data_3OAG # _entry.id 3OAG # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.281 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3OAG RCSB RCSB060868 WWPDB D_1000060868 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 3OAD . unspecified PDB 3OEC . unspecified PDB 3O9L . unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 3OAG _pdbx_database_status.recvd_initial_deposition_date 2010-08-05 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.pdb_format_compatible Y # _audit_author.name 'Prade, L.' _audit_author.pdbx_ordinal 1 # _citation.id primary _citation.title 'Design and optimization of new piperidines as renin inhibitors.' _citation.journal_abbrev Bioorg.Med.Chem.Lett. _citation.journal_volume 20 _citation.page_first 6286 _citation.page_last 6290 _citation.year 2010 _citation.journal_id_ASTM BMCLE8 _citation.country UK _citation.journal_id_ISSN 0960-894X _citation.journal_id_CSD 1127 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 20843686 _citation.pdbx_database_id_DOI 10.1016/j.bmcl.2010.08.086 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Corminboeuf, O.' 1 primary 'Bezencon, O.' 2 primary 'Grisostomi, C.' 3 primary 'Remen, L.' 4 primary 'Richard-Bildstein, S.' 5 primary 'Bur, D.' 6 primary 'Prade, L.' 7 primary 'Hess, P.' 8 primary 'Strickner, P.' 9 primary 'Fischli, W.' 10 primary 'Steiner, B.' 11 primary 'Treiber, A.' 12 # _cell.entry_id 3OAG _cell.length_a 66.570 _cell.length_b 93.633 _cell.length_c 117.896 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 3OAG _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man Renin 18225.455 2 3.4.23.15 ? 'Renin (unp residue 67-232)' ? 2 polymer man Renin 19430.055 2 3.4.23.15 ? 'Renin (unp residue 237-406)' ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 2 ? ? ? ? 4 non-polymer syn ;(3R,4S)-N-{2-chloro-5-[(cyclopropylamino)methyl]benzyl}-N-cyclopropyl-4-{6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]pyridin-3-yl}piperidine-3-carboxamide ; 658.057 2 ? ? ? ? 5 water nat water 18.015 180 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;LTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELT LRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSF YYNRDS ; ;LTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELT LRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSF YYNRDS ; A,C ? 2 'polypeptide(L)' no no ;SLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKK RLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRR NNRIGFALARHHHHHH ; ;SLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKK RLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRR NNRIGFALARHHHHHH ; B,D ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 LEU n 1 2 THR n 1 3 LEU n 1 4 GLY n 1 5 ASN n 1 6 THR n 1 7 THR n 1 8 SER n 1 9 SER n 1 10 VAL n 1 11 ILE n 1 12 LEU n 1 13 THR n 1 14 ASN n 1 15 TYR n 1 16 MET n 1 17 ASP n 1 18 THR n 1 19 GLN n 1 20 TYR n 1 21 TYR n 1 22 GLY n 1 23 GLU n 1 24 ILE n 1 25 GLY n 1 26 ILE n 1 27 GLY n 1 28 THR n 1 29 PRO n 1 30 PRO n 1 31 GLN n 1 32 THR n 1 33 PHE n 1 34 LYS n 1 35 VAL n 1 36 VAL n 1 37 PHE n 1 38 ASP n 1 39 THR n 1 40 GLY n 1 41 SER n 1 42 SER n 1 43 ASN n 1 44 VAL n 1 45 TRP n 1 46 VAL n 1 47 PRO n 1 48 SER n 1 49 SER n 1 50 LYS n 1 51 CYS n 1 52 SER n 1 53 ARG n 1 54 LEU n 1 55 TYR n 1 56 THR n 1 57 ALA n 1 58 CYS n 1 59 VAL n 1 60 TYR n 1 61 HIS n 1 62 LYS n 1 63 LEU n 1 64 PHE n 1 65 ASP n 1 66 ALA n 1 67 SER n 1 68 ASP n 1 69 SER n 1 70 SER n 1 71 SER n 1 72 TYR n 1 73 LYS n 1 74 HIS n 1 75 ASN n 1 76 GLY n 1 77 THR n 1 78 GLU n 1 79 LEU n 1 80 THR n 1 81 LEU n 1 82 ARG n 1 83 TYR n 1 84 SER n 1 85 THR n 1 86 GLY n 1 87 THR n 1 88 VAL n 1 89 SER n 1 90 GLY n 1 91 PHE n 1 92 LEU n 1 93 SER n 1 94 GLN n 1 95 ASP n 1 96 ILE n 1 97 ILE n 1 98 THR n 1 99 VAL n 1 100 GLY n 1 101 GLY n 1 102 ILE n 1 103 THR n 1 104 VAL n 1 105 THR n 1 106 GLN n 1 107 MET n 1 108 PHE n 1 109 GLY n 1 110 GLU n 1 111 VAL n 1 112 THR n 1 113 GLU n 1 114 MET n 1 115 PRO n 1 116 ALA n 1 117 LEU n 1 118 PRO n 1 119 PHE n 1 120 MET n 1 121 LEU n 1 122 ALA n 1 123 GLU n 1 124 PHE n 1 125 ASP n 1 126 GLY n 1 127 VAL n 1 128 VAL n 1 129 GLY n 1 130 MET n 1 131 GLY n 1 132 PHE n 1 133 ILE n 1 134 GLU n 1 135 GLN n 1 136 ALA n 1 137 ILE n 1 138 GLY n 1 139 ARG n 1 140 VAL n 1 141 THR n 1 142 PRO n 1 143 ILE n 1 144 PHE n 1 145 ASP n 1 146 ASN n 1 147 ILE n 1 148 ILE n 1 149 SER n 1 150 GLN n 1 151 GLY n 1 152 VAL n 1 153 LEU n 1 154 LYS n 1 155 GLU n 1 156 ASP n 1 157 VAL n 1 158 PHE n 1 159 SER n 1 160 PHE n 1 161 TYR n 1 162 TYR n 1 163 ASN n 1 164 ARG n 1 165 ASP n 1 166 SER n 2 1 SER n 2 2 LEU n 2 3 GLY n 2 4 GLY n 2 5 GLN n 2 6 ILE n 2 7 VAL n 2 8 LEU n 2 9 GLY n 2 10 GLY n 2 11 SER n 2 12 ASP n 2 13 PRO n 2 14 GLN n 2 15 HIS n 2 16 TYR n 2 17 GLU n 2 18 GLY n 2 19 ASN n 2 20 PHE n 2 21 HIS n 2 22 TYR n 2 23 ILE n 2 24 ASN n 2 25 LEU n 2 26 ILE n 2 27 LYS n 2 28 THR n 2 29 GLY n 2 30 VAL n 2 31 TRP n 2 32 GLN n 2 33 ILE n 2 34 GLN n 2 35 MET n 2 36 LYS n 2 37 GLY n 2 38 VAL n 2 39 SER n 2 40 VAL n 2 41 GLY n 2 42 SER n 2 43 SER n 2 44 THR n 2 45 LEU n 2 46 LEU n 2 47 CYS n 2 48 GLU n 2 49 ASP n 2 50 GLY n 2 51 CYS n 2 52 LEU n 2 53 ALA n 2 54 LEU n 2 55 VAL n 2 56 ASP n 2 57 THR n 2 58 GLY n 2 59 ALA n 2 60 SER n 2 61 TYR n 2 62 ILE n 2 63 SER n 2 64 GLY n 2 65 SER n 2 66 THR n 2 67 SER n 2 68 SER n 2 69 ILE n 2 70 GLU n 2 71 LYS n 2 72 LEU n 2 73 MET n 2 74 GLU n 2 75 ALA n 2 76 LEU n 2 77 GLY n 2 78 ALA n 2 79 LYS n 2 80 LYS n 2 81 ARG n 2 82 LEU n 2 83 PHE n 2 84 ASP n 2 85 TYR n 2 86 VAL n 2 87 VAL n 2 88 LYS n 2 89 CYS n 2 90 ASN n 2 91 GLU n 2 92 GLY n 2 93 PRO n 2 94 THR n 2 95 LEU n 2 96 PRO n 2 97 ASP n 2 98 ILE n 2 99 SER n 2 100 PHE n 2 101 HIS n 2 102 LEU n 2 103 GLY n 2 104 GLY n 2 105 LYS n 2 106 GLU n 2 107 TYR n 2 108 THR n 2 109 LEU n 2 110 THR n 2 111 SER n 2 112 ALA n 2 113 ASP n 2 114 TYR n 2 115 VAL n 2 116 PHE n 2 117 GLN n 2 118 GLU n 2 119 SER n 2 120 TYR n 2 121 SER n 2 122 SER n 2 123 LYS n 2 124 LYS n 2 125 LEU n 2 126 CYS n 2 127 THR n 2 128 LEU n 2 129 ALA n 2 130 ILE n 2 131 HIS n 2 132 ALA n 2 133 MET n 2 134 ASP n 2 135 ILE n 2 136 PRO n 2 137 PRO n 2 138 PRO n 2 139 THR n 2 140 GLY n 2 141 PRO n 2 142 THR n 2 143 TRP n 2 144 ALA n 2 145 LEU n 2 146 GLY n 2 147 ALA n 2 148 THR n 2 149 PHE n 2 150 ILE n 2 151 ARG n 2 152 LYS n 2 153 PHE n 2 154 TYR n 2 155 THR n 2 156 GLU n 2 157 PHE n 2 158 ASP n 2 159 ARG n 2 160 ARG n 2 161 ASN n 2 162 ASN n 2 163 ARG n 2 164 ILE n 2 165 GLY n 2 166 PHE n 2 167 ALA n 2 168 LEU n 2 169 ALA n 2 170 ARG n 2 171 HIS n 2 172 HIS n 2 173 HIS n 2 174 HIS n 2 175 HIS n 2 176 HIS n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample ? ? ? human ? REN ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Cricetulus griseus' 10029 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample ? ? ? human ? REN ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Cricetulus griseus' 10029 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin _struct_ref.pdbx_db_isoform 1 UNP RENI_HUMAN P00797 1 ;LTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELT LRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSF YYNRDS ; 67 ? 2 UNP RENI_HUMAN P00797 2 ;SLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKK RLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRR NNRIGFALAR ; 237 ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 3OAG A 1 ? 166 ? P00797 67 ? 232 ? 1 166 2 2 3OAG B 1 ? 170 ? P00797 237 ? 406 ? 171 340 3 1 3OAG C 1 ? 166 ? P00797 67 ? 232 ? 1 166 4 2 3OAG D 1 ? 170 ? P00797 237 ? 406 ? 171 340 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 2 3OAG HIS B 171 ? UNP P00797 ? ? 'EXPRESSION TAG' 341 1 2 3OAG HIS B 172 ? UNP P00797 ? ? 'EXPRESSION TAG' 342 2 2 3OAG HIS B 173 ? UNP P00797 ? ? 'EXPRESSION TAG' 343 3 2 3OAG HIS B 174 ? UNP P00797 ? ? 'EXPRESSION TAG' 344 4 2 3OAG HIS B 175 ? UNP P00797 ? ? 'EXPRESSION TAG' 345 5 2 3OAG HIS B 176 ? UNP P00797 ? ? 'EXPRESSION TAG' 346 6 4 3OAG HIS D 171 ? UNP P00797 ? ? 'EXPRESSION TAG' 341 7 4 3OAG HIS D 172 ? UNP P00797 ? ? 'EXPRESSION TAG' 342 8 4 3OAG HIS D 173 ? UNP P00797 ? ? 'EXPRESSION TAG' 343 9 4 3OAG HIS D 174 ? UNP P00797 ? ? 'EXPRESSION TAG' 344 10 4 3OAG HIS D 175 ? UNP P00797 ? ? 'EXPRESSION TAG' 345 11 4 3OAG HIS D 176 ? UNP P00797 ? ? 'EXPRESSION TAG' 346 12 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LPQ non-polymer . ;(3R,4S)-N-{2-chloro-5-[(cyclopropylamino)methyl]benzyl}-N-cyclopropyl-4-{6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]pyridin-3-yl}piperidine-3-carboxamide ; ;(3'R,4'S)-6-[2-(2,6-Dichloro-4-methyl-phenoxy)-ethoxy]-1',2',3',4',5',6'-hexahydro-[3,4']bipyridinyl-3'-carboxylic acid (2-chloro-5-cyclopropylaminomethyl-benzyl)-cyclopropyl-amide ; 'C34 H39 Cl3 N4 O3' 658.057 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 3OAG _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.45 _exptl_crystal.density_percent_sol 49.69 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 4.75 _exptl_crystal_grow.pdbx_details ;20-30% PEG4000 0.6M KCl or NaCl, pH 4.75, VAPOR DIFFUSION, SITTING DROP, temperature 293K ; _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'MARMOSAIC 225 mm CCD' _diffrn_detector.pdbx_collection_date 2006-08-20 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'si 111' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.0 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'SLS BEAMLINE X06SA' _diffrn_source.pdbx_synchrotron_site SLS _diffrn_source.pdbx_synchrotron_beamline X06SA _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.0 # _reflns.entry_id 3OAG _reflns.observed_criterion_sigma_I 0 _reflns.observed_criterion_sigma_F 0 _reflns.d_resolution_low 58.0 _reflns.d_resolution_high 2.3 _reflns.number_obs 28739 _reflns.number_all 35174 _reflns.percent_possible_obs 85.9 _reflns.pdbx_Rmerge_I_obs 0.082 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 6.9 _reflns.B_iso_Wilson_estimate 36 _reflns.pdbx_redundancy 3.3 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 # _reflns_shell.d_res_high 2.3 _reflns_shell.d_res_low 2.4 _reflns_shell.percent_possible_all 33.4 _reflns_shell.Rmerge_I_obs ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs ? _reflns_shell.pdbx_redundancy ? _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_diffrn_id ? _reflns_shell.pdbx_ordinal 1 # _refine.entry_id 3OAG _refine.ls_number_reflns_obs 27245 _refine.ls_number_reflns_all 28739 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 58.0 _refine.ls_d_res_high 2.30 _refine.ls_percent_reflns_obs 85.76 _refine.ls_R_factor_obs 0.202 _refine.ls_R_factor_all 0.202 _refine.ls_R_factor_R_work 0.19885 _refine.ls_R_factor_R_free 0.25935 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.0 _refine.ls_number_reflns_R_free 1445 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.938 _refine.correlation_coeff_Fo_to_Fc_free 0.903 _refine.B_iso_mean 42.460 _refine.aniso_B[1][1] -0.76 _refine.aniso_B[2][2] 2.86 _refine.aniso_B[3][3] -2.11 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details 'BABINET MODEL WITH MASK' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.40 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R_Free 0.286 _refine.overall_SU_ML 0.122 _refine.overall_SU_B 4.861 _refine.overall_SU_R_Cruickshank_DPI ? _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_overall_ESU_R ? _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 5161 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 116 _refine_hist.number_atoms_solvent 180 _refine_hist.number_atoms_total 5457 _refine_hist.d_res_high 2.30 _refine_hist.d_res_low 58.0 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.009 0.022 ? 5429 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.293 1.978 ? 7376 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 7.274 5.000 ? 667 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 35.842 23.982 ? 221 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 16.832 15.000 ? 856 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 16.353 15.000 ? 20 'X-RAY DIFFRACTION' ? r_chiral_restr 0.081 0.200 ? 821 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.004 0.020 ? 4074 'X-RAY DIFFRACTION' ? r_nbd_refined 0.205 0.200 ? 2348 'X-RAY DIFFRACTION' ? r_nbtor_refined 0.309 0.200 ? 3660 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 0.129 0.200 ? 297 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 0.201 0.200 ? 46 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 0.133 0.200 ? 10 'X-RAY DIFFRACTION' ? r_mcbond_it 1.504 3.000 ? 3393 'X-RAY DIFFRACTION' ? r_mcangle_it 2.439 5.000 ? 5346 'X-RAY DIFFRACTION' ? r_scbond_it 1.367 3.000 ? 2352 'X-RAY DIFFRACTION' ? r_scangle_it 2.158 5.000 ? 2018 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.300 _refine_ls_shell.d_res_low 2.360 _refine_ls_shell.number_reflns_R_work 416 _refine_ls_shell.R_factor_R_work 0.228 _refine_ls_shell.percent_reflns_obs 18.18 _refine_ls_shell.R_factor_R_free 0.328 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 25 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 3OAG _struct.title 'Design and optimization of new piperidines as renin inhibitors' _struct.pdbx_descriptor 'Renin (E.C.3.4.23.15)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3OAG _struct_keywords.pdbx_keywords 'HYDROLASE / HYDROLASE INHIBITOR' _struct_keywords.text 'Hydrolase, Protease, Glycosilation, Blood, HYDROLASE - HYDROLASE INHIBITOR complex' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 1 ? D N N 2 ? E N N 3 ? F N N 4 ? G N N 3 ? H N N 4 ? I N N 5 ? J N N 5 ? K N N 5 ? L N N 5 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 TYR A 55 ? TYR A 60 ? TYR A 55 TYR A 60 1 ? 6 HELX_P HELX_P2 2 ASP A 65 ? SER A 69 ? ASP A 65 SER A 69 5 ? 5 HELX_P HELX_P3 3 PRO A 118 ? ALA A 122 ? PRO A 118 ALA A 122 5 ? 5 HELX_P HELX_P4 4 PHE A 132 ? VAL A 140 ? PHE A 132 VAL A 140 5 ? 9 HELX_P HELX_P5 5 PRO A 142 ? GLN A 150 ? PRO A 142 GLN A 150 1 ? 9 HELX_P HELX_P6 6 ASP B 12 ? GLN B 14 ? ASP B 182 GLN B 184 5 ? 3 HELX_P HELX_P7 7 SER B 65 ? GLY B 77 ? SER B 235 GLY B 247 1 ? 13 HELX_P HELX_P8 8 GLU B 91 ? LEU B 95 ? GLU B 261 LEU B 265 5 ? 5 HELX_P HELX_P9 9 THR B 110 ? VAL B 115 ? THR B 280 VAL B 285 1 ? 6 HELX_P HELX_P10 10 GLY B 146 ? LYS B 152 ? GLY B 316 LYS B 322 1 ? 7 HELX_P HELX_P11 11 TYR C 55 ? TYR C 60 ? TYR C 55 TYR C 60 1 ? 6 HELX_P HELX_P12 12 ASP C 65 ? SER C 69 ? ASP C 65 SER C 69 5 ? 5 HELX_P HELX_P13 13 PRO C 118 ? ALA C 122 ? PRO C 118 ALA C 122 5 ? 5 HELX_P HELX_P14 14 PHE C 132 ? VAL C 140 ? PHE C 132 VAL C 140 5 ? 9 HELX_P HELX_P15 15 PRO C 142 ? GLN C 150 ? PRO C 142 GLN C 150 1 ? 9 HELX_P HELX_P16 16 ASP D 12 ? GLN D 14 ? ASP D 182 GLN D 184 5 ? 3 HELX_P HELX_P17 17 SER D 65 ? GLU D 74 ? SER D 235 GLU D 244 1 ? 10 HELX_P HELX_P18 18 ASN D 90 ? GLY D 92 ? ASN D 260 GLY D 262 5 ? 3 HELX_P HELX_P19 19 THR D 110 ? VAL D 115 ? THR D 280 VAL D 285 1 ? 6 HELX_P HELX_P20 20 GLY D 146 ? LYS D 152 ? GLY D 316 LYS D 322 1 ? 7 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 51 SG ? ? ? 1_555 A CYS 58 SG ? ? A CYS 51 A CYS 58 1_555 ? ? ? ? ? ? ? 2.009 ? disulf2 disulf ? ? B CYS 47 SG ? ? ? 1_555 B CYS 51 SG ? ? B CYS 217 B CYS 221 1_555 ? ? ? ? ? ? ? 2.049 ? disulf3 disulf ? ? B CYS 89 SG ? ? ? 1_555 B CYS 126 SG ? ? B CYS 259 B CYS 296 1_555 ? ? ? ? ? ? ? 2.052 ? disulf4 disulf ? ? C CYS 51 SG ? ? ? 1_555 C CYS 58 SG ? ? C CYS 51 C CYS 58 1_555 ? ? ? ? ? ? ? 2.030 ? disulf5 disulf ? ? D CYS 47 SG ? ? ? 1_555 D CYS 51 SG ? ? D CYS 217 D CYS 221 1_555 ? ? ? ? ? ? ? 2.032 ? disulf6 disulf ? ? D CYS 89 SG ? ? ? 1_555 D CYS 126 SG ? ? D CYS 259 D CYS 296 1_555 ? ? ? ? ? ? ? 2.048 ? covale1 covale ? ? A ASN 75 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 75 A NAG 166 1_555 ? ? ? ? ? ? ? 1.453 ? covale2 covale ? ? C ASN 5 ND2 ? ? ? 1_555 G NAG . C1 ? ? C ASN 5 C NAG 166 1_555 ? ? ? ? ? ? ? 1.440 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 THR 28 A . ? THR 28 A PRO 29 A ? PRO 29 A 1 -6.18 2 LEU 117 A . ? LEU 117 A PRO 118 A ? PRO 118 A 1 -0.45 3 PRO 137 B . ? PRO 307 B PRO 138 B ? PRO 308 B 1 8.65 4 GLY 140 B . ? GLY 310 B PRO 141 B ? PRO 311 B 1 -4.31 5 THR 28 C . ? THR 28 C PRO 29 C ? PRO 29 C 1 4.07 6 LEU 117 C . ? LEU 117 C PRO 118 C ? PRO 118 C 1 -0.20 7 PRO 137 D . ? PRO 307 D PRO 138 D ? PRO 308 D 1 4.57 8 GLY 140 D . ? GLY 310 D PRO 141 D ? PRO 311 D 1 4.36 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 9 ? B ? 13 ? C ? 5 ? D ? 4 ? E ? 3 ? F ? 9 ? G ? 13 ? H ? 5 ? I ? 4 ? J ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel A 4 5 ? anti-parallel A 5 6 ? anti-parallel A 6 7 ? anti-parallel A 7 8 ? anti-parallel A 8 9 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? parallel B 4 5 ? anti-parallel B 5 6 ? parallel B 6 7 ? anti-parallel B 7 8 ? anti-parallel B 8 9 ? anti-parallel B 9 10 ? anti-parallel B 10 11 ? anti-parallel B 11 12 ? anti-parallel B 12 13 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? parallel C 3 4 ? anti-parallel C 4 5 ? parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel F 4 5 ? anti-parallel F 5 6 ? anti-parallel F 6 7 ? anti-parallel F 7 8 ? anti-parallel F 8 9 ? anti-parallel G 1 2 ? anti-parallel G 2 3 ? anti-parallel G 3 4 ? parallel G 4 5 ? anti-parallel G 5 6 ? parallel G 6 7 ? anti-parallel G 7 8 ? anti-parallel G 8 9 ? anti-parallel G 9 10 ? anti-parallel G 10 11 ? anti-parallel G 11 12 ? anti-parallel G 12 13 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? parallel H 3 4 ? anti-parallel H 4 5 ? parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 LYS A 73 ? TYR A 83 ? LYS A 73 TYR A 83 A 2 GLY A 86 ? VAL A 99 ? GLY A 86 VAL A 99 A 3 GLN A 19 ? ILE A 26 ? GLN A 19 ILE A 26 A 4 SER A 8 ? TYR A 15 ? SER A 8 TYR A 15 A 5 GLY B 4 ? LEU B 8 ? GLY B 174 LEU B 178 A 6 VAL A 157 ? TYR A 162 ? VAL A 157 TYR A 162 A 7 PHE B 153 ? ASP B 158 ? PHE B 323 ASP B 328 A 8 ARG B 163 ? ALA B 169 ? ARG B 333 ALA B 339 A 9 TYR B 16 ? ASN B 24 ? TYR B 186 ASN B 194 B 1 LYS A 73 ? TYR A 83 ? LYS A 73 TYR A 83 B 2 GLY A 86 ? VAL A 99 ? GLY A 86 VAL A 99 B 3 ILE A 102 ? GLU A 113 ? ILE A 102 GLU A 113 B 4 VAL A 44 ? PRO A 47 ? VAL A 44 PRO A 47 B 5 GLY A 126 ? GLY A 129 ? GLY A 126 GLY A 129 B 6 GLN A 31 ? ASP A 38 ? GLN A 31 ASP A 38 B 7 GLN A 19 ? ILE A 26 ? GLN A 19 ILE A 26 B 8 SER A 8 ? TYR A 15 ? SER A 8 TYR A 15 B 9 GLY B 4 ? LEU B 8 ? GLY B 174 LEU B 178 B 10 VAL A 157 ? TYR A 162 ? VAL A 157 TYR A 162 B 11 PHE B 153 ? ASP B 158 ? PHE B 323 ASP B 328 B 12 ARG B 163 ? ALA B 169 ? ARG B 333 ALA B 339 B 13 TYR B 16 ? ASN B 24 ? TYR B 186 ASN B 194 C 1 GLN B 32 ? MET B 35 ? GLN B 202 MET B 205 C 2 CYS B 51 ? VAL B 55 ? CYS B 221 VAL B 225 C 3 TRP B 143 ? LEU B 145 ? TRP B 313 LEU B 315 C 4 ILE B 62 ? GLY B 64 ? ILE B 232 GLY B 234 C 5 ILE B 130 ? ALA B 132 ? ILE B 300 ALA B 302 D 1 SER B 43 ? LEU B 46 ? SER B 213 LEU B 216 D 2 VAL B 38 ? VAL B 40 ? VAL B 208 VAL B 210 D 3 ILE B 98 ? LEU B 102 ? ILE B 268 LEU B 272 D 4 LYS B 105 ? LEU B 109 ? LYS B 275 LEU B 279 E 1 LYS B 79 ? LYS B 80 ? LYS B 249 LYS B 250 E 2 TYR B 85 ? LYS B 88 ? TYR B 255 LYS B 258 E 3 LEU B 125 ? THR B 127 ? LEU B 295 THR B 297 F 1 LYS C 73 ? TYR C 83 ? LYS C 73 TYR C 83 F 2 GLY C 86 ? VAL C 99 ? GLY C 86 VAL C 99 F 3 GLN C 19 ? ILE C 26 ? GLN C 19 ILE C 26 F 4 SER C 8 ? TYR C 15 ? SER C 8 TYR C 15 F 5 GLY D 4 ? LEU D 8 ? GLY D 174 LEU D 178 F 6 VAL C 157 ? TYR C 162 ? VAL C 157 TYR C 162 F 7 PHE D 153 ? ASP D 158 ? PHE D 323 ASP D 328 F 8 ARG D 163 ? ALA D 169 ? ARG D 333 ALA D 339 F 9 TYR D 16 ? ASN D 24 ? TYR D 186 ASN D 194 G 1 LYS C 73 ? TYR C 83 ? LYS C 73 TYR C 83 G 2 GLY C 86 ? VAL C 99 ? GLY C 86 VAL C 99 G 3 ILE C 102 ? GLU C 113 ? ILE C 102 GLU C 113 G 4 VAL C 44 ? PRO C 47 ? VAL C 44 PRO C 47 G 5 GLY C 126 ? GLY C 129 ? GLY C 126 GLY C 129 G 6 GLN C 31 ? ASP C 38 ? GLN C 31 ASP C 38 G 7 GLN C 19 ? ILE C 26 ? GLN C 19 ILE C 26 G 8 SER C 8 ? TYR C 15 ? SER C 8 TYR C 15 G 9 GLY D 4 ? LEU D 8 ? GLY D 174 LEU D 178 G 10 VAL C 157 ? TYR C 162 ? VAL C 157 TYR C 162 G 11 PHE D 153 ? ASP D 158 ? PHE D 323 ASP D 328 G 12 ARG D 163 ? ALA D 169 ? ARG D 333 ALA D 339 G 13 TYR D 16 ? ASN D 24 ? TYR D 186 ASN D 194 H 1 GLN D 32 ? MET D 35 ? GLN D 202 MET D 205 H 2 CYS D 51 ? VAL D 55 ? CYS D 221 VAL D 225 H 3 TRP D 143 ? LEU D 145 ? TRP D 313 LEU D 315 H 4 ILE D 62 ? GLY D 64 ? ILE D 232 GLY D 234 H 5 ILE D 130 ? ALA D 132 ? ILE D 300 ALA D 302 I 1 SER D 43 ? LEU D 46 ? SER D 213 LEU D 216 I 2 VAL D 38 ? VAL D 40 ? VAL D 208 VAL D 210 I 3 ILE D 98 ? LEU D 102 ? ILE D 268 LEU D 272 I 4 LYS D 105 ? LEU D 109 ? LYS D 275 LEU D 279 J 1 LYS D 79 ? LYS D 80 ? LYS D 249 LYS D 250 J 2 TYR D 85 ? LYS D 88 ? TYR D 255 LYS D 258 J 3 LEU D 125 ? THR D 127 ? LEU D 295 THR D 297 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N LEU A 81 ? N LEU A 81 O VAL A 88 ? O VAL A 88 A 2 3 O THR A 98 ? O THR A 98 N GLY A 25 ? N GLY A 25 A 3 4 O TYR A 21 ? O TYR A 21 N THR A 13 ? N THR A 13 A 4 5 N SER A 8 ? N SER A 8 O LEU B 8 ? O LEU B 178 A 5 6 O GLN B 5 ? O GLN B 175 N TYR A 161 ? N TYR A 161 A 6 7 N PHE A 158 ? N PHE A 158 O PHE B 157 ? O PHE B 327 A 7 8 N GLU B 156 ? N GLU B 326 O GLY B 165 ? O GLY B 335 A 8 9 O LEU B 168 ? O LEU B 338 N GLU B 17 ? N GLU B 187 B 1 2 N LEU A 81 ? N LEU A 81 O VAL A 88 ? O VAL A 88 B 2 3 N ILE A 97 ? N ILE A 97 O VAL A 104 ? O VAL A 104 B 3 4 O GLY A 109 ? O GLY A 109 N VAL A 44 ? N VAL A 44 B 4 5 N TRP A 45 ? N TRP A 45 O VAL A 127 ? O VAL A 127 B 5 6 O VAL A 128 ? O VAL A 128 N VAL A 36 ? N VAL A 36 B 6 7 O VAL A 35 ? O VAL A 35 N GLY A 22 ? N GLY A 22 B 7 8 O TYR A 21 ? O TYR A 21 N THR A 13 ? N THR A 13 B 8 9 N SER A 8 ? N SER A 8 O LEU B 8 ? O LEU B 178 B 9 10 O GLN B 5 ? O GLN B 175 N TYR A 161 ? N TYR A 161 B 10 11 N PHE A 158 ? N PHE A 158 O PHE B 157 ? O PHE B 327 B 11 12 N GLU B 156 ? N GLU B 326 O GLY B 165 ? O GLY B 335 B 12 13 O LEU B 168 ? O LEU B 338 N GLU B 17 ? N GLU B 187 C 1 2 N MET B 35 ? N MET B 205 O CYS B 51 ? O CYS B 221 C 2 3 N LEU B 54 ? N LEU B 224 O LEU B 145 ? O LEU B 315 C 3 4 O ALA B 144 ? O ALA B 314 N SER B 63 ? N SER B 233 C 4 5 N ILE B 62 ? N ILE B 232 O HIS B 131 ? O HIS B 301 D 1 2 O LEU B 46 ? O LEU B 216 N VAL B 38 ? N VAL B 208 D 2 3 N SER B 39 ? N SER B 209 O SER B 99 ? O SER B 269 D 3 4 N ILE B 98 ? N ILE B 268 O LEU B 109 ? O LEU B 279 E 1 2 N LYS B 79 ? N LYS B 249 O VAL B 86 ? O VAL B 256 E 2 3 N VAL B 87 ? N VAL B 257 O CYS B 126 ? O CYS B 296 F 1 2 N LEU C 81 ? N LEU C 81 O VAL C 88 ? O VAL C 88 F 2 3 O THR C 98 ? O THR C 98 N GLY C 25 ? N GLY C 25 F 3 4 O GLN C 19 ? O GLN C 19 N TYR C 15 ? N TYR C 15 F 4 5 N SER C 8 ? N SER C 8 O LEU D 8 ? O LEU D 178 F 5 6 O GLN D 5 ? O GLN D 175 N TYR C 161 ? N TYR C 161 F 6 7 N PHE C 158 ? N PHE C 158 O PHE D 157 ? O PHE D 327 F 7 8 N GLU D 156 ? N GLU D 326 O GLY D 165 ? O GLY D 335 F 8 9 O ILE D 164 ? O ILE D 334 N ILE D 23 ? N ILE D 193 G 1 2 N LEU C 81 ? N LEU C 81 O VAL C 88 ? O VAL C 88 G 2 3 N ILE C 97 ? N ILE C 97 O VAL C 104 ? O VAL C 104 G 3 4 O GLY C 109 ? O GLY C 109 N VAL C 44 ? N VAL C 44 G 4 5 N TRP C 45 ? N TRP C 45 O VAL C 127 ? O VAL C 127 G 5 6 O VAL C 128 ? O VAL C 128 N VAL C 36 ? N VAL C 36 G 6 7 O VAL C 35 ? O VAL C 35 N GLY C 22 ? N GLY C 22 G 7 8 O GLN C 19 ? O GLN C 19 N TYR C 15 ? N TYR C 15 G 8 9 N SER C 8 ? N SER C 8 O LEU D 8 ? O LEU D 178 G 9 10 O GLN D 5 ? O GLN D 175 N TYR C 161 ? N TYR C 161 G 10 11 N PHE C 158 ? N PHE C 158 O PHE D 157 ? O PHE D 327 G 11 12 N GLU D 156 ? N GLU D 326 O GLY D 165 ? O GLY D 335 G 12 13 O ILE D 164 ? O ILE D 334 N ILE D 23 ? N ILE D 193 H 1 2 N MET D 35 ? N MET D 205 O CYS D 51 ? O CYS D 221 H 2 3 N LEU D 54 ? N LEU D 224 O LEU D 145 ? O LEU D 315 H 3 4 O ALA D 144 ? O ALA D 314 N SER D 63 ? N SER D 233 H 4 5 N ILE D 62 ? N ILE D 232 O HIS D 131 ? O HIS D 301 I 1 2 O LEU D 46 ? O LEU D 216 N VAL D 38 ? N VAL D 208 I 2 3 N SER D 39 ? N SER D 209 O SER D 99 ? O SER D 269 I 3 4 N ILE D 98 ? N ILE D 268 O LEU D 109 ? O LEU D 279 J 1 2 N LYS D 79 ? N LYS D 249 O VAL D 86 ? O VAL D 256 J 2 3 N VAL D 87 ? N VAL D 257 O CYS D 126 ? O CYS D 296 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG C 166' AC2 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 166' AC3 Software ? ? ? ? 19 'BINDING SITE FOR RESIDUE LPQ A 167' AC4 Software ? ? ? ? 21 'BINDING SITE FOR RESIDUE LPQ C 167' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 3 ASN C 5 ? ASN C 5 . ? 1_555 ? 2 AC1 3 HOH K . ? HOH C 206 . ? 1_555 ? 3 AC1 3 HOH K . ? HOH C 212 . ? 1_555 ? 4 AC2 2 ASN A 75 ? ASN A 75 . ? 1_555 ? 5 AC2 2 THR A 77 ? THR A 77 . ? 1_555 ? 6 AC3 19 THR A 18 ? THR A 18 . ? 1_555 ? 7 AC3 19 ASP A 38 ? ASP A 38 . ? 1_555 ? 8 AC3 19 GLY A 40 ? GLY A 40 . ? 1_555 ? 9 AC3 19 TRP A 45 ? TRP A 45 . ? 1_555 ? 10 AC3 19 HIS A 61 ? HIS A 61 . ? 1_555 ? 11 AC3 19 LEU A 81 ? LEU A 81 . ? 1_555 ? 12 AC3 19 TYR A 83 ? TYR A 83 . ? 1_555 ? 13 AC3 19 VAL A 111 ? VAL A 111 . ? 1_555 ? 14 AC3 19 MET A 114 ? MET A 114 . ? 1_555 ? 15 AC3 19 PHE A 119 ? PHE A 119 . ? 1_555 ? 16 AC3 19 ALA A 122 ? ALA A 122 . ? 1_555 ? 17 AC3 19 PHE A 124 ? PHE A 124 . ? 1_555 ? 18 AC3 19 ASP A 125 ? ASP A 125 . ? 1_555 ? 19 AC3 19 VAL A 127 ? VAL A 127 . ? 1_555 ? 20 AC3 19 HOH I . ? HOH A 220 . ? 1_555 ? 21 AC3 19 ASP B 56 ? ASP B 226 . ? 1_555 ? 22 AC3 19 GLY B 58 ? GLY B 228 . ? 1_555 ? 23 AC3 19 ALA B 59 ? ALA B 229 . ? 1_555 ? 24 AC3 19 SER B 60 ? SER B 230 . ? 1_555 ? 25 AC4 21 THR C 18 ? THR C 18 . ? 1_555 ? 26 AC4 21 GLN C 19 ? GLN C 19 . ? 1_555 ? 27 AC4 21 TYR C 20 ? TYR C 20 . ? 1_555 ? 28 AC4 21 VAL C 36 ? VAL C 36 . ? 1_555 ? 29 AC4 21 ASP C 38 ? ASP C 38 . ? 1_555 ? 30 AC4 21 GLY C 40 ? GLY C 40 . ? 1_555 ? 31 AC4 21 TRP C 45 ? TRP C 45 . ? 1_555 ? 32 AC4 21 HIS C 61 ? HIS C 61 . ? 1_555 ? 33 AC4 21 LEU C 81 ? LEU C 81 . ? 1_555 ? 34 AC4 21 TYR C 83 ? TYR C 83 . ? 1_555 ? 35 AC4 21 VAL C 111 ? VAL C 111 . ? 1_555 ? 36 AC4 21 MET C 114 ? MET C 114 . ? 1_555 ? 37 AC4 21 PRO C 118 ? PRO C 118 . ? 1_555 ? 38 AC4 21 PHE C 119 ? PHE C 119 . ? 1_555 ? 39 AC4 21 PHE C 124 ? PHE C 124 . ? 1_555 ? 40 AC4 21 ASP C 125 ? ASP C 125 . ? 1_555 ? 41 AC4 21 VAL C 127 ? VAL C 127 . ? 1_555 ? 42 AC4 21 ASP D 56 ? ASP D 226 . ? 1_555 ? 43 AC4 21 GLY D 58 ? GLY D 228 . ? 1_555 ? 44 AC4 21 ALA D 59 ? ALA D 229 . ? 1_555 ? 45 AC4 21 SER D 60 ? SER D 230 . ? 1_555 ? # _database_PDB_matrix.entry_id 3OAG _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 3OAG _atom_sites.fract_transf_matrix[1][1] 0.015022 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.010680 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.008482 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C CL N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLY A 1 4 ? 13.850 -36.197 2.781 1.00 67.60 ? 4 GLY A N 1 ATOM 2 C CA . GLY A 1 4 ? 13.885 -34.873 3.479 1.00 68.72 ? 4 GLY A CA 1 ATOM 3 C C . GLY A 1 4 ? 14.433 -34.962 4.892 1.00 68.68 ? 4 GLY A C 1 ATOM 4 O O . GLY A 1 4 ? 13.773 -34.555 5.855 1.00 68.59 ? 4 GLY A O 1 ATOM 5 N N . ASN A 1 5 ? 15.650 -35.487 5.010 1.00 68.60 ? 5 ASN A N 1 ATOM 6 C CA . ASN A 1 5 ? 16.253 -35.772 6.312 1.00 68.16 ? 5 ASN A CA 1 ATOM 7 C C . ASN A 1 5 ? 17.670 -35.236 6.498 1.00 66.49 ? 5 ASN A C 1 ATOM 8 O O . ASN A 1 5 ? 18.366 -35.636 7.431 1.00 66.07 ? 5 ASN A O 1 ATOM 9 C CB . ASN A 1 5 ? 16.227 -37.283 6.587 1.00 69.89 ? 5 ASN A CB 1 ATOM 10 C CG . ASN A 1 5 ? 16.990 -38.102 5.543 1.00 72.00 ? 5 ASN A CG 1 ATOM 11 O OD1 . ASN A 1 5 ? 17.224 -37.652 4.414 1.00 72.74 ? 5 ASN A OD1 1 ATOM 12 N ND2 . ASN A 1 5 ? 17.371 -39.324 5.921 1.00 72.30 ? 5 ASN A ND2 1 ATOM 13 N N . THR A 1 6 ? 18.090 -34.321 5.626 1.00 65.07 ? 6 THR A N 1 ATOM 14 C CA . THR A 1 6 ? 19.473 -33.842 5.654 1.00 63.83 ? 6 THR A CA 1 ATOM 15 C C . THR A 1 6 ? 19.692 -32.496 6.347 1.00 61.87 ? 6 THR A C 1 ATOM 16 O O . THR A 1 6 ? 18.921 -31.548 6.172 1.00 61.39 ? 6 THR A O 1 ATOM 17 C CB . THR A 1 6 ? 20.132 -33.822 4.241 1.00 64.63 ? 6 THR A CB 1 ATOM 18 O OG1 . THR A 1 6 ? 19.199 -33.339 3.266 1.00 64.47 ? 6 THR A OG1 1 ATOM 19 C CG2 . THR A 1 6 ? 20.609 -35.232 3.843 1.00 65.17 ? 6 THR A CG2 1 ATOM 20 N N . THR A 1 7 ? 20.737 -32.463 7.172 1.00 59.07 ? 7 THR A N 1 ATOM 21 C CA . THR A 1 7 ? 21.384 -31.229 7.583 1.00 57.19 ? 7 THR A CA 1 ATOM 22 C C . THR A 1 7 ? 22.685 -31.150 6.790 1.00 56.09 ? 7 THR A C 1 ATOM 23 O O . THR A 1 7 ? 23.292 -32.179 6.482 1.00 57.15 ? 7 THR A O 1 ATOM 24 C CB . THR A 1 7 ? 21.689 -31.193 9.090 1.00 56.65 ? 7 THR A CB 1 ATOM 25 O OG1 . THR A 1 7 ? 22.222 -32.453 9.508 1.00 56.77 ? 7 THR A OG1 1 ATOM 26 C CG2 . THR A 1 7 ? 20.439 -30.914 9.882 1.00 57.25 ? 7 THR A CG2 1 ATOM 27 N N . SER A 1 8 ? 23.091 -29.939 6.430 1.00 53.34 ? 8 SER A N 1 ATOM 28 C CA . SER A 1 8 ? 24.304 -29.733 5.640 1.00 51.04 ? 8 SER A CA 1 ATOM 29 C C . SER A 1 8 ? 25.103 -28.566 6.211 1.00 48.71 ? 8 SER A C 1 ATOM 30 O O . SER A 1 8 ? 24.569 -27.477 6.444 1.00 48.70 ? 8 SER A O 1 ATOM 31 C CB . SER A 1 8 ? 23.958 -29.488 4.169 1.00 50.40 ? 8 SER A CB 1 ATOM 32 O OG . SER A 1 8 ? 25.119 -29.219 3.400 1.00 51.14 ? 8 SER A OG 1 ATOM 33 N N . SER A 1 9 ? 26.383 -28.799 6.450 1.00 45.94 ? 9 SER A N 1 ATOM 34 C CA . SER A 1 9 ? 27.206 -27.786 7.082 1.00 43.06 ? 9 SER A CA 1 ATOM 35 C C . SER A 1 9 ? 28.315 -27.281 6.162 1.00 40.43 ? 9 SER A C 1 ATOM 36 O O . SER A 1 9 ? 28.689 -27.946 5.193 1.00 40.72 ? 9 SER A O 1 ATOM 37 C CB . SER A 1 9 ? 27.779 -28.319 8.385 1.00 43.08 ? 9 SER A CB 1 ATOM 38 O OG . SER A 1 9 ? 28.868 -29.172 8.125 1.00 44.78 ? 9 SER A OG 1 ATOM 39 N N . VAL A 1 10 ? 28.812 -26.088 6.471 1.00 36.60 ? 10 VAL A N 1 ATOM 40 C CA . VAL A 1 10 ? 29.866 -25.444 5.709 1.00 33.86 ? 10 VAL A CA 1 ATOM 41 C C . VAL A 1 10 ? 30.849 -24.870 6.712 1.00 31.62 ? 10 VAL A C 1 ATOM 42 O O . VAL A 1 10 ? 30.469 -24.083 7.564 1.00 31.56 ? 10 VAL A O 1 ATOM 43 C CB . VAL A 1 10 ? 29.300 -24.288 4.804 1.00 34.27 ? 10 VAL A CB 1 ATOM 44 C CG1 . VAL A 1 10 ? 30.410 -23.601 4.000 1.00 33.30 ? 10 VAL A CG1 1 ATOM 45 C CG2 . VAL A 1 10 ? 28.203 -24.797 3.883 1.00 33.74 ? 10 VAL A CG2 1 ATOM 46 N N . ILE A 1 11 ? 32.105 -25.285 6.628 1.00 31.87 ? 11 ILE A N 1 ATOM 47 C CA . ILE A 1 11 ? 33.137 -24.743 7.503 1.00 32.15 ? 11 ILE A CA 1 ATOM 48 C C . ILE A 1 11 ? 33.437 -23.308 7.056 1.00 32.26 ? 11 ILE A C 1 ATOM 49 O O . ILE A 1 11 ? 33.525 -23.022 5.855 1.00 32.77 ? 11 ILE A O 1 ATOM 50 C CB . ILE A 1 11 ? 34.441 -25.600 7.499 1.00 32.70 ? 11 ILE A CB 1 ATOM 51 C CG1 . ILE A 1 11 ? 34.161 -27.049 7.904 1.00 34.57 ? 11 ILE A CG1 1 ATOM 52 C CG2 . ILE A 1 11 ? 35.499 -25.012 8.417 1.00 31.23 ? 11 ILE A CG2 1 ATOM 53 C CD1 . ILE A 1 11 ? 33.800 -27.242 9.376 1.00 36.89 ? 11 ILE A CD1 1 ATOM 54 N N . LEU A 1 12 ? 33.565 -22.411 8.028 1.00 29.31 ? 12 LEU A N 1 ATOM 55 C CA . LEU A 1 12 ? 33.897 -21.038 7.745 1.00 27.60 ? 12 LEU A CA 1 ATOM 56 C C . LEU A 1 12 ? 35.302 -20.726 8.206 1.00 27.84 ? 12 LEU A C 1 ATOM 57 O O . LEU A 1 12 ? 35.812 -21.325 9.153 1.00 26.91 ? 12 LEU A O 1 ATOM 58 C CB . LEU A 1 12 ? 32.910 -20.081 8.411 1.00 25.87 ? 12 LEU A CB 1 ATOM 59 C CG . LEU A 1 12 ? 31.434 -20.235 8.077 1.00 26.38 ? 12 LEU A CG 1 ATOM 60 C CD1 . LEU A 1 12 ? 30.605 -19.261 8.910 1.00 25.07 ? 12 LEU A CD1 1 ATOM 61 C CD2 . LEU A 1 12 ? 31.173 -20.050 6.580 1.00 25.89 ? 12 LEU A CD2 1 ATOM 62 N N . THR A 1 13 ? 35.924 -19.795 7.493 1.00 27.41 ? 13 THR A N 1 ATOM 63 C CA . THR A 1 13 ? 37.183 -19.206 7.888 1.00 26.95 ? 13 THR A CA 1 ATOM 64 C C . THR A 1 13 ? 36.883 -17.858 8.525 1.00 28.14 ? 13 THR A C 1 ATOM 65 O O . THR A 1 13 ? 36.088 -17.075 7.995 1.00 29.17 ? 13 THR A O 1 ATOM 66 C CB . THR A 1 13 ? 38.075 -19.000 6.665 1.00 24.42 ? 13 THR A CB 1 ATOM 67 O OG1 . THR A 1 13 ? 38.353 -20.274 6.101 1.00 23.36 ? 13 THR A OG1 1 ATOM 68 C CG2 . THR A 1 13 ? 39.396 -18.296 7.027 1.00 23.57 ? 13 THR A CG2 1 ATOM 69 N N . ASN A 1 14 ? 37.511 -17.615 9.668 1.00 28.37 ? 14 ASN A N 1 ATOM 70 C CA . ASN A 1 14 ? 37.472 -16.324 10.343 1.00 27.47 ? 14 ASN A CA 1 ATOM 71 C C . ASN A 1 14 ? 38.699 -15.507 9.954 1.00 27.94 ? 14 ASN A C 1 ATOM 72 O O . ASN A 1 14 ? 39.815 -15.857 10.318 1.00 26.75 ? 14 ASN A O 1 ATOM 73 C CB . ASN A 1 14 ? 37.458 -16.544 11.856 1.00 24.59 ? 14 ASN A CB 1 ATOM 74 C CG . ASN A 1 14 ? 37.577 -15.252 12.654 1.00 24.10 ? 14 ASN A CG 1 ATOM 75 O OD1 . ASN A 1 14 ? 37.667 -14.163 12.101 1.00 25.48 ? 14 ASN A OD1 1 ATOM 76 N ND2 . ASN A 1 14 ? 37.568 -15.378 13.969 1.00 22.58 ? 14 ASN A ND2 1 ATOM 77 N N . TYR A 1 15 ? 38.499 -14.423 9.214 1.00 29.83 ? 15 TYR A N 1 ATOM 78 C CA . TYR A 1 15 ? 39.582 -13.475 8.991 1.00 30.20 ? 15 TYR A CA 1 ATOM 79 C C . TYR A 1 15 ? 39.462 -12.296 9.965 1.00 32.14 ? 15 TYR A C 1 ATOM 80 O O . TYR A 1 15 ? 38.524 -11.499 9.865 1.00 32.80 ? 15 TYR A O 1 ATOM 81 C CB . TYR A 1 15 ? 39.584 -12.990 7.551 1.00 30.93 ? 15 TYR A CB 1 ATOM 82 C CG . TYR A 1 15 ? 40.604 -11.915 7.260 1.00 31.41 ? 15 TYR A CG 1 ATOM 83 C CD1 . TYR A 1 15 ? 41.955 -12.229 7.084 1.00 32.26 ? 15 TYR A CD1 1 ATOM 84 C CD2 . TYR A 1 15 ? 40.220 -10.593 7.138 1.00 31.86 ? 15 TYR A CD2 1 ATOM 85 C CE1 . TYR A 1 15 ? 42.895 -11.247 6.808 1.00 32.40 ? 15 TYR A CE1 1 ATOM 86 C CE2 . TYR A 1 15 ? 41.157 -9.589 6.858 1.00 33.29 ? 15 TYR A CE2 1 ATOM 87 C CZ . TYR A 1 15 ? 42.491 -9.925 6.700 1.00 32.72 ? 15 TYR A CZ 1 ATOM 88 O OH . TYR A 1 15 ? 43.417 -8.935 6.421 1.00 33.24 ? 15 TYR A OH 1 ATOM 89 N N . MET A 1 16 ? 40.402 -12.216 10.915 1.00 33.35 ? 16 MET A N 1 ATOM 90 C CA . MET A 1 16 ? 40.589 -11.047 11.793 1.00 35.05 ? 16 MET A CA 1 ATOM 91 C C . MET A 1 16 ? 39.348 -10.588 12.579 1.00 31.97 ? 16 MET A C 1 ATOM 92 O O . MET A 1 16 ? 39.204 -9.391 12.856 1.00 30.24 ? 16 MET A O 1 ATOM 93 C CB . MET A 1 16 ? 41.144 -9.865 10.985 1.00 37.41 ? 16 MET A CB 1 ATOM 94 C CG . MET A 1 16 ? 42.565 -10.063 10.437 1.00 42.81 ? 16 MET A CG 1 ATOM 95 S SD . MET A 1 16 ? 43.415 -8.488 10.113 1.00 46.03 ? 16 MET A SD 1 ATOM 96 C CE . MET A 1 16 ? 44.284 -8.239 11.661 1.00 47.76 ? 16 MET A CE 1 ATOM 97 N N . ASP A 1 17 ? 38.457 -11.531 12.914 1.00 29.89 ? 17 ASP A N 1 ATOM 98 C CA . ASP A 1 17 ? 37.178 -11.245 13.594 1.00 27.79 ? 17 ASP A CA 1 ATOM 99 C C . ASP A 1 17 ? 36.203 -10.331 12.815 1.00 28.98 ? 17 ASP A C 1 ATOM 100 O O . ASP A 1 17 ? 35.191 -9.871 13.365 1.00 27.82 ? 17 ASP A O 1 ATOM 101 C CB . ASP A 1 17 ? 37.425 -10.686 15.001 1.00 27.22 ? 17 ASP A CB 1 ATOM 102 C CG . ASP A 1 17 ? 37.709 -11.771 16.031 1.00 26.66 ? 17 ASP A CG 1 ATOM 103 O OD1 . ASP A 1 17 ? 37.588 -12.978 15.711 1.00 25.76 ? 17 ASP A OD1 1 ATOM 104 O OD2 . ASP A 1 17 ? 38.031 -11.408 17.183 1.00 24.58 ? 17 ASP A OD2 1 ATOM 105 N N . THR A 1 18 ? 36.485 -10.070 11.538 1.00 29.73 ? 18 THR A N 1 ATOM 106 C CA . THR A 1 18 ? 35.614 -9.161 10.756 1.00 29.74 ? 18 THR A CA 1 ATOM 107 C C . THR A 1 18 ? 34.999 -9.789 9.509 1.00 27.90 ? 18 THR A C 1 ATOM 108 O O . THR A 1 18 ? 33.991 -9.287 9.001 1.00 28.87 ? 18 THR A O 1 ATOM 109 C CB . THR A 1 18 ? 36.312 -7.830 10.370 1.00 29.39 ? 18 THR A CB 1 ATOM 110 O OG1 . THR A 1 18 ? 37.466 -8.101 9.572 1.00 32.35 ? 18 THR A OG1 1 ATOM 111 C CG2 . THR A 1 18 ? 36.734 -7.049 11.612 1.00 28.67 ? 18 THR A CG2 1 ATOM 112 N N . GLN A 1 19 ? 35.591 -10.875 9.019 1.00 24.31 ? 19 GLN A N 1 ATOM 113 C CA . GLN A 1 19 ? 35.075 -11.547 7.829 1.00 22.89 ? 19 GLN A CA 1 ATOM 114 C C . GLN A 1 19 ? 34.959 -13.052 8.053 1.00 23.96 ? 19 GLN A C 1 ATOM 115 O O . GLN A 1 19 ? 35.960 -13.738 8.340 1.00 25.15 ? 19 GLN A O 1 ATOM 116 C CB . GLN A 1 19 ? 35.959 -11.263 6.614 1.00 22.79 ? 19 GLN A CB 1 ATOM 117 C CG . GLN A 1 19 ? 36.104 -9.789 6.243 1.00 22.57 ? 19 GLN A CG 1 ATOM 118 C CD . GLN A 1 19 ? 37.121 -9.564 5.131 1.00 23.92 ? 19 GLN A CD 1 ATOM 119 O OE1 . GLN A 1 19 ? 37.377 -10.465 4.326 1.00 24.97 ? 19 GLN A OE1 1 ATOM 120 N NE2 . GLN A 1 19 ? 37.712 -8.356 5.081 1.00 21.89 ? 19 GLN A NE2 1 ATOM 121 N N . TYR A 1 20 ? 33.737 -13.564 7.930 1.00 22.86 ? 20 TYR A N 1 ATOM 122 C CA . TYR A 1 20 ? 33.512 -14.998 8.025 1.00 23.31 ? 20 TYR A CA 1 ATOM 123 C C . TYR A 1 20 ? 33.013 -15.537 6.688 1.00 23.55 ? 20 TYR A C 1 ATOM 124 O O . TYR A 1 20 ? 31.986 -15.089 6.172 1.00 23.44 ? 20 TYR A O 1 ATOM 125 C CB . TYR A 1 20 ? 32.539 -15.332 9.157 1.00 22.20 ? 20 TYR A CB 1 ATOM 126 C CG . TYR A 1 20 ? 33.057 -14.980 10.542 1.00 22.24 ? 20 TYR A CG 1 ATOM 127 C CD1 . TYR A 1 20 ? 33.563 -15.970 11.384 1.00 19.62 ? 20 TYR A CD1 1 ATOM 128 C CD2 . TYR A 1 20 ? 33.036 -13.650 11.007 1.00 21.36 ? 20 TYR A CD2 1 ATOM 129 C CE1 . TYR A 1 20 ? 34.048 -15.650 12.642 1.00 22.30 ? 20 TYR A CE1 1 ATOM 130 C CE2 . TYR A 1 20 ? 33.509 -13.317 12.275 1.00 21.80 ? 20 TYR A CE2 1 ATOM 131 C CZ . TYR A 1 20 ? 34.016 -14.320 13.088 1.00 22.65 ? 20 TYR A CZ 1 ATOM 132 O OH . TYR A 1 20 ? 34.495 -14.004 14.338 1.00 21.66 ? 20 TYR A OH 1 ATOM 133 N N . TYR A 1 21 ? 33.733 -16.510 6.142 1.00 23.97 ? 21 TYR A N 1 ATOM 134 C CA . TYR A 1 21 ? 33.438 -17.038 4.801 1.00 24.44 ? 21 TYR A CA 1 ATOM 135 C C . TYR A 1 21 ? 33.769 -18.509 4.664 1.00 23.77 ? 21 TYR A C 1 ATOM 136 O O . TYR A 1 21 ? 34.703 -19.001 5.314 1.00 23.36 ? 21 TYR A O 1 ATOM 137 C CB . TYR A 1 21 ? 34.196 -16.252 3.708 1.00 25.82 ? 21 TYR A CB 1 ATOM 138 C CG . TYR A 1 21 ? 35.695 -16.150 3.917 1.00 26.46 ? 21 TYR A CG 1 ATOM 139 C CD1 . TYR A 1 21 ? 36.255 -15.005 4.484 1.00 27.50 ? 21 TYR A CD1 1 ATOM 140 C CD2 . TYR A 1 21 ? 36.553 -17.183 3.549 1.00 27.77 ? 21 TYR A CD2 1 ATOM 141 C CE1 . TYR A 1 21 ? 37.612 -14.891 4.697 1.00 26.89 ? 21 TYR A CE1 1 ATOM 142 C CE2 . TYR A 1 21 ? 37.943 -17.076 3.753 1.00 28.22 ? 21 TYR A CE2 1 ATOM 143 C CZ . TYR A 1 21 ? 38.456 -15.920 4.331 1.00 28.28 ? 21 TYR A CZ 1 ATOM 144 O OH . TYR A 1 21 ? 39.816 -15.776 4.547 1.00 29.18 ? 21 TYR A OH 1 ATOM 145 N N . GLY A 1 22 ? 33.020 -19.183 3.784 1.00 23.26 ? 22 GLY A N 1 ATOM 146 C CA . GLY A 1 22 ? 33.243 -20.574 3.411 1.00 24.30 ? 22 GLY A CA 1 ATOM 147 C C . GLY A 1 22 ? 33.149 -20.805 1.904 1.00 27.62 ? 22 GLY A C 1 ATOM 148 O O . GLY A 1 22 ? 32.957 -19.867 1.123 1.00 28.86 ? 22 GLY A O 1 ATOM 149 N N . GLU A 1 23 ? 33.257 -22.063 1.491 1.00 28.13 ? 23 GLU A N 1 ATOM 150 C CA . GLU A 1 23 ? 33.319 -22.413 0.071 1.00 31.14 ? 23 GLU A CA 1 ATOM 151 C C . GLU A 1 23 ? 31.959 -22.778 -0.549 1.00 28.53 ? 23 GLU A C 1 ATOM 152 O O . GLU A 1 23 ? 31.203 -23.541 0.035 1.00 29.97 ? 23 GLU A O 1 ATOM 153 C CB . GLU A 1 23 ? 34.312 -23.569 -0.110 1.00 33.60 ? 23 GLU A CB 1 ATOM 154 C CG . GLU A 1 23 ? 34.302 -24.244 -1.479 1.00 35.94 ? 23 GLU A CG 1 ATOM 155 C CD . GLU A 1 23 ? 35.426 -25.254 -1.650 1.00 36.60 ? 23 GLU A CD 1 ATOM 156 O OE1 . GLU A 1 23 ? 36.611 -24.894 -1.413 1.00 39.25 ? 23 GLU A OE1 1 ATOM 157 O OE2 . GLU A 1 23 ? 35.126 -26.403 -2.045 1.00 37.12 ? 23 GLU A OE2 1 ATOM 158 N N . ILE A 1 24 ? 31.648 -22.216 -1.715 1.00 25.13 ? 24 ILE A N 1 ATOM 159 C CA . ILE A 1 24 ? 30.624 -22.795 -2.599 1.00 24.42 ? 24 ILE A CA 1 ATOM 160 C C . ILE A 1 24 ? 31.225 -23.167 -3.961 1.00 26.08 ? 24 ILE A C 1 ATOM 161 O O . ILE A 1 24 ? 32.325 -22.709 -4.303 1.00 26.17 ? 24 ILE A O 1 ATOM 162 C CB . ILE A 1 24 ? 29.373 -21.888 -2.802 1.00 24.20 ? 24 ILE A CB 1 ATOM 163 C CG1 . ILE A 1 24 ? 29.722 -20.565 -3.488 1.00 23.86 ? 24 ILE A CG1 1 ATOM 164 C CG2 . ILE A 1 24 ? 28.613 -21.669 -1.477 1.00 25.23 ? 24 ILE A CG2 1 ATOM 165 C CD1 . ILE A 1 24 ? 28.474 -19.861 -4.151 1.00 22.54 ? 24 ILE A CD1 1 ATOM 166 N N . GLY A 1 25 ? 30.513 -23.997 -4.727 1.00 26.34 ? 25 GLY A N 1 ATOM 167 C CA . GLY A 1 25 ? 30.921 -24.331 -6.098 1.00 26.36 ? 25 GLY A CA 1 ATOM 168 C C . GLY A 1 25 ? 29.860 -23.901 -7.093 1.00 28.17 ? 25 GLY A C 1 ATOM 169 O O . GLY A 1 25 ? 28.664 -24.139 -6.881 1.00 30.96 ? 25 GLY A O 1 ATOM 170 N N . ILE A 1 26 ? 30.277 -23.240 -8.166 1.00 26.84 ? 26 ILE A N 1 ATOM 171 C CA . ILE A 1 26 ? 29.334 -22.846 -9.215 1.00 28.06 ? 26 ILE A CA 1 ATOM 172 C C . ILE A 1 26 ? 29.727 -23.472 -10.555 1.00 29.24 ? 26 ILE A C 1 ATOM 173 O O . ILE A 1 26 ? 30.879 -23.334 -10.996 1.00 28.09 ? 26 ILE A O 1 ATOM 174 C CB . ILE A 1 26 ? 29.244 -21.313 -9.374 1.00 28.11 ? 26 ILE A CB 1 ATOM 175 C CG1 . ILE A 1 26 ? 29.107 -20.617 -8.010 1.00 27.29 ? 26 ILE A CG1 1 ATOM 176 C CG2 . ILE A 1 26 ? 28.099 -20.947 -10.308 1.00 30.14 ? 26 ILE A CG2 1 ATOM 177 C CD1 . ILE A 1 26 ? 28.820 -19.137 -8.096 1.00 26.98 ? 26 ILE A CD1 1 ATOM 178 N N . GLY A 1 27 ? 28.779 -24.172 -11.183 1.00 28.16 ? 27 GLY A N 1 ATOM 179 C CA . GLY A 1 27 ? 28.980 -24.677 -12.537 1.00 28.98 ? 27 GLY A CA 1 ATOM 180 C C . GLY A 1 27 ? 29.339 -26.146 -12.645 1.00 30.85 ? 27 GLY A C 1 ATOM 181 O O . GLY A 1 27 ? 29.378 -26.860 -11.634 1.00 32.48 ? 27 GLY A O 1 ATOM 182 N N . THR A 1 28 ? 29.583 -26.595 -13.880 1.00 29.75 ? 28 THR A N 1 ATOM 183 C CA . THR A 1 28 ? 29.995 -27.973 -14.165 1.00 29.42 ? 28 THR A CA 1 ATOM 184 C C . THR A 1 28 ? 31.180 -27.964 -15.122 1.00 29.96 ? 28 THR A C 1 ATOM 185 O O . THR A 1 28 ? 31.026 -27.558 -16.269 1.00 31.41 ? 28 THR A O 1 ATOM 186 C CB . THR A 1 28 ? 28.856 -28.821 -14.803 1.00 28.70 ? 28 THR A CB 1 ATOM 187 O OG1 . THR A 1 28 ? 27.658 -28.705 -14.023 1.00 27.57 ? 28 THR A OG1 1 ATOM 188 C CG2 . THR A 1 28 ? 29.257 -30.288 -14.882 1.00 26.98 ? 28 THR A CG2 1 ATOM 189 N N . PRO A 1 29 ? 32.372 -28.382 -14.653 1.00 29.19 ? 29 PRO A N 1 ATOM 190 C CA . PRO A 1 29 ? 32.705 -28.737 -13.274 1.00 29.47 ? 29 PRO A CA 1 ATOM 191 C C . PRO A 1 29 ? 32.670 -27.510 -12.329 1.00 28.17 ? 29 PRO A C 1 ATOM 192 O O . PRO A 1 29 ? 32.696 -26.373 -12.797 1.00 26.56 ? 29 PRO A O 1 ATOM 193 C CB . PRO A 1 29 ? 34.137 -29.303 -13.397 1.00 29.50 ? 29 PRO A CB 1 ATOM 194 C CG . PRO A 1 29 ? 34.707 -28.623 -14.574 1.00 29.43 ? 29 PRO A CG 1 ATOM 195 C CD . PRO A 1 29 ? 33.539 -28.534 -15.542 1.00 29.45 ? 29 PRO A CD 1 ATOM 196 N N . PRO A 1 30 ? 32.594 -27.746 -11.012 1.00 27.66 ? 30 PRO A N 1 ATOM 197 C CA . PRO A 1 30 ? 32.490 -26.666 -10.023 1.00 28.49 ? 30 PRO A CA 1 ATOM 198 C C . PRO A 1 30 ? 33.670 -25.688 -10.006 1.00 28.30 ? 30 PRO A C 1 ATOM 199 O O . PRO A 1 30 ? 34.822 -26.104 -9.879 1.00 29.61 ? 30 PRO A O 1 ATOM 200 C CB . PRO A 1 30 ? 32.401 -27.420 -8.681 1.00 26.14 ? 30 PRO A CB 1 ATOM 201 C CG . PRO A 1 30 ? 31.944 -28.784 -9.031 1.00 26.58 ? 30 PRO A CG 1 ATOM 202 C CD . PRO A 1 30 ? 32.562 -29.074 -10.370 1.00 27.92 ? 30 PRO A CD 1 ATOM 203 N N . GLN A 1 31 ? 33.362 -24.401 -10.152 1.00 27.83 ? 31 GLN A N 1 ATOM 204 C CA . GLN A 1 31 ? 34.319 -23.328 -9.914 1.00 26.26 ? 31 GLN A CA 1 ATOM 205 C C . GLN A 1 31 ? 34.041 -22.890 -8.492 1.00 27.29 ? 31 GLN A C 1 ATOM 206 O O . GLN A 1 31 ? 32.920 -22.471 -8.178 1.00 28.83 ? 31 GLN A O 1 ATOM 207 C CB . GLN A 1 31 ? 34.121 -22.157 -10.892 1.00 25.42 ? 31 GLN A CB 1 ATOM 208 C CG . GLN A 1 31 ? 34.467 -22.463 -12.359 1.00 25.59 ? 31 GLN A CG 1 ATOM 209 C CD . GLN A 1 31 ? 33.970 -21.402 -13.349 1.00 25.30 ? 31 GLN A CD 1 ATOM 210 O OE1 . GLN A 1 31 ? 34.215 -20.199 -13.183 1.00 25.49 ? 31 GLN A OE1 1 ATOM 211 N NE2 . GLN A 1 31 ? 33.281 -21.852 -14.393 1.00 24.01 ? 31 GLN A NE2 1 ATOM 212 N N . THR A 1 32 ? 35.045 -23.015 -7.626 1.00 27.49 ? 32 THR A N 1 ATOM 213 C CA . THR A 1 32 ? 34.875 -22.718 -6.207 1.00 27.12 ? 32 THR A CA 1 ATOM 214 C C . THR A 1 32 ? 35.146 -21.255 -5.879 1.00 24.75 ? 32 THR A C 1 ATOM 215 O O . THR A 1 32 ? 36.002 -20.619 -6.502 1.00 26.08 ? 32 THR A O 1 ATOM 216 C CB . THR A 1 32 ? 35.757 -23.602 -5.332 1.00 29.03 ? 32 THR A CB 1 ATOM 217 O OG1 . THR A 1 32 ? 37.135 -23.293 -5.588 1.00 32.24 ? 32 THR A OG1 1 ATOM 218 C CG2 . THR A 1 32 ? 35.485 -25.078 -5.619 1.00 26.53 ? 32 THR A CG2 1 ATOM 219 N N . PHE A 1 33 ? 34.378 -20.733 -4.923 1.00 21.14 ? 33 PHE A N 1 ATOM 220 C CA . PHE A 1 33 ? 34.442 -19.338 -4.482 1.00 22.23 ? 33 PHE A CA 1 ATOM 221 C C . PHE A 1 33 ? 34.294 -19.297 -2.982 1.00 21.58 ? 33 PHE A C 1 ATOM 222 O O . PHE A 1 33 ? 33.515 -20.070 -2.422 1.00 20.92 ? 33 PHE A O 1 ATOM 223 C CB . PHE A 1 33 ? 33.303 -18.508 -5.098 1.00 22.25 ? 33 PHE A CB 1 ATOM 224 C CG . PHE A 1 33 ? 33.397 -18.384 -6.575 1.00 23.74 ? 33 PHE A CG 1 ATOM 225 C CD1 . PHE A 1 33 ? 34.014 -17.281 -7.148 1.00 23.21 ? 33 PHE A CD1 1 ATOM 226 C CD2 . PHE A 1 33 ? 32.904 -19.389 -7.401 1.00 23.74 ? 33 PHE A CD2 1 ATOM 227 C CE1 . PHE A 1 33 ? 34.131 -17.170 -8.520 1.00 24.81 ? 33 PHE A CE1 1 ATOM 228 C CE2 . PHE A 1 33 ? 33.025 -19.290 -8.778 1.00 24.86 ? 33 PHE A CE2 1 ATOM 229 C CZ . PHE A 1 33 ? 33.640 -18.173 -9.340 1.00 24.20 ? 33 PHE A CZ 1 ATOM 230 N N . LYS A 1 34 ? 35.031 -18.391 -2.341 1.00 22.72 ? 34 LYS A N 1 ATOM 231 C CA . LYS A 1 34 ? 34.813 -18.071 -0.917 1.00 22.58 ? 34 LYS A CA 1 ATOM 232 C C . LYS A 1 34 ? 33.727 -17.012 -0.792 1.00 21.76 ? 34 LYS A C 1 ATOM 233 O O . LYS A 1 34 ? 33.764 -15.972 -1.460 1.00 21.47 ? 34 LYS A O 1 ATOM 234 C CB . LYS A 1 34 ? 36.085 -17.549 -0.270 1.00 25.27 ? 34 LYS A CB 1 ATOM 235 C CG . LYS A 1 34 ? 37.303 -18.426 -0.456 1.00 28.35 ? 34 LYS A CG 1 ATOM 236 C CD . LYS A 1 34 ? 38.400 -17.959 0.471 1.00 31.97 ? 34 LYS A CD 1 ATOM 237 C CE . LYS A 1 34 ? 39.752 -18.552 0.138 1.00 35.41 ? 34 LYS A CE 1 ATOM 238 N NZ . LYS A 1 34 ? 40.424 -17.743 -0.920 1.00 37.14 ? 34 LYS A NZ 1 ATOM 239 N N . VAL A 1 35 ? 32.751 -17.280 0.060 1.00 22.45 ? 35 VAL A N 1 ATOM 240 C CA . VAL A 1 35 ? 31.615 -16.397 0.203 1.00 22.03 ? 35 VAL A CA 1 ATOM 241 C C . VAL A 1 35 ? 31.190 -16.181 1.650 1.00 23.42 ? 35 VAL A C 1 ATOM 242 O O . VAL A 1 35 ? 31.246 -17.100 2.476 1.00 25.01 ? 35 VAL A O 1 ATOM 243 C CB . VAL A 1 35 ? 30.399 -16.904 -0.614 1.00 22.61 ? 35 VAL A CB 1 ATOM 244 C CG1 . VAL A 1 35 ? 30.673 -16.800 -2.120 1.00 20.46 ? 35 VAL A CG1 1 ATOM 245 C CG2 . VAL A 1 35 ? 29.982 -18.328 -0.181 1.00 19.61 ? 35 VAL A CG2 1 ATOM 246 N N . VAL A 1 36 ? 30.778 -14.950 1.940 1.00 22.98 ? 36 VAL A N 1 ATOM 247 C CA . VAL A 1 36 ? 30.120 -14.595 3.195 1.00 22.42 ? 36 VAL A CA 1 ATOM 248 C C . VAL A 1 36 ? 28.658 -14.985 3.015 1.00 23.06 ? 36 VAL A C 1 ATOM 249 O O . VAL A 1 36 ? 28.056 -14.675 1.978 1.00 22.41 ? 36 VAL A O 1 ATOM 250 C CB . VAL A 1 36 ? 30.247 -13.064 3.512 1.00 21.53 ? 36 VAL A CB 1 ATOM 251 C CG1 . VAL A 1 36 ? 29.269 -12.630 4.594 1.00 22.07 ? 36 VAL A CG1 1 ATOM 252 C CG2 . VAL A 1 36 ? 31.663 -12.703 3.932 1.00 17.40 ? 36 VAL A CG2 1 ATOM 253 N N . PHE A 1 37 ? 28.111 -15.691 4.009 1.00 22.57 ? 37 PHE A N 1 ATOM 254 C CA . PHE A 1 37 ? 26.689 -16.029 4.039 1.00 22.02 ? 37 PHE A CA 1 ATOM 255 C C . PHE A 1 37 ? 25.967 -14.950 4.852 1.00 23.20 ? 37 PHE A C 1 ATOM 256 O O . PHE A 1 37 ? 26.128 -14.860 6.075 1.00 22.75 ? 37 PHE A O 1 ATOM 257 C CB . PHE A 1 37 ? 26.480 -17.432 4.591 1.00 20.32 ? 37 PHE A CB 1 ATOM 258 C CG . PHE A 1 37 ? 27.138 -18.525 3.749 1.00 21.65 ? 37 PHE A CG 1 ATOM 259 C CD1 . PHE A 1 37 ? 28.469 -18.897 3.971 1.00 20.54 ? 37 PHE A CD1 1 ATOM 260 C CD2 . PHE A 1 37 ? 26.419 -19.183 2.751 1.00 20.06 ? 37 PHE A CD2 1 ATOM 261 C CE1 . PHE A 1 37 ? 29.075 -19.903 3.206 1.00 22.04 ? 37 PHE A CE1 1 ATOM 262 C CE2 . PHE A 1 37 ? 27.013 -20.181 1.977 1.00 20.92 ? 37 PHE A CE2 1 ATOM 263 C CZ . PHE A 1 37 ? 28.346 -20.550 2.209 1.00 20.48 ? 37 PHE A CZ 1 ATOM 264 N N . ASP A 1 38 ? 25.217 -14.111 4.136 1.00 22.94 ? 38 ASP A N 1 ATOM 265 C CA . ASP A 1 38 ? 24.786 -12.806 4.619 1.00 25.29 ? 38 ASP A CA 1 ATOM 266 C C . ASP A 1 38 ? 23.261 -12.681 4.830 1.00 25.29 ? 38 ASP A C 1 ATOM 267 O O . ASP A 1 38 ? 22.512 -12.488 3.880 1.00 24.09 ? 38 ASP A O 1 ATOM 268 C CB . ASP A 1 38 ? 25.262 -11.726 3.631 1.00 25.99 ? 38 ASP A CB 1 ATOM 269 C CG . ASP A 1 38 ? 24.917 -10.301 4.083 1.00 28.63 ? 38 ASP A CG 1 ATOM 270 O OD1 . ASP A 1 38 ? 24.614 -10.109 5.279 1.00 31.04 ? 38 ASP A OD1 1 ATOM 271 O OD2 . ASP A 1 38 ? 24.948 -9.364 3.246 1.00 29.10 ? 38 ASP A OD2 1 ATOM 272 N N . THR A 1 39 ? 22.810 -12.729 6.078 1.00 25.09 ? 39 THR A N 1 ATOM 273 C CA . THR A 1 39 ? 21.373 -12.554 6.360 1.00 26.20 ? 39 THR A CA 1 ATOM 274 C C . THR A 1 39 ? 20.868 -11.111 6.118 1.00 26.87 ? 39 THR A C 1 ATOM 275 O O . THR A 1 39 ? 19.665 -10.835 6.177 1.00 24.80 ? 39 THR A O 1 ATOM 276 C CB . THR A 1 39 ? 21.007 -13.042 7.764 1.00 26.10 ? 39 THR A CB 1 ATOM 277 O OG1 . THR A 1 39 ? 21.766 -12.313 8.730 1.00 28.23 ? 39 THR A OG1 1 ATOM 278 C CG2 . THR A 1 39 ? 21.314 -14.539 7.905 1.00 25.48 ? 39 THR A CG2 1 ATOM 279 N N . GLY A 1 40 ? 21.789 -10.200 5.813 1.00 26.48 ? 40 GLY A N 1 ATOM 280 C CA . GLY A 1 40 ? 21.410 -8.823 5.529 1.00 26.59 ? 40 GLY A CA 1 ATOM 281 C C . GLY A 1 40 ? 21.243 -8.495 4.057 1.00 28.97 ? 40 GLY A C 1 ATOM 282 O O . GLY A 1 40 ? 21.031 -7.337 3.716 1.00 29.66 ? 40 GLY A O 1 ATOM 283 N N . SER A 1 41 ? 21.377 -9.508 3.190 1.00 30.25 ? 41 SER A N 1 ATOM 284 C CA . SER A 1 41 ? 21.120 -9.390 1.759 1.00 29.11 ? 41 SER A CA 1 ATOM 285 C C . SER A 1 41 ? 20.469 -10.681 1.237 1.00 30.32 ? 41 SER A C 1 ATOM 286 O O . SER A 1 41 ? 20.450 -11.696 1.938 1.00 29.70 ? 41 SER A O 1 ATOM 287 C CB . SER A 1 41 ? 22.405 -9.045 0.995 1.00 30.72 ? 41 SER A CB 1 ATOM 288 O OG . SER A 1 41 ? 23.424 -10.036 1.181 1.00 31.82 ? 41 SER A OG 1 ATOM 289 N N . SER A 1 42 ? 19.913 -10.637 0.021 1.00 31.63 ? 42 SER A N 1 ATOM 290 C CA . SER A 1 42 ? 19.127 -11.762 -0.515 1.00 31.60 ? 42 SER A CA 1 ATOM 291 C C . SER A 1 42 ? 19.633 -12.300 -1.853 1.00 31.35 ? 42 SER A C 1 ATOM 292 O O . SER A 1 42 ? 19.068 -13.242 -2.383 1.00 32.19 ? 42 SER A O 1 ATOM 293 C CB . SER A 1 42 ? 17.654 -11.367 -0.675 1.00 32.59 ? 42 SER A CB 1 ATOM 294 O OG . SER A 1 42 ? 17.142 -10.759 0.491 1.00 35.04 ? 42 SER A OG 1 ATOM 295 N N . ASN A 1 43 ? 20.681 -11.700 -2.407 1.00 31.16 ? 43 ASN A N 1 ATOM 296 C CA . ASN A 1 43 ? 21.220 -12.156 -3.689 1.00 29.95 ? 43 ASN A CA 1 ATOM 297 C C . ASN A 1 43 ? 22.501 -12.959 -3.583 1.00 29.95 ? 43 ASN A C 1 ATOM 298 O O . ASN A 1 43 ? 23.269 -12.773 -2.632 1.00 30.85 ? 43 ASN A O 1 ATOM 299 C CB . ASN A 1 43 ? 21.465 -10.964 -4.605 1.00 30.10 ? 43 ASN A CB 1 ATOM 300 C CG . ASN A 1 43 ? 20.187 -10.337 -5.087 1.00 29.76 ? 43 ASN A CG 1 ATOM 301 O OD1 . ASN A 1 43 ? 19.528 -9.610 -4.352 1.00 31.23 ? 43 ASN A OD1 1 ATOM 302 N ND2 . ASN A 1 43 ? 19.831 -10.607 -6.333 1.00 28.27 ? 43 ASN A ND2 1 ATOM 303 N N . VAL A 1 44 ? 22.725 -13.845 -4.564 1.00 29.01 ? 44 VAL A N 1 ATOM 304 C CA . VAL A 1 44 ? 24.039 -14.454 -4.794 1.00 28.91 ? 44 VAL A CA 1 ATOM 305 C C . VAL A 1 44 ? 24.804 -13.594 -5.819 1.00 29.24 ? 44 VAL A C 1 ATOM 306 O O . VAL A 1 44 ? 24.292 -13.289 -6.897 1.00 27.64 ? 44 VAL A O 1 ATOM 307 C CB . VAL A 1 44 ? 23.945 -15.929 -5.301 1.00 29.84 ? 44 VAL A CB 1 ATOM 308 C CG1 . VAL A 1 44 ? 25.349 -16.542 -5.455 1.00 28.97 ? 44 VAL A CG1 1 ATOM 309 C CG2 . VAL A 1 44 ? 23.105 -16.796 -4.368 1.00 28.13 ? 44 VAL A CG2 1 ATOM 310 N N . TRP A 1 45 ? 26.015 -13.183 -5.450 1.00 31.00 ? 45 TRP A N 1 ATOM 311 C CA . TRP A 1 45 ? 26.899 -12.390 -6.304 1.00 30.08 ? 45 TRP A CA 1 ATOM 312 C C . TRP A 1 45 ? 28.277 -13.008 -6.282 1.00 29.82 ? 45 TRP A C 1 ATOM 313 O O . TRP A 1 45 ? 28.773 -13.370 -5.210 1.00 29.11 ? 45 TRP A O 1 ATOM 314 C CB . TRP A 1 45 ? 27.087 -10.978 -5.762 1.00 33.57 ? 45 TRP A CB 1 ATOM 315 C CG . TRP A 1 45 ? 25.893 -10.113 -5.610 1.00 34.35 ? 45 TRP A CG 1 ATOM 316 C CD1 . TRP A 1 45 ? 25.096 -10.010 -4.504 1.00 35.78 ? 45 TRP A CD1 1 ATOM 317 C CD2 . TRP A 1 45 ? 25.399 -9.149 -6.555 1.00 35.47 ? 45 TRP A CD2 1 ATOM 318 N NE1 . TRP A 1 45 ? 24.115 -9.062 -4.714 1.00 36.85 ? 45 TRP A NE1 1 ATOM 319 C CE2 . TRP A 1 45 ? 24.275 -8.520 -5.963 1.00 35.88 ? 45 TRP A CE2 1 ATOM 320 C CE3 . TRP A 1 45 ? 25.786 -8.763 -7.848 1.00 35.52 ? 45 TRP A CE3 1 ATOM 321 C CZ2 . TRP A 1 45 ? 23.532 -7.525 -6.621 1.00 34.64 ? 45 TRP A CZ2 1 ATOM 322 C CZ3 . TRP A 1 45 ? 25.041 -7.771 -8.505 1.00 35.66 ? 45 TRP A CZ3 1 ATOM 323 C CH2 . TRP A 1 45 ? 23.931 -7.163 -7.884 1.00 34.73 ? 45 TRP A CH2 1 ATOM 324 N N . VAL A 1 46 ? 28.896 -13.117 -7.459 1.00 29.34 ? 46 VAL A N 1 ATOM 325 C CA . VAL A 1 46 ? 30.320 -13.462 -7.590 1.00 27.85 ? 46 VAL A CA 1 ATOM 326 C C . VAL A 1 46 ? 30.908 -12.624 -8.722 1.00 28.89 ? 46 VAL A C 1 ATOM 327 O O . VAL A 1 46 ? 30.178 -12.253 -9.654 1.00 31.33 ? 46 VAL A O 1 ATOM 328 C CB . VAL A 1 46 ? 30.560 -14.962 -7.889 1.00 27.42 ? 46 VAL A CB 1 ATOM 329 C CG1 . VAL A 1 46 ? 30.108 -15.832 -6.717 1.00 25.83 ? 46 VAL A CG1 1 ATOM 330 C CG2 . VAL A 1 46 ? 29.867 -15.398 -9.208 1.00 26.62 ? 46 VAL A CG2 1 ATOM 331 N N . PRO A 1 47 ? 32.222 -12.328 -8.669 1.00 27.02 ? 47 PRO A N 1 ATOM 332 C CA . PRO A 1 47 ? 32.791 -11.590 -9.808 1.00 25.97 ? 47 PRO A CA 1 ATOM 333 C C . PRO A 1 47 ? 32.735 -12.416 -11.096 1.00 27.48 ? 47 PRO A C 1 ATOM 334 O O . PRO A 1 47 ? 32.780 -13.649 -11.052 1.00 27.92 ? 47 PRO A O 1 ATOM 335 C CB . PRO A 1 47 ? 34.238 -11.327 -9.393 1.00 25.48 ? 47 PRO A CB 1 ATOM 336 C CG . PRO A 1 47 ? 34.361 -11.753 -7.953 1.00 25.27 ? 47 PRO A CG 1 ATOM 337 C CD . PRO A 1 47 ? 33.222 -12.653 -7.636 1.00 24.81 ? 47 PRO A CD 1 ATOM 338 N N . SER A 1 48 ? 32.625 -11.726 -12.230 1.00 28.71 ? 48 SER A N 1 ATOM 339 C CA . SER A 1 48 ? 32.461 -12.344 -13.536 1.00 28.30 ? 48 SER A CA 1 ATOM 340 C C . SER A 1 48 ? 33.795 -12.291 -14.241 1.00 30.98 ? 48 SER A C 1 ATOM 341 O O . SER A 1 48 ? 34.548 -11.342 -14.033 1.00 32.95 ? 48 SER A O 1 ATOM 342 C CB . SER A 1 48 ? 31.444 -11.541 -14.350 1.00 29.28 ? 48 SER A CB 1 ATOM 343 O OG . SER A 1 48 ? 31.413 -11.930 -15.710 1.00 27.63 ? 48 SER A OG 1 ATOM 344 N N . SER A 1 49 ? 34.083 -13.290 -15.082 1.00 30.09 ? 49 SER A N 1 ATOM 345 C CA . SER A 1 49 ? 35.283 -13.266 -15.921 1.00 32.01 ? 49 SER A CA 1 ATOM 346 C C . SER A 1 49 ? 35.258 -12.056 -16.849 1.00 34.20 ? 49 SER A C 1 ATOM 347 O O . SER A 1 49 ? 36.275 -11.719 -17.474 1.00 33.73 ? 49 SER A O 1 ATOM 348 C CB . SER A 1 49 ? 35.407 -14.538 -16.746 1.00 31.55 ? 49 SER A CB 1 ATOM 349 O OG . SER A 1 49 ? 34.321 -14.651 -17.643 1.00 32.74 ? 49 SER A OG 1 ATOM 350 N N . LYS A 1 50 ? 34.088 -11.417 -16.925 1.00 35.68 ? 50 LYS A N 1 ATOM 351 C CA . LYS A 1 50 ? 33.880 -10.214 -17.732 1.00 37.77 ? 50 LYS A CA 1 ATOM 352 C C . LYS A 1 50 ? 34.170 -8.929 -16.950 1.00 39.39 ? 50 LYS A C 1 ATOM 353 O O . LYS A 1 50 ? 33.964 -7.833 -17.474 1.00 41.81 ? 50 LYS A O 1 ATOM 354 C CB . LYS A 1 50 ? 32.454 -10.164 -18.286 1.00 37.71 ? 50 LYS A CB 1 ATOM 355 C CG . LYS A 1 50 ? 32.179 -11.096 -19.455 1.00 40.45 ? 50 LYS A CG 1 ATOM 356 C CD . LYS A 1 50 ? 31.582 -12.420 -19.001 1.00 42.01 ? 50 LYS A CD 1 ATOM 357 C CE . LYS A 1 50 ? 30.940 -13.158 -20.155 1.00 44.47 ? 50 LYS A CE 1 ATOM 358 N NZ . LYS A 1 50 ? 30.724 -14.612 -19.843 1.00 46.27 ? 50 LYS A NZ 1 ATOM 359 N N . CYS A 1 51 ? 34.628 -9.054 -15.706 1.00 38.43 ? 51 CYS A N 1 ATOM 360 C CA . CYS A 1 51 ? 35.064 -7.884 -14.961 1.00 38.20 ? 51 CYS A CA 1 ATOM 361 C C . CYS A 1 51 ? 36.482 -7.521 -15.371 1.00 38.61 ? 51 CYS A C 1 ATOM 362 O O . CYS A 1 51 ? 37.418 -8.304 -15.191 1.00 39.28 ? 51 CYS A O 1 ATOM 363 C CB . CYS A 1 51 ? 35.000 -8.114 -13.454 1.00 39.63 ? 51 CYS A CB 1 ATOM 364 S SG . CYS A 1 51 ? 35.295 -6.610 -12.482 1.00 41.73 ? 51 CYS A SG 1 ATOM 365 N N . SER A 1 52 ? 36.630 -6.328 -15.927 1.00 38.49 ? 52 SER A N 1 ATOM 366 C CA . SER A 1 52 ? 37.923 -5.824 -16.352 1.00 38.93 ? 52 SER A CA 1 ATOM 367 C C . SER A 1 52 ? 38.956 -5.868 -15.229 1.00 40.31 ? 52 SER A C 1 ATOM 368 O O . SER A 1 52 ? 38.636 -5.632 -14.058 1.00 41.42 ? 52 SER A O 1 ATOM 369 C CB . SER A 1 52 ? 37.777 -4.394 -16.871 1.00 38.52 ? 52 SER A CB 1 ATOM 370 O OG . SER A 1 52 ? 39.041 -3.831 -17.143 1.00 38.58 ? 52 SER A OG 1 ATOM 371 N N . ARG A 1 53 ? 40.197 -6.164 -15.601 1.00 40.79 ? 53 ARG A N 1 ATOM 372 C CA . ARG A 1 53 ? 41.316 -6.178 -14.660 1.00 42.00 ? 53 ARG A CA 1 ATOM 373 C C . ARG A 1 53 ? 41.680 -4.754 -14.211 1.00 42.39 ? 53 ARG A C 1 ATOM 374 O O . ARG A 1 53 ? 42.491 -4.566 -13.297 1.00 42.18 ? 53 ARG A O 1 ATOM 375 C CB . ARG A 1 53 ? 42.532 -6.892 -15.274 1.00 43.83 ? 53 ARG A CB 1 ATOM 376 C CG . ARG A 1 53 ? 42.894 -6.405 -16.672 1.00 45.09 ? 53 ARG A CG 1 ATOM 377 C CD . ARG A 1 53 ? 44.347 -6.636 -17.018 1.00 46.80 ? 53 ARG A CD 1 ATOM 378 N NE . ARG A 1 53 ? 44.808 -5.601 -17.941 1.00 48.18 ? 53 ARG A NE 1 ATOM 379 C CZ . ARG A 1 53 ? 45.525 -4.538 -17.583 1.00 48.34 ? 53 ARG A CZ 1 ATOM 380 N NH1 . ARG A 1 53 ? 45.885 -4.379 -16.314 1.00 48.33 ? 53 ARG A NH1 1 ATOM 381 N NH2 . ARG A 1 53 ? 45.891 -3.636 -18.495 1.00 47.07 ? 53 ARG A NH2 1 ATOM 382 N N . LEU A 1 54 ? 41.071 -3.761 -14.860 1.00 42.49 ? 54 LEU A N 1 ATOM 383 C CA . LEU A 1 54 ? 41.184 -2.362 -14.447 1.00 41.78 ? 54 LEU A CA 1 ATOM 384 C C . LEU A 1 54 ? 40.270 -2.017 -13.264 1.00 41.43 ? 54 LEU A C 1 ATOM 385 O O . LEU A 1 54 ? 40.227 -0.871 -12.806 1.00 41.15 ? 54 LEU A O 1 ATOM 386 C CB . LEU A 1 54 ? 40.931 -1.426 -15.633 1.00 42.77 ? 54 LEU A CB 1 ATOM 387 C CG . LEU A 1 54 ? 42.187 -1.179 -16.473 1.00 44.78 ? 54 LEU A CG 1 ATOM 388 C CD1 . LEU A 1 54 ? 42.225 -2.109 -17.702 1.00 43.55 ? 54 LEU A CD1 1 ATOM 389 C CD2 . LEU A 1 54 ? 42.293 0.292 -16.886 1.00 44.19 ? 54 LEU A CD2 1 ATOM 390 N N . TYR A 1 55 ? 39.526 -3.007 -12.777 1.00 41.81 ? 55 TYR A N 1 ATOM 391 C CA . TYR A 1 55 ? 38.879 -2.873 -11.475 1.00 41.85 ? 55 TYR A CA 1 ATOM 392 C C . TYR A 1 55 ? 39.677 -3.643 -10.453 1.00 42.62 ? 55 TYR A C 1 ATOM 393 O O . TYR A 1 55 ? 39.833 -4.862 -10.563 1.00 42.52 ? 55 TYR A O 1 ATOM 394 C CB . TYR A 1 55 ? 37.426 -3.334 -11.493 1.00 40.29 ? 55 TYR A CB 1 ATOM 395 C CG . TYR A 1 55 ? 36.556 -2.474 -12.360 1.00 40.19 ? 55 TYR A CG 1 ATOM 396 C CD1 . TYR A 1 55 ? 36.271 -1.159 -12.011 1.00 41.24 ? 55 TYR A CD1 1 ATOM 397 C CD2 . TYR A 1 55 ? 36.023 -2.969 -13.539 1.00 39.08 ? 55 TYR A CD2 1 ATOM 398 C CE1 . TYR A 1 55 ? 35.472 -0.360 -12.825 1.00 40.19 ? 55 TYR A CE1 1 ATOM 399 C CE2 . TYR A 1 55 ? 35.234 -2.189 -14.340 1.00 38.53 ? 55 TYR A CE2 1 ATOM 400 C CZ . TYR A 1 55 ? 34.965 -0.889 -13.983 1.00 39.26 ? 55 TYR A CZ 1 ATOM 401 O OH . TYR A 1 55 ? 34.165 -0.128 -14.800 1.00 41.52 ? 55 TYR A OH 1 ATOM 402 N N . THR A 1 56 ? 40.180 -2.909 -9.464 1.00 43.63 ? 56 THR A N 1 ATOM 403 C CA . THR A 1 56 ? 41.045 -3.455 -8.428 1.00 45.31 ? 56 THR A CA 1 ATOM 404 C C . THR A 1 56 ? 40.387 -4.619 -7.678 1.00 44.41 ? 56 THR A C 1 ATOM 405 O O . THR A 1 56 ? 41.026 -5.639 -7.422 1.00 45.06 ? 56 THR A O 1 ATOM 406 C CB . THR A 1 56 ? 41.468 -2.357 -7.431 1.00 46.86 ? 56 THR A CB 1 ATOM 407 O OG1 . THR A 1 56 ? 41.589 -1.102 -8.121 1.00 47.52 ? 56 THR A OG1 1 ATOM 408 C CG2 . THR A 1 56 ? 42.798 -2.720 -6.769 1.00 46.79 ? 56 THR A CG2 1 ATOM 409 N N . ALA A 1 57 ? 39.109 -4.466 -7.349 1.00 42.94 ? 57 ALA A N 1 ATOM 410 C CA . ALA A 1 57 ? 38.355 -5.508 -6.665 1.00 44.02 ? 57 ALA A CA 1 ATOM 411 C C . ALA A 1 57 ? 38.255 -6.824 -7.460 1.00 45.14 ? 57 ALA A C 1 ATOM 412 O O . ALA A 1 57 ? 38.045 -7.891 -6.883 1.00 47.50 ? 57 ALA A O 1 ATOM 413 C CB . ALA A 1 57 ? 36.967 -4.995 -6.297 1.00 42.61 ? 57 ALA A CB 1 ATOM 414 N N . CYS A 1 58 ? 38.407 -6.755 -8.777 1.00 44.46 ? 58 CYS A N 1 ATOM 415 C CA . CYS A 1 58 ? 38.297 -7.946 -9.598 1.00 44.83 ? 58 CYS A CA 1 ATOM 416 C C . CYS A 1 58 ? 39.622 -8.630 -9.860 1.00 45.59 ? 58 CYS A C 1 ATOM 417 O O . CYS A 1 58 ? 39.648 -9.813 -10.212 1.00 47.77 ? 58 CYS A O 1 ATOM 418 C CB . CYS A 1 58 ? 37.618 -7.619 -10.918 1.00 43.95 ? 58 CYS A CB 1 ATOM 419 S SG . CYS A 1 58 ? 35.880 -7.338 -10.703 1.00 46.66 ? 58 CYS A SG 1 ATOM 420 N N . VAL A 1 59 ? 40.713 -7.890 -9.694 1.00 44.39 ? 59 VAL A N 1 ATOM 421 C CA . VAL A 1 59 ? 42.036 -8.387 -10.067 1.00 45.37 ? 59 VAL A CA 1 ATOM 422 C C . VAL A 1 59 ? 42.654 -9.389 -9.061 1.00 45.11 ? 59 VAL A C 1 ATOM 423 O O . VAL A 1 59 ? 43.566 -10.130 -9.418 1.00 46.28 ? 59 VAL A O 1 ATOM 424 C CB . VAL A 1 59 ? 43.011 -7.214 -10.435 1.00 46.38 ? 59 VAL A CB 1 ATOM 425 C CG1 . VAL A 1 59 ? 43.289 -6.321 -9.229 1.00 46.92 ? 59 VAL A CG1 1 ATOM 426 C CG2 . VAL A 1 59 ? 44.310 -7.737 -11.035 1.00 47.54 ? 59 VAL A CG2 1 ATOM 427 N N . TYR A 1 60 ? 42.158 -9.434 -7.825 1.00 43.83 ? 60 TYR A N 1 ATOM 428 C CA . TYR A 1 60 ? 42.702 -10.386 -6.843 1.00 43.27 ? 60 TYR A CA 1 ATOM 429 C C . TYR A 1 60 ? 41.708 -11.437 -6.376 1.00 40.88 ? 60 TYR A C 1 ATOM 430 O O . TYR A 1 60 ? 41.975 -12.182 -5.439 1.00 41.06 ? 60 TYR A O 1 ATOM 431 C CB . TYR A 1 60 ? 43.341 -9.653 -5.655 1.00 47.11 ? 60 TYR A CB 1 ATOM 432 C CG . TYR A 1 60 ? 44.514 -8.823 -6.100 1.00 48.38 ? 60 TYR A CG 1 ATOM 433 C CD1 . TYR A 1 60 ? 44.540 -7.447 -5.912 1.00 48.53 ? 60 TYR A CD1 1 ATOM 434 C CD2 . TYR A 1 60 ? 45.574 -9.419 -6.776 1.00 48.66 ? 60 TYR A CD2 1 ATOM 435 C CE1 . TYR A 1 60 ? 45.618 -6.690 -6.360 1.00 49.87 ? 60 TYR A CE1 1 ATOM 436 C CE2 . TYR A 1 60 ? 46.635 -8.683 -7.231 1.00 49.24 ? 60 TYR A CE2 1 ATOM 437 C CZ . TYR A 1 60 ? 46.667 -7.324 -7.021 1.00 49.28 ? 60 TYR A CZ 1 ATOM 438 O OH . TYR A 1 60 ? 47.757 -6.616 -7.486 1.00 49.58 ? 60 TYR A OH 1 ATOM 439 N N . HIS A 1 61 ? 40.567 -11.499 -7.049 1.00 37.92 ? 61 HIS A N 1 ATOM 440 C CA . HIS A 1 61 ? 39.528 -12.442 -6.707 1.00 34.45 ? 61 HIS A CA 1 ATOM 441 C C . HIS A 1 61 ? 39.268 -13.409 -7.841 1.00 34.65 ? 61 HIS A C 1 ATOM 442 O O . HIS A 1 61 ? 39.614 -13.149 -9.004 1.00 34.41 ? 61 HIS A O 1 ATOM 443 C CB . HIS A 1 61 ? 38.246 -11.706 -6.328 1.00 33.43 ? 61 HIS A CB 1 ATOM 444 C CG . HIS A 1 61 ? 38.345 -10.975 -5.026 1.00 32.58 ? 61 HIS A CG 1 ATOM 445 N ND1 . HIS A 1 61 ? 38.028 -9.641 -4.894 1.00 32.16 ? 61 HIS A ND1 1 ATOM 446 C CD2 . HIS A 1 61 ? 38.753 -11.389 -3.802 1.00 30.30 ? 61 HIS A CD2 1 ATOM 447 C CE1 . HIS A 1 61 ? 38.235 -9.265 -3.644 1.00 31.39 ? 61 HIS A CE1 1 ATOM 448 N NE2 . HIS A 1 61 ? 38.672 -10.308 -2.961 1.00 30.36 ? 61 HIS A NE2 1 ATOM 449 N N . LYS A 1 62 ? 38.653 -14.527 -7.477 1.00 32.95 ? 62 LYS A N 1 ATOM 450 C CA . LYS A 1 62 ? 38.225 -15.539 -8.419 1.00 31.47 ? 62 LYS A CA 1 ATOM 451 C C . LYS A 1 62 ? 37.092 -15.003 -9.285 1.00 30.74 ? 62 LYS A C 1 ATOM 452 O O . LYS A 1 62 ? 36.168 -14.359 -8.782 1.00 31.61 ? 62 LYS A O 1 ATOM 453 C CB . LYS A 1 62 ? 37.764 -16.786 -7.657 1.00 32.10 ? 62 LYS A CB 1 ATOM 454 C CG . LYS A 1 62 ? 38.820 -17.378 -6.712 1.00 32.72 ? 62 LYS A CG 1 ATOM 455 C CD . LYS A 1 62 ? 40.121 -17.722 -7.449 1.00 36.11 ? 62 LYS A CD 1 ATOM 456 C CE . LYS A 1 62 ? 40.973 -18.748 -6.693 1.00 37.91 ? 62 LYS A CE 1 ATOM 457 N NZ . LYS A 1 62 ? 41.396 -18.263 -5.345 1.00 39.02 ? 62 LYS A NZ 1 ATOM 458 N N . LEU A 1 63 ? 37.161 -15.279 -10.582 1.00 28.75 ? 63 LEU A N 1 ATOM 459 C CA . LEU A 1 63 ? 36.152 -14.812 -11.517 1.00 27.95 ? 63 LEU A CA 1 ATOM 460 C C . LEU A 1 63 ? 35.377 -16.000 -12.070 1.00 28.28 ? 63 LEU A C 1 ATOM 461 O O . LEU A 1 63 ? 35.972 -16.994 -12.444 1.00 30.14 ? 63 LEU A O 1 ATOM 462 C CB . LEU A 1 63 ? 36.810 -14.004 -12.651 1.00 28.21 ? 63 LEU A CB 1 ATOM 463 C CG . LEU A 1 63 ? 37.763 -12.863 -12.256 1.00 26.99 ? 63 LEU A CG 1 ATOM 464 C CD1 . LEU A 1 63 ? 38.341 -12.173 -13.479 1.00 26.47 ? 63 LEU A CD1 1 ATOM 465 C CD2 . LEU A 1 63 ? 37.090 -11.842 -11.322 1.00 25.27 ? 63 LEU A CD2 1 ATOM 466 N N . PHE A 1 64 ? 34.049 -15.908 -12.107 1.00 28.25 ? 64 PHE A N 1 ATOM 467 C CA . PHE A 1 64 ? 33.253 -16.976 -12.678 1.00 26.18 ? 64 PHE A CA 1 ATOM 468 C C . PHE A 1 64 ? 33.357 -16.944 -14.191 1.00 28.52 ? 64 PHE A C 1 ATOM 469 O O . PHE A 1 64 ? 33.193 -15.882 -14.800 1.00 29.75 ? 64 PHE A O 1 ATOM 470 C CB . PHE A 1 64 ? 31.789 -16.864 -12.266 1.00 25.13 ? 64 PHE A CB 1 ATOM 471 C CG . PHE A 1 64 ? 30.924 -17.907 -12.890 1.00 22.84 ? 64 PHE A CG 1 ATOM 472 C CD1 . PHE A 1 64 ? 31.024 -19.233 -12.484 1.00 21.46 ? 64 PHE A CD1 1 ATOM 473 C CD2 . PHE A 1 64 ? 30.049 -17.577 -13.910 1.00 22.57 ? 64 PHE A CD2 1 ATOM 474 C CE1 . PHE A 1 64 ? 30.264 -20.207 -13.073 1.00 20.46 ? 64 PHE A CE1 1 ATOM 475 C CE2 . PHE A 1 64 ? 29.276 -18.545 -14.512 1.00 22.78 ? 64 PHE A CE2 1 ATOM 476 C CZ . PHE A 1 64 ? 29.383 -19.870 -14.085 1.00 23.56 ? 64 PHE A CZ 1 ATOM 477 N N . ASP A 1 65 ? 33.633 -18.098 -14.798 1.00 29.36 ? 65 ASP A N 1 ATOM 478 C CA . ASP A 1 65 ? 33.648 -18.184 -16.258 1.00 31.58 ? 65 ASP A CA 1 ATOM 479 C C . ASP A 1 65 ? 32.555 -19.090 -16.788 1.00 31.26 ? 65 ASP A C 1 ATOM 480 O O . ASP A 1 65 ? 32.640 -20.314 -16.653 1.00 32.01 ? 65 ASP A O 1 ATOM 481 C CB . ASP A 1 65 ? 35.018 -18.595 -16.826 1.00 32.50 ? 65 ASP A CB 1 ATOM 482 C CG . ASP A 1 65 ? 35.195 -18.147 -18.286 1.00 35.15 ? 65 ASP A CG 1 ATOM 483 O OD1 . ASP A 1 65 ? 34.183 -18.073 -19.027 1.00 35.89 ? 65 ASP A OD1 1 ATOM 484 O OD2 . ASP A 1 65 ? 36.332 -17.838 -18.698 1.00 35.37 ? 65 ASP A OD2 1 ATOM 485 N N . ALA A 1 66 ? 31.537 -18.480 -17.398 1.00 29.48 ? 66 ALA A N 1 ATOM 486 C CA . ALA A 1 66 ? 30.411 -19.218 -17.981 1.00 27.78 ? 66 ALA A CA 1 ATOM 487 C C . ALA A 1 66 ? 30.852 -20.150 -19.104 1.00 29.00 ? 66 ALA A C 1 ATOM 488 O O . ALA A 1 66 ? 30.300 -21.251 -19.271 1.00 27.71 ? 66 ALA A O 1 ATOM 489 C CB . ALA A 1 66 ? 29.392 -18.261 -18.497 1.00 28.58 ? 66 ALA A CB 1 ATOM 490 N N . SER A 1 67 ? 31.853 -19.708 -19.869 1.00 28.16 ? 67 SER A N 1 ATOM 491 C CA . SER A 1 67 ? 32.356 -20.484 -20.989 1.00 29.77 ? 67 SER A CA 1 ATOM 492 C C . SER A 1 67 ? 33.171 -21.708 -20.554 1.00 30.04 ? 67 SER A C 1 ATOM 493 O O . SER A 1 67 ? 33.703 -22.427 -21.395 1.00 29.53 ? 67 SER A O 1 ATOM 494 C CB . SER A 1 67 ? 33.137 -19.589 -21.970 1.00 30.07 ? 67 SER A CB 1 ATOM 495 O OG . SER A 1 67 ? 34.411 -19.267 -21.457 1.00 32.01 ? 67 SER A OG 1 ATOM 496 N N . ASP A 1 68 ? 33.261 -21.948 -19.245 1.00 30.91 ? 68 ASP A N 1 ATOM 497 C CA . ASP A 1 68 ? 33.846 -23.196 -18.734 1.00 31.06 ? 68 ASP A CA 1 ATOM 498 C C . ASP A 1 68 ? 32.823 -24.107 -18.068 1.00 29.39 ? 68 ASP A C 1 ATOM 499 O O . ASP A 1 68 ? 33.180 -25.176 -17.571 1.00 29.31 ? 68 ASP A O 1 ATOM 500 C CB . ASP A 1 68 ? 35.009 -22.914 -17.781 1.00 34.65 ? 68 ASP A CB 1 ATOM 501 C CG . ASP A 1 68 ? 36.198 -22.300 -18.490 1.00 37.53 ? 68 ASP A CG 1 ATOM 502 O OD1 . ASP A 1 68 ? 36.498 -22.743 -19.619 1.00 38.37 ? 68 ASP A OD1 1 ATOM 503 O OD2 . ASP A 1 68 ? 36.829 -21.371 -17.931 1.00 39.44 ? 68 ASP A OD2 1 ATOM 504 N N . SER A 1 69 ? 31.554 -23.696 -18.084 1.00 26.88 ? 69 SER A N 1 ATOM 505 C CA . SER A 1 69 ? 30.487 -24.449 -17.425 1.00 26.00 ? 69 SER A CA 1 ATOM 506 C C . SER A 1 69 ? 29.482 -25.017 -18.431 1.00 26.32 ? 69 SER A C 1 ATOM 507 O O . SER A 1 69 ? 28.965 -24.293 -19.298 1.00 25.43 ? 69 SER A O 1 ATOM 508 C CB . SER A 1 69 ? 29.768 -23.579 -16.386 1.00 25.72 ? 69 SER A CB 1 ATOM 509 O OG . SER A 1 69 ? 28.657 -24.271 -15.815 1.00 26.71 ? 69 SER A OG 1 ATOM 510 N N . SER A 1 70 ? 29.191 -26.306 -18.306 1.00 25.80 ? 70 SER A N 1 ATOM 511 C CA . SER A 1 70 ? 28.300 -26.958 -19.255 1.00 28.38 ? 70 SER A CA 1 ATOM 512 C C . SER A 1 70 ? 26.841 -26.833 -18.825 1.00 29.60 ? 70 SER A C 1 ATOM 513 O O . SER A 1 70 ? 25.916 -27.043 -19.623 1.00 30.37 ? 70 SER A O 1 ATOM 514 C CB . SER A 1 70 ? 28.694 -28.422 -19.441 1.00 29.51 ? 70 SER A CB 1 ATOM 515 O OG . SER A 1 70 ? 28.578 -29.140 -18.227 1.00 30.69 ? 70 SER A OG 1 ATOM 516 N N . SER A 1 71 ? 26.638 -26.474 -17.561 1.00 30.01 ? 71 SER A N 1 ATOM 517 C CA . SER A 1 71 ? 25.297 -26.393 -17.004 1.00 29.77 ? 71 SER A CA 1 ATOM 518 C C . SER A 1 71 ? 24.784 -24.964 -16.926 1.00 30.25 ? 71 SER A C 1 ATOM 519 O O . SER A 1 71 ? 23.666 -24.745 -16.463 1.00 30.66 ? 71 SER A O 1 ATOM 520 C CB . SER A 1 71 ? 25.255 -27.061 -15.630 1.00 29.62 ? 71 SER A CB 1 ATOM 521 O OG . SER A 1 71 ? 26.327 -26.616 -14.831 1.00 29.75 ? 71 SER A OG 1 ATOM 522 N N . TYR A 1 72 ? 25.599 -24.010 -17.389 1.00 29.55 ? 72 TYR A N 1 ATOM 523 C CA . TYR A 1 72 ? 25.273 -22.570 -17.374 1.00 31.04 ? 72 TYR A CA 1 ATOM 524 C C . TYR A 1 72 ? 24.163 -22.204 -18.349 1.00 30.96 ? 72 TYR A C 1 ATOM 525 O O . TYR A 1 72 ? 24.220 -22.577 -19.512 1.00 32.08 ? 72 TYR A O 1 ATOM 526 C CB . TYR A 1 72 ? 26.535 -21.733 -17.672 1.00 31.53 ? 72 TYR A CB 1 ATOM 527 C CG . TYR A 1 72 ? 26.299 -20.324 -18.214 1.00 30.90 ? 72 TYR A CG 1 ATOM 528 C CD1 . TYR A 1 72 ? 26.289 -20.080 -19.589 1.00 30.90 ? 72 TYR A CD1 1 ATOM 529 C CD2 . TYR A 1 72 ? 26.127 -19.239 -17.353 1.00 31.25 ? 72 TYR A CD2 1 ATOM 530 C CE1 . TYR A 1 72 ? 26.089 -18.803 -20.095 1.00 31.92 ? 72 TYR A CE1 1 ATOM 531 C CE2 . TYR A 1 72 ? 25.921 -17.949 -17.842 1.00 31.56 ? 72 TYR A CE2 1 ATOM 532 C CZ . TYR A 1 72 ? 25.904 -17.733 -19.217 1.00 32.43 ? 72 TYR A CZ 1 ATOM 533 O OH . TYR A 1 72 ? 25.704 -16.459 -19.718 1.00 30.45 ? 72 TYR A OH 1 ATOM 534 N N . LYS A 1 73 ? 23.165 -21.471 -17.863 1.00 31.54 ? 73 LYS A N 1 ATOM 535 C CA . LYS A 1 73 ? 22.102 -20.938 -18.702 1.00 32.26 ? 73 LYS A CA 1 ATOM 536 C C . LYS A 1 73 ? 22.149 -19.414 -18.660 1.00 33.93 ? 73 LYS A C 1 ATOM 537 O O . LYS A 1 73 ? 21.917 -18.800 -17.610 1.00 32.44 ? 73 LYS A O 1 ATOM 538 C CB . LYS A 1 73 ? 20.717 -21.424 -18.255 1.00 32.90 ? 73 LYS A CB 1 ATOM 539 C CG . LYS A 1 73 ? 20.507 -22.935 -18.142 1.00 33.38 ? 73 LYS A CG 1 ATOM 540 C CD . LYS A 1 73 ? 20.264 -23.610 -19.473 1.00 34.41 ? 73 LYS A CD 1 ATOM 541 C CE . LYS A 1 73 ? 19.315 -24.815 -19.331 1.00 36.16 ? 73 LYS A CE 1 ATOM 542 N NZ . LYS A 1 73 ? 17.896 -24.448 -19.713 1.00 38.10 ? 73 LYS A NZ 1 ATOM 543 N N . HIS A 1 74 ? 22.467 -18.825 -19.811 1.00 34.62 ? 74 HIS A N 1 ATOM 544 C CA . HIS A 1 74 ? 22.517 -17.382 -20.014 1.00 37.26 ? 74 HIS A CA 1 ATOM 545 C C . HIS A 1 74 ? 21.199 -16.697 -19.660 1.00 38.71 ? 74 HIS A C 1 ATOM 546 O O . HIS A 1 74 ? 20.126 -17.253 -19.896 1.00 38.66 ? 74 HIS A O 1 ATOM 547 C CB . HIS A 1 74 ? 22.873 -17.101 -21.481 1.00 38.13 ? 74 HIS A CB 1 ATOM 548 C CG . HIS A 1 74 ? 22.727 -15.668 -21.887 1.00 39.52 ? 74 HIS A CG 1 ATOM 549 N ND1 . HIS A 1 74 ? 21.534 -15.138 -22.331 1.00 40.76 ? 74 HIS A ND1 1 ATOM 550 C CD2 . HIS A 1 74 ? 23.630 -14.658 -21.939 1.00 40.14 ? 74 HIS A CD2 1 ATOM 551 C CE1 . HIS A 1 74 ? 21.705 -13.861 -22.625 1.00 41.61 ? 74 HIS A CE1 1 ATOM 552 N NE2 . HIS A 1 74 ? 22.967 -13.544 -22.393 1.00 41.51 ? 74 HIS A NE2 1 ATOM 553 N N . ASN A 1 75 ? 21.288 -15.495 -19.088 1.00 39.81 ? 75 ASN A N 1 ATOM 554 C CA . ASN A 1 75 ? 20.117 -14.632 -18.905 1.00 40.70 ? 75 ASN A CA 1 ATOM 555 C C . ASN A 1 75 ? 20.407 -13.202 -19.369 1.00 39.71 ? 75 ASN A C 1 ATOM 556 O O . ASN A 1 75 ? 19.754 -12.704 -20.286 1.00 38.63 ? 75 ASN A O 1 ATOM 557 C CB . ASN A 1 75 ? 19.613 -14.665 -17.460 1.00 45.11 ? 75 ASN A CB 1 ATOM 558 C CG . ASN A 1 75 ? 18.392 -13.779 -17.241 1.00 49.37 ? 75 ASN A CG 1 ATOM 559 O OD1 . ASN A 1 75 ? 18.524 -12.570 -17.073 1.00 47.88 ? 75 ASN A OD1 1 ATOM 560 N ND2 . ASN A 1 75 ? 17.195 -14.393 -17.249 1.00 54.87 ? 75 ASN A ND2 1 ATOM 561 N N . GLY A 1 76 ? 21.382 -12.553 -18.731 1.00 37.74 ? 76 GLY A N 1 ATOM 562 C CA . GLY A 1 76 ? 21.872 -11.247 -19.174 1.00 36.92 ? 76 GLY A CA 1 ATOM 563 C C . GLY A 1 76 ? 21.167 -10.007 -18.632 1.00 36.55 ? 76 GLY A C 1 ATOM 564 O O . GLY A 1 76 ? 21.601 -8.892 -18.907 1.00 33.40 ? 76 GLY A O 1 ATOM 565 N N . THR A 1 77 ? 20.077 -10.187 -17.885 1.00 37.05 ? 77 THR A N 1 ATOM 566 C CA . THR A 1 77 ? 19.402 -9.055 -17.244 1.00 39.78 ? 77 THR A CA 1 ATOM 567 C C . THR A 1 77 ? 20.392 -8.271 -16.384 1.00 40.92 ? 77 THR A C 1 ATOM 568 O O . THR A 1 77 ? 20.969 -8.807 -15.441 1.00 41.48 ? 77 THR A O 1 ATOM 569 C CB . THR A 1 77 ? 18.197 -9.503 -16.389 1.00 39.47 ? 77 THR A CB 1 ATOM 570 O OG1 . THR A 1 77 ? 17.205 -10.097 -17.237 1.00 39.47 ? 77 THR A OG1 1 ATOM 571 C CG2 . THR A 1 77 ? 17.580 -8.322 -15.671 1.00 40.18 ? 77 THR A CG2 1 ATOM 572 N N . GLU A 1 78 ? 20.611 -7.015 -16.749 1.00 42.40 ? 78 GLU A N 1 ATOM 573 C CA . GLU A 1 78 ? 21.480 -6.129 -15.999 1.00 46.66 ? 78 GLU A CA 1 ATOM 574 C C . GLU A 1 78 ? 20.868 -5.871 -14.627 1.00 45.58 ? 78 GLU A C 1 ATOM 575 O O . GLU A 1 78 ? 19.685 -5.557 -14.518 1.00 45.63 ? 78 GLU A O 1 ATOM 576 C CB . GLU A 1 78 ? 21.704 -4.808 -16.757 1.00 48.29 ? 78 GLU A CB 1 ATOM 577 C CG . GLU A 1 78 ? 22.521 -4.953 -18.061 1.00 50.43 ? 78 GLU A CG 1 ATOM 578 C CD . GLU A 1 78 ? 22.758 -3.622 -18.808 1.00 51.89 ? 78 GLU A CD 1 ATOM 579 O OE1 . GLU A 1 78 ? 22.023 -2.625 -18.567 1.00 52.48 ? 78 GLU A OE1 1 ATOM 580 O OE2 . GLU A 1 78 ? 23.690 -3.581 -19.652 1.00 53.77 ? 78 GLU A OE2 1 ATOM 581 N N . LEU A 1 79 ? 21.668 -6.051 -13.579 1.00 46.13 ? 79 LEU A N 1 ATOM 582 C CA . LEU A 1 79 ? 21.234 -5.709 -12.228 1.00 46.05 ? 79 LEU A CA 1 ATOM 583 C C . LEU A 1 79 ? 22.303 -4.982 -11.431 1.00 46.32 ? 79 LEU A C 1 ATOM 584 O O . LEU A 1 79 ? 23.511 -5.180 -11.646 1.00 44.55 ? 79 LEU A O 1 ATOM 585 C CB . LEU A 1 79 ? 20.654 -6.919 -11.480 1.00 47.69 ? 79 LEU A CB 1 ATOM 586 C CG . LEU A 1 79 ? 21.415 -8.034 -10.764 1.00 47.99 ? 79 LEU A CG 1 ATOM 587 C CD1 . LEU A 1 79 ? 20.411 -8.809 -9.930 1.00 46.95 ? 79 LEU A CD1 1 ATOM 588 C CD2 . LEU A 1 79 ? 22.116 -8.962 -11.734 1.00 48.24 ? 79 LEU A CD2 1 ATOM 589 N N . THR A 1 80 ? 21.822 -4.129 -10.523 1.00 47.61 ? 80 THR A N 1 ATOM 590 C CA . THR A 1 80 ? 22.625 -3.122 -9.836 1.00 47.93 ? 80 THR A CA 1 ATOM 591 C C . THR A 1 80 ? 22.314 -3.088 -8.346 1.00 48.59 ? 80 THR A C 1 ATOM 592 O O . THR A 1 80 ? 21.152 -3.064 -7.949 1.00 49.89 ? 80 THR A O 1 ATOM 593 C CB . THR A 1 80 ? 22.336 -1.716 -10.427 1.00 48.40 ? 80 THR A CB 1 ATOM 594 O OG1 . THR A 1 80 ? 22.719 -1.681 -11.806 1.00 48.34 ? 80 THR A OG1 1 ATOM 595 C CG2 . THR A 1 80 ? 23.082 -0.625 -9.668 1.00 48.23 ? 80 THR A CG2 1 ATOM 596 N N . LEU A 1 81 ? 23.360 -3.082 -7.530 1.00 49.53 ? 81 LEU A N 1 ATOM 597 C CA . LEU A 1 81 ? 23.240 -2.855 -6.095 1.00 50.35 ? 81 LEU A CA 1 ATOM 598 C C . LEU A 1 81 ? 23.811 -1.477 -5.759 1.00 51.96 ? 81 LEU A C 1 ATOM 599 O O . LEU A 1 81 ? 24.930 -1.138 -6.158 1.00 50.16 ? 81 LEU A O 1 ATOM 600 C CB . LEU A 1 81 ? 23.998 -3.929 -5.321 1.00 49.62 ? 81 LEU A CB 1 ATOM 601 C CG . LEU A 1 81 ? 23.799 -4.203 -3.827 1.00 50.00 ? 81 LEU A CG 1 ATOM 602 C CD1 . LEU A 1 81 ? 25.157 -4.137 -3.133 1.00 49.70 ? 81 LEU A CD1 1 ATOM 603 C CD2 . LEU A 1 81 ? 22.798 -3.289 -3.113 1.00 49.52 ? 81 LEU A CD2 1 ATOM 604 N N . ARG A 1 82 ? 23.032 -0.691 -5.026 1.00 56.07 ? 82 ARG A N 1 ATOM 605 C CA . ARG A 1 82 ? 23.460 0.635 -4.594 1.00 60.62 ? 82 ARG A CA 1 ATOM 606 C C . ARG A 1 82 ? 24.163 0.576 -3.240 1.00 61.07 ? 82 ARG A C 1 ATOM 607 O O . ARG A 1 82 ? 23.524 0.382 -2.202 1.00 61.45 ? 82 ARG A O 1 ATOM 608 C CB . ARG A 1 82 ? 22.275 1.601 -4.560 1.00 63.60 ? 82 ARG A CB 1 ATOM 609 C CG . ARG A 1 82 ? 21.695 1.907 -5.937 1.00 67.20 ? 82 ARG A CG 1 ATOM 610 C CD . ARG A 1 82 ? 20.448 2.765 -5.820 1.00 70.40 ? 82 ARG A CD 1 ATOM 611 N NE . ARG A 1 82 ? 20.274 3.642 -6.978 1.00 73.34 ? 82 ARG A NE 1 ATOM 612 C CZ . ARG A 1 82 ? 20.863 4.831 -7.122 1.00 75.20 ? 82 ARG A CZ 1 ATOM 613 N NH1 . ARG A 1 82 ? 21.679 5.302 -6.180 1.00 75.02 ? 82 ARG A NH1 1 ATOM 614 N NH2 . ARG A 1 82 ? 20.635 5.555 -8.217 1.00 75.69 ? 82 ARG A NH2 1 ATOM 615 N N . TYR A 1 83 ? 25.486 0.718 -3.278 1.00 61.62 ? 83 TYR A N 1 ATOM 616 C CA . TYR A 1 83 ? 26.321 0.765 -2.080 1.00 61.77 ? 83 TYR A CA 1 ATOM 617 C C . TYR A 1 83 ? 26.757 2.212 -1.808 1.00 61.57 ? 83 TYR A C 1 ATOM 618 O O . TYR A 1 83 ? 26.676 3.062 -2.699 1.00 61.74 ? 83 TYR A O 1 ATOM 619 C CB . TYR A 1 83 ? 27.527 -0.172 -2.238 1.00 61.78 ? 83 TYR A CB 1 ATOM 620 C CG . TYR A 1 83 ? 28.136 -0.606 -0.921 1.00 62.32 ? 83 TYR A CG 1 ATOM 621 C CD1 . TYR A 1 83 ? 29.435 -0.236 -0.575 1.00 62.12 ? 83 TYR A CD1 1 ATOM 622 C CD2 . TYR A 1 83 ? 27.405 -1.372 -0.010 1.00 61.56 ? 83 TYR A CD2 1 ATOM 623 C CE1 . TYR A 1 83 ? 29.991 -0.623 0.640 1.00 62.22 ? 83 TYR A CE1 1 ATOM 624 C CE2 . TYR A 1 83 ? 27.949 -1.758 1.203 1.00 61.71 ? 83 TYR A CE2 1 ATOM 625 C CZ . TYR A 1 83 ? 29.243 -1.384 1.522 1.00 62.00 ? 83 TYR A CZ 1 ATOM 626 O OH . TYR A 1 83 ? 29.786 -1.771 2.723 1.00 62.02 ? 83 TYR A OH 1 ATOM 627 N N . SER A 1 84 ? 27.202 2.497 -0.585 1.00 61.01 ? 84 SER A N 1 ATOM 628 C CA . SER A 1 84 ? 27.544 3.876 -0.194 1.00 61.64 ? 84 SER A CA 1 ATOM 629 C C . SER A 1 84 ? 28.783 4.438 -0.908 1.00 61.42 ? 84 SER A C 1 ATOM 630 O O . SER A 1 84 ? 28.887 5.643 -1.127 1.00 61.50 ? 84 SER A O 1 ATOM 631 C CB . SER A 1 84 ? 27.716 3.989 1.325 1.00 61.36 ? 84 SER A CB 1 ATOM 632 O OG . SER A 1 84 ? 28.742 3.127 1.789 1.00 61.41 ? 84 SER A OG 1 ATOM 633 N N . THR A 1 85 ? 29.706 3.551 -1.272 1.00 60.69 ? 85 THR A N 1 ATOM 634 C CA . THR A 1 85 ? 30.986 3.933 -1.876 1.00 59.63 ? 85 THR A CA 1 ATOM 635 C C . THR A 1 85 ? 30.924 3.979 -3.410 1.00 58.46 ? 85 THR A C 1 ATOM 636 O O . THR A 1 85 ? 31.910 4.339 -4.078 1.00 57.77 ? 85 THR A O 1 ATOM 637 C CB . THR A 1 85 ? 32.109 2.964 -1.439 1.00 59.66 ? 85 THR A CB 1 ATOM 638 O OG1 . THR A 1 85 ? 31.764 1.623 -1.815 1.00 59.76 ? 85 THR A OG1 1 ATOM 639 C CG2 . THR A 1 85 ? 32.303 3.023 0.074 1.00 60.44 ? 85 THR A CG2 1 ATOM 640 N N . GLY A 1 86 ? 29.762 3.619 -3.952 1.00 56.69 ? 86 GLY A N 1 ATOM 641 C CA . GLY A 1 86 ? 29.564 3.498 -5.395 1.00 55.00 ? 86 GLY A CA 1 ATOM 642 C C . GLY A 1 86 ? 28.591 2.390 -5.747 1.00 53.62 ? 86 GLY A C 1 ATOM 643 O O . GLY A 1 86 ? 27.959 1.798 -4.869 1.00 54.62 ? 86 GLY A O 1 ATOM 644 N N . THR A 1 87 ? 28.475 2.105 -7.040 1.00 51.49 ? 87 THR A N 1 ATOM 645 C CA . THR A 1 87 ? 27.533 1.102 -7.543 1.00 47.88 ? 87 THR A CA 1 ATOM 646 C C . THR A 1 87 ? 28.210 -0.243 -7.815 1.00 44.41 ? 87 THR A C 1 ATOM 647 O O . THR A 1 87 ? 29.341 -0.298 -8.295 1.00 43.60 ? 87 THR A O 1 ATOM 648 C CB . THR A 1 87 ? 26.792 1.623 -8.806 1.00 48.54 ? 87 THR A CB 1 ATOM 649 O OG1 . THR A 1 87 ? 25.593 2.298 -8.409 1.00 49.51 ? 87 THR A OG1 1 ATOM 650 C CG2 . THR A 1 87 ? 26.418 0.503 -9.752 1.00 49.50 ? 87 THR A CG2 1 ATOM 651 N N . VAL A 1 88 ? 27.506 -1.316 -7.468 1.00 42.29 ? 88 VAL A N 1 ATOM 652 C CA . VAL A 1 88 ? 27.884 -2.678 -7.834 1.00 39.09 ? 88 VAL A CA 1 ATOM 653 C C . VAL A 1 88 ? 26.932 -3.079 -8.939 1.00 37.63 ? 88 VAL A C 1 ATOM 654 O O . VAL A 1 88 ? 25.722 -3.050 -8.748 1.00 39.40 ? 88 VAL A O 1 ATOM 655 C CB . VAL A 1 88 ? 27.699 -3.663 -6.653 1.00 37.34 ? 88 VAL A CB 1 ATOM 656 C CG1 . VAL A 1 88 ? 27.964 -5.105 -7.099 1.00 36.54 ? 88 VAL A CG1 1 ATOM 657 C CG2 . VAL A 1 88 ? 28.593 -3.290 -5.495 1.00 36.31 ? 88 VAL A CG2 1 ATOM 658 N N . SER A 1 89 ? 27.454 -3.432 -10.102 1.00 36.66 ? 89 SER A N 1 ATOM 659 C CA . SER A 1 89 ? 26.568 -3.866 -11.179 1.00 36.69 ? 89 SER A CA 1 ATOM 660 C C . SER A 1 89 ? 27.077 -5.111 -11.896 1.00 35.58 ? 89 SER A C 1 ATOM 661 O O . SER A 1 89 ? 28.267 -5.423 -11.871 1.00 33.73 ? 89 SER A O 1 ATOM 662 C CB . SER A 1 89 ? 26.315 -2.730 -12.175 1.00 36.31 ? 89 SER A CB 1 ATOM 663 O OG . SER A 1 89 ? 27.527 -2.310 -12.756 1.00 37.24 ? 89 SER A OG 1 ATOM 664 N N . GLY A 1 90 ? 26.152 -5.809 -12.538 1.00 34.89 ? 90 GLY A N 1 ATOM 665 C CA . GLY A 1 90 ? 26.461 -7.030 -13.250 1.00 33.81 ? 90 GLY A CA 1 ATOM 666 C C . GLY A 1 90 ? 25.217 -7.519 -13.948 1.00 35.37 ? 90 GLY A C 1 ATOM 667 O O . GLY A 1 90 ? 24.322 -6.728 -14.272 1.00 36.23 ? 90 GLY A O 1 ATOM 668 N N . PHE A 1 91 ? 25.147 -8.827 -14.171 1.00 35.24 ? 91 PHE A N 1 ATOM 669 C CA . PHE A 1 91 ? 24.040 -9.411 -14.925 1.00 33.26 ? 91 PHE A CA 1 ATOM 670 C C . PHE A 1 91 ? 23.656 -10.784 -14.390 1.00 32.64 ? 91 PHE A C 1 ATOM 671 O O . PHE A 1 91 ? 24.451 -11.441 -13.735 1.00 33.62 ? 91 PHE A O 1 ATOM 672 C CB . PHE A 1 91 ? 24.389 -9.463 -16.416 1.00 30.20 ? 91 PHE A CB 1 ATOM 673 C CG . PHE A 1 91 ? 25.645 -10.224 -16.722 1.00 28.52 ? 91 PHE A CG 1 ATOM 674 C CD1 . PHE A 1 91 ? 25.591 -11.591 -17.011 1.00 28.22 ? 91 PHE A CD1 1 ATOM 675 C CD2 . PHE A 1 91 ? 26.879 -9.578 -16.742 1.00 25.42 ? 91 PHE A CD2 1 ATOM 676 C CE1 . PHE A 1 91 ? 26.757 -12.300 -17.298 1.00 28.62 ? 91 PHE A CE1 1 ATOM 677 C CE2 . PHE A 1 91 ? 28.041 -10.277 -17.027 1.00 25.36 ? 91 PHE A CE2 1 ATOM 678 C CZ . PHE A 1 91 ? 27.990 -11.630 -17.301 1.00 28.03 ? 91 PHE A CZ 1 ATOM 679 N N . LEU A 1 92 ? 22.424 -11.195 -14.654 1.00 33.61 ? 92 LEU A N 1 ATOM 680 C CA . LEU A 1 92 ? 21.921 -12.483 -14.193 1.00 34.16 ? 92 LEU A CA 1 ATOM 681 C C . LEU A 1 92 ? 22.424 -13.625 -15.056 1.00 33.22 ? 92 LEU A C 1 ATOM 682 O O . LEU A 1 92 ? 22.455 -13.509 -16.284 1.00 30.01 ? 92 LEU A O 1 ATOM 683 C CB . LEU A 1 92 ? 20.395 -12.513 -14.221 1.00 36.38 ? 92 LEU A CB 1 ATOM 684 C CG . LEU A 1 92 ? 19.566 -11.854 -13.120 1.00 39.83 ? 92 LEU A CG 1 ATOM 685 C CD1 . LEU A 1 92 ? 18.111 -12.261 -13.336 1.00 39.54 ? 92 LEU A CD1 1 ATOM 686 C CD2 . LEU A 1 92 ? 20.043 -12.252 -11.708 1.00 39.99 ? 92 LEU A CD2 1 ATOM 687 N N . SER A 1 93 ? 22.814 -14.712 -14.383 1.00 32.34 ? 93 SER A N 1 ATOM 688 C CA . SER A 1 93 ? 23.141 -16.000 -14.993 1.00 31.41 ? 93 SER A CA 1 ATOM 689 C C . SER A 1 93 ? 22.522 -17.102 -14.137 1.00 32.55 ? 93 SER A C 1 ATOM 690 O O . SER A 1 93 ? 22.262 -16.908 -12.941 1.00 33.77 ? 93 SER A O 1 ATOM 691 C CB . SER A 1 93 ? 24.653 -16.223 -15.023 1.00 31.70 ? 93 SER A CB 1 ATOM 692 O OG . SER A 1 93 ? 25.334 -15.198 -15.710 1.00 29.76 ? 93 SER A OG 1 ATOM 693 N N . GLN A 1 94 ? 22.301 -18.265 -14.731 1.00 30.69 ? 94 GLN A N 1 ATOM 694 C CA . GLN A 1 94 ? 21.863 -19.413 -13.965 1.00 29.91 ? 94 GLN A CA 1 ATOM 695 C C . GLN A 1 94 ? 22.895 -20.534 -14.059 1.00 31.08 ? 94 GLN A C 1 ATOM 696 O O . GLN A 1 94 ? 23.506 -20.747 -15.111 1.00 31.94 ? 94 GLN A O 1 ATOM 697 C CB . GLN A 1 94 ? 20.501 -19.884 -14.458 1.00 30.90 ? 94 GLN A CB 1 ATOM 698 C CG . GLN A 1 94 ? 19.900 -21.021 -13.671 1.00 32.05 ? 94 GLN A CG 1 ATOM 699 C CD . GLN A 1 94 ? 18.639 -21.538 -14.318 1.00 34.71 ? 94 GLN A CD 1 ATOM 700 O OE1 . GLN A 1 94 ? 17.569 -20.940 -14.181 1.00 36.60 ? 94 GLN A OE1 1 ATOM 701 N NE2 . GLN A 1 94 ? 18.753 -22.656 -15.032 1.00 34.37 ? 94 GLN A NE2 1 ATOM 702 N N . ASP A 1 95 ? 23.114 -21.233 -12.949 1.00 29.27 ? 95 ASP A N 1 ATOM 703 C CA . ASP A 1 95 ? 23.972 -22.404 -12.966 1.00 28.24 ? 95 ASP A CA 1 ATOM 704 C C . ASP A 1 95 ? 23.683 -23.241 -11.735 1.00 28.46 ? 95 ASP A C 1 ATOM 705 O O . ASP A 1 95 ? 22.832 -22.880 -10.934 1.00 27.11 ? 95 ASP A O 1 ATOM 706 C CB . ASP A 1 95 ? 25.457 -22.012 -13.047 1.00 26.48 ? 95 ASP A CB 1 ATOM 707 C CG . ASP A 1 95 ? 26.282 -22.989 -13.905 1.00 26.73 ? 95 ASP A CG 1 ATOM 708 O OD1 . ASP A 1 95 ? 26.161 -24.222 -13.704 1.00 24.13 ? 95 ASP A OD1 1 ATOM 709 O OD2 . ASP A 1 95 ? 27.064 -22.517 -14.774 1.00 25.45 ? 95 ASP A OD2 1 ATOM 710 N N . ILE A 1 96 ? 24.385 -24.365 -11.614 1.00 29.97 ? 96 ILE A N 1 ATOM 711 C CA . ILE A 1 96 ? 24.243 -25.284 -10.498 1.00 32.33 ? 96 ILE A CA 1 ATOM 712 C C . ILE A 1 96 ? 25.177 -24.826 -9.379 1.00 32.49 ? 96 ILE A C 1 ATOM 713 O O . ILE A 1 96 ? 26.391 -24.735 -9.581 1.00 33.93 ? 96 ILE A O 1 ATOM 714 C CB . ILE A 1 96 ? 24.584 -26.722 -10.962 1.00 34.45 ? 96 ILE A CB 1 ATOM 715 C CG1 . ILE A 1 96 ? 23.385 -27.357 -11.691 1.00 36.41 ? 96 ILE A CG1 1 ATOM 716 C CG2 . ILE A 1 96 ? 25.018 -27.594 -9.810 1.00 35.31 ? 96 ILE A CG2 1 ATOM 717 C CD1 . ILE A 1 96 ? 23.760 -28.585 -12.501 1.00 36.67 ? 96 ILE A CD1 1 ATOM 718 N N . ILE A 1 97 ? 24.611 -24.522 -8.214 1.00 30.70 ? 97 ILE A N 1 ATOM 719 C CA . ILE A 1 97 ? 25.406 -24.103 -7.056 1.00 29.19 ? 97 ILE A CA 1 ATOM 720 C C . ILE A 1 97 ? 25.422 -25.175 -5.971 1.00 29.14 ? 97 ILE A C 1 ATOM 721 O O . ILE A 1 97 ? 24.379 -25.627 -5.512 1.00 29.64 ? 97 ILE A O 1 ATOM 722 C CB . ILE A 1 97 ? 24.952 -22.733 -6.480 1.00 27.28 ? 97 ILE A CB 1 ATOM 723 C CG1 . ILE A 1 97 ? 25.169 -21.636 -7.527 1.00 28.08 ? 97 ILE A CG1 1 ATOM 724 C CG2 . ILE A 1 97 ? 25.746 -22.392 -5.201 1.00 27.67 ? 97 ILE A CG2 1 ATOM 725 C CD1 . ILE A 1 97 ? 24.745 -20.236 -7.107 1.00 28.10 ? 97 ILE A CD1 1 ATOM 726 N N . THR A 1 98 ? 26.622 -25.595 -5.590 1.00 29.53 ? 98 THR A N 1 ATOM 727 C CA . THR A 1 98 ? 26.793 -26.574 -4.523 1.00 30.58 ? 98 THR A CA 1 ATOM 728 C C . THR A 1 98 ? 27.219 -25.867 -3.237 1.00 30.33 ? 98 THR A C 1 ATOM 729 O O . THR A 1 98 ? 28.179 -25.093 -3.230 1.00 28.44 ? 98 THR A O 1 ATOM 730 C CB . THR A 1 98 ? 27.822 -27.660 -4.905 1.00 31.73 ? 98 THR A CB 1 ATOM 731 O OG1 . THR A 1 98 ? 28.976 -27.025 -5.473 1.00 36.04 ? 98 THR A OG1 1 ATOM 732 C CG2 . THR A 1 98 ? 27.240 -28.603 -5.946 1.00 31.12 ? 98 THR A CG2 1 ATOM 733 N N . VAL A 1 99 ? 26.459 -26.112 -2.174 1.00 32.07 ? 99 VAL A N 1 ATOM 734 C CA . VAL A 1 99 ? 26.707 -25.558 -0.848 1.00 34.44 ? 99 VAL A CA 1 ATOM 735 C C . VAL A 1 99 ? 26.691 -26.737 0.115 1.00 36.45 ? 99 VAL A C 1 ATOM 736 O O . VAL A 1 99 ? 25.650 -27.371 0.318 1.00 35.74 ? 99 VAL A O 1 ATOM 737 C CB . VAL A 1 99 ? 25.614 -24.554 -0.429 1.00 35.56 ? 99 VAL A CB 1 ATOM 738 C CG1 . VAL A 1 99 ? 25.937 -23.943 0.951 1.00 36.57 ? 99 VAL A CG1 1 ATOM 739 C CG2 . VAL A 1 99 ? 25.450 -23.458 -1.470 1.00 35.52 ? 99 VAL A CG2 1 ATOM 740 N N . GLY A 1 100 ? 27.847 -27.034 0.702 1.00 38.69 ? 100 GLY A N 1 ATOM 741 C CA . GLY A 1 100 ? 27.992 -28.241 1.511 1.00 39.97 ? 100 GLY A CA 1 ATOM 742 C C . GLY A 1 100 ? 27.631 -29.465 0.682 1.00 40.47 ? 100 GLY A C 1 ATOM 743 O O . GLY A 1 100 ? 28.203 -29.696 -0.396 1.00 41.22 ? 100 GLY A O 1 ATOM 744 N N . GLY A 1 101 ? 26.663 -30.236 1.162 1.00 39.57 ? 101 GLY A N 1 ATOM 745 C CA . GLY A 1 101 ? 26.243 -31.431 0.437 1.00 39.58 ? 101 GLY A CA 1 ATOM 746 C C . GLY A 1 101 ? 25.060 -31.224 -0.494 1.00 39.78 ? 101 GLY A C 1 ATOM 747 O O . GLY A 1 101 ? 24.477 -32.196 -0.985 1.00 41.83 ? 101 GLY A O 1 ATOM 748 N N . ILE A 1 102 ? 24.721 -29.965 -0.759 1.00 37.25 ? 102 ILE A N 1 ATOM 749 C CA . ILE A 1 102 ? 23.478 -29.627 -1.434 1.00 36.27 ? 102 ILE A CA 1 ATOM 750 C C . ILE A 1 102 ? 23.711 -28.969 -2.796 1.00 36.49 ? 102 ILE A C 1 ATOM 751 O O . ILE A 1 102 ? 24.481 -28.022 -2.907 1.00 36.70 ? 102 ILE A O 1 ATOM 752 C CB . ILE A 1 102 ? 22.589 -28.730 -0.528 1.00 36.25 ? 102 ILE A CB 1 ATOM 753 C CG1 . ILE A 1 102 ? 22.020 -29.552 0.634 1.00 35.38 ? 102 ILE A CG1 1 ATOM 754 C CG2 . ILE A 1 102 ? 21.466 -28.067 -1.329 1.00 36.43 ? 102 ILE A CG2 1 ATOM 755 C CD1 . ILE A 1 102 ? 21.310 -28.722 1.701 1.00 35.95 ? 102 ILE A CD1 1 ATOM 756 N N . THR A 1 103 ? 23.033 -29.477 -3.822 1.00 35.22 ? 103 THR A N 1 ATOM 757 C CA . THR A 1 103 ? 23.119 -28.909 -5.157 1.00 35.17 ? 103 THR A CA 1 ATOM 758 C C . THR A 1 103 ? 21.809 -28.210 -5.520 1.00 34.00 ? 103 THR A C 1 ATOM 759 O O . THR A 1 103 ? 20.726 -28.776 -5.398 1.00 34.76 ? 103 THR A O 1 ATOM 760 C CB . THR A 1 103 ? 23.482 -29.977 -6.230 1.00 36.06 ? 103 THR A CB 1 ATOM 761 O OG1 . THR A 1 103 ? 24.692 -30.650 -5.857 1.00 38.37 ? 103 THR A OG1 1 ATOM 762 C CG2 . THR A 1 103 ? 23.702 -29.326 -7.574 1.00 35.16 ? 103 THR A CG2 1 ATOM 763 N N . VAL A 1 104 ? 21.917 -26.975 -5.974 1.00 30.78 ? 104 VAL A N 1 ATOM 764 C CA . VAL A 1 104 ? 20.744 -26.232 -6.353 1.00 30.54 ? 104 VAL A CA 1 ATOM 765 C C . VAL A 1 104 ? 21.008 -25.411 -7.608 1.00 29.57 ? 104 VAL A C 1 ATOM 766 O O . VAL A 1 104 ? 22.042 -24.757 -7.726 1.00 29.68 ? 104 VAL A O 1 ATOM 767 C CB . VAL A 1 104 ? 20.231 -25.349 -5.159 1.00 29.87 ? 104 VAL A CB 1 ATOM 768 C CG1 . VAL A 1 104 ? 21.317 -24.460 -4.631 1.00 29.68 ? 104 VAL A CG1 1 ATOM 769 C CG2 . VAL A 1 104 ? 19.015 -24.546 -5.556 1.00 29.34 ? 104 VAL A CG2 1 ATOM 770 N N . THR A 1 105 ? 20.071 -25.473 -8.548 1.00 30.75 ? 105 THR A N 1 ATOM 771 C CA . THR A 1 105 ? 20.050 -24.585 -9.712 1.00 30.19 ? 105 THR A CA 1 ATOM 772 C C . THR A 1 105 ? 19.621 -23.214 -9.206 1.00 30.89 ? 105 THR A C 1 ATOM 773 O O . THR A 1 105 ? 18.621 -23.092 -8.476 1.00 31.18 ? 105 THR A O 1 ATOM 774 C CB . THR A 1 105 ? 19.061 -25.092 -10.784 1.00 30.82 ? 105 THR A CB 1 ATOM 775 O OG1 . THR A 1 105 ? 19.471 -26.388 -11.252 1.00 32.01 ? 105 THR A OG1 1 ATOM 776 C CG2 . THR A 1 105 ? 19.007 -24.144 -11.967 1.00 30.95 ? 105 THR A CG2 1 ATOM 777 N N . GLN A 1 106 ? 20.368 -22.182 -9.581 1.00 29.82 ? 106 GLN A N 1 ATOM 778 C CA . GLN A 1 106 ? 20.197 -20.872 -8.951 1.00 29.94 ? 106 GLN A CA 1 ATOM 779 C C . GLN A 1 106 ? 20.473 -19.723 -9.935 1.00 29.19 ? 106 GLN A C 1 ATOM 780 O O . GLN A 1 106 ? 21.376 -19.833 -10.748 1.00 29.53 ? 106 GLN A O 1 ATOM 781 C CB . GLN A 1 106 ? 21.144 -20.791 -7.738 1.00 28.20 ? 106 GLN A CB 1 ATOM 782 C CG . GLN A 1 106 ? 21.172 -19.454 -6.998 1.00 25.91 ? 106 GLN A CG 1 ATOM 783 C CD . GLN A 1 106 ? 19.863 -19.151 -6.318 1.00 25.79 ? 106 GLN A CD 1 ATOM 784 O OE1 . GLN A 1 106 ? 19.219 -20.043 -5.758 1.00 28.03 ? 106 GLN A OE1 1 ATOM 785 N NE2 . GLN A 1 106 ? 19.454 -17.889 -6.359 1.00 24.69 ? 106 GLN A NE2 1 ATOM 786 N N . MET A 1 107 ? 19.696 -18.641 -9.862 1.00 28.73 ? 107 MET A N 1 ATOM 787 C CA . MET A 1 107 ? 20.050 -17.408 -10.563 1.00 33.52 ? 107 MET A CA 1 ATOM 788 C C . MET A 1 107 ? 20.944 -16.584 -9.648 1.00 30.02 ? 107 MET A C 1 ATOM 789 O O . MET A 1 107 ? 20.693 -16.477 -8.446 1.00 29.36 ? 107 MET A O 1 ATOM 790 C CB . MET A 1 107 ? 18.813 -16.587 -11.002 1.00 35.98 ? 107 MET A CB 1 ATOM 791 C CG . MET A 1 107 ? 17.835 -17.314 -11.955 1.00 39.58 ? 107 MET A CG 1 ATOM 792 S SD . MET A 1 107 ? 17.718 -16.719 -13.665 1.00 43.21 ? 107 MET A SD 1 ATOM 793 C CE . MET A 1 107 ? 19.412 -16.273 -14.014 1.00 44.00 ? 107 MET A CE 1 ATOM 794 N N . PHE A 1 108 ? 22.002 -16.027 -10.223 1.00 27.23 ? 108 PHE A N 1 ATOM 795 C CA . PHE A 1 108 ? 22.955 -15.212 -9.481 1.00 27.20 ? 108 PHE A CA 1 ATOM 796 C C . PHE A 1 108 ? 23.463 -14.074 -10.366 1.00 28.34 ? 108 PHE A C 1 ATOM 797 O O . PHE A 1 108 ? 23.234 -14.063 -11.579 1.00 28.34 ? 108 PHE A O 1 ATOM 798 C CB . PHE A 1 108 ? 24.119 -16.066 -8.921 1.00 26.36 ? 108 PHE A CB 1 ATOM 799 C CG . PHE A 1 108 ? 24.929 -16.782 -9.972 1.00 26.28 ? 108 PHE A CG 1 ATOM 800 C CD1 . PHE A 1 108 ? 24.483 -17.979 -10.529 1.00 26.44 ? 108 PHE A CD1 1 ATOM 801 C CD2 . PHE A 1 108 ? 26.140 -16.256 -10.408 1.00 27.16 ? 108 PHE A CD2 1 ATOM 802 C CE1 . PHE A 1 108 ? 25.220 -18.631 -11.510 1.00 24.33 ? 108 PHE A CE1 1 ATOM 803 C CE2 . PHE A 1 108 ? 26.891 -16.897 -11.378 1.00 26.68 ? 108 PHE A CE2 1 ATOM 804 C CZ . PHE A 1 108 ? 26.425 -18.093 -11.934 1.00 26.88 ? 108 PHE A CZ 1 ATOM 805 N N . GLY A 1 109 ? 24.132 -13.107 -9.751 1.00 29.05 ? 109 GLY A N 1 ATOM 806 C CA . GLY A 1 109 ? 24.696 -12.001 -10.493 1.00 29.46 ? 109 GLY A CA 1 ATOM 807 C C . GLY A 1 109 ? 26.169 -12.237 -10.712 1.00 30.78 ? 109 GLY A C 1 ATOM 808 O O . GLY A 1 109 ? 26.873 -12.696 -9.813 1.00 30.53 ? 109 GLY A O 1 ATOM 809 N N . GLU A 1 110 ? 26.615 -11.950 -11.929 1.00 31.78 ? 110 GLU A N 1 ATOM 810 C CA . GLU A 1 110 ? 28.026 -11.904 -12.270 1.00 32.63 ? 110 GLU A CA 1 ATOM 811 C C . GLU A 1 110 ? 28.393 -10.439 -12.295 1.00 33.37 ? 110 GLU A C 1 ATOM 812 O O . GLU A 1 110 ? 27.795 -9.669 -13.055 1.00 32.93 ? 110 GLU A O 1 ATOM 813 C CB . GLU A 1 110 ? 28.261 -12.481 -13.662 1.00 31.38 ? 110 GLU A CB 1 ATOM 814 C CG . GLU A 1 110 ? 28.156 -13.970 -13.760 1.00 32.77 ? 110 GLU A CG 1 ATOM 815 C CD . GLU A 1 110 ? 28.625 -14.495 -15.116 1.00 33.40 ? 110 GLU A CD 1 ATOM 816 O OE1 . GLU A 1 110 ? 29.731 -14.116 -15.577 1.00 32.69 ? 110 GLU A OE1 1 ATOM 817 O OE2 . GLU A 1 110 ? 27.880 -15.298 -15.711 1.00 34.32 ? 110 GLU A OE2 1 ATOM 818 N N . VAL A 1 111 ? 29.366 -10.057 -11.474 1.00 33.41 ? 111 VAL A N 1 ATOM 819 C CA . VAL A 1 111 ? 29.699 -8.646 -11.279 1.00 34.25 ? 111 VAL A CA 1 ATOM 820 C C . VAL A 1 111 ? 30.731 -8.198 -12.309 1.00 34.57 ? 111 VAL A C 1 ATOM 821 O O . VAL A 1 111 ? 31.742 -8.867 -12.511 1.00 33.92 ? 111 VAL A O 1 ATOM 822 C CB . VAL A 1 111 ? 30.183 -8.368 -9.831 1.00 34.11 ? 111 VAL A CB 1 ATOM 823 C CG1 . VAL A 1 111 ? 30.763 -6.963 -9.693 1.00 33.57 ? 111 VAL A CG1 1 ATOM 824 C CG2 . VAL A 1 111 ? 29.034 -8.554 -8.861 1.00 34.93 ? 111 VAL A CG2 1 ATOM 825 N N . THR A 1 112 ? 30.450 -7.076 -12.968 1.00 33.89 ? 112 THR A N 1 ATOM 826 C CA . THR A 1 112 ? 31.327 -6.536 -14.003 1.00 33.06 ? 112 THR A CA 1 ATOM 827 C C . THR A 1 112 ? 32.005 -5.247 -13.558 1.00 35.68 ? 112 THR A C 1 ATOM 828 O O . THR A 1 112 ? 33.031 -4.874 -14.104 1.00 37.29 ? 112 THR A O 1 ATOM 829 C CB . THR A 1 112 ? 30.567 -6.304 -15.308 1.00 32.82 ? 112 THR A CB 1 ATOM 830 O OG1 . THR A 1 112 ? 29.520 -5.347 -15.096 1.00 34.26 ? 112 THR A OG1 1 ATOM 831 C CG2 . THR A 1 112 ? 29.957 -7.609 -15.803 1.00 31.01 ? 112 THR A CG2 1 ATOM 832 N N . GLU A 1 113 ? 31.422 -4.565 -12.571 1.00 38.19 ? 113 GLU A N 1 ATOM 833 C CA . GLU A 1 113 ? 32.077 -3.437 -11.903 1.00 40.86 ? 113 GLU A CA 1 ATOM 834 C C . GLU A 1 113 ? 31.610 -3.249 -10.462 1.00 40.91 ? 113 GLU A C 1 ATOM 835 O O . GLU A 1 113 ? 30.438 -3.493 -10.117 1.00 40.21 ? 113 GLU A O 1 ATOM 836 C CB . GLU A 1 113 ? 31.935 -2.126 -12.699 1.00 41.12 ? 113 GLU A CB 1 ATOM 837 C CG . GLU A 1 113 ? 30.516 -1.689 -12.940 1.00 44.26 ? 113 GLU A CG 1 ATOM 838 C CD . GLU A 1 113 ? 30.379 -0.610 -14.000 1.00 45.10 ? 113 GLU A CD 1 ATOM 839 O OE1 . GLU A 1 113 ? 29.275 -0.048 -14.108 1.00 48.43 ? 113 GLU A OE1 1 ATOM 840 O OE2 . GLU A 1 113 ? 31.344 -0.327 -14.734 1.00 47.09 ? 113 GLU A OE2 1 ATOM 841 N N . MET A 1 114 ? 32.549 -2.798 -9.633 1.00 41.26 ? 114 MET A N 1 ATOM 842 C CA . MET A 1 114 ? 32.317 -2.565 -8.215 1.00 41.75 ? 114 MET A CA 1 ATOM 843 C C . MET A 1 114 ? 33.389 -1.615 -7.677 1.00 40.72 ? 114 MET A C 1 ATOM 844 O O . MET A 1 114 ? 34.537 -1.679 -8.118 1.00 41.18 ? 114 MET A O 1 ATOM 845 C CB . MET A 1 114 ? 32.341 -3.892 -7.441 1.00 41.87 ? 114 MET A CB 1 ATOM 846 C CG . MET A 1 114 ? 33.431 -4.873 -7.871 1.00 43.33 ? 114 MET A CG 1 ATOM 847 S SD . MET A 1 114 ? 33.575 -6.374 -6.863 1.00 45.07 ? 114 MET A SD 1 ATOM 848 C CE . MET A 1 114 ? 31.978 -6.434 -6.062 1.00 43.88 ? 114 MET A CE 1 ATOM 849 N N . PRO A 1 115 ? 33.029 -0.740 -6.710 1.00 39.22 ? 115 PRO A N 1 ATOM 850 C CA . PRO A 1 115 ? 34.026 0.181 -6.145 1.00 37.27 ? 115 PRO A CA 1 ATOM 851 C C . PRO A 1 115 ? 35.235 -0.568 -5.618 1.00 36.71 ? 115 PRO A C 1 ATOM 852 O O . PRO A 1 115 ? 35.105 -1.697 -5.164 1.00 38.25 ? 115 PRO A O 1 ATOM 853 C CB . PRO A 1 115 ? 33.297 0.849 -4.978 1.00 37.33 ? 115 PRO A CB 1 ATOM 854 C CG . PRO A 1 115 ? 31.905 0.382 -5.005 1.00 37.80 ? 115 PRO A CG 1 ATOM 855 C CD . PRO A 1 115 ? 31.689 -0.567 -6.122 1.00 37.83 ? 115 PRO A CD 1 ATOM 856 N N . ALA A 1 116 ? 36.406 0.051 -5.688 1.00 37.52 ? 116 ALA A N 1 ATOM 857 C CA . ALA A 1 116 ? 37.631 -0.544 -5.144 1.00 36.45 ? 116 ALA A CA 1 ATOM 858 C C . ALA A 1 116 ? 37.454 -0.878 -3.667 1.00 35.96 ? 116 ALA A C 1 ATOM 859 O O . ALA A 1 116 ? 37.870 -1.951 -3.221 1.00 34.92 ? 116 ALA A O 1 ATOM 860 C CB . ALA A 1 116 ? 38.802 0.406 -5.330 1.00 36.63 ? 116 ALA A CB 1 ATOM 861 N N . LEU A 1 117 ? 36.826 0.054 -2.936 1.00 35.01 ? 117 LEU A N 1 ATOM 862 C CA . LEU A 1 117 ? 36.568 -0.065 -1.502 1.00 35.97 ? 117 LEU A CA 1 ATOM 863 C C . LEU A 1 117 ? 35.081 -0.262 -1.214 1.00 35.71 ? 117 LEU A C 1 ATOM 864 O O . LEU A 1 117 ? 34.251 0.393 -1.817 1.00 36.76 ? 117 LEU A O 1 ATOM 865 C CB . LEU A 1 117 ? 37.092 1.172 -0.755 1.00 36.21 ? 117 LEU A CB 1 ATOM 866 C CG . LEU A 1 117 ? 38.597 1.465 -0.861 1.00 36.01 ? 117 LEU A CG 1 ATOM 867 C CD1 . LEU A 1 117 ? 38.894 2.852 -0.344 1.00 35.48 ? 117 LEU A CD1 1 ATOM 868 C CD2 . LEU A 1 117 ? 39.442 0.420 -0.118 1.00 36.28 ? 117 LEU A CD2 1 ATOM 869 N N . PRO A 1 118 ? 34.734 -1.181 -0.296 1.00 36.59 ? 118 PRO A N 1 ATOM 870 C CA . PRO A 1 118 ? 35.600 -2.061 0.493 1.00 35.49 ? 118 PRO A CA 1 ATOM 871 C C . PRO A 1 118 ? 36.009 -3.371 -0.197 1.00 34.83 ? 118 PRO A C 1 ATOM 872 O O . PRO A 1 118 ? 36.763 -4.161 0.374 1.00 35.85 ? 118 PRO A O 1 ATOM 873 C CB . PRO A 1 118 ? 34.749 -2.351 1.729 1.00 36.60 ? 118 PRO A CB 1 ATOM 874 C CG . PRO A 1 118 ? 33.328 -2.192 1.280 1.00 37.09 ? 118 PRO A CG 1 ATOM 875 C CD . PRO A 1 118 ? 33.308 -1.377 0.022 1.00 36.69 ? 118 PRO A CD 1 ATOM 876 N N . PHE A 1 119 ? 35.553 -3.579 -1.423 1.00 34.07 ? 119 PHE A N 1 ATOM 877 C CA . PHE A 1 119 ? 35.667 -4.888 -2.094 1.00 34.93 ? 119 PHE A CA 1 ATOM 878 C C . PHE A 1 119 ? 37.068 -5.474 -2.280 1.00 35.47 ? 119 PHE A C 1 ATOM 879 O O . PHE A 1 119 ? 37.240 -6.693 -2.269 1.00 35.07 ? 119 PHE A O 1 ATOM 880 C CB . PHE A 1 119 ? 34.868 -4.873 -3.400 1.00 33.46 ? 119 PHE A CB 1 ATOM 881 C CG . PHE A 1 119 ? 33.430 -4.493 -3.194 1.00 33.16 ? 119 PHE A CG 1 ATOM 882 C CD1 . PHE A 1 119 ? 32.519 -5.423 -2.710 1.00 33.33 ? 119 PHE A CD1 1 ATOM 883 C CD2 . PHE A 1 119 ? 33.001 -3.197 -3.413 1.00 33.00 ? 119 PHE A CD2 1 ATOM 884 C CE1 . PHE A 1 119 ? 31.196 -5.073 -2.484 1.00 33.50 ? 119 PHE A CE1 1 ATOM 885 C CE2 . PHE A 1 119 ? 31.679 -2.841 -3.183 1.00 33.07 ? 119 PHE A CE2 1 ATOM 886 C CZ . PHE A 1 119 ? 30.781 -3.782 -2.715 1.00 32.70 ? 119 PHE A CZ 1 ATOM 887 N N . MET A 1 120 ? 38.070 -4.617 -2.423 1.00 38.18 ? 120 MET A N 1 ATOM 888 C CA . MET A 1 120 ? 39.440 -5.098 -2.560 1.00 42.17 ? 120 MET A CA 1 ATOM 889 C C . MET A 1 120 ? 39.997 -5.601 -1.223 1.00 41.00 ? 120 MET A C 1 ATOM 890 O O . MET A 1 120 ? 41.026 -6.268 -1.195 1.00 42.62 ? 120 MET A O 1 ATOM 891 C CB . MET A 1 120 ? 40.350 -4.014 -3.159 1.00 43.53 ? 120 MET A CB 1 ATOM 892 C CG . MET A 1 120 ? 40.569 -2.826 -2.242 1.00 46.00 ? 120 MET A CG 1 ATOM 893 S SD . MET A 1 120 ? 41.746 -1.615 -2.833 1.00 48.51 ? 120 MET A SD 1 ATOM 894 C CE . MET A 1 120 ? 43.298 -2.511 -2.726 1.00 50.48 ? 120 MET A CE 1 ATOM 895 N N . LEU A 1 121 ? 39.314 -5.273 -0.126 1.00 40.41 ? 121 LEU A N 1 ATOM 896 C CA . LEU A 1 121 ? 39.734 -5.674 1.221 1.00 38.00 ? 121 LEU A CA 1 ATOM 897 C C . LEU A 1 121 ? 39.051 -6.963 1.685 1.00 36.88 ? 121 LEU A C 1 ATOM 898 O O . LEU A 1 121 ? 39.300 -7.461 2.792 1.00 37.30 ? 121 LEU A O 1 ATOM 899 C CB . LEU A 1 121 ? 39.458 -4.551 2.230 1.00 38.09 ? 121 LEU A CB 1 ATOM 900 C CG . LEU A 1 121 ? 40.224 -3.223 2.117 1.00 38.42 ? 121 LEU A CG 1 ATOM 901 C CD1 . LEU A 1 121 ? 39.684 -2.224 3.141 1.00 37.17 ? 121 LEU A CD1 1 ATOM 902 C CD2 . LEU A 1 121 ? 41.738 -3.406 2.263 1.00 37.65 ? 121 LEU A CD2 1 ATOM 903 N N . ALA A 1 122 ? 38.180 -7.500 0.845 1.00 33.22 ? 122 ALA A N 1 ATOM 904 C CA . ALA A 1 122 ? 37.546 -8.763 1.141 1.00 29.84 ? 122 ALA A CA 1 ATOM 905 C C . ALA A 1 122 ? 38.506 -9.914 0.829 1.00 29.15 ? 122 ALA A C 1 ATOM 906 O O . ALA A 1 122 ? 39.121 -9.929 -0.226 1.00 27.07 ? 122 ALA A O 1 ATOM 907 C CB . ALA A 1 122 ? 36.287 -8.885 0.340 1.00 28.36 ? 122 ALA A CB 1 ATOM 908 N N . GLU A 1 123 ? 38.625 -10.871 1.751 1.00 30.70 ? 123 GLU A N 1 ATOM 909 C CA . GLU A 1 123 ? 39.418 -12.096 1.530 1.00 31.46 ? 123 GLU A CA 1 ATOM 910 C C . GLU A 1 123 ? 38.610 -13.192 0.836 1.00 30.91 ? 123 GLU A C 1 ATOM 911 O O . GLU A 1 123 ? 39.133 -14.248 0.467 1.00 33.13 ? 123 GLU A O 1 ATOM 912 C CB . GLU A 1 123 ? 39.978 -12.625 2.858 1.00 33.78 ? 123 GLU A CB 1 ATOM 913 C CG . GLU A 1 123 ? 40.890 -11.643 3.588 1.00 37.26 ? 123 GLU A CG 1 ATOM 914 C CD . GLU A 1 123 ? 42.189 -11.394 2.842 1.00 40.62 ? 123 GLU A CD 1 ATOM 915 O OE1 . GLU A 1 123 ? 42.798 -12.384 2.368 1.00 42.38 ? 123 GLU A OE1 1 ATOM 916 O OE2 . GLU A 1 123 ? 42.596 -10.214 2.728 1.00 40.24 ? 123 GLU A OE2 1 ATOM 917 N N . PHE A 1 124 ? 37.321 -12.936 0.683 1.00 28.40 ? 124 PHE A N 1 ATOM 918 C CA . PHE A 1 124 ? 36.412 -13.843 0.033 1.00 26.90 ? 124 PHE A CA 1 ATOM 919 C C . PHE A 1 124 ? 36.064 -13.191 -1.316 1.00 28.36 ? 124 PHE A C 1 ATOM 920 O O . PHE A 1 124 ? 36.312 -11.985 -1.513 1.00 28.94 ? 124 PHE A O 1 ATOM 921 C CB . PHE A 1 124 ? 35.171 -14.009 0.919 1.00 24.63 ? 124 PHE A CB 1 ATOM 922 C CG . PHE A 1 124 ? 34.539 -12.699 1.299 1.00 25.19 ? 124 PHE A CG 1 ATOM 923 C CD1 . PHE A 1 124 ? 34.986 -11.993 2.412 1.00 22.24 ? 124 PHE A CD1 1 ATOM 924 C CD2 . PHE A 1 124 ? 33.530 -12.142 0.509 1.00 25.15 ? 124 PHE A CD2 1 ATOM 925 C CE1 . PHE A 1 124 ? 34.435 -10.781 2.746 1.00 21.92 ? 124 PHE A CE1 1 ATOM 926 C CE2 . PHE A 1 124 ? 32.965 -10.909 0.841 1.00 23.77 ? 124 PHE A CE2 1 ATOM 927 C CZ . PHE A 1 124 ? 33.417 -10.230 1.960 1.00 23.43 ? 124 PHE A CZ 1 ATOM 928 N N . ASP A 1 125 ? 35.472 -13.979 -2.213 1.00 27.17 ? 125 ASP A N 1 ATOM 929 C CA . ASP A 1 125 ? 35.197 -13.580 -3.591 1.00 28.58 ? 125 ASP A CA 1 ATOM 930 C C . ASP A 1 125 ? 33.782 -13.050 -3.810 1.00 30.16 ? 125 ASP A C 1 ATOM 931 O O . ASP A 1 125 ? 33.574 -12.182 -4.638 1.00 29.56 ? 125 ASP A O 1 ATOM 932 C CB . ASP A 1 125 ? 35.444 -14.760 -4.548 1.00 27.87 ? 125 ASP A CB 1 ATOM 933 C CG . ASP A 1 125 ? 36.784 -15.431 -4.314 1.00 28.66 ? 125 ASP A CG 1 ATOM 934 O OD1 . ASP A 1 125 ? 37.821 -14.762 -4.502 1.00 30.57 ? 125 ASP A OD1 1 ATOM 935 O OD2 . ASP A 1 125 ? 36.805 -16.622 -3.928 1.00 27.97 ? 125 ASP A OD2 1 ATOM 936 N N . GLY A 1 126 ? 32.803 -13.592 -3.093 1.00 31.69 ? 126 GLY A N 1 ATOM 937 C CA . GLY A 1 126 ? 31.427 -13.141 -3.270 1.00 30.25 ? 126 GLY A CA 1 ATOM 938 C C . GLY A 1 126 ? 30.564 -13.231 -2.032 1.00 28.88 ? 126 GLY A C 1 ATOM 939 O O . GLY A 1 126 ? 31.074 -13.398 -0.920 1.00 26.19 ? 126 GLY A O 1 ATOM 940 N N . VAL A 1 127 ? 29.254 -13.108 -2.248 1.00 27.63 ? 127 VAL A N 1 ATOM 941 C CA . VAL A 1 127 ? 28.250 -13.211 -1.189 1.00 28.44 ? 127 VAL A CA 1 ATOM 942 C C . VAL A 1 127 ? 27.083 -14.120 -1.569 1.00 27.43 ? 127 VAL A C 1 ATOM 943 O O . VAL A 1 127 ? 26.602 -14.112 -2.704 1.00 26.41 ? 127 VAL A O 1 ATOM 944 C CB . VAL A 1 127 ? 27.712 -11.807 -0.735 1.00 29.94 ? 127 VAL A CB 1 ATOM 945 C CG1 . VAL A 1 127 ? 27.243 -10.976 -1.912 1.00 28.71 ? 127 VAL A CG1 1 ATOM 946 C CG2 . VAL A 1 127 ? 26.587 -11.951 0.289 1.00 29.77 ? 127 VAL A CG2 1 ATOM 947 N N . VAL A 1 128 ? 26.645 -14.908 -0.595 1.00 27.59 ? 128 VAL A N 1 ATOM 948 C CA . VAL A 1 128 ? 25.409 -15.663 -0.691 1.00 26.43 ? 128 VAL A CA 1 ATOM 949 C C . VAL A 1 128 ? 24.412 -14.992 0.260 1.00 29.04 ? 128 VAL A C 1 ATOM 950 O O . VAL A 1 128 ? 24.575 -15.029 1.487 1.00 30.81 ? 128 VAL A O 1 ATOM 951 C CB . VAL A 1 128 ? 25.634 -17.158 -0.353 1.00 25.35 ? 128 VAL A CB 1 ATOM 952 C CG1 . VAL A 1 128 ? 24.307 -17.887 -0.149 1.00 23.85 ? 128 VAL A CG1 1 ATOM 953 C CG2 . VAL A 1 128 ? 26.457 -17.836 -1.451 1.00 23.48 ? 128 VAL A CG2 1 ATOM 954 N N . GLY A 1 129 ? 23.403 -14.340 -0.314 1.00 29.57 ? 129 GLY A N 1 ATOM 955 C CA . GLY A 1 129 ? 22.370 -13.679 0.482 1.00 29.53 ? 129 GLY A CA 1 ATOM 956 C C . GLY A 1 129 ? 21.448 -14.711 1.103 1.00 29.28 ? 129 GLY A C 1 ATOM 957 O O . GLY A 1 129 ? 21.028 -15.660 0.437 1.00 28.17 ? 129 GLY A O 1 ATOM 958 N N . MET A 1 130 ? 21.138 -14.547 2.384 1.00 27.75 ? 130 MET A N 1 ATOM 959 C CA . MET A 1 130 ? 20.289 -15.529 3.052 1.00 27.58 ? 130 MET A CA 1 ATOM 960 C C . MET A 1 130 ? 19.003 -14.891 3.527 1.00 28.08 ? 130 MET A C 1 ATOM 961 O O . MET A 1 130 ? 18.270 -15.475 4.328 1.00 27.57 ? 130 MET A O 1 ATOM 962 C CB . MET A 1 130 ? 21.025 -16.191 4.213 1.00 28.34 ? 130 MET A CB 1 ATOM 963 C CG . MET A 1 130 ? 22.327 -16.859 3.830 1.00 28.61 ? 130 MET A CG 1 ATOM 964 S SD . MET A 1 130 ? 22.121 -18.440 2.994 1.00 29.18 ? 130 MET A SD 1 ATOM 965 C CE . MET A 1 130 ? 21.630 -19.467 4.381 1.00 31.35 ? 130 MET A CE 1 ATOM 966 N N . GLY A 1 131 ? 18.750 -13.680 3.029 1.00 29.29 ? 131 GLY A N 1 ATOM 967 C CA . GLY A 1 131 ? 17.531 -12.948 3.323 1.00 31.03 ? 131 GLY A CA 1 ATOM 968 C C . GLY A 1 131 ? 16.419 -13.319 2.352 1.00 32.50 ? 131 GLY A C 1 ATOM 969 O O . GLY A 1 131 ? 16.561 -14.257 1.572 1.00 30.23 ? 131 GLY A O 1 ATOM 970 N N . PHE A 1 132 ? 15.332 -12.549 2.392 1.00 32.91 ? 132 PHE A N 1 ATOM 971 C CA . PHE A 1 132 ? 14.060 -12.913 1.768 1.00 33.56 ? 132 PHE A CA 1 ATOM 972 C C . PHE A 1 132 ? 13.933 -12.329 0.368 1.00 34.56 ? 132 PHE A C 1 ATOM 973 O O . PHE A 1 132 ? 14.530 -11.296 0.057 1.00 35.09 ? 132 PHE A O 1 ATOM 974 C CB . PHE A 1 132 ? 12.879 -12.402 2.620 1.00 32.73 ? 132 PHE A CB 1 ATOM 975 C CG . PHE A 1 132 ? 12.809 -12.991 4.016 1.00 32.25 ? 132 PHE A CG 1 ATOM 976 C CD1 . PHE A 1 132 ? 13.596 -12.481 5.054 1.00 31.89 ? 132 PHE A CD1 1 ATOM 977 C CD2 . PHE A 1 132 ? 11.929 -14.026 4.300 1.00 31.81 ? 132 PHE A CD2 1 ATOM 978 C CE1 . PHE A 1 132 ? 13.519 -13.013 6.336 1.00 31.68 ? 132 PHE A CE1 1 ATOM 979 C CE2 . PHE A 1 132 ? 11.843 -14.563 5.583 1.00 32.18 ? 132 PHE A CE2 1 ATOM 980 C CZ . PHE A 1 132 ? 12.641 -14.064 6.600 1.00 32.13 ? 132 PHE A CZ 1 ATOM 981 N N . ILE A 1 133 ? 13.118 -12.978 -0.456 1.00 35.74 ? 133 ILE A N 1 ATOM 982 C CA . ILE A 1 133 ? 12.828 -12.511 -1.811 1.00 37.63 ? 133 ILE A CA 1 ATOM 983 C C . ILE A 1 133 ? 12.388 -11.040 -1.873 1.00 37.89 ? 133 ILE A C 1 ATOM 984 O O . ILE A 1 133 ? 12.680 -10.343 -2.848 1.00 36.90 ? 133 ILE A O 1 ATOM 985 C CB . ILE A 1 133 ? 11.814 -13.445 -2.532 1.00 37.98 ? 133 ILE A CB 1 ATOM 986 C CG1 . ILE A 1 133 ? 11.854 -13.219 -4.050 1.00 38.65 ? 133 ILE A CG1 1 ATOM 987 C CG2 . ILE A 1 133 ? 10.411 -13.322 -1.935 1.00 38.13 ? 133 ILE A CG2 1 ATOM 988 C CD1 . ILE A 1 133 ? 11.216 -14.343 -4.861 1.00 38.21 ? 133 ILE A CD1 1 ATOM 989 N N . GLU A 1 134 ? 11.729 -10.573 -0.812 1.00 39.15 ? 134 GLU A N 1 ATOM 990 C CA . GLU A 1 134 ? 11.276 -9.183 -0.705 1.00 40.84 ? 134 GLU A CA 1 ATOM 991 C C . GLU A 1 134 ? 12.399 -8.162 -0.893 1.00 41.09 ? 134 GLU A C 1 ATOM 992 O O . GLU A 1 134 ? 12.170 -7.077 -1.422 1.00 39.24 ? 134 GLU A O 1 ATOM 993 C CB . GLU A 1 134 ? 10.572 -8.946 0.631 1.00 42.16 ? 134 GLU A CB 1 ATOM 994 C CG . GLU A 1 134 ? 9.140 -9.472 0.699 1.00 43.81 ? 134 GLU A CG 1 ATOM 995 C CD . GLU A 1 134 ? 9.039 -10.905 1.189 1.00 45.76 ? 134 GLU A CD 1 ATOM 996 O OE1 . GLU A 1 134 ? 9.993 -11.686 1.010 1.00 47.68 ? 134 GLU A OE1 1 ATOM 997 O OE2 . GLU A 1 134 ? 7.988 -11.264 1.756 1.00 47.99 ? 134 GLU A OE2 1 ATOM 998 N N . GLN A 1 135 ? 13.609 -8.520 -0.465 1.00 42.47 ? 135 GLN A N 1 ATOM 999 C CA . GLN A 1 135 ? 14.759 -7.613 -0.528 1.00 43.10 ? 135 GLN A CA 1 ATOM 1000 C C . GLN A 1 135 ? 15.743 -7.995 -1.631 1.00 42.30 ? 135 GLN A C 1 ATOM 1001 O O . GLN A 1 135 ? 16.820 -7.401 -1.741 1.00 41.62 ? 135 GLN A O 1 ATOM 1002 C CB . GLN A 1 135 ? 15.483 -7.589 0.814 1.00 46.36 ? 135 GLN A CB 1 ATOM 1003 C CG . GLN A 1 135 ? 14.563 -7.466 2.011 1.00 50.00 ? 135 GLN A CG 1 ATOM 1004 C CD . GLN A 1 135 ? 14.350 -6.034 2.435 1.00 52.18 ? 135 GLN A CD 1 ATOM 1005 O OE1 . GLN A 1 135 ? 15.292 -5.359 2.863 1.00 53.85 ? 135 GLN A OE1 1 ATOM 1006 N NE2 . GLN A 1 135 ? 13.106 -5.560 2.339 1.00 52.64 ? 135 GLN A NE2 1 ATOM 1007 N N . ALA A 1 136 ? 15.363 -8.986 -2.437 1.00 40.67 ? 136 ALA A N 1 ATOM 1008 C CA . ALA A 1 136 ? 16.171 -9.452 -3.554 1.00 39.25 ? 136 ALA A CA 1 ATOM 1009 C C . ALA A 1 136 ? 16.090 -8.477 -4.716 1.00 39.67 ? 136 ALA A C 1 ATOM 1010 O O . ALA A 1 136 ? 14.999 -8.098 -5.152 1.00 40.78 ? 136 ALA A O 1 ATOM 1011 C CB . ALA A 1 136 ? 15.714 -10.844 -3.988 1.00 39.04 ? 136 ALA A CB 1 ATOM 1012 N N . ILE A 1 137 ? 17.249 -8.058 -5.207 1.00 39.16 ? 137 ILE A N 1 ATOM 1013 C CA . ILE A 1 137 ? 17.316 -7.210 -6.389 1.00 39.59 ? 137 ILE A CA 1 ATOM 1014 C C . ILE A 1 137 ? 16.876 -8.030 -7.605 1.00 40.31 ? 137 ILE A C 1 ATOM 1015 O O . ILE A 1 137 ? 17.424 -9.102 -7.861 1.00 39.98 ? 137 ILE A O 1 ATOM 1016 C CB . ILE A 1 137 ? 18.742 -6.640 -6.583 1.00 40.00 ? 137 ILE A CB 1 ATOM 1017 C CG1 . ILE A 1 137 ? 19.186 -5.900 -5.309 1.00 41.05 ? 137 ILE A CG1 1 ATOM 1018 C CG2 . ILE A 1 137 ? 18.810 -5.719 -7.803 1.00 39.50 ? 137 ILE A CG2 1 ATOM 1019 C CD1 . ILE A 1 137 ? 20.557 -5.271 -5.398 1.00 40.45 ? 137 ILE A CD1 1 ATOM 1020 N N . GLY A 1 138 ? 15.867 -7.523 -8.317 1.00 41.33 ? 138 GLY A N 1 ATOM 1021 C CA . GLY A 1 138 ? 15.265 -8.184 -9.477 1.00 40.99 ? 138 GLY A CA 1 ATOM 1022 C C . GLY A 1 138 ? 14.270 -9.271 -9.103 1.00 42.12 ? 138 GLY A C 1 ATOM 1023 O O . GLY A 1 138 ? 13.908 -10.105 -9.940 1.00 44.10 ? 138 GLY A O 1 ATOM 1024 N N . ARG A 1 139 ? 13.828 -9.251 -7.848 1.00 41.69 ? 139 ARG A N 1 ATOM 1025 C CA . ARG A 1 139 ? 13.071 -10.343 -7.229 1.00 44.58 ? 139 ARG A CA 1 ATOM 1026 C C . ARG A 1 139 ? 13.548 -11.743 -7.680 1.00 42.13 ? 139 ARG A C 1 ATOM 1027 O O . ARG A 1 139 ? 12.748 -12.639 -7.967 1.00 42.21 ? 139 ARG A O 1 ATOM 1028 C CB . ARG A 1 139 ? 11.555 -10.148 -7.397 1.00 47.08 ? 139 ARG A CB 1 ATOM 1029 C CG . ARG A 1 139 ? 10.726 -10.757 -6.249 1.00 49.74 ? 139 ARG A CG 1 ATOM 1030 C CD . ARG A 1 139 ? 9.206 -10.611 -6.454 1.00 50.45 ? 139 ARG A CD 1 ATOM 1031 N NE . ARG A 1 139 ? 8.440 -10.681 -5.198 1.00 54.21 ? 139 ARG A NE 1 ATOM 1032 C CZ . ARG A 1 139 ? 8.466 -9.748 -4.238 1.00 55.12 ? 139 ARG A CZ 1 ATOM 1033 N NH1 . ARG A 1 139 ? 9.243 -8.669 -4.355 1.00 55.46 ? 139 ARG A NH1 1 ATOM 1034 N NH2 . ARG A 1 139 ? 7.725 -9.897 -3.146 1.00 54.41 ? 139 ARG A NH2 1 ATOM 1035 N N . VAL A 1 140 ? 14.868 -11.900 -7.740 1.00 38.88 ? 140 VAL A N 1 ATOM 1036 C CA . VAL A 1 140 ? 15.515 -13.183 -7.997 1.00 36.54 ? 140 VAL A CA 1 ATOM 1037 C C . VAL A 1 140 ? 15.315 -14.100 -6.780 1.00 35.55 ? 140 VAL A C 1 ATOM 1038 O O . VAL A 1 140 ? 15.572 -13.699 -5.642 1.00 37.18 ? 140 VAL A O 1 ATOM 1039 C CB . VAL A 1 140 ? 17.032 -12.979 -8.274 1.00 34.95 ? 140 VAL A CB 1 ATOM 1040 C CG1 . VAL A 1 140 ? 17.725 -14.285 -8.558 1.00 32.25 ? 140 VAL A CG1 1 ATOM 1041 C CG2 . VAL A 1 140 ? 17.237 -12.010 -9.421 1.00 34.23 ? 140 VAL A CG2 1 ATOM 1042 N N . THR A 1 141 ? 14.842 -15.318 -7.021 1.00 33.21 ? 141 THR A N 1 ATOM 1043 C CA . THR A 1 141 ? 14.599 -16.268 -5.948 1.00 33.47 ? 141 THR A CA 1 ATOM 1044 C C . THR A 1 141 ? 15.887 -16.556 -5.180 1.00 33.65 ? 141 THR A C 1 ATOM 1045 O O . THR A 1 141 ? 16.873 -17.033 -5.766 1.00 33.58 ? 141 THR A O 1 ATOM 1046 C CB . THR A 1 141 ? 13.985 -17.588 -6.473 1.00 33.11 ? 141 THR A CB 1 ATOM 1047 O OG1 . THR A 1 141 ? 12.795 -17.288 -7.202 1.00 33.93 ? 141 THR A OG1 1 ATOM 1048 C CG2 . THR A 1 141 ? 13.637 -18.522 -5.314 1.00 29.14 ? 141 THR A CG2 1 ATOM 1049 N N . PRO A 1 142 ? 15.888 -16.241 -3.868 1.00 34.04 ? 142 PRO A N 1 ATOM 1050 C CA . PRO A 1 142 ? 17.064 -16.456 -3.031 1.00 32.20 ? 142 PRO A CA 1 ATOM 1051 C C . PRO A 1 142 ? 17.394 -17.923 -2.931 1.00 29.64 ? 142 PRO A C 1 ATOM 1052 O O . PRO A 1 142 ? 16.496 -18.766 -3.017 1.00 30.04 ? 142 PRO A O 1 ATOM 1053 C CB . PRO A 1 142 ? 16.632 -15.907 -1.669 1.00 32.44 ? 142 PRO A CB 1 ATOM 1054 C CG . PRO A 1 142 ? 15.553 -14.943 -1.997 1.00 33.86 ? 142 PRO A CG 1 ATOM 1055 C CD . PRO A 1 142 ? 14.798 -15.621 -3.095 1.00 32.77 ? 142 PRO A CD 1 ATOM 1056 N N . ILE A 1 143 ? 18.677 -18.214 -2.746 1.00 27.56 ? 143 ILE A N 1 ATOM 1057 C CA . ILE A 1 143 ? 19.164 -19.588 -2.692 1.00 26.70 ? 143 ILE A CA 1 ATOM 1058 C C . ILE A 1 143 ? 18.451 -20.444 -1.640 1.00 27.45 ? 143 ILE A C 1 ATOM 1059 O O . ILE A 1 143 ? 18.143 -21.597 -1.906 1.00 29.22 ? 143 ILE A O 1 ATOM 1060 C CB . ILE A 1 143 ? 20.722 -19.653 -2.540 1.00 25.65 ? 143 ILE A CB 1 ATOM 1061 C CG1 . ILE A 1 143 ? 21.256 -21.029 -2.961 1.00 26.41 ? 143 ILE A CG1 1 ATOM 1062 C CG2 . ILE A 1 143 ? 21.170 -19.226 -1.136 1.00 24.98 ? 143 ILE A CG2 1 ATOM 1063 C CD1 . ILE A 1 143 ? 22.781 -21.127 -3.043 1.00 26.10 ? 143 ILE A CD1 1 ATOM 1064 N N . PHE A 1 144 ? 18.164 -19.890 -0.463 1.00 28.12 ? 144 PHE A N 1 ATOM 1065 C CA . PHE A 1 144 ? 17.585 -20.719 0.581 1.00 28.82 ? 144 PHE A CA 1 ATOM 1066 C C . PHE A 1 144 ? 16.144 -21.073 0.278 1.00 30.85 ? 144 PHE A C 1 ATOM 1067 O O . PHE A 1 144 ? 15.652 -22.094 0.754 1.00 31.15 ? 144 PHE A O 1 ATOM 1068 C CB . PHE A 1 144 ? 17.739 -20.138 1.997 1.00 27.40 ? 144 PHE A CB 1 ATOM 1069 C CG . PHE A 1 144 ? 17.574 -21.181 3.079 1.00 26.91 ? 144 PHE A CG 1 ATOM 1070 C CD1 . PHE A 1 144 ? 18.482 -22.242 3.183 1.00 25.74 ? 144 PHE A CD1 1 ATOM 1071 C CD2 . PHE A 1 144 ? 16.490 -21.138 3.949 1.00 26.22 ? 144 PHE A CD2 1 ATOM 1072 C CE1 . PHE A 1 144 ? 18.333 -23.224 4.165 1.00 26.12 ? 144 PHE A CE1 1 ATOM 1073 C CE2 . PHE A 1 144 ? 16.318 -22.121 4.941 1.00 26.97 ? 144 PHE A CE2 1 ATOM 1074 C CZ . PHE A 1 144 ? 17.241 -23.159 5.059 1.00 26.74 ? 144 PHE A CZ 1 ATOM 1075 N N . ASP A 1 145 ? 15.485 -20.241 -0.526 1.00 32.89 ? 145 ASP A N 1 ATOM 1076 C CA . ASP A 1 145 ? 14.144 -20.544 -1.025 1.00 36.29 ? 145 ASP A CA 1 ATOM 1077 C C . ASP A 1 145 ? 14.149 -21.679 -2.045 1.00 36.05 ? 145 ASP A C 1 ATOM 1078 O O . ASP A 1 145 ? 13.211 -22.464 -2.104 1.00 37.19 ? 145 ASP A O 1 ATOM 1079 C CB . ASP A 1 145 ? 13.504 -19.296 -1.624 1.00 39.80 ? 145 ASP A CB 1 ATOM 1080 C CG . ASP A 1 145 ? 13.263 -18.221 -0.590 1.00 43.38 ? 145 ASP A CG 1 ATOM 1081 O OD1 . ASP A 1 145 ? 14.219 -17.840 0.126 1.00 44.96 ? 145 ASP A OD1 1 ATOM 1082 O OD2 . ASP A 1 145 ? 12.110 -17.760 -0.489 1.00 45.58 ? 145 ASP A OD2 1 ATOM 1083 N N . ASN A 1 146 ? 15.207 -21.762 -2.847 1.00 36.38 ? 146 ASN A N 1 ATOM 1084 C CA . ASN A 1 146 ? 15.367 -22.862 -3.787 1.00 34.07 ? 146 ASN A CA 1 ATOM 1085 C C . ASN A 1 146 ? 15.767 -24.129 -3.074 1.00 35.28 ? 146 ASN A C 1 ATOM 1086 O O . ASN A 1 146 ? 15.452 -25.225 -3.531 1.00 35.96 ? 146 ASN A O 1 ATOM 1087 C CB . ASN A 1 146 ? 16.380 -22.514 -4.881 1.00 33.24 ? 146 ASN A CB 1 ATOM 1088 C CG . ASN A 1 146 ? 15.804 -21.592 -5.929 1.00 31.20 ? 146 ASN A CG 1 ATOM 1089 O OD1 . ASN A 1 146 ? 14.601 -21.608 -6.183 1.00 29.22 ? 146 ASN A OD1 1 ATOM 1090 N ND2 . ASN A 1 146 ? 16.659 -20.776 -6.542 1.00 30.88 ? 146 ASN A ND2 1 ATOM 1091 N N . ILE A 1 147 ? 16.455 -23.996 -1.943 1.00 35.93 ? 147 ILE A N 1 ATOM 1092 C CA . ILE A 1 147 ? 16.748 -25.185 -1.139 1.00 35.07 ? 147 ILE A CA 1 ATOM 1093 C C . ILE A 1 147 ? 15.487 -25.708 -0.437 1.00 36.16 ? 147 ILE A C 1 ATOM 1094 O O . ILE A 1 147 ? 15.232 -26.912 -0.444 1.00 37.94 ? 147 ILE A O 1 ATOM 1095 C CB . ILE A 1 147 ? 17.919 -24.992 -0.158 1.00 33.60 ? 147 ILE A CB 1 ATOM 1096 C CG1 . ILE A 1 147 ? 19.211 -24.724 -0.935 1.00 34.04 ? 147 ILE A CG1 1 ATOM 1097 C CG2 . ILE A 1 147 ? 18.092 -26.242 0.703 1.00 31.07 ? 147 ILE A CG2 1 ATOM 1098 C CD1 . ILE A 1 147 ? 20.429 -24.395 -0.071 1.00 33.62 ? 147 ILE A CD1 1 ATOM 1099 N N . ILE A 1 148 ? 14.703 -24.809 0.152 1.00 35.65 ? 148 ILE A N 1 ATOM 1100 C CA . ILE A 1 148 ? 13.421 -25.184 0.746 1.00 37.10 ? 148 ILE A CA 1 ATOM 1101 C C . ILE A 1 148 ? 12.544 -25.961 -0.273 1.00 37.32 ? 148 ILE A C 1 ATOM 1102 O O . ILE A 1 148 ? 12.111 -27.078 0.013 1.00 35.82 ? 148 ILE A O 1 ATOM 1103 C CB . ILE A 1 148 ? 12.675 -23.949 1.328 1.00 36.98 ? 148 ILE A CB 1 ATOM 1104 C CG1 . ILE A 1 148 ? 13.449 -23.367 2.518 1.00 37.44 ? 148 ILE A CG1 1 ATOM 1105 C CG2 . ILE A 1 148 ? 11.248 -24.314 1.747 1.00 36.10 ? 148 ILE A CG2 1 ATOM 1106 C CD1 . ILE A 1 148 ? 13.068 -21.928 2.872 1.00 37.05 ? 148 ILE A CD1 1 ATOM 1107 N N . SER A 1 149 ? 12.329 -25.374 -1.456 1.00 37.35 ? 149 SER A N 1 ATOM 1108 C CA . SER A 1 149 ? 11.584 -26.011 -2.571 1.00 39.92 ? 149 SER A CA 1 ATOM 1109 C C . SER A 1 149 ? 11.992 -27.452 -2.914 1.00 39.58 ? 149 SER A C 1 ATOM 1110 O O . SER A 1 149 ? 11.180 -28.206 -3.439 1.00 40.48 ? 149 SER A O 1 ATOM 1111 C CB . SER A 1 149 ? 11.706 -25.173 -3.853 1.00 40.81 ? 149 SER A CB 1 ATOM 1112 O OG . SER A 1 149 ? 11.319 -23.830 -3.639 1.00 42.93 ? 149 SER A OG 1 ATOM 1113 N N . GLN A 1 150 ? 13.250 -27.808 -2.654 1.00 39.43 ? 150 GLN A N 1 ATOM 1114 C CA . GLN A 1 150 ? 13.761 -29.161 -2.895 1.00 40.08 ? 150 GLN A CA 1 ATOM 1115 C C . GLN A 1 150 ? 13.215 -30.178 -1.903 1.00 41.30 ? 150 GLN A C 1 ATOM 1116 O O . GLN A 1 150 ? 13.177 -31.372 -2.197 1.00 40.74 ? 150 GLN A O 1 ATOM 1117 C CB . GLN A 1 150 ? 15.289 -29.190 -2.832 1.00 39.37 ? 150 GLN A CB 1 ATOM 1118 C CG . GLN A 1 150 ? 15.968 -28.535 -4.007 1.00 40.13 ? 150 GLN A CG 1 ATOM 1119 C CD . GLN A 1 150 ? 17.421 -28.931 -4.147 1.00 40.93 ? 150 GLN A CD 1 ATOM 1120 O OE1 . GLN A 1 150 ? 17.978 -29.634 -3.304 1.00 42.14 ? 150 GLN A OE1 1 ATOM 1121 N NE2 . GLN A 1 150 ? 18.046 -28.481 -5.224 1.00 41.08 ? 150 GLN A NE2 1 ATOM 1122 N N . GLY A 1 151 ? 12.813 -29.699 -0.727 1.00 42.81 ? 151 GLY A N 1 ATOM 1123 C CA . GLY A 1 151 ? 12.329 -30.559 0.353 1.00 44.40 ? 151 GLY A CA 1 ATOM 1124 C C . GLY A 1 151 ? 13.316 -31.622 0.812 1.00 46.35 ? 151 GLY A C 1 ATOM 1125 O O . GLY A 1 151 ? 12.917 -32.754 1.094 1.00 47.22 ? 151 GLY A O 1 ATOM 1126 N N . VAL A 1 152 ? 14.600 -31.262 0.880 1.00 46.28 ? 152 VAL A N 1 ATOM 1127 C CA . VAL A 1 152 ? 15.649 -32.164 1.390 1.00 46.23 ? 152 VAL A CA 1 ATOM 1128 C C . VAL A 1 152 ? 16.063 -31.895 2.851 1.00 45.66 ? 152 VAL A C 1 ATOM 1129 O O . VAL A 1 152 ? 16.644 -32.768 3.515 1.00 45.44 ? 152 VAL A O 1 ATOM 1130 C CB . VAL A 1 152 ? 16.919 -32.148 0.502 1.00 47.10 ? 152 VAL A CB 1 ATOM 1131 C CG1 . VAL A 1 152 ? 16.695 -32.977 -0.752 1.00 48.43 ? 152 VAL A CG1 1 ATOM 1132 C CG2 . VAL A 1 152 ? 17.350 -30.708 0.162 1.00 46.84 ? 152 VAL A CG2 1 ATOM 1133 N N . LEU A 1 153 ? 15.760 -30.694 3.342 1.00 43.45 ? 153 LEU A N 1 ATOM 1134 C CA . LEU A 1 153 ? 16.155 -30.283 4.695 1.00 42.50 ? 153 LEU A CA 1 ATOM 1135 C C . LEU A 1 153 ? 15.320 -30.944 5.796 1.00 41.63 ? 153 LEU A C 1 ATOM 1136 O O . LEU A 1 153 ? 14.118 -31.153 5.638 1.00 39.43 ? 153 LEU A O 1 ATOM 1137 C CB . LEU A 1 153 ? 16.066 -28.759 4.840 1.00 40.83 ? 153 LEU A CB 1 ATOM 1138 C CG . LEU A 1 153 ? 16.830 -27.851 3.869 1.00 39.74 ? 153 LEU A CG 1 ATOM 1139 C CD1 . LEU A 1 153 ? 16.390 -26.425 4.087 1.00 40.20 ? 153 LEU A CD1 1 ATOM 1140 C CD2 . LEU A 1 153 ? 18.350 -27.976 4.007 1.00 38.70 ? 153 LEU A CD2 1 ATOM 1141 N N . LYS A 1 154 ? 15.981 -31.267 6.904 1.00 42.27 ? 154 LYS A N 1 ATOM 1142 C CA . LYS A 1 154 ? 15.322 -31.714 8.124 1.00 43.72 ? 154 LYS A CA 1 ATOM 1143 C C . LYS A 1 154 ? 14.383 -30.613 8.642 1.00 43.18 ? 154 LYS A C 1 ATOM 1144 O O . LYS A 1 154 ? 13.221 -30.873 8.943 1.00 43.41 ? 154 LYS A O 1 ATOM 1145 C CB . LYS A 1 154 ? 16.383 -32.076 9.166 1.00 45.04 ? 154 LYS A CB 1 ATOM 1146 C CG . LYS A 1 154 ? 15.893 -32.818 10.410 1.00 46.62 ? 154 LYS A CG 1 ATOM 1147 C CD . LYS A 1 154 ? 17.097 -33.231 11.275 1.00 47.54 ? 154 LYS A CD 1 ATOM 1148 C CE . LYS A 1 154 ? 16.708 -34.129 12.461 1.00 50.33 ? 154 LYS A CE 1 ATOM 1149 N NZ . LYS A 1 154 ? 15.922 -33.407 13.501 1.00 51.76 ? 154 LYS A NZ 1 ATOM 1150 N N . GLU A 1 155 ? 14.884 -29.382 8.722 1.00 42.85 ? 155 GLU A N 1 ATOM 1151 C CA . GLU A 1 155 ? 14.066 -28.238 9.120 1.00 44.06 ? 155 GLU A CA 1 ATOM 1152 C C . GLU A 1 155 ? 14.356 -27.051 8.205 1.00 41.17 ? 155 GLU A C 1 ATOM 1153 O O . GLU A 1 155 ? 15.459 -26.945 7.671 1.00 41.07 ? 155 GLU A O 1 ATOM 1154 C CB . GLU A 1 155 ? 14.336 -27.869 10.583 1.00 45.24 ? 155 GLU A CB 1 ATOM 1155 C CG . GLU A 1 155 ? 13.791 -28.861 11.618 1.00 47.80 ? 155 GLU A CG 1 ATOM 1156 C CD . GLU A 1 155 ? 14.400 -28.689 13.024 1.00 49.52 ? 155 GLU A CD 1 ATOM 1157 O OE1 . GLU A 1 155 ? 15.110 -27.684 13.282 1.00 50.70 ? 155 GLU A OE1 1 ATOM 1158 O OE2 . GLU A 1 155 ? 14.165 -29.577 13.881 1.00 51.92 ? 155 GLU A OE2 1 ATOM 1159 N N . ASP A 1 156 ? 13.371 -26.169 8.018 1.00 38.73 ? 156 ASP A N 1 ATOM 1160 C CA . ASP A 1 156 ? 13.555 -24.945 7.220 1.00 36.57 ? 156 ASP A CA 1 ATOM 1161 C C . ASP A 1 156 ? 14.256 -23.858 8.051 1.00 35.12 ? 156 ASP A C 1 ATOM 1162 O O . ASP A 1 156 ? 13.707 -22.774 8.309 1.00 34.11 ? 156 ASP A O 1 ATOM 1163 C CB . ASP A 1 156 ? 12.224 -24.428 6.677 1.00 37.66 ? 156 ASP A CB 1 ATOM 1164 C CG . ASP A 1 156 ? 11.599 -25.350 5.618 1.00 40.24 ? 156 ASP A CG 1 ATOM 1165 O OD1 . ASP A 1 156 ? 12.255 -26.305 5.126 1.00 41.35 ? 156 ASP A OD1 1 ATOM 1166 O OD2 . ASP A 1 156 ? 10.423 -25.100 5.276 1.00 40.54 ? 156 ASP A OD2 1 ATOM 1167 N N . VAL A 1 157 ? 15.469 -24.182 8.487 1.00 31.99 ? 157 VAL A N 1 ATOM 1168 C CA . VAL A 1 157 ? 16.272 -23.298 9.324 1.00 30.86 ? 157 VAL A CA 1 ATOM 1169 C C . VAL A 1 157 ? 17.710 -23.372 8.868 1.00 28.79 ? 157 VAL A C 1 ATOM 1170 O O . VAL A 1 157 ? 18.103 -24.310 8.192 1.00 29.37 ? 157 VAL A O 1 ATOM 1171 C CB . VAL A 1 157 ? 16.223 -23.698 10.833 1.00 31.07 ? 157 VAL A CB 1 ATOM 1172 C CG1 . VAL A 1 157 ? 14.792 -23.652 11.371 1.00 31.02 ? 157 VAL A CG1 1 ATOM 1173 C CG2 . VAL A 1 157 ? 16.844 -25.091 11.060 1.00 30.45 ? 157 VAL A CG2 1 ATOM 1174 N N . PHE A 1 158 ? 18.485 -22.365 9.231 1.00 28.57 ? 158 PHE A N 1 ATOM 1175 C CA . PHE A 1 158 ? 19.931 -22.421 9.107 1.00 27.70 ? 158 PHE A CA 1 ATOM 1176 C C . PHE A 1 158 ? 20.520 -21.675 10.291 1.00 27.74 ? 158 PHE A C 1 ATOM 1177 O O . PHE A 1 158 ? 19.898 -20.757 10.832 1.00 27.90 ? 158 PHE A O 1 ATOM 1178 C CB . PHE A 1 158 ? 20.416 -21.845 7.767 1.00 26.51 ? 158 PHE A CB 1 ATOM 1179 C CG . PHE A 1 158 ? 19.958 -20.447 7.500 1.00 26.48 ? 158 PHE A CG 1 ATOM 1180 C CD1 . PHE A 1 158 ? 20.704 -19.363 7.943 1.00 27.01 ? 158 PHE A CD1 1 ATOM 1181 C CD2 . PHE A 1 158 ? 18.767 -20.209 6.822 1.00 27.63 ? 158 PHE A CD2 1 ATOM 1182 C CE1 . PHE A 1 158 ? 20.286 -18.067 7.686 1.00 27.14 ? 158 PHE A CE1 1 ATOM 1183 C CE2 . PHE A 1 158 ? 18.333 -18.909 6.564 1.00 26.83 ? 158 PHE A CE2 1 ATOM 1184 C CZ . PHE A 1 158 ? 19.095 -17.838 6.995 1.00 26.66 ? 158 PHE A CZ 1 ATOM 1185 N N . SER A 1 159 ? 21.718 -22.075 10.685 1.00 27.89 ? 159 SER A N 1 ATOM 1186 C CA . SER A 1 159 ? 22.318 -21.587 11.905 1.00 28.19 ? 159 SER A CA 1 ATOM 1187 C C . SER A 1 159 ? 23.746 -21.153 11.671 1.00 27.24 ? 159 SER A C 1 ATOM 1188 O O . SER A 1 159 ? 24.437 -21.712 10.821 1.00 25.20 ? 159 SER A O 1 ATOM 1189 C CB . SER A 1 159 ? 22.280 -22.695 12.958 1.00 29.72 ? 159 SER A CB 1 ATOM 1190 O OG . SER A 1 159 ? 20.943 -23.118 13.165 1.00 32.08 ? 159 SER A OG 1 ATOM 1191 N N . PHE A 1 160 ? 24.187 -20.176 12.458 1.00 27.35 ? 160 PHE A N 1 ATOM 1192 C CA . PHE A 1 160 ? 25.544 -19.644 12.371 1.00 26.38 ? 160 PHE A CA 1 ATOM 1193 C C . PHE A 1 160 ? 26.324 -19.831 13.665 1.00 26.27 ? 160 PHE A C 1 ATOM 1194 O O . PHE A 1 160 ? 25.854 -19.466 14.735 1.00 26.91 ? 160 PHE A O 1 ATOM 1195 C CB . PHE A 1 160 ? 25.501 -18.145 12.035 1.00 25.72 ? 160 PHE A CB 1 ATOM 1196 C CG . PHE A 1 160 ? 25.253 -17.844 10.576 1.00 27.31 ? 160 PHE A CG 1 ATOM 1197 C CD1 . PHE A 1 160 ? 23.973 -17.970 10.027 1.00 27.14 ? 160 PHE A CD1 1 ATOM 1198 C CD2 . PHE A 1 160 ? 26.301 -17.423 9.750 1.00 26.24 ? 160 PHE A CD2 1 ATOM 1199 C CE1 . PHE A 1 160 ? 23.743 -17.684 8.668 1.00 28.64 ? 160 PHE A CE1 1 ATOM 1200 C CE2 . PHE A 1 160 ? 26.084 -17.128 8.395 1.00 25.21 ? 160 PHE A CE2 1 ATOM 1201 C CZ . PHE A 1 160 ? 24.807 -17.249 7.854 1.00 26.28 ? 160 PHE A CZ 1 ATOM 1202 N N . TYR A 1 161 ? 27.518 -20.399 13.552 1.00 26.83 ? 161 TYR A N 1 ATOM 1203 C CA . TYR A 1 161 ? 28.520 -20.306 14.596 1.00 27.04 ? 161 TYR A CA 1 ATOM 1204 C C . TYR A 1 161 ? 29.694 -19.505 14.061 1.00 28.25 ? 161 TYR A C 1 ATOM 1205 O O . TYR A 1 161 ? 30.220 -19.795 12.979 1.00 28.19 ? 161 TYR A O 1 ATOM 1206 C CB . TYR A 1 161 ? 28.984 -21.695 15.050 1.00 28.93 ? 161 TYR A CB 1 ATOM 1207 C CG . TYR A 1 161 ? 30.237 -21.696 15.902 1.00 28.04 ? 161 TYR A CG 1 ATOM 1208 C CD1 . TYR A 1 161 ? 30.246 -21.116 17.160 1.00 29.21 ? 161 TYR A CD1 1 ATOM 1209 C CD2 . TYR A 1 161 ? 31.412 -22.293 15.447 1.00 28.83 ? 161 TYR A CD2 1 ATOM 1210 C CE1 . TYR A 1 161 ? 31.405 -21.115 17.952 1.00 30.06 ? 161 TYR A CE1 1 ATOM 1211 C CE2 . TYR A 1 161 ? 32.573 -22.305 16.226 1.00 27.96 ? 161 TYR A CE2 1 ATOM 1212 C CZ . TYR A 1 161 ? 32.563 -21.716 17.473 1.00 29.40 ? 161 TYR A CZ 1 ATOM 1213 O OH . TYR A 1 161 ? 33.705 -21.723 18.256 1.00 29.95 ? 161 TYR A OH 1 ATOM 1214 N N . TYR A 1 162 ? 30.096 -18.499 14.828 1.00 28.58 ? 162 TYR A N 1 ATOM 1215 C CA . TYR A 1 162 ? 31.290 -17.712 14.541 1.00 29.79 ? 162 TYR A CA 1 ATOM 1216 C C . TYR A 1 162 ? 32.243 -17.791 15.747 1.00 30.81 ? 162 TYR A C 1 ATOM 1217 O O . TYR A 1 162 ? 31.875 -17.372 16.839 1.00 30.76 ? 162 TYR A O 1 ATOM 1218 C CB . TYR A 1 162 ? 30.915 -16.235 14.327 1.00 27.99 ? 162 TYR A CB 1 ATOM 1219 C CG . TYR A 1 162 ? 30.311 -15.830 12.985 1.00 25.90 ? 162 TYR A CG 1 ATOM 1220 C CD1 . TYR A 1 162 ? 30.175 -16.737 11.920 1.00 25.05 ? 162 TYR A CD1 1 ATOM 1221 C CD2 . TYR A 1 162 ? 29.909 -14.520 12.784 1.00 23.46 ? 162 TYR A CD2 1 ATOM 1222 C CE1 . TYR A 1 162 ? 29.638 -16.345 10.706 1.00 23.66 ? 162 TYR A CE1 1 ATOM 1223 C CE2 . TYR A 1 162 ? 29.370 -14.108 11.580 1.00 26.02 ? 162 TYR A CE2 1 ATOM 1224 C CZ . TYR A 1 162 ? 29.232 -15.021 10.540 1.00 27.03 ? 162 TYR A CZ 1 ATOM 1225 O OH . TYR A 1 162 ? 28.703 -14.581 9.344 1.00 27.44 ? 162 TYR A OH 1 ATOM 1226 N N . ASN A 1 163 ? 33.460 -18.295 15.542 1.00 32.28 ? 163 ASN A N 1 ATOM 1227 C CA . ASN A 1 163 ? 34.485 -18.388 16.605 1.00 33.25 ? 163 ASN A CA 1 ATOM 1228 C C . ASN A 1 163 ? 35.194 -17.054 16.821 1.00 35.32 ? 163 ASN A C 1 ATOM 1229 O O . ASN A 1 163 ? 34.980 -16.094 16.082 1.00 34.10 ? 163 ASN A O 1 ATOM 1230 C CB . ASN A 1 163 ? 35.536 -19.448 16.242 1.00 33.18 ? 163 ASN A CB 1 ATOM 1231 C CG . ASN A 1 163 ? 36.110 -20.189 17.471 1.00 35.65 ? 163 ASN A CG 1 ATOM 1232 O OD1 . ASN A 1 163 ? 36.299 -19.619 18.559 1.00 35.27 ? 163 ASN A OD1 1 ATOM 1233 N ND2 . ASN A 1 163 ? 36.398 -21.476 17.284 1.00 34.80 ? 163 ASN A ND2 1 ATOM 1234 N N . ARG A 1 164 ? 36.054 -17.018 17.830 1.00 39.77 ? 164 ARG A N 1 ATOM 1235 C CA . ARG A 1 164 ? 36.955 -15.900 18.075 1.00 46.34 ? 164 ARG A CA 1 ATOM 1236 C C . ARG A 1 164 ? 38.336 -16.228 17.486 1.00 49.13 ? 164 ARG A C 1 ATOM 1237 O O . ARG A 1 164 ? 38.657 -17.396 17.278 1.00 49.57 ? 164 ARG A O 1 ATOM 1238 C CB . ARG A 1 164 ? 37.032 -15.633 19.576 1.00 49.16 ? 164 ARG A CB 1 ATOM 1239 C CG . ARG A 1 164 ? 35.656 -15.433 20.214 1.00 52.21 ? 164 ARG A CG 1 ATOM 1240 C CD . ARG A 1 164 ? 35.689 -15.583 21.730 1.00 54.75 ? 164 ARG A CD 1 ATOM 1241 N NE . ARG A 1 164 ? 34.378 -15.926 22.292 1.00 57.06 ? 164 ARG A NE 1 ATOM 1242 C CZ . ARG A 1 164 ? 33.356 -15.080 22.463 1.00 57.57 ? 164 ARG A CZ 1 ATOM 1243 N NH1 . ARG A 1 164 ? 33.446 -13.795 22.110 1.00 56.84 ? 164 ARG A NH1 1 ATOM 1244 N NH2 . ARG A 1 164 ? 32.222 -15.535 22.988 1.00 57.81 ? 164 ARG A NH2 1 ATOM 1245 N N . ASP A 1 165 ? 39.147 -15.211 17.207 1.00 52.53 ? 165 ASP A N 1 ATOM 1246 C CA . ASP A 1 165 ? 40.412 -15.434 16.492 1.00 56.70 ? 165 ASP A CA 1 ATOM 1247 C C . ASP A 1 165 ? 41.615 -15.510 17.427 1.00 57.90 ? 165 ASP A C 1 ATOM 1248 O O . ASP A 1 165 ? 41.576 -16.226 18.438 1.00 58.55 ? 165 ASP A O 1 ATOM 1249 C CB . ASP A 1 165 ? 40.636 -14.349 15.430 1.00 59.09 ? 165 ASP A CB 1 ATOM 1250 C CG . ASP A 1 165 ? 41.506 -14.827 14.266 1.00 61.37 ? 165 ASP A CG 1 ATOM 1251 O OD1 . ASP A 1 165 ? 41.620 -16.054 14.041 1.00 62.02 ? 165 ASP A OD1 1 ATOM 1252 O OD2 . ASP A 1 165 ? 42.070 -13.965 13.560 1.00 62.58 ? 165 ASP A OD2 1 ATOM 1253 N N . SER B 2 1 ? 42.407 -24.141 13.785 1.00 55.34 ? 171 SER B N 1 ATOM 1254 C CA . SER B 2 1 ? 41.250 -23.563 14.468 1.00 54.07 ? 171 SER B CA 1 ATOM 1255 C C . SER B 2 1 ? 40.003 -23.569 13.569 1.00 51.58 ? 171 SER B C 1 ATOM 1256 O O . SER B 2 1 ? 40.109 -23.310 12.370 1.00 52.47 ? 171 SER B O 1 ATOM 1257 C CB . SER B 2 1 ? 41.574 -22.135 14.908 1.00 54.40 ? 171 SER B CB 1 ATOM 1258 O OG . SER B 2 1 ? 40.838 -21.786 16.066 1.00 56.19 ? 171 SER B OG 1 ATOM 1259 N N . LEU B 2 2 ? 38.837 -23.876 14.142 1.00 47.11 ? 172 LEU B N 1 ATOM 1260 C CA . LEU B 2 2 ? 37.559 -23.753 13.420 1.00 43.67 ? 172 LEU B CA 1 ATOM 1261 C C . LEU B 2 2 ? 37.049 -22.317 13.481 1.00 39.78 ? 172 LEU B C 1 ATOM 1262 O O . LEU B 2 2 ? 36.618 -21.858 14.537 1.00 39.74 ? 172 LEU B O 1 ATOM 1263 C CB . LEU B 2 2 ? 36.487 -24.699 13.989 1.00 43.77 ? 172 LEU B CB 1 ATOM 1264 C CG . LEU B 2 2 ? 35.105 -24.582 13.319 1.00 44.64 ? 172 LEU B CG 1 ATOM 1265 C CD1 . LEU B 2 2 ? 35.140 -25.144 11.911 1.00 44.54 ? 172 LEU B CD1 1 ATOM 1266 C CD2 . LEU B 2 2 ? 33.999 -25.247 14.109 1.00 44.26 ? 172 LEU B CD2 1 ATOM 1267 N N . GLY B 2 3 ? 37.081 -21.625 12.345 1.00 36.50 ? 173 GLY B N 1 ATOM 1268 C CA . GLY B 2 3 ? 36.708 -20.207 12.266 1.00 32.40 ? 173 GLY B CA 1 ATOM 1269 C C . GLY B 2 3 ? 35.233 -19.930 12.467 1.00 31.57 ? 173 GLY B C 1 ATOM 1270 O O . GLY B 2 3 ? 34.841 -18.844 12.918 1.00 31.47 ? 173 GLY B O 1 ATOM 1271 N N . GLY B 2 4 ? 34.416 -20.924 12.144 1.00 30.81 ? 174 GLY B N 1 ATOM 1272 C CA . GLY B 2 4 ? 32.973 -20.800 12.213 1.00 29.26 ? 174 GLY B CA 1 ATOM 1273 C C . GLY B 2 4 ? 32.296 -21.908 11.441 1.00 28.12 ? 174 GLY B C 1 ATOM 1274 O O . GLY B 2 4 ? 32.957 -22.753 10.837 1.00 25.42 ? 174 GLY B O 1 ATOM 1275 N N . GLN B 2 5 ? 30.967 -21.893 11.462 1.00 28.57 ? 175 GLN B N 1 ATOM 1276 C CA . GLN B 2 5 ? 30.173 -22.939 10.855 1.00 28.57 ? 175 GLN B CA 1 ATOM 1277 C C . GLN B 2 5 ? 28.752 -22.460 10.603 1.00 29.82 ? 175 GLN B C 1 ATOM 1278 O O . GLN B 2 5 ? 28.121 -21.827 11.471 1.00 28.09 ? 175 GLN B O 1 ATOM 1279 C CB . GLN B 2 5 ? 30.144 -24.164 11.765 1.00 30.05 ? 175 GLN B CB 1 ATOM 1280 C CG . GLN B 2 5 ? 29.370 -25.345 11.212 1.00 32.18 ? 175 GLN B CG 1 ATOM 1281 C CD . GLN B 2 5 ? 28.978 -26.325 12.299 1.00 34.26 ? 175 GLN B CD 1 ATOM 1282 O OE1 . GLN B 2 5 ? 28.404 -25.941 13.320 1.00 35.89 ? 175 GLN B OE1 1 ATOM 1283 N NE2 . GLN B 2 5 ? 29.279 -27.594 12.087 1.00 34.52 ? 175 GLN B NE2 1 ATOM 1284 N N . ILE B 2 6 ? 28.267 -22.746 9.398 1.00 29.06 ? 176 ILE B N 1 ATOM 1285 C CA . ILE B 2 6 ? 26.861 -22.590 9.079 1.00 30.33 ? 176 ILE B CA 1 ATOM 1286 C C . ILE B 2 6 ? 26.255 -23.970 8.837 1.00 29.28 ? 176 ILE B C 1 ATOM 1287 O O . ILE B 2 6 ? 26.826 -24.799 8.119 1.00 28.19 ? 176 ILE B O 1 ATOM 1288 C CB . ILE B 2 6 ? 26.610 -21.597 7.884 1.00 31.41 ? 176 ILE B CB 1 ATOM 1289 C CG1 . ILE B 2 6 ? 25.254 -21.858 7.216 1.00 32.86 ? 176 ILE B CG1 1 ATOM 1290 C CG2 . ILE B 2 6 ? 27.700 -21.702 6.834 1.00 34.21 ? 176 ILE B CG2 1 ATOM 1291 C CD1 . ILE B 2 6 ? 24.671 -20.630 6.433 1.00 31.68 ? 176 ILE B CD1 1 ATOM 1292 N N . VAL B 2 7 ? 25.117 -24.213 9.477 1.00 29.18 ? 177 VAL B N 1 ATOM 1293 C CA . VAL B 2 7 ? 24.338 -25.424 9.270 1.00 28.76 ? 177 VAL B CA 1 ATOM 1294 C C . VAL B 2 7 ? 23.072 -25.067 8.502 1.00 30.36 ? 177 VAL B C 1 ATOM 1295 O O . VAL B 2 7 ? 22.400 -24.085 8.824 1.00 30.53 ? 177 VAL B O 1 ATOM 1296 C CB . VAL B 2 7 ? 23.964 -26.103 10.606 1.00 28.43 ? 177 VAL B CB 1 ATOM 1297 C CG1 . VAL B 2 7 ? 23.127 -27.360 10.352 1.00 29.07 ? 177 VAL B CG1 1 ATOM 1298 C CG2 . VAL B 2 7 ? 25.206 -26.451 11.392 1.00 27.40 ? 177 VAL B CG2 1 ATOM 1299 N N . LEU B 2 8 ? 22.773 -25.853 7.470 1.00 30.45 ? 178 LEU B N 1 ATOM 1300 C CA . LEU B 2 8 ? 21.534 -25.722 6.719 1.00 29.92 ? 178 LEU B CA 1 ATOM 1301 C C . LEU B 2 8 ? 20.637 -26.864 7.115 1.00 29.30 ? 178 LEU B C 1 ATOM 1302 O O . LEU B 2 8 ? 21.057 -28.013 7.069 1.00 29.42 ? 178 LEU B O 1 ATOM 1303 C CB . LEU B 2 8 ? 21.799 -25.787 5.219 1.00 28.87 ? 178 LEU B CB 1 ATOM 1304 C CG . LEU B 2 8 ? 22.752 -24.726 4.666 1.00 30.26 ? 178 LEU B CG 1 ATOM 1305 C CD1 . LEU B 2 8 ? 23.200 -25.123 3.263 1.00 29.44 ? 178 LEU B CD1 1 ATOM 1306 C CD2 . LEU B 2 8 ? 22.090 -23.335 4.683 1.00 29.60 ? 178 LEU B CD2 1 ATOM 1307 N N . GLY B 2 9 ? 19.410 -26.552 7.516 1.00 29.24 ? 179 GLY B N 1 ATOM 1308 C CA . GLY B 2 9 ? 18.458 -27.585 7.914 1.00 29.78 ? 179 GLY B CA 1 ATOM 1309 C C . GLY B 2 9 ? 18.504 -27.971 9.379 1.00 30.95 ? 179 GLY B C 1 ATOM 1310 O O . GLY B 2 9 ? 17.738 -28.830 9.815 1.00 32.60 ? 179 GLY B O 1 ATOM 1311 N N . GLY B 2 10 ? 19.402 -27.352 10.142 1.00 30.52 ? 180 GLY B N 1 ATOM 1312 C CA . GLY B 2 10 ? 19.459 -27.564 11.581 1.00 29.40 ? 180 GLY B CA 1 ATOM 1313 C C . GLY B 2 10 ? 20.376 -26.623 12.343 1.00 31.41 ? 180 GLY B C 1 ATOM 1314 O O . GLY B 2 10 ? 20.662 -25.483 11.906 1.00 29.03 ? 180 GLY B O 1 ATOM 1315 N N . SER B 2 11 ? 20.826 -27.114 13.498 1.00 31.76 ? 181 SER B N 1 ATOM 1316 C CA . SER B 2 11 ? 21.829 -26.443 14.320 1.00 34.11 ? 181 SER B CA 1 ATOM 1317 C C . SER B 2 11 ? 22.810 -27.496 14.812 1.00 34.92 ? 181 SER B C 1 ATOM 1318 O O . SER B 2 11 ? 22.564 -28.696 14.669 1.00 34.56 ? 181 SER B O 1 ATOM 1319 C CB . SER B 2 11 ? 21.174 -25.710 15.492 1.00 34.06 ? 181 SER B CB 1 ATOM 1320 O OG . SER B 2 11 ? 20.563 -26.631 16.388 1.00 37.46 ? 181 SER B OG 1 ATOM 1321 N N . ASP B 2 12 ? 23.930 -27.052 15.367 1.00 36.49 ? 182 ASP B N 1 ATOM 1322 C CA . ASP B 2 12 ? 24.971 -27.968 15.825 1.00 38.14 ? 182 ASP B CA 1 ATOM 1323 C C . ASP B 2 12 ? 25.194 -27.767 17.325 1.00 39.52 ? 182 ASP B C 1 ATOM 1324 O O . ASP B 2 12 ? 25.848 -26.801 17.732 1.00 40.04 ? 182 ASP B O 1 ATOM 1325 C CB . ASP B 2 12 ? 26.251 -27.745 15.015 1.00 38.13 ? 182 ASP B CB 1 ATOM 1326 C CG . ASP B 2 12 ? 27.336 -28.780 15.299 1.00 39.75 ? 182 ASP B CG 1 ATOM 1327 O OD1 . ASP B 2 12 ? 27.204 -29.587 16.255 1.00 40.21 ? 182 ASP B OD1 1 ATOM 1328 O OD2 . ASP B 2 12 ? 28.343 -28.773 14.548 1.00 39.01 ? 182 ASP B OD2 1 ATOM 1329 N N . PRO B 2 13 ? 24.610 -28.663 18.152 1.00 40.59 ? 183 PRO B N 1 ATOM 1330 C CA . PRO B 2 13 ? 24.660 -28.645 19.625 1.00 42.18 ? 183 PRO B CA 1 ATOM 1331 C C . PRO B 2 13 ? 26.061 -28.605 20.232 1.00 43.05 ? 183 PRO B C 1 ATOM 1332 O O . PRO B 2 13 ? 26.220 -28.183 21.378 1.00 43.66 ? 183 PRO B O 1 ATOM 1333 C CB . PRO B 2 13 ? 23.961 -29.954 20.011 1.00 41.34 ? 183 PRO B CB 1 ATOM 1334 C CG . PRO B 2 13 ? 23.016 -30.191 18.898 1.00 41.58 ? 183 PRO B CG 1 ATOM 1335 C CD . PRO B 2 13 ? 23.786 -29.784 17.667 1.00 40.94 ? 183 PRO B CD 1 ATOM 1336 N N . GLN B 2 14 ? 27.072 -29.031 19.479 1.00 44.10 ? 184 GLN B N 1 ATOM 1337 C CA . GLN B 2 14 ? 28.432 -29.007 20.003 1.00 45.11 ? 184 GLN B CA 1 ATOM 1338 C C . GLN B 2 14 ? 28.997 -27.575 20.045 1.00 42.22 ? 184 GLN B C 1 ATOM 1339 O O . GLN B 2 14 ? 30.065 -27.351 20.598 1.00 42.21 ? 184 GLN B O 1 ATOM 1340 C CB . GLN B 2 14 ? 29.348 -30.032 19.272 1.00 46.82 ? 184 GLN B CB 1 ATOM 1341 C CG . GLN B 2 14 ? 29.868 -29.640 17.877 1.00 48.47 ? 184 GLN B CG 1 ATOM 1342 C CD . GLN B 2 14 ? 30.221 -30.849 16.959 1.00 49.59 ? 184 GLN B CD 1 ATOM 1343 O OE1 . GLN B 2 14 ? 30.133 -30.753 15.718 1.00 48.66 ? 184 GLN B OE1 1 ATOM 1344 N NE2 . GLN B 2 14 ? 30.622 -31.975 17.566 1.00 49.61 ? 184 GLN B NE2 1 ATOM 1345 N N . HIS B 2 15 ? 28.250 -26.609 19.501 1.00 40.96 ? 185 HIS B N 1 ATOM 1346 C CA . HIS B 2 15 ? 28.710 -25.216 19.402 1.00 38.29 ? 185 HIS B CA 1 ATOM 1347 C C . HIS B 2 15 ? 27.888 -24.162 20.157 1.00 37.51 ? 185 HIS B C 1 ATOM 1348 O O . HIS B 2 15 ? 28.237 -22.974 20.160 1.00 34.56 ? 185 HIS B O 1 ATOM 1349 C CB . HIS B 2 15 ? 28.884 -24.821 17.939 1.00 38.44 ? 185 HIS B CB 1 ATOM 1350 C CG . HIS B 2 15 ? 30.066 -25.465 17.293 1.00 39.70 ? 185 HIS B CG 1 ATOM 1351 N ND1 . HIS B 2 15 ? 29.982 -26.154 16.104 1.00 41.91 ? 185 HIS B ND1 1 ATOM 1352 C CD2 . HIS B 2 15 ? 31.356 -25.555 17.692 1.00 39.96 ? 185 HIS B CD2 1 ATOM 1353 C CE1 . HIS B 2 15 ? 31.175 -26.623 15.786 1.00 41.79 ? 185 HIS B CE1 1 ATOM 1354 N NE2 . HIS B 2 15 ? 32.025 -26.278 16.737 1.00 41.25 ? 185 HIS B NE2 1 ATOM 1355 N N . TYR B 2 16 ? 26.798 -24.595 20.779 1.00 37.41 ? 186 TYR B N 1 ATOM 1356 C CA . TYR B 2 16 ? 26.045 -23.737 21.693 1.00 38.24 ? 186 TYR B CA 1 ATOM 1357 C C . TYR B 2 16 ? 25.695 -24.488 22.975 1.00 39.24 ? 186 TYR B C 1 ATOM 1358 O O . TYR B 2 16 ? 25.781 -25.716 23.031 1.00 37.93 ? 186 TYR B O 1 ATOM 1359 C CB . TYR B 2 16 ? 24.788 -23.167 21.031 1.00 37.61 ? 186 TYR B CB 1 ATOM 1360 C CG . TYR B 2 16 ? 23.763 -24.194 20.603 1.00 37.18 ? 186 TYR B CG 1 ATOM 1361 C CD1 . TYR B 2 16 ? 23.763 -24.695 19.303 1.00 36.08 ? 186 TYR B CD1 1 ATOM 1362 C CD2 . TYR B 2 16 ? 22.779 -24.646 21.490 1.00 36.54 ? 186 TYR B CD2 1 ATOM 1363 C CE1 . TYR B 2 16 ? 22.835 -25.634 18.895 1.00 36.21 ? 186 TYR B CE1 1 ATOM 1364 C CE2 . TYR B 2 16 ? 21.836 -25.585 21.092 1.00 37.46 ? 186 TYR B CE2 1 ATOM 1365 C CZ . TYR B 2 16 ? 21.873 -26.079 19.788 1.00 38.24 ? 186 TYR B CZ 1 ATOM 1366 O OH . TYR B 2 16 ? 20.950 -27.016 19.371 1.00 38.47 ? 186 TYR B OH 1 ATOM 1367 N N . GLU B 2 17 ? 25.313 -23.756 24.010 1.00 41.33 ? 187 GLU B N 1 ATOM 1368 C CA . GLU B 2 17 ? 24.881 -24.410 25.232 1.00 44.67 ? 187 GLU B CA 1 ATOM 1369 C C . GLU B 2 17 ? 23.504 -23.964 25.711 1.00 44.66 ? 187 GLU B C 1 ATOM 1370 O O . GLU B 2 17 ? 23.078 -22.837 25.465 1.00 45.87 ? 187 GLU B O 1 ATOM 1371 C CB . GLU B 2 17 ? 25.941 -24.312 26.328 1.00 46.71 ? 187 GLU B CB 1 ATOM 1372 C CG . GLU B 2 17 ? 26.160 -22.953 26.912 1.00 50.95 ? 187 GLU B CG 1 ATOM 1373 C CD . GLU B 2 17 ? 27.135 -23.004 28.077 1.00 53.95 ? 187 GLU B CD 1 ATOM 1374 O OE1 . GLU B 2 17 ? 28.339 -23.250 27.828 1.00 55.48 ? 187 GLU B OE1 1 ATOM 1375 O OE2 . GLU B 2 17 ? 26.693 -22.809 29.236 1.00 55.14 ? 187 GLU B OE2 1 ATOM 1376 N N . GLY B 2 18 ? 22.810 -24.870 26.384 1.00 44.25 ? 188 GLY B N 1 ATOM 1377 C CA . GLY B 2 18 ? 21.459 -24.610 26.838 1.00 44.79 ? 188 GLY B CA 1 ATOM 1378 C C . GLY B 2 18 ? 20.464 -24.754 25.708 1.00 45.82 ? 188 GLY B C 1 ATOM 1379 O O . GLY B 2 18 ? 20.627 -25.576 24.805 1.00 45.80 ? 188 GLY B O 1 ATOM 1380 N N . ASN B 2 19 ? 19.426 -23.939 25.762 1.00 46.84 ? 189 ASN B N 1 ATOM 1381 C CA . ASN B 2 19 ? 18.374 -23.983 24.767 1.00 47.37 ? 189 ASN B CA 1 ATOM 1382 C C . ASN B 2 19 ? 18.201 -22.628 24.112 1.00 45.26 ? 189 ASN B C 1 ATOM 1383 O O . ASN B 2 19 ? 18.563 -21.597 24.686 1.00 45.34 ? 189 ASN B O 1 ATOM 1384 C CB . ASN B 2 19 ? 17.060 -24.450 25.406 1.00 49.17 ? 189 ASN B CB 1 ATOM 1385 C CG . ASN B 2 19 ? 17.005 -25.953 25.578 1.00 50.49 ? 189 ASN B CG 1 ATOM 1386 O OD1 . ASN B 2 19 ? 16.838 -26.703 24.605 1.00 50.89 ? 189 ASN B OD1 1 ATOM 1387 N ND2 . ASN B 2 19 ? 17.144 -26.408 26.818 1.00 50.27 ? 189 ASN B ND2 1 ATOM 1388 N N . PHE B 2 20 ? 17.660 -22.642 22.901 1.00 42.51 ? 190 PHE B N 1 ATOM 1389 C CA . PHE B 2 20 ? 17.407 -21.422 22.161 1.00 40.52 ? 190 PHE B CA 1 ATOM 1390 C C . PHE B 2 20 ? 16.341 -20.582 22.843 1.00 40.38 ? 190 PHE B C 1 ATOM 1391 O O . PHE B 2 20 ? 15.442 -21.120 23.478 1.00 41.77 ? 190 PHE B O 1 ATOM 1392 C CB . PHE B 2 20 ? 16.962 -21.754 20.738 1.00 39.58 ? 190 PHE B CB 1 ATOM 1393 C CG . PHE B 2 20 ? 18.090 -22.142 19.820 1.00 40.75 ? 190 PHE B CG 1 ATOM 1394 C CD1 . PHE B 2 20 ? 19.125 -21.250 19.546 1.00 40.14 ? 190 PHE B CD1 1 ATOM 1395 C CD2 . PHE B 2 20 ? 18.113 -23.392 19.217 1.00 41.32 ? 190 PHE B CD2 1 ATOM 1396 C CE1 . PHE B 2 20 ? 20.166 -21.603 18.703 1.00 39.73 ? 190 PHE B CE1 1 ATOM 1397 C CE2 . PHE B 2 20 ? 19.154 -23.748 18.362 1.00 41.87 ? 190 PHE B CE2 1 ATOM 1398 C CZ . PHE B 2 20 ? 20.179 -22.847 18.107 1.00 39.92 ? 190 PHE B CZ 1 ATOM 1399 N N . HIS B 2 21 ? 16.457 -19.265 22.714 1.00 38.94 ? 191 HIS B N 1 ATOM 1400 C CA . HIS B 2 21 ? 15.351 -18.368 23.003 1.00 38.08 ? 191 HIS B CA 1 ATOM 1401 C C . HIS B 2 21 ? 14.998 -17.679 21.717 1.00 37.15 ? 191 HIS B C 1 ATOM 1402 O O . HIS B 2 21 ? 15.887 -17.279 20.966 1.00 35.72 ? 191 HIS B O 1 ATOM 1403 C CB . HIS B 2 21 ? 15.722 -17.362 24.086 1.00 40.11 ? 191 HIS B CB 1 ATOM 1404 C CG . HIS B 2 21 ? 16.053 -18.008 25.390 1.00 42.42 ? 191 HIS B CG 1 ATOM 1405 N ND1 . HIS B 2 21 ? 17.346 -18.302 25.765 1.00 43.99 ? 191 HIS B ND1 1 ATOM 1406 C CD2 . HIS B 2 21 ? 15.256 -18.462 26.386 1.00 43.63 ? 191 HIS B CD2 1 ATOM 1407 C CE1 . HIS B 2 21 ? 17.334 -18.887 26.950 1.00 44.96 ? 191 HIS B CE1 1 ATOM 1408 N NE2 . HIS B 2 21 ? 16.077 -18.997 27.347 1.00 45.39 ? 191 HIS B NE2 1 ATOM 1409 N N . TYR B 2 22 ? 13.700 -17.563 21.448 1.00 35.67 ? 192 TYR B N 1 ATOM 1410 C CA . TYR B 2 22 ? 13.264 -17.082 20.150 1.00 35.17 ? 192 TYR B CA 1 ATOM 1411 C C . TYR B 2 22 ? 12.549 -15.755 20.225 1.00 35.54 ? 192 TYR B C 1 ATOM 1412 O O . TYR B 2 22 ? 11.847 -15.447 21.206 1.00 33.34 ? 192 TYR B O 1 ATOM 1413 C CB . TYR B 2 22 ? 12.364 -18.094 19.440 1.00 34.98 ? 192 TYR B CB 1 ATOM 1414 C CG . TYR B 2 22 ? 12.982 -19.443 19.177 1.00 34.96 ? 192 TYR B CG 1 ATOM 1415 C CD1 . TYR B 2 22 ? 13.702 -19.693 18.007 1.00 34.96 ? 192 TYR B CD1 1 ATOM 1416 C CD2 . TYR B 2 22 ? 12.810 -20.483 20.083 1.00 33.62 ? 192 TYR B CD2 1 ATOM 1417 C CE1 . TYR B 2 22 ? 14.259 -20.950 17.759 1.00 34.44 ? 192 TYR B CE1 1 ATOM 1418 C CE2 . TYR B 2 22 ? 13.349 -21.735 19.845 1.00 34.67 ? 192 TYR B CE2 1 ATOM 1419 C CZ . TYR B 2 22 ? 14.076 -21.967 18.690 1.00 34.85 ? 192 TYR B CZ 1 ATOM 1420 O OH . TYR B 2 22 ? 14.604 -23.227 18.482 1.00 34.56 ? 192 TYR B OH 1 ATOM 1421 N N . ILE B 2 23 ? 12.742 -14.985 19.159 1.00 34.46 ? 193 ILE B N 1 ATOM 1422 C CA . ILE B 2 23 ? 12.058 -13.723 18.955 1.00 35.54 ? 193 ILE B CA 1 ATOM 1423 C C . ILE B 2 23 ? 11.442 -13.784 17.558 1.00 36.71 ? 193 ILE B C 1 ATOM 1424 O O . ILE B 2 23 ? 12.107 -14.202 16.599 1.00 37.32 ? 193 ILE B O 1 ATOM 1425 C CB . ILE B 2 23 ? 13.025 -12.516 19.071 1.00 33.45 ? 193 ILE B CB 1 ATOM 1426 C CG1 . ILE B 2 23 ? 13.826 -12.579 20.372 1.00 33.33 ? 193 ILE B CG1 1 ATOM 1427 C CG2 . ILE B 2 23 ? 12.269 -11.213 19.019 1.00 34.04 ? 193 ILE B CG2 1 ATOM 1428 C CD1 . ILE B 2 23 ? 15.217 -13.215 20.239 1.00 32.88 ? 193 ILE B CD1 1 ATOM 1429 N N . ASN B 2 24 ? 10.173 -13.395 17.468 1.00 35.84 ? 194 ASN B N 1 ATOM 1430 C CA . ASN B 2 24 ? 9.451 -13.300 16.208 1.00 37.48 ? 194 ASN B CA 1 ATOM 1431 C C . ASN B 2 24 ? 9.930 -12.108 15.390 1.00 37.98 ? 194 ASN B C 1 ATOM 1432 O O . ASN B 2 24 ? 10.233 -11.048 15.937 1.00 37.48 ? 194 ASN B O 1 ATOM 1433 C CB . ASN B 2 24 ? 7.939 -13.137 16.465 1.00 37.92 ? 194 ASN B CB 1 ATOM 1434 C CG . ASN B 2 24 ? 7.216 -14.465 16.652 1.00 38.49 ? 194 ASN B CG 1 ATOM 1435 O OD1 . ASN B 2 24 ? 5.981 -14.510 16.711 1.00 39.20 ? 194 ASN B OD1 1 ATOM 1436 N ND2 . ASN B 2 24 ? 7.974 -15.549 16.748 1.00 38.10 ? 194 ASN B ND2 1 ATOM 1437 N N . LEU B 2 25 ? 9.972 -12.276 14.076 1.00 38.68 ? 195 LEU B N 1 ATOM 1438 C CA . LEU B 2 25 ? 10.296 -11.164 13.197 1.00 40.28 ? 195 LEU B CA 1 ATOM 1439 C C . LEU B 2 25 ? 9.166 -10.137 13.268 1.00 41.51 ? 195 LEU B C 1 ATOM 1440 O O . LEU B 2 25 ? 8.016 -10.488 13.556 1.00 41.49 ? 195 LEU B O 1 ATOM 1441 C CB . LEU B 2 25 ? 10.512 -11.645 11.759 1.00 39.40 ? 195 LEU B CB 1 ATOM 1442 C CG . LEU B 2 25 ? 11.517 -12.772 11.468 1.00 38.66 ? 195 LEU B CG 1 ATOM 1443 C CD1 . LEU B 2 25 ? 11.624 -12.981 9.963 1.00 38.02 ? 195 LEU B CD1 1 ATOM 1444 C CD2 . LEU B 2 25 ? 12.894 -12.505 12.075 1.00 36.58 ? 195 LEU B CD2 1 ATOM 1445 N N . ILE B 2 26 ? 9.510 -8.875 13.035 1.00 42.38 ? 196 ILE B N 1 ATOM 1446 C CA . ILE B 2 26 ? 8.541 -7.789 13.033 1.00 46.23 ? 196 ILE B CA 1 ATOM 1447 C C . ILE B 2 26 ? 7.575 -7.980 11.873 1.00 48.32 ? 196 ILE B C 1 ATOM 1448 O O . ILE B 2 26 ? 6.358 -8.052 12.072 1.00 48.86 ? 196 ILE B O 1 ATOM 1449 C CB . ILE B 2 26 ? 9.243 -6.418 12.956 1.00 46.78 ? 196 ILE B CB 1 ATOM 1450 C CG1 . ILE B 2 26 ? 9.879 -6.104 14.307 1.00 46.99 ? 196 ILE B CG1 1 ATOM 1451 C CG2 . ILE B 2 26 ? 8.259 -5.307 12.537 1.00 47.25 ? 196 ILE B CG2 1 ATOM 1452 C CD1 . ILE B 2 26 ? 11.057 -5.189 14.220 1.00 47.46 ? 196 ILE B CD1 1 ATOM 1453 N N . LYS B 2 27 ? 8.142 -8.064 10.672 1.00 49.46 ? 197 LYS B N 1 ATOM 1454 C CA . LYS B 2 27 ? 7.426 -8.450 9.467 1.00 49.96 ? 197 LYS B CA 1 ATOM 1455 C C . LYS B 2 27 ? 8.312 -9.419 8.702 1.00 50.03 ? 197 LYS B C 1 ATOM 1456 O O . LYS B 2 27 ? 9.541 -9.252 8.670 1.00 50.27 ? 197 LYS B O 1 ATOM 1457 C CB . LYS B 2 27 ? 7.112 -7.228 8.596 1.00 51.20 ? 197 LYS B CB 1 ATOM 1458 C CG . LYS B 2 27 ? 8.275 -6.243 8.421 1.00 53.78 ? 197 LYS B CG 1 ATOM 1459 C CD . LYS B 2 27 ? 8.272 -5.605 7.037 1.00 55.55 ? 197 LYS B CD 1 ATOM 1460 C CE . LYS B 2 27 ? 8.822 -4.182 7.076 1.00 57.39 ? 197 LYS B CE 1 ATOM 1461 N NZ . LYS B 2 27 ? 10.263 -4.108 7.476 1.00 58.27 ? 197 LYS B NZ 1 ATOM 1462 N N . THR B 2 28 ? 7.702 -10.443 8.105 1.00 48.45 ? 198 THR B N 1 ATOM 1463 C CA . THR B 2 28 ? 8.430 -11.333 7.208 1.00 46.18 ? 198 THR B CA 1 ATOM 1464 C C . THR B 2 28 ? 8.993 -10.476 6.074 1.00 44.03 ? 198 THR B C 1 ATOM 1465 O O . THR B 2 28 ? 8.509 -9.370 5.824 1.00 44.29 ? 198 THR B O 1 ATOM 1466 C CB . THR B 2 28 ? 7.552 -12.515 6.684 1.00 47.94 ? 198 THR B CB 1 ATOM 1467 O OG1 . THR B 2 28 ? 8.387 -13.500 6.052 1.00 48.87 ? 198 THR B OG1 1 ATOM 1468 C CG2 . THR B 2 28 ? 6.467 -12.040 5.703 1.00 46.64 ? 198 THR B CG2 1 ATOM 1469 N N . GLY B 2 29 ? 10.041 -10.956 5.421 1.00 41.26 ? 199 GLY B N 1 ATOM 1470 C CA . GLY B 2 29 ? 10.682 -10.161 4.388 1.00 38.38 ? 199 GLY B CA 1 ATOM 1471 C C . GLY B 2 29 ? 12.039 -9.616 4.784 1.00 36.13 ? 199 GLY B C 1 ATOM 1472 O O . GLY B 2 29 ? 12.808 -9.204 3.925 1.00 35.73 ? 199 GLY B O 1 ATOM 1473 N N . VAL B 2 30 ? 12.331 -9.621 6.081 1.00 35.61 ? 200 VAL B N 1 ATOM 1474 C CA . VAL B 2 30 ? 13.622 -9.174 6.599 1.00 36.01 ? 200 VAL B CA 1 ATOM 1475 C C . VAL B 2 30 ? 13.968 -9.859 7.929 1.00 35.30 ? 200 VAL B C 1 ATOM 1476 O O . VAL B 2 30 ? 13.077 -10.154 8.736 1.00 36.54 ? 200 VAL B O 1 ATOM 1477 C CB . VAL B 2 30 ? 13.674 -7.637 6.734 1.00 37.56 ? 200 VAL B CB 1 ATOM 1478 C CG1 . VAL B 2 30 ? 12.585 -7.129 7.663 1.00 38.84 ? 200 VAL B CG1 1 ATOM 1479 C CG2 . VAL B 2 30 ? 15.059 -7.174 7.190 1.00 37.05 ? 200 VAL B CG2 1 ATOM 1480 N N . TRP B 2 31 ? 15.257 -10.124 8.146 1.00 31.58 ? 201 TRP B N 1 ATOM 1481 C CA . TRP B 2 31 ? 15.698 -10.762 9.376 1.00 29.86 ? 201 TRP B CA 1 ATOM 1482 C C . TRP B 2 31 ? 15.907 -9.717 10.474 1.00 29.98 ? 201 TRP B C 1 ATOM 1483 O O . TRP B 2 31 ? 17.014 -9.550 10.988 1.00 29.56 ? 201 TRP B O 1 ATOM 1484 C CB . TRP B 2 31 ? 16.963 -11.583 9.152 1.00 27.05 ? 201 TRP B CB 1 ATOM 1485 C CG . TRP B 2 31 ? 16.768 -12.804 8.337 1.00 26.56 ? 201 TRP B CG 1 ATOM 1486 C CD1 . TRP B 2 31 ? 17.266 -13.041 7.091 1.00 25.62 ? 201 TRP B CD1 1 ATOM 1487 C CD2 . TRP B 2 31 ? 16.035 -13.986 8.709 1.00 27.69 ? 201 TRP B CD2 1 ATOM 1488 N NE1 . TRP B 2 31 ? 16.889 -14.286 6.661 1.00 25.42 ? 201 TRP B NE1 1 ATOM 1489 C CE2 . TRP B 2 31 ? 16.130 -14.888 7.629 1.00 26.22 ? 201 TRP B CE2 1 ATOM 1490 C CE3 . TRP B 2 31 ? 15.298 -14.363 9.844 1.00 27.14 ? 201 TRP B CE3 1 ATOM 1491 C CZ2 . TRP B 2 31 ? 15.528 -16.149 7.652 1.00 26.68 ? 201 TRP B CZ2 1 ATOM 1492 C CZ3 . TRP B 2 31 ? 14.692 -15.614 9.865 1.00 26.06 ? 201 TRP B CZ3 1 ATOM 1493 C CH2 . TRP B 2 31 ? 14.809 -16.491 8.774 1.00 27.01 ? 201 TRP B CH2 1 ATOM 1494 N N . GLN B 2 32 ? 14.814 -9.047 10.838 1.00 29.81 ? 202 GLN B N 1 ATOM 1495 C CA . GLN B 2 32 ? 14.816 -7.964 11.807 1.00 30.87 ? 202 GLN B CA 1 ATOM 1496 C C . GLN B 2 32 ? 13.812 -8.257 12.924 1.00 33.52 ? 202 GLN B C 1 ATOM 1497 O O . GLN B 2 32 ? 12.707 -8.738 12.661 1.00 34.87 ? 202 GLN B O 1 ATOM 1498 C CB . GLN B 2 32 ? 14.469 -6.660 11.095 1.00 30.28 ? 202 GLN B CB 1 ATOM 1499 C CG . GLN B 2 32 ? 14.667 -5.382 11.878 1.00 28.61 ? 202 GLN B CG 1 ATOM 1500 C CD . GLN B 2 32 ? 14.464 -4.161 10.991 1.00 29.45 ? 202 GLN B CD 1 ATOM 1501 O OE1 . GLN B 2 32 ? 15.285 -3.238 10.970 1.00 29.31 ? 202 GLN B OE1 1 ATOM 1502 N NE2 . GLN B 2 32 ? 13.385 -4.170 10.226 1.00 28.55 ? 202 GLN B NE2 1 ATOM 1503 N N . ILE B 2 33 ? 14.214 -7.981 14.166 1.00 33.70 ? 203 ILE B N 1 ATOM 1504 C CA . ILE B 2 33 ? 13.365 -8.192 15.343 1.00 34.74 ? 203 ILE B CA 1 ATOM 1505 C C . ILE B 2 33 ? 13.253 -6.913 16.191 1.00 37.38 ? 203 ILE B C 1 ATOM 1506 O O . ILE B 2 33 ? 14.038 -5.973 16.024 1.00 39.36 ? 203 ILE B O 1 ATOM 1507 C CB . ILE B 2 33 ? 13.849 -9.401 16.203 1.00 33.51 ? 203 ILE B CB 1 ATOM 1508 C CG1 . ILE B 2 33 ? 15.336 -9.266 16.566 1.00 33.32 ? 203 ILE B CG1 1 ATOM 1509 C CG2 . ILE B 2 33 ? 13.620 -10.708 15.452 1.00 33.05 ? 203 ILE B CG2 1 ATOM 1510 C CD1 . ILE B 2 33 ? 15.848 -10.260 17.597 1.00 32.59 ? 203 ILE B CD1 1 ATOM 1511 N N . GLN B 2 34 ? 12.258 -6.865 17.073 1.00 39.48 ? 204 GLN B N 1 ATOM 1512 C CA . GLN B 2 34 ? 12.124 -5.760 18.032 1.00 40.52 ? 204 GLN B CA 1 ATOM 1513 C C . GLN B 2 34 ? 13.194 -5.825 19.124 1.00 39.09 ? 204 GLN B C 1 ATOM 1514 O O . GLN B 2 34 ? 13.462 -6.895 19.676 1.00 38.04 ? 204 GLN B O 1 ATOM 1515 C CB . GLN B 2 34 ? 10.734 -5.771 18.676 1.00 42.17 ? 204 GLN B CB 1 ATOM 1516 C CG . GLN B 2 34 ? 10.502 -4.663 19.716 1.00 46.98 ? 204 GLN B CG 1 ATOM 1517 C CD . GLN B 2 34 ? 9.659 -3.517 19.183 1.00 50.87 ? 204 GLN B CD 1 ATOM 1518 O OE1 . GLN B 2 34 ? 8.497 -3.716 18.794 1.00 53.19 ? 204 GLN B OE1 1 ATOM 1519 N NE2 . GLN B 2 34 ? 10.230 -2.304 19.169 1.00 51.53 ? 204 GLN B NE2 1 ATOM 1520 N N . MET B 2 35 ? 13.788 -4.675 19.437 1.00 37.86 ? 205 MET B N 1 ATOM 1521 C CA . MET B 2 35 ? 14.681 -4.552 20.585 1.00 38.47 ? 205 MET B CA 1 ATOM 1522 C C . MET B 2 35 ? 14.072 -3.617 21.640 1.00 40.44 ? 205 MET B C 1 ATOM 1523 O O . MET B 2 35 ? 13.488 -2.568 21.312 1.00 40.44 ? 205 MET B O 1 ATOM 1524 C CB . MET B 2 35 ? 16.071 -4.075 20.142 1.00 38.31 ? 205 MET B CB 1 ATOM 1525 C CG . MET B 2 35 ? 17.139 -4.136 21.237 1.00 38.30 ? 205 MET B CG 1 ATOM 1526 S SD . MET B 2 35 ? 18.836 -4.178 20.620 1.00 39.34 ? 205 MET B SD 1 ATOM 1527 C CE . MET B 2 35 ? 18.885 -2.698 19.625 1.00 36.86 ? 205 MET B CE 1 ATOM 1528 N N . LYS B 2 36 ? 14.207 -4.005 22.903 1.00 41.19 ? 206 LYS B N 1 ATOM 1529 C CA . LYS B 2 36 ? 13.575 -3.280 24.004 1.00 43.45 ? 206 LYS B CA 1 ATOM 1530 C C . LYS B 2 36 ? 14.555 -2.561 24.931 1.00 44.62 ? 206 LYS B C 1 ATOM 1531 O O . LYS B 2 36 ? 14.193 -2.196 26.050 1.00 47.18 ? 206 LYS B O 1 ATOM 1532 C CB . LYS B 2 36 ? 12.700 -4.224 24.827 1.00 43.88 ? 206 LYS B CB 1 ATOM 1533 C CG . LYS B 2 36 ? 11.745 -5.032 23.997 1.00 45.06 ? 206 LYS B CG 1 ATOM 1534 C CD . LYS B 2 36 ? 11.024 -6.035 24.844 1.00 46.54 ? 206 LYS B CD 1 ATOM 1535 C CE . LYS B 2 36 ? 10.354 -7.062 23.967 1.00 47.83 ? 206 LYS B CE 1 ATOM 1536 N NZ . LYS B 2 36 ? 9.774 -8.168 24.777 1.00 49.71 ? 206 LYS B NZ 1 ATOM 1537 N N . GLY B 2 37 ? 15.784 -2.347 24.473 1.00 44.19 ? 207 GLY B N 1 ATOM 1538 C CA . GLY B 2 37 ? 16.747 -1.594 25.264 1.00 43.42 ? 207 GLY B CA 1 ATOM 1539 C C . GLY B 2 37 ? 18.194 -1.985 25.087 1.00 42.25 ? 207 GLY B C 1 ATOM 1540 O O . GLY B 2 37 ? 18.512 -3.099 24.668 1.00 42.50 ? 207 GLY B O 1 ATOM 1541 N N . VAL B 2 38 ? 19.069 -1.035 25.392 1.00 41.85 ? 208 VAL B N 1 ATOM 1542 C CA . VAL B 2 38 ? 20.505 -1.253 25.388 1.00 41.50 ? 208 VAL B CA 1 ATOM 1543 C C . VAL B 2 38 ? 21.031 -0.645 26.676 1.00 41.92 ? 208 VAL B C 1 ATOM 1544 O O . VAL B 2 38 ? 20.892 0.559 26.914 1.00 39.85 ? 208 VAL B O 1 ATOM 1545 C CB . VAL B 2 38 ? 21.221 -0.601 24.162 1.00 41.79 ? 208 VAL B CB 1 ATOM 1546 C CG1 . VAL B 2 38 ? 22.697 -1.000 24.124 1.00 41.59 ? 208 VAL B CG1 1 ATOM 1547 C CG2 . VAL B 2 38 ? 20.544 -0.975 22.851 1.00 42.04 ? 208 VAL B CG2 1 ATOM 1548 N N . SER B 2 39 ? 21.619 -1.492 27.510 1.00 43.42 ? 209 SER B N 1 ATOM 1549 C CA . SER B 2 39 ? 22.152 -1.062 28.786 1.00 45.29 ? 209 SER B CA 1 ATOM 1550 C C . SER B 2 39 ? 23.650 -0.925 28.688 1.00 45.92 ? 209 SER B C 1 ATOM 1551 O O . SER B 2 39 ? 24.325 -1.821 28.192 1.00 46.45 ? 209 SER B O 1 ATOM 1552 C CB . SER B 2 39 ? 21.821 -2.081 29.879 1.00 45.97 ? 209 SER B CB 1 ATOM 1553 O OG . SER B 2 39 ? 20.428 -2.176 30.094 1.00 48.66 ? 209 SER B OG 1 ATOM 1554 N N . VAL B 2 40 ? 24.163 0.209 29.142 1.00 47.31 ? 210 VAL B N 1 ATOM 1555 C CA . VAL B 2 40 ? 25.570 0.317 29.483 1.00 49.28 ? 210 VAL B CA 1 ATOM 1556 C C . VAL B 2 40 ? 25.639 0.088 30.987 1.00 51.32 ? 210 VAL B C 1 ATOM 1557 O O . VAL B 2 40 ? 24.946 0.760 31.758 1.00 52.69 ? 210 VAL B O 1 ATOM 1558 C CB . VAL B 2 40 ? 26.157 1.672 29.098 1.00 48.70 ? 210 VAL B CB 1 ATOM 1559 C CG1 . VAL B 2 40 ? 27.551 1.819 29.680 1.00 50.51 ? 210 VAL B CG1 1 ATOM 1560 C CG2 . VAL B 2 40 ? 26.210 1.804 27.594 1.00 47.41 ? 210 VAL B CG2 1 ATOM 1561 N N . GLY B 2 41 ? 26.449 -0.879 31.403 1.00 52.61 ? 211 GLY B N 1 ATOM 1562 C CA . GLY B 2 41 ? 26.387 -1.366 32.772 1.00 54.58 ? 211 GLY B CA 1 ATOM 1563 C C . GLY B 2 41 ? 24.971 -1.824 33.074 1.00 56.73 ? 211 GLY B C 1 ATOM 1564 O O . GLY B 2 41 ? 24.421 -2.657 32.357 1.00 57.12 ? 211 GLY B O 1 ATOM 1565 N N . SER B 2 42 ? 24.368 -1.255 34.115 1.00 59.07 ? 212 SER B N 1 ATOM 1566 C CA . SER B 2 42 ? 23.043 -1.694 34.570 1.00 60.70 ? 212 SER B CA 1 ATOM 1567 C C . SER B 2 42 ? 21.914 -0.682 34.301 1.00 60.99 ? 212 SER B C 1 ATOM 1568 O O . SER B 2 42 ? 20.778 -0.878 34.745 1.00 61.02 ? 212 SER B O 1 ATOM 1569 C CB . SER B 2 42 ? 23.087 -2.072 36.059 1.00 61.60 ? 212 SER B CB 1 ATOM 1570 O OG . SER B 2 42 ? 23.056 -0.922 36.889 1.00 61.67 ? 212 SER B OG 1 ATOM 1571 N N . SER B 2 43 ? 22.229 0.387 33.570 1.00 60.81 ? 213 SER B N 1 ATOM 1572 C CA . SER B 2 43 ? 21.252 1.435 33.280 1.00 60.57 ? 213 SER B CA 1 ATOM 1573 C C . SER B 2 43 ? 20.922 1.511 31.790 1.00 59.90 ? 213 SER B C 1 ATOM 1574 O O . SER B 2 43 ? 21.828 1.546 30.942 1.00 59.26 ? 213 SER B O 1 ATOM 1575 C CB . SER B 2 43 ? 21.736 2.800 33.799 1.00 61.06 ? 213 SER B CB 1 ATOM 1576 O OG . SER B 2 43 ? 22.826 3.303 33.040 1.00 61.39 ? 213 SER B OG 1 ATOM 1577 N N . THR B 2 44 ? 19.624 1.552 31.485 1.00 58.23 ? 214 THR B N 1 ATOM 1578 C CA . THR B 2 44 ? 19.154 1.558 30.102 1.00 57.42 ? 214 THR B CA 1 ATOM 1579 C C . THR B 2 44 ? 19.335 2.927 29.448 1.00 56.80 ? 214 THR B C 1 ATOM 1580 O O . THR B 2 44 ? 18.441 3.779 29.483 1.00 58.68 ? 214 THR B O 1 ATOM 1581 C CB . THR B 2 44 ? 17.691 1.073 29.987 1.00 57.61 ? 214 THR B CB 1 ATOM 1582 O OG1 . THR B 2 44 ? 17.491 -0.055 30.849 1.00 57.70 ? 214 THR B OG1 1 ATOM 1583 C CG2 . THR B 2 44 ? 17.370 0.666 28.544 1.00 57.57 ? 214 THR B CG2 1 ATOM 1584 N N . LEU B 2 45 ? 20.505 3.125 28.854 1.00 54.40 ? 215 LEU B N 1 ATOM 1585 C CA . LEU B 2 45 ? 20.846 4.382 28.200 1.00 53.86 ? 215 LEU B CA 1 ATOM 1586 C C . LEU B 2 45 ? 20.034 4.653 26.936 1.00 51.91 ? 215 LEU B C 1 ATOM 1587 O O . LEU B 2 45 ? 19.672 5.795 26.661 1.00 52.47 ? 215 LEU B O 1 ATOM 1588 C CB . LEU B 2 45 ? 22.349 4.427 27.868 1.00 54.57 ? 215 LEU B CB 1 ATOM 1589 C CG . LEU B 2 45 ? 23.323 5.281 28.700 1.00 55.99 ? 215 LEU B CG 1 ATOM 1590 C CD1 . LEU B 2 45 ? 23.119 6.774 28.434 1.00 55.77 ? 215 LEU B CD1 1 ATOM 1591 C CD2 . LEU B 2 45 ? 23.276 4.985 30.210 1.00 56.75 ? 215 LEU B CD2 1 ATOM 1592 N N . LEU B 2 46 ? 19.755 3.602 26.173 1.00 49.83 ? 216 LEU B N 1 ATOM 1593 C CA . LEU B 2 46 ? 19.237 3.756 24.813 1.00 48.81 ? 216 LEU B CA 1 ATOM 1594 C C . LEU B 2 46 ? 18.040 2.872 24.514 1.00 46.68 ? 216 LEU B C 1 ATOM 1595 O O . LEU B 2 46 ? 17.747 1.931 25.260 1.00 44.66 ? 216 LEU B O 1 ATOM 1596 C CB . LEU B 2 46 ? 20.343 3.458 23.795 1.00 49.46 ? 216 LEU B CB 1 ATOM 1597 C CG . LEU B 2 46 ? 21.374 4.561 23.570 1.00 51.51 ? 216 LEU B CG 1 ATOM 1598 C CD1 . LEU B 2 46 ? 22.750 3.972 23.262 1.00 52.19 ? 216 LEU B CD1 1 ATOM 1599 C CD2 . LEU B 2 46 ? 20.909 5.503 22.461 1.00 52.02 ? 216 LEU B CD2 1 ATOM 1600 N N . CYS B 2 47 ? 17.359 3.187 23.412 1.00 47.69 ? 217 CYS B N 1 ATOM 1601 C CA . CYS B 2 47 ? 16.298 2.335 22.866 1.00 48.63 ? 217 CYS B CA 1 ATOM 1602 C C . CYS B 2 47 ? 15.259 2.022 23.950 1.00 49.12 ? 217 CYS B C 1 ATOM 1603 O O . CYS B 2 47 ? 14.649 0.949 23.965 1.00 48.67 ? 217 CYS B O 1 ATOM 1604 C CB . CYS B 2 47 ? 16.920 1.062 22.256 1.00 48.15 ? 217 CYS B CB 1 ATOM 1605 S SG . CYS B 2 47 ? 15.803 -0.037 21.383 1.00 49.57 ? 217 CYS B SG 1 ATOM 1606 N N . GLU B 2 48 ? 15.073 2.995 24.846 1.00 51.35 ? 218 GLU B N 1 ATOM 1607 C CA . GLU B 2 48 ? 14.258 2.859 26.058 1.00 53.42 ? 218 GLU B CA 1 ATOM 1608 C C . GLU B 2 48 ? 12.775 2.663 25.714 1.00 52.44 ? 218 GLU B C 1 ATOM 1609 O O . GLU B 2 48 ? 12.031 2.067 26.493 1.00 51.12 ? 218 GLU B O 1 ATOM 1610 C CB . GLU B 2 48 ? 14.446 4.079 26.991 1.00 55.11 ? 218 GLU B CB 1 ATOM 1611 C CG . GLU B 2 48 ? 15.912 4.439 27.352 1.00 56.35 ? 218 GLU B CG 1 ATOM 1612 C CD . GLU B 2 48 ? 16.058 5.750 28.169 1.00 57.35 ? 218 GLU B CD 1 ATOM 1613 O OE1 . GLU B 2 48 ? 16.430 6.796 27.577 1.00 58.30 ? 218 GLU B OE1 1 ATOM 1614 O OE2 . GLU B 2 48 ? 15.809 5.737 29.402 1.00 57.96 ? 218 GLU B OE2 1 ATOM 1615 N N . ASP B 2 49 ? 12.370 3.150 24.538 1.00 51.51 ? 219 ASP B N 1 ATOM 1616 C CA . ASP B 2 49 ? 11.000 3.012 24.052 1.00 51.85 ? 219 ASP B CA 1 ATOM 1617 C C . ASP B 2 49 ? 10.917 2.049 22.870 1.00 51.83 ? 219 ASP B C 1 ATOM 1618 O O . ASP B 2 49 ? 10.026 2.165 22.013 1.00 51.86 ? 219 ASP B O 1 ATOM 1619 C CB . ASP B 2 49 ? 10.439 4.382 23.654 1.00 53.55 ? 219 ASP B CB 1 ATOM 1620 C CG . ASP B 2 49 ? 10.275 5.315 24.843 1.00 54.48 ? 219 ASP B CG 1 ATOM 1621 O OD1 . ASP B 2 49 ? 9.468 5.002 25.749 1.00 53.86 ? 219 ASP B OD1 1 ATOM 1622 O OD2 . ASP B 2 49 ? 10.965 6.360 24.870 1.00 55.02 ? 219 ASP B OD2 1 ATOM 1623 N N . GLY B 2 50 ? 11.851 1.101 22.823 1.00 50.12 ? 220 GLY B N 1 ATOM 1624 C CA . GLY B 2 50 ? 11.886 0.105 21.764 1.00 46.46 ? 220 GLY B CA 1 ATOM 1625 C C . GLY B 2 50 ? 12.471 0.631 20.469 1.00 44.57 ? 220 GLY B C 1 ATOM 1626 O O . GLY B 2 50 ? 12.269 1.787 20.106 1.00 44.58 ? 220 GLY B O 1 ATOM 1627 N N . CYS B 2 51 ? 13.209 -0.230 19.778 1.00 42.51 ? 221 CYS B N 1 ATOM 1628 C CA . CYS B 2 51 ? 13.734 0.068 18.450 1.00 41.25 ? 221 CYS B CA 1 ATOM 1629 C C . CYS B 2 51 ? 13.922 -1.243 17.682 1.00 38.12 ? 221 CYS B C 1 ATOM 1630 O O . CYS B 2 51 ? 13.538 -2.295 18.174 1.00 37.29 ? 221 CYS B O 1 ATOM 1631 C CB . CYS B 2 51 ? 15.038 0.869 18.545 1.00 43.24 ? 221 CYS B CB 1 ATOM 1632 S SG . CYS B 2 51 ? 16.387 0.068 19.422 1.00 47.22 ? 221 CYS B SG 1 ATOM 1633 N N . LEU B 2 52 ? 14.497 -1.172 16.484 1.00 36.66 ? 222 LEU B N 1 ATOM 1634 C CA . LEU B 2 52 ? 14.680 -2.351 15.628 1.00 36.90 ? 222 LEU B CA 1 ATOM 1635 C C . LEU B 2 52 ? 16.119 -2.866 15.644 1.00 37.83 ? 222 LEU B C 1 ATOM 1636 O O . LEU B 2 52 ? 17.081 -2.083 15.756 1.00 38.79 ? 222 LEU B O 1 ATOM 1637 C CB . LEU B 2 52 ? 14.286 -2.050 14.179 1.00 35.85 ? 222 LEU B CB 1 ATOM 1638 C CG . LEU B 2 52 ? 12.964 -1.330 13.884 1.00 35.87 ? 222 LEU B CG 1 ATOM 1639 C CD1 . LEU B 2 52 ? 13.041 -0.579 12.563 1.00 34.27 ? 222 LEU B CD1 1 ATOM 1640 C CD2 . LEU B 2 52 ? 11.794 -2.294 13.891 1.00 34.79 ? 222 LEU B CD2 1 ATOM 1641 N N . ALA B 2 53 ? 16.251 -4.186 15.515 1.00 34.29 ? 223 ALA B N 1 ATOM 1642 C CA . ALA B 2 53 ? 17.539 -4.836 15.423 1.00 31.31 ? 223 ALA B CA 1 ATOM 1643 C C . ALA B 2 53 ? 17.573 -5.819 14.239 1.00 30.89 ? 223 ALA B C 1 ATOM 1644 O O . ALA B 2 53 ? 16.725 -6.714 14.109 1.00 28.92 ? 223 ALA B O 1 ATOM 1645 C CB . ALA B 2 53 ? 17.868 -5.540 16.730 1.00 29.35 ? 223 ALA B CB 1 ATOM 1646 N N . LEU B 2 54 ? 18.554 -5.622 13.368 1.00 29.96 ? 224 LEU B N 1 ATOM 1647 C CA . LEU B 2 54 ? 18.756 -6.484 12.220 1.00 29.33 ? 224 LEU B CA 1 ATOM 1648 C C . LEU B 2 54 ? 19.792 -7.531 12.596 1.00 26.89 ? 224 LEU B C 1 ATOM 1649 O O . LEU B 2 54 ? 20.887 -7.201 13.045 1.00 27.83 ? 224 LEU B O 1 ATOM 1650 C CB . LEU B 2 54 ? 19.234 -5.660 11.016 1.00 29.73 ? 224 LEU B CB 1 ATOM 1651 C CG . LEU B 2 54 ? 19.366 -6.375 9.667 1.00 30.86 ? 224 LEU B CG 1 ATOM 1652 C CD1 . LEU B 2 54 ? 17.990 -6.698 9.070 1.00 29.16 ? 224 LEU B CD1 1 ATOM 1653 C CD2 . LEU B 2 54 ? 20.214 -5.564 8.677 1.00 30.57 ? 224 LEU B CD2 1 ATOM 1654 N N . VAL B 2 55 ? 19.460 -8.798 12.427 1.00 24.55 ? 225 VAL B N 1 ATOM 1655 C CA . VAL B 2 55 ? 20.441 -9.821 12.754 1.00 25.63 ? 225 VAL B CA 1 ATOM 1656 C C . VAL B 2 55 ? 21.207 -10.174 11.465 1.00 25.21 ? 225 VAL B C 1 ATOM 1657 O O . VAL B 2 55 ? 20.760 -10.988 10.660 1.00 26.18 ? 225 VAL B O 1 ATOM 1658 C CB . VAL B 2 55 ? 19.801 -11.004 13.525 1.00 24.14 ? 225 VAL B CB 1 ATOM 1659 C CG1 . VAL B 2 55 ? 20.854 -11.921 14.068 1.00 24.12 ? 225 VAL B CG1 1 ATOM 1660 C CG2 . VAL B 2 55 ? 18.960 -10.466 14.687 1.00 21.32 ? 225 VAL B CG2 1 ATOM 1661 N N . ASP B 2 56 ? 22.341 -9.497 11.281 1.00 27.31 ? 226 ASP B N 1 ATOM 1662 C CA . ASP B 2 56 ? 23.073 -9.434 10.002 1.00 29.09 ? 226 ASP B CA 1 ATOM 1663 C C . ASP B 2 56 ? 24.426 -10.141 10.043 1.00 28.20 ? 226 ASP B C 1 ATOM 1664 O O . ASP B 2 56 ? 25.449 -9.534 10.390 1.00 30.02 ? 226 ASP B O 1 ATOM 1665 C CB . ASP B 2 56 ? 23.271 -7.971 9.572 1.00 30.36 ? 226 ASP B CB 1 ATOM 1666 C CG . ASP B 2 56 ? 23.817 -7.836 8.157 1.00 34.22 ? 226 ASP B CG 1 ATOM 1667 O OD1 . ASP B 2 56 ? 24.440 -8.785 7.617 1.00 36.97 ? 226 ASP B OD1 1 ATOM 1668 O OD2 . ASP B 2 56 ? 23.644 -6.756 7.574 1.00 36.23 ? 226 ASP B OD2 1 ATOM 1669 N N . THR B 2 57 ? 24.428 -11.406 9.633 1.00 25.91 ? 227 THR B N 1 ATOM 1670 C CA . THR B 2 57 ? 25.627 -12.254 9.677 1.00 25.00 ? 227 THR B CA 1 ATOM 1671 C C . THR B 2 57 ? 26.748 -11.791 8.750 1.00 24.86 ? 227 THR B C 1 ATOM 1672 O O . THR B 2 57 ? 27.884 -12.237 8.884 1.00 23.03 ? 227 THR B O 1 ATOM 1673 C CB . THR B 2 57 ? 25.293 -13.687 9.283 1.00 24.53 ? 227 THR B CB 1 ATOM 1674 O OG1 . THR B 2 57 ? 24.790 -13.689 7.955 1.00 22.34 ? 227 THR B OG1 1 ATOM 1675 C CG2 . THR B 2 57 ? 24.253 -14.301 10.223 1.00 25.27 ? 227 THR B CG2 1 ATOM 1676 N N . GLY B 2 58 ? 26.412 -10.916 7.800 1.00 26.24 ? 228 GLY B N 1 ATOM 1677 C CA . GLY B 2 58 ? 27.379 -10.373 6.850 1.00 25.40 ? 228 GLY B CA 1 ATOM 1678 C C . GLY B 2 58 ? 27.973 -9.052 7.295 1.00 26.24 ? 228 GLY B C 1 ATOM 1679 O O . GLY B 2 58 ? 28.720 -8.424 6.549 1.00 27.29 ? 228 GLY B O 1 ATOM 1680 N N . ALA B 2 59 ? 27.616 -8.622 8.506 1.00 25.77 ? 229 ALA B N 1 ATOM 1681 C CA . ALA B 2 59 ? 28.237 -7.469 9.147 1.00 23.61 ? 229 ALA B CA 1 ATOM 1682 C C . ALA B 2 59 ? 29.262 -7.925 10.204 1.00 25.24 ? 229 ALA B C 1 ATOM 1683 O O . ALA B 2 59 ? 29.057 -8.922 10.917 1.00 26.17 ? 229 ALA B O 1 ATOM 1684 C CB . ALA B 2 59 ? 27.188 -6.573 9.755 1.00 21.05 ? 229 ALA B CB 1 ATOM 1685 N N . SER B 2 60 ? 30.369 -7.198 10.277 1.00 24.84 ? 230 SER B N 1 ATOM 1686 C CA . SER B 2 60 ? 31.455 -7.499 11.192 1.00 26.30 ? 230 SER B CA 1 ATOM 1687 C C . SER B 2 60 ? 31.151 -7.054 12.616 1.00 28.69 ? 230 SER B C 1 ATOM 1688 O O . SER B 2 60 ? 31.566 -7.712 13.576 1.00 29.92 ? 230 SER B O 1 ATOM 1689 C CB . SER B 2 60 ? 32.714 -6.772 10.737 1.00 26.13 ? 230 SER B CB 1 ATOM 1690 O OG . SER B 2 60 ? 32.899 -6.924 9.355 1.00 23.38 ? 230 SER B OG 1 ATOM 1691 N N . TYR B 2 61 ? 30.430 -5.943 12.742 1.00 30.24 ? 231 TYR B N 1 ATOM 1692 C CA . TYR B 2 61 ? 30.253 -5.272 14.025 1.00 33.17 ? 231 TYR B CA 1 ATOM 1693 C C . TYR B 2 61 ? 28.789 -5.185 14.483 1.00 34.17 ? 231 TYR B C 1 ATOM 1694 O O . TYR B 2 61 ? 27.861 -5.613 13.782 1.00 32.82 ? 231 TYR B O 1 ATOM 1695 C CB . TYR B 2 61 ? 30.858 -3.863 13.967 1.00 35.91 ? 231 TYR B CB 1 ATOM 1696 C CG . TYR B 2 61 ? 32.252 -3.782 13.363 1.00 36.65 ? 231 TYR B CG 1 ATOM 1697 C CD1 . TYR B 2 61 ? 33.335 -4.431 13.956 1.00 36.42 ? 231 TYR B CD1 1 ATOM 1698 C CD2 . TYR B 2 61 ? 32.485 -3.041 12.201 1.00 37.42 ? 231 TYR B CD2 1 ATOM 1699 C CE1 . TYR B 2 61 ? 34.620 -4.356 13.404 1.00 36.75 ? 231 TYR B CE1 1 ATOM 1700 C CE2 . TYR B 2 61 ? 33.768 -2.950 11.639 1.00 37.99 ? 231 TYR B CE2 1 ATOM 1701 C CZ . TYR B 2 61 ? 34.833 -3.609 12.248 1.00 37.89 ? 231 TYR B CZ 1 ATOM 1702 O OH . TYR B 2 61 ? 36.104 -3.525 11.692 1.00 38.23 ? 231 TYR B OH 1 ATOM 1703 N N . ILE B 2 62 ? 28.598 -4.664 15.691 1.00 34.48 ? 232 ILE B N 1 ATOM 1704 C CA . ILE B 2 62 ? 27.292 -4.182 16.105 1.00 33.70 ? 232 ILE B CA 1 ATOM 1705 C C . ILE B 2 62 ? 27.213 -2.742 15.606 1.00 34.25 ? 232 ILE B C 1 ATOM 1706 O O . ILE B 2 62 ? 28.131 -1.958 15.815 1.00 33.57 ? 232 ILE B O 1 ATOM 1707 C CB . ILE B 2 62 ? 27.116 -4.251 17.620 1.00 32.84 ? 232 ILE B CB 1 ATOM 1708 C CG1 . ILE B 2 62 ? 27.080 -5.712 18.076 1.00 31.90 ? 232 ILE B CG1 1 ATOM 1709 C CG2 . ILE B 2 62 ? 25.837 -3.516 18.049 1.00 35.59 ? 232 ILE B CG2 1 ATOM 1710 C CD1 . ILE B 2 62 ? 26.995 -5.892 19.560 1.00 30.84 ? 232 ILE B CD1 1 ATOM 1711 N N . SER B 2 63 ? 26.148 -2.402 14.898 1.00 34.94 ? 233 SER B N 1 ATOM 1712 C CA . SER B 2 63 ? 26.012 -1.025 14.453 1.00 36.86 ? 233 SER B CA 1 ATOM 1713 C C . SER B 2 63 ? 24.744 -0.382 14.986 1.00 37.63 ? 233 SER B C 1 ATOM 1714 O O . SER B 2 63 ? 23.750 -1.058 15.253 1.00 40.83 ? 233 SER B O 1 ATOM 1715 C CB . SER B 2 63 ? 26.110 -0.907 12.932 1.00 36.93 ? 233 SER B CB 1 ATOM 1716 O OG . SER B 2 63 ? 24.886 -1.230 12.311 1.00 38.76 ? 233 SER B OG 1 ATOM 1717 N N . GLY B 2 64 ? 24.802 0.924 15.179 1.00 36.72 ? 234 GLY B N 1 ATOM 1718 C CA . GLY B 2 64 ? 23.623 1.690 15.507 1.00 36.40 ? 234 GLY B CA 1 ATOM 1719 C C . GLY B 2 64 ? 23.634 2.930 14.650 1.00 37.97 ? 234 GLY B C 1 ATOM 1720 O O . GLY B 2 64 ? 24.581 3.167 13.890 1.00 36.75 ? 234 GLY B O 1 ATOM 1721 N N . SER B 2 65 ? 22.569 3.717 14.757 1.00 40.13 ? 235 SER B N 1 ATOM 1722 C CA . SER B 2 65 ? 22.517 5.025 14.123 1.00 41.07 ? 235 SER B CA 1 ATOM 1723 C C . SER B 2 65 ? 23.574 5.943 14.736 1.00 41.88 ? 235 SER B C 1 ATOM 1724 O O . SER B 2 65 ? 23.928 5.801 15.903 1.00 42.49 ? 235 SER B O 1 ATOM 1725 C CB . SER B 2 65 ? 21.129 5.639 14.300 1.00 41.50 ? 235 SER B CB 1 ATOM 1726 O OG . SER B 2 65 ? 20.719 5.589 15.660 1.00 41.23 ? 235 SER B OG 1 ATOM 1727 N N . THR B 2 66 ? 24.065 6.883 13.937 1.00 43.21 ? 236 THR B N 1 ATOM 1728 C CA . THR B 2 66 ? 25.029 7.887 14.378 1.00 45.23 ? 236 THR B CA 1 ATOM 1729 C C . THR B 2 66 ? 24.695 8.518 15.740 1.00 46.98 ? 236 THR B C 1 ATOM 1730 O O . THR B 2 66 ? 25.574 8.656 16.585 1.00 48.95 ? 236 THR B O 1 ATOM 1731 C CB . THR B 2 66 ? 25.199 8.978 13.293 1.00 45.84 ? 236 THR B CB 1 ATOM 1732 O OG1 . THR B 2 66 ? 25.616 8.365 12.063 1.00 45.10 ? 236 THR B OG1 1 ATOM 1733 C CG2 . THR B 2 66 ? 26.225 10.046 13.715 1.00 45.40 ? 236 THR B CG2 1 ATOM 1734 N N . SER B 2 67 ? 23.436 8.887 15.960 1.00 47.73 ? 237 SER B N 1 ATOM 1735 C CA . SER B 2 67 ? 23.038 9.474 17.236 1.00 48.37 ? 237 SER B CA 1 ATOM 1736 C C . SER B 2 67 ? 23.179 8.488 18.390 1.00 47.70 ? 237 SER B C 1 ATOM 1737 O O . SER B 2 67 ? 23.750 8.816 19.426 1.00 48.93 ? 237 SER B O 1 ATOM 1738 C CB . SER B 2 67 ? 21.620 10.061 17.175 1.00 50.16 ? 237 SER B CB 1 ATOM 1739 O OG . SER B 2 67 ? 20.776 9.342 16.283 1.00 52.37 ? 237 SER B OG 1 ATOM 1740 N N . SER B 2 68 ? 22.687 7.272 18.195 1.00 46.97 ? 238 SER B N 1 ATOM 1741 C CA . SER B 2 68 ? 22.727 6.252 19.241 1.00 45.72 ? 238 SER B CA 1 ATOM 1742 C C . SER B 2 68 ? 24.154 5.865 19.624 1.00 44.51 ? 238 SER B C 1 ATOM 1743 O O . SER B 2 68 ? 24.439 5.629 20.797 1.00 44.49 ? 238 SER B O 1 ATOM 1744 C CB . SER B 2 68 ? 21.950 5.007 18.815 1.00 45.21 ? 238 SER B CB 1 ATOM 1745 O OG . SER B 2 68 ? 20.706 5.350 18.233 1.00 46.07 ? 238 SER B OG 1 ATOM 1746 N N . ILE B 2 69 ? 25.038 5.797 18.634 1.00 43.20 ? 239 ILE B N 1 ATOM 1747 C CA . ILE B 2 69 ? 26.418 5.390 18.863 1.00 43.15 ? 239 ILE B CA 1 ATOM 1748 C C . ILE B 2 69 ? 27.242 6.528 19.471 1.00 45.69 ? 239 ILE B C 1 ATOM 1749 O O . ILE B 2 69 ? 28.043 6.278 20.378 1.00 45.20 ? 239 ILE B O 1 ATOM 1750 C CB . ILE B 2 69 ? 27.074 4.788 17.584 1.00 42.08 ? 239 ILE B CB 1 ATOM 1751 C CG1 . ILE B 2 69 ? 26.368 3.488 17.170 1.00 41.51 ? 239 ILE B CG1 1 ATOM 1752 C CG2 . ILE B 2 69 ? 28.578 4.554 17.764 1.00 40.69 ? 239 ILE B CG2 1 ATOM 1753 C CD1 . ILE B 2 69 ? 26.130 2.479 18.303 1.00 41.32 ? 239 ILE B CD1 1 ATOM 1754 N N . GLU B 2 70 ? 27.035 7.765 19.000 1.00 46.74 ? 240 GLU B N 1 ATOM 1755 C CA . GLU B 2 70 ? 27.609 8.948 19.665 1.00 49.99 ? 240 GLU B CA 1 ATOM 1756 C C . GLU B 2 70 ? 27.366 8.871 21.169 1.00 48.73 ? 240 GLU B C 1 ATOM 1757 O O . GLU B 2 70 ? 28.265 9.124 21.971 1.00 49.39 ? 240 GLU B O 1 ATOM 1758 C CB . GLU B 2 70 ? 26.996 10.248 19.125 1.00 51.36 ? 240 GLU B CB 1 ATOM 1759 C CG . GLU B 2 70 ? 27.608 10.750 17.823 1.00 54.58 ? 240 GLU B CG 1 ATOM 1760 C CD . GLU B 2 70 ? 26.734 11.768 17.093 1.00 55.39 ? 240 GLU B CD 1 ATOM 1761 O OE1 . GLU B 2 70 ? 27.283 12.522 16.256 1.00 57.48 ? 240 GLU B OE1 1 ATOM 1762 O OE2 . GLU B 2 70 ? 25.504 11.817 17.342 1.00 58.03 ? 240 GLU B OE2 1 ATOM 1763 N N . LYS B 2 71 ? 26.138 8.499 21.525 1.00 47.95 ? 241 LYS B N 1 ATOM 1764 C CA . LYS B 2 71 ? 25.679 8.412 22.899 1.00 47.20 ? 241 LYS B CA 1 ATOM 1765 C C . LYS B 2 71 ? 26.272 7.201 23.598 1.00 46.84 ? 241 LYS B C 1 ATOM 1766 O O . LYS B 2 71 ? 26.647 7.283 24.764 1.00 47.44 ? 241 LYS B O 1 ATOM 1767 C CB . LYS B 2 71 ? 24.164 8.297 22.897 1.00 48.59 ? 241 LYS B CB 1 ATOM 1768 C CG . LYS B 2 71 ? 23.450 9.083 23.961 1.00 51.04 ? 241 LYS B CG 1 ATOM 1769 C CD . LYS B 2 71 ? 21.999 9.297 23.528 1.00 53.87 ? 241 LYS B CD 1 ATOM 1770 C CE . LYS B 2 71 ? 21.922 10.026 22.171 1.00 55.21 ? 241 LYS B CE 1 ATOM 1771 N NZ . LYS B 2 71 ? 20.587 9.910 21.509 1.00 56.10 ? 241 LYS B NZ 1 ATOM 1772 N N . LEU B 2 72 ? 26.338 6.073 22.890 1.00 46.18 ? 242 LEU B N 1 ATOM 1773 C CA . LEU B 2 72 ? 26.897 4.846 23.446 1.00 45.52 ? 242 LEU B CA 1 ATOM 1774 C C . LEU B 2 72 ? 28.358 5.079 23.805 1.00 44.28 ? 242 LEU B C 1 ATOM 1775 O O . LEU B 2 72 ? 28.807 4.726 24.903 1.00 41.43 ? 242 LEU B O 1 ATOM 1776 C CB . LEU B 2 72 ? 26.771 3.688 22.451 1.00 46.12 ? 242 LEU B CB 1 ATOM 1777 C CG . LEU B 2 72 ? 27.353 2.322 22.854 1.00 47.37 ? 242 LEU B CG 1 ATOM 1778 C CD1 . LEU B 2 72 ? 26.655 1.754 24.088 1.00 47.49 ? 242 LEU B CD1 1 ATOM 1779 C CD2 . LEU B 2 72 ? 27.283 1.314 21.710 1.00 46.41 ? 242 LEU B CD2 1 ATOM 1780 N N . MET B 2 73 ? 29.072 5.697 22.866 1.00 44.23 ? 243 MET B N 1 ATOM 1781 C CA . MET B 2 73 ? 30.497 5.953 22.983 1.00 45.02 ? 243 MET B CA 1 ATOM 1782 C C . MET B 2 73 ? 30.822 7.041 24.010 1.00 46.00 ? 243 MET B C 1 ATOM 1783 O O . MET B 2 73 ? 31.810 6.932 24.730 1.00 45.18 ? 243 MET B O 1 ATOM 1784 C CB . MET B 2 73 ? 31.074 6.294 21.614 1.00 44.54 ? 243 MET B CB 1 ATOM 1785 C CG . MET B 2 73 ? 31.025 5.140 20.616 1.00 44.27 ? 243 MET B CG 1 ATOM 1786 S SD . MET B 2 73 ? 31.839 3.614 21.147 1.00 45.48 ? 243 MET B SD 1 ATOM 1787 C CE . MET B 2 73 ? 31.596 2.589 19.690 1.00 44.90 ? 243 MET B CE 1 ATOM 1788 N N . GLU B 2 74 ? 29.985 8.076 24.073 1.00 48.46 ? 244 GLU B N 1 ATOM 1789 C CA . GLU B 2 74 ? 30.064 9.094 25.126 1.00 50.10 ? 244 GLU B CA 1 ATOM 1790 C C . GLU B 2 74 ? 30.094 8.442 26.495 1.00 48.76 ? 244 GLU B C 1 ATOM 1791 O O . GLU B 2 74 ? 30.818 8.883 27.384 1.00 49.30 ? 244 GLU B O 1 ATOM 1792 C CB . GLU B 2 74 ? 28.873 10.050 25.044 1.00 53.70 ? 244 GLU B CB 1 ATOM 1793 C CG . GLU B 2 74 ? 29.233 11.509 24.789 1.00 58.50 ? 244 GLU B CG 1 ATOM 1794 C CD . GLU B 2 74 ? 29.225 12.341 26.068 1.00 62.04 ? 244 GLU B CD 1 ATOM 1795 O OE1 . GLU B 2 74 ? 28.580 13.418 26.083 1.00 63.38 ? 244 GLU B OE1 1 ATOM 1796 O OE2 . GLU B 2 74 ? 29.846 11.911 27.068 1.00 63.83 ? 244 GLU B OE2 1 ATOM 1797 N N . ALA B 2 75 ? 29.310 7.379 26.644 1.00 46.83 ? 245 ALA B N 1 ATOM 1798 C CA . ALA B 2 75 ? 29.193 6.663 27.895 1.00 45.67 ? 245 ALA B CA 1 ATOM 1799 C C . ALA B 2 75 ? 30.385 5.749 28.136 1.00 46.70 ? 245 ALA B C 1 ATOM 1800 O O . ALA B 2 75 ? 30.669 5.388 29.275 1.00 48.56 ? 245 ALA B O 1 ATOM 1801 C CB . ALA B 2 75 ? 27.901 5.873 27.919 1.00 44.87 ? 245 ALA B CB 1 ATOM 1802 N N . LEU B 2 76 ? 31.073 5.368 27.062 1.00 47.75 ? 246 LEU B N 1 ATOM 1803 C CA . LEU B 2 76 ? 32.237 4.483 27.155 1.00 48.70 ? 246 LEU B CA 1 ATOM 1804 C C . LEU B 2 76 ? 33.550 5.270 27.191 1.00 50.13 ? 246 LEU B C 1 ATOM 1805 O O . LEU B 2 76 ? 34.620 4.699 27.415 1.00 50.66 ? 246 LEU B O 1 ATOM 1806 C CB . LEU B 2 76 ? 32.242 3.452 26.009 1.00 47.24 ? 246 LEU B CB 1 ATOM 1807 C CG . LEU B 2 76 ? 31.025 2.512 25.907 1.00 45.84 ? 246 LEU B CG 1 ATOM 1808 C CD1 . LEU B 2 76 ? 31.058 1.692 24.639 1.00 45.06 ? 246 LEU B CD1 1 ATOM 1809 C CD2 . LEU B 2 76 ? 30.908 1.599 27.101 1.00 45.51 ? 246 LEU B CD2 1 ATOM 1810 N N . GLY B 2 77 ? 33.459 6.581 26.977 1.00 50.81 ? 247 GLY B N 1 ATOM 1811 C CA . GLY B 2 77 ? 34.635 7.451 26.963 1.00 52.44 ? 247 GLY B CA 1 ATOM 1812 C C . GLY B 2 77 ? 35.450 7.313 25.692 1.00 54.14 ? 247 GLY B C 1 ATOM 1813 O O . GLY B 2 77 ? 36.545 7.868 25.585 1.00 53.70 ? 247 GLY B O 1 ATOM 1814 N N . ALA B 2 78 ? 34.900 6.576 24.728 1.00 55.36 ? 248 ALA B N 1 ATOM 1815 C CA . ALA B 2 78 ? 35.560 6.291 23.464 1.00 57.07 ? 248 ALA B CA 1 ATOM 1816 C C . ALA B 2 78 ? 35.649 7.530 22.586 1.00 58.41 ? 248 ALA B C 1 ATOM 1817 O O . ALA B 2 78 ? 34.721 8.333 22.554 1.00 59.92 ? 248 ALA B O 1 ATOM 1818 C CB . ALA B 2 78 ? 34.827 5.187 22.743 1.00 57.17 ? 248 ALA B CB 1 ATOM 1819 N N . LYS B 2 79 ? 36.765 7.675 21.878 1.00 59.63 ? 249 LYS B N 1 ATOM 1820 C CA . LYS B 2 79 ? 37.012 8.849 21.041 1.00 62.18 ? 249 LYS B CA 1 ATOM 1821 C C . LYS B 2 79 ? 36.726 8.539 19.583 1.00 62.85 ? 249 LYS B C 1 ATOM 1822 O O . LYS B 2 79 ? 37.176 7.523 19.055 1.00 63.28 ? 249 LYS B O 1 ATOM 1823 C CB . LYS B 2 79 ? 38.465 9.326 21.169 1.00 62.51 ? 249 LYS B CB 1 ATOM 1824 C CG . LYS B 2 79 ? 38.922 9.666 22.582 1.00 63.09 ? 249 LYS B CG 1 ATOM 1825 C CD . LYS B 2 79 ? 40.454 9.754 22.661 1.00 63.73 ? 249 LYS B CD 1 ATOM 1826 C CE . LYS B 2 79 ? 40.989 11.145 22.272 1.00 64.12 ? 249 LYS B CE 1 ATOM 1827 N NZ . LYS B 2 79 ? 40.834 12.151 23.376 1.00 63.65 ? 249 LYS B NZ 1 ATOM 1828 N N . LYS B 2 80 ? 35.985 9.427 18.935 1.00 64.22 ? 250 LYS B N 1 ATOM 1829 C CA . LYS B 2 80 ? 35.696 9.293 17.519 1.00 67.07 ? 250 LYS B CA 1 ATOM 1830 C C . LYS B 2 80 ? 36.939 9.588 16.676 1.00 68.44 ? 250 LYS B C 1 ATOM 1831 O O . LYS B 2 80 ? 37.485 10.694 16.721 1.00 68.82 ? 250 LYS B O 1 ATOM 1832 C CB . LYS B 2 80 ? 34.551 10.231 17.126 1.00 68.42 ? 250 LYS B CB 1 ATOM 1833 C CG . LYS B 2 80 ? 33.907 9.914 15.788 1.00 70.19 ? 250 LYS B CG 1 ATOM 1834 C CD . LYS B 2 80 ? 32.700 10.800 15.536 1.00 71.56 ? 250 LYS B CD 1 ATOM 1835 C CE . LYS B 2 80 ? 32.206 10.673 14.097 1.00 72.91 ? 250 LYS B CE 1 ATOM 1836 N NZ . LYS B 2 80 ? 33.103 11.377 13.133 1.00 73.43 ? 250 LYS B NZ 1 ATOM 1837 N N . ARG B 2 81 ? 37.397 8.580 15.937 1.00 69.56 ? 251 ARG B N 1 ATOM 1838 C CA . ARG B 2 81 ? 38.364 8.779 14.863 1.00 70.99 ? 251 ARG B CA 1 ATOM 1839 C C . ARG B 2 81 ? 37.569 9.017 13.580 1.00 72.63 ? 251 ARG B C 1 ATOM 1840 O O . ARG B 2 81 ? 36.358 9.249 13.632 1.00 73.76 ? 251 ARG B O 1 ATOM 1841 C CB . ARG B 2 81 ? 39.240 7.542 14.689 1.00 70.48 ? 251 ARG B CB 1 ATOM 1842 C CG . ARG B 2 81 ? 40.467 7.437 15.571 1.00 70.18 ? 251 ARG B CG 1 ATOM 1843 C CD . ARG B 2 81 ? 40.936 5.995 15.516 1.00 70.14 ? 251 ARG B CD 1 ATOM 1844 N NE . ARG B 2 81 ? 42.374 5.803 15.671 1.00 70.34 ? 251 ARG B NE 1 ATOM 1845 C CZ . ARG B 2 81 ? 43.002 4.657 15.411 1.00 70.23 ? 251 ARG B CZ 1 ATOM 1846 N NH1 . ARG B 2 81 ? 42.320 3.602 14.977 1.00 69.44 ? 251 ARG B NH1 1 ATOM 1847 N NH2 . ARG B 2 81 ? 44.316 4.562 15.576 1.00 70.36 ? 251 ARG B NH2 1 ATOM 1848 N N . LEU B 2 82 ? 38.234 8.955 12.429 1.00 73.62 ? 252 LEU B N 1 ATOM 1849 C CA . LEU B 2 82 ? 37.541 9.159 11.162 1.00 73.88 ? 252 LEU B CA 1 ATOM 1850 C C . LEU B 2 82 ? 36.458 8.100 10.962 1.00 73.50 ? 252 LEU B C 1 ATOM 1851 O O . LEU B 2 82 ? 35.288 8.441 10.769 1.00 74.89 ? 252 LEU B O 1 ATOM 1852 C CB . LEU B 2 82 ? 38.523 9.192 9.976 1.00 74.54 ? 252 LEU B CB 1 ATOM 1853 C CG . LEU B 2 82 ? 37.984 9.415 8.548 1.00 74.43 ? 252 LEU B CG 1 ATOM 1854 C CD1 . LEU B 2 82 ? 37.033 10.615 8.434 1.00 74.90 ? 252 LEU B CD1 1 ATOM 1855 C CD2 . LEU B 2 82 ? 39.122 9.539 7.546 1.00 74.04 ? 252 LEU B CD2 1 ATOM 1856 N N . PHE B 2 83 ? 36.847 6.828 11.044 1.00 71.41 ? 253 PHE B N 1 ATOM 1857 C CA . PHE B 2 83 ? 35.944 5.724 10.733 1.00 69.87 ? 253 PHE B CA 1 ATOM 1858 C C . PHE B 2 83 ? 35.402 5.041 11.982 1.00 68.13 ? 253 PHE B C 1 ATOM 1859 O O . PHE B 2 83 ? 34.198 4.799 12.097 1.00 68.28 ? 253 PHE B O 1 ATOM 1860 C CB . PHE B 2 83 ? 36.648 4.690 9.845 1.00 70.96 ? 253 PHE B CB 1 ATOM 1861 C CG . PHE B 2 83 ? 37.145 5.246 8.539 1.00 71.69 ? 253 PHE B CG 1 ATOM 1862 C CD1 . PHE B 2 83 ? 36.249 5.678 7.560 1.00 71.92 ? 253 PHE B CD1 1 ATOM 1863 C CD2 . PHE B 2 83 ? 38.511 5.328 8.281 1.00 72.14 ? 253 PHE B CD2 1 ATOM 1864 C CE1 . PHE B 2 83 ? 36.707 6.191 6.349 1.00 72.05 ? 253 PHE B CE1 1 ATOM 1865 C CE2 . PHE B 2 83 ? 38.980 5.839 7.073 1.00 72.32 ? 253 PHE B CE2 1 ATOM 1866 C CZ . PHE B 2 83 ? 38.075 6.272 6.105 1.00 72.14 ? 253 PHE B CZ 1 ATOM 1867 N N . ASP B 2 84 ? 36.305 4.748 12.913 1.00 64.93 ? 254 ASP B N 1 ATOM 1868 C CA . ASP B 2 84 ? 36.001 3.956 14.095 1.00 62.15 ? 254 ASP B CA 1 ATOM 1869 C C . ASP B 2 84 ? 36.049 4.772 15.391 1.00 59.46 ? 254 ASP B C 1 ATOM 1870 O O . ASP B 2 84 ? 36.383 5.957 15.388 1.00 59.27 ? 254 ASP B O 1 ATOM 1871 C CB . ASP B 2 84 ? 36.981 2.775 14.184 1.00 62.79 ? 254 ASP B CB 1 ATOM 1872 C CG . ASP B 2 84 ? 38.444 3.215 14.153 1.00 62.84 ? 254 ASP B CG 1 ATOM 1873 O OD1 . ASP B 2 84 ? 38.711 4.423 13.976 1.00 63.84 ? 254 ASP B OD1 1 ATOM 1874 O OD2 . ASP B 2 84 ? 39.333 2.352 14.294 1.00 62.03 ? 254 ASP B OD2 1 ATOM 1875 N N . TYR B 2 85 ? 35.697 4.117 16.491 1.00 56.19 ? 255 TYR B N 1 ATOM 1876 C CA . TYR B 2 85 ? 35.866 4.663 17.823 1.00 53.84 ? 255 TYR B CA 1 ATOM 1877 C C . TYR B 2 85 ? 36.982 3.902 18.545 1.00 53.00 ? 255 TYR B C 1 ATOM 1878 O O . TYR B 2 85 ? 37.128 2.684 18.383 1.00 52.53 ? 255 TYR B O 1 ATOM 1879 C CB . TYR B 2 85 ? 34.559 4.564 18.608 1.00 52.76 ? 255 TYR B CB 1 ATOM 1880 C CG . TYR B 2 85 ? 33.537 5.610 18.231 1.00 52.63 ? 255 TYR B CG 1 ATOM 1881 C CD1 . TYR B 2 85 ? 33.409 6.786 18.980 1.00 52.82 ? 255 TYR B CD1 1 ATOM 1882 C CD2 . TYR B 2 85 ? 32.692 5.431 17.131 1.00 52.21 ? 255 TYR B CD2 1 ATOM 1883 C CE1 . TYR B 2 85 ? 32.466 7.758 18.646 1.00 51.74 ? 255 TYR B CE1 1 ATOM 1884 C CE2 . TYR B 2 85 ? 31.750 6.401 16.781 1.00 51.68 ? 255 TYR B CE2 1 ATOM 1885 C CZ . TYR B 2 85 ? 31.644 7.559 17.544 1.00 52.34 ? 255 TYR B CZ 1 ATOM 1886 O OH . TYR B 2 85 ? 30.715 8.517 17.213 1.00 52.94 ? 255 TYR B OH 1 ATOM 1887 N N . VAL B 2 86 ? 37.777 4.623 19.333 1.00 51.36 ? 256 VAL B N 1 ATOM 1888 C CA . VAL B 2 86 ? 38.874 3.993 20.067 1.00 49.29 ? 256 VAL B CA 1 ATOM 1889 C C . VAL B 2 86 ? 38.867 4.323 21.549 1.00 49.52 ? 256 VAL B C 1 ATOM 1890 O O . VAL B 2 86 ? 38.246 5.300 21.980 1.00 50.37 ? 256 VAL B O 1 ATOM 1891 C CB . VAL B 2 86 ? 40.271 4.328 19.471 1.00 48.19 ? 256 VAL B CB 1 ATOM 1892 C CG1 . VAL B 2 86 ? 40.384 3.816 18.032 1.00 46.70 ? 256 VAL B CG1 1 ATOM 1893 C CG2 . VAL B 2 86 ? 40.579 5.829 19.571 1.00 47.32 ? 256 VAL B CG2 1 ATOM 1894 N N . VAL B 2 87 ? 39.546 3.474 22.316 1.00 48.85 ? 257 VAL B N 1 ATOM 1895 C CA . VAL B 2 87 ? 39.863 3.735 23.715 1.00 47.62 ? 257 VAL B CA 1 ATOM 1896 C C . VAL B 2 87 ? 41.358 3.512 23.956 1.00 48.44 ? 257 VAL B C 1 ATOM 1897 O O . VAL B 2 87 ? 42.019 2.754 23.225 1.00 48.04 ? 257 VAL B O 1 ATOM 1898 C CB . VAL B 2 87 ? 39.044 2.842 24.688 1.00 47.50 ? 257 VAL B CB 1 ATOM 1899 C CG1 . VAL B 2 87 ? 37.543 3.130 24.568 1.00 46.76 ? 257 VAL B CG1 1 ATOM 1900 C CG2 . VAL B 2 87 ? 39.347 1.359 24.476 1.00 46.96 ? 257 VAL B CG2 1 ATOM 1901 N N . LYS B 2 88 ? 41.892 4.190 24.966 1.00 48.41 ? 258 LYS B N 1 ATOM 1902 C CA . LYS B 2 88 ? 43.227 3.893 25.467 1.00 49.53 ? 258 LYS B CA 1 ATOM 1903 C C . LYS B 2 88 ? 43.243 2.429 25.903 1.00 47.45 ? 258 LYS B C 1 ATOM 1904 O O . LYS B 2 88 ? 42.395 2.008 26.697 1.00 47.04 ? 258 LYS B O 1 ATOM 1905 C CB . LYS B 2 88 ? 43.570 4.817 26.642 1.00 52.15 ? 258 LYS B CB 1 ATOM 1906 C CG . LYS B 2 88 ? 44.656 5.849 26.360 1.00 55.29 ? 258 LYS B CG 1 ATOM 1907 C CD . LYS B 2 88 ? 44.522 7.121 27.221 1.00 58.32 ? 258 LYS B CD 1 ATOM 1908 C CE . LYS B 2 88 ? 43.792 6.895 28.571 1.00 59.98 ? 258 LYS B CE 1 ATOM 1909 N NZ . LYS B 2 88 ? 44.500 5.990 29.533 1.00 60.31 ? 258 LYS B NZ 1 ATOM 1910 N N . CYS B 2 89 ? 44.192 1.659 25.374 1.00 45.10 ? 259 CYS B N 1 ATOM 1911 C CA . CYS B 2 89 ? 44.185 0.201 25.533 1.00 43.52 ? 259 CYS B CA 1 ATOM 1912 C C . CYS B 2 89 ? 44.121 -0.287 26.973 1.00 43.46 ? 259 CYS B C 1 ATOM 1913 O O . CYS B 2 89 ? 43.578 -1.363 27.237 1.00 43.57 ? 259 CYS B O 1 ATOM 1914 C CB . CYS B 2 89 ? 45.366 -0.435 24.811 1.00 43.46 ? 259 CYS B CB 1 ATOM 1915 S SG . CYS B 2 89 ? 45.233 -0.359 23.030 1.00 44.23 ? 259 CYS B SG 1 ATOM 1916 N N . ASN B 2 90 ? 44.659 0.511 27.894 1.00 43.36 ? 260 ASN B N 1 ATOM 1917 C CA . ASN B 2 90 ? 44.659 0.179 29.320 1.00 44.18 ? 260 ASN B CA 1 ATOM 1918 C C . ASN B 2 90 ? 43.275 0.239 29.984 1.00 43.85 ? 260 ASN B C 1 ATOM 1919 O O . ASN B 2 90 ? 43.035 -0.435 30.988 1.00 43.25 ? 260 ASN B O 1 ATOM 1920 C CB . ASN B 2 90 ? 45.629 1.091 30.073 1.00 44.93 ? 260 ASN B CB 1 ATOM 1921 C CG . ASN B 2 90 ? 45.205 2.540 30.032 1.00 45.04 ? 260 ASN B CG 1 ATOM 1922 O OD1 . ASN B 2 90 ? 44.952 3.097 28.962 1.00 46.17 ? 260 ASN B OD1 1 ATOM 1923 N ND2 . ASN B 2 90 ? 45.114 3.157 31.196 1.00 45.00 ? 260 ASN B ND2 1 ATOM 1924 N N . GLU B 2 91 ? 42.368 1.039 29.433 1.00 44.32 ? 261 GLU B N 1 ATOM 1925 C CA . GLU B 2 91 ? 41.009 1.097 29.981 1.00 46.67 ? 261 GLU B CA 1 ATOM 1926 C C . GLU B 2 91 ? 40.042 0.058 29.389 1.00 45.02 ? 261 GLU B C 1 ATOM 1927 O O . GLU B 2 91 ? 39.014 -0.250 29.996 1.00 44.90 ? 261 GLU B O 1 ATOM 1928 C CB . GLU B 2 91 ? 40.431 2.523 29.957 1.00 49.23 ? 261 GLU B CB 1 ATOM 1929 C CG . GLU B 2 91 ? 40.478 3.234 28.614 1.00 53.01 ? 261 GLU B CG 1 ATOM 1930 C CD . GLU B 2 91 ? 40.664 4.744 28.753 1.00 55.32 ? 261 GLU B CD 1 ATOM 1931 O OE1 . GLU B 2 91 ? 41.143 5.192 29.822 1.00 56.75 ? 261 GLU B OE1 1 ATOM 1932 O OE2 . GLU B 2 91 ? 40.347 5.480 27.788 1.00 55.91 ? 261 GLU B OE2 1 ATOM 1933 N N . GLY B 2 92 ? 40.399 -0.505 28.234 1.00 43.08 ? 262 GLY B N 1 ATOM 1934 C CA . GLY B 2 92 ? 39.642 -1.603 27.617 1.00 39.60 ? 262 GLY B CA 1 ATOM 1935 C C . GLY B 2 92 ? 39.066 -2.631 28.584 1.00 37.82 ? 262 GLY B C 1 ATOM 1936 O O . GLY B 2 92 ? 37.857 -2.824 28.615 1.00 39.41 ? 262 GLY B O 1 ATOM 1937 N N . PRO B 2 93 ? 39.919 -3.284 29.402 1.00 36.05 ? 263 PRO B N 1 ATOM 1938 C CA . PRO B 2 93 ? 39.422 -4.336 30.299 1.00 34.99 ? 263 PRO B CA 1 ATOM 1939 C C . PRO B 2 93 ? 38.489 -3.845 31.412 1.00 36.64 ? 263 PRO B C 1 ATOM 1940 O O . PRO B 2 93 ? 37.870 -4.667 32.101 1.00 37.52 ? 263 PRO B O 1 ATOM 1941 C CB . PRO B 2 93 ? 40.705 -4.909 30.917 1.00 34.25 ? 263 PRO B CB 1 ATOM 1942 C CG . PRO B 2 93 ? 41.809 -4.417 30.068 1.00 33.95 ? 263 PRO B CG 1 ATOM 1943 C CD . PRO B 2 93 ? 41.373 -3.101 29.546 1.00 33.89 ? 263 PRO B CD 1 ATOM 1944 N N . THR B 2 94 ? 38.404 -2.526 31.592 1.00 36.74 ? 264 THR B N 1 ATOM 1945 C CA . THR B 2 94 ? 37.539 -1.933 32.603 1.00 38.15 ? 264 THR B CA 1 ATOM 1946 C C . THR B 2 94 ? 36.252 -1.351 32.008 1.00 39.01 ? 264 THR B C 1 ATOM 1947 O O . THR B 2 94 ? 35.414 -0.803 32.732 1.00 39.32 ? 264 THR B O 1 ATOM 1948 C CB . THR B 2 94 ? 38.268 -0.842 33.433 1.00 39.56 ? 264 THR B CB 1 ATOM 1949 O OG1 . THR B 2 94 ? 38.619 0.266 32.591 1.00 40.49 ? 264 THR B OG1 1 ATOM 1950 C CG2 . THR B 2 94 ? 39.518 -1.405 34.097 1.00 39.87 ? 264 THR B CG2 1 ATOM 1951 N N . LEU B 2 95 ? 36.089 -1.469 30.695 1.00 38.84 ? 265 LEU B N 1 ATOM 1952 C CA . LEU B 2 95 ? 34.865 -1.015 30.063 1.00 38.96 ? 265 LEU B CA 1 ATOM 1953 C C . LEU B 2 95 ? 33.661 -1.824 30.559 1.00 37.67 ? 265 LEU B C 1 ATOM 1954 O O . LEU B 2 95 ? 33.782 -3.021 30.840 1.00 38.27 ? 265 LEU B O 1 ATOM 1955 C CB . LEU B 2 95 ? 34.976 -1.043 28.536 1.00 39.75 ? 265 LEU B CB 1 ATOM 1956 C CG . LEU B 2 95 ? 35.832 0.061 27.895 1.00 40.59 ? 265 LEU B CG 1 ATOM 1957 C CD1 . LEU B 2 95 ? 35.787 -0.044 26.378 1.00 39.56 ? 265 LEU B CD1 1 ATOM 1958 C CD2 . LEU B 2 95 ? 35.427 1.467 28.337 1.00 39.71 ? 265 LEU B CD2 1 ATOM 1959 N N . PRO B 2 96 ? 32.503 -1.163 30.692 1.00 35.86 ? 266 PRO B N 1 ATOM 1960 C CA . PRO B 2 96 ? 31.327 -1.836 31.224 1.00 36.17 ? 266 PRO B CA 1 ATOM 1961 C C . PRO B 2 96 ? 30.716 -2.821 30.237 1.00 35.86 ? 266 PRO B C 1 ATOM 1962 O O . PRO B 2 96 ? 30.894 -2.686 29.027 1.00 35.22 ? 266 PRO B O 1 ATOM 1963 C CB . PRO B 2 96 ? 30.347 -0.689 31.468 1.00 35.84 ? 266 PRO B CB 1 ATOM 1964 C CG . PRO B 2 96 ? 30.738 0.343 30.465 1.00 36.37 ? 266 PRO B CG 1 ATOM 1965 C CD . PRO B 2 96 ? 32.232 0.247 30.359 1.00 35.23 ? 266 PRO B CD 1 ATOM 1966 N N . ASP B 2 97 ? 30.022 -3.814 30.784 1.00 35.84 ? 267 ASP B N 1 ATOM 1967 C CA . ASP B 2 97 ? 29.160 -4.692 30.032 1.00 35.30 ? 267 ASP B CA 1 ATOM 1968 C C . ASP B 2 97 ? 28.184 -3.858 29.199 1.00 36.00 ? 267 ASP B C 1 ATOM 1969 O O . ASP B 2 97 ? 27.865 -2.717 29.550 1.00 35.33 ? 267 ASP B O 1 ATOM 1970 C CB . ASP B 2 97 ? 28.392 -5.590 31.003 1.00 34.66 ? 267 ASP B CB 1 ATOM 1971 C CG . ASP B 2 97 ? 29.270 -6.671 31.633 1.00 35.42 ? 267 ASP B CG 1 ATOM 1972 O OD1 . ASP B 2 97 ? 30.510 -6.667 31.436 1.00 34.92 ? 267 ASP B OD1 1 ATOM 1973 O OD2 . ASP B 2 97 ? 28.711 -7.543 32.333 1.00 36.58 ? 267 ASP B OD2 1 ATOM 1974 N N . ILE B 2 98 ? 27.746 -4.416 28.076 1.00 34.87 ? 268 ILE B N 1 ATOM 1975 C CA . ILE B 2 98 ? 26.699 -3.805 27.264 1.00 34.82 ? 268 ILE B CA 1 ATOM 1976 C C . ILE B 2 98 ? 25.647 -4.876 26.985 1.00 36.32 ? 268 ILE B C 1 ATOM 1977 O O . ILE B 2 98 ? 25.979 -6.003 26.598 1.00 36.40 ? 268 ILE B O 1 ATOM 1978 C CB . ILE B 2 98 ? 27.240 -3.192 25.948 1.00 34.02 ? 268 ILE B CB 1 ATOM 1979 C CG1 . ILE B 2 98 ? 28.306 -2.124 26.245 1.00 33.47 ? 268 ILE B CG1 1 ATOM 1980 C CG2 . ILE B 2 98 ? 26.093 -2.609 25.095 1.00 32.16 ? 268 ILE B CG2 1 ATOM 1981 C CD1 . ILE B 2 98 ? 29.060 -1.629 25.009 1.00 33.67 ? 268 ILE B CD1 1 ATOM 1982 N N . SER B 2 99 ? 24.383 -4.527 27.211 1.00 35.68 ? 269 SER B N 1 ATOM 1983 C CA . SER B 2 99 ? 23.308 -5.503 27.132 1.00 34.91 ? 269 SER B CA 1 ATOM 1984 C C . SER B 2 99 ? 22.258 -5.110 26.118 1.00 34.43 ? 269 SER B C 1 ATOM 1985 O O . SER B 2 99 ? 21.928 -3.941 25.965 1.00 33.98 ? 269 SER B O 1 ATOM 1986 C CB . SER B 2 99 ? 22.677 -5.731 28.499 1.00 34.72 ? 269 SER B CB 1 ATOM 1987 O OG . SER B 2 99 ? 23.528 -6.521 29.314 1.00 36.87 ? 269 SER B OG 1 ATOM 1988 N N . PHE B 2 100 ? 21.763 -6.109 25.403 1.00 34.50 ? 270 PHE B N 1 ATOM 1989 C CA . PHE B 2 100 ? 20.736 -5.894 24.401 1.00 33.94 ? 270 PHE B CA 1 ATOM 1990 C C . PHE B 2 100 ? 19.516 -6.673 24.844 1.00 34.08 ? 270 PHE B C 1 ATOM 1991 O O . PHE B 2 100 ? 19.596 -7.871 25.163 1.00 33.48 ? 270 PHE B O 1 ATOM 1992 C CB . PHE B 2 100 ? 21.243 -6.303 23.018 1.00 32.58 ? 270 PHE B CB 1 ATOM 1993 C CG . PHE B 2 100 ? 22.505 -5.588 22.617 1.00 31.80 ? 270 PHE B CG 1 ATOM 1994 C CD1 . PHE B 2 100 ? 22.452 -4.479 21.782 1.00 31.49 ? 270 PHE B CD1 1 ATOM 1995 C CD2 . PHE B 2 100 ? 23.742 -5.999 23.110 1.00 30.84 ? 270 PHE B CD2 1 ATOM 1996 C CE1 . PHE B 2 100 ? 23.599 -3.810 21.428 1.00 31.55 ? 270 PHE B CE1 1 ATOM 1997 C CE2 . PHE B 2 100 ? 24.898 -5.330 22.770 1.00 30.49 ? 270 PHE B CE2 1 ATOM 1998 C CZ . PHE B 2 100 ? 24.832 -4.237 21.918 1.00 32.30 ? 270 PHE B CZ 1 ATOM 1999 N N . HIS B 2 101 ? 18.405 -5.955 24.939 1.00 34.10 ? 271 HIS B N 1 ATOM 2000 C CA . HIS B 2 101 ? 17.185 -6.516 25.488 1.00 36.08 ? 271 HIS B CA 1 ATOM 2001 C C . HIS B 2 101 ? 16.336 -7.017 24.338 1.00 33.82 ? 271 HIS B C 1 ATOM 2002 O O . HIS B 2 101 ? 15.735 -6.236 23.580 1.00 32.97 ? 271 HIS B O 1 ATOM 2003 C CB . HIS B 2 101 ? 16.453 -5.489 26.362 1.00 39.87 ? 271 HIS B CB 1 ATOM 2004 C CG . HIS B 2 101 ? 15.334 -6.068 27.174 1.00 44.30 ? 271 HIS B CG 1 ATOM 2005 N ND1 . HIS B 2 101 ? 14.260 -5.315 27.605 1.00 46.57 ? 271 HIS B ND1 1 ATOM 2006 C CD2 . HIS B 2 101 ? 15.117 -7.325 27.630 1.00 46.10 ? 271 HIS B CD2 1 ATOM 2007 C CE1 . HIS B 2 101 ? 13.434 -6.082 28.295 1.00 46.98 ? 271 HIS B CE1 1 ATOM 2008 N NE2 . HIS B 2 101 ? 13.927 -7.308 28.318 1.00 47.15 ? 271 HIS B NE2 1 ATOM 2009 N N . LEU B 2 102 ? 16.321 -8.337 24.209 1.00 31.17 ? 272 LEU B N 1 ATOM 2010 C CA . LEU B 2 102 ? 15.704 -8.997 23.079 1.00 30.27 ? 272 LEU B CA 1 ATOM 2011 C C . LEU B 2 102 ? 14.846 -10.127 23.600 1.00 29.40 ? 272 LEU B C 1 ATOM 2012 O O . LEU B 2 102 ? 15.358 -11.063 24.235 1.00 27.95 ? 272 LEU B O 1 ATOM 2013 C CB . LEU B 2 102 ? 16.773 -9.553 22.125 1.00 28.70 ? 272 LEU B CB 1 ATOM 2014 C CG . LEU B 2 102 ? 17.784 -8.614 21.465 1.00 30.10 ? 272 LEU B CG 1 ATOM 2015 C CD1 . LEU B 2 102 ? 18.934 -9.418 20.831 1.00 28.87 ? 272 LEU B CD1 1 ATOM 2016 C CD2 . LEU B 2 102 ? 17.113 -7.700 20.428 1.00 30.56 ? 272 LEU B CD2 1 ATOM 2017 N N . GLY B 2 103 ? 13.547 -10.035 23.327 1.00 30.15 ? 273 GLY B N 1 ATOM 2018 C CA . GLY B 2 103 ? 12.577 -11.007 23.830 1.00 33.50 ? 273 GLY B CA 1 ATOM 2019 C C . GLY B 2 103 ? 12.481 -10.972 25.347 1.00 35.10 ? 273 GLY B C 1 ATOM 2020 O O . GLY B 2 103 ? 12.344 -9.909 25.944 1.00 36.63 ? 273 GLY B O 1 ATOM 2021 N N . GLY B 2 104 ? 12.554 -12.134 25.979 1.00 37.06 ? 274 GLY B N 1 ATOM 2022 C CA . GLY B 2 104 ? 12.475 -12.193 27.439 1.00 37.33 ? 274 GLY B CA 1 ATOM 2023 C C . GLY B 2 104 ? 13.811 -11.996 28.138 1.00 38.78 ? 274 GLY B C 1 ATOM 2024 O O . GLY B 2 104 ? 13.876 -12.017 29.370 1.00 41.11 ? 274 GLY B O 1 ATOM 2025 N N . LYS B 2 105 ? 14.868 -11.769 27.359 1.00 37.13 ? 275 LYS B N 1 ATOM 2026 C CA . LYS B 2 105 ? 16.237 -11.850 27.863 1.00 37.18 ? 275 LYS B CA 1 ATOM 2027 C C . LYS B 2 105 ? 17.134 -10.633 27.595 1.00 35.85 ? 275 LYS B C 1 ATOM 2028 O O . LYS B 2 105 ? 16.906 -9.857 26.656 1.00 33.77 ? 275 LYS B O 1 ATOM 2029 C CB . LYS B 2 105 ? 16.914 -13.093 27.276 1.00 39.00 ? 275 LYS B CB 1 ATOM 2030 C CG . LYS B 2 105 ? 16.812 -14.320 28.127 1.00 40.72 ? 275 LYS B CG 1 ATOM 2031 C CD . LYS B 2 105 ? 17.605 -15.469 27.545 1.00 43.36 ? 275 LYS B CD 1 ATOM 2032 C CE . LYS B 2 105 ? 19.077 -15.114 27.301 1.00 45.39 ? 275 LYS B CE 1 ATOM 2033 N NZ . LYS B 2 105 ? 19.795 -14.597 28.506 1.00 46.72 ? 275 LYS B NZ 1 ATOM 2034 N N . GLU B 2 106 ? 18.162 -10.497 28.434 1.00 34.78 ? 276 GLU B N 1 ATOM 2035 C CA . GLU B 2 106 ? 19.263 -9.572 28.191 1.00 35.34 ? 276 GLU B CA 1 ATOM 2036 C C . GLU B 2 106 ? 20.442 -10.328 27.587 1.00 33.14 ? 276 GLU B C 1 ATOM 2037 O O . GLU B 2 106 ? 20.870 -11.371 28.079 1.00 33.37 ? 276 GLU B O 1 ATOM 2038 C CB . GLU B 2 106 ? 19.689 -8.826 29.469 1.00 37.40 ? 276 GLU B CB 1 ATOM 2039 C CG . GLU B 2 106 ? 18.659 -7.800 29.999 1.00 40.45 ? 276 GLU B CG 1 ATOM 2040 C CD . GLU B 2 106 ? 18.703 -6.456 29.271 1.00 41.60 ? 276 GLU B CD 1 ATOM 2041 O OE1 . GLU B 2 106 ? 19.643 -6.230 28.477 1.00 43.65 ? 276 GLU B OE1 1 ATOM 2042 O OE2 . GLU B 2 106 ? 17.800 -5.618 29.494 1.00 41.20 ? 276 GLU B OE2 1 ATOM 2043 N N . TYR B 2 107 ? 20.949 -9.793 26.492 1.00 33.93 ? 277 TYR B N 1 ATOM 2044 C CA . TYR B 2 107 ? 22.119 -10.344 25.842 1.00 33.07 ? 277 TYR B CA 1 ATOM 2045 C C . TYR B 2 107 ? 23.302 -9.433 26.123 1.00 31.89 ? 277 TYR B C 1 ATOM 2046 O O . TYR B 2 107 ? 23.431 -8.331 25.573 1.00 32.28 ? 277 TYR B O 1 ATOM 2047 C CB . TYR B 2 107 ? 21.847 -10.541 24.358 1.00 32.87 ? 277 TYR B CB 1 ATOM 2048 C CG . TYR B 2 107 ? 20.833 -11.638 24.121 1.00 33.12 ? 277 TYR B CG 1 ATOM 2049 C CD1 . TYR B 2 107 ? 21.240 -12.952 23.896 1.00 32.75 ? 277 TYR B CD1 1 ATOM 2050 C CD2 . TYR B 2 107 ? 19.461 -11.365 24.140 1.00 33.35 ? 277 TYR B CD2 1 ATOM 2051 C CE1 . TYR B 2 107 ? 20.308 -13.966 23.685 1.00 32.98 ? 277 TYR B CE1 1 ATOM 2052 C CE2 . TYR B 2 107 ? 18.525 -12.366 23.928 1.00 32.25 ? 277 TYR B CE2 1 ATOM 2053 C CZ . TYR B 2 107 ? 18.954 -13.659 23.707 1.00 33.04 ? 277 TYR B CZ 1 ATOM 2054 O OH . TYR B 2 107 ? 18.029 -14.649 23.506 1.00 33.85 ? 277 TYR B OH 1 ATOM 2055 N N . THR B 2 108 ? 24.143 -9.915 27.023 1.00 31.27 ? 278 THR B N 1 ATOM 2056 C CA . THR B 2 108 ? 25.211 -9.132 27.614 1.00 32.12 ? 278 THR B CA 1 ATOM 2057 C C . THR B 2 108 ? 26.542 -9.428 26.945 1.00 30.94 ? 278 THR B C 1 ATOM 2058 O O . THR B 2 108 ? 27.006 -10.573 26.957 1.00 30.57 ? 278 THR B O 1 ATOM 2059 C CB . THR B 2 108 ? 25.308 -9.419 29.147 1.00 33.08 ? 278 THR B CB 1 ATOM 2060 O OG1 . THR B 2 108 ? 24.057 -9.084 29.765 1.00 34.40 ? 278 THR B OG1 1 ATOM 2061 C CG2 . THR B 2 108 ? 26.436 -8.607 29.811 1.00 32.37 ? 278 THR B CG2 1 ATOM 2062 N N . LEU B 2 109 ? 27.145 -8.382 26.380 1.00 31.53 ? 279 LEU B N 1 ATOM 2063 C CA . LEU B 2 109 ? 28.536 -8.417 25.937 1.00 33.06 ? 279 LEU B CA 1 ATOM 2064 C C . LEU B 2 109 ? 29.458 -7.717 26.928 1.00 31.78 ? 279 LEU B C 1 ATOM 2065 O O . LEU B 2 109 ? 29.274 -6.545 27.223 1.00 31.88 ? 279 LEU B O 1 ATOM 2066 C CB . LEU B 2 109 ? 28.694 -7.744 24.569 1.00 33.04 ? 279 LEU B CB 1 ATOM 2067 C CG . LEU B 2 109 ? 27.904 -8.230 23.365 1.00 32.90 ? 279 LEU B CG 1 ATOM 2068 C CD1 . LEU B 2 109 ? 28.483 -7.560 22.153 1.00 33.52 ? 279 LEU B CD1 1 ATOM 2069 C CD2 . LEU B 2 109 ? 27.948 -9.730 23.218 1.00 32.33 ? 279 LEU B CD2 1 ATOM 2070 N N . THR B 2 110 ? 30.467 -8.428 27.415 1.00 32.86 ? 280 THR B N 1 ATOM 2071 C CA . THR B 2 110 ? 31.505 -7.806 28.251 1.00 32.68 ? 280 THR B CA 1 ATOM 2072 C C . THR B 2 110 ? 32.534 -7.106 27.355 1.00 32.93 ? 280 THR B C 1 ATOM 2073 O O . THR B 2 110 ? 32.445 -7.179 26.130 1.00 31.15 ? 280 THR B O 1 ATOM 2074 C CB . THR B 2 110 ? 32.204 -8.829 29.172 1.00 33.04 ? 280 THR B CB 1 ATOM 2075 O OG1 . THR B 2 110 ? 32.996 -9.722 28.383 1.00 35.56 ? 280 THR B OG1 1 ATOM 2076 C CG2 . THR B 2 110 ? 31.178 -9.644 29.953 1.00 32.65 ? 280 THR B CG2 1 ATOM 2077 N N . SER B 2 111 ? 33.503 -6.429 27.971 1.00 34.45 ? 281 SER B N 1 ATOM 2078 C CA . SER B 2 111 ? 34.556 -5.717 27.239 1.00 34.14 ? 281 SER B CA 1 ATOM 2079 C C . SER B 2 111 ? 35.384 -6.642 26.347 1.00 31.97 ? 281 SER B C 1 ATOM 2080 O O . SER B 2 111 ? 35.814 -6.242 25.281 1.00 31.87 ? 281 SER B O 1 ATOM 2081 C CB . SER B 2 111 ? 35.482 -4.991 28.215 1.00 34.62 ? 281 SER B CB 1 ATOM 2082 O OG . SER B 2 111 ? 35.955 -5.902 29.190 1.00 37.12 ? 281 SER B OG 1 ATOM 2083 N N . ALA B 2 112 ? 35.614 -7.868 26.797 1.00 30.96 ? 282 ALA B N 1 ATOM 2084 C CA . ALA B 2 112 ? 36.345 -8.846 26.009 1.00 32.36 ? 282 ALA B CA 1 ATOM 2085 C C . ALA B 2 112 ? 35.592 -9.215 24.728 1.00 33.48 ? 282 ALA B C 1 ATOM 2086 O O . ALA B 2 112 ? 36.187 -9.737 23.783 1.00 33.99 ? 282 ALA B O 1 ATOM 2087 C CB . ALA B 2 112 ? 36.615 -10.091 26.844 1.00 32.99 ? 282 ALA B CB 1 ATOM 2088 N N . ASP B 2 113 ? 34.283 -8.946 24.713 1.00 32.58 ? 283 ASP B N 1 ATOM 2089 C CA . ASP B 2 113 ? 33.435 -9.247 23.568 1.00 31.23 ? 283 ASP B CA 1 ATOM 2090 C C . ASP B 2 113 ? 33.431 -8.129 22.513 1.00 30.40 ? 283 ASP B C 1 ATOM 2091 O O . ASP B 2 113 ? 33.109 -8.384 21.345 1.00 29.85 ? 283 ASP B O 1 ATOM 2092 C CB . ASP B 2 113 ? 32.005 -9.586 24.015 1.00 31.32 ? 283 ASP B CB 1 ATOM 2093 C CG . ASP B 2 113 ? 31.953 -10.753 25.010 1.00 33.11 ? 283 ASP B CG 1 ATOM 2094 O OD1 . ASP B 2 113 ? 32.546 -11.814 24.733 1.00 33.07 ? 283 ASP B OD1 1 ATOM 2095 O OD2 . ASP B 2 113 ? 31.307 -10.613 26.076 1.00 33.00 ? 283 ASP B OD2 1 ATOM 2096 N N . TYR B 2 114 ? 33.803 -6.905 22.899 1.00 28.26 ? 284 TYR B N 1 ATOM 2097 C CA . TYR B 2 114 ? 33.739 -5.781 21.948 1.00 27.23 ? 284 TYR B CA 1 ATOM 2098 C C . TYR B 2 114 ? 34.960 -4.876 21.854 1.00 28.24 ? 284 TYR B C 1 ATOM 2099 O O . TYR B 2 114 ? 34.972 -3.943 21.038 1.00 29.00 ? 284 TYR B O 1 ATOM 2100 C CB . TYR B 2 114 ? 32.457 -4.951 22.127 1.00 27.68 ? 284 TYR B CB 1 ATOM 2101 C CG . TYR B 2 114 ? 32.368 -4.195 23.425 1.00 27.07 ? 284 TYR B CG 1 ATOM 2102 C CD1 . TYR B 2 114 ? 32.867 -2.889 23.524 1.00 27.08 ? 284 TYR B CD1 1 ATOM 2103 C CD2 . TYR B 2 114 ? 31.787 -4.774 24.551 1.00 24.13 ? 284 TYR B CD2 1 ATOM 2104 C CE1 . TYR B 2 114 ? 32.813 -2.177 24.718 1.00 26.35 ? 284 TYR B CE1 1 ATOM 2105 C CE2 . TYR B 2 114 ? 31.712 -4.071 25.749 1.00 27.30 ? 284 TYR B CE2 1 ATOM 2106 C CZ . TYR B 2 114 ? 32.234 -2.771 25.824 1.00 27.54 ? 284 TYR B CZ 1 ATOM 2107 O OH . TYR B 2 114 ? 32.153 -2.058 26.994 1.00 28.11 ? 284 TYR B OH 1 ATOM 2108 N N . VAL B 2 115 ? 35.984 -5.138 22.660 1.00 26.80 ? 285 VAL B N 1 ATOM 2109 C CA . VAL B 2 115 ? 37.228 -4.369 22.569 1.00 27.99 ? 285 VAL B CA 1 ATOM 2110 C C . VAL B 2 115 ? 38.310 -5.185 21.867 1.00 28.28 ? 285 VAL B C 1 ATOM 2111 O O . VAL B 2 115 ? 38.638 -6.301 22.313 1.00 28.29 ? 285 VAL B O 1 ATOM 2112 C CB . VAL B 2 115 ? 37.740 -3.924 23.984 1.00 28.60 ? 285 VAL B CB 1 ATOM 2113 C CG1 . VAL B 2 115 ? 39.145 -3.330 23.906 1.00 25.73 ? 285 VAL B CG1 1 ATOM 2114 C CG2 . VAL B 2 115 ? 36.774 -2.924 24.603 1.00 29.37 ? 285 VAL B CG2 1 ATOM 2115 N N . PHE B 2 116 ? 38.858 -4.642 20.783 1.00 26.30 ? 286 PHE B N 1 ATOM 2116 C CA . PHE B 2 116 ? 40.016 -5.268 20.145 1.00 29.00 ? 286 PHE B CA 1 ATOM 2117 C C . PHE B 2 116 ? 41.238 -4.960 21.006 1.00 29.26 ? 286 PHE B C 1 ATOM 2118 O O . PHE B 2 116 ? 41.898 -3.934 20.839 1.00 29.40 ? 286 PHE B O 1 ATOM 2119 C CB . PHE B 2 116 ? 40.216 -4.813 18.683 1.00 30.13 ? 286 PHE B CB 1 ATOM 2120 C CG . PHE B 2 116 ? 39.210 -5.393 17.707 1.00 30.64 ? 286 PHE B CG 1 ATOM 2121 C CD1 . PHE B 2 116 ? 39.379 -6.669 17.183 1.00 31.97 ? 286 PHE B CD1 1 ATOM 2122 C CD2 . PHE B 2 116 ? 38.099 -4.645 17.303 1.00 31.77 ? 286 PHE B CD2 1 ATOM 2123 C CE1 . PHE B 2 116 ? 38.439 -7.211 16.279 1.00 33.78 ? 286 PHE B CE1 1 ATOM 2124 C CE2 . PHE B 2 116 ? 37.152 -5.165 16.403 1.00 32.76 ? 286 PHE B CE2 1 ATOM 2125 C CZ . PHE B 2 116 ? 37.320 -6.455 15.889 1.00 32.57 ? 286 PHE B CZ 1 ATOM 2126 N N . GLN B 2 117 ? 41.510 -5.859 21.943 1.00 29.52 ? 287 GLN B N 1 ATOM 2127 C CA . GLN B 2 117 ? 42.610 -5.723 22.872 1.00 30.79 ? 287 GLN B CA 1 ATOM 2128 C C . GLN B 2 117 ? 43.943 -6.113 22.225 1.00 30.17 ? 287 GLN B C 1 ATOM 2129 O O . GLN B 2 117 ? 44.481 -7.176 22.483 1.00 30.97 ? 287 GLN B O 1 ATOM 2130 C CB . GLN B 2 117 ? 42.343 -6.579 24.118 1.00 31.17 ? 287 GLN B CB 1 ATOM 2131 C CG . GLN B 2 117 ? 43.048 -6.060 25.353 1.00 32.40 ? 287 GLN B CG 1 ATOM 2132 C CD . GLN B 2 117 ? 42.488 -4.727 25.818 1.00 33.00 ? 287 GLN B CD 1 ATOM 2133 O OE1 . GLN B 2 117 ? 41.279 -4.563 25.922 1.00 34.13 ? 287 GLN B OE1 1 ATOM 2134 N NE2 . GLN B 2 117 ? 43.362 -3.775 26.097 1.00 32.46 ? 287 GLN B NE2 1 ATOM 2135 N N . GLU B 2 118 ? 44.469 -5.237 21.391 1.00 32.35 ? 288 GLU B N 1 ATOM 2136 C CA . GLU B 2 118 ? 45.710 -5.496 20.672 1.00 36.65 ? 288 GLU B CA 1 ATOM 2137 C C . GLU B 2 118 ? 46.939 -5.113 21.506 1.00 37.37 ? 288 GLU B C 1 ATOM 2138 O O . GLU B 2 118 ? 48.076 -5.417 21.133 1.00 37.92 ? 288 GLU B O 1 ATOM 2139 C CB . GLU B 2 118 ? 45.693 -4.753 19.337 1.00 36.61 ? 288 GLU B CB 1 ATOM 2140 C CG . GLU B 2 118 ? 44.911 -5.499 18.254 1.00 40.74 ? 288 GLU B CG 1 ATOM 2141 C CD . GLU B 2 118 ? 44.716 -4.677 16.989 1.00 42.47 ? 288 GLU B CD 1 ATOM 2142 O OE1 . GLU B 2 118 ? 45.239 -5.085 15.932 1.00 45.12 ? 288 GLU B OE1 1 ATOM 2143 O OE2 . GLU B 2 118 ? 44.050 -3.620 17.053 1.00 45.44 ? 288 GLU B OE2 1 ATOM 2144 N N . SER B 2 119 ? 46.688 -4.462 22.639 1.00 37.32 ? 289 SER B N 1 ATOM 2145 C CA . SER B 2 119 ? 47.718 -4.028 23.566 1.00 39.21 ? 289 SER B CA 1 ATOM 2146 C C . SER B 2 119 ? 47.027 -3.727 24.893 1.00 41.08 ? 289 SER B C 1 ATOM 2147 O O . SER B 2 119 ? 45.806 -3.548 24.922 1.00 39.94 ? 289 SER B O 1 ATOM 2148 C CB . SER B 2 119 ? 48.398 -2.773 23.013 1.00 39.14 ? 289 SER B CB 1 ATOM 2149 O OG . SER B 2 119 ? 49.237 -2.159 23.962 1.00 38.95 ? 289 SER B OG 1 ATOM 2150 N N . TYR B 2 120 ? 47.796 -3.684 25.985 1.00 42.38 ? 290 TYR B N 1 ATOM 2151 C CA . TYR B 2 120 ? 47.279 -3.191 27.275 1.00 42.41 ? 290 TYR B CA 1 ATOM 2152 C C . TYR B 2 120 ? 47.957 -1.889 27.704 1.00 44.16 ? 290 TYR B C 1 ATOM 2153 O O . TYR B 2 120 ? 47.976 -1.554 28.889 1.00 46.76 ? 290 TYR B O 1 ATOM 2154 C CB . TYR B 2 120 ? 47.402 -4.254 28.368 1.00 39.89 ? 290 TYR B CB 1 ATOM 2155 C CG . TYR B 2 120 ? 46.548 -5.472 28.117 1.00 39.87 ? 290 TYR B CG 1 ATOM 2156 C CD1 . TYR B 2 120 ? 45.230 -5.536 28.575 1.00 39.90 ? 290 TYR B CD1 1 ATOM 2157 C CD2 . TYR B 2 120 ? 47.047 -6.553 27.398 1.00 39.18 ? 290 TYR B CD2 1 ATOM 2158 C CE1 . TYR B 2 120 ? 44.441 -6.659 28.335 1.00 38.12 ? 290 TYR B CE1 1 ATOM 2159 C CE2 . TYR B 2 120 ? 46.266 -7.665 27.151 1.00 38.38 ? 290 TYR B CE2 1 ATOM 2160 C CZ . TYR B 2 120 ? 44.972 -7.716 27.623 1.00 38.24 ? 290 TYR B CZ 1 ATOM 2161 O OH . TYR B 2 120 ? 44.215 -8.832 27.360 1.00 38.93 ? 290 TYR B OH 1 ATOM 2162 N N . SER B 2 121 ? 48.482 -1.151 26.729 1.00 44.87 ? 291 SER B N 1 ATOM 2163 C CA . SER B 2 121 ? 49.301 0.031 26.989 1.00 47.11 ? 291 SER B CA 1 ATOM 2164 C C . SER B 2 121 ? 48.541 1.350 26.859 1.00 48.41 ? 291 SER B C 1 ATOM 2165 O O . SER B 2 121 ? 47.722 1.530 25.948 1.00 47.61 ? 291 SER B O 1 ATOM 2166 C CB . SER B 2 121 ? 50.517 0.038 26.058 1.00 46.76 ? 291 SER B CB 1 ATOM 2167 O OG . SER B 2 121 ? 51.146 1.306 26.045 1.00 47.75 ? 291 SER B OG 1 ATOM 2168 N N . SER B 2 122 ? 48.843 2.280 27.763 1.00 50.41 ? 292 SER B N 1 ATOM 2169 C CA . SER B 2 122 ? 48.197 3.596 27.780 1.00 51.28 ? 292 SER B CA 1 ATOM 2170 C C . SER B 2 122 ? 48.702 4.506 26.658 1.00 53.38 ? 292 SER B C 1 ATOM 2171 O O . SER B 2 122 ? 48.070 5.516 26.334 1.00 52.71 ? 292 SER B O 1 ATOM 2172 C CB . SER B 2 122 ? 48.351 4.258 29.148 1.00 51.59 ? 292 SER B CB 1 ATOM 2173 O OG . SER B 2 122 ? 49.554 3.855 29.778 1.00 52.34 ? 292 SER B OG 1 ATOM 2174 N N . LYS B 2 123 ? 49.824 4.125 26.050 1.00 55.64 ? 293 LYS B N 1 ATOM 2175 C CA . LYS B 2 123 ? 50.376 4.855 24.911 1.00 57.32 ? 293 LYS B CA 1 ATOM 2176 C C . LYS B 2 123 ? 49.734 4.402 23.598 1.00 57.57 ? 293 LYS B C 1 ATOM 2177 O O . LYS B 2 123 ? 49.961 5.008 22.541 1.00 57.13 ? 293 LYS B O 1 ATOM 2178 C CB . LYS B 2 123 ? 51.902 4.695 24.847 1.00 59.53 ? 293 LYS B CB 1 ATOM 2179 C CG . LYS B 2 123 ? 52.663 5.190 26.088 1.00 61.46 ? 293 LYS B CG 1 ATOM 2180 C CD . LYS B 2 123 ? 52.947 4.046 27.077 1.00 63.01 ? 293 LYS B CD 1 ATOM 2181 C CE . LYS B 2 123 ? 53.390 4.559 28.446 1.00 63.95 ? 293 LYS B CE 1 ATOM 2182 N NZ . LYS B 2 123 ? 54.576 5.465 28.370 1.00 64.32 ? 293 LYS B NZ 1 ATOM 2183 N N . LYS B 2 124 ? 48.921 3.346 23.678 1.00 56.93 ? 294 LYS B N 1 ATOM 2184 C CA . LYS B 2 124 ? 48.296 2.734 22.498 1.00 55.44 ? 294 LYS B CA 1 ATOM 2185 C C . LYS B 2 124 ? 46.773 2.860 22.499 1.00 53.19 ? 294 LYS B C 1 ATOM 2186 O O . LYS B 2 124 ? 46.145 2.856 23.562 1.00 53.75 ? 294 LYS B O 1 ATOM 2187 C CB . LYS B 2 124 ? 48.691 1.255 22.406 1.00 57.05 ? 294 LYS B CB 1 ATOM 2188 C CG . LYS B 2 124 ? 50.179 1.004 22.156 1.00 58.19 ? 294 LYS B CG 1 ATOM 2189 C CD . LYS B 2 124 ? 50.468 0.876 20.673 1.00 59.86 ? 294 LYS B CD 1 ATOM 2190 C CE . LYS B 2 124 ? 51.962 0.804 20.399 1.00 62.31 ? 294 LYS B CE 1 ATOM 2191 N NZ . LYS B 2 124 ? 52.626 2.143 20.477 1.00 63.15 ? 294 LYS B NZ 1 ATOM 2192 N N . LEU B 2 125 ? 46.193 2.961 21.302 1.00 50.04 ? 295 LEU B N 1 ATOM 2193 C CA . LEU B 2 125 ? 44.737 3.015 21.126 1.00 47.80 ? 295 LEU B CA 1 ATOM 2194 C C . LEU B 2 125 ? 44.143 1.694 20.627 1.00 46.47 ? 295 LEU B C 1 ATOM 2195 O O . LEU B 2 125 ? 44.604 1.119 19.638 1.00 47.31 ? 295 LEU B O 1 ATOM 2196 C CB . LEU B 2 125 ? 44.339 4.150 20.175 1.00 47.21 ? 295 LEU B CB 1 ATOM 2197 C CG . LEU B 2 125 ? 44.675 5.580 20.608 1.00 47.85 ? 295 LEU B CG 1 ATOM 2198 C CD1 . LEU B 2 125 ? 44.570 6.547 19.433 1.00 47.12 ? 295 LEU B CD1 1 ATOM 2199 C CD2 . LEU B 2 125 ? 43.804 6.032 21.779 1.00 46.69 ? 295 LEU B CD2 1 ATOM 2200 N N . CYS B 2 126 ? 43.108 1.231 21.321 1.00 44.31 ? 296 CYS B N 1 ATOM 2201 C CA . CYS B 2 126 ? 42.397 0.007 20.969 1.00 41.08 ? 296 CYS B CA 1 ATOM 2202 C C . CYS B 2 126 ? 41.004 0.304 20.391 1.00 39.86 ? 296 CYS B C 1 ATOM 2203 O O . CYS B 2 126 ? 40.256 1.130 20.917 1.00 37.82 ? 296 CYS B O 1 ATOM 2204 C CB . CYS B 2 126 ? 42.300 -0.902 22.190 1.00 40.15 ? 296 CYS B CB 1 ATOM 2205 S SG . CYS B 2 126 ? 43.828 -1.786 22.582 1.00 42.84 ? 296 CYS B SG 1 ATOM 2206 N N . THR B 2 127 ? 40.669 -0.384 19.306 1.00 40.45 ? 297 THR B N 1 ATOM 2207 C CA . THR B 2 127 ? 39.404 -0.195 18.593 1.00 40.13 ? 297 THR B CA 1 ATOM 2208 C C . THR B 2 127 ? 38.247 -0.926 19.265 1.00 38.16 ? 297 THR B C 1 ATOM 2209 O O . THR B 2 127 ? 38.444 -1.913 19.971 1.00 38.63 ? 297 THR B O 1 ATOM 2210 C CB . THR B 2 127 ? 39.510 -0.710 17.142 1.00 42.41 ? 297 THR B CB 1 ATOM 2211 O OG1 . THR B 2 127 ? 40.865 -0.618 16.691 1.00 45.23 ? 297 THR B OG1 1 ATOM 2212 C CG2 . THR B 2 127 ? 38.631 0.103 16.220 1.00 43.12 ? 297 THR B CG2 1 ATOM 2213 N N . LEU B 2 128 ? 37.037 -0.438 19.019 1.00 36.82 ? 298 LEU B N 1 ATOM 2214 C CA . LEU B 2 128 ? 35.816 -1.073 19.509 1.00 33.77 ? 298 LEU B CA 1 ATOM 2215 C C . LEU B 2 128 ? 35.077 -1.756 18.362 1.00 32.42 ? 298 LEU B C 1 ATOM 2216 O O . LEU B 2 128 ? 35.008 -1.217 17.249 1.00 32.28 ? 298 LEU B O 1 ATOM 2217 C CB . LEU B 2 128 ? 34.916 -0.041 20.195 1.00 33.15 ? 298 LEU B CB 1 ATOM 2218 C CG . LEU B 2 128 ? 35.593 0.850 21.251 1.00 33.78 ? 298 LEU B CG 1 ATOM 2219 C CD1 . LEU B 2 128 ? 34.607 1.795 21.863 1.00 32.67 ? 298 LEU B CD1 1 ATOM 2220 C CD2 . LEU B 2 128 ? 36.282 0.032 22.341 1.00 34.46 ? 298 LEU B CD2 1 ATOM 2221 N N . ALA B 2 129 ? 34.530 -2.940 18.637 1.00 31.48 ? 299 ALA B N 1 ATOM 2222 C CA . ALA B 2 129 ? 33.813 -3.731 17.628 1.00 32.92 ? 299 ALA B CA 1 ATOM 2223 C C . ALA B 2 129 ? 32.356 -3.256 17.468 1.00 34.71 ? 299 ALA B C 1 ATOM 2224 O O . ALA B 2 129 ? 31.435 -4.058 17.253 1.00 33.26 ? 299 ALA B O 1 ATOM 2225 C CB . ALA B 2 129 ? 33.883 -5.211 17.968 1.00 31.85 ? 299 ALA B CB 1 ATOM 2226 N N . ILE B 2 130 ? 32.179 -1.937 17.586 1.00 35.52 ? 300 ILE B N 1 ATOM 2227 C CA . ILE B 2 130 ? 30.897 -1.257 17.442 1.00 35.03 ? 300 ILE B CA 1 ATOM 2228 C C . ILE B 2 130 ? 31.119 0.008 16.600 1.00 36.24 ? 300 ILE B C 1 ATOM 2229 O O . ILE B 2 130 ? 32.006 0.803 16.895 1.00 37.02 ? 300 ILE B O 1 ATOM 2230 C CB . ILE B 2 130 ? 30.322 -0.883 18.823 1.00 34.54 ? 300 ILE B CB 1 ATOM 2231 C CG1 . ILE B 2 130 ? 30.103 -2.144 19.677 1.00 32.86 ? 300 ILE B CG1 1 ATOM 2232 C CG2 . ILE B 2 130 ? 29.028 -0.057 18.682 1.00 33.87 ? 300 ILE B CG2 1 ATOM 2233 C CD1 . ILE B 2 130 ? 29.962 -1.864 21.150 1.00 31.94 ? 300 ILE B CD1 1 ATOM 2234 N N A HIS B 2 131 ? 30.311 0.179 15.559 0.50 36.17 ? 301 HIS B N 1 ATOM 2235 N N B HIS B 2 131 ? 30.336 0.173 15.539 0.50 36.51 ? 301 HIS B N 1 ATOM 2236 C CA A HIS B 2 131 ? 30.440 1.312 14.645 0.50 36.43 ? 301 HIS B CA 1 ATOM 2237 C CA B HIS B 2 131 ? 30.461 1.353 14.686 0.50 37.01 ? 301 HIS B CA 1 ATOM 2238 C C A HIS B 2 131 ? 29.082 1.973 14.409 0.50 37.79 ? 301 HIS B C 1 ATOM 2239 C C B HIS B 2 131 ? 29.100 1.935 14.306 0.50 38.13 ? 301 HIS B C 1 ATOM 2240 O O A HIS B 2 131 ? 28.039 1.390 14.719 0.50 36.99 ? 301 HIS B O 1 ATOM 2241 O O B HIS B 2 131 ? 28.074 1.266 14.432 0.50 37.45 ? 301 HIS B O 1 ATOM 2242 C CB A HIS B 2 131 ? 31.033 0.850 13.311 0.50 35.27 ? 301 HIS B CB 1 ATOM 2243 C CB B HIS B 2 131 ? 31.339 1.058 13.456 0.50 36.45 ? 301 HIS B CB 1 ATOM 2244 C CG A HIS B 2 131 ? 32.465 0.411 13.397 0.50 35.02 ? 301 HIS B CG 1 ATOM 2245 C CG B HIS B 2 131 ? 30.606 0.458 12.294 0.50 36.31 ? 301 HIS B CG 1 ATOM 2246 N ND1 A HIS B 2 131 ? 33.467 0.999 12.655 0.50 34.58 ? 301 HIS B ND1 1 ATOM 2247 N ND1 B HIS B 2 131 ? 29.828 -0.676 12.399 0.50 35.53 ? 301 HIS B ND1 1 ATOM 2248 C CD2 A HIS B 2 131 ? 33.062 -0.558 14.131 0.50 34.30 ? 301 HIS B CD2 1 ATOM 2249 C CD2 B HIS B 2 131 ? 30.563 0.822 10.989 0.50 36.18 ? 301 HIS B CD2 1 ATOM 2250 C CE1 A HIS B 2 131 ? 34.617 0.410 12.927 0.50 33.59 ? 301 HIS B CE1 1 ATOM 2251 C CE1 B HIS B 2 131 ? 29.323 -0.971 11.215 0.50 35.19 ? 301 HIS B CE1 1 ATOM 2252 N NE2 A HIS B 2 131 ? 34.399 -0.539 13.819 0.50 33.70 ? 301 HIS B NE2 1 ATOM 2253 N NE2 B HIS B 2 131 ? 29.754 -0.078 10.342 0.50 35.03 ? 301 HIS B NE2 1 ATOM 2254 N N . ALA B 2 132 ? 29.102 3.193 13.874 1.00 39.21 ? 302 ALA B N 1 ATOM 2255 C CA . ALA B 2 132 ? 27.876 3.886 13.487 1.00 41.23 ? 302 ALA B CA 1 ATOM 2256 C C . ALA B 2 132 ? 27.616 3.663 12.008 1.00 44.54 ? 302 ALA B C 1 ATOM 2257 O O . ALA B 2 132 ? 28.500 3.878 11.166 1.00 43.62 ? 302 ALA B O 1 ATOM 2258 C CB . ALA B 2 132 ? 27.969 5.380 13.789 1.00 41.46 ? 302 ALA B CB 1 ATOM 2259 N N . MET B 2 133 ? 26.403 3.208 11.708 1.00 47.29 ? 303 MET B N 1 ATOM 2260 C CA . MET B 2 133 ? 25.921 3.104 10.345 1.00 50.66 ? 303 MET B CA 1 ATOM 2261 C C . MET B 2 133 ? 24.442 3.466 10.277 1.00 49.77 ? 303 MET B C 1 ATOM 2262 O O . MET B 2 133 ? 23.607 2.836 10.938 1.00 48.33 ? 303 MET B O 1 ATOM 2263 C CB . MET B 2 133 ? 26.142 1.701 9.793 1.00 51.76 ? 303 MET B CB 1 ATOM 2264 C CG . MET B 2 133 ? 25.463 1.470 8.450 1.00 54.58 ? 303 MET B CG 1 ATOM 2265 S SD . MET B 2 133 ? 25.901 -0.111 7.708 1.00 57.30 ? 303 MET B SD 1 ATOM 2266 C CE . MET B 2 133 ? 27.577 0.245 7.158 1.00 58.11 ? 303 MET B CE 1 ATOM 2267 N N . ASP B 2 134 ? 24.135 4.482 9.474 1.00 49.45 ? 304 ASP B N 1 ATOM 2268 C CA . ASP B 2 134 ? 22.758 4.874 9.207 1.00 49.96 ? 304 ASP B CA 1 ATOM 2269 C C . ASP B 2 134 ? 22.187 4.029 8.069 1.00 49.75 ? 304 ASP B C 1 ATOM 2270 O O . ASP B 2 134 ? 22.521 4.226 6.901 1.00 47.56 ? 304 ASP B O 1 ATOM 2271 C CB . ASP B 2 134 ? 22.675 6.367 8.877 1.00 51.45 ? 304 ASP B CB 1 ATOM 2272 C CG . ASP B 2 134 ? 23.206 7.239 9.999 1.00 52.86 ? 304 ASP B CG 1 ATOM 2273 O OD1 . ASP B 2 134 ? 22.697 7.123 11.135 1.00 51.78 ? 304 ASP B OD1 1 ATOM 2274 O OD2 . ASP B 2 134 ? 24.140 8.036 9.742 1.00 54.24 ? 304 ASP B OD2 1 ATOM 2275 N N . ILE B 2 135 ? 21.347 3.060 8.429 1.00 50.25 ? 305 ILE B N 1 ATOM 2276 C CA . ILE B 2 135 ? 20.714 2.208 7.435 1.00 50.88 ? 305 ILE B CA 1 ATOM 2277 C C . ILE B 2 135 ? 19.408 2.870 7.002 1.00 52.89 ? 305 ILE B C 1 ATOM 2278 O O . ILE B 2 135 ? 18.533 3.120 7.833 1.00 52.18 ? 305 ILE B O 1 ATOM 2279 C CB . ILE B 2 135 ? 20.516 0.753 7.943 1.00 50.10 ? 305 ILE B CB 1 ATOM 2280 C CG1 . ILE B 2 135 ? 21.881 0.105 8.217 1.00 49.14 ? 305 ILE B CG1 1 ATOM 2281 C CG2 . ILE B 2 135 ? 19.718 -0.081 6.929 1.00 48.97 ? 305 ILE B CG2 1 ATOM 2282 C CD1 . ILE B 2 135 ? 21.863 -1.012 9.252 1.00 48.25 ? 305 ILE B CD1 1 ATOM 2283 N N . PRO B 2 136 ? 19.295 3.186 5.699 1.00 54.67 ? 306 PRO B N 1 ATOM 2284 C CA . PRO B 2 136 ? 18.154 3.905 5.145 1.00 56.29 ? 306 PRO B CA 1 ATOM 2285 C C . PRO B 2 136 ? 16.891 3.042 5.059 1.00 58.09 ? 306 PRO B C 1 ATOM 2286 O O . PRO B 2 136 ? 17.001 1.814 4.953 1.00 58.24 ? 306 PRO B O 1 ATOM 2287 C CB . PRO B 2 136 ? 18.639 4.279 3.743 1.00 56.59 ? 306 PRO B CB 1 ATOM 2288 C CG . PRO B 2 136 ? 19.590 3.187 3.385 1.00 55.98 ? 306 PRO B CG 1 ATOM 2289 C CD . PRO B 2 136 ? 20.296 2.866 4.661 1.00 54.98 ? 306 PRO B CD 1 ATOM 2290 N N . PRO B 2 137 ? 15.697 3.677 5.117 1.00 59.25 ? 307 PRO B N 1 ATOM 2291 C CA . PRO B 2 137 ? 14.423 2.986 4.876 1.00 60.18 ? 307 PRO B CA 1 ATOM 2292 C C . PRO B 2 137 ? 14.431 2.198 3.561 1.00 61.75 ? 307 PRO B C 1 ATOM 2293 O O . PRO B 2 137 ? 15.106 2.611 2.611 1.00 61.05 ? 307 PRO B O 1 ATOM 2294 C CB . PRO B 2 137 ? 13.412 4.134 4.817 1.00 60.43 ? 307 PRO B CB 1 ATOM 2295 C CG . PRO B 2 137 ? 14.010 5.187 5.703 1.00 60.36 ? 307 PRO B CG 1 ATOM 2296 C CD . PRO B 2 137 ? 15.490 5.102 5.446 1.00 59.46 ? 307 PRO B CD 1 ATOM 2297 N N . PRO B 2 138 ? 13.688 1.068 3.500 1.00 63.16 ? 308 PRO B N 1 ATOM 2298 C CA . PRO B 2 138 ? 12.720 0.577 4.492 1.00 63.04 ? 308 PRO B CA 1 ATOM 2299 C C . PRO B 2 138 ? 13.330 -0.137 5.704 1.00 62.53 ? 308 PRO B C 1 ATOM 2300 O O . PRO B 2 138 ? 12.774 -0.045 6.802 1.00 62.47 ? 308 PRO B O 1 ATOM 2301 C CB . PRO B 2 138 ? 11.863 -0.401 3.685 1.00 63.60 ? 308 PRO B CB 1 ATOM 2302 C CG . PRO B 2 138 ? 12.783 -0.930 2.634 1.00 63.54 ? 308 PRO B CG 1 ATOM 2303 C CD . PRO B 2 138 ? 13.811 0.144 2.353 1.00 63.65 ? 308 PRO B CD 1 ATOM 2304 N N . THR B 2 139 ? 14.453 -0.830 5.509 1.00 61.23 ? 309 THR B N 1 ATOM 2305 C CA . THR B 2 139 ? 15.067 -1.619 6.580 1.00 60.03 ? 309 THR B CA 1 ATOM 2306 C C . THR B 2 139 ? 15.282 -0.792 7.851 1.00 58.50 ? 309 THR B C 1 ATOM 2307 O O . THR B 2 139 ? 14.820 -1.176 8.928 1.00 59.24 ? 309 THR B O 1 ATOM 2308 C CB . THR B 2 139 ? 16.404 -2.251 6.149 1.00 60.08 ? 309 THR B CB 1 ATOM 2309 O OG1 . THR B 2 139 ? 16.240 -2.920 4.894 1.00 61.10 ? 309 THR B OG1 1 ATOM 2310 C CG2 . THR B 2 139 ? 16.873 -3.247 7.187 1.00 59.87 ? 309 THR B CG2 1 ATOM 2311 N N . GLY B 2 140 ? 15.964 0.343 7.705 1.00 55.32 ? 310 GLY B N 1 ATOM 2312 C CA . GLY B 2 140 ? 16.287 1.205 8.832 1.00 53.14 ? 310 GLY B CA 1 ATOM 2313 C C . GLY B 2 140 ? 15.529 2.524 8.833 1.00 51.37 ? 310 GLY B C 1 ATOM 2314 O O . GLY B 2 140 ? 14.624 2.714 8.015 1.00 51.71 ? 310 GLY B O 1 ATOM 2315 N N . PRO B 2 141 ? 15.876 3.442 9.762 1.00 48.35 ? 311 PRO B N 1 ATOM 2316 C CA . PRO B 2 141 ? 16.854 3.312 10.858 1.00 47.66 ? 311 PRO B CA 1 ATOM 2317 C C . PRO B 2 141 ? 16.709 2.043 11.718 1.00 44.92 ? 311 PRO B C 1 ATOM 2318 O O . PRO B 2 141 ? 15.594 1.648 12.072 1.00 44.75 ? 311 PRO B O 1 ATOM 2319 C CB . PRO B 2 141 ? 16.604 4.569 11.719 1.00 48.58 ? 311 PRO B CB 1 ATOM 2320 C CG . PRO B 2 141 ? 15.331 5.189 11.179 1.00 48.72 ? 311 PRO B CG 1 ATOM 2321 C CD . PRO B 2 141 ? 15.273 4.784 9.743 1.00 48.08 ? 311 PRO B CD 1 ATOM 2322 N N . THR B 2 142 ? 17.846 1.421 12.032 1.00 41.64 ? 312 THR B N 1 ATOM 2323 C CA . THR B 2 142 ? 17.895 0.188 12.821 1.00 38.01 ? 312 THR B CA 1 ATOM 2324 C C . THR B 2 142 ? 19.292 -0.026 13.404 1.00 36.35 ? 312 THR B C 1 ATOM 2325 O O . THR B 2 142 ? 20.276 0.504 12.878 1.00 36.33 ? 312 THR B O 1 ATOM 2326 C CB . THR B 2 142 ? 17.482 -1.057 11.966 1.00 37.54 ? 312 THR B CB 1 ATOM 2327 O OG1 . THR B 2 142 ? 17.494 -2.238 12.772 1.00 37.30 ? 312 THR B OG1 1 ATOM 2328 C CG2 . THR B 2 142 ? 18.413 -1.259 10.769 1.00 37.12 ? 312 THR B CG2 1 ATOM 2329 N N . TRP B 2 143 ? 19.367 -0.772 14.505 1.00 34.52 ? 313 TRP B N 1 ATOM 2330 C CA . TRP B 2 143 ? 20.611 -1.411 14.924 1.00 34.03 ? 313 TRP B CA 1 ATOM 2331 C C . TRP B 2 143 ? 20.851 -2.638 14.044 1.00 33.21 ? 313 TRP B C 1 ATOM 2332 O O . TRP B 2 143 ? 19.915 -3.228 13.498 1.00 33.26 ? 313 TRP B O 1 ATOM 2333 C CB . TRP B 2 143 ? 20.547 -1.870 16.385 1.00 35.84 ? 313 TRP B CB 1 ATOM 2334 C CG . TRP B 2 143 ? 20.457 -0.759 17.400 1.00 37.24 ? 313 TRP B CG 1 ATOM 2335 C CD1 . TRP B 2 143 ? 19.341 -0.034 17.723 1.00 37.58 ? 313 TRP B CD1 1 ATOM 2336 C CD2 . TRP B 2 143 ? 21.510 -0.269 18.246 1.00 36.85 ? 313 TRP B CD2 1 ATOM 2337 N NE1 . TRP B 2 143 ? 19.634 0.876 18.705 1.00 37.75 ? 313 TRP B NE1 1 ATOM 2338 C CE2 . TRP B 2 143 ? 20.959 0.760 19.042 1.00 37.08 ? 313 TRP B CE2 1 ATOM 2339 C CE3 . TRP B 2 143 ? 22.865 -0.601 18.409 1.00 37.09 ? 313 TRP B CE3 1 ATOM 2340 C CZ2 . TRP B 2 143 ? 21.711 1.464 19.984 1.00 35.97 ? 313 TRP B CZ2 1 ATOM 2341 C CZ3 . TRP B 2 143 ? 23.614 0.093 19.346 1.00 37.02 ? 313 TRP B CZ3 1 ATOM 2342 C CH2 . TRP B 2 143 ? 23.032 1.122 20.122 1.00 37.34 ? 313 TRP B CH2 1 ATOM 2343 N N . ALA B 2 144 ? 22.113 -3.021 13.911 1.00 31.98 ? 314 ALA B N 1 ATOM 2344 C CA . ALA B 2 144 ? 22.467 -4.263 13.248 1.00 29.02 ? 314 ALA B CA 1 ATOM 2345 C C . ALA B 2 144 ? 23.343 -5.062 14.194 1.00 29.71 ? 314 ALA B C 1 ATOM 2346 O O . ALA B 2 144 ? 24.359 -4.556 14.682 1.00 30.22 ? 314 ALA B O 1 ATOM 2347 C CB . ALA B 2 144 ? 23.188 -3.987 11.986 1.00 27.11 ? 314 ALA B CB 1 ATOM 2348 N N . LEU B 2 145 ? 22.931 -6.294 14.477 1.00 27.73 ? 315 LEU B N 1 ATOM 2349 C CA . LEU B 2 145 ? 23.728 -7.179 15.300 1.00 27.77 ? 315 LEU B CA 1 ATOM 2350 C C . LEU B 2 145 ? 24.554 -8.113 14.412 1.00 27.10 ? 315 LEU B C 1 ATOM 2351 O O . LEU B 2 145 ? 24.055 -9.141 13.947 1.00 25.73 ? 315 LEU B O 1 ATOM 2352 C CB . LEU B 2 145 ? 22.832 -7.953 16.281 1.00 28.19 ? 315 LEU B CB 1 ATOM 2353 C CG . LEU B 2 145 ? 21.847 -7.112 17.112 1.00 29.66 ? 315 LEU B CG 1 ATOM 2354 C CD1 . LEU B 2 145 ? 20.989 -8.000 18.003 1.00 28.62 ? 315 LEU B CD1 1 ATOM 2355 C CD2 . LEU B 2 145 ? 22.568 -6.008 17.926 1.00 29.62 ? 315 LEU B CD2 1 ATOM 2356 N N . GLY B 2 146 ? 25.815 -7.736 14.181 1.00 26.35 ? 316 GLY B N 1 ATOM 2357 C CA . GLY B 2 146 ? 26.727 -8.507 13.321 1.00 25.69 ? 316 GLY B CA 1 ATOM 2358 C C . GLY B 2 146 ? 27.564 -9.538 14.062 1.00 24.06 ? 316 GLY B C 1 ATOM 2359 O O . GLY B 2 146 ? 27.146 -10.064 15.083 1.00 24.53 ? 316 GLY B O 1 ATOM 2360 N N . ALA B 2 147 ? 28.766 -9.800 13.557 1.00 24.03 ? 317 ALA B N 1 ATOM 2361 C CA . ALA B 2 147 ? 29.642 -10.845 14.088 1.00 23.23 ? 317 ALA B CA 1 ATOM 2362 C C . ALA B 2 147 ? 29.986 -10.679 15.576 1.00 25.58 ? 317 ALA B C 1 ATOM 2363 O O . ALA B 2 147 ? 30.097 -11.677 16.315 1.00 27.57 ? 317 ALA B O 1 ATOM 2364 C CB . ALA B 2 147 ? 30.914 -10.926 13.243 1.00 24.27 ? 317 ALA B CB 1 ATOM 2365 N N . THR B 2 148 ? 30.156 -9.428 16.009 1.00 24.35 ? 318 THR B N 1 ATOM 2366 C CA . THR B 2 148 ? 30.395 -9.091 17.420 1.00 25.28 ? 318 THR B CA 1 ATOM 2367 C C . THR B 2 148 ? 29.370 -9.782 18.324 1.00 25.36 ? 318 THR B C 1 ATOM 2368 O O . THR B 2 148 ? 29.711 -10.341 19.388 1.00 24.90 ? 318 THR B O 1 ATOM 2369 C CB . THR B 2 148 ? 30.342 -7.569 17.613 1.00 27.09 ? 318 THR B CB 1 ATOM 2370 O OG1 . THR B 2 148 ? 31.331 -6.958 16.771 1.00 28.42 ? 318 THR B OG1 1 ATOM 2371 C CG2 . THR B 2 148 ? 30.587 -7.160 19.068 1.00 27.70 ? 318 THR B CG2 1 ATOM 2372 N N . PHE B 2 149 ? 28.122 -9.782 17.863 1.00 25.31 ? 319 PHE B N 1 ATOM 2373 C CA . PHE B 2 149 ? 27.028 -10.395 18.594 1.00 24.31 ? 319 PHE B CA 1 ATOM 2374 C C . PHE B 2 149 ? 27.018 -11.902 18.372 1.00 23.92 ? 319 PHE B C 1 ATOM 2375 O O . PHE B 2 149 ? 27.010 -12.688 19.328 1.00 21.23 ? 319 PHE B O 1 ATOM 2376 C CB . PHE B 2 149 ? 25.702 -9.774 18.166 1.00 25.22 ? 319 PHE B CB 1 ATOM 2377 C CG . PHE B 2 149 ? 24.563 -10.096 19.092 1.00 27.29 ? 319 PHE B CG 1 ATOM 2378 C CD1 . PHE B 2 149 ? 23.701 -11.152 18.811 1.00 25.40 ? 319 PHE B CD1 1 ATOM 2379 C CD2 . PHE B 2 149 ? 24.366 -9.353 20.264 1.00 26.71 ? 319 PHE B CD2 1 ATOM 2380 C CE1 . PHE B 2 149 ? 22.653 -11.459 19.680 1.00 25.37 ? 319 PHE B CE1 1 ATOM 2381 C CE2 . PHE B 2 149 ? 23.325 -9.649 21.131 1.00 24.89 ? 319 PHE B CE2 1 ATOM 2382 C CZ . PHE B 2 149 ? 22.463 -10.699 20.836 1.00 25.91 ? 319 PHE B CZ 1 ATOM 2383 N N . ILE B 2 150 ? 27.054 -12.300 17.100 1.00 23.69 ? 320 ILE B N 1 ATOM 2384 C CA . ILE B 2 150 ? 26.944 -13.703 16.733 1.00 23.58 ? 320 ILE B CA 1 ATOM 2385 C C . ILE B 2 150 ? 28.059 -14.569 17.367 1.00 24.33 ? 320 ILE B C 1 ATOM 2386 O O . ILE B 2 150 ? 27.799 -15.703 17.798 1.00 23.90 ? 320 ILE B O 1 ATOM 2387 C CB . ILE B 2 150 ? 26.827 -13.864 15.204 1.00 24.16 ? 320 ILE B CB 1 ATOM 2388 C CG1 . ILE B 2 150 ? 25.535 -13.213 14.725 1.00 24.43 ? 320 ILE B CG1 1 ATOM 2389 C CG2 . ILE B 2 150 ? 26.830 -15.353 14.802 1.00 24.70 ? 320 ILE B CG2 1 ATOM 2390 C CD1 . ILE B 2 150 ? 25.644 -12.569 13.350 1.00 26.90 ? 320 ILE B CD1 1 ATOM 2391 N N . ARG B 2 151 ? 29.280 -14.033 17.451 1.00 23.85 ? 321 ARG B N 1 ATOM 2392 C CA . ARG B 2 151 ? 30.367 -14.702 18.194 1.00 23.72 ? 321 ARG B CA 1 ATOM 2393 C C . ARG B 2 151 ? 29.923 -15.210 19.568 1.00 25.38 ? 321 ARG B C 1 ATOM 2394 O O . ARG B 2 151 ? 30.215 -16.345 19.941 1.00 23.44 ? 321 ARG B O 1 ATOM 2395 C CB . ARG B 2 151 ? 31.567 -13.781 18.381 1.00 21.68 ? 321 ARG B CB 1 ATOM 2396 C CG . ARG B 2 151 ? 32.589 -13.850 17.278 1.00 24.17 ? 321 ARG B CG 1 ATOM 2397 C CD . ARG B 2 151 ? 33.916 -13.232 17.703 1.00 23.60 ? 321 ARG B CD 1 ATOM 2398 N NE . ARG B 2 151 ? 33.821 -11.779 17.841 1.00 26.51 ? 321 ARG B NE 1 ATOM 2399 C CZ . ARG B 2 151 ? 33.925 -10.912 16.832 1.00 25.83 ? 321 ARG B CZ 1 ATOM 2400 N NH1 . ARG B 2 151 ? 34.120 -11.344 15.599 1.00 26.06 ? 321 ARG B NH1 1 ATOM 2401 N NH2 . ARG B 2 151 ? 33.825 -9.610 17.058 1.00 23.65 ? 321 ARG B NH2 1 ATOM 2402 N N . LYS B 2 152 ? 29.231 -14.352 20.321 1.00 26.44 ? 322 LYS B N 1 ATOM 2403 C CA . LYS B 2 152 ? 28.786 -14.722 21.646 1.00 26.39 ? 322 LYS B CA 1 ATOM 2404 C C . LYS B 2 152 ? 27.523 -15.570 21.645 1.00 25.54 ? 322 LYS B C 1 ATOM 2405 O O . LYS B 2 152 ? 27.388 -16.473 22.466 1.00 23.96 ? 322 LYS B O 1 ATOM 2406 C CB . LYS B 2 152 ? 28.605 -13.508 22.552 1.00 25.99 ? 322 LYS B CB 1 ATOM 2407 C CG . LYS B 2 152 ? 28.695 -13.958 24.012 1.00 28.02 ? 322 LYS B CG 1 ATOM 2408 C CD . LYS B 2 152 ? 28.549 -12.843 24.984 1.00 29.14 ? 322 LYS B CD 1 ATOM 2409 C CE . LYS B 2 152 ? 28.699 -13.385 26.368 1.00 32.00 ? 322 LYS B CE 1 ATOM 2410 N NZ . LYS B 2 152 ? 29.702 -12.580 27.126 1.00 35.61 ? 322 LYS B NZ 1 ATOM 2411 N N . PHE B 2 153 ? 26.615 -15.278 20.719 1.00 26.21 ? 323 PHE B N 1 ATOM 2412 C CA . PHE B 2 153 ? 25.321 -15.935 20.681 1.00 26.76 ? 323 PHE B CA 1 ATOM 2413 C C . PHE B 2 153 ? 25.099 -16.686 19.366 1.00 27.94 ? 323 PHE B C 1 ATOM 2414 O O . PHE B 2 153 ? 24.890 -16.086 18.305 1.00 27.88 ? 323 PHE B O 1 ATOM 2415 C CB . PHE B 2 153 ? 24.203 -14.929 21.004 1.00 27.44 ? 323 PHE B CB 1 ATOM 2416 C CG . PHE B 2 153 ? 24.416 -14.188 22.320 1.00 28.79 ? 323 PHE B CG 1 ATOM 2417 C CD1 . PHE B 2 153 ? 24.463 -14.879 23.532 1.00 29.55 ? 323 PHE B CD1 1 ATOM 2418 C CD2 . PHE B 2 153 ? 24.589 -12.809 22.342 1.00 28.98 ? 323 PHE B CD2 1 ATOM 2419 C CE1 . PHE B 2 153 ? 24.672 -14.206 24.747 1.00 30.04 ? 323 PHE B CE1 1 ATOM 2420 C CE2 . PHE B 2 153 ? 24.800 -12.129 23.551 1.00 30.76 ? 323 PHE B CE2 1 ATOM 2421 C CZ . PHE B 2 153 ? 24.846 -12.834 24.758 1.00 29.17 ? 323 PHE B CZ 1 ATOM 2422 N N . TYR B 2 154 ? 25.215 -18.011 19.446 1.00 28.53 ? 324 TYR B N 1 ATOM 2423 C CA . TYR B 2 154 ? 24.856 -18.901 18.354 1.00 28.50 ? 324 TYR B CA 1 ATOM 2424 C C . TYR B 2 154 ? 23.463 -18.493 17.879 1.00 30.06 ? 324 TYR B C 1 ATOM 2425 O O . TYR B 2 154 ? 22.546 -18.316 18.697 1.00 29.27 ? 324 TYR B O 1 ATOM 2426 C CB . TYR B 2 154 ? 24.845 -20.350 18.847 1.00 29.11 ? 324 TYR B CB 1 ATOM 2427 C CG . TYR B 2 154 ? 24.734 -21.397 17.755 1.00 29.76 ? 324 TYR B CG 1 ATOM 2428 C CD1 . TYR B 2 154 ? 23.483 -21.812 17.275 1.00 29.96 ? 324 TYR B CD1 1 ATOM 2429 C CD2 . TYR B 2 154 ? 25.874 -21.977 17.208 1.00 29.17 ? 324 TYR B CD2 1 ATOM 2430 C CE1 . TYR B 2 154 ? 23.384 -22.787 16.282 1.00 29.00 ? 324 TYR B CE1 1 ATOM 2431 C CE2 . TYR B 2 154 ? 25.789 -22.938 16.207 1.00 29.11 ? 324 TYR B CE2 1 ATOM 2432 C CZ . TYR B 2 154 ? 24.545 -23.336 15.750 1.00 29.62 ? 324 TYR B CZ 1 ATOM 2433 O OH . TYR B 2 154 ? 24.471 -24.278 14.759 1.00 30.12 ? 324 TYR B OH 1 ATOM 2434 N N . THR B 2 155 ? 23.318 -18.310 16.568 1.00 30.76 ? 325 THR B N 1 ATOM 2435 C CA . THR B 2 155 ? 22.067 -17.793 16.014 1.00 30.63 ? 325 THR B CA 1 ATOM 2436 C C . THR B 2 155 ? 21.417 -18.745 15.009 1.00 30.35 ? 325 THR B C 1 ATOM 2437 O O . THR B 2 155 ? 22.064 -19.231 14.087 1.00 30.09 ? 325 THR B O 1 ATOM 2438 C CB . THR B 2 155 ? 22.257 -16.398 15.392 1.00 29.01 ? 325 THR B CB 1 ATOM 2439 O OG1 . THR B 2 155 ? 22.883 -15.532 16.344 1.00 29.22 ? 325 THR B OG1 1 ATOM 2440 C CG2 . THR B 2 155 ? 20.934 -15.813 15.030 1.00 29.35 ? 325 THR B CG2 1 ATOM 2441 N N . GLU B 2 156 ? 20.130 -19.003 15.218 1.00 31.77 ? 326 GLU B N 1 ATOM 2442 C CA . GLU B 2 156 ? 19.320 -19.802 14.306 1.00 32.09 ? 326 GLU B CA 1 ATOM 2443 C C . GLU B 2 156 ? 18.302 -18.937 13.575 1.00 31.04 ? 326 GLU B C 1 ATOM 2444 O O . GLU B 2 156 ? 17.561 -18.190 14.198 1.00 30.94 ? 326 GLU B O 1 ATOM 2445 C CB . GLU B 2 156 ? 18.587 -20.902 15.065 1.00 33.53 ? 326 GLU B CB 1 ATOM 2446 C CG . GLU B 2 156 ? 17.833 -21.829 14.139 1.00 37.87 ? 326 GLU B CG 1 ATOM 2447 C CD . GLU B 2 156 ? 17.082 -22.907 14.876 1.00 41.25 ? 326 GLU B CD 1 ATOM 2448 O OE1 . GLU B 2 156 ? 15.829 -22.868 14.867 1.00 43.96 ? 326 GLU B OE1 1 ATOM 2449 O OE2 . GLU B 2 156 ? 17.745 -23.786 15.465 1.00 42.09 ? 326 GLU B OE2 1 ATOM 2450 N N . PHE B 2 157 ? 18.260 -19.056 12.253 1.00 30.47 ? 327 PHE B N 1 ATOM 2451 C CA . PHE B 2 157 ? 17.305 -18.316 11.440 1.00 28.59 ? 327 PHE B CA 1 ATOM 2452 C C . PHE B 2 157 ? 16.276 -19.317 10.945 1.00 30.63 ? 327 PHE B C 1 ATOM 2453 O O . PHE B 2 157 ? 16.610 -20.275 10.254 1.00 31.94 ? 327 PHE B O 1 ATOM 2454 C CB . PHE B 2 157 ? 18.025 -17.598 10.294 1.00 27.03 ? 327 PHE B CB 1 ATOM 2455 C CG . PHE B 2 157 ? 19.100 -16.648 10.764 1.00 25.61 ? 327 PHE B CG 1 ATOM 2456 C CD1 . PHE B 2 157 ? 18.814 -15.302 10.963 1.00 23.96 ? 327 PHE B CD1 1 ATOM 2457 C CD2 . PHE B 2 157 ? 20.376 -17.115 11.074 1.00 25.87 ? 327 PHE B CD2 1 ATOM 2458 C CE1 . PHE B 2 157 ? 19.784 -14.426 11.428 1.00 25.38 ? 327 PHE B CE1 1 ATOM 2459 C CE2 . PHE B 2 157 ? 21.358 -16.241 11.542 1.00 27.68 ? 327 PHE B CE2 1 ATOM 2460 C CZ . PHE B 2 157 ? 21.059 -14.885 11.717 1.00 26.36 ? 327 PHE B CZ 1 ATOM 2461 N N . ASP B 2 158 ? 15.025 -19.100 11.339 1.00 32.58 ? 328 ASP B N 1 ATOM 2462 C CA . ASP B 2 158 ? 13.963 -20.083 11.184 1.00 33.11 ? 328 ASP B CA 1 ATOM 2463 C C . ASP B 2 158 ? 12.897 -19.561 10.239 1.00 33.24 ? 328 ASP B C 1 ATOM 2464 O O . ASP B 2 158 ? 12.174 -18.629 10.576 1.00 34.42 ? 328 ASP B O 1 ATOM 2465 C CB . ASP B 2 158 ? 13.370 -20.398 12.561 1.00 35.32 ? 328 ASP B CB 1 ATOM 2466 C CG . ASP B 2 158 ? 12.210 -21.380 12.507 1.00 36.88 ? 328 ASP B CG 1 ATOM 2467 O OD1 . ASP B 2 158 ? 11.575 -21.539 11.443 1.00 39.04 ? 328 ASP B OD1 1 ATOM 2468 O OD2 . ASP B 2 158 ? 11.919 -21.985 13.559 1.00 37.75 ? 328 ASP B OD2 1 ATOM 2469 N N . ARG B 2 159 ? 12.801 -20.174 9.060 1.00 33.95 ? 329 ARG B N 1 ATOM 2470 C CA . ARG B 2 159 ? 11.897 -19.700 8.000 1.00 34.25 ? 329 ARG B CA 1 ATOM 2471 C C . ARG B 2 159 ? 10.495 -20.294 8.122 1.00 34.37 ? 329 ARG B C 1 ATOM 2472 O O . ARG B 2 159 ? 9.504 -19.678 7.718 1.00 33.99 ? 329 ARG B O 1 ATOM 2473 C CB . ARG B 2 159 ? 12.483 -20.010 6.616 1.00 33.90 ? 329 ARG B CB 1 ATOM 2474 C CG . ARG B 2 159 ? 13.562 -19.051 6.161 1.00 34.85 ? 329 ARG B CG 1 ATOM 2475 C CD . ARG B 2 159 ? 13.012 -17.692 5.778 1.00 35.43 ? 329 ARG B CD 1 ATOM 2476 N NE . ARG B 2 159 ? 12.039 -17.756 4.683 1.00 36.63 ? 329 ARG B NE 1 ATOM 2477 C CZ . ARG B 2 159 ? 12.344 -17.725 3.388 1.00 36.29 ? 329 ARG B CZ 1 ATOM 2478 N NH1 . ARG B 2 159 ? 13.608 -17.624 2.981 1.00 36.32 ? 329 ARG B NH1 1 ATOM 2479 N NH2 . ARG B 2 159 ? 11.377 -17.798 2.491 1.00 35.41 ? 329 ARG B NH2 1 ATOM 2480 N N . ARG B 2 160 ? 10.435 -21.510 8.653 1.00 34.60 ? 330 ARG B N 1 ATOM 2481 C CA . ARG B 2 160 ? 9.188 -22.172 8.966 1.00 34.60 ? 330 ARG B CA 1 ATOM 2482 C C . ARG B 2 160 ? 8.335 -21.325 9.901 1.00 35.15 ? 330 ARG B C 1 ATOM 2483 O O . ARG B 2 160 ? 7.166 -21.097 9.607 1.00 36.62 ? 330 ARG B O 1 ATOM 2484 C CB . ARG B 2 160 ? 9.469 -23.523 9.617 1.00 35.32 ? 330 ARG B CB 1 ATOM 2485 C CG . ARG B 2 160 ? 8.230 -24.278 10.097 1.00 34.36 ? 330 ARG B CG 1 ATOM 2486 C CD . ARG B 2 160 ? 7.500 -24.875 8.931 1.00 32.66 ? 330 ARG B CD 1 ATOM 2487 N NE . ARG B 2 160 ? 6.354 -25.672 9.339 1.00 31.59 ? 330 ARG B NE 1 ATOM 2488 C CZ . ARG B 2 160 ? 5.228 -25.763 8.641 1.00 30.67 ? 330 ARG B CZ 1 ATOM 2489 N NH1 . ARG B 2 160 ? 5.089 -25.081 7.497 1.00 28.98 ? 330 ARG B NH1 1 ATOM 2490 N NH2 . ARG B 2 160 ? 4.239 -26.520 9.097 1.00 27.42 ? 330 ARG B NH2 1 ATOM 2491 N N . ASN B 2 161 ? 8.916 -20.865 11.015 1.00 34.81 ? 331 ASN B N 1 ATOM 2492 C CA . ASN B 2 161 ? 8.161 -20.125 12.038 1.00 34.91 ? 331 ASN B CA 1 ATOM 2493 C C . ASN B 2 161 ? 8.359 -18.598 12.016 1.00 36.42 ? 331 ASN B C 1 ATOM 2494 O O . ASN B 2 161 ? 7.793 -17.888 12.848 1.00 36.60 ? 331 ASN B O 1 ATOM 2495 C CB . ASN B 2 161 ? 8.474 -20.664 13.435 1.00 33.40 ? 331 ASN B CB 1 ATOM 2496 C CG . ASN B 2 161 ? 8.205 -22.151 13.571 1.00 33.20 ? 331 ASN B CG 1 ATOM 2497 O OD1 . ASN B 2 161 ? 9.128 -22.944 13.700 1.00 31.60 ? 331 ASN B OD1 1 ATOM 2498 N ND2 . ASN B 2 161 ? 6.935 -22.534 13.549 1.00 33.92 ? 331 ASN B ND2 1 ATOM 2499 N N . ASN B 2 162 ? 9.144 -18.103 11.059 1.00 37.24 ? 332 ASN B N 1 ATOM 2500 C CA . ASN B 2 162 ? 9.568 -16.698 11.015 1.00 37.47 ? 332 ASN B CA 1 ATOM 2501 C C . ASN B 2 162 ? 10.092 -16.195 12.359 1.00 36.77 ? 332 ASN B C 1 ATOM 2502 O O . ASN B 2 162 ? 9.589 -15.220 12.926 1.00 36.85 ? 332 ASN B O 1 ATOM 2503 C CB . ASN B 2 162 ? 8.463 -15.781 10.490 1.00 39.63 ? 332 ASN B CB 1 ATOM 2504 C CG . ASN B 2 162 ? 8.239 -15.927 9.004 1.00 41.46 ? 332 ASN B CG 1 ATOM 2505 O OD1 . ASN B 2 162 ? 9.074 -15.515 8.189 1.00 42.83 ? 332 ASN B OD1 1 ATOM 2506 N ND2 . ASN B 2 162 ? 7.093 -16.498 8.634 1.00 41.97 ? 332 ASN B ND2 1 ATOM 2507 N N . ARG B 2 163 ? 11.111 -16.871 12.871 1.00 34.21 ? 333 ARG B N 1 ATOM 2508 C CA . ARG B 2 163 ? 11.748 -16.417 14.102 1.00 31.45 ? 333 ARG B CA 1 ATOM 2509 C C . ARG B 2 163 ? 13.276 -16.480 14.024 1.00 29.83 ? 333 ARG B C 1 ATOM 2510 O O . ARG B 2 163 ? 13.854 -17.083 13.107 1.00 27.79 ? 333 ARG B O 1 ATOM 2511 C CB . ARG B 2 163 ? 11.215 -17.198 15.309 1.00 29.95 ? 333 ARG B CB 1 ATOM 2512 C CG . ARG B 2 163 ? 11.442 -18.696 15.223 1.00 30.43 ? 333 ARG B CG 1 ATOM 2513 C CD . ARG B 2 163 ? 10.540 -19.451 16.166 1.00 28.31 ? 333 ARG B CD 1 ATOM 2514 N NE . ARG B 2 163 ? 10.955 -20.846 16.258 1.00 28.77 ? 333 ARG B NE 1 ATOM 2515 C CZ . ARG B 2 163 ? 10.808 -21.615 17.337 1.00 28.54 ? 333 ARG B CZ 1 ATOM 2516 N NH1 . ARG B 2 163 ? 10.255 -21.131 18.430 1.00 29.20 ? 333 ARG B NH1 1 ATOM 2517 N NH2 . ARG B 2 163 ? 11.231 -22.873 17.330 1.00 28.88 ? 333 ARG B NH2 1 ATOM 2518 N N . ILE B 2 164 ? 13.919 -15.814 14.979 1.00 29.30 ? 334 ILE B N 1 ATOM 2519 C CA . ILE B 2 164 ? 15.360 -15.942 15.179 1.00 27.16 ? 334 ILE B CA 1 ATOM 2520 C C . ILE B 2 164 ? 15.628 -16.484 16.584 1.00 27.36 ? 334 ILE B C 1 ATOM 2521 O O . ILE B 2 164 ? 15.071 -15.988 17.569 1.00 27.52 ? 334 ILE B O 1 ATOM 2522 C CB . ILE B 2 164 ? 16.083 -14.606 14.957 1.00 25.90 ? 334 ILE B CB 1 ATOM 2523 C CG1 . ILE B 2 164 ? 15.911 -14.142 13.503 1.00 25.94 ? 334 ILE B CG1 1 ATOM 2524 C CG2 . ILE B 2 164 ? 17.539 -14.741 15.290 1.00 25.77 ? 334 ILE B CG2 1 ATOM 2525 C CD1 . ILE B 2 164 ? 16.313 -12.682 13.254 1.00 25.92 ? 334 ILE B CD1 1 ATOM 2526 N N . GLY B 2 165 ? 16.487 -17.488 16.675 1.00 27.78 ? 335 GLY B N 1 ATOM 2527 C CA . GLY B 2 165 ? 16.809 -18.099 17.954 1.00 29.41 ? 335 GLY B CA 1 ATOM 2528 C C . GLY B 2 165 ? 18.232 -17.849 18.391 1.00 31.37 ? 335 GLY B C 1 ATOM 2529 O O . GLY B 2 165 ? 19.156 -17.992 17.587 1.00 32.86 ? 335 GLY B O 1 ATOM 2530 N N . PHE B 2 166 ? 18.412 -17.486 19.667 1.00 30.25 ? 336 PHE B N 1 ATOM 2531 C CA . PHE B 2 166 ? 19.746 -17.294 20.242 1.00 28.65 ? 336 PHE B CA 1 ATOM 2532 C C . PHE B 2 166 ? 20.047 -18.261 21.375 1.00 29.64 ? 336 PHE B C 1 ATOM 2533 O O . PHE B 2 166 ? 19.237 -18.436 22.274 1.00 31.78 ? 336 PHE B O 1 ATOM 2534 C CB . PHE B 2 166 ? 19.934 -15.872 20.764 1.00 27.95 ? 336 PHE B CB 1 ATOM 2535 C CG . PHE B 2 166 ? 19.822 -14.793 19.711 1.00 26.68 ? 336 PHE B CG 1 ATOM 2536 C CD1 . PHE B 2 166 ? 20.732 -14.715 18.666 1.00 25.58 ? 336 PHE B CD1 1 ATOM 2537 C CD2 . PHE B 2 166 ? 18.834 -13.817 19.812 1.00 25.37 ? 336 PHE B CD2 1 ATOM 2538 C CE1 . PHE B 2 166 ? 20.647 -13.700 17.720 1.00 25.13 ? 336 PHE B CE1 1 ATOM 2539 C CE2 . PHE B 2 166 ? 18.733 -12.807 18.871 1.00 25.93 ? 336 PHE B CE2 1 ATOM 2540 C CZ . PHE B 2 166 ? 19.646 -12.752 17.816 1.00 26.07 ? 336 PHE B CZ 1 ATOM 2541 N N . ALA B 2 167 ? 21.223 -18.885 21.321 1.00 30.53 ? 337 ALA B N 1 ATOM 2542 C CA . ALA B 2 167 ? 21.749 -19.706 22.415 1.00 30.26 ? 337 ALA B CA 1 ATOM 2543 C C . ALA B 2 167 ? 23.198 -19.300 22.677 1.00 30.33 ? 337 ALA B C 1 ATOM 2544 O O . ALA B 2 167 ? 23.836 -18.716 21.809 1.00 30.26 ? 337 ALA B O 1 ATOM 2545 C CB . ALA B 2 167 ? 21.651 -21.181 22.069 1.00 29.30 ? 337 ALA B CB 1 ATOM 2546 N N . LEU B 2 168 ? 23.715 -19.588 23.869 1.00 33.56 ? 338 LEU B N 1 ATOM 2547 C CA . LEU B 2 168 ? 25.087 -19.193 24.229 1.00 35.83 ? 338 LEU B CA 1 ATOM 2548 C C . LEU B 2 168 ? 26.076 -20.020 23.429 1.00 37.68 ? 338 LEU B C 1 ATOM 2549 O O . LEU B 2 168 ? 26.047 -21.250 23.503 1.00 38.56 ? 338 LEU B O 1 ATOM 2550 C CB . LEU B 2 168 ? 25.352 -19.429 25.713 1.00 36.63 ? 338 LEU B CB 1 ATOM 2551 C CG . LEU B 2 168 ? 26.119 -18.411 26.575 1.00 38.70 ? 338 LEU B CG 1 ATOM 2552 C CD1 . LEU B 2 168 ? 26.619 -19.105 27.844 1.00 39.73 ? 338 LEU B CD1 1 ATOM 2553 C CD2 . LEU B 2 168 ? 27.275 -17.708 25.870 1.00 37.23 ? 338 LEU B CD2 1 ATOM 2554 N N . ALA B 2 169 ? 26.948 -19.366 22.666 1.00 37.31 ? 339 ALA B N 1 ATOM 2555 C CA . ALA B 2 169 ? 27.920 -20.115 21.870 1.00 38.05 ? 339 ALA B CA 1 ATOM 2556 C C . ALA B 2 169 ? 28.952 -20.778 22.773 1.00 39.44 ? 339 ALA B C 1 ATOM 2557 O O . ALA B 2 169 ? 29.408 -20.181 23.757 1.00 38.64 ? 339 ALA B O 1 ATOM 2558 C CB . ALA B 2 169 ? 28.594 -19.228 20.829 1.00 35.74 ? 339 ALA B CB 1 ATOM 2559 N N . ARG B 2 170 ? 29.274 -22.026 22.446 1.00 43.22 ? 340 ARG B N 1 ATOM 2560 C CA . ARG B 2 170 ? 30.344 -22.776 23.101 1.00 48.24 ? 340 ARG B CA 1 ATOM 2561 C C . ARG B 2 170 ? 31.630 -22.686 22.280 1.00 50.54 ? 340 ARG B C 1 ATOM 2562 O O . ARG B 2 170 ? 31.718 -23.234 21.164 1.00 51.49 ? 340 ARG B O 1 ATOM 2563 C CB . ARG B 2 170 ? 29.949 -24.246 23.282 1.00 50.44 ? 340 ARG B CB 1 ATOM 2564 C CG . ARG B 2 170 ? 29.305 -24.578 24.613 1.00 53.68 ? 340 ARG B CG 1 ATOM 2565 C CD . ARG B 2 170 ? 29.331 -26.094 24.873 1.00 56.06 ? 340 ARG B CD 1 ATOM 2566 N NE . ARG B 2 170 ? 28.072 -26.762 24.527 1.00 57.04 ? 340 ARG B NE 1 ATOM 2567 C CZ . ARG B 2 170 ? 27.312 -27.453 25.381 1.00 58.61 ? 340 ARG B CZ 1 ATOM 2568 N NH1 . ARG B 2 170 ? 27.667 -27.590 26.657 1.00 58.71 ? 340 ARG B NH1 1 ATOM 2569 N NH2 . ARG B 2 170 ? 26.187 -28.021 24.958 1.00 58.90 ? 340 ARG B NH2 1 ATOM 2570 N N . HIS B 2 171 ? 32.621 -21.995 22.835 1.00 51.69 ? 341 HIS B N 1 ATOM 2571 C CA . HIS B 2 171 ? 33.932 -21.883 22.203 1.00 52.71 ? 341 HIS B CA 1 ATOM 2572 C C . HIS B 2 171 ? 34.941 -22.833 22.851 1.00 53.26 ? 341 HIS B C 1 ATOM 2573 O O . HIS B 2 171 ? 35.543 -23.669 22.165 1.00 53.98 ? 341 HIS B O 1 ATOM 2574 C CB . HIS B 2 171 ? 34.441 -20.441 22.258 1.00 52.13 ? 341 HIS B CB 1 ATOM 2575 C CG . HIS B 2 171 ? 33.597 -19.473 21.490 1.00 51.68 ? 341 HIS B CG 1 ATOM 2576 N ND1 . HIS B 2 171 ? 32.567 -18.764 22.069 1.00 51.47 ? 341 HIS B ND1 1 ATOM 2577 C CD2 . HIS B 2 171 ? 33.635 -19.090 20.192 1.00 50.92 ? 341 HIS B CD2 1 ATOM 2578 C CE1 . HIS B 2 171 ? 32.006 -17.987 21.160 1.00 51.01 ? 341 HIS B CE1 1 ATOM 2579 N NE2 . HIS B 2 171 ? 32.635 -18.165 20.012 1.00 49.81 ? 341 HIS B NE2 1 ATOM 2580 N N . LEU C 1 1 ? 61.223 9.117 -36.163 1.00 30.55 ? 1 LEU C N 1 ATOM 2581 C CA . LEU C 1 1 ? 60.892 9.663 -37.505 1.00 31.54 ? 1 LEU C CA 1 ATOM 2582 C C . LEU C 1 1 ? 59.423 9.435 -37.794 1.00 33.72 ? 1 LEU C C 1 ATOM 2583 O O . LEU C 1 1 ? 58.887 8.343 -37.566 1.00 32.98 ? 1 LEU C O 1 ATOM 2584 C CB . LEU C 1 1 ? 61.743 9.016 -38.613 1.00 28.72 ? 1 LEU C CB 1 ATOM 2585 C CG . LEU C 1 1 ? 63.274 9.031 -38.544 1.00 29.00 ? 1 LEU C CG 1 ATOM 2586 C CD1 . LEU C 1 1 ? 63.853 8.241 -39.694 1.00 28.17 ? 1 LEU C CD1 1 ATOM 2587 C CD2 . LEU C 1 1 ? 63.856 10.434 -38.538 1.00 28.79 ? 1 LEU C CD2 1 ATOM 2588 N N . THR C 1 2 ? 58.785 10.481 -38.309 1.00 36.69 ? 2 THR C N 1 ATOM 2589 C CA . THR C 1 2 ? 57.378 10.450 -38.682 1.00 39.47 ? 2 THR C CA 1 ATOM 2590 C C . THR C 1 2 ? 57.174 10.970 -40.097 1.00 41.94 ? 2 THR C C 1 ATOM 2591 O O . THR C 1 2 ? 58.070 11.561 -40.701 1.00 43.33 ? 2 THR C O 1 ATOM 2592 C CB . THR C 1 2 ? 56.510 11.283 -37.700 1.00 40.36 ? 2 THR C CB 1 ATOM 2593 O OG1 . THR C 1 2 ? 55.359 11.789 -38.382 1.00 41.92 ? 2 THR C OG1 1 ATOM 2594 C CG2 . THR C 1 2 ? 57.274 12.461 -37.168 1.00 41.62 ? 2 THR C CG2 1 ATOM 2595 N N . LEU C 1 3 ? 55.968 10.755 -40.602 1.00 43.69 ? 3 LEU C N 1 ATOM 2596 C CA . LEU C 1 3 ? 55.550 11.228 -41.905 1.00 45.71 ? 3 LEU C CA 1 ATOM 2597 C C . LEU C 1 3 ? 54.214 11.968 -41.741 1.00 46.34 ? 3 LEU C C 1 ATOM 2598 O O . LEU C 1 3 ? 53.465 12.086 -42.705 1.00 45.98 ? 3 LEU C O 1 ATOM 2599 C CB . LEU C 1 3 ? 55.362 10.013 -42.828 1.00 45.03 ? 3 LEU C CB 1 ATOM 2600 C CG . LEU C 1 3 ? 56.445 9.308 -43.664 1.00 45.82 ? 3 LEU C CG 1 ATOM 2601 C CD1 . LEU C 1 3 ? 57.893 9.719 -43.400 1.00 45.92 ? 3 LEU C CD1 1 ATOM 2602 C CD2 . LEU C 1 3 ? 56.289 7.794 -43.563 1.00 46.02 ? 3 LEU C CD2 1 ATOM 2603 N N . GLY C 1 4 ? 53.959 12.486 -40.529 1.00 48.17 ? 4 GLY C N 1 ATOM 2604 C CA . GLY C 1 4 ? 52.599 12.738 -39.970 1.00 49.76 ? 4 GLY C CA 1 ATOM 2605 C C . GLY C 1 4 ? 51.550 12.605 -41.043 1.00 49.57 ? 4 GLY C C 1 ATOM 2606 O O . GLY C 1 4 ? 51.071 13.619 -41.556 1.00 52.65 ? 4 GLY C O 1 ATOM 2607 N N . ASN C 1 5 ? 51.097 11.393 -41.367 1.00 48.48 ? 5 ASN C N 1 ATOM 2608 C CA . ASN C 1 5 ? 50.212 10.494 -40.608 1.00 46.67 ? 5 ASN C CA 1 ATOM 2609 C C . ASN C 1 5 ? 50.324 9.774 -39.230 1.00 42.95 ? 5 ASN C C 1 ATOM 2610 O O . ASN C 1 5 ? 49.651 8.749 -39.069 1.00 41.80 ? 5 ASN C O 1 ATOM 2611 C CB . ASN C 1 5 ? 49.894 9.384 -41.627 1.00 50.42 ? 5 ASN C CB 1 ATOM 2612 C CG . ASN C 1 5 ? 48.424 9.280 -41.947 1.00 54.03 ? 5 ASN C CG 1 ATOM 2613 O OD1 . ASN C 1 5 ? 47.656 10.212 -41.709 1.00 52.15 ? 5 ASN C OD1 1 ATOM 2614 N ND2 . ASN C 1 5 ? 48.033 8.144 -42.531 1.00 58.05 ? 5 ASN C ND2 1 ATOM 2615 N N . THR C 1 6 ? 51.058 10.252 -38.227 1.00 39.42 ? 6 THR C N 1 ATOM 2616 C CA . THR C 1 6 ? 51.095 9.452 -36.962 1.00 35.62 ? 6 THR C CA 1 ATOM 2617 C C . THR C 1 6 ? 50.109 9.857 -35.848 1.00 34.88 ? 6 THR C C 1 ATOM 2618 O O . THR C 1 6 ? 50.011 11.033 -35.490 1.00 34.20 ? 6 THR C O 1 ATOM 2619 C CB . THR C 1 6 ? 52.518 9.288 -36.389 1.00 34.23 ? 6 THR C CB 1 ATOM 2620 O OG1 . THR C 1 6 ? 53.352 8.654 -37.363 1.00 34.96 ? 6 THR C OG1 1 ATOM 2621 C CG2 . THR C 1 6 ? 52.507 8.436 -35.139 1.00 33.57 ? 6 THR C CG2 1 ATOM 2622 N N . THR C 1 7 ? 49.374 8.873 -35.327 1.00 34.58 ? 7 THR C N 1 ATOM 2623 C CA . THR C 1 7 ? 48.538 9.044 -34.123 1.00 35.20 ? 7 THR C CA 1 ATOM 2624 C C . THR C 1 7 ? 48.763 7.929 -33.077 1.00 34.77 ? 7 THR C C 1 ATOM 2625 O O . THR C 1 7 ? 49.325 6.880 -33.379 1.00 35.57 ? 7 THR C O 1 ATOM 2626 C CB . THR C 1 7 ? 47.000 9.136 -34.454 1.00 34.14 ? 7 THR C CB 1 ATOM 2627 O OG1 . THR C 1 7 ? 46.552 7.927 -35.070 1.00 33.63 ? 7 THR C OG1 1 ATOM 2628 C CG2 . THR C 1 7 ? 46.690 10.305 -35.374 1.00 32.83 ? 7 THR C CG2 1 ATOM 2629 N N . SER C 1 8 ? 48.336 8.166 -31.842 1.00 35.46 ? 8 SER C N 1 ATOM 2630 C CA . SER C 1 8 ? 48.244 7.087 -30.859 1.00 35.30 ? 8 SER C CA 1 ATOM 2631 C C . SER C 1 8 ? 46.980 7.206 -30.027 1.00 32.68 ? 8 SER C C 1 ATOM 2632 O O . SER C 1 8 ? 46.358 8.263 -29.967 1.00 34.07 ? 8 SER C O 1 ATOM 2633 C CB . SER C 1 8 ? 49.480 7.049 -29.954 1.00 37.02 ? 8 SER C CB 1 ATOM 2634 O OG . SER C 1 8 ? 49.374 7.994 -28.907 1.00 39.90 ? 8 SER C OG 1 ATOM 2635 N N . SER C 1 9 ? 46.607 6.124 -29.365 1.00 32.88 ? 9 SER C N 1 ATOM 2636 C CA . SER C 1 9 ? 45.395 6.128 -28.570 1.00 32.98 ? 9 SER C CA 1 ATOM 2637 C C . SER C 1 9 ? 45.532 5.451 -27.211 1.00 33.34 ? 9 SER C C 1 ATOM 2638 O O . SER C 1 9 ? 46.354 4.543 -27.025 1.00 31.65 ? 9 SER C O 1 ATOM 2639 C CB . SER C 1 9 ? 44.229 5.534 -29.357 1.00 31.99 ? 9 SER C CB 1 ATOM 2640 O OG . SER C 1 9 ? 44.610 4.305 -29.920 1.00 34.92 ? 9 SER C OG 1 ATOM 2641 N N . VAL C 1 10 ? 44.708 5.927 -26.272 1.00 32.60 ? 10 VAL C N 1 ATOM 2642 C CA . VAL C 1 10 ? 44.600 5.371 -24.936 1.00 31.06 ? 10 VAL C CA 1 ATOM 2643 C C . VAL C 1 10 ? 43.167 4.866 -24.751 1.00 30.93 ? 10 VAL C C 1 ATOM 2644 O O . VAL C 1 10 ? 42.211 5.620 -24.921 1.00 31.43 ? 10 VAL C O 1 ATOM 2645 C CB . VAL C 1 10 ? 44.948 6.427 -23.859 1.00 31.37 ? 10 VAL C CB 1 ATOM 2646 C CG1 . VAL C 1 10 ? 44.922 5.819 -22.477 1.00 30.64 ? 10 VAL C CG1 1 ATOM 2647 C CG2 . VAL C 1 10 ? 46.311 7.054 -24.135 1.00 30.81 ? 10 VAL C CG2 1 ATOM 2648 N N . ILE C 1 11 ? 43.035 3.579 -24.443 1.00 31.22 ? 11 ILE C N 1 ATOM 2649 C CA . ILE C 1 11 ? 41.760 2.955 -24.122 1.00 32.54 ? 11 ILE C CA 1 ATOM 2650 C C . ILE C 1 11 ? 41.360 3.324 -22.694 1.00 31.93 ? 11 ILE C C 1 ATOM 2651 O O . ILE C 1 11 ? 42.158 3.206 -21.778 1.00 32.06 ? 11 ILE C O 1 ATOM 2652 C CB . ILE C 1 11 ? 41.848 1.399 -24.206 1.00 33.00 ? 11 ILE C CB 1 ATOM 2653 C CG1 . ILE C 1 11 ? 42.298 0.924 -25.599 1.00 33.96 ? 11 ILE C CG1 1 ATOM 2654 C CG2 . ILE C 1 11 ? 40.527 0.755 -23.802 1.00 31.32 ? 11 ILE C CG2 1 ATOM 2655 C CD1 . ILE C 1 11 ? 41.329 1.226 -26.735 1.00 35.77 ? 11 ILE C CD1 1 ATOM 2656 N N . LEU C 1 12 ? 40.120 3.750 -22.507 1.00 32.21 ? 12 LEU C N 1 ATOM 2657 C CA . LEU C 1 12 ? 39.633 4.111 -21.173 1.00 29.98 ? 12 LEU C CA 1 ATOM 2658 C C . LEU C 1 12 ? 38.666 3.084 -20.625 1.00 28.85 ? 12 LEU C C 1 ATOM 2659 O O . LEU C 1 12 ? 37.954 2.429 -21.374 1.00 30.32 ? 12 LEU C O 1 ATOM 2660 C CB . LEU C 1 12 ? 38.954 5.482 -21.192 1.00 29.46 ? 12 LEU C CB 1 ATOM 2661 C CG . LEU C 1 12 ? 39.707 6.649 -21.822 1.00 29.53 ? 12 LEU C CG 1 ATOM 2662 C CD1 . LEU C 1 12 ? 38.913 7.934 -21.607 1.00 29.82 ? 12 LEU C CD1 1 ATOM 2663 C CD2 . LEU C 1 12 ? 41.113 6.776 -21.246 1.00 29.58 ? 12 LEU C CD2 1 ATOM 2664 N N . THR C 1 13 ? 38.663 2.943 -19.308 1.00 29.77 ? 13 THR C N 1 ATOM 2665 C CA . THR C 1 13 ? 37.652 2.163 -18.607 1.00 29.79 ? 13 THR C CA 1 ATOM 2666 C C . THR C 1 13 ? 36.569 3.115 -18.114 1.00 30.25 ? 13 THR C C 1 ATOM 2667 O O . THR C 1 13 ? 36.859 4.235 -17.683 1.00 29.96 ? 13 THR C O 1 ATOM 2668 C CB . THR C 1 13 ? 38.279 1.413 -17.426 1.00 28.97 ? 13 THR C CB 1 ATOM 2669 O OG1 . THR C 1 13 ? 39.294 0.545 -17.935 1.00 29.81 ? 13 THR C OG1 1 ATOM 2670 C CG2 . THR C 1 13 ? 37.237 0.586 -16.661 1.00 29.49 ? 13 THR C CG2 1 ATOM 2671 N N . ASN C 1 14 ? 35.323 2.672 -18.200 1.00 29.95 ? 14 ASN C N 1 ATOM 2672 C CA . ASN C 1 14 ? 34.207 3.458 -17.707 1.00 31.12 ? 14 ASN C CA 1 ATOM 2673 C C . ASN C 1 14 ? 33.667 2.906 -16.386 1.00 32.95 ? 14 ASN C C 1 ATOM 2674 O O . ASN C 1 14 ? 32.999 1.862 -16.364 1.00 32.14 ? 14 ASN C O 1 ATOM 2675 C CB . ASN C 1 14 ? 33.088 3.514 -18.752 1.00 29.61 ? 14 ASN C CB 1 ATOM 2676 C CG . ASN C 1 14 ? 31.863 4.217 -18.239 1.00 29.88 ? 14 ASN C CG 1 ATOM 2677 O OD1 . ASN C 1 14 ? 31.882 4.813 -17.161 1.00 28.73 ? 14 ASN C OD1 1 ATOM 2678 N ND2 . ASN C 1 14 ? 30.787 4.167 -19.008 1.00 31.67 ? 14 ASN C ND2 1 ATOM 2679 N N . TYR C 1 15 ? 33.962 3.607 -15.295 1.00 35.94 ? 15 TYR C N 1 ATOM 2680 C CA . TYR C 1 15 ? 33.417 3.243 -13.996 1.00 38.91 ? 15 TYR C CA 1 ATOM 2681 C C . TYR C 1 15 ? 32.121 3.988 -13.679 1.00 39.26 ? 15 TYR C C 1 ATOM 2682 O O . TYR C 1 15 ? 32.136 5.150 -13.263 1.00 39.09 ? 15 TYR C O 1 ATOM 2683 C CB . TYR C 1 15 ? 34.431 3.401 -12.854 1.00 41.38 ? 15 TYR C CB 1 ATOM 2684 C CG . TYR C 1 15 ? 33.801 3.088 -11.511 1.00 42.90 ? 15 TYR C CG 1 ATOM 2685 C CD1 . TYR C 1 15 ? 33.075 1.907 -11.323 1.00 43.84 ? 15 TYR C CD1 1 ATOM 2686 C CD2 . TYR C 1 15 ? 33.885 3.984 -10.447 1.00 43.98 ? 15 TYR C CD2 1 ATOM 2687 C CE1 . TYR C 1 15 ? 32.465 1.616 -10.115 1.00 44.18 ? 15 TYR C CE1 1 ATOM 2688 C CE2 . TYR C 1 15 ? 33.284 3.697 -9.222 1.00 44.83 ? 15 TYR C CE2 1 ATOM 2689 C CZ . TYR C 1 15 ? 32.581 2.510 -9.066 1.00 44.27 ? 15 TYR C CZ 1 ATOM 2690 O OH . TYR C 1 15 ? 31.975 2.218 -7.870 1.00 43.97 ? 15 TYR C OH 1 ATOM 2691 N N . MET C 1 16 ? 31.010 3.286 -13.884 1.00 39.86 ? 16 MET C N 1 ATOM 2692 C CA . MET C 1 16 ? 29.658 3.738 -13.535 1.00 40.70 ? 16 MET C CA 1 ATOM 2693 C C . MET C 1 16 ? 29.239 5.084 -14.159 1.00 36.57 ? 16 MET C C 1 ATOM 2694 O O . MET C 1 16 ? 28.426 5.807 -13.595 1.00 35.92 ? 16 MET C O 1 ATOM 2695 C CB . MET C 1 16 ? 29.406 3.661 -12.005 1.00 42.06 ? 16 MET C CB 1 ATOM 2696 C CG . MET C 1 16 ? 30.039 4.766 -11.128 1.00 45.09 ? 16 MET C CG 1 ATOM 2697 S SD . MET C 1 16 ? 29.376 4.912 -9.424 1.00 47.92 ? 16 MET C SD 1 ATOM 2698 C CE . MET C 1 16 ? 27.619 5.107 -9.725 1.00 46.86 ? 16 MET C CE 1 ATOM 2699 N N . ASP C 1 17 ? 29.784 5.392 -15.337 1.00 33.26 ? 17 ASP C N 1 ATOM 2700 C CA . ASP C 1 17 ? 29.487 6.645 -16.052 1.00 31.49 ? 17 ASP C CA 1 ATOM 2701 C C . ASP C 1 17 ? 29.971 7.905 -15.307 1.00 31.19 ? 17 ASP C C 1 ATOM 2702 O O . ASP C 1 17 ? 29.476 8.999 -15.577 1.00 29.92 ? 17 ASP C O 1 ATOM 2703 C CB . ASP C 1 17 ? 27.986 6.772 -16.359 1.00 30.69 ? 17 ASP C CB 1 ATOM 2704 C CG . ASP C 1 17 ? 27.558 6.021 -17.620 1.00 33.28 ? 17 ASP C CG 1 ATOM 2705 O OD1 . ASP C 1 17 ? 28.408 5.503 -18.393 1.00 32.44 ? 17 ASP C OD1 1 ATOM 2706 O OD2 . ASP C 1 17 ? 26.334 5.962 -17.846 1.00 34.14 ? 17 ASP C OD2 1 ATOM 2707 N N . THR C 1 18 ? 30.918 7.754 -14.375 1.00 29.58 ? 18 THR C N 1 ATOM 2708 C CA . THR C 1 18 ? 31.403 8.894 -13.574 1.00 29.82 ? 18 THR C CA 1 ATOM 2709 C C . THR C 1 18 ? 32.919 8.999 -13.554 1.00 28.21 ? 18 THR C C 1 ATOM 2710 O O . THR C 1 18 ? 33.469 10.055 -13.287 1.00 29.45 ? 18 THR C O 1 ATOM 2711 C CB . THR C 1 18 ? 30.885 8.885 -12.090 1.00 31.38 ? 18 THR C CB 1 ATOM 2712 O OG1 . THR C 1 18 ? 31.549 7.855 -11.330 1.00 32.04 ? 18 THR C OG1 1 ATOM 2713 C CG2 . THR C 1 18 ? 29.369 8.706 -12.024 1.00 30.50 ? 18 THR C CG2 1 ATOM 2714 N N . GLN C 1 19 ? 33.596 7.897 -13.820 1.00 29.10 ? 19 GLN C N 1 ATOM 2715 C CA . GLN C 1 19 ? 35.051 7.885 -13.833 1.00 29.34 ? 19 GLN C CA 1 ATOM 2716 C C . GLN C 1 19 ? 35.507 7.200 -15.110 1.00 27.05 ? 19 GLN C C 1 ATOM 2717 O O . GLN C 1 19 ? 35.100 6.069 -15.403 1.00 25.17 ? 19 GLN C O 1 ATOM 2718 C CB . GLN C 1 19 ? 35.615 7.169 -12.593 1.00 30.25 ? 19 GLN C CB 1 ATOM 2719 C CG . GLN C 1 19 ? 35.423 7.918 -11.273 1.00 32.29 ? 19 GLN C CG 1 ATOM 2720 C CD . GLN C 1 19 ? 35.870 7.104 -10.064 1.00 34.57 ? 19 GLN C CD 1 ATOM 2721 O OE1 . GLN C 1 19 ? 37.000 6.609 -10.014 1.00 36.01 ? 19 GLN C OE1 1 ATOM 2722 N NE2 . GLN C 1 19 ? 34.985 6.975 -9.075 1.00 35.88 ? 19 GLN C NE2 1 ATOM 2723 N N . TYR C 1 20 ? 36.342 7.907 -15.864 1.00 23.91 ? 20 TYR C N 1 ATOM 2724 C CA . TYR C 1 20 ? 36.884 7.420 -17.097 1.00 22.75 ? 20 TYR C CA 1 ATOM 2725 C C . TYR C 1 20 ? 38.394 7.540 -17.003 1.00 25.14 ? 20 TYR C C 1 ATOM 2726 O O . TYR C 1 20 ? 38.950 8.645 -16.968 1.00 27.63 ? 20 TYR C O 1 ATOM 2727 C CB . TYR C 1 20 ? 36.366 8.260 -18.271 1.00 23.57 ? 20 TYR C CB 1 ATOM 2728 C CG . TYR C 1 20 ? 34.891 8.090 -18.602 1.00 24.03 ? 20 TYR C CG 1 ATOM 2729 C CD1 . TYR C 1 20 ? 34.473 7.137 -19.541 1.00 21.88 ? 20 TYR C CD1 1 ATOM 2730 C CD2 . TYR C 1 20 ? 33.918 8.899 -18.003 1.00 23.43 ? 20 TYR C CD2 1 ATOM 2731 C CE1 . TYR C 1 20 ? 33.143 6.985 -19.867 1.00 20.59 ? 20 TYR C CE1 1 ATOM 2732 C CE2 . TYR C 1 20 ? 32.573 8.747 -18.318 1.00 23.24 ? 20 TYR C CE2 1 ATOM 2733 C CZ . TYR C 1 20 ? 32.189 7.780 -19.254 1.00 23.84 ? 20 TYR C CZ 1 ATOM 2734 O OH . TYR C 1 20 ? 30.845 7.616 -19.585 1.00 24.45 ? 20 TYR C OH 1 ATOM 2735 N N . TYR C 1 21 ? 39.074 6.404 -16.969 1.00 25.97 ? 21 TYR C N 1 ATOM 2736 C CA . TYR C 1 21 ? 40.508 6.422 -16.755 1.00 26.37 ? 21 TYR C CA 1 ATOM 2737 C C . TYR C 1 21 ? 41.210 5.425 -17.634 1.00 28.06 ? 21 TYR C C 1 ATOM 2738 O O . TYR C 1 21 ? 40.631 4.406 -18.029 1.00 29.19 ? 21 TYR C O 1 ATOM 2739 C CB . TYR C 1 21 ? 40.836 6.135 -15.290 1.00 27.07 ? 21 TYR C CB 1 ATOM 2740 C CG . TYR C 1 21 ? 40.205 4.876 -14.750 1.00 26.51 ? 21 TYR C CG 1 ATOM 2741 C CD1 . TYR C 1 21 ? 40.902 3.675 -14.737 1.00 23.97 ? 21 TYR C CD1 1 ATOM 2742 C CD2 . TYR C 1 21 ? 38.891 4.889 -14.265 1.00 27.32 ? 21 TYR C CD2 1 ATOM 2743 C CE1 . TYR C 1 21 ? 40.317 2.514 -14.231 1.00 26.55 ? 21 TYR C CE1 1 ATOM 2744 C CE2 . TYR C 1 21 ? 38.296 3.737 -13.762 1.00 27.77 ? 21 TYR C CE2 1 ATOM 2745 C CZ . TYR C 1 21 ? 39.015 2.557 -13.743 1.00 27.59 ? 21 TYR C CZ 1 ATOM 2746 O OH . TYR C 1 21 ? 38.410 1.424 -13.249 1.00 29.03 ? 21 TYR C OH 1 ATOM 2747 N N . GLY C 1 22 ? 42.472 5.724 -17.919 1.00 29.41 ? 22 GLY C N 1 ATOM 2748 C CA . GLY C 1 22 ? 43.330 4.818 -18.650 1.00 31.10 ? 22 GLY C CA 1 ATOM 2749 C C . GLY C 1 22 ? 44.624 4.618 -17.889 1.00 32.98 ? 22 GLY C C 1 ATOM 2750 O O . GLY C 1 22 ? 44.753 5.014 -16.735 1.00 32.37 ? 22 GLY C O 1 ATOM 2751 N N . GLU C 1 23 ? 45.588 4.006 -18.556 1.00 34.59 ? 23 GLU C N 1 ATOM 2752 C CA . GLU C 1 23 ? 46.866 3.722 -17.956 1.00 35.07 ? 23 GLU C CA 1 ATOM 2753 C C . GLU C 1 23 ? 48.019 4.424 -18.667 1.00 35.21 ? 23 GLU C C 1 ATOM 2754 O O . GLU C 1 23 ? 48.054 4.504 -19.904 1.00 34.14 ? 23 GLU C O 1 ATOM 2755 C CB . GLU C 1 23 ? 47.089 2.218 -17.935 1.00 37.31 ? 23 GLU C CB 1 ATOM 2756 C CG . GLU C 1 23 ? 46.094 1.502 -17.043 1.00 39.35 ? 23 GLU C CG 1 ATOM 2757 C CD . GLU C 1 23 ? 46.450 0.066 -16.827 1.00 41.88 ? 23 GLU C CD 1 ATOM 2758 O OE1 . GLU C 1 23 ? 46.687 -0.647 -17.831 1.00 43.14 ? 23 GLU C OE1 1 ATOM 2759 O OE2 . GLU C 1 23 ? 46.485 -0.350 -15.646 1.00 44.61 ? 23 GLU C OE2 1 ATOM 2760 N N . ILE C 1 24 ? 48.932 4.955 -17.852 1.00 33.56 ? 24 ILE C N 1 ATOM 2761 C CA . ILE C 1 24 ? 50.221 5.464 -18.291 1.00 31.94 ? 24 ILE C CA 1 ATOM 2762 C C . ILE C 1 24 ? 51.365 4.760 -17.518 1.00 32.73 ? 24 ILE C C 1 ATOM 2763 O O . ILE C 1 24 ? 51.168 4.254 -16.409 1.00 32.70 ? 24 ILE C O 1 ATOM 2764 C CB . ILE C 1 24 ? 50.311 6.998 -18.085 1.00 32.15 ? 24 ILE C CB 1 ATOM 2765 C CG1 . ILE C 1 24 ? 50.313 7.336 -16.577 1.00 31.52 ? 24 ILE C CG1 1 ATOM 2766 C CG2 . ILE C 1 24 ? 49.190 7.725 -18.891 1.00 29.43 ? 24 ILE C CG2 1 ATOM 2767 C CD1 . ILE C 1 24 ? 50.643 8.788 -16.218 1.00 31.72 ? 24 ILE C CD1 1 ATOM 2768 N N . GLY C 1 25 ? 52.552 4.714 -18.113 1.00 33.67 ? 25 GLY C N 1 ATOM 2769 C CA . GLY C 1 25 ? 53.741 4.247 -17.402 1.00 34.23 ? 25 GLY C CA 1 ATOM 2770 C C . GLY C 1 25 ? 54.573 5.430 -16.944 1.00 34.41 ? 25 GLY C C 1 ATOM 2771 O O . GLY C 1 25 ? 54.679 6.414 -17.662 1.00 34.84 ? 25 GLY C O 1 ATOM 2772 N N . ILE C 1 26 ? 55.124 5.347 -15.736 1.00 34.31 ? 26 ILE C N 1 ATOM 2773 C CA . ILE C 1 26 ? 56.134 6.302 -15.258 1.00 34.82 ? 26 ILE C CA 1 ATOM 2774 C C . ILE C 1 26 ? 57.381 5.531 -14.807 1.00 37.14 ? 26 ILE C C 1 ATOM 2775 O O . ILE C 1 26 ? 57.277 4.580 -14.023 1.00 38.84 ? 26 ILE C O 1 ATOM 2776 C CB . ILE C 1 26 ? 55.632 7.176 -14.081 1.00 34.93 ? 26 ILE C CB 1 ATOM 2777 C CG1 . ILE C 1 26 ? 54.233 7.746 -14.379 1.00 34.94 ? 26 ILE C CG1 1 ATOM 2778 C CG2 . ILE C 1 26 ? 56.649 8.292 -13.767 1.00 34.89 ? 26 ILE C CG2 1 ATOM 2779 C CD1 . ILE C 1 26 ? 53.577 8.476 -13.241 1.00 33.10 ? 26 ILE C CD1 1 ATOM 2780 N N . GLY C 1 27 ? 58.546 5.917 -15.329 1.00 37.30 ? 27 GLY C N 1 ATOM 2781 C CA . GLY C 1 27 ? 59.817 5.342 -14.897 1.00 39.16 ? 27 GLY C CA 1 ATOM 2782 C C . GLY C 1 27 ? 60.398 4.217 -15.738 1.00 41.17 ? 27 GLY C C 1 ATOM 2783 O O . GLY C 1 27 ? 59.742 3.710 -16.650 1.00 40.54 ? 27 GLY C O 1 ATOM 2784 N N . THR C 1 28 ? 61.640 3.843 -15.415 1.00 42.96 ? 28 THR C N 1 ATOM 2785 C CA . THR C 1 28 ? 62.357 2.725 -16.050 1.00 45.09 ? 28 THR C CA 1 ATOM 2786 C C . THR C 1 28 ? 62.772 1.684 -14.990 1.00 46.50 ? 28 THR C C 1 ATOM 2787 O O . THR C 1 28 ? 63.676 1.937 -14.188 1.00 47.40 ? 28 THR C O 1 ATOM 2788 C CB . THR C 1 28 ? 63.606 3.225 -16.824 1.00 44.93 ? 28 THR C CB 1 ATOM 2789 O OG1 . THR C 1 28 ? 63.221 4.262 -17.735 1.00 46.53 ? 28 THR C OG1 1 ATOM 2790 C CG2 . THR C 1 28 ? 64.261 2.099 -17.597 1.00 44.28 ? 28 THR C CG2 1 ATOM 2791 N N . PRO C 1 29 ? 62.106 0.511 -14.974 1.00 47.47 ? 29 PRO C N 1 ATOM 2792 C CA . PRO C 1 29 ? 61.075 0.095 -15.926 1.00 47.39 ? 29 PRO C CA 1 ATOM 2793 C C . PRO C 1 29 ? 59.735 0.714 -15.515 1.00 46.55 ? 29 PRO C C 1 ATOM 2794 O O . PRO C 1 29 ? 59.638 1.245 -14.408 1.00 46.76 ? 29 PRO C O 1 ATOM 2795 C CB . PRO C 1 29 ? 61.067 -1.435 -15.796 1.00 47.54 ? 29 PRO C CB 1 ATOM 2796 C CG . PRO C 1 29 ? 61.651 -1.738 -14.447 1.00 47.76 ? 29 PRO C CG 1 ATOM 2797 C CD . PRO C 1 29 ? 62.301 -0.487 -13.903 1.00 47.99 ? 29 PRO C CD 1 ATOM 2798 N N . PRO C 1 30 ? 58.722 0.679 -16.402 1.00 46.54 ? 30 PRO C N 1 ATOM 2799 C CA . PRO C 1 30 ? 57.496 1.447 -16.130 1.00 44.82 ? 30 PRO C CA 1 ATOM 2800 C C . PRO C 1 30 ? 56.697 0.974 -14.912 1.00 44.22 ? 30 PRO C C 1 ATOM 2801 O O . PRO C 1 30 ? 56.446 -0.228 -14.747 1.00 44.15 ? 30 PRO C O 1 ATOM 2802 C CB . PRO C 1 30 ? 56.670 1.274 -17.411 1.00 44.49 ? 30 PRO C CB 1 ATOM 2803 C CG . PRO C 1 30 ? 57.622 0.755 -18.440 1.00 45.76 ? 30 PRO C CG 1 ATOM 2804 C CD . PRO C 1 30 ? 58.643 -0.035 -17.690 1.00 46.37 ? 30 PRO C CD 1 ATOM 2805 N N . GLN C 1 31 ? 56.331 1.936 -14.067 1.00 42.18 ? 31 GLN C N 1 ATOM 2806 C CA . GLN C 1 31 ? 55.326 1.749 -13.031 1.00 40.26 ? 31 GLN C CA 1 ATOM 2807 C C . GLN C 1 31 ? 53.982 2.242 -13.583 1.00 39.50 ? 31 GLN C C 1 ATOM 2808 O O . GLN C 1 31 ? 53.843 3.423 -13.926 1.00 37.69 ? 31 GLN C O 1 ATOM 2809 C CB . GLN C 1 31 ? 55.721 2.518 -11.761 1.00 39.79 ? 31 GLN C CB 1 ATOM 2810 C CG . GLN C 1 31 ? 56.923 1.915 -11.030 1.00 39.48 ? 31 GLN C CG 1 ATOM 2811 C CD . GLN C 1 31 ? 57.553 2.860 -10.013 1.00 39.56 ? 31 GLN C CD 1 ATOM 2812 O OE1 . GLN C 1 31 ? 56.911 3.271 -9.041 1.00 37.56 ? 31 GLN C OE1 1 ATOM 2813 N NE2 . GLN C 1 31 ? 58.830 3.190 -10.224 1.00 39.14 ? 31 GLN C NE2 1 ATOM 2814 N N . THR C 1 32 ? 53.011 1.330 -13.693 1.00 38.62 ? 32 THR C N 1 ATOM 2815 C CA . THR C 1 32 ? 51.705 1.641 -14.289 1.00 37.45 ? 32 THR C CA 1 ATOM 2816 C C . THR C 1 32 ? 50.749 2.349 -13.320 1.00 36.63 ? 32 THR C C 1 ATOM 2817 O O . THR C 1 32 ? 50.599 1.946 -12.174 1.00 36.16 ? 32 THR C O 1 ATOM 2818 C CB . THR C 1 32 ? 51.001 0.381 -14.876 1.00 38.63 ? 32 THR C CB 1 ATOM 2819 O OG1 . THR C 1 32 ? 50.673 -0.522 -13.818 1.00 40.34 ? 32 THR C OG1 1 ATOM 2820 C CG2 . THR C 1 32 ? 51.885 -0.340 -15.900 1.00 36.87 ? 32 THR C CG2 1 ATOM 2821 N N . PHE C 1 33 ? 50.106 3.412 -13.793 1.00 36.35 ? 33 PHE C N 1 ATOM 2822 C CA . PHE C 1 33 ? 49.074 4.096 -13.018 1.00 36.84 ? 33 PHE C CA 1 ATOM 2823 C C . PHE C 1 33 ? 47.788 4.229 -13.821 1.00 36.00 ? 33 PHE C C 1 ATOM 2824 O O . PHE C 1 33 ? 47.828 4.533 -15.009 1.00 37.62 ? 33 PHE C O 1 ATOM 2825 C CB . PHE C 1 33 ? 49.550 5.488 -12.599 1.00 36.21 ? 33 PHE C CB 1 ATOM 2826 C CG . PHE C 1 33 ? 50.690 5.467 -11.637 1.00 35.92 ? 33 PHE C CG 1 ATOM 2827 C CD1 . PHE C 1 33 ? 50.473 5.706 -10.290 1.00 34.83 ? 33 PHE C CD1 1 ATOM 2828 C CD2 . PHE C 1 33 ? 51.992 5.203 -12.081 1.00 36.51 ? 33 PHE C CD2 1 ATOM 2829 C CE1 . PHE C 1 33 ? 51.526 5.678 -9.391 1.00 35.21 ? 33 PHE C CE1 1 ATOM 2830 C CE2 . PHE C 1 33 ? 53.051 5.176 -11.193 1.00 35.48 ? 33 PHE C CE2 1 ATOM 2831 C CZ . PHE C 1 33 ? 52.813 5.411 -9.841 1.00 36.37 ? 33 PHE C CZ 1 ATOM 2832 N N . LYS C 1 34 ? 46.654 3.986 -13.177 1.00 34.34 ? 34 LYS C N 1 ATOM 2833 C CA . LYS C 1 34 ? 45.370 4.377 -13.752 1.00 32.63 ? 34 LYS C CA 1 ATOM 2834 C C . LYS C 1 34 ? 45.204 5.877 -13.541 1.00 30.35 ? 34 LYS C C 1 ATOM 2835 O O . LYS C 1 34 ? 45.421 6.379 -12.433 1.00 27.87 ? 34 LYS C O 1 ATOM 2836 C CB . LYS C 1 34 ? 44.215 3.640 -13.100 1.00 32.95 ? 34 LYS C CB 1 ATOM 2837 C CG . LYS C 1 34 ? 44.403 2.160 -12.981 1.00 34.22 ? 34 LYS C CG 1 ATOM 2838 C CD . LYS C 1 34 ? 43.346 1.608 -12.061 1.00 35.96 ? 34 LYS C CD 1 ATOM 2839 C CE . LYS C 1 34 ? 43.701 0.236 -11.593 1.00 37.58 ? 34 LYS C CE 1 ATOM 2840 N NZ . LYS C 1 34 ? 42.788 -0.144 -10.488 1.00 41.06 ? 34 LYS C NZ 1 ATOM 2841 N N . VAL C 1 35 ? 44.855 6.592 -14.611 1.00 28.70 ? 35 VAL C N 1 ATOM 2842 C CA . VAL C 1 35 ? 44.754 8.049 -14.552 1.00 26.53 ? 35 VAL C CA 1 ATOM 2843 C C . VAL C 1 35 ? 43.544 8.590 -15.319 1.00 26.90 ? 35 VAL C C 1 ATOM 2844 O O . VAL C 1 35 ? 43.116 8.013 -16.321 1.00 26.16 ? 35 VAL C O 1 ATOM 2845 C CB . VAL C 1 35 ? 46.061 8.761 -15.062 1.00 25.14 ? 35 VAL C CB 1 ATOM 2846 C CG1 . VAL C 1 35 ? 47.253 8.456 -14.166 1.00 24.77 ? 35 VAL C CG1 1 ATOM 2847 C CG2 . VAL C 1 35 ? 46.371 8.428 -16.524 1.00 23.93 ? 35 VAL C CG2 1 ATOM 2848 N N . VAL C 1 36 ? 43.008 9.706 -14.837 1.00 26.03 ? 36 VAL C N 1 ATOM 2849 C CA . VAL C 1 36 ? 42.026 10.477 -15.585 1.00 26.68 ? 36 VAL C CA 1 ATOM 2850 C C . VAL C 1 36 ? 42.763 11.499 -16.439 1.00 27.69 ? 36 VAL C C 1 ATOM 2851 O O . VAL C 1 36 ? 43.760 12.096 -15.998 1.00 27.81 ? 36 VAL C O 1 ATOM 2852 C CB . VAL C 1 36 ? 41.017 11.203 -14.647 1.00 26.73 ? 36 VAL C CB 1 ATOM 2853 C CG1 . VAL C 1 36 ? 40.187 12.207 -15.426 1.00 26.11 ? 36 VAL C CG1 1 ATOM 2854 C CG2 . VAL C 1 36 ? 40.123 10.194 -13.944 1.00 25.65 ? 36 VAL C CG2 1 ATOM 2855 N N . PHE C 1 37 ? 42.279 11.686 -17.665 1.00 27.95 ? 37 PHE C N 1 ATOM 2856 C CA . PHE C 1 37 ? 42.811 12.716 -18.544 1.00 28.17 ? 37 PHE C CA 1 ATOM 2857 C C . PHE C 1 37 ? 41.901 13.938 -18.486 1.00 28.62 ? 37 PHE C C 1 ATOM 2858 O O . PHE C 1 37 ? 40.760 13.903 -18.933 1.00 29.50 ? 37 PHE C O 1 ATOM 2859 C CB . PHE C 1 37 ? 43.001 12.175 -19.956 1.00 27.81 ? 37 PHE C CB 1 ATOM 2860 C CG . PHE C 1 37 ? 44.014 11.050 -20.045 1.00 28.04 ? 37 PHE C CG 1 ATOM 2861 C CD1 . PHE C 1 37 ? 43.672 9.746 -19.687 1.00 27.96 ? 37 PHE C CD1 1 ATOM 2862 C CD2 . PHE C 1 37 ? 45.308 11.293 -20.494 1.00 28.47 ? 37 PHE C CD2 1 ATOM 2863 C CE1 . PHE C 1 37 ? 44.605 8.705 -19.772 1.00 27.23 ? 37 PHE C CE1 1 ATOM 2864 C CE2 . PHE C 1 37 ? 46.254 10.243 -20.586 1.00 26.81 ? 37 PHE C CE2 1 ATOM 2865 C CZ . PHE C 1 37 ? 45.898 8.965 -20.218 1.00 26.41 ? 37 PHE C CZ 1 ATOM 2866 N N . ASP C 1 38 ? 42.425 15.018 -17.920 1.00 29.98 ? 38 ASP C N 1 ATOM 2867 C CA . ASP C 1 38 ? 41.601 16.105 -17.406 1.00 30.79 ? 38 ASP C CA 1 ATOM 2868 C C . ASP C 1 38 ? 41.873 17.448 -18.080 1.00 29.66 ? 38 ASP C C 1 ATOM 2869 O O . ASP C 1 38 ? 42.934 18.050 -17.884 1.00 29.93 ? 38 ASP C O 1 ATOM 2870 C CB . ASP C 1 38 ? 41.824 16.212 -15.891 1.00 32.86 ? 38 ASP C CB 1 ATOM 2871 C CG . ASP C 1 38 ? 40.965 17.271 -15.247 1.00 35.24 ? 38 ASP C CG 1 ATOM 2872 O OD1 . ASP C 1 38 ? 39.889 17.594 -15.777 1.00 37.55 ? 38 ASP C OD1 1 ATOM 2873 O OD2 . ASP C 1 38 ? 41.369 17.791 -14.201 1.00 37.74 ? 38 ASP C OD2 1 ATOM 2874 N N . THR C 1 39 ? 40.908 17.929 -18.855 1.00 29.14 ? 39 THR C N 1 ATOM 2875 C CA . THR C 1 39 ? 41.092 19.183 -19.593 1.00 30.68 ? 39 THR C CA 1 ATOM 2876 C C . THR C 1 39 ? 40.858 20.387 -18.699 1.00 32.64 ? 39 THR C C 1 ATOM 2877 O O . THR C 1 39 ? 41.093 21.527 -19.112 1.00 34.74 ? 39 THR C O 1 ATOM 2878 C CB . THR C 1 39 ? 40.183 19.285 -20.852 1.00 29.83 ? 39 THR C CB 1 ATOM 2879 O OG1 . THR C 1 39 ? 38.824 19.002 -20.491 1.00 30.35 ? 39 THR C OG1 1 ATOM 2880 C CG2 . THR C 1 39 ? 40.647 18.314 -21.941 1.00 28.15 ? 39 THR C CG2 1 ATOM 2881 N N . GLY C 1 40 ? 40.391 20.125 -17.477 1.00 33.45 ? 40 GLY C N 1 ATOM 2882 C CA . GLY C 1 40 ? 40.179 21.166 -16.480 1.00 32.69 ? 40 GLY C CA 1 ATOM 2883 C C . GLY C 1 40 ? 41.343 21.363 -15.530 1.00 32.38 ? 40 GLY C C 1 ATOM 2884 O O . GLY C 1 40 ? 41.198 22.047 -14.518 1.00 32.17 ? 40 GLY C O 1 ATOM 2885 N N . SER C 1 41 ? 42.483 20.743 -15.846 1.00 31.37 ? 41 SER C N 1 ATOM 2886 C CA . SER C 1 41 ? 43.739 20.924 -15.101 1.00 31.77 ? 41 SER C CA 1 ATOM 2887 C C . SER C 1 41 ? 44.963 20.670 -16.000 1.00 32.56 ? 41 SER C C 1 ATOM 2888 O O . SER C 1 41 ? 44.812 20.143 -17.104 1.00 32.87 ? 41 SER C O 1 ATOM 2889 C CB . SER C 1 41 ? 43.767 20.042 -13.852 1.00 31.86 ? 41 SER C CB 1 ATOM 2890 O OG . SER C 1 41 ? 43.703 18.659 -14.166 1.00 31.86 ? 41 SER C OG 1 ATOM 2891 N N . SER C 1 42 ? 46.163 21.038 -15.545 1.00 31.53 ? 42 SER C N 1 ATOM 2892 C CA . SER C 1 42 ? 47.321 21.075 -16.454 1.00 32.10 ? 42 SER C CA 1 ATOM 2893 C C . SER C 1 42 ? 48.558 20.306 -15.996 1.00 33.38 ? 42 SER C C 1 ATOM 2894 O O . SER C 1 42 ? 49.599 20.350 -16.664 1.00 32.04 ? 42 SER C O 1 ATOM 2895 C CB . SER C 1 42 ? 47.700 22.523 -16.765 1.00 31.64 ? 42 SER C CB 1 ATOM 2896 O OG . SER C 1 42 ? 46.561 23.270 -17.178 1.00 31.72 ? 42 SER C OG 1 ATOM 2897 N N . ASN C 1 43 ? 48.433 19.601 -14.869 1.00 33.20 ? 43 ASN C N 1 ATOM 2898 C CA . ASN C 1 43 ? 49.554 18.920 -14.235 1.00 33.41 ? 43 ASN C CA 1 ATOM 2899 C C . ASN C 1 43 ? 49.345 17.419 -14.233 1.00 33.57 ? 43 ASN C C 1 ATOM 2900 O O . ASN C 1 43 ? 48.209 16.940 -14.253 1.00 32.67 ? 43 ASN C O 1 ATOM 2901 C CB . ASN C 1 43 ? 49.711 19.383 -12.775 1.00 35.02 ? 43 ASN C CB 1 ATOM 2902 C CG . ASN C 1 43 ? 50.025 20.865 -12.643 1.00 34.70 ? 43 ASN C CG 1 ATOM 2903 O OD1 . ASN C 1 43 ? 49.130 21.677 -12.460 1.00 36.42 ? 43 ASN C OD1 1 ATOM 2904 N ND2 . ASN C 1 43 ? 51.301 21.216 -12.729 1.00 34.89 ? 43 ASN C ND2 1 ATOM 2905 N N . VAL C 1 44 ? 50.449 16.679 -14.213 1.00 33.57 ? 44 VAL C N 1 ATOM 2906 C CA . VAL C 1 44 ? 50.404 15.257 -13.928 1.00 33.77 ? 44 VAL C CA 1 ATOM 2907 C C . VAL C 1 44 ? 50.632 15.067 -12.428 1.00 35.25 ? 44 VAL C C 1 ATOM 2908 O O . VAL C 1 44 ? 51.671 15.476 -11.906 1.00 36.20 ? 44 VAL C O 1 ATOM 2909 C CB . VAL C 1 44 ? 51.492 14.479 -14.684 1.00 32.79 ? 44 VAL C CB 1 ATOM 2910 C CG1 . VAL C 1 44 ? 51.403 12.988 -14.355 1.00 30.60 ? 44 VAL C CG1 1 ATOM 2911 C CG2 . VAL C 1 44 ? 51.402 14.716 -16.192 1.00 33.01 ? 44 VAL C CG2 1 ATOM 2912 N N . TRP C 1 45 ? 49.668 14.461 -11.740 1.00 36.01 ? 45 TRP C N 1 ATOM 2913 C CA . TRP C 1 45 ? 49.868 14.061 -10.343 1.00 37.65 ? 45 TRP C CA 1 ATOM 2914 C C . TRP C 1 45 ? 49.705 12.556 -10.186 1.00 38.30 ? 45 TRP C C 1 ATOM 2915 O O . TRP C 1 45 ? 48.755 11.968 -10.710 1.00 39.06 ? 45 TRP C O 1 ATOM 2916 C CB . TRP C 1 45 ? 48.849 14.704 -9.407 1.00 39.39 ? 45 TRP C CB 1 ATOM 2917 C CG . TRP C 1 45 ? 48.740 16.184 -9.425 1.00 39.82 ? 45 TRP C CG 1 ATOM 2918 C CD1 . TRP C 1 45 ? 47.920 16.931 -10.218 1.00 40.15 ? 45 TRP C CD1 1 ATOM 2919 C CD2 . TRP C 1 45 ? 49.421 17.106 -8.569 1.00 40.13 ? 45 TRP C CD2 1 ATOM 2920 N NE1 . TRP C 1 45 ? 48.058 18.262 -9.923 1.00 40.35 ? 45 TRP C NE1 1 ATOM 2921 C CE2 . TRP C 1 45 ? 48.978 18.400 -8.917 1.00 40.89 ? 45 TRP C CE2 1 ATOM 2922 C CE3 . TRP C 1 45 ? 50.378 16.966 -7.552 1.00 40.74 ? 45 TRP C CE3 1 ATOM 2923 C CZ2 . TRP C 1 45 ? 49.460 19.557 -8.283 1.00 41.02 ? 45 TRP C CZ2 1 ATOM 2924 C CZ3 . TRP C 1 45 ? 50.855 18.113 -6.914 1.00 40.46 ? 45 TRP C CZ3 1 ATOM 2925 C CH2 . TRP C 1 45 ? 50.395 19.392 -7.287 1.00 40.96 ? 45 TRP C CH2 1 ATOM 2926 N N . VAL C 1 46 ? 50.629 11.942 -9.458 1.00 37.64 ? 46 VAL C N 1 ATOM 2927 C CA . VAL C 1 46 ? 50.424 10.604 -8.916 1.00 37.18 ? 46 VAL C CA 1 ATOM 2928 C C . VAL C 1 46 ? 50.850 10.587 -7.442 1.00 38.21 ? 46 VAL C C 1 ATOM 2929 O O . VAL C 1 46 ? 51.680 11.410 -7.040 1.00 37.59 ? 46 VAL C O 1 ATOM 2930 C CB . VAL C 1 46 ? 51.145 9.500 -9.728 1.00 36.48 ? 46 VAL C CB 1 ATOM 2931 C CG1 . VAL C 1 46 ? 50.611 9.447 -11.165 1.00 37.23 ? 46 VAL C CG1 1 ATOM 2932 C CG2 . VAL C 1 46 ? 52.653 9.678 -9.702 1.00 36.45 ? 46 VAL C CG2 1 ATOM 2933 N N . PRO C 1 47 ? 50.274 9.666 -6.629 1.00 37.50 ? 47 PRO C N 1 ATOM 2934 C CA . PRO C 1 47 ? 50.686 9.565 -5.231 1.00 36.01 ? 47 PRO C CA 1 ATOM 2935 C C . PRO C 1 47 ? 52.150 9.145 -5.092 1.00 35.27 ? 47 PRO C C 1 ATOM 2936 O O . PRO C 1 47 ? 52.647 8.324 -5.869 1.00 34.00 ? 47 PRO C O 1 ATOM 2937 C CB . PRO C 1 47 ? 49.767 8.474 -4.667 1.00 36.31 ? 47 PRO C CB 1 ATOM 2938 C CG . PRO C 1 47 ? 48.615 8.387 -5.622 1.00 36.20 ? 47 PRO C CG 1 ATOM 2939 C CD . PRO C 1 47 ? 49.230 8.674 -6.953 1.00 36.93 ? 47 PRO C CD 1 ATOM 2940 N N . SER C 1 48 ? 52.828 9.719 -4.105 1.00 36.46 ? 48 SER C N 1 ATOM 2941 C CA . SER C 1 48 ? 54.214 9.382 -3.824 1.00 39.08 ? 48 SER C CA 1 ATOM 2942 C C . SER C 1 48 ? 54.316 8.196 -2.872 1.00 41.11 ? 48 SER C C 1 ATOM 2943 O O . SER C 1 48 ? 53.431 7.980 -2.041 1.00 41.38 ? 48 SER C O 1 ATOM 2944 C CB . SER C 1 48 ? 54.929 10.585 -3.218 1.00 38.52 ? 48 SER C CB 1 ATOM 2945 O OG . SER C 1 48 ? 56.311 10.320 -3.093 1.00 38.12 ? 48 SER C OG 1 ATOM 2946 N N . SER C 1 49 ? 55.399 7.431 -2.993 1.00 44.24 ? 49 SER C N 1 ATOM 2947 C CA . SER C 1 49 ? 55.726 6.408 -1.990 1.00 47.06 ? 49 SER C CA 1 ATOM 2948 C C . SER C 1 49 ? 56.118 7.060 -0.667 1.00 49.01 ? 49 SER C C 1 ATOM 2949 O O . SER C 1 49 ? 56.233 6.382 0.351 1.00 50.45 ? 49 SER C O 1 ATOM 2950 C CB . SER C 1 49 ? 56.852 5.494 -2.471 1.00 46.78 ? 49 SER C CB 1 ATOM 2951 O OG . SER C 1 49 ? 58.062 6.211 -2.623 1.00 48.37 ? 49 SER C OG 1 ATOM 2952 N N . LYS C 1 50 ? 56.314 8.376 -0.704 1.00 51.00 ? 50 LYS C N 1 ATOM 2953 C CA . LYS C 1 50 ? 56.634 9.190 0.467 1.00 54.35 ? 50 LYS C CA 1 ATOM 2954 C C . LYS C 1 50 ? 55.382 9.856 1.062 1.00 56.56 ? 50 LYS C C 1 ATOM 2955 O O . LYS C 1 50 ? 55.475 10.796 1.854 1.00 57.37 ? 50 LYS C O 1 ATOM 2956 C CB . LYS C 1 50 ? 57.694 10.237 0.091 1.00 54.97 ? 50 LYS C CB 1 ATOM 2957 C CG . LYS C 1 50 ? 59.095 9.653 -0.025 1.00 56.42 ? 50 LYS C CG 1 ATOM 2958 C CD . LYS C 1 50 ? 59.745 9.984 -1.352 1.00 57.90 ? 50 LYS C CD 1 ATOM 2959 C CE . LYS C 1 50 ? 60.828 8.951 -1.699 1.00 59.28 ? 50 LYS C CE 1 ATOM 2960 N NZ . LYS C 1 50 ? 61.235 8.991 -3.144 1.00 59.26 ? 50 LYS C NZ 1 ATOM 2961 N N . CYS C 1 51 ? 54.212 9.372 0.659 1.00 59.03 ? 51 CYS C N 1 ATOM 2962 C CA . CYS C 1 51 ? 52.960 9.744 1.301 1.00 61.28 ? 51 CYS C CA 1 ATOM 2963 C C . CYS C 1 51 ? 52.770 8.803 2.489 1.00 63.53 ? 51 CYS C C 1 ATOM 2964 O O . CYS C 1 51 ? 52.878 7.580 2.341 1.00 64.81 ? 51 CYS C O 1 ATOM 2965 C CB . CYS C 1 51 ? 51.796 9.620 0.316 1.00 60.10 ? 51 CYS C CB 1 ATOM 2966 S SG . CYS C 1 51 ? 50.226 10.313 0.893 1.00 59.89 ? 51 CYS C SG 1 ATOM 2967 N N . SER C 1 52 ? 52.518 9.371 3.665 1.00 65.53 ? 52 SER C N 1 ATOM 2968 C CA . SER C 1 52 ? 52.352 8.584 4.890 1.00 67.89 ? 52 SER C CA 1 ATOM 2969 C C . SER C 1 52 ? 51.173 7.633 4.767 1.00 69.52 ? 52 SER C C 1 ATOM 2970 O O . SER C 1 52 ? 50.181 7.952 4.102 1.00 70.16 ? 52 SER C O 1 ATOM 2971 C CB . SER C 1 52 ? 52.106 9.491 6.101 1.00 68.10 ? 52 SER C CB 1 ATOM 2972 O OG . SER C 1 52 ? 52.869 10.685 6.038 1.00 68.72 ? 52 SER C OG 1 ATOM 2973 N N . ARG C 1 53 ? 51.281 6.476 5.420 1.00 70.60 ? 53 ARG C N 1 ATOM 2974 C CA . ARG C 1 53 ? 50.137 5.578 5.599 1.00 72.08 ? 53 ARG C CA 1 ATOM 2975 C C . ARG C 1 53 ? 49.022 6.292 6.373 1.00 70.15 ? 53 ARG C C 1 ATOM 2976 O O . ARG C 1 53 ? 47.910 5.782 6.500 1.00 69.47 ? 53 ARG C O 1 ATOM 2977 C CB . ARG C 1 53 ? 50.556 4.274 6.304 1.00 73.24 ? 53 ARG C CB 1 ATOM 2978 C CG . ARG C 1 53 ? 51.303 4.457 7.629 1.00 74.41 ? 53 ARG C CG 1 ATOM 2979 C CD . ARG C 1 53 ? 51.715 3.121 8.250 1.00 75.14 ? 53 ARG C CD 1 ATOM 2980 N NE . ARG C 1 53 ? 50.853 2.724 9.367 1.00 77.13 ? 53 ARG C NE 1 ATOM 2981 C CZ . ARG C 1 53 ? 49.732 2.013 9.253 1.00 78.16 ? 53 ARG C CZ 1 ATOM 2982 N NH1 . ARG C 1 53 ? 49.302 1.601 8.065 1.00 78.45 ? 53 ARG C NH1 1 ATOM 2983 N NH2 . ARG C 1 53 ? 49.031 1.711 10.338 1.00 78.76 ? 53 ARG C NH2 1 ATOM 2984 N N . LEU C 1 54 ? 49.334 7.490 6.858 1.00 68.95 ? 54 LEU C N 1 ATOM 2985 C CA . LEU C 1 54 ? 48.407 8.282 7.647 1.00 69.38 ? 54 LEU C CA 1 ATOM 2986 C C . LEU C 1 54 ? 47.337 8.969 6.792 1.00 67.69 ? 54 LEU C C 1 ATOM 2987 O O . LEU C 1 54 ? 46.285 9.357 7.310 1.00 67.91 ? 54 LEU C O 1 ATOM 2988 C CB . LEU C 1 54 ? 49.180 9.304 8.487 1.00 70.81 ? 54 LEU C CB 1 ATOM 2989 C CG . LEU C 1 54 ? 48.902 9.375 9.998 1.00 71.78 ? 54 LEU C CG 1 ATOM 2990 C CD1 . LEU C 1 54 ? 49.177 8.032 10.691 1.00 71.91 ? 54 LEU C CD1 1 ATOM 2991 C CD2 . LEU C 1 54 ? 49.742 10.483 10.639 1.00 71.19 ? 54 LEU C CD2 1 ATOM 2992 N N . TYR C 1 55 ? 47.607 9.120 5.493 1.00 65.44 ? 55 TYR C N 1 ATOM 2993 C CA . TYR C 1 55 ? 46.600 9.611 4.539 1.00 62.82 ? 55 TYR C CA 1 ATOM 2994 C C . TYR C 1 55 ? 45.878 8.434 3.879 1.00 62.54 ? 55 TYR C C 1 ATOM 2995 O O . TYR C 1 55 ? 46.509 7.561 3.270 1.00 62.58 ? 55 TYR C O 1 ATOM 2996 C CB . TYR C 1 55 ? 47.224 10.538 3.494 1.00 60.70 ? 55 TYR C CB 1 ATOM 2997 C CG . TYR C 1 55 ? 47.735 11.845 4.059 1.00 59.54 ? 55 TYR C CG 1 ATOM 2998 C CD1 . TYR C 1 55 ? 46.867 12.904 4.307 1.00 59.77 ? 55 TYR C CD1 1 ATOM 2999 C CD2 . TYR C 1 55 ? 49.086 12.022 4.346 1.00 59.25 ? 55 TYR C CD2 1 ATOM 3000 C CE1 . TYR C 1 55 ? 47.330 14.111 4.828 1.00 59.84 ? 55 TYR C CE1 1 ATOM 3001 C CE2 . TYR C 1 55 ? 49.563 13.221 4.869 1.00 59.13 ? 55 TYR C CE2 1 ATOM 3002 C CZ . TYR C 1 55 ? 48.678 14.261 5.109 1.00 59.89 ? 55 TYR C CZ 1 ATOM 3003 O OH . TYR C 1 55 ? 49.134 15.456 5.622 1.00 59.67 ? 55 TYR C OH 1 ATOM 3004 N N . THR C 1 56 ? 44.555 8.410 4.015 1.00 62.43 ? 56 THR C N 1 ATOM 3005 C CA . THR C 1 56 ? 43.753 7.247 3.606 1.00 62.43 ? 56 THR C CA 1 ATOM 3006 C C . THR C 1 56 ? 43.755 7.031 2.091 1.00 60.41 ? 56 THR C C 1 ATOM 3007 O O . THR C 1 56 ? 43.710 5.896 1.616 1.00 59.55 ? 56 THR C O 1 ATOM 3008 C CB . THR C 1 56 ? 42.280 7.330 4.106 1.00 63.07 ? 56 THR C CB 1 ATOM 3009 O OG1 . THR C 1 56 ? 42.121 8.425 5.019 1.00 63.98 ? 56 THR C OG1 1 ATOM 3010 C CG2 . THR C 1 56 ? 41.882 6.030 4.787 1.00 62.39 ? 56 THR C CG2 1 ATOM 3011 N N . ALA C 1 57 ? 43.811 8.129 1.345 1.00 59.11 ? 57 ALA C N 1 ATOM 3012 C CA . ALA C 1 57 ? 43.828 8.076 -0.110 1.00 58.40 ? 57 ALA C CA 1 ATOM 3013 C C . ALA C 1 57 ? 45.144 7.517 -0.652 1.00 57.38 ? 57 ALA C C 1 ATOM 3014 O O . ALA C 1 57 ? 45.225 7.138 -1.818 1.00 57.40 ? 57 ALA C O 1 ATOM 3015 C CB . ALA C 1 57 ? 43.548 9.448 -0.684 1.00 58.07 ? 57 ALA C CB 1 ATOM 3016 N N . CYS C 1 58 ? 46.166 7.464 0.200 1.00 56.77 ? 58 CYS C N 1 ATOM 3017 C CA . CYS C 1 58 ? 47.480 6.960 -0.190 1.00 56.59 ? 58 CYS C CA 1 ATOM 3018 C C . CYS C 1 58 ? 47.675 5.465 0.071 1.00 55.95 ? 58 CYS C C 1 ATOM 3019 O O . CYS C 1 58 ? 48.343 4.792 -0.713 1.00 56.71 ? 58 CYS C O 1 ATOM 3020 C CB . CYS C 1 58 ? 48.601 7.778 0.465 1.00 57.19 ? 58 CYS C CB 1 ATOM 3021 S SG . CYS C 1 58 ? 48.843 9.417 -0.292 1.00 58.21 ? 58 CYS C SG 1 ATOM 3022 N N . VAL C 1 59 ? 47.094 4.944 1.152 1.00 54.97 ? 59 VAL C N 1 ATOM 3023 C CA . VAL C 1 59 ? 47.263 3.524 1.501 1.00 54.52 ? 59 VAL C CA 1 ATOM 3024 C C . VAL C 1 59 ? 46.643 2.587 0.453 1.00 54.25 ? 59 VAL C C 1 ATOM 3025 O O . VAL C 1 59 ? 47.145 1.476 0.220 1.00 52.99 ? 59 VAL C O 1 ATOM 3026 C CB . VAL C 1 59 ? 46.733 3.185 2.934 1.00 54.98 ? 59 VAL C CB 1 ATOM 3027 C CG1 . VAL C 1 59 ? 45.249 3.490 3.066 1.00 55.46 ? 59 VAL C CG1 1 ATOM 3028 C CG2 . VAL C 1 59 ? 47.009 1.723 3.300 1.00 54.31 ? 59 VAL C CG2 1 ATOM 3029 N N . TYR C 1 60 ? 45.577 3.050 -0.199 1.00 53.45 ? 60 TYR C N 1 ATOM 3030 C CA . TYR C 1 60 ? 44.820 2.182 -1.098 1.00 52.83 ? 60 TYR C CA 1 ATOM 3031 C C . TYR C 1 60 ? 45.079 2.375 -2.605 1.00 51.81 ? 60 TYR C C 1 ATOM 3032 O O . TYR C 1 60 ? 44.600 1.586 -3.419 1.00 52.83 ? 60 TYR C O 1 ATOM 3033 C CB . TYR C 1 60 ? 43.323 2.222 -0.744 1.00 53.51 ? 60 TYR C CB 1 ATOM 3034 C CG . TYR C 1 60 ? 43.015 1.679 0.644 1.00 53.22 ? 60 TYR C CG 1 ATOM 3035 C CD1 . TYR C 1 60 ? 42.264 2.416 1.549 1.00 53.87 ? 60 TYR C CD1 1 ATOM 3036 C CD2 . TYR C 1 60 ? 43.493 0.432 1.052 1.00 53.56 ? 60 TYR C CD2 1 ATOM 3037 C CE1 . TYR C 1 60 ? 41.986 1.927 2.826 1.00 54.65 ? 60 TYR C CE1 1 ATOM 3038 C CE2 . TYR C 1 60 ? 43.224 -0.067 2.323 1.00 53.69 ? 60 TYR C CE2 1 ATOM 3039 C CZ . TYR C 1 60 ? 42.469 0.682 3.207 1.00 54.36 ? 60 TYR C CZ 1 ATOM 3040 O OH . TYR C 1 60 ? 42.194 0.188 4.474 1.00 53.91 ? 60 TYR C OH 1 ATOM 3041 N N . HIS C 1 61 ? 45.846 3.403 -2.968 1.00 49.36 ? 61 HIS C N 1 ATOM 3042 C CA . HIS C 1 61 ? 46.197 3.643 -4.371 1.00 47.15 ? 61 HIS C CA 1 ATOM 3043 C C . HIS C 1 61 ? 47.638 3.279 -4.656 1.00 46.90 ? 61 HIS C C 1 ATOM 3044 O O . HIS C 1 61 ? 48.447 3.195 -3.733 1.00 46.28 ? 61 HIS C O 1 ATOM 3045 C CB . HIS C 1 61 ? 45.935 5.098 -4.767 1.00 45.99 ? 61 HIS C CB 1 ATOM 3046 C CG . HIS C 1 61 ? 44.484 5.414 -4.931 1.00 44.93 ? 61 HIS C CG 1 ATOM 3047 N ND1 . HIS C 1 61 ? 43.822 6.318 -4.129 1.00 43.71 ? 61 HIS C ND1 1 ATOM 3048 C CD2 . HIS C 1 61 ? 43.557 4.913 -5.780 1.00 43.83 ? 61 HIS C CD2 1 ATOM 3049 C CE1 . HIS C 1 61 ? 42.551 6.365 -4.480 1.00 43.88 ? 61 HIS C CE1 1 ATOM 3050 N NE2 . HIS C 1 61 ? 42.366 5.530 -5.487 1.00 44.69 ? 61 HIS C NE2 1 ATOM 3051 N N . LYS C 1 62 ? 47.955 3.055 -5.934 1.00 46.55 ? 62 LYS C N 1 ATOM 3052 C CA . LYS C 1 62 ? 49.338 2.794 -6.317 1.00 46.47 ? 62 LYS C CA 1 ATOM 3053 C C . LYS C 1 62 ? 50.212 4.022 -6.073 1.00 44.29 ? 62 LYS C C 1 ATOM 3054 O O . LYS C 1 62 ? 49.795 5.166 -6.298 1.00 43.25 ? 62 LYS C O 1 ATOM 3055 C CB . LYS C 1 62 ? 49.472 2.300 -7.761 1.00 47.45 ? 62 LYS C CB 1 ATOM 3056 C CG . LYS C 1 62 ? 50.764 1.504 -7.947 1.00 48.71 ? 62 LYS C CG 1 ATOM 3057 C CD . LYS C 1 62 ? 50.979 0.962 -9.347 1.00 48.52 ? 62 LYS C CD 1 ATOM 3058 C CE . LYS C 1 62 ? 52.289 0.150 -9.423 1.00 49.90 ? 62 LYS C CE 1 ATOM 3059 N NZ . LYS C 1 62 ? 53.532 0.902 -8.971 1.00 51.09 ? 62 LYS C NZ 1 ATOM 3060 N N . LEU C 1 63 ? 51.419 3.765 -5.588 1.00 42.98 ? 63 LEU C N 1 ATOM 3061 C CA . LEU C 1 63 ? 52.345 4.821 -5.225 1.00 42.20 ? 63 LEU C CA 1 ATOM 3062 C C . LEU C 1 63 ? 53.570 4.760 -6.116 1.00 42.36 ? 63 LEU C C 1 ATOM 3063 O O . LEU C 1 63 ? 54.049 3.675 -6.461 1.00 42.18 ? 63 LEU C O 1 ATOM 3064 C CB . LEU C 1 63 ? 52.760 4.693 -3.758 1.00 42.00 ? 63 LEU C CB 1 ATOM 3065 C CG . LEU C 1 63 ? 51.696 4.590 -2.653 1.00 41.60 ? 63 LEU C CG 1 ATOM 3066 C CD1 . LEU C 1 63 ? 52.368 4.464 -1.284 1.00 40.67 ? 63 LEU C CD1 1 ATOM 3067 C CD2 . LEU C 1 63 ? 50.734 5.768 -2.664 1.00 40.75 ? 63 LEU C CD2 1 ATOM 3068 N N . PHE C 1 64 ? 54.073 5.930 -6.492 1.00 41.68 ? 64 PHE C N 1 ATOM 3069 C CA . PHE C 1 64 ? 55.304 6.003 -7.269 1.00 41.48 ? 64 PHE C CA 1 ATOM 3070 C C . PHE C 1 64 ? 56.564 5.830 -6.403 1.00 41.86 ? 64 PHE C C 1 ATOM 3071 O O . PHE C 1 64 ? 56.848 6.661 -5.531 1.00 42.18 ? 64 PHE C O 1 ATOM 3072 C CB . PHE C 1 64 ? 55.368 7.315 -8.066 1.00 39.34 ? 64 PHE C CB 1 ATOM 3073 C CG . PHE C 1 64 ? 56.616 7.460 -8.867 1.00 38.22 ? 64 PHE C CG 1 ATOM 3074 C CD1 . PHE C 1 64 ? 56.912 6.557 -9.878 1.00 38.07 ? 64 PHE C CD1 1 ATOM 3075 C CD2 . PHE C 1 64 ? 57.504 8.488 -8.602 1.00 37.45 ? 64 PHE C CD2 1 ATOM 3076 C CE1 . PHE C 1 64 ? 58.082 6.678 -10.612 1.00 39.04 ? 64 PHE C CE1 1 ATOM 3077 C CE2 . PHE C 1 64 ? 58.674 8.621 -9.326 1.00 37.19 ? 64 PHE C CE2 1 ATOM 3078 C CZ . PHE C 1 64 ? 58.966 7.719 -10.330 1.00 38.51 ? 64 PHE C CZ 1 ATOM 3079 N N . ASP C 1 65 ? 57.304 4.752 -6.655 1.00 43.35 ? 65 ASP C N 1 ATOM 3080 C CA . ASP C 1 65 ? 58.607 4.521 -6.029 1.00 45.11 ? 65 ASP C CA 1 ATOM 3081 C C . ASP C 1 65 ? 59.723 5.026 -6.942 1.00 46.26 ? 65 ASP C C 1 ATOM 3082 O O . ASP C 1 65 ? 60.093 4.358 -7.922 1.00 46.07 ? 65 ASP C O 1 ATOM 3083 C CB . ASP C 1 65 ? 58.808 3.032 -5.714 1.00 47.07 ? 65 ASP C CB 1 ATOM 3084 C CG . ASP C 1 65 ? 59.935 2.775 -4.695 1.00 49.31 ? 65 ASP C CG 1 ATOM 3085 O OD1 . ASP C 1 65 ? 60.788 3.664 -4.440 1.00 48.52 ? 65 ASP C OD1 1 ATOM 3086 O OD2 . ASP C 1 65 ? 59.966 1.654 -4.142 1.00 50.75 ? 65 ASP C OD2 1 ATOM 3087 N N . ALA C 1 66 ? 60.259 6.201 -6.601 1.00 47.15 ? 66 ALA C N 1 ATOM 3088 C CA . ALA C 1 66 ? 61.303 6.863 -7.387 1.00 49.13 ? 66 ALA C CA 1 ATOM 3089 C C . ALA C 1 66 ? 62.618 6.085 -7.403 1.00 51.06 ? 66 ALA C C 1 ATOM 3090 O O . ALA C 1 66 ? 63.331 6.084 -8.410 1.00 51.10 ? 66 ALA C O 1 ATOM 3091 C CB . ALA C 1 66 ? 61.537 8.264 -6.869 1.00 48.98 ? 66 ALA C CB 1 ATOM 3092 N N . SER C 1 67 ? 62.925 5.425 -6.285 1.00 52.31 ? 67 SER C N 1 ATOM 3093 C CA . SER C 1 67 ? 64.151 4.651 -6.140 1.00 53.04 ? 67 SER C CA 1 ATOM 3094 C C . SER C 1 67 ? 64.190 3.400 -7.024 1.00 53.77 ? 67 SER C C 1 ATOM 3095 O O . SER C 1 67 ? 65.239 2.768 -7.151 1.00 53.86 ? 67 SER C O 1 ATOM 3096 C CB . SER C 1 67 ? 64.374 4.278 -4.670 1.00 54.74 ? 67 SER C CB 1 ATOM 3097 O OG . SER C 1 67 ? 63.493 3.249 -4.245 1.00 56.19 ? 67 SER C OG 1 ATOM 3098 N N . ASP C 1 68 ? 63.059 3.043 -7.633 1.00 54.46 ? 68 ASP C N 1 ATOM 3099 C CA . ASP C 1 68 ? 63.019 1.894 -8.548 1.00 54.62 ? 68 ASP C CA 1 ATOM 3100 C C . ASP C 1 68 ? 63.181 2.271 -10.024 1.00 53.81 ? 68 ASP C C 1 ATOM 3101 O O . ASP C 1 68 ? 63.437 1.408 -10.867 1.00 53.90 ? 68 ASP C O 1 ATOM 3102 C CB . ASP C 1 68 ? 61.754 1.062 -8.331 1.00 56.01 ? 68 ASP C CB 1 ATOM 3103 C CG . ASP C 1 68 ? 61.713 0.406 -6.957 1.00 57.84 ? 68 ASP C CG 1 ATOM 3104 O OD1 . ASP C 1 68 ? 62.795 0.083 -6.418 1.00 58.75 ? 68 ASP C OD1 1 ATOM 3105 O OD2 . ASP C 1 68 ? 60.598 0.213 -6.418 1.00 57.61 ? 68 ASP C OD2 1 ATOM 3106 N N . SER C 1 69 ? 63.046 3.559 -10.330 1.00 53.10 ? 69 SER C N 1 ATOM 3107 C CA . SER C 1 69 ? 63.222 4.049 -11.700 1.00 51.90 ? 69 SER C CA 1 ATOM 3108 C C . SER C 1 69 ? 64.661 4.502 -11.946 1.00 50.70 ? 69 SER C C 1 ATOM 3109 O O . SER C 1 69 ? 65.163 5.398 -11.263 1.00 49.75 ? 69 SER C O 1 ATOM 3110 C CB . SER C 1 69 ? 62.242 5.188 -12.000 1.00 51.29 ? 69 SER C CB 1 ATOM 3111 O OG . SER C 1 69 ? 62.494 5.759 -13.278 1.00 50.89 ? 69 SER C OG 1 ATOM 3112 N N . SER C 1 70 ? 65.312 3.889 -12.932 1.00 50.80 ? 70 SER C N 1 ATOM 3113 C CA . SER C 1 70 ? 66.686 4.246 -13.290 1.00 50.91 ? 70 SER C CA 1 ATOM 3114 C C . SER C 1 70 ? 66.766 5.571 -14.053 1.00 51.04 ? 70 SER C C 1 ATOM 3115 O O . SER C 1 70 ? 67.840 6.178 -14.139 1.00 51.66 ? 70 SER C O 1 ATOM 3116 C CB . SER C 1 70 ? 67.366 3.113 -14.073 1.00 51.57 ? 70 SER C CB 1 ATOM 3117 O OG . SER C 1 70 ? 66.955 3.063 -15.429 1.00 51.77 ? 70 SER C OG 1 ATOM 3118 N N . SER C 1 71 ? 65.623 6.018 -14.582 1.00 50.35 ? 71 SER C N 1 ATOM 3119 C CA . SER C 1 71 ? 65.528 7.262 -15.355 1.00 48.64 ? 71 SER C CA 1 ATOM 3120 C C . SER C 1 71 ? 65.031 8.451 -14.539 1.00 48.40 ? 71 SER C C 1 ATOM 3121 O O . SER C 1 71 ? 64.959 9.562 -15.053 1.00 48.43 ? 71 SER C O 1 ATOM 3122 C CB . SER C 1 71 ? 64.630 7.069 -16.583 1.00 48.08 ? 71 SER C CB 1 ATOM 3123 O OG . SER C 1 71 ? 63.386 6.479 -16.237 1.00 47.11 ? 71 SER C OG 1 ATOM 3124 N N . TYR C 1 72 ? 64.686 8.219 -13.274 1.00 48.24 ? 72 TYR C N 1 ATOM 3125 C CA . TYR C 1 72 ? 64.168 9.282 -12.402 1.00 48.43 ? 72 TYR C CA 1 ATOM 3126 C C . TYR C 1 72 ? 65.202 10.385 -12.123 1.00 49.47 ? 72 TYR C C 1 ATOM 3127 O O . TYR C 1 72 ? 66.399 10.120 -11.970 1.00 48.77 ? 72 TYR C O 1 ATOM 3128 C CB . TYR C 1 72 ? 63.614 8.683 -11.095 1.00 47.91 ? 72 TYR C CB 1 ATOM 3129 C CG . TYR C 1 72 ? 63.502 9.650 -9.938 1.00 47.70 ? 72 TYR C CG 1 ATOM 3130 C CD1 . TYR C 1 72 ? 64.512 9.730 -8.975 1.00 48.64 ? 72 TYR C CD1 1 ATOM 3131 C CD2 . TYR C 1 72 ? 62.396 10.485 -9.798 1.00 47.58 ? 72 TYR C CD2 1 ATOM 3132 C CE1 . TYR C 1 72 ? 64.427 10.617 -7.907 1.00 48.08 ? 72 TYR C CE1 1 ATOM 3133 C CE2 . TYR C 1 72 ? 62.297 11.380 -8.724 1.00 47.73 ? 72 TYR C CE2 1 ATOM 3134 C CZ . TYR C 1 72 ? 63.319 11.436 -7.783 1.00 48.07 ? 72 TYR C CZ 1 ATOM 3135 O OH . TYR C 1 72 ? 63.247 12.308 -6.717 1.00 47.98 ? 72 TYR C OH 1 ATOM 3136 N N . LYS C 1 73 ? 64.727 11.625 -12.079 1.00 50.99 ? 73 LYS C N 1 ATOM 3137 C CA . LYS C 1 73 ? 65.560 12.752 -11.680 1.00 52.53 ? 73 LYS C CA 1 ATOM 3138 C C . LYS C 1 73 ? 64.850 13.579 -10.620 1.00 53.29 ? 73 LYS C C 1 ATOM 3139 O O . LYS C 1 73 ? 63.671 13.927 -10.763 1.00 52.78 ? 73 LYS C O 1 ATOM 3140 C CB . LYS C 1 73 ? 65.982 13.605 -12.883 1.00 54.65 ? 73 LYS C CB 1 ATOM 3141 C CG . LYS C 1 73 ? 67.114 12.970 -13.694 1.00 57.22 ? 73 LYS C CG 1 ATOM 3142 C CD . LYS C 1 73 ? 68.120 14.004 -14.211 1.00 59.59 ? 73 LYS C CD 1 ATOM 3143 C CE . LYS C 1 73 ? 67.971 14.235 -15.717 1.00 60.97 ? 73 LYS C CE 1 ATOM 3144 N NZ . LYS C 1 73 ? 69.079 15.073 -16.267 1.00 62.01 ? 73 LYS C NZ 1 ATOM 3145 N N . HIS C 1 74 ? 65.575 13.848 -9.538 1.00 52.92 ? 74 HIS C N 1 ATOM 3146 C CA . HIS C 1 74 ? 65.068 14.609 -8.406 1.00 53.17 ? 74 HIS C CA 1 ATOM 3147 C C . HIS C 1 74 ? 64.906 16.077 -8.785 1.00 51.89 ? 74 HIS C C 1 ATOM 3148 O O . HIS C 1 74 ? 65.685 16.618 -9.569 1.00 51.87 ? 74 HIS C O 1 ATOM 3149 C CB . HIS C 1 74 ? 66.016 14.455 -7.201 1.00 54.83 ? 74 HIS C CB 1 ATOM 3150 C CG . HIS C 1 74 ? 65.705 15.373 -6.058 1.00 56.57 ? 74 HIS C CG 1 ATOM 3151 N ND1 . HIS C 1 74 ? 66.201 16.658 -5.978 1.00 57.62 ? 74 HIS C ND1 1 ATOM 3152 C CD2 . HIS C 1 74 ? 64.945 15.195 -4.951 1.00 57.28 ? 74 HIS C CD2 1 ATOM 3153 C CE1 . HIS C 1 74 ? 65.758 17.232 -4.873 1.00 57.68 ? 74 HIS C CE1 1 ATOM 3154 N NE2 . HIS C 1 74 ? 64.995 16.366 -4.231 1.00 57.84 ? 74 HIS C NE2 1 ATOM 3155 N N . ASN C 1 75 ? 63.877 16.710 -8.242 1.00 51.71 ? 75 ASN C N 1 ATOM 3156 C CA . ASN C 1 75 ? 63.720 18.152 -8.366 1.00 52.22 ? 75 ASN C CA 1 ATOM 3157 C C . ASN C 1 75 ? 63.433 18.711 -6.983 1.00 52.39 ? 75 ASN C C 1 ATOM 3158 O O . ASN C 1 75 ? 64.286 19.371 -6.393 1.00 53.91 ? 75 ASN C O 1 ATOM 3159 C CB . ASN C 1 75 ? 62.627 18.515 -9.382 1.00 52.00 ? 75 ASN C CB 1 ATOM 3160 C CG . ASN C 1 75 ? 62.533 20.011 -9.632 1.00 52.17 ? 75 ASN C CG 1 ATOM 3161 O OD1 . ASN C 1 75 ? 62.036 20.755 -8.791 1.00 52.01 ? 75 ASN C OD1 1 ATOM 3162 N ND2 . ASN C 1 75 ? 63.001 20.456 -10.798 1.00 52.64 ? 75 ASN C ND2 1 ATOM 3163 N N . GLY C 1 76 ? 62.244 18.423 -6.463 1.00 51.33 ? 76 GLY C N 1 ATOM 3164 C CA . GLY C 1 76 ? 61.921 18.735 -5.086 1.00 50.64 ? 76 GLY C CA 1 ATOM 3165 C C . GLY C 1 76 ? 61.089 19.980 -4.874 1.00 51.32 ? 76 GLY C C 1 ATOM 3166 O O . GLY C 1 76 ? 60.563 20.186 -3.773 1.00 50.41 ? 76 GLY C O 1 ATOM 3167 N N . THR C 1 77 ? 60.967 20.814 -5.908 1.00 52.08 ? 77 THR C N 1 ATOM 3168 C CA . THR C 1 77 ? 60.138 22.006 -5.803 1.00 54.11 ? 77 THR C CA 1 ATOM 3169 C C . THR C 1 77 ? 58.766 21.587 -5.306 1.00 55.77 ? 77 THR C C 1 ATOM 3170 O O . THR C 1 77 ? 58.074 20.789 -5.944 1.00 56.69 ? 77 THR C O 1 ATOM 3171 C CB . THR C 1 77 ? 60.005 22.782 -7.129 1.00 54.30 ? 77 THR C CB 1 ATOM 3172 O OG1 . THR C 1 77 ? 61.304 23.071 -7.645 1.00 56.11 ? 77 THR C OG1 1 ATOM 3173 C CG2 . THR C 1 77 ? 59.277 24.109 -6.906 1.00 54.95 ? 77 THR C CG2 1 ATOM 3174 N N . GLU C 1 78 ? 58.401 22.104 -4.142 1.00 57.57 ? 78 GLU C N 1 ATOM 3175 C CA . GLU C 1 78 ? 57.124 21.789 -3.528 1.00 59.36 ? 78 GLU C CA 1 ATOM 3176 C C . GLU C 1 78 ? 56.025 22.524 -4.269 1.00 59.34 ? 78 GLU C C 1 ATOM 3177 O O . GLU C 1 78 ? 56.212 23.666 -4.691 1.00 59.80 ? 78 GLU C O 1 ATOM 3178 C CB . GLU C 1 78 ? 57.148 22.156 -2.043 1.00 61.53 ? 78 GLU C CB 1 ATOM 3179 C CG . GLU C 1 78 ? 57.870 21.109 -1.189 1.00 64.69 ? 78 GLU C CG 1 ATOM 3180 C CD . GLU C 1 78 ? 58.737 21.712 -0.094 1.00 67.35 ? 78 GLU C CD 1 ATOM 3181 O OE1 . GLU C 1 78 ? 58.240 22.576 0.673 1.00 67.45 ? 78 GLU C OE1 1 ATOM 3182 O OE2 . GLU C 1 78 ? 59.920 21.304 0.002 1.00 68.80 ? 78 GLU C OE2 1 ATOM 3183 N N . LEU C 1 79 ? 54.892 21.854 -4.452 1.00 58.72 ? 79 LEU C N 1 ATOM 3184 C CA . LEU C 1 79 ? 53.763 22.451 -5.147 1.00 58.27 ? 79 LEU C CA 1 ATOM 3185 C C . LEU C 1 79 ? 52.424 22.026 -4.560 1.00 58.40 ? 79 LEU C C 1 ATOM 3186 O O . LEU C 1 79 ? 52.274 20.911 -4.052 1.00 57.45 ? 79 LEU C O 1 ATOM 3187 C CB . LEU C 1 79 ? 53.849 22.212 -6.665 1.00 58.68 ? 79 LEU C CB 1 ATOM 3188 C CG . LEU C 1 79 ? 53.602 20.877 -7.369 1.00 58.61 ? 79 LEU C CG 1 ATOM 3189 C CD1 . LEU C 1 79 ? 53.902 21.051 -8.839 1.00 59.21 ? 79 LEU C CD1 1 ATOM 3190 C CD2 . LEU C 1 79 ? 54.420 19.740 -6.815 1.00 58.76 ? 79 LEU C CD2 1 ATOM 3191 N N . THR C 1 80 ? 51.459 22.936 -4.646 1.00 59.33 ? 80 THR C N 1 ATOM 3192 C CA . THR C 1 80 ? 50.220 22.847 -3.891 1.00 60.78 ? 80 THR C CA 1 ATOM 3193 C C . THR C 1 80 ? 48.998 23.144 -4.758 1.00 62.44 ? 80 THR C C 1 ATOM 3194 O O . THR C 1 80 ? 49.036 23.997 -5.646 1.00 61.69 ? 80 THR C O 1 ATOM 3195 C CB . THR C 1 80 ? 50.279 23.799 -2.660 1.00 60.70 ? 80 THR C CB 1 ATOM 3196 O OG1 . THR C 1 80 ? 51.037 23.172 -1.617 1.00 60.46 ? 80 THR C OG1 1 ATOM 3197 C CG2 . THR C 1 80 ? 48.887 24.146 -2.127 1.00 60.65 ? 80 THR C CG2 1 ATOM 3198 N N . LEU C 1 81 ? 47.920 22.418 -4.479 1.00 64.78 ? 81 LEU C N 1 ATOM 3199 C CA . LEU C 1 81 ? 46.638 22.600 -5.136 1.00 66.88 ? 81 LEU C CA 1 ATOM 3200 C C . LEU C 1 81 ? 45.582 22.881 -4.070 1.00 68.36 ? 81 LEU C C 1 ATOM 3201 O O . LEU C 1 81 ? 45.516 22.184 -3.058 1.00 68.04 ? 81 LEU C O 1 ATOM 3202 C CB . LEU C 1 81 ? 46.277 21.318 -5.890 1.00 66.97 ? 81 LEU C CB 1 ATOM 3203 C CG . LEU C 1 81 ? 45.253 21.235 -7.028 1.00 67.62 ? 81 LEU C CG 1 ATOM 3204 C CD1 . LEU C 1 81 ? 44.555 19.898 -6.919 1.00 68.06 ? 81 LEU C CD1 1 ATOM 3205 C CD2 . LEU C 1 81 ? 44.217 22.357 -7.060 1.00 67.87 ? 81 LEU C CD2 1 ATOM 3206 N N . ARG C 1 82 ? 44.759 23.900 -4.299 1.00 71.22 ? 82 ARG C N 1 ATOM 3207 C CA . ARG C 1 82 ? 43.647 24.209 -3.398 1.00 74.38 ? 82 ARG C CA 1 ATOM 3208 C C . ARG C 1 82 ? 42.359 23.509 -3.842 1.00 74.40 ? 82 ARG C C 1 ATOM 3209 O O . ARG C 1 82 ? 41.914 23.666 -4.984 1.00 74.56 ? 82 ARG C O 1 ATOM 3210 C CB . ARG C 1 82 ? 43.454 25.726 -3.264 1.00 75.35 ? 82 ARG C CB 1 ATOM 3211 C CG . ARG C 1 82 ? 44.356 26.360 -2.195 1.00 76.90 ? 82 ARG C CG 1 ATOM 3212 C CD . ARG C 1 82 ? 44.493 27.880 -2.360 1.00 77.09 ? 82 ARG C CD 1 ATOM 3213 N NE . ARG C 1 82 ? 45.195 28.486 -1.223 1.00 78.46 ? 82 ARG C NE 1 ATOM 3214 C CZ . ARG C 1 82 ? 44.602 29.179 -0.250 1.00 78.91 ? 82 ARG C CZ 1 ATOM 3215 N NH1 . ARG C 1 82 ? 43.286 29.375 -0.267 1.00 78.92 ? 82 ARG C NH1 1 ATOM 3216 N NH2 . ARG C 1 82 ? 45.325 29.685 0.743 1.00 78.55 ? 82 ARG C NH2 1 ATOM 3217 N N . TYR C 1 83 ? 41.778 22.729 -2.931 1.00 74.96 ? 83 TYR C N 1 ATOM 3218 C CA . TYR C 1 83 ? 40.631 21.877 -3.245 1.00 75.66 ? 83 TYR C CA 1 ATOM 3219 C C . TYR C 1 83 ? 39.583 21.886 -2.126 1.00 75.75 ? 83 TYR C C 1 ATOM 3220 O O . TYR C 1 83 ? 39.922 21.753 -0.952 1.00 75.87 ? 83 TYR C O 1 ATOM 3221 C CB . TYR C 1 83 ? 41.107 20.446 -3.537 1.00 75.63 ? 83 TYR C CB 1 ATOM 3222 C CG . TYR C 1 83 ? 40.045 19.541 -4.124 1.00 75.38 ? 83 TYR C CG 1 ATOM 3223 C CD1 . TYR C 1 83 ? 39.419 18.573 -3.342 1.00 74.99 ? 83 TYR C CD1 1 ATOM 3224 C CD2 . TYR C 1 83 ? 39.668 19.654 -5.463 1.00 75.57 ? 83 TYR C CD2 1 ATOM 3225 C CE1 . TYR C 1 83 ? 38.442 17.738 -3.878 1.00 75.40 ? 83 TYR C CE1 1 ATOM 3226 C CE2 . TYR C 1 83 ? 38.688 18.825 -6.009 1.00 75.73 ? 83 TYR C CE2 1 ATOM 3227 C CZ . TYR C 1 83 ? 38.083 17.867 -5.212 1.00 75.67 ? 83 TYR C CZ 1 ATOM 3228 O OH . TYR C 1 83 ? 37.117 17.046 -5.750 1.00 75.27 ? 83 TYR C OH 1 ATOM 3229 N N . SER C 1 84 ? 38.313 22.024 -2.511 1.00 75.39 ? 84 SER C N 1 ATOM 3230 C CA . SER C 1 84 ? 37.181 22.201 -1.582 1.00 75.08 ? 84 SER C CA 1 ATOM 3231 C C . SER C 1 84 ? 37.252 21.448 -0.248 1.00 74.71 ? 84 SER C C 1 ATOM 3232 O O . SER C 1 84 ? 36.883 21.993 0.800 1.00 74.82 ? 84 SER C O 1 ATOM 3233 C CB . SER C 1 84 ? 35.860 21.859 -2.280 1.00 75.67 ? 84 SER C CB 1 ATOM 3234 O OG . SER C 1 84 ? 35.436 22.921 -3.113 1.00 76.62 ? 84 SER C OG 1 ATOM 3235 N N . THR C 1 85 ? 37.725 20.205 -0.298 1.00 73.14 ? 85 THR C N 1 ATOM 3236 C CA . THR C 1 85 ? 37.685 19.301 0.853 1.00 71.59 ? 85 THR C CA 1 ATOM 3237 C C . THR C 1 85 ? 39.026 19.182 1.588 1.00 70.24 ? 85 THR C C 1 ATOM 3238 O O . THR C 1 85 ? 39.180 18.353 2.491 1.00 70.24 ? 85 THR C O 1 ATOM 3239 C CB . THR C 1 85 ? 37.200 17.892 0.433 1.00 71.59 ? 85 THR C CB 1 ATOM 3240 O OG1 . THR C 1 85 ? 38.055 17.374 -0.593 1.00 71.16 ? 85 THR C OG1 1 ATOM 3241 C CG2 . THR C 1 85 ? 35.762 17.939 -0.084 1.00 71.94 ? 85 THR C CG2 1 ATOM 3242 N N . GLY C 1 86 ? 39.988 20.015 1.203 1.00 68.58 ? 86 GLY C N 1 ATOM 3243 C CA . GLY C 1 86 ? 41.320 19.987 1.800 1.00 67.08 ? 86 GLY C CA 1 ATOM 3244 C C . GLY C 1 86 ? 42.389 20.512 0.862 1.00 65.96 ? 86 GLY C C 1 ATOM 3245 O O . GLY C 1 86 ? 42.129 21.375 0.021 1.00 66.71 ? 86 GLY C O 1 ATOM 3246 N N . THR C 1 87 ? 43.603 19.991 1.003 1.00 64.12 ? 87 THR C N 1 ATOM 3247 C CA . THR C 1 87 ? 44.708 20.440 0.166 1.00 61.32 ? 87 THR C CA 1 ATOM 3248 C C . THR C 1 87 ? 45.538 19.289 -0.360 1.00 58.76 ? 87 THR C C 1 ATOM 3249 O O . THR C 1 87 ? 45.965 18.403 0.393 1.00 59.40 ? 87 THR C O 1 ATOM 3250 C CB . THR C 1 87 ? 45.594 21.480 0.900 1.00 62.05 ? 87 THR C CB 1 ATOM 3251 O OG1 . THR C 1 87 ? 44.924 22.748 0.886 1.00 63.39 ? 87 THR C OG1 1 ATOM 3252 C CG2 . THR C 1 87 ? 46.961 21.637 0.230 1.00 61.68 ? 87 THR C CG2 1 ATOM 3253 N N . VAL C 1 88 ? 45.750 19.312 -1.670 1.00 54.95 ? 88 VAL C N 1 ATOM 3254 C CA . VAL C 1 88 ? 46.693 18.414 -2.309 1.00 51.40 ? 88 VAL C CA 1 ATOM 3255 C C . VAL C 1 88 ? 48.032 19.138 -2.440 1.00 49.65 ? 88 VAL C C 1 ATOM 3256 O O . VAL C 1 88 ? 48.110 20.242 -2.979 1.00 49.33 ? 88 VAL C O 1 ATOM 3257 C CB . VAL C 1 88 ? 46.181 17.931 -3.683 1.00 49.23 ? 88 VAL C CB 1 ATOM 3258 C CG1 . VAL C 1 88 ? 47.181 16.995 -4.328 1.00 47.79 ? 88 VAL C CG1 1 ATOM 3259 C CG2 . VAL C 1 88 ? 44.838 17.239 -3.523 1.00 48.42 ? 88 VAL C CG2 1 ATOM 3260 N N . SER C 1 89 ? 49.083 18.519 -1.920 1.00 48.02 ? 89 SER C N 1 ATOM 3261 C CA . SER C 1 89 ? 50.407 19.103 -2.008 1.00 47.07 ? 89 SER C CA 1 ATOM 3262 C C . SER C 1 89 ? 51.427 18.008 -2.185 1.00 44.59 ? 89 SER C C 1 ATOM 3263 O O . SER C 1 89 ? 51.151 16.848 -1.888 1.00 44.12 ? 89 SER C O 1 ATOM 3264 C CB . SER C 1 89 ? 50.719 19.951 -0.765 1.00 48.99 ? 89 SER C CB 1 ATOM 3265 O OG . SER C 1 89 ? 50.722 19.161 0.414 1.00 51.95 ? 89 SER C OG 1 ATOM 3266 N N . GLY C 1 90 ? 52.606 18.383 -2.671 1.00 43.24 ? 90 GLY C N 1 ATOM 3267 C CA . GLY C 1 90 ? 53.671 17.426 -2.940 1.00 41.01 ? 90 GLY C CA 1 ATOM 3268 C C . GLY C 1 90 ? 54.838 18.092 -3.633 1.00 42.06 ? 90 GLY C C 1 ATOM 3269 O O . GLY C 1 90 ? 54.992 19.312 -3.575 1.00 42.25 ? 90 GLY C O 1 ATOM 3270 N N . PHE C 1 91 ? 55.659 17.294 -4.304 1.00 42.78 ? 91 PHE C N 1 ATOM 3271 C CA . PHE C 1 91 ? 56.894 17.809 -4.882 1.00 42.88 ? 91 PHE C CA 1 ATOM 3272 C C . PHE C 1 91 ? 57.073 17.397 -6.339 1.00 44.02 ? 91 PHE C C 1 ATOM 3273 O O . PHE C 1 91 ? 56.552 16.368 -6.782 1.00 43.29 ? 91 PHE C O 1 ATOM 3274 C CB . PHE C 1 91 ? 58.112 17.390 -4.038 1.00 41.61 ? 91 PHE C CB 1 ATOM 3275 C CG . PHE C 1 91 ? 58.291 15.898 -3.915 1.00 40.38 ? 91 PHE C CG 1 ATOM 3276 C CD1 . PHE C 1 91 ? 59.132 15.213 -4.785 1.00 40.52 ? 91 PHE C CD1 1 ATOM 3277 C CD2 . PHE C 1 91 ? 57.623 15.179 -2.924 1.00 40.91 ? 91 PHE C CD2 1 ATOM 3278 C CE1 . PHE C 1 91 ? 59.302 13.826 -4.675 1.00 40.79 ? 91 PHE C CE1 1 ATOM 3279 C CE2 . PHE C 1 91 ? 57.781 13.789 -2.804 1.00 39.86 ? 91 PHE C CE2 1 ATOM 3280 C CZ . PHE C 1 91 ? 58.615 13.115 -3.681 1.00 40.57 ? 91 PHE C CZ 1 ATOM 3281 N N . LEU C 1 92 ? 57.816 18.220 -7.071 1.00 45.32 ? 92 LEU C N 1 ATOM 3282 C CA . LEU C 1 92 ? 58.138 17.957 -8.450 1.00 44.73 ? 92 LEU C CA 1 ATOM 3283 C C . LEU C 1 92 ? 59.149 16.835 -8.578 1.00 45.16 ? 92 LEU C C 1 ATOM 3284 O O . LEU C 1 92 ? 60.133 16.785 -7.845 1.00 47.05 ? 92 LEU C O 1 ATOM 3285 C CB . LEU C 1 92 ? 58.712 19.207 -9.100 1.00 46.64 ? 92 LEU C CB 1 ATOM 3286 C CG . LEU C 1 92 ? 57.778 20.277 -9.660 1.00 48.30 ? 92 LEU C CG 1 ATOM 3287 C CD1 . LEU C 1 92 ? 58.621 21.325 -10.377 1.00 48.12 ? 92 LEU C CD1 1 ATOM 3288 C CD2 . LEU C 1 92 ? 56.752 19.673 -10.617 1.00 48.27 ? 92 LEU C CD2 1 ATOM 3289 N N . SER C 1 93 ? 58.886 15.931 -9.510 1.00 43.13 ? 93 SER C N 1 ATOM 3290 C CA . SER C 1 93 ? 59.872 14.980 -9.963 1.00 43.40 ? 93 SER C CA 1 ATOM 3291 C C . SER C 1 93 ? 59.888 15.022 -11.484 1.00 44.02 ? 93 SER C C 1 ATOM 3292 O O . SER C 1 93 ? 58.947 15.528 -12.107 1.00 43.69 ? 93 SER C O 1 ATOM 3293 C CB . SER C 1 93 ? 59.531 13.570 -9.484 1.00 43.52 ? 93 SER C CB 1 ATOM 3294 O OG . SER C 1 93 ? 59.533 13.483 -8.072 1.00 44.00 ? 93 SER C OG 1 ATOM 3295 N N . GLN C 1 94 ? 60.957 14.500 -12.074 1.00 43.29 ? 94 GLN C N 1 ATOM 3296 C CA . GLN C 1 94 ? 61.051 14.357 -13.516 1.00 44.38 ? 94 GLN C CA 1 ATOM 3297 C C . GLN C 1 94 ? 61.324 12.899 -13.822 1.00 44.34 ? 94 GLN C C 1 ATOM 3298 O O . GLN C 1 94 ? 62.115 12.255 -13.122 1.00 45.34 ? 94 GLN C O 1 ATOM 3299 C CB . GLN C 1 94 ? 62.178 15.220 -14.082 1.00 45.15 ? 94 GLN C CB 1 ATOM 3300 C CG . GLN C 1 94 ? 62.234 15.229 -15.614 1.00 46.77 ? 94 GLN C CG 1 ATOM 3301 C CD . GLN C 1 94 ? 63.533 15.794 -16.162 1.00 46.65 ? 94 GLN C CD 1 ATOM 3302 O OE1 . GLN C 1 94 ? 63.579 16.937 -16.616 1.00 48.16 ? 94 GLN C OE1 1 ATOM 3303 N NE2 . GLN C 1 94 ? 64.594 14.994 -16.122 1.00 46.38 ? 94 GLN C NE2 1 ATOM 3304 N N . ASP C 1 95 ? 60.662 12.380 -14.855 1.00 42.75 ? 95 ASP C N 1 ATOM 3305 C CA . ASP C 1 95 ? 60.847 11.000 -15.285 1.00 41.46 ? 95 ASP C CA 1 ATOM 3306 C C . ASP C 1 95 ? 60.217 10.777 -16.659 1.00 42.14 ? 95 ASP C C 1 ATOM 3307 O O . ASP C 1 95 ? 59.580 11.676 -17.211 1.00 43.00 ? 95 ASP C O 1 ATOM 3308 C CB . ASP C 1 95 ? 60.259 10.026 -14.256 1.00 40.45 ? 95 ASP C CB 1 ATOM 3309 C CG . ASP C 1 95 ? 60.995 8.685 -14.220 1.00 40.88 ? 95 ASP C CG 1 ATOM 3310 O OD1 . ASP C 1 95 ? 61.607 8.299 -15.237 1.00 38.70 ? 95 ASP C OD1 1 ATOM 3311 O OD2 . ASP C 1 95 ? 60.946 8.005 -13.170 1.00 41.32 ? 95 ASP C OD2 1 ATOM 3312 N N . ILE C 1 96 ? 60.418 9.579 -17.203 1.00 40.79 ? 96 ILE C N 1 ATOM 3313 C CA . ILE C 1 96 ? 59.842 9.180 -18.472 1.00 39.55 ? 96 ILE C CA 1 ATOM 3314 C C . ILE C 1 96 ? 58.432 8.636 -18.275 1.00 40.15 ? 96 ILE C C 1 ATOM 3315 O O . ILE C 1 96 ? 58.216 7.647 -17.554 1.00 39.43 ? 96 ILE C O 1 ATOM 3316 C CB . ILE C 1 96 ? 60.707 8.118 -19.175 1.00 39.19 ? 96 ILE C CB 1 ATOM 3317 C CG1 . ILE C 1 96 ? 62.077 8.718 -19.521 1.00 38.99 ? 96 ILE C CG1 1 ATOM 3318 C CG2 . ILE C 1 96 ? 59.981 7.578 -20.424 1.00 38.61 ? 96 ILE C CG2 1 ATOM 3319 C CD1 . ILE C 1 96 ? 63.078 7.724 -20.082 1.00 40.41 ? 96 ILE C CD1 1 ATOM 3320 N N . ILE C 1 97 ? 57.477 9.294 -18.925 1.00 38.95 ? 97 ILE C N 1 ATOM 3321 C CA . ILE C 1 97 ? 56.094 8.854 -18.903 1.00 37.05 ? 97 ILE C CA 1 ATOM 3322 C C . ILE C 1 97 ? 55.742 8.295 -20.275 1.00 38.39 ? 97 ILE C C 1 ATOM 3323 O O . ILE C 1 97 ? 55.982 8.941 -21.304 1.00 35.84 ? 97 ILE C O 1 ATOM 3324 C CB . ILE C 1 97 ? 55.131 9.988 -18.456 1.00 36.04 ? 97 ILE C CB 1 ATOM 3325 C CG1 . ILE C 1 97 ? 55.512 10.468 -17.038 1.00 36.87 ? 97 ILE C CG1 1 ATOM 3326 C CG2 . ILE C 1 97 ? 53.689 9.515 -18.515 1.00 35.35 ? 97 ILE C CG2 1 ATOM 3327 C CD1 . ILE C 1 97 ? 54.570 11.509 -16.392 1.00 36.49 ? 97 ILE C CD1 1 ATOM 3328 N N . THR C 1 98 ? 55.226 7.066 -20.285 1.00 39.57 ? 98 THR C N 1 ATOM 3329 C CA . THR C 1 98 ? 54.719 6.466 -21.511 1.00 41.00 ? 98 THR C CA 1 ATOM 3330 C C . THR C 1 98 ? 53.186 6.560 -21.544 1.00 41.27 ? 98 THR C C 1 ATOM 3331 O O . THR C 1 98 ? 52.491 5.988 -20.688 1.00 39.67 ? 98 THR C O 1 ATOM 3332 C CB . THR C 1 98 ? 55.206 5.024 -21.715 1.00 41.60 ? 98 THR C CB 1 ATOM 3333 O OG1 . THR C 1 98 ? 54.799 4.230 -20.606 1.00 44.99 ? 98 THR C OG1 1 ATOM 3334 C CG2 . THR C 1 98 ? 56.708 4.976 -21.786 1.00 43.24 ? 98 THR C CG2 1 ATOM 3335 N N . VAL C 1 99 ? 52.685 7.322 -22.517 1.00 41.20 ? 99 VAL C N 1 ATOM 3336 C CA . VAL C 1 99 ? 51.255 7.444 -22.776 1.00 43.56 ? 99 VAL C CA 1 ATOM 3337 C C . VAL C 1 99 ? 50.952 6.934 -24.178 1.00 42.49 ? 99 VAL C C 1 ATOM 3338 O O . VAL C 1 99 ? 51.467 7.466 -25.154 1.00 43.45 ? 99 VAL C O 1 ATOM 3339 C CB . VAL C 1 99 ? 50.778 8.906 -22.691 1.00 45.08 ? 99 VAL C CB 1 ATOM 3340 C CG1 . VAL C 1 99 ? 49.259 8.966 -22.540 1.00 45.56 ? 99 VAL C CG1 1 ATOM 3341 C CG2 . VAL C 1 99 ? 51.432 9.605 -21.542 1.00 47.13 ? 99 VAL C CG2 1 ATOM 3342 N N . GLY C 1 100 ? 50.122 5.898 -24.268 1.00 42.24 ? 100 GLY C N 1 ATOM 3343 C CA . GLY C 1 100 ? 49.719 5.306 -25.549 1.00 39.98 ? 100 GLY C CA 1 ATOM 3344 C C . GLY C 1 100 ? 50.882 4.892 -26.431 1.00 39.56 ? 100 GLY C C 1 ATOM 3345 O O . GLY C 1 100 ? 50.812 5.000 -27.652 1.00 39.63 ? 100 GLY C O 1 ATOM 3346 N N . GLY C 1 101 ? 51.959 4.421 -25.808 1.00 39.54 ? 101 GLY C N 1 ATOM 3347 C CA . GLY C 1 101 ? 53.164 4.019 -26.533 1.00 38.04 ? 101 GLY C CA 1 ATOM 3348 C C . GLY C 1 101 ? 54.143 5.155 -26.776 1.00 36.24 ? 101 GLY C C 1 ATOM 3349 O O . GLY C 1 101 ? 55.272 4.914 -27.185 1.00 36.10 ? 101 GLY C O 1 ATOM 3350 N N . ILE C 1 102 ? 53.706 6.389 -26.539 1.00 35.64 ? 102 ILE C N 1 ATOM 3351 C CA . ILE C 1 102 ? 54.561 7.562 -26.704 1.00 36.43 ? 102 ILE C CA 1 ATOM 3352 C C . ILE C 1 102 ? 55.376 7.737 -25.433 1.00 37.05 ? 102 ILE C C 1 ATOM 3353 O O . ILE C 1 102 ? 54.823 7.721 -24.328 1.00 36.37 ? 102 ILE C O 1 ATOM 3354 C CB . ILE C 1 102 ? 53.753 8.871 -26.972 1.00 36.48 ? 102 ILE C CB 1 ATOM 3355 C CG1 . ILE C 1 102 ? 52.724 8.670 -28.102 1.00 37.11 ? 102 ILE C CG1 1 ATOM 3356 C CG2 . ILE C 1 102 ? 54.697 10.032 -27.273 1.00 36.22 ? 102 ILE C CG2 1 ATOM 3357 C CD1 . ILE C 1 102 ? 52.101 9.965 -28.664 1.00 35.59 ? 102 ILE C CD1 1 ATOM 3358 N N . THR C 1 103 ? 56.686 7.884 -25.604 1.00 36.63 ? 103 THR C N 1 ATOM 3359 C CA . THR C 1 103 ? 57.622 8.094 -24.498 1.00 37.88 ? 103 THR C CA 1 ATOM 3360 C C . THR C 1 103 ? 57.959 9.568 -24.391 1.00 37.65 ? 103 THR C C 1 ATOM 3361 O O . THR C 1 103 ? 58.376 10.191 -25.370 1.00 40.02 ? 103 THR C O 1 ATOM 3362 C CB . THR C 1 103 ? 58.902 7.240 -24.686 1.00 39.98 ? 103 THR C CB 1 ATOM 3363 O OG1 . THR C 1 103 ? 58.751 6.001 -23.990 1.00 40.03 ? 103 THR C OG1 1 ATOM 3364 C CG2 . THR C 1 103 ? 60.137 7.937 -24.147 1.00 42.66 ? 103 THR C CG2 1 ATOM 3365 N N . VAL C 1 104 ? 57.770 10.130 -23.205 1.00 37.94 ? 104 VAL C N 1 ATOM 3366 C CA . VAL C 1 104 ? 58.031 11.548 -22.996 1.00 38.83 ? 104 VAL C CA 1 ATOM 3367 C C . VAL C 1 104 ? 58.614 11.833 -21.611 1.00 40.40 ? 104 VAL C C 1 ATOM 3368 O O . VAL C 1 104 ? 58.104 11.349 -20.590 1.00 40.92 ? 104 VAL C O 1 ATOM 3369 C CB . VAL C 1 104 ? 56.771 12.436 -23.300 1.00 39.32 ? 104 VAL C CB 1 ATOM 3370 C CG1 . VAL C 1 104 ? 55.498 11.870 -22.674 1.00 38.83 ? 104 VAL C CG1 1 ATOM 3371 C CG2 . VAL C 1 104 ? 56.988 13.892 -22.874 1.00 39.61 ? 104 VAL C CG2 1 ATOM 3372 N N . THR C 1 105 ? 59.697 12.608 -21.596 1.00 40.37 ? 105 THR C N 1 ATOM 3373 C CA . THR C 1 105 ? 60.283 13.111 -20.358 1.00 40.01 ? 105 THR C CA 1 ATOM 3374 C C . THR C 1 105 ? 59.364 14.198 -19.822 1.00 39.71 ? 105 THR C C 1 ATOM 3375 O O . THR C 1 105 ? 59.078 15.172 -20.516 1.00 40.88 ? 105 THR C O 1 ATOM 3376 C CB . THR C 1 105 ? 61.720 13.644 -20.588 1.00 39.33 ? 105 THR C CB 1 ATOM 3377 O OG1 . THR C 1 105 ? 62.567 12.559 -20.998 1.00 37.99 ? 105 THR C OG1 1 ATOM 3378 C CG2 . THR C 1 105 ? 62.289 14.281 -19.309 1.00 39.82 ? 105 THR C CG2 1 ATOM 3379 N N . GLN C 1 106 ? 58.889 14.013 -18.593 1.00 39.39 ? 106 GLN C N 1 ATOM 3380 C CA . GLN C 1 106 ? 57.838 14.859 -18.030 1.00 38.53 ? 106 GLN C CA 1 ATOM 3381 C C . GLN C 1 106 ? 58.094 15.206 -16.570 1.00 39.19 ? 106 GLN C C 1 ATOM 3382 O O . GLN C 1 106 ? 58.540 14.358 -15.799 1.00 39.81 ? 106 GLN C O 1 ATOM 3383 C CB . GLN C 1 106 ? 56.480 14.148 -18.153 1.00 37.61 ? 106 GLN C CB 1 ATOM 3384 C CG . GLN C 1 106 ? 55.266 14.970 -17.704 1.00 35.60 ? 106 GLN C CG 1 ATOM 3385 C CD . GLN C 1 106 ? 55.054 16.213 -18.541 1.00 33.98 ? 106 GLN C CD 1 ATOM 3386 O OE1 . GLN C 1 106 ? 55.328 16.218 -19.735 1.00 35.57 ? 106 GLN C OE1 1 ATOM 3387 N NE2 . GLN C 1 106 ? 54.582 17.280 -17.915 1.00 32.95 ? 106 GLN C NE2 1 ATOM 3388 N N . MET C 1 107 ? 57.802 16.454 -16.207 1.00 38.86 ? 107 MET C N 1 ATOM 3389 C CA . MET C 1 107 ? 57.764 16.878 -14.816 1.00 39.61 ? 107 MET C CA 1 ATOM 3390 C C . MET C 1 107 ? 56.359 16.649 -14.286 1.00 38.09 ? 107 MET C C 1 ATOM 3391 O O . MET C 1 107 ? 55.378 17.137 -14.862 1.00 37.14 ? 107 MET C O 1 ATOM 3392 C CB . MET C 1 107 ? 58.098 18.365 -14.653 1.00 43.28 ? 107 MET C CB 1 ATOM 3393 C CG . MET C 1 107 ? 59.250 18.890 -15.466 1.00 47.56 ? 107 MET C CG 1 ATOM 3394 S SD . MET C 1 107 ? 60.824 18.491 -14.726 1.00 54.45 ? 107 MET C SD 1 ATOM 3395 C CE . MET C 1 107 ? 60.638 19.218 -13.090 1.00 52.86 ? 107 MET C CE 1 ATOM 3396 N N . PHE C 1 108 ? 56.276 15.940 -13.166 1.00 36.36 ? 108 PHE C N 1 ATOM 3397 C CA . PHE C 1 108 ? 55.005 15.557 -12.573 1.00 36.54 ? 108 PHE C CA 1 ATOM 3398 C C . PHE C 1 108 ? 55.053 15.757 -11.073 1.00 38.18 ? 108 PHE C C 1 ATOM 3399 O O . PHE C 1 108 ? 56.128 15.760 -10.474 1.00 39.48 ? 108 PHE C O 1 ATOM 3400 C CB . PHE C 1 108 ? 54.661 14.095 -12.902 1.00 34.58 ? 108 PHE C CB 1 ATOM 3401 C CG . PHE C 1 108 ? 55.703 13.104 -12.467 1.00 33.29 ? 108 PHE C CG 1 ATOM 3402 C CD1 . PHE C 1 108 ? 56.886 12.956 -13.182 1.00 33.56 ? 108 PHE C CD1 1 ATOM 3403 C CD2 . PHE C 1 108 ? 55.491 12.299 -11.351 1.00 34.44 ? 108 PHE C CD2 1 ATOM 3404 C CE1 . PHE C 1 108 ? 57.868 12.033 -12.769 1.00 34.13 ? 108 PHE C CE1 1 ATOM 3405 C CE2 . PHE C 1 108 ? 56.457 11.367 -10.935 1.00 34.45 ? 108 PHE C CE2 1 ATOM 3406 C CZ . PHE C 1 108 ? 57.646 11.236 -11.649 1.00 33.48 ? 108 PHE C CZ 1 ATOM 3407 N N . GLY C 1 109 ? 53.884 15.933 -10.471 1.00 38.12 ? 109 GLY C N 1 ATOM 3408 C CA . GLY C 1 109 ? 53.790 16.006 -9.030 1.00 39.83 ? 109 GLY C CA 1 ATOM 3409 C C . GLY C 1 109 ? 53.678 14.631 -8.404 1.00 40.60 ? 109 GLY C C 1 ATOM 3410 O O . GLY C 1 109 ? 52.846 13.812 -8.814 1.00 38.19 ? 109 GLY C O 1 ATOM 3411 N N . GLU C 1 110 ? 54.553 14.373 -7.435 1.00 41.50 ? 110 GLU C N 1 ATOM 3412 C CA . GLU C 1 110 ? 54.379 13.267 -6.512 1.00 42.57 ? 110 GLU C CA 1 ATOM 3413 C C . GLU C 1 110 ? 53.597 13.821 -5.322 1.00 44.30 ? 110 GLU C C 1 ATOM 3414 O O . GLU C 1 110 ? 54.041 14.780 -4.682 1.00 46.49 ? 110 GLU C O 1 ATOM 3415 C CB . GLU C 1 110 ? 55.732 12.738 -6.054 1.00 42.99 ? 110 GLU C CB 1 ATOM 3416 C CG . GLU C 1 110 ? 56.501 11.970 -7.104 1.00 42.91 ? 110 GLU C CG 1 ATOM 3417 C CD . GLU C 1 110 ? 57.586 11.106 -6.501 1.00 43.11 ? 110 GLU C CD 1 ATOM 3418 O OE1 . GLU C 1 110 ? 57.270 10.311 -5.592 1.00 43.78 ? 110 GLU C OE1 1 ATOM 3419 O OE2 . GLU C 1 110 ? 58.753 11.210 -6.941 1.00 43.66 ? 110 GLU C OE2 1 ATOM 3420 N N . VAL C 1 111 ? 52.435 13.235 -5.037 1.00 43.69 ? 111 VAL C N 1 ATOM 3421 C CA . VAL C 1 111 ? 51.559 13.720 -3.970 1.00 43.88 ? 111 VAL C CA 1 ATOM 3422 C C . VAL C 1 111 ? 51.897 13.027 -2.656 1.00 45.62 ? 111 VAL C C 1 ATOM 3423 O O . VAL C 1 111 ? 51.938 11.794 -2.591 1.00 44.38 ? 111 VAL C O 1 ATOM 3424 C CB . VAL C 1 111 ? 50.056 13.525 -4.324 1.00 43.60 ? 111 VAL C CB 1 ATOM 3425 C CG1 . VAL C 1 111 ? 49.144 13.735 -3.094 1.00 42.58 ? 111 VAL C CG1 1 ATOM 3426 C CG2 . VAL C 1 111 ? 49.651 14.462 -5.454 1.00 42.60 ? 111 VAL C CG2 1 ATOM 3427 N N . THR C 1 112 ? 52.148 13.826 -1.618 1.00 46.92 ? 112 THR C N 1 ATOM 3428 C CA . THR C 1 112 ? 52.519 13.285 -0.310 1.00 48.32 ? 112 THR C CA 1 ATOM 3429 C C . THR C 1 112 ? 51.485 13.610 0.747 1.00 50.41 ? 112 THR C C 1 ATOM 3430 O O . THR C 1 112 ? 51.569 13.119 1.880 1.00 51.15 ? 112 THR C O 1 ATOM 3431 C CB . THR C 1 112 ? 53.905 13.766 0.178 1.00 47.40 ? 112 THR C CB 1 ATOM 3432 O OG1 . THR C 1 112 ? 53.940 15.196 0.213 1.00 47.01 ? 112 THR C OG1 1 ATOM 3433 C CG2 . THR C 1 112 ? 55.017 13.233 -0.711 1.00 46.68 ? 112 THR C CG2 1 ATOM 3434 N N . GLU C 1 113 ? 50.512 14.438 0.379 1.00 51.54 ? 113 GLU C N 1 ATOM 3435 C CA . GLU C 1 113 ? 49.380 14.684 1.253 1.00 54.06 ? 113 GLU C CA 1 ATOM 3436 C C . GLU C 1 113 ? 48.146 15.144 0.494 1.00 53.61 ? 113 GLU C C 1 ATOM 3437 O O . GLU C 1 113 ? 48.227 16.023 -0.369 1.00 54.25 ? 113 GLU C O 1 ATOM 3438 C CB . GLU C 1 113 ? 49.767 15.643 2.384 1.00 55.12 ? 113 GLU C CB 1 ATOM 3439 C CG . GLU C 1 113 ? 49.391 17.098 2.226 1.00 56.50 ? 113 GLU C CG 1 ATOM 3440 C CD . GLU C 1 113 ? 49.811 17.909 3.438 1.00 57.39 ? 113 GLU C CD 1 ATOM 3441 O OE1 . GLU C 1 113 ? 49.045 18.821 3.845 1.00 58.02 ? 113 GLU C OE1 1 ATOM 3442 O OE2 . GLU C 1 113 ? 50.903 17.619 3.990 1.00 58.33 ? 113 GLU C OE2 1 ATOM 3443 N N . MET C 1 114 ? 47.015 14.514 0.810 1.00 53.31 ? 114 MET C N 1 ATOM 3444 C CA . MET C 1 114 ? 45.722 14.851 0.211 1.00 53.59 ? 114 MET C CA 1 ATOM 3445 C C . MET C 1 114 ? 44.571 14.431 1.135 1.00 51.31 ? 114 MET C C 1 ATOM 3446 O O . MET C 1 114 ? 44.728 13.502 1.928 1.00 51.56 ? 114 MET C O 1 ATOM 3447 C CB . MET C 1 114 ? 45.585 14.220 -1.191 1.00 54.18 ? 114 MET C CB 1 ATOM 3448 C CG . MET C 1 114 ? 45.263 12.719 -1.224 1.00 55.62 ? 114 MET C CG 1 ATOM 3449 S SD . MET C 1 114 ? 45.562 11.869 -2.806 1.00 56.81 ? 114 MET C SD 1 ATOM 3450 C CE . MET C 1 114 ? 45.231 13.175 -3.986 1.00 56.59 ? 114 MET C CE 1 ATOM 3451 N N . PRO C 1 115 ? 43.420 15.129 1.056 1.00 50.14 ? 115 PRO C N 1 ATOM 3452 C CA . PRO C 1 115 ? 42.232 14.732 1.817 1.00 49.44 ? 115 PRO C CA 1 ATOM 3453 C C . PRO C 1 115 ? 41.702 13.343 1.469 1.00 50.37 ? 115 PRO C C 1 ATOM 3454 O O . PRO C 1 115 ? 41.945 12.828 0.368 1.00 50.64 ? 115 PRO C O 1 ATOM 3455 C CB . PRO C 1 115 ? 41.192 15.796 1.440 1.00 49.40 ? 115 PRO C CB 1 ATOM 3456 C CG . PRO C 1 115 ? 41.703 16.440 0.213 1.00 49.18 ? 115 PRO C CG 1 ATOM 3457 C CD . PRO C 1 115 ? 43.183 16.358 0.278 1.00 49.60 ? 115 PRO C CD 1 ATOM 3458 N N . ALA C 1 116 ? 40.975 12.752 2.413 1.00 51.01 ? 116 ALA C N 1 ATOM 3459 C CA . ALA C 1 116 ? 40.421 11.410 2.254 1.00 51.58 ? 116 ALA C CA 1 ATOM 3460 C C . ALA C 1 116 ? 39.294 11.369 1.221 1.00 52.03 ? 116 ALA C C 1 ATOM 3461 O O . ALA C 1 116 ? 39.142 10.376 0.507 1.00 53.31 ? 116 ALA C O 1 ATOM 3462 C CB . ALA C 1 116 ? 39.945 10.866 3.601 1.00 51.49 ? 116 ALA C CB 1 ATOM 3463 N N . LEU C 1 117 ? 38.521 12.450 1.139 1.00 51.51 ? 117 LEU C N 1 ATOM 3464 C CA . LEU C 1 117 ? 37.410 12.543 0.198 1.00 52.70 ? 117 LEU C CA 1 ATOM 3465 C C . LEU C 1 117 ? 37.598 13.672 -0.823 1.00 52.92 ? 117 LEU C C 1 ATOM 3466 O O . LEU C 1 117 ? 38.036 14.765 -0.459 1.00 53.02 ? 117 LEU C O 1 ATOM 3467 C CB . LEU C 1 117 ? 36.086 12.706 0.950 1.00 54.34 ? 117 LEU C CB 1 ATOM 3468 C CG . LEU C 1 117 ? 35.704 11.569 1.912 1.00 55.12 ? 117 LEU C CG 1 ATOM 3469 C CD1 . LEU C 1 117 ? 34.577 11.998 2.853 1.00 55.49 ? 117 LEU C CD1 1 ATOM 3470 C CD2 . LEU C 1 117 ? 35.329 10.291 1.154 1.00 55.05 ? 117 LEU C CD2 1 ATOM 3471 N N . PRO C 1 118 ? 37.273 13.410 -2.110 1.00 52.67 ? 118 PRO C N 1 ATOM 3472 C CA . PRO C 1 118 ? 36.755 12.151 -2.665 1.00 51.93 ? 118 PRO C CA 1 ATOM 3473 C C . PRO C 1 118 ? 37.852 11.175 -3.068 1.00 50.98 ? 118 PRO C C 1 ATOM 3474 O O . PRO C 1 118 ? 37.558 10.103 -3.600 1.00 50.92 ? 118 PRO C O 1 ATOM 3475 C CB . PRO C 1 118 ? 36.021 12.618 -3.920 1.00 51.68 ? 118 PRO C CB 1 ATOM 3476 C CG . PRO C 1 118 ? 36.847 13.765 -4.399 1.00 52.29 ? 118 PRO C CG 1 ATOM 3477 C CD . PRO C 1 118 ? 37.396 14.445 -3.157 1.00 52.42 ? 118 PRO C CD 1 ATOM 3478 N N . PHE C 1 119 ? 39.100 11.539 -2.797 1.00 50.49 ? 119 PHE C N 1 ATOM 3479 C CA . PHE C 1 119 ? 40.251 10.833 -3.351 1.00 49.94 ? 119 PHE C CA 1 ATOM 3480 C C . PHE C 1 119 ? 40.344 9.344 -3.037 1.00 49.92 ? 119 PHE C C 1 ATOM 3481 O O . PHE C 1 119 ? 40.603 8.557 -3.942 1.00 48.03 ? 119 PHE C O 1 ATOM 3482 C CB . PHE C 1 119 ? 41.547 11.550 -2.998 1.00 49.15 ? 119 PHE C CB 1 ATOM 3483 C CG . PHE C 1 119 ? 41.607 12.953 -3.509 1.00 49.59 ? 119 PHE C CG 1 ATOM 3484 C CD1 . PHE C 1 119 ? 41.892 13.206 -4.849 1.00 49.76 ? 119 PHE C CD1 1 ATOM 3485 C CD2 . PHE C 1 119 ? 41.374 14.026 -2.657 1.00 48.61 ? 119 PHE C CD2 1 ATOM 3486 C CE1 . PHE C 1 119 ? 41.949 14.509 -5.324 1.00 49.74 ? 119 PHE C CE1 1 ATOM 3487 C CE2 . PHE C 1 119 ? 41.427 15.322 -3.128 1.00 49.08 ? 119 PHE C CE2 1 ATOM 3488 C CZ . PHE C 1 119 ? 41.714 15.567 -4.462 1.00 49.18 ? 119 PHE C CZ 1 ATOM 3489 N N . MET C 1 120 ? 40.127 8.949 -1.782 1.00 50.42 ? 120 MET C N 1 ATOM 3490 C CA . MET C 1 120 ? 40.238 7.525 -1.433 1.00 52.21 ? 120 MET C CA 1 ATOM 3491 C C . MET C 1 120 ? 39.257 6.681 -2.246 1.00 50.74 ? 120 MET C C 1 ATOM 3492 O O . MET C 1 120 ? 39.551 5.531 -2.580 1.00 50.30 ? 120 MET C O 1 ATOM 3493 C CB . MET C 1 120 ? 40.070 7.277 0.075 1.00 53.18 ? 120 MET C CB 1 ATOM 3494 C CG . MET C 1 120 ? 38.629 7.236 0.584 1.00 54.39 ? 120 MET C CG 1 ATOM 3495 S SD . MET C 1 120 ? 38.497 6.930 2.362 1.00 56.14 ? 120 MET C SD 1 ATOM 3496 C CE . MET C 1 120 ? 39.114 5.249 2.477 1.00 56.26 ? 120 MET C CE 1 ATOM 3497 N N . LEU C 1 121 ? 38.113 7.281 -2.581 1.00 49.16 ? 121 LEU C N 1 ATOM 3498 C CA . LEU C 1 121 ? 37.062 6.614 -3.343 1.00 48.91 ? 121 LEU C CA 1 ATOM 3499 C C . LEU C 1 121 ? 37.212 6.659 -4.880 1.00 48.05 ? 121 LEU C C 1 ATOM 3500 O O . LEU C 1 121 ? 36.329 6.183 -5.604 1.00 48.68 ? 121 LEU C O 1 ATOM 3501 C CB . LEU C 1 121 ? 35.691 7.149 -2.922 1.00 50.65 ? 121 LEU C CB 1 ATOM 3502 C CG . LEU C 1 121 ? 35.169 6.804 -1.520 1.00 51.69 ? 121 LEU C CG 1 ATOM 3503 C CD1 . LEU C 1 121 ? 33.697 7.217 -1.415 1.00 51.78 ? 121 LEU C CD1 1 ATOM 3504 C CD2 . LEU C 1 121 ? 35.335 5.311 -1.178 1.00 51.51 ? 121 LEU C CD2 1 ATOM 3505 N N . ALA C 1 122 ? 38.315 7.233 -5.368 1.00 44.95 ? 122 ALA C N 1 ATOM 3506 C CA . ALA C 1 122 ? 38.651 7.202 -6.785 1.00 42.16 ? 122 ALA C CA 1 ATOM 3507 C C . ALA C 1 122 ? 39.161 5.816 -7.183 1.00 40.79 ? 122 ALA C C 1 ATOM 3508 O O . ALA C 1 122 ? 39.911 5.193 -6.425 1.00 42.10 ? 122 ALA C O 1 ATOM 3509 C CB . ALA C 1 122 ? 39.685 8.268 -7.113 1.00 41.28 ? 122 ALA C CB 1 ATOM 3510 N N . GLU C 1 123 ? 38.740 5.338 -8.356 1.00 37.19 ? 123 GLU C N 1 ATOM 3511 C CA . GLU C 1 123 ? 39.200 4.054 -8.912 1.00 37.06 ? 123 GLU C CA 1 ATOM 3512 C C . GLU C 1 123 ? 40.580 4.169 -9.538 1.00 35.54 ? 123 GLU C C 1 ATOM 3513 O O . GLU C 1 123 ? 41.302 3.185 -9.672 1.00 37.74 ? 123 GLU C O 1 ATOM 3514 C CB . GLU C 1 123 ? 38.244 3.551 -9.998 1.00 38.85 ? 123 GLU C CB 1 ATOM 3515 C CG . GLU C 1 123 ? 36.913 3.040 -9.508 1.00 42.12 ? 123 GLU C CG 1 ATOM 3516 C CD . GLU C 1 123 ? 37.048 1.892 -8.521 1.00 45.22 ? 123 GLU C CD 1 ATOM 3517 O OE1 . GLU C 1 123 ? 37.581 0.814 -8.906 1.00 45.40 ? 123 GLU C OE1 1 ATOM 3518 O OE2 . GLU C 1 123 ? 36.620 2.091 -7.358 1.00 46.39 ? 123 GLU C OE2 1 ATOM 3519 N N . PHE C 1 124 ? 40.921 5.378 -9.953 1.00 33.44 ? 124 PHE C N 1 ATOM 3520 C CA . PHE C 1 124 ? 42.194 5.675 -10.610 1.00 32.63 ? 124 PHE C CA 1 ATOM 3521 C C . PHE C 1 124 ? 43.209 6.175 -9.581 1.00 31.93 ? 124 PHE C C 1 ATOM 3522 O O . PHE C 1 124 ? 42.831 6.640 -8.503 1.00 31.55 ? 124 PHE C O 1 ATOM 3523 C CB . PHE C 1 124 ? 41.967 6.752 -11.677 1.00 29.57 ? 124 PHE C CB 1 ATOM 3524 C CG . PHE C 1 124 ? 41.191 7.949 -11.170 1.00 27.66 ? 124 PHE C CG 1 ATOM 3525 C CD1 . PHE C 1 124 ? 39.793 7.922 -11.127 1.00 26.52 ? 124 PHE C CD1 1 ATOM 3526 C CD2 . PHE C 1 124 ? 41.859 9.091 -10.727 1.00 26.98 ? 124 PHE C CD2 1 ATOM 3527 C CE1 . PHE C 1 124 ? 39.072 9.022 -10.662 1.00 27.64 ? 124 PHE C CE1 1 ATOM 3528 C CE2 . PHE C 1 124 ? 41.145 10.207 -10.246 1.00 27.30 ? 124 PHE C CE2 1 ATOM 3529 C CZ . PHE C 1 124 ? 39.753 10.176 -10.222 1.00 27.16 ? 124 PHE C CZ 1 ATOM 3530 N N . ASP C 1 125 ? 44.490 6.100 -9.922 1.00 32.06 ? 125 ASP C N 1 ATOM 3531 C CA . ASP C 1 125 ? 45.549 6.513 -9.002 1.00 34.20 ? 125 ASP C CA 1 ATOM 3532 C C . ASP C 1 125 ? 45.956 7.968 -9.148 1.00 34.18 ? 125 ASP C C 1 ATOM 3533 O O . ASP C 1 125 ? 46.494 8.548 -8.214 1.00 35.04 ? 125 ASP C O 1 ATOM 3534 C CB . ASP C 1 125 ? 46.761 5.591 -9.125 1.00 34.68 ? 125 ASP C CB 1 ATOM 3535 C CG . ASP C 1 125 ? 46.367 4.134 -9.143 1.00 35.38 ? 125 ASP C CG 1 ATOM 3536 O OD1 . ASP C 1 125 ? 45.794 3.668 -8.133 1.00 36.13 ? 125 ASP C OD1 1 ATOM 3537 O OD2 . ASP C 1 125 ? 46.609 3.465 -10.172 1.00 34.41 ? 125 ASP C OD2 1 ATOM 3538 N N . GLY C 1 126 ? 45.684 8.573 -10.300 1.00 34.43 ? 126 GLY C N 1 ATOM 3539 C CA . GLY C 1 126 ? 46.075 9.959 -10.503 1.00 32.86 ? 126 GLY C CA 1 ATOM 3540 C C . GLY C 1 126 ? 45.466 10.658 -11.692 1.00 33.07 ? 126 GLY C C 1 ATOM 3541 O O . GLY C 1 126 ? 44.398 10.292 -12.168 1.00 34.52 ? 126 GLY C O 1 ATOM 3542 N N . VAL C 1 127 ? 46.159 11.687 -12.161 1.00 32.42 ? 127 VAL C N 1 ATOM 3543 C CA . VAL C 1 127 ? 45.584 12.647 -13.084 1.00 33.43 ? 127 VAL C CA 1 ATOM 3544 C C . VAL C 1 127 ? 46.630 13.115 -14.063 1.00 32.24 ? 127 VAL C C 1 ATOM 3545 O O . VAL C 1 127 ? 47.771 13.395 -13.684 1.00 33.45 ? 127 VAL C O 1 ATOM 3546 C CB . VAL C 1 127 ? 45.009 13.889 -12.342 1.00 34.39 ? 127 VAL C CB 1 ATOM 3547 C CG1 . VAL C 1 127 ? 44.228 14.775 -13.289 1.00 33.77 ? 127 VAL C CG1 1 ATOM 3548 C CG2 . VAL C 1 127 ? 44.094 13.457 -11.239 1.00 36.70 ? 127 VAL C CG2 1 ATOM 3549 N N . VAL C 1 128 ? 46.221 13.190 -15.322 1.00 31.15 ? 128 VAL C N 1 ATOM 3550 C CA . VAL C 1 128 ? 47.004 13.813 -16.381 1.00 30.03 ? 128 VAL C CA 1 ATOM 3551 C C . VAL C 1 128 ? 46.211 15.036 -16.824 1.00 30.64 ? 128 VAL C C 1 ATOM 3552 O O . VAL C 1 128 ? 45.113 14.916 -17.373 1.00 30.13 ? 128 VAL C O 1 ATOM 3553 C CB . VAL C 1 128 ? 47.238 12.839 -17.567 1.00 30.27 ? 128 VAL C CB 1 ATOM 3554 C CG1 . VAL C 1 128 ? 47.960 13.521 -18.734 1.00 30.64 ? 128 VAL C CG1 1 ATOM 3555 C CG2 . VAL C 1 128 ? 48.015 11.622 -17.110 1.00 29.40 ? 128 VAL C CG2 1 ATOM 3556 N N . GLY C 1 129 ? 46.742 16.216 -16.524 1.00 31.00 ? 129 GLY C N 1 ATOM 3557 C CA . GLY C 1 129 ? 46.124 17.463 -16.957 1.00 31.74 ? 129 GLY C CA 1 ATOM 3558 C C . GLY C 1 129 ? 46.379 17.737 -18.431 1.00 32.17 ? 129 GLY C C 1 ATOM 3559 O O . GLY C 1 129 ? 47.527 17.724 -18.870 1.00 31.36 ? 129 GLY C O 1 ATOM 3560 N N . MET C 1 130 ? 45.300 17.985 -19.180 1.00 32.90 ? 130 MET C N 1 ATOM 3561 C CA . MET C 1 130 ? 45.343 18.237 -20.632 1.00 33.62 ? 130 MET C CA 1 ATOM 3562 C C . MET C 1 130 ? 45.014 19.706 -20.931 1.00 34.16 ? 130 MET C C 1 ATOM 3563 O O . MET C 1 130 ? 44.743 20.087 -22.090 1.00 32.56 ? 130 MET C O 1 ATOM 3564 C CB . MET C 1 130 ? 44.335 17.343 -21.369 1.00 35.05 ? 130 MET C CB 1 ATOM 3565 C CG . MET C 1 130 ? 44.510 15.849 -21.162 1.00 36.54 ? 130 MET C CG 1 ATOM 3566 S SD . MET C 1 130 ? 46.067 15.251 -21.836 1.00 39.48 ? 130 MET C SD 1 ATOM 3567 C CE . MET C 1 130 ? 45.713 15.123 -23.587 1.00 38.72 ? 130 MET C CE 1 ATOM 3568 N N . GLY C 1 131 ? 45.016 20.520 -19.877 1.00 31.93 ? 131 GLY C N 1 ATOM 3569 C CA . GLY C 1 131 ? 44.786 21.950 -20.004 1.00 32.68 ? 131 GLY C CA 1 ATOM 3570 C C . GLY C 1 131 ? 46.056 22.643 -20.438 1.00 34.71 ? 131 GLY C C 1 ATOM 3571 O O . GLY C 1 131 ? 47.052 21.995 -20.767 1.00 34.42 ? 131 GLY C O 1 ATOM 3572 N N . PHE C 1 132 ? 46.021 23.969 -20.430 1.00 36.65 ? 132 PHE C N 1 ATOM 3573 C CA . PHE C 1 132 ? 47.123 24.786 -20.927 1.00 37.40 ? 132 PHE C CA 1 ATOM 3574 C C . PHE C 1 132 ? 48.144 25.102 -19.845 1.00 39.33 ? 132 PHE C C 1 ATOM 3575 O O . PHE C 1 132 ? 47.834 25.069 -18.656 1.00 39.06 ? 132 PHE C O 1 ATOM 3576 C CB . PHE C 1 132 ? 46.569 26.103 -21.461 1.00 38.99 ? 132 PHE C CB 1 ATOM 3577 C CG . PHE C 1 132 ? 45.765 25.970 -22.713 1.00 38.18 ? 132 PHE C CG 1 ATOM 3578 C CD1 . PHE C 1 132 ? 44.429 25.599 -22.662 1.00 38.02 ? 132 PHE C CD1 1 ATOM 3579 C CD2 . PHE C 1 132 ? 46.342 26.236 -23.948 1.00 37.99 ? 132 PHE C CD2 1 ATOM 3580 C CE1 . PHE C 1 132 ? 43.678 25.489 -23.833 1.00 38.35 ? 132 PHE C CE1 1 ATOM 3581 C CE2 . PHE C 1 132 ? 45.603 26.132 -25.116 1.00 38.40 ? 132 PHE C CE2 1 ATOM 3582 C CZ . PHE C 1 132 ? 44.270 25.752 -25.061 1.00 38.16 ? 132 PHE C CZ 1 ATOM 3583 N N . ILE C 1 133 ? 49.354 25.454 -20.263 1.00 42.36 ? 133 ILE C N 1 ATOM 3584 C CA . ILE C 1 133 ? 50.422 25.818 -19.323 1.00 44.89 ? 133 ILE C CA 1 ATOM 3585 C C . ILE C 1 133 ? 50.088 27.043 -18.466 1.00 47.15 ? 133 ILE C C 1 ATOM 3586 O O . ILE C 1 133 ? 50.616 27.188 -17.360 1.00 49.42 ? 133 ILE C O 1 ATOM 3587 C CB . ILE C 1 133 ? 51.798 25.978 -20.026 1.00 44.45 ? 133 ILE C CB 1 ATOM 3588 C CG1 . ILE C 1 133 ? 52.908 26.129 -18.982 1.00 44.48 ? 133 ILE C CG1 1 ATOM 3589 C CG2 . ILE C 1 133 ? 51.778 27.119 -21.053 1.00 43.67 ? 133 ILE C CG2 1 ATOM 3590 C CD1 . ILE C 1 133 ? 54.293 25.803 -19.501 1.00 45.51 ? 133 ILE C CD1 1 ATOM 3591 N N . GLU C 1 134 ? 49.196 27.900 -18.967 1.00 47.47 ? 134 GLU C N 1 ATOM 3592 C CA . GLU C 1 134 ? 48.750 29.091 -18.239 1.00 48.40 ? 134 GLU C CA 1 ATOM 3593 C C . GLU C 1 134 ? 48.040 28.750 -16.933 1.00 48.12 ? 134 GLU C C 1 ATOM 3594 O O . GLU C 1 134 ? 47.773 29.631 -16.111 1.00 49.02 ? 134 GLU C O 1 ATOM 3595 C CB . GLU C 1 134 ? 47.832 29.953 -19.115 1.00 49.13 ? 134 GLU C CB 1 ATOM 3596 C CG . GLU C 1 134 ? 48.531 30.670 -20.271 1.00 50.89 ? 134 GLU C CG 1 ATOM 3597 C CD . GLU C 1 134 ? 48.440 29.928 -21.599 1.00 51.78 ? 134 GLU C CD 1 ATOM 3598 O OE1 . GLU C 1 134 ? 48.447 28.679 -21.604 1.00 52.69 ? 134 GLU C OE1 1 ATOM 3599 O OE2 . GLU C 1 134 ? 48.365 30.600 -22.649 1.00 51.78 ? 134 GLU C OE2 1 ATOM 3600 N N . GLN C 1 135 ? 47.729 27.472 -16.744 1.00 47.88 ? 135 GLN C N 1 ATOM 3601 C CA . GLN C 1 135 ? 46.990 27.028 -15.561 1.00 47.71 ? 135 GLN C CA 1 ATOM 3602 C C . GLN C 1 135 ? 47.734 25.919 -14.833 1.00 44.84 ? 135 GLN C C 1 ATOM 3603 O O . GLN C 1 135 ? 47.232 25.365 -13.858 1.00 43.70 ? 135 GLN C O 1 ATOM 3604 C CB . GLN C 1 135 ? 45.579 26.561 -15.939 1.00 49.76 ? 135 GLN C CB 1 ATOM 3605 C CG . GLN C 1 135 ? 44.766 27.569 -16.739 1.00 53.06 ? 135 GLN C CG 1 ATOM 3606 C CD . GLN C 1 135 ? 43.623 28.179 -15.951 1.00 54.93 ? 135 GLN C CD 1 ATOM 3607 O OE1 . GLN C 1 135 ? 43.738 29.292 -15.424 1.00 55.81 ? 135 GLN C OE1 1 ATOM 3608 N NE2 . GLN C 1 135 ? 42.506 27.452 -15.865 1.00 54.27 ? 135 GLN C NE2 1 ATOM 3609 N N . ALA C 1 136 ? 48.928 25.597 -15.321 1.00 44.56 ? 136 ALA C N 1 ATOM 3610 C CA . ALA C 1 136 ? 49.776 24.594 -14.692 1.00 44.49 ? 136 ALA C CA 1 ATOM 3611 C C . ALA C 1 136 ? 50.350 25.149 -13.401 1.00 45.32 ? 136 ALA C C 1 ATOM 3612 O O . ALA C 1 136 ? 50.947 26.227 -13.392 1.00 44.66 ? 136 ALA C O 1 ATOM 3613 C CB . ALA C 1 136 ? 50.887 24.182 -15.625 1.00 43.43 ? 136 ALA C CB 1 ATOM 3614 N N . ILE C 1 137 ? 50.151 24.412 -12.313 1.00 47.26 ? 137 ILE C N 1 ATOM 3615 C CA . ILE C 1 137 ? 50.717 24.776 -11.018 1.00 47.72 ? 137 ILE C CA 1 ATOM 3616 C C . ILE C 1 137 ? 52.238 24.692 -11.099 1.00 48.98 ? 137 ILE C C 1 ATOM 3617 O O . ILE C 1 137 ? 52.782 23.696 -11.576 1.00 50.64 ? 137 ILE C O 1 ATOM 3618 C CB . ILE C 1 137 ? 50.146 23.894 -9.878 1.00 47.32 ? 137 ILE C CB 1 ATOM 3619 C CG1 . ILE C 1 137 ? 48.640 24.171 -9.728 1.00 46.69 ? 137 ILE C CG1 1 ATOM 3620 C CG2 . ILE C 1 137 ? 50.902 24.145 -8.555 1.00 46.93 ? 137 ILE C CG2 1 ATOM 3621 C CD1 . ILE C 1 137 ? 47.907 23.238 -8.791 1.00 46.28 ? 137 ILE C CD1 1 ATOM 3622 N N . GLY C 1 138 ? 52.910 25.759 -10.666 1.00 49.17 ? 138 GLY C N 1 ATOM 3623 C CA . GLY C 1 138 ? 54.373 25.855 -10.744 1.00 49.19 ? 138 GLY C CA 1 ATOM 3624 C C . GLY C 1 138 ? 54.881 26.086 -12.155 1.00 49.59 ? 138 GLY C C 1 ATOM 3625 O O . GLY C 1 138 ? 56.069 25.894 -12.435 1.00 48.57 ? 138 GLY C O 1 ATOM 3626 N N . ARG C 1 139 ? 53.966 26.506 -13.033 1.00 50.24 ? 139 ARG C N 1 ATOM 3627 C CA . ARG C 1 139 ? 54.196 26.667 -14.477 1.00 50.85 ? 139 ARG C CA 1 ATOM 3628 C C . ARG C 1 139 ? 54.960 25.516 -15.166 1.00 48.73 ? 139 ARG C C 1 ATOM 3629 O O . ARG C 1 139 ? 55.764 25.733 -16.081 1.00 50.18 ? 139 ARG C O 1 ATOM 3630 C CB . ARG C 1 139 ? 54.787 28.046 -14.805 1.00 53.71 ? 139 ARG C CB 1 ATOM 3631 C CG . ARG C 1 139 ? 54.488 28.473 -16.242 1.00 57.92 ? 139 ARG C CG 1 ATOM 3632 C CD . ARG C 1 139 ? 54.390 29.981 -16.416 1.00 60.91 ? 139 ARG C CD 1 ATOM 3633 N NE . ARG C 1 139 ? 54.475 30.350 -17.834 1.00 63.37 ? 139 ARG C NE 1 ATOM 3634 C CZ . ARG C 1 139 ? 53.434 30.459 -18.658 1.00 64.34 ? 139 ARG C CZ 1 ATOM 3635 N NH1 . ARG C 1 139 ? 52.199 30.234 -18.216 1.00 64.62 ? 139 ARG C NH1 1 ATOM 3636 N NH2 . ARG C 1 139 ? 53.630 30.799 -19.929 1.00 64.29 ? 139 ARG C NH2 1 ATOM 3637 N N . VAL C 1 140 ? 54.685 24.293 -14.728 1.00 45.38 ? 140 VAL C N 1 ATOM 3638 C CA . VAL C 1 140 ? 55.258 23.093 -15.337 1.00 43.67 ? 140 VAL C CA 1 ATOM 3639 C C . VAL C 1 140 ? 54.685 22.860 -16.749 1.00 42.56 ? 140 VAL C C 1 ATOM 3640 O O . VAL C 1 140 ? 53.498 23.071 -16.994 1.00 41.86 ? 140 VAL C O 1 ATOM 3641 C CB . VAL C 1 140 ? 54.996 21.843 -14.451 1.00 43.32 ? 140 VAL C CB 1 ATOM 3642 C CG1 . VAL C 1 140 ? 55.668 20.605 -15.033 1.00 42.83 ? 140 VAL C CG1 1 ATOM 3643 C CG2 . VAL C 1 140 ? 55.470 22.090 -13.023 1.00 43.26 ? 140 VAL C CG2 1 ATOM 3644 N N . THR C 1 141 ? 55.535 22.416 -17.669 1.00 40.89 ? 141 THR C N 1 ATOM 3645 C CA . THR C 1 141 ? 55.103 22.133 -19.032 1.00 39.08 ? 141 THR C CA 1 ATOM 3646 C C . THR C 1 141 ? 54.218 20.889 -19.084 1.00 37.66 ? 141 THR C C 1 ATOM 3647 O O . THR C 1 141 ? 54.690 19.781 -18.788 1.00 38.25 ? 141 THR C O 1 ATOM 3648 C CB . THR C 1 141 ? 56.294 21.997 -19.992 1.00 38.79 ? 141 THR C CB 1 ATOM 3649 O OG1 . THR C 1 141 ? 57.038 23.220 -19.996 1.00 38.84 ? 141 THR C OG1 1 ATOM 3650 C CG2 . THR C 1 141 ? 55.808 21.715 -21.412 1.00 39.57 ? 141 THR C CG2 1 ATOM 3651 N N . PRO C 1 142 ? 52.932 21.065 -19.464 1.00 36.09 ? 142 PRO C N 1 ATOM 3652 C CA . PRO C 1 142 ? 51.999 19.935 -19.469 1.00 35.53 ? 142 PRO C CA 1 ATOM 3653 C C . PRO C 1 142 ? 52.419 18.878 -20.484 1.00 35.39 ? 142 PRO C C 1 ATOM 3654 O O . PRO C 1 142 ? 53.112 19.188 -21.455 1.00 36.45 ? 142 PRO C O 1 ATOM 3655 C CB . PRO C 1 142 ? 50.664 20.583 -19.851 1.00 34.80 ? 142 PRO C CB 1 ATOM 3656 C CG . PRO C 1 142 ? 50.847 22.044 -19.515 1.00 36.02 ? 142 PRO C CG 1 ATOM 3657 C CD . PRO C 1 142 ? 52.266 22.300 -19.911 1.00 35.38 ? 142 PRO C CD 1 ATOM 3658 N N . ILE C 1 143 ? 52.011 17.639 -20.245 1.00 35.11 ? 143 ILE C N 1 ATOM 3659 C CA . ILE C 1 143 ? 52.480 16.504 -21.039 1.00 34.54 ? 143 ILE C CA 1 ATOM 3660 C C . ILE C 1 143 ? 52.175 16.638 -22.533 1.00 33.04 ? 143 ILE C C 1 ATOM 3661 O O . ILE C 1 143 ? 52.998 16.250 -23.373 1.00 32.22 ? 143 ILE C O 1 ATOM 3662 C CB . ILE C 1 143 ? 51.955 15.159 -20.476 1.00 34.77 ? 143 ILE C CB 1 ATOM 3663 C CG1 . ILE C 1 143 ? 52.782 13.986 -21.005 1.00 35.22 ? 143 ILE C CG1 1 ATOM 3664 C CG2 . ILE C 1 143 ? 50.471 14.988 -20.772 1.00 36.22 ? 143 ILE C CG2 1 ATOM 3665 C CD1 . ILE C 1 143 ? 52.590 12.707 -20.210 1.00 35.86 ? 143 ILE C CD1 1 ATOM 3666 N N . PHE C 1 144 ? 51.007 17.183 -22.864 1.00 32.35 ? 144 PHE C N 1 ATOM 3667 C CA . PHE C 1 144 ? 50.638 17.337 -24.276 1.00 33.65 ? 144 PHE C CA 1 ATOM 3668 C C . PHE C 1 144 ? 51.574 18.282 -25.040 1.00 34.70 ? 144 PHE C C 1 ATOM 3669 O O . PHE C 1 144 ? 51.924 17.998 -26.189 1.00 35.33 ? 144 PHE C O 1 ATOM 3670 C CB . PHE C 1 144 ? 49.157 17.705 -24.490 1.00 31.56 ? 144 PHE C CB 1 ATOM 3671 C CG . PHE C 1 144 ? 48.705 17.520 -25.919 1.00 32.22 ? 144 PHE C CG 1 ATOM 3672 C CD1 . PHE C 1 144 ? 48.647 16.246 -26.482 1.00 31.08 ? 144 PHE C CD1 1 ATOM 3673 C CD2 . PHE C 1 144 ? 48.388 18.622 -26.720 1.00 32.09 ? 144 PHE C CD2 1 ATOM 3674 C CE1 . PHE C 1 144 ? 48.265 16.070 -27.811 1.00 31.88 ? 144 PHE C CE1 1 ATOM 3675 C CE2 . PHE C 1 144 ? 47.999 18.455 -28.057 1.00 30.96 ? 144 PHE C CE2 1 ATOM 3676 C CZ . PHE C 1 144 ? 47.935 17.184 -28.602 1.00 31.53 ? 144 PHE C CZ 1 ATOM 3677 N N . ASP C 1 145 ? 51.976 19.382 -24.396 1.00 36.15 ? 145 ASP C N 1 ATOM 3678 C CA . ASP C 1 145 ? 52.940 20.336 -24.968 1.00 39.56 ? 145 ASP C CA 1 ATOM 3679 C C . ASP C 1 145 ? 54.268 19.669 -25.294 1.00 40.44 ? 145 ASP C C 1 ATOM 3680 O O . ASP C 1 145 ? 54.808 19.848 -26.394 1.00 41.41 ? 145 ASP C O 1 ATOM 3681 C CB . ASP C 1 145 ? 53.195 21.500 -24.013 1.00 41.68 ? 145 ASP C CB 1 ATOM 3682 C CG . ASP C 1 145 ? 51.950 22.297 -23.718 1.00 42.91 ? 145 ASP C CG 1 ATOM 3683 O OD1 . ASP C 1 145 ? 50.936 21.690 -23.303 1.00 45.42 ? 145 ASP C OD1 1 ATOM 3684 O OD2 . ASP C 1 145 ? 51.989 23.531 -23.885 1.00 41.76 ? 145 ASP C OD2 1 ATOM 3685 N N . ASN C 1 146 ? 54.786 18.901 -24.335 1.00 39.61 ? 146 ASN C N 1 ATOM 3686 C CA . ASN C 1 146 ? 55.989 18.113 -24.538 1.00 38.95 ? 146 ASN C CA 1 ATOM 3687 C C . ASN C 1 146 ? 55.839 17.098 -25.666 1.00 39.81 ? 146 ASN C C 1 ATOM 3688 O O . ASN C 1 146 ? 56.807 16.811 -26.371 1.00 41.92 ? 146 ASN C O 1 ATOM 3689 C CB . ASN C 1 146 ? 56.399 17.400 -23.244 1.00 40.38 ? 146 ASN C CB 1 ATOM 3690 C CG . ASN C 1 146 ? 56.995 18.344 -22.204 1.00 41.67 ? 146 ASN C CG 1 ATOM 3691 O OD1 . ASN C 1 146 ? 57.594 19.376 -22.539 1.00 43.60 ? 146 ASN C OD1 1 ATOM 3692 N ND2 . ASN C 1 146 ? 56.836 17.991 -20.933 1.00 39.38 ? 146 ASN C ND2 1 ATOM 3693 N N . ILE C 1 147 ? 54.639 16.537 -25.828 1.00 39.29 ? 147 ILE C N 1 ATOM 3694 C CA . ILE C 1 147 ? 54.392 15.578 -26.916 1.00 38.40 ? 147 ILE C CA 1 ATOM 3695 C C . ILE C 1 147 ? 54.304 16.321 -28.263 1.00 38.50 ? 147 ILE C C 1 ATOM 3696 O O . ILE C 1 147 ? 54.789 15.818 -29.279 1.00 37.75 ? 147 ILE C O 1 ATOM 3697 C CB . ILE C 1 147 ? 53.146 14.678 -26.655 1.00 38.00 ? 147 ILE C CB 1 ATOM 3698 C CG1 . ILE C 1 147 ? 53.406 13.712 -25.487 1.00 38.74 ? 147 ILE C CG1 1 ATOM 3699 C CG2 . ILE C 1 147 ? 52.761 13.887 -27.904 1.00 36.32 ? 147 ILE C CG2 1 ATOM 3700 C CD1 . ILE C 1 147 ? 52.166 12.905 -25.035 1.00 37.56 ? 147 ILE C CD1 1 ATOM 3701 N N . ILE C 1 148 ? 53.705 17.515 -28.250 1.00 38.26 ? 148 ILE C N 1 ATOM 3702 C CA . ILE C 1 148 ? 53.696 18.410 -29.416 1.00 40.07 ? 148 ILE C CA 1 ATOM 3703 C C . ILE C 1 148 ? 55.125 18.693 -29.873 1.00 42.09 ? 148 ILE C C 1 ATOM 3704 O O . ILE C 1 148 ? 55.423 18.622 -31.074 1.00 43.67 ? 148 ILE C O 1 ATOM 3705 C CB . ILE C 1 148 ? 52.959 19.757 -29.119 1.00 40.01 ? 148 ILE C CB 1 ATOM 3706 C CG1 . ILE C 1 148 ? 51.438 19.569 -29.164 1.00 39.87 ? 148 ILE C CG1 1 ATOM 3707 C CG2 . ILE C 1 148 ? 53.394 20.873 -30.086 1.00 38.90 ? 148 ILE C CG2 1 ATOM 3708 C CD1 . ILE C 1 148 ? 50.650 20.815 -28.719 1.00 39.64 ? 148 ILE C CD1 1 ATOM 3709 N N . SER C 1 149 ? 56.005 18.974 -28.905 1.00 42.65 ? 149 SER C N 1 ATOM 3710 C CA . SER C 1 149 ? 57.387 19.371 -29.172 1.00 42.03 ? 149 SER C CA 1 ATOM 3711 C C . SER C 1 149 ? 58.189 18.328 -29.937 1.00 41.11 ? 149 SER C C 1 ATOM 3712 O O . SER C 1 149 ? 59.154 18.673 -30.618 1.00 41.23 ? 149 SER C O 1 ATOM 3713 C CB . SER C 1 149 ? 58.115 19.743 -27.872 1.00 43.87 ? 149 SER C CB 1 ATOM 3714 O OG . SER C 1 149 ? 57.857 21.100 -27.507 1.00 45.52 ? 149 SER C OG 1 ATOM 3715 N N . GLN C 1 150 ? 57.786 17.065 -29.829 1.00 39.38 ? 150 GLN C N 1 ATOM 3716 C CA . GLN C 1 150 ? 58.520 15.960 -30.445 1.00 39.29 ? 150 GLN C CA 1 ATOM 3717 C C . GLN C 1 150 ? 58.243 15.880 -31.941 1.00 38.77 ? 150 GLN C C 1 ATOM 3718 O O . GLN C 1 150 ? 58.890 15.105 -32.651 1.00 38.04 ? 150 GLN C O 1 ATOM 3719 C CB . GLN C 1 150 ? 58.164 14.616 -29.784 1.00 37.28 ? 150 GLN C CB 1 ATOM 3720 C CG . GLN C 1 150 ? 58.502 14.545 -28.311 1.00 38.93 ? 150 GLN C CG 1 ATOM 3721 C CD . GLN C 1 150 ? 58.098 13.230 -27.644 1.00 39.63 ? 150 GLN C CD 1 ATOM 3722 O OE1 . GLN C 1 150 ? 57.767 13.217 -26.459 1.00 41.24 ? 150 GLN C OE1 1 ATOM 3723 N NE2 . GLN C 1 150 ? 58.128 12.127 -28.395 1.00 37.72 ? 150 GLN C NE2 1 ATOM 3724 N N . GLY C 1 151 ? 57.262 16.662 -32.394 1.00 39.01 ? 151 GLY C N 1 ATOM 3725 C CA . GLY C 1 151 ? 56.793 16.655 -33.782 1.00 39.25 ? 151 GLY C CA 1 ATOM 3726 C C . GLY C 1 151 ? 56.354 15.295 -34.295 1.00 40.59 ? 151 GLY C C 1 ATOM 3727 O O . GLY C 1 151 ? 56.506 14.996 -35.479 1.00 43.04 ? 151 GLY C O 1 ATOM 3728 N N . VAL C 1 152 ? 55.795 14.472 -33.412 1.00 39.89 ? 152 VAL C N 1 ATOM 3729 C CA . VAL C 1 152 ? 55.383 13.109 -33.768 1.00 39.18 ? 152 VAL C CA 1 ATOM 3730 C C . VAL C 1 152 ? 53.942 13.000 -34.304 1.00 37.96 ? 152 VAL C C 1 ATOM 3731 O O . VAL C 1 152 ? 53.647 12.158 -35.159 1.00 38.50 ? 152 VAL C O 1 ATOM 3732 C CB . VAL C 1 152 ? 55.571 12.120 -32.564 1.00 39.39 ? 152 VAL C CB 1 ATOM 3733 C CG1 . VAL C 1 152 ? 57.063 11.807 -32.347 1.00 38.10 ? 152 VAL C CG1 1 ATOM 3734 C CG2 . VAL C 1 152 ? 54.911 12.669 -31.264 1.00 37.74 ? 152 VAL C CG2 1 ATOM 3735 N N . LEU C 1 153 ? 53.054 13.849 -33.803 1.00 34.69 ? 153 LEU C N 1 ATOM 3736 C CA . LEU C 1 153 ? 51.626 13.720 -34.093 1.00 34.92 ? 153 LEU C CA 1 ATOM 3737 C C . LEU C 1 153 ? 51.192 14.418 -35.396 1.00 34.39 ? 153 LEU C C 1 ATOM 3738 O O . LEU C 1 153 ? 51.624 15.523 -35.676 1.00 33.99 ? 153 LEU C O 1 ATOM 3739 C CB . LEU C 1 153 ? 50.795 14.222 -32.892 1.00 33.22 ? 153 LEU C CB 1 ATOM 3740 C CG . LEU C 1 153 ? 51.021 13.582 -31.504 1.00 32.14 ? 153 LEU C CG 1 ATOM 3741 C CD1 . LEU C 1 153 ? 50.005 14.064 -30.483 1.00 30.52 ? 153 LEU C CD1 1 ATOM 3742 C CD2 . LEU C 1 153 ? 51.014 12.060 -31.575 1.00 31.55 ? 153 LEU C CD2 1 ATOM 3743 N N . LYS C 1 154 ? 50.343 13.746 -36.175 1.00 34.96 ? 154 LYS C N 1 ATOM 3744 C CA . LYS C 1 154 ? 49.663 14.319 -37.346 1.00 36.90 ? 154 LYS C CA 1 ATOM 3745 C C . LYS C 1 154 ? 49.198 15.759 -37.105 1.00 37.86 ? 154 LYS C C 1 ATOM 3746 O O . LYS C 1 154 ? 49.508 16.654 -37.893 1.00 38.49 ? 154 LYS C O 1 ATOM 3747 C CB . LYS C 1 154 ? 48.461 13.440 -37.719 1.00 38.05 ? 154 LYS C CB 1 ATOM 3748 C CG . LYS C 1 154 ? 47.901 13.585 -39.131 1.00 39.64 ? 154 LYS C CG 1 ATOM 3749 C CD . LYS C 1 154 ? 46.647 12.710 -39.267 1.00 41.08 ? 154 LYS C CD 1 ATOM 3750 C CE . LYS C 1 154 ? 46.260 12.322 -40.711 1.00 44.89 ? 154 LYS C CE 1 ATOM 3751 N NZ . LYS C 1 154 ? 46.143 13.424 -41.725 1.00 46.25 ? 154 LYS C NZ 1 ATOM 3752 N N . GLU C 1 155 ? 48.460 15.978 -36.014 1.00 37.85 ? 155 GLU C N 1 ATOM 3753 C CA . GLU C 1 155 ? 47.902 17.287 -35.697 1.00 38.48 ? 155 GLU C CA 1 ATOM 3754 C C . GLU C 1 155 ? 48.120 17.654 -34.233 1.00 35.23 ? 155 GLU C C 1 ATOM 3755 O O . GLU C 1 155 ? 48.341 16.776 -33.391 1.00 34.98 ? 155 GLU C O 1 ATOM 3756 C CB . GLU C 1 155 ? 46.401 17.315 -36.011 1.00 40.65 ? 155 GLU C CB 1 ATOM 3757 C CG . GLU C 1 155 ? 46.041 17.327 -37.483 1.00 43.56 ? 155 GLU C CG 1 ATOM 3758 C CD . GLU C 1 155 ? 44.565 17.657 -37.745 1.00 46.72 ? 155 GLU C CD 1 ATOM 3759 O OE1 . GLU C 1 155 ? 43.716 17.540 -36.820 1.00 48.05 ? 155 GLU C OE1 1 ATOM 3760 O OE2 . GLU C 1 155 ? 44.247 18.030 -38.905 1.00 51.78 ? 155 GLU C OE2 1 ATOM 3761 N N . ASP C 1 156 ? 48.050 18.950 -33.930 1.00 31.83 ? 156 ASP C N 1 ATOM 3762 C CA . ASP C 1 156 ? 48.057 19.420 -32.545 1.00 31.14 ? 156 ASP C CA 1 ATOM 3763 C C . ASP C 1 156 ? 46.651 19.381 -31.958 1.00 28.09 ? 156 ASP C C 1 ATOM 3764 O O . ASP C 1 156 ? 46.081 20.416 -31.547 1.00 28.85 ? 156 ASP C O 1 ATOM 3765 C CB . ASP C 1 156 ? 48.642 20.825 -32.438 1.00 35.04 ? 156 ASP C CB 1 ATOM 3766 C CG . ASP C 1 156 ? 50.140 20.847 -32.624 1.00 40.46 ? 156 ASP C CG 1 ATOM 3767 O OD1 . ASP C 1 156 ? 50.693 19.889 -33.229 1.00 40.75 ? 156 ASP C OD1 1 ATOM 3768 O OD2 . ASP C 1 156 ? 50.767 21.834 -32.160 1.00 42.85 ? 156 ASP C OD2 1 ATOM 3769 N N . VAL C 1 157 ? 46.088 18.181 -31.937 1.00 22.82 ? 157 VAL C N 1 ATOM 3770 C CA . VAL C 1 157 ? 44.753 17.966 -31.412 1.00 22.44 ? 157 VAL C CA 1 ATOM 3771 C C . VAL C 1 157 ? 44.692 16.652 -30.638 1.00 23.15 ? 157 VAL C C 1 ATOM 3772 O O . VAL C 1 157 ? 45.494 15.731 -30.872 1.00 20.98 ? 157 VAL C O 1 ATOM 3773 C CB . VAL C 1 157 ? 43.644 17.970 -32.528 1.00 21.76 ? 157 VAL C CB 1 ATOM 3774 C CG1 . VAL C 1 157 ? 43.802 19.162 -33.521 1.00 20.37 ? 157 VAL C CG1 1 ATOM 3775 C CG2 . VAL C 1 157 ? 43.607 16.652 -33.264 1.00 21.03 ? 157 VAL C CG2 1 ATOM 3776 N N . PHE C 1 158 ? 43.749 16.583 -29.702 1.00 22.10 ? 158 PHE C N 1 ATOM 3777 C CA . PHE C 1 158 ? 43.410 15.315 -29.048 1.00 23.88 ? 158 PHE C CA 1 ATOM 3778 C C . PHE C 1 158 ? 41.893 15.238 -28.876 1.00 25.01 ? 158 PHE C C 1 ATOM 3779 O O . PHE C 1 158 ? 41.207 16.269 -28.838 1.00 27.14 ? 158 PHE C O 1 ATOM 3780 C CB . PHE C 1 158 ? 44.156 15.132 -27.717 1.00 20.74 ? 158 PHE C CB 1 ATOM 3781 C CG . PHE C 1 158 ? 43.873 16.211 -26.705 1.00 20.96 ? 158 PHE C CG 1 ATOM 3782 C CD1 . PHE C 1 158 ? 42.769 16.129 -25.868 1.00 20.38 ? 158 PHE C CD1 1 ATOM 3783 C CD2 . PHE C 1 158 ? 44.710 17.318 -26.599 1.00 20.36 ? 158 PHE C CD2 1 ATOM 3784 C CE1 . PHE C 1 158 ? 42.493 17.147 -24.942 1.00 22.35 ? 158 PHE C CE1 1 ATOM 3785 C CE2 . PHE C 1 158 ? 44.440 18.335 -25.665 1.00 20.24 ? 158 PHE C CE2 1 ATOM 3786 C CZ . PHE C 1 158 ? 43.331 18.253 -24.847 1.00 19.26 ? 158 PHE C CZ 1 ATOM 3787 N N . SER C 1 159 ? 41.374 14.025 -28.766 1.00 24.86 ? 159 SER C N 1 ATOM 3788 C CA . SER C 1 159 ? 39.940 13.800 -28.856 1.00 25.70 ? 159 SER C CA 1 ATOM 3789 C C . SER C 1 159 ? 39.464 12.827 -27.796 1.00 24.81 ? 159 SER C C 1 ATOM 3790 O O . SER C 1 159 ? 40.179 11.886 -27.460 1.00 24.08 ? 159 SER C O 1 ATOM 3791 C CB . SER C 1 159 ? 39.596 13.229 -30.230 1.00 26.62 ? 159 SER C CB 1 ATOM 3792 O OG . SER C 1 159 ? 39.981 14.135 -31.241 1.00 35.28 ? 159 SER C OG 1 ATOM 3793 N N . PHE C 1 160 ? 38.235 13.024 -27.330 1.00 22.96 ? 160 PHE C N 1 ATOM 3794 C CA . PHE C 1 160 ? 37.657 12.184 -26.290 1.00 24.83 ? 160 PHE C CA 1 ATOM 3795 C C . PHE C 1 160 ? 36.401 11.434 -26.755 1.00 24.05 ? 160 PHE C C 1 ATOM 3796 O O . PHE C 1 160 ? 35.422 12.028 -27.211 1.00 24.91 ? 160 PHE C O 1 ATOM 3797 C CB . PHE C 1 160 ? 37.343 13.021 -25.042 1.00 24.93 ? 160 PHE C CB 1 ATOM 3798 C CG . PHE C 1 160 ? 38.509 13.177 -24.096 1.00 25.53 ? 160 PHE C CG 1 ATOM 3799 C CD1 . PHE C 1 160 ? 39.573 14.024 -24.403 1.00 25.93 ? 160 PHE C CD1 1 ATOM 3800 C CD2 . PHE C 1 160 ? 38.538 12.481 -22.890 1.00 25.54 ? 160 PHE C CD2 1 ATOM 3801 C CE1 . PHE C 1 160 ? 40.655 14.171 -23.518 1.00 25.83 ? 160 PHE C CE1 1 ATOM 3802 C CE2 . PHE C 1 160 ? 39.617 12.626 -21.998 1.00 24.19 ? 160 PHE C CE2 1 ATOM 3803 C CZ . PHE C 1 160 ? 40.668 13.476 -22.315 1.00 24.12 ? 160 PHE C CZ 1 ATOM 3804 N N . TYR C 1 161 ? 36.457 10.118 -26.665 1.00 23.06 ? 161 TYR C N 1 ATOM 3805 C CA . TYR C 1 161 ? 35.272 9.306 -26.802 1.00 24.67 ? 161 TYR C CA 1 ATOM 3806 C C . TYR C 1 161 ? 34.971 8.688 -25.440 1.00 25.36 ? 161 TYR C C 1 ATOM 3807 O O . TYR C 1 161 ? 35.772 7.907 -24.931 1.00 25.39 ? 161 TYR C O 1 ATOM 3808 C CB . TYR C 1 161 ? 35.461 8.209 -27.862 1.00 25.10 ? 161 TYR C CB 1 ATOM 3809 C CG . TYR C 1 161 ? 34.362 7.171 -27.834 1.00 25.93 ? 161 TYR C CG 1 ATOM 3810 C CD1 . TYR C 1 161 ? 33.041 7.527 -28.107 1.00 24.26 ? 161 TYR C CD1 1 ATOM 3811 C CD2 . TYR C 1 161 ? 34.635 5.839 -27.496 1.00 26.17 ? 161 TYR C CD2 1 ATOM 3812 C CE1 . TYR C 1 161 ? 32.026 6.593 -28.061 1.00 25.76 ? 161 TYR C CE1 1 ATOM 3813 C CE2 . TYR C 1 161 ? 33.617 4.887 -27.453 1.00 26.04 ? 161 TYR C CE2 1 ATOM 3814 C CZ . TYR C 1 161 ? 32.315 5.273 -27.742 1.00 26.15 ? 161 TYR C CZ 1 ATOM 3815 O OH . TYR C 1 161 ? 31.280 4.357 -27.704 1.00 26.86 ? 161 TYR C OH 1 ATOM 3816 N N . TYR C 1 162 ? 33.841 9.072 -24.851 1.00 24.61 ? 162 TYR C N 1 ATOM 3817 C CA . TYR C 1 162 ? 33.306 8.413 -23.657 1.00 25.42 ? 162 TYR C CA 1 ATOM 3818 C C . TYR C 1 162 ? 32.066 7.587 -24.047 1.00 26.44 ? 162 TYR C C 1 ATOM 3819 O O . TYR C 1 162 ? 31.163 8.097 -24.701 1.00 24.80 ? 162 TYR C O 1 ATOM 3820 C CB . TYR C 1 162 ? 32.900 9.447 -22.606 1.00 23.55 ? 162 TYR C CB 1 ATOM 3821 C CG . TYR C 1 162 ? 34.019 10.115 -21.844 1.00 24.34 ? 162 TYR C CG 1 ATOM 3822 C CD1 . TYR C 1 162 ? 35.337 9.633 -21.885 1.00 24.55 ? 162 TYR C CD1 1 ATOM 3823 C CD2 . TYR C 1 162 ? 33.749 11.210 -21.031 1.00 23.74 ? 162 TYR C CD2 1 ATOM 3824 C CE1 . TYR C 1 162 ? 36.358 10.265 -21.153 1.00 23.78 ? 162 TYR C CE1 1 ATOM 3825 C CE2 . TYR C 1 162 ? 34.753 11.833 -20.294 1.00 24.16 ? 162 TYR C CE2 1 ATOM 3826 C CZ . TYR C 1 162 ? 36.048 11.353 -20.354 1.00 23.74 ? 162 TYR C CZ 1 ATOM 3827 O OH . TYR C 1 162 ? 37.023 11.983 -19.611 1.00 24.21 ? 162 TYR C OH 1 ATOM 3828 N N . ASN C 1 163 ? 32.031 6.319 -23.660 1.00 28.74 ? 163 ASN C N 1 ATOM 3829 C CA . ASN C 1 163 ? 30.900 5.444 -23.970 1.00 31.52 ? 163 ASN C CA 1 ATOM 3830 C C . ASN C 1 163 ? 29.895 5.486 -22.825 1.00 33.87 ? 163 ASN C C 1 ATOM 3831 O O . ASN C 1 163 ? 30.179 6.050 -21.765 1.00 34.30 ? 163 ASN C O 1 ATOM 3832 C CB . ASN C 1 163 ? 31.398 4.009 -24.191 1.00 31.01 ? 163 ASN C CB 1 ATOM 3833 C CG . ASN C 1 163 ? 30.429 3.135 -25.025 1.00 31.94 ? 163 ASN C CG 1 ATOM 3834 O OD1 . ASN C 1 163 ? 29.319 3.539 -25.369 1.00 31.24 ? 163 ASN C OD1 1 ATOM 3835 N ND2 . ASN C 1 163 ? 30.874 1.918 -25.353 1.00 30.97 ? 163 ASN C ND2 1 ATOM 3836 N N . ARG C 1 164 ? 28.717 4.914 -23.056 1.00 37.48 ? 164 ARG C N 1 ATOM 3837 C CA . ARG C 1 164 ? 27.723 4.677 -22.009 1.00 41.60 ? 164 ARG C CA 1 ATOM 3838 C C . ARG C 1 164 ? 28.091 3.391 -21.261 1.00 40.91 ? 164 ARG C C 1 ATOM 3839 O O . ARG C 1 164 ? 28.594 2.445 -21.864 1.00 38.67 ? 164 ARG C O 1 ATOM 3840 C CB . ARG C 1 164 ? 26.316 4.586 -22.619 1.00 42.64 ? 164 ARG C CB 1 ATOM 3841 C CG . ARG C 1 164 ? 25.883 5.868 -23.320 1.00 44.96 ? 164 ARG C CG 1 ATOM 3842 C CD . ARG C 1 164 ? 24.544 5.743 -24.024 1.00 47.73 ? 164 ARG C CD 1 ATOM 3843 N NE . ARG C 1 164 ? 23.415 6.130 -23.170 1.00 53.50 ? 164 ARG C NE 1 ATOM 3844 C CZ . ARG C 1 164 ? 22.471 5.294 -22.738 1.00 55.97 ? 164 ARG C CZ 1 ATOM 3845 N NH1 . ARG C 1 164 ? 22.502 4.004 -23.073 1.00 56.92 ? 164 ARG C NH1 1 ATOM 3846 N NH2 . ARG C 1 164 ? 21.486 5.750 -21.974 1.00 56.85 ? 164 ARG C NH2 1 ATOM 3847 N N . ASP C 1 165 ? 27.845 3.377 -19.951 1.00 44.26 ? 165 ASP C N 1 ATOM 3848 C CA . ASP C 1 165 ? 28.272 2.287 -19.050 1.00 46.00 ? 165 ASP C CA 1 ATOM 3849 C C . ASP C 1 165 ? 27.969 0.882 -19.562 1.00 46.06 ? 165 ASP C C 1 ATOM 3850 O O . ASP C 1 165 ? 26.878 0.606 -20.049 1.00 46.24 ? 165 ASP C O 1 ATOM 3851 C CB . ASP C 1 165 ? 27.664 2.480 -17.660 1.00 48.74 ? 165 ASP C CB 1 ATOM 3852 C CG . ASP C 1 165 ? 28.394 1.692 -16.575 1.00 52.39 ? 165 ASP C CG 1 ATOM 3853 O OD1 . ASP C 1 165 ? 29.451 1.073 -16.860 1.00 53.90 ? 165 ASP C OD1 1 ATOM 3854 O OD2 . ASP C 1 165 ? 27.899 1.693 -15.423 1.00 53.28 ? 165 ASP C OD2 1 ATOM 3855 N N . SER D 2 1 ? 32.424 -4.298 -24.052 1.00 52.48 ? 171 SER D N 1 ATOM 3856 C CA . SER D 2 1 ? 32.321 -2.946 -24.602 1.00 51.79 ? 171 SER D CA 1 ATOM 3857 C C . SER D 2 1 ? 33.549 -2.079 -24.279 1.00 49.86 ? 171 SER D C 1 ATOM 3858 O O . SER D 2 1 ? 34.299 -2.359 -23.335 1.00 51.27 ? 171 SER D O 1 ATOM 3859 C CB . SER D 2 1 ? 31.048 -2.260 -24.102 1.00 52.91 ? 171 SER D CB 1 ATOM 3860 O OG . SER D 2 1 ? 30.922 -0.967 -24.667 1.00 55.10 ? 171 SER D OG 1 ATOM 3861 N N . LEU D 2 2 ? 33.741 -1.034 -25.079 1.00 44.80 ? 172 LEU D N 1 ATOM 3862 C CA . LEU D 2 2 ? 34.813 -0.070 -24.877 1.00 40.86 ? 172 LEU D CA 1 ATOM 3863 C C . LEU D 2 2 ? 34.332 1.045 -23.954 1.00 38.17 ? 172 LEU D C 1 ATOM 3864 O O . LEU D 2 2 ? 33.291 1.638 -24.203 1.00 36.87 ? 172 LEU D O 1 ATOM 3865 C CB . LEU D 2 2 ? 35.224 0.523 -26.229 1.00 41.61 ? 172 LEU D CB 1 ATOM 3866 C CG . LEU D 2 2 ? 36.501 1.349 -26.357 1.00 41.22 ? 172 LEU D CG 1 ATOM 3867 C CD1 . LEU D 2 2 ? 37.696 0.525 -25.986 1.00 40.82 ? 172 LEU D CD1 1 ATOM 3868 C CD2 . LEU D 2 2 ? 36.628 1.847 -27.782 1.00 40.98 ? 172 LEU D CD2 1 ATOM 3869 N N . GLY D 2 3 ? 35.098 1.340 -22.902 1.00 34.75 ? 173 GLY D N 1 ATOM 3870 C CA . GLY D 2 3 ? 34.691 2.337 -21.923 1.00 30.88 ? 173 GLY D CA 1 ATOM 3871 C C . GLY D 2 3 ? 34.775 3.759 -22.437 1.00 29.63 ? 173 GLY D C 1 ATOM 3872 O O . GLY D 2 3 ? 33.957 4.627 -22.087 1.00 27.08 ? 173 GLY D O 1 ATOM 3873 N N . GLY D 2 4 ? 35.779 3.986 -23.275 1.00 27.81 ? 174 GLY D N 1 ATOM 3874 C CA . GLY D 2 4 ? 36.135 5.309 -23.733 1.00 24.47 ? 174 GLY D CA 1 ATOM 3875 C C . GLY D 2 4 ? 37.459 5.210 -24.458 1.00 26.44 ? 174 GLY D C 1 ATOM 3876 O O . GLY D 2 4 ? 38.129 4.166 -24.414 1.00 26.49 ? 174 GLY D O 1 ATOM 3877 N N . GLN D 2 5 ? 37.834 6.293 -25.132 1.00 25.45 ? 175 GLN D N 1 ATOM 3878 C CA . GLN D 2 5 ? 39.065 6.337 -25.883 1.00 25.37 ? 175 GLN D CA 1 ATOM 3879 C C . GLN D 2 5 ? 39.539 7.772 -26.057 1.00 25.93 ? 175 GLN D C 1 ATOM 3880 O O . GLN D 2 5 ? 38.748 8.662 -26.363 1.00 26.47 ? 175 GLN D O 1 ATOM 3881 C CB . GLN D 2 5 ? 38.853 5.701 -27.250 1.00 26.88 ? 175 GLN D CB 1 ATOM 3882 C CG . GLN D 2 5 ? 40.118 5.563 -28.083 1.00 29.10 ? 175 GLN D CG 1 ATOM 3883 C CD . GLN D 2 5 ? 39.817 5.523 -29.560 1.00 32.25 ? 175 GLN D CD 1 ATOM 3884 O OE1 . GLN D 2 5 ? 39.054 6.351 -30.076 1.00 32.86 ? 175 GLN D OE1 1 ATOM 3885 N NE2 . GLN D 2 5 ? 40.408 4.562 -30.255 1.00 31.80 ? 175 GLN D NE2 1 ATOM 3886 N N . ILE D 2 6 ? 40.829 8.001 -25.857 1.00 24.87 ? 176 ILE D N 1 ATOM 3887 C CA . ILE D 2 6 ? 41.416 9.264 -26.299 1.00 25.88 ? 176 ILE D CA 1 ATOM 3888 C C . ILE D 2 6 ? 42.442 9.086 -27.424 1.00 26.07 ? 176 ILE D C 1 ATOM 3889 O O . ILE D 2 6 ? 43.283 8.181 -27.390 1.00 25.53 ? 176 ILE D O 1 ATOM 3890 C CB . ILE D 2 6 ? 41.923 10.201 -25.140 1.00 26.65 ? 176 ILE D CB 1 ATOM 3891 C CG1 . ILE D 2 6 ? 43.293 10.767 -25.462 1.00 26.45 ? 176 ILE D CG1 1 ATOM 3892 C CG2 . ILE D 2 6 ? 41.936 9.518 -23.783 1.00 28.25 ? 176 ILE D CG2 1 ATOM 3893 C CD1 . ILE D 2 6 ? 43.325 12.265 -25.362 1.00 27.65 ? 176 ILE D CD1 1 ATOM 3894 N N . VAL D 2 7 ? 42.326 9.939 -28.435 1.00 25.40 ? 177 VAL D N 1 ATOM 3895 C CA . VAL D 2 7 ? 43.237 9.910 -29.563 1.00 26.02 ? 177 VAL D CA 1 ATOM 3896 C C . VAL D 2 7 ? 44.135 11.145 -29.512 1.00 24.88 ? 177 VAL D C 1 ATOM 3897 O O . VAL D 2 7 ? 43.654 12.269 -29.454 1.00 24.76 ? 177 VAL D O 1 ATOM 3898 C CB . VAL D 2 7 ? 42.501 9.809 -30.934 1.00 25.99 ? 177 VAL D CB 1 ATOM 3899 C CG1 . VAL D 2 7 ? 43.504 9.904 -32.095 1.00 27.04 ? 177 VAL D CG1 1 ATOM 3900 C CG2 . VAL D 2 7 ? 41.697 8.507 -31.041 1.00 25.53 ? 177 VAL D CG2 1 ATOM 3901 N N . LEU D 2 8 ? 45.439 10.909 -29.527 1.00 23.91 ? 178 LEU D N 1 ATOM 3902 C CA . LEU D 2 8 ? 46.427 11.961 -29.637 1.00 24.98 ? 178 LEU D CA 1 ATOM 3903 C C . LEU D 2 8 ? 46.850 12.065 -31.093 1.00 26.24 ? 178 LEU D C 1 ATOM 3904 O O . LEU D 2 8 ? 47.266 11.069 -31.714 1.00 24.15 ? 178 LEU D O 1 ATOM 3905 C CB . LEU D 2 8 ? 47.642 11.635 -28.766 1.00 27.50 ? 178 LEU D CB 1 ATOM 3906 C CG . LEU D 2 8 ? 47.335 11.021 -27.397 1.00 27.79 ? 178 LEU D CG 1 ATOM 3907 C CD1 . LEU D 2 8 ? 48.526 10.259 -26.874 1.00 26.63 ? 178 LEU D CD1 1 ATOM 3908 C CD2 . LEU D 2 8 ? 46.894 12.123 -26.437 1.00 28.46 ? 178 LEU D CD2 1 ATOM 3909 N N . GLY D 2 9 ? 46.733 13.277 -31.624 1.00 25.72 ? 179 GLY D N 1 ATOM 3910 C CA . GLY D 2 9 ? 47.083 13.566 -32.992 1.00 28.25 ? 179 GLY D CA 1 ATOM 3911 C C . GLY D 2 9 ? 45.948 13.539 -34.002 1.00 28.25 ? 179 GLY D C 1 ATOM 3912 O O . GLY D 2 9 ? 46.201 13.689 -35.196 1.00 28.66 ? 179 GLY D O 1 ATOM 3913 N N . GLY D 2 10 ? 44.712 13.355 -33.535 1.00 27.69 ? 180 GLY D N 1 ATOM 3914 C CA . GLY D 2 10 ? 43.561 13.231 -34.426 1.00 27.71 ? 180 GLY D CA 1 ATOM 3915 C C . GLY D 2 10 ? 42.284 12.807 -33.721 1.00 29.77 ? 180 GLY D C 1 ATOM 3916 O O . GLY D 2 10 ? 42.113 13.060 -32.527 1.00 29.43 ? 180 GLY D O 1 ATOM 3917 N N . SER D 2 11 ? 41.394 12.152 -34.468 1.00 29.02 ? 181 SER D N 1 ATOM 3918 C CA . SER D 2 11 ? 40.124 11.678 -33.945 1.00 31.39 ? 181 SER D CA 1 ATOM 3919 C C . SER D 2 11 ? 39.786 10.328 -34.580 1.00 31.78 ? 181 SER D C 1 ATOM 3920 O O . SER D 2 11 ? 40.283 10.008 -35.656 1.00 32.28 ? 181 SER D O 1 ATOM 3921 C CB . SER D 2 11 ? 39.024 12.701 -34.233 1.00 32.12 ? 181 SER D CB 1 ATOM 3922 O OG . SER D 2 11 ? 38.789 12.782 -35.630 1.00 34.36 ? 181 SER D OG 1 ATOM 3923 N N . ASP D 2 12 ? 38.960 9.528 -33.913 1.00 31.88 ? 182 ASP D N 1 ATOM 3924 C CA . ASP D 2 12 ? 38.648 8.190 -34.419 1.00 32.68 ? 182 ASP D CA 1 ATOM 3925 C C . ASP D 2 12 ? 37.246 8.132 -35.051 1.00 32.27 ? 182 ASP D C 1 ATOM 3926 O O . ASP D 2 12 ? 36.242 8.107 -34.329 1.00 29.98 ? 182 ASP D O 1 ATOM 3927 C CB . ASP D 2 12 ? 38.817 7.146 -33.317 1.00 33.61 ? 182 ASP D CB 1 ATOM 3928 C CG . ASP D 2 12 ? 38.712 5.711 -33.832 1.00 35.68 ? 182 ASP D CG 1 ATOM 3929 O OD1 . ASP D 2 12 ? 38.506 5.508 -35.049 1.00 35.39 ? 182 ASP D OD1 1 ATOM 3930 O OD2 . ASP D 2 12 ? 38.828 4.774 -33.003 1.00 36.20 ? 182 ASP D OD2 1 ATOM 3931 N N . PRO D 2 13 ? 37.184 8.111 -36.404 1.00 31.68 ? 183 PRO D N 1 ATOM 3932 C CA . PRO D 2 13 ? 35.946 8.132 -37.191 1.00 32.74 ? 183 PRO D CA 1 ATOM 3933 C C . PRO D 2 13 ? 34.956 7.041 -36.831 1.00 33.22 ? 183 PRO D C 1 ATOM 3934 O O . PRO D 2 13 ? 33.750 7.256 -36.945 1.00 32.62 ? 183 PRO D O 1 ATOM 3935 C CB . PRO D 2 13 ? 36.436 7.939 -38.618 1.00 32.50 ? 183 PRO D CB 1 ATOM 3936 C CG . PRO D 2 13 ? 37.794 8.485 -38.604 1.00 31.90 ? 183 PRO D CG 1 ATOM 3937 C CD . PRO D 2 13 ? 38.361 8.083 -37.285 1.00 31.50 ? 183 PRO D CD 1 ATOM 3938 N N . GLN D 2 14 ? 35.459 5.900 -36.370 1.00 35.21 ? 184 GLN D N 1 ATOM 3939 C CA . GLN D 2 14 ? 34.595 4.808 -35.929 1.00 39.50 ? 184 GLN D CA 1 ATOM 3940 C C . GLN D 2 14 ? 33.793 5.118 -34.645 1.00 36.55 ? 184 GLN D C 1 ATOM 3941 O O . GLN D 2 14 ? 32.909 4.350 -34.279 1.00 35.10 ? 184 GLN D O 1 ATOM 3942 C CB . GLN D 2 14 ? 35.387 3.487 -35.801 1.00 41.44 ? 184 GLN D CB 1 ATOM 3943 C CG . GLN D 2 14 ? 36.064 3.271 -34.458 1.00 45.01 ? 184 GLN D CG 1 ATOM 3944 C CD . GLN D 2 14 ? 36.854 1.959 -34.375 1.00 46.75 ? 184 GLN D CD 1 ATOM 3945 O OE1 . GLN D 2 14 ? 38.079 1.967 -34.162 1.00 49.45 ? 184 GLN D OE1 1 ATOM 3946 N NE2 . GLN D 2 14 ? 36.158 0.827 -34.533 1.00 48.30 ? 184 GLN D NE2 1 ATOM 3947 N N . HIS D 2 15 ? 34.078 6.250 -33.996 1.00 36.03 ? 185 HIS D N 1 ATOM 3948 C CA . HIS D 2 15 ? 33.414 6.620 -32.735 1.00 36.04 ? 185 HIS D CA 1 ATOM 3949 C C . HIS D 2 15 ? 32.591 7.902 -32.753 1.00 37.37 ? 185 HIS D C 1 ATOM 3950 O O . HIS D 2 15 ? 31.999 8.284 -31.742 1.00 37.80 ? 185 HIS D O 1 ATOM 3951 C CB . HIS D 2 15 ? 34.420 6.664 -31.593 1.00 36.29 ? 185 HIS D CB 1 ATOM 3952 C CG . HIS D 2 15 ? 34.956 5.319 -31.223 1.00 36.69 ? 185 HIS D CG 1 ATOM 3953 N ND1 . HIS D 2 15 ? 36.304 5.048 -31.155 1.00 37.17 ? 185 HIS D ND1 1 ATOM 3954 C CD2 . HIS D 2 15 ? 34.322 4.164 -30.913 1.00 36.96 ? 185 HIS D CD2 1 ATOM 3955 C CE1 . HIS D 2 15 ? 36.479 3.785 -30.812 1.00 37.90 ? 185 HIS D CE1 1 ATOM 3956 N NE2 . HIS D 2 15 ? 35.291 3.227 -30.659 1.00 38.39 ? 185 HIS D NE2 1 ATOM 3957 N N . TYR D 2 16 ? 32.547 8.571 -33.897 1.00 38.41 ? 186 TYR D N 1 ATOM 3958 C CA . TYR D 2 16 ? 31.572 9.633 -34.099 1.00 38.80 ? 186 TYR D CA 1 ATOM 3959 C C . TYR D 2 16 ? 30.872 9.497 -35.453 1.00 38.88 ? 186 TYR D C 1 ATOM 3960 O O . TYR D 2 16 ? 31.276 8.704 -36.304 1.00 38.45 ? 186 TYR D O 1 ATOM 3961 C CB . TYR D 2 16 ? 32.219 11.015 -33.952 1.00 38.57 ? 186 TYR D CB 1 ATOM 3962 C CG . TYR D 2 16 ? 33.238 11.361 -35.014 1.00 38.35 ? 186 TYR D CG 1 ATOM 3963 C CD1 . TYR D 2 16 ? 34.583 11.078 -34.821 1.00 38.00 ? 186 TYR D CD1 1 ATOM 3964 C CD2 . TYR D 2 16 ? 32.860 11.991 -36.205 1.00 38.20 ? 186 TYR D CD2 1 ATOM 3965 C CE1 . TYR D 2 16 ? 35.525 11.391 -35.777 1.00 38.61 ? 186 TYR D CE1 1 ATOM 3966 C CE2 . TYR D 2 16 ? 33.803 12.316 -37.178 1.00 38.27 ? 186 TYR D CE2 1 ATOM 3967 C CZ . TYR D 2 16 ? 35.138 12.008 -36.952 1.00 39.11 ? 186 TYR D CZ 1 ATOM 3968 O OH . TYR D 2 16 ? 36.101 12.314 -37.889 1.00 39.77 ? 186 TYR D OH 1 ATOM 3969 N N . GLU D 2 17 ? 29.820 10.276 -35.646 1.00 39.33 ? 187 GLU D N 1 ATOM 3970 C CA . GLU D 2 17 ? 29.203 10.365 -36.963 1.00 39.80 ? 187 GLU D CA 1 ATOM 3971 C C . GLU D 2 17 ? 28.930 11.796 -37.382 1.00 37.79 ? 187 GLU D C 1 ATOM 3972 O O . GLU D 2 17 ? 28.851 12.713 -36.554 1.00 35.94 ? 187 GLU D O 1 ATOM 3973 C CB . GLU D 2 17 ? 27.930 9.531 -37.052 1.00 42.58 ? 187 GLU D CB 1 ATOM 3974 C CG . GLU D 2 17 ? 26.859 9.911 -36.075 1.00 46.03 ? 187 GLU D CG 1 ATOM 3975 C CD . GLU D 2 17 ? 25.805 8.843 -35.985 1.00 49.66 ? 187 GLU D CD 1 ATOM 3976 O OE1 . GLU D 2 17 ? 26.144 7.724 -35.528 1.00 49.55 ? 187 GLU D OE1 1 ATOM 3977 O OE2 . GLU D 2 17 ? 24.639 9.124 -36.376 1.00 51.76 ? 187 GLU D OE2 1 ATOM 3978 N N . GLY D 2 18 ? 28.771 11.958 -38.684 1.00 35.69 ? 188 GLY D N 1 ATOM 3979 C CA . GLY D 2 18 ? 28.658 13.261 -39.277 1.00 33.23 ? 188 GLY D CA 1 ATOM 3980 C C . GLY D 2 18 ? 30.007 13.923 -39.253 1.00 31.58 ? 188 GLY D C 1 ATOM 3981 O O . GLY D 2 18 ? 31.042 13.272 -39.376 1.00 31.60 ? 188 GLY D O 1 ATOM 3982 N N . ASN D 2 19 ? 29.982 15.229 -39.048 1.00 31.79 ? 189 ASN D N 1 ATOM 3983 C CA . ASN D 2 19 ? 31.165 16.045 -39.151 1.00 31.99 ? 189 ASN D CA 1 ATOM 3984 C C . ASN D 2 19 ? 31.275 16.869 -37.888 1.00 31.75 ? 189 ASN D C 1 ATOM 3985 O O . ASN D 2 19 ? 30.286 17.058 -37.182 1.00 32.51 ? 189 ASN D O 1 ATOM 3986 C CB . ASN D 2 19 ? 31.054 16.967 -40.379 1.00 31.42 ? 189 ASN D CB 1 ATOM 3987 C CG . ASN D 2 19 ? 30.588 16.228 -41.626 1.00 33.33 ? 189 ASN D CG 1 ATOM 3988 O OD1 . ASN D 2 19 ? 31.332 15.432 -42.223 1.00 31.26 ? 189 ASN D OD1 1 ATOM 3989 N ND2 . ASN D 2 19 ? 29.338 16.479 -42.018 1.00 33.27 ? 189 ASN D ND2 1 ATOM 3990 N N . PHE D 2 20 ? 32.478 17.357 -37.609 1.00 30.78 ? 190 PHE D N 1 ATOM 3991 C CA . PHE D 2 20 ? 32.697 18.254 -36.492 1.00 30.32 ? 190 PHE D CA 1 ATOM 3992 C C . PHE D 2 20 ? 32.238 19.650 -36.821 1.00 31.36 ? 190 PHE D C 1 ATOM 3993 O O . PHE D 2 20 ? 32.448 20.149 -37.937 1.00 32.55 ? 190 PHE D O 1 ATOM 3994 C CB . PHE D 2 20 ? 34.170 18.294 -36.119 1.00 28.93 ? 190 PHE D CB 1 ATOM 3995 C CG . PHE D 2 20 ? 34.634 17.077 -35.396 1.00 29.88 ? 190 PHE D CG 1 ATOM 3996 C CD1 . PHE D 2 20 ? 34.343 16.898 -34.049 1.00 27.88 ? 190 PHE D CD1 1 ATOM 3997 C CD2 . PHE D 2 20 ? 35.360 16.103 -36.056 1.00 30.25 ? 190 PHE D CD2 1 ATOM 3998 C CE1 . PHE D 2 20 ? 34.771 15.762 -33.380 1.00 28.33 ? 190 PHE D CE1 1 ATOM 3999 C CE2 . PHE D 2 20 ? 35.809 14.970 -35.379 1.00 30.68 ? 190 PHE D CE2 1 ATOM 4000 C CZ . PHE D 2 20 ? 35.514 14.808 -34.043 1.00 29.40 ? 190 PHE D CZ 1 ATOM 4001 N N . HIS D 2 21 ? 31.602 20.276 -35.843 1.00 30.06 ? 191 HIS D N 1 ATOM 4002 C CA . HIS D 2 21 ? 31.382 21.696 -35.896 1.00 32.20 ? 191 HIS D CA 1 ATOM 4003 C C . HIS D 2 21 ? 32.131 22.262 -34.705 1.00 30.71 ? 191 HIS D C 1 ATOM 4004 O O . HIS D 2 21 ? 32.148 21.660 -33.630 1.00 30.91 ? 191 HIS D O 1 ATOM 4005 C CB . HIS D 2 21 ? 29.885 22.022 -35.930 1.00 36.02 ? 191 HIS D CB 1 ATOM 4006 C CG . HIS D 2 21 ? 29.158 21.338 -37.054 1.00 40.29 ? 191 HIS D CG 1 ATOM 4007 N ND1 . HIS D 2 21 ? 28.393 20.204 -36.869 1.00 42.18 ? 191 HIS D ND1 1 ATOM 4008 C CD2 . HIS D 2 21 ? 29.130 21.592 -38.385 1.00 40.93 ? 191 HIS D CD2 1 ATOM 4009 C CE1 . HIS D 2 21 ? 27.897 19.811 -38.029 1.00 41.39 ? 191 HIS D CE1 1 ATOM 4010 N NE2 . HIS D 2 21 ? 28.329 20.636 -38.966 1.00 41.75 ? 191 HIS D NE2 1 ATOM 4011 N N . TYR D 2 22 ? 32.801 23.388 -34.928 1.00 28.37 ? 192 TYR D N 1 ATOM 4012 C CA . TYR D 2 22 ? 33.801 23.898 -34.010 1.00 27.11 ? 192 TYR D CA 1 ATOM 4013 C C . TYR D 2 22 ? 33.360 25.191 -33.366 1.00 28.73 ? 192 TYR D C 1 ATOM 4014 O O . TYR D 2 22 ? 32.568 25.932 -33.938 1.00 31.26 ? 192 TYR D O 1 ATOM 4015 C CB . TYR D 2 22 ? 35.127 24.113 -34.747 1.00 26.12 ? 192 TYR D CB 1 ATOM 4016 C CG . TYR D 2 22 ? 35.780 22.836 -35.220 1.00 26.23 ? 192 TYR D CG 1 ATOM 4017 C CD1 . TYR D 2 22 ? 36.670 22.150 -34.399 1.00 25.82 ? 192 TYR D CD1 1 ATOM 4018 C CD2 . TYR D 2 22 ? 35.496 22.300 -36.480 1.00 26.54 ? 192 TYR D CD2 1 ATOM 4019 C CE1 . TYR D 2 22 ? 37.261 20.982 -34.804 1.00 24.98 ? 192 TYR D CE1 1 ATOM 4020 C CE2 . TYR D 2 22 ? 36.090 21.127 -36.899 1.00 25.79 ? 192 TYR D CE2 1 ATOM 4021 C CZ . TYR D 2 22 ? 36.976 20.468 -36.047 1.00 25.93 ? 192 TYR D CZ 1 ATOM 4022 O OH . TYR D 2 22 ? 37.592 19.295 -36.443 1.00 26.06 ? 192 TYR D OH 1 ATOM 4023 N N . ILE D 2 23 ? 33.888 25.458 -32.173 1.00 29.86 ? 193 ILE D N 1 ATOM 4024 C CA . ILE D 2 23 ? 33.626 26.697 -31.444 1.00 29.36 ? 193 ILE D CA 1 ATOM 4025 C C . ILE D 2 23 ? 34.977 27.185 -30.942 1.00 29.79 ? 193 ILE D C 1 ATOM 4026 O O . ILE D 2 23 ? 35.703 26.429 -30.310 1.00 30.81 ? 193 ILE D O 1 ATOM 4027 C CB . ILE D 2 23 ? 32.621 26.484 -30.258 1.00 29.43 ? 193 ILE D CB 1 ATOM 4028 C CG1 . ILE D 2 23 ? 31.370 25.715 -30.714 1.00 27.72 ? 193 ILE D CG1 1 ATOM 4029 C CG2 . ILE D 2 23 ? 32.201 27.829 -29.615 1.00 28.43 ? 193 ILE D CG2 1 ATOM 4030 C CD1 . ILE D 2 23 ? 31.357 24.253 -30.316 1.00 26.75 ? 193 ILE D CD1 1 ATOM 4031 N N . ASN D 2 24 ? 35.333 28.428 -31.259 1.00 30.84 ? 194 ASN D N 1 ATOM 4032 C CA . ASN D 2 24 ? 36.615 28.987 -30.819 1.00 31.83 ? 194 ASN D CA 1 ATOM 4033 C C . ASN D 2 24 ? 36.614 29.275 -29.340 1.00 30.35 ? 194 ASN D C 1 ATOM 4034 O O . ASN D 2 24 ? 35.577 29.626 -28.769 1.00 29.90 ? 194 ASN D O 1 ATOM 4035 C CB . ASN D 2 24 ? 36.933 30.303 -31.520 1.00 34.95 ? 194 ASN D CB 1 ATOM 4036 C CG . ASN D 2 24 ? 36.945 30.191 -33.013 1.00 35.93 ? 194 ASN D CG 1 ATOM 4037 O OD1 . ASN D 2 24 ? 36.798 31.197 -33.698 1.00 38.37 ? 194 ASN D OD1 1 ATOM 4038 N ND2 . ASN D 2 24 ? 37.119 28.982 -33.535 1.00 36.19 ? 194 ASN D ND2 1 ATOM 4039 N N . LEU D 2 25 ? 37.783 29.141 -28.727 1.00 30.05 ? 195 LEU D N 1 ATOM 4040 C CA . LEU D 2 25 ? 37.953 29.488 -27.325 1.00 29.42 ? 195 LEU D CA 1 ATOM 4041 C C . LEU D 2 25 ? 37.804 30.991 -27.136 1.00 32.60 ? 195 LEU D C 1 ATOM 4042 O O . LEU D 2 25 ? 38.171 31.783 -28.023 1.00 31.07 ? 195 LEU D O 1 ATOM 4043 C CB . LEU D 2 25 ? 39.311 29.042 -26.817 1.00 27.02 ? 195 LEU D CB 1 ATOM 4044 C CG . LEU D 2 25 ? 39.690 27.565 -26.882 1.00 25.61 ? 195 LEU D CG 1 ATOM 4045 C CD1 . LEU D 2 25 ? 41.023 27.343 -26.170 1.00 24.58 ? 195 LEU D CD1 1 ATOM 4046 C CD2 . LEU D 2 25 ? 38.602 26.720 -26.267 1.00 26.65 ? 195 LEU D CD2 1 ATOM 4047 N N . ILE D 2 26 ? 37.245 31.372 -25.986 1.00 35.32 ? 196 ILE D N 1 ATOM 4048 C CA . ILE D 2 26 ? 37.099 32.776 -25.613 1.00 38.93 ? 196 ILE D CA 1 ATOM 4049 C C . ILE D 2 26 ? 38.478 33.419 -25.579 1.00 41.60 ? 196 ILE D C 1 ATOM 4050 O O . ILE D 2 26 ? 38.702 34.470 -26.191 1.00 41.61 ? 196 ILE D O 1 ATOM 4051 C CB . ILE D 2 26 ? 36.361 32.921 -24.270 1.00 39.83 ? 196 ILE D CB 1 ATOM 4052 C CG1 . ILE D 2 26 ? 34.863 32.704 -24.481 1.00 40.70 ? 196 ILE D CG1 1 ATOM 4053 C CG2 . ILE D 2 26 ? 36.605 34.291 -23.642 1.00 40.83 ? 196 ILE D CG2 1 ATOM 4054 C CD1 . ILE D 2 26 ? 34.158 32.181 -23.249 1.00 43.12 ? 196 ILE D CD1 1 ATOM 4055 N N . LYS D 2 27 ? 39.393 32.756 -24.877 1.00 44.39 ? 197 LYS D N 1 ATOM 4056 C CA . LYS D 2 27 ? 40.812 33.093 -24.874 1.00 46.96 ? 197 LYS D CA 1 ATOM 4057 C C . LYS D 2 27 ? 41.606 31.817 -24.637 1.00 48.77 ? 197 LYS D C 1 ATOM 4058 O O . LYS D 2 27 ? 41.168 30.917 -23.898 1.00 49.93 ? 197 LYS D O 1 ATOM 4059 C CB . LYS D 2 27 ? 41.142 34.110 -23.781 1.00 48.29 ? 197 LYS D CB 1 ATOM 4060 C CG . LYS D 2 27 ? 40.612 33.728 -22.401 1.00 49.91 ? 197 LYS D CG 1 ATOM 4061 C CD . LYS D 2 27 ? 41.469 34.279 -21.270 1.00 51.03 ? 197 LYS D CD 1 ATOM 4062 C CE . LYS D 2 27 ? 40.686 34.308 -19.956 1.00 53.20 ? 197 LYS D CE 1 ATOM 4063 N NZ . LYS D 2 27 ? 39.802 33.100 -19.769 1.00 53.54 ? 197 LYS D NZ 1 ATOM 4064 N N . THR D 2 28 ? 42.772 31.734 -25.265 1.00 48.51 ? 198 THR D N 1 ATOM 4065 C CA . THR D 2 28 ? 43.686 30.628 -25.024 1.00 47.91 ? 198 THR D CA 1 ATOM 4066 C C . THR D 2 28 ? 43.983 30.523 -23.512 1.00 45.81 ? 198 THR D C 1 ATOM 4067 O O . THR D 2 28 ? 43.760 31.479 -22.756 1.00 46.27 ? 198 THR D O 1 ATOM 4068 C CB . THR D 2 28 ? 44.981 30.779 -25.872 1.00 49.18 ? 198 THR D CB 1 ATOM 4069 O OG1 . THR D 2 28 ? 45.756 29.575 -25.803 1.00 51.06 ? 198 THR D OG1 1 ATOM 4070 C CG2 . THR D 2 28 ? 45.826 31.964 -25.399 1.00 49.85 ? 198 THR D CG2 1 ATOM 4071 N N . GLY D 2 29 ? 44.452 29.362 -23.071 1.00 42.40 ? 199 GLY D N 1 ATOM 4072 C CA . GLY D 2 29 ? 44.797 29.172 -21.668 1.00 41.73 ? 199 GLY D CA 1 ATOM 4073 C C . GLY D 2 29 ? 43.798 28.332 -20.893 1.00 39.86 ? 199 GLY D C 1 ATOM 4074 O O . GLY D 2 29 ? 44.131 27.759 -19.851 1.00 39.05 ? 199 GLY D O 1 ATOM 4075 N N . VAL D 2 30 ? 42.578 28.247 -21.418 1.00 37.88 ? 200 VAL D N 1 ATOM 4076 C CA . VAL D 2 30 ? 41.500 27.505 -20.780 1.00 37.33 ? 200 VAL D CA 1 ATOM 4077 C C . VAL D 2 30 ? 40.560 26.911 -21.845 1.00 36.71 ? 200 VAL D C 1 ATOM 4078 O O . VAL D 2 30 ? 40.213 27.584 -22.818 1.00 37.10 ? 200 VAL D O 1 ATOM 4079 C CB . VAL D 2 30 ? 40.745 28.402 -19.744 1.00 36.94 ? 200 VAL D CB 1 ATOM 4080 C CG1 . VAL D 2 30 ? 40.180 29.650 -20.398 1.00 38.01 ? 200 VAL D CG1 1 ATOM 4081 C CG2 . VAL D 2 30 ? 39.644 27.635 -19.035 1.00 38.27 ? 200 VAL D CG2 1 ATOM 4082 N N . TRP D 2 31 ? 40.157 25.653 -21.660 1.00 34.83 ? 201 TRP D N 1 ATOM 4083 C CA . TRP D 2 31 ? 39.247 24.985 -22.601 1.00 31.69 ? 201 TRP D CA 1 ATOM 4084 C C . TRP D 2 31 ? 37.807 25.426 -22.363 1.00 32.26 ? 201 TRP D C 1 ATOM 4085 O O . TRP D 2 31 ? 36.951 24.632 -21.942 1.00 31.05 ? 201 TRP D O 1 ATOM 4086 C CB . TRP D 2 31 ? 39.365 23.465 -22.508 1.00 28.15 ? 201 TRP D CB 1 ATOM 4087 C CG . TRP D 2 31 ? 40.640 22.911 -23.059 1.00 27.75 ? 201 TRP D CG 1 ATOM 4088 C CD1 . TRP D 2 31 ? 41.625 22.295 -22.354 1.00 27.96 ? 201 TRP D CD1 1 ATOM 4089 C CD2 . TRP D 2 31 ? 41.069 22.919 -24.430 1.00 28.09 ? 201 TRP D CD2 1 ATOM 4090 N NE1 . TRP D 2 31 ? 42.642 21.911 -23.193 1.00 28.79 ? 201 TRP D NE1 1 ATOM 4091 C CE2 . TRP D 2 31 ? 42.330 22.288 -24.474 1.00 27.67 ? 201 TRP D CE2 1 ATOM 4092 C CE3 . TRP D 2 31 ? 40.515 23.412 -25.625 1.00 28.30 ? 201 TRP D CE3 1 ATOM 4093 C CZ2 . TRP D 2 31 ? 43.050 22.117 -25.666 1.00 27.10 ? 201 TRP D CZ2 1 ATOM 4094 C CZ3 . TRP D 2 31 ? 41.243 23.252 -26.819 1.00 28.35 ? 201 TRP D CZ3 1 ATOM 4095 C CH2 . TRP D 2 31 ? 42.498 22.608 -26.822 1.00 27.61 ? 201 TRP D CH2 1 ATOM 4096 N N . GLN D 2 32 ? 37.550 26.700 -22.653 1.00 31.80 ? 202 GLN D N 1 ATOM 4097 C CA . GLN D 2 32 ? 36.292 27.336 -22.299 1.00 32.18 ? 202 GLN D CA 1 ATOM 4098 C C . GLN D 2 32 ? 35.756 28.143 -23.471 1.00 31.70 ? 202 GLN D C 1 ATOM 4099 O O . GLN D 2 32 ? 36.480 28.922 -24.093 1.00 30.50 ? 202 GLN D O 1 ATOM 4100 C CB . GLN D 2 32 ? 36.511 28.230 -21.078 1.00 31.83 ? 202 GLN D CB 1 ATOM 4101 C CG . GLN D 2 32 ? 35.269 28.886 -20.496 1.00 33.81 ? 202 GLN D CG 1 ATOM 4102 C CD . GLN D 2 32 ? 35.580 29.610 -19.203 1.00 34.87 ? 202 GLN D CD 1 ATOM 4103 O OE1 . GLN D 2 32 ? 36.561 30.349 -19.113 1.00 36.86 ? 202 GLN D OE1 1 ATOM 4104 N NE2 . GLN D 2 32 ? 34.760 29.387 -18.187 1.00 36.03 ? 202 GLN D NE2 1 ATOM 4105 N N . ILE D 2 33 ? 34.474 27.960 -23.748 1.00 33.58 ? 203 ILE D N 1 ATOM 4106 C CA . ILE D 2 33 ? 33.836 28.555 -24.909 1.00 37.21 ? 203 ILE D CA 1 ATOM 4107 C C . ILE D 2 33 ? 32.604 29.347 -24.492 1.00 41.31 ? 203 ILE D C 1 ATOM 4108 O O . ILE D 2 33 ? 32.077 29.158 -23.395 1.00 42.36 ? 203 ILE D O 1 ATOM 4109 C CB . ILE D 2 33 ? 33.428 27.470 -25.938 1.00 36.53 ? 203 ILE D CB 1 ATOM 4110 C CG1 . ILE D 2 33 ? 32.482 26.434 -25.287 1.00 35.97 ? 203 ILE D CG1 1 ATOM 4111 C CG2 . ILE D 2 33 ? 34.678 26.826 -26.556 1.00 36.33 ? 203 ILE D CG2 1 ATOM 4112 C CD1 . ILE D 2 33 ? 31.991 25.326 -26.222 1.00 36.28 ? 203 ILE D CD1 1 ATOM 4113 N N . GLN D 2 34 ? 32.157 30.235 -25.376 1.00 44.80 ? 204 GLN D N 1 ATOM 4114 C CA . GLN D 2 34 ? 30.917 30.975 -25.192 1.00 47.67 ? 204 GLN D CA 1 ATOM 4115 C C . GLN D 2 34 ? 29.720 30.059 -25.399 1.00 48.07 ? 204 GLN D C 1 ATOM 4116 O O . GLN D 2 34 ? 29.707 29.235 -26.323 1.00 47.24 ? 204 GLN D O 1 ATOM 4117 C CB . GLN D 2 34 ? 30.841 32.131 -26.190 1.00 51.07 ? 204 GLN D CB 1 ATOM 4118 C CG . GLN D 2 34 ? 29.829 33.209 -25.833 1.00 55.31 ? 204 GLN D CG 1 ATOM 4119 C CD . GLN D 2 34 ? 30.411 34.252 -24.901 1.00 58.18 ? 204 GLN D CD 1 ATOM 4120 O OE1 . GLN D 2 34 ? 31.310 35.011 -25.285 1.00 59.78 ? 204 GLN D OE1 1 ATOM 4121 N NE2 . GLN D 2 34 ? 29.903 34.299 -23.664 1.00 58.88 ? 204 GLN D NE2 1 ATOM 4122 N N . MET D 2 35 ? 28.725 30.207 -24.528 1.00 48.49 ? 205 MET D N 1 ATOM 4123 C CA . MET D 2 35 ? 27.435 29.532 -24.672 1.00 49.28 ? 205 MET D CA 1 ATOM 4124 C C . MET D 2 35 ? 26.337 30.583 -24.900 1.00 50.03 ? 205 MET D C 1 ATOM 4125 O O . MET D 2 35 ? 26.341 31.644 -24.276 1.00 49.51 ? 205 MET D O 1 ATOM 4126 C CB . MET D 2 35 ? 27.146 28.662 -23.443 1.00 48.52 ? 205 MET D CB 1 ATOM 4127 C CG . MET D 2 35 ? 25.795 27.946 -23.439 1.00 48.19 ? 205 MET D CG 1 ATOM 4128 S SD . MET D 2 35 ? 25.813 26.319 -22.642 1.00 49.27 ? 205 MET D SD 1 ATOM 4129 C CE . MET D 2 35 ? 26.577 26.687 -21.079 1.00 48.59 ? 205 MET D CE 1 ATOM 4130 N N . LYS D 2 36 ? 25.406 30.287 -25.798 1.00 50.47 ? 206 LYS D N 1 ATOM 4131 C CA . LYS D 2 36 ? 24.421 31.278 -26.217 1.00 52.89 ? 206 LYS D CA 1 ATOM 4132 C C . LYS D 2 36 ? 22.998 30.987 -25.744 1.00 53.98 ? 206 LYS D C 1 ATOM 4133 O O . LYS D 2 36 ? 22.071 31.696 -26.133 1.00 55.58 ? 206 LYS D O 1 ATOM 4134 C CB . LYS D 2 36 ? 24.426 31.410 -27.742 1.00 53.92 ? 206 LYS D CB 1 ATOM 4135 C CG . LYS D 2 36 ? 25.779 31.711 -28.359 1.00 55.20 ? 206 LYS D CG 1 ATOM 4136 C CD . LYS D 2 36 ? 25.801 31.277 -29.818 1.00 56.04 ? 206 LYS D CD 1 ATOM 4137 C CE . LYS D 2 36 ? 26.658 32.207 -30.653 1.00 55.12 ? 206 LYS D CE 1 ATOM 4138 N NZ . LYS D 2 36 ? 26.505 31.885 -32.090 1.00 55.59 ? 206 LYS D NZ 1 ATOM 4139 N N . GLY D 2 37 ? 22.816 29.953 -24.923 1.00 53.95 ? 207 GLY D N 1 ATOM 4140 C CA . GLY D 2 37 ? 21.487 29.625 -24.408 1.00 53.86 ? 207 GLY D CA 1 ATOM 4141 C C . GLY D 2 37 ? 21.240 28.161 -24.105 1.00 54.36 ? 207 GLY D C 1 ATOM 4142 O O . GLY D 2 37 ? 21.655 27.280 -24.861 1.00 54.51 ? 207 GLY D O 1 ATOM 4143 N N . VAL D 2 38 ? 20.564 27.909 -22.985 1.00 54.69 ? 208 VAL D N 1 ATOM 4144 C CA . VAL D 2 38 ? 20.098 26.566 -22.633 1.00 54.98 ? 208 VAL D CA 1 ATOM 4145 C C . VAL D 2 38 ? 18.579 26.510 -22.753 1.00 56.88 ? 208 VAL D C 1 ATOM 4146 O O . VAL D 2 38 ? 17.862 27.245 -22.066 1.00 57.83 ? 208 VAL D O 1 ATOM 4147 C CB . VAL D 2 38 ? 20.523 26.142 -21.209 1.00 53.88 ? 208 VAL D CB 1 ATOM 4148 C CG1 . VAL D 2 38 ? 20.009 24.743 -20.899 1.00 53.10 ? 208 VAL D CG1 1 ATOM 4149 C CG2 . VAL D 2 38 ? 22.032 26.194 -21.058 1.00 53.01 ? 208 VAL D CG2 1 ATOM 4150 N N . SER D 2 39 ? 18.103 25.640 -23.637 1.00 57.97 ? 209 SER D N 1 ATOM 4151 C CA . SER D 2 39 ? 16.684 25.461 -23.878 1.00 59.31 ? 209 SER D CA 1 ATOM 4152 C C . SER D 2 39 ? 16.188 24.189 -23.216 1.00 60.79 ? 209 SER D C 1 ATOM 4153 O O . SER D 2 39 ? 16.834 23.143 -23.304 1.00 60.90 ? 209 SER D O 1 ATOM 4154 C CB . SER D 2 39 ? 16.399 25.378 -25.383 1.00 60.11 ? 209 SER D CB 1 ATOM 4155 O OG . SER D 2 39 ? 16.990 26.453 -26.091 1.00 60.88 ? 209 SER D OG 1 ATOM 4156 N N . VAL D 2 40 ? 15.042 24.296 -22.547 1.00 62.38 ? 210 VAL D N 1 ATOM 4157 C CA . VAL D 2 40 ? 14.247 23.135 -22.150 1.00 62.93 ? 210 VAL D CA 1 ATOM 4158 C C . VAL D 2 40 ? 13.076 23.058 -23.124 1.00 63.58 ? 210 VAL D C 1 ATOM 4159 O O . VAL D 2 40 ? 12.406 24.065 -23.374 1.00 64.29 ? 210 VAL D O 1 ATOM 4160 C CB . VAL D 2 40 ? 13.739 23.244 -20.694 1.00 62.57 ? 210 VAL D CB 1 ATOM 4161 C CG1 . VAL D 2 40 ? 12.730 22.150 -20.395 1.00 63.04 ? 210 VAL D CG1 1 ATOM 4162 C CG2 . VAL D 2 40 ? 14.896 23.160 -19.717 1.00 62.06 ? 210 VAL D CG2 1 ATOM 4163 N N . GLY D 2 41 ? 12.840 21.872 -23.680 1.00 63.70 ? 211 GLY D N 1 ATOM 4164 C CA . GLY D 2 41 ? 11.873 21.710 -24.760 1.00 64.71 ? 211 GLY D CA 1 ATOM 4165 C C . GLY D 2 41 ? 12.325 22.499 -25.978 1.00 66.36 ? 211 GLY D C 1 ATOM 4166 O O . GLY D 2 41 ? 13.489 22.411 -26.387 1.00 66.75 ? 211 GLY D O 1 ATOM 4167 N N . SER D 2 42 ? 11.410 23.284 -26.544 1.00 66.94 ? 212 SER D N 1 ATOM 4168 C CA . SER D 2 42 ? 11.720 24.154 -27.678 1.00 67.19 ? 212 SER D CA 1 ATOM 4169 C C . SER D 2 42 ? 11.662 25.638 -27.304 1.00 67.94 ? 212 SER D C 1 ATOM 4170 O O . SER D 2 42 ? 11.322 26.484 -28.140 1.00 67.67 ? 212 SER D O 1 ATOM 4171 C CB . SER D 2 42 ? 10.784 23.858 -28.856 1.00 67.54 ? 212 SER D CB 1 ATOM 4172 O OG . SER D 2 42 ? 9.426 23.811 -28.453 1.00 66.84 ? 212 SER D OG 1 ATOM 4173 N N . SER D 2 43 ? 12.004 25.944 -26.052 1.00 68.30 ? 213 SER D N 1 ATOM 4174 C CA . SER D 2 43 ? 12.008 27.324 -25.558 1.00 69.10 ? 213 SER D CA 1 ATOM 4175 C C . SER D 2 43 ? 13.229 27.630 -24.681 1.00 68.92 ? 213 SER D C 1 ATOM 4176 O O . SER D 2 43 ? 13.469 26.958 -23.675 1.00 69.09 ? 213 SER D O 1 ATOM 4177 C CB . SER D 2 43 ? 10.702 27.640 -24.814 1.00 69.53 ? 213 SER D CB 1 ATOM 4178 O OG . SER D 2 43 ? 10.495 26.751 -23.730 1.00 69.89 ? 213 SER D OG 1 ATOM 4179 N N . THR D 2 44 ? 13.992 28.648 -25.073 1.00 68.69 ? 214 THR D N 1 ATOM 4180 C CA . THR D 2 44 ? 15.235 28.997 -24.384 1.00 69.02 ? 214 THR D CA 1 ATOM 4181 C C . THR D 2 44 ? 14.958 29.591 -22.999 1.00 69.06 ? 214 THR D C 1 ATOM 4182 O O . THR D 2 44 ? 14.597 30.761 -22.863 1.00 69.80 ? 214 THR D O 1 ATOM 4183 C CB . THR D 2 44 ? 16.141 29.928 -25.242 1.00 68.91 ? 214 THR D CB 1 ATOM 4184 O OG1 . THR D 2 44 ? 16.361 29.330 -26.524 1.00 68.82 ? 214 THR D OG1 1 ATOM 4185 C CG2 . THR D 2 44 ? 17.492 30.152 -24.569 1.00 68.44 ? 214 THR D CG2 1 ATOM 4186 N N . LEU D 2 45 ? 15.132 28.751 -21.983 1.00 68.55 ? 215 LEU D N 1 ATOM 4187 C CA . LEU D 2 45 ? 14.871 29.106 -20.597 1.00 67.87 ? 215 LEU D CA 1 ATOM 4188 C C . LEU D 2 45 ? 16.037 29.846 -19.928 1.00 67.25 ? 215 LEU D C 1 ATOM 4189 O O . LEU D 2 45 ? 15.817 30.767 -19.140 1.00 66.89 ? 215 LEU D O 1 ATOM 4190 C CB . LEU D 2 45 ? 14.529 27.834 -19.819 1.00 68.31 ? 215 LEU D CB 1 ATOM 4191 C CG . LEU D 2 45 ? 14.390 27.866 -18.296 1.00 68.75 ? 215 LEU D CG 1 ATOM 4192 C CD1 . LEU D 2 45 ? 13.104 28.572 -17.874 1.00 69.80 ? 215 LEU D CD1 1 ATOM 4193 C CD2 . LEU D 2 45 ? 14.433 26.445 -17.753 1.00 68.27 ? 215 LEU D CD2 1 ATOM 4194 N N . LEU D 2 46 ? 17.267 29.439 -20.244 1.00 67.21 ? 216 LEU D N 1 ATOM 4195 C CA . LEU D 2 46 ? 18.471 29.950 -19.571 1.00 66.48 ? 216 LEU D CA 1 ATOM 4196 C C . LEU D 2 46 ? 19.529 30.508 -20.518 1.00 65.86 ? 216 LEU D C 1 ATOM 4197 O O . LEU D 2 46 ? 19.478 30.285 -21.729 1.00 66.10 ? 216 LEU D O 1 ATOM 4198 C CB . LEU D 2 46 ? 19.115 28.851 -18.719 1.00 66.11 ? 216 LEU D CB 1 ATOM 4199 C CG . LEU D 2 46 ? 18.450 28.411 -17.421 1.00 66.48 ? 216 LEU D CG 1 ATOM 4200 C CD1 . LEU D 2 46 ? 19.170 27.190 -16.883 1.00 66.64 ? 216 LEU D CD1 1 ATOM 4201 C CD2 . LEU D 2 46 ? 18.457 29.537 -16.397 1.00 66.40 ? 216 LEU D CD2 1 ATOM 4202 N N . CYS D 2 47 ? 20.485 31.231 -19.939 1.00 66.20 ? 217 CYS D N 1 ATOM 4203 C CA . CYS D 2 47 ? 21.669 31.724 -20.643 1.00 67.11 ? 217 CYS D CA 1 ATOM 4204 C C . CYS D 2 47 ? 21.331 32.564 -21.895 1.00 68.51 ? 217 CYS D C 1 ATOM 4205 O O . CYS D 2 47 ? 22.031 32.510 -22.915 1.00 68.01 ? 217 CYS D O 1 ATOM 4206 C CB . CYS D 2 47 ? 22.615 30.553 -20.962 1.00 66.24 ? 217 CYS D CB 1 ATOM 4207 S SG . CYS D 2 47 ? 24.273 31.041 -21.478 1.00 66.75 ? 217 CYS D SG 1 ATOM 4208 N N . GLU D 2 48 ? 20.260 33.351 -21.792 1.00 70.18 ? 218 GLU D N 1 ATOM 4209 C CA . GLU D 2 48 ? 19.761 34.165 -22.906 1.00 71.68 ? 218 GLU D CA 1 ATOM 4210 C C . GLU D 2 48 ? 20.657 35.369 -23.244 1.00 71.29 ? 218 GLU D C 1 ATOM 4211 O O . GLU D 2 48 ? 20.567 35.925 -24.341 1.00 71.87 ? 218 GLU D O 1 ATOM 4212 C CB . GLU D 2 48 ? 18.303 34.592 -22.646 1.00 73.29 ? 218 GLU D CB 1 ATOM 4213 C CG . GLU D 2 48 ? 17.659 35.520 -23.699 1.00 75.35 ? 218 GLU D CG 1 ATOM 4214 C CD . GLU D 2 48 ? 17.498 34.888 -25.088 1.00 76.69 ? 218 GLU D CD 1 ATOM 4215 O OE1 . GLU D 2 48 ? 16.380 34.988 -25.654 1.00 76.38 ? 218 GLU D OE1 1 ATOM 4216 O OE2 . GLU D 2 48 ? 18.479 34.307 -25.619 1.00 76.72 ? 218 GLU D OE2 1 ATOM 4217 N N . ASP D 2 49 ? 21.522 35.764 -22.314 1.00 70.67 ? 219 ASP D N 1 ATOM 4218 C CA . ASP D 2 49 ? 22.476 36.849 -22.568 1.00 70.47 ? 219 ASP D CA 1 ATOM 4219 C C . ASP D 2 49 ? 23.914 36.337 -22.708 1.00 68.22 ? 219 ASP D C 1 ATOM 4220 O O . ASP D 2 49 ? 24.867 37.122 -22.747 1.00 67.31 ? 219 ASP D O 1 ATOM 4221 C CB . ASP D 2 49 ? 22.376 37.916 -21.470 1.00 72.40 ? 219 ASP D CB 1 ATOM 4222 C CG . ASP D 2 49 ? 21.050 38.658 -21.499 1.00 73.77 ? 219 ASP D CG 1 ATOM 4223 O OD1 . ASP D 2 49 ? 20.716 39.232 -22.562 1.00 74.13 ? 219 ASP D OD1 1 ATOM 4224 O OD2 . ASP D 2 49 ? 20.346 38.668 -20.461 1.00 73.98 ? 219 ASP D OD2 1 ATOM 4225 N N . GLY D 2 50 ? 24.053 35.014 -22.785 1.00 65.91 ? 220 GLY D N 1 ATOM 4226 C CA . GLY D 2 50 ? 25.353 34.377 -22.927 1.00 63.03 ? 220 GLY D CA 1 ATOM 4227 C C . GLY D 2 50 ? 26.004 34.038 -21.602 1.00 61.05 ? 220 GLY D C 1 ATOM 4228 O O . GLY D 2 50 ? 26.043 34.855 -20.684 1.00 61.49 ? 220 GLY D O 1 ATOM 4229 N N . CYS D 2 51 ? 26.504 32.814 -21.506 1.00 59.44 ? 221 CYS D N 1 ATOM 4230 C CA . CYS D 2 51 ? 27.289 32.375 -20.363 1.00 57.99 ? 221 CYS D CA 1 ATOM 4231 C C . CYS D 2 51 ? 28.520 31.621 -20.867 1.00 54.93 ? 221 CYS D C 1 ATOM 4232 O O . CYS D 2 51 ? 28.741 31.531 -22.075 1.00 54.52 ? 221 CYS D O 1 ATOM 4233 C CB . CYS D 2 51 ? 26.442 31.536 -19.395 1.00 60.47 ? 221 CYS D CB 1 ATOM 4234 S SG . CYS D 2 51 ? 25.506 30.163 -20.123 1.00 63.87 ? 221 CYS D SG 1 ATOM 4235 N N . LEU D 2 52 ? 29.338 31.118 -19.946 1.00 51.73 ? 222 LEU D N 1 ATOM 4236 C CA . LEU D 2 52 ? 30.546 30.385 -20.309 1.00 48.03 ? 222 LEU D CA 1 ATOM 4237 C C . LEU D 2 52 ? 30.354 28.880 -20.138 1.00 44.39 ? 222 LEU D C 1 ATOM 4238 O O . LEU D 2 52 ? 29.603 28.437 -19.275 1.00 42.58 ? 222 LEU D O 1 ATOM 4239 C CB . LEU D 2 52 ? 31.740 30.859 -19.479 1.00 49.02 ? 222 LEU D CB 1 ATOM 4240 C CG . LEU D 2 52 ? 32.065 32.355 -19.382 1.00 50.02 ? 222 LEU D CG 1 ATOM 4241 C CD1 . LEU D 2 52 ? 33.337 32.562 -18.586 1.00 49.88 ? 222 LEU D CD1 1 ATOM 4242 C CD2 . LEU D 2 52 ? 32.190 33.009 -20.755 1.00 50.36 ? 222 LEU D CD2 1 ATOM 4243 N N . ALA D 2 53 ? 31.032 28.101 -20.975 1.00 41.59 ? 223 ALA D N 1 ATOM 4244 C CA . ALA D 2 53 ? 30.998 26.653 -20.869 1.00 39.27 ? 223 ALA D CA 1 ATOM 4245 C C . ALA D 2 53 ? 32.414 26.121 -20.895 1.00 38.46 ? 223 ALA D C 1 ATOM 4246 O O . ALA D 2 53 ? 33.094 26.201 -21.917 1.00 39.32 ? 223 ALA D O 1 ATOM 4247 C CB . ALA D 2 53 ? 30.168 26.041 -21.997 1.00 39.46 ? 223 ALA D CB 1 ATOM 4248 N N . LEU D 2 54 ? 32.865 25.609 -19.754 1.00 37.30 ? 224 LEU D N 1 ATOM 4249 C CA . LEU D 2 54 ? 34.131 24.896 -19.670 1.00 35.90 ? 224 LEU D CA 1 ATOM 4250 C C . LEU D 2 54 ? 33.907 23.486 -20.211 1.00 34.76 ? 224 LEU D C 1 ATOM 4251 O O . LEU D 2 54 ? 32.903 22.858 -19.887 1.00 36.85 ? 224 LEU D O 1 ATOM 4252 C CB . LEU D 2 54 ? 34.598 24.850 -18.212 1.00 36.86 ? 224 LEU D CB 1 ATOM 4253 C CG . LEU D 2 54 ? 35.972 24.280 -17.855 1.00 37.74 ? 224 LEU D CG 1 ATOM 4254 C CD1 . LEU D 2 54 ? 37.092 25.235 -18.255 1.00 37.03 ? 224 LEU D CD1 1 ATOM 4255 C CD2 . LEU D 2 54 ? 36.045 23.954 -16.359 1.00 36.54 ? 224 LEU D CD2 1 ATOM 4256 N N . VAL D 2 55 ? 34.809 22.995 -21.058 1.00 33.53 ? 225 VAL D N 1 ATOM 4257 C CA . VAL D 2 55 ? 34.714 21.611 -21.525 1.00 32.08 ? 225 VAL D CA 1 ATOM 4258 C C . VAL D 2 55 ? 35.737 20.756 -20.775 1.00 33.04 ? 225 VAL D C 1 ATOM 4259 O O . VAL D 2 55 ? 36.925 20.729 -21.114 1.00 33.09 ? 225 VAL D O 1 ATOM 4260 C CB . VAL D 2 55 ? 34.833 21.492 -23.053 1.00 31.33 ? 225 VAL D CB 1 ATOM 4261 C CG1 . VAL D 2 55 ? 34.554 20.054 -23.506 1.00 29.37 ? 225 VAL D CG1 1 ATOM 4262 C CG2 . VAL D 2 55 ? 33.867 22.447 -23.722 1.00 30.97 ? 225 VAL D CG2 1 ATOM 4263 N N . ASP D 2 56 ? 35.241 20.068 -19.746 1.00 33.64 ? 226 ASP D N 1 ATOM 4264 C CA . ASP D 2 56 ? 36.062 19.479 -18.688 1.00 33.46 ? 226 ASP D CA 1 ATOM 4265 C C . ASP D 2 56 ? 35.963 17.959 -18.692 1.00 33.20 ? 226 ASP D C 1 ATOM 4266 O O . ASP D 2 56 ? 34.996 17.388 -18.174 1.00 33.87 ? 226 ASP D O 1 ATOM 4267 C CB . ASP D 2 56 ? 35.600 20.028 -17.331 1.00 34.79 ? 226 ASP D CB 1 ATOM 4268 C CG . ASP D 2 56 ? 36.558 19.689 -16.191 1.00 36.90 ? 226 ASP D CG 1 ATOM 4269 O OD1 . ASP D 2 56 ? 37.442 18.817 -16.367 1.00 36.70 ? 226 ASP D OD1 1 ATOM 4270 O OD2 . ASP D 2 56 ? 36.416 20.299 -15.106 1.00 37.69 ? 226 ASP D OD2 1 ATOM 4271 N N . THR D 2 57 ? 36.969 17.306 -19.267 1.00 31.35 ? 227 THR D N 1 ATOM 4272 C CA . THR D 2 57 ? 36.962 15.850 -19.402 1.00 28.75 ? 227 THR D CA 1 ATOM 4273 C C . THR D 2 57 ? 37.162 15.140 -18.064 1.00 27.26 ? 227 THR D C 1 ATOM 4274 O O . THR D 2 57 ? 36.962 13.932 -17.976 1.00 23.63 ? 227 THR D O 1 ATOM 4275 C CB . THR D 2 57 ? 38.035 15.352 -20.390 1.00 29.67 ? 227 THR D CB 1 ATOM 4276 O OG1 . THR D 2 57 ? 39.342 15.761 -19.946 1.00 29.19 ? 227 THR D OG1 1 ATOM 4277 C CG2 . THR D 2 57 ? 37.773 15.889 -21.779 1.00 29.29 ? 227 THR D CG2 1 ATOM 4278 N N . GLY D 2 58 ? 37.555 15.902 -17.040 1.00 27.09 ? 228 GLY D N 1 ATOM 4279 C CA . GLY D 2 58 ? 37.724 15.376 -15.689 1.00 28.27 ? 228 GLY D CA 1 ATOM 4280 C C . GLY D 2 58 ? 36.477 15.468 -14.833 1.00 27.79 ? 228 GLY D C 1 ATOM 4281 O O . GLY D 2 58 ? 36.389 14.816 -13.801 1.00 28.89 ? 228 GLY D O 1 ATOM 4282 N N . ALA D 2 59 ? 35.511 16.279 -15.257 1.00 27.98 ? 229 ALA D N 1 ATOM 4283 C CA . ALA D 2 59 ? 34.229 16.380 -14.558 1.00 26.73 ? 229 ALA D CA 1 ATOM 4284 C C . ALA D 2 59 ? 33.310 15.218 -14.917 1.00 28.08 ? 229 ALA D C 1 ATOM 4285 O O . ALA D 2 59 ? 33.302 14.733 -16.057 1.00 29.69 ? 229 ALA D O 1 ATOM 4286 C CB . ALA D 2 59 ? 33.556 17.697 -14.875 1.00 26.47 ? 229 ALA D CB 1 ATOM 4287 N N . SER D 2 60 ? 32.527 14.783 -13.941 1.00 28.07 ? 230 SER D N 1 ATOM 4288 C CA . SER D 2 60 ? 31.614 13.680 -14.128 1.00 29.52 ? 230 SER D CA 1 ATOM 4289 C C . SER D 2 60 ? 30.336 14.111 -14.829 1.00 30.63 ? 230 SER D C 1 ATOM 4290 O O . SER D 2 60 ? 29.767 13.341 -15.606 1.00 31.22 ? 230 SER D O 1 ATOM 4291 C CB . SER D 2 60 ? 31.258 13.043 -12.779 1.00 30.43 ? 230 SER D CB 1 ATOM 4292 O OG . SER D 2 60 ? 32.326 12.262 -12.283 1.00 31.18 ? 230 SER D OG 1 ATOM 4293 N N . TYR D 2 61 ? 29.886 15.332 -14.552 1.00 31.28 ? 231 TYR D N 1 ATOM 4294 C CA . TYR D 2 61 ? 28.555 15.764 -14.970 1.00 33.88 ? 231 TYR D CA 1 ATOM 4295 C C . TYR D 2 61 ? 28.591 17.009 -15.839 1.00 35.09 ? 231 TYR D C 1 ATOM 4296 O O . TYR D 2 61 ? 29.659 17.546 -16.103 1.00 32.87 ? 231 TYR D O 1 ATOM 4297 C CB . TYR D 2 61 ? 27.673 16.003 -13.734 1.00 35.54 ? 231 TYR D CB 1 ATOM 4298 C CG . TYR D 2 61 ? 27.735 14.852 -12.759 1.00 36.22 ? 231 TYR D CG 1 ATOM 4299 C CD1 . TYR D 2 61 ? 27.129 13.641 -13.057 1.00 35.15 ? 231 TYR D CD1 1 ATOM 4300 C CD2 . TYR D 2 61 ? 28.448 14.962 -11.560 1.00 36.49 ? 231 TYR D CD2 1 ATOM 4301 C CE1 . TYR D 2 61 ? 27.200 12.574 -12.191 1.00 36.38 ? 231 TYR D CE1 1 ATOM 4302 C CE2 . TYR D 2 61 ? 28.531 13.891 -10.678 1.00 36.57 ? 231 TYR D CE2 1 ATOM 4303 C CZ . TYR D 2 61 ? 27.899 12.700 -11.005 1.00 36.58 ? 231 TYR D CZ 1 ATOM 4304 O OH . TYR D 2 61 ? 27.959 11.625 -10.151 1.00 37.92 ? 231 TYR D OH 1 ATOM 4305 N N . ILE D 2 62 ? 27.411 17.418 -16.315 1.00 36.45 ? 232 ILE D N 1 ATOM 4306 C CA . ILE D 2 62 ? 27.167 18.787 -16.742 1.00 38.04 ? 232 ILE D CA 1 ATOM 4307 C C . ILE D 2 62 ? 26.853 19.546 -15.455 1.00 39.32 ? 232 ILE D C 1 ATOM 4308 O O . ILE D 2 62 ? 26.041 19.083 -14.644 1.00 38.30 ? 232 ILE D O 1 ATOM 4309 C CB . ILE D 2 62 ? 25.946 18.880 -17.689 1.00 38.82 ? 232 ILE D CB 1 ATOM 4310 C CG1 . ILE D 2 62 ? 26.258 18.254 -19.047 1.00 39.07 ? 232 ILE D CG1 1 ATOM 4311 C CG2 . ILE D 2 62 ? 25.518 20.327 -17.881 1.00 39.16 ? 232 ILE D CG2 1 ATOM 4312 C CD1 . ILE D 2 62 ? 25.023 17.997 -19.904 1.00 38.79 ? 232 ILE D CD1 1 ATOM 4313 N N . SER D 2 63 ? 27.500 20.689 -15.246 1.00 40.13 ? 233 SER D N 1 ATOM 4314 C CA . SER D 2 63 ? 27.201 21.506 -14.080 1.00 41.38 ? 233 SER D CA 1 ATOM 4315 C C . SER D 2 63 ? 26.995 22.963 -14.447 1.00 43.56 ? 233 SER D C 1 ATOM 4316 O O . SER D 2 63 ? 27.533 23.444 -15.440 1.00 43.75 ? 233 SER D O 1 ATOM 4317 C CB . SER D 2 63 ? 28.288 21.371 -13.012 1.00 40.29 ? 233 SER D CB 1 ATOM 4318 O OG . SER D 2 63 ? 29.389 22.211 -13.289 1.00 39.70 ? 233 SER D OG 1 ATOM 4319 N N . GLY D 2 64 ? 26.206 23.652 -13.631 1.00 44.96 ? 234 GLY D N 1 ATOM 4320 C CA . GLY D 2 64 ? 25.988 25.087 -13.762 1.00 47.79 ? 234 GLY D CA 1 ATOM 4321 C C . GLY D 2 64 ? 25.897 25.713 -12.387 1.00 49.00 ? 234 GLY D C 1 ATOM 4322 O O . GLY D 2 64 ? 25.902 25.003 -11.382 1.00 48.97 ? 234 GLY D O 1 ATOM 4323 N N . SER D 2 65 ? 25.835 27.041 -12.338 1.00 50.92 ? 235 SER D N 1 ATOM 4324 C CA . SER D 2 65 ? 25.611 27.762 -11.078 1.00 51.97 ? 235 SER D CA 1 ATOM 4325 C C . SER D 2 65 ? 24.373 27.222 -10.366 1.00 52.44 ? 235 SER D C 1 ATOM 4326 O O . SER D 2 65 ? 23.423 26.767 -11.017 1.00 52.32 ? 235 SER D O 1 ATOM 4327 C CB . SER D 2 65 ? 25.455 29.267 -11.338 1.00 52.29 ? 235 SER D CB 1 ATOM 4328 O OG . SER D 2 65 ? 24.249 29.571 -12.029 1.00 51.84 ? 235 SER D OG 1 ATOM 4329 N N . THR D 2 66 ? 24.386 27.259 -9.036 1.00 54.68 ? 236 THR D N 1 ATOM 4330 C CA . THR D 2 66 ? 23.217 26.855 -8.233 1.00 55.97 ? 236 THR D CA 1 ATOM 4331 C C . THR D 2 66 ? 21.947 27.587 -8.702 1.00 56.44 ? 236 THR D C 1 ATOM 4332 O O . THR D 2 66 ? 20.871 26.984 -8.805 1.00 55.97 ? 236 THR D O 1 ATOM 4333 C CB . THR D 2 66 ? 23.446 27.098 -6.725 1.00 57.22 ? 236 THR D CB 1 ATOM 4334 O OG1 . THR D 2 66 ? 24.762 26.660 -6.359 1.00 57.42 ? 236 THR D OG1 1 ATOM 4335 C CG2 . THR D 2 66 ? 22.417 26.337 -5.891 1.00 57.95 ? 236 THR D CG2 1 ATOM 4336 N N . SER D 2 67 ? 22.099 28.877 -9.005 1.00 57.05 ? 237 SER D N 1 ATOM 4337 C CA . SER D 2 67 ? 21.043 29.700 -9.595 1.00 58.43 ? 237 SER D CA 1 ATOM 4338 C C . SER D 2 67 ? 20.423 29.035 -10.827 1.00 58.97 ? 237 SER D C 1 ATOM 4339 O O . SER D 2 67 ? 19.199 28.877 -10.911 1.00 59.00 ? 237 SER D O 1 ATOM 4340 C CB . SER D 2 67 ? 21.594 31.079 -9.992 1.00 59.29 ? 237 SER D CB 1 ATOM 4341 O OG . SER D 2 67 ? 22.645 31.499 -9.133 1.00 60.49 ? 237 SER D OG 1 ATOM 4342 N N . SER D 2 68 ? 21.281 28.646 -11.772 1.00 58.37 ? 238 SER D N 1 ATOM 4343 C CA . SER D 2 68 ? 20.844 28.114 -13.060 1.00 57.61 ? 238 SER D CA 1 ATOM 4344 C C . SER D 2 68 ? 20.261 26.716 -12.945 1.00 57.38 ? 238 SER D C 1 ATOM 4345 O O . SER D 2 68 ? 19.231 26.413 -13.564 1.00 55.36 ? 238 SER D O 1 ATOM 4346 C CB . SER D 2 68 ? 22.003 28.112 -14.056 1.00 57.85 ? 238 SER D CB 1 ATOM 4347 O OG . SER D 2 68 ? 22.256 29.416 -14.538 1.00 57.81 ? 238 SER D OG 1 ATOM 4348 N N . ILE D 2 69 ? 20.926 25.871 -12.154 1.00 57.64 ? 239 ILE D N 1 ATOM 4349 C CA . ILE D 2 69 ? 20.509 24.479 -11.976 1.00 58.35 ? 239 ILE D CA 1 ATOM 4350 C C . ILE D 2 69 ? 19.160 24.397 -11.259 1.00 59.56 ? 239 ILE D C 1 ATOM 4351 O O . ILE D 2 69 ? 18.370 23.483 -11.506 1.00 59.59 ? 239 ILE D O 1 ATOM 4352 C CB . ILE D 2 69 ? 21.600 23.630 -11.261 1.00 57.50 ? 239 ILE D CB 1 ATOM 4353 C CG1 . ILE D 2 69 ? 22.922 23.676 -12.041 1.00 56.67 ? 239 ILE D CG1 1 ATOM 4354 C CG2 . ILE D 2 69 ? 21.144 22.174 -11.056 1.00 56.05 ? 239 ILE D CG2 1 ATOM 4355 C CD1 . ILE D 2 69 ? 22.810 23.332 -13.517 1.00 57.14 ? 239 ILE D CD1 1 ATOM 4356 N N . GLU D 2 70 ? 18.892 25.368 -10.393 1.00 61.38 ? 240 GLU D N 1 ATOM 4357 C CA . GLU D 2 70 ? 17.583 25.465 -9.755 1.00 63.37 ? 240 GLU D CA 1 ATOM 4358 C C . GLU D 2 70 ? 16.517 25.817 -10.786 1.00 62.94 ? 240 GLU D C 1 ATOM 4359 O O . GLU D 2 70 ? 15.504 25.129 -10.884 1.00 62.14 ? 240 GLU D O 1 ATOM 4360 C CB . GLU D 2 70 ? 17.606 26.451 -8.584 1.00 64.16 ? 240 GLU D CB 1 ATOM 4361 C CG . GLU D 2 70 ? 18.169 25.827 -7.301 1.00 64.97 ? 240 GLU D CG 1 ATOM 4362 C CD . GLU D 2 70 ? 18.547 26.845 -6.233 1.00 65.13 ? 240 GLU D CD 1 ATOM 4363 O OE1 . GLU D 2 70 ? 19.090 26.421 -5.188 1.00 65.38 ? 240 GLU D OE1 1 ATOM 4364 O OE2 . GLU D 2 70 ? 18.309 28.058 -6.433 1.00 65.71 ? 240 GLU D OE2 1 ATOM 4365 N N . LYS D 2 71 ? 16.773 26.861 -11.572 1.00 63.43 ? 241 LYS D N 1 ATOM 4366 C CA . LYS D 2 71 ? 15.893 27.253 -12.672 1.00 63.51 ? 241 LYS D CA 1 ATOM 4367 C C . LYS D 2 71 ? 15.642 26.056 -13.596 1.00 63.28 ? 241 LYS D C 1 ATOM 4368 O O . LYS D 2 71 ? 14.495 25.762 -13.947 1.00 63.95 ? 241 LYS D O 1 ATOM 4369 C CB . LYS D 2 71 ? 16.530 28.389 -13.469 1.00 64.58 ? 241 LYS D CB 1 ATOM 4370 C CG . LYS D 2 71 ? 15.623 29.575 -13.762 1.00 66.23 ? 241 LYS D CG 1 ATOM 4371 C CD . LYS D 2 71 ? 16.002 30.780 -12.891 1.00 68.12 ? 241 LYS D CD 1 ATOM 4372 C CE . LYS D 2 71 ? 17.268 31.478 -13.411 1.00 68.57 ? 241 LYS D CE 1 ATOM 4373 N NZ . LYS D 2 71 ? 17.963 32.308 -12.378 1.00 68.92 ? 241 LYS D NZ 1 ATOM 4374 N N . LEU D 2 72 ? 16.723 25.363 -13.962 1.00 62.14 ? 242 LEU D N 1 ATOM 4375 C CA . LEU D 2 72 ? 16.673 24.206 -14.857 1.00 60.89 ? 242 LEU D CA 1 ATOM 4376 C C . LEU D 2 72 ? 15.851 23.044 -14.299 1.00 60.94 ? 242 LEU D C 1 ATOM 4377 O O . LEU D 2 72 ? 15.040 22.457 -15.014 1.00 60.00 ? 242 LEU D O 1 ATOM 4378 C CB . LEU D 2 72 ? 18.092 23.731 -15.191 1.00 60.17 ? 242 LEU D CB 1 ATOM 4379 C CG . LEU D 2 72 ? 18.258 22.436 -15.992 1.00 59.04 ? 242 LEU D CG 1 ATOM 4380 C CD1 . LEU D 2 72 ? 17.936 22.661 -17.459 1.00 58.70 ? 242 LEU D CD1 1 ATOM 4381 C CD2 . LEU D 2 72 ? 19.660 21.898 -15.832 1.00 59.04 ? 242 LEU D CD2 1 ATOM 4382 N N . MET D 2 73 ? 16.073 22.712 -13.031 1.00 61.80 ? 243 MET D N 1 ATOM 4383 C CA . MET D 2 73 ? 15.362 21.604 -12.385 1.00 63.83 ? 243 MET D CA 1 ATOM 4384 C C . MET D 2 73 ? 13.920 21.972 -12.024 1.00 65.66 ? 243 MET D C 1 ATOM 4385 O O . MET D 2 73 ? 13.011 21.151 -12.154 1.00 65.57 ? 243 MET D O 1 ATOM 4386 C CB . MET D 2 73 ? 16.124 21.118 -11.149 1.00 62.75 ? 243 MET D CB 1 ATOM 4387 C CG . MET D 2 73 ? 17.508 20.549 -11.452 1.00 61.55 ? 243 MET D CG 1 ATOM 4388 S SD . MET D 2 73 ? 17.450 19.048 -12.446 1.00 61.35 ? 243 MET D SD 1 ATOM 4389 C CE . MET D 2 73 ? 19.197 18.673 -12.576 1.00 62.11 ? 243 MET D CE 1 ATOM 4390 N N . GLU D 2 74 ? 13.726 23.216 -11.586 1.00 68.19 ? 244 GLU D N 1 ATOM 4391 C CA . GLU D 2 74 ? 12.404 23.774 -11.310 1.00 70.49 ? 244 GLU D CA 1 ATOM 4392 C C . GLU D 2 74 ? 11.547 23.797 -12.578 1.00 71.32 ? 244 GLU D C 1 ATOM 4393 O O . GLU D 2 74 ? 10.367 24.156 -12.533 1.00 72.35 ? 244 GLU D O 1 ATOM 4394 C CB . GLU D 2 74 ? 12.558 25.187 -10.737 1.00 72.28 ? 244 GLU D CB 1 ATOM 4395 C CG . GLU D 2 74 ? 11.502 25.616 -9.718 1.00 73.93 ? 244 GLU D CG 1 ATOM 4396 C CD . GLU D 2 74 ? 10.632 26.771 -10.201 1.00 75.22 ? 244 GLU D CD 1 ATOM 4397 O OE1 . GLU D 2 74 ? 9.593 27.037 -9.557 1.00 75.87 ? 244 GLU D OE1 1 ATOM 4398 O OE2 . GLU D 2 74 ? 10.987 27.419 -11.214 1.00 75.19 ? 244 GLU D OE2 1 ATOM 4399 N N . ALA D 2 75 ? 12.153 23.406 -13.701 1.00 71.58 ? 245 ALA D N 1 ATOM 4400 C CA . ALA D 2 75 ? 11.475 23.327 -14.998 1.00 71.60 ? 245 ALA D CA 1 ATOM 4401 C C . ALA D 2 75 ? 11.460 21.907 -15.568 1.00 71.69 ? 245 ALA D C 1 ATOM 4402 O O . ALA D 2 75 ? 10.875 21.661 -16.627 1.00 71.57 ? 245 ALA D O 1 ATOM 4403 C CB . ALA D 2 75 ? 12.120 24.284 -15.989 1.00 71.40 ? 245 ALA D CB 1 ATOM 4404 N N . LEU D 2 76 ? 12.110 20.981 -14.868 1.00 72.13 ? 246 LEU D N 1 ATOM 4405 C CA . LEU D 2 76 ? 12.121 19.579 -15.264 1.00 72.73 ? 246 LEU D CA 1 ATOM 4406 C C . LEU D 2 76 ? 11.167 18.739 -14.415 1.00 73.62 ? 246 LEU D C 1 ATOM 4407 O O . LEU D 2 76 ? 10.948 17.565 -14.701 1.00 74.12 ? 246 LEU D O 1 ATOM 4408 C CB . LEU D 2 76 ? 13.544 18.999 -15.198 1.00 72.81 ? 246 LEU D CB 1 ATOM 4409 C CG . LEU D 2 76 ? 14.573 19.380 -16.276 1.00 72.49 ? 246 LEU D CG 1 ATOM 4410 C CD1 . LEU D 2 76 ? 15.957 18.914 -15.871 1.00 72.35 ? 246 LEU D CD1 1 ATOM 4411 C CD2 . LEU D 2 76 ? 14.216 18.835 -17.654 1.00 72.28 ? 246 LEU D CD2 1 ATOM 4412 N N . GLY D 2 77 ? 10.589 19.344 -13.382 1.00 74.67 ? 247 GLY D N 1 ATOM 4413 C CA . GLY D 2 77 ? 9.741 18.609 -12.445 1.00 76.31 ? 247 GLY D CA 1 ATOM 4414 C C . GLY D 2 77 ? 10.587 17.633 -11.650 1.00 77.47 ? 247 GLY D C 1 ATOM 4415 O O . GLY D 2 77 ? 10.185 16.492 -11.412 1.00 77.97 ? 247 GLY D O 1 ATOM 4416 N N . ALA D 2 78 ? 11.770 18.098 -11.257 1.00 78.33 ? 248 ALA D N 1 ATOM 4417 C CA . ALA D 2 78 ? 12.742 17.302 -10.524 1.00 78.89 ? 248 ALA D CA 1 ATOM 4418 C C . ALA D 2 78 ? 13.002 17.933 -9.167 1.00 79.43 ? 248 ALA D C 1 ATOM 4419 O O . ALA D 2 78 ? 13.054 19.158 -9.041 1.00 79.15 ? 248 ALA D O 1 ATOM 4420 C CB . ALA D 2 78 ? 14.031 17.199 -11.314 1.00 79.01 ? 248 ALA D CB 1 ATOM 4421 N N . LYS D 2 79 ? 13.173 17.088 -8.157 1.00 80.98 ? 249 LYS D N 1 ATOM 4422 C CA . LYS D 2 79 ? 13.269 17.543 -6.771 1.00 82.59 ? 249 LYS D CA 1 ATOM 4423 C C . LYS D 2 79 ? 14.680 17.376 -6.214 1.00 82.85 ? 249 LYS D C 1 ATOM 4424 O O . LYS D 2 79 ? 15.456 16.558 -6.709 1.00 82.33 ? 249 LYS D O 1 ATOM 4425 C CB . LYS D 2 79 ? 12.228 16.819 -5.904 1.00 83.83 ? 249 LYS D CB 1 ATOM 4426 C CG . LYS D 2 79 ? 10.853 17.535 -5.758 1.00 85.14 ? 249 LYS D CG 1 ATOM 4427 C CD . LYS D 2 79 ? 10.166 17.961 -7.084 1.00 85.73 ? 249 LYS D CD 1 ATOM 4428 C CE . LYS D 2 79 ? 9.803 16.782 -8.003 1.00 86.33 ? 249 LYS D CE 1 ATOM 4429 N NZ . LYS D 2 79 ? 8.862 15.800 -7.386 1.00 86.65 ? 249 LYS D NZ 1 ATOM 4430 N N . LYS D 2 80 ? 14.997 18.152 -5.180 1.00 84.08 ? 250 LYS D N 1 ATOM 4431 C CA . LYS D 2 80 ? 16.367 18.271 -4.682 1.00 85.55 ? 250 LYS D CA 1 ATOM 4432 C C . LYS D 2 80 ? 16.674 17.420 -3.451 1.00 87.09 ? 250 LYS D C 1 ATOM 4433 O O . LYS D 2 80 ? 15.868 17.327 -2.526 1.00 87.49 ? 250 LYS D O 1 ATOM 4434 C CB . LYS D 2 80 ? 16.686 19.738 -4.382 1.00 85.08 ? 250 LYS D CB 1 ATOM 4435 C CG . LYS D 2 80 ? 18.166 20.033 -4.209 1.00 85.51 ? 250 LYS D CG 1 ATOM 4436 C CD . LYS D 2 80 ? 18.416 21.492 -3.860 1.00 85.88 ? 250 LYS D CD 1 ATOM 4437 C CE . LYS D 2 80 ? 19.907 21.789 -3.734 1.00 86.00 ? 250 LYS D CE 1 ATOM 4438 N NZ . LYS D 2 80 ? 20.513 21.177 -2.513 1.00 86.26 ? 250 LYS D NZ 1 ATOM 4439 N N . ARG D 2 81 ? 17.851 16.796 -3.467 1.00 89.11 ? 251 ARG D N 1 ATOM 4440 C CA . ARG D 2 81 ? 18.461 16.191 -2.281 1.00 90.25 ? 251 ARG D CA 1 ATOM 4441 C C . ARG D 2 81 ? 19.643 17.066 -1.852 1.00 91.42 ? 251 ARG D C 1 ATOM 4442 O O . ARG D 2 81 ? 19.798 18.188 -2.342 1.00 92.02 ? 251 ARG D O 1 ATOM 4443 C CB . ARG D 2 81 ? 18.957 14.783 -2.589 1.00 90.05 ? 251 ARG D CB 1 ATOM 4444 C CG . ARG D 2 81 ? 17.894 13.716 -2.661 1.00 89.85 ? 251 ARG D CG 1 ATOM 4445 C CD . ARG D 2 81 ? 18.529 12.449 -3.193 1.00 90.21 ? 251 ARG D CD 1 ATOM 4446 N NE . ARG D 2 81 ? 17.893 11.236 -2.691 1.00 90.27 ? 251 ARG D NE 1 ATOM 4447 C CZ . ARG D 2 81 ? 18.230 10.004 -3.062 1.00 90.12 ? 251 ARG D CZ 1 ATOM 4448 N NH1 . ARG D 2 81 ? 19.202 9.811 -3.947 1.00 89.68 ? 251 ARG D NH1 1 ATOM 4449 N NH2 . ARG D 2 81 ? 17.590 8.961 -2.551 1.00 90.10 ? 251 ARG D NH2 1 ATOM 4450 N N . LEU D 2 82 ? 20.480 16.547 -0.954 1.00 92.48 ? 252 LEU D N 1 ATOM 4451 C CA . LEU D 2 82 ? 21.639 17.295 -0.455 1.00 93.06 ? 252 LEU D CA 1 ATOM 4452 C C . LEU D 2 82 ? 22.712 17.501 -1.530 1.00 92.70 ? 252 LEU D C 1 ATOM 4453 O O . LEU D 2 82 ? 23.289 18.588 -1.639 1.00 92.97 ? 252 LEU D O 1 ATOM 4454 C CB . LEU D 2 82 ? 22.235 16.616 0.791 1.00 93.60 ? 252 LEU D CB 1 ATOM 4455 C CG . LEU D 2 82 ? 23.509 17.180 1.448 1.00 93.54 ? 252 LEU D CG 1 ATOM 4456 C CD1 . LEU D 2 82 ? 23.367 18.648 1.878 1.00 93.51 ? 252 LEU D CD1 1 ATOM 4457 C CD2 . LEU D 2 82 ? 23.929 16.310 2.632 1.00 93.55 ? 252 LEU D CD2 1 ATOM 4458 N N . PHE D 2 83 ? 22.967 16.457 -2.317 1.00 91.76 ? 253 PHE D N 1 ATOM 4459 C CA . PHE D 2 83 ? 23.986 16.506 -3.365 1.00 90.55 ? 253 PHE D CA 1 ATOM 4460 C C . PHE D 2 83 ? 23.409 16.621 -4.779 1.00 88.46 ? 253 PHE D C 1 ATOM 4461 O O . PHE D 2 83 ? 23.957 17.342 -5.617 1.00 88.38 ? 253 PHE D O 1 ATOM 4462 C CB . PHE D 2 83 ? 24.915 15.287 -3.277 1.00 92.25 ? 253 PHE D CB 1 ATOM 4463 C CG . PHE D 2 83 ? 25.745 15.239 -2.022 1.00 93.05 ? 253 PHE D CG 1 ATOM 4464 C CD1 . PHE D 2 83 ? 26.773 16.161 -1.811 1.00 93.21 ? 253 PHE D CD1 1 ATOM 4465 C CD2 . PHE D 2 83 ? 25.512 14.261 -1.058 1.00 93.23 ? 253 PHE D CD2 1 ATOM 4466 C CE1 . PHE D 2 83 ? 27.547 16.117 -0.651 1.00 93.42 ? 253 PHE D CE1 1 ATOM 4467 C CE2 . PHE D 2 83 ? 26.281 14.206 0.106 1.00 93.54 ? 253 PHE D CE2 1 ATOM 4468 C CZ . PHE D 2 83 ? 27.301 15.136 0.310 1.00 93.42 ? 253 PHE D CZ 1 ATOM 4469 N N . ASP D 2 84 ? 22.308 15.914 -5.036 1.00 85.42 ? 254 ASP D N 1 ATOM 4470 C CA . ASP D 2 84 ? 21.781 15.780 -6.395 1.00 82.85 ? 254 ASP D CA 1 ATOM 4471 C C . ASP D 2 84 ? 20.270 15.988 -6.534 1.00 80.28 ? 254 ASP D C 1 ATOM 4472 O O . ASP D 2 84 ? 19.573 16.257 -5.554 1.00 80.64 ? 254 ASP D O 1 ATOM 4473 C CB . ASP D 2 84 ? 22.199 14.432 -7.004 1.00 83.81 ? 254 ASP D CB 1 ATOM 4474 C CG . ASP D 2 84 ? 22.050 13.269 -6.035 1.00 84.11 ? 254 ASP D CG 1 ATOM 4475 O OD1 . ASP D 2 84 ? 20.986 13.151 -5.391 1.00 84.27 ? 254 ASP D OD1 1 ATOM 4476 O OD2 . ASP D 2 84 ? 23.002 12.464 -5.932 1.00 84.19 ? 254 ASP D OD2 1 ATOM 4477 N N . TYR D 2 85 ? 19.784 15.861 -7.767 1.00 76.87 ? 255 TYR D N 1 ATOM 4478 C CA . TYR D 2 85 ? 18.366 15.998 -8.084 1.00 73.58 ? 255 TYR D CA 1 ATOM 4479 C C . TYR D 2 85 ? 17.795 14.664 -8.543 1.00 71.82 ? 255 TYR D C 1 ATOM 4480 O O . TYR D 2 85 ? 18.516 13.837 -9.102 1.00 72.01 ? 255 TYR D O 1 ATOM 4481 C CB . TYR D 2 85 ? 18.163 17.071 -9.159 1.00 72.35 ? 255 TYR D CB 1 ATOM 4482 C CG . TYR D 2 85 ? 18.421 18.479 -8.664 1.00 71.94 ? 255 TYR D CG 1 ATOM 4483 C CD1 . TYR D 2 85 ? 17.363 19.306 -8.272 1.00 71.54 ? 255 TYR D CD1 1 ATOM 4484 C CD2 . TYR D 2 85 ? 19.720 18.982 -8.575 1.00 71.53 ? 255 TYR D CD2 1 ATOM 4485 C CE1 . TYR D 2 85 ? 17.593 20.601 -7.811 1.00 71.33 ? 255 TYR D CE1 1 ATOM 4486 C CE2 . TYR D 2 85 ? 19.961 20.274 -8.108 1.00 71.75 ? 255 TYR D CE2 1 ATOM 4487 C CZ . TYR D 2 85 ? 18.893 21.077 -7.729 1.00 71.64 ? 255 TYR D CZ 1 ATOM 4488 O OH . TYR D 2 85 ? 19.127 22.354 -7.270 1.00 71.77 ? 255 TYR D OH 1 ATOM 4489 N N . VAL D 2 86 ? 16.504 14.454 -8.300 1.00 70.23 ? 256 VAL D N 1 ATOM 4490 C CA . VAL D 2 86 ? 15.842 13.193 -8.653 1.00 68.75 ? 256 VAL D CA 1 ATOM 4491 C C . VAL D 2 86 ? 14.462 13.384 -9.277 1.00 67.98 ? 256 VAL D C 1 ATOM 4492 O O . VAL D 2 86 ? 13.803 14.400 -9.069 1.00 68.31 ? 256 VAL D O 1 ATOM 4493 C CB . VAL D 2 86 ? 15.697 12.242 -7.432 1.00 68.64 ? 256 VAL D CB 1 ATOM 4494 C CG1 . VAL D 2 86 ? 17.003 11.512 -7.143 1.00 68.08 ? 256 VAL D CG1 1 ATOM 4495 C CG2 . VAL D 2 86 ? 15.194 12.997 -6.198 1.00 68.84 ? 256 VAL D CG2 1 ATOM 4496 N N . VAL D 2 87 ? 14.048 12.395 -10.058 1.00 67.48 ? 257 VAL D N 1 ATOM 4497 C CA . VAL D 2 87 ? 12.681 12.288 -10.550 1.00 67.57 ? 257 VAL D CA 1 ATOM 4498 C C . VAL D 2 87 ? 12.197 10.880 -10.219 1.00 68.18 ? 257 VAL D C 1 ATOM 4499 O O . VAL D 2 87 ? 13.007 10.004 -9.906 1.00 68.81 ? 257 VAL D O 1 ATOM 4500 C CB . VAL D 2 87 ? 12.564 12.554 -12.090 1.00 67.19 ? 257 VAL D CB 1 ATOM 4501 C CG1 . VAL D 2 87 ? 12.976 13.972 -12.430 1.00 66.18 ? 257 VAL D CG1 1 ATOM 4502 C CG2 . VAL D 2 87 ? 13.372 11.537 -12.913 1.00 66.80 ? 257 VAL D CG2 1 ATOM 4503 N N . LYS D 2 88 ? 10.887 10.663 -10.263 1.00 68.45 ? 258 LYS D N 1 ATOM 4504 C CA . LYS D 2 88 ? 10.353 9.310 -10.167 1.00 68.97 ? 258 LYS D CA 1 ATOM 4505 C C . LYS D 2 88 ? 10.790 8.555 -11.418 1.00 67.70 ? 258 LYS D C 1 ATOM 4506 O O . LYS D 2 88 ? 10.547 9.008 -12.537 1.00 67.98 ? 258 LYS D O 1 ATOM 4507 C CB . LYS D 2 88 ? 8.824 9.330 -10.052 1.00 70.69 ? 258 LYS D CB 1 ATOM 4508 C CG . LYS D 2 88 ? 8.276 9.494 -8.627 1.00 71.92 ? 258 LYS D CG 1 ATOM 4509 C CD . LYS D 2 88 ? 7.031 10.398 -8.584 1.00 72.55 ? 258 LYS D CD 1 ATOM 4510 C CE . LYS D 2 88 ? 5.918 9.958 -9.553 1.00 73.23 ? 258 LYS D CE 1 ATOM 4511 N NZ . LYS D 2 88 ? 5.163 8.753 -9.097 1.00 72.50 ? 258 LYS D NZ 1 ATOM 4512 N N . CYS D 2 89 ? 11.447 7.415 -11.223 1.00 66.28 ? 259 CYS D N 1 ATOM 4513 C CA . CYS D 2 89 ? 11.987 6.622 -12.330 1.00 65.38 ? 259 CYS D CA 1 ATOM 4514 C C . CYS D 2 89 ? 11.007 6.425 -13.489 1.00 65.37 ? 259 CYS D C 1 ATOM 4515 O O . CYS D 2 89 ? 11.417 6.391 -14.651 1.00 65.01 ? 259 CYS D O 1 ATOM 4516 C CB . CYS D 2 89 ? 12.509 5.277 -11.821 1.00 65.20 ? 259 CYS D CB 1 ATOM 4517 S SG . CYS D 2 89 ? 13.996 5.414 -10.785 1.00 65.36 ? 259 CYS D SG 1 ATOM 4518 N N . ASN D 2 90 ? 9.718 6.317 -13.172 1.00 65.73 ? 260 ASN D N 1 ATOM 4519 C CA . ASN D 2 90 ? 8.679 6.113 -14.185 1.00 66.56 ? 260 ASN D CA 1 ATOM 4520 C C . ASN D 2 90 ? 8.462 7.323 -15.097 1.00 67.16 ? 260 ASN D C 1 ATOM 4521 O O . ASN D 2 90 ? 8.095 7.166 -16.265 1.00 66.73 ? 260 ASN D O 1 ATOM 4522 C CB . ASN D 2 90 ? 7.354 5.686 -13.535 1.00 66.65 ? 260 ASN D CB 1 ATOM 4523 C CG . ASN D 2 90 ? 6.651 6.832 -12.821 1.00 66.65 ? 260 ASN D CG 1 ATOM 4524 O OD1 . ASN D 2 90 ? 7.153 7.370 -11.829 1.00 66.53 ? 260 ASN D OD1 1 ATOM 4525 N ND2 . ASN D 2 90 ? 5.480 7.212 -13.327 1.00 66.06 ? 260 ASN D ND2 1 ATOM 4526 N N . GLU D 2 91 ? 8.689 8.521 -14.559 1.00 68.88 ? 261 GLU D N 1 ATOM 4527 C CA . GLU D 2 91 ? 8.494 9.763 -15.318 1.00 71.11 ? 261 GLU D CA 1 ATOM 4528 C C . GLU D 2 91 ? 9.781 10.240 -16.015 1.00 70.96 ? 261 GLU D C 1 ATOM 4529 O O . GLU D 2 91 ? 9.777 11.245 -16.736 1.00 70.98 ? 261 GLU D O 1 ATOM 4530 C CB . GLU D 2 91 ? 7.889 10.860 -14.428 1.00 71.85 ? 261 GLU D CB 1 ATOM 4531 C CG . GLU D 2 91 ? 8.791 11.353 -13.293 1.00 72.89 ? 261 GLU D CG 1 ATOM 4532 C CD . GLU D 2 91 ? 8.034 12.101 -12.198 1.00 73.10 ? 261 GLU D CD 1 ATOM 4533 O OE1 . GLU D 2 91 ? 6.782 12.138 -12.246 1.00 73.09 ? 261 GLU D OE1 1 ATOM 4534 O OE2 . GLU D 2 91 ? 8.701 12.646 -11.285 1.00 73.65 ? 261 GLU D OE2 1 ATOM 4535 N N . GLY D 2 92 ? 10.872 9.505 -15.794 1.00 70.74 ? 262 GLY D N 1 ATOM 4536 C CA . GLY D 2 92 ? 12.155 9.774 -16.441 1.00 69.65 ? 262 GLY D CA 1 ATOM 4537 C C . GLY D 2 92 ? 12.052 9.936 -17.951 1.00 68.78 ? 262 GLY D C 1 ATOM 4538 O O . GLY D 2 92 ? 12.359 11.008 -18.473 1.00 69.62 ? 262 GLY D O 1 ATOM 4539 N N . PRO D 2 93 ? 11.609 8.879 -18.663 1.00 67.29 ? 263 PRO D N 1 ATOM 4540 C CA . PRO D 2 93 ? 11.541 8.910 -20.130 1.00 66.60 ? 263 PRO D CA 1 ATOM 4541 C C . PRO D 2 93 ? 10.699 10.046 -20.721 1.00 66.35 ? 263 PRO D C 1 ATOM 4542 O O . PRO D 2 93 ? 10.936 10.443 -21.866 1.00 66.88 ? 263 PRO D O 1 ATOM 4543 C CB . PRO D 2 93 ? 10.919 7.554 -20.479 1.00 66.48 ? 263 PRO D CB 1 ATOM 4544 C CG . PRO D 2 93 ? 11.256 6.680 -19.322 1.00 66.83 ? 263 PRO D CG 1 ATOM 4545 C CD . PRO D 2 93 ? 11.168 7.577 -18.130 1.00 66.85 ? 263 PRO D CD 1 ATOM 4546 N N . THR D 2 94 ? 9.741 10.563 -19.950 1.00 65.71 ? 264 THR D N 1 ATOM 4547 C CA . THR D 2 94 ? 8.821 11.609 -20.429 1.00 64.47 ? 264 THR D CA 1 ATOM 4548 C C . THR D 2 94 ? 9.415 13.022 -20.362 1.00 63.10 ? 264 THR D C 1 ATOM 4549 O O . THR D 2 94 ? 8.897 13.950 -20.989 1.00 63.31 ? 264 THR D O 1 ATOM 4550 C CB . THR D 2 94 ? 7.468 11.588 -19.672 1.00 64.97 ? 264 THR D CB 1 ATOM 4551 O OG1 . THR D 2 94 ? 7.644 12.079 -18.335 1.00 64.07 ? 264 THR D OG1 1 ATOM 4552 C CG2 . THR D 2 94 ? 6.885 10.175 -19.639 1.00 65.84 ? 264 THR D CG2 1 ATOM 4553 N N . LEU D 2 95 ? 10.500 13.174 -19.606 1.00 61.16 ? 265 LEU D N 1 ATOM 4554 C CA . LEU D 2 95 ? 11.194 14.459 -19.468 1.00 58.64 ? 265 LEU D CA 1 ATOM 4555 C C . LEU D 2 95 ? 11.641 15.061 -20.805 1.00 56.20 ? 265 LEU D C 1 ATOM 4556 O O . LEU D 2 95 ? 11.969 14.327 -21.735 1.00 55.37 ? 265 LEU D O 1 ATOM 4557 C CB . LEU D 2 95 ? 12.391 14.322 -18.523 1.00 57.88 ? 265 LEU D CB 1 ATOM 4558 C CG . LEU D 2 95 ? 12.060 14.259 -17.038 1.00 58.57 ? 265 LEU D CG 1 ATOM 4559 C CD1 . LEU D 2 95 ? 13.321 14.406 -16.200 1.00 58.69 ? 265 LEU D CD1 1 ATOM 4560 C CD2 . LEU D 2 95 ? 11.074 15.346 -16.691 1.00 59.66 ? 265 LEU D CD2 1 ATOM 4561 N N . PRO D 2 96 ? 11.664 16.405 -20.893 1.00 55.46 ? 266 PRO D N 1 ATOM 4562 C CA . PRO D 2 96 ? 11.971 17.081 -22.152 1.00 54.80 ? 266 PRO D CA 1 ATOM 4563 C C . PRO D 2 96 ? 13.471 17.125 -22.476 1.00 54.49 ? 266 PRO D C 1 ATOM 4564 O O . PRO D 2 96 ? 14.302 17.154 -21.563 1.00 54.28 ? 266 PRO D O 1 ATOM 4565 C CB . PRO D 2 96 ? 11.447 18.499 -21.914 1.00 54.73 ? 266 PRO D CB 1 ATOM 4566 C CG . PRO D 2 96 ? 11.605 18.710 -20.451 1.00 54.88 ? 266 PRO D CG 1 ATOM 4567 C CD . PRO D 2 96 ? 11.406 17.369 -19.801 1.00 54.89 ? 266 PRO D CD 1 ATOM 4568 N N . ASP D 2 97 ? 13.788 17.123 -23.774 1.00 53.06 ? 267 ASP D N 1 ATOM 4569 C CA . ASP D 2 97 ? 15.137 17.386 -24.280 1.00 50.93 ? 267 ASP D CA 1 ATOM 4570 C C . ASP D 2 97 ? 15.733 18.657 -23.679 1.00 50.77 ? 267 ASP D C 1 ATOM 4571 O O . ASP D 2 97 ? 15.013 19.633 -23.433 1.00 52.08 ? 267 ASP D O 1 ATOM 4572 C CB . ASP D 2 97 ? 15.095 17.569 -25.799 1.00 50.27 ? 267 ASP D CB 1 ATOM 4573 C CG . ASP D 2 97 ? 14.802 16.285 -26.549 1.00 50.02 ? 267 ASP D CG 1 ATOM 4574 O OD1 . ASP D 2 97 ? 14.760 15.201 -25.928 1.00 49.91 ? 267 ASP D OD1 1 ATOM 4575 O OD2 . ASP D 2 97 ? 14.612 16.366 -27.781 1.00 50.75 ? 267 ASP D OD2 1 ATOM 4576 N N . ILE D 2 98 ? 17.042 18.644 -23.445 1.00 49.38 ? 268 ILE D N 1 ATOM 4577 C CA . ILE D 2 98 ? 17.773 19.852 -23.068 1.00 48.50 ? 268 ILE D CA 1 ATOM 4578 C C . ILE D 2 98 ? 18.779 20.203 -24.182 1.00 47.85 ? 268 ILE D C 1 ATOM 4579 O O . ILE D 2 98 ? 19.511 19.329 -24.656 1.00 48.05 ? 268 ILE D O 1 ATOM 4580 C CB . ILE D 2 98 ? 18.451 19.693 -21.688 1.00 48.85 ? 268 ILE D CB 1 ATOM 4581 C CG1 . ILE D 2 98 ? 17.382 19.578 -20.594 1.00 49.78 ? 268 ILE D CG1 1 ATOM 4582 C CG2 . ILE D 2 98 ? 19.384 20.862 -21.390 1.00 48.86 ? 268 ILE D CG2 1 ATOM 4583 C CD1 . ILE D 2 98 ? 17.897 19.071 -19.248 1.00 50.31 ? 268 ILE D CD1 1 ATOM 4584 N N . SER D 2 99 ? 18.789 21.470 -24.606 1.00 45.50 ? 269 SER D N 1 ATOM 4585 C CA . SER D 2 99 ? 19.663 21.934 -25.687 1.00 43.39 ? 269 SER D CA 1 ATOM 4586 C C . SER D 2 99 ? 20.669 22.993 -25.237 1.00 43.04 ? 269 SER D C 1 ATOM 4587 O O . SER D 2 99 ? 20.330 23.942 -24.524 1.00 40.95 ? 269 SER D O 1 ATOM 4588 C CB . SER D 2 99 ? 18.845 22.455 -26.870 1.00 44.31 ? 269 SER D CB 1 ATOM 4589 O OG . SER D 2 99 ? 18.254 21.382 -27.598 1.00 45.20 ? 269 SER D OG 1 ATOM 4590 N N . PHE D 2 100 ? 21.920 22.812 -25.646 1.00 41.44 ? 270 PHE D N 1 ATOM 4591 C CA . PHE D 2 100 ? 22.961 23.791 -25.373 1.00 40.76 ? 270 PHE D CA 1 ATOM 4592 C C . PHE D 2 100 ? 23.389 24.436 -26.688 1.00 40.41 ? 270 PHE D C 1 ATOM 4593 O O . PHE D 2 100 ? 23.716 23.734 -27.646 1.00 39.35 ? 270 PHE D O 1 ATOM 4594 C CB . PHE D 2 100 ? 24.151 23.130 -24.677 1.00 39.95 ? 270 PHE D CB 1 ATOM 4595 C CG . PHE D 2 100 ? 23.806 22.468 -23.366 1.00 40.50 ? 270 PHE D CG 1 ATOM 4596 C CD1 . PHE D 2 100 ? 23.952 23.156 -22.164 1.00 39.27 ? 270 PHE D CD1 1 ATOM 4597 C CD2 . PHE D 2 100 ? 23.356 21.147 -23.331 1.00 39.97 ? 270 PHE D CD2 1 ATOM 4598 C CE1 . PHE D 2 100 ? 23.652 22.543 -20.949 1.00 39.03 ? 270 PHE D CE1 1 ATOM 4599 C CE2 . PHE D 2 100 ? 23.052 20.528 -22.123 1.00 38.99 ? 270 PHE D CE2 1 ATOM 4600 C CZ . PHE D 2 100 ? 23.198 21.222 -20.933 1.00 39.27 ? 270 PHE D CZ 1 ATOM 4601 N N . HIS D 2 101 ? 23.380 25.768 -26.724 1.00 41.44 ? 271 HIS D N 1 ATOM 4602 C CA . HIS D 2 101 ? 23.678 26.530 -27.941 1.00 42.96 ? 271 HIS D CA 1 ATOM 4603 C C . HIS D 2 101 ? 25.141 26.969 -27.987 1.00 41.01 ? 271 HIS D C 1 ATOM 4604 O O . HIS D 2 101 ? 25.542 27.944 -27.349 1.00 41.42 ? 271 HIS D O 1 ATOM 4605 C CB . HIS D 2 101 ? 22.722 27.727 -28.079 1.00 46.61 ? 271 HIS D CB 1 ATOM 4606 C CG . HIS D 2 101 ? 22.709 28.351 -29.445 1.00 49.62 ? 271 HIS D CG 1 ATOM 4607 N ND1 . HIS D 2 101 ? 22.224 29.621 -29.674 1.00 51.55 ? 271 HIS D ND1 1 ATOM 4608 C CD2 . HIS D 2 101 ? 23.120 27.886 -30.650 1.00 51.32 ? 271 HIS D CD2 1 ATOM 4609 C CE1 . HIS D 2 101 ? 22.333 29.910 -30.960 1.00 51.96 ? 271 HIS D CE1 1 ATOM 4610 N NE2 . HIS D 2 101 ? 22.877 28.875 -31.574 1.00 51.79 ? 271 HIS D NE2 1 ATOM 4611 N N . LEU D 2 102 ? 25.932 26.231 -28.757 1.00 39.32 ? 272 LEU D N 1 ATOM 4612 C CA . LEU D 2 102 ? 27.361 26.455 -28.835 1.00 37.49 ? 272 LEU D CA 1 ATOM 4613 C C . LEU D 2 102 ? 27.744 26.669 -30.291 1.00 38.03 ? 272 LEU D C 1 ATOM 4614 O O . LEU D 2 102 ? 27.518 25.796 -31.129 1.00 36.47 ? 272 LEU D O 1 ATOM 4615 C CB . LEU D 2 102 ? 28.101 25.254 -28.237 1.00 36.68 ? 272 LEU D CB 1 ATOM 4616 C CG . LEU D 2 102 ? 27.681 24.808 -26.826 1.00 36.28 ? 272 LEU D CG 1 ATOM 4617 C CD1 . LEU D 2 102 ? 28.038 23.343 -26.554 1.00 35.93 ? 272 LEU D CD1 1 ATOM 4618 C CD2 . LEU D 2 102 ? 28.274 25.709 -25.755 1.00 35.10 ? 272 LEU D CD2 1 ATOM 4619 N N . GLY D 2 103 ? 28.302 27.841 -30.592 1.00 40.02 ? 273 GLY D N 1 ATOM 4620 C CA . GLY D 2 103 ? 28.644 28.217 -31.968 1.00 42.47 ? 273 GLY D CA 1 ATOM 4621 C C . GLY D 2 103 ? 27.459 28.152 -32.921 1.00 45.05 ? 273 GLY D C 1 ATOM 4622 O O . GLY D 2 103 ? 26.420 28.769 -32.685 1.00 46.17 ? 273 GLY D O 1 ATOM 4623 N N . GLY D 2 104 ? 27.605 27.381 -33.990 1.00 47.18 ? 274 GLY D N 1 ATOM 4624 C CA . GLY D 2 104 ? 26.550 27.267 -34.996 1.00 50.78 ? 274 GLY D CA 1 ATOM 4625 C C . GLY D 2 104 ? 25.725 25.991 -34.949 1.00 51.89 ? 274 GLY D C 1 ATOM 4626 O O . GLY D 2 104 ? 25.390 25.429 -36.001 1.00 52.68 ? 274 GLY D O 1 ATOM 4627 N N . LYS D 2 105 ? 25.378 25.553 -33.736 1.00 51.08 ? 275 LYS D N 1 ATOM 4628 C CA . LYS D 2 105 ? 24.642 24.305 -33.527 1.00 49.86 ? 275 LYS D CA 1 ATOM 4629 C C . LYS D 2 105 ? 23.895 24.314 -32.183 1.00 48.75 ? 275 LYS D C 1 ATOM 4630 O O . LYS D 2 105 ? 24.340 24.939 -31.216 1.00 49.35 ? 275 LYS D O 1 ATOM 4631 C CB . LYS D 2 105 ? 25.602 23.101 -33.661 1.00 50.58 ? 275 LYS D CB 1 ATOM 4632 C CG . LYS D 2 105 ? 25.007 21.681 -33.453 1.00 51.02 ? 275 LYS D CG 1 ATOM 4633 C CD . LYS D 2 105 ? 25.583 20.681 -34.476 1.00 52.08 ? 275 LYS D CD 1 ATOM 4634 C CE . LYS D 2 105 ? 25.656 19.227 -33.968 1.00 52.33 ? 275 LYS D CE 1 ATOM 4635 N NZ . LYS D 2 105 ? 24.422 18.698 -33.318 1.00 51.26 ? 275 LYS D NZ 1 ATOM 4636 N N . GLU D 2 106 ? 22.727 23.671 -32.151 1.00 47.32 ? 276 GLU D N 1 ATOM 4637 C CA . GLU D 2 106 ? 22.087 23.297 -30.889 1.00 45.53 ? 276 GLU D CA 1 ATOM 4638 C C . GLU D 2 106 ? 22.515 21.873 -30.550 1.00 42.66 ? 276 GLU D C 1 ATOM 4639 O O . GLU D 2 106 ? 22.366 20.952 -31.364 1.00 42.05 ? 276 GLU D O 1 ATOM 4640 C CB . GLU D 2 106 ? 20.552 23.392 -30.951 1.00 46.83 ? 276 GLU D CB 1 ATOM 4641 C CG . GLU D 2 106 ? 19.977 24.800 -31.166 1.00 48.85 ? 276 GLU D CG 1 ATOM 4642 C CD . GLU D 2 106 ? 19.983 25.695 -29.919 1.00 51.16 ? 276 GLU D CD 1 ATOM 4643 O OE1 . GLU D 2 106 ? 20.101 25.188 -28.776 1.00 51.58 ? 276 GLU D OE1 1 ATOM 4644 O OE2 . GLU D 2 106 ? 19.854 26.929 -30.092 1.00 52.30 ? 276 GLU D OE2 1 ATOM 4645 N N . TYR D 2 107 ? 23.051 21.710 -29.346 1.00 39.90 ? 277 TYR D N 1 ATOM 4646 C CA . TYR D 2 107 ? 23.474 20.411 -28.835 1.00 37.95 ? 277 TYR D CA 1 ATOM 4647 C C . TYR D 2 107 ? 22.435 19.887 -27.851 1.00 37.61 ? 277 TYR D C 1 ATOM 4648 O O . TYR D 2 107 ? 22.270 20.431 -26.762 1.00 38.32 ? 277 TYR D O 1 ATOM 4649 C CB . TYR D 2 107 ? 24.876 20.526 -28.219 1.00 34.72 ? 277 TYR D CB 1 ATOM 4650 C CG . TYR D 2 107 ? 25.907 20.797 -29.283 1.00 33.64 ? 277 TYR D CG 1 ATOM 4651 C CD1 . TYR D 2 107 ? 26.451 19.749 -30.023 1.00 33.80 ? 277 TYR D CD1 1 ATOM 4652 C CD2 . TYR D 2 107 ? 26.294 22.101 -29.604 1.00 32.93 ? 277 TYR D CD2 1 ATOM 4653 C CE1 . TYR D 2 107 ? 27.370 19.984 -31.024 1.00 32.93 ? 277 TYR D CE1 1 ATOM 4654 C CE2 . TYR D 2 107 ? 27.220 22.342 -30.605 1.00 32.42 ? 277 TYR D CE2 1 ATOM 4655 C CZ . TYR D 2 107 ? 27.750 21.277 -31.310 1.00 33.34 ? 277 TYR D CZ 1 ATOM 4656 O OH . TYR D 2 107 ? 28.662 21.485 -32.318 1.00 34.52 ? 277 TYR D OH 1 ATOM 4657 N N . THR D 2 108 ? 21.722 18.843 -28.261 1.00 37.33 ? 278 THR D N 1 ATOM 4658 C CA . THR D 2 108 ? 20.557 18.350 -27.532 1.00 37.84 ? 278 THR D CA 1 ATOM 4659 C C . THR D 2 108 ? 20.831 17.049 -26.797 1.00 38.00 ? 278 THR D C 1 ATOM 4660 O O . THR D 2 108 ? 21.277 16.061 -27.399 1.00 38.63 ? 278 THR D O 1 ATOM 4661 C CB . THR D 2 108 ? 19.318 18.125 -28.478 1.00 38.89 ? 278 THR D CB 1 ATOM 4662 O OG1 . THR D 2 108 ? 18.966 19.350 -29.136 1.00 39.25 ? 278 THR D OG1 1 ATOM 4663 C CG2 . THR D 2 108 ? 18.110 17.630 -27.685 1.00 38.18 ? 278 THR D CG2 1 ATOM 4664 N N . LEU D 2 109 ? 20.544 17.051 -25.497 1.00 37.51 ? 279 LEU D N 1 ATOM 4665 C CA . LEU D 2 109 ? 20.517 15.828 -24.706 1.00 36.87 ? 279 LEU D CA 1 ATOM 4666 C C . LEU D 2 109 ? 19.065 15.446 -24.429 1.00 39.61 ? 279 LEU D C 1 ATOM 4667 O O . LEU D 2 109 ? 18.277 16.258 -23.926 1.00 40.00 ? 279 LEU D O 1 ATOM 4668 C CB . LEU D 2 109 ? 21.290 15.994 -23.385 1.00 36.10 ? 279 LEU D CB 1 ATOM 4669 C CG . LEU D 2 109 ? 22.781 16.383 -23.287 1.00 35.48 ? 279 LEU D CG 1 ATOM 4670 C CD1 . LEU D 2 109 ? 23.485 15.470 -22.315 1.00 34.77 ? 279 LEU D CD1 1 ATOM 4671 C CD2 . LEU D 2 109 ? 23.536 16.351 -24.597 1.00 35.38 ? 279 LEU D CD2 1 ATOM 4672 N N . THR D 2 110 ? 18.706 14.216 -24.781 1.00 41.53 ? 280 THR D N 1 ATOM 4673 C CA . THR D 2 110 ? 17.395 13.670 -24.453 1.00 43.07 ? 280 THR D CA 1 ATOM 4674 C C . THR D 2 110 ? 17.471 13.177 -23.011 1.00 43.90 ? 280 THR D C 1 ATOM 4675 O O . THR D 2 110 ? 18.570 13.054 -22.464 1.00 44.29 ? 280 THR D O 1 ATOM 4676 C CB . THR D 2 110 ? 17.024 12.490 -25.372 1.00 44.84 ? 280 THR D CB 1 ATOM 4677 O OG1 . THR D 2 110 ? 17.602 11.287 -24.859 1.00 48.07 ? 280 THR D OG1 1 ATOM 4678 C CG2 . THR D 2 110 ? 17.523 12.715 -26.805 1.00 45.22 ? 280 THR D CG2 1 ATOM 4679 N N . SER D 2 111 ? 16.325 12.886 -22.397 1.00 43.48 ? 281 SER D N 1 ATOM 4680 C CA . SER D 2 111 ? 16.297 12.421 -21.005 1.00 42.62 ? 281 SER D CA 1 ATOM 4681 C C . SER D 2 111 ? 17.116 11.148 -20.776 1.00 41.71 ? 281 SER D C 1 ATOM 4682 O O . SER D 2 111 ? 17.750 11.002 -19.733 1.00 41.58 ? 281 SER D O 1 ATOM 4683 C CB . SER D 2 111 ? 14.860 12.261 -20.485 1.00 44.31 ? 281 SER D CB 1 ATOM 4684 O OG . SER D 2 111 ? 14.050 11.507 -21.370 1.00 45.01 ? 281 SER D OG 1 ATOM 4685 N N . ALA D 2 112 ? 17.121 10.246 -21.757 1.00 40.87 ? 282 ALA D N 1 ATOM 4686 C CA . ALA D 2 112 ? 17.967 9.046 -21.707 1.00 41.78 ? 282 ALA D CA 1 ATOM 4687 C C . ALA D 2 112 ? 19.477 9.359 -21.660 1.00 42.58 ? 282 ALA D C 1 ATOM 4688 O O . ALA D 2 112 ? 20.276 8.505 -21.266 1.00 42.95 ? 282 ALA D O 1 ATOM 4689 C CB . ALA D 2 112 ? 17.652 8.127 -22.881 1.00 41.07 ? 282 ALA D CB 1 ATOM 4690 N N . ASP D 2 113 ? 19.850 10.574 -22.069 1.00 42.17 ? 283 ASP D N 1 ATOM 4691 C CA . ASP D 2 113 ? 21.239 11.038 -22.037 1.00 41.66 ? 283 ASP D CA 1 ATOM 4692 C C . ASP D 2 113 ? 21.582 11.695 -20.698 1.00 41.92 ? 283 ASP D C 1 ATOM 4693 O O . ASP D 2 113 ? 22.758 11.853 -20.371 1.00 41.67 ? 283 ASP D O 1 ATOM 4694 C CB . ASP D 2 113 ? 21.519 12.031 -23.180 1.00 39.83 ? 283 ASP D CB 1 ATOM 4695 C CG . ASP D 2 113 ? 21.320 11.418 -24.552 1.00 40.83 ? 283 ASP D CG 1 ATOM 4696 O OD1 . ASP D 2 113 ? 21.915 10.357 -24.816 1.00 41.97 ? 283 ASP D OD1 1 ATOM 4697 O OD2 . ASP D 2 113 ? 20.573 11.993 -25.375 1.00 39.77 ? 283 ASP D OD2 1 ATOM 4698 N N . TYR D 2 114 ? 20.571 12.094 -19.931 1.00 41.53 ? 284 TYR D N 1 ATOM 4699 C CA . TYR D 2 114 ? 20.858 12.726 -18.638 1.00 44.41 ? 284 TYR D CA 1 ATOM 4700 C C . TYR D 2 114 ? 20.200 12.135 -17.376 1.00 44.73 ? 284 TYR D C 1 ATOM 4701 O O . TYR D 2 114 ? 20.583 12.497 -16.263 1.00 43.47 ? 284 TYR D O 1 ATOM 4702 C CB . TYR D 2 114 ? 20.686 14.252 -18.701 1.00 45.49 ? 284 TYR D CB 1 ATOM 4703 C CG . TYR D 2 114 ? 19.275 14.744 -18.894 1.00 45.88 ? 284 TYR D CG 1 ATOM 4704 C CD1 . TYR D 2 114 ? 18.421 14.918 -17.804 1.00 46.10 ? 284 TYR D CD1 1 ATOM 4705 C CD2 . TYR D 2 114 ? 18.802 15.072 -20.164 1.00 47.01 ? 284 TYR D CD2 1 ATOM 4706 C CE1 . TYR D 2 114 ? 17.120 15.380 -17.977 1.00 47.47 ? 284 TYR D CE1 1 ATOM 4707 C CE2 . TYR D 2 114 ? 17.500 15.539 -20.354 1.00 47.31 ? 284 TYR D CE2 1 ATOM 4708 C CZ . TYR D 2 114 ? 16.662 15.683 -19.255 1.00 47.25 ? 284 TYR D CZ 1 ATOM 4709 O OH . TYR D 2 114 ? 15.381 16.155 -19.427 1.00 46.81 ? 284 TYR D OH 1 ATOM 4710 N N . VAL D 2 115 ? 19.241 11.221 -17.547 1.00 45.80 ? 285 VAL D N 1 ATOM 4711 C CA . VAL D 2 115 ? 18.664 10.496 -16.408 1.00 47.85 ? 285 VAL D CA 1 ATOM 4712 C C . VAL D 2 115 ? 19.392 9.170 -16.208 1.00 48.55 ? 285 VAL D C 1 ATOM 4713 O O . VAL D 2 115 ? 19.528 8.398 -17.156 1.00 48.12 ? 285 VAL D O 1 ATOM 4714 C CB . VAL D 2 115 ? 17.145 10.167 -16.596 1.00 47.82 ? 285 VAL D CB 1 ATOM 4715 C CG1 . VAL D 2 115 ? 16.556 9.595 -15.300 1.00 49.09 ? 285 VAL D CG1 1 ATOM 4716 C CG2 . VAL D 2 115 ? 16.351 11.378 -17.060 1.00 46.72 ? 285 VAL D CG2 1 ATOM 4717 N N . PHE D 2 116 ? 19.846 8.901 -14.982 1.00 50.34 ? 286 PHE D N 1 ATOM 4718 C CA . PHE D 2 116 ? 20.324 7.558 -14.627 1.00 52.74 ? 286 PHE D CA 1 ATOM 4719 C C . PHE D 2 116 ? 19.145 6.616 -14.400 1.00 55.67 ? 286 PHE D C 1 ATOM 4720 O O . PHE D 2 116 ? 18.638 6.500 -13.285 1.00 56.62 ? 286 PHE D O 1 ATOM 4721 C CB . PHE D 2 116 ? 21.227 7.573 -13.394 1.00 50.92 ? 286 PHE D CB 1 ATOM 4722 C CG . PHE D 2 116 ? 22.593 8.131 -13.647 1.00 50.72 ? 286 PHE D CG 1 ATOM 4723 C CD1 . PHE D 2 116 ? 23.484 7.474 -14.501 1.00 50.03 ? 286 PHE D CD1 1 ATOM 4724 C CD2 . PHE D 2 116 ? 23.003 9.308 -13.017 1.00 49.84 ? 286 PHE D CD2 1 ATOM 4725 C CE1 . PHE D 2 116 ? 24.759 7.989 -14.731 1.00 50.04 ? 286 PHE D CE1 1 ATOM 4726 C CE2 . PHE D 2 116 ? 24.273 9.831 -13.240 1.00 49.71 ? 286 PHE D CE2 1 ATOM 4727 C CZ . PHE D 2 116 ? 25.155 9.171 -14.099 1.00 50.15 ? 286 PHE D CZ 1 ATOM 4728 N N . GLN D 2 117 ? 18.726 5.947 -15.471 1.00 59.60 ? 287 GLN D N 1 ATOM 4729 C CA . GLN D 2 117 ? 17.534 5.100 -15.467 1.00 63.86 ? 287 GLN D CA 1 ATOM 4730 C C . GLN D 2 117 ? 17.813 3.685 -14.937 1.00 67.35 ? 287 GLN D C 1 ATOM 4731 O O . GLN D 2 117 ? 17.961 2.730 -15.709 1.00 67.27 ? 287 GLN D O 1 ATOM 4732 C CB . GLN D 2 117 ? 16.924 5.053 -16.875 1.00 63.69 ? 287 GLN D CB 1 ATOM 4733 C CG . GLN D 2 117 ? 15.439 4.739 -16.908 1.00 64.23 ? 287 GLN D CG 1 ATOM 4734 C CD . GLN D 2 117 ? 14.594 5.858 -16.334 1.00 64.31 ? 287 GLN D CD 1 ATOM 4735 O OE1 . GLN D 2 117 ? 14.555 6.966 -16.872 1.00 64.82 ? 287 GLN D OE1 1 ATOM 4736 N NE2 . GLN D 2 117 ? 13.910 5.573 -15.236 1.00 64.27 ? 287 GLN D NE2 1 ATOM 4737 N N . GLU D 2 118 ? 17.883 3.563 -13.613 1.00 71.20 ? 288 GLU D N 1 ATOM 4738 C CA . GLU D 2 118 ? 18.111 2.274 -12.965 1.00 75.37 ? 288 GLU D CA 1 ATOM 4739 C C . GLU D 2 118 ? 16.802 1.536 -12.682 1.00 77.25 ? 288 GLU D C 1 ATOM 4740 O O . GLU D 2 118 ? 16.814 0.348 -12.357 1.00 77.93 ? 288 GLU D O 1 ATOM 4741 C CB . GLU D 2 118 ? 18.922 2.449 -11.675 1.00 76.02 ? 288 GLU D CB 1 ATOM 4742 C CG . GLU D 2 118 ? 20.410 2.731 -11.900 1.00 76.93 ? 288 GLU D CG 1 ATOM 4743 C CD . GLU D 2 118 ? 21.198 2.886 -10.602 1.00 77.41 ? 288 GLU D CD 1 ATOM 4744 O OE1 . GLU D 2 118 ? 22.383 3.288 -10.675 1.00 77.75 ? 288 GLU D OE1 1 ATOM 4745 O OE2 . GLU D 2 118 ? 20.640 2.607 -9.514 1.00 78.01 ? 288 GLU D OE2 1 ATOM 4746 N N . SER D 2 119 ? 15.680 2.242 -12.808 1.00 79.54 ? 289 SER D N 1 ATOM 4747 C CA . SER D 2 119 ? 14.358 1.651 -12.595 1.00 81.36 ? 289 SER D CA 1 ATOM 4748 C C . SER D 2 119 ? 13.310 2.222 -13.552 1.00 83.57 ? 289 SER D C 1 ATOM 4749 O O . SER D 2 119 ? 13.611 3.068 -14.398 1.00 83.70 ? 289 SER D O 1 ATOM 4750 C CB . SER D 2 119 ? 13.897 1.858 -11.147 1.00 80.77 ? 289 SER D CB 1 ATOM 4751 O OG . SER D 2 119 ? 14.819 1.322 -10.222 1.00 80.04 ? 289 SER D OG 1 ATOM 4752 N N . TYR D 2 120 ? 12.080 1.736 -13.409 1.00 85.46 ? 290 TYR D N 1 ATOM 4753 C CA . TYR D 2 120 ? 10.929 2.273 -14.122 1.00 87.06 ? 290 TYR D CA 1 ATOM 4754 C C . TYR D 2 120 ? 9.717 2.318 -13.190 1.00 87.33 ? 290 TYR D C 1 ATOM 4755 O O . TYR D 2 120 ? 8.594 2.602 -13.621 1.00 87.85 ? 290 TYR D O 1 ATOM 4756 C CB . TYR D 2 120 ? 10.630 1.442 -15.372 1.00 88.88 ? 290 TYR D CB 1 ATOM 4757 C CG . TYR D 2 120 ? 11.536 1.741 -16.548 1.00 89.54 ? 290 TYR D CG 1 ATOM 4758 C CD1 . TYR D 2 120 ? 11.292 2.836 -17.379 1.00 89.93 ? 290 TYR D CD1 1 ATOM 4759 C CD2 . TYR D 2 120 ? 12.629 0.924 -16.838 1.00 89.89 ? 290 TYR D CD2 1 ATOM 4760 C CE1 . TYR D 2 120 ? 12.118 3.116 -18.468 1.00 90.00 ? 290 TYR D CE1 1 ATOM 4761 C CE2 . TYR D 2 120 ? 13.462 1.192 -17.925 1.00 89.99 ? 290 TYR D CE2 1 ATOM 4762 C CZ . TYR D 2 120 ? 13.200 2.291 -18.735 1.00 89.93 ? 290 TYR D CZ 1 ATOM 4763 O OH . TYR D 2 120 ? 14.017 2.565 -19.811 1.00 89.75 ? 290 TYR D OH 1 ATOM 4764 N N . SER D 2 121 ? 9.965 2.043 -11.910 1.00 86.73 ? 291 SER D N 1 ATOM 4765 C CA . SER D 2 121 ? 8.937 2.067 -10.877 1.00 86.22 ? 291 SER D CA 1 ATOM 4766 C C . SER D 2 121 ? 8.676 3.495 -10.409 1.00 85.66 ? 291 SER D C 1 ATOM 4767 O O . SER D 2 121 ? 9.576 4.339 -10.438 1.00 85.10 ? 291 SER D O 1 ATOM 4768 C CB . SER D 2 121 ? 9.359 1.191 -9.695 1.00 86.64 ? 291 SER D CB 1 ATOM 4769 O OG . SER D 2 121 ? 8.493 1.362 -8.585 1.00 87.16 ? 291 SER D OG 1 ATOM 4770 N N . SER D 2 122 ? 7.442 3.757 -9.976 1.00 84.94 ? 292 SER D N 1 ATOM 4771 C CA . SER D 2 122 ? 7.064 5.082 -9.480 1.00 84.02 ? 292 SER D CA 1 ATOM 4772 C C . SER D 2 122 ? 7.450 5.283 -8.010 1.00 83.08 ? 292 SER D C 1 ATOM 4773 O O . SER D 2 122 ? 7.362 6.396 -7.479 1.00 82.37 ? 292 SER D O 1 ATOM 4774 C CB . SER D 2 122 ? 5.569 5.338 -9.692 1.00 84.01 ? 292 SER D CB 1 ATOM 4775 O OG . SER D 2 122 ? 4.784 4.685 -8.710 1.00 85.27 ? 292 SER D OG 1 ATOM 4776 N N . LYS D 2 123 ? 7.882 4.199 -7.369 1.00 82.39 ? 293 LYS D N 1 ATOM 4777 C CA . LYS D 2 123 ? 8.312 4.227 -5.972 1.00 82.67 ? 293 LYS D CA 1 ATOM 4778 C C . LYS D 2 123 ? 9.800 4.559 -5.828 1.00 81.19 ? 293 LYS D C 1 ATOM 4779 O O . LYS D 2 123 ? 10.218 5.169 -4.836 1.00 80.53 ? 293 LYS D O 1 ATOM 4780 C CB . LYS D 2 123 ? 7.991 2.894 -5.282 1.00 83.40 ? 293 LYS D CB 1 ATOM 4781 C CG . LYS D 2 123 ? 6.525 2.732 -4.869 1.00 84.14 ? 293 LYS D CG 1 ATOM 4782 C CD . LYS D 2 123 ? 6.322 1.493 -3.992 1.00 84.07 ? 293 LYS D CD 1 ATOM 4783 C CE . LYS D 2 123 ? 5.066 1.605 -3.130 1.00 84.56 ? 293 LYS D CE 1 ATOM 4784 N NZ . LYS D 2 123 ? 5.157 2.695 -2.108 1.00 84.38 ? 293 LYS D NZ 1 ATOM 4785 N N . LYS D 2 124 ? 10.588 4.155 -6.824 1.00 79.60 ? 294 LYS D N 1 ATOM 4786 C CA . LYS D 2 124 ? 12.029 4.405 -6.840 1.00 77.75 ? 294 LYS D CA 1 ATOM 4787 C C . LYS D 2 124 ? 12.364 5.788 -7.399 1.00 75.46 ? 294 LYS D C 1 ATOM 4788 O O . LYS D 2 124 ? 11.643 6.315 -8.248 1.00 74.46 ? 294 LYS D O 1 ATOM 4789 C CB . LYS D 2 124 ? 12.749 3.321 -7.648 1.00 78.72 ? 294 LYS D CB 1 ATOM 4790 C CG . LYS D 2 124 ? 12.867 1.962 -6.953 1.00 79.57 ? 294 LYS D CG 1 ATOM 4791 C CD . LYS D 2 124 ? 13.972 1.952 -5.895 1.00 80.13 ? 294 LYS D CD 1 ATOM 4792 C CE . LYS D 2 124 ? 14.515 0.542 -5.654 1.00 80.65 ? 294 LYS D CE 1 ATOM 4793 N NZ . LYS D 2 124 ? 13.501 -0.408 -5.103 1.00 80.37 ? 294 LYS D NZ 1 ATOM 4794 N N . LEU D 2 125 ? 13.465 6.364 -6.917 1.00 73.27 ? 295 LEU D N 1 ATOM 4795 C CA . LEU D 2 125 ? 13.912 7.687 -7.358 1.00 71.30 ? 295 LEU D CA 1 ATOM 4796 C C . LEU D 2 125 ? 15.182 7.629 -8.214 1.00 69.47 ? 295 LEU D C 1 ATOM 4797 O O . LEU D 2 125 ? 16.231 7.147 -7.768 1.00 68.80 ? 295 LEU D O 1 ATOM 4798 C CB . LEU D 2 125 ? 14.110 8.633 -6.166 1.00 70.92 ? 295 LEU D CB 1 ATOM 4799 C CG . LEU D 2 125 ? 12.887 9.063 -5.346 1.00 70.93 ? 295 LEU D CG 1 ATOM 4800 C CD1 . LEU D 2 125 ? 13.321 9.944 -4.182 1.00 71.07 ? 295 LEU D CD1 1 ATOM 4801 C CD2 . LEU D 2 125 ? 11.843 9.779 -6.198 1.00 71.43 ? 295 LEU D CD2 1 ATOM 4802 N N . CYS D 2 126 ? 15.064 8.140 -9.440 1.00 67.05 ? 296 CYS D N 1 ATOM 4803 C CA . CYS D 2 126 ? 16.154 8.141 -10.413 1.00 64.04 ? 296 CYS D CA 1 ATOM 4804 C C . CYS D 2 126 ? 16.917 9.463 -10.438 1.00 61.86 ? 296 CYS D C 1 ATOM 4805 O O . CYS D 2 126 ? 16.334 10.525 -10.644 1.00 61.49 ? 296 CYS D O 1 ATOM 4806 C CB . CYS D 2 126 ? 15.623 7.796 -11.804 1.00 63.91 ? 296 CYS D CB 1 ATOM 4807 S SG . CYS D 2 126 ? 15.448 6.015 -12.098 1.00 65.12 ? 296 CYS D SG 1 ATOM 4808 N N . THR D 2 127 ? 18.225 9.380 -10.215 1.00 60.09 ? 297 THR D N 1 ATOM 4809 C CA . THR D 2 127 ? 19.108 10.547 -10.224 1.00 59.62 ? 297 THR D CA 1 ATOM 4810 C C . THR D 2 127 ? 19.401 11.041 -11.650 1.00 57.99 ? 297 THR D C 1 ATOM 4811 O O . THR D 2 127 ? 19.551 10.245 -12.580 1.00 57.03 ? 297 THR D O 1 ATOM 4812 C CB . THR D 2 127 ? 20.442 10.233 -9.509 1.00 60.42 ? 297 THR D CB 1 ATOM 4813 O OG1 . THR D 2 127 ? 20.174 9.585 -8.257 1.00 60.95 ? 297 THR D OG1 1 ATOM 4814 C CG2 . THR D 2 127 ? 21.242 11.506 -9.253 1.00 60.71 ? 297 THR D CG2 1 ATOM 4815 N N . LEU D 2 128 ? 19.474 12.359 -11.809 1.00 56.28 ? 298 LEU D N 1 ATOM 4816 C CA . LEU D 2 128 ? 19.859 12.967 -13.077 1.00 55.30 ? 298 LEU D CA 1 ATOM 4817 C C . LEU D 2 128 ? 21.364 13.260 -13.081 1.00 54.26 ? 298 LEU D C 1 ATOM 4818 O O . LEU D 2 128 ? 21.947 13.549 -12.031 1.00 52.57 ? 298 LEU D O 1 ATOM 4819 C CB . LEU D 2 128 ? 19.059 14.255 -13.326 1.00 55.69 ? 298 LEU D CB 1 ATOM 4820 C CG . LEU D 2 128 ? 17.527 14.189 -13.278 1.00 56.11 ? 298 LEU D CG 1 ATOM 4821 C CD1 . LEU D 2 128 ? 16.914 15.577 -13.265 1.00 55.61 ? 298 LEU D CD1 1 ATOM 4822 C CD2 . LEU D 2 128 ? 16.979 13.387 -14.443 1.00 56.47 ? 298 LEU D CD2 1 ATOM 4823 N N . ALA D 2 129 ? 21.980 13.185 -14.263 1.00 53.50 ? 299 ALA D N 1 ATOM 4824 C CA . ALA D 2 129 ? 23.427 13.379 -14.415 1.00 53.16 ? 299 ALA D CA 1 ATOM 4825 C C . ALA D 2 129 ? 23.824 14.850 -14.558 1.00 53.27 ? 299 ALA D C 1 ATOM 4826 O O . ALA D 2 129 ? 24.822 15.172 -15.204 1.00 52.39 ? 299 ALA D O 1 ATOM 4827 C CB . ALA D 2 129 ? 23.955 12.557 -15.590 1.00 52.97 ? 299 ALA D CB 1 ATOM 4828 N N . ILE D 2 130 ? 23.027 15.733 -13.958 1.00 54.55 ? 300 ILE D N 1 ATOM 4829 C CA . ILE D 2 130 ? 23.311 17.167 -13.924 1.00 56.20 ? 300 ILE D CA 1 ATOM 4830 C C . ILE D 2 130 ? 23.338 17.632 -12.473 1.00 57.79 ? 300 ILE D C 1 ATOM 4831 O O . ILE D 2 130 ? 22.402 17.380 -11.715 1.00 59.90 ? 300 ILE D O 1 ATOM 4832 C CB . ILE D 2 130 ? 22.271 17.996 -14.736 1.00 56.13 ? 300 ILE D CB 1 ATOM 4833 C CG1 . ILE D 2 130 ? 22.274 17.574 -16.209 1.00 56.12 ? 300 ILE D CG1 1 ATOM 4834 C CG2 . ILE D 2 130 ? 22.558 19.497 -14.600 1.00 56.10 ? 300 ILE D CG2 1 ATOM 4835 C CD1 . ILE D 2 130 ? 21.143 18.148 -17.044 1.00 56.88 ? 300 ILE D CD1 1 ATOM 4836 N N . HIS D 2 131 ? 24.420 18.298 -12.088 1.00 58.85 ? 301 HIS D N 1 ATOM 4837 C CA . HIS D 2 131 ? 24.599 18.751 -10.721 1.00 60.66 ? 301 HIS D CA 1 ATOM 4838 C C . HIS D 2 131 ? 24.896 20.243 -10.695 1.00 62.58 ? 301 HIS D C 1 ATOM 4839 O O . HIS D 2 131 ? 25.201 20.844 -11.729 1.00 62.82 ? 301 HIS D O 1 ATOM 4840 C CB . HIS D 2 131 ? 25.729 17.973 -10.040 1.00 61.82 ? 301 HIS D CB 1 ATOM 4841 C CG . HIS D 2 131 ? 25.413 16.526 -9.801 1.00 63.14 ? 301 HIS D CG 1 ATOM 4842 N ND1 . HIS D 2 131 ? 25.350 15.977 -8.537 1.00 63.60 ? 301 HIS D ND1 1 ATOM 4843 C CD2 . HIS D 2 131 ? 25.146 15.515 -10.663 1.00 63.18 ? 301 HIS D CD2 1 ATOM 4844 C CE1 . HIS D 2 131 ? 25.064 14.690 -8.632 1.00 63.86 ? 301 HIS D CE1 1 ATOM 4845 N NE2 . HIS D 2 131 ? 24.930 14.385 -9.911 1.00 64.04 ? 301 HIS D NE2 1 ATOM 4846 N N . ALA D 2 132 ? 24.790 20.843 -9.513 1.00 63.71 ? 302 ALA D N 1 ATOM 4847 C CA . ALA D 2 132 ? 25.101 22.253 -9.353 1.00 64.26 ? 302 ALA D CA 1 ATOM 4848 C C . ALA D 2 132 ? 26.521 22.431 -8.833 1.00 65.04 ? 302 ALA D C 1 ATOM 4849 O O . ALA D 2 132 ? 26.965 21.705 -7.944 1.00 64.27 ? 302 ALA D O 1 ATOM 4850 C CB . ALA D 2 132 ? 24.096 22.920 -8.435 1.00 64.67 ? 302 ALA D CB 1 ATOM 4851 N N . MET D 2 133 ? 27.238 23.380 -9.425 1.00 67.09 ? 303 MET D N 1 ATOM 4852 C CA . MET D 2 133 ? 28.571 23.739 -8.972 1.00 69.04 ? 303 MET D CA 1 ATOM 4853 C C . MET D 2 133 ? 28.863 25.206 -9.265 1.00 69.84 ? 303 MET D C 1 ATOM 4854 O O . MET D 2 133 ? 28.660 25.686 -10.385 1.00 70.84 ? 303 MET D O 1 ATOM 4855 C CB . MET D 2 133 ? 29.636 22.839 -9.603 1.00 69.42 ? 303 MET D CB 1 ATOM 4856 C CG . MET D 2 133 ? 30.927 22.791 -8.801 1.00 70.23 ? 303 MET D CG 1 ATOM 4857 S SD . MET D 2 133 ? 32.242 21.848 -9.593 1.00 70.54 ? 303 MET D SD 1 ATOM 4858 C CE . MET D 2 133 ? 33.525 21.926 -8.342 1.00 70.11 ? 303 MET D CE 1 ATOM 4859 N N . ASP D 2 134 ? 29.327 25.908 -8.236 1.00 70.20 ? 304 ASP D N 1 ATOM 4860 C CA . ASP D 2 134 ? 29.710 27.304 -8.347 1.00 69.58 ? 304 ASP D CA 1 ATOM 4861 C C . ASP D 2 134 ? 31.231 27.387 -8.417 1.00 69.51 ? 304 ASP D C 1 ATOM 4862 O O . ASP D 2 134 ? 31.926 27.163 -7.421 1.00 69.30 ? 304 ASP D O 1 ATOM 4863 C CB . ASP D 2 134 ? 29.170 28.106 -7.158 1.00 70.25 ? 304 ASP D CB 1 ATOM 4864 C CG . ASP D 2 134 ? 27.647 28.044 -7.041 1.00 70.54 ? 304 ASP D CG 1 ATOM 4865 O OD1 . ASP D 2 134 ? 26.941 28.390 -8.015 1.00 70.77 ? 304 ASP D OD1 1 ATOM 4866 O OD2 . ASP D 2 134 ? 27.157 27.662 -5.960 1.00 70.31 ? 304 ASP D OD2 1 ATOM 4867 N N . ILE D 2 135 ? 31.737 27.698 -9.607 1.00 69.13 ? 305 ILE D N 1 ATOM 4868 C CA . ILE D 2 135 ? 33.172 27.720 -9.866 1.00 68.69 ? 305 ILE D CA 1 ATOM 4869 C C . ILE D 2 135 ? 33.753 29.118 -9.620 1.00 69.99 ? 305 ILE D C 1 ATOM 4870 O O . ILE D 2 135 ? 33.289 30.101 -10.202 1.00 69.56 ? 305 ILE D O 1 ATOM 4871 C CB . ILE D 2 135 ? 33.500 27.201 -11.293 1.00 67.55 ? 305 ILE D CB 1 ATOM 4872 C CG1 . ILE D 2 135 ? 33.171 25.708 -11.397 1.00 66.59 ? 305 ILE D CG1 1 ATOM 4873 C CG2 . ILE D 2 135 ? 34.973 27.453 -11.651 1.00 67.35 ? 305 ILE D CG2 1 ATOM 4874 C CD1 . ILE D 2 135 ? 32.751 25.245 -12.771 1.00 65.71 ? 305 ILE D CD1 1 ATOM 4875 N N . PRO D 2 136 ? 34.764 29.206 -8.735 1.00 71.38 ? 306 PRO D N 1 ATOM 4876 C CA . PRO D 2 136 ? 35.419 30.482 -8.433 1.00 72.07 ? 306 PRO D CA 1 ATOM 4877 C C . PRO D 2 136 ? 36.231 31.028 -9.615 1.00 72.42 ? 306 PRO D C 1 ATOM 4878 O O . PRO D 2 136 ? 36.732 30.239 -10.427 1.00 72.92 ? 306 PRO D O 1 ATOM 4879 C CB . PRO D 2 136 ? 36.353 30.127 -7.269 1.00 72.19 ? 306 PRO D CB 1 ATOM 4880 C CG . PRO D 2 136 ? 36.619 28.661 -7.426 1.00 71.87 ? 306 PRO D CG 1 ATOM 4881 C CD . PRO D 2 136 ? 35.341 28.089 -7.958 1.00 71.42 ? 306 PRO D CD 1 ATOM 4882 N N . PRO D 2 137 ? 36.342 32.371 -9.725 1.00 72.11 ? 307 PRO D N 1 ATOM 4883 C CA . PRO D 2 137 ? 37.259 33.005 -10.676 1.00 70.97 ? 307 PRO D CA 1 ATOM 4884 C C . PRO D 2 137 ? 38.703 32.511 -10.513 1.00 69.67 ? 307 PRO D C 1 ATOM 4885 O O . PRO D 2 137 ? 39.052 31.994 -9.446 1.00 69.22 ? 307 PRO D O 1 ATOM 4886 C CB . PRO D 2 137 ? 37.140 34.495 -10.330 1.00 71.41 ? 307 PRO D CB 1 ATOM 4887 C CG . PRO D 2 137 ? 35.757 34.634 -9.805 1.00 71.63 ? 307 PRO D CG 1 ATOM 4888 C CD . PRO D 2 137 ? 35.558 33.381 -8.986 1.00 72.22 ? 307 PRO D CD 1 ATOM 4889 N N . PRO D 2 138 ? 39.542 32.667 -11.562 1.00 68.80 ? 308 PRO D N 1 ATOM 4890 C CA . PRO D 2 138 ? 39.256 33.349 -12.834 1.00 67.77 ? 308 PRO D CA 1 ATOM 4891 C C . PRO D 2 138 ? 38.317 32.580 -13.774 1.00 66.10 ? 308 PRO D C 1 ATOM 4892 O O . PRO D 2 138 ? 37.556 33.206 -14.521 1.00 65.62 ? 308 PRO D O 1 ATOM 4893 C CB . PRO D 2 138 ? 40.648 33.505 -13.475 1.00 68.38 ? 308 PRO D CB 1 ATOM 4894 C CG . PRO D 2 138 ? 41.647 33.117 -12.397 1.00 68.26 ? 308 PRO D CG 1 ATOM 4895 C CD . PRO D 2 138 ? 40.921 32.146 -11.537 1.00 68.70 ? 308 PRO D CD 1 ATOM 4896 N N . THR D 2 139 ? 38.365 31.247 -13.718 1.00 63.82 ? 309 THR D N 1 ATOM 4897 C CA . THR D 2 139 ? 37.607 30.383 -14.633 1.00 62.23 ? 309 THR D CA 1 ATOM 4898 C C . THR D 2 139 ? 36.093 30.631 -14.579 1.00 60.85 ? 309 THR D C 1 ATOM 4899 O O . THR D 2 139 ? 35.457 30.848 -15.612 1.00 60.65 ? 309 THR D O 1 ATOM 4900 C CB . THR D 2 139 ? 37.902 28.880 -14.389 1.00 62.19 ? 309 THR D CB 1 ATOM 4901 O OG1 . THR D 2 139 ? 39.319 28.658 -14.324 1.00 61.94 ? 309 THR D OG1 1 ATOM 4902 C CG2 . THR D 2 139 ? 37.311 28.033 -15.505 1.00 61.93 ? 309 THR D CG2 1 ATOM 4903 N N . GLY D 2 140 ? 35.527 30.596 -13.376 1.00 59.59 ? 310 GLY D N 1 ATOM 4904 C CA . GLY D 2 140 ? 34.103 30.836 -13.185 1.00 56.99 ? 310 GLY D CA 1 ATOM 4905 C C . GLY D 2 140 ? 33.780 32.274 -12.807 1.00 56.00 ? 310 GLY D C 1 ATOM 4906 O O . GLY D 2 140 ? 34.691 33.069 -12.572 1.00 56.10 ? 310 GLY D O 1 ATOM 4907 N N . PRO D 2 141 ? 32.478 32.620 -12.727 1.00 54.31 ? 311 PRO D N 1 ATOM 4908 C CA . PRO D 2 141 ? 31.331 31.718 -12.883 1.00 52.87 ? 311 PRO D CA 1 ATOM 4909 C C . PRO D 2 141 ? 31.249 31.096 -14.278 1.00 51.13 ? 311 PRO D C 1 ATOM 4910 O O . PRO D 2 141 ? 31.497 31.777 -15.282 1.00 50.63 ? 311 PRO D O 1 ATOM 4911 C CB . PRO D 2 141 ? 30.123 32.634 -12.634 1.00 53.58 ? 311 PRO D CB 1 ATOM 4912 C CG . PRO D 2 141 ? 30.626 34.014 -12.893 1.00 54.31 ? 311 PRO D CG 1 ATOM 4913 C CD . PRO D 2 141 ? 32.054 34.008 -12.471 1.00 54.14 ? 311 PRO D CD 1 ATOM 4914 N N . THR D 2 142 ? 30.915 29.807 -14.329 1.00 48.87 ? 312 THR D N 1 ATOM 4915 C CA . THR D 2 142 ? 30.759 29.093 -15.604 1.00 45.52 ? 312 THR D CA 1 ATOM 4916 C C . THR D 2 142 ? 29.994 27.787 -15.465 1.00 44.05 ? 312 THR D C 1 ATOM 4917 O O . THR D 2 142 ? 29.976 27.168 -14.390 1.00 42.64 ? 312 THR D O 1 ATOM 4918 C CB . THR D 2 142 ? 32.131 28.782 -16.272 1.00 45.07 ? 312 THR D CB 1 ATOM 4919 O OG1 . THR D 2 142 ? 31.916 28.104 -17.518 1.00 44.64 ? 312 THR D OG1 1 ATOM 4920 C CG2 . THR D 2 142 ? 33.007 27.922 -15.365 1.00 42.05 ? 312 THR D CG2 1 ATOM 4921 N N . TRP D 2 143 ? 29.365 27.377 -16.566 1.00 42.22 ? 313 TRP D N 1 ATOM 4922 C CA . TRP D 2 143 ? 28.915 26.002 -16.725 1.00 40.71 ? 313 TRP D CA 1 ATOM 4923 C C . TRP D 2 143 ? 30.137 25.149 -16.996 1.00 39.29 ? 313 TRP D C 1 ATOM 4924 O O . TRP D 2 143 ? 31.196 25.672 -17.346 1.00 40.05 ? 313 TRP D O 1 ATOM 4925 C CB . TRP D 2 143 ? 27.969 25.874 -17.908 1.00 42.40 ? 313 TRP D CB 1 ATOM 4926 C CG . TRP D 2 143 ? 26.647 26.533 -17.723 1.00 43.57 ? 313 TRP D CG 1 ATOM 4927 C CD1 . TRP D 2 143 ? 26.386 27.869 -17.784 1.00 43.40 ? 313 TRP D CD1 1 ATOM 4928 C CD2 . TRP D 2 143 ? 25.388 25.885 -17.468 1.00 43.40 ? 313 TRP D CD2 1 ATOM 4929 N NE1 . TRP D 2 143 ? 25.044 28.099 -17.579 1.00 43.81 ? 313 TRP D NE1 1 ATOM 4930 C CE2 . TRP D 2 143 ? 24.407 26.900 -17.383 1.00 43.41 ? 313 TRP D CE2 1 ATOM 4931 C CE3 . TRP D 2 143 ? 24.995 24.548 -17.309 1.00 42.79 ? 313 TRP D CE3 1 ATOM 4932 C CZ2 . TRP D 2 143 ? 23.056 26.625 -17.143 1.00 42.97 ? 313 TRP D CZ2 1 ATOM 4933 C CZ3 . TRP D 2 143 ? 23.645 24.271 -17.063 1.00 43.57 ? 313 TRP D CZ3 1 ATOM 4934 C CH2 . TRP D 2 143 ? 22.693 25.309 -16.983 1.00 43.43 ? 313 TRP D CH2 1 ATOM 4935 N N . ALA D 2 144 ? 29.993 23.837 -16.840 1.00 37.31 ? 314 ALA D N 1 ATOM 4936 C CA . ALA D 2 144 ? 31.050 22.904 -17.204 1.00 35.23 ? 314 ALA D CA 1 ATOM 4937 C C . ALA D 2 144 ? 30.424 21.690 -17.852 1.00 33.92 ? 314 ALA D C 1 ATOM 4938 O O . ALA D 2 144 ? 29.462 21.147 -17.338 1.00 32.05 ? 314 ALA D O 1 ATOM 4939 C CB . ALA D 2 144 ? 31.870 22.498 -15.988 1.00 34.67 ? 314 ALA D CB 1 ATOM 4940 N N . LEU D 2 145 ? 30.977 21.274 -18.989 1.00 33.82 ? 315 LEU D N 1 ATOM 4941 C CA . LEU D 2 145 ? 30.439 20.144 -19.732 1.00 32.67 ? 315 LEU D CA 1 ATOM 4942 C C . LEU D 2 145 ? 31.360 18.946 -19.557 1.00 32.30 ? 315 LEU D C 1 ATOM 4943 O O . LEU D 2 145 ? 32.435 18.866 -20.153 1.00 33.29 ? 315 LEU D O 1 ATOM 4944 C CB . LEU D 2 145 ? 30.228 20.512 -21.207 1.00 32.17 ? 315 LEU D CB 1 ATOM 4945 C CG . LEU D 2 145 ? 29.415 21.787 -21.486 1.00 31.54 ? 315 LEU D CG 1 ATOM 4946 C CD1 . LEU D 2 145 ? 29.523 22.211 -22.953 1.00 30.67 ? 315 LEU D CD1 1 ATOM 4947 C CD2 . LEU D 2 145 ? 27.954 21.615 -21.087 1.00 31.24 ? 315 LEU D CD2 1 ATOM 4948 N N . GLY D 2 146 ? 30.942 18.035 -18.694 1.00 31.59 ? 316 GLY D N 1 ATOM 4949 C CA . GLY D 2 146 ? 31.739 16.863 -18.372 1.00 31.91 ? 316 GLY D CA 1 ATOM 4950 C C . GLY D 2 146 ? 31.202 15.645 -19.077 1.00 30.22 ? 316 GLY D C 1 ATOM 4951 O O . GLY D 2 146 ? 30.558 15.767 -20.121 1.00 30.93 ? 316 GLY D O 1 ATOM 4952 N N . ALA D 2 147 ? 31.440 14.474 -18.491 1.00 29.97 ? 317 ALA D N 1 ATOM 4953 C CA . ALA D 2 147 ? 31.166 13.192 -19.164 1.00 28.63 ? 317 ALA D CA 1 ATOM 4954 C C . ALA D 2 147 ? 29.724 12.992 -19.612 1.00 29.12 ? 317 ALA D C 1 ATOM 4955 O O . ALA D 2 147 ? 29.474 12.251 -20.556 1.00 30.62 ? 317 ALA D O 1 ATOM 4956 C CB . ALA D 2 147 ? 31.621 12.042 -18.314 1.00 28.21 ? 317 ALA D CB 1 ATOM 4957 N N . THR D 2 148 ? 28.774 13.640 -18.942 1.00 29.37 ? 318 THR D N 1 ATOM 4958 C CA . THR D 2 148 ? 27.378 13.603 -19.391 1.00 29.73 ? 318 THR D CA 1 ATOM 4959 C C . THR D 2 148 ? 27.250 14.169 -20.815 1.00 29.55 ? 318 THR D C 1 ATOM 4960 O O . THR D 2 148 ? 26.524 13.618 -21.642 1.00 28.49 ? 318 THR D O 1 ATOM 4961 C CB . THR D 2 148 ? 26.445 14.359 -18.412 1.00 29.44 ? 318 THR D CB 1 ATOM 4962 O OG1 . THR D 2 148 ? 26.461 13.696 -17.143 1.00 31.03 ? 318 THR D OG1 1 ATOM 4963 C CG2 . THR D 2 148 ? 25.013 14.416 -18.925 1.00 26.90 ? 318 THR D CG2 1 ATOM 4964 N N . PHE D 2 149 ? 27.973 15.253 -21.087 1.00 29.24 ? 319 PHE D N 1 ATOM 4965 C CA . PHE D 2 149 ? 27.941 15.902 -22.391 1.00 30.18 ? 319 PHE D CA 1 ATOM 4966 C C . PHE D 2 149 ? 28.830 15.171 -23.412 1.00 29.90 ? 319 PHE D C 1 ATOM 4967 O O . PHE D 2 149 ? 28.405 14.908 -24.530 1.00 31.64 ? 319 PHE D O 1 ATOM 4968 C CB . PHE D 2 149 ? 28.377 17.362 -22.251 1.00 31.53 ? 319 PHE D CB 1 ATOM 4969 C CG . PHE D 2 149 ? 28.113 18.184 -23.462 1.00 33.28 ? 319 PHE D CG 1 ATOM 4970 C CD1 . PHE D 2 149 ? 29.106 18.383 -24.416 1.00 33.45 ? 319 PHE D CD1 1 ATOM 4971 C CD2 . PHE D 2 149 ? 26.858 18.765 -23.663 1.00 33.60 ? 319 PHE D CD2 1 ATOM 4972 C CE1 . PHE D 2 149 ? 28.851 19.161 -25.549 1.00 33.34 ? 319 PHE D CE1 1 ATOM 4973 C CE2 . PHE D 2 149 ? 26.597 19.542 -24.798 1.00 32.22 ? 319 PHE D CE2 1 ATOM 4974 C CZ . PHE D 2 149 ? 27.585 19.732 -25.737 1.00 32.72 ? 319 PHE D CZ 1 ATOM 4975 N N . ILE D 2 150 ? 30.056 14.846 -23.011 1.00 27.99 ? 320 ILE D N 1 ATOM 4976 C CA . ILE D 2 150 ? 31.021 14.163 -23.869 1.00 28.26 ? 320 ILE D CA 1 ATOM 4977 C C . ILE D 2 150 ? 30.533 12.770 -24.340 1.00 28.63 ? 320 ILE D C 1 ATOM 4978 O O . ILE D 2 150 ? 30.777 12.388 -25.483 1.00 27.01 ? 320 ILE D O 1 ATOM 4979 C CB . ILE D 2 150 ? 32.433 14.137 -23.204 1.00 27.45 ? 320 ILE D CB 1 ATOM 4980 C CG1 . ILE D 2 150 ? 32.934 15.580 -23.049 1.00 27.91 ? 320 ILE D CG1 1 ATOM 4981 C CG2 . ILE D 2 150 ? 33.427 13.309 -24.019 1.00 25.83 ? 320 ILE D CG2 1 ATOM 4982 C CD1 . ILE D 2 150 ? 33.950 15.797 -21.961 1.00 28.11 ? 320 ILE D CD1 1 ATOM 4983 N N . ARG D 2 151 ? 29.837 12.037 -23.465 1.00 29.41 ? 321 ARG D N 1 ATOM 4984 C CA . ARG D 2 151 ? 29.164 10.781 -23.833 1.00 29.66 ? 321 ARG D CA 1 ATOM 4985 C C . ARG D 2 151 ? 28.237 10.965 -25.030 1.00 29.35 ? 321 ARG D C 1 ATOM 4986 O O . ARG D 2 151 ? 28.182 10.115 -25.909 1.00 30.44 ? 321 ARG D O 1 ATOM 4987 C CB . ARG D 2 151 ? 28.323 10.251 -22.679 1.00 29.22 ? 321 ARG D CB 1 ATOM 4988 C CG . ARG D 2 151 ? 28.971 9.216 -21.831 1.00 29.84 ? 321 ARG D CG 1 ATOM 4989 C CD . ARG D 2 151 ? 27.907 8.506 -20.978 1.00 28.63 ? 321 ARG D CD 1 ATOM 4990 N NE . ARG D 2 151 ? 27.229 9.412 -20.048 1.00 27.51 ? 321 ARG D NE 1 ATOM 4991 C CZ . ARG D 2 151 ? 27.739 9.794 -18.876 1.00 28.95 ? 321 ARG D CZ 1 ATOM 4992 N NH1 . ARG D 2 151 ? 28.941 9.358 -18.500 1.00 26.65 ? 321 ARG D NH1 1 ATOM 4993 N NH2 . ARG D 2 151 ? 27.050 10.608 -18.074 1.00 28.36 ? 321 ARG D NH2 1 ATOM 4994 N N . LYS D 2 152 ? 27.497 12.067 -25.057 1.00 29.16 ? 322 LYS D N 1 ATOM 4995 C CA . LYS D 2 152 ? 26.681 12.357 -26.226 1.00 30.20 ? 322 LYS D CA 1 ATOM 4996 C C . LYS D 2 152 ? 27.499 12.891 -27.407 1.00 28.25 ? 322 LYS D C 1 ATOM 4997 O O . LYS D 2 152 ? 27.285 12.480 -28.544 1.00 28.87 ? 322 LYS D O 1 ATOM 4998 C CB . LYS D 2 152 ? 25.535 13.314 -25.904 1.00 30.88 ? 322 LYS D CB 1 ATOM 4999 C CG . LYS D 2 152 ? 24.215 12.778 -26.459 1.00 32.52 ? 322 LYS D CG 1 ATOM 5000 C CD . LYS D 2 152 ? 23.584 13.734 -27.411 1.00 33.05 ? 322 LYS D CD 1 ATOM 5001 C CE . LYS D 2 152 ? 22.736 13.004 -28.421 1.00 32.39 ? 322 LYS D CE 1 ATOM 5002 N NZ . LYS D 2 152 ? 21.418 12.673 -27.855 1.00 35.41 ? 322 LYS D NZ 1 ATOM 5003 N N . PHE D 2 153 ? 28.423 13.808 -27.129 1.00 26.25 ? 323 PHE D N 1 ATOM 5004 C CA . PHE D 2 153 ? 29.217 14.449 -28.183 1.00 25.57 ? 323 PHE D CA 1 ATOM 5005 C C . PHE D 2 153 ? 30.721 14.201 -28.089 1.00 25.07 ? 323 PHE D C 1 ATOM 5006 O O . PHE D 2 153 ? 31.422 14.788 -27.253 1.00 25.04 ? 323 PHE D O 1 ATOM 5007 C CB . PHE D 2 153 ? 28.861 15.931 -28.292 1.00 25.39 ? 323 PHE D CB 1 ATOM 5008 C CG . PHE D 2 153 ? 27.418 16.158 -28.623 1.00 26.02 ? 323 PHE D CG 1 ATOM 5009 C CD1 . PHE D 2 153 ? 26.934 15.874 -29.900 1.00 27.11 ? 323 PHE D CD1 1 ATOM 5010 C CD2 . PHE D 2 153 ? 26.526 16.600 -27.651 1.00 26.81 ? 323 PHE D CD2 1 ATOM 5011 C CE1 . PHE D 2 153 ? 25.573 16.054 -30.210 1.00 27.89 ? 323 PHE D CE1 1 ATOM 5012 C CE2 . PHE D 2 153 ? 25.169 16.787 -27.949 1.00 27.43 ? 323 PHE D CE2 1 ATOM 5013 C CZ . PHE D 2 153 ? 24.691 16.508 -29.232 1.00 25.71 ? 323 PHE D CZ 1 ATOM 5014 N N . TYR D 2 154 ? 31.180 13.261 -28.912 1.00 25.43 ? 324 TYR D N 1 ATOM 5015 C CA . TYR D 2 154 ? 32.595 13.064 -29.222 1.00 25.99 ? 324 TYR D CA 1 ATOM 5016 C C . TYR D 2 154 ? 33.279 14.412 -29.384 1.00 27.11 ? 324 TYR D C 1 ATOM 5017 O O . TYR D 2 154 ? 32.791 15.284 -30.121 1.00 29.52 ? 324 TYR D O 1 ATOM 5018 C CB . TYR D 2 154 ? 32.732 12.280 -30.525 1.00 24.21 ? 324 TYR D CB 1 ATOM 5019 C CG . TYR D 2 154 ? 34.139 11.803 -30.788 1.00 24.33 ? 324 TYR D CG 1 ATOM 5020 C CD1 . TYR D 2 154 ? 35.104 12.662 -31.323 1.00 24.32 ? 324 TYR D CD1 1 ATOM 5021 C CD2 . TYR D 2 154 ? 34.512 10.499 -30.490 1.00 22.60 ? 324 TYR D CD2 1 ATOM 5022 C CE1 . TYR D 2 154 ? 36.395 12.229 -31.557 1.00 23.49 ? 324 TYR D CE1 1 ATOM 5023 C CE2 . TYR D 2 154 ? 35.803 10.053 -30.738 1.00 23.66 ? 324 TYR D CE2 1 ATOM 5024 C CZ . TYR D 2 154 ? 36.733 10.921 -31.266 1.00 23.26 ? 324 TYR D CZ 1 ATOM 5025 O OH . TYR D 2 154 ? 38.006 10.481 -31.490 1.00 23.55 ? 324 TYR D OH 1 ATOM 5026 N N . THR D 2 155 ? 34.405 14.586 -28.702 1.00 25.78 ? 325 THR D N 1 ATOM 5027 C CA . THR D 2 155 ? 34.975 15.928 -28.528 1.00 24.27 ? 325 THR D CA 1 ATOM 5028 C C . THR D 2 155 ? 36.419 15.971 -29.000 1.00 23.62 ? 325 THR D C 1 ATOM 5029 O O . THR D 2 155 ? 37.213 15.121 -28.634 1.00 23.16 ? 325 THR D O 1 ATOM 5030 C CB . THR D 2 155 ? 34.821 16.407 -27.047 1.00 23.84 ? 325 THR D CB 1 ATOM 5031 O OG1 . THR D 2 155 ? 33.433 16.404 -26.689 1.00 23.65 ? 325 THR D OG1 1 ATOM 5032 C CG2 . THR D 2 155 ? 35.383 17.791 -26.832 1.00 20.93 ? 325 THR D CG2 1 ATOM 5033 N N . GLU D 2 156 ? 36.727 16.951 -29.847 1.00 25.88 ? 326 GLU D N 1 ATOM 5034 C CA . GLU D 2 156 ? 38.072 17.182 -30.361 1.00 27.06 ? 326 GLU D CA 1 ATOM 5035 C C . GLU D 2 156 ? 38.579 18.496 -29.792 1.00 27.65 ? 326 GLU D C 1 ATOM 5036 O O . GLU D 2 156 ? 37.916 19.526 -29.932 1.00 28.37 ? 326 GLU D O 1 ATOM 5037 C CB . GLU D 2 156 ? 38.075 17.246 -31.891 1.00 28.31 ? 326 GLU D CB 1 ATOM 5038 C CG . GLU D 2 156 ? 39.413 17.685 -32.498 1.00 30.29 ? 326 GLU D CG 1 ATOM 5039 C CD . GLU D 2 156 ? 39.422 17.669 -34.025 1.00 30.74 ? 326 GLU D CD 1 ATOM 5040 O OE1 . GLU D 2 156 ? 39.415 18.754 -34.638 1.00 32.79 ? 326 GLU D OE1 1 ATOM 5041 O OE2 . GLU D 2 156 ? 39.445 16.572 -34.621 1.00 32.93 ? 326 GLU D OE2 1 ATOM 5042 N N . PHE D 2 157 ? 39.748 18.447 -29.147 1.00 25.67 ? 327 PHE D N 1 ATOM 5043 C CA . PHE D 2 157 ? 40.388 19.625 -28.587 1.00 26.80 ? 327 PHE D CA 1 ATOM 5044 C C . PHE D 2 157 ? 41.523 20.036 -29.503 1.00 27.51 ? 327 PHE D C 1 ATOM 5045 O O . PHE D 2 157 ? 42.466 19.285 -29.708 1.00 28.70 ? 327 PHE D O 1 ATOM 5046 C CB . PHE D 2 157 ? 40.912 19.338 -27.177 1.00 26.12 ? 327 PHE D CB 1 ATOM 5047 C CG . PHE D 2 157 ? 39.825 19.039 -26.172 1.00 25.05 ? 327 PHE D CG 1 ATOM 5048 C CD1 . PHE D 2 157 ? 39.245 20.062 -25.437 1.00 24.98 ? 327 PHE D CD1 1 ATOM 5049 C CD2 . PHE D 2 157 ? 39.383 17.735 -25.968 1.00 23.78 ? 327 PHE D CD2 1 ATOM 5050 C CE1 . PHE D 2 157 ? 38.248 19.791 -24.512 1.00 25.02 ? 327 PHE D CE1 1 ATOM 5051 C CE2 . PHE D 2 157 ? 38.396 17.462 -25.050 1.00 23.79 ? 327 PHE D CE2 1 ATOM 5052 C CZ . PHE D 2 157 ? 37.821 18.492 -24.324 1.00 24.67 ? 327 PHE D CZ 1 ATOM 5053 N N . ASP D 2 158 ? 41.417 21.239 -30.049 1.00 29.07 ? 328 ASP D N 1 ATOM 5054 C CA . ASP D 2 158 ? 42.285 21.693 -31.124 1.00 30.18 ? 328 ASP D CA 1 ATOM 5055 C C . ASP D 2 158 ? 43.209 22.803 -30.624 1.00 31.28 ? 328 ASP D C 1 ATOM 5056 O O . ASP D 2 158 ? 42.778 23.950 -30.456 1.00 32.47 ? 328 ASP D O 1 ATOM 5057 C CB . ASP D 2 158 ? 41.399 22.173 -32.283 1.00 30.25 ? 328 ASP D CB 1 ATOM 5058 C CG . ASP D 2 158 ? 42.173 22.486 -33.559 1.00 30.29 ? 328 ASP D CG 1 ATOM 5059 O OD1 . ASP D 2 158 ? 43.411 22.662 -33.516 1.00 31.00 ? 328 ASP D OD1 1 ATOM 5060 O OD2 . ASP D 2 158 ? 41.516 22.573 -34.622 1.00 28.54 ? 328 ASP D OD2 1 ATOM 5061 N N . ARG D 2 159 ? 44.471 22.449 -30.377 1.00 31.57 ? 329 ARG D N 1 ATOM 5062 C CA . ARG D 2 159 ? 45.485 23.401 -29.907 1.00 32.09 ? 329 ARG D CA 1 ATOM 5063 C C . ARG D 2 159 ? 45.978 24.303 -31.035 1.00 30.95 ? 329 ARG D C 1 ATOM 5064 O O . ARG D 2 159 ? 46.291 25.460 -30.806 1.00 28.83 ? 329 ARG D O 1 ATOM 5065 C CB . ARG D 2 159 ? 46.696 22.672 -29.314 1.00 34.73 ? 329 ARG D CB 1 ATOM 5066 C CG . ARG D 2 159 ? 46.455 21.930 -28.011 1.00 38.87 ? 329 ARG D CG 1 ATOM 5067 C CD . ARG D 2 159 ? 46.174 22.898 -26.861 1.00 42.77 ? 329 ARG D CD 1 ATOM 5068 N NE . ARG D 2 159 ? 47.201 23.932 -26.737 1.00 46.88 ? 329 ARG D NE 1 ATOM 5069 C CZ . ARG D 2 159 ? 48.317 23.816 -26.017 1.00 48.49 ? 329 ARG D CZ 1 ATOM 5070 N NH1 . ARG D 2 159 ? 48.577 22.705 -25.328 1.00 48.43 ? 329 ARG D NH1 1 ATOM 5071 N NH2 . ARG D 2 159 ? 49.174 24.826 -25.989 1.00 49.29 ? 329 ARG D NH2 1 ATOM 5072 N N . ARG D 2 160 ? 46.066 23.752 -32.244 1.00 31.35 ? 330 ARG D N 1 ATOM 5073 C CA . ARG D 2 160 ? 46.510 24.509 -33.419 1.00 32.36 ? 330 ARG D CA 1 ATOM 5074 C C . ARG D 2 160 ? 45.631 25.731 -33.680 1.00 30.33 ? 330 ARG D C 1 ATOM 5075 O O . ARG D 2 160 ? 46.146 26.810 -33.933 1.00 30.79 ? 330 ARG D O 1 ATOM 5076 C CB . ARG D 2 160 ? 46.587 23.599 -34.656 1.00 34.42 ? 330 ARG D CB 1 ATOM 5077 C CG . ARG D 2 160 ? 46.892 24.296 -35.968 1.00 37.86 ? 330 ARG D CG 1 ATOM 5078 C CD . ARG D 2 160 ? 48.194 25.103 -35.931 1.00 40.83 ? 330 ARG D CD 1 ATOM 5079 N NE . ARG D 2 160 ? 48.006 26.377 -36.626 1.00 43.72 ? 330 ARG D NE 1 ATOM 5080 C CZ . ARG D 2 160 ? 48.393 26.603 -37.871 1.00 44.86 ? 330 ARG D CZ 1 ATOM 5081 N NH1 . ARG D 2 160 ? 49.009 25.646 -38.557 1.00 47.94 ? 330 ARG D NH1 1 ATOM 5082 N NH2 . ARG D 2 160 ? 48.174 27.784 -38.426 1.00 44.73 ? 330 ARG D NH2 1 ATOM 5083 N N . ASN D 2 161 ? 44.319 25.563 -33.552 1.00 28.61 ? 331 ASN D N 1 ATOM 5084 C CA . ASN D 2 161 ? 43.355 26.609 -33.892 1.00 29.33 ? 331 ASN D CA 1 ATOM 5085 C C . ASN D 2 161 ? 42.617 27.226 -32.676 1.00 28.63 ? 331 ASN D C 1 ATOM 5086 O O . ASN D 2 161 ? 41.753 28.099 -32.856 1.00 24.93 ? 331 ASN D O 1 ATOM 5087 C CB . ASN D 2 161 ? 42.320 26.064 -34.898 1.00 28.95 ? 331 ASN D CB 1 ATOM 5088 C CG . ASN D 2 161 ? 42.947 25.581 -36.197 1.00 31.05 ? 331 ASN D CG 1 ATOM 5089 O OD1 . ASN D 2 161 ? 42.770 24.438 -36.592 1.00 31.95 ? 331 ASN D OD1 1 ATOM 5090 N ND2 . ASN D 2 161 ? 43.675 26.455 -36.869 1.00 33.17 ? 331 ASN D ND2 1 ATOM 5091 N N . ASN D 2 162 ? 42.965 26.775 -31.464 1.00 28.14 ? 332 ASN D N 1 ATOM 5092 C CA . ASN D 2 162 ? 42.265 27.159 -30.218 1.00 28.55 ? 332 ASN D CA 1 ATOM 5093 C C . ASN D 2 162 ? 40.740 27.109 -30.367 1.00 27.54 ? 332 ASN D C 1 ATOM 5094 O O . ASN D 2 162 ? 40.042 28.113 -30.226 1.00 28.82 ? 332 ASN D O 1 ATOM 5095 C CB . ASN D 2 162 ? 42.714 28.533 -29.692 1.00 29.87 ? 332 ASN D CB 1 ATOM 5096 C CG . ASN D 2 162 ? 44.194 28.571 -29.299 1.00 32.11 ? 332 ASN D CG 1 ATOM 5097 O OD1 . ASN D 2 162 ? 44.619 27.953 -28.320 1.00 30.00 ? 332 ASN D OD1 1 ATOM 5098 N ND2 . ASN D 2 162 ? 44.979 29.322 -30.066 1.00 33.21 ? 332 ASN D ND2 1 ATOM 5099 N N . ARG D 2 163 ? 40.234 25.931 -30.681 1.00 26.23 ? 333 ARG D N 1 ATOM 5100 C CA . ARG D 2 163 ? 38.800 25.714 -30.768 1.00 25.22 ? 333 ARG D CA 1 ATOM 5101 C C . ARG D 2 163 ? 38.498 24.314 -30.249 1.00 24.18 ? 333 ARG D C 1 ATOM 5102 O O . ARG D 2 163 ? 39.411 23.505 -30.071 1.00 25.35 ? 333 ARG D O 1 ATOM 5103 C CB . ARG D 2 163 ? 38.320 25.908 -32.218 1.00 24.88 ? 333 ARG D CB 1 ATOM 5104 C CG . ARG D 2 163 ? 39.095 25.063 -33.243 1.00 24.68 ? 333 ARG D CG 1 ATOM 5105 C CD . ARG D 2 163 ? 38.677 25.330 -34.666 1.00 23.19 ? 333 ARG D CD 1 ATOM 5106 N NE . ARG D 2 163 ? 39.089 24.221 -35.510 1.00 22.88 ? 333 ARG D NE 1 ATOM 5107 C CZ . ARG D 2 163 ? 38.738 24.042 -36.777 1.00 22.63 ? 333 ARG D CZ 1 ATOM 5108 N NH1 . ARG D 2 163 ? 37.947 24.909 -37.389 1.00 22.80 ? 333 ARG D NH1 1 ATOM 5109 N NH2 . ARG D 2 163 ? 39.183 22.974 -37.429 1.00 23.01 ? 333 ARG D NH2 1 ATOM 5110 N N . ILE D 2 164 ? 37.226 24.041 -29.986 1.00 24.81 ? 334 ILE D N 1 ATOM 5111 C CA . ILE D 2 164 ? 36.762 22.699 -29.625 1.00 24.02 ? 334 ILE D CA 1 ATOM 5112 C C . ILE D 2 164 ? 35.724 22.278 -30.658 1.00 25.04 ? 334 ILE D C 1 ATOM 5113 O O . ILE D 2 164 ? 34.871 23.082 -31.046 1.00 27.43 ? 334 ILE D O 1 ATOM 5114 C CB . ILE D 2 164 ? 36.146 22.653 -28.183 1.00 22.94 ? 334 ILE D CB 1 ATOM 5115 C CG1 . ILE D 2 164 ? 37.145 23.191 -27.152 1.00 23.07 ? 334 ILE D CG1 1 ATOM 5116 C CG2 . ILE D 2 164 ? 35.711 21.238 -27.804 1.00 19.91 ? 334 ILE D CG2 1 ATOM 5117 C CD1 . ILE D 2 164 ? 36.572 23.432 -25.754 1.00 23.87 ? 334 ILE D CD1 1 ATOM 5118 N N . GLY D 2 165 ? 35.810 21.029 -31.108 1.00 23.74 ? 335 GLY D N 1 ATOM 5119 C CA . GLY D 2 165 ? 34.873 20.473 -32.060 1.00 23.49 ? 335 GLY D CA 1 ATOM 5120 C C . GLY D 2 165 ? 34.039 19.372 -31.451 1.00 26.52 ? 335 GLY D C 1 ATOM 5121 O O . GLY D 2 165 ? 34.522 18.596 -30.613 1.00 26.62 ? 335 GLY D O 1 ATOM 5122 N N . PHE D 2 166 ? 32.777 19.316 -31.875 1.00 26.46 ? 336 PHE D N 1 ATOM 5123 C CA . PHE D 2 166 ? 31.835 18.293 -31.433 1.00 26.19 ? 336 PHE D CA 1 ATOM 5124 C C . PHE D 2 166 ? 31.222 17.528 -32.585 1.00 25.89 ? 336 PHE D C 1 ATOM 5125 O O . PHE D 2 166 ? 30.946 18.087 -33.647 1.00 26.23 ? 336 PHE D O 1 ATOM 5126 C CB . PHE D 2 166 ? 30.700 18.923 -30.632 1.00 25.91 ? 336 PHE D CB 1 ATOM 5127 C CG . PHE D 2 166 ? 31.139 19.533 -29.338 1.00 27.58 ? 336 PHE D CG 1 ATOM 5128 C CD1 . PHE D 2 166 ? 31.662 18.732 -28.309 1.00 26.97 ? 336 PHE D CD1 1 ATOM 5129 C CD2 . PHE D 2 166 ? 31.003 20.892 -29.123 1.00 26.13 ? 336 PHE D CD2 1 ATOM 5130 C CE1 . PHE D 2 166 ? 32.067 19.288 -27.107 1.00 25.69 ? 336 PHE D CE1 1 ATOM 5131 C CE2 . PHE D 2 166 ? 31.398 21.460 -27.907 1.00 26.94 ? 336 PHE D CE2 1 ATOM 5132 C CZ . PHE D 2 166 ? 31.930 20.645 -26.896 1.00 26.28 ? 336 PHE D CZ 1 ATOM 5133 N N . ALA D 2 167 ? 30.996 16.244 -32.351 1.00 25.58 ? 337 ALA D N 1 ATOM 5134 C CA . ALA D 2 167 ? 30.247 15.398 -33.254 1.00 26.38 ? 337 ALA D CA 1 ATOM 5135 C C . ALA D 2 167 ? 29.505 14.376 -32.409 1.00 28.39 ? 337 ALA D C 1 ATOM 5136 O O . ALA D 2 167 ? 29.943 14.034 -31.312 1.00 30.02 ? 337 ALA D O 1 ATOM 5137 C CB . ALA D 2 167 ? 31.175 14.705 -34.235 1.00 23.87 ? 337 ALA D CB 1 ATOM 5138 N N . LEU D 2 168 ? 28.381 13.900 -32.929 1.00 27.91 ? 338 LEU D N 1 ATOM 5139 C CA . LEU D 2 168 ? 27.576 12.894 -32.275 1.00 27.84 ? 338 LEU D CA 1 ATOM 5140 C C . LEU D 2 168 ? 28.404 11.619 -32.141 1.00 29.87 ? 338 LEU D C 1 ATOM 5141 O O . LEU D 2 168 ? 28.882 11.084 -33.150 1.00 28.39 ? 338 LEU D O 1 ATOM 5142 C CB . LEU D 2 168 ? 26.358 12.597 -33.141 1.00 28.44 ? 338 LEU D CB 1 ATOM 5143 C CG . LEU D 2 168 ? 24.946 12.416 -32.587 1.00 31.16 ? 338 LEU D CG 1 ATOM 5144 C CD1 . LEU D 2 168 ? 24.170 11.512 -33.566 1.00 31.59 ? 338 LEU D CD1 1 ATOM 5145 C CD2 . LEU D 2 168 ? 24.889 11.873 -31.153 1.00 29.12 ? 338 LEU D CD2 1 ATOM 5146 N N . ALA D 2 169 ? 28.574 11.139 -30.903 1.00 30.50 ? 339 ALA D N 1 ATOM 5147 C CA . ALA D 2 169 ? 29.282 9.882 -30.656 1.00 31.38 ? 339 ALA D CA 1 ATOM 5148 C C . ALA D 2 169 ? 28.489 8.697 -31.192 1.00 34.42 ? 339 ALA D C 1 ATOM 5149 O O . ALA D 2 169 ? 27.258 8.713 -31.169 1.00 33.75 ? 339 ALA D O 1 ATOM 5150 C CB . ALA D 2 169 ? 29.570 9.705 -29.189 1.00 27.06 ? 339 ALA D CB 1 ATOM 5151 N N . ARG D 2 170 ? 29.210 7.706 -31.713 1.00 38.10 ? 340 ARG D N 1 ATOM 5152 C CA . ARG D 2 170 ? 28.656 6.402 -32.067 1.00 42.98 ? 340 ARG D CA 1 ATOM 5153 C C . ARG D 2 170 ? 28.823 5.500 -30.860 1.00 46.00 ? 340 ARG D C 1 ATOM 5154 O O . ARG D 2 170 ? 29.906 5.466 -30.256 1.00 46.50 ? 340 ARG D O 1 ATOM 5155 C CB . ARG D 2 170 ? 29.463 5.755 -33.192 1.00 44.89 ? 340 ARG D CB 1 ATOM 5156 C CG . ARG D 2 170 ? 29.070 6.064 -34.605 1.00 47.46 ? 340 ARG D CG 1 ATOM 5157 C CD . ARG D 2 170 ? 29.471 4.882 -35.492 1.00 50.46 ? 340 ARG D CD 1 ATOM 5158 N NE . ARG D 2 170 ? 30.150 5.280 -36.727 1.00 53.78 ? 340 ARG D NE 1 ATOM 5159 C CZ . ARG D 2 170 ? 29.555 5.845 -37.780 1.00 56.15 ? 340 ARG D CZ 1 ATOM 5160 N NH1 . ARG D 2 170 ? 28.251 6.113 -37.767 1.00 55.93 ? 340 ARG D NH1 1 ATOM 5161 N NH2 . ARG D 2 170 ? 30.274 6.158 -38.855 1.00 57.49 ? 340 ARG D NH2 1 ATOM 5162 N N . HIS D 2 171 ? 27.778 4.753 -30.517 1.00 48.70 ? 341 HIS D N 1 ATOM 5163 C CA . HIS D 2 171 ? 27.858 3.798 -29.418 1.00 50.87 ? 341 HIS D CA 1 ATOM 5164 C C . HIS D 2 171 ? 27.533 2.399 -29.932 1.00 53.56 ? 341 HIS D C 1 ATOM 5165 O O . HIS D 2 171 ? 28.447 1.656 -30.308 1.00 54.08 ? 341 HIS D O 1 ATOM 5166 C CB . HIS D 2 171 ? 26.935 4.207 -28.262 1.00 51.55 ? 341 HIS D CB 1 ATOM 5167 C CG . HIS D 2 171 ? 27.269 5.540 -27.658 1.00 51.64 ? 341 HIS D CG 1 ATOM 5168 N ND1 . HIS D 2 171 ? 26.418 6.622 -27.730 1.00 52.03 ? 341 HIS D ND1 1 ATOM 5169 C CD2 . HIS D 2 171 ? 28.361 5.968 -26.978 1.00 52.17 ? 341 HIS D CD2 1 ATOM 5170 C CE1 . HIS D 2 171 ? 26.969 7.658 -27.121 1.00 51.57 ? 341 HIS D CE1 1 ATOM 5171 N NE2 . HIS D 2 171 ? 28.149 7.289 -26.655 1.00 51.47 ? 341 HIS D NE2 1 HETATM 5172 C C1 . NAG E 3 . ? 16.066 -13.606 -16.782 1.00 61.42 ? 166 NAG A C1 1 HETATM 5173 C C2 . NAG E 3 . ? 15.131 -13.335 -17.961 1.00 64.73 ? 166 NAG A C2 1 HETATM 5174 C C3 . NAG E 3 . ? 13.980 -12.431 -17.515 1.00 65.22 ? 166 NAG A C3 1 HETATM 5175 C C4 . NAG E 3 . ? 13.229 -13.063 -16.335 1.00 65.62 ? 166 NAG A C4 1 HETATM 5176 C C5 . NAG E 3 . ? 14.167 -13.652 -15.271 1.00 65.27 ? 166 NAG A C5 1 HETATM 5177 C C6 . NAG E 3 . ? 13.387 -14.626 -14.387 1.00 66.54 ? 166 NAG A C6 1 HETATM 5178 C C7 . NAG E 3 . ? 15.769 -13.389 -20.308 1.00 67.39 ? 166 NAG A C7 1 HETATM 5179 C C8 . NAG E 3 . ? 16.475 -14.702 -20.504 1.00 67.67 ? 166 NAG A C8 1 HETATM 5180 N N2 . NAG E 3 . ? 15.849 -12.806 -19.108 1.00 66.16 ? 166 NAG A N2 1 HETATM 5181 O O3 . NAG E 3 . ? 13.080 -12.233 -18.584 1.00 65.47 ? 166 NAG A O3 1 HETATM 5182 O O4 . NAG E 3 . ? 12.384 -12.109 -15.719 1.00 65.43 ? 166 NAG A O4 1 HETATM 5183 O O5 . NAG E 3 . ? 15.295 -14.322 -15.823 1.00 63.29 ? 166 NAG A O5 1 HETATM 5184 O O6 . NAG E 3 . ? 12.887 -13.945 -13.254 1.00 67.11 ? 166 NAG A O6 1 HETATM 5185 O O7 . NAG E 3 . ? 15.147 -12.891 -21.244 1.00 68.30 ? 166 NAG A O7 1 HETATM 5186 C C1 . LPQ F 4 . ? 24.523 -6.044 2.949 1.00 34.09 ? 167 LPQ A C1 1 HETATM 5187 C C2 . LPQ F 4 . ? 24.143 -6.355 4.402 1.00 34.63 ? 167 LPQ A C2 1 HETATM 5188 N N3 . LPQ F 4 . ? 25.164 -7.042 5.171 1.00 32.95 ? 167 LPQ A N3 1 HETATM 5189 C C4 . LPQ F 4 . ? 26.534 -6.542 5.081 1.00 35.63 ? 167 LPQ A C4 1 HETATM 5190 C C5 . LPQ F 4 . ? 26.958 -6.563 3.608 1.00 35.58 ? 167 LPQ A C5 1 HETATM 5191 C C6 . LPQ F 4 . ? 26.003 -5.714 2.733 1.00 34.73 ? 167 LPQ A C6 1 HETATM 5192 C C7 . LPQ F 4 . ? 26.406 -5.933 1.308 1.00 35.05 ? 167 LPQ A C7 1 HETATM 5193 C C8 . LPQ F 4 . ? 25.884 -6.964 0.515 1.00 33.54 ? 167 LPQ A C8 1 HETATM 5194 N N9 . LPQ F 4 . ? 26.298 -7.133 -0.757 1.00 33.84 ? 167 LPQ A N9 1 HETATM 5195 C C10 . LPQ F 4 . ? 27.255 -6.334 -1.305 1.00 34.60 ? 167 LPQ A C10 1 HETATM 5196 C C11 . LPQ F 4 . ? 27.808 -5.307 -0.549 1.00 34.84 ? 167 LPQ A C11 1 HETATM 5197 C C12 . LPQ F 4 . ? 27.386 -5.107 0.758 1.00 34.24 ? 167 LPQ A C12 1 HETATM 5198 O O13 . LPQ F 4 . ? 27.715 -6.478 -2.596 1.00 34.81 ? 167 LPQ A O13 1 HETATM 5199 C C14 . LPQ F 4 . ? 27.598 -7.675 -3.360 1.00 36.38 ? 167 LPQ A C14 1 HETATM 5200 C C15 . LPQ F 4 . ? 28.377 -6.137 3.284 1.00 35.66 ? 167 LPQ A C15 1 HETATM 5201 O O16 . LPQ F 4 . ? 28.751 -5.035 3.670 1.00 35.75 ? 167 LPQ A O16 1 HETATM 5202 N N17 . LPQ F 4 . ? 29.176 -6.938 2.536 1.00 35.03 ? 167 LPQ A N17 1 HETATM 5203 C C18 . LPQ F 4 . ? 28.881 -7.900 -4.151 1.00 37.51 ? 167 LPQ A C18 1 HETATM 5204 O O19 . LPQ F 4 . ? 29.464 -9.150 -3.752 1.00 39.26 ? 167 LPQ A O19 1 HETATM 5205 C C20 . LPQ F 4 . ? 30.819 -9.203 -3.571 1.00 40.31 ? 167 LPQ A C20 1 HETATM 5206 C C21 . LPQ F 4 . ? 31.633 -9.490 -4.645 1.00 40.08 ? 167 LPQ A C21 1 HETATM 5207 C C22 . LPQ F 4 . ? 33.018 -9.531 -4.506 1.00 40.15 ? 167 LPQ A C22 1 HETATM 5208 C C23 . LPQ F 4 . ? 33.579 -9.296 -3.256 1.00 40.03 ? 167 LPQ A C23 1 HETATM 5209 C C24 . LPQ F 4 . ? 32.769 -9.008 -2.166 1.00 39.28 ? 167 LPQ A C24 1 HETATM 5210 C C25 . LPQ F 4 . ? 31.390 -8.961 -2.334 1.00 39.96 ? 167 LPQ A C25 1 HETATM 5211 CL CL26 . LPQ F 4 . ? 30.850 -9.811 -6.203 1.00 40.69 ? 167 LPQ A CL26 1 HETATM 5212 CL CL27 . LPQ F 4 . ? 30.327 -8.594 -0.954 1.00 40.42 ? 167 LPQ A CL27 1 HETATM 5213 C C28 . LPQ F 4 . ? 35.070 -9.347 -3.083 1.00 40.27 ? 167 LPQ A C28 1 HETATM 5214 C C29 . LPQ F 4 . ? 30.513 -6.574 2.041 1.00 38.44 ? 167 LPQ A C29 1 HETATM 5215 C C30 . LPQ F 4 . ? 28.756 -8.248 1.984 1.00 33.93 ? 167 LPQ A C30 1 HETATM 5216 C C31 . LPQ F 4 . ? 31.750 -6.621 2.903 1.00 39.71 ? 167 LPQ A C31 1 HETATM 5217 C C32 . LPQ F 4 . ? 31.662 -6.833 4.267 1.00 40.97 ? 167 LPQ A C32 1 HETATM 5218 C C33 . LPQ F 4 . ? 32.820 -6.868 5.031 1.00 41.94 ? 167 LPQ A C33 1 HETATM 5219 C C34 . LPQ F 4 . ? 34.069 -6.694 4.447 1.00 41.51 ? 167 LPQ A C34 1 HETATM 5220 C C35 . LPQ F 4 . ? 34.161 -6.487 3.073 1.00 41.34 ? 167 LPQ A C35 1 HETATM 5221 C C36 . LPQ F 4 . ? 33.000 -6.452 2.309 1.00 40.85 ? 167 LPQ A C36 1 HETATM 5222 CL CL37 . LPQ F 4 . ? 33.170 -6.184 0.544 1.00 42.77 ? 167 LPQ A CL37 1 HETATM 5223 C C38 . LPQ F 4 . ? 32.709 -7.076 6.516 1.00 42.74 ? 167 LPQ A C38 1 HETATM 5224 N N39 . LPQ F 4 . ? 32.675 -5.773 7.188 1.00 47.32 ? 167 LPQ A N39 1 HETATM 5225 C C40 . LPQ F 4 . ? 28.507 -9.261 3.098 1.00 34.01 ? 167 LPQ A C40 1 HETATM 5226 C C41 . LPQ F 4 . ? 29.803 -9.324 2.313 1.00 32.00 ? 167 LPQ A C41 1 HETATM 5227 C C42 . LPQ F 4 . ? 31.618 -4.775 6.979 1.00 49.13 ? 167 LPQ A C42 1 HETATM 5228 C C43 . LPQ F 4 . ? 30.926 -4.406 8.291 1.00 48.94 ? 167 LPQ A C43 1 HETATM 5229 C C44 . LPQ F 4 . ? 30.226 -5.318 7.285 1.00 49.32 ? 167 LPQ A C44 1 HETATM 5230 C C1 . NAG G 3 . ? 46.661 7.811 -42.247 1.00 65.39 ? 166 NAG C C1 1 HETATM 5231 C C2 . NAG G 3 . ? 46.499 7.572 -43.753 1.00 68.92 ? 166 NAG C C2 1 HETATM 5232 C C3 . NAG G 3 . ? 45.197 6.827 -44.025 1.00 69.62 ? 166 NAG C C3 1 HETATM 5233 C C4 . NAG G 3 . ? 45.204 5.509 -43.254 1.00 69.79 ? 166 NAG C C4 1 HETATM 5234 C C5 . NAG G 3 . ? 45.448 5.753 -41.759 1.00 69.54 ? 166 NAG C C5 1 HETATM 5235 C C6 . NAG G 3 . ? 45.677 4.418 -41.048 1.00 71.14 ? 166 NAG C C6 1 HETATM 5236 C C7 . NAG G 3 . ? 47.262 8.888 -45.661 1.00 71.38 ? 166 NAG C C7 1 HETATM 5237 C C8 . NAG G 3 . ? 46.490 9.336 -46.872 1.00 72.45 ? 166 NAG C C8 1 HETATM 5238 N N2 . NAG G 3 . ? 46.570 8.808 -44.520 1.00 69.98 ? 166 NAG C N2 1 HETATM 5239 O O3 . NAG G 3 . ? 45.074 6.580 -45.408 1.00 70.99 ? 166 NAG C O3 1 HETATM 5240 O O4 . NAG G 3 . ? 43.984 4.825 -43.460 1.00 70.33 ? 166 NAG C O4 1 HETATM 5241 O O5 . NAG G 3 . ? 46.581 6.587 -41.531 1.00 67.80 ? 166 NAG C O5 1 HETATM 5242 O O6 . NAG G 3 . ? 46.432 4.588 -39.862 1.00 72.27 ? 166 NAG C O6 1 HETATM 5243 O O7 . NAG G 3 . ? 48.463 8.613 -45.756 1.00 70.92 ? 166 NAG C O7 1 HETATM 5244 C C1 . LPQ H 4 . ? 40.066 19.867 -11.761 1.00 43.19 ? 167 LPQ C C1 1 HETATM 5245 C C2 . LPQ H 4 . ? 38.830 20.277 -12.560 1.00 42.78 ? 167 LPQ C C2 1 HETATM 5246 N N3 . LPQ H 4 . ? 38.217 19.125 -13.199 1.00 44.30 ? 167 LPQ C N3 1 HETATM 5247 C C4 . LPQ H 4 . ? 37.842 17.955 -12.405 1.00 45.24 ? 167 LPQ C C4 1 HETATM 5248 C C5 . LPQ H 4 . ? 39.029 17.492 -11.557 1.00 43.70 ? 167 LPQ C C5 1 HETATM 5249 C C6 . LPQ H 4 . ? 39.732 18.684 -10.846 1.00 43.53 ? 167 LPQ C C6 1 HETATM 5250 C C7 . LPQ H 4 . ? 40.910 18.198 -10.069 1.00 42.75 ? 167 LPQ C C7 1 HETATM 5251 C C8 . LPQ H 4 . ? 42.165 17.977 -10.651 1.00 43.42 ? 167 LPQ C C8 1 HETATM 5252 N N9 . LPQ H 4 . ? 43.184 17.514 -9.900 1.00 43.85 ? 167 LPQ C N9 1 HETATM 5253 C C10 . LPQ H 4 . ? 43.024 17.236 -8.574 1.00 43.44 ? 167 LPQ C C10 1 HETATM 5254 C C11 . LPQ H 4 . ? 41.794 17.437 -7.950 1.00 43.05 ? 167 LPQ C C11 1 HETATM 5255 C C12 . LPQ H 4 . ? 40.736 17.921 -8.712 1.00 42.76 ? 167 LPQ C C12 1 HETATM 5256 O O13 . LPQ H 4 . ? 44.052 16.778 -7.799 1.00 43.56 ? 167 LPQ C O13 1 HETATM 5257 C C14 . LPQ H 4 . ? 45.202 16.125 -8.308 1.00 44.68 ? 167 LPQ C C14 1 HETATM 5258 C C15 . LPQ H 4 . ? 38.665 16.525 -10.452 1.00 43.24 ? 167 LPQ C C15 1 HETATM 5259 O O16 . LPQ H 4 . ? 37.818 16.869 -9.647 1.00 44.35 ? 167 LPQ C O16 1 HETATM 5260 N N17 . LPQ H 4 . ? 39.306 15.347 -10.328 1.00 42.49 ? 167 LPQ C N17 1 HETATM 5261 C C18 . LPQ H 4 . ? 45.480 14.931 -7.412 1.00 45.41 ? 167 LPQ C C18 1 HETATM 5262 O O19 . LPQ H 4 . ? 45.424 13.761 -8.216 1.00 47.61 ? 167 LPQ C O19 1 HETATM 5263 C C20 . LPQ H 4 . ? 44.897 12.596 -7.726 1.00 48.39 ? 167 LPQ C C20 1 HETATM 5264 C C21 . LPQ H 4 . ? 45.730 11.744 -7.017 1.00 48.73 ? 167 LPQ C C21 1 HETATM 5265 C C22 . LPQ H 4 . ? 45.233 10.550 -6.505 1.00 48.64 ? 167 LPQ C C22 1 HETATM 5266 C C23 . LPQ H 4 . ? 43.897 10.216 -6.716 1.00 48.79 ? 167 LPQ C C23 1 HETATM 5267 C C24 . LPQ H 4 . ? 43.055 11.067 -7.425 1.00 48.91 ? 167 LPQ C C24 1 HETATM 5268 C C25 . LPQ H 4 . ? 43.560 12.261 -7.933 1.00 48.81 ? 167 LPQ C C25 1 HETATM 5269 CL CL26 . LPQ H 4 . ? 47.451 12.205 -6.779 1.00 49.83 ? 167 LPQ C CL26 1 HETATM 5270 CL CL27 . LPQ H 4 . ? 42.468 13.346 -8.857 1.00 48.67 ? 167 LPQ C CL27 1 HETATM 5271 C C28 . LPQ H 4 . ? 43.353 8.936 -6.162 1.00 48.50 ? 167 LPQ C C28 1 HETATM 5272 C C29 . LPQ H 4 . ? 39.114 14.387 -9.228 1.00 46.81 ? 167 LPQ C C29 1 HETATM 5273 C C30 . LPQ H 4 . ? 40.359 14.940 -11.274 1.00 40.97 ? 167 LPQ C C30 1 HETATM 5274 C C31 . LPQ H 4 . ? 38.004 13.370 -9.280 1.00 47.93 ? 167 LPQ C C31 1 HETATM 5275 C C32 . LPQ H 4 . ? 37.088 13.397 -10.312 1.00 49.65 ? 167 LPQ C C32 1 HETATM 5276 C C33 . LPQ H 4 . ? 36.066 12.466 -10.369 1.00 49.68 ? 167 LPQ C C33 1 HETATM 5277 C C34 . LPQ H 4 . ? 35.952 11.492 -9.374 1.00 49.24 ? 167 LPQ C C34 1 HETATM 5278 C C35 . LPQ H 4 . ? 36.873 11.461 -8.319 1.00 49.11 ? 167 LPQ C C35 1 HETATM 5279 C C36 . LPQ H 4 . ? 37.901 12.407 -8.281 1.00 49.42 ? 167 LPQ C C36 1 HETATM 5280 CL CL37 . LPQ H 4 . ? 39.111 12.385 -6.950 1.00 50.60 ? 167 LPQ C CL37 1 HETATM 5281 C C38 . LPQ H 4 . ? 35.134 12.561 -11.557 1.00 49.87 ? 167 LPQ C C38 1 HETATM 5282 N N39 . LPQ H 4 . ? 35.951 12.506 -12.781 1.00 50.20 ? 167 LPQ C N39 1 HETATM 5283 C C40 . LPQ H 4 . ? 39.634 14.392 -12.508 1.00 39.83 ? 167 LPQ C C40 1 HETATM 5284 C C41 . LPQ H 4 . ? 40.332 13.436 -11.561 1.00 38.23 ? 167 LPQ C C41 1 HETATM 5285 C C42 . LPQ H 4 . ? 35.792 11.424 -13.745 1.00 50.64 ? 167 LPQ C C42 1 HETATM 5286 C C43 . LPQ H 4 . ? 36.867 11.403 -14.827 1.00 50.21 ? 167 LPQ C C43 1 HETATM 5287 C C44 . LPQ H 4 . ? 35.489 11.961 -15.148 1.00 50.35 ? 167 LPQ C C44 1 HETATM 5288 O O . HOH I 5 . ? 23.109 -10.262 -1.457 1.00 36.27 ? 168 HOH A O 1 HETATM 5289 O O . HOH I 5 . ? 37.592 -2.324 -7.963 1.00 29.90 ? 169 HOH A O 1 HETATM 5290 O O . HOH I 5 . ? 9.427 -27.418 0.457 1.00 50.27 ? 170 HOH A O 1 HETATM 5291 O O . HOH I 5 . ? 17.296 -27.443 -8.091 1.00 30.13 ? 171 HOH A O 1 HETATM 5292 O O . HOH I 5 . ? 32.922 -24.598 -14.572 1.00 26.20 ? 172 HOH A O 1 HETATM 5293 O O . HOH I 5 . ? 26.722 -15.985 -22.205 1.00 42.35 ? 173 HOH A O 1 HETATM 5294 O O . HOH I 5 . ? 10.654 -26.655 9.237 1.00 43.63 ? 174 HOH A O 1 HETATM 5295 O O . HOH I 5 . ? 16.426 -16.815 1.684 1.00 43.02 ? 175 HOH A O 1 HETATM 5296 O O . HOH I 5 . ? 29.295 -15.930 6.445 1.00 25.77 ? 176 HOH A O 1 HETATM 5297 O O . HOH I 5 . ? 20.516 -14.476 -6.435 1.00 24.48 ? 177 HOH A O 1 HETATM 5298 O O . HOH I 5 . ? 18.734 -17.386 0.500 1.00 38.22 ? 178 HOH A O 1 HETATM 5299 O O . HOH I 5 . ? 20.800 -12.458 -8.054 1.00 44.33 ? 179 HOH A O 1 HETATM 5300 O O . HOH I 5 . ? 38.852 -12.831 19.251 1.00 26.42 ? 180 HOH A O 1 HETATM 5301 O O . HOH I 5 . ? 17.283 -18.662 -8.070 1.00 32.21 ? 181 HOH A O 1 HETATM 5302 O O . HOH I 5 . ? 31.601 -15.412 -17.566 1.00 32.39 ? 182 HOH A O 1 HETATM 5303 O O . HOH I 5 . ? 43.297 -2.875 -11.447 1.00 41.91 ? 183 HOH A O 1 HETATM 5304 O O . HOH I 5 . ? 15.753 -10.315 3.978 1.00 33.37 ? 184 HOH A O 1 HETATM 5305 O O . HOH I 5 . ? 32.686 -26.500 -2.682 1.00 45.78 ? 185 HOH A O 1 HETATM 5306 O O . HOH I 5 . ? 12.128 -15.393 0.370 1.00 34.86 ? 186 HOH A O 1 HETATM 5307 O O . HOH I 5 . ? 36.284 2.827 -3.821 1.00 39.94 ? 187 HOH A O 1 HETATM 5308 O O . HOH I 5 . ? 24.033 -14.554 -18.268 1.00 32.37 ? 188 HOH A O 1 HETATM 5309 O O . HOH I 5 . ? 20.632 -15.745 -2.477 1.00 29.09 ? 189 HOH A O 1 HETATM 5310 O O . HOH I 5 . ? 42.438 -18.441 16.201 1.00 46.94 ? 190 HOH A O 1 HETATM 5311 O O . HOH I 5 . ? 37.200 -6.128 7.145 1.00 27.74 ? 191 HOH A O 1 HETATM 5312 O O . HOH I 5 . ? 14.380 -28.187 1.517 1.00 45.21 ? 192 HOH A O 1 HETATM 5313 O O . HOH I 5 . ? 32.982 -27.142 4.630 1.00 32.20 ? 193 HOH A O 1 HETATM 5314 O O . HOH I 5 . ? 21.546 -24.040 -15.151 1.00 31.86 ? 194 HOH A O 1 HETATM 5315 O O . HOH I 5 . ? 31.472 -11.527 7.731 1.00 41.35 ? 195 HOH A O 1 HETATM 5316 O O . HOH I 5 . ? 37.368 -24.271 -8.879 1.00 27.39 ? 196 HOH A O 1 HETATM 5317 O O . HOH I 5 . ? 17.385 -9.598 6.325 1.00 31.77 ? 197 HOH A O 1 HETATM 5318 O O . HOH I 5 . ? 16.204 -25.039 -7.844 1.00 32.88 ? 198 HOH A O 1 HETATM 5319 O O . HOH I 5 . ? 35.423 -24.108 17.965 1.00 43.36 ? 199 HOH A O 1 HETATM 5320 O O . HOH I 5 . ? 30.446 -26.086 0.436 1.00 32.67 ? 200 HOH A O 1 HETATM 5321 O O . HOH I 5 . ? 23.830 -24.997 -20.429 1.00 32.54 ? 201 HOH A O 1 HETATM 5322 O O . HOH I 5 . ? 18.675 -3.515 -10.434 1.00 48.97 ? 202 HOH A O 1 HETATM 5323 O O . HOH I 5 . ? 39.728 -19.402 10.713 1.00 34.60 ? 203 HOH A O 1 HETATM 5324 O O . HOH I 5 . ? 35.943 -12.783 23.003 1.00 63.11 ? 204 HOH A O 1 HETATM 5325 O O . HOH I 5 . ? 37.309 -22.670 -0.969 1.00 45.86 ? 205 HOH A O 1 HETATM 5326 O O . HOH I 5 . ? 28.751 -26.291 -8.918 1.00 41.65 ? 206 HOH A O 1 HETATM 5327 O O . HOH I 5 . ? 9.436 -13.016 -16.850 1.00 54.55 ? 207 HOH A O 1 HETATM 5328 O O . HOH I 5 . ? 22.146 -25.173 -22.706 1.00 39.37 ? 208 HOH A O 1 HETATM 5329 O O . HOH I 5 . ? 26.911 -5.686 -16.779 1.00 39.36 ? 209 HOH A O 1 HETATM 5330 O O . HOH I 5 . ? 16.192 -17.263 4.106 1.00 35.85 ? 210 HOH A O 1 HETATM 5331 O O . HOH I 5 . ? 18.095 -14.044 -5.265 1.00 34.18 ? 211 HOH A O 1 HETATM 5332 O O . HOH I 5 . ? 17.107 -37.708 9.086 1.00 49.58 ? 212 HOH A O 1 HETATM 5333 O O . HOH I 5 . ? 24.474 -1.511 0.088 1.00 60.26 ? 213 HOH A O 1 HETATM 5334 O O . HOH I 5 . ? 33.716 -24.067 3.398 1.00 39.25 ? 214 HOH A O 1 HETATM 5335 O O . HOH I 5 . ? 38.703 -18.779 14.992 1.00 43.29 ? 215 HOH A O 1 HETATM 5336 O O . HOH I 5 . ? 36.416 -19.574 -11.724 1.00 34.33 ? 216 HOH A O 1 HETATM 5337 O O . HOH I 5 . ? 27.628 -13.121 -20.823 1.00 57.45 ? 217 HOH A O 1 HETATM 5338 O O . HOH I 5 . ? 14.569 -4.689 -7.782 1.00 42.53 ? 218 HOH A O 1 HETATM 5339 O O . HOH I 5 . ? 25.875 -30.446 -17.586 1.00 33.58 ? 219 HOH A O 1 HETATM 5340 O O . HOH I 5 . ? 34.059 -3.611 7.126 1.00 44.47 ? 220 HOH A O 1 HETATM 5341 O O . HOH I 5 . ? 39.648 -16.585 -11.440 1.00 31.07 ? 221 HOH A O 1 HETATM 5342 O O . HOH I 5 . ? 29.422 -16.353 -22.004 1.00 31.89 ? 222 HOH A O 1 HETATM 5343 O O . HOH J 5 . ? 26.662 -23.933 13.124 1.00 29.02 ? 9 HOH B O 1 HETATM 5344 O O . HOH J 5 . ? 29.834 -17.376 23.679 1.00 34.30 ? 13 HOH B O 1 HETATM 5345 O O . HOH J 5 . ? 13.617 4.219 22.233 1.00 58.67 ? 22 HOH B O 1 HETATM 5346 O O . HOH J 5 . ? 23.031 0.462 12.393 1.00 22.87 ? 25 HOH B O 1 HETATM 5347 O O . HOH J 5 . ? 16.290 1.831 15.701 1.00 43.12 ? 28 HOH B O 1 HETATM 5348 O O . HOH J 5 . ? 28.912 -18.063 17.458 1.00 28.31 ? 29 HOH B O 1 HETATM 5349 O O . HOH J 5 . ? 9.299 -16.738 18.758 1.00 40.55 ? 33 HOH B O 1 HETATM 5350 O O . HOH J 5 . ? 32.743 -5.683 30.593 1.00 28.79 ? 34 HOH B O 1 HETATM 5351 O O . HOH J 5 . ? 11.721 -18.907 23.540 1.00 35.14 ? 35 HOH B O 1 HETATM 5352 O O . HOH J 5 . ? 30.380 -28.723 23.334 1.00 74.57 ? 38 HOH B O 1 HETATM 5353 O O . HOH J 5 . ? 29.372 -3.056 33.644 1.00 42.54 ? 51 HOH B O 1 HETATM 5354 O O . HOH J 5 . ? 11.096 -8.033 10.318 1.00 42.66 ? 52 HOH B O 1 HETATM 5355 O O . HOH J 5 . ? 23.951 -12.465 28.257 1.00 30.52 ? 57 HOH B O 1 HETATM 5356 O O . HOH J 5 . ? 42.555 -2.172 18.449 1.00 35.80 ? 58 HOH B O 1 HETATM 5357 O O . HOH J 5 . ? 32.452 -10.806 20.192 1.00 32.74 ? 60 HOH B O 1 HETATM 5358 O O . HOH J 5 . ? 24.911 -4.438 30.540 1.00 37.57 ? 66 HOH B O 1 HETATM 5359 O O . HOH J 5 . ? 44.588 -22.410 13.784 1.00 42.67 ? 75 HOH B O 1 HETATM 5360 O O . HOH J 5 . ? 10.279 -8.699 17.081 1.00 34.61 ? 79 HOH B O 1 HETATM 5361 O O . HOH J 5 . ? 17.687 3.158 19.885 1.00 38.10 ? 81 HOH B O 1 HETATM 5362 O O . HOH J 5 . ? 12.336 -8.413 21.358 1.00 41.93 ? 82 HOH B O 1 HETATM 5363 O O . HOH J 5 . ? 11.367 -24.801 11.581 1.00 47.59 ? 87 HOH B O 1 HETATM 5364 O O . HOH J 5 . ? 13.319 -7.639 25.780 1.00 46.74 ? 91 HOH B O 1 HETATM 5365 O O . HOH J 5 . ? 33.811 -8.136 14.960 1.00 32.95 ? 92 HOH B O 1 HETATM 5366 O O . HOH J 5 . ? 32.030 4.416 14.071 1.00 38.21 ? 102 HOH B O 1 HETATM 5367 O O . HOH J 5 . ? 9.460 -17.475 6.230 1.00 30.79 ? 104 HOH B O 1 HETATM 5368 O O . HOH J 5 . ? 37.812 -23.798 23.588 1.00 50.51 ? 109 HOH B O 1 HETATM 5369 O O . HOH J 5 . ? 15.373 -13.757 23.778 1.00 39.76 ? 110 HOH B O 1 HETATM 5370 O O . HOH J 5 . ? 22.333 -28.006 24.003 1.00 37.35 ? 123 HOH B O 1 HETATM 5371 O O . HOH J 5 . ? 15.591 5.926 24.448 1.00 44.96 ? 124 HOH B O 1 HETATM 5372 O O . HOH J 5 . ? 17.616 -30.389 12.028 1.00 49.67 ? 135 HOH B O 1 HETATM 5373 O O . HOH J 5 . ? 34.626 1.343 16.134 1.00 38.78 ? 138 HOH B O 1 HETATM 5374 O O . HOH J 5 . ? 19.114 -3.790 27.847 1.00 53.85 ? 152 HOH B O 1 HETATM 5375 O O . HOH J 5 . ? 6.968 -23.782 5.857 1.00 37.80 ? 156 HOH B O 1 HETATM 5376 O O . HOH J 5 . ? 8.323 -12.620 19.768 1.00 35.93 ? 157 HOH B O 1 HETATM 5377 O O . HOH J 5 . ? 20.168 6.072 11.133 1.00 41.11 ? 158 HOH B O 1 HETATM 5378 O O . HOH J 5 . ? 20.177 3.277 11.205 1.00 38.00 ? 161 HOH B O 1 HETATM 5379 O O . HOH J 5 . ? 19.104 -29.723 14.259 1.00 40.31 ? 169 HOH B O 1 HETATM 5380 O O . HOH J 5 . ? 9.870 2.961 19.663 1.00 45.11 ? 347 HOH B O 1 HETATM 5381 O O . HOH J 5 . ? 21.424 -16.489 26.098 1.00 48.18 ? 348 HOH B O 1 HETATM 5382 O O . HOH J 5 . ? 35.339 -10.424 29.808 1.00 50.37 ? 349 HOH B O 1 HETATM 5383 O O . HOH J 5 . ? 46.883 7.364 31.017 1.00 47.68 ? 350 HOH B O 1 HETATM 5384 O O . HOH J 5 . ? 6.521 -12.927 11.950 1.00 45.03 ? 351 HOH B O 1 HETATM 5385 O O . HOH J 5 . ? 32.244 -12.478 28.496 1.00 51.89 ? 352 HOH B O 1 HETATM 5386 O O . HOH K 5 . ? 42.205 10.798 6.815 1.00 54.03 ? 168 HOH C O 1 HETATM 5387 O O . HOH K 5 . ? 43.754 11.026 2.322 1.00 45.80 ? 169 HOH C O 1 HETATM 5388 O O . HOH K 5 . ? 39.765 10.502 -18.719 1.00 26.79 ? 170 HOH C O 1 HETATM 5389 O O . HOH K 5 . ? 65.735 21.597 -9.703 1.00 40.51 ? 171 HOH C O 1 HETATM 5390 O O . HOH K 5 . ? 49.795 25.188 -23.007 1.00 43.85 ? 172 HOH C O 1 HETATM 5391 O O . HOH K 5 . ? 52.259 20.377 -16.124 1.00 32.62 ? 173 HOH C O 1 HETATM 5392 O O . HOH K 5 . ? 49.918 17.654 -18.011 1.00 24.29 ? 174 HOH C O 1 HETATM 5393 O O . HOH K 5 . ? 49.256 6.160 -36.506 1.00 35.76 ? 175 HOH C O 1 HETATM 5394 O O . HOH K 5 . ? 48.732 18.412 -21.325 1.00 38.48 ? 176 HOH C O 1 HETATM 5395 O O . HOH K 5 . ? 58.939 8.359 -4.655 1.00 54.32 ? 177 HOH C O 1 HETATM 5396 O O . HOH K 5 . ? 49.733 2.375 -1.079 1.00 37.56 ? 178 HOH C O 1 HETATM 5397 O O . HOH K 5 . ? 27.772 -1.937 -20.298 1.00 51.74 ? 179 HOH C O 1 HETATM 5398 O O . HOH K 5 . ? 46.493 22.395 -12.975 1.00 38.98 ? 180 HOH C O 1 HETATM 5399 O O . HOH K 5 . ? 39.225 3.527 -4.097 1.00 46.89 ? 181 HOH C O 1 HETATM 5400 O O . HOH K 5 . ? 46.099 18.151 -13.067 1.00 35.00 ? 182 HOH C O 1 HETATM 5401 O O . HOH K 5 . ? 31.189 2.341 -21.332 1.00 38.51 ? 183 HOH C O 1 HETATM 5402 O O . HOH K 5 . ? 47.503 20.815 -36.065 1.00 36.77 ? 184 HOH C O 1 HETATM 5403 O O . HOH K 5 . ? 51.706 2.964 -23.505 1.00 38.55 ? 185 HOH C O 1 HETATM 5404 O O . HOH K 5 . ? 68.205 12.587 -9.067 1.00 39.25 ? 186 HOH C O 1 HETATM 5405 O O . HOH K 5 . ? 64.496 18.758 -12.422 1.00 46.15 ? 187 HOH C O 1 HETATM 5406 O O . HOH K 5 . ? 40.981 23.926 -19.169 1.00 35.53 ? 188 HOH C O 1 HETATM 5407 O O . HOH K 5 . ? 34.883 -0.059 -19.359 1.00 25.35 ? 189 HOH C O 1 HETATM 5408 O O . HOH K 5 . ? 51.983 0.869 -4.486 1.00 32.04 ? 190 HOH C O 1 HETATM 5409 O O . HOH K 5 . ? 44.329 1.119 -7.319 1.00 51.51 ? 191 HOH C O 1 HETATM 5410 O O . HOH K 5 . ? 38.259 22.813 -5.615 1.00 55.78 ? 192 HOH C O 1 HETATM 5411 O O . HOH K 5 . ? 60.248 14.262 -24.536 1.00 30.77 ? 193 HOH C O 1 HETATM 5412 O O . HOH K 5 . ? 52.431 25.587 -5.502 1.00 51.04 ? 194 HOH C O 1 HETATM 5413 O O . HOH K 5 . ? 32.527 9.259 -9.001 1.00 26.71 ? 195 HOH C O 1 HETATM 5414 O O . HOH K 5 . ? 62.731 23.373 -11.807 1.00 69.13 ? 196 HOH C O 1 HETATM 5415 O O . HOH K 5 . ? 28.053 11.071 -15.491 1.00 31.35 ? 197 HOH C O 1 HETATM 5416 O O . HOH K 5 . ? 57.731 4.998 -18.603 1.00 51.85 ? 198 HOH C O 1 HETATM 5417 O O . HOH K 5 . ? 25.043 5.671 -19.877 1.00 46.65 ? 199 HOH C O 1 HETATM 5418 O O . HOH K 5 . ? 58.539 21.371 -17.299 1.00 45.59 ? 200 HOH C O 1 HETATM 5419 O O . HOH K 5 . ? 53.035 12.034 3.954 1.00 42.24 ? 201 HOH C O 1 HETATM 5420 O O . HOH K 5 . ? 47.878 12.195 8.402 1.00 67.26 ? 202 HOH C O 1 HETATM 5421 O O . HOH K 5 . ? 61.417 12.161 -23.672 1.00 39.54 ? 203 HOH C O 1 HETATM 5422 O O . HOH K 5 . ? 48.467 20.839 -22.438 1.00 37.90 ? 204 HOH C O 1 HETATM 5423 O O . HOH K 5 . ? 52.858 18.107 -14.814 1.00 38.33 ? 205 HOH C O 1 HETATM 5424 O O . HOH K 5 . ? 42.405 4.227 -45.497 1.00 56.60 ? 206 HOH C O 1 HETATM 5425 O O . HOH K 5 . ? 53.566 9.235 -40.156 1.00 44.19 ? 207 HOH C O 1 HETATM 5426 O O . HOH K 5 . ? 40.890 17.843 -37.152 1.00 41.20 ? 208 HOH C O 1 HETATM 5427 O O . HOH K 5 . ? 38.355 14.481 3.688 1.00 37.92 ? 209 HOH C O 1 HETATM 5428 O O . HOH K 5 . ? 26.373 7.364 -11.551 1.00 51.25 ? 210 HOH C O 1 HETATM 5429 O O . HOH K 5 . ? 53.684 6.291 7.337 1.00 66.88 ? 211 HOH C O 1 HETATM 5430 O O . HOH K 5 . ? 48.876 5.669 -44.219 1.00 52.00 ? 212 HOH C O 1 HETATM 5431 O O . HOH L 5 . ? 31.747 10.105 -26.511 1.00 24.58 ? 1 HOH D O 1 HETATM 5432 O O . HOH L 5 . ? 29.052 24.915 -13.159 1.00 44.22 ? 14 HOH D O 1 HETATM 5433 O O . HOH L 5 . ? 38.523 8.725 -29.590 1.00 31.83 ? 16 HOH D O 1 HETATM 5434 O O . HOH L 5 . ? 26.029 9.923 -29.201 1.00 30.67 ? 18 HOH D O 1 HETATM 5435 O O . HOH L 5 . ? 43.799 25.140 -19.110 1.00 27.67 ? 20 HOH D O 1 HETATM 5436 O O . HOH L 5 . ? 33.360 30.680 -27.659 1.00 30.06 ? 43 HOH D O 1 HETATM 5437 O O . HOH L 5 . ? 29.007 30.099 -28.861 1.00 33.93 ? 44 HOH D O 1 HETATM 5438 O O . HOH L 5 . ? 21.522 23.049 -34.714 1.00 38.12 ? 48 HOH D O 1 HETATM 5439 O O . HOH L 5 . ? 27.994 15.012 -35.760 1.00 32.77 ? 63 HOH D O 1 HETATM 5440 O O . HOH L 5 . ? 28.607 19.193 -34.475 1.00 50.86 ? 65 HOH D O 1 HETATM 5441 O O . HOH L 5 . ? 23.713 27.864 -34.125 1.00 57.65 ? 68 HOH D O 1 HETATM 5442 O O . HOH L 5 . ? 29.706 25.655 -35.050 1.00 35.97 ? 69 HOH D O 1 HETATM 5443 O O . HOH L 5 . ? 23.762 36.777 -18.669 1.00 56.56 ? 76 HOH D O 1 HETATM 5444 O O . HOH L 5 . ? 44.930 13.434 -37.603 1.00 40.74 ? 78 HOH D O 1 HETATM 5445 O O . HOH L 5 . ? 29.901 28.512 -11.781 1.00 38.18 ? 83 HOH D O 1 HETATM 5446 O O . HOH L 5 . ? 34.484 16.733 -39.808 1.00 33.71 ? 88 HOH D O 1 HETATM 5447 O O . HOH L 5 . ? 28.713 31.656 -17.253 1.00 55.58 ? 94 HOH D O 1 HETATM 5448 O O . HOH L 5 . ? 38.738 29.971 -23.484 1.00 49.37 ? 101 HOH D O 1 HETATM 5449 O O . HOH L 5 . ? 22.030 13.854 -2.320 1.00 64.99 ? 111 HOH D O 1 HETATM 5450 O O . HOH L 5 . ? 40.643 20.488 -36.261 1.00 33.69 ? 114 HOH D O 1 HETATM 5451 O O . HOH L 5 . ? 39.736 28.776 -34.880 1.00 28.45 ? 115 HOH D O 1 HETATM 5452 O O . HOH L 5 . ? 44.700 29.417 -32.882 1.00 45.09 ? 116 HOH D O 1 HETATM 5453 O O . HOH L 5 . ? 46.547 21.279 -23.998 1.00 31.65 ? 119 HOH D O 1 HETATM 5454 O O . HOH L 5 . ? 14.338 23.500 -8.551 1.00 56.46 ? 122 HOH D O 1 HETATM 5455 O O . HOH L 5 . ? 34.057 19.353 -39.851 1.00 31.49 ? 125 HOH D O 1 HETATM 5456 O O . HOH L 5 . ? 31.610 3.867 -31.331 1.00 46.15 ? 126 HOH D O 1 HETATM 5457 O O . HOH L 5 . ? 28.851 23.878 -33.061 1.00 36.28 ? 128 HOH D O 1 HETATM 5458 O O . HOH L 5 . ? 24.614 29.964 -8.240 1.00 50.02 ? 131 HOH D O 1 HETATM 5459 O O . HOH L 5 . ? 17.988 7.458 -4.900 1.00 57.32 ? 132 HOH D O 1 HETATM 5460 O O . HOH L 5 . ? 27.601 -0.750 -29.726 1.00 39.28 ? 136 HOH D O 1 HETATM 5461 O O . HOH L 5 . ? 10.699 20.762 -29.543 1.00 55.68 ? 137 HOH D O 1 HETATM 5462 O O . HOH L 5 . ? 30.881 -4.229 -21.495 1.00 51.49 ? 142 HOH D O 1 HETATM 5463 O O . HOH L 5 . ? 31.893 16.320 -11.526 1.00 37.56 ? 149 HOH D O 1 HETATM 5464 O O . HOH L 5 . ? 25.144 11.391 -21.522 1.00 40.49 ? 154 HOH D O 1 HETATM 5465 O O . HOH L 5 . ? 22.982 34.753 -20.134 1.00 55.13 ? 347 HOH D O 1 HETATM 5466 O O . HOH L 5 . ? 33.560 30.205 -32.322 1.00 40.25 ? 348 HOH D O 1 HETATM 5467 O O . HOH L 5 . ? 36.580 15.114 -38.893 1.00 51.38 ? 349 HOH D O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 LEU 1 1 ? ? ? A . n A 1 2 THR 2 2 ? ? ? A . n A 1 3 LEU 3 3 ? ? ? A . n A 1 4 GLY 4 4 4 GLY GLY A . n A 1 5 ASN 5 5 5 ASN ASN A . n A 1 6 THR 6 6 6 THR THR A . n A 1 7 THR 7 7 7 THR THR A . n A 1 8 SER 8 8 8 SER SER A . n A 1 9 SER 9 9 9 SER SER A . n A 1 10 VAL 10 10 10 VAL VAL A . n A 1 11 ILE 11 11 11 ILE ILE A . n A 1 12 LEU 12 12 12 LEU LEU A . n A 1 13 THR 13 13 13 THR THR A . n A 1 14 ASN 14 14 14 ASN ASN A . n A 1 15 TYR 15 15 15 TYR TYR A . n A 1 16 MET 16 16 16 MET MET A . n A 1 17 ASP 17 17 17 ASP ASP A . n A 1 18 THR 18 18 18 THR THR A . n A 1 19 GLN 19 19 19 GLN GLN A . n A 1 20 TYR 20 20 20 TYR TYR A . n A 1 21 TYR 21 21 21 TYR TYR A . n A 1 22 GLY 22 22 22 GLY GLY A . n A 1 23 GLU 23 23 23 GLU GLU A . n A 1 24 ILE 24 24 24 ILE ILE A . n A 1 25 GLY 25 25 25 GLY GLY A . n A 1 26 ILE 26 26 26 ILE ILE A . n A 1 27 GLY 27 27 27 GLY GLY A . n A 1 28 THR 28 28 28 THR THR A . n A 1 29 PRO 29 29 29 PRO PRO A . n A 1 30 PRO 30 30 30 PRO PRO A . n A 1 31 GLN 31 31 31 GLN GLN A . n A 1 32 THR 32 32 32 THR THR A . n A 1 33 PHE 33 33 33 PHE PHE A . n A 1 34 LYS 34 34 34 LYS LYS A . n A 1 35 VAL 35 35 35 VAL VAL A . n A 1 36 VAL 36 36 36 VAL VAL A . n A 1 37 PHE 37 37 37 PHE PHE A . n A 1 38 ASP 38 38 38 ASP ASP A . n A 1 39 THR 39 39 39 THR THR A . n A 1 40 GLY 40 40 40 GLY GLY A . n A 1 41 SER 41 41 41 SER SER A . n A 1 42 SER 42 42 42 SER SER A . n A 1 43 ASN 43 43 43 ASN ASN A . n A 1 44 VAL 44 44 44 VAL VAL A . n A 1 45 TRP 45 45 45 TRP TRP A . n A 1 46 VAL 46 46 46 VAL VAL A . n A 1 47 PRO 47 47 47 PRO PRO A . n A 1 48 SER 48 48 48 SER SER A . n A 1 49 SER 49 49 49 SER SER A . n A 1 50 LYS 50 50 50 LYS LYS A . n A 1 51 CYS 51 51 51 CYS CYS A . n A 1 52 SER 52 52 52 SER SER A . n A 1 53 ARG 53 53 53 ARG ARG A . n A 1 54 LEU 54 54 54 LEU LEU A . n A 1 55 TYR 55 55 55 TYR TYR A . n A 1 56 THR 56 56 56 THR THR A . n A 1 57 ALA 57 57 57 ALA ALA A . n A 1 58 CYS 58 58 58 CYS CYS A . n A 1 59 VAL 59 59 59 VAL VAL A . n A 1 60 TYR 60 60 60 TYR TYR A . n A 1 61 HIS 61 61 61 HIS HIS A . n A 1 62 LYS 62 62 62 LYS LYS A . n A 1 63 LEU 63 63 63 LEU LEU A . n A 1 64 PHE 64 64 64 PHE PHE A . n A 1 65 ASP 65 65 65 ASP ASP A . n A 1 66 ALA 66 66 66 ALA ALA A . n A 1 67 SER 67 67 67 SER SER A . n A 1 68 ASP 68 68 68 ASP ASP A . n A 1 69 SER 69 69 69 SER SER A . n A 1 70 SER 70 70 70 SER SER A . n A 1 71 SER 71 71 71 SER SER A . n A 1 72 TYR 72 72 72 TYR TYR A . n A 1 73 LYS 73 73 73 LYS LYS A . n A 1 74 HIS 74 74 74 HIS HIS A . n A 1 75 ASN 75 75 75 ASN ASN A . n A 1 76 GLY 76 76 76 GLY GLY A . n A 1 77 THR 77 77 77 THR THR A . n A 1 78 GLU 78 78 78 GLU GLU A . n A 1 79 LEU 79 79 79 LEU LEU A . n A 1 80 THR 80 80 80 THR THR A . n A 1 81 LEU 81 81 81 LEU LEU A . n A 1 82 ARG 82 82 82 ARG ARG A . n A 1 83 TYR 83 83 83 TYR TYR A . n A 1 84 SER 84 84 84 SER SER A . n A 1 85 THR 85 85 85 THR THR A . n A 1 86 GLY 86 86 86 GLY GLY A . n A 1 87 THR 87 87 87 THR THR A . n A 1 88 VAL 88 88 88 VAL VAL A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 GLY 90 90 90 GLY GLY A . n A 1 91 PHE 91 91 91 PHE PHE A . n A 1 92 LEU 92 92 92 LEU LEU A . n A 1 93 SER 93 93 93 SER SER A . n A 1 94 GLN 94 94 94 GLN GLN A . n A 1 95 ASP 95 95 95 ASP ASP A . n A 1 96 ILE 96 96 96 ILE ILE A . n A 1 97 ILE 97 97 97 ILE ILE A . n A 1 98 THR 98 98 98 THR THR A . n A 1 99 VAL 99 99 99 VAL VAL A . n A 1 100 GLY 100 100 100 GLY GLY A . n A 1 101 GLY 101 101 101 GLY GLY A . n A 1 102 ILE 102 102 102 ILE ILE A . n A 1 103 THR 103 103 103 THR THR A . n A 1 104 VAL 104 104 104 VAL VAL A . n A 1 105 THR 105 105 105 THR THR A . n A 1 106 GLN 106 106 106 GLN GLN A . n A 1 107 MET 107 107 107 MET MET A . n A 1 108 PHE 108 108 108 PHE PHE A . n A 1 109 GLY 109 109 109 GLY GLY A . n A 1 110 GLU 110 110 110 GLU GLU A . n A 1 111 VAL 111 111 111 VAL VAL A . n A 1 112 THR 112 112 112 THR THR A . n A 1 113 GLU 113 113 113 GLU GLU A . n A 1 114 MET 114 114 114 MET MET A . n A 1 115 PRO 115 115 115 PRO PRO A . n A 1 116 ALA 116 116 116 ALA ALA A . n A 1 117 LEU 117 117 117 LEU LEU A . n A 1 118 PRO 118 118 118 PRO PRO A . n A 1 119 PHE 119 119 119 PHE PHE A . n A 1 120 MET 120 120 120 MET MET A . n A 1 121 LEU 121 121 121 LEU LEU A . n A 1 122 ALA 122 122 122 ALA ALA A . n A 1 123 GLU 123 123 123 GLU GLU A . n A 1 124 PHE 124 124 124 PHE PHE A . n A 1 125 ASP 125 125 125 ASP ASP A . n A 1 126 GLY 126 126 126 GLY GLY A . n A 1 127 VAL 127 127 127 VAL VAL A . n A 1 128 VAL 128 128 128 VAL VAL A . n A 1 129 GLY 129 129 129 GLY GLY A . n A 1 130 MET 130 130 130 MET MET A . n A 1 131 GLY 131 131 131 GLY GLY A . n A 1 132 PHE 132 132 132 PHE PHE A . n A 1 133 ILE 133 133 133 ILE ILE A . n A 1 134 GLU 134 134 134 GLU GLU A . n A 1 135 GLN 135 135 135 GLN GLN A . n A 1 136 ALA 136 136 136 ALA ALA A . n A 1 137 ILE 137 137 137 ILE ILE A . n A 1 138 GLY 138 138 138 GLY GLY A . n A 1 139 ARG 139 139 139 ARG ARG A . n A 1 140 VAL 140 140 140 VAL VAL A . n A 1 141 THR 141 141 141 THR THR A . n A 1 142 PRO 142 142 142 PRO PRO A . n A 1 143 ILE 143 143 143 ILE ILE A . n A 1 144 PHE 144 144 144 PHE PHE A . n A 1 145 ASP 145 145 145 ASP ASP A . n A 1 146 ASN 146 146 146 ASN ASN A . n A 1 147 ILE 147 147 147 ILE ILE A . n A 1 148 ILE 148 148 148 ILE ILE A . n A 1 149 SER 149 149 149 SER SER A . n A 1 150 GLN 150 150 150 GLN GLN A . n A 1 151 GLY 151 151 151 GLY GLY A . n A 1 152 VAL 152 152 152 VAL VAL A . n A 1 153 LEU 153 153 153 LEU LEU A . n A 1 154 LYS 154 154 154 LYS LYS A . n A 1 155 GLU 155 155 155 GLU GLU A . n A 1 156 ASP 156 156 156 ASP ASP A . n A 1 157 VAL 157 157 157 VAL VAL A . n A 1 158 PHE 158 158 158 PHE PHE A . n A 1 159 SER 159 159 159 SER SER A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 TYR 161 161 161 TYR TYR A . n A 1 162 TYR 162 162 162 TYR TYR A . n A 1 163 ASN 163 163 163 ASN ASN A . n A 1 164 ARG 164 164 164 ARG ARG A . n A 1 165 ASP 165 165 165 ASP ASP A . n A 1 166 SER 166 166 ? ? ? A . n B 2 1 SER 1 171 171 SER SER B . n B 2 2 LEU 2 172 172 LEU LEU B . n B 2 3 GLY 3 173 173 GLY GLY B . n B 2 4 GLY 4 174 174 GLY GLY B . n B 2 5 GLN 5 175 175 GLN GLN B . n B 2 6 ILE 6 176 176 ILE ILE B . n B 2 7 VAL 7 177 177 VAL VAL B . n B 2 8 LEU 8 178 178 LEU LEU B . n B 2 9 GLY 9 179 179 GLY GLY B . n B 2 10 GLY 10 180 180 GLY GLY B . n B 2 11 SER 11 181 181 SER SER B . n B 2 12 ASP 12 182 182 ASP ASP B . n B 2 13 PRO 13 183 183 PRO PRO B . n B 2 14 GLN 14 184 184 GLN GLN B . n B 2 15 HIS 15 185 185 HIS HIS B . n B 2 16 TYR 16 186 186 TYR TYR B . n B 2 17 GLU 17 187 187 GLU GLU B . n B 2 18 GLY 18 188 188 GLY GLY B . n B 2 19 ASN 19 189 189 ASN ASN B . n B 2 20 PHE 20 190 190 PHE PHE B . n B 2 21 HIS 21 191 191 HIS HIS B . n B 2 22 TYR 22 192 192 TYR TYR B . n B 2 23 ILE 23 193 193 ILE ILE B . n B 2 24 ASN 24 194 194 ASN ASN B . n B 2 25 LEU 25 195 195 LEU LEU B . n B 2 26 ILE 26 196 196 ILE ILE B . n B 2 27 LYS 27 197 197 LYS LYS B . n B 2 28 THR 28 198 198 THR THR B . n B 2 29 GLY 29 199 199 GLY GLY B . n B 2 30 VAL 30 200 200 VAL VAL B . n B 2 31 TRP 31 201 201 TRP TRP B . n B 2 32 GLN 32 202 202 GLN GLN B . n B 2 33 ILE 33 203 203 ILE ILE B . n B 2 34 GLN 34 204 204 GLN GLN B . n B 2 35 MET 35 205 205 MET MET B . n B 2 36 LYS 36 206 206 LYS LYS B . n B 2 37 GLY 37 207 207 GLY GLY B . n B 2 38 VAL 38 208 208 VAL VAL B . n B 2 39 SER 39 209 209 SER SER B . n B 2 40 VAL 40 210 210 VAL VAL B . n B 2 41 GLY 41 211 211 GLY GLY B . n B 2 42 SER 42 212 212 SER SER B . n B 2 43 SER 43 213 213 SER SER B . n B 2 44 THR 44 214 214 THR THR B . n B 2 45 LEU 45 215 215 LEU LEU B . n B 2 46 LEU 46 216 216 LEU LEU B . n B 2 47 CYS 47 217 217 CYS CYS B . n B 2 48 GLU 48 218 218 GLU GLU B . n B 2 49 ASP 49 219 219 ASP ASP B . n B 2 50 GLY 50 220 220 GLY GLY B . n B 2 51 CYS 51 221 221 CYS CYS B . n B 2 52 LEU 52 222 222 LEU LEU B . n B 2 53 ALA 53 223 223 ALA ALA B . n B 2 54 LEU 54 224 224 LEU LEU B . n B 2 55 VAL 55 225 225 VAL VAL B . n B 2 56 ASP 56 226 226 ASP ASP B . n B 2 57 THR 57 227 227 THR THR B . n B 2 58 GLY 58 228 228 GLY GLY B . n B 2 59 ALA 59 229 229 ALA ALA B . n B 2 60 SER 60 230 230 SER SER B . n B 2 61 TYR 61 231 231 TYR TYR B . n B 2 62 ILE 62 232 232 ILE ILE B . n B 2 63 SER 63 233 233 SER SER B . n B 2 64 GLY 64 234 234 GLY GLY B . n B 2 65 SER 65 235 235 SER SER B . n B 2 66 THR 66 236 236 THR THR B . n B 2 67 SER 67 237 237 SER SER B . n B 2 68 SER 68 238 238 SER SER B . n B 2 69 ILE 69 239 239 ILE ILE B . n B 2 70 GLU 70 240 240 GLU GLU B . n B 2 71 LYS 71 241 241 LYS LYS B . n B 2 72 LEU 72 242 242 LEU LEU B . n B 2 73 MET 73 243 243 MET MET B . n B 2 74 GLU 74 244 244 GLU GLU B . n B 2 75 ALA 75 245 245 ALA ALA B . n B 2 76 LEU 76 246 246 LEU LEU B . n B 2 77 GLY 77 247 247 GLY GLY B . n B 2 78 ALA 78 248 248 ALA ALA B . n B 2 79 LYS 79 249 249 LYS LYS B . n B 2 80 LYS 80 250 250 LYS LYS B . n B 2 81 ARG 81 251 251 ARG ARG B . n B 2 82 LEU 82 252 252 LEU LEU B . n B 2 83 PHE 83 253 253 PHE PHE B . n B 2 84 ASP 84 254 254 ASP ASP B . n B 2 85 TYR 85 255 255 TYR TYR B . n B 2 86 VAL 86 256 256 VAL VAL B . n B 2 87 VAL 87 257 257 VAL VAL B . n B 2 88 LYS 88 258 258 LYS LYS B . n B 2 89 CYS 89 259 259 CYS CYS B . n B 2 90 ASN 90 260 260 ASN ASN B . n B 2 91 GLU 91 261 261 GLU GLU B . n B 2 92 GLY 92 262 262 GLY GLY B . n B 2 93 PRO 93 263 263 PRO PRO B . n B 2 94 THR 94 264 264 THR THR B . n B 2 95 LEU 95 265 265 LEU LEU B . n B 2 96 PRO 96 266 266 PRO PRO B . n B 2 97 ASP 97 267 267 ASP ASP B . n B 2 98 ILE 98 268 268 ILE ILE B . n B 2 99 SER 99 269 269 SER SER B . n B 2 100 PHE 100 270 270 PHE PHE B . n B 2 101 HIS 101 271 271 HIS HIS B . n B 2 102 LEU 102 272 272 LEU LEU B . n B 2 103 GLY 103 273 273 GLY GLY B . n B 2 104 GLY 104 274 274 GLY GLY B . n B 2 105 LYS 105 275 275 LYS LYS B . n B 2 106 GLU 106 276 276 GLU GLU B . n B 2 107 TYR 107 277 277 TYR TYR B . n B 2 108 THR 108 278 278 THR THR B . n B 2 109 LEU 109 279 279 LEU LEU B . n B 2 110 THR 110 280 280 THR THR B . n B 2 111 SER 111 281 281 SER SER B . n B 2 112 ALA 112 282 282 ALA ALA B . n B 2 113 ASP 113 283 283 ASP ASP B . n B 2 114 TYR 114 284 284 TYR TYR B . n B 2 115 VAL 115 285 285 VAL VAL B . n B 2 116 PHE 116 286 286 PHE PHE B . n B 2 117 GLN 117 287 287 GLN GLN B . n B 2 118 GLU 118 288 288 GLU GLU B . n B 2 119 SER 119 289 289 SER SER B . n B 2 120 TYR 120 290 290 TYR TYR B . n B 2 121 SER 121 291 291 SER SER B . n B 2 122 SER 122 292 292 SER SER B . n B 2 123 LYS 123 293 293 LYS LYS B . n B 2 124 LYS 124 294 294 LYS LYS B . n B 2 125 LEU 125 295 295 LEU LEU B . n B 2 126 CYS 126 296 296 CYS CYS B . n B 2 127 THR 127 297 297 THR THR B . n B 2 128 LEU 128 298 298 LEU LEU B . n B 2 129 ALA 129 299 299 ALA ALA B . n B 2 130 ILE 130 300 300 ILE ILE B . n B 2 131 HIS 131 301 301 HIS HIS B . n B 2 132 ALA 132 302 302 ALA ALA B . n B 2 133 MET 133 303 303 MET MET B . n B 2 134 ASP 134 304 304 ASP ASP B . n B 2 135 ILE 135 305 305 ILE ILE B . n B 2 136 PRO 136 306 306 PRO PRO B . n B 2 137 PRO 137 307 307 PRO PRO B . n B 2 138 PRO 138 308 308 PRO PRO B . n B 2 139 THR 139 309 309 THR THR B . n B 2 140 GLY 140 310 310 GLY GLY B . n B 2 141 PRO 141 311 311 PRO PRO B . n B 2 142 THR 142 312 312 THR THR B . n B 2 143 TRP 143 313 313 TRP TRP B . n B 2 144 ALA 144 314 314 ALA ALA B . n B 2 145 LEU 145 315 315 LEU LEU B . n B 2 146 GLY 146 316 316 GLY GLY B . n B 2 147 ALA 147 317 317 ALA ALA B . n B 2 148 THR 148 318 318 THR THR B . n B 2 149 PHE 149 319 319 PHE PHE B . n B 2 150 ILE 150 320 320 ILE ILE B . n B 2 151 ARG 151 321 321 ARG ARG B . n B 2 152 LYS 152 322 322 LYS LYS B . n B 2 153 PHE 153 323 323 PHE PHE B . n B 2 154 TYR 154 324 324 TYR TYR B . n B 2 155 THR 155 325 325 THR THR B . n B 2 156 GLU 156 326 326 GLU GLU B . n B 2 157 PHE 157 327 327 PHE PHE B . n B 2 158 ASP 158 328 328 ASP ASP B . n B 2 159 ARG 159 329 329 ARG ARG B . n B 2 160 ARG 160 330 330 ARG ARG B . n B 2 161 ASN 161 331 331 ASN ASN B . n B 2 162 ASN 162 332 332 ASN ASN B . n B 2 163 ARG 163 333 333 ARG ARG B . n B 2 164 ILE 164 334 334 ILE ILE B . n B 2 165 GLY 165 335 335 GLY GLY B . n B 2 166 PHE 166 336 336 PHE PHE B . n B 2 167 ALA 167 337 337 ALA ALA B . n B 2 168 LEU 168 338 338 LEU LEU B . n B 2 169 ALA 169 339 339 ALA ALA B . n B 2 170 ARG 170 340 340 ARG ARG B . n B 2 171 HIS 171 341 341 HIS HIS B . n B 2 172 HIS 172 342 ? ? ? B . n B 2 173 HIS 173 343 ? ? ? B . n B 2 174 HIS 174 344 ? ? ? B . n B 2 175 HIS 175 345 ? ? ? B . n B 2 176 HIS 176 346 ? ? ? B . n C 1 1 LEU 1 1 1 LEU LEU C . n C 1 2 THR 2 2 2 THR THR C . n C 1 3 LEU 3 3 3 LEU LEU C . n C 1 4 GLY 4 4 4 GLY GLY C . n C 1 5 ASN 5 5 5 ASN ASN C . n C 1 6 THR 6 6 6 THR THR C . n C 1 7 THR 7 7 7 THR THR C . n C 1 8 SER 8 8 8 SER SER C . n C 1 9 SER 9 9 9 SER SER C . n C 1 10 VAL 10 10 10 VAL VAL C . n C 1 11 ILE 11 11 11 ILE ILE C . n C 1 12 LEU 12 12 12 LEU LEU C . n C 1 13 THR 13 13 13 THR THR C . n C 1 14 ASN 14 14 14 ASN ASN C . n C 1 15 TYR 15 15 15 TYR TYR C . n C 1 16 MET 16 16 16 MET MET C . n C 1 17 ASP 17 17 17 ASP ASP C . n C 1 18 THR 18 18 18 THR THR C . n C 1 19 GLN 19 19 19 GLN GLN C . n C 1 20 TYR 20 20 20 TYR TYR C . n C 1 21 TYR 21 21 21 TYR TYR C . n C 1 22 GLY 22 22 22 GLY GLY C . n C 1 23 GLU 23 23 23 GLU GLU C . n C 1 24 ILE 24 24 24 ILE ILE C . n C 1 25 GLY 25 25 25 GLY GLY C . n C 1 26 ILE 26 26 26 ILE ILE C . n C 1 27 GLY 27 27 27 GLY GLY C . n C 1 28 THR 28 28 28 THR THR C . n C 1 29 PRO 29 29 29 PRO PRO C . n C 1 30 PRO 30 30 30 PRO PRO C . n C 1 31 GLN 31 31 31 GLN GLN C . n C 1 32 THR 32 32 32 THR THR C . n C 1 33 PHE 33 33 33 PHE PHE C . n C 1 34 LYS 34 34 34 LYS LYS C . n C 1 35 VAL 35 35 35 VAL VAL C . n C 1 36 VAL 36 36 36 VAL VAL C . n C 1 37 PHE 37 37 37 PHE PHE C . n C 1 38 ASP 38 38 38 ASP ASP C . n C 1 39 THR 39 39 39 THR THR C . n C 1 40 GLY 40 40 40 GLY GLY C . n C 1 41 SER 41 41 41 SER SER C . n C 1 42 SER 42 42 42 SER SER C . n C 1 43 ASN 43 43 43 ASN ASN C . n C 1 44 VAL 44 44 44 VAL VAL C . n C 1 45 TRP 45 45 45 TRP TRP C . n C 1 46 VAL 46 46 46 VAL VAL C . n C 1 47 PRO 47 47 47 PRO PRO C . n C 1 48 SER 48 48 48 SER SER C . n C 1 49 SER 49 49 49 SER SER C . n C 1 50 LYS 50 50 50 LYS LYS C . n C 1 51 CYS 51 51 51 CYS CYS C . n C 1 52 SER 52 52 52 SER SER C . n C 1 53 ARG 53 53 53 ARG ARG C . n C 1 54 LEU 54 54 54 LEU LEU C . n C 1 55 TYR 55 55 55 TYR TYR C . n C 1 56 THR 56 56 56 THR THR C . n C 1 57 ALA 57 57 57 ALA ALA C . n C 1 58 CYS 58 58 58 CYS CYS C . n C 1 59 VAL 59 59 59 VAL VAL C . n C 1 60 TYR 60 60 60 TYR TYR C . n C 1 61 HIS 61 61 61 HIS HIS C . n C 1 62 LYS 62 62 62 LYS LYS C . n C 1 63 LEU 63 63 63 LEU LEU C . n C 1 64 PHE 64 64 64 PHE PHE C . n C 1 65 ASP 65 65 65 ASP ASP C . n C 1 66 ALA 66 66 66 ALA ALA C . n C 1 67 SER 67 67 67 SER SER C . n C 1 68 ASP 68 68 68 ASP ASP C . n C 1 69 SER 69 69 69 SER SER C . n C 1 70 SER 70 70 70 SER SER C . n C 1 71 SER 71 71 71 SER SER C . n C 1 72 TYR 72 72 72 TYR TYR C . n C 1 73 LYS 73 73 73 LYS LYS C . n C 1 74 HIS 74 74 74 HIS HIS C . n C 1 75 ASN 75 75 75 ASN ASN C . n C 1 76 GLY 76 76 76 GLY GLY C . n C 1 77 THR 77 77 77 THR THR C . n C 1 78 GLU 78 78 78 GLU GLU C . n C 1 79 LEU 79 79 79 LEU LEU C . n C 1 80 THR 80 80 80 THR THR C . n C 1 81 LEU 81 81 81 LEU LEU C . n C 1 82 ARG 82 82 82 ARG ARG C . n C 1 83 TYR 83 83 83 TYR TYR C . n C 1 84 SER 84 84 84 SER SER C . n C 1 85 THR 85 85 85 THR THR C . n C 1 86 GLY 86 86 86 GLY GLY C . n C 1 87 THR 87 87 87 THR THR C . n C 1 88 VAL 88 88 88 VAL VAL C . n C 1 89 SER 89 89 89 SER SER C . n C 1 90 GLY 90 90 90 GLY GLY C . n C 1 91 PHE 91 91 91 PHE PHE C . n C 1 92 LEU 92 92 92 LEU LEU C . n C 1 93 SER 93 93 93 SER SER C . n C 1 94 GLN 94 94 94 GLN GLN C . n C 1 95 ASP 95 95 95 ASP ASP C . n C 1 96 ILE 96 96 96 ILE ILE C . n C 1 97 ILE 97 97 97 ILE ILE C . n C 1 98 THR 98 98 98 THR THR C . n C 1 99 VAL 99 99 99 VAL VAL C . n C 1 100 GLY 100 100 100 GLY GLY C . n C 1 101 GLY 101 101 101 GLY GLY C . n C 1 102 ILE 102 102 102 ILE ILE C . n C 1 103 THR 103 103 103 THR THR C . n C 1 104 VAL 104 104 104 VAL VAL C . n C 1 105 THR 105 105 105 THR THR C . n C 1 106 GLN 106 106 106 GLN GLN C . n C 1 107 MET 107 107 107 MET MET C . n C 1 108 PHE 108 108 108 PHE PHE C . n C 1 109 GLY 109 109 109 GLY GLY C . n C 1 110 GLU 110 110 110 GLU GLU C . n C 1 111 VAL 111 111 111 VAL VAL C . n C 1 112 THR 112 112 112 THR THR C . n C 1 113 GLU 113 113 113 GLU GLU C . n C 1 114 MET 114 114 114 MET MET C . n C 1 115 PRO 115 115 115 PRO PRO C . n C 1 116 ALA 116 116 116 ALA ALA C . n C 1 117 LEU 117 117 117 LEU LEU C . n C 1 118 PRO 118 118 118 PRO PRO C . n C 1 119 PHE 119 119 119 PHE PHE C . n C 1 120 MET 120 120 120 MET MET C . n C 1 121 LEU 121 121 121 LEU LEU C . n C 1 122 ALA 122 122 122 ALA ALA C . n C 1 123 GLU 123 123 123 GLU GLU C . n C 1 124 PHE 124 124 124 PHE PHE C . n C 1 125 ASP 125 125 125 ASP ASP C . n C 1 126 GLY 126 126 126 GLY GLY C . n C 1 127 VAL 127 127 127 VAL VAL C . n C 1 128 VAL 128 128 128 VAL VAL C . n C 1 129 GLY 129 129 129 GLY GLY C . n C 1 130 MET 130 130 130 MET MET C . n C 1 131 GLY 131 131 131 GLY GLY C . n C 1 132 PHE 132 132 132 PHE PHE C . n C 1 133 ILE 133 133 133 ILE ILE C . n C 1 134 GLU 134 134 134 GLU GLU C . n C 1 135 GLN 135 135 135 GLN GLN C . n C 1 136 ALA 136 136 136 ALA ALA C . n C 1 137 ILE 137 137 137 ILE ILE C . n C 1 138 GLY 138 138 138 GLY GLY C . n C 1 139 ARG 139 139 139 ARG ARG C . n C 1 140 VAL 140 140 140 VAL VAL C . n C 1 141 THR 141 141 141 THR THR C . n C 1 142 PRO 142 142 142 PRO PRO C . n C 1 143 ILE 143 143 143 ILE ILE C . n C 1 144 PHE 144 144 144 PHE PHE C . n C 1 145 ASP 145 145 145 ASP ASP C . n C 1 146 ASN 146 146 146 ASN ASN C . n C 1 147 ILE 147 147 147 ILE ILE C . n C 1 148 ILE 148 148 148 ILE ILE C . n C 1 149 SER 149 149 149 SER SER C . n C 1 150 GLN 150 150 150 GLN GLN C . n C 1 151 GLY 151 151 151 GLY GLY C . n C 1 152 VAL 152 152 152 VAL VAL C . n C 1 153 LEU 153 153 153 LEU LEU C . n C 1 154 LYS 154 154 154 LYS LYS C . n C 1 155 GLU 155 155 155 GLU GLU C . n C 1 156 ASP 156 156 156 ASP ASP C . n C 1 157 VAL 157 157 157 VAL VAL C . n C 1 158 PHE 158 158 158 PHE PHE C . n C 1 159 SER 159 159 159 SER SER C . n C 1 160 PHE 160 160 160 PHE PHE C . n C 1 161 TYR 161 161 161 TYR TYR C . n C 1 162 TYR 162 162 162 TYR TYR C . n C 1 163 ASN 163 163 163 ASN ASN C . n C 1 164 ARG 164 164 164 ARG ARG C . n C 1 165 ASP 165 165 165 ASP ASP C . n C 1 166 SER 166 166 ? ? ? C . n D 2 1 SER 1 171 171 SER SER D . n D 2 2 LEU 2 172 172 LEU LEU D . n D 2 3 GLY 3 173 173 GLY GLY D . n D 2 4 GLY 4 174 174 GLY GLY D . n D 2 5 GLN 5 175 175 GLN GLN D . n D 2 6 ILE 6 176 176 ILE ILE D . n D 2 7 VAL 7 177 177 VAL VAL D . n D 2 8 LEU 8 178 178 LEU LEU D . n D 2 9 GLY 9 179 179 GLY GLY D . n D 2 10 GLY 10 180 180 GLY GLY D . n D 2 11 SER 11 181 181 SER SER D . n D 2 12 ASP 12 182 182 ASP ASP D . n D 2 13 PRO 13 183 183 PRO PRO D . n D 2 14 GLN 14 184 184 GLN GLN D . n D 2 15 HIS 15 185 185 HIS HIS D . n D 2 16 TYR 16 186 186 TYR TYR D . n D 2 17 GLU 17 187 187 GLU GLU D . n D 2 18 GLY 18 188 188 GLY GLY D . n D 2 19 ASN 19 189 189 ASN ASN D . n D 2 20 PHE 20 190 190 PHE PHE D . n D 2 21 HIS 21 191 191 HIS HIS D . n D 2 22 TYR 22 192 192 TYR TYR D . n D 2 23 ILE 23 193 193 ILE ILE D . n D 2 24 ASN 24 194 194 ASN ASN D . n D 2 25 LEU 25 195 195 LEU LEU D . n D 2 26 ILE 26 196 196 ILE ILE D . n D 2 27 LYS 27 197 197 LYS LYS D . n D 2 28 THR 28 198 198 THR THR D . n D 2 29 GLY 29 199 199 GLY GLY D . n D 2 30 VAL 30 200 200 VAL VAL D . n D 2 31 TRP 31 201 201 TRP TRP D . n D 2 32 GLN 32 202 202 GLN GLN D . n D 2 33 ILE 33 203 203 ILE ILE D . n D 2 34 GLN 34 204 204 GLN GLN D . n D 2 35 MET 35 205 205 MET MET D . n D 2 36 LYS 36 206 206 LYS LYS D . n D 2 37 GLY 37 207 207 GLY GLY D . n D 2 38 VAL 38 208 208 VAL VAL D . n D 2 39 SER 39 209 209 SER SER D . n D 2 40 VAL 40 210 210 VAL VAL D . n D 2 41 GLY 41 211 211 GLY GLY D . n D 2 42 SER 42 212 212 SER SER D . n D 2 43 SER 43 213 213 SER SER D . n D 2 44 THR 44 214 214 THR THR D . n D 2 45 LEU 45 215 215 LEU LEU D . n D 2 46 LEU 46 216 216 LEU LEU D . n D 2 47 CYS 47 217 217 CYS CYS D . n D 2 48 GLU 48 218 218 GLU GLU D . n D 2 49 ASP 49 219 219 ASP ASP D . n D 2 50 GLY 50 220 220 GLY GLY D . n D 2 51 CYS 51 221 221 CYS CYS D . n D 2 52 LEU 52 222 222 LEU LEU D . n D 2 53 ALA 53 223 223 ALA ALA D . n D 2 54 LEU 54 224 224 LEU LEU D . n D 2 55 VAL 55 225 225 VAL VAL D . n D 2 56 ASP 56 226 226 ASP ASP D . n D 2 57 THR 57 227 227 THR THR D . n D 2 58 GLY 58 228 228 GLY GLY D . n D 2 59 ALA 59 229 229 ALA ALA D . n D 2 60 SER 60 230 230 SER SER D . n D 2 61 TYR 61 231 231 TYR TYR D . n D 2 62 ILE 62 232 232 ILE ILE D . n D 2 63 SER 63 233 233 SER SER D . n D 2 64 GLY 64 234 234 GLY GLY D . n D 2 65 SER 65 235 235 SER SER D . n D 2 66 THR 66 236 236 THR THR D . n D 2 67 SER 67 237 237 SER SER D . n D 2 68 SER 68 238 238 SER SER D . n D 2 69 ILE 69 239 239 ILE ILE D . n D 2 70 GLU 70 240 240 GLU GLU D . n D 2 71 LYS 71 241 241 LYS LYS D . n D 2 72 LEU 72 242 242 LEU LEU D . n D 2 73 MET 73 243 243 MET MET D . n D 2 74 GLU 74 244 244 GLU GLU D . n D 2 75 ALA 75 245 245 ALA ALA D . n D 2 76 LEU 76 246 246 LEU LEU D . n D 2 77 GLY 77 247 247 GLY GLY D . n D 2 78 ALA 78 248 248 ALA ALA D . n D 2 79 LYS 79 249 249 LYS LYS D . n D 2 80 LYS 80 250 250 LYS LYS D . n D 2 81 ARG 81 251 251 ARG ARG D . n D 2 82 LEU 82 252 252 LEU LEU D . n D 2 83 PHE 83 253 253 PHE PHE D . n D 2 84 ASP 84 254 254 ASP ASP D . n D 2 85 TYR 85 255 255 TYR TYR D . n D 2 86 VAL 86 256 256 VAL VAL D . n D 2 87 VAL 87 257 257 VAL VAL D . n D 2 88 LYS 88 258 258 LYS LYS D . n D 2 89 CYS 89 259 259 CYS CYS D . n D 2 90 ASN 90 260 260 ASN ASN D . n D 2 91 GLU 91 261 261 GLU GLU D . n D 2 92 GLY 92 262 262 GLY GLY D . n D 2 93 PRO 93 263 263 PRO PRO D . n D 2 94 THR 94 264 264 THR THR D . n D 2 95 LEU 95 265 265 LEU LEU D . n D 2 96 PRO 96 266 266 PRO PRO D . n D 2 97 ASP 97 267 267 ASP ASP D . n D 2 98 ILE 98 268 268 ILE ILE D . n D 2 99 SER 99 269 269 SER SER D . n D 2 100 PHE 100 270 270 PHE PHE D . n D 2 101 HIS 101 271 271 HIS HIS D . n D 2 102 LEU 102 272 272 LEU LEU D . n D 2 103 GLY 103 273 273 GLY GLY D . n D 2 104 GLY 104 274 274 GLY GLY D . n D 2 105 LYS 105 275 275 LYS LYS D . n D 2 106 GLU 106 276 276 GLU GLU D . n D 2 107 TYR 107 277 277 TYR TYR D . n D 2 108 THR 108 278 278 THR THR D . n D 2 109 LEU 109 279 279 LEU LEU D . n D 2 110 THR 110 280 280 THR THR D . n D 2 111 SER 111 281 281 SER SER D . n D 2 112 ALA 112 282 282 ALA ALA D . n D 2 113 ASP 113 283 283 ASP ASP D . n D 2 114 TYR 114 284 284 TYR TYR D . n D 2 115 VAL 115 285 285 VAL VAL D . n D 2 116 PHE 116 286 286 PHE PHE D . n D 2 117 GLN 117 287 287 GLN GLN D . n D 2 118 GLU 118 288 288 GLU GLU D . n D 2 119 SER 119 289 289 SER SER D . n D 2 120 TYR 120 290 290 TYR TYR D . n D 2 121 SER 121 291 291 SER SER D . n D 2 122 SER 122 292 292 SER SER D . n D 2 123 LYS 123 293 293 LYS LYS D . n D 2 124 LYS 124 294 294 LYS LYS D . n D 2 125 LEU 125 295 295 LEU LEU D . n D 2 126 CYS 126 296 296 CYS CYS D . n D 2 127 THR 127 297 297 THR THR D . n D 2 128 LEU 128 298 298 LEU LEU D . n D 2 129 ALA 129 299 299 ALA ALA D . n D 2 130 ILE 130 300 300 ILE ILE D . n D 2 131 HIS 131 301 301 HIS HIS D . n D 2 132 ALA 132 302 302 ALA ALA D . n D 2 133 MET 133 303 303 MET MET D . n D 2 134 ASP 134 304 304 ASP ASP D . n D 2 135 ILE 135 305 305 ILE ILE D . n D 2 136 PRO 136 306 306 PRO PRO D . n D 2 137 PRO 137 307 307 PRO PRO D . n D 2 138 PRO 138 308 308 PRO PRO D . n D 2 139 THR 139 309 309 THR THR D . n D 2 140 GLY 140 310 310 GLY GLY D . n D 2 141 PRO 141 311 311 PRO PRO D . n D 2 142 THR 142 312 312 THR THR D . n D 2 143 TRP 143 313 313 TRP TRP D . n D 2 144 ALA 144 314 314 ALA ALA D . n D 2 145 LEU 145 315 315 LEU LEU D . n D 2 146 GLY 146 316 316 GLY GLY D . n D 2 147 ALA 147 317 317 ALA ALA D . n D 2 148 THR 148 318 318 THR THR D . n D 2 149 PHE 149 319 319 PHE PHE D . n D 2 150 ILE 150 320 320 ILE ILE D . n D 2 151 ARG 151 321 321 ARG ARG D . n D 2 152 LYS 152 322 322 LYS LYS D . n D 2 153 PHE 153 323 323 PHE PHE D . n D 2 154 TYR 154 324 324 TYR TYR D . n D 2 155 THR 155 325 325 THR THR D . n D 2 156 GLU 156 326 326 GLU GLU D . n D 2 157 PHE 157 327 327 PHE PHE D . n D 2 158 ASP 158 328 328 ASP ASP D . n D 2 159 ARG 159 329 329 ARG ARG D . n D 2 160 ARG 160 330 330 ARG ARG D . n D 2 161 ASN 161 331 331 ASN ASN D . n D 2 162 ASN 162 332 332 ASN ASN D . n D 2 163 ARG 163 333 333 ARG ARG D . n D 2 164 ILE 164 334 334 ILE ILE D . n D 2 165 GLY 165 335 335 GLY GLY D . n D 2 166 PHE 166 336 336 PHE PHE D . n D 2 167 ALA 167 337 337 ALA ALA D . n D 2 168 LEU 168 338 338 LEU LEU D . n D 2 169 ALA 169 339 339 ALA ALA D . n D 2 170 ARG 170 340 340 ARG ARG D . n D 2 171 HIS 171 341 341 HIS HIS D . n D 2 172 HIS 172 342 ? ? ? D . n D 2 173 HIS 173 343 ? ? ? D . n D 2 174 HIS 174 344 ? ? ? D . n D 2 175 HIS 175 345 ? ? ? D . n D 2 176 HIS 176 346 ? ? ? D . n # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 75 A ASN 75 ? ASN 'GLYCOSYLATION SITE' 2 C ASN 5 C ASN 5 ? ASN 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA dimeric 2 2 author_and_software_defined_assembly PISA dimeric 2 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,B,E,F,I,J 2 1 C,D,G,H,K,L # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 4150 ? 1 MORE -16 ? 1 'SSA (A^2)' 14680 ? 2 'ABSA (A^2)' 3940 ? 2 MORE -18 ? 2 'SSA (A^2)' 15200 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2010-11-03 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal MAR345dtb 'data collection' . ? 1 MOLREP phasing . ? 2 REFMAC refinement 5.2.0019 ? 3 MOSFLM 'data reduction' . ? 4 SCALA 'data scaling' . ? 5 # _pdbx_entry_details.entry_id 3OAG _pdbx_entry_details.nonpolymer_details ? _pdbx_entry_details.sequence_details 'A PRESEQUENCE COMPOSED OF FOUR RESIDUES (-233ESN236Q-) HAS BEEN CLEAVED AWAY TO ACTIVATE THE PROTEASE' _pdbx_entry_details.compound_details ? _pdbx_entry_details.source_details ? # _pdbx_validate_close_contact.id 1 _pdbx_validate_close_contact.PDB_model_num 1 _pdbx_validate_close_contact.auth_atom_id_1 ND2 _pdbx_validate_close_contact.auth_asym_id_1 C _pdbx_validate_close_contact.auth_comp_id_1 ASN _pdbx_validate_close_contact.auth_seq_id_1 5 _pdbx_validate_close_contact.PDB_ins_code_1 ? _pdbx_validate_close_contact.label_alt_id_1 ? _pdbx_validate_close_contact.auth_atom_id_2 C2 _pdbx_validate_close_contact.auth_asym_id_2 C _pdbx_validate_close_contact.auth_comp_id_2 NAG _pdbx_validate_close_contact.auth_seq_id_2 166 _pdbx_validate_close_contact.PDB_ins_code_2 ? _pdbx_validate_close_contact.label_alt_id_2 ? _pdbx_validate_close_contact.dist 2.04 # _pdbx_validate_rmsd_angle.id 1 _pdbx_validate_rmsd_angle.PDB_model_num 1 _pdbx_validate_rmsd_angle.auth_atom_id_1 N _pdbx_validate_rmsd_angle.auth_asym_id_1 C _pdbx_validate_rmsd_angle.auth_comp_id_1 ASN _pdbx_validate_rmsd_angle.auth_seq_id_1 5 _pdbx_validate_rmsd_angle.PDB_ins_code_1 ? _pdbx_validate_rmsd_angle.label_alt_id_1 ? _pdbx_validate_rmsd_angle.auth_atom_id_2 CA _pdbx_validate_rmsd_angle.auth_asym_id_2 C _pdbx_validate_rmsd_angle.auth_comp_id_2 ASN _pdbx_validate_rmsd_angle.auth_seq_id_2 5 _pdbx_validate_rmsd_angle.PDB_ins_code_2 ? _pdbx_validate_rmsd_angle.label_alt_id_2 ? _pdbx_validate_rmsd_angle.auth_atom_id_3 C _pdbx_validate_rmsd_angle.auth_asym_id_3 C _pdbx_validate_rmsd_angle.auth_comp_id_3 ASN _pdbx_validate_rmsd_angle.auth_seq_id_3 5 _pdbx_validate_rmsd_angle.PDB_ins_code_3 ? _pdbx_validate_rmsd_angle.label_alt_id_3 ? _pdbx_validate_rmsd_angle.angle_value 134.00 _pdbx_validate_rmsd_angle.angle_target_value 111.00 _pdbx_validate_rmsd_angle.angle_deviation 23.00 _pdbx_validate_rmsd_angle.angle_standard_deviation 2.70 _pdbx_validate_rmsd_angle.linker_flag N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASN A 75 ? ? -132.37 -61.39 2 1 ARG A 139 ? ? 36.91 42.83 3 1 ALA B 299 ? ? -82.37 36.11 4 1 ASN C 5 ? ? -62.18 27.53 5 1 ASN C 75 ? ? -131.28 -70.22 6 1 ARG D 251 ? ? -107.52 -167.33 # _pdbx_validate_peptide_omega.id 1 _pdbx_validate_peptide_omega.PDB_model_num 1 _pdbx_validate_peptide_omega.auth_comp_id_1 GLY _pdbx_validate_peptide_omega.auth_asym_id_1 C _pdbx_validate_peptide_omega.auth_seq_id_1 4 _pdbx_validate_peptide_omega.PDB_ins_code_1 ? _pdbx_validate_peptide_omega.label_alt_id_1 ? _pdbx_validate_peptide_omega.auth_comp_id_2 ASN _pdbx_validate_peptide_omega.auth_asym_id_2 C _pdbx_validate_peptide_omega.auth_seq_id_2 5 _pdbx_validate_peptide_omega.PDB_ins_code_2 ? _pdbx_validate_peptide_omega.label_alt_id_2 ? _pdbx_validate_peptide_omega.omega 72.30 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A LEU 1 ? A LEU 1 2 1 Y 1 A THR 2 ? A THR 2 3 1 Y 1 A LEU 3 ? A LEU 3 4 1 Y 1 A SER 166 ? A SER 166 5 1 Y 1 B HIS 342 ? B HIS 172 6 1 Y 1 B HIS 343 ? B HIS 173 7 1 Y 1 B HIS 344 ? B HIS 174 8 1 Y 1 B HIS 345 ? B HIS 175 9 1 Y 1 B HIS 346 ? B HIS 176 10 1 Y 1 C SER 166 ? C SER 166 11 1 Y 1 D HIS 342 ? D HIS 172 12 1 Y 1 D HIS 343 ? D HIS 173 13 1 Y 1 D HIS 344 ? D HIS 174 14 1 Y 1 D HIS 345 ? D HIS 175 15 1 Y 1 D HIS 346 ? D HIS 176 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 3 N-ACETYL-D-GLUCOSAMINE NAG 4 ;(3R,4S)-N-{2-chloro-5-[(cyclopropylamino)methyl]benzyl}-N-cyclopropyl-4-{6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]pyridin-3-yl}piperidine-3-carboxamide ; LPQ 5 water HOH # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code E 3 NAG 1 166 2 NAG NAG A . F 4 LPQ 1 167 1 LPQ LPQ A . G 3 NAG 1 166 2 NAG NAG C . H 4 LPQ 1 167 1 LPQ LPQ C . I 5 HOH 1 168 2 HOH HOH A . I 5 HOH 2 169 3 HOH HOH A . I 5 HOH 3 170 170 HOH HOH A . I 5 HOH 4 171 171 HOH HOH A . I 5 HOH 5 172 6 HOH HOH A . I 5 HOH 6 173 173 HOH HOH A . I 5 HOH 7 174 174 HOH HOH A . I 5 HOH 8 175 175 HOH HOH A . I 5 HOH 9 176 7 HOH HOH A . I 5 HOH 10 177 8 HOH HOH A . I 5 HOH 11 178 10 HOH HOH A . I 5 HOH 12 179 179 HOH HOH A . I 5 HOH 13 180 11 HOH HOH A . I 5 HOH 14 181 12 HOH HOH A . I 5 HOH 15 182 15 HOH HOH A . I 5 HOH 16 183 183 HOH HOH A . I 5 HOH 17 184 21 HOH HOH A . I 5 HOH 18 185 23 HOH HOH A . I 5 HOH 19 186 24 HOH HOH A . I 5 HOH 20 187 187 HOH HOH A . I 5 HOH 21 188 30 HOH HOH A . I 5 HOH 22 189 31 HOH HOH A . I 5 HOH 23 190 32 HOH HOH A . I 5 HOH 24 191 36 HOH HOH A . I 5 HOH 25 192 39 HOH HOH A . I 5 HOH 26 193 41 HOH HOH A . I 5 HOH 27 194 42 HOH HOH A . I 5 HOH 28 195 195 HOH HOH A . I 5 HOH 29 196 49 HOH HOH A . I 5 HOH 30 197 54 HOH HOH A . I 5 HOH 31 198 61 HOH HOH A . I 5 HOH 32 199 62 HOH HOH A . I 5 HOH 33 200 64 HOH HOH A . I 5 HOH 34 201 70 HOH HOH A . I 5 HOH 35 202 71 HOH HOH A . I 5 HOH 36 203 73 HOH HOH A . I 5 HOH 37 204 80 HOH HOH A . I 5 HOH 38 205 84 HOH HOH A . I 5 HOH 39 206 85 HOH HOH A . I 5 HOH 40 207 90 HOH HOH A . I 5 HOH 41 208 95 HOH HOH A . I 5 HOH 42 209 96 HOH HOH A . I 5 HOH 43 210 98 HOH HOH A . I 5 HOH 44 211 99 HOH HOH A . I 5 HOH 45 212 100 HOH HOH A . I 5 HOH 46 213 103 HOH HOH A . I 5 HOH 47 214 112 HOH HOH A . I 5 HOH 48 215 117 HOH HOH A . I 5 HOH 49 216 129 HOH HOH A . I 5 HOH 50 217 133 HOH HOH A . I 5 HOH 51 218 140 HOH HOH A . I 5 HOH 52 219 155 HOH HOH A . I 5 HOH 53 220 160 HOH HOH A . I 5 HOH 54 221 162 HOH HOH A . I 5 HOH 55 222 163 HOH HOH A . J 5 HOH 1 9 9 HOH HOH B . J 5 HOH 2 13 13 HOH HOH B . J 5 HOH 3 22 22 HOH HOH B . J 5 HOH 4 25 25 HOH HOH B . J 5 HOH 5 28 28 HOH HOH B . J 5 HOH 6 29 29 HOH HOH B . J 5 HOH 7 33 33 HOH HOH B . J 5 HOH 8 34 34 HOH HOH B . J 5 HOH 9 35 35 HOH HOH B . J 5 HOH 10 38 38 HOH HOH B . J 5 HOH 11 51 51 HOH HOH B . J 5 HOH 12 52 52 HOH HOH B . J 5 HOH 13 57 57 HOH HOH B . J 5 HOH 14 58 58 HOH HOH B . J 5 HOH 15 60 60 HOH HOH B . J 5 HOH 16 66 66 HOH HOH B . J 5 HOH 17 75 75 HOH HOH B . J 5 HOH 18 79 79 HOH HOH B . J 5 HOH 19 81 81 HOH HOH B . J 5 HOH 20 82 82 HOH HOH B . J 5 HOH 21 87 87 HOH HOH B . J 5 HOH 22 91 91 HOH HOH B . J 5 HOH 23 92 92 HOH HOH B . J 5 HOH 24 102 102 HOH HOH B . J 5 HOH 25 104 104 HOH HOH B . J 5 HOH 26 109 109 HOH HOH B . J 5 HOH 27 110 110 HOH HOH B . J 5 HOH 28 123 123 HOH HOH B . J 5 HOH 29 124 124 HOH HOH B . J 5 HOH 30 135 135 HOH HOH B . J 5 HOH 31 138 138 HOH HOH B . J 5 HOH 32 152 152 HOH HOH B . J 5 HOH 33 156 156 HOH HOH B . J 5 HOH 34 157 157 HOH HOH B . J 5 HOH 35 158 158 HOH HOH B . J 5 HOH 36 161 161 HOH HOH B . J 5 HOH 37 169 169 HOH HOH B . J 5 HOH 38 347 176 HOH HOH B . J 5 HOH 39 348 178 HOH HOH B . J 5 HOH 40 349 182 HOH HOH B . J 5 HOH 41 350 186 HOH HOH B . J 5 HOH 42 351 189 HOH HOH B . J 5 HOH 43 352 192 HOH HOH B . K 5 HOH 1 168 168 HOH HOH C . K 5 HOH 2 169 4 HOH HOH C . K 5 HOH 3 170 17 HOH HOH C . K 5 HOH 4 171 19 HOH HOH C . K 5 HOH 5 172 172 HOH HOH C . K 5 HOH 6 173 26 HOH HOH C . K 5 HOH 7 174 27 HOH HOH C . K 5 HOH 8 175 37 HOH HOH C . K 5 HOH 9 176 40 HOH HOH C . K 5 HOH 10 177 46 HOH HOH C . K 5 HOH 11 178 47 HOH HOH C . K 5 HOH 12 179 50 HOH HOH C . K 5 HOH 13 180 180 HOH HOH C . K 5 HOH 14 181 53 HOH HOH C . K 5 HOH 15 182 55 HOH HOH C . K 5 HOH 16 183 59 HOH HOH C . K 5 HOH 17 184 67 HOH HOH C . K 5 HOH 18 185 72 HOH HOH C . K 5 HOH 19 186 86 HOH HOH C . K 5 HOH 20 187 89 HOH HOH C . K 5 HOH 21 188 93 HOH HOH C . K 5 HOH 22 189 97 HOH HOH C . K 5 HOH 23 190 105 HOH HOH C . K 5 HOH 24 191 106 HOH HOH C . K 5 HOH 25 192 107 HOH HOH C . K 5 HOH 26 193 108 HOH HOH C . K 5 HOH 27 194 113 HOH HOH C . K 5 HOH 28 195 118 HOH HOH C . K 5 HOH 29 196 196 HOH HOH C . K 5 HOH 30 197 120 HOH HOH C . K 5 HOH 31 198 121 HOH HOH C . K 5 HOH 32 199 127 HOH HOH C . K 5 HOH 33 200 130 HOH HOH C . K 5 HOH 34 201 139 HOH HOH C . K 5 HOH 35 202 141 HOH HOH C . K 5 HOH 36 203 144 HOH HOH C . K 5 HOH 37 204 146 HOH HOH C . K 5 HOH 38 205 147 HOH HOH C . K 5 HOH 39 206 148 HOH HOH C . K 5 HOH 40 207 150 HOH HOH C . K 5 HOH 41 208 151 HOH HOH C . K 5 HOH 42 209 153 HOH HOH C . K 5 HOH 43 210 159 HOH HOH C . K 5 HOH 44 211 165 HOH HOH C . K 5 HOH 45 212 166 HOH HOH C . L 5 HOH 1 1 1 HOH HOH D . L 5 HOH 2 14 14 HOH HOH D . L 5 HOH 3 16 16 HOH HOH D . L 5 HOH 4 18 18 HOH HOH D . L 5 HOH 5 20 20 HOH HOH D . L 5 HOH 6 43 43 HOH HOH D . L 5 HOH 7 44 44 HOH HOH D . L 5 HOH 8 48 48 HOH HOH D . L 5 HOH 9 63 63 HOH HOH D . L 5 HOH 10 65 65 HOH HOH D . L 5 HOH 11 68 68 HOH HOH D . L 5 HOH 12 69 69 HOH HOH D . L 5 HOH 13 76 76 HOH HOH D . L 5 HOH 14 78 78 HOH HOH D . L 5 HOH 15 83 83 HOH HOH D . L 5 HOH 16 88 88 HOH HOH D . L 5 HOH 17 94 94 HOH HOH D . L 5 HOH 18 101 101 HOH HOH D . L 5 HOH 19 111 111 HOH HOH D . L 5 HOH 20 114 114 HOH HOH D . L 5 HOH 21 115 115 HOH HOH D . L 5 HOH 22 116 116 HOH HOH D . L 5 HOH 23 119 119 HOH HOH D . L 5 HOH 24 122 122 HOH HOH D . L 5 HOH 25 125 125 HOH HOH D . L 5 HOH 26 126 126 HOH HOH D . L 5 HOH 27 128 128 HOH HOH D . L 5 HOH 28 131 131 HOH HOH D . L 5 HOH 29 132 132 HOH HOH D . L 5 HOH 30 136 136 HOH HOH D . L 5 HOH 31 137 137 HOH HOH D . L 5 HOH 32 142 142 HOH HOH D . L 5 HOH 33 149 149 HOH HOH D . L 5 HOH 34 154 154 HOH HOH D . L 5 HOH 35 347 185 HOH HOH D . L 5 HOH 36 348 188 HOH HOH D . L 5 HOH 37 349 193 HOH HOH D . #