data_3LQA # _entry.id 3LQA # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3LQA RCSB RCSB057595 WWPDB D_1000057595 # _pdbx_database_related.db_name PDB _pdbx_database_related.db_id 3LMJ _pdbx_database_related.details '21c Fab unbound' _pdbx_database_related.content_type unspecified # _pdbx_database_status.entry_id 3LQA _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2010-02-08 _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Diskin, R.' 1 'Marcovecchio, P.M.' 2 'Bjorkman, P.J.' 3 # _citation.id primary _citation.title 'Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity.' _citation.journal_abbrev Nat.Struct.Mol.Biol. _citation.journal_volume 17 _citation.page_first 608 _citation.page_last 613 _citation.year 2010 _citation.journal_id_ASTM ? _citation.country US _citation.journal_id_ISSN 1545-9993 _citation.journal_id_CSD ? _citation.book_publisher ? _citation.pdbx_database_id_PubMed 20357769 _citation.pdbx_database_id_DOI 10.1038/nsmb.1796 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Diskin, R.' 1 primary 'Marcovecchio, P.M.' 2 primary 'Bjorkman, P.J.' 3 # _cell.length_a 93.730 _cell.length_b 187.930 _cell.length_c 151.670 _cell.angle_alpha 90.000 _cell.angle_beta 90.000 _cell.angle_gamma 90.000 _cell.entry_id 3LQA _cell.pdbx_unique_axis ? _cell.Z_PDB 8 _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.space_group_name_H-M 'C 2 2 21' _symmetry.entry_id 3LQA _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.Int_Tables_number 20 _symmetry.cell_setting ? _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'T-cell surface glycoprotein CD4' 21472.350 1 ? ? ? ? 2 polymer man 'Envelope glycoprotein gp160' 36794.566 1 ? 'T89I, N226D, T232I, N285T, S329N, T388I, N447D' ? ? 3 polymer man 'Heavy chain of anti HIV Fab from human 21c antibody' 24619.590 1 ? ? ? ? 4 polymer man 'Light chain of anti HIV Fab from human 21c antibody' 22815.264 1 ? ? ? ? 5 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 4 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;KKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSD TYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCT VLQNQKKVEFKIDIVVLAFQKAIDGRHHHHHH ; ;KKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSD TYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCT VLQNQKKVEFKIDIVVLAFQKAIDGRHHHHHH ; C ? 2 'polypeptide(L)' no no ;EIVLENVIENFNMWKNDMVDQMHQDIISLWDQSLKPCVKLTPLCVGAGNCNTSTIAQACPKVSFDPIPIHYCAPAGYAIL KCNDKTFNGIGPCNNVSTVQCTHGIKPVVSTQLLLNGSLAEEEVVIRSENISNNVKTIIVHLTESVNITCIGAGHCNINE KAWNETLKKVVEKLVKYFPNKTIEFAPPVGGDLEITTHSFNCGGEFFYCNTTKLFNSIHNSTDSTVNSTDSTAETGNSTN TNITLPCRIRQIINMWQEVGRAMYAPPSKGNITCISDITGLLLTRDGGENKTENNDTEIFRPGGGDMKDNWRSELYKYKV VEIKSGHHHHHH ; ;EIVLENVIENFNMWKNDMVDQMHQDIISLWDQSLKPCVKLTPLCVGAGNCNTSTIAQACPKVSFDPIPIHYCAPAGYAIL KCNDKTFNGIGPCNNVSTVQCTHGIKPVVSTQLLLNGSLAEEEVVIRSENISNNVKTIIVHLTESVNITCIGAGHCNINE KAWNETLKKVVEKLVKYFPNKTIEFAPPVGGDLEITTHSFNCGGEFFYCNTTKLFNSIHNSTDSTVNSTDSTAETGNSTN TNITLPCRIRQIINMWQEVGRAMYAPPSKGNITCISDITGLLLTRDGGENKTENNDTEIFRPGGGDMKDNWRSELYKYKV VEIKSGHHHHHH ; G ? 3 'polypeptide(L)' no no ;QVQVVQSGAEVRKPGASVKVSCKVSGFTLTGLSIHWVRQAPGKGLEWMGGFGPEENEIIYAQKFQGRVSMTEDTSTNTAY MELSSLRSEDTAVYYCATGGNYYNLWTGYYPLAYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPE PVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKT ; ;QVQVVQSGAEVRKPGASVKVSCKVSGFTLTGLSIHWVRQAPGKGLEWMGGFGPEENEIIYAQKFQGRVSMTEDTSTNTAY MELSSLRSEDTAVYYCATGGNYYNLWTGYYPLAYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPE PVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKT ; H ? 4 'polypeptide(L)' no no ;QSVLTQPPSVSAAPGQKVTISCSGSSSNIGKNYVSWYQQLPGAAPKLLIFDDTQRPSGIPDRFSGSKSGTSATLAITGLQ TGDEADYYCGTWDSSLSTGQLFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPV KAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTMAHAECS ; ;QSVLTQPPSVSAAPGQKVTISCSGSSSNIGKNYVSWYQQLPGAAPKLLIFDDTQRPSGIPDRFSGSKSGTSATLAITGLQ TGDEADYYCGTWDSSLSTGQLFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPV KAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTMAHAECS ; L ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 LYS n 1 2 LYS n 1 3 VAL n 1 4 VAL n 1 5 LEU n 1 6 GLY n 1 7 LYS n 1 8 LYS n 1 9 GLY n 1 10 ASP n 1 11 THR n 1 12 VAL n 1 13 GLU n 1 14 LEU n 1 15 THR n 1 16 CYS n 1 17 THR n 1 18 ALA n 1 19 SER n 1 20 GLN n 1 21 LYS n 1 22 LYS n 1 23 SER n 1 24 ILE n 1 25 GLN n 1 26 PHE n 1 27 HIS n 1 28 TRP n 1 29 LYS n 1 30 ASN n 1 31 SER n 1 32 ASN n 1 33 GLN n 1 34 ILE n 1 35 LYS n 1 36 ILE n 1 37 LEU n 1 38 GLY n 1 39 ASN n 1 40 GLN n 1 41 GLY n 1 42 SER n 1 43 PHE n 1 44 LEU n 1 45 THR n 1 46 LYS n 1 47 GLY n 1 48 PRO n 1 49 SER n 1 50 LYS n 1 51 LEU n 1 52 ASN n 1 53 ASP n 1 54 ARG n 1 55 ALA n 1 56 ASP n 1 57 SER n 1 58 ARG n 1 59 ARG n 1 60 SER n 1 61 LEU n 1 62 TRP n 1 63 ASP n 1 64 GLN n 1 65 GLY n 1 66 ASN n 1 67 PHE n 1 68 PRO n 1 69 LEU n 1 70 ILE n 1 71 ILE n 1 72 LYS n 1 73 ASN n 1 74 LEU n 1 75 LYS n 1 76 ILE n 1 77 GLU n 1 78 ASP n 1 79 SER n 1 80 ASP n 1 81 THR n 1 82 TYR n 1 83 ILE n 1 84 CYS n 1 85 GLU n 1 86 VAL n 1 87 GLU n 1 88 ASP n 1 89 GLN n 1 90 LYS n 1 91 GLU n 1 92 GLU n 1 93 VAL n 1 94 GLN n 1 95 LEU n 1 96 LEU n 1 97 VAL n 1 98 PHE n 1 99 GLY n 1 100 LEU n 1 101 THR n 1 102 ALA n 1 103 ASN n 1 104 SER n 1 105 ASP n 1 106 THR n 1 107 HIS n 1 108 LEU n 1 109 LEU n 1 110 GLN n 1 111 GLY n 1 112 GLN n 1 113 SER n 1 114 LEU n 1 115 THR n 1 116 LEU n 1 117 THR n 1 118 LEU n 1 119 GLU n 1 120 SER n 1 121 PRO n 1 122 PRO n 1 123 GLY n 1 124 SER n 1 125 SER n 1 126 PRO n 1 127 SER n 1 128 VAL n 1 129 GLN n 1 130 CYS n 1 131 ARG n 1 132 SER n 1 133 PRO n 1 134 ARG n 1 135 GLY n 1 136 LYS n 1 137 ASN n 1 138 ILE n 1 139 GLN n 1 140 GLY n 1 141 GLY n 1 142 LYS n 1 143 THR n 1 144 LEU n 1 145 SER n 1 146 VAL n 1 147 SER n 1 148 GLN n 1 149 LEU n 1 150 GLU n 1 151 LEU n 1 152 GLN n 1 153 ASP n 1 154 SER n 1 155 GLY n 1 156 THR n 1 157 TRP n 1 158 THR n 1 159 CYS n 1 160 THR n 1 161 VAL n 1 162 LEU n 1 163 GLN n 1 164 ASN n 1 165 GLN n 1 166 LYS n 1 167 LYS n 1 168 VAL n 1 169 GLU n 1 170 PHE n 1 171 LYS n 1 172 ILE n 1 173 ASP n 1 174 ILE n 1 175 VAL n 1 176 VAL n 1 177 LEU n 1 178 ALA n 1 179 PHE n 1 180 GLN n 1 181 LYS n 1 182 ALA n 1 183 ILE n 1 184 ASP n 1 185 GLY n 1 186 ARG n 1 187 HIS n 1 188 HIS n 1 189 HIS n 1 190 HIS n 1 191 HIS n 1 192 HIS n 2 1 GLU n 2 2 ILE n 2 3 VAL n 2 4 LEU n 2 5 GLU n 2 6 ASN n 2 7 VAL n 2 8 ILE n 2 9 GLU n 2 10 ASN n 2 11 PHE n 2 12 ASN n 2 13 MET n 2 14 TRP n 2 15 LYS n 2 16 ASN n 2 17 ASP n 2 18 MET n 2 19 VAL n 2 20 ASP n 2 21 GLN n 2 22 MET n 2 23 HIS n 2 24 GLN n 2 25 ASP n 2 26 ILE n 2 27 ILE n 2 28 SER n 2 29 LEU n 2 30 TRP n 2 31 ASP n 2 32 GLN n 2 33 SER n 2 34 LEU n 2 35 LYS n 2 36 PRO n 2 37 CYS n 2 38 VAL n 2 39 LYS n 2 40 LEU n 2 41 THR n 2 42 PRO n 2 43 LEU n 2 44 CYS n 2 45 VAL n 2 46 GLY n 2 47 ALA n 2 48 GLY n 2 49 ASN n 2 50 CYS n 2 51 ASN n 2 52 THR n 2 53 SER n 2 54 THR n 2 55 ILE n 2 56 ALA n 2 57 GLN n 2 58 ALA n 2 59 CYS n 2 60 PRO n 2 61 LYS n 2 62 VAL n 2 63 SER n 2 64 PHE n 2 65 ASP n 2 66 PRO n 2 67 ILE n 2 68 PRO n 2 69 ILE n 2 70 HIS n 2 71 TYR n 2 72 CYS n 2 73 ALA n 2 74 PRO n 2 75 ALA n 2 76 GLY n 2 77 TYR n 2 78 ALA n 2 79 ILE n 2 80 LEU n 2 81 LYS n 2 82 CYS n 2 83 ASN n 2 84 ASP n 2 85 LYS n 2 86 THR n 2 87 PHE n 2 88 ASN n 2 89 GLY n 2 90 ILE n 2 91 GLY n 2 92 PRO n 2 93 CYS n 2 94 ASN n 2 95 ASN n 2 96 VAL n 2 97 SER n 2 98 THR n 2 99 VAL n 2 100 GLN n 2 101 CYS n 2 102 THR n 2 103 HIS n 2 104 GLY n 2 105 ILE n 2 106 LYS n 2 107 PRO n 2 108 VAL n 2 109 VAL n 2 110 SER n 2 111 THR n 2 112 GLN n 2 113 LEU n 2 114 LEU n 2 115 LEU n 2 116 ASN n 2 117 GLY n 2 118 SER n 2 119 LEU n 2 120 ALA n 2 121 GLU n 2 122 GLU n 2 123 GLU n 2 124 VAL n 2 125 VAL n 2 126 ILE n 2 127 ARG n 2 128 SER n 2 129 GLU n 2 130 ASN n 2 131 ILE n 2 132 SER n 2 133 ASN n 2 134 ASN n 2 135 VAL n 2 136 LYS n 2 137 THR n 2 138 ILE n 2 139 ILE n 2 140 VAL n 2 141 HIS n 2 142 LEU n 2 143 THR n 2 144 GLU n 2 145 SER n 2 146 VAL n 2 147 ASN n 2 148 ILE n 2 149 THR n 2 150 CYS n 2 151 ILE n 2 152 GLY n 2 153 ALA n 2 154 GLY n 2 155 HIS n 2 156 CYS n 2 157 ASN n 2 158 ILE n 2 159 ASN n 2 160 GLU n 2 161 LYS n 2 162 ALA n 2 163 TRP n 2 164 ASN n 2 165 GLU n 2 166 THR n 2 167 LEU n 2 168 LYS n 2 169 LYS n 2 170 VAL n 2 171 VAL n 2 172 GLU n 2 173 LYS n 2 174 LEU n 2 175 VAL n 2 176 LYS n 2 177 TYR n 2 178 PHE n 2 179 PRO n 2 180 ASN n 2 181 LYS n 2 182 THR n 2 183 ILE n 2 184 GLU n 2 185 PHE n 2 186 ALA n 2 187 PRO n 2 188 PRO n 2 189 VAL n 2 190 GLY n 2 191 GLY n 2 192 ASP n 2 193 LEU n 2 194 GLU n 2 195 ILE n 2 196 THR n 2 197 THR n 2 198 HIS n 2 199 SER n 2 200 PHE n 2 201 ASN n 2 202 CYS n 2 203 GLY n 2 204 GLY n 2 205 GLU n 2 206 PHE n 2 207 PHE n 2 208 TYR n 2 209 CYS n 2 210 ASN n 2 211 THR n 2 212 THR n 2 213 LYS n 2 214 LEU n 2 215 PHE n 2 216 ASN n 2 217 SER n 2 218 ILE n 2 219 HIS n 2 220 ASN n 2 221 SER n 2 222 THR n 2 223 ASP n 2 224 SER n 2 225 THR n 2 226 VAL n 2 227 ASN n 2 228 SER n 2 229 THR n 2 230 ASP n 2 231 SER n 2 232 THR n 2 233 ALA n 2 234 GLU n 2 235 THR n 2 236 GLY n 2 237 ASN n 2 238 SER n 2 239 THR n 2 240 ASN n 2 241 THR n 2 242 ASN n 2 243 ILE n 2 244 THR n 2 245 LEU n 2 246 PRO n 2 247 CYS n 2 248 ARG n 2 249 ILE n 2 250 ARG n 2 251 GLN n 2 252 ILE n 2 253 ILE n 2 254 ASN n 2 255 MET n 2 256 TRP n 2 257 GLN n 2 258 GLU n 2 259 VAL n 2 260 GLY n 2 261 ARG n 2 262 ALA n 2 263 MET n 2 264 TYR n 2 265 ALA n 2 266 PRO n 2 267 PRO n 2 268 SER n 2 269 LYS n 2 270 GLY n 2 271 ASN n 2 272 ILE n 2 273 THR n 2 274 CYS n 2 275 ILE n 2 276 SER n 2 277 ASP n 2 278 ILE n 2 279 THR n 2 280 GLY n 2 281 LEU n 2 282 LEU n 2 283 LEU n 2 284 THR n 2 285 ARG n 2 286 ASP n 2 287 GLY n 2 288 GLY n 2 289 GLU n 2 290 ASN n 2 291 LYS n 2 292 THR n 2 293 GLU n 2 294 ASN n 2 295 ASN n 2 296 ASP n 2 297 THR n 2 298 GLU n 2 299 ILE n 2 300 PHE n 2 301 ARG n 2 302 PRO n 2 303 GLY n 2 304 GLY n 2 305 GLY n 2 306 ASP n 2 307 MET n 2 308 LYS n 2 309 ASP n 2 310 ASN n 2 311 TRP n 2 312 ARG n 2 313 SER n 2 314 GLU n 2 315 LEU n 2 316 TYR n 2 317 LYS n 2 318 TYR n 2 319 LYS n 2 320 VAL n 2 321 VAL n 2 322 GLU n 2 323 ILE n 2 324 LYS n 2 325 SER n 2 326 GLY n 2 327 HIS n 2 328 HIS n 2 329 HIS n 2 330 HIS n 2 331 HIS n 2 332 HIS n 3 1 GLN n 3 2 VAL n 3 3 GLN n 3 4 VAL n 3 5 VAL n 3 6 GLN n 3 7 SER n 3 8 GLY n 3 9 ALA n 3 10 GLU n 3 11 VAL n 3 12 ARG n 3 13 LYS n 3 14 PRO n 3 15 GLY n 3 16 ALA n 3 17 SER n 3 18 VAL n 3 19 LYS n 3 20 VAL n 3 21 SER n 3 22 CYS n 3 23 LYS n 3 24 VAL n 3 25 SER n 3 26 GLY n 3 27 PHE n 3 28 THR n 3 29 LEU n 3 30 THR n 3 31 GLY n 3 32 LEU n 3 33 SER n 3 34 ILE n 3 35 HIS n 3 36 TRP n 3 37 VAL n 3 38 ARG n 3 39 GLN n 3 40 ALA n 3 41 PRO n 3 42 GLY n 3 43 LYS n 3 44 GLY n 3 45 LEU n 3 46 GLU n 3 47 TRP n 3 48 MET n 3 49 GLY n 3 50 GLY n 3 51 PHE n 3 52 GLY n 3 53 PRO n 3 54 GLU n 3 55 GLU n 3 56 ASN n 3 57 GLU n 3 58 ILE n 3 59 ILE n 3 60 TYR n 3 61 ALA n 3 62 GLN n 3 63 LYS n 3 64 PHE n 3 65 GLN n 3 66 GLY n 3 67 ARG n 3 68 VAL n 3 69 SER n 3 70 MET n 3 71 THR n 3 72 GLU n 3 73 ASP n 3 74 THR n 3 75 SER n 3 76 THR n 3 77 ASN n 3 78 THR n 3 79 ALA n 3 80 TYR n 3 81 MET n 3 82 GLU n 3 83 LEU n 3 84 SER n 3 85 SER n 3 86 LEU n 3 87 ARG n 3 88 SER n 3 89 GLU n 3 90 ASP n 3 91 THR n 3 92 ALA n 3 93 VAL n 3 94 TYR n 3 95 TYR n 3 96 CYS n 3 97 ALA n 3 98 THR n 3 99 GLY n 3 100 GLY n 3 101 ASN n 3 102 TYR n 3 103 TYR n 3 104 ASN n 3 105 LEU n 3 106 TRP n 3 107 THR n 3 108 GLY n 3 109 TYR n 3 110 TYR n 3 111 PRO n 3 112 LEU n 3 113 ALA n 3 114 TYR n 3 115 TRP n 3 116 GLY n 3 117 GLN n 3 118 GLY n 3 119 THR n 3 120 LEU n 3 121 VAL n 3 122 THR n 3 123 VAL n 3 124 SER n 3 125 SER n 3 126 ALA n 3 127 SER n 3 128 THR n 3 129 LYS n 3 130 GLY n 3 131 PRO n 3 132 SER n 3 133 VAL n 3 134 PHE n 3 135 PRO n 3 136 LEU n 3 137 ALA n 3 138 PRO n 3 139 SER n 3 140 SER n 3 141 LYS n 3 142 SER n 3 143 THR n 3 144 SER n 3 145 GLY n 3 146 GLY n 3 147 THR n 3 148 ALA n 3 149 ALA n 3 150 LEU n 3 151 GLY n 3 152 CYS n 3 153 LEU n 3 154 VAL n 3 155 LYS n 3 156 ASP n 3 157 TYR n 3 158 PHE n 3 159 PRO n 3 160 GLU n 3 161 PRO n 3 162 VAL n 3 163 THR n 3 164 VAL n 3 165 SER n 3 166 TRP n 3 167 ASN n 3 168 SER n 3 169 GLY n 3 170 ALA n 3 171 LEU n 3 172 THR n 3 173 SER n 3 174 GLY n 3 175 VAL n 3 176 HIS n 3 177 THR n 3 178 PHE n 3 179 PRO n 3 180 ALA n 3 181 VAL n 3 182 LEU n 3 183 GLN n 3 184 SER n 3 185 SER n 3 186 GLY n 3 187 LEU n 3 188 TYR n 3 189 SER n 3 190 LEU n 3 191 SER n 3 192 SER n 3 193 VAL n 3 194 VAL n 3 195 THR n 3 196 VAL n 3 197 PRO n 3 198 SER n 3 199 SER n 3 200 SER n 3 201 LEU n 3 202 GLY n 3 203 THR n 3 204 GLN n 3 205 THR n 3 206 TYR n 3 207 ILE n 3 208 CYS n 3 209 ASN n 3 210 VAL n 3 211 ASN n 3 212 HIS n 3 213 LYS n 3 214 PRO n 3 215 SER n 3 216 ASN n 3 217 THR n 3 218 LYS n 3 219 VAL n 3 220 ASP n 3 221 LYS n 3 222 LYS n 3 223 VAL n 3 224 GLU n 3 225 PRO n 3 226 LYS n 3 227 SER n 3 228 CYS n 3 229 ASP n 3 230 LYS n 3 231 THR n 4 1 GLN n 4 2 SER n 4 3 VAL n 4 4 LEU n 4 5 THR n 4 6 GLN n 4 7 PRO n 4 8 PRO n 4 9 SER n 4 10 VAL n 4 11 SER n 4 12 ALA n 4 13 ALA n 4 14 PRO n 4 15 GLY n 4 16 GLN n 4 17 LYS n 4 18 VAL n 4 19 THR n 4 20 ILE n 4 21 SER n 4 22 CYS n 4 23 SER n 4 24 GLY n 4 25 SER n 4 26 SER n 4 27 SER n 4 28 ASN n 4 29 ILE n 4 30 GLY n 4 31 LYS n 4 32 ASN n 4 33 TYR n 4 34 VAL n 4 35 SER n 4 36 TRP n 4 37 TYR n 4 38 GLN n 4 39 GLN n 4 40 LEU n 4 41 PRO n 4 42 GLY n 4 43 ALA n 4 44 ALA n 4 45 PRO n 4 46 LYS n 4 47 LEU n 4 48 LEU n 4 49 ILE n 4 50 PHE n 4 51 ASP n 4 52 ASP n 4 53 THR n 4 54 GLN n 4 55 ARG n 4 56 PRO n 4 57 SER n 4 58 GLY n 4 59 ILE n 4 60 PRO n 4 61 ASP n 4 62 ARG n 4 63 PHE n 4 64 SER n 4 65 GLY n 4 66 SER n 4 67 LYS n 4 68 SER n 4 69 GLY n 4 70 THR n 4 71 SER n 4 72 ALA n 4 73 THR n 4 74 LEU n 4 75 ALA n 4 76 ILE n 4 77 THR n 4 78 GLY n 4 79 LEU n 4 80 GLN n 4 81 THR n 4 82 GLY n 4 83 ASP n 4 84 GLU n 4 85 ALA n 4 86 ASP n 4 87 TYR n 4 88 TYR n 4 89 CYS n 4 90 GLY n 4 91 THR n 4 92 TRP n 4 93 ASP n 4 94 SER n 4 95 SER n 4 96 LEU n 4 97 SER n 4 98 THR n 4 99 GLY n 4 100 GLN n 4 101 LEU n 4 102 PHE n 4 103 GLY n 4 104 GLY n 4 105 GLY n 4 106 THR n 4 107 LYS n 4 108 LEU n 4 109 THR n 4 110 VAL n 4 111 LEU n 4 112 GLY n 4 113 GLN n 4 114 PRO n 4 115 LYS n 4 116 ALA n 4 117 ALA n 4 118 PRO n 4 119 SER n 4 120 VAL n 4 121 THR n 4 122 LEU n 4 123 PHE n 4 124 PRO n 4 125 PRO n 4 126 SER n 4 127 SER n 4 128 GLU n 4 129 GLU n 4 130 LEU n 4 131 GLN n 4 132 ALA n 4 133 ASN n 4 134 LYS n 4 135 ALA n 4 136 THR n 4 137 LEU n 4 138 VAL n 4 139 CYS n 4 140 LEU n 4 141 ILE n 4 142 SER n 4 143 ASP n 4 144 PHE n 4 145 TYR n 4 146 PRO n 4 147 GLY n 4 148 ALA n 4 149 VAL n 4 150 THR n 4 151 VAL n 4 152 ALA n 4 153 TRP n 4 154 LYS n 4 155 ALA n 4 156 ASP n 4 157 SER n 4 158 SER n 4 159 PRO n 4 160 VAL n 4 161 LYS n 4 162 ALA n 4 163 GLY n 4 164 VAL n 4 165 GLU n 4 166 THR n 4 167 THR n 4 168 THR n 4 169 PRO n 4 170 SER n 4 171 LYS n 4 172 GLN n 4 173 SER n 4 174 ASN n 4 175 ASN n 4 176 LYS n 4 177 TYR n 4 178 ALA n 4 179 ALA n 4 180 SER n 4 181 SER n 4 182 TYR n 4 183 LEU n 4 184 SER n 4 185 LEU n 4 186 THR n 4 187 PRO n 4 188 GLU n 4 189 GLN n 4 190 TRP n 4 191 LYS n 4 192 SER n 4 193 HIS n 4 194 ARG n 4 195 SER n 4 196 TYR n 4 197 SER n 4 198 CYS n 4 199 GLN n 4 200 VAL n 4 201 THR n 4 202 HIS n 4 203 GLU n 4 204 GLY n 4 205 SER n 4 206 THR n 4 207 VAL n 4 208 GLU n 4 209 LYS n 4 210 THR n 4 211 MET n 4 212 ALA n 4 213 HIS n 4 214 ALA n 4 215 GLU n 4 216 CYS n 4 217 SER n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample ? ? ? ? ? CD4 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? Hi5 ? ? ? ? ? ? ? ? ? ? ? pACgp67b ? ? 2 1 sample ? 1 151 ? ? env ? ? ? ? ? ? HIV-1 11676 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? Hi5 ? ? ? ? ? ? ? ? ? ? ? pACgp67b ? ? 2 2 sample ? 155 324 ? ? env ? ? ? ? ? ? HIV-1 11676 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? Hi5 ? ? ? ? ? ? ? ? ? ? ? pACgp67b ? ? 3 1 sample ? ? ? ? ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 4 1 sample ? ? ? ? ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin _struct_ref.pdbx_db_isoform 1 UNP CD4_HUMAN P01730 1 ;KKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSD TYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCT VLQNQKKVEFKIDIVVLAFQKA ; 26 ? 2 UNP Q1PHM6_9HIV1 Q1PHM6 2 ;EIVLENVIENFNMWKNDMVDQMHQDIISLWDQSLKPCVKLTPLCVGAGNCNTSTIAQACPKVSFDPIPIHYCAPAGYAIL KCNDKTFNGIGPCNNVSTVQCTHGIKPVVSTQLLLNGSLAEEEVVIRSENISNNVKTIIVHLTESVNITCI ; 82 ? 3 UNP Q1PHM6_9HIV1 Q1PHM6 2 ;HCNISEKAWNETLKKVVEKLVKYFPNKTIEFAPPVGGDLEITTHSFNCGGEFFYCNTTKLFNSTHNSTDSTVNSTDSTAE TGNSTNTNITLPCRIRQIINMWQEVGRAMYAPPSKGNITCISNITGLLLTRDGGENKTENNDTEIFRPGGGDMKDNWRSE LYKYKVVEIK ; 325 ? 4 PDB 3LQA 3LQA 3 ;QVQVVQSGAEVRKPGASVKVSCKVSGFTLTGLSIHWVRQAPGKGLEWMGGFGPEENEIIYAQKFQGRVSMTEDTSTNTAY MELSSLRSEDTAVYYCATGGNYYNLWTGYYPLAYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPE PVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKT ; ? ? 5 PDB 3LQA 3LQA 4 ;QSVLTQPPSVSAAPGQKVTISCSGSSSNIGKNYVSWYQQLPGAAPKLLIFDDTQRPSGIPDRFSGSKSGTSATLAITGLQ TGDEADYYCGTWDSSLSTGQLFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPV KAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTMAHAECS ; ? ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 3LQA C 1 ? 182 ? P01730 26 ? 207 ? 1 182 2 2 3LQA G 1 ? 151 ? Q1PHM6 82 ? 232 ? 82 293 3 3 3LQA G 155 ? 324 ? Q1PHM6 325 ? 494 ? 325 494 4 4 3LQA H 1 ? 231 ? 3LQA 1 ? 231 ? 1 231 5 5 3LQA L 1 ? 217 ? 3LQA 2 ? 218 ? 2 218 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3LQA ILE C 183 ? UNP P01730 ? ? 'EXPRESSION TAG' 183 1 1 3LQA ASP C 184 ? UNP P01730 ? ? 'EXPRESSION TAG' 184 2 1 3LQA GLY C 185 ? UNP P01730 ? ? 'EXPRESSION TAG' 185 3 1 3LQA ARG C 186 ? UNP P01730 ? ? 'EXPRESSION TAG' 186 4 1 3LQA HIS C 187 ? UNP P01730 ? ? 'EXPRESSION TAG' 187 5 1 3LQA HIS C 188 ? UNP P01730 ? ? 'EXPRESSION TAG' 188 6 1 3LQA HIS C 189 ? UNP P01730 ? ? 'EXPRESSION TAG' 189 7 1 3LQA HIS C 190 ? UNP P01730 ? ? 'EXPRESSION TAG' 190 8 1 3LQA HIS C 191 ? UNP P01730 ? ? 'EXPRESSION TAG' 191 9 1 3LQA HIS C 192 ? UNP P01730 ? ? 'EXPRESSION TAG' 192 10 2 3LQA GLY G 152 ? UNP Q1PHM6 ? ? LINKER 294 11 2 3LQA ALA G 153 ? UNP Q1PHM6 ? ? LINKER 323 12 2 3LQA GLY G 154 ? UNP Q1PHM6 ? ? LINKER 324 13 2 3LQA ILE G 8 ? UNP Q1PHM6 THR 89 ENGINEERED 89 14 2 3LQA ASP G 84 ? UNP Q1PHM6 ASN 226 ENGINEERED 226 15 2 3LQA ILE G 90 ? UNP Q1PHM6 THR 232 ENGINEERED 232 16 2 3LQA THR G 143 ? UNP Q1PHM6 ASN 285 ENGINEERED 285 17 3 3LQA ASN G 159 ? UNP Q1PHM6 SER 329 ENGINEERED 329 18 3 3LQA ILE G 218 ? UNP Q1PHM6 THR 388 ENGINEERED 388 19 3 3LQA ASP G 277 ? UNP Q1PHM6 ASN 447 ENGINEERED 447 20 3 3LQA SER G 325 ? UNP Q1PHM6 ? ? 'EXPRESSION TAG' 495 21 3 3LQA GLY G 326 ? UNP Q1PHM6 ? ? 'EXPRESSION TAG' 496 22 3 3LQA HIS G 327 ? UNP Q1PHM6 ? ? 'EXPRESSION TAG' 497 23 3 3LQA HIS G 328 ? UNP Q1PHM6 ? ? 'EXPRESSION TAG' 498 24 3 3LQA HIS G 329 ? UNP Q1PHM6 ? ? 'EXPRESSION TAG' 499 25 3 3LQA HIS G 330 ? UNP Q1PHM6 ? ? 'EXPRESSION TAG' 500 26 3 3LQA HIS G 331 ? UNP Q1PHM6 ? ? 'EXPRESSION TAG' 501 27 3 3LQA HIS G 332 ? UNP Q1PHM6 ? ? 'EXPRESSION TAG' 502 28 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.crystals_number 1 _exptl.entry_id 3LQA _exptl.method 'X-RAY DIFFRACTION' # _exptl_crystal.id 1 _exptl_crystal.density_Matthews 3.16 _exptl_crystal.density_meas ? _exptl_crystal.density_percent_sol 61.07 _exptl_crystal.description ;The diffraction pattern from the crystals was very anisotropic. There is 80% completeness to 3.4A because the crystals diffracted to only 3.9A in the 'b' direction. ; _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.pH 8.5 _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_details ;20% (w/v) PEG monomethyl ether 2000, 5% (v/v) PEG 200, 0.2 M Trimethylamine N-oxide, 0.1 M Tris-HCl pH 8.5 , VAPOR DIFFUSION, SITTING DROP, temperature 293K ; _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'MARMOSAIC 325 mm CCD' _diffrn_detector.pdbx_collection_date 2009-06-23 _diffrn_detector.details 'Flat mirror, double crystal monochromator, vertical and horizontal focussing mirrors' # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator 'Liquid nitrogen-cooled double crystal' _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.953 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'SSRL BEAMLINE BL12-2' _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.953 _diffrn_source.pdbx_synchrotron_site SSRL _diffrn_source.pdbx_synchrotron_beamline BL12-2 # _reflns.entry_id 3LQA _reflns.observed_criterion_sigma_F 1 _reflns.observed_criterion_sigma_I 1 _reflns.d_resolution_high 3.4 _reflns.d_resolution_low 84.0 _reflns.number_all ? _reflns.number_obs 14975 _reflns.percent_possible_obs 79 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value 0.12 _reflns.pdbx_netI_over_sigmaI ? _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 3.5 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 # _reflns_shell.d_res_high 3.4 _reflns_shell.d_res_low 3.58 _reflns_shell.percent_possible_obs ? _reflns_shell.percent_possible_all ? _reflns_shell.Rmerge_I_obs ? _reflns_shell.meanI_over_sigI_obs 1.9 _reflns_shell.pdbx_Rsym_value 0.705 _reflns_shell.pdbx_redundancy ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_diffrn_id ? _reflns_shell.pdbx_ordinal 1 # _refine.entry_id 3LQA _refine.ls_d_res_high 3.400 _refine.ls_d_res_low 84.000 _refine.pdbx_ls_sigma_F 0.00 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_percent_reflns_obs 79.600 _refine.ls_number_reflns_obs 14967 _refine.ls_number_reflns_all ? _refine.pdbx_ls_cross_valid_method ? _refine.pdbx_R_Free_selection_details ;Random 5%, reduced to 0.5% for final rounds of refinement. R values were recorded before the final refinement rounds. ; _refine.details ? _refine.ls_R_factor_all ? _refine.ls_R_factor_obs ? _refine.ls_R_factor_R_work 0.234 _refine.ls_wR_factor_R_work ? _refine.ls_R_factor_R_free 0.322 _refine.ls_wR_factor_R_free ? _refine.ls_percent_reflns_R_free 40 _refine.ls_number_reflns_R_free 83 _refine.ls_R_factor_R_free_error ? _refine.B_iso_mean 101.992 _refine.solvent_model_param_bsol 75.543 _refine.solvent_model_param_ksol ? _refine.pdbx_isotropic_thermal_model Group _refine.aniso_B[1][1] -0.420 _refine.aniso_B[2][2] -1.107 _refine.aniso_B[3][3] 1.527 _refine.aniso_B[1][2] 0.000 _refine.aniso_B[1][3] 0.000 _refine.aniso_B[2][3] 0.000 _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.solvent_model_details ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_stereochem_target_val_spec_case ? _refine.overall_FOM_work_R_set ? _refine.B_iso_max 285.47 _refine.B_iso_min 12.02 _refine.occupancy_max 1.00 _refine.occupancy_min 1.00 _refine.pdbx_ls_sigma_I ? _refine.ls_redundancy_reflns_obs ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.overall_FOM_free_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_overall_ESU_R ? _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6889 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 56 _refine_hist.number_atoms_solvent 0 _refine_hist.number_atoms_total 6945 _refine_hist.d_res_high 3.400 _refine_hist.d_res_low 84.000 # loop_ _refine_ls_restr.type _refine_ls_restr.number _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d ? 0.024 ? ? 'X-RAY DIFFRACTION' ? c_angle_d ? 3.475 ? ? 'X-RAY DIFFRACTION' ? # loop_ _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file _pdbx_xplor_file.pdbx_refine_id 1 CNS_TOPPAR:protein_rep.param CNS_TOPPAR:protein.top 'X-RAY DIFFRACTION' 2 CNS_TOPPAR:dna-rna_rep.param CNS_TOPPAR:dna-rna.top 'X-RAY DIFFRACTION' 3 CNS_TOPPAR:water_rep.param CNS_TOPPAR:water.top 'X-RAY DIFFRACTION' 4 CNS_TOPPAR:ion.param CNS_TOPPAR:ion.top 'X-RAY DIFFRACTION' 5 CNS_TOPPAR:carbohydrate.param CNS_TOPPAR:carbohydrate.top 'X-RAY DIFFRACTION' # _struct.entry_id 3LQA _struct.title 'Crystal structure of clade C gp120 in complex with sCD4 and 21c Fab' _struct.pdbx_descriptor ;T-cell surface glycoprotein CD4, Envelope glycoprotein gp160, Heavy chain of anti HIV Fab from human 21c antibody, Light chain of anti HIV Fab from human 21c antibody ; _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3LQA _struct_keywords.pdbx_keywords 'IMMUNE SYSTEM' _struct_keywords.text 'complex, poly reactivity, IMMUNE SYSTEM' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 5 ? G N N 5 ? H N N 5 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 ARG A 59 ? ASP A 63 ? ARG C 59 ASP C 63 5 ? 5 HELX_P HELX_P2 2 ASN B 16 ? LEU B 34 ? ASN G 97 LEU G 115 1 ? 19 HELX_P HELX_P3 3 ASN B 159 ? PHE B 178 ? ASN G 329 PHE G 348 1 ? 20 HELX_P HELX_P4 4 ASP B 192 ? THR B 197 ? ASP G 362 THR G 367 1 ? 6 HELX_P HELX_P5 5 ASP B 306 ? TYR B 316 ? ASP G 476 TYR G 486 1 ? 11 HELX_P HELX_P6 6 GLN C 62 ? GLN C 65 ? GLN H 62 GLN H 65 5 ? 4 HELX_P HELX_P7 7 SER C 168 ? ALA C 170 ? SER H 168 ALA H 170 5 ? 3 HELX_P HELX_P8 8 SER C 198 ? GLN C 204 ? SER H 198 GLN H 204 1 ? 7 HELX_P HELX_P9 9 SER D 126 ? ALA D 132 ? SER L 127 ALA L 133 1 ? 7 HELX_P HELX_P10 10 THR D 186 ? HIS D 193 ? THR L 187 HIS L 194 1 ? 8 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 16 SG ? ? ? 1_555 A CYS 84 SG ? ? C CYS 16 C CYS 84 1_555 ? ? ? ? ? ? ? 2.014 ? disulf2 disulf ? ? A CYS 130 SG ? ? ? 1_555 A CYS 159 SG ? ? C CYS 130 C CYS 159 1_555 ? ? ? ? ? ? ? 2.046 ? disulf3 disulf ? ? B CYS 37 SG ? ? ? 1_555 B CYS 59 SG ? ? G CYS 118 G CYS 201 1_555 ? ? ? ? ? ? ? 2.042 ? disulf4 disulf ? ? B CYS 72 SG ? ? ? 1_555 B CYS 101 SG ? ? G CYS 214 G CYS 243 1_555 ? ? ? ? ? ? ? 2.025 ? disulf5 disulf ? ? B CYS 82 SG ? ? ? 1_555 B CYS 93 SG ? ? G CYS 224 G CYS 235 1_555 ? ? ? ? ? ? ? 2.046 ? disulf6 disulf ? ? B CYS 150 SG ? ? ? 1_555 B CYS 156 SG ? ? G CYS 292 G CYS 326 1_555 ? ? ? ? ? ? ? 2.015 ? disulf7 disulf ? ? B CYS 202 SG ? ? ? 1_555 B CYS 274 SG ? ? G CYS 372 G CYS 444 1_555 ? ? ? ? ? ? ? 2.033 ? disulf8 disulf ? ? B CYS 209 SG ? ? ? 1_555 B CYS 247 SG ? ? G CYS 379 G CYS 417 1_555 ? ? ? ? ? ? ? 2.032 ? disulf9 disulf ? ? C CYS 22 SG ? ? ? 1_555 C CYS 96 SG ? ? H CYS 22 H CYS 96 1_555 ? ? ? ? ? ? ? 2.060 ? disulf10 disulf ? ? C CYS 152 SG ? ? ? 1_555 C CYS 208 SG ? ? H CYS 152 H CYS 208 1_555 ? ? ? ? ? ? ? 2.014 ? disulf11 disulf ? ? D CYS 22 SG ? ? ? 1_555 D CYS 89 SG ? ? L CYS 23 L CYS 90 1_555 ? ? ? ? ? ? ? 2.042 ? disulf12 disulf ? ? D CYS 139 SG ? ? ? 1_555 D CYS 198 SG ? ? L CYS 140 L CYS 199 1_555 ? ? ? ? ? ? ? 2.016 ? covale1 covale ? ? B ASN 130 ND2 ? ? ? 1_555 F NAG . C1 ? ? G ASN 272 G NAG 1500 1_555 ? ? ? ? ? ? ? 1.522 ? covale2 covale ? ? B ASN 210 ND2 ? ? ? 1_555 G NAG . C1 ? ? G ASN 380 G NAG 2000 1_555 ? ? ? ? ? ? ? 1.526 ? covale3 covale ? ? B ASN 271 ND2 ? ? ? 1_555 H NAG . C1 ? ? G ASN 441 G NAG 2500 1_555 ? ? ? ? ? ? ? 1.560 ? covale4 covale ? ? B ASN 116 ND2 ? ? ? 1_555 E NAG . C1 ? ? G ASN 258 G NAG 1000 1_555 ? ? ? ? ? ? ? 1.567 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # _struct_mon_prot_cis.pdbx_id 1 _struct_mon_prot_cis.label_comp_id TYR _struct_mon_prot_cis.label_seq_id 145 _struct_mon_prot_cis.label_asym_id D _struct_mon_prot_cis.label_alt_id . _struct_mon_prot_cis.pdbx_PDB_ins_code ? _struct_mon_prot_cis.auth_comp_id TYR _struct_mon_prot_cis.auth_seq_id 146 _struct_mon_prot_cis.auth_asym_id L _struct_mon_prot_cis.pdbx_label_comp_id_2 PRO _struct_mon_prot_cis.pdbx_label_seq_id_2 146 _struct_mon_prot_cis.pdbx_label_asym_id_2 D _struct_mon_prot_cis.pdbx_PDB_ins_code_2 ? _struct_mon_prot_cis.pdbx_auth_comp_id_2 PRO _struct_mon_prot_cis.pdbx_auth_seq_id_2 147 _struct_mon_prot_cis.pdbx_auth_asym_id_2 L _struct_mon_prot_cis.pdbx_PDB_model_num 1 _struct_mon_prot_cis.pdbx_omega_angle -0.17 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 6 ? B ? 4 ? C ? 3 ? D ? 4 ? E ? 2 ? F ? 4 ? G ? 3 ? H ? 5 ? I ? 4 ? J ? 3 ? K ? 2 ? L ? 6 ? M ? 4 ? N ? 3 ? O ? 4 ? P ? 4 ? Q ? 3 ? R ? 5 ? S ? 4 ? T ? 3 ? U ? 4 ? V ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel A 4 5 ? anti-parallel A 5 6 ? anti-parallel B 1 2 ? parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel E 1 2 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel G 1 2 ? anti-parallel G 2 3 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? parallel I 3 4 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel K 1 2 ? anti-parallel L 1 2 ? parallel L 2 3 ? anti-parallel L 3 4 ? anti-parallel L 4 5 ? anti-parallel L 5 6 ? anti-parallel M 1 2 ? parallel M 2 3 ? anti-parallel M 3 4 ? anti-parallel N 1 2 ? anti-parallel N 2 3 ? anti-parallel O 1 2 ? anti-parallel O 2 3 ? anti-parallel O 3 4 ? anti-parallel P 1 2 ? anti-parallel P 2 3 ? anti-parallel P 3 4 ? anti-parallel Q 1 2 ? anti-parallel Q 2 3 ? anti-parallel R 1 2 ? parallel R 2 3 ? anti-parallel R 3 4 ? anti-parallel R 4 5 ? anti-parallel S 1 2 ? parallel S 2 3 ? anti-parallel S 3 4 ? anti-parallel T 1 2 ? anti-parallel T 2 3 ? anti-parallel U 1 2 ? anti-parallel U 2 3 ? anti-parallel U 3 4 ? anti-parallel V 1 2 ? anti-parallel V 2 3 ? anti-parallel V 3 4 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 VAL A 3 ? LYS A 7 ? VAL C 3 LYS C 7 A 2 GLN A 89 ? THR A 101 ? GLN C 89 THR C 101 A 3 ASP A 80 ? VAL A 86 ? ASP C 80 VAL C 86 A 4 PHE A 26 ? LYS A 29 ? PHE C 26 LYS C 29 A 5 LYS A 35 ? GLN A 40 ? LYS C 35 GLN C 40 A 6 PHE A 43 ? LYS A 46 ? PHE C 43 LYS C 46 B 1 VAL A 3 ? LYS A 7 ? VAL C 3 LYS C 7 B 2 GLN A 89 ? THR A 101 ? GLN C 89 THR C 101 B 3 LEU A 114 ? GLU A 119 ? LEU C 114 GLU C 119 B 4 THR A 143 ? VAL A 146 ? THR C 143 VAL C 146 C 1 VAL A 12 ? LEU A 14 ? VAL C 12 LEU C 14 C 2 LEU A 69 ? ILE A 71 ? LEU C 69 ILE C 71 C 3 ALA A 55 ? ASP A 56 ? ALA C 55 ASP C 56 D 1 ASN A 137 ? ILE A 138 ? ASN C 137 ILE C 138 D 2 VAL A 128 ? ARG A 131 ? VAL C 128 ARG C 131 D 3 TRP A 157 ? GLN A 163 ? TRP C 157 GLN C 163 D 4 LYS A 166 ? ILE A 172 ? LYS C 166 ILE C 172 E 1 GLU B 9 ? ASN B 12 ? GLU G 90 ASN G 93 E 2 ILE B 90 ? CYS B 93 ? ILE G 232 CYS G 235 F 1 ILE B 55 ? ALA B 56 ? ILE G 197 ALA G 198 F 2 VAL B 38 ? LYS B 39 ? VAL G 119 LYS G 120 F 3 ARG B 261 ? MET B 263 ? ARG G 431 MET G 433 F 4 ILE B 252 ? ASN B 254 ? ILE G 422 ASN G 424 G 1 VAL B 96 ? VAL B 99 ? VAL G 238 VAL G 241 G 2 ALA B 78 ? CYS B 82 ? ALA G 220 CYS G 224 G 3 LYS B 319 ? VAL B 321 ? LYS G 489 VAL G 491 H 1 LEU B 113 ? LEU B 115 ? LEU G 255 LEU G 257 H 2 THR B 273 ? LEU B 281 ? THR G 443 LEU G 451 H 3 HIS B 141 ? ILE B 151 ? HIS G 283 ILE G 293 H 4 HIS B 155 ? ILE B 158 ? HIS G 325 ILE G 328 H 5 THR B 244 ? LEU B 245 ? THR G 414 LEU G 415 I 1 ILE B 218 ? HIS B 219 ? ILE G 388 HIS G 389 I 2 THR B 182 ? PHE B 185 ? THR G 352 PHE G 355 I 3 THR B 297 ? PRO B 302 ? THR G 467 PRO G 472 I 4 LEU B 283 ? ARG B 285 ? LEU G 453 ARG G 455 J 1 PHE B 200 ? ASN B 201 ? PHE G 370 ASN G 371 J 2 PHE B 206 ? CYS B 209 ? PHE G 376 CYS G 379 J 3 CYS B 247 ? ARG B 250 ? CYS G 417 ARG G 420 K 1 GLN C 3 ? GLN C 6 ? GLN H 3 GLN H 6 K 2 CYS C 22 ? SER C 25 ? CYS H 22 SER H 25 L 1 GLU C 10 ? ARG C 12 ? GLU H 10 ARG H 12 L 2 THR C 119 ? VAL C 123 ? THR H 119 VAL H 123 L 3 ALA C 92 ? THR C 98 ? ALA H 92 THR H 98 L 4 ILE C 34 ? GLN C 39 ? ILE H 34 GLN H 39 L 5 LEU C 45 ? PHE C 51 ? LEU H 45 PHE H 51 L 6 ILE C 58 ? TYR C 60 ? ILE H 58 TYR H 60 M 1 GLU C 10 ? ARG C 12 ? GLU H 10 ARG H 12 M 2 THR C 119 ? VAL C 123 ? THR H 119 VAL H 123 M 3 ALA C 92 ? THR C 98 ? ALA H 92 THR H 98 M 4 TYR C 114 ? TRP C 115 ? TYR H 114 TRP H 115 N 1 VAL C 18 ? VAL C 20 ? VAL H 18 VAL H 20 N 2 THR C 78 ? LEU C 83 ? THR H 78 LEU H 83 N 3 VAL C 68 ? ASP C 73 ? VAL H 68 ASP H 73 O 1 SER C 132 ? LEU C 136 ? SER H 132 LEU H 136 O 2 THR C 147 ? TYR C 157 ? THR H 147 TYR H 157 O 3 TYR C 188 ? PRO C 197 ? TYR H 188 PRO H 197 O 4 VAL C 175 ? THR C 177 ? VAL H 175 THR H 177 P 1 SER C 132 ? LEU C 136 ? SER H 132 LEU H 136 P 2 THR C 147 ? TYR C 157 ? THR H 147 TYR H 157 P 3 TYR C 188 ? PRO C 197 ? TYR H 188 PRO H 197 P 4 VAL C 181 ? LEU C 182 ? VAL H 181 LEU H 182 Q 1 THR C 163 ? TRP C 166 ? THR H 163 TRP H 166 Q 2 TYR C 206 ? HIS C 212 ? TYR H 206 HIS H 212 Q 3 THR C 217 ? VAL C 223 ? THR H 217 VAL H 223 R 1 SER D 9 ? ALA D 12 ? SER L 10 ALA L 13 R 2 THR D 106 ? VAL D 110 ? THR L 107 VAL L 111 R 3 ALA D 85 ? ASP D 93 ? ALA L 86 ASP L 94 R 4 VAL D 34 ? GLN D 39 ? VAL L 35 GLN L 40 R 5 LYS D 46 ? ILE D 49 ? LYS L 47 ILE L 50 S 1 SER D 9 ? ALA D 12 ? SER L 10 ALA L 13 S 2 THR D 106 ? VAL D 110 ? THR L 107 VAL L 111 S 3 ALA D 85 ? ASP D 93 ? ALA L 86 ASP L 94 S 4 GLY D 99 ? PHE D 102 ? GLY L 100 PHE L 103 T 1 VAL D 18 ? SER D 23 ? VAL L 19 SER L 24 T 2 SER D 71 ? ILE D 76 ? SER L 72 ILE L 77 T 3 PHE D 63 ? SER D 68 ? PHE L 64 SER L 69 U 1 SER D 119 ? PHE D 123 ? SER L 120 PHE L 124 U 2 THR D 136 ? PHE D 144 ? THR L 137 PHE L 145 U 3 TYR D 177 ? SER D 184 ? TYR L 178 SER L 185 U 4 VAL D 164 ? THR D 166 ? VAL L 165 THR L 167 V 1 SER D 158 ? VAL D 160 ? SER L 159 VAL L 161 V 2 THR D 150 ? ALA D 155 ? THR L 151 ALA L 156 V 3 TYR D 196 ? HIS D 202 ? TYR L 197 HIS L 203 V 4 SER D 205 ? MET D 211 ? SER L 206 MET L 212 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 4 ? N VAL C 4 O GLN A 94 ? O GLN C 94 A 2 3 O LEU A 95 ? O LEU C 95 N ASP A 80 ? N ASP C 80 A 3 4 O ILE A 83 ? O ILE C 83 N LYS A 29 ? N LYS C 29 A 4 5 N TRP A 28 ? N TRP C 28 O LEU A 37 ? O LEU C 37 A 5 6 N GLN A 40 ? N GLN C 40 O PHE A 43 ? O PHE C 43 B 1 2 N VAL A 4 ? N VAL C 4 O GLN A 94 ? O GLN C 94 B 2 3 N GLY A 99 ? N GLY C 99 O GLU A 119 ? O GLU C 119 B 3 4 N LEU A 116 ? N LEU C 116 O LEU A 144 ? O LEU C 144 C 1 2 N LEU A 14 ? N LEU C 14 O LEU A 69 ? O LEU C 69 C 2 3 O ILE A 70 ? O ILE C 70 N ASP A 56 ? N ASP C 56 D 1 2 O ILE A 138 ? O ILE C 138 N CYS A 130 ? N CYS C 130 D 2 3 N GLN A 129 ? N GLN C 129 O THR A 160 ? O THR C 160 D 3 4 N CYS A 159 ? N CYS C 159 O PHE A 170 ? O PHE C 170 E 1 2 N GLU B 9 ? N GLU G 90 O CYS B 93 ? O CYS G 235 F 1 2 O ILE B 55 ? O ILE G 197 N LYS B 39 ? N LYS G 120 F 2 3 N VAL B 38 ? N VAL G 119 O MET B 263 ? O MET G 433 F 3 4 O ALA B 262 ? O ALA G 432 N ILE B 253 ? N ILE G 423 G 1 2 O VAL B 99 ? O VAL G 241 N ILE B 79 ? N ILE G 221 G 2 3 N ALA B 78 ? N ALA G 220 O VAL B 321 ? O VAL G 491 H 1 2 N LEU B 114 ? N LEU G 256 O GLY B 280 ? O GLY G 450 H 2 3 O ILE B 278 ? O ILE G 448 N VAL B 146 ? N VAL G 288 H 3 4 N THR B 149 ? N THR G 291 O ASN B 157 ? O ASN G 327 H 4 5 N CYS B 156 ? N CYS G 326 O LEU B 245 ? O LEU G 415 I 1 2 O HIS B 219 ? O HIS G 389 N ILE B 183 ? N ILE G 353 I 2 3 N GLU B 184 ? N GLU G 354 O PHE B 300 ? O PHE G 470 I 3 4 O ARG B 301 ? O ARG G 471 N THR B 284 ? N THR G 454 J 1 2 N PHE B 200 ? N PHE G 370 O PHE B 207 ? O PHE G 377 J 2 3 N TYR B 208 ? N TYR G 378 O ARG B 248 ? O ARG G 418 K 1 2 N GLN C 3 ? N GLN H 3 O SER C 25 ? O SER H 25 L 1 2 N ARG C 12 ? N ARG H 12 O THR C 122 ? O THR H 122 L 2 3 O THR C 119 ? O THR H 119 N TYR C 94 ? N TYR H 94 L 3 4 O VAL C 93 ? O VAL H 93 N GLN C 39 ? N GLN H 39 L 4 5 N ARG C 38 ? N ARG H 38 O GLU C 46 ? O GLU H 46 L 5 6 N GLY C 50 ? N GLY H 50 O ILE C 59 ? O ILE H 59 M 1 2 N ARG C 12 ? N ARG H 12 O THR C 122 ? O THR H 122 M 2 3 O THR C 119 ? O THR H 119 N TYR C 94 ? N TYR H 94 M 3 4 N THR C 98 ? N THR H 98 O TYR C 114 ? O TYR H 114 N 1 2 N VAL C 20 ? N VAL H 20 O MET C 81 ? O MET H 81 N 2 3 O GLU C 82 ? O GLU H 82 N SER C 69 ? N SER H 69 O 1 2 N LEU C 136 ? N LEU H 136 O GLY C 151 ? O GLY H 151 O 2 3 N ALA C 148 ? N ALA H 148 O VAL C 196 ? O VAL H 196 O 3 4 O VAL C 193 ? O VAL H 193 N HIS C 176 ? N HIS H 176 P 1 2 N LEU C 136 ? N LEU H 136 O GLY C 151 ? O GLY H 151 P 2 3 N ALA C 148 ? N ALA H 148 O VAL C 196 ? O VAL H 196 P 3 4 O SER C 189 ? O SER H 189 N VAL C 181 ? N VAL H 181 Q 1 2 N SER C 165 ? N SER H 165 O ASN C 209 ? O ASN H 209 Q 2 3 N VAL C 210 ? N VAL H 210 O VAL C 219 ? O VAL H 219 R 1 2 N VAL D 10 ? N VAL L 11 O THR D 109 ? O THR L 110 R 2 3 O LEU D 108 ? O LEU L 109 N ALA D 85 ? N ALA L 86 R 3 4 O GLY D 90 ? O GLY L 91 N SER D 35 ? N SER L 36 R 4 5 N GLN D 38 ? N GLN L 39 O LYS D 46 ? O LYS L 47 S 1 2 N VAL D 10 ? N VAL L 11 O THR D 109 ? O THR L 110 S 2 3 O LEU D 108 ? O LEU L 109 N ALA D 85 ? N ALA L 86 S 3 4 N THR D 91 ? N THR L 92 O LEU D 101 ? O LEU L 102 T 1 2 N CYS D 22 ? N CYS L 23 O ALA D 72 ? O ALA L 73 T 2 3 O ALA D 75 ? O ALA L 76 N SER D 64 ? N SER L 65 U 1 2 N PHE D 123 ? N PHE L 124 O VAL D 138 ? O VAL L 139 U 2 3 N LEU D 137 ? N LEU L 138 O LEU D 183 ? O LEU L 184 U 3 4 O TYR D 182 ? O TYR L 183 N GLU D 165 ? N GLU L 166 V 1 2 O VAL D 160 ? O VAL L 161 N TRP D 153 ? N TRP L 154 V 2 3 N LYS D 154 ? N LYS L 155 O SER D 197 ? O SER L 198 V 3 4 N TYR D 196 ? N TYR L 197 O MET D 211 ? O MET L 212 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG G 1000' AC2 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG G 1500' AC3 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG G 2000' AC4 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG G 2500' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 PRO B 66 ? PRO G 208 . ? 1_555 ? 2 AC1 4 ASN B 116 ? ASN G 258 . ? 1_555 ? 3 AC1 4 ASN B 201 ? ASN G 371 . ? 1_555 ? 4 AC1 4 ILE B 275 ? ILE G 445 . ? 1_555 ? 5 AC2 1 ASN B 130 ? ASN G 272 . ? 1_555 ? 6 AC3 3 ASN B 210 ? ASN G 380 . ? 1_555 ? 7 AC3 3 THR B 212 ? THR G 382 . ? 1_555 ? 8 AC3 3 LYS B 213 ? LYS G 383 . ? 1_555 ? 9 AC4 1 ASN B 271 ? ASN G 441 . ? 1_555 ? # _atom_sites.entry_id 3LQA _atom_sites.fract_transf_matrix[1][1] 0.010669 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.005321 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.006593 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . LYS A 1 2 ? -40.581 -21.412 -36.199 1.00 82.99 ? 2 LYS C N 1 ATOM 2 C CA . LYS A 1 2 ? -40.008 -20.383 -35.235 1.00 82.99 ? 2 LYS C CA 1 ATOM 3 C C . LYS A 1 2 ? -38.825 -20.907 -34.372 1.00 82.99 ? 2 LYS C C 1 ATOM 4 O O . LYS A 1 2 ? -39.035 -21.626 -33.376 1.00 82.99 ? 2 LYS C O 1 ATOM 5 C CB . LYS A 1 2 ? -41.069 -19.862 -34.274 1.00 112.30 ? 2 LYS C CB 1 ATOM 6 C CG . LYS A 1 2 ? -42.145 -19.042 -34.953 1.00 112.30 ? 2 LYS C CG 1 ATOM 7 C CD . LYS A 1 2 ? -43.187 -18.554 -33.918 1.00 112.30 ? 2 LYS C CD 1 ATOM 8 C CE . LYS A 1 2 ? -44.289 -17.716 -34.549 1.00 112.30 ? 2 LYS C CE 1 ATOM 9 N NZ . LYS A 1 2 ? -45.266 -17.359 -33.514 1.00 112.30 ? 2 LYS C NZ 1 ATOM 10 N N . VAL A 1 3 ? -37.606 -20.476 -34.720 1.00 106.60 ? 3 VAL C N 1 ATOM 11 C CA . VAL A 1 3 ? -36.416 -20.988 -34.077 1.00 106.60 ? 3 VAL C CA 1 ATOM 12 C C . VAL A 1 3 ? -35.457 -20.093 -33.324 1.00 106.60 ? 3 VAL C C 1 ATOM 13 O O . VAL A 1 3 ? -35.051 -19.058 -33.855 1.00 106.60 ? 3 VAL C O 1 ATOM 14 C CB . VAL A 1 3 ? -35.585 -21.748 -35.125 1.00 69.50 ? 3 VAL C CB 1 ATOM 15 C CG1 . VAL A 1 3 ? -34.364 -22.291 -34.532 1.00 69.50 ? 3 VAL C CG1 1 ATOM 16 C CG2 . VAL A 1 3 ? -36.343 -22.910 -35.627 1.00 69.50 ? 3 VAL C CG2 1 ATOM 17 N N . VAL A 1 4 ? -35.108 -20.490 -32.079 1.00 110.08 ? 4 VAL C N 1 ATOM 18 C CA . VAL A 1 4 ? -34.063 -19.763 -31.351 1.00 110.08 ? 4 VAL C CA 1 ATOM 19 C C . VAL A 1 4 ? -33.095 -20.830 -30.851 1.00 110.08 ? 4 VAL C C 1 ATOM 20 O O . VAL A 1 4 ? -33.451 -21.990 -30.594 1.00 110.08 ? 4 VAL C O 1 ATOM 21 C CB . VAL A 1 4 ? -34.584 -19.021 -30.125 1.00 38.18 ? 4 VAL C CB 1 ATOM 22 C CG1 . VAL A 1 4 ? -35.649 -18.000 -30.627 1.00 38.18 ? 4 VAL C CG1 1 ATOM 23 C CG2 . VAL A 1 4 ? -35.143 -20.030 -29.039 1.00 38.18 ? 4 VAL C CG2 1 ATOM 24 N N . LEU A 1 5 ? -31.909 -20.338 -30.551 1.00 93.81 ? 5 LEU C N 1 ATOM 25 C CA . LEU A 1 5 ? -30.756 -21.132 -30.161 1.00 93.81 ? 5 LEU C CA 1 ATOM 26 C C . LEU A 1 5 ? -30.254 -20.752 -28.756 1.00 93.81 ? 5 LEU C C 1 ATOM 27 O O . LEU A 1 5 ? -30.216 -19.565 -28.418 1.00 93.81 ? 5 LEU C O 1 ATOM 28 C CB . LEU A 1 5 ? -29.689 -20.868 -31.201 1.00 75.00 ? 5 LEU C CB 1 ATOM 29 C CG . LEU A 1 5 ? -30.206 -21.287 -32.563 1.00 75.00 ? 5 LEU C CG 1 ATOM 30 C CD1 . LEU A 1 5 ? -29.196 -20.938 -33.573 1.00 75.00 ? 5 LEU C CD1 1 ATOM 31 C CD2 . LEU A 1 5 ? -30.489 -22.761 -32.595 1.00 75.00 ? 5 LEU C CD2 1 ATOM 32 N N . GLY A 1 6 ? -29.852 -21.717 -27.935 1.00 106.22 ? 6 GLY C N 1 ATOM 33 C CA . GLY A 1 6 ? -29.369 -21.367 -26.610 1.00 106.22 ? 6 GLY C CA 1 ATOM 34 C C . GLY A 1 6 ? -28.048 -22.060 -26.443 1.00 106.22 ? 6 GLY C C 1 ATOM 35 O O . GLY A 1 6 ? -27.882 -23.172 -26.936 1.00 106.22 ? 6 GLY C O 1 ATOM 36 N N . LYS A 1 7 ? -27.111 -21.385 -25.785 1.00 80.44 ? 7 LYS C N 1 ATOM 37 C CA . LYS A 1 7 ? -25.741 -21.873 -25.533 1.00 80.44 ? 7 LYS C CA 1 ATOM 38 C C . LYS A 1 7 ? -25.793 -22.985 -24.482 1.00 80.44 ? 7 LYS C C 1 ATOM 39 O O . LYS A 1 7 ? -26.700 -23.013 -23.636 1.00 80.44 ? 7 LYS C O 1 ATOM 40 C CB . LYS A 1 7 ? -24.913 -20.801 -24.902 1.00 121.26 ? 7 LYS C CB 1 ATOM 41 C CG . LYS A 1 7 ? -24.740 -19.561 -25.666 1.00 121.26 ? 7 LYS C CG 1 ATOM 42 C CD . LYS A 1 7 ? -23.879 -18.700 -24.787 1.00 121.26 ? 7 LYS C CD 1 ATOM 43 C CE . LYS A 1 7 ? -23.585 -17.383 -25.388 1.00 121.26 ? 7 LYS C CE 1 ATOM 44 N NZ . LYS A 1 7 ? -24.865 -16.628 -25.439 1.00 121.26 ? 7 LYS C NZ 1 ATOM 45 N N . LYS A 1 8 ? -24.872 -23.931 -24.541 1.00 89.93 ? 8 LYS C N 1 ATOM 46 C CA . LYS A 1 8 ? -24.868 -24.963 -23.515 1.00 89.93 ? 8 LYS C CA 1 ATOM 47 C C . LYS A 1 8 ? -24.505 -24.456 -22.138 1.00 89.93 ? 8 LYS C C 1 ATOM 48 O O . LYS A 1 8 ? -23.704 -23.565 -21.979 1.00 89.93 ? 8 LYS C O 1 ATOM 49 C CB . LYS A 1 8 ? -23.902 -26.067 -23.905 1.00 76.18 ? 8 LYS C CB 1 ATOM 50 C CG . LYS A 1 8 ? -23.794 -27.210 -22.944 1.00 76.18 ? 8 LYS C CG 1 ATOM 51 C CD . LYS A 1 8 ? -22.796 -28.171 -23.524 1.00 76.18 ? 8 LYS C CD 1 ATOM 52 C CE . LYS A 1 8 ? -22.602 -29.378 -22.658 1.00 76.18 ? 8 LYS C CE 1 ATOM 53 N NZ . LYS A 1 8 ? -21.887 -30.434 -23.390 1.00 76.18 ? 8 LYS C NZ 1 ATOM 54 N N . GLY A 1 9 ? -25.240 -24.935 -21.164 1.00 85.11 ? 9 GLY C N 1 ATOM 55 C CA . GLY A 1 9 ? -24.997 -24.659 -19.760 1.00 85.11 ? 9 GLY C CA 1 ATOM 56 C C . GLY A 1 9 ? -25.732 -23.422 -19.282 1.00 85.11 ? 9 GLY C C 1 ATOM 57 O O . GLY A 1 9 ? -26.002 -23.274 -18.083 1.00 85.11 ? 9 GLY C O 1 ATOM 58 N N . ASP A 1 10 ? -26.286 -22.702 -20.261 1.00 72.73 ? 10 ASP C N 1 ATOM 59 C CA . ASP A 1 10 ? -26.998 -21.431 -20.072 1.00 72.73 ? 10 ASP C CA 1 ATOM 60 C C . ASP A 1 10 ? -28.480 -21.513 -19.823 1.00 72.73 ? 10 ASP C C 1 ATOM 61 O O . ASP A 1 10 ? -29.072 -22.583 -19.732 1.00 72.73 ? 10 ASP C O 1 ATOM 62 C CB . ASP A 1 10 ? -26.676 -20.352 -21.126 1.00 102.24 ? 10 ASP C CB 1 ATOM 63 C CG . ASP A 1 10 ? -25.249 -19.805 -20.981 1.00 102.24 ? 10 ASP C CG 1 ATOM 64 O OD1 . ASP A 1 10 ? -24.601 -20.068 -19.949 1.00 102.24 ? 10 ASP C OD1 1 ATOM 65 O OD2 . ASP A 1 10 ? -24.781 -19.023 -21.833 1.00 102.24 ? 10 ASP C OD2 1 ATOM 66 N N . THR A 1 11 ? -29.073 -20.363 -19.672 1.00 110.36 ? 11 THR C N 1 ATOM 67 C CA . THR A 1 11 ? -30.460 -20.328 -19.351 1.00 110.36 ? 11 THR C CA 1 ATOM 68 C C . THR A 1 11 ? -31.166 -19.583 -20.457 1.00 110.36 ? 11 THR C C 1 ATOM 69 O O . THR A 1 11 ? -30.763 -18.471 -20.846 1.00 110.36 ? 11 THR C O 1 ATOM 70 C CB . THR A 1 11 ? -30.678 -19.620 -18.020 1.00 62.31 ? 11 THR C CB 1 ATOM 71 O OG1 . THR A 1 11 ? -29.976 -20.329 -17.007 1.00 62.31 ? 11 THR C OG1 1 ATOM 72 C CG2 . THR A 1 11 ? -32.141 -19.523 -17.670 1.00 62.31 ? 11 THR C CG2 1 ATOM 73 N N . VAL A 1 12 ? -32.245 -20.259 -20.931 1.00 76.87 ? 12 VAL C N 1 ATOM 74 C CA . VAL A 1 12 ? -33.086 -19.907 -22.103 1.00 76.87 ? 12 VAL C CA 1 ATOM 75 C C . VAL A 1 12 ? -34.539 -19.909 -21.808 1.00 76.87 ? 12 VAL C C 1 ATOM 76 O O . VAL A 1 12 ? -35.058 -20.707 -21.020 1.00 76.87 ? 12 VAL C O 1 ATOM 77 C CB . VAL A 1 12 ? -33.025 -20.953 -23.224 1.00 53.36 ? 12 VAL C CB 1 ATOM 78 C CG1 . VAL A 1 12 ? -33.503 -22.328 -22.709 1.00 53.36 ? 12 VAL C CG1 1 ATOM 79 C CG2 . VAL A 1 12 ? -33.974 -20.552 -24.285 1.00 53.36 ? 12 VAL C CG2 1 ATOM 80 N N . GLU A 1 13 ? -35.176 -18.910 -22.392 1.00 96.39 ? 13 GLU C N 1 ATOM 81 C CA . GLU A 1 13 ? -36.594 -18.791 -22.210 1.00 96.39 ? 13 GLU C CA 1 ATOM 82 C C . GLU A 1 13 ? -37.472 -18.772 -23.479 1.00 96.39 ? 13 GLU C C 1 ATOM 83 O O . GLU A 1 13 ? -37.182 -18.069 -24.422 1.00 96.39 ? 13 GLU C O 1 ATOM 84 C CB . GLU A 1 13 ? -36.811 -17.634 -21.250 1.00 83.08 ? 13 GLU C CB 1 ATOM 85 C CG . GLU A 1 13 ? -38.183 -17.255 -20.858 1.00 83.08 ? 13 GLU C CG 1 ATOM 86 C CD . GLU A 1 13 ? -38.100 -16.109 -19.926 1.00 83.08 ? 13 GLU C CD 1 ATOM 87 O OE1 . GLU A 1 13 ? -39.124 -15.512 -19.620 1.00 83.08 ? 13 GLU C OE1 1 ATOM 88 O OE2 . GLU A 1 13 ? -36.992 -15.854 -19.424 1.00 83.08 ? 13 GLU C OE2 1 ATOM 89 N N . LEU A 1 14 ? -38.514 -19.600 -23.494 1.00 116.63 ? 14 LEU C N 1 ATOM 90 C CA . LEU A 1 14 ? -39.458 -19.711 -24.596 1.00 116.63 ? 14 LEU C CA 1 ATOM 91 C C . LEU A 1 14 ? -40.695 -18.921 -24.207 1.00 116.63 ? 14 LEU C C 1 ATOM 92 O O . LEU A 1 14 ? -41.210 -19.097 -23.113 1.00 116.63 ? 14 LEU C O 1 ATOM 93 C CB . LEU A 1 14 ? -39.786 -21.174 -24.819 1.00 57.37 ? 14 LEU C CB 1 ATOM 94 C CG . LEU A 1 14 ? -38.627 -22.071 -25.169 1.00 57.37 ? 14 LEU C CG 1 ATOM 95 C CD1 . LEU A 1 14 ? -39.090 -23.492 -25.322 1.00 57.37 ? 14 LEU C CD1 1 ATOM 96 C CD2 . LEU A 1 14 ? -38.061 -21.597 -26.469 1.00 57.37 ? 14 LEU C CD2 1 ATOM 97 N N . THR A 1 15 ? -41.212 -18.127 -25.147 1.00 127.59 ? 15 THR C N 1 ATOM 98 C CA . THR A 1 15 ? -42.322 -17.190 -24.915 1.00 127.59 ? 15 THR C CA 1 ATOM 99 C C . THR A 1 15 ? -43.718 -17.588 -25.370 1.00 127.59 ? 15 THR C C 1 ATOM 100 O O . THR A 1 15 ? -43.908 -18.069 -26.460 1.00 127.59 ? 15 THR C O 1 ATOM 101 C CB . THR A 1 15 ? -42.035 -15.828 -25.607 1.00 84.15 ? 15 THR C CB 1 ATOM 102 O OG1 . THR A 1 15 ? -40.732 -15.366 -25.259 1.00 84.15 ? 15 THR C OG1 1 ATOM 103 C CG2 . THR A 1 15 ? -43.047 -14.774 -25.190 1.00 84.15 ? 15 THR C CG2 1 ATOM 104 N N . CYS A 1 16 ? -44.679 -17.465 -24.478 1.00 84.33 ? 16 CYS C N 1 ATOM 105 C CA . CYS A 1 16 ? -46.077 -17.726 -24.782 1.00 84.33 ? 16 CYS C CA 1 ATOM 106 C C . CYS A 1 16 ? -47.055 -16.541 -24.553 1.00 84.33 ? 16 CYS C C 1 ATOM 107 O O . CYS A 1 16 ? -47.001 -15.872 -23.522 1.00 84.33 ? 16 CYS C O 1 ATOM 108 C CB . CYS A 1 16 ? -46.546 -18.970 -24.065 1.00 174.62 ? 16 CYS C CB 1 ATOM 109 S SG . CYS A 1 16 ? -47.623 -19.930 -25.146 1.00 174.62 ? 16 CYS C SG 1 ATOM 110 N N . THR A 1 17 ? -47.900 -16.263 -25.547 1.00 90.99 ? 17 THR C N 1 ATOM 111 C CA . THR A 1 17 ? -48.880 -15.174 -25.532 1.00 90.99 ? 17 THR C CA 1 ATOM 112 C C . THR A 1 17 ? -50.394 -15.454 -25.665 1.00 90.99 ? 17 THR C C 1 ATOM 113 O O . THR A 1 17 ? -50.819 -16.208 -26.526 1.00 90.99 ? 17 THR C O 1 ATOM 114 C CB . THR A 1 17 ? -48.485 -14.065 -26.475 1.00 81.93 ? 17 THR C CB 1 ATOM 115 O OG1 . THR A 1 17 ? -47.211 -13.563 -26.050 1.00 81.93 ? 17 THR C OG1 1 ATOM 116 C CG2 . THR A 1 17 ? -49.495 -12.884 -26.377 1.00 81.93 ? 17 THR C CG2 1 ATOM 117 N N . ALA A 1 18 ? -51.198 -14.889 -24.767 1.00 96.77 ? 18 ALA C N 1 ATOM 118 C CA . ALA A 1 18 ? -52.637 -15.077 -24.774 1.00 96.77 ? 18 ALA C CA 1 ATOM 119 C C . ALA A 1 18 ? -53.254 -13.816 -25.375 1.00 96.77 ? 18 ALA C C 1 ATOM 120 O O . ALA A 1 18 ? -52.665 -12.739 -25.376 1.00 96.77 ? 18 ALA C O 1 ATOM 121 C CB . ALA A 1 18 ? -53.144 -15.299 -23.380 1.00 86.70 ? 18 ALA C CB 1 ATOM 122 N N . SER A 1 19 ? -54.477 -13.983 -25.846 1.00 128.50 ? 19 SER C N 1 ATOM 123 C CA . SER A 1 19 ? -55.264 -13.013 -26.586 1.00 128.50 ? 19 SER C CA 1 ATOM 124 C C . SER A 1 19 ? -55.538 -11.733 -25.851 1.00 128.50 ? 19 SER C C 1 ATOM 125 O O . SER A 1 19 ? -55.591 -10.666 -26.472 1.00 128.50 ? 19 SER C O 1 ATOM 126 C CB . SER A 1 19 ? -56.496 -13.670 -27.150 1.00 99.70 ? 19 SER C CB 1 ATOM 127 O OG . SER A 1 19 ? -56.072 -14.593 -28.152 1.00 99.70 ? 19 SER C OG 1 ATOM 128 N N . GLN A 1 20 ? -55.822 -11.825 -24.561 1.00 112.29 ? 20 GLN C N 1 ATOM 129 C CA . GLN A 1 20 ? -56.044 -10.596 -23.802 1.00 112.29 ? 20 GLN C CA 1 ATOM 130 C C . GLN A 1 20 ? -55.163 -10.726 -22.580 1.00 112.29 ? 20 GLN C C 1 ATOM 131 O O . GLN A 1 20 ? -54.811 -11.825 -22.179 1.00 112.29 ? 20 GLN C O 1 ATOM 132 C CB . GLN A 1 20 ? -57.498 -10.485 -23.386 1.00 131.44 ? 20 GLN C CB 1 ATOM 133 C CG . GLN A 1 20 ? -57.980 -11.617 -22.515 1.00 131.44 ? 20 GLN C CG 1 ATOM 134 C CD . GLN A 1 20 ? -59.488 -11.555 -22.325 1.00 131.44 ? 20 GLN C CD 1 ATOM 135 O OE1 . GLN A 1 20 ? -60.238 -11.250 -23.268 1.00 131.44 ? 20 GLN C OE1 1 ATOM 136 N NE2 . GLN A 1 20 ? -59.945 -11.837 -21.097 1.00 131.44 ? 20 GLN C NE2 1 ATOM 137 N N . LYS A 1 21 ? -54.821 -9.598 -21.973 1.00 107.02 ? 21 LYS C N 1 ATOM 138 C CA . LYS A 1 21 ? -53.863 -9.646 -20.885 1.00 107.02 ? 21 LYS C CA 1 ATOM 139 C C . LYS A 1 21 ? -54.690 -10.093 -19.693 1.00 107.02 ? 21 LYS C C 1 ATOM 140 O O . LYS A 1 21 ? -55.098 -9.320 -18.816 1.00 107.02 ? 21 LYS C O 1 ATOM 141 C CB . LYS A 1 21 ? -53.322 -8.203 -20.764 1.00 100.40 ? 21 LYS C CB 1 ATOM 142 C CG . LYS A 1 21 ? -54.441 -7.158 -20.442 1.00 100.40 ? 21 LYS C CG 1 ATOM 143 C CD . LYS A 1 21 ? -53.941 -5.708 -20.366 1.00 100.40 ? 21 LYS C CD 1 ATOM 144 C CE . LYS A 1 21 ? -55.062 -4.718 -19.942 1.00 100.40 ? 21 LYS C CE 1 ATOM 145 N NZ . LYS A 1 21 ? -55.514 -5.023 -18.544 1.00 100.40 ? 21 LYS C NZ 1 ATOM 146 N N . LYS A 1 22 ? -54.918 -11.407 -19.726 1.00 122.23 ? 22 LYS C N 1 ATOM 147 C CA . LYS A 1 22 ? -55.692 -12.152 -18.744 1.00 122.23 ? 22 LYS C CA 1 ATOM 148 C C . LYS A 1 22 ? -55.178 -13.524 -18.325 1.00 122.23 ? 22 LYS C C 1 ATOM 149 O O . LYS A 1 22 ? -54.668 -14.235 -19.189 1.00 122.23 ? 22 LYS C O 1 ATOM 150 C CB . LYS A 1 22 ? -57.127 -12.298 -19.224 1.00 125.72 ? 22 LYS C CB 1 ATOM 151 C CG . LYS A 1 22 ? -57.999 -12.870 -18.140 1.00 125.72 ? 22 LYS C CG 1 ATOM 152 C CD . LYS A 1 22 ? -59.421 -13.033 -18.565 1.00 125.72 ? 22 LYS C CD 1 ATOM 153 C CE . LYS A 1 22 ? -60.155 -13.485 -17.351 1.00 125.72 ? 22 LYS C CE 1 ATOM 154 N NZ . LYS A 1 22 ? -59.996 -12.375 -16.341 1.00 125.72 ? 22 LYS C NZ 1 ATOM 155 N N . SER A 1 23 ? -55.251 -13.928 -17.057 1.00 117.12 ? 23 SER C N 1 ATOM 156 C CA . SER A 1 23 ? -54.844 -15.315 -16.834 1.00 117.12 ? 23 SER C CA 1 ATOM 157 C C . SER A 1 23 ? -55.790 -16.377 -17.386 1.00 117.12 ? 23 SER C C 1 ATOM 158 O O . SER A 1 23 ? -57.001 -16.316 -17.250 1.00 117.12 ? 23 SER C O 1 ATOM 159 C CB . SER A 1 23 ? -54.675 -15.656 -15.373 1.00 76.96 ? 23 SER C CB 1 ATOM 160 O OG . SER A 1 23 ? -54.310 -17.038 -15.320 1.00 76.96 ? 23 SER C OG 1 ATOM 161 N N . ILE A 1 24 ? -55.162 -17.281 -18.107 1.00 67.93 ? 24 ILE C N 1 ATOM 162 C CA . ILE A 1 24 ? -55.635 -18.477 -18.774 1.00 67.93 ? 24 ILE C CA 1 ATOM 163 C C . ILE A 1 24 ? -55.031 -19.793 -18.359 1.00 67.93 ? 24 ILE C C 1 ATOM 164 O O . ILE A 1 24 ? -53.855 -19.782 -18.192 1.00 67.93 ? 24 ILE C O 1 ATOM 165 C CB . ILE A 1 24 ? -55.644 -18.337 -20.315 1.00 110.36 ? 24 ILE C CB 1 ATOM 166 C CG1 . ILE A 1 24 ? -56.570 -17.174 -20.706 1.00 110.36 ? 24 ILE C CG1 1 ATOM 167 C CG2 . ILE A 1 24 ? -56.120 -19.632 -20.945 1.00 110.36 ? 24 ILE C CG2 1 ATOM 168 C CD1 . ILE A 1 24 ? -56.528 -16.736 -22.163 1.00 110.36 ? 24 ILE C CD1 1 ATOM 169 N N . GLN A 1 25 ? -55.729 -20.868 -18.038 1.00 79.98 ? 25 GLN C N 1 ATOM 170 C CA . GLN A 1 25 ? -54.944 -22.100 -17.766 1.00 79.98 ? 25 GLN C CA 1 ATOM 171 C C . GLN A 1 25 ? -54.175 -22.387 -19.072 1.00 79.98 ? 25 GLN C C 1 ATOM 172 O O . GLN A 1 25 ? -54.783 -22.348 -20.134 1.00 79.98 ? 25 GLN C O 1 ATOM 173 C CB . GLN A 1 25 ? -55.890 -23.261 -17.472 1.00 107.65 ? 25 GLN C CB 1 ATOM 174 C CG . GLN A 1 25 ? -55.262 -24.587 -17.175 1.00 107.65 ? 25 GLN C CG 1 ATOM 175 C CD . GLN A 1 25 ? -56.317 -25.629 -16.906 1.00 107.65 ? 25 GLN C CD 1 ATOM 176 O OE1 . GLN A 1 25 ? -57.338 -25.682 -17.582 1.00 107.65 ? 25 GLN C OE1 1 ATOM 177 N NE2 . GLN A 1 25 ? -56.088 -26.458 -15.902 1.00 107.65 ? 25 GLN C NE2 1 ATOM 178 N N . PHE A 1 26 ? -52.866 -22.730 -18.956 1.00 175.44 ? 26 PHE C N 1 ATOM 179 C CA . PHE A 1 26 ? -51.912 -22.948 -20.095 1.00 175.44 ? 26 PHE C CA 1 ATOM 180 C C . PHE A 1 26 ? -51.072 -24.154 -19.687 1.00 175.44 ? 26 PHE C C 1 ATOM 181 O O . PHE A 1 26 ? -50.960 -24.477 -18.510 1.00 175.44 ? 26 PHE C O 1 ATOM 182 C CB . PHE A 1 26 ? -50.865 -21.815 -20.203 1.00 83.63 ? 26 PHE C CB 1 ATOM 183 C CG . PHE A 1 26 ? -49.839 -21.807 -19.071 1.00 83.63 ? 26 PHE C CG 1 ATOM 184 C CD1 . PHE A 1 26 ? -50.045 -21.106 -17.911 1.00 83.63 ? 26 PHE C CD1 1 ATOM 185 C CD2 . PHE A 1 26 ? -48.637 -22.481 -19.195 1.00 83.63 ? 26 PHE C CD2 1 ATOM 186 C CE1 . PHE A 1 26 ? -49.086 -21.085 -16.894 1.00 83.63 ? 26 PHE C CE1 1 ATOM 187 C CE2 . PHE A 1 26 ? -47.693 -22.450 -18.183 1.00 83.63 ? 26 PHE C CE2 1 ATOM 188 C CZ . PHE A 1 26 ? -47.927 -21.754 -17.039 1.00 83.63 ? 26 PHE C CZ 1 ATOM 189 N N . HIS A 1 27 ? -50.437 -24.820 -20.624 1.00 88.73 ? 27 HIS C N 1 ATOM 190 C CA . HIS A 1 27 ? -49.661 -25.940 -20.155 1.00 88.73 ? 27 HIS C CA 1 ATOM 191 C C . HIS A 1 27 ? -48.472 -26.150 -21.175 1.00 88.73 ? 27 HIS C C 1 ATOM 192 O O . HIS A 1 27 ? -48.538 -25.668 -22.308 1.00 88.73 ? 27 HIS C O 1 ATOM 193 C CB . HIS A 1 27 ? -50.647 -27.083 -20.081 1.00 90.07 ? 27 HIS C CB 1 ATOM 194 C CG . HIS A 1 27 ? -50.217 -28.194 -19.204 1.00 90.07 ? 27 HIS C CG 1 ATOM 195 N ND1 . HIS A 1 27 ? -49.086 -28.949 -19.428 1.00 90.07 ? 27 HIS C ND1 1 ATOM 196 C CD2 . HIS A 1 27 ? -50.793 -28.682 -18.082 1.00 90.07 ? 27 HIS C CD2 1 ATOM 197 C CE1 . HIS A 1 27 ? -48.987 -29.857 -18.472 1.00 90.07 ? 27 HIS C CE1 1 ATOM 198 N NE2 . HIS A 1 27 ? -50.011 -29.717 -17.645 1.00 90.07 ? 27 HIS C NE2 1 ATOM 199 N N . TRP A 1 28 ? -47.378 -26.826 -20.830 1.00 83.27 ? 28 TRP C N 1 ATOM 200 C CA . TRP A 1 28 ? -46.292 -27.009 -21.828 1.00 83.27 ? 28 TRP C CA 1 ATOM 201 C C . TRP A 1 28 ? -45.898 -28.383 -22.224 1.00 83.27 ? 28 TRP C C 1 ATOM 202 O O . TRP A 1 28 ? -45.976 -29.341 -21.428 1.00 83.27 ? 28 TRP C O 1 ATOM 203 C CB . TRP A 1 28 ? -44.950 -26.252 -21.571 1.00 83.84 ? 28 TRP C CB 1 ATOM 204 C CG . TRP A 1 28 ? -44.840 -24.730 -21.697 1.00 83.84 ? 28 TRP C CG 1 ATOM 205 C CD1 . TRP A 1 28 ? -45.104 -23.758 -20.769 1.00 83.84 ? 28 TRP C CD1 1 ATOM 206 C CD2 . TRP A 1 28 ? -44.277 -24.050 -22.824 1.00 83.84 ? 28 TRP C CD2 1 ATOM 207 N NE1 . TRP A 1 28 ? -44.740 -22.519 -21.262 1.00 83.84 ? 28 TRP C NE1 1 ATOM 208 C CE2 . TRP A 1 28 ? -44.232 -22.682 -22.522 1.00 83.84 ? 28 TRP C CE2 1 ATOM 209 C CE3 . TRP A 1 28 ? -43.799 -24.476 -24.060 1.00 83.84 ? 28 TRP C CE3 1 ATOM 210 C CZ2 . TRP A 1 28 ? -43.731 -21.743 -23.417 1.00 83.84 ? 28 TRP C CZ2 1 ATOM 211 C CZ3 . TRP A 1 28 ? -43.298 -23.545 -24.937 1.00 83.84 ? 28 TRP C CZ3 1 ATOM 212 C CH2 . TRP A 1 28 ? -43.268 -22.193 -24.612 1.00 83.84 ? 28 TRP C CH2 1 ATOM 213 N N . LYS A 1 29 ? -45.650 -28.468 -23.535 1.00 78.75 ? 29 LYS C N 1 ATOM 214 C CA . LYS A 1 29 ? -45.219 -29.681 -24.158 1.00 78.75 ? 29 LYS C CA 1 ATOM 215 C C . LYS A 1 29 ? -44.029 -29.605 -25.133 1.00 78.75 ? 29 LYS C C 1 ATOM 216 O O . LYS A 1 29 ? -43.906 -28.687 -25.972 1.00 78.75 ? 29 LYS C O 1 ATOM 217 C CB . LYS A 1 29 ? -46.425 -30.297 -24.852 1.00 97.26 ? 29 LYS C CB 1 ATOM 218 C CG . LYS A 1 29 ? -47.465 -30.826 -23.886 1.00 97.26 ? 29 LYS C CG 1 ATOM 219 C CD . LYS A 1 29 ? -48.679 -31.445 -24.577 1.00 97.26 ? 29 LYS C CD 1 ATOM 220 C CE . LYS A 1 29 ? -49.641 -31.934 -23.527 1.00 97.26 ? 29 LYS C CE 1 ATOM 221 N NZ . LYS A 1 29 ? -50.808 -32.632 -24.056 1.00 97.26 ? 29 LYS C NZ 1 ATOM 222 N N . ASN A 1 30 ? -43.295 -30.722 -25.096 1.00 92.39 ? 30 ASN C N 1 ATOM 223 C CA . ASN A 1 30 ? -42.074 -31.124 -25.831 1.00 92.39 ? 30 ASN C CA 1 ATOM 224 C C . ASN A 1 30 ? -42.429 -31.846 -27.147 1.00 92.39 ? 30 ASN C C 1 ATOM 225 O O . ASN A 1 30 ? -43.591 -31.891 -27.512 1.00 92.39 ? 30 ASN C O 1 ATOM 226 C CB . ASN A 1 30 ? -41.155 -31.952 -24.917 1.00 92.58 ? 30 ASN C CB 1 ATOM 227 C CG . ASN A 1 30 ? -41.806 -33.208 -24.433 1.00 92.58 ? 30 ASN C CG 1 ATOM 228 O OD1 . ASN A 1 30 ? -43.021 -33.319 -24.451 1.00 92.58 ? 30 ASN C OD1 1 ATOM 229 N ND2 . ASN A 1 30 ? -41.005 -34.163 -23.969 1.00 92.58 ? 30 ASN C ND2 1 ATOM 230 N N . SER A 1 31 ? -41.469 -32.352 -27.916 1.00 126.73 ? 31 SER C N 1 ATOM 231 C CA . SER A 1 31 ? -41.879 -32.910 -29.199 1.00 126.73 ? 31 SER C CA 1 ATOM 232 C C . SER A 1 31 ? -42.871 -34.063 -29.039 1.00 126.73 ? 31 SER C C 1 ATOM 233 O O . SER A 1 31 ? -43.842 -34.122 -29.787 1.00 126.73 ? 31 SER C O 1 ATOM 234 C CB . SER A 1 31 ? -40.636 -33.453 -29.893 1.00 108.95 ? 31 SER C CB 1 ATOM 235 O OG . SER A 1 31 ? -40.948 -34.010 -31.154 1.00 108.95 ? 31 SER C OG 1 ATOM 236 N N . ASN A 1 32 ? -42.679 -34.943 -28.069 1.00 111.25 ? 32 ASN C N 1 ATOM 237 C CA . ASN A 1 32 ? -43.673 -35.977 -27.762 1.00 111.25 ? 32 ASN C CA 1 ATOM 238 C C . ASN A 1 32 ? -44.660 -35.184 -26.941 1.00 111.25 ? 32 ASN C C 1 ATOM 239 O O . ASN A 1 32 ? -44.246 -34.169 -26.399 1.00 111.25 ? 32 ASN C O 1 ATOM 240 C CB . ASN A 1 32 ? -43.090 -37.162 -27.001 1.00 129.29 ? 32 ASN C CB 1 ATOM 241 C CG . ASN A 1 32 ? -42.169 -37.996 -27.866 1.00 129.29 ? 32 ASN C CG 1 ATOM 242 O OD1 . ASN A 1 32 ? -42.233 -37.935 -29.091 1.00 129.29 ? 32 ASN C OD1 1 ATOM 243 N ND2 . ASN A 1 32 ? -41.309 -38.783 -27.235 1.00 129.29 ? 32 ASN C ND2 1 ATOM 244 N N . GLN A 1 33 ? -45.910 -35.623 -26.773 1.00 144.73 ? 33 GLN C N 1 ATOM 245 C CA . GLN A 1 33 ? -46.873 -34.780 -26.048 1.00 144.73 ? 33 GLN C CA 1 ATOM 246 C C . GLN A 1 33 ? -46.691 -35.198 -24.576 1.00 144.73 ? 33 GLN C C 1 ATOM 247 O O . GLN A 1 33 ? -47.551 -35.819 -23.963 1.00 144.73 ? 33 GLN C O 1 ATOM 248 C CB . GLN A 1 33 ? -48.322 -35.128 -26.446 1.00 97.51 ? 33 GLN C CB 1 ATOM 249 C CG . GLN A 1 33 ? -48.777 -34.750 -27.857 1.00 97.51 ? 33 GLN C CG 1 ATOM 250 C CD . GLN A 1 33 ? -48.938 -33.262 -28.106 1.00 97.51 ? 33 GLN C CD 1 ATOM 251 O OE1 . GLN A 1 33 ? -48.416 -32.710 -29.100 1.00 97.51 ? 33 GLN C OE1 1 ATOM 252 N NE2 . GLN A 1 33 ? -49.706 -32.602 -27.224 1.00 97.51 ? 33 GLN C NE2 1 ATOM 253 N N . ILE A 1 34 ? -45.520 -34.804 -24.054 1.00 115.57 ? 34 ILE C N 1 ATOM 254 C CA . ILE A 1 34 ? -45.004 -34.935 -22.674 1.00 115.57 ? 34 ILE C CA 1 ATOM 255 C C . ILE A 1 34 ? -44.875 -33.578 -22.034 1.00 115.57 ? 34 ILE C C 1 ATOM 256 O O . ILE A 1 34 ? -44.288 -32.633 -22.582 1.00 115.57 ? 34 ILE C O 1 ATOM 257 C CB . ILE A 1 34 ? -43.732 -35.793 -22.423 1.00 117.92 ? 34 ILE C CB 1 ATOM 258 C CG1 . ILE A 1 34 ? -43.918 -37.228 -22.847 1.00 117.92 ? 34 ILE C CG1 1 ATOM 259 C CG2 . ILE A 1 34 ? -43.388 -35.760 -21.010 1.00 117.92 ? 34 ILE C CG2 1 ATOM 260 C CD1 . ILE A 1 34 ? -42.622 -37.996 -22.824 1.00 117.92 ? 34 ILE C CD1 1 ATOM 261 N N . LYS A 1 35 ? -45.437 -33.514 -20.840 1.00 106.95 ? 35 LYS C N 1 ATOM 262 C CA . LYS A 1 35 ? -45.654 -32.282 -20.110 1.00 106.95 ? 35 LYS C CA 1 ATOM 263 C C . LYS A 1 35 ? -44.477 -31.820 -19.187 1.00 106.95 ? 35 LYS C C 1 ATOM 264 O O . LYS A 1 35 ? -43.989 -32.567 -18.356 1.00 106.95 ? 35 LYS C O 1 ATOM 265 C CB . LYS A 1 35 ? -46.793 -32.727 -19.219 1.00 113.87 ? 35 LYS C CB 1 ATOM 266 C CG . LYS A 1 35 ? -48.083 -32.956 -19.927 1.00 113.87 ? 35 LYS C CG 1 ATOM 267 C CD . LYS A 1 35 ? -49.112 -33.636 -19.010 1.00 113.87 ? 35 LYS C CD 1 ATOM 268 C CE . LYS A 1 35 ? -49.463 -32.820 -17.814 1.00 113.87 ? 35 LYS C CE 1 ATOM 269 N NZ . LYS A 1 35 ? -50.545 -33.424 -17.002 1.00 113.87 ? 35 LYS C NZ 1 ATOM 270 N N . ILE A 1 36 ? -43.943 -30.632 -19.458 1.00 83.94 ? 36 ILE C N 1 ATOM 271 C CA . ILE A 1 36 ? -42.968 -29.969 -18.609 1.00 83.94 ? 36 ILE C CA 1 ATOM 272 C C . ILE A 1 36 ? -43.530 -29.233 -17.374 1.00 83.94 ? 36 ILE C C 1 ATOM 273 O O . ILE A 1 36 ? -43.375 -29.615 -16.224 1.00 83.94 ? 36 ILE C O 1 ATOM 274 C CB . ILE A 1 36 ? -42.059 -28.968 -19.422 1.00 84.46 ? 36 ILE C CB 1 ATOM 275 C CG1 . ILE A 1 36 ? -41.109 -29.722 -20.349 1.00 84.46 ? 36 ILE C CG1 1 ATOM 276 C CG2 . ILE A 1 36 ? -41.340 -28.015 -18.504 1.00 84.46 ? 36 ILE C CG2 1 ATOM 277 C CD1 . ILE A 1 36 ? -40.372 -28.829 -21.337 1.00 84.46 ? 36 ILE C CD1 1 ATOM 278 N N . LEU A 1 37 ? -44.218 -28.142 -17.682 1.00 53.17 ? 37 LEU C N 1 ATOM 279 C CA . LEU A 1 37 ? -44.806 -27.188 -16.733 1.00 53.17 ? 37 LEU C CA 1 ATOM 280 C C . LEU A 1 37 ? -46.202 -26.688 -17.152 1.00 53.17 ? 37 LEU C C 1 ATOM 281 O O . LEU A 1 37 ? -46.449 -26.482 -18.325 1.00 53.17 ? 37 LEU C O 1 ATOM 282 C CB . LEU A 1 37 ? -43.876 -26.003 -16.622 1.00 85.50 ? 37 LEU C CB 1 ATOM 283 C CG . LEU A 1 37 ? -44.302 -24.900 -15.688 1.00 85.50 ? 37 LEU C CG 1 ATOM 284 C CD1 . LEU A 1 37 ? -44.295 -25.497 -14.320 1.00 85.50 ? 37 LEU C CD1 1 ATOM 285 C CD2 . LEU A 1 37 ? -43.349 -23.733 -15.720 1.00 85.50 ? 37 LEU C CD2 1 ATOM 286 N N . GLY A 1 38 ? -47.126 -26.538 -16.225 1.00 115.63 ? 38 GLY C N 1 ATOM 287 C CA . GLY A 1 38 ? -48.454 -26.024 -16.542 1.00 115.63 ? 38 GLY C CA 1 ATOM 288 C C . GLY A 1 38 ? -48.918 -25.368 -15.253 1.00 115.63 ? 38 GLY C C 1 ATOM 289 O O . GLY A 1 38 ? -48.184 -25.441 -14.270 1.00 115.63 ? 38 GLY C O 1 ATOM 290 N N . ASN A 1 39 ? -50.100 -24.760 -15.183 1.00 109.99 ? 39 ASN C N 1 ATOM 291 C CA . ASN A 1 39 ? -50.458 -24.124 -13.910 1.00 109.99 ? 39 ASN C CA 1 ATOM 292 C C . ASN A 1 39 ? -51.918 -24.354 -13.588 1.00 109.99 ? 39 ASN C C 1 ATOM 293 O O . ASN A 1 39 ? -52.669 -24.737 -14.442 1.00 109.99 ? 39 ASN C O 1 ATOM 294 C CB . ASN A 1 39 ? -50.363 -22.619 -13.954 1.00 90.82 ? 39 ASN C CB 1 ATOM 295 C CG . ASN A 1 39 ? -51.528 -22.044 -14.644 1.00 90.82 ? 39 ASN C CG 1 ATOM 296 O OD1 . ASN A 1 39 ? -52.181 -21.133 -14.143 1.00 90.82 ? 39 ASN C OD1 1 ATOM 297 N ND2 . ASN A 1 39 ? -51.827 -22.584 -15.803 1.00 90.82 ? 39 ASN C ND2 1 ATOM 298 N N . GLN A 1 40 ? -52.276 -24.204 -12.322 1.00 68.76 ? 40 GLN C N 1 ATOM 299 C CA . GLN A 1 40 ? -53.647 -24.298 -11.890 1.00 68.76 ? 40 GLN C CA 1 ATOM 300 C C . GLN A 1 40 ? -53.947 -22.914 -11.304 1.00 68.76 ? 40 GLN C C 1 ATOM 301 O O . GLN A 1 40 ? -53.529 -22.634 -10.196 1.00 68.76 ? 40 GLN C O 1 ATOM 302 C CB . GLN A 1 40 ? -53.705 -25.300 -10.749 1.00 92.14 ? 40 GLN C CB 1 ATOM 303 C CG . GLN A 1 40 ? -53.231 -26.637 -11.198 1.00 92.14 ? 40 GLN C CG 1 ATOM 304 C CD . GLN A 1 40 ? -54.062 -27.189 -12.289 1.00 92.14 ? 40 GLN C CD 1 ATOM 305 O OE1 . GLN A 1 40 ? -53.536 -27.618 -13.354 1.00 92.14 ? 40 GLN C OE1 1 ATOM 306 N NE2 . GLN A 1 40 ? -55.404 -27.226 -12.037 1.00 92.14 ? 40 GLN C NE2 1 ATOM 307 N N . GLY A 1 41 ? -54.735 -22.076 -11.961 1.00 166.39 ? 41 GLY C N 1 ATOM 308 C CA . GLY A 1 41 ? -55.018 -20.812 -11.316 1.00 166.39 ? 41 GLY C CA 1 ATOM 309 C C . GLY A 1 41 ? -53.650 -20.314 -10.929 1.00 166.39 ? 41 GLY C C 1 ATOM 310 O O . GLY A 1 41 ? -52.725 -20.262 -11.713 1.00 166.39 ? 41 GLY C O 1 ATOM 311 N N . SER A 1 42 ? -53.570 -19.902 -9.678 1.00 121.49 ? 42 SER C N 1 ATOM 312 C CA . SER A 1 42 ? -52.336 -19.477 -9.040 1.00 121.49 ? 42 SER C CA 1 ATOM 313 C C . SER A 1 42 ? -51.166 -20.451 -8.878 1.00 121.49 ? 42 SER C C 1 ATOM 314 O O . SER A 1 42 ? -50.049 -20.069 -9.120 1.00 121.49 ? 42 SER C O 1 ATOM 315 C CB . SER A 1 42 ? -52.614 -18.870 -7.669 1.00 145.22 ? 42 SER C CB 1 ATOM 316 O OG . SER A 1 42 ? -51.388 -18.450 -7.071 1.00 145.22 ? 42 SER C OG 1 ATOM 317 N N . PHE A 1 43 ? -51.418 -21.715 -8.545 1.00 97.44 ? 43 PHE C N 1 ATOM 318 C CA . PHE A 1 43 ? -50.347 -22.683 -8.231 1.00 97.44 ? 43 PHE C CA 1 ATOM 319 C C . PHE A 1 43 ? -49.695 -23.223 -9.515 1.00 97.44 ? 43 PHE C C 1 ATOM 320 O O . PHE A 1 43 ? -50.258 -23.097 -10.557 1.00 97.44 ? 43 PHE C O 1 ATOM 321 C CB . PHE A 1 43 ? -50.909 -23.833 -7.397 1.00 93.82 ? 43 PHE C CB 1 ATOM 322 C CG . PHE A 1 43 ? -51.483 -23.392 -6.124 1.00 93.82 ? 43 PHE C CG 1 ATOM 323 C CD1 . PHE A 1 43 ? -52.801 -23.048 -6.043 1.00 93.82 ? 43 PHE C CD1 1 ATOM 324 C CD2 . PHE A 1 43 ? -50.692 -23.136 -5.046 1.00 93.82 ? 43 PHE C CD2 1 ATOM 325 C CE1 . PHE A 1 43 ? -53.315 -22.447 -4.900 1.00 93.82 ? 43 PHE C CE1 1 ATOM 326 C CE2 . PHE A 1 43 ? -51.212 -22.515 -3.873 1.00 93.82 ? 43 PHE C CE2 1 ATOM 327 C CZ . PHE A 1 43 ? -52.512 -22.177 -3.812 1.00 93.82 ? 43 PHE C CZ 1 ATOM 328 N N . LEU A 1 44 ? -48.488 -23.769 -9.431 1.00 53.17 ? 44 LEU C N 1 ATOM 329 C CA . LEU A 1 44 ? -47.630 -24.251 -10.528 1.00 53.17 ? 44 LEU C CA 1 ATOM 330 C C . LEU A 1 44 ? -47.306 -25.706 -10.445 1.00 53.17 ? 44 LEU C C 1 ATOM 331 O O . LEU A 1 44 ? -47.301 -26.217 -9.343 1.00 53.17 ? 44 LEU C O 1 ATOM 332 C CB . LEU A 1 44 ? -46.300 -23.553 -10.532 1.00 48.94 ? 44 LEU C CB 1 ATOM 333 C CG . LEU A 1 44 ? -45.350 -23.988 -11.630 1.00 48.94 ? 44 LEU C CG 1 ATOM 334 C CD1 . LEU A 1 44 ? -46.050 -23.682 -12.848 1.00 48.94 ? 44 LEU C CD1 1 ATOM 335 C CD2 . LEU A 1 44 ? -44.013 -23.240 -11.612 1.00 48.94 ? 44 LEU C CD2 1 ATOM 336 N N . THR A 1 45 ? -47.286 -26.446 -11.553 1.00 83.02 ? 45 THR C N 1 ATOM 337 C CA . THR A 1 45 ? -46.858 -27.852 -11.424 1.00 83.02 ? 45 THR C CA 1 ATOM 338 C C . THR A 1 45 ? -45.899 -28.342 -12.507 1.00 83.02 ? 45 THR C C 1 ATOM 339 O O . THR A 1 45 ? -46.004 -27.890 -13.629 1.00 83.02 ? 45 THR C O 1 ATOM 340 C CB . THR A 1 45 ? -48.005 -28.836 -11.460 1.00 106.30 ? 45 THR C CB 1 ATOM 341 O OG1 . THR A 1 45 ? -48.543 -28.872 -12.773 1.00 106.30 ? 45 THR C OG1 1 ATOM 342 C CG2 . THR A 1 45 ? -49.066 -28.421 -10.465 1.00 106.30 ? 45 THR C CG2 1 ATOM 343 N N . LYS A 1 46 ? -45.023 -29.313 -12.186 1.00 79.30 ? 46 LYS C N 1 ATOM 344 C CA . LYS A 1 46 ? -44.040 -29.871 -13.143 1.00 79.30 ? 46 LYS C CA 1 ATOM 345 C C . LYS A 1 46 ? -44.486 -31.223 -13.747 1.00 79.30 ? 46 LYS C C 1 ATOM 346 O O . LYS A 1 46 ? -44.880 -32.159 -13.042 1.00 79.30 ? 46 LYS C O 1 ATOM 347 C CB . LYS A 1 46 ? -42.631 -30.024 -12.459 1.00 80.05 ? 46 LYS C CB 1 ATOM 348 C CG . LYS A 1 46 ? -41.841 -28.734 -12.117 1.00 80.05 ? 46 LYS C CG 1 ATOM 349 C CD . LYS A 1 46 ? -40.501 -29.013 -11.463 1.00 80.05 ? 46 LYS C CD 1 ATOM 350 C CE . LYS A 1 46 ? -40.644 -29.530 -9.984 1.00 80.05 ? 46 LYS C CE 1 ATOM 351 N NZ . LYS A 1 46 ? -39.425 -29.982 -9.159 1.00 80.05 ? 46 LYS C NZ 1 ATOM 352 N N . GLY A 1 47 ? -44.474 -31.279 -15.068 1.00 103.64 ? 47 GLY C N 1 ATOM 353 C CA . GLY A 1 47 ? -44.807 -32.502 -15.769 1.00 103.64 ? 47 GLY C CA 1 ATOM 354 C C . GLY A 1 47 ? -43.786 -33.618 -15.647 1.00 103.64 ? 47 GLY C C 1 ATOM 355 O O . GLY A 1 47 ? -42.613 -33.338 -15.478 1.00 103.64 ? 47 GLY C O 1 ATOM 356 N N . PRO A 1 48 ? -44.187 -34.892 -15.756 1.00 119.61 ? 48 PRO C N 1 ATOM 357 C CA . PRO A 1 48 ? -43.277 -36.049 -15.667 1.00 119.61 ? 48 PRO C CA 1 ATOM 358 C C . PRO A 1 48 ? -42.241 -36.223 -16.805 1.00 119.61 ? 48 PRO C C 1 ATOM 359 O O . PRO A 1 48 ? -41.720 -37.304 -17.033 1.00 119.61 ? 48 PRO C O 1 ATOM 360 C CB . PRO A 1 48 ? -44.248 -37.223 -15.590 1.00 130.90 ? 48 PRO C CB 1 ATOM 361 C CG . PRO A 1 48 ? -45.409 -36.649 -14.812 1.00 130.90 ? 48 PRO C CG 1 ATOM 362 C CD . PRO A 1 48 ? -45.577 -35.296 -15.450 1.00 130.90 ? 48 PRO C CD 1 ATOM 363 N N . SER A 1 49 ? -41.846 -35.131 -17.424 1.00 99.89 ? 49 SER C N 1 ATOM 364 C CA . SER A 1 49 ? -40.907 -35.175 -18.539 1.00 99.89 ? 49 SER C CA 1 ATOM 365 C C . SER A 1 49 ? -39.534 -35.315 -17.911 1.00 99.89 ? 49 SER C C 1 ATOM 366 O O . SER A 1 49 ? -39.408 -35.246 -16.688 1.00 99.89 ? 49 SER C O 1 ATOM 367 C CB . SER A 1 49 ? -40.949 -33.884 -19.372 1.00 113.68 ? 49 SER C CB 1 ATOM 368 O OG . SER A 1 49 ? -40.410 -32.764 -18.679 1.00 113.68 ? 49 SER C OG 1 ATOM 369 N N . LYS A 1 50 ? -38.520 -35.583 -18.737 1.00 127.18 ? 50 LYS C N 1 ATOM 370 C CA . LYS A 1 50 ? -37.131 -35.774 -18.271 1.00 127.18 ? 50 LYS C CA 1 ATOM 371 C C . LYS A 1 50 ? -36.729 -34.485 -17.590 1.00 127.18 ? 50 LYS C C 1 ATOM 372 O O . LYS A 1 50 ? -36.055 -34.500 -16.564 1.00 127.18 ? 50 LYS C O 1 ATOM 373 C CB . LYS A 1 50 ? -36.140 -35.995 -19.406 1.00 95.73 ? 50 LYS C CB 1 ATOM 374 C CG . LYS A 1 50 ? -36.211 -37.309 -20.174 1.00 95.73 ? 50 LYS C CG 1 ATOM 375 C CD . LYS A 1 50 ? -35.107 -37.227 -21.226 1.00 95.73 ? 50 LYS C CD 1 ATOM 376 C CE . LYS A 1 50 ? -35.000 -38.432 -22.098 1.00 95.73 ? 50 LYS C CE 1 ATOM 377 N NZ . LYS A 1 50 ? -33.922 -38.103 -23.071 1.00 95.73 ? 50 LYS C NZ 1 ATOM 378 N N . LEU A 1 51 ? -37.159 -33.391 -18.210 1.00 79.87 ? 51 LEU C N 1 ATOM 379 C CA . LEU A 1 51 ? -36.930 -32.001 -17.822 1.00 79.87 ? 51 LEU C CA 1 ATOM 380 C C . LEU A 1 51 ? -37.432 -31.515 -16.448 1.00 79.87 ? 51 LEU C C 1 ATOM 381 O O . LEU A 1 51 ? -36.759 -30.726 -15.817 1.00 79.87 ? 51 LEU C O 1 ATOM 382 C CB . LEU A 1 51 ? -37.476 -31.019 -18.867 1.00 59.53 ? 51 LEU C CB 1 ATOM 383 C CG . LEU A 1 51 ? -36.786 -31.021 -20.206 1.00 59.53 ? 51 LEU C CG 1 ATOM 384 C CD1 . LEU A 1 51 ? -37.487 -30.054 -21.081 1.00 59.53 ? 51 LEU C CD1 1 ATOM 385 C CD2 . LEU A 1 51 ? -35.329 -30.698 -20.085 1.00 59.53 ? 51 LEU C CD2 1 ATOM 386 N N . ASN A 1 52 ? -38.603 -31.913 -15.989 1.00 102.77 ? 52 ASN C N 1 ATOM 387 C CA . ASN A 1 52 ? -39.157 -31.267 -14.801 1.00 102.77 ? 52 ASN C CA 1 ATOM 388 C C . ASN A 1 52 ? -38.288 -30.391 -13.898 1.00 102.77 ? 52 ASN C C 1 ATOM 389 O O . ASN A 1 52 ? -38.711 -29.255 -13.665 1.00 102.77 ? 52 ASN C O 1 ATOM 390 C CB . ASN A 1 52 ? -39.875 -32.239 -13.864 1.00 94.70 ? 52 ASN C CB 1 ATOM 391 C CG . ASN A 1 52 ? -38.956 -33.188 -13.217 1.00 94.70 ? 52 ASN C CG 1 ATOM 392 O OD1 . ASN A 1 52 ? -39.273 -33.779 -12.182 1.00 94.70 ? 52 ASN C OD1 1 ATOM 393 N ND2 . ASN A 1 52 ? -37.817 -33.407 -13.850 1.00 94.70 ? 52 ASN C ND2 1 ATOM 394 N N . ASP A 1 53 ? -37.148 -30.786 -13.333 1.00 84.10 ? 53 ASP C N 1 ATOM 395 C CA . ASP A 1 53 ? -36.505 -29.690 -12.581 1.00 84.10 ? 53 ASP C CA 1 ATOM 396 C C . ASP A 1 53 ? -35.787 -28.886 -13.675 1.00 84.10 ? 53 ASP C C 1 ATOM 397 O O . ASP A 1 53 ? -35.613 -29.381 -14.770 1.00 84.10 ? 53 ASP C O 1 ATOM 398 C CB . ASP A 1 53 ? -35.508 -30.155 -11.506 1.00 134.06 ? 53 ASP C CB 1 ATOM 399 C CG . ASP A 1 53 ? -34.271 -30.774 -12.081 1.00 134.06 ? 53 ASP C CG 1 ATOM 400 O OD1 . ASP A 1 53 ? -34.298 -31.199 -13.244 1.00 134.06 ? 53 ASP C OD1 1 ATOM 401 O OD2 . ASP A 1 53 ? -33.263 -30.831 -11.356 1.00 134.06 ? 53 ASP C OD2 1 ATOM 402 N N . ARG A 1 54 ? -35.333 -27.682 -13.349 1.00 101.55 ? 54 ARG C N 1 ATOM 403 C CA . ARG A 1 54 ? -34.687 -26.742 -14.281 1.00 101.55 ? 54 ARG C CA 1 ATOM 404 C C . ARG A 1 54 ? -35.698 -26.421 -15.407 1.00 101.55 ? 54 ARG C C 1 ATOM 405 O O . ARG A 1 54 ? -35.295 -25.986 -16.529 1.00 101.55 ? 54 ARG C O 1 ATOM 406 C CB . ARG A 1 54 ? -33.404 -27.302 -14.909 1.00 78.94 ? 54 ARG C CB 1 ATOM 407 C CG . ARG A 1 54 ? -33.559 -28.417 -15.902 1.00 78.94 ? 54 ARG C CG 1 ATOM 408 C CD . ARG A 1 54 ? -32.222 -28.941 -16.424 1.00 78.94 ? 54 ARG C CD 1 ATOM 409 N NE . ARG A 1 54 ? -32.418 -30.006 -17.420 1.00 78.94 ? 54 ARG C NE 1 ATOM 410 C CZ . ARG A 1 54 ? -31.434 -30.641 -18.037 1.00 78.94 ? 54 ARG C CZ 1 ATOM 411 N NH1 . ARG A 1 54 ? -30.196 -30.317 -17.730 1.00 78.94 ? 54 ARG C NH1 1 ATOM 412 N NH2 . ARG A 1 54 ? -31.668 -31.531 -18.991 1.00 78.94 ? 54 ARG C NH2 1 ATOM 413 N N . ALA A 1 55 ? -36.988 -26.675 -15.100 1.00 88.56 ? 55 ALA C N 1 ATOM 414 C CA . ALA A 1 55 ? -38.128 -26.345 -15.951 1.00 88.56 ? 55 ALA C CA 1 ATOM 415 C C . ALA A 1 55 ? -38.880 -25.454 -15.011 1.00 88.56 ? 55 ALA C C 1 ATOM 416 O O . ALA A 1 55 ? -39.372 -25.908 -13.986 1.00 88.56 ? 55 ALA C O 1 ATOM 417 C CB . ALA A 1 55 ? -38.934 -27.566 -16.268 1.00 136.67 ? 55 ALA C CB 1 ATOM 418 N N . ASP A 1 56 ? -39.008 -24.189 -15.329 1.00 80.36 ? 56 ASP C N 1 ATOM 419 C CA . ASP A 1 56 ? -39.712 -23.358 -14.381 1.00 80.36 ? 56 ASP C CA 1 ATOM 420 C C . ASP A 1 56 ? -40.179 -22.105 -15.155 1.00 80.36 ? 56 ASP C C 1 ATOM 421 O O . ASP A 1 56 ? -39.484 -21.660 -16.084 1.00 80.36 ? 56 ASP C O 1 ATOM 422 C CB . ASP A 1 56 ? -38.712 -23.114 -13.227 1.00 110.65 ? 56 ASP C CB 1 ATOM 423 C CG . ASP A 1 56 ? -39.326 -22.474 -12.041 1.00 110.65 ? 56 ASP C CG 1 ATOM 424 O OD1 . ASP A 1 56 ? -40.401 -21.870 -12.219 1.00 110.65 ? 56 ASP C OD1 1 ATOM 425 O OD2 . ASP A 1 56 ? -38.731 -22.590 -10.945 1.00 110.65 ? 56 ASP C OD2 1 ATOM 426 N N . SER A 1 57 ? -41.256 -21.458 -14.728 1.00 82.77 ? 57 SER C N 1 ATOM 427 C CA . SER A 1 57 ? -41.732 -20.320 -15.506 1.00 82.77 ? 57 SER C CA 1 ATOM 428 C C . SER A 1 57 ? -41.952 -19.135 -14.628 1.00 82.77 ? 57 SER C C 1 ATOM 429 O O . SER A 1 57 ? -41.871 -19.283 -13.444 1.00 82.77 ? 57 SER C O 1 ATOM 430 C CB . SER A 1 57 ? -43.012 -20.679 -16.261 1.00 80.98 ? 57 SER C CB 1 ATOM 431 O OG . SER A 1 57 ? -44.113 -20.908 -15.418 1.00 80.98 ? 57 SER C OG 1 ATOM 432 N N . ARG A 1 58 ? -42.191 -17.952 -15.183 1.00 82.74 ? 58 ARG C N 1 ATOM 433 C CA . ARG A 1 58 ? -42.317 -16.776 -14.324 1.00 82.74 ? 58 ARG C CA 1 ATOM 434 C C . ARG A 1 58 ? -43.794 -16.448 -14.002 1.00 82.74 ? 58 ARG C C 1 ATOM 435 O O . ARG A 1 58 ? -44.646 -16.261 -14.832 1.00 82.74 ? 58 ARG C O 1 ATOM 436 C CB . ARG A 1 58 ? -41.735 -15.581 -15.020 1.00 100.74 ? 58 ARG C CB 1 ATOM 437 C CG . ARG A 1 58 ? -40.271 -15.592 -15.190 1.00 100.74 ? 58 ARG C CG 1 ATOM 438 C CD . ARG A 1 58 ? -39.918 -14.336 -15.890 1.00 100.74 ? 58 ARG C CD 1 ATOM 439 N NE . ARG A 1 58 ? -38.506 -14.218 -16.174 1.00 100.74 ? 58 ARG C NE 1 ATOM 440 C CZ . ARG A 1 58 ? -38.018 -13.290 -16.989 1.00 100.74 ? 58 ARG C CZ 1 ATOM 441 N NH1 . ARG A 1 58 ? -38.856 -12.430 -17.544 1.00 100.74 ? 58 ARG C NH1 1 ATOM 442 N NH2 . ARG A 1 58 ? -36.716 -13.251 -17.290 1.00 100.74 ? 58 ARG C NH2 1 ATOM 443 N N . ARG A 1 59 ? -44.051 -16.480 -12.721 1.00 60.49 ? 59 ARG C N 1 ATOM 444 C CA . ARG A 1 59 ? -45.289 -16.291 -12.013 1.00 60.49 ? 59 ARG C CA 1 ATOM 445 C C . ARG A 1 59 ? -46.042 -14.992 -12.122 1.00 60.49 ? 59 ARG C C 1 ATOM 446 O O . ARG A 1 59 ? -47.239 -14.995 -12.258 1.00 60.49 ? 59 ARG C O 1 ATOM 447 C CB . ARG A 1 59 ? -44.931 -16.805 -10.626 1.00 78.92 ? 59 ARG C CB 1 ATOM 448 C CG . ARG A 1 59 ? -44.805 -18.292 -10.919 1.00 78.92 ? 59 ARG C CG 1 ATOM 449 C CD . ARG A 1 59 ? -44.467 -19.228 -9.876 1.00 78.92 ? 59 ARG C CD 1 ATOM 450 N NE . ARG A 1 59 ? -45.483 -19.364 -8.910 1.00 78.92 ? 59 ARG C NE 1 ATOM 451 C CZ . ARG A 1 59 ? -45.350 -20.233 -7.948 1.00 78.92 ? 59 ARG C CZ 1 ATOM 452 N NH1 . ARG A 1 59 ? -44.236 -20.957 -7.925 1.00 78.92 ? 59 ARG C NH1 1 ATOM 453 N NH2 . ARG A 1 59 ? -46.302 -20.389 -7.053 1.00 78.92 ? 59 ARG C NH2 1 ATOM 454 N N . SER A 1 60 ? -45.279 -13.905 -12.119 1.00 106.75 ? 60 SER C N 1 ATOM 455 C CA . SER A 1 60 ? -45.675 -12.491 -12.130 1.00 106.75 ? 60 SER C CA 1 ATOM 456 C C . SER A 1 60 ? -46.499 -12.153 -13.374 1.00 106.75 ? 60 SER C C 1 ATOM 457 O O . SER A 1 60 ? -47.516 -11.476 -13.323 1.00 106.75 ? 60 SER C O 1 ATOM 458 C CB . SER A 1 60 ? -44.446 -11.621 -12.126 1.00 65.49 ? 60 SER C CB 1 ATOM 459 O OG . SER A 1 60 ? -43.680 -11.876 -10.975 1.00 65.49 ? 60 SER C OG 1 ATOM 460 N N . LEU A 1 61 ? -46.056 -12.735 -14.466 1.00 99.91 ? 61 LEU C N 1 ATOM 461 C CA . LEU A 1 61 ? -46.472 -12.648 -15.857 1.00 99.91 ? 61 LEU C CA 1 ATOM 462 C C . LEU A 1 61 ? -47.904 -13.055 -16.177 1.00 99.91 ? 61 LEU C C 1 ATOM 463 O O . LEU A 1 61 ? -48.552 -12.417 -17.017 1.00 99.91 ? 61 LEU C O 1 ATOM 464 C CB . LEU A 1 61 ? -45.540 -13.478 -16.719 1.00 116.99 ? 61 LEU C CB 1 ATOM 465 C CG . LEU A 1 61 ? -44.131 -12.955 -16.889 1.00 116.99 ? 61 LEU C CG 1 ATOM 466 C CD1 . LEU A 1 61 ? -44.196 -11.532 -17.405 1.00 116.99 ? 61 LEU C CD1 1 ATOM 467 C CD2 . LEU A 1 61 ? -43.445 -12.967 -15.550 1.00 116.99 ? 61 LEU C CD2 1 ATOM 468 N N . TRP A 1 62 ? -48.418 -14.070 -15.483 1.00 91.97 ? 62 TRP C N 1 ATOM 469 C CA . TRP A 1 62 ? -49.639 -14.829 -15.770 1.00 91.97 ? 62 TRP C CA 1 ATOM 470 C C . TRP A 1 62 ? -50.812 -13.870 -15.769 1.00 91.97 ? 62 TRP C C 1 ATOM 471 O O . TRP A 1 62 ? -51.666 -14.113 -16.588 1.00 91.97 ? 62 TRP C O 1 ATOM 472 C CB . TRP A 1 62 ? -49.815 -15.941 -14.700 1.00 81.90 ? 62 TRP C CB 1 ATOM 473 C CG . TRP A 1 62 ? -48.674 -17.063 -14.822 1.00 81.90 ? 62 TRP C CG 1 ATOM 474 C CD1 . TRP A 1 62 ? -47.575 -17.007 -15.631 1.00 81.90 ? 62 TRP C CD1 1 ATOM 475 C CD2 . TRP A 1 62 ? -48.506 -18.283 -14.065 1.00 81.90 ? 62 TRP C CD2 1 ATOM 476 N NE1 . TRP A 1 62 ? -46.750 -18.081 -15.414 1.00 81.90 ? 62 TRP C NE1 1 ATOM 477 C CE2 . TRP A 1 62 ? -47.301 -18.875 -14.464 1.00 81.90 ? 62 TRP C CE2 1 ATOM 478 C CE3 . TRP A 1 62 ? -49.253 -18.925 -13.104 1.00 81.90 ? 62 TRP C CE3 1 ATOM 479 C CZ2 . TRP A 1 62 ? -46.844 -20.049 -13.942 1.00 81.90 ? 62 TRP C CZ2 1 ATOM 480 C CZ3 . TRP A 1 62 ? -48.780 -20.107 -12.587 1.00 81.90 ? 62 TRP C CZ3 1 ATOM 481 C CH2 . TRP A 1 62 ? -47.598 -20.649 -13.006 1.00 81.90 ? 62 TRP C CH2 1 ATOM 482 N N . ASP A 1 63 ? -50.924 -12.845 -14.911 1.00 143.21 ? 63 ASP C N 1 ATOM 483 C CA . ASP A 1 63 ? -52.100 -11.918 -14.995 1.00 143.21 ? 63 ASP C CA 1 ATOM 484 C C . ASP A 1 63 ? -52.216 -11.181 -16.369 1.00 143.21 ? 63 ASP C C 1 ATOM 485 O O . ASP A 1 63 ? -53.332 -10.939 -16.854 1.00 143.21 ? 63 ASP C O 1 ATOM 486 C CB . ASP A 1 63 ? -51.895 -10.796 -14.007 1.00 118.90 ? 63 ASP C CB 1 ATOM 487 C CG . ASP A 1 63 ? -52.015 -11.256 -12.616 1.00 118.90 ? 63 ASP C CG 1 ATOM 488 O OD1 . ASP A 1 63 ? -52.624 -12.332 -12.422 1.00 118.90 ? 63 ASP C OD1 1 ATOM 489 O OD2 . ASP A 1 63 ? -51.472 -10.558 -11.723 1.00 118.90 ? 63 ASP C OD2 1 ATOM 490 N N . GLN A 1 64 ? -51.083 -10.750 -16.930 1.00 108.16 ? 64 GLN C N 1 ATOM 491 C CA . GLN A 1 64 ? -50.940 -10.282 -18.316 1.00 108.16 ? 64 GLN C CA 1 ATOM 492 C C . GLN A 1 64 ? -51.301 -11.328 -19.353 1.00 108.16 ? 64 GLN C C 1 ATOM 493 O O . GLN A 1 64 ? -51.740 -11.040 -20.468 1.00 108.16 ? 64 GLN C O 1 ATOM 494 C CB . GLN A 1 64 ? -49.760 -9.347 -18.576 1.00 134.92 ? 64 GLN C CB 1 ATOM 495 C CG . GLN A 1 64 ? -50.211 -7.954 -18.081 1.00 134.92 ? 64 GLN C CG 1 ATOM 496 C CD . GLN A 1 64 ? -50.341 -7.830 -16.581 1.00 134.92 ? 64 GLN C CD 1 ATOM 497 O OE1 . GLN A 1 64 ? -49.343 -7.838 -15.868 1.00 134.92 ? 64 GLN C OE1 1 ATOM 498 N NE2 . GLN A 1 64 ? -51.591 -7.774 -16.086 1.00 134.92 ? 64 GLN C NE2 1 ATOM 499 N N . GLY A 1 65 ? -50.877 -12.541 -19.031 1.00 122.61 ? 65 GLY C N 1 ATOM 500 C CA . GLY A 1 65 ? -51.204 -13.682 -19.852 1.00 122.61 ? 65 GLY C CA 1 ATOM 501 C C . GLY A 1 65 ? -50.021 -14.203 -20.573 1.00 122.61 ? 65 GLY C C 1 ATOM 502 O O . GLY A 1 65 ? -50.129 -14.788 -21.623 1.00 122.61 ? 65 GLY C O 1 ATOM 503 N N . ASN A 1 66 ? -48.873 -13.944 -19.975 1.00 102.50 ? 66 ASN C N 1 ATOM 504 C CA . ASN A 1 66 ? -47.582 -14.391 -20.476 1.00 102.50 ? 66 ASN C CA 1 ATOM 505 C C . ASN A 1 66 ? -47.186 -15.642 -19.661 1.00 102.50 ? 66 ASN C C 1 ATOM 506 O O . ASN A 1 66 ? -47.043 -15.574 -18.445 1.00 102.50 ? 66 ASN C O 1 ATOM 507 C CB . ASN A 1 66 ? -46.561 -13.264 -20.367 1.00 106.28 ? 66 ASN C CB 1 ATOM 508 C CG . ASN A 1 66 ? -45.255 -13.651 -20.951 1.00 106.28 ? 66 ASN C CG 1 ATOM 509 O OD1 . ASN A 1 66 ? -44.962 -14.842 -21.109 1.00 106.28 ? 66 ASN C OD1 1 ATOM 510 N ND2 . ASN A 1 66 ? -44.462 -12.662 -21.326 1.00 106.28 ? 66 ASN C ND2 1 ATOM 511 N N . PHE A 1 67 ? -46.999 -16.778 -20.326 1.00 87.07 ? 67 PHE C N 1 ATOM 512 C CA . PHE A 1 67 ? -46.753 -18.039 -19.622 1.00 87.07 ? 67 PHE C CA 1 ATOM 513 C C . PHE A 1 67 ? -45.502 -18.671 -20.273 1.00 87.07 ? 67 PHE C C 1 ATOM 514 O O . PHE A 1 67 ? -45.599 -19.617 -21.057 1.00 87.07 ? 67 PHE C O 1 ATOM 515 C CB . PHE A 1 67 ? -47.941 -18.969 -19.891 1.00 76.38 ? 67 PHE C CB 1 ATOM 516 C CG . PHE A 1 67 ? -49.255 -18.332 -19.641 1.00 76.38 ? 67 PHE C CG 1 ATOM 517 C CD1 . PHE A 1 67 ? -50.290 -18.525 -20.544 1.00 76.38 ? 67 PHE C CD1 1 ATOM 518 C CD2 . PHE A 1 67 ? -49.448 -17.454 -18.588 1.00 76.38 ? 67 PHE C CD2 1 ATOM 519 C CE1 . PHE A 1 67 ? -51.495 -17.855 -20.417 1.00 76.38 ? 67 PHE C CE1 1 ATOM 520 C CE2 . PHE A 1 67 ? -50.658 -16.776 -18.451 1.00 76.38 ? 67 PHE C CE2 1 ATOM 521 C CZ . PHE A 1 67 ? -51.676 -16.987 -19.378 1.00 76.38 ? 67 PHE C CZ 1 ATOM 522 N N . PRO A 1 68 ? -44.317 -18.185 -19.915 1.00 89.18 ? 68 PRO C N 1 ATOM 523 C CA . PRO A 1 68 ? -43.042 -18.658 -20.438 1.00 89.18 ? 68 PRO C CA 1 ATOM 524 C C . PRO A 1 68 ? -42.567 -20.000 -19.933 1.00 89.18 ? 68 PRO C C 1 ATOM 525 O O . PRO A 1 68 ? -43.032 -20.492 -18.944 1.00 89.18 ? 68 PRO C O 1 ATOM 526 C CB . PRO A 1 68 ? -42.072 -17.554 -20.043 1.00 59.50 ? 68 PRO C CB 1 ATOM 527 C CG . PRO A 1 68 ? -42.948 -16.518 -19.263 1.00 59.50 ? 68 PRO C CG 1 ATOM 528 C CD . PRO A 1 68 ? -44.100 -17.276 -18.793 1.00 59.50 ? 68 PRO C CD 1 ATOM 529 N N . LEU A 1 69 ? -41.682 -20.616 -20.685 1.00 71.68 ? 69 LEU C N 1 ATOM 530 C CA . LEU A 1 69 ? -41.069 -21.847 -20.291 1.00 71.68 ? 69 LEU C CA 1 ATOM 531 C C . LEU A 1 69 ? -39.634 -21.487 -20.258 1.00 71.68 ? 69 LEU C C 1 ATOM 532 O O . LEU A 1 69 ? -39.186 -20.830 -21.175 1.00 71.68 ? 69 LEU C O 1 ATOM 533 C CB . LEU A 1 69 ? -41.263 -22.957 -21.295 1.00 65.71 ? 69 LEU C CB 1 ATOM 534 C CG . LEU A 1 69 ? -40.516 -24.179 -20.757 1.00 65.71 ? 69 LEU C CG 1 ATOM 535 C CD1 . LEU A 1 69 ? -41.058 -24.623 -19.398 1.00 65.71 ? 69 LEU C CD1 1 ATOM 536 C CD2 . LEU A 1 69 ? -40.558 -25.303 -21.780 1.00 65.71 ? 69 LEU C CD2 1 ATOM 537 N N . ILE A 1 70 ? -38.948 -21.809 -19.162 1.00 66.61 ? 70 ILE C N 1 ATOM 538 C CA . ILE A 1 70 ? -37.534 -21.584 -18.997 1.00 66.61 ? 70 ILE C CA 1 ATOM 539 C C . ILE A 1 70 ? -36.806 -22.872 -18.759 1.00 66.61 ? 70 ILE C C 1 ATOM 540 O O . ILE A 1 70 ? -37.119 -23.614 -17.869 1.00 66.61 ? 70 ILE C O 1 ATOM 541 C CB . ILE A 1 70 ? -37.250 -20.691 -17.820 1.00 50.55 ? 70 ILE C CB 1 ATOM 542 C CG1 . ILE A 1 70 ? -37.908 -19.356 -17.998 1.00 50.55 ? 70 ILE C CG1 1 ATOM 543 C CG2 . ILE A 1 70 ? -35.755 -20.617 -17.594 1.00 50.55 ? 70 ILE C CG2 1 ATOM 544 C CD1 . ILE A 1 70 ? -37.851 -18.528 -16.761 1.00 50.55 ? 70 ILE C CD1 1 ATOM 545 N N . ILE A 1 71 ? -35.840 -23.152 -19.572 1.00 84.64 ? 71 ILE C N 1 ATOM 546 C CA . ILE A 1 71 ? -34.988 -24.274 -19.364 1.00 84.64 ? 71 ILE C CA 1 ATOM 547 C C . ILE A 1 71 ? -33.697 -23.662 -19.041 1.00 84.64 ? 71 ILE C C 1 ATOM 548 O O . ILE A 1 71 ? -33.211 -22.790 -19.784 1.00 84.64 ? 71 ILE C O 1 ATOM 549 C CB . ILE A 1 71 ? -34.877 -25.302 -20.496 1.00 73.80 ? 71 ILE C CB 1 ATOM 550 C CG1 . ILE A 1 71 ? -36.234 -25.880 -20.777 1.00 73.80 ? 71 ILE C CG1 1 ATOM 551 C CG2 . ILE A 1 71 ? -33.799 -26.310 -20.226 1.00 73.80 ? 71 ILE C CG2 1 ATOM 552 C CD1 . ILE A 1 71 ? -36.241 -26.692 -21.980 1.00 73.80 ? 71 ILE C CD1 1 ATOM 553 N N . LYS A 1 72 ? -33.120 -24.135 -17.954 1.00 90.75 ? 72 LYS C N 1 ATOM 554 C CA . LYS A 1 72 ? -31.879 -23.590 -17.446 1.00 90.75 ? 72 LYS C CA 1 ATOM 555 C C . LYS A 1 72 ? -30.877 -24.740 -17.223 1.00 90.75 ? 72 LYS C C 1 ATOM 556 O O . LYS A 1 72 ? -31.305 -25.921 -17.046 1.00 90.75 ? 72 LYS C O 1 ATOM 557 C CB . LYS A 1 72 ? -32.282 -22.738 -16.222 1.00 62.08 ? 72 LYS C CB 1 ATOM 558 C CG . LYS A 1 72 ? -33.023 -23.526 -15.154 1.00 62.08 ? 72 LYS C CG 1 ATOM 559 C CD . LYS A 1 72 ? -33.463 -22.695 -13.939 1.00 62.08 ? 72 LYS C CD 1 ATOM 560 C CE . LYS A 1 72 ? -34.195 -23.610 -12.946 1.00 62.08 ? 72 LYS C CE 1 ATOM 561 N NZ . LYS A 1 72 ? -35.335 -22.894 -12.185 1.00 62.08 ? 72 LYS C NZ 1 ATOM 562 N N . ASN A 1 73 ? -29.555 -24.389 -17.244 1.00 93.10 ? 73 ASN C N 1 ATOM 563 C CA . ASN A 1 73 ? -28.497 -25.415 -17.220 1.00 93.10 ? 73 ASN C CA 1 ATOM 564 C C . ASN A 1 73 ? -28.718 -26.265 -18.456 1.00 93.10 ? 73 ASN C C 1 ATOM 565 O O . ASN A 1 73 ? -28.811 -27.489 -18.391 1.00 93.10 ? 73 ASN C O 1 ATOM 566 C CB . ASN A 1 73 ? -28.601 -26.304 -15.984 1.00 104.23 ? 73 ASN C CB 1 ATOM 567 C CG . ASN A 1 73 ? -27.426 -27.177 -15.820 1.00 104.23 ? 73 ASN C CG 1 ATOM 568 O OD1 . ASN A 1 73 ? -27.471 -28.135 -15.041 1.00 104.23 ? 73 ASN C OD1 1 ATOM 569 N ND2 . ASN A 1 73 ? -26.360 -26.879 -16.559 1.00 104.23 ? 73 ASN C ND2 1 ATOM 570 N N . LEU A 1 74 ? -28.824 -25.582 -19.593 1.00 92.30 ? 74 LEU C N 1 ATOM 571 C CA . LEU A 1 74 ? -29.120 -26.253 -20.860 1.00 92.30 ? 74 LEU C CA 1 ATOM 572 C C . LEU A 1 74 ? -28.147 -27.297 -21.328 1.00 92.30 ? 74 LEU C C 1 ATOM 573 O O . LEU A 1 74 ? -26.921 -27.219 -21.168 1.00 92.30 ? 74 LEU C O 1 ATOM 574 C CB . LEU A 1 74 ? -29.256 -25.293 -22.063 1.00 56.58 ? 74 LEU C CB 1 ATOM 575 C CG . LEU A 1 74 ? -30.456 -24.373 -22.138 1.00 56.58 ? 74 LEU C CG 1 ATOM 576 C CD1 . LEU A 1 74 ? -30.242 -23.402 -23.254 1.00 56.58 ? 74 LEU C CD1 1 ATOM 577 C CD2 . LEU A 1 74 ? -31.735 -25.166 -22.273 1.00 56.58 ? 74 LEU C CD2 1 ATOM 578 N N . LYS A 1 75 ? -28.775 -28.336 -21.855 1.00 89.61 ? 75 LYS C N 1 ATOM 579 C CA . LYS A 1 75 ? -28.130 -29.501 -22.424 1.00 89.61 ? 75 LYS C CA 1 ATOM 580 C C . LYS A 1 75 ? -28.438 -29.710 -23.915 1.00 89.61 ? 75 LYS C C 1 ATOM 581 O O . LYS A 1 75 ? -29.452 -29.250 -24.446 1.00 89.61 ? 75 LYS C O 1 ATOM 582 C CB . LYS A 1 75 ? -28.420 -30.792 -21.640 1.00 90.57 ? 75 LYS C CB 1 ATOM 583 C CG . LYS A 1 75 ? -27.806 -30.906 -20.283 1.00 90.57 ? 75 LYS C CG 1 ATOM 584 C CD . LYS A 1 75 ? -28.222 -32.240 -19.708 1.00 90.57 ? 75 LYS C CD 1 ATOM 585 C CE . LYS A 1 75 ? -27.650 -32.463 -18.321 1.00 90.57 ? 75 LYS C CE 1 ATOM 586 N NZ . LYS A 1 75 ? -27.985 -33.810 -17.773 1.00 90.57 ? 75 LYS C NZ 1 ATOM 587 N N . ILE A 1 76 ? -27.505 -30.367 -24.590 1.00 79.87 ? 76 ILE C N 1 ATOM 588 C CA . ILE A 1 76 ? -27.613 -30.610 -26.006 1.00 79.87 ? 76 ILE C CA 1 ATOM 589 C C . ILE A 1 76 ? -28.855 -31.416 -26.313 1.00 79.87 ? 76 ILE C C 1 ATOM 590 O O . ILE A 1 76 ? -29.610 -31.036 -27.184 1.00 79.87 ? 76 ILE C O 1 ATOM 591 C CB . ILE A 1 76 ? -26.485 -31.470 -26.492 1.00 115.39 ? 76 ILE C CB 1 ATOM 592 C CG1 . ILE A 1 76 ? -25.116 -30.816 -26.239 1.00 115.39 ? 76 ILE C CG1 1 ATOM 593 C CG2 . ILE A 1 76 ? -26.714 -31.719 -27.952 1.00 115.39 ? 76 ILE C CG2 1 ATOM 594 C CD1 . ILE A 1 76 ? -24.954 -29.430 -26.786 1.00 115.39 ? 76 ILE C CD1 1 ATOM 595 N N . GLU A 1 77 ? -29.106 -32.454 -25.516 1.00 92.57 ? 77 GLU C N 1 ATOM 596 C CA . GLU A 1 77 ? -30.225 -33.400 -25.714 1.00 92.57 ? 77 GLU C CA 1 ATOM 597 C C . GLU A 1 77 ? -31.581 -32.684 -25.467 1.00 92.57 ? 77 GLU C C 1 ATOM 598 O O . GLU A 1 77 ? -32.655 -33.109 -25.921 1.00 92.57 ? 77 GLU C O 1 ATOM 599 C CB . GLU A 1 77 ? -30.121 -34.636 -24.810 1.00 107.05 ? 77 GLU C CB 1 ATOM 600 C CG . GLU A 1 77 ? -30.356 -34.370 -23.344 1.00 107.05 ? 77 GLU C CG 1 ATOM 601 C CD . GLU A 1 77 ? -30.241 -35.614 -22.512 1.00 107.05 ? 77 GLU C CD 1 ATOM 602 O OE1 . GLU A 1 77 ? -31.125 -36.481 -22.666 1.00 107.05 ? 77 GLU C OE1 1 ATOM 603 O OE2 . GLU A 1 77 ? -29.294 -35.701 -21.695 1.00 107.05 ? 77 GLU C OE2 1 ATOM 604 N N . ASP A 1 78 ? -31.507 -31.570 -24.770 1.00 98.03 ? 78 ASP C N 1 ATOM 605 C CA . ASP A 1 78 ? -32.672 -30.770 -24.476 1.00 98.03 ? 78 ASP C CA 1 ATOM 606 C C . ASP A 1 78 ? -33.218 -30.080 -25.731 1.00 98.03 ? 78 ASP C C 1 ATOM 607 O O . ASP A 1 78 ? -34.366 -29.640 -25.733 1.00 98.03 ? 78 ASP C O 1 ATOM 608 C CB . ASP A 1 78 ? -32.475 -29.761 -23.316 1.00 111.13 ? 78 ASP C CB 1 ATOM 609 C CG . ASP A 1 78 ? -32.353 -30.438 -21.930 1.00 111.13 ? 78 ASP C CG 1 ATOM 610 O OD1 . ASP A 1 78 ? -32.798 -31.605 -21.823 1.00 111.13 ? 78 ASP C OD1 1 ATOM 611 O OD2 . ASP A 1 78 ? -31.853 -29.804 -20.951 1.00 111.13 ? 78 ASP C OD2 1 ATOM 612 N N . SER A 1 79 ? -32.419 -29.931 -26.789 1.00 162.25 ? 79 SER C N 1 ATOM 613 C CA . SER A 1 79 ? -32.916 -29.227 -27.983 1.00 162.25 ? 79 SER C CA 1 ATOM 614 C C . SER A 1 79 ? -34.112 -30.059 -28.414 1.00 162.25 ? 79 SER C C 1 ATOM 615 O O . SER A 1 79 ? -34.082 -31.285 -28.477 1.00 162.25 ? 79 SER C O 1 ATOM 616 C CB . SER A 1 79 ? -31.898 -29.371 -29.088 1.00 78.62 ? 79 SER C CB 1 ATOM 617 O OG . SER A 1 79 ? -30.750 -28.620 -28.779 1.00 78.62 ? 79 SER C OG 1 ATOM 618 N N . ASP A 1 80 ? -35.186 -29.343 -28.663 1.00 116.86 ? 80 ASP C N 1 ATOM 619 C CA . ASP A 1 80 ? -36.461 -29.952 -28.975 1.00 116.86 ? 80 ASP C CA 1 ATOM 620 C C . ASP A 1 80 ? -37.324 -28.897 -29.684 1.00 116.86 ? 80 ASP C C 1 ATOM 621 O O . ASP A 1 80 ? -36.894 -27.740 -29.796 1.00 116.86 ? 80 ASP C O 1 ATOM 622 C CB . ASP A 1 80 ? -37.122 -30.464 -27.678 1.00 122.40 ? 80 ASP C CB 1 ATOM 623 C CG . ASP A 1 80 ? -38.204 -31.524 -27.927 1.00 122.40 ? 80 ASP C CG 1 ATOM 624 O OD1 . ASP A 1 80 ? -38.724 -31.652 -29.058 1.00 122.40 ? 80 ASP C OD1 1 ATOM 625 O OD2 . ASP A 1 80 ? -38.534 -32.237 -26.959 1.00 122.40 ? 80 ASP C OD2 1 ATOM 626 N N . THR A 1 81 ? -38.471 -29.312 -30.240 1.00 82.19 ? 81 THR C N 1 ATOM 627 C CA . THR A 1 81 ? -39.445 -28.400 -30.860 1.00 82.19 ? 81 THR C CA 1 ATOM 628 C C . THR A 1 81 ? -40.424 -28.344 -29.657 1.00 82.19 ? 81 THR C C 1 ATOM 629 O O . THR A 1 81 ? -40.884 -29.396 -29.252 1.00 82.19 ? 81 THR C O 1 ATOM 630 C CB . THR A 1 81 ? -40.171 -29.118 -32.024 1.00 91.94 ? 81 THR C CB 1 ATOM 631 O OG1 . THR A 1 81 ? -39.208 -29.737 -32.908 1.00 91.94 ? 81 THR C OG1 1 ATOM 632 C CG2 . THR A 1 81 ? -41.006 -28.104 -32.821 1.00 91.94 ? 81 THR C CG2 1 ATOM 633 N N . TYR A 1 82 ? -40.746 -27.173 -29.078 1.00 120.96 ? 82 TYR C N 1 ATOM 634 C CA . TYR A 1 82 ? -41.655 -27.176 -27.891 1.00 120.96 ? 82 TYR C CA 1 ATOM 635 C C . TYR A 1 82 ? -42.910 -26.373 -28.159 1.00 120.96 ? 82 TYR C C 1 ATOM 636 O O . TYR A 1 82 ? -42.865 -25.307 -28.778 1.00 120.96 ? 82 TYR C O 1 ATOM 637 C CB . TYR A 1 82 ? -41.006 -26.471 -26.665 1.00 113.42 ? 82 TYR C CB 1 ATOM 638 C CG . TYR A 1 82 ? -39.837 -27.156 -25.969 1.00 113.42 ? 82 TYR C CG 1 ATOM 639 C CD1 . TYR A 1 82 ? -38.523 -26.922 -26.362 1.00 113.42 ? 82 TYR C CD1 1 ATOM 640 C CD2 . TYR A 1 82 ? -40.050 -28.017 -24.886 1.00 113.42 ? 82 TYR C CD2 1 ATOM 641 C CE1 . TYR A 1 82 ? -37.463 -27.543 -25.721 1.00 113.42 ? 82 TYR C CE1 1 ATOM 642 C CE2 . TYR A 1 82 ? -39.005 -28.629 -24.234 1.00 113.42 ? 82 TYR C CE2 1 ATOM 643 C CZ . TYR A 1 82 ? -37.722 -28.394 -24.666 1.00 113.42 ? 82 TYR C CZ 1 ATOM 644 O OH . TYR A 1 82 ? -36.690 -29.052 -24.072 1.00 113.42 ? 82 TYR C OH 1 ATOM 645 N N . ILE A 1 83 ? -44.030 -26.925 -27.666 1.00 88.53 ? 83 ILE C N 1 ATOM 646 C CA . ILE A 1 83 ? -45.356 -26.359 -27.802 1.00 88.53 ? 83 ILE C CA 1 ATOM 647 C C . ILE A 1 83 ? -46.167 -25.989 -26.585 1.00 88.53 ? 83 ILE C C 1 ATOM 648 O O . ILE A 1 83 ? -46.466 -26.850 -25.772 1.00 88.53 ? 83 ILE C O 1 ATOM 649 C CB . ILE A 1 83 ? -46.157 -27.156 -28.837 1.00 144.60 ? 83 ILE C CB 1 ATOM 650 C CG1 . ILE A 1 83 ? -45.408 -27.079 -30.186 1.00 144.60 ? 83 ILE C CG1 1 ATOM 651 C CG2 . ILE A 1 83 ? -47.567 -26.671 -28.892 1.00 144.60 ? 83 ILE C CG2 1 ATOM 652 C CD1 . ILE A 1 83 ? -45.893 -27.988 -31.318 1.00 144.60 ? 83 ILE C CD1 1 ATOM 653 N N . CYS A 1 84 ? -46.521 -24.707 -26.481 1.00 149.40 ? 84 CYS C N 1 ATOM 654 C CA . CYS A 1 84 ? -47.301 -24.154 -25.367 1.00 149.40 ? 84 CYS C CA 1 ATOM 655 C C . CYS A 1 84 ? -48.777 -23.982 -25.758 1.00 149.40 ? 84 CYS C C 1 ATOM 656 O O . CYS A 1 84 ? -49.055 -23.442 -26.826 1.00 149.40 ? 84 CYS C O 1 ATOM 657 C CB . CYS A 1 84 ? -46.677 -22.814 -24.937 1.00 89.91 ? 84 CYS C CB 1 ATOM 658 S SG . CYS A 1 84 ? -47.806 -21.654 -24.121 1.00 89.91 ? 84 CYS C SG 1 ATOM 659 N N . GLU A 1 85 ? -49.706 -24.481 -24.924 1.00 68.81 ? 85 GLU C N 1 ATOM 660 C CA . GLU A 1 85 ? -51.167 -24.429 -25.179 1.00 68.81 ? 85 GLU C CA 1 ATOM 661 C C . GLU A 1 85 ? -52.004 -23.497 -24.284 1.00 68.81 ? 85 GLU C C 1 ATOM 662 O O . GLU A 1 85 ? -52.224 -23.815 -23.146 1.00 68.81 ? 85 GLU C O 1 ATOM 663 C CB . GLU A 1 85 ? -51.601 -25.850 -24.947 1.00 93.89 ? 85 GLU C CB 1 ATOM 664 C CG . GLU A 1 85 ? -51.094 -26.743 -26.029 1.00 93.89 ? 85 GLU C CG 1 ATOM 665 C CD . GLU A 1 85 ? -51.353 -28.164 -25.724 1.00 93.89 ? 85 GLU C CD 1 ATOM 666 O OE1 . GLU A 1 85 ? -51.895 -28.408 -24.642 1.00 93.89 ? 85 GLU C OE1 1 ATOM 667 O OE2 . GLU A 1 85 ? -51.028 -29.036 -26.548 1.00 93.89 ? 85 GLU C OE2 1 ATOM 668 N N . VAL A 1 86 ? -52.631 -22.477 -24.857 1.00 144.27 ? 86 VAL C N 1 ATOM 669 C CA . VAL A 1 86 ? -53.449 -21.547 -24.082 1.00 144.27 ? 86 VAL C CA 1 ATOM 670 C C . VAL A 1 86 ? -54.737 -21.274 -24.842 1.00 144.27 ? 86 VAL C C 1 ATOM 671 O O . VAL A 1 86 ? -54.719 -21.178 -26.067 1.00 144.27 ? 86 VAL C O 1 ATOM 672 C CB . VAL A 1 86 ? -52.630 -20.179 -23.772 1.00 82.42 ? 86 VAL C CB 1 ATOM 673 C CG1 . VAL A 1 86 ? -52.215 -19.480 -25.017 1.00 82.42 ? 86 VAL C CG1 1 ATOM 674 C CG2 . VAL A 1 86 ? -53.473 -19.189 -22.983 1.00 82.42 ? 86 VAL C CG2 1 ATOM 675 N N . GLU A 1 87 ? -55.865 -21.197 -24.138 1.00 145.39 ? 87 GLU C N 1 ATOM 676 C CA . GLU A 1 87 ? -57.115 -20.854 -24.807 1.00 145.39 ? 87 GLU C CA 1 ATOM 677 C C . GLU A 1 87 ? -57.260 -21.525 -26.192 1.00 145.39 ? 87 GLU C C 1 ATOM 678 O O . GLU A 1 87 ? -57.622 -20.881 -27.179 1.00 145.39 ? 87 GLU C O 1 ATOM 679 C CB . GLU A 1 87 ? -57.163 -19.300 -24.793 1.00 131.97 ? 87 GLU C CB 1 ATOM 680 C CG . GLU A 1 87 ? -56.232 -18.575 -25.798 1.00 131.97 ? 87 GLU C CG 1 ATOM 681 C CD . GLU A 1 87 ? -56.305 -17.033 -25.757 1.00 131.97 ? 87 GLU C CD 1 ATOM 682 O OE1 . GLU A 1 87 ? -55.445 -16.397 -26.405 1.00 131.97 ? 87 GLU C OE1 1 ATOM 683 O OE2 . GLU A 1 87 ? -57.186 -16.448 -25.090 1.00 131.97 ? 87 GLU C OE2 1 ATOM 684 N N . ASP A 1 88 ? -57.035 -22.844 -26.222 1.00 180.67 ? 88 ASP C N 1 ATOM 685 C CA . ASP A 1 88 ? -57.104 -23.687 -27.436 1.00 180.67 ? 88 ASP C CA 1 ATOM 686 C C . ASP A 1 88 ? -56.240 -23.249 -28.648 1.00 180.67 ? 88 ASP C C 1 ATOM 687 O O . ASP A 1 88 ? -56.672 -23.366 -29.797 1.00 180.67 ? 88 ASP C O 1 ATOM 688 C CB . ASP A 1 88 ? -58.563 -23.801 -27.885 1.00 180.57 ? 88 ASP C CB 1 ATOM 689 C CG . ASP A 1 88 ? -59.412 -24.637 -26.942 1.00 180.57 ? 88 ASP C CG 1 ATOM 690 O OD1 . ASP A 1 88 ? -58.858 -25.458 -26.172 1.00 180.57 ? 88 ASP C OD1 1 ATOM 691 O OD2 . ASP A 1 88 ? -60.648 -24.444 -26.964 1.00 180.57 ? 88 ASP C OD2 1 ATOM 692 N N . GLN A 1 89 ? -55.017 -22.786 -28.405 1.00 85.99 ? 89 GLN C N 1 ATOM 693 C CA . GLN A 1 89 ? -54.162 -22.324 -29.501 1.00 85.99 ? 89 GLN C CA 1 ATOM 694 C C . GLN A 1 89 ? -52.888 -23.149 -29.539 1.00 85.99 ? 89 GLN C C 1 ATOM 695 O O . GLN A 1 89 ? -52.383 -23.467 -28.513 1.00 85.99 ? 89 GLN C O 1 ATOM 696 C CB . GLN A 1 89 ? -53.685 -20.875 -29.246 1.00 113.05 ? 89 GLN C CB 1 ATOM 697 C CG . GLN A 1 89 ? -54.714 -19.723 -29.326 1.00 113.05 ? 89 GLN C CG 1 ATOM 698 C CD . GLN A 1 89 ? -54.068 -18.348 -29.044 1.00 113.05 ? 89 GLN C CD 1 ATOM 699 O OE1 . GLN A 1 89 ? -52.989 -18.246 -28.448 1.00 113.05 ? 89 GLN C OE1 1 ATOM 700 N NE2 . GLN A 1 89 ? -54.758 -17.289 -29.454 1.00 113.05 ? 89 GLN C NE2 1 ATOM 701 N N . LYS A 1 90 ? -52.342 -23.545 -30.666 1.00 137.03 ? 90 LYS C N 1 ATOM 702 C CA . LYS A 1 90 ? -51.046 -24.182 -30.481 1.00 137.03 ? 90 LYS C CA 1 ATOM 703 C C . LYS A 1 90 ? -49.961 -23.236 -30.967 1.00 137.03 ? 90 LYS C C 1 ATOM 704 O O . LYS A 1 90 ? -49.964 -22.823 -32.120 1.00 137.03 ? 90 LYS C O 1 ATOM 705 C CB . LYS A 1 90 ? -50.969 -25.502 -31.221 1.00 71.34 ? 90 LYS C CB 1 ATOM 706 C CG . LYS A 1 90 ? -52.017 -26.430 -30.723 1.00 71.34 ? 90 LYS C CG 1 ATOM 707 C CD . LYS A 1 90 ? -51.663 -26.849 -29.347 1.00 71.34 ? 90 LYS C CD 1 ATOM 708 C CE . LYS A 1 90 ? -52.701 -27.789 -28.809 1.00 71.34 ? 90 LYS C CE 1 ATOM 709 N NZ . LYS A 1 90 ? -52.747 -28.885 -29.790 1.00 71.34 ? 90 LYS C NZ 1 ATOM 710 N N . GLU A 1 91 ? -48.990 -22.946 -30.112 1.00 109.83 ? 91 GLU C N 1 ATOM 711 C CA . GLU A 1 91 ? -47.913 -22.054 -30.499 1.00 109.83 ? 91 GLU C CA 1 ATOM 712 C C . GLU A 1 91 ? -46.675 -22.931 -30.344 1.00 109.83 ? 91 GLU C C 1 ATOM 713 O O . GLU A 1 91 ? -46.547 -23.669 -29.369 1.00 109.83 ? 91 GLU C O 1 ATOM 714 C CB . GLU A 1 91 ? -47.948 -20.847 -29.580 1.00 152.69 ? 91 GLU C CB 1 ATOM 715 C CG . GLU A 1 91 ? -49.191 -20.051 -29.944 1.00 152.69 ? 91 GLU C CG 1 ATOM 716 C CD . GLU A 1 91 ? -49.448 -18.832 -29.094 1.00 152.69 ? 91 GLU C CD 1 ATOM 717 O OE1 . GLU A 1 91 ? -48.604 -18.535 -28.214 1.00 152.69 ? 91 GLU C OE1 1 ATOM 718 O OE2 . GLU A 1 91 ? -50.540 -18.209 -29.272 1.00 152.69 ? 91 GLU C OE2 1 ATOM 719 N N . GLU A 1 92 ? -45.732 -22.823 -31.266 1.00 121.32 ? 92 GLU C N 1 ATOM 720 C CA . GLU A 1 92 ? -44.585 -23.709 -31.223 1.00 121.32 ? 92 GLU C CA 1 ATOM 721 C C . GLU A 1 92 ? -43.279 -22.946 -31.474 1.00 121.32 ? 92 GLU C C 1 ATOM 722 O O . GLU A 1 92 ? -43.246 -21.904 -32.118 1.00 121.32 ? 92 GLU C O 1 ATOM 723 C CB . GLU A 1 92 ? -44.794 -24.724 -32.333 1.00 132.78 ? 92 GLU C CB 1 ATOM 724 C CG . GLU A 1 92 ? -44.632 -24.019 -33.665 1.00 132.78 ? 92 GLU C CG 1 ATOM 725 C CD . GLU A 1 92 ? -45.861 -23.206 -34.031 1.00 132.78 ? 92 GLU C CD 1 ATOM 726 O OE1 . GLU A 1 92 ? -45.730 -22.257 -34.838 1.00 132.78 ? 92 GLU C OE1 1 ATOM 727 O OE2 . GLU A 1 92 ? -46.957 -23.524 -33.526 1.00 132.78 ? 92 GLU C OE2 1 ATOM 728 N N . VAL A 1 93 ? -42.208 -23.443 -30.883 1.00 66.09 ? 93 VAL C N 1 ATOM 729 C CA . VAL A 1 93 ? -40.901 -22.864 -31.020 1.00 66.09 ? 93 VAL C CA 1 ATOM 730 C C . VAL A 1 93 ? -39.881 -23.974 -31.148 1.00 66.09 ? 93 VAL C C 1 ATOM 731 O O . VAL A 1 93 ? -40.040 -25.012 -30.501 1.00 66.09 ? 93 VAL C O 1 ATOM 732 C CB . VAL A 1 93 ? -40.593 -21.960 -29.841 1.00 78.33 ? 93 VAL C CB 1 ATOM 733 C CG1 . VAL A 1 93 ? -40.633 -22.739 -28.529 1.00 78.33 ? 93 VAL C CG1 1 ATOM 734 C CG2 . VAL A 1 93 ? -39.294 -21.289 -30.080 1.00 78.33 ? 93 VAL C CG2 1 ATOM 735 N N . GLN A 1 94 ? -38.886 -23.821 -32.011 1.00 77.56 ? 94 GLN C N 1 ATOM 736 C CA . GLN A 1 94 ? -37.844 -24.842 -32.131 1.00 77.56 ? 94 GLN C CA 1 ATOM 737 C C . GLN A 1 94 ? -36.608 -24.384 -31.345 1.00 77.56 ? 94 GLN C C 1 ATOM 738 O O . GLN A 1 94 ? -36.098 -23.284 -31.548 1.00 77.56 ? 94 GLN C O 1 ATOM 739 C CB . GLN A 1 94 ? -37.498 -25.060 -33.620 1.00 97.43 ? 94 GLN C CB 1 ATOM 740 C CG . GLN A 1 94 ? -36.409 -26.111 -33.942 1.00 97.43 ? 94 GLN C CG 1 ATOM 741 C CD . GLN A 1 94 ? -36.728 -27.531 -33.469 1.00 97.43 ? 94 GLN C CD 1 ATOM 742 O OE1 . GLN A 1 94 ? -37.802 -28.058 -33.731 1.00 97.43 ? 94 GLN C OE1 1 ATOM 743 N NE2 . GLN A 1 94 ? -35.776 -28.157 -32.772 1.00 97.43 ? 94 GLN C NE2 1 ATOM 744 N N . LEU A 1 95 ? -36.110 -25.227 -30.445 1.00 78.21 ? 95 LEU C N 1 ATOM 745 C CA . LEU A 1 95 ? -34.932 -24.847 -29.670 1.00 78.21 ? 95 LEU C CA 1 ATOM 746 C C . LEU A 1 95 ? -33.769 -25.822 -29.898 1.00 78.21 ? 95 LEU C C 1 ATOM 747 O O . LEU A 1 95 ? -33.897 -27.050 -29.622 1.00 78.21 ? 95 LEU C O 1 ATOM 748 C CB . LEU A 1 95 ? -35.299 -24.876 -28.193 1.00 71.16 ? 95 LEU C CB 1 ATOM 749 C CG . LEU A 1 95 ? -34.238 -24.518 -27.210 1.00 71.16 ? 95 LEU C CG 1 ATOM 750 C CD1 . LEU A 1 95 ? -33.891 -23.108 -27.594 1.00 71.16 ? 95 LEU C CD1 1 ATOM 751 C CD2 . LEU A 1 95 ? -34.705 -24.648 -25.770 1.00 71.16 ? 95 LEU C CD2 1 ATOM 752 N N . LEU A 1 96 ? -32.621 -25.263 -30.307 1.00 74.37 ? 96 LEU C N 1 ATOM 753 C CA . LEU A 1 96 ? -31.396 -26.051 -30.531 1.00 74.37 ? 96 LEU C CA 1 ATOM 754 C C . LEU A 1 96 ? -30.277 -25.604 -29.591 1.00 74.37 ? 96 LEU C C 1 ATOM 755 O O . LEU A 1 96 ? -30.153 -24.405 -29.305 1.00 74.37 ? 96 LEU C O 1 ATOM 756 C CB . LEU A 1 96 ? -30.927 -26.001 -31.990 1.00 90.81 ? 96 LEU C CB 1 ATOM 757 C CG . LEU A 1 96 ? -31.921 -26.533 -33.010 1.00 90.81 ? 96 LEU C CG 1 ATOM 758 C CD1 . LEU A 1 96 ? -31.339 -26.430 -34.429 1.00 90.81 ? 96 LEU C CD1 1 ATOM 759 C CD2 . LEU A 1 96 ? -32.234 -27.992 -32.666 1.00 90.81 ? 96 LEU C CD2 1 ATOM 760 N N . VAL A 1 97 ? -29.477 -26.563 -29.107 1.00 123.79 ? 97 VAL C N 1 ATOM 761 C CA . VAL A 1 97 ? -28.373 -26.276 -28.193 1.00 123.79 ? 97 VAL C CA 1 ATOM 762 C C . VAL A 1 97 ? -27.052 -26.721 -28.812 1.00 123.79 ? 97 VAL C C 1 ATOM 763 O O . VAL A 1 97 ? -26.917 -27.822 -29.311 1.00 123.79 ? 97 VAL C O 1 ATOM 764 C CB . VAL A 1 97 ? -28.563 -27.077 -26.937 1.00 72.98 ? 97 VAL C CB 1 ATOM 765 C CG1 . VAL A 1 97 ? -27.458 -26.821 -25.979 1.00 72.98 ? 97 VAL C CG1 1 ATOM 766 C CG2 . VAL A 1 97 ? -29.839 -26.705 -26.332 1.00 72.98 ? 97 VAL C CG2 1 ATOM 767 N N . PHE A 1 98 ? -26.105 -25.799 -28.828 1.00 131.22 ? 98 PHE C N 1 ATOM 768 C CA . PHE A 1 98 ? -24.800 -26.030 -29.395 1.00 131.22 ? 98 PHE C CA 1 ATOM 769 C C . PHE A 1 98 ? -23.677 -25.864 -28.391 1.00 131.22 ? 98 PHE C C 1 ATOM 770 O O . PHE A 1 98 ? -23.781 -24.954 -27.588 1.00 131.22 ? 98 PHE C O 1 ATOM 771 C CB . PHE A 1 98 ? -24.637 -25.073 -30.538 1.00 93.61 ? 98 PHE C CB 1 ATOM 772 C CG . PHE A 1 98 ? -25.499 -25.425 -31.633 1.00 93.61 ? 98 PHE C CG 1 ATOM 773 C CD1 . PHE A 1 98 ? -25.114 -26.264 -32.623 1.00 93.61 ? 98 PHE C CD1 1 ATOM 774 C CD2 . PHE A 1 98 ? -26.774 -24.954 -31.614 1.00 93.61 ? 98 PHE C CD2 1 ATOM 775 C CE1 . PHE A 1 98 ? -26.018 -26.652 -33.583 1.00 93.61 ? 98 PHE C CE1 1 ATOM 776 C CE2 . PHE A 1 98 ? -27.702 -25.316 -32.562 1.00 93.61 ? 98 PHE C CE2 1 ATOM 777 C CZ . PHE A 1 98 ? -27.334 -26.170 -33.545 1.00 93.61 ? 98 PHE C CZ 1 ATOM 778 N N . GLY A 1 99 ? -22.619 -26.668 -28.350 1.00 105.81 ? 99 GLY C N 1 ATOM 779 C CA . GLY A 1 99 ? -21.618 -26.239 -27.378 1.00 105.81 ? 99 GLY C CA 1 ATOM 780 C C . GLY A 1 99 ? -20.188 -26.125 -27.858 1.00 105.81 ? 99 GLY C C 1 ATOM 781 O O . GLY A 1 99 ? -19.723 -26.984 -28.582 1.00 105.81 ? 99 GLY C O 1 ATOM 782 N N . LEU A 1 100 ? -19.464 -25.093 -27.435 1.00 77.44 ? 100 LEU C N 1 ATOM 783 C CA . LEU A 1 100 ? -18.076 -25.046 -27.846 1.00 77.44 ? 100 LEU C CA 1 ATOM 784 C C . LEU A 1 100 ? -17.110 -25.334 -26.779 1.00 77.44 ? 100 LEU C C 1 ATOM 785 O O . LEU A 1 100 ? -17.266 -24.947 -25.684 1.00 77.44 ? 100 LEU C O 1 ATOM 786 C CB . LEU A 1 100 ? -17.596 -23.740 -28.494 1.00 61.40 ? 100 LEU C CB 1 ATOM 787 C CG . LEU A 1 100 ? -18.095 -23.064 -29.748 1.00 61.40 ? 100 LEU C CG 1 ATOM 788 C CD1 . LEU A 1 100 ? -17.262 -21.807 -29.912 1.00 61.40 ? 100 LEU C CD1 1 ATOM 789 C CD2 . LEU A 1 100 ? -17.870 -23.967 -31.012 1.00 61.40 ? 100 LEU C CD2 1 ATOM 790 N N . THR A 1 101 ? -16.106 -26.082 -27.118 1.00 94.14 ? 101 THR C N 1 ATOM 791 C CA . THR A 1 101 ? -15.090 -26.363 -26.175 1.00 94.14 ? 101 THR C CA 1 ATOM 792 C C . THR A 1 101 ? -13.664 -26.352 -26.749 1.00 94.14 ? 101 THR C C 1 ATOM 793 O O . THR A 1 101 ? -13.408 -26.704 -27.903 1.00 94.14 ? 101 THR C O 1 ATOM 794 C CB . THR A 1 101 ? -15.458 -27.711 -25.479 1.00 111.87 ? 101 THR C CB 1 ATOM 795 O OG1 . THR A 1 101 ? -15.763 -28.701 -26.472 1.00 111.87 ? 101 THR C OG1 1 ATOM 796 C CG2 . THR A 1 101 ? -16.624 -27.558 -24.558 1.00 111.87 ? 101 THR C CG2 1 ATOM 797 N N . ALA A 1 102 ? -12.732 -25.995 -25.895 1.00 96.89 ? 102 ALA C N 1 ATOM 798 C CA . ALA A 1 102 ? -11.305 -25.976 -26.167 1.00 96.89 ? 102 ALA C CA 1 ATOM 799 C C . ALA A 1 102 ? -10.786 -27.385 -26.041 1.00 96.89 ? 102 ALA C C 1 ATOM 800 O O . ALA A 1 102 ? -11.455 -28.248 -25.493 1.00 96.89 ? 102 ALA C O 1 ATOM 801 C CB . ALA A 1 102 ? -10.590 -25.084 -25.218 1.00 93.62 ? 102 ALA C CB 1 ATOM 802 N N . ASN A 1 103 ? -9.633 -27.651 -26.611 1.00 116.51 ? 103 ASN C N 1 ATOM 803 C CA . ASN A 1 103 ? -9.058 -28.984 -26.516 1.00 116.51 ? 103 ASN C CA 1 ATOM 804 C C . ASN A 1 103 ? -8.787 -29.431 -25.046 1.00 116.51 ? 103 ASN C C 1 ATOM 805 O O . ASN A 1 103 ? -8.998 -30.606 -24.702 1.00 116.51 ? 103 ASN C O 1 ATOM 806 C CB . ASN A 1 103 ? -7.780 -29.080 -27.379 1.00 106.30 ? 103 ASN C CB 1 ATOM 807 C CG . ASN A 1 103 ? -6.707 -28.081 -26.971 1.00 106.30 ? 103 ASN C CG 1 ATOM 808 O OD1 . ASN A 1 103 ? -5.712 -27.915 -27.676 1.00 106.30 ? 103 ASN C OD1 1 ATOM 809 N ND2 . ASN A 1 103 ? -6.924 -27.380 -25.853 1.00 106.30 ? 103 ASN C ND2 1 ATOM 810 N N . SER A 1 104 ? -8.307 -28.530 -24.193 1.00 119.56 ? 104 SER C N 1 ATOM 811 C CA . SER A 1 104 ? -8.022 -28.870 -22.784 1.00 119.56 ? 104 SER C CA 1 ATOM 812 C C . SER A 1 104 ? -8.273 -27.629 -21.869 1.00 119.56 ? 104 SER C C 1 ATOM 813 O O . SER A 1 104 ? -8.515 -26.519 -22.397 1.00 119.56 ? 104 SER C O 1 ATOM 814 C CB . SER A 1 104 ? -6.591 -29.468 -22.628 1.00 114.23 ? 104 SER C CB 1 ATOM 815 O OG . SER A 1 104 ? -5.543 -28.568 -22.988 1.00 114.23 ? 104 SER C OG 1 ATOM 816 N N . ASP A 1 105 ? -8.270 -27.805 -20.530 1.00 131.48 ? 105 ASP C N 1 ATOM 817 C CA . ASP A 1 105 ? -8.644 -26.685 -19.622 1.00 131.48 ? 105 ASP C CA 1 ATOM 818 C C . ASP A 1 105 ? -7.929 -25.343 -19.538 1.00 131.48 ? 105 ASP C C 1 ATOM 819 O O . ASP A 1 105 ? -8.593 -24.308 -19.453 1.00 131.48 ? 105 ASP C O 1 ATOM 820 C CB . ASP A 1 105 ? -8.536 -27.115 -18.128 1.00 99.42 ? 105 ASP C CB 1 ATOM 821 C CG . ASP A 1 105 ? -9.584 -28.119 -17.658 1.00 99.42 ? 105 ASP C CG 1 ATOM 822 O OD1 . ASP A 1 105 ? -10.657 -28.277 -18.281 1.00 99.42 ? 105 ASP C OD1 1 ATOM 823 O OD2 . ASP A 1 105 ? -9.319 -28.771 -16.625 1.00 99.42 ? 105 ASP C OD2 1 ATOM 824 N N . THR A 1 106 ? -6.607 -25.321 -19.607 1.00 149.74 ? 106 THR C N 1 ATOM 825 C CA . THR A 1 106 ? -5.946 -24.039 -19.396 1.00 149.74 ? 106 THR C CA 1 ATOM 826 C C . THR A 1 106 ? -4.476 -23.829 -19.805 1.00 149.74 ? 106 THR C C 1 ATOM 827 O O . THR A 1 106 ? -3.787 -24.755 -20.279 1.00 149.74 ? 106 THR C O 1 ATOM 828 C CB . THR A 1 106 ? -6.180 -23.551 -17.914 1.00 182.96 ? 106 THR C CB 1 ATOM 829 O OG1 . THR A 1 106 ? -6.123 -22.118 -17.865 1.00 182.96 ? 106 THR C OG1 1 ATOM 830 C CG2 . THR A 1 106 ? -5.124 -24.119 -16.966 1.00 182.96 ? 106 THR C CG2 1 ATOM 831 N N . HIS A 1 107 ? -4.043 -22.571 -19.697 1.00 151.96 ? 107 HIS C N 1 ATOM 832 C CA . HIS A 1 107 ? -2.623 -22.242 -19.821 1.00 151.96 ? 107 HIS C CA 1 ATOM 833 C C . HIS A 1 107 ? -1.884 -22.746 -21.039 1.00 151.96 ? 107 HIS C C 1 ATOM 834 O O . HIS A 1 107 ? -0.795 -23.301 -20.897 1.00 151.96 ? 107 HIS C O 1 ATOM 835 C CB . HIS A 1 107 ? -1.893 -22.734 -18.521 1.00 150.48 ? 107 HIS C CB 1 ATOM 836 C CG . HIS A 1 107 ? -2.225 -21.945 -17.269 1.00 150.48 ? 107 HIS C CG 1 ATOM 837 N ND1 . HIS A 1 107 ? -2.214 -22.505 -16.003 1.00 150.48 ? 107 HIS C ND1 1 ATOM 838 C CD2 . HIS A 1 107 ? -2.540 -20.636 -17.088 1.00 150.48 ? 107 HIS C CD2 1 ATOM 839 C CE1 . HIS A 1 107 ? -2.517 -21.584 -15.103 1.00 150.48 ? 107 HIS C CE1 1 ATOM 840 N NE2 . HIS A 1 107 ? -2.719 -20.441 -15.736 1.00 150.48 ? 107 HIS C NE2 1 ATOM 841 N N . LEU A 1 108 ? -2.469 -22.622 -22.224 1.00 82.95 ? 108 LEU C N 1 ATOM 842 C CA . LEU A 1 108 ? -1.731 -23.087 -23.425 1.00 82.95 ? 108 LEU C CA 1 ATOM 843 C C . LEU A 1 108 ? -0.780 -22.034 -24.024 1.00 82.95 ? 108 LEU C C 1 ATOM 844 O O . LEU A 1 108 ? -1.145 -20.915 -24.350 1.00 82.95 ? 108 LEU C O 1 ATOM 845 C CB . LEU A 1 108 ? -2.702 -23.625 -24.487 1.00 110.72 ? 108 LEU C CB 1 ATOM 846 C CG . LEU A 1 108 ? -3.496 -24.806 -23.906 1.00 110.72 ? 108 LEU C CG 1 ATOM 847 C CD1 . LEU A 1 108 ? -4.449 -25.307 -24.966 1.00 110.72 ? 108 LEU C CD1 1 ATOM 848 C CD2 . LEU A 1 108 ? -2.531 -25.931 -23.384 1.00 110.72 ? 108 LEU C CD2 1 ATOM 849 N N . LEU A 1 109 ? 0.423 -22.534 -24.258 1.00 73.35 ? 109 LEU C N 1 ATOM 850 C CA . LEU A 1 109 ? 1.681 -21.896 -24.676 1.00 73.35 ? 109 LEU C CA 1 ATOM 851 C C . LEU A 1 109 ? 2.050 -22.282 -26.107 1.00 73.35 ? 109 LEU C C 1 ATOM 852 O O . LEU A 1 109 ? 1.482 -23.206 -26.649 1.00 73.35 ? 109 LEU C O 1 ATOM 853 C CB . LEU A 1 109 ? 2.747 -22.278 -23.622 1.00 86.00 ? 109 LEU C CB 1 ATOM 854 C CG . LEU A 1 109 ? 2.544 -21.606 -22.225 1.00 86.00 ? 109 LEU C CG 1 ATOM 855 C CD1 . LEU A 1 109 ? 3.442 -22.182 -21.192 1.00 86.00 ? 109 LEU C CD1 1 ATOM 856 C CD2 . LEU A 1 109 ? 2.949 -20.110 -22.334 1.00 86.00 ? 109 LEU C CD2 1 ATOM 857 N N . GLN A 1 110 ? 2.973 -21.557 -26.724 1.00 101.42 ? 110 GLN C N 1 ATOM 858 C CA . GLN A 1 110 ? 3.327 -21.686 -28.145 1.00 101.42 ? 110 GLN C CA 1 ATOM 859 C C . GLN A 1 110 ? 3.861 -22.905 -28.872 1.00 101.42 ? 110 GLN C C 1 ATOM 860 O O . GLN A 1 110 ? 4.650 -23.687 -28.333 1.00 101.42 ? 110 GLN C O 1 ATOM 861 C CB . GLN A 1 110 ? 4.303 -20.599 -28.491 1.00 84.44 ? 110 GLN C CB 1 ATOM 862 C CG . GLN A 1 110 ? 3.759 -19.245 -28.513 1.00 84.44 ? 110 GLN C CG 1 ATOM 863 C CD . GLN A 1 110 ? 4.837 -18.278 -28.869 1.00 84.44 ? 110 GLN C CD 1 ATOM 864 O OE1 . GLN A 1 110 ? 4.560 -17.147 -29.243 1.00 84.44 ? 110 GLN C OE1 1 ATOM 865 N NE2 . GLN A 1 110 ? 6.092 -18.714 -28.746 1.00 84.44 ? 110 GLN C NE2 1 ATOM 866 N N . GLY A 1 111 ? 3.332 -23.046 -30.098 1.00 94.35 ? 111 GLY C N 1 ATOM 867 C CA . GLY A 1 111 ? 3.663 -24.102 -31.055 1.00 94.35 ? 111 GLY C CA 1 ATOM 868 C C . GLY A 1 111 ? 2.724 -25.237 -30.801 1.00 94.35 ? 111 GLY C C 1 ATOM 869 O O . GLY A 1 111 ? 2.563 -26.192 -31.574 1.00 94.35 ? 111 GLY C O 1 ATOM 870 N N . GLN A 1 112 ? 2.046 -25.044 -29.686 1.00 108.78 ? 112 GLN C N 1 ATOM 871 C CA . GLN A 1 112 ? 1.056 -25.952 -29.158 1.00 108.78 ? 112 GLN C CA 1 ATOM 872 C C . GLN A 1 112 ? -0.147 -25.564 -30.041 1.00 108.78 ? 112 GLN C C 1 ATOM 873 O O . GLN A 1 112 ? -0.169 -24.480 -30.611 1.00 108.78 ? 112 GLN C O 1 ATOM 874 C CB . GLN A 1 112 ? 0.877 -25.640 -27.653 1.00 72.40 ? 112 GLN C CB 1 ATOM 875 C CG . GLN A 1 112 ? 2.161 -26.059 -26.770 1.00 72.40 ? 112 GLN C CG 1 ATOM 876 C CD . GLN A 1 112 ? 2.025 -25.752 -25.258 1.00 72.40 ? 112 GLN C CD 1 ATOM 877 O OE1 . GLN A 1 112 ? 3.025 -25.491 -24.598 1.00 72.40 ? 112 GLN C OE1 1 ATOM 878 N NE2 . GLN A 1 112 ? 0.779 -25.832 -24.704 1.00 72.40 ? 112 GLN C NE2 1 ATOM 879 N N . SER A 1 113 ? -1.149 -26.411 -30.165 1.00 96.09 ? 113 SER C N 1 ATOM 880 C CA . SER A 1 113 ? -2.223 -26.066 -31.062 1.00 96.09 ? 113 SER C CA 1 ATOM 881 C C . SER A 1 113 ? -3.583 -26.101 -30.410 1.00 96.09 ? 113 SER C C 1 ATOM 882 O O . SER A 1 113 ? -3.831 -26.849 -29.481 1.00 96.09 ? 113 SER C O 1 ATOM 883 C CB . SER A 1 113 ? -2.222 -27.042 -32.244 1.00 94.95 ? 113 SER C CB 1 ATOM 884 O OG . SER A 1 113 ? -2.409 -28.391 -31.822 1.00 94.95 ? 113 SER C OG 1 ATOM 885 N N . LEU A 1 114 ? -4.457 -25.250 -30.924 1.00 133.73 ? 114 LEU C N 1 ATOM 886 C CA . LEU A 1 114 ? -5.837 -25.097 -30.469 1.00 133.73 ? 114 LEU C CA 1 ATOM 887 C C . LEU A 1 114 ? -6.938 -25.746 -31.297 1.00 133.73 ? 114 LEU C C 1 ATOM 888 O O . LEU A 1 114 ? -7.025 -25.514 -32.491 1.00 133.73 ? 114 LEU C O 1 ATOM 889 C CB . LEU A 1 114 ? -6.178 -23.610 -30.410 1.00 122.05 ? 114 LEU C CB 1 ATOM 890 C CG . LEU A 1 114 ? -7.586 -23.196 -29.954 1.00 122.05 ? 114 LEU C CG 1 ATOM 891 C CD1 . LEU A 1 114 ? -7.899 -23.673 -28.546 1.00 122.05 ? 114 LEU C CD1 1 ATOM 892 C CD2 . LEU A 1 114 ? -7.720 -21.687 -30.068 1.00 122.05 ? 114 LEU C CD2 1 ATOM 893 N N . THR A 1 115 ? -7.746 -26.593 -30.684 1.00 103.49 ? 115 THR C N 1 ATOM 894 C CA . THR A 1 115 ? -8.901 -27.136 -31.374 1.00 103.49 ? 115 THR C CA 1 ATOM 895 C C . THR A 1 115 ? -10.210 -26.764 -30.639 1.00 103.49 ? 115 THR C C 1 ATOM 896 O O . THR A 1 115 ? -10.382 -27.002 -29.450 1.00 103.49 ? 115 THR C O 1 ATOM 897 C CB . THR A 1 115 ? -8.762 -28.670 -31.570 1.00 138.54 ? 115 THR C CB 1 ATOM 898 O OG1 . THR A 1 115 ? -7.593 -28.955 -32.346 1.00 138.54 ? 115 THR C OG1 1 ATOM 899 C CG2 . THR A 1 115 ? -9.973 -29.245 -32.232 1.00 138.54 ? 115 THR C CG2 1 ATOM 900 N N . LEU A 1 116 ? -11.166 -26.241 -31.379 1.00 105.73 ? 116 LEU C N 1 ATOM 901 C CA . LEU A 1 116 ? -12.453 -25.858 -30.835 1.00 105.73 ? 116 LEU C CA 1 ATOM 902 C C . LEU A 1 116 ? -13.317 -26.905 -31.466 1.00 105.73 ? 116 LEU C C 1 ATOM 903 O O . LEU A 1 116 ? -13.170 -27.213 -32.632 1.00 105.73 ? 116 LEU C O 1 ATOM 904 C CB . LEU A 1 116 ? -12.834 -24.468 -31.346 1.00 79.89 ? 116 LEU C CB 1 ATOM 905 C CG . LEU A 1 116 ? -11.849 -23.348 -30.960 1.00 79.89 ? 116 LEU C CG 1 ATOM 906 C CD1 . LEU A 1 116 ? -12.147 -22.012 -31.685 1.00 79.89 ? 116 LEU C CD1 1 ATOM 907 C CD2 . LEU A 1 116 ? -11.943 -23.142 -29.465 1.00 79.89 ? 116 LEU C CD2 1 ATOM 908 N N . THR A 1 117 ? -14.260 -27.436 -30.730 1.00 128.34 ? 117 THR C N 1 ATOM 909 C CA . THR A 1 117 ? -15.083 -28.438 -31.350 1.00 128.34 ? 117 THR C CA 1 ATOM 910 C C . THR A 1 117 ? -16.478 -27.941 -31.059 1.00 128.34 ? 117 THR C C 1 ATOM 911 O O . THR A 1 117 ? -16.732 -27.273 -30.058 1.00 128.34 ? 117 THR C O 1 ATOM 912 C CB . THR A 1 117 ? -14.915 -29.814 -30.722 1.00 88.49 ? 117 THR C CB 1 ATOM 913 O OG1 . THR A 1 117 ? -15.278 -29.739 -29.343 1.00 88.49 ? 117 THR C OG1 1 ATOM 914 C CG2 . THR A 1 117 ? -13.480 -30.276 -30.858 1.00 88.49 ? 117 THR C CG2 1 ATOM 915 N N . LEU A 1 118 ? -17.382 -28.262 -31.966 1.00 103.50 ? 118 LEU C N 1 ATOM 916 C CA . LEU A 1 118 ? -18.724 -27.817 -31.842 1.00 103.50 ? 118 LEU C CA 1 ATOM 917 C C . LEU A 1 118 ? -19.581 -29.061 -31.730 1.00 103.50 ? 118 LEU C C 1 ATOM 918 O O . LEU A 1 118 ? -19.575 -29.920 -32.598 1.00 103.50 ? 118 LEU C O 1 ATOM 919 C CB . LEU A 1 118 ? -19.056 -27.051 -33.096 1.00 83.52 ? 118 LEU C CB 1 ATOM 920 C CG . LEU A 1 118 ? -20.447 -26.513 -33.117 1.00 83.52 ? 118 LEU C CG 1 ATOM 921 C CD1 . LEU A 1 118 ? -20.511 -25.436 -32.115 1.00 83.52 ? 118 LEU C CD1 1 ATOM 922 C CD2 . LEU A 1 118 ? -20.825 -26.017 -34.443 1.00 83.52 ? 118 LEU C CD2 1 ATOM 923 N N . GLU A 1 119 ? -20.407 -29.111 -30.699 1.00 118.17 ? 119 GLU C N 1 ATOM 924 C CA . GLU A 1 119 ? -21.250 -30.277 -30.540 1.00 118.17 ? 119 GLU C CA 1 ATOM 925 C C . GLU A 1 119 ? -22.554 -29.638 -30.912 1.00 118.17 ? 119 GLU C C 1 ATOM 926 O O . GLU A 1 119 ? -22.961 -28.627 -30.344 1.00 118.17 ? 119 GLU C O 1 ATOM 927 C CB . GLU A 1 119 ? -21.285 -30.746 -29.079 1.00 107.89 ? 119 GLU C CB 1 ATOM 928 C CG . GLU A 1 119 ? -21.827 -29.701 -28.124 1.00 107.89 ? 119 GLU C CG 1 ATOM 929 C CD . GLU A 1 119 ? -21.652 -30.081 -26.679 1.00 107.89 ? 119 GLU C CD 1 ATOM 930 O OE1 . GLU A 1 119 ? -22.023 -31.216 -26.306 1.00 107.89 ? 119 GLU C OE1 1 ATOM 931 O OE2 . GLU A 1 119 ? -21.153 -29.232 -25.915 1.00 107.89 ? 119 GLU C OE2 1 ATOM 932 N N . SER A 1 120 ? -23.241 -30.307 -31.815 1.00 102.68 ? 120 SER C N 1 ATOM 933 C CA . SER A 1 120 ? -24.476 -29.823 -32.361 1.00 102.68 ? 120 SER C CA 1 ATOM 934 C C . SER A 1 120 ? -25.441 -30.908 -31.975 1.00 102.68 ? 120 SER C C 1 ATOM 935 O O . SER A 1 120 ? -25.043 -32.062 -31.793 1.00 102.68 ? 120 SER C O 1 ATOM 936 C CB . SER A 1 120 ? -24.331 -29.687 -33.888 1.00 168.81 ? 120 SER C CB 1 ATOM 937 O OG . SER A 1 120 ? -25.531 -29.257 -34.501 1.00 168.81 ? 120 SER C OG 1 ATOM 938 N N . PRO A 1 121 ? -26.711 -30.548 -31.764 1.00 134.77 ? 121 PRO C N 1 ATOM 939 C CA . PRO A 1 121 ? -27.700 -31.536 -31.388 1.00 134.77 ? 121 PRO C CA 1 ATOM 940 C C . PRO A 1 121 ? -28.057 -32.499 -32.485 1.00 134.77 ? 121 PRO C C 1 ATOM 941 O O . PRO A 1 121 ? -27.904 -32.195 -33.656 1.00 134.77 ? 121 PRO C O 1 ATOM 942 C CB . PRO A 1 121 ? -28.821 -30.641 -30.952 1.00 144.31 ? 121 PRO C CB 1 ATOM 943 C CG . PRO A 1 121 ? -28.960 -29.879 -32.199 1.00 144.31 ? 121 PRO C CG 1 ATOM 944 C CD . PRO A 1 121 ? -27.445 -29.372 -32.277 1.00 144.31 ? 121 PRO C CD 1 ATOM 945 N N . PRO A 1 122 ? -28.551 -33.677 -32.118 1.00 125.99 ? 122 PRO C N 1 ATOM 946 C CA . PRO A 1 122 ? -28.910 -34.653 -33.153 1.00 125.99 ? 122 PRO C CA 1 ATOM 947 C C . PRO A 1 122 ? -29.561 -34.011 -34.394 1.00 125.99 ? 122 PRO C C 1 ATOM 948 O O . PRO A 1 122 ? -30.504 -33.220 -34.265 1.00 125.99 ? 122 PRO C O 1 ATOM 949 C CB . PRO A 1 122 ? -29.844 -35.611 -32.412 1.00 89.46 ? 122 PRO C CB 1 ATOM 950 C CG . PRO A 1 122 ? -30.207 -34.848 -31.064 1.00 89.46 ? 122 PRO C CG 1 ATOM 951 C CD . PRO A 1 122 ? -28.983 -34.097 -30.771 1.00 89.46 ? 122 PRO C CD 1 ATOM 952 N N . GLY A 1 123 ? -29.061 -34.336 -35.589 1.00 103.41 ? 123 GLY C N 1 ATOM 953 C CA . GLY A 1 123 ? -29.635 -33.771 -36.812 1.00 103.41 ? 123 GLY C CA 1 ATOM 954 C C . GLY A 1 123 ? -29.525 -32.305 -37.265 1.00 103.41 ? 123 GLY C C 1 ATOM 955 O O . GLY A 1 123 ? -30.478 -31.819 -37.898 1.00 103.41 ? 123 GLY C O 1 ATOM 956 N N . SER A 1 124 ? -28.448 -31.578 -36.925 1.00 92.85 ? 124 SER C N 1 ATOM 957 C CA . SER A 1 124 ? -28.320 -30.168 -37.340 1.00 92.85 ? 124 SER C CA 1 ATOM 958 C C . SER A 1 124 ? -27.061 -29.658 -38.004 1.00 92.85 ? 124 SER C C 1 ATOM 959 O O . SER A 1 124 ? -25.965 -30.186 -37.795 1.00 92.85 ? 124 SER C O 1 ATOM 960 C CB . SER A 1 124 ? -28.670 -29.236 -36.182 1.00 123.35 ? 124 SER C CB 1 ATOM 961 O OG . SER A 1 124 ? -30.013 -29.447 -35.750 1.00 123.35 ? 124 SER C OG 1 ATOM 962 N N . SER A 1 125 ? -27.239 -28.660 -38.869 1.00 133.67 ? 125 SER C N 1 ATOM 963 C CA . SER A 1 125 ? -26.117 -28.021 -39.579 1.00 133.67 ? 125 SER C CA 1 ATOM 964 C C . SER A 1 125 ? -25.178 -27.154 -38.705 1.00 133.67 ? 125 SER C C 1 ATOM 965 O O . SER A 1 125 ? -25.624 -26.296 -37.951 1.00 133.67 ? 125 SER C O 1 ATOM 966 C CB . SER A 1 125 ? -26.652 -27.149 -40.748 1.00 108.09 ? 125 SER C CB 1 ATOM 967 O OG . SER A 1 125 ? -27.196 -27.912 -41.831 1.00 108.09 ? 125 SER C OG 1 ATOM 968 N N . PRO A 1 126 ? -23.867 -27.369 -38.803 1.00 107.43 ? 126 PRO C N 1 ATOM 969 C CA . PRO A 1 126 ? -23.053 -26.499 -37.961 1.00 107.43 ? 126 PRO C CA 1 ATOM 970 C C . PRO A 1 126 ? -21.866 -25.831 -38.701 1.00 107.43 ? 126 PRO C C 1 ATOM 971 O O . PRO A 1 126 ? -20.958 -26.503 -39.175 1.00 107.43 ? 126 PRO C O 1 ATOM 972 C CB . PRO A 1 126 ? -22.596 -27.447 -36.827 1.00 101.40 ? 126 PRO C CB 1 ATOM 973 C CG . PRO A 1 126 ? -23.196 -28.859 -37.183 1.00 101.40 ? 126 PRO C CG 1 ATOM 974 C CD . PRO A 1 126 ? -23.380 -28.752 -38.668 1.00 101.40 ? 126 PRO C CD 1 ATOM 975 N N . SER A 1 127 ? -21.872 -24.503 -38.764 1.00 139.07 ? 127 SER C N 1 ATOM 976 C CA . SER A 1 127 ? -20.789 -23.755 -39.409 1.00 139.07 ? 127 SER C CA 1 ATOM 977 C C . SER A 1 127 ? -20.263 -22.754 -38.381 1.00 139.07 ? 127 SER C C 1 ATOM 978 O O . SER A 1 127 ? -21.051 -22.159 -37.649 1.00 139.07 ? 127 SER C O 1 ATOM 979 C CB . SER A 1 127 ? -21.338 -22.988 -40.600 1.00 120.59 ? 127 SER C CB 1 ATOM 980 O OG . SER A 1 127 ? -22.342 -22.073 -40.193 1.00 120.59 ? 127 SER C OG 1 ATOM 981 N N . VAL A 1 128 ? -18.944 -22.567 -38.328 1.00 113.41 ? 128 VAL C N 1 ATOM 982 C CA . VAL A 1 128 ? -18.312 -21.662 -37.363 1.00 113.41 ? 128 VAL C CA 1 ATOM 983 C C . VAL A 1 128 ? -17.480 -20.494 -37.804 1.00 113.41 ? 128 VAL C C 1 ATOM 984 O O . VAL A 1 128 ? -16.551 -20.694 -38.566 1.00 113.41 ? 128 VAL C O 1 ATOM 985 C CB . VAL A 1 128 ? -17.403 -22.441 -36.423 1.00 75.45 ? 128 VAL C CB 1 ATOM 986 C CG1 . VAL A 1 128 ? -16.779 -21.501 -35.460 1.00 75.45 ? 128 VAL C CG1 1 ATOM 987 C CG2 . VAL A 1 128 ? -18.215 -23.472 -35.607 1.00 75.45 ? 128 VAL C CG2 1 ATOM 988 N N . GLN A 1 129 ? -17.735 -19.294 -37.288 1.00 118.64 ? 129 GLN C N 1 ATOM 989 C CA . GLN A 1 129 ? -16.843 -18.182 -37.635 1.00 118.64 ? 129 GLN C CA 1 ATOM 990 C C . GLN A 1 129 ? -16.205 -17.714 -36.342 1.00 118.64 ? 129 GLN C C 1 ATOM 991 O O . GLN A 1 129 ? -16.936 -17.495 -35.368 1.00 118.64 ? 129 GLN C O 1 ATOM 992 C CB . GLN A 1 129 ? -17.502 -16.919 -38.166 1.00 118.15 ? 129 GLN C CB 1 ATOM 993 C CG . GLN A 1 129 ? -16.362 -15.937 -38.443 1.00 118.15 ? 129 GLN C CG 1 ATOM 994 C CD . GLN A 1 129 ? -16.775 -14.611 -38.975 1.00 118.15 ? 129 GLN C CD 1 ATOM 995 O OE1 . GLN A 1 129 ? -17.566 -13.920 -38.357 1.00 118.15 ? 129 GLN C OE1 1 ATOM 996 N NE2 . GLN A 1 129 ? -16.254 -14.238 -40.129 1.00 118.15 ? 129 GLN C NE2 1 ATOM 997 N N . CYS A 1 130 ? -14.874 -17.571 -36.301 1.00 94.58 ? 130 CYS C N 1 ATOM 998 C CA . CYS A 1 130 ? -14.295 -17.060 -35.088 1.00 94.58 ? 130 CYS C CA 1 ATOM 999 C C . CYS A 1 130 ? -13.409 -15.832 -35.384 1.00 94.58 ? 130 CYS C C 1 ATOM 1000 O O . CYS A 1 130 ? -12.659 -15.889 -36.307 1.00 94.58 ? 130 CYS C O 1 ATOM 1001 C CB . CYS A 1 130 ? -13.582 -18.216 -34.383 1.00 136.06 ? 130 CYS C CB 1 ATOM 1002 S SG . CYS A 1 130 ? -13.899 -18.184 -32.575 1.00 136.06 ? 130 CYS C SG 1 ATOM 1003 N N . ARG A 1 131 ? -13.554 -14.694 -34.684 1.00 139.04 ? 131 ARG C N 1 ATOM 1004 C CA . ARG A 1 131 ? -12.660 -13.543 -34.936 1.00 139.04 ? 131 ARG C CA 1 ATOM 1005 C C . ARG A 1 131 ? -11.661 -13.602 -33.819 1.00 139.04 ? 131 ARG C C 1 ATOM 1006 O O . ARG A 1 131 ? -12.020 -13.569 -32.651 1.00 139.04 ? 131 ARG C O 1 ATOM 1007 C CB . ARG A 1 131 ? -13.363 -12.171 -34.900 1.00 125.59 ? 131 ARG C CB 1 ATOM 1008 C CG . ARG A 1 131 ? -14.304 -11.974 -36.092 1.00 125.59 ? 131 ARG C CG 1 ATOM 1009 C CD . ARG A 1 131 ? -15.062 -10.627 -36.155 1.00 125.59 ? 131 ARG C CD 1 ATOM 1010 N NE . ARG A 1 131 ? -15.974 -10.638 -37.312 1.00 125.59 ? 131 ARG C NE 1 ATOM 1011 C CZ . ARG A 1 131 ? -16.742 -9.624 -37.719 1.00 125.59 ? 131 ARG C CZ 1 ATOM 1012 N NH1 . ARG A 1 131 ? -16.722 -8.459 -37.083 1.00 125.59 ? 131 ARG C NH1 1 ATOM 1013 N NH2 . ARG A 1 131 ? -17.585 -9.801 -38.742 1.00 125.59 ? 131 ARG C NH2 1 ATOM 1014 N N . SER A 1 132 ? -10.387 -13.600 -34.176 1.00 144.46 ? 132 SER C N 1 ATOM 1015 C CA . SER A 1 132 ? -9.340 -13.732 -33.176 1.00 144.46 ? 132 SER C CA 1 ATOM 1016 C C . SER A 1 132 ? -9.278 -12.477 -32.345 1.00 144.46 ? 132 SER C C 1 ATOM 1017 O O . SER A 1 132 ? -9.826 -11.443 -32.713 1.00 144.46 ? 132 SER C O 1 ATOM 1018 C CB . SER A 1 132 ? -7.978 -14.015 -33.825 1.00 113.37 ? 132 SER C CB 1 ATOM 1019 O OG . SER A 1 132 ? -7.580 -12.977 -34.694 1.00 113.37 ? 132 SER C OG 1 ATOM 1020 N N . PRO A 1 133 ? -8.687 -12.571 -31.161 1.00 107.64 ? 133 PRO C N 1 ATOM 1021 C CA . PRO A 1 133 ? -8.615 -11.356 -30.337 1.00 107.64 ? 133 PRO C CA 1 ATOM 1022 C C . PRO A 1 133 ? -8.011 -10.351 -31.305 1.00 107.64 ? 133 PRO C C 1 ATOM 1023 O O . PRO A 1 133 ? -8.328 -9.167 -31.311 1.00 107.64 ? 133 PRO C O 1 ATOM 1024 C CB . PRO A 1 133 ? -7.652 -11.740 -29.230 1.00 79.90 ? 133 PRO C CB 1 ATOM 1025 C CG . PRO A 1 133 ? -7.675 -13.279 -29.252 1.00 79.90 ? 133 PRO C CG 1 ATOM 1026 C CD . PRO A 1 133 ? -7.773 -13.619 -30.696 1.00 79.90 ? 133 PRO C CD 1 ATOM 1027 N N . ARG A 1 134 ? -7.106 -10.905 -32.105 1.00 129.44 ? 134 ARG C N 1 ATOM 1028 C CA . ARG A 1 134 ? -6.346 -10.282 -33.182 1.00 129.44 ? 134 ARG C CA 1 ATOM 1029 C C . ARG A 1 134 ? -7.301 -9.732 -34.247 1.00 129.44 ? 134 ARG C C 1 ATOM 1030 O O . ARG A 1 134 ? -7.142 -8.616 -34.765 1.00 129.44 ? 134 ARG C O 1 ATOM 1031 C CB . ARG A 1 134 ? -5.516 -11.365 -33.868 1.00 103.61 ? 134 ARG C CB 1 ATOM 1032 C CG . ARG A 1 134 ? -4.343 -11.977 -33.120 1.00 103.61 ? 134 ARG C CG 1 ATOM 1033 C CD . ARG A 1 134 ? -3.737 -13.008 -34.069 1.00 103.61 ? 134 ARG C CD 1 ATOM 1034 N NE . ARG A 1 134 ? -4.688 -14.085 -34.457 1.00 103.61 ? 134 ARG C NE 1 ATOM 1035 C CZ . ARG A 1 134 ? -4.623 -14.809 -35.584 1.00 103.61 ? 134 ARG C CZ 1 ATOM 1036 N NH1 . ARG A 1 134 ? -3.672 -14.569 -36.463 1.00 103.61 ? 134 ARG C NH1 1 ATOM 1037 N NH2 . ARG A 1 134 ? -5.443 -15.825 -35.808 1.00 103.61 ? 134 ARG C NH2 1 ATOM 1038 N N . GLY A 1 135 ? -8.339 -10.541 -34.493 1.00 119.23 ? 135 GLY C N 1 ATOM 1039 C CA . GLY A 1 135 ? -9.313 -10.334 -35.570 1.00 119.23 ? 135 GLY C CA 1 ATOM 1040 C C . GLY A 1 135 ? -9.052 -11.078 -36.891 1.00 119.23 ? 135 GLY C C 1 ATOM 1041 O O . GLY A 1 135 ? -9.854 -10.956 -37.810 1.00 119.23 ? 135 GLY C O 1 ATOM 1042 N N . LYS A 1 136 ? -7.940 -11.819 -37.014 1.00 131.69 ? 136 LYS C N 1 ATOM 1043 C CA . LYS A 1 136 ? -7.725 -12.609 -38.234 1.00 131.69 ? 136 LYS C CA 1 ATOM 1044 C C . LYS A 1 136 ? -8.947 -13.504 -38.094 1.00 131.69 ? 136 LYS C C 1 ATOM 1045 O O . LYS A 1 136 ? -9.131 -14.146 -37.080 1.00 131.69 ? 136 LYS C O 1 ATOM 1046 C CB . LYS A 1 136 ? -6.440 -13.506 -38.155 1.00 70.39 ? 136 LYS C CB 1 ATOM 1047 C CG . LYS A 1 136 ? -6.049 -14.241 -39.555 1.00 70.39 ? 136 LYS C CG 1 ATOM 1048 C CD . LYS A 1 136 ? -4.762 -15.142 -39.487 1.00 70.39 ? 136 LYS C CD 1 ATOM 1049 C CE . LYS A 1 136 ? -3.408 -14.390 -39.465 1.00 70.39 ? 136 LYS C CE 1 ATOM 1050 N NZ . LYS A 1 136 ? -2.990 -13.951 -40.783 1.00 70.39 ? 136 LYS C NZ 1 ATOM 1051 N N . ASN A 1 137 ? -9.738 -13.632 -39.126 1.00 89.09 ? 137 ASN C N 1 ATOM 1052 C CA . ASN A 1 137 ? -10.902 -14.443 -38.972 1.00 89.09 ? 137 ASN C CA 1 ATOM 1053 C C . ASN A 1 137 ? -10.748 -15.839 -39.587 1.00 89.09 ? 137 ASN C C 1 ATOM 1054 O O . ASN A 1 137 ? -10.672 -15.959 -40.815 1.00 89.09 ? 137 ASN C O 1 ATOM 1055 C CB . ASN A 1 137 ? -12.061 -13.678 -39.605 1.00 100.57 ? 137 ASN C CB 1 ATOM 1056 C CG . ASN A 1 137 ? -13.357 -14.413 -39.515 1.00 100.57 ? 137 ASN C CG 1 ATOM 1057 O OD1 . ASN A 1 137 ? -13.694 -15.190 -40.417 1.00 100.57 ? 137 ASN C OD1 1 ATOM 1058 N ND2 . ASN A 1 137 ? -14.126 -14.155 -38.441 1.00 100.57 ? 137 ASN C ND2 1 ATOM 1059 N N . ILE A 1 138 ? -10.872 -16.892 -38.778 1.00 96.11 ? 138 ILE C N 1 ATOM 1060 C CA . ILE A 1 138 ? -10.791 -18.260 -39.294 1.00 96.11 ? 138 ILE C CA 1 ATOM 1061 C C . ILE A 1 138 ? -12.034 -19.029 -39.042 1.00 96.11 ? 138 ILE C C 1 ATOM 1062 O O . ILE A 1 138 ? -12.514 -19.167 -37.919 1.00 96.11 ? 138 ILE C O 1 ATOM 1063 C CB . ILE A 1 138 ? -9.525 -19.132 -38.897 1.00 126.07 ? 138 ILE C CB 1 ATOM 1064 C CG1 . ILE A 1 138 ? -8.237 -18.453 -39.397 1.00 126.07 ? 138 ILE C CG1 1 ATOM 1065 C CG2 . ILE A 1 138 ? -9.724 -20.588 -39.310 1.00 126.07 ? 138 ILE C CG2 1 ATOM 1066 C CD1 . ILE A 1 138 ? -6.909 -19.043 -38.893 1.00 126.07 ? 138 ILE C CD1 1 ATOM 1067 N N . GLN A 1 139 ? -12.553 -19.466 -40.208 1.00 91.42 ? 139 GLN C N 1 ATOM 1068 C CA . GLN A 1 139 ? -13.854 -20.120 -40.433 1.00 91.42 ? 139 GLN C CA 1 ATOM 1069 C C . GLN A 1 139 ? -13.684 -21.636 -40.548 1.00 91.42 ? 139 GLN C C 1 ATOM 1070 O O . GLN A 1 139 ? -13.639 -22.209 -41.608 1.00 91.42 ? 139 GLN C O 1 ATOM 1071 C CB . GLN A 1 139 ? -14.231 -19.546 -41.771 1.00 105.10 ? 139 GLN C CB 1 ATOM 1072 C CG . GLN A 1 139 ? -14.562 -18.071 -41.632 1.00 105.10 ? 139 GLN C CG 1 ATOM 1073 C CD . GLN A 1 139 ? -14.954 -17.402 -42.931 1.00 105.10 ? 139 GLN C CD 1 ATOM 1074 O OE1 . GLN A 1 139 ? -15.660 -17.971 -43.742 1.00 105.10 ? 139 GLN C OE1 1 ATOM 1075 N NE2 . GLN A 1 139 ? -14.419 -16.192 -43.159 1.00 105.10 ? 139 GLN C NE2 1 ATOM 1076 N N . GLY A 1 140 ? -13.648 -22.244 -39.382 1.00 99.49 ? 140 GLY C N 1 ATOM 1077 C CA . GLY A 1 140 ? -13.521 -23.670 -39.144 1.00 99.49 ? 140 GLY C CA 1 ATOM 1078 C C . GLY A 1 140 ? -14.572 -24.571 -39.696 1.00 99.49 ? 140 GLY C C 1 ATOM 1079 O O . GLY A 1 140 ? -14.318 -25.682 -40.161 1.00 99.49 ? 140 GLY C O 1 ATOM 1080 N N . GLY A 1 141 ? -15.783 -24.048 -39.574 1.00 92.08 ? 141 GLY C N 1 ATOM 1081 C CA . GLY A 1 141 ? -16.954 -24.814 -39.882 1.00 92.08 ? 141 GLY C CA 1 ATOM 1082 C C . GLY A 1 141 ? -17.184 -25.727 -38.673 1.00 92.08 ? 141 GLY C C 1 ATOM 1083 O O . GLY A 1 141 ? -17.416 -25.229 -37.568 1.00 92.08 ? 141 GLY C O 1 ATOM 1084 N N . LYS A 1 142 ? -17.170 -27.040 -38.874 1.00 107.20 ? 142 LYS C N 1 ATOM 1085 C CA . LYS A 1 142 ? -17.398 -28.016 -37.814 1.00 107.20 ? 142 LYS C CA 1 ATOM 1086 C C . LYS A 1 142 ? -16.451 -28.043 -36.598 1.00 107.20 ? 142 LYS C C 1 ATOM 1087 O O . LYS A 1 142 ? -16.932 -28.271 -35.497 1.00 107.20 ? 142 LYS C O 1 ATOM 1088 C CB . LYS A 1 142 ? -17.594 -29.351 -38.531 1.00 102.89 ? 142 LYS C CB 1 ATOM 1089 C CG . LYS A 1 142 ? -16.364 -29.947 -39.192 1.00 102.89 ? 142 LYS C CG 1 ATOM 1090 C CD . LYS A 1 142 ? -16.688 -31.281 -39.875 1.00 102.89 ? 142 LYS C CD 1 ATOM 1091 C CE . LYS A 1 142 ? -15.473 -31.890 -40.536 1.00 102.89 ? 142 LYS C CE 1 ATOM 1092 N NZ . LYS A 1 142 ? -14.921 -31.071 -41.660 1.00 102.89 ? 142 LYS C NZ 1 ATOM 1093 N N . THR A 1 143 ? -15.135 -27.868 -36.780 1.00 96.99 ? 143 THR C N 1 ATOM 1094 C CA . THR A 1 143 ? -14.185 -27.689 -35.643 1.00 96.99 ? 143 THR C CA 1 ATOM 1095 C C . THR A 1 143 ? -13.236 -26.620 -36.146 1.00 96.99 ? 143 THR C C 1 ATOM 1096 O O . THR A 1 143 ? -13.124 -26.448 -37.349 1.00 96.99 ? 143 THR C O 1 ATOM 1097 C CB . THR A 1 143 ? -13.298 -28.915 -35.278 1.00 121.13 ? 143 THR C CB 1 ATOM 1098 O OG1 . THR A 1 143 ? -12.491 -29.261 -36.395 1.00 121.13 ? 143 THR C OG1 1 ATOM 1099 C CG2 . THR A 1 143 ? -14.122 -30.111 -34.857 1.00 121.13 ? 143 THR C CG2 1 ATOM 1100 N N . LEU A 1 144 ? -12.600 -25.850 -35.280 1.00 99.29 ? 144 LEU C N 1 ATOM 1101 C CA . LEU A 1 144 ? -11.613 -24.925 -35.816 1.00 99.29 ? 144 LEU C CA 1 ATOM 1102 C C . LEU A 1 144 ? -10.217 -25.217 -35.223 1.00 99.29 ? 144 LEU C C 1 ATOM 1103 O O . LEU A 1 144 ? -10.094 -25.310 -34.010 1.00 99.29 ? 144 LEU C O 1 ATOM 1104 C CB . LEU A 1 144 ? -12.027 -23.464 -35.601 1.00 115.29 ? 144 LEU C CB 1 ATOM 1105 C CG . LEU A 1 144 ? -11.020 -22.455 -36.204 1.00 115.29 ? 144 LEU C CG 1 ATOM 1106 C CD1 . LEU A 1 144 ? -9.837 -22.239 -35.298 1.00 115.29 ? 144 LEU C CD1 1 ATOM 1107 C CD2 . LEU A 1 144 ? -10.496 -22.979 -37.565 1.00 115.29 ? 144 LEU C CD2 1 ATOM 1108 N N . SER A 1 145 ? -9.159 -25.346 -36.037 1.00 101.01 ? 145 SER C N 1 ATOM 1109 C CA . SER A 1 145 ? -7.836 -25.604 -35.435 1.00 101.01 ? 145 SER C CA 1 ATOM 1110 C C . SER A 1 145 ? -6.853 -24.625 -35.938 1.00 101.01 ? 145 SER C C 1 ATOM 1111 O O . SER A 1 145 ? -6.894 -24.288 -37.099 1.00 101.01 ? 145 SER C O 1 ATOM 1112 C CB . SER A 1 145 ? -7.256 -27.003 -35.787 1.00 78.55 ? 145 SER C CB 1 ATOM 1113 O OG . SER A 1 145 ? -7.951 -28.088 -35.166 1.00 78.55 ? 145 SER C OG 1 ATOM 1114 N N . VAL A 1 146 ? -5.983 -24.152 -35.055 1.00 157.49 ? 146 VAL C N 1 ATOM 1115 C CA . VAL A 1 146 ? -4.912 -23.295 -35.506 1.00 157.49 ? 146 VAL C CA 1 ATOM 1116 C C . VAL A 1 146 ? -3.809 -24.323 -35.221 1.00 157.49 ? 146 VAL C C 1 ATOM 1117 O O . VAL A 1 146 ? -3.617 -24.717 -34.077 1.00 157.49 ? 146 VAL C O 1 ATOM 1118 C CB . VAL A 1 146 ? -4.816 -22.034 -34.598 1.00 47.66 ? 146 VAL C CB 1 ATOM 1119 C CG1 . VAL A 1 146 ? -3.668 -21.126 -35.088 1.00 47.66 ? 146 VAL C CG1 1 ATOM 1120 C CG2 . VAL A 1 146 ? -6.144 -21.294 -34.652 1.00 47.66 ? 146 VAL C CG2 1 ATOM 1121 N N . SER A 1 147 ? -3.062 -24.727 -36.241 1.00 98.74 ? 147 SER C N 1 ATOM 1122 C CA . SER A 1 147 ? -2.040 -25.722 -36.056 1.00 98.74 ? 147 SER C CA 1 ATOM 1123 C C . SER A 1 147 ? -0.922 -25.341 -35.101 1.00 98.74 ? 147 SER C C 1 ATOM 1124 O O . SER A 1 147 ? -0.466 -26.194 -34.322 1.00 98.74 ? 147 SER C O 1 ATOM 1125 C CB . SER A 1 147 ? -1.564 -26.159 -37.428 1.00 92.74 ? 147 SER C CB 1 ATOM 1126 O OG . SER A 1 147 ? -1.100 -25.027 -38.122 1.00 92.74 ? 147 SER C OG 1 ATOM 1127 N N . GLN A 1 148 ? -0.462 -24.082 -35.143 1.00 115.13 ? 148 GLN C N 1 ATOM 1128 C CA . GLN A 1 148 ? 0.558 -23.664 -34.172 1.00 115.13 ? 148 GLN C CA 1 ATOM 1129 C C . GLN A 1 148 ? 0.230 -22.271 -33.620 1.00 115.13 ? 148 GLN C C 1 ATOM 1130 O O . GLN A 1 148 ? -0.015 -21.325 -34.352 1.00 115.13 ? 148 GLN C O 1 ATOM 1131 C CB . GLN A 1 148 ? 1.933 -23.650 -34.826 1.00 134.89 ? 148 GLN C CB 1 ATOM 1132 C CG . GLN A 1 148 ? 2.032 -22.645 -35.921 1.00 134.89 ? 148 GLN C CG 1 ATOM 1133 C CD . GLN A 1 148 ? 3.305 -22.768 -36.705 1.00 134.89 ? 148 GLN C CD 1 ATOM 1134 O OE1 . GLN A 1 148 ? 3.764 -23.874 -36.991 1.00 134.89 ? 148 GLN C OE1 1 ATOM 1135 N NE2 . GLN A 1 148 ? 3.890 -21.624 -37.067 1.00 134.89 ? 148 GLN C NE2 1 ATOM 1136 N N . LEU A 1 149 ? 0.332 -22.176 -32.303 1.00 118.27 ? 149 LEU C N 1 ATOM 1137 C CA . LEU A 1 149 ? 0.005 -21.003 -31.501 1.00 118.27 ? 149 LEU C CA 1 ATOM 1138 C C . LEU A 1 149 ? 0.965 -19.815 -31.361 1.00 118.27 ? 149 LEU C C 1 ATOM 1139 O O . LEU A 1 149 ? 2.154 -19.954 -31.555 1.00 118.27 ? 149 LEU C O 1 ATOM 1140 C CB . LEU A 1 149 ? -0.617 -21.538 -30.190 1.00 74.53 ? 149 LEU C CB 1 ATOM 1141 C CG . LEU A 1 149 ? -2.014 -22.129 -30.558 1.00 74.53 ? 149 LEU C CG 1 ATOM 1142 C CD1 . LEU A 1 149 ? -2.685 -22.888 -29.522 1.00 74.53 ? 149 LEU C CD1 1 ATOM 1143 C CD2 . LEU A 1 149 ? -2.900 -20.954 -30.856 1.00 74.53 ? 149 LEU C CD2 1 ATOM 1144 N N . GLU A 1 150 ? 0.413 -18.663 -30.990 1.00 78.98 ? 150 GLU C N 1 ATOM 1145 C CA . GLU A 1 150 ? 1.066 -17.338 -30.918 1.00 78.98 ? 150 GLU C CA 1 ATOM 1146 C C . GLU A 1 150 ? 0.850 -16.379 -29.676 1.00 78.98 ? 150 GLU C C 1 ATOM 1147 O O . GLU A 1 150 ? 0.122 -16.682 -28.716 1.00 78.98 ? 150 GLU C O 1 ATOM 1148 C CB . GLU A 1 150 ? 0.730 -16.575 -32.204 1.00 137.21 ? 150 GLU C CB 1 ATOM 1149 C CG . GLU A 1 150 ? 1.351 -17.193 -33.457 1.00 137.21 ? 150 GLU C CG 1 ATOM 1150 C CD . GLU A 1 150 ? 1.020 -16.438 -34.747 1.00 137.21 ? 150 GLU C CD 1 ATOM 1151 O OE1 . GLU A 1 150 ? 0.155 -15.532 -34.733 1.00 137.21 ? 150 GLU C OE1 1 ATOM 1152 O OE2 . GLU A 1 150 ? 1.558 -16.816 -35.808 1.00 137.21 ? 150 GLU C OE2 1 ATOM 1153 N N . LEU A 1 151 ? 1.743 -15.405 -29.566 1.00 116.84 ? 151 LEU C N 1 ATOM 1154 C CA . LEU A 1 151 ? 1.636 -14.277 -28.603 1.00 116.84 ? 151 LEU C CA 1 ATOM 1155 C C . LEU A 1 151 ? 0.342 -13.390 -28.796 1.00 116.84 ? 151 LEU C C 1 ATOM 1156 O O . LEU A 1 151 ? -0.338 -13.014 -27.849 1.00 116.84 ? 151 LEU C O 1 ATOM 1157 C CB . LEU A 1 151 ? 2.846 -13.343 -28.758 1.00 103.89 ? 151 LEU C CB 1 ATOM 1158 C CG . LEU A 1 151 ? 4.217 -13.824 -28.313 1.00 103.89 ? 151 LEU C CG 1 ATOM 1159 C CD1 . LEU A 1 151 ? 5.256 -12.822 -28.800 1.00 103.89 ? 151 LEU C CD1 1 ATOM 1160 C CD2 . LEU A 1 151 ? 4.231 -14.022 -26.796 1.00 103.89 ? 151 LEU C CD2 1 ATOM 1161 N N . GLN A 1 152 ? 0.021 -13.164 -30.070 1.00 124.01 ? 152 GLN C N 1 ATOM 1162 C CA . GLN A 1 152 ? -1.023 -12.326 -30.714 1.00 124.01 ? 152 GLN C CA 1 ATOM 1163 C C . GLN A 1 152 ? -2.360 -12.853 -30.211 1.00 124.01 ? 152 GLN C C 1 ATOM 1164 O O . GLN A 1 152 ? -3.345 -12.124 -30.053 1.00 124.01 ? 152 GLN C O 1 ATOM 1165 C CB . GLN A 1 152 ? -1.035 -12.539 -32.232 1.00 127.92 ? 152 GLN C CB 1 ATOM 1166 C CG . GLN A 1 152 ? 0.158 -11.988 -32.980 1.00 127.92 ? 152 GLN C CG 1 ATOM 1167 C CD . GLN A 1 152 ? 0.086 -12.308 -34.454 1.00 127.92 ? 152 GLN C CD 1 ATOM 1168 O OE1 . GLN A 1 152 ? -0.766 -13.085 -34.895 1.00 127.92 ? 152 GLN C OE1 1 ATOM 1169 N NE2 . GLN A 1 152 ? 1.027 -11.762 -35.216 1.00 127.92 ? 152 GLN C NE2 1 ATOM 1170 N N . ASP A 1 153 ? -2.381 -14.172 -30.138 1.00 150.49 ? 153 ASP C N 1 ATOM 1171 C CA . ASP A 1 153 ? -3.523 -15.003 -29.833 1.00 150.49 ? 153 ASP C CA 1 ATOM 1172 C C . ASP A 1 153 ? -4.077 -14.971 -28.382 1.00 150.49 ? 153 ASP C C 1 ATOM 1173 O O . ASP A 1 153 ? -5.229 -15.341 -28.182 1.00 150.49 ? 153 ASP C O 1 ATOM 1174 C CB . ASP A 1 153 ? -3.043 -16.427 -30.023 1.00 132.73 ? 153 ASP C CB 1 ATOM 1175 C CG . ASP A 1 153 ? -2.800 -16.758 -31.447 1.00 132.73 ? 153 ASP C CG 1 ATOM 1176 O OD1 . ASP A 1 153 ? -3.341 -16.053 -32.316 1.00 132.73 ? 153 ASP C OD1 1 ATOM 1177 O OD2 . ASP A 1 153 ? -2.046 -17.726 -31.691 1.00 132.73 ? 153 ASP C OD2 1 ATOM 1178 N N . SER A 1 154 ? -3.323 -14.551 -27.370 1.00 151.17 ? 154 SER C N 1 ATOM 1179 C CA . SER A 1 154 ? -3.910 -14.543 -26.019 1.00 151.17 ? 154 SER C CA 1 ATOM 1180 C C . SER A 1 154 ? -4.968 -13.475 -25.890 1.00 151.17 ? 154 SER C C 1 ATOM 1181 O O . SER A 1 154 ? -4.980 -12.491 -26.617 1.00 151.17 ? 154 SER C O 1 ATOM 1182 C CB . SER A 1 154 ? -2.850 -14.444 -24.891 1.00 138.49 ? 154 SER C CB 1 ATOM 1183 O OG . SER A 1 154 ? -2.196 -13.185 -24.809 1.00 138.49 ? 154 SER C OG 1 ATOM 1184 N N . GLY A 1 155 ? -5.821 -13.631 -24.910 1.00 113.93 ? 155 GLY C N 1 ATOM 1185 C CA . GLY A 1 155 ? -6.921 -12.700 -24.779 1.00 113.93 ? 155 GLY C CA 1 ATOM 1186 C C . GLY A 1 155 ? -8.202 -13.422 -25.215 1.00 113.93 ? 155 GLY C C 1 ATOM 1187 O O . GLY A 1 155 ? -8.131 -14.590 -25.628 1.00 113.93 ? 155 GLY C O 1 ATOM 1188 N N . THR A 1 156 ? -9.354 -12.743 -25.175 1.00 95.62 ? 156 THR C N 1 ATOM 1189 C CA . THR A 1 156 ? -10.625 -13.393 -25.461 1.00 95.62 ? 156 THR C CA 1 ATOM 1190 C C . THR A 1 156 ? -11.164 -13.167 -26.859 1.00 95.62 ? 156 THR C C 1 ATOM 1191 O O . THR A 1 156 ? -11.378 -12.045 -27.271 1.00 95.62 ? 156 THR C O 1 ATOM 1192 C CB . THR A 1 156 ? -11.638 -12.923 -24.448 1.00 85.17 ? 156 THR C CB 1 ATOM 1193 O OG1 . THR A 1 156 ? -11.143 -13.217 -23.131 1.00 85.17 ? 156 THR C OG1 1 ATOM 1194 C CG2 . THR A 1 156 ? -13.002 -13.615 -24.673 1.00 85.17 ? 156 THR C CG2 1 ATOM 1195 N N . TRP A 1 157 ? -11.500 -14.243 -27.548 1.00 110.64 ? 157 TRP C N 1 ATOM 1196 C CA . TRP A 1 157 ? -11.940 -14.147 -28.931 1.00 110.64 ? 157 TRP C CA 1 ATOM 1197 C C . TRP A 1 157 ? -13.215 -14.910 -29.126 1.00 110.64 ? 157 TRP C C 1 ATOM 1198 O O . TRP A 1 157 ? -13.513 -15.806 -28.335 1.00 110.64 ? 157 TRP C O 1 ATOM 1199 C CB . TRP A 1 157 ? -10.756 -14.470 -29.880 1.00 103.16 ? 157 TRP C CB 1 ATOM 1200 C CG . TRP A 1 157 ? -10.070 -15.803 -29.824 1.00 103.16 ? 157 TRP C CG 1 ATOM 1201 C CD1 . TRP A 1 157 ? -9.403 -16.315 -28.739 1.00 103.16 ? 157 TRP C CD1 1 ATOM 1202 C CD2 . TRP A 1 157 ? -9.575 -16.556 -30.955 1.00 103.16 ? 157 TRP C CD2 1 ATOM 1203 N NE1 . TRP A 1 157 ? -8.542 -17.307 -29.119 1.00 103.16 ? 157 TRP C NE1 1 ATOM 1204 C CE2 . TRP A 1 157 ? -8.624 -17.474 -30.472 1.00 103.16 ? 157 TRP C CE2 1 ATOM 1205 C CE3 . TRP A 1 157 ? -9.831 -16.527 -32.330 1.00 103.16 ? 157 TRP C CE3 1 ATOM 1206 C CZ2 . TRP A 1 157 ? -7.938 -18.350 -31.313 1.00 103.16 ? 157 TRP C CZ2 1 ATOM 1207 C CZ3 . TRP A 1 157 ? -9.138 -17.396 -33.158 1.00 103.16 ? 157 TRP C CZ3 1 ATOM 1208 C CH2 . TRP A 1 157 ? -8.208 -18.291 -32.649 1.00 103.16 ? 157 TRP C CH2 1 ATOM 1209 N N . THR A 1 158 ? -13.938 -14.579 -30.200 1.00 178.53 ? 158 THR C N 1 ATOM 1210 C CA . THR A 1 158 ? -15.327 -14.995 -30.402 1.00 178.53 ? 158 THR C CA 1 ATOM 1211 C C . THR A 1 158 ? -15.768 -15.832 -31.588 1.00 178.53 ? 158 THR C C 1 ATOM 1212 O O . THR A 1 158 ? -15.474 -15.518 -32.733 1.00 178.53 ? 158 THR C O 1 ATOM 1213 C CB . THR A 1 158 ? -16.182 -13.738 -30.540 1.00 122.58 ? 158 THR C CB 1 ATOM 1214 O OG1 . THR A 1 158 ? -16.074 -12.951 -29.355 1.00 122.58 ? 158 THR C OG1 1 ATOM 1215 C CG2 . THR A 1 158 ? -17.649 -14.106 -30.809 1.00 122.58 ? 158 THR C CG2 1 ATOM 1216 N N . CYS A 1 159 ? -16.501 -16.902 -31.296 1.00 98.55 ? 159 CYS C N 1 ATOM 1217 C CA . CYS A 1 159 ? -17.022 -17.718 -32.377 1.00 98.55 ? 159 CYS C CA 1 ATOM 1218 C C . CYS A 1 159 ? -18.557 -17.555 -32.475 1.00 98.55 ? 159 CYS C C 1 ATOM 1219 O O . CYS A 1 159 ? -19.283 -17.315 -31.499 1.00 98.55 ? 159 CYS C O 1 ATOM 1220 C CB . CYS A 1 159 ? -16.761 -19.216 -32.178 1.00 132.81 ? 159 CYS C CB 1 ATOM 1221 S SG . CYS A 1 159 ? -15.062 -19.783 -32.048 1.00 132.81 ? 159 CYS C SG 1 ATOM 1222 N N . THR A 1 160 ? -18.996 -17.689 -33.724 1.00 114.73 ? 160 THR C N 1 ATOM 1223 C CA . THR A 1 160 ? -20.361 -17.591 -34.179 1.00 114.73 ? 160 THR C CA 1 ATOM 1224 C C . THR A 1 160 ? -20.843 -18.874 -34.842 1.00 114.73 ? 160 THR C C 1 ATOM 1225 O O . THR A 1 160 ? -20.134 -19.432 -35.655 1.00 114.73 ? 160 THR C O 1 ATOM 1226 C CB . THR A 1 160 ? -20.521 -16.407 -35.100 1.00 82.09 ? 160 THR C CB 1 ATOM 1227 O OG1 . THR A 1 160 ? -20.171 -15.207 -34.394 1.00 82.09 ? 160 THR C OG1 1 ATOM 1228 C CG2 . THR A 1 160 ? -21.928 -16.319 -35.557 1.00 82.09 ? 160 THR C CG2 1 ATOM 1229 N N . VAL A 1 161 ? -21.997 -19.380 -34.438 1.00 105.33 ? 161 VAL C N 1 ATOM 1230 C CA . VAL A 1 161 ? -22.577 -20.588 -35.021 1.00 105.33 ? 161 VAL C CA 1 ATOM 1231 C C . VAL A 1 161 ? -23.891 -20.199 -35.653 1.00 105.33 ? 161 VAL C C 1 ATOM 1232 O O . VAL A 1 161 ? -24.720 -19.597 -34.997 1.00 105.33 ? 161 VAL C O 1 ATOM 1233 C CB . VAL A 1 161 ? -22.806 -21.652 -33.901 1.00 72.86 ? 161 VAL C CB 1 ATOM 1234 C CG1 . VAL A 1 161 ? -23.406 -22.930 -34.419 1.00 72.86 ? 161 VAL C CG1 1 ATOM 1235 C CG2 . VAL A 1 161 ? -21.436 -22.063 -33.397 1.00 72.86 ? 161 VAL C CG2 1 ATOM 1236 N N . LEU A 1 162 ? -24.100 -20.587 -36.913 1.00 110.30 ? 162 LEU C N 1 ATOM 1237 C CA . LEU A 1 162 ? -25.321 -20.216 -37.608 1.00 110.30 ? 162 LEU C CA 1 ATOM 1238 C C . LEU A 1 162 ? -26.349 -21.302 -38.014 1.00 110.30 ? 162 LEU C C 1 ATOM 1239 O O . LEU A 1 162 ? -26.011 -22.259 -38.738 1.00 110.30 ? 162 LEU C O 1 ATOM 1240 C CB . LEU A 1 162 ? -24.897 -19.369 -38.819 1.00 117.80 ? 162 LEU C CB 1 ATOM 1241 C CG . LEU A 1 162 ? -25.850 -18.755 -39.845 1.00 117.80 ? 162 LEU C CG 1 ATOM 1242 C CD1 . LEU A 1 162 ? -25.194 -17.492 -40.349 1.00 117.80 ? 162 LEU C CD1 1 ATOM 1243 C CD2 . LEU A 1 162 ? -26.143 -19.717 -41.022 1.00 117.80 ? 162 LEU C CD2 1 ATOM 1244 N N . GLN A 1 163 ? -27.583 -21.161 -37.488 1.00 148.03 ? 163 GLN C N 1 ATOM 1245 C CA . GLN A 1 163 ? -28.722 -22.028 -37.824 1.00 148.03 ? 163 GLN C CA 1 ATOM 1246 C C . GLN A 1 163 ? -30.032 -21.260 -37.966 1.00 148.03 ? 163 GLN C C 1 ATOM 1247 O O . GLN A 1 163 ? -30.287 -20.307 -37.221 1.00 148.03 ? 163 GLN C O 1 ATOM 1248 C CB . GLN A 1 163 ? -28.999 -23.056 -36.736 1.00 90.84 ? 163 GLN C CB 1 ATOM 1249 C CG . GLN A 1 163 ? -27.989 -24.118 -36.585 1.00 90.84 ? 163 GLN C CG 1 ATOM 1250 C CD . GLN A 1 163 ? -27.881 -24.996 -37.774 1.00 90.84 ? 163 GLN C CD 1 ATOM 1251 O OE1 . GLN A 1 163 ? -27.394 -24.560 -38.821 1.00 90.84 ? 163 GLN C OE1 1 ATOM 1252 N NE2 . GLN A 1 163 ? -28.310 -26.249 -37.637 1.00 90.84 ? 163 GLN C NE2 1 ATOM 1253 N N . ASN A 1 164 ? -30.844 -21.664 -38.933 1.00 195.55 ? 164 ASN C N 1 ATOM 1254 C CA . ASN A 1 164 ? -32.202 -21.156 -39.125 1.00 195.55 ? 164 ASN C CA 1 ATOM 1255 C C . ASN A 1 164 ? -32.092 -19.636 -39.106 1.00 195.55 ? 164 ASN C C 1 ATOM 1256 O O . ASN A 1 164 ? -32.952 -18.907 -38.590 1.00 195.55 ? 164 ASN C O 1 ATOM 1257 C CB . ASN A 1 164 ? -33.087 -21.713 -38.004 1.00 175.08 ? 164 ASN C CB 1 ATOM 1258 C CG . ASN A 1 164 ? -33.324 -23.218 -38.159 1.00 175.08 ? 164 ASN C CG 1 ATOM 1259 O OD1 . ASN A 1 164 ? -33.173 -23.762 -39.244 1.00 175.08 ? 164 ASN C OD1 1 ATOM 1260 N ND2 . ASN A 1 164 ? -33.660 -23.892 -37.070 1.00 175.08 ? 164 ASN C ND2 1 ATOM 1261 N N . GLN A 1 165 ? -31.017 -19.209 -39.749 1.00 152.32 ? 165 GLN C N 1 ATOM 1262 C CA . GLN A 1 165 ? -30.583 -17.839 -39.946 1.00 152.32 ? 165 GLN C CA 1 ATOM 1263 C C . GLN A 1 165 ? -30.512 -16.952 -38.670 1.00 152.32 ? 165 GLN C C 1 ATOM 1264 O O . GLN A 1 165 ? -30.859 -15.772 -38.676 1.00 152.32 ? 165 GLN C O 1 ATOM 1265 C CB . GLN A 1 165 ? -31.436 -17.243 -41.060 1.00 132.86 ? 165 GLN C CB 1 ATOM 1266 C CG . GLN A 1 165 ? -31.057 -17.899 -42.411 1.00 132.86 ? 165 GLN C CG 1 ATOM 1267 C CD . GLN A 1 165 ? -29.609 -17.719 -42.833 1.00 132.86 ? 165 GLN C CD 1 ATOM 1268 O OE1 . GLN A 1 165 ? -29.088 -16.604 -42.831 1.00 132.86 ? 165 GLN C OE1 1 ATOM 1269 N NE2 . GLN A 1 165 ? -28.940 -18.829 -43.157 1.00 132.86 ? 165 GLN C NE2 1 ATOM 1270 N N . LYS A 1 166 ? -30.039 -17.559 -37.586 1.00 152.61 ? 166 LYS C N 1 ATOM 1271 C CA . LYS A 1 166 ? -29.776 -16.906 -36.304 1.00 152.61 ? 166 LYS C CA 1 ATOM 1272 C C . LYS A 1 166 ? -28.356 -17.190 -35.890 1.00 152.61 ? 166 LYS C C 1 ATOM 1273 O O . LYS A 1 166 ? -27.848 -18.253 -36.203 1.00 152.61 ? 166 LYS C O 1 ATOM 1274 C CB . LYS A 1 166 ? -30.725 -17.370 -35.221 1.00 94.74 ? 166 LYS C CB 1 ATOM 1275 C CG . LYS A 1 166 ? -32.125 -16.934 -35.468 1.00 94.74 ? 166 LYS C CG 1 ATOM 1276 C CD . LYS A 1 166 ? -32.140 -15.417 -35.268 1.00 94.74 ? 166 LYS C CD 1 ATOM 1277 C CE . LYS A 1 166 ? -33.529 -14.874 -35.292 1.00 94.74 ? 166 LYS C CE 1 ATOM 1278 N NZ . LYS A 1 166 ? -34.337 -15.564 -34.234 1.00 94.74 ? 166 LYS C NZ 1 ATOM 1279 N N . LYS A 1 167 ? -27.702 -16.256 -35.203 1.00 110.05 ? 167 LYS C N 1 ATOM 1280 C CA . LYS A 1 167 ? -26.315 -16.487 -34.813 1.00 110.05 ? 167 LYS C CA 1 ATOM 1281 C C . LYS A 1 167 ? -26.193 -16.439 -33.286 1.00 110.05 ? 167 LYS C C 1 ATOM 1282 O O . LYS A 1 167 ? -26.879 -15.667 -32.634 1.00 110.05 ? 167 LYS C O 1 ATOM 1283 C CB . LYS A 1 167 ? -25.343 -15.485 -35.508 1.00 79.07 ? 167 LYS C CB 1 ATOM 1284 C CG . LYS A 1 167 ? -25.214 -15.692 -37.042 1.00 79.07 ? 167 LYS C CG 1 ATOM 1285 C CD . LYS A 1 167 ? -24.263 -14.733 -37.811 1.00 79.07 ? 167 LYS C CD 1 ATOM 1286 C CE . LYS A 1 167 ? -24.566 -13.229 -37.762 1.00 79.07 ? 167 LYS C CE 1 ATOM 1287 N NZ . LYS A 1 167 ? -24.404 -12.677 -36.358 1.00 79.07 ? 167 LYS C NZ 1 ATOM 1288 N N . VAL A 1 168 ? -25.332 -17.270 -32.716 1.00 123.93 ? 168 VAL C N 1 ATOM 1289 C CA . VAL A 1 168 ? -25.163 -17.308 -31.277 1.00 123.93 ? 168 VAL C CA 1 ATOM 1290 C C . VAL A 1 168 ? -23.651 -17.213 -31.012 1.00 123.93 ? 168 VAL C C 1 ATOM 1291 O O . VAL A 1 168 ? -22.832 -17.744 -31.772 1.00 123.93 ? 168 VAL C O 1 ATOM 1292 C CB . VAL A 1 168 ? -25.790 -18.581 -30.670 1.00 89.46 ? 168 VAL C CB 1 ATOM 1293 C CG1 . VAL A 1 168 ? -25.007 -19.796 -31.053 1.00 89.46 ? 168 VAL C CG1 1 ATOM 1294 C CG2 . VAL A 1 168 ? -25.878 -18.433 -29.200 1.00 89.46 ? 168 VAL C CG2 1 ATOM 1295 N N . GLU A 1 169 ? -23.295 -16.446 -29.976 1.00 119.81 ? 169 GLU C N 1 ATOM 1296 C CA . GLU A 1 169 ? -21.899 -16.158 -29.629 1.00 119.81 ? 169 GLU C CA 1 ATOM 1297 C C . GLU A 1 169 ? -21.246 -16.949 -28.481 1.00 119.81 ? 169 GLU C C 1 ATOM 1298 O O . GLU A 1 169 ? -21.699 -16.952 -27.363 1.00 119.81 ? 169 GLU C O 1 ATOM 1299 C CB . GLU A 1 169 ? -21.835 -14.659 -29.287 1.00 131.89 ? 169 GLU C CB 1 ATOM 1300 C CG . GLU A 1 169 ? -20.503 -14.091 -28.892 1.00 131.89 ? 169 GLU C CG 1 ATOM 1301 C CD . GLU A 1 169 ? -20.564 -12.598 -28.576 1.00 131.89 ? 169 GLU C CD 1 ATOM 1302 O OE1 . GLU A 1 169 ? -21.619 -11.979 -28.765 1.00 131.89 ? 169 GLU C OE1 1 ATOM 1303 O OE2 . GLU A 1 169 ? -19.528 -12.011 -28.206 1.00 131.89 ? 169 GLU C OE2 1 ATOM 1304 N N . PHE A 1 170 ? -20.130 -17.584 -28.750 1.00 87.11 ? 170 PHE C N 1 ATOM 1305 C CA . PHE A 1 170 ? -19.429 -18.217 -27.668 1.00 87.11 ? 170 PHE C CA 1 ATOM 1306 C C . PHE A 1 170 ? -18.124 -17.440 -27.794 1.00 87.11 ? 170 PHE C C 1 ATOM 1307 O O . PHE A 1 170 ? -17.581 -17.213 -28.886 1.00 87.11 ? 170 PHE C O 1 ATOM 1308 C CB . PHE A 1 170 ? -19.113 -19.696 -27.912 1.00 85.06 ? 170 PHE C CB 1 ATOM 1309 C CG . PHE A 1 170 ? -20.266 -20.584 -27.898 1.00 85.06 ? 170 PHE C CG 1 ATOM 1310 C CD1 . PHE A 1 170 ? -20.650 -21.149 -26.720 1.00 85.06 ? 170 PHE C CD1 1 ATOM 1311 C CD2 . PHE A 1 170 ? -20.960 -20.885 -29.036 1.00 85.06 ? 170 PHE C CD2 1 ATOM 1312 C CE1 . PHE A 1 170 ? -21.724 -22.016 -26.667 1.00 85.06 ? 170 PHE C CE1 1 ATOM 1313 C CE2 . PHE A 1 170 ? -22.054 -21.757 -29.012 1.00 85.06 ? 170 PHE C CE2 1 ATOM 1314 C CZ . PHE A 1 170 ? -22.435 -22.321 -27.836 1.00 85.06 ? 170 PHE C CZ 1 ATOM 1315 N N . LYS A 1 171 ? -17.571 -17.095 -26.653 1.00 102.09 ? 171 LYS C N 1 ATOM 1316 C CA . LYS A 1 171 ? -16.356 -16.373 -26.696 1.00 102.09 ? 171 LYS C CA 1 ATOM 1317 C C . LYS A 1 171 ? -15.545 -17.195 -25.734 1.00 102.09 ? 171 LYS C C 1 ATOM 1318 O O . LYS A 1 171 ? -16.013 -17.616 -24.678 1.00 102.09 ? 171 LYS C O 1 ATOM 1319 C CB . LYS A 1 171 ? -16.653 -14.917 -26.249 1.00 81.33 ? 171 LYS C CB 1 ATOM 1320 C CG . LYS A 1 171 ? -17.162 -14.669 -24.818 1.00 81.33 ? 171 LYS C CG 1 ATOM 1321 C CD . LYS A 1 171 ? -17.402 -13.134 -24.622 1.00 81.33 ? 171 LYS C CD 1 ATOM 1322 C CE . LYS A 1 171 ? -17.918 -12.773 -23.207 1.00 81.33 ? 171 LYS C CE 1 ATOM 1323 N NZ . LYS A 1 171 ? -19.408 -13.013 -22.982 1.00 81.33 ? 171 LYS C NZ 1 ATOM 1324 N N . ILE A 1 172 ? -14.288 -17.360 -26.100 1.00 99.46 ? 172 ILE C N 1 ATOM 1325 C CA . ILE A 1 172 ? -13.358 -18.142 -25.329 1.00 99.46 ? 172 ILE C CA 1 ATOM 1326 C C . ILE A 1 172 ? -12.200 -17.283 -24.891 1.00 99.46 ? 172 ILE C C 1 ATOM 1327 O O . ILE A 1 172 ? -11.557 -16.594 -25.689 1.00 99.46 ? 172 ILE C O 1 ATOM 1328 C CB . ILE A 1 172 ? -12.821 -19.351 -26.107 1.00 116.71 ? 172 ILE C CB 1 ATOM 1329 C CG1 . ILE A 1 172 ? -13.965 -20.269 -26.512 1.00 116.71 ? 172 ILE C CG1 1 ATOM 1330 C CG2 . ILE A 1 172 ? -11.793 -20.095 -25.253 1.00 116.71 ? 172 ILE C CG2 1 ATOM 1331 C CD1 . ILE A 1 172 ? -14.717 -20.781 -25.322 1.00 116.71 ? 172 ILE C CD1 1 ATOM 1332 N N . ASP A 1 173 ? -11.974 -17.313 -23.589 1.00 80.31 ? 173 ASP C N 1 ATOM 1333 C CA . ASP A 1 173 ? -10.942 -16.526 -22.970 1.00 80.31 ? 173 ASP C CA 1 ATOM 1334 C C . ASP A 1 173 ? -9.657 -17.313 -23.223 1.00 80.31 ? 173 ASP C C 1 ATOM 1335 O O . ASP A 1 173 ? -9.682 -18.547 -23.261 1.00 80.31 ? 173 ASP C O 1 ATOM 1336 C CB . ASP A 1 173 ? -11.283 -16.465 -21.471 1.00 125.03 ? 173 ASP C CB 1 ATOM 1337 C CG . ASP A 1 173 ? -12.534 -15.604 -21.172 1.00 125.03 ? 173 ASP C CG 1 ATOM 1338 O OD1 . ASP A 1 173 ? -12.826 -14.645 -21.901 1.00 125.03 ? 173 ASP C OD1 1 ATOM 1339 O OD2 . ASP A 1 173 ? -13.273 -15.922 -20.222 1.00 125.03 ? 173 ASP C OD2 1 ATOM 1340 N N . ILE A 1 174 ? -8.605 -16.600 -23.618 1.00 97.32 ? 174 ILE C N 1 ATOM 1341 C CA . ILE A 1 174 ? -7.230 -17.115 -23.756 1.00 97.32 ? 174 ILE C CA 1 ATOM 1342 C C . ILE A 1 174 ? -5.935 -16.674 -23.056 1.00 97.32 ? 174 ILE C C 1 ATOM 1343 O O . ILE A 1 174 ? -5.516 -15.524 -23.094 1.00 97.32 ? 174 ILE C O 1 ATOM 1344 C CB . ILE A 1 174 ? -6.862 -17.566 -25.181 1.00 53.87 ? 174 ILE C CB 1 ATOM 1345 C CG1 . ILE A 1 174 ? -7.740 -18.782 -25.579 1.00 53.87 ? 174 ILE C CG1 1 ATOM 1346 C CG2 . ILE A 1 174 ? -5.388 -17.540 -25.370 1.00 53.87 ? 174 ILE C CG2 1 ATOM 1347 C CD1 . ILE A 1 174 ? -7.649 -19.198 -27.082 1.00 53.87 ? 174 ILE C CD1 1 ATOM 1348 N N . VAL A 1 175 ? -5.271 -17.674 -22.487 1.00 109.82 ? 175 VAL C N 1 ATOM 1349 C CA . VAL A 1 175 ? -4.029 -17.537 -21.747 1.00 109.82 ? 175 VAL C CA 1 ATOM 1350 C C . VAL A 1 175 ? -2.979 -18.239 -22.603 1.00 109.82 ? 175 VAL C C 1 ATOM 1351 O O . VAL A 1 175 ? -3.089 -19.448 -22.830 1.00 109.82 ? 175 VAL C O 1 ATOM 1352 C CB . VAL A 1 175 ? -4.149 -18.309 -20.423 1.00 128.51 ? 175 VAL C CB 1 ATOM 1353 C CG1 . VAL A 1 175 ? -2.867 -18.190 -19.619 1.00 128.51 ? 175 VAL C CG1 1 ATOM 1354 C CG2 . VAL A 1 175 ? -5.368 -17.834 -19.656 1.00 128.51 ? 175 VAL C CG2 1 ATOM 1355 N N . VAL A 1 176 ? -1.928 -17.521 -23.012 1.00 125.23 ? 176 VAL C N 1 ATOM 1356 C CA . VAL A 1 176 ? -0.868 -18.094 -23.875 1.00 125.23 ? 176 VAL C CA 1 ATOM 1357 C C . VAL A 1 176 ? 0.607 -18.178 -23.334 1.00 125.23 ? 176 VAL C C 1 ATOM 1358 O O . VAL A 1 176 ? 0.971 -17.517 -22.324 1.00 125.23 ? 176 VAL C O 1 ATOM 1359 C CB . VAL A 1 176 ? -0.889 -17.339 -25.234 1.00 70.94 ? 176 VAL C CB 1 ATOM 1360 C CG1 . VAL A 1 176 ? 0.203 -17.807 -26.153 1.00 70.94 ? 176 VAL C CG1 1 ATOM 1361 C CG2 . VAL A 1 176 ? -2.209 -17.546 -25.883 1.00 70.94 ? 176 VAL C CG2 1 ATOM 1362 N N . LEU B 2 4 ? -91.896 -28.059 -14.499 1.00 76.25 ? 85 LEU G N 1 ATOM 1363 C CA . LEU B 2 4 ? -90.514 -28.602 -14.508 1.00 76.25 ? 85 LEU G CA 1 ATOM 1364 C C . LEU B 2 4 ? -90.558 -29.693 -15.590 1.00 76.25 ? 85 LEU G C 1 ATOM 1365 O O . LEU B 2 4 ? -90.118 -30.827 -15.323 1.00 76.25 ? 85 LEU G O 1 ATOM 1366 C CB . LEU B 2 4 ? -90.161 -29.258 -13.157 1.00 82.76 ? 85 LEU G CB 1 ATOM 1367 C CG . LEU B 2 4 ? -90.185 -28.431 -11.832 1.00 82.76 ? 85 LEU G CG 1 ATOM 1368 C CD1 . LEU B 2 4 ? -89.789 -29.352 -10.650 1.00 82.76 ? 85 LEU G CD1 1 ATOM 1369 C CD2 . LEU B 2 4 ? -89.321 -27.195 -11.866 1.00 82.76 ? 85 LEU G CD2 1 ATOM 1370 N N . GLU B 2 5 ? -91.016 -29.311 -16.806 1.00 152.58 ? 86 GLU G N 1 ATOM 1371 C CA . GLU B 2 5 ? -91.216 -30.221 -17.967 1.00 152.58 ? 86 GLU G CA 1 ATOM 1372 C C . GLU B 2 5 ? -89.987 -30.589 -18.769 1.00 152.58 ? 86 GLU G C 1 ATOM 1373 O O . GLU B 2 5 ? -88.981 -29.864 -18.782 1.00 152.58 ? 86 GLU G O 1 ATOM 1374 C CB . GLU B 2 5 ? -92.195 -29.680 -19.046 1.00 136.05 ? 86 GLU G CB 1 ATOM 1375 C CG . GLU B 2 5 ? -93.685 -29.576 -18.757 1.00 136.05 ? 86 GLU G CG 1 ATOM 1376 C CD . GLU B 2 5 ? -94.053 -28.357 -17.951 1.00 136.05 ? 86 GLU G CD 1 ATOM 1377 O OE1 . GLU B 2 5 ? -93.181 -27.475 -17.766 1.00 136.05 ? 86 GLU G OE1 1 ATOM 1378 O OE2 . GLU B 2 5 ? -95.228 -28.274 -17.527 1.00 136.05 ? 86 GLU G OE2 1 ATOM 1379 N N . ASN B 2 6 ? -90.102 -31.729 -19.462 1.00 173.31 ? 87 ASN G N 1 ATOM 1380 C CA . ASN B 2 6 ? -89.003 -32.204 -20.282 1.00 173.31 ? 87 ASN G CA 1 ATOM 1381 C C . ASN B 2 6 ? -88.803 -31.318 -21.522 1.00 173.31 ? 87 ASN G C 1 ATOM 1382 O O . ASN B 2 6 ? -89.715 -31.040 -22.314 1.00 173.31 ? 87 ASN G O 1 ATOM 1383 C CB . ASN B 2 6 ? -89.317 -33.638 -20.718 1.00 127.79 ? 87 ASN G CB 1 ATOM 1384 C CG . ASN B 2 6 ? -90.535 -33.712 -21.612 1.00 127.79 ? 87 ASN G CG 1 ATOM 1385 O OD1 . ASN B 2 6 ? -91.359 -32.808 -21.619 1.00 127.79 ? 87 ASN G OD1 1 ATOM 1386 N ND2 . ASN B 2 6 ? -90.640 -34.777 -22.385 1.00 127.79 ? 87 ASN G ND2 1 ATOM 1387 N N . VAL B 2 7 ? -87.544 -30.929 -21.650 1.00 164.18 ? 88 VAL G N 1 ATOM 1388 C CA . VAL B 2 7 ? -86.969 -30.071 -22.664 1.00 164.18 ? 88 VAL G CA 1 ATOM 1389 C C . VAL B 2 7 ? -85.510 -30.434 -22.921 1.00 164.18 ? 88 VAL G C 1 ATOM 1390 O O . VAL B 2 7 ? -84.847 -30.914 -21.994 1.00 164.18 ? 88 VAL G O 1 ATOM 1391 C CB . VAL B 2 7 ? -87.102 -28.589 -22.286 1.00 86.76 ? 88 VAL G CB 1 ATOM 1392 C CG1 . VAL B 2 7 ? -86.560 -28.358 -20.845 1.00 86.76 ? 88 VAL G CG1 1 ATOM 1393 C CG2 . VAL B 2 7 ? -86.353 -27.735 -23.329 1.00 86.76 ? 88 VAL G CG2 1 ATOM 1394 N N . ILE B 2 8 ? -84.987 -30.234 -24.126 1.00 188.20 ? 89 ILE G N 1 ATOM 1395 C CA . ILE B 2 8 ? -83.553 -30.501 -24.294 1.00 188.20 ? 89 ILE G CA 1 ATOM 1396 C C . ILE B 2 8 ? -82.655 -29.338 -24.738 1.00 188.20 ? 89 ILE G C 1 ATOM 1397 O O . ILE B 2 8 ? -82.738 -28.759 -25.828 1.00 188.20 ? 89 ILE G O 1 ATOM 1398 C CB . ILE B 2 8 ? -83.266 -31.712 -25.270 1.00 124.17 ? 89 ILE G CB 1 ATOM 1399 C CG1 . ILE B 2 8 ? -83.912 -32.991 -24.726 1.00 124.17 ? 89 ILE G CG1 1 ATOM 1400 C CG2 . ILE B 2 8 ? -81.817 -31.718 -25.707 1.00 124.17 ? 89 ILE G CG2 1 ATOM 1401 C CD1 . ILE B 2 8 ? -83.886 -34.157 -25.689 1.00 124.17 ? 89 ILE G CD1 1 ATOM 1402 N N . GLU B 2 9 ? -81.726 -29.136 -23.787 1.00 189.67 ? 90 GLU G N 1 ATOM 1403 C CA . GLU B 2 9 ? -80.634 -28.153 -23.667 1.00 189.67 ? 90 GLU G CA 1 ATOM 1404 C C . GLU B 2 9 ? -79.308 -28.779 -23.338 1.00 189.67 ? 90 GLU G C 1 ATOM 1405 O O . GLU B 2 9 ? -79.228 -29.892 -22.795 1.00 189.67 ? 90 GLU G O 1 ATOM 1406 C CB . GLU B 2 9 ? -80.861 -27.108 -22.556 1.00 123.84 ? 90 GLU G CB 1 ATOM 1407 C CG . GLU B 2 9 ? -81.927 -26.078 -22.737 1.00 123.84 ? 90 GLU G CG 1 ATOM 1408 C CD . GLU B 2 9 ? -81.524 -25.096 -23.825 1.00 123.84 ? 90 GLU G CD 1 ATOM 1409 O OE1 . GLU B 2 9 ? -82.228 -24.957 -24.845 1.00 123.84 ? 90 GLU G OE1 1 ATOM 1410 O OE2 . GLU B 2 9 ? -80.461 -24.467 -23.658 1.00 123.84 ? 90 GLU G OE2 1 ATOM 1411 N N . ASN B 2 10 ? -78.264 -28.012 -23.637 1.00 118.03 ? 91 ASN G N 1 ATOM 1412 C CA . ASN B 2 10 ? -76.904 -28.448 -23.392 1.00 118.03 ? 91 ASN G CA 1 ATOM 1413 C C . ASN B 2 10 ? -76.404 -27.624 -22.201 1.00 118.03 ? 91 ASN G C 1 ATOM 1414 O O . ASN B 2 10 ? -76.594 -26.399 -22.147 1.00 118.03 ? 91 ASN G O 1 ATOM 1415 C CB . ASN B 2 10 ? -76.014 -28.151 -24.610 1.00 87.73 ? 91 ASN G CB 1 ATOM 1416 C CG . ASN B 2 10 ? -76.342 -29.039 -25.817 1.00 87.73 ? 91 ASN G CG 1 ATOM 1417 O OD1 . ASN B 2 10 ? -75.839 -28.815 -26.916 1.00 87.73 ? 91 ASN G OD1 1 ATOM 1418 N ND2 . ASN B 2 10 ? -77.214 -30.022 -25.622 1.00 87.73 ? 91 ASN G ND2 1 ATOM 1419 N N . PHE B 2 11 ? -75.752 -28.309 -21.265 1.00 164.38 ? 92 PHE G N 1 ATOM 1420 C CA . PHE B 2 11 ? -75.155 -27.672 -20.099 1.00 164.38 ? 92 PHE G CA 1 ATOM 1421 C C . PHE B 2 11 ? -73.717 -28.046 -20.281 1.00 164.38 ? 92 PHE G C 1 ATOM 1422 O O . PHE B 2 11 ? -73.390 -29.156 -20.692 1.00 164.38 ? 92 PHE G O 1 ATOM 1423 C CB . PHE B 2 11 ? -75.525 -28.290 -18.724 1.00 119.86 ? 92 PHE G CB 1 ATOM 1424 C CG . PHE B 2 11 ? -76.947 -28.097 -18.246 1.00 119.86 ? 92 PHE G CG 1 ATOM 1425 C CD1 . PHE B 2 11 ? -77.247 -26.976 -17.481 1.00 119.86 ? 92 PHE G CD1 1 ATOM 1426 C CD2 . PHE B 2 11 ? -77.931 -29.090 -18.372 1.00 119.86 ? 92 PHE G CD2 1 ATOM 1427 C CE1 . PHE B 2 11 ? -78.499 -26.851 -16.836 1.00 119.86 ? 92 PHE G CE1 1 ATOM 1428 C CE2 . PHE B 2 11 ? -79.209 -28.963 -17.715 1.00 119.86 ? 92 PHE G CE2 1 ATOM 1429 C CZ . PHE B 2 11 ? -79.484 -27.851 -16.952 1.00 119.86 ? 92 PHE G CZ 1 ATOM 1430 N N . ASN B 2 12 ? -72.875 -27.073 -19.983 1.00 115.97 ? 93 ASN G N 1 ATOM 1431 C CA . ASN B 2 12 ? -71.437 -27.203 -20.018 1.00 115.97 ? 93 ASN G CA 1 ATOM 1432 C C . ASN B 2 12 ? -71.007 -26.643 -18.683 1.00 115.97 ? 93 ASN G C 1 ATOM 1433 O O . ASN B 2 12 ? -71.079 -25.445 -18.433 1.00 115.97 ? 93 ASN G O 1 ATOM 1434 C CB . ASN B 2 12 ? -70.884 -26.382 -21.200 1.00 76.07 ? 93 ASN G CB 1 ATOM 1435 C CG . ASN B 2 12 ? -69.404 -26.456 -21.313 1.00 76.07 ? 93 ASN G CG 1 ATOM 1436 O OD1 . ASN B 2 12 ? -68.712 -26.588 -20.306 1.00 76.07 ? 93 ASN G OD1 1 ATOM 1437 N ND2 . ASN B 2 12 ? -68.900 -26.378 -22.525 1.00 76.07 ? 93 ASN G ND2 1 ATOM 1438 N N . MET B 2 13 ? -70.538 -27.532 -17.830 1.00 121.66 ? 94 MET G N 1 ATOM 1439 C CA . MET B 2 13 ? -70.077 -27.155 -16.515 1.00 121.66 ? 94 MET G CA 1 ATOM 1440 C C . MET B 2 13 ? -68.794 -26.371 -16.600 1.00 121.66 ? 94 MET G C 1 ATOM 1441 O O . MET B 2 13 ? -68.516 -25.481 -15.776 1.00 121.66 ? 94 MET G O 1 ATOM 1442 C CB . MET B 2 13 ? -69.886 -28.383 -15.620 1.00 92.43 ? 94 MET G CB 1 ATOM 1443 C CG . MET B 2 13 ? -68.725 -29.291 -15.982 1.00 92.43 ? 94 MET G CG 1 ATOM 1444 S SD . MET B 2 13 ? -68.541 -30.730 -14.896 1.00 92.43 ? 94 MET G SD 1 ATOM 1445 C CE . MET B 2 13 ? -67.785 -29.949 -13.325 1.00 92.43 ? 94 MET G CE 1 ATOM 1446 N N . TRP B 2 14 ? -68.047 -26.695 -17.654 1.00 96.95 ? 95 TRP G N 1 ATOM 1447 C CA . TRP B 2 14 ? -66.707 -26.182 -17.903 1.00 96.95 ? 95 TRP G CA 1 ATOM 1448 C C . TRP B 2 14 ? -66.854 -24.682 -18.261 1.00 96.95 ? 95 TRP G C 1 ATOM 1449 O O . TRP B 2 14 ? -65.998 -23.857 -17.888 1.00 96.95 ? 95 TRP G O 1 ATOM 1450 C CB . TRP B 2 14 ? -66.064 -27.087 -18.953 1.00 101.31 ? 95 TRP G CB 1 ATOM 1451 C CG . TRP B 2 14 ? -65.796 -28.451 -18.267 1.00 101.31 ? 95 TRP G CG 1 ATOM 1452 C CD1 . TRP B 2 14 ? -66.574 -29.581 -18.381 1.00 101.31 ? 95 TRP G CD1 1 ATOM 1453 C CD2 . TRP B 2 14 ? -64.860 -28.740 -17.209 1.00 101.31 ? 95 TRP G CD2 1 ATOM 1454 N NE1 . TRP B 2 14 ? -66.193 -30.534 -17.465 1.00 101.31 ? 95 TRP G NE1 1 ATOM 1455 C CE2 . TRP B 2 14 ? -65.145 -30.041 -16.737 1.00 101.31 ? 95 TRP G CE2 1 ATOM 1456 C CE3 . TRP B 2 14 ? -63.818 -28.023 -16.610 1.00 101.31 ? 95 TRP G CE3 1 ATOM 1457 C CZ2 . TRP B 2 14 ? -64.432 -30.622 -15.713 1.00 101.31 ? 95 TRP G CZ2 1 ATOM 1458 C CZ3 . TRP B 2 14 ? -63.119 -28.604 -15.598 1.00 101.31 ? 95 TRP G CZ3 1 ATOM 1459 C CH2 . TRP B 2 14 ? -63.426 -29.888 -15.157 1.00 101.31 ? 95 TRP G CH2 1 ATOM 1460 N N . LYS B 2 15 ? -67.904 -24.329 -19.011 1.00 70.99 ? 96 LYS G N 1 ATOM 1461 C CA . LYS B 2 15 ? -68.202 -22.902 -19.235 1.00 70.99 ? 96 LYS G CA 1 ATOM 1462 C C . LYS B 2 15 ? -69.354 -22.271 -18.423 1.00 70.99 ? 96 LYS G C 1 ATOM 1463 O O . LYS B 2 15 ? -70.065 -21.402 -18.972 1.00 70.99 ? 96 LYS G O 1 ATOM 1464 C CB . LYS B 2 15 ? -68.296 -22.400 -20.662 1.00 71.04 ? 96 LYS G CB 1 ATOM 1465 C CG . LYS B 2 15 ? -66.960 -22.392 -21.362 1.00 71.04 ? 96 LYS G CG 1 ATOM 1466 C CD . LYS B 2 15 ? -67.164 -21.875 -22.782 1.00 71.04 ? 96 LYS G CD 1 ATOM 1467 C CE . LYS B 2 15 ? -65.882 -21.800 -23.710 1.00 71.04 ? 96 LYS G CE 1 ATOM 1468 N NZ . LYS B 2 15 ? -66.280 -21.729 -25.251 1.00 71.04 ? 96 LYS G NZ 1 ATOM 1469 N N . ASN B 2 16 ? -69.661 -22.815 -17.223 1.00 76.92 ? 97 ASN G N 1 ATOM 1470 C CA . ASN B 2 16 ? -70.654 -22.143 -16.386 1.00 76.92 ? 97 ASN G CA 1 ATOM 1471 C C . ASN B 2 16 ? -70.158 -20.812 -15.797 1.00 76.92 ? 97 ASN G C 1 ATOM 1472 O O . ASN B 2 16 ? -69.259 -20.743 -14.975 1.00 76.92 ? 97 ASN G O 1 ATOM 1473 C CB . ASN B 2 16 ? -71.058 -23.012 -15.211 1.00 105.12 ? 97 ASN G CB 1 ATOM 1474 C CG . ASN B 2 16 ? -72.147 -22.364 -14.411 1.00 105.12 ? 97 ASN G CG 1 ATOM 1475 O OD1 . ASN B 2 16 ? -72.320 -21.153 -14.459 1.00 105.12 ? 97 ASN G OD1 1 ATOM 1476 N ND2 . ASN B 2 16 ? -72.928 -23.160 -13.720 1.00 105.12 ? 97 ASN G ND2 1 ATOM 1477 N N . ASP B 2 17 ? -70.898 -19.792 -16.204 1.00 108.93 ? 98 ASP G N 1 ATOM 1478 C CA . ASP B 2 17 ? -70.734 -18.383 -15.925 1.00 108.93 ? 98 ASP G CA 1 ATOM 1479 C C . ASP B 2 17 ? -70.811 -18.126 -14.400 1.00 108.93 ? 98 ASP G C 1 ATOM 1480 O O . ASP B 2 17 ? -70.138 -17.236 -13.886 1.00 108.93 ? 98 ASP G O 1 ATOM 1481 C CB . ASP B 2 17 ? -71.795 -17.639 -16.769 1.00 158.95 ? 98 ASP G CB 1 ATOM 1482 C CG . ASP B 2 17 ? -71.774 -16.127 -16.603 1.00 158.95 ? 98 ASP G CG 1 ATOM 1483 O OD1 . ASP B 2 17 ? -72.475 -15.470 -17.405 1.00 158.95 ? 98 ASP G OD1 1 ATOM 1484 O OD2 . ASP B 2 17 ? -71.041 -15.581 -15.754 1.00 158.95 ? 98 ASP G OD2 1 ATOM 1485 N N . MET B 2 18 ? -71.716 -18.808 -13.696 1.00 94.40 ? 99 MET G N 1 ATOM 1486 C CA . MET B 2 18 ? -71.827 -18.674 -12.221 1.00 94.40 ? 99 MET G CA 1 ATOM 1487 C C . MET B 2 18 ? -70.569 -19.058 -11.397 1.00 94.40 ? 99 MET G C 1 ATOM 1488 O O . MET B 2 18 ? -70.222 -18.371 -10.413 1.00 94.40 ? 99 MET G O 1 ATOM 1489 C CB . MET B 2 18 ? -72.931 -19.538 -11.632 1.00 123.31 ? 99 MET G CB 1 ATOM 1490 C CG . MET B 2 18 ? -74.324 -19.171 -11.906 1.00 123.31 ? 99 MET G CG 1 ATOM 1491 S SD . MET B 2 18 ? -75.281 -20.407 -11.044 1.00 123.31 ? 99 MET G SD 1 ATOM 1492 C CE . MET B 2 18 ? -74.928 -21.906 -12.017 1.00 123.31 ? 99 MET G CE 1 ATOM 1493 N N . VAL B 2 19 ? -69.875 -20.140 -11.796 1.00 109.37 ? 100 VAL G N 1 ATOM 1494 C CA . VAL B 2 19 ? -68.736 -20.620 -11.008 1.00 109.37 ? 100 VAL G CA 1 ATOM 1495 C C . VAL B 2 19 ? -67.768 -19.494 -10.984 1.00 109.37 ? 100 VAL G C 1 ATOM 1496 O O . VAL B 2 19 ? -67.098 -19.330 -10.001 1.00 109.37 ? 100 VAL G O 1 ATOM 1497 C CB . VAL B 2 19 ? -67.975 -21.902 -11.587 1.00 53.55 ? 100 VAL G CB 1 ATOM 1498 C CG1 . VAL B 2 19 ? -68.976 -23.081 -11.728 1.00 53.55 ? 100 VAL G CG1 1 ATOM 1499 C CG2 . VAL B 2 19 ? -67.176 -21.560 -12.908 1.00 53.55 ? 100 VAL G CG2 1 ATOM 1500 N N . ASP B 2 20 ? -67.593 -18.781 -12.090 1.00 79.89 ? 101 ASP G N 1 ATOM 1501 C CA . ASP B 2 20 ? -66.643 -17.712 -11.991 1.00 79.89 ? 101 ASP G CA 1 ATOM 1502 C C . ASP B 2 20 ? -67.158 -16.752 -10.900 1.00 79.89 ? 101 ASP G C 1 ATOM 1503 O O . ASP B 2 20 ? -66.354 -16.243 -10.118 1.00 79.89 ? 101 ASP G O 1 ATOM 1504 C CB . ASP B 2 20 ? -66.626 -16.860 -13.270 1.00 98.87 ? 101 ASP G CB 1 ATOM 1505 C CG . ASP B 2 20 ? -66.036 -17.578 -14.450 1.00 98.87 ? 101 ASP G CG 1 ATOM 1506 O OD1 . ASP B 2 20 ? -65.465 -18.657 -14.261 1.00 98.87 ? 101 ASP G OD1 1 ATOM 1507 O OD2 . ASP B 2 20 ? -66.081 -17.019 -15.561 1.00 98.87 ? 101 ASP G OD2 1 ATOM 1508 N N . GLN B 2 21 ? -68.473 -16.474 -10.878 1.00 83.59 ? 102 GLN G N 1 ATOM 1509 C CA . GLN B 2 21 ? -69.084 -15.661 -9.824 1.00 83.59 ? 102 GLN G CA 1 ATOM 1510 C C . GLN B 2 21 ? -68.926 -16.225 -8.438 1.00 83.59 ? 102 GLN G C 1 ATOM 1511 O O . GLN B 2 21 ? -68.592 -15.506 -7.479 1.00 83.59 ? 102 GLN G O 1 ATOM 1512 C CB . GLN B 2 21 ? -70.573 -15.410 -10.102 1.00 110.09 ? 102 GLN G CB 1 ATOM 1513 C CG . GLN B 2 21 ? -71.359 -14.551 -9.056 1.00 110.09 ? 102 GLN G CG 1 ATOM 1514 C CD . GLN B 2 21 ? -70.853 -13.120 -8.826 1.00 110.09 ? 102 GLN G CD 1 ATOM 1515 O OE1 . GLN B 2 21 ? -70.682 -12.367 -9.772 1.00 110.09 ? 102 GLN G OE1 1 ATOM 1516 N NE2 . GLN B 2 21 ? -70.654 -12.738 -7.559 1.00 110.09 ? 102 GLN G NE2 1 ATOM 1517 N N . MET B 2 22 ? -69.274 -17.519 -8.343 1.00 123.89 ? 103 MET G N 1 ATOM 1518 C CA . MET B 2 22 ? -69.228 -18.280 -7.082 1.00 123.89 ? 103 MET G CA 1 ATOM 1519 C C . MET B 2 22 ? -67.757 -18.298 -6.525 1.00 123.89 ? 103 MET G C 1 ATOM 1520 O O . MET B 2 22 ? -67.514 -18.164 -5.311 1.00 123.89 ? 103 MET G O 1 ATOM 1521 C CB . MET B 2 22 ? -69.768 -19.712 -7.337 1.00 96.87 ? 103 MET G CB 1 ATOM 1522 C CG . MET B 2 22 ? -69.816 -20.660 -6.128 1.00 96.87 ? 103 MET G CG 1 ATOM 1523 S SD . MET B 2 22 ? -71.086 -19.990 -4.827 1.00 96.87 ? 103 MET G SD 1 ATOM 1524 C CE . MET B 2 22 ? -72.540 -19.690 -5.778 1.00 96.87 ? 103 MET G CE 1 ATOM 1525 N N . HIS B 2 23 ? -66.793 -18.489 -7.449 1.00 99.58 ? 104 HIS G N 1 ATOM 1526 C CA . HIS B 2 23 ? -65.352 -18.471 -7.154 1.00 99.58 ? 104 HIS G CA 1 ATOM 1527 C C . HIS B 2 23 ? -65.015 -17.113 -6.592 1.00 99.58 ? 104 HIS G C 1 ATOM 1528 O O . HIS B 2 23 ? -64.239 -16.997 -5.680 1.00 99.58 ? 104 HIS G O 1 ATOM 1529 C CB . HIS B 2 23 ? -64.580 -18.678 -8.436 1.00 82.40 ? 104 HIS G CB 1 ATOM 1530 C CG . HIS B 2 23 ? -63.113 -18.680 -8.273 1.00 82.40 ? 104 HIS G CG 1 ATOM 1531 N ND1 . HIS B 2 23 ? -62.440 -19.694 -7.644 1.00 82.40 ? 104 HIS G ND1 1 ATOM 1532 C CD2 . HIS B 2 23 ? -62.182 -17.806 -8.685 1.00 82.40 ? 104 HIS G CD2 1 ATOM 1533 C CE1 . HIS B 2 23 ? -61.148 -19.444 -7.675 1.00 82.40 ? 104 HIS G CE1 1 ATOM 1534 N NE2 . HIS B 2 23 ? -60.965 -18.304 -8.304 1.00 82.40 ? 104 HIS G NE2 1 ATOM 1535 N N . GLN B 2 24 ? -65.560 -16.067 -7.194 1.00 63.67 ? 105 GLN G N 1 ATOM 1536 C CA . GLN B 2 24 ? -65.375 -14.759 -6.647 1.00 63.67 ? 105 GLN G CA 1 ATOM 1537 C C . GLN B 2 24 ? -65.940 -14.463 -5.310 1.00 63.67 ? 105 GLN G C 1 ATOM 1538 O O . GLN B 2 24 ? -65.234 -13.808 -4.500 1.00 63.67 ? 105 GLN G O 1 ATOM 1539 C CB . GLN B 2 24 ? -65.909 -13.725 -7.611 1.00 100.80 ? 105 GLN G CB 1 ATOM 1540 C CG . GLN B 2 24 ? -65.076 -13.652 -8.760 1.00 100.80 ? 105 GLN G CG 1 ATOM 1541 C CD . GLN B 2 24 ? -63.854 -13.039 -8.239 1.00 100.80 ? 105 GLN G CD 1 ATOM 1542 O OE1 . GLN B 2 24 ? -62.784 -13.587 -8.344 1.00 100.80 ? 105 GLN G OE1 1 ATOM 1543 N NE2 . GLN B 2 24 ? -64.008 -11.881 -7.613 1.00 100.80 ? 105 GLN G NE2 1 ATOM 1544 N N . ASP B 2 25 ? -67.159 -14.989 -5.076 1.00 123.36 ? 106 ASP G N 1 ATOM 1545 C CA . ASP B 2 25 ? -67.908 -14.841 -3.826 1.00 123.36 ? 106 ASP G CA 1 ATOM 1546 C C . ASP B 2 25 ? -67.134 -15.471 -2.682 1.00 123.36 ? 106 ASP G C 1 ATOM 1547 O O . ASP B 2 25 ? -67.183 -14.971 -1.550 1.00 123.36 ? 106 ASP G O 1 ATOM 1548 C CB . ASP B 2 25 ? -69.344 -15.356 -3.990 1.00 108.67 ? 106 ASP G CB 1 ATOM 1549 C CG . ASP B 2 25 ? -70.200 -14.429 -4.892 1.00 108.67 ? 106 ASP G CG 1 ATOM 1550 O OD1 . ASP B 2 25 ? -69.847 -13.243 -5.079 1.00 108.67 ? 106 ASP G OD1 1 ATOM 1551 O OD2 . ASP B 2 25 ? -71.218 -14.901 -5.441 1.00 108.67 ? 106 ASP G OD2 1 ATOM 1552 N N . ILE B 2 26 ? -66.520 -16.632 -2.973 1.00 80.46 ? 107 ILE G N 1 ATOM 1553 C CA . ILE B 2 26 ? -65.569 -17.349 -2.058 1.00 80.46 ? 107 ILE G CA 1 ATOM 1554 C C . ILE B 2 26 ? -64.315 -16.544 -1.688 1.00 80.46 ? 107 ILE G C 1 ATOM 1555 O O . ILE B 2 26 ? -63.925 -16.554 -0.523 1.00 80.46 ? 107 ILE G O 1 ATOM 1556 C CB . ILE B 2 26 ? -65.111 -18.693 -2.653 1.00 75.84 ? 107 ILE G CB 1 ATOM 1557 C CG1 . ILE B 2 26 ? -66.346 -19.571 -2.869 1.00 75.84 ? 107 ILE G CG1 1 ATOM 1558 C CG2 . ILE B 2 26 ? -64.017 -19.277 -1.832 1.00 75.84 ? 107 ILE G CG2 1 ATOM 1559 C CD1 . ILE B 2 26 ? -67.068 -19.818 -1.566 1.00 75.84 ? 107 ILE G CD1 1 ATOM 1560 N N . ILE B 2 27 ? -63.728 -15.857 -2.682 1.00 112.50 ? 108 ILE G N 1 ATOM 1561 C CA . ILE B 2 27 ? -62.578 -14.991 -2.476 1.00 112.50 ? 108 ILE G CA 1 ATOM 1562 C C . ILE B 2 27 ? -62.952 -13.888 -1.487 1.00 112.50 ? 108 ILE G C 1 ATOM 1563 O O . ILE B 2 27 ? -62.179 -13.573 -0.574 1.00 112.50 ? 108 ILE G O 1 ATOM 1564 C CB . ILE B 2 27 ? -62.091 -14.376 -3.805 1.00 77.27 ? 108 ILE G CB 1 ATOM 1565 C CG1 . ILE B 2 27 ? -61.625 -15.484 -4.736 1.00 77.27 ? 108 ILE G CG1 1 ATOM 1566 C CG2 . ILE B 2 27 ? -60.872 -13.431 -3.577 1.00 77.27 ? 108 ILE G CG2 1 ATOM 1567 C CD1 . ILE B 2 27 ? -60.483 -16.285 -4.107 1.00 77.27 ? 108 ILE G CD1 1 ATOM 1568 N N . SER B 2 28 ? -64.077 -13.217 -1.712 1.00 93.94 ? 109 SER G N 1 ATOM 1569 C CA . SER B 2 28 ? -64.555 -12.220 -0.732 1.00 93.94 ? 109 SER G CA 1 ATOM 1570 C C . SER B 2 28 ? -64.844 -12.769 0.670 1.00 93.94 ? 109 SER G C 1 ATOM 1571 O O . SER B 2 28 ? -64.535 -12.122 1.658 1.00 93.94 ? 109 SER G O 1 ATOM 1572 C CB . SER B 2 28 ? -65.805 -11.515 -1.255 1.00 103.82 ? 109 SER G CB 1 ATOM 1573 O OG . SER B 2 28 ? -65.444 -10.820 -2.435 1.00 103.82 ? 109 SER G OG 1 ATOM 1574 N N . LEU B 2 29 ? -65.436 -13.968 0.741 1.00 123.03 ? 110 LEU G N 1 ATOM 1575 C CA . LEU B 2 29 ? -65.825 -14.569 2.023 1.00 123.03 ? 110 LEU G CA 1 ATOM 1576 C C . LEU B 2 29 ? -64.518 -14.688 2.776 1.00 123.03 ? 110 LEU G C 1 ATOM 1577 O O . LEU B 2 29 ? -64.451 -14.445 3.986 1.00 123.03 ? 110 LEU G O 1 ATOM 1578 C CB . LEU B 2 29 ? -66.566 -15.924 1.797 1.00 119.79 ? 110 LEU G CB 1 ATOM 1579 C CG . LEU B 2 29 ? -67.118 -16.833 2.924 1.00 119.79 ? 110 LEU G CG 1 ATOM 1580 C CD1 . LEU B 2 29 ? -68.207 -16.069 3.653 1.00 119.79 ? 110 LEU G CD1 1 ATOM 1581 C CD2 . LEU B 2 29 ? -67.712 -18.114 2.380 1.00 119.79 ? 110 LEU G CD2 1 ATOM 1582 N N . TRP B 2 30 ? -63.505 -15.167 2.061 1.00 78.40 ? 111 TRP G N 1 ATOM 1583 C CA . TRP B 2 30 ? -62.146 -15.209 2.610 1.00 78.40 ? 111 TRP G CA 1 ATOM 1584 C C . TRP B 2 30 ? -61.525 -13.892 3.020 1.00 78.40 ? 111 TRP G C 1 ATOM 1585 O O . TRP B 2 30 ? -60.862 -13.826 4.036 1.00 78.40 ? 111 TRP G O 1 ATOM 1586 C CB . TRP B 2 30 ? -61.183 -16.000 1.722 1.00 124.64 ? 111 TRP G CB 1 ATOM 1587 C CG . TRP B 2 30 ? -61.265 -17.510 1.871 1.00 124.64 ? 111 TRP G CG 1 ATOM 1588 C CD1 . TRP B 2 30 ? -62.197 -18.358 1.328 1.00 124.64 ? 111 TRP G CD1 1 ATOM 1589 C CD2 . TRP B 2 30 ? -60.246 -18.351 2.416 1.00 124.64 ? 111 TRP G CD2 1 ATOM 1590 N NE1 . TRP B 2 30 ? -61.817 -19.671 1.501 1.00 124.64 ? 111 TRP G NE1 1 ATOM 1591 C CE2 . TRP B 2 30 ? -60.620 -19.694 2.160 1.00 124.64 ? 111 TRP G CE2 1 ATOM 1592 C CE3 . TRP B 2 30 ? -59.043 -18.101 3.087 1.00 124.64 ? 111 TRP G CE3 1 ATOM 1593 C CZ2 . TRP B 2 30 ? -59.832 -20.781 2.552 1.00 124.64 ? 111 TRP G CZ2 1 ATOM 1594 C CZ3 . TRP B 2 30 ? -58.259 -19.183 3.475 1.00 124.64 ? 111 TRP G CZ3 1 ATOM 1595 C CH2 . TRP B 2 30 ? -58.658 -20.507 3.206 1.00 124.64 ? 111 TRP G CH2 1 ATOM 1596 N N . ASP B 2 31 ? -61.730 -12.832 2.246 1.00 134.91 ? 112 ASP G N 1 ATOM 1597 C CA . ASP B 2 31 ? -61.128 -11.584 2.676 1.00 134.91 ? 112 ASP G CA 1 ATOM 1598 C C . ASP B 2 31 ? -61.703 -11.249 4.053 1.00 134.91 ? 112 ASP G C 1 ATOM 1599 O O . ASP B 2 31 ? -60.965 -10.845 4.950 1.00 134.91 ? 112 ASP G O 1 ATOM 1600 C CB . ASP B 2 31 ? -61.561 -10.427 1.787 1.00 80.84 ? 112 ASP G CB 1 ATOM 1601 C CG . ASP B 2 31 ? -60.952 -9.118 2.210 1.00 80.84 ? 112 ASP G CG 1 ATOM 1602 O OD1 . ASP B 2 31 ? -60.302 -9.087 3.270 1.00 80.84 ? 112 ASP G OD1 1 ATOM 1603 O OD2 . ASP B 2 31 ? -61.245 -8.076 1.590 1.00 80.84 ? 112 ASP G OD2 1 ATOM 1604 N N . GLN B 2 32 ? -63.028 -11.311 4.210 1.00 73.45 ? 113 GLN G N 1 ATOM 1605 C CA . GLN B 2 32 ? -63.589 -11.014 5.531 1.00 73.45 ? 113 GLN G CA 1 ATOM 1606 C C . GLN B 2 32 ? -63.168 -11.891 6.755 1.00 73.45 ? 113 GLN G C 1 ATOM 1607 O O . GLN B 2 32 ? -62.712 -11.368 7.792 1.00 73.45 ? 113 GLN G O 1 ATOM 1608 C CB . GLN B 2 32 ? -65.104 -11.062 5.287 1.00 119.06 ? 113 GLN G CB 1 ATOM 1609 C CG . GLN B 2 32 ? -66.058 -10.814 6.384 1.00 119.06 ? 113 GLN G CG 1 ATOM 1610 C CD . GLN B 2 32 ? -67.487 -10.928 5.848 1.00 119.06 ? 113 GLN G CD 1 ATOM 1611 O OE1 . GLN B 2 32 ? -67.849 -11.889 5.164 1.00 119.06 ? 113 GLN G OE1 1 ATOM 1612 N NE2 . GLN B 2 32 ? -68.300 -9.932 6.146 1.00 119.06 ? 113 GLN G NE2 1 ATOM 1613 N N . SER B 2 33 ? -63.265 -13.220 6.574 1.00 142.88 ? 114 SER G N 1 ATOM 1614 C CA . SER B 2 33 ? -62.844 -14.251 7.544 1.00 142.88 ? 114 SER G CA 1 ATOM 1615 C C . SER B 2 33 ? -61.430 -14.659 7.994 1.00 142.88 ? 114 SER G C 1 ATOM 1616 O O . SER B 2 33 ? -61.180 -14.843 9.188 1.00 142.88 ? 114 SER G O 1 ATOM 1617 C CB . SER B 2 33 ? -63.613 -15.549 7.264 1.00 96.66 ? 114 SER G CB 1 ATOM 1618 O OG . SER B 2 33 ? -63.251 -16.559 8.206 1.00 96.66 ? 114 SER G OG 1 ATOM 1619 N N . LEU B 2 34 ? -60.496 -14.774 7.042 1.00 104.54 ? 115 LEU G N 1 ATOM 1620 C CA . LEU B 2 34 ? -59.158 -15.204 7.425 1.00 104.54 ? 115 LEU G CA 1 ATOM 1621 C C . LEU B 2 34 ? -58.314 -14.121 6.746 1.00 104.54 ? 115 LEU G C 1 ATOM 1622 O O . LEU B 2 34 ? -57.949 -14.278 5.618 1.00 104.54 ? 115 LEU G O 1 ATOM 1623 C CB . LEU B 2 34 ? -58.899 -16.557 6.739 1.00 74.08 ? 115 LEU G CB 1 ATOM 1624 C CG . LEU B 2 34 ? -59.917 -17.673 7.071 1.00 74.08 ? 115 LEU G CG 1 ATOM 1625 C CD1 . LEU B 2 34 ? -59.475 -18.906 6.296 1.00 74.08 ? 115 LEU G CD1 1 ATOM 1626 C CD2 . LEU B 2 34 ? -60.210 -17.895 8.553 1.00 74.08 ? 115 LEU G CD2 1 ATOM 1627 N N . LYS B 2 35 ? -57.854 -13.117 7.454 1.00 96.39 ? 116 LYS G N 1 ATOM 1628 C CA . LYS B 2 35 ? -57.139 -12.080 6.766 1.00 96.39 ? 116 LYS G CA 1 ATOM 1629 C C . LYS B 2 35 ? -55.682 -12.301 7.033 1.00 96.39 ? 116 LYS G C 1 ATOM 1630 O O . LYS B 2 35 ? -55.239 -12.248 8.171 1.00 96.39 ? 116 LYS G O 1 ATOM 1631 C CB . LYS B 2 35 ? -57.593 -10.698 7.274 1.00 132.09 ? 116 LYS G CB 1 ATOM 1632 C CG . LYS B 2 35 ? -59.106 -10.448 7.286 1.00 132.09 ? 116 LYS G CG 1 ATOM 1633 C CD . LYS B 2 35 ? -59.466 -8.974 7.132 1.00 132.09 ? 116 LYS G CD 1 ATOM 1634 C CE . LYS B 2 35 ? -58.679 -8.063 8.060 1.00 132.09 ? 116 LYS G CE 1 ATOM 1635 N NZ . LYS B 2 35 ? -57.609 -7.321 7.333 1.00 132.09 ? 116 LYS G NZ 1 ATOM 1636 N N . PRO B 2 36 ? -54.901 -12.543 6.011 1.00 80.06 ? 117 PRO G N 1 ATOM 1637 C CA . PRO B 2 36 ? -53.522 -12.735 6.414 1.00 80.06 ? 117 PRO G CA 1 ATOM 1638 C C . PRO B 2 36 ? -52.939 -11.441 6.968 1.00 80.06 ? 117 PRO G C 1 ATOM 1639 O O . PRO B 2 36 ? -53.448 -10.341 6.648 1.00 80.06 ? 117 PRO G O 1 ATOM 1640 C CB . PRO B 2 36 ? -52.854 -13.227 5.141 1.00 103.28 ? 117 PRO G CB 1 ATOM 1641 C CG . PRO B 2 36 ? -53.729 -12.700 4.080 1.00 103.28 ? 117 PRO G CG 1 ATOM 1642 C CD . PRO B 2 36 ? -55.100 -12.870 4.607 1.00 103.28 ? 117 PRO G CD 1 ATOM 1643 N N . CYS B 2 37 ? -51.962 -11.607 7.887 1.00 86.14 ? 118 CYS G N 1 ATOM 1644 C CA . CYS B 2 37 ? -51.254 -10.518 8.569 1.00 86.14 ? 118 CYS G CA 1 ATOM 1645 C C . CYS B 2 37 ? -50.416 -9.912 7.442 1.00 86.14 ? 118 CYS G C 1 ATOM 1646 O O . CYS B 2 37 ? -50.217 -8.713 7.318 1.00 86.14 ? 118 CYS G O 1 ATOM 1647 C CB . CYS B 2 37 ? -50.351 -11.137 9.622 1.00 156.75 ? 118 CYS G CB 1 ATOM 1648 S SG . CYS B 2 37 ? -51.267 -12.203 10.806 1.00 156.75 ? 118 CYS G SG 1 ATOM 1649 N N . VAL B 2 38 ? -49.896 -10.811 6.639 1.00 67.60 ? 119 VAL G N 1 ATOM 1650 C CA . VAL B 2 38 ? -49.122 -10.438 5.501 1.00 67.60 ? 119 VAL G CA 1 ATOM 1651 C C . VAL B 2 38 ? -49.513 -10.975 4.114 1.00 67.60 ? 119 VAL G C 1 ATOM 1652 O O . VAL B 2 38 ? -49.675 -12.178 3.918 1.00 67.60 ? 119 VAL G O 1 ATOM 1653 C CB . VAL B 2 38 ? -47.649 -10.839 5.727 1.00 68.12 ? 119 VAL G CB 1 ATOM 1654 C CG1 . VAL B 2 38 ? -46.825 -10.442 4.515 1.00 68.12 ? 119 VAL G CG1 1 ATOM 1655 C CG2 . VAL B 2 38 ? -47.074 -10.106 6.960 1.00 68.12 ? 119 VAL G CG2 1 ATOM 1656 N N . LYS B 2 39 ? -49.619 -10.085 3.133 1.00 66.80 ? 120 LYS G N 1 ATOM 1657 C CA . LYS B 2 39 ? -49.771 -10.554 1.763 1.00 66.80 ? 120 LYS G CA 1 ATOM 1658 C C . LYS B 2 39 ? -48.548 -9.950 1.104 1.00 66.80 ? 120 LYS G C 1 ATOM 1659 O O . LYS B 2 39 ? -48.195 -8.786 1.328 1.00 66.80 ? 120 LYS G O 1 ATOM 1660 C CB . LYS B 2 39 ? -50.988 -9.995 0.994 1.00 97.37 ? 120 LYS G CB 1 ATOM 1661 C CG . LYS B 2 39 ? -52.364 -10.442 1.398 1.00 97.37 ? 120 LYS G CG 1 ATOM 1662 C CD . LYS B 2 39 ? -53.381 -9.773 0.516 1.00 97.37 ? 120 LYS G CD 1 ATOM 1663 C CE . LYS B 2 39 ? -54.782 -10.188 0.880 1.00 97.37 ? 120 LYS G CE 1 ATOM 1664 N NZ . LYS B 2 39 ? -55.004 -11.608 0.512 1.00 97.37 ? 120 LYS G NZ 1 ATOM 1665 N N . LEU B 2 40 ? -47.904 -10.757 0.280 1.00 78.77 ? 121 LEU G N 1 ATOM 1666 C CA . LEU B 2 40 ? -46.782 -10.276 -0.462 1.00 78.77 ? 121 LEU G CA 1 ATOM 1667 C C . LEU B 2 40 ? -47.334 -10.521 -1.852 1.00 78.77 ? 121 LEU G C 1 ATOM 1668 O O . LEU B 2 40 ? -47.881 -11.583 -2.170 1.00 78.77 ? 121 LEU G O 1 ATOM 1669 C CB . LEU B 2 40 ? -45.547 -11.108 -0.074 1.00 74.13 ? 121 LEU G CB 1 ATOM 1670 C CG . LEU B 2 40 ? -45.253 -10.761 1.412 1.00 74.13 ? 121 LEU G CG 1 ATOM 1671 C CD1 . LEU B 2 40 ? -44.229 -11.638 2.061 1.00 74.13 ? 121 LEU G CD1 1 ATOM 1672 C CD2 . LEU B 2 40 ? -44.783 -9.331 1.496 1.00 74.13 ? 121 LEU G CD2 1 ATOM 1673 N N . THR B 2 41 ? -47.246 -9.489 -2.658 1.00 109.89 ? 122 THR G N 1 ATOM 1674 C CA . THR B 2 41 ? -47.693 -9.538 -4.027 1.00 109.89 ? 122 THR G CA 1 ATOM 1675 C C . THR B 2 41 ? -46.872 -8.809 -5.056 1.00 109.89 ? 122 THR G C 1 ATOM 1676 O O . THR B 2 41 ? -46.077 -7.921 -4.758 1.00 109.89 ? 122 THR G O 1 ATOM 1677 C CB . THR B 2 41 ? -49.140 -9.129 -4.090 1.00 55.10 ? 122 THR G CB 1 ATOM 1678 O OG1 . THR B 2 41 ? -49.258 -7.790 -3.578 1.00 55.10 ? 122 THR G OG1 1 ATOM 1679 C CG2 . THR B 2 41 ? -50.006 -10.105 -3.374 1.00 55.10 ? 122 THR G CG2 1 ATOM 1680 N N . PRO B 2 42 ? -47.044 -9.187 -6.300 1.00 63.26 ? 123 PRO G N 1 ATOM 1681 C CA . PRO B 2 42 ? -46.224 -8.425 -7.232 1.00 63.26 ? 123 PRO G CA 1 ATOM 1682 C C . PRO B 2 42 ? -47.062 -7.197 -7.744 1.00 63.26 ? 123 PRO G C 1 ATOM 1683 O O . PRO B 2 42 ? -47.703 -6.435 -6.943 1.00 63.26 ? 123 PRO G O 1 ATOM 1684 C CB . PRO B 2 42 ? -45.875 -9.470 -8.289 1.00 37.66 ? 123 PRO G CB 1 ATOM 1685 C CG . PRO B 2 42 ? -46.981 -10.422 -8.240 1.00 37.66 ? 123 PRO G CG 1 ATOM 1686 C CD . PRO B 2 42 ? -47.364 -10.530 -6.800 1.00 37.66 ? 123 PRO G CD 1 ATOM 1687 N N . ASN B 2 51 ? -42.348 -3.415 -8.333 1.00 147.59 ? 193 ASN G N 1 ATOM 1688 C CA . ASN B 2 51 ? -42.402 -3.261 -6.870 1.00 147.59 ? 193 ASN G CA 1 ATOM 1689 C C . ASN B 2 51 ? -43.171 -4.471 -6.316 1.00 147.59 ? 193 ASN G C 1 ATOM 1690 O O . ASN B 2 51 ? -43.590 -5.358 -7.069 1.00 147.59 ? 193 ASN G O 1 ATOM 1691 C CB . ASN B 2 51 ? -43.144 -1.951 -6.473 1.00 105.40 ? 193 ASN G CB 1 ATOM 1692 C CG . ASN B 2 51 ? -43.022 -1.608 -4.970 1.00 105.40 ? 193 ASN G CG 1 ATOM 1693 O OD1 . ASN B 2 51 ? -41.913 -1.426 -4.464 1.00 105.40 ? 193 ASN G OD1 1 ATOM 1694 N ND2 . ASN B 2 51 ? -44.159 -1.487 -4.271 1.00 105.40 ? 193 ASN G ND2 1 ATOM 1695 N N . THR B 2 52 ? -43.279 -4.529 -4.994 1.00 146.76 ? 194 THR G N 1 ATOM 1696 C CA . THR B 2 52 ? -44.036 -5.555 -4.299 1.00 146.76 ? 194 THR G CA 1 ATOM 1697 C C . THR B 2 52 ? -45.074 -4.745 -3.544 1.00 146.76 ? 194 THR G C 1 ATOM 1698 O O . THR B 2 52 ? -44.700 -3.772 -2.877 1.00 146.76 ? 194 THR G O 1 ATOM 1699 C CB . THR B 2 52 ? -43.166 -6.356 -3.293 1.00 75.04 ? 194 THR G CB 1 ATOM 1700 O OG1 . THR B 2 52 ? -42.090 -7.006 -3.969 1.00 75.04 ? 194 THR G OG1 1 ATOM 1701 C CG2 . THR B 2 52 ? -44.005 -7.379 -2.563 1.00 75.04 ? 194 THR G CG2 1 ATOM 1702 N N . SER B 2 53 ? -46.364 -5.090 -3.630 1.00 103.96 ? 195 SER G N 1 ATOM 1703 C CA . SER B 2 53 ? -47.274 -4.262 -2.867 1.00 103.96 ? 195 SER G CA 1 ATOM 1704 C C . SER B 2 53 ? -47.536 -5.096 -1.602 1.00 103.96 ? 195 SER G C 1 ATOM 1705 O O . SER B 2 53 ? -48.136 -6.190 -1.650 1.00 103.96 ? 195 SER G O 1 ATOM 1706 C CB . SER B 2 53 ? -48.562 -4.098 -3.704 1.00 91.01 ? 195 SER G CB 1 ATOM 1707 O OG . SER B 2 53 ? -49.537 -3.301 -3.052 1.00 91.01 ? 195 SER G OG 1 ATOM 1708 N N . THR B 2 54 ? -47.148 -4.505 -0.462 1.00 115.47 ? 196 THR G N 1 ATOM 1709 C CA . THR B 2 54 ? -47.294 -5.134 0.845 1.00 115.47 ? 196 THR G CA 1 ATOM 1710 C C . THR B 2 54 ? -47.819 -4.328 2.043 1.00 115.47 ? 196 THR G C 1 ATOM 1711 O O . THR B 2 54 ? -47.454 -3.162 2.189 1.00 115.47 ? 196 THR G O 1 ATOM 1712 C CB . THR B 2 54 ? -45.974 -5.806 1.236 1.00 102.34 ? 196 THR G CB 1 ATOM 1713 O OG1 . THR B 2 54 ? -45.649 -6.793 0.253 1.00 102.34 ? 196 THR G OG1 1 ATOM 1714 C CG2 . THR B 2 54 ? -46.112 -6.511 2.564 1.00 102.34 ? 196 THR G CG2 1 ATOM 1715 N N . ILE B 2 55 ? -48.692 -4.923 2.864 1.00 122.14 ? 197 ILE G N 1 ATOM 1716 C CA . ILE B 2 55 ? -49.150 -4.304 4.111 1.00 122.14 ? 197 ILE G CA 1 ATOM 1717 C C . ILE B 2 55 ? -49.046 -5.226 5.326 1.00 122.14 ? 197 ILE G C 1 ATOM 1718 O O . ILE B 2 55 ? -49.445 -6.393 5.249 1.00 122.14 ? 197 ILE G O 1 ATOM 1719 C CB . ILE B 2 55 ? -50.598 -3.746 4.044 1.00 123.05 ? 197 ILE G CB 1 ATOM 1720 C CG1 . ILE B 2 55 ? -50.868 -2.910 5.308 1.00 123.05 ? 197 ILE G CG1 1 ATOM 1721 C CG2 . ILE B 2 55 ? -51.623 -4.893 3.958 1.00 123.05 ? 197 ILE G CG2 1 ATOM 1722 C CD1 . ILE B 2 55 ? -50.092 -1.589 5.362 1.00 123.05 ? 197 ILE G CD1 1 ATOM 1723 N N . ALA B 2 56 ? -48.482 -4.726 6.421 1.00 229.96 ? 198 ALA G N 1 ATOM 1724 C CA . ALA B 2 56 ? -48.408 -5.478 7.679 1.00 229.96 ? 198 ALA G CA 1 ATOM 1725 C C . ALA B 2 56 ? -49.563 -4.933 8.571 1.00 229.96 ? 198 ALA G C 1 ATOM 1726 O O . ALA B 2 56 ? -49.664 -3.728 8.766 1.00 229.96 ? 198 ALA G O 1 ATOM 1727 C CB . ALA B 2 56 ? -47.029 -5.256 8.338 1.00 72.00 ? 198 ALA G CB 1 ATOM 1728 N N . GLN B 2 57 ? -50.441 -5.803 9.081 1.00 155.80 ? 199 GLN G N 1 ATOM 1729 C CA . GLN B 2 57 ? -51.603 -5.400 9.915 1.00 155.80 ? 199 GLN G CA 1 ATOM 1730 C C . GLN B 2 57 ? -51.761 -6.365 11.107 1.00 155.80 ? 199 GLN G C 1 ATOM 1731 O O . GLN B 2 57 ? -51.192 -7.449 11.081 1.00 155.80 ? 199 GLN G O 1 ATOM 1732 C CB . GLN B 2 57 ? -52.873 -5.420 9.026 1.00 103.66 ? 199 GLN G CB 1 ATOM 1733 C CG . GLN B 2 57 ? -52.918 -4.298 7.961 1.00 103.66 ? 199 GLN G CG 1 ATOM 1734 C CD . GLN B 2 57 ? -54.026 -4.454 6.945 1.00 103.66 ? 199 GLN G CD 1 ATOM 1735 O OE1 . GLN B 2 57 ? -54.429 -5.570 6.619 1.00 103.66 ? 199 GLN G OE1 1 ATOM 1736 N NE2 . GLN B 2 57 ? -54.532 -3.329 6.448 1.00 103.66 ? 199 GLN G NE2 1 ATOM 1737 N N . ALA B 2 58 ? -52.457 -5.993 12.183 1.00 218.05 ? 200 ALA G N 1 ATOM 1738 C CA . ALA B 2 58 ? -52.629 -7.005 13.233 1.00 218.05 ? 200 ALA G CA 1 ATOM 1739 C C . ALA B 2 58 ? -53.809 -7.856 12.732 1.00 218.05 ? 200 ALA G C 1 ATOM 1740 O O . ALA B 2 58 ? -54.841 -7.311 12.329 1.00 218.05 ? 200 ALA G O 1 ATOM 1741 C CB . ALA B 2 58 ? -52.943 -6.356 14.657 1.00 17.43 ? 200 ALA G CB 1 ATOM 1742 N N . CYS B 2 59 ? -53.640 -9.180 12.716 1.00 177.53 ? 201 CYS G N 1 ATOM 1743 C CA . CYS B 2 59 ? -54.706 -10.102 12.285 1.00 177.53 ? 201 CYS G CA 1 ATOM 1744 C C . CYS B 2 59 ? -55.951 -10.290 13.164 1.00 177.53 ? 201 CYS G C 1 ATOM 1745 O O . CYS B 2 59 ? -55.870 -10.219 14.388 1.00 177.53 ? 201 CYS G O 1 ATOM 1746 C CB . CYS B 2 59 ? -54.158 -11.508 11.985 1.00 166.58 ? 201 CYS G CB 1 ATOM 1747 S SG . CYS B 2 59 ? -53.268 -11.995 10.454 1.00 166.58 ? 201 CYS G SG 1 ATOM 1748 N N . PRO B 2 60 ? -57.113 -10.592 12.540 1.00 243.96 ? 202 PRO G N 1 ATOM 1749 C CA . PRO B 2 60 ? -58.395 -10.810 13.233 1.00 243.96 ? 202 PRO G CA 1 ATOM 1750 C C . PRO B 2 60 ? -58.451 -12.165 13.941 1.00 243.96 ? 202 PRO G C 1 ATOM 1751 O O . PRO B 2 60 ? -59.187 -12.330 14.922 1.00 243.96 ? 202 PRO G O 1 ATOM 1752 C CB . PRO B 2 60 ? -59.432 -10.678 12.115 1.00 152.93 ? 202 PRO G CB 1 ATOM 1753 C CG . PRO B 2 60 ? -58.692 -11.179 10.925 1.00 152.93 ? 202 PRO G CG 1 ATOM 1754 C CD . PRO B 2 60 ? -57.308 -10.561 11.079 1.00 152.93 ? 202 PRO G CD 1 ATOM 1755 N N . LYS B 2 61 ? -57.725 -13.147 13.400 1.00 146.26 ? 203 LYS G N 1 ATOM 1756 C CA . LYS B 2 61 ? -57.636 -14.455 14.040 1.00 146.26 ? 203 LYS G CA 1 ATOM 1757 C C . LYS B 2 61 ? -59.017 -15.082 14.166 1.00 146.26 ? 203 LYS G C 1 ATOM 1758 O O . LYS B 2 61 ? -59.341 -15.679 15.198 1.00 146.26 ? 203 LYS G O 1 ATOM 1759 C CB . LYS B 2 61 ? -57.003 -14.297 15.426 1.00 101.80 ? 203 LYS G CB 1 ATOM 1760 C CG . LYS B 2 61 ? -55.571 -13.805 15.357 1.00 101.80 ? 203 LYS G CG 1 ATOM 1761 C CD . LYS B 2 61 ? -54.971 -13.659 16.754 1.00 101.80 ? 203 LYS G CD 1 ATOM 1762 C CE . LYS B 2 61 ? -53.523 -13.153 16.674 1.00 101.80 ? 203 LYS G CE 1 ATOM 1763 N NZ . LYS B 2 61 ? -53.391 -11.745 16.168 1.00 101.80 ? 203 LYS G NZ 1 ATOM 1764 N N . VAL B 2 62 ? -59.846 -14.932 13.141 1.00 211.51 ? 204 VAL G N 1 ATOM 1765 C CA . VAL B 2 62 ? -61.200 -15.457 13.249 1.00 211.51 ? 204 VAL G CA 1 ATOM 1766 C C . VAL B 2 62 ? -61.155 -16.632 12.263 1.00 211.51 ? 204 VAL G C 1 ATOM 1767 O O . VAL B 2 62 ? -60.770 -16.454 11.107 1.00 211.51 ? 204 VAL G O 1 ATOM 1768 C CB . VAL B 2 62 ? -62.271 -14.364 12.807 1.00 86.57 ? 204 VAL G CB 1 ATOM 1769 C CG1 . VAL B 2 62 ? -63.719 -14.920 12.920 1.00 86.57 ? 204 VAL G CG1 1 ATOM 1770 C CG2 . VAL B 2 62 ? -62.089 -13.074 13.613 1.00 86.57 ? 204 VAL G CG2 1 ATOM 1771 N N . SER B 2 63 ? -61.453 -17.842 12.758 1.00 176.06 ? 205 SER G N 1 ATOM 1772 C CA . SER B 2 63 ? -61.435 -19.060 11.927 1.00 176.06 ? 205 SER G CA 1 ATOM 1773 C C . SER B 2 63 ? -62.635 -19.055 11.020 1.00 176.06 ? 205 SER G C 1 ATOM 1774 O O . SER B 2 63 ? -63.634 -18.363 11.279 1.00 176.06 ? 205 SER G O 1 ATOM 1775 C CB . SER B 2 63 ? -61.571 -20.364 12.726 1.00 96.94 ? 205 SER G CB 1 ATOM 1776 O OG . SER B 2 63 ? -62.872 -20.513 13.252 1.00 96.94 ? 205 SER G OG 1 ATOM 1777 N N . PHE B 2 64 ? -62.560 -19.834 9.953 1.00 131.37 ? 206 PHE G N 1 ATOM 1778 C CA . PHE B 2 64 ? -63.729 -19.886 9.135 1.00 131.37 ? 206 PHE G CA 1 ATOM 1779 C C . PHE B 2 64 ? -64.098 -21.357 9.375 1.00 131.37 ? 206 PHE G C 1 ATOM 1780 O O . PHE B 2 64 ? -63.253 -22.259 9.304 1.00 131.37 ? 206 PHE G O 1 ATOM 1781 C CB . PHE B 2 64 ? -63.462 -19.545 7.656 1.00 139.40 ? 206 PHE G CB 1 ATOM 1782 C CG . PHE B 2 64 ? -64.718 -19.541 6.819 1.00 139.40 ? 206 PHE G CG 1 ATOM 1783 C CD1 . PHE B 2 64 ? -65.423 -18.337 6.704 1.00 139.40 ? 206 PHE G CD1 1 ATOM 1784 C CD2 . PHE B 2 64 ? -65.236 -20.675 6.213 1.00 139.40 ? 206 PHE G CD2 1 ATOM 1785 C CE1 . PHE B 2 64 ? -66.626 -18.253 6.018 1.00 139.40 ? 206 PHE G CE1 1 ATOM 1786 C CE2 . PHE B 2 64 ? -66.465 -20.594 5.508 1.00 139.40 ? 206 PHE G CE2 1 ATOM 1787 C CZ . PHE B 2 64 ? -67.156 -19.380 5.418 1.00 139.40 ? 206 PHE G CZ 1 ATOM 1788 N N . ASP B 2 65 ? -65.379 -21.568 9.642 1.00 175.71 ? 207 ASP G N 1 ATOM 1789 C CA . ASP B 2 65 ? -65.991 -22.861 9.955 1.00 175.71 ? 207 ASP G CA 1 ATOM 1790 C C . ASP B 2 65 ? -67.176 -22.877 8.998 1.00 175.71 ? 207 ASP G C 1 ATOM 1791 O O . ASP B 2 65 ? -68.300 -22.533 9.349 1.00 175.71 ? 207 ASP G O 1 ATOM 1792 C CB . ASP B 2 65 ? -66.476 -22.956 11.417 1.00 156.57 ? 207 ASP G CB 1 ATOM 1793 C CG . ASP B 2 65 ? -65.331 -23.014 12.440 1.00 156.57 ? 207 ASP G CG 1 ATOM 1794 O OD1 . ASP B 2 65 ? -64.298 -22.307 12.285 1.00 156.57 ? 207 ASP G OD1 1 ATOM 1795 O OD2 . ASP B 2 65 ? -65.489 -23.790 13.419 1.00 156.57 ? 207 ASP G OD2 1 ATOM 1796 N N . PRO B 2 66 ? -66.879 -23.219 7.730 1.00 142.16 ? 208 PRO G N 1 ATOM 1797 C CA . PRO B 2 66 ? -67.608 -23.365 6.467 1.00 142.16 ? 208 PRO G CA 1 ATOM 1798 C C . PRO B 2 66 ? -69.075 -23.056 6.412 1.00 142.16 ? 208 PRO G C 1 ATOM 1799 O O . PRO B 2 66 ? -69.877 -23.970 6.280 1.00 142.16 ? 208 PRO G O 1 ATOM 1800 C CB . PRO B 2 66 ? -67.307 -24.807 6.034 1.00 125.94 ? 208 PRO G CB 1 ATOM 1801 C CG . PRO B 2 66 ? -66.760 -25.451 7.261 1.00 125.94 ? 208 PRO G CG 1 ATOM 1802 C CD . PRO B 2 66 ? -65.933 -24.341 7.824 1.00 125.94 ? 208 PRO G CD 1 ATOM 1803 N N . ILE B 2 67 ? -69.427 -21.776 6.538 1.00 159.45 ? 209 ILE G N 1 ATOM 1804 C CA . ILE B 2 67 ? -70.826 -21.358 6.440 1.00 159.45 ? 209 ILE G CA 1 ATOM 1805 C C . ILE B 2 67 ? -71.241 -21.536 4.958 1.00 159.45 ? 209 ILE G C 1 ATOM 1806 O O . ILE B 2 67 ? -70.507 -21.088 4.067 1.00 159.45 ? 209 ILE G O 1 ATOM 1807 C CB . ILE B 2 67 ? -71.013 -19.857 6.907 1.00 136.38 ? 209 ILE G CB 1 ATOM 1808 C CG1 . ILE B 2 67 ? -70.750 -19.726 8.427 1.00 136.38 ? 209 ILE G CG1 1 ATOM 1809 C CG2 . ILE B 2 67 ? -72.445 -19.378 6.604 1.00 136.38 ? 209 ILE G CG2 1 ATOM 1810 C CD1 . ILE B 2 67 ? -71.146 -18.376 9.045 1.00 136.38 ? 209 ILE G CD1 1 ATOM 1811 N N . PRO B 2 68 ? -72.394 -22.213 4.679 1.00 162.88 ? 210 PRO G N 1 ATOM 1812 C CA . PRO B 2 68 ? -72.889 -22.439 3.303 1.00 162.88 ? 210 PRO G CA 1 ATOM 1813 C C . PRO B 2 68 ? -73.440 -21.198 2.601 1.00 162.88 ? 210 PRO G C 1 ATOM 1814 O O . PRO B 2 68 ? -73.966 -20.298 3.258 1.00 162.88 ? 210 PRO G O 1 ATOM 1815 C CB . PRO B 2 68 ? -73.938 -23.528 3.481 1.00 98.70 ? 210 PRO G CB 1 ATOM 1816 C CG . PRO B 2 68 ? -74.377 -23.370 4.923 1.00 98.70 ? 210 PRO G CG 1 ATOM 1817 C CD . PRO B 2 68 ? -73.112 -23.079 5.640 1.00 98.70 ? 210 PRO G CD 1 ATOM 1818 N N . ILE B 2 69 ? -73.351 -21.156 1.270 1.00 131.75 ? 211 ILE G N 1 ATOM 1819 C CA . ILE B 2 69 ? -73.785 -19.953 0.546 1.00 131.75 ? 211 ILE G CA 1 ATOM 1820 C C . ILE B 2 69 ? -74.751 -20.276 -0.631 1.00 131.75 ? 211 ILE G C 1 ATOM 1821 O O . ILE B 2 69 ? -74.568 -21.281 -1.317 1.00 131.75 ? 211 ILE G O 1 ATOM 1822 C CB . ILE B 2 69 ? -72.540 -19.195 -0.022 1.00 95.51 ? 211 ILE G CB 1 ATOM 1823 C CG1 . ILE B 2 69 ? -72.955 -17.820 -0.559 1.00 95.51 ? 211 ILE G CG1 1 ATOM 1824 C CG2 . ILE B 2 69 ? -71.989 -19.955 -1.261 1.00 95.51 ? 211 ILE G CG2 1 ATOM 1825 C CD1 . ILE B 2 69 ? -73.349 -16.863 0.573 1.00 95.51 ? 211 ILE G CD1 1 ATOM 1826 N N . HIS B 2 70 ? -75.798 -19.468 -0.833 1.00 110.74 ? 212 HIS G N 1 ATOM 1827 C CA . HIS B 2 70 ? -76.734 -19.715 -1.942 1.00 110.74 ? 212 HIS G CA 1 ATOM 1828 C C . HIS B 2 70 ? -76.614 -18.667 -3.032 1.00 110.74 ? 212 HIS G C 1 ATOM 1829 O O . HIS B 2 70 ? -76.977 -17.517 -2.792 1.00 110.74 ? 212 HIS G O 1 ATOM 1830 C CB . HIS B 2 70 ? -78.157 -19.579 -1.436 1.00 110.29 ? 212 HIS G CB 1 ATOM 1831 C CG . HIS B 2 70 ? -78.495 -20.532 -0.346 1.00 110.29 ? 212 HIS G CG 1 ATOM 1832 N ND1 . HIS B 2 70 ? -78.816 -21.847 -0.578 1.00 110.29 ? 212 HIS G ND1 1 ATOM 1833 C CD2 . HIS B 2 70 ? -78.561 -20.359 0.994 1.00 110.29 ? 212 HIS G CD2 1 ATOM 1834 C CE1 . HIS B 2 70 ? -79.074 -22.445 0.574 1.00 110.29 ? 212 HIS G CE1 1 ATOM 1835 N NE2 . HIS B 2 70 ? -78.927 -21.563 1.544 1.00 110.29 ? 212 HIS G NE2 1 ATOM 1836 N N . TYR B 2 71 ? -76.251 -19.051 -4.254 1.00 177.18 ? 213 TYR G N 1 ATOM 1837 C CA . TYR B 2 71 ? -76.277 -18.033 -5.291 1.00 177.18 ? 213 TYR G CA 1 ATOM 1838 C C . TYR B 2 71 ? -77.603 -18.492 -5.841 1.00 177.18 ? 213 TYR G C 1 ATOM 1839 O O . TYR B 2 71 ? -77.774 -19.607 -6.329 1.00 177.18 ? 213 TYR G O 1 ATOM 1840 C CB . TYR B 2 71 ? -75.090 -18.154 -6.327 1.00 102.72 ? 213 TYR G CB 1 ATOM 1841 C CG . TYR B 2 71 ? -75.151 -17.155 -7.527 1.00 102.72 ? 213 TYR G CG 1 ATOM 1842 C CD1 . TYR B 2 71 ? -74.562 -15.873 -7.510 1.00 102.72 ? 213 TYR G CD1 1 ATOM 1843 C CD2 . TYR B 2 71 ? -75.876 -17.520 -8.704 1.00 102.72 ? 213 TYR G CD2 1 ATOM 1844 C CE1 . TYR B 2 71 ? -74.734 -14.981 -8.651 1.00 102.72 ? 213 TYR G CE1 1 ATOM 1845 C CE2 . TYR B 2 71 ? -76.033 -16.647 -9.820 1.00 102.72 ? 213 TYR G CE2 1 ATOM 1846 C CZ . TYR B 2 71 ? -75.479 -15.396 -9.781 1.00 102.72 ? 213 TYR G CZ 1 ATOM 1847 O OH . TYR B 2 71 ? -75.763 -14.578 -10.835 1.00 102.72 ? 213 TYR G OH 1 ATOM 1848 N N . CYS B 2 72 ? -78.529 -17.559 -5.795 1.00 149.18 ? 214 CYS G N 1 ATOM 1849 C CA . CYS B 2 72 ? -79.875 -17.750 -6.249 1.00 149.18 ? 214 CYS G CA 1 ATOM 1850 C C . CYS B 2 72 ? -79.974 -16.911 -7.479 1.00 149.18 ? 214 CYS G C 1 ATOM 1851 O O . CYS B 2 72 ? -79.224 -15.956 -7.646 1.00 149.18 ? 214 CYS G O 1 ATOM 1852 C CB . CYS B 2 72 ? -80.880 -17.296 -5.187 1.00 196.79 ? 214 CYS G CB 1 ATOM 1853 S SG . CYS B 2 72 ? -82.459 -18.205 -5.235 1.00 196.79 ? 214 CYS G SG 1 ATOM 1854 N N . ALA B 2 73 ? -80.888 -17.258 -8.353 1.00 162.33 ? 215 ALA G N 1 ATOM 1855 C CA . ALA B 2 73 ? -81.021 -16.491 -9.559 1.00 162.33 ? 215 ALA G CA 1 ATOM 1856 C C . ALA B 2 73 ? -81.597 -15.103 -9.249 1.00 162.33 ? 215 ALA G C 1 ATOM 1857 O O . ALA B 2 73 ? -82.592 -14.986 -8.530 1.00 162.33 ? 215 ALA G O 1 ATOM 1858 C CB . ALA B 2 73 ? -81.915 -17.219 -10.467 1.00 105.36 ? 215 ALA G CB 1 ATOM 1859 N N . PRO B 2 74 ? -80.943 -14.030 -9.761 1.00 213.40 ? 216 PRO G N 1 ATOM 1860 C CA . PRO B 2 74 ? -81.286 -12.603 -9.615 1.00 213.40 ? 216 PRO G CA 1 ATOM 1861 C C . PRO B 2 74 ? -82.701 -12.244 -10.068 1.00 213.40 ? 216 PRO G C 1 ATOM 1862 O O . PRO B 2 74 ? -83.626 -13.026 -9.878 1.00 213.40 ? 216 PRO G O 1 ATOM 1863 C CB . PRO B 2 74 ? -80.212 -11.911 -10.440 1.00 119.47 ? 216 PRO G CB 1 ATOM 1864 C CG . PRO B 2 74 ? -79.014 -12.807 -10.201 1.00 119.47 ? 216 PRO G CG 1 ATOM 1865 C CD . PRO B 2 74 ? -79.617 -14.176 -10.391 1.00 119.47 ? 216 PRO G CD 1 ATOM 1866 N N . ALA B 2 75 ? -82.883 -11.115 -10.736 1.00 108.88 ? 217 ALA G N 1 ATOM 1867 C CA . ALA B 2 75 ? -84.250 -10.773 -11.110 1.00 108.88 ? 217 ALA G CA 1 ATOM 1868 C C . ALA B 2 75 ? -84.514 -11.129 -12.548 1.00 108.88 ? 217 ALA G C 1 ATOM 1869 O O . ALA B 2 75 ? -83.881 -10.573 -13.437 1.00 108.88 ? 217 ALA G O 1 ATOM 1870 C CB . ALA B 2 75 ? -84.480 -9.282 -10.914 1.00 68.23 ? 217 ALA G CB 1 ATOM 1871 N N . GLY B 2 76 ? -85.496 -12.010 -12.766 1.00 174.38 ? 218 GLY G N 1 ATOM 1872 C CA . GLY B 2 76 ? -85.822 -12.441 -14.117 1.00 174.38 ? 218 GLY G CA 1 ATOM 1873 C C . GLY B 2 76 ? -84.929 -13.516 -14.743 1.00 174.38 ? 218 GLY G C 1 ATOM 1874 O O . GLY B 2 76 ? -85.051 -13.810 -15.948 1.00 174.38 ? 218 GLY G O 1 ATOM 1875 N N . TYR B 2 77 ? -84.060 -14.136 -13.943 1.00 151.54 ? 219 TYR G N 1 ATOM 1876 C CA . TYR B 2 77 ? -83.118 -15.116 -14.480 1.00 151.54 ? 219 TYR G CA 1 ATOM 1877 C C . TYR B 2 77 ? -83.428 -16.418 -13.755 1.00 151.54 ? 219 TYR G C 1 ATOM 1878 O O . TYR B 2 77 ? -83.752 -16.409 -12.580 1.00 151.54 ? 219 TYR G O 1 ATOM 1879 C CB . TYR B 2 77 ? -81.681 -14.750 -14.158 1.00 108.99 ? 219 TYR G CB 1 ATOM 1880 C CG . TYR B 2 77 ? -81.148 -13.537 -14.894 1.00 108.99 ? 219 TYR G CG 1 ATOM 1881 C CD1 . TYR B 2 77 ? -80.510 -13.631 -16.136 1.00 108.99 ? 219 TYR G CD1 1 ATOM 1882 C CD2 . TYR B 2 77 ? -81.142 -12.294 -14.246 1.00 108.99 ? 219 TYR G CD2 1 ATOM 1883 C CE1 . TYR B 2 77 ? -79.886 -12.515 -16.714 1.00 108.99 ? 219 TYR G CE1 1 ATOM 1884 C CE2 . TYR B 2 77 ? -80.511 -11.188 -14.805 1.00 108.99 ? 219 TYR G CE2 1 ATOM 1885 C CZ . TYR B 2 77 ? -79.884 -11.301 -16.041 1.00 108.99 ? 219 TYR G CZ 1 ATOM 1886 O OH . TYR B 2 77 ? -79.240 -10.199 -16.564 1.00 108.99 ? 219 TYR G OH 1 ATOM 1887 N N . ALA B 2 78 ? -83.395 -17.529 -14.470 1.00 82.21 ? 220 ALA G N 1 ATOM 1888 C CA . ALA B 2 78 ? -83.722 -18.827 -13.875 1.00 82.21 ? 220 ALA G CA 1 ATOM 1889 C C . ALA B 2 78 ? -82.490 -19.692 -13.755 1.00 82.21 ? 220 ALA G C 1 ATOM 1890 O O . ALA B 2 78 ? -81.533 -19.570 -14.551 1.00 82.21 ? 220 ALA G O 1 ATOM 1891 C CB . ALA B 2 78 ? -84.726 -19.552 -14.723 1.00 133.37 ? 220 ALA G CB 1 ATOM 1892 N N . ILE B 2 79 ? -82.537 -20.577 -12.761 1.00 144.42 ? 221 ILE G N 1 ATOM 1893 C CA . ILE B 2 79 ? -81.429 -21.460 -12.457 1.00 144.42 ? 221 ILE G CA 1 ATOM 1894 C C . ILE B 2 79 ? -82.129 -22.733 -12.933 1.00 144.42 ? 221 ILE G C 1 ATOM 1895 O O . ILE B 2 79 ? -83.263 -23.007 -12.559 1.00 144.42 ? 221 ILE G O 1 ATOM 1896 C CB . ILE B 2 79 ? -81.188 -21.640 -10.900 1.00 107.18 ? 221 ILE G CB 1 ATOM 1897 C CG1 . ILE B 2 79 ? -80.870 -20.334 -10.140 1.00 107.18 ? 221 ILE G CG1 1 ATOM 1898 C CG2 . ILE B 2 79 ? -79.941 -22.506 -10.706 1.00 107.18 ? 221 ILE G CG2 1 ATOM 1899 C CD1 . ILE B 2 79 ? -79.673 -19.593 -10.577 1.00 107.18 ? 221 ILE G CD1 1 ATOM 1900 N N . LEU B 2 80 ? -81.450 -23.499 -13.767 1.00 93.37 ? 222 LEU G N 1 ATOM 1901 C CA . LEU B 2 80 ? -81.983 -24.744 -14.284 1.00 93.37 ? 222 LEU G CA 1 ATOM 1902 C C . LEU B 2 80 ? -81.210 -25.877 -13.663 1.00 93.37 ? 222 LEU G C 1 ATOM 1903 O O . LEU B 2 80 ? -80.112 -25.687 -13.225 1.00 93.37 ? 222 LEU G O 1 ATOM 1904 C CB . LEU B 2 80 ? -81.842 -24.859 -15.816 1.00 95.04 ? 222 LEU G CB 1 ATOM 1905 C CG . LEU B 2 80 ? -82.450 -23.906 -16.848 1.00 95.04 ? 222 LEU G CG 1 ATOM 1906 C CD1 . LEU B 2 80 ? -82.112 -24.316 -18.268 1.00 95.04 ? 222 LEU G CD1 1 ATOM 1907 C CD2 . LEU B 2 80 ? -83.938 -24.060 -16.736 1.00 95.04 ? 222 LEU G CD2 1 ATOM 1908 N N . LYS B 2 81 ? -81.844 -27.021 -13.484 1.00 126.39 ? 223 LYS G N 1 ATOM 1909 C CA . LYS B 2 81 ? -81.161 -28.223 -13.006 1.00 126.39 ? 223 LYS G CA 1 ATOM 1910 C C . LYS B 2 81 ? -81.204 -29.298 -14.050 1.00 126.39 ? 223 LYS G C 1 ATOM 1911 O O . LYS B 2 81 ? -82.047 -29.246 -14.928 1.00 126.39 ? 223 LYS G O 1 ATOM 1912 C CB . LYS B 2 81 ? -81.659 -28.835 -11.683 1.00 88.54 ? 223 LYS G CB 1 ATOM 1913 C CG . LYS B 2 81 ? -81.377 -28.044 -10.396 1.00 88.54 ? 223 LYS G CG 1 ATOM 1914 C CD . LYS B 2 81 ? -81.911 -28.728 -9.103 1.00 88.54 ? 223 LYS G CD 1 ATOM 1915 C CE . LYS B 2 81 ? -81.578 -27.863 -7.892 1.00 88.54 ? 223 LYS G CE 1 ATOM 1916 N NZ . LYS B 2 81 ? -81.930 -28.453 -6.563 1.00 88.54 ? 223 LYS G NZ 1 ATOM 1917 N N . CYS B 2 82 ? -80.205 -30.169 -14.092 1.00 118.72 ? 224 CYS G N 1 ATOM 1918 C CA . CYS B 2 82 ? -80.298 -31.259 -15.057 1.00 118.72 ? 224 CYS G CA 1 ATOM 1919 C C . CYS B 2 82 ? -80.771 -32.604 -14.430 1.00 118.72 ? 224 CYS G C 1 ATOM 1920 O O . CYS B 2 82 ? -80.241 -33.080 -13.436 1.00 118.72 ? 224 CYS G O 1 ATOM 1921 C CB . CYS B 2 82 ? -78.986 -31.437 -15.859 1.00 139.71 ? 224 CYS G CB 1 ATOM 1922 S SG . CYS B 2 82 ? -78.832 -32.944 -16.920 1.00 139.71 ? 224 CYS G SG 1 ATOM 1923 N N . ASN B 2 83 ? -81.882 -33.111 -14.978 1.00 187.81 ? 225 ASN G N 1 ATOM 1924 C CA . ASN B 2 83 ? -82.524 -34.403 -14.652 1.00 187.81 ? 225 ASN G CA 1 ATOM 1925 C C . ASN B 2 83 ? -81.801 -35.729 -14.821 1.00 187.81 ? 225 ASN G C 1 ATOM 1926 O O . ASN B 2 83 ? -81.901 -36.577 -13.951 1.00 187.81 ? 225 ASN G O 1 ATOM 1927 C CB . ASN B 2 83 ? -83.920 -34.596 -15.331 1.00 102.80 ? 225 ASN G CB 1 ATOM 1928 C CG . ASN B 2 83 ? -85.006 -33.694 -14.768 1.00 102.80 ? 225 ASN G CG 1 ATOM 1929 O OD1 . ASN B 2 83 ? -85.699 -33.028 -15.535 1.00 102.80 ? 225 ASN G OD1 1 ATOM 1930 N ND2 . ASN B 2 83 ? -85.170 -33.687 -13.431 1.00 102.80 ? 225 ASN G ND2 1 ATOM 1931 N N . ASP B 2 84 ? -81.028 -35.909 -15.890 1.00 121.30 ? 226 ASP G N 1 ATOM 1932 C CA . ASP B 2 84 ? -80.532 -37.249 -16.149 1.00 121.30 ? 226 ASP G CA 1 ATOM 1933 C C . ASP B 2 84 ? -79.735 -37.561 -14.906 1.00 121.30 ? 226 ASP G C 1 ATOM 1934 O O . ASP B 2 84 ? -79.041 -36.706 -14.355 1.00 121.30 ? 226 ASP G O 1 ATOM 1935 C CB . ASP B 2 84 ? -79.581 -37.195 -17.361 1.00 121.33 ? 226 ASP G CB 1 ATOM 1936 C CG . ASP B 2 84 ? -80.302 -36.917 -18.708 1.00 121.33 ? 226 ASP G CG 1 ATOM 1937 O OD1 . ASP B 2 84 ? -81.508 -37.196 -18.818 1.00 121.33 ? 226 ASP G OD1 1 ATOM 1938 O OD2 . ASP B 2 84 ? -79.664 -36.381 -19.657 1.00 121.33 ? 226 ASP G OD2 1 ATOM 1939 N N . LYS B 2 85 ? -79.874 -38.809 -14.461 1.00 213.26 ? 227 LYS G N 1 ATOM 1940 C CA . LYS B 2 85 ? -79.223 -39.311 -13.246 1.00 213.26 ? 227 LYS G CA 1 ATOM 1941 C C . LYS B 2 85 ? -77.681 -39.251 -13.252 1.00 213.26 ? 227 LYS G C 1 ATOM 1942 O O . LYS B 2 85 ? -77.058 -38.924 -12.246 1.00 213.26 ? 227 LYS G O 1 ATOM 1943 C CB . LYS B 2 85 ? -79.819 -40.690 -12.855 1.00 130.48 ? 227 LYS G CB 1 ATOM 1944 C CG . LYS B 2 85 ? -81.334 -40.603 -12.316 1.00 130.48 ? 227 LYS G CG 1 ATOM 1945 C CD . LYS B 2 85 ? -81.537 -39.720 -11.040 1.00 130.48 ? 227 LYS G CD 1 ATOM 1946 C CE . LYS B 2 85 ? -82.990 -39.636 -10.523 1.00 130.48 ? 227 LYS G CE 1 ATOM 1947 N NZ . LYS B 2 85 ? -83.554 -40.910 -10.065 1.00 130.48 ? 227 LYS G NZ 1 ATOM 1948 N N . THR B 2 86 ? -77.056 -39.562 -14.379 1.00 147.86 ? 228 THR G N 1 ATOM 1949 C CA . THR B 2 86 ? -75.616 -39.411 -14.429 1.00 147.86 ? 228 THR G CA 1 ATOM 1950 C C . THR B 2 86 ? -75.465 -38.554 -15.679 1.00 147.86 ? 228 THR G C 1 ATOM 1951 O O . THR B 2 86 ? -76.191 -38.711 -16.663 1.00 147.86 ? 228 THR G O 1 ATOM 1952 C CB . THR B 2 86 ? -74.920 -40.764 -14.639 1.00 169.66 ? 228 THR G CB 1 ATOM 1953 O OG1 . THR B 2 86 ? -75.471 -41.396 -15.801 1.00 169.66 ? 228 THR G OG1 1 ATOM 1954 C CG2 . THR B 2 86 ? -75.067 -41.654 -13.428 1.00 169.66 ? 228 THR G CG2 1 ATOM 1955 N N . PHE B 2 87 ? -74.555 -37.597 -15.618 1.00 176.68 ? 229 PHE G N 1 ATOM 1956 C CA . PHE B 2 87 ? -74.352 -36.716 -16.751 1.00 176.68 ? 229 PHE G CA 1 ATOM 1957 C C . PHE B 2 87 ? -72.839 -36.478 -16.869 1.00 176.68 ? 229 PHE G C 1 ATOM 1958 O O . PHE B 2 87 ? -72.199 -36.141 -15.869 1.00 176.68 ? 229 PHE G O 1 ATOM 1959 C CB . PHE B 2 87 ? -75.222 -35.474 -16.457 1.00 113.03 ? 229 PHE G CB 1 ATOM 1960 C CG . PHE B 2 87 ? -75.187 -34.406 -17.485 1.00 113.03 ? 229 PHE G CG 1 ATOM 1961 C CD1 . PHE B 2 87 ? -74.263 -33.371 -17.442 1.00 113.03 ? 229 PHE G CD1 1 ATOM 1962 C CD2 . PHE B 2 87 ? -76.121 -34.432 -18.494 1.00 113.03 ? 229 PHE G CD2 1 ATOM 1963 C CE1 . PHE B 2 87 ? -74.277 -32.374 -18.390 1.00 113.03 ? 229 PHE G CE1 1 ATOM 1964 C CE2 . PHE B 2 87 ? -76.149 -33.453 -19.448 1.00 113.03 ? 229 PHE G CE2 1 ATOM 1965 C CZ . PHE B 2 87 ? -75.223 -32.413 -19.398 1.00 113.03 ? 229 PHE G CZ 1 ATOM 1966 N N . ASN B 2 88 ? -72.236 -36.640 -18.038 1.00 134.54 ? 230 ASN G N 1 ATOM 1967 C CA . ASN B 2 88 ? -70.805 -36.355 -18.102 1.00 134.54 ? 230 ASN G CA 1 ATOM 1968 C C . ASN B 2 88 ? -70.794 -34.828 -18.209 1.00 134.54 ? 230 ASN G C 1 ATOM 1969 O O . ASN B 2 88 ? -71.829 -34.219 -18.489 1.00 134.54 ? 230 ASN G O 1 ATOM 1970 C CB . ASN B 2 88 ? -70.104 -37.052 -19.269 1.00 114.04 ? 230 ASN G CB 1 ATOM 1971 C CG . ASN B 2 88 ? -70.503 -36.482 -20.584 1.00 114.04 ? 230 ASN G CG 1 ATOM 1972 O OD1 . ASN B 2 88 ? -71.562 -35.845 -20.693 1.00 114.04 ? 230 ASN G OD1 1 ATOM 1973 N ND2 . ASN B 2 88 ? -69.654 -36.666 -21.599 1.00 114.04 ? 230 ASN G ND2 1 ATOM 1974 N N . GLY B 2 89 ? -69.630 -34.212 -18.084 1.00 127.83 ? 231 GLY G N 1 ATOM 1975 C CA . GLY B 2 89 ? -69.561 -32.762 -17.993 1.00 127.83 ? 231 GLY G CA 1 ATOM 1976 C C . GLY B 2 89 ? -70.119 -32.027 -19.176 1.00 127.83 ? 231 GLY G C 1 ATOM 1977 O O . GLY B 2 89 ? -70.803 -31.023 -18.990 1.00 127.83 ? 231 GLY G O 1 ATOM 1978 N N . ILE B 2 90 ? -69.880 -32.508 -20.379 1.00 120.81 ? 232 ILE G N 1 ATOM 1979 C CA . ILE B 2 90 ? -70.426 -31.793 -21.496 1.00 120.81 ? 232 ILE G CA 1 ATOM 1980 C C . ILE B 2 90 ? -71.315 -32.803 -22.147 1.00 120.81 ? 232 ILE G C 1 ATOM 1981 O O . ILE B 2 90 ? -70.898 -33.867 -22.598 1.00 120.81 ? 232 ILE G O 1 ATOM 1982 C CB . ILE B 2 90 ? -69.312 -31.421 -22.489 1.00 100.84 ? 232 ILE G CB 1 ATOM 1983 C CG1 . ILE B 2 90 ? -68.294 -30.553 -21.805 1.00 100.84 ? 232 ILE G CG1 1 ATOM 1984 C CG2 . ILE B 2 90 ? -69.870 -30.767 -23.721 1.00 100.84 ? 232 ILE G CG2 1 ATOM 1985 C CD1 . ILE B 2 90 ? -68.939 -29.378 -21.167 1.00 100.84 ? 232 ILE G CD1 1 ATOM 1986 N N . GLY B 2 91 ? -72.580 -32.413 -22.193 1.00 146.61 ? 233 GLY G N 1 ATOM 1987 C CA . GLY B 2 91 ? -73.588 -33.252 -22.775 1.00 146.61 ? 233 GLY G CA 1 ATOM 1988 C C . GLY B 2 91 ? -74.910 -32.565 -23.034 1.00 146.61 ? 233 GLY G C 1 ATOM 1989 O O . GLY B 2 91 ? -75.246 -31.528 -22.441 1.00 146.61 ? 233 GLY G O 1 ATOM 1990 N N . PRO B 2 92 ? -75.682 -33.135 -23.954 1.00 103.18 ? 234 PRO G N 1 ATOM 1991 C CA . PRO B 2 92 ? -76.990 -32.568 -24.258 1.00 103.18 ? 234 PRO G CA 1 ATOM 1992 C C . PRO B 2 92 ? -77.759 -33.230 -23.112 1.00 103.18 ? 234 PRO G C 1 ATOM 1993 O O . PRO B 2 92 ? -77.613 -34.441 -22.905 1.00 103.18 ? 234 PRO G O 1 ATOM 1994 C CB . PRO B 2 92 ? -77.304 -33.165 -25.624 1.00 93.14 ? 234 PRO G CB 1 ATOM 1995 C CG . PRO B 2 92 ? -75.910 -33.416 -26.218 1.00 93.14 ? 234 PRO G CG 1 ATOM 1996 C CD . PRO B 2 92 ? -75.204 -34.009 -25.039 1.00 93.14 ? 234 PRO G CD 1 ATOM 1997 N N . CYS B 2 93 ? -78.512 -32.469 -22.318 1.00 128.16 ? 235 CYS G N 1 ATOM 1998 C CA . CYS B 2 93 ? -79.238 -33.111 -21.213 1.00 128.16 ? 235 CYS G CA 1 ATOM 1999 C C . CYS B 2 93 ? -80.715 -33.334 -21.600 1.00 128.16 ? 235 CYS G C 1 ATOM 2000 O O . CYS B 2 93 ? -81.471 -32.376 -21.850 1.00 128.16 ? 235 CYS G O 1 ATOM 2001 C CB . CYS B 2 93 ? -79.142 -32.213 -19.957 1.00 200.20 ? 235 CYS G CB 1 ATOM 2002 S SG . CYS B 2 93 ? -80.109 -32.769 -18.509 1.00 200.20 ? 235 CYS G SG 1 ATOM 2003 N N . ASN B 2 94 ? -81.117 -34.612 -21.612 1.00 177.24 ? 236 ASN G N 1 ATOM 2004 C CA . ASN B 2 94 ? -82.492 -34.980 -21.981 1.00 177.24 ? 236 ASN G CA 1 ATOM 2005 C C . ASN B 2 94 ? -83.670 -34.449 -21.168 1.00 177.24 ? 236 ASN G C 1 ATOM 2006 O O . ASN B 2 94 ? -84.697 -34.063 -21.731 1.00 177.24 ? 236 ASN G O 1 ATOM 2007 C CB . ASN B 2 94 ? -82.661 -36.534 -22.103 1.00 103.94 ? 236 ASN G CB 1 ATOM 2008 C CG . ASN B 2 94 ? -81.996 -37.142 -23.357 1.00 103.94 ? 236 ASN G CG 1 ATOM 2009 O OD1 . ASN B 2 94 ? -81.723 -38.343 -23.414 1.00 103.94 ? 236 ASN G OD1 1 ATOM 2010 N ND2 . ASN B 2 94 ? -81.789 -36.318 -24.373 1.00 103.94 ? 236 ASN G ND2 1 ATOM 2011 N N . ASN B 2 95 ? -83.529 -34.400 -19.851 1.00 120.63 ? 237 ASN G N 1 ATOM 2012 C CA . ASN B 2 95 ? -84.660 -33.961 -19.041 1.00 120.63 ? 237 ASN G CA 1 ATOM 2013 C C . ASN B 2 95 ? -84.280 -32.785 -18.117 1.00 120.63 ? 237 ASN G C 1 ATOM 2014 O O . ASN B 2 95 ? -83.270 -32.844 -17.451 1.00 120.63 ? 237 ASN G O 1 ATOM 2015 C CB . ASN B 2 95 ? -85.141 -35.200 -18.294 1.00 158.84 ? 237 ASN G CB 1 ATOM 2016 C CG . ASN B 2 95 ? -85.799 -36.200 -19.236 1.00 158.84 ? 237 ASN G CG 1 ATOM 2017 O OD1 . ASN B 2 95 ? -86.230 -35.837 -20.332 1.00 158.84 ? 237 ASN G OD1 1 ATOM 2018 N ND2 . ASN B 2 95 ? -85.829 -37.471 -18.837 1.00 158.84 ? 237 ASN G ND2 1 ATOM 2019 N N . VAL B 2 96 ? -85.060 -31.712 -18.110 1.00 159.30 ? 238 VAL G N 1 ATOM 2020 C CA . VAL B 2 96 ? -84.765 -30.523 -17.299 1.00 159.30 ? 238 VAL G CA 1 ATOM 2021 C C . VAL B 2 96 ? -85.818 -29.852 -16.361 1.00 159.30 ? 238 VAL G C 1 ATOM 2022 O O . VAL B 2 96 ? -86.958 -29.672 -16.744 1.00 159.30 ? 238 VAL G O 1 ATOM 2023 C CB . VAL B 2 96 ? -84.077 -29.454 -18.153 1.00 94.37 ? 238 VAL G CB 1 ATOM 2024 C CG1 . VAL B 2 96 ? -83.780 -28.216 -17.274 1.00 94.37 ? 238 VAL G CG1 1 ATOM 2025 C CG2 . VAL B 2 96 ? -82.830 -30.042 -18.842 1.00 94.37 ? 238 VAL G CG2 1 ATOM 2026 N N . SER B 2 97 ? -85.463 -29.596 -15.114 1.00 97.32 ? 239 SER G N 1 ATOM 2027 C CA . SER B 2 97 ? -86.298 -28.917 -14.070 1.00 97.32 ? 239 SER G CA 1 ATOM 2028 C C . SER B 2 97 ? -85.826 -27.471 -13.857 1.00 97.32 ? 239 SER G C 1 ATOM 2029 O O . SER B 2 97 ? -84.868 -27.066 -14.502 1.00 97.32 ? 239 SER G O 1 ATOM 2030 C CB . SER B 2 97 ? -86.261 -29.653 -12.696 1.00 98.68 ? 239 SER G CB 1 ATOM 2031 O OG . SER B 2 97 ? -86.985 -28.956 -11.669 1.00 98.68 ? 239 SER G OG 1 ATOM 2032 N N . THR B 2 98 ? -86.564 -26.649 -13.104 1.00 131.13 ? 240 THR G N 1 ATOM 2033 C CA . THR B 2 98 ? -86.072 -25.287 -12.859 1.00 131.13 ? 240 THR G CA 1 ATOM 2034 C C . THR B 2 98 ? -86.157 -25.065 -11.342 1.00 131.13 ? 240 THR G C 1 ATOM 2035 O O . THR B 2 98 ? -87.169 -25.450 -10.717 1.00 131.13 ? 240 THR G O 1 ATOM 2036 C CB . THR B 2 98 ? -86.956 -24.216 -13.565 1.00 94.50 ? 240 THR G CB 1 ATOM 2037 O OG1 . THR B 2 98 ? -86.310 -22.937 -13.493 1.00 94.50 ? 240 THR G OG1 1 ATOM 2038 C CG2 . THR B 2 98 ? -88.362 -24.091 -12.850 1.00 94.50 ? 240 THR G CG2 1 ATOM 2039 N N . VAL B 2 99 ? -85.136 -24.390 -10.775 1.00 82.58 ? 241 VAL G N 1 ATOM 2040 C CA . VAL B 2 99 ? -85.082 -24.146 -9.307 1.00 82.58 ? 241 VAL G CA 1 ATOM 2041 C C . VAL B 2 99 ? -84.824 -22.724 -8.903 1.00 82.58 ? 241 VAL G C 1 ATOM 2042 O O . VAL B 2 99 ? -84.040 -22.042 -9.503 1.00 82.58 ? 241 VAL G O 1 ATOM 2043 C CB . VAL B 2 99 ? -83.930 -24.951 -8.597 1.00 88.34 ? 241 VAL G CB 1 ATOM 2044 C CG1 . VAL B 2 99 ? -84.205 -26.452 -8.563 1.00 88.34 ? 241 VAL G CG1 1 ATOM 2045 C CG2 . VAL B 2 99 ? -82.669 -24.731 -9.343 1.00 88.34 ? 241 VAL G CG2 1 ATOM 2046 N N . GLN B 2 100 ? -85.521 -22.286 -7.866 1.00 180.30 ? 242 GLN G N 1 ATOM 2047 C CA . GLN B 2 100 ? -85.350 -20.933 -7.404 1.00 180.30 ? 242 GLN G CA 1 ATOM 2048 C C . GLN B 2 100 ? -83.924 -20.600 -6.958 1.00 180.30 ? 242 GLN G C 1 ATOM 2049 O O . GLN B 2 100 ? -83.372 -19.569 -7.333 1.00 180.30 ? 242 GLN G O 1 ATOM 2050 C CB . GLN B 2 100 ? -86.378 -20.676 -6.298 1.00 122.21 ? 242 GLN G CB 1 ATOM 2051 C CG . GLN B 2 100 ? -86.301 -19.288 -5.729 1.00 122.21 ? 242 GLN G CG 1 ATOM 2052 C CD . GLN B 2 100 ? -87.405 -18.967 -4.742 1.00 122.21 ? 242 GLN G CD 1 ATOM 2053 O OE1 . GLN B 2 100 ? -88.382 -19.732 -4.575 1.00 122.21 ? 242 GLN G OE1 1 ATOM 2054 N NE2 . GLN B 2 100 ? -87.279 -17.798 -4.104 1.00 122.21 ? 242 GLN G NE2 1 ATOM 2055 N N . CYS B 2 101 ? -83.325 -21.505 -6.189 1.00 114.82 ? 243 CYS G N 1 ATOM 2056 C CA . CYS B 2 101 ? -81.948 -21.389 -5.684 1.00 114.82 ? 243 CYS G CA 1 ATOM 2057 C C . CYS B 2 101 ? -81.017 -22.549 -5.866 1.00 114.82 ? 243 CYS G C 1 ATOM 2058 O O . CYS B 2 101 ? -81.436 -23.698 -5.938 1.00 114.82 ? 243 CYS G O 1 ATOM 2059 C CB . CYS B 2 101 ? -81.819 -20.989 -4.196 1.00 135.72 ? 243 CYS G CB 1 ATOM 2060 S SG . CYS B 2 101 ? -82.498 -19.413 -3.610 1.00 135.72 ? 243 CYS G SG 1 ATOM 2061 N N . THR B 2 102 ? -79.730 -22.247 -5.926 1.00 166.69 ? 244 THR G N 1 ATOM 2062 C CA . THR B 2 102 ? -78.754 -23.307 -5.980 1.00 166.69 ? 244 THR G CA 1 ATOM 2063 C C . THR B 2 102 ? -78.902 -23.809 -4.554 1.00 166.69 ? 244 THR G C 1 ATOM 2064 O O . THR B 2 102 ? -79.359 -23.064 -3.685 1.00 166.69 ? 244 THR G O 1 ATOM 2065 C CB . THR B 2 102 ? -77.359 -22.760 -6.169 1.00 62.13 ? 244 THR G CB 1 ATOM 2066 O OG1 . THR B 2 102 ? -77.069 -21.850 -5.092 1.00 62.13 ? 244 THR G OG1 1 ATOM 2067 C CG2 . THR B 2 102 ? -77.196 -22.109 -7.526 1.00 62.13 ? 244 THR G CG2 1 ATOM 2068 N N . HIS B 2 103 ? -78.476 -25.035 -4.292 1.00 124.51 ? 245 HIS G N 1 ATOM 2069 C CA . HIS B 2 103 ? -78.632 -25.621 -2.953 1.00 124.51 ? 245 HIS G CA 1 ATOM 2070 C C . HIS B 2 103 ? -77.565 -25.129 -2.015 1.00 124.51 ? 245 HIS G C 1 ATOM 2071 O O . HIS B 2 103 ? -76.734 -24.306 -2.412 1.00 124.51 ? 245 HIS G O 1 ATOM 2072 C CB . HIS B 2 103 ? -78.646 -27.166 -2.977 1.00 121.60 ? 245 HIS G CB 1 ATOM 2073 C CG . HIS B 2 103 ? -77.372 -27.809 -3.449 1.00 121.60 ? 245 HIS G CG 1 ATOM 2074 N ND1 . HIS B 2 103 ? -77.040 -27.928 -4.783 1.00 121.60 ? 245 HIS G ND1 1 ATOM 2075 C CD2 . HIS B 2 103 ? -76.365 -28.393 -2.757 1.00 121.60 ? 245 HIS G CD2 1 ATOM 2076 C CE1 . HIS B 2 103 ? -75.884 -28.557 -4.890 1.00 121.60 ? 245 HIS G CE1 1 ATOM 2077 N NE2 . HIS B 2 103 ? -75.452 -28.849 -3.676 1.00 121.60 ? 245 HIS G NE2 1 ATOM 2078 N N . GLY B 2 104 ? -77.660 -25.497 -0.740 1.00 128.53 ? 246 GLY G N 1 ATOM 2079 C CA . GLY B 2 104 ? -76.628 -25.020 0.157 1.00 128.53 ? 246 GLY G CA 1 ATOM 2080 C C . GLY B 2 104 ? -75.322 -25.583 -0.347 1.00 128.53 ? 246 GLY G C 1 ATOM 2081 O O . GLY B 2 104 ? -75.221 -26.759 -0.680 1.00 128.53 ? 246 GLY G O 1 ATOM 2082 N N . ILE B 2 105 ? -74.314 -24.737 -0.401 1.00 96.79 ? 247 ILE G N 1 ATOM 2083 C CA . ILE B 2 105 ? -73.013 -25.156 -0.863 1.00 96.79 ? 247 ILE G CA 1 ATOM 2084 C C . ILE B 2 105 ? -72.061 -24.932 0.230 1.00 96.79 ? 247 ILE G C 1 ATOM 2085 O O . ILE B 2 105 ? -72.124 -23.875 0.886 1.00 96.79 ? 247 ILE G O 1 ATOM 2086 C CB . ILE B 2 105 ? -72.517 -24.432 -2.217 1.00 61.60 ? 247 ILE G CB 1 ATOM 2087 C CG1 . ILE B 2 105 ? -73.495 -24.725 -3.334 1.00 61.60 ? 247 ILE G CG1 1 ATOM 2088 C CG2 . ILE B 2 105 ? -71.121 -24.849 -2.641 1.00 61.60 ? 247 ILE G CG2 1 ATOM 2089 C CD1 . ILE B 2 105 ? -73.649 -26.214 -3.557 1.00 61.60 ? 247 ILE G CD1 1 ATOM 2090 N N . LYS B 2 106 ? -71.285 -25.980 0.518 1.00 97.66 ? 248 LYS G N 1 ATOM 2091 C CA . LYS B 2 106 ? -70.224 -25.885 1.512 1.00 97.66 ? 248 LYS G CA 1 ATOM 2092 C C . LYS B 2 106 ? -68.993 -25.691 0.621 1.00 97.66 ? 248 LYS G C 1 ATOM 2093 O O . LYS B 2 106 ? -68.698 -26.498 -0.251 1.00 97.66 ? 248 LYS G O 1 ATOM 2094 C CB . LYS B 2 106 ? -70.155 -27.164 2.368 1.00 105.13 ? 248 LYS G CB 1 ATOM 2095 C CG . LYS B 2 106 ? -71.444 -27.459 3.127 1.00 105.13 ? 248 LYS G CG 1 ATOM 2096 C CD . LYS B 2 106 ? -71.175 -27.925 4.545 1.00 105.13 ? 248 LYS G CD 1 ATOM 2097 C CE . LYS B 2 106 ? -70.477 -26.857 5.405 1.00 105.13 ? 248 LYS G CE 1 ATOM 2098 N NZ . LYS B 2 106 ? -70.394 -27.230 6.870 1.00 105.13 ? 248 LYS G NZ 1 ATOM 2099 N N . PRO B 2 107 ? -68.304 -24.578 0.800 1.00 107.57 ? 249 PRO G N 1 ATOM 2100 C CA . PRO B 2 107 ? -67.116 -24.201 0.064 1.00 107.57 ? 249 PRO G CA 1 ATOM 2101 C C . PRO B 2 107 ? -65.853 -24.528 0.861 1.00 107.57 ? 249 PRO G C 1 ATOM 2102 O O . PRO B 2 107 ? -65.556 -23.930 1.911 1.00 107.57 ? 249 PRO G O 1 ATOM 2103 C CB . PRO B 2 107 ? -67.321 -22.724 -0.119 1.00 66.88 ? 249 PRO G CB 1 ATOM 2104 C CG . PRO B 2 107 ? -67.874 -22.330 1.167 1.00 66.88 ? 249 PRO G CG 1 ATOM 2105 C CD . PRO B 2 107 ? -68.744 -23.483 1.661 1.00 66.88 ? 249 PRO G CD 1 ATOM 2106 N N . VAL B 2 108 ? -65.092 -25.474 0.340 1.00 97.27 ? 250 VAL G N 1 ATOM 2107 C CA . VAL B 2 108 ? -63.857 -25.913 0.975 1.00 97.27 ? 250 VAL G CA 1 ATOM 2108 C C . VAL B 2 108 ? -62.872 -25.616 -0.080 1.00 97.27 ? 250 VAL G C 1 ATOM 2109 O O . VAL B 2 108 ? -63.196 -25.833 -1.276 1.00 97.27 ? 250 VAL G O 1 ATOM 2110 C CB . VAL B 2 108 ? -63.878 -27.392 1.214 1.00 81.45 ? 250 VAL G CB 1 ATOM 2111 C CG1 . VAL B 2 108 ? -64.897 -27.716 2.323 1.00 81.45 ? 250 VAL G CG1 1 ATOM 2112 C CG2 . VAL B 2 108 ? -64.304 -28.093 -0.150 1.00 81.45 ? 250 VAL G CG2 1 ATOM 2113 N N . VAL B 2 109 ? -61.664 -25.193 0.338 1.00 109.52 ? 251 VAL G N 1 ATOM 2114 C CA . VAL B 2 109 ? -60.685 -24.767 -0.658 1.00 109.52 ? 251 VAL G CA 1 ATOM 2115 C C . VAL B 2 109 ? -59.866 -25.996 -0.352 1.00 109.52 ? 251 VAL G C 1 ATOM 2116 O O . VAL B 2 109 ? -59.486 -26.235 0.795 1.00 109.52 ? 251 VAL G O 1 ATOM 2117 C CB . VAL B 2 109 ? -59.917 -23.467 -0.215 1.00 52.05 ? 251 VAL G CB 1 ATOM 2118 C CG1 . VAL B 2 109 ? -58.956 -23.076 -1.289 1.00 52.05 ? 251 VAL G CG1 1 ATOM 2119 C CG2 . VAL B 2 109 ? -60.867 -22.358 0.241 1.00 52.05 ? 251 VAL G CG2 1 ATOM 2120 N N . SER B 2 110 ? -59.685 -26.792 -1.391 1.00 103.50 ? 252 SER G N 1 ATOM 2121 C CA . SER B 2 110 ? -59.016 -28.073 -1.317 1.00 103.50 ? 252 SER G CA 1 ATOM 2122 C C . SER B 2 110 ? -58.271 -28.545 -2.562 1.00 103.50 ? 252 SER G C 1 ATOM 2123 O O . SER B 2 110 ? -58.544 -28.090 -3.667 1.00 103.50 ? 252 SER G O 1 ATOM 2124 C CB . SER B 2 110 ? -60.001 -29.139 -0.883 1.00 83.89 ? 252 SER G CB 1 ATOM 2125 O OG . SER B 2 110 ? -59.336 -30.365 -0.730 1.00 83.89 ? 252 SER G OG 1 ATOM 2126 N N . THR B 2 111 ? -57.346 -29.477 -2.381 1.00 72.49 ? 253 THR G N 1 ATOM 2127 C CA . THR B 2 111 ? -56.586 -30.013 -3.489 1.00 72.49 ? 253 THR G CA 1 ATOM 2128 C C . THR B 2 111 ? -56.495 -31.490 -3.439 1.00 72.49 ? 253 THR G C 1 ATOM 2129 O O . THR B 2 111 ? -56.609 -32.071 -2.372 1.00 72.49 ? 253 THR G O 1 ATOM 2130 C CB . THR B 2 111 ? -55.218 -29.591 -3.562 1.00 74.55 ? 253 THR G CB 1 ATOM 2131 O OG1 . THR B 2 111 ? -54.673 -30.238 -4.722 1.00 74.55 ? 253 THR G OG1 1 ATOM 2132 C CG2 . THR B 2 111 ? -54.460 -30.009 -2.332 1.00 74.55 ? 253 THR G CG2 1 ATOM 2133 N N . GLN B 2 112 ? -56.260 -32.089 -4.607 1.00 91.90 ? 254 GLN G N 1 ATOM 2134 C CA . GLN B 2 112 ? -56.317 -33.519 -4.735 1.00 91.90 ? 254 GLN G CA 1 ATOM 2135 C C . GLN B 2 112 ? -57.518 -34.213 -3.917 1.00 91.90 ? 254 GLN G C 1 ATOM 2136 O O . GLN B 2 112 ? -57.868 -35.378 -4.134 1.00 91.90 ? 254 GLN G O 1 ATOM 2137 C CB . GLN B 2 112 ? -54.893 -34.013 -4.448 1.00 73.41 ? 254 GLN G CB 1 ATOM 2138 C CG . GLN B 2 112 ? -54.457 -33.867 -2.982 1.00 73.41 ? 254 GLN G CG 1 ATOM 2139 C CD . GLN B 2 112 ? -53.010 -34.354 -2.637 1.00 73.41 ? 254 GLN G CD 1 ATOM 2140 O OE1 . GLN B 2 112 ? -52.007 -34.059 -3.310 1.00 73.41 ? 254 GLN G OE1 1 ATOM 2141 N NE2 . GLN B 2 112 ? -52.922 -35.076 -1.544 1.00 73.41 ? 254 GLN G NE2 1 ATOM 2142 N N . LEU B 2 113 ? -58.167 -33.512 -2.992 1.00 126.30 ? 255 LEU G N 1 ATOM 2143 C CA . LEU B 2 113 ? -59.381 -34.034 -2.340 1.00 126.30 ? 255 LEU G CA 1 ATOM 2144 C C . LEU B 2 113 ? -60.461 -32.949 -2.324 1.00 126.30 ? 255 LEU G C 1 ATOM 2145 O O . LEU B 2 113 ? -60.134 -31.763 -2.266 1.00 126.30 ? 255 LEU G O 1 ATOM 2146 C CB . LEU B 2 113 ? -59.104 -34.538 -0.940 1.00 70.30 ? 255 LEU G CB 1 ATOM 2147 C CG . LEU B 2 113 ? -58.081 -35.679 -0.837 1.00 70.30 ? 255 LEU G CG 1 ATOM 2148 C CD1 . LEU B 2 113 ? -57.868 -36.119 0.653 1.00 70.30 ? 255 LEU G CD1 1 ATOM 2149 C CD2 . LEU B 2 113 ? -58.618 -36.853 -1.686 1.00 70.30 ? 255 LEU G CD2 1 ATOM 2150 N N . LEU B 2 114 ? -61.733 -33.355 -2.365 1.00 82.21 ? 256 LEU G N 1 ATOM 2151 C CA . LEU B 2 114 ? -62.894 -32.448 -2.393 1.00 82.21 ? 256 LEU G CA 1 ATOM 2152 C C . LEU B 2 114 ? -63.480 -32.790 -1.043 1.00 82.21 ? 256 LEU G C 1 ATOM 2153 O O . LEU B 2 114 ? -63.651 -33.953 -0.780 1.00 82.21 ? 256 LEU G O 1 ATOM 2154 C CB . LEU B 2 114 ? -63.686 -32.945 -3.593 1.00 90.55 ? 256 LEU G CB 1 ATOM 2155 C CG . LEU B 2 114 ? -62.908 -32.614 -4.875 1.00 90.55 ? 256 LEU G CG 1 ATOM 2156 C CD1 . LEU B 2 114 ? -63.485 -33.267 -6.041 1.00 90.55 ? 256 LEU G CD1 1 ATOM 2157 C CD2 . LEU B 2 114 ? -63.025 -31.112 -5.141 1.00 90.55 ? 256 LEU G CD2 1 ATOM 2158 N N . LEU B 2 115 ? -63.833 -31.811 -0.215 1.00 146.84 ? 257 LEU G N 1 ATOM 2159 C CA . LEU B 2 115 ? -64.281 -32.079 1.176 1.00 146.84 ? 257 LEU G CA 1 ATOM 2160 C C . LEU B 2 115 ? -65.694 -31.701 1.755 1.00 146.84 ? 257 LEU G C 1 ATOM 2161 O O . LEU B 2 115 ? -66.210 -30.642 1.448 1.00 146.84 ? 257 LEU G O 1 ATOM 2162 C CB . LEU B 2 115 ? -63.198 -31.500 2.078 1.00 84.25 ? 257 LEU G CB 1 ATOM 2163 C CG . LEU B 2 115 ? -61.829 -32.125 1.855 1.00 84.25 ? 257 LEU G CG 1 ATOM 2164 C CD1 . LEU B 2 115 ? -60.860 -31.493 2.777 1.00 84.25 ? 257 LEU G CD1 1 ATOM 2165 C CD2 . LEU B 2 115 ? -61.879 -33.589 2.075 1.00 84.25 ? 257 LEU G CD2 1 ATOM 2166 N N . ASN B 2 116 ? -66.301 -32.551 2.601 1.00 141.68 ? 258 ASN G N 1 ATOM 2167 C CA . ASN B 2 116 ? -67.645 -32.315 3.211 1.00 141.68 ? 258 ASN G CA 1 ATOM 2168 C C . ASN B 2 116 ? -68.668 -31.912 1.995 1.00 141.68 ? 258 ASN G C 1 ATOM 2169 O O . ASN B 2 116 ? -69.511 -31.015 2.151 1.00 141.68 ? 258 ASN G O 1 ATOM 2170 C CB . ASN B 2 116 ? -67.784 -31.335 4.594 1.00 97.02 ? 258 ASN G CB 1 ATOM 2171 C CG . ASN B 2 116 ? -67.144 -31.944 6.147 1.00 97.02 ? 258 ASN G CG 1 ATOM 2172 O OD1 . ASN B 2 116 ? -66.951 -33.170 6.239 1.00 97.02 ? 258 ASN G OD1 1 ATOM 2173 N ND2 . ASN B 2 116 ? -67.224 -31.155 7.339 1.00 97.02 ? 258 ASN G ND2 1 ATOM 2174 N N . GLY B 2 117 ? -68.581 -32.582 0.813 1.00 113.95 ? 259 GLY G N 1 ATOM 2175 C CA . GLY B 2 117 ? -69.416 -32.285 -0.382 1.00 113.95 ? 259 GLY G CA 1 ATOM 2176 C C . GLY B 2 117 ? -70.740 -32.982 -0.788 1.00 113.95 ? 259 GLY G C 1 ATOM 2177 O O . GLY B 2 117 ? -71.658 -33.134 0.019 1.00 113.95 ? 259 GLY G O 1 ATOM 2178 N N . SER B 2 118 ? -70.836 -33.374 -2.070 1.00 127.96 ? 260 SER G N 1 ATOM 2179 C CA . SER B 2 118 ? -72.019 -34.046 -2.653 1.00 127.96 ? 260 SER G CA 1 ATOM 2180 C C . SER B 2 118 ? -71.582 -35.320 -3.396 1.00 127.96 ? 260 SER G C 1 ATOM 2181 O O . SER B 2 118 ? -70.563 -35.326 -4.084 1.00 127.96 ? 260 SER G O 1 ATOM 2182 C CB . SER B 2 118 ? -72.742 -33.107 -3.619 1.00 169.13 ? 260 SER G CB 1 ATOM 2183 O OG . SER B 2 118 ? -73.175 -31.944 -2.941 1.00 169.13 ? 260 SER G OG 1 ATOM 2184 N N . LEU B 2 119 ? -72.380 -36.379 -3.254 1.00 134.66 ? 261 LEU G N 1 ATOM 2185 C CA . LEU B 2 119 ? -72.067 -37.699 -3.791 1.00 134.66 ? 261 LEU G CA 1 ATOM 2186 C C . LEU B 2 119 ? -72.878 -38.145 -5.033 1.00 134.66 ? 261 LEU G C 1 ATOM 2187 O O . LEU B 2 119 ? -74.101 -38.092 -4.987 1.00 134.66 ? 261 LEU G O 1 ATOM 2188 C CB . LEU B 2 119 ? -72.304 -38.703 -2.653 1.00 62.75 ? 261 LEU G CB 1 ATOM 2189 C CG . LEU B 2 119 ? -71.345 -38.658 -1.471 1.00 62.75 ? 261 LEU G CG 1 ATOM 2190 C CD1 . LEU B 2 119 ? -71.785 -37.503 -0.562 1.00 62.75 ? 261 LEU G CD1 1 ATOM 2191 C CD2 . LEU B 2 119 ? -71.276 -39.988 -0.739 1.00 62.75 ? 261 LEU G CD2 1 ATOM 2192 N N . ALA B 2 120 ? -72.249 -38.647 -6.105 1.00 187.16 ? 262 ALA G N 1 ATOM 2193 C CA . ALA B 2 120 ? -73.080 -39.057 -7.258 1.00 187.16 ? 262 ALA G CA 1 ATOM 2194 C C . ALA B 2 120 ? -73.775 -40.347 -6.870 1.00 187.16 ? 262 ALA G C 1 ATOM 2195 O O . ALA B 2 120 ? -73.159 -41.286 -6.366 1.00 187.16 ? 262 ALA G O 1 ATOM 2196 C CB . ALA B 2 120 ? -72.244 -39.308 -8.520 1.00 62.45 ? 262 ALA G CB 1 ATOM 2197 N N . GLU B 2 121 ? -75.091 -40.322 -7.040 1.00 114.04 ? 263 GLU G N 1 ATOM 2198 C CA . GLU B 2 121 ? -75.978 -41.417 -6.717 1.00 114.04 ? 263 GLU G CA 1 ATOM 2199 C C . GLU B 2 121 ? -75.955 -42.841 -7.306 1.00 114.04 ? 263 GLU G C 1 ATOM 2200 O O . GLU B 2 121 ? -76.036 -43.792 -6.531 1.00 114.04 ? 263 GLU G O 1 ATOM 2201 C CB . GLU B 2 121 ? -77.363 -40.789 -6.931 1.00 127.92 ? 263 GLU G CB 1 ATOM 2202 C CG . GLU B 2 121 ? -77.607 -40.541 -8.453 1.00 127.92 ? 263 GLU G CG 1 ATOM 2203 C CD . GLU B 2 121 ? -78.966 -39.904 -8.880 1.00 127.92 ? 263 GLU G CD 1 ATOM 2204 O OE1 . GLU B 2 121 ? -79.067 -39.539 -10.062 1.00 127.92 ? 263 GLU G OE1 1 ATOM 2205 O OE2 . GLU B 2 121 ? -79.918 -39.732 -8.092 1.00 127.92 ? 263 GLU G OE2 1 ATOM 2206 N N . GLU B 2 122 ? -75.720 -43.041 -8.602 1.00 126.67 ? 264 GLU G N 1 ATOM 2207 C CA . GLU B 2 122 ? -75.799 -44.443 -9.008 1.00 126.67 ? 264 GLU G CA 1 ATOM 2208 C C . GLU B 2 122 ? -74.520 -45.039 -9.593 1.00 126.67 ? 264 GLU G C 1 ATOM 2209 O O . GLU B 2 122 ? -74.141 -46.194 -9.349 1.00 126.67 ? 264 GLU G O 1 ATOM 2210 C CB . GLU B 2 122 ? -76.905 -44.549 -10.080 1.00 128.35 ? 264 GLU G CB 1 ATOM 2211 C CG . GLU B 2 122 ? -78.335 -44.283 -9.585 1.00 128.35 ? 264 GLU G CG 1 ATOM 2212 C CD . GLU B 2 122 ? -79.402 -44.399 -10.681 1.00 128.35 ? 264 GLU G CD 1 ATOM 2213 O OE1 . GLU B 2 122 ? -79.044 -44.521 -11.876 1.00 128.35 ? 264 GLU G OE1 1 ATOM 2214 O OE2 . GLU B 2 122 ? -80.609 -44.271 -10.359 1.00 128.35 ? 264 GLU G OE2 1 ATOM 2215 N N . GLU B 2 123 ? -73.792 -44.137 -10.229 1.00 140.92 ? 265 GLU G N 1 ATOM 2216 C CA . GLU B 2 123 ? -72.587 -44.389 -11.010 1.00 140.92 ? 265 GLU G CA 1 ATOM 2217 C C . GLU B 2 123 ? -71.532 -43.361 -10.695 1.00 140.92 ? 265 GLU G C 1 ATOM 2218 O O . GLU B 2 123 ? -71.850 -42.265 -10.216 1.00 140.92 ? 265 GLU G O 1 ATOM 2219 C CB . GLU B 2 123 ? -72.899 -44.510 -12.528 1.00 145.37 ? 265 GLU G CB 1 ATOM 2220 C CG . GLU B 2 123 ? -73.684 -45.815 -12.887 1.00 145.37 ? 265 GLU G CG 1 ATOM 2221 C CD . GLU B 2 123 ? -72.849 -47.129 -12.729 1.00 145.37 ? 265 GLU G CD 1 ATOM 2222 O OE1 . GLU B 2 123 ? -71.805 -47.261 -13.412 1.00 145.37 ? 265 GLU G OE1 1 ATOM 2223 O OE2 . GLU B 2 123 ? -73.206 -48.013 -11.897 1.00 145.37 ? 265 GLU G OE2 1 ATOM 2224 N N . VAL B 2 124 ? -70.283 -43.691 -11.003 1.00 130.64 ? 266 VAL G N 1 ATOM 2225 C CA . VAL B 2 124 ? -69.156 -42.833 -10.665 1.00 130.64 ? 266 VAL G CA 1 ATOM 2226 C C . VAL B 2 124 ? -68.759 -42.356 -12.049 1.00 130.64 ? 266 VAL G C 1 ATOM 2227 O O . VAL B 2 124 ? -68.328 -43.078 -12.941 1.00 130.64 ? 266 VAL G O 1 ATOM 2228 C CB . VAL B 2 124 ? -67.998 -43.637 -10.002 1.00 79.79 ? 266 VAL G CB 1 ATOM 2229 C CG1 . VAL B 2 124 ? -66.851 -42.714 -9.668 1.00 79.79 ? 266 VAL G CG1 1 ATOM 2230 C CG2 . VAL B 2 124 ? -68.505 -44.282 -8.689 1.00 79.79 ? 266 VAL G CG2 1 ATOM 2231 N N . VAL B 2 125 ? -68.837 -41.032 -12.063 1.00 160.97 ? 267 VAL G N 1 ATOM 2232 C CA . VAL B 2 125 ? -68.808 -40.075 -13.155 1.00 160.97 ? 267 VAL G CA 1 ATOM 2233 C C . VAL B 2 125 ? -67.558 -39.224 -13.230 1.00 160.97 ? 267 VAL G C 1 ATOM 2234 O O . VAL B 2 125 ? -67.130 -38.655 -12.231 1.00 160.97 ? 267 VAL G O 1 ATOM 2235 C CB . VAL B 2 125 ? -70.027 -39.091 -13.057 1.00 182.76 ? 267 VAL G CB 1 ATOM 2236 C CG1 . VAL B 2 125 ? -69.991 -38.089 -14.206 1.00 182.76 ? 267 VAL G CG1 1 ATOM 2237 C CG2 . VAL B 2 125 ? -71.335 -39.859 -13.027 1.00 182.76 ? 267 VAL G CG2 1 ATOM 2238 N N . ILE B 2 126 ? -66.961 -39.166 -14.416 1.00 167.20 ? 268 ILE G N 1 ATOM 2239 C CA . ILE B 2 126 ? -65.731 -38.422 -14.634 1.00 167.20 ? 268 ILE G CA 1 ATOM 2240 C C . ILE B 2 126 ? -65.981 -37.332 -15.678 1.00 167.20 ? 268 ILE G C 1 ATOM 2241 O O . ILE B 2 126 ? -66.369 -37.598 -16.806 1.00 167.20 ? 268 ILE G O 1 ATOM 2242 C CB . ILE B 2 126 ? -64.664 -39.378 -15.175 1.00 101.01 ? 268 ILE G CB 1 ATOM 2243 C CG1 . ILE B 2 126 ? -64.406 -40.503 -14.173 1.00 101.01 ? 268 ILE G CG1 1 ATOM 2244 C CG2 . ILE B 2 126 ? -63.455 -38.633 -15.621 1.00 101.01 ? 268 ILE G CG2 1 ATOM 2245 C CD1 . ILE B 2 126 ? -63.539 -41.638 -14.715 1.00 101.01 ? 268 ILE G CD1 1 ATOM 2246 N N . ARG B 2 127 ? -65.756 -36.083 -15.246 1.00 144.41 ? 269 ARG G N 1 ATOM 2247 C CA . ARG B 2 127 ? -66.065 -34.915 -16.069 1.00 144.41 ? 269 ARG G CA 1 ATOM 2248 C C . ARG B 2 127 ? -64.822 -34.064 -16.362 1.00 144.41 ? 269 ARG G C 1 ATOM 2249 O O . ARG B 2 127 ? -64.078 -33.716 -15.451 1.00 144.41 ? 269 ARG G O 1 ATOM 2250 C CB . ARG B 2 127 ? -67.045 -34.113 -15.212 1.00 152.76 ? 269 ARG G CB 1 ATOM 2251 C CG . ARG B 2 127 ? -68.334 -34.905 -14.987 1.00 152.76 ? 269 ARG G CG 1 ATOM 2252 C CD . ARG B 2 127 ? -69.400 -34.210 -14.143 1.00 152.76 ? 269 ARG G CD 1 ATOM 2253 N NE . ARG B 2 127 ? -70.464 -35.177 -13.853 1.00 152.76 ? 269 ARG G NE 1 ATOM 2254 C CZ . ARG B 2 127 ? -70.897 -35.475 -12.624 1.00 152.76 ? 269 ARG G CZ 1 ATOM 2255 N NH1 . ARG B 2 127 ? -70.381 -34.881 -11.563 1.00 152.76 ? 269 ARG G NH1 1 ATOM 2256 N NH2 . ARG B 2 127 ? -71.799 -36.423 -12.434 1.00 152.76 ? 269 ARG G NH2 1 ATOM 2257 N N . SER B 2 128 ? -64.627 -33.732 -17.635 1.00 101.02 ? 270 SER G N 1 ATOM 2258 C CA . SER B 2 128 ? -63.540 -32.880 -18.135 1.00 101.02 ? 270 SER G CA 1 ATOM 2259 C C . SER B 2 128 ? -63.953 -31.927 -19.209 1.00 101.02 ? 270 SER G C 1 ATOM 2260 O O . SER B 2 128 ? -64.912 -32.220 -19.876 1.00 101.02 ? 270 SER G O 1 ATOM 2261 C CB . SER B 2 128 ? -62.363 -33.696 -18.615 1.00 86.83 ? 270 SER G CB 1 ATOM 2262 O OG . SER B 2 128 ? -61.833 -34.459 -17.542 1.00 86.83 ? 270 SER G OG 1 ATOM 2263 N N . GLU B 2 129 ? -63.301 -30.782 -19.386 1.00 146.77 ? 271 GLU G N 1 ATOM 2264 C CA . GLU B 2 129 ? -63.745 -29.963 -20.498 1.00 146.77 ? 271 GLU G CA 1 ATOM 2265 C C . GLU B 2 129 ? -63.489 -30.967 -21.684 1.00 146.77 ? 271 GLU G C 1 ATOM 2266 O O . GLU B 2 129 ? -64.285 -30.983 -22.617 1.00 146.77 ? 271 GLU G O 1 ATOM 2267 C CB . GLU B 2 129 ? -63.037 -28.580 -20.576 1.00 123.35 ? 271 GLU G CB 1 ATOM 2268 C CG . GLU B 2 129 ? -63.524 -27.709 -21.774 1.00 123.35 ? 271 GLU G CG 1 ATOM 2269 C CD . GLU B 2 129 ? -62.855 -26.319 -21.904 1.00 123.35 ? 271 GLU G CD 1 ATOM 2270 O OE1 . GLU B 2 129 ? -62.133 -25.913 -20.965 1.00 123.35 ? 271 GLU G OE1 1 ATOM 2271 O OE2 . GLU B 2 129 ? -63.068 -25.621 -22.941 1.00 123.35 ? 271 GLU G OE2 1 ATOM 2272 N N . ASN B 2 130 ? -62.376 -31.737 -21.689 1.00 81.16 ? 272 ASN G N 1 ATOM 2273 C CA . ASN B 2 130 ? -62.125 -32.846 -22.677 1.00 81.16 ? 272 ASN G CA 1 ATOM 2274 C C . ASN B 2 130 ? -61.589 -33.985 -21.691 1.00 81.16 ? 272 ASN G C 1 ATOM 2275 O O . ASN B 2 130 ? -60.695 -33.696 -20.926 1.00 81.16 ? 272 ASN G O 1 ATOM 2276 C CB . ASN B 2 130 ? -61.081 -32.371 -23.878 1.00 125.11 ? 272 ASN G CB 1 ATOM 2277 C CG . ASN B 2 130 ? -60.803 -33.501 -25.103 1.00 125.11 ? 272 ASN G CG 1 ATOM 2278 O OD1 . ASN B 2 130 ? -61.022 -34.650 -24.780 1.00 125.11 ? 272 ASN G OD1 1 ATOM 2279 N ND2 . ASN B 2 130 ? -60.490 -33.237 -26.436 1.00 125.11 ? 272 ASN G ND2 1 ATOM 2280 N N . ILE B 2 131 ? -62.206 -35.178 -21.552 1.00 114.88 ? 273 ILE G N 1 ATOM 2281 C CA . ILE B 2 131 ? -61.586 -36.323 -20.776 1.00 114.88 ? 273 ILE G CA 1 ATOM 2282 C C . ILE B 2 131 ? -60.364 -36.950 -21.463 1.00 114.88 ? 273 ILE G C 1 ATOM 2283 O O . ILE B 2 131 ? -59.374 -37.336 -20.833 1.00 114.88 ? 273 ILE G O 1 ATOM 2284 C CB . ILE B 2 131 ? -62.524 -37.535 -20.529 1.00 134.47 ? 273 ILE G CB 1 ATOM 2285 C CG1 . ILE B 2 131 ? -63.758 -37.116 -19.734 1.00 134.47 ? 273 ILE G CG1 1 ATOM 2286 C CG2 . ILE B 2 131 ? -61.732 -38.679 -19.812 1.00 134.47 ? 273 ILE G CG2 1 ATOM 2287 C CD1 . ILE B 2 131 ? -63.439 -36.549 -18.403 1.00 134.47 ? 273 ILE G CD1 1 ATOM 2288 N N . SER B 2 132 ? -60.507 -37.068 -22.779 1.00 137.69 ? 274 SER G N 1 ATOM 2289 C CA . SER B 2 132 ? -59.526 -37.652 -23.674 1.00 137.69 ? 274 SER G CA 1 ATOM 2290 C C . SER B 2 132 ? -58.405 -36.667 -23.689 1.00 137.69 ? 274 SER G C 1 ATOM 2291 O O . SER B 2 132 ? -57.251 -37.011 -24.033 1.00 137.69 ? 274 SER G O 1 ATOM 2292 C CB . SER B 2 132 ? -60.069 -37.882 -25.098 1.00 113.57 ? 274 SER G CB 1 ATOM 2293 O OG . SER B 2 132 ? -60.294 -36.681 -25.827 1.00 113.57 ? 274 SER G OG 1 ATOM 2294 N N . ASN B 2 133 ? -58.721 -35.428 -23.294 1.00 285.47 ? 275 ASN G N 1 ATOM 2295 C CA . ASN B 2 133 ? -57.649 -34.478 -23.326 1.00 285.47 ? 275 ASN G CA 1 ATOM 2296 C C . ASN B 2 133 ? -56.714 -34.876 -22.258 1.00 285.47 ? 275 ASN G C 1 ATOM 2297 O O . ASN B 2 133 ? -56.939 -34.950 -21.034 1.00 285.47 ? 275 ASN G O 1 ATOM 2298 C CB . ASN B 2 133 ? -58.030 -33.011 -23.092 1.00 141.76 ? 275 ASN G CB 1 ATOM 2299 C CG . ASN B 2 133 ? -56.843 -32.061 -23.344 1.00 141.76 ? 275 ASN G CG 1 ATOM 2300 O OD1 . ASN B 2 133 ? -56.244 -32.060 -24.428 1.00 141.76 ? 275 ASN G OD1 1 ATOM 2301 N ND2 . ASN B 2 133 ? -56.504 -31.260 -22.337 1.00 141.76 ? 275 ASN G ND2 1 ATOM 2302 N N . ASN B 2 134 ? -55.589 -35.024 -22.895 1.00 150.81 ? 276 ASN G N 1 ATOM 2303 C CA . ASN B 2 134 ? -54.344 -35.424 -22.426 1.00 150.81 ? 276 ASN G CA 1 ATOM 2304 C C . ASN B 2 134 ? -53.880 -34.424 -21.339 1.00 150.81 ? 276 ASN G C 1 ATOM 2305 O O . ASN B 2 134 ? -53.240 -34.819 -20.373 1.00 150.81 ? 276 ASN G O 1 ATOM 2306 C CB . ASN B 2 134 ? -53.732 -35.367 -23.823 1.00 199.19 ? 276 ASN G CB 1 ATOM 2307 C CG . ASN B 2 134 ? -54.100 -34.021 -24.537 1.00 199.19 ? 276 ASN G CG 1 ATOM 2308 O OD1 . ASN B 2 134 ? -53.782 -32.956 -24.037 1.00 199.19 ? 276 ASN G OD1 1 ATOM 2309 N ND2 . ASN B 2 134 ? -54.870 -34.092 -25.646 1.00 199.19 ? 276 ASN G ND2 1 ATOM 2310 N N . VAL B 2 135 ? -54.122 -33.134 -21.548 1.00 81.67 ? 277 VAL G N 1 ATOM 2311 C CA . VAL B 2 135 ? -53.978 -32.015 -20.599 1.00 81.67 ? 277 VAL G CA 1 ATOM 2312 C C . VAL B 2 135 ? -54.832 -31.695 -19.350 1.00 81.67 ? 277 VAL G C 1 ATOM 2313 O O . VAL B 2 135 ? -54.292 -31.372 -18.322 1.00 81.67 ? 277 VAL G O 1 ATOM 2314 C CB . VAL B 2 135 ? -53.849 -30.721 -21.395 1.00 115.50 ? 277 VAL G CB 1 ATOM 2315 C CG1 . VAL B 2 135 ? -53.944 -29.504 -20.481 1.00 115.50 ? 277 VAL G CG1 1 ATOM 2316 C CG2 . VAL B 2 135 ? -52.590 -30.778 -22.232 1.00 115.50 ? 277 VAL G CG2 1 ATOM 2317 N N . LYS B 2 136 ? -56.167 -31.845 -19.481 1.00 74.14 ? 278 LYS G N 1 ATOM 2318 C CA . LYS B 2 136 ? -57.239 -31.457 -18.494 1.00 74.14 ? 278 LYS G CA 1 ATOM 2319 C C . LYS B 2 136 ? -57.531 -32.067 -17.164 1.00 74.14 ? 278 LYS G C 1 ATOM 2320 O O . LYS B 2 136 ? -57.659 -33.266 -17.027 1.00 74.14 ? 278 LYS G O 1 ATOM 2321 C CB . LYS B 2 136 ? -58.597 -31.357 -19.176 1.00 77.14 ? 278 LYS G CB 1 ATOM 2322 C CG . LYS B 2 136 ? -58.766 -30.342 -20.297 1.00 77.14 ? 278 LYS G CG 1 ATOM 2323 C CD . LYS B 2 136 ? -58.748 -28.895 -19.796 1.00 77.14 ? 278 LYS G CD 1 ATOM 2324 C CE . LYS B 2 136 ? -58.920 -27.851 -20.933 1.00 77.14 ? 278 LYS G CE 1 ATOM 2325 N NZ . LYS B 2 136 ? -59.179 -26.445 -20.427 1.00 77.14 ? 278 LYS G NZ 1 ATOM 2326 N N . THR B 2 137 ? -57.845 -31.204 -16.220 1.00 95.73 ? 279 THR G N 1 ATOM 2327 C CA . THR B 2 137 ? -58.124 -31.621 -14.849 1.00 95.73 ? 279 THR G CA 1 ATOM 2328 C C . THR B 2 137 ? -59.312 -32.574 -14.882 1.00 95.73 ? 279 THR G C 1 ATOM 2329 O O . THR B 2 137 ? -60.239 -32.397 -15.616 1.00 95.73 ? 279 THR G O 1 ATOM 2330 C CB . THR B 2 137 ? -58.577 -30.391 -13.965 1.00 64.23 ? 279 THR G CB 1 ATOM 2331 O OG1 . THR B 2 137 ? -57.575 -29.389 -13.909 1.00 64.23 ? 279 THR G OG1 1 ATOM 2332 C CG2 . THR B 2 137 ? -58.903 -30.787 -12.616 1.00 64.23 ? 279 THR G CG2 1 ATOM 2333 N N . ILE B 2 138 ? -59.262 -33.614 -14.092 1.00 82.84 ? 280 ILE G N 1 ATOM 2334 C CA . ILE B 2 138 ? -60.372 -34.540 -14.019 1.00 82.84 ? 280 ILE G CA 1 ATOM 2335 C C . ILE B 2 138 ? -61.026 -34.705 -12.655 1.00 82.84 ? 280 ILE G C 1 ATOM 2336 O O . ILE B 2 138 ? -60.399 -35.158 -11.697 1.00 82.84 ? 280 ILE G O 1 ATOM 2337 C CB . ILE B 2 138 ? -60.052 -35.985 -14.582 1.00 46.39 ? 280 ILE G CB 1 ATOM 2338 C CG1 . ILE B 2 138 ? -59.642 -35.941 -16.062 1.00 46.39 ? 280 ILE G CG1 1 ATOM 2339 C CG2 . ILE B 2 138 ? -61.117 -36.986 -14.075 1.00 46.39 ? 280 ILE G CG2 1 ATOM 2340 C CD1 . ILE B 2 138 ? -59.112 -37.221 -16.566 1.00 46.39 ? 280 ILE G CD1 1 ATOM 2341 N N . ILE B 2 139 ? -62.327 -34.383 -12.621 1.00 120.68 ? 281 ILE G N 1 ATOM 2342 C CA . ILE B 2 139 ? -63.128 -34.366 -11.404 1.00 120.68 ? 281 ILE G CA 1 ATOM 2343 C C . ILE B 2 139 ? -63.471 -35.666 -10.689 1.00 120.68 ? 281 ILE G C 1 ATOM 2344 O O . ILE B 2 139 ? -63.496 -35.667 -9.475 1.00 120.68 ? 281 ILE G O 1 ATOM 2345 C CB . ILE B 2 139 ? -64.421 -33.546 -11.589 1.00 78.87 ? 281 ILE G CB 1 ATOM 2346 C CG1 . ILE B 2 139 ? -64.114 -32.095 -11.938 1.00 78.87 ? 281 ILE G CG1 1 ATOM 2347 C CG2 . ILE B 2 139 ? -65.168 -33.486 -10.274 1.00 78.87 ? 281 ILE G CG2 1 ATOM 2348 C CD1 . ILE B 2 139 ? -63.315 -31.397 -10.938 1.00 78.87 ? 281 ILE G CD1 1 ATOM 2349 N N . VAL B 2 140 ? -63.792 -36.747 -11.391 1.00 147.25 ? 282 VAL G N 1 ATOM 2350 C CA . VAL B 2 140 ? -64.090 -38.000 -10.690 1.00 147.25 ? 282 VAL G CA 1 ATOM 2351 C C . VAL B 2 140 ? -65.130 -37.848 -9.526 1.00 147.25 ? 282 VAL G C 1 ATOM 2352 O O . VAL B 2 140 ? -64.783 -37.994 -8.359 1.00 147.25 ? 282 VAL G O 1 ATOM 2353 C CB . VAL B 2 140 ? -62.760 -38.559 -10.117 1.00 111.67 ? 282 VAL G CB 1 ATOM 2354 C CG1 . VAL B 2 140 ? -62.920 -39.972 -9.616 1.00 111.67 ? 282 VAL G CG1 1 ATOM 2355 C CG2 . VAL B 2 140 ? -61.696 -38.478 -11.155 1.00 111.67 ? 282 VAL G CG2 1 ATOM 2356 N N . HIS B 2 141 ? -66.401 -37.594 -9.841 1.00 139.15 ? 283 HIS G N 1 ATOM 2357 C CA . HIS B 2 141 ? -67.467 -37.412 -8.837 1.00 139.15 ? 283 HIS G CA 1 ATOM 2358 C C . HIS B 2 141 ? -67.832 -38.827 -8.307 1.00 139.15 ? 283 HIS G C 1 ATOM 2359 O O . HIS B 2 141 ? -68.227 -39.693 -9.094 1.00 139.15 ? 283 HIS G O 1 ATOM 2360 C CB . HIS B 2 141 ? -68.614 -36.682 -9.566 1.00 155.26 ? 283 HIS G CB 1 ATOM 2361 C CG . HIS B 2 141 ? -69.817 -36.387 -8.729 1.00 155.26 ? 283 HIS G CG 1 ATOM 2362 N ND1 . HIS B 2 141 ? -69.735 -35.757 -7.505 1.00 155.26 ? 283 HIS G ND1 1 ATOM 2363 C CD2 . HIS B 2 141 ? -71.139 -36.484 -9.011 1.00 155.26 ? 283 HIS G CD2 1 ATOM 2364 C CE1 . HIS B 2 141 ? -70.951 -35.485 -7.066 1.00 155.26 ? 283 HIS G CE1 1 ATOM 2365 N NE2 . HIS B 2 141 ? -71.820 -35.915 -7.962 1.00 155.26 ? 283 HIS G NE2 1 ATOM 2366 N N . LEU B 2 142 ? -67.763 -39.045 -6.981 1.00 109.80 ? 284 LEU G N 1 ATOM 2367 C CA . LEU B 2 142 ? -67.958 -40.406 -6.413 1.00 109.80 ? 284 LEU G CA 1 ATOM 2368 C C . LEU B 2 142 ? -69.241 -40.975 -5.761 1.00 109.80 ? 284 LEU G C 1 ATOM 2369 O O . LEU B 2 142 ? -69.958 -40.278 -5.054 1.00 109.80 ? 284 LEU G O 1 ATOM 2370 C CB . LEU B 2 142 ? -66.856 -40.698 -5.377 1.00 83.37 ? 284 LEU G CB 1 ATOM 2371 C CG . LEU B 2 142 ? -65.361 -40.706 -5.710 1.00 83.37 ? 284 LEU G CG 1 ATOM 2372 C CD1 . LEU B 2 142 ? -64.567 -41.038 -4.423 1.00 83.37 ? 284 LEU G CD1 1 ATOM 2373 C CD2 . LEU B 2 142 ? -65.081 -41.697 -6.892 1.00 83.37 ? 284 LEU G CD2 1 ATOM 2374 N N . THR B 2 143 ? -69.552 -42.247 -6.083 1.00 138.92 ? 285 THR G N 1 ATOM 2375 C CA . THR B 2 143 ? -70.702 -42.964 -5.487 1.00 138.92 ? 285 THR G CA 1 ATOM 2376 C C . THR B 2 143 ? -70.695 -43.330 -4.019 1.00 138.92 ? 285 THR G C 1 ATOM 2377 O O . THR B 2 143 ? -71.684 -43.149 -3.324 1.00 138.92 ? 285 THR G O 1 ATOM 2378 C CB . THR B 2 143 ? -70.924 -44.363 -6.121 1.00 115.87 ? 285 THR G CB 1 ATOM 2379 O OG1 . THR B 2 143 ? -71.178 -44.248 -7.526 1.00 115.87 ? 285 THR G OG1 1 ATOM 2380 C CG2 . THR B 2 143 ? -72.073 -45.091 -5.397 1.00 115.87 ? 285 THR G CG2 1 ATOM 2381 N N . GLU B 2 144 ? -69.561 -43.787 -3.514 1.00 106.61 ? 286 GLU G N 1 ATOM 2382 C CA . GLU B 2 144 ? -69.604 -44.168 -2.116 1.00 106.61 ? 286 GLU G CA 1 ATOM 2383 C C . GLU B 2 144 ? -68.461 -43.406 -1.473 1.00 106.61 ? 286 GLU G C 1 ATOM 2384 O O . GLU B 2 144 ? -67.335 -43.412 -1.947 1.00 106.61 ? 286 GLU G O 1 ATOM 2385 C CB . GLU B 2 144 ? -69.493 -45.714 -2.058 1.00 150.61 ? 286 GLU G CB 1 ATOM 2386 C CG . GLU B 2 144 ? -69.510 -46.420 -0.689 1.00 150.61 ? 286 GLU G CG 1 ATOM 2387 C CD . GLU B 2 144 ? -69.389 -47.961 -0.815 1.00 150.61 ? 286 GLU G CD 1 ATOM 2388 O OE1 . GLU B 2 144 ? -69.229 -48.646 0.213 1.00 150.61 ? 286 GLU G OE1 1 ATOM 2389 O OE2 . GLU B 2 144 ? -69.423 -48.494 -1.947 1.00 150.61 ? 286 GLU G OE2 1 ATOM 2390 N N . SER B 2 145 ? -68.785 -42.740 -0.389 1.00 145.64 ? 287 SER G N 1 ATOM 2391 C CA . SER B 2 145 ? -67.855 -41.920 0.357 1.00 145.64 ? 287 SER G CA 1 ATOM 2392 C C . SER B 2 145 ? -66.894 -42.482 1.420 1.00 145.64 ? 287 SER G C 1 ATOM 2393 O O . SER B 2 145 ? -67.104 -43.589 1.905 1.00 145.64 ? 287 SER G O 1 ATOM 2394 C CB . SER B 2 145 ? -68.653 -40.696 0.792 1.00 116.71 ? 287 SER G CB 1 ATOM 2395 O OG . SER B 2 145 ? -69.811 -41.063 1.493 1.00 116.71 ? 287 SER G OG 1 ATOM 2396 N N . VAL B 2 146 ? -65.824 -41.747 1.756 1.00 120.90 ? 288 VAL G N 1 ATOM 2397 C CA . VAL B 2 146 ? -64.841 -42.203 2.784 1.00 120.90 ? 288 VAL G CA 1 ATOM 2398 C C . VAL B 2 146 ? -64.524 -41.160 3.861 1.00 120.90 ? 288 VAL G C 1 ATOM 2399 O O . VAL B 2 146 ? -64.637 -39.956 3.625 1.00 120.90 ? 288 VAL G O 1 ATOM 2400 C CB . VAL B 2 146 ? -63.501 -42.603 2.147 1.00 105.13 ? 288 VAL G CB 1 ATOM 2401 C CG1 . VAL B 2 146 ? -63.722 -43.754 1.147 1.00 105.13 ? 288 VAL G CG1 1 ATOM 2402 C CG2 . VAL B 2 146 ? -62.894 -41.381 1.440 1.00 105.13 ? 288 VAL G CG2 1 ATOM 2403 N N . ASN B 2 147 ? -64.004 -41.623 4.991 1.00 149.98 ? 289 ASN G N 1 ATOM 2404 C CA . ASN B 2 147 ? -63.761 -40.729 6.112 1.00 149.98 ? 289 ASN G CA 1 ATOM 2405 C C . ASN B 2 147 ? -62.276 -40.447 6.387 1.00 149.98 ? 289 ASN G C 1 ATOM 2406 O O . ASN B 2 147 ? -61.450 -41.372 6.441 1.00 149.98 ? 289 ASN G O 1 ATOM 2407 C CB . ASN B 2 147 ? -64.355 -41.313 7.432 1.00 140.60 ? 289 ASN G CB 1 ATOM 2408 C CG . ASN B 2 147 ? -65.914 -41.328 7.500 1.00 140.60 ? 289 ASN G CG 1 ATOM 2409 O OD1 . ASN B 2 147 ? -66.593 -40.609 6.780 1.00 140.60 ? 289 ASN G OD1 1 ATOM 2410 N ND2 . ASN B 2 147 ? -66.466 -42.158 8.406 1.00 140.60 ? 289 ASN G ND2 1 ATOM 2411 N N . ILE B 2 148 ? -61.957 -39.154 6.511 1.00 99.82 ? 290 ILE G N 1 ATOM 2412 C CA . ILE B 2 148 ? -60.638 -38.667 6.914 1.00 99.82 ? 290 ILE G CA 1 ATOM 2413 C C . ILE B 2 148 ? -60.665 -37.855 8.154 1.00 99.82 ? 290 ILE G C 1 ATOM 2414 O O . ILE B 2 148 ? -61.370 -36.855 8.249 1.00 99.82 ? 290 ILE G O 1 ATOM 2415 C CB . ILE B 2 148 ? -59.827 -37.817 5.907 1.00 73.30 ? 290 ILE G CB 1 ATOM 2416 C CG1 . ILE B 2 148 ? -59.544 -38.578 4.632 1.00 73.30 ? 290 ILE G CG1 1 ATOM 2417 C CG2 . ILE B 2 148 ? -58.649 -37.219 6.569 1.00 73.30 ? 290 ILE G CG2 1 ATOM 2418 C CD1 . ILE B 2 148 ? -58.873 -37.706 3.578 1.00 73.30 ? 290 ILE G CD1 1 ATOM 2419 N N . THR B 2 149 ? -59.921 -38.367 9.132 1.00 116.50 ? 291 THR G N 1 ATOM 2420 C CA . THR B 2 149 ? -59.747 -37.764 10.447 1.00 116.50 ? 291 THR G CA 1 ATOM 2421 C C . THR B 2 149 ? -58.257 -37.475 10.653 1.00 116.50 ? 291 THR G C 1 ATOM 2422 O O . THR B 2 149 ? -57.438 -38.346 10.336 1.00 116.50 ? 291 THR G O 1 ATOM 2423 C CB . THR B 2 149 ? -60.316 -38.671 11.572 1.00 111.29 ? 291 THR G CB 1 ATOM 2424 O OG1 . THR B 2 149 ? -61.728 -38.881 11.353 1.00 111.29 ? 291 THR G OG1 1 ATOM 2425 C CG2 . THR B 2 149 ? -60.133 -37.996 12.922 1.00 111.29 ? 291 THR G CG2 1 ATOM 2426 N N . CYS B 2 150 ? -57.906 -36.247 11.065 1.00 101.69 ? 292 CYS G N 1 ATOM 2427 C CA . CYS B 2 150 ? -56.505 -35.891 11.304 1.00 101.69 ? 292 CYS G CA 1 ATOM 2428 C C . CYS B 2 150 ? -56.305 -35.235 12.668 1.00 101.69 ? 292 CYS G C 1 ATOM 2429 O O . CYS B 2 150 ? -57.236 -34.636 13.219 1.00 101.69 ? 292 CYS G O 1 ATOM 2430 C CB . CYS B 2 150 ? -55.980 -34.841 10.311 1.00 148.98 ? 292 CYS G CB 1 ATOM 2431 S SG . CYS B 2 150 ? -55.938 -35.107 8.514 1.00 148.98 ? 292 CYS G SG 1 ATOM 2432 N N . ILE B 2 151 ? -55.110 -35.439 13.235 1.00 200.27 ? 293 ILE G N 1 ATOM 2433 C CA . ILE B 2 151 ? -54.662 -34.752 14.451 1.00 200.27 ? 293 ILE G CA 1 ATOM 2434 C C . ILE B 2 151 ? -53.182 -34.341 14.268 1.00 200.27 ? 293 ILE G C 1 ATOM 2435 O O . ILE B 2 151 ? -52.387 -35.098 13.709 1.00 200.27 ? 293 ILE G O 1 ATOM 2436 C CB . ILE B 2 151 ? -54.850 -35.583 15.767 1.00 175.41 ? 293 ILE G CB 1 ATOM 2437 C CG1 . ILE B 2 151 ? -54.504 -37.060 15.548 1.00 175.41 ? 293 ILE G CG1 1 ATOM 2438 C CG2 . ILE B 2 151 ? -56.270 -35.359 16.313 1.00 175.41 ? 293 ILE G CG2 1 ATOM 2439 C CD1 . ILE B 2 151 ? -55.664 -37.922 15.113 1.00 175.41 ? 293 ILE G CD1 1 ATOM 2440 N N . GLY B 2 152 ? -52.811 -33.150 14.726 1.00 98.75 ? 294 GLY G N 1 ATOM 2441 C CA . GLY B 2 152 ? -51.427 -32.712 14.604 1.00 98.75 ? 294 GLY G CA 1 ATOM 2442 C C . GLY B 2 152 ? -50.730 -32.669 15.950 1.00 98.75 ? 294 GLY G C 1 ATOM 2443 O O . GLY B 2 152 ? -50.518 -33.699 16.587 1.00 98.75 ? 294 GLY G O 1 ATOM 2444 N N . GLY B 2 154 ? -49.077 -34.030 13.685 1.00 107.82 ? 324 GLY G N 1 ATOM 2445 C CA . GLY B 2 154 ? -49.260 -35.434 14.006 1.00 107.82 ? 324 GLY G CA 1 ATOM 2446 C C . GLY B 2 154 ? -49.529 -36.367 12.828 1.00 107.82 ? 324 GLY G C 1 ATOM 2447 O O . GLY B 2 154 ? -48.715 -36.517 11.925 1.00 107.82 ? 324 GLY G O 1 ATOM 2448 N N . HIS B 2 155 ? -50.681 -37.017 12.832 1.00 163.58 ? 325 HIS G N 1 ATOM 2449 C CA . HIS B 2 155 ? -50.992 -37.931 11.755 1.00 163.58 ? 325 HIS G CA 1 ATOM 2450 C C . HIS B 2 155 ? -52.418 -37.896 11.275 1.00 163.58 ? 325 HIS G C 1 ATOM 2451 O O . HIS B 2 155 ? -53.311 -37.421 11.981 1.00 163.58 ? 325 HIS G O 1 ATOM 2452 C CB . HIS B 2 155 ? -50.644 -39.359 12.196 1.00 160.53 ? 325 HIS G CB 1 ATOM 2453 C CG . HIS B 2 155 ? -51.394 -39.838 13.420 1.00 160.53 ? 325 HIS G CG 1 ATOM 2454 N ND1 . HIS B 2 155 ? -51.018 -39.502 14.708 1.00 160.53 ? 325 HIS G ND1 1 ATOM 2455 C CD2 . HIS B 2 155 ? -52.458 -40.669 13.554 1.00 160.53 ? 325 HIS G CD2 1 ATOM 2456 C CE1 . HIS B 2 155 ? -51.807 -40.111 15.577 1.00 160.53 ? 325 HIS G CE1 1 ATOM 2457 N NE2 . HIS B 2 155 ? -52.690 -40.825 14.903 1.00 160.53 ? 325 HIS G NE2 1 ATOM 2458 N N . CYS B 2 156 ? -52.627 -38.394 10.058 1.00 167.73 ? 326 CYS G N 1 ATOM 2459 C CA . CYS B 2 156 ? -53.978 -38.494 9.519 1.00 167.73 ? 326 CYS G CA 1 ATOM 2460 C C . CYS B 2 156 ? -54.389 -39.929 9.177 1.00 167.73 ? 326 CYS G C 1 ATOM 2461 O O . CYS B 2 156 ? -53.593 -40.695 8.603 1.00 167.73 ? 326 CYS G O 1 ATOM 2462 C CB . CYS B 2 156 ? -54.189 -37.594 8.303 1.00 149.83 ? 326 CYS G CB 1 ATOM 2463 S SG . CYS B 2 156 ? -55.941 -37.109 8.285 1.00 149.83 ? 326 CYS G SG 1 ATOM 2464 N N . ASN B 2 157 ? -55.647 -40.266 9.504 1.00 113.39 ? 327 ASN G N 1 ATOM 2465 C CA . ASN B 2 157 ? -56.164 -41.599 9.264 1.00 113.39 ? 327 ASN G CA 1 ATOM 2466 C C . ASN B 2 157 ? -57.227 -41.733 8.158 1.00 113.39 ? 327 ASN G C 1 ATOM 2467 O O . ASN B 2 157 ? -58.268 -41.079 8.179 1.00 113.39 ? 327 ASN G O 1 ATOM 2468 C CB . ASN B 2 157 ? -56.729 -42.174 10.571 1.00 164.59 ? 327 ASN G CB 1 ATOM 2469 C CG . ASN B 2 157 ? -55.649 -42.504 11.595 1.00 164.59 ? 327 ASN G CG 1 ATOM 2470 O OD1 . ASN B 2 157 ? -54.481 -42.664 11.252 1.00 164.59 ? 327 ASN G OD1 1 ATOM 2471 N ND2 . ASN B 2 157 ? -56.044 -42.616 12.862 1.00 164.59 ? 327 ASN G ND2 1 ATOM 2472 N N . ILE B 2 158 ? -56.878 -42.551 7.164 1.00 154.17 ? 328 ILE G N 1 ATOM 2473 C CA . ILE B 2 158 ? -57.716 -42.969 6.042 1.00 154.17 ? 328 ILE G CA 1 ATOM 2474 C C . ILE B 2 158 ? -57.769 -44.470 6.193 1.00 154.17 ? 328 ILE G C 1 ATOM 2475 O O . ILE B 2 158 ? -56.732 -45.141 6.332 1.00 154.17 ? 328 ILE G O 1 ATOM 2476 C CB . ILE B 2 158 ? -57.181 -42.582 4.607 1.00 105.66 ? 328 ILE G CB 1 ATOM 2477 C CG1 . ILE B 2 158 ? -57.037 -41.068 4.457 1.00 105.66 ? 328 ILE G CG1 1 ATOM 2478 C CG2 . ILE B 2 158 ? -58.018 -43.223 3.534 1.00 105.66 ? 328 ILE G CG2 1 ATOM 2479 C CD1 . ILE B 2 158 ? -56.307 -40.645 3.191 1.00 105.66 ? 328 ILE G CD1 1 ATOM 2480 N N . ASN B 2 159 ? -58.976 -45.004 6.154 1.00 159.33 ? 329 ASN G N 1 ATOM 2481 C CA . ASN B 2 159 ? -59.152 -46.428 6.347 1.00 159.33 ? 329 ASN G CA 1 ATOM 2482 C C . ASN B 2 159 ? -58.452 -47.272 5.290 1.00 159.33 ? 329 ASN G C 1 ATOM 2483 O O . ASN B 2 159 ? -58.530 -47.011 4.100 1.00 159.33 ? 329 ASN G O 1 ATOM 2484 C CB . ASN B 2 159 ? -60.636 -46.735 6.344 1.00 117.36 ? 329 ASN G CB 1 ATOM 2485 C CG . ASN B 2 159 ? -60.918 -48.170 6.623 1.00 117.36 ? 329 ASN G CG 1 ATOM 2486 O OD1 . ASN B 2 159 ? -60.307 -48.772 7.519 1.00 117.36 ? 329 ASN G OD1 1 ATOM 2487 N ND2 . ASN B 2 159 ? -61.855 -48.746 5.861 1.00 117.36 ? 329 ASN G ND2 1 ATOM 2488 N N . GLU B 2 160 ? -57.698 -48.247 5.767 1.00 180.54 ? 330 GLU G N 1 ATOM 2489 C CA . GLU B 2 160 ? -56.946 -49.153 4.913 1.00 180.54 ? 330 GLU G CA 1 ATOM 2490 C C . GLU B 2 160 ? -57.931 -49.898 4.007 1.00 180.54 ? 330 GLU G C 1 ATOM 2491 O O . GLU B 2 160 ? -57.741 -50.052 2.794 1.00 180.54 ? 330 GLU G O 1 ATOM 2492 C CB . GLU B 2 160 ? -56.467 -50.228 5.847 1.00 106.90 ? 330 GLU G CB 1 ATOM 2493 C CG . GLU B 2 160 ? -55.429 -49.896 6.840 1.00 106.90 ? 330 GLU G CG 1 ATOM 2494 C CD . GLU B 2 160 ? -55.167 -51.102 7.711 1.00 106.90 ? 330 GLU G CD 1 ATOM 2495 O OE1 . GLU B 2 160 ? -55.898 -51.304 8.730 1.00 106.90 ? 330 GLU G OE1 1 ATOM 2496 O OE2 . GLU B 2 160 ? -54.253 -51.859 7.333 1.00 106.90 ? 330 GLU G OE2 1 ATOM 2497 N N . LYS B 2 161 ? -59.044 -50.247 4.661 1.00 151.27 ? 331 LYS G N 1 ATOM 2498 C CA . LYS B 2 161 ? -60.125 -51.075 4.132 1.00 151.27 ? 331 LYS G CA 1 ATOM 2499 C C . LYS B 2 161 ? -60.917 -50.489 3.002 1.00 151.27 ? 331 LYS G C 1 ATOM 2500 O O . LYS B 2 161 ? -61.263 -51.192 2.051 1.00 151.27 ? 331 LYS G O 1 ATOM 2501 C CB . LYS B 2 161 ? -61.053 -51.388 5.299 1.00 109.32 ? 331 LYS G CB 1 ATOM 2502 C CG . LYS B 2 161 ? -60.379 -52.337 6.335 1.00 109.32 ? 331 LYS G CG 1 ATOM 2503 C CD . LYS B 2 161 ? -61.260 -52.706 7.556 1.00 109.32 ? 331 LYS G CD 1 ATOM 2504 C CE . LYS B 2 161 ? -60.470 -53.638 8.511 1.00 109.32 ? 331 LYS G CE 1 ATOM 2505 N NZ . LYS B 2 161 ? -61.146 -53.832 9.786 1.00 109.32 ? 331 LYS G NZ 1 ATOM 2506 N N . ALA B 2 162 ? -61.186 -49.190 3.116 1.00 110.93 ? 332 ALA G N 1 ATOM 2507 C CA . ALA B 2 162 ? -61.937 -48.482 2.082 1.00 110.93 ? 332 ALA G CA 1 ATOM 2508 C C . ALA B 2 162 ? -61.270 -48.506 0.689 1.00 110.93 ? 332 ALA G C 1 ATOM 2509 O O . ALA B 2 162 ? -61.979 -48.548 -0.324 1.00 110.93 ? 332 ALA G O 1 ATOM 2510 C CB . ALA B 2 162 ? -62.217 -47.028 2.526 1.00 80.55 ? 332 ALA G CB 1 ATOM 2511 N N . TRP B 2 163 ? -59.931 -48.360 0.650 1.00 99.25 ? 333 TRP G N 1 ATOM 2512 C CA . TRP B 2 163 ? -59.157 -48.420 -0.600 1.00 99.25 ? 333 TRP G CA 1 ATOM 2513 C C . TRP B 2 163 ? -59.172 -49.683 -1.478 1.00 99.25 ? 333 TRP G C 1 ATOM 2514 O O . TRP B 2 163 ? -59.210 -49.562 -2.705 1.00 99.25 ? 333 TRP G O 1 ATOM 2515 C CB . TRP B 2 163 ? -57.701 -48.033 -0.337 1.00 134.28 ? 333 TRP G CB 1 ATOM 2516 C CG . TRP B 2 163 ? -57.537 -46.549 -0.259 1.00 134.28 ? 333 TRP G CG 1 ATOM 2517 C CD1 . TRP B 2 163 ? -57.596 -45.784 0.878 1.00 134.28 ? 333 TRP G CD1 1 ATOM 2518 C CD2 . TRP B 2 163 ? -57.381 -45.634 -1.341 1.00 134.28 ? 333 TRP G CD2 1 ATOM 2519 N NE1 . TRP B 2 163 ? -57.497 -44.451 0.571 1.00 134.28 ? 333 TRP G NE1 1 ATOM 2520 C CE2 . TRP B 2 163 ? -57.365 -44.330 -0.786 1.00 134.28 ? 333 TRP G CE2 1 ATOM 2521 C CE3 . TRP B 2 163 ? -57.257 -45.782 -2.727 1.00 134.28 ? 333 TRP G CE3 1 ATOM 2522 C CZ2 . TRP B 2 163 ? -57.234 -43.187 -1.570 1.00 134.28 ? 333 TRP G CZ2 1 ATOM 2523 C CZ3 . TRP B 2 163 ? -57.123 -44.640 -3.507 1.00 134.28 ? 333 TRP G CZ3 1 ATOM 2524 C CH2 . TRP B 2 163 ? -57.113 -43.359 -2.922 1.00 134.28 ? 333 TRP G CH2 1 ATOM 2525 N N . ASN B 2 164 ? -59.141 -50.891 -0.897 1.00 246.63 ? 334 ASN G N 1 ATOM 2526 C CA . ASN B 2 164 ? -59.214 -52.046 -1.789 1.00 246.63 ? 334 ASN G CA 1 ATOM 2527 C C . ASN B 2 164 ? -60.567 -52.182 -2.534 1.00 246.63 ? 334 ASN G C 1 ATOM 2528 O O . ASN B 2 164 ? -60.564 -52.535 -3.716 1.00 246.63 ? 334 ASN G O 1 ATOM 2529 C CB . ASN B 2 164 ? -58.805 -53.360 -1.078 1.00 112.45 ? 334 ASN G CB 1 ATOM 2530 C CG . ASN B 2 164 ? -57.320 -53.427 -0.756 1.00 112.45 ? 334 ASN G CG 1 ATOM 2531 O OD1 . ASN B 2 164 ? -56.507 -52.777 -1.400 1.00 112.45 ? 334 ASN G OD1 1 ATOM 2532 N ND2 . ASN B 2 164 ? -56.962 -54.241 0.224 1.00 112.45 ? 334 ASN G ND2 1 ATOM 2533 N N . GLU B 2 165 ? -61.713 -51.918 -1.879 1.00 198.61 ? 335 GLU G N 1 ATOM 2534 C CA . GLU B 2 165 ? -63.008 -51.895 -2.601 1.00 198.61 ? 335 GLU G CA 1 ATOM 2535 C C . GLU B 2 165 ? -63.102 -50.821 -3.666 1.00 198.61 ? 335 GLU G C 1 ATOM 2536 O O . GLU B 2 165 ? -63.642 -51.028 -4.760 1.00 198.61 ? 335 GLU G O 1 ATOM 2537 C CB . GLU B 2 165 ? -64.230 -51.692 -1.689 1.00 157.86 ? 335 GLU G CB 1 ATOM 2538 C CG . GLU B 2 165 ? -64.650 -52.796 -0.752 1.00 157.86 ? 335 GLU G CG 1 ATOM 2539 C CD . GLU B 2 165 ? -63.751 -53.028 0.428 1.00 157.86 ? 335 GLU G CD 1 ATOM 2540 O OE1 . GLU B 2 165 ? -63.948 -54.047 1.128 1.00 157.86 ? 335 GLU G OE1 1 ATOM 2541 O OE2 . GLU B 2 165 ? -62.829 -52.233 0.646 1.00 157.86 ? 335 GLU G OE2 1 ATOM 2542 N N . THR B 2 166 ? -62.559 -49.661 -3.319 1.00 132.18 ? 336 THR G N 1 ATOM 2543 C CA . THR B 2 166 ? -62.587 -48.520 -4.205 1.00 132.18 ? 336 THR G CA 1 ATOM 2544 C C . THR B 2 166 ? -61.661 -48.814 -5.373 1.00 132.18 ? 336 THR G C 1 ATOM 2545 O O . THR B 2 166 ? -61.822 -48.228 -6.444 1.00 132.18 ? 336 THR G O 1 ATOM 2546 C CB . THR B 2 166 ? -62.157 -47.243 -3.433 1.00 70.18 ? 336 THR G CB 1 ATOM 2547 O OG1 . THR B 2 166 ? -60.842 -47.467 -2.910 1.00 70.18 ? 336 THR G OG1 1 ATOM 2548 C CG2 . THR B 2 166 ? -63.130 -46.886 -2.286 1.00 70.18 ? 336 THR G CG2 1 ATOM 2549 N N . LEU B 2 167 ? -60.659 -49.675 -5.146 1.00 142.64 ? 337 LEU G N 1 ATOM 2550 C CA . LEU B 2 167 ? -59.756 -50.048 -6.231 1.00 142.64 ? 337 LEU G CA 1 ATOM 2551 C C . LEU B 2 167 ? -60.620 -50.683 -7.296 1.00 142.64 ? 337 LEU G C 1 ATOM 2552 O O . LEU B 2 167 ? -60.420 -50.464 -8.475 1.00 142.64 ? 337 LEU G O 1 ATOM 2553 C CB . LEU B 2 167 ? -58.737 -51.127 -5.799 1.00 141.57 ? 337 LEU G CB 1 ATOM 2554 C CG . LEU B 2 167 ? -57.620 -50.950 -4.752 1.00 141.57 ? 337 LEU G CG 1 ATOM 2555 C CD1 . LEU B 2 167 ? -56.885 -52.280 -4.559 1.00 141.57 ? 337 LEU G CD1 1 ATOM 2556 C CD2 . LEU B 2 167 ? -56.657 -49.857 -5.161 1.00 141.57 ? 337 LEU G CD2 1 ATOM 2557 N N . LYS B 2 168 ? -61.585 -51.481 -6.842 1.00 234.54 ? 338 LYS G N 1 ATOM 2558 C CA . LYS B 2 168 ? -62.503 -52.195 -7.720 1.00 234.54 ? 338 LYS G CA 1 ATOM 2559 C C . LYS B 2 168 ? -63.431 -51.418 -8.636 1.00 234.54 ? 338 LYS G C 1 ATOM 2560 O O . LYS B 2 168 ? -63.660 -51.807 -9.788 1.00 234.54 ? 338 LYS G O 1 ATOM 2561 C CB . LYS B 2 168 ? -63.393 -53.099 -6.857 1.00 107.99 ? 338 LYS G CB 1 ATOM 2562 C CG . LYS B 2 168 ? -62.718 -54.309 -6.201 1.00 107.99 ? 338 LYS G CG 1 ATOM 2563 C CD . LYS B 2 168 ? -63.715 -55.090 -5.309 1.00 107.99 ? 338 LYS G CD 1 ATOM 2564 C CE . LYS B 2 168 ? -64.864 -55.755 -6.080 1.00 107.99 ? 338 LYS G CE 1 ATOM 2565 N NZ . LYS B 2 168 ? -65.795 -54.773 -6.719 1.00 107.99 ? 338 LYS G NZ 1 ATOM 2566 N N . LYS B 2 169 ? -63.978 -50.323 -8.113 1.00 191.65 ? 339 LYS G N 1 ATOM 2567 C CA . LYS B 2 169 ? -64.939 -49.542 -8.885 1.00 191.65 ? 339 LYS G CA 1 ATOM 2568 C C . LYS B 2 169 ? -64.203 -48.842 -10.034 1.00 191.65 ? 339 LYS G C 1 ATOM 2569 O O . LYS B 2 169 ? -64.682 -48.741 -11.170 1.00 191.65 ? 339 LYS G O 1 ATOM 2570 C CB . LYS B 2 169 ? -65.608 -48.530 -7.944 1.00 98.65 ? 339 LYS G CB 1 ATOM 2571 C CG . LYS B 2 169 ? -66.316 -49.271 -6.831 1.00 98.65 ? 339 LYS G CG 1 ATOM 2572 C CD . LYS B 2 169 ? -67.531 -50.034 -7.249 1.00 98.65 ? 339 LYS G CD 1 ATOM 2573 C CE . LYS B 2 169 ? -68.122 -50.721 -6.015 1.00 98.65 ? 339 LYS G CE 1 ATOM 2574 N NZ . LYS B 2 169 ? -69.391 -51.439 -6.288 1.00 98.65 ? 339 LYS G NZ 1 ATOM 2575 N N . VAL B 2 170 ? -63.012 -48.367 -9.673 1.00 170.36 ? 340 VAL G N 1 ATOM 2576 C CA . VAL B 2 170 ? -62.089 -47.664 -10.555 1.00 170.36 ? 340 VAL G CA 1 ATOM 2577 C C . VAL B 2 170 ? -61.533 -48.628 -11.561 1.00 170.36 ? 340 VAL G C 1 ATOM 2578 O O . VAL B 2 170 ? -61.385 -48.287 -12.732 1.00 170.36 ? 340 VAL G O 1 ATOM 2579 C CB . VAL B 2 170 ? -60.894 -47.053 -9.805 1.00 132.03 ? 340 VAL G CB 1 ATOM 2580 C CG1 . VAL B 2 170 ? -61.394 -46.343 -8.543 1.00 132.03 ? 340 VAL G CG1 1 ATOM 2581 C CG2 . VAL B 2 170 ? -59.837 -48.113 -9.522 1.00 132.03 ? 340 VAL G CG2 1 ATOM 2582 N N . VAL B 2 171 ? -61.228 -49.849 -11.107 1.00 221.96 ? 341 VAL G N 1 ATOM 2583 C CA . VAL B 2 171 ? -60.620 -50.771 -12.041 1.00 221.96 ? 341 VAL G CA 1 ATOM 2584 C C . VAL B 2 171 ? -61.782 -51.054 -12.968 1.00 221.96 ? 341 VAL G C 1 ATOM 2585 O O . VAL B 2 171 ? -61.586 -51.213 -14.175 1.00 221.96 ? 341 VAL G O 1 ATOM 2586 C CB . VAL B 2 171 ? -60.157 -52.146 -11.349 1.00 99.52 ? 341 VAL G CB 1 ATOM 2587 C CG1 . VAL B 2 171 ? -59.144 -51.894 -10.261 1.00 99.52 ? 341 VAL G CG1 1 ATOM 2588 C CG2 . VAL B 2 171 ? -61.338 -52.895 -10.752 1.00 99.52 ? 341 VAL G CG2 1 ATOM 2589 N N . GLU B 2 172 ? -62.981 -51.196 -12.410 1.00 218.29 ? 342 GLU G N 1 ATOM 2590 C CA . GLU B 2 172 ? -64.126 -51.383 -13.262 1.00 218.29 ? 342 GLU G CA 1 ATOM 2591 C C . GLU B 2 172 ? -64.370 -50.207 -14.252 1.00 218.29 ? 342 GLU G C 1 ATOM 2592 O O . GLU B 2 172 ? -64.615 -50.433 -15.439 1.00 218.29 ? 342 GLU G O 1 ATOM 2593 C CB . GLU B 2 172 ? -65.338 -51.773 -12.384 1.00 130.74 ? 342 GLU G CB 1 ATOM 2594 C CG . GLU B 2 172 ? -66.663 -52.050 -13.098 1.00 130.74 ? 342 GLU G CG 1 ATOM 2595 C CD . GLU B 2 172 ? -67.762 -52.437 -12.122 1.00 130.74 ? 342 GLU G CD 1 ATOM 2596 O OE1 . GLU B 2 172 ? -67.504 -52.478 -10.899 1.00 130.74 ? 342 GLU G OE1 1 ATOM 2597 O OE2 . GLU B 2 172 ? -68.848 -52.826 -12.591 1.00 130.74 ? 342 GLU G OE2 1 ATOM 2598 N N . LYS B 2 173 ? -64.355 -48.956 -13.746 1.00 117.08 ? 343 LYS G N 1 ATOM 2599 C CA . LYS B 2 173 ? -64.590 -47.761 -14.611 1.00 117.08 ? 343 LYS G CA 1 ATOM 2600 C C . LYS B 2 173 ? -63.675 -47.170 -15.700 1.00 117.08 ? 343 LYS G C 1 ATOM 2601 O O . LYS B 2 173 ? -64.096 -46.893 -16.838 1.00 117.08 ? 343 LYS G O 1 ATOM 2602 C CB . LYS B 2 173 ? -64.736 -46.528 -13.709 1.00 110.40 ? 343 LYS G CB 1 ATOM 2603 C CG . LYS B 2 173 ? -65.827 -46.447 -12.679 1.00 110.40 ? 343 LYS G CG 1 ATOM 2604 C CD . LYS B 2 173 ? -67.199 -46.295 -13.286 1.00 110.40 ? 343 LYS G CD 1 ATOM 2605 C CE . LYS B 2 173 ? -68.153 -45.980 -12.170 1.00 110.40 ? 343 LYS G CE 1 ATOM 2606 N NZ . LYS B 2 173 ? -67.799 -46.704 -10.914 1.00 110.40 ? 343 LYS G NZ 1 ATOM 2607 N N . LEU B 2 174 ? -62.392 -47.171 -15.384 1.00 138.21 ? 344 LEU G N 1 ATOM 2608 C CA . LEU B 2 174 ? -61.428 -46.514 -16.235 1.00 138.21 ? 344 LEU G CA 1 ATOM 2609 C C . LEU B 2 174 ? -61.184 -47.163 -17.551 1.00 138.21 ? 344 LEU G C 1 ATOM 2610 O O . LEU B 2 174 ? -61.114 -46.529 -18.613 1.00 138.21 ? 344 LEU G O 1 ATOM 2611 C CB . LEU B 2 174 ? -60.136 -46.275 -15.433 1.00 153.47 ? 344 LEU G CB 1 ATOM 2612 C CG . LEU B 2 174 ? -60.407 -45.380 -14.199 1.00 153.47 ? 344 LEU G CG 1 ATOM 2613 C CD1 . LEU B 2 174 ? -59.102 -45.181 -13.446 1.00 153.47 ? 344 LEU G CD1 1 ATOM 2614 C CD2 . LEU B 2 174 ? -61.032 -44.032 -14.613 1.00 153.47 ? 344 LEU G CD2 1 ATOM 2615 N N . VAL B 2 175 ? -61.149 -48.476 -17.443 1.00 190.81 ? 345 VAL G N 1 ATOM 2616 C CA . VAL B 2 175 ? -60.865 -49.336 -18.542 1.00 190.81 ? 345 VAL G CA 1 ATOM 2617 C C . VAL B 2 175 ? -61.941 -49.056 -19.559 1.00 190.81 ? 345 VAL G C 1 ATOM 2618 O O . VAL B 2 175 ? -61.668 -49.026 -20.754 1.00 190.81 ? 345 VAL G O 1 ATOM 2619 C CB . VAL B 2 175 ? -60.934 -50.810 -18.084 1.00 91.77 ? 345 VAL G CB 1 ATOM 2620 C CG1 . VAL B 2 175 ? -60.872 -51.761 -19.325 1.00 91.77 ? 345 VAL G CG1 1 ATOM 2621 C CG2 . VAL B 2 175 ? -59.834 -51.083 -16.986 1.00 91.77 ? 345 VAL G CG2 1 ATOM 2622 N N . LYS B 2 176 ? -63.172 -48.872 -19.087 1.00 226.33 ? 346 LYS G N 1 ATOM 2623 C CA . LYS B 2 176 ? -64.264 -48.649 -20.017 1.00 226.33 ? 346 LYS G CA 1 ATOM 2624 C C . LYS B 2 176 ? -63.977 -47.356 -20.868 1.00 226.33 ? 346 LYS G C 1 ATOM 2625 O O . LYS B 2 176 ? -64.195 -47.370 -22.090 1.00 226.33 ? 346 LYS G O 1 ATOM 2626 C CB . LYS B 2 176 ? -65.555 -48.746 -19.142 1.00 115.40 ? 346 LYS G CB 1 ATOM 2627 C CG . LYS B 2 176 ? -66.945 -48.677 -19.745 1.00 115.40 ? 346 LYS G CG 1 ATOM 2628 C CD . LYS B 2 176 ? -67.944 -48.806 -18.591 1.00 115.40 ? 346 LYS G CD 1 ATOM 2629 C CE . LYS B 2 176 ? -69.371 -48.798 -19.078 1.00 115.40 ? 346 LYS G CE 1 ATOM 2630 N NZ . LYS B 2 176 ? -69.575 -49.970 -19.990 1.00 115.40 ? 346 LYS G NZ 1 ATOM 2631 N N . TYR B 2 177 ? -63.442 -46.273 -20.274 1.00 106.62 ? 347 TYR G N 1 ATOM 2632 C CA . TYR B 2 177 ? -62.959 -45.129 -21.098 1.00 106.62 ? 347 TYR G CA 1 ATOM 2633 C C . TYR B 2 177 ? -61.693 -45.449 -21.904 1.00 106.62 ? 347 TYR G C 1 ATOM 2634 O O . TYR B 2 177 ? -61.540 -45.056 -23.075 1.00 106.62 ? 347 TYR G O 1 ATOM 2635 C CB . TYR B 2 177 ? -62.810 -43.707 -20.444 1.00 139.05 ? 347 TYR G CB 1 ATOM 2636 C CG . TYR B 2 177 ? -64.083 -42.910 -20.044 1.00 139.05 ? 347 TYR G CG 1 ATOM 2637 C CD1 . TYR B 2 177 ? -64.693 -43.005 -18.773 1.00 139.05 ? 347 TYR G CD1 1 ATOM 2638 C CD2 . TYR B 2 177 ? -64.708 -42.082 -21.006 1.00 139.05 ? 347 TYR G CD2 1 ATOM 2639 C CE1 . TYR B 2 177 ? -65.893 -42.268 -18.474 1.00 139.05 ? 347 TYR G CE1 1 ATOM 2640 C CE2 . TYR B 2 177 ? -65.897 -41.370 -20.727 1.00 139.05 ? 347 TYR G CE2 1 ATOM 2641 C CZ . TYR B 2 177 ? -66.483 -41.456 -19.465 1.00 139.05 ? 347 TYR G CZ 1 ATOM 2642 O OH . TYR B 2 177 ? -67.630 -40.712 -19.206 1.00 139.05 ? 347 TYR G OH 1 ATOM 2643 N N . PHE B 2 178 ? -60.798 -46.202 -21.256 1.00 175.28 ? 348 PHE G N 1 ATOM 2644 C CA . PHE B 2 178 ? -59.473 -46.552 -21.803 1.00 175.28 ? 348 PHE G CA 1 ATOM 2645 C C . PHE B 2 178 ? -59.268 -48.071 -21.677 1.00 175.28 ? 348 PHE G C 1 ATOM 2646 O O . PHE B 2 178 ? -58.603 -48.564 -20.759 1.00 175.28 ? 348 PHE G O 1 ATOM 2647 C CB . PHE B 2 178 ? -58.348 -45.906 -20.977 1.00 126.33 ? 348 PHE G CB 1 ATOM 2648 C CG . PHE B 2 178 ? -58.393 -44.413 -20.929 1.00 126.33 ? 348 PHE G CG 1 ATOM 2649 C CD1 . PHE B 2 178 ? -58.759 -43.673 -22.053 1.00 126.33 ? 348 PHE G CD1 1 ATOM 2650 C CD2 . PHE B 2 178 ? -58.046 -43.747 -19.748 1.00 126.33 ? 348 PHE G CD2 1 ATOM 2651 C CE1 . PHE B 2 178 ? -58.779 -42.295 -22.000 1.00 126.33 ? 348 PHE G CE1 1 ATOM 2652 C CE2 . PHE B 2 178 ? -58.060 -42.369 -19.680 1.00 126.33 ? 348 PHE G CE2 1 ATOM 2653 C CZ . PHE B 2 178 ? -58.426 -41.635 -20.803 1.00 126.33 ? 348 PHE G CZ 1 ATOM 2654 N N . PRO B 2 179 ? -59.865 -48.827 -22.618 1.00 170.51 ? 349 PRO G N 1 ATOM 2655 C CA . PRO B 2 179 ? -59.850 -50.290 -22.742 1.00 170.51 ? 349 PRO G CA 1 ATOM 2656 C C . PRO B 2 179 ? -58.480 -50.875 -23.040 1.00 170.51 ? 349 PRO G C 1 ATOM 2657 O O . PRO B 2 179 ? -57.630 -50.188 -23.608 1.00 170.51 ? 349 PRO G O 1 ATOM 2658 C CB . PRO B 2 179 ? -60.808 -50.550 -23.911 1.00 206.13 ? 349 PRO G CB 1 ATOM 2659 C CG . PRO B 2 179 ? -61.569 -49.234 -24.104 1.00 206.13 ? 349 PRO G CG 1 ATOM 2660 C CD . PRO B 2 179 ? -60.536 -48.217 -23.783 1.00 206.13 ? 349 PRO G CD 1 ATOM 2661 N N . ASN B 2 180 ? -58.266 -52.134 -22.653 1.00 196.62 ? 350 ASN G N 1 ATOM 2662 C CA . ASN B 2 180 ? -57.000 -52.795 -22.968 1.00 196.62 ? 350 ASN G CA 1 ATOM 2663 C C . ASN B 2 180 ? -55.837 -51.979 -22.386 1.00 196.62 ? 350 ASN G C 1 ATOM 2664 O O . ASN B 2 180 ? -54.820 -51.778 -23.045 1.00 196.62 ? 350 ASN G O 1 ATOM 2665 C CB . ASN B 2 180 ? -56.855 -52.909 -24.498 1.00 137.89 ? 350 ASN G CB 1 ATOM 2666 C CG . ASN B 2 180 ? -57.834 -53.914 -25.121 1.00 137.89 ? 350 ASN G CG 1 ATOM 2667 O OD1 . ASN B 2 180 ? -58.366 -54.811 -24.442 1.00 137.89 ? 350 ASN G OD1 1 ATOM 2668 N ND2 . ASN B 2 180 ? -58.070 -53.761 -26.428 1.00 137.89 ? 350 ASN G ND2 1 ATOM 2669 N N . LYS B 2 181 ? -56.032 -51.457 -21.181 1.00 140.62 ? 351 LYS G N 1 ATOM 2670 C CA . LYS B 2 181 ? -55.067 -50.574 -20.502 1.00 140.62 ? 351 LYS G CA 1 ATOM 2671 C C . LYS B 2 181 ? -54.690 -50.884 -19.006 1.00 140.62 ? 351 LYS G C 1 ATOM 2672 O O . LYS B 2 181 ? -55.427 -51.558 -18.296 1.00 140.62 ? 351 LYS G O 1 ATOM 2673 C CB . LYS B 2 181 ? -55.563 -49.152 -20.751 1.00 137.17 ? 351 LYS G CB 1 ATOM 2674 C CG . LYS B 2 181 ? -55.555 -48.863 -22.271 1.00 137.17 ? 351 LYS G CG 1 ATOM 2675 C CD . LYS B 2 181 ? -56.030 -47.474 -22.639 1.00 137.17 ? 351 LYS G CD 1 ATOM 2676 C CE . LYS B 2 181 ? -55.997 -47.246 -24.139 1.00 137.17 ? 351 LYS G CE 1 ATOM 2677 N NZ . LYS B 2 181 ? -56.894 -46.101 -24.457 1.00 137.17 ? 351 LYS G NZ 1 ATOM 2678 N N . THR B 2 182 ? -53.559 -50.370 -18.526 1.00 145.69 ? 352 THR G N 1 ATOM 2679 C CA . THR B 2 182 ? -53.026 -50.653 -17.163 1.00 145.69 ? 352 THR G CA 1 ATOM 2680 C C . THR B 2 182 ? -52.909 -49.347 -16.367 1.00 145.69 ? 352 THR G C 1 ATOM 2681 O O . THR B 2 182 ? -52.333 -48.364 -16.832 1.00 145.69 ? 352 THR G O 1 ATOM 2682 C CB . THR B 2 182 ? -51.572 -51.255 -17.177 1.00 122.75 ? 352 THR G CB 1 ATOM 2683 O OG1 . THR B 2 182 ? -51.538 -52.496 -17.901 1.00 122.75 ? 352 THR G OG1 1 ATOM 2684 C CG2 . THR B 2 182 ? -51.091 -51.496 -15.749 1.00 122.75 ? 352 THR G CG2 1 ATOM 2685 N N . ILE B 2 183 ? -53.448 -49.353 -15.146 1.00 186.69 ? 353 ILE G N 1 ATOM 2686 C CA . ILE B 2 183 ? -53.536 -48.122 -14.352 1.00 186.69 ? 353 ILE G CA 1 ATOM 2687 C C . ILE B 2 183 ? -52.647 -47.931 -13.079 1.00 186.69 ? 353 ILE G C 1 ATOM 2688 O O . ILE B 2 183 ? -52.619 -48.773 -12.172 1.00 186.69 ? 353 ILE G O 1 ATOM 2689 C CB . ILE B 2 183 ? -55.019 -47.969 -13.890 1.00 140.28 ? 353 ILE G CB 1 ATOM 2690 C CG1 . ILE B 2 183 ? -55.963 -47.878 -15.085 1.00 140.28 ? 353 ILE G CG1 1 ATOM 2691 C CG2 . ILE B 2 183 ? -55.182 -46.720 -13.072 1.00 140.28 ? 353 ILE G CG2 1 ATOM 2692 C CD1 . ILE B 2 183 ? -55.620 -46.835 -16.073 1.00 140.28 ? 353 ILE G CD1 1 ATOM 2693 N N . GLU B 2 184 ? -51.982 -46.764 -13.042 1.00 98.47 ? 354 GLU G N 1 ATOM 2694 C CA . GLU B 2 184 ? -51.082 -46.254 -11.975 1.00 98.47 ? 354 GLU G CA 1 ATOM 2695 C C . GLU B 2 184 ? -51.579 -45.164 -11.008 1.00 98.47 ? 354 GLU G C 1 ATOM 2696 O O . GLU B 2 184 ? -52.123 -44.140 -11.434 1.00 98.47 ? 354 GLU G O 1 ATOM 2697 C CB . GLU B 2 184 ? -49.838 -45.620 -12.629 1.00 146.23 ? 354 GLU G CB 1 ATOM 2698 C CG . GLU B 2 184 ? -48.736 -46.398 -13.357 1.00 146.23 ? 354 GLU G CG 1 ATOM 2699 C CD . GLU B 2 184 ? -47.865 -47.245 -12.424 1.00 146.23 ? 354 GLU G CD 1 ATOM 2700 O OE1 . GLU B 2 184 ? -47.195 -48.201 -12.873 1.00 146.23 ? 354 GLU G OE1 1 ATOM 2701 O OE2 . GLU B 2 184 ? -47.779 -46.884 -11.230 1.00 146.23 ? 354 GLU G OE2 1 ATOM 2702 N N . PHE B 2 185 ? -51.390 -45.368 -9.712 1.00 140.10 ? 355 PHE G N 1 ATOM 2703 C CA . PHE B 2 185 ? -51.618 -44.251 -8.808 1.00 140.10 ? 355 PHE G CA 1 ATOM 2704 C C . PHE B 2 185 ? -50.189 -43.981 -8.454 1.00 140.10 ? 355 PHE G C 1 ATOM 2705 O O . PHE B 2 185 ? -49.450 -44.845 -7.944 1.00 140.10 ? 355 PHE G O 1 ATOM 2706 C CB . PHE B 2 185 ? -52.365 -44.569 -7.503 1.00 148.36 ? 355 PHE G CB 1 ATOM 2707 C CG . PHE B 2 185 ? -53.822 -44.905 -7.657 1.00 148.36 ? 355 PHE G CG 1 ATOM 2708 C CD1 . PHE B 2 185 ? -54.468 -45.678 -6.675 1.00 148.36 ? 355 PHE G CD1 1 ATOM 2709 C CD2 . PHE B 2 185 ? -54.590 -44.294 -8.660 1.00 148.36 ? 355 PHE G CD2 1 ATOM 2710 C CE1 . PHE B 2 185 ? -55.832 -45.825 -6.683 1.00 148.36 ? 355 PHE G CE1 1 ATOM 2711 C CE2 . PHE B 2 185 ? -55.959 -44.438 -8.671 1.00 148.36 ? 355 PHE G CE2 1 ATOM 2712 C CZ . PHE B 2 185 ? -56.582 -45.201 -7.680 1.00 148.36 ? 355 PHE G CZ 1 ATOM 2713 N N . ALA B 2 186 ? -49.814 -42.747 -8.687 1.00 149.33 ? 356 ALA G N 1 ATOM 2714 C CA . ALA B 2 186 ? -48.471 -42.347 -8.418 1.00 149.33 ? 356 ALA G CA 1 ATOM 2715 C C . ALA B 2 186 ? -48.534 -40.967 -7.865 1.00 149.33 ? 356 ALA G C 1 ATOM 2716 O O . ALA B 2 186 ? -49.471 -40.225 -8.125 1.00 149.33 ? 356 ALA G O 1 ATOM 2717 C CB . ALA B 2 186 ? -47.645 -42.362 -9.704 1.00 107.42 ? 356 ALA G CB 1 ATOM 2718 N N . PRO B 2 187 ? -47.553 -40.616 -7.057 1.00 141.79 ? 357 PRO G N 1 ATOM 2719 C CA . PRO B 2 187 ? -47.447 -39.320 -6.452 1.00 141.79 ? 357 PRO G CA 1 ATOM 2720 C C . PRO B 2 187 ? -47.110 -38.309 -7.540 1.00 141.79 ? 357 PRO G C 1 ATOM 2721 O O . PRO B 2 187 ? -46.683 -38.692 -8.638 1.00 141.79 ? 357 PRO G O 1 ATOM 2722 C CB . PRO B 2 187 ? -46.354 -39.593 -5.469 1.00 145.51 ? 357 PRO G CB 1 ATOM 2723 C CG . PRO B 2 187 ? -45.321 -40.014 -6.436 1.00 145.51 ? 357 PRO G CG 1 ATOM 2724 C CD . PRO B 2 187 ? -46.187 -41.179 -7.097 1.00 145.51 ? 357 PRO G CD 1 ATOM 2725 N N . PRO B 2 188 ? -47.366 -37.021 -7.283 1.00 132.60 ? 358 PRO G N 1 ATOM 2726 C CA . PRO B 2 188 ? -47.083 -35.916 -8.220 1.00 132.60 ? 358 PRO G CA 1 ATOM 2727 C C . PRO B 2 188 ? -45.553 -35.655 -8.416 1.00 132.60 ? 358 PRO G C 1 ATOM 2728 O O . PRO B 2 188 ? -44.817 -35.400 -7.469 1.00 132.60 ? 358 PRO G O 1 ATOM 2729 C CB . PRO B 2 188 ? -47.833 -34.736 -7.590 1.00 99.01 ? 358 PRO G CB 1 ATOM 2730 C CG . PRO B 2 188 ? -47.913 -35.112 -6.101 1.00 99.01 ? 358 PRO G CG 1 ATOM 2731 C CD . PRO B 2 188 ? -48.182 -36.580 -6.141 1.00 99.01 ? 358 PRO G CD 1 ATOM 2732 N N . VAL B 2 189 ? -45.088 -35.681 -9.654 1.00 120.30 ? 359 VAL G N 1 ATOM 2733 C CA . VAL B 2 189 ? -43.664 -35.515 -9.987 1.00 120.30 ? 359 VAL G CA 1 ATOM 2734 C C . VAL B 2 189 ? -42.973 -34.222 -9.582 1.00 120.30 ? 359 VAL G C 1 ATOM 2735 O O . VAL B 2 189 ? -41.780 -34.220 -9.244 1.00 120.30 ? 359 VAL G O 1 ATOM 2736 C CB . VAL B 2 189 ? -43.382 -35.734 -11.490 1.00 62.76 ? 359 VAL G CB 1 ATOM 2737 C CG1 . VAL B 2 189 ? -43.972 -34.589 -12.309 1.00 62.76 ? 359 VAL G CG1 1 ATOM 2738 C CG2 . VAL B 2 189 ? -41.852 -36.002 -11.712 1.00 62.76 ? 359 VAL G CG2 1 ATOM 2739 N N . GLY B 2 190 ? -43.689 -33.119 -9.738 1.00 89.53 ? 360 GLY G N 1 ATOM 2740 C CA . GLY B 2 190 ? -43.128 -31.814 -9.449 1.00 89.53 ? 360 GLY G CA 1 ATOM 2741 C C . GLY B 2 190 ? -44.121 -30.844 -8.860 1.00 89.53 ? 360 GLY G C 1 ATOM 2742 O O . GLY B 2 190 ? -44.990 -31.239 -8.112 1.00 89.53 ? 360 GLY G O 1 ATOM 2743 N N . GLY B 2 191 ? -43.878 -29.559 -9.062 1.00 74.78 ? 361 GLY G N 1 ATOM 2744 C CA . GLY B 2 191 ? -44.791 -28.545 -8.589 1.00 74.78 ? 361 GLY G CA 1 ATOM 2745 C C . GLY B 2 191 ? -44.762 -28.110 -7.146 1.00 74.78 ? 361 GLY G C 1 ATOM 2746 O O . GLY B 2 191 ? -44.047 -28.662 -6.320 1.00 74.78 ? 361 GLY G O 1 ATOM 2747 N N . ASP B 2 192 ? -45.678 -27.211 -6.820 1.00 95.27 ? 362 ASP G N 1 ATOM 2748 C CA . ASP B 2 192 ? -45.756 -26.623 -5.500 1.00 95.27 ? 362 ASP G CA 1 ATOM 2749 C C . ASP B 2 192 ? -46.208 -27.553 -4.439 1.00 95.27 ? 362 ASP G C 1 ATOM 2750 O O . ASP B 2 192 ? -46.782 -28.612 -4.672 1.00 95.27 ? 362 ASP G O 1 ATOM 2751 C CB . ASP B 2 192 ? -46.680 -25.409 -5.452 1.00 113.78 ? 362 ASP G CB 1 ATOM 2752 C CG . ASP B 2 192 ? -46.130 -24.231 -6.172 1.00 113.78 ? 362 ASP G CG 1 ATOM 2753 O OD1 . ASP B 2 192 ? -44.906 -24.140 -6.229 1.00 113.78 ? 362 ASP G OD1 1 ATOM 2754 O OD2 . ASP B 2 192 ? -46.899 -23.391 -6.678 1.00 113.78 ? 362 ASP G OD2 1 ATOM 2755 N N . LEU B 2 193 ? -45.878 -27.155 -3.234 1.00 116.69 ? 363 LEU G N 1 ATOM 2756 C CA . LEU B 2 193 ? -46.200 -27.952 -2.094 1.00 116.69 ? 363 LEU G CA 1 ATOM 2757 C C . LEU B 2 193 ? -47.731 -28.146 -2.001 1.00 116.69 ? 363 LEU G C 1 ATOM 2758 O O . LEU B 2 193 ? -48.130 -29.271 -1.714 1.00 116.69 ? 363 LEU G O 1 ATOM 2759 C CB . LEU B 2 193 ? -45.632 -27.228 -0.869 1.00 117.37 ? 363 LEU G CB 1 ATOM 2760 C CG . LEU B 2 193 ? -45.746 -27.726 0.555 1.00 117.37 ? 363 LEU G CG 1 ATOM 2761 C CD1 . LEU B 2 193 ? -44.887 -28.968 0.719 1.00 117.37 ? 363 LEU G CD1 1 ATOM 2762 C CD2 . LEU B 2 193 ? -45.309 -26.638 1.457 1.00 117.37 ? 363 LEU G CD2 1 ATOM 2763 N N . GLU B 2 194 ? -48.576 -27.115 -2.246 1.00 101.41 ? 364 GLU G N 1 ATOM 2764 C CA . GLU B 2 194 ? -50.070 -27.297 -2.147 1.00 101.41 ? 364 GLU G CA 1 ATOM 2765 C C . GLU B 2 194 ? -50.684 -28.351 -3.092 1.00 101.41 ? 364 GLU G C 1 ATOM 2766 O O . GLU B 2 194 ? -51.659 -28.995 -2.739 1.00 101.41 ? 364 GLU G O 1 ATOM 2767 C CB . GLU B 2 194 ? -50.794 -25.991 -2.379 1.00 72.40 ? 364 GLU G CB 1 ATOM 2768 C CG . GLU B 2 194 ? -50.688 -24.899 -1.304 1.00 72.40 ? 364 GLU G CG 1 ATOM 2769 C CD . GLU B 2 194 ? -49.282 -24.177 -1.153 1.00 72.40 ? 364 GLU G CD 1 ATOM 2770 O OE1 . GLU B 2 194 ? -49.116 -23.407 -0.139 1.00 72.40 ? 364 GLU G OE1 1 ATOM 2771 O OE2 . GLU B 2 194 ? -48.336 -24.436 -1.972 1.00 72.40 ? 364 GLU G OE2 1 ATOM 2772 N N . ILE B 2 195 ? -50.193 -28.397 -4.328 1.00 84.19 ? 365 ILE G N 1 ATOM 2773 C CA . ILE B 2 195 ? -50.457 -29.398 -5.364 1.00 84.19 ? 365 ILE G CA 1 ATOM 2774 C C . ILE B 2 195 ? -49.842 -30.808 -5.093 1.00 84.19 ? 365 ILE G C 1 ATOM 2775 O O . ILE B 2 195 ? -50.459 -31.827 -5.305 1.00 84.19 ? 365 ILE G O 1 ATOM 2776 C CB . ILE B 2 195 ? -49.970 -28.793 -6.618 1.00 78.54 ? 365 ILE G CB 1 ATOM 2777 C CG1 . ILE B 2 195 ? -50.772 -27.524 -6.814 1.00 78.54 ? 365 ILE G CG1 1 ATOM 2778 C CG2 . ILE B 2 195 ? -49.878 -29.797 -7.724 1.00 78.54 ? 365 ILE G CG2 1 ATOM 2779 C CD1 . ILE B 2 195 ? -50.206 -26.700 -7.915 1.00 78.54 ? 365 ILE G CD1 1 ATOM 2780 N N . THR B 2 196 ? -48.617 -30.813 -4.569 1.00 67.12 ? 366 THR G N 1 ATOM 2781 C CA . THR B 2 196 ? -47.801 -31.967 -4.207 1.00 67.12 ? 366 THR G CA 1 ATOM 2782 C C . THR B 2 196 ? -48.462 -32.810 -3.188 1.00 67.12 ? 366 THR G C 1 ATOM 2783 O O . THR B 2 196 ? -48.377 -34.013 -3.196 1.00 67.12 ? 366 THR G O 1 ATOM 2784 C CB . THR B 2 196 ? -46.440 -31.529 -3.612 1.00 102.63 ? 366 THR G CB 1 ATOM 2785 O OG1 . THR B 2 196 ? -45.711 -30.745 -4.572 1.00 102.63 ? 366 THR G OG1 1 ATOM 2786 C CG2 . THR B 2 196 ? -45.634 -32.726 -3.121 1.00 102.63 ? 366 THR G CG2 1 ATOM 2787 N N . THR B 2 197 ? -49.075 -32.115 -2.265 1.00 84.49 ? 367 THR G N 1 ATOM 2788 C CA . THR B 2 197 ? -49.688 -32.686 -1.101 1.00 84.49 ? 367 THR G CA 1 ATOM 2789 C C . THR B 2 197 ? -51.097 -32.110 -1.095 1.00 84.49 ? 367 THR G C 1 ATOM 2790 O O . THR B 2 197 ? -51.470 -31.369 -1.973 1.00 84.49 ? 367 THR G O 1 ATOM 2791 C CB . THR B 2 197 ? -48.923 -32.278 0.226 1.00 75.43 ? 367 THR G CB 1 ATOM 2792 O OG1 . THR B 2 197 ? -49.096 -30.887 0.607 1.00 75.43 ? 367 THR G OG1 1 ATOM 2793 C CG2 . THR B 2 197 ? -47.430 -32.508 -0.065 1.00 75.43 ? 367 THR G CG2 1 ATOM 2794 N N . HIS B 2 198 ? -51.926 -32.645 -0.231 1.00 67.70 ? 368 HIS G N 1 ATOM 2795 C CA . HIS B 2 198 ? -53.256 -32.184 -0.065 1.00 67.70 ? 368 HIS G CA 1 ATOM 2796 C C . HIS B 2 198 ? -53.466 -30.958 0.763 1.00 67.70 ? 368 HIS G C 1 ATOM 2797 O O . HIS B 2 198 ? -53.652 -31.041 1.938 1.00 67.70 ? 368 HIS G O 1 ATOM 2798 C CB . HIS B 2 198 ? -53.964 -33.375 0.597 1.00 86.83 ? 368 HIS G CB 1 ATOM 2799 C CG . HIS B 2 198 ? -55.312 -33.076 1.186 1.00 86.83 ? 368 HIS G CG 1 ATOM 2800 N ND1 . HIS B 2 198 ? -56.328 -32.445 0.502 1.00 86.83 ? 368 HIS G ND1 1 ATOM 2801 C CD2 . HIS B 2 198 ? -55.806 -33.356 2.419 1.00 86.83 ? 368 HIS G CD2 1 ATOM 2802 C CE1 . HIS B 2 198 ? -57.384 -32.344 1.293 1.00 86.83 ? 368 HIS G CE1 1 ATOM 2803 N NE2 . HIS B 2 198 ? -57.094 -32.891 2.459 1.00 86.83 ? 368 HIS G NE2 1 ATOM 2804 N N . SER B 2 199 ? -53.574 -29.827 0.111 1.00 79.89 ? 369 SER G N 1 ATOM 2805 C CA . SER B 2 199 ? -53.910 -28.585 0.777 1.00 79.89 ? 369 SER G CA 1 ATOM 2806 C C . SER B 2 199 ? -55.348 -28.504 1.287 1.00 79.89 ? 369 SER G C 1 ATOM 2807 O O . SER B 2 199 ? -56.218 -28.850 0.511 1.00 79.89 ? 369 SER G O 1 ATOM 2808 C CB . SER B 2 199 ? -53.722 -27.399 -0.168 1.00 81.74 ? 369 SER G CB 1 ATOM 2809 O OG . SER B 2 199 ? -54.086 -26.145 0.476 1.00 81.74 ? 369 SER G OG 1 ATOM 2810 N N . PHE B 2 200 ? -55.628 -28.134 2.547 1.00 85.03 ? 370 PHE G N 1 ATOM 2811 C CA . PHE B 2 200 ? -57.047 -27.905 2.949 1.00 85.03 ? 370 PHE G CA 1 ATOM 2812 C C . PHE B 2 200 ? -57.184 -27.019 4.166 1.00 85.03 ? 370 PHE G C 1 ATOM 2813 O O . PHE B 2 200 ? -56.247 -26.904 4.913 1.00 85.03 ? 370 PHE G O 1 ATOM 2814 C CB . PHE B 2 200 ? -57.815 -29.181 3.214 1.00 83.39 ? 370 PHE G CB 1 ATOM 2815 C CG . PHE B 2 200 ? -57.393 -29.876 4.418 1.00 83.39 ? 370 PHE G CG 1 ATOM 2816 C CD1 . PHE B 2 200 ? -58.005 -29.580 5.619 1.00 83.39 ? 370 PHE G CD1 1 ATOM 2817 C CD2 . PHE B 2 200 ? -56.368 -30.802 4.368 1.00 83.39 ? 370 PHE G CD2 1 ATOM 2818 C CE1 . PHE B 2 200 ? -57.596 -30.198 6.765 1.00 83.39 ? 370 PHE G CE1 1 ATOM 2819 C CE2 . PHE B 2 200 ? -55.955 -31.423 5.501 1.00 83.39 ? 370 PHE G CE2 1 ATOM 2820 C CZ . PHE B 2 200 ? -56.562 -31.127 6.716 1.00 83.39 ? 370 PHE G CZ 1 ATOM 2821 N N . ASN B 2 201 ? -58.343 -26.414 4.392 1.00 134.77 ? 371 ASN G N 1 ATOM 2822 C CA . ASN B 2 201 ? -58.476 -25.528 5.538 1.00 134.77 ? 371 ASN G CA 1 ATOM 2823 C C . ASN B 2 201 ? -59.364 -26.035 6.681 1.00 134.77 ? 371 ASN G C 1 ATOM 2824 O O . ASN B 2 201 ? -60.575 -26.120 6.530 1.00 134.77 ? 371 ASN G O 1 ATOM 2825 C CB . ASN B 2 201 ? -58.996 -24.197 4.977 1.00 143.85 ? 371 ASN G CB 1 ATOM 2826 C CG . ASN B 2 201 ? -59.202 -23.139 6.017 1.00 143.85 ? 371 ASN G CG 1 ATOM 2827 O OD1 . ASN B 2 201 ? -60.298 -22.995 6.558 1.00 143.85 ? 371 ASN G OD1 1 ATOM 2828 N ND2 . ASN B 2 201 ? -58.163 -22.382 6.300 1.00 143.85 ? 371 ASN G ND2 1 ATOM 2829 N N . CYS B 2 202 ? -58.755 -26.379 7.825 1.00 112.65 ? 372 CYS G N 1 ATOM 2830 C CA . CYS B 2 202 ? -59.485 -26.783 9.052 1.00 112.65 ? 372 CYS G CA 1 ATOM 2831 C C . CYS B 2 202 ? -59.221 -25.937 10.315 1.00 112.65 ? 372 CYS G C 1 ATOM 2832 O O . CYS B 2 202 ? -58.201 -26.105 10.969 1.00 112.65 ? 372 CYS G O 1 ATOM 2833 C CB . CYS B 2 202 ? -59.182 -28.256 9.425 1.00 145.12 ? 372 CYS G CB 1 ATOM 2834 S SG . CYS B 2 202 ? -60.620 -29.141 10.102 1.00 145.12 ? 372 CYS G SG 1 ATOM 2835 N N . GLY B 2 203 ? -60.187 -25.135 10.744 1.00 151.44 ? 373 GLY G N 1 ATOM 2836 C CA . GLY B 2 203 ? -59.967 -24.382 11.966 1.00 151.44 ? 373 GLY G CA 1 ATOM 2837 C C . GLY B 2 203 ? -58.965 -23.242 11.986 1.00 151.44 ? 373 GLY G C 1 ATOM 2838 O O . GLY B 2 203 ? -58.534 -22.872 13.080 1.00 151.44 ? 373 GLY G O 1 ATOM 2839 N N . GLY B 2 204 ? -58.622 -22.647 10.841 1.00 106.31 ? 374 GLY G N 1 ATOM 2840 C CA . GLY B 2 204 ? -57.588 -21.605 10.843 1.00 106.31 ? 374 GLY G CA 1 ATOM 2841 C C . GLY B 2 204 ? -56.114 -22.080 10.872 1.00 106.31 ? 374 GLY G C 1 ATOM 2842 O O . GLY B 2 204 ? -55.207 -21.338 11.275 1.00 106.31 ? 374 GLY G O 1 ATOM 2843 N N . GLU B 2 205 ? -55.914 -23.350 10.500 1.00 123.04 ? 375 GLU G N 1 ATOM 2844 C CA . GLU B 2 205 ? -54.608 -24.012 10.396 1.00 123.04 ? 375 GLU G CA 1 ATOM 2845 C C . GLU B 2 205 ? -54.638 -24.470 8.902 1.00 123.04 ? 375 GLU G C 1 ATOM 2846 O O . GLU B 2 205 ? -55.719 -24.767 8.415 1.00 123.04 ? 375 GLU G O 1 ATOM 2847 C CB . GLU B 2 205 ? -54.555 -25.227 11.319 1.00 179.47 ? 375 GLU G CB 1 ATOM 2848 C CG . GLU B 2 205 ? -54.552 -24.900 12.810 1.00 179.47 ? 375 GLU G CG 1 ATOM 2849 C CD . GLU B 2 205 ? -53.280 -24.243 13.293 1.00 179.47 ? 375 GLU G CD 1 ATOM 2850 O OE1 . GLU B 2 205 ? -53.307 -23.649 14.393 1.00 179.47 ? 375 GLU G OE1 1 ATOM 2851 O OE2 . GLU B 2 205 ? -52.269 -24.286 12.566 1.00 179.47 ? 375 GLU G OE2 1 ATOM 2852 N N . PHE B 2 206 ? -53.515 -24.581 8.168 1.00 97.32 ? 376 PHE G N 1 ATOM 2853 C CA . PHE B 2 206 ? -53.646 -24.933 6.745 1.00 97.32 ? 376 PHE G CA 1 ATOM 2854 C C . PHE B 2 206 ? -52.836 -26.210 6.830 1.00 97.32 ? 376 PHE G C 1 ATOM 2855 O O . PHE B 2 206 ? -51.852 -26.237 7.489 1.00 97.32 ? 376 PHE G O 1 ATOM 2856 C CB . PHE B 2 206 ? -52.874 -23.939 5.892 1.00 94.64 ? 376 PHE G CB 1 ATOM 2857 C CG . PHE B 2 206 ? -53.489 -22.553 5.850 1.00 94.64 ? 376 PHE G CG 1 ATOM 2858 C CD1 . PHE B 2 206 ? -53.103 -21.621 6.801 1.00 94.64 ? 376 PHE G CD1 1 ATOM 2859 C CD2 . PHE B 2 206 ? -54.431 -22.163 4.923 1.00 94.64 ? 376 PHE G CD2 1 ATOM 2860 C CE1 . PHE B 2 206 ? -53.629 -20.312 6.840 1.00 94.64 ? 376 PHE G CE1 1 ATOM 2861 C CE2 . PHE B 2 206 ? -54.970 -20.851 4.953 1.00 94.64 ? 376 PHE G CE2 1 ATOM 2862 C CZ . PHE B 2 206 ? -54.558 -19.933 5.918 1.00 94.64 ? 376 PHE G CZ 1 ATOM 2863 N N . PHE B 2 207 ? -53.248 -27.255 6.151 1.00 115.00 ? 377 PHE G N 1 ATOM 2864 C CA . PHE B 2 207 ? -52.642 -28.603 6.199 1.00 115.00 ? 377 PHE G CA 1 ATOM 2865 C C . PHE B 2 207 ? -52.102 -29.160 4.881 1.00 115.00 ? 377 PHE G C 1 ATOM 2866 O O . PHE B 2 207 ? -52.658 -28.830 3.834 1.00 115.00 ? 377 PHE G O 1 ATOM 2867 C CB . PHE B 2 207 ? -53.691 -29.602 6.748 1.00 99.12 ? 377 PHE G CB 1 ATOM 2868 C CG . PHE B 2 207 ? -54.030 -29.452 8.198 1.00 99.12 ? 377 PHE G CG 1 ATOM 2869 C CD1 . PHE B 2 207 ? -55.062 -28.619 8.582 1.00 99.12 ? 377 PHE G CD1 1 ATOM 2870 C CD2 . PHE B 2 207 ? -53.429 -30.262 9.169 1.00 99.12 ? 377 PHE G CD2 1 ATOM 2871 C CE1 . PHE B 2 207 ? -55.479 -28.574 9.892 1.00 99.12 ? 377 PHE G CE1 1 ATOM 2872 C CE2 . PHE B 2 207 ? -53.848 -30.229 10.480 1.00 99.12 ? 377 PHE G CE2 1 ATOM 2873 C CZ . PHE B 2 207 ? -54.862 -29.384 10.837 1.00 99.12 ? 377 PHE G CZ 1 ATOM 2874 N N . TYR B 2 208 ? -50.954 -29.837 4.883 1.00 95.70 ? 378 TYR G N 1 ATOM 2875 C CA . TYR B 2 208 ? -50.459 -30.506 3.654 1.00 95.70 ? 378 TYR G CA 1 ATOM 2876 C C . TYR B 2 208 ? -50.363 -32.022 4.038 1.00 95.70 ? 378 TYR G C 1 ATOM 2877 O O . TYR B 2 208 ? -50.008 -32.283 5.155 1.00 95.70 ? 378 TYR G O 1 ATOM 2878 C CB . TYR B 2 208 ? -49.112 -29.886 3.506 1.00 86.34 ? 378 TYR G CB 1 ATOM 2879 C CG . TYR B 2 208 ? -49.248 -28.446 3.116 1.00 86.34 ? 378 TYR G CG 1 ATOM 2880 C CD1 . TYR B 2 208 ? -49.435 -27.480 4.135 1.00 86.34 ? 378 TYR G CD1 1 ATOM 2881 C CD2 . TYR B 2 208 ? -49.027 -27.996 1.845 1.00 86.34 ? 378 TYR G CD2 1 ATOM 2882 C CE1 . TYR B 2 208 ? -49.434 -26.124 3.892 1.00 86.34 ? 378 TYR G CE1 1 ATOM 2883 C CE2 . TYR B 2 208 ? -48.990 -26.588 1.586 1.00 86.34 ? 378 TYR G CE2 1 ATOM 2884 C CZ . TYR B 2 208 ? -49.210 -25.666 2.617 1.00 86.34 ? 378 TYR G CZ 1 ATOM 2885 O OH . TYR B 2 208 ? -49.240 -24.304 2.351 1.00 86.34 ? 378 TYR G OH 1 ATOM 2886 N N . CYS B 2 209 ? -50.707 -33.020 3.229 1.00 111.95 ? 379 CYS G N 1 ATOM 2887 C CA . CYS B 2 209 ? -50.358 -34.422 3.622 1.00 111.95 ? 379 CYS G CA 1 ATOM 2888 C C . CYS B 2 209 ? -49.454 -34.964 2.508 1.00 111.95 ? 379 CYS G C 1 ATOM 2889 O O . CYS B 2 209 ? -49.824 -34.784 1.353 1.00 111.95 ? 379 CYS G O 1 ATOM 2890 C CB . CYS B 2 209 ? -51.552 -35.382 3.853 1.00 127.28 ? 379 CYS G CB 1 ATOM 2891 S SG . CYS B 2 209 ? -52.495 -35.352 5.439 1.00 127.28 ? 379 CYS G SG 1 ATOM 2892 N N . ASN B 2 210 ? -48.377 -35.735 2.795 1.00 148.51 ? 380 ASN G N 1 ATOM 2893 C CA . ASN B 2 210 ? -47.474 -36.155 1.681 1.00 148.51 ? 380 ASN G CA 1 ATOM 2894 C C . ASN B 2 210 ? -48.413 -37.366 1.397 1.00 148.51 ? 380 ASN G C 1 ATOM 2895 O O . ASN B 2 210 ? -48.364 -38.366 2.089 1.00 148.51 ? 380 ASN G O 1 ATOM 2896 C CB . ASN B 2 210 ? -45.980 -36.532 2.225 1.00 92.92 ? 380 ASN G CB 1 ATOM 2897 C CG . ASN B 2 210 ? -44.873 -36.750 1.035 1.00 92.92 ? 380 ASN G CG 1 ATOM 2898 O OD1 . ASN B 2 210 ? -45.241 -36.349 -0.049 1.00 92.92 ? 380 ASN G OD1 1 ATOM 2899 N ND2 . ASN B 2 210 ? -43.610 -37.292 1.210 1.00 92.92 ? 380 ASN G ND2 1 ATOM 2900 N N . THR B 2 211 ? -49.294 -37.228 0.395 1.00 105.22 ? 381 THR G N 1 ATOM 2901 C CA . THR B 2 211 ? -50.292 -38.245 -0.007 1.00 105.22 ? 381 THR G CA 1 ATOM 2902 C C . THR B 2 211 ? -49.682 -38.910 -1.202 1.00 105.22 ? 381 THR G C 1 ATOM 2903 O O . THR B 2 211 ? -50.334 -39.536 -2.038 1.00 105.22 ? 381 THR G O 1 ATOM 2904 C CB . THR B 2 211 ? -51.677 -37.720 -0.398 1.00 94.86 ? 381 THR G CB 1 ATOM 2905 O OG1 . THR B 2 211 ? -51.614 -37.007 -1.633 1.00 94.86 ? 381 THR G OG1 1 ATOM 2906 C CG2 . THR B 2 211 ? -52.174 -36.801 0.676 1.00 94.86 ? 381 THR G CG2 1 ATOM 2907 N N . THR B 2 212 ? -48.432 -38.554 -1.376 1.00 158.91 ? 382 THR G N 1 ATOM 2908 C CA . THR B 2 212 ? -47.619 -39.110 -2.415 1.00 158.91 ? 382 THR G CA 1 ATOM 2909 C C . THR B 2 212 ? -47.705 -40.559 -1.973 1.00 158.91 ? 382 THR G C 1 ATOM 2910 O O . THR B 2 212 ? -47.723 -41.496 -2.792 1.00 158.91 ? 382 THR G O 1 ATOM 2911 C CB . THR B 2 212 ? -46.181 -38.510 -2.321 1.00 179.40 ? 382 THR G CB 1 ATOM 2912 O OG1 . THR B 2 212 ? -45.613 -38.808 -1.035 1.00 179.40 ? 382 THR G OG1 1 ATOM 2913 C CG2 . THR B 2 212 ? -46.196 -37.005 -2.584 1.00 179.40 ? 382 THR G CG2 1 ATOM 2914 N N . LYS B 2 213 ? -47.640 -40.714 -0.653 1.00 129.78 ? 383 LYS G N 1 ATOM 2915 C CA . LYS B 2 213 ? -47.655 -42.016 -0.007 1.00 129.78 ? 383 LYS G CA 1 ATOM 2916 C C . LYS B 2 213 ? -48.934 -42.829 -0.271 1.00 129.78 ? 383 LYS G C 1 ATOM 2917 O O . LYS B 2 213 ? -48.883 -44.038 -0.555 1.00 129.78 ? 383 LYS G O 1 ATOM 2918 C CB . LYS B 2 213 ? -47.601 -41.689 1.469 1.00 155.10 ? 383 LYS G CB 1 ATOM 2919 C CG . LYS B 2 213 ? -46.309 -40.984 1.725 1.00 155.10 ? 383 LYS G CG 1 ATOM 2920 C CD . LYS B 2 213 ? -46.050 -40.567 3.134 1.00 155.10 ? 383 LYS G CD 1 ATOM 2921 C CE . LYS B 2 213 ? -44.692 -39.882 3.121 1.00 155.10 ? 383 LYS G CE 1 ATOM 2922 N NZ . LYS B 2 213 ? -44.303 -39.245 4.389 1.00 155.10 ? 383 LYS G NZ 1 ATOM 2923 N N . LEU B 2 214 ? -50.072 -42.147 -0.265 1.00 115.24 ? 384 LEU G N 1 ATOM 2924 C CA . LEU B 2 214 ? -51.336 -42.824 -0.517 1.00 115.24 ? 384 LEU G CA 1 ATOM 2925 C C . LEU B 2 214 ? -51.564 -43.431 -1.906 1.00 115.24 ? 384 LEU G C 1 ATOM 2926 O O . LEU B 2 214 ? -52.139 -44.510 -2.023 1.00 115.24 ? 384 LEU G O 1 ATOM 2927 C CB . LEU B 2 214 ? -52.530 -41.951 -0.101 1.00 108.70 ? 384 LEU G CB 1 ATOM 2928 C CG . LEU B 2 214 ? -53.862 -42.654 -0.361 1.00 108.70 ? 384 LEU G CG 1 ATOM 2929 C CD1 . LEU B 2 214 ? -54.863 -42.145 0.685 1.00 108.70 ? 384 LEU G CD1 1 ATOM 2930 C CD2 . LEU B 2 214 ? -54.315 -42.462 -1.831 1.00 108.70 ? 384 LEU G CD2 1 ATOM 2931 N N . PHE B 2 215 ? -51.156 -42.764 -2.981 1.00 112.05 ? 385 PHE G N 1 ATOM 2932 C CA . PHE B 2 215 ? -51.456 -43.470 -4.193 1.00 112.05 ? 385 PHE G CA 1 ATOM 2933 C C . PHE B 2 215 ? -50.059 -44.093 -4.502 1.00 112.05 ? 385 PHE G C 1 ATOM 2934 O O . PHE B 2 215 ? -49.110 -43.419 -4.946 1.00 112.05 ? 385 PHE G O 1 ATOM 2935 C CB . PHE B 2 215 ? -51.762 -42.460 -5.285 1.00 82.25 ? 385 PHE G CB 1 ATOM 2936 C CG . PHE B 2 215 ? -52.928 -41.567 -4.984 1.00 82.25 ? 385 PHE G CG 1 ATOM 2937 C CD1 . PHE B 2 215 ? -52.707 -40.276 -4.512 1.00 82.25 ? 385 PHE G CD1 1 ATOM 2938 C CD2 . PHE B 2 215 ? -54.232 -42.021 -5.068 1.00 82.25 ? 385 PHE G CD2 1 ATOM 2939 C CE1 . PHE B 2 215 ? -53.771 -39.452 -4.151 1.00 82.25 ? 385 PHE G CE1 1 ATOM 2940 C CE2 . PHE B 2 215 ? -55.306 -41.197 -4.694 1.00 82.25 ? 385 PHE G CE2 1 ATOM 2941 C CZ . PHE B 2 215 ? -55.071 -39.917 -4.241 1.00 82.25 ? 385 PHE G CZ 1 ATOM 2942 N N . ASN B 2 216 ? -49.971 -45.396 -4.315 1.00 118.55 ? 386 ASN G N 1 ATOM 2943 C CA . ASN B 2 216 ? -48.784 -46.195 -4.577 1.00 118.55 ? 386 ASN G CA 1 ATOM 2944 C C . ASN B 2 216 ? -49.109 -47.547 -5.209 1.00 118.55 ? 386 ASN G C 1 ATOM 2945 O O . ASN B 2 216 ? -48.298 -48.487 -5.297 1.00 118.55 ? 386 ASN G O 1 ATOM 2946 C CB . ASN B 2 216 ? -47.907 -46.184 -3.296 1.00 115.64 ? 386 ASN G CB 1 ATOM 2947 C CG . ASN B 2 216 ? -48.618 -46.727 -2.080 1.00 115.64 ? 386 ASN G CG 1 ATOM 2948 O OD1 . ASN B 2 216 ? -49.839 -46.711 -2.029 1.00 115.64 ? 386 ASN G OD1 1 ATOM 2949 N ND2 . ASN B 2 216 ? -47.857 -47.189 -1.085 1.00 115.64 ? 386 ASN G ND2 1 ATOM 2950 N N . SER B 2 217 ? -50.313 -47.550 -5.738 1.00 145.33 ? 387 SER G N 1 ATOM 2951 C CA . SER B 2 217 ? -50.992 -48.704 -6.262 1.00 145.33 ? 387 SER G CA 1 ATOM 2952 C C . SER B 2 217 ? -51.059 -48.764 -7.762 1.00 145.33 ? 387 SER G C 1 ATOM 2953 O O . SER B 2 217 ? -51.249 -47.746 -8.416 1.00 145.33 ? 387 SER G O 1 ATOM 2954 C CB . SER B 2 217 ? -52.409 -48.733 -5.683 1.00 141.61 ? 387 SER G CB 1 ATOM 2955 O OG . SER B 2 217 ? -53.219 -49.708 -6.310 1.00 141.61 ? 387 SER G OG 1 ATOM 2956 N N . ILE B 2 218 ? -50.894 -49.957 -8.326 1.00 137.61 ? 388 ILE G N 1 ATOM 2957 C CA . ILE B 2 218 ? -50.949 -50.058 -9.777 1.00 137.61 ? 388 ILE G CA 1 ATOM 2958 C C . ILE B 2 218 ? -51.929 -51.188 -10.096 1.00 137.61 ? 388 ILE G C 1 ATOM 2959 O O . ILE B 2 218 ? -52.212 -52.059 -9.250 1.00 137.61 ? 388 ILE G O 1 ATOM 2960 C CB . ILE B 2 218 ? -49.553 -50.437 -10.320 1.00 155.90 ? 388 ILE G CB 1 ATOM 2961 C CG1 . ILE B 2 218 ? -49.087 -51.793 -9.746 1.00 155.90 ? 388 ILE G CG1 1 ATOM 2962 C CG2 . ILE B 2 218 ? -48.545 -49.391 -9.882 1.00 155.90 ? 388 ILE G CG2 1 ATOM 2963 C CD1 . ILE B 2 218 ? -48.727 -51.801 -8.233 1.00 155.90 ? 388 ILE G CD1 1 ATOM 2964 N N . HIS B 2 219 ? -52.447 -51.176 -11.326 1.00 127.90 ? 389 HIS G N 1 ATOM 2965 C CA . HIS B 2 219 ? -53.454 -52.171 -11.675 1.00 127.90 ? 389 HIS G CA 1 ATOM 2966 C C . HIS B 2 219 ? -53.636 -53.164 -12.854 1.00 127.90 ? 389 HIS G C 1 ATOM 2967 O O . HIS B 2 219 ? -53.485 -52.868 -14.061 1.00 127.90 ? 389 HIS G O 1 ATOM 2968 C CB . HIS B 2 219 ? -54.833 -51.517 -11.462 1.00 128.89 ? 389 HIS G CB 1 ATOM 2969 C CG . HIS B 2 219 ? -55.191 -51.273 -10.018 1.00 128.89 ? 389 HIS G CG 1 ATOM 2970 N ND1 . HIS B 2 219 ? -54.879 -50.115 -9.340 1.00 128.89 ? 389 HIS G ND1 1 ATOM 2971 C CD2 . HIS B 2 219 ? -55.909 -52.024 -9.147 1.00 128.89 ? 389 HIS G CD2 1 ATOM 2972 C CE1 . HIS B 2 219 ? -55.390 -50.160 -8.120 1.00 128.89 ? 389 HIS G CE1 1 ATOM 2973 N NE2 . HIS B 2 219 ? -56.022 -51.308 -7.978 1.00 128.89 ? 389 HIS G NE2 1 ATOM 2974 N N . ASN B 2 220 ? -53.974 -54.365 -12.370 1.00 201.57 ? 390 ASN G N 1 ATOM 2975 C CA . ASN B 2 220 ? -54.445 -55.568 -13.053 1.00 201.57 ? 390 ASN G CA 1 ATOM 2976 C C . ASN B 2 220 ? -53.893 -56.338 -14.284 1.00 201.57 ? 390 ASN G C 1 ATOM 2977 O O . ASN B 2 220 ? -54.685 -56.771 -15.125 1.00 201.57 ? 390 ASN G O 1 ATOM 2978 C CB . ASN B 2 220 ? -55.963 -55.377 -13.174 1.00 139.79 ? 390 ASN G CB 1 ATOM 2979 C CG . ASN B 2 220 ? -56.682 -55.477 -11.798 1.00 139.79 ? 390 ASN G CG 1 ATOM 2980 O OD1 . ASN B 2 220 ? -57.880 -55.161 -11.665 1.00 139.79 ? 390 ASN G OD1 1 ATOM 2981 N ND2 . ASN B 2 220 ? -55.936 -55.898 -10.773 1.00 139.79 ? 390 ASN G ND2 1 ATOM 2982 N N . SER B 2 221 ? -52.581 -56.503 -14.433 1.00 164.12 ? 391 SER G N 1 ATOM 2983 C CA . SER B 2 221 ? -52.059 -57.265 -15.595 1.00 164.12 ? 391 SER G CA 1 ATOM 2984 C C . SER B 2 221 ? -50.614 -57.775 -15.413 1.00 164.12 ? 391 SER G C 1 ATOM 2985 O O . SER B 2 221 ? -50.283 -58.909 -15.784 1.00 164.12 ? 391 SER G O 1 ATOM 2986 C CB . SER B 2 221 ? -52.153 -56.432 -16.910 1.00 78.58 ? 391 SER G CB 1 ATOM 2987 O OG . SER B 2 221 ? -53.119 -56.946 -17.826 1.00 78.58 ? 391 SER G OG 1 ATOM 2988 N N . ILE B 2 243 ? -53.202 -47.651 6.378 1.00 124.01 ? 413 ILE G N 1 ATOM 2989 C CA . ILE B 2 243 ? -52.683 -46.609 5.494 1.00 124.01 ? 413 ILE G CA 1 ATOM 2990 C C . ILE B 2 243 ? -52.822 -45.248 6.146 1.00 124.01 ? 413 ILE G C 1 ATOM 2991 O O . ILE B 2 243 ? -53.938 -44.731 6.262 1.00 124.01 ? 413 ILE G O 1 ATOM 2992 C CB . ILE B 2 243 ? -53.438 -46.660 4.209 1.00 108.47 ? 413 ILE G CB 1 ATOM 2993 C CG1 . ILE B 2 243 ? -53.185 -48.032 3.570 1.00 108.47 ? 413 ILE G CG1 1 ATOM 2994 C CG2 . ILE B 2 243 ? -53.036 -45.462 3.372 1.00 108.47 ? 413 ILE G CG2 1 ATOM 2995 C CD1 . ILE B 2 243 ? -54.029 -48.373 2.396 1.00 108.47 ? 413 ILE G CD1 1 ATOM 2996 N N . THR B 2 244 ? -51.678 -44.686 6.569 1.00 147.83 ? 414 THR G N 1 ATOM 2997 C CA . THR B 2 244 ? -51.623 -43.390 7.267 1.00 147.83 ? 414 THR G CA 1 ATOM 2998 C C . THR B 2 244 ? -50.815 -42.247 6.637 1.00 147.83 ? 414 THR G C 1 ATOM 2999 O O . THR B 2 244 ? -49.678 -42.427 6.210 1.00 147.83 ? 414 THR G O 1 ATOM 3000 C CB . THR B 2 244 ? -51.098 -43.557 8.675 1.00 97.06 ? 414 THR G CB 1 ATOM 3001 O OG1 . THR B 2 244 ? -51.966 -44.437 9.397 1.00 97.06 ? 414 THR G OG1 1 ATOM 3002 C CG2 . THR B 2 244 ? -51.118 -42.202 9.390 1.00 97.06 ? 414 THR G CG2 1 ATOM 3003 N N . LEU B 2 245 ? -51.456 -41.087 6.538 1.00 119.91 ? 415 LEU G N 1 ATOM 3004 C CA . LEU B 2 245 ? -50.874 -39.877 5.977 1.00 119.91 ? 415 LEU G CA 1 ATOM 3005 C C . LEU B 2 245 ? -50.072 -39.011 7.007 1.00 119.91 ? 415 LEU G C 1 ATOM 3006 O O . LEU B 2 245 ? -50.548 -38.768 8.134 1.00 119.91 ? 415 LEU G O 1 ATOM 3007 C CB . LEU B 2 245 ? -52.015 -39.085 5.293 1.00 77.95 ? 415 LEU G CB 1 ATOM 3008 C CG . LEU B 2 245 ? -52.819 -39.774 4.121 1.00 77.95 ? 415 LEU G CG 1 ATOM 3009 C CD1 . LEU B 2 245 ? -53.056 -38.834 3.004 1.00 77.95 ? 415 LEU G CD1 1 ATOM 3010 C CD2 . LEU B 2 245 ? -52.144 -41.002 3.562 1.00 77.95 ? 415 LEU G CD2 1 ATOM 3011 N N . PRO B 2 246 ? -48.834 -38.570 6.647 1.00 112.33 ? 416 PRO G N 1 ATOM 3012 C CA . PRO B 2 246 ? -47.922 -37.740 7.463 1.00 112.33 ? 416 PRO G CA 1 ATOM 3013 C C . PRO B 2 246 ? -48.053 -36.239 7.216 1.00 112.33 ? 416 PRO G C 1 ATOM 3014 O O . PRO B 2 246 ? -47.205 -35.632 6.558 1.00 112.33 ? 416 PRO G O 1 ATOM 3015 C CB . PRO B 2 246 ? -46.556 -38.238 7.038 1.00 142.01 ? 416 PRO G CB 1 ATOM 3016 C CG . PRO B 2 246 ? -46.749 -38.432 5.575 1.00 142.01 ? 416 PRO G CG 1 ATOM 3017 C CD . PRO B 2 246 ? -48.088 -39.160 5.517 1.00 142.01 ? 416 PRO G CD 1 ATOM 3018 N N . CYS B 2 247 ? -49.119 -35.652 7.744 1.00 153.35 ? 417 CYS G N 1 ATOM 3019 C CA . CYS B 2 247 ? -49.392 -34.228 7.584 1.00 153.35 ? 417 CYS G CA 1 ATOM 3020 C C . CYS B 2 247 ? -48.485 -33.251 8.350 1.00 153.35 ? 417 CYS G C 1 ATOM 3021 O O . CYS B 2 247 ? -47.957 -33.579 9.406 1.00 153.35 ? 417 CYS G O 1 ATOM 3022 C CB . CYS B 2 247 ? -50.880 -33.926 7.826 1.00 209.93 ? 417 CYS G CB 1 ATOM 3023 S SG . CYS B 2 247 ? -52.037 -33.632 6.419 1.00 209.93 ? 417 CYS G SG 1 ATOM 3024 N N . ARG B 2 248 ? -48.310 -32.062 7.763 1.00 114.17 ? 418 ARG G N 1 ATOM 3025 C CA . ARG B 2 248 ? -47.451 -30.952 8.201 1.00 114.17 ? 418 ARG G CA 1 ATOM 3026 C C . ARG B 2 248 ? -48.383 -29.743 8.503 1.00 114.17 ? 418 ARG G C 1 ATOM 3027 O O . ARG B 2 248 ? -49.298 -29.515 7.748 1.00 114.17 ? 418 ARG G O 1 ATOM 3028 C CB . ARG B 2 248 ? -46.638 -30.575 6.993 1.00 113.93 ? 418 ARG G CB 1 ATOM 3029 C CG . ARG B 2 248 ? -45.747 -31.670 6.451 1.00 113.93 ? 418 ARG G CG 1 ATOM 3030 C CD . ARG B 2 248 ? -44.976 -31.173 5.233 1.00 113.93 ? 418 ARG G CD 1 ATOM 3031 N NE . ARG B 2 248 ? -44.254 -32.247 4.560 1.00 113.93 ? 418 ARG G NE 1 ATOM 3032 C CZ . ARG B 2 248 ? -44.328 -32.482 3.244 1.00 113.93 ? 418 ARG G CZ 1 ATOM 3033 N NH1 . ARG B 2 248 ? -45.061 -31.716 2.466 1.00 113.93 ? 418 ARG G NH1 1 ATOM 3034 N NH2 . ARG B 2 248 ? -43.713 -33.513 2.695 1.00 113.93 ? 418 ARG G NH2 1 ATOM 3035 N N . ILE B 2 249 ? -48.146 -28.917 9.518 1.00 127.32 ? 419 ILE G N 1 ATOM 3036 C CA . ILE B 2 249 ? -49.066 -27.777 9.766 1.00 127.32 ? 419 ILE G CA 1 ATOM 3037 C C . ILE B 2 249 ? -48.203 -26.629 9.381 1.00 127.32 ? 419 ILE G C 1 ATOM 3038 O O . ILE B 2 249 ? -47.105 -26.518 9.899 1.00 127.32 ? 419 ILE G O 1 ATOM 3039 C CB . ILE B 2 249 ? -49.418 -27.579 11.304 1.00 166.09 ? 419 ILE G CB 1 ATOM 3040 C CG1 . ILE B 2 249 ? -50.099 -28.810 11.903 1.00 166.09 ? 419 ILE G CG1 1 ATOM 3041 C CG2 . ILE B 2 249 ? -50.091 -26.267 11.532 1.00 166.09 ? 419 ILE G CG2 1 ATOM 3042 C CD1 . ILE B 2 249 ? -50.237 -28.760 13.446 1.00 166.09 ? 419 ILE G CD1 1 ATOM 3043 N N . ARG B 2 250 ? -48.688 -25.714 8.536 1.00 100.49 ? 420 ARG G N 1 ATOM 3044 C CA . ARG B 2 250 ? -47.692 -24.759 8.142 1.00 100.49 ? 420 ARG G CA 1 ATOM 3045 C C . ARG B 2 250 ? -48.397 -23.370 8.329 1.00 100.49 ? 420 ARG G C 1 ATOM 3046 O O . ARG B 2 250 ? -49.555 -23.269 8.047 1.00 100.49 ? 420 ARG G O 1 ATOM 3047 C CB . ARG B 2 250 ? -47.415 -25.192 6.702 1.00 260.50 ? 420 ARG G CB 1 ATOM 3048 C CG . ARG B 2 250 ? -46.919 -26.657 6.887 1.00 260.50 ? 420 ARG G CG 1 ATOM 3049 C CD . ARG B 2 250 ? -46.491 -27.609 5.796 1.00 260.50 ? 420 ARG G CD 1 ATOM 3050 N NE . ARG B 2 250 ? -45.241 -27.278 5.144 1.00 260.50 ? 420 ARG G NE 1 ATOM 3051 C CZ . ARG B 2 250 ? -44.922 -26.191 4.472 1.00 260.50 ? 420 ARG G CZ 1 ATOM 3052 N NH1 . ARG B 2 250 ? -45.781 -25.204 4.297 1.00 260.50 ? 420 ARG G NH1 1 ATOM 3053 N NH2 . ARG B 2 250 ? -43.686 -26.097 4.012 1.00 260.50 ? 420 ARG G NH2 1 ATOM 3054 N N . GLN B 2 251 ? -47.757 -22.341 8.879 1.00 86.95 ? 421 GLN G N 1 ATOM 3055 C CA . GLN B 2 251 ? -48.353 -21.001 8.987 1.00 86.95 ? 421 GLN G CA 1 ATOM 3056 C C . GLN B 2 251 ? -48.101 -20.036 7.786 1.00 86.95 ? 421 GLN G C 1 ATOM 3057 O O . GLN B 2 251 ? -48.661 -18.961 7.739 1.00 86.95 ? 421 GLN G O 1 ATOM 3058 C CB . GLN B 2 251 ? -47.943 -20.276 10.260 1.00 122.07 ? 421 GLN G CB 1 ATOM 3059 C CG . GLN B 2 251 ? -46.453 -19.965 10.287 1.00 122.07 ? 421 GLN G CG 1 ATOM 3060 C CD . GLN B 2 251 ? -45.990 -19.240 11.541 1.00 122.07 ? 421 GLN G CD 1 ATOM 3061 O OE1 . GLN B 2 251 ? -46.444 -19.532 12.664 1.00 122.07 ? 421 GLN G OE1 1 ATOM 3062 N NE2 . GLN B 2 251 ? -45.053 -18.294 11.358 1.00 122.07 ? 421 GLN G NE2 1 ATOM 3063 N N . ILE B 2 252 ? -47.229 -20.365 6.846 1.00 74.36 ? 422 ILE G N 1 ATOM 3064 C CA . ILE B 2 252 ? -47.023 -19.503 5.681 1.00 74.36 ? 422 ILE G CA 1 ATOM 3065 C C . ILE B 2 252 ? -47.329 -20.206 4.445 1.00 74.36 ? 422 ILE G C 1 ATOM 3066 O O . ILE B 2 252 ? -46.683 -21.184 4.067 1.00 74.36 ? 422 ILE G O 1 ATOM 3067 C CB . ILE B 2 252 ? -45.663 -18.788 5.538 1.00 53.76 ? 422 ILE G CB 1 ATOM 3068 C CG1 . ILE B 2 252 ? -45.450 -17.888 6.749 1.00 53.76 ? 422 ILE G CG1 1 ATOM 3069 C CG2 . ILE B 2 252 ? -45.524 -18.158 4.143 1.00 53.76 ? 422 ILE G CG2 1 ATOM 3070 C CD1 . ILE B 2 252 ? -44.084 -17.321 6.779 1.00 53.76 ? 422 ILE G CD1 1 ATOM 3071 N N . ILE B 2 253 ? -48.265 -19.591 3.744 1.00 89.13 ? 423 ILE G N 1 ATOM 3072 C CA . ILE B 2 253 ? -48.868 -20.275 2.651 1.00 89.13 ? 423 ILE G CA 1 ATOM 3073 C C . ILE B 2 253 ? -49.125 -19.441 1.436 1.00 89.13 ? 423 ILE G C 1 ATOM 3074 O O . ILE B 2 253 ? -49.264 -18.225 1.544 1.00 89.13 ? 423 ILE G O 1 ATOM 3075 C CB . ILE B 2 253 ? -50.170 -20.790 3.227 1.00 54.29 ? 423 ILE G CB 1 ATOM 3076 C CG1 . ILE B 2 253 ? -50.825 -21.736 2.291 1.00 54.29 ? 423 ILE G CG1 1 ATOM 3077 C CG2 . ILE B 2 253 ? -51.073 -19.634 3.558 1.00 54.29 ? 423 ILE G CG2 1 ATOM 3078 C CD1 . ILE B 2 253 ? -51.980 -22.395 3.031 1.00 54.29 ? 423 ILE G CD1 1 ATOM 3079 N N . ASN B 2 254 ? -49.057 -20.099 0.280 1.00 109.67 ? 424 ASN G N 1 ATOM 3080 C CA . ASN B 2 254 ? -49.366 -19.500 -1.015 1.00 109.67 ? 424 ASN G CA 1 ATOM 3081 C C . ASN B 2 254 ? -50.829 -19.234 -1.243 1.00 109.67 ? 424 ASN G C 1 ATOM 3082 O O . ASN B 2 254 ? -51.701 -19.870 -0.646 1.00 109.67 ? 424 ASN G O 1 ATOM 3083 C CB . ASN B 2 254 ? -48.806 -20.366 -2.098 1.00 82.67 ? 424 ASN G CB 1 ATOM 3084 C CG . ASN B 2 254 ? -47.317 -20.314 -2.124 1.00 82.67 ? 424 ASN G CG 1 ATOM 3085 O OD1 . ASN B 2 254 ? -46.717 -19.284 -1.762 1.00 82.67 ? 424 ASN G OD1 1 ATOM 3086 N ND2 . ASN B 2 254 ? -46.695 -21.431 -2.487 1.00 82.67 ? 424 ASN G ND2 1 ATOM 3087 N N . MET B 2 255 ? -51.147 -18.293 -2.093 1.00 85.79 ? 425 MET G N 1 ATOM 3088 C CA . MET B 2 255 ? -52.529 -18.106 -2.178 1.00 85.79 ? 425 MET G CA 1 ATOM 3089 C C . MET B 2 255 ? -53.129 -18.635 -3.449 1.00 85.79 ? 425 MET G C 1 ATOM 3090 O O . MET B 2 255 ? -52.545 -18.510 -4.486 1.00 85.79 ? 425 MET G O 1 ATOM 3091 C CB . MET B 2 255 ? -52.820 -16.636 -2.029 1.00 73.02 ? 425 MET G CB 1 ATOM 3092 C CG . MET B 2 255 ? -52.587 -16.095 -0.673 1.00 73.02 ? 425 MET G CG 1 ATOM 3093 S SD . MET B 2 255 ? -52.978 -14.379 -0.622 1.00 73.02 ? 425 MET G SD 1 ATOM 3094 C CE . MET B 2 255 ? -51.656 -13.729 -1.749 1.00 73.02 ? 425 MET G CE 1 ATOM 3095 N N . TRP B 2 256 ? -54.221 -19.368 -3.311 1.00 91.24 ? 426 TRP G N 1 ATOM 3096 C CA . TRP B 2 256 ? -55.062 -19.854 -4.400 1.00 91.24 ? 426 TRP G CA 1 ATOM 3097 C C . TRP B 2 256 ? -55.814 -18.734 -5.055 1.00 91.24 ? 426 TRP G C 1 ATOM 3098 O O . TRP B 2 256 ? -56.161 -18.772 -6.253 1.00 91.24 ? 426 TRP G O 1 ATOM 3099 C CB . TRP B 2 256 ? -55.999 -20.856 -3.768 1.00 86.75 ? 426 TRP G CB 1 ATOM 3100 C CG . TRP B 2 256 ? -56.815 -20.208 -2.715 1.00 86.75 ? 426 TRP G CG 1 ATOM 3101 C CD1 . TRP B 2 256 ? -56.382 -19.950 -1.456 1.00 86.75 ? 426 TRP G CD1 1 ATOM 3102 C CD2 . TRP B 2 256 ? -58.194 -19.879 -2.738 1.00 86.75 ? 426 TRP G CD2 1 ATOM 3103 N NE1 . TRP B 2 256 ? -57.406 -19.500 -0.688 1.00 86.75 ? 426 TRP G NE1 1 ATOM 3104 C CE2 . TRP B 2 256 ? -58.537 -19.445 -1.450 1.00 86.75 ? 426 TRP G CE2 1 ATOM 3105 C CE3 . TRP B 2 256 ? -59.171 -19.906 -3.712 1.00 86.75 ? 426 TRP G CE3 1 ATOM 3106 C CZ2 . TRP B 2 256 ? -59.820 -19.040 -1.107 1.00 86.75 ? 426 TRP G CZ2 1 ATOM 3107 C CZ3 . TRP B 2 256 ? -60.443 -19.497 -3.379 1.00 86.75 ? 426 TRP G CZ3 1 ATOM 3108 C CH2 . TRP B 2 256 ? -60.761 -19.067 -2.081 1.00 86.75 ? 426 TRP G CH2 1 ATOM 3109 N N . GLN B 2 257 ? -56.079 -17.760 -4.200 1.00 61.15 ? 427 GLN G N 1 ATOM 3110 C CA . GLN B 2 257 ? -56.782 -16.544 -4.523 1.00 61.15 ? 427 GLN G CA 1 ATOM 3111 C C . GLN B 2 257 ? -56.248 -15.579 -5.579 1.00 61.15 ? 427 GLN G C 1 ATOM 3112 O O . GLN B 2 257 ? -57.024 -15.065 -6.356 1.00 61.15 ? 427 GLN G O 1 ATOM 3113 C CB . GLN B 2 257 ? -56.796 -15.746 -3.265 1.00 81.03 ? 427 GLN G CB 1 ATOM 3114 C CG . GLN B 2 257 ? -57.608 -16.185 -2.147 1.00 81.03 ? 427 GLN G CG 1 ATOM 3115 C CD . GLN B 2 257 ? -57.430 -15.190 -1.010 1.00 81.03 ? 427 GLN G CD 1 ATOM 3116 O OE1 . GLN B 2 257 ? -56.330 -15.103 -0.413 1.00 81.03 ? 427 GLN G OE1 1 ATOM 3117 N NE2 . GLN B 2 257 ? -58.464 -14.405 -0.733 1.00 81.03 ? 427 GLN G NE2 1 ATOM 3118 N N . GLU B 2 258 ? -54.922 -15.378 -5.594 1.00 123.48 ? 428 GLU G N 1 ATOM 3119 C CA . GLU B 2 258 ? -54.144 -14.425 -6.436 1.00 123.48 ? 428 GLU G CA 1 ATOM 3120 C C . GLU B 2 258 ? -52.729 -14.969 -6.410 1.00 123.48 ? 428 GLU G C 1 ATOM 3121 O O . GLU B 2 258 ? -52.469 -15.851 -5.613 1.00 123.48 ? 428 GLU G O 1 ATOM 3122 C CB . GLU B 2 258 ? -54.245 -12.969 -5.909 1.00 110.20 ? 428 GLU G CB 1 ATOM 3123 C CG . GLU B 2 258 ? -53.671 -12.641 -4.536 1.00 110.20 ? 428 GLU G CG 1 ATOM 3124 C CD . GLU B 2 258 ? -53.850 -11.161 -4.160 1.00 110.20 ? 428 GLU G CD 1 ATOM 3125 O OE1 . GLU B 2 258 ? -53.628 -10.836 -2.974 1.00 110.20 ? 428 GLU G OE1 1 ATOM 3126 O OE2 . GLU B 2 258 ? -54.217 -10.331 -5.031 1.00 110.20 ? 428 GLU G OE2 1 ATOM 3127 N N . VAL B 2 259 ? -51.786 -14.490 -7.211 1.00 72.41 ? 429 VAL G N 1 ATOM 3128 C CA . VAL B 2 259 ? -50.479 -15.172 -7.201 1.00 72.41 ? 429 VAL G CA 1 ATOM 3129 C C . VAL B 2 259 ? -49.542 -14.551 -6.223 1.00 72.41 ? 429 VAL G C 1 ATOM 3130 O O . VAL B 2 259 ? -49.215 -13.370 -6.306 1.00 72.41 ? 429 VAL G O 1 ATOM 3131 C CB . VAL B 2 259 ? -49.771 -15.027 -8.540 1.00 78.96 ? 429 VAL G CB 1 ATOM 3132 C CG1 . VAL B 2 259 ? -48.460 -15.735 -8.468 1.00 78.96 ? 429 VAL G CG1 1 ATOM 3133 C CG2 . VAL B 2 259 ? -50.655 -15.464 -9.689 1.00 78.96 ? 429 VAL G CG2 1 ATOM 3134 N N . GLY B 2 260 ? -49.126 -15.384 -5.281 1.00 93.86 ? 430 GLY G N 1 ATOM 3135 C CA . GLY B 2 260 ? -48.181 -14.953 -4.272 1.00 93.86 ? 430 GLY G CA 1 ATOM 3136 C C . GLY B 2 260 ? -48.285 -15.634 -2.918 1.00 93.86 ? 430 GLY G C 1 ATOM 3137 O O . GLY B 2 260 ? -49.060 -16.585 -2.754 1.00 93.86 ? 430 GLY G O 1 ATOM 3138 N N . ARG B 2 261 ? -47.501 -15.135 -1.953 1.00 46.68 ? 431 ARG G N 1 ATOM 3139 C CA . ARG B 2 261 ? -47.597 -15.591 -0.617 1.00 46.68 ? 431 ARG G CA 1 ATOM 3140 C C . ARG B 2 261 ? -48.378 -14.775 0.430 1.00 46.68 ? 431 ARG G C 1 ATOM 3141 O O . ARG B 2 261 ? -48.331 -13.554 0.462 1.00 46.68 ? 431 ARG G O 1 ATOM 3142 C CB . ARG B 2 261 ? -46.272 -15.962 -0.008 1.00 88.07 ? 431 ARG G CB 1 ATOM 3143 C CG . ARG B 2 261 ? -45.652 -17.165 -0.544 1.00 88.07 ? 431 ARG G CG 1 ATOM 3144 C CD . ARG B 2 261 ? -44.312 -17.426 0.163 1.00 88.07 ? 431 ARG G CD 1 ATOM 3145 N NE . ARG B 2 261 ? -43.741 -18.653 -0.356 1.00 88.07 ? 431 ARG G NE 1 ATOM 3146 C CZ . ARG B 2 261 ? -43.240 -18.776 -1.562 1.00 88.07 ? 431 ARG G CZ 1 ATOM 3147 N NH1 . ARG B 2 261 ? -43.234 -17.734 -2.355 1.00 88.07 ? 431 ARG G NH1 1 ATOM 3148 N NH2 . ARG B 2 261 ? -42.820 -19.940 -2.018 1.00 88.07 ? 431 ARG G NH2 1 ATOM 3149 N N . ALA B 2 262 ? -49.136 -15.490 1.271 1.00 59.64 ? 432 ALA G N 1 ATOM 3150 C CA . ALA B 2 262 ? -49.872 -14.892 2.370 1.00 59.64 ? 432 ALA G CA 1 ATOM 3151 C C . ALA B 2 262 ? -49.318 -15.563 3.630 1.00 59.64 ? 432 ALA G C 1 ATOM 3152 O O . ALA B 2 262 ? -49.097 -16.790 3.653 1.00 59.64 ? 432 ALA G O 1 ATOM 3153 C CB . ALA B 2 262 ? -51.308 -15.187 2.249 1.00 91.99 ? 432 ALA G CB 1 ATOM 3154 N N . MET B 2 263 ? -49.113 -14.750 4.676 1.00 66.03 ? 433 MET G N 1 ATOM 3155 C CA . MET B 2 263 ? -48.566 -15.195 5.951 1.00 66.03 ? 433 MET G CA 1 ATOM 3156 C C . MET B 2 263 ? -49.675 -14.941 6.985 1.00 66.03 ? 433 MET G C 1 ATOM 3157 O O . MET B 2 263 ? -50.227 -13.849 7.040 1.00 66.03 ? 433 MET G O 1 ATOM 3158 C CB . MET B 2 263 ? -47.304 -14.385 6.312 1.00 161.07 ? 433 MET G CB 1 ATOM 3159 C CG . MET B 2 263 ? -46.675 -14.829 7.630 1.00 161.07 ? 433 MET G CG 1 ATOM 3160 S SD . MET B 2 263 ? -45.226 -13.958 8.306 1.00 161.07 ? 433 MET G SD 1 ATOM 3161 C CE . MET B 2 263 ? -45.875 -12.397 8.803 1.00 161.07 ? 433 MET G CE 1 ATOM 3162 N N . TYR B 2 264 ? -49.972 -15.955 7.803 1.00 107.39 ? 434 TYR G N 1 ATOM 3163 C CA . TYR B 2 264 ? -51.001 -15.992 8.871 1.00 107.39 ? 434 TYR G CA 1 ATOM 3164 C C . TYR B 2 264 ? -50.301 -16.265 10.198 1.00 107.39 ? 434 TYR G C 1 ATOM 3165 O O . TYR B 2 264 ? -49.335 -17.023 10.241 1.00 107.39 ? 434 TYR G O 1 ATOM 3166 C CB . TYR B 2 264 ? -52.096 -17.065 8.688 1.00 76.47 ? 434 TYR G CB 1 ATOM 3167 C CG . TYR B 2 264 ? -53.060 -16.808 7.556 1.00 76.47 ? 434 TYR G CG 1 ATOM 3168 C CD1 . TYR B 2 264 ? -52.810 -17.282 6.284 1.00 76.47 ? 434 TYR G CD1 1 ATOM 3169 C CD2 . TYR B 2 264 ? -54.185 -15.993 7.716 1.00 76.47 ? 434 TYR G CD2 1 ATOM 3170 C CE1 . TYR B 2 264 ? -53.634 -16.965 5.190 1.00 76.47 ? 434 TYR G CE1 1 ATOM 3171 C CE2 . TYR B 2 264 ? -55.033 -15.662 6.603 1.00 76.47 ? 434 TYR G CE2 1 ATOM 3172 C CZ . TYR B 2 264 ? -54.719 -16.163 5.354 1.00 76.47 ? 434 TYR G CZ 1 ATOM 3173 O OH . TYR B 2 264 ? -55.427 -15.830 4.233 1.00 76.47 ? 434 TYR G OH 1 ATOM 3174 N N . ALA B 2 265 ? -50.739 -15.613 11.271 1.00 140.23 ? 435 ALA G N 1 ATOM 3175 C CA . ALA B 2 265 ? -50.088 -15.762 12.585 1.00 140.23 ? 435 ALA G CA 1 ATOM 3176 C C . ALA B 2 265 ? -50.258 -17.162 13.208 1.00 140.23 ? 435 ALA G C 1 ATOM 3177 O O . ALA B 2 265 ? -51.183 -17.899 12.885 1.00 140.23 ? 435 ALA G O 1 ATOM 3178 C CB . ALA B 2 265 ? -50.651 -14.726 13.545 1.00 96.51 ? 435 ALA G CB 1 ATOM 3179 N N . PRO B 2 266 ? -49.372 -17.509 14.165 1.00 163.56 ? 436 PRO G N 1 ATOM 3180 C CA . PRO B 2 266 ? -49.285 -18.772 14.878 1.00 163.56 ? 436 PRO G CA 1 ATOM 3181 C C . PRO B 2 266 ? -50.341 -19.187 15.895 1.00 163.56 ? 436 PRO G C 1 ATOM 3182 O O . PRO B 2 266 ? -51.077 -18.354 16.430 1.00 163.56 ? 436 PRO G O 1 ATOM 3183 C CB . PRO B 2 266 ? -47.899 -18.648 15.444 1.00 75.53 ? 436 PRO G CB 1 ATOM 3184 C CG . PRO B 2 266 ? -48.169 -17.388 16.236 1.00 75.53 ? 436 PRO G CG 1 ATOM 3185 C CD . PRO B 2 266 ? -48.666 -16.511 15.005 1.00 75.53 ? 436 PRO G CD 1 ATOM 3186 N N . PRO B 2 267 ? -50.397 -20.512 16.173 1.00 153.25 ? 437 PRO G N 1 ATOM 3187 C CA . PRO B 2 267 ? -51.286 -21.307 17.068 1.00 153.25 ? 437 PRO G CA 1 ATOM 3188 C C . PRO B 2 267 ? -51.279 -21.368 18.617 1.00 153.25 ? 437 PRO G C 1 ATOM 3189 O O . PRO B 2 267 ? -50.328 -21.856 19.228 1.00 153.25 ? 437 PRO G O 1 ATOM 3190 C CB . PRO B 2 267 ? -51.132 -22.698 16.505 1.00 78.15 ? 437 PRO G CB 1 ATOM 3191 C CG . PRO B 2 267 ? -49.556 -22.689 16.098 1.00 78.15 ? 437 PRO G CG 1 ATOM 3192 C CD . PRO B 2 267 ? -49.378 -21.366 15.476 1.00 78.15 ? 437 PRO G CD 1 ATOM 3193 N N . SER B 2 268 ? -52.348 -20.858 19.232 1.00 153.83 ? 438 SER G N 1 ATOM 3194 C CA . SER B 2 268 ? -52.557 -20.868 20.697 1.00 153.83 ? 438 SER G CA 1 ATOM 3195 C C . SER B 2 268 ? -52.853 -22.191 21.463 1.00 153.83 ? 438 SER G C 1 ATOM 3196 O O . SER B 2 268 ? -52.646 -22.271 22.678 1.00 153.83 ? 438 SER G O 1 ATOM 3197 C CB . SER B 2 268 ? -53.622 -19.822 21.054 1.00 109.18 ? 438 SER G CB 1 ATOM 3198 O OG . SER B 2 268 ? -54.897 -20.219 20.606 1.00 109.18 ? 438 SER G OG 1 ATOM 3199 N N . LYS B 2 269 ? -53.313 -23.226 20.755 1.00 163.15 ? 439 LYS G N 1 ATOM 3200 C CA . LYS B 2 269 ? -53.678 -24.477 21.428 1.00 163.15 ? 439 LYS G CA 1 ATOM 3201 C C . LYS B 2 269 ? -52.818 -25.677 21.000 1.00 163.15 ? 439 LYS G C 1 ATOM 3202 O O . LYS B 2 269 ? -52.418 -25.792 19.839 1.00 163.15 ? 439 LYS G O 1 ATOM 3203 C CB . LYS B 2 269 ? -55.148 -24.792 21.095 1.00 107.92 ? 439 LYS G CB 1 ATOM 3204 C CG . LYS B 2 269 ? -56.100 -23.799 21.688 1.00 107.92 ? 439 LYS G CG 1 ATOM 3205 C CD . LYS B 2 269 ? -57.532 -24.130 21.348 1.00 107.92 ? 439 LYS G CD 1 ATOM 3206 C CE . LYS B 2 269 ? -58.416 -23.068 21.992 1.00 107.92 ? 439 LYS G CE 1 ATOM 3207 N NZ . LYS B 2 269 ? -59.813 -23.137 21.505 1.00 107.92 ? 439 LYS G NZ 1 ATOM 3208 N N . GLY B 2 270 ? -52.457 -26.516 21.972 1.00 161.04 ? 440 GLY G N 1 ATOM 3209 C CA . GLY B 2 270 ? -51.695 -27.719 21.664 1.00 161.04 ? 440 GLY G CA 1 ATOM 3210 C C . GLY B 2 270 ? -52.263 -28.794 20.731 1.00 161.04 ? 440 GLY G C 1 ATOM 3211 O O . GLY B 2 270 ? -51.537 -29.256 19.821 1.00 161.04 ? 440 GLY G O 1 ATOM 3212 N N . ASN B 2 271 ? -53.552 -29.169 20.884 1.00 83.92 ? 441 ASN G N 1 ATOM 3213 C CA . ASN B 2 271 ? -54.036 -30.200 19.990 1.00 83.92 ? 441 ASN G CA 1 ATOM 3214 C C . ASN B 2 271 ? -55.420 -29.903 19.207 1.00 83.92 ? 441 ASN G C 1 ATOM 3215 O O . ASN B 2 271 ? -56.417 -29.490 19.790 1.00 83.92 ? 441 ASN G O 1 ATOM 3216 C CB . ASN B 2 271 ? -53.748 -31.617 20.782 1.00 105.34 ? 441 ASN G CB 1 ATOM 3217 C CG . ASN B 2 271 ? -54.472 -31.844 22.265 1.00 105.34 ? 441 ASN G CG 1 ATOM 3218 O OD1 . ASN B 2 271 ? -55.732 -32.004 22.177 1.00 105.34 ? 441 ASN G OD1 1 ATOM 3219 N ND2 . ASN B 2 271 ? -53.695 -32.003 23.470 1.00 105.34 ? 441 ASN G ND2 1 ATOM 3220 N N . ILE B 2 272 ? -55.435 -30.149 17.872 1.00 132.17 ? 442 ILE G N 1 ATOM 3221 C CA . ILE B 2 272 ? -56.576 -29.933 16.881 1.00 132.17 ? 442 ILE G CA 1 ATOM 3222 C C . ILE B 2 272 ? -57.221 -31.034 16.041 1.00 132.17 ? 442 ILE G C 1 ATOM 3223 O O . ILE B 2 272 ? -56.581 -31.784 15.295 1.00 132.17 ? 442 ILE G O 1 ATOM 3224 C CB . ILE B 2 272 ? -56.499 -28.600 15.938 1.00 108.37 ? 442 ILE G CB 1 ATOM 3225 C CG1 . ILE B 2 272 ? -56.488 -27.329 16.807 1.00 108.37 ? 442 ILE G CG1 1 ATOM 3226 C CG2 . ILE B 2 272 ? -57.519 -28.651 14.816 1.00 108.37 ? 442 ILE G CG2 1 ATOM 3227 C CD1 . ILE B 2 272 ? -56.180 -26.020 16.073 1.00 108.37 ? 442 ILE G CD1 1 ATOM 3228 N N . THR B 2 273 ? -58.546 -31.009 16.137 1.00 201.33 ? 443 THR G N 1 ATOM 3229 C CA . THR B 2 273 ? -59.433 -32.011 15.587 1.00 201.33 ? 443 THR G CA 1 ATOM 3230 C C . THR B 2 273 ? -60.149 -31.760 14.275 1.00 201.33 ? 443 THR G C 1 ATOM 3231 O O . THR B 2 273 ? -60.939 -30.822 14.157 1.00 201.33 ? 443 THR G O 1 ATOM 3232 C CB . THR B 2 273 ? -60.577 -32.183 16.595 1.00 256.06 ? 443 THR G CB 1 ATOM 3233 O OG1 . THR B 2 273 ? -61.768 -32.604 15.918 1.00 256.06 ? 443 THR G OG1 1 ATOM 3234 C CG2 . THR B 2 273 ? -60.883 -30.823 17.266 1.00 256.06 ? 443 THR G CG2 1 ATOM 3235 N N . CYS B 2 274 ? -59.886 -32.628 13.295 1.00 127.66 ? 444 CYS G N 1 ATOM 3236 C CA . CYS B 2 274 ? -60.609 -32.572 12.022 1.00 127.66 ? 444 CYS G CA 1 ATOM 3237 C C . CYS B 2 274 ? -61.222 -33.912 11.653 1.00 127.66 ? 444 CYS G C 1 ATOM 3238 O O . CYS B 2 274 ? -60.556 -34.948 11.708 1.00 127.66 ? 444 CYS G O 1 ATOM 3239 C CB . CYS B 2 274 ? -59.712 -32.064 10.853 1.00 132.96 ? 444 CYS G CB 1 ATOM 3240 S SG . CYS B 2 274 ? -60.517 -31.087 9.522 1.00 132.96 ? 444 CYS G SG 1 ATOM 3241 N N . ILE B 2 275 ? -62.508 -33.874 11.315 1.00 161.65 ? 445 ILE G N 1 ATOM 3242 C CA . ILE B 2 275 ? -63.226 -35.023 10.793 1.00 161.65 ? 445 ILE G CA 1 ATOM 3243 C C . ILE B 2 275 ? -63.696 -34.430 9.477 1.00 161.65 ? 445 ILE G C 1 ATOM 3244 O O . ILE B 2 275 ? -64.221 -33.311 9.418 1.00 161.65 ? 445 ILE G O 1 ATOM 3245 C CB . ILE B 2 275 ? -64.479 -35.460 11.625 1.00 98.61 ? 445 ILE G CB 1 ATOM 3246 C CG1 . ILE B 2 275 ? -65.257 -34.229 12.120 1.00 98.61 ? 445 ILE G CG1 1 ATOM 3247 C CG2 . ILE B 2 275 ? -64.082 -36.401 12.720 1.00 98.61 ? 445 ILE G CG2 1 ATOM 3248 C CD1 . ILE B 2 275 ? -64.824 -33.687 13.494 1.00 98.61 ? 445 ILE G CD1 1 ATOM 3249 N N . SER B 2 276 ? -63.459 -35.154 8.414 1.00 95.81 ? 446 SER G N 1 ATOM 3250 C CA . SER B 2 276 ? -63.878 -34.752 7.091 1.00 95.81 ? 446 SER G CA 1 ATOM 3251 C C . SER B 2 276 ? -64.370 -35.985 6.386 1.00 95.81 ? 446 SER G C 1 ATOM 3252 O O . SER B 2 276 ? -64.003 -37.095 6.763 1.00 95.81 ? 446 SER G O 1 ATOM 3253 C CB . SER B 2 276 ? -62.752 -34.020 6.352 1.00 114.42 ? 446 SER G CB 1 ATOM 3254 O OG . SER B 2 276 ? -62.384 -32.841 7.065 1.00 114.42 ? 446 SER G OG 1 ATOM 3255 N N . ASP B 2 277 ? -65.180 -35.812 5.364 1.00 149.01 ? 447 ASP G N 1 ATOM 3256 C CA . ASP B 2 277 ? -65.753 -36.936 4.653 1.00 149.01 ? 447 ASP G CA 1 ATOM 3257 C C . ASP B 2 277 ? -65.395 -36.675 3.189 1.00 149.01 ? 447 ASP G C 1 ATOM 3258 O O . ASP B 2 277 ? -65.446 -35.530 2.755 1.00 149.01 ? 447 ASP G O 1 ATOM 3259 C CB . ASP B 2 277 ? -67.274 -36.957 4.931 1.00 156.04 ? 447 ASP G CB 1 ATOM 3260 C CG . ASP B 2 277 ? -67.964 -38.227 4.440 1.00 156.04 ? 447 ASP G CG 1 ATOM 3261 O OD1 . ASP B 2 277 ? -67.412 -38.936 3.568 1.00 156.04 ? 447 ASP G OD1 1 ATOM 3262 O OD2 . ASP B 2 277 ? -69.053 -38.531 4.976 1.00 156.04 ? 447 ASP G OD2 1 ATOM 3263 N N . ILE B 2 278 ? -65.031 -37.694 2.408 1.00 118.50 ? 448 ILE G N 1 ATOM 3264 C CA . ILE B 2 278 ? -64.662 -37.366 1.041 1.00 118.50 ? 448 ILE G CA 1 ATOM 3265 C C . ILE B 2 278 ? -65.659 -37.842 0.022 1.00 118.50 ? 448 ILE G C 1 ATOM 3266 O O . ILE B 2 278 ? -66.061 -39.005 -0.017 1.00 118.50 ? 448 ILE G O 1 ATOM 3267 C CB . ILE B 2 278 ? -63.334 -38.072 0.561 1.00 74.36 ? 448 ILE G CB 1 ATOM 3268 C CG1 . ILE B 2 278 ? -62.146 -37.688 1.418 1.00 74.36 ? 448 ILE G CG1 1 ATOM 3269 C CG2 . ILE B 2 278 ? -63.132 -37.894 -0.932 1.00 74.36 ? 448 ILE G CG2 1 ATOM 3270 C CD1 . ILE B 2 278 ? -60.920 -38.528 1.131 1.00 74.36 ? 448 ILE G CD1 1 ATOM 3271 N N . THR B 2 279 ? -66.012 -36.871 -0.830 1.00 97.88 ? 449 THR G N 1 ATOM 3272 C CA . THR B 2 279 ? -66.976 -37.049 -1.905 1.00 97.88 ? 449 THR G CA 1 ATOM 3273 C C . THR B 2 279 ? -66.297 -37.063 -3.273 1.00 97.88 ? 449 THR G C 1 ATOM 3274 O O . THR B 2 279 ? -66.909 -37.460 -4.276 1.00 97.88 ? 449 THR G O 1 ATOM 3275 C CB . THR B 2 279 ? -67.988 -35.852 -1.925 1.00 96.10 ? 449 THR G CB 1 ATOM 3276 O OG1 . THR B 2 279 ? -67.340 -34.650 -2.354 1.00 96.10 ? 449 THR G OG1 1 ATOM 3277 C CG2 . THR B 2 279 ? -68.496 -35.576 -0.496 1.00 96.10 ? 449 THR G CG2 1 ATOM 3278 N N . GLY B 2 280 ? -65.004 -36.704 -3.287 1.00 94.14 ? 450 GLY G N 1 ATOM 3279 C CA . GLY B 2 280 ? -64.277 -36.588 -4.557 1.00 94.14 ? 450 GLY G CA 1 ATOM 3280 C C . GLY B 2 280 ? -62.777 -36.336 -4.764 1.00 94.14 ? 450 GLY G C 1 ATOM 3281 O O . GLY B 2 280 ? -62.001 -36.088 -3.869 1.00 94.14 ? 450 GLY G O 1 ATOM 3282 N N . LEU B 2 281 ? -62.424 -36.390 -6.033 1.00 139.45 ? 451 LEU G N 1 ATOM 3283 C CA . LEU B 2 281 ? -61.064 -36.329 -6.508 1.00 139.45 ? 451 LEU G CA 1 ATOM 3284 C C . LEU B 2 281 ? -60.753 -35.333 -7.624 1.00 139.45 ? 451 LEU G C 1 ATOM 3285 O O . LEU B 2 281 ? -61.655 -34.932 -8.344 1.00 139.45 ? 451 LEU G O 1 ATOM 3286 C CB . LEU B 2 281 ? -60.765 -37.688 -7.083 1.00 94.88 ? 451 LEU G CB 1 ATOM 3287 C CG . LEU B 2 281 ? -60.891 -38.802 -6.091 1.00 94.88 ? 451 LEU G CG 1 ATOM 3288 C CD1 . LEU B 2 281 ? -60.561 -40.073 -6.836 1.00 94.88 ? 451 LEU G CD1 1 ATOM 3289 C CD2 . LEU B 2 281 ? -60.044 -38.546 -4.875 1.00 94.88 ? 451 LEU G CD2 1 ATOM 3290 N N . LEU B 2 282 ? -59.515 -34.862 -7.738 1.00 90.63 ? 452 LEU G N 1 ATOM 3291 C CA . LEU B 2 282 ? -59.193 -34.101 -8.933 1.00 90.63 ? 452 LEU G CA 1 ATOM 3292 C C . LEU B 2 282 ? -58.038 -34.950 -9.572 1.00 90.63 ? 452 LEU G C 1 ATOM 3293 O O . LEU B 2 282 ? -57.140 -35.332 -8.877 1.00 90.63 ? 452 LEU G O 1 ATOM 3294 C CB . LEU B 2 282 ? -58.811 -32.669 -8.539 1.00 84.20 ? 452 LEU G CB 1 ATOM 3295 C CG . LEU B 2 282 ? -59.936 -31.911 -7.798 1.00 84.20 ? 452 LEU G CG 1 ATOM 3296 C CD1 . LEU B 2 282 ? -59.496 -30.532 -7.447 1.00 84.20 ? 452 LEU G CD1 1 ATOM 3297 C CD2 . LEU B 2 282 ? -61.161 -31.822 -8.600 1.00 84.20 ? 452 LEU G CD2 1 ATOM 3298 N N . LEU B 2 283 ? -58.065 -35.286 -10.859 1.00 65.69 ? 453 LEU G N 1 ATOM 3299 C CA . LEU B 2 283 ? -56.991 -36.105 -11.491 1.00 65.69 ? 453 LEU G CA 1 ATOM 3300 C C . LEU B 2 283 ? -56.481 -35.783 -12.894 1.00 65.69 ? 453 LEU G C 1 ATOM 3301 O O . LEU B 2 283 ? -57.247 -35.221 -13.699 1.00 65.69 ? 453 LEU G O 1 ATOM 3302 C CB . LEU B 2 283 ? -57.306 -37.622 -11.467 1.00 66.79 ? 453 LEU G CB 1 ATOM 3303 C CG . LEU B 2 283 ? -57.506 -38.332 -10.125 1.00 66.79 ? 453 LEU G CG 1 ATOM 3304 C CD1 . LEU B 2 283 ? -57.810 -39.815 -10.226 1.00 66.79 ? 453 LEU G CD1 1 ATOM 3305 C CD2 . LEU B 2 283 ? -56.253 -38.137 -9.414 1.00 66.79 ? 453 LEU G CD2 1 ATOM 3306 N N . THR B 2 284 ? -55.222 -36.163 -13.184 1.00 102.79 ? 454 THR G N 1 ATOM 3307 C CA . THR B 2 284 ? -54.547 -35.988 -14.500 1.00 102.79 ? 454 THR G CA 1 ATOM 3308 C C . THR B 2 284 ? -53.701 -37.242 -14.838 1.00 102.79 ? 454 THR G C 1 ATOM 3309 O O . THR B 2 284 ? -53.245 -37.905 -13.905 1.00 102.79 ? 454 THR G O 1 ATOM 3310 C CB . THR B 2 284 ? -53.650 -34.714 -14.534 1.00 90.30 ? 454 THR G CB 1 ATOM 3311 O OG1 . THR B 2 284 ? -53.036 -34.605 -15.816 1.00 90.30 ? 454 THR G OG1 1 ATOM 3312 C CG2 . THR B 2 284 ? -52.586 -34.746 -13.472 1.00 90.30 ? 454 THR G CG2 1 ATOM 3313 N N . ARG B 2 285 ? -53.465 -37.602 -16.115 1.00 77.80 ? 455 ARG G N 1 ATOM 3314 C CA . ARG B 2 285 ? -52.661 -38.834 -16.302 1.00 77.80 ? 455 ARG G CA 1 ATOM 3315 C C . ARG B 2 285 ? -51.663 -38.441 -17.440 1.00 77.80 ? 455 ARG G C 1 ATOM 3316 O O . ARG B 2 285 ? -51.891 -37.525 -18.242 1.00 77.80 ? 455 ARG G O 1 ATOM 3317 C CB . ARG B 2 285 ? -53.418 -40.017 -16.929 1.00 114.08 ? 455 ARG G CB 1 ATOM 3318 C CG . ARG B 2 285 ? -53.763 -39.804 -18.401 1.00 114.08 ? 455 ARG G CG 1 ATOM 3319 C CD . ARG B 2 285 ? -54.513 -40.932 -19.081 1.00 114.08 ? 455 ARG G CD 1 ATOM 3320 N NE . ARG B 2 285 ? -54.511 -40.620 -20.504 1.00 114.08 ? 455 ARG G NE 1 ATOM 3321 C CZ . ARG B 2 285 ? -55.301 -39.779 -21.147 1.00 114.08 ? 455 ARG G CZ 1 ATOM 3322 N NH1 . ARG B 2 285 ? -56.254 -39.104 -20.498 1.00 114.08 ? 455 ARG G NH1 1 ATOM 3323 N NH2 . ARG B 2 285 ? -55.055 -39.575 -22.454 1.00 114.08 ? 455 ARG G NH2 1 ATOM 3324 N N . ASP B 2 286 ? -50.547 -39.143 -17.511 1.00 60.62 ? 456 ASP G N 1 ATOM 3325 C CA . ASP B 2 286 ? -49.541 -38.791 -18.480 1.00 60.62 ? 456 ASP G CA 1 ATOM 3326 C C . ASP B 2 286 ? -49.710 -38.842 -19.943 1.00 60.62 ? 456 ASP G C 1 ATOM 3327 O O . ASP B 2 286 ? -49.338 -37.898 -20.582 1.00 60.62 ? 456 ASP G O 1 ATOM 3328 C CB . ASP B 2 286 ? -48.218 -39.515 -18.132 1.00 113.68 ? 456 ASP G CB 1 ATOM 3329 C CG . ASP B 2 286 ? -47.540 -38.964 -16.854 1.00 113.68 ? 456 ASP G CG 1 ATOM 3330 O OD1 . ASP B 2 286 ? -47.763 -37.784 -16.511 1.00 113.68 ? 456 ASP G OD1 1 ATOM 3331 O OD2 . ASP B 2 286 ? -46.798 -39.703 -16.168 1.00 113.68 ? 456 ASP G OD2 1 ATOM 3332 N N . GLY B 2 287 ? -50.362 -39.832 -20.529 1.00 118.44 ? 457 GLY G N 1 ATOM 3333 C CA . GLY B 2 287 ? -50.332 -39.796 -21.984 1.00 118.44 ? 457 GLY G CA 1 ATOM 3334 C C . GLY B 2 287 ? -48.898 -40.090 -22.449 1.00 118.44 ? 457 GLY G C 1 ATOM 3335 O O . GLY B 2 287 ? -48.354 -41.182 -22.259 1.00 118.44 ? 457 GLY G O 1 ATOM 3336 N N . GLY B 2 288 ? -48.268 -39.070 -23.007 1.00 96.34 ? 458 GLY G N 1 ATOM 3337 C CA . GLY B 2 288 ? -46.926 -39.167 -23.572 1.00 96.34 ? 458 GLY G CA 1 ATOM 3338 C C . GLY B 2 288 ? -46.884 -39.550 -25.062 1.00 96.34 ? 458 GLY G C 1 ATOM 3339 O O . GLY B 2 288 ? -45.853 -39.511 -25.770 1.00 96.34 ? 458 GLY G O 1 ATOM 3340 N N . GLU B 2 289 ? -48.029 -39.934 -25.563 1.00 183.16 ? 459 GLU G N 1 ATOM 3341 C CA . GLU B 2 289 ? -48.164 -40.121 -26.982 1.00 183.16 ? 459 GLU G CA 1 ATOM 3342 C C . GLU B 2 289 ? -47.143 -40.970 -27.776 1.00 183.16 ? 459 GLU G C 1 ATOM 3343 O O . GLU B 2 289 ? -46.719 -40.525 -28.851 1.00 183.16 ? 459 GLU G O 1 ATOM 3344 C CB . GLU B 2 289 ? -48.301 -38.721 -27.603 1.00 136.59 ? 459 GLU G CB 1 ATOM 3345 C CG . GLU B 2 289 ? -49.538 -37.905 -27.086 1.00 136.59 ? 459 GLU G CG 1 ATOM 3346 C CD . GLU B 2 289 ? -50.893 -38.541 -27.339 1.00 136.59 ? 459 GLU G CD 1 ATOM 3347 O OE1 . GLU B 2 289 ? -51.242 -38.774 -28.527 1.00 136.59 ? 459 GLU G OE1 1 ATOM 3348 O OE2 . GLU B 2 289 ? -51.607 -38.794 -26.332 1.00 136.59 ? 459 GLU G OE2 1 ATOM 3349 N N . ASN B 2 290 ? -46.678 -42.102 -27.230 1.00 135.39 ? 460 ASN G N 1 ATOM 3350 C CA . ASN B 2 290 ? -45.828 -43.046 -27.989 1.00 135.39 ? 460 ASN G CA 1 ATOM 3351 C C . ASN B 2 290 ? -44.396 -43.322 -27.407 1.00 135.39 ? 460 ASN G C 1 ATOM 3352 O O . ASN B 2 290 ? -44.236 -43.571 -26.204 1.00 135.39 ? 460 ASN G O 1 ATOM 3353 C CB . ASN B 2 290 ? -45.803 -42.647 -29.493 1.00 131.87 ? 460 ASN G CB 1 ATOM 3354 C CG . ASN B 2 290 ? -45.625 -43.854 -30.449 1.00 131.87 ? 460 ASN G CG 1 ATOM 3355 O OD1 . ASN B 2 290 ? -46.052 -44.981 -30.151 1.00 131.87 ? 460 ASN G OD1 1 ATOM 3356 N ND2 . ASN B 2 290 ? -45.037 -43.601 -31.618 1.00 131.87 ? 460 ASN G ND2 1 ATOM 3357 N N . LYS B 2 291 ? -43.361 -43.179 -28.236 1.00 136.54 ? 461 LYS G N 1 ATOM 3358 C CA . LYS B 2 291 ? -41.975 -43.498 -27.861 1.00 136.54 ? 461 LYS G CA 1 ATOM 3359 C C . LYS B 2 291 ? -41.565 -44.939 -27.424 1.00 136.54 ? 461 LYS G C 1 ATOM 3360 O O . LYS B 2 291 ? -40.848 -45.105 -26.432 1.00 136.54 ? 461 LYS G O 1 ATOM 3361 C CB . LYS B 2 291 ? -41.608 -42.560 -26.717 1.00 100.61 ? 461 LYS G CB 1 ATOM 3362 C CG . LYS B 2 291 ? -40.113 -42.543 -26.311 1.00 100.61 ? 461 LYS G CG 1 ATOM 3363 C CD . LYS B 2 291 ? -39.829 -41.395 -25.333 1.00 100.61 ? 461 LYS G CD 1 ATOM 3364 C CE . LYS B 2 291 ? -40.528 -41.640 -23.996 1.00 100.61 ? 461 LYS G CE 1 ATOM 3365 N NZ . LYS B 2 291 ? -42.025 -41.668 -24.097 1.00 100.61 ? 461 LYS G NZ 1 ATOM 3366 N N . THR B 2 292 ? -42.067 -45.964 -28.130 1.00 277.23 ? 462 THR G N 1 ATOM 3367 C CA . THR B 2 292 ? -41.750 -47.401 -27.903 1.00 277.23 ? 462 THR G CA 1 ATOM 3368 C C . THR B 2 292 ? -41.402 -47.809 -26.460 1.00 277.23 ? 462 THR G C 1 ATOM 3369 O O . THR B 2 292 ? -40.553 -48.667 -26.188 1.00 277.23 ? 462 THR G O 1 ATOM 3370 C CB . THR B 2 292 ? -40.679 -47.954 -28.923 1.00 118.06 ? 462 THR G CB 1 ATOM 3371 O OG1 . THR B 2 292 ? -41.091 -47.634 -30.261 1.00 118.06 ? 462 THR G OG1 1 ATOM 3372 C CG2 . THR B 2 292 ? -40.570 -49.489 -28.836 1.00 118.06 ? 462 THR G CG2 1 ATOM 3373 N N . GLU B 2 293 ? -42.029 -47.074 -25.555 1.00 141.77 ? 463 GLU G N 1 ATOM 3374 C CA . GLU B 2 293 ? -42.053 -47.272 -24.127 1.00 141.77 ? 463 GLU G CA 1 ATOM 3375 C C . GLU B 2 293 ? -42.684 -48.663 -24.146 1.00 141.77 ? 463 GLU G C 1 ATOM 3376 O O . GLU B 2 293 ? -42.348 -49.557 -23.368 1.00 141.77 ? 463 GLU G O 1 ATOM 3377 C CB . GLU B 2 293 ? -42.992 -46.265 -23.513 1.00 128.09 ? 463 GLU G CB 1 ATOM 3378 C CG . GLU B 2 293 ? -42.423 -44.871 -23.593 1.00 128.09 ? 463 GLU G CG 1 ATOM 3379 C CD . GLU B 2 293 ? -41.107 -44.757 -22.864 1.00 128.09 ? 463 GLU G CD 1 ATOM 3380 O OE1 . GLU B 2 293 ? -41.104 -45.019 -21.637 1.00 128.09 ? 463 GLU G OE1 1 ATOM 3381 O OE2 . GLU B 2 293 ? -40.085 -44.380 -23.513 1.00 128.09 ? 463 GLU G OE2 1 ATOM 3382 N N . ASN B 2 294 ? -43.647 -48.742 -25.077 1.00 220.09 ? 464 ASN G N 1 ATOM 3383 C CA . ASN B 2 294 ? -44.601 -49.822 -25.389 1.00 220.09 ? 464 ASN G CA 1 ATOM 3384 C C . ASN B 2 294 ? -45.317 -49.926 -24.092 1.00 220.09 ? 464 ASN G C 1 ATOM 3385 O O . ASN B 2 294 ? -45.721 -51.012 -23.692 1.00 220.09 ? 464 ASN G O 1 ATOM 3386 C CB . ASN B 2 294 ? -43.953 -51.218 -25.623 1.00 134.12 ? 464 ASN G CB 1 ATOM 3387 C CG . ASN B 2 294 ? -42.985 -51.267 -26.794 1.00 134.12 ? 464 ASN G CG 1 ATOM 3388 O OD1 . ASN B 2 294 ? -41.807 -51.578 -26.603 1.00 134.12 ? 464 ASN G OD1 1 ATOM 3389 N ND2 . ASN B 2 294 ? -43.480 -51.006 -28.012 1.00 134.12 ? 464 ASN G ND2 1 ATOM 3390 N N . ASN B 2 295 ? -45.589 -48.781 -23.477 1.00 197.63 ? 465 ASN G N 1 ATOM 3391 C CA . ASN B 2 295 ? -46.245 -48.896 -22.203 1.00 197.63 ? 465 ASN G CA 1 ATOM 3392 C C . ASN B 2 295 ? -47.728 -49.155 -22.351 1.00 197.63 ? 465 ASN G C 1 ATOM 3393 O O . ASN B 2 295 ? -48.427 -48.553 -23.172 1.00 197.63 ? 465 ASN G O 1 ATOM 3394 C CB . ASN B 2 295 ? -46.002 -47.648 -21.313 1.00 120.99 ? 465 ASN G CB 1 ATOM 3395 C CG . ASN B 2 295 ? -46.511 -46.358 -21.938 1.00 120.99 ? 465 ASN G CG 1 ATOM 3396 O OD1 . ASN B 2 295 ? -47.722 -46.136 -22.057 1.00 120.99 ? 465 ASN G OD1 1 ATOM 3397 N ND2 . ASN B 2 295 ? -45.586 -45.487 -22.318 1.00 120.99 ? 465 ASN G ND2 1 ATOM 3398 N N . ASP B 2 296 ? -48.148 -50.166 -21.604 1.00 208.93 ? 466 ASP G N 1 ATOM 3399 C CA . ASP B 2 296 ? -49.534 -50.564 -21.457 1.00 208.93 ? 466 ASP G CA 1 ATOM 3400 C C . ASP B 2 296 ? -50.198 -49.349 -20.850 1.00 208.93 ? 466 ASP G C 1 ATOM 3401 O O . ASP B 2 296 ? -51.309 -48.930 -21.204 1.00 208.93 ? 466 ASP G O 1 ATOM 3402 C CB . ASP B 2 296 ? -49.653 -51.678 -20.412 1.00 142.69 ? 466 ASP G CB 1 ATOM 3403 C CG . ASP B 2 296 ? -49.079 -52.980 -20.865 1.00 142.69 ? 466 ASP G CG 1 ATOM 3404 O OD1 . ASP B 2 296 ? -48.783 -53.811 -19.970 1.00 142.69 ? 466 ASP G OD1 1 ATOM 3405 O OD2 . ASP B 2 296 ? -48.952 -53.176 -22.096 1.00 142.69 ? 466 ASP G OD2 1 ATOM 3406 N N . THR B 2 297 ? -49.413 -48.789 -19.933 1.00 165.22 ? 467 THR G N 1 ATOM 3407 C CA . THR B 2 297 ? -49.805 -47.745 -19.016 1.00 165.22 ? 467 THR G CA 1 ATOM 3408 C C . THR B 2 297 ? -50.138 -46.281 -19.176 1.00 165.22 ? 467 THR G C 1 ATOM 3409 O O . THR B 2 297 ? -49.690 -45.565 -20.066 1.00 165.22 ? 467 THR G O 1 ATOM 3410 C CB . THR B 2 297 ? -48.729 -47.710 -17.893 1.00 98.61 ? 467 THR G CB 1 ATOM 3411 O OG1 . THR B 2 297 ? -47.420 -47.525 -18.483 1.00 98.61 ? 467 THR G OG1 1 ATOM 3412 C CG2 . THR B 2 297 ? -48.772 -48.976 -17.047 1.00 98.61 ? 467 THR G CG2 1 ATOM 3413 N N . GLU B 2 298 ? -51.018 -45.916 -18.246 1.00 145.19 ? 468 GLU G N 1 ATOM 3414 C CA . GLU B 2 298 ? -51.423 -44.576 -17.901 1.00 145.19 ? 468 GLU G CA 1 ATOM 3415 C C . GLU B 2 298 ? -51.144 -44.438 -16.420 1.00 145.19 ? 468 GLU G C 1 ATOM 3416 O O . GLU B 2 298 ? -51.383 -45.345 -15.606 1.00 145.19 ? 468 GLU G O 1 ATOM 3417 C CB . GLU B 2 298 ? -52.863 -44.256 -18.278 1.00 192.29 ? 468 GLU G CB 1 ATOM 3418 C CG . GLU B 2 298 ? -53.023 -44.158 -19.774 1.00 192.29 ? 468 GLU G CG 1 ATOM 3419 C CD . GLU B 2 298 ? -53.029 -45.480 -20.477 1.00 192.29 ? 468 GLU G CD 1 ATOM 3420 O OE1 . GLU B 2 298 ? -53.096 -46.517 -19.801 1.00 192.29 ? 468 GLU G OE1 1 ATOM 3421 O OE2 . GLU B 2 298 ? -52.954 -45.481 -21.721 1.00 192.29 ? 468 GLU G OE2 1 ATOM 3422 N N . ILE B 2 299 ? -50.652 -43.275 -16.072 1.00 115.93 ? 469 ILE G N 1 ATOM 3423 C CA . ILE B 2 299 ? -50.321 -42.998 -14.705 1.00 115.93 ? 469 ILE G CA 1 ATOM 3424 C C . ILE B 2 299 ? -51.224 -41.810 -14.415 1.00 115.93 ? 469 ILE G C 1 ATOM 3425 O O . ILE B 2 299 ? -51.256 -40.839 -15.173 1.00 115.93 ? 469 ILE G O 1 ATOM 3426 C CB . ILE B 2 299 ? -48.761 -42.674 -14.506 1.00 125.54 ? 469 ILE G CB 1 ATOM 3427 C CG1 . ILE B 2 299 ? -47.885 -43.855 -14.949 1.00 125.54 ? 469 ILE G CG1 1 ATOM 3428 C CG2 . ILE B 2 299 ? -48.450 -42.380 -13.051 1.00 125.54 ? 469 ILE G CG2 1 ATOM 3429 C CD1 . ILE B 2 299 ? -46.406 -43.539 -15.017 1.00 125.54 ? 469 ILE G CD1 1 ATOM 3430 N N . PHE B 2 300 ? -51.960 -41.889 -13.316 1.00 117.50 ? 470 PHE G N 1 ATOM 3431 C CA . PHE B 2 300 ? -52.836 -40.800 -12.944 1.00 117.50 ? 470 PHE G CA 1 ATOM 3432 C C . PHE B 2 300 ? -52.246 -40.430 -11.605 1.00 117.50 ? 470 PHE G C 1 ATOM 3433 O O . PHE B 2 300 ? -51.895 -41.275 -10.768 1.00 117.50 ? 470 PHE G O 1 ATOM 3434 C CB . PHE B 2 300 ? -54.270 -41.323 -12.786 1.00 138.23 ? 470 PHE G CB 1 ATOM 3435 C CG . PHE B 2 300 ? -54.956 -41.734 -14.082 1.00 138.23 ? 470 PHE G CG 1 ATOM 3436 C CD1 . PHE B 2 300 ? -55.697 -40.810 -14.812 1.00 138.23 ? 470 PHE G CD1 1 ATOM 3437 C CD2 . PHE B 2 300 ? -54.800 -43.004 -14.623 1.00 138.23 ? 470 PHE G CD2 1 ATOM 3438 C CE1 . PHE B 2 300 ? -56.286 -41.150 -16.046 1.00 138.23 ? 470 PHE G CE1 1 ATOM 3439 C CE2 . PHE B 2 300 ? -55.386 -43.347 -15.877 1.00 138.23 ? 470 PHE G CE2 1 ATOM 3440 C CZ . PHE B 2 300 ? -56.129 -42.415 -16.573 1.00 138.23 ? 470 PHE G CZ 1 ATOM 3441 N N . ARG B 2 301 ? -52.208 -39.119 -11.416 1.00 125.71 ? 471 ARG G N 1 ATOM 3442 C CA . ARG B 2 301 ? -51.587 -38.522 -10.270 1.00 125.71 ? 471 ARG G CA 1 ATOM 3443 C C . ARG B 2 301 ? -52.599 -37.580 -9.694 1.00 125.71 ? 471 ARG G C 1 ATOM 3444 O O . ARG B 2 301 ? -53.373 -36.990 -10.445 1.00 125.71 ? 471 ARG G O 1 ATOM 3445 C CB . ARG B 2 301 ? -50.435 -37.708 -10.812 1.00 85.82 ? 471 ARG G CB 1 ATOM 3446 C CG . ARG B 2 301 ? -49.426 -38.535 -11.563 1.00 85.82 ? 471 ARG G CG 1 ATOM 3447 C CD . ARG B 2 301 ? -48.594 -37.691 -12.484 1.00 85.82 ? 471 ARG G CD 1 ATOM 3448 N NE . ARG B 2 301 ? -47.763 -38.539 -13.332 1.00 85.82 ? 471 ARG G NE 1 ATOM 3449 C CZ . ARG B 2 301 ? -46.871 -39.422 -12.875 1.00 85.82 ? 471 ARG G CZ 1 ATOM 3450 N NH1 . ARG B 2 301 ? -46.674 -39.576 -11.555 1.00 85.82 ? 471 ARG G NH1 1 ATOM 3451 N NH2 . ARG B 2 301 ? -46.202 -40.175 -13.751 1.00 85.82 ? 471 ARG G NH2 1 ATOM 3452 N N . PRO B 2 302 ? -52.574 -37.360 -8.371 1.00 122.98 ? 472 PRO G N 1 ATOM 3453 C CA . PRO B 2 302 ? -53.620 -36.416 -8.009 1.00 122.98 ? 472 PRO G CA 1 ATOM 3454 C C . PRO B 2 302 ? -53.418 -35.059 -8.704 1.00 122.98 ? 472 PRO G C 1 ATOM 3455 O O . PRO B 2 302 ? -52.525 -34.885 -9.546 1.00 122.98 ? 472 PRO G O 1 ATOM 3456 C CB . PRO B 2 302 ? -53.568 -36.388 -6.455 1.00 50.45 ? 472 PRO G CB 1 ATOM 3457 C CG . PRO B 2 302 ? -52.395 -37.305 -6.033 1.00 50.45 ? 472 PRO G CG 1 ATOM 3458 C CD . PRO B 2 302 ? -52.224 -38.225 -7.227 1.00 50.45 ? 472 PRO G CD 1 ATOM 3459 N N . GLY B 2 303 ? -54.248 -34.099 -8.335 1.00 92.49 ? 473 GLY G N 1 ATOM 3460 C CA . GLY B 2 303 ? -54.196 -32.779 -8.940 1.00 92.49 ? 473 GLY G CA 1 ATOM 3461 C C . GLY B 2 303 ? -55.038 -31.756 -8.174 1.00 92.49 ? 473 GLY G C 1 ATOM 3462 O O . GLY B 2 303 ? -55.483 -31.997 -7.026 1.00 92.49 ? 473 GLY G O 1 ATOM 3463 N N . GLY B 2 304 ? -55.178 -30.579 -8.764 1.00 123.56 ? 474 GLY G N 1 ATOM 3464 C CA . GLY B 2 304 ? -55.939 -29.554 -8.106 1.00 123.56 ? 474 GLY G CA 1 ATOM 3465 C C . GLY B 2 304 ? -55.320 -28.202 -8.365 1.00 123.56 ? 474 GLY G C 1 ATOM 3466 O O . GLY B 2 304 ? -54.569 -28.024 -9.309 1.00 123.56 ? 474 GLY G O 1 ATOM 3467 N N . GLY B 2 305 ? -55.686 -27.245 -7.516 1.00 91.92 ? 475 GLY G N 1 ATOM 3468 C CA . GLY B 2 305 ? -55.197 -25.866 -7.545 1.00 91.92 ? 475 GLY G CA 1 ATOM 3469 C C . GLY B 2 305 ? -55.976 -24.857 -8.383 1.00 91.92 ? 475 GLY G C 1 ATOM 3470 O O . GLY B 2 305 ? -55.800 -23.639 -8.204 1.00 91.92 ? 475 GLY G O 1 ATOM 3471 N N . ASP B 2 306 ? -56.925 -25.335 -9.194 1.00 116.53 ? 476 ASP G N 1 ATOM 3472 C CA . ASP B 2 306 ? -57.742 -24.390 -9.917 1.00 116.53 ? 476 ASP G CA 1 ATOM 3473 C C . ASP B 2 306 ? -58.926 -24.599 -8.995 1.00 116.53 ? 476 ASP G C 1 ATOM 3474 O O . ASP B 2 306 ? -59.571 -25.650 -8.970 1.00 116.53 ? 476 ASP G O 1 ATOM 3475 C CB . ASP B 2 306 ? -58.093 -24.851 -11.345 1.00 113.38 ? 476 ASP G CB 1 ATOM 3476 C CG . ASP B 2 306 ? -58.774 -23.731 -12.184 1.00 113.38 ? 476 ASP G CG 1 ATOM 3477 O OD1 . ASP B 2 306 ? -59.301 -22.773 -11.577 1.00 113.38 ? 476 ASP G OD1 1 ATOM 3478 O OD2 . ASP B 2 306 ? -58.782 -23.799 -13.443 1.00 113.38 ? 476 ASP G OD2 1 ATOM 3479 N N . MET B 2 307 ? -59.176 -23.563 -8.231 1.00 98.57 ? 477 MET G N 1 ATOM 3480 C CA . MET B 2 307 ? -60.246 -23.440 -7.235 1.00 98.57 ? 477 MET G CA 1 ATOM 3481 C C . MET B 2 307 ? -61.666 -23.587 -7.819 1.00 98.57 ? 477 MET G C 1 ATOM 3482 O O . MET B 2 307 ? -62.576 -24.155 -7.203 1.00 98.57 ? 477 MET G O 1 ATOM 3483 C CB . MET B 2 307 ? -59.995 -22.245 -6.310 1.00 85.55 ? 477 MET G CB 1 ATOM 3484 C CG . MET B 2 307 ? -58.729 -22.672 -5.461 1.00 85.55 ? 477 MET G CG 1 ATOM 3485 S SD . MET B 2 307 ? -58.787 -24.194 -4.383 1.00 85.55 ? 477 MET G SD 1 ATOM 3486 C CE . MET B 2 307 ? -57.316 -25.014 -4.923 1.00 85.55 ? 477 MET G CE 1 ATOM 3487 N N . LYS B 2 308 ? -61.809 -23.040 -9.019 1.00 106.73 ? 478 LYS G N 1 ATOM 3488 C CA . LYS B 2 308 ? -63.007 -22.971 -9.833 1.00 106.73 ? 478 LYS G CA 1 ATOM 3489 C C . LYS B 2 308 ? -63.369 -24.496 -10.052 1.00 106.73 ? 478 LYS G C 1 ATOM 3490 O O . LYS B 2 308 ? -64.561 -24.822 -10.018 1.00 106.73 ? 478 LYS G O 1 ATOM 3491 C CB . LYS B 2 308 ? -62.713 -22.203 -11.139 1.00 90.64 ? 478 LYS G CB 1 ATOM 3492 C CG . LYS B 2 308 ? -62.464 -20.669 -10.974 1.00 90.64 ? 478 LYS G CG 1 ATOM 3493 C CD . LYS B 2 308 ? -62.183 -19.956 -12.345 1.00 90.64 ? 478 LYS G CD 1 ATOM 3494 C CE . LYS B 2 308 ? -61.939 -18.451 -12.186 1.00 90.64 ? 478 LYS G CE 1 ATOM 3495 N NZ . LYS B 2 308 ? -63.154 -17.747 -11.657 1.00 90.64 ? 478 LYS G NZ 1 ATOM 3496 N N . ASP B 2 309 ? -62.440 -25.436 -10.281 1.00 76.34 ? 479 ASP G N 1 ATOM 3497 C CA . ASP B 2 309 ? -62.892 -26.857 -10.403 1.00 76.34 ? 479 ASP G CA 1 ATOM 3498 C C . ASP B 2 309 ? -63.607 -27.378 -9.118 1.00 76.34 ? 479 ASP G C 1 ATOM 3499 O O . ASP B 2 309 ? -64.600 -28.078 -9.236 1.00 76.34 ? 479 ASP G O 1 ATOM 3500 C CB . ASP B 2 309 ? -61.727 -27.806 -10.721 1.00 94.33 ? 479 ASP G CB 1 ATOM 3501 C CG . ASP B 2 309 ? -61.216 -27.613 -12.090 1.00 94.33 ? 479 ASP G CG 1 ATOM 3502 O OD1 . ASP B 2 309 ? -62.019 -27.082 -12.872 1.00 94.33 ? 479 ASP G OD1 1 ATOM 3503 O OD2 . ASP B 2 309 ? -60.065 -27.983 -12.390 1.00 94.33 ? 479 ASP G OD2 1 ATOM 3504 N N . ASN B 2 310 ? -63.148 -27.049 -7.919 1.00 93.38 ? 480 ASN G N 1 ATOM 3505 C CA . ASN B 2 310 ? -63.865 -27.462 -6.699 1.00 93.38 ? 480 ASN G CA 1 ATOM 3506 C C . ASN B 2 310 ? -65.217 -26.862 -6.788 1.00 93.38 ? 480 ASN G C 1 ATOM 3507 O O . ASN B 2 310 ? -66.167 -27.484 -6.427 1.00 93.38 ? 480 ASN G O 1 ATOM 3508 C CB . ASN B 2 310 ? -63.270 -26.895 -5.408 1.00 147.25 ? 480 ASN G CB 1 ATOM 3509 C CG . ASN B 2 310 ? -61.957 -27.489 -5.071 1.00 147.25 ? 480 ASN G CG 1 ATOM 3510 O OD1 . ASN B 2 310 ? -60.898 -26.969 -5.429 1.00 147.25 ? 480 ASN G OD1 1 ATOM 3511 N ND2 . ASN B 2 310 ? -62.009 -28.578 -4.323 1.00 147.25 ? 480 ASN G ND2 1 ATOM 3512 N N . TRP B 2 311 ? -65.280 -25.642 -7.257 1.00 144.50 ? 481 TRP G N 1 ATOM 3513 C CA . TRP B 2 311 ? -66.516 -24.924 -7.291 1.00 144.50 ? 481 TRP G CA 1 ATOM 3514 C C . TRP B 2 311 ? -67.358 -25.653 -8.362 1.00 144.50 ? 481 TRP G C 1 ATOM 3515 O O . TRP B 2 311 ? -68.578 -25.781 -8.225 1.00 144.50 ? 481 TRP G O 1 ATOM 3516 C CB . TRP B 2 311 ? -66.219 -23.514 -7.706 1.00 100.50 ? 481 TRP G CB 1 ATOM 3517 C CG . TRP B 2 311 ? -65.466 -22.844 -6.644 1.00 100.50 ? 481 TRP G CG 1 ATOM 3518 C CD1 . TRP B 2 311 ? -64.396 -22.028 -6.833 1.00 100.50 ? 481 TRP G CD1 1 ATOM 3519 C CD2 . TRP B 2 311 ? -65.422 -23.215 -5.257 1.00 100.50 ? 481 TRP G CD2 1 ATOM 3520 N NE1 . TRP B 2 311 ? -63.706 -21.870 -5.682 1.00 100.50 ? 481 TRP G NE1 1 ATOM 3521 C CE2 . TRP B 2 311 ? -64.313 -22.583 -4.693 1.00 100.50 ? 481 TRP G CE2 1 ATOM 3522 C CE3 . TRP B 2 311 ? -66.209 -24.025 -4.444 1.00 100.50 ? 481 TRP G CE3 1 ATOM 3523 C CZ2 . TRP B 2 311 ? -63.974 -22.721 -3.359 1.00 100.50 ? 481 TRP G CZ2 1 ATOM 3524 C CZ3 . TRP B 2 311 ? -65.858 -24.168 -3.102 1.00 100.50 ? 481 TRP G CZ3 1 ATOM 3525 C CH2 . TRP B 2 311 ? -64.758 -23.518 -2.582 1.00 100.50 ? 481 TRP G CH2 1 ATOM 3526 N N . ARG B 2 312 ? -66.725 -26.060 -9.459 1.00 104.20 ? 482 ARG G N 1 ATOM 3527 C CA . ARG B 2 312 ? -67.403 -26.827 -10.490 1.00 104.20 ? 482 ARG G CA 1 ATOM 3528 C C . ARG B 2 312 ? -68.013 -28.165 -10.139 1.00 104.20 ? 482 ARG G C 1 ATOM 3529 O O . ARG B 2 312 ? -69.047 -28.499 -10.696 1.00 104.20 ? 482 ARG G O 1 ATOM 3530 C CB . ARG B 2 312 ? -66.714 -26.771 -11.842 1.00 80.39 ? 482 ARG G CB 1 ATOM 3531 C CG . ARG B 2 312 ? -66.943 -25.344 -12.303 1.00 80.39 ? 482 ARG G CG 1 ATOM 3532 C CD . ARG B 2 312 ? -66.386 -24.977 -13.600 1.00 80.39 ? 482 ARG G CD 1 ATOM 3533 N NE . ARG B 2 312 ? -64.955 -25.127 -13.647 1.00 80.39 ? 482 ARG G NE 1 ATOM 3534 C CZ . ARG B 2 312 ? -64.282 -25.217 -14.788 1.00 80.39 ? 482 ARG G CZ 1 ATOM 3535 N NH1 . ARG B 2 312 ? -64.939 -25.188 -15.944 1.00 80.39 ? 482 ARG G NH1 1 ATOM 3536 N NH2 . ARG B 2 312 ? -62.962 -25.291 -14.790 1.00 80.39 ? 482 ARG G NH2 1 ATOM 3537 N N . SER B 2 313 ? -67.371 -28.997 -9.316 1.00 106.37 ? 483 SER G N 1 ATOM 3538 C CA . SER B 2 313 ? -68.036 -30.277 -9.015 1.00 106.37 ? 483 SER G CA 1 ATOM 3539 C C . SER B 2 313 ? -69.438 -30.116 -8.335 1.00 106.37 ? 483 SER G C 1 ATOM 3540 O O . SER B 2 313 ? -70.351 -30.828 -8.701 1.00 106.37 ? 483 SER G O 1 ATOM 3541 C CB . SER B 2 313 ? -67.109 -31.135 -8.111 1.00 133.50 ? 483 SER G CB 1 ATOM 3542 O OG . SER B 2 313 ? -66.851 -30.519 -6.853 1.00 133.50 ? 483 SER G OG 1 ATOM 3543 N N . GLU B 2 314 ? -69.640 -29.187 -7.407 1.00 202.88 ? 484 GLU G N 1 ATOM 3544 C CA . GLU B 2 314 ? -70.976 -28.916 -6.856 1.00 202.88 ? 484 GLU G CA 1 ATOM 3545 C C . GLU B 2 314 ? -71.991 -28.262 -7.789 1.00 202.88 ? 484 GLU G C 1 ATOM 3546 O O . GLU B 2 314 ? -73.179 -28.510 -7.714 1.00 202.88 ? 484 GLU G O 1 ATOM 3547 C CB . GLU B 2 314 ? -71.037 -28.280 -5.471 1.00 135.45 ? 484 GLU G CB 1 ATOM 3548 C CG . GLU B 2 314 ? -70.587 -29.268 -4.387 1.00 135.45 ? 484 GLU G CG 1 ATOM 3549 C CD . GLU B 2 314 ? -70.631 -28.673 -2.995 1.00 135.45 ? 484 GLU G CD 1 ATOM 3550 O OE1 . GLU B 2 314 ? -70.969 -27.474 -2.882 1.00 135.45 ? 484 GLU G OE1 1 ATOM 3551 O OE2 . GLU B 2 314 ? -70.344 -29.407 -2.019 1.00 135.45 ? 484 GLU G OE2 1 ATOM 3552 N N . LEU B 2 315 ? -71.496 -27.317 -8.578 1.00 70.19 ? 485 LEU G N 1 ATOM 3553 C CA . LEU B 2 315 ? -72.252 -26.487 -9.502 1.00 70.19 ? 485 LEU G CA 1 ATOM 3554 C C . LEU B 2 315 ? -72.428 -26.991 -10.911 1.00 70.19 ? 485 LEU G C 1 ATOM 3555 O O . LEU B 2 315 ? -73.047 -26.288 -11.663 1.00 70.19 ? 485 LEU G O 1 ATOM 3556 C CB . LEU B 2 315 ? -71.623 -25.112 -9.631 1.00 68.24 ? 485 LEU G CB 1 ATOM 3557 C CG . LEU B 2 315 ? -71.537 -24.329 -8.358 1.00 68.24 ? 485 LEU G CG 1 ATOM 3558 C CD1 . LEU B 2 315 ? -70.890 -22.995 -8.598 1.00 68.24 ? 485 LEU G CD1 1 ATOM 3559 C CD2 . LEU B 2 315 ? -72.930 -24.144 -7.855 1.00 68.24 ? 485 LEU G CD2 1 ATOM 3560 N N . TYR B 2 316 ? -71.919 -28.150 -11.311 1.00 96.61 ? 486 TYR G N 1 ATOM 3561 C CA . TYR B 2 316 ? -72.044 -28.516 -12.730 1.00 96.61 ? 486 TYR G CA 1 ATOM 3562 C C . TYR B 2 316 ? -73.471 -28.640 -13.314 1.00 96.61 ? 486 TYR G C 1 ATOM 3563 O O . TYR B 2 316 ? -73.707 -28.224 -14.476 1.00 96.61 ? 486 TYR G O 1 ATOM 3564 C CB . TYR B 2 316 ? -71.312 -29.843 -12.911 1.00 114.04 ? 486 TYR G CB 1 ATOM 3565 C CG . TYR B 2 316 ? -71.956 -31.066 -12.283 1.00 114.04 ? 486 TYR G CG 1 ATOM 3566 C CD1 . TYR B 2 316 ? -72.868 -31.837 -13.008 1.00 114.04 ? 486 TYR G CD1 1 ATOM 3567 C CD2 . TYR B 2 316 ? -71.652 -31.458 -10.987 1.00 114.04 ? 486 TYR G CD2 1 ATOM 3568 C CE1 . TYR B 2 316 ? -73.447 -32.975 -12.468 1.00 114.04 ? 486 TYR G CE1 1 ATOM 3569 C CE2 . TYR B 2 316 ? -72.233 -32.600 -10.427 1.00 114.04 ? 486 TYR G CE2 1 ATOM 3570 C CZ . TYR B 2 316 ? -73.124 -33.356 -11.174 1.00 114.04 ? 486 TYR G CZ 1 ATOM 3571 O OH . TYR B 2 316 ? -73.667 -34.500 -10.629 1.00 114.04 ? 486 TYR G OH 1 ATOM 3572 N N . LYS B 2 317 ? -74.393 -29.213 -12.535 1.00 110.27 ? 487 LYS G N 1 ATOM 3573 C CA . LYS B 2 317 ? -75.798 -29.272 -12.903 1.00 110.27 ? 487 LYS G CA 1 ATOM 3574 C C . LYS B 2 317 ? -76.462 -27.906 -13.088 1.00 110.27 ? 487 LYS G C 1 ATOM 3575 O O . LYS B 2 317 ? -77.203 -27.717 -14.037 1.00 110.27 ? 487 LYS G O 1 ATOM 3576 C CB . LYS B 2 317 ? -76.536 -30.108 -11.869 1.00 71.31 ? 487 LYS G CB 1 ATOM 3577 C CG . LYS B 2 317 ? -76.640 -29.410 -10.518 1.00 71.31 ? 487 LYS G CG 1 ATOM 3578 C CD . LYS B 2 317 ? -77.167 -30.375 -9.445 1.00 71.31 ? 487 LYS G CD 1 ATOM 3579 C CE . LYS B 2 317 ? -77.491 -29.680 -8.140 1.00 71.31 ? 487 LYS G CE 1 ATOM 3580 N NZ . LYS B 2 317 ? -76.716 -30.356 -7.000 1.00 71.31 ? 487 LYS G NZ 1 ATOM 3581 N N . TYR B 2 318 ? -76.142 -26.938 -12.227 1.00 81.40 ? 488 TYR G N 1 ATOM 3582 C CA . TYR B 2 318 ? -76.735 -25.611 -12.341 1.00 81.40 ? 488 TYR G CA 1 ATOM 3583 C C . TYR B 2 318 ? -76.316 -24.715 -13.542 1.00 81.40 ? 488 TYR G C 1 ATOM 3584 O O . TYR B 2 318 ? -75.166 -24.589 -13.852 1.00 81.40 ? 488 TYR G O 1 ATOM 3585 C CB . TYR B 2 318 ? -76.480 -24.836 -11.046 1.00 80.20 ? 488 TYR G CB 1 ATOM 3586 C CG . TYR B 2 318 ? -77.037 -25.419 -9.733 1.00 80.20 ? 488 TYR G CG 1 ATOM 3587 C CD1 . TYR B 2 318 ? -76.284 -25.365 -8.557 1.00 80.20 ? 488 TYR G CD1 1 ATOM 3588 C CD2 . TYR B 2 318 ? -78.317 -25.935 -9.650 1.00 80.20 ? 488 TYR G CD2 1 ATOM 3589 C CE1 . TYR B 2 318 ? -76.783 -25.783 -7.365 1.00 80.20 ? 488 TYR G CE1 1 ATOM 3590 C CE2 . TYR B 2 318 ? -78.818 -26.366 -8.440 1.00 80.20 ? 488 TYR G CE2 1 ATOM 3591 C CZ . TYR B 2 318 ? -78.035 -26.273 -7.310 1.00 80.20 ? 488 TYR G CZ 1 ATOM 3592 O OH . TYR B 2 318 ? -78.502 -26.622 -6.093 1.00 80.20 ? 488 TYR G OH 1 ATOM 3593 N N . LYS B 2 319 ? -77.262 -24.002 -14.131 1.00 131.45 ? 489 LYS G N 1 ATOM 3594 C CA . LYS B 2 319 ? -77.065 -23.098 -15.278 1.00 131.45 ? 489 LYS G CA 1 ATOM 3595 C C . LYS B 2 319 ? -77.844 -21.794 -15.184 1.00 131.45 ? 489 LYS G C 1 ATOM 3596 O O . LYS B 2 319 ? -78.967 -21.793 -14.721 1.00 131.45 ? 489 LYS G O 1 ATOM 3597 C CB . LYS B 2 319 ? -77.401 -23.774 -16.634 1.00 89.12 ? 489 LYS G CB 1 ATOM 3598 C CG . LYS B 2 319 ? -77.186 -22.804 -17.796 1.00 89.12 ? 489 LYS G CG 1 ATOM 3599 C CD . LYS B 2 319 ? -77.485 -23.337 -19.154 1.00 89.12 ? 489 LYS G CD 1 ATOM 3600 C CE . LYS B 2 319 ? -77.211 -22.228 -20.174 1.00 89.12 ? 489 LYS G CE 1 ATOM 3601 N NZ . LYS B 2 319 ? -77.999 -22.419 -21.474 1.00 89.12 ? 489 LYS G NZ 1 ATOM 3602 N N . VAL B 2 320 ? -77.274 -20.674 -15.578 1.00 75.05 ? 490 VAL G N 1 ATOM 3603 C CA . VAL B 2 320 ? -78.059 -19.459 -15.548 1.00 75.05 ? 490 VAL G CA 1 ATOM 3604 C C . VAL B 2 320 ? -78.436 -18.898 -16.899 1.00 75.05 ? 490 VAL G C 1 ATOM 3605 O O . VAL B 2 320 ? -77.564 -18.647 -17.723 1.00 75.05 ? 490 VAL G O 1 ATOM 3606 C CB . VAL B 2 320 ? -77.402 -18.342 -14.730 1.00 75.64 ? 490 VAL G CB 1 ATOM 3607 C CG1 . VAL B 2 320 ? -78.282 -17.107 -14.746 1.00 75.64 ? 490 VAL G CG1 1 ATOM 3608 C CG2 . VAL B 2 320 ? -77.333 -18.760 -13.263 1.00 75.64 ? 490 VAL G CG2 1 ATOM 3609 N N . VAL B 2 321 ? -79.768 -18.794 -17.118 1.00 71.31 ? 491 VAL G N 1 ATOM 3610 C CA . VAL B 2 321 ? -80.483 -18.250 -18.332 1.00 71.31 ? 491 VAL G CA 1 ATOM 3611 C C . VAL B 2 321 ? -81.718 -17.406 -18.018 1.00 71.31 ? 491 VAL G C 1 ATOM 3612 O O . VAL B 2 321 ? -82.092 -17.254 -16.847 1.00 71.31 ? 491 VAL G O 1 ATOM 3613 C CB . VAL B 2 321 ? -80.935 -19.298 -19.395 1.00 59.93 ? 491 VAL G CB 1 ATOM 3614 C CG1 . VAL B 2 321 ? -79.739 -19.904 -20.123 1.00 59.93 ? 491 VAL G CG1 1 ATOM 3615 C CG2 . VAL B 2 321 ? -81.812 -20.346 -18.706 1.00 59.93 ? 491 VAL G CG2 1 ATOM 3616 N N . GLU B 2 322 ? -82.227 -16.755 -19.069 1.00 163.09 ? 492 GLU G N 1 ATOM 3617 C CA . GLU B 2 322 ? -83.491 -16.012 -19.012 1.00 163.09 ? 492 GLU G CA 1 ATOM 3618 C C . GLU B 2 322 ? -84.227 -16.418 -20.320 1.00 163.09 ? 492 GLU G C 1 ATOM 3619 O O . GLU B 2 322 ? -83.570 -16.903 -21.264 1.00 163.09 ? 492 GLU G O 1 ATOM 3620 C CB . GLU B 2 322 ? -83.322 -14.481 -18.921 1.00 117.65 ? 492 GLU G CB 1 ATOM 3621 C CG . GLU B 2 322 ? -82.638 -13.767 -20.086 1.00 117.65 ? 492 GLU G CG 1 ATOM 3622 C CD . GLU B 2 322 ? -82.537 -12.255 -19.867 1.00 117.65 ? 492 GLU G CD 1 ATOM 3623 O OE1 . GLU B 2 322 ? -81.731 -11.574 -20.536 1.00 117.65 ? 492 GLU G OE1 1 ATOM 3624 O OE2 . GLU B 2 322 ? -83.317 -11.742 -19.046 1.00 117.65 ? 492 GLU G OE2 1 ATOM 3625 N N . ILE B 2 323 ? -85.566 -16.235 -20.356 1.00 215.15 ? 493 ILE G N 1 ATOM 3626 C CA . ILE B 2 323 ? -86.468 -16.667 -21.472 1.00 215.15 ? 493 ILE G CA 1 ATOM 3627 C C . ILE B 2 323 ? -86.002 -17.897 -22.309 1.00 215.15 ? 493 ILE G C 1 ATOM 3628 O O . ILE B 2 323 ? -86.867 -18.795 -22.473 1.00 215.15 ? 493 ILE G O 1 ATOM 3629 C CB . ILE B 2 323 ? -86.975 -15.458 -22.447 1.00 72.28 ? 493 ILE G CB 1 ATOM 3630 C CG1 . ILE B 2 323 ? -87.774 -14.401 -21.651 1.00 72.28 ? 493 ILE G CG1 1 ATOM 3631 C CG2 . ILE B 2 323 ? -87.840 -16.022 -23.620 1.00 72.28 ? 493 ILE G CG2 1 ATOM 3632 C CD1 . ILE B 2 323 ? -88.069 -13.133 -22.444 1.00 72.28 ? 493 ILE G CD1 1 ATOM 3633 N N . GLN C 3 1 ? -30.125 6.299 3.632 1.00 19.21 ? 1 GLN H N 1 ATOM 3634 C CA . GLN C 3 1 ? -30.497 5.358 4.616 1.00 19.21 ? 1 GLN H CA 1 ATOM 3635 C C . GLN C 3 1 ? -31.323 4.166 4.352 1.00 19.21 ? 1 GLN H C 1 ATOM 3636 O O . GLN C 3 1 ? -32.248 4.306 3.601 1.00 19.21 ? 1 GLN H O 1 ATOM 3637 C CB . GLN C 3 1 ? -31.351 6.027 5.710 1.00 140.08 ? 1 GLN H CB 1 ATOM 3638 C CG . GLN C 3 1 ? -31.903 4.882 6.770 1.00 140.08 ? 1 GLN H CG 1 ATOM 3639 C CD . GLN C 3 1 ? -32.893 5.252 7.976 1.00 140.08 ? 1 GLN H CD 1 ATOM 3640 O OE1 . GLN C 3 1 ? -33.063 6.389 8.392 1.00 140.08 ? 1 GLN H OE1 1 ATOM 3641 N NE2 . GLN C 3 1 ? -33.562 4.222 8.484 1.00 140.08 ? 1 GLN H NE2 1 ATOM 3642 N N . VAL C 3 2 ? -30.851 3.023 4.852 1.00 87.27 ? 2 VAL H N 1 ATOM 3643 C CA . VAL C 3 2 ? -31.434 1.686 5.201 1.00 87.27 ? 2 VAL H CA 1 ATOM 3644 C C . VAL C 3 2 ? -30.605 1.161 6.339 1.00 87.27 ? 2 VAL H C 1 ATOM 3645 O O . VAL C 3 2 ? -29.423 1.257 6.243 1.00 87.27 ? 2 VAL H O 1 ATOM 3646 C CB . VAL C 3 2 ? -31.545 0.661 4.112 1.00 16.42 ? 2 VAL H CB 1 ATOM 3647 C CG1 . VAL C 3 2 ? -30.255 0.572 3.294 1.00 16.42 ? 2 VAL H CG1 1 ATOM 3648 C CG2 . VAL C 3 2 ? -31.630 -0.726 4.814 1.00 16.42 ? 2 VAL H CG2 1 ATOM 3649 N N . GLN C 3 3 ? -31.104 0.550 7.386 1.00 68.13 ? 3 GLN H N 1 ATOM 3650 C CA . GLN C 3 3 ? -30.128 0.154 8.421 1.00 68.13 ? 3 GLN H CA 1 ATOM 3651 C C . GLN C 3 3 ? -30.294 -1.197 9.039 1.00 68.13 ? 3 GLN H C 1 ATOM 3652 O O . GLN C 3 3 ? -31.358 -1.767 8.949 1.00 68.13 ? 3 GLN H O 1 ATOM 3653 C CB . GLN C 3 3 ? -30.122 1.155 9.584 1.00 65.88 ? 3 GLN H CB 1 ATOM 3654 C CG . GLN C 3 3 ? -29.550 2.469 9.245 1.00 65.88 ? 3 GLN H CG 1 ATOM 3655 C CD . GLN C 3 3 ? -29.563 3.416 10.364 1.00 65.88 ? 3 GLN H CD 1 ATOM 3656 O OE1 . GLN C 3 3 ? -28.664 3.431 11.114 1.00 65.88 ? 3 GLN H OE1 1 ATOM 3657 N NE2 . GLN C 3 3 ? -30.597 4.212 10.486 1.00 65.88 ? 3 GLN H NE2 1 ATOM 3658 N N . VAL C 3 4 ? -29.225 -1.787 9.526 1.00 81.44 ? 4 VAL H N 1 ATOM 3659 C CA . VAL C 3 4 ? -29.370 -2.966 10.334 1.00 81.44 ? 4 VAL H CA 1 ATOM 3660 C C . VAL C 3 4 ? -28.603 -2.858 11.617 1.00 81.44 ? 4 VAL H C 1 ATOM 3661 O O . VAL C 3 4 ? -27.393 -2.606 11.593 1.00 81.44 ? 4 VAL H O 1 ATOM 3662 C CB . VAL C 3 4 ? -29.027 -4.193 9.609 1.00 20.50 ? 4 VAL H CB 1 ATOM 3663 C CG1 . VAL C 3 4 ? -29.207 -5.376 10.529 1.00 20.50 ? 4 VAL H CG1 1 ATOM 3664 C CG2 . VAL C 3 4 ? -30.006 -4.415 8.639 1.00 20.50 ? 4 VAL H CG2 1 ATOM 3665 N N . VAL C 3 5 ? -29.252 -3.143 12.738 1.00 66.18 ? 5 VAL H N 1 ATOM 3666 C CA . VAL C 3 5 ? -28.539 -3.008 13.993 1.00 66.18 ? 5 VAL H CA 1 ATOM 3667 C C . VAL C 3 5 ? -28.581 -4.280 14.775 1.00 66.18 ? 5 VAL H C 1 ATOM 3668 O O . VAL C 3 5 ? -29.633 -4.899 14.927 1.00 66.18 ? 5 VAL H O 1 ATOM 3669 C CB . VAL C 3 5 ? -29.084 -1.928 14.876 1.00 46.95 ? 5 VAL H CB 1 ATOM 3670 C CG1 . VAL C 3 5 ? -28.260 -1.912 16.109 1.00 46.95 ? 5 VAL H CG1 1 ATOM 3671 C CG2 . VAL C 3 5 ? -29.146 -0.590 14.180 1.00 46.95 ? 5 VAL H CG2 1 ATOM 3672 N N . GLN C 3 6 ? -27.438 -4.717 15.220 1.00 85.51 ? 6 GLN H N 1 ATOM 3673 C CA . GLN C 3 6 ? -27.394 -5.900 16.004 1.00 85.51 ? 6 GLN H CA 1 ATOM 3674 C C . GLN C 3 6 ? -27.008 -5.491 17.382 1.00 85.51 ? 6 GLN H C 1 ATOM 3675 O O . GLN C 3 6 ? -26.271 -4.565 17.593 1.00 85.51 ? 6 GLN H O 1 ATOM 3676 C CB . GLN C 3 6 ? -26.437 -6.906 15.446 1.00 79.13 ? 6 GLN H CB 1 ATOM 3677 C CG . GLN C 3 6 ? -26.915 -7.497 14.177 1.00 79.13 ? 6 GLN H CG 1 ATOM 3678 C CD . GLN C 3 6 ? -25.986 -8.523 13.566 1.00 79.13 ? 6 GLN H CD 1 ATOM 3679 O OE1 . GLN C 3 6 ? -24.889 -8.207 13.159 1.00 79.13 ? 6 GLN H OE1 1 ATOM 3680 N NE2 . GLN C 3 6 ? -26.433 -9.764 13.512 1.00 79.13 ? 6 GLN H NE2 1 ATOM 3681 N N . SER C 3 7 ? -27.469 -6.258 18.326 1.00 65.81 ? 7 SER H N 1 ATOM 3682 C CA . SER C 3 7 ? -27.327 -6.034 19.736 1.00 65.81 ? 7 SER H CA 1 ATOM 3683 C C . SER C 3 7 ? -25.908 -6.234 20.139 1.00 65.81 ? 7 SER H C 1 ATOM 3684 O O . SER C 3 7 ? -25.100 -6.677 19.355 1.00 65.81 ? 7 SER H O 1 ATOM 3685 C CB . SER C 3 7 ? -28.126 -7.055 20.456 1.00 48.93 ? 7 SER H CB 1 ATOM 3686 O OG . SER C 3 7 ? -27.558 -8.312 20.187 1.00 48.93 ? 7 SER H OG 1 ATOM 3687 N N . GLY C 3 8 ? -25.569 -5.730 21.310 1.00 70.34 ? 8 GLY H N 1 ATOM 3688 C CA . GLY C 3 8 ? -24.212 -5.860 21.813 1.00 70.34 ? 8 GLY H CA 1 ATOM 3689 C C . GLY C 3 8 ? -23.595 -7.250 22.031 1.00 70.34 ? 8 GLY H C 1 ATOM 3690 O O . GLY C 3 8 ? -24.222 -8.281 22.354 1.00 70.34 ? 8 GLY H O 1 ATOM 3691 N N . ALA C 3 9 ? -22.284 -7.222 21.861 1.00 84.09 ? 9 ALA H N 1 ATOM 3692 C CA . ALA C 3 9 ? -21.493 -8.408 21.869 1.00 84.09 ? 9 ALA H CA 1 ATOM 3693 C C . ALA C 3 9 ? -21.635 -9.114 23.196 1.00 84.09 ? 9 ALA H C 1 ATOM 3694 O O . ALA C 3 9 ? -21.639 -8.484 24.201 1.00 84.09 ? 9 ALA H O 1 ATOM 3695 C CB . ALA C 3 9 ? -20.006 -7.986 21.494 1.00 12.02 ? 9 ALA H CB 1 ATOM 3696 N N . GLU C 3 10 ? -21.718 -10.437 23.178 1.00 62.00 ? 10 GLU H N 1 ATOM 3697 C CA . GLU C 3 10 ? -21.927 -11.203 24.387 1.00 62.00 ? 10 GLU H CA 1 ATOM 3698 C C . GLU C 3 10 ? -21.116 -12.497 24.684 1.00 62.00 ? 10 GLU H C 1 ATOM 3699 O O . GLU C 3 10 ? -20.661 -13.158 23.749 1.00 62.00 ? 10 GLU H O 1 ATOM 3700 C CB . GLU C 3 10 ? -23.412 -11.435 24.547 1.00 79.18 ? 10 GLU H CB 1 ATOM 3701 C CG . GLU C 3 10 ? -23.718 -12.055 25.864 1.00 79.18 ? 10 GLU H CG 1 ATOM 3702 C CD . GLU C 3 10 ? -25.197 -12.155 26.084 1.00 79.18 ? 10 GLU H CD 1 ATOM 3703 O OE1 . GLU C 3 10 ? -25.984 -11.729 25.194 1.00 79.18 ? 10 GLU H OE1 1 ATOM 3704 O OE2 . GLU C 3 10 ? -25.562 -12.633 27.181 1.00 79.18 ? 10 GLU H OE2 1 ATOM 3705 N N . VAL C 3 11 ? -20.905 -12.827 25.972 1.00 70.29 ? 11 VAL H N 1 ATOM 3706 C CA . VAL C 3 11 ? -20.117 -14.018 26.420 1.00 70.29 ? 11 VAL H CA 1 ATOM 3707 C C . VAL C 3 11 ? -20.923 -15.133 27.121 1.00 70.29 ? 11 VAL H C 1 ATOM 3708 O O . VAL C 3 11 ? -21.703 -14.849 28.001 1.00 70.29 ? 11 VAL H O 1 ATOM 3709 C CB . VAL C 3 11 ? -19.118 -13.643 27.446 1.00 72.05 ? 11 VAL H CB 1 ATOM 3710 C CG1 . VAL C 3 11 ? -18.360 -14.865 27.859 1.00 72.05 ? 11 VAL H CG1 1 ATOM 3711 C CG2 . VAL C 3 11 ? -18.238 -12.554 26.929 1.00 72.05 ? 11 VAL H CG2 1 ATOM 3712 N N . ARG C 3 12 ? -20.768 -16.395 26.700 1.00 69.64 ? 12 ARG H N 1 ATOM 3713 C CA . ARG C 3 12 ? -21.538 -17.552 27.255 1.00 69.64 ? 12 ARG H CA 1 ATOM 3714 C C . ARG C 3 12 ? -20.890 -18.845 27.765 1.00 69.64 ? 12 ARG H C 1 ATOM 3715 O O . ARG C 3 12 ? -20.002 -19.380 27.160 1.00 69.64 ? 12 ARG H O 1 ATOM 3716 C CB . ARG C 3 12 ? -22.582 -18.043 26.226 1.00 89.64 ? 12 ARG H CB 1 ATOM 3717 C CG . ARG C 3 12 ? -23.590 -17.051 25.816 1.00 89.64 ? 12 ARG H CG 1 ATOM 3718 C CD . ARG C 3 12 ? -24.456 -16.829 26.945 1.00 89.64 ? 12 ARG H CD 1 ATOM 3719 N NE . ARG C 3 12 ? -25.589 -16.057 26.552 1.00 89.64 ? 12 ARG H NE 1 ATOM 3720 C CZ . ARG C 3 12 ? -26.184 -15.192 27.349 1.00 89.64 ? 12 ARG H CZ 1 ATOM 3721 N NH1 . ARG C 3 12 ? -25.697 -15.019 28.566 1.00 89.64 ? 12 ARG H NH1 1 ATOM 3722 N NH2 . ARG C 3 12 ? -27.276 -14.522 26.937 1.00 89.64 ? 12 ARG H NH2 1 ATOM 3723 N N . LYS C 3 13 ? -21.426 -19.412 28.825 1.00 77.01 ? 13 LYS H N 1 ATOM 3724 C CA . LYS C 3 13 ? -20.929 -20.692 29.349 1.00 77.01 ? 13 LYS H CA 1 ATOM 3725 C C . LYS C 3 13 ? -21.459 -21.885 28.514 1.00 77.01 ? 13 LYS H C 1 ATOM 3726 O O . LYS C 3 13 ? -22.623 -21.947 28.242 1.00 77.01 ? 13 LYS H O 1 ATOM 3727 C CB . LYS C 3 13 ? -21.402 -20.837 30.790 1.00 93.88 ? 13 LYS H CB 1 ATOM 3728 C CG . LYS C 3 13 ? -20.905 -19.763 31.724 1.00 93.88 ? 13 LYS H CG 1 ATOM 3729 C CD . LYS C 3 13 ? -19.409 -19.862 31.899 1.00 93.88 ? 13 LYS H CD 1 ATOM 3730 C CE . LYS C 3 13 ? -18.912 -18.940 33.006 1.00 93.88 ? 13 LYS H CE 1 ATOM 3731 N NZ . LYS C 3 13 ? -18.893 -17.498 32.618 1.00 93.88 ? 13 LYS H NZ 1 ATOM 3732 N N . PRO C 3 14 ? -20.637 -22.873 28.147 1.00 77.94 ? 14 PRO H N 1 ATOM 3733 C CA . PRO C 3 14 ? -21.180 -23.994 27.357 1.00 77.94 ? 14 PRO H CA 1 ATOM 3734 C C . PRO C 3 14 ? -22.419 -24.461 27.979 1.00 77.94 ? 14 PRO H C 1 ATOM 3735 O O . PRO C 3 14 ? -22.417 -24.549 29.155 1.00 77.94 ? 14 PRO H O 1 ATOM 3736 C CB . PRO C 3 14 ? -20.137 -25.083 27.467 1.00 57.19 ? 14 PRO H CB 1 ATOM 3737 C CG . PRO C 3 14 ? -19.083 -24.475 28.404 1.00 57.19 ? 14 PRO H CG 1 ATOM 3738 C CD . PRO C 3 14 ? -19.188 -22.996 28.280 1.00 57.19 ? 14 PRO H CD 1 ATOM 3739 N N . GLY C 3 15 ? -23.412 -24.863 27.177 1.00 80.39 ? 15 GLY H N 1 ATOM 3740 C CA . GLY C 3 15 ? -24.729 -25.310 27.625 1.00 80.39 ? 15 GLY H CA 1 ATOM 3741 C C . GLY C 3 15 ? -25.861 -24.296 27.787 1.00 80.39 ? 15 GLY H C 1 ATOM 3742 O O . GLY C 3 15 ? -27.033 -24.701 27.938 1.00 80.39 ? 15 GLY H O 1 ATOM 3743 N N . ALA C 3 16 ? -25.545 -23.002 27.707 1.00 84.20 ? 16 ALA H N 1 ATOM 3744 C CA . ALA C 3 16 ? -26.526 -21.904 27.838 1.00 84.20 ? 16 ALA H CA 1 ATOM 3745 C C . ALA C 3 16 ? -27.016 -21.263 26.489 1.00 84.20 ? 16 ALA H C 1 ATOM 3746 O O . ALA C 3 16 ? -26.254 -21.054 25.530 1.00 84.20 ? 16 ALA H O 1 ATOM 3747 C CB . ALA C 3 16 ? -25.992 -20.825 28.797 1.00 100.58 ? 16 ALA H CB 1 ATOM 3748 N N . SER C 3 17 ? -28.301 -20.961 26.424 1.00 78.09 ? 17 SER H N 1 ATOM 3749 C CA . SER C 3 17 ? -28.835 -20.410 25.212 1.00 78.09 ? 17 SER H CA 1 ATOM 3750 C C . SER C 3 17 ? -28.266 -18.996 25.094 1.00 78.09 ? 17 SER H C 1 ATOM 3751 O O . SER C 3 17 ? -27.704 -18.457 26.043 1.00 78.09 ? 17 SER H O 1 ATOM 3752 C CB . SER C 3 17 ? -30.381 -20.274 25.269 1.00 65.16 ? 17 SER H CB 1 ATOM 3753 O OG . SER C 3 17 ? -30.861 -19.257 26.163 1.00 65.16 ? 17 SER H OG 1 ATOM 3754 N N . VAL C 3 18 ? -28.295 -18.471 23.863 1.00 77.20 ? 18 VAL H N 1 ATOM 3755 C CA . VAL C 3 18 ? -27.898 -17.097 23.543 1.00 77.20 ? 18 VAL H CA 1 ATOM 3756 C C . VAL C 3 18 ? -29.029 -16.570 22.663 1.00 77.20 ? 18 VAL H C 1 ATOM 3757 O O . VAL C 3 18 ? -29.592 -17.330 21.895 1.00 77.20 ? 18 VAL H O 1 ATOM 3758 C CB . VAL C 3 18 ? -26.494 -17.062 22.847 1.00 75.55 ? 18 VAL H CB 1 ATOM 3759 C CG1 . VAL C 3 18 ? -26.469 -17.929 21.621 1.00 75.55 ? 18 VAL H CG1 1 ATOM 3760 C CG2 . VAL C 3 18 ? -26.141 -15.665 22.480 1.00 75.55 ? 18 VAL H CG2 1 ATOM 3761 N N . LYS C 3 19 ? -29.459 -15.328 22.849 1.00 90.68 ? 19 LYS H N 1 ATOM 3762 C CA . LYS C 3 19 ? -30.501 -14.850 21.959 1.00 90.68 ? 19 LYS H CA 1 ATOM 3763 C C . LYS C 3 19 ? -30.007 -13.490 21.435 1.00 90.68 ? 19 LYS H C 1 ATOM 3764 O O . LYS C 3 19 ? -29.697 -12.610 22.240 1.00 90.68 ? 19 LYS H O 1 ATOM 3765 C CB . LYS C 3 19 ? -31.824 -14.810 22.779 1.00 55.72 ? 19 LYS H CB 1 ATOM 3766 C CG . LYS C 3 19 ? -33.144 -14.364 22.078 1.00 55.72 ? 19 LYS H CG 1 ATOM 3767 C CD . LYS C 3 19 ? -34.326 -14.389 23.034 1.00 55.72 ? 19 LYS H CD 1 ATOM 3768 C CE . LYS C 3 19 ? -35.702 -13.975 22.467 1.00 55.72 ? 19 LYS H CE 1 ATOM 3769 N NZ . LYS C 3 19 ? -36.546 -14.952 21.638 1.00 55.72 ? 19 LYS H NZ 1 ATOM 3770 N N . VAL C 3 20 ? -30.040 -13.297 20.104 1.00 74.63 ? 20 VAL H N 1 ATOM 3771 C CA . VAL C 3 20 ? -29.543 -12.055 19.478 1.00 74.63 ? 20 VAL H CA 1 ATOM 3772 C C . VAL C 3 20 ? -30.529 -11.191 18.643 1.00 74.63 ? 20 VAL H C 1 ATOM 3773 O O . VAL C 3 20 ? -31.032 -11.664 17.644 1.00 74.63 ? 20 VAL H O 1 ATOM 3774 C CB . VAL C 3 20 ? -28.382 -12.403 18.534 1.00 51.15 ? 20 VAL H CB 1 ATOM 3775 C CG1 . VAL C 3 20 ? -27.848 -11.135 17.873 1.00 51.15 ? 20 VAL H CG1 1 ATOM 3776 C CG2 . VAL C 3 20 ? -27.339 -13.135 19.261 1.00 51.15 ? 20 VAL H CG2 1 ATOM 3777 N N . SER C 3 21 ? -30.733 -9.915 18.998 1.00 122.87 ? 21 SER H N 1 ATOM 3778 C CA . SER C 3 21 ? -31.645 -9.046 18.248 1.00 122.87 ? 21 SER H CA 1 ATOM 3779 C C . SER C 3 21 ? -31.137 -8.396 16.954 1.00 122.87 ? 21 SER H C 1 ATOM 3780 O O . SER C 3 21 ? -29.937 -8.242 16.752 1.00 122.87 ? 21 SER H O 1 ATOM 3781 C CB . SER C 3 21 ? -32.229 -7.961 19.177 1.00 100.32 ? 21 SER H CB 1 ATOM 3782 O OG . SER C 3 21 ? -31.257 -7.086 19.700 1.00 100.32 ? 21 SER H OG 1 ATOM 3783 N N . CYS C 3 22 ? -32.082 -7.978 16.112 1.00 47.51 ? 22 CYS H N 1 ATOM 3784 C CA . CYS C 3 22 ? -31.856 -7.252 14.841 1.00 47.51 ? 22 CYS H CA 1 ATOM 3785 C C . CYS C 3 22 ? -32.905 -6.123 14.684 1.00 47.51 ? 22 CYS H C 1 ATOM 3786 O O . CYS C 3 22 ? -34.092 -6.341 14.866 1.00 47.51 ? 22 CYS H O 1 ATOM 3787 C CB . CYS C 3 22 ? -31.976 -8.227 13.661 1.00 68.94 ? 22 CYS H CB 1 ATOM 3788 S SG . CYS C 3 22 ? -30.848 -7.574 12.430 1.00 68.94 ? 22 CYS H SG 1 ATOM 3789 N N . LYS C 3 23 ? -32.536 -4.898 14.388 1.00 72.65 ? 23 LYS H N 1 ATOM 3790 C CA . LYS C 3 23 ? -33.641 -3.966 14.162 1.00 72.65 ? 23 LYS H CA 1 ATOM 3791 C C . LYS C 3 23 ? -33.450 -3.418 12.731 1.00 72.65 ? 23 LYS H C 1 ATOM 3792 O O . LYS C 3 23 ? -32.307 -3.246 12.299 1.00 72.65 ? 23 LYS H O 1 ATOM 3793 C CB . LYS C 3 23 ? -33.818 -2.881 15.228 1.00 73.92 ? 23 LYS H CB 1 ATOM 3794 C CG . LYS C 3 23 ? -35.160 -2.166 14.941 1.00 73.92 ? 23 LYS H CG 1 ATOM 3795 C CD . LYS C 3 23 ? -35.588 -1.018 15.874 1.00 73.92 ? 23 LYS H CD 1 ATOM 3796 C CE . LYS C 3 23 ? -36.961 -0.466 15.384 1.00 73.92 ? 23 LYS H CE 1 ATOM 3797 N NZ . LYS C 3 23 ? -37.626 0.412 16.339 1.00 73.92 ? 23 LYS H NZ 1 ATOM 3798 N N . VAL C 3 24 ? -34.509 -3.243 11.943 1.00 86.63 ? 24 VAL H N 1 ATOM 3799 C CA . VAL C 3 24 ? -34.301 -2.846 10.566 1.00 86.63 ? 24 VAL H CA 1 ATOM 3800 C C . VAL C 3 24 ? -35.001 -1.513 10.348 1.00 86.63 ? 24 VAL H C 1 ATOM 3801 O O . VAL C 3 24 ? -36.140 -1.337 10.731 1.00 86.63 ? 24 VAL H O 1 ATOM 3802 C CB . VAL C 3 24 ? -34.872 -3.871 9.618 1.00 58.55 ? 24 VAL H CB 1 ATOM 3803 C CG1 . VAL C 3 24 ? -34.628 -3.409 8.243 1.00 58.55 ? 24 VAL H CG1 1 ATOM 3804 C CG2 . VAL C 3 24 ? -34.411 -5.252 9.893 1.00 58.55 ? 24 VAL H CG2 1 ATOM 3805 N N . SER C 3 25 ? -34.321 -0.545 9.787 1.00 37.99 ? 25 SER H N 1 ATOM 3806 C CA . SER C 3 25 ? -34.949 0.754 9.563 1.00 37.99 ? 25 SER H CA 1 ATOM 3807 C C . SER C 3 25 ? -34.949 1.034 8.052 1.00 37.99 ? 25 SER H C 1 ATOM 3808 O O . SER C 3 25 ? -33.919 0.926 7.407 1.00 37.99 ? 25 SER H O 1 ATOM 3809 C CB . SER C 3 25 ? -34.177 1.885 10.272 1.00 59.94 ? 25 SER H CB 1 ATOM 3810 O OG . SER C 3 25 ? -34.332 1.776 11.667 1.00 59.94 ? 25 SER H OG 1 ATOM 3811 N N . GLY C 3 26 ? -36.048 1.603 7.542 1.00 68.56 ? 26 GLY H N 1 ATOM 3812 C CA . GLY C 3 26 ? -36.240 1.834 6.116 1.00 68.56 ? 26 GLY H CA 1 ATOM 3813 C C . GLY C 3 26 ? -37.208 0.913 5.406 1.00 68.56 ? 26 GLY H C 1 ATOM 3814 O O . GLY C 3 26 ? -37.431 1.068 4.259 1.00 68.56 ? 26 GLY H O 1 ATOM 3815 N N . PHE C 3 27 ? -37.672 -0.123 6.048 1.00 78.88 ? 27 PHE H N 1 ATOM 3816 C CA . PHE C 3 27 ? -38.736 -0.992 5.567 1.00 78.88 ? 27 PHE H CA 1 ATOM 3817 C C . PHE C 3 27 ? -39.516 -1.871 6.503 1.00 78.88 ? 27 PHE H C 1 ATOM 3818 O O . PHE C 3 27 ? -39.154 -2.024 7.652 1.00 78.88 ? 27 PHE H O 1 ATOM 3819 C CB . PHE C 3 27 ? -38.481 -1.725 4.279 1.00 75.99 ? 27 PHE H CB 1 ATOM 3820 C CG . PHE C 3 27 ? -37.244 -2.478 4.199 1.00 75.99 ? 27 PHE H CG 1 ATOM 3821 C CD1 . PHE C 3 27 ? -36.117 -1.867 3.726 1.00 75.99 ? 27 PHE H CD1 1 ATOM 3822 C CD2 . PHE C 3 27 ? -37.212 -3.830 4.500 1.00 75.99 ? 27 PHE H CD2 1 ATOM 3823 C CE1 . PHE C 3 27 ? -34.984 -2.590 3.524 1.00 75.99 ? 27 PHE H CE1 1 ATOM 3824 C CE2 . PHE C 3 27 ? -36.061 -4.567 4.312 1.00 75.99 ? 27 PHE H CE2 1 ATOM 3825 C CZ . PHE C 3 27 ? -34.958 -3.941 3.819 1.00 75.99 ? 27 PHE H CZ 1 ATOM 3826 N N . THR C 3 28 ? -40.643 -2.404 6.091 1.00 69.53 ? 28 THR H N 1 ATOM 3827 C CA . THR C 3 28 ? -41.308 -3.279 7.046 1.00 69.53 ? 28 THR H CA 1 ATOM 3828 C C . THR C 3 28 ? -40.966 -4.684 6.636 1.00 69.53 ? 28 THR H C 1 ATOM 3829 O O . THR C 3 28 ? -41.249 -5.100 5.508 1.00 69.53 ? 28 THR H O 1 ATOM 3830 C CB . THR C 3 28 ? -42.823 -3.067 7.114 1.00 159.83 ? 28 THR H CB 1 ATOM 3831 O OG1 . THR C 3 28 ? -43.083 -1.730 7.535 1.00 159.83 ? 28 THR H OG1 1 ATOM 3832 C CG2 . THR C 3 28 ? -43.465 -4.020 8.110 1.00 159.83 ? 28 THR H CG2 1 ATOM 3833 N N . LEU C 3 29 ? -40.381 -5.402 7.611 1.00 41.70 ? 29 LEU H N 1 ATOM 3834 C CA . LEU C 3 29 ? -39.826 -6.730 7.436 1.00 41.70 ? 29 LEU H CA 1 ATOM 3835 C C . LEU C 3 29 ? -41.049 -7.614 7.075 1.00 41.70 ? 29 LEU H C 1 ATOM 3836 O O . LEU C 3 29 ? -42.044 -7.630 7.741 1.00 41.70 ? 29 LEU H O 1 ATOM 3837 C CB . LEU C 3 29 ? -39.140 -6.942 8.798 1.00 30.89 ? 29 LEU H CB 1 ATOM 3838 C CG . LEU C 3 29 ? -38.336 -8.077 9.414 1.00 30.89 ? 29 LEU H CG 1 ATOM 3839 C CD1 . LEU C 3 29 ? -37.083 -7.975 8.572 1.00 30.89 ? 29 LEU H CD1 1 ATOM 3840 C CD2 . LEU C 3 29 ? -37.943 -7.935 10.905 1.00 30.89 ? 29 LEU H CD2 1 ATOM 3841 N N . THR C 3 30 ? -40.938 -8.354 5.978 1.00 83.41 ? 30 THR H N 1 ATOM 3842 C CA . THR C 3 30 ? -42.063 -9.134 5.409 1.00 83.41 ? 30 THR H CA 1 ATOM 3843 C C . THR C 3 30 ? -42.470 -10.323 6.213 1.00 83.41 ? 30 THR H C 1 ATOM 3844 O O . THR C 3 30 ? -43.554 -10.849 6.098 1.00 83.41 ? 30 THR H O 1 ATOM 3845 C CB . THR C 3 30 ? -41.801 -9.633 3.971 1.00 77.93 ? 30 THR H CB 1 ATOM 3846 O OG1 . THR C 3 30 ? -40.804 -10.651 3.982 1.00 77.93 ? 30 THR H OG1 1 ATOM 3847 C CG2 . THR C 3 30 ? -41.230 -8.437 3.107 1.00 77.93 ? 30 THR H CG2 1 ATOM 3848 N N . GLY C 3 31 ? -41.537 -10.729 7.043 1.00 83.64 ? 31 GLY H N 1 ATOM 3849 C CA . GLY C 3 31 ? -41.632 -11.924 7.859 1.00 83.64 ? 31 GLY H CA 1 ATOM 3850 C C . GLY C 3 31 ? -40.928 -13.088 7.140 1.00 83.64 ? 31 GLY H C 1 ATOM 3851 O O . GLY C 3 31 ? -40.636 -14.077 7.829 1.00 83.64 ? 31 GLY H O 1 ATOM 3852 N N . LEU C 3 32 ? -40.657 -12.983 5.808 1.00 90.29 ? 32 LEU H N 1 ATOM 3853 C CA . LEU C 3 32 ? -39.852 -13.971 4.997 1.00 90.29 ? 32 LEU H CA 1 ATOM 3854 C C . LEU C 3 32 ? -38.433 -13.423 4.787 1.00 90.29 ? 32 LEU H C 1 ATOM 3855 O O . LEU C 3 32 ? -37.502 -14.068 4.274 1.00 90.29 ? 32 LEU H O 1 ATOM 3856 C CB . LEU C 3 32 ? -40.466 -14.085 3.614 1.00 86.64 ? 32 LEU H CB 1 ATOM 3857 C CG . LEU C 3 32 ? -41.894 -14.557 3.595 1.00 86.64 ? 32 LEU H CG 1 ATOM 3858 C CD1 . LEU C 3 32 ? -42.357 -14.510 2.205 1.00 86.64 ? 32 LEU H CD1 1 ATOM 3859 C CD2 . LEU C 3 32 ? -41.987 -15.975 4.111 1.00 86.64 ? 32 LEU H CD2 1 ATOM 3860 N N . SER C 3 33 ? -38.305 -12.223 5.301 1.00 43.65 ? 33 SER H N 1 ATOM 3861 C CA . SER C 3 33 ? -37.176 -11.373 5.136 1.00 43.65 ? 33 SER H CA 1 ATOM 3862 C C . SER C 3 33 ? -35.769 -11.745 5.580 1.00 43.65 ? 33 SER H C 1 ATOM 3863 O O . SER C 3 33 ? -34.797 -11.467 4.823 1.00 43.65 ? 33 SER H O 1 ATOM 3864 C CB . SER C 3 33 ? -37.569 -10.015 5.715 1.00 96.15 ? 33 SER H CB 1 ATOM 3865 O OG . SER C 3 33 ? -38.642 -9.465 4.980 1.00 96.15 ? 33 SER H OG 1 ATOM 3866 N N . ILE C 3 34 ? -35.681 -12.388 6.758 1.00 73.23 ? 34 ILE H N 1 ATOM 3867 C CA . ILE C 3 34 ? -34.434 -12.626 7.441 1.00 73.23 ? 34 ILE H CA 1 ATOM 3868 C C . ILE C 3 34 ? -33.744 -13.954 7.636 1.00 73.23 ? 34 ILE H C 1 ATOM 3869 O O . ILE C 3 34 ? -34.360 -14.921 8.093 1.00 73.23 ? 34 ILE H O 1 ATOM 3870 C CB . ILE C 3 34 ? -34.539 -12.051 8.831 1.00 60.13 ? 34 ILE H CB 1 ATOM 3871 C CG1 . ILE C 3 34 ? -34.805 -10.581 8.738 1.00 60.13 ? 34 ILE H CG1 1 ATOM 3872 C CG2 . ILE C 3 34 ? -33.314 -12.302 9.620 1.00 60.13 ? 34 ILE H CG2 1 ATOM 3873 C CD1 . ILE C 3 34 ? -35.137 -10.065 10.033 1.00 60.13 ? 34 ILE H CD1 1 ATOM 3874 N N . HIS C 3 35 ? -32.436 -13.938 7.284 1.00 91.19 ? 35 HIS H N 1 ATOM 3875 C CA . HIS C 3 35 ? -31.471 -15.057 7.384 1.00 91.19 ? 35 HIS H CA 1 ATOM 3876 C C . HIS C 3 35 ? -30.338 -14.687 8.282 1.00 91.19 ? 35 HIS H C 1 ATOM 3877 O O . HIS C 3 35 ? -29.799 -13.593 8.192 1.00 91.19 ? 35 HIS H O 1 ATOM 3878 C CB . HIS C 3 35 ? -30.772 -15.460 6.079 1.00 96.35 ? 35 HIS H CB 1 ATOM 3879 C CG . HIS C 3 35 ? -31.659 -16.118 5.085 1.00 96.35 ? 35 HIS H CG 1 ATOM 3880 N ND1 . HIS C 3 35 ? -32.358 -15.413 4.132 1.00 96.35 ? 35 HIS H ND1 1 ATOM 3881 C CD2 . HIS C 3 35 ? -31.971 -17.421 4.896 1.00 96.35 ? 35 HIS H CD2 1 ATOM 3882 C CE1 . HIS C 3 35 ? -33.066 -16.253 3.395 1.00 96.35 ? 35 HIS H CE1 1 ATOM 3883 N NE2 . HIS C 3 35 ? -32.849 -17.478 3.840 1.00 96.35 ? 35 HIS H NE2 1 ATOM 3884 N N . TRP C 3 36 ? -30.068 -15.598 9.215 1.00 66.72 ? 36 TRP H N 1 ATOM 3885 C CA . TRP C 3 36 ? -28.990 -15.531 10.197 1.00 66.72 ? 36 TRP H CA 1 ATOM 3886 C C . TRP C 3 36 ? -27.776 -16.389 9.778 1.00 66.72 ? 36 TRP H C 1 ATOM 3887 O O . TRP C 3 36 ? -27.822 -17.593 9.732 1.00 66.72 ? 36 TRP H O 1 ATOM 3888 C CB . TRP C 3 36 ? -29.586 -16.050 11.512 1.00 83.11 ? 36 TRP H CB 1 ATOM 3889 C CG . TRP C 3 36 ? -29.559 -15.104 12.622 1.00 83.11 ? 36 TRP H CG 1 ATOM 3890 C CD1 . TRP C 3 36 ? -28.780 -15.205 13.724 1.00 83.11 ? 36 TRP H CD1 1 ATOM 3891 C CD2 . TRP C 3 36 ? -30.220 -13.872 12.734 1.00 83.11 ? 36 TRP H CD2 1 ATOM 3892 N NE1 . TRP C 3 36 ? -28.902 -14.111 14.524 1.00 83.11 ? 36 TRP H NE1 1 ATOM 3893 C CE2 . TRP C 3 36 ? -29.778 -13.263 13.940 1.00 83.11 ? 36 TRP H CE2 1 ATOM 3894 C CE3 . TRP C 3 36 ? -31.124 -13.217 11.955 1.00 83.11 ? 36 TRP H CE3 1 ATOM 3895 C CZ2 . TRP C 3 36 ? -30.204 -12.047 14.375 1.00 83.11 ? 36 TRP H CZ2 1 ATOM 3896 C CZ3 . TRP C 3 36 ? -31.562 -11.984 12.391 1.00 83.11 ? 36 TRP H CZ3 1 ATOM 3897 C CH2 . TRP C 3 36 ? -31.091 -11.411 13.606 1.00 83.11 ? 36 TRP H CH2 1 ATOM 3898 N N . VAL C 3 37 ? -26.670 -15.722 9.588 1.00 52.62 ? 37 VAL H N 1 ATOM 3899 C CA . VAL C 3 37 ? -25.301 -16.180 9.235 1.00 52.62 ? 37 VAL H CA 1 ATOM 3900 C C . VAL C 3 37 ? -24.135 -15.832 10.151 1.00 52.62 ? 37 VAL H C 1 ATOM 3901 O O . VAL C 3 37 ? -23.970 -14.661 10.507 1.00 52.62 ? 37 VAL H O 1 ATOM 3902 C CB . VAL C 3 37 ? -24.934 -15.908 7.786 1.00 37.21 ? 37 VAL H CB 1 ATOM 3903 C CG1 . VAL C 3 37 ? -23.554 -16.380 7.556 1.00 37.21 ? 37 VAL H CG1 1 ATOM 3904 C CG2 . VAL C 3 37 ? -25.773 -16.787 6.923 1.00 37.21 ? 37 VAL H CG2 1 ATOM 3905 N N . ARG C 3 38 ? -23.310 -16.799 10.536 1.00 86.20 ? 38 ARG H N 1 ATOM 3906 C CA . ARG C 3 38 ? -22.279 -16.418 11.502 1.00 86.20 ? 38 ARG H CA 1 ATOM 3907 C C . ARG C 3 38 ? -20.925 -16.893 11.005 1.00 86.20 ? 38 ARG H C 1 ATOM 3908 O O . ARG C 3 38 ? -20.816 -17.919 10.375 1.00 86.20 ? 38 ARG H O 1 ATOM 3909 C CB . ARG C 3 38 ? -22.507 -17.197 12.793 1.00 79.84 ? 38 ARG H CB 1 ATOM 3910 C CG . ARG C 3 38 ? -22.167 -18.661 12.518 1.00 79.84 ? 38 ARG H CG 1 ATOM 3911 C CD . ARG C 3 38 ? -22.435 -19.603 13.624 1.00 79.84 ? 38 ARG H CD 1 ATOM 3912 N NE . ARG C 3 38 ? -21.853 -20.891 13.291 1.00 79.84 ? 38 ARG H NE 1 ATOM 3913 C CZ . ARG C 3 38 ? -21.686 -21.867 14.172 1.00 79.84 ? 38 ARG H CZ 1 ATOM 3914 N NH1 . ARG C 3 38 ? -22.089 -21.708 15.443 1.00 79.84 ? 38 ARG H NH1 1 ATOM 3915 N NH2 . ARG C 3 38 ? -21.001 -22.951 13.806 1.00 79.84 ? 38 ARG H NH2 1 ATOM 3916 N N . GLN C 3 39 ? -19.897 -16.141 11.380 1.00 87.80 ? 39 GLN H N 1 ATOM 3917 C CA . GLN C 3 39 ? -18.507 -16.390 10.991 1.00 87.80 ? 39 GLN H CA 1 ATOM 3918 C C . GLN C 3 39 ? -17.605 -16.672 12.178 1.00 87.80 ? 39 GLN H C 1 ATOM 3919 O O . GLN C 3 39 ? -17.535 -15.911 13.135 1.00 87.80 ? 39 GLN H O 1 ATOM 3920 C CB . GLN C 3 39 ? -18.022 -15.180 10.163 1.00 52.85 ? 39 GLN H CB 1 ATOM 3921 C CG . GLN C 3 39 ? -16.653 -15.234 9.673 1.00 52.85 ? 39 GLN H CG 1 ATOM 3922 C CD . GLN C 3 39 ? -16.290 -14.033 8.839 1.00 52.85 ? 39 GLN H CD 1 ATOM 3923 O OE1 . GLN C 3 39 ? -17.143 -13.276 8.488 1.00 52.85 ? 39 GLN H OE1 1 ATOM 3924 N NE2 . GLN C 3 39 ? -15.001 -13.829 8.566 1.00 52.85 ? 39 GLN H NE2 1 ATOM 3925 N N . ALA C 3 40 ? -16.916 -17.797 12.086 1.00 151.91 ? 40 ALA H N 1 ATOM 3926 C CA . ALA C 3 40 ? -15.995 -18.227 13.120 1.00 151.91 ? 40 ALA H CA 1 ATOM 3927 C C . ALA C 3 40 ? -14.791 -17.308 13.116 1.00 151.91 ? 40 ALA H C 1 ATOM 3928 O O . ALA C 3 40 ? -14.497 -16.682 12.100 1.00 151.91 ? 40 ALA H O 1 ATOM 3929 C CB . ALA C 3 40 ? -15.563 -19.667 12.870 1.00 122.97 ? 40 ALA H CB 1 ATOM 3930 N N . PRO C 3 41 ? -14.058 -17.210 14.238 1.00 78.81 ? 41 PRO H N 1 ATOM 3931 C CA . PRO C 3 41 ? -12.969 -16.281 13.983 1.00 78.81 ? 41 PRO H CA 1 ATOM 3932 C C . PRO C 3 41 ? -11.954 -17.052 13.163 1.00 78.81 ? 41 PRO H C 1 ATOM 3933 O O . PRO C 3 41 ? -11.701 -18.225 13.488 1.00 78.81 ? 41 PRO H O 1 ATOM 3934 C CB . PRO C 3 41 ? -12.521 -15.914 15.382 1.00 92.23 ? 41 PRO H CB 1 ATOM 3935 C CG . PRO C 3 41 ? -13.773 -15.866 16.120 1.00 92.23 ? 41 PRO H CG 1 ATOM 3936 C CD . PRO C 3 41 ? -14.420 -17.183 15.662 1.00 92.23 ? 41 PRO H CD 1 ATOM 3937 N N . GLY C 3 42 ? -11.458 -16.429 12.072 1.00 92.55 ? 42 GLY H N 1 ATOM 3938 C CA . GLY C 3 42 ? -10.469 -17.068 11.209 1.00 92.55 ? 42 GLY H CA 1 ATOM 3939 C C . GLY C 3 42 ? -11.025 -17.895 10.048 1.00 92.55 ? 42 GLY H C 1 ATOM 3940 O O . GLY C 3 42 ? -10.256 -18.361 9.203 1.00 92.55 ? 42 GLY H O 1 ATOM 3941 N N . LYS C 3 43 ? -12.359 -17.995 9.976 1.00 112.64 ? 43 LYS H N 1 ATOM 3942 C CA . LYS C 3 43 ? -13.109 -18.851 9.054 1.00 112.64 ? 43 LYS H CA 1 ATOM 3943 C C . LYS C 3 43 ? -14.194 -18.246 8.182 1.00 112.64 ? 43 LYS H C 1 ATOM 3944 O O . LYS C 3 43 ? -14.604 -17.113 8.371 1.00 112.64 ? 43 LYS H O 1 ATOM 3945 C CB . LYS C 3 43 ? -13.630 -20.031 9.828 1.00 88.68 ? 43 LYS H CB 1 ATOM 3946 C CG . LYS C 3 43 ? -12.439 -20.794 10.190 1.00 88.68 ? 43 LYS H CG 1 ATOM 3947 C CD . LYS C 3 43 ? -12.639 -22.026 10.967 1.00 88.68 ? 43 LYS H CD 1 ATOM 3948 C CE . LYS C 3 43 ? -11.226 -22.603 11.202 1.00 88.68 ? 43 LYS H CE 1 ATOM 3949 N NZ . LYS C 3 43 ? -11.192 -23.858 12.002 1.00 88.68 ? 43 LYS H NZ 1 ATOM 3950 N N . GLY C 3 44 ? -14.534 -18.948 7.116 1.00 88.18 ? 44 GLY H N 1 ATOM 3951 C CA . GLY C 3 44 ? -15.527 -18.449 6.163 1.00 88.18 ? 44 GLY H CA 1 ATOM 3952 C C . GLY C 3 44 ? -16.979 -18.472 6.615 1.00 88.18 ? 44 GLY H C 1 ATOM 3953 O O . GLY C 3 44 ? -17.259 -18.823 7.777 1.00 88.18 ? 44 GLY H O 1 ATOM 3954 N N . LEU C 3 45 ? -17.881 -18.022 5.730 1.00 45.50 ? 45 LEU H N 1 ATOM 3955 C CA . LEU C 3 45 ? -19.307 -17.892 6.094 1.00 45.50 ? 45 LEU H CA 1 ATOM 3956 C C . LEU C 3 45 ? -20.027 -19.229 6.284 1.00 45.50 ? 45 LEU H C 1 ATOM 3957 O O . LEU C 3 45 ? -19.750 -20.158 5.531 1.00 45.50 ? 45 LEU H O 1 ATOM 3958 C CB . LEU C 3 45 ? -20.005 -17.012 5.040 1.00 48.89 ? 45 LEU H CB 1 ATOM 3959 C CG . LEU C 3 45 ? -19.493 -15.549 4.838 1.00 48.89 ? 45 LEU H CG 1 ATOM 3960 C CD1 . LEU C 3 45 ? -20.206 -14.883 3.775 1.00 48.89 ? 45 LEU H CD1 1 ATOM 3961 C CD2 . LEU C 3 45 ? -19.691 -14.724 6.017 1.00 48.89 ? 45 LEU H CD2 1 ATOM 3962 N N . GLU C 3 46 ? -20.912 -19.341 7.298 1.00 84.74 ? 46 GLU H N 1 ATOM 3963 C CA . GLU C 3 46 ? -21.644 -20.603 7.525 1.00 84.74 ? 46 GLU H CA 1 ATOM 3964 C C . GLU C 3 46 ? -23.088 -20.133 7.646 1.00 84.74 ? 46 GLU H C 1 ATOM 3965 O O . GLU C 3 46 ? -23.374 -19.210 8.408 1.00 84.74 ? 46 GLU H O 1 ATOM 3966 C CB . GLU C 3 46 ? -21.186 -21.242 8.833 1.00 75.40 ? 46 GLU H CB 1 ATOM 3967 C CG . GLU C 3 46 ? -21.801 -22.581 9.257 1.00 75.40 ? 46 GLU H CG 1 ATOM 3968 C CD . GLU C 3 46 ? -21.226 -23.134 10.642 1.00 75.40 ? 46 GLU H CD 1 ATOM 3969 O OE1 . GLU C 3 46 ? -20.348 -22.532 11.347 1.00 75.40 ? 46 GLU H OE1 1 ATOM 3970 O OE2 . GLU C 3 46 ? -21.596 -24.264 10.998 1.00 75.40 ? 46 GLU H OE2 1 ATOM 3971 N N . TRP C 3 47 ? -24.009 -20.743 6.922 1.00 70.30 ? 47 TRP H N 1 ATOM 3972 C CA . TRP C 3 47 ? -25.372 -20.279 7.009 1.00 70.30 ? 47 TRP H CA 1 ATOM 3973 C C . TRP C 3 47 ? -26.138 -21.175 7.895 1.00 70.30 ? 47 TRP H C 1 ATOM 3974 O O . TRP C 3 47 ? -26.208 -22.358 7.613 1.00 70.30 ? 47 TRP H O 1 ATOM 3975 C CB . TRP C 3 47 ? -25.928 -20.356 5.599 1.00 75.07 ? 47 TRP H CB 1 ATOM 3976 C CG . TRP C 3 47 ? -27.429 -20.152 5.376 1.00 75.07 ? 47 TRP H CG 1 ATOM 3977 C CD1 . TRP C 3 47 ? -28.126 -18.989 5.316 1.00 75.07 ? 47 TRP H CD1 1 ATOM 3978 C CD2 . TRP C 3 47 ? -28.399 -21.195 5.363 1.00 75.07 ? 47 TRP H CD2 1 ATOM 3979 N NE1 . TRP C 3 47 ? -29.472 -19.249 5.299 1.00 75.07 ? 47 TRP H NE1 1 ATOM 3980 C CE2 . TRP C 3 47 ? -29.658 -20.600 5.338 1.00 75.07 ? 47 TRP H CE2 1 ATOM 3981 C CE3 . TRP C 3 47 ? -28.311 -22.576 5.378 1.00 75.07 ? 47 TRP H CE3 1 ATOM 3982 C CZ2 . TRP C 3 47 ? -30.815 -21.328 5.346 1.00 75.07 ? 47 TRP H CZ2 1 ATOM 3983 C CZ3 . TRP C 3 47 ? -29.443 -23.292 5.375 1.00 75.07 ? 47 TRP H CZ3 1 ATOM 3984 C CH2 . TRP C 3 47 ? -30.692 -22.671 5.365 1.00 75.07 ? 47 TRP H CH2 1 ATOM 3985 N N . MET C 3 48 ? -26.669 -20.609 8.976 1.00 61.36 ? 48 MET H N 1 ATOM 3986 C CA . MET C 3 48 ? -27.523 -21.266 9.977 1.00 61.36 ? 48 MET H CA 1 ATOM 3987 C C . MET C 3 48 ? -28.913 -21.688 9.596 1.00 61.36 ? 48 MET H C 1 ATOM 3988 O O . MET C 3 48 ? -29.376 -22.742 10.007 1.00 61.36 ? 48 MET H O 1 ATOM 3989 C CB . MET C 3 48 ? -27.584 -20.367 11.177 1.00 75.12 ? 48 MET H CB 1 ATOM 3990 C CG . MET C 3 48 ? -26.303 -20.320 11.873 1.00 75.12 ? 48 MET H CG 1 ATOM 3991 S SD . MET C 3 48 ? -26.541 -19.272 13.180 1.00 75.12 ? 48 MET H SD 1 ATOM 3992 C CE . MET C 3 48 ? -27.557 -20.028 14.184 1.00 75.12 ? 48 MET H CE 1 ATOM 3993 N N . GLY C 3 49 ? -29.583 -20.817 8.811 1.00 92.37 ? 49 GLY H N 1 ATOM 3994 C CA . GLY C 3 49 ? -30.967 -21.009 8.355 1.00 92.37 ? 49 GLY H CA 1 ATOM 3995 C C . GLY C 3 49 ? -31.674 -19.780 7.768 1.00 92.37 ? 49 GLY H C 1 ATOM 3996 O O . GLY C 3 49 ? -31.110 -18.716 7.581 1.00 92.37 ? 49 GLY H O 1 ATOM 3997 N N . GLY C 3 50 ? -32.938 -19.958 7.427 1.00 95.67 ? 50 GLY H N 1 ATOM 3998 C CA . GLY C 3 50 ? -33.764 -18.880 6.893 1.00 95.67 ? 50 GLY H CA 1 ATOM 3999 C C . GLY C 3 50 ? -34.949 -19.488 6.176 1.00 95.67 ? 50 GLY H C 1 ATOM 4000 O O . GLY C 3 50 ? -35.063 -20.694 6.103 1.00 95.67 ? 50 GLY H O 1 ATOM 4001 N N . PHE C 3 51 ? -35.827 -18.684 5.618 1.00 73.12 ? 51 PHE H N 1 ATOM 4002 C CA . PHE C 3 51 ? -36.960 -19.242 4.863 1.00 73.12 ? 51 PHE H CA 1 ATOM 4003 C C . PHE C 3 51 ? -36.696 -19.944 3.541 1.00 73.12 ? 51 PHE H C 1 ATOM 4004 O O . PHE C 3 51 ? -35.829 -19.534 2.768 1.00 73.12 ? 51 PHE H O 1 ATOM 4005 C CB . PHE C 3 51 ? -38.096 -18.208 4.799 1.00 107.94 ? 51 PHE H CB 1 ATOM 4006 C CG . PHE C 3 51 ? -39.279 -18.664 4.049 1.00 107.94 ? 51 PHE H CG 1 ATOM 4007 C CD1 . PHE C 3 51 ? -40.311 -19.336 4.649 1.00 107.94 ? 51 PHE H CD1 1 ATOM 4008 C CD2 . PHE C 3 51 ? -39.456 -18.225 2.766 1.00 107.94 ? 51 PHE H CD2 1 ATOM 4009 C CE1 . PHE C 3 51 ? -41.515 -19.569 3.983 1.00 107.94 ? 51 PHE H CE1 1 ATOM 4010 C CE2 . PHE C 3 51 ? -40.634 -18.438 2.094 1.00 107.94 ? 51 PHE H CE2 1 ATOM 4011 C CZ . PHE C 3 51 ? -41.671 -19.115 2.702 1.00 107.94 ? 51 PHE H CZ 1 ATOM 4012 N N . GLY C 3 52 ? -37.423 -21.047 3.333 1.00 84.29 ? 52 GLY H N 1 ATOM 4013 C CA . GLY C 3 52 ? -37.250 -21.880 2.143 1.00 84.29 ? 52 GLY H CA 1 ATOM 4014 C C . GLY C 3 52 ? -38.461 -22.289 1.307 1.00 84.29 ? 52 GLY H C 1 ATOM 4015 O O . GLY C 3 52 ? -39.556 -22.016 1.698 1.00 84.29 ? 52 GLY H O 1 ATOM 4016 N N . PRO C 3 53 ? -38.275 -22.880 0.109 1.00 82.60 ? 53 PRO H N 1 ATOM 4017 C CA . PRO C 3 53 ? -39.342 -23.346 -0.802 1.00 82.60 ? 53 PRO H CA 1 ATOM 4018 C C . PRO C 3 53 ? -40.311 -24.368 -0.178 1.00 82.60 ? 53 PRO H C 1 ATOM 4019 O O . PRO C 3 53 ? -41.147 -24.939 -0.849 1.00 82.60 ? 53 PRO H O 1 ATOM 4020 C CB . PRO C 3 53 ? -38.561 -23.947 -1.985 1.00 141.50 ? 53 PRO H CB 1 ATOM 4021 C CG . PRO C 3 53 ? -37.344 -23.076 -2.074 1.00 141.50 ? 53 PRO H CG 1 ATOM 4022 C CD . PRO C 3 53 ? -36.960 -22.971 -0.577 1.00 141.50 ? 53 PRO H CD 1 ATOM 4023 N N . GLU C 3 54 ? -40.066 -24.708 1.077 1.00 74.81 ? 54 GLU H N 1 ATOM 4024 C CA . GLU C 3 54 ? -40.977 -25.512 1.899 1.00 74.81 ? 54 GLU H CA 1 ATOM 4025 C C . GLU C 3 54 ? -41.601 -24.413 2.758 1.00 74.81 ? 54 GLU H C 1 ATOM 4026 O O . GLU C 3 54 ? -40.912 -23.681 3.454 1.00 74.81 ? 54 GLU H O 1 ATOM 4027 C CB . GLU C 3 54 ? -40.180 -26.517 2.691 1.00 115.09 ? 54 GLU H CB 1 ATOM 4028 C CG . GLU C 3 54 ? -41.010 -27.384 3.559 1.00 115.09 ? 54 GLU H CG 1 ATOM 4029 C CD . GLU C 3 54 ? -40.150 -28.361 4.319 1.00 115.09 ? 54 GLU H CD 1 ATOM 4030 O OE1 . GLU C 3 54 ? -38.946 -28.451 3.952 1.00 115.09 ? 54 GLU H OE1 1 ATOM 4031 O OE2 . GLU C 3 54 ? -40.626 -28.935 5.344 1.00 115.09 ? 54 GLU H OE2 1 ATOM 4032 N N . GLU C 3 55 ? -42.910 -24.263 2.679 1.00 83.93 ? 55 GLU H N 1 ATOM 4033 C CA . GLU C 3 55 ? -43.585 -23.143 3.322 1.00 83.93 ? 55 GLU H CA 1 ATOM 4034 C C . GLU C 3 55 ? -43.609 -22.972 4.868 1.00 83.93 ? 55 GLU H C 1 ATOM 4035 O O . GLU C 3 55 ? -43.392 -21.850 5.338 1.00 83.93 ? 55 GLU H O 1 ATOM 4036 C CB . GLU C 3 55 ? -45.030 -23.145 2.777 1.00 140.70 ? 55 GLU H CB 1 ATOM 4037 C CG . GLU C 3 55 ? -45.288 -22.753 1.275 1.00 140.70 ? 55 GLU H CG 1 ATOM 4038 C CD . GLU C 3 55 ? -44.861 -21.367 0.835 1.00 140.70 ? 55 GLU H CD 1 ATOM 4039 O OE1 . GLU C 3 55 ? -45.316 -20.383 1.421 1.00 140.70 ? 55 GLU H OE1 1 ATOM 4040 O OE2 . GLU C 3 55 ? -44.117 -21.243 -0.157 1.00 140.70 ? 55 GLU H OE2 1 ATOM 4041 N N . ASN C 3 56 ? -43.777 -24.083 5.618 1.00 215.20 ? 56 ASN H N 1 ATOM 4042 C CA . ASN C 3 56 ? -43.931 -24.111 7.107 1.00 215.20 ? 56 ASN H CA 1 ATOM 4043 C C . ASN C 3 56 ? -42.647 -23.752 7.837 1.00 215.20 ? 56 ASN H C 1 ATOM 4044 O O . ASN C 3 56 ? -42.620 -23.431 9.032 1.00 215.20 ? 56 ASN H O 1 ATOM 4045 C CB . ASN C 3 56 ? -44.349 -25.493 7.662 1.00 127.17 ? 56 ASN H CB 1 ATOM 4046 C CG . ASN C 3 56 ? -43.255 -26.550 7.563 1.00 127.17 ? 56 ASN H CG 1 ATOM 4047 O OD1 . ASN C 3 56 ? -42.242 -26.466 8.289 1.00 127.17 ? 56 ASN H OD1 1 ATOM 4048 N ND2 . ASN C 3 56 ? -43.427 -27.525 6.676 1.00 127.17 ? 56 ASN H ND2 1 ATOM 4049 N N . GLU C 3 57 ? -41.567 -23.892 7.100 1.00 96.07 ? 57 GLU H N 1 ATOM 4050 C CA . GLU C 3 57 ? -40.269 -23.653 7.607 1.00 96.07 ? 57 GLU H CA 1 ATOM 4051 C C . GLU C 3 57 ? -39.629 -22.449 7.058 1.00 96.07 ? 57 GLU H C 1 ATOM 4052 O O . GLU C 3 57 ? -39.872 -21.982 5.968 1.00 96.07 ? 57 GLU H O 1 ATOM 4053 C CB . GLU C 3 57 ? -39.320 -24.910 7.543 1.00 140.35 ? 57 GLU H CB 1 ATOM 4054 C CG . GLU C 3 57 ? -39.658 -26.096 8.526 1.00 140.35 ? 57 GLU H CG 1 ATOM 4055 C CD . GLU C 3 57 ? -38.787 -27.357 8.368 1.00 140.35 ? 57 GLU H CD 1 ATOM 4056 O OE1 . GLU C 3 57 ? -37.624 -27.397 8.842 1.00 140.35 ? 57 GLU H OE1 1 ATOM 4057 O OE2 . GLU C 3 57 ? -39.313 -28.342 7.797 1.00 140.35 ? 57 GLU H OE2 1 ATOM 4058 N N . ILE C 3 58 ? -38.805 -21.989 7.957 1.00 102.74 ? 58 ILE H N 1 ATOM 4059 C CA . ILE C 3 58 ? -37.921 -20.873 7.968 1.00 102.74 ? 58 ILE H CA 1 ATOM 4060 C C . ILE C 3 58 ? -37.149 -22.138 8.342 1.00 102.74 ? 58 ILE H C 1 ATOM 4061 O O . ILE C 3 58 ? -37.552 -22.912 9.205 1.00 102.74 ? 58 ILE H O 1 ATOM 4062 C CB . ILE C 3 58 ? -38.267 -19.907 9.159 1.00 66.57 ? 58 ILE H CB 1 ATOM 4063 C CG1 . ILE C 3 58 ? -37.392 -18.637 9.060 1.00 66.57 ? 58 ILE H CG1 1 ATOM 4064 C CG2 . ILE C 3 58 ? -38.211 -20.644 10.478 1.00 66.57 ? 58 ILE H CG2 1 ATOM 4065 C CD1 . ILE C 3 58 ? -37.809 -17.522 10.005 1.00 66.57 ? 58 ILE H CD1 1 ATOM 4066 N N . ILE C 3 59 ? -36.032 -22.360 7.692 1.00 96.27 ? 59 ILE H N 1 ATOM 4067 C CA . ILE C 3 59 ? -35.404 -23.644 7.816 1.00 96.27 ? 59 ILE H CA 1 ATOM 4068 C C . ILE C 3 59 ? -33.940 -23.473 8.156 1.00 96.27 ? 59 ILE H C 1 ATOM 4069 O O . ILE C 3 59 ? -33.215 -22.603 7.663 1.00 96.27 ? 59 ILE H O 1 ATOM 4070 C CB . ILE C 3 59 ? -35.630 -24.450 6.491 1.00 70.62 ? 59 ILE H CB 1 ATOM 4071 C CG1 . ILE C 3 59 ? -34.830 -25.742 6.499 1.00 70.62 ? 59 ILE H CG1 1 ATOM 4072 C CG2 . ILE C 3 59 ? -35.352 -23.596 5.274 1.00 70.62 ? 59 ILE H CG2 1 ATOM 4073 C CD1 . ILE C 3 59 ? -35.076 -26.634 5.257 1.00 70.62 ? 59 ILE H CD1 1 ATOM 4074 N N . TYR C 3 60 ? -33.536 -24.365 9.044 1.00 75.35 ? 60 TYR H N 1 ATOM 4075 C CA . TYR C 3 60 ? -32.265 -24.367 9.714 1.00 75.35 ? 60 TYR H CA 1 ATOM 4076 C C . TYR C 3 60 ? -31.474 -25.512 9.171 1.00 75.35 ? 60 TYR H C 1 ATOM 4077 O O . TYR C 3 60 ? -32.024 -26.566 8.854 1.00 75.35 ? 60 TYR H O 1 ATOM 4078 C CB . TYR C 3 60 ? -32.547 -24.676 11.147 1.00 69.44 ? 60 TYR H CB 1 ATOM 4079 C CG . TYR C 3 60 ? -33.436 -23.700 11.811 1.00 69.44 ? 60 TYR H CG 1 ATOM 4080 C CD1 . TYR C 3 60 ? -33.079 -22.362 11.909 1.00 69.44 ? 60 TYR H CD1 1 ATOM 4081 C CD2 . TYR C 3 60 ? -34.634 -24.103 12.353 1.00 69.44 ? 60 TYR H CD2 1 ATOM 4082 C CE1 . TYR C 3 60 ? -33.916 -21.433 12.559 1.00 69.44 ? 60 TYR H CE1 1 ATOM 4083 C CE2 . TYR C 3 60 ? -35.480 -23.189 13.002 1.00 69.44 ? 60 TYR H CE2 1 ATOM 4084 C CZ . TYR C 3 60 ? -35.109 -21.855 13.100 1.00 69.44 ? 60 TYR H CZ 1 ATOM 4085 O OH . TYR C 3 60 ? -35.897 -20.940 13.747 1.00 69.44 ? 60 TYR H OH 1 ATOM 4086 N N . ALA C 3 61 ? -30.177 -25.282 9.057 1.00 87.25 ? 61 ALA H N 1 ATOM 4087 C CA . ALA C 3 61 ? -29.235 -26.253 8.521 1.00 87.25 ? 61 ALA H CA 1 ATOM 4088 C C . ALA C 3 61 ? -29.129 -27.290 9.605 1.00 87.25 ? 61 ALA H C 1 ATOM 4089 O O . ALA C 3 61 ? -29.497 -27.026 10.751 1.00 87.25 ? 61 ALA H O 1 ATOM 4090 C CB . ALA C 3 61 ? -27.939 -25.636 8.219 1.00 37.88 ? 61 ALA H CB 1 ATOM 4091 N N . GLN C 3 62 ? -28.651 -28.469 9.235 1.00 122.92 ? 62 GLN H N 1 ATOM 4092 C CA . GLN C 3 62 ? -28.623 -29.664 10.073 1.00 122.92 ? 62 GLN H CA 1 ATOM 4093 C C . GLN C 3 62 ? -27.836 -29.601 11.393 1.00 122.92 ? 62 GLN H C 1 ATOM 4094 O O . GLN C 3 62 ? -28.284 -30.172 12.397 1.00 122.92 ? 62 GLN H O 1 ATOM 4095 C CB . GLN C 3 62 ? -28.443 -30.932 9.240 1.00 151.26 ? 62 GLN H CB 1 ATOM 4096 C CG . GLN C 3 62 ? -28.407 -32.204 10.054 1.00 151.26 ? 62 GLN H CG 1 ATOM 4097 C CD . GLN C 3 62 ? -28.227 -33.423 9.182 1.00 151.26 ? 62 GLN H CD 1 ATOM 4098 O OE1 . GLN C 3 62 ? -27.340 -33.471 8.340 1.00 151.26 ? 62 GLN H OE1 1 ATOM 4099 N NE2 . GLN C 3 62 ? -29.098 -34.410 9.362 1.00 151.26 ? 62 GLN H NE2 1 ATOM 4100 N N . LYS C 3 63 ? -26.671 -28.953 11.400 1.00 117.64 ? 63 LYS H N 1 ATOM 4101 C CA . LYS C 3 63 ? -25.816 -28.875 12.589 1.00 117.64 ? 63 LYS H CA 1 ATOM 4102 C C . LYS C 3 63 ? -26.606 -28.193 13.697 1.00 117.64 ? 63 LYS H C 1 ATOM 4103 O O . LYS C 3 63 ? -26.519 -28.577 14.865 1.00 117.64 ? 63 LYS H O 1 ATOM 4104 C CB . LYS C 3 63 ? -24.542 -28.044 12.412 1.00 90.31 ? 63 LYS H CB 1 ATOM 4105 C CG . LYS C 3 63 ? -23.473 -28.631 11.518 1.00 90.31 ? 63 LYS H CG 1 ATOM 4106 C CD . LYS C 3 63 ? -22.302 -27.659 11.475 1.00 90.31 ? 63 LYS H CD 1 ATOM 4107 C CE . LYS C 3 63 ? -21.180 -28.136 10.617 1.00 90.31 ? 63 LYS H CE 1 ATOM 4108 N NZ . LYS C 3 63 ? -20.084 -27.199 10.858 1.00 90.31 ? 63 LYS H NZ 1 ATOM 4109 N N . PHE C 3 64 ? -27.352 -27.183 13.333 1.00 106.12 ? 64 PHE H N 1 ATOM 4110 C CA . PHE C 3 64 ? -28.133 -26.364 14.235 1.00 106.12 ? 64 PHE H CA 1 ATOM 4111 C C . PHE C 3 64 ? -29.575 -26.918 14.468 1.00 106.12 ? 64 PHE H C 1 ATOM 4112 O O . PHE C 3 64 ? -30.331 -26.277 15.191 1.00 106.12 ? 64 PHE H O 1 ATOM 4113 C CB . PHE C 3 64 ? -28.305 -25.036 13.585 1.00 74.71 ? 64 PHE H CB 1 ATOM 4114 C CG . PHE C 3 64 ? -27.103 -24.309 13.431 1.00 74.71 ? 64 PHE H CG 1 ATOM 4115 C CD1 . PHE C 3 64 ? -26.370 -24.463 12.296 1.00 74.71 ? 64 PHE H CD1 1 ATOM 4116 C CD2 . PHE C 3 64 ? -26.763 -23.371 14.329 1.00 74.71 ? 64 PHE H CD2 1 ATOM 4117 C CE1 . PHE C 3 64 ? -25.285 -23.684 12.047 1.00 74.71 ? 64 PHE H CE1 1 ATOM 4118 C CE2 . PHE C 3 64 ? -25.676 -22.573 14.091 1.00 74.71 ? 64 PHE H CE2 1 ATOM 4119 C CZ . PHE C 3 64 ? -24.922 -22.729 12.938 1.00 74.71 ? 64 PHE H CZ 1 ATOM 4120 N N . GLN C 3 65 ? -29.995 -28.049 13.880 1.00 100.52 ? 65 GLN H N 1 ATOM 4121 C CA . GLN C 3 65 ? -31.413 -28.414 14.019 1.00 100.52 ? 65 GLN H CA 1 ATOM 4122 C C . GLN C 3 65 ? -31.988 -28.642 15.409 1.00 100.52 ? 65 GLN H C 1 ATOM 4123 O O . GLN C 3 65 ? -33.099 -28.176 15.641 1.00 100.52 ? 65 GLN H O 1 ATOM 4124 C CB . GLN C 3 65 ? -31.703 -29.806 13.439 1.00 74.48 ? 65 GLN H CB 1 ATOM 4125 C CG . GLN C 3 65 ? -31.698 -30.219 11.952 1.00 74.48 ? 65 GLN H CG 1 ATOM 4126 C CD . GLN C 3 65 ? -32.842 -29.627 11.206 1.00 74.48 ? 65 GLN H CD 1 ATOM 4127 O OE1 . GLN C 3 65 ? -33.897 -29.365 11.815 1.00 74.48 ? 65 GLN H OE1 1 ATOM 4128 N NE2 . GLN C 3 65 ? -32.715 -29.512 9.859 1.00 74.48 ? 65 GLN H NE2 1 ATOM 4129 N N . GLY C 3 66 ? -31.294 -29.279 16.351 1.00 96.59 ? 66 GLY H N 1 ATOM 4130 C CA . GLY C 3 66 ? -31.949 -29.450 17.645 1.00 96.59 ? 66 GLY H CA 1 ATOM 4131 C C . GLY C 3 66 ? -32.256 -28.170 18.415 1.00 96.59 ? 66 GLY H C 1 ATOM 4132 O O . GLY C 3 66 ? -33.339 -27.902 18.969 1.00 96.59 ? 66 GLY H O 1 ATOM 4133 N N . ARG C 3 67 ? -31.222 -27.360 18.389 1.00 120.60 ? 67 ARG H N 1 ATOM 4134 C CA . ARG C 3 67 ? -31.124 -26.092 19.063 1.00 120.60 ? 67 ARG H CA 1 ATOM 4135 C C . ARG C 3 67 ? -31.442 -24.699 18.583 1.00 120.60 ? 67 ARG H C 1 ATOM 4136 O O . ARG C 3 67 ? -31.374 -23.781 19.386 1.00 120.60 ? 67 ARG H O 1 ATOM 4137 C CB . ARG C 3 67 ? -29.767 -26.053 19.749 1.00 83.59 ? 67 ARG H CB 1 ATOM 4138 C CG . ARG C 3 67 ? -28.646 -26.185 18.784 1.00 83.59 ? 67 ARG H CG 1 ATOM 4139 C CD . ARG C 3 67 ? -27.280 -26.393 19.399 1.00 83.59 ? 67 ARG H CD 1 ATOM 4140 N NE . ARG C 3 67 ? -26.356 -26.571 18.292 1.00 83.59 ? 67 ARG H NE 1 ATOM 4141 C CZ . ARG C 3 67 ? -25.046 -26.454 18.333 1.00 83.59 ? 67 ARG H CZ 1 ATOM 4142 N NH1 . ARG C 3 67 ? -24.434 -26.114 19.423 1.00 83.59 ? 67 ARG H NH1 1 ATOM 4143 N NH2 . ARG C 3 67 ? -24.335 -26.802 17.304 1.00 83.59 ? 67 ARG H NH2 1 ATOM 4144 N N . VAL C 3 68 ? -31.892 -24.470 17.366 1.00 87.46 ? 68 VAL H N 1 ATOM 4145 C CA . VAL C 3 68 ? -32.021 -23.055 17.035 1.00 87.46 ? 68 VAL H CA 1 ATOM 4146 C C . VAL C 3 68 ? -33.301 -22.567 16.504 1.00 87.46 ? 68 VAL H C 1 ATOM 4147 O O . VAL C 3 68 ? -33.922 -23.178 15.675 1.00 87.46 ? 68 VAL H O 1 ATOM 4148 C CB . VAL C 3 68 ? -30.959 -22.614 16.034 1.00 73.53 ? 68 VAL H CB 1 ATOM 4149 C CG1 . VAL C 3 68 ? -31.021 -23.439 14.805 1.00 73.53 ? 68 VAL H CG1 1 ATOM 4150 C CG2 . VAL C 3 68 ? -31.198 -21.194 15.663 1.00 73.53 ? 68 VAL H CG2 1 ATOM 4151 N N . SER C 3 69 ? -33.697 -21.446 17.091 1.00 68.30 ? 69 SER H N 1 ATOM 4152 C CA . SER C 3 69 ? -34.943 -20.767 16.781 1.00 68.30 ? 69 SER H CA 1 ATOM 4153 C C . SER C 3 69 ? -34.748 -19.344 16.272 1.00 68.30 ? 69 SER H C 1 ATOM 4154 O O . SER C 3 69 ? -34.105 -18.539 16.959 1.00 68.30 ? 69 SER H O 1 ATOM 4155 C CB . SER C 3 69 ? -35.813 -20.696 18.011 1.00 136.88 ? 69 SER H CB 1 ATOM 4156 O OG . SER C 3 69 ? -36.912 -19.847 17.743 1.00 136.88 ? 69 SER H OG 1 ATOM 4157 N N . MET C 3 70 ? -35.402 -19.024 15.132 1.00 69.36 ? 70 MET H N 1 ATOM 4158 C CA . MET C 3 70 ? -35.303 -17.734 14.423 1.00 69.36 ? 70 MET H CA 1 ATOM 4159 C C . MET C 3 70 ? -36.682 -17.094 14.375 1.00 69.36 ? 70 MET H C 1 ATOM 4160 O O . MET C 3 70 ? -37.706 -17.800 14.414 1.00 69.36 ? 70 MET H O 1 ATOM 4161 C CB . MET C 3 70 ? -34.747 -17.972 13.017 1.00 97.90 ? 70 MET H CB 1 ATOM 4162 C CG . MET C 3 70 ? -33.293 -18.374 13.005 1.00 97.90 ? 70 MET H CG 1 ATOM 4163 S SD . MET C 3 70 ? -32.584 -18.668 11.385 1.00 97.90 ? 70 MET H SD 1 ATOM 4164 C CE . MET C 3 70 ? -32.560 -17.117 10.788 1.00 97.90 ? 70 MET H CE 1 ATOM 4165 N N . THR C 3 71 ? -36.719 -15.784 14.568 1.00 107.46 ? 71 THR H N 1 ATOM 4166 C CA . THR C 3 71 ? -37.986 -15.060 14.541 1.00 107.46 ? 71 THR H CA 1 ATOM 4167 C C . THR C 3 71 ? -38.016 -13.690 13.870 1.00 107.46 ? 71 THR H C 1 ATOM 4168 O O . THR C 3 71 ? -36.955 -13.041 13.800 1.00 107.46 ? 71 THR H O 1 ATOM 4169 C CB . THR C 3 71 ? -38.536 -14.890 15.970 1.00 109.97 ? 71 THR H CB 1 ATOM 4170 O OG1 . THR C 3 71 ? -38.529 -16.147 16.637 1.00 109.97 ? 71 THR H OG1 1 ATOM 4171 C CG2 . THR C 3 71 ? -39.950 -14.361 15.956 1.00 109.97 ? 71 THR H CG2 1 ATOM 4172 N N . GLU C 3 72 ? -39.157 -13.287 13.293 1.00 79.11 ? 72 GLU H N 1 ATOM 4173 C CA . GLU C 3 72 ? -39.278 -11.906 12.842 1.00 79.11 ? 72 GLU H CA 1 ATOM 4174 C C . GLU C 3 72 ? -40.637 -11.439 13.443 1.00 79.11 ? 72 GLU H C 1 ATOM 4175 O O . GLU C 3 72 ? -41.583 -12.155 13.276 1.00 79.11 ? 72 GLU H O 1 ATOM 4176 C CB . GLU C 3 72 ? -39.352 -11.934 11.334 1.00 51.56 ? 72 GLU H CB 1 ATOM 4177 C CG . GLU C 3 72 ? -38.048 -12.327 10.709 1.00 51.56 ? 72 GLU H CG 1 ATOM 4178 C CD . GLU C 3 72 ? -38.153 -12.467 9.220 1.00 51.56 ? 72 GLU H CD 1 ATOM 4179 O OE1 . GLU C 3 72 ? -39.157 -11.982 8.677 1.00 51.56 ? 72 GLU H OE1 1 ATOM 4180 O OE2 . GLU C 3 72 ? -37.318 -13.186 8.585 1.00 51.56 ? 72 GLU H OE2 1 ATOM 4181 N N . ASP C 3 73 ? -40.792 -10.291 14.103 1.00 74.94 ? 73 ASP H N 1 ATOM 4182 C CA . ASP C 3 73 ? -42.155 -9.874 14.472 1.00 74.94 ? 73 ASP H CA 1 ATOM 4183 C C . ASP C 3 73 ? -42.412 -8.881 13.419 1.00 74.94 ? 73 ASP H C 1 ATOM 4184 O O . ASP C 3 73 ? -41.617 -7.961 13.301 1.00 74.94 ? 73 ASP H O 1 ATOM 4185 C CB . ASP C 3 73 ? -42.393 -9.129 15.819 1.00 124.51 ? 73 ASP H CB 1 ATOM 4186 C CG . ASP C 3 73 ? -42.220 -9.980 17.078 1.00 124.51 ? 73 ASP H CG 1 ATOM 4187 O OD1 . ASP C 3 73 ? -42.018 -9.393 18.166 1.00 124.51 ? 73 ASP H OD1 1 ATOM 4188 O OD2 . ASP C 3 73 ? -42.372 -11.217 17.027 1.00 124.51 ? 73 ASP H OD2 1 ATOM 4189 N N . THR C 3 74 ? -43.440 -9.070 12.590 1.00 101.97 ? 74 THR H N 1 ATOM 4190 C CA . THR C 3 74 ? -43.644 -8.061 11.584 1.00 101.97 ? 74 THR H CA 1 ATOM 4191 C C . THR C 3 74 ? -43.901 -6.688 12.191 1.00 101.97 ? 74 THR H C 1 ATOM 4192 O O . THR C 3 74 ? -43.461 -5.726 11.635 1.00 101.97 ? 74 THR H O 1 ATOM 4193 C CB . THR C 3 74 ? -44.742 -8.519 10.645 1.00 76.57 ? 74 THR H CB 1 ATOM 4194 O OG1 . THR C 3 74 ? -45.626 -9.327 11.420 1.00 76.57 ? 74 THR H OG1 1 ATOM 4195 C CG2 . THR C 3 74 ? -44.222 -9.295 9.419 1.00 76.57 ? 74 THR H CG2 1 ATOM 4196 N N . SER C 3 75 ? -44.674 -6.561 13.264 1.00 94.36 ? 75 SER H N 1 ATOM 4197 C CA . SER C 3 75 ? -44.845 -5.282 14.002 1.00 94.36 ? 75 SER H CA 1 ATOM 4198 C C . SER C 3 75 ? -43.765 -4.437 14.746 1.00 94.36 ? 75 SER H C 1 ATOM 4199 O O . SER C 3 75 ? -43.777 -3.226 14.679 1.00 94.36 ? 75 SER H O 1 ATOM 4200 C CB . SER C 3 75 ? -46.057 -5.404 14.941 1.00 163.64 ? 75 SER H CB 1 ATOM 4201 O OG . SER C 3 75 ? -47.278 -5.456 14.209 1.00 163.64 ? 75 SER H OG 1 ATOM 4202 N N . THR C 3 76 ? -42.834 -5.080 15.455 1.00 66.39 ? 76 THR H N 1 ATOM 4203 C CA . THR C 3 76 ? -41.796 -4.386 16.264 1.00 66.39 ? 76 THR H CA 1 ATOM 4204 C C . THR C 3 76 ? -40.638 -4.124 15.317 1.00 66.39 ? 76 THR H C 1 ATOM 4205 O O . THR C 3 76 ? -39.690 -3.427 15.641 1.00 66.39 ? 76 THR H O 1 ATOM 4206 C CB . THR C 3 76 ? -41.156 -5.317 17.229 1.00 88.77 ? 76 THR H CB 1 ATOM 4207 O OG1 . THR C 3 76 ? -40.343 -6.234 16.482 1.00 88.77 ? 76 THR H OG1 1 ATOM 4208 C CG2 . THR C 3 76 ? -42.241 -6.185 17.918 1.00 88.77 ? 76 THR H CG2 1 ATOM 4209 N N . ASN C 3 77 ? -40.772 -4.751 14.150 1.00 83.76 ? 77 ASN H N 1 ATOM 4210 C CA . ASN C 3 77 ? -39.862 -4.796 13.008 1.00 83.76 ? 77 ASN H CA 1 ATOM 4211 C C . ASN C 3 77 ? -38.431 -5.155 13.378 1.00 83.76 ? 77 ASN H C 1 ATOM 4212 O O . ASN C 3 77 ? -37.523 -4.417 13.107 1.00 83.76 ? 77 ASN H O 1 ATOM 4213 C CB . ASN C 3 77 ? -39.939 -3.550 12.078 1.00 42.81 ? 77 ASN H CB 1 ATOM 4214 C CG . ASN C 3 77 ? -39.238 -3.818 10.718 1.00 42.81 ? 77 ASN H CG 1 ATOM 4215 O OD1 . ASN C 3 77 ? -38.083 -3.616 10.567 1.00 42.81 ? 77 ASN H OD1 1 ATOM 4216 N ND2 . ASN C 3 77 ? -39.965 -4.274 9.759 1.00 42.81 ? 77 ASN H ND2 1 ATOM 4217 N N . THR C 3 78 ? -38.284 -6.231 14.134 1.00 64.56 ? 78 THR H N 1 ATOM 4218 C CA . THR C 3 78 ? -36.996 -6.763 14.566 1.00 64.56 ? 78 THR H CA 1 ATOM 4219 C C . THR C 3 78 ? -37.011 -8.289 14.485 1.00 64.56 ? 78 THR H C 1 ATOM 4220 O O . THR C 3 78 ? -38.038 -8.855 14.403 1.00 64.56 ? 78 THR H O 1 ATOM 4221 C CB . THR C 3 78 ? -36.722 -6.323 15.989 1.00 42.07 ? 78 THR H CB 1 ATOM 4222 O OG1 . THR C 3 78 ? -37.812 -6.712 16.813 1.00 42.07 ? 78 THR H OG1 1 ATOM 4223 C CG2 . THR C 3 78 ? -36.557 -4.877 16.071 1.00 42.07 ? 78 THR H CG2 1 ATOM 4224 N N . ALA C 3 79 ? -35.883 -8.959 14.440 1.00 49.03 ? 79 ALA H N 1 ATOM 4225 C CA . ALA C 3 79 ? -35.844 -10.424 14.392 1.00 49.03 ? 79 ALA H CA 1 ATOM 4226 C C . ALA C 3 79 ? -34.937 -11.040 15.431 1.00 49.03 ? 79 ALA H C 1 ATOM 4227 O O . ALA C 3 79 ? -33.830 -10.622 15.635 1.00 49.03 ? 79 ALA H O 1 ATOM 4228 C CB . ALA C 3 79 ? -35.401 -10.869 13.091 1.00 12.02 ? 79 ALA H CB 1 ATOM 4229 N N . TYR C 3 80 ? -35.343 -12.130 16.022 1.00 77.58 ? 80 TYR H N 1 ATOM 4230 C CA . TYR C 3 80 ? -34.561 -12.665 17.106 1.00 77.58 ? 80 TYR H CA 1 ATOM 4231 C C . TYR C 3 80 ? -34.074 -14.053 16.830 1.00 77.58 ? 80 TYR H C 1 ATOM 4232 O O . TYR C 3 80 ? -34.824 -14.871 16.349 1.00 77.58 ? 80 TYR H O 1 ATOM 4233 C CB . TYR C 3 80 ? -35.474 -12.723 18.304 1.00 83.49 ? 80 TYR H CB 1 ATOM 4234 C CG . TYR C 3 80 ? -35.831 -11.398 18.855 1.00 83.49 ? 80 TYR H CG 1 ATOM 4235 C CD1 . TYR C 3 80 ? -35.082 -10.811 19.816 1.00 83.49 ? 80 TYR H CD1 1 ATOM 4236 C CD2 . TYR C 3 80 ? -36.931 -10.745 18.418 1.00 83.49 ? 80 TYR H CD2 1 ATOM 4237 C CE1 . TYR C 3 80 ? -35.414 -9.609 20.342 1.00 83.49 ? 80 TYR H CE1 1 ATOM 4238 C CE2 . TYR C 3 80 ? -37.268 -9.539 18.929 1.00 83.49 ? 80 TYR H CE2 1 ATOM 4239 C CZ . TYR C 3 80 ? -36.498 -8.977 19.901 1.00 83.49 ? 80 TYR H CZ 1 ATOM 4240 O OH . TYR C 3 80 ? -36.800 -7.773 20.466 1.00 83.49 ? 80 TYR H OH 1 ATOM 4241 N N . MET C 3 81 ? -32.844 -14.353 17.206 1.00 82.91 ? 81 MET H N 1 ATOM 4242 C CA . MET C 3 81 ? -32.339 -15.695 16.975 1.00 82.91 ? 81 MET H CA 1 ATOM 4243 C C . MET C 3 81 ? -31.800 -16.348 18.258 1.00 82.91 ? 81 MET H C 1 ATOM 4244 O O . MET C 3 81 ? -30.970 -15.728 18.922 1.00 82.91 ? 81 MET H O 1 ATOM 4245 C CB . MET C 3 81 ? -31.229 -15.586 15.868 1.00 75.31 ? 81 MET H CB 1 ATOM 4246 C CG . MET C 3 81 ? -30.713 -16.878 15.288 1.00 75.31 ? 81 MET H CG 1 ATOM 4247 S SD . MET C 3 81 ? -29.717 -17.788 16.435 1.00 75.31 ? 81 MET H SD 1 ATOM 4248 C CE . MET C 3 81 ? -28.029 -17.152 16.173 1.00 75.31 ? 81 MET H CE 1 ATOM 4249 N N . GLU C 3 82 ? -32.214 -17.590 18.592 1.00 52.63 ? 82 GLU H N 1 ATOM 4250 C CA . GLU C 3 82 ? -31.598 -18.266 19.726 1.00 52.63 ? 82 GLU H CA 1 ATOM 4251 C C . GLU C 3 82 ? -30.930 -19.541 19.289 1.00 52.63 ? 82 GLU H C 1 ATOM 4252 O O . GLU C 3 82 ? -31.506 -20.349 18.581 1.00 52.63 ? 82 GLU H O 1 ATOM 4253 C CB . GLU C 3 82 ? -32.522 -18.696 20.900 1.00 81.96 ? 82 GLU H CB 1 ATOM 4254 C CG . GLU C 3 82 ? -33.136 -17.626 21.803 1.00 81.96 ? 82 GLU H CG 1 ATOM 4255 C CD . GLU C 3 82 ? -34.023 -18.231 22.914 1.00 81.96 ? 82 GLU H CD 1 ATOM 4256 O OE1 . GLU C 3 82 ? -35.249 -18.467 22.741 1.00 81.96 ? 82 GLU H OE1 1 ATOM 4257 O OE2 . GLU C 3 82 ? -33.414 -18.486 24.012 1.00 81.96 ? 82 GLU H OE2 1 ATOM 4258 N N . LEU C 3 83 ? -29.718 -19.724 19.791 1.00 92.74 ? 83 LEU H N 1 ATOM 4259 C CA . LEU C 3 83 ? -28.926 -20.925 19.568 1.00 92.74 ? 83 LEU H CA 1 ATOM 4260 C C . LEU C 3 83 ? -28.806 -21.313 21.030 1.00 92.74 ? 83 LEU H C 1 ATOM 4261 O O . LEU C 3 83 ? -28.486 -20.453 21.836 1.00 92.74 ? 83 LEU H O 1 ATOM 4262 C CB . LEU C 3 83 ? -27.572 -20.603 19.003 1.00 40.04 ? 83 LEU H CB 1 ATOM 4263 C CG . LEU C 3 83 ? -26.674 -21.790 18.737 1.00 40.04 ? 83 LEU H CG 1 ATOM 4264 C CD1 . LEU C 3 83 ? -27.322 -22.600 17.618 1.00 40.04 ? 83 LEU H CD1 1 ATOM 4265 C CD2 . LEU C 3 83 ? -25.337 -21.324 18.242 1.00 40.04 ? 83 LEU H CD2 1 ATOM 4266 N N . SER C 3 84 ? -29.066 -22.570 21.380 1.00 114.86 ? 84 SER H N 1 ATOM 4267 C CA . SER C 3 84 ? -29.095 -23.030 22.777 1.00 114.86 ? 84 SER H CA 1 ATOM 4268 C C . SER C 3 84 ? -28.233 -24.252 22.828 1.00 114.86 ? 84 SER H C 1 ATOM 4269 O O . SER C 3 84 ? -27.855 -24.763 21.774 1.00 114.86 ? 84 SER H O 1 ATOM 4270 C CB . SER C 3 84 ? -30.514 -23.419 23.214 1.00 178.73 ? 84 SER H CB 1 ATOM 4271 O OG . SER C 3 84 ? -30.940 -24.606 22.572 1.00 178.73 ? 84 SER H OG 1 ATOM 4272 N N . SER C 3 85 ? -27.929 -24.745 24.030 1.00 88.47 ? 85 SER H N 1 ATOM 4273 C CA . SER C 3 85 ? -27.032 -25.887 24.096 1.00 88.47 ? 85 SER H CA 1 ATOM 4274 C C . SER C 3 85 ? -25.635 -25.648 23.450 1.00 88.47 ? 85 SER H C 1 ATOM 4275 O O . SER C 3 85 ? -25.200 -26.418 22.587 1.00 88.47 ? 85 SER H O 1 ATOM 4276 C CB . SER C 3 85 ? -27.695 -27.093 23.429 1.00 107.40 ? 85 SER H CB 1 ATOM 4277 O OG . SER C 3 85 ? -28.423 -27.848 24.362 1.00 107.40 ? 85 SER H OG 1 ATOM 4278 N N . LEU C 3 86 ? -24.997 -24.533 23.822 1.00 91.11 ? 86 LEU H N 1 ATOM 4279 C CA . LEU C 3 86 ? -23.652 -24.132 23.345 1.00 91.11 ? 86 LEU H CA 1 ATOM 4280 C C . LEU C 3 86 ? -22.388 -24.987 23.566 1.00 91.11 ? 86 LEU H C 1 ATOM 4281 O O . LEU C 3 86 ? -22.175 -25.670 24.551 1.00 91.11 ? 86 LEU H O 1 ATOM 4282 C CB . LEU C 3 86 ? -23.322 -22.674 23.740 1.00 74.25 ? 86 LEU H CB 1 ATOM 4283 C CG . LEU C 3 86 ? -23.874 -21.466 22.977 1.00 74.25 ? 86 LEU H CG 1 ATOM 4284 C CD1 . LEU C 3 86 ? -25.285 -21.399 23.225 1.00 74.25 ? 86 LEU H CD1 1 ATOM 4285 C CD2 . LEU C 3 86 ? -23.313 -20.143 23.500 1.00 74.25 ? 86 LEU H CD2 1 ATOM 4286 N N . ARG C 3 87 ? -21.620 -24.963 22.503 1.00 70.05 ? 87 ARG H N 1 ATOM 4287 C CA . ARG C 3 87 ? -20.357 -25.606 22.192 1.00 70.05 ? 87 ARG H CA 1 ATOM 4288 C C . ARG C 3 87 ? -19.153 -24.686 22.110 1.00 70.05 ? 87 ARG H C 1 ATOM 4289 O O . ARG C 3 87 ? -19.263 -23.470 22.184 1.00 70.05 ? 87 ARG H O 1 ATOM 4290 C CB . ARG C 3 87 ? -20.407 -26.414 20.885 1.00 103.53 ? 87 ARG H CB 1 ATOM 4291 C CG . ARG C 3 87 ? -21.412 -27.563 20.837 1.00 103.53 ? 87 ARG H CG 1 ATOM 4292 C CD . ARG C 3 87 ? -20.917 -28.666 21.787 1.00 103.53 ? 87 ARG H CD 1 ATOM 4293 N NE . ARG C 3 87 ? -19.631 -29.247 21.332 1.00 103.53 ? 87 ARG H NE 1 ATOM 4294 C CZ . ARG C 3 87 ? -19.523 -30.272 20.486 1.00 103.53 ? 87 ARG H CZ 1 ATOM 4295 N NH1 . ARG C 3 87 ? -20.631 -30.832 20.004 1.00 103.53 ? 87 ARG H NH1 1 ATOM 4296 N NH2 . ARG C 3 87 ? -18.328 -30.734 20.133 1.00 103.53 ? 87 ARG H NH2 1 ATOM 4297 N N . SER C 3 88 ? -17.993 -25.299 22.219 1.00 113.08 ? 88 SER H N 1 ATOM 4298 C CA . SER C 3 88 ? -16.748 -24.583 22.084 1.00 113.08 ? 88 SER H CA 1 ATOM 4299 C C . SER C 3 88 ? -16.643 -23.929 20.700 1.00 113.08 ? 88 SER H C 1 ATOM 4300 O O . SER C 3 88 ? -16.213 -22.786 20.611 1.00 113.08 ? 88 SER H O 1 ATOM 4301 C CB . SER C 3 88 ? -15.606 -25.558 22.250 1.00 129.56 ? 88 SER H CB 1 ATOM 4302 O OG . SER C 3 88 ? -15.534 -25.994 23.590 1.00 129.56 ? 88 SER H OG 1 ATOM 4303 N N . GLU C 3 89 ? -17.083 -24.627 19.646 1.00 114.91 ? 89 GLU H N 1 ATOM 4304 C CA . GLU C 3 89 ? -17.006 -24.116 18.265 1.00 114.91 ? 89 GLU H CA 1 ATOM 4305 C C . GLU C 3 89 ? -17.934 -22.954 17.965 1.00 114.91 ? 89 GLU H C 1 ATOM 4306 O O . GLU C 3 89 ? -17.644 -22.126 17.097 1.00 114.91 ? 89 GLU H O 1 ATOM 4307 C CB . GLU C 3 89 ? -17.346 -25.133 17.183 1.00 209.82 ? 89 GLU H CB 1 ATOM 4308 C CG . GLU C 3 89 ? -18.768 -25.649 17.282 1.00 209.82 ? 89 GLU H CG 1 ATOM 4309 C CD . GLU C 3 89 ? -19.094 -26.654 16.203 1.00 209.82 ? 89 GLU H CD 1 ATOM 4310 O OE1 . GLU C 3 89 ? -18.370 -26.661 15.182 1.00 209.82 ? 89 GLU H OE1 1 ATOM 4311 O OE2 . GLU C 3 89 ? -20.050 -27.441 16.375 1.00 209.82 ? 89 GLU H OE2 1 ATOM 4312 N N . ASP C 3 90 ? -18.962 -22.789 18.776 1.00 72.83 ? 90 ASP H N 1 ATOM 4313 C CA . ASP C 3 90 ? -20.002 -21.833 18.466 1.00 72.83 ? 90 ASP H CA 1 ATOM 4314 C C . ASP C 3 90 ? -19.541 -20.408 18.544 1.00 72.83 ? 90 ASP H C 1 ATOM 4315 O O . ASP C 3 90 ? -20.177 -19.544 17.928 1.00 72.83 ? 90 ASP H O 1 ATOM 4316 C CB . ASP C 3 90 ? -21.235 -22.089 19.349 1.00 72.60 ? 90 ASP H CB 1 ATOM 4317 C CG . ASP C 3 90 ? -21.947 -23.366 18.980 1.00 72.60 ? 90 ASP H CG 1 ATOM 4318 O OD1 . ASP C 3 90 ? -22.698 -23.924 19.791 1.00 72.60 ? 90 ASP H OD1 1 ATOM 4319 O OD2 . ASP C 3 90 ? -21.811 -23.768 17.809 1.00 72.60 ? 90 ASP H OD2 1 ATOM 4320 N N . THR C 3 91 ? -18.443 -20.130 19.244 1.00 107.95 ? 91 THR H N 1 ATOM 4321 C CA . THR C 3 91 ? -18.035 -18.738 19.280 1.00 107.95 ? 91 THR H CA 1 ATOM 4322 C C . THR C 3 91 ? -17.826 -18.498 17.795 1.00 107.95 ? 91 THR H C 1 ATOM 4323 O O . THR C 3 91 ? -17.186 -19.274 17.087 1.00 107.95 ? 91 THR H O 1 ATOM 4324 C CB . THR C 3 91 ? -16.631 -18.562 19.882 1.00 84.73 ? 91 THR H CB 1 ATOM 4325 O OG1 . THR C 3 91 ? -15.697 -19.225 19.013 1.00 84.73 ? 91 THR H OG1 1 ATOM 4326 C CG2 . THR C 3 91 ? -16.510 -19.165 21.257 1.00 84.73 ? 91 THR H CG2 1 ATOM 4327 N N . ALA C 3 92 ? -18.315 -17.350 17.376 1.00 72.47 ? 92 ALA H N 1 ATOM 4328 C CA . ALA C 3 92 ? -18.281 -16.911 15.996 1.00 72.47 ? 92 ALA H CA 1 ATOM 4329 C C . ALA C 3 92 ? -18.949 -15.564 16.027 1.00 72.47 ? 92 ALA H C 1 ATOM 4330 O O . ALA C 3 92 ? -19.379 -15.094 17.086 1.00 72.47 ? 92 ALA H O 1 ATOM 4331 C CB . ALA C 3 92 ? -19.061 -17.842 15.107 1.00 112.66 ? 92 ALA H CB 1 ATOM 4332 N N . VAL C 3 93 ? -19.041 -14.948 14.863 1.00 68.03 ? 93 VAL H N 1 ATOM 4333 C CA . VAL C 3 93 ? -19.713 -13.685 14.790 1.00 68.03 ? 93 VAL H CA 1 ATOM 4334 C C . VAL C 3 93 ? -20.964 -14.048 14.028 1.00 68.03 ? 93 VAL H C 1 ATOM 4335 O O . VAL C 3 93 ? -20.922 -14.561 12.958 1.00 68.03 ? 93 VAL H O 1 ATOM 4336 C CB . VAL C 3 93 ? -18.945 -12.615 13.977 1.00 42.03 ? 93 VAL H CB 1 ATOM 4337 C CG1 . VAL C 3 93 ? -19.716 -11.307 13.945 1.00 42.03 ? 93 VAL H CG1 1 ATOM 4338 C CG2 . VAL C 3 93 ? -17.636 -12.345 14.602 1.00 42.03 ? 93 VAL H CG2 1 ATOM 4339 N N . TYR C 3 94 ? -22.085 -13.680 14.608 1.00 76.06 ? 94 TYR H N 1 ATOM 4340 C CA . TYR C 3 94 ? -23.395 -13.932 14.104 1.00 76.06 ? 94 TYR H CA 1 ATOM 4341 C C . TYR C 3 94 ? -23.836 -12.648 13.442 1.00 76.06 ? 94 TYR H C 1 ATOM 4342 O O . TYR C 3 94 ? -23.771 -11.552 14.002 1.00 76.06 ? 94 TYR H O 1 ATOM 4343 C CB . TYR C 3 94 ? -24.307 -14.330 15.278 1.00 59.21 ? 94 TYR H CB 1 ATOM 4344 C CG . TYR C 3 94 ? -24.000 -15.667 15.852 1.00 59.21 ? 94 TYR H CG 1 ATOM 4345 C CD1 . TYR C 3 94 ? -24.619 -16.773 15.353 1.00 59.21 ? 94 TYR H CD1 1 ATOM 4346 C CD2 . TYR C 3 94 ? -22.973 -15.853 16.748 1.00 59.21 ? 94 TYR H CD2 1 ATOM 4347 C CE1 . TYR C 3 94 ? -24.250 -18.009 15.699 1.00 59.21 ? 94 TYR H CE1 1 ATOM 4348 C CE2 . TYR C 3 94 ? -22.568 -17.132 17.106 1.00 59.21 ? 94 TYR H CE2 1 ATOM 4349 C CZ . TYR C 3 94 ? -23.220 -18.206 16.559 1.00 59.21 ? 94 TYR H CZ 1 ATOM 4350 O OH . TYR C 3 94 ? -22.799 -19.485 16.807 1.00 59.21 ? 94 TYR H OH 1 ATOM 4351 N N . TYR C 3 95 ? -24.329 -12.829 12.228 1.00 108.66 ? 95 TYR H N 1 ATOM 4352 C CA . TYR C 3 95 ? -24.747 -11.755 11.378 1.00 108.66 ? 95 TYR H CA 1 ATOM 4353 C C . TYR C 3 95 ? -26.233 -11.918 11.044 1.00 108.66 ? 95 TYR H C 1 ATOM 4354 O O . TYR C 3 95 ? -26.745 -13.025 10.907 1.00 108.66 ? 95 TYR H O 1 ATOM 4355 C CB . TYR C 3 95 ? -23.972 -11.728 10.067 1.00 71.59 ? 95 TYR H CB 1 ATOM 4356 C CG . TYR C 3 95 ? -22.541 -11.331 10.175 1.00 71.59 ? 95 TYR H CG 1 ATOM 4357 C CD1 . TYR C 3 95 ? -22.162 -10.018 10.075 1.00 71.59 ? 95 TYR H CD1 1 ATOM 4358 C CD2 . TYR C 3 95 ? -21.547 -12.288 10.186 1.00 71.59 ? 95 TYR H CD2 1 ATOM 4359 C CE1 . TYR C 3 95 ? -20.848 -9.674 9.994 1.00 71.59 ? 95 TYR H CE1 1 ATOM 4360 C CE2 . TYR C 3 95 ? -20.240 -11.951 10.096 1.00 71.59 ? 95 TYR H CE2 1 ATOM 4361 C CZ . TYR C 3 95 ? -19.895 -10.633 9.997 1.00 71.59 ? 95 TYR H CZ 1 ATOM 4362 O OH . TYR C 3 95 ? -18.593 -10.218 9.847 1.00 71.59 ? 95 TYR H OH 1 ATOM 4363 N N . CYS C 3 96 ? -26.957 -10.814 11.021 1.00 57.54 ? 96 CYS H N 1 ATOM 4364 C CA . CYS C 3 96 ? -28.360 -10.835 10.664 1.00 57.54 ? 96 CYS H CA 1 ATOM 4365 C C . CYS C 3 96 ? -28.400 -10.380 9.161 1.00 57.54 ? 96 CYS H C 1 ATOM 4366 O O . CYS C 3 96 ? -27.649 -9.449 8.782 1.00 57.54 ? 96 CYS H O 1 ATOM 4367 C CB . CYS C 3 96 ? -28.996 -9.815 11.549 1.00 64.47 ? 96 CYS H CB 1 ATOM 4368 S SG . CYS C 3 96 ? -30.367 -8.853 10.889 1.00 64.47 ? 96 CYS H SG 1 ATOM 4369 N N . ALA C 3 97 ? -29.146 -11.114 8.284 1.00 65.88 ? 97 ALA H N 1 ATOM 4370 C CA . ALA C 3 97 ? -29.273 -10.809 6.819 1.00 65.88 ? 97 ALA H CA 1 ATOM 4371 C C . ALA C 3 97 ? -30.650 -10.542 6.372 1.00 65.88 ? 97 ALA H C 1 ATOM 4372 O O . ALA C 3 97 ? -31.523 -11.272 6.751 1.00 65.88 ? 97 ALA H O 1 ATOM 4373 C CB . ALA C 3 97 ? -28.741 -11.931 5.979 1.00 49.30 ? 97 ALA H CB 1 ATOM 4374 N N . THR C 3 98 ? -30.843 -9.573 5.492 1.00 84.30 ? 98 THR H N 1 ATOM 4375 C CA . THR C 3 98 ? -32.181 -9.240 4.925 1.00 84.30 ? 98 THR H CA 1 ATOM 4376 C C . THR C 3 98 ? -32.259 -8.904 3.459 1.00 84.30 ? 98 THR H C 1 ATOM 4377 O O . THR C 3 98 ? -31.341 -8.305 2.904 1.00 84.30 ? 98 THR H O 1 ATOM 4378 C CB . THR C 3 98 ? -32.841 -8.029 5.608 1.00 26.72 ? 98 THR H CB 1 ATOM 4379 O OG1 . THR C 3 98 ? -34.098 -7.787 5.011 1.00 26.72 ? 98 THR H OG1 1 ATOM 4380 C CG2 . THR C 3 98 ? -32.014 -6.866 5.503 1.00 26.72 ? 98 THR H CG2 1 ATOM 4381 N N . GLY C 3 99 ? -33.405 -9.215 2.856 1.00 60.30 ? 99 GLY H N 1 ATOM 4382 C CA . GLY C 3 99 ? -33.523 -8.926 1.446 1.00 60.30 ? 99 GLY H CA 1 ATOM 4383 C C . GLY C 3 99 ? -34.482 -7.767 1.398 1.00 60.30 ? 99 GLY H C 1 ATOM 4384 O O . GLY C 3 99 ? -35.238 -7.551 2.354 1.00 60.30 ? 99 GLY H O 1 ATOM 4385 N N . GLY C 3 100 ? -34.447 -7.023 0.301 1.00 90.66 ? 100 GLY H N 1 ATOM 4386 C CA . GLY C 3 100 ? -35.317 -5.877 0.133 1.00 90.66 ? 100 GLY H CA 1 ATOM 4387 C C . GLY C 3 100 ? -35.142 -5.141 -1.187 1.00 90.66 ? 100 GLY H C 1 ATOM 4388 O O . GLY C 3 100 ? -34.260 -5.406 -2.009 1.00 90.66 ? 100 GLY H O 1 ATOM 4389 N N . ASN C 3 101 ? -36.059 -4.235 -1.415 1.00 52.68 ? 101 ASN H N 1 ATOM 4390 C CA . ASN C 3 101 ? -36.006 -3.451 -2.583 1.00 52.68 ? 101 ASN H CA 1 ATOM 4391 C C . ASN C 3 101 ? -35.823 -4.460 -3.730 1.00 52.68 ? 101 ASN H C 1 ATOM 4392 O O . ASN C 3 101 ? -35.126 -4.224 -4.657 1.00 52.68 ? 101 ASN H O 1 ATOM 4393 C CB . ASN C 3 101 ? -34.809 -2.572 -2.389 1.00 100.08 ? 101 ASN H CB 1 ATOM 4394 C CG . ASN C 3 101 ? -35.017 -1.521 -1.311 1.00 100.08 ? 101 ASN H CG 1 ATOM 4395 O OD1 . ASN C 3 101 ? -36.088 -1.065 -1.071 1.00 100.08 ? 101 ASN H OD1 1 ATOM 4396 N ND2 . ASN C 3 101 ? -33.974 -1.181 -0.641 1.00 100.08 ? 101 ASN H ND2 1 ATOM 4397 N N . TYR C 3 102 ? -36.497 -5.577 -3.660 1.00 78.39 ? 102 TYR H N 1 ATOM 4398 C CA . TYR C 3 102 ? -36.446 -6.647 -4.643 1.00 78.39 ? 102 TYR H CA 1 ATOM 4399 C C . TYR C 3 102 ? -37.699 -7.374 -4.757 1.00 78.39 ? 102 TYR H C 1 ATOM 4400 O O . TYR C 3 102 ? -38.364 -7.500 -3.732 1.00 78.39 ? 102 TYR H O 1 ATOM 4401 C CB . TYR C 3 102 ? -35.333 -7.618 -4.316 1.00 63.16 ? 102 TYR H CB 1 ATOM 4402 C CG . TYR C 3 102 ? -35.250 -8.793 -5.278 1.00 63.16 ? 102 TYR H CG 1 ATOM 4403 C CD1 . TYR C 3 102 ? -34.485 -8.699 -6.439 1.00 63.16 ? 102 TYR H CD1 1 ATOM 4404 C CD2 . TYR C 3 102 ? -35.607 -10.069 -4.884 1.00 63.16 ? 102 TYR H CD2 1 ATOM 4405 C CE1 . TYR C 3 102 ? -34.081 -9.790 -7.171 1.00 63.16 ? 102 TYR H CE1 1 ATOM 4406 C CE2 . TYR C 3 102 ? -35.170 -11.193 -5.616 1.00 63.16 ? 102 TYR H CE2 1 ATOM 4407 C CZ . TYR C 3 102 ? -34.396 -11.026 -6.768 1.00 63.16 ? 102 TYR H CZ 1 ATOM 4408 O OH . TYR C 3 102 ? -33.836 -12.037 -7.536 1.00 63.16 ? 102 TYR H OH 1 ATOM 4409 N N . TYR C 3 103 ? -38.053 -7.934 -5.922 1.00 64.18 ? 103 TYR H N 1 ATOM 4410 C CA . TYR C 3 103 ? -39.336 -8.624 -5.871 1.00 64.18 ? 103 TYR H CA 1 ATOM 4411 C C . TYR C 3 103 ? -39.115 -10.112 -5.606 1.00 64.18 ? 103 TYR H C 1 ATOM 4412 O O . TYR C 3 103 ? -38.773 -10.905 -6.492 1.00 64.18 ? 103 TYR H O 1 ATOM 4413 C CB . TYR C 3 103 ? -40.048 -8.337 -7.154 1.00 82.39 ? 103 TYR H CB 1 ATOM 4414 C CG . TYR C 3 103 ? -39.127 -8.614 -8.246 1.00 82.39 ? 103 TYR H CG 1 ATOM 4415 C CD1 . TYR C 3 103 ? -39.033 -9.866 -8.844 1.00 82.39 ? 103 TYR H CD1 1 ATOM 4416 C CD2 . TYR C 3 103 ? -38.271 -7.597 -8.657 1.00 82.39 ? 103 TYR H CD2 1 ATOM 4417 C CE1 . TYR C 3 103 ? -38.064 -10.100 -9.851 1.00 82.39 ? 103 TYR H CE1 1 ATOM 4418 C CE2 . TYR C 3 103 ? -37.286 -7.801 -9.665 1.00 82.39 ? 103 TYR H CE2 1 ATOM 4419 C CZ . TYR C 3 103 ? -37.165 -9.052 -10.268 1.00 82.39 ? 103 TYR H CZ 1 ATOM 4420 O OH . TYR C 3 103 ? -36.134 -9.257 -11.210 1.00 82.39 ? 103 TYR H OH 1 ATOM 4421 N N . ASN C 3 104 ? -39.623 -10.422 -4.393 1.00 72.39 ? 104 ASN H N 1 ATOM 4422 C CA . ASN C 3 104 ? -39.613 -11.643 -3.601 1.00 72.39 ? 104 ASN H CA 1 ATOM 4423 C C . ASN C 3 104 ? -40.892 -12.477 -3.363 1.00 72.39 ? 104 ASN H C 1 ATOM 4424 O O . ASN C 3 104 ? -41.110 -13.125 -2.340 1.00 72.39 ? 104 ASN H O 1 ATOM 4425 C CB . ASN C 3 104 ? -38.633 -11.551 -2.386 1.00 58.13 ? 104 ASN H CB 1 ATOM 4426 C CG . ASN C 3 104 ? -39.019 -10.576 -1.186 1.00 58.13 ? 104 ASN H CG 1 ATOM 4427 O OD1 . ASN C 3 104 ? -39.845 -9.701 -1.291 1.00 58.13 ? 104 ASN H OD1 1 ATOM 4428 N ND2 . ASN C 3 104 ? -38.314 -10.728 -0.071 1.00 58.13 ? 104 ASN H ND2 1 ATOM 4429 N N . LEU C 3 105 ? -41.809 -12.317 -4.320 1.00 146.77 ? 105 LEU H N 1 ATOM 4430 C CA . LEU C 3 105 ? -43.019 -13.127 -4.468 1.00 146.77 ? 105 LEU H CA 1 ATOM 4431 C C . LEU C 3 105 ? -42.319 -14.451 -4.642 1.00 146.77 ? 105 LEU H C 1 ATOM 4432 O O . LEU C 3 105 ? -42.789 -15.458 -4.141 1.00 146.77 ? 105 LEU H O 1 ATOM 4433 C CB . LEU C 3 105 ? -43.459 -13.082 -5.874 1.00 34.09 ? 105 LEU H CB 1 ATOM 4434 C CG . LEU C 3 105 ? -44.566 -13.656 -6.676 1.00 34.09 ? 105 LEU H CG 1 ATOM 4435 C CD1 . LEU C 3 105 ? -45.981 -13.245 -6.549 1.00 34.09 ? 105 LEU H CD1 1 ATOM 4436 C CD2 . LEU C 3 105 ? -44.029 -13.361 -8.019 1.00 34.09 ? 105 LEU H CD2 1 ATOM 4437 N N . TRP C 3 106 ? -41.204 -14.405 -5.404 1.00 94.75 ? 106 TRP H N 1 ATOM 4438 C CA . TRP C 3 106 ? -40.409 -15.551 -5.859 1.00 94.75 ? 106 TRP H CA 1 ATOM 4439 C C . TRP C 3 106 ? -40.071 -16.047 -4.471 1.00 94.75 ? 106 TRP H C 1 ATOM 4440 O O . TRP C 3 106 ? -40.262 -17.213 -4.160 1.00 94.75 ? 106 TRP H O 1 ATOM 4441 C CB . TRP C 3 106 ? -39.106 -15.031 -6.540 1.00 189.86 ? 106 TRP H CB 1 ATOM 4442 C CG . TRP C 3 106 ? -39.228 -14.522 -8.019 1.00 189.86 ? 106 TRP H CG 1 ATOM 4443 C CD1 . TRP C 3 106 ? -39.243 -13.197 -8.399 1.00 189.86 ? 106 TRP H CD1 1 ATOM 4444 C CD2 . TRP C 3 106 ? -39.526 -15.274 -9.228 1.00 189.86 ? 106 TRP H CD2 1 ATOM 4445 N NE1 . TRP C 3 106 ? -39.537 -13.080 -9.735 1.00 189.86 ? 106 TRP H NE1 1 ATOM 4446 C CE2 . TRP C 3 106 ? -39.716 -14.330 -10.269 1.00 189.86 ? 106 TRP H CE2 1 ATOM 4447 C CE3 . TRP C 3 106 ? -39.661 -16.643 -9.529 1.00 189.86 ? 106 TRP H CE3 1 ATOM 4448 C CZ2 . TRP C 3 106 ? -40.032 -14.711 -11.577 1.00 189.86 ? 106 TRP H CZ2 1 ATOM 4449 C CZ3 . TRP C 3 106 ? -39.975 -17.013 -10.832 1.00 189.86 ? 106 TRP H CZ3 1 ATOM 4450 C CH2 . TRP C 3 106 ? -40.156 -16.051 -11.833 1.00 189.86 ? 106 TRP H CH2 1 ATOM 4451 N N . THR C 3 107 ? -39.796 -15.079 -3.603 1.00 109.38 ? 107 THR H N 1 ATOM 4452 C CA . THR C 3 107 ? -39.443 -15.299 -2.183 1.00 109.38 ? 107 THR H CA 1 ATOM 4453 C C . THR C 3 107 ? -38.230 -16.295 -1.951 1.00 109.38 ? 107 THR H C 1 ATOM 4454 O O . THR C 3 107 ? -37.407 -16.146 -1.034 1.00 109.38 ? 107 THR H O 1 ATOM 4455 C CB . THR C 3 107 ? -40.734 -15.801 -1.475 1.00 119.19 ? 107 THR H CB 1 ATOM 4456 O OG1 . THR C 3 107 ? -41.876 -14.990 -1.860 1.00 119.19 ? 107 THR H OG1 1 ATOM 4457 C CG2 . THR C 3 107 ? -40.535 -15.764 0.020 1.00 119.19 ? 107 THR H CG2 1 ATOM 4458 N N . GLY C 3 108 ? -38.226 -17.322 -2.797 1.00 82.73 ? 108 GLY H N 1 ATOM 4459 C CA . GLY C 3 108 ? -37.192 -18.314 -2.958 1.00 82.73 ? 108 GLY H CA 1 ATOM 4460 C C . GLY C 3 108 ? -35.969 -17.607 -3.350 1.00 82.73 ? 108 GLY H C 1 ATOM 4461 O O . GLY C 3 108 ? -34.960 -17.921 -2.881 1.00 82.73 ? 108 GLY H O 1 ATOM 4462 N N . TYR C 3 109 ? -36.105 -16.617 -4.206 1.00 148.92 ? 109 TYR H N 1 ATOM 4463 C CA . TYR C 3 109 ? -35.007 -15.870 -4.799 1.00 148.92 ? 109 TYR H CA 1 ATOM 4464 C C . TYR C 3 109 ? -34.320 -14.587 -4.276 1.00 148.92 ? 109 TYR H C 1 ATOM 4465 O O . TYR C 3 109 ? -33.368 -14.138 -4.927 1.00 148.92 ? 109 TYR H O 1 ATOM 4466 C CB . TYR C 3 109 ? -35.263 -15.701 -6.321 1.00 199.15 ? 109 TYR H CB 1 ATOM 4467 C CG . TYR C 3 109 ? -35.378 -16.992 -7.172 1.00 199.15 ? 109 TYR H CG 1 ATOM 4468 C CD1 . TYR C 3 109 ? -34.313 -17.918 -7.253 1.00 199.15 ? 109 TYR H CD1 1 ATOM 4469 C CD2 . TYR C 3 109 ? -36.538 -17.275 -7.913 1.00 199.15 ? 109 TYR H CD2 1 ATOM 4470 C CE1 . TYR C 3 109 ? -34.407 -19.092 -8.060 1.00 199.15 ? 109 TYR H CE1 1 ATOM 4471 C CE2 . TYR C 3 109 ? -36.640 -18.446 -8.718 1.00 199.15 ? 109 TYR H CE2 1 ATOM 4472 C CZ . TYR C 3 109 ? -35.573 -19.346 -8.786 1.00 199.15 ? 109 TYR H CZ 1 ATOM 4473 O OH . TYR C 3 109 ? -35.678 -20.484 -9.570 1.00 199.15 ? 109 TYR H OH 1 ATOM 4474 N N . TYR C 3 110 ? -34.684 -13.981 -3.143 1.00 67.64 ? 110 TYR H N 1 ATOM 4475 C CA . TYR C 3 110 ? -33.973 -12.722 -2.905 1.00 67.64 ? 110 TYR H CA 1 ATOM 4476 C C . TYR C 3 110 ? -32.486 -12.825 -2.558 1.00 67.64 ? 110 TYR H C 1 ATOM 4477 O O . TYR C 3 110 ? -31.947 -13.877 -2.205 1.00 67.64 ? 110 TYR H O 1 ATOM 4478 C CB . TYR C 3 110 ? -34.631 -11.911 -1.784 1.00 66.98 ? 110 TYR H CB 1 ATOM 4479 C CG . TYR C 3 110 ? -34.678 -12.605 -0.469 1.00 66.98 ? 110 TYR H CG 1 ATOM 4480 C CD1 . TYR C 3 110 ? -34.854 -11.893 0.714 1.00 66.98 ? 110 TYR H CD1 1 ATOM 4481 C CD2 . TYR C 3 110 ? -34.654 -13.974 -0.406 1.00 66.98 ? 110 TYR H CD2 1 ATOM 4482 C CE1 . TYR C 3 110 ? -35.040 -12.555 1.960 1.00 66.98 ? 110 TYR H CE1 1 ATOM 4483 C CE2 . TYR C 3 110 ? -34.814 -14.641 0.803 1.00 66.98 ? 110 TYR H CE2 1 ATOM 4484 C CZ . TYR C 3 110 ? -35.027 -13.930 1.978 1.00 66.98 ? 110 TYR H CZ 1 ATOM 4485 O OH . TYR C 3 110 ? -35.379 -14.594 3.105 1.00 66.98 ? 110 TYR H OH 1 ATOM 4486 N N . PRO C 3 111 ? -31.780 -11.712 -2.798 1.00 101.13 ? 111 PRO H N 1 ATOM 4487 C CA . PRO C 3 111 ? -30.355 -11.628 -2.512 1.00 101.13 ? 111 PRO H CA 1 ATOM 4488 C C . PRO C 3 111 ? -30.293 -11.206 -1.041 1.00 101.13 ? 111 PRO H C 1 ATOM 4489 O O . PRO C 3 111 ? -31.325 -10.820 -0.495 1.00 101.13 ? 111 PRO H O 1 ATOM 4490 C CB . PRO C 3 111 ? -29.920 -10.502 -3.456 1.00 50.26 ? 111 PRO H CB 1 ATOM 4491 C CG . PRO C 3 111 ? -31.176 -9.545 -3.547 1.00 50.26 ? 111 PRO H CG 1 ATOM 4492 C CD . PRO C 3 111 ? -32.226 -10.606 -3.706 1.00 50.26 ? 111 PRO H CD 1 ATOM 4493 N N . LEU C 3 112 ? -29.119 -11.259 -0.398 1.00 48.89 ? 112 LEU H N 1 ATOM 4494 C CA . LEU C 3 112 ? -28.958 -10.791 1.011 1.00 48.89 ? 112 LEU H CA 1 ATOM 4495 C C . LEU C 3 112 ? -28.378 -9.398 0.826 1.00 48.89 ? 112 LEU H C 1 ATOM 4496 O O . LEU C 3 112 ? -27.200 -9.188 0.735 1.00 48.89 ? 112 LEU H O 1 ATOM 4497 C CB . LEU C 3 112 ? -27.957 -11.729 1.618 1.00 37.34 ? 112 LEU H CB 1 ATOM 4498 C CG . LEU C 3 112 ? -28.609 -13.092 1.771 1.00 37.34 ? 112 LEU H CG 1 ATOM 4499 C CD1 . LEU C 3 112 ? -27.556 -14.006 2.105 1.00 37.34 ? 112 LEU H CD1 1 ATOM 4500 C CD2 . LEU C 3 112 ? -29.432 -13.124 3.044 1.00 37.34 ? 112 LEU H CD2 1 ATOM 4501 N N . ALA C 3 113 ? -29.323 -8.504 0.624 1.00 67.23 ? 113 ALA H N 1 ATOM 4502 C CA . ALA C 3 113 ? -29.146 -7.100 0.433 1.00 67.23 ? 113 ALA H CA 1 ATOM 4503 C C . ALA C 3 113 ? -28.718 -6.222 1.519 1.00 67.23 ? 113 ALA H C 1 ATOM 4504 O O . ALA C 3 113 ? -28.128 -5.268 1.224 1.00 67.23 ? 113 ALA H O 1 ATOM 4505 C CB . ALA C 3 113 ? -30.407 -6.508 -0.242 1.00 147.69 ? 113 ALA H CB 1 ATOM 4506 N N . TYR C 3 114 ? -29.186 -6.386 2.742 1.00 71.08 ? 114 TYR H N 1 ATOM 4507 C CA . TYR C 3 114 ? -28.618 -5.525 3.739 1.00 71.08 ? 114 TYR H CA 1 ATOM 4508 C C . TYR C 3 114 ? -28.041 -6.448 4.790 1.00 71.08 ? 114 TYR H C 1 ATOM 4509 O O . TYR C 3 114 ? -28.755 -7.366 5.237 1.00 71.08 ? 114 TYR H O 1 ATOM 4510 C CB . TYR C 3 114 ? -29.704 -4.580 4.244 1.00 67.68 ? 114 TYR H CB 1 ATOM 4511 C CG . TYR C 3 114 ? -30.152 -3.647 3.146 1.00 67.68 ? 114 TYR H CG 1 ATOM 4512 C CD1 . TYR C 3 114 ? -29.289 -2.771 2.552 1.00 67.68 ? 114 TYR H CD1 1 ATOM 4513 C CD2 . TYR C 3 114 ? -31.361 -3.781 2.583 1.00 67.68 ? 114 TYR H CD2 1 ATOM 4514 C CE1 . TYR C 3 114 ? -29.621 -2.102 1.436 1.00 67.68 ? 114 TYR H CE1 1 ATOM 4515 C CE2 . TYR C 3 114 ? -31.679 -3.129 1.484 1.00 67.68 ? 114 TYR H CE2 1 ATOM 4516 C CZ . TYR C 3 114 ? -30.812 -2.306 0.907 1.00 67.68 ? 114 TYR H CZ 1 ATOM 4517 O OH . TYR C 3 114 ? -31.113 -1.750 -0.287 1.00 67.68 ? 114 TYR H OH 1 ATOM 4518 N N . TRP C 3 115 ? -26.871 -6.107 5.311 1.00 59.24 ? 115 TRP H N 1 ATOM 4519 C CA . TRP C 3 115 ? -26.150 -6.846 6.329 1.00 59.24 ? 115 TRP H CA 1 ATOM 4520 C C . TRP C 3 115 ? -25.912 -6.075 7.563 1.00 59.24 ? 115 TRP H C 1 ATOM 4521 O O . TRP C 3 115 ? -25.710 -4.880 7.502 1.00 59.24 ? 115 TRP H O 1 ATOM 4522 C CB . TRP C 3 115 ? -24.851 -7.457 5.821 1.00 62.07 ? 115 TRP H CB 1 ATOM 4523 C CG . TRP C 3 115 ? -24.975 -8.551 4.982 1.00 62.07 ? 115 TRP H CG 1 ATOM 4524 C CD1 . TRP C 3 115 ? -25.664 -8.638 3.887 1.00 62.07 ? 115 TRP H CD1 1 ATOM 4525 C CD2 . TRP C 3 115 ? -24.486 -9.877 5.275 1.00 62.07 ? 115 TRP H CD2 1 ATOM 4526 N NE1 . TRP C 3 115 ? -25.708 -9.953 3.454 1.00 62.07 ? 115 TRP H NE1 1 ATOM 4527 C CE2 . TRP C 3 115 ? -24.981 -10.728 4.316 1.00 62.07 ? 115 TRP H CE2 1 ATOM 4528 C CE3 . TRP C 3 115 ? -23.675 -10.424 6.279 1.00 62.07 ? 115 TRP H CE3 1 ATOM 4529 C CZ2 . TRP C 3 115 ? -24.710 -12.125 4.334 1.00 62.07 ? 115 TRP H CZ2 1 ATOM 4530 C CZ3 . TRP C 3 115 ? -23.409 -11.821 6.293 1.00 62.07 ? 115 TRP H CZ3 1 ATOM 4531 C CH2 . TRP C 3 115 ? -23.928 -12.637 5.341 1.00 62.07 ? 115 TRP H CH2 1 ATOM 4532 N N . GLY C 3 116 ? -26.048 -6.734 8.707 1.00 103.45 ? 116 GLY H N 1 ATOM 4533 C CA . GLY C 3 116 ? -25.832 -6.049 9.960 1.00 103.45 ? 116 GLY H CA 1 ATOM 4534 C C . GLY C 3 116 ? -24.361 -5.939 10.259 1.00 103.45 ? 116 GLY H C 1 ATOM 4535 O O . GLY C 3 116 ? -23.518 -6.551 9.651 1.00 103.45 ? 116 GLY H O 1 ATOM 4536 N N . GLN C 3 117 ? -24.079 -5.176 11.279 1.00 86.59 ? 117 GLN H N 1 ATOM 4537 C CA . GLN C 3 117 ? -22.730 -4.882 11.715 1.00 86.59 ? 117 GLN H CA 1 ATOM 4538 C C . GLN C 3 117 ? -22.007 -6.136 12.090 1.00 86.59 ? 117 GLN H C 1 ATOM 4539 O O . GLN C 3 117 ? -20.814 -6.255 11.934 1.00 86.59 ? 117 GLN H O 1 ATOM 4540 C CB . GLN C 3 117 ? -22.814 -3.937 12.907 1.00 94.78 ? 117 GLN H CB 1 ATOM 4541 C CG . GLN C 3 117 ? -23.463 -4.551 14.169 1.00 94.78 ? 117 GLN H CG 1 ATOM 4542 C CD . GLN C 3 117 ? -23.548 -3.535 15.306 1.00 94.78 ? 117 GLN H CD 1 ATOM 4543 O OE1 . GLN C 3 117 ? -23.824 -2.352 15.053 1.00 94.78 ? 117 GLN H OE1 1 ATOM 4544 N NE2 . GLN C 3 117 ? -23.325 -3.985 16.561 1.00 94.78 ? 117 GLN H NE2 1 ATOM 4545 N N . GLY C 3 118 ? -22.763 -7.071 12.607 1.00 71.76 ? 118 GLY H N 1 ATOM 4546 C CA . GLY C 3 118 ? -22.228 -8.329 13.057 1.00 71.76 ? 118 GLY H CA 1 ATOM 4547 C C . GLY C 3 118 ? -22.325 -8.187 14.549 1.00 71.76 ? 118 GLY H C 1 ATOM 4548 O O . GLY C 3 118 ? -22.308 -7.093 15.057 1.00 71.76 ? 118 GLY H O 1 ATOM 4549 N N . THR C 3 119 ? -22.455 -9.297 15.250 1.00 79.80 ? 119 THR H N 1 ATOM 4550 C CA . THR C 3 119 ? -22.572 -9.292 16.682 1.00 79.80 ? 119 THR H CA 1 ATOM 4551 C C . THR C 3 119 ? -21.756 -10.442 17.070 1.00 79.80 ? 119 THR H C 1 ATOM 4552 O O . THR C 3 119 ? -21.742 -11.417 16.363 1.00 79.80 ? 119 THR H O 1 ATOM 4553 C CB . THR C 3 119 ? -23.948 -9.570 17.132 1.00 86.14 ? 119 THR H CB 1 ATOM 4554 O OG1 . THR C 3 119 ? -23.974 -9.366 18.528 1.00 86.14 ? 119 THR H OG1 1 ATOM 4555 C CG2 . THR C 3 119 ? -24.359 -10.999 16.845 1.00 86.14 ? 119 THR H CG2 1 ATOM 4556 N N . LEU C 3 120 ? -21.156 -10.403 18.240 1.00 60.43 ? 120 LEU H N 1 ATOM 4557 C CA . LEU C 3 120 ? -20.236 -11.479 18.606 1.00 60.43 ? 120 LEU H CA 1 ATOM 4558 C C . LEU C 3 120 ? -20.691 -12.306 19.773 1.00 60.43 ? 120 LEU H C 1 ATOM 4559 O O . LEU C 3 120 ? -21.452 -11.832 20.600 1.00 60.43 ? 120 LEU H O 1 ATOM 4560 C CB . LEU C 3 120 ? -18.848 -10.938 18.946 1.00 50.32 ? 120 LEU H CB 1 ATOM 4561 C CG . LEU C 3 120 ? -17.697 -11.902 19.367 1.00 50.32 ? 120 LEU H CG 1 ATOM 4562 C CD1 . LEU C 3 120 ? -17.439 -12.893 18.197 1.00 50.32 ? 120 LEU H CD1 1 ATOM 4563 C CD2 . LEU C 3 120 ? -16.375 -11.148 19.659 1.00 50.32 ? 120 LEU H CD2 1 ATOM 4564 N N . VAL C 3 121 ? -20.478 -13.607 19.674 1.00 88.10 ? 121 VAL H N 1 ATOM 4565 C CA . VAL C 3 121 ? -20.744 -14.498 20.779 1.00 88.10 ? 121 VAL H CA 1 ATOM 4566 C C . VAL C 3 121 ? -19.522 -15.344 20.969 1.00 88.10 ? 121 VAL H C 1 ATOM 4567 O O . VAL C 3 121 ? -19.034 -15.907 19.998 1.00 88.10 ? 121 VAL H O 1 ATOM 4568 C CB . VAL C 3 121 ? -22.027 -15.391 20.553 1.00 40.16 ? 121 VAL H CB 1 ATOM 4569 C CG1 . VAL C 3 121 ? -22.267 -16.279 21.691 1.00 40.16 ? 121 VAL H CG1 1 ATOM 4570 C CG2 . VAL C 3 121 ? -23.220 -14.537 20.513 1.00 40.16 ? 121 VAL H CG2 1 ATOM 4571 N N . THR C 3 122 ? -19.003 -15.452 22.191 1.00 65.65 ? 122 THR H N 1 ATOM 4572 C CA . THR C 3 122 ? -17.862 -16.396 22.402 1.00 65.65 ? 122 THR H CA 1 ATOM 4573 C C . THR C 3 122 ? -18.305 -17.261 23.574 1.00 65.65 ? 122 THR H C 1 ATOM 4574 O O . THR C 3 122 ? -18.784 -16.754 24.584 1.00 65.65 ? 122 THR H O 1 ATOM 4575 C CB . THR C 3 122 ? -16.502 -15.738 22.752 1.00 62.06 ? 122 THR H CB 1 ATOM 4576 O OG1 . THR C 3 122 ? -16.687 -14.965 23.927 1.00 62.06 ? 122 THR H OG1 1 ATOM 4577 C CG2 . THR C 3 122 ? -15.935 -14.891 21.663 1.00 62.06 ? 122 THR H CG2 1 ATOM 4578 N N . VAL C 3 123 ? -17.995 -18.548 23.462 1.00 123.66 ? 123 VAL H N 1 ATOM 4579 C CA . VAL C 3 123 ? -18.472 -19.532 24.410 1.00 123.66 ? 123 VAL H CA 1 ATOM 4580 C C . VAL C 3 123 ? -17.221 -20.094 24.980 1.00 123.66 ? 123 VAL H C 1 ATOM 4581 O O . VAL C 3 123 ? -16.348 -20.522 24.253 1.00 123.66 ? 123 VAL H O 1 ATOM 4582 C CB . VAL C 3 123 ? -19.174 -20.688 23.665 1.00 105.81 ? 123 VAL H CB 1 ATOM 4583 C CG1 . VAL C 3 123 ? -19.680 -21.729 24.643 1.00 105.81 ? 123 VAL H CG1 1 ATOM 4584 C CG2 . VAL C 3 123 ? -20.291 -20.152 22.796 1.00 105.81 ? 123 VAL H CG2 1 ATOM 4585 N N . SER C 3 124 ? -17.169 -20.136 26.301 1.00 110.77 ? 124 SER H N 1 ATOM 4586 C CA . SER C 3 124 ? -15.991 -20.601 27.010 1.00 110.77 ? 124 SER H CA 1 ATOM 4587 C C . SER C 3 124 ? -16.224 -21.103 28.447 1.00 110.77 ? 124 SER H C 1 ATOM 4588 O O . SER C 3 124 ? -17.219 -20.783 29.114 1.00 110.77 ? 124 SER H O 1 ATOM 4589 C CB . SER C 3 124 ? -14.922 -19.497 26.984 1.00 56.27 ? 124 SER H CB 1 ATOM 4590 O OG . SER C 3 124 ? -13.783 -19.906 27.653 1.00 56.27 ? 124 SER H OG 1 ATOM 4591 N N . SER C 3 125 ? -15.353 -22.027 28.811 1.00 79.12 ? 125 SER H N 1 ATOM 4592 C CA . SER C 3 125 ? -15.212 -22.637 30.112 1.00 79.12 ? 125 SER H CA 1 ATOM 4593 C C . SER C 3 125 ? -14.893 -21.602 31.208 1.00 79.12 ? 125 SER H C 1 ATOM 4594 O O . SER C 3 125 ? -15.343 -21.670 32.331 1.00 79.12 ? 125 SER H O 1 ATOM 4595 C CB . SER C 3 125 ? -14.141 -23.703 30.008 1.00 111.78 ? 125 SER H CB 1 ATOM 4596 O OG . SER C 3 125 ? -14.526 -24.686 29.051 1.00 111.78 ? 125 SER H OG 1 ATOM 4597 N N . ALA C 3 126 ? -14.050 -20.660 30.851 1.00 103.13 ? 126 ALA H N 1 ATOM 4598 C CA . ALA C 3 126 ? -13.540 -19.635 31.742 1.00 103.13 ? 126 ALA H CA 1 ATOM 4599 C C . ALA C 3 126 ? -14.524 -18.583 32.189 1.00 103.13 ? 126 ALA H C 1 ATOM 4600 O O . ALA C 3 126 ? -15.517 -18.318 31.525 1.00 103.13 ? 126 ALA H O 1 ATOM 4601 C CB . ALA C 3 126 ? -12.334 -18.956 31.091 1.00 83.63 ? 126 ALA H CB 1 ATOM 4602 N N . SER C 3 127 ? -14.176 -17.949 33.307 1.00 88.19 ? 127 SER H N 1 ATOM 4603 C CA . SER C 3 127 ? -14.960 -16.895 33.975 1.00 88.19 ? 127 SER H CA 1 ATOM 4604 C C . SER C 3 127 ? -13.833 -15.848 34.136 1.00 88.19 ? 127 SER H C 1 ATOM 4605 O O . SER C 3 127 ? -12.658 -16.202 33.989 1.00 88.19 ? 127 SER H O 1 ATOM 4606 C CB . SER C 3 127 ? -15.528 -17.379 35.328 1.00 121.31 ? 127 SER H CB 1 ATOM 4607 O OG . SER C 3 127 ? -14.507 -17.624 36.286 1.00 121.31 ? 127 SER H OG 1 ATOM 4608 N N . THR C 3 128 ? -14.123 -14.615 34.528 1.00 88.98 ? 128 THR H N 1 ATOM 4609 C CA . THR C 3 128 ? -13.062 -13.639 34.393 1.00 88.98 ? 128 THR H CA 1 ATOM 4610 C C . THR C 3 128 ? -11.814 -13.909 35.141 1.00 88.98 ? 128 THR H C 1 ATOM 4611 O O . THR C 3 128 ? -11.850 -14.147 36.297 1.00 88.98 ? 128 THR H O 1 ATOM 4612 C CB . THR C 3 128 ? -13.551 -12.323 34.940 1.00 55.94 ? 128 THR H CB 1 ATOM 4613 O OG1 . THR C 3 128 ? -14.703 -11.890 34.210 1.00 55.94 ? 128 THR H OG1 1 ATOM 4614 C CG2 . THR C 3 128 ? -12.446 -11.313 34.973 1.00 55.94 ? 128 THR H CG2 1 ATOM 4615 N N . LYS C 3 129 ? -10.686 -13.824 34.447 1.00 109.17 ? 129 LYS H N 1 ATOM 4616 C CA . LYS C 3 129 ? -9.363 -14.056 35.044 1.00 109.17 ? 129 LYS H CA 1 ATOM 4617 C C . LYS C 3 129 ? -8.392 -12.975 34.666 1.00 109.17 ? 129 LYS H C 1 ATOM 4618 O O . LYS C 3 129 ? -8.315 -12.592 33.527 1.00 109.17 ? 129 LYS H O 1 ATOM 4619 C CB . LYS C 3 129 ? -8.732 -15.381 34.608 1.00 74.58 ? 129 LYS H CB 1 ATOM 4620 C CG . LYS C 3 129 ? -7.451 -15.634 35.296 1.00 74.58 ? 129 LYS H CG 1 ATOM 4621 C CD . LYS C 3 129 ? -6.841 -16.903 34.889 1.00 74.58 ? 129 LYS H CD 1 ATOM 4622 C CE . LYS C 3 129 ? -5.619 -17.207 35.796 1.00 74.58 ? 129 LYS H CE 1 ATOM 4623 N NZ . LYS C 3 129 ? -4.431 -16.288 35.817 1.00 74.58 ? 129 LYS H NZ 1 ATOM 4624 N N . GLY C 3 130 ? -7.638 -12.471 35.609 1.00 119.82 ? 130 GLY H N 1 ATOM 4625 C CA . GLY C 3 130 ? -6.658 -11.454 35.276 1.00 119.82 ? 130 GLY H CA 1 ATOM 4626 C C . GLY C 3 130 ? -5.487 -11.988 34.463 1.00 119.82 ? 130 GLY H C 1 ATOM 4627 O O . GLY C 3 130 ? -5.288 -13.206 34.432 1.00 119.82 ? 130 GLY H O 1 ATOM 4628 N N . PRO C 3 131 ? -4.737 -11.120 33.750 1.00 91.54 ? 131 PRO H N 1 ATOM 4629 C CA . PRO C 3 131 ? -3.590 -11.526 32.952 1.00 91.54 ? 131 PRO H CA 1 ATOM 4630 C C . PRO C 3 131 ? -2.441 -11.704 33.908 1.00 91.54 ? 131 PRO H C 1 ATOM 4631 O O . PRO C 3 131 ? -2.522 -11.175 34.980 1.00 91.54 ? 131 PRO H O 1 ATOM 4632 C CB . PRO C 3 131 ? -3.391 -10.327 32.048 1.00 44.20 ? 131 PRO H CB 1 ATOM 4633 C CG . PRO C 3 131 ? -3.862 -9.223 32.847 1.00 44.20 ? 131 PRO H CG 1 ATOM 4634 C CD . PRO C 3 131 ? -5.083 -9.733 33.416 1.00 44.20 ? 131 PRO H CD 1 ATOM 4635 N N . SER C 3 132 ? -1.375 -12.401 33.529 1.00 59.17 ? 132 SER H N 1 ATOM 4636 C CA . SER C 3 132 ? -0.193 -12.605 34.387 1.00 59.17 ? 132 SER H CA 1 ATOM 4637 C C . SER C 3 132 ? 0.806 -12.106 33.414 1.00 59.17 ? 132 SER H C 1 ATOM 4638 O O . SER C 3 132 ? 0.587 -12.319 32.206 1.00 59.17 ? 132 SER H O 1 ATOM 4639 C CB . SER C 3 132 ? 0.108 -14.072 34.644 1.00 87.25 ? 132 SER H CB 1 ATOM 4640 O OG . SER C 3 132 ? -0.950 -14.736 35.291 1.00 87.25 ? 132 SER H OG 1 ATOM 4641 N N . VAL C 3 133 ? 1.846 -11.393 33.859 1.00 95.98 ? 133 VAL H N 1 ATOM 4642 C CA . VAL C 3 133 ? 2.807 -10.830 32.892 1.00 95.98 ? 133 VAL H CA 1 ATOM 4643 C C . VAL C 3 133 ? 4.269 -11.323 33.081 1.00 95.98 ? 133 VAL H C 1 ATOM 4644 O O . VAL C 3 133 ? 4.801 -11.215 34.161 1.00 95.98 ? 133 VAL H O 1 ATOM 4645 C CB . VAL C 3 133 ? 2.857 -9.303 33.019 1.00 37.79 ? 133 VAL H CB 1 ATOM 4646 C CG1 . VAL C 3 133 ? 3.900 -8.720 31.966 1.00 37.79 ? 133 VAL H CG1 1 ATOM 4647 C CG2 . VAL C 3 133 ? 1.406 -8.693 33.124 1.00 37.79 ? 133 VAL H CG2 1 ATOM 4648 N N . PHE C 3 134 ? 4.941 -11.788 32.037 1.00 48.32 ? 134 PHE H N 1 ATOM 4649 C CA . PHE C 3 134 ? 6.315 -12.250 32.164 1.00 48.32 ? 134 PHE H CA 1 ATOM 4650 C C . PHE C 3 134 ? 7.017 -11.382 31.100 1.00 48.32 ? 134 PHE H C 1 ATOM 4651 O O . PHE C 3 134 ? 6.375 -11.005 30.142 1.00 48.32 ? 134 PHE H O 1 ATOM 4652 C CB . PHE C 3 134 ? 6.423 -13.756 31.798 1.00 118.67 ? 134 PHE H CB 1 ATOM 4653 C CG . PHE C 3 134 ? 5.578 -14.694 32.665 1.00 118.67 ? 134 PHE H CG 1 ATOM 4654 C CD1 . PHE C 3 134 ? 5.428 -14.499 34.011 1.00 118.67 ? 134 PHE H CD1 1 ATOM 4655 C CD2 . PHE C 3 134 ? 4.908 -15.762 32.085 1.00 118.67 ? 134 PHE H CD2 1 ATOM 4656 C CE1 . PHE C 3 134 ? 4.630 -15.339 34.751 1.00 118.67 ? 134 PHE H CE1 1 ATOM 4657 C CE2 . PHE C 3 134 ? 4.108 -16.602 32.826 1.00 118.67 ? 134 PHE H CE2 1 ATOM 4658 C CZ . PHE C 3 134 ? 3.970 -16.386 34.155 1.00 118.67 ? 134 PHE H CZ 1 ATOM 4659 N N . PRO C 3 135 ? 8.340 -11.118 31.215 1.00 89.45 ? 135 PRO H N 1 ATOM 4660 C CA . PRO C 3 135 ? 9.046 -10.283 30.234 1.00 89.45 ? 135 PRO H CA 1 ATOM 4661 C C . PRO C 3 135 ? 9.906 -11.037 29.237 1.00 89.45 ? 135 PRO H C 1 ATOM 4662 O O . PRO C 3 135 ? 10.454 -12.089 29.578 1.00 89.45 ? 135 PRO H O 1 ATOM 4663 C CB . PRO C 3 135 ? 9.907 -9.434 31.118 1.00 105.96 ? 135 PRO H CB 1 ATOM 4664 C CG . PRO C 3 135 ? 10.421 -10.489 32.080 1.00 105.96 ? 135 PRO H CG 1 ATOM 4665 C CD . PRO C 3 135 ? 9.216 -11.386 32.365 1.00 105.96 ? 135 PRO H CD 1 ATOM 4666 N N . LEU C 3 136 ? 10.050 -10.525 28.008 1.00 77.13 ? 136 LEU H N 1 ATOM 4667 C CA . LEU C 3 136 ? 10.921 -11.242 27.072 1.00 77.13 ? 136 LEU H CA 1 ATOM 4668 C C . LEU C 3 136 ? 12.163 -10.395 27.198 1.00 77.13 ? 136 LEU H C 1 ATOM 4669 O O . LEU C 3 136 ? 12.145 -9.225 26.860 1.00 77.13 ? 136 LEU H O 1 ATOM 4670 C CB . LEU C 3 136 ? 10.305 -11.124 25.674 1.00 61.69 ? 136 LEU H CB 1 ATOM 4671 C CG . LEU C 3 136 ? 8.913 -11.788 25.792 1.00 61.69 ? 136 LEU H CG 1 ATOM 4672 C CD1 . LEU C 3 136 ? 8.085 -11.588 24.591 1.00 61.69 ? 136 LEU H CD1 1 ATOM 4673 C CD2 . LEU C 3 136 ? 9.084 -13.271 26.048 1.00 61.69 ? 136 LEU H CD2 1 ATOM 4674 N N . ALA C 3 137 ? 13.257 -11.002 27.624 1.00 113.31 ? 137 ALA H N 1 ATOM 4675 C CA . ALA C 3 137 ? 14.494 -10.266 27.787 1.00 113.31 ? 137 ALA H CA 1 ATOM 4676 C C . ALA C 3 137 ? 15.186 -9.990 26.462 1.00 113.31 ? 137 ALA H C 1 ATOM 4677 O O . ALA C 3 137 ? 15.379 -10.923 25.691 1.00 113.31 ? 137 ALA H O 1 ATOM 4678 C CB . ALA C 3 137 ? 15.414 -11.029 28.727 1.00 90.22 ? 137 ALA H CB 1 ATOM 4679 N N . PRO C 3 138 ? 15.593 -8.731 26.173 1.00 147.39 ? 138 PRO H N 1 ATOM 4680 C CA . PRO C 3 138 ? 16.242 -8.689 24.872 1.00 147.39 ? 138 PRO H CA 1 ATOM 4681 C C . PRO C 3 138 ? 17.345 -9.732 24.823 1.00 147.39 ? 138 PRO H C 1 ATOM 4682 O O . PRO C 3 138 ? 18.183 -9.836 25.715 1.00 147.39 ? 138 PRO H O 1 ATOM 4683 C CB . PRO C 3 138 ? 16.765 -7.251 24.777 1.00 55.62 ? 138 PRO H CB 1 ATOM 4684 C CG . PRO C 3 138 ? 16.726 -6.726 26.152 1.00 55.62 ? 138 PRO H CG 1 ATOM 4685 C CD . PRO C 3 138 ? 15.502 -7.368 26.730 1.00 55.62 ? 138 PRO H CD 1 ATOM 4686 N N . SER C 3 139 ? 17.229 -10.571 23.807 1.00 171.39 ? 139 SER H N 1 ATOM 4687 C CA . SER C 3 139 ? 18.128 -11.669 23.457 1.00 171.39 ? 139 SER H CA 1 ATOM 4688 C C . SER C 3 139 ? 19.446 -11.375 22.694 1.00 171.39 ? 139 SER H C 1 ATOM 4689 O O . SER C 3 139 ? 19.726 -10.235 22.314 1.00 171.39 ? 139 SER H O 1 ATOM 4690 C CB . SER C 3 139 ? 17.308 -12.750 22.732 1.00 104.87 ? 139 SER H CB 1 ATOM 4691 O OG . SER C 3 139 ? 16.724 -12.251 21.544 1.00 104.87 ? 139 SER H OG 1 ATOM 4692 N N . SER C 3 140 ? 20.296 -12.402 22.602 1.00 223.96 ? 140 SER H N 1 ATOM 4693 C CA . SER C 3 140 ? 21.552 -12.416 21.812 1.00 223.96 ? 140 SER H CA 1 ATOM 4694 C C . SER C 3 140 ? 21.076 -12.163 20.369 1.00 223.96 ? 140 SER H C 1 ATOM 4695 O O . SER C 3 140 ? 21.733 -11.466 19.590 1.00 223.96 ? 140 SER H O 1 ATOM 4696 C CB . SER C 3 140 ? 22.315 -13.744 21.888 1.00 107.45 ? 140 SER H CB 1 ATOM 4697 O OG . SER C 3 140 ? 23.578 -13.611 21.230 1.00 107.45 ? 140 SER H OG 1 ATOM 4698 N N . LYS C 3 141 ? 19.940 -12.807 20.058 1.00 254.74 ? 141 LYS H N 1 ATOM 4699 C CA . LYS C 3 141 ? 19.167 -12.824 18.792 1.00 254.74 ? 141 LYS H CA 1 ATOM 4700 C C . LYS C 3 141 ? 18.677 -11.424 18.377 1.00 254.74 ? 141 LYS H C 1 ATOM 4701 O O . LYS C 3 141 ? 18.600 -11.128 17.180 1.00 254.74 ? 141 LYS H O 1 ATOM 4702 C CB . LYS C 3 141 ? 17.949 -13.776 18.809 1.00 106.70 ? 141 LYS H CB 1 ATOM 4703 C CG . LYS C 3 141 ? 18.244 -15.275 18.817 1.00 106.70 ? 141 LYS H CG 1 ATOM 4704 C CD . LYS C 3 141 ? 18.286 -15.876 20.225 1.00 106.70 ? 141 LYS H CD 1 ATOM 4705 C CE . LYS C 3 141 ? 18.337 -17.396 20.163 1.00 106.70 ? 141 LYS H CE 1 ATOM 4706 N NZ . LYS C 3 141 ? 18.458 -17.985 21.522 1.00 106.70 ? 141 LYS H NZ 1 ATOM 4707 N N . SER C 3 142 ? 18.238 -10.621 19.343 1.00 133.09 ? 142 SER H N 1 ATOM 4708 C CA . SER C 3 142 ? 17.650 -9.298 19.119 1.00 133.09 ? 142 SER H CA 1 ATOM 4709 C C . SER C 3 142 ? 18.469 -8.172 18.415 1.00 133.09 ? 142 SER H C 1 ATOM 4710 O O . SER C 3 142 ? 17.852 -7.465 17.621 1.00 133.09 ? 142 SER H O 1 ATOM 4711 C CB . SER C 3 142 ? 17.206 -8.723 20.473 1.00 90.60 ? 142 SER H CB 1 ATOM 4712 O OG . SER C 3 142 ? 16.165 -9.471 21.084 1.00 90.60 ? 142 SER H OG 1 ATOM 4713 N N . THR C 3 143 ? 19.774 -7.944 18.637 1.00 211.15 ? 143 THR H N 1 ATOM 4714 C CA . THR C 3 143 ? 20.396 -6.790 17.926 1.00 211.15 ? 143 THR H CA 1 ATOM 4715 C C . THR C 3 143 ? 21.269 -6.863 16.626 1.00 211.15 ? 143 THR H C 1 ATOM 4716 O O . THR C 3 143 ? 22.397 -7.361 16.626 1.00 211.15 ? 143 THR H O 1 ATOM 4717 C CB . THR C 3 143 ? 21.275 -5.966 18.964 1.00 148.91 ? 143 THR H CB 1 ATOM 4718 O OG1 . THR C 3 143 ? 22.374 -5.330 18.286 1.00 148.91 ? 143 THR H OG1 1 ATOM 4719 C CG2 . THR C 3 143 ? 21.838 -6.876 20.064 1.00 148.91 ? 143 THR H CG2 1 ATOM 4720 N N . SER C 3 144 ? 20.725 -6.279 15.544 1.00 158.03 ? 144 SER H N 1 ATOM 4721 C CA . SER C 3 144 ? 21.399 -6.101 14.237 1.00 158.03 ? 144 SER H CA 1 ATOM 4722 C C . SER C 3 144 ? 21.173 -4.610 13.928 1.00 158.03 ? 144 SER H C 1 ATOM 4723 O O . SER C 3 144 ? 20.055 -4.101 14.111 1.00 158.03 ? 144 SER H O 1 ATOM 4724 C CB . SER C 3 144 ? 20.718 -6.904 13.099 1.00 122.18 ? 144 SER H CB 1 ATOM 4725 O OG . SER C 3 144 ? 20.774 -8.317 13.234 1.00 122.18 ? 144 SER H OG 1 ATOM 4726 N N . GLY C 3 145 ? 22.181 -3.900 13.443 1.00 135.51 ? 145 GLY H N 1 ATOM 4727 C CA . GLY C 3 145 ? 21.930 -2.509 13.119 1.00 135.51 ? 145 GLY H CA 1 ATOM 4728 C C . GLY C 3 145 ? 21.966 -1.708 14.419 1.00 135.51 ? 145 GLY H C 1 ATOM 4729 O O . GLY C 3 145 ? 21.566 -0.532 14.441 1.00 135.51 ? 145 GLY H O 1 ATOM 4730 N N . GLY C 3 146 ? 22.406 -2.339 15.517 1.00 128.61 ? 146 GLY H N 1 ATOM 4731 C CA . GLY C 3 146 ? 22.417 -1.624 16.785 1.00 128.61 ? 146 GLY H CA 1 ATOM 4732 C C . GLY C 3 146 ? 21.008 -1.618 17.395 1.00 128.61 ? 146 GLY H C 1 ATOM 4733 O O . GLY C 3 146 ? 20.732 -0.878 18.329 1.00 128.61 ? 146 GLY H O 1 ATOM 4734 N N . THR C 3 147 ? 20.107 -2.435 16.858 1.00 112.91 ? 147 THR H N 1 ATOM 4735 C CA . THR C 3 147 ? 18.724 -2.472 17.310 1.00 112.91 ? 147 THR H CA 1 ATOM 4736 C C . THR C 3 147 ? 18.279 -3.896 17.671 1.00 112.91 ? 147 THR H C 1 ATOM 4737 O O . THR C 3 147 ? 18.477 -4.841 16.898 1.00 112.91 ? 147 THR H O 1 ATOM 4738 C CB . THR C 3 147 ? 17.836 -1.984 16.153 1.00 82.72 ? 147 THR H CB 1 ATOM 4739 O OG1 . THR C 3 147 ? 18.020 -2.847 15.013 1.00 82.72 ? 147 THR H OG1 1 ATOM 4740 C CG2 . THR C 3 147 ? 18.166 -0.547 15.784 1.00 82.72 ? 147 THR H CG2 1 ATOM 4741 N N . ALA C 3 148 ? 17.511 -3.981 18.761 1.00 88.62 ? 148 ALA H N 1 ATOM 4742 C CA . ALA C 3 148 ? 17.061 -5.232 19.363 1.00 88.62 ? 148 ALA H CA 1 ATOM 4743 C C . ALA C 3 148 ? 15.588 -5.233 19.793 1.00 88.62 ? 148 ALA H C 1 ATOM 4744 O O . ALA C 3 148 ? 14.989 -4.166 19.886 1.00 88.62 ? 148 ALA H O 1 ATOM 4745 C CB . ALA C 3 148 ? 17.961 -5.550 20.534 1.00 71.21 ? 148 ALA H CB 1 ATOM 4746 N N . ALA C 3 149 ? 14.990 -6.422 19.968 1.00 79.32 ? 149 ALA H N 1 ATOM 4747 C CA . ALA C 3 149 ? 13.595 -6.558 20.423 1.00 79.32 ? 149 ALA H CA 1 ATOM 4748 C C . ALA C 3 149 ? 13.420 -7.148 21.842 1.00 79.32 ? 149 ALA H C 1 ATOM 4749 O O . ALA C 3 149 ? 14.063 -8.148 22.197 1.00 79.32 ? 149 ALA H O 1 ATOM 4750 C CB . ALA C 3 149 ? 12.863 -7.410 19.460 1.00 85.65 ? 149 ALA H CB 1 ATOM 4751 N N . LEU C 3 150 ? 12.474 -6.593 22.605 1.00 77.33 ? 150 LEU H N 1 ATOM 4752 C CA . LEU C 3 150 ? 12.232 -7.021 23.988 1.00 77.33 ? 150 LEU H CA 1 ATOM 4753 C C . LEU C 3 150 ? 10.789 -6.750 24.126 1.00 77.33 ? 150 LEU H C 1 ATOM 4754 O O . LEU C 3 150 ? 10.308 -5.865 23.455 1.00 77.33 ? 150 LEU H O 1 ATOM 4755 C CB . LEU C 3 150 ? 12.950 -6.099 24.973 1.00 66.28 ? 150 LEU H CB 1 ATOM 4756 C CG . LEU C 3 150 ? 12.593 -4.604 24.985 1.00 66.28 ? 150 LEU H CG 1 ATOM 4757 C CD1 . LEU C 3 150 ? 13.693 -3.885 25.787 1.00 66.28 ? 150 LEU H CD1 1 ATOM 4758 C CD2 . LEU C 3 150 ? 12.493 -4.019 23.639 1.00 66.28 ? 150 LEU H CD2 1 ATOM 4759 N N . GLY C 3 151 ? 10.131 -7.420 25.073 1.00 60.19 ? 151 GLY H N 1 ATOM 4760 C CA . GLY C 3 151 ? 8.679 -7.286 25.245 1.00 60.19 ? 151 GLY H CA 1 ATOM 4761 C C . GLY C 3 151 ? 7.994 -8.009 26.388 1.00 60.19 ? 151 GLY H C 1 ATOM 4762 O O . GLY C 3 151 ? 8.630 -8.557 27.263 1.00 60.19 ? 151 GLY H O 1 ATOM 4763 N N . CYS C 3 152 ? 6.677 -8.020 26.373 1.00 84.82 ? 152 CYS H N 1 ATOM 4764 C CA . CYS C 3 152 ? 5.938 -8.624 27.456 1.00 84.82 ? 152 CYS H CA 1 ATOM 4765 C C . CYS C 3 152 ? 5.183 -9.832 26.944 1.00 84.82 ? 152 CYS H C 1 ATOM 4766 O O . CYS C 3 152 ? 4.831 -9.872 25.808 1.00 84.82 ? 152 CYS H O 1 ATOM 4767 C CB . CYS C 3 152 ? 4.990 -7.529 27.999 1.00 132.38 ? 152 CYS H CB 1 ATOM 4768 S SG . CYS C 3 152 ? 6.072 -6.188 28.553 1.00 132.38 ? 152 CYS H SG 1 ATOM 4769 N N . LEU C 3 153 ? 4.949 -10.841 27.765 1.00 63.25 ? 153 LEU H N 1 ATOM 4770 C CA . LEU C 3 153 ? 4.175 -11.983 27.303 1.00 63.25 ? 153 LEU H CA 1 ATOM 4771 C C . LEU C 3 153 ? 2.940 -11.889 28.160 1.00 63.25 ? 153 LEU H C 1 ATOM 4772 O O . LEU C 3 153 ? 3.014 -11.897 29.339 1.00 63.25 ? 153 LEU H O 1 ATOM 4773 C CB . LEU C 3 153 ? 4.909 -13.285 27.554 1.00 47.20 ? 153 LEU H CB 1 ATOM 4774 C CG . LEU C 3 153 ? 4.079 -14.446 27.064 1.00 47.20 ? 153 LEU H CG 1 ATOM 4775 C CD1 . LEU C 3 153 ? 3.967 -14.212 25.646 1.00 47.20 ? 153 LEU H CD1 1 ATOM 4776 C CD2 . LEU C 3 153 ? 4.718 -15.784 27.222 1.00 47.20 ? 153 LEU H CD2 1 ATOM 4777 N N . VAL C 3 154 ? 1.771 -11.827 27.602 1.00 59.21 ? 154 VAL H N 1 ATOM 4778 C CA . VAL C 3 154 ? 0.631 -11.649 28.468 1.00 59.21 ? 154 VAL H CA 1 ATOM 4779 C C . VAL C 3 154 ? -0.023 -12.997 28.341 1.00 59.21 ? 154 VAL H C 1 ATOM 4780 O O . VAL C 3 154 ? -0.487 -13.364 27.238 1.00 59.21 ? 154 VAL H O 1 ATOM 4781 C CB . VAL C 3 154 ? -0.300 -10.528 27.961 1.00 12.02 ? 154 VAL H CB 1 ATOM 4782 C CG1 . VAL C 3 154 ? -1.500 -10.397 28.944 1.00 12.02 ? 154 VAL H CG1 1 ATOM 4783 C CG2 . VAL C 3 154 ? 0.427 -9.215 27.933 1.00 12.02 ? 154 VAL H CG2 1 ATOM 4784 N N . LYS C 3 155 ? -0.195 -13.657 29.494 1.00 66.44 ? 155 LYS H N 1 ATOM 4785 C CA . LYS C 3 155 ? -0.578 -15.048 29.506 1.00 66.44 ? 155 LYS H CA 1 ATOM 4786 C C . LYS C 3 155 ? -1.869 -15.527 30.169 1.00 66.44 ? 155 LYS H C 1 ATOM 4787 O O . LYS C 3 155 ? -2.324 -14.859 31.041 1.00 66.44 ? 155 LYS H O 1 ATOM 4788 C CB . LYS C 3 155 ? 0.593 -15.828 30.059 1.00 84.88 ? 155 LYS H CB 1 ATOM 4789 C CG . LYS C 3 155 ? 0.383 -17.315 30.139 1.00 84.88 ? 155 LYS H CG 1 ATOM 4790 C CD . LYS C 3 155 ? 0.244 -17.772 28.633 1.00 84.88 ? 155 LYS H CD 1 ATOM 4791 C CE . LYS C 3 155 ? 0.110 -19.288 28.379 1.00 84.88 ? 155 LYS H CE 1 ATOM 4792 N NZ . LYS C 3 155 ? -0.003 -19.656 26.914 1.00 84.88 ? 155 LYS H NZ 1 ATOM 4793 N N . ASP C 3 156 ? -2.597 -16.478 29.583 1.00 95.49 ? 156 ASP H N 1 ATOM 4794 C CA . ASP C 3 156 ? -3.674 -17.081 30.367 1.00 95.49 ? 156 ASP H CA 1 ATOM 4795 C C . ASP C 3 156 ? -4.820 -16.260 30.993 1.00 95.49 ? 156 ASP H C 1 ATOM 4796 O O . ASP C 3 156 ? -5.089 -16.405 32.180 1.00 95.49 ? 156 ASP H O 1 ATOM 4797 C CB . ASP C 3 156 ? -2.984 -17.883 31.497 1.00 123.60 ? 156 ASP H CB 1 ATOM 4798 C CG . ASP C 3 156 ? -2.245 -19.137 31.006 1.00 123.60 ? 156 ASP H CG 1 ATOM 4799 O OD1 . ASP C 3 156 ? -2.632 -19.701 29.964 1.00 123.60 ? 156 ASP H OD1 1 ATOM 4800 O OD2 . ASP C 3 156 ? -1.253 -19.546 31.662 1.00 123.60 ? 156 ASP H OD2 1 ATOM 4801 N N . TYR C 3 157 ? -5.486 -15.390 30.243 1.00 76.53 ? 157 TYR H N 1 ATOM 4802 C CA . TYR C 3 157 ? -6.562 -14.568 30.825 1.00 76.53 ? 157 TYR H CA 1 ATOM 4803 C C . TYR C 3 157 ? -7.880 -14.573 30.028 1.00 76.53 ? 157 TYR H C 1 ATOM 4804 O O . TYR C 3 157 ? -7.830 -14.862 28.841 1.00 76.53 ? 157 TYR H O 1 ATOM 4805 C CB . TYR C 3 157 ? -6.027 -13.151 30.855 1.00 117.84 ? 157 TYR H CB 1 ATOM 4806 C CG . TYR C 3 157 ? -5.900 -12.543 29.459 1.00 117.84 ? 157 TYR H CG 1 ATOM 4807 C CD1 . TYR C 3 157 ? -6.930 -11.839 28.866 1.00 117.84 ? 157 TYR H CD1 1 ATOM 4808 C CD2 . TYR C 3 157 ? -4.779 -12.783 28.685 1.00 117.84 ? 157 TYR H CD2 1 ATOM 4809 C CE1 . TYR C 3 157 ? -6.825 -11.393 27.570 1.00 117.84 ? 157 TYR H CE1 1 ATOM 4810 C CE2 . TYR C 3 157 ? -4.704 -12.344 27.383 1.00 117.84 ? 157 TYR H CE2 1 ATOM 4811 C CZ . TYR C 3 157 ? -5.721 -11.657 26.857 1.00 117.84 ? 157 TYR H CZ 1 ATOM 4812 O OH . TYR C 3 157 ? -5.616 -11.232 25.588 1.00 117.84 ? 157 TYR H OH 1 ATOM 4813 N N . PHE C 3 158 ? -9.033 -14.352 30.707 1.00 106.94 ? 158 PHE H N 1 ATOM 4814 C CA . PHE C 3 158 ? -10.355 -14.262 30.059 1.00 106.94 ? 158 PHE H CA 1 ATOM 4815 C C . PHE C 3 158 ? -10.974 -12.890 29.782 1.00 106.94 ? 158 PHE H C 1 ATOM 4816 O O . PHE C 3 158 ? -10.334 -11.883 30.074 1.00 106.94 ? 158 PHE H O 1 ATOM 4817 C CB . PHE C 3 158 ? -11.385 -15.256 30.598 1.00 62.59 ? 158 PHE H CB 1 ATOM 4818 C CG . PHE C 3 158 ? -12.365 -15.715 29.524 1.00 62.59 ? 158 PHE H CG 1 ATOM 4819 C CD1 . PHE C 3 158 ? -13.685 -15.312 29.495 1.00 62.59 ? 158 PHE H CD1 1 ATOM 4820 C CD2 . PHE C 3 158 ? -11.910 -16.477 28.510 1.00 62.59 ? 158 PHE H CD2 1 ATOM 4821 C CE1 . PHE C 3 158 ? -14.513 -15.651 28.498 1.00 62.59 ? 158 PHE H CE1 1 ATOM 4822 C CE2 . PHE C 3 158 ? -12.732 -16.828 27.482 1.00 62.59 ? 158 PHE H CE2 1 ATOM 4823 C CZ . PHE C 3 158 ? -14.054 -16.409 27.477 1.00 62.59 ? 158 PHE H CZ 1 ATOM 4824 N N . PRO C 3 159 ? -12.261 -12.831 29.380 1.00 118.78 ? 159 PRO H N 1 ATOM 4825 C CA . PRO C 3 159 ? -13.090 -11.704 28.979 1.00 118.78 ? 159 PRO H CA 1 ATOM 4826 C C . PRO C 3 159 ? -12.096 -11.005 28.082 1.00 118.78 ? 159 PRO H C 1 ATOM 4827 O O . PRO C 3 159 ? -11.167 -10.374 28.555 1.00 118.78 ? 159 PRO H O 1 ATOM 4828 C CB . PRO C 3 159 ? -13.385 -10.964 30.283 1.00 88.26 ? 159 PRO H CB 1 ATOM 4829 C CG . PRO C 3 159 ? -12.604 -11.661 31.317 1.00 88.26 ? 159 PRO H CG 1 ATOM 4830 C CD . PRO C 3 159 ? -12.668 -13.041 30.770 1.00 88.26 ? 159 PRO H CD 1 ATOM 4831 N N . GLU C 3 160 ? -12.332 -11.077 26.783 1.00 173.29 ? 160 GLU H N 1 ATOM 4832 C CA . GLU C 3 160 ? -11.400 -10.570 25.788 1.00 173.29 ? 160 GLU H CA 1 ATOM 4833 C C . GLU C 3 160 ? -11.658 -9.205 25.153 1.00 173.29 ? 160 GLU H C 1 ATOM 4834 O O . GLU C 3 160 ? -12.669 -9.006 24.451 1.00 173.29 ? 160 GLU H O 1 ATOM 4835 C CB . GLU C 3 160 ? -11.272 -11.659 24.699 1.00 116.59 ? 160 GLU H CB 1 ATOM 4836 C CG . GLU C 3 160 ? -10.541 -11.330 23.400 1.00 116.59 ? 160 GLU H CG 1 ATOM 4837 C CD . GLU C 3 160 ? -9.190 -10.739 23.577 1.00 116.59 ? 160 GLU H CD 1 ATOM 4838 O OE1 . GLU C 3 160 ? -8.214 -11.429 23.231 1.00 116.59 ? 160 GLU H OE1 1 ATOM 4839 O OE2 . GLU C 3 160 ? -9.104 -9.584 24.049 1.00 116.59 ? 160 GLU H OE2 1 ATOM 4840 N N . PRO C 3 161 ? -10.767 -8.228 25.470 1.00 74.55 ? 161 PRO H N 1 ATOM 4841 C CA . PRO C 3 161 ? -10.185 -6.881 25.426 1.00 74.55 ? 161 PRO H CA 1 ATOM 4842 C C . PRO C 3 161 ? -9.134 -6.719 26.488 1.00 74.55 ? 161 PRO H C 1 ATOM 4843 O O . PRO C 3 161 ? -9.474 -6.669 27.654 1.00 74.55 ? 161 PRO H O 1 ATOM 4844 C CB . PRO C 3 161 ? -11.353 -5.942 25.736 1.00 64.76 ? 161 PRO H CB 1 ATOM 4845 C CG . PRO C 3 161 ? -12.463 -6.846 26.327 1.00 64.76 ? 161 PRO H CG 1 ATOM 4846 C CD . PRO C 3 161 ? -11.723 -8.163 26.594 1.00 64.76 ? 161 PRO H CD 1 ATOM 4847 N N . VAL C 3 162 ? -7.857 -6.695 26.111 1.00 96.23 ? 162 VAL H N 1 ATOM 4848 C CA . VAL C 3 162 ? -6.723 -6.466 27.047 1.00 96.23 ? 162 VAL H CA 1 ATOM 4849 C C . VAL C 3 162 ? -5.818 -5.420 26.355 1.00 96.23 ? 162 VAL H C 1 ATOM 4850 O O . VAL C 3 162 ? -5.607 -5.477 25.162 1.00 96.23 ? 162 VAL H O 1 ATOM 4851 C CB . VAL C 3 162 ? -5.927 -7.775 27.438 1.00 94.07 ? 162 VAL H CB 1 ATOM 4852 C CG1 . VAL C 3 162 ? -5.160 -8.329 26.282 1.00 94.07 ? 162 VAL H CG1 1 ATOM 4853 C CG2 . VAL C 3 162 ? -5.007 -7.474 28.540 1.00 94.07 ? 162 VAL H CG2 1 ATOM 4854 N N . THR C 3 163 ? -5.270 -4.470 27.080 1.00 74.67 ? 163 THR H N 1 ATOM 4855 C CA . THR C 3 163 ? -4.529 -3.434 26.403 1.00 74.67 ? 163 THR H CA 1 ATOM 4856 C C . THR C 3 163 ? -3.123 -3.095 26.887 1.00 74.67 ? 163 THR H C 1 ATOM 4857 O O . THR C 3 163 ? -2.823 -3.172 28.068 1.00 74.67 ? 163 THR H O 1 ATOM 4858 C CB . THR C 3 163 ? -5.400 -2.147 26.414 1.00 55.44 ? 163 THR H CB 1 ATOM 4859 O OG1 . THR C 3 163 ? -5.696 -1.761 27.758 1.00 55.44 ? 163 THR H OG1 1 ATOM 4860 C CG2 . THR C 3 163 ? -6.663 -2.348 25.703 1.00 55.44 ? 163 THR H CG2 1 ATOM 4861 N N . VAL C 3 164 ? -2.301 -2.656 25.939 1.00 71.55 ? 164 VAL H N 1 ATOM 4862 C CA . VAL C 3 164 ? -0.879 -2.331 26.082 1.00 71.55 ? 164 VAL H CA 1 ATOM 4863 C C . VAL C 3 164 ? -0.258 -0.986 25.816 1.00 71.55 ? 164 VAL H C 1 ATOM 4864 O O . VAL C 3 164 ? -0.477 -0.392 24.783 1.00 71.55 ? 164 VAL H O 1 ATOM 4865 C CB . VAL C 3 164 ? -0.017 -3.340 25.375 1.00 45.04 ? 164 VAL H CB 1 ATOM 4866 C CG1 . VAL C 3 164 ? 1.422 -2.960 25.553 1.00 45.04 ? 164 VAL H CG1 1 ATOM 4867 C CG2 . VAL C 3 164 ? -0.200 -4.689 26.012 1.00 45.04 ? 164 VAL H CG2 1 ATOM 4868 N N . SER C 3 165 ? 0.525 -0.503 26.760 1.00 81.40 ? 165 SER H N 1 ATOM 4869 C CA . SER C 3 165 ? 1.189 0.789 26.618 1.00 81.40 ? 165 SER H CA 1 ATOM 4870 C C . SER C 3 165 ? 2.591 0.676 27.147 1.00 81.40 ? 165 SER H C 1 ATOM 4871 O O . SER C 3 165 ? 2.832 -0.047 28.093 1.00 81.40 ? 165 SER H O 1 ATOM 4872 C CB . SER C 3 165 ? 0.477 1.860 27.476 1.00 110.01 ? 165 SER H CB 1 ATOM 4873 O OG . SER C 3 165 ? 0.660 1.642 28.886 1.00 110.01 ? 165 SER H OG 1 ATOM 4874 N N . TRP C 3 166 ? 3.511 1.472 26.621 1.00 86.62 ? 166 TRP H N 1 ATOM 4875 C CA . TRP C 3 166 ? 4.872 1.393 27.150 1.00 86.62 ? 166 TRP H CA 1 ATOM 4876 C C . TRP C 3 166 ? 5.184 2.792 27.687 1.00 86.62 ? 166 TRP H C 1 ATOM 4877 O O . TRP C 3 166 ? 4.942 3.785 27.021 1.00 86.62 ? 166 TRP H O 1 ATOM 4878 C CB . TRP C 3 166 ? 5.766 1.015 25.992 1.00 85.16 ? 166 TRP H CB 1 ATOM 4879 C CG . TRP C 3 166 ? 5.505 -0.361 25.605 1.00 85.16 ? 166 TRP H CG 1 ATOM 4880 C CD1 . TRP C 3 166 ? 4.495 -0.793 24.848 1.00 85.16 ? 166 TRP H CD1 1 ATOM 4881 C CD2 . TRP C 3 166 ? 6.320 -1.489 25.876 1.00 85.16 ? 166 TRP H CD2 1 ATOM 4882 N NE1 . TRP C 3 166 ? 4.620 -2.123 24.611 1.00 85.16 ? 166 TRP H NE1 1 ATOM 4883 C CE2 . TRP C 3 166 ? 5.748 -2.573 25.237 1.00 85.16 ? 166 TRP H CE2 1 ATOM 4884 C CE3 . TRP C 3 166 ? 7.483 -1.689 26.606 1.00 85.16 ? 166 TRP H CE3 1 ATOM 4885 C CZ2 . TRP C 3 166 ? 6.308 -3.851 25.296 1.00 85.16 ? 166 TRP H CZ2 1 ATOM 4886 C CZ3 . TRP C 3 166 ? 8.034 -2.962 26.669 1.00 85.16 ? 166 TRP H CZ3 1 ATOM 4887 C CH2 . TRP C 3 166 ? 7.454 -4.018 26.023 1.00 85.16 ? 166 TRP H CH2 1 ATOM 4888 N N . ASN C 3 167 ? 5.852 2.843 28.825 1.00 119.70 ? 167 ASN H N 1 ATOM 4889 C CA . ASN C 3 167 ? 6.070 4.089 29.542 1.00 119.70 ? 167 ASN H CA 1 ATOM 4890 C C . ASN C 3 167 ? 4.710 4.781 29.680 1.00 119.70 ? 167 ASN H C 1 ATOM 4891 O O . ASN C 3 167 ? 4.612 6.005 29.616 1.00 119.70 ? 167 ASN H O 1 ATOM 4892 C CB . ASN C 3 167 ? 6.983 4.999 28.762 1.00 128.86 ? 167 ASN H CB 1 ATOM 4893 C CG . ASN C 3 167 ? 8.360 4.506 28.715 1.00 128.86 ? 167 ASN H CG 1 ATOM 4894 O OD1 . ASN C 3 167 ? 8.750 3.698 29.588 1.00 128.86 ? 167 ASN H OD1 1 ATOM 4895 N ND2 . ASN C 3 167 ? 9.044 4.935 27.778 1.00 128.86 ? 167 ASN H ND2 1 ATOM 4896 N N . SER C 3 168 ? 3.662 4.011 29.947 1.00 125.42 ? 168 SER H N 1 ATOM 4897 C CA . SER C 3 168 ? 2.352 4.613 30.113 1.00 125.42 ? 168 SER H CA 1 ATOM 4898 C C . SER C 3 168 ? 2.049 5.553 28.932 1.00 125.42 ? 168 SER H C 1 ATOM 4899 O O . SER C 3 168 ? 1.502 6.626 29.126 1.00 125.42 ? 168 SER H O 1 ATOM 4900 C CB . SER C 3 168 ? 2.333 5.366 31.436 1.00 122.68 ? 168 SER H CB 1 ATOM 4901 O OG . SER C 3 168 ? 2.544 4.457 32.516 1.00 122.68 ? 168 SER H OG 1 ATOM 4902 N N . GLY C 3 169 ? 2.421 5.148 27.720 1.00 126.17 ? 169 GLY H N 1 ATOM 4903 C CA . GLY C 3 169 ? 2.224 5.950 26.513 1.00 126.17 ? 169 GLY H CA 1 ATOM 4904 C C . GLY C 3 169 ? 3.354 6.910 26.119 1.00 126.17 ? 169 GLY H C 1 ATOM 4905 O O . GLY C 3 169 ? 3.320 7.515 25.048 1.00 126.17 ? 169 GLY H O 1 ATOM 4906 N N . ALA C 3 170 ? 4.341 7.107 26.990 1.00 148.77 ? 170 ALA H N 1 ATOM 4907 C CA . ALA C 3 170 ? 5.461 7.982 26.631 1.00 148.77 ? 170 ALA H CA 1 ATOM 4908 C C . ALA C 3 170 ? 6.204 7.472 25.388 1.00 148.77 ? 170 ALA H C 1 ATOM 4909 O O . ALA C 3 170 ? 6.548 8.262 24.507 1.00 148.77 ? 170 ALA H O 1 ATOM 4910 C CB . ALA C 3 170 ? 6.455 8.139 27.829 1.00 72.34 ? 170 ALA H CB 1 ATOM 4911 N N . LEU C 3 171 ? 6.422 6.154 25.291 1.00 114.46 ? 171 LEU H N 1 ATOM 4912 C CA . LEU C 3 171 ? 7.117 5.626 24.120 1.00 114.46 ? 171 LEU H CA 1 ATOM 4913 C C . LEU C 3 171 ? 6.105 4.960 23.220 1.00 114.46 ? 171 LEU H C 1 ATOM 4914 O O . LEU C 3 171 ? 5.662 3.862 23.506 1.00 114.46 ? 171 LEU H O 1 ATOM 4915 C CB . LEU C 3 171 ? 8.087 4.584 24.632 1.00 105.20 ? 171 LEU H CB 1 ATOM 4916 C CG . LEU C 3 171 ? 9.017 3.795 23.747 1.00 105.20 ? 171 LEU H CG 1 ATOM 4917 C CD1 . LEU C 3 171 ? 10.174 3.275 24.574 1.00 105.20 ? 171 LEU H CD1 1 ATOM 4918 C CD2 . LEU C 3 171 ? 8.260 2.647 23.136 1.00 105.20 ? 171 LEU H CD2 1 ATOM 4919 N N . THR C 3 172 ? 5.890 5.535 22.049 1.00 88.26 ? 172 THR H N 1 ATOM 4920 C CA . THR C 3 172 ? 4.910 5.026 21.105 1.00 88.26 ? 172 THR H CA 1 ATOM 4921 C C . THR C 3 172 ? 5.493 4.774 19.782 1.00 88.26 ? 172 THR H C 1 ATOM 4922 O O . THR C 3 172 ? 4.745 4.705 18.832 1.00 88.26 ? 172 THR H O 1 ATOM 4923 C CB . THR C 3 172 ? 3.792 5.991 20.916 1.00 145.04 ? 172 THR H CB 1 ATOM 4924 O OG1 . THR C 3 172 ? 4.365 7.275 20.643 1.00 145.04 ? 172 THR H OG1 1 ATOM 4925 C CG2 . THR C 3 172 ? 2.907 6.027 22.118 1.00 145.04 ? 172 THR H CG2 1 ATOM 4926 N N . SER C 3 173 ? 6.804 4.628 19.675 1.00 126.32 ? 173 SER H N 1 ATOM 4927 C CA . SER C 3 173 ? 7.380 4.488 18.347 1.00 126.32 ? 173 SER H CA 1 ATOM 4928 C C . SER C 3 173 ? 8.096 3.162 18.141 1.00 126.32 ? 173 SER H C 1 ATOM 4929 O O . SER C 3 173 ? 9.025 2.808 18.877 1.00 126.32 ? 173 SER H O 1 ATOM 4930 C CB . SER C 3 173 ? 8.356 5.655 18.154 1.00 94.73 ? 173 SER H CB 1 ATOM 4931 O OG . SER C 3 173 ? 9.104 5.556 16.938 1.00 94.73 ? 173 SER H OG 1 ATOM 4932 N N . GLY C 3 174 ? 7.749 2.501 17.033 1.00 63.13 ? 174 GLY H N 1 ATOM 4933 C CA . GLY C 3 174 ? 8.309 1.186 16.811 1.00 63.13 ? 174 GLY H CA 1 ATOM 4934 C C . GLY C 3 174 ? 7.727 0.155 17.769 1.00 63.13 ? 174 GLY H C 1 ATOM 4935 O O . GLY C 3 174 ? 8.393 -0.821 18.173 1.00 63.13 ? 174 GLY H O 1 ATOM 4936 N N . VAL C 3 175 ? 6.471 0.423 18.146 1.00 103.63 ? 175 VAL H N 1 ATOM 4937 C CA . VAL C 3 175 ? 5.656 -0.393 19.057 1.00 103.63 ? 175 VAL H CA 1 ATOM 4938 C C . VAL C 3 175 ? 4.512 -1.094 18.329 1.00 103.63 ? 175 VAL H C 1 ATOM 4939 O O . VAL C 3 175 ? 3.616 -0.451 17.785 1.00 103.63 ? 175 VAL H O 1 ATOM 4940 C CB . VAL C 3 175 ? 4.946 0.490 20.084 1.00 94.70 ? 175 VAL H CB 1 ATOM 4941 C CG1 . VAL C 3 175 ? 4.126 -0.363 20.995 1.00 94.70 ? 175 VAL H CG1 1 ATOM 4942 C CG2 . VAL C 3 175 ? 5.932 1.346 20.839 1.00 94.70 ? 175 VAL H CG2 1 ATOM 4943 N N . HIS C 3 176 ? 4.526 -2.416 18.397 1.00 107.26 ? 176 HIS H N 1 ATOM 4944 C CA . HIS C 3 176 ? 3.502 -3.278 17.807 1.00 107.26 ? 176 HIS H CA 1 ATOM 4945 C C . HIS C 3 176 ? 3.003 -4.305 18.863 1.00 107.26 ? 176 HIS H C 1 ATOM 4946 O O . HIS C 3 176 ? 3.823 -4.890 19.548 1.00 107.26 ? 176 HIS H O 1 ATOM 4947 C CB . HIS C 3 176 ? 4.032 -4.018 16.563 1.00 65.08 ? 176 HIS H CB 1 ATOM 4948 C CG . HIS C 3 176 ? 3.015 -4.906 15.934 1.00 65.08 ? 176 HIS H CG 1 ATOM 4949 N ND1 . HIS C 3 176 ? 2.860 -6.216 16.321 1.00 65.08 ? 176 HIS H ND1 1 ATOM 4950 C CD2 . HIS C 3 176 ? 2.056 -4.667 15.004 1.00 65.08 ? 176 HIS H CD2 1 ATOM 4951 C CE1 . HIS C 3 176 ? 1.839 -6.743 15.668 1.00 65.08 ? 176 HIS H CE1 1 ATOM 4952 N NE2 . HIS C 3 176 ? 1.333 -5.824 14.861 1.00 65.08 ? 176 HIS H NE2 1 ATOM 4953 N N . THR C 3 177 ? 1.687 -4.520 19.027 1.00 68.09 ? 177 THR H N 1 ATOM 4954 C CA . THR C 3 177 ? 1.192 -5.496 20.011 1.00 68.09 ? 177 THR H CA 1 ATOM 4955 C C . THR C 3 177 ? 0.408 -6.507 19.176 1.00 68.09 ? 177 THR H C 1 ATOM 4956 O O . THR C 3 177 ? -0.429 -6.138 18.392 1.00 68.09 ? 177 THR H O 1 ATOM 4957 C CB . THR C 3 177 ? 0.200 -4.885 21.085 1.00 54.24 ? 177 THR H CB 1 ATOM 4958 O OG1 . THR C 3 177 ? 0.829 -3.843 21.835 1.00 54.24 ? 177 THR H OG1 1 ATOM 4959 C CG2 . THR C 3 177 ? -0.117 -5.960 22.147 1.00 54.24 ? 177 THR H CG2 1 ATOM 4960 N N . PHE C 3 178 ? 0.674 -7.788 19.354 1.00 87.61 ? 178 PHE H N 1 ATOM 4961 C CA . PHE C 3 178 ? 0.017 -8.835 18.585 1.00 87.61 ? 178 PHE H CA 1 ATOM 4962 C C . PHE C 3 178 ? -1.426 -9.197 18.734 1.00 87.61 ? 178 PHE H C 1 ATOM 4963 O O . PHE C 3 178 ? -2.050 -8.928 19.750 1.00 87.61 ? 178 PHE H O 1 ATOM 4964 C CB . PHE C 3 178 ? 0.809 -10.133 18.672 1.00 86.79 ? 178 PHE H CB 1 ATOM 4965 C CG . PHE C 3 178 ? 2.063 -10.091 17.919 1.00 86.79 ? 178 PHE H CG 1 ATOM 4966 C CD1 . PHE C 3 178 ? 2.039 -10.407 16.579 1.00 86.79 ? 178 PHE H CD1 1 ATOM 4967 C CD2 . PHE C 3 178 ? 3.217 -9.596 18.451 1.00 86.79 ? 178 PHE H CD2 1 ATOM 4968 C CE1 . PHE C 3 178 ? 3.129 -10.219 15.777 1.00 86.79 ? 178 PHE H CE1 1 ATOM 4969 C CE2 . PHE C 3 178 ? 4.331 -9.402 17.644 1.00 86.79 ? 178 PHE H CE2 1 ATOM 4970 C CZ . PHE C 3 178 ? 4.263 -9.716 16.304 1.00 86.79 ? 178 PHE H CZ 1 ATOM 4971 N N . PRO C 3 179 ? -2.018 -9.734 17.662 1.00 93.66 ? 179 PRO H N 1 ATOM 4972 C CA . PRO C 3 179 ? -3.413 -10.103 17.815 1.00 93.66 ? 179 PRO H CA 1 ATOM 4973 C C . PRO C 3 179 ? -3.308 -11.159 18.877 1.00 93.66 ? 179 PRO H C 1 ATOM 4974 O O . PRO C 3 179 ? -2.267 -11.804 18.987 1.00 93.66 ? 179 PRO H O 1 ATOM 4975 C CB . PRO C 3 179 ? -3.747 -10.694 16.465 1.00 167.88 ? 179 PRO H CB 1 ATOM 4976 C CG . PRO C 3 179 ? -2.490 -11.413 16.127 1.00 167.88 ? 179 PRO H CG 1 ATOM 4977 C CD . PRO C 3 179 ? -1.436 -10.389 16.482 1.00 167.88 ? 179 PRO H CD 1 ATOM 4978 N N . ALA C 3 180 ? -4.368 -11.363 19.644 1.00 86.97 ? 180 ALA H N 1 ATOM 4979 C CA . ALA C 3 180 ? -4.312 -12.359 20.701 1.00 86.97 ? 180 ALA H CA 1 ATOM 4980 C C . ALA C 3 180 ? -4.514 -13.763 20.155 1.00 86.97 ? 180 ALA H C 1 ATOM 4981 O O . ALA C 3 180 ? -5.040 -13.958 19.088 1.00 86.97 ? 180 ALA H O 1 ATOM 4982 C CB . ALA C 3 180 ? -5.349 -12.040 21.783 1.00 123.26 ? 180 ALA H CB 1 ATOM 4983 N N . VAL C 3 181 ? -4.060 -14.733 20.905 1.00 90.60 ? 181 VAL H N 1 ATOM 4984 C CA . VAL C 3 181 ? -4.137 -16.126 20.585 1.00 90.60 ? 181 VAL H CA 1 ATOM 4985 C C . VAL C 3 181 ? -4.905 -16.843 21.618 1.00 90.60 ? 181 VAL H C 1 ATOM 4986 O O . VAL C 3 181 ? -4.616 -16.673 22.771 1.00 90.60 ? 181 VAL H O 1 ATOM 4987 C CB . VAL C 3 181 ? -2.773 -16.755 20.470 1.00 55.02 ? 181 VAL H CB 1 ATOM 4988 C CG1 . VAL C 3 181 ? -1.829 -16.249 21.525 1.00 55.02 ? 181 VAL H CG1 1 ATOM 4989 C CG2 . VAL C 3 181 ? -2.948 -18.274 20.686 1.00 55.02 ? 181 VAL H CG2 1 ATOM 4990 N N . LEU C 3 182 ? -5.882 -17.658 21.249 1.00 153.10 ? 182 LEU H N 1 ATOM 4991 C CA . LEU C 3 182 ? -6.666 -18.348 22.272 1.00 153.10 ? 182 LEU H CA 1 ATOM 4992 C C . LEU C 3 182 ? -6.204 -19.779 22.488 1.00 153.10 ? 182 LEU H C 1 ATOM 4993 O O . LEU C 3 182 ? -6.135 -20.628 21.599 1.00 153.10 ? 182 LEU H O 1 ATOM 4994 C CB . LEU C 3 182 ? -8.144 -18.320 21.925 1.00 99.20 ? 182 LEU H CB 1 ATOM 4995 C CG . LEU C 3 182 ? -9.052 -19.012 22.925 1.00 99.20 ? 182 LEU H CG 1 ATOM 4996 C CD1 . LEU C 3 182 ? -10.473 -18.403 22.971 1.00 99.20 ? 182 LEU H CD1 1 ATOM 4997 C CD2 . LEU C 3 182 ? -9.118 -20.487 22.479 1.00 99.20 ? 182 LEU H CD2 1 ATOM 4998 N N . GLN C 3 183 ? -5.869 -19.970 23.753 1.00 101.56 ? 183 GLN H N 1 ATOM 4999 C CA . GLN C 3 183 ? -5.304 -21.155 24.366 1.00 101.56 ? 183 GLN H CA 1 ATOM 5000 C C . GLN C 3 183 ? -6.371 -22.250 24.623 1.00 101.56 ? 183 GLN H C 1 ATOM 5001 O O . GLN C 3 183 ? -7.572 -21.996 24.722 1.00 101.56 ? 183 GLN H O 1 ATOM 5002 C CB . GLN C 3 183 ? -4.557 -20.721 25.665 1.00 114.85 ? 183 GLN H CB 1 ATOM 5003 C CG . GLN C 3 183 ? -3.708 -21.781 26.328 1.00 114.85 ? 183 GLN H CG 1 ATOM 5004 C CD . GLN C 3 183 ? -2.447 -22.119 25.488 1.00 114.85 ? 183 GLN H CD 1 ATOM 5005 O OE1 . GLN C 3 183 ? -1.510 -21.306 25.358 1.00 114.85 ? 183 GLN H OE1 1 ATOM 5006 N NE2 . GLN C 3 183 ? -2.428 -23.322 24.912 1.00 114.85 ? 183 GLN H NE2 1 ATOM 5007 N N . SER C 3 184 ? -5.891 -23.481 24.670 1.00 103.10 ? 184 SER H N 1 ATOM 5008 C CA . SER C 3 184 ? -6.690 -24.674 24.915 1.00 103.10 ? 184 SER H CA 1 ATOM 5009 C C . SER C 3 184 ? -7.267 -24.605 26.340 1.00 103.10 ? 184 SER H C 1 ATOM 5010 O O . SER C 3 184 ? -8.290 -25.213 26.642 1.00 103.10 ? 184 SER H O 1 ATOM 5011 C CB . SER C 3 184 ? -5.765 -25.892 24.737 1.00 89.76 ? 184 SER H CB 1 ATOM 5012 O OG . SER C 3 184 ? -4.688 -25.828 25.663 1.00 89.76 ? 184 SER H OG 1 ATOM 5013 N N . SER C 3 185 ? -6.642 -23.778 27.172 1.00 105.99 ? 185 SER H N 1 ATOM 5014 C CA . SER C 3 185 ? -6.998 -23.552 28.590 1.00 105.99 ? 185 SER H CA 1 ATOM 5015 C C . SER C 3 185 ? -8.417 -23.038 28.568 1.00 105.99 ? 185 SER H C 1 ATOM 5016 O O . SER C 3 185 ? -9.234 -23.354 29.409 1.00 105.99 ? 185 SER H O 1 ATOM 5017 C CB . SER C 3 185 ? -6.107 -22.455 29.242 1.00 96.26 ? 185 SER H CB 1 ATOM 5018 O OG . SER C 3 185 ? -4.719 -22.815 29.369 1.00 96.26 ? 185 SER H OG 1 ATOM 5019 N N . GLY C 3 186 ? -8.664 -22.194 27.595 1.00 67.33 ? 186 GLY H N 1 ATOM 5020 C CA . GLY C 3 186 ? -9.939 -21.545 27.473 1.00 67.33 ? 186 GLY H CA 1 ATOM 5021 C C . GLY C 3 186 ? -9.625 -20.084 27.725 1.00 67.33 ? 186 GLY H C 1 ATOM 5022 O O . GLY C 3 186 ? -10.516 -19.237 27.800 1.00 67.33 ? 186 GLY H O 1 ATOM 5023 N N . LEU C 3 187 ? -8.332 -19.807 27.914 1.00 111.80 ? 187 LEU H N 1 ATOM 5024 C CA . LEU C 3 187 ? -7.847 -18.452 28.124 1.00 111.80 ? 187 LEU H CA 1 ATOM 5025 C C . LEU C 3 187 ? -6.998 -17.838 26.992 1.00 111.80 ? 187 LEU H C 1 ATOM 5026 O O . LEU C 3 187 ? -5.984 -18.414 26.574 1.00 111.80 ? 187 LEU H O 1 ATOM 5027 C CB . LEU C 3 187 ? -7.014 -18.504 29.344 1.00 55.52 ? 187 LEU H CB 1 ATOM 5028 C CG . LEU C 3 187 ? -7.821 -18.833 30.544 1.00 55.52 ? 187 LEU H CG 1 ATOM 5029 C CD1 . LEU C 3 187 ? -6.929 -19.110 31.702 1.00 55.52 ? 187 LEU H CD1 1 ATOM 5030 C CD2 . LEU C 3 187 ? -8.711 -17.644 30.765 1.00 55.52 ? 187 LEU H CD2 1 ATOM 5031 N N . TYR C 3 188 ? -7.367 -16.626 26.577 1.00 69.02 ? 188 TYR H N 1 ATOM 5032 C CA . TYR C 3 188 ? -6.674 -15.865 25.512 1.00 69.02 ? 188 TYR H CA 1 ATOM 5033 C C . TYR C 3 188 ? -5.298 -15.388 25.997 1.00 69.02 ? 188 TYR H C 1 ATOM 5034 O O . TYR C 3 188 ? -5.166 -15.027 27.143 1.00 69.02 ? 188 TYR H O 1 ATOM 5035 C CB . TYR C 3 188 ? -7.471 -14.629 25.071 1.00 81.98 ? 188 TYR H CB 1 ATOM 5036 C CG . TYR C 3 188 ? -8.847 -14.911 24.509 1.00 81.98 ? 188 TYR H CG 1 ATOM 5037 C CD1 . TYR C 3 188 ? -9.056 -15.136 23.189 1.00 81.98 ? 188 TYR H CD1 1 ATOM 5038 C CD2 . TYR C 3 188 ? -9.956 -14.849 25.327 1.00 81.98 ? 188 TYR H CD2 1 ATOM 5039 C CE1 . TYR C 3 188 ? -10.335 -15.290 22.703 1.00 81.98 ? 188 TYR H CE1 1 ATOM 5040 C CE2 . TYR C 3 188 ? -11.228 -15.000 24.851 1.00 81.98 ? 188 TYR H CE2 1 ATOM 5041 C CZ . TYR C 3 188 ? -11.426 -15.218 23.549 1.00 81.98 ? 188 TYR H CZ 1 ATOM 5042 O OH . TYR C 3 188 ? -12.726 -15.336 23.112 1.00 81.98 ? 188 TYR H OH 1 ATOM 5043 N N . SER C 3 189 ? -4.285 -15.385 25.136 1.00 78.71 ? 189 SER H N 1 ATOM 5044 C CA . SER C 3 189 ? -2.946 -14.900 25.494 1.00 78.71 ? 189 SER H CA 1 ATOM 5045 C C . SER C 3 189 ? -2.410 -13.888 24.452 1.00 78.71 ? 189 SER H C 1 ATOM 5046 O O . SER C 3 189 ? -2.607 -14.013 23.276 1.00 78.71 ? 189 SER H O 1 ATOM 5047 C CB . SER C 3 189 ? -2.003 -16.091 25.607 1.00 58.87 ? 189 SER H CB 1 ATOM 5048 O OG . SER C 3 189 ? -2.494 -16.951 26.609 1.00 58.87 ? 189 SER H OG 1 ATOM 5049 N N . LEU C 3 190 ? -1.763 -12.860 24.934 1.00 80.40 ? 190 LEU H N 1 ATOM 5050 C CA . LEU C 3 190 ? -1.167 -11.762 24.187 1.00 80.40 ? 190 LEU H CA 1 ATOM 5051 C C . LEU C 3 190 ? 0.245 -11.250 24.318 1.00 80.40 ? 190 LEU H C 1 ATOM 5052 O O . LEU C 3 190 ? 0.597 -10.906 25.426 1.00 80.40 ? 190 LEU H O 1 ATOM 5053 C CB . LEU C 3 190 ? -2.033 -10.574 24.392 1.00 59.66 ? 190 LEU H CB 1 ATOM 5054 C CG . LEU C 3 190 ? -1.366 -9.326 23.856 1.00 59.66 ? 190 LEU H CG 1 ATOM 5055 C CD1 . LEU C 3 190 ? -1.044 -9.313 22.454 1.00 59.66 ? 190 LEU H CD1 1 ATOM 5056 C CD2 . LEU C 3 190 ? -2.294 -8.230 24.243 1.00 59.66 ? 190 LEU H CD2 1 ATOM 5057 N N . SER C 3 191 ? 1.039 -11.064 23.261 1.00 49.27 ? 191 SER H N 1 ATOM 5058 C CA . SER C 3 191 ? 2.373 -10.467 23.538 1.00 49.27 ? 191 SER H CA 1 ATOM 5059 C C . SER C 3 191 ? 2.625 -9.146 22.821 1.00 49.27 ? 191 SER H C 1 ATOM 5060 O O . SER C 3 191 ? 2.326 -8.991 21.671 1.00 49.27 ? 191 SER H O 1 ATOM 5061 C CB . SER C 3 191 ? 3.571 -11.417 23.297 1.00 62.65 ? 191 SER H CB 1 ATOM 5062 O OG . SER C 3 191 ? 3.766 -11.804 21.983 1.00 62.65 ? 191 SER H OG 1 ATOM 5063 N N . SER C 3 192 ? 3.250 -8.197 23.485 1.00 80.93 ? 192 SER H N 1 ATOM 5064 C CA . SER C 3 192 ? 3.435 -6.906 22.881 1.00 80.93 ? 192 SER H CA 1 ATOM 5065 C C . SER C 3 192 ? 4.937 -6.822 22.815 1.00 80.93 ? 192 SER H C 1 ATOM 5066 O O . SER C 3 192 ? 5.625 -7.013 23.790 1.00 80.93 ? 192 SER H O 1 ATOM 5067 C CB . SER C 3 192 ? 2.831 -5.889 23.825 1.00 63.18 ? 192 SER H CB 1 ATOM 5068 O OG . SER C 3 192 ? 2.952 -4.587 23.361 1.00 63.18 ? 192 SER H OG 1 ATOM 5069 N N . VAL C 3 193 ? 5.436 -6.519 21.625 1.00 84.20 ? 193 VAL H N 1 ATOM 5070 C CA . VAL C 3 193 ? 6.852 -6.501 21.304 1.00 84.20 ? 193 VAL H CA 1 ATOM 5071 C C . VAL C 3 193 ? 7.315 -5.233 20.648 1.00 84.20 ? 193 VAL H C 1 ATOM 5072 O O . VAL C 3 193 ? 6.669 -4.736 19.753 1.00 84.20 ? 193 VAL H O 1 ATOM 5073 C CB . VAL C 3 193 ? 7.247 -7.670 20.439 1.00 73.89 ? 193 VAL H CB 1 ATOM 5074 C CG1 . VAL C 3 193 ? 8.660 -7.576 20.169 1.00 73.89 ? 193 VAL H CG1 1 ATOM 5075 C CG2 . VAL C 3 193 ? 6.920 -8.969 21.081 1.00 73.89 ? 193 VAL H CG2 1 ATOM 5076 N N . VAL C 3 194 ? 8.377 -4.647 21.152 1.00 102.80 ? 194 VAL H N 1 ATOM 5077 C CA . VAL C 3 194 ? 8.940 -3.419 20.581 1.00 102.80 ? 194 VAL H CA 1 ATOM 5078 C C . VAL C 3 194 ? 10.469 -3.573 20.358 1.00 102.80 ? 194 VAL H C 1 ATOM 5079 O O . VAL C 3 194 ? 11.127 -4.256 21.147 1.00 102.80 ? 194 VAL H O 1 ATOM 5080 C CB . VAL C 3 194 ? 8.674 -2.239 21.522 1.00 103.17 ? 194 VAL H CB 1 ATOM 5081 C CG1 . VAL C 3 194 ? 9.289 -2.527 22.896 1.00 103.17 ? 194 VAL H CG1 1 ATOM 5082 C CG2 . VAL C 3 194 ? 9.265 -0.969 20.921 1.00 103.17 ? 194 VAL H CG2 1 ATOM 5083 N N . THR C 3 195 ? 11.018 -3.062 19.242 1.00 80.85 ? 195 THR H N 1 ATOM 5084 C CA . THR C 3 195 ? 12.477 -3.187 19.040 1.00 80.85 ? 195 THR H CA 1 ATOM 5085 C C . THR C 3 195 ? 13.137 -1.810 19.297 1.00 80.85 ? 195 THR H C 1 ATOM 5086 O O . THR C 3 195 ? 12.574 -0.762 18.967 1.00 80.85 ? 195 THR H O 1 ATOM 5087 C CB . THR C 3 195 ? 12.879 -3.701 17.574 1.00 87.25 ? 195 THR H CB 1 ATOM 5088 O OG1 . THR C 3 195 ? 12.394 -2.794 16.604 1.00 87.25 ? 195 THR H OG1 1 ATOM 5089 C CG2 . THR C 3 195 ? 12.312 -5.062 17.215 1.00 87.25 ? 195 THR H CG2 1 ATOM 5090 N N . VAL C 3 196 ? 14.337 -1.836 19.876 1.00 91.06 ? 196 VAL H N 1 ATOM 5091 C CA . VAL C 3 196 ? 15.061 -0.623 20.266 1.00 91.06 ? 196 VAL H CA 1 ATOM 5092 C C . VAL C 3 196 ? 16.547 -0.602 19.990 1.00 91.06 ? 196 VAL H C 1 ATOM 5093 O O . VAL C 3 196 ? 17.168 -1.643 19.824 1.00 91.06 ? 196 VAL H O 1 ATOM 5094 C CB . VAL C 3 196 ? 14.939 -0.380 21.767 1.00 110.93 ? 196 VAL H CB 1 ATOM 5095 C CG1 . VAL C 3 196 ? 13.526 -0.003 22.117 1.00 110.93 ? 196 VAL H CG1 1 ATOM 5096 C CG2 . VAL C 3 196 ? 15.387 -1.628 22.528 1.00 110.93 ? 196 VAL H CG2 1 ATOM 5097 N N . PRO C 3 197 ? 17.143 0.591 19.946 1.00 99.19 ? 197 PRO H N 1 ATOM 5098 C CA . PRO C 3 197 ? 18.593 0.674 19.697 1.00 99.19 ? 197 PRO H CA 1 ATOM 5099 C C . PRO C 3 197 ? 19.424 0.082 20.871 1.00 99.19 ? 197 PRO H C 1 ATOM 5100 O O . PRO C 3 197 ? 18.988 0.145 22.026 1.00 99.19 ? 197 PRO H O 1 ATOM 5101 C CB . PRO C 3 197 ? 18.818 2.176 19.499 1.00 75.60 ? 197 PRO H CB 1 ATOM 5102 C CG . PRO C 3 197 ? 17.619 2.818 20.281 1.00 75.60 ? 197 PRO H CG 1 ATOM 5103 C CD . PRO C 3 197 ? 16.498 1.915 19.905 1.00 75.60 ? 197 PRO H CD 1 ATOM 5104 N N . SER C 3 198 ? 20.528 -0.606 20.551 1.00 83.44 ? 198 SER H N 1 ATOM 5105 C CA . SER C 3 198 ? 21.426 -1.189 21.555 1.00 83.44 ? 198 SER H CA 1 ATOM 5106 C C . SER C 3 198 ? 22.046 -0.211 22.500 1.00 83.44 ? 198 SER H C 1 ATOM 5107 O O . SER C 3 198 ? 22.062 -0.456 23.688 1.00 83.44 ? 198 SER H O 1 ATOM 5108 C CB . SER C 3 198 ? 22.530 -1.987 20.908 1.00 97.52 ? 198 SER H CB 1 ATOM 5109 O OG . SER C 3 198 ? 21.976 -3.143 20.336 1.00 97.52 ? 198 SER H OG 1 ATOM 5110 N N . SER C 3 199 ? 22.442 0.944 21.970 1.00 109.46 ? 199 SER H N 1 ATOM 5111 C CA . SER C 3 199 ? 23.119 2.033 22.699 1.00 109.46 ? 199 SER H CA 1 ATOM 5112 C C . SER C 3 199 ? 22.193 2.495 23.807 1.00 109.46 ? 199 SER H C 1 ATOM 5113 O O . SER C 3 199 ? 22.627 2.950 24.865 1.00 109.46 ? 199 SER H O 1 ATOM 5114 C CB . SER C 3 199 ? 23.433 3.171 21.741 1.00 168.26 ? 199 SER H CB 1 ATOM 5115 O OG . SER C 3 199 ? 22.230 3.785 21.320 1.00 168.26 ? 199 SER H OG 1 ATOM 5116 N N . SER C 3 200 ? 20.915 2.494 23.466 1.00 114.65 ? 200 SER H N 1 ATOM 5117 C CA . SER C 3 200 ? 19.804 2.802 24.372 1.00 114.65 ? 200 SER H CA 1 ATOM 5118 C C . SER C 3 200 ? 19.698 1.879 25.575 1.00 114.65 ? 200 SER H C 1 ATOM 5119 O O . SER C 3 200 ? 19.380 2.336 26.659 1.00 114.65 ? 200 SER H O 1 ATOM 5120 C CB . SER C 3 200 ? 18.449 2.755 23.654 1.00 133.28 ? 200 SER H CB 1 ATOM 5121 O OG . SER C 3 200 ? 17.418 3.061 24.577 1.00 133.28 ? 200 SER H OG 1 ATOM 5122 N N . LEU C 3 201 ? 19.928 0.584 25.370 1.00 97.44 ? 201 LEU H N 1 ATOM 5123 C CA . LEU C 3 201 ? 19.726 -0.379 26.425 1.00 97.44 ? 201 LEU H CA 1 ATOM 5124 C C . LEU C 3 201 ? 20.516 -0.280 27.751 1.00 97.44 ? 201 LEU H C 1 ATOM 5125 O O . LEU C 3 201 ? 19.929 -0.487 28.804 1.00 97.44 ? 201 LEU H O 1 ATOM 5126 C CB . LEU C 3 201 ? 19.999 -1.762 25.831 1.00 80.94 ? 201 LEU H CB 1 ATOM 5127 C CG . LEU C 3 201 ? 18.980 -2.279 24.820 1.00 80.94 ? 201 LEU H CG 1 ATOM 5128 C CD1 . LEU C 3 201 ? 19.436 -3.544 24.125 1.00 80.94 ? 201 LEU H CD1 1 ATOM 5129 C CD2 . LEU C 3 201 ? 17.664 -2.500 25.548 1.00 80.94 ? 201 LEU H CD2 1 ATOM 5130 N N . GLY C 3 202 ? 21.799 0.053 27.774 1.00 123.65 ? 202 GLY H N 1 ATOM 5131 C CA . GLY C 3 202 ? 22.410 0.170 29.088 1.00 123.65 ? 202 GLY H CA 1 ATOM 5132 C C . GLY C 3 202 ? 21.768 1.324 29.838 1.00 123.65 ? 202 GLY H C 1 ATOM 5133 O O . GLY C 3 202 ? 21.266 1.208 30.956 1.00 123.65 ? 202 GLY H O 1 ATOM 5134 N N . THR C 3 203 ? 21.717 2.441 29.134 1.00 116.58 ? 203 THR H N 1 ATOM 5135 C CA . THR C 3 203 ? 21.184 3.691 29.626 1.00 116.58 ? 203 THR H CA 1 ATOM 5136 C C . THR C 3 203 ? 19.683 3.812 29.857 1.00 116.58 ? 203 THR H C 1 ATOM 5137 O O . THR C 3 203 ? 19.272 4.452 30.817 1.00 116.58 ? 203 THR H O 1 ATOM 5138 C CB . THR C 3 203 ? 21.676 4.857 28.740 1.00 140.35 ? 203 THR H CB 1 ATOM 5139 O OG1 . THR C 3 203 ? 21.054 4.799 27.439 1.00 140.35 ? 203 THR H OG1 1 ATOM 5140 C CG2 . THR C 3 203 ? 23.204 4.779 28.606 1.00 140.35 ? 203 THR H CG2 1 ATOM 5141 N N . GLN C 3 204 ? 18.867 3.249 28.967 1.00 155.14 ? 204 GLN H N 1 ATOM 5142 C CA . GLN C 3 204 ? 17.401 3.332 29.076 1.00 155.14 ? 204 GLN H CA 1 ATOM 5143 C C . GLN C 3 204 ? 16.592 2.123 29.590 1.00 155.14 ? 204 GLN H C 1 ATOM 5144 O O . GLN C 3 204 ? 16.773 0.990 29.152 1.00 155.14 ? 204 GLN H O 1 ATOM 5145 C CB . GLN C 3 204 ? 16.791 3.837 27.759 1.00 104.52 ? 204 GLN H CB 1 ATOM 5146 C CG . GLN C 3 204 ? 15.260 3.948 27.804 1.00 104.52 ? 204 GLN H CG 1 ATOM 5147 C CD . GLN C 3 204 ? 14.785 5.076 28.702 1.00 104.52 ? 204 GLN H CD 1 ATOM 5148 O OE1 . GLN C 3 204 ? 14.957 6.251 28.377 1.00 104.52 ? 204 GLN H OE1 1 ATOM 5149 N NE2 . GLN C 3 204 ? 14.197 4.722 29.856 1.00 104.52 ? 204 GLN H NE2 1 ATOM 5150 N N . THR C 3 205 ? 15.719 2.378 30.556 1.00 126.48 ? 205 THR H N 1 ATOM 5151 C CA . THR C 3 205 ? 14.874 1.350 31.138 1.00 126.48 ? 205 THR H CA 1 ATOM 5152 C C . THR C 3 205 ? 13.442 1.387 30.547 1.00 126.48 ? 205 THR H C 1 ATOM 5153 O O . THR C 3 205 ? 12.932 2.460 30.225 1.00 126.48 ? 205 THR H O 1 ATOM 5154 C CB . THR C 3 205 ? 14.931 1.488 32.698 1.00 93.49 ? 205 THR H CB 1 ATOM 5155 O OG1 . THR C 3 205 ? 14.692 2.861 33.074 1.00 93.49 ? 205 THR H OG1 1 ATOM 5156 C CG2 . THR C 3 205 ? 16.279 0.961 33.252 1.00 93.49 ? 205 THR H CG2 1 ATOM 5157 N N . TYR C 3 206 ? 12.816 0.207 30.375 1.00 115.73 ? 206 TYR H N 1 ATOM 5158 C CA . TYR C 3 206 ? 11.475 0.118 29.765 1.00 115.73 ? 206 TYR H CA 1 ATOM 5159 C C . TYR C 3 206 ? 10.327 -0.487 30.618 1.00 115.73 ? 206 TYR H C 1 ATOM 5160 O O . TYR C 3 206 ? 10.437 -1.589 31.142 1.00 115.73 ? 206 TYR H O 1 ATOM 5161 C CB . TYR C 3 206 ? 11.585 -0.781 28.535 1.00 87.47 ? 206 TYR H CB 1 ATOM 5162 C CG . TYR C 3 206 ? 12.535 -0.276 27.502 1.00 87.47 ? 206 TYR H CG 1 ATOM 5163 C CD1 . TYR C 3 206 ? 12.119 0.585 26.502 1.00 87.47 ? 206 TYR H CD1 1 ATOM 5164 C CD2 . TYR C 3 206 ? 13.847 -0.709 27.496 1.00 87.47 ? 206 TYR H CD2 1 ATOM 5165 C CE1 . TYR C 3 206 ? 12.983 1.017 25.512 1.00 87.47 ? 206 TYR H CE1 1 ATOM 5166 C CE2 . TYR C 3 206 ? 14.740 -0.297 26.509 1.00 87.47 ? 206 TYR H CE2 1 ATOM 5167 C CZ . TYR C 3 206 ? 14.297 0.576 25.514 1.00 87.47 ? 206 TYR H CZ 1 ATOM 5168 O OH . TYR C 3 206 ? 15.167 1.019 24.533 1.00 87.47 ? 206 TYR H OH 1 ATOM 5169 N N . ILE C 3 207 ? 9.198 0.195 30.677 1.00 93.60 ? 207 ILE H N 1 ATOM 5170 C CA . ILE C 3 207 ? 8.014 -0.349 31.338 1.00 93.60 ? 207 ILE H CA 1 ATOM 5171 C C . ILE C 3 207 ? 6.780 -0.515 30.459 1.00 93.60 ? 207 ILE H C 1 ATOM 5172 O O . ILE C 3 207 ? 6.347 0.421 29.764 1.00 93.60 ? 207 ILE H O 1 ATOM 5173 C CB . ILE C 3 207 ? 7.621 0.324 32.660 1.00 113.16 ? 207 ILE H CB 1 ATOM 5174 C CG1 . ILE C 3 207 ? 8.760 0.187 33.641 1.00 113.16 ? 207 ILE H CG1 1 ATOM 5175 C CG2 . ILE C 3 207 ? 6.265 -0.129 33.105 1.00 113.16 ? 207 ILE H CG2 1 ATOM 5176 C CD1 . ILE C 3 207 ? 8.602 1.002 34.944 1.00 113.16 ? 207 ILE H CD1 1 ATOM 5177 N N . CYS C 3 208 ? 6.175 -1.706 30.493 1.00 66.38 ? 208 CYS H N 1 ATOM 5178 C CA . CYS C 3 208 ? 5.035 -1.953 29.634 1.00 66.38 ? 208 CYS H CA 1 ATOM 5179 C C . CYS C 3 208 ? 3.946 -2.106 30.627 1.00 66.38 ? 208 CYS H C 1 ATOM 5180 O O . CYS C 3 208 ? 4.149 -2.617 31.674 1.00 66.38 ? 208 CYS H O 1 ATOM 5181 C CB . CYS C 3 208 ? 5.181 -3.243 28.769 1.00 99.94 ? 208 CYS H CB 1 ATOM 5182 S SG . CYS C 3 208 ? 5.066 -4.832 29.651 1.00 99.94 ? 208 CYS H SG 1 ATOM 5183 N N . ASN C 3 209 ? 2.775 -1.652 30.254 1.00 54.06 ? 209 ASN H N 1 ATOM 5184 C CA . ASN C 3 209 ? 1.589 -1.633 31.059 1.00 54.06 ? 209 ASN H CA 1 ATOM 5185 C C . ASN C 3 209 ? 0.478 -2.478 30.419 1.00 54.06 ? 209 ASN H C 1 ATOM 5186 O O . ASN C 3 209 ? 0.266 -2.509 29.228 1.00 54.06 ? 209 ASN H O 1 ATOM 5187 C CB . ASN C 3 209 ? 1.169 -0.185 31.139 1.00 79.79 ? 209 ASN H CB 1 ATOM 5188 C CG . ASN C 3 209 ? 2.130 0.652 31.969 1.00 79.79 ? 209 ASN H CG 1 ATOM 5189 O OD1 . ASN C 3 209 ? 2.095 0.688 33.219 1.00 79.79 ? 209 ASN H OD1 1 ATOM 5190 N ND2 . ASN C 3 209 ? 3.066 1.267 31.265 1.00 79.79 ? 209 ASN H ND2 1 ATOM 5191 N N . VAL C 3 210 ? -0.153 -3.277 31.240 1.00 72.87 ? 210 VAL H N 1 ATOM 5192 C CA . VAL C 3 210 ? -1.228 -4.097 30.781 1.00 72.87 ? 210 VAL H CA 1 ATOM 5193 C C . VAL C 3 210 ? -2.407 -3.660 31.606 1.00 72.87 ? 210 VAL H C 1 ATOM 5194 O O . VAL C 3 210 ? -2.272 -3.517 32.832 1.00 72.87 ? 210 VAL H O 1 ATOM 5195 C CB . VAL C 3 210 ? -0.920 -5.577 30.963 1.00 78.21 ? 210 VAL H CB 1 ATOM 5196 C CG1 . VAL C 3 210 ? -2.046 -6.389 30.481 1.00 78.21 ? 210 VAL H CG1 1 ATOM 5197 C CG2 . VAL C 3 210 ? 0.334 -5.921 30.226 1.00 78.21 ? 210 VAL H CG2 1 ATOM 5198 N N . ASN C 3 211 ? -3.523 -3.374 30.914 1.00 66.87 ? 211 ASN H N 1 ATOM 5199 C CA . ASN C 3 211 ? -4.800 -2.940 31.516 1.00 66.87 ? 211 ASN H CA 1 ATOM 5200 C C . ASN C 3 211 ? -5.880 -3.893 31.185 1.00 66.87 ? 211 ASN H C 1 ATOM 5201 O O . ASN C 3 211 ? -6.005 -4.213 30.068 1.00 66.87 ? 211 ASN H O 1 ATOM 5202 C CB . ASN C 3 211 ? -5.232 -1.587 30.997 1.00 113.35 ? 211 ASN H CB 1 ATOM 5203 C CG . ASN C 3 211 ? -6.440 -1.087 31.710 1.00 113.35 ? 211 ASN H CG 1 ATOM 5204 O OD1 . ASN C 3 211 ? -7.524 -1.055 31.151 1.00 113.35 ? 211 ASN H OD1 1 ATOM 5205 N ND2 . ASN C 3 211 ? -6.269 -0.688 32.950 1.00 113.35 ? 211 ASN H ND2 1 ATOM 5206 N N . HIS C 3 212 ? -6.660 -4.378 32.117 1.00 119.96 ? 212 HIS H N 1 ATOM 5207 C CA . HIS C 3 212 ? -7.669 -5.304 31.644 1.00 119.96 ? 212 HIS H CA 1 ATOM 5208 C C . HIS C 3 212 ? -8.985 -4.962 32.372 1.00 119.96 ? 212 HIS H C 1 ATOM 5209 O O . HIS C 3 212 ? -9.084 -5.238 33.574 1.00 119.96 ? 212 HIS H O 1 ATOM 5210 C CB . HIS C 3 212 ? -7.181 -6.699 32.044 1.00 82.69 ? 212 HIS H CB 1 ATOM 5211 C CG . HIS C 3 212 ? -7.970 -7.840 31.482 1.00 82.69 ? 212 HIS H CG 1 ATOM 5212 N ND1 . HIS C 3 212 ? -9.316 -8.013 31.734 1.00 82.69 ? 212 HIS H ND1 1 ATOM 5213 C CD2 . HIS C 3 212 ? -7.561 -8.980 30.877 1.00 82.69 ? 212 HIS H CD2 1 ATOM 5214 C CE1 . HIS C 3 212 ? -9.705 -9.201 31.303 1.00 82.69 ? 212 HIS H CE1 1 ATOM 5215 N NE2 . HIS C 3 212 ? -8.656 -9.811 30.784 1.00 82.69 ? 212 HIS H NE2 1 ATOM 5216 N N . LYS C 3 213 ? -9.963 -4.335 31.681 1.00 78.82 ? 213 LYS H N 1 ATOM 5217 C CA . LYS C 3 213 ? -11.284 -4.012 32.272 1.00 78.82 ? 213 LYS H CA 1 ATOM 5218 C C . LYS C 3 213 ? -12.125 -5.041 32.983 1.00 78.82 ? 213 LYS H C 1 ATOM 5219 O O . LYS C 3 213 ? -12.603 -4.796 34.063 1.00 78.82 ? 213 LYS H O 1 ATOM 5220 C CB . LYS C 3 213 ? -12.135 -3.181 31.343 1.00 63.96 ? 213 LYS H CB 1 ATOM 5221 C CG . LYS C 3 213 ? -11.709 -1.688 31.405 1.00 63.96 ? 213 LYS H CG 1 ATOM 5222 C CD . LYS C 3 213 ? -11.854 -1.141 32.849 1.00 63.96 ? 213 LYS H CD 1 ATOM 5223 C CE . LYS C 3 213 ? -13.270 -1.370 33.403 1.00 63.96 ? 213 LYS H CE 1 ATOM 5224 N NZ . LYS C 3 213 ? -14.309 -0.429 32.826 1.00 63.96 ? 213 LYS H NZ 1 ATOM 5225 N N . PRO C 3 214 ? -12.339 -6.200 32.361 1.00 120.11 ? 214 PRO H N 1 ATOM 5226 C CA . PRO C 3 214 ? -13.112 -7.380 32.818 1.00 120.11 ? 214 PRO H CA 1 ATOM 5227 C C . PRO C 3 214 ? -12.556 -7.964 34.144 1.00 120.11 ? 214 PRO H C 1 ATOM 5228 O O . PRO C 3 214 ? -13.290 -8.240 35.107 1.00 120.11 ? 214 PRO H O 1 ATOM 5229 C CB . PRO C 3 214 ? -12.946 -8.345 31.656 1.00 70.88 ? 214 PRO H CB 1 ATOM 5230 C CG . PRO C 3 214 ? -12.699 -7.379 30.406 1.00 70.88 ? 214 PRO H CG 1 ATOM 5231 C CD . PRO C 3 214 ? -11.777 -6.388 31.008 1.00 70.88 ? 214 PRO H CD 1 ATOM 5232 N N . SER C 3 215 ? -11.245 -8.202 34.082 1.00 107.69 ? 215 SER H N 1 ATOM 5233 C CA . SER C 3 215 ? -10.271 -8.640 35.116 1.00 107.69 ? 215 SER H CA 1 ATOM 5234 C C . SER C 3 215 ? -10.296 -7.567 36.204 1.00 107.69 ? 215 SER H C 1 ATOM 5235 O O . SER C 3 215 ? -10.233 -7.822 37.415 1.00 107.69 ? 215 SER H O 1 ATOM 5236 C CB . SER C 3 215 ? -8.861 -8.795 34.540 1.00 136.22 ? 215 SER H CB 1 ATOM 5237 O OG . SER C 3 215 ? -8.802 -9.881 33.630 1.00 136.22 ? 215 SER H OG 1 ATOM 5238 N N . ASN C 3 216 ? -10.378 -6.344 35.692 1.00 78.25 ? 216 ASN H N 1 ATOM 5239 C CA . ASN C 3 216 ? -10.305 -5.128 36.440 1.00 78.25 ? 216 ASN H CA 1 ATOM 5240 C C . ASN C 3 216 ? -8.970 -5.033 37.150 1.00 78.25 ? 216 ASN H C 1 ATOM 5241 O O . ASN C 3 216 ? -8.875 -4.616 38.268 1.00 78.25 ? 216 ASN H O 1 ATOM 5242 C CB . ASN C 3 216 ? -11.479 -5.139 37.405 1.00 69.93 ? 216 ASN H CB 1 ATOM 5243 C CG . ASN C 3 216 ? -11.824 -3.795 37.907 1.00 69.93 ? 216 ASN H CG 1 ATOM 5244 O OD1 . ASN C 3 216 ? -11.633 -2.791 37.230 1.00 69.93 ? 216 ASN H OD1 1 ATOM 5245 N ND2 . ASN C 3 216 ? -12.365 -3.757 39.107 1.00 69.93 ? 216 ASN H ND2 1 ATOM 5246 N N . THR C 3 217 ? -7.907 -5.440 36.461 1.00 59.58 ? 217 THR H N 1 ATOM 5247 C CA . THR C 3 217 ? -6.620 -5.340 37.079 1.00 59.58 ? 217 THR H CA 1 ATOM 5248 C C . THR C 3 217 ? -5.638 -4.636 36.114 1.00 59.58 ? 217 THR H C 1 ATOM 5249 O O . THR C 3 217 ? -5.757 -4.694 34.914 1.00 59.58 ? 217 THR H O 1 ATOM 5250 C CB . THR C 3 217 ? -6.054 -6.700 37.245 1.00 59.01 ? 217 THR H CB 1 ATOM 5251 O OG1 . THR C 3 217 ? -5.695 -7.221 35.980 1.00 59.01 ? 217 THR H OG1 1 ATOM 5252 C CG2 . THR C 3 217 ? -7.124 -7.619 37.748 1.00 59.01 ? 217 THR H CG2 1 ATOM 5253 N N . LYS C 3 218 ? -4.693 -3.911 36.672 1.00 62.69 ? 218 LYS H N 1 ATOM 5254 C CA . LYS C 3 218 ? -3.636 -3.278 35.910 1.00 62.69 ? 218 LYS H CA 1 ATOM 5255 C C . LYS C 3 218 ? -2.275 -3.599 36.429 1.00 62.69 ? 218 LYS H C 1 ATOM 5256 O O . LYS C 3 218 ? -2.013 -3.444 37.625 1.00 62.69 ? 218 LYS H O 1 ATOM 5257 C CB . LYS C 3 218 ? -3.764 -1.770 35.884 1.00 101.99 ? 218 LYS H CB 1 ATOM 5258 C CG . LYS C 3 218 ? -2.643 -1.174 35.080 1.00 101.99 ? 218 LYS H CG 1 ATOM 5259 C CD . LYS C 3 218 ? -2.692 0.327 35.005 1.00 101.99 ? 218 LYS H CD 1 ATOM 5260 C CE . LYS C 3 218 ? -1.516 0.826 34.184 1.00 101.99 ? 218 LYS H CE 1 ATOM 5261 N NZ . LYS C 3 218 ? -0.271 0.748 35.085 1.00 101.99 ? 218 LYS H NZ 1 ATOM 5262 N N . VAL C 3 219 ? -1.393 -4.024 35.523 1.00 59.24 ? 219 VAL H N 1 ATOM 5263 C CA . VAL C 3 219 ? 0.030 -4.351 35.779 1.00 59.24 ? 219 VAL H CA 1 ATOM 5264 C C . VAL C 3 219 ? 1.015 -3.633 34.990 1.00 59.24 ? 219 VAL H C 1 ATOM 5265 O O . VAL C 3 219 ? 0.883 -3.640 33.808 1.00 59.24 ? 219 VAL H O 1 ATOM 5266 C CB . VAL C 3 219 ? 0.412 -5.868 35.611 1.00 57.15 ? 219 VAL H CB 1 ATOM 5267 C CG1 . VAL C 3 219 ? 1.869 -6.030 35.846 1.00 57.15 ? 219 VAL H CG1 1 ATOM 5268 C CG2 . VAL C 3 219 ? -0.208 -6.701 36.799 1.00 57.15 ? 219 VAL H CG2 1 ATOM 5269 N N . ASP C 3 220 ? 2.026 -3.052 35.610 1.00 78.41 ? 220 ASP H N 1 ATOM 5270 C CA . ASP C 3 220 ? 3.029 -2.460 34.791 1.00 78.41 ? 220 ASP H CA 1 ATOM 5271 C C . ASP C 3 220 ? 4.231 -3.274 35.254 1.00 78.41 ? 220 ASP H C 1 ATOM 5272 O O . ASP C 3 220 ? 4.391 -3.510 36.443 1.00 78.41 ? 220 ASP H O 1 ATOM 5273 C CB . ASP C 3 220 ? 3.171 -0.948 35.053 1.00 157.47 ? 220 ASP H CB 1 ATOM 5274 C CG . ASP C 3 220 ? 3.670 -0.627 36.434 1.00 157.47 ? 220 ASP H CG 1 ATOM 5275 O OD1 . ASP C 3 220 ? 4.739 0.006 36.543 1.00 157.47 ? 220 ASP H OD1 1 ATOM 5276 O OD2 . ASP C 3 220 ? 2.995 -0.989 37.416 1.00 157.47 ? 220 ASP H OD2 1 ATOM 5277 N N . LYS C 3 221 ? 5.051 -3.728 34.289 1.00 48.41 ? 221 LYS H N 1 ATOM 5278 C CA . LYS C 3 221 ? 6.257 -4.515 34.542 1.00 48.41 ? 221 LYS H CA 1 ATOM 5279 C C . LYS C 3 221 ? 7.371 -4.054 33.612 1.00 48.41 ? 221 LYS H C 1 ATOM 5280 O O . LYS C 3 221 ? 7.188 -3.865 32.443 1.00 48.41 ? 221 LYS H O 1 ATOM 5281 C CB . LYS C 3 221 ? 5.991 -5.984 34.346 1.00 79.86 ? 221 LYS H CB 1 ATOM 5282 C CG . LYS C 3 221 ? 7.106 -6.779 34.817 1.00 79.86 ? 221 LYS H CG 1 ATOM 5283 C CD . LYS C 3 221 ? 6.825 -8.198 34.624 1.00 79.86 ? 221 LYS H CD 1 ATOM 5284 C CE . LYS C 3 221 ? 7.934 -8.956 35.286 1.00 79.86 ? 221 LYS H CE 1 ATOM 5285 N NZ . LYS C 3 221 ? 9.203 -8.605 34.662 1.00 79.86 ? 221 LYS H NZ 1 ATOM 5286 N N . LYS C 3 222 ? 8.561 -3.980 34.163 1.00 69.23 ? 222 LYS H N 1 ATOM 5287 C CA . LYS C 3 222 ? 9.748 -3.489 33.480 1.00 69.23 ? 222 LYS H CA 1 ATOM 5288 C C . LYS C 3 222 ? 10.549 -4.690 33.024 1.00 69.23 ? 222 LYS H C 1 ATOM 5289 O O . LYS C 3 222 ? 10.619 -5.709 33.680 1.00 69.23 ? 222 LYS H O 1 ATOM 5290 C CB . LYS C 3 222 ? 10.609 -2.607 34.390 1.00 123.98 ? 222 LYS H CB 1 ATOM 5291 C CG . LYS C 3 222 ? 11.843 -2.101 33.668 1.00 123.98 ? 222 LYS H CG 1 ATOM 5292 C CD . LYS C 3 222 ? 12.664 -1.010 34.405 1.00 123.98 ? 222 LYS H CD 1 ATOM 5293 C CE . LYS C 3 222 ? 13.431 -1.503 35.609 1.00 123.98 ? 222 LYS H CE 1 ATOM 5294 N NZ . LYS C 3 222 ? 14.434 -2.503 35.149 1.00 123.98 ? 222 LYS H NZ 1 ATOM 5295 N N . VAL C 3 223 ? 11.095 -4.593 31.833 1.00 79.04 ? 223 VAL H N 1 ATOM 5296 C CA . VAL C 3 223 ? 11.796 -5.708 31.275 1.00 79.04 ? 223 VAL H CA 1 ATOM 5297 C C . VAL C 3 223 ? 13.243 -5.303 31.282 1.00 79.04 ? 223 VAL H C 1 ATOM 5298 O O . VAL C 3 223 ? 13.614 -4.263 30.778 1.00 79.04 ? 223 VAL H O 1 ATOM 5299 C CB . VAL C 3 223 ? 11.314 -5.899 29.864 1.00 49.78 ? 223 VAL H CB 1 ATOM 5300 C CG1 . VAL C 3 223 ? 11.992 -7.040 29.209 1.00 49.78 ? 223 VAL H CG1 1 ATOM 5301 C CG2 . VAL C 3 223 ? 9.887 -6.125 29.865 1.00 49.78 ? 223 VAL H CG2 1 ATOM 5302 N N . GLU C 3 224 ? 14.030 -6.106 31.975 1.00 92.00 ? 224 GLU H N 1 ATOM 5303 C CA . GLU C 3 224 ? 15.447 -5.867 32.156 1.00 92.00 ? 224 GLU H CA 1 ATOM 5304 C C . GLU C 3 224 ? 16.317 -6.897 31.384 1.00 92.00 ? 224 GLU H C 1 ATOM 5305 O O . GLU C 3 224 ? 16.157 -8.121 31.558 1.00 92.00 ? 224 GLU H O 1 ATOM 5306 C CB . GLU C 3 224 ? 15.720 -5.819 33.692 1.00 112.54 ? 224 GLU H CB 1 ATOM 5307 C CG . GLU C 3 224 ? 17.114 -5.344 34.170 1.00 112.54 ? 224 GLU H CG 1 ATOM 5308 C CD . GLU C 3 224 ? 17.059 -4.631 35.541 1.00 112.54 ? 224 GLU H CD 1 ATOM 5309 O OE1 . GLU C 3 224 ? 17.000 -5.335 36.572 1.00 112.54 ? 224 GLU H OE1 1 ATOM 5310 O OE2 . GLU C 3 224 ? 17.062 -3.373 35.576 1.00 112.54 ? 224 GLU H OE2 1 ATOM 5311 N N . PRO C 3 225 ? 17.160 -6.427 30.451 1.00 88.25 ? 225 PRO H N 1 ATOM 5312 C CA . PRO C 3 225 ? 18.027 -7.320 29.682 1.00 88.25 ? 225 PRO H CA 1 ATOM 5313 C C . PRO C 3 225 ? 18.871 -8.320 30.488 1.00 88.25 ? 225 PRO H C 1 ATOM 5314 O O . PRO C 3 225 ? 19.410 -9.274 29.919 1.00 88.25 ? 225 PRO H O 1 ATOM 5315 C CB . PRO C 3 225 ? 18.885 -6.344 28.886 1.00 61.56 ? 225 PRO H CB 1 ATOM 5316 C CG . PRO C 3 225 ? 18.834 -5.063 29.677 1.00 61.56 ? 225 PRO H CG 1 ATOM 5317 C CD . PRO C 3 225 ? 17.402 -5.023 30.078 1.00 61.56 ? 225 PRO H CD 1 ATOM 5318 N N . SER D 4 2 ? -22.935 -31.373 -1.695 1.00 142.66 ? 3 SER L N 1 ATOM 5319 C CA . SER D 4 2 ? -23.567 -30.412 -0.758 1.00 142.66 ? 3 SER L CA 1 ATOM 5320 C C . SER D 4 2 ? -22.659 -29.222 -0.440 1.00 142.66 ? 3 SER L C 1 ATOM 5321 O O . SER D 4 2 ? -22.983 -28.449 0.464 1.00 142.66 ? 3 SER L O 1 ATOM 5322 C CB . SER D 4 2 ? -23.937 -31.115 0.561 1.00 78.88 ? 3 SER L CB 1 ATOM 5323 O OG . SER D 4 2 ? -22.793 -31.308 1.416 1.00 78.88 ? 3 SER L OG 1 ATOM 5324 N N . VAL D 4 3 ? -21.522 -29.091 -1.136 1.00 120.95 ? 4 VAL L N 1 ATOM 5325 C CA . VAL D 4 3 ? -20.601 -27.966 -0.891 1.00 120.95 ? 4 VAL L CA 1 ATOM 5326 C C . VAL D 4 3 ? -19.949 -27.305 -2.132 1.00 120.95 ? 4 VAL L C 1 ATOM 5327 O O . VAL D 4 3 ? -19.601 -27.991 -3.082 1.00 120.95 ? 4 VAL L O 1 ATOM 5328 C CB . VAL D 4 3 ? -19.479 -28.382 0.127 1.00 93.99 ? 4 VAL L CB 1 ATOM 5329 C CG1 . VAL D 4 3 ? -18.597 -29.479 -0.475 1.00 93.99 ? 4 VAL L CG1 1 ATOM 5330 C CG2 . VAL D 4 3 ? -18.658 -27.143 0.597 1.00 93.99 ? 4 VAL L CG2 1 ATOM 5331 N N . LEU D 4 4 ? -19.833 -25.973 -2.126 1.00 78.18 ? 5 LEU L N 1 ATOM 5332 C CA . LEU D 4 4 ? -19.189 -25.245 -3.200 1.00 78.18 ? 5 LEU L CA 1 ATOM 5333 C C . LEU D 4 4 ? -17.675 -25.086 -3.046 1.00 78.18 ? 5 LEU L C 1 ATOM 5334 O O . LEU D 4 4 ? -17.218 -24.972 -1.918 1.00 78.18 ? 5 LEU L O 1 ATOM 5335 C CB . LEU D 4 4 ? -19.791 -23.865 -3.335 1.00 66.58 ? 5 LEU L CB 1 ATOM 5336 C CG . LEU D 4 4 ? -21.268 -23.848 -3.640 1.00 66.58 ? 5 LEU L CG 1 ATOM 5337 C CD1 . LEU D 4 4 ? -21.744 -22.429 -3.752 1.00 66.58 ? 5 LEU L CD1 1 ATOM 5338 C CD2 . LEU D 4 4 ? -21.496 -24.554 -4.909 1.00 66.58 ? 5 LEU L CD2 1 ATOM 5339 N N . THR D 4 5 ? -16.874 -25.007 -4.130 1.00 81.04 ? 6 THR L N 1 ATOM 5340 C CA . THR D 4 5 ? -15.416 -24.815 -3.905 1.00 81.04 ? 6 THR L CA 1 ATOM 5341 C C . THR D 4 5 ? -14.959 -23.649 -4.738 1.00 81.04 ? 6 THR L C 1 ATOM 5342 O O . THR D 4 5 ? -15.370 -23.487 -5.851 1.00 81.04 ? 6 THR L O 1 ATOM 5343 C CB . THR D 4 5 ? -14.525 -26.013 -4.411 1.00 70.59 ? 6 THR L CB 1 ATOM 5344 O OG1 . THR D 4 5 ? -14.698 -26.181 -5.806 1.00 70.59 ? 6 THR L OG1 1 ATOM 5345 C CG2 . THR D 4 5 ? -14.915 -27.335 -3.735 1.00 70.59 ? 6 THR L CG2 1 ATOM 5346 N N . GLN D 4 6 ? -14.093 -22.846 -4.166 1.00 66.52 ? 7 GLN L N 1 ATOM 5347 C CA . GLN D 4 6 ? -13.484 -21.702 -4.813 1.00 66.52 ? 7 GLN L CA 1 ATOM 5348 C C . GLN D 4 6 ? -11.995 -21.575 -4.438 1.00 66.52 ? 7 GLN L C 1 ATOM 5349 O O . GLN D 4 6 ? -11.562 -22.115 -3.448 1.00 66.52 ? 7 GLN L O 1 ATOM 5350 C CB . GLN D 4 6 ? -14.261 -20.450 -4.595 1.00 66.12 ? 7 GLN L CB 1 ATOM 5351 C CG . GLN D 4 6 ? -14.435 -20.032 -3.235 1.00 66.12 ? 7 GLN L CG 1 ATOM 5352 C CD . GLN D 4 6 ? -15.075 -18.643 -3.174 1.00 66.12 ? 7 GLN L CD 1 ATOM 5353 O OE1 . GLN D 4 6 ? -16.290 -18.485 -3.365 1.00 66.12 ? 7 GLN L OE1 1 ATOM 5354 N NE2 . GLN D 4 6 ? -14.263 -17.626 -2.926 1.00 66.12 ? 7 GLN L NE2 1 ATOM 5355 N N . PRO D 4 7 ? -11.175 -20.865 -5.203 1.00 70.56 ? 8 PRO L N 1 ATOM 5356 C CA . PRO D 4 7 ? -9.875 -20.998 -4.573 1.00 70.56 ? 8 PRO L CA 1 ATOM 5357 C C . PRO D 4 7 ? -9.594 -20.310 -3.204 1.00 70.56 ? 8 PRO L C 1 ATOM 5358 O O . PRO D 4 7 ? -10.288 -19.363 -2.803 1.00 70.56 ? 8 PRO L O 1 ATOM 5359 C CB . PRO D 4 7 ? -9.019 -20.487 -5.706 1.00 91.25 ? 8 PRO L CB 1 ATOM 5360 C CG . PRO D 4 7 ? -9.639 -19.129 -5.854 1.00 91.25 ? 8 PRO L CG 1 ATOM 5361 C CD . PRO D 4 7 ? -11.159 -19.634 -6.016 1.00 91.25 ? 8 PRO L CD 1 ATOM 5362 N N . PRO D 4 8 ? -8.612 -20.851 -2.435 1.00 68.28 ? 9 PRO L N 1 ATOM 5363 C CA . PRO D 4 8 ? -8.279 -20.282 -1.131 1.00 68.28 ? 9 PRO L CA 1 ATOM 5364 C C . PRO D 4 8 ? -7.399 -19.085 -1.361 1.00 68.28 ? 9 PRO L C 1 ATOM 5365 O O . PRO D 4 8 ? -7.370 -18.258 -0.476 1.00 68.28 ? 9 PRO L O 1 ATOM 5366 C CB . PRO D 4 8 ? -7.642 -21.440 -0.360 1.00 86.84 ? 9 PRO L CB 1 ATOM 5367 C CG . PRO D 4 8 ? -8.001 -22.684 -1.170 1.00 86.84 ? 9 PRO L CG 1 ATOM 5368 C CD . PRO D 4 8 ? -7.963 -22.158 -2.596 1.00 86.84 ? 9 PRO L CD 1 ATOM 5369 N N . SER D 4 9 ? -6.602 -18.991 -2.443 1.00 51.37 ? 10 SER L N 1 ATOM 5370 C CA . SER D 4 9 ? -5.947 -17.672 -2.650 1.00 51.37 ? 10 SER L CA 1 ATOM 5371 C C . SER D 4 9 ? -5.632 -17.151 -4.056 1.00 51.37 ? 10 SER L C 1 ATOM 5372 O O . SER D 4 9 ? -5.331 -17.853 -5.046 1.00 51.37 ? 10 SER L O 1 ATOM 5373 C CB . SER D 4 9 ? -4.657 -17.504 -1.791 1.00 70.34 ? 10 SER L CB 1 ATOM 5374 O OG . SER D 4 9 ? -3.582 -18.315 -2.207 1.00 70.34 ? 10 SER L OG 1 ATOM 5375 N N . VAL D 4 10 ? -5.683 -15.839 -4.083 1.00 65.01 ? 11 VAL L N 1 ATOM 5376 C CA . VAL D 4 10 ? -5.459 -14.992 -5.241 1.00 65.01 ? 11 VAL L CA 1 ATOM 5377 C C . VAL D 4 10 ? -4.678 -13.666 -5.154 1.00 65.01 ? 11 VAL L C 1 ATOM 5378 O O . VAL D 4 10 ? -4.791 -12.989 -4.118 1.00 65.01 ? 11 VAL L O 1 ATOM 5379 C CB . VAL D 4 10 ? -6.714 -14.889 -6.074 1.00 63.47 ? 11 VAL L CB 1 ATOM 5380 C CG1 . VAL D 4 10 ? -6.484 -13.988 -7.219 1.00 63.47 ? 11 VAL L CG1 1 ATOM 5381 C CG2 . VAL D 4 10 ? -7.034 -16.263 -6.601 1.00 63.47 ? 11 VAL L CG2 1 ATOM 5382 N N . SER D 4 11 ? -3.831 -13.326 -6.128 1.00 85.90 ? 12 SER L N 1 ATOM 5383 C CA . SER D 4 11 ? -3.128 -12.030 -6.065 1.00 85.90 ? 12 SER L CA 1 ATOM 5384 C C . SER D 4 11 ? -2.938 -11.189 -7.366 1.00 85.90 ? 12 SER L C 1 ATOM 5385 O O . SER D 4 11 ? -2.963 -11.733 -8.437 1.00 85.90 ? 12 SER L O 1 ATOM 5386 C CB . SER D 4 11 ? -1.763 -12.323 -5.537 1.00 83.13 ? 12 SER L CB 1 ATOM 5387 O OG . SER D 4 11 ? -1.089 -13.060 -6.536 1.00 83.13 ? 12 SER L OG 1 ATOM 5388 N N . ALA D 4 12 ? -2.764 -9.867 -7.275 1.00 58.20 ? 13 ALA L N 1 ATOM 5389 C CA . ALA D 4 12 ? -2.535 -9.004 -8.463 1.00 58.20 ? 13 ALA L CA 1 ATOM 5390 C C . ALA D 4 12 ? -1.901 -7.620 -8.313 1.00 58.20 ? 13 ALA L C 1 ATOM 5391 O O . ALA D 4 12 ? -1.790 -7.094 -7.201 1.00 58.20 ? 13 ALA L O 1 ATOM 5392 C CB . ALA D 4 12 ? -3.766 -8.858 -9.263 1.00 55.25 ? 13 ALA L CB 1 ATOM 5393 N N . ALA D 4 13 ? -1.363 -7.105 -9.417 1.00 66.44 ? 14 ALA L N 1 ATOM 5394 C CA . ALA D 4 13 ? -0.803 -5.730 -9.502 1.00 66.44 ? 14 ALA L CA 1 ATOM 5395 C C . ALA D 4 13 ? -1.908 -4.684 -9.433 1.00 66.44 ? 14 ALA L C 1 ATOM 5396 O O . ALA D 4 13 ? -3.016 -5.025 -9.708 1.00 66.44 ? 14 ALA L O 1 ATOM 5397 C CB . ALA D 4 13 ? -0.010 -5.567 -10.814 1.00 116.70 ? 14 ALA L CB 1 ATOM 5398 N N . PRO D 4 14 ? -1.619 -3.424 -9.095 1.00 76.93 ? 15 PRO L N 1 ATOM 5399 C CA . PRO D 4 14 ? -2.566 -2.319 -9.004 1.00 76.93 ? 15 PRO L CA 1 ATOM 5400 C C . PRO D 4 14 ? -3.220 -1.804 -10.324 1.00 76.93 ? 15 PRO L C 1 ATOM 5401 O O . PRO D 4 14 ? -4.097 -0.918 -10.315 1.00 76.93 ? 15 PRO L O 1 ATOM 5402 C CB . PRO D 4 14 ? -1.776 -1.245 -8.288 1.00 68.27 ? 15 PRO L CB 1 ATOM 5403 C CG . PRO D 4 14 ? -1.034 -1.989 -7.409 1.00 68.27 ? 15 PRO L CG 1 ATOM 5404 C CD . PRO D 4 14 ? -0.509 -3.157 -8.203 1.00 68.27 ? 15 PRO L CD 1 ATOM 5405 N N . GLY D 4 15 ? -2.749 -2.247 -11.474 1.00 64.87 ? 16 GLY L N 1 ATOM 5406 C CA . GLY D 4 15 ? -3.434 -1.896 -12.724 1.00 64.87 ? 16 GLY L CA 1 ATOM 5407 C C . GLY D 4 15 ? -4.417 -2.994 -13.211 1.00 64.87 ? 16 GLY L C 1 ATOM 5408 O O . GLY D 4 15 ? -5.515 -2.827 -13.723 1.00 64.87 ? 16 GLY L O 1 ATOM 5409 N N . GLN D 4 16 ? -3.904 -4.183 -12.992 1.00 74.53 ? 17 GLN L N 1 ATOM 5410 C CA . GLN D 4 16 ? -4.354 -5.489 -13.440 1.00 74.53 ? 17 GLN L CA 1 ATOM 5411 C C . GLN D 4 16 ? -5.659 -6.162 -13.170 1.00 74.53 ? 17 GLN L C 1 ATOM 5412 O O . GLN D 4 16 ? -6.246 -6.037 -12.115 1.00 74.53 ? 17 GLN L O 1 ATOM 5413 C CB . GLN D 4 16 ? -3.273 -6.517 -13.051 1.00 106.58 ? 17 GLN L CB 1 ATOM 5414 C CG . GLN D 4 16 ? -3.578 -7.978 -13.453 1.00 106.58 ? 17 GLN L CG 1 ATOM 5415 C CD . GLN D 4 16 ? -2.466 -8.908 -13.032 1.00 106.58 ? 17 GLN L CD 1 ATOM 5416 O OE1 . GLN D 4 16 ? -2.058 -8.855 -11.865 1.00 106.58 ? 17 GLN L OE1 1 ATOM 5417 N NE2 . GLN D 4 16 ? -1.984 -9.763 -13.938 1.00 106.58 ? 17 GLN L NE2 1 ATOM 5418 N N . LYS D 4 17 ? -6.153 -6.809 -14.201 1.00 64.35 ? 18 LYS L N 1 ATOM 5419 C CA . LYS D 4 17 ? -7.335 -7.628 -14.058 1.00 64.35 ? 18 LYS L CA 1 ATOM 5420 C C . LYS D 4 17 ? -7.079 -9.041 -13.463 1.00 64.35 ? 18 LYS L C 1 ATOM 5421 O O . LYS D 4 17 ? -6.054 -9.656 -13.696 1.00 64.35 ? 18 LYS L O 1 ATOM 5422 C CB . LYS D 4 17 ? -8.067 -7.821 -15.375 1.00 60.30 ? 18 LYS L CB 1 ATOM 5423 C CG . LYS D 4 17 ? -9.339 -8.721 -15.168 1.00 60.30 ? 18 LYS L CG 1 ATOM 5424 C CD . LYS D 4 17 ? -10.074 -8.917 -16.476 1.00 60.30 ? 18 LYS L CD 1 ATOM 5425 C CE . LYS D 4 17 ? -11.271 -9.761 -16.324 1.00 60.30 ? 18 LYS L CE 1 ATOM 5426 N NZ . LYS D 4 17 ? -11.755 -9.843 -17.666 1.00 60.30 ? 18 LYS L NZ 1 ATOM 5427 N N . VAL D 4 18 ? -8.023 -9.471 -12.631 1.00 57.90 ? 19 VAL L N 1 ATOM 5428 C CA . VAL D 4 18 ? -8.093 -10.744 -11.892 1.00 57.90 ? 19 VAL L CA 1 ATOM 5429 C C . VAL D 4 18 ? -9.421 -11.497 -11.742 1.00 57.90 ? 19 VAL L C 1 ATOM 5430 O O . VAL D 4 18 ? -10.403 -10.848 -11.500 1.00 57.90 ? 19 VAL L O 1 ATOM 5431 C CB . VAL D 4 18 ? -7.508 -10.577 -10.477 1.00 47.47 ? 19 VAL L CB 1 ATOM 5432 C CG1 . VAL D 4 18 ? -8.089 -9.401 -9.787 1.00 47.47 ? 19 VAL L CG1 1 ATOM 5433 C CG2 . VAL D 4 18 ? -7.889 -11.797 -9.668 1.00 47.47 ? 19 VAL L CG2 1 ATOM 5434 N N . THR D 4 19 ? -9.486 -12.821 -11.832 1.00 68.50 ? 20 THR L N 1 ATOM 5435 C CA . THR D 4 19 ? -10.797 -13.417 -11.592 1.00 68.50 ? 20 THR L CA 1 ATOM 5436 C C . THR D 4 19 ? -10.829 -14.565 -10.579 1.00 68.50 ? 20 THR L C 1 ATOM 5437 O O . THR D 4 19 ? -9.903 -15.356 -10.525 1.00 68.50 ? 20 THR L O 1 ATOM 5438 C CB . THR D 4 19 ? -11.399 -14.008 -12.877 1.00 77.25 ? 20 THR L CB 1 ATOM 5439 O OG1 . THR D 4 19 ? -10.668 -15.164 -13.273 1.00 77.25 ? 20 THR L OG1 1 ATOM 5440 C CG2 . THR D 4 19 ? -11.328 -13.008 -13.972 1.00 77.25 ? 20 THR L CG2 1 ATOM 5441 N N . ILE D 4 20 ? -11.966 -14.709 -9.887 1.00 78.15 ? 21 ILE L N 1 ATOM 5442 C CA . ILE D 4 20 ? -12.211 -15.745 -8.889 1.00 78.15 ? 21 ILE L CA 1 ATOM 5443 C C . ILE D 4 20 ? -13.347 -16.609 -9.234 1.00 78.15 ? 21 ILE L C 1 ATOM 5444 O O . ILE D 4 20 ? -14.458 -16.180 -9.274 1.00 78.15 ? 21 ILE L O 1 ATOM 5445 C CB . ILE D 4 20 ? -12.356 -15.227 -7.430 1.00 76.72 ? 21 ILE L CB 1 ATOM 5446 C CG1 . ILE D 4 20 ? -11.070 -14.520 -7.041 1.00 76.72 ? 21 ILE L CG1 1 ATOM 5447 C CG2 . ILE D 4 20 ? -12.909 -16.272 -6.577 1.00 76.72 ? 21 ILE L CG2 1 ATOM 5448 C CD1 . ILE D 4 20 ? -11.044 -13.770 -5.800 1.00 76.72 ? 21 ILE L CD1 1 ATOM 5449 N N . SER D 4 21 ? -13.049 -17.888 -9.367 1.00 77.36 ? 22 SER L N 1 ATOM 5450 C CA . SER D 4 21 ? -14.025 -18.817 -9.843 1.00 77.36 ? 22 SER L CA 1 ATOM 5451 C C . SER D 4 21 ? -14.465 -19.882 -8.893 1.00 77.36 ? 22 SER L C 1 ATOM 5452 O O . SER D 4 21 ? -13.672 -20.638 -8.397 1.00 77.36 ? 22 SER L O 1 ATOM 5453 C CB . SER D 4 21 ? -13.363 -19.454 -11.031 1.00 111.88 ? 22 SER L CB 1 ATOM 5454 O OG . SER D 4 21 ? -12.009 -19.716 -10.672 1.00 111.88 ? 22 SER L OG 1 ATOM 5455 N N . CYS D 4 22 ? -15.783 -20.002 -8.782 1.00 59.33 ? 23 CYS L N 1 ATOM 5456 C CA . CYS D 4 22 ? -16.448 -20.945 -7.872 1.00 59.33 ? 23 CYS L CA 1 ATOM 5457 C C . CYS D 4 22 ? -17.277 -21.981 -8.612 1.00 59.33 ? 23 CYS L C 1 ATOM 5458 O O . CYS D 4 22 ? -18.082 -21.600 -9.412 1.00 59.33 ? 23 CYS L O 1 ATOM 5459 C CB . CYS D 4 22 ? -17.257 -20.113 -6.832 1.00 88.85 ? 23 CYS L CB 1 ATOM 5460 S SG . CYS D 4 22 ? -18.890 -20.597 -6.175 1.00 88.85 ? 23 CYS L SG 1 ATOM 5461 N N . SER D 4 23 ? -17.134 -23.267 -8.262 1.00 61.75 ? 24 SER L N 1 ATOM 5462 C CA . SER D 4 23 ? -17.814 -24.361 -8.946 1.00 61.75 ? 24 SER L CA 1 ATOM 5463 C C . SER D 4 23 ? -18.587 -25.268 -8.051 1.00 61.75 ? 24 SER L C 1 ATOM 5464 O O . SER D 4 23 ? -18.092 -25.699 -7.026 1.00 61.75 ? 24 SER L O 1 ATOM 5465 C CB . SER D 4 23 ? -16.814 -25.268 -9.610 1.00 62.26 ? 24 SER L CB 1 ATOM 5466 O OG . SER D 4 23 ? -16.070 -24.562 -10.541 1.00 62.26 ? 24 SER L OG 1 ATOM 5467 N N . GLY D 4 24 ? -19.754 -25.673 -8.524 1.00 79.15 ? 25 GLY L N 1 ATOM 5468 C CA . GLY D 4 24 ? -20.588 -26.527 -7.725 1.00 79.15 ? 25 GLY L CA 1 ATOM 5469 C C . GLY D 4 24 ? -21.198 -27.640 -8.524 1.00 79.15 ? 25 GLY L C 1 ATOM 5470 O O . GLY D 4 24 ? -20.598 -28.198 -9.422 1.00 79.15 ? 25 GLY L O 1 ATOM 5471 N N . SER D 4 25 ? -22.449 -27.906 -8.199 1.00 82.22 ? 26 SER L N 1 ATOM 5472 C CA . SER D 4 25 ? -23.273 -28.975 -8.758 1.00 82.22 ? 26 SER L CA 1 ATOM 5473 C C . SER D 4 25 ? -24.670 -28.555 -9.279 1.00 82.22 ? 26 SER L C 1 ATOM 5474 O O . SER D 4 25 ? -25.345 -27.646 -8.751 1.00 82.22 ? 26 SER L O 1 ATOM 5475 C CB . SER D 4 25 ? -23.448 -30.096 -7.726 1.00 86.29 ? 26 SER L CB 1 ATOM 5476 O OG . SER D 4 25 ? -22.218 -30.662 -7.357 1.00 86.29 ? 26 SER L OG 1 ATOM 5477 N N . SER D 4 26 ? -25.140 -29.283 -10.283 1.00 97.88 ? 27 SER L N 1 ATOM 5478 C CA . SER D 4 26 ? -26.415 -28.939 -10.879 1.00 97.88 ? 27 SER L CA 1 ATOM 5479 C C . SER D 4 26 ? -27.411 -28.880 -9.729 1.00 97.88 ? 27 SER L C 1 ATOM 5480 O O . SER D 4 26 ? -28.374 -28.144 -9.821 1.00 97.88 ? 27 SER L O 1 ATOM 5481 C CB . SER D 4 26 ? -26.813 -29.993 -11.936 1.00 95.18 ? 27 SER L CB 1 ATOM 5482 O OG . SER D 4 26 ? -27.130 -31.242 -11.345 1.00 95.18 ? 27 SER L OG 1 ATOM 5483 N N . SER D 4 27 ? -27.216 -29.657 -8.673 1.00 85.16 ? 28 SER L N 1 ATOM 5484 C CA . SER D 4 27 ? -28.121 -29.561 -7.526 1.00 85.16 ? 28 SER L CA 1 ATOM 5485 C C . SER D 4 27 ? -28.176 -28.160 -6.846 1.00 85.16 ? 28 SER L C 1 ATOM 5486 O O . SER D 4 27 ? -29.233 -27.759 -6.336 1.00 85.16 ? 28 SER L O 1 ATOM 5487 C CB . SER D 4 27 ? -27.786 -30.643 -6.473 1.00 126.92 ? 28 SER L CB 1 ATOM 5488 O OG . SER D 4 27 ? -26.552 -30.398 -5.813 1.00 126.92 ? 28 SER L OG 1 ATOM 5489 N N . ASN D 4 28 ? -27.043 -27.468 -6.696 1.00 109.13 ? 29 ASN L N 1 ATOM 5490 C CA . ASN D 4 28 ? -27.094 -26.088 -6.188 1.00 109.13 ? 29 ASN L CA 1 ATOM 5491 C C . ASN D 4 28 ? -27.168 -25.029 -7.286 1.00 109.13 ? 29 ASN L C 1 ATOM 5492 O O . ASN D 4 28 ? -28.238 -24.503 -7.582 1.00 109.13 ? 29 ASN L O 1 ATOM 5493 C CB . ASN D 4 28 ? -25.917 -25.725 -5.297 1.00 105.26 ? 29 ASN L CB 1 ATOM 5494 C CG . ASN D 4 28 ? -24.596 -25.879 -5.993 1.00 105.26 ? 29 ASN L CG 1 ATOM 5495 O OD1 . ASN D 4 28 ? -24.253 -26.967 -6.428 1.00 105.26 ? 29 ASN L OD1 1 ATOM 5496 N ND2 . ASN D 4 28 ? -23.875 -24.780 -6.164 1.00 105.26 ? 29 ASN L ND2 1 ATOM 5497 N N . ILE D 4 29 ? -25.994 -24.731 -7.877 1.00 127.32 ? 30 ILE L N 1 ATOM 5498 C CA . ILE D 4 29 ? -25.819 -23.726 -8.941 1.00 127.32 ? 30 ILE L CA 1 ATOM 5499 C C . ILE D 4 29 ? -26.529 -23.804 -10.286 1.00 127.32 ? 30 ILE L C 1 ATOM 5500 O O . ILE D 4 29 ? -27.010 -22.789 -10.793 1.00 127.32 ? 30 ILE L O 1 ATOM 5501 C CB . ILE D 4 29 ? -24.361 -23.499 -9.302 1.00 41.08 ? 30 ILE L CB 1 ATOM 5502 C CG1 . ILE D 4 29 ? -23.537 -23.000 -8.148 1.00 41.08 ? 30 ILE L CG1 1 ATOM 5503 C CG2 . ILE D 4 29 ? -24.313 -22.452 -10.353 1.00 41.08 ? 30 ILE L CG2 1 ATOM 5504 C CD1 . ILE D 4 29 ? -24.032 -21.775 -7.674 1.00 41.08 ? 30 ILE L CD1 1 ATOM 5505 N N . GLY D 4 30 ? -26.585 -24.976 -10.903 1.00 72.27 ? 31 GLY L N 1 ATOM 5506 C CA . GLY D 4 30 ? -27.199 -24.959 -12.217 1.00 72.27 ? 31 GLY L CA 1 ATOM 5507 C C . GLY D 4 30 ? -28.570 -24.474 -12.006 1.00 72.27 ? 31 GLY L C 1 ATOM 5508 O O . GLY D 4 30 ? -28.919 -23.507 -12.616 1.00 72.27 ? 31 GLY L O 1 ATOM 5509 N N . LYS D 4 31 ? -29.279 -25.054 -11.061 1.00 93.99 ? 32 LYS L N 1 ATOM 5510 C CA . LYS D 4 31 ? -30.603 -24.602 -10.748 1.00 93.99 ? 32 LYS L CA 1 ATOM 5511 C C . LYS D 4 31 ? -30.909 -23.188 -10.251 1.00 93.99 ? 32 LYS L C 1 ATOM 5512 O O . LYS D 4 31 ? -31.872 -22.582 -10.662 1.00 93.99 ? 32 LYS L O 1 ATOM 5513 C CB . LYS D 4 31 ? -31.279 -25.542 -9.763 1.00 116.11 ? 32 LYS L CB 1 ATOM 5514 C CG . LYS D 4 31 ? -31.695 -26.927 -10.198 1.00 116.11 ? 32 LYS L CG 1 ATOM 5515 C CD . LYS D 4 31 ? -32.314 -27.543 -8.946 1.00 116.11 ? 32 LYS L CD 1 ATOM 5516 C CE . LYS D 4 31 ? -32.844 -28.952 -9.069 1.00 116.11 ? 32 LYS L CE 1 ATOM 5517 N NZ . LYS D 4 31 ? -34.313 -28.863 -9.328 1.00 116.11 ? 32 LYS L NZ 1 ATOM 5518 N N . ASN D 4 32 ? -30.068 -22.651 -9.383 1.00 74.75 ? 33 ASN L N 1 ATOM 5519 C CA . ASN D 4 32 ? -30.347 -21.384 -8.671 1.00 74.75 ? 33 ASN L CA 1 ATOM 5520 C C . ASN D 4 32 ? -29.446 -20.164 -8.813 1.00 74.75 ? 33 ASN L C 1 ATOM 5521 O O . ASN D 4 32 ? -28.331 -20.281 -9.279 1.00 74.75 ? 33 ASN L O 1 ATOM 5522 C CB . ASN D 4 32 ? -30.570 -21.737 -7.187 1.00 61.09 ? 33 ASN L CB 1 ATOM 5523 C CG . ASN D 4 32 ? -31.776 -22.724 -6.975 1.00 61.09 ? 33 ASN L CG 1 ATOM 5524 O OD1 . ASN D 4 32 ? -31.613 -23.842 -6.456 1.00 61.09 ? 33 ASN L OD1 1 ATOM 5525 N ND2 . ASN D 4 32 ? -32.988 -22.279 -7.335 1.00 61.09 ? 33 ASN L ND2 1 ATOM 5526 N N . TYR D 4 33 ? -29.912 -18.985 -8.425 1.00 80.91 ? 34 TYR L N 1 ATOM 5527 C CA . TYR D 4 33 ? -29.039 -17.844 -8.569 1.00 80.91 ? 34 TYR L CA 1 ATOM 5528 C C . TYR D 4 33 ? -27.848 -17.780 -7.658 1.00 80.91 ? 34 TYR L C 1 ATOM 5529 O O . TYR D 4 33 ? -27.871 -18.278 -6.541 1.00 80.91 ? 34 TYR L O 1 ATOM 5530 C CB . TYR D 4 33 ? -29.714 -16.486 -8.412 1.00 103.95 ? 34 TYR L CB 1 ATOM 5531 C CG . TYR D 4 33 ? -30.618 -15.973 -9.488 1.00 103.95 ? 34 TYR L CG 1 ATOM 5532 C CD1 . TYR D 4 33 ? -30.053 -15.499 -10.678 1.00 103.95 ? 34 TYR L CD1 1 ATOM 5533 C CD2 . TYR D 4 33 ? -31.958 -15.687 -9.252 1.00 103.95 ? 34 TYR L CD2 1 ATOM 5534 C CE1 . TYR D 4 33 ? -30.774 -14.752 -11.610 1.00 103.95 ? 34 TYR L CE1 1 ATOM 5535 C CE2 . TYR D 4 33 ? -32.711 -14.912 -10.194 1.00 103.95 ? 34 TYR L CE2 1 ATOM 5536 C CZ . TYR D 4 33 ? -32.100 -14.451 -11.377 1.00 103.95 ? 34 TYR L CZ 1 ATOM 5537 O OH . TYR D 4 33 ? -32.796 -13.696 -12.318 1.00 103.95 ? 34 TYR L OH 1 ATOM 5538 N N . VAL D 4 34 ? -26.800 -17.144 -8.203 1.00 65.53 ? 35 VAL L N 1 ATOM 5539 C CA . VAL D 4 34 ? -25.469 -16.900 -7.607 1.00 65.53 ? 35 VAL L CA 1 ATOM 5540 C C . VAL D 4 34 ? -25.333 -15.424 -7.309 1.00 65.53 ? 35 VAL L C 1 ATOM 5541 O O . VAL D 4 34 ? -25.497 -14.614 -8.186 1.00 65.53 ? 35 VAL L O 1 ATOM 5542 C CB . VAL D 4 34 ? -24.361 -17.243 -8.639 1.00 94.50 ? 35 VAL L CB 1 ATOM 5543 C CG1 . VAL D 4 34 ? -22.982 -17.008 -8.072 1.00 94.50 ? 35 VAL L CG1 1 ATOM 5544 C CG2 . VAL D 4 34 ? -24.471 -18.711 -9.025 1.00 94.50 ? 35 VAL L CG2 1 ATOM 5545 N N . SER D 4 35 ? -24.993 -15.073 -6.088 1.00 62.07 ? 36 SER L N 1 ATOM 5546 C CA . SER D 4 35 ? -24.830 -13.668 -5.796 1.00 62.07 ? 36 SER L CA 1 ATOM 5547 C C . SER D 4 35 ? -23.465 -13.723 -5.062 1.00 62.07 ? 36 SER L C 1 ATOM 5548 O O . SER D 4 35 ? -23.200 -14.760 -4.451 1.00 62.07 ? 36 SER L O 1 ATOM 5549 C CB . SER D 4 35 ? -25.969 -13.159 -4.933 1.00 31.10 ? 36 SER L CB 1 ATOM 5550 O OG . SER D 4 35 ? -25.897 -13.698 -3.646 1.00 31.10 ? 36 SER L OG 1 ATOM 5551 N N . TRP D 4 36 ? -22.677 -12.612 -5.015 1.00 53.25 ? 37 TRP L N 1 ATOM 5552 C CA . TRP D 4 36 ? -21.246 -12.563 -4.488 1.00 53.25 ? 37 TRP L CA 1 ATOM 5553 C C . TRP D 4 36 ? -21.076 -11.561 -3.255 1.00 53.25 ? 37 TRP L C 1 ATOM 5554 O O . TRP D 4 36 ? -21.806 -10.514 -3.206 1.00 53.25 ? 37 TRP L O 1 ATOM 5555 C CB . TRP D 4 36 ? -20.349 -12.044 -5.570 1.00 71.74 ? 37 TRP L CB 1 ATOM 5556 C CG . TRP D 4 36 ? -20.214 -12.954 -6.583 1.00 71.74 ? 37 TRP L CG 1 ATOM 5557 C CD1 . TRP D 4 36 ? -20.957 -12.960 -7.665 1.00 71.74 ? 37 TRP L CD1 1 ATOM 5558 C CD2 . TRP D 4 36 ? -19.234 -13.974 -6.736 1.00 71.74 ? 37 TRP L CD2 1 ATOM 5559 N NE1 . TRP D 4 36 ? -20.533 -13.908 -8.528 1.00 71.74 ? 37 TRP L NE1 1 ATOM 5560 C CE2 . TRP D 4 36 ? -19.461 -14.553 -7.986 1.00 71.74 ? 37 TRP L CE2 1 ATOM 5561 C CE3 . TRP D 4 36 ? -18.193 -14.464 -5.946 1.00 71.74 ? 37 TRP L CE3 1 ATOM 5562 C CZ2 . TRP D 4 36 ? -18.683 -15.602 -8.487 1.00 71.74 ? 37 TRP L CZ2 1 ATOM 5563 C CZ3 . TRP D 4 36 ? -17.424 -15.516 -6.433 1.00 71.74 ? 37 TRP L CZ3 1 ATOM 5564 C CH2 . TRP D 4 36 ? -17.670 -16.071 -7.687 1.00 71.74 ? 37 TRP L CH2 1 ATOM 5565 N N . TYR D 4 37 ? -20.276 -11.927 -2.212 1.00 51.97 ? 38 TYR L N 1 ATOM 5566 C CA . TYR D 4 37 ? -20.190 -11.018 -1.081 1.00 51.97 ? 38 TYR L CA 1 ATOM 5567 C C . TYR D 4 37 ? -18.766 -10.521 -0.830 1.00 51.97 ? 38 TYR L C 1 ATOM 5568 O O . TYR D 4 37 ? -17.873 -11.362 -0.766 1.00 51.97 ? 38 TYR L O 1 ATOM 5569 C CB . TYR D 4 37 ? -20.679 -11.818 0.059 1.00 55.29 ? 38 TYR L CB 1 ATOM 5570 C CG . TYR D 4 37 ? -22.082 -12.262 -0.190 1.00 55.29 ? 38 TYR L CG 1 ATOM 5571 C CD1 . TYR D 4 37 ? -23.171 -11.506 0.177 1.00 55.29 ? 38 TYR L CD1 1 ATOM 5572 C CD2 . TYR D 4 37 ? -22.316 -13.477 -0.764 1.00 55.29 ? 38 TYR L CD2 1 ATOM 5573 C CE1 . TYR D 4 37 ? -24.495 -11.969 -0.037 1.00 55.29 ? 38 TYR L CE1 1 ATOM 5574 C CE2 . TYR D 4 37 ? -23.597 -13.940 -0.969 1.00 55.29 ? 38 TYR L CE2 1 ATOM 5575 C CZ . TYR D 4 37 ? -24.681 -13.190 -0.609 1.00 55.29 ? 38 TYR L CZ 1 ATOM 5576 O OH . TYR D 4 37 ? -25.931 -13.687 -0.818 1.00 55.29 ? 38 TYR L OH 1 ATOM 5577 N N . GLN D 4 38 ? -18.559 -9.197 -0.609 1.00 70.23 ? 39 GLN L N 1 ATOM 5578 C CA . GLN D 4 38 ? -17.195 -8.636 -0.433 1.00 70.23 ? 39 GLN L CA 1 ATOM 5579 C C . GLN D 4 38 ? -16.863 -8.409 1.022 1.00 70.23 ? 39 GLN L C 1 ATOM 5580 O O . GLN D 4 38 ? -17.483 -7.628 1.660 1.00 70.23 ? 39 GLN L O 1 ATOM 5581 C CB . GLN D 4 38 ? -17.053 -7.275 -1.165 1.00 48.55 ? 39 GLN L CB 1 ATOM 5582 C CG . GLN D 4 38 ? -15.703 -6.545 -1.128 1.00 48.55 ? 39 GLN L CG 1 ATOM 5583 C CD . GLN D 4 38 ? -15.609 -5.191 -1.873 1.00 48.55 ? 39 GLN L CD 1 ATOM 5584 O OE1 . GLN D 4 38 ? -16.300 -4.246 -1.597 1.00 48.55 ? 39 GLN L OE1 1 ATOM 5585 N NE2 . GLN D 4 38 ? -14.803 -5.159 -2.887 1.00 48.55 ? 39 GLN L NE2 1 ATOM 5586 N N . GLN D 4 39 ? -15.836 -9.023 1.581 1.00 76.79 ? 40 GLN L N 1 ATOM 5587 C CA . GLN D 4 39 ? -15.641 -8.656 2.941 1.00 76.79 ? 40 GLN L CA 1 ATOM 5588 C C . GLN D 4 39 ? -14.297 -8.007 3.237 1.00 76.79 ? 40 GLN L C 1 ATOM 5589 O O . GLN D 4 39 ? -13.230 -8.558 3.094 1.00 76.79 ? 40 GLN L O 1 ATOM 5590 C CB . GLN D 4 39 ? -15.942 -9.915 3.787 1.00 57.94 ? 40 GLN L CB 1 ATOM 5591 C CG . GLN D 4 39 ? -15.792 -9.752 5.351 1.00 57.94 ? 40 GLN L CG 1 ATOM 5592 C CD . GLN D 4 39 ? -16.088 -10.995 6.233 1.00 57.94 ? 40 GLN L CD 1 ATOM 5593 O OE1 . GLN D 4 39 ? -15.647 -12.103 5.993 1.00 57.94 ? 40 GLN L OE1 1 ATOM 5594 N NE2 . GLN D 4 39 ? -16.841 -10.760 7.273 1.00 57.94 ? 40 GLN L NE2 1 ATOM 5595 N N . LEU D 4 40 ? -14.430 -6.767 3.616 1.00 95.95 ? 41 LEU L N 1 ATOM 5596 C CA . LEU D 4 40 ? -13.368 -5.969 4.054 1.00 95.95 ? 41 LEU L CA 1 ATOM 5597 C C . LEU D 4 40 ? -12.762 -6.308 5.378 1.00 95.95 ? 41 LEU L C 1 ATOM 5598 O O . LEU D 4 40 ? -13.340 -7.050 6.177 1.00 95.95 ? 41 LEU L O 1 ATOM 5599 C CB . LEU D 4 40 ? -13.695 -4.515 3.940 1.00 65.61 ? 41 LEU L CB 1 ATOM 5600 C CG . LEU D 4 40 ? -13.759 -4.065 2.522 1.00 65.61 ? 41 LEU L CG 1 ATOM 5601 C CD1 . LEU D 4 40 ? -14.272 -2.653 2.422 1.00 65.61 ? 41 LEU L CD1 1 ATOM 5602 C CD2 . LEU D 4 40 ? -12.363 -4.089 2.017 1.00 65.61 ? 41 LEU L CD2 1 ATOM 5603 N N . PRO D 4 41 ? -11.526 -5.843 5.607 1.00 68.61 ? 42 PRO L N 1 ATOM 5604 C CA . PRO D 4 41 ? -10.862 -6.113 6.885 1.00 68.61 ? 42 PRO L CA 1 ATOM 5605 C C . PRO D 4 41 ? -11.761 -6.044 8.154 1.00 68.61 ? 42 PRO L C 1 ATOM 5606 O O . PRO D 4 41 ? -12.182 -4.945 8.574 1.00 68.61 ? 42 PRO L O 1 ATOM 5607 C CB . PRO D 4 41 ? -9.776 -5.037 6.904 1.00 54.60 ? 42 PRO L CB 1 ATOM 5608 C CG . PRO D 4 41 ? -9.479 -4.798 5.452 1.00 54.60 ? 42 PRO L CG 1 ATOM 5609 C CD . PRO D 4 41 ? -10.801 -4.809 4.828 1.00 54.60 ? 42 PRO L CD 1 ATOM 5610 N N . GLY D 4 42 ? -12.232 -7.185 8.632 1.00 50.68 ? 43 GLY L N 1 ATOM 5611 C CA . GLY D 4 42 ? -12.924 -7.129 9.918 1.00 50.68 ? 43 GLY L CA 1 ATOM 5612 C C . GLY D 4 42 ? -14.278 -6.459 10.013 1.00 50.68 ? 43 GLY L C 1 ATOM 5613 O O . GLY D 4 42 ? -14.785 -6.142 11.075 1.00 50.68 ? 43 GLY L O 1 ATOM 5614 N N . ALA D 4 43 ? -14.890 -6.320 8.850 1.00 52.51 ? 44 ALA L N 1 ATOM 5615 C CA . ALA D 4 43 ? -16.186 -5.695 8.619 1.00 52.51 ? 44 ALA L CA 1 ATOM 5616 C C . ALA D 4 43 ? -17.282 -6.709 8.221 1.00 52.51 ? 44 ALA L C 1 ATOM 5617 O O . ALA D 4 43 ? -17.011 -7.889 7.967 1.00 52.51 ? 44 ALA L O 1 ATOM 5618 C CB . ALA D 4 43 ? -16.060 -4.609 7.581 1.00 101.12 ? 44 ALA L CB 1 ATOM 5619 N N . ALA D 4 44 ? -18.536 -6.332 8.343 1.00 54.16 ? 45 ALA L N 1 ATOM 5620 C CA . ALA D 4 44 ? -19.500 -7.288 7.938 1.00 54.16 ? 45 ALA L CA 1 ATOM 5621 C C . ALA D 4 44 ? -19.429 -7.416 6.429 1.00 54.16 ? 45 ALA L C 1 ATOM 5622 O O . ALA D 4 44 ? -19.149 -6.401 5.726 1.00 54.16 ? 45 ALA L O 1 ATOM 5623 C CB . ALA D 4 44 ? -20.815 -6.814 8.319 1.00 75.92 ? 45 ALA L CB 1 ATOM 5624 N N . PRO D 4 45 ? -19.753 -8.649 5.896 1.00 82.81 ? 46 PRO L N 1 ATOM 5625 C CA . PRO D 4 45 ? -19.742 -8.940 4.474 1.00 82.81 ? 46 PRO L CA 1 ATOM 5626 C C . PRO D 4 45 ? -20.872 -8.149 3.879 1.00 82.81 ? 46 PRO L C 1 ATOM 5627 O O . PRO D 4 45 ? -21.921 -8.015 4.483 1.00 82.81 ? 46 PRO L O 1 ATOM 5628 C CB . PRO D 4 45 ? -20.037 -10.429 4.433 1.00 18.51 ? 46 PRO L CB 1 ATOM 5629 C CG . PRO D 4 45 ? -19.482 -11.010 5.633 1.00 18.51 ? 46 PRO L CG 1 ATOM 5630 C CD . PRO D 4 45 ? -19.997 -9.927 6.614 1.00 18.51 ? 46 PRO L CD 1 ATOM 5631 N N . LYS D 4 46 ? -20.613 -7.669 2.680 1.00 60.21 ? 47 LYS L N 1 ATOM 5632 C CA . LYS D 4 46 ? -21.406 -6.827 1.757 1.00 60.21 ? 47 LYS L CA 1 ATOM 5633 C C . LYS D 4 46 ? -21.777 -7.557 0.441 1.00 60.21 ? 47 LYS L C 1 ATOM 5634 O O . LYS D 4 46 ? -21.014 -8.448 -0.015 1.00 60.21 ? 47 LYS L O 1 ATOM 5635 C CB . LYS D 4 46 ? -20.669 -5.566 1.395 1.00 54.40 ? 47 LYS L CB 1 ATOM 5636 C CG . LYS D 4 46 ? -21.374 -4.691 0.498 1.00 54.40 ? 47 LYS L CG 1 ATOM 5637 C CD . LYS D 4 46 ? -20.591 -3.429 0.235 1.00 54.40 ? 47 LYS L CD 1 ATOM 5638 C CE . LYS D 4 46 ? -19.349 -3.684 -0.567 1.00 54.40 ? 47 LYS L CE 1 ATOM 5639 N NZ . LYS D 4 46 ? -18.567 -2.464 -0.895 1.00 54.40 ? 47 LYS L NZ 1 ATOM 5640 N N . LEU D 4 47 ? -22.955 -7.308 -0.145 1.00 64.69 ? 48 LEU L N 1 ATOM 5641 C CA . LEU D 4 47 ? -23.258 -8.029 -1.370 1.00 64.69 ? 48 LEU L CA 1 ATOM 5642 C C . LEU D 4 47 ? -22.629 -7.362 -2.591 1.00 64.69 ? 48 LEU L C 1 ATOM 5643 O O . LEU D 4 47 ? -23.103 -6.356 -3.060 1.00 64.69 ? 48 LEU L O 1 ATOM 5644 C CB . LEU D 4 47 ? -24.740 -7.878 -1.518 1.00 60.03 ? 48 LEU L CB 1 ATOM 5645 C CG . LEU D 4 47 ? -25.413 -8.477 -2.738 1.00 60.03 ? 48 LEU L CG 1 ATOM 5646 C CD1 . LEU D 4 47 ? -25.203 -9.999 -2.815 1.00 60.03 ? 48 LEU L CD1 1 ATOM 5647 C CD2 . LEU D 4 47 ? -26.834 -8.080 -2.693 1.00 60.03 ? 48 LEU L CD2 1 ATOM 5648 N N . LEU D 4 48 ? -21.518 -7.927 -3.084 1.00 56.20 ? 49 LEU L N 1 ATOM 5649 C CA . LEU D 4 48 ? -20.816 -7.361 -4.252 1.00 56.20 ? 49 LEU L CA 1 ATOM 5650 C C . LEU D 4 48 ? -21.532 -7.503 -5.506 1.00 56.20 ? 49 LEU L C 1 ATOM 5651 O O . LEU D 4 48 ? -21.535 -6.581 -6.296 1.00 56.20 ? 49 LEU L O 1 ATOM 5652 C CB . LEU D 4 48 ? -19.405 -7.993 -4.411 1.00 59.42 ? 49 LEU L CB 1 ATOM 5653 C CG . LEU D 4 48 ? -18.469 -7.602 -5.518 1.00 59.42 ? 49 LEU L CG 1 ATOM 5654 C CD1 . LEU D 4 48 ? -18.120 -6.208 -5.319 1.00 59.42 ? 49 LEU L CD1 1 ATOM 5655 C CD2 . LEU D 4 48 ? -17.235 -8.399 -5.493 1.00 59.42 ? 49 LEU L CD2 1 ATOM 5656 N N . ILE D 4 49 ? -22.142 -8.699 -5.631 1.00 43.72 ? 50 ILE L N 1 ATOM 5657 C CA . ILE D 4 49 ? -22.995 -9.213 -6.743 1.00 43.72 ? 50 ILE L CA 1 ATOM 5658 C C . ILE D 4 49 ? -24.286 -10.067 -6.477 1.00 43.72 ? 50 ILE L C 1 ATOM 5659 O O . ILE D 4 49 ? -24.261 -10.841 -5.540 1.00 43.72 ? 50 ILE L O 1 ATOM 5660 C CB . ILE D 4 49 ? -22.194 -9.802 -8.015 1.00 33.45 ? 50 ILE L CB 1 ATOM 5661 C CG1 . ILE D 4 49 ? -21.352 -8.720 -8.674 1.00 33.45 ? 50 ILE L CG1 1 ATOM 5662 C CG2 . ILE D 4 49 ? -23.123 -10.233 -9.080 1.00 33.45 ? 50 ILE L CG2 1 ATOM 5663 C CD1 . ILE D 4 49 ? -20.460 -9.235 -9.734 1.00 33.45 ? 50 ILE L CD1 1 ATOM 5664 N N . PHE D 4 50 ? -25.420 -9.893 -7.202 1.00 54.99 ? 51 PHE L N 1 ATOM 5665 C CA . PHE D 4 50 ? -26.606 -10.792 -6.980 1.00 54.99 ? 51 PHE L CA 1 ATOM 5666 C C . PHE D 4 50 ? -27.246 -11.057 -8.347 1.00 54.99 ? 51 PHE L C 1 ATOM 5667 O O . PHE D 4 50 ? -27.110 -10.263 -9.296 1.00 54.99 ? 51 PHE L O 1 ATOM 5668 C CB . PHE D 4 50 ? -27.639 -10.151 -6.086 1.00 67.36 ? 51 PHE L CB 1 ATOM 5669 C CG . PHE D 4 50 ? -28.347 -9.025 -6.712 1.00 67.36 ? 51 PHE L CG 1 ATOM 5670 C CD1 . PHE D 4 50 ? -29.464 -9.246 -7.395 1.00 67.36 ? 51 PHE L CD1 1 ATOM 5671 C CD2 . PHE D 4 50 ? -27.781 -7.798 -6.825 1.00 67.36 ? 51 PHE L CD2 1 ATOM 5672 C CE1 . PHE D 4 50 ? -30.019 -8.266 -8.194 1.00 67.36 ? 51 PHE L CE1 1 ATOM 5673 C CE2 . PHE D 4 50 ? -28.325 -6.820 -7.622 1.00 67.36 ? 51 PHE L CE2 1 ATOM 5674 C CZ . PHE D 4 50 ? -29.436 -7.054 -8.301 1.00 67.36 ? 51 PHE L CZ 1 ATOM 5675 N N . ASP D 4 51 ? -28.024 -12.136 -8.415 1.00 71.84 ? 52 ASP L N 1 ATOM 5676 C CA . ASP D 4 51 ? -28.600 -12.629 -9.671 1.00 71.84 ? 52 ASP L CA 1 ATOM 5677 C C . ASP D 4 51 ? -27.611 -12.792 -10.828 1.00 71.84 ? 52 ASP L C 1 ATOM 5678 O O . ASP D 4 51 ? -27.793 -12.278 -11.848 1.00 71.84 ? 52 ASP L O 1 ATOM 5679 C CB . ASP D 4 51 ? -29.881 -11.879 -10.100 1.00 87.01 ? 52 ASP L CB 1 ATOM 5680 C CG . ASP D 4 51 ? -31.064 -12.183 -9.195 1.00 87.01 ? 52 ASP L CG 1 ATOM 5681 O OD1 . ASP D 4 51 ? -32.082 -11.494 -9.238 1.00 87.01 ? 52 ASP L OD1 1 ATOM 5682 O OD2 . ASP D 4 51 ? -30.962 -13.103 -8.391 1.00 87.01 ? 52 ASP L OD2 1 ATOM 5683 N N . ASP D 4 52 ? -26.485 -13.408 -10.585 1.00 43.50 ? 53 ASP L N 1 ATOM 5684 C CA . ASP D 4 52 ? -25.515 -13.743 -11.584 1.00 43.50 ? 53 ASP L CA 1 ATOM 5685 C C . ASP D 4 52 ? -24.804 -12.575 -12.150 1.00 43.50 ? 53 ASP L C 1 ATOM 5686 O O . ASP D 4 52 ? -23.574 -12.520 -12.108 1.00 43.50 ? 53 ASP L O 1 ATOM 5687 C CB . ASP D 4 52 ? -26.156 -14.468 -12.772 1.00 91.35 ? 53 ASP L CB 1 ATOM 5688 C CG . ASP D 4 52 ? -26.633 -15.889 -12.450 1.00 91.35 ? 53 ASP L CG 1 ATOM 5689 O OD1 . ASP D 4 52 ? -26.154 -16.479 -11.457 1.00 91.35 ? 53 ASP L OD1 1 ATOM 5690 O OD2 . ASP D 4 52 ? -27.512 -16.407 -13.210 1.00 91.35 ? 53 ASP L OD2 1 ATOM 5691 N N . THR D 4 53 ? -25.517 -11.662 -12.765 1.00 66.15 ? 54 THR L N 1 ATOM 5692 C CA . THR D 4 53 ? -24.808 -10.535 -13.321 1.00 66.15 ? 54 THR L CA 1 ATOM 5693 C C . THR D 4 53 ? -25.219 -9.207 -12.768 1.00 66.15 ? 54 THR L C 1 ATOM 5694 O O . THR D 4 53 ? -24.821 -8.189 -13.369 1.00 66.15 ? 54 THR L O 1 ATOM 5695 C CB . THR D 4 53 ? -24.987 -10.424 -14.788 1.00 78.84 ? 54 THR L CB 1 ATOM 5696 O OG1 . THR D 4 53 ? -26.319 -10.035 -15.114 1.00 78.84 ? 54 THR L OG1 1 ATOM 5697 C CG2 . THR D 4 53 ? -24.815 -11.800 -15.341 1.00 78.84 ? 54 THR L CG2 1 ATOM 5698 N N . GLN D 4 54 ? -26.027 -9.158 -11.698 1.00 48.83 ? 55 GLN L N 1 ATOM 5699 C CA . GLN D 4 54 ? -26.483 -7.824 -11.337 1.00 48.83 ? 55 GLN L CA 1 ATOM 5700 C C . GLN D 4 54 ? -25.765 -7.181 -10.181 1.00 48.83 ? 55 GLN L C 1 ATOM 5701 O O . GLN D 4 54 ? -25.879 -7.611 -9.059 1.00 48.83 ? 55 GLN L O 1 ATOM 5702 C CB . GLN D 4 54 ? -27.995 -7.847 -11.030 1.00 57.44 ? 55 GLN L CB 1 ATOM 5703 C CG . GLN D 4 54 ? -28.909 -8.295 -12.149 1.00 57.44 ? 55 GLN L CG 1 ATOM 5704 C CD . GLN D 4 54 ? -28.805 -7.464 -13.306 1.00 57.44 ? 55 GLN L CD 1 ATOM 5705 O OE1 . GLN D 4 54 ? -28.700 -6.253 -13.207 1.00 57.44 ? 55 GLN L OE1 1 ATOM 5706 N NE2 . GLN D 4 54 ? -28.811 -8.097 -14.459 1.00 57.44 ? 55 GLN L NE2 1 ATOM 5707 N N . ARG D 4 55 ? -25.159 -6.046 -10.476 1.00 98.08 ? 56 ARG L N 1 ATOM 5708 C CA . ARG D 4 55 ? -24.432 -5.236 -9.531 1.00 98.08 ? 56 ARG L CA 1 ATOM 5709 C C . ARG D 4 55 ? -25.408 -4.202 -8.887 1.00 98.08 ? 56 ARG L C 1 ATOM 5710 O O . ARG D 4 55 ? -26.159 -3.508 -9.579 1.00 98.08 ? 56 ARG L O 1 ATOM 5711 C CB . ARG D 4 55 ? -23.268 -4.560 -10.267 1.00 83.45 ? 56 ARG L CB 1 ATOM 5712 C CG . ARG D 4 55 ? -22.331 -3.858 -9.401 1.00 83.45 ? 56 ARG L CG 1 ATOM 5713 C CD . ARG D 4 55 ? -21.208 -3.223 -10.180 1.00 83.45 ? 56 ARG L CD 1 ATOM 5714 N NE . ARG D 4 55 ? -21.694 -2.175 -11.031 1.00 83.45 ? 56 ARG L NE 1 ATOM 5715 C CZ . ARG D 4 55 ? -22.044 -2.378 -12.275 1.00 83.45 ? 56 ARG L CZ 1 ATOM 5716 N NH1 . ARG D 4 55 ? -21.919 -3.606 -12.767 1.00 83.45 ? 56 ARG L NH1 1 ATOM 5717 N NH2 . ARG D 4 55 ? -22.564 -1.370 -12.985 1.00 83.45 ? 56 ARG L NH2 1 ATOM 5718 N N . PRO D 4 56 ? -25.432 -4.095 -7.556 1.00 68.17 ? 57 PRO L N 1 ATOM 5719 C CA . PRO D 4 56 ? -26.291 -3.169 -6.836 1.00 68.17 ? 57 PRO L CA 1 ATOM 5720 C C . PRO D 4 56 ? -25.697 -1.827 -6.807 1.00 68.17 ? 57 PRO L C 1 ATOM 5721 O O . PRO D 4 56 ? -24.607 -1.731 -7.118 1.00 68.17 ? 57 PRO L O 1 ATOM 5722 C CB . PRO D 4 56 ? -26.318 -3.772 -5.460 1.00 62.51 ? 57 PRO L CB 1 ATOM 5723 C CG . PRO D 4 56 ? -25.075 -4.381 -5.322 1.00 62.51 ? 57 PRO L CG 1 ATOM 5724 C CD . PRO D 4 56 ? -24.908 -5.078 -6.620 1.00 62.51 ? 57 PRO L CD 1 ATOM 5725 N N . SER D 4 57 ? -26.398 -0.800 -6.399 1.00 76.01 ? 58 SER L N 1 ATOM 5726 C CA . SER D 4 57 ? -25.879 0.558 -6.315 1.00 76.01 ? 58 SER L CA 1 ATOM 5727 C C . SER D 4 57 ? -24.708 0.856 -5.435 1.00 76.01 ? 58 SER L C 1 ATOM 5728 O O . SER D 4 57 ? -24.600 0.272 -4.406 1.00 76.01 ? 58 SER L O 1 ATOM 5729 C CB . SER D 4 57 ? -26.915 1.540 -5.899 1.00 87.64 ? 58 SER L CB 1 ATOM 5730 O OG . SER D 4 57 ? -26.306 2.826 -5.849 1.00 87.64 ? 58 SER L OG 1 ATOM 5731 N N . GLY D 4 58 ? -23.795 1.708 -5.907 1.00 81.66 ? 59 GLY L N 1 ATOM 5732 C CA . GLY D 4 58 ? -22.587 2.104 -5.185 1.00 81.66 ? 59 GLY L CA 1 ATOM 5733 C C . GLY D 4 58 ? -21.334 1.225 -5.427 1.00 81.66 ? 59 GLY L C 1 ATOM 5734 O O . GLY D 4 58 ? -20.229 1.526 -4.958 1.00 81.66 ? 59 GLY L O 1 ATOM 5735 N N . ILE D 4 59 ? -21.520 0.083 -6.098 1.00 105.33 ? 60 ILE L N 1 ATOM 5736 C CA . ILE D 4 59 ? -20.433 -0.807 -6.520 1.00 105.33 ? 60 ILE L CA 1 ATOM 5737 C C . ILE D 4 59 ? -19.868 -0.146 -7.808 1.00 105.33 ? 60 ILE L C 1 ATOM 5738 O O . ILE D 4 59 ? -20.599 0.407 -8.638 1.00 105.33 ? 60 ILE L O 1 ATOM 5739 C CB . ILE D 4 59 ? -20.934 -2.220 -6.887 1.00 49.70 ? 60 ILE L CB 1 ATOM 5740 C CG1 . ILE D 4 59 ? -21.632 -2.889 -5.723 1.00 49.70 ? 60 ILE L CG1 1 ATOM 5741 C CG2 . ILE D 4 59 ? -19.745 -3.061 -7.236 1.00 49.70 ? 60 ILE L CG2 1 ATOM 5742 C CD1 . ILE D 4 59 ? -20.787 -3.195 -4.570 1.00 49.70 ? 60 ILE L CD1 1 ATOM 5743 N N . PRO D 4 60 ? -18.572 -0.154 -7.983 1.00 65.09 ? 61 PRO L N 1 ATOM 5744 C CA . PRO D 4 60 ? -18.281 0.499 -9.251 1.00 65.09 ? 61 PRO L CA 1 ATOM 5745 C C . PRO D 4 60 ? -18.354 -0.529 -10.417 1.00 65.09 ? 61 PRO L C 1 ATOM 5746 O O . PRO D 4 60 ? -18.196 -1.726 -10.193 1.00 65.09 ? 61 PRO L O 1 ATOM 5747 C CB . PRO D 4 60 ? -16.873 1.060 -9.009 1.00 87.88 ? 61 PRO L CB 1 ATOM 5748 C CG . PRO D 4 60 ? -16.240 0.068 -8.068 1.00 87.88 ? 61 PRO L CG 1 ATOM 5749 C CD . PRO D 4 60 ? -17.380 -0.252 -7.129 1.00 87.88 ? 61 PRO L CD 1 ATOM 5750 N N . ASP D 4 61 ? -18.318 -0.035 -11.653 1.00 88.00 ? 62 ASP L N 1 ATOM 5751 C CA . ASP D 4 61 ? -18.471 -0.837 -12.860 1.00 88.00 ? 62 ASP L CA 1 ATOM 5752 C C . ASP D 4 61 ? -17.276 -1.741 -13.106 1.00 88.00 ? 62 ASP L C 1 ATOM 5753 O O . ASP D 4 61 ? -17.277 -2.551 -14.000 1.00 88.00 ? 62 ASP L O 1 ATOM 5754 C CB . ASP D 4 61 ? -18.979 0.027 -14.038 1.00 92.97 ? 62 ASP L CB 1 ATOM 5755 C CG . ASP D 4 61 ? -18.042 1.186 -14.401 1.00 92.97 ? 62 ASP L CG 1 ATOM 5756 O OD1 . ASP D 4 61 ? -17.212 1.571 -13.541 1.00 92.97 ? 62 ASP L OD1 1 ATOM 5757 O OD2 . ASP D 4 61 ? -18.151 1.750 -15.533 1.00 92.97 ? 62 ASP L OD2 1 ATOM 5758 N N . ARG D 4 62 ? -16.235 -1.556 -12.300 1.00 56.32 ? 63 ARG L N 1 ATOM 5759 C CA . ARG D 4 62 ? -15.041 -2.394 -12.339 1.00 56.32 ? 63 ARG L CA 1 ATOM 5760 C C . ARG D 4 62 ? -15.566 -3.799 -12.036 1.00 56.32 ? 63 ARG L C 1 ATOM 5761 O O . ARG D 4 62 ? -14.987 -4.748 -12.457 1.00 56.32 ? 63 ARG L O 1 ATOM 5762 C CB . ARG D 4 62 ? -13.939 -1.976 -11.366 1.00 79.26 ? 63 ARG L CB 1 ATOM 5763 C CG . ARG D 4 62 ? -13.252 -0.632 -11.777 1.00 79.26 ? 63 ARG L CG 1 ATOM 5764 C CD . ARG D 4 62 ? -12.119 -0.156 -10.818 1.00 79.26 ? 63 ARG L CD 1 ATOM 5765 N NE . ARG D 4 62 ? -12.570 0.071 -9.459 1.00 79.26 ? 63 ARG L NE 1 ATOM 5766 C CZ . ARG D 4 62 ? -12.156 -0.720 -8.502 1.00 79.26 ? 63 ARG L CZ 1 ATOM 5767 N NH1 . ARG D 4 62 ? -11.313 -1.664 -8.864 1.00 79.26 ? 63 ARG L NH1 1 ATOM 5768 N NH2 . ARG D 4 62 ? -12.646 -0.648 -7.272 1.00 79.26 ? 63 ARG L NH2 1 ATOM 5769 N N . PHE D 4 63 ? -16.499 -3.950 -11.120 1.00 56.61 ? 64 PHE L N 1 ATOM 5770 C CA . PHE D 4 63 ? -17.030 -5.287 -10.812 1.00 56.61 ? 64 PHE L CA 1 ATOM 5771 C C . PHE D 4 63 ? -18.025 -5.924 -11.782 1.00 56.61 ? 64 PHE L C 1 ATOM 5772 O O . PHE D 4 63 ? -19.013 -5.322 -12.153 1.00 56.61 ? 64 PHE L O 1 ATOM 5773 C CB . PHE D 4 63 ? -17.681 -5.290 -9.390 1.00 81.00 ? 64 PHE L CB 1 ATOM 5774 C CG . PHE D 4 63 ? -16.725 -5.025 -8.307 1.00 81.00 ? 64 PHE L CG 1 ATOM 5775 C CD1 . PHE D 4 63 ? -16.031 -6.063 -7.759 1.00 81.00 ? 64 PHE L CD1 1 ATOM 5776 C CD2 . PHE D 4 63 ? -16.360 -3.732 -7.995 1.00 81.00 ? 64 PHE L CD2 1 ATOM 5777 C CE1 . PHE D 4 63 ? -14.960 -5.829 -6.956 1.00 81.00 ? 64 PHE L CE1 1 ATOM 5778 C CE2 . PHE D 4 63 ? -15.265 -3.480 -7.171 1.00 81.00 ? 64 PHE L CE2 1 ATOM 5779 C CZ . PHE D 4 63 ? -14.562 -4.529 -6.663 1.00 81.00 ? 64 PHE L CZ 1 ATOM 5780 N N . SER D 4 64 ? -17.811 -7.184 -12.120 1.00 58.51 ? 65 SER L N 1 ATOM 5781 C CA . SER D 4 64 ? -18.717 -7.887 -13.012 1.00 58.51 ? 65 SER L CA 1 ATOM 5782 C C . SER D 4 64 ? -18.994 -9.354 -12.640 1.00 58.51 ? 65 SER L C 1 ATOM 5783 O O . SER D 4 64 ? -18.206 -9.942 -11.970 1.00 58.51 ? 65 SER L O 1 ATOM 5784 C CB . SER D 4 64 ? -18.154 -7.783 -14.446 1.00 132.84 ? 65 SER L CB 1 ATOM 5785 O OG . SER D 4 64 ? -16.857 -8.360 -14.563 1.00 132.84 ? 65 SER L OG 1 ATOM 5786 N N . GLY D 4 65 ? -20.076 -9.964 -13.119 1.00 65.84 ? 66 GLY L N 1 ATOM 5787 C CA . GLY D 4 65 ? -20.316 -11.381 -12.848 1.00 65.84 ? 66 GLY L CA 1 ATOM 5788 C C . GLY D 4 65 ? -20.752 -12.225 -14.080 1.00 65.84 ? 66 GLY L C 1 ATOM 5789 O O . GLY D 4 65 ? -21.184 -11.701 -15.138 1.00 65.84 ? 66 GLY L O 1 ATOM 5790 N N . SER D 4 66 ? -20.539 -13.538 -14.010 1.00 59.17 ? 67 SER L N 1 ATOM 5791 C CA . SER D 4 66 ? -20.995 -14.436 -15.069 1.00 59.17 ? 67 SER L CA 1 ATOM 5792 C C . SER D 4 66 ? -21.361 -15.773 -14.473 1.00 59.17 ? 67 SER L C 1 ATOM 5793 O O . SER D 4 66 ? -20.974 -16.092 -13.339 1.00 59.17 ? 67 SER L O 1 ATOM 5794 C CB . SER D 4 66 ? -19.945 -14.729 -16.079 1.00 77.68 ? 67 SER L CB 1 ATOM 5795 O OG . SER D 4 66 ? -18.994 -15.521 -15.470 1.00 77.68 ? 67 SER L OG 1 ATOM 5796 N N . LYS D 4 67 ? -22.235 -16.482 -15.171 1.00 114.79 ? 68 LYS L N 1 ATOM 5797 C CA . LYS D 4 67 ? -22.630 -17.825 -14.798 1.00 114.79 ? 68 LYS L CA 1 ATOM 5798 C C . LYS D 4 67 ? -22.767 -18.719 -16.017 1.00 114.79 ? 68 LYS L C 1 ATOM 5799 O O . LYS D 4 67 ? -23.277 -18.261 -17.018 1.00 114.79 ? 68 LYS L O 1 ATOM 5800 C CB . LYS D 4 67 ? -23.924 -17.811 -14.058 1.00 64.92 ? 68 LYS L CB 1 ATOM 5801 C CG . LYS D 4 67 ? -24.253 -19.160 -13.602 1.00 64.92 ? 68 LYS L CG 1 ATOM 5802 C CD . LYS D 4 67 ? -25.563 -19.184 -12.841 1.00 64.92 ? 68 LYS L CD 1 ATOM 5803 C CE . LYS D 4 67 ? -25.853 -20.591 -12.383 1.00 64.92 ? 68 LYS L CE 1 ATOM 5804 N NZ . LYS D 4 67 ? -26.350 -21.392 -13.482 1.00 64.92 ? 68 LYS L NZ 1 ATOM 5805 N N . SER D 4 68 ? -22.276 -19.946 -16.010 1.00 93.64 ? 69 SER L N 1 ATOM 5806 C CA . SER D 4 68 ? -22.484 -20.849 -17.155 1.00 93.64 ? 69 SER L CA 1 ATOM 5807 C C . SER D 4 68 ? -22.264 -22.272 -16.666 1.00 93.64 ? 69 SER L C 1 ATOM 5808 O O . SER D 4 68 ? -21.467 -22.513 -15.785 1.00 93.64 ? 69 SER L O 1 ATOM 5809 C CB . SER D 4 68 ? -21.544 -20.496 -18.326 1.00 129.22 ? 69 SER L CB 1 ATOM 5810 O OG . SER D 4 68 ? -21.741 -21.338 -19.455 1.00 129.22 ? 69 SER L OG 1 ATOM 5811 N N . GLY D 4 69 ? -22.925 -23.236 -17.247 1.00 111.78 ? 70 GLY L N 1 ATOM 5812 C CA . GLY D 4 69 ? -22.726 -24.581 -16.766 1.00 111.78 ? 70 GLY L CA 1 ATOM 5813 C C . GLY D 4 69 ? -22.949 -24.645 -15.264 1.00 111.78 ? 70 GLY L C 1 ATOM 5814 O O . GLY D 4 69 ? -23.783 -23.912 -14.733 1.00 111.78 ? 70 GLY L O 1 ATOM 5815 N N . THR D 4 70 ? -22.122 -25.418 -14.562 1.00 93.44 ? 71 THR L N 1 ATOM 5816 C CA . THR D 4 70 ? -22.273 -25.581 -13.109 1.00 93.44 ? 71 THR L CA 1 ATOM 5817 C C . THR D 4 70 ? -21.207 -24.836 -12.305 1.00 93.44 ? 71 THR L C 1 ATOM 5818 O O . THR D 4 70 ? -20.843 -25.200 -11.188 1.00 93.44 ? 71 THR L O 1 ATOM 5819 C CB . THR D 4 70 ? -22.353 -27.084 -12.689 1.00 72.10 ? 71 THR L CB 1 ATOM 5820 O OG1 . THR D 4 70 ? -23.487 -27.260 -11.836 1.00 72.10 ? 71 THR L OG1 1 ATOM 5821 C CG2 . THR D 4 70 ? -21.060 -27.564 -11.998 1.00 72.10 ? 71 THR L CG2 1 ATOM 5822 N N . SER D 4 71 ? -20.730 -23.749 -12.886 1.00 106.94 ? 72 SER L N 1 ATOM 5823 C CA . SER D 4 71 ? -19.757 -22.946 -12.197 1.00 106.94 ? 72 SER L CA 1 ATOM 5824 C C . SER D 4 71 ? -20.175 -21.509 -12.513 1.00 106.94 ? 72 SER L C 1 ATOM 5825 O O . SER D 4 71 ? -20.909 -21.289 -13.449 1.00 106.94 ? 72 SER L O 1 ATOM 5826 C CB . SER D 4 71 ? -18.354 -23.176 -12.775 1.00 60.69 ? 72 SER L CB 1 ATOM 5827 O OG . SER D 4 71 ? -18.234 -22.633 -14.075 1.00 60.69 ? 72 SER L OG 1 ATOM 5828 N N . ALA D 4 72 ? -19.755 -20.554 -11.687 1.00 44.49 ? 73 ALA L N 1 ATOM 5829 C CA . ALA D 4 72 ? -19.978 -19.114 -11.870 1.00 44.49 ? 73 ALA L CA 1 ATOM 5830 C C . ALA D 4 72 ? -18.641 -18.422 -11.582 1.00 44.49 ? 73 ALA L C 1 ATOM 5831 O O . ALA D 4 72 ? -17.900 -18.868 -10.737 1.00 44.49 ? 73 ALA L O 1 ATOM 5832 C CB . ALA D 4 72 ? -21.025 -18.641 -10.935 1.00 109.50 ? 73 ALA L CB 1 ATOM 5833 N N . THR D 4 73 ? -18.385 -17.322 -12.251 1.00 54.25 ? 74 THR L N 1 ATOM 5834 C CA . THR D 4 73 ? -17.172 -16.506 -12.227 1.00 54.25 ? 74 THR L CA 1 ATOM 5835 C C . THR D 4 73 ? -17.232 -15.064 -11.805 1.00 54.25 ? 74 THR L C 1 ATOM 5836 O O . THR D 4 73 ? -18.089 -14.358 -12.268 1.00 54.25 ? 74 THR L O 1 ATOM 5837 C CB . THR D 4 73 ? -16.454 -16.503 -13.548 1.00 56.29 ? 74 THR L CB 1 ATOM 5838 O OG1 . THR D 4 73 ? -16.080 -17.839 -13.885 1.00 56.29 ? 74 THR L OG1 1 ATOM 5839 C CG2 . THR D 4 73 ? -15.284 -15.561 -13.527 1.00 56.29 ? 74 THR L CG2 1 ATOM 5840 N N . LEU D 4 74 ? -16.390 -14.604 -10.894 1.00 65.77 ? 75 LEU L N 1 ATOM 5841 C CA . LEU D 4 74 ? -16.458 -13.184 -10.493 1.00 65.77 ? 75 LEU L CA 1 ATOM 5842 C C . LEU D 4 74 ? -15.281 -12.413 -11.242 1.00 65.77 ? 75 LEU L C 1 ATOM 5843 O O . LEU D 4 74 ? -14.219 -12.933 -11.382 1.00 65.77 ? 75 LEU L O 1 ATOM 5844 C CB . LEU D 4 74 ? -16.375 -13.071 -8.943 1.00 42.27 ? 75 LEU L CB 1 ATOM 5845 C CG . LEU D 4 74 ? -16.451 -11.736 -8.223 1.00 42.27 ? 75 LEU L CG 1 ATOM 5846 C CD1 . LEU D 4 74 ? -17.856 -11.430 -8.475 1.00 42.27 ? 75 LEU L CD1 1 ATOM 5847 C CD2 . LEU D 4 74 ? -16.282 -11.749 -6.792 1.00 42.27 ? 75 LEU L CD2 1 ATOM 5848 N N . ALA D 4 75 ? -15.548 -11.277 -11.869 1.00 67.35 ? 76 ALA L N 1 ATOM 5849 C CA . ALA D 4 75 ? -14.511 -10.527 -12.543 1.00 67.35 ? 76 ALA L CA 1 ATOM 5850 C C . ALA D 4 75 ? -14.262 -9.092 -12.049 1.00 67.35 ? 76 ALA L C 1 ATOM 5851 O O . ALA D 4 75 ? -15.179 -8.353 -11.788 1.00 67.35 ? 76 ALA L O 1 ATOM 5852 C CB . ALA D 4 75 ? -14.815 -10.496 -14.023 1.00 116.25 ? 76 ALA L CB 1 ATOM 5853 N N . ILE D 4 76 ? -12.994 -8.761 -11.874 1.00 62.26 ? 77 ILE L N 1 ATOM 5854 C CA . ILE D 4 76 ? -12.410 -7.486 -11.445 1.00 62.26 ? 77 ILE L CA 1 ATOM 5855 C C . ILE D 4 76 ? -11.404 -6.700 -12.371 1.00 62.26 ? 77 ILE L C 1 ATOM 5856 O O . ILE D 4 76 ? -10.469 -7.284 -12.938 1.00 62.26 ? 77 ILE L O 1 ATOM 5857 C CB . ILE D 4 76 ? -11.891 -7.563 -9.936 1.00 55.44 ? 77 ILE L CB 1 ATOM 5858 C CG1 . ILE D 4 76 ? -13.002 -7.885 -9.009 1.00 55.44 ? 77 ILE L CG1 1 ATOM 5859 C CG2 . ILE D 4 76 ? -11.416 -6.255 -9.401 1.00 55.44 ? 77 ILE L CG2 1 ATOM 5860 C CD1 . ILE D 4 76 ? -12.599 -8.211 -7.606 1.00 55.44 ? 77 ILE L CD1 1 ATOM 5861 N N . THR D 4 77 ? -11.611 -5.408 -12.602 1.00 87.06 ? 78 THR L N 1 ATOM 5862 C CA . THR D 4 77 ? -10.635 -4.696 -13.426 1.00 87.06 ? 78 THR L CA 1 ATOM 5863 C C . THR D 4 77 ? -10.063 -3.400 -12.810 1.00 87.06 ? 78 THR L C 1 ATOM 5864 O O . THR D 4 77 ? -10.707 -2.765 -11.956 1.00 87.06 ? 78 THR L O 1 ATOM 5865 C CB . THR D 4 77 ? -11.267 -4.274 -14.697 1.00 84.26 ? 78 THR L CB 1 ATOM 5866 O OG1 . THR D 4 77 ? -12.299 -3.343 -14.393 1.00 84.26 ? 78 THR L OG1 1 ATOM 5867 C CG2 . THR D 4 77 ? -11.910 -5.450 -15.381 1.00 84.26 ? 78 THR L CG2 1 ATOM 5868 N N . GLY D 4 78 ? -8.822 -3.042 -13.176 1.00 72.67 ? 79 GLY L N 1 ATOM 5869 C CA . GLY D 4 78 ? -8.313 -1.792 -12.652 1.00 72.67 ? 79 GLY L CA 1 ATOM 5870 C C . GLY D 4 78 ? -8.094 -2.045 -11.189 1.00 72.67 ? 79 GLY L C 1 ATOM 5871 O O . GLY D 4 78 ? -8.245 -1.098 -10.428 1.00 72.67 ? 79 GLY L O 1 ATOM 5872 N N . LEU D 4 79 ? -7.641 -3.233 -10.765 1.00 52.35 ? 80 LEU L N 1 ATOM 5873 C CA . LEU D 4 79 ? -7.711 -3.554 -9.327 1.00 52.35 ? 80 LEU L CA 1 ATOM 5874 C C . LEU D 4 79 ? -6.933 -2.580 -8.535 1.00 52.35 ? 80 LEU L C 1 ATOM 5875 O O . LEU D 4 79 ? -5.924 -2.162 -8.923 1.00 52.35 ? 80 LEU L O 1 ATOM 5876 C CB . LEU D 4 79 ? -7.242 -5.005 -9.165 1.00 52.28 ? 80 LEU L CB 1 ATOM 5877 C CG . LEU D 4 79 ? -7.133 -5.793 -7.893 1.00 52.28 ? 80 LEU L CG 1 ATOM 5878 C CD1 . LEU D 4 79 ? -8.479 -5.910 -7.206 1.00 52.28 ? 80 LEU L CD1 1 ATOM 5879 C CD2 . LEU D 4 79 ? -6.769 -7.161 -8.313 1.00 52.28 ? 80 LEU L CD2 1 ATOM 5880 N N . GLN D 4 80 ? -7.507 -2.218 -7.402 1.00 89.18 ? 81 GLN L N 1 ATOM 5881 C CA . GLN D 4 80 ? -7.089 -1.122 -6.501 1.00 89.18 ? 81 GLN L CA 1 ATOM 5882 C C . GLN D 4 80 ? -6.500 -1.624 -5.157 1.00 89.18 ? 81 GLN L C 1 ATOM 5883 O O . GLN D 4 80 ? -6.681 -2.778 -4.782 1.00 89.18 ? 81 GLN L O 1 ATOM 5884 C CB . GLN D 4 80 ? -8.343 -0.311 -6.214 1.00 104.42 ? 81 GLN L CB 1 ATOM 5885 C CG . GLN D 4 80 ? -8.843 0.466 -7.392 1.00 104.42 ? 81 GLN L CG 1 ATOM 5886 C CD . GLN D 4 80 ? -10.109 1.279 -7.083 1.00 104.42 ? 81 GLN L CD 1 ATOM 5887 O OE1 . GLN D 4 80 ? -10.547 2.124 -7.873 1.00 104.42 ? 81 GLN L OE1 1 ATOM 5888 N NE2 . GLN D 4 80 ? -10.720 0.998 -5.945 1.00 104.42 ? 81 GLN L NE2 1 ATOM 5889 N N . THR D 4 81 ? -5.695 -0.803 -4.504 1.00 80.84 ? 82 THR L N 1 ATOM 5890 C CA . THR D 4 81 ? -5.146 -1.137 -3.210 1.00 80.84 ? 82 THR L CA 1 ATOM 5891 C C . THR D 4 81 ? -6.431 -1.319 -2.367 1.00 80.84 ? 82 THR L C 1 ATOM 5892 O O . THR D 4 81 ? -6.522 -2.197 -1.519 1.00 80.84 ? 82 THR L O 1 ATOM 5893 C CB . THR D 4 81 ? -4.289 0.003 -2.632 1.00 79.06 ? 82 THR L CB 1 ATOM 5894 O OG1 . THR D 4 81 ? -5.133 1.093 -2.275 1.00 79.06 ? 82 THR L OG1 1 ATOM 5895 C CG2 . THR D 4 81 ? -3.344 0.546 -3.663 1.00 79.06 ? 82 THR L CG2 1 ATOM 5896 N N . GLY D 4 82 ? -7.410 -0.449 -2.601 1.00 73.72 ? 83 GLY L N 1 ATOM 5897 C CA . GLY D 4 82 ? -8.688 -0.456 -1.883 1.00 73.72 ? 83 GLY L CA 1 ATOM 5898 C C . GLY D 4 82 ? -9.498 -1.747 -1.954 1.00 73.72 ? 83 GLY L C 1 ATOM 5899 O O . GLY D 4 82 ? -10.145 -2.120 -0.993 1.00 73.72 ? 83 GLY L O 1 ATOM 5900 N N . ASP D 4 83 ? -9.390 -2.453 -3.072 1.00 78.19 ? 84 ASP L N 1 ATOM 5901 C CA . ASP D 4 83 ? -10.089 -3.713 -3.381 1.00 78.19 ? 84 ASP L CA 1 ATOM 5902 C C . ASP D 4 83 ? -9.634 -4.908 -2.553 1.00 78.19 ? 84 ASP L C 1 ATOM 5903 O O . ASP D 4 83 ? -10.129 -6.024 -2.765 1.00 78.19 ? 84 ASP L O 1 ATOM 5904 C CB . ASP D 4 83 ? -10.050 -4.123 -4.869 1.00 116.56 ? 84 ASP L CB 1 ATOM 5905 C CG . ASP D 4 83 ? -10.881 -3.233 -5.749 1.00 116.56 ? 84 ASP L CG 1 ATOM 5906 O OD1 . ASP D 4 83 ? -11.785 -2.541 -5.226 1.00 116.56 ? 84 ASP L OD1 1 ATOM 5907 O OD2 . ASP D 4 83 ? -10.669 -3.272 -6.979 1.00 116.56 ? 84 ASP L OD2 1 ATOM 5908 N N . GLU D 4 84 ? -8.541 -4.765 -1.830 1.00 73.28 ? 85 GLU L N 1 ATOM 5909 C CA . GLU D 4 84 ? -8.150 -5.877 -1.016 1.00 73.28 ? 85 GLU L CA 1 ATOM 5910 C C . GLU D 4 84 ? -9.271 -6.167 -0.041 1.00 73.28 ? 85 GLU L C 1 ATOM 5911 O O . GLU D 4 84 ? -9.899 -5.249 0.434 1.00 73.28 ? 85 GLU L O 1 ATOM 5912 C CB . GLU D 4 84 ? -6.772 -5.529 -0.429 1.00 93.05 ? 85 GLU L CB 1 ATOM 5913 C CG . GLU D 4 84 ? -6.101 -6.521 0.478 1.00 93.05 ? 85 GLU L CG 1 ATOM 5914 C CD . GLU D 4 84 ? -4.765 -6.015 0.916 1.00 93.05 ? 85 GLU L CD 1 ATOM 5915 O OE1 . GLU D 4 84 ? -4.317 -4.999 0.355 1.00 93.05 ? 85 GLU L OE1 1 ATOM 5916 O OE2 . GLU D 4 84 ? -4.145 -6.642 1.786 1.00 93.05 ? 85 GLU L OE2 1 ATOM 5917 N N . ALA D 4 85 ? -9.585 -7.456 0.128 1.00 61.57 ? 86 ALA L N 1 ATOM 5918 C CA . ALA D 4 85 ? -10.681 -7.962 0.973 1.00 61.57 ? 86 ALA L CA 1 ATOM 5919 C C . ALA D 4 85 ? -10.816 -9.431 0.666 1.00 61.57 ? 86 ALA L C 1 ATOM 5920 O O . ALA D 4 85 ? -9.876 -9.992 0.125 1.00 61.57 ? 86 ALA L O 1 ATOM 5921 C CB . ALA D 4 85 ? -11.955 -7.262 0.737 1.00 108.05 ? 86 ALA L CB 1 ATOM 5922 N N . ASP D 4 86 ? -11.877 -10.076 1.152 1.00 74.89 ? 87 ASP L N 1 ATOM 5923 C CA . ASP D 4 86 ? -12.083 -11.517 0.927 1.00 74.89 ? 87 ASP L CA 1 ATOM 5924 C C . ASP D 4 86 ? -13.420 -11.729 0.170 1.00 74.89 ? 87 ASP L C 1 ATOM 5925 O O . ASP D 4 86 ? -14.433 -11.250 0.679 1.00 74.89 ? 87 ASP L O 1 ATOM 5926 C CB . ASP D 4 86 ? -12.247 -12.249 2.265 1.00 68.96 ? 87 ASP L CB 1 ATOM 5927 C CG . ASP D 4 86 ? -10.982 -12.320 3.076 1.00 68.96 ? 87 ASP L CG 1 ATOM 5928 O OD1 . ASP D 4 86 ? -9.875 -12.127 2.539 1.00 68.96 ? 87 ASP L OD1 1 ATOM 5929 O OD2 . ASP D 4 86 ? -11.103 -12.608 4.260 1.00 68.96 ? 87 ASP L OD2 1 ATOM 5930 N N . TYR D 4 87 ? -13.504 -12.503 -0.933 1.00 65.63 ? 88 TYR L N 1 ATOM 5931 C CA . TYR D 4 87 ? -14.816 -12.609 -1.640 1.00 65.63 ? 88 TYR L CA 1 ATOM 5932 C C . TYR D 4 87 ? -15.497 -14.012 -1.511 1.00 65.63 ? 88 TYR L C 1 ATOM 5933 O O . TYR D 4 87 ? -14.848 -15.048 -1.768 1.00 65.63 ? 88 TYR L O 1 ATOM 5934 C CB . TYR D 4 87 ? -14.631 -12.303 -3.154 1.00 69.66 ? 88 TYR L CB 1 ATOM 5935 C CG . TYR D 4 87 ? -14.098 -10.940 -3.405 1.00 69.66 ? 88 TYR L CG 1 ATOM 5936 C CD1 . TYR D 4 87 ? -14.907 -9.830 -3.351 1.00 69.66 ? 88 TYR L CD1 1 ATOM 5937 C CD2 . TYR D 4 87 ? -12.752 -10.775 -3.626 1.00 69.66 ? 88 TYR L CD2 1 ATOM 5938 C CE1 . TYR D 4 87 ? -14.384 -8.575 -3.458 1.00 69.66 ? 88 TYR L CE1 1 ATOM 5939 C CE2 . TYR D 4 87 ? -12.198 -9.546 -3.758 1.00 69.66 ? 88 TYR L CE2 1 ATOM 5940 C CZ . TYR D 4 87 ? -13.003 -8.441 -3.658 1.00 69.66 ? 88 TYR L CZ 1 ATOM 5941 O OH . TYR D 4 87 ? -12.365 -7.217 -3.695 1.00 69.66 ? 88 TYR L OH 1 ATOM 5942 N N . TYR D 4 88 ? -16.819 -14.041 -1.248 1.00 62.78 ? 89 TYR L N 1 ATOM 5943 C CA . TYR D 4 88 ? -17.516 -15.344 -1.086 1.00 62.78 ? 89 TYR L CA 1 ATOM 5944 C C . TYR D 4 88 ? -18.685 -15.586 -2.124 1.00 62.78 ? 89 TYR L C 1 ATOM 5945 O O . TYR D 4 88 ? -19.486 -14.672 -2.343 1.00 62.78 ? 89 TYR L O 1 ATOM 5946 C CB . TYR D 4 88 ? -18.151 -15.375 0.310 1.00 68.63 ? 89 TYR L CB 1 ATOM 5947 C CG . TYR D 4 88 ? -17.165 -15.476 1.477 1.00 68.63 ? 89 TYR L CG 1 ATOM 5948 C CD1 . TYR D 4 88 ? -16.736 -16.696 1.998 1.00 68.63 ? 89 TYR L CD1 1 ATOM 5949 C CD2 . TYR D 4 88 ? -16.704 -14.340 2.103 1.00 68.63 ? 89 TYR L CD2 1 ATOM 5950 C CE1 . TYR D 4 88 ? -15.851 -16.769 3.088 1.00 68.63 ? 89 TYR L CE1 1 ATOM 5951 C CE2 . TYR D 4 88 ? -15.823 -14.424 3.203 1.00 68.63 ? 89 TYR L CE2 1 ATOM 5952 C CZ . TYR D 4 88 ? -15.402 -15.640 3.663 1.00 68.63 ? 89 TYR L CZ 1 ATOM 5953 O OH . TYR D 4 88 ? -14.447 -15.702 4.616 1.00 68.63 ? 89 TYR L OH 1 ATOM 5954 N N . CYS D 4 89 ? -18.850 -16.812 -2.664 1.00 61.93 ? 90 CYS L N 1 ATOM 5955 C CA . CYS D 4 89 ? -19.917 -17.017 -3.625 1.00 61.93 ? 90 CYS L CA 1 ATOM 5956 C C . CYS D 4 89 ? -21.112 -17.740 -3.004 1.00 61.93 ? 90 CYS L C 1 ATOM 5957 O O . CYS D 4 89 ? -20.995 -18.802 -2.404 1.00 61.93 ? 90 CYS L O 1 ATOM 5958 C CB . CYS D 4 89 ? -19.440 -17.814 -4.822 1.00 80.74 ? 90 CYS L CB 1 ATOM 5959 S SG . CYS D 4 89 ? -19.067 -19.532 -4.442 1.00 80.74 ? 90 CYS L SG 1 ATOM 5960 N N . GLY D 4 90 ? -22.280 -17.114 -3.127 1.00 97.42 ? 91 GLY L N 1 ATOM 5961 C CA . GLY D 4 90 ? -23.527 -17.648 -2.583 1.00 97.42 ? 91 GLY L CA 1 ATOM 5962 C C . GLY D 4 90 ? -24.566 -18.146 -3.565 1.00 97.42 ? 91 GLY L C 1 ATOM 5963 O O . GLY D 4 90 ? -24.953 -17.433 -4.506 1.00 97.42 ? 91 GLY L O 1 ATOM 5964 N N . THR D 4 91 ? -25.102 -19.324 -3.287 1.00 77.39 ? 92 THR L N 1 ATOM 5965 C CA . THR D 4 91 ? -26.076 -19.926 -4.179 1.00 77.39 ? 92 THR L CA 1 ATOM 5966 C C . THR D 4 91 ? -27.110 -20.529 -3.217 1.00 77.39 ? 92 THR L C 1 ATOM 5967 O O . THR D 4 91 ? -26.729 -20.915 -2.149 1.00 77.39 ? 92 THR L O 1 ATOM 5968 C CB . THR D 4 91 ? -25.395 -20.982 -4.999 1.00 113.17 ? 92 THR L CB 1 ATOM 5969 O OG1 . THR D 4 91 ? -26.261 -21.422 -6.031 1.00 113.17 ? 92 THR L OG1 1 ATOM 5970 C CG2 . THR D 4 91 ? -25.042 -22.141 -4.135 1.00 113.17 ? 92 THR L CG2 1 ATOM 5971 N N . TRP D 4 92 ? -28.390 -20.630 -3.590 1.00 55.57 ? 93 TRP L N 1 ATOM 5972 C CA . TRP D 4 92 ? -29.436 -21.064 -2.669 1.00 55.57 ? 93 TRP L CA 1 ATOM 5973 C C . TRP D 4 92 ? -29.490 -22.497 -3.172 1.00 55.57 ? 93 TRP L C 1 ATOM 5974 O O . TRP D 4 92 ? -29.303 -22.669 -4.360 1.00 55.57 ? 93 TRP L O 1 ATOM 5975 C CB . TRP D 4 92 ? -30.738 -20.310 -2.978 1.00 74.11 ? 93 TRP L CB 1 ATOM 5976 C CG . TRP D 4 92 ? -31.722 -20.173 -1.776 1.00 74.11 ? 93 TRP L CG 1 ATOM 5977 C CD1 . TRP D 4 92 ? -31.927 -19.011 -1.075 1.00 74.11 ? 93 TRP L CD1 1 ATOM 5978 C CD2 . TRP D 4 92 ? -32.383 -21.193 -1.014 1.00 74.11 ? 93 TRP L CD2 1 ATOM 5979 N NE1 . TRP D 4 92 ? -32.644 -19.238 0.059 1.00 74.11 ? 93 TRP L NE1 1 ATOM 5980 C CE2 . TRP D 4 92 ? -32.946 -20.564 0.127 1.00 74.11 ? 93 TRP L CE2 1 ATOM 5981 C CE3 . TRP D 4 92 ? -32.556 -22.570 -1.174 1.00 74.11 ? 93 TRP L CE3 1 ATOM 5982 C CZ2 . TRP D 4 92 ? -33.669 -21.257 1.093 1.00 74.11 ? 93 TRP L CZ2 1 ATOM 5983 C CZ3 . TRP D 4 92 ? -33.296 -23.276 -0.182 1.00 74.11 ? 93 TRP L CZ3 1 ATOM 5984 C CH2 . TRP D 4 92 ? -33.836 -22.607 0.927 1.00 74.11 ? 93 TRP L CH2 1 ATOM 5985 N N . ASP D 4 93 ? -29.628 -23.547 -2.356 1.00 98.61 ? 94 ASP L N 1 ATOM 5986 C CA . ASP D 4 93 ? -29.567 -24.890 -2.991 1.00 98.61 ? 94 ASP L CA 1 ATOM 5987 C C . ASP D 4 93 ? -30.831 -25.742 -2.818 1.00 98.61 ? 94 ASP L C 1 ATOM 5988 O O . ASP D 4 93 ? -31.335 -25.863 -1.710 1.00 98.61 ? 94 ASP L O 1 ATOM 5989 C CB . ASP D 4 93 ? -28.433 -25.706 -2.389 1.00 91.67 ? 94 ASP L CB 1 ATOM 5990 C CG . ASP D 4 93 ? -28.164 -26.990 -3.159 1.00 91.67 ? 94 ASP L CG 1 ATOM 5991 O OD1 . ASP D 4 93 ? -27.131 -27.652 -2.874 1.00 91.67 ? 94 ASP L OD1 1 ATOM 5992 O OD2 . ASP D 4 93 ? -28.924 -27.287 -4.103 1.00 91.67 ? 94 ASP L OD2 1 ATOM 5993 N N . SER D 4 94 ? -31.355 -26.301 -3.921 1.00 127.12 ? 95 SER L N 1 ATOM 5994 C CA . SER D 4 94 ? -32.584 -27.152 -3.933 1.00 127.12 ? 95 SER L CA 1 ATOM 5995 C C . SER D 4 94 ? -32.586 -28.530 -3.275 1.00 127.12 ? 95 SER L C 1 ATOM 5996 O O . SER D 4 94 ? -33.597 -28.954 -2.703 1.00 127.12 ? 95 SER L O 1 ATOM 5997 C CB . SER D 4 94 ? -33.114 -27.385 -5.336 1.00 87.90 ? 95 SER L CB 1 ATOM 5998 O OG . SER D 4 94 ? -32.224 -28.239 -5.994 1.00 87.90 ? 95 SER L OG 1 ATOM 5999 N N . SER D 4 95 ? -31.479 -29.258 -3.447 1.00 134.03 ? 96 SER L N 1 ATOM 6000 C CA . SER D 4 95 ? -31.407 -30.638 -2.971 1.00 134.03 ? 96 SER L CA 1 ATOM 6001 C C . SER D 4 95 ? -31.362 -30.828 -1.485 1.00 134.03 ? 96 SER L C 1 ATOM 6002 O O . SER D 4 95 ? -30.900 -29.985 -0.724 1.00 134.03 ? 96 SER L O 1 ATOM 6003 C CB . SER D 4 95 ? -30.145 -31.361 -3.465 1.00 107.98 ? 96 SER L CB 1 ATOM 6004 O OG . SER D 4 95 ? -28.984 -30.855 -2.830 1.00 107.98 ? 96 SER L OG 1 ATOM 6005 N N . LEU D 4 96 ? -31.783 -32.020 -1.108 1.00 100.17 ? 97 LEU L N 1 ATOM 6006 C CA . LEU D 4 96 ? -31.780 -32.468 0.256 1.00 100.17 ? 97 LEU L CA 1 ATOM 6007 C C . LEU D 4 96 ? -32.471 -31.300 0.975 1.00 100.17 ? 97 LEU L C 1 ATOM 6008 O O . LEU D 4 96 ? -33.265 -30.573 0.370 1.00 100.17 ? 97 LEU L O 1 ATOM 6009 C CB . LEU D 4 96 ? -30.287 -32.503 0.618 1.00 109.90 ? 97 LEU L CB 1 ATOM 6010 C CG . LEU D 4 96 ? -29.450 -33.088 1.764 1.00 109.90 ? 97 LEU L CG 1 ATOM 6011 C CD1 . LEU D 4 96 ? -27.968 -33.210 1.270 1.00 109.90 ? 97 LEU L CD1 1 ATOM 6012 C CD2 . LEU D 4 96 ? -29.616 -32.288 3.049 1.00 109.90 ? 97 LEU L CD2 1 ATOM 6013 N N . SER D 4 97 ? -32.274 -31.198 2.288 1.00 118.75 ? 98 SER L N 1 ATOM 6014 C CA . SER D 4 97 ? -32.692 -30.037 3.090 1.00 118.75 ? 98 SER L CA 1 ATOM 6015 C C . SER D 4 97 ? -32.102 -28.709 2.764 1.00 118.75 ? 98 SER L C 1 ATOM 6016 O O . SER D 4 97 ? -32.787 -27.710 2.407 1.00 118.75 ? 98 SER L O 1 ATOM 6017 C CB . SER D 4 97 ? -32.170 -30.108 4.543 1.00 119.00 ? 98 SER L CB 1 ATOM 6018 O OG . SER D 4 97 ? -32.592 -31.176 5.340 1.00 119.00 ? 98 SER L OG 1 ATOM 6019 N N . THR D 4 98 ? -30.814 -28.951 2.493 1.00 166.84 ? 99 THR L N 1 ATOM 6020 C CA . THR D 4 98 ? -29.809 -27.963 2.789 1.00 166.84 ? 99 THR L CA 1 ATOM 6021 C C . THR D 4 98 ? -29.884 -26.480 2.612 1.00 166.84 ? 99 THR L C 1 ATOM 6022 O O . THR D 4 98 ? -29.145 -25.775 3.295 1.00 166.84 ? 99 THR L O 1 ATOM 6023 C CB . THR D 4 98 ? -28.410 -28.514 2.400 1.00 86.78 ? 99 THR L CB 1 ATOM 6024 O OG1 . THR D 4 98 ? -28.469 -29.237 1.172 1.00 86.78 ? 99 THR L OG1 1 ATOM 6025 C CG2 . THR D 4 98 ? -27.932 -29.500 3.492 1.00 86.78 ? 99 THR L CG2 1 ATOM 6026 N N . GLY D 4 99 ? -30.773 -25.956 1.790 1.00 110.72 ? 100 GLY L N 1 ATOM 6027 C CA . GLY D 4 99 ? -30.870 -24.514 1.798 1.00 110.72 ? 100 GLY L CA 1 ATOM 6028 C C . GLY D 4 99 ? -29.721 -23.719 1.234 1.00 110.72 ? 100 GLY L C 1 ATOM 6029 O O . GLY D 4 99 ? -29.034 -24.158 0.322 1.00 110.72 ? 100 GLY L O 1 ATOM 6030 N N . GLN D 4 100 ? -29.543 -22.525 1.781 1.00 75.04 ? 101 GLN L N 1 ATOM 6031 C CA . GLN D 4 100 ? -28.516 -21.573 1.350 1.00 75.04 ? 101 GLN L CA 1 ATOM 6032 C C . GLN D 4 100 ? -27.129 -22.209 1.580 1.00 75.04 ? 101 GLN L C 1 ATOM 6033 O O . GLN D 4 100 ? -26.990 -22.951 2.541 1.00 75.04 ? 101 GLN L O 1 ATOM 6034 C CB . GLN D 4 100 ? -28.625 -20.291 2.183 1.00 89.94 ? 101 GLN L CB 1 ATOM 6035 C CG . GLN D 4 100 ? -27.783 -19.069 1.773 1.00 89.94 ? 101 GLN L CG 1 ATOM 6036 C CD . GLN D 4 100 ? -28.074 -18.548 0.370 1.00 89.94 ? 101 GLN L CD 1 ATOM 6037 O OE1 . GLN D 4 100 ? -29.228 -18.230 0.063 1.00 89.94 ? 101 GLN L OE1 1 ATOM 6038 N NE2 . GLN D 4 100 ? -27.032 -18.411 -0.468 1.00 89.94 ? 101 GLN L NE2 1 ATOM 6039 N N . LEU D 4 101 ? -26.170 -22.028 0.655 1.00 47.77 ? 102 LEU L N 1 ATOM 6040 C CA . LEU D 4 101 ? -24.808 -22.553 0.772 1.00 47.77 ? 102 LEU L CA 1 ATOM 6041 C C . LEU D 4 101 ? -23.788 -21.576 0.336 1.00 47.77 ? 102 LEU L C 1 ATOM 6042 O O . LEU D 4 101 ? -23.913 -20.944 -0.726 1.00 47.77 ? 102 LEU L O 1 ATOM 6043 C CB . LEU D 4 101 ? -24.557 -23.792 -0.108 1.00 75.21 ? 102 LEU L CB 1 ATOM 6044 C CG . LEU D 4 101 ? -25.293 -25.114 0.038 1.00 75.21 ? 102 LEU L CG 1 ATOM 6045 C CD1 . LEU D 4 101 ? -24.826 -26.031 -1.071 1.00 75.21 ? 102 LEU L CD1 1 ATOM 6046 C CD2 . LEU D 4 101 ? -24.995 -25.734 1.426 1.00 75.21 ? 102 LEU L CD2 1 ATOM 6047 N N . PHE D 4 102 ? -22.664 -21.635 1.012 1.00 75.58 ? 103 PHE L N 1 ATOM 6048 C CA . PHE D 4 102 ? -21.530 -20.775 0.757 1.00 75.58 ? 103 PHE L CA 1 ATOM 6049 C C . PHE D 4 102 ? -20.269 -21.505 0.376 1.00 75.58 ? 103 PHE L C 1 ATOM 6050 O O . PHE D 4 102 ? -20.036 -22.577 0.875 1.00 75.58 ? 103 PHE L O 1 ATOM 6051 C CB . PHE D 4 102 ? -21.177 -19.897 1.934 1.00 71.12 ? 103 PHE L CB 1 ATOM 6052 C CG . PHE D 4 102 ? -22.133 -18.839 2.226 1.00 71.12 ? 103 PHE L CG 1 ATOM 6053 C CD1 . PHE D 4 102 ? -22.256 -17.779 1.367 1.00 71.12 ? 103 PHE L CD1 1 ATOM 6054 C CD2 . PHE D 4 102 ? -22.823 -18.830 3.406 1.00 71.12 ? 103 PHE L CD2 1 ATOM 6055 C CE1 . PHE D 4 102 ? -23.062 -16.732 1.673 1.00 71.12 ? 103 PHE L CE1 1 ATOM 6056 C CE2 . PHE D 4 102 ? -23.630 -17.787 3.729 1.00 71.12 ? 103 PHE L CE2 1 ATOM 6057 C CZ . PHE D 4 102 ? -23.757 -16.733 2.859 1.00 71.12 ? 103 PHE L CZ 1 ATOM 6058 N N . GLY D 4 103 ? -19.483 -21.016 -0.567 1.00 100.84 ? 104 GLY L N 1 ATOM 6059 C CA . GLY D 4 103 ? -18.235 -21.718 -0.821 1.00 100.84 ? 104 GLY L CA 1 ATOM 6060 C C . GLY D 4 103 ? -17.286 -21.282 0.296 1.00 100.84 ? 104 GLY L C 1 ATOM 6061 O O . GLY D 4 103 ? -17.587 -20.401 1.046 1.00 100.84 ? 104 GLY L O 1 ATOM 6062 N N . GLY D 4 104 ? -16.123 -21.868 0.419 1.00 87.88 ? 105 GLY L N 1 ATOM 6063 C CA . GLY D 4 104 ? -15.270 -21.482 1.509 1.00 87.88 ? 105 GLY L CA 1 ATOM 6064 C C . GLY D 4 104 ? -14.949 -20.019 1.404 1.00 87.88 ? 105 GLY L C 1 ATOM 6065 O O . GLY D 4 104 ? -14.924 -19.327 2.375 1.00 87.88 ? 105 GLY L O 1 ATOM 6066 N N . GLY D 4 105 ? -14.714 -19.553 0.200 1.00 87.40 ? 106 GLY L N 1 ATOM 6067 C CA . GLY D 4 105 ? -14.343 -18.173 -0.065 1.00 87.40 ? 106 GLY L CA 1 ATOM 6068 C C . GLY D 4 105 ? -12.851 -18.038 -0.360 1.00 87.40 ? 106 GLY L C 1 ATOM 6069 O O . GLY D 4 105 ? -12.108 -18.966 -0.142 1.00 87.40 ? 106 GLY L O 1 ATOM 6070 N N . THR D 4 106 ? -12.393 -16.895 -0.849 1.00 58.41 ? 107 THR L N 1 ATOM 6071 C CA . THR D 4 106 ? -11.002 -16.751 -1.143 1.00 58.41 ? 107 THR L CA 1 ATOM 6072 C C . THR D 4 106 ? -10.562 -15.425 -0.544 1.00 58.41 ? 107 THR L C 1 ATOM 6073 O O . THR D 4 106 ? -11.358 -14.522 -0.395 1.00 58.41 ? 107 THR L O 1 ATOM 6074 C CB . THR D 4 106 ? -10.786 -16.577 -2.597 1.00 37.95 ? 107 THR L CB 1 ATOM 6075 O OG1 . THR D 4 106 ? -10.237 -15.288 -2.802 1.00 37.95 ? 107 THR L OG1 1 ATOM 6076 C CG2 . THR D 4 106 ? -12.031 -16.544 -3.316 1.00 37.95 ? 107 THR L CG2 1 ATOM 6077 N N . LYS D 4 107 ? -9.286 -15.309 -0.230 1.00 60.12 ? 108 LYS L N 1 ATOM 6078 C CA . LYS D 4 107 ? -8.737 -14.068 0.258 1.00 60.12 ? 108 LYS L CA 1 ATOM 6079 C C . LYS D 4 107 ? -7.947 -13.595 -0.946 1.00 60.12 ? 108 LYS L C 1 ATOM 6080 O O . LYS D 4 107 ? -7.165 -14.349 -1.519 1.00 60.12 ? 108 LYS L O 1 ATOM 6081 C CB . LYS D 4 107 ? -7.843 -14.363 1.459 1.00 60.31 ? 108 LYS L CB 1 ATOM 6082 C CG . LYS D 4 107 ? -8.689 -14.641 2.828 1.00 60.31 ? 108 LYS L CG 1 ATOM 6083 C CD . LYS D 4 107 ? -9.504 -16.035 2.838 1.00 60.31 ? 108 LYS L CD 1 ATOM 6084 C CE . LYS D 4 107 ? -10.295 -16.322 4.119 1.00 60.31 ? 108 LYS L CE 1 ATOM 6085 N NZ . LYS D 4 107 ? -11.168 -17.516 3.960 1.00 60.31 ? 108 LYS L NZ 1 ATOM 6086 N N . LEU D 4 108 ? -8.159 -12.342 -1.325 1.00 72.56 ? 109 LEU L N 1 ATOM 6087 C CA . LEU D 4 108 ? -7.548 -11.709 -2.501 1.00 72.56 ? 109 LEU L CA 1 ATOM 6088 C C . LEU D 4 108 ? -6.669 -10.726 -1.948 1.00 72.56 ? 109 LEU L C 1 ATOM 6089 O O . LEU D 4 108 ? -7.041 -10.053 -1.014 1.00 72.56 ? 109 LEU L O 1 ATOM 6090 C CB . LEU D 4 108 ? -8.506 -10.875 -3.339 1.00 70.72 ? 109 LEU L CB 1 ATOM 6091 C CG . LEU D 4 108 ? -7.938 -10.180 -4.589 1.00 70.72 ? 109 LEU L CG 1 ATOM 6092 C CD1 . LEU D 4 108 ? -7.586 -11.206 -5.626 1.00 70.72 ? 109 LEU L CD1 1 ATOM 6093 C CD2 . LEU D 4 108 ? -8.933 -9.225 -5.161 1.00 70.72 ? 109 LEU L CD2 1 ATOM 6094 N N . THR D 4 109 ? -5.512 -10.590 -2.534 1.00 65.96 ? 110 THR L N 1 ATOM 6095 C CA . THR D 4 109 ? -4.569 -9.636 -1.990 1.00 65.96 ? 110 THR L CA 1 ATOM 6096 C C . THR D 4 109 ? -4.023 -8.965 -3.235 1.00 65.96 ? 110 THR L C 1 ATOM 6097 O O . THR D 4 109 ? -3.948 -9.568 -4.291 1.00 65.96 ? 110 THR L O 1 ATOM 6098 C CB . THR D 4 109 ? -3.431 -10.422 -1.065 1.00 51.73 ? 110 THR L CB 1 ATOM 6099 O OG1 . THR D 4 109 ? -2.621 -9.497 -0.332 1.00 51.73 ? 110 THR L OG1 1 ATOM 6100 C CG2 . THR D 4 109 ? -2.480 -11.321 -1.887 1.00 51.73 ? 110 THR L CG2 1 ATOM 6101 N N . VAL D 4 110 ? -3.641 -7.710 -3.096 1.00 68.65 ? 111 VAL L N 1 ATOM 6102 C CA . VAL D 4 110 ? -3.095 -6.928 -4.183 1.00 68.65 ? 111 VAL L CA 1 ATOM 6103 C C . VAL D 4 110 ? -1.744 -6.622 -3.573 1.00 68.65 ? 111 VAL L C 1 ATOM 6104 O O . VAL D 4 110 ? -1.607 -6.561 -2.330 1.00 68.65 ? 111 VAL L O 1 ATOM 6105 C CB . VAL D 4 110 ? -3.931 -5.671 -4.463 1.00 80.07 ? 111 VAL L CB 1 ATOM 6106 C CG1 . VAL D 4 110 ? -5.334 -6.088 -4.831 1.00 80.07 ? 111 VAL L CG1 1 ATOM 6107 C CG2 . VAL D 4 110 ? -3.962 -4.758 -3.282 1.00 80.07 ? 111 VAL L CG2 1 ATOM 6108 N N . LEU D 4 111 ? -0.726 -6.459 -4.409 1.00 63.54 ? 112 LEU L N 1 ATOM 6109 C CA . LEU D 4 111 ? 0.596 -6.310 -3.840 1.00 63.54 ? 112 LEU L CA 1 ATOM 6110 C C . LEU D 4 111 ? 0.869 -4.826 -3.862 1.00 63.54 ? 112 LEU L C 1 ATOM 6111 O O . LEU D 4 111 ? 0.798 -4.213 -4.871 1.00 63.54 ? 112 LEU L O 1 ATOM 6112 C CB . LEU D 4 111 ? 1.569 -7.079 -4.758 1.00 63.21 ? 112 LEU L CB 1 ATOM 6113 C CG . LEU D 4 111 ? 1.474 -8.617 -4.754 1.00 63.21 ? 112 LEU L CG 1 ATOM 6114 C CD1 . LEU D 4 111 ? 0.333 -9.087 -5.616 1.00 63.21 ? 112 LEU L CD1 1 ATOM 6115 C CD2 . LEU D 4 111 ? 2.737 -9.205 -5.252 1.00 63.21 ? 112 LEU L CD2 1 ATOM 6116 N N . GLY D 4 112 ? 1.101 -4.221 -2.720 1.00 105.73 ? 113 GLY L N 1 ATOM 6117 C CA . GLY D 4 112 ? 1.419 -2.808 -2.728 1.00 105.73 ? 113 GLY L CA 1 ATOM 6118 C C . GLY D 4 112 ? 2.905 -2.613 -2.504 1.00 105.73 ? 113 GLY L C 1 ATOM 6119 O O . GLY D 4 112 ? 3.419 -1.501 -2.517 1.00 105.73 ? 113 GLY L O 1 ATOM 6120 N N . GLN D 4 113 ? 3.584 -3.724 -2.246 1.00 53.77 ? 114 GLN L N 1 ATOM 6121 C CA . GLN D 4 113 ? 4.997 -3.781 -1.924 1.00 53.77 ? 114 GLN L CA 1 ATOM 6122 C C . GLN D 4 113 ? 5.873 -4.746 -2.672 1.00 53.77 ? 114 GLN L C 1 ATOM 6123 O O . GLN D 4 113 ? 5.420 -5.680 -3.315 1.00 53.77 ? 114 GLN L O 1 ATOM 6124 C CB . GLN D 4 113 ? 5.200 -4.107 -0.458 1.00 61.38 ? 114 GLN L CB 1 ATOM 6125 C CG . GLN D 4 113 ? 4.832 -3.068 0.507 1.00 61.38 ? 114 GLN L CG 1 ATOM 6126 C CD . GLN D 4 113 ? 4.303 -3.730 1.741 1.00 61.38 ? 114 GLN L CD 1 ATOM 6127 O OE1 . GLN D 4 113 ? 3.092 -3.968 1.837 1.00 61.38 ? 114 GLN L OE1 1 ATOM 6128 N NE2 . GLN D 4 113 ? 5.198 -4.081 2.678 1.00 61.38 ? 114 GLN L NE2 1 ATOM 6129 N N . PRO D 4 114 ? 7.173 -4.492 -2.611 1.00 87.03 ? 115 PRO L N 1 ATOM 6130 C CA . PRO D 4 114 ? 8.180 -5.325 -3.221 1.00 87.03 ? 115 PRO L CA 1 ATOM 6131 C C . PRO D 4 114 ? 8.209 -6.506 -2.238 1.00 87.03 ? 115 PRO L C 1 ATOM 6132 O O . PRO D 4 114 ? 7.943 -6.336 -1.063 1.00 87.03 ? 115 PRO L O 1 ATOM 6133 C CB . PRO D 4 114 ? 9.402 -4.461 -3.090 1.00 46.30 ? 115 PRO L CB 1 ATOM 6134 C CG . PRO D 4 114 ? 9.189 -3.773 -1.785 1.00 46.30 ? 115 PRO L CG 1 ATOM 6135 C CD . PRO D 4 114 ? 7.797 -3.299 -2.015 1.00 46.30 ? 115 PRO L CD 1 ATOM 6136 N N . LYS D 4 115 ? 8.622 -7.676 -2.667 1.00 85.66 ? 116 LYS L N 1 ATOM 6137 C CA . LYS D 4 115 ? 8.589 -8.792 -1.751 1.00 85.66 ? 116 LYS L CA 1 ATOM 6138 C C . LYS D 4 115 ? 9.489 -8.421 -0.563 1.00 85.66 ? 116 LYS L C 1 ATOM 6139 O O . LYS D 4 115 ? 10.557 -7.828 -0.677 1.00 85.66 ? 116 LYS L O 1 ATOM 6140 C CB . LYS D 4 115 ? 9.184 -9.991 -2.464 1.00 72.40 ? 116 LYS L CB 1 ATOM 6141 C CG . LYS D 4 115 ? 9.261 -11.276 -1.739 1.00 72.40 ? 116 LYS L CG 1 ATOM 6142 C CD . LYS D 4 115 ? 9.885 -12.254 -2.687 1.00 72.40 ? 116 LYS L CD 1 ATOM 6143 C CE . LYS D 4 115 ? 10.036 -13.606 -2.114 1.00 72.40 ? 116 LYS L CE 1 ATOM 6144 N NZ . LYS D 4 115 ? 10.679 -14.524 -3.112 1.00 72.40 ? 116 LYS L NZ 1 ATOM 6145 N N . ALA D 4 116 ? 9.033 -8.744 0.619 1.00 107.94 ? 117 ALA L N 1 ATOM 6146 C CA . ALA D 4 116 ? 9.847 -8.449 1.786 1.00 107.94 ? 117 ALA L CA 1 ATOM 6147 C C . ALA D 4 116 ? 10.140 -9.713 2.619 1.00 107.94 ? 117 ALA L C 1 ATOM 6148 O O . ALA D 4 116 ? 9.246 -10.508 2.904 1.00 107.94 ? 117 ALA L O 1 ATOM 6149 C CB . ALA D 4 116 ? 9.174 -7.394 2.632 1.00 74.78 ? 117 ALA L CB 1 ATOM 6150 N N . ALA D 4 117 ? 11.410 -9.932 2.950 1.00 77.95 ? 118 ALA L N 1 ATOM 6151 C CA . ALA D 4 117 ? 11.821 -11.070 3.749 1.00 77.95 ? 118 ALA L CA 1 ATOM 6152 C C . ALA D 4 117 ? 11.363 -10.940 5.165 1.00 77.95 ? 118 ALA L C 1 ATOM 6153 O O . ALA D 4 117 ? 11.278 -9.847 5.675 1.00 77.95 ? 118 ALA L O 1 ATOM 6154 C CB . ALA D 4 117 ? 13.287 -11.189 3.703 1.00 90.32 ? 118 ALA L CB 1 ATOM 6155 N N . PRO D 4 118 ? 11.107 -12.051 5.836 1.00 99.62 ? 119 PRO L N 1 ATOM 6156 C CA . PRO D 4 118 ? 10.666 -12.041 7.239 1.00 99.62 ? 119 PRO L CA 1 ATOM 6157 C C . PRO D 4 118 ? 11.870 -11.782 8.082 1.00 99.62 ? 119 PRO L C 1 ATOM 6158 O O . PRO D 4 118 ? 12.935 -12.169 7.678 1.00 99.62 ? 119 PRO L O 1 ATOM 6159 C CB . PRO D 4 118 ? 10.189 -13.455 7.472 1.00 59.57 ? 119 PRO L CB 1 ATOM 6160 C CG . PRO D 4 118 ? 11.010 -14.212 6.516 1.00 59.57 ? 119 PRO L CG 1 ATOM 6161 C CD . PRO D 4 118 ? 10.998 -13.384 5.251 1.00 59.57 ? 119 PRO L CD 1 ATOM 6162 N N . SER D 4 119 ? 11.734 -11.174 9.261 1.00 76.79 ? 120 SER L N 1 ATOM 6163 C CA . SER D 4 119 ? 12.922 -10.979 10.100 1.00 76.79 ? 120 SER L CA 1 ATOM 6164 C C . SER D 4 119 ? 12.515 -11.742 11.322 1.00 76.79 ? 120 SER L C 1 ATOM 6165 O O . SER D 4 119 ? 11.490 -11.464 11.899 1.00 76.79 ? 120 SER L O 1 ATOM 6166 C CB . SER D 4 119 ? 13.105 -9.515 10.445 1.00 111.87 ? 120 SER L CB 1 ATOM 6167 O OG . SER D 4 119 ? 14.253 -9.376 11.250 1.00 111.87 ? 120 SER L OG 1 ATOM 6168 N N . VAL D 4 120 ? 13.358 -12.644 11.781 1.00 69.00 ? 121 VAL L N 1 ATOM 6169 C CA . VAL D 4 120 ? 12.903 -13.456 12.882 1.00 69.00 ? 121 VAL L CA 1 ATOM 6170 C C . VAL D 4 120 ? 13.734 -13.355 14.142 1.00 69.00 ? 121 VAL L C 1 ATOM 6171 O O . VAL D 4 120 ? 14.979 -13.438 14.043 1.00 69.00 ? 121 VAL L O 1 ATOM 6172 C CB . VAL D 4 120 ? 12.875 -14.919 12.523 1.00 47.96 ? 121 VAL L CB 1 ATOM 6173 C CG1 . VAL D 4 120 ? 12.371 -15.752 13.762 1.00 47.96 ? 121 VAL L CG1 1 ATOM 6174 C CG2 . VAL D 4 120 ? 12.070 -15.114 11.283 1.00 47.96 ? 121 VAL L CG2 1 ATOM 6175 N N . THR D 4 121 ? 13.107 -13.126 15.307 1.00 67.93 ? 122 THR L N 1 ATOM 6176 C CA . THR D 4 121 ? 13.948 -13.108 16.494 1.00 67.93 ? 122 THR L CA 1 ATOM 6177 C C . THR D 4 121 ? 13.142 -14.057 17.331 1.00 67.93 ? 122 THR L C 1 ATOM 6178 O O . THR D 4 121 ? 11.941 -13.981 17.250 1.00 67.93 ? 122 THR L O 1 ATOM 6179 C CB . THR D 4 121 ? 13.926 -11.787 17.239 1.00 89.27 ? 122 THR L CB 1 ATOM 6180 O OG1 . THR D 4 121 ? 12.753 -11.701 18.047 1.00 89.27 ? 122 THR L OG1 1 ATOM 6181 C CG2 . THR D 4 121 ? 13.850 -10.630 16.227 1.00 89.27 ? 122 THR L CG2 1 ATOM 6182 N N . LEU D 4 122 ? 13.765 -14.910 18.144 1.00 102.19 ? 123 LEU L N 1 ATOM 6183 C CA . LEU D 4 122 ? 13.032 -15.885 18.958 1.00 102.19 ? 123 LEU L CA 1 ATOM 6184 C C . LEU D 4 122 ? 13.306 -15.660 20.430 1.00 102.19 ? 123 LEU L C 1 ATOM 6185 O O . LEU D 4 122 ? 14.432 -15.378 20.805 1.00 102.19 ? 123 LEU L O 1 ATOM 6186 C CB . LEU D 4 122 ? 13.418 -17.325 18.570 1.00 137.11 ? 123 LEU L CB 1 ATOM 6187 C CG . LEU D 4 122 ? 12.797 -18.556 19.268 1.00 137.11 ? 123 LEU L CG 1 ATOM 6188 C CD1 . LEU D 4 122 ? 12.808 -19.719 18.300 1.00 137.11 ? 123 LEU L CD1 1 ATOM 6189 C CD2 . LEU D 4 122 ? 13.527 -18.933 20.533 1.00 137.11 ? 123 LEU L CD2 1 ATOM 6190 N N . PHE D 4 123 ? 12.301 -15.776 21.287 1.00 142.28 ? 124 PHE L N 1 ATOM 6191 C CA . PHE D 4 123 ? 12.615 -15.576 22.685 1.00 142.28 ? 124 PHE L CA 1 ATOM 6192 C C . PHE D 4 123 ? 12.320 -16.854 23.481 1.00 142.28 ? 124 PHE L C 1 ATOM 6193 O O . PHE D 4 123 ? 11.425 -17.649 23.123 1.00 142.28 ? 124 PHE L O 1 ATOM 6194 C CB . PHE D 4 123 ? 11.714 -14.509 23.307 1.00 81.80 ? 124 PHE L CB 1 ATOM 6195 C CG . PHE D 4 123 ? 11.932 -13.151 22.822 1.00 81.80 ? 124 PHE L CG 1 ATOM 6196 C CD1 . PHE D 4 123 ? 13.191 -12.656 22.642 1.00 81.80 ? 124 PHE L CD1 1 ATOM 6197 C CD2 . PHE D 4 123 ? 10.855 -12.329 22.607 1.00 81.80 ? 124 PHE L CD2 1 ATOM 6198 C CE1 . PHE D 4 123 ? 13.387 -11.337 22.251 1.00 81.80 ? 124 PHE L CE1 1 ATOM 6199 C CE2 . PHE D 4 123 ? 11.029 -11.016 22.216 1.00 81.80 ? 124 PHE L CE2 1 ATOM 6200 C CZ . PHE D 4 123 ? 12.305 -10.515 22.036 1.00 81.80 ? 124 PHE L CZ 1 ATOM 6201 N N . PRO D 4 124 ? 13.103 -17.055 24.576 1.00 80.66 ? 125 PRO L N 1 ATOM 6202 C CA . PRO D 4 124 ? 13.277 -17.996 25.649 1.00 80.66 ? 125 PRO L CA 1 ATOM 6203 C C . PRO D 4 124 ? 12.200 -17.857 26.689 1.00 80.66 ? 125 PRO L C 1 ATOM 6204 O O . PRO D 4 124 ? 11.508 -16.846 26.724 1.00 80.66 ? 125 PRO L O 1 ATOM 6205 C CB . PRO D 4 124 ? 14.628 -17.614 26.080 1.00 85.18 ? 125 PRO L CB 1 ATOM 6206 C CG . PRO D 4 124 ? 14.347 -16.253 26.424 1.00 85.18 ? 125 PRO L CG 1 ATOM 6207 C CD . PRO D 4 124 ? 13.828 -15.840 25.034 1.00 85.18 ? 125 PRO L CD 1 ATOM 6208 N N . PRO D 4 125 ? 11.991 -18.894 27.505 1.00 120.16 ? 126 PRO L N 1 ATOM 6209 C CA . PRO D 4 125 ? 10.969 -18.824 28.553 1.00 120.16 ? 126 PRO L CA 1 ATOM 6210 C C . PRO D 4 125 ? 11.449 -17.817 29.603 1.00 120.16 ? 126 PRO L C 1 ATOM 6211 O O . PRO D 4 125 ? 12.642 -17.667 29.769 1.00 120.16 ? 126 PRO L O 1 ATOM 6212 C CB . PRO D 4 125 ? 10.941 -20.249 29.100 1.00 82.19 ? 126 PRO L CB 1 ATOM 6213 C CG . PRO D 4 125 ? 11.403 -21.094 27.959 1.00 82.19 ? 126 PRO L CG 1 ATOM 6214 C CD . PRO D 4 125 ? 12.538 -20.256 27.390 1.00 82.19 ? 126 PRO L CD 1 ATOM 6215 N N . SER D 4 126 ? 10.542 -17.089 30.258 1.00 111.08 ? 127 SER L N 1 ATOM 6216 C CA . SER D 4 126 ? 10.918 -16.112 31.296 1.00 111.08 ? 127 SER L CA 1 ATOM 6217 C C . SER D 4 126 ? 11.437 -16.792 32.558 1.00 111.08 ? 127 SER L C 1 ATOM 6218 O O . SER D 4 126 ? 11.023 -17.915 32.855 1.00 111.08 ? 127 SER L O 1 ATOM 6219 C CB . SER D 4 126 ? 9.710 -15.269 31.680 1.00 130.87 ? 127 SER L CB 1 ATOM 6220 O OG . SER D 4 126 ? 9.234 -14.571 30.566 1.00 130.87 ? 127 SER L OG 1 ATOM 6221 N N . SER D 4 127 ? 12.340 -16.163 33.316 1.00 85.78 ? 128 SER L N 1 ATOM 6222 C CA . SER D 4 127 ? 12.721 -16.867 34.517 1.00 85.78 ? 128 SER L CA 1 ATOM 6223 C C . SER D 4 127 ? 11.472 -16.955 35.399 1.00 85.78 ? 128 SER L C 1 ATOM 6224 O O . SER D 4 127 ? 11.139 -18.022 35.928 1.00 85.78 ? 128 SER L O 1 ATOM 6225 C CB . SER D 4 127 ? 13.730 -16.034 35.307 1.00 80.56 ? 128 SER L CB 1 ATOM 6226 O OG . SER D 4 127 ? 13.109 -14.860 35.884 1.00 80.56 ? 128 SER L OG 1 ATOM 6227 N N . GLU D 4 128 ? 10.706 -15.862 35.425 1.00 88.43 ? 129 GLU L N 1 ATOM 6228 C CA . GLU D 4 128 ? 9.613 -15.852 36.333 1.00 88.43 ? 129 GLU L CA 1 ATOM 6229 C C . GLU D 4 128 ? 8.673 -16.976 35.960 1.00 88.43 ? 129 GLU L C 1 ATOM 6230 O O . GLU D 4 128 ? 8.120 -17.680 36.794 1.00 88.43 ? 129 GLU L O 1 ATOM 6231 C CB . GLU D 4 128 ? 8.915 -14.501 36.204 1.00 97.72 ? 129 GLU L CB 1 ATOM 6232 C CG . GLU D 4 128 ? 9.777 -13.395 36.766 1.00 97.72 ? 129 GLU L CG 1 ATOM 6233 C CD . GLU D 4 128 ? 9.177 -12.003 36.686 1.00 97.72 ? 129 GLU L CD 1 ATOM 6234 O OE1 . GLU D 4 128 ? 9.920 -11.016 36.958 1.00 97.72 ? 129 GLU L OE1 1 ATOM 6235 O OE2 . GLU D 4 128 ? 7.953 -11.896 36.454 1.00 97.72 ? 129 GLU L OE2 1 ATOM 6236 N N . GLU D 4 129 ? 8.497 -17.146 34.665 1.00 76.11 ? 130 GLU L N 1 ATOM 6237 C CA . GLU D 4 129 ? 7.614 -18.182 34.161 1.00 76.11 ? 130 GLU L CA 1 ATOM 6238 C C . GLU D 4 129 ? 7.994 -19.655 34.468 1.00 76.11 ? 130 GLU L C 1 ATOM 6239 O O . GLU D 4 129 ? 7.142 -20.434 34.836 1.00 76.11 ? 130 GLU L O 1 ATOM 6240 C CB . GLU D 4 129 ? 7.395 -17.887 32.679 1.00 132.32 ? 130 GLU L CB 1 ATOM 6241 C CG . GLU D 4 129 ? 6.518 -18.809 31.917 1.00 132.32 ? 130 GLU L CG 1 ATOM 6242 C CD . GLU D 4 129 ? 6.430 -18.354 30.499 1.00 132.32 ? 130 GLU L CD 1 ATOM 6243 O OE1 . GLU D 4 129 ? 6.931 -17.247 30.205 1.00 132.32 ? 130 GLU L OE1 1 ATOM 6244 O OE2 . GLU D 4 129 ? 5.809 -19.059 29.693 1.00 132.32 ? 130 GLU L OE2 1 ATOM 6245 N N . LEU D 4 130 ? 9.273 -20.015 34.402 1.00 75.78 ? 131 LEU L N 1 ATOM 6246 C CA . LEU D 4 130 ? 9.699 -21.363 34.759 1.00 75.78 ? 131 LEU L CA 1 ATOM 6247 C C . LEU D 4 130 ? 9.306 -21.588 36.215 1.00 75.78 ? 131 LEU L C 1 ATOM 6248 O O . LEU D 4 130 ? 8.763 -22.635 36.613 1.00 75.78 ? 131 LEU L O 1 ATOM 6249 C CB . LEU D 4 130 ? 11.200 -21.571 34.593 1.00 65.22 ? 131 LEU L CB 1 ATOM 6250 C CG . LEU D 4 130 ? 11.910 -21.631 33.255 1.00 65.22 ? 131 LEU L CG 1 ATOM 6251 C CD1 . LEU D 4 130 ? 11.284 -20.728 32.327 1.00 65.22 ? 131 LEU L CD1 1 ATOM 6252 C CD2 . LEU D 4 130 ? 13.378 -21.245 33.410 1.00 65.22 ? 131 LEU L CD2 1 ATOM 6253 N N . GLN D 4 131 ? 9.515 -20.510 36.961 1.00 107.53 ? 132 GLN L N 1 ATOM 6254 C CA . GLN D 4 131 ? 9.354 -20.345 38.401 1.00 107.53 ? 132 GLN L CA 1 ATOM 6255 C C . GLN D 4 131 ? 7.900 -20.638 38.698 1.00 107.53 ? 132 GLN L C 1 ATOM 6256 O O . GLN D 4 131 ? 7.596 -21.113 39.790 1.00 107.53 ? 132 GLN L O 1 ATOM 6257 C CB . GLN D 4 131 ? 9.728 -18.943 38.831 1.00 104.64 ? 132 GLN L CB 1 ATOM 6258 C CG . GLN D 4 131 ? 9.638 -18.722 40.300 1.00 104.64 ? 132 GLN L CG 1 ATOM 6259 C CD . GLN D 4 131 ? 10.743 -19.491 41.037 1.00 104.64 ? 132 GLN L CD 1 ATOM 6260 O OE1 . GLN D 4 131 ? 11.929 -19.149 40.945 1.00 104.64 ? 132 GLN L OE1 1 ATOM 6261 N NE2 . GLN D 4 131 ? 10.351 -20.529 41.782 1.00 104.64 ? 132 GLN L NE2 1 ATOM 6262 N N . ALA D 4 132 ? 7.009 -20.172 37.822 1.00 66.24 ? 133 ALA L N 1 ATOM 6263 C CA . ALA D 4 132 ? 5.540 -20.379 37.933 1.00 66.24 ? 133 ALA L CA 1 ATOM 6264 C C . ALA D 4 132 ? 5.067 -21.743 37.357 1.00 66.24 ? 133 ALA L C 1 ATOM 6265 O O . ALA D 4 132 ? 3.873 -22.075 37.410 1.00 66.24 ? 133 ALA L O 1 ATOM 6266 C CB . ALA D 4 132 ? 4.798 -19.237 37.240 1.00 76.34 ? 133 ALA L CB 1 ATOM 6267 N N . ASN D 4 133 ? 6.050 -22.555 36.961 1.00 137.04 ? 134 ASN L N 1 ATOM 6268 C CA . ASN D 4 133 ? 5.919 -23.862 36.301 1.00 137.04 ? 134 ASN L CA 1 ATOM 6269 C C . ASN D 4 133 ? 5.192 -23.949 34.937 1.00 137.04 ? 134 ASN L C 1 ATOM 6270 O O . ASN D 4 133 ? 4.442 -24.892 34.649 1.00 137.04 ? 134 ASN L O 1 ATOM 6271 C CB . ASN D 4 133 ? 5.217 -24.799 37.304 1.00 139.83 ? 134 ASN L CB 1 ATOM 6272 C CG . ASN D 4 133 ? 5.328 -26.269 36.947 1.00 139.83 ? 134 ASN L CG 1 ATOM 6273 O OD1 . ASN D 4 133 ? 6.294 -26.693 36.339 1.00 139.83 ? 134 ASN L OD1 1 ATOM 6274 N ND2 . ASN D 4 133 ? 4.333 -27.060 37.352 1.00 139.83 ? 134 ASN L ND2 1 ATOM 6275 N N . LYS D 4 134 ? 5.441 -22.959 34.081 1.00 96.31 ? 135 LYS L N 1 ATOM 6276 C CA . LYS D 4 134 ? 4.952 -23.003 32.717 1.00 96.31 ? 135 LYS L CA 1 ATOM 6277 C C . LYS D 4 134 ? 6.137 -22.450 31.865 1.00 96.31 ? 135 LYS L C 1 ATOM 6278 O O . LYS D 4 134 ? 6.929 -21.652 32.348 1.00 96.31 ? 135 LYS L O 1 ATOM 6279 C CB . LYS D 4 134 ? 3.723 -22.105 32.494 1.00 108.55 ? 135 LYS L CB 1 ATOM 6280 C CG . LYS D 4 134 ? 2.436 -22.568 33.157 1.00 108.55 ? 135 LYS L CG 1 ATOM 6281 C CD . LYS D 4 134 ? 1.230 -21.600 32.868 1.00 108.55 ? 135 LYS L CD 1 ATOM 6282 C CE . LYS D 4 134 ? 1.274 -20.123 33.341 1.00 108.55 ? 135 LYS L CE 1 ATOM 6283 N NZ . LYS D 4 134 ? 2.358 -19.302 32.693 1.00 108.55 ? 135 LYS L NZ 1 ATOM 6284 N N . ALA D 4 135 ? 6.307 -22.868 30.622 1.00 82.54 ? 136 ALA L N 1 ATOM 6285 C CA . ALA D 4 135 ? 7.343 -22.220 29.848 1.00 82.54 ? 136 ALA L CA 1 ATOM 6286 C C . ALA D 4 135 ? 6.790 -21.983 28.444 1.00 82.54 ? 136 ALA L C 1 ATOM 6287 O O . ALA D 4 135 ? 6.402 -22.928 27.740 1.00 82.54 ? 136 ALA L O 1 ATOM 6288 C CB . ALA D 4 135 ? 8.571 -23.091 29.796 1.00 88.48 ? 136 ALA L CB 1 ATOM 6289 N N . THR D 4 136 ? 6.868 -20.728 28.005 1.00 107.76 ? 137 THR L N 1 ATOM 6290 C CA . THR D 4 136 ? 6.376 -20.322 26.696 1.00 107.76 ? 137 THR L CA 1 ATOM 6291 C C . THR D 4 136 ? 7.524 -19.760 25.906 1.00 107.76 ? 137 THR L C 1 ATOM 6292 O O . THR D 4 136 ? 8.146 -18.820 26.371 1.00 107.76 ? 137 THR L O 1 ATOM 6293 C CB . THR D 4 136 ? 5.283 -19.220 26.842 1.00 125.28 ? 137 THR L CB 1 ATOM 6294 O OG1 . THR D 4 136 ? 4.179 -19.709 27.609 1.00 125.28 ? 137 THR L OG1 1 ATOM 6295 C CG2 . THR D 4 136 ? 4.789 -18.789 25.519 1.00 125.28 ? 137 THR L CG2 1 ATOM 6296 N N . LEU D 4 137 ? 7.715 -20.222 24.671 1.00 111.26 ? 138 LEU L N 1 ATOM 6297 C CA . LEU D 4 137 ? 8.819 -19.748 23.821 1.00 111.26 ? 138 LEU L CA 1 ATOM 6298 C C . LEU D 4 137 ? 8.099 -18.743 23.005 1.00 111.26 ? 138 LEU L C 1 ATOM 6299 O O . LEU D 4 137 ? 6.960 -18.934 22.665 1.00 111.26 ? 138 LEU L O 1 ATOM 6300 C CB . LEU D 4 137 ? 9.376 -20.833 22.912 1.00 87.66 ? 138 LEU L CB 1 ATOM 6301 C CG . LEU D 4 137 ? 10.155 -21.940 23.591 1.00 87.66 ? 138 LEU L CG 1 ATOM 6302 C CD1 . LEU D 4 137 ? 9.186 -22.718 24.412 1.00 87.66 ? 138 LEU L CD1 1 ATOM 6303 C CD2 . LEU D 4 137 ? 10.770 -22.864 22.565 1.00 87.66 ? 138 LEU L CD2 1 ATOM 6304 N N . VAL D 4 138 ? 8.688 -17.623 22.723 1.00 95.21 ? 139 VAL L N 1 ATOM 6305 C CA . VAL D 4 138 ? 7.848 -16.744 22.016 1.00 95.21 ? 139 VAL L CA 1 ATOM 6306 C C . VAL D 4 138 ? 8.612 -16.580 20.725 1.00 95.21 ? 139 VAL L C 1 ATOM 6307 O O . VAL D 4 138 ? 9.813 -16.382 20.776 1.00 95.21 ? 139 VAL L O 1 ATOM 6308 C CB . VAL D 4 138 ? 7.799 -15.443 22.769 1.00 75.52 ? 139 VAL L CB 1 ATOM 6309 C CG1 . VAL D 4 138 ? 6.912 -14.464 22.055 1.00 75.52 ? 139 VAL L CG1 1 ATOM 6310 C CG2 . VAL D 4 138 ? 7.456 -15.693 24.212 1.00 75.52 ? 139 VAL L CG2 1 ATOM 6311 N N . CYS D 4 139 ? 7.954 -16.750 19.560 1.00 76.49 ? 140 CYS L N 1 ATOM 6312 C CA . CYS D 4 139 ? 8.617 -16.522 18.247 1.00 76.49 ? 140 CYS L CA 1 ATOM 6313 C C . CYS D 4 139 ? 8.005 -15.273 17.637 1.00 76.49 ? 140 CYS L C 1 ATOM 6314 O O . CYS D 4 139 ? 6.783 -15.138 17.607 1.00 76.49 ? 140 CYS L O 1 ATOM 6315 C CB . CYS D 4 139 ? 8.444 -17.694 17.256 1.00 70.45 ? 140 CYS L CB 1 ATOM 6316 S SG . CYS D 4 139 ? 9.711 -17.678 15.904 1.00 70.45 ? 140 CYS L SG 1 ATOM 6317 N N . LEU D 4 140 ? 8.868 -14.347 17.209 1.00 60.31 ? 141 LEU L N 1 ATOM 6318 C CA . LEU D 4 140 ? 8.428 -13.118 16.564 1.00 60.31 ? 141 LEU L CA 1 ATOM 6319 C C . LEU D 4 140 ? 8.893 -13.277 15.139 1.00 60.31 ? 141 LEU L C 1 ATOM 6320 O O . LEU D 4 140 ? 10.092 -13.578 14.921 1.00 60.31 ? 141 LEU L O 1 ATOM 6321 C CB . LEU D 4 140 ? 9.038 -11.857 17.161 1.00 48.02 ? 141 LEU L CB 1 ATOM 6322 C CG . LEU D 4 140 ? 8.415 -11.713 18.549 1.00 48.02 ? 141 LEU L CG 1 ATOM 6323 C CD1 . LEU D 4 140 ? 9.222 -10.604 19.215 1.00 48.02 ? 141 LEU L CD1 1 ATOM 6324 C CD2 . LEU D 4 140 ? 6.941 -11.464 18.614 1.00 48.02 ? 141 LEU L CD2 1 ATOM 6325 N N . ILE D 4 141 ? 7.960 -13.028 14.193 1.00 113.73 ? 142 ILE L N 1 ATOM 6326 C CA . ILE D 4 141 ? 8.183 -13.173 12.767 1.00 113.73 ? 142 ILE L CA 1 ATOM 6327 C C . ILE D 4 141 ? 7.875 -11.667 12.446 1.00 113.73 ? 142 ILE L C 1 ATOM 6328 O O . ILE D 4 141 ? 6.775 -11.213 12.707 1.00 113.73 ? 142 ILE L O 1 ATOM 6329 C CB . ILE D 4 141 ? 7.013 -13.956 12.163 1.00 74.86 ? 142 ILE L CB 1 ATOM 6330 C CG1 . ILE D 4 141 ? 6.839 -15.367 12.754 1.00 74.86 ? 142 ILE L CG1 1 ATOM 6331 C CG2 . ILE D 4 141 ? 7.358 -14.303 10.711 1.00 74.86 ? 142 ILE L CG2 1 ATOM 6332 C CD1 . ILE D 4 141 ? 7.962 -16.223 12.821 1.00 74.86 ? 142 ILE L CD1 1 ATOM 6333 N N . SER D 4 142 ? 8.784 -10.886 11.881 1.00 71.20 ? 143 SER L N 1 ATOM 6334 C CA . SER D 4 142 ? 8.458 -9.476 11.592 1.00 71.20 ? 143 SER L CA 1 ATOM 6335 C C . SER D 4 142 ? 8.949 -8.795 10.285 1.00 71.20 ? 143 SER L C 1 ATOM 6336 O O . SER D 4 142 ? 9.916 -9.183 9.674 1.00 71.20 ? 143 SER L O 1 ATOM 6337 C CB . SER D 4 142 ? 8.899 -8.616 12.758 1.00 89.57 ? 143 SER L CB 1 ATOM 6338 O OG . SER D 4 142 ? 10.307 -8.601 12.794 1.00 89.57 ? 143 SER L OG 1 ATOM 6339 N N . ASP D 4 143 ? 8.293 -7.719 9.915 1.00 62.92 ? 144 ASP L N 1 ATOM 6340 C CA . ASP D 4 143 ? 8.633 -6.946 8.738 1.00 62.92 ? 144 ASP L CA 1 ATOM 6341 C C . ASP D 4 143 ? 8.619 -7.563 7.316 1.00 62.92 ? 144 ASP L C 1 ATOM 6342 O O . ASP D 4 143 ? 9.387 -7.190 6.434 1.00 62.92 ? 144 ASP L O 1 ATOM 6343 C CB . ASP D 4 143 ? 9.939 -6.290 9.052 1.00 95.79 ? 144 ASP L CB 1 ATOM 6344 C CG . ASP D 4 143 ? 9.765 -5.241 10.077 1.00 95.79 ? 144 ASP L CG 1 ATOM 6345 O OD1 . ASP D 4 143 ? 10.740 -4.860 10.719 1.00 95.79 ? 144 ASP L OD1 1 ATOM 6346 O OD2 . ASP D 4 143 ? 8.638 -4.761 10.248 1.00 95.79 ? 144 ASP L OD2 1 ATOM 6347 N N . PHE D 4 144 ? 7.631 -8.392 7.040 1.00 52.36 ? 145 PHE L N 1 ATOM 6348 C CA . PHE D 4 144 ? 7.588 -9.083 5.786 1.00 52.36 ? 145 PHE L CA 1 ATOM 6349 C C . PHE D 4 144 ? 6.252 -8.927 5.168 1.00 52.36 ? 145 PHE L C 1 ATOM 6350 O O . PHE D 4 144 ? 5.250 -8.657 5.841 1.00 52.36 ? 145 PHE L O 1 ATOM 6351 C CB . PHE D 4 144 ? 7.765 -10.558 6.028 1.00 89.69 ? 145 PHE L CB 1 ATOM 6352 C CG . PHE D 4 144 ? 6.638 -11.184 6.838 1.00 89.69 ? 145 PHE L CG 1 ATOM 6353 C CD1 . PHE D 4 144 ? 5.510 -11.719 6.219 1.00 89.69 ? 145 PHE L CD1 1 ATOM 6354 C CD2 . PHE D 4 144 ? 6.714 -11.262 8.217 1.00 89.69 ? 145 PHE L CD2 1 ATOM 6355 C CE1 . PHE D 4 144 ? 4.488 -12.318 6.965 1.00 89.69 ? 145 PHE L CE1 1 ATOM 6356 C CE2 . PHE D 4 144 ? 5.689 -11.863 8.950 1.00 89.69 ? 145 PHE L CE2 1 ATOM 6357 C CZ . PHE D 4 144 ? 4.584 -12.387 8.315 1.00 89.69 ? 145 PHE L CZ 1 ATOM 6358 N N . TYR D 4 145 ? 6.290 -9.069 3.851 1.00 58.01 ? 146 TYR L N 1 ATOM 6359 C CA . TYR D 4 145 ? 5.194 -8.944 2.900 1.00 58.01 ? 146 TYR L CA 1 ATOM 6360 C C . TYR D 4 145 ? 5.374 -10.033 1.876 1.00 58.01 ? 146 TYR L C 1 ATOM 6361 O O . TYR D 4 145 ? 6.428 -10.489 1.691 1.00 58.01 ? 146 TYR L O 1 ATOM 6362 C CB . TYR D 4 145 ? 5.308 -7.572 2.269 1.00 59.62 ? 146 TYR L CB 1 ATOM 6363 C CG . TYR D 4 145 ? 4.233 -7.223 1.366 1.00 59.62 ? 146 TYR L CG 1 ATOM 6364 C CD1 . TYR D 4 145 ? 3.067 -6.736 1.854 1.00 59.62 ? 146 TYR L CD1 1 ATOM 6365 C CD2 . TYR D 4 145 ? 4.351 -7.449 0.054 1.00 59.62 ? 146 TYR L CD2 1 ATOM 6366 C CE1 . TYR D 4 145 ? 2.026 -6.487 1.070 1.00 59.62 ? 146 TYR L CE1 1 ATOM 6367 C CE2 . TYR D 4 145 ? 3.313 -7.215 -0.753 1.00 59.62 ? 146 TYR L CE2 1 ATOM 6368 C CZ . TYR D 4 145 ? 2.109 -6.728 -0.240 1.00 59.62 ? 146 TYR L CZ 1 ATOM 6369 O OH . TYR D 4 145 ? 0.935 -6.530 -1.005 1.00 59.62 ? 146 TYR L OH 1 ATOM 6370 N N . PRO D 4 146 ? 4.346 -10.499 1.231 1.00 49.26 ? 147 PRO L N 1 ATOM 6371 C CA . PRO D 4 146 ? 2.923 -10.226 1.234 1.00 49.26 ? 147 PRO L CA 1 ATOM 6372 C C . PRO D 4 146 ? 2.607 -10.745 2.590 1.00 49.26 ? 147 PRO L C 1 ATOM 6373 O O . PRO D 4 146 ? 3.491 -11.401 3.119 1.00 49.26 ? 147 PRO L O 1 ATOM 6374 C CB . PRO D 4 146 ? 2.406 -11.152 0.157 1.00 59.09 ? 147 PRO L CB 1 ATOM 6375 C CG . PRO D 4 146 ? 3.537 -11.324 -0.766 1.00 59.09 ? 147 PRO L CG 1 ATOM 6376 C CD . PRO D 4 146 ? 4.660 -11.510 0.226 1.00 59.09 ? 147 PRO L CD 1 ATOM 6377 N N . GLY D 4 147 ? 1.402 -10.507 3.132 1.00 79.14 ? 148 GLY L N 1 ATOM 6378 C CA . GLY D 4 147 ? 1.073 -10.944 4.480 1.00 79.14 ? 148 GLY L CA 1 ATOM 6379 C C . GLY D 4 147 ? 1.129 -12.418 4.801 1.00 79.14 ? 148 GLY L C 1 ATOM 6380 O O . GLY D 4 147 ? 1.634 -12.779 5.816 1.00 79.14 ? 148 GLY L O 1 ATOM 6381 N N . ALA D 4 148 ? 0.691 -13.301 3.933 1.00 79.29 ? 149 ALA L N 1 ATOM 6382 C CA . ALA D 4 148 ? 0.682 -14.708 4.299 1.00 79.29 ? 149 ALA L CA 1 ATOM 6383 C C . ALA D 4 148 ? 2.015 -15.329 4.573 1.00 79.29 ? 149 ALA L C 1 ATOM 6384 O O . ALA D 4 148 ? 2.938 -15.262 3.763 1.00 79.29 ? 149 ALA L O 1 ATOM 6385 C CB . ALA D 4 148 ? -0.036 -15.515 3.203 1.00 154.65 ? 149 ALA L CB 1 ATOM 6386 N N . VAL D 4 149 ? 2.069 -15.998 5.714 1.00 83.88 ? 150 VAL L N 1 ATOM 6387 C CA . VAL D 4 149 ? 3.255 -16.680 6.198 1.00 83.88 ? 150 VAL L CA 1 ATOM 6388 C C . VAL D 4 149 ? 2.877 -17.958 6.897 1.00 83.88 ? 150 VAL L C 1 ATOM 6389 O O . VAL D 4 149 ? 1.776 -18.051 7.394 1.00 83.88 ? 150 VAL L O 1 ATOM 6390 C CB . VAL D 4 149 ? 4.082 -15.803 7.113 1.00 69.66 ? 150 VAL L CB 1 ATOM 6391 C CG1 . VAL D 4 149 ? 3.311 -15.387 8.317 1.00 69.66 ? 150 VAL L CG1 1 ATOM 6392 C CG2 . VAL D 4 149 ? 5.306 -16.540 7.489 1.00 69.66 ? 150 VAL L CG2 1 ATOM 6393 N N . THR D 4 150 ? 3.730 -18.968 6.871 1.00 81.12 ? 151 THR L N 1 ATOM 6394 C CA . THR D 4 150 ? 3.449 -20.230 7.577 1.00 81.12 ? 151 THR L CA 1 ATOM 6395 C C . THR D 4 150 ? 4.645 -20.643 8.444 1.00 81.12 ? 151 THR L C 1 ATOM 6396 O O . THR D 4 150 ? 5.783 -20.521 7.980 1.00 81.12 ? 151 THR L O 1 ATOM 6397 C CB . THR D 4 150 ? 3.185 -21.390 6.555 1.00 97.79 ? 151 THR L CB 1 ATOM 6398 O OG1 . THR D 4 150 ? 2.911 -22.620 7.248 1.00 97.79 ? 151 THR L OG1 1 ATOM 6399 C CG2 . THR D 4 150 ? 4.377 -21.586 5.647 1.00 97.79 ? 151 THR L CG2 1 ATOM 6400 N N . VAL D 4 151 ? 4.390 -21.160 9.660 1.00 90.99 ? 152 VAL L N 1 ATOM 6401 C CA . VAL D 4 151 ? 5.453 -21.590 10.609 1.00 90.99 ? 152 VAL L CA 1 ATOM 6402 C C . VAL D 4 151 ? 5.343 -22.969 11.229 1.00 90.99 ? 152 VAL L C 1 ATOM 6403 O O . VAL D 4 151 ? 4.281 -23.549 11.181 1.00 90.99 ? 152 VAL L O 1 ATOM 6404 C CB . VAL D 4 151 ? 5.627 -20.626 11.814 1.00 73.47 ? 152 VAL L CB 1 ATOM 6405 C CG1 . VAL D 4 151 ? 5.999 -19.228 11.351 1.00 73.47 ? 152 VAL L CG1 1 ATOM 6406 C CG2 . VAL D 4 151 ? 4.331 -20.570 12.603 1.00 73.47 ? 152 VAL L CG2 1 ATOM 6407 N N . ALA D 4 152 ? 6.452 -23.520 11.739 1.00 102.14 ? 153 ALA L N 1 ATOM 6408 C CA . ALA D 4 152 ? 6.415 -24.819 12.432 1.00 102.14 ? 153 ALA L CA 1 ATOM 6409 C C . ALA D 4 152 ? 7.541 -24.889 13.484 1.00 102.14 ? 153 ALA L C 1 ATOM 6410 O O . ALA D 4 152 ? 8.578 -24.234 13.282 1.00 102.14 ? 153 ALA L O 1 ATOM 6411 C CB . ALA D 4 152 ? 6.556 -25.955 11.413 1.00 65.17 ? 153 ALA L CB 1 ATOM 6412 N N . TRP D 4 153 ? 7.424 -25.757 14.513 1.00 86.68 ? 154 TRP L N 1 ATOM 6413 C CA . TRP D 4 153 ? 8.476 -25.822 15.556 1.00 86.68 ? 154 TRP L CA 1 ATOM 6414 C C . TRP D 4 153 ? 9.085 -27.195 15.617 1.00 86.68 ? 154 TRP L C 1 ATOM 6415 O O . TRP D 4 153 ? 8.390 -28.217 15.581 1.00 86.68 ? 154 TRP L O 1 ATOM 6416 C CB . TRP D 4 153 ? 7.912 -25.503 16.954 1.00 93.44 ? 154 TRP L CB 1 ATOM 6417 C CG . TRP D 4 153 ? 7.477 -24.060 17.257 1.00 93.44 ? 154 TRP L CG 1 ATOM 6418 C CD1 . TRP D 4 153 ? 6.203 -23.497 17.127 1.00 93.44 ? 154 TRP L CD1 1 ATOM 6419 C CD2 . TRP D 4 153 ? 8.302 -23.043 17.836 1.00 93.44 ? 154 TRP L CD2 1 ATOM 6420 N NE1 . TRP D 4 153 ? 6.226 -22.202 17.592 1.00 93.44 ? 154 TRP L NE1 1 ATOM 6421 C CE2 . TRP D 4 153 ? 7.501 -21.908 18.033 1.00 93.44 ? 154 TRP L CE2 1 ATOM 6422 C CE3 . TRP D 4 153 ? 9.644 -22.986 18.214 1.00 93.44 ? 154 TRP L CE3 1 ATOM 6423 C CZ2 . TRP D 4 153 ? 8.023 -20.732 18.600 1.00 93.44 ? 154 TRP L CZ2 1 ATOM 6424 C CZ3 . TRP D 4 153 ? 10.147 -21.817 18.777 1.00 93.44 ? 154 TRP L CZ3 1 ATOM 6425 C CH2 . TRP D 4 153 ? 9.349 -20.718 18.965 1.00 93.44 ? 154 TRP L CH2 1 ATOM 6426 N N . LYS D 4 154 ? 10.400 -27.199 15.799 1.00 113.66 ? 155 LYS L N 1 ATOM 6427 C CA . LYS D 4 154 ? 11.140 -28.448 15.777 1.00 113.66 ? 155 LYS L CA 1 ATOM 6428 C C . LYS D 4 154 ? 12.242 -28.635 16.871 1.00 113.66 ? 155 LYS L C 1 ATOM 6429 O O . LYS D 4 154 ? 13.065 -27.743 17.089 1.00 113.66 ? 155 LYS L O 1 ATOM 6430 C CB . LYS D 4 154 ? 11.633 -28.537 14.322 1.00 137.06 ? 155 LYS L CB 1 ATOM 6431 C CG . LYS D 4 154 ? 12.433 -29.706 13.835 1.00 137.06 ? 155 LYS L CG 1 ATOM 6432 C CD . LYS D 4 154 ? 12.536 -29.590 12.269 1.00 137.06 ? 155 LYS L CD 1 ATOM 6433 C CE . LYS D 4 154 ? 13.344 -28.349 11.814 1.00 137.06 ? 155 LYS L CE 1 ATOM 6434 N NZ . LYS D 4 154 ? 13.505 -28.199 10.336 1.00 137.06 ? 155 LYS L NZ 1 ATOM 6435 N N . ALA D 4 155 ? 12.222 -29.774 17.573 1.00 97.76 ? 156 ALA L N 1 ATOM 6436 C CA . ALA D 4 155 ? 13.210 -30.086 18.611 1.00 97.76 ? 156 ALA L CA 1 ATOM 6437 C C . ALA D 4 155 ? 14.282 -31.039 18.036 1.00 97.76 ? 156 ALA L C 1 ATOM 6438 O O . ALA D 4 155 ? 13.912 -32.128 17.601 1.00 97.76 ? 156 ALA L O 1 ATOM 6439 C CB . ALA D 4 155 ? 12.507 -30.736 19.754 1.00 96.40 ? 156 ALA L CB 1 ATOM 6440 N N . ASP D 4 156 ? 15.575 -30.668 18.015 1.00 163.85 ? 157 ASP L N 1 ATOM 6441 C CA . ASP D 4 156 ? 16.568 -31.569 17.394 1.00 163.85 ? 157 ASP L CA 1 ATOM 6442 C C . ASP D 4 156 ? 16.150 -32.017 16.030 1.00 163.85 ? 157 ASP L C 1 ATOM 6443 O O . ASP D 4 156 ? 16.243 -33.185 15.654 1.00 163.85 ? 157 ASP L O 1 ATOM 6444 C CB . ASP D 4 156 ? 17.076 -32.734 18.273 1.00 109.68 ? 157 ASP L CB 1 ATOM 6445 C CG . ASP D 4 156 ? 17.968 -32.271 19.417 1.00 109.68 ? 157 ASP L CG 1 ATOM 6446 O OD1 . ASP D 4 156 ? 18.081 -32.977 20.458 1.00 109.68 ? 157 ASP L OD1 1 ATOM 6447 O OD2 . ASP D 4 156 ? 18.666 -31.237 19.212 1.00 109.68 ? 157 ASP L OD2 1 ATOM 6448 N N . SER D 4 157 ? 15.593 -31.043 15.336 1.00 133.29 ? 158 SER L N 1 ATOM 6449 C CA . SER D 4 157 ? 15.100 -31.155 13.977 1.00 133.29 ? 158 SER L CA 1 ATOM 6450 C C . SER D 4 157 ? 14.181 -32.376 13.827 1.00 133.29 ? 158 SER L C 1 ATOM 6451 O O . SER D 4 157 ? 14.215 -33.097 12.819 1.00 133.29 ? 158 SER L O 1 ATOM 6452 C CB . SER D 4 157 ? 16.302 -31.228 13.012 1.00 105.31 ? 158 SER L CB 1 ATOM 6453 O OG . SER D 4 157 ? 17.363 -30.360 13.433 1.00 105.31 ? 158 SER L OG 1 ATOM 6454 N N . SER D 4 158 ? 13.377 -32.593 14.866 1.00 131.64 ? 159 SER L N 1 ATOM 6455 C CA . SER D 4 158 ? 12.342 -33.618 14.917 1.00 131.64 ? 159 SER L CA 1 ATOM 6456 C C . SER D 4 158 ? 11.002 -32.883 15.146 1.00 131.64 ? 159 SER L C 1 ATOM 6457 O O . SER D 4 158 ? 10.794 -32.347 16.242 1.00 131.64 ? 159 SER L O 1 ATOM 6458 C CB . SER D 4 158 ? 12.654 -34.647 15.999 1.00 108.78 ? 159 SER L CB 1 ATOM 6459 O OG . SER D 4 158 ? 11.669 -35.664 15.995 1.00 108.78 ? 159 SER L OG 1 ATOM 6460 N N . PRO D 4 159 ? 10.095 -32.831 14.158 1.00 108.74 ? 160 PRO L N 1 ATOM 6461 C CA . PRO D 4 159 ? 8.798 -32.126 14.290 1.00 108.74 ? 160 PRO L CA 1 ATOM 6462 C C . PRO D 4 159 ? 7.948 -32.300 15.548 1.00 108.74 ? 160 PRO L C 1 ATOM 6463 O O . PRO D 4 159 ? 7.773 -33.421 16.019 1.00 108.74 ? 160 PRO L O 1 ATOM 6464 C CB . PRO D 4 159 ? 8.025 -32.598 13.057 1.00 135.62 ? 160 PRO L CB 1 ATOM 6465 C CG . PRO D 4 159 ? 8.410 -34.036 13.013 1.00 135.62 ? 160 PRO L CG 1 ATOM 6466 C CD . PRO D 4 159 ? 9.950 -33.954 13.213 1.00 135.62 ? 160 PRO L CD 1 ATOM 6467 N N . VAL D 4 160 ? 7.473 -31.196 16.127 1.00 118.62 ? 161 VAL L N 1 ATOM 6468 C CA . VAL D 4 160 ? 6.537 -31.375 17.226 1.00 118.62 ? 161 VAL L CA 1 ATOM 6469 C C . VAL D 4 160 ? 5.264 -30.697 16.683 1.00 118.62 ? 161 VAL L C 1 ATOM 6470 O O . VAL D 4 160 ? 5.329 -29.492 16.424 1.00 118.62 ? 161 VAL L O 1 ATOM 6471 C CB . VAL D 4 160 ? 6.966 -30.513 18.395 1.00 80.33 ? 161 VAL L CB 1 ATOM 6472 C CG1 . VAL D 4 160 ? 5.986 -30.686 19.578 1.00 80.33 ? 161 VAL L CG1 1 ATOM 6473 C CG2 . VAL D 4 160 ? 8.386 -30.787 18.711 1.00 80.33 ? 161 VAL L CG2 1 ATOM 6474 N N . LYS D 4 161 ? 4.123 -31.401 16.540 1.00 140.10 ? 162 LYS L N 1 ATOM 6475 C CA . LYS D 4 161 ? 2.873 -30.731 16.105 1.00 140.10 ? 162 LYS L CA 1 ATOM 6476 C C . LYS D 4 161 ? 1.975 -30.443 17.265 1.00 140.10 ? 162 LYS L C 1 ATOM 6477 O O . LYS D 4 161 ? 0.877 -29.909 17.090 1.00 140.10 ? 162 LYS L O 1 ATOM 6478 C CB . LYS D 4 161 ? 2.048 -31.462 15.035 1.00 101.99 ? 162 LYS L CB 1 ATOM 6479 C CG . LYS D 4 161 ? 1.505 -32.837 15.370 1.00 101.99 ? 162 LYS L CG 1 ATOM 6480 C CD . LYS D 4 161 ? 0.621 -33.319 14.197 1.00 101.99 ? 162 LYS L CD 1 ATOM 6481 C CE . LYS D 4 161 ? 1.445 -33.701 12.919 1.00 101.99 ? 162 LYS L CE 1 ATOM 6482 N NZ . LYS D 4 161 ? 2.442 -34.828 13.050 1.00 101.99 ? 162 LYS L NZ 1 ATOM 6483 N N . ALA D 4 162 ? 2.449 -30.832 18.446 1.00 116.24 ? 163 ALA L N 1 ATOM 6484 C CA . ALA D 4 162 ? 1.683 -30.721 19.680 1.00 116.24 ? 163 ALA L CA 1 ATOM 6485 C C . ALA D 4 162 ? 2.082 -29.470 20.437 1.00 116.24 ? 163 ALA L C 1 ATOM 6486 O O . ALA D 4 162 ? 3.261 -29.124 20.475 1.00 116.24 ? 163 ALA L O 1 ATOM 6487 C CB . ALA D 4 162 ? 1.926 -31.956 20.535 1.00 85.21 ? 163 ALA L CB 1 ATOM 6488 N N . GLY D 4 163 ? 1.100 -28.784 21.021 1.00 87.40 ? 164 GLY L N 1 ATOM 6489 C CA . GLY D 4 163 ? 1.414 -27.569 21.740 1.00 87.40 ? 164 GLY L CA 1 ATOM 6490 C C . GLY D 4 163 ? 1.786 -26.331 20.938 1.00 87.40 ? 164 GLY L C 1 ATOM 6491 O O . GLY D 4 163 ? 2.602 -25.538 21.402 1.00 87.40 ? 164 GLY L O 1 ATOM 6492 N N . VAL D 4 164 ? 1.271 -26.177 19.715 1.00 123.21 ? 165 VAL L N 1 ATOM 6493 C CA . VAL D 4 164 ? 1.563 -24.966 18.952 1.00 123.21 ? 165 VAL L CA 1 ATOM 6494 C C . VAL D 4 164 ? 0.275 -24.205 18.618 1.00 123.21 ? 165 VAL L C 1 ATOM 6495 O O . VAL D 4 164 ? -0.670 -24.811 18.154 1.00 123.21 ? 165 VAL L O 1 ATOM 6496 C CB . VAL D 4 164 ? 2.257 -25.332 17.615 1.00 63.22 ? 165 VAL L CB 1 ATOM 6497 C CG1 . VAL D 4 164 ? 2.547 -24.072 16.839 1.00 63.22 ? 165 VAL L CG1 1 ATOM 6498 C CG2 . VAL D 4 164 ? 3.577 -26.032 17.862 1.00 63.22 ? 165 VAL L CG2 1 ATOM 6499 N N . GLU D 4 165 ? 0.237 -22.894 18.900 1.00 78.00 ? 166 GLU L N 1 ATOM 6500 C CA . GLU D 4 165 ? -0.875 -21.978 18.553 1.00 78.00 ? 166 GLU L CA 1 ATOM 6501 C C . GLU D 4 165 ? -0.260 -20.886 17.636 1.00 78.00 ? 166 GLU L C 1 ATOM 6502 O O . GLU D 4 165 ? 0.909 -20.596 17.791 1.00 78.00 ? 166 GLU L O 1 ATOM 6503 C CB . GLU D 4 165 ? -1.448 -21.289 19.772 1.00 108.18 ? 166 GLU L CB 1 ATOM 6504 C CG . GLU D 4 165 ? -2.162 -22.191 20.706 1.00 108.18 ? 166 GLU L CG 1 ATOM 6505 C CD . GLU D 4 165 ? -3.420 -22.778 20.143 1.00 108.18 ? 166 GLU L CD 1 ATOM 6506 O OE1 . GLU D 4 165 ? -3.889 -23.818 20.673 1.00 108.18 ? 166 GLU L OE1 1 ATOM 6507 O OE2 . GLU D 4 165 ? -3.932 -22.222 19.154 1.00 108.18 ? 166 GLU L OE2 1 ATOM 6508 N N . THR D 4 166 ? -0.903 -20.413 16.574 1.00 69.70 ? 167 THR L N 1 ATOM 6509 C CA . THR D 4 166 ? -0.288 -19.280 15.822 1.00 69.70 ? 167 THR L CA 1 ATOM 6510 C C . THR D 4 166 ? -1.094 -18.040 15.472 1.00 69.70 ? 167 THR L C 1 ATOM 6511 O O . THR D 4 166 ? -2.209 -18.194 15.049 1.00 69.70 ? 167 THR L O 1 ATOM 6512 C CB . THR D 4 166 ? 0.500 -19.767 14.594 1.00 100.12 ? 167 THR L CB 1 ATOM 6513 O OG1 . THR D 4 166 ? 1.690 -20.456 15.035 1.00 100.12 ? 167 THR L OG1 1 ATOM 6514 C CG2 . THR D 4 166 ? 0.864 -18.619 13.720 1.00 100.12 ? 167 THR L CG2 1 ATOM 6515 N N . THR D 4 167 ? -0.556 -16.822 15.559 1.00 66.92 ? 168 THR L N 1 ATOM 6516 C CA . THR D 4 167 ? -1.426 -15.697 15.192 1.00 66.92 ? 168 THR L CA 1 ATOM 6517 C C . THR D 4 167 ? -1.336 -15.543 13.682 1.00 66.92 ? 168 THR L C 1 ATOM 6518 O O . THR D 4 167 ? -0.236 -15.721 13.151 1.00 66.92 ? 168 THR L O 1 ATOM 6519 C CB . THR D 4 167 ? -0.954 -14.356 15.804 1.00 63.86 ? 168 THR L CB 1 ATOM 6520 O OG1 . THR D 4 167 ? 0.434 -14.194 15.566 1.00 63.86 ? 168 THR L OG1 1 ATOM 6521 C CG2 . THR D 4 167 ? -1.221 -14.283 17.247 1.00 63.86 ? 168 THR L CG2 1 ATOM 6522 N N . THR D 4 168 ? -2.469 -15.306 12.982 1.00 72.12 ? 169 THR L N 1 ATOM 6523 C CA . THR D 4 168 ? -2.419 -15.082 11.524 1.00 72.12 ? 169 THR L CA 1 ATOM 6524 C C . THR D 4 168 ? -1.771 -13.746 11.249 1.00 72.12 ? 169 THR L C 1 ATOM 6525 O O . THR D 4 168 ? -1.991 -12.794 12.004 1.00 72.12 ? 169 THR L O 1 ATOM 6526 C CB . THR D 4 168 ? -3.789 -15.143 10.837 1.00 66.77 ? 169 THR L CB 1 ATOM 6527 O OG1 . THR D 4 168 ? -4.646 -14.137 11.383 1.00 66.77 ? 169 THR L OG1 1 ATOM 6528 C CG2 . THR D 4 168 ? -4.429 -16.513 11.028 1.00 66.77 ? 169 THR L CG2 1 ATOM 6529 N N . PRO D 4 169 ? -1.092 -13.624 10.099 1.00 62.80 ? 170 PRO L N 1 ATOM 6530 C CA . PRO D 4 169 ? -0.404 -12.418 9.681 1.00 62.80 ? 170 PRO L CA 1 ATOM 6531 C C . PRO D 4 169 ? -1.115 -11.151 10.136 1.00 62.80 ? 170 PRO L C 1 ATOM 6532 O O . PRO D 4 169 ? -2.307 -11.163 10.324 1.00 62.80 ? 170 PRO L O 1 ATOM 6533 C CB . PRO D 4 169 ? -0.316 -12.633 8.177 1.00 109.69 ? 170 PRO L CB 1 ATOM 6534 C CG . PRO D 4 169 ? 0.079 -14.107 8.120 1.00 109.69 ? 170 PRO L CG 1 ATOM 6535 C CD . PRO D 4 169 ? -0.825 -14.736 9.159 1.00 109.69 ? 170 PRO L CD 1 ATOM 6536 N N . SER D 4 170 ? -0.325 -10.107 10.406 1.00 67.19 ? 171 SER L N 1 ATOM 6537 C CA . SER D 4 170 ? -0.751 -8.766 10.885 1.00 67.19 ? 171 SER L CA 1 ATOM 6538 C C . SER D 4 170 ? -0.226 -7.479 10.229 1.00 67.19 ? 171 SER L C 1 ATOM 6539 O O . SER D 4 170 ? 0.847 -7.469 9.625 1.00 67.19 ? 171 SER L O 1 ATOM 6540 C CB . SER D 4 170 ? -0.517 -8.607 12.370 1.00 40.38 ? 171 SER L CB 1 ATOM 6541 O OG . SER D 4 170 ? -1.306 -9.525 13.041 1.00 40.38 ? 171 SER L OG 1 ATOM 6542 N N . LYS D 4 171 ? -1.004 -6.403 10.262 1.00 69.99 ? 172 LYS L N 1 ATOM 6543 C CA . LYS D 4 171 ? -0.462 -5.143 9.761 1.00 69.99 ? 172 LYS L CA 1 ATOM 6544 C C . LYS D 4 171 ? 0.365 -4.648 10.882 1.00 69.99 ? 172 LYS L C 1 ATOM 6545 O O . LYS D 4 171 ? 0.214 -5.045 12.004 1.00 69.99 ? 172 LYS L O 1 ATOM 6546 C CB . LYS D 4 171 ? -1.500 -4.088 9.337 1.00 119.17 ? 172 LYS L CB 1 ATOM 6547 C CG . LYS D 4 171 ? -2.311 -4.391 8.061 1.00 119.17 ? 172 LYS L CG 1 ATOM 6548 C CD . LYS D 4 171 ? -1.356 -4.358 6.854 1.00 119.17 ? 172 LYS L CD 1 ATOM 6549 C CE . LYS D 4 171 ? -2.092 -4.418 5.548 1.00 119.17 ? 172 LYS L CE 1 ATOM 6550 N NZ . LYS D 4 171 ? -3.056 -3.299 5.424 1.00 119.17 ? 172 LYS L NZ 1 ATOM 6551 N N . GLN D 4 172 ? 1.271 -3.774 10.562 1.00 66.90 ? 173 GLN L N 1 ATOM 6552 C CA . GLN D 4 172 ? 2.257 -3.319 11.486 1.00 66.90 ? 173 GLN L CA 1 ATOM 6553 C C . GLN D 4 172 ? 2.432 -1.768 11.250 1.00 66.90 ? 173 GLN L C 1 ATOM 6554 O O . GLN D 4 172 ? 1.964 -1.208 10.254 1.00 66.90 ? 173 GLN L O 1 ATOM 6555 C CB . GLN D 4 172 ? 3.449 -4.183 11.180 1.00 87.25 ? 173 GLN L CB 1 ATOM 6556 C CG . GLN D 4 172 ? 4.638 -3.950 11.985 1.00 87.25 ? 173 GLN L CG 1 ATOM 6557 C CD . GLN D 4 172 ? 5.711 -4.908 11.594 1.00 87.25 ? 173 GLN L CD 1 ATOM 6558 O OE1 . GLN D 4 172 ? 5.428 -5.846 10.836 1.00 87.25 ? 173 GLN L OE1 1 ATOM 6559 N NE2 . GLN D 4 172 ? 6.947 -4.700 12.100 1.00 87.25 ? 173 GLN L NE2 1 ATOM 6560 N N . SER D 4 173 ? 3.012 -1.037 12.177 1.00 105.89 ? 174 SER L N 1 ATOM 6561 C CA . SER D 4 173 ? 3.122 0.423 12.047 1.00 105.89 ? 174 SER L CA 1 ATOM 6562 C C . SER D 4 173 ? 3.688 0.968 10.707 1.00 105.89 ? 174 SER L C 1 ATOM 6563 O O . SER D 4 173 ? 3.383 2.100 10.345 1.00 105.89 ? 174 SER L O 1 ATOM 6564 C CB . SER D 4 173 ? 3.946 0.973 13.217 1.00 93.66 ? 174 SER L CB 1 ATOM 6565 O OG . SER D 4 173 ? 5.328 0.594 13.105 1.00 93.66 ? 174 SER L OG 1 ATOM 6566 N N . ASN D 4 174 ? 4.569 0.212 10.036 1.00 125.40 ? 175 ASN L N 1 ATOM 6567 C CA . ASN D 4 174 ? 5.242 0.565 8.735 1.00 125.40 ? 175 ASN L CA 1 ATOM 6568 C C . ASN D 4 174 ? 4.652 -0.054 7.444 1.00 125.40 ? 175 ASN L C 1 ATOM 6569 O O . ASN D 4 174 ? 5.282 -0.062 6.413 1.00 125.40 ? 175 ASN L O 1 ATOM 6570 C CB . ASN D 4 174 ? 6.757 0.268 8.854 1.00 91.40 ? 175 ASN L CB 1 ATOM 6571 C CG . ASN D 4 174 ? 7.042 -1.199 9.147 1.00 91.40 ? 175 ASN L CG 1 ATOM 6572 O OD1 . ASN D 4 174 ? 6.188 -2.070 8.910 1.00 91.40 ? 175 ASN L OD1 1 ATOM 6573 N ND2 . ASN D 4 174 ? 8.204 -1.470 9.763 1.00 91.40 ? 175 ASN L ND2 1 ATOM 6574 N N . ASN D 4 175 ? 3.449 -0.588 7.569 1.00 99.77 ? 176 ASN L N 1 ATOM 6575 C CA . ASN D 4 175 ? 2.660 -1.268 6.553 1.00 99.77 ? 176 ASN L CA 1 ATOM 6576 C C . ASN D 4 175 ? 3.297 -2.508 5.948 1.00 99.77 ? 176 ASN L C 1 ATOM 6577 O O . ASN D 4 175 ? 3.120 -2.806 4.767 1.00 99.77 ? 176 ASN L O 1 ATOM 6578 C CB . ASN D 4 175 ? 2.209 -0.320 5.403 1.00 92.18 ? 176 ASN L CB 1 ATOM 6579 C CG . ASN D 4 175 ? 0.983 -0.871 4.581 1.00 92.18 ? 176 ASN L CG 1 ATOM 6580 O OD1 . ASN D 4 175 ? -0.101 -1.109 5.103 1.00 92.18 ? 176 ASN L OD1 1 ATOM 6581 N ND2 . ASN D 4 175 ? 1.211 -1.116 3.315 1.00 92.18 ? 176 ASN L ND2 1 ATOM 6582 N N . LYS D 4 176 ? 3.940 -3.281 6.806 1.00 71.74 ? 177 LYS L N 1 ATOM 6583 C CA . LYS D 4 176 ? 4.486 -4.580 6.432 1.00 71.74 ? 177 LYS L CA 1 ATOM 6584 C C . LYS D 4 176 ? 3.912 -5.534 7.464 1.00 71.74 ? 177 LYS L C 1 ATOM 6585 O O . LYS D 4 176 ? 3.507 -5.126 8.552 1.00 71.74 ? 177 LYS L O 1 ATOM 6586 C CB . LYS D 4 176 ? 6.014 -4.740 6.393 1.00 56.12 ? 177 LYS L CB 1 ATOM 6587 C CG . LYS D 4 176 ? 6.742 -4.016 5.292 1.00 56.12 ? 177 LYS L CG 1 ATOM 6588 C CD . LYS D 4 176 ? 8.242 -4.288 5.406 1.00 56.12 ? 177 LYS L CD 1 ATOM 6589 C CE . LYS D 4 176 ? 9.127 -3.621 4.357 1.00 56.12 ? 177 LYS L CE 1 ATOM 6590 N NZ . LYS D 4 176 ? 10.532 -3.947 4.702 1.00 56.12 ? 177 LYS L NZ 1 ATOM 6591 N N . TYR D 4 177 ? 3.882 -6.813 7.151 1.00 62.21 ? 178 TYR L N 1 ATOM 6592 C CA . TYR D 4 177 ? 3.237 -7.721 8.035 1.00 62.21 ? 178 TYR L CA 1 ATOM 6593 C C . TYR D 4 177 ? 4.229 -8.460 8.908 1.00 62.21 ? 178 TYR L C 1 ATOM 6594 O O . TYR D 4 177 ? 5.296 -8.850 8.451 1.00 62.21 ? 178 TYR L O 1 ATOM 6595 C CB . TYR D 4 177 ? 2.448 -8.729 7.219 1.00 86.51 ? 178 TYR L CB 1 ATOM 6596 C CG . TYR D 4 177 ? 1.218 -8.185 6.467 1.00 86.51 ? 178 TYR L CG 1 ATOM 6597 C CD1 . TYR D 4 177 ? -0.057 -8.150 7.039 1.00 86.51 ? 178 TYR L CD1 1 ATOM 6598 C CD2 . TYR D 4 177 ? 1.301 -7.850 5.136 1.00 86.51 ? 178 TYR L CD2 1 ATOM 6599 C CE1 . TYR D 4 177 ? -1.185 -7.805 6.299 1.00 86.51 ? 178 TYR L CE1 1 ATOM 6600 C CE2 . TYR D 4 177 ? 0.177 -7.519 4.405 1.00 86.51 ? 178 TYR L CE2 1 ATOM 6601 C CZ . TYR D 4 177 ? -1.042 -7.503 4.988 1.00 86.51 ? 178 TYR L CZ 1 ATOM 6602 O OH . TYR D 4 177 ? -2.107 -7.213 4.200 1.00 86.51 ? 178 TYR L OH 1 ATOM 6603 N N . ALA D 4 178 ? 3.860 -8.576 10.200 1.00 88.02 ? 179 ALA L N 1 ATOM 6604 C CA . ALA D 4 178 ? 4.574 -9.276 11.300 1.00 88.02 ? 179 ALA L CA 1 ATOM 6605 C C . ALA D 4 178 ? 3.539 -10.164 11.960 1.00 88.02 ? 179 ALA L C 1 ATOM 6606 O O . ALA D 4 178 ? 2.347 -9.896 11.864 1.00 88.02 ? 179 ALA L O 1 ATOM 6607 C CB . ALA D 4 178 ? 5.071 -8.307 12.320 1.00 36.66 ? 179 ALA L CB 1 ATOM 6608 N N . ALA D 4 179 ? 3.973 -11.227 12.613 1.00 81.34 ? 180 ALA L N 1 ATOM 6609 C CA . ALA D 4 179 ? 3.030 -12.143 13.261 1.00 81.34 ? 180 ALA L CA 1 ATOM 6610 C C . ALA D 4 179 ? 3.729 -12.920 14.350 1.00 81.34 ? 180 ALA L C 1 ATOM 6611 O O . ALA D 4 179 ? 4.919 -13.000 14.291 1.00 81.34 ? 180 ALA L O 1 ATOM 6612 C CB . ALA D 4 179 ? 2.450 -13.095 12.258 1.00 73.95 ? 180 ALA L CB 1 ATOM 6613 N N . SER D 4 180 ? 3.020 -13.503 15.323 1.00 68.44 ? 181 SER L N 1 ATOM 6614 C CA . SER D 4 180 ? 3.669 -14.254 16.411 1.00 68.44 ? 181 SER L CA 1 ATOM 6615 C C . SER D 4 180 ? 3.248 -15.715 16.553 1.00 68.44 ? 181 SER L C 1 ATOM 6616 O O . SER D 4 180 ? 2.076 -16.039 16.385 1.00 68.44 ? 181 SER L O 1 ATOM 6617 C CB . SER D 4 180 ? 3.380 -13.582 17.751 1.00 83.46 ? 181 SER L CB 1 ATOM 6618 O OG . SER D 4 180 ? 2.005 -13.507 18.064 1.00 83.46 ? 181 SER L OG 1 ATOM 6619 N N . SER D 4 181 ? 4.213 -16.585 16.865 1.00 69.36 ? 182 SER L N 1 ATOM 6620 C CA . SER D 4 181 ? 3.954 -18.018 17.069 1.00 69.36 ? 182 SER L CA 1 ATOM 6621 C C . SER D 4 181 ? 4.377 -18.407 18.460 1.00 69.36 ? 182 SER L C 1 ATOM 6622 O O . SER D 4 181 ? 5.451 -17.967 18.859 1.00 69.36 ? 182 SER L O 1 ATOM 6623 C CB . SER D 4 181 ? 4.723 -18.898 16.130 1.00 92.39 ? 182 SER L CB 1 ATOM 6624 O OG . SER D 4 181 ? 4.445 -20.246 16.480 1.00 92.39 ? 182 SER L OG 1 ATOM 6625 N N . TYR D 4 182 ? 3.568 -19.207 19.196 1.00 76.91 ? 183 TYR L N 1 ATOM 6626 C CA . TYR D 4 182 ? 3.923 -19.559 20.584 1.00 76.91 ? 183 TYR L CA 1 ATOM 6627 C C . TYR D 4 182 ? 4.068 -21.090 20.728 1.00 76.91 ? 183 TYR L C 1 ATOM 6628 O O . TYR D 4 182 ? 3.334 -21.874 20.158 1.00 76.91 ? 183 TYR L O 1 ATOM 6629 C CB . TYR D 4 182 ? 2.786 -19.153 21.519 1.00 66.24 ? 183 TYR L CB 1 ATOM 6630 C CG . TYR D 4 182 ? 2.592 -17.667 21.609 1.00 66.24 ? 183 TYR L CG 1 ATOM 6631 C CD1 . TYR D 4 182 ? 3.262 -16.899 22.541 1.00 66.24 ? 183 TYR L CD1 1 ATOM 6632 C CD2 . TYR D 4 182 ? 1.707 -17.026 20.755 1.00 66.24 ? 183 TYR L CD2 1 ATOM 6633 C CE1 . TYR D 4 182 ? 3.087 -15.523 22.609 1.00 66.24 ? 183 TYR L CE1 1 ATOM 6634 C CE2 . TYR D 4 182 ? 1.517 -15.660 20.822 1.00 66.24 ? 183 TYR L CE2 1 ATOM 6635 C CZ . TYR D 4 182 ? 2.222 -14.920 21.752 1.00 66.24 ? 183 TYR L CZ 1 ATOM 6636 O OH . TYR D 4 182 ? 2.066 -13.576 21.798 1.00 66.24 ? 183 TYR L OH 1 ATOM 6637 N N . LEU D 4 183 ? 5.051 -21.526 21.478 1.00 103.80 ? 184 LEU L N 1 ATOM 6638 C CA . LEU D 4 183 ? 5.226 -22.952 21.754 1.00 103.80 ? 184 LEU L CA 1 ATOM 6639 C C . LEU D 4 183 ? 5.291 -23.080 23.253 1.00 103.80 ? 184 LEU L C 1 ATOM 6640 O O . LEU D 4 183 ? 6.120 -22.388 23.871 1.00 103.80 ? 184 LEU L O 1 ATOM 6641 C CB . LEU D 4 183 ? 6.571 -23.461 21.205 1.00 107.81 ? 184 LEU L CB 1 ATOM 6642 C CG . LEU D 4 183 ? 7.001 -24.928 21.370 1.00 107.81 ? 184 LEU L CG 1 ATOM 6643 C CD1 . LEU D 4 183 ? 6.051 -25.883 20.729 1.00 107.81 ? 184 LEU L CD1 1 ATOM 6644 C CD2 . LEU D 4 183 ? 8.390 -25.080 20.824 1.00 107.81 ? 184 LEU L CD2 1 ATOM 6645 N N . SER D 4 184 ? 4.501 -23.962 23.865 1.00 109.91 ? 185 SER L N 1 ATOM 6646 C CA . SER D 4 184 ? 4.670 -24.137 25.302 1.00 109.91 ? 185 SER L CA 1 ATOM 6647 C C . SER D 4 184 ? 4.815 -25.575 25.822 1.00 109.91 ? 185 SER L C 1 ATOM 6648 O O . SER D 4 184 ? 4.114 -26.475 25.378 1.00 109.91 ? 185 SER L O 1 ATOM 6649 C CB . SER D 4 184 ? 3.586 -23.348 26.053 1.00 137.97 ? 185 SER L CB 1 ATOM 6650 O OG . SER D 4 184 ? 2.282 -23.765 25.721 1.00 137.97 ? 185 SER L OG 1 ATOM 6651 N N . LEU D 4 185 ? 5.704 -25.778 26.794 1.00 92.62 ? 186 LEU L N 1 ATOM 6652 C CA . LEU D 4 185 ? 5.900 -27.098 27.403 1.00 92.62 ? 186 LEU L CA 1 ATOM 6653 C C . LEU D 4 185 ? 6.370 -26.861 28.846 1.00 92.62 ? 186 LEU L C 1 ATOM 6654 O O . LEU D 4 185 ? 6.888 -25.786 29.158 1.00 92.62 ? 186 LEU L O 1 ATOM 6655 C CB . LEU D 4 185 ? 6.969 -27.885 26.658 1.00 112.45 ? 186 LEU L CB 1 ATOM 6656 C CG . LEU D 4 185 ? 8.262 -27.097 26.440 1.00 112.45 ? 186 LEU L CG 1 ATOM 6657 C CD1 . LEU D 4 185 ? 9.365 -28.016 25.899 1.00 112.45 ? 186 LEU L CD1 1 ATOM 6658 C CD2 . LEU D 4 185 ? 8.021 -25.927 25.521 1.00 112.45 ? 186 LEU L CD2 1 ATOM 6659 N N . THR D 4 186 ? 6.232 -27.854 29.723 1.00 136.75 ? 187 THR L N 1 ATOM 6660 C CA . THR D 4 186 ? 6.690 -27.650 31.103 1.00 136.75 ? 187 THR L CA 1 ATOM 6661 C C . THR D 4 186 ? 8.199 -27.602 31.050 1.00 136.75 ? 187 THR L C 1 ATOM 6662 O O . THR D 4 186 ? 8.813 -28.185 30.161 1.00 136.75 ? 187 THR L O 1 ATOM 6663 C CB . THR D 4 186 ? 6.317 -28.797 32.079 1.00 134.54 ? 187 THR L CB 1 ATOM 6664 O OG1 . THR D 4 186 ? 6.954 -30.009 31.652 1.00 134.54 ? 187 THR L OG1 1 ATOM 6665 C CG2 . THR D 4 186 ? 4.775 -28.971 32.167 1.00 134.54 ? 187 THR L CG2 1 ATOM 6666 N N . PRO D 4 187 ? 8.824 -26.914 32.009 1.00 121.67 ? 188 PRO L N 1 ATOM 6667 C CA . PRO D 4 187 ? 10.279 -26.835 31.997 1.00 121.67 ? 188 PRO L CA 1 ATOM 6668 C C . PRO D 4 187 ? 10.908 -28.212 32.074 1.00 121.67 ? 188 PRO L C 1 ATOM 6669 O O . PRO D 4 187 ? 12.134 -28.338 31.985 1.00 121.67 ? 188 PRO L O 1 ATOM 6670 C CB . PRO D 4 187 ? 10.590 -25.929 33.189 1.00 124.02 ? 188 PRO L CB 1 ATOM 6671 C CG . PRO D 4 187 ? 9.340 -25.973 34.023 1.00 124.02 ? 188 PRO L CG 1 ATOM 6672 C CD . PRO D 4 187 ? 8.250 -26.031 33.031 1.00 124.02 ? 188 PRO L CD 1 ATOM 6673 N N . GLU D 4 188 ? 10.076 -29.238 32.292 1.00 181.18 ? 189 GLU L N 1 ATOM 6674 C CA . GLU D 4 188 ? 10.582 -30.617 32.358 1.00 181.18 ? 189 GLU L CA 1 ATOM 6675 C C . GLU D 4 188 ? 11.262 -30.929 30.972 1.00 181.18 ? 189 GLU L C 1 ATOM 6676 O O . GLU D 4 188 ? 12.427 -31.374 30.877 1.00 181.18 ? 189 GLU L O 1 ATOM 6677 C CB . GLU D 4 188 ? 9.294 -31.471 32.493 1.00 147.20 ? 189 GLU L CB 1 ATOM 6678 C CG . GLU D 4 188 ? 9.331 -32.998 32.595 1.00 147.20 ? 189 GLU L CG 1 ATOM 6679 C CD . GLU D 4 188 ? 9.892 -33.511 33.889 1.00 147.20 ? 189 GLU L CD 1 ATOM 6680 O OE1 . GLU D 4 188 ? 10.060 -32.699 34.820 1.00 147.20 ? 189 GLU L OE1 1 ATOM 6681 O OE2 . GLU D 4 188 ? 10.150 -34.731 33.978 1.00 147.20 ? 189 GLU L OE2 1 ATOM 6682 N N . GLN D 4 189 ? 10.506 -30.630 29.906 1.00 170.34 ? 190 GLN L N 1 ATOM 6683 C CA . GLN D 4 189 ? 10.938 -30.722 28.510 1.00 170.34 ? 190 GLN L CA 1 ATOM 6684 C C . GLN D 4 189 ? 11.956 -29.723 28.044 1.00 170.34 ? 190 GLN L C 1 ATOM 6685 O O . GLN D 4 189 ? 12.828 -30.030 27.242 1.00 170.34 ? 190 GLN L O 1 ATOM 6686 C CB . GLN D 4 189 ? 9.740 -30.688 27.537 1.00 133.22 ? 190 GLN L CB 1 ATOM 6687 C CG . GLN D 4 189 ? 8.848 -31.936 27.550 1.00 133.22 ? 190 GLN L CG 1 ATOM 6688 C CD . GLN D 4 189 ? 7.940 -31.981 28.756 1.00 133.22 ? 190 GLN L CD 1 ATOM 6689 O OE1 . GLN D 4 189 ? 7.353 -30.966 29.148 1.00 133.22 ? 190 GLN L OE1 1 ATOM 6690 N NE2 . GLN D 4 189 ? 7.833 -33.157 29.366 1.00 133.22 ? 190 GLN L NE2 1 ATOM 6691 N N . TRP D 4 190 ? 11.758 -28.492 28.519 1.00 112.20 ? 191 TRP L N 1 ATOM 6692 C CA . TRP D 4 190 ? 12.565 -27.371 28.090 1.00 112.20 ? 191 TRP L CA 1 ATOM 6693 C C . TRP D 4 190 ? 13.984 -27.703 28.452 1.00 112.20 ? 191 TRP L C 1 ATOM 6694 O O . TRP D 4 190 ? 14.898 -27.503 27.642 1.00 112.20 ? 191 TRP L O 1 ATOM 6695 C CB . TRP D 4 190 ? 12.139 -26.073 28.775 1.00 94.37 ? 191 TRP L CB 1 ATOM 6696 C CG . TRP D 4 190 ? 12.927 -24.902 28.374 1.00 94.37 ? 191 TRP L CG 1 ATOM 6697 C CD1 . TRP D 4 190 ? 12.629 -24.121 27.328 1.00 94.37 ? 191 TRP L CD1 1 ATOM 6698 C CD2 . TRP D 4 190 ? 14.086 -24.340 28.972 1.00 94.37 ? 191 TRP L CD2 1 ATOM 6699 N NE1 . TRP D 4 190 ? 13.510 -23.097 27.212 1.00 94.37 ? 191 TRP L NE1 1 ATOM 6700 C CE2 . TRP D 4 190 ? 14.427 -23.198 28.213 1.00 94.37 ? 191 TRP L CE2 1 ATOM 6701 C CE3 . TRP D 4 190 ? 14.887 -24.682 30.076 1.00 94.37 ? 191 TRP L CE3 1 ATOM 6702 C CZ2 . TRP D 4 190 ? 15.540 -22.373 28.510 1.00 94.37 ? 191 TRP L CZ2 1 ATOM 6703 C CZ3 . TRP D 4 190 ? 16.035 -23.847 30.391 1.00 94.37 ? 191 TRP L CZ3 1 ATOM 6704 C CH2 . TRP D 4 190 ? 16.333 -22.706 29.595 1.00 94.37 ? 191 TRP L CH2 1 ATOM 6705 N N . LYS D 4 191 ? 14.176 -28.158 29.698 1.00 113.00 ? 192 LYS L N 1 ATOM 6706 C CA . LYS D 4 191 ? 15.519 -28.498 30.159 1.00 113.00 ? 192 LYS L CA 1 ATOM 6707 C C . LYS D 4 191 ? 16.340 -29.613 29.437 1.00 113.00 ? 192 LYS L C 1 ATOM 6708 O O . LYS D 4 191 ? 17.575 -29.509 29.238 1.00 113.00 ? 192 LYS L O 1 ATOM 6709 C CB . LYS D 4 191 ? 15.546 -28.755 31.680 1.00 85.96 ? 192 LYS L CB 1 ATOM 6710 C CG . LYS D 4 191 ? 15.338 -27.515 32.580 1.00 85.96 ? 192 LYS L CG 1 ATOM 6711 C CD . LYS D 4 191 ? 15.379 -27.864 34.122 1.00 85.96 ? 192 LYS L CD 1 ATOM 6712 C CE . LYS D 4 191 ? 14.253 -28.739 34.680 1.00 85.96 ? 192 LYS L CE 1 ATOM 6713 N NZ . LYS D 4 191 ? 14.513 -29.026 36.075 1.00 85.96 ? 192 LYS L NZ 1 ATOM 6714 N N . SER D 4 192 ? 15.654 -30.688 29.064 1.00 121.56 ? 193 SER L N 1 ATOM 6715 C CA . SER D 4 192 ? 16.326 -31.814 28.433 1.00 121.56 ? 193 SER L CA 1 ATOM 6716 C C . SER D 4 192 ? 16.971 -31.864 27.026 1.00 121.56 ? 193 SER L C 1 ATOM 6717 O O . SER D 4 192 ? 18.079 -32.413 26.912 1.00 121.56 ? 193 SER L O 1 ATOM 6718 C CB . SER D 4 192 ? 15.396 -33.013 28.649 1.00 113.47 ? 193 SER L CB 1 ATOM 6719 O OG . SER D 4 192 ? 14.065 -32.717 28.216 1.00 113.47 ? 193 SER L OG 1 ATOM 6720 N N . HIS D 4 193 ? 16.352 -31.256 25.994 1.00 138.16 ? 194 HIS L N 1 ATOM 6721 C CA . HIS D 4 193 ? 16.903 -31.256 24.609 1.00 138.16 ? 194 HIS L CA 1 ATOM 6722 C C . HIS D 4 193 ? 18.009 -30.252 24.339 1.00 138.16 ? 194 HIS L C 1 ATOM 6723 O O . HIS D 4 193 ? 18.102 -29.251 25.019 1.00 138.16 ? 194 HIS L O 1 ATOM 6724 C CB . HIS D 4 193 ? 15.805 -31.117 23.555 1.00 147.33 ? 194 HIS L CB 1 ATOM 6725 C CG . HIS D 4 193 ? 14.918 -32.333 23.423 1.00 147.33 ? 194 HIS L CG 1 ATOM 6726 N ND1 . HIS D 4 193 ? 15.346 -33.513 22.838 1.00 147.33 ? 194 HIS L ND1 1 ATOM 6727 C CD2 . HIS D 4 193 ? 13.602 -32.517 23.712 1.00 147.33 ? 194 HIS L CD2 1 ATOM 6728 C CE1 . HIS D 4 193 ? 14.332 -34.362 22.766 1.00 147.33 ? 194 HIS L CE1 1 ATOM 6729 N NE2 . HIS D 4 193 ? 13.263 -33.781 23.287 1.00 147.33 ? 194 HIS L NE2 1 ATOM 6730 N N . ARG D 4 194 ? 18.866 -30.527 23.360 1.00 176.19 ? 195 ARG L N 1 ATOM 6731 C CA . ARG D 4 194 ? 20.011 -29.642 23.100 1.00 176.19 ? 195 ARG L CA 1 ATOM 6732 C C . ARG D 4 194 ? 19.513 -28.223 22.746 1.00 176.19 ? 195 ARG L C 1 ATOM 6733 O O . ARG D 4 194 ? 20.092 -27.219 23.165 1.00 176.19 ? 195 ARG L O 1 ATOM 6734 C CB . ARG D 4 194 ? 20.705 -30.114 21.810 1.00 132.55 ? 195 ARG L CB 1 ATOM 6735 C CG . ARG D 4 194 ? 21.448 -31.445 21.815 1.00 132.55 ? 195 ARG L CG 1 ATOM 6736 C CD . ARG D 4 194 ? 22.782 -31.554 22.469 1.00 132.55 ? 195 ARG L CD 1 ATOM 6737 N NE . ARG D 4 194 ? 23.187 -32.946 22.282 1.00 132.55 ? 195 ARG L NE 1 ATOM 6738 C CZ . ARG D 4 194 ? 23.621 -33.450 21.117 1.00 132.55 ? 195 ARG L CZ 1 ATOM 6739 N NH1 . ARG D 4 194 ? 23.713 -32.677 20.026 1.00 132.55 ? 195 ARG L NH1 1 ATOM 6740 N NH2 . ARG D 4 194 ? 23.941 -34.739 21.025 1.00 132.55 ? 195 ARG L NH2 1 ATOM 6741 N N . SER D 4 195 ? 18.444 -28.178 21.944 1.00 127.73 ? 196 SER L N 1 ATOM 6742 C CA . SER D 4 195 ? 17.843 -26.927 21.451 1.00 127.73 ? 196 SER L CA 1 ATOM 6743 C C . SER D 4 195 ? 16.403 -26.978 20.868 1.00 127.73 ? 196 SER L C 1 ATOM 6744 O O . SER D 4 195 ? 15.909 -28.049 20.522 1.00 127.73 ? 196 SER L O 1 ATOM 6745 C CB . SER D 4 195 ? 18.820 -26.249 20.457 1.00 144.49 ? 196 SER L CB 1 ATOM 6746 O OG . SER D 4 195 ? 18.934 -26.959 19.240 1.00 144.49 ? 196 SER L OG 1 ATOM 6747 N N . TYR D 4 196 ? 15.721 -25.837 20.799 1.00 137.80 ? 197 TYR L N 1 ATOM 6748 C CA . TYR D 4 196 ? 14.413 -25.763 20.146 1.00 137.80 ? 197 TYR L CA 1 ATOM 6749 C C . TYR D 4 196 ? 14.437 -24.777 18.983 1.00 137.80 ? 197 TYR L C 1 ATOM 6750 O O . TYR D 4 196 ? 15.097 -23.734 19.078 1.00 137.80 ? 197 TYR L O 1 ATOM 6751 C CB . TYR D 4 196 ? 13.344 -25.363 21.130 1.00 146.55 ? 197 TYR L CB 1 ATOM 6752 C CG . TYR D 4 196 ? 13.112 -26.465 22.072 1.00 146.55 ? 197 TYR L CG 1 ATOM 6753 C CD1 . TYR D 4 196 ? 12.175 -27.430 21.803 1.00 146.55 ? 197 TYR L CD1 1 ATOM 6754 C CD2 . TYR D 4 196 ? 13.923 -26.626 23.171 1.00 146.55 ? 197 TYR L CD2 1 ATOM 6755 C CE1 . TYR D 4 196 ? 12.053 -28.542 22.605 1.00 146.55 ? 197 TYR L CE1 1 ATOM 6756 C CE2 . TYR D 4 196 ? 13.819 -27.735 23.978 1.00 146.55 ? 197 TYR L CE2 1 ATOM 6757 C CZ . TYR D 4 196 ? 12.881 -28.697 23.691 1.00 146.55 ? 197 TYR L CZ 1 ATOM 6758 O OH . TYR D 4 196 ? 12.786 -29.829 24.477 1.00 146.55 ? 197 TYR L OH 1 ATOM 6759 N N . SER D 4 197 ? 13.779 -25.108 17.868 1.00 91.62 ? 198 SER L N 1 ATOM 6760 C CA . SER D 4 197 ? 13.737 -24.163 16.742 1.00 91.62 ? 198 SER L CA 1 ATOM 6761 C C . SER D 4 197 ? 12.386 -23.810 16.081 1.00 91.62 ? 198 SER L C 1 ATOM 6762 O O . SER D 4 197 ? 11.505 -24.653 15.875 1.00 91.62 ? 198 SER L O 1 ATOM 6763 C CB . SER D 4 197 ? 14.777 -24.548 15.679 1.00 86.94 ? 198 SER L CB 1 ATOM 6764 O OG . SER D 4 197 ? 16.080 -24.434 16.216 1.00 86.94 ? 198 SER L OG 1 ATOM 6765 N N . CYS D 4 198 ? 12.256 -22.530 15.755 1.00 127.66 ? 199 CYS L N 1 ATOM 6766 C CA . CYS D 4 198 ? 11.088 -21.972 15.093 1.00 127.66 ? 199 CYS L CA 1 ATOM 6767 C C . CYS D 4 198 ? 11.527 -21.720 13.643 1.00 127.66 ? 199 CYS L C 1 ATOM 6768 O O . CYS D 4 198 ? 12.573 -21.098 13.441 1.00 127.66 ? 199 CYS L O 1 ATOM 6769 C CB . CYS D 4 198 ? 10.734 -20.636 15.795 1.00 119.13 ? 199 CYS L CB 1 ATOM 6770 S SG . CYS D 4 198 ? 9.636 -19.458 14.960 1.00 119.13 ? 199 CYS L SG 1 ATOM 6771 N N . GLN D 4 199 ? 10.773 -22.166 12.627 1.00 121.48 ? 200 GLN L N 1 ATOM 6772 C CA . GLN D 4 199 ? 11.195 -21.811 11.268 1.00 121.48 ? 200 GLN L CA 1 ATOM 6773 C C . GLN D 4 199 ? 10.031 -21.254 10.439 1.00 121.48 ? 200 GLN L C 1 ATOM 6774 O O . GLN D 4 199 ? 8.893 -21.723 10.520 1.00 121.48 ? 200 GLN L O 1 ATOM 6775 C CB . GLN D 4 199 ? 11.834 -23.019 10.584 1.00 109.87 ? 200 GLN L CB 1 ATOM 6776 C CG . GLN D 4 199 ? 10.951 -24.223 10.361 1.00 109.87 ? 200 GLN L CG 1 ATOM 6777 C CD . GLN D 4 199 ? 11.735 -25.372 9.697 1.00 109.87 ? 200 GLN L CD 1 ATOM 6778 O OE1 . GLN D 4 199 ? 12.876 -25.668 10.055 1.00 109.87 ? 200 GLN L OE1 1 ATOM 6779 N NE2 . GLN D 4 199 ? 11.112 -26.020 8.731 1.00 109.87 ? 200 GLN L NE2 1 ATOM 6780 N N . VAL D 4 200 ? 10.398 -20.352 9.530 1.00 103.56 ? 201 VAL L N 1 ATOM 6781 C CA . VAL D 4 200 ? 9.446 -19.611 8.731 1.00 103.56 ? 201 VAL L CA 1 ATOM 6782 C C . VAL D 4 200 ? 9.607 -19.833 7.271 1.00 103.56 ? 201 VAL L C 1 ATOM 6783 O O . VAL D 4 200 ? 10.666 -19.615 6.705 1.00 103.56 ? 201 VAL L O 1 ATOM 6784 C CB . VAL D 4 200 ? 9.632 -18.100 8.950 1.00 90.10 ? 201 VAL L CB 1 ATOM 6785 C CG1 . VAL D 4 200 ? 8.657 -17.346 8.132 1.00 90.10 ? 201 VAL L CG1 1 ATOM 6786 C CG2 . VAL D 4 200 ? 9.443 -17.746 10.395 1.00 90.10 ? 201 VAL L CG2 1 ATOM 6787 N N . THR D 4 201 ? 8.497 -20.144 6.646 1.00 76.57 ? 202 THR L N 1 ATOM 6788 C CA . THR D 4 201 ? 8.519 -20.388 5.243 1.00 76.57 ? 202 THR L CA 1 ATOM 6789 C C . THR D 4 201 ? 7.879 -19.141 4.666 1.00 76.57 ? 202 THR L C 1 ATOM 6790 O O . THR D 4 201 ? 6.803 -18.772 5.053 1.00 76.57 ? 202 THR L O 1 ATOM 6791 C CB . THR D 4 201 ? 7.656 -21.613 4.880 1.00 111.21 ? 202 THR L CB 1 ATOM 6792 O OG1 . THR D 4 201 ? 8.149 -22.777 5.554 1.00 111.21 ? 202 THR L OG1 1 ATOM 6793 C CG2 . THR D 4 201 ? 7.680 -21.850 3.359 1.00 111.21 ? 202 THR L CG2 1 ATOM 6794 N N . HIS D 4 202 ? 8.561 -18.395 3.833 1.00 115.26 ? 203 HIS L N 1 ATOM 6795 C CA . HIS D 4 202 ? 7.848 -17.285 3.283 1.00 115.26 ? 203 HIS L CA 1 ATOM 6796 C C . HIS D 4 202 ? 8.037 -17.367 1.802 1.00 115.26 ? 203 HIS L C 1 ATOM 6797 O O . HIS D 4 202 ? 9.148 -17.252 1.303 1.00 115.26 ? 203 HIS L O 1 ATOM 6798 C CB . HIS D 4 202 ? 8.437 -16.020 3.866 1.00 84.60 ? 203 HIS L CB 1 ATOM 6799 C CG . HIS D 4 202 ? 7.791 -14.779 3.381 1.00 84.60 ? 203 HIS L CG 1 ATOM 6800 N ND1 . HIS D 4 202 ? 6.426 -14.616 3.401 1.00 84.60 ? 203 HIS L ND1 1 ATOM 6801 C CD2 . HIS D 4 202 ? 8.310 -13.590 2.994 1.00 84.60 ? 203 HIS L CD2 1 ATOM 6802 C CE1 . HIS D 4 202 ? 6.124 -13.379 3.047 1.00 84.60 ? 203 HIS L CE1 1 ATOM 6803 N NE2 . HIS D 4 202 ? 7.249 -12.734 2.798 1.00 84.60 ? 203 HIS L NE2 1 ATOM 6804 N N . GLU D 4 203 ? 6.964 -17.549 1.072 1.00 65.62 ? 204 GLU L N 1 ATOM 6805 C CA . GLU D 4 203 ? 7.085 -17.565 -0.392 1.00 65.62 ? 204 GLU L CA 1 ATOM 6806 C C . GLU D 4 203 ? 8.019 -18.636 -1.047 1.00 65.62 ? 204 GLU L C 1 ATOM 6807 O O . GLU D 4 203 ? 8.720 -18.343 -2.043 1.00 65.62 ? 204 GLU L O 1 ATOM 6808 C CB . GLU D 4 203 ? 7.548 -16.167 -0.855 1.00 130.82 ? 204 GLU L CB 1 ATOM 6809 C CG . GLU D 4 203 ? 6.495 -15.072 -0.674 1.00 130.82 ? 204 GLU L CG 1 ATOM 6810 C CD . GLU D 4 203 ? 5.330 -15.216 -1.607 1.00 130.82 ? 204 GLU L CD 1 ATOM 6811 O OE1 . GLU D 4 203 ? 5.567 -15.653 -2.754 1.00 130.82 ? 204 GLU L OE1 1 ATOM 6812 O OE2 . GLU D 4 203 ? 4.185 -14.910 -1.189 1.00 130.82 ? 204 GLU L OE2 1 ATOM 6813 N N . GLY D 4 204 ? 8.007 -19.865 -0.528 1.00 106.20 ? 205 GLY L N 1 ATOM 6814 C CA . GLY D 4 204 ? 8.827 -20.910 -1.135 1.00 106.20 ? 205 GLY L CA 1 ATOM 6815 C C . GLY D 4 204 ? 10.233 -20.996 -0.541 1.00 106.20 ? 205 GLY L C 1 ATOM 6816 O O . GLY D 4 204 ? 11.012 -21.913 -0.784 1.00 106.20 ? 205 GLY L O 1 ATOM 6817 N N . SER D 4 205 ? 10.559 -20.009 0.259 1.00 93.06 ? 206 SER L N 1 ATOM 6818 C CA . SER D 4 205 ? 11.859 -19.919 0.858 1.00 93.06 ? 206 SER L CA 1 ATOM 6819 C C . SER D 4 205 ? 11.870 -19.739 2.408 1.00 93.06 ? 206 SER L C 1 ATOM 6820 O O . SER D 4 205 ? 11.095 -18.967 2.995 1.00 93.06 ? 206 SER L O 1 ATOM 6821 C CB . SER D 4 205 ? 12.600 -18.857 0.039 1.00 90.46 ? 206 SER L CB 1 ATOM 6822 O OG . SER D 4 205 ? 11.840 -17.670 -0.109 1.00 90.46 ? 206 SER L OG 1 ATOM 6823 N N . THR D 4 206 ? 12.834 -20.370 3.064 1.00 108.97 ? 207 THR L N 1 ATOM 6824 C CA . THR D 4 206 ? 12.872 -20.425 4.530 1.00 108.97 ? 207 THR L CA 1 ATOM 6825 C C . THR D 4 206 ? 14.047 -19.855 5.284 1.00 108.97 ? 207 THR L C 1 ATOM 6826 O O . THR D 4 206 ? 15.196 -20.156 4.960 1.00 108.97 ? 207 THR L O 1 ATOM 6827 C CB . THR D 4 206 ? 12.737 -21.875 5.045 1.00 106.45 ? 207 THR L CB 1 ATOM 6828 O OG1 . THR D 4 206 ? 11.498 -22.433 4.610 1.00 106.45 ? 207 THR L OG1 1 ATOM 6829 C CG2 . THR D 4 206 ? 12.836 -21.926 6.562 1.00 106.45 ? 207 THR L CG2 1 ATOM 6830 N N . VAL D 4 207 ? 13.747 -19.019 6.290 1.00 146.72 ? 208 VAL L N 1 ATOM 6831 C CA . VAL D 4 207 ? 14.800 -18.414 7.104 1.00 146.72 ? 208 VAL L CA 1 ATOM 6832 C C . VAL D 4 207 ? 14.508 -18.941 8.511 1.00 146.72 ? 208 VAL L C 1 ATOM 6833 O O . VAL D 4 207 ? 13.380 -18.835 8.999 1.00 146.72 ? 208 VAL L O 1 ATOM 6834 C CB . VAL D 4 207 ? 14.686 -16.858 7.079 1.00 126.03 ? 208 VAL L CB 1 ATOM 6835 C CG1 . VAL D 4 207 ? 15.805 -16.227 7.944 1.00 126.03 ? 208 VAL L CG1 1 ATOM 6836 C CG2 . VAL D 4 207 ? 14.767 -16.344 5.619 1.00 126.03 ? 208 VAL L CG2 1 ATOM 6837 N N . GLU D 4 208 ? 15.554 -19.482 9.156 1.00 92.15 ? 209 GLU L N 1 ATOM 6838 C CA . GLU D 4 208 ? 15.412 -20.115 10.453 1.00 92.15 ? 209 GLU L CA 1 ATOM 6839 C C . GLU D 4 208 ? 16.234 -19.785 11.686 1.00 92.15 ? 209 GLU L C 1 ATOM 6840 O O . GLU D 4 208 ? 17.427 -19.530 11.560 1.00 92.15 ? 209 GLU L O 1 ATOM 6841 C CB . GLU D 4 208 ? 15.416 -21.629 10.229 1.00 126.52 ? 209 GLU L CB 1 ATOM 6842 C CG . GLU D 4 208 ? 15.274 -22.463 11.488 1.00 126.52 ? 209 GLU L CG 1 ATOM 6843 C CD . GLU D 4 208 ? 15.285 -23.953 11.204 1.00 126.52 ? 209 GLU L CD 1 ATOM 6844 O OE1 . GLU D 4 208 ? 15.212 -24.312 10.024 1.00 126.52 ? 209 GLU L OE1 1 ATOM 6845 O OE2 . GLU D 4 208 ? 15.405 -24.769 12.141 1.00 126.52 ? 209 GLU L OE2 1 ATOM 6846 N N . LYS D 4 209 ? 15.571 -19.732 12.857 1.00 82.50 ? 210 LYS L N 1 ATOM 6847 C CA . LYS D 4 209 ? 16.232 -19.594 14.156 1.00 82.50 ? 210 LYS L CA 1 ATOM 6848 C C . LYS D 4 209 ? 16.055 -20.677 15.214 1.00 82.50 ? 210 LYS L C 1 ATOM 6849 O O . LYS D 4 209 ? 14.978 -21.214 15.456 1.00 82.50 ? 210 LYS L O 1 ATOM 6850 C CB . LYS D 4 209 ? 16.127 -18.233 14.843 1.00 132.34 ? 210 LYS L CB 1 ATOM 6851 C CG . LYS D 4 209 ? 16.916 -17.138 14.165 1.00 132.34 ? 210 LYS L CG 1 ATOM 6852 C CD . LYS D 4 209 ? 16.788 -15.790 14.878 1.00 132.34 ? 210 LYS L CD 1 ATOM 6853 C CE . LYS D 4 209 ? 17.614 -14.714 14.141 1.00 132.34 ? 210 LYS L CE 1 ATOM 6854 N NZ . LYS D 4 209 ? 17.577 -13.360 14.765 1.00 132.34 ? 210 LYS L NZ 1 ATOM 6855 N N . THR D 4 210 ? 17.188 -20.934 15.876 1.00 89.25 ? 211 THR L N 1 ATOM 6856 C CA . THR D 4 210 ? 17.361 -21.983 16.868 1.00 89.25 ? 211 THR L CA 1 ATOM 6857 C C . THR D 4 210 ? 17.759 -21.384 18.195 1.00 89.25 ? 211 THR L C 1 ATOM 6858 O O . THR D 4 210 ? 18.676 -20.558 18.232 1.00 89.25 ? 211 THR L O 1 ATOM 6859 C CB . THR D 4 210 ? 18.560 -22.832 16.492 1.00 122.89 ? 211 THR L CB 1 ATOM 6860 O OG1 . THR D 4 210 ? 18.355 -23.423 15.209 1.00 122.89 ? 211 THR L OG1 1 ATOM 6861 C CG2 . THR D 4 210 ? 18.767 -23.931 17.527 1.00 122.89 ? 211 THR L CG2 1 ATOM 6862 N N . MET D 4 211 ? 17.060 -21.771 19.270 1.00 127.89 ? 212 MET L N 1 ATOM 6863 C CA . MET D 4 211 ? 17.374 -21.311 20.643 1.00 127.89 ? 212 MET L CA 1 ATOM 6864 C C . MET D 4 211 ? 17.693 -22.514 21.534 1.00 127.89 ? 212 MET L C 1 ATOM 6865 O O . MET D 4 211 ? 16.909 -23.466 21.551 1.00 127.89 ? 212 MET L O 1 ATOM 6866 C CB . MET D 4 211 ? 16.203 -20.566 21.276 1.00 122.13 ? 212 MET L CB 1 ATOM 6867 C CG . MET D 4 211 ? 16.554 -20.097 22.648 1.00 122.13 ? 212 MET L CG 1 ATOM 6868 S SD . MET D 4 211 ? 15.196 -19.396 23.567 1.00 122.13 ? 212 MET L SD 1 ATOM 6869 C CE . MET D 4 211 ? 14.191 -20.799 23.898 1.00 122.13 ? 212 MET L CE 1 ATOM 6870 N N . ALA D 4 212 ? 18.794 -22.485 22.285 1.00 150.14 ? 213 ALA L N 1 ATOM 6871 C CA . ALA D 4 212 ? 19.110 -23.633 23.150 1.00 150.14 ? 213 ALA L CA 1 ATOM 6872 C C . ALA D 4 212 ? 19.168 -23.328 24.668 1.00 150.14 ? 213 ALA L C 1 ATOM 6873 O O . ALA D 4 212 ? 19.851 -22.396 25.104 1.00 150.14 ? 213 ALA L O 1 ATOM 6874 C CB . ALA D 4 212 ? 20.430 -24.225 22.705 1.00 86.05 ? 213 ALA L CB 1 ATOM 6875 N N . HIS D 4 213 ? 18.463 -24.140 25.466 1.00 91.70 ? 214 HIS L N 1 ATOM 6876 C CA . HIS D 4 213 ? 18.417 -23.979 26.934 1.00 91.70 ? 214 HIS L CA 1 ATOM 6877 C C . HIS D 4 213 ? 19.801 -24.108 27.571 1.00 91.70 ? 214 HIS L C 1 ATOM 6878 O O . HIS D 4 213 ? 20.168 -23.370 28.493 1.00 91.70 ? 214 HIS L O 1 ATOM 6879 C CB . HIS D 4 213 ? 17.474 -25.026 27.556 1.00 126.93 ? 214 HIS L CB 1 ATOM 6880 C CG . HIS D 4 213 ? 18.169 -26.095 28.353 1.00 126.93 ? 214 HIS L CG 1 ATOM 6881 N ND1 . HIS D 4 213 ? 18.290 -26.034 29.727 1.00 126.93 ? 214 HIS L ND1 1 ATOM 6882 C CD2 . HIS D 4 213 ? 18.756 -27.257 27.975 1.00 126.93 ? 214 HIS L CD2 1 ATOM 6883 C CE1 . HIS D 4 213 ? 18.917 -27.116 30.158 1.00 126.93 ? 214 HIS L CE1 1 ATOM 6884 N NE2 . HIS D 4 213 ? 19.212 -27.873 29.115 1.00 126.93 ? 214 HIS L NE2 1 ATOM 6885 N N . ALA D 4 214 ? 20.561 -25.061 27.044 1.00 131.23 ? 215 ALA L N 1 ATOM 6886 C CA . ALA D 4 214 ? 21.880 -25.356 27.540 1.00 131.23 ? 215 ALA L CA 1 ATOM 6887 C C . ALA D 4 214 ? 22.781 -24.157 27.283 1.00 131.23 ? 215 ALA L C 1 ATOM 6888 O O . ALA D 4 214 ? 22.242 -23.146 26.753 1.00 131.23 ? 215 ALA L O 1 ATOM 6889 C CB . ALA D 4 214 ? 22.417 -26.605 26.853 1.00 133.60 ? 215 ALA L CB 1 HETATM 6890 C C1 . NAG E 5 . ? -66.416 -31.132 8.681 1.00 105.63 ? 1000 NAG G C1 1 HETATM 6891 C C2 . NAG E 5 . ? -65.869 -29.711 8.750 1.00 105.63 ? 1000 NAG G C2 1 HETATM 6892 C C3 . NAG E 5 . ? -65.214 -29.165 10.067 1.00 105.63 ? 1000 NAG G C3 1 HETATM 6893 C C4 . NAG E 5 . ? -66.008 -29.491 11.352 1.00 105.63 ? 1000 NAG G C4 1 HETATM 6894 C C5 . NAG E 5 . ? -66.367 -30.976 11.298 1.00 105.63 ? 1000 NAG G C5 1 HETATM 6895 C C6 . NAG E 5 . ? -67.174 -31.333 12.584 1.00 105.63 ? 1000 NAG G C6 1 HETATM 6896 C C7 . NAG E 5 . ? -64.919 -28.476 6.993 1.00 105.63 ? 1000 NAG G C7 1 HETATM 6897 C C8 . NAG E 5 . ? -63.738 -27.588 7.304 1.00 105.63 ? 1000 NAG G C8 1 HETATM 6898 N N2 . NAG E 5 . ? -64.930 -29.594 7.681 1.00 105.63 ? 1000 NAG G N2 1 HETATM 6899 O O3 . NAG E 5 . ? -65.101 -27.744 9.944 1.00 105.63 ? 1000 NAG G O3 1 HETATM 6900 O O4 . NAG E 5 . ? -65.235 -29.180 12.538 1.00 105.63 ? 1000 NAG G O4 1 HETATM 6901 O O5 . NAG E 5 . ? -67.144 -31.342 10.020 1.00 105.63 ? 1000 NAG G O5 1 HETATM 6902 O O6 . NAG E 5 . ? -66.529 -30.900 13.804 1.00 105.63 ? 1000 NAG G O6 1 HETATM 6903 O O7 . NAG E 5 . ? -65.805 -28.137 6.186 1.00 105.63 ? 1000 NAG G O7 1 HETATM 6904 C C1 . NAG F 5 . ? -59.175 -32.874 -27.111 1.00 122.97 ? 1500 NAG G C1 1 HETATM 6905 C C2 . NAG F 5 . ? -58.645 -33.855 -28.339 1.00 122.97 ? 1500 NAG G C2 1 HETATM 6906 C C3 . NAG F 5 . ? -59.618 -33.779 -29.517 1.00 122.97 ? 1500 NAG G C3 1 HETATM 6907 C C4 . NAG F 5 . ? -60.921 -33.062 -29.156 1.00 122.97 ? 1500 NAG G C4 1 HETATM 6908 C C5 . NAG F 5 . ? -60.637 -31.654 -28.558 1.00 122.97 ? 1500 NAG G C5 1 HETATM 6909 C C6 . NAG F 5 . ? -61.739 -31.225 -27.633 1.00 122.97 ? 1500 NAG G C6 1 HETATM 6910 C C7 . NAG F 5 . ? -56.626 -34.238 -29.821 1.00 122.97 ? 1500 NAG G C7 1 HETATM 6911 C C8 . NAG F 5 . ? -57.046 -34.342 -31.312 1.00 122.97 ? 1500 NAG G C8 1 HETATM 6912 N N2 . NAG F 5 . ? -57.315 -33.484 -28.916 1.00 122.97 ? 1500 NAG G N2 1 HETATM 6913 O O3 . NAG F 5 . ? -59.888 -35.082 -29.988 1.00 122.97 ? 1500 NAG G O3 1 HETATM 6914 O O4 . NAG F 5 . ? -61.735 -32.940 -30.321 1.00 122.97 ? 1500 NAG G O4 1 HETATM 6915 O O5 . NAG F 5 . ? -59.412 -31.622 -27.761 1.00 122.97 ? 1500 NAG G O5 1 HETATM 6916 O O6 . NAG F 5 . ? -62.981 -31.691 -28.106 1.00 122.97 ? 1500 NAG G O6 1 HETATM 6917 O O7 . NAG F 5 . ? -55.599 -34.835 -29.491 1.00 122.97 ? 1500 NAG G O7 1 HETATM 6918 C C1 . NAG G 5 . ? -42.520 -37.310 0.142 1.00 125.36 ? 2000 NAG G C1 1 HETATM 6919 C C2 . NAG G 5 . ? -41.682 -38.695 -0.074 1.00 125.36 ? 2000 NAG G C2 1 HETATM 6920 C C3 . NAG G 5 . ? -40.649 -38.661 -1.253 1.00 125.36 ? 2000 NAG G C3 1 HETATM 6921 C C4 . NAG G 5 . ? -41.238 -38.066 -2.517 1.00 125.36 ? 2000 NAG G C4 1 HETATM 6922 C C5 . NAG G 5 . ? -42.082 -36.763 -2.240 1.00 125.36 ? 2000 NAG G C5 1 HETATM 6923 C C6 . NAG G 5 . ? -42.944 -36.367 -3.464 1.00 125.36 ? 2000 NAG G C6 1 HETATM 6924 C C7 . NAG G 5 . ? -41.490 -39.648 2.135 1.00 125.36 ? 2000 NAG G C7 1 HETATM 6925 C C8 . NAG G 5 . ? -41.303 -38.890 3.437 1.00 125.36 ? 2000 NAG G C8 1 HETATM 6926 N N2 . NAG G 5 . ? -40.906 -39.091 1.083 1.00 125.36 ? 2000 NAG G N2 1 HETATM 6927 O O3 . NAG G 5 . ? -40.158 -39.972 -1.555 1.00 125.36 ? 2000 NAG G O3 1 HETATM 6928 O O4 . NAG G 5 . ? -40.167 -37.783 -3.424 1.00 125.36 ? 2000 NAG G O4 1 HETATM 6929 O O5 . NAG G 5 . ? -43.051 -36.905 -1.132 1.00 125.36 ? 2000 NAG G O5 1 HETATM 6930 O O6 . NAG G 5 . ? -42.385 -36.790 -4.700 1.00 125.36 ? 2000 NAG G O6 1 HETATM 6931 O O7 . NAG G 5 . ? -42.152 -40.703 2.089 1.00 125.36 ? 2000 NAG G O7 1 HETATM 6932 C C1 . NAG H 5 . ? -53.501 -30.993 24.643 1.00 136.07 ? 2500 NAG G C1 1 HETATM 6933 C C2 . NAG H 5 . ? -52.276 -30.890 25.883 1.00 136.07 ? 2500 NAG G C2 1 HETATM 6934 C C3 . NAG H 5 . ? -52.333 -31.843 27.177 1.00 136.07 ? 2500 NAG G C3 1 HETATM 6935 C C4 . NAG H 5 . ? -53.797 -32.177 27.524 1.00 136.07 ? 2500 NAG G C4 1 HETATM 6936 C C5 . NAG H 5 . ? -54.653 -32.284 26.233 1.00 136.07 ? 2500 NAG G C5 1 HETATM 6937 C C6 . NAG H 5 . ? -56.088 -32.545 26.480 1.00 136.07 ? 2500 NAG G C6 1 HETATM 6938 C C7 . NAG H 5 . ? -50.364 -29.431 26.644 1.00 136.07 ? 2500 NAG G C7 1 HETATM 6939 C C8 . NAG H 5 . ? -49.024 -29.877 27.265 1.00 136.07 ? 2500 NAG G C8 1 HETATM 6940 N N2 . NAG H 5 . ? -50.944 -30.242 25.697 1.00 136.07 ? 2500 NAG G N2 1 HETATM 6941 O O3 . NAG H 5 . ? -51.781 -31.153 28.312 1.00 136.07 ? 2500 NAG G O3 1 HETATM 6942 O O4 . NAG H 5 . ? -53.873 -33.391 28.278 1.00 136.07 ? 2500 NAG G O4 1 HETATM 6943 O O5 . NAG H 5 . ? -54.651 -31.063 25.454 1.00 136.07 ? 2500 NAG G O5 1 HETATM 6944 O O6 . NAG H 5 . ? -56.776 -32.645 25.238 1.00 136.07 ? 2500 NAG G O6 1 HETATM 6945 O O7 . NAG H 5 . ? -50.827 -28.318 26.997 1.00 136.07 ? 2500 NAG G O7 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 LYS 1 1 ? ? ? C . n A 1 2 LYS 2 2 2 LYS LYS C . n A 1 3 VAL 3 3 3 VAL VAL C . n A 1 4 VAL 4 4 4 VAL VAL C . n A 1 5 LEU 5 5 5 LEU LEU C . n A 1 6 GLY 6 6 6 GLY GLY C . n A 1 7 LYS 7 7 7 LYS LYS C . n A 1 8 LYS 8 8 8 LYS LYS C . n A 1 9 GLY 9 9 9 GLY GLY C . n A 1 10 ASP 10 10 10 ASP ASP C . n A 1 11 THR 11 11 11 THR THR C . n A 1 12 VAL 12 12 12 VAL VAL C . n A 1 13 GLU 13 13 13 GLU GLU C . n A 1 14 LEU 14 14 14 LEU LEU C . n A 1 15 THR 15 15 15 THR THR C . n A 1 16 CYS 16 16 16 CYS CYS C . n A 1 17 THR 17 17 17 THR THR C . n A 1 18 ALA 18 18 18 ALA ALA C . n A 1 19 SER 19 19 19 SER SER C . n A 1 20 GLN 20 20 20 GLN GLN C . n A 1 21 LYS 21 21 21 LYS LYS C . n A 1 22 LYS 22 22 22 LYS LYS C . n A 1 23 SER 23 23 23 SER SER C . n A 1 24 ILE 24 24 24 ILE ILE C . n A 1 25 GLN 25 25 25 GLN GLN C . n A 1 26 PHE 26 26 26 PHE PHE C . n A 1 27 HIS 27 27 27 HIS HIS C . n A 1 28 TRP 28 28 28 TRP TRP C . n A 1 29 LYS 29 29 29 LYS LYS C . n A 1 30 ASN 30 30 30 ASN ASN C . n A 1 31 SER 31 31 31 SER SER C . n A 1 32 ASN 32 32 32 ASN ASN C . n A 1 33 GLN 33 33 33 GLN GLN C . n A 1 34 ILE 34 34 34 ILE ILE C . n A 1 35 LYS 35 35 35 LYS LYS C . n A 1 36 ILE 36 36 36 ILE ILE C . n A 1 37 LEU 37 37 37 LEU LEU C . n A 1 38 GLY 38 38 38 GLY GLY C . n A 1 39 ASN 39 39 39 ASN ASN C . n A 1 40 GLN 40 40 40 GLN GLN C . n A 1 41 GLY 41 41 41 GLY GLY C . n A 1 42 SER 42 42 42 SER SER C . n A 1 43 PHE 43 43 43 PHE PHE C . n A 1 44 LEU 44 44 44 LEU LEU C . n A 1 45 THR 45 45 45 THR THR C . n A 1 46 LYS 46 46 46 LYS LYS C . n A 1 47 GLY 47 47 47 GLY GLY C . n A 1 48 PRO 48 48 48 PRO PRO C . n A 1 49 SER 49 49 49 SER SER C . n A 1 50 LYS 50 50 50 LYS LYS C . n A 1 51 LEU 51 51 51 LEU LEU C . n A 1 52 ASN 52 52 52 ASN ASN C . n A 1 53 ASP 53 53 53 ASP ASP C . n A 1 54 ARG 54 54 54 ARG ARG C . n A 1 55 ALA 55 55 55 ALA ALA C . n A 1 56 ASP 56 56 56 ASP ASP C . n A 1 57 SER 57 57 57 SER SER C . n A 1 58 ARG 58 58 58 ARG ARG C . n A 1 59 ARG 59 59 59 ARG ARG C . n A 1 60 SER 60 60 60 SER SER C . n A 1 61 LEU 61 61 61 LEU LEU C . n A 1 62 TRP 62 62 62 TRP TRP C . n A 1 63 ASP 63 63 63 ASP ASP C . n A 1 64 GLN 64 64 64 GLN GLN C . n A 1 65 GLY 65 65 65 GLY GLY C . n A 1 66 ASN 66 66 66 ASN ASN C . n A 1 67 PHE 67 67 67 PHE PHE C . n A 1 68 PRO 68 68 68 PRO PRO C . n A 1 69 LEU 69 69 69 LEU LEU C . n A 1 70 ILE 70 70 70 ILE ILE C . n A 1 71 ILE 71 71 71 ILE ILE C . n A 1 72 LYS 72 72 72 LYS LYS C . n A 1 73 ASN 73 73 73 ASN ASN C . n A 1 74 LEU 74 74 74 LEU LEU C . n A 1 75 LYS 75 75 75 LYS LYS C . n A 1 76 ILE 76 76 76 ILE ILE C . n A 1 77 GLU 77 77 77 GLU GLU C . n A 1 78 ASP 78 78 78 ASP ASP C . n A 1 79 SER 79 79 79 SER SER C . n A 1 80 ASP 80 80 80 ASP ASP C . n A 1 81 THR 81 81 81 THR THR C . n A 1 82 TYR 82 82 82 TYR TYR C . n A 1 83 ILE 83 83 83 ILE ILE C . n A 1 84 CYS 84 84 84 CYS CYS C . n A 1 85 GLU 85 85 85 GLU GLU C . n A 1 86 VAL 86 86 86 VAL VAL C . n A 1 87 GLU 87 87 87 GLU GLU C . n A 1 88 ASP 88 88 88 ASP ASP C . n A 1 89 GLN 89 89 89 GLN GLN C . n A 1 90 LYS 90 90 90 LYS LYS C . n A 1 91 GLU 91 91 91 GLU GLU C . n A 1 92 GLU 92 92 92 GLU GLU C . n A 1 93 VAL 93 93 93 VAL VAL C . n A 1 94 GLN 94 94 94 GLN GLN C . n A 1 95 LEU 95 95 95 LEU LEU C . n A 1 96 LEU 96 96 96 LEU LEU C . n A 1 97 VAL 97 97 97 VAL VAL C . n A 1 98 PHE 98 98 98 PHE PHE C . n A 1 99 GLY 99 99 99 GLY GLY C . n A 1 100 LEU 100 100 100 LEU LEU C . n A 1 101 THR 101 101 101 THR THR C . n A 1 102 ALA 102 102 102 ALA ALA C . n A 1 103 ASN 103 103 103 ASN ASN C . n A 1 104 SER 104 104 104 SER SER C . n A 1 105 ASP 105 105 105 ASP ASP C . n A 1 106 THR 106 106 106 THR THR C . n A 1 107 HIS 107 107 107 HIS HIS C . n A 1 108 LEU 108 108 108 LEU LEU C . n A 1 109 LEU 109 109 109 LEU LEU C . n A 1 110 GLN 110 110 110 GLN GLN C . n A 1 111 GLY 111 111 111 GLY GLY C . n A 1 112 GLN 112 112 112 GLN GLN C . n A 1 113 SER 113 113 113 SER SER C . n A 1 114 LEU 114 114 114 LEU LEU C . n A 1 115 THR 115 115 115 THR THR C . n A 1 116 LEU 116 116 116 LEU LEU C . n A 1 117 THR 117 117 117 THR THR C . n A 1 118 LEU 118 118 118 LEU LEU C . n A 1 119 GLU 119 119 119 GLU GLU C . n A 1 120 SER 120 120 120 SER SER C . n A 1 121 PRO 121 121 121 PRO PRO C . n A 1 122 PRO 122 122 122 PRO PRO C . n A 1 123 GLY 123 123 123 GLY GLY C . n A 1 124 SER 124 124 124 SER SER C . n A 1 125 SER 125 125 125 SER SER C . n A 1 126 PRO 126 126 126 PRO PRO C . n A 1 127 SER 127 127 127 SER SER C . n A 1 128 VAL 128 128 128 VAL VAL C . n A 1 129 GLN 129 129 129 GLN GLN C . n A 1 130 CYS 130 130 130 CYS CYS C . n A 1 131 ARG 131 131 131 ARG ARG C . n A 1 132 SER 132 132 132 SER SER C . n A 1 133 PRO 133 133 133 PRO PRO C . n A 1 134 ARG 134 134 134 ARG ARG C . n A 1 135 GLY 135 135 135 GLY GLY C . n A 1 136 LYS 136 136 136 LYS LYS C . n A 1 137 ASN 137 137 137 ASN ASN C . n A 1 138 ILE 138 138 138 ILE ILE C . n A 1 139 GLN 139 139 139 GLN GLN C . n A 1 140 GLY 140 140 140 GLY GLY C . n A 1 141 GLY 141 141 141 GLY GLY C . n A 1 142 LYS 142 142 142 LYS LYS C . n A 1 143 THR 143 143 143 THR THR C . n A 1 144 LEU 144 144 144 LEU LEU C . n A 1 145 SER 145 145 145 SER SER C . n A 1 146 VAL 146 146 146 VAL VAL C . n A 1 147 SER 147 147 147 SER SER C . n A 1 148 GLN 148 148 148 GLN GLN C . n A 1 149 LEU 149 149 149 LEU LEU C . n A 1 150 GLU 150 150 150 GLU GLU C . n A 1 151 LEU 151 151 151 LEU LEU C . n A 1 152 GLN 152 152 152 GLN GLN C . n A 1 153 ASP 153 153 153 ASP ASP C . n A 1 154 SER 154 154 154 SER SER C . n A 1 155 GLY 155 155 155 GLY GLY C . n A 1 156 THR 156 156 156 THR THR C . n A 1 157 TRP 157 157 157 TRP TRP C . n A 1 158 THR 158 158 158 THR THR C . n A 1 159 CYS 159 159 159 CYS CYS C . n A 1 160 THR 160 160 160 THR THR C . n A 1 161 VAL 161 161 161 VAL VAL C . n A 1 162 LEU 162 162 162 LEU LEU C . n A 1 163 GLN 163 163 163 GLN GLN C . n A 1 164 ASN 164 164 164 ASN ASN C . n A 1 165 GLN 165 165 165 GLN GLN C . n A 1 166 LYS 166 166 166 LYS LYS C . n A 1 167 LYS 167 167 167 LYS LYS C . n A 1 168 VAL 168 168 168 VAL VAL C . n A 1 169 GLU 169 169 169 GLU GLU C . n A 1 170 PHE 170 170 170 PHE PHE C . n A 1 171 LYS 171 171 171 LYS LYS C . n A 1 172 ILE 172 172 172 ILE ILE C . n A 1 173 ASP 173 173 173 ASP ASP C . n A 1 174 ILE 174 174 174 ILE ILE C . n A 1 175 VAL 175 175 175 VAL VAL C . n A 1 176 VAL 176 176 176 VAL VAL C . n A 1 177 LEU 177 177 ? ? ? C . n A 1 178 ALA 178 178 ? ? ? C . n A 1 179 PHE 179 179 ? ? ? C . n A 1 180 GLN 180 180 ? ? ? C . n A 1 181 LYS 181 181 ? ? ? C . n A 1 182 ALA 182 182 ? ? ? C . n A 1 183 ILE 183 183 ? ? ? C . n A 1 184 ASP 184 184 ? ? ? C . n A 1 185 GLY 185 185 ? ? ? C . n A 1 186 ARG 186 186 ? ? ? C . n A 1 187 HIS 187 187 ? ? ? C . n A 1 188 HIS 188 188 ? ? ? C . n A 1 189 HIS 189 189 ? ? ? C . n A 1 190 HIS 190 190 ? ? ? C . n A 1 191 HIS 191 191 ? ? ? C . n A 1 192 HIS 192 192 ? ? ? C . n B 2 1 GLU 1 82 ? ? ? G . n B 2 2 ILE 2 83 ? ? ? G . n B 2 3 VAL 3 84 ? ? ? G . n B 2 4 LEU 4 85 85 LEU LEU G . n B 2 5 GLU 5 86 86 GLU GLU G . n B 2 6 ASN 6 87 87 ASN ASN G . n B 2 7 VAL 7 88 88 VAL VAL G . n B 2 8 ILE 8 89 89 ILE ILE G . n B 2 9 GLU 9 90 90 GLU GLU G . n B 2 10 ASN 10 91 91 ASN ASN G . n B 2 11 PHE 11 92 92 PHE PHE G . n B 2 12 ASN 12 93 93 ASN ASN G . n B 2 13 MET 13 94 94 MET MET G . n B 2 14 TRP 14 95 95 TRP TRP G . n B 2 15 LYS 15 96 96 LYS LYS G . n B 2 16 ASN 16 97 97 ASN ASN G . n B 2 17 ASP 17 98 98 ASP ASP G . n B 2 18 MET 18 99 99 MET MET G . n B 2 19 VAL 19 100 100 VAL VAL G . n B 2 20 ASP 20 101 101 ASP ASP G . n B 2 21 GLN 21 102 102 GLN GLN G . n B 2 22 MET 22 103 103 MET MET G . n B 2 23 HIS 23 104 104 HIS HIS G . n B 2 24 GLN 24 105 105 GLN GLN G . n B 2 25 ASP 25 106 106 ASP ASP G . n B 2 26 ILE 26 107 107 ILE ILE G . n B 2 27 ILE 27 108 108 ILE ILE G . n B 2 28 SER 28 109 109 SER SER G . n B 2 29 LEU 29 110 110 LEU LEU G . n B 2 30 TRP 30 111 111 TRP TRP G . n B 2 31 ASP 31 112 112 ASP ASP G . n B 2 32 GLN 32 113 113 GLN GLN G . n B 2 33 SER 33 114 114 SER SER G . n B 2 34 LEU 34 115 115 LEU LEU G . n B 2 35 LYS 35 116 116 LYS LYS G . n B 2 36 PRO 36 117 117 PRO PRO G . n B 2 37 CYS 37 118 118 CYS CYS G . n B 2 38 VAL 38 119 119 VAL VAL G . n B 2 39 LYS 39 120 120 LYS LYS G . n B 2 40 LEU 40 121 121 LEU LEU G . n B 2 41 THR 41 122 122 THR THR G . n B 2 42 PRO 42 123 123 PRO PRO G . n B 2 43 LEU 43 185 ? ? ? G . n B 2 44 CYS 44 186 ? ? ? G . n B 2 45 VAL 45 187 ? ? ? G . n B 2 46 GLY 46 188 ? ? ? G . n B 2 47 ALA 47 189 ? ? ? G . n B 2 48 GLY 48 190 ? ? ? G . n B 2 49 ASN 49 191 ? ? ? G . n B 2 50 CYS 50 192 ? ? ? G . n B 2 51 ASN 51 193 193 ASN ASN G . n B 2 52 THR 52 194 194 THR THR G . n B 2 53 SER 53 195 195 SER SER G . n B 2 54 THR 54 196 196 THR THR G . n B 2 55 ILE 55 197 197 ILE ILE G . n B 2 56 ALA 56 198 198 ALA ALA G . n B 2 57 GLN 57 199 199 GLN GLN G . n B 2 58 ALA 58 200 200 ALA ALA G . n B 2 59 CYS 59 201 201 CYS CYS G . n B 2 60 PRO 60 202 202 PRO PRO G . n B 2 61 LYS 61 203 203 LYS LYS G . n B 2 62 VAL 62 204 204 VAL VAL G . n B 2 63 SER 63 205 205 SER SER G . n B 2 64 PHE 64 206 206 PHE PHE G . n B 2 65 ASP 65 207 207 ASP ASP G . n B 2 66 PRO 66 208 208 PRO PRO G . n B 2 67 ILE 67 209 209 ILE ILE G . n B 2 68 PRO 68 210 210 PRO PRO G . n B 2 69 ILE 69 211 211 ILE ILE G . n B 2 70 HIS 70 212 212 HIS HIS G . n B 2 71 TYR 71 213 213 TYR TYR G . n B 2 72 CYS 72 214 214 CYS CYS G . n B 2 73 ALA 73 215 215 ALA ALA G . n B 2 74 PRO 74 216 216 PRO PRO G . n B 2 75 ALA 75 217 217 ALA ALA G . n B 2 76 GLY 76 218 218 GLY GLY G . n B 2 77 TYR 77 219 219 TYR TYR G . n B 2 78 ALA 78 220 220 ALA ALA G . n B 2 79 ILE 79 221 221 ILE ILE G . n B 2 80 LEU 80 222 222 LEU LEU G . n B 2 81 LYS 81 223 223 LYS LYS G . n B 2 82 CYS 82 224 224 CYS CYS G . n B 2 83 ASN 83 225 225 ASN ASN G . n B 2 84 ASP 84 226 226 ASP ASP G . n B 2 85 LYS 85 227 227 LYS LYS G . n B 2 86 THR 86 228 228 THR THR G . n B 2 87 PHE 87 229 229 PHE PHE G . n B 2 88 ASN 88 230 230 ASN ASN G . n B 2 89 GLY 89 231 231 GLY GLY G . n B 2 90 ILE 90 232 232 ILE ILE G . n B 2 91 GLY 91 233 233 GLY GLY G . n B 2 92 PRO 92 234 234 PRO PRO G . n B 2 93 CYS 93 235 235 CYS CYS G . n B 2 94 ASN 94 236 236 ASN ASN G . n B 2 95 ASN 95 237 237 ASN ASN G . n B 2 96 VAL 96 238 238 VAL VAL G . n B 2 97 SER 97 239 239 SER SER G . n B 2 98 THR 98 240 240 THR THR G . n B 2 99 VAL 99 241 241 VAL VAL G . n B 2 100 GLN 100 242 242 GLN GLN G . n B 2 101 CYS 101 243 243 CYS CYS G . n B 2 102 THR 102 244 244 THR THR G . n B 2 103 HIS 103 245 245 HIS HIS G . n B 2 104 GLY 104 246 246 GLY GLY G . n B 2 105 ILE 105 247 247 ILE ILE G . n B 2 106 LYS 106 248 248 LYS LYS G . n B 2 107 PRO 107 249 249 PRO PRO G . n B 2 108 VAL 108 250 250 VAL VAL G . n B 2 109 VAL 109 251 251 VAL VAL G . n B 2 110 SER 110 252 252 SER SER G . n B 2 111 THR 111 253 253 THR THR G . n B 2 112 GLN 112 254 254 GLN GLN G . n B 2 113 LEU 113 255 255 LEU LEU G . n B 2 114 LEU 114 256 256 LEU LEU G . n B 2 115 LEU 115 257 257 LEU LEU G . n B 2 116 ASN 116 258 258 ASN ASN G . n B 2 117 GLY 117 259 259 GLY GLY G . n B 2 118 SER 118 260 260 SER SER G . n B 2 119 LEU 119 261 261 LEU LEU G . n B 2 120 ALA 120 262 262 ALA ALA G . n B 2 121 GLU 121 263 263 GLU GLU G . n B 2 122 GLU 122 264 264 GLU GLU G . n B 2 123 GLU 123 265 265 GLU GLU G . n B 2 124 VAL 124 266 266 VAL VAL G . n B 2 125 VAL 125 267 267 VAL VAL G . n B 2 126 ILE 126 268 268 ILE ILE G . n B 2 127 ARG 127 269 269 ARG ARG G . n B 2 128 SER 128 270 270 SER SER G . n B 2 129 GLU 129 271 271 GLU GLU G . n B 2 130 ASN 130 272 272 ASN ASN G . n B 2 131 ILE 131 273 273 ILE ILE G . n B 2 132 SER 132 274 274 SER SER G . n B 2 133 ASN 133 275 275 ASN ASN G . n B 2 134 ASN 134 276 276 ASN ASN G . n B 2 135 VAL 135 277 277 VAL VAL G . n B 2 136 LYS 136 278 278 LYS LYS G . n B 2 137 THR 137 279 279 THR THR G . n B 2 138 ILE 138 280 280 ILE ILE G . n B 2 139 ILE 139 281 281 ILE ILE G . n B 2 140 VAL 140 282 282 VAL VAL G . n B 2 141 HIS 141 283 283 HIS HIS G . n B 2 142 LEU 142 284 284 LEU LEU G . n B 2 143 THR 143 285 285 THR THR G . n B 2 144 GLU 144 286 286 GLU GLU G . n B 2 145 SER 145 287 287 SER SER G . n B 2 146 VAL 146 288 288 VAL VAL G . n B 2 147 ASN 147 289 289 ASN ASN G . n B 2 148 ILE 148 290 290 ILE ILE G . n B 2 149 THR 149 291 291 THR THR G . n B 2 150 CYS 150 292 292 CYS CYS G . n B 2 151 ILE 151 293 293 ILE ILE G . n B 2 152 GLY 152 294 294 GLY GLY G . n B 2 153 ALA 153 323 ? ? ? G . n B 2 154 GLY 154 324 324 GLY GLY G . n B 2 155 HIS 155 325 325 HIS HIS G . n B 2 156 CYS 156 326 326 CYS CYS G . n B 2 157 ASN 157 327 327 ASN ASN G . n B 2 158 ILE 158 328 328 ILE ILE G . n B 2 159 ASN 159 329 329 ASN ASN G . n B 2 160 GLU 160 330 330 GLU GLU G . n B 2 161 LYS 161 331 331 LYS LYS G . n B 2 162 ALA 162 332 332 ALA ALA G . n B 2 163 TRP 163 333 333 TRP TRP G . n B 2 164 ASN 164 334 334 ASN ASN G . n B 2 165 GLU 165 335 335 GLU GLU G . n B 2 166 THR 166 336 336 THR THR G . n B 2 167 LEU 167 337 337 LEU LEU G . n B 2 168 LYS 168 338 338 LYS LYS G . n B 2 169 LYS 169 339 339 LYS LYS G . n B 2 170 VAL 170 340 340 VAL VAL G . n B 2 171 VAL 171 341 341 VAL VAL G . n B 2 172 GLU 172 342 342 GLU GLU G . n B 2 173 LYS 173 343 343 LYS LYS G . n B 2 174 LEU 174 344 344 LEU LEU G . n B 2 175 VAL 175 345 345 VAL VAL G . n B 2 176 LYS 176 346 346 LYS LYS G . n B 2 177 TYR 177 347 347 TYR TYR G . n B 2 178 PHE 178 348 348 PHE PHE G . n B 2 179 PRO 179 349 349 PRO PRO G . n B 2 180 ASN 180 350 350 ASN ASN G . n B 2 181 LYS 181 351 351 LYS LYS G . n B 2 182 THR 182 352 352 THR THR G . n B 2 183 ILE 183 353 353 ILE ILE G . n B 2 184 GLU 184 354 354 GLU GLU G . n B 2 185 PHE 185 355 355 PHE PHE G . n B 2 186 ALA 186 356 356 ALA ALA G . n B 2 187 PRO 187 357 357 PRO PRO G . n B 2 188 PRO 188 358 358 PRO PRO G . n B 2 189 VAL 189 359 359 VAL VAL G . n B 2 190 GLY 190 360 360 GLY GLY G . n B 2 191 GLY 191 361 361 GLY GLY G . n B 2 192 ASP 192 362 362 ASP ASP G . n B 2 193 LEU 193 363 363 LEU LEU G . n B 2 194 GLU 194 364 364 GLU GLU G . n B 2 195 ILE 195 365 365 ILE ILE G . n B 2 196 THR 196 366 366 THR THR G . n B 2 197 THR 197 367 367 THR THR G . n B 2 198 HIS 198 368 368 HIS HIS G . n B 2 199 SER 199 369 369 SER SER G . n B 2 200 PHE 200 370 370 PHE PHE G . n B 2 201 ASN 201 371 371 ASN ASN G . n B 2 202 CYS 202 372 372 CYS CYS G . n B 2 203 GLY 203 373 373 GLY GLY G . n B 2 204 GLY 204 374 374 GLY GLY G . n B 2 205 GLU 205 375 375 GLU GLU G . n B 2 206 PHE 206 376 376 PHE PHE G . n B 2 207 PHE 207 377 377 PHE PHE G . n B 2 208 TYR 208 378 378 TYR TYR G . n B 2 209 CYS 209 379 379 CYS CYS G . n B 2 210 ASN 210 380 380 ASN ASN G . n B 2 211 THR 211 381 381 THR THR G . n B 2 212 THR 212 382 382 THR THR G . n B 2 213 LYS 213 383 383 LYS LYS G . n B 2 214 LEU 214 384 384 LEU LEU G . n B 2 215 PHE 215 385 385 PHE PHE G . n B 2 216 ASN 216 386 386 ASN ASN G . n B 2 217 SER 217 387 387 SER SER G . n B 2 218 ILE 218 388 388 ILE ILE G . n B 2 219 HIS 219 389 389 HIS HIS G . n B 2 220 ASN 220 390 390 ASN ASN G . n B 2 221 SER 221 391 391 SER SER G . n B 2 222 THR 222 392 ? ? ? G . n B 2 223 ASP 223 393 ? ? ? G . n B 2 224 SER 224 394 ? ? ? G . n B 2 225 THR 225 395 ? ? ? G . n B 2 226 VAL 226 396 ? ? ? G . n B 2 227 ASN 227 397 ? ? ? G . n B 2 228 SER 228 398 ? ? ? G . n B 2 229 THR 229 399 ? ? ? G . n B 2 230 ASP 230 400 ? ? ? G . n B 2 231 SER 231 401 ? ? ? G . n B 2 232 THR 232 402 ? ? ? G . n B 2 233 ALA 233 403 ? ? ? G . n B 2 234 GLU 234 404 ? ? ? G . n B 2 235 THR 235 405 ? ? ? G . n B 2 236 GLY 236 406 ? ? ? G . n B 2 237 ASN 237 407 ? ? ? G . n B 2 238 SER 238 408 ? ? ? G . n B 2 239 THR 239 409 ? ? ? G . n B 2 240 ASN 240 410 ? ? ? G . n B 2 241 THR 241 411 ? ? ? G . n B 2 242 ASN 242 412 ? ? ? G . n B 2 243 ILE 243 413 413 ILE ILE G . n B 2 244 THR 244 414 414 THR THR G . n B 2 245 LEU 245 415 415 LEU LEU G . n B 2 246 PRO 246 416 416 PRO PRO G . n B 2 247 CYS 247 417 417 CYS CYS G . n B 2 248 ARG 248 418 418 ARG ARG G . n B 2 249 ILE 249 419 419 ILE ILE G . n B 2 250 ARG 250 420 420 ARG ARG G . n B 2 251 GLN 251 421 421 GLN GLN G . n B 2 252 ILE 252 422 422 ILE ILE G . n B 2 253 ILE 253 423 423 ILE ILE G . n B 2 254 ASN 254 424 424 ASN ASN G . n B 2 255 MET 255 425 425 MET MET G . n B 2 256 TRP 256 426 426 TRP TRP G . n B 2 257 GLN 257 427 427 GLN GLN G . n B 2 258 GLU 258 428 428 GLU GLU G . n B 2 259 VAL 259 429 429 VAL VAL G . n B 2 260 GLY 260 430 430 GLY GLY G . n B 2 261 ARG 261 431 431 ARG ARG G . n B 2 262 ALA 262 432 432 ALA ALA G . n B 2 263 MET 263 433 433 MET MET G . n B 2 264 TYR 264 434 434 TYR TYR G . n B 2 265 ALA 265 435 435 ALA ALA G . n B 2 266 PRO 266 436 436 PRO PRO G . n B 2 267 PRO 267 437 437 PRO PRO G . n B 2 268 SER 268 438 438 SER SER G . n B 2 269 LYS 269 439 439 LYS LYS G . n B 2 270 GLY 270 440 440 GLY GLY G . n B 2 271 ASN 271 441 441 ASN ASN G . n B 2 272 ILE 272 442 442 ILE ILE G . n B 2 273 THR 273 443 443 THR THR G . n B 2 274 CYS 274 444 444 CYS CYS G . n B 2 275 ILE 275 445 445 ILE ILE G . n B 2 276 SER 276 446 446 SER SER G . n B 2 277 ASP 277 447 447 ASP ASP G . n B 2 278 ILE 278 448 448 ILE ILE G . n B 2 279 THR 279 449 449 THR THR G . n B 2 280 GLY 280 450 450 GLY GLY G . n B 2 281 LEU 281 451 451 LEU LEU G . n B 2 282 LEU 282 452 452 LEU LEU G . n B 2 283 LEU 283 453 453 LEU LEU G . n B 2 284 THR 284 454 454 THR THR G . n B 2 285 ARG 285 455 455 ARG ARG G . n B 2 286 ASP 286 456 456 ASP ASP G . n B 2 287 GLY 287 457 457 GLY GLY G . n B 2 288 GLY 288 458 458 GLY GLY G . n B 2 289 GLU 289 459 459 GLU GLU G . n B 2 290 ASN 290 460 460 ASN ASN G . n B 2 291 LYS 291 461 461 LYS LYS G . n B 2 292 THR 292 462 462 THR THR G . n B 2 293 GLU 293 463 463 GLU GLU G . n B 2 294 ASN 294 464 464 ASN ASN G . n B 2 295 ASN 295 465 465 ASN ASN G . n B 2 296 ASP 296 466 466 ASP ASP G . n B 2 297 THR 297 467 467 THR THR G . n B 2 298 GLU 298 468 468 GLU GLU G . n B 2 299 ILE 299 469 469 ILE ILE G . n B 2 300 PHE 300 470 470 PHE PHE G . n B 2 301 ARG 301 471 471 ARG ARG G . n B 2 302 PRO 302 472 472 PRO PRO G . n B 2 303 GLY 303 473 473 GLY GLY G . n B 2 304 GLY 304 474 474 GLY GLY G . n B 2 305 GLY 305 475 475 GLY GLY G . n B 2 306 ASP 306 476 476 ASP ASP G . n B 2 307 MET 307 477 477 MET MET G . n B 2 308 LYS 308 478 478 LYS LYS G . n B 2 309 ASP 309 479 479 ASP ASP G . n B 2 310 ASN 310 480 480 ASN ASN G . n B 2 311 TRP 311 481 481 TRP TRP G . n B 2 312 ARG 312 482 482 ARG ARG G . n B 2 313 SER 313 483 483 SER SER G . n B 2 314 GLU 314 484 484 GLU GLU G . n B 2 315 LEU 315 485 485 LEU LEU G . n B 2 316 TYR 316 486 486 TYR TYR G . n B 2 317 LYS 317 487 487 LYS LYS G . n B 2 318 TYR 318 488 488 TYR TYR G . n B 2 319 LYS 319 489 489 LYS LYS G . n B 2 320 VAL 320 490 490 VAL VAL G . n B 2 321 VAL 321 491 491 VAL VAL G . n B 2 322 GLU 322 492 492 GLU GLU G . n B 2 323 ILE 323 493 493 ILE ILE G . n B 2 324 LYS 324 494 ? ? ? G . n B 2 325 SER 325 495 ? ? ? G . n B 2 326 GLY 326 496 ? ? ? G . n B 2 327 HIS 327 497 ? ? ? G . n B 2 328 HIS 328 498 ? ? ? G . n B 2 329 HIS 329 499 ? ? ? G . n B 2 330 HIS 330 500 ? ? ? G . n B 2 331 HIS 331 501 ? ? ? G . n B 2 332 HIS 332 502 ? ? ? G . n C 3 1 GLN 1 1 1 GLN GLN H . n C 3 2 VAL 2 2 2 VAL VAL H . n C 3 3 GLN 3 3 3 GLN GLN H . n C 3 4 VAL 4 4 4 VAL VAL H . n C 3 5 VAL 5 5 5 VAL VAL H . n C 3 6 GLN 6 6 6 GLN GLN H . n C 3 7 SER 7 7 7 SER SER H . n C 3 8 GLY 8 8 8 GLY GLY H . n C 3 9 ALA 9 9 9 ALA ALA H . n C 3 10 GLU 10 10 10 GLU GLU H . n C 3 11 VAL 11 11 11 VAL VAL H . n C 3 12 ARG 12 12 12 ARG ARG H . n C 3 13 LYS 13 13 13 LYS LYS H . n C 3 14 PRO 14 14 14 PRO PRO H . n C 3 15 GLY 15 15 15 GLY GLY H . n C 3 16 ALA 16 16 16 ALA ALA H . n C 3 17 SER 17 17 17 SER SER H . n C 3 18 VAL 18 18 18 VAL VAL H . n C 3 19 LYS 19 19 19 LYS LYS H . n C 3 20 VAL 20 20 20 VAL VAL H . n C 3 21 SER 21 21 21 SER SER H . n C 3 22 CYS 22 22 22 CYS CYS H . n C 3 23 LYS 23 23 23 LYS LYS H . n C 3 24 VAL 24 24 24 VAL VAL H . n C 3 25 SER 25 25 25 SER SER H . n C 3 26 GLY 26 26 26 GLY GLY H . n C 3 27 PHE 27 27 27 PHE PHE H . n C 3 28 THR 28 28 28 THR THR H . n C 3 29 LEU 29 29 29 LEU LEU H . n C 3 30 THR 30 30 30 THR THR H . n C 3 31 GLY 31 31 31 GLY GLY H . n C 3 32 LEU 32 32 32 LEU LEU H . n C 3 33 SER 33 33 33 SER SER H . n C 3 34 ILE 34 34 34 ILE ILE H . n C 3 35 HIS 35 35 35 HIS HIS H . n C 3 36 TRP 36 36 36 TRP TRP H . n C 3 37 VAL 37 37 37 VAL VAL H . n C 3 38 ARG 38 38 38 ARG ARG H . n C 3 39 GLN 39 39 39 GLN GLN H . n C 3 40 ALA 40 40 40 ALA ALA H . n C 3 41 PRO 41 41 41 PRO PRO H . n C 3 42 GLY 42 42 42 GLY GLY H . n C 3 43 LYS 43 43 43 LYS LYS H . n C 3 44 GLY 44 44 44 GLY GLY H . n C 3 45 LEU 45 45 45 LEU LEU H . n C 3 46 GLU 46 46 46 GLU GLU H . n C 3 47 TRP 47 47 47 TRP TRP H . n C 3 48 MET 48 48 48 MET MET H . n C 3 49 GLY 49 49 49 GLY GLY H . n C 3 50 GLY 50 50 50 GLY GLY H . n C 3 51 PHE 51 51 51 PHE PHE H . n C 3 52 GLY 52 52 52 GLY GLY H . n C 3 53 PRO 53 53 53 PRO PRO H . n C 3 54 GLU 54 54 54 GLU GLU H . n C 3 55 GLU 55 55 55 GLU GLU H . n C 3 56 ASN 56 56 56 ASN ASN H . n C 3 57 GLU 57 57 57 GLU GLU H . n C 3 58 ILE 58 58 58 ILE ILE H . n C 3 59 ILE 59 59 59 ILE ILE H . n C 3 60 TYR 60 60 60 TYR TYR H . n C 3 61 ALA 61 61 61 ALA ALA H . n C 3 62 GLN 62 62 62 GLN GLN H . n C 3 63 LYS 63 63 63 LYS LYS H . n C 3 64 PHE 64 64 64 PHE PHE H . n C 3 65 GLN 65 65 65 GLN GLN H . n C 3 66 GLY 66 66 66 GLY GLY H . n C 3 67 ARG 67 67 67 ARG ARG H . n C 3 68 VAL 68 68 68 VAL VAL H . n C 3 69 SER 69 69 69 SER SER H . n C 3 70 MET 70 70 70 MET MET H . n C 3 71 THR 71 71 71 THR THR H . n C 3 72 GLU 72 72 72 GLU GLU H . n C 3 73 ASP 73 73 73 ASP ASP H . n C 3 74 THR 74 74 74 THR THR H . n C 3 75 SER 75 75 75 SER SER H . n C 3 76 THR 76 76 76 THR THR H . n C 3 77 ASN 77 77 77 ASN ASN H . n C 3 78 THR 78 78 78 THR THR H . n C 3 79 ALA 79 79 79 ALA ALA H . n C 3 80 TYR 80 80 80 TYR TYR H . n C 3 81 MET 81 81 81 MET MET H . n C 3 82 GLU 82 82 82 GLU GLU H . n C 3 83 LEU 83 83 83 LEU LEU H . n C 3 84 SER 84 84 84 SER SER H . n C 3 85 SER 85 85 85 SER SER H . n C 3 86 LEU 86 86 86 LEU LEU H . n C 3 87 ARG 87 87 87 ARG ARG H . n C 3 88 SER 88 88 88 SER SER H . n C 3 89 GLU 89 89 89 GLU GLU H . n C 3 90 ASP 90 90 90 ASP ASP H . n C 3 91 THR 91 91 91 THR THR H . n C 3 92 ALA 92 92 92 ALA ALA H . n C 3 93 VAL 93 93 93 VAL VAL H . n C 3 94 TYR 94 94 94 TYR TYR H . n C 3 95 TYR 95 95 95 TYR TYR H . n C 3 96 CYS 96 96 96 CYS CYS H . n C 3 97 ALA 97 97 97 ALA ALA H . n C 3 98 THR 98 98 98 THR THR H . n C 3 99 GLY 99 99 99 GLY GLY H . n C 3 100 GLY 100 100 100 GLY GLY H . n C 3 101 ASN 101 101 101 ASN ASN H . n C 3 102 TYR 102 102 102 TYR TYR H . n C 3 103 TYR 103 103 103 TYR TYR H . n C 3 104 ASN 104 104 104 ASN ASN H . n C 3 105 LEU 105 105 105 LEU LEU H . n C 3 106 TRP 106 106 106 TRP TRP H . n C 3 107 THR 107 107 107 THR THR H . n C 3 108 GLY 108 108 108 GLY GLY H . n C 3 109 TYR 109 109 109 TYR TYR H . n C 3 110 TYR 110 110 110 TYR TYR H . n C 3 111 PRO 111 111 111 PRO PRO H . n C 3 112 LEU 112 112 112 LEU LEU H . n C 3 113 ALA 113 113 113 ALA ALA H . n C 3 114 TYR 114 114 114 TYR TYR H . n C 3 115 TRP 115 115 115 TRP TRP H . n C 3 116 GLY 116 116 116 GLY GLY H . n C 3 117 GLN 117 117 117 GLN GLN H . n C 3 118 GLY 118 118 118 GLY GLY H . n C 3 119 THR 119 119 119 THR THR H . n C 3 120 LEU 120 120 120 LEU LEU H . n C 3 121 VAL 121 121 121 VAL VAL H . n C 3 122 THR 122 122 122 THR THR H . n C 3 123 VAL 123 123 123 VAL VAL H . n C 3 124 SER 124 124 124 SER SER H . n C 3 125 SER 125 125 125 SER SER H . n C 3 126 ALA 126 126 126 ALA ALA H . n C 3 127 SER 127 127 127 SER SER H . n C 3 128 THR 128 128 128 THR THR H . n C 3 129 LYS 129 129 129 LYS LYS H . n C 3 130 GLY 130 130 130 GLY GLY H . n C 3 131 PRO 131 131 131 PRO PRO H . n C 3 132 SER 132 132 132 SER SER H . n C 3 133 VAL 133 133 133 VAL VAL H . n C 3 134 PHE 134 134 134 PHE PHE H . n C 3 135 PRO 135 135 135 PRO PRO H . n C 3 136 LEU 136 136 136 LEU LEU H . n C 3 137 ALA 137 137 137 ALA ALA H . n C 3 138 PRO 138 138 138 PRO PRO H . n C 3 139 SER 139 139 139 SER SER H . n C 3 140 SER 140 140 140 SER SER H . n C 3 141 LYS 141 141 141 LYS LYS H . n C 3 142 SER 142 142 142 SER SER H . n C 3 143 THR 143 143 143 THR THR H . n C 3 144 SER 144 144 144 SER SER H . n C 3 145 GLY 145 145 145 GLY GLY H . n C 3 146 GLY 146 146 146 GLY GLY H . n C 3 147 THR 147 147 147 THR THR H . n C 3 148 ALA 148 148 148 ALA ALA H . n C 3 149 ALA 149 149 149 ALA ALA H . n C 3 150 LEU 150 150 150 LEU LEU H . n C 3 151 GLY 151 151 151 GLY GLY H . n C 3 152 CYS 152 152 152 CYS CYS H . n C 3 153 LEU 153 153 153 LEU LEU H . n C 3 154 VAL 154 154 154 VAL VAL H . n C 3 155 LYS 155 155 155 LYS LYS H . n C 3 156 ASP 156 156 156 ASP ASP H . n C 3 157 TYR 157 157 157 TYR TYR H . n C 3 158 PHE 158 158 158 PHE PHE H . n C 3 159 PRO 159 159 159 PRO PRO H . n C 3 160 GLU 160 160 160 GLU GLU H . n C 3 161 PRO 161 161 161 PRO PRO H . n C 3 162 VAL 162 162 162 VAL VAL H . n C 3 163 THR 163 163 163 THR THR H . n C 3 164 VAL 164 164 164 VAL VAL H . n C 3 165 SER 165 165 165 SER SER H . n C 3 166 TRP 166 166 166 TRP TRP H . n C 3 167 ASN 167 167 167 ASN ASN H . n C 3 168 SER 168 168 168 SER SER H . n C 3 169 GLY 169 169 169 GLY GLY H . n C 3 170 ALA 170 170 170 ALA ALA H . n C 3 171 LEU 171 171 171 LEU LEU H . n C 3 172 THR 172 172 172 THR THR H . n C 3 173 SER 173 173 173 SER SER H . n C 3 174 GLY 174 174 174 GLY GLY H . n C 3 175 VAL 175 175 175 VAL VAL H . n C 3 176 HIS 176 176 176 HIS HIS H . n C 3 177 THR 177 177 177 THR THR H . n C 3 178 PHE 178 178 178 PHE PHE H . n C 3 179 PRO 179 179 179 PRO PRO H . n C 3 180 ALA 180 180 180 ALA ALA H . n C 3 181 VAL 181 181 181 VAL VAL H . n C 3 182 LEU 182 182 182 LEU LEU H . n C 3 183 GLN 183 183 183 GLN GLN H . n C 3 184 SER 184 184 184 SER SER H . n C 3 185 SER 185 185 185 SER SER H . n C 3 186 GLY 186 186 186 GLY GLY H . n C 3 187 LEU 187 187 187 LEU LEU H . n C 3 188 TYR 188 188 188 TYR TYR H . n C 3 189 SER 189 189 189 SER SER H . n C 3 190 LEU 190 190 190 LEU LEU H . n C 3 191 SER 191 191 191 SER SER H . n C 3 192 SER 192 192 192 SER SER H . n C 3 193 VAL 193 193 193 VAL VAL H . n C 3 194 VAL 194 194 194 VAL VAL H . n C 3 195 THR 195 195 195 THR THR H . n C 3 196 VAL 196 196 196 VAL VAL H . n C 3 197 PRO 197 197 197 PRO PRO H . n C 3 198 SER 198 198 198 SER SER H . n C 3 199 SER 199 199 199 SER SER H . n C 3 200 SER 200 200 200 SER SER H . n C 3 201 LEU 201 201 201 LEU LEU H . n C 3 202 GLY 202 202 202 GLY GLY H . n C 3 203 THR 203 203 203 THR THR H . n C 3 204 GLN 204 204 204 GLN GLN H . n C 3 205 THR 205 205 205 THR THR H . n C 3 206 TYR 206 206 206 TYR TYR H . n C 3 207 ILE 207 207 207 ILE ILE H . n C 3 208 CYS 208 208 208 CYS CYS H . n C 3 209 ASN 209 209 209 ASN ASN H . n C 3 210 VAL 210 210 210 VAL VAL H . n C 3 211 ASN 211 211 211 ASN ASN H . n C 3 212 HIS 212 212 212 HIS HIS H . n C 3 213 LYS 213 213 213 LYS LYS H . n C 3 214 PRO 214 214 214 PRO PRO H . n C 3 215 SER 215 215 215 SER SER H . n C 3 216 ASN 216 216 216 ASN ASN H . n C 3 217 THR 217 217 217 THR THR H . n C 3 218 LYS 218 218 218 LYS LYS H . n C 3 219 VAL 219 219 219 VAL VAL H . n C 3 220 ASP 220 220 220 ASP ASP H . n C 3 221 LYS 221 221 221 LYS LYS H . n C 3 222 LYS 222 222 222 LYS LYS H . n C 3 223 VAL 223 223 223 VAL VAL H . n C 3 224 GLU 224 224 224 GLU GLU H . n C 3 225 PRO 225 225 225 PRO PRO H . n C 3 226 LYS 226 226 ? ? ? H . n C 3 227 SER 227 227 ? ? ? H . n C 3 228 CYS 228 228 ? ? ? H . n C 3 229 ASP 229 229 ? ? ? H . n C 3 230 LYS 230 230 ? ? ? H . n C 3 231 THR 231 231 ? ? ? H . n D 4 1 GLN 1 2 ? ? ? L . n D 4 2 SER 2 3 3 SER SER L . n D 4 3 VAL 3 4 4 VAL VAL L . n D 4 4 LEU 4 5 5 LEU LEU L . n D 4 5 THR 5 6 6 THR THR L . n D 4 6 GLN 6 7 7 GLN GLN L . n D 4 7 PRO 7 8 8 PRO PRO L . n D 4 8 PRO 8 9 9 PRO PRO L . n D 4 9 SER 9 10 10 SER SER L . n D 4 10 VAL 10 11 11 VAL VAL L . n D 4 11 SER 11 12 12 SER SER L . n D 4 12 ALA 12 13 13 ALA ALA L . n D 4 13 ALA 13 14 14 ALA ALA L . n D 4 14 PRO 14 15 15 PRO PRO L . n D 4 15 GLY 15 16 16 GLY GLY L . n D 4 16 GLN 16 17 17 GLN GLN L . n D 4 17 LYS 17 18 18 LYS LYS L . n D 4 18 VAL 18 19 19 VAL VAL L . n D 4 19 THR 19 20 20 THR THR L . n D 4 20 ILE 20 21 21 ILE ILE L . n D 4 21 SER 21 22 22 SER SER L . n D 4 22 CYS 22 23 23 CYS CYS L . n D 4 23 SER 23 24 24 SER SER L . n D 4 24 GLY 24 25 25 GLY GLY L . n D 4 25 SER 25 26 26 SER SER L . n D 4 26 SER 26 27 27 SER SER L . n D 4 27 SER 27 28 28 SER SER L . n D 4 28 ASN 28 29 29 ASN ASN L . n D 4 29 ILE 29 30 30 ILE ILE L . n D 4 30 GLY 30 31 31 GLY GLY L . n D 4 31 LYS 31 32 32 LYS LYS L . n D 4 32 ASN 32 33 33 ASN ASN L . n D 4 33 TYR 33 34 34 TYR TYR L . n D 4 34 VAL 34 35 35 VAL VAL L . n D 4 35 SER 35 36 36 SER SER L . n D 4 36 TRP 36 37 37 TRP TRP L . n D 4 37 TYR 37 38 38 TYR TYR L . n D 4 38 GLN 38 39 39 GLN GLN L . n D 4 39 GLN 39 40 40 GLN GLN L . n D 4 40 LEU 40 41 41 LEU LEU L . n D 4 41 PRO 41 42 42 PRO PRO L . n D 4 42 GLY 42 43 43 GLY GLY L . n D 4 43 ALA 43 44 44 ALA ALA L . n D 4 44 ALA 44 45 45 ALA ALA L . n D 4 45 PRO 45 46 46 PRO PRO L . n D 4 46 LYS 46 47 47 LYS LYS L . n D 4 47 LEU 47 48 48 LEU LEU L . n D 4 48 LEU 48 49 49 LEU LEU L . n D 4 49 ILE 49 50 50 ILE ILE L . n D 4 50 PHE 50 51 51 PHE PHE L . n D 4 51 ASP 51 52 52 ASP ASP L . n D 4 52 ASP 52 53 53 ASP ASP L . n D 4 53 THR 53 54 54 THR THR L . n D 4 54 GLN 54 55 55 GLN GLN L . n D 4 55 ARG 55 56 56 ARG ARG L . n D 4 56 PRO 56 57 57 PRO PRO L . n D 4 57 SER 57 58 58 SER SER L . n D 4 58 GLY 58 59 59 GLY GLY L . n D 4 59 ILE 59 60 60 ILE ILE L . n D 4 60 PRO 60 61 61 PRO PRO L . n D 4 61 ASP 61 62 62 ASP ASP L . n D 4 62 ARG 62 63 63 ARG ARG L . n D 4 63 PHE 63 64 64 PHE PHE L . n D 4 64 SER 64 65 65 SER SER L . n D 4 65 GLY 65 66 66 GLY GLY L . n D 4 66 SER 66 67 67 SER SER L . n D 4 67 LYS 67 68 68 LYS LYS L . n D 4 68 SER 68 69 69 SER SER L . n D 4 69 GLY 69 70 70 GLY GLY L . n D 4 70 THR 70 71 71 THR THR L . n D 4 71 SER 71 72 72 SER SER L . n D 4 72 ALA 72 73 73 ALA ALA L . n D 4 73 THR 73 74 74 THR THR L . n D 4 74 LEU 74 75 75 LEU LEU L . n D 4 75 ALA 75 76 76 ALA ALA L . n D 4 76 ILE 76 77 77 ILE ILE L . n D 4 77 THR 77 78 78 THR THR L . n D 4 78 GLY 78 79 79 GLY GLY L . n D 4 79 LEU 79 80 80 LEU LEU L . n D 4 80 GLN 80 81 81 GLN GLN L . n D 4 81 THR 81 82 82 THR THR L . n D 4 82 GLY 82 83 83 GLY GLY L . n D 4 83 ASP 83 84 84 ASP ASP L . n D 4 84 GLU 84 85 85 GLU GLU L . n D 4 85 ALA 85 86 86 ALA ALA L . n D 4 86 ASP 86 87 87 ASP ASP L . n D 4 87 TYR 87 88 88 TYR TYR L . n D 4 88 TYR 88 89 89 TYR TYR L . n D 4 89 CYS 89 90 90 CYS CYS L . n D 4 90 GLY 90 91 91 GLY GLY L . n D 4 91 THR 91 92 92 THR THR L . n D 4 92 TRP 92 93 93 TRP TRP L . n D 4 93 ASP 93 94 94 ASP ASP L . n D 4 94 SER 94 95 95 SER SER L . n D 4 95 SER 95 96 96 SER SER L . n D 4 96 LEU 96 97 97 LEU LEU L . n D 4 97 SER 97 98 98 SER SER L . n D 4 98 THR 98 99 99 THR THR L . n D 4 99 GLY 99 100 100 GLY GLY L . n D 4 100 GLN 100 101 101 GLN GLN L . n D 4 101 LEU 101 102 102 LEU LEU L . n D 4 102 PHE 102 103 103 PHE PHE L . n D 4 103 GLY 103 104 104 GLY GLY L . n D 4 104 GLY 104 105 105 GLY GLY L . n D 4 105 GLY 105 106 106 GLY GLY L . n D 4 106 THR 106 107 107 THR THR L . n D 4 107 LYS 107 108 108 LYS LYS L . n D 4 108 LEU 108 109 109 LEU LEU L . n D 4 109 THR 109 110 110 THR THR L . n D 4 110 VAL 110 111 111 VAL VAL L . n D 4 111 LEU 111 112 112 LEU LEU L . n D 4 112 GLY 112 113 113 GLY GLY L . n D 4 113 GLN 113 114 114 GLN GLN L . n D 4 114 PRO 114 115 115 PRO PRO L . n D 4 115 LYS 115 116 116 LYS LYS L . n D 4 116 ALA 116 117 117 ALA ALA L . n D 4 117 ALA 117 118 118 ALA ALA L . n D 4 118 PRO 118 119 119 PRO PRO L . n D 4 119 SER 119 120 120 SER SER L . n D 4 120 VAL 120 121 121 VAL VAL L . n D 4 121 THR 121 122 122 THR THR L . n D 4 122 LEU 122 123 123 LEU LEU L . n D 4 123 PHE 123 124 124 PHE PHE L . n D 4 124 PRO 124 125 125 PRO PRO L . n D 4 125 PRO 125 126 126 PRO PRO L . n D 4 126 SER 126 127 127 SER SER L . n D 4 127 SER 127 128 128 SER SER L . n D 4 128 GLU 128 129 129 GLU GLU L . n D 4 129 GLU 129 130 130 GLU GLU L . n D 4 130 LEU 130 131 131 LEU LEU L . n D 4 131 GLN 131 132 132 GLN GLN L . n D 4 132 ALA 132 133 133 ALA ALA L . n D 4 133 ASN 133 134 134 ASN ASN L . n D 4 134 LYS 134 135 135 LYS LYS L . n D 4 135 ALA 135 136 136 ALA ALA L . n D 4 136 THR 136 137 137 THR THR L . n D 4 137 LEU 137 138 138 LEU LEU L . n D 4 138 VAL 138 139 139 VAL VAL L . n D 4 139 CYS 139 140 140 CYS CYS L . n D 4 140 LEU 140 141 141 LEU LEU L . n D 4 141 ILE 141 142 142 ILE ILE L . n D 4 142 SER 142 143 143 SER SER L . n D 4 143 ASP 143 144 144 ASP ASP L . n D 4 144 PHE 144 145 145 PHE PHE L . n D 4 145 TYR 145 146 146 TYR TYR L . n D 4 146 PRO 146 147 147 PRO PRO L . n D 4 147 GLY 147 148 148 GLY GLY L . n D 4 148 ALA 148 149 149 ALA ALA L . n D 4 149 VAL 149 150 150 VAL VAL L . n D 4 150 THR 150 151 151 THR THR L . n D 4 151 VAL 151 152 152 VAL VAL L . n D 4 152 ALA 152 153 153 ALA ALA L . n D 4 153 TRP 153 154 154 TRP TRP L . n D 4 154 LYS 154 155 155 LYS LYS L . n D 4 155 ALA 155 156 156 ALA ALA L . n D 4 156 ASP 156 157 157 ASP ASP L . n D 4 157 SER 157 158 158 SER SER L . n D 4 158 SER 158 159 159 SER SER L . n D 4 159 PRO 159 160 160 PRO PRO L . n D 4 160 VAL 160 161 161 VAL VAL L . n D 4 161 LYS 161 162 162 LYS LYS L . n D 4 162 ALA 162 163 163 ALA ALA L . n D 4 163 GLY 163 164 164 GLY GLY L . n D 4 164 VAL 164 165 165 VAL VAL L . n D 4 165 GLU 165 166 166 GLU GLU L . n D 4 166 THR 166 167 167 THR THR L . n D 4 167 THR 167 168 168 THR THR L . n D 4 168 THR 168 169 169 THR THR L . n D 4 169 PRO 169 170 170 PRO PRO L . n D 4 170 SER 170 171 171 SER SER L . n D 4 171 LYS 171 172 172 LYS LYS L . n D 4 172 GLN 172 173 173 GLN GLN L . n D 4 173 SER 173 174 174 SER SER L . n D 4 174 ASN 174 175 175 ASN ASN L . n D 4 175 ASN 175 176 176 ASN ASN L . n D 4 176 LYS 176 177 177 LYS LYS L . n D 4 177 TYR 177 178 178 TYR TYR L . n D 4 178 ALA 178 179 179 ALA ALA L . n D 4 179 ALA 179 180 180 ALA ALA L . n D 4 180 SER 180 181 181 SER SER L . n D 4 181 SER 181 182 182 SER SER L . n D 4 182 TYR 182 183 183 TYR TYR L . n D 4 183 LEU 183 184 184 LEU LEU L . n D 4 184 SER 184 185 185 SER SER L . n D 4 185 LEU 185 186 186 LEU LEU L . n D 4 186 THR 186 187 187 THR THR L . n D 4 187 PRO 187 188 188 PRO PRO L . n D 4 188 GLU 188 189 189 GLU GLU L . n D 4 189 GLN 189 190 190 GLN GLN L . n D 4 190 TRP 190 191 191 TRP TRP L . n D 4 191 LYS 191 192 192 LYS LYS L . n D 4 192 SER 192 193 193 SER SER L . n D 4 193 HIS 193 194 194 HIS HIS L . n D 4 194 ARG 194 195 195 ARG ARG L . n D 4 195 SER 195 196 196 SER SER L . n D 4 196 TYR 196 197 197 TYR TYR L . n D 4 197 SER 197 198 198 SER SER L . n D 4 198 CYS 198 199 199 CYS CYS L . n D 4 199 GLN 199 200 200 GLN GLN L . n D 4 200 VAL 200 201 201 VAL VAL L . n D 4 201 THR 201 202 202 THR THR L . n D 4 202 HIS 202 203 203 HIS HIS L . n D 4 203 GLU 203 204 204 GLU GLU L . n D 4 204 GLY 204 205 205 GLY GLY L . n D 4 205 SER 205 206 206 SER SER L . n D 4 206 THR 206 207 207 THR THR L . n D 4 207 VAL 207 208 208 VAL VAL L . n D 4 208 GLU 208 209 209 GLU GLU L . n D 4 209 LYS 209 210 210 LYS LYS L . n D 4 210 THR 210 211 211 THR THR L . n D 4 211 MET 211 212 212 MET MET L . n D 4 212 ALA 212 213 213 ALA ALA L . n D 4 213 HIS 213 214 214 HIS HIS L . n D 4 214 ALA 214 215 215 ALA ALA L . n D 4 215 GLU 215 216 ? ? ? L . n D 4 216 CYS 216 217 ? ? ? L . n D 4 217 SER 217 218 ? ? ? L . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code E 5 NAG 1 1000 1000 NAG NAG G . F 5 NAG 1 1500 1500 NAG NAG G . G 5 NAG 1 2000 2000 NAG NAG G . H 5 NAG 1 2500 2500 NAG NAG G . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 B ASN 130 G ASN 272 ? ASN 'GLYCOSYLATION SITE' 2 B ASN 210 G ASN 380 ? ASN 'GLYCOSYLATION SITE' 3 B ASN 271 G ASN 441 ? ASN 'GLYCOSYLATION SITE' 4 B ASN 116 G ASN 258 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details tetrameric _pdbx_struct_assembly.oligomeric_count 4 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2010-04-07 2 'Structure model' 1 1 2011-07-13 3 'Structure model' 1 2 2017-08-23 4 'Structure model' 1 3 2017-11-01 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Source and taxonomy' 3 4 'Structure model' 'Refinement description' # loop_ _pdbx_audit_revision_category.ordinal _pdbx_audit_revision_category.revision_ordinal _pdbx_audit_revision_category.data_content_type _pdbx_audit_revision_category.category 1 3 'Structure model' entity_src_gen 2 4 'Structure model' software # _pdbx_audit_revision_item.ordinal 1 _pdbx_audit_revision_item.revision_ordinal 4 _pdbx_audit_revision_item.data_content_type 'Structure model' _pdbx_audit_revision_item.item '_software.name' # loop_ _software.pdbx_ordinal _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id 1 CNS . ? package 'Axel T. Brunger' axel.brunger@yale.edu refinement http://cns-online.org/ Fortran_77 ? 2 PDB_EXTRACT 3.005 'June 11, 2008' package PDB help@deposit.rcsb.org 'data extraction' http://sw-tools.pdb.org/apps/PDB_EXTRACT/ C++ ? 3 Blu-Ice . ? ? ? ? 'data collection' ? ? ? 4 MOSFLM . ? ? ? ? 'data reduction' ? ? ? 5 SCALA . ? ? ? ? 'data scaling' ? ? ? 6 PHASER . ? ? ? ? phasing ? ? ? # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 C H GLU 160 ? ? CD H PRO 161 ? ? 1.78 2 1 O C LEU 51 ? ? O C ASP 53 ? ? 2.05 3 1 O H ASN 104 ? ? OG1 H THR 107 ? ? 2.07 # loop_ _pdbx_validate_rmsd_bond.id _pdbx_validate_rmsd_bond.PDB_model_num _pdbx_validate_rmsd_bond.auth_atom_id_1 _pdbx_validate_rmsd_bond.auth_asym_id_1 _pdbx_validate_rmsd_bond.auth_comp_id_1 _pdbx_validate_rmsd_bond.auth_seq_id_1 _pdbx_validate_rmsd_bond.PDB_ins_code_1 _pdbx_validate_rmsd_bond.label_alt_id_1 _pdbx_validate_rmsd_bond.auth_atom_id_2 _pdbx_validate_rmsd_bond.auth_asym_id_2 _pdbx_validate_rmsd_bond.auth_comp_id_2 _pdbx_validate_rmsd_bond.auth_seq_id_2 _pdbx_validate_rmsd_bond.PDB_ins_code_2 _pdbx_validate_rmsd_bond.label_alt_id_2 _pdbx_validate_rmsd_bond.bond_value _pdbx_validate_rmsd_bond.bond_target_value _pdbx_validate_rmsd_bond.bond_deviation _pdbx_validate_rmsd_bond.bond_standard_deviation _pdbx_validate_rmsd_bond.linker_flag 1 1 CA G ASN 258 ? ? CB G ASN 258 ? ? 1.701 1.527 0.174 0.026 N 2 1 CB G ASN 258 ? ? CG G ASN 258 ? ? 1.787 1.506 0.281 0.023 N 3 1 CB G ASN 272 ? ? CG G ASN 272 ? ? 1.690 1.506 0.184 0.023 N 4 1 CB G ASN 441 ? ? CG G ASN 441 ? ? 1.666 1.506 0.160 0.023 N 5 1 CB H VAL 4 ? ? CG2 H VAL 4 ? ? 1.396 1.524 -0.128 0.021 N 6 1 CB H TRP 115 ? ? CG H TRP 115 ? ? 1.384 1.498 -0.114 0.018 N 7 1 CB L TRP 37 ? ? CG L TRP 37 ? ? 1.368 1.498 -0.130 0.018 N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 N C LYS 35 ? ? CA C LYS 35 ? ? CB C LYS 35 ? ? 99.17 110.60 -11.43 1.80 N 2 1 CA C ARG 59 ? ? CB C ARG 59 ? ? CG C ARG 59 ? ? 100.03 113.40 -13.37 2.20 N 3 1 N C GLN 110 ? ? CA C GLN 110 ? ? C C GLN 110 ? ? 128.22 111.00 17.22 2.70 N 4 1 N C VAL 146 ? ? CA C VAL 146 ? ? C C VAL 146 ? ? 94.45 111.00 -16.55 2.70 N 5 1 N C ILE 174 ? ? CA C ILE 174 ? ? C C ILE 174 ? ? 130.01 111.00 19.01 2.70 N 6 1 N G SER 114 ? ? CA G SER 114 ? ? C G SER 114 ? ? 129.72 111.00 18.72 2.70 N 7 1 CA G CYS 201 ? ? CB G CYS 201 ? ? SG G CYS 201 ? ? 125.27 114.20 11.07 1.10 N 8 1 C G ASP 207 ? ? N G PRO 208 ? ? CA G PRO 208 ? ? 136.65 119.30 17.35 1.50 Y 9 1 C G ASP 207 ? ? N G PRO 208 ? ? CD G PRO 208 ? ? 105.99 128.40 -22.41 2.10 Y 10 1 N G TYR 213 ? ? CA G TYR 213 ? ? C G TYR 213 ? ? 93.60 111.00 -17.40 2.70 N 11 1 N G VAL 251 ? ? CA G VAL 251 ? ? C G VAL 251 ? ? 89.31 111.00 -21.69 2.70 N 12 1 N G GLU 263 ? ? CA G GLU 263 ? ? C G GLU 263 ? ? 127.25 111.00 16.25 2.70 N 13 1 CA G ASN 275 ? ? C G ASN 275 ? ? N G ASN 276 ? ? 102.97 117.20 -14.23 2.20 Y 14 1 N G ASN 276 ? ? CA G ASN 276 ? ? CB G ASN 276 ? ? 92.27 110.60 -18.33 1.80 N 15 1 N G VAL 277 ? ? CA G VAL 277 ? ? C G VAL 277 ? ? 128.53 111.00 17.53 2.70 N 16 1 N G LYS 278 ? ? CA G LYS 278 ? ? C G LYS 278 ? ? 128.12 111.00 17.12 2.70 N 17 1 N G LEU 284 ? ? CA G LEU 284 ? ? C G LEU 284 ? ? 127.30 111.00 16.30 2.70 N 18 1 CA G CYS 292 ? ? CB G CYS 292 ? ? SG G CYS 292 ? ? 123.13 114.20 8.93 1.10 N 19 1 N G LYS 343 ? ? CA G LYS 343 ? ? C G LYS 343 ? ? 128.53 111.00 17.53 2.70 N 20 1 N G ASN 380 ? ? CA G ASN 380 ? ? C G ASN 380 ? ? 89.44 111.00 -21.56 2.70 N 21 1 N G HIS 389 ? ? CA G HIS 389 ? ? C G HIS 389 ? ? 134.38 111.00 23.38 2.70 N 22 1 N G ASN 390 ? ? CA G ASN 390 ? ? C G ASN 390 ? ? 131.60 111.00 20.60 2.70 N 23 1 CA G CYS 417 ? ? CB G CYS 417 ? ? SG G CYS 417 ? ? 121.21 114.20 7.01 1.10 N 24 1 C G PRO 436 ? ? N G PRO 437 ? ? CA G PRO 437 ? ? 132.00 119.30 12.70 1.50 Y 25 1 C G PRO 436 ? ? N G PRO 437 ? ? CD G PRO 437 ? ? 115.66 128.40 -12.74 2.10 Y 26 1 N G PRO 437 ? ? CA G PRO 437 ? ? C G PRO 437 ? ? 128.17 112.10 16.07 2.60 N 27 1 CB G ASN 441 ? ? CA G ASN 441 ? ? C G ASN 441 ? ? 122.67 110.40 12.27 2.00 N 28 1 N G THR 467 ? ? CA G THR 467 ? ? C G THR 467 ? ? 133.92 111.00 22.92 2.70 N 29 1 C G ARG 471 ? ? N G PRO 472 ? ? CA G PRO 472 ? ? 109.78 119.30 -9.52 1.50 Y 30 1 N G ASP 476 ? ? CA G ASP 476 ? ? C G ASP 476 ? ? 92.71 111.00 -18.29 2.70 N 31 1 CA H LEU 29 ? ? CB H LEU 29 ? ? CG H LEU 29 ? ? 134.14 115.30 18.84 2.30 N 32 1 CB H LEU 29 ? ? CG H LEU 29 ? ? CD1 H LEU 29 ? ? 99.33 111.00 -11.67 1.70 N 33 1 C H ALA 40 ? ? N H PRO 41 ? ? CA H PRO 41 ? ? 107.98 119.30 -11.32 1.50 Y 34 1 N H ILE 58 ? ? CA H ILE 58 ? ? C H ILE 58 ? ? 70.53 111.00 -40.47 2.70 N 35 1 CB H GLN 65 ? ? CA H GLN 65 ? ? C H GLN 65 ? ? 97.92 110.40 -12.48 2.00 N 36 1 CA H GLN 65 ? ? CB H GLN 65 ? ? CG H GLN 65 ? ? 127.29 113.40 13.89 2.20 N 37 1 N H ARG 67 ? ? CA H ARG 67 ? ? C H ARG 67 ? ? 130.59 111.00 19.59 2.70 N 38 1 N H SER 75 ? ? CA H SER 75 ? ? C H SER 75 ? ? 128.55 111.00 17.55 2.70 N 39 1 CB H LEU 105 ? ? CA H LEU 105 ? ? C H LEU 105 ? ? 93.17 110.20 -17.03 1.90 N 40 1 CA H LEU 105 ? ? CB H LEU 105 ? ? CG H LEU 105 ? ? 136.64 115.30 21.34 2.30 N 41 1 CB H LEU 105 ? ? CG H LEU 105 ? ? CD1 H LEU 105 ? ? 124.08 111.00 13.08 1.70 N 42 1 CB H LEU 105 ? ? CG H LEU 105 ? ? CD2 H LEU 105 ? ? 98.23 111.00 -12.77 1.70 N 43 1 N H TYR 109 ? ? CA H TYR 109 ? ? C H TYR 109 ? ? 128.58 111.00 17.58 2.70 N 44 1 C H PHE 158 ? ? N H PRO 159 ? ? CA H PRO 159 ? ? 131.23 119.30 11.93 1.50 Y 45 1 C H PHE 158 ? ? N H PRO 159 ? ? CD H PRO 159 ? ? 88.63 128.40 -39.77 2.10 Y 46 1 CA H PRO 159 ? ? N H PRO 159 ? ? CD H PRO 159 ? ? 102.38 111.70 -9.32 1.40 N 47 1 C H GLU 160 ? ? N H PRO 161 ? ? CA H PRO 161 ? ? 155.80 119.30 36.50 1.50 Y 48 1 C H GLU 160 ? ? N H PRO 161 ? ? CD H PRO 161 ? ? 77.58 128.40 -50.82 2.10 Y 49 1 C H LYS 213 ? ? N H PRO 214 ? ? CA H PRO 214 ? ? 129.19 119.30 9.89 1.50 Y 50 1 C L GLN 7 ? ? N L PRO 8 ? ? CA L PRO 8 ? ? 104.73 119.30 -14.57 1.50 Y 51 1 N L GLN 17 ? ? CA L GLN 17 ? ? C L GLN 17 ? ? 128.35 111.00 17.35 2.70 N 52 1 CA L CYS 23 ? ? CB L CYS 23 ? ? SG L CYS 23 ? ? 124.27 114.20 10.07 1.10 N 53 1 C L ILE 60 ? ? N L PRO 61 ? ? CA L PRO 61 ? ? 108.18 119.30 -11.12 1.50 Y 54 1 NE L ARG 63 ? ? CZ L ARG 63 ? ? NH1 L ARG 63 ? ? 115.78 120.30 -4.52 0.50 N 55 1 CB L LEU 75 ? ? CG L LEU 75 ? ? CD1 L LEU 75 ? ? 98.66 111.00 -12.34 1.70 N 56 1 CA L LEU 97 ? ? CB L LEU 97 ? ? CG L LEU 97 ? ? 135.59 115.30 20.29 2.30 N 57 1 CB L SER 98 ? ? CA L SER 98 ? ? C L SER 98 ? ? 96.49 110.10 -13.61 1.90 N 58 1 N L THR 99 ? ? CA L THR 99 ? ? C L THR 99 ? ? 128.39 111.00 17.39 2.70 N 59 1 C L PHE 124 ? ? N L PRO 125 ? ? CA L PRO 125 ? ? 140.06 119.30 20.76 1.50 Y 60 1 C L PHE 124 ? ? N L PRO 125 ? ? CD L PRO 125 ? ? 114.05 128.40 -14.35 2.10 Y 61 1 N L ILE 142 ? ? CA L ILE 142 ? ? C L ILE 142 ? ? 94.30 111.00 -16.70 2.70 N 62 1 N L SER 193 ? ? CA L SER 193 ? ? C L SER 193 ? ? 127.68 111.00 16.68 2.70 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 PRO C 48 ? ? -67.11 27.86 2 1 ASN C 52 ? ? -14.58 -54.99 3 1 GLU C 87 ? ? 39.96 50.02 4 1 PRO C 122 ? ? -38.81 129.59 5 1 PRO G 208 ? ? 1.81 69.51 6 1 PRO G 216 ? ? -55.83 -139.62 7 1 GLN G 254 ? ? 39.98 -14.10 8 1 ASN G 386 ? ? -140.06 18.64 9 1 ASN G 460 ? ? 120.02 -128.18 10 1 THR G 462 ? ? 29.91 31.27 11 1 PRO G 472 ? ? -61.17 -173.76 12 1 PRO H 53 ? ? -57.34 -0.56 13 1 THR H 107 ? ? 54.01 -38.01 14 1 PRO H 159 ? ? 44.84 107.39 15 1 PRO H 161 ? ? 169.32 106.75 16 1 ASN L 29 ? ? -92.70 -79.81 17 1 PRO L 42 ? ? -39.35 97.86 18 1 ASP L 53 ? ? 69.89 -60.74 19 1 ALA L 86 ? ? 170.02 -169.85 20 1 LEU L 97 ? ? 50.01 -160.01 21 1 THR L 99 ? ? -40.00 -19.99 22 1 PRO L 170 ? ? -33.86 147.95 23 1 PRO L 188 ? ? -59.21 -7.37 # _pdbx_validate_peptide_omega.id 1 _pdbx_validate_peptide_omega.PDB_model_num 1 _pdbx_validate_peptide_omega.auth_comp_id_1 SER _pdbx_validate_peptide_omega.auth_asym_id_1 L _pdbx_validate_peptide_omega.auth_seq_id_1 98 _pdbx_validate_peptide_omega.PDB_ins_code_1 ? _pdbx_validate_peptide_omega.label_alt_id_1 ? _pdbx_validate_peptide_omega.auth_comp_id_2 THR _pdbx_validate_peptide_omega.auth_asym_id_2 L _pdbx_validate_peptide_omega.auth_seq_id_2 99 _pdbx_validate_peptide_omega.PDB_ins_code_2 ? _pdbx_validate_peptide_omega.label_alt_id_2 ? _pdbx_validate_peptide_omega.omega -148.53 # _pdbx_validate_main_chain_plane.id 1 _pdbx_validate_main_chain_plane.PDB_model_num 1 _pdbx_validate_main_chain_plane.auth_comp_id SER _pdbx_validate_main_chain_plane.auth_asym_id L _pdbx_validate_main_chain_plane.auth_seq_id 98 _pdbx_validate_main_chain_plane.PDB_ins_code ? _pdbx_validate_main_chain_plane.label_alt_id ? _pdbx_validate_main_chain_plane.improper_torsion_angle -10.05 # loop_ _pdbx_validate_planes.id _pdbx_validate_planes.PDB_model_num _pdbx_validate_planes.auth_comp_id _pdbx_validate_planes.auth_asym_id _pdbx_validate_planes.auth_seq_id _pdbx_validate_planes.PDB_ins_code _pdbx_validate_planes.label_alt_id _pdbx_validate_planes.rmsd _pdbx_validate_planes.type 1 1 TYR H 94 ? ? 0.074 'SIDE CHAIN' 2 1 TYR H 102 ? ? 0.117 'SIDE CHAIN' 3 1 TYR H 110 ? ? 0.076 'SIDE CHAIN' 4 1 TYR H 114 ? ? 0.090 'SIDE CHAIN' 5 1 TYR L 34 ? ? 0.081 'SIDE CHAIN' # _pdbx_validate_chiral.id 1 _pdbx_validate_chiral.PDB_model_num 1 _pdbx_validate_chiral.auth_atom_id C1 _pdbx_validate_chiral.label_alt_id ? _pdbx_validate_chiral.auth_asym_id G _pdbx_validate_chiral.auth_comp_id NAG _pdbx_validate_chiral.auth_seq_id 2500 _pdbx_validate_chiral.PDB_ins_code ? _pdbx_validate_chiral.details 'WRONG HAND' _pdbx_validate_chiral.omega . # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 C LYS 1 ? A LYS 1 2 1 Y 1 C LEU 177 ? A LEU 177 3 1 Y 1 C ALA 178 ? A ALA 178 4 1 Y 1 C PHE 179 ? A PHE 179 5 1 Y 1 C GLN 180 ? A GLN 180 6 1 Y 1 C LYS 181 ? A LYS 181 7 1 Y 1 C ALA 182 ? A ALA 182 8 1 Y 1 C ILE 183 ? A ILE 183 9 1 Y 1 C ASP 184 ? A ASP 184 10 1 Y 1 C GLY 185 ? A GLY 185 11 1 Y 1 C ARG 186 ? A ARG 186 12 1 Y 1 C HIS 187 ? A HIS 187 13 1 Y 1 C HIS 188 ? A HIS 188 14 1 Y 1 C HIS 189 ? A HIS 189 15 1 Y 1 C HIS 190 ? A HIS 190 16 1 Y 1 C HIS 191 ? A HIS 191 17 1 Y 1 C HIS 192 ? A HIS 192 18 1 Y 1 G GLU 82 ? B GLU 1 19 1 Y 1 G ILE 83 ? B ILE 2 20 1 Y 1 G VAL 84 ? B VAL 3 21 1 Y 1 G LEU 185 ? B LEU 43 22 1 Y 1 G CYS 186 ? B CYS 44 23 1 Y 1 G VAL 187 ? B VAL 45 24 1 Y 1 G GLY 188 ? B GLY 46 25 1 Y 1 G ALA 189 ? B ALA 47 26 1 Y 1 G GLY 190 ? B GLY 48 27 1 Y 1 G ASN 191 ? B ASN 49 28 1 Y 1 G CYS 192 ? B CYS 50 29 1 Y 1 G ALA 323 ? B ALA 153 30 1 Y 1 G THR 392 ? B THR 222 31 1 Y 1 G ASP 393 ? B ASP 223 32 1 Y 1 G SER 394 ? B SER 224 33 1 Y 1 G THR 395 ? B THR 225 34 1 Y 1 G VAL 396 ? B VAL 226 35 1 Y 1 G ASN 397 ? B ASN 227 36 1 Y 1 G SER 398 ? B SER 228 37 1 Y 1 G THR 399 ? B THR 229 38 1 Y 1 G ASP 400 ? B ASP 230 39 1 Y 1 G SER 401 ? B SER 231 40 1 Y 1 G THR 402 ? B THR 232 41 1 Y 1 G ALA 403 ? B ALA 233 42 1 Y 1 G GLU 404 ? B GLU 234 43 1 Y 1 G THR 405 ? B THR 235 44 1 Y 1 G GLY 406 ? B GLY 236 45 1 Y 1 G ASN 407 ? B ASN 237 46 1 Y 1 G SER 408 ? B SER 238 47 1 Y 1 G THR 409 ? B THR 239 48 1 Y 1 G ASN 410 ? B ASN 240 49 1 Y 1 G THR 411 ? B THR 241 50 1 Y 1 G ASN 412 ? B ASN 242 51 1 Y 1 G LYS 494 ? B LYS 324 52 1 Y 1 G SER 495 ? B SER 325 53 1 Y 1 G GLY 496 ? B GLY 326 54 1 Y 1 G HIS 497 ? B HIS 327 55 1 Y 1 G HIS 498 ? B HIS 328 56 1 Y 1 G HIS 499 ? B HIS 329 57 1 Y 1 G HIS 500 ? B HIS 330 58 1 Y 1 G HIS 501 ? B HIS 331 59 1 Y 1 G HIS 502 ? B HIS 332 60 1 Y 1 H LYS 226 ? C LYS 226 61 1 Y 1 H SER 227 ? C SER 227 62 1 Y 1 H CYS 228 ? C CYS 228 63 1 Y 1 H ASP 229 ? C ASP 229 64 1 Y 1 H LYS 230 ? C LYS 230 65 1 Y 1 H THR 231 ? C THR 231 66 1 Y 1 L GLN 2 ? D GLN 1 67 1 Y 1 L GLU 216 ? D GLU 215 68 1 Y 1 L CYS 217 ? D CYS 216 69 1 Y 1 L SER 218 ? D SER 217 # _pdbx_entity_nonpoly.entity_id 5 _pdbx_entity_nonpoly.name N-ACETYL-D-GLUCOSAMINE _pdbx_entity_nonpoly.comp_id NAG #