 O O . HOH C 3 . ? 58.065 99.250 47.756 1.00 81.23 ? 590 HOH A O 1 HETATM 3268 O O . HOH C 3 . ? 27.496 121.950 64.732 1.00 64.00 ? 591 HOH A O 1 HETATM 3269 O O . HOH C 3 . ? -3.609 97.665 30.907 1.00 86.67 ? 592 HOH A O 1 HETATM 3270 O O . HOH C 3 . ? 22.439 88.006 37.721 1.00 88.47 ? 593 HOH A O 1 HETATM 3271 O O . HOH C 3 . ? 35.931 111.012 41.140 1.00 85.51 ? 594 HOH A O 1 HETATM 3272 O O . HOH C 3 . ? 14.602 67.697 3.139 1.00 81.20 ? 595 HOH A O 1 HETATM 3273 O O . HOH C 3 . ? 28.122 81.391 33.789 1.00 80.01 ? 596 HOH A O 1 HETATM 3274 O O . HOH C 3 . ? 23.672 81.261 12.599 1.00 89.89 ? 597 HOH A O 1 HETATM 3275 O O . HOH C 3 . ? 33.679 93.669 45.374 1.00 94.84 ? 598 HOH A O 1 HETATM 3276 O O . HOH C 3 . ? 25.579 108.778 55.793 1.00 77.81 ? 599 HOH A O 1 HETATM 3277 O O . HOH C 3 . ? 14.749 89.099 37.777 1.00 75.88 ? 600 HOH A O 1 HETATM 3278 O O . HOH C 3 . ? 6.644 101.148 25.238 1.00 79.72 ? 601 HOH A O 1 HETATM 3279 O O . HOH C 3 . ? 10.223 77.100 8.917 1.00 71.15 ? 602 HOH A O 1 HETATM 3280 O O . HOH C 3 . ? 13.198 58.357 18.777 1.00 78.02 ? 603 HOH A O 1 HETATM 3281 O O . HOH C 3 . ? 30.429 84.599 37.839 1.00 68.70 ? 604 HOH A O 1 HETATM 3282 O O . HOH C 3 . ? 33.196 65.685 13.988 1.00 75.13 ? 605 HOH A O 1 HETATM 3283 O O . HOH C 3 . ? 12.568 85.747 9.581 1.00 92.44 ? 606 HOH A O 1 HETATM 3284 O O . HOH C 3 . ? 15.646 93.203 17.369 1.00 67.70 ? 607 HOH A O 1 HETATM 3285 O O . HOH C 3 . ? 54.153 94.848 39.854 1.00 90.64 ? 608 HOH A O 1 HETATM 3286 O O . HOH C 3 . ? 3.982 103.072 28.958 1.00 86.12 ? 609 HOH A O 1 HETATM 3287 O O . HOH C 3 . ? 53.128 120.360 66.770 1.00 94.10 ? 610 HOH A O 1 HETATM 3288 O O . HOH C 3 . ? 21.009 100.011 21.867 1.00 95.61 ? 611 HOH A O 1 HETATM 3289 O O . HOH C 3 . ? 6.938 87.368 9.059 1.00 85.02 ? 612 HOH A O 1 HETATM 3290 O O . HOH C 3 . ? 12.151 53.580 25.772 1.00 76.83 ? 613 HOH A O 1 HETATM 3291 O O . HOH C 3 . ? 26.121 76.202 9.539 1.00 84.37 ? 614 HOH A O 1 HETATM 3292 O O . HOH C 3 . ? 4.270 59.236 22.759 1.00 110.28 ? 615 HOH A O 1 HETATM 3293 O O . HOH C 3 . ? 50.341 84.847 34.343 1.00 72.10 ? 616 HOH A O 1 HETATM 3294 O O . HOH C 3 . ? 6.946 64.343 21.386 1.00 69.36 ? 617 HOH A O 1 HETATM 3295 O O . HOH C 3 . ? 52.166 84.574 42.632 1.00 69.52 ? 618 HOH A O 1 HETATM 3296 O O . HOH C 3 . ? 1.320 63.559 24.296 1.00 102.82 ? 619 HOH A O 1 HETATM 3297 O O . HOH C 3 . ? 30.158 102.324 53.786 1.00 81.28 ? 620 HOH A O 1 HETATM 3298 O O . HOH C 3 . ? 32.183 87.285 41.434 1.00 80.99 ? 621 HOH A O 1 HETATM 3299 O O . HOH C 3 . ? 42.707 90.403 31.604 1.00 67.35 ? 622 HOH A O 1 HETATM 3300 O O . HOH C 3 . ? 50.531 118.402 69.942 1.00 72.90 ? 623 HOH A O 1 HETATM 3301 O O . HOH C 3 . ? 27.799 94.837 29.772 1.00 81.71 ? 624 HOH A O 1 HETATM 3302 O O . HOH C 3 . ? -0.838 89.881 30.266 1.00 86.05 ? 625 HOH A O 1 HETATM 3303 O O . HOH C 3 . ? 22.422 48.124 30.020 1.00 93.20 ? 626 HOH A O 1 HETATM 3304 O O . HOH C 3 . ? 47.976 80.126 52.051 1.00 82.60 ? 627 HOH A O 1 HETATM 3305 O O . HOH C 3 . ? 58.151 95.694 38.214 1.00 109.33 ? 628 HOH A O 1 HETATM 3306 O O . HOH C 3 . ? 39.177 75.359 49.336 1.00 80.33 ? 629 HOH A O 1 HETATM 3307 O O . HOH C 3 . ? 32.465 60.181 19.173 1.00 74.88 ? 630 HOH A O 1 HETATM 3308 O O . HOH C 3 . ? 35.873 91.800 39.550 1.00 74.41 ? 631 HOH A O 1 HETATM 3309 O O . HOH C 3 . ? 26.165 84.759 30.335 1.00 64.63 ? 632 HOH A O 1 HETATM 3310 O O . HOH C 3 . ? 44.005 104.067 38.465 1.00 77.98 ? 633 HOH A O 1 HETATM 3311 O O . HOH C 3 . ? 23.782 87.333 41.263 1.00 81.61 ? 634 HOH A O 1 HETATM 3312 O O . HOH C 3 . ? 43.285 108.358 36.644 1.00 82.88 ? 635 HOH A O 1 HETATM 3313 O O . HOH C 3 . ? 45.018 81.692 51.293 1.00 77.52 ? 636 HOH A O 1 HETATM 3314 O O . HOH C 3 . ? 55.730 82.024 39.510 1.00 74.74 ? 637 HOH A O 1 HETATM 3315 O O . HOH C 3 . ? 26.727 73.108 13.859 1.00 99.15 ? 638 HOH A O 1 HETATM 3316 O O . HOH C 3 . ? 34.732 110.040 36.818 1.00 106.05 ? 639 HOH A O 1 HETATM 3317 O O . HOH C 3 . ? 4.927 68.257 13.725 1.00 93.77 ? 640 HOH A O 1 HETATM 3318 O O . HOH C 3 . ? 19.609 89.095 43.105 1.00 71.64 ? 641 HOH A O 1 HETATM 3319 O O . HOH C 3 . ? 6.480 90.729 10.203 1.00 77.04 ? 642 HOH A O 1 HETATM 3320 O O . HOH C 3 . ? 36.438 126.994 62.549 1.00 69.78 ? 643 HOH A O 1 HETATM 3321 O O . HOH C 3 . ? 39.154 81.738 28.593 1.00 107.96 ? 644 HOH A O 1 HETATM 3322 O O . HOH C 3 . ? 22.285 53.445 6.503 1.00 81.95 ? 645 HOH A O 1 HETATM 3323 O O . HOH C 3 . ? 28.393 68.613 14.076 1.00 85.70 ? 646 HOH A O 1 HETATM 3324 O O . HOH C 3 . ? 9.899 97.040 20.891 1.00 90.85 ? 647 HOH A O 1 HETATM 3325 O O . HOH C 3 . ? 35.590 84.273 34.382 1.00 99.52 ? 648 HOH A O 1 HETATM 3326 O O . HOH C 3 . ? 16.857 61.728 5.159 1.00 89.51 ? 649 HOH A O 1 HETATM 3327 O O . HOH C 3 . ? 26.574 93.644 45.335 1.00 88.86 ? 650 HOH A O 1 HETATM 3328 O O . HOH C 3 . ? 60.678 98.106 46.432 1.00 78.34 ? 651 HOH A O 1 HETATM 3329 O O . HOH C 3 . ? 34.804 72.355 25.090 1.00 89.98 ? 652 HOH A O 1 HETATM 3330 O O . HOH C 3 . ? 22.498 78.800 10.874 1.00 118.21 ? 653 HOH A O 1 HETATM 3331 O O . HOH C 3 . ? 17.746 95.823 43.848 1.00 74.72 ? 654 HOH A O 1 HETATM 3332 O O . HOH C 3 . ? 19.298 95.055 45.623 1.00 77.29 ? 655 HOH A O 1 HETATM 3333 O O . HOH C 3 . ? 30.006 96.214 38.782 1.00 88.93 ? 656 HOH A O 1 HETATM 3334 O O . HOH C 3 . ? 28.896 93.194 32.179 1.00 76.83 ? 657 HOH A O 1 HETATM 3335 O O . HOH C 3 . ? 38.898 102.523 33.964 1.00 92.33 ? 658 HOH A O 1 HETATM 3336 O O . HOH C 3 . ? 34.216 95.172 49.093 1.00 103.45 ? 659 HOH A O 1 HETATM 3337 O O . HOH C 3 . ? 22.909 64.219 4.638 1.00 87.76 ? 660 HOH A O 1 HETATM 3338 O O . HOH C 3 . ? 52.042 101.156 35.253 1.00 79.59 ? 661 HOH A O 1 HETATM 3339 O O . HOH C 3 . ? 29.732 83.291 43.425 1.00 85.05 ? 662 HOH A O 1 HETATM 3340 O O . HOH C 3 . ? 6.267 67.229 37.146 1.00 102.00 ? 663 HOH A O 1 HETATM 3341 O O . HOH C 3 . ? 33.750 131.045 49.381 1.00 69.80 ? 664 HOH A O 1 HETATM 3342 O O . HOH C 3 . ? 17.447 57.854 6.465 1.00 80.79 ? 665 HOH A O 1 HETATM 3343 O O . HOH C 3 . ? 28.811 76.246 11.226 1.00 100.13 ? 666 HOH A O 1 HETATM 3344 O O . HOH C 3 . ? 12.544 66.732 3.780 1.00 98.76 ? 667 HOH A O 1 HETATM 3345 O O . HOH C 3 . ? 40.937 75.573 30.181 1.00 84.31 ? 668 HOH A O 1 HETATM 3346 O O . HOH C 3 . ? 15.779 61.158 9.662 1.00 98.57 ? 669 HOH A O 1 HETATM 3347 O O . HOH C 3 . ? 43.398 123.756 72.421 1.00 65.86 ? 670 HOH A O 1 HETATM 3348 O O . HOH C 3 . ? 60.470 87.762 46.875 1.00 86.84 ? 671 HOH A O 1 HETATM 3349 O O . HOH C 3 . ? 3.898 78.344 19.083 1.00 62.56 ? 672 HOH A O 1 HETATM 3350 O O . HOH C 3 . ? 28.057 81.685 31.474 1.00 81.78 ? 673 HOH A O 1 HETATM 3351 O O . HOH C 3 . ? 20.399 104.458 52.814 1.00 76.33 ? 674 HOH A O 1 HETATM 3352 O O . HOH C 3 . ? 31.434 89.779 44.584 1.00 98.40 ? 675 HOH A O 1 HETATM 3353 O O . HOH C 3 . ? 49.815 79.934 50.377 1.00 89.79 ? 676 HOH A O 1 HETATM 3354 O O . HOH C 3 . ? 32.112 96.510 46.250 1.00 76.75 ? 677 HOH A O 1 HETATM 3355 O O . HOH C 3 . ? 24.076 82.173 20.212 1.00 83.44 ? 678 HOH A O 1 HETATM 3356 O O . HOH C 3 . ? 9.654 91.772 10.845 1.00 100.22 ? 679 HOH A O 1 HETATM 3357 O O . HOH C 3 . ? 21.949 121.564 61.345 1.00 80.19 ? 680 HOH A O 1 HETATM 3358 O O . HOH C 3 . ? 46.375 127.759 71.671 1.00 70.32 ? 681 HOH A O 1 HETATM 3359 O O . HOH C 3 . ? -1.067 74.468 38.286 1.00 76.75 ? 682 HOH A O 1 HETATM 3360 O O . HOH C 3 . ? 33.419 99.978 34.941 1.00 78.18 ? 683 HOH A O 1 HETATM 3361 O O . HOH C 3 . ? 34.306 81.737 33.579 1.00 74.48 ? 684 HOH A O 1 HETATM 3362 O O . HOH C 3 . ? 0.828 84.868 31.513 1.00 84.31 ? 685 HOH A O 1 HETATM 3363 O O . HOH C 3 . ? 15.034 44.494 26.709 1.00 88.32 ? 686 HOH A O 1 HETATM 3364 O O . HOH C 3 . ? 12.550 94.032 13.600 1.00 75.41 ? 687 HOH A O 1 HETATM 3365 O O . HOH C 3 . ? 31.006 78.987 27.903 1.00 80.43 ? 688 HOH A O 1 HETATM 3366 O O . HOH C 3 . ? 0.332 83.456 36.111 1.00 88.92 ? 689 HOH A O 1 HETATM 3367 O O . HOH C 3 . ? 44.457 92.382 30.740 1.00 79.22 ? 690 HOH A O 1 HETATM 3368 O O . HOH C 3 . ? 14.239 57.247 9.553 1.00 84.52 ? 691 HOH A O 1 HETATM 3369 O O . HOH C 3 . ? 3.506 63.927 20.863 1.00 82.46 ? 692 HOH A O 1 HETATM 3370 O O . HOH C 3 . ? -0.302 76.324 43.041 1.00 79.08 ? 693 HOH A O 1 HETATM 3371 O O . HOH C 3 . ? 53.390 112.500 47.382 1.00 77.28 ? 694 HOH A O 1 HETATM 3372 O O . HOH C 3 . ? 63.398 99.699 47.351 1.00 71.76 ? 695 HOH A O 1 HETATM 3373 O O . HOH C 3 . ? 39.978 73.289 42.340 1.00 108.92 ? 696 HOH A O 1 HETATM 3374 O O . HOH C 3 . ? 40.262 73.158 47.435 1.00 80.47 ? 697 HOH A O 1 HETATM 3375 O O . HOH C 3 . ? 12.467 78.985 39.512 1.00 66.92 ? 698 HOH A O 1 HETATM 3376 O O . HOH C 3 . ? 5.832 70.058 12.153 1.00 84.66 ? 699 HOH A O 1 HETATM 3377 O O . HOH C 3 . ? 19.209 64.940 38.647 1.00 81.46 ? 700 HOH A O 1 HETATM 3378 O O . HOH C 3 . ? 22.882 123.526 58.006 1.00 94.14 ? 701 HOH A O 1 HETATM 3379 O O . HOH C 3 . ? 60.887 85.857 45.231 1.00 84.48 ? 702 HOH A O 1 HETATM 3380 O O . HOH C 3 . ? 58.209 97.405 43.463 1.00 89.56 ? 703 HOH A O 1 HETATM 3381 O O . HOH C 3 . ? 25.679 123.233 55.569 1.00 81.48 ? 704 HOH A O 1 HETATM 3382 O O . HOH C 3 . ? 47.025 91.565 33.378 1.00 78.90 ? 705 HOH A O 1 HETATM 3383 O O . HOH C 3 . ? 27.762 94.869 38.921 1.00 88.19 ? 706 HOH A O 1 HETATM 3384 O O . HOH C 3 . ? 29.665 122.726 66.656 1.00 97.29 ? 707 HOH A O 1 HETATM 3385 O O . HOH C 3 . ? 9.964 69.800 38.644 1.00 76.61 ? 708 HOH A O 1 HETATM 3386 O O . HOH C 3 . ? 11.588 55.631 10.613 1.00 91.99 ? 709 HOH A O 1 HETATM 3387 O O . HOH C 3 . ? 25.753 94.437 28.061 1.00 99.88 ? 710 HOH A O 1 HETATM 3388 O O . HOH C 3 . ? 44.804 104.935 34.600 1.00 75.23 ? 711 HOH A O 1 HETATM 3389 O O . HOH C 3 . ? 53.461 80.849 35.958 1.00 74.29 ? 712 HOH A O 1 HETATM 3390 O O . HOH C 3 . ? 5.615 96.814 17.313 1.00 87.49 ? 713 HOH A O 1 HETATM 3391 O O . HOH C 3 . ? 22.260 87.866 44.433 1.00 92.69 ? 714 HOH A O 1 HETATM 3392 O O . HOH C 3 . ? -1.618 68.551 7.693 1.00 109.14 ? 715 HOH A O 1 HETATM 3393 O O . HOH C 3 . ? 55.680 95.138 31.238 1.00 91.70 ? 716 HOH A O 1 HETATM 3394 O O . HOH C 3 . ? 33.164 131.842 52.878 1.00 83.47 ? 717 HOH A O 1 HETATM 3395 O O . HOH C 3 . ? 21.103 46.391 24.752 1.00 72.44 ? 718 HOH A O 1 HETATM 3396 O O . HOH C 3 . ? 24.615 46.042 32.885 1.00 86.84 ? 719 HOH A O 1 HETATM 3397 O O . HOH C 3 . ? 62.356 95.463 44.043 1.00 73.10 ? 720 HOH A O 1 HETATM 3398 O O . HOH C 3 . ? 48.607 79.907 45.421 1.00 69.60 ? 721 HOH A O 1 HETATM 3399 O O . HOH C 3 . ? 42.861 113.755 37.242 1.00 89.18 ? 722 HOH A O 1 HETATM 3400 O O . HOH C 3 . ? -0.350 65.591 11.681 1.00 111.46 ? 723 HOH A O 1 HETATM 3401 O O . HOH C 3 . ? 2.552 89.358 36.298 1.00 88.48 ? 724 HOH A O 1 HETATM 3402 O O . HOH C 3 . ? 24.088 76.821 6.576 1.00 80.38 ? 725 HOH A O 1 HETATM 3403 O O . HOH C 3 . ? 33.834 86.953 52.554 1.00 86.84 ? 726 HOH A O 1 HETATM 3404 O O . HOH C 3 . ? 37.894 114.379 70.886 1.00 97.81 ? 727 HOH A O 1 HETATM 3405 O O . HOH C 3 . ? 60.856 112.828 57.715 1.00 88.25 ? 728 HOH A O 1 HETATM 3406 O O . HOH C 3 . ? 27.658 124.934 52.788 1.00 91.17 ? 729 HOH A O 1 HETATM 3407 O O . HOH C 3 . ? 21.881 45.234 31.413 1.00 88.91 ? 730 HOH A O 1 HETATM 3408 O O . HOH C 3 . ? 38.070 92.261 33.536 1.00 88.48 ? 731 HOH A O 1 HETATM 3409 O O . HOH C 3 . ? 4.943 64.466 26.997 1.00 85.88 ? 732 HOH A O 1 HETATM 3410 O O . HOH C 3 . ? 32.479 92.234 31.717 1.00 91.91 ? 733 HOH A O 1 HETATM 3411 O O . HOH C 3 . ? 36.208 130.014 51.275 1.00 76.81 ? 734 HOH A O 1 HETATM 3412 O O . HOH C 3 . ? 41.536 95.459 50.527 1.00 85.44 ? 735 HOH A O 1 HETATM 3413 O O . HOH C 3 . ? 28.610 102.616 31.083 1.00 83.23 ? 736 HOH A O 1 HETATM 3414 O O . HOH C 3 . ? 18.217 77.253 40.663 1.00 74.22 ? 737 HOH A O 1 HETATM 3415 O O . HOH C 3 . ? 10.945 79.017 33.359 1.00 93.47 ? 738 HOH A O 1 HETATM 3416 O O . HOH C 3 . ? 29.690 74.755 45.346 1.00 73.03 ? 739 HOH A O 1 HETATM 3417 O O . HOH C 3 . ? 30.300 70.978 44.838 1.00 77.59 ? 740 HOH A O 1 HETATM 3418 O O . HOH C 3 . ? 38.276 73.261 48.808 1.00 89.04 ? 741 HOH A O 1 HETATM 3419 O O . HOH C 3 . ? 16.483 72.033 38.519 1.00 76.16 ? 742 HOH A O 1 HETATM 3420 O O . HOH C 3 . ? 56.970 93.117 46.760 1.00 94.86 ? 743 HOH A O 1 HETATM 3421 O O . HOH C 3 . ? 31.601 68.031 35.176 1.00 84.45 ? 744 HOH A O 1 HETATM 3422 O O . HOH C 3 . ? 49.719 85.634 42.702 1.00 80.05 ? 745 HOH A O 1 HETATM 3423 O O . HOH C 3 . ? 10.693 90.078 18.167 1.00 90.77 ? 746 HOH A O 1 HETATM 3424 O O . HOH C 3 . ? 23.427 74.031 23.256 1.00 75.19 ? 747 HOH A O 1 HETATM 3425 O O . HOH C 3 . ? 30.352 103.540 49.530 1.00 82.09 ? 748 HOH A O 1 HETATM 3426 O O . HOH C 3 . ? 45.862 78.269 37.692 1.00 83.15 ? 749 HOH A O 1 HETATM 3427 O O . HOH C 3 . ? 29.999 63.837 22.761 1.00 99.36 ? 750 HOH A O 1 HETATM 3428 O O . HOH C 3 . ? 26.220 79.805 34.645 1.00 69.70 ? 751 HOH A O 1 HETATM 3429 O O . HOH C 3 . ? 32.868 108.423 35.627 1.00 84.80 ? 752 HOH A O 1 HETATM 3430 O O . HOH C 3 . ? 51.106 84.174 49.705 1.00 101.60 ? 753 HOH A O 1 HETATM 3431 O O . HOH C 3 . ? 36.622 100.542 40.304 1.00 88.64 ? 754 HOH A O 1 HETATM 3432 O O . HOH C 3 . ? 11.141 58.315 10.709 1.00 109.99 ? 755 HOH A O 1 HETATM 3433 O O . HOH C 3 . ? -7.756 76.852 27.379 1.00 97.00 ? 756 HOH A O 1 HETATM 3434 O O . HOH C 3 . ? 23.574 70.499 37.882 1.00 78.68 ? 757 HOH A O 1 HETATM 3435 O O . HOH C 3 . ? 32.862 77.520 46.959 1.00 71.41 ? 758 HOH A O 1 HETATM 3436 O O . HOH C 3 . ? 21.457 91.987 28.935 1.00 91.75 ? 759 HOH A O 1 HETATM 3437 O O . HOH C 3 . ? 41.693 119.632 50.086 1.00 113.67 ? 760 HOH A O 1 HETATM 3438 O O . HOH C 3 . ? 39.007 93.504 58.370 1.00 83.52 ? 761 HOH A O 1 HETATM 3439 O O . HOH C 3 . ? 36.597 94.161 45.580 1.00 72.61 ? 762 HOH A O 1 HETATM 3440 O O . HOH C 3 . ? 34.285 106.890 46.335 1.00 116.10 ? 763 HOH A O 1 HETATM 3441 O O . HOH C 3 . ? 29.921 59.283 16.186 1.00 75.93 ? 764 HOH A O 1 HETATM 3442 O O . HOH C 3 . ? 49.798 108.498 67.485 1.00 97.65 ? 765 HOH A O 1 HETATM 3443 O O . HOH C 3 . ? 41.640 114.389 40.749 1.00 78.84 ? 766 HOH A O 1 HETATM 3444 O O . HOH C 3 . ? 27.428 108.375 27.638 1.00 91.81 ? 767 HOH A O 1 HETATM 3445 O O . HOH C 3 . ? 55.889 98.935 43.519 1.00 89.52 ? 768 HOH A O 1 HETATM 3446 O O . HOH C 3 . ? 14.897 62.947 20.984 1.00 122.76 ? 769 HOH A O 1 HETATM 3447 O O . HOH C 3 . ? 28.439 104.168 55.566 1.00 104.03 ? 770 HOH A O 1 HETATM 3448 O O . HOH C 3 . ? -2.798 99.483 29.742 1.00 90.63 ? 771 HOH A O 1 HETATM 3449 O O . HOH C 3 . ? 35.602 109.784 60.609 1.00 105.84 ? 772 HOH A O 1 HETATM 3450 O O . HOH C 3 . ? 26.727 50.206 20.293 1.00 97.99 ? 773 HOH A O 1 HETATM 3451 O O . HOH C 3 . ? 31.723 64.728 38.845 1.00 82.57 ? 774 HOH A O 1 HETATM 3452 O O . HOH C 3 . ? 43.978 87.742 56.031 1.00 76.16 ? 775 HOH A O 1 HETATM 3453 O O . HOH C 3 . ? 27.433 73.291 26.053 1.00 87.09 ? 776 HOH A O 1 HETATM 3454 O O . HOH C 3 . ? 35.283 69.889 45.670 1.00 68.21 ? 777 HOH A O 1 HETATM 3455 O O . HOH C 3 . ? 37.065 90.187 47.942 1.00 107.25 ? 778 HOH A O 1 HETATM 3456 O O . HOH C 3 . ? 56.695 87.362 52.546 1.00 82.97 ? 779 HOH A O 1 HETATM 3457 O O . HOH C 3 . ? 34.658 97.519 48.787 1.00 129.37 ? 780 HOH A O 1 HETATM 3458 O O . HOH C 3 . ? 59.599 89.701 35.770 1.00 75.80 ? 781 HOH A O 1 HETATM 3459 O O . HOH C 3 . ? 33.655 95.630 40.091 1.00 78.34 ? 782 HOH A O 1 HETATM 3460 O O . HOH C 3 . ? 32.620 94.342 52.355 1.00 104.24 ? 783 HOH A O 1 HETATM 3461 O O . HOH C 3 . ? 37.006 78.954 34.692 1.00 92.04 ? 784 HOH A O 1 HETATM 3462 O O . HOH C 3 . ? 46.569 88.627 33.049 1.00 79.47 ? 785 HOH A O 1 HETATM 3463 O O . HOH C 3 . ? 37.598 121.735 45.419 1.00 97.19 ? 786 HOH A O 1 HETATM 3464 O O . HOH C 3 . ? 13.304 105.973 23.955 1.00 110.11 ? 787 HOH A O 1 HETATM 3465 O O . HOH C 3 . ? 21.566 61.643 9.740 1.00 100.35 ? 788 HOH A O 1 HETATM 3466 O O . HOH C 3 . ? 28.143 68.793 10.908 1.00 100.82 ? 789 HOH A O 1 HETATM 3467 O O . HOH C 3 . ? 38.070 65.233 40.518 1.00 98.14 ? 790 HOH A O 1 HETATM 3468 O O . HOH C 3 . ? 29.383 109.256 31.555 1.00 93.25 ? 791 HOH A O 1 HETATM 3469 O O . HOH C 3 . ? 51.560 89.187 56.930 1.00 87.15 ? 792 HOH A O 1 HETATM 3470 O O . HOH C 3 . ? 35.294 86.918 41.772 1.00 73.27 ? 793 HOH A O 1 HETATM 3471 O O . HOH C 3 . ? 54.905 84.209 44.293 1.00 91.60 ? 794 HOH A O 1 HETATM 3472 O O . HOH C 3 . ? 29.533 125.577 56.310 1.00 86.47 ? 795 HOH A O 1 HETATM 3473 O O . HOH C 3 . ? 39.904 92.540 52.089 1.00 68.07 ? 796 HOH A O 1 HETATM 3474 O O . HOH C 3 . ? 39.443 120.485 66.330 1.00 121.92 ? 797 HOH A O 1 HETATM 3475 O O . HOH C 3 . ? 42.277 101.196 47.571 1.00 85.19 ? 798 HOH A O 1 HETATM 3476 O O . HOH C 3 . ? 11.708 95.170 15.842 1.00 107.60 ? 799 HOH A O 1 HETATM 3477 O O . HOH C 3 . ? 54.980 96.908 46.811 1.00 102.39 ? 800 HOH A O 1 HETATM 3478 O O . HOH C 3 . ? 43.372 100.021 63.123 1.00 88.32 ? 801 HOH A O 1 HETATM 3479 O O . HOH C 3 . ? 21.673 106.245 51.920 1.00 105.78 ? 802 HOH A O 1 HETATM 3480 O O . HOH C 3 . ? 36.825 94.948 38.949 1.00 83.46 ? 803 HOH A O 1 HETATM 3481 O O . HOH C 3 . ? 63.916 101.531 44.734 1.00 93.76 ? 804 HOH A O 1 HETATM 3482 O O . HOH C 3 . ? 18.109 112.564 50.884 1.00 98.88 ? 805 HOH A O 1 HETATM 3483 O O . HOH C 3 . ? 41.543 71.515 49.623 1.00 81.32 ? 806 HOH A O 1 HETATM 3484 O O . HOH C 3 . ? 50.103 91.067 29.467 1.00 91.88 ? 807 HOH A O 1 HETATM 3485 O O . HOH C 3 . ? 34.651 92.470 49.212 1.00 94.98 ? 808 HOH A O 1 HETATM 3486 O O . HOH C 3 . ? 2.172 67.343 12.292 1.00 80.87 ? 809 HOH A O 1 HETATM 3487 O O . HOH C 3 . ? 15.373 99.062 42.496 1.00 85.14 ? 810 HOH A O 1 HETATM 3488 O O . HOH C 3 . ? 30.903 90.027 37.624 1.00 90.02 ? 811 HOH A O 1 HETATM 3489 O O . HOH C 3 . ? 25.714 72.745 34.141 1.00 126.19 ? 812 HOH A O 1 HETATM 3490 O O . HOH C 3 . ? 32.969 103.216 40.998 1.00 79.09 ? 813 HOH A O 1 HETATM 3491 O O . HOH C 3 . ? 14.655 104.578 53.920 1.00 87.26 ? 814 HOH A O 1 HETATM 3492 O O . HOH C 3 . ? 0.281 66.143 28.204 1.00 91.53 ? 815 HOH A O 1 HETATM 3493 O O . HOH C 3 . ? 21.353 90.354 40.145 1.00 102.67 ? 816 HOH A O 1 HETATM 3494 O O . HOH C 3 . ? 12.195 65.198 12.168 1.00 131.59 ? 817 HOH A O 1 HETATM 3495 O O . HOH C 3 . ? 37.240 98.297 37.260 1.00 69.70 ? 818 HOH A O 1 HETATM 3496 O O . HOH C 3 . ? 8.327 82.675 6.626 1.00 89.85 ? 819 HOH A O 1 HETATM 3497 O O . HOH C 3 . ? 35.936 85.207 53.721 1.00 82.41 ? 820 HOH A O 1 HETATM 3498 O O . HOH C 3 . ? 41.438 104.422 40.252 1.00 100.28 ? 821 HOH A O 1 HETATM 3499 O O . HOH C 3 . ? 3.439 86.288 38.926 1.00 97.51 ? 822 HOH A O 1 HETATM 3500 O O . HOH C 3 . ? 31.899 58.556 21.124 1.00 103.79 ? 823 HOH A O 1 HETATM 3501 O O . HOH C 3 . ? 12.853 96.485 21.747 1.00 102.61 ? 824 HOH A O 1 HETATM 3502 O O . HOH C 3 . ? 35.920 127.952 47.680 1.00 89.45 ? 825 HOH A O 1 HETATM 3503 O O . HOH C 3 . ? 51.895 124.368 62.970 1.00 87.45 ? 826 HOH A O 1 HETATM 3504 O O . HOH C 3 . ? 29.128 119.965 67.962 1.00 82.64 ? 827 HOH A O 1 HETATM 3505 O O . HOH C 3 . ? 19.801 50.420 31.627 1.00 100.74 ? 828 HOH A O 1 HETATM 3506 O O . HOH C 3 . ? 7.968 95.472 17.674 1.00 83.59 ? 829 HOH A O 1 HETATM 3507 O O . HOH C 3 . ? 12.368 67.580 38.039 1.00 77.31 ? 830 HOH A O 1 HETATM 3508 O O . HOH C 3 . ? 39.163 74.052 39.555 1.00 85.23 ? 831 HOH A O 1 HETATM 3509 O O . HOH C 3 . ? 16.866 78.734 8.234 1.00 97.55 ? 832 HOH A O 1 HETATM 3510 O O . HOH C 3 . ? 15.631 60.127 11.705 1.00 150.52 ? 833 HOH A O 1 HETATM 3511 O O . HOH C 3 . ? 26.008 85.402 33.912 1.00 89.17 ? 834 HOH A O 1 HETATM 3512 O O . HOH C 3 . ? 13.871 99.589 44.825 1.00 93.04 ? 835 HOH A O 1 HETATM 3513 O O . HOH C 3 . ? 59.050 83.132 44.094 1.00 81.56 ? 836 HOH A O 1 HETATM 3514 O O . HOH C 3 . ? 61.371 107.757 61.085 1.00 92.05 ? 837 HOH A O 1 HETATM 3515 O O . HOH C 3 . ? 40.933 77.504 42.350 1.00 85.74 ? 838 HOH A O 1 HETATM 3516 O O . HOH C 3 . ? 17.800 61.793 37.283 1.00 101.25 ? 839 HOH A O 1 HETATM 3517 O O . HOH C 3 . ? 4.219 106.591 27.468 1.00 110.23 ? 840 HOH A O 1 HETATM 3518 O O . HOH C 3 . ? 36.275 131.897 46.930 1.00 87.23 ? 841 HOH A O 1 HETATM 3519 O O . HOH C 3 . ? 17.127 98.657 23.338 1.00 95.15 ? 842 HOH A O 1 HETATM 3520 O O . HOH C 3 . ? 50.831 120.235 73.250 1.00 115.10 ? 843 HOH A O 1 HETATM 3521 O O . HOH C 3 . ? 33.140 66.062 16.428 1.00 73.05 ? 844 HOH A O 1 HETATM 3522 O O . HOH C 3 . ? 7.446 93.072 12.142 1.00 87.29 ? 845 HOH A O 1 HETATM 3523 O O . HOH C 3 . ? 29.589 116.088 62.175 1.00 83.68 ? 846 HOH A O 1 HETATM 3524 O O . HOH C 3 . ? 35.286 66.962 36.229 1.00 87.40 ? 847 HOH A O 1 HETATM 3525 O O . HOH C 3 . ? 35.881 103.862 57.363 1.00 76.26 ? 848 HOH A O 1 HETATM 3526 O O . HOH C 3 . ? 10.307 63.681 24.474 1.00 83.88 ? 849 HOH A O 1 HETATM 3527 O O . HOH C 3 . ? 32.071 96.121 43.850 1.00 100.52 ? 850 HOH A O 1 HETATM 3528 O O . HOH C 3 . ? 19.340 102.841 22.900 1.00 100.06 ? 851 HOH A O 1 HETATM 3529 O O . HOH C 3 . ? 22.714 89.817 27.628 1.00 110.33 ? 852 HOH A O 1 HETATM 3530 O O . HOH C 3 . ? 24.832 99.312 47.687 1.00 81.73 ? 853 HOH A O 1 HETATM 3531 O O . HOH C 3 . ? 44.637 126.444 50.819 1.00 94.32 ? 854 HOH A O 1 HETATM 3532 O O . HOH C 3 . ? 33.046 72.258 17.796 1.00 96.25 ? 855 HOH A O 1 HETATM 3533 O O . HOH C 3 . ? 19.088 55.777 9.102 1.00 111.85 ? 856 HOH A O 1 HETATM 3534 O O . HOH C 3 . ? 24.378 123.988 65.100 1.00 81.60 ? 857 HOH A O 1 HETATM 3535 O O . HOH C 3 . ? 50.723 109.879 50.823 1.00 108.90 ? 858 HOH A O 1 HETATM 3536 O O . HOH C 3 . ? 5.032 104.044 23.037 1.00 91.17 ? 859 HOH A O 1 HETATM 3537 O O . HOH C 3 . ? 31.424 81.669 39.616 1.00 175.97 ? 860 HOH A O 1 HETATM 3538 O O . HOH C 3 . ? 26.301 91.484 48.143 1.00 82.30 ? 861 HOH A O 1 HETATM 3539 O O . HOH C 3 . ? 56.175 80.908 34.017 1.00 77.25 ? 862 HOH A O 1 HETATM 3540 O O . HOH C 3 . ? 17.635 94.437 15.546 1.00 78.47 ? 863 HOH A O 1 HETATM 3541 O O . HOH C 3 . ? 17.377 66.285 35.514 1.00 91.76 ? 864 HOH A O 1 HETATM 3542 O O . HOH C 3 . ? 32.862 130.573 55.570 1.00 70.89 ? 865 HOH A O 1 HETATM 3543 O O . HOH C 3 . ? 1.078 92.478 33.156 1.00 97.10 ? 866 HOH A O 1 HETATM 3544 O O . HOH C 3 . ? 33.032 86.822 48.059 1.00 81.80 ? 867 HOH A O 1 HETATM 3545 O O . HOH C 3 . ? 5.373 69.807 25.275 1.00 99.87 ? 868 HOH A O 1 HETATM 3546 O O . HOH C 3 . ? 34.302 113.363 62.895 1.00 79.74 ? 869 HOH A O 1 HETATM 3547 O O . HOH C 3 . ? -4.678 77.040 29.721 1.00 82.61 ? 870 HOH A O 1 HETATM 3548 O O . HOH C 3 . ? 22.729 85.083 42.048 1.00 117.96 ? 871 HOH A O 1 HETATM 3549 O O . HOH C 3 . ? 20.786 76.839 41.842 1.00 81.44 ? 872 HOH A O 1 HETATM 3550 O O . HOH C 3 . ? 53.876 119.932 72.648 1.00 84.46 ? 873 HOH A O 1 HETATM 3551 O O . HOH C 3 . ? 45.881 118.646 67.021 1.00 121.61 ? 874 HOH A O 1 HETATM 3552 O O . HOH C 3 . ? 32.886 79.256 48.595 1.00 89.49 ? 875 HOH A O 1 HETATM 3553 O O . HOH C 3 . ? 26.251 72.215 43.280 1.00 66.84 ? 876 HOH A O 1 HETATM 3554 O O . HOH C 3 . ? 34.593 61.215 19.326 1.00 88.09 ? 877 HOH A O 1 HETATM 3555 O O . HOH C 3 . ? 34.081 71.377 47.547 1.00 113.24 ? 878 HOH A O 1 HETATM 3556 O O . HOH C 3 . ? 16.935 73.712 40.200 1.00 89.86 ? 879 HOH A O 1 HETATM 3557 O O . HOH C 3 . ? 15.699 57.451 26.987 1.00 82.21 ? 880 HOH A O 1 HETATM 3558 O O . HOH C 3 . ? 58.990 79.309 32.052 1.00 81.08 ? 881 HOH A O 1 HETATM 3559 O O . HOH C 3 . ? 46.173 75.424 33.822 1.00 94.13 ? 882 HOH A O 1 HETATM 3560 O O . HOH C 3 . ? 38.874 119.772 50.383 1.00 111.25 ? 883 HOH A O 1 HETATM 3561 O O . HOH C 3 . ? 33.617 65.423 37.239 1.00 82.97 ? 884 HOH A O 1 HETATM 3562 O O . HOH C 3 . ? 34.175 100.065 39.781 1.00 87.58 ? 885 HOH A O 1 HETATM 3563 O O . HOH C 3 . ? 28.009 75.232 13.551 1.00 94.33 ? 886 HOH A O 1 HETATM 3564 O O . HOH C 3 . ? 28.285 93.529 40.644 1.00 89.72 ? 887 HOH A O 1 HETATM 3565 O O . HOH C 3 . ? 3.148 108.913 29.659 1.00 87.13 ? 888 HOH A O 1 HETATM 3566 O O . HOH C 3 . ? 47.667 75.269 41.304 1.00 87.65 ? 889 HOH A O 1 HETATM 3567 O O . HOH C 3 . ? 36.275 74.971 48.188 1.00 113.69 ? 890 HOH A O 1 HETATM 3568 O O . HOH C 3 . ? 14.236 73.370 38.985 1.00 97.46 ? 891 HOH A O 1 HETATM 3569 O O . HOH C 3 . ? -3.106 89.593 29.499 1.00 86.54 ? 892 HOH A O 1 HETATM 3570 O O . HOH C 3 . ? 13.897 47.021 28.879 1.00 67.81 ? 893 HOH A O 1 HETATM 3571 O O . HOH C 3 . ? 6.833 105.042 20.403 1.00 84.57 ? 894 HOH A O 1 HETATM 3572 O O . HOH C 3 . ? 29.604 90.651 56.101 1.00 80.87 ? 895 HOH A O 1 HETATM 3573 O O . HOH C 3 . ? 1.702 104.566 21.857 1.00 81.00 ? 896 HOH A O 1 HETATM 3574 O O . HOH C 3 . ? 30.639 101.351 58.973 1.00 94.58 ? 897 HOH A O 1 HETATM 3575 O O . HOH C 3 . ? 48.861 114.263 50.399 1.00 90.18 ? 898 HOH A O 1 HETATM 3576 O O . HOH C 3 . ? 40.434 76.975 39.637 1.00 71.25 ? 899 HOH A O 1 HETATM 3577 O O . HOH C 3 . ? 33.242 108.080 60.603 1.00 97.35 ? 900 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ILE 1 25 ? ? ? A . n A 1 2 GLU 2 26 ? ? ? A . n A 1 3 ILE 3 27 ? ? ? A . n A 1 4 PRO 4 28 ? ? ? A . n A 1 5 MET 5 29 ? ? ? A . n A 1 6 ASP 6 30 ? ? ? A . n A 1 7 PRO 7 31 ? ? ? A . n A 1 8 SER 8 32 ? ? ? A . n A 1 9 ILE 9 33 ? ? ? A . n A 1 10 GLN 10 34 ? ? ? A . n A 1 11 ASN 11 35 ? ? ? A . n A 1 12 GLU 12 36 ? ? ? A . n A 1 13 LEU 13 37 37 LEU LEU A . n A 1 14 THR 14 38 38 THR THR A . n A 1 15 GLN 15 39 39 GLN GLN A . n A 1 16 PRO 16 40 40 PRO PRO A . n A 1 17 PRO 17 41 41 PRO PRO A . n A 1 18 THR 18 42 42 THR THR A . n A 1 19 ILE 19 43 43 ILE ILE A . n A 1 20 THR 20 44 44 THR THR A . n A 1 21 LYS 21 45 45 LYS LYS A . n A 1 22 GLN 22 46 46 GLN GLN A . n A 1 23 SER 23 47 47 SER SER A . n A 1 24 ALA 24 48 48 ALA ALA A . n A 1 25 LYS 25 49 49 LYS LYS A . n A 1 26 ASP 26 50 50 ASP ASP A . n A 1 27 HIS 27 51 51 HIS HIS A . n A 1 28 ILE 28 52 52 ILE ILE A . n A 1 29 VAL 29 53 53 VAL VAL A . n A 1 30 ASP 30 54 54 ASP ASP A . n A 1 31 PRO 31 55 55 PRO PRO A . n A 1 32 ARG 32 56 56 ARG ARG A . n A 1 33 ASP 33 57 57 ASP ASP A . n A 1 34 ASN 34 58 58 ASN ASN A . n A 1 35 ILE 35 59 59 ILE ILE A . n A 1 36 LEU 36 60 60 LEU LEU A . n A 1 37 ILE 37 61 61 ILE ILE A . n A 1 38 GLU 38 62 62 GLU GLU A . n A 1 39 CYS 39 63 63 CYS CYS A . n A 1 40 GLU 40 64 64 GLU GLU A . n A 1 41 ALA 41 65 65 ALA ALA A . n A 1 42 LYS 42 66 66 LYS LYS A . n A 1 43 GLY 43 67 67 GLY GLY A . n A 1 44 ASN 44 68 68 ASN ASN A . n A 1 45 PRO 45 69 69 PRO PRO A . n A 1 46 ALA 46 70 70 ALA ALA A . n A 1 47 PRO 47 71 71 PRO PRO A . n A 1 48 SER 48 72 72 SER SER A . n A 1 49 PHE 49 73 73 PHE PHE A . n A 1 50 HIS 50 74 74 HIS HIS A . n A 1 51 TRP 51 75 75 TRP TRP A . n A 1 52 THR 52 76 76 THR THR A . n A 1 53 ARG 53 77 77 ARG ARG A . n A 1 54 ASN 54 78 78 ASN ASN A . n A 1 55 SER 55 79 79 SER SER A . n A 1 56 ARG 56 80 80 ARG ARG A . n A 1 57 PHE 57 81 81 PHE PHE A . n A 1 58 PHE 58 82 82 PHE PHE A . n A 1 59 ASN 59 83 83 ASN ASN A . n A 1 60 ILE 60 84 84 ILE ILE A . n A 1 61 ALA 61 85 85 ALA ALA A . n A 1 62 LYS 62 86 86 LYS LYS A . n A 1 63 ASP 63 87 87 ASP ASP A . n A 1 64 PRO 64 88 88 PRO PRO A . n A 1 65 ARG 65 89 89 ARG ARG A . n A 1 66 VAL 66 90 90 VAL VAL A . n A 1 67 SER 67 91 91 SER SER A . n A 1 68 MET 68 92 92 MET MET A . n A 1 69 ARG 69 93 93 ARG ARG A . n A 1 70 ARG 70 94 94 ARG ARG A . n A 1 71 ARG 71 95 95 ARG ARG A . n A 1 72 SER 72 96 96 SER SER A . n A 1 73 GLY 73 97 97 GLY GLY A . n A 1 74 THR 74 98 98 THR THR A . n A 1 75 LEU 75 99 99 LEU LEU A . n A 1 76 VAL 76 100 100 VAL VAL A . n A 1 77 ILE 77 101 101 ILE ILE A . n A 1 78 ASP 78 102 102 ASP ASP A . n A 1 79 PHE 79 103 103 PHE PHE A . n A 1 80 ARG 80 104 104 ARG ARG A . n A 1 81 SER 81 105 105 SER SER A . n A 1 82 GLY 82 106 106 GLY GLY A . n A 1 83 GLY 83 107 107 GLY GLY A . n A 1 84 ARG 84 108 108 ARG ARG A . n A 1 85 PRO 85 109 109 PRO PRO A . n A 1 86 GLU 86 110 110 GLU GLU A . n A 1 87 GLU 87 111 111 GLU GLU A . n A 1 88 TYR 88 112 112 TYR TYR A . n A 1 89 GLU 89 113 113 GLU GLU A . n A 1 90 GLY 90 114 114 GLY GLY A . n A 1 91 GLU 91 115 115 GLU GLU A . n A 1 92 TYR 92 116 116 TYR TYR A . n A 1 93 GLN 93 117 117 GLN GLN A . n A 1 94 CYS 94 118 118 CYS CYS A . n A 1 95 PHE 95 119 119 PHE PHE A . n A 1 96 ALA 96 120 120 ALA ALA A . n A 1 97 ARG 97 121 121 ARG ARG A . n A 1 98 ASN 98 122 122 ASN ASN A . n A 1 99 LYS 99 123 123 LYS LYS A . n A 1 100 PHE 100 124 124 PHE PHE A . n A 1 101 GLY 101 125 125 GLY GLY A . n A 1 102 THR 102 126 126 THR THR A . n A 1 103 ALA 103 127 127 ALA ALA A . n A 1 104 LEU 104 128 128 LEU LEU A . n A 1 105 SER 105 129 129 SER SER A . n A 1 106 ASN 106 130 130 ASN ASN A . n A 1 107 ARG 107 131 131 ARG ARG A . n A 1 108 ILE 108 132 132 ILE ILE A . n A 1 109 ARG 109 133 133 ARG ARG A . n A 1 110 LEU 110 134 134 LEU LEU A . n A 1 111 GLN 111 135 135 GLN GLN A . n A 1 112 VAL 112 136 136 VAL VAL A . n A 1 113 SER 113 137 137 SER SER A . n A 1 114 LYS 114 138 138 LYS LYS A . n A 1 115 SER 115 139 139 SER SER A . n A 1 116 PRO 116 140 140 PRO PRO A . n A 1 117 LEU 117 141 141 LEU LEU A . n A 1 118 TRP 118 142 142 TRP TRP A . n A 1 119 PRO 119 143 143 PRO PRO A . n A 1 120 LYS 120 144 144 LYS LYS A . n A 1 121 GLU 121 145 145 GLU GLU A . n A 1 122 ASN 122 146 146 ASN ASN A . n A 1 123 LEU 123 147 147 LEU LEU A . n A 1 124 ASP 124 148 148 ASP ASP A . n A 1 125 PRO 125 149 149 PRO PRO A . n A 1 126 VAL 126 150 150 VAL VAL A . n A 1 127 VAL 127 151 151 VAL VAL A . n A 1 128 VAL 128 152 152 VAL VAL A . n A 1 129 GLN 129 153 153 GLN GLN A . n A 1 130 GLU 130 154 154 GLU GLU A . n A 1 131 GLY 131 155 155 GLY GLY A . n A 1 132 ALA 132 156 156 ALA ALA A . n A 1 133 PRO 133 157 157 PRO PRO A . n A 1 134 LEU 134 158 158 LEU LEU A . n A 1 135 THR 135 159 159 THR THR A . n A 1 136 LEU 136 160 160 LEU LEU A . n A 1 137 GLN 137 161 161 GLN GLN A . n A 1 138 CYS 138 162 162 CYS CYS A . n A 1 139 ASN 139 163 163 ASN ASN A . n A 1 140 PRO 140 164 164 PRO PRO A . n A 1 141 PRO 141 165 165 PRO PRO A . n A 1 142 PRO 142 166 166 PRO PRO A . n A 1 143 GLY 143 167 167 GLY GLY A . n A 1 144 LEU 144 168 168 LEU LEU A . n A 1 145 PRO 145 169 169 PRO PRO A . n A 1 146 SER 146 170 170 SER SER A . n A 1 147 PRO 147 171 171 PRO PRO A . n A 1 148 VAL 148 172 172 VAL VAL A . n A 1 149 ILE 149 173 173 ILE ILE A . n A 1 150 PHE 150 174 174 PHE PHE A . n A 1 151 TRP 151 175 175 TRP TRP A . n A 1 152 MET 152 176 176 MET MET A . n A 1 153 SER 153 177 177 SER SER A . n A 1 154 SER 154 178 178 SER SER A . n A 1 155 SER 155 179 179 SER SER A . n A 1 156 MET 156 180 180 MET MET A . n A 1 157 GLU 157 181 181 GLU GLU A . n A 1 158 PRO 158 182 182 PRO PRO A . n A 1 159 ILE 159 183 183 ILE ILE A . n A 1 160 THR 160 184 184 THR THR A . n A 1 161 GLN 161 185 185 GLN GLN A . n A 1 162 ASP 162 186 186 ASP ASP A . n A 1 163 LYS 163 187 187 LYS LYS A . n A 1 164 ARG 164 188 188 ARG ARG A . n A 1 165 VAL 165 189 189 VAL VAL A . n A 1 166 SER 166 190 190 SER SER A . n A 1 167 GLN 167 191 191 GLN GLN A . n A 1 168 GLY 168 192 192 GLY GLY A . n A 1 169 HIS 169 193 193 HIS HIS A . n A 1 170 ASN 170 194 194 ASN ASN A . n A 1 171 GLY 171 195 195 GLY GLY A . n A 1 172 ASP 172 196 196 ASP ASP A . n A 1 173 LEU 173 197 197 LEU LEU A . n A 1 174 TYR 174 198 198 TYR TYR A . n A 1 175 PHE 175 199 199 PHE PHE A . n A 1 176 SER 176 200 200 SER SER A . n A 1 177 ASN 177 201 201 ASN ASN A . n A 1 178 VAL 178 202 202 VAL VAL A . n A 1 179 MET 179 203 203 MET MET A . n A 1 180 LEU 180 204 204 LEU LEU A . n A 1 181 GLN 181 205 205 GLN GLN A . n A 1 182 ASP 182 206 206 ASP ASP A . n A 1 183 MET 183 207 207 MET MET A . n A 1 184 GLN 184 208 208 GLN GLN A . n A 1 185 THR 185 209 209 THR THR A . n A 1 186 ASP 186 210 210 ASP ASP A . n A 1 187 TYR 187 211 211 TYR TYR A . n A 1 188 SER 188 212 212 SER SER A . n A 1 189 CYS 189 213 213 CYS CYS A . n A 1 190 ASN 190 214 214 ASN ASN A . n A 1 191 ALA 191 215 215 ALA ALA A . n A 1 192 ARG 192 216 216 ARG ARG A . n A 1 193 PHE 193 217 217 PHE PHE A . n A 1 194 HIS 194 218 218 HIS HIS A . n A 1 195 PHE 195 219 219 PHE PHE A . n A 1 196 THR 196 220 220 THR THR A . n A 1 197 HIS 197 221 221 HIS HIS A . n A 1 198 THR 198 222 222 THR THR A . n A 1 199 ILE 199 223 223 ILE ILE A . n A 1 200 GLN 200 224 224 GLN GLN A . n A 1 201 GLN 201 225 225 GLN GLN A . n A 1 202 LYS 202 226 226 LYS LYS A . n A 1 203 ASN 203 227 227 ASN ASN A . n A 1 204 PRO 204 228 228 PRO PRO A . n A 1 205 PHE 205 229 229 PHE PHE A . n A 1 206 THR 206 230 230 THR THR A . n A 1 207 LEU 207 231 231 LEU LEU A . n A 1 208 LYS 208 232 232 LYS LYS A . n A 1 209 VAL 209 233 233 VAL VAL A . n A 1 210 LEU 210 234 234 LEU LEU A . n A 1 211 THR 211 235 235 THR THR A . n A 1 212 THR 212 236 236 THR THR A . n A 1 213 ARG 213 237 237 ARG ARG A . n A 1 214 GLY 214 238 238 GLY GLY A . n A 1 215 VAL 215 239 239 VAL VAL A . n A 1 216 ALA 216 240 240 ALA ALA A . n A 1 217 GLU 217 241 241 GLU GLU A . n A 1 218 ARG 218 242 242 ARG ARG A . n A 1 219 THR 219 243 243 THR THR A . n A 1 220 PRO 220 244 244 PRO PRO A . n A 1 221 SER 221 245 245 SER SER A . n A 1 222 PHE 222 246 246 PHE PHE A . n A 1 223 MET 223 247 247 MET MET A . n A 1 224 TYR 224 248 248 TYR TYR A . n A 1 225 PRO 225 249 249 PRO PRO A . n A 1 226 GLN 226 250 250 GLN GLN A . n A 1 227 GLY 227 251 251 GLY GLY A . n A 1 228 THR 228 252 252 THR THR A . n A 1 229 ALA 229 253 253 ALA ALA A . n A 1 230 SER 230 254 254 SER SER A . n A 1 231 SER 231 255 255 SER SER A . n A 1 232 GLN 232 256 256 GLN GLN A . n A 1 233 MET 233 257 257 MET MET A . n A 1 234 VAL 234 258 258 VAL VAL A . n A 1 235 LEU 235 259 259 LEU LEU A . n A 1 236 ARG 236 260 260 ARG ARG A . n A 1 237 GLY 237 261 261 GLY GLY A . n A 1 238 MET 238 262 262 MET MET A . n A 1 239 ASP 239 263 263 ASP ASP A . n A 1 240 LEU 240 264 264 LEU LEU A . n A 1 241 LEU 241 265 265 LEU LEU A . n A 1 242 LEU 242 266 266 LEU LEU A . n A 1 243 GLU 243 267 267 GLU GLU A . n A 1 244 CYS 244 268 268 CYS CYS A . n A 1 245 ILE 245 269 269 ILE ILE A . n A 1 246 ALA 246 270 270 ALA ALA A . n A 1 247 SER 247 271 271 SER SER A . n A 1 248 GLY 248 272 272 GLY GLY A . n A 1 249 VAL 249 273 273 VAL VAL A . n A 1 250 PRO 250 274 274 PRO PRO A . n A 1 251 THR 251 275 275 THR THR A . n A 1 252 PRO 252 276 276 PRO PRO A . n A 1 253 ASP 253 277 277 ASP ASP A . n A 1 254 ILE 254 278 278 ILE ILE A . n A 1 255 ALA 255 279 279 ALA ALA A . n A 1 256 TRP 256 280 280 TRP TRP A . n A 1 257 TYR 257 281 281 TYR TYR A . n A 1 258 LYS 258 282 282 LYS LYS A . n A 1 259 LYS 259 283 283 LYS LYS A . n A 1 260 GLY 260 284 284 GLY GLY A . n A 1 261 GLY 261 285 285 GLY GLY A . n A 1 262 ASP 262 286 286 ASP ASP A . n A 1 263 LEU 263 287 287 LEU LEU A . n A 1 264 PRO 264 288 288 PRO PRO A . n A 1 265 SER 265 289 289 SER SER A . n A 1 266 ASP 266 290 290 ASP ASP A . n A 1 267 LYS 267 291 291 LYS LYS A . n A 1 268 ALA 268 292 292 ALA ALA A . n A 1 269 LYS 269 293 293 LYS LYS A . n A 1 270 PHE 270 294 294 PHE PHE A . n A 1 271 GLU 271 295 295 GLU GLU A . n A 1 272 ASN 272 296 296 ASN ASN A . n A 1 273 PHE 273 297 297 PHE PHE A . n A 1 274 ASN 274 298 298 ASN ASN A . n A 1 275 LYS 275 299 299 LYS LYS A . n A 1 276 ALA 276 300 300 ALA ALA A . n A 1 277 LEU 277 301 301 LEU LEU A . n A 1 278 ARG 278 302 302 ARG ARG A . n A 1 279 ILE 279 303 303 ILE ILE A . n A 1 280 THR 280 304 304 THR THR A . n A 1 281 ASN 281 305 305 ASN ASN A . n A 1 282 VAL 282 306 306 VAL VAL A . n A 1 283 SER 283 307 307 SER SER A . n A 1 284 GLU 284 308 308 GLU GLU A . n A 1 285 GLU 285 309 309 GLU GLU A . n A 1 286 ASP 286 310 310 ASP ASP A . n A 1 287 SER 287 311 311 SER SER A . n A 1 288 GLY 288 312 312 GLY GLY A . n A 1 289 GLU 289 313 313 GLU GLU A . n A 1 290 TYR 290 314 314 TYR TYR A . n A 1 291 PHE 291 315 315 PHE PHE A . n A 1 292 CYS 292 316 316 CYS CYS A . n A 1 293 LEU 293 317 317 LEU LEU A . n A 1 294 ALA 294 318 318 ALA ALA A . n A 1 295 SER 295 319 319 SER SER A . n A 1 296 ASN 296 320 320 ASN ASN A . n A 1 297 LYS 297 321 321 LYS LYS A . n A 1 298 MET 298 322 322 MET MET A . n A 1 299 GLY 299 323 323 GLY GLY A . n A 1 300 SER 300 324 324 SER SER A . n A 1 301 ILE 301 325 325 ILE ILE A . n A 1 302 ARG 302 326 326 ARG ARG A . n A 1 303 HIS 303 327 327 HIS HIS A . n A 1 304 THR 304 328 328 THR THR A . n A 1 305 ILE 305 329 329 ILE ILE A . n A 1 306 SER 306 330 330 SER SER A . n A 1 307 VAL 307 331 331 VAL VAL A . n A 1 308 ARG 308 332 332 ARG ARG A . n A 1 309 VAL 309 333 333 VAL VAL A . n A 1 310 LYS 310 334 334 LYS LYS A . n A 1 311 ALA 311 335 335 ALA ALA A . n A 1 312 ALA 312 336 336 ALA ALA A . n A 1 313 PRO 313 337 337 PRO PRO A . n A 1 314 TYR 314 338 338 TYR TYR A . n A 1 315 TRP 315 339 339 TRP TRP A . n A 1 316 LEU 316 340 340 LEU LEU A . n A 1 317 ASP 317 341 341 ASP ASP A . n A 1 318 GLU 318 342 342 GLU GLU A . n A 1 319 PRO 319 343 343 PRO PRO A . n A 1 320 LYS 320 344 344 LYS LYS A . n A 1 321 ASN 321 345 345 ASN ASN A . n A 1 322 LEU 322 346 346 LEU LEU A . n A 1 323 ILE 323 347 347 ILE ILE A . n A 1 324 LEU 324 348 348 LEU LEU A . n A 1 325 ALA 325 349 349 ALA ALA A . n A 1 326 PRO 326 350 350 PRO PRO A . n A 1 327 GLY 327 351 351 GLY GLY A . n A 1 328 GLU 328 352 352 GLU GLU A . n A 1 329 ASP 329 353 353 ASP ASP A . n A 1 330 GLY 330 354 354 GLY GLY A . n A 1 331 ARG 331 355 355 ARG ARG A . n A 1 332 LEU 332 356 356 LEU LEU A . n A 1 333 VAL 333 357 357 VAL VAL A . n A 1 334 CYS 334 358 358 CYS CYS A . n A 1 335 ARG 335 359 359 ARG ARG A . n A 1 336 ALA 336 360 360 ALA ALA A . n A 1 337 ASN 337 361 361 ASN ASN A . n A 1 338 GLY 338 362 362 GLY GLY A . n A 1 339 ASN 339 363 363 ASN ASN A . n A 1 340 PRO 340 364 364 PRO PRO A . n A 1 341 LYS 341 365 365 LYS LYS A . n A 1 342 PRO 342 366 366 PRO PRO A . n A 1 343 THR 343 367 367 THR THR A . n A 1 344 VAL 344 368 368 VAL VAL A . n A 1 345 GLN 345 369 369 GLN GLN A . n A 1 346 TRP 346 370 370 TRP TRP A . n A 1 347 MET 347 371 371 MET MET A . n A 1 348 VAL 348 372 372 VAL VAL A . n A 1 349 ASN 349 373 373 ASN ASN A . n A 1 350 GLY 350 374 374 GLY GLY A . n A 1 351 GLU 351 375 375 GLU GLU A . n A 1 352 PRO 352 376 376 PRO PRO A . n A 1 353 LEU 353 377 377 LEU LEU A . n A 1 354 GLN 354 378 378 GLN GLN A . n A 1 355 SER 355 379 379 SER SER A . n A 1 356 ALA 356 380 380 ALA ALA A . n A 1 357 PRO 357 381 381 PRO PRO A . n A 1 358 PRO 358 382 382 PRO PRO A . n A 1 359 ASN 359 383 383 ASN ASN A . n A 1 360 PRO 360 384 384 PRO PRO A . n A 1 361 ASN 361 385 385 ASN ASN A . n A 1 362 ARG 362 386 386 ARG ARG A . n A 1 363 GLU 363 387 387 GLU GLU A . n A 1 364 VAL 364 388 388 VAL VAL A . n A 1 365 ALA 365 389 389 ALA ALA A . n A 1 366 GLY 366 390 390 GLY GLY A . n A 1 367 ASP 367 391 391 ASP ASP A . n A 1 368 THR 368 392 392 THR THR A . n A 1 369 ILE 369 393 393 ILE ILE A . n A 1 370 ILE 370 394 394 ILE ILE A . n A 1 371 PHE 371 395 395 PHE PHE A . n A 1 372 ARG 372 396 396 ARG ARG A . n A 1 373 ASP 373 397 397 ASP ASP A . n A 1 374 THR 374 398 398 THR THR A . n A 1 375 GLN 375 399 399 GLN GLN A . n A 1 376 ILE 376 400 400 ILE ILE A . n A 1 377 SER 377 401 401 SER SER A . n A 1 378 SER 378 402 402 SER SER A . n A 1 379 ARG 379 403 403 ARG ARG A . n A 1 380 ALA 380 404 404 ALA ALA A . n A 1 381 VAL 381 405 405 VAL VAL A . n A 1 382 TYR 382 406 406 TYR TYR A . n A 1 383 GLN 383 407 407 GLN GLN A . n A 1 384 CYS 384 408 408 CYS CYS A . n A 1 385 ASN 385 409 409 ASN ASN A . n A 1 386 THR 386 410 410 THR THR A . n A 1 387 SER 387 411 411 SER SER A . n A 1 388 ASN 388 412 412 ASN ASN A . n A 1 389 GLU 389 413 413 GLU GLU A . n A 1 390 HIS 390 414 414 HIS HIS A . n A 1 391 GLY 391 415 415 GLY GLY A . n A 1 392 TYR 392 416 416 TYR TYR A . n A 1 393 LEU 393 417 417 LEU LEU A . n A 1 394 LEU 394 418 418 LEU LEU A . n A 1 395 ALA 395 419 419 ALA ALA A . n A 1 396 ASN 396 420 420 ASN ASN A . n A 1 397 ALA 397 421 421 ALA ALA A . n A 1 398 PHE 398 422 422 PHE PHE A . n A 1 399 VAL 399 423 423 VAL VAL A . n A 1 400 SER 400 424 424 SER SER A . n A 1 401 VAL 401 425 425 VAL VAL A . n A 1 402 LEU 402 426 426 LEU LEU A . n A 1 403 ASP 403 427 ? ? ? A . n A 1 404 VAL 404 428 ? ? ? A . n # _pdbx_struct_mod_residue.id 1 _pdbx_struct_mod_residue.label_asym_id A _pdbx_struct_mod_residue.label_comp_id ASN _pdbx_struct_mod_residue.label_seq_id 385 _pdbx_struct_mod_residue.auth_asym_id A _pdbx_struct_mod_residue.auth_comp_id ASN _pdbx_struct_mod_residue.auth_seq_id 409 _pdbx_struct_mod_residue.PDB_ins_code ? _pdbx_struct_mod_residue.parent_comp_id ASN _pdbx_struct_mod_residue.details 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_defined_assembly ? dimeric 2 2 software_defined_assembly PISA monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1,2 A,B,C 2 1 A,B,C # loop_ _pdbx_struct_oper_list.id _pdbx_struct_oper_list.type _pdbx_struct_oper_list.name _pdbx_struct_oper_list.symmetry_operation _pdbx_struct_oper_list.matrix[1][1] _pdbx_struct_oper_list.matrix[1][2] _pdbx_struct_oper_list.matrix[1][3] _pdbx_struct_oper_list.vector[1] _pdbx_struct_oper_list.matrix[2][1] _pdbx_struct_oper_list.matrix[2][2] _pdbx_struct_oper_list.matrix[2][3] _pdbx_struct_oper_list.vector[2] _pdbx_struct_oper_list.matrix[3][1] _pdbx_struct_oper_list.matrix[3][2] _pdbx_struct_oper_list.matrix[3][3] _pdbx_struct_oper_list.vector[3] 1 'identity operation' 1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 2 'crystal symmetry operation' 12_565 x,x-y+1,-z+5/6 0.5000000000 0.8660254038 0.0000000000 -85.7125000000 0.8660254038 -0.5000000000 0.0000000000 148.4584048437 0.0000000000 0.0000000000 -1.0000000000 73.1600000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2010-11-03 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal HKL-2000 'data collection' . ? 1 SOLVE phasing . ? 2 CNS refinement 1.1 ? 3 HKL-2000 'data reduction' . ? 4 HKL-2000 'data scaling' . ? 5 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 O A HOH 456 ? ? O A HOH 762 ? ? 2.00 2 1 O A HOH 526 ? ? O A HOH 778 ? ? 2.02 3 1 N A ASP 397 ? ? O A HOH 773 ? ? 2.03 4 1 O A HOH 483 ? ? O A HOH 524 ? ? 2.06 5 1 OD1 A ASN 409 ? ? O A HOH 812 ? ? 2.07 6 1 ND2 A ASN 409 ? ? O5 A NAG 1 ? ? 2.08 7 1 O A ARG 133 ? ? O A HOH 431 ? ? 2.08 8 1 O A LEU 417 ? ? O A HOH 812 ? ? 2.08 9 1 N A THR 410 ? ? O A HOH 812 ? ? 2.10 10 1 O A HOH 570 ? ? O A HOH 764 ? ? 2.10 11 1 O A HOH 3 ? ? O A HOH 765 ? ? 2.10 12 1 O A HOH 7 ? ? O A HOH 780 ? ? 2.11 13 1 O A HOH 565 ? ? O A HOH 890 ? ? 2.11 14 1 O A HOH 434 ? ? O A HOH 659 ? ? 2.12 15 1 O A HOH 18 ? ? O A HOH 736 ? ? 2.12 16 1 O A HOH 496 ? ? O A HOH 852 ? ? 2.13 17 1 O A HOH 16 ? ? O A HOH 533 ? ? 2.14 18 1 O A LYS 123 ? ? O A HOH 485 ? ? 2.14 19 1 O A HOH 434 ? ? O A HOH 598 ? ? 2.15 20 1 O A HOH 532 ? ? O A HOH 852 ? ? 2.16 21 1 NE2 A GLN 185 ? ? O A HOH 495 ? ? 2.19 22 1 O A HOH 22 ? ? O A HOH 802 ? ? 2.19 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 N A ALA 85 ? ? CA A ALA 85 ? ? C A ALA 85 ? ? 130.03 111.00 19.03 2.70 N 2 1 N A LYS 86 ? ? CA A LYS 86 ? ? CB A LYS 86 ? ? 98.14 110.60 -12.46 1.80 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 THR A 38 ? ? -69.63 75.48 2 1 PRO A 40 ? ? -58.60 172.02 3 1 PRO A 55 ? ? -58.50 3.50 4 1 ARG A 56 ? ? -67.50 -109.23 5 1 CYS A 63 ? ? -167.62 116.45 6 1 SER A 79 ? ? 69.79 -0.23 7 1 ALA A 85 ? ? -39.14 -27.62 8 1 ARG A 95 ? ? 53.04 16.66 9 1 ARG A 104 ? ? -61.56 0.76 10 1 SER A 137 ? ? -68.25 94.72 11 1 ASN A 163 ? ? 52.87 74.79 12 1 PRO A 166 ? ? -45.25 -95.68 13 1 ASP A 206 ? ? -66.61 3.58 14 1 ARG A 237 ? ? 47.97 70.65 15 1 ALA A 240 ? ? -12.15 105.40 16 1 TYR A 248 ? ? -74.41 -71.07 17 1 ASN A 298 ? ? 70.75 -7.39 18 1 THR A 304 ? ? -72.32 -83.95 19 1 ASN A 320 ? ? -78.75 -155.68 20 1 SER A 324 ? ? -164.55 100.88 21 1 SER A 379 ? ? -108.33 40.43 22 1 SER A 401 ? ? -71.47 -154.49 23 1 GLU A 413 ? ? -37.68 -36.63 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ILE 25 ? A ILE 1 2 1 Y 1 A GLU 26 ? A GLU 2 3 1 Y 1 A ILE 27 ? A ILE 3 4 1 Y 1 A PRO 28 ? A PRO 4 5 1 Y 1 A MET 29 ? A MET 5 6 1 Y 1 A ASP 30 ? A ASP 6 7 1 Y 1 A PRO 31 ? A PRO 7 8 1 Y 1 A SER 32 ? A SER 8 9 1 Y 1 A ILE 33 ? A ILE 9 10 1 Y 1 A GLN 34 ? A GLN 10 11 1 Y 1 A ASN 35 ? A ASN 11 12 1 Y 1 A GLU 36 ? A GLU 12 13 1 Y 1 A ASP 427 ? A ASP 403 14 1 Y 1 A VAL 428 ? A VAL 404 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 water HOH # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 1 1 NAG NAG A . C 3 HOH 1 2 2 HOH WAT A . C 3 HOH 2 3 3 HOH WAT A . C 3 HOH 3 4 4 HOH WAT A . C 3 HOH 4 5 5 HOH WAT A . C 3 HOH 5 6 6 HOH WAT A . C 3 HOH 6 7 7 HOH WAT A . C 3 HOH 7 8 8 HOH WAT A . C 3 HOH 8 9 9 HOH WAT A . C 3 HOH 9 10 10 HOH WAT A . C 3 HOH 10 11 11 HOH WAT A . C 3 HOH 11 12 12 HOH WAT A . C 3 HOH 12 13 13 HOH WAT A . C 3 HOH 13 14 14 HOH WAT A . C 3 HOH 14 15 15 HOH WAT A . C 3 HOH 15 16 16 HOH WAT A . C 3 HOH 16 17 17 HOH WAT A . C 3 HOH 17 18 18 HOH WAT A . C 3 HOH 18 19 19 HOH WAT A . C 3 HOH 19 20 20 HOH WAT A . C 3 HOH 20 21 21 HOH WAT A . C 3 HOH 21 22 22 HOH WAT A . C 3 HOH 22 23 23 HOH WAT A . C 3 HOH 23 24 24 HOH WAT A . C 3 HOH 24 429 429 HOH WAT A . C 3 HOH 25 430 430 HOH WAT A . C 3 HOH 26 431 431 HOH WAT A . C 3 HOH 27 432 432 HOH WAT A . C 3 HOH 28 433 433 HOH WAT A . C 3 HOH 29 434 434 HOH WAT A . C 3 HOH 30 435 435 HOH WAT A . C 3 HOH 31 436 436 HOH WAT A . C 3 HOH 32 437 437 HOH WAT A . C 3 HOH 33 438 438 HOH WAT A . C 3 HOH 34 439 439 HOH WAT A . C 3 HOH 35 440 440 HOH WAT A . C 3 HOH 36 441 441 HOH WAT A . C 3 HOH 37 442 442 HOH WAT A . C 3 HOH 38 443 443 HOH WAT A . C 3 HOH 39 444 444 HOH WAT A . C 3 HOH 40 445 445 HOH WAT A . C 3 HOH 41 446 446 HOH WAT A . C 3 HOH 42 447 447 HOH WAT A . C 3 HOH 43 448 448 HOH WAT A . C 3 HOH 44 449 449 HOH WAT A . C 3 HOH 45 450 450 HOH WAT A . C 3 HOH 46 451 451 HOH WAT A . C 3 HOH 47 452 452 HOH WAT A . C 3 HOH 48 453 453 HOH WAT A . C 3 HOH 49 454 454 HOH WAT A . C 3 HOH 50 455 455 HOH WAT A . C 3 HOH 51 456 456 HOH WAT A . C 3 HOH 52 457 457 HOH WAT A . C 3 HOH 53 458 458 HOH WAT A . C 3 HOH 54 459 459 HOH WAT A . C 3 HOH 55 460 460 HOH WAT A . C 3 HOH 56 461 461 HOH WAT A . C 3 HOH 57 462 462 HOH WAT A . C 3 HOH 58 463 463 HOH WAT A . C 3 HOH 59 464 464 HOH WAT A . C 3 HOH 60 465 465 HOH WAT A . C 3 HOH 61 466 466 HOH WAT A . C 3 HOH 62 467 467 HOH WAT A . C 3 HOH 63 468 468 HOH WAT A . C 3 HOH 64 469 469 HOH WAT A . C 3 HOH 65 470 470 HOH WAT A . C 3 HOH 66 471 471 HOH WAT A . C 3 HOH 67 472 472 HOH WAT A . C 3 HOH 68 473 473 HOH WAT A . C 3 HOH 69 474 474 HOH WAT A . C 3 HOH 70 475 475 HOH WAT A . C 3 HOH 71 476 476 HOH WAT A . C 3 HOH 72 477 477 HOH WAT A . C 3 HOH 73 478 478 HOH WAT A . C 3 HOH 74 479 479 HOH WAT A . C 3 HOH 75 480 480 HOH WAT A . C 3 HOH 76 481 481 HOH WAT A . C 3 HOH 77 482 482 HOH WAT A . C 3 HOH 78 483 483 HOH WAT A . C 3 HOH 79 484 484 HOH WAT A . C 3 HOH 80 485 485 HOH WAT A . C 3 HOH 81 486 486 HOH WAT A . C 3 HOH 82 487 487 HOH WAT A . C 3 HOH 83 488 488 HOH WAT A . C 3 HOH 84 489 489 HOH WAT A . C 3 HOH 85 490 490 HOH WAT A . C 3 HOH 86 491 491 HOH WAT A . C 3 HOH 87 492 492 HOH WAT A . C 3 HOH 88 493 493 HOH WAT A . C 3 HOH 89 494 494 HOH WAT A . C 3 HOH 90 495 495 HOH WAT A . C 3 HOH 91 496 1 HOH WAT A . C 3 HOH 92 497 25 HOH WAT A . C 3 HOH 93 498 26 HOH WAT A . C 3 HOH 94 499 27 HOH WAT A . C 3 HOH 95 500 28 HOH WAT A . C 3 HOH 96 501 29 HOH WAT A . C 3 HOH 97 502 30 HOH WAT A . C 3 HOH 98 503 31 HOH WAT A . C 3 HOH 99 504 32 HOH WAT A . C 3 HOH 100 505 33 HOH WAT A . C 3 HOH 101 506 34 HOH WAT A . C 3 HOH 102 507 35 HOH WAT A . C 3 HOH 103 508 36 HOH WAT A . C 3 HOH 104 509 37 HOH WAT A . C 3 HOH 105 510 38 HOH WAT A . C 3 HOH 106 511 39 HOH WAT A . C 3 HOH 107 512 40 HOH WAT A . C 3 HOH 108 513 41 HOH WAT A . C 3 HOH 109 514 42 HOH WAT A . C 3 HOH 110 515 43 HOH WAT A . C 3 HOH 111 516 44 HOH WAT A . C 3 HOH 112 517 45 HOH WAT A . C 3 HOH 113 518 46 HOH WAT A . C 3 HOH 114 519 47 HOH WAT A . C 3 HOH 115 520 48 HOH WAT A . C 3 HOH 116 521 49 HOH WAT A . C 3 HOH 117 522 50 HOH WAT A . C 3 HOH 118 523 51 HOH WAT A . C 3 HOH 119 524 52 HOH WAT A . C 3 HOH 120 525 53 HOH WAT A . C 3 HOH 121 526 54 HOH WAT A . C 3 HOH 122 527 55 HOH WAT A . C 3 HOH 123 528 56 HOH WAT A . C 3 HOH 124 529 57 HOH WAT A . C 3 HOH 125 530 58 HOH WAT A . C 3 HOH 126 531 59 HOH WAT A . C 3 HOH 127 532 60 HOH WAT A . C 3 HOH 128 533 61 HOH WAT A . C 3 HOH 129 534 62 HOH WAT A . C 3 HOH 130 535 63 HOH WAT A . C 3 HOH 131 536 64 HOH WAT A . C 3 HOH 132 537 65 HOH WAT A . C 3 HOH 133 538 66 HOH WAT A . C 3 HOH 134 539 67 HOH WAT A . C 3 HOH 135 540 68 HOH WAT A . C 3 HOH 136 541 69 HOH WAT A . C 3 HOH 137 542 70 HOH WAT A . C 3 HOH 138 543 71 HOH WAT A . C 3 HOH 139 544 72 HOH WAT A . C 3 HOH 140 545 73 HOH WAT A . C 3 HOH 141 546 74 HOH WAT A . C 3 HOH 142 547 75 HOH WAT A . C 3 HOH 143 548 76 HOH WAT A . C 3 HOH 144 549 77 HOH WAT A . C 3 HOH 145 550 78 HOH WAT A . C 3 HOH 146 551 79 HOH WAT A . C 3 HOH 147 552 80 HOH WAT A . C 3 HOH 148 553 81 HOH WAT A . C 3 HOH 149 554 82 HOH WAT A . C 3 HOH 150 555 83 HOH WAT A . C 3 HOH 151 556 84 HOH WAT A . C 3 HOH 152 557 85 HOH WAT A . C 3 HOH 153 558 86 HOH WAT A . C 3 HOH 154 559 87 HOH WAT A . C 3 HOH 155 560 88 HOH WAT A . C 3 HOH 156 561 89 HOH WAT A . C 3 HOH 157 562 90 HOH WAT A . C 3 HOH 158 563 91 HOH WAT A . C 3 HOH 159 564 92 HOH WAT A . C 3 HOH 160 565 93 HOH WAT A . C 3 HOH 161 566 94 HOH WAT A . C 3 HOH 162 567 95 HOH WAT A . C 3 HOH 163 568 96 HOH WAT A . C 3 HOH 164 569 97 HOH WAT A . C 3 HOH 165 570 98 HOH WAT A . C 3 HOH 166 571 99 HOH WAT A . C 3 HOH 167 572 100 HOH WAT A . C 3 HOH 168 573 101 HOH WAT A . C 3 HOH 169 574 102 HOH WAT A . C 3 HOH 170 575 103 HOH WAT A . C 3 HOH 171 576 104 HOH WAT A . C 3 HOH 172 577 105 HOH WAT A . C 3 HOH 173 578 106 HOH WAT A . C 3 HOH 174 579 107 HOH WAT A . C 3 HOH 175 580 108 HOH WAT A . C 3 HOH 176 581 109 HOH WAT A . C 3 HOH 177 582 110 HOH WAT A . C 3 HOH 178 583 111 HOH WAT A . C 3 HOH 179 584 112 HOH WAT A . C 3 HOH 180 585 113 HOH WAT A . C 3 HOH 181 586 114 HOH WAT A . C 3 HOH 182 587 115 HOH WAT A . C 3 HOH 183 588 116 HOH WAT A . C 3 HOH 184 589 117 HOH WAT A . C 3 HOH 185 590 118 HOH WAT A . C 3 HOH 186 591 119 HOH WAT A . C 3 HOH 187 592 120 HOH WAT A . C 3 HOH 188 593 121 HOH WAT A . C 3 HOH 189 594 122 HOH WAT A . C 3 HOH 190 595 123 HOH WAT A . C 3 HOH 191 596 124 HOH WAT A . C 3 HOH 192 597 125 HOH WAT A . C 3 HOH 193 598 126 HOH WAT A . C 3 HOH 194 599 127 HOH WAT A . C 3 HOH 195 600 128 HOH WAT A . C 3 HOH 196 601 129 HOH WAT A . C 3 HOH 197 602 130 HOH WAT A . C 3 HOH 198 603 131 HOH WAT A . C 3 HOH 199 604 132 HOH WAT A . C 3 HOH 200 605 133 HOH WAT A . C 3 HOH 201 606 134 HOH WAT A . C 3 HOH 202 607 135 HOH WAT A . C 3 HOH 203 608 136 HOH WAT A . C 3 HOH 204 609 137 HOH WAT A . C 3 HOH 205 610 138 HOH WAT A . C 3 HOH 206 611 139 HOH WAT A . C 3 HOH 207 612 140 HOH WAT A . C 3 HOH 208 613 141 HOH WAT A . C 3 HOH 209 614 142 HOH WAT A . C 3 HOH 210 615 143 HOH WAT A . C 3 HOH 211 616 144 HOH WAT A . C 3 HOH 212 617 145 HOH WAT A . C 3 HOH 213 618 146 HOH WAT A . C 3 HOH 214 619 147 HOH WAT A . C 3 HOH 215 620 148 HOH WAT A . C 3 HOH 216 621 149 HOH WAT A . C 3 HOH 217 622 150 HOH WAT A . C 3 HOH 218 623 151 HOH WAT A . C 3 HOH 219 624 152 HOH WAT A . C 3 HOH 220 625 153 HOH WAT A . C 3 HOH 221 626 154 HOH WAT A . C 3 HOH 222 627 155 HOH WAT A . C 3 HOH 223 628 156 HOH WAT A . C 3 HOH 224 629 157 HOH WAT A . C 3 HOH 225 630 158 HOH WAT A . C 3 HOH 226 631 159 HOH WAT A . C 3 HOH 227 632 160 HOH WAT A . C 3 HOH 228 633 161 HOH WAT A . C 3 HOH 229 634 162 HOH WAT A . C 3 HOH 230 635 163 HOH WAT A . C 3 HOH 231 636 164 HOH WAT A . C 3 HOH 232 637 165 HOH WAT A . C 3 HOH 233 638 166 HOH WAT A . C 3 HOH 234 639 167 HOH WAT A . C 3 HOH 235 640 168 HOH WAT A . C 3 HOH 236 641 169 HOH WAT A . C 3 HOH 237 642 170 HOH WAT A . C 3 HOH 238 643 171 HOH WAT A . C 3 HOH 239 644 172 HOH WAT A . C 3 HOH 240 645 173 HOH WAT A . C 3 HOH 241 646 174 HOH WAT A . C 3 HOH 242 647 175 HOH WAT A . C 3 HOH 243 648 176 HOH WAT A . C 3 HOH 244 649 177 HOH WAT A . C 3 HOH 245 650 178 HOH WAT A . C 3 HOH 246 651 179 HOH WAT A . C 3 HOH 247 652 180 HOH WAT A . C 3 HOH 248 653 181 HOH WAT A . C 3 HOH 249 654 182 HOH WAT A . C 3 HOH 250 655 183 HOH WAT A . C 3 HOH 251 656 184 HOH WAT A . C 3 HOH 252 657 185 HOH WAT A . C 3 HOH 253 658 186 HOH WAT A . C 3 HOH 254 659 187 HOH WAT A . C 3 HOH 255 660 188 HOH WAT A . C 3 HOH 256 661 189 HOH WAT A . C 3 HOH 257 662 190 HOH WAT A . C 3 HOH 258 663 191 HOH WAT A . C 3 HOH 259 664 192 HOH WAT A . C 3 HOH 260 665 193 HOH WAT A . C 3 HOH 261 666 194 HOH WAT A . C 3 HOH 262 667 195 HOH WAT A . C 3 HOH 263 668 196 HOH WAT A . C 3 HOH 264 669 197 HOH WAT A . C 3 HOH 265 670 198 HOH WAT A . C 3 HOH 266 671 199 HOH WAT A . C 3 HOH 267 672 200 HOH WAT A . C 3 HOH 268 673 201 HOH WAT A . C 3 HOH 269 674 202 HOH WAT A . C 3 HOH 270 675 203 HOH WAT A . C 3 HOH 271 676 204 HOH WAT A . C 3 HOH 272 677 205 HOH WAT A . C 3 HOH 273 678 206 HOH WAT A . C 3 HOH 274 679 207 HOH WAT A . C 3 HOH 275 680 208 HOH WAT A . C 3 HOH 276 681 209 HOH WAT A . C 3 HOH 277 682 210 HOH WAT A . C 3 HOH 278 683 211 HOH WAT A . C 3 HOH 279 684 212 HOH WAT A . C 3 HOH 280 685 213 HOH WAT A . C 3 HOH 281 686 214 HOH WAT A . C 3 HOH 282 687 215 HOH WAT A . C 3 HOH 283 688 216 HOH WAT A . C 3 HOH 284 689 217 HOH WAT A . C 3 HOH 285 690 218 HOH WAT A . C 3 HOH 286 691 219 HOH WAT A . C 3 HOH 287 692 220 HOH WAT A . C 3 HOH 288 693 221 HOH WAT A . C 3 HOH 289 694 222 HOH WAT A . C 3 HOH 290 695 223 HOH WAT A . C 3 HOH 291 696 224 HOH WAT A . C 3 HOH 292 697 225 HOH WAT A . C 3 HOH 293 698 226 HOH WAT A . C 3 HOH 294 699 227 HOH WAT A . C 3 HOH 295 700 228 HOH WAT A . C 3 HOH 296 701 229 HOH WAT A . C 3 HOH 297 702 230 HOH WAT A . C 3 HOH 298 703 231 HOH WAT A . C 3 HOH 299 704 232 HOH WAT A . C 3 HOH 300 705 233 HOH WAT A . C 3 HOH 301 706 234 HOH WAT A . C 3 HOH 302 707 235 HOH WAT A . C 3 HOH 303 708 236 HOH WAT A . C 3 HOH 304 709 237 HOH WAT A . C 3 HOH 305 710 238 HOH WAT A . C 3 HOH 306 711 239 HOH WAT A . C 3 HOH 307 712 240 HOH WAT A . C 3 HOH 308 713 241 HOH WAT A . C 3 HOH 309 714 242 HOH WAT A . C 3 HOH 310 715 243 HOH WAT A . C 3 HOH 311 716 244 HOH WAT A . C 3 HOH 312 717 245 HOH WAT A . C 3 HOH 313 718 246 HOH WAT A . C 3 HOH 314 719 247 HOH WAT A . C 3 HOH 315 720 248 HOH WAT A . C 3 HOH 316 721 249 HOH WAT A . C 3 HOH 317 722 250 HOH WAT A . C 3 HOH 318 723 251 HOH WAT A . C 3 HOH 319 724 252 HOH WAT A . C 3 HOH 320 725 253 HOH WAT A . C 3 HOH 321 726 254 HOH WAT A . C 3 HOH 322 727 255 HOH WAT A . C 3 HOH 323 728 256 HOH WAT A . C 3 HOH 324 729 257 HOH WAT A . C 3 HOH 325 730 258 HOH WAT A . C 3 HOH 326 731 259 HOH WAT A . C 3 HOH 327 732 260 HOH WAT A . C 3 HOH 328 733 261 HOH WAT A . C 3 HOH 329 734 262 HOH WAT A . C 3 HOH 330 735 263 HOH WAT A . C 3 HOH 331 736 264 HOH WAT A . C 3 HOH 332 737 265 HOH WAT A . C 3 HOH 333 738 266 HOH WAT A . C 3 HOH 334 739 267 HOH WAT A . C 3 HOH 335 740 268 HOH WAT A . C 3 HOH 336 741 269 HOH WAT A . C 3 HOH 337 742 270 HOH WAT A . C 3 HOH 338 743 271 HOH WAT A . C 3 HOH 339 744 272 HOH WAT A . C 3 HOH 340 745 273 HOH WAT A . C 3 HOH 341 746 274 HOH WAT A . C 3 HOH 342 747 275 HOH WAT A . C 3 HOH 343 748 276 HOH WAT A . C 3 HOH 344 749 277 HOH WAT A . C 3 HOH 345 750 278 HOH WAT A . C 3 HOH 346 751 279 HOH WAT A . C 3 HOH 347 752 280 HOH WAT A . C 3 HOH 348 753 281 HOH WAT A . C 3 HOH 349 754 282 HOH WAT A . C 3 HOH 350 755 283 HOH WAT A . C 3 HOH 351 756 284 HOH WAT A . C 3 HOH 352 757 285 HOH WAT A . C 3 HOH 353 758 286 HOH WAT A . C 3 HOH 354 759 287 HOH WAT A . C 3 HOH 355 760 288 HOH WAT A . C 3 HOH 356 761 289 HOH WAT A . C 3 HOH 357 762 290 HOH WAT A . C 3 HOH 358 763 291 HOH WAT A . C 3 HOH 359 764 292 HOH WAT A . C 3 HOH 360 765 293 HOH WAT A . C 3 HOH 361 766 294 HOH WAT A . C 3 HOH 362 767 295 HOH WAT A . C 3 HOH 363 768 296 HOH WAT A . C 3 HOH 364 769 297 HOH WAT A . C 3 HOH 365 770 298 HOH WAT A . C 3 HOH 366 771 299 HOH WAT A . C 3 HOH 367 772 300 HOH WAT A . C 3 HOH 368 773 301 HOH WAT A . C 3 HOH 369 774 302 HOH WAT A . C 3 HOH 370 775 303 HOH WAT A . C 3 HOH 371 776 304 HOH WAT A . C 3 HOH 372 777 305 HOH WAT A . C 3 HOH 373 778 306 HOH WAT A . C 3 HOH 374 779 307 HOH WAT A . C 3 HOH 375 780 308 HOH WAT A . C 3 HOH 376 781 309 HOH WAT A . C 3 HOH 377 782 310 HOH WAT A . C 3 HOH 378 783 311 HOH WAT A . C 3 HOH 379 784 312 HOH WAT A . C 3 HOH 380 785 313 HOH WAT A . C 3 HOH 381 786 314 HOH WAT A . C 3 HOH 382 787 315 HOH WAT A . C 3 HOH 383 788 316 HOH WAT A . C 3 HOH 384 789 317 HOH WAT A . C 3 HOH 385 790 318 HOH WAT A . C 3 HOH 386 791 319 HOH WAT A . C 3 HOH 387 792 320 HOH WAT A . C 3 HOH 388 793 321 HOH WAT A . C 3 HOH 389 794 322 HOH WAT A . C 3 HOH 390 795 323 HOH WAT A . C 3 HOH 391 796 324 HOH WAT A . C 3 HOH 392 797 325 HOH WAT A . C 3 HOH 393 798 326 HOH WAT A . C 3 HOH 394 799 327 HOH WAT A . C 3 HOH 395 800 328 HOH WAT A . C 3 HOH 396 801 329 HOH WAT A . C 3 HOH 397 802 330 HOH WAT A . C 3 HOH 398 803 331 HOH WAT A . C 3 HOH 399 804 332 HOH WAT A . C 3 HOH 400 805 333 HOH WAT A . C 3 HOH 401 806 334 HOH WAT A . C 3 HOH 402 807 335 HOH WAT A . C 3 HOH 403 808 336 HOH WAT A . C 3 HOH 404 809 337 HOH WAT A . C 3 HOH 405 810 338 HOH WAT A . C 3 HOH 406 811 339 HOH WAT A . C 3 HOH 407 812 340 HOH WAT A . C 3 HOH 408 813 341 HOH WAT A . C 3 HOH 409 814 342 HOH WAT A . C 3 HOH 410 815 343 HOH WAT A . C 3 HOH 411 816 344 HOH WAT A . C 3 HOH 412 817 345 HOH WAT A . C 3 HOH 413 818 346 HOH WAT A . C 3 HOH 414 819 347 HOH WAT A . C 3 HOH 415 820 348 HOH WAT A . C 3 HOH 416 821 349 HOH WAT A . C 3 HOH 417 822 350 HOH WAT A . C 3 HOH 418 823 351 HOH WAT A . C 3 HOH 419 824 352 HOH WAT A . C 3 HOH 420 825 353 HOH WAT A . C 3 HOH 421 826 354 HOH WAT A . C 3 HOH 422 827 355 HOH WAT A . C 3 HOH 423 828 356 HOH WAT A . C 3 HOH 424 829 357 HOH WAT A . C 3 HOH 425 830 358 HOH WAT A . C 3 HOH 426 831 359 HOH WAT A . C 3 HOH 427 832 360 HOH WAT A . C 3 HOH 428 833 361 HOH WAT A . C 3 HOH 429 834 362 HOH WAT A . C 3 HOH 430 835 363 HOH WAT A . C 3 HOH 431 836 364 HOH WAT A . C 3 HOH 432 837 365 HOH WAT A . C 3 HOH 433 838 366 HOH WAT A . C 3 HOH 434 839 367 HOH WAT A . C 3 HOH 435 840 368 HOH WAT A . C 3 HOH 436 841 369 HOH WAT A . C 3 HOH 437 842 370 HOH WAT A . C 3 HOH 438 843 371 HOH WAT A . C 3 HOH 439 844 372 HOH WAT A . C 3 HOH 440 845 373 HOH WAT A . C 3 HOH 441 846 374 HOH WAT A . C 3 HOH 442 847 375 HOH WAT A . C 3 HOH 443 848 376 HOH WAT A . C 3 HOH 444 849 377 HOH WAT A . C 3 HOH 445 850 378 HOH WAT A . C 3 HOH 446 851 379 HOH WAT A . C 3 HOH 447 852 380 HOH WAT A . C 3 HOH 448 853 381 HOH WAT A . C 3 HOH 449 854 382 HOH WAT A . C 3 HOH 450 855 383 HOH WAT A . C 3 HOH 451 856 384 HOH WAT A . C 3 HOH 452 857 385 HOH WAT A . C 3 HOH 453 858 386 HOH WAT A . C 3 HOH 454 859 387 HOH WAT A . C 3 HOH 455 860 388 HOH WAT A . C 3 HOH 456 861 389 HOH WAT A . C 3 HOH 457 862 390 HOH WAT A . C 3 HOH 458 863 391 HOH WAT A . C 3 HOH 459 864 392 HOH WAT A . C 3 HOH 460 865 393 HOH WAT A . C 3 HOH 461 866 394 HOH WAT A . C 3 HOH 462 867 395 HOH WAT A . C 3 HOH 463 868 396 HOH WAT A . C 3 HOH 464 869 397 HOH WAT A . C 3 HOH 465 870 398 HOH WAT A . C 3 HOH 466 871 399 HOH WAT A . C 3 HOH 467 872 400 HOH WAT A . C 3 HOH 468 873 401 HOH WAT A . C 3 HOH 469 874 402 HOH WAT A . C 3 HOH 470 875 403 HOH WAT A . C 3 HOH 471 876 404 HOH WAT A . C 3 HOH 472 877 405 HOH WAT A . C 3 HOH 473 878 406 HOH WAT A . C 3 HOH 474 879 407 HOH WAT A . C 3 HOH 475 880 408 HOH WAT A . C 3 HOH 476 881 409 HOH WAT A . C 3 HOH 477 882 410 HOH WAT A . C 3 HOH 478 883 411 HOH WAT A . C 3 HOH 479 884 412 HOH WAT A . C 3 HOH 480 885 413 HOH WAT A . C 3 HOH 481 886 414 HOH WAT A . C 3 HOH 482 887 415 HOH WAT A . C 3 HOH 483 888 416 HOH WAT A . C 3 HOH 484 889 417 HOH WAT A . C 3 HOH 485 890 418 HOH WAT A . C 3 HOH 486 891 419 HOH WAT A . C 3 HOH 487 892 420 HOH WAT A . C 3 HOH 488 893 421 HOH WAT A . C 3 HOH 489 894 422 HOH WAT A . C 3 HOH 490 895 423 HOH WAT A . C 3 HOH 491 896 424 HOH WAT A . C 3 HOH 492 897 425 HOH WAT A . C 3 HOH 493 898 426 HOH WAT A . C 3 HOH 494 899 427 HOH WAT A . C 3 HOH 495 900 428 HOH WAT A . #