data_3LGD # _entry.id 3LGD # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3LGD RCSB RCSB057244 WWPDB D_1000057244 # _pdbx_database_related.db_name PDB _pdbx_database_related.db_id 3LGG _pdbx_database_related.details . _pdbx_database_related.content_type unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 3LGD _pdbx_database_status.recvd_initial_deposition_date 2010-01-20 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # _audit_author.name 'Zavialov, A.V.' _audit_author.pdbx_ordinal 1 # _citation.id primary _citation.title 'Structural basis for the growth factor activity of human adenosine deaminase ADA2.' _citation.journal_abbrev J.Biol.Chem. _citation.journal_volume 285 _citation.page_first 12367 _citation.page_last 12377 _citation.year 2010 _citation.journal_id_ASTM JBCHA3 _citation.country US _citation.journal_id_ISSN 0021-9258 _citation.journal_id_CSD 0071 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 20147294 _citation.pdbx_database_id_DOI 10.1074/jbc.M109.083527 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Zavialov, A.V.' 1 primary 'Yu, X.' 2 primary 'Spillmann, D.' 3 primary 'Lauvau, G.' 4 primary 'Zavialov, A.V.' 5 # _cell.entry_id 3LGD _cell.length_a 63.212 _cell.length_b 73.099 _cell.length_c 80.662 _cell.angle_alpha 113.38 _cell.angle_beta 94.18 _cell.angle_gamma 92.16 _cell.Z_PDB 2 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 3LGD _symmetry.space_group_name_H-M 'P 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 1 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Adenosine deaminase CECR1' 59049.293 2 3.5.4.4 ? ? ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 6 ? ? ? ? 3 non-polymer syn 'ZINC ION' 65.409 2 ? ? ? ? 4 non-polymer syn 1,2-ETHANEDIOL 62.068 2 ? ? ? ? 5 non-polymer syn 'UNKNOWN ATOM OR ION' ? 2 ? ? ? ? 6 water nat water 18.015 789 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Cat eye syndrome critical region protein 1' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;GGSIDETRAHLLLKEKMMRLGGRLVLNTKEELANERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMP KGAALHLHDIGIVTMDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNF TLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSV KTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAK DGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPV ATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIA DVATKGSLHHILDAQKMVWNHRHHHHHH ; _entity_poly.pdbx_seq_one_letter_code_can ;GGSIDETRAHLLLKEKMMRLGGRLVLNTKEELANERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMP KGAALHLHDIGIVTMDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNF TLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSV KTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAK DGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPV ATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIA DVATKGSLHHILDAQKMVWNHRHHHHHH ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLY n 1 2 GLY n 1 3 SER n 1 4 ILE n 1 5 ASP n 1 6 GLU n 1 7 THR n 1 8 ARG n 1 9 ALA n 1 10 HIS n 1 11 LEU n 1 12 LEU n 1 13 LEU n 1 14 LYS n 1 15 GLU n 1 16 LYS n 1 17 MET n 1 18 MET n 1 19 ARG n 1 20 LEU n 1 21 GLY n 1 22 GLY n 1 23 ARG n 1 24 LEU n 1 25 VAL n 1 26 LEU n 1 27 ASN n 1 28 THR n 1 29 LYS n 1 30 GLU n 1 31 GLU n 1 32 LEU n 1 33 ALA n 1 34 ASN n 1 35 GLU n 1 36 ARG n 1 37 LEU n 1 38 MET n 1 39 THR n 1 40 LEU n 1 41 LYS n 1 42 ILE n 1 43 ALA n 1 44 GLU n 1 45 MET n 1 46 LYS n 1 47 GLU n 1 48 ALA n 1 49 MET n 1 50 ARG n 1 51 THR n 1 52 LEU n 1 53 ILE n 1 54 PHE n 1 55 PRO n 1 56 PRO n 1 57 SER n 1 58 MET n 1 59 HIS n 1 60 PHE n 1 61 PHE n 1 62 GLN n 1 63 ALA n 1 64 LYS n 1 65 HIS n 1 66 LEU n 1 67 ILE n 1 68 GLU n 1 69 ARG n 1 70 SER n 1 71 GLN n 1 72 VAL n 1 73 PHE n 1 74 ASN n 1 75 ILE n 1 76 LEU n 1 77 ARG n 1 78 MET n 1 79 MET n 1 80 PRO n 1 81 LYS n 1 82 GLY n 1 83 ALA n 1 84 ALA n 1 85 LEU n 1 86 HIS n 1 87 LEU n 1 88 HIS n 1 89 ASP n 1 90 ILE n 1 91 GLY n 1 92 ILE n 1 93 VAL n 1 94 THR n 1 95 MET n 1 96 ASP n 1 97 TRP n 1 98 LEU n 1 99 VAL n 1 100 ARG n 1 101 ASN n 1 102 VAL n 1 103 THR n 1 104 TYR n 1 105 ARG n 1 106 PRO n 1 107 HIS n 1 108 CYS n 1 109 HIS n 1 110 ILE n 1 111 CYS n 1 112 PHE n 1 113 THR n 1 114 PRO n 1 115 ARG n 1 116 GLY n 1 117 ILE n 1 118 MET n 1 119 GLN n 1 120 PHE n 1 121 ARG n 1 122 PHE n 1 123 ALA n 1 124 HIS n 1 125 PRO n 1 126 THR n 1 127 PRO n 1 128 ARG n 1 129 PRO n 1 130 SER n 1 131 GLU n 1 132 LYS n 1 133 CYS n 1 134 SER n 1 135 LYS n 1 136 TRP n 1 137 ILE n 1 138 LEU n 1 139 LEU n 1 140 GLU n 1 141 ASP n 1 142 TYR n 1 143 ARG n 1 144 LYS n 1 145 ARG n 1 146 VAL n 1 147 GLN n 1 148 ASN n 1 149 VAL n 1 150 THR n 1 151 GLU n 1 152 PHE n 1 153 ASP n 1 154 ASP n 1 155 SER n 1 156 LEU n 1 157 LEU n 1 158 ARG n 1 159 ASN n 1 160 PHE n 1 161 THR n 1 162 LEU n 1 163 VAL n 1 164 THR n 1 165 GLN n 1 166 HIS n 1 167 PRO n 1 168 GLU n 1 169 VAL n 1 170 ILE n 1 171 TYR n 1 172 THR n 1 173 ASN n 1 174 GLN n 1 175 ASN n 1 176 VAL n 1 177 VAL n 1 178 TRP n 1 179 SER n 1 180 LYS n 1 181 PHE n 1 182 GLU n 1 183 THR n 1 184 ILE n 1 185 PHE n 1 186 PHE n 1 187 THR n 1 188 ILE n 1 189 SER n 1 190 GLY n 1 191 LEU n 1 192 ILE n 1 193 HIS n 1 194 TYR n 1 195 ALA n 1 196 PRO n 1 197 VAL n 1 198 PHE n 1 199 ARG n 1 200 ASP n 1 201 TYR n 1 202 VAL n 1 203 PHE n 1 204 ARG n 1 205 SER n 1 206 MET n 1 207 GLN n 1 208 GLU n 1 209 PHE n 1 210 TYR n 1 211 GLU n 1 212 ASP n 1 213 ASN n 1 214 VAL n 1 215 LEU n 1 216 TYR n 1 217 MET n 1 218 GLU n 1 219 ILE n 1 220 ARG n 1 221 ALA n 1 222 ARG n 1 223 LEU n 1 224 LEU n 1 225 PRO n 1 226 VAL n 1 227 TYR n 1 228 GLU n 1 229 LEU n 1 230 SER n 1 231 GLY n 1 232 GLU n 1 233 HIS n 1 234 HIS n 1 235 ASP n 1 236 GLU n 1 237 GLU n 1 238 TRP n 1 239 SER n 1 240 VAL n 1 241 LYS n 1 242 THR n 1 243 TYR n 1 244 GLN n 1 245 GLU n 1 246 VAL n 1 247 ALA n 1 248 GLN n 1 249 LYS n 1 250 PHE n 1 251 VAL n 1 252 GLU n 1 253 THR n 1 254 HIS n 1 255 PRO n 1 256 GLU n 1 257 PHE n 1 258 ILE n 1 259 GLY n 1 260 ILE n 1 261 LYS n 1 262 ILE n 1 263 ILE n 1 264 TYR n 1 265 SER n 1 266 ASP n 1 267 HIS n 1 268 ARG n 1 269 SER n 1 270 LYS n 1 271 ASP n 1 272 VAL n 1 273 ALA n 1 274 VAL n 1 275 ILE n 1 276 ALA n 1 277 GLU n 1 278 SER n 1 279 ILE n 1 280 ARG n 1 281 MET n 1 282 ALA n 1 283 MET n 1 284 GLY n 1 285 LEU n 1 286 ARG n 1 287 ILE n 1 288 LYS n 1 289 PHE n 1 290 PRO n 1 291 THR n 1 292 VAL n 1 293 VAL n 1 294 ALA n 1 295 GLY n 1 296 PHE n 1 297 ASP n 1 298 LEU n 1 299 VAL n 1 300 GLY n 1 301 HIS n 1 302 GLU n 1 303 ASP n 1 304 THR n 1 305 GLY n 1 306 HIS n 1 307 SER n 1 308 LEU n 1 309 HIS n 1 310 ASP n 1 311 TYR n 1 312 LYS n 1 313 GLU n 1 314 ALA n 1 315 LEU n 1 316 MET n 1 317 ILE n 1 318 PRO n 1 319 ALA n 1 320 LYS n 1 321 ASP n 1 322 GLY n 1 323 VAL n 1 324 LYS n 1 325 LEU n 1 326 PRO n 1 327 TYR n 1 328 PHE n 1 329 PHE n 1 330 HIS n 1 331 ALA n 1 332 GLY n 1 333 GLU n 1 334 THR n 1 335 ASP n 1 336 TRP n 1 337 GLN n 1 338 GLY n 1 339 THR n 1 340 SER n 1 341 ILE n 1 342 ASP n 1 343 ARG n 1 344 ASN n 1 345 ILE n 1 346 LEU n 1 347 ASP n 1 348 ALA n 1 349 LEU n 1 350 MET n 1 351 LEU n 1 352 ASN n 1 353 THR n 1 354 THR n 1 355 ARG n 1 356 ILE n 1 357 GLY n 1 358 HIS n 1 359 GLY n 1 360 PHE n 1 361 ALA n 1 362 LEU n 1 363 SER n 1 364 LYS n 1 365 HIS n 1 366 PRO n 1 367 ALA n 1 368 VAL n 1 369 ARG n 1 370 THR n 1 371 TYR n 1 372 SER n 1 373 TRP n 1 374 LYS n 1 375 LYS n 1 376 ASP n 1 377 ILE n 1 378 PRO n 1 379 ILE n 1 380 GLU n 1 381 VAL n 1 382 CYS n 1 383 PRO n 1 384 ILE n 1 385 SER n 1 386 ASN n 1 387 GLN n 1 388 VAL n 1 389 LEU n 1 390 LYS n 1 391 LEU n 1 392 VAL n 1 393 SER n 1 394 ASP n 1 395 LEU n 1 396 ARG n 1 397 ASN n 1 398 HIS n 1 399 PRO n 1 400 VAL n 1 401 ALA n 1 402 THR n 1 403 LEU n 1 404 MET n 1 405 ALA n 1 406 THR n 1 407 GLY n 1 408 HIS n 1 409 PRO n 1 410 MET n 1 411 VAL n 1 412 ILE n 1 413 SER n 1 414 SER n 1 415 ASP n 1 416 ASP n 1 417 PRO n 1 418 ALA n 1 419 MET n 1 420 PHE n 1 421 GLY n 1 422 ALA n 1 423 LYS n 1 424 GLY n 1 425 LEU n 1 426 SER n 1 427 TYR n 1 428 ASP n 1 429 PHE n 1 430 TYR n 1 431 GLU n 1 432 VAL n 1 433 PHE n 1 434 MET n 1 435 GLY n 1 436 ILE n 1 437 GLY n 1 438 GLY n 1 439 MET n 1 440 LYS n 1 441 ALA n 1 442 ASP n 1 443 LEU n 1 444 ARG n 1 445 THR n 1 446 LEU n 1 447 LYS n 1 448 GLN n 1 449 LEU n 1 450 ALA n 1 451 MET n 1 452 ASN n 1 453 SER n 1 454 ILE n 1 455 LYS n 1 456 TYR n 1 457 SER n 1 458 THR n 1 459 LEU n 1 460 LEU n 1 461 GLU n 1 462 SER n 1 463 GLU n 1 464 LYS n 1 465 ASN n 1 466 THR n 1 467 PHE n 1 468 MET n 1 469 GLU n 1 470 ILE n 1 471 TRP n 1 472 LYS n 1 473 LYS n 1 474 ARG n 1 475 TRP n 1 476 ASP n 1 477 LYS n 1 478 PHE n 1 479 ILE n 1 480 ALA n 1 481 ASP n 1 482 VAL n 1 483 ALA n 1 484 THR n 1 485 LYS n 1 486 GLY n 1 487 SER n 1 488 LEU n 1 489 HIS n 1 490 HIS n 1 491 ILE n 1 492 LEU n 1 493 ASP n 1 494 ALA n 1 495 GLN n 1 496 LYS n 1 497 MET n 1 498 VAL n 1 499 TRP n 1 500 ASN n 1 501 HIS n 1 502 ARG n 1 503 HIS n 1 504 HIS n 1 505 HIS n 1 506 HIS n 1 507 HIS n 1 508 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'ADA2, CECR1, CECR1/ADA2, IDGFL' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name Drosophila _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7215 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type 'pRMHa3, pS2neo' _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pRMHa3-ADA2 _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code CECR1_HUMAN _struct_ref.pdbx_db_accession Q9NZK5 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;SIDETRAHLLLKEKMMRLGGRLVLNTKEELANERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKG AALHLHDIGIVTMDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNFTL VTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSVKT YQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDG VKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVAT LMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADV ATK ; _struct_ref.pdbx_align_begin 29 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 3LGD A 3 ? 485 ? Q9NZK5 29 ? 511 ? 3 485 2 1 3LGD B 3 ? 485 ? Q9NZK5 29 ? 511 ? 3 485 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3LGD GLY A 1 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 1 1 1 3LGD GLY A 2 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 2 2 1 3LGD GLY A 486 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 486 3 1 3LGD SER A 487 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 487 4 1 3LGD LEU A 488 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 488 5 1 3LGD HIS A 489 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 489 6 1 3LGD HIS A 490 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 490 7 1 3LGD ILE A 491 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 491 8 1 3LGD LEU A 492 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 492 9 1 3LGD ASP A 493 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 493 10 1 3LGD ALA A 494 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 494 11 1 3LGD GLN A 495 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 495 12 1 3LGD LYS A 496 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 496 13 1 3LGD MET A 497 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 497 14 1 3LGD VAL A 498 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 498 15 1 3LGD TRP A 499 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 499 16 1 3LGD ASN A 500 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 500 17 1 3LGD HIS A 501 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 501 18 1 3LGD ARG A 502 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 502 19 1 3LGD HIS A 503 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 503 20 1 3LGD HIS A 504 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 504 21 1 3LGD HIS A 505 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 505 22 1 3LGD HIS A 506 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 506 23 1 3LGD HIS A 507 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 507 24 1 3LGD HIS A 508 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 508 25 2 3LGD GLY B 1 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 1 26 2 3LGD GLY B 2 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 2 27 2 3LGD GLY B 486 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 486 28 2 3LGD SER B 487 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 487 29 2 3LGD LEU B 488 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 488 30 2 3LGD HIS B 489 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 489 31 2 3LGD HIS B 490 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 490 32 2 3LGD ILE B 491 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 491 33 2 3LGD LEU B 492 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 492 34 2 3LGD ASP B 493 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 493 35 2 3LGD ALA B 494 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 494 36 2 3LGD GLN B 495 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 495 37 2 3LGD LYS B 496 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 496 38 2 3LGD MET B 497 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 497 39 2 3LGD VAL B 498 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 498 40 2 3LGD TRP B 499 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 499 41 2 3LGD ASN B 500 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 500 42 2 3LGD HIS B 501 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 501 43 2 3LGD ARG B 502 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 502 44 2 3LGD HIS B 503 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 503 45 2 3LGD HIS B 504 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 504 46 2 3LGD HIS B 505 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 505 47 2 3LGD HIS B 506 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 506 48 2 3LGD HIS B 507 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 507 49 2 3LGD HIS B 508 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 508 50 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 EDO non-polymer . 1,2-ETHANEDIOL 'ETHYLENE GLYCOL' 'C2 H6 O2' 62.068 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 UNX non-polymer . 'UNKNOWN ATOM OR ION' ? ? ? VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 3LGD _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.88 _exptl_crystal.density_percent_sol 57.31 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.04 _exptl_crystal_grow.pdbx_details '40% MPD, 5% PEG 8000, 0.1M cacodylate, pH 6.04, VAPOR DIFFUSION, HANGING DROP, temperature 293K' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 315r' _diffrn_detector.pdbx_collection_date 2007-06-07 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator GRAPHITE _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.90 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'ESRF BEAMLINE ID29' _diffrn_source.pdbx_synchrotron_site ESRF _diffrn_source.pdbx_synchrotron_beamline ID29 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.90 # _reflns.entry_id 3LGD _reflns.observed_criterion_sigma_I ? _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 73 _reflns.d_resolution_high 1.9 _reflns.number_obs 101215 _reflns.number_all ? _reflns.percent_possible_obs 97.400 _reflns.pdbx_Rmerge_I_obs 0.100 _reflns.pdbx_Rsym_value 0.100 _reflns.pdbx_netI_over_sigmaI 8.800 _reflns.B_iso_Wilson_estimate 22.389 _reflns.pdbx_redundancy 2.100 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 # _reflns_shell.d_res_high 1.9 _reflns_shell.d_res_low 2.0 _reflns_shell.percent_possible_all 96.9 _reflns_shell.Rmerge_I_obs 0.43 _reflns_shell.pdbx_Rsym_value 0.431 _reflns_shell.meanI_over_sigI_obs 1.9 _reflns_shell.pdbx_redundancy 2.2 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 31991 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_diffrn_id ? _reflns_shell.pdbx_ordinal 1 # _refine.entry_id 3LGD _refine.ls_number_reflns_obs 82592 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 39.68 _refine.ls_d_res_high 2.00 _refine.ls_percent_reflns_obs 97.47 _refine.ls_R_factor_obs 0.18705 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.18461 _refine.ls_R_factor_R_free 0.23397 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 4.9 _refine.ls_number_reflns_R_free 4276 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.950 _refine.correlation_coeff_Fo_to_Fc_free 0.918 _refine.B_iso_mean 27.935 _refine.aniso_B[1][1] -0.11 _refine.aniso_B[2][2] 0.06 _refine.aniso_B[3][3] -0.20 _refine.aniso_B[1][2] -0.22 _refine.aniso_B[1][3] -0.16 _refine.aniso_B[2][3] -0.27 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct SAD _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.162 _refine.pdbx_overall_ESU_R_Free 0.156 _refine.overall_SU_ML 0.105 _refine.overall_SU_B 3.735 _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 7858 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 96 _refine_hist.number_atoms_solvent 789 _refine_hist.number_atoms_total 8743 _refine_hist.d_res_high 2.00 _refine_hist.d_res_low 39.68 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.014 0.022 ? 8158 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.379 1.960 ? 11032 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 5.803 5.000 ? 962 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 31.040 23.065 ? 372 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 16.120 15.000 ? 1448 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 18.139 15.000 ? 56 'X-RAY DIFFRACTION' ? r_chiral_restr 0.104 0.200 ? 1220 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.006 0.021 ? 6094 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 0.718 1.500 ? 4814 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it 1.353 2.000 ? 7825 'X-RAY DIFFRACTION' ? r_scbond_it 2.356 3.000 ? 3344 'X-RAY DIFFRACTION' ? r_scangle_it 3.778 4.500 ? 3207 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.000 _refine_ls_shell.d_res_low 2.052 _refine_ls_shell.number_reflns_R_work 6123 _refine_ls_shell.R_factor_R_work 0.251 _refine_ls_shell.percent_reflns_obs 97.01 _refine_ls_shell.R_factor_R_free 0.302 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 308 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 3LGD _struct.title 'Crystal structure of human adenosine deaminase growth factor, adenosine deaminase type 2 (ADA2)' _struct.pdbx_descriptor 'Adenosine deaminase CECR1 (E.C.3.5.4.4)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3LGD _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'TIM barrel, dimerization and receptor binding domains, Glycoprotein, Hydrolase, Growth Factor, Secreted' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 2 ? E N N 2 ? F N N 3 ? G N N 4 ? H N N 5 ? I N N 2 ? J N N 2 ? K N N 2 ? L N N 3 ? M N N 4 ? N N N 5 ? O N N 6 ? P N N 6 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 SER A 3 ? ARG A 19 ? SER A 3 ARG A 19 1 ? 17 HELX_P HELX_P2 2 ASN A 27 ? LEU A 52 ? ASN A 27 LEU A 52 1 ? 26 HELX_P HELX_P3 3 PHE A 54 ? MET A 58 ? PHE A 54 MET A 58 5 ? 5 HELX_P HELX_P4 4 HIS A 59 ? GLU A 68 ? HIS A 59 GLU A 68 1 ? 10 HELX_P HELX_P5 5 SER A 70 ? MET A 79 ? SER A 70 MET A 79 1 ? 10 HELX_P HELX_P6 6 THR A 94 ? ASN A 101 ? THR A 94 ASN A 101 1 ? 8 HELX_P HELX_P7 7 VAL A 102 ? ARG A 105 ? VAL A 102 ARG A 105 5 ? 4 HELX_P HELX_P8 8 LEU A 139 ? ARG A 145 ? LEU A 139 ARG A 145 1 ? 7 HELX_P HELX_P9 9 ASN A 148 ? PHE A 160 ? ASN A 148 PHE A 160 1 ? 13 HELX_P HELX_P10 10 HIS A 166 ? TYR A 171 ? HIS A 166 TYR A 171 1 ? 6 HELX_P HELX_P11 11 ASN A 173 ? HIS A 193 ? ASN A 173 HIS A 193 1 ? 21 HELX_P HELX_P12 12 TYR A 194 ? ASP A 212 ? TYR A 194 ASP A 212 1 ? 19 HELX_P HELX_P13 13 ASP A 235 ? HIS A 254 ? ASP A 235 HIS A 254 1 ? 20 HELX_P HELX_P14 14 ASP A 271 ? PHE A 289 ? ASP A 271 PHE A 289 1 ? 19 HELX_P HELX_P15 15 LEU A 308 ? ASP A 310 ? LEU A 308 ASP A 310 5 ? 3 HELX_P HELX_P16 16 TYR A 311 ? MET A 316 ? TYR A 311 MET A 316 1 ? 6 HELX_P HELX_P17 17 MET A 316 ? ASP A 321 ? MET A 316 ASP A 321 1 ? 6 HELX_P HELX_P18 18 ARG A 343 ? LEU A 351 ? ARG A 343 LEU A 351 1 ? 9 HELX_P HELX_P19 19 ALA A 361 ? LYS A 364 ? ALA A 361 LYS A 364 5 ? 4 HELX_P HELX_P20 20 HIS A 365 ? LYS A 375 ? HIS A 365 LYS A 375 1 ? 11 HELX_P HELX_P21 21 CYS A 382 ? LEU A 389 ? CYS A 382 LEU A 389 1 ? 8 HELX_P HELX_P22 22 ASP A 394 ? HIS A 398 ? ASP A 394 HIS A 398 5 ? 5 HELX_P HELX_P23 23 PRO A 399 ? THR A 406 ? PRO A 399 THR A 406 1 ? 8 HELX_P HELX_P24 24 ASP A 416 ? GLY A 421 ? ASP A 416 GLY A 421 5 ? 6 HELX_P HELX_P25 25 LEU A 425 ? GLY A 435 ? LEU A 425 GLY A 435 1 ? 11 HELX_P HELX_P26 26 ASP A 442 ? TYR A 456 ? ASP A 442 TYR A 456 1 ? 15 HELX_P HELX_P27 27 LEU A 460 ? THR A 484 ? LEU A 460 THR A 484 1 ? 25 HELX_P HELX_P28 28 SER B 3 ? ARG B 19 ? SER B 3 ARG B 19 1 ? 17 HELX_P HELX_P29 29 ASN B 27 ? LEU B 52 ? ASN B 27 LEU B 52 1 ? 26 HELX_P HELX_P30 30 PHE B 54 ? MET B 58 ? PHE B 54 MET B 58 5 ? 5 HELX_P HELX_P31 31 HIS B 59 ? GLU B 68 ? HIS B 59 GLU B 68 1 ? 10 HELX_P HELX_P32 32 SER B 70 ? MET B 79 ? SER B 70 MET B 79 1 ? 10 HELX_P HELX_P33 33 THR B 94 ? ASN B 101 ? THR B 94 ASN B 101 1 ? 8 HELX_P HELX_P34 34 VAL B 102 ? ARG B 105 ? VAL B 102 ARG B 105 5 ? 4 HELX_P HELX_P35 35 LEU B 139 ? ARG B 145 ? LEU B 139 ARG B 145 1 ? 7 HELX_P HELX_P36 36 ASN B 148 ? PHE B 160 ? ASN B 148 PHE B 160 1 ? 13 HELX_P HELX_P37 37 HIS B 166 ? TYR B 171 ? HIS B 166 TYR B 171 1 ? 6 HELX_P HELX_P38 38 ASN B 173 ? HIS B 193 ? ASN B 173 HIS B 193 1 ? 21 HELX_P HELX_P39 39 TYR B 194 ? ASP B 212 ? TYR B 194 ASP B 212 1 ? 19 HELX_P HELX_P40 40 ASP B 235 ? HIS B 254 ? ASP B 235 HIS B 254 1 ? 20 HELX_P HELX_P41 41 ASP B 271 ? PHE B 289 ? ASP B 271 PHE B 289 1 ? 19 HELX_P HELX_P42 42 LEU B 308 ? ASP B 310 ? LEU B 308 ASP B 310 5 ? 3 HELX_P HELX_P43 43 TYR B 311 ? MET B 316 ? TYR B 311 MET B 316 1 ? 6 HELX_P HELX_P44 44 MET B 316 ? ASP B 321 ? MET B 316 ASP B 321 1 ? 6 HELX_P HELX_P45 45 ARG B 343 ? LEU B 351 ? ARG B 343 LEU B 351 1 ? 9 HELX_P HELX_P46 46 PHE B 360 ? LYS B 364 ? PHE B 360 LYS B 364 5 ? 5 HELX_P HELX_P47 47 HIS B 365 ? LYS B 375 ? HIS B 365 LYS B 375 1 ? 11 HELX_P HELX_P48 48 CYS B 382 ? LEU B 389 ? CYS B 382 LEU B 389 1 ? 8 HELX_P HELX_P49 49 ASP B 394 ? HIS B 398 ? ASP B 394 HIS B 398 5 ? 5 HELX_P HELX_P50 50 PRO B 399 ? THR B 406 ? PRO B 399 THR B 406 1 ? 8 HELX_P HELX_P51 51 ASP B 416 ? PHE B 420 ? ASP B 416 PHE B 420 5 ? 5 HELX_P HELX_P52 52 LEU B 425 ? GLY B 435 ? LEU B 425 GLY B 435 1 ? 11 HELX_P HELX_P53 53 ASP B 442 ? TYR B 456 ? ASP B 442 TYR B 456 1 ? 15 HELX_P HELX_P54 54 LEU B 460 ? THR B 484 ? LEU B 460 THR B 484 1 ? 25 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 111 SG ? ? ? 1_555 A CYS 133 SG ? ? A CYS 111 A CYS 133 1_555 ? ? ? ? ? ? ? 2.044 ? disulf2 disulf ? ? B CYS 111 SG ? ? ? 1_555 B CYS 133 SG ? ? B CYS 111 B CYS 133 1_555 ? ? ? ? ? ? ? 2.041 ? covale1 covale ? ? B ASN 101 ND2 ? ? ? 1_555 I NAG . C1 ? ? B ASN 101 B NAG 550 1_555 ? ? ? ? ? ? ? 1.440 ? covale2 covale ? ? A ASN 101 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 101 A NAG 550 1_555 ? ? ? ? ? ? ? 1.441 ? covale3 covale ? ? A ASN 159 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 159 A NAG 650 1_555 ? ? ? ? ? ? ? 1.443 ? covale4 covale ? ? B ASN 159 ND2 ? ? ? 1_555 J NAG . C1 ? ? B ASN 159 B NAG 650 1_555 ? ? ? ? ? ? ? 1.444 ? covale5 covale ? ? A ASN 352 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 352 A NAG 750 1_555 ? ? ? ? ? ? ? 1.450 ? covale6 covale ? ? B ASN 352 ND2 ? ? ? 1_555 K NAG . C1 ? ? B ASN 352 B NAG 750 1_555 ? ? ? ? ? ? ? 1.451 ? metalc1 metalc ? ? A HIS 88 NE2 ? ? ? 1_555 F ZN . ZN ? ? A HIS 88 A ZN 850 1_555 ? ? ? ? ? ? ? 2.147 ? metalc2 metalc ? ? B HIS 88 NE2 ? ? ? 1_555 L ZN . ZN ? ? B HIS 88 B ZN 850 1_555 ? ? ? ? ? ? ? 2.191 ? metalc3 metalc ? ? B HIS 330 NE2 ? ? ? 1_555 L ZN . ZN ? ? B HIS 330 B ZN 850 1_555 ? ? ? ? ? ? ? 2.206 ? metalc4 metalc ? ? A HIS 86 NE2 ? ? ? 1_555 F ZN . ZN ? ? A HIS 86 A ZN 850 1_555 ? ? ? ? ? ? ? 2.208 ? metalc5 metalc ? ? B HIS 86 NE2 ? ? ? 1_555 L ZN . ZN ? ? B HIS 86 B ZN 850 1_555 ? ? ? ? ? ? ? 2.244 ? metalc6 metalc ? ? A HIS 330 NE2 ? ? ? 1_555 F ZN . ZN ? ? A HIS 330 A ZN 850 1_555 ? ? ? ? ? ? ? 2.257 ? metalc7 metalc ? ? B ASP 415 OD1 ? ? ? 1_555 L ZN . ZN ? ? B ASP 415 B ZN 850 1_555 ? ? ? ? ? ? ? 2.319 ? metalc8 metalc ? ? A ASP 415 OD1 ? ? ? 1_555 F ZN . ZN ? ? A ASP 415 A ZN 850 1_555 ? ? ? ? ? ? ? 2.559 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 HIS 124 A . ? HIS 124 A PRO 125 A ? PRO 125 A 1 -3.89 2 HIS 124 B . ? HIS 124 B PRO 125 B ? PRO 125 B 1 1.54 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 4 ? B ? 3 ? C ? 4 ? D ? 4 ? E ? 3 ? F ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel C 1 2 ? parallel C 2 3 ? parallel C 3 4 ? parallel D 1 2 ? parallel D 2 3 ? parallel D 3 4 ? parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel F 1 2 ? parallel F 2 3 ? parallel F 3 4 ? parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 GLY A 82 ? HIS A 88 ? GLY A 82 HIS A 88 A 2 VAL A 214 ? ALA A 221 ? VAL A 214 ALA A 221 A 3 GLY A 259 ? HIS A 267 ? GLY A 259 HIS A 267 A 4 VAL A 293 ? VAL A 299 ? VAL A 293 VAL A 299 B 1 MET A 118 ? PHE A 122 ? MET A 118 PHE A 122 B 2 CYS A 108 ? PHE A 112 ? CYS A 108 PHE A 112 B 3 ILE A 137 ? LEU A 138 ? ILE A 137 LEU A 138 C 1 HIS A 330 ? ALA A 331 ? HIS A 330 ALA A 331 C 2 ILE A 356 ? HIS A 358 ? ILE A 356 HIS A 358 C 3 ILE A 379 ? VAL A 381 ? ILE A 379 VAL A 381 C 4 MET A 410 ? ILE A 412 ? MET A 410 ILE A 412 D 1 GLY B 82 ? HIS B 88 ? GLY B 82 HIS B 88 D 2 VAL B 214 ? ALA B 221 ? VAL B 214 ALA B 221 D 3 GLY B 259 ? HIS B 267 ? GLY B 259 HIS B 267 D 4 VAL B 293 ? VAL B 299 ? VAL B 293 VAL B 299 E 1 MET B 118 ? PHE B 122 ? MET B 118 PHE B 122 E 2 CYS B 108 ? PHE B 112 ? CYS B 108 PHE B 112 E 3 ILE B 137 ? LEU B 138 ? ILE B 137 LEU B 138 F 1 HIS B 330 ? ALA B 331 ? HIS B 330 ALA B 331 F 2 ILE B 356 ? HIS B 358 ? ILE B 356 HIS B 358 F 3 ILE B 379 ? VAL B 381 ? ILE B 379 VAL B 381 F 4 MET B 410 ? ILE B 412 ? MET B 410 ILE B 412 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N LEU A 87 ? N LEU A 87 O ARG A 220 ? O ARG A 220 A 2 3 N ILE A 219 ? N ILE A 219 O ILE A 263 ? O ILE A 263 A 3 4 N ILE A 262 ? N ILE A 262 O ALA A 294 ? O ALA A 294 B 1 2 O GLN A 119 ? O GLN A 119 N CYS A 111 ? N CYS A 111 B 2 3 N ILE A 110 ? N ILE A 110 O ILE A 137 ? O ILE A 137 C 1 2 N ALA A 331 ? N ALA A 331 O GLY A 357 ? O GLY A 357 C 2 3 N ILE A 356 ? N ILE A 356 O GLU A 380 ? O GLU A 380 C 3 4 N VAL A 381 ? N VAL A 381 O VAL A 411 ? O VAL A 411 D 1 2 N LEU B 87 ? N LEU B 87 O ARG B 220 ? O ARG B 220 D 2 3 N ILE B 219 ? N ILE B 219 O ILE B 263 ? O ILE B 263 D 3 4 N ILE B 262 ? N ILE B 262 O ALA B 294 ? O ALA B 294 E 1 2 O ARG B 121 ? O ARG B 121 N HIS B 109 ? N HIS B 109 E 2 3 N ILE B 110 ? N ILE B 110 O ILE B 137 ? O ILE B 137 F 1 2 N ALA B 331 ? N ALA B 331 O GLY B 357 ? O GLY B 357 F 2 3 N ILE B 356 ? N ILE B 356 O GLU B 380 ? O GLU B 380 F 3 4 N VAL B 381 ? N VAL B 381 O VAL B 411 ? O VAL B 411 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG A 550' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 650' AC3 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 750' AC4 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE ZN A 850' AC5 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE EDO A 950' AC6 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE NAG B 550' AC7 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG B 650' AC8 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE NAG B 750' AC9 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE ZN B 850' BC1 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE EDO B 950' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 6 TRP A 97 ? TRP A 97 . ? 1_555 ? 2 AC1 6 ASN A 101 ? ASN A 101 . ? 1_555 ? 3 AC1 6 ARG A 105 ? ARG A 105 . ? 1_555 ? 4 AC1 6 ASP A 200 ? ASP A 200 . ? 1_555 ? 5 AC1 6 HOH O . ? HOH A 580 . ? 1_555 ? 6 AC1 6 HOH O . ? HOH A 831 . ? 1_555 ? 7 AC2 5 SER A 155 ? SER A 155 . ? 1_555 ? 8 AC2 5 ARG A 158 ? ARG A 158 . ? 1_555 ? 9 AC2 5 ASN A 159 ? ASN A 159 . ? 1_555 ? 10 AC2 5 HOH O . ? HOH A 557 . ? 1_555 ? 11 AC2 5 HOH O . ? HOH A 843 . ? 1_555 ? 12 AC3 5 ASN A 352 ? ASN A 352 . ? 1_555 ? 13 AC3 5 HOH O . ? HOH A 669 . ? 1_555 ? 14 AC3 5 HOH O . ? HOH A 784 . ? 1_555 ? 15 AC3 5 HOH O . ? HOH A 856 . ? 1_555 ? 16 AC3 5 HOH O . ? HOH A 896 . ? 1_555 ? 17 AC4 4 HIS A 86 ? HIS A 86 . ? 1_555 ? 18 AC4 4 HIS A 88 ? HIS A 88 . ? 1_555 ? 19 AC4 4 HIS A 330 ? HIS A 330 . ? 1_555 ? 20 AC4 4 ASP A 415 ? ASP A 415 . ? 1_555 ? 21 AC5 7 HIS A 107 ? HIS A 107 . ? 1_555 ? 22 AC5 7 HIS A 109 ? HIS A 109 . ? 1_555 ? 23 AC5 7 ALA A 123 ? ALA A 123 . ? 1_555 ? 24 AC5 7 HIS A 124 ? HIS A 124 . ? 1_555 ? 25 AC5 7 PRO A 125 ? PRO A 125 . ? 1_555 ? 26 AC5 7 THR A 126 ? THR A 126 . ? 1_555 ? 27 AC5 7 LEU A 138 ? LEU A 138 . ? 1_555 ? 28 AC6 8 TRP B 97 ? TRP B 97 . ? 1_555 ? 29 AC6 8 ASN B 101 ? ASN B 101 . ? 1_555 ? 30 AC6 8 ARG B 105 ? ARG B 105 . ? 1_555 ? 31 AC6 8 ASP B 200 ? ASP B 200 . ? 1_555 ? 32 AC6 8 HOH P . ? HOH B 603 . ? 1_555 ? 33 AC6 8 HOH P . ? HOH B 721 . ? 1_555 ? 34 AC6 8 HOH P . ? HOH B 724 . ? 1_555 ? 35 AC6 8 HOH P . ? HOH B 843 . ? 1_555 ? 36 AC7 6 ARG B 158 ? ARG B 158 . ? 1_555 ? 37 AC7 6 ASN B 159 ? ASN B 159 . ? 1_555 ? 38 AC7 6 THR B 161 ? THR B 161 . ? 1_555 ? 39 AC7 6 LYS B 180 ? LYS B 180 . ? 1_555 ? 40 AC7 6 HOH P . ? HOH B 560 . ? 1_555 ? 41 AC7 6 HOH P . ? HOH B 752 . ? 1_555 ? 42 AC8 9 ILE A 4 ? ILE A 4 . ? 1_555 ? 43 AC8 9 ALA B 319 ? ALA B 319 . ? 1_555 ? 44 AC8 9 LEU B 351 ? LEU B 351 . ? 1_555 ? 45 AC8 9 ASN B 352 ? ASN B 352 . ? 1_555 ? 46 AC8 9 HOH P . ? HOH B 680 . ? 1_555 ? 47 AC8 9 HOH P . ? HOH B 727 . ? 1_555 ? 48 AC8 9 HOH P . ? HOH B 834 . ? 1_555 ? 49 AC8 9 HOH P . ? HOH B 893 . ? 1_555 ? 50 AC8 9 HOH P . ? HOH B 901 . ? 1_555 ? 51 AC9 4 HIS B 86 ? HIS B 86 . ? 1_555 ? 52 AC9 4 HIS B 88 ? HIS B 88 . ? 1_555 ? 53 AC9 4 HIS B 330 ? HIS B 330 . ? 1_555 ? 54 AC9 4 ASP B 415 ? ASP B 415 . ? 1_555 ? 55 BC1 7 HIS B 107 ? HIS B 107 . ? 1_555 ? 56 BC1 7 HIS B 109 ? HIS B 109 . ? 1_555 ? 57 BC1 7 ALA B 123 ? ALA B 123 . ? 1_555 ? 58 BC1 7 HIS B 124 ? HIS B 124 . ? 1_555 ? 59 BC1 7 PRO B 125 ? PRO B 125 . ? 1_555 ? 60 BC1 7 THR B 126 ? THR B 126 . ? 1_555 ? 61 BC1 7 LEU B 138 ? LEU B 138 . ? 1_555 ? # _database_PDB_matrix.entry_id 3LGD _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 3LGD _atom_sites.fract_transf_matrix[1][1] 0.015820 _atom_sites.fract_transf_matrix[1][2] 0.000597 _atom_sites.fract_transf_matrix[1][3] 0.001523 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.013690 _atom_sites.fract_transf_matrix[2][3] 0.005990 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.013568 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S X ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . SER A 1 3 ? 25.747 -18.817 15.378 1.00 47.92 ? 3 SER A N 1 ATOM 2 C CA . SER A 1 3 ? 24.374 -19.338 15.624 1.00 48.17 ? 3 SER A CA 1 ATOM 3 C C . SER A 1 3 ? 23.278 -18.288 15.423 1.00 48.19 ? 3 SER A C 1 ATOM 4 O O . SER A 1 3 ? 22.180 -18.623 14.970 1.00 48.45 ? 3 SER A O 1 ATOM 5 C CB . SER A 1 3 ? 24.253 -19.941 17.016 1.00 48.25 ? 3 SER A CB 1 ATOM 6 O OG . SER A 1 3 ? 23.023 -20.634 17.126 1.00 48.68 ? 3 SER A OG 1 ATOM 7 N N . ILE A 1 4 ? 23.556 -17.031 15.771 1.00 47.80 ? 4 ILE A N 1 ATOM 8 C CA . ILE A 1 4 ? 22.637 -15.942 15.417 1.00 47.45 ? 4 ILE A CA 1 ATOM 9 C C . ILE A 1 4 ? 22.821 -15.685 13.929 1.00 46.77 ? 4 ILE A C 1 ATOM 10 O O . ILE A 1 4 ? 21.865 -15.416 13.203 1.00 46.90 ? 4 ILE A O 1 ATOM 11 C CB . ILE A 1 4 ? 22.897 -14.641 16.211 1.00 47.66 ? 4 ILE A CB 1 ATOM 12 C CG1 . ILE A 1 4 ? 23.111 -14.948 17.694 1.00 48.15 ? 4 ILE A CG1 1 ATOM 13 C CG2 . ILE A 1 4 ? 21.725 -13.674 16.037 1.00 48.10 ? 4 ILE A CG2 1 ATOM 14 C CD1 . ILE A 1 4 ? 23.778 -13.846 18.472 1.00 47.65 ? 4 ILE A CD1 1 ATOM 15 N N . ASP A 1 5 ? 24.076 -15.783 13.502 1.00 45.76 ? 5 ASP A N 1 ATOM 16 C CA . ASP A 1 5 ? 24.472 -15.749 12.112 1.00 45.13 ? 5 ASP A CA 1 ATOM 17 C C . ASP A 1 5 ? 23.731 -16.844 11.317 1.00 43.86 ? 5 ASP A C 1 ATOM 18 O O . ASP A 1 5 ? 23.369 -16.640 10.152 1.00 43.24 ? 5 ASP A O 1 ATOM 19 C CB . ASP A 1 5 ? 25.985 -15.953 12.065 1.00 46.24 ? 5 ASP A CB 1 ATOM 20 C CG . ASP A 1 5 ? 26.608 -15.465 10.786 1.00 48.70 ? 5 ASP A CG 1 ATOM 21 O OD1 . ASP A 1 5 ? 26.470 -16.173 9.762 1.00 52.84 ? 5 ASP A OD1 1 ATOM 22 O OD2 . ASP A 1 5 ? 27.264 -14.393 10.808 1.00 51.05 ? 5 ASP A OD2 1 ATOM 23 N N . GLU A 1 6 ? 23.492 -17.990 11.962 1.00 42.10 ? 6 GLU A N 1 ATOM 24 C CA . GLU A 1 6 ? 22.719 -19.077 11.366 1.00 40.39 ? 6 GLU A CA 1 ATOM 25 C C . GLU A 1 6 ? 21.212 -18.777 11.373 1.00 38.67 ? 6 GLU A C 1 ATOM 26 O O . GLU A 1 6 ? 20.519 -19.113 10.416 1.00 38.26 ? 6 GLU A O 1 ATOM 27 C CB . GLU A 1 6 ? 23.036 -20.435 12.030 1.00 41.15 ? 6 GLU A CB 1 ATOM 28 C CG . GLU A 1 6 ? 24.312 -21.107 11.459 1.00 43.01 ? 6 GLU A CG 1 ATOM 29 C CD . GLU A 1 6 ? 24.882 -22.257 12.308 1.00 46.91 ? 6 GLU A CD 1 ATOM 30 O OE1 . GLU A 1 6 ? 24.150 -22.876 13.123 1.00 48.12 ? 6 GLU A OE1 1 ATOM 31 O OE2 . GLU A 1 6 ? 26.090 -22.551 12.140 1.00 48.02 ? 6 GLU A OE2 1 ATOM 32 N N . THR A 1 7 ? 20.717 -18.152 12.443 1.00 36.29 ? 7 THR A N 1 ATOM 33 C CA . THR A 1 7 ? 19.311 -17.721 12.526 1.00 34.32 ? 7 THR A CA 1 ATOM 34 C C . THR A 1 7 ? 18.962 -16.757 11.372 1.00 32.64 ? 7 THR A C 1 ATOM 35 O O . THR A 1 7 ? 17.943 -16.927 10.691 1.00 31.74 ? 7 THR A O 1 ATOM 36 C CB . THR A 1 7 ? 18.999 -17.068 13.904 1.00 34.49 ? 7 THR A CB 1 ATOM 37 O OG1 . THR A 1 7 ? 19.247 -18.026 14.944 1.00 34.90 ? 7 THR A OG1 1 ATOM 38 C CG2 . THR A 1 7 ? 17.535 -16.602 13.992 1.00 33.28 ? 7 THR A CG2 1 ATOM 39 N N . ARG A 1 8 ? 19.833 -15.772 11.154 1.00 31.00 ? 8 ARG A N 1 ATOM 40 C CA . ARG A 1 8 ? 19.689 -14.815 10.061 1.00 29.71 ? 8 ARG A CA 1 ATOM 41 C C . ARG A 1 8 ? 19.703 -15.504 8.695 1.00 29.36 ? 8 ARG A C 1 ATOM 42 O O . ARG A 1 8 ? 18.927 -15.126 7.796 1.00 28.07 ? 8 ARG A O 1 ATOM 43 C CB . ARG A 1 8 ? 20.780 -13.751 10.135 1.00 29.79 ? 8 ARG A CB 1 ATOM 44 C CG . ARG A 1 8 ? 20.633 -12.592 9.169 1.00 28.57 ? 8 ARG A CG 1 ATOM 45 C CD . ARG A 1 8 ? 21.957 -11.880 9.003 1.00 28.91 ? 8 ARG A CD 1 ATOM 46 N NE . ARG A 1 8 ? 21.820 -10.534 8.447 1.00 26.64 ? 8 ARG A NE 1 ATOM 47 C CZ . ARG A 1 8 ? 21.937 -10.218 7.153 1.00 28.61 ? 8 ARG A CZ 1 ATOM 48 N NH1 . ARG A 1 8 ? 22.185 -11.149 6.238 1.00 26.60 ? 8 ARG A NH1 1 ATOM 49 N NH2 . ARG A 1 8 ? 21.787 -8.954 6.761 1.00 24.94 ? 8 ARG A NH2 1 ATOM 50 N N . ALA A 1 9 ? 20.575 -16.509 8.530 1.00 28.57 ? 9 ALA A N 1 ATOM 51 C CA . ALA A 1 9 ? 20.640 -17.240 7.256 1.00 28.24 ? 9 ALA A CA 1 ATOM 52 C C . ALA A 1 9 ? 19.348 -18.005 7.021 1.00 27.54 ? 9 ALA A C 1 ATOM 53 O O . ALA A 1 9 ? 18.838 -18.054 5.897 1.00 28.26 ? 9 ALA A O 1 ATOM 54 C CB . ALA A 1 9 ? 21.870 -18.163 7.184 1.00 28.57 ? 9 ALA A CB 1 ATOM 55 N N . HIS A 1 10 ? 18.799 -18.557 8.099 1.00 27.33 ? 10 HIS A N 1 ATOM 56 C CA . HIS A 1 10 ? 17.623 -19.387 8.035 1.00 27.50 ? 10 HIS A CA 1 ATOM 57 C C . HIS A 1 10 ? 16.364 -18.559 7.652 1.00 26.84 ? 10 HIS A C 1 ATOM 58 O O . HIS A 1 10 ? 15.578 -18.979 6.800 1.00 26.46 ? 10 HIS A O 1 ATOM 59 C CB . HIS A 1 10 ? 17.461 -20.120 9.369 1.00 27.96 ? 10 HIS A CB 1 ATOM 60 C CG . HIS A 1 10 ? 16.126 -20.770 9.554 1.00 30.15 ? 10 HIS A CG 1 ATOM 61 N ND1 . HIS A 1 10 ? 15.816 -22.005 9.026 1.00 32.34 ? 10 HIS A ND1 1 ATOM 62 C CD2 . HIS A 1 10 ? 15.018 -20.354 10.215 1.00 33.38 ? 10 HIS A CD2 1 ATOM 63 C CE1 . HIS A 1 10 ? 14.572 -22.319 9.342 1.00 32.65 ? 10 HIS A CE1 1 ATOM 64 N NE2 . HIS A 1 10 ? 14.064 -21.334 10.066 1.00 33.38 ? 10 HIS A NE2 1 ATOM 65 N N . LEU A 1 11 ? 16.193 -17.394 8.281 1.00 26.07 ? 11 LEU A N 1 ATOM 66 C CA . LEU A 1 11 ? 15.064 -16.503 7.979 1.00 25.83 ? 11 LEU A CA 1 ATOM 67 C C . LEU A 1 11 ? 15.098 -16.064 6.505 1.00 25.49 ? 11 LEU A C 1 ATOM 68 O O . LEU A 1 11 ? 14.098 -16.144 5.810 1.00 25.58 ? 11 LEU A O 1 ATOM 69 C CB . LEU A 1 11 ? 15.012 -15.315 8.966 1.00 25.27 ? 11 LEU A CB 1 ATOM 70 C CG . LEU A 1 11 ? 14.743 -15.672 10.447 1.00 25.51 ? 11 LEU A CG 1 ATOM 71 C CD1 . LEU A 1 11 ? 15.018 -14.532 11.419 1.00 26.72 ? 11 LEU A CD1 1 ATOM 72 C CD2 . LEU A 1 11 ? 13.356 -16.247 10.701 1.00 26.26 ? 11 LEU A CD2 1 ATOM 73 N N . LEU A 1 12 ? 16.265 -15.659 6.022 1.00 25.34 ? 12 LEU A N 1 ATOM 74 C CA . LEU A 1 12 ? 16.418 -15.319 4.607 1.00 25.69 ? 12 LEU A CA 1 ATOM 75 C C . LEU A 1 12 ? 16.118 -16.473 3.643 1.00 25.68 ? 12 LEU A C 1 ATOM 76 O O . LEU A 1 12 ? 15.565 -16.243 2.556 1.00 24.59 ? 12 LEU A O 1 ATOM 77 C CB . LEU A 1 12 ? 17.803 -14.724 4.324 1.00 25.56 ? 12 LEU A CB 1 ATOM 78 C CG . LEU A 1 12 ? 17.987 -13.291 4.850 1.00 26.36 ? 12 LEU A CG 1 ATOM 79 C CD1 . LEU A 1 12 ? 19.435 -12.836 4.715 1.00 26.70 ? 12 LEU A CD1 1 ATOM 80 C CD2 . LEU A 1 12 ? 16.989 -12.278 4.183 1.00 24.71 ? 12 LEU A CD2 1 ATOM 81 N N . LEU A 1 13 ? 16.493 -17.699 4.030 1.00 25.53 ? 13 LEU A N 1 ATOM 82 C CA . LEU A 1 13 ? 16.254 -18.872 3.182 1.00 25.41 ? 13 LEU A CA 1 ATOM 83 C C . LEU A 1 13 ? 14.792 -19.256 3.226 1.00 25.14 ? 13 LEU A C 1 ATOM 84 O O . LEU A 1 13 ? 14.222 -19.635 2.203 1.00 24.63 ? 13 LEU A O 1 ATOM 85 C CB . LEU A 1 13 ? 17.144 -20.067 3.563 1.00 25.72 ? 13 LEU A CB 1 ATOM 86 C CG . LEU A 1 13 ? 17.016 -21.339 2.702 1.00 27.87 ? 13 LEU A CG 1 ATOM 87 C CD1 . LEU A 1 13 ? 17.587 -21.149 1.285 1.00 29.65 ? 13 LEU A CD1 1 ATOM 88 C CD2 . LEU A 1 13 ? 17.681 -22.564 3.389 1.00 29.67 ? 13 LEU A CD2 1 ATOM 89 N N . LYS A 1 14 ? 14.182 -19.174 4.407 1.00 25.11 ? 14 LYS A N 1 ATOM 90 C CA . LYS A 1 14 ? 12.751 -19.416 4.495 1.00 25.75 ? 14 LYS A CA 1 ATOM 91 C C . LYS A 1 14 ? 11.972 -18.473 3.551 1.00 24.77 ? 14 LYS A C 1 ATOM 92 O O . LYS A 1 14 ? 11.050 -18.914 2.862 1.00 24.78 ? 14 LYS A O 1 ATOM 93 C CB . LYS A 1 14 ? 12.233 -19.299 5.933 1.00 26.05 ? 14 LYS A CB 1 ATOM 94 C CG . LYS A 1 14 ? 10.750 -19.664 6.019 1.00 29.60 ? 14 LYS A CG 1 ATOM 95 C CD . LYS A 1 14 ? 10.136 -19.422 7.394 1.00 36.50 ? 14 LYS A CD 1 ATOM 96 C CE . LYS A 1 14 ? 10.744 -20.347 8.435 1.00 38.40 ? 14 LYS A CE 1 ATOM 97 N NZ . LYS A 1 14 ? 10.938 -19.599 9.714 1.00 42.45 ? 14 LYS A NZ 1 ATOM 98 N N . GLU A 1 15 ? 12.347 -17.192 3.508 1.00 24.18 ? 15 GLU A N 1 ATOM 99 C CA . GLU A 1 15 ? 11.651 -16.236 2.634 1.00 23.48 ? 15 GLU A CA 1 ATOM 100 C C . GLU A 1 15 ? 11.905 -16.505 1.142 1.00 23.55 ? 15 GLU A C 1 ATOM 101 O O . GLU A 1 15 ? 11.004 -16.340 0.291 1.00 21.96 ? 15 GLU A O 1 ATOM 102 C CB . GLU A 1 15 ? 11.994 -14.790 3.013 1.00 22.73 ? 15 GLU A CB 1 ATOM 103 C CG . GLU A 1 15 ? 11.510 -14.466 4.415 1.00 23.29 ? 15 GLU A CG 1 ATOM 104 C CD . GLU A 1 15 ? 11.509 -13.002 4.767 1.00 25.42 ? 15 GLU A CD 1 ATOM 105 O OE1 . GLU A 1 15 ? 12.294 -12.227 4.177 1.00 26.78 ? 15 GLU A OE1 1 ATOM 106 O OE2 . GLU A 1 15 ? 10.715 -12.639 5.662 1.00 24.86 ? 15 GLU A OE2 1 ATOM 107 N N . LYS A 1 16 ? 13.128 -16.920 0.839 1.00 23.31 ? 16 LYS A N 1 ATOM 108 C CA . LYS A 1 16 ? 13.494 -17.298 -0.529 1.00 24.18 ? 16 LYS A CA 1 ATOM 109 C C . LYS A 1 16 ? 12.644 -18.445 -1.046 1.00 23.98 ? 16 LYS A C 1 ATOM 110 O O . LYS A 1 16 ? 12.196 -18.415 -2.213 1.00 24.22 ? 16 LYS A O 1 ATOM 111 C CB . LYS A 1 16 ? 14.980 -17.663 -0.633 1.00 24.42 ? 16 LYS A CB 1 ATOM 112 C CG . LYS A 1 16 ? 15.414 -18.017 -2.071 1.00 24.99 ? 16 LYS A CG 1 ATOM 113 C CD . LYS A 1 16 ? 16.861 -18.517 -2.099 1.00 28.49 ? 16 LYS A CD 1 ATOM 114 C CE . LYS A 1 16 ? 17.681 -17.786 -3.160 1.00 32.10 ? 16 LYS A CE 1 ATOM 115 N NZ . LYS A 1 16 ? 17.246 -17.988 -4.551 1.00 31.48 ? 16 LYS A NZ 1 ATOM 116 N N . MET A 1 17 ? 12.412 -19.433 -0.173 1.00 23.86 ? 17 MET A N 1 ATOM 117 C CA . MET A 1 17 ? 11.621 -20.618 -0.504 1.00 24.92 ? 17 MET A CA 1 ATOM 118 C C . MET A 1 17 ? 10.118 -20.355 -0.582 1.00 24.39 ? 17 MET A C 1 ATOM 119 O O . MET A 1 17 ? 9.435 -21.002 -1.371 1.00 24.06 ? 17 MET A O 1 ATOM 120 C CB . MET A 1 17 ? 11.863 -21.763 0.505 1.00 25.50 ? 17 MET A CB 1 ATOM 121 C CG . MET A 1 17 ? 13.291 -22.348 0.498 1.00 29.36 ? 17 MET A CG 1 ATOM 122 S SD . MET A 1 17 ? 13.760 -22.994 -1.125 1.00 35.98 ? 17 MET A SD 1 ATOM 123 C CE . MET A 1 17 ? 15.009 -21.823 -1.643 1.00 33.51 ? 17 MET A CE 1 ATOM 124 N N . MET A 1 18 ? 9.601 -19.437 0.233 1.00 23.77 ? 18 MET A N 1 ATOM 125 C CA . MET A 1 18 ? 8.141 -19.217 0.244 1.00 24.37 ? 18 MET A CA 1 ATOM 126 C C . MET A 1 18 ? 7.569 -18.217 -0.778 1.00 23.80 ? 18 MET A C 1 ATOM 127 O O . MET A 1 18 ? 6.387 -18.332 -1.158 1.00 23.70 ? 18 MET A O 1 ATOM 128 C CB . MET A 1 18 ? 7.581 -18.962 1.656 1.00 25.10 ? 18 MET A CB 1 ATOM 129 C CG . MET A 1 18 ? 8.196 -17.864 2.473 1.00 28.51 ? 18 MET A CG 1 ATOM 130 S SD . MET A 1 18 ? 7.652 -17.890 4.241 1.00 36.76 ? 18 MET A SD 1 ATOM 131 C CE . MET A 1 18 ? 7.395 -19.637 4.518 1.00 35.33 ? 18 MET A CE 1 ATOM 132 N N . ARG A 1 19 ? 8.377 -17.251 -1.221 1.00 23.35 ? 19 ARG A N 1 ATOM 133 C CA . ARG A 1 19 ? 7.935 -16.352 -2.283 1.00 23.60 ? 19 ARG A CA 1 ATOM 134 C C . ARG A 1 19 ? 7.586 -17.121 -3.558 1.00 23.74 ? 19 ARG A C 1 ATOM 135 O O . ARG A 1 19 ? 8.040 -18.252 -3.759 1.00 23.68 ? 19 ARG A O 1 ATOM 136 C CB . ARG A 1 19 ? 8.920 -15.195 -2.565 1.00 24.01 ? 19 ARG A CB 1 ATOM 137 C CG . ARG A 1 19 ? 10.168 -15.547 -3.334 1.00 24.27 ? 19 ARG A CG 1 ATOM 138 C CD . ARG A 1 19 ? 11.012 -14.281 -3.628 1.00 26.71 ? 19 ARG A CD 1 ATOM 139 N NE . ARG A 1 19 ? 11.496 -13.659 -2.404 1.00 26.26 ? 19 ARG A NE 1 ATOM 140 C CZ . ARG A 1 19 ? 12.731 -13.787 -1.926 1.00 28.13 ? 19 ARG A CZ 1 ATOM 141 N NH1 . ARG A 1 19 ? 13.636 -14.498 -2.585 1.00 29.23 ? 19 ARG A NH1 1 ATOM 142 N NH2 . ARG A 1 19 ? 13.066 -13.200 -0.793 1.00 27.25 ? 19 ARG A NH2 1 ATOM 143 N N . LEU A 1 20 ? 6.784 -16.485 -4.411 1.00 23.45 ? 20 LEU A N 1 ATOM 144 C CA . LEU A 1 20 ? 6.250 -17.114 -5.597 1.00 23.61 ? 20 LEU A CA 1 ATOM 145 C C . LEU A 1 20 ? 7.377 -17.691 -6.443 1.00 24.02 ? 20 LEU A C 1 ATOM 146 O O . LEU A 1 20 ? 8.335 -16.975 -6.777 1.00 22.59 ? 20 LEU A O 1 ATOM 147 C CB . LEU A 1 20 ? 5.443 -16.094 -6.399 1.00 24.35 ? 20 LEU A CB 1 ATOM 148 C CG . LEU A 1 20 ? 4.543 -16.636 -7.505 1.00 25.30 ? 20 LEU A CG 1 ATOM 149 C CD1 . LEU A 1 20 ? 3.157 -16.773 -6.977 1.00 26.43 ? 20 LEU A CD1 1 ATOM 150 C CD2 . LEU A 1 20 ? 4.527 -15.641 -8.621 1.00 28.35 ? 20 LEU A CD2 1 ATOM 151 N N . GLY A 1 21 ? 7.270 -18.994 -6.739 1.00 23.79 ? 21 GLY A N 1 ATOM 152 C CA . GLY A 1 21 ? 8.247 -19.689 -7.568 1.00 24.48 ? 21 GLY A CA 1 ATOM 153 C C . GLY A 1 21 ? 9.499 -20.168 -6.841 1.00 25.13 ? 21 GLY A C 1 ATOM 154 O O . GLY A 1 21 ? 10.392 -20.763 -7.462 1.00 25.00 ? 21 GLY A O 1 ATOM 155 N N . GLY A 1 22 ? 9.567 -19.908 -5.537 1.00 25.60 ? 22 GLY A N 1 ATOM 156 C CA . GLY A 1 22 ? 10.787 -20.106 -4.753 1.00 26.22 ? 22 GLY A CA 1 ATOM 157 C C . GLY A 1 22 ? 11.292 -21.539 -4.698 1.00 27.24 ? 22 GLY A C 1 ATOM 158 O O . GLY A 1 22 ? 12.504 -21.773 -4.619 1.00 27.39 ? 22 GLY A O 1 ATOM 159 N N . ARG A 1 23 ? 10.374 -22.498 -4.772 1.00 27.86 ? 23 ARG A N 1 ATOM 160 C CA . ARG A 1 23 ? 10.740 -23.913 -4.693 1.00 29.03 ? 23 ARG A CA 1 ATOM 161 C C . ARG A 1 23 ? 10.999 -24.565 -6.066 1.00 28.74 ? 23 ARG A C 1 ATOM 162 O O . ARG A 1 23 ? 11.343 -25.747 -6.125 1.00 28.67 ? 23 ARG A O 1 ATOM 163 C CB . ARG A 1 23 ? 9.693 -24.697 -3.881 1.00 29.60 ? 23 ARG A CB 1 ATOM 164 C CG . ARG A 1 23 ? 9.739 -24.375 -2.391 1.00 33.27 ? 23 ARG A CG 1 ATOM 165 C CD . ARG A 1 23 ? 8.732 -25.182 -1.615 1.00 38.50 ? 23 ARG A CD 1 ATOM 166 N NE . ARG A 1 23 ? 8.968 -25.073 -0.178 1.00 45.36 ? 23 ARG A NE 1 ATOM 167 C CZ . ARG A 1 23 ? 8.482 -25.919 0.738 1.00 49.50 ? 23 ARG A CZ 1 ATOM 168 N NH1 . ARG A 1 23 ? 7.719 -26.954 0.378 1.00 50.64 ? 23 ARG A NH1 1 ATOM 169 N NH2 . ARG A 1 23 ? 8.755 -25.735 2.028 1.00 50.32 ? 23 ARG A NH2 1 ATOM 170 N N . LEU A 1 24 ? 10.870 -23.788 -7.149 1.00 27.94 ? 24 LEU A N 1 ATOM 171 C CA . LEU A 1 24 ? 11.124 -24.284 -8.507 1.00 28.05 ? 24 LEU A CA 1 ATOM 172 C C . LEU A 1 24 ? 12.614 -24.625 -8.728 1.00 28.26 ? 24 LEU A C 1 ATOM 173 O O . LEU A 1 24 ? 13.506 -23.869 -8.310 1.00 28.95 ? 24 LEU A O 1 ATOM 174 C CB . LEU A 1 24 ? 10.646 -23.274 -9.582 1.00 27.16 ? 24 LEU A CB 1 ATOM 175 C CG . LEU A 1 24 ? 9.131 -23.022 -9.750 1.00 26.06 ? 24 LEU A CG 1 ATOM 176 C CD1 . LEU A 1 24 ? 8.788 -22.056 -10.907 1.00 22.26 ? 24 LEU A CD1 1 ATOM 177 C CD2 . LEU A 1 24 ? 8.371 -24.340 -9.910 1.00 25.62 ? 24 LEU A CD2 1 ATOM 178 N N . VAL A 1 25 ? 12.867 -25.755 -9.386 1.00 28.49 ? 25 VAL A N 1 ATOM 179 C CA . VAL A 1 25 ? 14.239 -26.173 -9.737 1.00 28.37 ? 25 VAL A CA 1 ATOM 180 C C . VAL A 1 25 ? 14.616 -25.680 -11.138 1.00 27.81 ? 25 VAL A C 1 ATOM 181 O O . VAL A 1 25 ? 13.909 -25.932 -12.091 1.00 27.83 ? 25 VAL A O 1 ATOM 182 C CB . VAL A 1 25 ? 14.425 -27.729 -9.629 1.00 29.01 ? 25 VAL A CB 1 ATOM 183 C CG1 . VAL A 1 25 ? 15.858 -28.144 -10.015 1.00 28.66 ? 25 VAL A CG1 1 ATOM 184 C CG2 . VAL A 1 25 ? 14.108 -28.215 -8.216 1.00 28.33 ? 25 VAL A CG2 1 ATOM 185 N N . LEU A 1 26 ? 15.719 -24.948 -11.236 1.00 28.21 ? 26 LEU A N 1 ATOM 186 C CA . LEU A 1 26 ? 16.249 -24.469 -12.502 1.00 28.59 ? 26 LEU A CA 1 ATOM 187 C C . LEU A 1 26 ? 17.332 -25.432 -13.012 1.00 29.63 ? 26 LEU A C 1 ATOM 188 O O . LEU A 1 26 ? 18.078 -25.996 -12.222 1.00 29.66 ? 26 LEU A O 1 ATOM 189 C CB . LEU A 1 26 ? 16.843 -23.066 -12.329 1.00 28.06 ? 26 LEU A CB 1 ATOM 190 C CG . LEU A 1 26 ? 16.054 -21.801 -12.749 1.00 29.04 ? 26 LEU A CG 1 ATOM 191 C CD1 . LEU A 1 26 ? 14.510 -21.952 -12.778 1.00 26.84 ? 26 LEU A CD1 1 ATOM 192 C CD2 . LEU A 1 26 ? 16.494 -20.584 -11.976 1.00 26.88 ? 26 LEU A CD2 1 ATOM 193 N N . ASN A 1 27 ? 17.400 -25.626 -14.325 1.00 30.11 ? 27 ASN A N 1 ATOM 194 C CA . ASN A 1 27 ? 18.523 -26.351 -14.918 1.00 30.61 ? 27 ASN A CA 1 ATOM 195 C C . ASN A 1 27 ? 19.697 -25.401 -15.150 1.00 31.05 ? 27 ASN A C 1 ATOM 196 O O . ASN A 1 27 ? 19.589 -24.195 -14.892 1.00 30.60 ? 27 ASN A O 1 ATOM 197 C CB . ASN A 1 27 ? 18.105 -27.111 -16.187 1.00 30.14 ? 27 ASN A CB 1 ATOM 198 C CG . ASN A 1 27 ? 17.701 -26.205 -17.338 1.00 30.32 ? 27 ASN A CG 1 ATOM 199 O OD1 . ASN A 1 27 ? 18.322 -25.179 -17.611 1.00 32.16 ? 27 ASN A OD1 1 ATOM 200 N ND2 . ASN A 1 27 ? 16.676 -26.623 -18.060 1.00 31.21 ? 27 ASN A ND2 1 ATOM 201 N N . THR A 1 28 ? 20.822 -25.933 -15.622 1.00 30.65 ? 28 THR A N 1 ATOM 202 C CA . THR A 1 28 ? 22.055 -25.157 -15.650 1.00 30.43 ? 28 THR A CA 1 ATOM 203 C C . THR A 1 28 ? 21.945 -23.989 -16.635 1.00 29.69 ? 28 THR A C 1 ATOM 204 O O . THR A 1 28 ? 22.426 -22.883 -16.364 1.00 29.19 ? 28 THR A O 1 ATOM 205 C CB . THR A 1 28 ? 23.306 -26.082 -15.883 1.00 31.16 ? 28 THR A CB 1 ATOM 206 O OG1 . THR A 1 28 ? 22.953 -27.142 -16.772 1.00 33.73 ? 28 THR A OG1 1 ATOM 207 C CG2 . THR A 1 28 ? 23.726 -26.742 -14.588 1.00 30.59 ? 28 THR A CG2 1 ATOM 208 N N . LYS A 1 29 ? 21.257 -24.215 -17.747 1.00 29.02 ? 29 LYS A N 1 ATOM 209 C CA . LYS A 1 29 ? 21.002 -23.150 -18.727 1.00 29.33 ? 29 LYS A CA 1 ATOM 210 C C . LYS A 1 29 ? 20.078 -22.025 -18.196 1.00 28.31 ? 29 LYS A C 1 ATOM 211 O O . LYS A 1 29 ? 20.278 -20.848 -18.517 1.00 27.94 ? 29 LYS A O 1 ATOM 212 C CB . LYS A 1 29 ? 20.446 -23.740 -20.027 1.00 29.64 ? 29 LYS A CB 1 ATOM 213 C CG . LYS A 1 29 ? 21.488 -23.809 -21.133 1.00 33.97 ? 29 LYS A CG 1 ATOM 214 C CD . LYS A 1 29 ? 21.160 -24.867 -22.205 1.00 39.22 ? 29 LYS A CD 1 ATOM 215 C CE . LYS A 1 29 ? 21.859 -24.556 -23.539 1.00 42.65 ? 29 LYS A CE 1 ATOM 216 N NZ . LYS A 1 29 ? 23.273 -24.045 -23.383 1.00 45.10 ? 29 LYS A NZ 1 ATOM 217 N N . GLU A 1 30 ? 19.074 -22.417 -17.407 1.00 27.52 ? 30 GLU A N 1 ATOM 218 C CA . GLU A 1 30 ? 18.195 -21.478 -16.692 1.00 27.45 ? 30 GLU A CA 1 ATOM 219 C C . GLU A 1 30 ? 18.942 -20.705 -15.589 1.00 27.23 ? 30 GLU A C 1 ATOM 220 O O . GLU A 1 30 ? 18.705 -19.507 -15.396 1.00 26.64 ? 30 GLU A O 1 ATOM 221 C CB . GLU A 1 30 ? 16.979 -22.211 -16.098 1.00 27.07 ? 30 GLU A CB 1 ATOM 222 C CG . GLU A 1 30 ? 15.935 -22.656 -17.137 1.00 26.08 ? 30 GLU A CG 1 ATOM 223 C CD . GLU A 1 30 ? 14.896 -23.601 -16.563 1.00 26.27 ? 30 GLU A CD 1 ATOM 224 O OE1 . GLU A 1 30 ? 15.266 -24.496 -15.772 1.00 24.75 ? 30 GLU A OE1 1 ATOM 225 O OE2 . GLU A 1 30 ? 13.688 -23.442 -16.893 1.00 28.27 ? 30 GLU A OE2 1 ATOM 226 N N . GLU A 1 31 ? 19.837 -21.383 -14.862 1.00 26.90 ? 31 GLU A N 1 ATOM 227 C CA . GLU A 1 31 ? 20.669 -20.683 -13.867 1.00 27.64 ? 31 GLU A CA 1 ATOM 228 C C . GLU A 1 31 ? 21.482 -19.569 -14.541 1.00 27.29 ? 31 GLU A C 1 ATOM 229 O O . GLU A 1 31 ? 21.548 -18.440 -14.040 1.00 27.22 ? 31 GLU A O 1 ATOM 230 C CB . GLU A 1 31 ? 21.570 -21.648 -13.082 1.00 27.92 ? 31 GLU A CB 1 ATOM 231 C CG . GLU A 1 31 ? 20.834 -22.521 -12.084 1.00 29.91 ? 31 GLU A CG 1 ATOM 232 C CD . GLU A 1 31 ? 20.395 -21.779 -10.812 1.00 35.20 ? 31 GLU A CD 1 ATOM 233 O OE1 . GLU A 1 31 ? 20.697 -20.563 -10.653 1.00 37.64 ? 31 GLU A OE1 1 ATOM 234 O OE2 . GLU A 1 31 ? 19.747 -22.421 -9.951 1.00 36.30 ? 31 GLU A OE2 1 ATOM 235 N N . LEU A 1 32 ? 22.073 -19.872 -15.694 1.00 26.72 ? 32 LEU A N 1 ATOM 236 C CA . LEU A 1 32 ? 22.777 -18.848 -16.460 1.00 26.48 ? 32 LEU A CA 1 ATOM 237 C C . LEU A 1 32 ? 21.863 -17.682 -16.921 1.00 25.20 ? 32 LEU A C 1 ATOM 238 O O . LEU A 1 32 ? 22.249 -16.507 -16.821 1.00 25.52 ? 32 LEU A O 1 ATOM 239 C CB . LEU A 1 32 ? 23.508 -19.473 -17.648 1.00 26.47 ? 32 LEU A CB 1 ATOM 240 C CG . LEU A 1 32 ? 24.793 -18.784 -18.107 1.00 28.83 ? 32 LEU A CG 1 ATOM 241 C CD1 . LEU A 1 32 ? 24.541 -17.472 -18.856 1.00 30.53 ? 32 LEU A CD1 1 ATOM 242 C CD2 . LEU A 1 32 ? 25.780 -18.558 -16.942 1.00 31.52 ? 32 LEU A CD2 1 ATOM 243 N N . ALA A 1 33 ? 20.681 -18.004 -17.448 1.00 24.54 ? 33 ALA A N 1 ATOM 244 C CA . ALA A 1 33 ? 19.709 -16.987 -17.863 1.00 22.83 ? 33 ALA A CA 1 ATOM 245 C C . ALA A 1 33 ? 19.309 -16.103 -16.669 1.00 22.33 ? 33 ALA A C 1 ATOM 246 O O . ALA A 1 33 ? 19.277 -14.887 -16.798 1.00 21.15 ? 33 ALA A O 1 ATOM 247 C CB . ALA A 1 33 ? 18.453 -17.633 -18.494 1.00 23.31 ? 33 ALA A CB 1 ATOM 248 N N . ASN A 1 34 ? 19.043 -16.731 -15.528 1.00 21.29 ? 34 ASN A N 1 ATOM 249 C CA . ASN A 1 34 ? 18.761 -16.013 -14.283 1.00 22.19 ? 34 ASN A CA 1 ATOM 250 C C . ASN A 1 34 ? 19.863 -15.045 -13.863 1.00 22.39 ? 34 ASN A C 1 ATOM 251 O O . ASN A 1 34 ? 19.596 -13.913 -13.465 1.00 22.11 ? 34 ASN A O 1 ATOM 252 C CB . ASN A 1 34 ? 18.491 -16.973 -13.122 1.00 21.66 ? 34 ASN A CB 1 ATOM 253 C CG . ASN A 1 34 ? 17.899 -16.247 -11.897 1.00 22.73 ? 34 ASN A CG 1 ATOM 254 O OD1 . ASN A 1 34 ? 16.801 -15.702 -11.960 1.00 22.42 ? 34 ASN A OD1 1 ATOM 255 N ND2 . ASN A 1 34 ? 18.641 -16.219 -10.804 1.00 19.74 ? 34 ASN A ND2 1 ATOM 256 N N . GLU A 1 35 ? 21.109 -15.503 -13.958 1.00 22.86 ? 35 GLU A N 1 ATOM 257 C CA . GLU A 1 35 ? 22.244 -14.711 -13.535 1.00 23.36 ? 35 GLU A CA 1 ATOM 258 C C . GLU A 1 35 ? 22.321 -13.450 -14.397 1.00 22.63 ? 35 GLU A C 1 ATOM 259 O O . GLU A 1 35 ? 22.552 -12.374 -13.883 1.00 23.04 ? 35 GLU A O 1 ATOM 260 C CB . GLU A 1 35 ? 23.544 -15.532 -13.647 1.00 23.90 ? 35 GLU A CB 1 ATOM 261 C CG . GLU A 1 35 ? 24.806 -14.767 -13.300 1.00 28.25 ? 35 GLU A CG 1 ATOM 262 C CD . GLU A 1 35 ? 26.048 -15.661 -13.385 1.00 34.26 ? 35 GLU A CD 1 ATOM 263 O OE1 . GLU A 1 35 ? 26.850 -15.499 -14.345 1.00 34.55 ? 35 GLU A OE1 1 ATOM 264 O OE2 . GLU A 1 35 ? 26.200 -16.540 -12.505 1.00 36.77 ? 35 GLU A OE2 1 ATOM 265 N N . ARG A 1 36 ? 22.122 -13.599 -15.703 1.00 22.18 ? 36 ARG A N 1 ATOM 266 C CA . ARG A 1 36 ? 22.158 -12.469 -16.621 1.00 22.16 ? 36 ARG A CA 1 ATOM 267 C C . ARG A 1 36 ? 20.967 -11.502 -16.434 1.00 21.45 ? 36 ARG A C 1 ATOM 268 O O . ARG A 1 36 ? 21.124 -10.274 -16.480 1.00 20.98 ? 36 ARG A O 1 ATOM 269 C CB . ARG A 1 36 ? 22.176 -12.970 -18.073 1.00 22.79 ? 36 ARG A CB 1 ATOM 270 C CG . ARG A 1 36 ? 23.276 -13.995 -18.351 1.00 27.71 ? 36 ARG A CG 1 ATOM 271 C CD . ARG A 1 36 ? 23.492 -14.195 -19.815 1.00 32.35 ? 36 ARG A CD 1 ATOM 272 N NE . ARG A 1 36 ? 24.601 -13.377 -20.268 1.00 37.89 ? 36 ARG A NE 1 ATOM 273 C CZ . ARG A 1 36 ? 24.781 -12.965 -21.521 1.00 38.61 ? 36 ARG A CZ 1 ATOM 274 N NH1 . ARG A 1 36 ? 23.914 -13.294 -22.478 1.00 38.96 ? 36 ARG A NH1 1 ATOM 275 N NH2 . ARG A 1 36 ? 25.834 -12.213 -21.809 1.00 40.05 ? 36 ARG A NH2 1 ATOM 276 N N . LEU A 1 37 ? 19.770 -12.052 -16.291 1.00 21.07 ? 37 LEU A N 1 ATOM 277 C CA . LEU A 1 37 ? 18.571 -11.199 -16.153 1.00 20.50 ? 37 LEU A CA 1 ATOM 278 C C . LEU A 1 37 ? 18.659 -10.424 -14.823 1.00 19.61 ? 37 LEU A C 1 ATOM 279 O O . LEU A 1 37 ? 18.407 -9.219 -14.784 1.00 20.03 ? 37 LEU A O 1 ATOM 280 C CB . LEU A 1 37 ? 17.296 -12.049 -16.215 1.00 20.32 ? 37 LEU A CB 1 ATOM 281 C CG . LEU A 1 37 ? 16.003 -11.416 -15.683 1.00 20.63 ? 37 LEU A CG 1 ATOM 282 C CD1 . LEU A 1 37 ? 15.478 -10.336 -16.640 1.00 19.77 ? 37 LEU A CD1 1 ATOM 283 C CD2 . LEU A 1 37 ? 14.973 -12.508 -15.460 1.00 21.74 ? 37 LEU A CD2 1 ATOM 284 N N . MET A 1 38 ? 19.050 -11.117 -13.757 1.00 19.74 ? 38 MET A N 1 ATOM 285 C CA . MET A 1 38 ? 19.224 -10.485 -12.441 1.00 20.85 ? 38 MET A CA 1 ATOM 286 C C . MET A 1 38 ? 20.330 -9.433 -12.428 1.00 21.03 ? 38 MET A C 1 ATOM 287 O O . MET A 1 38 ? 20.185 -8.406 -11.763 1.00 21.34 ? 38 MET A O 1 ATOM 288 C CB . MET A 1 38 ? 19.413 -11.530 -11.319 1.00 20.73 ? 38 MET A CB 1 ATOM 289 C CG . MET A 1 38 ? 18.210 -12.423 -11.123 1.00 21.36 ? 38 MET A CG 1 ATOM 290 S SD . MET A 1 38 ? 16.618 -11.557 -10.813 1.00 22.62 ? 38 MET A SD 1 ATOM 291 C CE . MET A 1 38 ? 16.987 -10.749 -9.244 1.00 20.58 ? 38 MET A CE 1 ATOM 292 N N . THR A 1 39 ? 21.419 -9.654 -13.179 1.00 20.84 ? 39 THR A N 1 ATOM 293 C CA . THR A 1 39 ? 22.474 -8.650 -13.278 1.00 20.47 ? 39 THR A CA 1 ATOM 294 C C . THR A 1 39 ? 21.899 -7.347 -13.856 1.00 20.62 ? 39 THR A C 1 ATOM 295 O O . THR A 1 39 ? 22.134 -6.270 -13.306 1.00 18.88 ? 39 THR A O 1 ATOM 296 C CB . THR A 1 39 ? 23.677 -9.161 -14.150 1.00 21.22 ? 39 THR A CB 1 ATOM 297 O OG1 . THR A 1 39 ? 24.324 -10.251 -13.484 1.00 22.83 ? 39 THR A OG1 1 ATOM 298 C CG2 . THR A 1 39 ? 24.692 -8.064 -14.417 1.00 21.73 ? 39 THR A CG2 1 ATOM 299 N N . LEU A 1 40 ? 21.131 -7.466 -14.940 1.00 20.42 ? 40 LEU A N 1 ATOM 300 C CA . LEU A 1 40 ? 20.452 -6.301 -15.560 1.00 21.49 ? 40 LEU A CA 1 ATOM 301 C C . LEU A 1 40 ? 19.388 -5.667 -14.647 1.00 20.95 ? 40 LEU A C 1 ATOM 302 O O . LEU A 1 40 ? 19.290 -4.442 -14.572 1.00 20.76 ? 40 LEU A O 1 ATOM 303 C CB . LEU A 1 40 ? 19.818 -6.687 -16.899 1.00 21.44 ? 40 LEU A CB 1 ATOM 304 C CG . LEU A 1 40 ? 20.794 -7.216 -17.962 1.00 23.69 ? 40 LEU A CG 1 ATOM 305 C CD1 . LEU A 1 40 ? 20.027 -8.013 -18.996 1.00 25.15 ? 40 LEU A CD1 1 ATOM 306 C CD2 . LEU A 1 40 ? 21.581 -6.076 -18.597 1.00 23.27 ? 40 LEU A CD2 1 ATOM 307 N N . LYS A 1 41 ? 18.603 -6.506 -13.972 1.00 20.80 ? 41 LYS A N 1 ATOM 308 C CA . LYS A 1 41 ? 17.570 -6.027 -13.043 1.00 20.52 ? 41 LYS A CA 1 ATOM 309 C C . LYS A 1 41 ? 18.201 -5.268 -11.876 1.00 20.74 ? 41 LYS A C 1 ATOM 310 O O . LYS A 1 41 ? 17.759 -4.185 -11.546 1.00 20.62 ? 41 LYS A O 1 ATOM 311 C CB . LYS A 1 41 ? 16.705 -7.176 -12.514 1.00 19.91 ? 41 LYS A CB 1 ATOM 312 C CG . LYS A 1 41 ? 15.751 -6.764 -11.356 1.00 19.84 ? 41 LYS A CG 1 ATOM 313 C CD . LYS A 1 41 ? 14.805 -7.914 -10.961 1.00 19.67 ? 41 LYS A CD 1 ATOM 314 C CE . LYS A 1 41 ? 14.027 -7.555 -9.699 1.00 20.99 ? 41 LYS A CE 1 ATOM 315 N NZ . LYS A 1 41 ? 12.928 -8.523 -9.436 1.00 20.88 ? 41 LYS A NZ 1 ATOM 316 N N . ILE A 1 42 ? 19.240 -5.839 -11.261 1.00 20.64 ? 42 ILE A N 1 ATOM 317 C CA . ILE A 1 42 ? 19.924 -5.168 -10.150 1.00 21.20 ? 42 ILE A CA 1 ATOM 318 C C . ILE A 1 42 ? 20.555 -3.828 -10.546 1.00 21.42 ? 42 ILE A C 1 ATOM 319 O O . ILE A 1 42 ? 20.467 -2.848 -9.786 1.00 21.59 ? 42 ILE A O 1 ATOM 320 C CB . ILE A 1 42 ? 20.952 -6.100 -9.473 1.00 21.22 ? 42 ILE A CB 1 ATOM 321 C CG1 . ILE A 1 42 ? 20.196 -7.119 -8.598 1.00 21.29 ? 42 ILE A CG1 1 ATOM 322 C CG2 . ILE A 1 42 ? 22.012 -5.286 -8.659 1.00 22.40 ? 42 ILE A CG2 1 ATOM 323 C CD1 . ILE A 1 42 ? 20.921 -8.436 -8.405 1.00 25.21 ? 42 ILE A CD1 1 ATOM 324 N N . ALA A 1 43 ? 21.199 -3.789 -11.712 1.00 20.76 ? 43 ALA A N 1 ATOM 325 C CA . ALA A 1 43 ? 21.749 -2.545 -12.265 1.00 21.08 ? 43 ALA A CA 1 ATOM 326 C C . ALA A 1 43 ? 20.679 -1.497 -12.564 1.00 21.28 ? 43 ALA A C 1 ATOM 327 O O . ALA A 1 43 ? 20.914 -0.282 -12.397 1.00 21.44 ? 43 ALA A O 1 ATOM 328 C CB . ALA A 1 43 ? 22.561 -2.849 -13.551 1.00 21.27 ? 43 ALA A CB 1 ATOM 329 N N . GLU A 1 44 ? 19.520 -1.928 -13.075 1.00 20.37 ? 44 GLU A N 1 ATOM 330 C CA . GLU A 1 44 ? 18.467 -0.944 -13.302 1.00 21.63 ? 44 GLU A CA 1 ATOM 331 C C . GLU A 1 44 ? 17.978 -0.417 -11.953 1.00 21.14 ? 44 GLU A C 1 ATOM 332 O O . GLU A 1 44 ? 17.756 0.777 -11.785 1.00 21.06 ? 44 GLU A O 1 ATOM 333 C CB . GLU A 1 44 ? 17.320 -1.522 -14.133 1.00 21.04 ? 44 GLU A CB 1 ATOM 334 C CG . GLU A 1 44 ? 17.694 -1.533 -15.610 1.00 24.31 ? 44 GLU A CG 1 ATOM 335 C CD . GLU A 1 44 ? 16.674 -2.214 -16.482 1.00 27.84 ? 44 GLU A CD 1 ATOM 336 O OE1 . GLU A 1 44 ? 15.463 -2.169 -16.133 1.00 29.21 ? 44 GLU A OE1 1 ATOM 337 O OE2 . GLU A 1 44 ? 17.104 -2.792 -17.519 1.00 29.39 ? 44 GLU A OE2 1 ATOM 338 N N . MET A 1 45 ? 17.841 -1.323 -10.999 1.00 22.54 ? 45 MET A N 1 ATOM 339 C CA . MET A 1 45 ? 17.361 -0.945 -9.663 1.00 25.16 ? 45 MET A CA 1 ATOM 340 C C . MET A 1 45 ? 18.344 -0.056 -8.915 1.00 25.03 ? 45 MET A C 1 ATOM 341 O O . MET A 1 45 ? 17.940 0.926 -8.289 1.00 25.73 ? 45 MET A O 1 ATOM 342 C CB . MET A 1 45 ? 16.931 -2.184 -8.850 1.00 25.70 ? 45 MET A CB 1 ATOM 343 C CG . MET A 1 45 ? 15.506 -2.622 -9.238 1.00 30.41 ? 45 MET A CG 1 ATOM 344 S SD . MET A 1 45 ? 14.796 -3.959 -8.250 1.00 44.94 ? 45 MET A SD 1 ATOM 345 C CE . MET A 1 45 ? 14.246 -3.028 -6.812 1.00 39.64 ? 45 MET A CE 1 ATOM 346 N N . LYS A 1 46 ? 19.634 -0.358 -9.020 1.00 25.66 ? 46 LYS A N 1 ATOM 347 C CA . LYS A 1 46 ? 20.634 0.500 -8.374 1.00 26.30 ? 46 LYS A CA 1 ATOM 348 C C . LYS A 1 46 ? 20.587 1.912 -8.896 1.00 25.18 ? 46 LYS A C 1 ATOM 349 O O . LYS A 1 46 ? 20.604 2.868 -8.102 1.00 24.40 ? 46 LYS A O 1 ATOM 350 C CB . LYS A 1 46 ? 22.046 -0.048 -8.499 1.00 26.93 ? 46 LYS A CB 1 ATOM 351 C CG . LYS A 1 46 ? 22.645 -0.447 -7.159 1.00 31.73 ? 46 LYS A CG 1 ATOM 352 C CD . LYS A 1 46 ? 22.241 -1.847 -6.696 1.00 35.77 ? 46 LYS A CD 1 ATOM 353 C CE . LYS A 1 46 ? 23.169 -2.299 -5.546 1.00 37.92 ? 46 LYS A CE 1 ATOM 354 N NZ . LYS A 1 46 ? 22.974 -3.715 -5.087 1.00 39.63 ? 46 LYS A NZ 1 ATOM 355 N N . GLU A 1 47 ? 20.494 2.046 -10.217 1.00 24.12 ? 47 GLU A N 1 ATOM 356 C CA . GLU A 1 47 ? 20.388 3.371 -10.840 1.00 23.98 ? 47 GLU A CA 1 ATOM 357 C C . GLU A 1 47 ? 19.100 4.106 -10.418 1.00 23.57 ? 47 GLU A C 1 ATOM 358 O O . GLU A 1 47 ? 19.105 5.329 -10.214 1.00 23.91 ? 47 GLU A O 1 ATOM 359 C CB . GLU A 1 47 ? 20.488 3.242 -12.367 1.00 24.12 ? 47 GLU A CB 1 ATOM 360 C CG . GLU A 1 47 ? 20.355 4.553 -13.161 1.00 27.57 ? 47 GLU A CG 1 ATOM 361 C CD . GLU A 1 47 ? 21.419 5.605 -12.820 1.00 31.61 ? 47 GLU A CD 1 ATOM 362 O OE1 . GLU A 1 47 ? 22.448 5.277 -12.179 1.00 32.57 ? 47 GLU A OE1 1 ATOM 363 O OE2 . GLU A 1 47 ? 21.210 6.779 -13.204 1.00 36.63 ? 47 GLU A OE2 1 ATOM 364 N N . ALA A 1 48 ? 17.998 3.366 -10.283 1.00 22.56 ? 48 ALA A N 1 ATOM 365 C CA . ALA A 1 48 ? 16.732 3.952 -9.837 1.00 22.41 ? 48 ALA A CA 1 ATOM 366 C C . ALA A 1 48 ? 16.816 4.412 -8.376 1.00 22.79 ? 48 ALA A C 1 ATOM 367 O O . ALA A 1 48 ? 16.285 5.454 -8.036 1.00 22.86 ? 48 ALA A O 1 ATOM 368 C CB . ALA A 1 48 ? 15.556 2.965 -10.043 1.00 21.91 ? 48 ALA A CB 1 ATOM 369 N N . MET A 1 49 ? 17.497 3.637 -7.529 1.00 22.82 ? 49 MET A N 1 ATOM 370 C CA . MET A 1 49 ? 17.742 4.034 -6.142 1.00 24.21 ? 49 MET A CA 1 ATOM 371 C C . MET A 1 49 ? 18.602 5.292 -6.012 1.00 25.02 ? 49 MET A C 1 ATOM 372 O O . MET A 1 49 ? 18.389 6.091 -5.102 1.00 24.90 ? 49 MET A O 1 ATOM 373 C CB . MET A 1 49 ? 18.348 2.877 -5.342 1.00 24.81 ? 49 MET A CB 1 ATOM 374 C CG . MET A 1 49 ? 17.468 1.622 -5.347 1.00 24.50 ? 49 MET A CG 1 ATOM 375 S SD . MET A 1 49 ? 18.117 0.204 -4.429 1.00 27.89 ? 49 MET A SD 1 ATOM 376 C CE . MET A 1 49 ? 17.828 0.764 -2.751 1.00 24.14 ? 49 MET A CE 1 ATOM 377 N N . ARG A 1 50 ? 19.558 5.473 -6.933 1.00 25.52 ? 50 ARG A N 1 ATOM 378 C CA . ARG A 1 50 ? 20.376 6.693 -7.001 1.00 25.78 ? 50 ARG A CA 1 ATOM 379 C C . ARG A 1 50 ? 19.540 7.930 -7.355 1.00 25.54 ? 50 ARG A C 1 ATOM 380 O O . ARG A 1 50 ? 19.637 8.940 -6.655 1.00 25.98 ? 50 ARG A O 1 ATOM 381 C CB . ARG A 1 50 ? 21.530 6.536 -8.008 1.00 25.50 ? 50 ARG A CB 1 ATOM 382 C CG . ARG A 1 50 ? 22.475 7.757 -8.094 1.00 28.08 ? 50 ARG A CG 1 ATOM 383 C CD . ARG A 1 50 ? 23.612 7.551 -9.123 1.00 28.52 ? 50 ARG A CD 1 ATOM 384 N NE . ARG A 1 50 ? 23.158 7.686 -10.507 1.00 30.60 ? 50 ARG A NE 1 ATOM 385 C CZ . ARG A 1 50 ? 22.995 8.849 -11.136 1.00 33.48 ? 50 ARG A CZ 1 ATOM 386 N NH1 . ARG A 1 50 ? 23.255 9.994 -10.511 1.00 34.90 ? 50 ARG A NH1 1 ATOM 387 N NH2 . ARG A 1 50 ? 22.566 8.879 -12.386 1.00 34.16 ? 50 ARG A NH2 1 ATOM 388 N N . THR A 1 51 ? 18.703 7.841 -8.404 1.00 24.26 ? 51 THR A N 1 ATOM 389 C CA . THR A 1 51 ? 18.001 9.017 -8.945 1.00 23.51 ? 51 THR A CA 1 ATOM 390 C C . THR A 1 51 ? 16.547 9.167 -8.504 1.00 23.05 ? 51 THR A C 1 ATOM 391 O O . THR A 1 51 ? 15.951 10.236 -8.658 1.00 22.17 ? 51 THR A O 1 ATOM 392 C CB . THR A 1 51 ? 17.963 9.007 -10.492 1.00 24.31 ? 51 THR A CB 1 ATOM 393 O OG1 . THR A 1 51 ? 17.309 7.816 -10.956 1.00 24.06 ? 51 THR A OG1 1 ATOM 394 C CG2 . THR A 1 51 ? 19.376 9.087 -11.088 1.00 25.53 ? 51 THR A CG2 1 ATOM 395 N N . LEU A 1 52 ? 15.978 8.087 -7.980 1.00 22.15 ? 52 LEU A N 1 ATOM 396 C CA . LEU A 1 52 ? 14.532 8.000 -7.719 1.00 21.97 ? 52 LEU A CA 1 ATOM 397 C C . LEU A 1 52 ? 13.691 8.077 -8.992 1.00 22.42 ? 52 LEU A C 1 ATOM 398 O O . LEU A 1 52 ? 12.484 8.288 -8.923 1.00 23.63 ? 52 LEU A O 1 ATOM 399 C CB . LEU A 1 52 ? 14.063 9.014 -6.677 1.00 21.25 ? 52 LEU A CB 1 ATOM 400 C CG . LEU A 1 52 ? 14.868 9.008 -5.380 1.00 20.35 ? 52 LEU A CG 1 ATOM 401 C CD1 . LEU A 1 52 ? 14.206 9.964 -4.361 1.00 21.20 ? 52 LEU A CD1 1 ATOM 402 C CD2 . LEU A 1 52 ? 14.932 7.570 -4.813 1.00 20.46 ? 52 LEU A CD2 1 ATOM 403 N N . ILE A 1 53 ? 14.310 7.870 -10.150 1.00 21.77 ? 53 ILE A N 1 ATOM 404 C CA . ILE A 1 53 ? 13.528 7.671 -11.372 1.00 21.30 ? 53 ILE A CA 1 ATOM 405 C C . ILE A 1 53 ? 13.261 6.168 -11.475 1.00 21.21 ? 53 ILE A C 1 ATOM 406 O O . ILE A 1 53 ? 14.116 5.409 -11.943 1.00 22.09 ? 53 ILE A O 1 ATOM 407 C CB . ILE A 1 53 ? 14.256 8.233 -12.629 1.00 21.66 ? 53 ILE A CB 1 ATOM 408 C CG1 . ILE A 1 53 ? 14.487 9.746 -12.475 1.00 22.68 ? 53 ILE A CG1 1 ATOM 409 C CG2 . ILE A 1 53 ? 13.484 7.916 -13.916 1.00 20.21 ? 53 ILE A CG2 1 ATOM 410 C CD1 . ILE A 1 53 ? 15.690 10.303 -13.360 1.00 26.75 ? 53 ILE A CD1 1 ATOM 411 N N . PHE A 1 54 ? 12.093 5.738 -10.988 1.00 18.96 ? 54 PHE A N 1 ATOM 412 C CA . PHE A 1 54 ? 11.778 4.316 -10.896 1.00 18.17 ? 54 PHE A CA 1 ATOM 413 C C . PHE A 1 54 ? 10.413 4.084 -11.508 1.00 16.39 ? 54 PHE A C 1 ATOM 414 O O . PHE A 1 54 ? 9.389 4.447 -10.910 1.00 16.52 ? 54 PHE A O 1 ATOM 415 C CB . PHE A 1 54 ? 11.835 3.797 -9.445 1.00 18.79 ? 54 PHE A CB 1 ATOM 416 C CG . PHE A 1 54 ? 11.640 2.284 -9.328 1.00 18.98 ? 54 PHE A CG 1 ATOM 417 C CD1 . PHE A 1 54 ? 12.461 1.403 -10.042 1.00 20.97 ? 54 PHE A CD1 1 ATOM 418 C CD2 . PHE A 1 54 ? 10.661 1.750 -8.493 1.00 18.26 ? 54 PHE A CD2 1 ATOM 419 C CE1 . PHE A 1 54 ? 12.295 0.004 -9.952 1.00 18.35 ? 54 PHE A CE1 1 ATOM 420 C CE2 . PHE A 1 54 ? 10.490 0.346 -8.387 1.00 17.83 ? 54 PHE A CE2 1 ATOM 421 C CZ . PHE A 1 54 ? 11.318 -0.522 -9.112 1.00 19.53 ? 54 PHE A CZ 1 ATOM 422 N N . PRO A 1 55 ? 10.392 3.503 -12.718 1.00 15.08 ? 55 PRO A N 1 ATOM 423 C CA . PRO A 1 55 ? 9.135 3.529 -13.475 1.00 14.98 ? 55 PRO A CA 1 ATOM 424 C C . PRO A 1 55 ? 7.878 3.009 -12.728 1.00 14.36 ? 55 PRO A C 1 ATOM 425 O O . PRO A 1 55 ? 6.850 3.678 -12.792 1.00 15.52 ? 55 PRO A O 1 ATOM 426 C CB . PRO A 1 55 ? 9.484 2.764 -14.772 1.00 13.79 ? 55 PRO A CB 1 ATOM 427 C CG . PRO A 1 55 ? 11.012 3.097 -14.937 1.00 16.36 ? 55 PRO A CG 1 ATOM 428 C CD . PRO A 1 55 ? 11.541 3.048 -13.536 1.00 14.16 ? 55 PRO A CD 1 ATOM 429 N N . PRO A 1 56 ? 7.953 1.860 -12.005 1.00 14.61 ? 56 PRO A N 1 ATOM 430 C CA . PRO A 1 56 ? 6.734 1.426 -11.272 1.00 14.99 ? 56 PRO A CA 1 ATOM 431 C C . PRO A 1 56 ? 6.228 2.412 -10.212 1.00 15.11 ? 56 PRO A C 1 ATOM 432 O O . PRO A 1 56 ? 5.056 2.350 -9.868 1.00 15.64 ? 56 PRO A O 1 ATOM 433 C CB . PRO A 1 56 ? 7.164 0.091 -10.595 1.00 14.27 ? 56 PRO A CB 1 ATOM 434 C CG . PRO A 1 56 ? 8.385 -0.382 -11.444 1.00 15.11 ? 56 PRO A CG 1 ATOM 435 C CD . PRO A 1 56 ? 9.081 0.936 -11.759 1.00 14.66 ? 56 PRO A CD 1 ATOM 436 N N . SER A 1 57 ? 7.094 3.297 -9.709 1.00 15.20 ? 57 SER A N 1 ATOM 437 C CA . SER A 1 57 ? 6.708 4.294 -8.722 1.00 16.79 ? 57 SER A CA 1 ATOM 438 C C . SER A 1 57 ? 6.157 5.577 -9.374 1.00 16.73 ? 57 SER A C 1 ATOM 439 O O . SER A 1 57 ? 5.688 6.461 -8.678 1.00 17.93 ? 57 SER A O 1 ATOM 440 C CB . SER A 1 57 ? 7.900 4.640 -7.796 1.00 16.81 ? 57 SER A CB 1 ATOM 441 O OG . SER A 1 57 ? 8.869 5.404 -8.506 1.00 20.02 ? 57 SER A OG 1 ATOM 442 N N . MET A 1 58 ? 6.242 5.680 -10.694 1.00 16.05 ? 58 MET A N 1 ATOM 443 C CA . MET A 1 58 ? 5.676 6.813 -11.442 1.00 16.76 ? 58 MET A CA 1 ATOM 444 C C . MET A 1 58 ? 4.371 6.378 -12.098 1.00 15.88 ? 58 MET A C 1 ATOM 445 O O . MET A 1 58 ? 4.145 5.178 -12.266 1.00 16.53 ? 58 MET A O 1 ATOM 446 C CB . MET A 1 58 ? 6.654 7.275 -12.539 1.00 17.25 ? 58 MET A CB 1 ATOM 447 C CG . MET A 1 58 ? 8.029 7.623 -12.007 1.00 20.46 ? 58 MET A CG 1 ATOM 448 S SD . MET A 1 58 ? 9.248 7.687 -13.347 1.00 27.68 ? 58 MET A SD 1 ATOM 449 C CE . MET A 1 58 ? 10.525 8.447 -12.371 1.00 31.83 ? 58 MET A CE 1 ATOM 450 N N . HIS A 1 59 ? 3.529 7.337 -12.486 1.00 15.69 ? 59 HIS A N 1 ATOM 451 C CA . HIS A 1 59 ? 2.292 7.037 -13.221 1.00 15.43 ? 59 HIS A CA 1 ATOM 452 C C . HIS A 1 59 ? 2.670 6.439 -14.575 1.00 16.29 ? 59 HIS A C 1 ATOM 453 O O . HIS A 1 59 ? 3.578 6.966 -15.263 1.00 16.32 ? 59 HIS A O 1 ATOM 454 C CB . HIS A 1 59 ? 1.437 8.289 -13.427 1.00 15.55 ? 59 HIS A CB 1 ATOM 455 C CG . HIS A 1 59 ? 0.041 7.991 -13.888 1.00 15.67 ? 59 HIS A CG 1 ATOM 456 N ND1 . HIS A 1 59 ? -0.244 7.530 -15.156 1.00 14.81 ? 59 HIS A ND1 1 ATOM 457 C CD2 . HIS A 1 59 ? -1.148 8.078 -13.240 1.00 14.72 ? 59 HIS A CD2 1 ATOM 458 C CE1 . HIS A 1 59 ? -1.549 7.337 -15.270 1.00 17.05 ? 59 HIS A CE1 1 ATOM 459 N NE2 . HIS A 1 59 ? -2.122 7.662 -14.119 1.00 17.17 ? 59 HIS A NE2 1 ATOM 460 N N . PHE A 1 60 ? 2.013 5.329 -14.936 1.00 16.19 ? 60 PHE A N 1 ATOM 461 C CA . PHE A 1 60 ? 2.322 4.617 -16.192 1.00 15.84 ? 60 PHE A CA 1 ATOM 462 C C . PHE A 1 60 ? 2.391 5.516 -17.469 1.00 16.73 ? 60 PHE A C 1 ATOM 463 O O . PHE A 1 60 ? 3.245 5.267 -18.366 1.00 16.73 ? 60 PHE A O 1 ATOM 464 C CB . PHE A 1 60 ? 1.384 3.412 -16.409 1.00 15.43 ? 60 PHE A CB 1 ATOM 465 C CG . PHE A 1 60 ? 1.682 2.633 -17.672 1.00 14.14 ? 60 PHE A CG 1 ATOM 466 C CD1 . PHE A 1 60 ? 2.822 1.873 -17.764 1.00 13.74 ? 60 PHE A CD1 1 ATOM 467 C CD2 . PHE A 1 60 ? 0.838 2.721 -18.778 1.00 13.57 ? 60 PHE A CD2 1 ATOM 468 C CE1 . PHE A 1 60 ? 3.117 1.159 -18.964 1.00 15.54 ? 60 PHE A CE1 1 ATOM 469 C CE2 . PHE A 1 60 ? 1.118 2.031 -19.993 1.00 13.74 ? 60 PHE A CE2 1 ATOM 470 C CZ . PHE A 1 60 ? 2.263 1.255 -20.075 1.00 16.80 ? 60 PHE A CZ 1 ATOM 471 N N . PHE A 1 61 ? 1.531 6.540 -17.551 1.00 16.51 ? 61 PHE A N 1 ATOM 472 C CA . PHE A 1 61 ? 1.547 7.454 -18.718 1.00 17.73 ? 61 PHE A CA 1 ATOM 473 C C . PHE A 1 61 ? 2.902 8.148 -18.876 1.00 18.34 ? 61 PHE A C 1 ATOM 474 O O . PHE A 1 61 ? 3.364 8.399 -19.988 1.00 19.17 ? 61 PHE A O 1 ATOM 475 C CB . PHE A 1 61 ? 0.452 8.543 -18.643 1.00 17.48 ? 61 PHE A CB 1 ATOM 476 C CG . PHE A 1 61 ? -0.964 8.012 -18.589 1.00 17.14 ? 61 PHE A CG 1 ATOM 477 C CD1 . PHE A 1 61 ? -1.261 6.709 -18.966 1.00 17.77 ? 61 PHE A CD1 1 ATOM 478 C CD2 . PHE A 1 61 ? -1.996 8.839 -18.143 1.00 17.06 ? 61 PHE A CD2 1 ATOM 479 C CE1 . PHE A 1 61 ? -2.561 6.231 -18.889 1.00 17.43 ? 61 PHE A CE1 1 ATOM 480 C CE2 . PHE A 1 61 ? -3.316 8.380 -18.079 1.00 16.27 ? 61 PHE A CE2 1 ATOM 481 C CZ . PHE A 1 61 ? -3.596 7.070 -18.451 1.00 18.48 ? 61 PHE A CZ 1 ATOM 482 N N . GLN A 1 62 ? 3.530 8.474 -17.759 1.00 19.30 ? 62 GLN A N 1 ATOM 483 C CA . GLN A 1 62 ? 4.834 9.116 -17.775 1.00 19.04 ? 62 GLN A CA 1 ATOM 484 C C . GLN A 1 62 ? 5.963 8.099 -17.684 1.00 19.96 ? 62 GLN A C 1 ATOM 485 O O . GLN A 1 62 ? 7.095 8.416 -18.064 1.00 21.38 ? 62 GLN A O 1 ATOM 486 C CB . GLN A 1 62 ? 4.924 10.146 -16.625 1.00 19.32 ? 62 GLN A CB 1 ATOM 487 C CG . GLN A 1 62 ? 4.182 11.504 -16.881 1.00 20.12 ? 62 GLN A CG 1 ATOM 488 C CD . GLN A 1 62 ? 2.682 11.348 -17.159 1.00 21.09 ? 62 GLN A CD 1 ATOM 489 O OE1 . GLN A 1 62 ? 2.196 11.631 -18.268 1.00 23.47 ? 62 GLN A OE1 1 ATOM 490 N NE2 . GLN A 1 62 ? 1.943 10.881 -16.160 1.00 17.50 ? 62 GLN A NE2 1 ATOM 491 N N . ALA A 1 63 ? 5.683 6.893 -17.176 1.00 18.58 ? 63 ALA A N 1 ATOM 492 C CA . ALA A 1 63 ? 6.724 5.860 -17.027 1.00 18.92 ? 63 ALA A CA 1 ATOM 493 C C . ALA A 1 63 ? 6.959 5.034 -18.307 1.00 18.66 ? 63 ALA A C 1 ATOM 494 O O . ALA A 1 63 ? 8.039 4.445 -18.474 1.00 17.91 ? 63 ALA A O 1 ATOM 495 C CB . ALA A 1 63 ? 6.393 4.917 -15.898 1.00 17.91 ? 63 ALA A CB 1 ATOM 496 N N . LYS A 1 64 ? 5.948 4.986 -19.171 1.00 18.59 ? 64 LYS A N 1 ATOM 497 C CA . LYS A 1 64 ? 5.951 4.104 -20.339 1.00 19.76 ? 64 LYS A CA 1 ATOM 498 C C . LYS A 1 64 ? 7.207 4.232 -21.201 1.00 19.97 ? 64 LYS A C 1 ATOM 499 O O . LYS A 1 64 ? 7.837 3.223 -21.522 1.00 20.67 ? 64 LYS A O 1 ATOM 500 C CB . LYS A 1 64 ? 4.709 4.328 -21.212 1.00 18.66 ? 64 LYS A CB 1 ATOM 501 C CG . LYS A 1 64 ? 4.654 3.399 -22.453 1.00 21.38 ? 64 LYS A CG 1 ATOM 502 C CD . LYS A 1 64 ? 3.484 3.767 -23.334 1.00 24.31 ? 64 LYS A CD 1 ATOM 503 C CE . LYS A 1 64 ? 3.425 2.882 -24.548 1.00 28.80 ? 64 LYS A CE 1 ATOM 504 N NZ . LYS A 1 64 ? 2.509 3.498 -25.534 1.00 29.21 ? 64 LYS A NZ 1 ATOM 505 N N . HIS A 1 65 ? 7.548 5.465 -21.586 1.00 20.24 ? 65 HIS A N 1 ATOM 506 C CA . HIS A 1 65 ? 8.699 5.674 -22.459 1.00 21.59 ? 65 HIS A CA 1 ATOM 507 C C . HIS A 1 65 ? 10.007 5.162 -21.825 1.00 20.58 ? 65 HIS A C 1 ATOM 508 O O . HIS A 1 65 ? 10.895 4.706 -22.530 1.00 20.15 ? 65 HIS A O 1 ATOM 509 C CB . HIS A 1 65 ? 8.805 7.141 -22.913 1.00 21.78 ? 65 HIS A CB 1 ATOM 510 C CG . HIS A 1 65 ? 9.266 8.085 -21.839 1.00 25.64 ? 65 HIS A CG 1 ATOM 511 N ND1 . HIS A 1 65 ? 10.589 8.458 -21.691 1.00 28.55 ? 65 HIS A ND1 1 ATOM 512 C CD2 . HIS A 1 65 ? 8.583 8.737 -20.868 1.00 27.20 ? 65 HIS A CD2 1 ATOM 513 C CE1 . HIS A 1 65 ? 10.700 9.300 -20.679 1.00 29.15 ? 65 HIS A CE1 1 ATOM 514 N NE2 . HIS A 1 65 ? 9.499 9.483 -20.158 1.00 30.61 ? 65 HIS A NE2 1 ATOM 515 N N . LEU A 1 66 ? 10.092 5.206 -20.494 1.00 20.27 ? 66 LEU A N 1 ATOM 516 C CA . LEU A 1 66 ? 11.254 4.702 -19.772 1.00 20.65 ? 66 LEU A CA 1 ATOM 517 C C . LEU A 1 66 ? 11.250 3.190 -19.716 1.00 19.82 ? 66 LEU A C 1 ATOM 518 O O . LEU A 1 66 ? 12.300 2.561 -19.784 1.00 20.09 ? 66 LEU A O 1 ATOM 519 C CB . LEU A 1 66 ? 11.313 5.267 -18.339 1.00 20.84 ? 66 LEU A CB 1 ATOM 520 C CG . LEU A 1 66 ? 11.518 6.774 -18.176 1.00 23.98 ? 66 LEU A CG 1 ATOM 521 C CD1 . LEU A 1 66 ? 11.219 7.207 -16.718 1.00 25.31 ? 66 LEU A CD1 1 ATOM 522 C CD2 . LEU A 1 66 ? 12.938 7.187 -18.583 1.00 25.65 ? 66 LEU A CD2 1 ATOM 523 N N . ILE A 1 67 ? 10.062 2.600 -19.570 1.00 19.52 ? 67 ILE A N 1 ATOM 524 C CA . ILE A 1 67 ? 9.938 1.138 -19.503 1.00 18.11 ? 67 ILE A CA 1 ATOM 525 C C . ILE A 1 67 ? 10.395 0.562 -20.834 1.00 18.94 ? 67 ILE A C 1 ATOM 526 O O . ILE A 1 67 ? 11.031 -0.492 -20.872 1.00 17.86 ? 67 ILE A O 1 ATOM 527 C CB . ILE A 1 67 ? 8.480 0.681 -19.165 1.00 18.18 ? 67 ILE A CB 1 ATOM 528 C CG1 . ILE A 1 67 ? 8.143 1.042 -17.704 1.00 16.17 ? 67 ILE A CG1 1 ATOM 529 C CG2 . ILE A 1 67 ? 8.272 -0.824 -19.425 1.00 14.96 ? 67 ILE A CG2 1 ATOM 530 C CD1 . ILE A 1 67 ? 6.640 0.961 -17.319 1.00 14.89 ? 67 ILE A CD1 1 ATOM 531 N N . GLU A 1 68 ? 10.078 1.278 -21.911 1.00 19.73 ? 68 GLU A N 1 ATOM 532 C CA . GLU A 1 68 ? 10.395 0.812 -23.272 1.00 21.94 ? 68 GLU A CA 1 ATOM 533 C C . GLU A 1 68 ? 11.896 0.797 -23.570 1.00 21.66 ? 68 GLU A C 1 ATOM 534 O O . GLU A 1 68 ? 12.351 0.109 -24.462 1.00 21.23 ? 68 GLU A O 1 ATOM 535 C CB . GLU A 1 68 ? 9.608 1.639 -24.298 1.00 21.56 ? 68 GLU A CB 1 ATOM 536 C CG . GLU A 1 68 ? 8.181 1.142 -24.371 1.00 24.73 ? 68 GLU A CG 1 ATOM 537 C CD . GLU A 1 68 ? 7.249 2.078 -25.108 1.00 28.91 ? 68 GLU A CD 1 ATOM 538 O OE1 . GLU A 1 68 ? 7.638 3.225 -25.410 1.00 30.82 ? 68 GLU A OE1 1 ATOM 539 O OE2 . GLU A 1 68 ? 6.115 1.657 -25.381 1.00 31.62 ? 68 GLU A OE2 1 ATOM 540 N N . ARG A 1 69 ? 12.645 1.553 -22.785 1.00 23.13 ? 69 ARG A N 1 ATOM 541 C CA . ARG A 1 69 ? 14.099 1.616 -22.882 1.00 24.05 ? 69 ARG A CA 1 ATOM 542 C C . ARG A 1 69 ? 14.790 0.659 -21.920 1.00 23.29 ? 69 ARG A C 1 ATOM 543 O O . ARG A 1 69 ? 16.004 0.628 -21.868 1.00 23.82 ? 69 ARG A O 1 ATOM 544 C CB . ARG A 1 69 ? 14.555 3.044 -22.610 1.00 24.82 ? 69 ARG A CB 1 ATOM 545 C CG . ARG A 1 69 ? 14.392 3.931 -23.835 1.00 29.38 ? 69 ARG A CG 1 ATOM 546 C CD . ARG A 1 69 ? 14.120 5.395 -23.500 1.00 36.97 ? 69 ARG A CD 1 ATOM 547 N NE . ARG A 1 69 ? 14.964 5.966 -22.446 1.00 43.03 ? 69 ARG A NE 1 ATOM 548 C CZ . ARG A 1 69 ? 14.946 7.257 -22.095 1.00 45.68 ? 69 ARG A CZ 1 ATOM 549 N NH1 . ARG A 1 69 ? 14.141 8.118 -22.719 1.00 46.44 ? 69 ARG A NH1 1 ATOM 550 N NH2 . ARG A 1 69 ? 15.739 7.694 -21.125 1.00 46.32 ? 69 ARG A NH2 1 ATOM 551 N N . SER A 1 70 ? 14.014 -0.106 -21.149 1.00 22.08 ? 70 SER A N 1 ATOM 552 C CA . SER A 1 70 ? 14.568 -1.029 -20.147 1.00 20.42 ? 70 SER A CA 1 ATOM 553 C C . SER A 1 70 ? 14.992 -2.345 -20.792 1.00 20.83 ? 70 SER A C 1 ATOM 554 O O . SER A 1 70 ? 14.273 -2.904 -21.626 1.00 19.55 ? 70 SER A O 1 ATOM 555 C CB . SER A 1 70 ? 13.556 -1.270 -19.011 1.00 19.91 ? 70 SER A CB 1 ATOM 556 O OG . SER A 1 70 ? 13.875 -2.442 -18.269 1.00 19.28 ? 70 SER A OG 1 ATOM 557 N N . GLN A 1 71 ? 16.184 -2.821 -20.414 1.00 21.48 ? 71 GLN A N 1 ATOM 558 C CA . GLN A 1 71 ? 16.708 -4.099 -20.891 1.00 21.96 ? 71 GLN A CA 1 ATOM 559 C C . GLN A 1 71 ? 15.925 -5.259 -20.282 1.00 21.26 ? 71 GLN A C 1 ATOM 560 O O . GLN A 1 71 ? 15.798 -6.326 -20.899 1.00 21.18 ? 71 GLN A O 1 ATOM 561 C CB . GLN A 1 71 ? 18.216 -4.239 -20.565 1.00 22.30 ? 71 GLN A CB 1 ATOM 562 C CG . GLN A 1 71 ? 19.088 -3.165 -21.250 1.00 25.06 ? 71 GLN A CG 1 ATOM 563 C CD . GLN A 1 71 ? 19.231 -3.384 -22.733 1.00 30.64 ? 71 GLN A CD 1 ATOM 564 O OE1 . GLN A 1 71 ? 18.949 -4.472 -23.249 1.00 34.48 ? 71 GLN A OE1 1 ATOM 565 N NE2 . GLN A 1 71 ? 19.677 -2.351 -23.442 1.00 33.59 ? 71 GLN A NE2 1 ATOM 566 N N . VAL A 1 72 ? 15.431 -5.058 -19.066 1.00 20.01 ? 72 VAL A N 1 ATOM 567 C CA . VAL A 1 72 ? 14.509 -6.021 -18.435 1.00 18.75 ? 72 VAL A CA 1 ATOM 568 C C . VAL A 1 72 ? 13.177 -6.104 -19.202 1.00 19.02 ? 72 VAL A C 1 ATOM 569 O O . VAL A 1 72 ? 12.690 -7.196 -19.465 1.00 19.12 ? 72 VAL A O 1 ATOM 570 C CB . VAL A 1 72 ? 14.273 -5.693 -16.928 1.00 19.46 ? 72 VAL A CB 1 ATOM 571 C CG1 . VAL A 1 72 ? 13.133 -6.539 -16.331 1.00 17.65 ? 72 VAL A CG1 1 ATOM 572 C CG2 . VAL A 1 72 ? 15.557 -5.914 -16.104 1.00 18.16 ? 72 VAL A CG2 1 ATOM 573 N N . PHE A 1 73 ? 12.599 -4.953 -19.564 1.00 19.05 ? 73 PHE A N 1 ATOM 574 C CA . PHE A 1 73 ? 11.419 -4.926 -20.415 1.00 19.74 ? 73 PHE A CA 1 ATOM 575 C C . PHE A 1 73 ? 11.630 -5.671 -21.752 1.00 20.22 ? 73 PHE A C 1 ATOM 576 O O . PHE A 1 73 ? 10.767 -6.414 -22.178 1.00 19.58 ? 73 PHE A O 1 ATOM 577 C CB . PHE A 1 73 ? 10.950 -3.482 -20.692 1.00 18.89 ? 73 PHE A CB 1 ATOM 578 C CG . PHE A 1 73 ? 9.720 -3.415 -21.577 1.00 20.34 ? 73 PHE A CG 1 ATOM 579 C CD1 . PHE A 1 73 ? 8.469 -3.840 -21.088 1.00 20.47 ? 73 PHE A CD1 1 ATOM 580 C CD2 . PHE A 1 73 ? 9.815 -2.979 -22.913 1.00 19.77 ? 73 PHE A CD2 1 ATOM 581 C CE1 . PHE A 1 73 ? 7.325 -3.792 -21.896 1.00 20.32 ? 73 PHE A CE1 1 ATOM 582 C CE2 . PHE A 1 73 ? 8.686 -2.943 -23.739 1.00 23.02 ? 73 PHE A CE2 1 ATOM 583 C CZ . PHE A 1 73 ? 7.432 -3.358 -23.232 1.00 22.03 ? 73 PHE A CZ 1 ATOM 584 N N . ASN A 1 74 ? 12.803 -5.484 -22.365 1.00 21.75 ? 74 ASN A N 1 ATOM 585 C CA . ASN A 1 74 ? 13.147 -6.164 -23.624 1.00 22.78 ? 74 ASN A CA 1 ATOM 586 C C . ASN A 1 74 ? 13.129 -7.681 -23.459 1.00 21.85 ? 74 ASN A C 1 ATOM 587 O O . ASN A 1 74 ? 12.558 -8.384 -24.289 1.00 22.09 ? 74 ASN A O 1 ATOM 588 C CB . ASN A 1 74 ? 14.490 -5.664 -24.194 1.00 23.00 ? 74 ASN A CB 1 ATOM 589 C CG . ASN A 1 74 ? 14.780 -6.220 -25.592 1.00 27.27 ? 74 ASN A CG 1 ATOM 590 O OD1 . ASN A 1 74 ? 13.959 -6.086 -26.517 1.00 31.24 ? 74 ASN A OD1 1 ATOM 591 N ND2 . ASN A 1 74 ? 15.954 -6.833 -25.757 1.00 30.38 ? 74 ASN A ND2 1 ATOM 592 N N . ILE A 1 75 ? 13.705 -8.176 -22.366 1.00 20.88 ? 75 ILE A N 1 ATOM 593 C CA . ILE A 1 75 ? 13.677 -9.611 -22.055 1.00 19.01 ? 75 ILE A CA 1 ATOM 594 C C . ILE A 1 75 ? 12.234 -10.107 -21.769 1.00 19.54 ? 75 ILE A C 1 ATOM 595 O O . ILE A 1 75 ? 11.813 -11.176 -22.243 1.00 18.93 ? 75 ILE A O 1 ATOM 596 C CB . ILE A 1 75 ? 14.660 -9.939 -20.901 1.00 19.14 ? 75 ILE A CB 1 ATOM 597 C CG1 . ILE A 1 75 ? 16.123 -9.791 -21.365 1.00 19.43 ? 75 ILE A CG1 1 ATOM 598 C CG2 . ILE A 1 75 ? 14.454 -11.327 -20.354 1.00 16.45 ? 75 ILE A CG2 1 ATOM 599 C CD1 . ILE A 1 75 ? 17.032 -9.404 -20.248 1.00 16.38 ? 75 ILE A CD1 1 ATOM 600 N N . LEU A 1 76 ? 11.458 -9.318 -21.030 1.00 18.96 ? 76 LEU A N 1 ATOM 601 C CA . LEU A 1 76 ? 10.058 -9.712 -20.730 1.00 19.03 ? 76 LEU A CA 1 ATOM 602 C C . LEU A 1 76 ? 9.176 -9.795 -21.975 1.00 19.26 ? 76 LEU A C 1 ATOM 603 O O . LEU A 1 76 ? 8.302 -10.660 -22.074 1.00 19.37 ? 76 LEU A O 1 ATOM 604 C CB . LEU A 1 76 ? 9.453 -8.761 -19.682 1.00 18.61 ? 76 LEU A CB 1 ATOM 605 C CG . LEU A 1 76 ? 10.065 -8.876 -18.290 1.00 19.76 ? 76 LEU A CG 1 ATOM 606 C CD1 . LEU A 1 76 ? 9.432 -7.852 -17.337 1.00 21.53 ? 76 LEU A CD1 1 ATOM 607 C CD2 . LEU A 1 76 ? 9.893 -10.280 -17.725 1.00 18.35 ? 76 LEU A CD2 1 ATOM 608 N N . ARG A 1 77 ? 9.397 -8.878 -22.910 1.00 20.66 ? 77 ARG A N 1 ATOM 609 C CA . ARG A 1 77 ? 8.763 -8.900 -24.223 1.00 22.04 ? 77 ARG A CA 1 ATOM 610 C C . ARG A 1 77 ? 8.936 -10.214 -24.989 1.00 22.52 ? 77 ARG A C 1 ATOM 611 O O . ARG A 1 77 ? 7.967 -10.710 -25.598 1.00 21.21 ? 77 ARG A O 1 ATOM 612 C CB . ARG A 1 77 ? 9.318 -7.760 -25.072 1.00 23.18 ? 77 ARG A CB 1 ATOM 613 C CG . ARG A 1 77 ? 8.599 -6.462 -24.871 1.00 24.39 ? 77 ARG A CG 1 ATOM 614 C CD . ARG A 1 77 ? 7.348 -6.433 -25.693 1.00 29.34 ? 77 ARG A CD 1 ATOM 615 N NE . ARG A 1 77 ? 7.659 -6.290 -27.115 1.00 32.83 ? 77 ARG A NE 1 ATOM 616 C CZ . ARG A 1 77 ? 6.804 -6.524 -28.117 1.00 36.23 ? 77 ARG A CZ 1 ATOM 617 N NH1 . ARG A 1 77 ? 5.548 -6.928 -27.889 1.00 35.18 ? 77 ARG A NH1 1 ATOM 618 N NH2 . ARG A 1 77 ? 7.217 -6.360 -29.371 1.00 37.72 ? 77 ARG A NH2 1 ATOM 619 N N . MET A 1 78 ? 10.172 -10.741 -24.952 1.00 21.95 ? 78 MET A N 1 ATOM 620 C CA . MET A 1 78 ? 10.584 -12.001 -25.597 1.00 22.17 ? 78 MET A CA 1 ATOM 621 C C . MET A 1 78 ? 10.100 -13.241 -24.858 1.00 20.94 ? 78 MET A C 1 ATOM 622 O O . MET A 1 78 ? 10.008 -14.310 -25.446 1.00 20.09 ? 78 MET A O 1 ATOM 623 C CB . MET A 1 78 ? 12.125 -12.111 -25.625 1.00 22.98 ? 78 MET A CB 1 ATOM 624 C CG . MET A 1 78 ? 12.848 -11.134 -26.542 1.00 27.40 ? 78 MET A CG 1 ATOM 625 S SD . MET A 1 78 ? 14.599 -10.924 -26.085 1.00 38.92 ? 78 MET A SD 1 ATOM 626 C CE . MET A 1 78 ? 15.215 -12.607 -26.004 1.00 34.55 ? 78 MET A CE 1 ATOM 627 N N . MET A 1 79 ? 9.842 -13.104 -23.563 1.00 19.53 ? 79 MET A N 1 ATOM 628 C CA . MET A 1 79 ? 9.391 -14.227 -22.748 1.00 20.25 ? 79 MET A CA 1 ATOM 629 C C . MET A 1 79 ? 8.031 -14.783 -23.208 1.00 18.98 ? 79 MET A C 1 ATOM 630 O O . MET A 1 79 ? 7.110 -14.003 -23.429 1.00 19.20 ? 79 MET A O 1 ATOM 631 C CB . MET A 1 79 ? 9.298 -13.812 -21.262 1.00 20.40 ? 79 MET A CB 1 ATOM 632 C CG . MET A 1 79 ? 9.113 -15.007 -20.339 1.00 22.48 ? 79 MET A CG 1 ATOM 633 S SD . MET A 1 79 ? 9.181 -14.539 -18.611 1.00 29.52 ? 79 MET A SD 1 ATOM 634 C CE . MET A 1 79 ? 7.538 -13.919 -18.408 1.00 23.63 ? 79 MET A CE 1 ATOM 635 N N . PRO A 1 80 ? 7.910 -16.123 -23.362 1.00 19.02 ? 80 PRO A N 1 ATOM 636 C CA . PRO A 1 80 ? 6.553 -16.676 -23.544 1.00 19.27 ? 80 PRO A CA 1 ATOM 637 C C . PRO A 1 80 ? 5.850 -16.642 -22.201 1.00 19.29 ? 80 PRO A C 1 ATOM 638 O O . PRO A 1 80 ? 6.251 -17.350 -21.273 1.00 18.81 ? 80 PRO A O 1 ATOM 639 C CB . PRO A 1 80 ? 6.797 -18.120 -23.971 1.00 19.82 ? 80 PRO A CB 1 ATOM 640 C CG . PRO A 1 80 ? 8.169 -18.474 -23.376 1.00 19.22 ? 80 PRO A CG 1 ATOM 641 C CD . PRO A 1 80 ? 8.927 -17.176 -23.168 1.00 18.49 ? 80 PRO A CD 1 ATOM 642 N N . LYS A 1 81 ? 4.850 -15.772 -22.094 1.00 19.93 ? 81 LYS A N 1 ATOM 643 C CA . LYS A 1 81 ? 4.162 -15.506 -20.822 1.00 20.06 ? 81 LYS A CA 1 ATOM 644 C C . LYS A 1 81 ? 2.976 -16.459 -20.535 1.00 20.51 ? 81 LYS A C 1 ATOM 645 O O . LYS A 1 81 ? 2.370 -16.411 -19.454 1.00 21.40 ? 81 LYS A O 1 ATOM 646 C CB . LYS A 1 81 ? 3.748 -14.024 -20.815 1.00 20.22 ? 81 LYS A CB 1 ATOM 647 C CG . LYS A 1 81 ? 4.994 -13.096 -20.725 1.00 19.40 ? 81 LYS A CG 1 ATOM 648 C CD . LYS A 1 81 ? 4.739 -11.659 -21.087 1.00 16.03 ? 81 LYS A CD 1 ATOM 649 C CE . LYS A 1 81 ? 4.553 -11.462 -22.585 1.00 16.65 ? 81 LYS A CE 1 ATOM 650 N NZ . LYS A 1 81 ? 5.869 -11.391 -23.327 1.00 16.19 ? 81 LYS A NZ 1 ATOM 651 N N . GLY A 1 82 ? 2.659 -17.338 -21.493 1.00 20.33 ? 82 GLY A N 1 ATOM 652 C CA . GLY A 1 82 ? 1.566 -18.307 -21.339 1.00 19.43 ? 82 GLY A CA 1 ATOM 653 C C . GLY A 1 82 ? 0.237 -17.741 -21.850 1.00 19.27 ? 82 GLY A C 1 ATOM 654 O O . GLY A 1 82 ? 0.071 -17.561 -23.059 1.00 19.66 ? 82 GLY A O 1 ATOM 655 N N . ALA A 1 83 ? -0.670 -17.426 -20.922 1.00 18.30 ? 83 ALA A N 1 ATOM 656 C CA . ALA A 1 83 ? -2.043 -17.004 -21.237 1.00 17.89 ? 83 ALA A CA 1 ATOM 657 C C . ALA A 1 83 ? -2.439 -15.634 -20.613 1.00 17.99 ? 83 ALA A C 1 ATOM 658 O O . ALA A 1 83 ? -1.970 -15.276 -19.517 1.00 17.61 ? 83 ALA A O 1 ATOM 659 C CB . ALA A 1 83 ? -3.029 -18.080 -20.777 1.00 17.32 ? 83 ALA A CB 1 ATOM 660 N N . ALA A 1 84 ? -3.277 -14.881 -21.333 1.00 16.86 ? 84 ALA A N 1 ATOM 661 C CA . ALA A 1 84 ? -3.899 -13.668 -20.798 1.00 17.03 ? 84 ALA A CA 1 ATOM 662 C C . ALA A 1 84 ? -5.336 -13.992 -20.357 1.00 17.00 ? 84 ALA A C 1 ATOM 663 O O . ALA A 1 84 ? -6.207 -14.133 -21.206 1.00 17.63 ? 84 ALA A O 1 ATOM 664 C CB . ALA A 1 84 ? -3.885 -12.564 -21.834 1.00 16.61 ? 84 ALA A CB 1 ATOM 665 N N . LEU A 1 85 ? -5.552 -14.098 -19.041 1.00 16.82 ? 85 LEU A N 1 ATOM 666 C CA . LEU A 1 85 ? -6.819 -14.583 -18.454 1.00 17.94 ? 85 LEU A CA 1 ATOM 667 C C . LEU A 1 85 ? -7.841 -13.495 -17.997 1.00 18.19 ? 85 LEU A C 1 ATOM 668 O O . LEU A 1 85 ? -9.018 -13.807 -17.732 1.00 18.90 ? 85 LEU A O 1 ATOM 669 C CB . LEU A 1 85 ? -6.525 -15.587 -17.309 1.00 16.45 ? 85 LEU A CB 1 ATOM 670 C CG . LEU A 1 85 ? -5.740 -16.865 -17.670 1.00 17.94 ? 85 LEU A CG 1 ATOM 671 C CD1 . LEU A 1 85 ? -5.569 -17.803 -16.438 1.00 14.69 ? 85 LEU A CD1 1 ATOM 672 C CD2 . LEU A 1 85 ? -6.358 -17.646 -18.876 1.00 15.58 ? 85 LEU A CD2 1 ATOM 673 N N . HIS A 1 86 ? -7.419 -12.230 -17.935 1.00 18.42 ? 86 HIS A N 1 ATOM 674 C CA . HIS A 1 86 ? -8.315 -11.124 -17.527 1.00 18.68 ? 86 HIS A CA 1 ATOM 675 C C . HIS A 1 86 ? -8.213 -9.988 -18.543 1.00 18.31 ? 86 HIS A C 1 ATOM 676 O O . HIS A 1 86 ? -7.280 -9.179 -18.483 1.00 18.43 ? 86 HIS A O 1 ATOM 677 C CB . HIS A 1 86 ? -7.961 -10.614 -16.113 1.00 18.82 ? 86 HIS A CB 1 ATOM 678 C CG . HIS A 1 86 ? -8.991 -9.704 -15.521 1.00 19.85 ? 86 HIS A CG 1 ATOM 679 N ND1 . HIS A 1 86 ? -9.682 -10.012 -14.366 1.00 22.52 ? 86 HIS A ND1 1 ATOM 680 C CD2 . HIS A 1 86 ? -9.471 -8.502 -15.935 1.00 23.28 ? 86 HIS A CD2 1 ATOM 681 C CE1 . HIS A 1 86 ? -10.523 -9.034 -14.078 1.00 22.16 ? 86 HIS A CE1 1 ATOM 682 N NE2 . HIS A 1 86 ? -10.427 -8.112 -15.022 1.00 23.61 ? 86 HIS A NE2 1 ATOM 683 N N . LEU A 1 87 ? -9.144 -9.962 -19.494 1.00 18.29 ? 87 LEU A N 1 ATOM 684 C CA . LEU A 1 87 ? -9.159 -8.962 -20.580 1.00 18.65 ? 87 LEU A CA 1 ATOM 685 C C . LEU A 1 87 ? -10.608 -8.662 -20.864 1.00 19.25 ? 87 LEU A C 1 ATOM 686 O O . LEU A 1 87 ? -11.438 -9.525 -20.685 1.00 19.17 ? 87 LEU A O 1 ATOM 687 C CB . LEU A 1 87 ? -8.549 -9.530 -21.885 1.00 17.72 ? 87 LEU A CB 1 ATOM 688 C CG . LEU A 1 87 ? -7.112 -10.093 -21.883 1.00 17.27 ? 87 LEU A CG 1 ATOM 689 C CD1 . LEU A 1 87 ? -6.889 -10.813 -23.220 1.00 16.37 ? 87 LEU A CD1 1 ATOM 690 C CD2 . LEU A 1 87 ? -6.145 -8.933 -21.774 1.00 16.03 ? 87 LEU A CD2 1 ATOM 691 N N . HIS A 1 88 ? -10.891 -7.446 -21.309 1.00 20.03 ? 88 HIS A N 1 ATOM 692 C CA . HIS A 1 88 ? -12.239 -7.031 -21.739 1.00 21.72 ? 88 HIS A CA 1 ATOM 693 C C . HIS A 1 88 ? -12.294 -6.856 -23.241 1.00 21.69 ? 88 HIS A C 1 ATOM 694 O O . HIS A 1 88 ? -11.303 -6.447 -23.844 1.00 22.36 ? 88 HIS A O 1 ATOM 695 C CB . HIS A 1 88 ? -12.644 -5.725 -21.054 1.00 21.78 ? 88 HIS A CB 1 ATOM 696 C CG . HIS A 1 88 ? -12.722 -5.850 -19.568 1.00 25.03 ? 88 HIS A CG 1 ATOM 697 N ND1 . HIS A 1 88 ? -13.894 -6.155 -18.906 1.00 26.40 ? 88 HIS A ND1 1 ATOM 698 C CD2 . HIS A 1 88 ? -11.764 -5.773 -18.619 1.00 26.03 ? 88 HIS A CD2 1 ATOM 699 C CE1 . HIS A 1 88 ? -13.659 -6.223 -17.609 1.00 26.75 ? 88 HIS A CE1 1 ATOM 700 N NE2 . HIS A 1 88 ? -12.372 -5.999 -17.409 1.00 26.95 ? 88 HIS A NE2 1 ATOM 701 N N . ASP A 1 89 ? -13.465 -7.140 -23.808 1.00 22.15 ? 89 ASP A N 1 ATOM 702 C CA . ASP A 1 89 ? -13.728 -7.154 -25.256 1.00 23.49 ? 89 ASP A CA 1 ATOM 703 C C . ASP A 1 89 ? -13.220 -5.988 -26.090 1.00 23.67 ? 89 ASP A C 1 ATOM 704 O O . ASP A 1 89 ? -12.741 -6.206 -27.203 1.00 24.68 ? 89 ASP A O 1 ATOM 705 C CB . ASP A 1 89 ? -15.224 -7.401 -25.565 1.00 23.37 ? 89 ASP A CB 1 ATOM 706 C CG . ASP A 1 89 ? -16.177 -6.432 -24.799 1.00 28.17 ? 89 ASP A CG 1 ATOM 707 O OD1 . ASP A 1 89 ? -15.716 -5.505 -24.105 1.00 33.07 ? 89 ASP A OD1 1 ATOM 708 O OD2 . ASP A 1 89 ? -17.420 -6.601 -24.889 1.00 33.06 ? 89 ASP A OD2 1 ATOM 709 N N . ILE A 1 90 ? -13.326 -4.758 -25.596 1.00 22.81 ? 90 ILE A N 1 ATOM 710 C CA . ILE A 1 90 ? -13.005 -3.620 -26.464 1.00 22.97 ? 90 ILE A CA 1 ATOM 711 C C . ILE A 1 90 ? -11.813 -2.773 -26.012 1.00 22.89 ? 90 ILE A C 1 ATOM 712 O O . ILE A 1 90 ? -11.638 -1.646 -26.486 1.00 22.51 ? 90 ILE A O 1 ATOM 713 C CB . ILE A 1 90 ? -14.231 -2.711 -26.786 1.00 22.88 ? 90 ILE A CB 1 ATOM 714 C CG1 . ILE A 1 90 ? -14.789 -2.075 -25.523 1.00 24.37 ? 90 ILE A CG1 1 ATOM 715 C CG2 . ILE A 1 90 ? -15.333 -3.483 -27.579 1.00 21.52 ? 90 ILE A CG2 1 ATOM 716 C CD1 . ILE A 1 90 ? -15.968 -1.178 -25.808 1.00 24.92 ? 90 ILE A CD1 1 ATOM 717 N N . GLY A 1 91 ? -10.975 -3.336 -25.148 1.00 22.81 ? 91 GLY A N 1 ATOM 718 C CA . GLY A 1 91 ? -9.775 -2.636 -24.699 1.00 22.52 ? 91 GLY A CA 1 ATOM 719 C C . GLY A 1 91 ? -8.458 -3.307 -25.045 1.00 22.79 ? 91 GLY A C 1 ATOM 720 O O . GLY A 1 91 ? -7.436 -3.042 -24.399 1.00 22.51 ? 91 GLY A O 1 ATOM 721 N N . ILE A 1 92 ? -8.466 -4.175 -26.055 1.00 22.27 ? 92 ILE A N 1 ATOM 722 C CA . ILE A 1 92 ? -7.336 -5.092 -26.279 1.00 22.38 ? 92 ILE A CA 1 ATOM 723 C C . ILE A 1 92 ? -6.638 -4.906 -27.630 1.00 22.94 ? 92 ILE A C 1 ATOM 724 O O . ILE A 1 92 ? -5.833 -5.766 -28.037 1.00 23.65 ? 92 ILE A O 1 ATOM 725 C CB . ILE A 1 92 ? -7.771 -6.583 -26.110 1.00 22.30 ? 92 ILE A CB 1 ATOM 726 C CG1 . ILE A 1 92 ? -9.008 -6.894 -26.978 1.00 20.84 ? 92 ILE A CG1 1 ATOM 727 C CG2 . ILE A 1 92 ? -8.021 -6.903 -24.624 1.00 22.67 ? 92 ILE A CG2 1 ATOM 728 C CD1 . ILE A 1 92 ? -9.516 -8.333 -26.884 1.00 18.47 ? 92 ILE A CD1 1 ATOM 729 N N . VAL A 1 93 ? -6.966 -3.810 -28.331 1.00 22.70 ? 93 VAL A N 1 ATOM 730 C CA . VAL A 1 93 ? -6.346 -3.493 -29.627 1.00 22.07 ? 93 VAL A CA 1 ATOM 731 C C . VAL A 1 93 ? -5.886 -2.042 -29.597 1.00 22.18 ? 93 VAL A C 1 ATOM 732 O O . VAL A 1 93 ? -6.680 -1.138 -29.309 1.00 20.51 ? 93 VAL A O 1 ATOM 733 C CB . VAL A 1 93 ? -7.309 -3.716 -30.849 1.00 22.32 ? 93 VAL A CB 1 ATOM 734 C CG1 . VAL A 1 93 ? -6.662 -3.243 -32.187 1.00 22.21 ? 93 VAL A CG1 1 ATOM 735 C CG2 . VAL A 1 93 ? -7.766 -5.174 -30.968 1.00 22.20 ? 93 VAL A CG2 1 ATOM 736 N N . THR A 1 94 ? -4.602 -1.831 -29.884 1.00 22.91 ? 94 THR A N 1 ATOM 737 C CA . THR A 1 94 ? -4.023 -0.488 -29.932 1.00 24.40 ? 94 THR A CA 1 ATOM 738 C C . THR A 1 94 ? -4.917 0.492 -30.693 1.00 25.07 ? 94 THR A C 1 ATOM 739 O O . THR A 1 94 ? -5.389 0.193 -31.790 1.00 25.28 ? 94 THR A O 1 ATOM 740 C CB . THR A 1 94 ? -2.591 -0.535 -30.506 1.00 24.71 ? 94 THR A CB 1 ATOM 741 O OG1 . THR A 1 94 ? -1.808 -1.390 -29.671 1.00 26.02 ? 94 THR A OG1 1 ATOM 742 C CG2 . THR A 1 94 ? -1.934 0.853 -30.501 1.00 25.73 ? 94 THR A CG2 1 ATOM 743 N N . MET A 1 95 ? -5.175 1.649 -30.093 1.00 25.69 ? 95 MET A N 1 ATOM 744 C CA . MET A 1 95 ? -6.204 2.566 -30.615 1.00 26.10 ? 95 MET A CA 1 ATOM 745 C C . MET A 1 95 ? -5.833 3.259 -31.935 1.00 26.99 ? 95 MET A C 1 ATOM 746 O O . MET A 1 95 ? -6.725 3.698 -32.674 1.00 25.80 ? 95 MET A O 1 ATOM 747 C CB . MET A 1 95 ? -6.642 3.573 -29.553 1.00 25.70 ? 95 MET A CB 1 ATOM 748 C CG . MET A 1 95 ? -7.264 2.924 -28.334 1.00 27.05 ? 95 MET A CG 1 ATOM 749 S SD . MET A 1 95 ? -8.867 2.152 -28.715 1.00 30.26 ? 95 MET A SD 1 ATOM 750 C CE . MET A 1 95 ? -9.421 1.822 -27.044 1.00 27.83 ? 95 MET A CE 1 ATOM 751 N N . ASP A 1 96 ? -4.526 3.332 -32.211 1.00 27.19 ? 96 ASP A N 1 ATOM 752 C CA . ASP A 1 96 ? -3.967 3.862 -33.445 1.00 29.06 ? 96 ASP A CA 1 ATOM 753 C C . ASP A 1 96 ? -4.675 3.289 -34.685 1.00 28.88 ? 96 ASP A C 1 ATOM 754 O O . ASP A 1 96 ? -5.063 4.038 -35.583 1.00 28.34 ? 96 ASP A O 1 ATOM 755 C CB . ASP A 1 96 ? -2.476 3.509 -33.529 1.00 30.12 ? 96 ASP A CB 1 ATOM 756 C CG . ASP A 1 96 ? -1.589 4.724 -33.704 1.00 35.70 ? 96 ASP A CG 1 ATOM 757 O OD1 . ASP A 1 96 ? -1.222 5.045 -34.866 1.00 41.64 ? 96 ASP A OD1 1 ATOM 758 O OD2 . ASP A 1 96 ? -1.238 5.360 -32.671 1.00 40.48 ? 96 ASP A OD2 1 ATOM 759 N N . TRP A 1 97 ? -4.828 1.963 -34.711 1.00 28.94 ? 97 TRP A N 1 ATOM 760 C CA . TRP A 1 97 ? -5.496 1.248 -35.801 1.00 28.84 ? 97 TRP A CA 1 ATOM 761 C C . TRP A 1 97 ? -6.979 1.624 -35.917 1.00 28.38 ? 97 TRP A C 1 ATOM 762 O O . TRP A 1 97 ? -7.521 1.676 -37.021 1.00 28.21 ? 97 TRP A O 1 ATOM 763 C CB . TRP A 1 97 ? -5.353 -0.258 -35.599 1.00 28.87 ? 97 TRP A CB 1 ATOM 764 C CG . TRP A 1 97 ? -6.043 -1.116 -36.646 1.00 28.86 ? 97 TRP A CG 1 ATOM 765 C CD1 . TRP A 1 97 ? -5.562 -1.434 -37.889 1.00 30.10 ? 97 TRP A CD1 1 ATOM 766 C CD2 . TRP A 1 97 ? -7.305 -1.787 -36.523 1.00 28.48 ? 97 TRP A CD2 1 ATOM 767 N NE1 . TRP A 1 97 ? -6.448 -2.244 -38.548 1.00 29.36 ? 97 TRP A NE1 1 ATOM 768 C CE2 . TRP A 1 97 ? -7.528 -2.479 -37.738 1.00 28.43 ? 97 TRP A CE2 1 ATOM 769 C CE3 . TRP A 1 97 ? -8.275 -1.868 -35.509 1.00 26.82 ? 97 TRP A CE3 1 ATOM 770 C CZ2 . TRP A 1 97 ? -8.681 -3.236 -37.971 1.00 27.74 ? 97 TRP A CZ2 1 ATOM 771 C CZ3 . TRP A 1 97 ? -9.417 -2.629 -35.739 1.00 24.66 ? 97 TRP A CZ3 1 ATOM 772 C CH2 . TRP A 1 97 ? -9.609 -3.303 -36.964 1.00 26.65 ? 97 TRP A CH2 1 ATOM 773 N N . LEU A 1 98 ? -7.638 1.883 -34.789 1.00 28.11 ? 98 LEU A N 1 ATOM 774 C CA . LEU A 1 98 ? -9.029 2.342 -34.836 1.00 28.31 ? 98 LEU A CA 1 ATOM 775 C C . LEU A 1 98 ? -9.112 3.653 -35.602 1.00 28.63 ? 98 LEU A C 1 ATOM 776 O O . LEU A 1 98 ? -10.018 3.845 -36.412 1.00 28.58 ? 98 LEU A O 1 ATOM 777 C CB . LEU A 1 98 ? -9.629 2.534 -33.434 1.00 28.05 ? 98 LEU A CB 1 ATOM 778 C CG . LEU A 1 98 ? -10.402 1.426 -32.708 1.00 28.35 ? 98 LEU A CG 1 ATOM 779 C CD1 . LEU A 1 98 ? -11.167 2.028 -31.537 1.00 27.61 ? 98 LEU A CD1 1 ATOM 780 C CD2 . LEU A 1 98 ? -11.356 0.618 -33.615 1.00 26.22 ? 98 LEU A CD2 1 ATOM 781 N N . VAL A 1 99 ? -8.162 4.553 -35.341 1.00 28.91 ? 99 VAL A N 1 ATOM 782 C CA . VAL A 1 99 ? -8.147 5.866 -35.988 1.00 29.75 ? 99 VAL A CA 1 ATOM 783 C C . VAL A 1 99 ? -7.667 5.800 -37.451 1.00 30.64 ? 99 VAL A C 1 ATOM 784 O O . VAL A 1 99 ? -8.399 6.192 -38.367 1.00 30.53 ? 99 VAL A O 1 ATOM 785 C CB . VAL A 1 99 ? -7.321 6.931 -35.178 1.00 29.78 ? 99 VAL A CB 1 ATOM 786 C CG1 . VAL A 1 99 ? -7.239 8.242 -35.955 1.00 30.11 ? 99 VAL A CG1 1 ATOM 787 C CG2 . VAL A 1 99 ? -7.956 7.205 -33.828 1.00 28.31 ? 99 VAL A CG2 1 ATOM 788 N N . ARG A 1 100 ? -6.455 5.297 -37.654 1.00 31.26 ? 100 ARG A N 1 ATOM 789 C CA . ARG A 1 100 ? -5.769 5.394 -38.954 1.00 33.18 ? 100 ARG A CA 1 ATOM 790 C C . ARG A 1 100 ? -6.380 4.483 -40.015 1.00 32.96 ? 100 ARG A C 1 ATOM 791 O O . ARG A 1 100 ? -6.400 4.815 -41.194 1.00 32.56 ? 100 ARG A O 1 ATOM 792 C CB . ARG A 1 100 ? -4.278 5.084 -38.799 1.00 33.26 ? 100 ARG A CB 1 ATOM 793 C CG . ARG A 1 100 ? -3.425 6.312 -38.487 1.00 37.75 ? 100 ARG A CG 1 ATOM 794 C CD . ARG A 1 100 ? -2.668 6.825 -39.736 1.00 44.07 ? 100 ARG A CD 1 ATOM 795 N NE . ARG A 1 100 ? -3.486 7.633 -40.657 1.00 48.00 ? 100 ARG A NE 1 ATOM 796 C CZ . ARG A 1 100 ? -4.044 7.185 -41.786 1.00 50.04 ? 100 ARG A CZ 1 ATOM 797 N NH1 . ARG A 1 100 ? -3.903 5.920 -42.173 1.00 51.04 ? 100 ARG A NH1 1 ATOM 798 N NH2 . ARG A 1 100 ? -4.750 8.013 -42.539 1.00 52.44 ? 100 ARG A NH2 1 ATOM 799 N N . ASN A 1 101 ? -6.883 3.337 -39.573 1.00 33.21 ? 101 ASN A N 1 ATOM 800 C CA . ASN A 1 101 ? -7.485 2.367 -40.461 1.00 33.31 ? 101 ASN A CA 1 ATOM 801 C C . ASN A 1 101 ? -9.033 2.463 -40.421 1.00 32.40 ? 101 ASN A C 1 ATOM 802 O O . ASN A 1 101 ? -9.665 2.788 -41.432 1.00 31.38 ? 101 ASN A O 1 ATOM 803 C CB . ASN A 1 101 ? -6.931 0.985 -40.104 1.00 34.02 ? 101 ASN A CB 1 ATOM 804 C CG . ASN A 1 101 ? -7.474 -0.124 -40.977 1.00 37.38 ? 101 ASN A CG 1 ATOM 805 O OD1 . ASN A 1 101 ? -8.691 -0.361 -41.028 1.00 36.93 ? 101 ASN A OD1 1 ATOM 806 N ND2 . ASN A 1 101 ? -6.564 -0.831 -41.657 1.00 41.12 ? 101 ASN A ND2 1 ATOM 807 N N . VAL A 1 102 ? -9.635 2.256 -39.252 1.00 31.06 ? 102 VAL A N 1 ATOM 808 C CA . VAL A 1 102 ? -11.090 2.081 -39.180 1.00 29.85 ? 102 VAL A CA 1 ATOM 809 C C . VAL A 1 102 ? -11.924 3.330 -39.550 1.00 29.69 ? 102 VAL A C 1 ATOM 810 O O . VAL A 1 102 ? -12.904 3.210 -40.294 1.00 28.51 ? 102 VAL A O 1 ATOM 811 C CB . VAL A 1 102 ? -11.534 1.411 -37.842 1.00 29.64 ? 102 VAL A CB 1 ATOM 812 C CG1 . VAL A 1 102 ? -13.069 1.405 -37.684 1.00 28.89 ? 102 VAL A CG1 1 ATOM 813 C CG2 . VAL A 1 102 ? -10.971 -0.014 -37.760 1.00 28.24 ? 102 VAL A CG2 1 ATOM 814 N N . THR A 1 103 ? -11.535 4.510 -39.066 1.00 29.33 ? 103 THR A N 1 ATOM 815 C CA . THR A 1 103 ? -12.302 5.739 -39.366 1.00 29.93 ? 103 THR A CA 1 ATOM 816 C C . THR A 1 103 ? -12.081 6.237 -40.814 1.00 30.06 ? 103 THR A C 1 ATOM 817 O O . THR A 1 103 ? -12.729 7.177 -41.266 1.00 29.44 ? 103 THR A O 1 ATOM 818 C CB . THR A 1 103 ? -12.046 6.911 -38.356 1.00 30.06 ? 103 THR A CB 1 ATOM 819 O OG1 . THR A 1 103 ? -10.698 7.389 -38.477 1.00 28.30 ? 103 THR A OG1 1 ATOM 820 C CG2 . THR A 1 103 ? -12.337 6.472 -36.882 1.00 30.20 ? 103 THR A CG2 1 ATOM 821 N N . TYR A 1 104 ? -11.158 5.595 -41.515 1.00 30.75 ? 104 TYR A N 1 ATOM 822 C CA . TYR A 1 104 ? -10.907 5.871 -42.932 1.00 31.01 ? 104 TYR A CA 1 ATOM 823 C C . TYR A 1 104 ? -11.670 4.922 -43.861 1.00 30.94 ? 104 TYR A C 1 ATOM 824 O O . TYR A 1 104 ? -11.572 5.028 -45.087 1.00 30.97 ? 104 TYR A O 1 ATOM 825 C CB . TYR A 1 104 ? -9.402 5.835 -43.214 1.00 30.81 ? 104 TYR A CB 1 ATOM 826 C CG . TYR A 1 104 ? -8.735 7.166 -42.933 1.00 32.44 ? 104 TYR A CG 1 ATOM 827 C CD1 . TYR A 1 104 ? -8.194 7.448 -41.670 1.00 32.50 ? 104 TYR A CD1 1 ATOM 828 C CD2 . TYR A 1 104 ? -8.674 8.160 -43.920 1.00 33.23 ? 104 TYR A CD2 1 ATOM 829 C CE1 . TYR A 1 104 ? -7.588 8.667 -41.404 1.00 32.30 ? 104 TYR A CE1 1 ATOM 830 C CE2 . TYR A 1 104 ? -8.078 9.385 -43.665 1.00 32.81 ? 104 TYR A CE2 1 ATOM 831 C CZ . TYR A 1 104 ? -7.533 9.632 -42.407 1.00 33.47 ? 104 TYR A CZ 1 ATOM 832 O OH . TYR A 1 104 ? -6.948 10.844 -42.149 1.00 33.47 ? 104 TYR A OH 1 ATOM 833 N N . ARG A 1 105 ? -12.429 3.995 -43.276 1.00 30.90 ? 105 ARG A N 1 ATOM 834 C CA . ARG A 1 105 ? -13.211 3.024 -44.048 1.00 30.47 ? 105 ARG A CA 1 ATOM 835 C C . ARG A 1 105 ? -14.478 3.651 -44.623 1.00 30.84 ? 105 ARG A C 1 ATOM 836 O O . ARG A 1 105 ? -15.017 4.612 -44.055 1.00 30.26 ? 105 ARG A O 1 ATOM 837 C CB . ARG A 1 105 ? -13.564 1.802 -43.195 1.00 30.73 ? 105 ARG A CB 1 ATOM 838 C CG . ARG A 1 105 ? -12.392 0.873 -42.963 1.00 29.44 ? 105 ARG A CG 1 ATOM 839 C CD . ARG A 1 105 ? -12.755 -0.244 -42.004 1.00 32.08 ? 105 ARG A CD 1 ATOM 840 N NE . ARG A 1 105 ? -11.594 -1.072 -41.666 1.00 32.39 ? 105 ARG A NE 1 ATOM 841 C CZ . ARG A 1 105 ? -11.632 -2.388 -41.460 1.00 33.53 ? 105 ARG A CZ 1 ATOM 842 N NH1 . ARG A 1 105 ? -12.765 -3.076 -41.579 1.00 33.22 ? 105 ARG A NH1 1 ATOM 843 N NH2 . ARG A 1 105 ? -10.521 -3.022 -41.139 1.00 35.09 ? 105 ARG A NH2 1 ATOM 844 N N . PRO A 1 106 ? -14.959 3.116 -45.770 1.00 31.11 ? 106 PRO A N 1 ATOM 845 C CA . PRO A 1 106 ? -16.184 3.654 -46.384 1.00 30.70 ? 106 PRO A CA 1 ATOM 846 C C . PRO A 1 106 ? -17.374 3.683 -45.419 1.00 30.34 ? 106 PRO A C 1 ATOM 847 O O . PRO A 1 106 ? -17.535 2.766 -44.616 1.00 30.85 ? 106 PRO A O 1 ATOM 848 C CB . PRO A 1 106 ? -16.456 2.677 -47.536 1.00 30.80 ? 106 PRO A CB 1 ATOM 849 C CG . PRO A 1 106 ? -15.103 2.128 -47.906 1.00 31.38 ? 106 PRO A CG 1 ATOM 850 C CD . PRO A 1 106 ? -14.338 2.052 -46.594 1.00 31.08 ? 106 PRO A CD 1 ATOM 851 N N . HIS A 1 107 ? -18.182 4.740 -45.495 1.00 29.80 ? 107 HIS A N 1 ATOM 852 C CA . HIS A 1 107 ? -19.452 4.887 -44.755 1.00 29.86 ? 107 HIS A CA 1 ATOM 853 C C . HIS A 1 107 ? -19.295 5.221 -43.261 1.00 29.21 ? 107 HIS A C 1 ATOM 854 O O . HIS A 1 107 ? -20.275 5.217 -42.509 1.00 28.64 ? 107 HIS A O 1 ATOM 855 C CB . HIS A 1 107 ? -20.375 3.660 -44.932 1.00 30.74 ? 107 HIS A CB 1 ATOM 856 C CG . HIS A 1 107 ? -20.460 3.158 -46.346 1.00 33.66 ? 107 HIS A CG 1 ATOM 857 N ND1 . HIS A 1 107 ? -21.140 3.836 -47.338 1.00 36.25 ? 107 HIS A ND1 1 ATOM 858 C CD2 . HIS A 1 107 ? -19.966 2.039 -46.928 1.00 34.78 ? 107 HIS A CD2 1 ATOM 859 C CE1 . HIS A 1 107 ? -21.054 3.159 -48.471 1.00 37.02 ? 107 HIS A CE1 1 ATOM 860 N NE2 . HIS A 1 107 ? -20.338 2.071 -48.252 1.00 35.89 ? 107 HIS A NE2 1 ATOM 861 N N . CYS A 1 108 ? -18.075 5.529 -42.830 1.00 29.40 ? 108 CYS A N 1 ATOM 862 C CA . CYS A 1 108 ? -17.866 5.968 -41.434 1.00 29.24 ? 108 CYS A CA 1 ATOM 863 C C . CYS A 1 108 ? -18.399 7.379 -41.165 1.00 28.89 ? 108 CYS A C 1 ATOM 864 O O . CYS A 1 108 ? -18.006 8.332 -41.831 1.00 28.91 ? 108 CYS A O 1 ATOM 865 C CB . CYS A 1 108 ? -16.391 5.870 -41.056 1.00 29.41 ? 108 CYS A CB 1 ATOM 866 S SG . CYS A 1 108 ? -16.152 5.835 -39.257 1.00 30.98 ? 108 CYS A SG 1 ATOM 867 N N . HIS A 1 109 ? -19.304 7.505 -40.199 1.00 28.93 ? 109 HIS A N 1 ATOM 868 C CA . HIS A 1 109 ? -19.831 8.804 -39.779 1.00 29.29 ? 109 HIS A CA 1 ATOM 869 C C . HIS A 1 109 ? -19.392 9.133 -38.352 1.00 30.33 ? 109 HIS A C 1 ATOM 870 O O . HIS A 1 109 ? -19.174 8.223 -37.522 1.00 29.91 ? 109 HIS A O 1 ATOM 871 C CB . HIS A 1 109 ? -21.360 8.827 -39.838 1.00 29.06 ? 109 HIS A CB 1 ATOM 872 C CG . HIS A 1 109 ? -21.918 8.693 -41.221 1.00 30.20 ? 109 HIS A CG 1 ATOM 873 N ND1 . HIS A 1 109 ? -21.942 7.494 -41.903 1.00 29.26 ? 109 HIS A ND1 1 ATOM 874 C CD2 . HIS A 1 109 ? -22.485 9.609 -42.045 1.00 29.67 ? 109 HIS A CD2 1 ATOM 875 C CE1 . HIS A 1 109 ? -22.491 7.683 -43.093 1.00 30.91 ? 109 HIS A CE1 1 ATOM 876 N NE2 . HIS A 1 109 ? -22.824 8.957 -43.205 1.00 28.93 ? 109 HIS A NE2 1 ATOM 877 N N . ILE A 1 110 ? -19.261 10.432 -38.086 1.00 31.49 ? 110 ILE A N 1 ATOM 878 C CA . ILE A 1 110 ? -18.969 10.969 -36.747 1.00 32.52 ? 110 ILE A CA 1 ATOM 879 C C . ILE A 1 110 ? -20.101 11.905 -36.332 1.00 33.93 ? 110 ILE A C 1 ATOM 880 O O . ILE A 1 110 ? -20.736 12.546 -37.183 1.00 33.27 ? 110 ILE A O 1 ATOM 881 C CB . ILE A 1 110 ? -17.604 11.720 -36.706 1.00 32.42 ? 110 ILE A CB 1 ATOM 882 C CG1 . ILE A 1 110 ? -17.126 11.964 -35.250 1.00 31.48 ? 110 ILE A CG1 1 ATOM 883 C CG2 . ILE A 1 110 ? -17.664 13.033 -37.528 1.00 32.08 ? 110 ILE A CG2 1 ATOM 884 C CD1 . ILE A 1 110 ? -15.733 12.587 -35.141 1.00 27.12 ? 110 ILE A CD1 1 ATOM 885 N N . CYS A 1 111 ? -20.352 11.963 -35.030 1.00 35.52 ? 111 CYS A N 1 ATOM 886 C CA . CYS A 1 111 ? -21.322 12.879 -34.442 1.00 37.78 ? 111 CYS A CA 1 ATOM 887 C C . CYS A 1 111 ? -20.848 13.304 -33.045 1.00 38.29 ? 111 CYS A C 1 ATOM 888 O O . CYS A 1 111 ? -19.946 12.681 -32.479 1.00 37.50 ? 111 CYS A O 1 ATOM 889 C CB . CYS A 1 111 ? -22.681 12.191 -34.344 1.00 38.13 ? 111 CYS A CB 1 ATOM 890 S SG . CYS A 1 111 ? -23.990 13.174 -33.573 1.00 43.26 ? 111 CYS A SG 1 ATOM 891 N N . PHE A 1 112 ? -21.454 14.370 -32.512 1.00 39.66 ? 112 PHE A N 1 ATOM 892 C CA . PHE A 1 112 ? -21.262 14.806 -31.122 1.00 41.06 ? 112 PHE A CA 1 ATOM 893 C C . PHE A 1 112 ? -22.622 15.012 -30.453 1.00 42.22 ? 112 PHE A C 1 ATOM 894 O O . PHE A 1 112 ? -23.479 15.730 -30.975 1.00 42.72 ? 112 PHE A O 1 ATOM 895 C CB . PHE A 1 112 ? -20.442 16.104 -31.046 1.00 40.61 ? 112 PHE A CB 1 ATOM 896 C CG . PHE A 1 112 ? -19.052 15.988 -31.605 1.00 40.73 ? 112 PHE A CG 1 ATOM 897 C CD1 . PHE A 1 112 ? -17.970 15.689 -30.771 1.00 41.03 ? 112 PHE A CD1 1 ATOM 898 C CD2 . PHE A 1 112 ? -18.809 16.204 -32.959 1.00 40.19 ? 112 PHE A CD2 1 ATOM 899 C CE1 . PHE A 1 112 ? -16.666 15.580 -31.290 1.00 40.31 ? 112 PHE A CE1 1 ATOM 900 C CE2 . PHE A 1 112 ? -17.517 16.106 -33.486 1.00 40.64 ? 112 PHE A CE2 1 ATOM 901 C CZ . PHE A 1 112 ? -16.439 15.792 -32.645 1.00 40.97 ? 112 PHE A CZ 1 ATOM 902 N N . THR A 1 113 ? -22.813 14.374 -29.299 1.00 43.58 ? 113 THR A N 1 ATOM 903 C CA . THR A 1 113 ? -24.053 14.478 -28.503 1.00 45.12 ? 113 THR A CA 1 ATOM 904 C C . THR A 1 113 ? -24.351 15.927 -28.044 1.00 45.46 ? 113 THR A C 1 ATOM 905 O O . THR A 1 113 ? -23.479 16.795 -28.139 1.00 45.70 ? 113 THR A O 1 ATOM 906 C CB . THR A 1 113 ? -23.968 13.550 -27.257 1.00 45.09 ? 113 THR A CB 1 ATOM 907 O OG1 . THR A 1 113 ? -23.009 12.511 -27.490 1.00 47.63 ? 113 THR A OG1 1 ATOM 908 C CG2 . THR A 1 113 ? -25.295 12.897 -26.979 1.00 45.86 ? 113 THR A CG2 1 ATOM 909 N N . PRO A 1 114 ? -25.592 16.203 -27.578 1.00 46.13 ? 114 PRO A N 1 ATOM 910 C CA . PRO A 1 114 ? -25.868 17.446 -26.845 1.00 46.47 ? 114 PRO A CA 1 ATOM 911 C C . PRO A 1 114 ? -24.829 17.777 -25.758 1.00 46.89 ? 114 PRO A C 1 ATOM 912 O O . PRO A 1 114 ? -24.390 18.929 -25.675 1.00 47.48 ? 114 PRO A O 1 ATOM 913 C CB . PRO A 1 114 ? -27.239 17.180 -26.225 1.00 46.49 ? 114 PRO A CB 1 ATOM 914 C CG . PRO A 1 114 ? -27.922 16.283 -27.220 1.00 46.33 ? 114 PRO A CG 1 ATOM 915 C CD . PRO A 1 114 ? -26.847 15.542 -27.995 1.00 46.20 ? 114 PRO A CD 1 ATOM 916 N N . ARG A 1 115 ? -24.422 16.786 -24.958 1.00 46.83 ? 115 ARG A N 1 ATOM 917 C CA . ARG A 1 115 ? -23.356 16.990 -23.970 1.00 46.61 ? 115 ARG A CA 1 ATOM 918 C C . ARG A 1 115 ? -21.982 17.216 -24.617 1.00 45.63 ? 115 ARG A C 1 ATOM 919 O O . ARG A 1 115 ? -21.076 17.745 -23.975 1.00 45.89 ? 115 ARG A O 1 ATOM 920 C CB . ARG A 1 115 ? -23.279 15.823 -22.970 1.00 47.47 ? 115 ARG A CB 1 ATOM 921 C CG . ARG A 1 115 ? -22.479 16.137 -21.678 1.00 49.42 ? 115 ARG A CG 1 ATOM 922 C CD . ARG A 1 115 ? -21.896 14.887 -21.008 1.00 52.14 ? 115 ARG A CD 1 ATOM 923 N NE . ARG A 1 115 ? -22.798 14.294 -20.020 1.00 55.94 ? 115 ARG A NE 1 ATOM 924 C CZ . ARG A 1 115 ? -23.665 13.307 -20.263 1.00 57.76 ? 115 ARG A CZ 1 ATOM 925 N NH1 . ARG A 1 115 ? -23.764 12.775 -21.477 1.00 58.24 ? 115 ARG A NH1 1 ATOM 926 N NH2 . ARG A 1 115 ? -24.442 12.845 -19.283 1.00 58.02 ? 115 ARG A NH2 1 ATOM 927 N N . GLY A 1 116 ? -21.828 16.822 -25.880 1.00 44.56 ? 116 GLY A N 1 ATOM 928 C CA . GLY A 1 116 ? -20.564 17.000 -26.603 1.00 42.75 ? 116 GLY A CA 1 ATOM 929 C C . GLY A 1 116 ? -19.700 15.749 -26.702 1.00 41.78 ? 116 GLY A C 1 ATOM 930 O O . GLY A 1 116 ? -18.507 15.837 -26.982 1.00 41.77 ? 116 GLY A O 1 ATOM 931 N N . ILE A 1 117 ? -20.306 14.582 -26.495 1.00 40.30 ? 117 ILE A N 1 ATOM 932 C CA . ILE A 1 117 ? -19.564 13.320 -26.530 1.00 39.10 ? 117 ILE A CA 1 ATOM 933 C C . ILE A 1 117 ? -19.484 12.753 -27.952 1.00 37.63 ? 117 ILE A C 1 ATOM 934 O O . ILE A 1 117 ? -20.503 12.559 -28.617 1.00 37.84 ? 117 ILE A O 1 ATOM 935 C CB . ILE A 1 117 ? -20.168 12.274 -25.542 1.00 39.38 ? 117 ILE A CB 1 ATOM 936 C CG1 . ILE A 1 117 ? -20.196 12.836 -24.107 1.00 39.82 ? 117 ILE A CG1 1 ATOM 937 C CG2 . ILE A 1 117 ? -19.403 10.935 -25.608 1.00 39.01 ? 117 ILE A CG2 1 ATOM 938 C CD1 . ILE A 1 117 ? -21.019 11.991 -23.136 1.00 41.19 ? 117 ILE A CD1 1 ATOM 939 N N . MET A 1 118 ? -18.266 12.492 -28.406 1.00 35.62 ? 118 MET A N 1 ATOM 940 C CA . MET A 1 118 ? -18.032 11.890 -29.712 1.00 34.09 ? 118 MET A CA 1 ATOM 941 C C . MET A 1 118 ? -18.667 10.490 -29.815 1.00 32.80 ? 118 MET A C 1 ATOM 942 O O . MET A 1 118 ? -18.645 9.693 -28.859 1.00 31.29 ? 118 MET A O 1 ATOM 943 C CB . MET A 1 118 ? -16.530 11.817 -29.954 1.00 34.63 ? 118 MET A CB 1 ATOM 944 C CG . MET A 1 118 ? -16.061 11.476 -31.345 1.00 35.36 ? 118 MET A CG 1 ATOM 945 S SD . MET A 1 118 ? -14.262 11.681 -31.411 1.00 40.55 ? 118 MET A SD 1 ATOM 946 C CE . MET A 1 118 ? -13.678 10.150 -30.759 1.00 40.02 ? 118 MET A CE 1 ATOM 947 N N . GLN A 1 119 ? -19.249 10.215 -30.982 1.00 31.08 ? 119 GLN A N 1 ATOM 948 C CA . GLN A 1 119 ? -19.748 8.880 -31.317 1.00 30.26 ? 119 GLN A CA 1 ATOM 949 C C . GLN A 1 119 ? -19.653 8.641 -32.831 1.00 29.40 ? 119 GLN A C 1 ATOM 950 O O . GLN A 1 119 ? -19.505 9.586 -33.620 1.00 29.18 ? 119 GLN A O 1 ATOM 951 C CB . GLN A 1 119 ? -21.176 8.670 -30.788 1.00 30.49 ? 119 GLN A CB 1 ATOM 952 C CG . GLN A 1 119 ? -22.206 9.566 -31.433 1.00 33.25 ? 119 GLN A CG 1 ATOM 953 C CD . GLN A 1 119 ? -23.539 9.564 -30.718 1.00 36.31 ? 119 GLN A CD 1 ATOM 954 O OE1 . GLN A 1 119 ? -24.128 10.658 -30.608 1.00 39.72 ? 119 GLN A OE1 1 ATOM 955 N NE2 . GLN A 1 119 ? -23.994 8.495 -30.262 1.00 37.35 ? 119 GLN A NE2 1 ATOM 956 N N . PHE A 1 120 ? -19.708 7.371 -33.220 1.00 28.72 ? 120 PHE A N 1 ATOM 957 C CA . PHE A 1 120 ? -19.521 6.958 -34.604 1.00 28.13 ? 120 PHE A CA 1 ATOM 958 C C . PHE A 1 120 ? -20.605 5.975 -35.036 1.00 28.14 ? 120 PHE A C 1 ATOM 959 O O . PHE A 1 120 ? -21.177 5.241 -34.202 1.00 27.51 ? 120 PHE A O 1 ATOM 960 C CB . PHE A 1 120 ? -18.152 6.294 -34.807 1.00 27.53 ? 120 PHE A CB 1 ATOM 961 C CG . PHE A 1 120 ? -16.987 7.195 -34.535 1.00 27.69 ? 120 PHE A CG 1 ATOM 962 C CD1 . PHE A 1 120 ? -16.391 7.910 -35.570 1.00 28.47 ? 120 PHE A CD1 1 ATOM 963 C CD2 . PHE A 1 120 ? -16.468 7.321 -33.247 1.00 28.72 ? 120 PHE A CD2 1 ATOM 964 C CE1 . PHE A 1 120 ? -15.290 8.734 -35.336 1.00 27.50 ? 120 PHE A CE1 1 ATOM 965 C CE2 . PHE A 1 120 ? -15.361 8.155 -32.996 1.00 27.46 ? 120 PHE A CE2 1 ATOM 966 C CZ . PHE A 1 120 ? -14.781 8.864 -34.044 1.00 28.16 ? 120 PHE A CZ 1 ATOM 967 N N . ARG A 1 121 ? -20.854 5.956 -36.346 1.00 28.02 ? 121 ARG A N 1 ATOM 968 C CA . ARG A 1 121 ? -21.768 4.998 -36.953 1.00 28.70 ? 121 ARG A CA 1 ATOM 969 C C . ARG A 1 121 ? -21.416 4.752 -38.427 1.00 28.82 ? 121 ARG A C 1 ATOM 970 O O . ARG A 1 121 ? -21.218 5.689 -39.209 1.00 28.45 ? 121 ARG A O 1 ATOM 971 C CB . ARG A 1 121 ? -23.215 5.481 -36.828 1.00 28.98 ? 121 ARG A CB 1 ATOM 972 C CG . ARG A 1 121 ? -24.248 4.409 -37.117 1.00 31.89 ? 121 ARG A CG 1 ATOM 973 C CD . ARG A 1 121 ? -24.972 4.018 -35.858 1.00 39.26 ? 121 ARG A CD 1 ATOM 974 N NE . ARG A 1 121 ? -26.251 4.730 -35.746 1.00 45.49 ? 121 ARG A NE 1 ATOM 975 C CZ . ARG A 1 121 ? -26.773 5.196 -34.611 1.00 48.00 ? 121 ARG A CZ 1 ATOM 976 N NH1 . ARG A 1 121 ? -26.122 5.064 -33.454 1.00 49.58 ? 121 ARG A NH1 1 ATOM 977 N NH2 . ARG A 1 121 ? -27.946 5.821 -34.637 1.00 48.99 ? 121 ARG A NH2 1 ATOM 978 N N . PHE A 1 122 ? -21.320 3.481 -38.793 1.00 28.79 ? 122 PHE A N 1 ATOM 979 C CA . PHE A 1 122 ? -21.204 3.092 -40.180 1.00 28.70 ? 122 PHE A CA 1 ATOM 980 C C . PHE A 1 122 ? -22.625 2.974 -40.710 1.00 29.34 ? 122 PHE A C 1 ATOM 981 O O . PHE A 1 122 ? -23.434 2.277 -40.125 1.00 29.14 ? 122 PHE A O 1 ATOM 982 C CB . PHE A 1 122 ? -20.477 1.763 -40.289 1.00 28.06 ? 122 PHE A CB 1 ATOM 983 C CG . PHE A 1 122 ? -18.985 1.881 -40.181 1.00 27.89 ? 122 PHE A CG 1 ATOM 984 C CD1 . PHE A 1 122 ? -18.341 1.693 -38.953 1.00 25.29 ? 122 PHE A CD1 1 ATOM 985 C CD2 . PHE A 1 122 ? -18.223 2.191 -41.308 1.00 25.84 ? 122 PHE A CD2 1 ATOM 986 C CE1 . PHE A 1 122 ? -16.945 1.786 -38.856 1.00 26.00 ? 122 PHE A CE1 1 ATOM 987 C CE2 . PHE A 1 122 ? -16.822 2.307 -41.226 1.00 26.86 ? 122 PHE A CE2 1 ATOM 988 C CZ . PHE A 1 122 ? -16.179 2.100 -40.000 1.00 26.05 ? 122 PHE A CZ 1 ATOM 989 N N . ALA A 1 123 ? -22.932 3.683 -41.796 1.00 30.59 ? 123 ALA A N 1 ATOM 990 C CA . ALA A 1 123 ? -24.302 3.727 -42.331 1.00 31.65 ? 123 ALA A CA 1 ATOM 991 C C . ALA A 1 123 ? -24.377 4.207 -43.787 1.00 32.79 ? 123 ALA A C 1 ATOM 992 O O . ALA A 1 123 ? -23.493 4.931 -44.258 1.00 32.82 ? 123 ALA A O 1 ATOM 993 C CB . ALA A 1 123 ? -25.217 4.565 -41.439 1.00 31.03 ? 123 ALA A CB 1 ATOM 994 N N . HIS A 1 124 ? -25.414 3.750 -44.491 1.00 33.68 ? 124 HIS A N 1 ATOM 995 C CA . HIS A 1 124 ? -25.749 4.244 -45.825 1.00 35.91 ? 124 HIS A CA 1 ATOM 996 C C . HIS A 1 124 ? -27.267 4.199 -46.019 1.00 36.60 ? 124 HIS A C 1 ATOM 997 O O . HIS A 1 124 ? -27.870 3.159 -45.844 1.00 36.65 ? 124 HIS A O 1 ATOM 998 C CB . HIS A 1 124 ? -25.037 3.460 -46.925 1.00 36.11 ? 124 HIS A CB 1 ATOM 999 C CG . HIS A 1 124 ? -25.178 4.078 -48.283 1.00 38.27 ? 124 HIS A CG 1 ATOM 1000 N ND1 . HIS A 1 124 ? -24.187 4.842 -48.861 1.00 41.05 ? 124 HIS A ND1 1 ATOM 1001 C CD2 . HIS A 1 124 ? -26.201 4.059 -49.169 1.00 39.89 ? 124 HIS A CD2 1 ATOM 1002 C CE1 . HIS A 1 124 ? -24.586 5.258 -50.049 1.00 41.94 ? 124 HIS A CE1 1 ATOM 1003 N NE2 . HIS A 1 124 ? -25.808 4.802 -50.258 1.00 42.30 ? 124 HIS A NE2 1 ATOM 1004 N N . PRO A 1 125 ? -27.902 5.348 -46.314 1.00 37.77 ? 125 PRO A N 1 ATOM 1005 C CA . PRO A 1 125 ? -27.318 6.677 -46.399 1.00 38.37 ? 125 PRO A CA 1 ATOM 1006 C C . PRO A 1 125 ? -27.055 7.268 -45.004 1.00 38.99 ? 125 PRO A C 1 ATOM 1007 O O . PRO A 1 125 ? -27.235 6.589 -43.979 1.00 38.16 ? 125 PRO A O 1 ATOM 1008 C CB . PRO A 1 125 ? -28.412 7.473 -47.127 1.00 38.40 ? 125 PRO A CB 1 ATOM 1009 C CG . PRO A 1 125 ? -29.679 6.863 -46.648 1.00 38.55 ? 125 PRO A CG 1 ATOM 1010 C CD . PRO A 1 125 ? -29.372 5.384 -46.509 1.00 37.93 ? 125 PRO A CD 1 ATOM 1011 N N . THR A 1 126 ? -26.623 8.519 -44.977 1.00 39.95 ? 126 THR A N 1 ATOM 1012 C CA . THR A 1 126 ? -26.445 9.247 -43.728 1.00 41.62 ? 126 THR A CA 1 ATOM 1013 C C . THR A 1 126 ? -27.657 9.049 -42.824 1.00 43.14 ? 126 THR A C 1 ATOM 1014 O O . THR A 1 126 ? -28.791 9.267 -43.253 1.00 43.53 ? 126 THR A O 1 ATOM 1015 C CB . THR A 1 126 ? -26.158 10.745 -44.002 1.00 41.25 ? 126 THR A CB 1 ATOM 1016 O OG1 . THR A 1 126 ? -24.917 10.840 -44.712 1.00 41.47 ? 126 THR A OG1 1 ATOM 1017 C CG2 . THR A 1 126 ? -26.041 11.545 -42.701 1.00 40.11 ? 126 THR A CG2 1 ATOM 1018 N N . PRO A 1 127 ? -27.429 8.579 -41.581 1.00 44.58 ? 127 PRO A N 1 ATOM 1019 C CA . PRO A 1 127 ? -28.560 8.370 -40.680 1.00 45.89 ? 127 PRO A CA 1 ATOM 1020 C C . PRO A 1 127 ? -29.287 9.687 -40.395 1.00 47.42 ? 127 PRO A C 1 ATOM 1021 O O . PRO A 1 127 ? -28.679 10.761 -40.448 1.00 47.46 ? 127 PRO A O 1 ATOM 1022 C CB . PRO A 1 127 ? -27.909 7.823 -39.400 1.00 45.89 ? 127 PRO A CB 1 ATOM 1023 C CG . PRO A 1 127 ? -26.544 7.395 -39.782 1.00 45.05 ? 127 PRO A CG 1 ATOM 1024 C CD . PRO A 1 127 ? -26.141 8.201 -40.967 1.00 44.58 ? 127 PRO A CD 1 ATOM 1025 N N . ARG A 1 128 ? -30.583 9.603 -40.118 1.00 49.42 ? 128 ARG A N 1 ATOM 1026 C CA . ARG A 1 128 ? -31.376 10.791 -39.793 1.00 51.52 ? 128 ARG A CA 1 ATOM 1027 C C . ARG A 1 128 ? -31.151 11.248 -38.346 1.00 52.21 ? 128 ARG A C 1 ATOM 1028 O O . ARG A 1 128 ? -30.885 10.418 -37.470 1.00 52.22 ? 128 ARG A O 1 ATOM 1029 C CB . ARG A 1 128 ? -32.860 10.528 -40.038 1.00 51.85 ? 128 ARG A CB 1 ATOM 1030 C CG . ARG A 1 128 ? -33.257 10.595 -41.506 1.00 54.05 ? 128 ARG A CG 1 ATOM 1031 C CD . ARG A 1 128 ? -34.771 10.635 -41.639 1.00 57.61 ? 128 ARG A CD 1 ATOM 1032 N NE . ARG A 1 128 ? -35.201 10.722 -43.034 1.00 60.59 ? 128 ARG A NE 1 ATOM 1033 C CZ . ARG A 1 128 ? -36.472 10.685 -43.430 1.00 61.49 ? 128 ARG A CZ 1 ATOM 1034 N NH1 . ARG A 1 128 ? -37.445 10.559 -42.537 1.00 61.95 ? 128 ARG A NH1 1 ATOM 1035 N NH2 . ARG A 1 128 ? -36.771 10.771 -44.719 1.00 61.51 ? 128 ARG A NH2 1 ATOM 1036 N N . PRO A 1 129 ? -31.252 12.572 -38.092 1.00 53.23 ? 129 PRO A N 1 ATOM 1037 C CA . PRO A 1 129 ? -31.082 13.095 -36.738 1.00 53.77 ? 129 PRO A CA 1 ATOM 1038 C C . PRO A 1 129 ? -31.969 12.365 -35.738 1.00 54.56 ? 129 PRO A C 1 ATOM 1039 O O . PRO A 1 129 ? -33.154 12.158 -35.997 1.00 54.81 ? 129 PRO A O 1 ATOM 1040 C CB . PRO A 1 129 ? -31.528 14.550 -36.871 1.00 53.82 ? 129 PRO A CB 1 ATOM 1041 C CG . PRO A 1 129 ? -31.209 14.904 -38.277 1.00 53.26 ? 129 PRO A CG 1 ATOM 1042 C CD . PRO A 1 129 ? -31.469 13.658 -39.073 1.00 53.28 ? 129 PRO A CD 1 ATOM 1043 N N . SER A 1 130 ? -31.376 11.945 -34.626 1.00 55.28 ? 130 SER A N 1 ATOM 1044 C CA . SER A 1 130 ? -32.114 11.350 -33.525 1.00 55.86 ? 130 SER A CA 1 ATOM 1045 C C . SER A 1 130 ? -32.033 12.295 -32.325 1.00 56.22 ? 130 SER A C 1 ATOM 1046 O O . SER A 1 130 ? -31.687 13.473 -32.474 1.00 56.62 ? 130 SER A O 1 ATOM 1047 C CB . SER A 1 130 ? -31.546 9.972 -33.178 1.00 55.88 ? 130 SER A CB 1 ATOM 1048 O OG . SER A 1 130 ? -30.443 10.084 -32.295 1.00 56.13 ? 130 SER A OG 1 ATOM 1049 N N . GLU A 1 131 ? -32.350 11.783 -31.141 1.00 56.39 ? 131 GLU A N 1 ATOM 1050 C CA . GLU A 1 131 ? -32.307 12.597 -29.932 1.00 56.49 ? 131 GLU A CA 1 ATOM 1051 C C . GLU A 1 131 ? -30.896 12.668 -29.353 1.00 55.82 ? 131 GLU A C 1 ATOM 1052 O O . GLU A 1 131 ? -30.549 13.649 -28.692 1.00 55.97 ? 131 GLU A O 1 ATOM 1053 C CB . GLU A 1 131 ? -33.307 12.082 -28.896 1.00 56.82 ? 131 GLU A CB 1 ATOM 1054 C CG . GLU A 1 131 ? -34.041 13.197 -28.179 1.00 58.95 ? 131 GLU A CG 1 ATOM 1055 C CD . GLU A 1 131 ? -35.550 13.077 -28.336 1.00 61.91 ? 131 GLU A CD 1 ATOM 1056 O OE1 . GLU A 1 131 ? -36.140 12.135 -27.756 1.00 64.02 ? 131 GLU A OE1 1 ATOM 1057 O OE2 . GLU A 1 131 ? -36.145 13.922 -29.047 1.00 62.45 ? 131 GLU A OE2 1 ATOM 1058 N N . LYS A 1 132 ? -30.091 11.636 -29.616 1.00 54.81 ? 132 LYS A N 1 ATOM 1059 C CA . LYS A 1 132 ? -28.677 11.621 -29.214 1.00 53.65 ? 132 LYS A CA 1 ATOM 1060 C C . LYS A 1 132 ? -27.715 12.207 -30.257 1.00 52.38 ? 132 LYS A C 1 ATOM 1061 O O . LYS A 1 132 ? -26.499 12.238 -30.025 1.00 52.22 ? 132 LYS A O 1 ATOM 1062 C CB . LYS A 1 132 ? -28.226 10.198 -28.837 1.00 53.84 ? 132 LYS A CB 1 ATOM 1063 C CG . LYS A 1 132 ? -28.718 9.711 -27.471 1.00 55.04 ? 132 LYS A CG 1 ATOM 1064 C CD . LYS A 1 132 ? -28.111 10.508 -26.310 1.00 56.02 ? 132 LYS A CD 1 ATOM 1065 C CE . LYS A 1 132 ? -28.979 10.404 -25.064 1.00 56.83 ? 132 LYS A CE 1 ATOM 1066 N NZ . LYS A 1 132 ? -28.559 11.353 -23.999 1.00 57.31 ? 132 LYS A NZ 1 ATOM 1067 N N . CYS A 1 133 ? -28.244 12.668 -31.393 1.00 50.67 ? 133 CYS A N 1 ATOM 1068 C CA . CYS A 1 133 ? -27.400 13.198 -32.478 1.00 48.97 ? 133 CYS A CA 1 ATOM 1069 C C . CYS A 1 133 ? -28.128 14.172 -33.413 1.00 48.56 ? 133 CYS A C 1 ATOM 1070 O O . CYS A 1 133 ? -28.997 13.763 -34.190 1.00 48.43 ? 133 CYS A O 1 ATOM 1071 C CB . CYS A 1 133 ? -26.789 12.051 -33.287 1.00 48.54 ? 133 CYS A CB 1 ATOM 1072 S SG . CYS A 1 133 ? -25.680 12.616 -34.579 1.00 46.60 ? 133 CYS A SG 1 ATOM 1073 N N . SER A 1 134 ? -27.762 15.454 -33.346 1.00 47.81 ? 134 SER A N 1 ATOM 1074 C CA . SER A 1 134 ? -28.438 16.481 -34.155 1.00 47.22 ? 134 SER A CA 1 ATOM 1075 C C . SER A 1 134 ? -28.149 16.325 -35.653 1.00 46.61 ? 134 SER A C 1 ATOM 1076 O O . SER A 1 134 ? -29.056 16.460 -36.464 1.00 46.76 ? 134 SER A O 1 ATOM 1077 C CB . SER A 1 134 ? -28.143 17.904 -33.653 1.00 47.04 ? 134 SER A CB 1 ATOM 1078 O OG . SER A 1 134 ? -26.779 18.238 -33.802 1.00 47.72 ? 134 SER A OG 1 ATOM 1079 N N . LYS A 1 135 ? -26.895 16.053 -36.014 1.00 45.62 ? 135 LYS A N 1 ATOM 1080 C CA . LYS A 1 135 ? -26.587 15.535 -37.353 1.00 44.76 ? 135 LYS A CA 1 ATOM 1081 C C . LYS A 1 135 ? -25.335 14.657 -37.418 1.00 43.34 ? 135 LYS A C 1 ATOM 1082 O O . LYS A 1 135 ? -24.325 14.942 -36.772 1.00 43.45 ? 135 LYS A O 1 ATOM 1083 C CB . LYS A 1 135 ? -26.584 16.630 -38.442 1.00 45.23 ? 135 LYS A CB 1 ATOM 1084 C CG . LYS A 1 135 ? -25.456 17.647 -38.406 1.00 47.01 ? 135 LYS A CG 1 ATOM 1085 C CD . LYS A 1 135 ? -25.889 18.924 -39.135 1.00 49.96 ? 135 LYS A CD 1 ATOM 1086 C CE . LYS A 1 135 ? -24.765 19.947 -39.245 1.00 52.00 ? 135 LYS A CE 1 ATOM 1087 N NZ . LYS A 1 135 ? -23.884 19.676 -40.436 1.00 53.60 ? 135 LYS A NZ 1 ATOM 1088 N N . TRP A 1 136 ? -25.435 13.581 -38.194 1.00 41.57 ? 136 TRP A N 1 ATOM 1089 C CA . TRP A 1 136 ? -24.297 12.729 -38.535 1.00 39.86 ? 136 TRP A CA 1 ATOM 1090 C C . TRP A 1 136 ? -23.541 13.285 -39.730 1.00 39.37 ? 136 TRP A C 1 ATOM 1091 O O . TRP A 1 136 ? -24.152 13.742 -40.698 1.00 39.68 ? 136 TRP A O 1 ATOM 1092 C CB . TRP A 1 136 ? -24.778 11.317 -38.864 1.00 39.18 ? 136 TRP A CB 1 ATOM 1093 C CG . TRP A 1 136 ? -25.279 10.613 -37.668 1.00 37.58 ? 136 TRP A CG 1 ATOM 1094 C CD1 . TRP A 1 136 ? -26.571 10.524 -37.254 1.00 36.09 ? 136 TRP A CD1 1 ATOM 1095 C CD2 . TRP A 1 136 ? -24.493 9.902 -36.708 1.00 35.59 ? 136 TRP A CD2 1 ATOM 1096 N NE1 . TRP A 1 136 ? -26.643 9.799 -36.093 1.00 35.28 ? 136 TRP A NE1 1 ATOM 1097 C CE2 . TRP A 1 136 ? -25.380 9.406 -35.734 1.00 35.29 ? 136 TRP A CE2 1 ATOM 1098 C CE3 . TRP A 1 136 ? -23.120 9.635 -36.578 1.00 34.58 ? 136 TRP A CE3 1 ATOM 1099 C CZ2 . TRP A 1 136 ? -24.945 8.653 -34.639 1.00 34.81 ? 136 TRP A CZ2 1 ATOM 1100 C CZ3 . TRP A 1 136 ? -22.685 8.892 -35.489 1.00 33.24 ? 136 TRP A CZ3 1 ATOM 1101 C CH2 . TRP A 1 136 ? -23.596 8.415 -34.532 1.00 33.97 ? 136 TRP A CH2 1 ATOM 1102 N N . ILE A 1 137 ? -22.218 13.251 -39.667 1.00 38.15 ? 137 ILE A N 1 ATOM 1103 C CA . ILE A 1 137 ? -21.408 13.734 -40.767 1.00 37.82 ? 137 ILE A CA 1 ATOM 1104 C C . ILE A 1 137 ? -20.448 12.654 -41.235 1.00 37.38 ? 137 ILE A C 1 ATOM 1105 O O . ILE A 1 137 ? -19.683 12.078 -40.442 1.00 36.70 ? 137 ILE A O 1 ATOM 1106 C CB . ILE A 1 137 ? -20.631 15.063 -40.426 1.00 38.61 ? 137 ILE A CB 1 ATOM 1107 C CG1 . ILE A 1 137 ? -21.590 16.218 -40.120 1.00 38.68 ? 137 ILE A CG1 1 ATOM 1108 C CG2 . ILE A 1 137 ? -19.707 15.480 -41.585 1.00 38.42 ? 137 ILE A CG2 1 ATOM 1109 C CD1 . ILE A 1 137 ? -22.024 16.309 -38.676 1.00 40.67 ? 137 ILE A CD1 1 ATOM 1110 N N . LEU A 1 138 ? -20.514 12.384 -42.534 1.00 36.86 ? 138 LEU A N 1 ATOM 1111 C CA . LEU A 1 138 ? -19.603 11.477 -43.198 1.00 36.65 ? 138 LEU A CA 1 ATOM 1112 C C . LEU A 1 138 ? -18.179 11.957 -42.971 1.00 37.02 ? 138 LEU A C 1 ATOM 1113 O O . LEU A 1 138 ? -17.851 13.116 -43.254 1.00 36.66 ? 138 LEU A O 1 ATOM 1114 C CB . LEU A 1 138 ? -19.923 11.446 -44.697 1.00 36.76 ? 138 LEU A CB 1 ATOM 1115 C CG . LEU A 1 138 ? -19.319 10.337 -45.557 1.00 36.33 ? 138 LEU A CG 1 ATOM 1116 C CD1 . LEU A 1 138 ? -19.714 8.953 -45.030 1.00 34.87 ? 138 LEU A CD1 1 ATOM 1117 C CD2 . LEU A 1 138 ? -19.785 10.526 -47.006 1.00 34.97 ? 138 LEU A CD2 1 ATOM 1118 N N . LEU A 1 139 ? -17.341 11.063 -42.453 1.00 36.91 ? 139 LEU A N 1 ATOM 1119 C CA . LEU A 1 139 ? -15.975 11.395 -42.084 1.00 37.86 ? 139 LEU A CA 1 ATOM 1120 C C . LEU A 1 139 ? -15.165 11.850 -43.301 1.00 38.47 ? 139 LEU A C 1 ATOM 1121 O O . LEU A 1 139 ? -14.304 12.724 -43.175 1.00 38.04 ? 139 LEU A O 1 ATOM 1122 C CB . LEU A 1 139 ? -15.306 10.192 -41.418 1.00 37.21 ? 139 LEU A CB 1 ATOM 1123 C CG . LEU A 1 139 ? -14.574 10.274 -40.066 1.00 38.01 ? 139 LEU A CG 1 ATOM 1124 C CD1 . LEU A 1 139 ? -14.786 11.566 -39.268 1.00 35.66 ? 139 LEU A CD1 1 ATOM 1125 C CD2 . LEU A 1 139 ? -14.981 9.085 -39.245 1.00 35.33 ? 139 LEU A CD2 1 ATOM 1126 N N . GLU A 1 140 ? -15.434 11.251 -44.462 1.00 39.10 ? 140 GLU A N 1 ATOM 1127 C CA . GLU A 1 140 ? -14.828 11.729 -45.707 1.00 40.59 ? 140 GLU A CA 1 ATOM 1128 C C . GLU A 1 140 ? -15.094 13.214 -45.961 1.00 40.32 ? 140 GLU A C 1 ATOM 1129 O O . GLU A 1 140 ? -14.167 13.957 -46.244 1.00 40.48 ? 140 GLU A O 1 ATOM 1130 C CB . GLU A 1 140 ? -15.234 10.874 -46.905 1.00 41.04 ? 140 GLU A CB 1 ATOM 1131 C CG . GLU A 1 140 ? -14.112 9.956 -47.338 1.00 44.30 ? 140 GLU A CG 1 ATOM 1132 C CD . GLU A 1 140 ? -14.580 8.811 -48.212 1.00 49.10 ? 140 GLU A CD 1 ATOM 1133 O OE1 . GLU A 1 140 ? -14.946 9.068 -49.386 1.00 50.99 ? 140 GLU A OE1 1 ATOM 1134 O OE2 . GLU A 1 140 ? -14.562 7.650 -47.725 1.00 50.49 ? 140 GLU A OE2 1 ATOM 1135 N N . ASP A 1 141 ? -16.345 13.642 -45.816 1.00 40.72 ? 141 ASP A N 1 ATOM 1136 C CA . ASP A 1 141 ? -16.707 15.061 -45.986 1.00 40.78 ? 141 ASP A CA 1 ATOM 1137 C C . ASP A 1 141 ? -16.047 15.956 -44.944 1.00 40.64 ? 141 ASP A C 1 ATOM 1138 O O . ASP A 1 141 ? -15.562 17.035 -45.273 1.00 40.81 ? 141 ASP A O 1 ATOM 1139 C CB . ASP A 1 141 ? -18.232 15.250 -45.972 1.00 41.06 ? 141 ASP A CB 1 ATOM 1140 C CG . ASP A 1 141 ? -18.908 14.604 -47.171 1.00 41.99 ? 141 ASP A CG 1 ATOM 1141 O OD1 . ASP A 1 141 ? -18.217 14.421 -48.195 1.00 43.65 ? 141 ASP A OD1 1 ATOM 1142 O OD2 . ASP A 1 141 ? -20.117 14.274 -47.097 1.00 41.15 ? 141 ASP A OD2 1 ATOM 1143 N N . TYR A 1 142 ? -16.008 15.489 -43.697 1.00 40.17 ? 142 TYR A N 1 ATOM 1144 C CA . TYR A 1 142 ? -15.435 16.252 -42.590 1.00 39.66 ? 142 TYR A CA 1 ATOM 1145 C C . TYR A 1 142 ? -13.957 16.554 -42.826 1.00 39.25 ? 142 TYR A C 1 ATOM 1146 O O . TYR A 1 142 ? -13.502 17.682 -42.617 1.00 38.84 ? 142 TYR A O 1 ATOM 1147 C CB . TYR A 1 142 ? -15.606 15.471 -41.280 1.00 39.74 ? 142 TYR A CB 1 ATOM 1148 C CG . TYR A 1 142 ? -15.565 16.303 -40.017 1.00 40.07 ? 142 TYR A CG 1 ATOM 1149 C CD1 . TYR A 1 142 ? -16.725 16.525 -39.275 1.00 40.83 ? 142 TYR A CD1 1 ATOM 1150 C CD2 . TYR A 1 142 ? -14.373 16.845 -39.549 1.00 39.56 ? 142 TYR A CD2 1 ATOM 1151 C CE1 . TYR A 1 142 ? -16.701 17.279 -38.106 1.00 41.44 ? 142 TYR A CE1 1 ATOM 1152 C CE2 . TYR A 1 142 ? -14.336 17.604 -38.388 1.00 40.60 ? 142 TYR A CE2 1 ATOM 1153 C CZ . TYR A 1 142 ? -15.504 17.809 -37.666 1.00 42.10 ? 142 TYR A CZ 1 ATOM 1154 O OH . TYR A 1 142 ? -15.475 18.553 -36.506 1.00 43.16 ? 142 TYR A OH 1 ATOM 1155 N N . ARG A 1 143 ? -13.210 15.536 -43.245 1.00 38.83 ? 143 ARG A N 1 ATOM 1156 C CA . ARG A 1 143 ? -11.771 15.675 -43.457 1.00 39.14 ? 143 ARG A CA 1 ATOM 1157 C C . ARG A 1 143 ? -11.427 16.574 -44.666 1.00 39.60 ? 143 ARG A C 1 ATOM 1158 O O . ARG A 1 143 ? -10.323 17.131 -44.734 1.00 39.00 ? 143 ARG A O 1 ATOM 1159 C CB . ARG A 1 143 ? -11.084 14.301 -43.542 1.00 38.79 ? 143 ARG A CB 1 ATOM 1160 C CG . ARG A 1 143 ? -10.982 13.573 -42.186 1.00 39.09 ? 143 ARG A CG 1 ATOM 1161 C CD . ARG A 1 143 ? -10.190 12.263 -42.288 1.00 39.90 ? 143 ARG A CD 1 ATOM 1162 N NE . ARG A 1 143 ? -9.947 11.616 -40.994 1.00 38.19 ? 143 ARG A NE 1 ATOM 1163 C CZ . ARG A 1 143 ? -10.493 10.463 -40.595 1.00 38.62 ? 143 ARG A CZ 1 ATOM 1164 N NH1 . ARG A 1 143 ? -11.344 9.787 -41.378 1.00 36.73 ? 143 ARG A NH1 1 ATOM 1165 N NH2 . ARG A 1 143 ? -10.176 9.973 -39.402 1.00 36.20 ? 143 ARG A NH2 1 ATOM 1166 N N . LYS A 1 144 ? -12.381 16.729 -45.591 1.00 40.00 ? 144 LYS A N 1 ATOM 1167 C CA . LYS A 1 144 ? -12.226 17.663 -46.711 1.00 40.87 ? 144 LYS A CA 1 ATOM 1168 C C . LYS A 1 144 ? -12.289 19.095 -46.214 1.00 40.74 ? 144 LYS A C 1 ATOM 1169 O O . LYS A 1 144 ? -11.706 19.978 -46.829 1.00 40.97 ? 144 LYS A O 1 ATOM 1170 C CB . LYS A 1 144 ? -13.282 17.435 -47.805 1.00 40.81 ? 144 LYS A CB 1 ATOM 1171 C CG . LYS A 1 144 ? -13.174 16.074 -48.469 1.00 42.55 ? 144 LYS A CG 1 ATOM 1172 C CD . LYS A 1 144 ? -14.042 15.944 -49.725 1.00 46.14 ? 144 LYS A CD 1 ATOM 1173 C CE . LYS A 1 144 ? -13.720 14.645 -50.475 1.00 46.18 ? 144 LYS A CE 1 ATOM 1174 N NZ . LYS A 1 144 ? -14.004 14.762 -51.938 1.00 48.75 ? 144 LYS A NZ 1 ATOM 1175 N N . ARG A 1 145 ? -12.973 19.311 -45.089 1.00 40.66 ? 145 ARG A N 1 ATOM 1176 C CA . ARG A 1 145 ? -13.190 20.657 -44.553 1.00 40.66 ? 145 ARG A CA 1 ATOM 1177 C C . ARG A 1 145 ? -12.261 21.095 -43.412 1.00 40.50 ? 145 ARG A C 1 ATOM 1178 O O . ARG A 1 145 ? -12.367 22.228 -42.955 1.00 40.55 ? 145 ARG A O 1 ATOM 1179 C CB . ARG A 1 145 ? -14.640 20.839 -44.105 1.00 41.10 ? 145 ARG A CB 1 ATOM 1180 C CG . ARG A 1 145 ? -15.692 20.541 -45.160 1.00 43.07 ? 145 ARG A CG 1 ATOM 1181 C CD . ARG A 1 145 ? -17.071 20.572 -44.521 1.00 47.27 ? 145 ARG A CD 1 ATOM 1182 N NE . ARG A 1 145 ? -17.984 19.592 -45.110 1.00 51.17 ? 145 ARG A NE 1 ATOM 1183 C CZ . ARG A 1 145 ? -18.957 18.968 -44.444 1.00 52.57 ? 145 ARG A CZ 1 ATOM 1184 N NH1 . ARG A 1 145 ? -19.152 19.206 -43.148 1.00 53.29 ? 145 ARG A NH1 1 ATOM 1185 N NH2 . ARG A 1 145 ? -19.736 18.095 -45.072 1.00 52.90 ? 145 ARG A NH2 1 ATOM 1186 N N . VAL A 1 146 ? -11.364 20.227 -42.943 1.00 40.61 ? 146 VAL A N 1 ATOM 1187 C CA . VAL A 1 146 ? -10.435 20.633 -41.881 1.00 41.13 ? 146 VAL A CA 1 ATOM 1188 C C . VAL A 1 146 ? -9.092 21.105 -42.428 1.00 41.71 ? 146 VAL A C 1 ATOM 1189 O O . VAL A 1 146 ? -8.566 20.561 -43.403 1.00 41.57 ? 146 VAL A O 1 ATOM 1190 C CB . VAL A 1 146 ? -10.234 19.557 -40.752 1.00 40.94 ? 146 VAL A CB 1 ATOM 1191 C CG1 . VAL A 1 146 ? -11.566 19.169 -40.143 1.00 40.84 ? 146 VAL A CG1 1 ATOM 1192 C CG2 . VAL A 1 146 ? -9.504 18.330 -41.266 1.00 40.12 ? 146 VAL A CG2 1 ATOM 1193 N N . GLN A 1 147 ? -8.546 22.120 -41.766 1.00 42.85 ? 147 GLN A N 1 ATOM 1194 C CA . GLN A 1 147 ? -7.326 22.789 -42.208 1.00 43.89 ? 147 GLN A CA 1 ATOM 1195 C C . GLN A 1 147 ? -6.091 21.889 -42.072 1.00 43.80 ? 147 GLN A C 1 ATOM 1196 O O . GLN A 1 147 ? -5.217 21.907 -42.939 1.00 43.88 ? 147 GLN A O 1 ATOM 1197 C CB . GLN A 1 147 ? -7.135 24.101 -41.434 1.00 44.56 ? 147 GLN A CB 1 ATOM 1198 C CG . GLN A 1 147 ? -6.806 25.330 -42.315 1.00 46.29 ? 147 GLN A CG 1 ATOM 1199 C CD . GLN A 1 147 ? -8.050 26.107 -42.754 1.00 48.83 ? 147 GLN A CD 1 ATOM 1200 O OE1 . GLN A 1 147 ? -9.140 25.540 -42.886 1.00 49.92 ? 147 GLN A OE1 1 ATOM 1201 N NE2 . GLN A 1 147 ? -7.883 27.413 -42.998 1.00 49.37 ? 147 GLN A NE2 1 ATOM 1202 N N . ASN A 1 148 ? -6.045 21.094 -40.996 1.00 43.51 ? 148 ASN A N 1 ATOM 1203 C CA . ASN A 1 148 ? -4.941 20.173 -40.712 1.00 42.74 ? 148 ASN A CA 1 ATOM 1204 C C . ASN A 1 148 ? -5.472 18.793 -40.281 1.00 42.29 ? 148 ASN A C 1 ATOM 1205 O O . ASN A 1 148 ? -5.893 18.596 -39.134 1.00 41.49 ? 148 ASN A O 1 ATOM 1206 C CB . ASN A 1 148 ? -3.998 20.776 -39.650 1.00 43.02 ? 148 ASN A CB 1 ATOM 1207 C CG . ASN A 1 148 ? -2.822 19.856 -39.284 1.00 44.30 ? 148 ASN A CG 1 ATOM 1208 O OD1 . ASN A 1 148 ? -2.752 18.695 -39.705 1.00 44.22 ? 148 ASN A OD1 1 ATOM 1209 N ND2 . ASN A 1 148 ? -1.886 20.389 -38.489 1.00 46.75 ? 148 ASN A ND2 1 ATOM 1210 N N . VAL A 1 149 ? -5.432 17.847 -41.218 1.00 41.57 ? 149 VAL A N 1 ATOM 1211 C CA . VAL A 1 149 ? -5.984 16.515 -41.028 1.00 41.10 ? 149 VAL A CA 1 ATOM 1212 C C . VAL A 1 149 ? -5.227 15.757 -39.933 1.00 40.74 ? 149 VAL A C 1 ATOM 1213 O O . VAL A 1 149 ? -5.846 15.110 -39.092 1.00 40.77 ? 149 VAL A O 1 ATOM 1214 C CB . VAL A 1 149 ? -6.013 15.713 -42.361 1.00 41.44 ? 149 VAL A CB 1 ATOM 1215 C CG1 . VAL A 1 149 ? -6.578 14.313 -42.158 1.00 40.92 ? 149 VAL A CG1 1 ATOM 1216 C CG2 . VAL A 1 149 ? -6.842 16.456 -43.417 1.00 40.82 ? 149 VAL A CG2 1 ATOM 1217 N N . THR A 1 150 ? -3.898 15.882 -39.939 1.00 40.24 ? 150 THR A N 1 ATOM 1218 C CA . THR A 1 150 ? -3.010 15.198 -38.993 1.00 39.69 ? 150 THR A CA 1 ATOM 1219 C C . THR A 1 150 ? -3.398 15.490 -37.537 1.00 39.07 ? 150 THR A C 1 ATOM 1220 O O . THR A 1 150 ? -3.483 14.580 -36.725 1.00 38.90 ? 150 THR A O 1 ATOM 1221 C CB . THR A 1 150 ? -1.500 15.502 -39.306 1.00 39.98 ? 150 THR A CB 1 ATOM 1222 O OG1 . THR A 1 150 ? -1.157 14.896 -40.558 1.00 40.06 ? 150 THR A OG1 1 ATOM 1223 C CG2 . THR A 1 150 ? -0.563 14.934 -38.243 1.00 39.78 ? 150 THR A CG2 1 ATOM 1224 N N . GLU A 1 151 ? -3.689 16.754 -37.246 1.00 38.48 ? 151 GLU A N 1 ATOM 1225 C CA . GLU A 1 151 ? -4.116 17.198 -35.925 1.00 37.76 ? 151 GLU A CA 1 ATOM 1226 C C . GLU A 1 151 ? -5.523 16.709 -35.574 1.00 36.91 ? 151 GLU A C 1 ATOM 1227 O O . GLU A 1 151 ? -5.797 16.375 -34.415 1.00 35.67 ? 151 GLU A O 1 ATOM 1228 C CB . GLU A 1 151 ? -4.031 18.735 -35.829 1.00 38.12 ? 151 GLU A CB 1 ATOM 1229 C CG . GLU A 1 151 ? -4.577 19.354 -34.525 1.00 39.54 ? 151 GLU A CG 1 ATOM 1230 C CD . GLU A 1 151 ? -3.944 18.765 -33.244 1.00 42.73 ? 151 GLU A CD 1 ATOM 1231 O OE1 . GLU A 1 151 ? -2.794 18.252 -33.309 1.00 44.44 ? 151 GLU A OE1 1 ATOM 1232 O OE2 . GLU A 1 151 ? -4.600 18.824 -32.170 1.00 41.75 ? 151 GLU A OE2 1 ATOM 1233 N N . PHE A 1 152 ? -6.404 16.665 -36.576 1.00 35.85 ? 152 PHE A N 1 ATOM 1234 C CA . PHE A 1 152 ? -7.773 16.169 -36.379 1.00 34.83 ? 152 PHE A CA 1 ATOM 1235 C C . PHE A 1 152 ? -7.728 14.697 -35.982 1.00 34.36 ? 152 PHE A C 1 ATOM 1236 O O . PHE A 1 152 ? -8.379 14.279 -35.014 1.00 33.93 ? 152 PHE A O 1 ATOM 1237 C CB . PHE A 1 152 ? -8.609 16.342 -37.652 1.00 34.75 ? 152 PHE A CB 1 ATOM 1238 C CG . PHE A 1 152 ? -9.958 15.687 -37.583 1.00 34.12 ? 152 PHE A CG 1 ATOM 1239 C CD1 . PHE A 1 152 ? -10.971 16.227 -36.784 1.00 33.41 ? 152 PHE A CD1 1 ATOM 1240 C CD2 . PHE A 1 152 ? -10.217 14.519 -38.305 1.00 33.73 ? 152 PHE A CD2 1 ATOM 1241 C CE1 . PHE A 1 152 ? -12.231 15.614 -36.706 1.00 33.57 ? 152 PHE A CE1 1 ATOM 1242 C CE2 . PHE A 1 152 ? -11.473 13.902 -38.241 1.00 32.92 ? 152 PHE A CE2 1 ATOM 1243 C CZ . PHE A 1 152 ? -12.482 14.453 -37.434 1.00 33.59 ? 152 PHE A CZ 1 ATOM 1244 N N . ASP A 1 153 ? -6.957 13.923 -36.740 1.00 33.66 ? 153 ASP A N 1 ATOM 1245 C CA . ASP A 1 153 ? -6.789 12.503 -36.463 1.00 33.93 ? 153 ASP A CA 1 ATOM 1246 C C . ASP A 1 153 ? -6.217 12.280 -35.051 1.00 34.31 ? 153 ASP A C 1 ATOM 1247 O O . ASP A 1 153 ? -6.769 11.508 -34.273 1.00 34.54 ? 153 ASP A O 1 ATOM 1248 C CB . ASP A 1 153 ? -5.937 11.827 -37.548 1.00 33.30 ? 153 ASP A CB 1 ATOM 1249 C CG . ASP A 1 153 ? -6.706 11.610 -38.869 1.00 33.08 ? 153 ASP A CG 1 ATOM 1250 O OD1 . ASP A 1 153 ? -7.918 11.901 -38.951 1.00 31.22 ? 153 ASP A OD1 1 ATOM 1251 O OD2 . ASP A 1 153 ? -6.092 11.125 -39.841 1.00 33.24 ? 153 ASP A OD2 1 ATOM 1252 N N . ASP A 1 154 ? -5.142 12.988 -34.707 1.00 34.40 ? 154 ASP A N 1 ATOM 1253 C CA . ASP A 1 154 ? -4.603 12.922 -33.352 1.00 34.37 ? 154 ASP A CA 1 ATOM 1254 C C . ASP A 1 154 ? -5.619 13.271 -32.269 1.00 33.18 ? 154 ASP A C 1 ATOM 1255 O O . ASP A 1 154 ? -5.597 12.665 -31.203 1.00 32.67 ? 154 ASP A O 1 ATOM 1256 C CB . ASP A 1 154 ? -3.345 13.782 -33.207 1.00 35.58 ? 154 ASP A CB 1 ATOM 1257 C CG . ASP A 1 154 ? -2.191 13.257 -34.039 1.00 38.69 ? 154 ASP A CG 1 ATOM 1258 O OD1 . ASP A 1 154 ? -2.336 12.161 -34.633 1.00 42.59 ? 154 ASP A OD1 1 ATOM 1259 O OD2 . ASP A 1 154 ? -1.145 13.945 -34.116 1.00 43.38 ? 154 ASP A OD2 1 ATOM 1260 N N . SER A 1 155 ? -6.498 14.235 -32.527 1.00 31.26 ? 155 SER A N 1 ATOM 1261 C CA . SER A 1 155 ? -7.536 14.557 -31.556 1.00 30.64 ? 155 SER A CA 1 ATOM 1262 C C . SER A 1 155 ? -8.506 13.376 -31.361 1.00 29.80 ? 155 SER A C 1 ATOM 1263 O O . SER A 1 155 ? -9.018 13.161 -30.256 1.00 28.68 ? 155 SER A O 1 ATOM 1264 C CB . SER A 1 155 ? -8.268 15.862 -31.902 1.00 30.97 ? 155 SER A CB 1 ATOM 1265 O OG . SER A 1 155 ? -9.328 15.677 -32.831 1.00 32.66 ? 155 SER A OG 1 ATOM 1266 N N . LEU A 1 156 ? -8.732 12.600 -32.423 1.00 28.43 ? 156 LEU A N 1 ATOM 1267 C CA . LEU A 1 156 ? -9.535 11.386 -32.293 1.00 28.42 ? 156 LEU A CA 1 ATOM 1268 C C . LEU A 1 156 ? -8.825 10.367 -31.399 1.00 27.97 ? 156 LEU A C 1 ATOM 1269 O O . LEU A 1 156 ? -9.431 9.805 -30.502 1.00 27.48 ? 156 LEU A O 1 ATOM 1270 C CB . LEU A 1 156 ? -9.873 10.771 -33.660 1.00 28.26 ? 156 LEU A CB 1 ATOM 1271 C CG . LEU A 1 156 ? -10.700 11.573 -34.684 1.00 28.06 ? 156 LEU A CG 1 ATOM 1272 C CD1 . LEU A 1 156 ? -11.101 10.640 -35.826 1.00 28.06 ? 156 LEU A CD1 1 ATOM 1273 C CD2 . LEU A 1 156 ? -11.923 12.188 -34.064 1.00 27.18 ? 156 LEU A CD2 1 ATOM 1274 N N . LEU A 1 157 ? -7.535 10.158 -31.643 1.00 28.23 ? 157 LEU A N 1 ATOM 1275 C CA . LEU A 1 157 ? -6.727 9.259 -30.838 1.00 29.05 ? 157 LEU A CA 1 ATOM 1276 C C . LEU A 1 157 ? -6.758 9.635 -29.346 1.00 29.08 ? 157 LEU A C 1 ATOM 1277 O O . LEU A 1 157 ? -6.828 8.760 -28.497 1.00 28.53 ? 157 LEU A O 1 ATOM 1278 C CB . LEU A 1 157 ? -5.297 9.197 -31.384 1.00 29.55 ? 157 LEU A CB 1 ATOM 1279 C CG . LEU A 1 157 ? -4.391 8.117 -30.789 1.00 31.60 ? 157 LEU A CG 1 ATOM 1280 C CD1 . LEU A 1 157 ? -5.021 6.713 -30.907 1.00 34.20 ? 157 LEU A CD1 1 ATOM 1281 C CD2 . LEU A 1 157 ? -3.015 8.143 -31.438 1.00 33.46 ? 157 LEU A CD2 1 ATOM 1282 N N . ARG A 1 158 ? -6.763 10.935 -29.038 1.00 29.38 ? 158 ARG A N 1 ATOM 1283 C CA . ARG A 1 158 ? -6.867 11.418 -27.645 1.00 29.30 ? 158 ARG A CA 1 ATOM 1284 C C . ARG A 1 158 ? -8.214 11.143 -27.001 1.00 28.86 ? 158 ARG A C 1 ATOM 1285 O O . ARG A 1 158 ? -8.302 10.989 -25.782 1.00 28.67 ? 158 ARG A O 1 ATOM 1286 C CB . ARG A 1 158 ? -6.555 12.913 -27.540 1.00 29.56 ? 158 ARG A CB 1 ATOM 1287 C CG . ARG A 1 158 ? -5.123 13.278 -27.878 1.00 31.71 ? 158 ARG A CG 1 ATOM 1288 C CD . ARG A 1 158 ? -4.824 14.756 -27.564 1.00 36.41 ? 158 ARG A CD 1 ATOM 1289 N NE . ARG A 1 158 ? -5.953 15.666 -27.832 1.00 40.68 ? 158 ARG A NE 1 ATOM 1290 C CZ . ARG A 1 158 ? -6.026 16.516 -28.860 1.00 42.09 ? 158 ARG A CZ 1 ATOM 1291 N NH1 . ARG A 1 158 ? -5.039 16.585 -29.750 1.00 43.69 ? 158 ARG A NH1 1 ATOM 1292 N NH2 . ARG A 1 158 ? -7.090 17.307 -29.002 1.00 42.24 ? 158 ARG A NH2 1 ATOM 1293 N N . ASN A 1 159 ? -9.266 11.075 -27.813 1.00 27.66 ? 159 ASN A N 1 ATOM 1294 C CA . ASN A 1 159 ? -10.562 10.682 -27.305 1.00 27.40 ? 159 ASN A CA 1 ATOM 1295 C C . ASN A 1 159 ? -10.700 9.186 -27.041 1.00 25.59 ? 159 ASN A C 1 ATOM 1296 O O . ASN A 1 159 ? -11.673 8.776 -26.427 1.00 26.35 ? 159 ASN A O 1 ATOM 1297 C CB . ASN A 1 159 ? -11.670 11.092 -28.268 1.00 28.28 ? 159 ASN A CB 1 ATOM 1298 C CG . ASN A 1 159 ? -12.001 12.557 -28.183 1.00 33.40 ? 159 ASN A CG 1 ATOM 1299 O OD1 . ASN A 1 159 ? -12.975 12.943 -27.533 1.00 36.55 ? 159 ASN A OD1 1 ATOM 1300 N ND2 . ASN A 1 159 ? -11.197 13.390 -28.842 1.00 38.50 ? 159 ASN A ND2 1 ATOM 1301 N N . PHE A 1 160 ? -9.761 8.383 -27.524 1.00 23.55 ? 160 PHE A N 1 ATOM 1302 C CA . PHE A 1 160 ? -9.892 6.919 -27.472 1.00 23.54 ? 160 PHE A CA 1 ATOM 1303 C C . PHE A 1 160 ? -9.090 6.270 -26.321 1.00 22.57 ? 160 PHE A C 1 ATOM 1304 O O . PHE A 1 160 ? -9.172 5.055 -26.127 1.00 22.18 ? 160 PHE A O 1 ATOM 1305 C CB . PHE A 1 160 ? -9.423 6.278 -28.790 1.00 22.79 ? 160 PHE A CB 1 ATOM 1306 C CG . PHE A 1 160 ? -10.342 6.501 -29.980 1.00 24.56 ? 160 PHE A CG 1 ATOM 1307 C CD1 . PHE A 1 160 ? -11.408 7.406 -29.934 1.00 23.56 ? 160 PHE A CD1 1 ATOM 1308 C CD2 . PHE A 1 160 ? -10.087 5.828 -31.185 1.00 23.09 ? 160 PHE A CD2 1 ATOM 1309 C CE1 . PHE A 1 160 ? -12.208 7.609 -31.062 1.00 25.68 ? 160 PHE A CE1 1 ATOM 1310 C CE2 . PHE A 1 160 ? -10.880 6.034 -32.306 1.00 23.80 ? 160 PHE A CE2 1 ATOM 1311 C CZ . PHE A 1 160 ? -11.938 6.932 -32.242 1.00 24.27 ? 160 PHE A CZ 1 ATOM 1312 N N . THR A 1 161 ? -8.294 7.062 -25.594 1.00 22.61 ? 161 THR A N 1 ATOM 1313 C CA . THR A 1 161 ? -7.505 6.528 -24.464 1.00 22.24 ? 161 THR A CA 1 ATOM 1314 C C . THR A 1 161 ? -7.505 7.495 -23.281 1.00 21.87 ? 161 THR A C 1 ATOM 1315 O O . THR A 1 161 ? -7.830 8.692 -23.435 1.00 21.12 ? 161 THR A O 1 ATOM 1316 C CB . THR A 1 161 ? -6.014 6.245 -24.807 1.00 22.12 ? 161 THR A CB 1 ATOM 1317 O OG1 . THR A 1 161 ? -5.278 7.473 -24.740 1.00 23.47 ? 161 THR A OG1 1 ATOM 1318 C CG2 . THR A 1 161 ? -5.839 5.579 -26.184 1.00 22.62 ? 161 THR A CG2 1 ATOM 1319 N N . LEU A 1 162 ? -7.127 6.983 -22.106 1.00 20.74 ? 162 LEU A N 1 ATOM 1320 C CA . LEU A 1 162 ? -7.002 7.838 -20.908 1.00 20.87 ? 162 LEU A CA 1 ATOM 1321 C C . LEU A 1 162 ? -5.667 8.579 -20.878 1.00 21.25 ? 162 LEU A C 1 ATOM 1322 O O . LEU A 1 162 ? -5.484 9.529 -20.103 1.00 20.63 ? 162 LEU A O 1 ATOM 1323 C CB . LEU A 1 162 ? -7.175 7.007 -19.637 1.00 20.00 ? 162 LEU A CB 1 ATOM 1324 C CG . LEU A 1 162 ? -8.542 6.375 -19.451 1.00 20.34 ? 162 LEU A CG 1 ATOM 1325 C CD1 . LEU A 1 162 ? -8.467 5.325 -18.320 1.00 22.90 ? 162 LEU A CD1 1 ATOM 1326 C CD2 . LEU A 1 162 ? -9.573 7.459 -19.169 1.00 20.85 ? 162 LEU A CD2 1 ATOM 1327 N N . VAL A 1 163 ? -4.732 8.116 -21.705 1.00 21.84 ? 163 VAL A N 1 ATOM 1328 C CA . VAL A 1 163 ? -3.371 8.670 -21.752 1.00 23.75 ? 163 VAL A CA 1 ATOM 1329 C C . VAL A 1 163 ? -3.392 10.198 -21.820 1.00 25.19 ? 163 VAL A C 1 ATOM 1330 O O . VAL A 1 163 ? -4.129 10.794 -22.627 1.00 24.77 ? 163 VAL A O 1 ATOM 1331 C CB . VAL A 1 163 ? -2.562 8.082 -22.912 1.00 23.39 ? 163 VAL A CB 1 ATOM 1332 C CG1 . VAL A 1 163 ? -1.186 8.739 -23.030 1.00 24.26 ? 163 VAL A CG1 1 ATOM 1333 C CG2 . VAL A 1 163 ? -2.428 6.587 -22.729 1.00 23.30 ? 163 VAL A CG2 1 ATOM 1334 N N . THR A 1 164 ? -2.611 10.816 -20.939 1.00 26.21 ? 164 THR A N 1 ATOM 1335 C CA . THR A 1 164 ? -2.552 12.260 -20.829 1.00 27.59 ? 164 THR A CA 1 ATOM 1336 C C . THR A 1 164 ? -1.296 12.702 -20.066 1.00 28.45 ? 164 THR A C 1 ATOM 1337 O O . THR A 1 164 ? -0.712 11.924 -19.308 1.00 27.46 ? 164 THR A O 1 ATOM 1338 C CB . THR A 1 164 ? -3.855 12.845 -20.162 1.00 27.87 ? 164 THR A CB 1 ATOM 1339 O OG1 . THR A 1 164 ? -3.800 14.273 -20.179 1.00 30.24 ? 164 THR A OG1 1 ATOM 1340 C CG2 . THR A 1 164 ? -4.039 12.375 -18.716 1.00 27.78 ? 164 THR A CG2 1 ATOM 1341 N N . GLN A 1 165 ? -0.871 13.947 -20.289 1.00 29.12 ? 165 GLN A N 1 ATOM 1342 C CA . GLN A 1 165 ? 0.126 14.573 -19.434 1.00 30.26 ? 165 GLN A CA 1 ATOM 1343 C C . GLN A 1 165 ? -0.650 14.975 -18.193 1.00 29.72 ? 165 GLN A C 1 ATOM 1344 O O . GLN A 1 165 ? -1.850 15.132 -18.260 1.00 30.47 ? 165 GLN A O 1 ATOM 1345 C CB . GLN A 1 165 ? 0.720 15.814 -20.116 1.00 30.95 ? 165 GLN A CB 1 ATOM 1346 C CG . GLN A 1 165 ? 1.755 15.533 -21.209 1.00 34.90 ? 165 GLN A CG 1 ATOM 1347 C CD . GLN A 1 165 ? 2.270 16.809 -21.904 1.00 41.16 ? 165 GLN A CD 1 ATOM 1348 O OE1 . GLN A 1 165 ? 2.548 16.802 -23.110 1.00 44.00 ? 165 GLN A OE1 1 ATOM 1349 N NE2 . GLN A 1 165 ? 2.403 17.899 -21.145 1.00 42.08 ? 165 GLN A NE2 1 ATOM 1350 N N . HIS A 1 166 ? 0.012 15.127 -17.062 1.00 29.26 ? 166 HIS A N 1 ATOM 1351 C CA . HIS A 1 166 ? -0.673 15.559 -15.826 1.00 29.36 ? 166 HIS A CA 1 ATOM 1352 C C . HIS A 1 166 ? -2.002 14.856 -15.478 1.00 28.31 ? 166 HIS A C 1 ATOM 1353 O O . HIS A 1 166 ? -3.022 15.511 -15.232 1.00 28.63 ? 166 HIS A O 1 ATOM 1354 C CB . HIS A 1 166 ? -0.802 17.089 -15.823 1.00 29.98 ? 166 HIS A CB 1 ATOM 1355 C CG . HIS A 1 166 ? 0.497 17.767 -16.113 1.00 32.23 ? 166 HIS A CG 1 ATOM 1356 N ND1 . HIS A 1 166 ? 1.584 17.670 -15.268 1.00 34.93 ? 166 HIS A ND1 1 ATOM 1357 C CD2 . HIS A 1 166 ? 0.912 18.482 -17.184 1.00 35.84 ? 166 HIS A CD2 1 ATOM 1358 C CE1 . HIS A 1 166 ? 2.604 18.326 -15.791 1.00 37.24 ? 166 HIS A CE1 1 ATOM 1359 N NE2 . HIS A 1 166 ? 2.221 18.834 -16.951 1.00 38.18 ? 166 HIS A NE2 1 ATOM 1360 N N . PRO A 1 167 ? -1.978 13.508 -15.408 1.00 27.43 ? 167 PRO A N 1 ATOM 1361 C CA . PRO A 1 167 ? -3.189 12.767 -15.056 1.00 26.46 ? 167 PRO A CA 1 ATOM 1362 C C . PRO A 1 167 ? -3.670 13.092 -13.644 1.00 26.22 ? 167 PRO A C 1 ATOM 1363 O O . PRO A 1 167 ? -4.857 12.949 -13.358 1.00 24.35 ? 167 PRO A O 1 ATOM 1364 C CB . PRO A 1 167 ? -2.750 11.305 -15.159 1.00 26.40 ? 167 PRO A CB 1 ATOM 1365 C CG . PRO A 1 167 ? -1.256 11.341 -14.930 1.00 25.92 ? 167 PRO A CG 1 ATOM 1366 C CD . PRO A 1 167 ? -0.828 12.604 -15.622 1.00 26.93 ? 167 PRO A CD 1 ATOM 1367 N N . GLU A 1 168 ? -2.754 13.552 -12.793 1.00 26.69 ? 168 GLU A N 1 ATOM 1368 C CA . GLU A 1 168 ? -3.099 14.032 -11.446 1.00 28.40 ? 168 GLU A CA 1 ATOM 1369 C C . GLU A 1 168 ? -3.995 15.279 -11.488 1.00 28.60 ? 168 GLU A C 1 ATOM 1370 O O . GLU A 1 168 ? -4.863 15.416 -10.640 1.00 29.95 ? 168 GLU A O 1 ATOM 1371 C CB . GLU A 1 168 ? -1.837 14.260 -10.578 1.00 28.51 ? 168 GLU A CB 1 ATOM 1372 C CG . GLU A 1 168 ? -1.030 15.545 -10.895 1.00 30.73 ? 168 GLU A CG 1 ATOM 1373 C CD . GLU A 1 168 ? -0.174 15.465 -12.170 1.00 35.04 ? 168 GLU A CD 1 ATOM 1374 O OE1 . GLU A 1 168 ? -0.008 14.355 -12.759 1.00 35.91 ? 168 GLU A OE1 1 ATOM 1375 O OE2 . GLU A 1 168 ? 0.352 16.531 -12.577 1.00 35.61 ? 168 GLU A OE2 1 ATOM 1376 N N . VAL A 1 169 ? -3.789 16.159 -12.478 1.00 28.88 ? 169 VAL A N 1 ATOM 1377 C CA . VAL A 1 169 ? -4.634 17.346 -12.702 1.00 29.51 ? 169 VAL A CA 1 ATOM 1378 C C . VAL A 1 169 ? -5.914 16.965 -13.449 1.00 29.15 ? 169 VAL A C 1 ATOM 1379 O O . VAL A 1 169 ? -7.008 17.378 -13.071 1.00 29.41 ? 169 VAL A O 1 ATOM 1380 C CB . VAL A 1 169 ? -3.890 18.457 -13.525 1.00 29.66 ? 169 VAL A CB 1 ATOM 1381 C CG1 . VAL A 1 169 ? -4.815 19.656 -13.829 1.00 30.94 ? 169 VAL A CG1 1 ATOM 1382 C CG2 . VAL A 1 169 ? -2.645 18.929 -12.800 1.00 29.86 ? 169 VAL A CG2 1 ATOM 1383 N N . ILE A 1 170 ? -5.771 16.160 -14.498 1.00 28.91 ? 170 ILE A N 1 ATOM 1384 C CA . ILE A 1 170 ? -6.919 15.743 -15.307 1.00 28.88 ? 170 ILE A CA 1 ATOM 1385 C C . ILE A 1 170 ? -7.896 14.850 -14.506 1.00 27.84 ? 170 ILE A C 1 ATOM 1386 O O . ILE A 1 170 ? -9.100 15.067 -14.541 1.00 27.70 ? 170 ILE A O 1 ATOM 1387 C CB . ILE A 1 170 ? -6.457 15.052 -16.639 1.00 29.13 ? 170 ILE A CB 1 ATOM 1388 C CG1 . ILE A 1 170 ? -5.436 15.931 -17.394 1.00 32.10 ? 170 ILE A CG1 1 ATOM 1389 C CG2 . ILE A 1 170 ? -7.628 14.725 -17.554 1.00 29.55 ? 170 ILE A CG2 1 ATOM 1390 C CD1 . ILE A 1 170 ? -5.854 17.432 -17.599 1.00 32.36 ? 170 ILE A CD1 1 ATOM 1391 N N . TYR A 1 171 ? -7.380 13.854 -13.784 1.00 26.13 ? 171 TYR A N 1 ATOM 1392 C CA . TYR A 1 171 ? -8.260 12.921 -13.082 1.00 24.93 ? 171 TYR A CA 1 ATOM 1393 C C . TYR A 1 171 ? -8.090 13.089 -11.597 1.00 24.45 ? 171 TYR A C 1 ATOM 1394 O O . TYR A 1 171 ? -7.222 12.461 -10.989 1.00 25.05 ? 171 TYR A O 1 ATOM 1395 C CB . TYR A 1 171 ? -8.017 11.470 -13.512 1.00 24.63 ? 171 TYR A CB 1 ATOM 1396 C CG . TYR A 1 171 ? -7.914 11.256 -15.013 1.00 23.85 ? 171 TYR A CG 1 ATOM 1397 C CD1 . TYR A 1 171 ? -8.995 11.547 -15.859 1.00 22.40 ? 171 TYR A CD1 1 ATOM 1398 C CD2 . TYR A 1 171 ? -6.742 10.748 -15.581 1.00 24.02 ? 171 TYR A CD2 1 ATOM 1399 C CE1 . TYR A 1 171 ? -8.901 11.351 -17.238 1.00 24.18 ? 171 TYR A CE1 1 ATOM 1400 C CE2 . TYR A 1 171 ? -6.636 10.528 -16.953 1.00 23.75 ? 171 TYR A CE2 1 ATOM 1401 C CZ . TYR A 1 171 ? -7.719 10.835 -17.779 1.00 25.16 ? 171 TYR A CZ 1 ATOM 1402 O OH . TYR A 1 171 ? -7.613 10.631 -19.137 1.00 24.42 ? 171 TYR A OH 1 ATOM 1403 N N . THR A 1 172 ? -8.938 13.930 -11.019 1.00 24.09 ? 172 THR A N 1 ATOM 1404 C CA . THR A 1 172 ? -8.771 14.412 -9.646 1.00 24.49 ? 172 THR A CA 1 ATOM 1405 C C . THR A 1 172 ? -9.220 13.374 -8.606 1.00 23.56 ? 172 THR A C 1 ATOM 1406 O O . THR A 1 172 ? -8.771 13.409 -7.465 1.00 23.52 ? 172 THR A O 1 ATOM 1407 C CB . THR A 1 172 ? -9.570 15.729 -9.407 1.00 24.80 ? 172 THR A CB 1 ATOM 1408 O OG1 . THR A 1 172 ? -10.924 15.534 -9.832 1.00 26.50 ? 172 THR A OG1 1 ATOM 1409 C CG2 . THR A 1 172 ? -8.973 16.880 -10.198 1.00 26.00 ? 172 THR A CG2 1 ATOM 1410 N N . ASN A 1 173 ? -10.112 12.471 -9.001 1.00 22.64 ? 173 ASN A N 1 ATOM 1411 C CA . ASN A 1 173 ? -10.586 11.401 -8.119 1.00 22.10 ? 173 ASN A CA 1 ATOM 1412 C C . ASN A 1 173 ? -11.063 10.182 -8.921 1.00 21.82 ? 173 ASN A C 1 ATOM 1413 O O . ASN A 1 173 ? -11.140 10.244 -10.163 1.00 20.50 ? 173 ASN A O 1 ATOM 1414 C CB . ASN A 1 173 ? -11.688 11.927 -7.185 1.00 21.76 ? 173 ASN A CB 1 ATOM 1415 C CG . ASN A 1 173 ? -12.936 12.322 -7.938 1.00 22.62 ? 173 ASN A CG 1 ATOM 1416 O OD1 . ASN A 1 173 ? -13.492 11.525 -8.687 1.00 19.84 ? 173 ASN A OD1 1 ATOM 1417 N ND2 . ASN A 1 173 ? -13.397 13.555 -7.726 1.00 21.04 ? 173 ASN A ND2 1 ATOM 1418 N N . GLN A 1 174 ? -11.411 9.096 -8.223 1.00 20.68 ? 174 GLN A N 1 ATOM 1419 C CA . GLN A 1 174 ? -11.699 7.831 -8.892 1.00 21.55 ? 174 GLN A CA 1 ATOM 1420 C C . GLN A 1 174 ? -12.975 7.885 -9.713 1.00 21.71 ? 174 GLN A C 1 ATOM 1421 O O . GLN A 1 174 ? -13.101 7.158 -10.700 1.00 21.57 ? 174 GLN A O 1 ATOM 1422 C CB . GLN A 1 174 ? -11.745 6.659 -7.891 1.00 21.86 ? 174 GLN A CB 1 ATOM 1423 C CG . GLN A 1 174 ? -10.331 6.194 -7.431 1.00 22.28 ? 174 GLN A CG 1 ATOM 1424 C CD . GLN A 1 174 ? -10.353 5.340 -6.157 1.00 24.13 ? 174 GLN A CD 1 ATOM 1425 O OE1 . GLN A 1 174 ? -9.402 5.352 -5.374 1.00 26.53 ? 174 GLN A OE1 1 ATOM 1426 N NE2 . GLN A 1 174 ? -11.424 4.601 -5.954 1.00 23.89 ? 174 GLN A NE2 1 ATOM 1427 N N . ASN A 1 175 ? -13.925 8.720 -9.294 1.00 21.41 ? 175 ASN A N 1 ATOM 1428 C CA . ASN A 1 175 ? -15.165 8.885 -10.064 1.00 21.58 ? 175 ASN A CA 1 ATOM 1429 C C . ASN A 1 175 ? -14.930 9.581 -11.398 1.00 21.05 ? 175 ASN A C 1 ATOM 1430 O O . ASN A 1 175 ? -15.480 9.174 -12.407 1.00 20.89 ? 175 ASN A O 1 ATOM 1431 C CB . ASN A 1 175 ? -16.260 9.595 -9.252 1.00 21.55 ? 175 ASN A CB 1 ATOM 1432 C CG . ASN A 1 175 ? -16.913 8.677 -8.216 1.00 22.91 ? 175 ASN A CG 1 ATOM 1433 O OD1 . ASN A 1 175 ? -16.689 7.454 -8.192 1.00 23.51 ? 175 ASN A OD1 1 ATOM 1434 N ND2 . ASN A 1 175 ? -17.733 9.266 -7.356 1.00 22.40 ? 175 ASN A ND2 1 ATOM 1435 N N . VAL A 1 176 ? -14.090 10.613 -11.404 1.00 21.50 ? 176 VAL A N 1 ATOM 1436 C CA . VAL A 1 176 ? -13.762 11.313 -12.647 1.00 21.59 ? 176 VAL A CA 1 ATOM 1437 C C . VAL A 1 176 ? -13.050 10.390 -13.653 1.00 22.00 ? 176 VAL A C 1 ATOM 1438 O O . VAL A 1 176 ? -13.413 10.361 -14.843 1.00 21.85 ? 176 VAL A O 1 ATOM 1439 C CB . VAL A 1 176 ? -12.897 12.552 -12.364 1.00 22.17 ? 176 VAL A CB 1 ATOM 1440 C CG1 . VAL A 1 176 ? -12.480 13.268 -13.673 1.00 21.67 ? 176 VAL A CG1 1 ATOM 1441 C CG2 . VAL A 1 176 ? -13.652 13.494 -11.382 1.00 23.25 ? 176 VAL A CG2 1 ATOM 1442 N N . VAL A 1 177 ? -12.046 9.637 -13.193 1.00 20.36 ? 177 VAL A N 1 ATOM 1443 C CA . VAL A 1 177 ? -11.374 8.722 -14.105 1.00 20.32 ? 177 VAL A CA 1 ATOM 1444 C C . VAL A 1 177 ? -12.336 7.642 -14.650 1.00 19.91 ? 177 VAL A C 1 ATOM 1445 O O . VAL A 1 177 ? -12.317 7.336 -15.855 1.00 19.63 ? 177 VAL A O 1 ATOM 1446 C CB . VAL A 1 177 ? -10.028 8.171 -13.523 1.00 19.68 ? 177 VAL A CB 1 ATOM 1447 C CG1 . VAL A 1 177 ? -10.281 7.081 -12.439 1.00 20.68 ? 177 VAL A CG1 1 ATOM 1448 C CG2 . VAL A 1 177 ? -9.162 7.648 -14.630 1.00 20.23 ? 177 VAL A CG2 1 ATOM 1449 N N . TRP A 1 178 ? -13.197 7.096 -13.794 1.00 20.07 ? 178 TRP A N 1 ATOM 1450 C CA . TRP A 1 178 ? -14.198 6.111 -14.254 1.00 21.27 ? 178 TRP A CA 1 ATOM 1451 C C . TRP A 1 178 ? -15.198 6.698 -15.251 1.00 21.87 ? 178 TRP A C 1 ATOM 1452 O O . TRP A 1 178 ? -15.587 6.030 -16.197 1.00 21.99 ? 178 TRP A O 1 ATOM 1453 C CB . TRP A 1 178 ? -14.930 5.419 -13.091 1.00 20.51 ? 178 TRP A CB 1 ATOM 1454 C CG . TRP A 1 178 ? -14.257 4.146 -12.701 1.00 21.75 ? 178 TRP A CG 1 ATOM 1455 C CD1 . TRP A 1 178 ? -13.288 3.988 -11.745 1.00 23.06 ? 178 TRP A CD1 1 ATOM 1456 C CD2 . TRP A 1 178 ? -14.451 2.850 -13.294 1.00 21.80 ? 178 TRP A CD2 1 ATOM 1457 N NE1 . TRP A 1 178 ? -12.893 2.671 -11.686 1.00 24.40 ? 178 TRP A NE1 1 ATOM 1458 C CE2 . TRP A 1 178 ? -13.588 1.952 -12.628 1.00 23.07 ? 178 TRP A CE2 1 ATOM 1459 C CE3 . TRP A 1 178 ? -15.279 2.362 -14.318 1.00 23.91 ? 178 TRP A CE3 1 ATOM 1460 C CZ2 . TRP A 1 178 ? -13.529 0.584 -12.948 1.00 24.48 ? 178 TRP A CZ2 1 ATOM 1461 C CZ3 . TRP A 1 178 ? -15.214 1.002 -14.646 1.00 23.35 ? 178 TRP A CZ3 1 ATOM 1462 C CH2 . TRP A 1 178 ? -14.335 0.130 -13.961 1.00 22.36 ? 178 TRP A CH2 1 ATOM 1463 N N . SER A 1 179 ? -15.603 7.944 -15.027 1.00 22.24 ? 179 SER A N 1 ATOM 1464 C CA . SER A 1 179 ? -16.519 8.627 -15.933 1.00 23.25 ? 179 SER A CA 1 ATOM 1465 C C . SER A 1 179 ? -15.886 8.796 -17.325 1.00 22.42 ? 179 SER A C 1 ATOM 1466 O O . SER A 1 179 ? -16.507 8.485 -18.334 1.00 22.15 ? 179 SER A O 1 ATOM 1467 C CB . SER A 1 179 ? -16.935 9.978 -15.343 1.00 23.72 ? 179 SER A CB 1 ATOM 1468 O OG . SER A 1 179 ? -17.649 10.708 -16.325 1.00 28.06 ? 179 SER A OG 1 ATOM 1469 N N . LYS A 1 180 ? -14.632 9.223 -17.368 1.00 22.62 ? 180 LYS A N 1 ATOM 1470 C CA . LYS A 1 180 ? -13.864 9.246 -18.610 1.00 23.43 ? 180 LYS A CA 1 ATOM 1471 C C . LYS A 1 180 ? -13.683 7.870 -19.261 1.00 22.83 ? 180 LYS A C 1 ATOM 1472 O O . LYS A 1 180 ? -13.858 7.749 -20.468 1.00 23.07 ? 180 LYS A O 1 ATOM 1473 C CB . LYS A 1 180 ? -12.501 9.914 -18.403 1.00 23.61 ? 180 LYS A CB 1 ATOM 1474 C CG . LYS A 1 180 ? -12.594 11.370 -17.984 1.00 27.85 ? 180 LYS A CG 1 ATOM 1475 C CD . LYS A 1 180 ? -13.083 12.244 -19.154 1.00 33.38 ? 180 LYS A CD 1 ATOM 1476 C CE . LYS A 1 180 ? -13.390 13.658 -18.683 1.00 37.51 ? 180 LYS A CE 1 ATOM 1477 N NZ . LYS A 1 180 ? -13.760 14.533 -19.837 1.00 39.93 ? 180 LYS A NZ 1 ATOM 1478 N N . PHE A 1 181 ? -13.316 6.860 -18.466 1.00 23.44 ? 181 PHE A N 1 ATOM 1479 C CA . PHE A 1 181 ? -13.128 5.451 -18.909 1.00 23.90 ? 181 PHE A CA 1 ATOM 1480 C C . PHE A 1 181 ? -14.358 4.975 -19.657 1.00 25.14 ? 181 PHE A C 1 ATOM 1481 O O . PHE A 1 181 ? -14.280 4.562 -20.822 1.00 25.59 ? 181 PHE A O 1 ATOM 1482 C CB . PHE A 1 181 ? -12.926 4.575 -17.652 1.00 23.86 ? 181 PHE A CB 1 ATOM 1483 C CG . PHE A 1 181 ? -12.260 3.222 -17.875 1.00 22.90 ? 181 PHE A CG 1 ATOM 1484 C CD1 . PHE A 1 181 ? -11.258 3.027 -18.825 1.00 22.89 ? 181 PHE A CD1 1 ATOM 1485 C CD2 . PHE A 1 181 ? -12.582 2.157 -17.028 1.00 23.27 ? 181 PHE A CD2 1 ATOM 1486 C CE1 . PHE A 1 181 ? -10.617 1.774 -18.959 1.00 21.59 ? 181 PHE A CE1 1 ATOM 1487 C CE2 . PHE A 1 181 ? -11.963 0.891 -17.155 1.00 22.97 ? 181 PHE A CE2 1 ATOM 1488 C CZ . PHE A 1 181 ? -10.973 0.702 -18.133 1.00 22.50 ? 181 PHE A CZ 1 ATOM 1489 N N . GLU A 1 182 ? -15.492 5.048 -18.970 1.00 25.98 ? 182 GLU A N 1 ATOM 1490 C CA . GLU A 1 182 ? -16.812 4.641 -19.492 1.00 27.87 ? 182 GLU A CA 1 ATOM 1491 C C . GLU A 1 182 ? -17.195 5.380 -20.758 1.00 27.35 ? 182 GLU A C 1 ATOM 1492 O O . GLU A 1 182 ? -17.678 4.771 -21.713 1.00 27.99 ? 182 GLU A O 1 ATOM 1493 C CB . GLU A 1 182 ? -17.887 4.846 -18.412 1.00 28.15 ? 182 GLU A CB 1 ATOM 1494 C CG . GLU A 1 182 ? -17.773 3.802 -17.307 1.00 33.35 ? 182 GLU A CG 1 ATOM 1495 C CD . GLU A 1 182 ? -18.427 4.213 -15.981 1.00 40.91 ? 182 GLU A CD 1 ATOM 1496 O OE1 . GLU A 1 182 ? -18.878 3.294 -15.263 1.00 43.24 ? 182 GLU A OE1 1 ATOM 1497 O OE2 . GLU A 1 182 ? -18.480 5.431 -15.643 1.00 42.20 ? 182 GLU A OE2 1 ATOM 1498 N N . THR A 1 183 ? -16.940 6.687 -20.772 1.00 27.35 ? 183 THR A N 1 ATOM 1499 C CA . THR A 1 183 ? -17.189 7.522 -21.951 1.00 27.02 ? 183 THR A CA 1 ATOM 1500 C C . THR A 1 183 ? -16.406 7.026 -23.176 1.00 26.16 ? 183 THR A C 1 ATOM 1501 O O . THR A 1 183 ? -16.934 7.036 -24.302 1.00 25.50 ? 183 THR A O 1 ATOM 1502 C CB . THR A 1 183 ? -16.910 9.017 -21.641 1.00 27.13 ? 183 THR A CB 1 ATOM 1503 O OG1 . THR A 1 183 ? -17.846 9.453 -20.651 1.00 28.49 ? 183 THR A OG1 1 ATOM 1504 C CG2 . THR A 1 183 ? -17.083 9.892 -22.864 1.00 29.42 ? 183 THR A CG2 1 ATOM 1505 N N . ILE A 1 184 ? -15.172 6.571 -22.960 1.00 24.74 ? 184 ILE A N 1 ATOM 1506 C CA . ILE A 1 184 ? -14.397 5.970 -24.045 1.00 24.70 ? 184 ILE A CA 1 ATOM 1507 C C . ILE A 1 184 ? -15.078 4.747 -24.657 1.00 24.68 ? 184 ILE A C 1 ATOM 1508 O O . ILE A 1 184 ? -15.098 4.612 -25.871 1.00 23.62 ? 184 ILE A O 1 ATOM 1509 C CB . ILE A 1 184 ? -12.954 5.617 -23.636 1.00 24.48 ? 184 ILE A CB 1 ATOM 1510 C CG1 . ILE A 1 184 ? -12.173 6.902 -23.339 1.00 24.77 ? 184 ILE A CG1 1 ATOM 1511 C CG2 . ILE A 1 184 ? -12.281 4.771 -24.732 1.00 24.34 ? 184 ILE A CG2 1 ATOM 1512 C CD1 . ILE A 1 184 ? -10.853 6.670 -22.648 1.00 27.12 ? 184 ILE A CD1 1 ATOM 1513 N N . PHE A 1 185 ? -15.616 3.860 -23.820 1.00 24.98 ? 185 PHE A N 1 ATOM 1514 C CA . PHE A 1 185 ? -16.299 2.672 -24.327 1.00 26.40 ? 185 PHE A CA 1 ATOM 1515 C C . PHE A 1 185 ? -17.505 3.087 -25.172 1.00 26.30 ? 185 PHE A C 1 ATOM 1516 O O . PHE A 1 185 ? -17.760 2.514 -26.238 1.00 26.15 ? 185 PHE A O 1 ATOM 1517 C CB . PHE A 1 185 ? -16.691 1.694 -23.188 1.00 26.63 ? 185 PHE A CB 1 ATOM 1518 C CG . PHE A 1 185 ? -15.500 1.025 -22.506 1.00 29.52 ? 185 PHE A CG 1 ATOM 1519 C CD1 . PHE A 1 185 ? -15.024 -0.212 -22.942 1.00 34.59 ? 185 PHE A CD1 1 ATOM 1520 C CD2 . PHE A 1 185 ? -14.875 1.610 -21.418 1.00 32.10 ? 185 PHE A CD2 1 ATOM 1521 C CE1 . PHE A 1 185 ? -13.932 -0.841 -22.312 1.00 34.68 ? 185 PHE A CE1 1 ATOM 1522 C CE2 . PHE A 1 185 ? -13.796 0.994 -20.783 1.00 33.08 ? 185 PHE A CE2 1 ATOM 1523 C CZ . PHE A 1 185 ? -13.324 -0.227 -21.236 1.00 34.36 ? 185 PHE A CZ 1 ATOM 1524 N N . PHE A 1 186 ? -18.222 4.109 -24.720 1.00 26.64 ? 186 PHE A N 1 ATOM 1525 C CA . PHE A 1 186 ? -19.353 4.640 -25.481 1.00 26.94 ? 186 PHE A CA 1 ATOM 1526 C C . PHE A 1 186 ? -18.930 5.162 -26.874 1.00 26.94 ? 186 PHE A C 1 ATOM 1527 O O . PHE A 1 186 ? -19.572 4.840 -27.898 1.00 26.98 ? 186 PHE A O 1 ATOM 1528 C CB . PHE A 1 186 ? -20.099 5.719 -24.680 1.00 27.38 ? 186 PHE A CB 1 ATOM 1529 C CG . PHE A 1 186 ? -21.190 6.388 -25.460 1.00 29.55 ? 186 PHE A CG 1 ATOM 1530 C CD1 . PHE A 1 186 ? -20.961 7.606 -26.100 1.00 31.13 ? 186 PHE A CD1 1 ATOM 1531 C CD2 . PHE A 1 186 ? -22.422 5.765 -25.621 1.00 31.59 ? 186 PHE A CD2 1 ATOM 1532 C CE1 . PHE A 1 186 ? -21.958 8.214 -26.862 1.00 31.00 ? 186 PHE A CE1 1 ATOM 1533 C CE2 . PHE A 1 186 ? -23.432 6.367 -26.387 1.00 32.07 ? 186 PHE A CE2 1 ATOM 1534 C CZ . PHE A 1 186 ? -23.199 7.592 -26.998 1.00 31.48 ? 186 PHE A CZ 1 ATOM 1535 N N . THR A 1 187 ? -17.842 5.933 -26.906 1.00 25.99 ? 187 THR A N 1 ATOM 1536 C CA . THR A 1 187 ? -17.341 6.580 -28.127 1.00 25.71 ? 187 THR A CA 1 ATOM 1537 C C . THR A 1 187 ? -16.912 5.574 -29.201 1.00 25.97 ? 187 THR A C 1 ATOM 1538 O O . THR A 1 187 ? -17.312 5.689 -30.356 1.00 26.34 ? 187 THR A O 1 ATOM 1539 C CB . THR A 1 187 ? -16.160 7.519 -27.799 1.00 26.17 ? 187 THR A CB 1 ATOM 1540 O OG1 . THR A 1 187 ? -16.641 8.638 -27.048 1.00 25.07 ? 187 THR A OG1 1 ATOM 1541 C CG2 . THR A 1 187 ? -15.450 8.006 -29.064 1.00 26.01 ? 187 THR A CG2 1 ATOM 1542 N N . ILE A 1 188 ? -16.095 4.596 -28.822 1.00 25.02 ? 188 ILE A N 1 ATOM 1543 C CA . ILE A 1 188 ? -15.525 3.683 -29.800 1.00 24.69 ? 188 ILE A CA 1 ATOM 1544 C C . ILE A 1 188 ? -16.485 2.549 -30.181 1.00 24.72 ? 188 ILE A C 1 ATOM 1545 O O . ILE A 1 188 ? -16.257 1.851 -31.164 1.00 23.16 ? 188 ILE A O 1 ATOM 1546 C CB . ILE A 1 188 ? -14.166 3.079 -29.315 1.00 25.32 ? 188 ILE A CB 1 ATOM 1547 C CG1 . ILE A 1 188 ? -14.403 2.125 -28.128 1.00 25.00 ? 188 ILE A CG1 1 ATOM 1548 C CG2 . ILE A 1 188 ? -13.111 4.212 -29.025 1.00 21.15 ? 188 ILE A CG2 1 ATOM 1549 C CD1 . ILE A 1 188 ? -13.152 1.426 -27.626 1.00 25.37 ? 188 ILE A CD1 1 ATOM 1550 N N . SER A 1 189 ? -17.560 2.388 -29.411 1.00 25.21 ? 189 SER A N 1 ATOM 1551 C CA . SER A 1 189 ? -18.451 1.245 -29.581 1.00 26.79 ? 189 SER A CA 1 ATOM 1552 C C . SER A 1 189 ? -19.086 1.185 -30.987 1.00 26.02 ? 189 SER A C 1 ATOM 1553 O O . SER A 1 189 ? -19.147 0.123 -31.586 1.00 26.38 ? 189 SER A O 1 ATOM 1554 C CB . SER A 1 189 ? -19.513 1.195 -28.473 1.00 27.05 ? 189 SER A CB 1 ATOM 1555 O OG . SER A 1 189 ? -20.590 0.338 -28.821 1.00 29.63 ? 189 SER A OG 1 ATOM 1556 N N . GLY A 1 190 ? -19.518 2.320 -31.521 1.00 26.39 ? 190 GLY A N 1 ATOM 1557 C CA . GLY A 1 190 ? -20.092 2.348 -32.878 1.00 25.52 ? 190 GLY A CA 1 ATOM 1558 C C . GLY A 1 190 ? -19.093 1.962 -33.955 1.00 25.01 ? 190 GLY A C 1 ATOM 1559 O O . GLY A 1 190 ? -19.479 1.522 -35.040 1.00 25.22 ? 190 GLY A O 1 ATOM 1560 N N . LEU A 1 191 ? -17.805 2.135 -33.682 1.00 24.06 ? 191 LEU A N 1 ATOM 1561 C CA . LEU A 1 191 ? -16.792 1.717 -34.633 1.00 24.20 ? 191 LEU A CA 1 ATOM 1562 C C . LEU A 1 191 ? -16.634 0.196 -34.605 1.00 24.93 ? 191 LEU A C 1 ATOM 1563 O O . LEU A 1 191 ? -16.705 -0.463 -35.650 1.00 24.58 ? 191 LEU A O 1 ATOM 1564 C CB . LEU A 1 191 ? -15.442 2.394 -34.359 1.00 24.27 ? 191 LEU A CB 1 ATOM 1565 C CG . LEU A 1 191 ? -15.315 3.909 -34.594 1.00 24.04 ? 191 LEU A CG 1 ATOM 1566 C CD1 . LEU A 1 191 ? -13.986 4.390 -34.074 1.00 23.17 ? 191 LEU A CD1 1 ATOM 1567 C CD2 . LEU A 1 191 ? -15.462 4.235 -36.091 1.00 22.58 ? 191 LEU A CD2 1 ATOM 1568 N N . ILE A 1 192 ? -16.459 -0.352 -33.402 1.00 24.83 ? 192 ILE A N 1 ATOM 1569 C CA . ILE A 1 192 ? -16.088 -1.760 -33.226 1.00 24.98 ? 192 ILE A CA 1 ATOM 1570 C C . ILE A 1 192 ? -17.255 -2.710 -33.520 1.00 24.67 ? 192 ILE A C 1 ATOM 1571 O O . ILE A 1 192 ? -17.046 -3.804 -34.040 1.00 25.24 ? 192 ILE A O 1 ATOM 1572 C CB . ILE A 1 192 ? -15.544 -1.995 -31.798 1.00 24.56 ? 192 ILE A CB 1 ATOM 1573 C CG1 . ILE A 1 192 ? -14.310 -1.101 -31.572 1.00 25.86 ? 192 ILE A CG1 1 ATOM 1574 C CG2 . ILE A 1 192 ? -15.225 -3.476 -31.544 1.00 26.24 ? 192 ILE A CG2 1 ATOM 1575 C CD1 . ILE A 1 192 ? -13.738 -1.164 -30.132 1.00 23.01 ? 192 ILE A CD1 1 ATOM 1576 N N . HIS A 1 193 ? -18.473 -2.290 -33.209 1.00 24.15 ? 193 HIS A N 1 ATOM 1577 C CA . HIS A 1 193 ? -19.626 -3.178 -33.387 1.00 24.74 ? 193 HIS A CA 1 ATOM 1578 C C . HIS A 1 193 ? -20.236 -3.201 -34.816 1.00 23.99 ? 193 HIS A C 1 ATOM 1579 O O . HIS A 1 193 ? -21.291 -3.788 -35.028 1.00 23.96 ? 193 HIS A O 1 ATOM 1580 C CB . HIS A 1 193 ? -20.678 -2.920 -32.315 1.00 24.58 ? 193 HIS A CB 1 ATOM 1581 C CG . HIS A 1 193 ? -20.191 -3.217 -30.930 1.00 28.09 ? 193 HIS A CG 1 ATOM 1582 N ND1 . HIS A 1 193 ? -20.287 -4.469 -30.349 1.00 32.68 ? 193 HIS A ND1 1 ATOM 1583 C CD2 . HIS A 1 193 ? -19.574 -2.431 -30.019 1.00 28.82 ? 193 HIS A CD2 1 ATOM 1584 C CE1 . HIS A 1 193 ? -19.770 -4.430 -29.132 1.00 29.42 ? 193 HIS A CE1 1 ATOM 1585 N NE2 . HIS A 1 193 ? -19.330 -3.206 -28.909 1.00 30.77 ? 193 HIS A NE2 1 ATOM 1586 N N . TYR A 1 194 ? -19.560 -2.590 -35.786 1.00 23.73 ? 194 TYR A N 1 ATOM 1587 C CA . TYR A 1 194 ? -19.956 -2.725 -37.197 1.00 23.92 ? 194 TYR A CA 1 ATOM 1588 C C . TYR A 1 194 ? -19.340 -4.054 -37.650 1.00 23.69 ? 194 TYR A C 1 ATOM 1589 O O . TYR A 1 194 ? -18.136 -4.248 -37.501 1.00 23.82 ? 194 TYR A O 1 ATOM 1590 C CB . TYR A 1 194 ? -19.485 -1.495 -38.000 1.00 23.64 ? 194 TYR A CB 1 ATOM 1591 C CG . TYR A 1 194 ? -19.603 -1.582 -39.515 1.00 24.94 ? 194 TYR A CG 1 ATOM 1592 C CD1 . TYR A 1 194 ? -20.834 -1.836 -40.139 1.00 26.00 ? 194 TYR A CD1 1 ATOM 1593 C CD2 . TYR A 1 194 ? -18.477 -1.397 -40.327 1.00 25.80 ? 194 TYR A CD2 1 ATOM 1594 C CE1 . TYR A 1 194 ? -20.933 -1.912 -41.547 1.00 27.34 ? 194 TYR A CE1 1 ATOM 1595 C CE2 . TYR A 1 194 ? -18.565 -1.455 -41.739 1.00 26.57 ? 194 TYR A CE2 1 ATOM 1596 C CZ . TYR A 1 194 ? -19.794 -1.712 -42.333 1.00 28.41 ? 194 TYR A CZ 1 ATOM 1597 O OH . TYR A 1 194 ? -19.867 -1.786 -43.714 1.00 31.61 ? 194 TYR A OH 1 ATOM 1598 N N . ALA A 1 195 ? -20.172 -4.983 -38.144 1.00 23.39 ? 195 ALA A N 1 ATOM 1599 C CA . ALA A 1 195 ? -19.750 -6.382 -38.434 1.00 24.07 ? 195 ALA A CA 1 ATOM 1600 C C . ALA A 1 195 ? -18.397 -6.619 -39.127 1.00 24.04 ? 195 ALA A C 1 ATOM 1601 O O . ALA A 1 195 ? -17.640 -7.505 -38.701 1.00 24.33 ? 195 ALA A O 1 ATOM 1602 C CB . ALA A 1 195 ? -20.877 -7.177 -39.171 1.00 23.67 ? 195 ALA A CB 1 ATOM 1603 N N . PRO A 1 196 ? -18.102 -5.895 -40.224 1.00 23.79 ? 196 PRO A N 1 ATOM 1604 C CA . PRO A 1 196 ? -16.780 -6.159 -40.833 1.00 23.94 ? 196 PRO A CA 1 ATOM 1605 C C . PRO A 1 196 ? -15.619 -5.666 -39.947 1.00 23.60 ? 196 PRO A C 1 ATOM 1606 O O . PRO A 1 196 ? -14.530 -6.247 -39.965 1.00 23.25 ? 196 PRO A O 1 ATOM 1607 C CB . PRO A 1 196 ? -16.801 -5.361 -42.149 1.00 24.05 ? 196 PRO A CB 1 ATOM 1608 C CG . PRO A 1 196 ? -18.254 -4.933 -42.355 1.00 25.03 ? 196 PRO A CG 1 ATOM 1609 C CD . PRO A 1 196 ? -18.914 -4.944 -41.007 1.00 23.86 ? 196 PRO A CD 1 ATOM 1610 N N . VAL A 1 197 ? -15.852 -4.604 -39.187 1.00 23.92 ? 197 VAL A N 1 ATOM 1611 C CA . VAL A 1 197 ? -14.826 -4.102 -38.255 1.00 23.90 ? 197 VAL A CA 1 ATOM 1612 C C . VAL A 1 197 ? -14.668 -5.080 -37.071 1.00 23.91 ? 197 VAL A C 1 ATOM 1613 O O . VAL A 1 197 ? -13.542 -5.423 -36.688 1.00 24.28 ? 197 VAL A O 1 ATOM 1614 C CB . VAL A 1 197 ? -15.124 -2.673 -37.745 1.00 23.56 ? 197 VAL A CB 1 ATOM 1615 C CG1 . VAL A 1 197 ? -14.092 -2.271 -36.662 1.00 23.20 ? 197 VAL A CG1 1 ATOM 1616 C CG2 . VAL A 1 197 ? -15.092 -1.664 -38.903 1.00 22.52 ? 197 VAL A CG2 1 ATOM 1617 N N . PHE A 1 198 ? -15.799 -5.526 -36.521 1.00 23.47 ? 198 PHE A N 1 ATOM 1618 C CA . PHE A 1 198 ? -15.819 -6.517 -35.441 1.00 23.53 ? 198 PHE A CA 1 ATOM 1619 C C . PHE A 1 198 ? -14.938 -7.737 -35.740 1.00 23.70 ? 198 PHE A C 1 ATOM 1620 O O . PHE A 1 198 ? -14.094 -8.110 -34.934 1.00 23.62 ? 198 PHE A O 1 ATOM 1621 C CB . PHE A 1 198 ? -17.256 -6.948 -35.111 1.00 22.81 ? 198 PHE A CB 1 ATOM 1622 C CG . PHE A 1 198 ? -17.351 -7.866 -33.930 1.00 24.62 ? 198 PHE A CG 1 ATOM 1623 C CD1 . PHE A 1 198 ? -17.096 -7.399 -32.645 1.00 24.98 ? 198 PHE A CD1 1 ATOM 1624 C CD2 . PHE A 1 198 ? -17.675 -9.209 -34.097 1.00 25.75 ? 198 PHE A CD2 1 ATOM 1625 C CE1 . PHE A 1 198 ? -17.162 -8.248 -31.558 1.00 24.42 ? 198 PHE A CE1 1 ATOM 1626 C CE2 . PHE A 1 198 ? -17.752 -10.061 -33.006 1.00 25.73 ? 198 PHE A CE2 1 ATOM 1627 C CZ . PHE A 1 198 ? -17.496 -9.571 -31.732 1.00 25.23 ? 198 PHE A CZ 1 ATOM 1628 N N . ARG A 1 199 ? -15.128 -8.348 -36.903 1.00 23.47 ? 199 ARG A N 1 ATOM 1629 C CA . ARG A 1 199 ? -14.267 -9.451 -37.331 1.00 23.26 ? 199 ARG A CA 1 ATOM 1630 C C . ARG A 1 199 ? -12.778 -9.097 -37.386 1.00 22.53 ? 199 ARG A C 1 ATOM 1631 O O . ARG A 1 199 ? -11.938 -9.864 -36.899 1.00 21.63 ? 199 ARG A O 1 ATOM 1632 C CB . ARG A 1 199 ? -14.722 -9.954 -38.706 1.00 23.96 ? 199 ARG A CB 1 ATOM 1633 C CG . ARG A 1 199 ? -15.999 -10.738 -38.676 1.00 25.50 ? 199 ARG A CG 1 ATOM 1634 C CD . ARG A 1 199 ? -16.435 -11.134 -40.103 1.00 28.70 ? 199 ARG A CD 1 ATOM 1635 N NE . ARG A 1 199 ? -17.876 -11.200 -40.042 1.00 34.19 ? 199 ARG A NE 1 ATOM 1636 C CZ . ARG A 1 199 ? -18.714 -10.390 -40.664 1.00 31.53 ? 199 ARG A CZ 1 ATOM 1637 N NH1 . ARG A 1 199 ? -18.275 -9.478 -41.518 1.00 29.32 ? 199 ARG A NH1 1 ATOM 1638 N NH2 . ARG A 1 199 ? -20.007 -10.541 -40.437 1.00 36.25 ? 199 ARG A NH2 1 ATOM 1639 N N . ASP A 1 200 ? -12.462 -7.948 -37.997 1.00 21.55 ? 200 ASP A N 1 ATOM 1640 C CA . ASP A 1 200 ? -11.093 -7.462 -38.134 1.00 21.78 ? 200 ASP A CA 1 ATOM 1641 C C . ASP A 1 200 ? -10.471 -7.120 -36.769 1.00 21.26 ? 200 ASP A C 1 ATOM 1642 O O . ASP A 1 200 ? -9.272 -7.284 -36.582 1.00 20.57 ? 200 ASP A O 1 ATOM 1643 C CB . ASP A 1 200 ? -11.044 -6.198 -39.011 1.00 21.70 ? 200 ASP A CB 1 ATOM 1644 C CG . ASP A 1 200 ? -11.093 -6.499 -40.541 1.00 25.98 ? 200 ASP A CG 1 ATOM 1645 O OD1 . ASP A 1 200 ? -10.975 -7.670 -40.960 1.00 27.08 ? 200 ASP A OD1 1 ATOM 1646 O OD2 . ASP A 1 200 ? -11.246 -5.531 -41.323 1.00 27.93 ? 200 ASP A OD2 1 ATOM 1647 N N . TYR A 1 201 ? -11.303 -6.619 -35.854 1.00 21.07 ? 201 TYR A N 1 ATOM 1648 C CA . TYR A 1 201 ? -10.885 -6.272 -34.485 1.00 20.73 ? 201 TYR A CA 1 ATOM 1649 C C . TYR A 1 201 ? -10.448 -7.512 -33.679 1.00 21.00 ? 201 TYR A C 1 ATOM 1650 O O . TYR A 1 201 ? -9.317 -7.570 -33.151 1.00 20.63 ? 201 TYR A O 1 ATOM 1651 C CB . TYR A 1 201 ? -12.012 -5.488 -33.765 1.00 20.74 ? 201 TYR A CB 1 ATOM 1652 C CG . TYR A 1 201 ? -11.620 -5.022 -32.357 1.00 20.55 ? 201 TYR A CG 1 ATOM 1653 C CD1 . TYR A 1 201 ? -11.702 -5.892 -31.265 1.00 18.27 ? 201 TYR A CD1 1 ATOM 1654 C CD2 . TYR A 1 201 ? -11.158 -3.719 -32.134 1.00 18.38 ? 201 TYR A CD2 1 ATOM 1655 C CE1 . TYR A 1 201 ? -11.302 -5.484 -29.959 1.00 20.78 ? 201 TYR A CE1 1 ATOM 1656 C CE2 . TYR A 1 201 ? -10.781 -3.279 -30.818 1.00 18.16 ? 201 TYR A CE2 1 ATOM 1657 C CZ . TYR A 1 201 ? -10.847 -4.170 -29.748 1.00 20.61 ? 201 TYR A CZ 1 ATOM 1658 O OH . TYR A 1 201 ? -10.448 -3.760 -28.463 1.00 20.21 ? 201 TYR A OH 1 ATOM 1659 N N . VAL A 1 202 ? -11.338 -8.499 -33.593 1.00 20.97 ? 202 VAL A N 1 ATOM 1660 C CA . VAL A 1 202 ? -11.059 -9.780 -32.942 1.00 20.88 ? 202 VAL A CA 1 ATOM 1661 C C . VAL A 1 202 ? -9.738 -10.400 -33.481 1.00 21.11 ? 202 VAL A C 1 ATOM 1662 O O . VAL A 1 202 ? -8.840 -10.806 -32.700 1.00 20.09 ? 202 VAL A O 1 ATOM 1663 C CB . VAL A 1 202 ? -12.281 -10.747 -33.127 1.00 21.01 ? 202 VAL A CB 1 ATOM 1664 C CG1 . VAL A 1 202 ? -11.991 -12.142 -32.605 1.00 22.40 ? 202 VAL A CG1 1 ATOM 1665 C CG2 . VAL A 1 202 ? -13.535 -10.186 -32.439 1.00 22.13 ? 202 VAL A CG2 1 ATOM 1666 N N . PHE A 1 203 ? -9.614 -10.468 -34.810 1.00 20.63 ? 203 PHE A N 1 ATOM 1667 C CA . PHE A 1 203 ? -8.377 -10.968 -35.442 1.00 20.89 ? 203 PHE A CA 1 ATOM 1668 C C . PHE A 1 203 ? -7.112 -10.178 -35.033 1.00 20.41 ? 203 PHE A C 1 ATOM 1669 O O . PHE A 1 203 ? -6.062 -10.756 -34.736 1.00 20.10 ? 203 PHE A O 1 ATOM 1670 C CB . PHE A 1 203 ? -8.520 -10.996 -36.978 1.00 21.06 ? 203 PHE A CB 1 ATOM 1671 C CG . PHE A 1 203 ? -7.472 -11.833 -37.671 1.00 22.47 ? 203 PHE A CG 1 ATOM 1672 C CD1 . PHE A 1 203 ? -6.278 -11.257 -38.104 1.00 24.60 ? 203 PHE A CD1 1 ATOM 1673 C CD2 . PHE A 1 203 ? -7.684 -13.195 -37.886 1.00 23.11 ? 203 PHE A CD2 1 ATOM 1674 C CE1 . PHE A 1 203 ? -5.286 -12.042 -38.766 1.00 26.88 ? 203 PHE A CE1 1 ATOM 1675 C CE2 . PHE A 1 203 ? -6.713 -14.003 -38.538 1.00 23.98 ? 203 PHE A CE2 1 ATOM 1676 C CZ . PHE A 1 203 ? -5.513 -13.423 -38.977 1.00 25.51 ? 203 PHE A CZ 1 ATOM 1677 N N . ARG A 1 204 ? -7.210 -8.854 -35.020 1.00 21.07 ? 204 ARG A N 1 ATOM 1678 C CA . ARG A 1 204 ? -6.052 -8.049 -34.698 1.00 21.73 ? 204 ARG A CA 1 ATOM 1679 C C . ARG A 1 204 ? -5.644 -8.182 -33.222 1.00 21.64 ? 204 ARG A C 1 ATOM 1680 O O . ARG A 1 204 ? -4.459 -8.099 -32.901 1.00 20.84 ? 204 ARG A O 1 ATOM 1681 C CB . ARG A 1 204 ? -6.291 -6.586 -35.062 1.00 21.96 ? 204 ARG A CB 1 ATOM 1682 C CG . ARG A 1 204 ? -5.013 -5.813 -35.207 1.00 25.99 ? 204 ARG A CG 1 ATOM 1683 C CD . ARG A 1 204 ? -5.254 -4.389 -35.542 1.00 27.17 ? 204 ARG A CD 1 ATOM 1684 N NE . ARG A 1 204 ? -4.029 -3.604 -35.424 1.00 30.81 ? 204 ARG A NE 1 ATOM 1685 C CZ . ARG A 1 204 ? -3.187 -3.355 -36.431 1.00 33.56 ? 204 ARG A CZ 1 ATOM 1686 N NH1 . ARG A 1 204 ? -3.403 -3.847 -37.648 1.00 32.13 ? 204 ARG A NH1 1 ATOM 1687 N NH2 . ARG A 1 204 ? -2.113 -2.618 -36.221 1.00 34.99 ? 204 ARG A NH2 1 ATOM 1688 N N . SER A 1 205 ? -6.617 -8.362 -32.326 1.00 22.01 ? 205 SER A N 1 ATOM 1689 C CA . SER A 1 205 ? -6.297 -8.550 -30.904 1.00 22.50 ? 205 SER A CA 1 ATOM 1690 C C . SER A 1 205 ? -5.501 -9.859 -30.704 1.00 22.29 ? 205 SER A C 1 ATOM 1691 O O . SER A 1 205 ? -4.569 -9.932 -29.900 1.00 21.74 ? 205 SER A O 1 ATOM 1692 C CB . SER A 1 205 ? -7.563 -8.534 -30.046 1.00 22.40 ? 205 SER A CB 1 ATOM 1693 O OG . SER A 1 205 ? -8.287 -9.754 -30.181 1.00 24.16 ? 205 SER A OG 1 ATOM 1694 N N . MET A 1 206 ? -5.853 -10.880 -31.460 1.00 21.69 ? 206 MET A N 1 ATOM 1695 C CA . MET A 1 206 ? -5.040 -12.087 -31.447 1.00 22.71 ? 206 MET A CA 1 ATOM 1696 C C . MET A 1 206 ? -3.657 -11.833 -32.049 1.00 22.19 ? 206 MET A C 1 ATOM 1697 O O . MET A 1 206 ? -2.694 -12.360 -31.533 1.00 22.64 ? 206 MET A O 1 ATOM 1698 C CB . MET A 1 206 ? -5.733 -13.257 -32.139 1.00 22.65 ? 206 MET A CB 1 ATOM 1699 C CG . MET A 1 206 ? -6.810 -13.900 -31.247 1.00 23.98 ? 206 MET A CG 1 ATOM 1700 S SD . MET A 1 206 ? -7.785 -15.127 -32.141 1.00 24.49 ? 206 MET A SD 1 ATOM 1701 C CE . MET A 1 206 ? -8.329 -14.157 -33.536 1.00 21.94 ? 206 MET A CE 1 ATOM 1702 N N . GLN A 1 207 ? -3.564 -11.022 -33.108 1.00 22.31 ? 207 GLN A N 1 ATOM 1703 C CA . GLN A 1 207 ? -2.265 -10.711 -33.701 1.00 23.07 ? 207 GLN A CA 1 ATOM 1704 C C . GLN A 1 207 ? -1.378 -10.020 -32.676 1.00 22.92 ? 207 GLN A C 1 ATOM 1705 O O . GLN A 1 207 ? -0.203 -10.365 -32.552 1.00 22.29 ? 207 GLN A O 1 ATOM 1706 C CB . GLN A 1 207 ? -2.387 -9.783 -34.910 1.00 23.12 ? 207 GLN A CB 1 ATOM 1707 C CG . GLN A 1 207 ? -2.761 -10.479 -36.220 1.00 27.26 ? 207 GLN A CG 1 ATOM 1708 C CD . GLN A 1 207 ? -2.980 -9.479 -37.340 1.00 29.82 ? 207 GLN A CD 1 ATOM 1709 O OE1 . GLN A 1 207 ? -3.830 -8.601 -37.247 1.00 31.18 ? 207 GLN A OE1 1 ATOM 1710 N NE2 . GLN A 1 207 ? -2.216 -9.613 -38.400 1.00 32.20 ? 207 GLN A NE2 1 ATOM 1711 N N . GLU A 1 208 ? -1.938 -9.025 -31.983 1.00 22.75 ? 208 GLU A N 1 ATOM 1712 C CA . GLU A 1 208 ? -1.178 -8.264 -30.972 1.00 23.76 ? 208 GLU A CA 1 ATOM 1713 C C . GLU A 1 208 ? -0.684 -9.109 -29.782 1.00 22.53 ? 208 GLU A C 1 ATOM 1714 O O . GLU A 1 208 ? 0.482 -9.015 -29.390 1.00 22.83 ? 208 GLU A O 1 ATOM 1715 C CB . GLU A 1 208 ? -1.937 -7.007 -30.536 1.00 23.48 ? 208 GLU A CB 1 ATOM 1716 C CG . GLU A 1 208 ? -1.660 -5.802 -31.487 1.00 28.24 ? 208 GLU A CG 1 ATOM 1717 C CD . GLU A 1 208 ? -2.583 -4.604 -31.287 1.00 31.94 ? 208 GLU A CD 1 ATOM 1718 O OE1 . GLU A 1 208 ? -3.041 -4.351 -30.159 1.00 36.33 ? 208 GLU A OE1 1 ATOM 1719 O OE2 . GLU A 1 208 ? -2.857 -3.900 -32.279 1.00 35.31 ? 208 GLU A OE2 1 ATOM 1720 N N . PHE A 1 209 ? -1.531 -9.972 -29.238 1.00 21.75 ? 209 PHE A N 1 ATOM 1721 C CA . PHE A 1 209 ? -1.065 -10.850 -28.150 1.00 20.53 ? 209 PHE A CA 1 ATOM 1722 C C . PHE A 1 209 ? -0.036 -11.897 -28.629 1.00 20.73 ? 209 PHE A C 1 ATOM 1723 O O . PHE A 1 209 ? 0.973 -12.151 -27.956 1.00 18.82 ? 209 PHE A O 1 ATOM 1724 C CB . PHE A 1 209 ? -2.243 -11.441 -27.383 1.00 20.68 ? 209 PHE A CB 1 ATOM 1725 C CG . PHE A 1 209 ? -2.830 -10.480 -26.374 1.00 19.84 ? 209 PHE A CG 1 ATOM 1726 C CD1 . PHE A 1 209 ? -2.549 -10.631 -25.015 1.00 20.53 ? 209 PHE A CD1 1 ATOM 1727 C CD2 . PHE A 1 209 ? -3.609 -9.397 -26.785 1.00 17.78 ? 209 PHE A CD2 1 ATOM 1728 C CE1 . PHE A 1 209 ? -3.056 -9.739 -24.075 1.00 20.07 ? 209 PHE A CE1 1 ATOM 1729 C CE2 . PHE A 1 209 ? -4.126 -8.482 -25.842 1.00 18.64 ? 209 PHE A CE2 1 ATOM 1730 C CZ . PHE A 1 209 ? -3.849 -8.648 -24.497 1.00 18.23 ? 209 PHE A CZ 1 ATOM 1731 N N . TYR A 1 210 ? -0.273 -12.451 -29.820 1.00 21.31 ? 210 TYR A N 1 ATOM 1732 C CA . TYR A 1 210 ? 0.631 -13.436 -30.394 1.00 21.63 ? 210 TYR A CA 1 ATOM 1733 C C . TYR A 1 210 ? 2.028 -12.833 -30.523 1.00 21.22 ? 210 TYR A C 1 ATOM 1734 O O . TYR A 1 210 ? 2.998 -13.442 -30.122 1.00 20.77 ? 210 TYR A O 1 ATOM 1735 C CB . TYR A 1 210 ? 0.108 -13.951 -31.756 1.00 21.67 ? 210 TYR A CB 1 ATOM 1736 C CG . TYR A 1 210 ? 0.990 -15.031 -32.351 1.00 23.05 ? 210 TYR A CG 1 ATOM 1737 C CD1 . TYR A 1 210 ? 0.936 -16.354 -31.868 1.00 24.58 ? 210 TYR A CD1 1 ATOM 1738 C CD2 . TYR A 1 210 ? 1.910 -14.738 -33.358 1.00 24.00 ? 210 TYR A CD2 1 ATOM 1739 C CE1 . TYR A 1 210 ? 1.750 -17.338 -32.387 1.00 24.30 ? 210 TYR A CE1 1 ATOM 1740 C CE2 . TYR A 1 210 ? 2.734 -15.741 -33.894 1.00 24.52 ? 210 TYR A CE2 1 ATOM 1741 C CZ . TYR A 1 210 ? 2.651 -17.026 -33.394 1.00 25.36 ? 210 TYR A CZ 1 ATOM 1742 O OH . TYR A 1 210 ? 3.459 -18.028 -33.897 1.00 28.98 ? 210 TYR A OH 1 ATOM 1743 N N . GLU A 1 211 ? 2.096 -11.625 -31.075 1.00 22.48 ? 211 GLU A N 1 ATOM 1744 C CA . GLU A 1 211 ? 3.328 -10.868 -31.261 1.00 23.41 ? 211 GLU A CA 1 ATOM 1745 C C . GLU A 1 211 ? 4.072 -10.647 -29.925 1.00 23.72 ? 211 GLU A C 1 ATOM 1746 O O . GLU A 1 211 ? 5.325 -10.643 -29.876 1.00 22.51 ? 211 GLU A O 1 ATOM 1747 C CB . GLU A 1 211 ? 2.966 -9.540 -31.934 1.00 24.42 ? 211 GLU A CB 1 ATOM 1748 C CG . GLU A 1 211 ? 4.126 -8.772 -32.557 1.00 29.14 ? 211 GLU A CG 1 ATOM 1749 C CD . GLU A 1 211 ? 4.828 -7.855 -31.564 1.00 37.50 ? 211 GLU A CD 1 ATOM 1750 O OE1 . GLU A 1 211 ? 4.208 -7.493 -30.529 1.00 40.92 ? 211 GLU A OE1 1 ATOM 1751 O OE2 . GLU A 1 211 ? 6.005 -7.488 -31.807 1.00 39.42 ? 211 GLU A OE2 1 ATOM 1752 N N . ASP A 1 212 ? 3.293 -10.494 -28.844 1.00 22.58 ? 212 ASP A N 1 ATOM 1753 C CA . ASP A 1 212 ? 3.834 -10.306 -27.499 1.00 22.24 ? 212 ASP A CA 1 ATOM 1754 C C . ASP A 1 212 ? 4.123 -11.673 -26.852 1.00 21.20 ? 212 ASP A C 1 ATOM 1755 O O . ASP A 1 212 ? 4.328 -11.753 -25.646 1.00 21.21 ? 212 ASP A O 1 ATOM 1756 C CB . ASP A 1 212 ? 2.826 -9.490 -26.652 1.00 22.46 ? 212 ASP A CB 1 ATOM 1757 C CG . ASP A 1 212 ? 3.446 -8.858 -25.384 1.00 23.69 ? 212 ASP A CG 1 ATOM 1758 O OD1 . ASP A 1 212 ? 4.565 -8.305 -25.456 1.00 26.79 ? 212 ASP A OD1 1 ATOM 1759 O OD2 . ASP A 1 212 ? 2.795 -8.921 -24.304 1.00 21.55 ? 212 ASP A OD2 1 ATOM 1760 N N . ASN A 1 213 ? 4.152 -12.746 -27.648 1.00 20.62 ? 213 ASN A N 1 ATOM 1761 C CA . ASN A 1 213 ? 4.437 -14.132 -27.153 1.00 20.32 ? 213 ASN A CA 1 ATOM 1762 C C . ASN A 1 213 ? 3.397 -14.636 -26.112 1.00 20.33 ? 213 ASN A C 1 ATOM 1763 O O . ASN A 1 213 ? 3.744 -15.307 -25.121 1.00 20.16 ? 213 ASN A O 1 ATOM 1764 C CB . ASN A 1 213 ? 5.901 -14.294 -26.641 1.00 20.75 ? 213 ASN A CB 1 ATOM 1765 C CG . ASN A 1 213 ? 6.453 -15.762 -26.778 1.00 22.97 ? 213 ASN A CG 1 ATOM 1766 O OD1 . ASN A 1 213 ? 5.709 -16.725 -27.034 1.00 25.31 ? 213 ASN A OD1 1 ATOM 1767 N ND2 . ASN A 1 213 ? 7.761 -15.917 -26.574 1.00 23.01 ? 213 ASN A ND2 1 ATOM 1768 N N . VAL A 1 214 ? 2.125 -14.305 -26.364 1.00 19.41 ? 214 VAL A N 1 ATOM 1769 C CA . VAL A 1 214 ? 0.992 -14.808 -25.576 1.00 19.52 ? 214 VAL A CA 1 ATOM 1770 C C . VAL A 1 214 ? 0.143 -15.723 -26.471 1.00 19.18 ? 214 VAL A C 1 ATOM 1771 O O . VAL A 1 214 ? -0.245 -15.326 -27.576 1.00 19.38 ? 214 VAL A O 1 ATOM 1772 C CB . VAL A 1 214 ? 0.128 -13.613 -25.018 1.00 19.70 ? 214 VAL A CB 1 ATOM 1773 C CG1 . VAL A 1 214 ? -1.079 -14.107 -24.185 1.00 20.18 ? 214 VAL A CG1 1 ATOM 1774 C CG2 . VAL A 1 214 ? 1.000 -12.638 -24.201 1.00 19.04 ? 214 VAL A CG2 1 ATOM 1775 N N . LEU A 1 215 ? -0.143 -16.938 -26.007 1.00 18.31 ? 215 LEU A N 1 ATOM 1776 C CA . LEU A 1 215 ? -0.713 -17.962 -26.888 1.00 18.51 ? 215 LEU A CA 1 ATOM 1777 C C . LEU A 1 215 ? -2.188 -18.327 -26.628 1.00 19.04 ? 215 LEU A C 1 ATOM 1778 O O . LEU A 1 215 ? -2.734 -19.221 -27.299 1.00 19.21 ? 215 LEU A O 1 ATOM 1779 C CB . LEU A 1 215 ? 0.141 -19.244 -26.853 1.00 18.88 ? 215 LEU A CB 1 ATOM 1780 C CG . LEU A 1 215 ? 1.632 -19.145 -27.245 1.00 18.92 ? 215 LEU A CG 1 ATOM 1781 C CD1 . LEU A 1 215 ? 2.320 -20.503 -27.162 1.00 19.79 ? 215 LEU A CD1 1 ATOM 1782 C CD2 . LEU A 1 215 ? 1.788 -18.598 -28.634 1.00 20.22 ? 215 LEU A CD2 1 ATOM 1783 N N . TYR A 1 216 ? -2.825 -17.681 -25.651 1.00 18.35 ? 216 TYR A N 1 ATOM 1784 C CA . TYR A 1 216 ? -4.208 -18.029 -25.292 1.00 17.77 ? 216 TYR A CA 1 ATOM 1785 C C . TYR A 1 216 ? -4.832 -16.827 -24.591 1.00 18.37 ? 216 TYR A C 1 ATOM 1786 O O . TYR A 1 216 ? -4.151 -16.199 -23.782 1.00 18.23 ? 216 TYR A O 1 ATOM 1787 C CB . TYR A 1 216 ? -4.225 -19.271 -24.384 1.00 17.94 ? 216 TYR A CB 1 ATOM 1788 C CG . TYR A 1 216 ? -5.601 -19.677 -23.865 1.00 17.36 ? 216 TYR A CG 1 ATOM 1789 C CD1 . TYR A 1 216 ? -6.580 -20.153 -24.731 1.00 16.83 ? 216 TYR A CD1 1 ATOM 1790 C CD2 . TYR A 1 216 ? -5.907 -19.603 -22.515 1.00 18.91 ? 216 TYR A CD2 1 ATOM 1791 C CE1 . TYR A 1 216 ? -7.858 -20.510 -24.268 1.00 16.31 ? 216 TYR A CE1 1 ATOM 1792 C CE2 . TYR A 1 216 ? -7.189 -19.969 -22.033 1.00 18.80 ? 216 TYR A CE2 1 ATOM 1793 C CZ . TYR A 1 216 ? -8.141 -20.424 -22.921 1.00 17.39 ? 216 TYR A CZ 1 ATOM 1794 O OH . TYR A 1 216 ? -9.394 -20.786 -22.466 1.00 20.77 ? 216 TYR A OH 1 ATOM 1795 N N . MET A 1 217 ? -6.094 -16.495 -24.923 1.00 18.44 ? 217 MET A N 1 ATOM 1796 C CA . MET A 1 217 ? -6.836 -15.375 -24.296 1.00 18.38 ? 217 MET A CA 1 ATOM 1797 C C . MET A 1 217 ? -8.199 -15.825 -23.766 1.00 17.21 ? 217 MET A C 1 ATOM 1798 O O . MET A 1 217 ? -8.926 -16.504 -24.468 1.00 17.54 ? 217 MET A O 1 ATOM 1799 C CB . MET A 1 217 ? -7.070 -14.223 -25.297 1.00 18.11 ? 217 MET A CB 1 ATOM 1800 C CG . MET A 1 217 ? -5.790 -13.579 -25.859 1.00 21.34 ? 217 MET A CG 1 ATOM 1801 S SD . MET A 1 217 ? -5.941 -12.841 -27.493 1.00 24.71 ? 217 MET A SD 1 ATOM 1802 C CE . MET A 1 217 ? -6.829 -11.312 -27.179 1.00 25.18 ? 217 MET A CE 1 ATOM 1803 N N . GLU A 1 218 ? -8.559 -15.432 -22.551 1.00 17.29 ? 218 GLU A N 1 ATOM 1804 C CA . GLU A 1 218 ? -9.971 -15.504 -22.115 1.00 16.70 ? 218 GLU A CA 1 ATOM 1805 C C . GLU A 1 218 ? -10.453 -14.059 -21.923 1.00 17.80 ? 218 GLU A C 1 ATOM 1806 O O . GLU A 1 218 ? -9.785 -13.240 -21.248 1.00 17.51 ? 218 GLU A O 1 ATOM 1807 C CB . GLU A 1 218 ? -10.157 -16.356 -20.836 1.00 17.18 ? 218 GLU A CB 1 ATOM 1808 C CG . GLU A 1 218 ? -9.812 -17.865 -21.071 1.00 16.60 ? 218 GLU A CG 1 ATOM 1809 C CD . GLU A 1 218 ? -9.963 -18.779 -19.849 1.00 19.06 ? 218 GLU A CD 1 ATOM 1810 O OE1 . GLU A 1 218 ? -10.173 -18.286 -18.714 1.00 17.21 ? 218 GLU A OE1 1 ATOM 1811 O OE2 . GLU A 1 218 ? -9.877 -20.027 -20.030 1.00 18.75 ? 218 GLU A OE2 1 ATOM 1812 N N . ILE A 1 219 ? -11.612 -13.762 -22.506 1.00 17.76 ? 219 ILE A N 1 ATOM 1813 C CA . ILE A 1 219 ? -12.080 -12.400 -22.677 1.00 17.28 ? 219 ILE A CA 1 ATOM 1814 C C . ILE A 1 219 ? -13.453 -12.236 -22.010 1.00 17.87 ? 219 ILE A C 1 ATOM 1815 O O . ILE A 1 219 ? -14.371 -13.008 -22.308 1.00 17.46 ? 219 ILE A O 1 ATOM 1816 C CB . ILE A 1 219 ? -12.175 -12.071 -24.192 1.00 17.68 ? 219 ILE A CB 1 ATOM 1817 C CG1 . ILE A 1 219 ? -10.836 -12.342 -24.910 1.00 16.65 ? 219 ILE A CG1 1 ATOM 1818 C CG2 . ILE A 1 219 ? -12.609 -10.631 -24.420 1.00 18.21 ? 219 ILE A CG2 1 ATOM 1819 C CD1 . ILE A 1 219 ? -10.881 -12.254 -26.448 1.00 21.32 ? 219 ILE A CD1 1 ATOM 1820 N N . ARG A 1 220 ? -13.591 -11.257 -21.103 1.00 17.50 ? 220 ARG A N 1 ATOM 1821 C CA . ARG A 1 220 ? -14.918 -10.816 -20.628 1.00 18.40 ? 220 ARG A CA 1 ATOM 1822 C C . ARG A 1 220 ? -15.576 -10.009 -21.737 1.00 18.83 ? 220 ARG A C 1 ATOM 1823 O O . ARG A 1 220 ? -15.053 -8.977 -22.156 1.00 19.57 ? 220 ARG A O 1 ATOM 1824 C CB . ARG A 1 220 ? -14.825 -9.931 -19.376 1.00 18.37 ? 220 ARG A CB 1 ATOM 1825 C CG . ARG A 1 220 ? -14.956 -10.663 -18.028 1.00 21.57 ? 220 ARG A CG 1 ATOM 1826 C CD . ARG A 1 220 ? -13.683 -11.398 -17.653 1.00 19.59 ? 220 ARG A CD 1 ATOM 1827 N NE . ARG A 1 220 ? -13.604 -11.658 -16.215 1.00 19.91 ? 220 ARG A NE 1 ATOM 1828 C CZ . ARG A 1 220 ? -12.558 -12.207 -15.618 1.00 19.71 ? 220 ARG A CZ 1 ATOM 1829 N NH1 . ARG A 1 220 ? -11.522 -12.584 -16.352 1.00 17.34 ? 220 ARG A NH1 1 ATOM 1830 N NH2 . ARG A 1 220 ? -12.553 -12.387 -14.296 1.00 18.12 ? 220 ARG A NH2 1 ATOM 1831 N N . ALA A 1 221 ? -16.710 -10.495 -22.226 1.00 18.67 ? 221 ALA A N 1 ATOM 1832 C CA . ALA A 1 221 ? -17.343 -9.905 -23.387 1.00 18.37 ? 221 ALA A CA 1 ATOM 1833 C C . ALA A 1 221 ? -18.771 -9.566 -23.042 1.00 18.92 ? 221 ALA A C 1 ATOM 1834 O O . ALA A 1 221 ? -19.505 -10.423 -22.578 1.00 19.18 ? 221 ALA A O 1 ATOM 1835 C CB . ALA A 1 221 ? -17.300 -10.882 -24.545 1.00 17.79 ? 221 ALA A CB 1 ATOM 1836 N N . ARG A 1 222 ? -19.162 -8.312 -23.270 1.00 19.41 ? 222 ARG A N 1 ATOM 1837 C CA . ARG A 1 222 ? -20.554 -7.878 -23.068 1.00 20.76 ? 222 ARG A CA 1 ATOM 1838 C C . ARG A 1 222 ? -21.490 -8.422 -24.170 1.00 21.22 ? 222 ARG A C 1 ATOM 1839 O O . ARG A 1 222 ? -22.711 -8.476 -23.992 1.00 20.76 ? 222 ARG A O 1 ATOM 1840 C CB . ARG A 1 222 ? -20.632 -6.351 -23.054 1.00 19.73 ? 222 ARG A CB 1 ATOM 1841 C CG . ARG A 1 222 ? -19.911 -5.669 -21.887 1.00 23.40 ? 222 ARG A CG 1 ATOM 1842 C CD . ARG A 1 222 ? -20.645 -5.820 -20.569 1.00 23.15 ? 222 ARG A CD 1 ATOM 1843 N NE . ARG A 1 222 ? -22.051 -5.427 -20.679 1.00 29.31 ? 222 ARG A NE 1 ATOM 1844 C CZ . ARG A 1 222 ? -22.507 -4.176 -20.620 1.00 29.68 ? 222 ARG A CZ 1 ATOM 1845 N NH1 . ARG A 1 222 ? -21.680 -3.154 -20.447 1.00 29.98 ? 222 ARG A NH1 1 ATOM 1846 N NH2 . ARG A 1 222 ? -23.804 -3.954 -20.728 1.00 30.80 ? 222 ARG A NH2 1 ATOM 1847 N N . LEU A 1 223 ? -20.892 -8.829 -25.294 1.00 21.97 ? 223 LEU A N 1 ATOM 1848 C CA . LEU A 1 223 ? -21.643 -9.299 -26.467 1.00 23.50 ? 223 LEU A CA 1 ATOM 1849 C C . LEU A 1 223 ? -22.787 -8.333 -26.825 1.00 23.55 ? 223 LEU A C 1 ATOM 1850 O O . LEU A 1 223 ? -23.940 -8.734 -26.947 1.00 24.20 ? 223 LEU A O 1 ATOM 1851 C CB . LEU A 1 223 ? -22.185 -10.726 -26.254 1.00 23.34 ? 223 LEU A CB 1 ATOM 1852 C CG . LEU A 1 223 ? -21.158 -11.820 -25.899 1.00 23.86 ? 223 LEU A CG 1 ATOM 1853 C CD1 . LEU A 1 223 ? -21.879 -13.101 -25.502 1.00 24.32 ? 223 LEU A CD1 1 ATOM 1854 C CD2 . LEU A 1 223 ? -20.176 -12.061 -27.041 1.00 22.24 ? 223 LEU A CD2 1 ATOM 1855 N N . LEU A 1 224 ? -22.458 -7.065 -27.008 1.00 24.71 ? 224 LEU A N 1 ATOM 1856 C CA . LEU A 1 224 ? -23.470 -6.100 -27.374 1.00 25.13 ? 224 LEU A CA 1 ATOM 1857 C C . LEU A 1 224 ? -23.760 -6.300 -28.868 1.00 25.33 ? 224 LEU A C 1 ATOM 1858 O O . LEU A 1 224 ? -22.958 -6.953 -29.567 1.00 24.51 ? 224 LEU A O 1 ATOM 1859 C CB . LEU A 1 224 ? -23.044 -4.676 -27.011 1.00 26.33 ? 224 LEU A CB 1 ATOM 1860 C CG . LEU A 1 224 ? -22.718 -4.395 -25.536 1.00 27.23 ? 224 LEU A CG 1 ATOM 1861 C CD1 . LEU A 1 224 ? -22.195 -2.965 -25.354 1.00 30.64 ? 224 LEU A CD1 1 ATOM 1862 C CD2 . LEU A 1 224 ? -23.891 -4.646 -24.604 1.00 29.99 ? 224 LEU A CD2 1 ATOM 1863 N N . PRO A 1 225 ? -24.929 -5.809 -29.346 1.00 24.92 ? 225 PRO A N 1 ATOM 1864 C CA . PRO A 1 225 ? -25.335 -6.106 -30.729 1.00 24.72 ? 225 PRO A CA 1 ATOM 1865 C C . PRO A 1 225 ? -24.342 -5.626 -31.768 1.00 24.77 ? 225 PRO A C 1 ATOM 1866 O O . PRO A 1 225 ? -23.904 -4.470 -31.731 1.00 25.22 ? 225 PRO A O 1 ATOM 1867 C CB . PRO A 1 225 ? -26.709 -5.411 -30.880 1.00 25.01 ? 225 PRO A CB 1 ATOM 1868 C CG . PRO A 1 225 ? -26.949 -4.643 -29.584 1.00 26.13 ? 225 PRO A CG 1 ATOM 1869 C CD . PRO A 1 225 ? -26.061 -5.318 -28.539 1.00 25.04 ? 225 PRO A CD 1 ATOM 1870 N N . VAL A 1 226 ? -23.949 -6.535 -32.656 1.00 24.23 ? 226 VAL A N 1 ATOM 1871 C CA . VAL A 1 226 ? -23.106 -6.209 -33.782 1.00 23.77 ? 226 VAL A CA 1 ATOM 1872 C C . VAL A 1 226 ? -24.086 -5.935 -34.929 1.00 24.82 ? 226 VAL A C 1 ATOM 1873 O O . VAL A 1 226 ? -25.057 -6.675 -35.075 1.00 24.07 ? 226 VAL A O 1 ATOM 1874 C CB . VAL A 1 226 ? -22.153 -7.385 -34.099 1.00 24.03 ? 226 VAL A CB 1 ATOM 1875 C CG1 . VAL A 1 226 ? -21.386 -7.139 -35.399 1.00 23.45 ? 226 VAL A CG1 1 ATOM 1876 C CG2 . VAL A 1 226 ? -21.165 -7.619 -32.914 1.00 21.80 ? 226 VAL A CG2 1 ATOM 1877 N N . TYR A 1 227 ? -23.844 -4.861 -35.694 1.00 25.03 ? 227 TYR A N 1 ATOM 1878 C CA . TYR A 1 227 ? -24.773 -4.357 -36.711 1.00 25.91 ? 227 TYR A CA 1 ATOM 1879 C C . TYR A 1 227 ? -24.229 -4.370 -38.153 1.00 26.84 ? 227 TYR A C 1 ATOM 1880 O O . TYR A 1 227 ? -23.017 -4.417 -38.376 1.00 26.82 ? 227 TYR A O 1 ATOM 1881 C CB . TYR A 1 227 ? -25.309 -2.966 -36.326 1.00 25.88 ? 227 TYR A CB 1 ATOM 1882 C CG . TYR A 1 227 ? -24.301 -1.838 -36.401 1.00 26.27 ? 227 TYR A CG 1 ATOM 1883 C CD1 . TYR A 1 227 ? -24.168 -1.068 -37.560 1.00 27.28 ? 227 TYR A CD1 1 ATOM 1884 C CD2 . TYR A 1 227 ? -23.475 -1.532 -35.308 1.00 27.18 ? 227 TYR A CD2 1 ATOM 1885 C CE1 . TYR A 1 227 ? -23.234 -0.022 -37.640 1.00 26.46 ? 227 TYR A CE1 1 ATOM 1886 C CE2 . TYR A 1 227 ? -22.537 -0.483 -35.377 1.00 27.58 ? 227 TYR A CE2 1 ATOM 1887 C CZ . TYR A 1 227 ? -22.425 0.270 -36.544 1.00 25.48 ? 227 TYR A CZ 1 ATOM 1888 O OH . TYR A 1 227 ? -21.502 1.306 -36.635 1.00 24.12 ? 227 TYR A OH 1 ATOM 1889 N N . GLU A 1 228 ? -25.135 -4.352 -39.133 1.00 27.78 ? 228 GLU A N 1 ATOM 1890 C CA . GLU A 1 228 ? -24.764 -4.302 -40.562 1.00 29.07 ? 228 GLU A CA 1 ATOM 1891 C C . GLU A 1 228 ? -25.158 -2.954 -41.181 1.00 29.86 ? 228 GLU A C 1 ATOM 1892 O O . GLU A 1 228 ? -25.967 -2.246 -40.611 1.00 30.44 ? 228 GLU A O 1 ATOM 1893 C CB . GLU A 1 228 ? -25.470 -5.425 -41.341 1.00 29.33 ? 228 GLU A CB 1 ATOM 1894 C CG . GLU A 1 228 ? -25.255 -6.842 -40.800 1.00 28.60 ? 228 GLU A CG 1 ATOM 1895 C CD . GLU A 1 228 ? -23.922 -7.431 -41.185 1.00 28.71 ? 228 GLU A CD 1 ATOM 1896 O OE1 . GLU A 1 228 ? -23.214 -6.857 -42.037 1.00 30.52 ? 228 GLU A OE1 1 ATOM 1897 O OE2 . GLU A 1 228 ? -23.566 -8.490 -40.634 1.00 30.98 ? 228 GLU A OE2 1 ATOM 1898 N N . LEU A 1 229 ? -24.605 -2.618 -42.348 1.00 31.65 ? 229 LEU A N 1 ATOM 1899 C CA . LEU A 1 229 ? -24.984 -1.392 -43.084 1.00 33.55 ? 229 LEU A CA 1 ATOM 1900 C C . LEU A 1 229 ? -26.479 -1.367 -43.360 1.00 34.90 ? 229 LEU A C 1 ATOM 1901 O O . LEU A 1 229 ? -27.118 -0.312 -43.351 1.00 35.41 ? 229 LEU A O 1 ATOM 1902 C CB . LEU A 1 229 ? -24.273 -1.312 -44.429 1.00 33.15 ? 229 LEU A CB 1 ATOM 1903 C CG . LEU A 1 229 ? -22.945 -0.596 -44.632 1.00 33.55 ? 229 LEU A CG 1 ATOM 1904 C CD1 . LEU A 1 229 ? -22.711 -0.462 -46.125 1.00 32.65 ? 229 LEU A CD1 1 ATOM 1905 C CD2 . LEU A 1 229 ? -22.922 0.785 -43.957 1.00 33.01 ? 229 LEU A CD2 1 ATOM 1906 N N . SER A 1 230 ? -27.022 -2.555 -43.607 1.00 35.72 ? 230 SER A N 1 ATOM 1907 C CA . SER A 1 230 ? -28.432 -2.744 -43.897 1.00 36.27 ? 230 SER A CA 1 ATOM 1908 C C . SER A 1 230 ? -29.311 -2.355 -42.712 1.00 36.92 ? 230 SER A C 1 ATOM 1909 O O . SER A 1 230 ? -30.527 -2.439 -42.799 1.00 37.65 ? 230 SER A O 1 ATOM 1910 C CB . SER A 1 230 ? -28.665 -4.212 -44.273 1.00 36.46 ? 230 SER A CB 1 ATOM 1911 O OG . SER A 1 230 ? -28.427 -5.070 -43.165 1.00 33.51 ? 230 SER A OG 1 ATOM 1912 N N . GLY A 1 231 ? -28.692 -1.940 -41.606 1.00 37.38 ? 231 GLY A N 1 ATOM 1913 C CA . GLY A 1 231 ? -29.429 -1.610 -40.374 1.00 37.33 ? 231 GLY A CA 1 ATOM 1914 C C . GLY A 1 231 ? -29.761 -2.771 -39.439 1.00 37.23 ? 231 GLY A C 1 ATOM 1915 O O . GLY A 1 231 ? -30.086 -2.545 -38.269 1.00 37.84 ? 231 GLY A O 1 ATOM 1916 N N . GLU A 1 232 ? -29.693 -4.007 -39.946 1.00 37.35 ? 232 GLU A N 1 ATOM 1917 C CA . GLU A 1 232 ? -29.869 -5.239 -39.123 1.00 36.81 ? 232 GLU A CA 1 ATOM 1918 C C . GLU A 1 232 ? -28.871 -5.324 -37.945 1.00 35.98 ? 232 GLU A C 1 ATOM 1919 O O . GLU A 1 232 ? -27.717 -4.899 -38.075 1.00 35.39 ? 232 GLU A O 1 ATOM 1920 C CB . GLU A 1 232 ? -29.766 -6.512 -40.003 1.00 36.74 ? 232 GLU A CB 1 ATOM 1921 C CG . GLU A 1 232 ? -28.960 -7.689 -39.354 1.00 39.21 ? 232 GLU A CG 1 ATOM 1922 C CD . GLU A 1 232 ? -29.137 -9.063 -40.022 1.00 42.24 ? 232 GLU A CD 1 ATOM 1923 O OE1 . GLU A 1 232 ? -28.623 -9.268 -41.155 1.00 43.64 ? 232 GLU A OE1 1 ATOM 1924 O OE2 . GLU A 1 232 ? -29.753 -9.955 -39.384 1.00 43.52 ? 232 GLU A OE2 1 ATOM 1925 N N . HIS A 1 233 ? -29.327 -5.889 -36.822 1.00 34.99 ? 233 HIS A N 1 ATOM 1926 C CA . HIS A 1 233 ? -28.481 -6.177 -35.662 1.00 35.16 ? 233 HIS A CA 1 ATOM 1927 C C . HIS A 1 233 ? -28.459 -7.680 -35.382 1.00 33.45 ? 233 HIS A C 1 ATOM 1928 O O . HIS A 1 233 ? -29.489 -8.342 -35.485 1.00 33.02 ? 233 HIS A O 1 ATOM 1929 C CB . HIS A 1 233 ? -28.994 -5.433 -34.425 1.00 35.94 ? 233 HIS A CB 1 ATOM 1930 C CG . HIS A 1 233 ? -28.725 -3.959 -34.445 1.00 40.15 ? 233 HIS A CG 1 ATOM 1931 N ND1 . HIS A 1 233 ? -28.241 -3.274 -33.347 1.00 43.84 ? 233 HIS A ND1 1 ATOM 1932 C CD2 . HIS A 1 233 ? -28.884 -3.032 -35.425 1.00 43.52 ? 233 HIS A CD2 1 ATOM 1933 C CE1 . HIS A 1 233 ? -28.108 -1.993 -33.651 1.00 44.97 ? 233 HIS A CE1 1 ATOM 1934 N NE2 . HIS A 1 233 ? -28.490 -1.820 -34.906 1.00 45.17 ? 233 HIS A NE2 1 ATOM 1935 N N . HIS A 1 234 ? -27.285 -8.212 -35.056 1.00 31.13 ? 234 HIS A N 1 ATOM 1936 C CA . HIS A 1 234 ? -27.155 -9.614 -34.656 1.00 29.81 ? 234 HIS A CA 1 ATOM 1937 C C . HIS A 1 234 ? -27.370 -9.787 -33.146 1.00 28.94 ? 234 HIS A C 1 ATOM 1938 O O . HIS A 1 234 ? -27.502 -8.808 -32.410 1.00 28.48 ? 234 HIS A O 1 ATOM 1939 C CB . HIS A 1 234 ? -25.788 -10.180 -35.059 1.00 29.48 ? 234 HIS A CB 1 ATOM 1940 C CG . HIS A 1 234 ? -25.501 -10.093 -36.525 1.00 29.10 ? 234 HIS A CG 1 ATOM 1941 N ND1 . HIS A 1 234 ? -26.101 -10.918 -37.449 1.00 29.60 ? 234 HIS A ND1 1 ATOM 1942 C CD2 . HIS A 1 234 ? -24.671 -9.286 -37.227 1.00 29.46 ? 234 HIS A CD2 1 ATOM 1943 C CE1 . HIS A 1 234 ? -25.668 -10.615 -38.661 1.00 29.63 ? 234 HIS A CE1 1 ATOM 1944 N NE2 . HIS A 1 234 ? -24.801 -9.625 -38.555 1.00 30.94 ? 234 HIS A NE2 1 ATOM 1945 N N . ASP A 1 235 ? -27.388 -11.036 -32.689 1.00 27.61 ? 235 ASP A N 1 ATOM 1946 C CA . ASP A 1 235 ? -27.593 -11.333 -31.276 1.00 27.18 ? 235 ASP A CA 1 ATOM 1947 C C . ASP A 1 235 ? -26.345 -11.989 -30.610 1.00 26.30 ? 235 ASP A C 1 ATOM 1948 O O . ASP A 1 235 ? -25.276 -12.101 -31.232 1.00 25.21 ? 235 ASP A O 1 ATOM 1949 C CB . ASP A 1 235 ? -28.863 -12.185 -31.092 1.00 27.65 ? 235 ASP A CB 1 ATOM 1950 C CG . ASP A 1 235 ? -28.747 -13.580 -31.709 1.00 29.03 ? 235 ASP A CG 1 ATOM 1951 O OD1 . ASP A 1 235 ? -27.662 -13.952 -32.211 1.00 28.34 ? 235 ASP A OD1 1 ATOM 1952 O OD2 . ASP A 1 235 ? -29.757 -14.325 -31.698 1.00 32.02 ? 235 ASP A OD2 1 ATOM 1953 N N . GLU A 1 236 ? -26.491 -12.397 -29.353 1.00 25.36 ? 236 GLU A N 1 ATOM 1954 C CA . GLU A 1 236 ? -25.366 -12.887 -28.563 1.00 25.55 ? 236 GLU A CA 1 ATOM 1955 C C . GLU A 1 236 ? -24.755 -14.148 -29.174 1.00 25.66 ? 236 GLU A C 1 ATOM 1956 O O . GLU A 1 236 ? -23.530 -14.252 -29.301 1.00 24.93 ? 236 GLU A O 1 ATOM 1957 C CB . GLU A 1 236 ? -25.772 -13.131 -27.100 1.00 25.52 ? 236 GLU A CB 1 ATOM 1958 C CG . GLU A 1 236 ? -26.094 -11.868 -26.301 1.00 25.56 ? 236 GLU A CG 1 ATOM 1959 C CD . GLU A 1 236 ? -27.528 -11.365 -26.484 1.00 29.16 ? 236 GLU A CD 1 ATOM 1960 O OE1 . GLU A 1 236 ? -28.314 -11.959 -27.262 1.00 26.85 ? 236 GLU A OE1 1 ATOM 1961 O OE2 . GLU A 1 236 ? -27.863 -10.349 -25.836 1.00 32.14 ? 236 GLU A OE2 1 ATOM 1962 N N . GLU A 1 237 ? -25.624 -15.087 -29.562 1.00 25.38 ? 237 GLU A N 1 ATOM 1963 C CA . GLU A 1 237 ? -25.207 -16.321 -30.187 1.00 25.84 ? 237 GLU A CA 1 ATOM 1964 C C . GLU A 1 237 ? -24.371 -16.057 -31.437 1.00 24.98 ? 237 GLU A C 1 ATOM 1965 O O . GLU A 1 237 ? -23.311 -16.657 -31.615 1.00 26.06 ? 237 GLU A O 1 ATOM 1966 C CB . GLU A 1 237 ? -26.421 -17.201 -30.493 1.00 26.45 ? 237 GLU A CB 1 ATOM 1967 C CG . GLU A 1 237 ? -26.056 -18.428 -31.305 1.00 31.04 ? 237 GLU A CG 1 ATOM 1968 C CD . GLU A 1 237 ? -27.254 -19.256 -31.733 1.00 35.26 ? 237 GLU A CD 1 ATOM 1969 O OE1 . GLU A 1 237 ? -28.381 -18.978 -31.265 1.00 36.05 ? 237 GLU A OE1 1 ATOM 1970 O OE2 . GLU A 1 237 ? -27.044 -20.202 -32.533 1.00 38.75 ? 237 GLU A OE2 1 ATOM 1971 N N . TRP A 1 238 ? -24.816 -15.136 -32.284 1.00 24.34 ? 238 TRP A N 1 ATOM 1972 C CA . TRP A 1 238 ? -24.041 -14.743 -33.459 1.00 23.99 ? 238 TRP A CA 1 ATOM 1973 C C . TRP A 1 238 ? -22.612 -14.244 -33.091 1.00 22.73 ? 238 TRP A C 1 ATOM 1974 O O . TRP A 1 238 ? -21.628 -14.587 -33.758 1.00 22.33 ? 238 TRP A O 1 ATOM 1975 C CB . TRP A 1 238 ? -24.808 -13.681 -34.256 1.00 24.00 ? 238 TRP A CB 1 ATOM 1976 C CG . TRP A 1 238 ? -24.174 -13.342 -35.553 1.00 27.10 ? 238 TRP A CG 1 ATOM 1977 C CD1 . TRP A 1 238 ? -24.459 -13.891 -36.793 1.00 27.59 ? 238 TRP A CD1 1 ATOM 1978 C CD2 . TRP A 1 238 ? -23.139 -12.364 -35.777 1.00 27.75 ? 238 TRP A CD2 1 ATOM 1979 N NE1 . TRP A 1 238 ? -23.667 -13.309 -37.751 1.00 27.13 ? 238 TRP A NE1 1 ATOM 1980 C CE2 . TRP A 1 238 ? -22.852 -12.372 -37.163 1.00 27.68 ? 238 TRP A CE2 1 ATOM 1981 C CE3 . TRP A 1 238 ? -22.423 -11.486 -34.935 1.00 28.43 ? 238 TRP A CE3 1 ATOM 1982 C CZ2 . TRP A 1 238 ? -21.876 -11.537 -37.732 1.00 28.41 ? 238 TRP A CZ2 1 ATOM 1983 C CZ3 . TRP A 1 238 ? -21.466 -10.653 -35.494 1.00 27.95 ? 238 TRP A CZ3 1 ATOM 1984 C CH2 . TRP A 1 238 ? -21.202 -10.680 -36.889 1.00 28.44 ? 238 TRP A CH2 1 ATOM 1985 N N . SER A 1 239 ? -22.502 -13.455 -32.027 1.00 21.67 ? 239 SER A N 1 ATOM 1986 C CA . SER A 1 239 ? -21.188 -12.899 -31.631 1.00 21.15 ? 239 SER A CA 1 ATOM 1987 C C . SER A 1 239 ? -20.240 -13.988 -31.154 1.00 20.53 ? 239 SER A C 1 ATOM 1988 O O . SER A 1 239 ? -19.052 -13.982 -31.515 1.00 20.68 ? 239 SER A O 1 ATOM 1989 C CB . SER A 1 239 ? -21.344 -11.797 -30.563 1.00 21.17 ? 239 SER A CB 1 ATOM 1990 O OG . SER A 1 239 ? -21.744 -10.564 -31.163 1.00 22.10 ? 239 SER A OG 1 ATOM 1991 N N . VAL A 1 240 ? -20.758 -14.917 -30.350 1.00 20.41 ? 240 VAL A N 1 ATOM 1992 C CA . VAL A 1 240 ? -19.984 -16.073 -29.881 1.00 21.34 ? 240 VAL A CA 1 ATOM 1993 C C . VAL A 1 240 ? -19.520 -16.983 -31.043 1.00 22.26 ? 240 VAL A C 1 ATOM 1994 O O . VAL A 1 240 ? -18.370 -17.476 -31.048 1.00 22.63 ? 240 VAL A O 1 ATOM 1995 C CB . VAL A 1 240 ? -20.755 -16.917 -28.870 1.00 21.20 ? 240 VAL A CB 1 ATOM 1996 C CG1 . VAL A 1 240 ? -19.895 -18.119 -28.431 1.00 20.43 ? 240 VAL A CG1 1 ATOM 1997 C CG2 . VAL A 1 240 ? -21.198 -16.085 -27.661 1.00 20.97 ? 240 VAL A CG2 1 ATOM 1998 N N . LYS A 1 241 ? -20.414 -17.207 -32.010 1.00 22.35 ? 241 LYS A N 1 ATOM 1999 C CA . LYS A 1 241 ? -20.058 -17.928 -33.240 1.00 22.86 ? 241 LYS A CA 1 ATOM 2000 C C . LYS A 1 241 ? -18.959 -17.201 -33.983 1.00 22.27 ? 241 LYS A C 1 ATOM 2001 O O . LYS A 1 241 ? -18.018 -17.814 -34.456 1.00 22.17 ? 241 LYS A O 1 ATOM 2002 C CB . LYS A 1 241 ? -21.278 -18.113 -34.159 1.00 22.59 ? 241 LYS A CB 1 ATOM 2003 C CG . LYS A 1 241 ? -21.042 -19.063 -35.364 1.00 26.74 ? 241 LYS A CG 1 ATOM 2004 C CD . LYS A 1 241 ? -20.585 -20.468 -34.908 1.00 31.27 ? 241 LYS A CD 1 ATOM 2005 C CE . LYS A 1 241 ? -21.736 -21.367 -34.373 1.00 35.87 ? 241 LYS A CE 1 ATOM 2006 N NZ . LYS A 1 241 ? -22.191 -22.473 -35.319 1.00 37.05 ? 241 LYS A NZ 1 ATOM 2007 N N . THR A 1 242 ? -19.077 -15.885 -34.074 1.00 22.49 ? 242 THR A N 1 ATOM 2008 C CA . THR A 1 242 ? -18.098 -15.074 -34.773 1.00 22.97 ? 242 THR A CA 1 ATOM 2009 C C . THR A 1 242 ? -16.719 -15.109 -34.090 1.00 23.36 ? 242 THR A C 1 ATOM 2010 O O . THR A 1 242 ? -15.709 -15.264 -34.775 1.00 24.42 ? 242 THR A O 1 ATOM 2011 C CB . THR A 1 242 ? -18.635 -13.627 -34.968 1.00 22.99 ? 242 THR A CB 1 ATOM 2012 O OG1 . THR A 1 242 ? -19.858 -13.690 -35.709 1.00 22.57 ? 242 THR A OG1 1 ATOM 2013 C CG2 . THR A 1 242 ? -17.632 -12.754 -35.731 1.00 22.66 ? 242 THR A CG2 1 ATOM 2014 N N . TYR A 1 243 ? -16.670 -15.006 -32.756 1.00 23.62 ? 243 TYR A N 1 ATOM 2015 C CA . TYR A 1 243 ? -15.413 -15.155 -31.996 1.00 23.60 ? 243 TYR A CA 1 ATOM 2016 C C . TYR A 1 243 ? -14.745 -16.500 -32.276 1.00 24.36 ? 243 TYR A C 1 ATOM 2017 O O . TYR A 1 243 ? -13.530 -16.579 -32.516 1.00 24.51 ? 243 TYR A O 1 ATOM 2018 C CB . TYR A 1 243 ? -15.666 -15.062 -30.488 1.00 23.37 ? 243 TYR A CB 1 ATOM 2019 C CG . TYR A 1 243 ? -15.662 -13.662 -29.902 1.00 24.63 ? 243 TYR A CG 1 ATOM 2020 C CD1 . TYR A 1 243 ? -14.492 -12.890 -29.881 1.00 23.97 ? 243 TYR A CD1 1 ATOM 2021 C CD2 . TYR A 1 243 ? -16.818 -13.124 -29.330 1.00 24.44 ? 243 TYR A CD2 1 ATOM 2022 C CE1 . TYR A 1 243 ? -14.483 -11.616 -29.313 1.00 25.22 ? 243 TYR A CE1 1 ATOM 2023 C CE2 . TYR A 1 243 ? -16.825 -11.837 -28.778 1.00 24.65 ? 243 TYR A CE2 1 ATOM 2024 C CZ . TYR A 1 243 ? -15.655 -11.104 -28.771 1.00 25.09 ? 243 TYR A CZ 1 ATOM 2025 O OH . TYR A 1 243 ? -15.663 -9.856 -28.223 1.00 27.55 ? 243 TYR A OH 1 ATOM 2026 N N . GLN A 1 244 ? -15.549 -17.559 -32.211 1.00 24.14 ? 244 GLN A N 1 ATOM 2027 C CA . GLN A 1 244 ? -15.082 -18.902 -32.495 1.00 25.28 ? 244 GLN A CA 1 ATOM 2028 C C . GLN A 1 244 ? -14.552 -18.998 -33.938 1.00 25.05 ? 244 GLN A C 1 ATOM 2029 O O . GLN A 1 244 ? -13.460 -19.515 -34.138 1.00 24.98 ? 244 GLN A O 1 ATOM 2030 C CB . GLN A 1 244 ? -16.202 -19.923 -32.267 1.00 25.16 ? 244 GLN A CB 1 ATOM 2031 C CG . GLN A 1 244 ? -15.778 -21.372 -32.450 1.00 28.71 ? 244 GLN A CG 1 ATOM 2032 C CD . GLN A 1 244 ? -16.931 -22.336 -32.281 1.00 32.54 ? 244 GLN A CD 1 ATOM 2033 O OE1 . GLN A 1 244 ? -18.083 -22.008 -32.589 1.00 36.71 ? 244 GLN A OE1 1 ATOM 2034 N NE2 . GLN A 1 244 ? -16.635 -23.532 -31.779 1.00 33.36 ? 244 GLN A NE2 1 ATOM 2035 N N . GLU A 1 245 ? -15.319 -18.497 -34.918 1.00 24.57 ? 245 GLU A N 1 ATOM 2036 C CA . GLU A 1 245 ? -14.892 -18.535 -36.324 1.00 25.76 ? 245 GLU A CA 1 ATOM 2037 C C . GLU A 1 245 ? -13.597 -17.770 -36.594 1.00 25.08 ? 245 GLU A C 1 ATOM 2038 O O . GLU A 1 245 ? -12.734 -18.251 -37.312 1.00 25.12 ? 245 GLU A O 1 ATOM 2039 C CB . GLU A 1 245 ? -16.012 -18.091 -37.282 1.00 26.05 ? 245 GLU A CB 1 ATOM 2040 C CG . GLU A 1 245 ? -17.112 -19.156 -37.433 1.00 28.73 ? 245 GLU A CG 1 ATOM 2041 C CD . GLU A 1 245 ? -18.363 -18.674 -38.151 1.00 32.97 ? 245 GLU A CD 1 ATOM 2042 O OE1 . GLU A 1 245 ? -18.444 -17.474 -38.527 1.00 36.60 ? 245 GLU A OE1 1 ATOM 2043 O OE2 . GLU A 1 245 ? -19.288 -19.503 -38.333 1.00 35.02 ? 245 GLU A OE2 1 ATOM 2044 N N . VAL A 1 246 ? -13.456 -16.586 -36.003 1.00 25.09 ? 246 VAL A N 1 ATOM 2045 C CA . VAL A 1 246 ? -12.273 -15.756 -36.244 1.00 24.60 ? 246 VAL A CA 1 ATOM 2046 C C . VAL A 1 246 ? -11.063 -16.393 -35.552 1.00 24.72 ? 246 VAL A C 1 ATOM 2047 O O . VAL A 1 246 ? -9.960 -16.428 -36.122 1.00 24.48 ? 246 VAL A O 1 ATOM 2048 C CB . VAL A 1 246 ? -12.500 -14.276 -35.812 1.00 24.81 ? 246 VAL A CB 1 ATOM 2049 C CG1 . VAL A 1 246 ? -11.239 -13.470 -35.942 1.00 24.07 ? 246 VAL A CG1 1 ATOM 2050 C CG2 . VAL A 1 246 ? -13.590 -13.631 -36.661 1.00 25.15 ? 246 VAL A CG2 1 ATOM 2051 N N . ALA A 1 247 ? -11.277 -16.931 -34.344 1.00 24.73 ? 247 ALA A N 1 ATOM 2052 C CA . ALA A 1 247 ? -10.199 -17.616 -33.614 1.00 25.12 ? 247 ALA A CA 1 ATOM 2053 C C . ALA A 1 247 ? -9.732 -18.887 -34.352 1.00 25.32 ? 247 ALA A C 1 ATOM 2054 O O . ALA A 1 247 ? -8.532 -19.116 -34.474 1.00 23.90 ? 247 ALA A O 1 ATOM 2055 C CB . ALA A 1 247 ? -10.586 -17.915 -32.148 1.00 24.46 ? 247 ALA A CB 1 ATOM 2056 N N . GLN A 1 248 ? -10.677 -19.670 -34.876 1.00 25.86 ? 248 GLN A N 1 ATOM 2057 C CA . GLN A 1 248 ? -10.321 -20.820 -35.737 1.00 27.20 ? 248 GLN A CA 1 ATOM 2058 C C . GLN A 1 248 ? -9.479 -20.427 -36.961 1.00 26.64 ? 248 GLN A C 1 ATOM 2059 O O . GLN A 1 248 ? -8.513 -21.102 -37.286 1.00 27.05 ? 248 GLN A O 1 ATOM 2060 C CB . GLN A 1 248 ? -11.562 -21.615 -36.151 1.00 27.47 ? 248 GLN A CB 1 ATOM 2061 C CG . GLN A 1 248 ? -12.001 -22.592 -35.063 1.00 32.53 ? 248 GLN A CG 1 ATOM 2062 C CD . GLN A 1 248 ? -13.492 -22.951 -35.116 1.00 36.82 ? 248 GLN A CD 1 ATOM 2063 O OE1 . GLN A 1 248 ? -14.221 -22.560 -36.039 1.00 39.21 ? 248 GLN A OE1 1 ATOM 2064 N NE2 . GLN A 1 248 ? -13.944 -23.701 -34.114 1.00 39.25 ? 248 GLN A NE2 1 ATOM 2065 N N . LYS A 1 249 ? -9.845 -19.329 -37.612 1.00 27.13 ? 249 LYS A N 1 ATOM 2066 C CA . LYS A 1 249 ? -9.105 -18.750 -38.732 1.00 27.48 ? 249 LYS A CA 1 ATOM 2067 C C . LYS A 1 249 ? -7.654 -18.341 -38.358 1.00 27.85 ? 249 LYS A C 1 ATOM 2068 O O . LYS A 1 249 ? -6.689 -18.654 -39.073 1.00 27.20 ? 249 LYS A O 1 ATOM 2069 C CB . LYS A 1 249 ? -9.895 -17.539 -39.241 1.00 28.05 ? 249 LYS A CB 1 ATOM 2070 C CG . LYS A 1 249 ? -9.325 -16.797 -40.440 1.00 30.71 ? 249 LYS A CG 1 ATOM 2071 C CD . LYS A 1 249 ? -9.810 -17.407 -41.757 1.00 36.86 ? 249 LYS A CD 1 ATOM 2072 C CE . LYS A 1 249 ? -9.553 -16.454 -42.925 1.00 39.63 ? 249 LYS A CE 1 ATOM 2073 N NZ . LYS A 1 249 ? -10.077 -16.951 -44.236 1.00 42.25 ? 249 LYS A NZ 1 ATOM 2074 N N . PHE A 1 250 ? -7.514 -17.638 -37.238 1.00 26.91 ? 250 PHE A N 1 ATOM 2075 C CA . PHE A 1 250 ? -6.208 -17.274 -36.714 1.00 26.33 ? 250 PHE A CA 1 ATOM 2076 C C . PHE A 1 250 ? -5.321 -18.504 -36.413 1.00 27.15 ? 250 PHE A C 1 ATOM 2077 O O . PHE A 1 250 ? -4.135 -18.511 -36.745 1.00 26.45 ? 250 PHE A O 1 ATOM 2078 C CB . PHE A 1 250 ? -6.365 -16.373 -35.468 1.00 26.01 ? 250 PHE A CB 1 ATOM 2079 C CG . PHE A 1 250 ? -5.081 -15.735 -35.034 1.00 23.13 ? 250 PHE A CG 1 ATOM 2080 C CD1 . PHE A 1 250 ? -4.663 -14.543 -35.608 1.00 20.66 ? 250 PHE A CD1 1 ATOM 2081 C CD2 . PHE A 1 250 ? -4.273 -16.352 -34.080 1.00 21.31 ? 250 PHE A CD2 1 ATOM 2082 C CE1 . PHE A 1 250 ? -3.436 -13.958 -35.258 1.00 21.23 ? 250 PHE A CE1 1 ATOM 2083 C CE2 . PHE A 1 250 ? -3.055 -15.782 -33.695 1.00 20.27 ? 250 PHE A CE2 1 ATOM 2084 C CZ . PHE A 1 250 ? -2.626 -14.571 -34.296 1.00 19.75 ? 250 PHE A CZ 1 ATOM 2085 N N . VAL A 1 251 ? -5.894 -19.536 -35.797 1.00 28.13 ? 251 VAL A N 1 ATOM 2086 C CA . VAL A 1 251 ? -5.138 -20.743 -35.451 1.00 29.94 ? 251 VAL A CA 1 ATOM 2087 C C . VAL A 1 251 ? -4.611 -21.468 -36.706 1.00 31.35 ? 251 VAL A C 1 ATOM 2088 O O . VAL A 1 251 ? -3.492 -22.026 -36.693 1.00 31.62 ? 251 VAL A O 1 ATOM 2089 C CB . VAL A 1 251 ? -5.943 -21.676 -34.501 1.00 29.73 ? 251 VAL A CB 1 ATOM 2090 C CG1 . VAL A 1 251 ? -5.276 -23.030 -34.344 1.00 29.93 ? 251 VAL A CG1 1 ATOM 2091 C CG2 . VAL A 1 251 ? -6.140 -21.015 -33.121 1.00 29.69 ? 251 VAL A CG2 1 ATOM 2092 N N . GLU A 1 252 ? -5.388 -21.418 -37.790 1.00 33.07 ? 252 GLU A N 1 ATOM 2093 C CA . GLU A 1 252 ? -4.972 -21.988 -39.087 1.00 34.62 ? 252 GLU A CA 1 ATOM 2094 C C . GLU A 1 252 ? -3.603 -21.524 -39.544 1.00 34.75 ? 252 GLU A C 1 ATOM 2095 O O . GLU A 1 252 ? -2.801 -22.330 -40.002 1.00 35.26 ? 252 GLU A O 1 ATOM 2096 C CB . GLU A 1 252 ? -6.003 -21.724 -40.188 1.00 34.75 ? 252 GLU A CB 1 ATOM 2097 C CG . GLU A 1 252 ? -7.204 -22.641 -40.085 1.00 37.64 ? 252 GLU A CG 1 ATOM 2098 C CD . GLU A 1 252 ? -8.273 -22.400 -41.156 1.00 41.66 ? 252 GLU A CD 1 ATOM 2099 O OE1 . GLU A 1 252 ? -8.086 -21.550 -42.068 1.00 42.19 ? 252 GLU A OE1 1 ATOM 2100 O OE2 . GLU A 1 252 ? -9.320 -23.087 -41.078 1.00 44.83 ? 252 GLU A OE2 1 ATOM 2101 N N . THR A 1 253 ? -3.329 -20.235 -39.399 1.00 34.89 ? 253 THR A N 1 ATOM 2102 C CA . THR A 1 253 ? -2.023 -19.690 -39.770 1.00 35.21 ? 253 THR A CA 1 ATOM 2103 C C . THR A 1 253 ? -1.061 -19.479 -38.597 1.00 34.33 ? 253 THR A C 1 ATOM 2104 O O . THR A 1 253 ? 0.096 -19.110 -38.796 1.00 34.85 ? 253 THR A O 1 ATOM 2105 C CB . THR A 1 253 ? -2.171 -18.386 -40.560 1.00 35.48 ? 253 THR A CB 1 ATOM 2106 O OG1 . THR A 1 253 ? -3.056 -17.505 -39.856 1.00 38.25 ? 253 THR A OG1 1 ATOM 2107 C CG2 . THR A 1 253 ? -2.740 -18.689 -41.965 1.00 36.30 ? 253 THR A CG2 1 ATOM 2108 N N . HIS A 1 254 ? -1.540 -19.717 -37.384 1.00 33.12 ? 254 HIS A N 1 ATOM 2109 C CA . HIS A 1 254 ? -0.725 -19.596 -36.184 1.00 32.22 ? 254 HIS A CA 1 ATOM 2110 C C . HIS A 1 254 ? -0.904 -20.849 -35.312 1.00 32.00 ? 254 HIS A C 1 ATOM 2111 O O . HIS A 1 254 ? -1.579 -20.788 -34.281 1.00 31.93 ? 254 HIS A O 1 ATOM 2112 C CB . HIS A 1 254 ? -1.113 -18.336 -35.400 1.00 32.05 ? 254 HIS A CB 1 ATOM 2113 C CG . HIS A 1 254 ? -0.956 -17.063 -36.178 1.00 30.34 ? 254 HIS A CG 1 ATOM 2114 N ND1 . HIS A 1 254 ? -1.928 -16.587 -37.033 1.00 30.39 ? 254 HIS A ND1 1 ATOM 2115 C CD2 . HIS A 1 254 ? 0.052 -16.161 -36.220 1.00 28.63 ? 254 HIS A CD2 1 ATOM 2116 C CE1 . HIS A 1 254 ? -1.525 -15.452 -37.575 1.00 28.68 ? 254 HIS A CE1 1 ATOM 2117 N NE2 . HIS A 1 254 ? -0.326 -15.172 -37.099 1.00 28.74 ? 254 HIS A NE2 1 ATOM 2118 N N . PRO A 1 255 ? -0.291 -21.985 -35.718 1.00 31.31 ? 255 PRO A N 1 ATOM 2119 C CA . PRO A 1 255 ? -0.595 -23.292 -35.124 1.00 30.86 ? 255 PRO A CA 1 ATOM 2120 C C . PRO A 1 255 ? -0.229 -23.452 -33.640 1.00 30.26 ? 255 PRO A C 1 ATOM 2121 O O . PRO A 1 255 ? -0.779 -24.324 -32.974 1.00 29.85 ? 255 PRO A O 1 ATOM 2122 C CB . PRO A 1 255 ? 0.206 -24.282 -36.000 1.00 30.90 ? 255 PRO A CB 1 ATOM 2123 C CG . PRO A 1 255 ? 0.505 -23.550 -37.235 1.00 31.04 ? 255 PRO A CG 1 ATOM 2124 C CD . PRO A 1 255 ? 0.650 -22.115 -36.847 1.00 31.49 ? 255 PRO A CD 1 ATOM 2125 N N . GLU A 1 256 ? 0.671 -22.619 -33.118 1.00 30.16 ? 256 GLU A N 1 ATOM 2126 C CA . GLU A 1 256 ? 0.972 -22.655 -31.678 1.00 29.30 ? 256 GLU A CA 1 ATOM 2127 C C . GLU A 1 256 ? -0.009 -21.817 -30.837 1.00 28.54 ? 256 GLU A C 1 ATOM 2128 O O . GLU A 1 256 ? -0.021 -21.931 -29.622 1.00 28.36 ? 256 GLU A O 1 ATOM 2129 C CB . GLU A 1 256 ? 2.418 -22.225 -31.385 1.00 29.82 ? 256 GLU A CB 1 ATOM 2130 C CG . GLU A 1 256 ? 3.488 -23.077 -32.028 1.00 29.57 ? 256 GLU A CG 1 ATOM 2131 C CD . GLU A 1 256 ? 4.862 -22.449 -31.877 1.00 31.28 ? 256 GLU A CD 1 ATOM 2132 O OE1 . GLU A 1 256 ? 5.377 -21.910 -32.880 1.00 34.26 ? 256 GLU A OE1 1 ATOM 2133 O OE2 . GLU A 1 256 ? 5.412 -22.455 -30.750 1.00 31.69 ? 256 GLU A OE2 1 ATOM 2134 N N . PHE A 1 257 ? -0.821 -20.982 -31.479 1.00 27.93 ? 257 PHE A N 1 ATOM 2135 C CA . PHE A 1 257 ? -1.845 -20.233 -30.773 1.00 27.44 ? 257 PHE A CA 1 ATOM 2136 C C . PHE A 1 257 ? -2.958 -21.218 -30.374 1.00 27.35 ? 257 PHE A C 1 ATOM 2137 O O . PHE A 1 257 ? -3.420 -22.011 -31.190 1.00 27.84 ? 257 PHE A O 1 ATOM 2138 C CB . PHE A 1 257 ? -2.381 -19.065 -31.623 1.00 26.56 ? 257 PHE A CB 1 ATOM 2139 C CG . PHE A 1 257 ? -3.127 -18.017 -30.823 1.00 26.39 ? 257 PHE A CG 1 ATOM 2140 C CD1 . PHE A 1 257 ? -2.428 -17.012 -30.124 1.00 27.59 ? 257 PHE A CD1 1 ATOM 2141 C CD2 . PHE A 1 257 ? -4.523 -18.022 -30.763 1.00 24.57 ? 257 PHE A CD2 1 ATOM 2142 C CE1 . PHE A 1 257 ? -3.115 -16.033 -29.387 1.00 24.09 ? 257 PHE A CE1 1 ATOM 2143 C CE2 . PHE A 1 257 ? -5.206 -17.058 -30.026 1.00 25.63 ? 257 PHE A CE2 1 ATOM 2144 C CZ . PHE A 1 257 ? -4.504 -16.059 -29.346 1.00 25.04 ? 257 PHE A CZ 1 ATOM 2145 N N . ILE A 1 258 ? -3.338 -21.198 -29.101 1.00 26.93 ? 258 ILE A N 1 ATOM 2146 C CA . ILE A 1 258 ? -4.317 -22.143 -28.565 1.00 26.49 ? 258 ILE A CA 1 ATOM 2147 C C . ILE A 1 258 ? -5.746 -21.711 -28.943 1.00 26.45 ? 258 ILE A C 1 ATOM 2148 O O . ILE A 1 258 ? -6.567 -22.557 -29.252 1.00 26.76 ? 258 ILE A O 1 ATOM 2149 C CB . ILE A 1 258 ? -4.177 -22.319 -27.014 1.00 26.41 ? 258 ILE A CB 1 ATOM 2150 C CG1 . ILE A 1 258 ? -2.722 -22.640 -26.606 1.00 27.18 ? 258 ILE A CG1 1 ATOM 2151 C CG2 . ILE A 1 258 ? -5.188 -23.352 -26.445 1.00 25.48 ? 258 ILE A CG2 1 ATOM 2152 C CD1 . ILE A 1 258 ? -2.172 -24.004 -27.087 1.00 25.79 ? 258 ILE A CD1 1 ATOM 2153 N N . GLY A 1 259 ? -6.024 -20.405 -28.918 1.00 26.05 ? 259 GLY A N 1 ATOM 2154 C CA . GLY A 1 259 ? -7.353 -19.874 -29.245 1.00 25.35 ? 259 GLY A CA 1 ATOM 2155 C C . GLY A 1 259 ? -7.885 -18.951 -28.157 1.00 25.47 ? 259 GLY A C 1 ATOM 2156 O O . GLY A 1 259 ? -7.115 -18.440 -27.335 1.00 24.35 ? 259 GLY A O 1 ATOM 2157 N N . ILE A 1 260 ? -9.202 -18.714 -28.157 1.00 24.58 ? 260 ILE A N 1 ATOM 2158 C CA . ILE A 1 260 ? -9.804 -17.835 -27.149 1.00 24.47 ? 260 ILE A CA 1 ATOM 2159 C C . ILE A 1 260 ? -11.035 -18.455 -26.533 1.00 24.01 ? 260 ILE A C 1 ATOM 2160 O O . ILE A 1 260 ? -11.718 -19.240 -27.187 1.00 23.86 ? 260 ILE A O 1 ATOM 2161 C CB . ILE A 1 260 ? -10.171 -16.417 -27.701 1.00 24.67 ? 260 ILE A CB 1 ATOM 2162 C CG1 . ILE A 1 260 ? -11.294 -16.473 -28.733 1.00 26.67 ? 260 ILE A CG1 1 ATOM 2163 C CG2 . ILE A 1 260 ? -8.923 -15.707 -28.265 1.00 26.66 ? 260 ILE A CG2 1 ATOM 2164 C CD1 . ILE A 1 260 ? -11.577 -15.108 -29.443 1.00 30.40 ? 260 ILE A CD1 1 ATOM 2165 N N . LYS A 1 261 ? -11.318 -18.104 -25.276 1.00 22.40 ? 261 LYS A N 1 ATOM 2166 C CA . LYS A 1 261 ? -12.640 -18.374 -24.711 1.00 21.51 ? 261 LYS A CA 1 ATOM 2167 C C . LYS A 1 261 ? -13.297 -17.093 -24.233 1.00 21.30 ? 261 LYS A C 1 ATOM 2168 O O . LYS A 1 261 ? -12.614 -16.072 -23.991 1.00 21.54 ? 261 LYS A O 1 ATOM 2169 C CB . LYS A 1 261 ? -12.572 -19.411 -23.584 1.00 21.30 ? 261 LYS A CB 1 ATOM 2170 C CG . LYS A 1 261 ? -12.175 -20.766 -24.085 1.00 21.75 ? 261 LYS A CG 1 ATOM 2171 C CD . LYS A 1 261 ? -12.672 -21.827 -23.136 1.00 25.34 ? 261 LYS A CD 1 ATOM 2172 C CE . LYS A 1 261 ? -11.911 -23.115 -23.316 1.00 30.68 ? 261 LYS A CE 1 ATOM 2173 N NZ . LYS A 1 261 ? -11.908 -23.592 -24.740 1.00 33.88 ? 261 LYS A NZ 1 ATOM 2174 N N . ILE A 1 262 ? -14.618 -17.153 -24.097 1.00 20.85 ? 262 ILE A N 1 ATOM 2175 C CA . ILE A 1 262 ? -15.431 -15.997 -23.755 1.00 21.15 ? 262 ILE A CA 1 ATOM 2176 C C . ILE A 1 262 ? -16.042 -16.191 -22.366 1.00 20.94 ? 262 ILE A C 1 ATOM 2177 O O . ILE A 1 262 ? -16.591 -17.271 -22.050 1.00 21.11 ? 262 ILE A O 1 ATOM 2178 C CB . ILE A 1 262 ? -16.573 -15.763 -24.840 1.00 21.11 ? 262 ILE A CB 1 ATOM 2179 C CG1 . ILE A 1 262 ? -15.976 -15.463 -26.216 1.00 22.66 ? 262 ILE A CG1 1 ATOM 2180 C CG2 . ILE A 1 262 ? -17.520 -14.648 -24.441 1.00 22.17 ? 262 ILE A CG2 1 ATOM 2181 C CD1 . ILE A 1 262 ? -14.906 -14.312 -26.233 1.00 23.69 ? 262 ILE A CD1 1 ATOM 2182 N N . ILE A 1 263 ? -15.927 -15.154 -21.538 1.00 19.90 ? 263 ILE A N 1 ATOM 2183 C CA . ILE A 1 263 ? -16.653 -15.075 -20.279 1.00 19.11 ? 263 ILE A CA 1 ATOM 2184 C C . ILE A 1 263 ? -17.693 -14.013 -20.518 1.00 18.74 ? 263 ILE A C 1 ATOM 2185 O O . ILE A 1 263 ? -17.358 -12.866 -20.693 1.00 19.00 ? 263 ILE A O 1 ATOM 2186 C CB . ILE A 1 263 ? -15.746 -14.676 -19.086 1.00 19.01 ? 263 ILE A CB 1 ATOM 2187 C CG1 . ILE A 1 263 ? -14.661 -15.754 -18.878 1.00 19.02 ? 263 ILE A CG1 1 ATOM 2188 C CG2 . ILE A 1 263 ? -16.602 -14.458 -17.783 1.00 18.09 ? 263 ILE A CG2 1 ATOM 2189 C CD1 . ILE A 1 263 ? -13.491 -15.271 -18.022 1.00 17.95 ? 263 ILE A CD1 1 ATOM 2190 N N . TYR A 1 264 ? -18.955 -14.418 -20.576 1.00 19.10 ? 264 TYR A N 1 ATOM 2191 C CA . TYR A 1 264 ? -20.029 -13.470 -20.808 1.00 19.09 ? 264 TYR A CA 1 ATOM 2192 C C . TYR A 1 264 ? -20.193 -12.566 -19.587 1.00 18.21 ? 264 TYR A C 1 ATOM 2193 O O . TYR A 1 264 ? -20.215 -13.034 -18.466 1.00 16.99 ? 264 TYR A O 1 ATOM 2194 C CB . TYR A 1 264 ? -21.323 -14.223 -21.124 1.00 19.90 ? 264 TYR A CB 1 ATOM 2195 C CG . TYR A 1 264 ? -22.568 -13.370 -21.255 1.00 21.60 ? 264 TYR A CG 1 ATOM 2196 C CD1 . TYR A 1 264 ? -22.582 -12.214 -22.030 1.00 24.78 ? 264 TYR A CD1 1 ATOM 2197 C CD2 . TYR A 1 264 ? -23.758 -13.757 -20.649 1.00 23.96 ? 264 TYR A CD2 1 ATOM 2198 C CE1 . TYR A 1 264 ? -23.757 -11.448 -22.171 1.00 24.90 ? 264 TYR A CE1 1 ATOM 2199 C CE2 . TYR A 1 264 ? -24.924 -13.003 -20.793 1.00 24.94 ? 264 TYR A CE2 1 ATOM 2200 C CZ . TYR A 1 264 ? -24.911 -11.861 -21.549 1.00 26.25 ? 264 TYR A CZ 1 ATOM 2201 O OH . TYR A 1 264 ? -26.067 -11.118 -21.687 1.00 30.04 ? 264 TYR A OH 1 ATOM 2202 N N . SER A 1 265 ? -20.272 -11.262 -19.819 1.00 18.13 ? 265 SER A N 1 ATOM 2203 C CA . SER A 1 265 ? -20.364 -10.293 -18.704 1.00 18.82 ? 265 SER A CA 1 ATOM 2204 C C . SER A 1 265 ? -21.522 -9.312 -18.886 1.00 18.72 ? 265 SER A C 1 ATOM 2205 O O . SER A 1 265 ? -21.952 -9.093 -20.000 1.00 19.19 ? 265 SER A O 1 ATOM 2206 C CB . SER A 1 265 ? -19.061 -9.527 -18.570 1.00 18.75 ? 265 SER A CB 1 ATOM 2207 O OG . SER A 1 265 ? -18.858 -8.735 -19.737 1.00 21.30 ? 265 SER A OG 1 ATOM 2208 N N . ASP A 1 266 ? -22.038 -8.780 -17.783 1.00 18.07 ? 266 ASP A N 1 ATOM 2209 C CA . ASP A 1 266 ? -23.041 -7.723 -17.823 1.00 19.93 ? 266 ASP A CA 1 ATOM 2210 C C . ASP A 1 266 ? -22.727 -6.683 -16.737 1.00 19.70 ? 266 ASP A C 1 ATOM 2211 O O . ASP A 1 266 ? -22.009 -6.972 -15.779 1.00 20.16 ? 266 ASP A O 1 ATOM 2212 C CB . ASP A 1 266 ? -24.470 -8.278 -17.659 1.00 18.86 ? 266 ASP A CB 1 ATOM 2213 C CG . ASP A 1 266 ? -25.530 -7.350 -18.251 1.00 22.90 ? 266 ASP A CG 1 ATOM 2214 O OD1 . ASP A 1 266 ? -25.185 -6.220 -18.709 1.00 22.87 ? 266 ASP A OD1 1 ATOM 2215 O OD2 . ASP A 1 266 ? -26.719 -7.743 -18.260 1.00 26.39 ? 266 ASP A OD2 1 ATOM 2216 N N . HIS A 1 267 ? -23.248 -5.476 -16.912 1.00 20.66 ? 267 HIS A N 1 ATOM 2217 C CA . HIS A 1 267 ? -22.883 -4.329 -16.083 1.00 21.30 ? 267 HIS A CA 1 ATOM 2218 C C . HIS A 1 267 ? -23.540 -4.355 -14.693 1.00 22.03 ? 267 HIS A C 1 ATOM 2219 O O . HIS A 1 267 ? -24.753 -4.567 -14.565 1.00 21.78 ? 267 HIS A O 1 ATOM 2220 C CB . HIS A 1 267 ? -23.207 -3.029 -16.832 1.00 21.13 ? 267 HIS A CB 1 ATOM 2221 C CG . HIS A 1 267 ? -22.437 -1.846 -16.337 1.00 21.65 ? 267 HIS A CG 1 ATOM 2222 N ND1 . HIS A 1 267 ? -22.906 -1.013 -15.339 1.00 24.11 ? 267 HIS A ND1 1 ATOM 2223 C CD2 . HIS A 1 267 ? -21.220 -1.363 -16.688 1.00 21.75 ? 267 HIS A CD2 1 ATOM 2224 C CE1 . HIS A 1 267 ? -22.010 -0.071 -15.096 1.00 23.35 ? 267 HIS A CE1 1 ATOM 2225 N NE2 . HIS A 1 267 ? -20.981 -0.258 -15.904 1.00 23.89 ? 267 HIS A NE2 1 ATOM 2226 N N . ARG A 1 268 ? -22.743 -4.107 -13.653 1.00 21.95 ? 268 ARG A N 1 ATOM 2227 C CA . ARG A 1 268 ? -23.244 -4.192 -12.272 1.00 22.49 ? 268 ARG A CA 1 ATOM 2228 C C . ARG A 1 268 ? -24.057 -2.948 -11.833 1.00 22.35 ? 268 ARG A C 1 ATOM 2229 O O . ARG A 1 268 ? -24.384 -2.817 -10.655 1.00 22.84 ? 268 ARG A O 1 ATOM 2230 C CB . ARG A 1 268 ? -22.097 -4.512 -11.265 1.00 21.49 ? 268 ARG A CB 1 ATOM 2231 C CG . ARG A 1 268 ? -21.057 -3.401 -11.117 1.00 20.41 ? 268 ARG A CG 1 ATOM 2232 C CD . ARG A 1 268 ? -19.774 -3.833 -10.350 1.00 19.35 ? 268 ARG A CD 1 ATOM 2233 N NE . ARG A 1 268 ? -20.067 -4.588 -9.132 1.00 18.62 ? 268 ARG A NE 1 ATOM 2234 C CZ . ARG A 1 268 ? -19.572 -5.792 -8.870 1.00 22.58 ? 268 ARG A CZ 1 ATOM 2235 N NH1 . ARG A 1 268 ? -18.743 -6.365 -9.743 1.00 23.56 ? 268 ARG A NH1 1 ATOM 2236 N NH2 . ARG A 1 268 ? -19.908 -6.428 -7.749 1.00 21.49 ? 268 ARG A NH2 1 ATOM 2237 N N . SER A 1 269 ? -24.381 -2.040 -12.747 1.00 23.70 ? 269 SER A N 1 ATOM 2238 C CA . SER A 1 269 ? -25.337 -0.944 -12.415 1.00 23.99 ? 269 SER A CA 1 ATOM 2239 C C . SER A 1 269 ? -26.797 -1.401 -12.595 1.00 24.80 ? 269 SER A C 1 ATOM 2240 O O . SER A 1 269 ? -27.724 -0.725 -12.124 1.00 25.13 ? 269 SER A O 1 ATOM 2241 C CB . SER A 1 269 ? -25.095 0.300 -13.267 1.00 24.53 ? 269 SER A CB 1 ATOM 2242 O OG . SER A 1 269 ? -25.317 0.018 -14.646 1.00 25.84 ? 269 SER A OG 1 ATOM 2243 N N . LYS A 1 270 ? -26.989 -2.563 -13.234 1.00 24.70 ? 270 LYS A N 1 ATOM 2244 C CA . LYS A 1 270 ? -28.298 -3.051 -13.666 1.00 24.76 ? 270 LYS A CA 1 ATOM 2245 C C . LYS A 1 270 ? -29.150 -3.697 -12.551 1.00 25.71 ? 270 LYS A C 1 ATOM 2246 O O . LYS A 1 270 ? -28.618 -4.209 -11.562 1.00 24.16 ? 270 LYS A O 1 ATOM 2247 C CB . LYS A 1 270 ? -28.117 -4.041 -14.827 1.00 24.84 ? 270 LYS A CB 1 ATOM 2248 C CG . LYS A 1 270 ? -27.574 -3.470 -16.139 1.00 25.03 ? 270 LYS A CG 1 ATOM 2249 C CD . LYS A 1 270 ? -27.945 -4.417 -17.270 1.00 26.68 ? 270 LYS A CD 1 ATOM 2250 C CE . LYS A 1 270 ? -27.163 -4.237 -18.564 1.00 28.78 ? 270 LYS A CE 1 ATOM 2251 N NZ . LYS A 1 270 ? -27.222 -2.855 -19.030 1.00 29.57 ? 270 LYS A NZ 1 ATOM 2252 N N . ASP A 1 271 ? -30.483 -3.699 -12.721 1.00 26.86 ? 271 ASP A N 1 ATOM 2253 C CA . ASP A 1 271 ? -31.381 -4.270 -11.693 1.00 28.22 ? 271 ASP A CA 1 ATOM 2254 C C . ASP A 1 271 ? -31.253 -5.780 -11.641 1.00 28.57 ? 271 ASP A C 1 ATOM 2255 O O . ASP A 1 271 ? -30.915 -6.401 -12.663 1.00 28.81 ? 271 ASP A O 1 ATOM 2256 C CB . ASP A 1 271 ? -32.850 -3.878 -11.959 1.00 29.78 ? 271 ASP A CB 1 ATOM 2257 C CG . ASP A 1 271 ? -33.094 -2.390 -11.798 1.00 32.87 ? 271 ASP A CG 1 ATOM 2258 O OD1 . ASP A 1 271 ? -32.661 -1.826 -10.772 1.00 38.27 ? 271 ASP A OD1 1 ATOM 2259 O OD2 . ASP A 1 271 ? -33.726 -1.778 -12.690 1.00 37.57 ? 271 ASP A OD2 1 ATOM 2260 N N . VAL A 1 272 ? -31.540 -6.379 -10.478 1.00 28.69 ? 272 VAL A N 1 ATOM 2261 C CA . VAL A 1 272 ? -31.355 -7.826 -10.295 1.00 29.34 ? 272 VAL A CA 1 ATOM 2262 C C . VAL A 1 272 ? -32.183 -8.679 -11.263 1.00 29.91 ? 272 VAL A C 1 ATOM 2263 O O . VAL A 1 272 ? -31.736 -9.757 -11.676 1.00 29.74 ? 272 VAL A O 1 ATOM 2264 C CB . VAL A 1 272 ? -31.504 -8.296 -8.796 1.00 29.71 ? 272 VAL A CB 1 ATOM 2265 C CG1 . VAL A 1 272 ? -32.709 -7.679 -8.103 1.00 30.24 ? 272 VAL A CG1 1 ATOM 2266 C CG2 . VAL A 1 272 ? -31.557 -9.800 -8.690 1.00 30.19 ? 272 VAL A CG2 1 ATOM 2267 N N . ALA A 1 273 ? -33.378 -8.203 -11.623 1.00 29.33 ? 273 ALA A N 1 ATOM 2268 C CA . ALA A 1 273 ? -34.207 -8.909 -12.603 1.00 29.32 ? 273 ALA A CA 1 ATOM 2269 C C . ALA A 1 273 ? -33.556 -8.947 -13.985 1.00 28.56 ? 273 ALA A C 1 ATOM 2270 O O . ALA A 1 273 ? -33.688 -9.933 -14.711 1.00 28.85 ? 273 ALA A O 1 ATOM 2271 C CB . ALA A 1 273 ? -35.606 -8.276 -12.700 1.00 29.87 ? 273 ALA A CB 1 ATOM 2272 N N . VAL A 1 274 ? -32.850 -7.881 -14.341 1.00 27.68 ? 274 VAL A N 1 ATOM 2273 C CA . VAL A 1 274 ? -32.195 -7.799 -15.628 1.00 26.71 ? 274 VAL A CA 1 ATOM 2274 C C . VAL A 1 274 ? -30.990 -8.731 -15.643 1.00 26.30 ? 274 VAL A C 1 ATOM 2275 O O . VAL A 1 274 ? -30.740 -9.416 -16.633 1.00 26.21 ? 274 VAL A O 1 ATOM 2276 C CB . VAL A 1 274 ? -31.799 -6.344 -15.955 1.00 26.85 ? 274 VAL A CB 1 ATOM 2277 C CG1 . VAL A 1 274 ? -30.921 -6.267 -17.193 1.00 25.02 ? 274 VAL A CG1 1 ATOM 2278 C CG2 . VAL A 1 274 ? -33.062 -5.474 -16.128 1.00 27.70 ? 274 VAL A CG2 1 ATOM 2279 N N . ILE A 1 275 ? -30.264 -8.759 -14.526 1.00 25.47 ? 275 ILE A N 1 ATOM 2280 C CA . ILE A 1 275 ? -29.125 -9.645 -14.354 1.00 24.69 ? 275 ILE A CA 1 ATOM 2281 C C . ILE A 1 275 ? -29.571 -11.113 -14.356 1.00 24.86 ? 275 ILE A C 1 ATOM 2282 O O . ILE A 1 275 ? -28.898 -11.955 -14.944 1.00 24.53 ? 275 ILE A O 1 ATOM 2283 C CB . ILE A 1 275 ? -28.288 -9.264 -13.084 1.00 24.18 ? 275 ILE A CB 1 ATOM 2284 C CG1 . ILE A 1 275 ? -27.680 -7.845 -13.230 1.00 22.71 ? 275 ILE A CG1 1 ATOM 2285 C CG2 . ILE A 1 275 ? -27.236 -10.328 -12.770 1.00 23.43 ? 275 ILE A CG2 1 ATOM 2286 C CD1 . ILE A 1 275 ? -26.837 -7.562 -14.533 1.00 18.58 ? 275 ILE A CD1 1 ATOM 2287 N N . ALA A 1 276 ? -30.716 -11.416 -13.730 1.00 25.67 ? 276 ALA A N 1 ATOM 2288 C CA . ALA A 1 276 ? -31.268 -12.788 -13.766 1.00 25.33 ? 276 ALA A CA 1 ATOM 2289 C C . ALA A 1 276 ? -31.452 -13.257 -15.227 1.00 25.35 ? 276 ALA A C 1 ATOM 2290 O O . ALA A 1 276 ? -31.194 -14.408 -15.561 1.00 25.13 ? 276 ALA A O 1 ATOM 2291 C CB . ALA A 1 276 ? -32.596 -12.865 -12.999 1.00 25.75 ? 276 ALA A CB 1 ATOM 2292 N N . GLU A 1 277 ? -31.882 -12.341 -16.095 1.00 25.60 ? 277 GLU A N 1 ATOM 2293 C CA . GLU A 1 277 ? -32.003 -12.631 -17.525 1.00 25.74 ? 277 GLU A CA 1 ATOM 2294 C C . GLU A 1 277 ? -30.657 -12.882 -18.220 1.00 24.96 ? 277 GLU A C 1 ATOM 2295 O O . GLU A 1 277 ? -30.563 -13.713 -19.128 1.00 23.72 ? 277 GLU A O 1 ATOM 2296 C CB . GLU A 1 277 ? -32.729 -11.479 -18.219 1.00 26.23 ? 277 GLU A CB 1 ATOM 2297 C CG . GLU A 1 277 ? -33.011 -11.747 -19.680 1.00 29.78 ? 277 GLU A CG 1 ATOM 2298 C CD . GLU A 1 277 ? -33.831 -10.641 -20.322 1.00 34.72 ? 277 GLU A CD 1 ATOM 2299 O OE1 . GLU A 1 277 ? -33.289 -9.523 -20.506 1.00 37.70 ? 277 GLU A OE1 1 ATOM 2300 O OE2 . GLU A 1 277 ? -35.006 -10.897 -20.651 1.00 37.52 ? 277 GLU A OE2 1 ATOM 2301 N N . SER A 1 278 ? -29.628 -12.143 -17.812 1.00 24.31 ? 278 SER A N 1 ATOM 2302 C CA . SER A 1 278 ? -28.274 -12.372 -18.315 1.00 24.12 ? 278 SER A CA 1 ATOM 2303 C C . SER A 1 278 ? -27.757 -13.734 -17.893 1.00 23.63 ? 278 SER A C 1 ATOM 2304 O O . SER A 1 278 ? -27.066 -14.383 -18.664 1.00 24.01 ? 278 SER A O 1 ATOM 2305 C CB . SER A 1 278 ? -27.311 -11.272 -17.847 1.00 24.00 ? 278 SER A CB 1 ATOM 2306 O OG . SER A 1 278 ? -27.771 -10.016 -18.320 1.00 25.39 ? 278 SER A OG 1 ATOM 2307 N N . ILE A 1 279 ? -28.087 -14.140 -16.671 1.00 23.33 ? 279 ILE A N 1 ATOM 2308 C CA . ILE A 1 279 ? -27.700 -15.440 -16.124 1.00 23.49 ? 279 ILE A CA 1 ATOM 2309 C C . ILE A 1 279 ? -28.317 -16.577 -16.952 1.00 23.88 ? 279 ILE A C 1 ATOM 2310 O O . ILE A 1 279 ? -27.622 -17.516 -17.309 1.00 23.89 ? 279 ILE A O 1 ATOM 2311 C CB . ILE A 1 279 ? -28.076 -15.573 -14.625 1.00 23.35 ? 279 ILE A CB 1 ATOM 2312 C CG1 . ILE A 1 279 ? -27.230 -14.628 -13.759 1.00 25.61 ? 279 ILE A CG1 1 ATOM 2313 C CG2 . ILE A 1 279 ? -27.930 -17.033 -14.122 1.00 22.49 ? 279 ILE A CG2 1 ATOM 2314 C CD1 . ILE A 1 279 ? -25.769 -15.009 -13.650 1.00 25.25 ? 279 ILE A CD1 1 ATOM 2315 N N . ARG A 1 280 ? -29.616 -16.484 -17.259 1.00 23.91 ? 280 ARG A N 1 ATOM 2316 C CA . ARG A 1 280 ? -30.261 -17.478 -18.133 1.00 24.40 ? 280 ARG A CA 1 ATOM 2317 C C . ARG A 1 280 ? -29.627 -17.540 -19.511 1.00 23.95 ? 280 ARG A C 1 ATOM 2318 O O . ARG A 1 280 ? -29.374 -18.636 -20.032 1.00 23.67 ? 280 ARG A O 1 ATOM 2319 C CB . ARG A 1 280 ? -31.776 -17.230 -18.235 1.00 23.56 ? 280 ARG A CB 1 ATOM 2320 C CG . ARG A 1 280 ? -32.463 -17.525 -16.944 1.00 26.91 ? 280 ARG A CG 1 ATOM 2321 C CD . ARG A 1 280 ? -33.980 -17.264 -16.926 1.00 31.69 ? 280 ARG A CD 1 ATOM 2322 N NE . ARG A 1 280 ? -34.551 -18.149 -15.910 1.00 36.18 ? 280 ARG A NE 1 ATOM 2323 C CZ . ARG A 1 280 ? -34.638 -17.855 -14.618 1.00 38.72 ? 280 ARG A CZ 1 ATOM 2324 N NH1 . ARG A 1 280 ? -34.220 -16.674 -14.185 1.00 42.66 ? 280 ARG A NH1 1 ATOM 2325 N NH2 . ARG A 1 280 ? -35.148 -18.730 -13.756 1.00 39.16 ? 280 ARG A NH2 1 ATOM 2326 N N . MET A 1 281 ? -29.396 -16.365 -20.100 1.00 24.19 ? 281 MET A N 1 ATOM 2327 C CA . MET A 1 281 ? -28.610 -16.233 -21.336 1.00 25.24 ? 281 MET A CA 1 ATOM 2328 C C . MET A 1 281 ? -27.239 -16.935 -21.218 1.00 25.12 ? 281 MET A C 1 ATOM 2329 O O . MET A 1 281 ? -26.868 -17.719 -22.096 1.00 24.41 ? 281 MET A O 1 ATOM 2330 C CB . MET A 1 281 ? -28.449 -14.743 -21.694 1.00 25.75 ? 281 MET A CB 1 ATOM 2331 C CG . MET A 1 281 ? -27.546 -14.431 -22.904 1.00 27.42 ? 281 MET A CG 1 ATOM 2332 S SD . MET A 1 281 ? -28.166 -14.984 -24.513 1.00 30.50 ? 281 MET A SD 1 ATOM 2333 C CE . MET A 1 281 ? -29.561 -13.855 -24.726 1.00 29.02 ? 281 MET A CE 1 ATOM 2334 N N . ALA A 1 282 ? -26.506 -16.667 -20.127 1.00 25.11 ? 282 ALA A N 1 ATOM 2335 C CA . ALA A 1 282 ? -25.220 -17.365 -19.839 1.00 25.32 ? 282 ALA A CA 1 ATOM 2336 C C . ALA A 1 282 ? -25.349 -18.892 -19.844 1.00 25.98 ? 282 ALA A C 1 ATOM 2337 O O . ALA A 1 282 ? -24.527 -19.606 -20.460 1.00 25.13 ? 282 ALA A O 1 ATOM 2338 C CB . ALA A 1 282 ? -24.629 -16.903 -18.511 1.00 24.42 ? 282 ALA A CB 1 ATOM 2339 N N . MET A 1 283 ? -26.379 -19.397 -19.168 1.00 26.04 ? 283 MET A N 1 ATOM 2340 C CA . MET A 1 283 ? -26.620 -20.847 -19.175 1.00 27.10 ? 283 MET A CA 1 ATOM 2341 C C . MET A 1 283 ? -26.871 -21.378 -20.584 1.00 26.90 ? 283 MET A C 1 ATOM 2342 O O . MET A 1 283 ? -26.285 -22.394 -20.979 1.00 27.63 ? 283 MET A O 1 ATOM 2343 C CB . MET A 1 283 ? -27.774 -21.203 -18.245 1.00 27.28 ? 283 MET A CB 1 ATOM 2344 C CG . MET A 1 283 ? -27.375 -21.092 -16.781 1.00 29.52 ? 283 MET A CG 1 ATOM 2345 S SD . MET A 1 283 ? -28.664 -21.630 -15.653 1.00 37.38 ? 283 MET A SD 1 ATOM 2346 C CE . MET A 1 283 ? -29.800 -20.274 -15.816 1.00 34.03 ? 283 MET A CE 1 ATOM 2347 N N . GLY A 1 284 ? -27.715 -20.679 -21.345 1.00 26.42 ? 284 GLY A N 1 ATOM 2348 C CA . GLY A 1 284 ? -28.065 -21.094 -22.714 1.00 26.27 ? 284 GLY A CA 1 ATOM 2349 C C . GLY A 1 284 ? -26.844 -21.083 -23.619 1.00 26.65 ? 284 GLY A C 1 ATOM 2350 O O . GLY A 1 284 ? -26.644 -21.992 -24.434 1.00 26.64 ? 284 GLY A O 1 ATOM 2351 N N . LEU A 1 285 ? -26.029 -20.044 -23.471 1.00 25.70 ? 285 LEU A N 1 ATOM 2352 C CA . LEU A 1 285 ? -24.816 -19.899 -24.258 1.00 26.46 ? 285 LEU A CA 1 ATOM 2353 C C . LEU A 1 285 ? -23.813 -21.010 -23.935 1.00 26.73 ? 285 LEU A C 1 ATOM 2354 O O . LEU A 1 285 ? -23.114 -21.500 -24.833 1.00 26.42 ? 285 LEU A O 1 ATOM 2355 C CB . LEU A 1 285 ? -24.205 -18.521 -24.006 1.00 25.86 ? 285 LEU A CB 1 ATOM 2356 C CG . LEU A 1 285 ? -24.200 -17.345 -24.988 1.00 26.51 ? 285 LEU A CG 1 ATOM 2357 C CD1 . LEU A 1 285 ? -25.105 -17.453 -26.182 1.00 24.01 ? 285 LEU A CD1 1 ATOM 2358 C CD2 . LEU A 1 285 ? -24.434 -16.061 -24.215 1.00 25.76 ? 285 LEU A CD2 1 ATOM 2359 N N . ARG A 1 286 ? -23.754 -21.421 -22.668 1.00 27.41 ? 286 ARG A N 1 ATOM 2360 C CA . ARG A 1 286 ? -22.913 -22.562 -22.264 1.00 28.00 ? 286 ARG A CA 1 ATOM 2361 C C . ARG A 1 286 ? -23.368 -23.888 -22.906 1.00 28.42 ? 286 ARG A C 1 ATOM 2362 O O . ARG A 1 286 ? -22.535 -24.721 -23.270 1.00 28.23 ? 286 ARG A O 1 ATOM 2363 C CB . ARG A 1 286 ? -22.882 -22.729 -20.747 1.00 28.04 ? 286 ARG A CB 1 ATOM 2364 C CG . ARG A 1 286 ? -21.937 -21.800 -19.976 1.00 28.76 ? 286 ARG A CG 1 ATOM 2365 C CD . ARG A 1 286 ? -21.201 -22.620 -18.903 1.00 28.64 ? 286 ARG A CD 1 ATOM 2366 N NE . ARG A 1 286 ? -19.949 -23.105 -19.440 1.00 31.24 ? 286 ARG A NE 1 ATOM 2367 C CZ . ARG A 1 286 ? -19.248 -24.149 -19.016 1.00 32.72 ? 286 ARG A CZ 1 ATOM 2368 N NH1 . ARG A 1 286 ? -19.649 -24.918 -18.008 1.00 31.84 ? 286 ARG A NH1 1 ATOM 2369 N NH2 . ARG A 1 286 ? -18.107 -24.420 -19.635 1.00 35.82 ? 286 ARG A NH2 1 ATOM 2370 N N . ILE A 1 287 ? -24.685 -24.079 -23.030 1.00 28.36 ? 287 ILE A N 1 ATOM 2371 C CA . ILE A 1 287 ? -25.243 -25.243 -23.731 1.00 28.76 ? 287 ILE A CA 1 ATOM 2372 C C . ILE A 1 287 ? -24.905 -25.217 -25.223 1.00 28.18 ? 287 ILE A C 1 ATOM 2373 O O . ILE A 1 287 ? -24.482 -26.226 -25.783 1.00 28.15 ? 287 ILE A O 1 ATOM 2374 C CB . ILE A 1 287 ? -26.791 -25.342 -23.578 1.00 28.86 ? 287 ILE A CB 1 ATOM 2375 C CG1 . ILE A 1 287 ? -27.226 -25.320 -22.100 1.00 29.81 ? 287 ILE A CG1 1 ATOM 2376 C CG2 . ILE A 1 287 ? -27.344 -26.572 -24.336 1.00 30.70 ? 287 ILE A CG2 1 ATOM 2377 C CD1 . ILE A 1 287 ? -26.818 -26.539 -21.274 1.00 32.24 ? 287 ILE A CD1 1 ATOM 2378 N N . LYS A 1 288 ? -25.117 -24.069 -25.864 1.00 27.89 ? 288 LYS A N 1 ATOM 2379 C CA . LYS A 1 288 ? -24.876 -23.931 -27.296 1.00 27.83 ? 288 LYS A CA 1 ATOM 2380 C C . LYS A 1 288 ? -23.390 -23.985 -27.671 1.00 27.59 ? 288 LYS A C 1 ATOM 2381 O O . LYS A 1 288 ? -23.062 -24.474 -28.748 1.00 26.90 ? 288 LYS A O 1 ATOM 2382 C CB . LYS A 1 288 ? -25.428 -22.615 -27.812 1.00 28.23 ? 288 LYS A CB 1 ATOM 2383 C CG . LYS A 1 288 ? -26.923 -22.539 -28.033 1.00 30.45 ? 288 LYS A CG 1 ATOM 2384 C CD . LYS A 1 288 ? -27.206 -21.352 -28.926 1.00 33.78 ? 288 LYS A CD 1 ATOM 2385 C CE . LYS A 1 288 ? -28.185 -20.384 -28.283 1.00 37.07 ? 288 LYS A CE 1 ATOM 2386 N NZ . LYS A 1 288 ? -29.548 -20.963 -28.196 1.00 39.02 ? 288 LYS A NZ 1 ATOM 2387 N N . PHE A 1 289 ? -22.513 -23.452 -26.804 1.00 26.95 ? 289 PHE A N 1 ATOM 2388 C CA . PHE A 1 289 ? -21.070 -23.397 -27.077 1.00 26.75 ? 289 PHE A CA 1 ATOM 2389 C C . PHE A 1 289 ? -20.209 -23.836 -25.881 1.00 26.71 ? 289 PHE A C 1 ATOM 2390 O O . PHE A 1 289 ? -19.464 -23.004 -25.332 1.00 25.81 ? 289 PHE A O 1 ATOM 2391 C CB . PHE A 1 289 ? -20.656 -21.963 -27.460 1.00 26.93 ? 289 PHE A CB 1 ATOM 2392 C CG . PHE A 1 289 ? -21.437 -21.385 -28.591 1.00 27.48 ? 289 PHE A CG 1 ATOM 2393 C CD1 . PHE A 1 289 ? -21.002 -21.551 -29.907 1.00 28.53 ? 289 PHE A CD1 1 ATOM 2394 C CD2 . PHE A 1 289 ? -22.597 -20.665 -28.353 1.00 27.23 ? 289 PHE A CD2 1 ATOM 2395 C CE1 . PHE A 1 289 ? -21.714 -21.012 -30.957 1.00 28.95 ? 289 PHE A CE1 1 ATOM 2396 C CE2 . PHE A 1 289 ? -23.318 -20.118 -29.399 1.00 26.76 ? 289 PHE A CE2 1 ATOM 2397 C CZ . PHE A 1 289 ? -22.888 -20.291 -30.701 1.00 27.75 ? 289 PHE A CZ 1 ATOM 2398 N N . PRO A 1 290 ? -20.277 -25.137 -25.483 1.00 27.02 ? 290 PRO A N 1 ATOM 2399 C CA . PRO A 1 290 ? -19.574 -25.539 -24.255 1.00 26.90 ? 290 PRO A CA 1 ATOM 2400 C C . PRO A 1 290 ? -18.059 -25.378 -24.379 1.00 26.98 ? 290 PRO A C 1 ATOM 2401 O O . PRO A 1 290 ? -17.367 -25.217 -23.380 1.00 27.12 ? 290 PRO A O 1 ATOM 2402 C CB . PRO A 1 290 ? -19.962 -27.013 -24.081 1.00 27.62 ? 290 PRO A CB 1 ATOM 2403 C CG . PRO A 1 290 ? -20.296 -27.484 -25.474 1.00 27.91 ? 290 PRO A CG 1 ATOM 2404 C CD . PRO A 1 290 ? -20.913 -26.287 -26.162 1.00 26.89 ? 290 PRO A CD 1 ATOM 2405 N N . THR A 1 291 ? -17.569 -25.333 -25.607 1.00 26.68 ? 291 THR A N 1 ATOM 2406 C CA . THR A 1 291 ? -16.147 -25.274 -25.874 1.00 27.28 ? 291 THR A CA 1 ATOM 2407 C C . THR A 1 291 ? -15.586 -23.829 -25.986 1.00 26.93 ? 291 THR A C 1 ATOM 2408 O O . THR A 1 291 ? -14.358 -23.622 -25.969 1.00 27.18 ? 291 THR A O 1 ATOM 2409 C CB . THR A 1 291 ? -15.868 -26.115 -27.150 1.00 27.42 ? 291 THR A CB 1 ATOM 2410 O OG1 . THR A 1 291 ? -14.747 -26.970 -26.917 1.00 32.88 ? 291 THR A OG1 1 ATOM 2411 C CG2 . THR A 1 291 ? -15.665 -25.260 -28.381 1.00 26.26 ? 291 THR A CG2 1 ATOM 2412 N N . VAL A 1 292 ? -16.491 -22.851 -26.071 1.00 25.69 ? 292 VAL A N 1 ATOM 2413 C CA . VAL A 1 292 ? -16.164 -21.446 -26.288 1.00 25.23 ? 292 VAL A CA 1 ATOM 2414 C C . VAL A 1 292 ? -16.521 -20.540 -25.078 1.00 24.21 ? 292 VAL A C 1 ATOM 2415 O O . VAL A 1 292 ? -15.721 -19.689 -24.697 1.00 23.52 ? 292 VAL A O 1 ATOM 2416 C CB . VAL A 1 292 ? -16.841 -20.888 -27.573 1.00 25.75 ? 292 VAL A CB 1 ATOM 2417 C CG1 . VAL A 1 292 ? -16.369 -19.487 -27.879 1.00 25.82 ? 292 VAL A CG1 1 ATOM 2418 C CG2 . VAL A 1 292 ? -16.577 -21.798 -28.788 1.00 26.49 ? 292 VAL A CG2 1 ATOM 2419 N N . VAL A 1 293 ? -17.705 -20.722 -24.491 1.00 22.52 ? 293 VAL A N 1 ATOM 2420 C CA . VAL A 1 293 ? -18.149 -19.898 -23.376 1.00 21.75 ? 293 VAL A CA 1 ATOM 2421 C C . VAL A 1 293 ? -17.763 -20.537 -22.021 1.00 22.15 ? 293 VAL A C 1 ATOM 2422 O O . VAL A 1 293 ? -18.294 -21.570 -21.660 1.00 22.37 ? 293 VAL A O 1 ATOM 2423 C CB . VAL A 1 293 ? -19.662 -19.661 -23.460 1.00 22.25 ? 293 VAL A CB 1 ATOM 2424 C CG1 . VAL A 1 293 ? -20.182 -18.836 -22.255 1.00 22.49 ? 293 VAL A CG1 1 ATOM 2425 C CG2 . VAL A 1 293 ? -19.984 -18.993 -24.784 1.00 20.19 ? 293 VAL A CG2 1 ATOM 2426 N N . ALA A 1 294 ? -16.821 -19.919 -21.305 1.00 20.84 ? 294 ALA A N 1 ATOM 2427 C CA . ALA A 1 294 ? -16.360 -20.409 -20.005 1.00 20.74 ? 294 ALA A CA 1 ATOM 2428 C C . ALA A 1 294 ? -17.329 -20.168 -18.836 1.00 20.22 ? 294 ALA A C 1 ATOM 2429 O O . ALA A 1 294 ? -17.351 -20.943 -17.886 1.00 19.51 ? 294 ALA A O 1 ATOM 2430 C CB . ALA A 1 294 ? -14.963 -19.840 -19.676 1.00 21.20 ? 294 ALA A CB 1 ATOM 2431 N N . GLY A 1 295 ? -18.113 -19.098 -18.893 1.00 19.10 ? 295 GLY A N 1 ATOM 2432 C CA . GLY A 1 295 ? -19.017 -18.770 -17.786 1.00 18.66 ? 295 GLY A CA 1 ATOM 2433 C C . GLY A 1 295 ? -19.346 -17.281 -17.752 1.00 18.87 ? 295 GLY A C 1 ATOM 2434 O O . GLY A 1 295 ? -19.374 -16.636 -18.808 1.00 19.19 ? 295 GLY A O 1 ATOM 2435 N N . PHE A 1 296 ? -19.571 -16.739 -16.543 1.00 18.09 ? 296 PHE A N 1 ATOM 2436 C CA . PHE A 1 296 ? -20.179 -15.404 -16.373 1.00 18.24 ? 296 PHE A CA 1 ATOM 2437 C C . PHE A 1 296 ? -19.460 -14.482 -15.366 1.00 17.92 ? 296 PHE A C 1 ATOM 2438 O O . PHE A 1 296 ? -18.875 -14.953 -14.409 1.00 17.60 ? 296 PHE A O 1 ATOM 2439 C CB . PHE A 1 296 ? -21.634 -15.590 -15.909 1.00 18.33 ? 296 PHE A CB 1 ATOM 2440 C CG . PHE A 1 296 ? -22.411 -14.307 -15.791 1.00 18.41 ? 296 PHE A CG 1 ATOM 2441 C CD1 . PHE A 1 296 ? -22.668 -13.748 -14.541 1.00 18.75 ? 296 PHE A CD1 1 ATOM 2442 C CD2 . PHE A 1 296 ? -22.892 -13.667 -16.930 1.00 19.14 ? 296 PHE A CD2 1 ATOM 2443 C CE1 . PHE A 1 296 ? -23.402 -12.551 -14.435 1.00 23.00 ? 296 PHE A CE1 1 ATOM 2444 C CE2 . PHE A 1 296 ? -23.619 -12.464 -16.834 1.00 19.37 ? 296 PHE A CE2 1 ATOM 2445 C CZ . PHE A 1 296 ? -23.875 -11.916 -15.596 1.00 19.79 ? 296 PHE A CZ 1 ATOM 2446 N N . ASP A 1 297 ? -19.566 -13.161 -15.559 1.00 18.17 ? 297 ASP A N 1 ATOM 2447 C CA . ASP A 1 297 ? -18.947 -12.187 -14.650 1.00 18.21 ? 297 ASP A CA 1 ATOM 2448 C C . ASP A 1 297 ? -19.777 -10.907 -14.663 1.00 18.93 ? 297 ASP A C 1 ATOM 2449 O O . ASP A 1 297 ? -20.533 -10.665 -15.608 1.00 18.41 ? 297 ASP A O 1 ATOM 2450 C CB . ASP A 1 297 ? -17.513 -11.879 -15.150 1.00 17.38 ? 297 ASP A CB 1 ATOM 2451 C CG . ASP A 1 297 ? -16.705 -10.922 -14.230 1.00 18.28 ? 297 ASP A CG 1 ATOM 2452 O OD1 . ASP A 1 297 ? -17.102 -10.600 -13.075 1.00 18.54 ? 297 ASP A OD1 1 ATOM 2453 O OD2 . ASP A 1 297 ? -15.591 -10.516 -14.674 1.00 19.04 ? 297 ASP A OD2 1 ATOM 2454 N N . LEU A 1 298 ? -19.591 -10.082 -13.636 1.00 19.07 ? 298 LEU A N 1 ATOM 2455 C CA . LEU A 1 298 ? -20.241 -8.782 -13.513 1.00 20.13 ? 298 LEU A CA 1 ATOM 2456 C C . LEU A 1 298 ? -19.172 -7.698 -13.556 1.00 20.33 ? 298 LEU A C 1 ATOM 2457 O O . LEU A 1 298 ? -18.171 -7.790 -12.841 1.00 21.70 ? 298 LEU A O 1 ATOM 2458 C CB . LEU A 1 298 ? -21.021 -8.730 -12.190 1.00 20.25 ? 298 LEU A CB 1 ATOM 2459 C CG . LEU A 1 298 ? -22.266 -9.626 -12.177 1.00 21.30 ? 298 LEU A CG 1 ATOM 2460 C CD1 . LEU A 1 298 ? -22.767 -9.885 -10.767 1.00 20.55 ? 298 LEU A CD1 1 ATOM 2461 C CD2 . LEU A 1 298 ? -23.355 -9.002 -13.023 1.00 22.27 ? 298 LEU A CD2 1 ATOM 2462 N N . VAL A 1 299 ? -19.340 -6.711 -14.432 1.00 20.69 ? 299 VAL A N 1 ATOM 2463 C CA . VAL A 1 299 ? -18.296 -5.701 -14.673 1.00 20.48 ? 299 VAL A CA 1 ATOM 2464 C C . VAL A 1 299 ? -18.792 -4.283 -14.409 1.00 21.38 ? 299 VAL A C 1 ATOM 2465 O O . VAL A 1 299 ? -19.984 -4.077 -14.172 1.00 20.97 ? 299 VAL A O 1 ATOM 2466 C CB . VAL A 1 299 ? -17.693 -5.826 -16.101 1.00 20.34 ? 299 VAL A CB 1 ATOM 2467 C CG1 . VAL A 1 299 ? -17.078 -7.204 -16.269 1.00 19.48 ? 299 VAL A CG1 1 ATOM 2468 C CG2 . VAL A 1 299 ? -18.742 -5.542 -17.207 1.00 19.10 ? 299 VAL A CG2 1 ATOM 2469 N N . GLY A 1 300 ? -17.877 -3.311 -14.450 1.00 21.14 ? 300 GLY A N 1 ATOM 2470 C CA . GLY A 1 300 ? -18.207 -1.914 -14.142 1.00 21.38 ? 300 GLY A CA 1 ATOM 2471 C C . GLY A 1 300 ? -17.593 -1.447 -12.824 1.00 21.67 ? 300 GLY A C 1 ATOM 2472 O O . GLY A 1 300 ? -16.912 -2.223 -12.130 1.00 21.52 ? 300 GLY A O 1 ATOM 2473 N N . HIS A 1 301 ? -17.850 -0.186 -12.480 1.00 21.51 ? 301 HIS A N 1 ATOM 2474 C CA . HIS A 1 301 ? -17.255 0.461 -11.308 1.00 22.10 ? 301 HIS A CA 1 ATOM 2475 C C . HIS A 1 301 ? -17.783 -0.201 -10.038 1.00 21.21 ? 301 HIS A C 1 ATOM 2476 O O . HIS A 1 301 ? -18.985 -0.113 -9.714 1.00 21.19 ? 301 HIS A O 1 ATOM 2477 C CB . HIS A 1 301 ? -17.548 1.967 -11.315 1.00 21.87 ? 301 HIS A CB 1 ATOM 2478 C CG . HIS A 1 301 ? -16.703 2.761 -10.355 1.00 24.26 ? 301 HIS A CG 1 ATOM 2479 N ND1 . HIS A 1 301 ? -15.551 2.265 -9.773 1.00 24.12 ? 301 HIS A ND1 1 ATOM 2480 C CD2 . HIS A 1 301 ? -16.820 4.038 -9.914 1.00 24.76 ? 301 HIS A CD2 1 ATOM 2481 C CE1 . HIS A 1 301 ? -15.020 3.188 -8.990 1.00 24.42 ? 301 HIS A CE1 1 ATOM 2482 N NE2 . HIS A 1 301 ? -15.759 4.279 -9.071 1.00 26.16 ? 301 HIS A NE2 1 ATOM 2483 N N . GLU A 1 302 ? -16.896 -0.889 -9.341 1.00 20.49 ? 302 GLU A N 1 ATOM 2484 C CA . GLU A 1 302 ? -17.319 -1.746 -8.234 1.00 20.55 ? 302 GLU A CA 1 ATOM 2485 C C . GLU A 1 302 ? -17.729 -0.955 -6.989 1.00 20.78 ? 302 GLU A C 1 ATOM 2486 O O . GLU A 1 302 ? -18.665 -1.342 -6.302 1.00 21.15 ? 302 GLU A O 1 ATOM 2487 C CB . GLU A 1 302 ? -16.242 -2.774 -7.893 1.00 20.61 ? 302 GLU A CB 1 ATOM 2488 C CG . GLU A 1 302 ? -16.750 -3.939 -6.967 1.00 18.05 ? 302 GLU A CG 1 ATOM 2489 C CD . GLU A 1 302 ? -15.649 -4.952 -6.585 1.00 20.39 ? 302 GLU A CD 1 ATOM 2490 O OE1 . GLU A 1 302 ? -14.551 -4.931 -7.216 1.00 20.28 ? 302 GLU A OE1 1 ATOM 2491 O OE2 . GLU A 1 302 ? -15.887 -5.768 -5.652 1.00 17.60 ? 302 GLU A OE2 1 ATOM 2492 N N . ASP A 1 303 ? -17.057 0.162 -6.720 1.00 21.32 ? 303 ASP A N 1 ATOM 2493 C CA . ASP A 1 303 ? -17.419 1.023 -5.590 1.00 22.89 ? 303 ASP A CA 1 ATOM 2494 C C . ASP A 1 303 ? -18.857 1.591 -5.658 1.00 23.38 ? 303 ASP A C 1 ATOM 2495 O O . ASP A 1 303 ? -19.497 1.760 -4.627 1.00 23.94 ? 303 ASP A O 1 ATOM 2496 C CB . ASP A 1 303 ? -16.444 2.205 -5.467 1.00 23.59 ? 303 ASP A CB 1 ATOM 2497 C CG . ASP A 1 303 ? -15.120 1.840 -4.793 1.00 24.69 ? 303 ASP A CG 1 ATOM 2498 O OD1 . ASP A 1 303 ? -14.902 0.679 -4.388 1.00 28.02 ? 303 ASP A OD1 1 ATOM 2499 O OD2 . ASP A 1 303 ? -14.276 2.747 -4.648 1.00 25.30 ? 303 ASP A OD2 1 ATOM 2500 N N . THR A 1 304 ? -19.343 1.880 -6.865 1.00 23.70 ? 304 THR A N 1 ATOM 2501 C CA . THR A 1 304 ? -20.607 2.600 -7.062 1.00 24.20 ? 304 THR A CA 1 ATOM 2502 C C . THR A 1 304 ? -21.771 1.732 -7.559 1.00 24.42 ? 304 THR A C 1 ATOM 2503 O O . THR A 1 304 ? -22.913 2.186 -7.600 1.00 25.18 ? 304 THR A O 1 ATOM 2504 C CB . THR A 1 304 ? -20.413 3.742 -8.070 1.00 23.65 ? 304 THR A CB 1 ATOM 2505 O OG1 . THR A 1 304 ? -19.883 3.202 -9.279 1.00 24.49 ? 304 THR A OG1 1 ATOM 2506 C CG2 . THR A 1 304 ? -19.448 4.813 -7.536 1.00 24.42 ? 304 THR A CG2 1 ATOM 2507 N N . GLY A 1 305 ? -21.487 0.499 -7.964 1.00 24.33 ? 305 GLY A N 1 ATOM 2508 C CA . GLY A 1 305 ? -22.520 -0.407 -8.447 1.00 23.91 ? 305 GLY A CA 1 ATOM 2509 C C . GLY A 1 305 ? -23.021 -1.358 -7.380 1.00 24.20 ? 305 GLY A C 1 ATOM 2510 O O . GLY A 1 305 ? -22.692 -1.216 -6.200 1.00 24.79 ? 305 GLY A O 1 ATOM 2511 N N . HIS A 1 306 ? -23.795 -2.351 -7.801 1.00 23.03 ? 306 HIS A N 1 ATOM 2512 C CA . HIS A 1 306 ? -24.349 -3.346 -6.898 1.00 23.23 ? 306 HIS A CA 1 ATOM 2513 C C . HIS A 1 306 ? -23.298 -4.346 -6.429 1.00 22.96 ? 306 HIS A C 1 ATOM 2514 O O . HIS A 1 306 ? -22.350 -4.660 -7.167 1.00 22.27 ? 306 HIS A O 1 ATOM 2515 C CB . HIS A 1 306 ? -25.442 -4.120 -7.610 1.00 23.60 ? 306 HIS A CB 1 ATOM 2516 C CG . HIS A 1 306 ? -26.756 -3.417 -7.651 1.00 25.49 ? 306 HIS A CG 1 ATOM 2517 N ND1 . HIS A 1 306 ? -27.245 -2.811 -8.790 1.00 28.81 ? 306 HIS A ND1 1 ATOM 2518 C CD2 . HIS A 1 306 ? -27.691 -3.235 -6.692 1.00 27.77 ? 306 HIS A CD2 1 ATOM 2519 C CE1 . HIS A 1 306 ? -28.429 -2.285 -8.527 1.00 29.62 ? 306 HIS A CE1 1 ATOM 2520 N NE2 . HIS A 1 306 ? -28.724 -2.534 -7.261 1.00 29.57 ? 306 HIS A NE2 1 ATOM 2521 N N . SER A 1 307 ? -23.483 -4.854 -5.212 1.00 22.82 ? 307 SER A N 1 ATOM 2522 C CA . SER A 1 307 ? -22.639 -5.943 -4.669 1.00 23.16 ? 307 SER A CA 1 ATOM 2523 C C . SER A 1 307 ? -23.113 -7.305 -5.162 1.00 23.51 ? 307 SER A C 1 ATOM 2524 O O . SER A 1 307 ? -24.260 -7.440 -5.635 1.00 23.47 ? 307 SER A O 1 ATOM 2525 C CB . SER A 1 307 ? -22.685 -5.924 -3.140 1.00 23.94 ? 307 SER A CB 1 ATOM 2526 O OG . SER A 1 307 ? -23.989 -6.304 -2.671 1.00 22.31 ? 307 SER A OG 1 ATOM 2527 N N . LEU A 1 308 ? -22.253 -8.323 -5.017 1.00 22.85 ? 308 LEU A N 1 ATOM 2528 C CA . LEU A 1 308 ? -22.630 -9.698 -5.316 1.00 22.73 ? 308 LEU A CA 1 ATOM 2529 C C . LEU A 1 308 ? -23.782 -10.147 -4.393 1.00 24.03 ? 308 LEU A C 1 ATOM 2530 O O . LEU A 1 308 ? -24.704 -10.852 -4.835 1.00 23.28 ? 308 LEU A O 1 ATOM 2531 C CB . LEU A 1 308 ? -21.421 -10.649 -5.200 1.00 21.83 ? 308 LEU A CB 1 ATOM 2532 C CG . LEU A 1 308 ? -20.260 -10.385 -6.182 1.00 20.11 ? 308 LEU A CG 1 ATOM 2533 C CD1 . LEU A 1 308 ? -19.106 -11.386 -6.000 1.00 21.01 ? 308 LEU A CD1 1 ATOM 2534 C CD2 . LEU A 1 308 ? -20.727 -10.400 -7.619 1.00 19.17 ? 308 LEU A CD2 1 ATOM 2535 N N . HIS A 1 309 ? -23.728 -9.733 -3.122 1.00 24.34 ? 309 HIS A N 1 ATOM 2536 C CA . HIS A 1 309 ? -24.828 -10.006 -2.202 1.00 25.92 ? 309 HIS A CA 1 ATOM 2537 C C . HIS A 1 309 ? -26.155 -9.467 -2.730 1.00 25.33 ? 309 HIS A C 1 ATOM 2538 O O . HIS A 1 309 ? -27.115 -10.191 -2.723 1.00 26.06 ? 309 HIS A O 1 ATOM 2539 C CB . HIS A 1 309 ? -24.581 -9.477 -0.786 1.00 26.44 ? 309 HIS A CB 1 ATOM 2540 C CG . HIS A 1 309 ? -25.583 -9.980 0.214 1.00 30.17 ? 309 HIS A CG 1 ATOM 2541 N ND1 . HIS A 1 309 ? -25.506 -11.237 0.777 1.00 33.47 ? 309 HIS A ND1 1 ATOM 2542 C CD2 . HIS A 1 309 ? -26.704 -9.410 0.720 1.00 33.01 ? 309 HIS A CD2 1 ATOM 2543 C CE1 . HIS A 1 309 ? -26.522 -11.413 1.605 1.00 34.59 ? 309 HIS A CE1 1 ATOM 2544 N NE2 . HIS A 1 309 ? -27.264 -10.319 1.588 1.00 34.87 ? 309 HIS A NE2 1 ATOM 2545 N N . ASP A 1 310 ? -26.190 -8.218 -3.196 1.00 26.24 ? 310 ASP A N 1 ATOM 2546 C CA . ASP A 1 310 ? -27.360 -7.629 -3.847 1.00 26.18 ? 310 ASP A CA 1 ATOM 2547 C C . ASP A 1 310 ? -27.962 -8.514 -4.938 1.00 26.58 ? 310 ASP A C 1 ATOM 2548 O O . ASP A 1 310 ? -29.186 -8.496 -5.165 1.00 26.06 ? 310 ASP A O 1 ATOM 2549 C CB . ASP A 1 310 ? -27.016 -6.291 -4.510 1.00 26.80 ? 310 ASP A CB 1 ATOM 2550 C CG . ASP A 1 310 ? -26.744 -5.183 -3.519 1.00 28.01 ? 310 ASP A CG 1 ATOM 2551 O OD1 . ASP A 1 310 ? -27.050 -5.325 -2.310 1.00 30.03 ? 310 ASP A OD1 1 ATOM 2552 O OD2 . ASP A 1 310 ? -26.212 -4.155 -3.970 1.00 29.08 ? 310 ASP A OD2 1 ATOM 2553 N N . TYR A 1 311 ? -27.098 -9.241 -5.642 1.00 25.54 ? 311 TYR A N 1 ATOM 2554 C CA . TYR A 1 311 ? -27.519 -10.084 -6.745 1.00 25.91 ? 311 TYR A CA 1 ATOM 2555 C C . TYR A 1 311 ? -27.763 -11.539 -6.355 1.00 26.04 ? 311 TYR A C 1 ATOM 2556 O O . TYR A 1 311 ? -27.918 -12.393 -7.242 1.00 25.14 ? 311 TYR A O 1 ATOM 2557 C CB . TYR A 1 311 ? -26.455 -10.059 -7.835 1.00 25.52 ? 311 TYR A CB 1 ATOM 2558 C CG . TYR A 1 311 ? -26.387 -8.773 -8.635 1.00 26.21 ? 311 TYR A CG 1 ATOM 2559 C CD1 . TYR A 1 311 ? -27.536 -8.226 -9.211 1.00 25.01 ? 311 TYR A CD1 1 ATOM 2560 C CD2 . TYR A 1 311 ? -25.165 -8.138 -8.868 1.00 24.58 ? 311 TYR A CD2 1 ATOM 2561 C CE1 . TYR A 1 311 ? -27.493 -7.059 -9.970 1.00 23.92 ? 311 TYR A CE1 1 ATOM 2562 C CE2 . TYR A 1 311 ? -25.105 -6.959 -9.652 1.00 22.03 ? 311 TYR A CE2 1 ATOM 2563 C CZ . TYR A 1 311 ? -26.281 -6.432 -10.194 1.00 24.27 ? 311 TYR A CZ 1 ATOM 2564 O OH . TYR A 1 311 ? -26.262 -5.297 -10.976 1.00 20.32 ? 311 TYR A OH 1 ATOM 2565 N N . LYS A 1 312 ? -27.797 -11.832 -5.052 1.00 26.95 ? 312 LYS A N 1 ATOM 2566 C CA . LYS A 1 312 ? -27.843 -13.227 -4.601 1.00 29.24 ? 312 LYS A CA 1 ATOM 2567 C C . LYS A 1 312 ? -28.863 -14.069 -5.353 1.00 29.79 ? 312 LYS A C 1 ATOM 2568 O O . LYS A 1 312 ? -28.515 -15.138 -5.857 1.00 30.07 ? 312 LYS A O 1 ATOM 2569 C CB . LYS A 1 312 ? -28.087 -13.360 -3.098 1.00 30.13 ? 312 LYS A CB 1 ATOM 2570 C CG . LYS A 1 312 ? -27.670 -14.740 -2.539 1.00 32.88 ? 312 LYS A CG 1 ATOM 2571 C CD . LYS A 1 312 ? -27.832 -14.801 -1.005 1.00 38.91 ? 312 LYS A CD 1 ATOM 2572 C CE . LYS A 1 312 ? -29.260 -15.204 -0.597 1.00 41.86 ? 312 LYS A CE 1 ATOM 2573 N NZ . LYS A 1 312 ? -29.646 -14.712 0.774 1.00 44.75 ? 312 LYS A NZ 1 ATOM 2574 N N . GLU A 1 313 ? -30.097 -13.577 -5.458 1.00 30.22 ? 313 GLU A N 1 ATOM 2575 C CA . GLU A 1 313 ? -31.177 -14.392 -6.032 1.00 30.86 ? 313 GLU A CA 1 ATOM 2576 C C . GLU A 1 313 ? -30.946 -14.726 -7.510 1.00 30.19 ? 313 GLU A C 1 ATOM 2577 O O . GLU A 1 313 ? -31.263 -15.824 -7.938 1.00 30.06 ? 313 GLU A O 1 ATOM 2578 C CB . GLU A 1 313 ? -32.561 -13.758 -5.813 1.00 31.30 ? 313 GLU A CB 1 ATOM 2579 C CG . GLU A 1 313 ? -32.928 -13.510 -4.333 1.00 35.06 ? 313 GLU A CG 1 ATOM 2580 C CD . GLU A 1 313 ? -32.766 -14.760 -3.440 1.00 39.47 ? 313 GLU A CD 1 ATOM 2581 O OE1 . GLU A 1 313 ? -32.937 -15.900 -3.936 1.00 43.25 ? 313 GLU A OE1 1 ATOM 2582 O OE2 . GLU A 1 313 ? -32.472 -14.605 -2.231 1.00 41.14 ? 313 GLU A OE2 1 ATOM 2583 N N . ALA A 1 314 ? -30.401 -13.785 -8.285 1.00 29.58 ? 314 ALA A N 1 ATOM 2584 C CA . ALA A 1 314 ? -30.074 -14.075 -9.681 1.00 28.87 ? 314 ALA A CA 1 ATOM 2585 C C . ALA A 1 314 ? -28.908 -15.059 -9.780 1.00 28.87 ? 314 ALA A C 1 ATOM 2586 O O . ALA A 1 314 ? -28.980 -16.043 -10.531 1.00 28.59 ? 314 ALA A O 1 ATOM 2587 C CB . ALA A 1 314 ? -29.796 -12.798 -10.455 1.00 28.54 ? 314 ALA A CB 1 ATOM 2588 N N . LEU A 1 315 ? -27.848 -14.820 -9.006 1.00 28.77 ? 315 LEU A N 1 ATOM 2589 C CA . LEU A 1 315 ? -26.626 -15.661 -9.050 1.00 29.12 ? 315 LEU A CA 1 ATOM 2590 C C . LEU A 1 315 ? -26.839 -17.093 -8.555 1.00 29.73 ? 315 LEU A C 1 ATOM 2591 O O . LEU A 1 315 ? -26.076 -17.995 -8.873 1.00 29.72 ? 315 LEU A O 1 ATOM 2592 C CB . LEU A 1 315 ? -25.444 -14.980 -8.305 1.00 27.92 ? 315 LEU A CB 1 ATOM 2593 C CG . LEU A 1 315 ? -25.069 -13.600 -8.869 1.00 27.43 ? 315 LEU A CG 1 ATOM 2594 C CD1 . LEU A 1 315 ? -24.000 -12.888 -8.025 1.00 27.21 ? 315 LEU A CD1 1 ATOM 2595 C CD2 . LEU A 1 315 ? -24.642 -13.671 -10.352 1.00 24.30 ? 315 LEU A CD2 1 ATOM 2596 N N . MET A 1 316 ? -27.888 -17.291 -7.780 1.00 31.22 ? 316 MET A N 1 ATOM 2597 C CA . MET A 1 316 ? -28.246 -18.626 -7.299 1.00 32.82 ? 316 MET A CA 1 ATOM 2598 C C . MET A 1 316 ? -29.164 -19.428 -8.259 1.00 33.33 ? 316 MET A C 1 ATOM 2599 O O . MET A 1 316 ? -29.437 -20.608 -8.019 1.00 33.65 ? 316 MET A O 1 ATOM 2600 C CB . MET A 1 316 ? -28.882 -18.503 -5.910 1.00 33.30 ? 316 MET A CB 1 ATOM 2601 C CG . MET A 1 316 ? -27.891 -18.113 -4.819 1.00 36.11 ? 316 MET A CG 1 ATOM 2602 S SD . MET A 1 316 ? -26.579 -19.350 -4.675 1.00 41.39 ? 316 MET A SD 1 ATOM 2603 C CE . MET A 1 316 ? -27.548 -20.786 -4.169 1.00 42.41 ? 316 MET A CE 1 ATOM 2604 N N . ILE A 1 317 ? -29.628 -18.794 -9.339 1.00 34.08 ? 317 ILE A N 1 ATOM 2605 C CA . ILE A 1 317 ? -30.492 -19.475 -10.329 1.00 34.97 ? 317 ILE A CA 1 ATOM 2606 C C . ILE A 1 317 ? -29.920 -20.801 -10.868 1.00 36.12 ? 317 ILE A C 1 ATOM 2607 O O . ILE A 1 317 ? -30.599 -21.828 -10.783 1.00 36.15 ? 317 ILE A O 1 ATOM 2608 C CB . ILE A 1 317 ? -30.909 -18.546 -11.480 1.00 34.83 ? 317 ILE A CB 1 ATOM 2609 C CG1 . ILE A 1 317 ? -31.919 -17.525 -10.975 1.00 33.41 ? 317 ILE A CG1 1 ATOM 2610 C CG2 . ILE A 1 317 ? -31.468 -19.355 -12.669 1.00 35.36 ? 317 ILE A CG2 1 ATOM 2611 C CD1 . ILE A 1 317 ? -32.161 -16.367 -11.922 1.00 35.12 ? 317 ILE A CD1 1 ATOM 2612 N N . PRO A 1 318 ? -28.671 -20.797 -11.398 1.00 37.03 ? 318 PRO A N 1 ATOM 2613 C CA . PRO A 1 318 ? -28.144 -22.043 -11.957 1.00 37.76 ? 318 PRO A CA 1 ATOM 2614 C C . PRO A 1 318 ? -28.198 -23.192 -10.943 1.00 38.63 ? 318 PRO A C 1 ATOM 2615 O O . PRO A 1 318 ? -28.623 -24.294 -11.297 1.00 39.22 ? 318 PRO A O 1 ATOM 2616 C CB . PRO A 1 318 ? -26.693 -21.680 -12.314 1.00 37.71 ? 318 PRO A CB 1 ATOM 2617 C CG . PRO A 1 318 ? -26.745 -20.205 -12.570 1.00 37.35 ? 318 PRO A CG 1 ATOM 2618 C CD . PRO A 1 318 ? -27.699 -19.692 -11.533 1.00 36.99 ? 318 PRO A CD 1 ATOM 2619 N N . ALA A 1 319 ? -27.792 -22.922 -9.700 1.00 39.35 ? 319 ALA A N 1 ATOM 2620 C CA . ALA A 1 319 ? -27.866 -23.894 -8.598 1.00 40.29 ? 319 ALA A CA 1 ATOM 2621 C C . ALA A 1 319 ? -29.307 -24.328 -8.287 1.00 41.17 ? 319 ALA A C 1 ATOM 2622 O O . ALA A 1 319 ? -29.576 -25.516 -8.155 1.00 41.29 ? 319 ALA A O 1 ATOM 2623 C CB . ALA A 1 319 ? -27.202 -23.343 -7.357 1.00 40.05 ? 319 ALA A CB 1 ATOM 2624 N N . LYS A 1 320 ? -30.224 -23.365 -8.183 1.00 42.08 ? 320 LYS A N 1 ATOM 2625 C CA . LYS A 1 320 ? -31.656 -23.663 -8.019 1.00 42.83 ? 320 LYS A CA 1 ATOM 2626 C C . LYS A 1 320 ? -32.243 -24.464 -9.196 1.00 42.96 ? 320 LYS A C 1 ATOM 2627 O O . LYS A 1 320 ? -33.317 -25.036 -9.060 1.00 43.66 ? 320 LYS A O 1 ATOM 2628 C CB . LYS A 1 320 ? -32.476 -22.380 -7.798 1.00 42.88 ? 320 LYS A CB 1 ATOM 2629 C CG . LYS A 1 320 ? -32.239 -21.689 -6.450 1.00 44.21 ? 320 LYS A CG 1 ATOM 2630 C CD . LYS A 1 320 ? -33.006 -20.357 -6.305 1.00 47.08 ? 320 LYS A CD 1 ATOM 2631 C CE . LYS A 1 320 ? -32.611 -19.326 -7.384 1.00 48.21 ? 320 LYS A CE 1 ATOM 2632 N NZ . LYS A 1 320 ? -32.891 -17.918 -6.976 1.00 46.93 ? 320 LYS A NZ 1 ATOM 2633 N N . ASP A 1 321 ? -31.544 -24.505 -10.336 1.00 42.93 ? 321 ASP A N 1 ATOM 2634 C CA . ASP A 1 321 ? -31.958 -25.325 -11.491 1.00 42.56 ? 321 ASP A CA 1 ATOM 2635 C C . ASP A 1 321 ? -31.098 -26.570 -11.697 1.00 41.88 ? 321 ASP A C 1 ATOM 2636 O O . ASP A 1 321 ? -31.169 -27.205 -12.760 1.00 42.08 ? 321 ASP A O 1 ATOM 2637 C CB . ASP A 1 321 ? -31.949 -24.511 -12.785 1.00 42.73 ? 321 ASP A CB 1 ATOM 2638 C CG . ASP A 1 321 ? -32.941 -23.368 -12.767 1.00 44.85 ? 321 ASP A CG 1 ATOM 2639 O OD1 . ASP A 1 321 ? -33.502 -23.066 -11.686 1.00 47.47 ? 321 ASP A OD1 1 ATOM 2640 O OD2 . ASP A 1 321 ? -33.152 -22.764 -13.842 1.00 46.46 ? 321 ASP A OD2 1 ATOM 2641 N N . GLY A 1 322 ? -30.279 -26.909 -10.702 1.00 41.00 ? 322 GLY A N 1 ATOM 2642 C CA . GLY A 1 322 ? -29.375 -28.059 -10.801 1.00 39.84 ? 322 GLY A CA 1 ATOM 2643 C C . GLY A 1 322 ? -28.276 -27.921 -11.848 1.00 39.21 ? 322 GLY A C 1 ATOM 2644 O O . GLY A 1 322 ? -27.786 -28.918 -12.370 1.00 39.49 ? 322 GLY A O 1 ATOM 2645 N N . VAL A 1 323 ? -27.875 -26.690 -12.164 1.00 38.15 ? 323 VAL A N 1 ATOM 2646 C CA . VAL A 1 323 ? -26.834 -26.474 -13.177 1.00 36.58 ? 323 VAL A CA 1 ATOM 2647 C C . VAL A 1 323 ? -25.633 -25.755 -12.555 1.00 35.56 ? 323 VAL A C 1 ATOM 2648 O O . VAL A 1 323 ? -25.790 -24.871 -11.715 1.00 35.57 ? 323 VAL A O 1 ATOM 2649 C CB . VAL A 1 323 ? -27.400 -25.731 -14.431 1.00 37.19 ? 323 VAL A CB 1 ATOM 2650 C CG1 . VAL A 1 323 ? -26.294 -25.118 -15.305 1.00 36.76 ? 323 VAL A CG1 1 ATOM 2651 C CG2 . VAL A 1 323 ? -28.257 -26.682 -15.272 1.00 37.56 ? 323 VAL A CG2 1 ATOM 2652 N N . LYS A 1 324 ? -24.435 -26.184 -12.935 1.00 33.83 ? 324 LYS A N 1 ATOM 2653 C CA . LYS A 1 324 ? -23.219 -25.451 -12.621 1.00 31.94 ? 324 LYS A CA 1 ATOM 2654 C C . LYS A 1 324 ? -23.000 -24.338 -13.673 1.00 29.94 ? 324 LYS A C 1 ATOM 2655 O O . LYS A 1 324 ? -22.813 -24.634 -14.853 1.00 29.97 ? 324 LYS A O 1 ATOM 2656 C CB . LYS A 1 324 ? -22.038 -26.419 -12.640 1.00 32.18 ? 324 LYS A CB 1 ATOM 2657 N N . LEU A 1 325 ? -23.064 -23.072 -13.262 1.00 27.22 ? 325 LEU A N 1 ATOM 2658 C CA . LEU A 1 325 ? -22.564 -21.969 -14.122 1.00 24.53 ? 325 LEU A CA 1 ATOM 2659 C C . LEU A 1 325 ? -21.256 -21.400 -13.540 1.00 23.16 ? 325 LEU A C 1 ATOM 2660 O O . LEU A 1 325 ? -21.280 -20.763 -12.474 1.00 22.65 ? 325 LEU A O 1 ATOM 2661 C CB . LEU A 1 325 ? -23.615 -20.859 -14.308 1.00 23.95 ? 325 LEU A CB 1 ATOM 2662 C CG . LEU A 1 325 ? -23.244 -19.548 -15.037 1.00 23.95 ? 325 LEU A CG 1 ATOM 2663 C CD1 . LEU A 1 325 ? -22.904 -19.762 -16.524 1.00 19.70 ? 325 LEU A CD1 1 ATOM 2664 C CD2 . LEU A 1 325 ? -24.314 -18.426 -14.874 1.00 22.38 ? 325 LEU A CD2 1 ATOM 2665 N N . PRO A 1 326 ? -20.105 -21.648 -14.215 1.00 22.03 ? 326 PRO A N 1 ATOM 2666 C CA . PRO A 1 326 ? -18.845 -21.110 -13.694 1.00 20.86 ? 326 PRO A CA 1 ATOM 2667 C C . PRO A 1 326 ? -18.845 -19.575 -13.650 1.00 20.22 ? 326 PRO A C 1 ATOM 2668 O O . PRO A 1 326 ? -19.345 -18.917 -14.579 1.00 21.05 ? 326 PRO A O 1 ATOM 2669 C CB . PRO A 1 326 ? -17.803 -21.631 -14.699 1.00 21.03 ? 326 PRO A CB 1 ATOM 2670 C CG . PRO A 1 326 ? -18.444 -22.887 -15.249 1.00 21.42 ? 326 PRO A CG 1 ATOM 2671 C CD . PRO A 1 326 ? -19.873 -22.486 -15.407 1.00 21.21 ? 326 PRO A CD 1 ATOM 2672 N N . TYR A 1 327 ? -18.309 -19.029 -12.562 1.00 19.62 ? 327 TYR A N 1 ATOM 2673 C CA . TYR A 1 327 ? -18.217 -17.595 -12.333 1.00 19.74 ? 327 TYR A CA 1 ATOM 2674 C C . TYR A 1 327 ? -16.754 -17.166 -12.278 1.00 19.39 ? 327 TYR A C 1 ATOM 2675 O O . TYR A 1 327 ? -15.903 -17.920 -11.809 1.00 18.50 ? 327 TYR A O 1 ATOM 2676 C CB . TYR A 1 327 ? -18.895 -17.214 -11.010 1.00 19.53 ? 327 TYR A CB 1 ATOM 2677 C CG . TYR A 1 327 ? -20.418 -17.360 -11.029 1.00 21.13 ? 327 TYR A CG 1 ATOM 2678 C CD1 . TYR A 1 327 ? -21.159 -16.837 -12.075 1.00 20.58 ? 327 TYR A CD1 1 ATOM 2679 C CD2 . TYR A 1 327 ? -21.108 -17.961 -9.958 1.00 21.84 ? 327 TYR A CD2 1 ATOM 2680 C CE1 . TYR A 1 327 ? -22.530 -16.936 -12.107 1.00 23.20 ? 327 TYR A CE1 1 ATOM 2681 C CE2 . TYR A 1 327 ? -22.514 -18.061 -9.970 1.00 23.44 ? 327 TYR A CE2 1 ATOM 2682 C CZ . TYR A 1 327 ? -23.212 -17.533 -11.050 1.00 23.86 ? 327 TYR A CZ 1 ATOM 2683 O OH . TYR A 1 327 ? -24.580 -17.599 -11.121 1.00 24.89 ? 327 TYR A OH 1 ATOM 2684 N N . PHE A 1 328 ? -16.491 -15.945 -12.757 1.00 19.13 ? 328 PHE A N 1 ATOM 2685 C CA . PHE A 1 328 ? -15.152 -15.343 -12.726 1.00 18.51 ? 328 PHE A CA 1 ATOM 2686 C C . PHE A 1 328 ? -15.261 -13.928 -12.173 1.00 17.86 ? 328 PHE A C 1 ATOM 2687 O O . PHE A 1 328 ? -14.924 -12.977 -12.842 1.00 17.86 ? 328 PHE A O 1 ATOM 2688 C CB . PHE A 1 328 ? -14.571 -15.365 -14.152 1.00 18.57 ? 328 PHE A CB 1 ATOM 2689 C CG . PHE A 1 328 ? -14.491 -16.773 -14.724 1.00 20.49 ? 328 PHE A CG 1 ATOM 2690 C CD1 . PHE A 1 328 ? -13.328 -17.534 -14.576 1.00 18.88 ? 328 PHE A CD1 1 ATOM 2691 C CD2 . PHE A 1 328 ? -15.598 -17.345 -15.355 1.00 20.42 ? 328 PHE A CD2 1 ATOM 2692 C CE1 . PHE A 1 328 ? -13.263 -18.844 -15.075 1.00 21.48 ? 328 PHE A CE1 1 ATOM 2693 C CE2 . PHE A 1 328 ? -15.554 -18.655 -15.858 1.00 21.14 ? 328 PHE A CE2 1 ATOM 2694 C CZ . PHE A 1 328 ? -14.391 -19.412 -15.705 1.00 20.20 ? 328 PHE A CZ 1 ATOM 2695 N N . PHE A 1 329 ? -15.758 -13.787 -10.952 1.00 17.75 ? 329 PHE A N 1 ATOM 2696 C CA . PHE A 1 329 ? -16.108 -12.453 -10.461 1.00 16.97 ? 329 PHE A CA 1 ATOM 2697 C C . PHE A 1 329 ? -14.937 -11.523 -10.219 1.00 17.32 ? 329 PHE A C 1 ATOM 2698 O O . PHE A 1 329 ? -14.012 -11.875 -9.461 1.00 16.80 ? 329 PHE A O 1 ATOM 2699 C CB . PHE A 1 329 ? -16.897 -12.538 -9.166 1.00 16.82 ? 329 PHE A CB 1 ATOM 2700 C CG . PHE A 1 329 ? -18.250 -13.199 -9.309 1.00 17.16 ? 329 PHE A CG 1 ATOM 2701 C CD1 . PHE A 1 329 ? -19.211 -12.679 -10.168 1.00 15.68 ? 329 PHE A CD1 1 ATOM 2702 C CD2 . PHE A 1 329 ? -18.558 -14.334 -8.548 1.00 16.60 ? 329 PHE A CD2 1 ATOM 2703 C CE1 . PHE A 1 329 ? -20.478 -13.287 -10.279 1.00 17.01 ? 329 PHE A CE1 1 ATOM 2704 C CE2 . PHE A 1 329 ? -19.822 -14.941 -8.630 1.00 16.55 ? 329 PHE A CE2 1 ATOM 2705 C CZ . PHE A 1 329 ? -20.777 -14.412 -9.506 1.00 18.41 ? 329 PHE A CZ 1 ATOM 2706 N N . HIS A 1 330 ? -15.022 -10.338 -10.845 1.00 16.96 ? 330 HIS A N 1 ATOM 2707 C CA . HIS A 1 330 ? -14.378 -9.115 -10.363 1.00 17.97 ? 330 HIS A CA 1 ATOM 2708 C C . HIS A 1 330 ? -14.797 -8.939 -8.910 1.00 17.96 ? 330 HIS A C 1 ATOM 2709 O O . HIS A 1 330 ? -16.000 -8.960 -8.613 1.00 18.33 ? 330 HIS A O 1 ATOM 2710 C CB . HIS A 1 330 ? -14.888 -7.893 -11.136 1.00 16.87 ? 330 HIS A CB 1 ATOM 2711 C CG . HIS A 1 330 ? -14.222 -7.660 -12.459 1.00 19.33 ? 330 HIS A CG 1 ATOM 2712 N ND1 . HIS A 1 330 ? -14.386 -8.500 -13.544 1.00 19.71 ? 330 HIS A ND1 1 ATOM 2713 C CD2 . HIS A 1 330 ? -13.438 -6.635 -12.891 1.00 19.59 ? 330 HIS A CD2 1 ATOM 2714 C CE1 . HIS A 1 330 ? -13.700 -8.024 -14.570 1.00 20.65 ? 330 HIS A CE1 1 ATOM 2715 N NE2 . HIS A 1 330 ? -13.111 -6.899 -14.195 1.00 18.45 ? 330 HIS A NE2 1 ATOM 2716 N N . ALA A 1 331 ? -13.819 -8.778 -8.012 1.00 16.98 ? 331 ALA A N 1 ATOM 2717 C CA . ALA A 1 331 ? -14.099 -8.627 -6.575 1.00 16.20 ? 331 ALA A CA 1 ATOM 2718 C C . ALA A 1 331 ? -12.967 -7.970 -5.808 1.00 15.84 ? 331 ALA A C 1 ATOM 2719 O O . ALA A 1 331 ? -11.790 -8.336 -5.949 1.00 14.29 ? 331 ALA A O 1 ATOM 2720 C CB . ALA A 1 331 ? -14.445 -9.957 -5.931 1.00 16.24 ? 331 ALA A CB 1 ATOM 2721 N N . GLY A 1 332 ? -13.347 -6.996 -4.983 1.00 15.54 ? 332 GLY A N 1 ATOM 2722 C CA . GLY A 1 332 ? -12.406 -6.330 -4.085 1.00 15.59 ? 332 GLY A CA 1 ATOM 2723 C C . GLY A 1 332 ? -11.501 -5.347 -4.793 1.00 15.77 ? 332 GLY A C 1 ATOM 2724 O O . GLY A 1 332 ? -10.421 -5.046 -4.306 1.00 15.92 ? 332 GLY A O 1 ATOM 2725 N N . GLU A 1 333 ? -11.959 -4.818 -5.924 1.00 16.31 ? 333 GLU A N 1 ATOM 2726 C CA . GLU A 1 333 ? -11.216 -3.819 -6.679 1.00 16.78 ? 333 GLU A CA 1 ATOM 2727 C C . GLU A 1 333 ? -11.482 -2.438 -6.069 1.00 16.70 ? 333 GLU A C 1 ATOM 2728 O O . GLU A 1 333 ? -12.252 -1.635 -6.603 1.00 16.98 ? 333 GLU A O 1 ATOM 2729 C CB . GLU A 1 333 ? -11.585 -3.886 -8.164 1.00 16.89 ? 333 GLU A CB 1 ATOM 2730 C CG . GLU A 1 333 ? -10.620 -3.116 -9.090 1.00 18.02 ? 333 GLU A CG 1 ATOM 2731 C CD . GLU A 1 333 ? -11.173 -2.870 -10.483 1.00 21.86 ? 333 GLU A CD 1 ATOM 2732 O OE1 . GLU A 1 333 ? -12.234 -3.453 -10.846 1.00 22.37 ? 333 GLU A OE1 1 ATOM 2733 O OE2 . GLU A 1 333 ? -10.534 -2.097 -11.250 1.00 23.57 ? 333 GLU A OE2 1 ATOM 2734 N N . THR A 1 334 ? -10.876 -2.198 -4.909 1.00 16.00 ? 334 THR A N 1 ATOM 2735 C CA . THR A 1 334 ? -11.251 -1.063 -4.095 1.00 15.30 ? 334 THR A CA 1 ATOM 2736 C C . THR A 1 334 ? -10.223 -0.775 -3.014 1.00 15.88 ? 334 THR A C 1 ATOM 2737 O O . THR A 1 334 ? -9.548 -1.702 -2.487 1.00 14.71 ? 334 THR A O 1 ATOM 2738 C CB . THR A 1 334 ? -12.651 -1.318 -3.374 1.00 15.52 ? 334 THR A CB 1 ATOM 2739 O OG1 . THR A 1 334 ? -13.066 -0.146 -2.668 1.00 15.40 ? 334 THR A OG1 1 ATOM 2740 C CG2 . THR A 1 334 ? -12.589 -2.515 -2.389 1.00 14.42 ? 334 THR A CG2 1 ATOM 2741 N N . ASP A 1 335 ? -10.175 0.509 -2.649 1.00 14.64 ? 335 ASP A N 1 ATOM 2742 C CA . ASP A 1 335 ? -9.386 0.996 -1.520 1.00 16.00 ? 335 ASP A CA 1 ATOM 2743 C C . ASP A 1 335 ? -10.074 0.880 -0.171 1.00 15.42 ? 335 ASP A C 1 ATOM 2744 O O . ASP A 1 335 ? -9.425 1.019 0.878 1.00 15.26 ? 335 ASP A O 1 ATOM 2745 C CB . ASP A 1 335 ? -8.965 2.458 -1.777 1.00 15.48 ? 335 ASP A CB 1 ATOM 2746 C CG . ASP A 1 335 ? -7.935 2.567 -2.882 1.00 16.46 ? 335 ASP A CG 1 ATOM 2747 O OD1 . ASP A 1 335 ? -7.029 1.695 -2.916 1.00 15.11 ? 335 ASP A OD1 1 ATOM 2748 O OD2 . ASP A 1 335 ? -8.006 3.515 -3.705 1.00 12.10 ? 335 ASP A OD2 1 ATOM 2749 N N . TRP A 1 336 ? -11.375 0.607 -0.179 1.00 15.30 ? 336 TRP A N 1 ATOM 2750 C CA . TRP A 1 336 ? -12.129 0.560 1.081 1.00 16.16 ? 336 TRP A CA 1 ATOM 2751 C C . TRP A 1 336 ? -11.889 -0.799 1.757 1.00 17.22 ? 336 TRP A C 1 ATOM 2752 O O . TRP A 1 336 ? -11.557 -1.799 1.084 1.00 17.03 ? 336 TRP A O 1 ATOM 2753 C CB . TRP A 1 336 ? -13.634 0.796 0.855 1.00 15.63 ? 336 TRP A CB 1 ATOM 2754 C CG . TRP A 1 336 ? -13.946 2.165 0.221 1.00 16.49 ? 336 TRP A CG 1 ATOM 2755 C CD1 . TRP A 1 336 ? -14.397 2.399 -1.055 1.00 17.46 ? 336 TRP A CD1 1 ATOM 2756 C CD2 . TRP A 1 336 ? -13.804 3.453 0.833 1.00 17.30 ? 336 TRP A CD2 1 ATOM 2757 N NE1 . TRP A 1 336 ? -14.531 3.755 -1.275 1.00 18.91 ? 336 TRP A NE1 1 ATOM 2758 C CE2 . TRP A 1 336 ? -14.182 4.426 -0.134 1.00 19.15 ? 336 TRP A CE2 1 ATOM 2759 C CE3 . TRP A 1 336 ? -13.369 3.886 2.091 1.00 20.21 ? 336 TRP A CE3 1 ATOM 2760 C CZ2 . TRP A 1 336 ? -14.169 5.797 0.135 1.00 21.03 ? 336 TRP A CZ2 1 ATOM 2761 C CZ3 . TRP A 1 336 ? -13.346 5.251 2.359 1.00 21.49 ? 336 TRP A CZ3 1 ATOM 2762 C CH2 . TRP A 1 336 ? -13.747 6.192 1.385 1.00 21.65 ? 336 TRP A CH2 1 ATOM 2763 N N . GLN A 1 337 ? -12.027 -0.804 3.078 1.00 15.97 ? 337 GLN A N 1 ATOM 2764 C CA . GLN A 1 337 ? -11.771 -1.983 3.899 1.00 17.16 ? 337 GLN A CA 1 ATOM 2765 C C . GLN A 1 337 ? -12.895 -2.079 4.913 1.00 17.57 ? 337 GLN A C 1 ATOM 2766 O O . GLN A 1 337 ? -13.250 -1.074 5.546 1.00 17.12 ? 337 GLN A O 1 ATOM 2767 C CB . GLN A 1 337 ? -10.435 -1.863 4.672 1.00 15.25 ? 337 GLN A CB 1 ATOM 2768 C CG . GLN A 1 337 ? -10.191 -3.044 5.620 1.00 18.69 ? 337 GLN A CG 1 ATOM 2769 C CD . GLN A 1 337 ? -8.964 -2.895 6.512 1.00 19.33 ? 337 GLN A CD 1 ATOM 2770 O OE1 . GLN A 1 337 ? -8.608 -3.823 7.243 1.00 20.84 ? 337 GLN A OE1 1 ATOM 2771 N NE2 . GLN A 1 337 ? -8.290 -1.740 6.431 1.00 17.69 ? 337 GLN A NE2 1 ATOM 2772 N N . GLY A 1 338 ? -13.402 -3.292 5.108 1.00 18.23 ? 338 GLY A N 1 ATOM 2773 C CA . GLY A 1 338 ? -14.444 -3.526 6.101 1.00 18.58 ? 338 GLY A CA 1 ATOM 2774 C C . GLY A 1 338 ? -15.825 -3.106 5.633 1.00 18.53 ? 338 GLY A C 1 ATOM 2775 O O . GLY A 1 338 ? -16.734 -2.964 6.451 1.00 19.31 ? 338 GLY A O 1 ATOM 2776 N N . THR A 1 339 ? -15.998 -2.951 4.325 1.00 19.16 ? 339 THR A N 1 ATOM 2777 C CA . THR A 1 339 ? -17.250 -2.457 3.748 1.00 20.18 ? 339 THR A CA 1 ATOM 2778 C C . THR A 1 339 ? -17.952 -3.516 2.936 1.00 20.83 ? 339 THR A C 1 ATOM 2779 O O . THR A 1 339 ? -17.432 -4.632 2.751 1.00 20.20 ? 339 THR A O 1 ATOM 2780 C CB . THR A 1 339 ? -17.044 -1.197 2.848 1.00 20.24 ? 339 THR A CB 1 ATOM 2781 O OG1 . THR A 1 339 ? -16.371 -1.545 1.622 1.00 21.20 ? 339 THR A OG1 1 ATOM 2782 C CG2 . THR A 1 339 ? -16.236 -0.151 3.582 1.00 19.89 ? 339 THR A CG2 1 ATOM 2783 N N . SER A 1 340 ? -19.121 -3.157 2.406 1.00 20.12 ? 340 SER A N 1 ATOM 2784 C CA . SER A 1 340 ? -19.848 -4.092 1.538 1.00 20.60 ? 340 SER A CA 1 ATOM 2785 C C . SER A 1 340 ? -19.086 -4.351 0.230 1.00 19.61 ? 340 SER A C 1 ATOM 2786 O O . SER A 1 340 ? -19.302 -5.361 -0.436 1.00 19.59 ? 340 SER A O 1 ATOM 2787 C CB . SER A 1 340 ? -21.257 -3.551 1.236 1.00 20.90 ? 340 SER A CB 1 ATOM 2788 O OG . SER A 1 340 ? -21.118 -2.404 0.415 1.00 22.53 ? 340 SER A OG 1 ATOM 2789 N N . ILE A 1 341 ? -18.200 -3.442 -0.150 1.00 19.63 ? 341 ILE A N 1 ATOM 2790 C CA . ILE A 1 341 ? -17.473 -3.614 -1.417 1.00 19.45 ? 341 ILE A CA 1 ATOM 2791 C C . ILE A 1 341 ? -16.364 -4.672 -1.337 1.00 19.30 ? 341 ILE A C 1 ATOM 2792 O O . ILE A 1 341 ? -16.295 -5.546 -2.207 1.00 19.50 ? 341 ILE A O 1 ATOM 2793 C CB . ILE A 1 341 ? -16.919 -2.283 -1.974 1.00 18.90 ? 341 ILE A CB 1 ATOM 2794 C CG1 . ILE A 1 341 ? -18.033 -1.223 -2.023 1.00 21.41 ? 341 ILE A CG1 1 ATOM 2795 C CG2 . ILE A 1 341 ? -16.305 -2.494 -3.363 1.00 17.38 ? 341 ILE A CG2 1 ATOM 2796 C CD1 . ILE A 1 341 ? -17.531 0.197 -1.758 1.00 21.14 ? 341 ILE A CD1 1 ATOM 2797 N N . ASP A 1 342 ? -15.489 -4.589 -0.334 1.00 19.68 ? 342 ASP A N 1 ATOM 2798 C CA . ASP A 1 342 ? -14.448 -5.633 -0.190 1.00 19.95 ? 342 ASP A CA 1 ATOM 2799 C C . ASP A 1 342 ? -14.963 -7.003 0.284 1.00 20.23 ? 342 ASP A C 1 ATOM 2800 O O . ASP A 1 342 ? -14.303 -8.038 0.054 1.00 19.21 ? 342 ASP A O 1 ATOM 2801 C CB . ASP A 1 342 ? -13.235 -5.165 0.617 1.00 19.82 ? 342 ASP A CB 1 ATOM 2802 C CG . ASP A 1 342 ? -13.608 -4.539 1.964 1.00 21.41 ? 342 ASP A CG 1 ATOM 2803 O OD1 . ASP A 1 342 ? -14.422 -3.591 2.007 1.00 19.24 ? 342 ASP A OD1 1 ATOM 2804 O OD2 . ASP A 1 342 ? -13.057 -4.987 2.983 1.00 21.61 ? 342 ASP A OD2 1 ATOM 2805 N N . ARG A 1 343 ? -16.146 -7.027 0.908 1.00 20.20 ? 343 ARG A N 1 ATOM 2806 C CA . ARG A 1 343 ? -16.811 -8.304 1.159 1.00 20.36 ? 343 ARG A CA 1 ATOM 2807 C C . ARG A 1 343 ? -17.191 -9.060 -0.122 1.00 19.24 ? 343 ARG A C 1 ATOM 2808 O O . ARG A 1 343 ? -17.402 -10.262 -0.075 1.00 20.11 ? 343 ARG A O 1 ATOM 2809 C CB . ARG A 1 343 ? -18.008 -8.166 2.134 1.00 20.58 ? 343 ARG A CB 1 ATOM 2810 C CG . ARG A 1 343 ? -17.587 -8.492 3.566 1.00 25.63 ? 343 ARG A CG 1 ATOM 2811 C CD . ARG A 1 343 ? -18.707 -8.362 4.637 1.00 29.55 ? 343 ARG A CD 1 ATOM 2812 N NE . ARG A 1 343 ? -19.550 -7.174 4.478 1.00 30.27 ? 343 ARG A NE 1 ATOM 2813 C CZ . ARG A 1 343 ? -19.348 -5.997 5.069 1.00 31.06 ? 343 ARG A CZ 1 ATOM 2814 N NH1 . ARG A 1 343 ? -18.307 -5.798 5.872 1.00 30.56 ? 343 ARG A NH1 1 ATOM 2815 N NH2 . ARG A 1 343 ? -20.194 -5.000 4.848 1.00 30.02 ? 343 ARG A NH2 1 ATOM 2816 N N . ASN A 1 344 ? -17.243 -8.390 -1.269 1.00 18.77 ? 344 ASN A N 1 ATOM 2817 C CA . ASN A 1 344 ? -17.457 -9.120 -2.536 1.00 17.81 ? 344 ASN A CA 1 ATOM 2818 C C . ASN A 1 344 ? -16.478 -10.280 -2.749 1.00 17.84 ? 344 ASN A C 1 ATOM 2819 O O . ASN A 1 344 ? -16.810 -11.251 -3.427 1.00 17.12 ? 344 ASN A O 1 ATOM 2820 C CB . ASN A 1 344 ? -17.458 -8.183 -3.762 1.00 17.38 ? 344 ASN A CB 1 ATOM 2821 C CG . ASN A 1 344 ? -18.740 -7.330 -3.875 1.00 18.39 ? 344 ASN A CG 1 ATOM 2822 O OD1 . ASN A 1 344 ? -19.856 -7.796 -3.561 1.00 18.37 ? 344 ASN A OD1 1 ATOM 2823 N ND2 . ASN A 1 344 ? -18.586 -6.090 -4.344 1.00 18.03 ? 344 ASN A ND2 1 ATOM 2824 N N . ILE A 1 345 ? -15.271 -10.200 -2.179 1.00 16.72 ? 345 ILE A N 1 ATOM 2825 C CA . ILE A 1 345 ? -14.332 -11.315 -2.336 1.00 17.68 ? 345 ILE A CA 1 ATOM 2826 C C . ILE A 1 345 ? -14.837 -12.588 -1.609 1.00 17.96 ? 345 ILE A C 1 ATOM 2827 O O . ILE A 1 345 ? -14.825 -13.677 -2.159 1.00 17.95 ? 345 ILE A O 1 ATOM 2828 C CB . ILE A 1 345 ? -12.892 -10.982 -1.827 1.00 17.59 ? 345 ILE A CB 1 ATOM 2829 C CG1 . ILE A 1 345 ? -12.339 -9.708 -2.517 1.00 16.96 ? 345 ILE A CG1 1 ATOM 2830 C CG2 . ILE A 1 345 ? -11.982 -12.208 -2.044 1.00 17.81 ? 345 ILE A CG2 1 ATOM 2831 C CD1 . ILE A 1 345 ? -10.977 -9.188 -1.952 1.00 15.56 ? 345 ILE A CD1 1 ATOM 2832 N N . LEU A 1 346 ? -15.244 -12.428 -0.364 1.00 18.60 ? 346 LEU A N 1 ATOM 2833 C CA . LEU A 1 346 ? -15.830 -13.515 0.395 1.00 19.18 ? 346 LEU A CA 1 ATOM 2834 C C . LEU A 1 346 ? -17.022 -14.124 -0.360 1.00 19.39 ? 346 LEU A C 1 ATOM 2835 O O . LEU A 1 346 ? -17.086 -15.333 -0.548 1.00 19.64 ? 346 LEU A O 1 ATOM 2836 C CB . LEU A 1 346 ? -16.259 -12.980 1.771 1.00 19.56 ? 346 LEU A CB 1 ATOM 2837 C CG . LEU A 1 346 ? -17.133 -13.861 2.673 1.00 19.49 ? 346 LEU A CG 1 ATOM 2838 C CD1 . LEU A 1 346 ? -16.412 -15.126 3.070 1.00 19.65 ? 346 LEU A CD1 1 ATOM 2839 C CD2 . LEU A 1 346 ? -17.428 -13.038 3.905 1.00 21.94 ? 346 LEU A CD2 1 ATOM 2840 N N . ASP A 1 347 ? -17.929 -13.267 -0.818 1.00 19.61 ? 347 ASP A N 1 ATOM 2841 C CA . ASP A 1 347 ? -19.147 -13.678 -1.540 1.00 21.06 ? 347 ASP A CA 1 ATOM 2842 C C . ASP A 1 347 ? -18.889 -14.378 -2.892 1.00 21.03 ? 347 ASP A C 1 ATOM 2843 O O . ASP A 1 347 ? -19.581 -15.331 -3.248 1.00 20.61 ? 347 ASP A O 1 ATOM 2844 C CB . ASP A 1 347 ? -20.089 -12.480 -1.695 1.00 21.24 ? 347 ASP A CB 1 ATOM 2845 C CG . ASP A 1 347 ? -20.863 -12.193 -0.415 1.00 24.02 ? 347 ASP A CG 1 ATOM 2846 O OD1 . ASP A 1 347 ? -21.060 -13.138 0.385 1.00 26.17 ? 347 ASP A OD1 1 ATOM 2847 O OD2 . ASP A 1 347 ? -21.270 -11.035 -0.201 1.00 24.73 ? 347 ASP A OD2 1 ATOM 2848 N N . ALA A 1 348 ? -17.871 -13.917 -3.616 1.00 21.16 ? 348 ALA A N 1 ATOM 2849 C CA . ALA A 1 348 ? -17.428 -14.586 -4.829 1.00 21.19 ? 348 ALA A CA 1 ATOM 2850 C C . ALA A 1 348 ? -16.977 -16.007 -4.492 1.00 21.04 ? 348 ALA A C 1 ATOM 2851 O O . ALA A 1 348 ? -17.316 -16.956 -5.192 1.00 21.13 ? 348 ALA A O 1 ATOM 2852 C CB . ALA A 1 348 ? -16.286 -13.782 -5.515 1.00 19.78 ? 348 ALA A CB 1 ATOM 2853 N N . LEU A 1 349 ? -16.221 -16.154 -3.414 1.00 22.28 ? 349 LEU A N 1 ATOM 2854 C CA . LEU A 1 349 ? -15.773 -17.483 -2.965 1.00 22.88 ? 349 LEU A CA 1 ATOM 2855 C C . LEU A 1 349 ? -16.927 -18.397 -2.493 1.00 23.34 ? 349 LEU A C 1 ATOM 2856 O O . LEU A 1 349 ? -16.906 -19.610 -2.736 1.00 22.21 ? 349 LEU A O 1 ATOM 2857 C CB . LEU A 1 349 ? -14.763 -17.338 -1.840 1.00 23.17 ? 349 LEU A CB 1 ATOM 2858 C CG . LEU A 1 349 ? -13.248 -17.516 -2.026 1.00 25.14 ? 349 LEU A CG 1 ATOM 2859 C CD1 . LEU A 1 349 ? -12.758 -17.673 -3.454 1.00 23.69 ? 349 LEU A CD1 1 ATOM 2860 C CD2 . LEU A 1 349 ? -12.515 -16.418 -1.252 1.00 22.45 ? 349 LEU A CD2 1 ATOM 2861 N N . MET A 1 350 ? -17.908 -17.814 -1.804 1.00 23.87 ? 350 MET A N 1 ATOM 2862 C CA . MET A 1 350 ? -19.109 -18.559 -1.385 1.00 23.93 ? 350 MET A CA 1 ATOM 2863 C C . MET A 1 350 ? -19.944 -19.014 -2.590 1.00 24.75 ? 350 MET A C 1 ATOM 2864 O O . MET A 1 350 ? -20.669 -20.013 -2.535 1.00 25.11 ? 350 MET A O 1 ATOM 2865 C CB . MET A 1 350 ? -19.952 -17.722 -0.434 1.00 23.80 ? 350 MET A CB 1 ATOM 2866 C CG . MET A 1 350 ? -19.308 -17.387 0.923 1.00 23.50 ? 350 MET A CG 1 ATOM 2867 S SD . MET A 1 350 ? -18.670 -18.773 1.870 1.00 25.64 ? 350 MET A SD 1 ATOM 2868 C CE . MET A 1 350 ? -16.973 -19.001 1.329 1.00 24.42 ? 350 MET A CE 1 ATOM 2869 N N . LEU A 1 351 ? -19.849 -18.265 -3.681 1.00 24.53 ? 351 LEU A N 1 ATOM 2870 C CA . LEU A 1 351 ? -20.514 -18.634 -4.931 1.00 24.24 ? 351 LEU A CA 1 ATOM 2871 C C . LEU A 1 351 ? -19.623 -19.498 -5.849 1.00 24.14 ? 351 LEU A C 1 ATOM 2872 O O . LEU A 1 351 ? -19.898 -19.638 -7.047 1.00 23.11 ? 351 LEU A O 1 ATOM 2873 C CB . LEU A 1 351 ? -20.984 -17.377 -5.647 1.00 24.18 ? 351 LEU A CB 1 ATOM 2874 C CG . LEU A 1 351 ? -22.098 -16.574 -4.974 1.00 24.75 ? 351 LEU A CG 1 ATOM 2875 C CD1 . LEU A 1 351 ? -22.168 -15.183 -5.587 1.00 24.73 ? 351 LEU A CD1 1 ATOM 2876 C CD2 . LEU A 1 351 ? -23.442 -17.324 -5.146 1.00 25.73 ? 351 LEU A CD2 1 ATOM 2877 N N . ASN A 1 352 ? -18.563 -20.068 -5.268 1.00 24.16 ? 352 ASN A N 1 ATOM 2878 C CA . ASN A 1 352 ? -17.619 -20.973 -5.958 1.00 24.66 ? 352 ASN A CA 1 ATOM 2879 C C . ASN A 1 352 ? -16.954 -20.400 -7.189 1.00 23.48 ? 352 ASN A C 1 ATOM 2880 O O . ASN A 1 352 ? -16.750 -21.115 -8.168 1.00 23.00 ? 352 ASN A O 1 ATOM 2881 C CB . ASN A 1 352 ? -18.275 -22.309 -6.346 1.00 25.88 ? 352 ASN A CB 1 ATOM 2882 C CG . ASN A 1 352 ? -19.106 -22.891 -5.234 1.00 30.51 ? 352 ASN A CG 1 ATOM 2883 O OD1 . ASN A 1 352 ? -18.799 -22.701 -4.053 1.00 33.42 ? 352 ASN A OD1 1 ATOM 2884 N ND2 . ASN A 1 352 ? -20.179 -23.609 -5.610 1.00 37.30 ? 352 ASN A ND2 1 ATOM 2885 N N . THR A 1 353 ? -16.604 -19.115 -7.148 1.00 22.24 ? 353 THR A N 1 ATOM 2886 C CA . THR A 1 353 ? -15.888 -18.517 -8.265 1.00 20.96 ? 353 THR A CA 1 ATOM 2887 C C . THR A 1 353 ? -14.636 -19.349 -8.636 1.00 20.98 ? 353 THR A C 1 ATOM 2888 O O . THR A 1 353 ? -13.984 -19.915 -7.764 1.00 21.27 ? 353 THR A O 1 ATOM 2889 C CB . THR A 1 353 ? -15.542 -17.041 -7.959 1.00 21.13 ? 353 THR A CB 1 ATOM 2890 O OG1 . THR A 1 353 ? -15.205 -16.359 -9.173 1.00 20.18 ? 353 THR A OG1 1 ATOM 2891 C CG2 . THR A 1 353 ? -14.409 -16.934 -6.932 1.00 19.61 ? 353 THR A CG2 1 ATOM 2892 N N . THR A 1 354 ? -14.335 -19.442 -9.935 1.00 20.87 ? 354 THR A N 1 ATOM 2893 C CA . THR A 1 354 ? -13.171 -20.186 -10.437 1.00 20.52 ? 354 THR A CA 1 ATOM 2894 C C . THR A 1 354 ? -11.906 -19.348 -10.294 1.00 20.09 ? 354 THR A C 1 ATOM 2895 O O . THR A 1 354 ? -10.850 -19.885 -9.947 1.00 19.49 ? 354 THR A O 1 ATOM 2896 C CB . THR A 1 354 ? -13.348 -20.573 -11.933 1.00 20.74 ? 354 THR A CB 1 ATOM 2897 O OG1 . THR A 1 354 ? -14.563 -21.308 -12.077 1.00 22.35 ? 354 THR A OG1 1 ATOM 2898 C CG2 . THR A 1 354 ? -12.172 -21.421 -12.456 1.00 19.37 ? 354 THR A CG2 1 ATOM 2899 N N . ARG A 1 355 ? -12.018 -18.053 -10.616 1.00 19.67 ? 355 ARG A N 1 ATOM 2900 C CA . ARG A 1 355 ? -10.951 -17.067 -10.362 1.00 19.25 ? 355 ARG A CA 1 ATOM 2901 C C . ARG A 1 355 ? -11.568 -15.782 -9.786 1.00 19.64 ? 355 ARG A C 1 ATOM 2902 O O . ARG A 1 355 ? -12.781 -15.539 -9.922 1.00 19.95 ? 355 ARG A O 1 ATOM 2903 C CB . ARG A 1 355 ? -10.131 -16.763 -11.644 1.00 18.90 ? 355 ARG A CB 1 ATOM 2904 C CG . ARG A 1 355 ? -9.451 -17.991 -12.299 1.00 18.31 ? 355 ARG A CG 1 ATOM 2905 C CD . ARG A 1 355 ? -8.483 -17.636 -13.459 1.00 16.97 ? 355 ARG A CD 1 ATOM 2906 N NE . ARG A 1 355 ? -9.091 -16.775 -14.480 1.00 16.61 ? 355 ARG A NE 1 ATOM 2907 C CZ . ARG A 1 355 ? -9.630 -17.189 -15.629 1.00 18.47 ? 355 ARG A CZ 1 ATOM 2908 N NH1 . ARG A 1 355 ? -9.605 -18.471 -15.940 1.00 19.92 ? 355 ARG A NH1 1 ATOM 2909 N NH2 . ARG A 1 355 ? -10.162 -16.311 -16.503 1.00 16.41 ? 355 ARG A NH2 1 ATOM 2910 N N . ILE A 1 356 ? -10.730 -14.967 -9.150 1.00 18.67 ? 356 ILE A N 1 ATOM 2911 C CA . ILE A 1 356 ? -11.147 -13.694 -8.605 1.00 17.49 ? 356 ILE A CA 1 ATOM 2912 C C . ILE A 1 356 ? -10.429 -12.626 -9.407 1.00 17.15 ? 356 ILE A C 1 ATOM 2913 O O . ILE A 1 356 ? -9.186 -12.633 -9.485 1.00 17.72 ? 356 ILE A O 1 ATOM 2914 C CB . ILE A 1 356 ? -10.726 -13.555 -7.140 1.00 18.09 ? 356 ILE A CB 1 ATOM 2915 C CG1 . ILE A 1 356 ? -11.349 -14.660 -6.267 1.00 17.02 ? 356 ILE A CG1 1 ATOM 2916 C CG2 . ILE A 1 356 ? -11.006 -12.146 -6.625 1.00 17.73 ? 356 ILE A CG2 1 ATOM 2917 C CD1 . ILE A 1 356 ? -10.560 -14.956 -4.987 1.00 19.06 ? 356 ILE A CD1 1 ATOM 2918 N N . GLY A 1 357 ? -11.209 -11.731 -10.007 1.00 16.05 ? 357 GLY A N 1 ATOM 2919 C CA . GLY A 1 357 ? -10.680 -10.590 -10.773 1.00 15.89 ? 357 GLY A CA 1 ATOM 2920 C C . GLY A 1 357 ? -10.220 -9.496 -9.826 1.00 15.96 ? 357 GLY A C 1 ATOM 2921 O O . GLY A 1 357 ? -11.020 -9.009 -9.010 1.00 15.45 ? 357 GLY A O 1 ATOM 2922 N N . HIS A 1 358 ? -8.929 -9.148 -9.915 1.00 14.71 ? 358 HIS A N 1 ATOM 2923 C CA . HIS A 1 358 ? -8.245 -8.194 -9.004 1.00 15.78 ? 358 HIS A CA 1 ATOM 2924 C C . HIS A 1 358 ? -7.966 -8.686 -7.581 1.00 16.11 ? 358 HIS A C 1 ATOM 2925 O O . HIS A 1 358 ? -6.816 -8.893 -7.230 1.00 16.59 ? 358 HIS A O 1 ATOM 2926 C CB . HIS A 1 358 ? -8.925 -6.790 -8.984 1.00 15.34 ? 358 HIS A CB 1 ATOM 2927 C CG . HIS A 1 358 ? -9.056 -6.172 -10.349 1.00 16.12 ? 358 HIS A CG 1 ATOM 2928 N ND1 . HIS A 1 358 ? -7.995 -5.583 -11.011 1.00 15.04 ? 358 HIS A ND1 1 ATOM 2929 C CD2 . HIS A 1 358 ? -10.124 -6.052 -11.170 1.00 16.41 ? 358 HIS A CD2 1 ATOM 2930 C CE1 . HIS A 1 358 ? -8.407 -5.129 -12.178 1.00 15.30 ? 358 HIS A CE1 1 ATOM 2931 N NE2 . HIS A 1 358 ? -9.701 -5.380 -12.289 1.00 16.40 ? 358 HIS A NE2 1 ATOM 2932 N N . GLY A 1 359 ? -9.011 -8.884 -6.779 1.00 15.59 ? 359 GLY A N 1 ATOM 2933 C CA . GLY A 1 359 ? -8.855 -9.217 -5.360 1.00 15.89 ? 359 GLY A CA 1 ATOM 2934 C C . GLY A 1 359 ? -7.875 -8.288 -4.640 1.00 15.55 ? 359 GLY A C 1 ATOM 2935 O O . GLY A 1 359 ? -7.153 -8.713 -3.768 1.00 14.51 ? 359 GLY A O 1 ATOM 2936 N N . PHE A 1 360 ? -7.871 -7.013 -5.033 1.00 15.26 ? 360 PHE A N 1 ATOM 2937 C CA . PHE A 1 360 ? -6.938 -6.009 -4.539 1.00 14.75 ? 360 PHE A CA 1 ATOM 2938 C C . PHE A 1 360 ? -7.044 -5.915 -3.022 1.00 15.10 ? 360 PHE A C 1 ATOM 2939 O O . PHE A 1 360 ? -6.033 -5.773 -2.341 1.00 15.71 ? 360 PHE A O 1 ATOM 2940 C CB . PHE A 1 360 ? -7.264 -4.670 -5.224 1.00 13.81 ? 360 PHE A CB 1 ATOM 2941 C CG . PHE A 1 360 ? -6.356 -3.528 -4.848 1.00 12.88 ? 360 PHE A CG 1 ATOM 2942 C CD1 . PHE A 1 360 ? -6.654 -2.723 -3.758 1.00 13.86 ? 360 PHE A CD1 1 ATOM 2943 C CD2 . PHE A 1 360 ? -5.247 -3.209 -5.640 1.00 12.03 ? 360 PHE A CD2 1 ATOM 2944 C CE1 . PHE A 1 360 ? -5.839 -1.639 -3.412 1.00 13.72 ? 360 PHE A CE1 1 ATOM 2945 C CE2 . PHE A 1 360 ? -4.403 -2.133 -5.300 1.00 8.20 ? 360 PHE A CE2 1 ATOM 2946 C CZ . PHE A 1 360 ? -4.703 -1.337 -4.173 1.00 10.83 ? 360 PHE A CZ 1 ATOM 2947 N N . ALA A 1 361 ? -8.263 -6.073 -2.499 1.00 14.54 ? 361 ALA A N 1 ATOM 2948 C CA . ALA A 1 361 ? -8.516 -5.989 -1.047 1.00 15.57 ? 361 ALA A CA 1 ATOM 2949 C C . ALA A 1 361 ? -8.194 -7.282 -0.270 1.00 16.19 ? 361 ALA A C 1 ATOM 2950 O O . ALA A 1 361 ? -8.313 -7.328 0.960 1.00 15.49 ? 361 ALA A O 1 ATOM 2951 C CB . ALA A 1 361 ? -9.979 -5.542 -0.784 1.00 14.07 ? 361 ALA A CB 1 ATOM 2952 N N . LEU A 1 362 ? -7.753 -8.317 -0.978 1.00 17.20 ? 362 LEU A N 1 ATOM 2953 C CA . LEU A 1 362 ? -7.563 -9.647 -0.336 1.00 18.58 ? 362 LEU A CA 1 ATOM 2954 C C . LEU A 1 362 ? -6.611 -9.719 0.857 1.00 18.78 ? 362 LEU A C 1 ATOM 2955 O O . LEU A 1 362 ? -6.892 -10.422 1.854 1.00 18.53 ? 362 LEU A O 1 ATOM 2956 C CB . LEU A 1 362 ? -7.126 -10.704 -1.357 1.00 18.16 ? 362 LEU A CB 1 ATOM 2957 C CG . LEU A 1 362 ? -7.628 -12.154 -1.265 1.00 20.93 ? 362 LEU A CG 1 ATOM 2958 C CD1 . LEU A 1 362 ? -6.556 -13.149 -1.744 1.00 20.63 ? 362 LEU A CD1 1 ATOM 2959 C CD2 . LEU A 1 362 ? -8.339 -12.615 0.034 1.00 17.83 ? 362 LEU A CD2 1 ATOM 2960 N N . SER A 1 363 ? -5.476 -9.029 0.773 1.00 18.96 ? 363 SER A N 1 ATOM 2961 C CA . SER A 1 363 ? -4.524 -9.110 1.899 1.00 19.80 ? 363 SER A CA 1 ATOM 2962 C C . SER A 1 363 ? -5.052 -8.502 3.204 1.00 19.53 ? 363 SER A C 1 ATOM 2963 O O . SER A 1 363 ? -4.492 -8.759 4.254 1.00 19.08 ? 363 SER A O 1 ATOM 2964 C CB . SER A 1 363 ? -3.182 -8.478 1.569 1.00 19.27 ? 363 SER A CB 1 ATOM 2965 O OG . SER A 1 363 ? -3.356 -7.092 1.327 1.00 20.16 ? 363 SER A OG 1 ATOM 2966 N N . LYS A 1 364 ? -6.116 -7.703 3.145 1.00 19.47 ? 364 LYS A N 1 ATOM 2967 C CA . LYS A 1 364 ? -6.696 -7.162 4.378 1.00 19.56 ? 364 LYS A CA 1 ATOM 2968 C C . LYS A 1 364 ? -7.642 -8.170 5.048 1.00 19.59 ? 364 LYS A C 1 ATOM 2969 O O . LYS A 1 364 ? -8.184 -7.893 6.120 1.00 20.27 ? 364 LYS A O 1 ATOM 2970 C CB . LYS A 1 364 ? -7.410 -5.827 4.113 1.00 20.58 ? 364 LYS A CB 1 ATOM 2971 C CG . LYS A 1 364 ? -6.431 -4.684 3.756 1.00 22.18 ? 364 LYS A CG 1 ATOM 2972 C CD . LYS A 1 364 ? -7.109 -3.371 3.461 1.00 25.63 ? 364 LYS A CD 1 ATOM 2973 C CE . LYS A 1 364 ? -6.210 -2.501 2.554 1.00 25.50 ? 364 LYS A CE 1 ATOM 2974 N NZ . LYS A 1 364 ? -6.171 -2.955 1.112 1.00 30.30 ? 364 LYS A NZ 1 ATOM 2975 N N . HIS A 1 365 ? -7.857 -9.316 4.406 1.00 18.88 ? 365 HIS A N 1 ATOM 2976 C CA . HIS A 1 365 ? -8.794 -10.347 4.913 1.00 19.65 ? 365 HIS A CA 1 ATOM 2977 C C . HIS A 1 365 ? -8.131 -11.694 5.103 1.00 19.20 ? 365 HIS A C 1 ATOM 2978 O O . HIS A 1 365 ? -8.233 -12.578 4.242 1.00 18.81 ? 365 HIS A O 1 ATOM 2979 C CB . HIS A 1 365 ? -10.018 -10.476 4.016 1.00 19.02 ? 365 HIS A CB 1 ATOM 2980 C CG . HIS A 1 365 ? -10.908 -9.292 4.082 1.00 20.12 ? 365 HIS A CG 1 ATOM 2981 N ND1 . HIS A 1 365 ? -10.820 -8.250 3.182 1.00 23.36 ? 365 HIS A ND1 1 ATOM 2982 C CD2 . HIS A 1 365 ? -11.859 -8.943 4.976 1.00 19.38 ? 365 HIS A CD2 1 ATOM 2983 C CE1 . HIS A 1 365 ? -11.708 -7.325 3.501 1.00 22.88 ? 365 HIS A CE1 1 ATOM 2984 N NE2 . HIS A 1 365 ? -12.357 -7.725 4.582 1.00 25.35 ? 365 HIS A NE2 1 ATOM 2985 N N . PRO A 1 366 ? -7.453 -11.864 6.239 1.00 19.67 ? 366 PRO A N 1 ATOM 2986 C CA . PRO A 1 366 ? -6.622 -13.071 6.315 1.00 20.03 ? 366 PRO A CA 1 ATOM 2987 C C . PRO A 1 366 ? -7.403 -14.396 6.338 1.00 20.26 ? 366 PRO A C 1 ATOM 2988 O O . PRO A 1 366 ? -6.865 -15.390 5.867 1.00 19.60 ? 366 PRO A O 1 ATOM 2989 C CB . PRO A 1 366 ? -5.791 -12.863 7.591 1.00 19.75 ? 366 PRO A CB 1 ATOM 2990 C CG . PRO A 1 366 ? -6.607 -11.908 8.425 1.00 21.10 ? 366 PRO A CG 1 ATOM 2991 C CD . PRO A 1 366 ? -7.331 -11.004 7.438 1.00 19.47 ? 366 PRO A CD 1 ATOM 2992 N N . ALA A 1 367 ? -8.637 -14.424 6.870 1.00 20.57 ? 367 ALA A N 1 ATOM 2993 C CA . ALA A 1 367 ? -9.449 -15.650 6.780 1.00 21.20 ? 367 ALA A CA 1 ATOM 2994 C C . ALA A 1 367 ? -9.857 -15.970 5.348 1.00 20.73 ? 367 ALA A C 1 ATOM 2995 O O . ALA A 1 367 ? -9.800 -17.124 4.931 1.00 20.30 ? 367 ALA A O 1 ATOM 2996 C CB . ALA A 1 367 ? -10.697 -15.614 7.699 1.00 20.93 ? 367 ALA A CB 1 ATOM 2997 N N . VAL A 1 368 ? -10.275 -14.950 4.598 1.00 20.80 ? 368 VAL A N 1 ATOM 2998 C CA . VAL A 1 368 ? -10.604 -15.126 3.175 1.00 20.84 ? 368 VAL A CA 1 ATOM 2999 C C . VAL A 1 368 ? -9.375 -15.558 2.340 1.00 21.27 ? 368 VAL A C 1 ATOM 3000 O O . VAL A 1 368 ? -9.475 -16.411 1.428 1.00 20.81 ? 368 VAL A O 1 ATOM 3001 C CB . VAL A 1 368 ? -11.249 -13.828 2.621 1.00 20.75 ? 368 VAL A CB 1 ATOM 3002 C CG1 . VAL A 1 368 ? -11.749 -14.010 1.203 1.00 21.64 ? 368 VAL A CG1 1 ATOM 3003 C CG2 . VAL A 1 368 ? -12.371 -13.409 3.512 1.00 20.61 ? 368 VAL A CG2 1 ATOM 3004 N N . ARG A 1 369 ? -8.231 -14.947 2.646 1.00 21.03 ? 369 ARG A N 1 ATOM 3005 C CA . ARG A 1 369 ? -6.954 -15.273 2.024 1.00 22.18 ? 369 ARG A CA 1 ATOM 3006 C C . ARG A 1 369 ? -6.624 -16.762 2.208 1.00 22.19 ? 369 ARG A C 1 ATOM 3007 O O . ARG A 1 369 ? -6.411 -17.467 1.227 1.00 20.95 ? 369 ARG A O 1 ATOM 3008 C CB . ARG A 1 369 ? -5.854 -14.361 2.589 1.00 22.08 ? 369 ARG A CB 1 ATOM 3009 C CG . ARG A 1 369 ? -4.419 -14.582 2.050 1.00 24.49 ? 369 ARG A CG 1 ATOM 3010 C CD . ARG A 1 369 ? -3.476 -13.627 2.789 1.00 28.39 ? 369 ARG A CD 1 ATOM 3011 N NE . ARG A 1 369 ? -2.069 -13.826 2.453 1.00 31.06 ? 369 ARG A NE 1 ATOM 3012 C CZ . ARG A 1 369 ? -1.080 -13.013 2.828 1.00 32.04 ? 369 ARG A CZ 1 ATOM 3013 N NH1 . ARG A 1 369 ? -1.328 -11.916 3.553 1.00 32.53 ? 369 ARG A NH1 1 ATOM 3014 N NH2 . ARG A 1 369 ? 0.168 -13.292 2.467 1.00 31.10 ? 369 ARG A NH2 1 ATOM 3015 N N . THR A 1 370 ? -6.640 -17.234 3.456 1.00 22.80 ? 370 THR A N 1 ATOM 3016 C CA . THR A 1 370 ? -6.480 -18.676 3.755 1.00 23.72 ? 370 THR A CA 1 ATOM 3017 C C . THR A 1 370 ? -7.456 -19.582 3.002 1.00 24.17 ? 370 THR A C 1 ATOM 3018 O O . THR A 1 370 ? -7.040 -20.584 2.430 1.00 24.60 ? 370 THR A O 1 ATOM 3019 C CB . THR A 1 370 ? -6.574 -18.947 5.275 1.00 23.51 ? 370 THR A CB 1 ATOM 3020 O OG1 . THR A 1 370 ? -5.554 -18.208 5.918 1.00 23.60 ? 370 THR A OG1 1 ATOM 3021 C CG2 . THR A 1 370 ? -6.371 -20.426 5.605 1.00 24.61 ? 370 THR A CG2 1 ATOM 3022 N N . TYR A 1 371 ? -8.734 -19.215 2.989 1.00 24.65 ? 371 TYR A N 1 ATOM 3023 C CA . TYR A 1 371 ? -9.782 -19.990 2.315 1.00 25.74 ? 371 TYR A CA 1 ATOM 3024 C C . TYR A 1 371 ? -9.467 -20.102 0.818 1.00 26.37 ? 371 TYR A C 1 ATOM 3025 O O . TYR A 1 371 ? -9.480 -21.204 0.242 1.00 26.79 ? 371 TYR A O 1 ATOM 3026 C CB . TYR A 1 371 ? -11.156 -19.337 2.553 1.00 26.11 ? 371 TYR A CB 1 ATOM 3027 C CG . TYR A 1 371 ? -12.347 -20.154 2.079 1.00 28.06 ? 371 TYR A CG 1 ATOM 3028 C CD1 . TYR A 1 371 ? -12.853 -19.989 0.795 1.00 29.75 ? 371 TYR A CD1 1 ATOM 3029 C CD2 . TYR A 1 371 ? -12.958 -21.096 2.915 1.00 31.15 ? 371 TYR A CD2 1 ATOM 3030 C CE1 . TYR A 1 371 ? -13.926 -20.732 0.345 1.00 31.73 ? 371 TYR A CE1 1 ATOM 3031 C CE2 . TYR A 1 371 ? -14.059 -21.849 2.472 1.00 33.79 ? 371 TYR A CE2 1 ATOM 3032 C CZ . TYR A 1 371 ? -14.527 -21.657 1.187 1.00 33.43 ? 371 TYR A CZ 1 ATOM 3033 O OH . TYR A 1 371 ? -15.594 -22.381 0.717 1.00 36.19 ? 371 TYR A OH 1 ATOM 3034 N N . SER A 1 372 ? -9.171 -18.957 0.203 1.00 25.91 ? 372 SER A N 1 ATOM 3035 C CA . SER A 1 372 ? -8.773 -18.876 -1.196 1.00 26.60 ? 372 SER A CA 1 ATOM 3036 C C . SER A 1 372 ? -7.524 -19.741 -1.501 1.00 26.90 ? 372 SER A C 1 ATOM 3037 O O . SER A 1 372 ? -7.463 -20.437 -2.515 1.00 26.45 ? 372 SER A O 1 ATOM 3038 C CB . SER A 1 372 ? -8.552 -17.398 -1.563 1.00 26.11 ? 372 SER A CB 1 ATOM 3039 O OG . SER A 1 372 ? -7.404 -17.236 -2.384 1.00 28.04 ? 372 SER A OG 1 ATOM 3040 N N . TRP A 1 373 ? -6.540 -19.685 -0.615 1.00 27.64 ? 373 TRP A N 1 ATOM 3041 C CA . TRP A 1 373 ? -5.319 -20.467 -0.746 1.00 29.54 ? 373 TRP A CA 1 ATOM 3042 C C . TRP A 1 373 ? -5.643 -21.975 -0.673 1.00 29.70 ? 373 TRP A C 1 ATOM 3043 O O . TRP A 1 373 ? -5.230 -22.751 -1.545 1.00 29.57 ? 373 TRP A O 1 ATOM 3044 C CB . TRP A 1 373 ? -4.323 -20.031 0.330 1.00 30.06 ? 373 TRP A CB 1 ATOM 3045 C CG . TRP A 1 373 ? -3.027 -20.754 0.299 1.00 34.52 ? 373 TRP A CG 1 ATOM 3046 C CD1 . TRP A 1 373 ? -1.919 -20.435 -0.440 1.00 36.42 ? 373 TRP A CD1 1 ATOM 3047 C CD2 . TRP A 1 373 ? -2.691 -21.932 1.041 1.00 38.41 ? 373 TRP A CD2 1 ATOM 3048 N NE1 . TRP A 1 373 ? -0.922 -21.342 -0.208 1.00 40.15 ? 373 TRP A NE1 1 ATOM 3049 C CE2 . TRP A 1 373 ? -1.365 -22.273 0.700 1.00 39.03 ? 373 TRP A CE2 1 ATOM 3050 C CE3 . TRP A 1 373 ? -3.381 -22.726 1.968 1.00 39.07 ? 373 TRP A CE3 1 ATOM 3051 C CZ2 . TRP A 1 373 ? -0.710 -23.374 1.251 1.00 42.12 ? 373 TRP A CZ2 1 ATOM 3052 C CZ3 . TRP A 1 373 ? -2.729 -23.827 2.519 1.00 43.50 ? 373 TRP A CZ3 1 ATOM 3053 C CH2 . TRP A 1 373 ? -1.406 -24.142 2.156 1.00 42.60 ? 373 TRP A CH2 1 ATOM 3054 N N . LYS A 1 374 ? -6.424 -22.367 0.333 1.00 30.08 ? 374 LYS A N 1 ATOM 3055 C CA . LYS A 1 374 ? -6.840 -23.762 0.497 1.00 31.12 ? 374 LYS A CA 1 ATOM 3056 C C . LYS A 1 374 ? -7.649 -24.346 -0.674 1.00 30.58 ? 374 LYS A C 1 ATOM 3057 O O . LYS A 1 374 ? -7.406 -25.486 -1.045 1.00 30.98 ? 374 LYS A O 1 ATOM 3058 C CB . LYS A 1 374 ? -7.556 -23.992 1.838 1.00 31.52 ? 374 LYS A CB 1 ATOM 3059 C CG . LYS A 1 374 ? -6.639 -23.854 3.032 1.00 34.69 ? 374 LYS A CG 1 ATOM 3060 C CD . LYS A 1 374 ? -7.292 -24.288 4.346 1.00 37.81 ? 374 LYS A CD 1 ATOM 3061 C CE . LYS A 1 374 ? -6.263 -24.233 5.473 1.00 40.22 ? 374 LYS A CE 1 ATOM 3062 N NZ . LYS A 1 374 ? -6.653 -25.061 6.659 1.00 43.85 ? 374 LYS A NZ 1 ATOM 3063 N N . LYS A 1 375 ? -8.599 -23.594 -1.239 1.00 29.32 ? 375 LYS A N 1 ATOM 3064 C CA . LYS A 1 375 ? -9.355 -24.054 -2.424 1.00 28.31 ? 375 LYS A CA 1 ATOM 3065 C C . LYS A 1 375 ? -8.607 -23.819 -3.754 1.00 26.83 ? 375 LYS A C 1 ATOM 3066 O O . LYS A 1 375 ? -9.141 -24.086 -4.822 1.00 26.13 ? 375 LYS A O 1 ATOM 3067 C CB . LYS A 1 375 ? -10.764 -23.417 -2.501 1.00 28.30 ? 375 LYS A CB 1 ATOM 3068 C CG . LYS A 1 375 ? -11.663 -23.610 -1.273 1.00 30.55 ? 375 LYS A CG 1 ATOM 3069 C CD . LYS A 1 375 ? -12.239 -25.020 -1.191 1.00 34.36 ? 375 LYS A CD 1 ATOM 3070 C CE . LYS A 1 375 ? -12.745 -25.355 0.238 1.00 36.96 ? 375 LYS A CE 1 ATOM 3071 N NZ . LYS A 1 375 ? -12.869 -26.852 0.473 1.00 37.96 ? 375 LYS A NZ 1 ATOM 3072 N N . ASP A 1 376 ? -7.382 -23.296 -3.669 1.00 25.91 ? 376 ASP A N 1 ATOM 3073 C CA . ASP A 1 376 ? -6.556 -22.991 -4.839 1.00 24.48 ? 376 ASP A CA 1 ATOM 3074 C C . ASP A 1 376 ? -7.287 -22.091 -5.885 1.00 23.27 ? 376 ASP A C 1 ATOM 3075 O O . ASP A 1 376 ? -7.304 -22.369 -7.085 1.00 22.71 ? 376 ASP A O 1 ATOM 3076 C CB . ASP A 1 376 ? -6.007 -24.300 -5.435 1.00 25.15 ? 376 ASP A CB 1 ATOM 3077 C CG . ASP A 1 376 ? -4.855 -24.079 -6.368 1.00 24.95 ? 376 ASP A CG 1 ATOM 3078 O OD1 . ASP A 1 376 ? -4.112 -23.094 -6.208 1.00 24.79 ? 376 ASP A OD1 1 ATOM 3079 O OD2 . ASP A 1 376 ? -4.693 -24.905 -7.287 1.00 29.37 ? 376 ASP A OD2 1 ATOM 3080 N N . ILE A 1 377 ? -7.898 -21.010 -5.397 1.00 21.52 ? 377 ILE A N 1 ATOM 3081 C CA . ILE A 1 377 ? -8.614 -20.078 -6.256 1.00 20.42 ? 377 ILE A CA 1 ATOM 3082 C C . ILE A 1 377 ? -7.737 -18.852 -6.396 1.00 18.89 ? 377 ILE A C 1 ATOM 3083 O O . ILE A 1 377 ? -7.562 -18.135 -5.405 1.00 18.43 ? 377 ILE A O 1 ATOM 3084 C CB . ILE A 1 377 ? -9.996 -19.645 -5.672 1.00 20.52 ? 377 ILE A CB 1 ATOM 3085 C CG1 . ILE A 1 377 ? -10.863 -20.874 -5.322 1.00 20.97 ? 377 ILE A CG1 1 ATOM 3086 C CG2 . ILE A 1 377 ? -10.710 -18.641 -6.647 1.00 18.87 ? 377 ILE A CG2 1 ATOM 3087 C CD1 . ILE A 1 377 ? -11.192 -21.785 -6.534 1.00 22.83 ? 377 ILE A CD1 1 ATOM 3088 N N . PRO A 1 378 ? -7.184 -18.621 -7.610 1.00 18.54 ? 378 PRO A N 1 ATOM 3089 C CA . PRO A 1 378 ? -6.218 -17.548 -7.824 1.00 17.73 ? 378 PRO A CA 1 ATOM 3090 C C . PRO A 1 378 ? -6.880 -16.169 -7.961 1.00 17.85 ? 378 PRO A C 1 ATOM 3091 O O . PRO A 1 378 ? -8.055 -16.070 -8.352 1.00 18.12 ? 378 PRO A O 1 ATOM 3092 C CB . PRO A 1 378 ? -5.561 -17.925 -9.164 1.00 17.95 ? 378 PRO A CB 1 ATOM 3093 C CG . PRO A 1 378 ? -6.701 -18.594 -9.948 1.00 17.97 ? 378 PRO A CG 1 ATOM 3094 C CD . PRO A 1 378 ? -7.538 -19.314 -8.881 1.00 18.80 ? 378 PRO A CD 1 ATOM 3095 N N . ILE A 1 379 ? -6.106 -15.128 -7.667 1.00 15.92 ? 379 ILE A N 1 ATOM 3096 C CA . ILE A 1 379 ? -6.446 -13.772 -8.102 1.00 16.17 ? 379 ILE A CA 1 ATOM 3097 C C . ILE A 1 379 ? -5.805 -13.477 -9.451 1.00 15.59 ? 379 ILE A C 1 ATOM 3098 O O . ILE A 1 379 ? -4.730 -13.966 -9.760 1.00 15.22 ? 379 ILE A O 1 ATOM 3099 C CB . ILE A 1 379 ? -6.046 -12.674 -7.061 1.00 15.27 ? 379 ILE A CB 1 ATOM 3100 C CG1 . ILE A 1 379 ? -4.536 -12.714 -6.725 1.00 15.64 ? 379 ILE A CG1 1 ATOM 3101 C CG2 . ILE A 1 379 ? -6.885 -12.811 -5.801 1.00 15.73 ? 379 ILE A CG2 1 ATOM 3102 C CD1 . ILE A 1 379 ? -4.090 -11.598 -5.710 1.00 13.32 ? 379 ILE A CD1 1 ATOM 3103 N N . GLU A 1 380 ? -6.476 -12.644 -10.235 1.00 15.99 ? 380 GLU A N 1 ATOM 3104 C CA . GLU A 1 380 ? -5.976 -12.170 -11.514 1.00 16.18 ? 380 GLU A CA 1 ATOM 3105 C C . GLU A 1 380 ? -5.520 -10.728 -11.290 1.00 17.43 ? 380 GLU A C 1 ATOM 3106 O O . GLU A 1 380 ? -6.352 -9.820 -11.064 1.00 15.62 ? 380 GLU A O 1 ATOM 3107 C CB . GLU A 1 380 ? -7.107 -12.184 -12.557 1.00 16.74 ? 380 GLU A CB 1 ATOM 3108 C CG . GLU A 1 380 ? -7.786 -13.526 -12.796 1.00 15.10 ? 380 GLU A CG 1 ATOM 3109 C CD . GLU A 1 380 ? -9.160 -13.358 -13.519 1.00 18.78 ? 380 GLU A CD 1 ATOM 3110 O OE1 . GLU A 1 380 ? -9.909 -12.386 -13.228 1.00 21.19 ? 380 GLU A OE1 1 ATOM 3111 O OE2 . GLU A 1 380 ? -9.492 -14.165 -14.392 1.00 18.06 ? 380 GLU A OE2 1 ATOM 3112 N N . VAL A 1 381 ? -4.200 -10.497 -11.328 1.00 17.67 ? 381 VAL A N 1 ATOM 3113 C CA . VAL A 1 381 ? -3.712 -9.168 -10.965 1.00 17.54 ? 381 VAL A CA 1 ATOM 3114 C C . VAL A 1 381 ? -3.377 -8.299 -12.187 1.00 16.83 ? 381 VAL A C 1 ATOM 3115 O O . VAL A 1 381 ? -2.717 -8.749 -13.119 1.00 14.86 ? 381 VAL A O 1 ATOM 3116 C CB . VAL A 1 381 ? -2.687 -9.166 -9.750 1.00 18.25 ? 381 VAL A CB 1 ATOM 3117 C CG1 . VAL A 1 381 ? -2.305 -10.572 -9.268 1.00 19.62 ? 381 VAL A CG1 1 ATOM 3118 C CG2 . VAL A 1 381 ? -1.508 -8.202 -9.918 1.00 16.73 ? 381 VAL A CG2 1 ATOM 3119 N N . CYS A 1 382 ? -3.911 -7.076 -12.193 1.00 16.83 ? 382 CYS A N 1 ATOM 3120 C CA . CYS A 1 382 ? -3.764 -6.186 -13.359 1.00 17.31 ? 382 CYS A CA 1 ATOM 3121 C C . CYS A 1 382 ? -3.184 -4.877 -12.839 1.00 16.73 ? 382 CYS A C 1 ATOM 3122 O O . CYS A 1 382 ? -3.942 -3.939 -12.514 1.00 15.92 ? 382 CYS A O 1 ATOM 3123 C CB . CYS A 1 382 ? -5.122 -5.959 -14.059 1.00 17.76 ? 382 CYS A CB 1 ATOM 3124 S SG . CYS A 1 382 ? -5.852 -7.513 -14.719 1.00 23.68 ? 382 CYS A SG 1 ATOM 3125 N N . PRO A 1 383 ? -1.834 -4.818 -12.716 1.00 15.83 ? 383 PRO A N 1 ATOM 3126 C CA . PRO A 1 383 ? -1.218 -3.718 -11.979 1.00 14.95 ? 383 PRO A CA 1 ATOM 3127 C C . PRO A 1 383 ? -1.417 -2.323 -12.616 1.00 15.26 ? 383 PRO A C 1 ATOM 3128 O O . PRO A 1 383 ? -1.640 -1.335 -11.887 1.00 14.22 ? 383 PRO A O 1 ATOM 3129 C CB . PRO A 1 383 ? 0.285 -4.111 -11.904 1.00 15.30 ? 383 PRO A CB 1 ATOM 3130 C CG . PRO A 1 383 ? 0.505 -5.107 -13.017 1.00 14.52 ? 383 PRO A CG 1 ATOM 3131 C CD . PRO A 1 383 ? -0.847 -5.825 -13.171 1.00 15.79 ? 383 PRO A CD 1 ATOM 3132 N N . ILE A 1 384 ? -1.306 -2.230 -13.940 1.00 14.17 ? 384 ILE A N 1 ATOM 3133 C CA . ILE A 1 384 ? -1.433 -0.948 -14.617 1.00 14.47 ? 384 ILE A CA 1 ATOM 3134 C C . ILE A 1 384 ? -2.848 -0.378 -14.461 1.00 14.59 ? 384 ILE A C 1 ATOM 3135 O O . ILE A 1 384 ? -3.042 0.810 -14.140 1.00 13.21 ? 384 ILE A O 1 ATOM 3136 C CB . ILE A 1 384 ? -0.969 -1.031 -16.096 1.00 14.62 ? 384 ILE A CB 1 ATOM 3137 C CG1 . ILE A 1 384 ? 0.561 -1.230 -16.117 1.00 14.54 ? 384 ILE A CG1 1 ATOM 3138 C CG2 . ILE A 1 384 ? -1.321 0.299 -16.828 1.00 13.09 ? 384 ILE A CG2 1 ATOM 3139 C CD1 . ILE A 1 384 ? 1.192 -1.699 -17.486 1.00 14.00 ? 384 ILE A CD1 1 ATOM 3140 N N . SER A 1 385 ? -3.828 -1.255 -14.627 1.00 14.02 ? 385 SER A N 1 ATOM 3141 C CA . SER A 1 385 ? -5.209 -0.868 -14.387 1.00 15.39 ? 385 SER A CA 1 ATOM 3142 C C . SER A 1 385 ? -5.388 -0.226 -12.998 1.00 15.41 ? 385 SER A C 1 ATOM 3143 O O . SER A 1 385 ? -5.991 0.849 -12.885 1.00 15.68 ? 385 SER A O 1 ATOM 3144 C CB . SER A 1 385 ? -6.116 -2.076 -14.521 1.00 15.39 ? 385 SER A CB 1 ATOM 3145 O OG . SER A 1 385 ? -7.426 -1.655 -14.275 1.00 19.24 ? 385 SER A OG 1 ATOM 3146 N N . ASN A 1 386 ? -4.854 -0.878 -11.956 1.00 14.39 ? 386 ASN A N 1 ATOM 3147 C CA . ASN A 1 386 ? -4.957 -0.367 -10.585 1.00 14.97 ? 386 ASN A CA 1 ATOM 3148 C C . ASN A 1 386 ? -4.295 0.997 -10.367 1.00 14.86 ? 386 ASN A C 1 ATOM 3149 O O . ASN A 1 386 ? -4.799 1.812 -9.565 1.00 14.28 ? 386 ASN A O 1 ATOM 3150 C CB . ASN A 1 386 ? -4.431 -1.365 -9.537 1.00 15.55 ? 386 ASN A CB 1 ATOM 3151 C CG . ASN A 1 386 ? -5.057 -2.772 -9.659 1.00 16.82 ? 386 ASN A CG 1 ATOM 3152 O OD1 . ASN A 1 386 ? -4.432 -3.776 -9.266 1.00 17.83 ? 386 ASN A OD1 1 ATOM 3153 N ND2 . ASN A 1 386 ? -6.264 -2.857 -10.224 1.00 14.97 ? 386 ASN A ND2 1 ATOM 3154 N N . GLN A 1 387 ? -3.171 1.236 -11.054 1.00 13.87 ? 387 GLN A N 1 ATOM 3155 C CA . GLN A 1 387 ? -2.494 2.524 -10.984 1.00 14.71 ? 387 GLN A CA 1 ATOM 3156 C C . GLN A 1 387 ? -3.286 3.618 -11.735 1.00 14.56 ? 387 GLN A C 1 ATOM 3157 O O . GLN A 1 387 ? -3.600 4.652 -11.163 1.00 16.18 ? 387 GLN A O 1 ATOM 3158 C CB . GLN A 1 387 ? -1.041 2.426 -11.493 1.00 14.07 ? 387 GLN A CB 1 ATOM 3159 C CG . GLN A 1 387 ? -0.248 3.701 -11.280 1.00 14.11 ? 387 GLN A CG 1 ATOM 3160 C CD . GLN A 1 387 ? 1.194 3.582 -11.744 1.00 14.13 ? 387 GLN A CD 1 ATOM 3161 O OE1 . GLN A 1 387 ? 1.462 3.367 -12.929 1.00 14.64 ? 387 GLN A OE1 1 ATOM 3162 N NE2 . GLN A 1 387 ? 2.123 3.745 -10.817 1.00 12.57 ? 387 GLN A NE2 1 ATOM 3163 N N . VAL A 1 388 ? -3.675 3.339 -12.972 1.00 14.89 ? 388 VAL A N 1 ATOM 3164 C CA . VAL A 1 388 ? -4.402 4.311 -13.820 1.00 15.68 ? 388 VAL A CA 1 ATOM 3165 C C . VAL A 1 388 ? -5.761 4.704 -13.243 1.00 15.89 ? 388 VAL A C 1 ATOM 3166 O O . VAL A 1 388 ? -6.120 5.888 -13.253 1.00 16.72 ? 388 VAL A O 1 ATOM 3167 C CB . VAL A 1 388 ? -4.503 3.815 -15.299 1.00 16.18 ? 388 VAL A CB 1 ATOM 3168 C CG1 . VAL A 1 388 ? -5.427 4.702 -16.152 1.00 17.09 ? 388 VAL A CG1 1 ATOM 3169 C CG2 . VAL A 1 388 ? -3.130 3.772 -15.925 1.00 17.05 ? 388 VAL A CG2 1 ATOM 3170 N N . LEU A 1 389 ? -6.483 3.732 -12.697 1.00 15.13 ? 389 LEU A N 1 ATOM 3171 C CA . LEU A 1 389 ? -7.786 4.016 -12.094 1.00 15.27 ? 389 LEU A CA 1 ATOM 3172 C C . LEU A 1 389 ? -7.659 4.390 -10.612 1.00 14.81 ? 389 LEU A C 1 ATOM 3173 O O . LEU A 1 389 ? -8.644 4.432 -9.882 1.00 15.44 ? 389 LEU A O 1 ATOM 3174 C CB . LEU A 1 389 ? -8.754 2.850 -12.320 1.00 15.05 ? 389 LEU A CB 1 ATOM 3175 C CG . LEU A 1 389 ? -8.877 2.468 -13.808 1.00 15.90 ? 389 LEU A CG 1 ATOM 3176 C CD1 . LEU A 1 389 ? -9.529 1.089 -13.989 1.00 17.12 ? 389 LEU A CD1 1 ATOM 3177 C CD2 . LEU A 1 389 ? -9.620 3.565 -14.606 1.00 17.57 ? 389 LEU A CD2 1 ATOM 3178 N N . LYS A 1 390 ? -6.432 4.678 -10.199 1.00 14.47 ? 390 LYS A N 1 ATOM 3179 C CA . LYS A 1 390 ? -6.143 5.395 -8.945 1.00 14.66 ? 390 LYS A CA 1 ATOM 3180 C C . LYS A 1 390 ? -6.336 4.607 -7.636 1.00 14.81 ? 390 LYS A C 1 ATOM 3181 O O . LYS A 1 390 ? -6.523 5.204 -6.563 1.00 15.95 ? 390 LYS A O 1 ATOM 3182 C CB . LYS A 1 390 ? -6.868 6.760 -8.895 1.00 14.78 ? 390 LYS A CB 1 ATOM 3183 C CG . LYS A 1 390 ? -6.535 7.693 -10.080 1.00 15.22 ? 390 LYS A CG 1 ATOM 3184 C CD . LYS A 1 390 ? -7.556 8.865 -10.195 1.00 15.25 ? 390 LYS A CD 1 ATOM 3185 C CE . LYS A 1 390 ? -7.392 9.862 -9.023 1.00 15.97 ? 390 LYS A CE 1 ATOM 3186 N NZ . LYS A 1 390 ? -6.014 10.452 -9.086 1.00 16.90 ? 390 LYS A NZ 1 ATOM 3187 N N . LEU A 1 391 ? -6.273 3.280 -7.719 1.00 13.59 ? 391 LEU A N 1 ATOM 3188 C CA . LEU A 1 391 ? -6.265 2.436 -6.495 1.00 13.18 ? 391 LEU A CA 1 ATOM 3189 C C . LEU A 1 391 ? -4.974 2.525 -5.673 1.00 13.46 ? 391 LEU A C 1 ATOM 3190 O O . LEU A 1 391 ? -5.005 2.387 -4.437 1.00 12.85 ? 391 LEU A O 1 ATOM 3191 C CB . LEU A 1 391 ? -6.549 0.992 -6.831 1.00 12.71 ? 391 LEU A CB 1 ATOM 3192 C CG . LEU A 1 391 ? -7.980 0.425 -6.756 1.00 16.82 ? 391 LEU A CG 1 ATOM 3193 C CD1 . LEU A 1 391 ? -9.128 1.439 -6.677 1.00 15.83 ? 391 LEU A CD1 1 ATOM 3194 C CD2 . LEU A 1 391 ? -8.184 -0.610 -7.862 1.00 17.73 ? 391 LEU A CD2 1 ATOM 3195 N N . VAL A 1 392 ? -3.846 2.730 -6.351 1.00 13.39 ? 392 VAL A N 1 ATOM 3196 C CA . VAL A 1 392 ? -2.578 2.902 -5.656 1.00 14.75 ? 392 VAL A CA 1 ATOM 3197 C C . VAL A 1 392 ? -1.666 3.748 -6.532 1.00 15.45 ? 392 VAL A C 1 ATOM 3198 O O . VAL A 1 392 ? -1.705 3.640 -7.772 1.00 16.11 ? 392 VAL A O 1 ATOM 3199 C CB . VAL A 1 392 ? -1.904 1.531 -5.276 1.00 14.53 ? 392 VAL A CB 1 ATOM 3200 C CG1 . VAL A 1 392 ? -1.676 0.685 -6.542 1.00 15.67 ? 392 VAL A CG1 1 ATOM 3201 C CG2 . VAL A 1 392 ? -0.596 1.779 -4.519 1.00 14.31 ? 392 VAL A CG2 1 ATOM 3202 N N . SER A 1 393 ? -0.867 4.608 -5.904 1.00 15.53 ? 393 SER A N 1 ATOM 3203 C CA . SER A 1 393 ? -0.104 5.588 -6.675 1.00 17.76 ? 393 SER A CA 1 ATOM 3204 C C . SER A 1 393 ? 1.288 5.030 -7.086 1.00 16.75 ? 393 SER A C 1 ATOM 3205 O O . SER A 1 393 ? 1.703 5.102 -8.241 1.00 17.58 ? 393 SER A O 1 ATOM 3206 C CB . SER A 1 393 ? -0.008 6.892 -5.857 1.00 18.25 ? 393 SER A CB 1 ATOM 3207 O OG . SER A 1 393 ? 0.790 7.815 -6.560 1.00 24.29 ? 393 SER A OG 1 ATOM 3208 N N . ASP A 1 394 ? 1.968 4.423 -6.131 1.00 16.58 ? 394 ASP A N 1 ATOM 3209 C CA . ASP A 1 394 ? 3.295 3.837 -6.303 1.00 15.23 ? 394 ASP A CA 1 ATOM 3210 C C . ASP A 1 394 ? 3.103 2.345 -6.240 1.00 15.35 ? 394 ASP A C 1 ATOM 3211 O O . ASP A 1 394 ? 2.709 1.833 -5.191 1.00 14.38 ? 394 ASP A O 1 ATOM 3212 C CB . ASP A 1 394 ? 4.129 4.259 -5.096 1.00 16.43 ? 394 ASP A CB 1 ATOM 3213 C CG . ASP A 1 394 ? 5.585 3.785 -5.148 1.00 15.48 ? 394 ASP A CG 1 ATOM 3214 O OD1 . ASP A 1 394 ? 5.939 2.928 -5.983 1.00 15.48 ? 394 ASP A OD1 1 ATOM 3215 O OD2 . ASP A 1 394 ? 6.385 4.302 -4.331 1.00 18.67 ? 394 ASP A OD2 1 ATOM 3216 N N . LEU A 1 395 ? 3.419 1.633 -7.329 1.00 13.91 ? 395 LEU A N 1 ATOM 3217 C CA . LEU A 1 395 ? 3.195 0.200 -7.378 1.00 13.36 ? 395 LEU A CA 1 ATOM 3218 C C . LEU A 1 395 ? 4.067 -0.613 -6.408 1.00 13.40 ? 395 LEU A C 1 ATOM 3219 O O . LEU A 1 395 ? 3.776 -1.783 -6.175 1.00 14.20 ? 395 LEU A O 1 ATOM 3220 C CB . LEU A 1 395 ? 3.318 -0.344 -8.814 1.00 13.00 ? 395 LEU A CB 1 ATOM 3221 C CG . LEU A 1 395 ? 2.150 0.021 -9.748 1.00 14.09 ? 395 LEU A CG 1 ATOM 3222 C CD1 . LEU A 1 395 ? 2.506 -0.176 -11.223 1.00 12.99 ? 395 LEU A CD1 1 ATOM 3223 C CD2 . LEU A 1 395 ? 0.936 -0.798 -9.397 1.00 11.55 ? 395 LEU A CD2 1 ATOM 3224 N N . ARG A 1 396 ? 5.119 -0.020 -5.843 1.00 13.03 ? 396 ARG A N 1 ATOM 3225 C CA . ARG A 1 396 ? 5.863 -0.714 -4.767 1.00 13.36 ? 396 ARG A CA 1 ATOM 3226 C C . ARG A 1 396 ? 4.930 -0.906 -3.539 1.00 13.49 ? 396 ARG A C 1 ATOM 3227 O O . ARG A 1 396 ? 5.159 -1.810 -2.751 1.00 12.48 ? 396 ARG A O 1 ATOM 3228 C CB . ARG A 1 396 ? 7.125 0.061 -4.374 1.00 13.96 ? 396 ARG A CB 1 ATOM 3229 C CG . ARG A 1 396 ? 8.216 0.172 -5.481 1.00 13.18 ? 396 ARG A CG 1 ATOM 3230 C CD . ARG A 1 396 ? 9.365 1.036 -5.003 1.00 15.39 ? 396 ARG A CD 1 ATOM 3231 N NE . ARG A 1 396 ? 8.930 2.420 -4.793 1.00 15.01 ? 396 ARG A NE 1 ATOM 3232 C CZ . ARG A 1 396 ? 9.726 3.440 -4.487 1.00 16.18 ? 396 ARG A CZ 1 ATOM 3233 N NH1 . ARG A 1 396 ? 11.042 3.264 -4.370 1.00 18.35 ? 396 ARG A NH1 1 ATOM 3234 N NH2 . ARG A 1 396 ? 9.211 4.650 -4.331 1.00 15.01 ? 396 ARG A NH2 1 ATOM 3235 N N . ASN A 1 397 ? 3.865 -0.084 -3.416 1.00 12.88 ? 397 ASN A N 1 ATOM 3236 C CA . ASN A 1 397 ? 2.847 -0.246 -2.334 1.00 13.17 ? 397 ASN A CA 1 ATOM 3237 C C . ASN A 1 397 ? 1.649 -1.134 -2.702 1.00 12.90 ? 397 ASN A C 1 ATOM 3238 O O . ASN A 1 397 ? 0.630 -1.173 -1.988 1.00 12.17 ? 397 ASN A O 1 ATOM 3239 C CB . ASN A 1 397 ? 2.285 1.129 -1.955 1.00 13.63 ? 397 ASN A CB 1 ATOM 3240 C CG . ASN A 1 397 ? 3.277 1.987 -1.186 1.00 16.71 ? 397 ASN A CG 1 ATOM 3241 O OD1 . ASN A 1 397 ? 3.360 3.219 -1.403 1.00 19.94 ? 397 ASN A OD1 1 ATOM 3242 N ND2 . ASN A 1 397 ? 4.024 1.367 -0.290 1.00 11.37 ? 397 ASN A ND2 1 ATOM 3243 N N . HIS A 1 398 ? 1.707 -1.794 -3.850 1.00 12.37 ? 398 HIS A N 1 ATOM 3244 C CA . HIS A 1 398 ? 0.584 -2.609 -4.260 1.00 11.73 ? 398 HIS A CA 1 ATOM 3245 C C . HIS A 1 398 ? 0.423 -3.762 -3.236 1.00 13.47 ? 398 HIS A C 1 ATOM 3246 O O . HIS A 1 398 ? 1.426 -4.404 -2.877 1.00 13.02 ? 398 HIS A O 1 ATOM 3247 C CB . HIS A 1 398 ? 0.825 -3.137 -5.696 1.00 11.49 ? 398 HIS A CB 1 ATOM 3248 C CG . HIS A 1 398 ? -0.399 -3.691 -6.350 1.00 11.10 ? 398 HIS A CG 1 ATOM 3249 N ND1 . HIS A 1 398 ? -1.033 -4.830 -5.896 1.00 10.28 ? 398 HIS A ND1 1 ATOM 3250 C CD2 . HIS A 1 398 ? -1.141 -3.235 -7.392 1.00 11.33 ? 398 HIS A CD2 1 ATOM 3251 C CE1 . HIS A 1 398 ? -2.097 -5.065 -6.648 1.00 11.48 ? 398 HIS A CE1 1 ATOM 3252 N NE2 . HIS A 1 398 ? -2.202 -4.095 -7.545 1.00 11.63 ? 398 HIS A NE2 1 ATOM 3253 N N . PRO A 1 399 ? -0.827 -4.021 -2.759 1.00 13.64 ? 399 PRO A N 1 ATOM 3254 C CA . PRO A 1 399 ? -1.061 -5.043 -1.729 1.00 14.70 ? 399 PRO A CA 1 ATOM 3255 C C . PRO A 1 399 ? -0.687 -6.469 -2.185 1.00 14.61 ? 399 PRO A C 1 ATOM 3256 O O . PRO A 1 399 ? -0.413 -7.315 -1.344 1.00 15.76 ? 399 PRO A O 1 ATOM 3257 C CB . PRO A 1 399 ? -2.561 -4.895 -1.396 1.00 13.80 ? 399 PRO A CB 1 ATOM 3258 C CG . PRO A 1 399 ? -3.166 -4.201 -2.611 1.00 15.33 ? 399 PRO A CG 1 ATOM 3259 C CD . PRO A 1 399 ? -2.060 -3.283 -3.102 1.00 13.86 ? 399 PRO A CD 1 ATOM 3260 N N . VAL A 1 400 ? -0.600 -6.714 -3.488 1.00 14.09 ? 400 VAL A N 1 ATOM 3261 C CA . VAL A 1 400 ? -0.189 -8.022 -3.986 1.00 14.42 ? 400 VAL A CA 1 ATOM 3262 C C . VAL A 1 400 ? 1.284 -8.376 -3.602 1.00 14.78 ? 400 VAL A C 1 ATOM 3263 O O . VAL A 1 400 ? 1.646 -9.559 -3.583 1.00 15.70 ? 400 VAL A O 1 ATOM 3264 C CB . VAL A 1 400 ? -0.548 -8.228 -5.522 1.00 14.05 ? 400 VAL A CB 1 ATOM 3265 C CG1 . VAL A 1 400 ? 0.107 -9.485 -6.116 1.00 15.73 ? 400 VAL A CG1 1 ATOM 3266 C CG2 . VAL A 1 400 ? -2.057 -8.392 -5.704 1.00 13.87 ? 400 VAL A CG2 1 ATOM 3267 N N . ALA A 1 401 ? 2.092 -7.384 -3.223 1.00 14.49 ? 401 ALA A N 1 ATOM 3268 C CA . ALA A 1 401 ? 3.490 -7.651 -2.779 1.00 16.32 ? 401 ALA A CA 1 ATOM 3269 C C . ALA A 1 401 ? 3.505 -8.674 -1.639 1.00 17.56 ? 401 ALA A C 1 ATOM 3270 O O . ALA A 1 401 ? 4.255 -9.644 -1.657 1.00 17.92 ? 401 ALA A O 1 ATOM 3271 C CB . ALA A 1 401 ? 4.242 -6.319 -2.362 1.00 14.82 ? 401 ALA A CB 1 ATOM 3272 N N . THR A 1 402 ? 2.610 -8.468 -0.674 1.00 18.63 ? 402 THR A N 1 ATOM 3273 C CA . THR A 1 402 ? 2.467 -9.315 0.493 1.00 19.71 ? 402 THR A CA 1 ATOM 3274 C C . THR A 1 402 ? 2.096 -10.759 0.102 1.00 20.09 ? 402 THR A C 1 ATOM 3275 O O . THR A 1 402 ? 2.617 -11.746 0.672 1.00 19.18 ? 402 THR A O 1 ATOM 3276 C CB . THR A 1 402 ? 1.409 -8.633 1.379 1.00 19.99 ? 402 THR A CB 1 ATOM 3277 O OG1 . THR A 1 402 ? 2.050 -7.899 2.422 1.00 26.21 ? 402 THR A OG1 1 ATOM 3278 C CG2 . THR A 1 402 ? 0.433 -9.527 1.900 1.00 21.32 ? 402 THR A CG2 1 ATOM 3279 N N . LEU A 1 403 ? 1.228 -10.860 -0.900 1.00 19.57 ? 403 LEU A N 1 ATOM 3280 C CA . LEU A 1 403 ? 0.750 -12.132 -1.434 1.00 19.11 ? 403 LEU A CA 1 ATOM 3281 C C . LEU A 1 403 ? 1.821 -12.840 -2.262 1.00 18.86 ? 403 LEU A C 1 ATOM 3282 O O . LEU A 1 403 ? 1.940 -14.066 -2.187 1.00 17.77 ? 403 LEU A O 1 ATOM 3283 C CB . LEU A 1 403 ? -0.489 -11.894 -2.287 1.00 18.83 ? 403 LEU A CB 1 ATOM 3284 C CG . LEU A 1 403 ? -1.895 -11.854 -1.651 1.00 21.30 ? 403 LEU A CG 1 ATOM 3285 C CD1 . LEU A 1 403 ? -1.942 -11.549 -0.173 1.00 17.59 ? 403 LEU A CD1 1 ATOM 3286 C CD2 . LEU A 1 403 ? -2.813 -10.929 -2.428 1.00 20.80 ? 403 LEU A CD2 1 ATOM 3287 N N . MET A 1 404 ? 2.591 -12.087 -3.057 1.00 18.48 ? 404 MET A N 1 ATOM 3288 C CA . MET A 1 404 ? 3.750 -12.675 -3.747 1.00 19.35 ? 404 MET A CA 1 ATOM 3289 C C . MET A 1 404 ? 4.762 -13.274 -2.763 1.00 19.92 ? 404 MET A C 1 ATOM 3290 O O . MET A 1 404 ? 5.356 -14.325 -3.046 1.00 19.98 ? 404 MET A O 1 ATOM 3291 C CB . MET A 1 404 ? 4.455 -11.675 -4.677 1.00 20.00 ? 404 MET A CB 1 ATOM 3292 C CG . MET A 1 404 ? 3.676 -11.360 -5.920 1.00 20.27 ? 404 MET A CG 1 ATOM 3293 S SD . MET A 1 404 ? 4.485 -10.122 -6.935 1.00 22.07 ? 404 MET A SD 1 ATOM 3294 C CE . MET A 1 404 ? 5.675 -11.124 -7.894 1.00 21.56 ? 404 MET A CE 1 ATOM 3295 N N . ALA A 1 405 ? 4.940 -12.625 -1.607 1.00 19.28 ? 405 ALA A N 1 ATOM 3296 C CA . ALA A 1 405 ? 5.933 -13.069 -0.614 1.00 19.82 ? 405 ALA A CA 1 ATOM 3297 C C . ALA A 1 405 ? 5.599 -14.411 0.045 1.00 20.19 ? 405 ALA A C 1 ATOM 3298 O O . ALA A 1 405 ? 6.501 -15.100 0.521 1.00 20.85 ? 405 ALA A O 1 ATOM 3299 C CB . ALA A 1 405 ? 6.158 -12.005 0.448 1.00 18.70 ? 405 ALA A CB 1 ATOM 3300 N N . THR A 1 406 ? 4.318 -14.775 0.065 1.00 20.73 ? 406 THR A N 1 ATOM 3301 C CA . THR A 1 406 ? 3.892 -16.062 0.595 1.00 21.55 ? 406 THR A CA 1 ATOM 3302 C C . THR A 1 406 ? 3.517 -17.059 -0.488 1.00 21.26 ? 406 THR A C 1 ATOM 3303 O O . THR A 1 406 ? 3.035 -18.158 -0.184 1.00 21.77 ? 406 THR A O 1 ATOM 3304 C CB . THR A 1 406 ? 2.716 -15.942 1.592 1.00 21.56 ? 406 THR A CB 1 ATOM 3305 O OG1 . THR A 1 406 ? 1.614 -15.281 0.970 1.00 24.83 ? 406 THR A OG1 1 ATOM 3306 C CG2 . THR A 1 406 ? 3.122 -15.194 2.836 1.00 21.72 ? 406 THR A CG2 1 ATOM 3307 N N . GLY A 1 407 ? 3.740 -16.698 -1.744 1.00 20.56 ? 407 GLY A N 1 ATOM 3308 C CA . GLY A 1 407 ? 3.481 -17.603 -2.854 1.00 20.66 ? 407 GLY A CA 1 ATOM 3309 C C . GLY A 1 407 ? 2.015 -17.904 -3.126 1.00 21.60 ? 407 GLY A C 1 ATOM 3310 O O . GLY A 1 407 ? 1.691 -18.991 -3.581 1.00 21.15 ? 407 GLY A O 1 ATOM 3311 N N . HIS A 1 408 ? 1.131 -16.935 -2.872 1.00 20.81 ? 408 HIS A N 1 ATOM 3312 C CA . HIS A 1 408 ? -0.315 -17.091 -3.117 1.00 20.17 ? 408 HIS A CA 1 ATOM 3313 C C . HIS A 1 408 ? -0.651 -17.396 -4.608 1.00 19.75 ? 408 HIS A C 1 ATOM 3314 O O . HIS A 1 408 ? 0.066 -16.937 -5.498 1.00 19.60 ? 408 HIS A O 1 ATOM 3315 C CB . HIS A 1 408 ? -1.019 -15.815 -2.649 1.00 19.85 ? 408 HIS A CB 1 ATOM 3316 C CG . HIS A 1 408 ? -2.496 -15.975 -2.488 1.00 19.66 ? 408 HIS A CG 1 ATOM 3317 N ND1 . HIS A 1 408 ? -3.074 -16.332 -1.292 1.00 17.92 ? 408 HIS A ND1 1 ATOM 3318 C CD2 . HIS A 1 408 ? -3.509 -15.830 -3.372 1.00 20.32 ? 408 HIS A CD2 1 ATOM 3319 C CE1 . HIS A 1 408 ? -4.385 -16.417 -1.450 1.00 20.61 ? 408 HIS A CE1 1 ATOM 3320 N NE2 . HIS A 1 408 ? -4.672 -16.131 -2.711 1.00 20.35 ? 408 HIS A NE2 1 ATOM 3321 N N . PRO A 1 409 ? -1.725 -18.184 -4.894 1.00 19.82 ? 409 PRO A N 1 ATOM 3322 C CA . PRO A 1 409 ? -2.093 -18.436 -6.310 1.00 19.18 ? 409 PRO A CA 1 ATOM 3323 C C . PRO A 1 409 ? -2.539 -17.159 -7.036 1.00 18.67 ? 409 PRO A C 1 ATOM 3324 O O . PRO A 1 409 ? -3.434 -16.464 -6.555 1.00 18.89 ? 409 PRO A O 1 ATOM 3325 C CB . PRO A 1 409 ? -3.289 -19.410 -6.203 1.00 19.33 ? 409 PRO A CB 1 ATOM 3326 C CG . PRO A 1 409 ? -3.840 -19.181 -4.806 1.00 19.83 ? 409 PRO A CG 1 ATOM 3327 C CD . PRO A 1 409 ? -2.603 -18.934 -3.973 1.00 19.74 ? 409 PRO A CD 1 ATOM 3328 N N . MET A 1 410 ? -1.906 -16.860 -8.166 1.00 17.44 ? 410 MET A N 1 ATOM 3329 C CA . MET A 1 410 ? -2.214 -15.660 -8.953 1.00 18.02 ? 410 MET A CA 1 ATOM 3330 C C . MET A 1 410 ? -1.749 -15.820 -10.373 1.00 17.64 ? 410 MET A C 1 ATOM 3331 O O . MET A 1 410 ? -0.846 -16.624 -10.661 1.00 17.90 ? 410 MET A O 1 ATOM 3332 C CB . MET A 1 410 ? -1.556 -14.401 -8.358 1.00 17.46 ? 410 MET A CB 1 ATOM 3333 C CG . MET A 1 410 ? -0.021 -14.460 -8.257 1.00 18.81 ? 410 MET A CG 1 ATOM 3334 S SD . MET A 1 410 ? 0.699 -12.940 -7.556 1.00 20.53 ? 410 MET A SD 1 ATOM 3335 C CE . MET A 1 410 ? 0.421 -13.207 -5.812 1.00 19.57 ? 410 MET A CE 1 ATOM 3336 N N . VAL A 1 411 ? -2.366 -15.028 -11.241 1.00 16.65 ? 411 VAL A N 1 ATOM 3337 C CA . VAL A 1 411 ? -1.976 -14.874 -12.627 1.00 16.46 ? 411 VAL A CA 1 ATOM 3338 C C . VAL A 1 411 ? -1.904 -13.375 -12.894 1.00 16.56 ? 411 VAL A C 1 ATOM 3339 O O . VAL A 1 411 ? -2.527 -12.559 -12.164 1.00 15.68 ? 411 VAL A O 1 ATOM 3340 C CB . VAL A 1 411 ? -2.968 -15.598 -13.611 1.00 16.05 ? 411 VAL A CB 1 ATOM 3341 C CG1 . VAL A 1 411 ? -3.010 -17.134 -13.301 1.00 17.31 ? 411 VAL A CG1 1 ATOM 3342 C CG2 . VAL A 1 411 ? -4.357 -15.016 -13.520 1.00 15.94 ? 411 VAL A CG2 1 ATOM 3343 N N . ILE A 1 412 ? -1.131 -12.999 -13.899 1.00 16.40 ? 412 ILE A N 1 ATOM 3344 C CA . ILE A 1 412 ? -1.020 -11.583 -14.282 1.00 15.69 ? 412 ILE A CA 1 ATOM 3345 C C . ILE A 1 412 ? -1.714 -11.378 -15.597 1.00 17.14 ? 412 ILE A C 1 ATOM 3346 O O . ILE A 1 412 ? -1.577 -12.207 -16.520 1.00 17.69 ? 412 ILE A O 1 ATOM 3347 C CB . ILE A 1 412 ? 0.473 -11.132 -14.445 1.00 16.62 ? 412 ILE A CB 1 ATOM 3348 C CG1 . ILE A 1 412 ? 1.325 -11.523 -13.196 1.00 14.47 ? 412 ILE A CG1 1 ATOM 3349 C CG2 . ILE A 1 412 ? 0.580 -9.600 -14.892 1.00 14.98 ? 412 ILE A CG2 1 ATOM 3350 C CD1 . ILE A 1 412 ? 0.889 -10.932 -11.804 1.00 15.63 ? 412 ILE A CD1 1 ATOM 3351 N N . SER A 1 413 ? -2.443 -10.272 -15.721 1.00 16.66 ? 413 SER A N 1 ATOM 3352 C CA . SER A 1 413 ? -3.010 -9.909 -17.041 1.00 17.45 ? 413 SER A CA 1 ATOM 3353 C C . SER A 1 413 ? -3.010 -8.377 -17.210 1.00 18.21 ? 413 SER A C 1 ATOM 3354 O O . SER A 1 413 ? -2.470 -7.673 -16.360 1.00 18.18 ? 413 SER A O 1 ATOM 3355 C CB . SER A 1 413 ? -4.409 -10.521 -17.227 1.00 16.85 ? 413 SER A CB 1 ATOM 3356 O OG . SER A 1 413 ? -4.763 -10.554 -18.601 1.00 17.53 ? 413 SER A OG 1 ATOM 3357 N N . SER A 1 414 ? -3.598 -7.866 -18.293 1.00 19.70 ? 414 SER A N 1 ATOM 3358 C CA . SER A 1 414 ? -3.544 -6.421 -18.575 1.00 20.72 ? 414 SER A CA 1 ATOM 3359 C C . SER A 1 414 ? -4.905 -5.679 -18.577 1.00 21.22 ? 414 SER A C 1 ATOM 3360 O O . SER A 1 414 ? -4.931 -4.439 -18.660 1.00 21.17 ? 414 SER A O 1 ATOM 3361 C CB . SER A 1 414 ? -2.807 -6.182 -19.885 1.00 20.56 ? 414 SER A CB 1 ATOM 3362 O OG . SER A 1 414 ? -3.382 -6.974 -20.912 1.00 21.25 ? 414 SER A OG 1 ATOM 3363 N N . ASP A 1 415 ? -6.017 -6.417 -18.517 1.00 21.34 ? 415 ASP A N 1 ATOM 3364 C CA . ASP A 1 415 ? -7.357 -5.810 -18.353 1.00 22.12 ? 415 ASP A CA 1 ATOM 3365 C C . ASP A 1 415 ? -7.864 -5.053 -19.609 1.00 22.17 ? 415 ASP A C 1 ATOM 3366 O O . ASP A 1 415 ? -8.567 -5.630 -20.433 1.00 22.14 ? 415 ASP A O 1 ATOM 3367 C CB . ASP A 1 415 ? -7.370 -4.907 -17.097 1.00 22.50 ? 415 ASP A CB 1 ATOM 3368 C CG . ASP A 1 415 ? -8.778 -4.571 -16.609 1.00 25.41 ? 415 ASP A CG 1 ATOM 3369 O OD1 . ASP A 1 415 ? -9.739 -5.152 -17.134 1.00 27.90 ? 415 ASP A OD1 1 ATOM 3370 O OD2 . ASP A 1 415 ? -8.930 -3.711 -15.705 1.00 29.27 ? 415 ASP A OD2 1 ATOM 3371 N N . ASP A 1 416 ? -7.481 -3.781 -19.755 1.00 22.23 ? 416 ASP A N 1 ATOM 3372 C CA . ASP A 1 416 ? -7.835 -2.947 -20.925 1.00 22.42 ? 416 ASP A CA 1 ATOM 3373 C C . ASP A 1 416 ? -6.594 -2.182 -21.433 1.00 21.03 ? 416 ASP A C 1 ATOM 3374 O O . ASP A 1 416 ? -6.577 -0.943 -21.412 1.00 21.09 ? 416 ASP A O 1 ATOM 3375 C CB . ASP A 1 416 ? -8.910 -1.912 -20.541 1.00 23.11 ? 416 ASP A CB 1 ATOM 3376 C CG . ASP A 1 416 ? -10.299 -2.503 -20.427 1.00 26.97 ? 416 ASP A CG 1 ATOM 3377 O OD1 . ASP A 1 416 ? -10.777 -3.143 -21.394 1.00 30.43 ? 416 ASP A OD1 1 ATOM 3378 O OD2 . ASP A 1 416 ? -10.932 -2.301 -19.368 1.00 31.58 ? 416 ASP A OD2 1 ATOM 3379 N N . PRO A 1 417 ? -5.559 -2.909 -21.882 1.00 20.08 ? 417 PRO A N 1 ATOM 3380 C CA . PRO A 1 417 ? -4.268 -2.235 -22.116 1.00 20.17 ? 417 PRO A CA 1 ATOM 3381 C C . PRO A 1 417 ? -4.337 -1.064 -23.103 1.00 20.05 ? 417 PRO A C 1 ATOM 3382 O O . PRO A 1 417 ? -3.669 -0.060 -22.902 1.00 20.17 ? 417 PRO A O 1 ATOM 3383 C CB . PRO A 1 417 ? -3.344 -3.365 -22.627 1.00 19.51 ? 417 PRO A CB 1 ATOM 3384 C CG . PRO A 1 417 ? -4.277 -4.483 -23.090 1.00 19.53 ? 417 PRO A CG 1 ATOM 3385 C CD . PRO A 1 417 ? -5.515 -4.352 -22.212 1.00 19.65 ? 417 PRO A CD 1 ATOM 3386 N N . ALA A 1 418 ? -5.149 -1.184 -24.140 1.00 20.37 ? 418 ALA A N 1 ATOM 3387 C CA . ALA A 1 418 ? -5.272 -0.121 -25.156 1.00 20.86 ? 418 ALA A CA 1 ATOM 3388 C C . ALA A 1 418 ? -5.721 1.225 -24.572 1.00 20.76 ? 418 ALA A C 1 ATOM 3389 O O . ALA A 1 418 ? -5.293 2.269 -25.052 1.00 20.71 ? 418 ALA A O 1 ATOM 3390 C CB . ALA A 1 418 ? -6.227 -0.570 -26.301 1.00 20.37 ? 418 ALA A CB 1 ATOM 3391 N N . MET A 1 419 ? -6.565 1.208 -23.535 1.00 21.14 ? 419 MET A N 1 ATOM 3392 C CA . MET A 1 419 ? -7.013 2.457 -22.889 1.00 21.37 ? 419 MET A CA 1 ATOM 3393 C C . MET A 1 419 ? -5.937 3.138 -22.063 1.00 20.81 ? 419 MET A C 1 ATOM 3394 O O . MET A 1 419 ? -6.064 4.333 -21.758 1.00 19.72 ? 419 MET A O 1 ATOM 3395 C CB . MET A 1 419 ? -8.265 2.270 -22.023 1.00 22.69 ? 419 MET A CB 1 ATOM 3396 C CG . MET A 1 419 ? -9.588 2.499 -22.786 1.00 27.02 ? 419 MET A CG 1 ATOM 3397 S SD . MET A 1 419 ? -10.277 0.952 -23.394 1.00 37.01 ? 419 MET A SD 1 ATOM 3398 C CE . MET A 1 419 ? -8.840 -0.044 -23.627 1.00 33.73 ? 419 MET A CE 1 ATOM 3399 N N . PHE A 1 420 ? -4.913 2.369 -21.686 1.00 21.17 ? 420 PHE A N 1 ATOM 3400 C CA . PHE A 1 420 ? -3.814 2.876 -20.852 1.00 21.21 ? 420 PHE A CA 1 ATOM 3401 C C . PHE A 1 420 ? -2.559 3.152 -21.657 1.00 21.29 ? 420 PHE A C 1 ATOM 3402 O O . PHE A 1 420 ? -1.565 3.605 -21.101 1.00 21.73 ? 420 PHE A O 1 ATOM 3403 C CB . PHE A 1 420 ? -3.426 1.887 -19.752 1.00 20.74 ? 420 PHE A CB 1 ATOM 3404 C CG . PHE A 1 420 ? -4.580 1.217 -19.055 1.00 20.71 ? 420 PHE A CG 1 ATOM 3405 C CD1 . PHE A 1 420 ? -5.702 1.925 -18.678 1.00 20.41 ? 420 PHE A CD1 1 ATOM 3406 C CD2 . PHE A 1 420 ? -4.507 -0.141 -18.740 1.00 19.44 ? 420 PHE A CD2 1 ATOM 3407 C CE1 . PHE A 1 420 ? -6.755 1.298 -18.020 1.00 21.90 ? 420 PHE A CE1 1 ATOM 3408 C CE2 . PHE A 1 420 ? -5.555 -0.777 -18.071 1.00 20.60 ? 420 PHE A CE2 1 ATOM 3409 C CZ . PHE A 1 420 ? -6.685 -0.053 -17.717 1.00 20.17 ? 420 PHE A CZ 1 ATOM 3410 N N . GLY A 1 421 ? -2.583 2.826 -22.945 1.00 21.78 ? 421 GLY A N 1 ATOM 3411 C CA . GLY A 1 421 ? -1.401 2.948 -23.804 1.00 21.76 ? 421 GLY A CA 1 ATOM 3412 C C . GLY A 1 421 ? -0.446 1.768 -23.687 1.00 22.01 ? 421 GLY A C 1 ATOM 3413 O O . GLY A 1 421 ? 0.718 1.876 -24.083 1.00 21.97 ? 421 GLY A O 1 ATOM 3414 N N . ALA A 1 422 ? -0.925 0.641 -23.148 1.00 20.65 ? 422 ALA A N 1 ATOM 3415 C CA . ALA A 1 422 ? -0.131 -0.573 -23.115 1.00 20.32 ? 422 ALA A CA 1 ATOM 3416 C C . ALA A 1 422 ? -0.531 -1.509 -24.255 1.00 20.06 ? 422 ALA A C 1 ATOM 3417 O O . ALA A 1 422 ? -1.420 -1.212 -25.022 1.00 20.97 ? 422 ALA A O 1 ATOM 3418 C CB . ALA A 1 422 ? -0.263 -1.295 -21.753 1.00 19.04 ? 422 ALA A CB 1 ATOM 3419 N N . LYS A 1 423 ? 0.124 -2.654 -24.339 1.00 20.58 ? 423 LYS A N 1 ATOM 3420 C CA . LYS A 1 423 ? -0.107 -3.618 -25.414 1.00 21.57 ? 423 LYS A CA 1 ATOM 3421 C C . LYS A 1 423 ? 0.274 -5.014 -24.881 1.00 20.46 ? 423 LYS A C 1 ATOM 3422 O O . LYS A 1 423 ? 1.302 -5.155 -24.229 1.00 20.22 ? 423 LYS A O 1 ATOM 3423 C CB . LYS A 1 423 ? 0.741 -3.178 -26.640 1.00 22.40 ? 423 LYS A CB 1 ATOM 3424 C CG . LYS A 1 423 ? 0.667 -4.068 -27.861 1.00 26.90 ? 423 LYS A CG 1 ATOM 3425 C CD . LYS A 1 423 ? 1.395 -3.409 -29.062 1.00 31.55 ? 423 LYS A CD 1 ATOM 3426 C CE . LYS A 1 423 ? 2.807 -3.002 -28.689 1.00 34.76 ? 423 LYS A CE 1 ATOM 3427 N NZ . LYS A 1 423 ? 3.683 -2.761 -29.878 1.00 37.15 ? 423 LYS A NZ 1 ATOM 3428 N N . GLY A 1 424 ? -0.575 -6.017 -25.131 1.00 19.99 ? 424 GLY A N 1 ATOM 3429 C CA . GLY A 1 424 ? -0.356 -7.398 -24.679 1.00 18.96 ? 424 GLY A CA 1 ATOM 3430 C C . GLY A 1 424 ? -0.220 -7.466 -23.165 1.00 19.07 ? 424 GLY A C 1 ATOM 3431 O O . GLY A 1 424 ? -0.972 -6.797 -22.446 1.00 18.76 ? 424 GLY A O 1 ATOM 3432 N N . LEU A 1 425 ? 0.755 -8.252 -22.699 1.00 17.92 ? 425 LEU A N 1 ATOM 3433 C CA . LEU A 1 425 ? 1.006 -8.511 -21.278 1.00 17.87 ? 425 LEU A CA 1 ATOM 3434 C C . LEU A 1 425 ? 2.351 -7.991 -20.729 1.00 17.09 ? 425 LEU A C 1 ATOM 3435 O O . LEU A 1 425 ? 2.492 -7.861 -19.505 1.00 16.65 ? 425 LEU A O 1 ATOM 3436 C CB . LEU A 1 425 ? 0.938 -10.027 -21.025 1.00 18.83 ? 425 LEU A CB 1 ATOM 3437 C CG . LEU A 1 425 ? -0.272 -10.662 -20.330 1.00 21.52 ? 425 LEU A CG 1 ATOM 3438 C CD1 . LEU A 1 425 ? -1.621 -9.931 -20.518 1.00 21.48 ? 425 LEU A CD1 1 ATOM 3439 C CD2 . LEU A 1 425 ? -0.379 -12.112 -20.651 1.00 20.27 ? 425 LEU A CD2 1 ATOM 3440 N N . SER A 1 426 ? 3.321 -7.706 -21.609 1.00 15.18 ? 426 SER A N 1 ATOM 3441 C CA . SER A 1 426 ? 4.704 -7.358 -21.171 1.00 16.12 ? 426 SER A CA 1 ATOM 3442 C C . SER A 1 426 ? 4.842 -6.187 -20.203 1.00 15.85 ? 426 SER A C 1 ATOM 3443 O O . SER A 1 426 ? 5.690 -6.232 -19.339 1.00 15.58 ? 426 SER A O 1 ATOM 3444 C CB . SER A 1 426 ? 5.661 -7.129 -22.366 1.00 14.82 ? 426 SER A CB 1 ATOM 3445 O OG . SER A 1 426 ? 5.794 -8.340 -23.119 1.00 16.52 ? 426 SER A OG 1 ATOM 3446 N N . TYR A 1 427 ? 4.051 -5.125 -20.389 1.00 16.66 ? 427 TYR A N 1 ATOM 3447 C CA . TYR A 1 427 ? 4.162 -3.960 -19.491 1.00 17.40 ? 427 TYR A CA 1 ATOM 3448 C C . TYR A 1 427 ? 3.716 -4.343 -18.094 1.00 16.58 ? 427 TYR A C 1 ATOM 3449 O O . TYR A 1 427 ? 4.358 -3.979 -17.130 1.00 16.87 ? 427 TYR A O 1 ATOM 3450 C CB . TYR A 1 427 ? 3.329 -2.789 -19.998 1.00 17.51 ? 427 TYR A CB 1 ATOM 3451 C CG . TYR A 1 427 ? 3.800 -2.214 -21.325 1.00 20.07 ? 427 TYR A CG 1 ATOM 3452 C CD1 . TYR A 1 427 ? 3.260 -2.688 -22.527 1.00 20.51 ? 427 TYR A CD1 1 ATOM 3453 C CD2 . TYR A 1 427 ? 4.769 -1.194 -21.374 1.00 20.29 ? 427 TYR A CD2 1 ATOM 3454 C CE1 . TYR A 1 427 ? 3.672 -2.184 -23.748 1.00 23.54 ? 427 TYR A CE1 1 ATOM 3455 C CE2 . TYR A 1 427 ? 5.178 -0.651 -22.602 1.00 22.98 ? 427 TYR A CE2 1 ATOM 3456 C CZ . TYR A 1 427 ? 4.627 -1.165 -23.780 1.00 24.56 ? 427 TYR A CZ 1 ATOM 3457 O OH . TYR A 1 427 ? 4.985 -0.681 -25.002 1.00 25.92 ? 427 TYR A OH 1 ATOM 3458 N N . ASP A 1 428 ? 2.611 -5.080 -18.007 1.00 16.34 ? 428 ASP A N 1 ATOM 3459 C CA . ASP A 1 428 ? 2.115 -5.594 -16.747 1.00 16.95 ? 428 ASP A CA 1 ATOM 3460 C C . ASP A 1 428 ? 3.088 -6.566 -16.077 1.00 16.77 ? 428 ASP A C 1 ATOM 3461 O O . ASP A 1 428 ? 3.309 -6.482 -14.867 1.00 15.48 ? 428 ASP A O 1 ATOM 3462 C CB . ASP A 1 428 ? 0.703 -6.155 -16.914 1.00 17.53 ? 428 ASP A CB 1 ATOM 3463 C CG . ASP A 1 428 ? -0.359 -5.009 -17.022 1.00 20.55 ? 428 ASP A CG 1 ATOM 3464 O OD1 . ASP A 1 428 ? -0.748 -4.464 -15.956 1.00 21.97 ? 428 ASP A OD1 1 ATOM 3465 O OD2 . ASP A 1 428 ? -0.756 -4.606 -18.161 1.00 22.97 ? 428 ASP A OD2 1 ATOM 3466 N N . PHE A 1 429 ? 3.722 -7.434 -16.861 1.00 14.81 ? 429 PHE A N 1 ATOM 3467 C CA . PHE A 1 429 ? 4.762 -8.282 -16.308 1.00 15.31 ? 429 PHE A CA 1 ATOM 3468 C C . PHE A 1 429 ? 5.946 -7.467 -15.782 1.00 15.23 ? 429 PHE A C 1 ATOM 3469 O O . PHE A 1 429 ? 6.503 -7.826 -14.755 1.00 15.23 ? 429 PHE A O 1 ATOM 3470 C CB . PHE A 1 429 ? 5.252 -9.357 -17.320 1.00 14.70 ? 429 PHE A CB 1 ATOM 3471 C CG . PHE A 1 429 ? 4.586 -10.696 -17.174 1.00 15.56 ? 429 PHE A CG 1 ATOM 3472 C CD1 . PHE A 1 429 ? 3.287 -10.901 -17.645 1.00 16.38 ? 429 PHE A CD1 1 ATOM 3473 C CD2 . PHE A 1 429 ? 5.258 -11.765 -16.593 1.00 17.09 ? 429 PHE A CD2 1 ATOM 3474 C CE1 . PHE A 1 429 ? 2.671 -12.137 -17.559 1.00 15.92 ? 429 PHE A CE1 1 ATOM 3475 C CE2 . PHE A 1 429 ? 4.650 -12.996 -16.480 1.00 18.29 ? 429 PHE A CE2 1 ATOM 3476 C CZ . PHE A 1 429 ? 3.334 -13.187 -16.971 1.00 16.51 ? 429 PHE A CZ 1 ATOM 3477 N N . TYR A 1 430 ? 6.332 -6.380 -16.468 1.00 15.12 ? 430 TYR A N 1 ATOM 3478 C CA . TYR A 1 430 ? 7.426 -5.539 -15.975 1.00 15.04 ? 430 TYR A CA 1 ATOM 3479 C C . TYR A 1 430 ? 7.041 -4.914 -14.616 1.00 15.66 ? 430 TYR A C 1 ATOM 3480 O O . TYR A 1 430 ? 7.850 -4.891 -13.672 1.00 14.61 ? 430 TYR A O 1 ATOM 3481 C CB . TYR A 1 430 ? 7.772 -4.440 -17.003 1.00 15.76 ? 430 TYR A CB 1 ATOM 3482 C CG . TYR A 1 430 ? 8.710 -3.374 -16.470 1.00 16.99 ? 430 TYR A CG 1 ATOM 3483 C CD1 . TYR A 1 430 ? 8.211 -2.302 -15.718 1.00 20.49 ? 430 TYR A CD1 1 ATOM 3484 C CD2 . TYR A 1 430 ? 10.081 -3.423 -16.729 1.00 17.02 ? 430 TYR A CD2 1 ATOM 3485 C CE1 . TYR A 1 430 ? 9.046 -1.320 -15.219 1.00 19.72 ? 430 TYR A CE1 1 ATOM 3486 C CE2 . TYR A 1 430 ? 10.937 -2.440 -16.249 1.00 18.37 ? 430 TYR A CE2 1 ATOM 3487 C CZ . TYR A 1 430 ? 10.410 -1.395 -15.490 1.00 20.82 ? 430 TYR A CZ 1 ATOM 3488 O OH . TYR A 1 430 ? 11.215 -0.417 -15.002 1.00 20.30 ? 430 TYR A OH 1 ATOM 3489 N N . GLU A 1 431 ? 5.805 -4.412 -14.523 1.00 15.55 ? 431 GLU A N 1 ATOM 3490 C CA . GLU A 1 431 ? 5.352 -3.814 -13.256 1.00 16.07 ? 431 GLU A CA 1 ATOM 3491 C C . GLU A 1 431 ? 5.399 -4.828 -12.094 1.00 16.09 ? 431 GLU A C 1 ATOM 3492 O O . GLU A 1 431 ? 5.843 -4.498 -11.000 1.00 16.64 ? 431 GLU A O 1 ATOM 3493 C CB . GLU A 1 431 ? 3.959 -3.208 -13.391 1.00 14.67 ? 431 GLU A CB 1 ATOM 3494 C CG . GLU A 1 431 ? 3.814 -2.109 -14.487 1.00 16.08 ? 431 GLU A CG 1 ATOM 3495 C CD . GLU A 1 431 ? 4.394 -0.747 -14.125 1.00 18.36 ? 431 GLU A CD 1 ATOM 3496 O OE1 . GLU A 1 431 ? 5.423 -0.672 -13.407 1.00 16.09 ? 431 GLU A OE1 1 ATOM 3497 O OE2 . GLU A 1 431 ? 3.814 0.277 -14.584 1.00 18.07 ? 431 GLU A OE2 1 ATOM 3498 N N . VAL A 1 432 ? 4.927 -6.046 -12.322 1.00 16.82 ? 432 VAL A N 1 ATOM 3499 C CA . VAL A 1 432 ? 4.988 -7.089 -11.283 1.00 17.32 ? 432 VAL A CA 1 ATOM 3500 C C . VAL A 1 432 ? 6.432 -7.472 -10.934 1.00 18.24 ? 432 VAL A C 1 ATOM 3501 O O . VAL A 1 432 ? 6.828 -7.481 -9.754 1.00 19.03 ? 432 VAL A O 1 ATOM 3502 C CB . VAL A 1 432 ? 4.190 -8.333 -11.714 1.00 17.71 ? 432 VAL A CB 1 ATOM 3503 C CG1 . VAL A 1 432 ? 4.462 -9.508 -10.767 1.00 17.27 ? 432 VAL A CG1 1 ATOM 3504 C CG2 . VAL A 1 432 ? 2.702 -8.019 -11.741 1.00 16.99 ? 432 VAL A CG2 1 ATOM 3505 N N . PHE A 1 433 ? 7.226 -7.758 -11.963 1.00 18.25 ? 433 PHE A N 1 ATOM 3506 C CA . PHE A 1 433 ? 8.616 -8.251 -11.774 1.00 18.84 ? 433 PHE A CA 1 ATOM 3507 C C . PHE A 1 433 ? 9.552 -7.234 -11.137 1.00 19.21 ? 433 PHE A C 1 ATOM 3508 O O . PHE A 1 433 ? 10.415 -7.600 -10.315 1.00 19.72 ? 433 PHE A O 1 ATOM 3509 C CB . PHE A 1 433 ? 9.193 -8.714 -13.122 1.00 17.81 ? 433 PHE A CB 1 ATOM 3510 C CG . PHE A 1 433 ? 10.553 -9.339 -13.024 1.00 18.58 ? 433 PHE A CG 1 ATOM 3511 C CD1 . PHE A 1 433 ? 10.752 -10.512 -12.299 1.00 20.41 ? 433 PHE A CD1 1 ATOM 3512 C CD2 . PHE A 1 433 ? 11.638 -8.772 -13.683 1.00 20.57 ? 433 PHE A CD2 1 ATOM 3513 C CE1 . PHE A 1 433 ? 12.033 -11.106 -12.225 1.00 20.15 ? 433 PHE A CE1 1 ATOM 3514 C CE2 . PHE A 1 433 ? 12.934 -9.359 -13.610 1.00 20.69 ? 433 PHE A CE2 1 ATOM 3515 C CZ . PHE A 1 433 ? 13.124 -10.520 -12.886 1.00 17.97 ? 433 PHE A CZ 1 ATOM 3516 N N . MET A 1 434 ? 9.400 -5.961 -11.525 1.00 19.61 ? 434 MET A N 1 ATOM 3517 C CA . MET A 1 434 ? 10.257 -4.894 -11.020 1.00 19.94 ? 434 MET A CA 1 ATOM 3518 C C . MET A 1 434 ? 9.654 -4.189 -9.798 1.00 20.27 ? 434 MET A C 1 ATOM 3519 O O . MET A 1 434 ? 10.373 -3.914 -8.834 1.00 21.49 ? 434 MET A O 1 ATOM 3520 C CB . MET A 1 434 ? 10.605 -3.875 -12.133 1.00 19.52 ? 434 MET A CB 1 ATOM 3521 C CG . MET A 1 434 ? 11.389 -4.510 -13.297 1.00 21.32 ? 434 MET A CG 1 ATOM 3522 S SD . MET A 1 434 ? 13.096 -4.930 -12.800 1.00 22.37 ? 434 MET A SD 1 ATOM 3523 C CE . MET A 1 434 ? 13.802 -3.294 -12.671 1.00 21.15 ? 434 MET A CE 1 ATOM 3524 N N . GLY A 1 435 ? 8.351 -3.896 -9.831 1.00 20.20 ? 435 GLY A N 1 ATOM 3525 C CA . GLY A 1 435 ? 7.733 -3.050 -8.787 1.00 18.90 ? 435 GLY A CA 1 ATOM 3526 C C . GLY A 1 435 ? 7.076 -3.760 -7.604 1.00 18.57 ? 435 GLY A C 1 ATOM 3527 O O . GLY A 1 435 ? 7.235 -3.346 -6.467 1.00 19.61 ? 435 GLY A O 1 ATOM 3528 N N . ILE A 1 436 ? 6.302 -4.797 -7.875 1.00 17.20 ? 436 ILE A N 1 ATOM 3529 C CA . ILE A 1 436 ? 5.499 -5.433 -6.839 1.00 15.99 ? 436 ILE A CA 1 ATOM 3530 C C . ILE A 1 436 ? 6.276 -6.543 -6.142 1.00 15.75 ? 436 ILE A C 1 ATOM 3531 O O . ILE A 1 436 ? 6.194 -6.661 -4.936 1.00 15.98 ? 436 ILE A O 1 ATOM 3532 C CB . ILE A 1 436 ? 4.146 -5.930 -7.399 1.00 14.99 ? 436 ILE A CB 1 ATOM 3533 C CG1 . ILE A 1 436 ? 3.369 -4.747 -8.034 1.00 15.24 ? 436 ILE A CG1 1 ATOM 3534 C CG2 . ILE A 1 436 ? 3.303 -6.619 -6.299 1.00 13.35 ? 436 ILE A CG2 1 ATOM 3535 C CD1 . ILE A 1 436 ? 2.102 -5.187 -8.718 1.00 12.26 ? 436 ILE A CD1 1 ATOM 3536 N N . GLY A 1 437 ? 7.051 -7.333 -6.893 1.00 15.99 ? 437 GLY A N 1 ATOM 3537 C CA . GLY A 1 437 ? 7.765 -8.493 -6.317 1.00 15.79 ? 437 GLY A CA 1 ATOM 3538 C C . GLY A 1 437 ? 9.106 -8.152 -5.675 1.00 17.38 ? 437 GLY A C 1 ATOM 3539 O O . GLY A 1 437 ? 9.745 -9.017 -5.051 1.00 18.27 ? 437 GLY A O 1 ATOM 3540 N N . GLY A 1 438 ? 9.536 -6.905 -5.810 1.00 17.33 ? 438 GLY A N 1 ATOM 3541 C CA . GLY A 1 438 ? 10.793 -6.433 -5.212 1.00 18.19 ? 438 GLY A CA 1 ATOM 3542 C C . GLY A 1 438 ? 12.064 -6.925 -5.899 1.00 19.33 ? 438 GLY A C 1 ATOM 3543 O O . GLY A 1 438 ? 12.003 -7.587 -6.948 1.00 18.50 ? 438 GLY A O 1 ATOM 3544 N N . MET A 1 439 ? 13.215 -6.610 -5.293 1.00 20.34 ? 439 MET A N 1 ATOM 3545 C CA . MET A 1 439 ? 14.523 -6.909 -5.895 1.00 21.04 ? 439 MET A CA 1 ATOM 3546 C C . MET A 1 439 ? 14.830 -8.403 -6.018 1.00 21.14 ? 439 MET A C 1 ATOM 3547 O O . MET A 1 439 ? 15.601 -8.806 -6.892 1.00 21.01 ? 439 MET A O 1 ATOM 3548 C CB . MET A 1 439 ? 15.652 -6.199 -5.131 1.00 21.94 ? 439 MET A CB 1 ATOM 3549 C CG . MET A 1 439 ? 17.033 -6.276 -5.829 1.00 24.22 ? 439 MET A CG 1 ATOM 3550 S SD . MET A 1 439 ? 18.321 -5.400 -4.910 1.00 34.26 ? 439 MET A SD 1 ATOM 3551 C CE . MET A 1 439 ? 18.099 -3.802 -5.689 1.00 27.20 ? 439 MET A CE 1 ATOM 3552 N N . LYS A 1 440 ? 14.250 -9.224 -5.154 1.00 21.80 ? 440 LYS A N 1 ATOM 3553 C CA . LYS A 1 440 ? 14.577 -10.665 -5.167 1.00 22.04 ? 440 LYS A CA 1 ATOM 3554 C C . LYS A 1 440 ? 13.666 -11.539 -6.054 1.00 22.18 ? 440 LYS A C 1 ATOM 3555 O O . LYS A 1 440 ? 13.915 -12.756 -6.179 1.00 22.96 ? 440 LYS A O 1 ATOM 3556 C CB . LYS A 1 440 ? 14.648 -11.232 -3.737 1.00 22.55 ? 440 LYS A CB 1 ATOM 3557 C CG . LYS A 1 440 ? 15.844 -10.692 -2.896 1.00 23.73 ? 440 LYS A CG 1 ATOM 3558 C CD . LYS A 1 440 ? 16.020 -11.487 -1.625 1.00 28.08 ? 440 LYS A CD 1 ATOM 3559 C CE . LYS A 1 440 ? 17.225 -11.022 -0.784 1.00 29.41 ? 440 LYS A CE 1 ATOM 3560 N NZ . LYS A 1 440 ? 18.286 -10.467 -1.649 1.00 33.25 ? 440 LYS A NZ 1 ATOM 3561 N N . ALA A 1 441 ? 12.604 -10.955 -6.628 1.00 20.90 ? 441 ALA A N 1 ATOM 3562 C CA . ALA A 1 441 ? 11.843 -11.641 -7.691 1.00 20.85 ? 441 ALA A CA 1 ATOM 3563 C C . ALA A 1 441 ? 12.797 -11.986 -8.840 1.00 20.68 ? 441 ALA A C 1 ATOM 3564 O O . ALA A 1 441 ? 13.542 -11.133 -9.316 1.00 19.79 ? 441 ALA A O 1 ATOM 3565 C CB . ALA A 1 441 ? 10.655 -10.806 -8.202 1.00 19.94 ? 441 ALA A CB 1 ATOM 3566 N N . ASP A 1 442 ? 12.756 -13.248 -9.273 1.00 20.80 ? 442 ASP A N 1 ATOM 3567 C CA . ASP A 1 442 ? 13.769 -13.779 -10.183 1.00 20.51 ? 442 ASP A CA 1 ATOM 3568 C C . ASP A 1 442 ? 13.125 -14.579 -11.341 1.00 20.17 ? 442 ASP A C 1 ATOM 3569 O O . ASP A 1 442 ? 11.903 -14.549 -11.547 1.00 18.18 ? 442 ASP A O 1 ATOM 3570 C CB . ASP A 1 442 ? 14.816 -14.614 -9.375 1.00 20.60 ? 442 ASP A CB 1 ATOM 3571 C CG . ASP A 1 442 ? 14.251 -15.929 -8.834 1.00 21.91 ? 442 ASP A CG 1 ATOM 3572 O OD1 . ASP A 1 442 ? 13.040 -16.174 -8.970 1.00 22.84 ? 442 ASP A OD1 1 ATOM 3573 O OD2 . ASP A 1 442 ? 15.016 -16.735 -8.245 1.00 24.49 ? 442 ASP A OD2 1 ATOM 3574 N N . LEU A 1 443 ? 13.946 -15.287 -12.117 1.00 20.14 ? 443 LEU A N 1 ATOM 3575 C CA . LEU A 1 443 ? 13.425 -16.147 -13.181 1.00 19.89 ? 443 LEU A CA 1 ATOM 3576 C C . LEU A 1 443 ? 12.371 -17.168 -12.695 1.00 19.79 ? 443 LEU A C 1 ATOM 3577 O O . LEU A 1 443 ? 11.450 -17.484 -13.436 1.00 19.60 ? 443 LEU A O 1 ATOM 3578 C CB . LEU A 1 443 ? 14.574 -16.878 -13.886 1.00 20.40 ? 443 LEU A CB 1 ATOM 3579 C CG . LEU A 1 443 ? 14.284 -17.630 -15.195 1.00 20.53 ? 443 LEU A CG 1 ATOM 3580 C CD1 . LEU A 1 443 ? 13.957 -16.666 -16.318 1.00 20.47 ? 443 LEU A CD1 1 ATOM 3581 C CD2 . LEU A 1 443 ? 15.490 -18.533 -15.606 1.00 21.33 ? 443 LEU A CD2 1 ATOM 3582 N N . ARG A 1 444 ? 12.518 -17.692 -11.475 1.00 19.08 ? 444 ARG A N 1 ATOM 3583 C CA . ARG A 1 444 ? 11.533 -18.637 -10.931 1.00 19.66 ? 444 ARG A CA 1 ATOM 3584 C C . ARG A 1 444 ? 10.137 -17.986 -10.730 1.00 19.64 ? 444 ARG A C 1 ATOM 3585 O O . ARG A 1 444 ? 9.119 -18.620 -10.962 1.00 18.76 ? 444 ARG A O 1 ATOM 3586 C CB . ARG A 1 444 ? 12.011 -19.230 -9.611 1.00 19.65 ? 444 ARG A CB 1 ATOM 3587 C CG . ARG A 1 444 ? 13.280 -20.151 -9.685 1.00 22.76 ? 444 ARG A CG 1 ATOM 3588 C CD . ARG A 1 444 ? 13.760 -20.489 -8.277 1.00 24.50 ? 444 ARG A CD 1 ATOM 3589 N NE . ARG A 1 444 ? 14.992 -21.294 -8.283 1.00 27.69 ? 444 ARG A NE 1 ATOM 3590 C CZ . ARG A 1 444 ? 16.218 -20.799 -8.425 1.00 26.67 ? 444 ARG A CZ 1 ATOM 3591 N NH1 . ARG A 1 444 ? 16.413 -19.486 -8.564 1.00 26.74 ? 444 ARG A NH1 1 ATOM 3592 N NH2 . ARG A 1 444 ? 17.264 -21.610 -8.415 1.00 26.26 ? 444 ARG A NH2 1 ATOM 3593 N N . THR A 1 445 ? 10.130 -16.725 -10.285 1.00 19.64 ? 445 THR A N 1 ATOM 3594 C CA . THR A 1 445 ? 8.911 -15.912 -10.200 1.00 19.26 ? 445 THR A CA 1 ATOM 3595 C C . THR A 1 445 ? 8.230 -15.888 -11.564 1.00 19.19 ? 445 THR A C 1 ATOM 3596 O O . THR A 1 445 ? 7.034 -16.197 -11.675 1.00 18.85 ? 445 THR A O 1 ATOM 3597 C CB . THR A 1 445 ? 9.222 -14.462 -9.759 1.00 18.87 ? 445 THR A CB 1 ATOM 3598 O OG1 . THR A 1 445 ? 10.000 -14.503 -8.561 1.00 18.90 ? 445 THR A OG1 1 ATOM 3599 C CG2 . THR A 1 445 ? 7.898 -13.613 -9.510 1.00 18.76 ? 445 THR A CG2 1 ATOM 3600 N N . LEU A 1 446 ? 8.986 -15.517 -12.586 1.00 18.82 ? 446 LEU A N 1 ATOM 3601 C CA . LEU A 1 446 ? 8.433 -15.365 -13.936 1.00 19.63 ? 446 LEU A CA 1 ATOM 3602 C C . LEU A 1 446 ? 7.902 -16.673 -14.492 1.00 19.75 ? 446 LEU A C 1 ATOM 3603 O O . LEU A 1 446 ? 6.787 -16.732 -15.065 1.00 19.32 ? 446 LEU A O 1 ATOM 3604 C CB . LEU A 1 446 ? 9.468 -14.768 -14.883 1.00 19.27 ? 446 LEU A CB 1 ATOM 3605 C CG . LEU A 1 446 ? 9.978 -13.356 -14.565 1.00 19.76 ? 446 LEU A CG 1 ATOM 3606 C CD1 . LEU A 1 446 ? 11.135 -13.046 -15.499 1.00 19.59 ? 446 LEU A CD1 1 ATOM 3607 C CD2 . LEU A 1 446 ? 8.860 -12.292 -14.731 1.00 20.01 ? 446 LEU A CD2 1 ATOM 3608 N N . LYS A 1 447 ? 8.701 -17.726 -14.317 1.00 19.76 ? 447 LYS A N 1 ATOM 3609 C CA . LYS A 1 447 ? 8.341 -19.048 -14.809 1.00 20.02 ? 447 LYS A CA 1 ATOM 3610 C C . LYS A 1 447 ? 7.061 -19.519 -14.125 1.00 19.86 ? 447 LYS A C 1 ATOM 3611 O O . LYS A 1 447 ? 6.158 -20.040 -14.789 1.00 19.64 ? 447 LYS A O 1 ATOM 3612 C CB . LYS A 1 447 ? 9.474 -20.076 -14.569 1.00 19.82 ? 447 LYS A CB 1 ATOM 3613 C CG . LYS A 1 447 ? 9.305 -21.383 -15.405 1.00 21.61 ? 447 LYS A CG 1 ATOM 3614 C CD . LYS A 1 447 ? 10.446 -22.364 -15.132 1.00 22.46 ? 447 LYS A CD 1 ATOM 3615 C CE . LYS A 1 447 ? 10.399 -23.575 -16.056 1.00 23.95 ? 447 LYS A CE 1 ATOM 3616 N NZ . LYS A 1 447 ? 11.451 -24.547 -15.655 1.00 23.34 ? 447 LYS A NZ 1 ATOM 3617 N N . GLN A 1 448 ? 6.982 -19.332 -12.804 1.00 19.79 ? 448 GLN A N 1 ATOM 3618 C CA . GLN A 1 448 ? 5.771 -19.713 -12.047 1.00 19.80 ? 448 GLN A CA 1 ATOM 3619 C C . GLN A 1 448 ? 4.504 -18.947 -12.529 1.00 19.31 ? 448 GLN A C 1 ATOM 3620 O O . GLN A 1 448 ? 3.420 -19.530 -12.682 1.00 19.33 ? 448 GLN A O 1 ATOM 3621 C CB . GLN A 1 448 ? 5.976 -19.487 -10.541 1.00 19.94 ? 448 GLN A CB 1 ATOM 3622 C CG . GLN A 1 448 ? 4.880 -20.079 -9.651 1.00 21.77 ? 448 GLN A CG 1 ATOM 3623 C CD . GLN A 1 448 ? 4.877 -21.606 -9.682 1.00 25.98 ? 448 GLN A CD 1 ATOM 3624 O OE1 . GLN A 1 448 ? 5.843 -22.226 -9.267 1.00 29.51 ? 448 GLN A OE1 1 ATOM 3625 N NE2 . GLN A 1 448 ? 3.809 -22.207 -10.193 1.00 26.31 ? 448 GLN A NE2 1 ATOM 3626 N N . LEU A 1 449 ? 4.640 -17.638 -12.743 1.00 18.42 ? 449 LEU A N 1 ATOM 3627 C CA . LEU A 1 449 ? 3.518 -16.843 -13.240 1.00 17.65 ? 449 LEU A CA 1 ATOM 3628 C C . LEU A 1 449 ? 3.048 -17.334 -14.632 1.00 18.18 ? 449 LEU A C 1 ATOM 3629 O O . LEU A 1 449 ? 1.844 -17.408 -14.907 1.00 18.46 ? 449 LEU A O 1 ATOM 3630 C CB . LEU A 1 449 ? 3.889 -15.360 -13.267 1.00 17.27 ? 449 LEU A CB 1 ATOM 3631 C CG . LEU A 1 449 ? 4.008 -14.724 -11.872 1.00 16.12 ? 449 LEU A CG 1 ATOM 3632 C CD1 . LEU A 1 449 ? 4.615 -13.340 -11.950 1.00 16.31 ? 449 LEU A CD1 1 ATOM 3633 C CD2 . LEU A 1 449 ? 2.621 -14.726 -11.178 1.00 18.10 ? 449 LEU A CD2 1 ATOM 3634 N N . ALA A 1 450 ? 3.992 -17.691 -15.494 1.00 18.28 ? 450 ALA A N 1 ATOM 3635 C CA . ALA A 1 450 ? 3.645 -18.196 -16.834 1.00 18.81 ? 450 ALA A CA 1 ATOM 3636 C C . ALA A 1 450 ? 2.913 -19.547 -16.743 1.00 19.01 ? 450 ALA A C 1 ATOM 3637 O O . ALA A 1 450 ? 1.829 -19.748 -17.347 1.00 19.09 ? 450 ALA A O 1 ATOM 3638 C CB . ALA A 1 450 ? 4.901 -18.302 -17.692 1.00 18.22 ? 450 ALA A CB 1 ATOM 3639 N N . MET A 1 451 ? 3.472 -20.463 -15.966 1.00 19.48 ? 451 MET A N 1 ATOM 3640 C CA . MET A 1 451 ? 2.819 -21.769 -15.758 1.00 19.80 ? 451 MET A CA 1 ATOM 3641 C C . MET A 1 451 ? 1.442 -21.671 -15.096 1.00 19.68 ? 451 MET A C 1 ATOM 3642 O O . MET A 1 451 ? 0.501 -22.339 -15.547 1.00 19.50 ? 451 MET A O 1 ATOM 3643 C CB . MET A 1 451 ? 3.727 -22.753 -15.033 1.00 19.50 ? 451 MET A CB 1 ATOM 3644 C CG . MET A 1 451 ? 4.984 -23.082 -15.845 1.00 22.38 ? 451 MET A CG 1 ATOM 3645 S SD . MET A 1 451 ? 6.058 -24.301 -15.064 1.00 25.69 ? 451 MET A SD 1 ATOM 3646 C CE . MET A 1 451 ? 6.509 -23.508 -13.498 1.00 22.32 ? 451 MET A CE 1 ATOM 3647 N N . ASN A 1 452 ? 1.321 -20.821 -14.067 1.00 19.23 ? 452 ASN A N 1 ATOM 3648 C CA . ASN A 1 452 ? 0.023 -20.542 -13.435 1.00 19.12 ? 452 ASN A CA 1 ATOM 3649 C C . ASN A 1 452 ? -1.071 -20.143 -14.434 1.00 18.50 ? 452 ASN A C 1 ATOM 3650 O O . ASN A 1 452 ? -2.219 -20.534 -14.279 1.00 18.18 ? 452 ASN A O 1 ATOM 3651 C CB . ASN A 1 452 ? 0.143 -19.422 -12.366 1.00 19.00 ? 452 ASN A CB 1 ATOM 3652 C CG . ASN A 1 452 ? 0.793 -19.894 -11.065 1.00 20.96 ? 452 ASN A CG 1 ATOM 3653 O OD1 . ASN A 1 452 ? 1.216 -21.043 -10.936 1.00 22.74 ? 452 ASN A OD1 1 ATOM 3654 N ND2 . ASN A 1 452 ? 0.879 -18.988 -10.092 1.00 19.70 ? 452 ASN A ND2 1 ATOM 3655 N N . SER A 1 453 ? -0.720 -19.342 -15.437 1.00 18.40 ? 453 SER A N 1 ATOM 3656 C CA . SER A 1 453 ? -1.696 -18.871 -16.426 1.00 19.57 ? 453 SER A CA 1 ATOM 3657 C C . SER A 1 453 ? -2.218 -20.003 -17.310 1.00 19.86 ? 453 SER A C 1 ATOM 3658 O O . SER A 1 453 ? -3.321 -19.894 -17.901 1.00 17.98 ? 453 SER A O 1 ATOM 3659 C CB . SER A 1 453 ? -1.141 -17.731 -17.293 1.00 19.12 ? 453 SER A CB 1 ATOM 3660 O OG . SER A 1 453 ? -0.203 -18.220 -18.247 1.00 19.76 ? 453 SER A OG 1 ATOM 3661 N N . ILE A 1 454 ? -1.422 -21.074 -17.405 1.00 20.60 ? 454 ILE A N 1 ATOM 3662 C CA . ILE A 1 454 ? -1.877 -22.314 -18.042 1.00 21.48 ? 454 ILE A CA 1 ATOM 3663 C C . ILE A 1 454 ? -2.694 -23.147 -17.046 1.00 21.50 ? 454 ILE A C 1 ATOM 3664 O O . ILE A 1 454 ? -3.792 -23.615 -17.380 1.00 22.22 ? 454 ILE A O 1 ATOM 3665 C CB . ILE A 1 454 ? -0.687 -23.141 -18.662 1.00 21.93 ? 454 ILE A CB 1 ATOM 3666 C CG1 . ILE A 1 454 ? 0.005 -22.319 -19.746 1.00 23.20 ? 454 ILE A CG1 1 ATOM 3667 C CG2 . ILE A 1 454 ? -1.192 -24.476 -19.268 1.00 23.13 ? 454 ILE A CG2 1 ATOM 3668 C CD1 . ILE A 1 454 ? 1.323 -22.921 -20.237 1.00 28.22 ? 454 ILE A CD1 1 ATOM 3669 N N . LYS A 1 455 ? -2.174 -23.317 -15.832 1.00 21.09 ? 455 LYS A N 1 ATOM 3670 C CA . LYS A 1 455 ? -2.849 -24.101 -14.783 1.00 21.26 ? 455 LYS A CA 1 ATOM 3671 C C . LYS A 1 455 ? -4.299 -23.614 -14.490 1.00 21.53 ? 455 LYS A C 1 ATOM 3672 O O . LYS A 1 455 ? -5.224 -24.433 -14.341 1.00 20.79 ? 455 LYS A O 1 ATOM 3673 C CB . LYS A 1 455 ? -1.995 -24.132 -13.501 1.00 21.03 ? 455 LYS A CB 1 ATOM 3674 C CG . LYS A 1 455 ? -2.622 -24.884 -12.311 1.00 21.77 ? 455 LYS A CG 1 ATOM 3675 C CD . LYS A 1 455 ? -1.817 -24.696 -11.010 1.00 24.56 ? 455 LYS A CD 1 ATOM 3676 C CE . LYS A 1 455 ? -2.482 -25.445 -9.844 1.00 27.32 ? 455 LYS A CE 1 ATOM 3677 N NZ . LYS A 1 455 ? -1.938 -25.019 -8.527 1.00 31.31 ? 455 LYS A NZ 1 ATOM 3678 N N . TYR A 1 456 ? -4.490 -22.293 -14.453 1.00 20.76 ? 456 TYR A N 1 ATOM 3679 C CA . TYR A 1 456 ? -5.746 -21.693 -13.969 1.00 20.87 ? 456 TYR A CA 1 ATOM 3680 C C . TYR A 1 456 ? -6.685 -21.296 -15.088 1.00 21.05 ? 456 TYR A C 1 ATOM 3681 O O . TYR A 1 456 ? -7.764 -20.746 -14.838 1.00 21.52 ? 456 TYR A O 1 ATOM 3682 C CB . TYR A 1 456 ? -5.475 -20.506 -13.005 1.00 21.00 ? 456 TYR A CB 1 ATOM 3683 C CG . TYR A 1 456 ? -4.762 -20.917 -11.731 1.00 21.46 ? 456 TYR A CG 1 ATOM 3684 C CD1 . TYR A 1 456 ? -5.387 -21.745 -10.778 1.00 20.42 ? 456 TYR A CD1 1 ATOM 3685 C CD2 . TYR A 1 456 ? -3.455 -20.494 -11.479 1.00 22.34 ? 456 TYR A CD2 1 ATOM 3686 C CE1 . TYR A 1 456 ? -4.726 -22.122 -9.622 1.00 21.03 ? 456 TYR A CE1 1 ATOM 3687 C CE2 . TYR A 1 456 ? -2.778 -20.879 -10.320 1.00 22.53 ? 456 TYR A CE2 1 ATOM 3688 C CZ . TYR A 1 456 ? -3.413 -21.675 -9.404 1.00 21.39 ? 456 TYR A CZ 1 ATOM 3689 O OH . TYR A 1 456 ? -2.716 -22.047 -8.290 1.00 22.41 ? 456 TYR A OH 1 ATOM 3690 N N . SER A 1 457 ? -6.287 -21.586 -16.329 1.00 20.59 ? 457 SER A N 1 ATOM 3691 C CA . SER A 1 457 ? -7.187 -21.456 -17.454 1.00 20.27 ? 457 SER A CA 1 ATOM 3692 C C . SER A 1 457 ? -8.316 -22.483 -17.295 1.00 20.56 ? 457 SER A C 1 ATOM 3693 O O . SER A 1 457 ? -8.255 -23.381 -16.431 1.00 20.72 ? 457 SER A O 1 ATOM 3694 C CB . SER A 1 457 ? -6.451 -21.690 -18.789 1.00 20.83 ? 457 SER A CB 1 ATOM 3695 O OG . SER A 1 457 ? -6.135 -23.077 -18.936 1.00 20.96 ? 457 SER A OG 1 ATOM 3696 N N . THR A 1 458 ? -9.346 -22.307 -18.111 1.00 21.30 ? 458 THR A N 1 ATOM 3697 C CA . THR A 1 458 ? -10.537 -23.165 -18.145 1.00 21.48 ? 458 THR A CA 1 ATOM 3698 C C . THR A 1 458 ? -10.448 -24.242 -19.226 1.00 21.91 ? 458 THR A C 1 ATOM 3699 O O . THR A 1 458 ? -11.433 -24.906 -19.533 1.00 21.91 ? 458 THR A O 1 ATOM 3700 C CB . THR A 1 458 ? -11.844 -22.335 -18.338 1.00 20.44 ? 458 THR A CB 1 ATOM 3701 O OG1 . THR A 1 458 ? -11.893 -21.767 -19.654 1.00 20.93 ? 458 THR A OG1 1 ATOM 3702 C CG2 . THR A 1 458 ? -11.943 -21.241 -17.316 1.00 20.57 ? 458 THR A CG2 1 ATOM 3703 N N . LEU A 1 459 ? -9.272 -24.415 -19.808 1.00 21.97 ? 459 LEU A N 1 ATOM 3704 C CA . LEU A 1 459 ? -9.056 -25.506 -20.742 1.00 23.42 ? 459 LEU A CA 1 ATOM 3705 C C . LEU A 1 459 ? -9.181 -26.893 -20.088 1.00 24.14 ? 459 LEU A C 1 ATOM 3706 O O . LEU A 1 459 ? -8.950 -27.053 -18.888 1.00 24.12 ? 459 LEU A O 1 ATOM 3707 C CB . LEU A 1 459 ? -7.670 -25.361 -21.387 1.00 23.08 ? 459 LEU A CB 1 ATOM 3708 C CG . LEU A 1 459 ? -7.452 -24.081 -22.196 1.00 24.16 ? 459 LEU A CG 1 ATOM 3709 C CD1 . LEU A 1 459 ? -5.985 -23.888 -22.460 1.00 22.86 ? 459 LEU A CD1 1 ATOM 3710 C CD2 . LEU A 1 459 ? -8.244 -24.135 -23.515 1.00 24.53 ? 459 LEU A CD2 1 ATOM 3711 N N . LEU A 1 460 ? -9.531 -27.898 -20.888 1.00 25.72 ? 460 LEU A N 1 ATOM 3712 C CA . LEU A 1 460 ? -9.477 -29.309 -20.446 1.00 26.92 ? 460 LEU A CA 1 ATOM 3713 C C . LEU A 1 460 ? -8.074 -29.648 -19.982 1.00 27.90 ? 460 LEU A C 1 ATOM 3714 O O . LEU A 1 460 ? -7.108 -29.088 -20.502 1.00 27.56 ? 460 LEU A O 1 ATOM 3715 C CB . LEU A 1 460 ? -9.859 -30.239 -21.605 1.00 27.57 ? 460 LEU A CB 1 ATOM 3716 C CG . LEU A 1 460 ? -11.298 -30.129 -22.130 1.00 28.41 ? 460 LEU A CG 1 ATOM 3717 C CD1 . LEU A 1 460 ? -11.527 -31.167 -23.224 1.00 31.85 ? 460 LEU A CD1 1 ATOM 3718 C CD2 . LEU A 1 460 ? -12.295 -30.321 -20.993 1.00 29.80 ? 460 LEU A CD2 1 ATOM 3719 N N . GLU A 1 461 ? -7.955 -30.566 -19.022 1.00 29.04 ? 461 GLU A N 1 ATOM 3720 C CA . GLU A 1 461 ? -6.638 -30.989 -18.535 1.00 30.49 ? 461 GLU A CA 1 ATOM 3721 C C . GLU A 1 461 ? -5.749 -31.512 -19.655 1.00 30.26 ? 461 GLU A C 1 ATOM 3722 O O . GLU A 1 461 ? -4.531 -31.305 -19.641 1.00 30.80 ? 461 GLU A O 1 ATOM 3723 C CB . GLU A 1 461 ? -6.750 -32.032 -17.417 1.00 30.79 ? 461 GLU A CB 1 ATOM 3724 C CG . GLU A 1 461 ? -7.400 -31.531 -16.133 1.00 33.25 ? 461 GLU A CG 1 ATOM 3725 C CD . GLU A 1 461 ? -6.686 -30.326 -15.492 1.00 36.76 ? 461 GLU A CD 1 ATOM 3726 O OE1 . GLU A 1 461 ? -5.427 -30.304 -15.407 1.00 37.94 ? 461 GLU A OE1 1 ATOM 3727 O OE2 . GLU A 1 461 ? -7.401 -29.399 -15.053 1.00 36.85 ? 461 GLU A OE2 1 ATOM 3728 N N . SER A 1 462 ? -6.359 -32.169 -20.635 1.00 30.18 ? 462 SER A N 1 ATOM 3729 C CA . SER A 1 462 ? -5.610 -32.684 -21.779 1.00 29.90 ? 462 SER A CA 1 ATOM 3730 C C . SER A 1 462 ? -5.123 -31.525 -22.660 1.00 29.57 ? 462 SER A C 1 ATOM 3731 O O . SER A 1 462 ? -4.047 -31.601 -23.262 1.00 28.39 ? 462 SER A O 1 ATOM 3732 C CB . SER A 1 462 ? -6.463 -33.676 -22.578 1.00 29.82 ? 462 SER A CB 1 ATOM 3733 O OG . SER A 1 462 ? -7.433 -33.013 -23.390 1.00 31.87 ? 462 SER A OG 1 ATOM 3734 N N . GLU A 1 463 ? -5.921 -30.451 -22.732 1.00 28.69 ? 463 GLU A N 1 ATOM 3735 C CA . GLU A 1 463 ? -5.516 -29.280 -23.505 1.00 28.70 ? 463 GLU A CA 1 ATOM 3736 C C . GLU A 1 463 ? -4.407 -28.483 -22.796 1.00 28.04 ? 463 GLU A C 1 ATOM 3737 O O . GLU A 1 463 ? -3.533 -27.914 -23.454 1.00 27.80 ? 463 GLU A O 1 ATOM 3738 C CB . GLU A 1 463 ? -6.727 -28.414 -23.861 1.00 28.85 ? 463 GLU A CB 1 ATOM 3739 C CG . GLU A 1 463 ? -7.649 -29.109 -24.882 1.00 31.30 ? 463 GLU A CG 1 ATOM 3740 C CD . GLU A 1 463 ? -9.093 -28.613 -24.849 1.00 33.42 ? 463 GLU A CD 1 ATOM 3741 O OE1 . GLU A 1 463 ? -9.478 -27.875 -23.910 1.00 34.86 ? 463 GLU A OE1 1 ATOM 3742 O OE2 . GLU A 1 463 ? -9.852 -28.966 -25.776 1.00 35.30 ? 463 GLU A OE2 1 ATOM 3743 N N . LYS A 1 464 ? -4.442 -28.456 -21.464 1.00 27.85 ? 464 LYS A N 1 ATOM 3744 C CA . LYS A 1 464 ? -3.392 -27.802 -20.678 1.00 27.91 ? 464 LYS A CA 1 ATOM 3745 C C . LYS A 1 464 ? -2.044 -28.498 -20.873 1.00 28.81 ? 464 LYS A C 1 ATOM 3746 O O . LYS A 1 464 ? -1.013 -27.836 -20.992 1.00 28.55 ? 464 LYS A O 1 ATOM 3747 C CB . LYS A 1 464 ? -3.770 -27.758 -19.203 1.00 28.00 ? 464 LYS A CB 1 ATOM 3748 C CG . LYS A 1 464 ? -4.961 -26.839 -18.881 1.00 25.06 ? 464 LYS A CG 1 ATOM 3749 C CD . LYS A 1 464 ? -5.342 -27.002 -17.418 1.00 23.97 ? 464 LYS A CD 1 ATOM 3750 C CE . LYS A 1 464 ? -6.486 -26.090 -17.035 1.00 24.66 ? 464 LYS A CE 1 ATOM 3751 N NZ . LYS A 1 464 ? -6.812 -26.249 -15.588 1.00 24.09 ? 464 LYS A NZ 1 ATOM 3752 N N . ASN A 1 465 ? -2.061 -29.833 -20.926 1.00 29.34 ? 465 ASN A N 1 ATOM 3753 C CA . ASN A 1 465 ? -0.848 -30.615 -21.188 1.00 29.91 ? 465 ASN A CA 1 ATOM 3754 C C . ASN A 1 465 ? -0.220 -30.249 -22.534 1.00 29.26 ? 465 ASN A C 1 ATOM 3755 O O . ASN A 1 465 ? 0.984 -29.982 -22.611 1.00 29.25 ? 465 ASN A O 1 ATOM 3756 C CB . ASN A 1 465 ? -1.148 -32.118 -21.122 1.00 30.97 ? 465 ASN A CB 1 ATOM 3757 C CG . ASN A 1 465 ? -1.499 -32.582 -19.722 1.00 33.52 ? 465 ASN A CG 1 ATOM 3758 O OD1 . ASN A 1 465 ? -0.979 -32.068 -18.723 1.00 37.62 ? 465 ASN A OD1 1 ATOM 3759 N ND2 . ASN A 1 465 ? -2.392 -33.566 -19.638 1.00 36.37 ? 465 ASN A ND2 1 ATOM 3760 N N . THR A 1 466 ? -1.049 -30.201 -23.574 1.00 28.20 ? 466 THR A N 1 ATOM 3761 C CA . THR A 1 466 ? -0.625 -29.739 -24.906 1.00 28.08 ? 466 THR A CA 1 ATOM 3762 C C . THR A 1 466 ? -0.096 -28.288 -24.924 1.00 27.44 ? 466 THR A C 1 ATOM 3763 O O . THR A 1 466 ? 0.946 -27.996 -25.541 1.00 26.13 ? 466 THR A O 1 ATOM 3764 C CB . THR A 1 466 ? -1.774 -29.850 -25.927 1.00 28.22 ? 466 THR A CB 1 ATOM 3765 O OG1 . THR A 1 466 ? -2.241 -31.200 -25.969 1.00 30.22 ? 466 THR A OG1 1 ATOM 3766 C CG2 . THR A 1 466 ? -1.318 -29.417 -27.329 1.00 28.64 ? 466 THR A CG2 1 ATOM 3767 N N . PHE A 1 467 ? -0.842 -27.389 -24.276 1.00 26.19 ? 467 PHE A N 1 ATOM 3768 C CA . PHE A 1 467 ? -0.419 -26.011 -24.088 1.00 26.14 ? 467 PHE A CA 1 ATOM 3769 C C . PHE A 1 467 ? 0.969 -26.001 -23.418 1.00 26.36 ? 467 PHE A C 1 ATOM 3770 O O . PHE A 1 467 ? 1.895 -25.346 -23.915 1.00 26.00 ? 467 PHE A O 1 ATOM 3771 C CB . PHE A 1 467 ? -1.443 -25.284 -23.204 1.00 26.28 ? 467 PHE A CB 1 ATOM 3772 C CG . PHE A 1 467 ? -1.341 -23.773 -23.217 1.00 26.58 ? 467 PHE A CG 1 ATOM 3773 C CD1 . PHE A 1 467 ? -0.238 -23.109 -23.776 1.00 25.13 ? 467 PHE A CD1 1 ATOM 3774 C CD2 . PHE A 1 467 ? -2.361 -23.012 -22.619 1.00 25.93 ? 467 PHE A CD2 1 ATOM 3775 C CE1 . PHE A 1 467 ? -0.169 -21.703 -23.772 1.00 26.63 ? 467 PHE A CE1 1 ATOM 3776 C CE2 . PHE A 1 467 ? -2.302 -21.619 -22.605 1.00 26.28 ? 467 PHE A CE2 1 ATOM 3777 C CZ . PHE A 1 467 ? -1.206 -20.960 -23.178 1.00 26.97 ? 467 PHE A CZ 1 ATOM 3778 N N . MET A 1 468 ? 1.102 -26.732 -22.309 1.00 26.50 ? 468 MET A N 1 ATOM 3779 C CA . MET A 1 468 ? 2.357 -26.813 -21.556 1.00 28.24 ? 468 MET A CA 1 ATOM 3780 C C . MET A 1 468 ? 3.545 -27.280 -22.422 1.00 28.37 ? 468 MET A C 1 ATOM 3781 O O . MET A 1 468 ? 4.647 -26.711 -22.338 1.00 28.47 ? 468 MET A O 1 ATOM 3782 C CB . MET A 1 468 ? 2.184 -27.707 -20.329 1.00 28.30 ? 468 MET A CB 1 ATOM 3783 C CG . MET A 1 468 ? 3.268 -27.568 -19.263 1.00 33.37 ? 468 MET A CG 1 ATOM 3784 S SD . MET A 1 468 ? 3.381 -25.953 -18.431 1.00 37.25 ? 468 MET A SD 1 ATOM 3785 C CE . MET A 1 468 ? 1.787 -25.822 -17.643 1.00 37.26 ? 468 MET A CE 1 ATOM 3786 N N . GLU A 1 469 ? 3.308 -28.297 -23.256 1.00 28.13 ? 469 GLU A N 1 ATOM 3787 C CA . GLU A 1 469 ? 4.318 -28.764 -24.216 1.00 28.42 ? 469 GLU A CA 1 ATOM 3788 C C . GLU A 1 469 ? 4.722 -27.701 -25.243 1.00 26.79 ? 469 GLU A C 1 ATOM 3789 O O . GLU A 1 469 ? 5.922 -27.510 -25.503 1.00 26.11 ? 469 GLU A O 1 ATOM 3790 C CB . GLU A 1 469 ? 3.903 -30.094 -24.859 1.00 28.80 ? 469 GLU A CB 1 ATOM 3791 C CG . GLU A 1 469 ? 4.212 -31.239 -23.896 1.00 33.80 ? 469 GLU A CG 1 ATOM 3792 C CD . GLU A 1 469 ? 3.436 -32.535 -24.140 1.00 41.79 ? 469 GLU A CD 1 ATOM 3793 O OE1 . GLU A 1 469 ? 2.448 -32.550 -24.925 1.00 43.81 ? 469 GLU A OE1 1 ATOM 3794 O OE2 . GLU A 1 469 ? 3.831 -33.554 -23.508 1.00 43.71 ? 469 GLU A OE2 1 ATOM 3795 N N . ILE A 1 470 ? 3.740 -26.985 -25.782 1.00 25.35 ? 470 ILE A N 1 ATOM 3796 C CA . ILE A 1 470 ? 4.025 -25.883 -26.708 1.00 24.18 ? 470 ILE A CA 1 ATOM 3797 C C . ILE A 1 470 ? 4.815 -24.760 -25.998 1.00 24.15 ? 470 ILE A C 1 ATOM 3798 O O . ILE A 1 470 ? 5.821 -24.248 -26.519 1.00 23.86 ? 470 ILE A O 1 ATOM 3799 C CB . ILE A 1 470 ? 2.746 -25.334 -27.341 1.00 24.35 ? 470 ILE A CB 1 ATOM 3800 C CG1 . ILE A 1 470 ? 2.114 -26.372 -28.298 1.00 24.16 ? 470 ILE A CG1 1 ATOM 3801 C CG2 . ILE A 1 470 ? 3.017 -24.034 -28.089 1.00 22.09 ? 470 ILE A CG2 1 ATOM 3802 C CD1 . ILE A 1 470 ? 0.773 -25.918 -28.873 1.00 25.37 ? 470 ILE A CD1 1 ATOM 3803 N N . TRP A 1 471 ? 4.356 -24.375 -24.814 1.00 23.99 ? 471 TRP A N 1 ATOM 3804 C CA . TRP A 1 471 ? 5.038 -23.324 -24.064 1.00 24.22 ? 471 TRP A CA 1 ATOM 3805 C C . TRP A 1 471 ? 6.467 -23.722 -23.603 1.00 25.12 ? 471 TRP A C 1 ATOM 3806 O O . TRP A 1 471 ? 7.358 -22.886 -23.638 1.00 25.61 ? 471 TRP A O 1 ATOM 3807 C CB . TRP A 1 471 ? 4.167 -22.853 -22.890 1.00 23.81 ? 471 TRP A CB 1 ATOM 3808 C CG . TRP A 1 471 ? 4.877 -21.942 -21.931 1.00 22.49 ? 471 TRP A CG 1 ATOM 3809 C CD1 . TRP A 1 471 ? 4.916 -20.565 -21.958 1.00 20.45 ? 471 TRP A CD1 1 ATOM 3810 C CD2 . TRP A 1 471 ? 5.659 -22.350 -20.818 1.00 21.75 ? 471 TRP A CD2 1 ATOM 3811 N NE1 . TRP A 1 471 ? 5.690 -20.102 -20.915 1.00 21.63 ? 471 TRP A NE1 1 ATOM 3812 C CE2 . TRP A 1 471 ? 6.146 -21.180 -20.194 1.00 21.68 ? 471 TRP A CE2 1 ATOM 3813 C CE3 . TRP A 1 471 ? 5.988 -23.605 -20.269 1.00 22.30 ? 471 TRP A CE3 1 ATOM 3814 C CZ2 . TRP A 1 471 ? 6.950 -21.225 -19.057 1.00 21.40 ? 471 TRP A CZ2 1 ATOM 3815 C CZ3 . TRP A 1 471 ? 6.784 -23.647 -19.147 1.00 22.32 ? 471 TRP A CZ3 1 ATOM 3816 C CH2 . TRP A 1 471 ? 7.271 -22.466 -18.557 1.00 21.94 ? 471 TRP A CH2 1 ATOM 3817 N N . LYS A 1 472 ? 6.679 -24.973 -23.174 1.00 26.38 ? 472 LYS A N 1 ATOM 3818 C CA . LYS A 1 472 ? 8.014 -25.428 -22.703 1.00 27.55 ? 472 LYS A CA 1 ATOM 3819 C C . LYS A 1 472 ? 9.082 -25.272 -23.787 1.00 27.44 ? 472 LYS A C 1 ATOM 3820 O O . LYS A 1 472 ? 10.231 -24.848 -23.513 1.00 27.13 ? 472 LYS A O 1 ATOM 3821 C CB . LYS A 1 472 ? 7.968 -26.883 -22.182 1.00 27.89 ? 472 LYS A CB 1 ATOM 3822 C CG . LYS A 1 472 ? 9.266 -27.410 -21.472 1.00 31.10 ? 472 LYS A CG 1 ATOM 3823 C CD . LYS A 1 472 ? 9.647 -26.578 -20.201 1.00 36.63 ? 472 LYS A CD 1 ATOM 3824 C CE . LYS A 1 472 ? 10.946 -27.063 -19.504 1.00 38.28 ? 472 LYS A CE 1 ATOM 3825 N NZ . LYS A 1 472 ? 12.174 -26.906 -20.347 1.00 40.99 ? 472 LYS A NZ 1 ATOM 3826 N N . LYS A 1 473 ? 8.712 -25.624 -25.017 1.00 27.87 ? 473 LYS A N 1 ATOM 3827 C CA . LYS A 1 473 ? 9.600 -25.426 -26.159 1.00 27.91 ? 473 LYS A CA 1 ATOM 3828 C C . LYS A 1 473 ? 9.874 -23.953 -26.404 1.00 27.49 ? 473 LYS A C 1 ATOM 3829 O O . LYS A 1 473 ? 11.024 -23.580 -26.697 1.00 26.87 ? 473 LYS A O 1 ATOM 3830 C CB . LYS A 1 473 ? 9.045 -26.060 -27.431 1.00 28.47 ? 473 LYS A CB 1 ATOM 3831 C CG . LYS A 1 473 ? 9.386 -27.532 -27.594 1.00 30.43 ? 473 LYS A CG 1 ATOM 3832 C CD . LYS A 1 473 ? 9.434 -27.894 -29.078 1.00 36.08 ? 473 LYS A CD 1 ATOM 3833 C CE . LYS A 1 473 ? 9.232 -29.378 -29.303 1.00 39.74 ? 473 LYS A CE 1 ATOM 3834 N NZ . LYS A 1 473 ? 7.924 -29.857 -28.715 1.00 41.99 ? 473 LYS A NZ 1 ATOM 3835 N N . ARG A 1 474 ? 8.845 -23.108 -26.275 1.00 26.51 ? 474 ARG A N 1 ATOM 3836 C CA . ARG A 1 474 ? 9.069 -21.651 -26.414 1.00 25.51 ? 474 ARG A CA 1 ATOM 3837 C C . ARG A 1 474 ? 9.923 -21.099 -25.268 1.00 24.83 ? 474 ARG A C 1 ATOM 3838 O O . ARG A 1 474 ? 10.741 -20.203 -25.482 1.00 24.36 ? 474 ARG A O 1 ATOM 3839 C CB . ARG A 1 474 ? 7.763 -20.862 -26.544 1.00 26.10 ? 474 ARG A CB 1 ATOM 3840 C CG . ARG A 1 474 ? 7.198 -20.909 -27.972 1.00 26.64 ? 474 ARG A CG 1 ATOM 3841 C CD . ARG A 1 474 ? 6.168 -19.835 -28.231 1.00 28.93 ? 474 ARG A CD 1 ATOM 3842 N NE . ARG A 1 474 ? 5.697 -19.935 -29.610 1.00 28.79 ? 474 ARG A NE 1 ATOM 3843 C CZ . ARG A 1 474 ? 5.251 -18.926 -30.347 1.00 28.27 ? 474 ARG A CZ 1 ATOM 3844 N NH1 . ARG A 1 474 ? 5.162 -17.694 -29.850 1.00 26.44 ? 474 ARG A NH1 1 ATOM 3845 N NH2 . ARG A 1 474 ? 4.877 -19.166 -31.600 1.00 27.56 ? 474 ARG A NH2 1 ATOM 3846 N N . TRP A 1 475 ? 9.737 -21.664 -24.078 1.00 24.48 ? 475 TRP A N 1 ATOM 3847 C CA . TRP A 1 475 ? 10.501 -21.298 -22.890 1.00 25.44 ? 475 TRP A CA 1 ATOM 3848 C C . TRP A 1 475 ? 11.982 -21.667 -23.071 1.00 26.04 ? 475 TRP A C 1 ATOM 3849 O O . TRP A 1 475 ? 12.867 -20.896 -22.734 1.00 26.30 ? 475 TRP A O 1 ATOM 3850 C CB . TRP A 1 475 ? 9.922 -21.969 -21.646 1.00 24.61 ? 475 TRP A CB 1 ATOM 3851 C CG . TRP A 1 475 ? 10.685 -21.659 -20.377 1.00 24.51 ? 475 TRP A CG 1 ATOM 3852 C CD1 . TRP A 1 475 ? 11.620 -22.465 -19.757 1.00 23.27 ? 475 TRP A CD1 1 ATOM 3853 C CD2 . TRP A 1 475 ? 10.595 -20.469 -19.577 1.00 23.86 ? 475 TRP A CD2 1 ATOM 3854 N NE1 . TRP A 1 475 ? 12.112 -21.848 -18.624 1.00 24.12 ? 475 TRP A NE1 1 ATOM 3855 C CE2 . TRP A 1 475 ? 11.508 -20.624 -18.485 1.00 23.48 ? 475 TRP A CE2 1 ATOM 3856 C CE3 . TRP A 1 475 ? 9.844 -19.284 -19.674 1.00 23.25 ? 475 TRP A CE3 1 ATOM 3857 C CZ2 . TRP A 1 475 ? 11.676 -19.648 -17.494 1.00 20.79 ? 475 TRP A CZ2 1 ATOM 3858 C CZ3 . TRP A 1 475 ? 10.020 -18.298 -18.675 1.00 22.10 ? 475 TRP A CZ3 1 ATOM 3859 C CH2 . TRP A 1 475 ? 10.928 -18.496 -17.605 1.00 22.38 ? 475 TRP A CH2 1 ATOM 3860 N N . ASP A 1 476 ? 12.242 -22.835 -23.627 1.00 27.04 ? 476 ASP A N 1 ATOM 3861 C CA . ASP A 1 476 ? 13.629 -23.255 -23.875 1.00 28.36 ? 476 ASP A CA 1 ATOM 3862 C C . ASP A 1 476 ? 14.408 -22.383 -24.852 1.00 28.38 ? 476 ASP A C 1 ATOM 3863 O O . ASP A 1 476 ? 15.568 -22.054 -24.580 1.00 29.36 ? 476 ASP A O 1 ATOM 3864 C CB . ASP A 1 476 ? 13.661 -24.734 -24.217 1.00 29.25 ? 476 ASP A CB 1 ATOM 3865 C CG . ASP A 1 476 ? 13.295 -25.575 -23.029 1.00 31.06 ? 476 ASP A CG 1 ATOM 3866 O OD1 . ASP A 1 476 ? 13.462 -25.095 -21.882 1.00 36.37 ? 476 ASP A OD1 1 ATOM 3867 O OD2 . ASP A 1 476 ? 12.831 -26.711 -23.201 1.00 35.16 ? 476 ASP A OD2 1 ATOM 3868 N N . LYS A 1 477 ? 13.760 -21.966 -25.941 1.00 28.18 ? 477 LYS A N 1 ATOM 3869 C CA . LYS A 1 477 ? 14.312 -21.016 -26.915 1.00 28.55 ? 477 LYS A CA 1 ATOM 3870 C C . LYS A 1 477 ? 14.535 -19.612 -26.326 1.00 28.01 ? 477 LYS A C 1 ATOM 3871 O O . LYS A 1 477 ? 15.506 -18.923 -26.666 1.00 28.37 ? 477 LYS A O 1 ATOM 3872 C CB . LYS A 1 477 ? 13.405 -20.947 -28.164 1.00 28.34 ? 477 LYS A CB 1 ATOM 3873 C CG . LYS A 1 477 ? 13.218 -19.537 -28.807 1.00 30.50 ? 477 LYS A CG 1 ATOM 3874 C CD . LYS A 1 477 ? 14.176 -19.289 -29.951 1.00 34.23 ? 477 LYS A CD 1 ATOM 3875 C CE . LYS A 1 477 ? 14.192 -17.818 -30.410 1.00 36.89 ? 477 LYS A CE 1 ATOM 3876 N NZ . LYS A 1 477 ? 12.819 -17.244 -30.634 1.00 37.81 ? 477 LYS A NZ 1 ATOM 3877 N N . PHE A 1 478 ? 13.641 -19.196 -25.441 1.00 26.87 ? 478 PHE A N 1 ATOM 3878 C CA . PHE A 1 478 ? 13.785 -17.926 -24.734 1.00 25.48 ? 478 PHE A CA 1 ATOM 3879 C C . PHE A 1 478 ? 15.039 -17.957 -23.837 1.00 25.54 ? 478 PHE A C 1 ATOM 3880 O O . PHE A 1 478 ? 15.880 -17.057 -23.906 1.00 25.64 ? 478 PHE A O 1 ATOM 3881 C CB . PHE A 1 478 ? 12.503 -17.676 -23.925 1.00 25.05 ? 478 PHE A CB 1 ATOM 3882 C CG . PHE A 1 478 ? 12.650 -16.679 -22.819 1.00 23.05 ? 478 PHE A CG 1 ATOM 3883 C CD1 . PHE A 1 478 ? 12.802 -15.311 -23.100 1.00 23.79 ? 478 PHE A CD1 1 ATOM 3884 C CD2 . PHE A 1 478 ? 12.589 -17.097 -21.500 1.00 22.89 ? 478 PHE A CD2 1 ATOM 3885 C CE1 . PHE A 1 478 ? 12.915 -14.381 -22.064 1.00 20.64 ? 478 PHE A CE1 1 ATOM 3886 C CE2 . PHE A 1 478 ? 12.695 -16.155 -20.423 1.00 22.17 ? 478 PHE A CE2 1 ATOM 3887 C CZ . PHE A 1 478 ? 12.861 -14.825 -20.707 1.00 19.71 ? 478 PHE A CZ 1 ATOM 3888 N N . ILE A 1 479 ? 15.146 -19.008 -23.025 1.00 25.76 ? 479 ILE A N 1 ATOM 3889 C CA . ILE A 1 479 ? 16.260 -19.244 -22.104 1.00 26.48 ? 479 ILE A CA 1 ATOM 3890 C C . ILE A 1 479 ? 17.602 -19.252 -22.849 1.00 27.57 ? 479 ILE A C 1 ATOM 3891 O O . ILE A 1 479 ? 18.542 -18.565 -22.443 1.00 27.02 ? 479 ILE A O 1 ATOM 3892 C CB . ILE A 1 479 ? 16.036 -20.565 -21.283 1.00 26.32 ? 479 ILE A CB 1 ATOM 3893 C CG1 . ILE A 1 479 ? 14.870 -20.406 -20.289 1.00 26.62 ? 479 ILE A CG1 1 ATOM 3894 C CG2 . ILE A 1 479 ? 17.285 -21.000 -20.536 1.00 27.07 ? 479 ILE A CG2 1 ATOM 3895 C CD1 . ILE A 1 479 ? 15.092 -19.383 -19.195 1.00 24.34 ? 479 ILE A CD1 1 ATOM 3896 N N . ALA A 1 480 ? 17.680 -20.015 -23.949 1.00 28.11 ? 480 ALA A N 1 ATOM 3897 C CA . ALA A 1 480 ? 18.883 -20.034 -24.774 1.00 28.91 ? 480 ALA A CA 1 ATOM 3898 C C . ALA A 1 480 ? 19.280 -18.638 -25.211 1.00 29.15 ? 480 ALA A C 1 ATOM 3899 O O . ALA A 1 480 ? 20.427 -18.256 -25.016 1.00 30.42 ? 480 ALA A O 1 ATOM 3900 C CB . ALA A 1 480 ? 18.743 -20.998 -25.981 1.00 27.92 ? 480 ALA A CB 1 ATOM 3901 N N . ASP A 1 481 ? 18.339 -17.875 -25.765 1.00 29.81 ? 481 ASP A N 1 ATOM 3902 C CA . ASP A 1 481 ? 18.583 -16.486 -26.144 1.00 30.66 ? 481 ASP A CA 1 ATOM 3903 C C . ASP A 1 481 ? 19.091 -15.585 -25.021 1.00 31.44 ? 481 ASP A C 1 ATOM 3904 O O . ASP A 1 481 ? 20.054 -14.826 -25.227 1.00 31.53 ? 481 ASP A O 1 ATOM 3905 C CB . ASP A 1 481 ? 17.342 -15.851 -26.756 1.00 31.20 ? 481 ASP A CB 1 ATOM 3906 C CG . ASP A 1 481 ? 16.995 -16.421 -28.115 1.00 33.90 ? 481 ASP A CG 1 ATOM 3907 O OD1 . ASP A 1 481 ? 17.868 -17.017 -28.792 1.00 36.19 ? 481 ASP A OD1 1 ATOM 3908 O OD2 . ASP A 1 481 ? 15.831 -16.259 -28.519 1.00 36.84 ? 481 ASP A OD2 1 ATOM 3909 N N . VAL A 1 482 ? 18.448 -15.637 -23.854 1.00 31.26 ? 482 VAL A N 1 ATOM 3910 C CA . VAL A 1 482 ? 18.870 -14.817 -22.704 1.00 31.07 ? 482 VAL A CA 1 ATOM 3911 C C . VAL A 1 482 ? 20.261 -15.252 -22.164 1.00 32.39 ? 482 VAL A C 1 ATOM 3912 O O . VAL A 1 482 ? 21.101 -14.402 -21.861 1.00 31.42 ? 482 VAL A O 1 ATOM 3913 C CB . VAL A 1 482 ? 17.801 -14.852 -21.567 1.00 30.88 ? 482 VAL A CB 1 ATOM 3914 C CG1 . VAL A 1 482 ? 18.312 -14.223 -20.259 1.00 29.35 ? 482 VAL A CG1 1 ATOM 3915 C CG2 . VAL A 1 482 ? 16.492 -14.190 -22.031 1.00 29.69 ? 482 VAL A CG2 1 ATOM 3916 N N . ALA A 1 483 ? 20.465 -16.566 -22.031 1.00 33.45 ? 483 ALA A N 1 ATOM 3917 C CA . ALA A 1 483 ? 21.727 -17.159 -21.564 1.00 35.26 ? 483 ALA A CA 1 ATOM 3918 C C . ALA A 1 483 ? 22.876 -16.770 -22.493 1.00 36.87 ? 483 ALA A C 1 ATOM 3919 O O . ALA A 1 483 ? 23.991 -16.516 -22.046 1.00 37.34 ? 483 ALA A O 1 ATOM 3920 C CB . ALA A 1 483 ? 21.609 -18.682 -21.479 1.00 34.76 ? 483 ALA A CB 1 ATOM 3921 N N . THR A 1 484 ? 22.585 -16.715 -23.789 1.00 38.19 ? 484 THR A N 1 ATOM 3922 C CA . THR A 1 484 ? 23.512 -16.182 -24.771 1.00 39.53 ? 484 THR A CA 1 ATOM 3923 C C . THR A 1 484 ? 22.805 -15.013 -25.439 1.00 39.61 ? 484 THR A C 1 ATOM 3924 O O . THR A 1 484 ? 23.380 -14.282 -26.240 1.00 40.31 ? 484 THR A O 1 ATOM 3925 C CB . THR A 1 484 ? 23.881 -17.233 -25.824 1.00 39.90 ? 484 THR A CB 1 ATOM 3926 O OG1 . THR A 1 484 ? 23.698 -18.553 -25.288 1.00 41.02 ? 484 THR A OG1 1 ATOM 3927 C CG2 . THR A 1 484 ? 25.317 -17.060 -26.248 1.00 41.29 ? 484 THR A CG2 1 ATOM 3928 N N . SER B 1 3 ? -25.394 -23.661 5.685 1.00 46.16 ? 3 SER B N 1 ATOM 3929 C CA . SER B 1 3 ? -24.052 -24.331 5.682 1.00 46.39 ? 3 SER B CA 1 ATOM 3930 C C . SER B 1 3 ? -23.027 -23.572 4.823 1.00 46.35 ? 3 SER B C 1 ATOM 3931 O O . SER B 1 3 ? -21.847 -23.495 5.176 1.00 46.02 ? 3 SER B O 1 ATOM 3932 C CB . SER B 1 3 ? -24.152 -25.778 5.218 1.00 46.43 ? 3 SER B CB 1 ATOM 3933 O OG . SER B 1 3 ? -22.937 -26.460 5.474 1.00 46.72 ? 3 SER B OG 1 ATOM 3934 N N . ILE B 1 4 ? -23.479 -23.042 3.686 1.00 45.84 ? 4 ILE B N 1 ATOM 3935 C CA . ILE B 1 4 ? -22.691 -22.053 2.964 1.00 45.44 ? 4 ILE B CA 1 ATOM 3936 C C . ILE B 1 4 ? -22.847 -20.740 3.726 1.00 44.74 ? 4 ILE B C 1 ATOM 3937 O O . ILE B 1 4 ? -21.875 -20.003 3.904 1.00 44.20 ? 4 ILE B O 1 ATOM 3938 C CB . ILE B 1 4 ? -23.103 -21.941 1.463 1.00 45.56 ? 4 ILE B CB 1 ATOM 3939 C CG1 . ILE B 1 4 ? -22.245 -22.890 0.615 1.00 45.48 ? 4 ILE B CG1 1 ATOM 3940 C CG2 . ILE B 1 4 ? -22.958 -20.507 0.948 1.00 46.23 ? 4 ILE B CG2 1 ATOM 3941 C CD1 . ILE B 1 4 ? -22.887 -23.321 -0.696 1.00 44.98 ? 4 ILE B CD1 1 ATOM 3942 N N . ASP B 1 5 ? -24.072 -20.487 4.200 1.00 43.81 ? 5 ASP B N 1 ATOM 3943 C CA . ASP B 1 5 ? -24.378 -19.352 5.070 1.00 43.29 ? 5 ASP B CA 1 ATOM 3944 C C . ASP B 1 5 ? -23.583 -19.393 6.361 1.00 42.19 ? 5 ASP B C 1 ATOM 3945 O O . ASP B 1 5 ? -23.187 -18.345 6.892 1.00 41.30 ? 5 ASP B O 1 ATOM 3946 C CB . ASP B 1 5 ? -25.869 -19.313 5.403 1.00 44.35 ? 5 ASP B CB 1 ATOM 3947 C CG . ASP B 1 5 ? -26.670 -18.507 4.402 1.00 46.26 ? 5 ASP B CG 1 ATOM 3948 O OD1 . ASP B 1 5 ? -27.477 -17.654 4.835 1.00 50.04 ? 5 ASP B OD1 1 ATOM 3949 O OD2 . ASP B 1 5 ? -26.495 -18.718 3.181 1.00 49.68 ? 5 ASP B OD2 1 ATOM 3950 N N . GLU B 1 6 ? -23.362 -20.611 6.859 1.00 40.81 ? 6 GLU B N 1 ATOM 3951 C CA . GLU B 1 6 ? -22.589 -20.832 8.068 1.00 39.77 ? 6 GLU B CA 1 ATOM 3952 C C . GLU B 1 6 ? -21.106 -20.614 7.829 1.00 37.67 ? 6 GLU B C 1 ATOM 3953 O O . GLU B 1 6 ? -20.435 -20.047 8.674 1.00 37.49 ? 6 GLU B O 1 ATOM 3954 C CB . GLU B 1 6 ? -22.820 -22.237 8.627 1.00 40.26 ? 6 GLU B CB 1 ATOM 3955 C CG . GLU B 1 6 ? -24.188 -22.428 9.280 1.00 43.01 ? 6 GLU B CG 1 ATOM 3956 C CD . GLU B 1 6 ? -24.358 -23.820 9.887 1.00 45.45 ? 6 GLU B CD 1 ATOM 3957 O OE1 . GLU B 1 6 ? -23.947 -24.819 9.252 1.00 46.42 ? 6 GLU B OE1 1 ATOM 3958 O OE2 . GLU B 1 6 ? -24.909 -23.906 11.007 1.00 47.26 ? 6 GLU B OE2 1 ATOM 3959 N N . THR B 1 7 ? -20.599 -21.073 6.689 1.00 35.90 ? 7 THR B N 1 ATOM 3960 C CA . THR B 1 7 ? -19.197 -20.845 6.314 1.00 33.76 ? 7 THR B CA 1 ATOM 3961 C C . THR B 1 7 ? -18.875 -19.350 6.257 1.00 32.55 ? 7 THR B C 1 ATOM 3962 O O . THR B 1 7 ? -17.858 -18.903 6.813 1.00 32.34 ? 7 THR B O 1 ATOM 3963 C CB . THR B 1 7 ? -18.868 -21.501 4.969 1.00 33.65 ? 7 THR B CB 1 ATOM 3964 O OG1 . THR B 1 7 ? -19.155 -22.898 5.060 1.00 33.43 ? 7 THR B OG1 1 ATOM 3965 C CG2 . THR B 1 7 ? -17.387 -21.314 4.601 1.00 32.44 ? 7 THR B CG2 1 ATOM 3966 N N . ARG B 1 8 ? -19.746 -18.593 5.593 1.00 30.68 ? 8 ARG B N 1 ATOM 3967 C CA . ARG B 1 8 ? -19.597 -17.147 5.468 1.00 30.40 ? 8 ARG B CA 1 ATOM 3968 C C . ARG B 1 8 ? -19.539 -16.503 6.849 1.00 30.58 ? 8 ARG B C 1 ATOM 3969 O O . ARG B 1 8 ? -18.744 -15.581 7.070 1.00 30.13 ? 8 ARG B O 1 ATOM 3970 C CB . ARG B 1 8 ? -20.745 -16.541 4.644 1.00 29.83 ? 8 ARG B CB 1 ATOM 3971 C CG . ARG B 1 8 ? -20.568 -15.081 4.213 1.00 27.77 ? 8 ARG B CG 1 ATOM 3972 C CD . ARG B 1 8 ? -21.866 -14.530 3.643 1.00 27.85 ? 8 ARG B CD 1 ATOM 3973 N NE . ARG B 1 8 ? -21.737 -13.215 3.006 1.00 26.05 ? 8 ARG B NE 1 ATOM 3974 C CZ . ARG B 1 8 ? -21.831 -12.035 3.628 1.00 28.13 ? 8 ARG B CZ 1 ATOM 3975 N NH1 . ARG B 1 8 ? -22.035 -11.957 4.937 1.00 28.22 ? 8 ARG B NH1 1 ATOM 3976 N NH2 . ARG B 1 8 ? -21.697 -10.905 2.935 1.00 28.12 ? 8 ARG B NH2 1 ATOM 3977 N N . ALA B 1 9 ? -20.379 -16.984 7.774 1.00 29.75 ? 9 ALA B N 1 ATOM 3978 C CA . ALA B 1 9 ? -20.449 -16.384 9.105 1.00 29.94 ? 9 ALA B CA 1 ATOM 3979 C C . ALA B 1 9 ? -19.176 -16.689 9.888 1.00 29.92 ? 9 ALA B C 1 ATOM 3980 O O . ALA B 1 9 ? -18.662 -15.832 10.605 1.00 30.13 ? 9 ALA B O 1 ATOM 3981 C CB . ALA B 1 9 ? -21.714 -16.851 9.868 1.00 29.67 ? 9 ALA B CB 1 ATOM 3982 N N . HIS B 1 10 ? -18.673 -17.912 9.726 1.00 29.87 ? 10 HIS B N 1 ATOM 3983 C CA . HIS B 1 10 ? -17.480 -18.364 10.417 1.00 30.12 ? 10 HIS B CA 1 ATOM 3984 C C . HIS B 1 10 ? -16.250 -17.559 9.963 1.00 28.94 ? 10 HIS B C 1 ATOM 3985 O O . HIS B 1 10 ? -15.417 -17.163 10.776 1.00 28.56 ? 10 HIS B O 1 ATOM 3986 C CB . HIS B 1 10 ? -17.290 -19.876 10.215 1.00 30.59 ? 10 HIS B CB 1 ATOM 3987 C CG . HIS B 1 10 ? -15.931 -20.373 10.601 1.00 34.36 ? 10 HIS B CG 1 ATOM 3988 N ND1 . HIS B 1 10 ? -15.575 -20.634 11.907 1.00 38.27 ? 10 HIS B ND1 1 ATOM 3989 C CD2 . HIS B 1 10 ? -14.833 -20.639 9.852 1.00 37.48 ? 10 HIS B CD2 1 ATOM 3990 C CE1 . HIS B 1 10 ? -14.317 -21.037 11.948 1.00 37.81 ? 10 HIS B CE1 1 ATOM 3991 N NE2 . HIS B 1 10 ? -13.845 -21.051 10.713 1.00 38.79 ? 10 HIS B NE2 1 ATOM 3992 N N . LEU B 1 11 ? -16.157 -17.309 8.662 1.00 28.00 ? 11 LEU B N 1 ATOM 3993 C CA . LEU B 1 11 ? -15.017 -16.579 8.107 1.00 26.62 ? 11 LEU B CA 1 ATOM 3994 C C . LEU B 1 11 ? -15.017 -15.148 8.643 1.00 25.70 ? 11 LEU B C 1 ATOM 3995 O O . LEU B 1 11 ? -13.972 -14.650 9.062 1.00 25.01 ? 11 LEU B O 1 ATOM 3996 C CB . LEU B 1 11 ? -14.988 -16.669 6.562 1.00 26.08 ? 11 LEU B CB 1 ATOM 3997 C CG . LEU B 1 11 ? -14.668 -18.078 6.004 1.00 26.58 ? 11 LEU B CG 1 ATOM 3998 C CD1 . LEU B 1 11 ? -15.081 -18.254 4.546 1.00 26.09 ? 11 LEU B CD1 1 ATOM 3999 C CD2 . LEU B 1 11 ? -13.188 -18.488 6.159 1.00 27.67 ? 11 LEU B CD2 1 ATOM 4000 N N . LEU B 1 12 ? -16.192 -14.513 8.688 1.00 24.86 ? 12 LEU B N 1 ATOM 4001 C CA . LEU B 1 12 ? -16.295 -13.181 9.265 1.00 24.93 ? 12 LEU B CA 1 ATOM 4002 C C . LEU B 1 12 ? -16.033 -13.131 10.777 1.00 25.13 ? 12 LEU B C 1 ATOM 4003 O O . LEU B 1 12 ? -15.450 -12.155 11.264 1.00 24.95 ? 12 LEU B O 1 ATOM 4004 C CB . LEU B 1 12 ? -17.644 -12.522 8.941 1.00 25.26 ? 12 LEU B CB 1 ATOM 4005 C CG . LEU B 1 12 ? -17.919 -12.211 7.469 1.00 25.82 ? 12 LEU B CG 1 ATOM 4006 C CD1 . LEU B 1 12 ? -19.423 -11.963 7.288 1.00 27.49 ? 12 LEU B CD1 1 ATOM 4007 C CD2 . LEU B 1 12 ? -17.069 -11.023 6.939 1.00 24.68 ? 12 LEU B CD2 1 ATOM 4008 N N . LEU B 1 13 ? -16.470 -14.159 11.518 1.00 24.98 ? 13 LEU B N 1 ATOM 4009 C CA . LEU B 1 13 ? -16.210 -14.222 12.973 1.00 25.32 ? 13 LEU B CA 1 ATOM 4010 C C . LEU B 1 13 ? -14.722 -14.373 13.242 1.00 24.89 ? 13 LEU B C 1 ATOM 4011 O O . LEU B 1 13 ? -14.191 -13.726 14.146 1.00 25.02 ? 13 LEU B O 1 ATOM 4012 C CB . LEU B 1 13 ? -16.988 -15.366 13.671 1.00 25.22 ? 13 LEU B CB 1 ATOM 4013 C CG . LEU B 1 13 ? -16.841 -15.468 15.204 1.00 25.86 ? 13 LEU B CG 1 ATOM 4014 C CD1 . LEU B 1 13 ? -17.344 -14.217 15.925 1.00 22.83 ? 13 LEU B CD1 1 ATOM 4015 C CD2 . LEU B 1 13 ? -17.534 -16.746 15.764 1.00 26.81 ? 13 LEU B CD2 1 ATOM 4016 N N . LYS B 1 14 ? -14.069 -15.243 12.469 1.00 25.27 ? 14 LYS B N 1 ATOM 4017 C CA . LYS B 1 14 ? -12.627 -15.434 12.564 1.00 25.69 ? 14 LYS B CA 1 ATOM 4018 C C . LYS B 1 14 ? -11.860 -14.115 12.353 1.00 24.71 ? 14 LYS B C 1 ATOM 4019 O O . LYS B 1 14 ? -10.992 -13.762 13.157 1.00 24.70 ? 14 LYS B O 1 ATOM 4020 C CB . LYS B 1 14 ? -12.136 -16.480 11.560 1.00 26.40 ? 14 LYS B CB 1 ATOM 4021 C CG . LYS B 1 14 ? -10.788 -17.053 11.977 1.00 31.23 ? 14 LYS B CG 1 ATOM 4022 C CD . LYS B 1 14 ? -9.940 -17.572 10.819 1.00 36.91 ? 14 LYS B CD 1 ATOM 4023 C CE . LYS B 1 14 ? -10.358 -18.945 10.317 1.00 38.91 ? 14 LYS B CE 1 ATOM 4024 N NZ . LYS B 1 14 ? -9.261 -19.407 9.384 1.00 41.27 ? 14 LYS B NZ 1 ATOM 4025 N N . GLU B 1 15 ? -12.190 -13.388 11.285 1.00 24.17 ? 15 GLU B N 1 ATOM 4026 C CA . GLU B 1 15 ? -11.590 -12.058 11.039 1.00 23.44 ? 15 GLU B CA 1 ATOM 4027 C C . GLU B 1 15 ? -11.874 -11.050 12.148 1.00 23.27 ? 15 GLU B C 1 ATOM 4028 O O . GLU B 1 15 ? -11.012 -10.224 12.504 1.00 22.01 ? 15 GLU B O 1 ATOM 4029 C CB . GLU B 1 15 ? -12.008 -11.518 9.673 1.00 22.95 ? 15 GLU B CB 1 ATOM 4030 C CG . GLU B 1 15 ? -11.296 -12.306 8.570 1.00 22.29 ? 15 GLU B CG 1 ATOM 4031 C CD . GLU B 1 15 ? -11.475 -11.786 7.187 1.00 23.81 ? 15 GLU B CD 1 ATOM 4032 O OE1 . GLU B 1 15 ? -12.168 -10.777 6.996 1.00 23.17 ? 15 GLU B OE1 1 ATOM 4033 O OE2 . GLU B 1 15 ? -10.927 -12.422 6.256 1.00 27.03 ? 15 GLU B OE2 1 ATOM 4034 N N . LYS B 1 16 ? -13.082 -11.131 12.697 1.00 23.09 ? 16 LYS B N 1 ATOM 4035 C CA . LYS B 1 16 ? -13.456 -10.320 13.860 1.00 23.30 ? 16 LYS B CA 1 ATOM 4036 C C . LYS B 1 16 ? -12.585 -10.615 15.085 1.00 22.80 ? 16 LYS B C 1 ATOM 4037 O O . LYS B 1 16 ? -12.147 -9.684 15.756 1.00 23.22 ? 16 LYS B O 1 ATOM 4038 C CB . LYS B 1 16 ? -14.950 -10.501 14.190 1.00 23.15 ? 16 LYS B CB 1 ATOM 4039 C CG . LYS B 1 16 ? -15.502 -9.486 15.203 1.00 23.88 ? 16 LYS B CG 1 ATOM 4040 C CD . LYS B 1 16 ? -16.918 -9.899 15.625 1.00 28.46 ? 16 LYS B CD 1 ATOM 4041 C CE . LYS B 1 16 ? -17.710 -8.729 16.164 1.00 32.47 ? 16 LYS B CE 1 ATOM 4042 N NZ . LYS B 1 16 ? -17.093 -8.145 17.371 1.00 36.25 ? 16 LYS B NZ 1 ATOM 4043 N N . MET B 1 17 ? -12.325 -11.895 15.357 1.00 23.22 ? 17 MET B N 1 ATOM 4044 C CA . MET B 1 17 ? -11.537 -12.305 16.535 1.00 24.30 ? 17 MET B CA 1 ATOM 4045 C C . MET B 1 17 ? -10.042 -12.042 16.384 1.00 24.03 ? 17 MET B C 1 ATOM 4046 O O . MET B 1 17 ? -9.380 -11.705 17.368 1.00 23.42 ? 17 MET B O 1 ATOM 4047 C CB . MET B 1 17 ? -11.746 -13.796 16.875 1.00 24.58 ? 17 MET B CB 1 ATOM 4048 C CG . MET B 1 17 ? -13.172 -14.147 17.310 1.00 28.70 ? 17 MET B CG 1 ATOM 4049 S SD . MET B 1 17 ? -13.754 -13.123 18.686 1.00 37.67 ? 17 MET B SD 1 ATOM 4050 C CE . MET B 1 17 ? -14.811 -11.948 17.845 1.00 35.21 ? 17 MET B CE 1 ATOM 4051 N N . MET B 1 18 ? -9.510 -12.203 15.170 1.00 23.16 ? 18 MET B N 1 ATOM 4052 C CA . MET B 1 18 ? -8.068 -12.011 14.975 1.00 23.73 ? 18 MET B CA 1 ATOM 4053 C C . MET B 1 18 ? -7.557 -10.572 14.716 1.00 22.75 ? 18 MET B C 1 ATOM 4054 O O . MET B 1 18 ? -6.390 -10.289 14.999 1.00 22.93 ? 18 MET B O 1 ATOM 4055 C CB . MET B 1 18 ? -7.472 -13.050 14.014 1.00 24.54 ? 18 MET B CB 1 ATOM 4056 C CG . MET B 1 18 ? -8.036 -13.052 12.625 1.00 28.41 ? 18 MET B CG 1 ATOM 4057 S SD . MET B 1 18 ? -7.416 -14.445 11.611 1.00 35.81 ? 18 MET B SD 1 ATOM 4058 C CE . MET B 1 18 ? -8.675 -14.417 10.375 1.00 35.42 ? 18 MET B CE 1 ATOM 4059 N N . ARG B 1 19 ? -8.395 -9.651 14.228 1.00 21.76 ? 19 ARG B N 1 ATOM 4060 C CA . ARG B 1 19 ? -7.954 -8.249 14.160 1.00 22.02 ? 19 ARG B CA 1 ATOM 4061 C C . ARG B 1 19 ? -7.601 -7.712 15.542 1.00 22.23 ? 19 ARG B C 1 ATOM 4062 O O . ARG B 1 19 ? -8.040 -8.253 16.573 1.00 21.69 ? 19 ARG B O 1 ATOM 4063 C CB . ARG B 1 19 ? -8.915 -7.294 13.398 1.00 22.08 ? 19 ARG B CB 1 ATOM 4064 C CG . ARG B 1 19 ? -10.266 -7.030 14.036 1.00 22.97 ? 19 ARG B CG 1 ATOM 4065 C CD . ARG B 1 19 ? -11.045 -5.958 13.232 1.00 24.39 ? 19 ARG B CD 1 ATOM 4066 N NE . ARG B 1 19 ? -11.632 -6.517 12.018 1.00 26.76 ? 19 ARG B NE 1 ATOM 4067 C CZ . ARG B 1 19 ? -12.889 -6.958 11.903 1.00 28.78 ? 19 ARG B CZ 1 ATOM 4068 N NH1 . ARG B 1 19 ? -13.754 -6.861 12.914 1.00 28.05 ? 19 ARG B NH1 1 ATOM 4069 N NH2 . ARG B 1 19 ? -13.296 -7.475 10.756 1.00 28.54 ? 19 ARG B NH2 1 ATOM 4070 N N . LEU B 1 20 ? -6.771 -6.673 15.538 1.00 22.00 ? 20 LEU B N 1 ATOM 4071 C CA . LEU B 1 20 ? -6.221 -6.111 16.750 1.00 22.15 ? 20 LEU B CA 1 ATOM 4072 C C . LEU B 1 20 ? -7.366 -5.722 17.681 1.00 21.87 ? 20 LEU B C 1 ATOM 4073 O O . LEU B 1 20 ? -8.301 -5.003 17.272 1.00 19.89 ? 20 LEU B O 1 ATOM 4074 C CB . LEU B 1 20 ? -5.357 -4.899 16.410 1.00 22.62 ? 20 LEU B CB 1 ATOM 4075 C CG . LEU B 1 20 ? -4.313 -4.448 17.435 1.00 24.47 ? 20 LEU B CG 1 ATOM 4076 C CD1 . LEU B 1 20 ? -3.030 -4.082 16.737 1.00 27.38 ? 20 LEU B CD1 1 ATOM 4077 C CD2 . LEU B 1 20 ? -4.859 -3.248 18.182 1.00 26.63 ? 20 LEU B CD2 1 ATOM 4078 N N . GLY B 1 21 ? -7.296 -6.257 18.904 1.00 21.07 ? 21 GLY B N 1 ATOM 4079 C CA . GLY B 1 21 ? -8.275 -5.981 19.966 1.00 20.94 ? 21 GLY B CA 1 ATOM 4080 C C . GLY B 1 21 ? -9.517 -6.872 19.953 1.00 21.36 ? 21 GLY B C 1 ATOM 4081 O O . GLY B 1 21 ? -10.386 -6.767 20.847 1.00 20.68 ? 21 GLY B O 1 ATOM 4082 N N . GLY B 1 22 ? -9.602 -7.744 18.950 1.00 20.54 ? 22 GLY B N 1 ATOM 4083 C CA . GLY B 1 22 ? -10.820 -8.477 18.650 1.00 22.66 ? 22 GLY B CA 1 ATOM 4084 C C . GLY B 1 22 ? -11.275 -9.420 19.762 1.00 24.37 ? 22 GLY B C 1 ATOM 4085 O O . GLY B 1 22 ? -12.479 -9.694 19.908 1.00 24.08 ? 22 GLY B O 1 ATOM 4086 N N . ARG B 1 23 ? -10.327 -9.883 20.567 1.00 24.41 ? 23 ARG B N 1 ATOM 4087 C CA . ARG B 1 23 ? -10.655 -10.782 21.666 1.00 26.51 ? 23 ARG B CA 1 ATOM 4088 C C . ARG B 1 23 ? -10.907 -10.090 23.012 1.00 26.10 ? 23 ARG B C 1 ATOM 4089 O O . ARG B 1 23 ? -11.196 -10.770 24.000 1.00 26.89 ? 23 ARG B O 1 ATOM 4090 C CB . ARG B 1 23 ? -9.603 -11.903 21.777 1.00 26.75 ? 23 ARG B CB 1 ATOM 4091 C CG . ARG B 1 23 ? -9.778 -12.921 20.667 1.00 30.47 ? 23 ARG B CG 1 ATOM 4092 C CD . ARG B 1 23 ? -8.817 -14.095 20.767 1.00 36.00 ? 23 ARG B CD 1 ATOM 4093 N NE . ARG B 1 23 ? -9.241 -15.140 19.844 1.00 41.12 ? 23 ARG B NE 1 ATOM 4094 C CZ . ARG B 1 23 ? -8.558 -16.253 19.581 1.00 45.97 ? 23 ARG B CZ 1 ATOM 4095 N NH1 . ARG B 1 23 ? -7.378 -16.485 20.161 1.00 47.51 ? 23 ARG B NH1 1 ATOM 4096 N NH2 . ARG B 1 23 ? -9.058 -17.141 18.726 1.00 46.85 ? 23 ARG B NH2 1 ATOM 4097 N N . LEU B 1 24 ? -10.828 -8.752 23.042 1.00 24.62 ? 24 LEU B N 1 ATOM 4098 C CA . LEU B 1 24 ? -11.089 -7.982 24.259 1.00 23.97 ? 24 LEU B CA 1 ATOM 4099 C C . LEU B 1 24 ? -12.566 -8.001 24.602 1.00 24.55 ? 24 LEU B C 1 ATOM 4100 O O . LEU B 1 24 ? -13.441 -7.890 23.709 1.00 24.37 ? 24 LEU B O 1 ATOM 4101 C CB . LEU B 1 24 ? -10.617 -6.523 24.141 1.00 22.92 ? 24 LEU B CB 1 ATOM 4102 C CG . LEU B 1 24 ? -9.100 -6.239 24.148 1.00 22.13 ? 24 LEU B CG 1 ATOM 4103 C CD1 . LEU B 1 24 ? -8.829 -4.727 24.019 1.00 19.66 ? 24 LEU B CD1 1 ATOM 4104 C CD2 . LEU B 1 24 ? -8.376 -6.820 25.379 1.00 21.82 ? 24 LEU B CD2 1 ATOM 4105 N N . VAL B 1 25 ? -12.847 -8.089 25.899 1.00 23.96 ? 25 VAL B N 1 ATOM 4106 C CA . VAL B 1 25 ? -14.234 -8.159 26.351 1.00 24.09 ? 25 VAL B CA 1 ATOM 4107 C C . VAL B 1 25 ? -14.666 -6.801 26.885 1.00 23.78 ? 25 VAL B C 1 ATOM 4108 O O . VAL B 1 25 ? -14.044 -6.241 27.784 1.00 23.93 ? 25 VAL B O 1 ATOM 4109 C CB . VAL B 1 25 ? -14.457 -9.339 27.359 1.00 24.40 ? 25 VAL B CB 1 ATOM 4110 C CG1 . VAL B 1 25 ? -15.905 -9.375 27.876 1.00 25.42 ? 25 VAL B CG1 1 ATOM 4111 C CG2 . VAL B 1 25 ? -14.109 -10.676 26.678 1.00 24.77 ? 25 VAL B CG2 1 ATOM 4112 N N . LEU B 1 26 ? -15.716 -6.264 26.278 1.00 23.52 ? 26 LEU B N 1 ATOM 4113 C CA . LEU B 1 26 ? -16.271 -4.984 26.653 1.00 24.31 ? 26 LEU B CA 1 ATOM 4114 C C . LEU B 1 26 ? -17.366 -5.176 27.712 1.00 25.07 ? 26 LEU B C 1 ATOM 4115 O O . LEU B 1 26 ? -18.205 -6.049 27.574 1.00 25.28 ? 26 LEU B O 1 ATOM 4116 C CB . LEU B 1 26 ? -16.873 -4.313 25.412 1.00 23.93 ? 26 LEU B CB 1 ATOM 4117 C CG . LEU B 1 26 ? -16.075 -3.242 24.653 1.00 24.47 ? 26 LEU B CG 1 ATOM 4118 C CD1 . LEU B 1 26 ? -14.570 -3.501 24.580 1.00 24.29 ? 26 LEU B CD1 1 ATOM 4119 C CD2 . LEU B 1 26 ? -16.704 -2.856 23.284 1.00 22.39 ? 26 LEU B CD2 1 ATOM 4120 N N . ASN B 1 27 ? -17.366 -4.350 28.748 1.00 25.76 ? 27 ASN B N 1 ATOM 4121 C CA . ASN B 1 27 ? -18.497 -4.314 29.669 1.00 26.69 ? 27 ASN B CA 1 ATOM 4122 C C . ASN B 1 27 ? -19.654 -3.495 29.083 1.00 27.01 ? 27 ASN B C 1 ATOM 4123 O O . ASN B 1 27 ? -19.528 -2.889 28.010 1.00 25.48 ? 27 ASN B O 1 ATOM 4124 C CB . ASN B 1 27 ? -18.074 -3.774 31.043 1.00 27.05 ? 27 ASN B CB 1 ATOM 4125 C CG . ASN B 1 27 ? -17.536 -2.350 30.992 1.00 26.91 ? 27 ASN B CG 1 ATOM 4126 O OD1 . ASN B 1 27 ? -18.142 -1.440 30.415 1.00 28.63 ? 27 ASN B OD1 1 ATOM 4127 N ND2 . ASN B 1 27 ? -16.402 -2.145 31.646 1.00 28.17 ? 27 ASN B ND2 1 ATOM 4128 N N . THR B 1 28 ? -20.780 -3.446 29.792 1.00 27.21 ? 28 THR B N 1 ATOM 4129 C CA . THR B 1 28 ? -21.997 -2.912 29.171 1.00 27.33 ? 28 THR B CA 1 ATOM 4130 C C . THR B 1 28 ? -21.901 -1.404 28.877 1.00 26.85 ? 28 THR B C 1 ATOM 4131 O O . THR B 1 28 ? -22.438 -0.926 27.869 1.00 26.93 ? 28 THR B O 1 ATOM 4132 C CB . THR B 1 28 ? -23.300 -3.270 29.978 1.00 27.67 ? 28 THR B CB 1 ATOM 4133 O OG1 . THR B 1 28 ? -23.400 -2.424 31.116 1.00 30.56 ? 28 THR B OG1 1 ATOM 4134 C CG2 . THR B 1 28 ? -23.266 -4.682 30.457 1.00 27.96 ? 28 THR B CG2 1 ATOM 4135 N N . LYS B 1 29 ? -21.206 -0.662 29.738 1.00 25.75 ? 29 LYS B N 1 ATOM 4136 C CA . LYS B 1 29 ? -20.971 0.768 29.510 1.00 25.36 ? 29 LYS B CA 1 ATOM 4137 C C . LYS B 1 29 ? -20.075 1.012 28.254 1.00 24.32 ? 29 LYS B C 1 ATOM 4138 O O . LYS B 1 29 ? -20.313 1.949 27.480 1.00 23.48 ? 29 LYS B O 1 ATOM 4139 C CB . LYS B 1 29 ? -20.323 1.394 30.745 1.00 25.80 ? 29 LYS B CB 1 ATOM 4140 C CG . LYS B 1 29 ? -20.670 2.856 30.977 1.00 30.71 ? 29 LYS B CG 1 ATOM 4141 C CD . LYS B 1 29 ? -21.511 3.041 32.253 1.00 35.79 ? 29 LYS B CD 1 ATOM 4142 C CE . LYS B 1 29 ? -20.635 3.464 33.439 1.00 39.77 ? 29 LYS B CE 1 ATOM 4143 N NZ . LYS B 1 29 ? -21.377 3.547 34.750 1.00 41.94 ? 29 LYS B NZ 1 ATOM 4144 N N . GLU B 1 30 ? -19.057 0.166 28.086 1.00 23.65 ? 30 GLU B N 1 ATOM 4145 C CA . GLU B 1 30 ? -18.175 0.166 26.902 1.00 23.86 ? 30 GLU B CA 1 ATOM 4146 C C . GLU B 1 30 ? -18.922 -0.269 25.634 1.00 24.06 ? 30 GLU B C 1 ATOM 4147 O O . GLU B 1 30 ? -18.682 0.286 24.557 1.00 24.21 ? 30 GLU B O 1 ATOM 4148 C CB . GLU B 1 30 ? -16.961 -0.747 27.125 1.00 23.24 ? 30 GLU B CB 1 ATOM 4149 C CG . GLU B 1 30 ? -15.945 -0.230 28.152 1.00 22.51 ? 30 GLU B CG 1 ATOM 4150 C CD . GLU B 1 30 ? -14.907 -1.279 28.541 1.00 23.94 ? 30 GLU B CD 1 ATOM 4151 O OE1 . GLU B 1 30 ? -15.256 -2.462 28.647 1.00 25.56 ? 30 GLU B OE1 1 ATOM 4152 O OE2 . GLU B 1 30 ? -13.707 -0.930 28.716 1.00 25.59 ? 30 GLU B OE2 1 ATOM 4153 N N . GLU B 1 31 ? -19.833 -1.239 25.753 1.00 23.93 ? 31 GLU B N 1 ATOM 4154 C CA . GLU B 1 31 ? -20.685 -1.601 24.592 1.00 24.71 ? 31 GLU B CA 1 ATOM 4155 C C . GLU B 1 31 ? -21.499 -0.406 24.083 1.00 24.15 ? 31 GLU B C 1 ATOM 4156 O O . GLU B 1 31 ? -21.592 -0.183 22.878 1.00 23.90 ? 31 GLU B O 1 ATOM 4157 C CB . GLU B 1 31 ? -21.594 -2.794 24.886 1.00 25.62 ? 31 GLU B CB 1 ATOM 4158 C CG . GLU B 1 31 ? -20.884 -4.133 24.989 1.00 26.77 ? 31 GLU B CG 1 ATOM 4159 C CD . GLU B 1 31 ? -20.489 -4.749 23.629 1.00 32.96 ? 31 GLU B CD 1 ATOM 4160 O OE1 . GLU B 1 31 ? -20.748 -4.151 22.547 1.00 34.52 ? 31 GLU B OE1 1 ATOM 4161 O OE2 . GLU B 1 31 ? -19.909 -5.858 23.648 1.00 33.09 ? 31 GLU B OE2 1 ATOM 4162 N N . LEU B 1 32 ? -22.071 0.358 25.011 1.00 23.86 ? 32 LEU B N 1 ATOM 4163 C CA . LEU B 1 32 ? -22.815 1.572 24.686 1.00 23.97 ? 32 LEU B CA 1 ATOM 4164 C C . LEU B 1 32 ? -21.920 2.647 24.046 1.00 23.10 ? 32 LEU B C 1 ATOM 4165 O O . LEU B 1 32 ? -22.309 3.271 23.037 1.00 22.75 ? 32 LEU B O 1 ATOM 4166 C CB . LEU B 1 32 ? -23.462 2.127 25.957 1.00 24.40 ? 32 LEU B CB 1 ATOM 4167 C CG . LEU B 1 32 ? -24.743 2.938 25.874 1.00 28.70 ? 32 LEU B CG 1 ATOM 4168 C CD1 . LEU B 1 32 ? -24.510 4.327 25.252 1.00 29.64 ? 32 LEU B CD1 1 ATOM 4169 C CD2 . LEU B 1 32 ? -25.825 2.162 25.110 1.00 30.83 ? 32 LEU B CD2 1 ATOM 4170 N N . ALA B 1 33 ? -20.751 2.895 24.658 1.00 22.04 ? 33 ALA B N 1 ATOM 4171 C CA . ALA B 1 33 ? -19.761 3.817 24.106 1.00 21.11 ? 33 ALA B CA 1 ATOM 4172 C C . ALA B 1 33 ? -19.357 3.415 22.666 1.00 20.99 ? 33 ALA B C 1 ATOM 4173 O O . ALA B 1 33 ? -19.304 4.262 21.794 1.00 20.70 ? 33 ALA B O 1 ATOM 4174 C CB . ALA B 1 33 ? -18.533 3.917 25.016 1.00 21.23 ? 33 ALA B CB 1 ATOM 4175 N N . ASN B 1 34 ? -19.104 2.128 22.440 1.00 20.81 ? 34 ASN B N 1 ATOM 4176 C CA . ASN B 1 34 ? -18.758 1.612 21.126 1.00 20.41 ? 34 ASN B CA 1 ATOM 4177 C C . ASN B 1 34 ? -19.889 1.832 20.110 1.00 21.07 ? 34 ASN B C 1 ATOM 4178 O O . ASN B 1 34 ? -19.647 2.230 18.977 1.00 20.64 ? 34 ASN B O 1 ATOM 4179 C CB . ASN B 1 34 ? -18.395 0.121 21.235 1.00 20.53 ? 34 ASN B CB 1 ATOM 4180 C CG . ASN B 1 34 ? -17.937 -0.488 19.889 1.00 20.56 ? 34 ASN B CG 1 ATOM 4181 O OD1 . ASN B 1 34 ? -18.597 -1.362 19.335 1.00 21.52 ? 34 ASN B OD1 1 ATOM 4182 N ND2 . ASN B 1 34 ? -16.857 0.015 19.355 1.00 16.23 ? 34 ASN B ND2 1 ATOM 4183 N N . GLU B 1 35 ? -21.137 1.603 20.530 1.00 21.87 ? 35 GLU B N 1 ATOM 4184 C CA . GLU B 1 35 ? -22.291 1.818 19.651 1.00 22.36 ? 35 GLU B CA 1 ATOM 4185 C C . GLU B 1 35 ? -22.355 3.240 19.173 1.00 20.76 ? 35 GLU B C 1 ATOM 4186 O O . GLU B 1 35 ? -22.627 3.459 18.014 1.00 21.52 ? 35 GLU B O 1 ATOM 4187 C CB . GLU B 1 35 ? -23.635 1.523 20.352 1.00 22.65 ? 35 GLU B CB 1 ATOM 4188 C CG . GLU B 1 35 ? -23.942 0.099 20.512 1.00 28.86 ? 35 GLU B CG 1 ATOM 4189 C CD . GLU B 1 35 ? -25.459 -0.192 20.442 1.00 36.53 ? 35 GLU B CD 1 ATOM 4190 O OE1 . GLU B 1 35 ? -26.283 0.769 20.501 1.00 37.08 ? 35 GLU B OE1 1 ATOM 4191 O OE2 . GLU B 1 35 ? -25.806 -1.390 20.304 1.00 39.67 ? 35 GLU B OE2 1 ATOM 4192 N N . ARG B 1 36 ? -22.141 4.197 20.070 1.00 20.30 ? 36 ARG B N 1 ATOM 4193 C CA . ARG B 1 36 ? -22.195 5.623 19.722 1.00 20.16 ? 36 ARG B CA 1 ATOM 4194 C C . ARG B 1 36 ? -21.008 6.056 18.845 1.00 19.32 ? 36 ARG B C 1 ATOM 4195 O O . ARG B 1 36 ? -21.167 6.737 17.842 1.00 17.68 ? 36 ARG B O 1 ATOM 4196 C CB . ARG B 1 36 ? -22.271 6.507 20.986 1.00 20.78 ? 36 ARG B CB 1 ATOM 4197 C CG . ARG B 1 36 ? -23.438 6.145 21.954 1.00 25.05 ? 36 ARG B CG 1 ATOM 4198 C CD . ARG B 1 36 ? -23.595 7.210 23.044 1.00 30.87 ? 36 ARG B CD 1 ATOM 4199 N NE . ARG B 1 36 ? -24.754 8.059 22.778 1.00 36.78 ? 36 ARG B NE 1 ATOM 4200 C CZ . ARG B 1 36 ? -24.847 9.353 23.080 1.00 39.72 ? 36 ARG B CZ 1 ATOM 4201 N NH1 . ARG B 1 36 ? -23.833 9.993 23.659 1.00 40.88 ? 36 ARG B NH1 1 ATOM 4202 N NH2 . ARG B 1 36 ? -25.961 10.019 22.783 1.00 41.35 ? 36 ARG B NH2 1 ATOM 4203 N N . LEU B 1 37 ? -19.802 5.677 19.246 1.00 19.14 ? 37 LEU B N 1 ATOM 4204 C CA . LEU B 1 37 ? -18.631 5.959 18.422 1.00 18.27 ? 37 LEU B CA 1 ATOM 4205 C C . LEU B 1 37 ? -18.752 5.346 17.003 1.00 17.70 ? 37 LEU B C 1 ATOM 4206 O O . LEU B 1 37 ? -18.497 6.029 16.003 1.00 16.76 ? 37 LEU B O 1 ATOM 4207 C CB . LEU B 1 37 ? -17.377 5.462 19.151 1.00 18.21 ? 37 LEU B CB 1 ATOM 4208 C CG . LEU B 1 37 ? -16.053 5.402 18.379 1.00 18.81 ? 37 LEU B CG 1 ATOM 4209 C CD1 . LEU B 1 37 ? -15.534 6.810 18.074 1.00 17.04 ? 37 LEU B CD1 1 ATOM 4210 C CD2 . LEU B 1 37 ? -15.051 4.585 19.194 1.00 18.70 ? 37 LEU B CD2 1 ATOM 4211 N N . MET B 1 38 ? -19.130 4.073 16.912 1.00 18.29 ? 38 MET B N 1 ATOM 4212 C CA . MET B 1 38 ? -19.250 3.417 15.603 1.00 18.91 ? 38 MET B CA 1 ATOM 4213 C C . MET B 1 38 ? -20.360 4.025 14.727 1.00 19.70 ? 38 MET B C 1 ATOM 4214 O O . MET B 1 38 ? -20.223 4.121 13.502 1.00 19.84 ? 38 MET B O 1 ATOM 4215 C CB . MET B 1 38 ? -19.432 1.902 15.747 1.00 19.44 ? 38 MET B CB 1 ATOM 4216 C CG . MET B 1 38 ? -18.207 1.194 16.326 1.00 17.46 ? 38 MET B CG 1 ATOM 4217 S SD . MET B 1 38 ? -16.653 1.574 15.458 1.00 20.24 ? 38 MET B SD 1 ATOM 4218 C CE . MET B 1 38 ? -16.935 0.690 13.917 1.00 13.31 ? 38 MET B CE 1 ATOM 4219 N N . THR B 1 39 ? -21.451 4.466 15.355 1.00 20.49 ? 39 THR B N 1 ATOM 4220 C CA . THR B 1 39 ? -22.490 5.188 14.631 1.00 20.25 ? 39 THR B CA 1 ATOM 4221 C C . THR B 1 39 ? -21.912 6.438 13.955 1.00 19.86 ? 39 THR B C 1 ATOM 4222 O O . THR B 1 39 ? -22.175 6.686 12.778 1.00 19.39 ? 39 THR B O 1 ATOM 4223 C CB . THR B 1 39 ? -23.673 5.565 15.562 1.00 20.70 ? 39 THR B CB 1 ATOM 4224 O OG1 . THR B 1 39 ? -24.285 4.371 16.061 1.00 23.07 ? 39 THR B OG1 1 ATOM 4225 C CG2 . THR B 1 39 ? -24.712 6.387 14.830 1.00 22.49 ? 39 THR B CG2 1 ATOM 4226 N N . LEU B 1 40 ? -21.133 7.228 14.686 1.00 19.61 ? 40 LEU B N 1 ATOM 4227 C CA . LEU B 1 40 ? -20.577 8.468 14.097 1.00 20.52 ? 40 LEU B CA 1 ATOM 4228 C C . LEU B 1 40 ? -19.520 8.151 13.031 1.00 20.11 ? 40 LEU B C 1 ATOM 4229 O O . LEU B 1 40 ? -19.460 8.796 11.975 1.00 19.32 ? 40 LEU B O 1 ATOM 4230 C CB . LEU B 1 40 ? -19.972 9.346 15.184 1.00 21.07 ? 40 LEU B CB 1 ATOM 4231 C CG . LEU B 1 40 ? -21.001 9.877 16.170 1.00 22.47 ? 40 LEU B CG 1 ATOM 4232 C CD1 . LEU B 1 40 ? -20.302 10.228 17.479 1.00 24.25 ? 40 LEU B CD1 1 ATOM 4233 C CD2 . LEU B 1 40 ? -21.728 11.092 15.570 1.00 23.17 ? 40 LEU B CD2 1 ATOM 4234 N N . LYS B 1 41 ? -18.699 7.143 13.320 1.00 19.67 ? 41 LYS B N 1 ATOM 4235 C CA . LYS B 1 41 ? -17.692 6.679 12.374 1.00 19.70 ? 41 LYS B CA 1 ATOM 4236 C C . LYS B 1 41 ? -18.341 6.186 11.067 1.00 20.28 ? 41 LYS B C 1 ATOM 4237 O O . LYS B 1 41 ? -17.890 6.530 9.991 1.00 19.66 ? 41 LYS B O 1 ATOM 4238 C CB . LYS B 1 41 ? -16.849 5.561 12.990 1.00 18.62 ? 41 LYS B CB 1 ATOM 4239 C CG . LYS B 1 41 ? -15.988 4.838 11.958 1.00 19.37 ? 41 LYS B CG 1 ATOM 4240 C CD . LYS B 1 41 ? -14.992 3.881 12.607 1.00 15.78 ? 41 LYS B CD 1 ATOM 4241 C CE . LYS B 1 41 ? -14.280 3.098 11.497 1.00 18.80 ? 41 LYS B CE 1 ATOM 4242 N NZ . LYS B 1 41 ? -13.105 2.329 12.010 1.00 16.21 ? 41 LYS B NZ 1 ATOM 4243 N N . ILE B 1 42 ? -19.378 5.361 11.178 1.00 20.73 ? 42 ILE B N 1 ATOM 4244 C CA . ILE B 1 42 ? -20.071 4.853 9.986 1.00 22.06 ? 42 ILE B CA 1 ATOM 4245 C C . ILE B 1 42 ? -20.693 5.979 9.166 1.00 21.91 ? 42 ILE B C 1 ATOM 4246 O O . ILE B 1 42 ? -20.539 5.988 7.939 1.00 22.68 ? 42 ILE B O 1 ATOM 4247 C CB . ILE B 1 42 ? -21.049 3.720 10.331 1.00 21.84 ? 42 ILE B CB 1 ATOM 4248 C CG1 . ILE B 1 42 ? -20.249 2.521 10.844 1.00 23.84 ? 42 ILE B CG1 1 ATOM 4249 C CG2 . ILE B 1 42 ? -21.898 3.293 9.104 1.00 24.24 ? 42 ILE B CG2 1 ATOM 4250 C CD1 . ILE B 1 42 ? -21.105 1.467 11.586 1.00 29.17 ? 42 ILE B CD1 1 ATOM 4251 N N . ALA B 1 43 ? -21.350 6.933 9.836 1.00 21.19 ? 43 ALA B N 1 ATOM 4252 C CA . ALA B 1 43 ? -21.870 8.156 9.194 1.00 20.93 ? 43 ALA B CA 1 ATOM 4253 C C . ALA B 1 43 ? -20.794 8.979 8.462 1.00 21.13 ? 43 ALA B C 1 ATOM 4254 O O . ALA B 1 43 ? -21.016 9.448 7.339 1.00 21.02 ? 43 ALA B O 1 ATOM 4255 C CB . ALA B 1 43 ? -22.587 9.044 10.238 1.00 20.43 ? 43 ALA B CB 1 ATOM 4256 N N . GLU B 1 44 ? -19.629 9.175 9.089 1.00 20.90 ? 44 GLU B N 1 ATOM 4257 C CA . GLU B 1 44 ? -18.553 9.922 8.431 1.00 21.76 ? 44 GLU B CA 1 ATOM 4258 C C . GLU B 1 44 ? -18.045 9.142 7.187 1.00 22.06 ? 44 GLU B C 1 ATOM 4259 O O . GLU B 1 44 ? -17.826 9.724 6.116 1.00 22.19 ? 44 GLU B O 1 ATOM 4260 C CB . GLU B 1 44 ? -17.422 10.243 9.431 1.00 21.87 ? 44 GLU B CB 1 ATOM 4261 C CG . GLU B 1 44 ? -16.071 10.579 8.788 1.00 24.95 ? 44 GLU B CG 1 ATOM 4262 C CD . GLU B 1 44 ? -15.086 11.319 9.729 1.00 30.29 ? 44 GLU B CD 1 ATOM 4263 O OE1 . GLU B 1 44 ? -15.445 11.527 10.932 1.00 29.52 ? 44 GLU B OE1 1 ATOM 4264 O OE2 . GLU B 1 44 ? -13.956 11.665 9.251 1.00 27.29 ? 44 GLU B OE2 1 ATOM 4265 N N . MET B 1 45 ? -17.862 7.836 7.327 1.00 22.48 ? 45 MET B N 1 ATOM 4266 C CA . MET B 1 45 ? -17.391 7.023 6.202 1.00 25.39 ? 45 MET B CA 1 ATOM 4267 C C . MET B 1 45 ? -18.386 6.965 5.024 1.00 25.40 ? 45 MET B C 1 ATOM 4268 O O . MET B 1 45 ? -17.978 7.032 3.850 1.00 25.75 ? 45 MET B O 1 ATOM 4269 C CB . MET B 1 45 ? -16.960 5.618 6.686 1.00 26.90 ? 45 MET B CB 1 ATOM 4270 C CG . MET B 1 45 ? -15.525 5.631 7.237 1.00 30.76 ? 45 MET B CG 1 ATOM 4271 S SD . MET B 1 45 ? -14.890 4.072 7.920 1.00 44.34 ? 45 MET B SD 1 ATOM 4272 C CE . MET B 1 45 ? -14.397 3.313 6.374 1.00 39.81 ? 45 MET B CE 1 ATOM 4273 N N . LYS B 1 46 ? -19.679 6.869 5.333 1.00 25.69 ? 46 LYS B N 1 ATOM 4274 C CA . LYS B 1 46 ? -20.745 6.859 4.308 1.00 26.34 ? 46 LYS B CA 1 ATOM 4275 C C . LYS B 1 46 ? -20.708 8.113 3.482 1.00 25.41 ? 46 LYS B C 1 ATOM 4276 O O . LYS B 1 46 ? -20.840 8.065 2.246 1.00 25.01 ? 46 LYS B O 1 ATOM 4277 C CB . LYS B 1 46 ? -22.131 6.762 4.945 1.00 27.59 ? 46 LYS B CB 1 ATOM 4278 C CG . LYS B 1 46 ? -22.793 5.371 4.895 1.00 33.12 ? 46 LYS B CG 1 ATOM 4279 C CD . LYS B 1 46 ? -21.826 4.217 5.210 1.00 37.29 ? 46 LYS B CD 1 ATOM 4280 C CE . LYS B 1 46 ? -22.537 2.869 5.016 1.00 40.41 ? 46 LYS B CE 1 ATOM 4281 N NZ . LYS B 1 46 ? -21.588 1.712 5.134 1.00 42.75 ? 46 LYS B NZ 1 ATOM 4282 N N . GLU B 1 47 ? -20.547 9.241 4.168 1.00 24.13 ? 47 GLU B N 1 ATOM 4283 C CA . GLU B 1 47 ? -20.413 10.520 3.497 1.00 23.42 ? 47 GLU B CA 1 ATOM 4284 C C . GLU B 1 47 ? -19.144 10.602 2.621 1.00 23.07 ? 47 GLU B C 1 ATOM 4285 O O . GLU B 1 47 ? -19.215 11.028 1.457 1.00 23.22 ? 47 GLU B O 1 ATOM 4286 C CB . GLU B 1 47 ? -20.481 11.670 4.501 1.00 23.34 ? 47 GLU B CB 1 ATOM 4287 C CG . GLU B 1 47 ? -20.281 13.082 3.912 1.00 25.48 ? 47 GLU B CG 1 ATOM 4288 C CD . GLU B 1 47 ? -21.316 13.515 2.860 1.00 29.01 ? 47 GLU B CD 1 ATOM 4289 O OE1 . GLU B 1 47 ? -22.413 12.918 2.750 1.00 27.68 ? 47 GLU B OE1 1 ATOM 4290 O OE2 . GLU B 1 47 ? -21.010 14.492 2.130 1.00 31.56 ? 47 GLU B OE2 1 ATOM 4291 N N . ALA B 1 48 ? -18.000 10.215 3.183 1.00 21.76 ? 48 ALA B N 1 ATOM 4292 C CA . ALA B 1 48 ? -16.751 10.122 2.441 1.00 21.64 ? 48 ALA B CA 1 ATOM 4293 C C . ALA B 1 48 ? -16.899 9.262 1.187 1.00 22.05 ? 48 ALA B C 1 ATOM 4294 O O . ALA B 1 48 ? -16.392 9.637 0.145 1.00 22.35 ? 48 ALA B O 1 ATOM 4295 C CB . ALA B 1 48 ? -15.618 9.564 3.345 1.00 22.03 ? 48 ALA B CB 1 ATOM 4296 N N . MET B 1 49 ? -17.606 8.133 1.288 1.00 22.25 ? 49 MET B N 1 ATOM 4297 C CA . MET B 1 49 ? -17.816 7.241 0.145 1.00 23.59 ? 49 MET B CA 1 ATOM 4298 C C . MET B 1 49 ? -18.655 7.911 -0.934 1.00 24.11 ? 49 MET B C 1 ATOM 4299 O O . MET B 1 49 ? -18.428 7.657 -2.107 1.00 24.27 ? 49 MET B O 1 ATOM 4300 C CB . MET B 1 49 ? -18.429 5.874 0.565 1.00 23.52 ? 49 MET B CB 1 ATOM 4301 C CG . MET B 1 49 ? -17.517 5.042 1.474 1.00 24.32 ? 49 MET B CG 1 ATOM 4302 S SD . MET B 1 49 ? -18.184 3.510 2.183 1.00 27.33 ? 49 MET B SD 1 ATOM 4303 C CE . MET B 1 49 ? -17.998 2.393 0.795 1.00 25.91 ? 49 MET B CE 1 ATOM 4304 N N . ARG B 1 50 ? -19.605 8.767 -0.530 1.00 24.41 ? 50 ARG B N 1 ATOM 4305 C CA . ARG B 1 50 ? -20.433 9.541 -1.477 1.00 24.87 ? 50 ARG B CA 1 ATOM 4306 C C . ARG B 1 50 ? -19.641 10.604 -2.236 1.00 24.52 ? 50 ARG B C 1 ATOM 4307 O O . ARG B 1 50 ? -19.822 10.755 -3.438 1.00 25.19 ? 50 ARG B O 1 ATOM 4308 C CB . ARG B 1 50 ? -21.613 10.225 -0.752 1.00 24.79 ? 50 ARG B CB 1 ATOM 4309 C CG . ARG B 1 50 ? -22.566 11.040 -1.674 1.00 27.06 ? 50 ARG B CG 1 ATOM 4310 C CD . ARG B 1 50 ? -23.741 11.639 -0.863 1.00 28.84 ? 50 ARG B CD 1 ATOM 4311 N NE . ARG B 1 50 ? -23.355 12.835 -0.109 1.00 27.10 ? 50 ARG B NE 1 ATOM 4312 C CZ . ARG B 1 50 ? -23.175 14.038 -0.648 1.00 29.76 ? 50 ARG B CZ 1 ATOM 4313 N NH1 . ARG B 1 50 ? -23.333 14.229 -1.955 1.00 30.42 ? 50 ARG B NH1 1 ATOM 4314 N NH2 . ARG B 1 50 ? -22.829 15.062 0.118 1.00 32.07 ? 50 ARG B NH2 1 ATOM 4315 N N . THR B 1 51 ? -18.772 11.343 -1.542 1.00 23.57 ? 51 THR B N 1 ATOM 4316 C CA . THR B 1 51 ? -18.082 12.504 -2.148 1.00 22.71 ? 51 THR B CA 1 ATOM 4317 C C . THR B 1 51 ? -16.632 12.212 -2.523 1.00 22.08 ? 51 THR B C 1 ATOM 4318 O O . THR B 1 51 ? -16.025 12.934 -3.301 1.00 21.46 ? 51 THR B O 1 ATOM 4319 C CB . THR B 1 51 ? -18.089 13.724 -1.199 1.00 23.04 ? 51 THR B CB 1 ATOM 4320 O OG1 . THR B 1 51 ? -17.367 13.404 0.001 1.00 20.92 ? 51 THR B OG1 1 ATOM 4321 C CG2 . THR B 1 51 ? -19.537 14.131 -0.839 1.00 23.04 ? 51 THR B CG2 1 ATOM 4322 N N . LEU B 1 52 ? -16.090 11.129 -1.969 1.00 21.27 ? 52 LEU B N 1 ATOM 4323 C CA . LEU B 1 52 ? -14.662 10.822 -2.059 1.00 21.05 ? 52 LEU B CA 1 ATOM 4324 C C . LEU B 1 52 ? -13.780 11.830 -1.331 1.00 21.45 ? 52 LEU B C 1 ATOM 4325 O O . LEU B 1 52 ? -12.567 11.812 -1.503 1.00 22.60 ? 52 LEU B O 1 ATOM 4326 C CB . LEU B 1 52 ? -14.182 10.604 -3.495 1.00 21.03 ? 52 LEU B CB 1 ATOM 4327 C CG . LEU B 1 52 ? -14.900 9.533 -4.311 1.00 21.62 ? 52 LEU B CG 1 ATOM 4328 C CD1 . LEU B 1 52 ? -14.240 9.378 -5.703 1.00 21.38 ? 52 LEU B CD1 1 ATOM 4329 C CD2 . LEU B 1 52 ? -14.911 8.220 -3.541 1.00 22.18 ? 52 LEU B CD2 1 ATOM 4330 N N . ILE B 1 53 ? -14.371 12.679 -0.488 1.00 20.35 ? 53 ILE B N 1 ATOM 4331 C CA . ILE B 1 53 ? -13.569 13.540 0.389 1.00 19.97 ? 53 ILE B CA 1 ATOM 4332 C C . ILE B 1 53 ? -13.345 12.762 1.677 1.00 19.44 ? 53 ILE B C 1 ATOM 4333 O O . ILE B 1 53 ? -14.216 12.702 2.530 1.00 20.15 ? 53 ILE B O 1 ATOM 4334 C CB . ILE B 1 53 ? -14.250 14.910 0.647 1.00 19.80 ? 53 ILE B CB 1 ATOM 4335 C CG1 . ILE B 1 53 ? -14.479 15.631 -0.691 1.00 21.46 ? 53 ILE B CG1 1 ATOM 4336 C CG2 . ILE B 1 53 ? -13.371 15.808 1.547 1.00 19.44 ? 53 ILE B CG2 1 ATOM 4337 C CD1 . ILE B 1 53 ? -15.355 16.912 -0.577 1.00 24.06 ? 53 ILE B CD1 1 ATOM 4338 N N . PHE B 1 54 ? -12.185 12.123 1.776 1.00 17.98 ? 54 PHE B N 1 ATOM 4339 C CA . PHE B 1 54 ? -11.890 11.196 2.839 1.00 17.39 ? 54 PHE B CA 1 ATOM 4340 C C . PHE B 1 54 ? -10.497 11.544 3.348 1.00 16.82 ? 54 PHE B C 1 ATOM 4341 O O . PHE B 1 54 ? -9.504 11.330 2.635 1.00 16.58 ? 54 PHE B O 1 ATOM 4342 C CB . PHE B 1 54 ? -11.940 9.756 2.315 1.00 17.55 ? 54 PHE B CB 1 ATOM 4343 C CG . PHE B 1 54 ? -11.749 8.716 3.397 1.00 18.46 ? 54 PHE B CG 1 ATOM 4344 C CD1 . PHE B 1 54 ? -12.557 8.720 4.523 1.00 18.37 ? 54 PHE B CD1 1 ATOM 4345 C CD2 . PHE B 1 54 ? -10.751 7.759 3.300 1.00 16.46 ? 54 PHE B CD2 1 ATOM 4346 C CE1 . PHE B 1 54 ? -12.396 7.767 5.535 1.00 18.96 ? 54 PHE B CE1 1 ATOM 4347 C CE2 . PHE B 1 54 ? -10.571 6.817 4.320 1.00 17.83 ? 54 PHE B CE2 1 ATOM 4348 C CZ . PHE B 1 54 ? -11.417 6.810 5.421 1.00 18.36 ? 54 PHE B CZ 1 ATOM 4349 N N . PRO B 1 55 ? -10.423 12.151 4.547 1.00 15.60 ? 55 PRO B N 1 ATOM 4350 C CA . PRO B 1 55 ? -9.158 12.720 4.986 1.00 14.93 ? 55 PRO B CA 1 ATOM 4351 C C . PRO B 1 55 ? -7.949 11.784 4.973 1.00 14.07 ? 55 PRO B C 1 ATOM 4352 O O . PRO B 1 55 ? -6.906 12.235 4.549 1.00 15.30 ? 55 PRO B O 1 ATOM 4353 C CB . PRO B 1 55 ? -9.469 13.238 6.399 1.00 14.04 ? 55 PRO B CB 1 ATOM 4354 C CG . PRO B 1 55 ? -10.939 13.577 6.325 1.00 15.92 ? 55 PRO B CG 1 ATOM 4355 C CD . PRO B 1 55 ? -11.537 12.503 5.458 1.00 15.57 ? 55 PRO B CD 1 ATOM 4356 N N . PRO B 1 56 ? -8.068 10.497 5.429 1.00 14.18 ? 56 PRO B N 1 ATOM 4357 C CA . PRO B 1 56 ? -6.847 9.648 5.356 1.00 14.51 ? 56 PRO B CA 1 ATOM 4358 C C . PRO B 1 56 ? -6.336 9.430 3.935 1.00 15.07 ? 56 PRO B C 1 ATOM 4359 O O . PRO B 1 56 ? -5.124 9.215 3.723 1.00 15.70 ? 56 PRO B O 1 ATOM 4360 C CB . PRO B 1 56 ? -7.299 8.296 5.970 1.00 14.51 ? 56 PRO B CB 1 ATOM 4361 C CG . PRO B 1 56 ? -8.412 8.672 6.909 1.00 14.64 ? 56 PRO B CG 1 ATOM 4362 C CD . PRO B 1 56 ? -9.155 9.809 6.152 1.00 12.47 ? 56 PRO B CD 1 ATOM 4363 N N . SER B 1 57 ? -7.241 9.516 2.966 1.00 16.14 ? 57 SER B N 1 ATOM 4364 C CA . SER B 1 57 ? -6.865 9.348 1.565 1.00 17.26 ? 57 SER B CA 1 ATOM 4365 C C . SER B 1 57 ? -6.257 10.606 0.925 1.00 17.33 ? 57 SER B C 1 ATOM 4366 O O . SER B 1 57 ? -5.732 10.535 -0.175 1.00 18.43 ? 57 SER B O 1 ATOM 4367 C CB . SER B 1 57 ? -8.053 8.816 0.747 1.00 17.32 ? 57 SER B CB 1 ATOM 4368 O OG . SER B 1 57 ? -8.935 9.880 0.424 1.00 20.51 ? 57 SER B OG 1 ATOM 4369 N N . MET B 1 58 ? -6.307 11.735 1.628 1.00 16.87 ? 58 MET B N 1 ATOM 4370 C CA . MET B 1 58 ? -5.777 13.005 1.151 1.00 17.10 ? 58 MET B CA 1 ATOM 4371 C C . MET B 1 58 ? -4.485 13.281 1.920 1.00 16.81 ? 58 MET B C 1 ATOM 4372 O O . MET B 1 58 ? -4.255 12.678 2.997 1.00 16.62 ? 58 MET B O 1 ATOM 4373 C CB . MET B 1 58 ? -6.776 14.137 1.470 1.00 17.90 ? 58 MET B CB 1 ATOM 4374 C CG . MET B 1 58 ? -8.169 13.927 0.887 1.00 20.76 ? 58 MET B CG 1 ATOM 4375 S SD . MET B 1 58 ? -9.402 15.050 1.602 1.00 26.48 ? 58 MET B SD 1 ATOM 4376 C CE . MET B 1 58 ? -8.524 16.627 1.442 1.00 25.09 ? 58 MET B CE 1 ATOM 4377 N N . HIS B 1 59 ? -3.662 14.185 1.400 1.00 16.17 ? 59 HIS B N 1 ATOM 4378 C CA . HIS B 1 59 ? -2.427 14.575 2.094 1.00 17.13 ? 59 HIS B CA 1 ATOM 4379 C C . HIS B 1 59 ? -2.799 15.294 3.398 1.00 17.70 ? 59 HIS B C 1 ATOM 4380 O O . HIS B 1 59 ? -3.684 16.175 3.415 1.00 16.72 ? 59 HIS B O 1 ATOM 4381 C CB . HIS B 1 59 ? -1.551 15.456 1.210 1.00 16.04 ? 59 HIS B CB 1 ATOM 4382 C CG . HIS B 1 59 ? -0.153 15.652 1.720 1.00 15.58 ? 59 HIS B CG 1 ATOM 4383 N ND1 . HIS B 1 59 ? 0.141 16.387 2.851 1.00 13.55 ? 59 HIS B ND1 1 ATOM 4384 C CD2 . HIS B 1 59 ? 1.037 15.232 1.227 1.00 13.08 ? 59 HIS B CD2 1 ATOM 4385 C CE1 . HIS B 1 59 ? 1.449 16.412 3.031 1.00 13.35 ? 59 HIS B CE1 1 ATOM 4386 N NE2 . HIS B 1 59 ? 2.017 15.709 2.066 1.00 14.63 ? 59 HIS B NE2 1 ATOM 4387 N N . PHE B 1 60 ? -2.115 14.923 4.475 1.00 17.45 ? 60 PHE B N 1 ATOM 4388 C CA . PHE B 1 60 ? -2.406 15.516 5.784 1.00 17.41 ? 60 PHE B CA 1 ATOM 4389 C C . PHE B 1 60 ? -2.411 17.065 5.789 1.00 17.66 ? 60 PHE B C 1 ATOM 4390 O O . PHE B 1 60 ? -3.223 17.678 6.493 1.00 17.27 ? 60 PHE B O 1 ATOM 4391 C CB . PHE B 1 60 ? -1.473 14.949 6.866 1.00 17.16 ? 60 PHE B CB 1 ATOM 4392 C CG . PHE B 1 60 ? -1.754 15.489 8.242 1.00 16.19 ? 60 PHE B CG 1 ATOM 4393 C CD1 . PHE B 1 60 ? -2.868 15.073 8.953 1.00 14.42 ? 60 PHE B CD1 1 ATOM 4394 C CD2 . PHE B 1 60 ? -0.905 16.416 8.810 1.00 14.00 ? 60 PHE B CD2 1 ATOM 4395 C CE1 . PHE B 1 60 ? -3.127 15.586 10.230 1.00 17.31 ? 60 PHE B CE1 1 ATOM 4396 C CE2 . PHE B 1 60 ? -1.149 16.935 10.110 1.00 14.17 ? 60 PHE B CE2 1 ATOM 4397 C CZ . PHE B 1 60 ? -2.269 16.509 10.804 1.00 17.99 ? 60 PHE B CZ 1 ATOM 4398 N N . PHE B 1 61 ? -1.545 17.699 5.002 1.00 17.92 ? 61 PHE B N 1 ATOM 4399 C CA . PHE B 1 61 ? -1.555 19.173 4.962 1.00 18.21 ? 61 PHE B CA 1 ATOM 4400 C C . PHE B 1 61 ? -2.940 19.686 4.568 1.00 18.85 ? 61 PHE B C 1 ATOM 4401 O O . PHE B 1 61 ? -3.449 20.633 5.187 1.00 19.78 ? 61 PHE B O 1 ATOM 4402 C CB . PHE B 1 61 ? -0.467 19.771 4.044 1.00 18.14 ? 61 PHE B CB 1 ATOM 4403 C CG . PHE B 1 61 ? 0.962 19.421 4.446 1.00 18.52 ? 61 PHE B CG 1 ATOM 4404 C CD1 . PHE B 1 61 ? 1.255 18.920 5.727 1.00 18.11 ? 61 PHE B CD1 1 ATOM 4405 C CD2 . PHE B 1 61 ? 2.000 19.590 3.544 1.00 18.95 ? 61 PHE B CD2 1 ATOM 4406 C CE1 . PHE B 1 61 ? 2.553 18.605 6.080 1.00 17.46 ? 61 PHE B CE1 1 ATOM 4407 C CE2 . PHE B 1 61 ? 3.330 19.250 3.892 1.00 19.23 ? 61 PHE B CE2 1 ATOM 4408 C CZ . PHE B 1 61 ? 3.592 18.759 5.162 1.00 17.90 ? 61 PHE B CZ 1 ATOM 4409 N N . GLN B 1 62 ? -3.564 19.032 3.589 1.00 18.29 ? 62 GLN B N 1 ATOM 4410 C CA . GLN B 1 62 ? -4.906 19.405 3.125 1.00 19.34 ? 62 GLN B CA 1 ATOM 4411 C C . GLN B 1 62 ? -6.048 18.753 3.889 1.00 19.61 ? 62 GLN B C 1 ATOM 4412 O O . GLN B 1 62 ? -7.182 19.242 3.860 1.00 21.31 ? 62 GLN B O 1 ATOM 4413 C CB . GLN B 1 62 ? -5.029 19.173 1.596 1.00 19.34 ? 62 GLN B CB 1 ATOM 4414 C CG . GLN B 1 62 ? -4.281 20.263 0.749 1.00 20.40 ? 62 GLN B CG 1 ATOM 4415 C CD . GLN B 1 62 ? -2.761 20.314 1.010 1.00 21.22 ? 62 GLN B CD 1 ATOM 4416 O OE1 . GLN B 1 62 ? -2.236 21.316 1.497 1.00 23.41 ? 62 GLN B OE1 1 ATOM 4417 N NE2 . GLN B 1 62 ? -2.061 19.218 0.706 1.00 17.34 ? 62 GLN B NE2 1 ATOM 4418 N N . ALA B 1 63 ? -5.754 17.656 4.581 1.00 18.91 ? 63 ALA B N 1 ATOM 4419 C CA . ALA B 1 63 ? -6.757 16.890 5.315 1.00 19.19 ? 63 ALA B CA 1 ATOM 4420 C C . ALA B 1 63 ? -7.060 17.441 6.719 1.00 18.27 ? 63 ALA B C 1 ATOM 4421 O O . ALA B 1 63 ? -8.179 17.269 7.212 1.00 18.25 ? 63 ALA B O 1 ATOM 4422 C CB . ALA B 1 63 ? -6.301 15.418 5.430 1.00 18.45 ? 63 ALA B CB 1 ATOM 4423 N N . LYS B 1 64 ? -6.075 18.080 7.341 1.00 17.75 ? 64 LYS B N 1 ATOM 4424 C CA . LYS B 1 64 ? -6.112 18.415 8.772 1.00 18.97 ? 64 LYS B CA 1 ATOM 4425 C C . LYS B 1 64 ? -7.346 19.233 9.168 1.00 19.58 ? 64 LYS B C 1 ATOM 4426 O O . LYS B 1 64 ? -7.999 18.935 10.168 1.00 19.93 ? 64 LYS B O 1 ATOM 4427 C CB . LYS B 1 64 ? -4.819 19.144 9.177 1.00 18.28 ? 64 LYS B CB 1 ATOM 4428 C CG . LYS B 1 64 ? -4.766 19.704 10.643 1.00 21.89 ? 64 LYS B CG 1 ATOM 4429 C CD . LYS B 1 64 ? -3.508 20.579 10.795 1.00 25.24 ? 64 LYS B CD 1 ATOM 4430 C CE . LYS B 1 64 ? -3.334 21.171 12.188 1.00 31.60 ? 64 LYS B CE 1 ATOM 4431 N NZ . LYS B 1 64 ? -4.276 22.305 12.468 1.00 37.26 ? 64 LYS B NZ 1 ATOM 4432 N N . HIS B 1 65 ? -7.652 20.269 8.392 1.00 20.37 ? 65 HIS B N 1 ATOM 4433 C CA . HIS B 1 65 ? -8.809 21.125 8.708 1.00 21.37 ? 65 HIS B CA 1 ATOM 4434 C C . HIS B 1 65 ? -10.120 20.329 8.699 1.00 21.09 ? 65 HIS B C 1 ATOM 4435 O O . HIS B 1 65 ? -11.039 20.643 9.447 1.00 21.47 ? 65 HIS B O 1 ATOM 4436 C CB . HIS B 1 65 ? -8.856 22.367 7.790 1.00 21.09 ? 65 HIS B CB 1 ATOM 4437 C CG . HIS B 1 65 ? -9.340 22.083 6.399 1.00 24.13 ? 65 HIS B CG 1 ATOM 4438 N ND1 . HIS B 1 65 ? -10.630 22.353 5.987 1.00 25.84 ? 65 HIS B ND1 1 ATOM 4439 C CD2 . HIS B 1 65 ? -8.708 21.556 5.323 1.00 26.68 ? 65 HIS B CD2 1 ATOM 4440 C CE1 . HIS B 1 65 ? -10.771 22.013 4.719 1.00 25.71 ? 65 HIS B CE1 1 ATOM 4441 N NE2 . HIS B 1 65 ? -9.623 21.512 4.296 1.00 28.84 ? 65 HIS B NE2 1 ATOM 4442 N N . LEU B 1 66 ? -10.201 19.276 7.878 1.00 20.55 ? 66 LEU B N 1 ATOM 4443 C CA . LEU B 1 66 ? -11.390 18.416 7.872 1.00 19.98 ? 66 LEU B CA 1 ATOM 4444 C C . LEU B 1 66 ? -11.381 17.443 9.054 1.00 19.65 ? 66 LEU B C 1 ATOM 4445 O O . LEU B 1 66 ? -12.440 17.156 9.648 1.00 18.89 ? 66 LEU B O 1 ATOM 4446 C CB . LEU B 1 66 ? -11.529 17.643 6.541 1.00 19.96 ? 66 LEU B CB 1 ATOM 4447 C CG . LEU B 1 66 ? -11.589 18.484 5.253 1.00 22.45 ? 66 LEU B CG 1 ATOM 4448 C CD1 . LEU B 1 66 ? -11.354 17.609 4.029 1.00 22.57 ? 66 LEU B CD1 1 ATOM 4449 C CD2 . LEU B 1 66 ? -12.937 19.253 5.120 1.00 23.05 ? 66 LEU B CD2 1 ATOM 4450 N N . ILE B 1 67 ? -10.190 16.947 9.412 1.00 18.83 ? 67 ILE B N 1 ATOM 4451 C CA . ILE B 1 67 ? -10.061 16.011 10.549 1.00 18.97 ? 67 ILE B CA 1 ATOM 4452 C C . ILE B 1 67 ? -10.470 16.735 11.849 1.00 20.08 ? 67 ILE B C 1 ATOM 4453 O O . ILE B 1 67 ? -11.113 16.151 12.728 1.00 20.09 ? 67 ILE B O 1 ATOM 4454 C CB . ILE B 1 67 ? -8.608 15.465 10.686 1.00 18.74 ? 67 ILE B CB 1 ATOM 4455 C CG1 . ILE B 1 67 ? -8.276 14.428 9.586 1.00 16.28 ? 67 ILE B CG1 1 ATOM 4456 C CG2 . ILE B 1 67 ? -8.373 14.879 12.055 1.00 16.60 ? 67 ILE B CG2 1 ATOM 4457 C CD1 . ILE B 1 67 ? -6.760 14.202 9.428 1.00 14.86 ? 67 ILE B CD1 1 ATOM 4458 N N . GLU B 1 68 ? -10.088 18.002 11.958 1.00 21.33 ? 68 GLU B N 1 ATOM 4459 C CA . GLU B 1 68 ? -10.430 18.824 13.145 1.00 23.56 ? 68 GLU B CA 1 ATOM 4460 C C . GLU B 1 68 ? -11.945 19.025 13.329 1.00 23.73 ? 68 GLU B C 1 ATOM 4461 O O . GLU B 1 68 ? -12.418 19.240 14.451 1.00 23.93 ? 68 GLU B O 1 ATOM 4462 C CB . GLU B 1 68 ? -9.675 20.159 13.101 1.00 23.72 ? 68 GLU B CB 1 ATOM 4463 C CG . GLU B 1 68 ? -8.264 20.043 13.694 1.00 28.10 ? 68 GLU B CG 1 ATOM 4464 C CD . GLU B 1 68 ? -7.277 21.084 13.183 1.00 31.55 ? 68 GLU B CD 1 ATOM 4465 O OE1 . GLU B 1 68 ? -7.616 21.848 12.258 1.00 33.13 ? 68 GLU B OE1 1 ATOM 4466 O OE2 . GLU B 1 68 ? -6.141 21.121 13.704 1.00 32.45 ? 68 GLU B OE2 1 ATOM 4467 N N . ARG B 1 69 ? -12.682 18.912 12.231 1.00 24.71 ? 69 ARG B N 1 ATOM 4468 C CA . ARG B 1 69 ? -14.161 19.041 12.205 1.00 26.29 ? 69 ARG B CA 1 ATOM 4469 C C . ARG B 1 69 ? -14.887 17.723 12.457 1.00 25.20 ? 69 ARG B C 1 ATOM 4470 O O . ARG B 1 69 ? -16.096 17.715 12.649 1.00 26.04 ? 69 ARG B O 1 ATOM 4471 C CB . ARG B 1 69 ? -14.621 19.635 10.858 1.00 26.17 ? 69 ARG B CB 1 ATOM 4472 C CG . ARG B 1 69 ? -14.528 21.174 10.817 1.00 32.30 ? 69 ARG B CG 1 ATOM 4473 C CD . ARG B 1 69 ? -14.624 21.789 9.403 1.00 40.10 ? 69 ARG B CD 1 ATOM 4474 N NE . ARG B 1 69 ? -15.648 21.167 8.559 1.00 45.19 ? 69 ARG B NE 1 ATOM 4475 C CZ . ARG B 1 69 ? -15.712 21.277 7.229 1.00 46.88 ? 69 ARG B CZ 1 ATOM 4476 N NH1 . ARG B 1 69 ? -14.824 22.002 6.551 1.00 46.82 ? 69 ARG B NH1 1 ATOM 4477 N NH2 . ARG B 1 69 ? -16.680 20.653 6.574 1.00 49.40 ? 69 ARG B NH2 1 ATOM 4478 N N . SER B 1 70 ? -14.142 16.617 12.457 1.00 23.96 ? 70 SER B N 1 ATOM 4479 C CA . SER B 1 70 ? -14.698 15.273 12.620 1.00 22.82 ? 70 SER B CA 1 ATOM 4480 C C . SER B 1 70 ? -15.106 15.005 14.071 1.00 22.73 ? 70 SER B C 1 ATOM 4481 O O . SER B 1 70 ? -14.361 15.326 15.015 1.00 22.18 ? 70 SER B O 1 ATOM 4482 C CB . SER B 1 70 ? -13.680 14.222 12.134 1.00 22.99 ? 70 SER B CB 1 ATOM 4483 O OG . SER B 1 70 ? -13.917 12.961 12.712 1.00 21.85 ? 70 SER B OG 1 ATOM 4484 N N . GLN B 1 71 ? -16.290 14.419 14.237 1.00 22.03 ? 71 GLN B N 1 ATOM 4485 C CA . GLN B 1 71 ? -16.806 14.047 15.546 1.00 22.22 ? 71 GLN B CA 1 ATOM 4486 C C . GLN B 1 71 ? -15.995 12.897 16.114 1.00 21.35 ? 71 GLN B C 1 ATOM 4487 O O . GLN B 1 71 ? -15.810 12.793 17.334 1.00 20.63 ? 71 GLN B O 1 ATOM 4488 C CB . GLN B 1 71 ? -18.277 13.608 15.451 1.00 22.74 ? 71 GLN B CB 1 ATOM 4489 C CG . GLN B 1 71 ? -19.263 14.740 15.245 1.00 26.68 ? 71 GLN B CG 1 ATOM 4490 C CD . GLN B 1 71 ? -19.308 15.743 16.396 1.00 30.17 ? 71 GLN B CD 1 ATOM 4491 O OE1 . GLN B 1 71 ? -19.078 15.405 17.557 1.00 32.05 ? 71 GLN B OE1 1 ATOM 4492 N NE2 . GLN B 1 71 ? -19.630 16.985 16.072 1.00 32.33 ? 71 GLN B NE2 1 ATOM 4493 N N . VAL B 1 72 ? -15.534 12.020 15.225 1.00 20.29 ? 72 VAL B N 1 ATOM 4494 C CA . VAL B 1 72 ? -14.673 10.901 15.618 1.00 19.20 ? 72 VAL B CA 1 ATOM 4495 C C . VAL B 1 72 ? -13.331 11.420 16.194 1.00 19.19 ? 72 VAL B C 1 ATOM 4496 O O . VAL B 1 72 ? -12.895 10.960 17.247 1.00 19.07 ? 72 VAL B O 1 ATOM 4497 C CB . VAL B 1 72 ? -14.424 9.950 14.416 1.00 19.91 ? 72 VAL B CB 1 ATOM 4498 C CG1 . VAL B 1 72 ? -13.288 8.971 14.723 1.00 19.99 ? 72 VAL B CG1 1 ATOM 4499 C CG2 . VAL B 1 72 ? -15.687 9.206 14.059 1.00 18.40 ? 72 VAL B CG2 1 ATOM 4500 N N . PHE B 1 73 ? -12.682 12.358 15.495 1.00 18.73 ? 73 PHE B N 1 ATOM 4501 C CA . PHE B 1 73 ? -11.482 13.026 16.001 1.00 18.89 ? 73 PHE B CA 1 ATOM 4502 C C . PHE B 1 73 ? -11.727 13.658 17.388 1.00 20.06 ? 73 PHE B C 1 ATOM 4503 O O . PHE B 1 73 ? -10.867 13.586 18.253 1.00 18.66 ? 73 PHE B O 1 ATOM 4504 C CB . PHE B 1 73 ? -11.010 14.118 15.021 1.00 18.43 ? 73 PHE B CB 1 ATOM 4505 C CG . PHE B 1 73 ? -9.778 14.870 15.487 1.00 19.30 ? 73 PHE B CG 1 ATOM 4506 C CD1 . PHE B 1 73 ? -8.532 14.228 15.536 1.00 17.68 ? 73 PHE B CD1 1 ATOM 4507 C CD2 . PHE B 1 73 ? -9.857 16.213 15.867 1.00 18.56 ? 73 PHE B CD2 1 ATOM 4508 C CE1 . PHE B 1 73 ? -7.383 14.891 15.923 1.00 18.72 ? 73 PHE B CE1 1 ATOM 4509 C CE2 . PHE B 1 73 ? -8.695 16.901 16.284 1.00 22.38 ? 73 PHE B CE2 1 ATOM 4510 C CZ . PHE B 1 73 ? -7.449 16.222 16.315 1.00 21.27 ? 73 PHE B CZ 1 ATOM 4511 N N . ASN B 1 74 ? -12.895 14.300 17.575 1.00 20.84 ? 74 ASN B N 1 ATOM 4512 C CA . ASN B 1 74 ? -13.233 14.909 18.874 1.00 21.92 ? 74 ASN B CA 1 ATOM 4513 C C . ASN B 1 74 ? -13.202 13.886 20.013 1.00 21.32 ? 74 ASN B C 1 ATOM 4514 O O . ASN B 1 74 ? -12.591 14.132 21.048 1.00 22.61 ? 74 ASN B O 1 ATOM 4515 C CB . ASN B 1 74 ? -14.579 15.662 18.805 1.00 22.45 ? 74 ASN B CB 1 ATOM 4516 C CG . ASN B 1 74 ? -14.897 16.414 20.083 1.00 25.22 ? 74 ASN B CG 1 ATOM 4517 O OD1 . ASN B 1 74 ? -14.161 17.319 20.488 1.00 28.42 ? 74 ASN B OD1 1 ATOM 4518 N ND2 . ASN B 1 74 ? -16.000 16.042 20.729 1.00 27.32 ? 74 ASN B ND2 1 ATOM 4519 N N . ILE B 1 75 ? -13.835 12.736 19.815 1.00 20.36 ? 75 ILE B N 1 ATOM 4520 C CA . ILE B 1 75 ? -13.759 11.619 20.755 1.00 19.98 ? 75 ILE B CA 1 ATOM 4521 C C . ILE B 1 75 ? -12.299 11.116 20.975 1.00 20.43 ? 75 ILE B C 1 ATOM 4522 O O . ILE B 1 75 ? -11.877 10.868 22.111 1.00 20.03 ? 75 ILE B O 1 ATOM 4523 C CB . ILE B 1 75 ? -14.701 10.476 20.311 1.00 19.80 ? 75 ILE B CB 1 ATOM 4524 C CG1 . ILE B 1 75 ? -16.184 10.890 20.531 1.00 19.50 ? 75 ILE B CG1 1 ATOM 4525 C CG2 . ILE B 1 75 ? -14.439 9.194 21.073 1.00 19.50 ? 75 ILE B CG2 1 ATOM 4526 C CD1 . ILE B 1 75 ? -17.174 10.104 19.635 1.00 19.43 ? 75 ILE B CD1 1 ATOM 4527 N N . LEU B 1 76 ? -11.536 10.975 19.901 1.00 18.92 ? 76 LEU B N 1 ATOM 4528 C CA . LEU B 1 76 ? -10.138 10.500 20.032 1.00 19.34 ? 76 LEU B CA 1 ATOM 4529 C C . LEU B 1 76 ? -9.231 11.432 20.854 1.00 19.30 ? 76 LEU B C 1 ATOM 4530 O O . LEU B 1 76 ? -8.364 10.968 21.615 1.00 19.99 ? 76 LEU B O 1 ATOM 4531 C CB . LEU B 1 76 ? -9.536 10.216 18.643 1.00 18.18 ? 76 LEU B CB 1 ATOM 4532 C CG . LEU B 1 76 ? -10.147 8.992 17.947 1.00 17.45 ? 76 LEU B CG 1 ATOM 4533 C CD1 . LEU B 1 76 ? -9.795 9.002 16.466 1.00 20.35 ? 76 LEU B CD1 1 ATOM 4534 C CD2 . LEU B 1 76 ? -9.723 7.654 18.606 1.00 18.16 ? 76 LEU B CD2 1 ATOM 4535 N N . ARG B 1 77 ? -9.435 12.733 20.694 1.00 20.96 ? 77 ARG B N 1 ATOM 4536 C CA . ARG B 1 77 ? -8.736 13.766 21.449 1.00 22.86 ? 77 ARG B CA 1 ATOM 4537 C C . ARG B 1 77 ? -8.951 13.619 22.952 1.00 22.94 ? 77 ARG B C 1 ATOM 4538 O O . ARG B 1 77 ? -8.024 13.859 23.744 1.00 22.52 ? 77 ARG B O 1 ATOM 4539 C CB . ARG B 1 77 ? -9.255 15.145 21.012 1.00 24.67 ? 77 ARG B CB 1 ATOM 4540 C CG . ARG B 1 77 ? -8.661 15.652 19.717 1.00 27.18 ? 77 ARG B CG 1 ATOM 4541 C CD . ARG B 1 77 ? -7.470 16.564 19.948 1.00 34.98 ? 77 ARG B CD 1 ATOM 4542 N NE . ARG B 1 77 ? -7.768 17.696 20.827 1.00 40.57 ? 77 ARG B NE 1 ATOM 4543 C CZ . ARG B 1 77 ? -8.743 18.590 20.626 1.00 45.62 ? 77 ARG B CZ 1 ATOM 4544 N NH1 . ARG B 1 77 ? -9.565 18.487 19.581 1.00 46.05 ? 77 ARG B NH1 1 ATOM 4545 N NH2 . ARG B 1 77 ? -8.918 19.591 21.495 1.00 47.02 ? 77 ARG B NH2 1 ATOM 4546 N N . MET B 1 78 ? -10.183 13.238 23.318 1.00 22.57 ? 78 MET B N 1 ATOM 4547 C CA . MET B 1 78 ? -10.615 12.977 24.701 1.00 22.89 ? 78 MET B CA 1 ATOM 4548 C C . MET B 1 78 ? -10.106 11.646 25.285 1.00 21.52 ? 78 MET B C 1 ATOM 4549 O O . MET B 1 78 ? -9.983 11.500 26.504 1.00 21.28 ? 78 MET B O 1 ATOM 4550 C CB . MET B 1 78 ? -12.154 12.928 24.763 1.00 23.42 ? 78 MET B CB 1 ATOM 4551 C CG . MET B 1 78 ? -12.840 14.285 24.800 1.00 28.79 ? 78 MET B CG 1 ATOM 4552 S SD . MET B 1 78 ? -14.636 14.185 24.423 1.00 39.72 ? 78 MET B SD 1 ATOM 4553 C CE . MET B 1 78 ? -15.172 12.667 25.213 1.00 35.63 ? 78 MET B CE 1 ATOM 4554 N N . MET B 1 79 ? -9.886 10.659 24.427 1.00 19.37 ? 79 MET B N 1 ATOM 4555 C CA . MET B 1 79 ? -9.469 9.353 24.862 1.00 19.75 ? 79 MET B CA 1 ATOM 4556 C C . MET B 1 79 ? -8.086 9.419 25.567 1.00 19.31 ? 79 MET B C 1 ATOM 4557 O O . MET B 1 79 ? -7.184 10.059 25.046 1.00 19.57 ? 79 MET B O 1 ATOM 4558 C CB . MET B 1 79 ? -9.394 8.421 23.630 1.00 19.07 ? 79 MET B CB 1 ATOM 4559 C CG . MET B 1 79 ? -9.262 6.955 23.980 1.00 21.02 ? 79 MET B CG 1 ATOM 4560 S SD . MET B 1 79 ? -9.282 5.830 22.542 1.00 26.75 ? 79 MET B SD 1 ATOM 4561 C CE . MET B 1 79 ? -7.646 6.061 21.953 1.00 25.05 ? 79 MET B CE 1 ATOM 4562 N N . PRO B 1 80 ? -7.923 8.748 26.732 1.00 18.93 ? 80 PRO B N 1 ATOM 4563 C CA . PRO B 1 80 ? -6.555 8.529 27.261 1.00 19.43 ? 80 PRO B CA 1 ATOM 4564 C C . PRO B 1 80 ? -5.853 7.450 26.418 1.00 19.37 ? 80 PRO B C 1 ATOM 4565 O O . PRO B 1 80 ? -6.316 6.312 26.370 1.00 19.80 ? 80 PRO B O 1 ATOM 4566 C CB . PRO B 1 80 ? -6.781 8.027 28.685 1.00 19.05 ? 80 PRO B CB 1 ATOM 4567 C CG . PRO B 1 80 ? -8.248 7.465 28.672 1.00 19.24 ? 80 PRO B CG 1 ATOM 4568 C CD . PRO B 1 80 ? -8.949 7.984 27.474 1.00 18.97 ? 80 PRO B CD 1 ATOM 4569 N N . LYS B 1 81 ? -4.763 7.837 25.746 1.00 19.40 ? 81 LYS B N 1 ATOM 4570 C CA . LYS B 1 81 ? -4.144 7.034 24.701 1.00 19.16 ? 81 LYS B CA 1 ATOM 4571 C C . LYS B 1 81 ? -2.963 6.241 25.283 1.00 19.64 ? 81 LYS B C 1 ATOM 4572 O O . LYS B 1 81 ? -2.354 5.411 24.618 1.00 20.34 ? 81 LYS B O 1 ATOM 4573 C CB . LYS B 1 81 ? -3.754 7.962 23.527 1.00 19.29 ? 81 LYS B CB 1 ATOM 4574 C CG . LYS B 1 81 ? -4.956 8.264 22.592 1.00 17.35 ? 81 LYS B CG 1 ATOM 4575 C CD . LYS B 1 81 ? -4.829 9.525 21.691 1.00 15.89 ? 81 LYS B CD 1 ATOM 4576 C CE . LYS B 1 81 ? -4.714 10.838 22.507 1.00 15.31 ? 81 LYS B CE 1 ATOM 4577 N NZ . LYS B 1 81 ? -6.032 11.466 22.915 1.00 14.07 ? 81 LYS B NZ 1 ATOM 4578 N N . GLY B 1 82 ? -2.679 6.471 26.558 1.00 20.05 ? 82 GLY B N 1 ATOM 4579 C CA . GLY B 1 82 ? -1.602 5.741 27.249 1.00 19.34 ? 82 GLY B CA 1 ATOM 4580 C C . GLY B 1 82 ? -0.312 6.537 27.102 1.00 18.44 ? 82 GLY B C 1 ATOM 4581 O O . GLY B 1 82 ? -0.184 7.597 27.696 1.00 18.69 ? 82 GLY B O 1 ATOM 4582 N N . ALA B 1 83 ? 0.608 6.021 26.282 1.00 17.29 ? 83 ALA B N 1 ATOM 4583 C CA . ALA B 1 83 ? 1.987 6.521 26.176 1.00 16.25 ? 83 ALA B CA 1 ATOM 4584 C C . ALA B 1 83 ? 2.378 6.824 24.721 1.00 15.62 ? 83 ALA B C 1 ATOM 4585 O O . ALA B 1 83 ? 1.892 6.154 23.782 1.00 16.10 ? 83 ALA B O 1 ATOM 4586 C CB . ALA B 1 83 ? 2.978 5.453 26.786 1.00 16.23 ? 83 ALA B CB 1 ATOM 4587 N N . ALA B 1 84 ? 3.231 7.827 24.529 1.00 15.44 ? 84 ALA B N 1 ATOM 4588 C CA . ALA B 1 84 ? 3.831 8.112 23.196 1.00 15.38 ? 84 ALA B CA 1 ATOM 4589 C C . ALA B 1 84 ? 5.243 7.536 23.172 1.00 14.89 ? 84 ALA B C 1 ATOM 4590 O O . ALA B 1 84 ? 6.113 8.038 23.901 1.00 14.38 ? 84 ALA B O 1 ATOM 4591 C CB . ALA B 1 84 ? 3.872 9.622 22.930 1.00 14.77 ? 84 ALA B CB 1 ATOM 4592 N N . LEU B 1 85 ? 5.463 6.474 22.378 1.00 15.32 ? 85 LEU B N 1 ATOM 4593 C CA . LEU B 1 85 ? 6.698 5.683 22.488 1.00 16.03 ? 85 LEU B CA 1 ATOM 4594 C C . LEU B 1 85 ? 7.735 5.896 21.367 1.00 16.97 ? 85 LEU B C 1 ATOM 4595 O O . LEU B 1 85 ? 8.860 5.412 21.474 1.00 16.48 ? 85 LEU B O 1 ATOM 4596 C CB . LEU B 1 85 ? 6.384 4.187 22.667 1.00 15.77 ? 85 LEU B CB 1 ATOM 4597 C CG . LEU B 1 85 ? 5.672 3.714 23.944 1.00 15.44 ? 85 LEU B CG 1 ATOM 4598 C CD1 . LEU B 1 85 ? 5.524 2.198 23.858 1.00 15.64 ? 85 LEU B CD1 1 ATOM 4599 C CD2 . LEU B 1 85 ? 6.391 4.126 25.253 1.00 16.61 ? 85 LEU B CD2 1 ATOM 4600 N N . HIS B 1 86 ? 7.368 6.669 20.341 1.00 16.20 ? 86 HIS B N 1 ATOM 4601 C CA . HIS B 1 86 ? 8.274 6.980 19.249 1.00 16.73 ? 86 HIS B CA 1 ATOM 4602 C C . HIS B 1 86 ? 8.154 8.462 18.951 1.00 16.29 ? 86 HIS B C 1 ATOM 4603 O O . HIS B 1 86 ? 7.213 8.903 18.273 1.00 16.30 ? 86 HIS B O 1 ATOM 4604 C CB . HIS B 1 86 ? 7.907 6.156 18.008 1.00 16.77 ? 86 HIS B CB 1 ATOM 4605 C CG . HIS B 1 86 ? 8.882 6.291 16.888 1.00 19.97 ? 86 HIS B CG 1 ATOM 4606 N ND1 . HIS B 1 86 ? 9.623 5.224 16.419 1.00 22.95 ? 86 HIS B ND1 1 ATOM 4607 C CD2 . HIS B 1 86 ? 9.224 7.354 16.118 1.00 21.33 ? 86 HIS B CD2 1 ATOM 4608 C CE1 . HIS B 1 86 ? 10.397 5.624 15.426 1.00 21.03 ? 86 HIS B CE1 1 ATOM 4609 N NE2 . HIS B 1 86 ? 10.170 6.908 15.217 1.00 24.73 ? 86 HIS B NE2 1 ATOM 4610 N N . LEU B 1 87 ? 9.078 9.230 19.506 1.00 16.36 ? 87 LEU B N 1 ATOM 4611 C CA . LEU B 1 87 ? 9.105 10.688 19.357 1.00 16.73 ? 87 LEU B CA 1 ATOM 4612 C C . LEU B 1 87 ? 10.561 11.103 19.223 1.00 17.78 ? 87 LEU B C 1 ATOM 4613 O O . LEU B 1 87 ? 11.429 10.466 19.810 1.00 17.94 ? 87 LEU B O 1 ATOM 4614 C CB . LEU B 1 87 ? 8.547 11.392 20.614 1.00 15.87 ? 87 LEU B CB 1 ATOM 4615 C CG . LEU B 1 87 ? 7.077 11.160 21.056 1.00 15.72 ? 87 LEU B CG 1 ATOM 4616 C CD1 . LEU B 1 87 ? 6.864 11.820 22.391 1.00 15.07 ? 87 LEU B CD1 1 ATOM 4617 C CD2 . LEU B 1 87 ? 6.067 11.696 20.032 1.00 13.34 ? 87 LEU B CD2 1 ATOM 4618 N N . HIS B 1 88 ? 10.816 12.188 18.508 1.00 18.89 ? 88 HIS B N 1 ATOM 4619 C CA . HIS B 1 88 ? 12.162 12.761 18.438 1.00 21.56 ? 88 HIS B CA 1 ATOM 4620 C C . HIS B 1 88 ? 12.258 14.040 19.248 1.00 22.55 ? 88 HIS B C 1 ATOM 4621 O O . HIS B 1 88 ? 11.258 14.771 19.379 1.00 22.94 ? 88 HIS B O 1 ATOM 4622 C CB . HIS B 1 88 ? 12.534 13.036 16.978 1.00 22.01 ? 88 HIS B CB 1 ATOM 4623 C CG . HIS B 1 88 ? 12.741 11.782 16.193 1.00 24.70 ? 88 HIS B CG 1 ATOM 4624 N ND1 . HIS B 1 88 ? 13.982 11.202 16.033 1.00 25.92 ? 88 HIS B ND1 1 ATOM 4625 C CD2 . HIS B 1 88 ? 11.858 10.959 15.584 1.00 26.12 ? 88 HIS B CD2 1 ATOM 4626 C CE1 . HIS B 1 88 ? 13.857 10.086 15.336 1.00 27.33 ? 88 HIS B CE1 1 ATOM 4627 N NE2 . HIS B 1 88 ? 12.578 9.916 15.048 1.00 28.58 ? 88 HIS B NE2 1 ATOM 4628 N N . ASP B 1 89 ? 13.461 14.320 19.749 1.00 23.35 ? 89 ASP B N 1 ATOM 4629 C CA . ASP B 1 89 ? 13.698 15.438 20.687 1.00 24.80 ? 89 ASP B CA 1 ATOM 4630 C C . ASP B 1 89 ? 13.194 16.815 20.279 1.00 24.48 ? 89 ASP B C 1 ATOM 4631 O O . ASP B 1 89 ? 12.736 17.556 21.139 1.00 25.65 ? 89 ASP B O 1 ATOM 4632 C CB . ASP B 1 89 ? 15.176 15.535 21.111 1.00 25.13 ? 89 ASP B CB 1 ATOM 4633 C CG . ASP B 1 89 ? 16.140 15.498 19.932 1.00 28.33 ? 89 ASP B CG 1 ATOM 4634 O OD1 . ASP B 1 89 ? 15.702 15.678 18.767 1.00 31.61 ? 89 ASP B OD1 1 ATOM 4635 O OD2 . ASP B 1 89 ? 17.348 15.274 20.173 1.00 31.70 ? 89 ASP B OD2 1 ATOM 4636 N N . ILE B 1 90 ? 13.280 17.176 19.002 1.00 23.85 ? 90 ILE B N 1 ATOM 4637 C CA . ILE B 1 90 ? 12.947 18.546 18.618 1.00 23.64 ? 90 ILE B CA 1 ATOM 4638 C C . ILE B 1 90 ? 11.751 18.728 17.680 1.00 22.96 ? 90 ILE B C 1 ATOM 4639 O O . ILE B 1 90 ? 11.600 19.783 17.057 1.00 23.31 ? 90 ILE B O 1 ATOM 4640 C CB . ILE B 1 90 ? 14.179 19.375 18.130 1.00 24.48 ? 90 ILE B CB 1 ATOM 4641 C CG1 . ILE B 1 90 ? 14.720 18.842 16.816 1.00 26.78 ? 90 ILE B CG1 1 ATOM 4642 C CG2 . ILE B 1 90 ? 15.296 19.452 19.219 1.00 24.24 ? 90 ILE B CG2 1 ATOM 4643 C CD1 . ILE B 1 90 ? 15.745 19.804 16.145 1.00 28.81 ? 90 ILE B CD1 1 ATOM 4644 N N . GLY B 1 91 ? 10.869 17.731 17.628 1.00 22.38 ? 91 GLY B N 1 ATOM 4645 C CA . GLY B 1 91 ? 9.713 17.781 16.745 1.00 21.18 ? 91 GLY B CA 1 ATOM 4646 C C . GLY B 1 91 ? 8.398 17.680 17.476 1.00 21.09 ? 91 GLY B C 1 ATOM 4647 O O . GLY B 1 91 ? 7.385 17.345 16.862 1.00 20.75 ? 91 GLY B O 1 ATOM 4648 N N . ILE B 1 92 ? 8.395 18.014 18.771 1.00 20.00 ? 92 ILE B N 1 ATOM 4649 C CA . ILE B 1 92 ? 7.262 17.664 19.635 1.00 20.49 ? 92 ILE B CA 1 ATOM 4650 C C . ILE B 1 92 ? 6.589 18.822 20.374 1.00 21.24 ? 92 ILE B C 1 ATOM 4651 O O . ILE B 1 92 ? 5.857 18.599 21.367 1.00 21.66 ? 92 ILE B O 1 ATOM 4652 C CB . ILE B 1 92 ? 7.662 16.563 20.651 1.00 20.18 ? 92 ILE B CB 1 ATOM 4653 C CG1 . ILE B 1 92 ? 8.956 16.956 21.397 1.00 19.87 ? 92 ILE B CG1 1 ATOM 4654 C CG2 . ILE B 1 92 ? 7.790 15.209 19.937 1.00 20.46 ? 92 ILE B CG2 1 ATOM 4655 C CD1 . ILE B 1 92 ? 9.314 16.003 22.551 1.00 18.53 ? 92 ILE B CD1 1 ATOM 4656 N N . VAL B 1 93 ? 6.842 20.042 19.888 1.00 21.18 ? 93 VAL B N 1 ATOM 4657 C CA . VAL B 1 93 ? 6.291 21.264 20.445 1.00 21.28 ? 93 VAL B CA 1 ATOM 4658 C C . VAL B 1 93 ? 5.816 22.104 19.251 1.00 22.41 ? 93 VAL B C 1 ATOM 4659 O O . VAL B 1 93 ? 6.589 22.401 18.335 1.00 21.44 ? 93 VAL B O 1 ATOM 4660 C CB . VAL B 1 93 ? 7.361 22.043 21.278 1.00 21.35 ? 93 VAL B CB 1 ATOM 4661 C CG1 . VAL B 1 93 ? 6.870 23.443 21.668 1.00 20.55 ? 93 VAL B CG1 1 ATOM 4662 C CG2 . VAL B 1 93 ? 7.803 21.233 22.527 1.00 19.59 ? 93 VAL B CG2 1 ATOM 4663 N N . THR B 1 94 ? 4.534 22.449 19.249 1.00 23.63 ? 94 THR B N 1 ATOM 4664 C CA . THR B 1 94 ? 3.963 23.264 18.170 1.00 25.01 ? 94 THR B CA 1 ATOM 4665 C C . THR B 1 94 ? 4.857 24.474 17.892 1.00 25.56 ? 94 THR B C 1 ATOM 4666 O O . THR B 1 94 ? 5.284 25.176 18.825 1.00 25.13 ? 94 THR B O 1 ATOM 4667 C CB . THR B 1 94 ? 2.519 23.671 18.503 1.00 24.78 ? 94 THR B CB 1 ATOM 4668 O OG1 . THR B 1 94 ? 1.782 22.477 18.782 1.00 27.24 ? 94 THR B OG1 1 ATOM 4669 C CG2 . THR B 1 94 ? 1.858 24.377 17.334 1.00 24.24 ? 94 THR B CG2 1 ATOM 4670 N N . MET B 1 95 ? 5.161 24.688 16.610 1.00 26.46 ? 95 MET B N 1 ATOM 4671 C CA . MET B 1 95 ? 6.190 25.660 16.180 1.00 27.62 ? 95 MET B CA 1 ATOM 4672 C C . MET B 1 95 ? 5.805 27.132 16.403 1.00 28.82 ? 95 MET B C 1 ATOM 4673 O O . MET B 1 95 ? 6.676 27.996 16.511 1.00 28.17 ? 95 MET B O 1 ATOM 4674 C CB . MET B 1 95 ? 6.571 25.439 14.709 1.00 27.66 ? 95 MET B CB 1 ATOM 4675 C CG . MET B 1 95 ? 7.265 24.120 14.422 1.00 27.76 ? 95 MET B CG 1 ATOM 4676 S SD . MET B 1 95 ? 8.845 24.018 15.274 1.00 30.82 ? 95 MET B SD 1 ATOM 4677 C CE . MET B 1 95 ? 9.484 22.505 14.558 1.00 32.92 ? 95 MET B CE 1 ATOM 4678 N N . ASP B 1 96 ? 4.500 27.387 16.433 1.00 30.20 ? 96 ASP B N 1 ATOM 4679 C CA . ASP B 1 96 ? 3.905 28.666 16.805 1.00 32.65 ? 96 ASP B CA 1 ATOM 4680 C C . ASP B 1 96 ? 4.557 29.277 18.066 1.00 32.75 ? 96 ASP B C 1 ATOM 4681 O O . ASP B 1 96 ? 4.926 30.462 18.077 1.00 33.00 ? 96 ASP B O 1 ATOM 4682 C CB . ASP B 1 96 ? 2.416 28.430 17.061 1.00 33.44 ? 96 ASP B CB 1 ATOM 4683 C CG . ASP B 1 96 ? 1.541 29.413 16.347 1.00 38.71 ? 96 ASP B CG 1 ATOM 4684 O OD1 . ASP B 1 96 ? 1.486 30.589 16.794 1.00 43.63 ? 96 ASP B OD1 1 ATOM 4685 O OD2 . ASP B 1 96 ? 0.878 29.008 15.355 1.00 42.36 ? 96 ASP B OD2 1 ATOM 4686 N N . TRP B 1 97 ? 4.720 28.460 19.113 1.00 32.80 ? 97 TRP B N 1 ATOM 4687 C CA . TRP B 1 97 ? 5.423 28.892 20.345 1.00 32.74 ? 97 TRP B CA 1 ATOM 4688 C C . TRP B 1 97 ? 6.883 29.248 20.104 1.00 32.70 ? 97 TRP B C 1 ATOM 4689 O O . TRP B 1 97 ? 7.363 30.204 20.686 1.00 32.62 ? 97 TRP B O 1 ATOM 4690 C CB . TRP B 1 97 ? 5.321 27.832 21.446 1.00 32.95 ? 97 TRP B CB 1 ATOM 4691 C CG . TRP B 1 97 ? 6.097 28.134 22.743 1.00 32.07 ? 97 TRP B CG 1 ATOM 4692 C CD1 . TRP B 1 97 ? 5.682 28.927 23.775 1.00 32.69 ? 97 TRP B CD1 1 ATOM 4693 C CD2 . TRP B 1 97 ? 7.383 27.610 23.135 1.00 31.53 ? 97 TRP B CD2 1 ATOM 4694 N NE1 . TRP B 1 97 ? 6.626 28.941 24.783 1.00 32.74 ? 97 TRP B NE1 1 ATOM 4695 C CE2 . TRP B 1 97 ? 7.677 28.136 24.423 1.00 31.52 ? 97 TRP B CE2 1 ATOM 4696 C CE3 . TRP B 1 97 ? 8.305 26.742 22.535 1.00 28.90 ? 97 TRP B CE3 1 ATOM 4697 C CZ2 . TRP B 1 97 ? 8.863 27.834 25.110 1.00 29.97 ? 97 TRP B CZ2 1 ATOM 4698 C CZ3 . TRP B 1 97 ? 9.489 26.437 23.219 1.00 29.55 ? 97 TRP B CZ3 1 ATOM 4699 C CH2 . TRP B 1 97 ? 9.755 26.984 24.496 1.00 30.53 ? 97 TRP B CH2 1 ATOM 4700 N N . LEU B 1 98 ? 7.593 28.492 19.258 1.00 33.12 ? 98 LEU B N 1 ATOM 4701 C CA . LEU B 1 98 ? 9.001 28.816 18.942 1.00 33.28 ? 98 LEU B CA 1 ATOM 4702 C C . LEU B 1 98 ? 9.158 30.201 18.331 1.00 34.31 ? 98 LEU B C 1 ATOM 4703 O O . LEU B 1 98 ? 10.157 30.875 18.564 1.00 34.31 ? 98 LEU B O 1 ATOM 4704 C CB . LEU B 1 98 ? 9.637 27.801 17.981 1.00 33.22 ? 98 LEU B CB 1 ATOM 4705 C CG . LEU B 1 98 ? 10.552 26.665 18.440 1.00 33.37 ? 98 LEU B CG 1 ATOM 4706 C CD1 . LEU B 1 98 ? 11.338 26.120 17.234 1.00 32.52 ? 98 LEU B CD1 1 ATOM 4707 C CD2 . LEU B 1 98 ? 11.495 27.053 19.562 1.00 28.98 ? 98 LEU B CD2 1 ATOM 4708 N N . VAL B 1 99 ? 8.178 30.596 17.523 1.00 35.34 ? 99 VAL B N 1 ATOM 4709 C CA . VAL B 1 99 ? 8.131 31.930 16.909 1.00 36.49 ? 99 VAL B CA 1 ATOM 4710 C C . VAL B 1 99 ? 7.585 33.023 17.857 1.00 37.11 ? 99 VAL B C 1 ATOM 4711 O O . VAL B 1 99 ? 8.325 33.927 18.226 1.00 37.63 ? 99 VAL B O 1 ATOM 4712 C CB . VAL B 1 99 ? 7.343 31.906 15.563 1.00 36.34 ? 99 VAL B CB 1 ATOM 4713 C CG1 . VAL B 1 99 ? 7.187 33.309 14.996 1.00 36.96 ? 99 VAL B CG1 1 ATOM 4714 C CG2 . VAL B 1 99 ? 8.038 30.992 14.552 1.00 35.55 ? 99 VAL B CG2 1 ATOM 4715 N N . ARG B 1 100 ? 6.313 32.936 18.251 1.00 38.42 ? 100 ARG B N 1 ATOM 4716 C CA . ARG B 1 100 ? 5.668 34.001 19.048 1.00 39.65 ? 100 ARG B CA 1 ATOM 4717 C C . ARG B 1 100 ? 6.349 34.229 20.406 1.00 39.24 ? 100 ARG B C 1 ATOM 4718 O O . ARG B 1 100 ? 6.428 35.365 20.879 1.00 39.93 ? 100 ARG B O 1 ATOM 4719 C CB . ARG B 1 100 ? 4.168 33.727 19.254 1.00 40.02 ? 100 ARG B CB 1 ATOM 4720 C CG . ARG B 1 100 ? 3.246 34.162 18.090 1.00 44.15 ? 100 ARG B CG 1 ATOM 4721 C CD . ARG B 1 100 ? 2.546 35.533 18.349 1.00 49.24 ? 100 ARG B CD 1 ATOM 4722 N NE . ARG B 1 100 ? 3.483 36.669 18.372 1.00 53.13 ? 100 ARG B NE 1 ATOM 4723 C CZ . ARG B 1 100 ? 3.778 37.395 19.452 1.00 54.28 ? 100 ARG B CZ 1 ATOM 4724 N NH1 . ARG B 1 100 ? 3.196 37.138 20.618 1.00 55.18 ? 100 ARG B NH1 1 ATOM 4725 N NH2 . ARG B 1 100 ? 4.654 38.392 19.361 1.00 55.07 ? 100 ARG B NH2 1 ATOM 4726 N N . ASN B 1 101 ? 6.856 33.155 21.005 1.00 38.06 ? 101 ASN B N 1 ATOM 4727 C CA . ASN B 1 101 ? 7.450 33.212 22.337 1.00 37.07 ? 101 ASN B CA 1 ATOM 4728 C C . ASN B 1 101 ? 8.985 33.249 22.318 1.00 36.29 ? 101 ASN B C 1 ATOM 4729 O O . ASN B 1 101 ? 9.580 34.266 22.682 1.00 36.03 ? 101 ASN B O 1 ATOM 4730 C CB . ASN B 1 101 ? 6.908 32.043 23.175 1.00 37.12 ? 101 ASN B CB 1 ATOM 4731 C CG . ASN B 1 101 ? 7.312 32.111 24.650 1.00 38.54 ? 101 ASN B CG 1 ATOM 4732 O OD1 . ASN B 1 101 ? 8.500 32.196 24.990 1.00 37.00 ? 101 ASN B OD1 1 ATOM 4733 N ND2 . ASN B 1 101 ? 6.301 32.042 25.528 1.00 39.72 ? 101 ASN B ND2 1 ATOM 4734 N N . VAL B 1 102 ? 9.625 32.163 21.870 1.00 35.34 ? 102 VAL B N 1 ATOM 4735 C CA . VAL B 1 102 ? 11.089 32.005 21.978 1.00 34.35 ? 102 VAL B CA 1 ATOM 4736 C C . VAL B 1 102 ? 11.885 33.056 21.199 1.00 35.07 ? 102 VAL B C 1 ATOM 4737 O O . VAL B 1 102 ? 12.934 33.543 21.651 1.00 34.35 ? 102 VAL B O 1 ATOM 4738 C CB . VAL B 1 102 ? 11.544 30.590 21.541 1.00 34.14 ? 102 VAL B CB 1 ATOM 4739 C CG1 . VAL B 1 102 ? 13.065 30.471 21.533 1.00 30.87 ? 102 VAL B CG1 1 ATOM 4740 C CG2 . VAL B 1 102 ? 10.919 29.530 22.441 1.00 33.94 ? 102 VAL B CG2 1 ATOM 4741 N N . THR B 1 103 ? 11.384 33.400 20.023 1.00 35.89 ? 103 THR B N 1 ATOM 4742 C CA . THR B 1 103 ? 12.092 34.305 19.138 1.00 37.01 ? 103 THR B CA 1 ATOM 4743 C C . THR B 1 103 ? 11.896 35.785 19.549 1.00 37.69 ? 103 THR B C 1 ATOM 4744 O O . THR B 1 103 ? 12.563 36.686 19.035 1.00 37.93 ? 103 THR B O 1 ATOM 4745 C CB . THR B 1 103 ? 11.734 33.975 17.659 1.00 37.32 ? 103 THR B CB 1 ATOM 4746 O OG1 . THR B 1 103 ? 12.920 33.943 16.863 1.00 38.53 ? 103 THR B OG1 1 ATOM 4747 C CG2 . THR B 1 103 ? 10.711 34.905 17.094 1.00 35.34 ? 103 THR B CG2 1 ATOM 4748 N N . TYR B 1 104 ? 11.000 36.014 20.503 1.00 38.77 ? 104 TYR B N 1 ATOM 4749 C CA . TYR B 1 104 ? 10.857 37.323 21.140 1.00 39.63 ? 104 TYR B CA 1 ATOM 4750 C C . TYR B 1 104 ? 11.607 37.453 22.479 1.00 39.77 ? 104 TYR B C 1 ATOM 4751 O O . TYR B 1 104 ? 11.537 38.490 23.151 1.00 40.23 ? 104 TYR B O 1 ATOM 4752 C CB . TYR B 1 104 ? 9.381 37.671 21.292 1.00 39.94 ? 104 TYR B CB 1 ATOM 4753 C CG . TYR B 1 104 ? 8.791 38.173 20.003 1.00 42.17 ? 104 TYR B CG 1 ATOM 4754 C CD1 . TYR B 1 104 ? 8.196 37.293 19.092 1.00 43.44 ? 104 TYR B CD1 1 ATOM 4755 C CD2 . TYR B 1 104 ? 8.859 39.530 19.670 1.00 43.86 ? 104 TYR B CD2 1 ATOM 4756 C CE1 . TYR B 1 104 ? 7.662 37.757 17.898 1.00 45.13 ? 104 TYR B CE1 1 ATOM 4757 C CE2 . TYR B 1 104 ? 8.332 39.999 18.488 1.00 44.49 ? 104 TYR B CE2 1 ATOM 4758 C CZ . TYR B 1 104 ? 7.735 39.115 17.607 1.00 46.00 ? 104 TYR B CZ 1 ATOM 4759 O OH . TYR B 1 104 ? 7.224 39.593 16.427 1.00 47.40 ? 104 TYR B OH 1 ATOM 4760 N N . ARG B 1 105 ? 12.345 36.410 22.854 1.00 39.80 ? 105 ARG B N 1 ATOM 4761 C CA . ARG B 1 105 ? 13.151 36.454 24.064 1.00 39.24 ? 105 ARG B CA 1 ATOM 4762 C C . ARG B 1 105 ? 14.422 37.246 23.829 1.00 39.66 ? 105 ARG B C 1 ATOM 4763 O O . ARG B 1 105 ? 15.015 37.151 22.752 1.00 39.46 ? 105 ARG B O 1 ATOM 4764 C CB . ARG B 1 105 ? 13.496 35.054 24.559 1.00 38.85 ? 105 ARG B CB 1 ATOM 4765 C CG . ARG B 1 105 ? 12.292 34.297 25.072 1.00 37.21 ? 105 ARG B CG 1 ATOM 4766 C CD . ARG B 1 105 ? 12.664 32.890 25.464 1.00 34.19 ? 105 ARG B CD 1 ATOM 4767 N NE . ARG B 1 105 ? 11.482 32.121 25.856 1.00 29.99 ? 105 ARG B NE 1 ATOM 4768 C CZ . ARG B 1 105 ? 11.492 31.118 26.725 1.00 29.47 ? 105 ARG B CZ 1 ATOM 4769 N NH1 . ARG B 1 105 ? 12.616 30.760 27.326 1.00 27.85 ? 105 ARG B NH1 1 ATOM 4770 N NH2 . ARG B 1 105 ? 10.362 30.487 27.009 1.00 29.45 ? 105 ARG B NH2 1 ATOM 4771 N N . PRO B 1 106 ? 14.844 38.032 24.845 1.00 39.70 ? 106 PRO B N 1 ATOM 4772 C CA . PRO B 1 106 ? 16.083 38.800 24.819 1.00 39.67 ? 106 PRO B CA 1 ATOM 4773 C C . PRO B 1 106 ? 17.271 37.971 24.375 1.00 39.51 ? 106 PRO B C 1 ATOM 4774 O O . PRO B 1 106 ? 17.358 36.787 24.713 1.00 39.12 ? 106 PRO B O 1 ATOM 4775 C CB . PRO B 1 106 ? 16.272 39.241 26.287 1.00 39.58 ? 106 PRO B CB 1 ATOM 4776 C CG . PRO B 1 106 ? 15.060 38.727 27.050 1.00 40.36 ? 106 PRO B CG 1 ATOM 4777 C CD . PRO B 1 106 ? 14.020 38.406 26.006 1.00 39.94 ? 106 PRO B CD 1 ATOM 4778 N N . HIS B 1 107 ? 18.168 38.612 23.625 1.00 39.18 ? 107 HIS B N 1 ATOM 4779 C CA . HIS B 1 107 ? 19.463 38.054 23.211 1.00 39.78 ? 107 HIS B CA 1 ATOM 4780 C C . HIS B 1 107 ? 19.399 37.042 22.041 1.00 39.36 ? 107 HIS B C 1 ATOM 4781 O O . HIS B 1 107 ? 20.404 36.403 21.693 1.00 38.82 ? 107 HIS B O 1 ATOM 4782 C CB . HIS B 1 107 ? 20.257 37.516 24.412 1.00 40.20 ? 107 HIS B CB 1 ATOM 4783 C CG . HIS B 1 107 ? 20.142 38.368 25.645 1.00 42.93 ? 107 HIS B CG 1 ATOM 4784 N ND1 . HIS B 1 107 ? 20.725 39.616 25.752 1.00 46.39 ? 107 HIS B ND1 1 ATOM 4785 C CD2 . HIS B 1 107 ? 19.510 38.148 26.824 1.00 43.61 ? 107 HIS B CD2 1 ATOM 4786 C CE1 . HIS B 1 107 ? 20.450 40.130 26.939 1.00 45.81 ? 107 HIS B CE1 1 ATOM 4787 N NE2 . HIS B 1 107 ? 19.713 39.260 27.609 1.00 45.78 ? 107 HIS B NE2 1 ATOM 4788 N N . CYS B 1 108 ? 18.224 36.933 21.423 1.00 39.59 ? 108 CYS B N 1 ATOM 4789 C CA . CYS B 1 108 ? 18.030 36.065 20.256 1.00 39.97 ? 108 CYS B CA 1 ATOM 4790 C C . CYS B 1 108 ? 18.504 36.732 18.964 1.00 40.41 ? 108 CYS B C 1 ATOM 4791 O O . CYS B 1 108 ? 17.971 37.772 18.573 1.00 40.17 ? 108 CYS B O 1 ATOM 4792 C CB . CYS B 1 108 ? 16.556 35.670 20.115 1.00 40.01 ? 108 CYS B CB 1 ATOM 4793 S SG . CYS B 1 108 ? 16.272 34.390 18.839 1.00 39.34 ? 108 CYS B SG 1 ATOM 4794 N N . HIS B 1 109 ? 19.504 36.127 18.323 1.00 41.10 ? 109 HIS B N 1 ATOM 4795 C CA . HIS B 1 109 ? 20.008 36.571 17.026 1.00 42.12 ? 109 HIS B CA 1 ATOM 4796 C C . HIS B 1 109 ? 19.531 35.642 15.883 1.00 42.93 ? 109 HIS B C 1 ATOM 4797 O O . HIS B 1 109 ? 19.204 34.464 16.121 1.00 42.91 ? 109 HIS B O 1 ATOM 4798 C CB . HIS B 1 109 ? 21.539 36.588 17.029 1.00 42.12 ? 109 HIS B CB 1 ATOM 4799 C CG . HIS B 1 109 ? 22.147 37.557 18.001 1.00 44.82 ? 109 HIS B CG 1 ATOM 4800 N ND1 . HIS B 1 109 ? 22.257 37.293 19.352 1.00 46.23 ? 109 HIS B ND1 1 ATOM 4801 C CD2 . HIS B 1 109 ? 22.707 38.778 17.811 1.00 46.31 ? 109 HIS B CD2 1 ATOM 4802 C CE1 . HIS B 1 109 ? 22.848 38.313 19.951 1.00 47.41 ? 109 HIS B CE1 1 ATOM 4803 N NE2 . HIS B 1 109 ? 23.132 39.227 19.038 1.00 47.02 ? 109 HIS B NE2 1 ATOM 4804 N N . ILE B 1 110 ? 19.493 36.190 14.664 1.00 43.45 ? 110 ILE B N 1 ATOM 4805 C CA . ILE B 1 110 ? 19.273 35.443 13.408 1.00 44.33 ? 110 ILE B CA 1 ATOM 4806 C C . ILE B 1 110 ? 20.397 35.767 12.431 1.00 45.35 ? 110 ILE B C 1 ATOM 4807 O O . ILE B 1 110 ? 20.922 36.884 12.444 1.00 45.26 ? 110 ILE B O 1 ATOM 4808 C CB . ILE B 1 110 ? 17.893 35.777 12.751 1.00 44.40 ? 110 ILE B CB 1 ATOM 4809 C CG1 . ILE B 1 110 ? 17.619 34.880 11.535 1.00 42.78 ? 110 ILE B CG1 1 ATOM 4810 C CG2 . ILE B 1 110 ? 17.788 37.267 12.363 1.00 44.31 ? 110 ILE B CG2 1 ATOM 4811 C CD1 . ILE B 1 110 ? 16.202 34.905 11.095 1.00 41.04 ? 110 ILE B CD1 1 ATOM 4812 N N . CYS B 1 111 ? 20.762 34.788 11.603 1.00 46.54 ? 111 CYS B N 1 ATOM 4813 C CA . CYS B 1 111 ? 21.843 34.905 10.602 1.00 48.02 ? 111 CYS B CA 1 ATOM 4814 C C . CYS B 1 111 ? 21.594 33.940 9.427 1.00 48.03 ? 111 CYS B C 1 ATOM 4815 O O . CYS B 1 111 ? 20.699 33.085 9.495 1.00 47.98 ? 111 CYS B O 1 ATOM 4816 C CB . CYS B 1 111 ? 23.206 34.641 11.256 1.00 48.44 ? 111 CYS B CB 1 ATOM 4817 S SG . CYS B 1 111 ? 24.595 34.117 10.176 1.00 53.67 ? 111 CYS B SG 1 ATOM 4818 N N . PHE B 1 112 ? 22.371 34.084 8.354 1.00 47.92 ? 112 PHE B N 1 ATOM 4819 C CA . PHE B 1 112 ? 22.249 33.206 7.187 1.00 48.04 ? 112 PHE B CA 1 ATOM 4820 C C . PHE B 1 112 ? 23.602 32.657 6.750 1.00 48.42 ? 112 PHE B C 1 ATOM 4821 O O . PHE B 1 112 ? 24.572 33.404 6.619 1.00 48.96 ? 112 PHE B O 1 ATOM 4822 C CB . PHE B 1 112 ? 21.554 33.930 6.027 1.00 47.92 ? 112 PHE B CB 1 ATOM 4823 C CG . PHE B 1 112 ? 20.124 34.299 6.318 1.00 47.17 ? 112 PHE B CG 1 ATOM 4824 C CD1 . PHE B 1 112 ? 19.092 33.409 6.044 1.00 47.02 ? 112 PHE B CD1 1 ATOM 4825 C CD2 . PHE B 1 112 ? 19.813 35.528 6.883 1.00 46.64 ? 112 PHE B CD2 1 ATOM 4826 C CE1 . PHE B 1 112 ? 17.765 33.747 6.324 1.00 47.01 ? 112 PHE B CE1 1 ATOM 4827 C CE2 . PHE B 1 112 ? 18.494 35.876 7.174 1.00 47.04 ? 112 PHE B CE2 1 ATOM 4828 C CZ . PHE B 1 112 ? 17.465 34.983 6.888 1.00 47.53 ? 112 PHE B CZ 1 ATOM 4829 N N . THR B 1 113 ? 23.662 31.343 6.545 1.00 48.49 ? 113 THR B N 1 ATOM 4830 C CA . THR B 1 113 ? 24.858 30.681 6.027 1.00 48.18 ? 113 THR B CA 1 ATOM 4831 C C . THR B 1 113 ? 25.187 31.224 4.624 1.00 48.08 ? 113 THR B C 1 ATOM 4832 O O . THR B 1 113 ? 24.332 31.863 4.005 1.00 47.65 ? 113 THR B O 1 ATOM 4833 C CB . THR B 1 113 ? 24.658 29.143 5.956 1.00 48.16 ? 113 THR B CB 1 ATOM 4834 O OG1 . THR B 1 113 ? 23.575 28.835 5.067 1.00 48.13 ? 113 THR B OG1 1 ATOM 4835 C CG2 . THR B 1 113 ? 24.377 28.546 7.349 1.00 48.53 ? 113 THR B CG2 1 ATOM 4836 N N . PRO B 1 114 ? 26.427 30.990 4.130 1.00 48.31 ? 114 PRO B N 1 ATOM 4837 C CA . PRO B 1 114 ? 26.782 31.369 2.753 1.00 48.45 ? 114 PRO B CA 1 ATOM 4838 C C . PRO B 1 114 ? 25.740 30.926 1.718 1.00 48.56 ? 114 PRO B C 1 ATOM 4839 O O . PRO B 1 114 ? 25.413 31.701 0.821 1.00 48.84 ? 114 PRO B O 1 ATOM 4840 C CB . PRO B 1 114 ? 28.105 30.630 2.519 1.00 48.45 ? 114 PRO B CB 1 ATOM 4841 C CG . PRO B 1 114 ? 28.730 30.566 3.867 1.00 48.23 ? 114 PRO B CG 1 ATOM 4842 C CD . PRO B 1 114 ? 27.598 30.455 4.863 1.00 48.27 ? 114 PRO B CD 1 ATOM 4843 N N . ARG B 1 115 ? 25.210 29.710 1.868 1.00 48.23 ? 115 ARG B N 1 ATOM 4844 C CA . ARG B 1 115 ? 24.238 29.152 0.929 1.00 47.95 ? 115 ARG B CA 1 ATOM 4845 C C . ARG B 1 115 ? 22.821 29.680 1.141 1.00 47.43 ? 115 ARG B C 1 ATOM 4846 O O . ARG B 1 115 ? 21.926 29.400 0.335 1.00 47.48 ? 115 ARG B O 1 ATOM 4847 C CB . ARG B 1 115 ? 24.260 27.620 0.972 1.00 48.28 ? 115 ARG B CB 1 ATOM 4848 C CG . ARG B 1 115 ? 25.523 27.011 0.354 1.00 49.32 ? 115 ARG B CG 1 ATOM 4849 C CD . ARG B 1 115 ? 25.525 25.493 0.466 1.00 52.53 ? 115 ARG B CD 1 ATOM 4850 N NE . ARG B 1 115 ? 26.766 24.897 -0.038 1.00 55.00 ? 115 ARG B NE 1 ATOM 4851 C CZ . ARG B 1 115 ? 27.758 24.429 0.725 1.00 56.31 ? 115 ARG B CZ 1 ATOM 4852 N NH1 . ARG B 1 115 ? 27.683 24.477 2.052 1.00 56.24 ? 115 ARG B NH1 1 ATOM 4853 N NH2 . ARG B 1 115 ? 28.837 23.902 0.154 1.00 56.90 ? 115 ARG B NH2 1 ATOM 4854 N N . GLY B 1 116 ? 22.620 30.448 2.210 1.00 46.28 ? 116 GLY B N 1 ATOM 4855 C CA . GLY B 1 116 ? 21.319 31.081 2.468 1.00 45.46 ? 116 GLY B CA 1 ATOM 4856 C C . GLY B 1 116 ? 20.387 30.346 3.430 1.00 44.76 ? 116 GLY B C 1 ATOM 4857 O O . GLY B 1 116 ? 19.177 30.605 3.457 1.00 44.55 ? 116 GLY B O 1 ATOM 4858 N N . ILE B 1 117 ? 20.942 29.434 4.223 1.00 44.10 ? 117 ILE B N 1 ATOM 4859 C CA . ILE B 1 117 ? 20.140 28.724 5.222 1.00 43.64 ? 117 ILE B CA 1 ATOM 4860 C C . ILE B 1 117 ? 20.105 29.458 6.566 1.00 42.90 ? 117 ILE B C 1 ATOM 4861 O O . ILE B 1 117 ? 21.143 29.720 7.182 1.00 42.83 ? 117 ILE B O 1 ATOM 4862 C CB . ILE B 1 117 ? 20.598 27.262 5.417 1.00 43.90 ? 117 ILE B CB 1 ATOM 4863 C CG1 . ILE B 1 117 ? 20.540 26.504 4.078 1.00 44.15 ? 117 ILE B CG1 1 ATOM 4864 C CG2 . ILE B 1 117 ? 19.728 26.574 6.487 1.00 43.38 ? 117 ILE B CG2 1 ATOM 4865 C CD1 . ILE B 1 117 ? 21.337 25.219 4.063 1.00 45.62 ? 117 ILE B CD1 1 ATOM 4866 N N . MET B 1 118 ? 18.889 29.776 6.989 1.00 42.13 ? 118 MET B N 1 ATOM 4867 C CA . MET B 1 118 ? 18.609 30.441 8.258 1.00 41.74 ? 118 MET B CA 1 ATOM 4868 C C . MET B 1 118 ? 19.096 29.677 9.501 1.00 41.01 ? 118 MET B C 1 ATOM 4869 O O . MET B 1 118 ? 19.011 28.454 9.572 1.00 40.19 ? 118 MET B O 1 ATOM 4870 C CB . MET B 1 118 ? 17.116 30.724 8.346 1.00 41.83 ? 118 MET B CB 1 ATOM 4871 C CG . MET B 1 118 ? 16.720 31.655 9.447 1.00 43.33 ? 118 MET B CG 1 ATOM 4872 S SD . MET B 1 118 ? 14.993 32.103 9.285 1.00 48.62 ? 118 MET B SD 1 ATOM 4873 C CE . MET B 1 118 ? 14.176 30.623 9.835 1.00 47.11 ? 118 MET B CE 1 ATOM 4874 N N . GLN B 1 119 ? 19.585 30.441 10.479 1.00 40.71 ? 119 GLN B N 1 ATOM 4875 C CA . GLN B 1 119 ? 20.326 29.947 11.643 1.00 40.20 ? 119 GLN B CA 1 ATOM 4876 C C . GLN B 1 119 ? 20.000 30.872 12.829 1.00 39.34 ? 119 GLN B C 1 ATOM 4877 O O . GLN B 1 119 ? 19.679 32.047 12.626 1.00 38.85 ? 119 GLN B O 1 ATOM 4878 C CB . GLN B 1 119 ? 21.818 30.040 11.329 1.00 40.69 ? 119 GLN B CB 1 ATOM 4879 C CG . GLN B 1 119 ? 22.675 28.936 11.877 1.00 42.74 ? 119 GLN B CG 1 ATOM 4880 C CD . GLN B 1 119 ? 24.132 29.042 11.431 1.00 45.80 ? 119 GLN B CD 1 ATOM 4881 O OE1 . GLN B 1 119 ? 24.481 29.987 10.690 1.00 47.41 ? 119 GLN B OE1 1 ATOM 4882 N NE2 . GLN B 1 119 ? 24.944 28.172 11.818 1.00 48.56 ? 119 GLN B NE2 1 ATOM 4883 N N . PHE B 1 120 ? 20.053 30.341 14.056 1.00 38.24 ? 120 PHE B N 1 ATOM 4884 C CA . PHE B 1 120 ? 19.794 31.142 15.264 1.00 37.20 ? 120 PHE B CA 1 ATOM 4885 C C . PHE B 1 120 ? 20.814 30.881 16.360 1.00 36.85 ? 120 PHE B C 1 ATOM 4886 O O . PHE B 1 120 ? 21.346 29.778 16.478 1.00 36.22 ? 120 PHE B O 1 ATOM 4887 C CB . PHE B 1 120 ? 18.392 30.895 15.833 1.00 36.71 ? 120 PHE B CB 1 ATOM 4888 C CG . PHE B 1 120 ? 17.279 31.356 14.949 1.00 36.48 ? 120 PHE B CG 1 ATOM 4889 C CD1 . PHE B 1 120 ? 16.755 32.642 15.079 1.00 35.83 ? 120 PHE B CD1 1 ATOM 4890 C CD2 . PHE B 1 120 ? 16.732 30.503 13.982 1.00 35.67 ? 120 PHE B CD2 1 ATOM 4891 C CE1 . PHE B 1 120 ? 15.714 33.076 14.274 1.00 33.69 ? 120 PHE B CE1 1 ATOM 4892 C CE2 . PHE B 1 120 ? 15.683 30.938 13.146 1.00 34.09 ? 120 PHE B CE2 1 ATOM 4893 C CZ . PHE B 1 120 ? 15.169 32.217 13.302 1.00 35.57 ? 120 PHE B CZ 1 ATOM 4894 N N . ARG B 1 121 ? 21.079 31.915 17.157 1.00 37.07 ? 121 ARG B N 1 ATOM 4895 C CA . ARG B 1 121 ? 21.912 31.793 18.350 1.00 37.11 ? 121 ARG B CA 1 ATOM 4896 C C . ARG B 1 121 ? 21.489 32.808 19.407 1.00 36.77 ? 121 ARG B C 1 ATOM 4897 O O . ARG B 1 121 ? 21.247 33.984 19.112 1.00 35.59 ? 121 ARG B O 1 ATOM 4898 C CB . ARG B 1 121 ? 23.396 31.943 18.022 1.00 37.71 ? 121 ARG B CB 1 ATOM 4899 C CG . ARG B 1 121 ? 24.303 31.310 19.068 1.00 40.81 ? 121 ARG B CG 1 ATOM 4900 C CD . ARG B 1 121 ? 25.758 31.718 18.896 1.00 46.61 ? 121 ARG B CD 1 ATOM 4901 N NE . ARG B 1 121 ? 26.425 31.005 17.800 1.00 51.26 ? 121 ARG B NE 1 ATOM 4902 C CZ . ARG B 1 121 ? 27.737 31.039 17.555 1.00 52.17 ? 121 ARG B CZ 1 ATOM 4903 N NH1 . ARG B 1 121 ? 28.556 31.756 18.325 1.00 52.70 ? 121 ARG B NH1 1 ATOM 4904 N NH2 . ARG B 1 121 ? 28.234 30.351 16.536 1.00 51.94 ? 121 ARG B NH2 1 ATOM 4905 N N . PHE B 1 122 ? 21.358 32.327 20.640 1.00 36.81 ? 122 PHE B N 1 ATOM 4906 C CA . PHE B 1 122 ? 21.158 33.206 21.790 1.00 36.93 ? 122 PHE B CA 1 ATOM 4907 C C . PHE B 1 122 ? 22.527 33.518 22.329 1.00 37.46 ? 122 PHE B C 1 ATOM 4908 O O . PHE B 1 122 ? 23.315 32.607 22.586 1.00 37.26 ? 122 PHE B O 1 ATOM 4909 C CB . PHE B 1 122 ? 20.330 32.529 22.878 1.00 36.34 ? 122 PHE B CB 1 ATOM 4910 C CG . PHE B 1 122 ? 18.856 32.618 22.663 1.00 35.83 ? 122 PHE B CG 1 ATOM 4911 C CD1 . PHE B 1 122 ? 18.188 31.638 21.939 1.00 34.14 ? 122 PHE B CD1 1 ATOM 4912 C CD2 . PHE B 1 122 ? 18.128 33.681 23.196 1.00 34.70 ? 122 PHE B CD2 1 ATOM 4913 C CE1 . PHE B 1 122 ? 16.814 31.708 21.759 1.00 34.52 ? 122 PHE B CE1 1 ATOM 4914 C CE2 . PHE B 1 122 ? 16.764 33.766 23.014 1.00 35.93 ? 122 PHE B CE2 1 ATOM 4915 C CZ . PHE B 1 122 ? 16.096 32.770 22.289 1.00 34.82 ? 122 PHE B CZ 1 ATOM 4916 N N . ALA B 1 123 ? 22.828 34.806 22.465 1.00 38.63 ? 123 ALA B N 1 ATOM 4917 C CA . ALA B 1 123 ? 24.150 35.223 22.917 1.00 39.89 ? 123 ALA B CA 1 ATOM 4918 C C . ALA B 1 123 ? 24.173 36.655 23.451 1.00 41.21 ? 123 ALA B C 1 ATOM 4919 O O . ALA B 1 123 ? 23.433 37.532 22.987 1.00 40.75 ? 123 ALA B O 1 ATOM 4920 C CB . ALA B 1 123 ? 25.193 35.040 21.802 1.00 39.36 ? 123 ALA B CB 1 ATOM 4921 N N . HIS B 1 124 ? 25.014 36.859 24.461 1.00 43.15 ? 124 HIS B N 1 ATOM 4922 C CA . HIS B 1 124 ? 25.363 38.190 24.929 1.00 45.15 ? 124 HIS B CA 1 ATOM 4923 C C . HIS B 1 124 ? 26.794 38.186 25.430 1.00 45.87 ? 124 HIS B C 1 ATOM 4924 O O . HIS B 1 124 ? 27.111 37.446 26.363 1.00 45.92 ? 124 HIS B O 1 ATOM 4925 C CB . HIS B 1 124 ? 24.420 38.695 26.015 1.00 45.40 ? 124 HIS B CB 1 ATOM 4926 C CG . HIS B 1 124 ? 24.696 40.107 26.416 1.00 47.62 ? 124 HIS B CG 1 ATOM 4927 N ND1 . HIS B 1 124 ? 23.906 41.163 26.018 1.00 49.88 ? 124 HIS B ND1 1 ATOM 4928 C CD2 . HIS B 1 124 ? 25.704 40.644 27.145 1.00 48.60 ? 124 HIS B CD2 1 ATOM 4929 C CE1 . HIS B 1 124 ? 24.396 42.286 26.508 1.00 50.12 ? 124 HIS B CE1 1 ATOM 4930 N NE2 . HIS B 1 124 ? 25.487 41.998 27.196 1.00 48.92 ? 124 HIS B NE2 1 ATOM 4931 N N . PRO B 1 125 ? 27.661 39.010 24.805 1.00 46.89 ? 125 PRO B N 1 ATOM 4932 C CA . PRO B 1 125 ? 27.306 39.927 23.702 1.00 47.58 ? 125 PRO B CA 1 ATOM 4933 C C . PRO B 1 125 ? 27.213 39.236 22.322 1.00 48.47 ? 125 PRO B C 1 ATOM 4934 O O . PRO B 1 125 ? 27.567 38.060 22.198 1.00 48.20 ? 125 PRO B O 1 ATOM 4935 C CB . PRO B 1 125 ? 28.461 40.932 23.715 1.00 47.27 ? 125 PRO B CB 1 ATOM 4936 C CG . PRO B 1 125 ? 29.636 40.121 24.133 1.00 47.29 ? 125 PRO B CG 1 ATOM 4937 C CD . PRO B 1 125 ? 29.092 39.115 25.156 1.00 47.02 ? 125 PRO B CD 1 ATOM 4938 N N . THR B 1 126 ? 26.722 39.965 21.313 1.00 49.37 ? 126 THR B N 1 ATOM 4939 C CA . THR B 1 126 ? 26.674 39.486 19.920 1.00 50.29 ? 126 THR B CA 1 ATOM 4940 C C . THR B 1 126 ? 27.994 38.829 19.515 1.00 51.50 ? 126 THR B C 1 ATOM 4941 O O . THR B 1 126 ? 29.036 39.451 19.639 1.00 51.50 ? 126 THR B O 1 ATOM 4942 C CB . THR B 1 126 ? 26.401 40.662 18.954 1.00 50.04 ? 126 THR B CB 1 ATOM 4943 O OG1 . THR B 1 126 ? 25.158 41.283 19.296 1.00 49.11 ? 126 THR B OG1 1 ATOM 4944 C CG2 . THR B 1 126 ? 26.370 40.200 17.487 1.00 49.80 ? 126 THR B CG2 1 ATOM 4945 N N . PRO B 1 127 ? 27.953 37.568 19.034 1.00 53.04 ? 127 PRO B N 1 ATOM 4946 C CA . PRO B 1 127 ? 29.184 36.856 18.672 1.00 54.39 ? 127 PRO B CA 1 ATOM 4947 C C . PRO B 1 127 ? 29.878 37.402 17.423 1.00 55.83 ? 127 PRO B C 1 ATOM 4948 O O . PRO B 1 127 ? 29.242 38.028 16.571 1.00 55.77 ? 127 PRO B O 1 ATOM 4949 C CB . PRO B 1 127 ? 28.710 35.417 18.418 1.00 54.32 ? 127 PRO B CB 1 ATOM 4950 C CG . PRO B 1 127 ? 27.346 35.343 18.978 1.00 53.52 ? 127 PRO B CG 1 ATOM 4951 C CD . PRO B 1 127 ? 26.770 36.709 18.867 1.00 53.19 ? 127 PRO B CD 1 ATOM 4952 N N . ARG B 1 128 ? 31.184 37.153 17.342 1.00 57.71 ? 128 ARG B N 1 ATOM 4953 C CA . ARG B 1 128 ? 32.018 37.574 16.219 1.00 59.64 ? 128 ARG B CA 1 ATOM 4954 C C . ARG B 1 128 ? 31.640 36.844 14.928 1.00 60.37 ? 128 ARG B C 1 ATOM 4955 O O . ARG B 1 128 ? 31.173 35.703 14.978 1.00 60.52 ? 128 ARG B O 1 ATOM 4956 C CB . ARG B 1 128 ? 33.493 37.305 16.535 1.00 60.08 ? 128 ARG B CB 1 ATOM 4957 C CG . ARG B 1 128 ? 34.250 38.455 17.185 1.00 61.63 ? 128 ARG B CG 1 ATOM 4958 C CD . ARG B 1 128 ? 35.761 38.228 17.027 1.00 64.58 ? 128 ARG B CD 1 ATOM 4959 N NE . ARG B 1 128 ? 36.458 39.413 16.516 1.00 66.67 ? 128 ARG B NE 1 ATOM 4960 C CZ . ARG B 1 128 ? 36.463 39.804 15.238 1.00 67.73 ? 128 ARG B CZ 1 ATOM 4961 N NH1 . ARG B 1 128 ? 35.803 39.116 14.309 1.00 67.97 ? 128 ARG B NH1 1 ATOM 4962 N NH2 . ARG B 1 128 ? 37.129 40.898 14.885 1.00 68.06 ? 128 ARG B NH2 1 ATOM 4963 N N . PRO B 1 129 ? 31.823 37.507 13.767 1.00 61.11 ? 129 PRO B N 1 ATOM 4964 C CA . PRO B 1 129 ? 31.681 36.838 12.473 1.00 61.56 ? 129 PRO B CA 1 ATOM 4965 C C . PRO B 1 129 ? 32.557 35.595 12.384 1.00 61.93 ? 129 PRO B C 1 ATOM 4966 O O . PRO B 1 129 ? 33.728 35.648 12.755 1.00 62.19 ? 129 PRO B O 1 ATOM 4967 C CB . PRO B 1 129 ? 32.169 37.899 11.487 1.00 61.58 ? 129 PRO B CB 1 ATOM 4968 C CG . PRO B 1 129 ? 31.777 39.183 12.132 1.00 61.38 ? 129 PRO B CG 1 ATOM 4969 C CD . PRO B 1 129 ? 31.967 38.969 13.611 1.00 61.12 ? 129 PRO B CD 1 ATOM 4970 N N . SER B 1 130 ? 31.980 34.487 11.920 1.00 62.36 ? 130 SER B N 1 ATOM 4971 C CA . SER B 1 130 ? 32.715 33.233 11.732 1.00 62.63 ? 130 SER B CA 1 ATOM 4972 C C . SER B 1 130 ? 32.587 32.705 10.295 1.00 62.98 ? 130 SER B C 1 ATOM 4973 O O . SER B 1 130 ? 32.047 33.382 9.414 1.00 62.75 ? 130 SER B O 1 ATOM 4974 C CB . SER B 1 130 ? 32.241 32.180 12.735 1.00 62.54 ? 130 SER B CB 1 ATOM 4975 O OG . SER B 1 130 ? 30.904 31.809 12.474 1.00 62.71 ? 130 SER B OG 1 ATOM 4976 N N . GLU B 1 131 ? 33.083 31.492 10.069 1.00 63.44 ? 131 GLU B N 1 ATOM 4977 C CA . GLU B 1 131 ? 33.065 30.888 8.736 1.00 63.97 ? 131 GLU B CA 1 ATOM 4978 C C . GLU B 1 131 ? 31.678 30.396 8.310 1.00 63.72 ? 131 GLU B C 1 ATOM 4979 O O . GLU B 1 131 ? 31.355 30.407 7.120 1.00 64.13 ? 131 GLU B O 1 ATOM 4980 C CB . GLU B 1 131 ? 34.100 29.767 8.644 1.00 64.14 ? 131 GLU B CB 1 ATOM 4981 C CG . GLU B 1 131 ? 35.522 30.283 8.730 1.00 65.78 ? 131 GLU B CG 1 ATOM 4982 C CD . GLU B 1 131 ? 36.516 29.190 9.022 1.00 68.17 ? 131 GLU B CD 1 ATOM 4983 O OE1 . GLU B 1 131 ? 36.844 28.421 8.089 1.00 69.59 ? 131 GLU B OE1 1 ATOM 4984 O OE2 . GLU B 1 131 ? 36.974 29.105 10.185 1.00 69.39 ? 131 GLU B OE2 1 ATOM 4985 N N . LYS B 1 132 ? 30.869 29.967 9.277 1.00 63.27 ? 132 LYS B N 1 ATOM 4986 C CA . LYS B 1 132 ? 29.495 29.544 9.002 1.00 62.75 ? 132 LYS B CA 1 ATOM 4987 C C . LYS B 1 132 ? 28.504 30.713 9.048 1.00 61.92 ? 132 LYS B C 1 ATOM 4988 O O . LYS B 1 132 ? 27.373 30.590 8.567 1.00 61.87 ? 132 LYS B O 1 ATOM 4989 C CB . LYS B 1 132 ? 29.066 28.434 9.968 1.00 63.09 ? 132 LYS B CB 1 ATOM 4990 C CG . LYS B 1 132 ? 29.808 27.101 9.787 1.00 64.09 ? 132 LYS B CG 1 ATOM 4991 C CD . LYS B 1 132 ? 29.088 26.165 8.813 1.00 65.68 ? 132 LYS B CD 1 ATOM 4992 C CE . LYS B 1 132 ? 29.616 24.734 8.936 1.00 66.14 ? 132 LYS B CE 1 ATOM 4993 N NZ . LYS B 1 132 ? 28.819 23.771 8.118 1.00 66.76 ? 132 LYS B NZ 1 ATOM 4994 N N . CYS B 1 133 ? 28.934 31.836 9.628 1.00 60.92 ? 133 CYS B N 1 ATOM 4995 C CA . CYS B 1 133 ? 28.107 33.048 9.721 1.00 59.90 ? 133 CYS B CA 1 ATOM 4996 C C . CYS B 1 133 ? 28.958 34.304 9.612 1.00 59.85 ? 133 CYS B C 1 ATOM 4997 O O . CYS B 1 133 ? 29.952 34.446 10.324 1.00 60.13 ? 133 CYS B O 1 ATOM 4998 C CB . CYS B 1 133 ? 27.317 33.088 11.036 1.00 59.49 ? 133 CYS B CB 1 ATOM 4999 S SG . CYS B 1 133 ? 26.280 34.576 11.232 1.00 56.99 ? 133 CYS B SG 1 ATOM 5000 N N . SER B 1 134 ? 28.549 35.222 8.743 1.00 59.20 ? 134 SER B N 1 ATOM 5001 C CA . SER B 1 134 ? 29.325 36.433 8.491 1.00 58.78 ? 134 SER B CA 1 ATOM 5002 C C . SER B 1 134 ? 28.805 37.623 9.297 1.00 58.29 ? 134 SER B C 1 ATOM 5003 O O . SER B 1 134 ? 29.556 38.564 9.563 1.00 58.22 ? 134 SER B O 1 ATOM 5004 C CB . SER B 1 134 ? 29.330 36.765 6.998 1.00 58.86 ? 134 SER B CB 1 ATOM 5005 O OG . SER B 1 134 ? 28.052 37.216 6.583 1.00 58.72 ? 134 SER B OG 1 ATOM 5006 N N . LYS B 1 135 ? 27.523 37.582 9.668 1.00 57.60 ? 135 LYS B N 1 ATOM 5007 C CA . LYS B 1 135 ? 26.946 38.589 10.563 1.00 56.89 ? 135 LYS B CA 1 ATOM 5008 C C . LYS B 1 135 ? 25.736 38.107 11.375 1.00 56.05 ? 135 LYS B C 1 ATOM 5009 O O . LYS B 1 135 ? 24.644 37.908 10.833 1.00 55.85 ? 135 LYS B O 1 ATOM 5010 C CB . LYS B 1 135 ? 26.594 39.881 9.808 1.00 57.16 ? 135 LYS B CB 1 ATOM 5011 C CG . LYS B 1 135 ? 26.300 41.055 10.741 1.00 58.11 ? 135 LYS B CG 1 ATOM 5012 C CD . LYS B 1 135 ? 25.630 42.210 10.029 1.00 60.60 ? 135 LYS B CD 1 ATOM 5013 C CE . LYS B 1 135 ? 25.423 43.382 10.981 1.00 61.84 ? 135 LYS B CE 1 ATOM 5014 N NZ . LYS B 1 135 ? 24.436 44.370 10.441 1.00 63.30 ? 135 LYS B NZ 1 ATOM 5015 N N . TRP B 1 136 ? 25.940 37.927 12.678 1.00 54.83 ? 136 TRP B N 1 ATOM 5016 C CA . TRP B 1 136 ? 24.826 37.700 13.584 1.00 53.84 ? 136 TRP B CA 1 ATOM 5017 C C . TRP B 1 136 ? 24.137 39.024 13.843 1.00 54.11 ? 136 TRP B C 1 ATOM 5018 O O . TRP B 1 136 ? 24.786 40.014 14.178 1.00 54.19 ? 136 TRP B O 1 ATOM 5019 C CB . TRP B 1 136 ? 25.286 37.071 14.901 1.00 53.09 ? 136 TRP B CB 1 ATOM 5020 C CG . TRP B 1 136 ? 25.685 35.648 14.775 1.00 50.48 ? 136 TRP B CG 1 ATOM 5021 C CD1 . TRP B 1 136 ? 26.951 35.160 14.772 1.00 48.96 ? 136 TRP B CD1 1 ATOM 5022 C CD2 . TRP B 1 136 ? 24.813 34.516 14.633 1.00 47.98 ? 136 TRP B CD2 1 ATOM 5023 N NE1 . TRP B 1 136 ? 26.932 33.796 14.639 1.00 48.93 ? 136 TRP B NE1 1 ATOM 5024 C CE2 . TRP B 1 136 ? 25.631 33.373 14.550 1.00 48.19 ? 136 TRP B CE2 1 ATOM 5025 C CE3 . TRP B 1 136 ? 23.421 34.359 14.573 1.00 47.06 ? 136 TRP B CE3 1 ATOM 5026 C CZ2 . TRP B 1 136 ? 25.108 32.081 14.400 1.00 46.87 ? 136 TRP B CZ2 1 ATOM 5027 C CZ3 . TRP B 1 136 ? 22.899 33.075 14.417 1.00 45.94 ? 136 TRP B CZ3 1 ATOM 5028 C CH2 . TRP B 1 136 ? 23.744 31.955 14.336 1.00 45.99 ? 136 TRP B CH2 1 ATOM 5029 N N . ILE B 1 137 ? 22.821 39.034 13.665 1.00 54.34 ? 137 ILE B N 1 ATOM 5030 C CA . ILE B 1 137 ? 22.007 40.225 13.852 1.00 54.95 ? 137 ILE B CA 1 ATOM 5031 C C . ILE B 1 137 ? 20.919 39.926 14.877 1.00 55.54 ? 137 ILE B C 1 ATOM 5032 O O . ILE B 1 137 ? 20.232 38.905 14.783 1.00 55.28 ? 137 ILE B O 1 ATOM 5033 C CB . ILE B 1 137 ? 21.361 40.678 12.516 1.00 55.03 ? 137 ILE B CB 1 ATOM 5034 C CG1 . ILE B 1 137 ? 22.446 40.976 11.472 1.00 54.95 ? 137 ILE B CG1 1 ATOM 5035 C CG2 . ILE B 1 137 ? 20.443 41.899 12.727 1.00 54.92 ? 137 ILE B CG2 1 ATOM 5036 C CD1 . ILE B 1 137 ? 21.950 40.987 10.039 1.00 55.20 ? 137 ILE B CD1 1 ATOM 5037 N N . LEU B 1 138 ? 20.773 40.819 15.853 1.00 56.32 ? 138 LEU B N 1 ATOM 5038 C CA . LEU B 1 138 ? 19.772 40.691 16.906 1.00 57.26 ? 138 LEU B CA 1 ATOM 5039 C C . LEU B 1 138 ? 18.358 40.779 16.331 1.00 57.95 ? 138 LEU B C 1 ATOM 5040 O O . LEU B 1 138 ? 18.080 41.655 15.509 1.00 57.96 ? 138 LEU B O 1 ATOM 5041 C CB . LEU B 1 138 ? 19.997 41.783 17.958 1.00 57.37 ? 138 LEU B CB 1 ATOM 5042 C CG . LEU B 1 138 ? 19.393 41.613 19.353 1.00 57.56 ? 138 LEU B CG 1 ATOM 5043 C CD1 . LEU B 1 138 ? 20.001 40.424 20.067 1.00 57.45 ? 138 LEU B CD1 1 ATOM 5044 C CD2 . LEU B 1 138 ? 19.596 42.882 20.166 1.00 58.20 ? 138 LEU B CD2 1 ATOM 5045 N N . LEU B 1 139 ? 17.478 39.866 16.746 1.00 58.76 ? 139 LEU B N 1 ATOM 5046 C CA . LEU B 1 139 ? 16.087 39.852 16.266 1.00 59.75 ? 139 LEU B CA 1 ATOM 5047 C C . LEU B 1 139 ? 15.341 41.162 16.503 1.00 60.63 ? 139 LEU B C 1 ATOM 5048 O O . LEU B 1 139 ? 14.553 41.571 15.657 1.00 60.88 ? 139 LEU B O 1 ATOM 5049 C CB . LEU B 1 139 ? 15.275 38.679 16.854 1.00 59.64 ? 139 LEU B CB 1 ATOM 5050 C CG . LEU B 1 139 ? 15.006 37.375 16.075 1.00 58.67 ? 139 LEU B CG 1 ATOM 5051 C CD1 . LEU B 1 139 ? 14.317 37.612 14.734 1.00 58.07 ? 139 LEU B CD1 1 ATOM 5052 C CD2 . LEU B 1 139 ? 16.273 36.581 15.880 1.00 57.89 ? 139 LEU B CD2 1 ATOM 5053 N N . GLU B 1 140 ? 15.576 41.808 17.645 1.00 61.96 ? 140 GLU B N 1 ATOM 5054 C CA . GLU B 1 140 ? 14.905 43.081 17.959 1.00 63.17 ? 140 GLU B CA 1 ATOM 5055 C C . GLU B 1 140 ? 15.264 44.188 16.963 1.00 63.58 ? 140 GLU B C 1 ATOM 5056 O O . GLU B 1 140 ? 14.404 44.980 16.574 1.00 63.62 ? 140 GLU B O 1 ATOM 5057 C CB . GLU B 1 140 ? 15.164 43.516 19.407 1.00 63.26 ? 140 GLU B CB 1 ATOM 5058 C CG . GLU B 1 140 ? 14.137 42.940 20.392 1.00 64.94 ? 140 GLU B CG 1 ATOM 5059 C CD . GLU B 1 140 ? 14.470 43.215 21.856 1.00 67.11 ? 140 GLU B CD 1 ATOM 5060 O OE1 . GLU B 1 140 ? 14.370 44.389 22.285 1.00 67.06 ? 140 GLU B OE1 1 ATOM 5061 O OE2 . GLU B 1 140 ? 14.813 42.248 22.581 1.00 67.48 ? 140 GLU B OE2 1 ATOM 5062 N N . ASP B 1 141 ? 16.528 44.215 16.544 1.00 64.33 ? 141 ASP B N 1 ATOM 5063 C CA . ASP B 1 141 ? 16.990 45.111 15.481 1.00 65.02 ? 141 ASP B CA 1 ATOM 5064 C C . ASP B 1 141 ? 16.332 44.780 14.146 1.00 65.62 ? 141 ASP B C 1 ATOM 5065 O O . ASP B 1 141 ? 15.687 45.638 13.533 1.00 65.81 ? 141 ASP B O 1 ATOM 5066 C CB . ASP B 1 141 ? 18.517 45.045 15.347 1.00 64.85 ? 141 ASP B CB 1 ATOM 5067 C CG . ASP B 1 141 ? 19.238 45.651 16.541 1.00 64.67 ? 141 ASP B CG 1 ATOM 5068 O OD1 . ASP B 1 141 ? 18.560 46.076 17.503 1.00 63.43 ? 141 ASP B OD1 1 ATOM 5069 O OD2 . ASP B 1 141 ? 20.486 45.698 16.514 1.00 64.07 ? 141 ASP B OD2 1 ATOM 5070 N N . TYR B 1 142 ? 16.491 43.527 13.718 1.00 66.25 ? 142 TYR B N 1 ATOM 5071 C CA . TYR B 1 142 ? 15.950 43.022 12.460 1.00 66.82 ? 142 TYR B CA 1 ATOM 5072 C C . TYR B 1 142 ? 14.449 43.254 12.322 1.00 67.48 ? 142 TYR B C 1 ATOM 5073 O O . TYR B 1 142 ? 13.951 43.399 11.206 1.00 67.70 ? 142 TYR B O 1 ATOM 5074 C CB . TYR B 1 142 ? 16.216 41.522 12.371 1.00 66.71 ? 142 TYR B CB 1 ATOM 5075 C CG . TYR B 1 142 ? 16.453 40.968 10.978 1.00 66.35 ? 142 TYR B CG 1 ATOM 5076 C CD1 . TYR B 1 142 ? 17.746 40.680 10.538 1.00 65.92 ? 142 TYR B CD1 1 ATOM 5077 C CD2 . TYR B 1 142 ? 15.387 40.699 10.114 1.00 66.05 ? 142 TYR B CD2 1 ATOM 5078 C CE1 . TYR B 1 142 ? 17.977 40.155 9.271 1.00 66.54 ? 142 TYR B CE1 1 ATOM 5079 C CE2 . TYR B 1 142 ? 15.606 40.175 8.837 1.00 66.27 ? 142 TYR B CE2 1 ATOM 5080 C CZ . TYR B 1 142 ? 16.904 39.906 8.424 1.00 66.64 ? 142 TYR B CZ 1 ATOM 5081 O OH . TYR B 1 142 ? 17.138 39.386 7.170 1.00 67.21 ? 142 TYR B OH 1 ATOM 5082 N N . ARG B 1 143 ? 13.739 43.292 13.449 1.00 68.20 ? 143 ARG B N 1 ATOM 5083 C CA . ARG B 1 143 ? 12.269 43.285 13.442 1.00 69.14 ? 143 ARG B CA 1 ATOM 5084 C C . ARG B 1 143 ? 11.570 44.571 13.003 1.00 69.75 ? 143 ARG B C 1 ATOM 5085 O O . ARG B 1 143 ? 10.512 44.508 12.372 1.00 69.96 ? 143 ARG B O 1 ATOM 5086 C CB . ARG B 1 143 ? 11.701 42.820 14.785 1.00 69.01 ? 143 ARG B CB 1 ATOM 5087 C CG . ARG B 1 143 ? 11.535 41.315 14.858 1.00 69.61 ? 143 ARG B CG 1 ATOM 5088 C CD . ARG B 1 143 ? 10.548 40.881 15.928 1.00 69.27 ? 143 ARG B CD 1 ATOM 5089 N NE . ARG B 1 143 ? 10.020 39.555 15.612 1.00 69.42 ? 143 ARG B NE 1 ATOM 5090 C CZ . ARG B 1 143 ? 10.554 38.400 16.010 1.00 68.98 ? 143 ARG B CZ 1 ATOM 5091 N NH1 . ARG B 1 143 ? 11.643 38.373 16.770 1.00 68.07 ? 143 ARG B NH1 1 ATOM 5092 N NH2 . ARG B 1 143 ? 9.985 37.262 15.643 1.00 68.44 ? 143 ARG B NH2 1 ATOM 5093 N N . LYS B 1 144 ? 12.136 45.726 13.341 1.00 70.50 ? 144 LYS B N 1 ATOM 5094 C CA . LYS B 1 144 ? 11.511 47.007 12.977 1.00 71.04 ? 144 LYS B CA 1 ATOM 5095 C C . LYS B 1 144 ? 11.782 47.382 11.516 1.00 71.47 ? 144 LYS B C 1 ATOM 5096 O O . LYS B 1 144 ? 10.951 48.031 10.874 1.00 71.57 ? 144 LYS B O 1 ATOM 5097 C CB . LYS B 1 144 ? 11.960 48.121 13.923 1.00 71.12 ? 144 LYS B CB 1 ATOM 5098 C CG . LYS B 1 144 ? 11.663 47.847 15.395 1.00 70.59 ? 144 LYS B CG 1 ATOM 5099 C CD . LYS B 1 144 ? 12.758 48.422 16.272 1.00 70.27 ? 144 LYS B CD 1 ATOM 5100 C CE . LYS B 1 144 ? 12.584 48.016 17.721 1.00 69.89 ? 144 LYS B CE 1 ATOM 5101 N NZ . LYS B 1 144 ? 13.768 48.430 18.512 1.00 69.03 ? 144 LYS B NZ 1 ATOM 5102 N N . ARG B 1 145 ? 12.933 46.941 10.999 1.00 71.93 ? 145 ARG B N 1 ATOM 5103 C CA . ARG B 1 145 ? 13.355 47.186 9.612 1.00 72.27 ? 145 ARG B CA 1 ATOM 5104 C C . ARG B 1 145 ? 12.383 46.690 8.528 1.00 72.66 ? 145 ARG B C 1 ATOM 5105 O O . ARG B 1 145 ? 12.383 47.201 7.403 1.00 72.75 ? 145 ARG B O 1 ATOM 5106 C CB . ARG B 1 145 ? 14.733 46.579 9.365 1.00 72.04 ? 145 ARG B CB 1 ATOM 5107 C CG . ARG B 1 145 ? 15.836 47.199 10.187 1.00 72.35 ? 145 ARG B CG 1 ATOM 5108 C CD . ARG B 1 145 ? 17.178 46.620 9.789 1.00 72.89 ? 145 ARG B CD 1 ATOM 5109 N NE . ARG B 1 145 ? 18.154 46.746 10.867 1.00 73.50 ? 145 ARG B NE 1 ATOM 5110 C CZ . ARG B 1 145 ? 19.276 46.038 10.954 1.00 73.70 ? 145 ARG B CZ 1 ATOM 5111 N NH1 . ARG B 1 145 ? 19.581 45.143 10.019 1.00 73.81 ? 145 ARG B NH1 1 ATOM 5112 N NH2 . ARG B 1 145 ? 20.097 46.226 11.980 1.00 73.43 ? 145 ARG B NH2 1 ATOM 5113 N N . VAL B 1 146 ? 11.568 45.692 8.857 1.00 72.96 ? 146 VAL B N 1 ATOM 5114 C CA . VAL B 1 146 ? 10.609 45.144 7.895 1.00 73.32 ? 146 VAL B CA 1 ATOM 5115 C C . VAL B 1 146 ? 9.311 45.975 7.873 1.00 73.53 ? 146 VAL B C 1 ATOM 5116 O O . VAL B 1 146 ? 8.915 46.547 8.898 1.00 73.66 ? 146 VAL B O 1 ATOM 5117 C CB . VAL B 1 146 ? 10.345 43.619 8.140 1.00 73.41 ? 146 VAL B CB 1 ATOM 5118 C CG1 . VAL B 1 146 ? 11.670 42.875 8.356 1.00 73.14 ? 146 VAL B CG1 1 ATOM 5119 C CG2 . VAL B 1 146 ? 9.393 43.383 9.318 1.00 73.22 ? 146 VAL B CG2 1 ATOM 5120 N N . GLN B 1 147 ? 8.666 46.055 6.709 1.00 73.60 ? 147 GLN B N 1 ATOM 5121 C CA . GLN B 1 147 ? 7.459 46.884 6.558 1.00 73.73 ? 147 GLN B CA 1 ATOM 5122 C C . GLN B 1 147 ? 6.166 46.222 7.067 1.00 73.46 ? 147 GLN B C 1 ATOM 5123 O O . GLN B 1 147 ? 5.125 46.885 7.190 1.00 73.63 ? 147 GLN B O 1 ATOM 5124 C CB . GLN B 1 147 ? 7.310 47.416 5.118 1.00 73.98 ? 147 GLN B CB 1 ATOM 5125 C CG . GLN B 1 147 ? 7.833 48.861 4.942 1.00 74.68 ? 147 GLN B CG 1 ATOM 5126 C CD . GLN B 1 147 ? 7.660 49.420 3.529 1.00 75.52 ? 147 GLN B CD 1 ATOM 5127 O OE1 . GLN B 1 147 ? 8.102 48.813 2.544 1.00 76.14 ? 147 GLN B OE1 1 ATOM 5128 N NE2 . GLN B 1 147 ? 7.031 50.594 3.427 1.00 74.81 ? 147 GLN B NE2 1 ATOM 5129 N N . ASN B 1 148 ? 6.245 44.923 7.360 1.00 72.99 ? 148 ASN B N 1 ATOM 5130 C CA . ASN B 1 148 ? 5.170 44.190 8.038 1.00 72.33 ? 148 ASN B CA 1 ATOM 5131 C C . ASN B 1 148 ? 5.770 43.102 8.941 1.00 71.77 ? 148 ASN B C 1 ATOM 5132 O O . ASN B 1 148 ? 6.224 42.056 8.462 1.00 71.73 ? 148 ASN B O 1 ATOM 5133 C CB . ASN B 1 148 ? 4.167 43.605 7.024 1.00 72.43 ? 148 ASN B CB 1 ATOM 5134 C CG . ASN B 1 148 ? 2.801 43.297 7.646 1.00 72.64 ? 148 ASN B CG 1 ATOM 5135 O OD1 . ASN B 1 148 ? 2.665 43.181 8.865 1.00 73.19 ? 148 ASN B OD1 1 ATOM 5136 N ND2 . ASN B 1 148 ? 1.784 43.161 6.800 1.00 72.60 ? 148 ASN B ND2 1 ATOM 5137 N N . VAL B 1 149 ? 5.795 43.373 10.246 1.00 70.94 ? 149 VAL B N 1 ATOM 5138 C CA . VAL B 1 149 ? 6.402 42.459 11.223 1.00 69.92 ? 149 VAL B CA 1 ATOM 5139 C C . VAL B 1 149 ? 5.579 41.177 11.375 1.00 69.11 ? 149 VAL B C 1 ATOM 5140 O O . VAL B 1 149 ? 6.135 40.106 11.640 1.00 69.20 ? 149 VAL B O 1 ATOM 5141 C CB . VAL B 1 149 ? 6.675 43.154 12.600 1.00 70.07 ? 149 VAL B CB 1 ATOM 5142 C CG1 . VAL B 1 149 ? 5.373 43.485 13.345 1.00 70.10 ? 149 VAL B CG1 1 ATOM 5143 C CG2 . VAL B 1 149 ? 7.612 42.314 13.470 1.00 69.94 ? 149 VAL B CG2 1 ATOM 5144 N N . THR B 1 150 ? 4.265 41.290 11.180 1.00 67.83 ? 150 THR B N 1 ATOM 5145 C CA . THR B 1 150 ? 3.378 40.128 11.182 1.00 66.61 ? 150 THR B CA 1 ATOM 5146 C C . THR B 1 150 ? 3.730 39.214 10.013 1.00 65.54 ? 150 THR B C 1 ATOM 5147 O O . THR B 1 150 ? 3.583 37.995 10.103 1.00 65.63 ? 150 THR B O 1 ATOM 5148 C CB . THR B 1 150 ? 1.895 40.528 11.055 1.00 66.66 ? 150 THR B CB 1 ATOM 5149 O OG1 . THR B 1 150 ? 1.699 41.843 11.588 1.00 67.10 ? 150 THR B OG1 1 ATOM 5150 C CG2 . THR B 1 150 ? 0.999 39.527 11.786 1.00 66.34 ? 150 THR B CG2 1 ATOM 5151 N N . GLU B 1 151 ? 4.202 39.814 8.923 1.00 63.99 ? 151 GLU B N 1 ATOM 5152 C CA . GLU B 1 151 ? 4.583 39.056 7.739 1.00 62.36 ? 151 GLU B CA 1 ATOM 5153 C C . GLU B 1 151 ? 5.905 38.331 7.930 1.00 60.63 ? 151 GLU B C 1 ATOM 5154 O O . GLU B 1 151 ? 6.031 37.174 7.530 1.00 60.34 ? 151 GLU B O 1 ATOM 5155 C CB . GLU B 1 151 ? 4.617 39.943 6.483 1.00 62.71 ? 151 GLU B CB 1 ATOM 5156 C CG . GLU B 1 151 ? 4.841 39.177 5.170 1.00 63.73 ? 151 GLU B CG 1 ATOM 5157 C CD . GLU B 1 151 ? 3.960 37.927 5.036 1.00 65.81 ? 151 GLU B CD 1 ATOM 5158 O OE1 . GLU B 1 151 ? 2.807 37.936 5.528 1.00 66.68 ? 151 GLU B OE1 1 ATOM 5159 O OE2 . GLU B 1 151 ? 4.423 36.931 4.431 1.00 66.51 ? 151 GLU B OE2 1 ATOM 5160 N N . PHE B 1 152 ? 6.877 39.019 8.533 1.00 58.55 ? 152 PHE B N 1 ATOM 5161 C CA . PHE B 1 152 ? 8.189 38.438 8.833 1.00 56.61 ? 152 PHE B CA 1 ATOM 5162 C C . PHE B 1 152 ? 8.056 37.243 9.778 1.00 55.34 ? 152 PHE B C 1 ATOM 5163 O O . PHE B 1 152 ? 8.732 36.226 9.603 1.00 55.02 ? 152 PHE B O 1 ATOM 5164 C CB . PHE B 1 152 ? 9.133 39.494 9.433 1.00 56.51 ? 152 PHE B CB 1 ATOM 5165 C CG . PHE B 1 152 ? 10.448 38.937 9.922 1.00 55.99 ? 152 PHE B CG 1 ATOM 5166 C CD1 . PHE B 1 152 ? 11.426 38.513 9.018 1.00 55.82 ? 152 PHE B CD1 1 ATOM 5167 C CD2 . PHE B 1 152 ? 10.709 38.838 11.287 1.00 55.60 ? 152 PHE B CD2 1 ATOM 5168 C CE1 . PHE B 1 152 ? 12.645 37.993 9.464 1.00 55.35 ? 152 PHE B CE1 1 ATOM 5169 C CE2 . PHE B 1 152 ? 11.922 38.325 11.749 1.00 55.40 ? 152 PHE B CE2 1 ATOM 5170 C CZ . PHE B 1 152 ? 12.892 37.897 10.835 1.00 55.68 ? 152 PHE B CZ 1 ATOM 5171 N N . ASP B 1 153 ? 7.178 37.390 10.768 1.00 53.73 ? 153 ASP B N 1 ATOM 5172 C CA . ASP B 1 153 ? 6.887 36.350 11.747 1.00 52.43 ? 153 ASP B CA 1 ATOM 5173 C C . ASP B 1 153 ? 6.360 35.086 11.062 1.00 52.04 ? 153 ASP B C 1 ATOM 5174 O O . ASP B 1 153 ? 6.910 33.995 11.249 1.00 51.83 ? 153 ASP B O 1 ATOM 5175 C CB . ASP B 1 153 ? 5.886 36.863 12.794 1.00 51.84 ? 153 ASP B CB 1 ATOM 5176 C CG . ASP B 1 153 ? 6.555 37.663 13.926 1.00 51.12 ? 153 ASP B CG 1 ATOM 5177 O OD1 . ASP B 1 153 ? 7.774 37.949 13.860 1.00 48.42 ? 153 ASP B OD1 1 ATOM 5178 O OD2 . ASP B 1 153 ? 5.844 38.000 14.898 1.00 49.48 ? 153 ASP B OD2 1 ATOM 5179 N N . ASP B 1 154 ? 5.308 35.247 10.259 1.00 51.18 ? 154 ASP B N 1 ATOM 5180 C CA . ASP B 1 154 ? 4.727 34.150 9.494 1.00 50.25 ? 154 ASP B CA 1 ATOM 5181 C C . ASP B 1 154 ? 5.732 33.481 8.576 1.00 49.10 ? 154 ASP B C 1 ATOM 5182 O O . ASP B 1 154 ? 5.656 32.277 8.347 1.00 48.87 ? 154 ASP B O 1 ATOM 5183 C CB . ASP B 1 154 ? 3.533 34.638 8.683 1.00 50.84 ? 154 ASP B CB 1 ATOM 5184 C CG . ASP B 1 154 ? 2.357 35.005 9.556 1.00 52.39 ? 154 ASP B CG 1 ATOM 5185 O OD1 . ASP B 1 154 ? 2.590 35.414 10.717 1.00 53.35 ? 154 ASP B OD1 1 ATOM 5186 O OD2 . ASP B 1 154 ? 1.201 34.882 9.084 1.00 54.84 ? 154 ASP B OD2 1 ATOM 5187 N N . SER B 1 155 ? 6.671 34.261 8.056 1.00 47.56 ? 155 SER B N 1 ATOM 5188 C CA . SER B 1 155 ? 7.744 33.720 7.241 1.00 46.36 ? 155 SER B CA 1 ATOM 5189 C C . SER B 1 155 ? 8.553 32.734 8.061 1.00 45.04 ? 155 SER B C 1 ATOM 5190 O O . SER B 1 155 ? 8.976 31.693 7.551 1.00 44.54 ? 155 SER B O 1 ATOM 5191 C CB . SER B 1 155 ? 8.672 34.828 6.747 1.00 46.61 ? 155 SER B CB 1 ATOM 5192 O OG . SER B 1 155 ? 7.943 36.012 6.470 1.00 48.93 ? 155 SER B OG 1 ATOM 5193 N N . LEU B 1 156 ? 8.785 33.078 9.328 1.00 43.47 ? 156 LEU B N 1 ATOM 5194 C CA . LEU B 1 156 ? 9.565 32.215 10.212 1.00 42.35 ? 156 LEU B CA 1 ATOM 5195 C C . LEU B 1 156 ? 8.816 30.914 10.480 1.00 41.21 ? 156 LEU B C 1 ATOM 5196 O O . LEU B 1 156 ? 9.408 29.840 10.414 1.00 40.89 ? 156 LEU B O 1 ATOM 5197 C CB . LEU B 1 156 ? 9.935 32.928 11.522 1.00 42.23 ? 156 LEU B CB 1 ATOM 5198 C CG . LEU B 1 156 ? 10.790 34.194 11.428 1.00 41.89 ? 156 LEU B CG 1 ATOM 5199 C CD1 . LEU B 1 156 ? 10.683 34.994 12.722 1.00 43.05 ? 156 LEU B CD1 1 ATOM 5200 C CD2 . LEU B 1 156 ? 12.250 33.915 11.085 1.00 41.98 ? 156 LEU B CD2 1 ATOM 5201 N N . LEU B 1 157 ? 7.519 31.031 10.763 1.00 40.47 ? 157 LEU B N 1 ATOM 5202 C CA . LEU B 1 157 ? 6.656 29.896 11.070 1.00 40.17 ? 157 LEU B CA 1 ATOM 5203 C C . LEU B 1 157 ? 6.591 28.941 9.875 1.00 39.75 ? 157 LEU B C 1 ATOM 5204 O O . LEU B 1 157 ? 6.710 27.728 10.043 1.00 39.27 ? 157 LEU B O 1 ATOM 5205 C CB . LEU B 1 157 ? 5.254 30.380 11.471 1.00 40.45 ? 157 LEU B CB 1 ATOM 5206 C CG . LEU B 1 157 ? 4.187 29.429 12.031 1.00 41.35 ? 157 LEU B CG 1 ATOM 5207 C CD1 . LEU B 1 157 ? 3.016 30.237 12.567 1.00 41.65 ? 157 LEU B CD1 1 ATOM 5208 C CD2 . LEU B 1 157 ? 3.685 28.398 11.009 1.00 43.81 ? 157 LEU B CD2 1 ATOM 5209 N N . ARG B 1 158 ? 6.425 29.500 8.674 1.00 39.03 ? 158 ARG B N 1 ATOM 5210 C CA . ARG B 1 158 ? 6.437 28.711 7.428 1.00 38.50 ? 158 ARG B CA 1 ATOM 5211 C C . ARG B 1 158 ? 7.779 28.023 7.194 1.00 37.03 ? 158 ARG B C 1 ATOM 5212 O O . ARG B 1 158 ? 7.835 26.967 6.578 1.00 37.15 ? 158 ARG B O 1 ATOM 5213 C CB . ARG B 1 158 ? 6.040 29.562 6.213 1.00 38.65 ? 158 ARG B CB 1 ATOM 5214 C CG . ARG B 1 158 ? 4.580 30.037 6.252 1.00 41.40 ? 158 ARG B CG 1 ATOM 5215 C CD . ARG B 1 158 ? 4.121 30.620 4.906 1.00 45.82 ? 158 ARG B CD 1 ATOM 5216 N NE . ARG B 1 158 ? 5.159 31.445 4.278 1.00 48.16 ? 158 ARG B NE 1 ATOM 5217 C CZ . ARG B 1 158 ? 5.255 32.770 4.388 1.00 49.63 ? 158 ARG B CZ 1 ATOM 5218 N NH1 . ARG B 1 158 ? 4.369 33.461 5.102 1.00 50.09 ? 158 ARG B NH1 1 ATOM 5219 N NH2 . ARG B 1 158 ? 6.243 33.408 3.768 1.00 50.04 ? 158 ARG B NH2 1 ATOM 5220 N N . ASN B 1 159 ? 8.858 28.601 7.709 1.00 35.26 ? 159 ASN B N 1 ATOM 5221 C CA . ASN B 1 159 ? 10.151 27.955 7.584 1.00 33.78 ? 159 ASN B CA 1 ATOM 5222 C C . ASN B 1 159 ? 10.434 26.889 8.652 1.00 32.15 ? 159 ASN B C 1 ATOM 5223 O O . ASN B 1 159 ? 11.415 26.159 8.551 1.00 31.91 ? 159 ASN B O 1 ATOM 5224 C CB . ASN B 1 159 ? 11.295 28.976 7.514 1.00 34.51 ? 159 ASN B CB 1 ATOM 5225 C CG . ASN B 1 159 ? 12.407 28.518 6.597 1.00 37.24 ? 159 ASN B CG 1 ATOM 5226 O OD1 . ASN B 1 159 ? 13.582 28.480 6.986 1.00 39.55 ? 159 ASN B OD1 1 ATOM 5227 N ND2 . ASN B 1 159 ? 12.035 28.143 5.363 1.00 40.41 ? 159 ASN B ND2 1 ATOM 5228 N N . PHE B 1 160 ? 9.573 26.782 9.657 1.00 30.22 ? 160 PHE B N 1 ATOM 5229 C CA . PHE B 1 160 ? 9.810 25.824 10.748 1.00 28.91 ? 160 PHE B CA 1 ATOM 5230 C C . PHE B 1 160 ? 9.006 24.521 10.598 1.00 27.97 ? 160 PHE B C 1 ATOM 5231 O O . PHE B 1 160 ? 9.069 23.647 11.479 1.00 27.53 ? 160 PHE B O 1 ATOM 5232 C CB . PHE B 1 160 ? 9.492 26.440 12.126 1.00 28.27 ? 160 PHE B CB 1 ATOM 5233 C CG . PHE B 1 160 ? 10.467 27.519 12.585 1.00 28.29 ? 160 PHE B CG 1 ATOM 5234 C CD1 . PHE B 1 160 ? 11.622 27.830 11.856 1.00 25.67 ? 160 PHE B CD1 1 ATOM 5235 C CD2 . PHE B 1 160 ? 10.227 28.198 13.786 1.00 27.19 ? 160 PHE B CD2 1 ATOM 5236 C CE1 . PHE B 1 160 ? 12.503 28.833 12.295 1.00 27.96 ? 160 PHE B CE1 1 ATOM 5237 C CE2 . PHE B 1 160 ? 11.113 29.195 14.234 1.00 28.20 ? 160 PHE B CE2 1 ATOM 5238 C CZ . PHE B 1 160 ? 12.250 29.507 13.482 1.00 27.32 ? 160 PHE B CZ 1 ATOM 5239 N N . THR B 1 161 ? 8.226 24.411 9.523 1.00 27.13 ? 161 THR B N 1 ATOM 5240 C CA . THR B 1 161 ? 7.434 23.191 9.276 1.00 26.25 ? 161 THR B CA 1 ATOM 5241 C C . THR B 1 161 ? 7.472 22.836 7.798 1.00 26.26 ? 161 THR B C 1 ATOM 5242 O O . THR B 1 161 ? 7.926 23.629 6.968 1.00 25.71 ? 161 THR B O 1 ATOM 5243 C CB . THR B 1 161 ? 5.934 23.282 9.732 1.00 26.02 ? 161 THR B CB 1 ATOM 5244 O OG1 . THR B 1 161 ? 5.152 23.941 8.731 1.00 26.42 ? 161 THR B OG1 1 ATOM 5245 C CG2 . THR B 1 161 ? 5.749 23.992 11.076 1.00 26.26 ? 161 THR B CG2 1 ATOM 5246 N N . LEU B 1 162 ? 6.988 21.638 7.479 1.00 25.53 ? 162 LEU B N 1 ATOM 5247 C CA . LEU B 1 162 ? 6.888 21.200 6.094 1.00 25.15 ? 162 LEU B CA 1 ATOM 5248 C C . LEU B 1 162 ? 5.557 21.608 5.463 1.00 24.49 ? 162 LEU B C 1 ATOM 5249 O O . LEU B 1 162 ? 5.389 21.481 4.256 1.00 23.79 ? 162 LEU B O 1 ATOM 5250 C CB . LEU B 1 162 ? 7.060 19.677 6.015 1.00 24.56 ? 162 LEU B CB 1 ATOM 5251 C CG . LEU B 1 162 ? 8.442 19.141 6.357 1.00 25.04 ? 162 LEU B CG 1 ATOM 5252 C CD1 . LEU B 1 162 ? 8.409 17.603 6.550 1.00 25.86 ? 162 LEU B CD1 1 ATOM 5253 C CD2 . LEU B 1 162 ? 9.459 19.561 5.279 1.00 26.42 ? 162 LEU B CD2 1 ATOM 5254 N N . VAL B 1 163 ? 4.625 22.077 6.289 1.00 24.13 ? 163 VAL B N 1 ATOM 5255 C CA . VAL B 1 163 ? 3.254 22.339 5.874 1.00 24.83 ? 163 VAL B CA 1 ATOM 5256 C C . VAL B 1 163 ? 3.238 23.290 4.677 1.00 26.21 ? 163 VAL B C 1 ATOM 5257 O O . VAL B 1 163 ? 3.908 24.326 4.686 1.00 26.19 ? 163 VAL B O 1 ATOM 5258 C CB . VAL B 1 163 ? 2.393 22.951 7.038 1.00 24.60 ? 163 VAL B CB 1 ATOM 5259 C CG1 . VAL B 1 163 ? 1.035 23.398 6.523 1.00 23.85 ? 163 VAL B CG1 1 ATOM 5260 C CG2 . VAL B 1 163 ? 2.207 21.941 8.199 1.00 23.09 ? 163 VAL B CG2 1 ATOM 5261 N N . THR B 1 164 ? 2.483 22.932 3.648 1.00 27.53 ? 164 THR B N 1 ATOM 5262 C CA . THR B 1 164 ? 2.353 23.774 2.470 1.00 28.91 ? 164 THR B CA 1 ATOM 5263 C C . THR B 1 164 ? 1.141 23.353 1.663 1.00 29.86 ? 164 THR B C 1 ATOM 5264 O O . THR B 1 164 ? 0.664 22.223 1.790 1.00 29.27 ? 164 THR B O 1 ATOM 5265 C CB . THR B 1 164 ? 3.627 23.724 1.574 1.00 29.22 ? 164 THR B CB 1 ATOM 5266 O OG1 . THR B 1 164 ? 3.478 24.655 0.496 1.00 32.58 ? 164 THR B OG1 1 ATOM 5267 C CG2 . THR B 1 164 ? 3.885 22.305 0.985 1.00 29.04 ? 164 THR B CG2 1 ATOM 5268 N N . GLN B 1 165 ? 0.632 24.282 0.850 1.00 30.83 ? 165 GLN B N 1 ATOM 5269 C CA . GLN B 1 165 ? -0.292 23.960 -0.226 1.00 31.71 ? 165 GLN B CA 1 ATOM 5270 C C . GLN B 1 165 ? 0.545 23.323 -1.312 1.00 31.02 ? 165 GLN B C 1 ATOM 5271 O O . GLN B 1 165 ? 1.723 23.609 -1.431 1.00 31.72 ? 165 GLN B O 1 ATOM 5272 C CB . GLN B 1 165 ? -0.904 25.249 -0.775 1.00 32.67 ? 165 GLN B CB 1 ATOM 5273 C CG . GLN B 1 165 ? -2.046 25.814 0.028 1.00 36.08 ? 165 GLN B CG 1 ATOM 5274 C CD . GLN B 1 165 ? -2.714 26.967 -0.698 1.00 42.30 ? 165 GLN B CD 1 ATOM 5275 O OE1 . GLN B 1 165 ? -2.300 28.124 -0.560 1.00 44.47 ? 165 GLN B OE1 1 ATOM 5276 N NE2 . GLN B 1 165 ? -3.757 26.657 -1.486 1.00 43.30 ? 165 GLN B NE2 1 ATOM 5277 N N . HIS B 1 166 ? -0.054 22.453 -2.102 1.00 31.04 ? 166 HIS B N 1 ATOM 5278 C CA . HIS B 1 166 ? 0.650 21.781 -3.211 1.00 30.69 ? 166 HIS B CA 1 ATOM 5279 C C . HIS B 1 166 ? 1.967 21.068 -2.847 1.00 29.62 ? 166 HIS B C 1 ATOM 5280 O O . HIS B 1 166 ? 2.984 21.239 -3.529 1.00 29.51 ? 166 HIS B O 1 ATOM 5281 C CB . HIS B 1 166 ? 0.810 22.733 -4.409 1.00 31.72 ? 166 HIS B CB 1 ATOM 5282 C CG . HIS B 1 166 ? -0.453 23.462 -4.737 1.00 33.83 ? 166 HIS B CG 1 ATOM 5283 N ND1 . HIS B 1 166 ? -0.608 24.815 -4.520 1.00 38.11 ? 166 HIS B ND1 1 ATOM 5284 C CD2 . HIS B 1 166 ? -1.644 23.014 -5.190 1.00 36.99 ? 166 HIS B CD2 1 ATOM 5285 C CE1 . HIS B 1 166 ? -1.829 25.177 -4.868 1.00 38.81 ? 166 HIS B CE1 1 ATOM 5286 N NE2 . HIS B 1 166 ? -2.480 24.102 -5.274 1.00 38.75 ? 166 HIS B NE2 1 ATOM 5287 N N . PRO B 1 167 ? 1.928 20.211 -1.807 1.00 28.06 ? 167 PRO B N 1 ATOM 5288 C CA . PRO B 1 167 ? 3.128 19.450 -1.465 1.00 27.47 ? 167 PRO B CA 1 ATOM 5289 C C . PRO B 1 167 ? 3.593 18.485 -2.577 1.00 27.40 ? 167 PRO B C 1 ATOM 5290 O O . PRO B 1 167 ? 4.760 18.127 -2.617 1.00 26.62 ? 167 PRO B O 1 ATOM 5291 C CB . PRO B 1 167 ? 2.722 18.710 -0.179 1.00 26.72 ? 167 PRO B CB 1 ATOM 5292 C CG . PRO B 1 167 ? 1.227 18.578 -0.267 1.00 27.07 ? 167 PRO B CG 1 ATOM 5293 C CD . PRO B 1 167 ? 0.768 19.840 -0.964 1.00 27.95 ? 167 PRO B CD 1 ATOM 5294 N N . GLU B 1 168 ? 2.702 18.098 -3.485 1.00 28.26 ? 168 GLU B N 1 ATOM 5295 C CA . GLU B 1 168 ? 3.087 17.288 -4.665 1.00 29.73 ? 168 GLU B CA 1 ATOM 5296 C C . GLU B 1 168 ? 3.982 18.087 -5.636 1.00 30.18 ? 168 GLU B C 1 ATOM 5297 O O . GLU B 1 168 ? 4.892 17.535 -6.268 1.00 30.88 ? 168 GLU B O 1 ATOM 5298 C CB . GLU B 1 168 ? 1.839 16.740 -5.378 1.00 30.36 ? 168 GLU B CB 1 ATOM 5299 C CG . GLU B 1 168 ? 0.990 17.788 -6.145 1.00 32.19 ? 168 GLU B CG 1 ATOM 5300 C CD . GLU B 1 168 ? 0.186 18.744 -5.246 1.00 36.49 ? 168 GLU B CD 1 ATOM 5301 O OE1 . GLU B 1 168 ? -0.234 19.817 -5.744 1.00 38.65 ? 168 GLU B OE1 1 ATOM 5302 O OE2 . GLU B 1 168 ? -0.040 18.438 -4.050 1.00 37.63 ? 168 GLU B OE2 1 ATOM 5303 N N . VAL B 1 169 ? 3.732 19.395 -5.715 1.00 30.21 ? 169 VAL B N 1 ATOM 5304 C CA . VAL B 1 169 ? 4.538 20.326 -6.495 1.00 29.60 ? 169 VAL B CA 1 ATOM 5305 C C . VAL B 1 169 ? 5.836 20.687 -5.784 1.00 28.98 ? 169 VAL B C 1 ATOM 5306 O O . VAL B 1 169 ? 6.915 20.663 -6.378 1.00 28.85 ? 169 VAL B O 1 ATOM 5307 C CB . VAL B 1 169 ? 3.745 21.635 -6.795 1.00 29.94 ? 169 VAL B CB 1 ATOM 5308 C CG1 . VAL B 1 169 ? 4.602 22.620 -7.605 1.00 31.10 ? 169 VAL B CG1 1 ATOM 5309 C CG2 . VAL B 1 169 ? 2.446 21.324 -7.531 1.00 30.22 ? 169 VAL B CG2 1 ATOM 5310 N N . ILE B 1 170 ? 5.728 21.036 -4.504 1.00 27.94 ? 170 ILE B N 1 ATOM 5311 C CA . ILE B 1 170 ? 6.874 21.504 -3.735 1.00 27.18 ? 170 ILE B CA 1 ATOM 5312 C C . ILE B 1 170 ? 7.852 20.351 -3.462 1.00 25.67 ? 170 ILE B C 1 ATOM 5313 O O . ILE B 1 170 ? 9.060 20.510 -3.614 1.00 24.66 ? 170 ILE B O 1 ATOM 5314 C CB . ILE B 1 170 ? 6.409 22.199 -2.409 1.00 27.51 ? 170 ILE B CB 1 ATOM 5315 C CG1 . ILE B 1 170 ? 5.460 23.369 -2.713 1.00 30.94 ? 170 ILE B CG1 1 ATOM 5316 C CG2 . ILE B 1 170 ? 7.594 22.657 -1.546 1.00 28.79 ? 170 ILE B CG2 1 ATOM 5317 C CD1 . ILE B 1 170 ? 5.996 24.396 -3.740 1.00 32.51 ? 170 ILE B CD1 1 ATOM 5318 N N . TYR B 1 171 ? 7.337 19.191 -3.056 1.00 23.88 ? 171 TYR B N 1 ATOM 5319 C CA . TYR B 1 171 ? 8.234 18.088 -2.727 1.00 22.80 ? 171 TYR B CA 1 ATOM 5320 C C . TYR B 1 171 ? 8.040 17.023 -3.768 1.00 22.77 ? 171 TYR B C 1 ATOM 5321 O O . TYR B 1 171 ? 7.115 16.226 -3.677 1.00 22.72 ? 171 TYR B O 1 ATOM 5322 C CB . TYR B 1 171 ? 7.965 17.524 -1.331 1.00 22.49 ? 171 TYR B CB 1 ATOM 5323 C CG . TYR B 1 171 ? 7.863 18.573 -0.246 1.00 22.12 ? 171 TYR B CG 1 ATOM 5324 C CD1 . TYR B 1 171 ? 8.940 19.406 0.052 1.00 22.10 ? 171 TYR B CD1 1 ATOM 5325 C CD2 . TYR B 1 171 ? 6.690 18.713 0.495 1.00 22.30 ? 171 TYR B CD2 1 ATOM 5326 C CE1 . TYR B 1 171 ? 8.848 20.376 1.068 1.00 23.26 ? 171 TYR B CE1 1 ATOM 5327 C CE2 . TYR B 1 171 ? 6.589 19.658 1.510 1.00 20.92 ? 171 TYR B CE2 1 ATOM 5328 C CZ . TYR B 1 171 ? 7.665 20.487 1.785 1.00 24.47 ? 171 TYR B CZ 1 ATOM 5329 O OH . TYR B 1 171 ? 7.553 21.437 2.784 1.00 24.78 ? 171 TYR B OH 1 ATOM 5330 N N . THR B 1 172 ? 8.914 17.017 -4.764 1.00 22.64 ? 172 THR B N 1 ATOM 5331 C CA . THR B 1 172 ? 8.667 16.201 -5.940 1.00 23.21 ? 172 THR B CA 1 ATOM 5332 C C . THR B 1 172 ? 9.165 14.766 -5.757 1.00 22.56 ? 172 THR B C 1 ATOM 5333 O O . THR B 1 172 ? 8.685 13.863 -6.447 1.00 22.53 ? 172 THR B O 1 ATOM 5334 C CB . THR B 1 172 ? 9.259 16.838 -7.194 1.00 23.53 ? 172 THR B CB 1 ATOM 5335 O OG1 . THR B 1 172 ? 10.679 16.908 -7.051 1.00 24.07 ? 172 THR B OG1 1 ATOM 5336 C CG2 . THR B 1 172 ? 8.692 18.282 -7.381 1.00 25.73 ? 172 THR B CG2 1 ATOM 5337 N N . ASN B 1 173 ? 10.132 14.570 -4.850 1.00 21.38 ? 173 ASN B N 1 ATOM 5338 C CA . ASN B 1 173 ? 10.567 13.217 -4.461 1.00 20.58 ? 173 ASN B CA 1 ATOM 5339 C C . ASN B 1 173 ? 10.952 13.120 -2.972 1.00 20.28 ? 173 ASN B C 1 ATOM 5340 O O . ASN B 1 173 ? 10.904 14.119 -2.254 1.00 19.07 ? 173 ASN B O 1 ATOM 5341 C CB . ASN B 1 173 ? 11.690 12.707 -5.364 1.00 20.31 ? 173 ASN B CB 1 ATOM 5342 C CG . ASN B 1 173 ? 12.962 13.553 -5.268 1.00 22.02 ? 173 ASN B CG 1 ATOM 5343 O OD1 . ASN B 1 173 ? 13.614 13.610 -4.226 1.00 21.22 ? 173 ASN B OD1 1 ATOM 5344 N ND2 . ASN B 1 173 ? 13.332 14.188 -6.382 1.00 20.32 ? 173 ASN B ND2 1 ATOM 5345 N N . GLN B 1 174 ? 11.330 11.918 -2.528 1.00 19.19 ? 174 GLN B N 1 ATOM 5346 C CA . GLN B 1 174 ? 11.691 11.670 -1.138 1.00 19.53 ? 174 GLN B CA 1 ATOM 5347 C C . GLN B 1 174 ? 12.991 12.321 -0.700 1.00 20.53 ? 174 GLN B C 1 ATOM 5348 O O . GLN B 1 174 ? 13.122 12.713 0.462 1.00 20.60 ? 174 GLN B O 1 ATOM 5349 C CB . GLN B 1 174 ? 11.719 10.157 -0.861 1.00 19.33 ? 174 GLN B CB 1 ATOM 5350 C CG . GLN B 1 174 ? 10.269 9.589 -0.898 1.00 20.22 ? 174 GLN B CG 1 ATOM 5351 C CD . GLN B 1 174 ? 10.202 8.069 -0.908 1.00 22.88 ? 174 GLN B CD 1 ATOM 5352 O OE1 . GLN B 1 174 ? 9.217 7.499 -1.367 1.00 26.54 ? 174 GLN B OE1 1 ATOM 5353 N NE2 . GLN B 1 174 ? 11.228 7.414 -0.385 1.00 22.34 ? 174 GLN B NE2 1 ATOM 5354 N N . ASN B 1 175 ? 13.947 12.449 -1.618 1.00 21.34 ? 175 ASN B N 1 ATOM 5355 C CA . ASN B 1 175 ? 15.194 13.147 -1.301 1.00 21.91 ? 175 ASN B CA 1 ATOM 5356 C C . ASN B 1 175 ? 14.944 14.637 -1.074 1.00 21.57 ? 175 ASN B C 1 ATOM 5357 O O . ASN B 1 175 ? 15.497 15.231 -0.150 1.00 21.95 ? 175 ASN B O 1 ATOM 5358 C CB . ASN B 1 175 ? 16.265 12.896 -2.369 1.00 22.16 ? 175 ASN B CB 1 ATOM 5359 C CG . ASN B 1 175 ? 16.876 11.515 -2.263 1.00 24.01 ? 175 ASN B CG 1 ATOM 5360 O OD1 . ASN B 1 175 ? 16.617 10.772 -1.306 1.00 25.47 ? 175 ASN B OD1 1 ATOM 5361 N ND2 . ASN B 1 175 ? 17.703 11.160 -3.236 1.00 24.26 ? 175 ASN B ND2 1 ATOM 5362 N N . VAL B 1 176 ? 14.058 15.227 -1.866 1.00 21.65 ? 176 VAL B N 1 ATOM 5363 C CA . VAL B 1 176 ? 13.710 16.631 -1.680 1.00 21.39 ? 176 VAL B CA 1 ATOM 5364 C C . VAL B 1 176 ? 13.002 16.897 -0.327 1.00 21.43 ? 176 VAL B C 1 ATOM 5365 O O . VAL B 1 176 ? 13.379 17.838 0.399 1.00 20.36 ? 176 VAL B O 1 ATOM 5366 C CB . VAL B 1 176 ? 12.878 17.207 -2.862 1.00 22.24 ? 176 VAL B CB 1 ATOM 5367 C CG1 . VAL B 1 176 ? 12.496 18.681 -2.606 1.00 20.83 ? 176 VAL B CG1 1 ATOM 5368 C CG2 . VAL B 1 176 ? 13.657 17.062 -4.209 1.00 21.99 ? 176 VAL B CG2 1 ATOM 5369 N N . VAL B 1 177 ? 11.990 16.089 0.008 1.00 19.64 ? 177 VAL B N 1 ATOM 5370 C CA . VAL B 1 177 ? 11.321 16.270 1.299 1.00 18.90 ? 177 VAL B CA 1 ATOM 5371 C C . VAL B 1 177 ? 12.290 16.054 2.490 1.00 18.60 ? 177 VAL B C 1 ATOM 5372 O O . VAL B 1 177 ? 12.272 16.820 3.463 1.00 18.06 ? 177 VAL B O 1 ATOM 5373 C CB . VAL B 1 177 ? 9.946 15.501 1.394 1.00 18.73 ? 177 VAL B CB 1 ATOM 5374 C CG1 . VAL B 1 177 ? 10.109 13.981 1.677 1.00 17.69 ? 177 VAL B CG1 1 ATOM 5375 C CG2 . VAL B 1 177 ? 9.038 16.161 2.430 1.00 19.92 ? 177 VAL B CG2 1 ATOM 5376 N N . TRP B 1 178 ? 13.172 15.061 2.384 1.00 18.90 ? 178 TRP B N 1 ATOM 5377 C CA . TRP B 1 178 ? 14.186 14.824 3.419 1.00 20.31 ? 178 TRP B CA 1 ATOM 5378 C C . TRP B 1 178 ? 15.211 15.951 3.556 1.00 21.31 ? 178 TRP B C 1 ATOM 5379 O O . TRP B 1 178 ? 15.664 16.253 4.666 1.00 20.55 ? 178 TRP B O 1 ATOM 5380 C CB . TRP B 1 178 ? 14.885 13.474 3.236 1.00 19.87 ? 178 TRP B CB 1 ATOM 5381 C CG . TRP B 1 178 ? 14.226 12.430 4.052 1.00 20.88 ? 178 TRP B CG 1 ATOM 5382 C CD1 . TRP B 1 178 ? 13.269 11.553 3.639 1.00 21.56 ? 178 TRP B CD1 1 ATOM 5383 C CD2 . TRP B 1 178 ? 14.424 12.182 5.456 1.00 21.05 ? 178 TRP B CD2 1 ATOM 5384 N NE1 . TRP B 1 178 ? 12.871 10.760 4.690 1.00 22.70 ? 178 TRP B NE1 1 ATOM 5385 C CE2 . TRP B 1 178 ? 13.567 11.116 5.814 1.00 21.78 ? 178 TRP B CE2 1 ATOM 5386 C CE3 . TRP B 1 178 ? 15.266 12.741 6.438 1.00 21.52 ? 178 TRP B CE3 1 ATOM 5387 C CZ2 . TRP B 1 178 ? 13.521 10.585 7.119 1.00 23.03 ? 178 TRP B CZ2 1 ATOM 5388 C CZ3 . TRP B 1 178 ? 15.209 12.225 7.746 1.00 23.09 ? 178 TRP B CZ3 1 ATOM 5389 C CH2 . TRP B 1 178 ? 14.342 11.154 8.071 1.00 19.80 ? 178 TRP B CH2 1 ATOM 5390 N N . SER B 1 179 ? 15.554 16.572 2.427 1.00 21.54 ? 179 SER B N 1 ATOM 5391 C CA . SER B 1 179 ? 16.459 17.697 2.430 1.00 23.73 ? 179 SER B CA 1 ATOM 5392 C C . SER B 1 179 ? 15.834 18.863 3.199 1.00 22.99 ? 179 SER B C 1 ATOM 5393 O O . SER B 1 179 ? 16.474 19.411 4.090 1.00 23.17 ? 179 SER B O 1 ATOM 5394 C CB . SER B 1 179 ? 16.820 18.135 1.007 1.00 23.46 ? 179 SER B CB 1 ATOM 5395 O OG . SER B 1 179 ? 17.912 19.017 1.094 1.00 27.64 ? 179 SER B OG 1 ATOM 5396 N N . LYS B 1 180 ? 14.581 19.190 2.898 1.00 22.98 ? 180 LYS B N 1 ATOM 5397 C CA . LYS B 1 180 ? 13.872 20.227 3.644 1.00 24.13 ? 180 LYS B CA 1 ATOM 5398 C C . LYS B 1 180 ? 13.659 19.880 5.119 1.00 24.13 ? 180 LYS B C 1 ATOM 5399 O O . LYS B 1 180 ? 13.843 20.743 5.986 1.00 23.79 ? 180 LYS B O 1 ATOM 5400 C CB . LYS B 1 180 ? 12.538 20.587 2.996 1.00 24.45 ? 180 LYS B CB 1 ATOM 5401 C CG . LYS B 1 180 ? 12.617 20.868 1.486 1.00 27.69 ? 180 LYS B CG 1 ATOM 5402 C CD . LYS B 1 180 ? 13.193 22.257 1.192 1.00 32.67 ? 180 LYS B CD 1 ATOM 5403 C CE . LYS B 1 180 ? 13.126 22.577 -0.296 1.00 34.72 ? 180 LYS B CE 1 ATOM 5404 N NZ . LYS B 1 180 ? 13.653 23.954 -0.530 1.00 37.20 ? 180 LYS B NZ 1 ATOM 5405 N N . PHE B 1 181 ? 13.250 18.632 5.382 1.00 24.18 ? 181 PHE B N 1 ATOM 5406 C CA . PHE B 1 181 ? 13.050 18.103 6.736 1.00 25.19 ? 181 PHE B CA 1 ATOM 5407 C C . PHE B 1 181 ? 14.260 18.373 7.622 1.00 25.93 ? 181 PHE B C 1 ATOM 5408 O O . PHE B 1 181 ? 14.152 19.061 8.634 1.00 25.99 ? 181 PHE B O 1 ATOM 5409 C CB . PHE B 1 181 ? 12.773 16.591 6.660 1.00 24.79 ? 181 PHE B CB 1 ATOM 5410 C CG . PHE B 1 181 ? 12.173 15.981 7.912 1.00 24.56 ? 181 PHE B CG 1 ATOM 5411 C CD1 . PHE B 1 181 ? 11.235 16.664 8.688 1.00 24.31 ? 181 PHE B CD1 1 ATOM 5412 C CD2 . PHE B 1 181 ? 12.501 14.679 8.263 1.00 23.90 ? 181 PHE B CD2 1 ATOM 5413 C CE1 . PHE B 1 181 ? 10.675 16.074 9.812 1.00 25.36 ? 181 PHE B CE1 1 ATOM 5414 C CE2 . PHE B 1 181 ? 11.944 14.072 9.395 1.00 24.91 ? 181 PHE B CE2 1 ATOM 5415 C CZ . PHE B 1 181 ? 11.027 14.770 10.172 1.00 24.40 ? 181 PHE B CZ 1 ATOM 5416 N N . GLU B 1 182 ? 15.407 17.845 7.226 1.00 26.45 ? 182 GLU B N 1 ATOM 5417 C CA . GLU B 1 182 ? 16.653 18.021 7.980 1.00 28.27 ? 182 GLU B CA 1 ATOM 5418 C C . GLU B 1 182 ? 17.131 19.461 8.114 1.00 28.01 ? 182 GLU B C 1 ATOM 5419 O O . GLU B 1 182 ? 17.667 19.837 9.164 1.00 28.30 ? 182 GLU B O 1 ATOM 5420 C CB . GLU B 1 182 ? 17.746 17.170 7.353 1.00 29.21 ? 182 GLU B CB 1 ATOM 5421 C CG . GLU B 1 182 ? 17.452 15.708 7.558 1.00 32.94 ? 182 GLU B CG 1 ATOM 5422 C CD . GLU B 1 182 ? 18.370 14.803 6.779 1.00 39.47 ? 182 GLU B CD 1 ATOM 5423 O OE1 . GLU B 1 182 ? 18.737 13.753 7.343 1.00 41.73 ? 182 GLU B OE1 1 ATOM 5424 O OE2 . GLU B 1 182 ? 18.707 15.126 5.609 1.00 42.73 ? 182 GLU B OE2 1 ATOM 5425 N N . THR B 1 183 ? 16.926 20.262 7.067 1.00 27.23 ? 183 THR B N 1 ATOM 5426 C CA . THR B 1 183 ? 17.207 21.692 7.132 1.00 27.32 ? 183 THR B CA 1 ATOM 5427 C C . THR B 1 183 ? 16.390 22.410 8.234 1.00 26.87 ? 183 THR B C 1 ATOM 5428 O O . THR B 1 183 ? 16.890 23.352 8.870 1.00 26.68 ? 183 THR B O 1 ATOM 5429 C CB . THR B 1 183 ? 17.009 22.372 5.757 1.00 27.53 ? 183 THR B CB 1 ATOM 5430 O OG1 . THR B 1 183 ? 17.911 21.780 4.821 1.00 27.92 ? 183 THR B OG1 1 ATOM 5431 C CG2 . THR B 1 183 ? 17.283 23.879 5.824 1.00 28.27 ? 183 THR B CG2 1 ATOM 5432 N N . ILE B 1 184 ? 15.146 21.986 8.444 1.00 25.98 ? 184 ILE B N 1 ATOM 5433 C CA . ILE B 1 184 ? 14.359 22.493 9.564 1.00 25.35 ? 184 ILE B CA 1 ATOM 5434 C C . ILE B 1 184 ? 15.051 22.203 10.907 1.00 25.30 ? 184 ILE B C 1 ATOM 5435 O O . ILE B 1 184 ? 15.138 23.091 11.755 1.00 24.67 ? 184 ILE B O 1 ATOM 5436 C CB . ILE B 1 184 ? 12.916 21.940 9.578 1.00 25.30 ? 184 ILE B CB 1 ATOM 5437 C CG1 . ILE B 1 184 ? 12.126 22.454 8.372 1.00 25.20 ? 184 ILE B CG1 1 ATOM 5438 C CG2 . ILE B 1 184 ? 12.196 22.319 10.889 1.00 23.67 ? 184 ILE B CG2 1 ATOM 5439 C CD1 . ILE B 1 184 ? 10.824 21.675 8.163 1.00 25.71 ? 184 ILE B CD1 1 ATOM 5440 N N . PHE B 1 185 ? 15.538 20.971 11.096 1.00 25.15 ? 185 PHE B N 1 ATOM 5441 C CA . PHE B 1 185 ? 16.232 20.615 12.321 1.00 26.24 ? 185 PHE B CA 1 ATOM 5442 C C . PHE B 1 185 ? 17.477 21.505 12.534 1.00 26.18 ? 185 PHE B C 1 ATOM 5443 O O . PHE B 1 185 ? 17.694 22.001 13.639 1.00 24.25 ? 185 PHE B O 1 ATOM 5444 C CB . PHE B 1 185 ? 16.569 19.104 12.382 1.00 25.62 ? 185 PHE B CB 1 ATOM 5445 C CG . PHE B 1 185 ? 15.340 18.212 12.530 1.00 28.76 ? 185 PHE B CG 1 ATOM 5446 C CD1 . PHE B 1 185 ? 14.902 17.801 13.789 1.00 31.24 ? 185 PHE B CD1 1 ATOM 5447 C CD2 . PHE B 1 185 ? 14.620 17.792 11.418 1.00 29.64 ? 185 PHE B CD2 1 ATOM 5448 C CE1 . PHE B 1 185 ? 13.751 16.993 13.937 1.00 32.03 ? 185 PHE B CE1 1 ATOM 5449 C CE2 . PHE B 1 185 ? 13.494 16.979 11.549 1.00 31.45 ? 185 PHE B CE2 1 ATOM 5450 C CZ . PHE B 1 185 ? 13.055 16.582 12.816 1.00 31.25 ? 185 PHE B CZ 1 ATOM 5451 N N . PHE B 1 186 ? 18.244 21.739 11.468 1.00 26.56 ? 186 PHE B N 1 ATOM 5452 C CA . PHE B 1 186 ? 19.415 22.625 11.531 1.00 27.89 ? 186 PHE B CA 1 ATOM 5453 C C . PHE B 1 186 ? 19.040 24.040 11.966 1.00 27.89 ? 186 PHE B C 1 ATOM 5454 O O . PHE B 1 186 ? 19.675 24.608 12.861 1.00 28.16 ? 186 PHE B O 1 ATOM 5455 C CB . PHE B 1 186 ? 20.159 22.683 10.186 1.00 28.18 ? 186 PHE B CB 1 ATOM 5456 C CG . PHE B 1 186 ? 21.250 23.731 10.146 1.00 30.38 ? 186 PHE B CG 1 ATOM 5457 C CD1 . PHE B 1 186 ? 21.000 24.998 9.638 1.00 31.95 ? 186 PHE B CD1 1 ATOM 5458 C CD2 . PHE B 1 186 ? 22.524 23.445 10.629 1.00 32.83 ? 186 PHE B CD2 1 ATOM 5459 C CE1 . PHE B 1 186 ? 22.003 25.975 9.606 1.00 33.50 ? 186 PHE B CE1 1 ATOM 5460 C CE2 . PHE B 1 186 ? 23.545 24.418 10.606 1.00 34.11 ? 186 PHE B CE2 1 ATOM 5461 C CZ . PHE B 1 186 ? 23.280 25.680 10.091 1.00 32.84 ? 186 PHE B CZ 1 ATOM 5462 N N . THR B 1 187 ? 18.010 24.587 11.327 1.00 27.65 ? 187 THR B N 1 ATOM 5463 C CA . THR B 1 187 ? 17.531 25.959 11.556 1.00 27.77 ? 187 THR B CA 1 ATOM 5464 C C . THR B 1 187 ? 16.989 26.208 12.983 1.00 28.22 ? 187 THR B C 1 ATOM 5465 O O . THR B 1 187 ? 17.338 27.211 13.618 1.00 28.26 ? 187 THR B O 1 ATOM 5466 C CB . THR B 1 187 ? 16.481 26.339 10.484 1.00 27.84 ? 187 THR B CB 1 ATOM 5467 O OG1 . THR B 1 187 ? 17.118 26.418 9.196 1.00 27.25 ? 187 THR B OG1 1 ATOM 5468 C CG2 . THR B 1 187 ? 15.799 27.672 10.800 1.00 28.75 ? 187 THR B CG2 1 ATOM 5469 N N . ILE B 1 188 ? 16.161 25.298 13.498 1.00 28.02 ? 188 ILE B N 1 ATOM 5470 C CA . ILE B 1 188 ? 15.566 25.495 14.839 1.00 27.51 ? 188 ILE B CA 1 ATOM 5471 C C . ILE B 1 188 ? 16.500 25.116 15.985 1.00 27.73 ? 188 ILE B C 1 ATOM 5472 O O . ILE B 1 188 ? 16.255 25.487 17.151 1.00 27.60 ? 188 ILE B O 1 ATOM 5473 C CB . ILE B 1 188 ? 14.217 24.758 15.008 1.00 27.61 ? 188 ILE B CB 1 ATOM 5474 C CG1 . ILE B 1 188 ? 14.439 23.238 14.991 1.00 26.75 ? 188 ILE B CG1 1 ATOM 5475 C CG2 . ILE B 1 188 ? 13.189 25.274 13.961 1.00 25.34 ? 188 ILE B CG2 1 ATOM 5476 C CD1 . ILE B 1 188 ? 13.222 22.428 15.276 1.00 27.94 ? 188 ILE B CD1 1 ATOM 5477 N N . SER B 1 189 ? 17.567 24.401 15.644 1.00 27.37 ? 189 SER B N 1 ATOM 5478 C CA . SER B 1 189 ? 18.449 23.780 16.629 1.00 28.75 ? 189 SER B CA 1 ATOM 5479 C C . SER B 1 189 ? 19.073 24.798 17.614 1.00 28.62 ? 189 SER B C 1 ATOM 5480 O O . SER B 1 189 ? 19.130 24.548 18.826 1.00 27.89 ? 189 SER B O 1 ATOM 5481 C CB . SER B 1 189 ? 19.544 22.980 15.916 1.00 29.04 ? 189 SER B CB 1 ATOM 5482 O OG . SER B 1 189 ? 20.450 22.411 16.842 1.00 31.58 ? 189 SER B OG 1 ATOM 5483 N N . GLY B 1 190 ? 19.523 25.931 17.076 1.00 28.27 ? 190 GLY B N 1 ATOM 5484 C CA . GLY B 1 190 ? 20.090 27.014 17.865 1.00 28.66 ? 190 GLY B CA 1 ATOM 5485 C C . GLY B 1 190 ? 19.105 27.700 18.798 1.00 28.67 ? 190 GLY B C 1 ATOM 5486 O O . GLY B 1 190 ? 19.505 28.245 19.831 1.00 29.70 ? 190 GLY B O 1 ATOM 5487 N N . LEU B 1 191 ? 17.823 27.702 18.445 1.00 27.98 ? 191 LEU B N 1 ATOM 5488 C CA . LEU B 1 191 ? 16.811 28.252 19.343 1.00 27.76 ? 191 LEU B CA 1 ATOM 5489 C C . LEU B 1 191 ? 16.634 27.340 20.560 1.00 28.39 ? 191 LEU B C 1 ATOM 5490 O O . LEU B 1 191 ? 16.579 27.822 21.703 1.00 28.66 ? 191 LEU B O 1 ATOM 5491 C CB . LEU B 1 191 ? 15.468 28.468 18.640 1.00 27.27 ? 191 LEU B CB 1 ATOM 5492 C CG . LEU B 1 191 ? 15.304 29.566 17.585 1.00 27.41 ? 191 LEU B CG 1 ATOM 5493 C CD1 . LEU B 1 191 ? 13.913 29.497 16.975 1.00 27.92 ? 191 LEU B CD1 1 ATOM 5494 C CD2 . LEU B 1 191 ? 15.545 30.976 18.182 1.00 25.94 ? 191 LEU B CD2 1 ATOM 5495 N N . ILE B 1 192 ? 16.574 26.030 20.305 1.00 27.90 ? 192 ILE B N 1 ATOM 5496 C CA . ILE B 1 192 ? 16.171 25.034 21.310 1.00 27.37 ? 192 ILE B CA 1 ATOM 5497 C C . ILE B 1 192 ? 17.302 24.625 22.257 1.00 27.14 ? 192 ILE B C 1 ATOM 5498 O O . ILE B 1 192 ? 17.050 24.323 23.432 1.00 27.15 ? 192 ILE B O 1 ATOM 5499 C CB . ILE B 1 192 ? 15.470 23.782 20.640 1.00 27.47 ? 192 ILE B CB 1 ATOM 5500 C CG1 . ILE B 1 192 ? 14.174 24.213 19.931 1.00 27.07 ? 192 ILE B CG1 1 ATOM 5501 C CG2 . ILE B 1 192 ? 15.159 22.689 21.667 1.00 27.46 ? 192 ILE B CG2 1 ATOM 5502 C CD1 . ILE B 1 192 ? 13.566 23.158 18.961 1.00 24.78 ? 192 ILE B CD1 1 ATOM 5503 N N . HIS B 1 193 ? 18.543 24.648 21.770 1.00 25.96 ? 193 HIS B N 1 ATOM 5504 C CA . HIS B 1 193 ? 19.680 24.269 22.590 1.00 26.21 ? 193 HIS B CA 1 ATOM 5505 C C . HIS B 1 193 ? 20.268 25.359 23.502 1.00 25.88 ? 193 HIS B C 1 ATOM 5506 O O . HIS B 1 193 ? 21.250 25.124 24.181 1.00 26.21 ? 193 HIS B O 1 ATOM 5507 C CB . HIS B 1 193 ? 20.746 23.579 21.750 1.00 26.08 ? 193 HIS B CB 1 ATOM 5508 C CG . HIS B 1 193 ? 20.276 22.278 21.193 1.00 28.63 ? 193 HIS B CG 1 ATOM 5509 N ND1 . HIS B 1 193 ? 20.527 21.068 21.807 1.00 31.39 ? 193 HIS B ND1 1 ATOM 5510 C CD2 . HIS B 1 193 ? 19.485 22.004 20.131 1.00 27.52 ? 193 HIS B CD2 1 ATOM 5511 C CE1 . HIS B 1 193 ? 19.949 20.101 21.116 1.00 28.94 ? 193 HIS B CE1 1 ATOM 5512 N NE2 . HIS B 1 193 ? 19.320 20.641 20.090 1.00 30.46 ? 193 HIS B NE2 1 ATOM 5513 N N . TYR B 1 194 ? 19.655 26.533 23.538 1.00 25.37 ? 194 TYR B N 1 ATOM 5514 C CA . TYR B 1 194 ? 20.012 27.521 24.574 1.00 25.89 ? 194 TYR B CA 1 ATOM 5515 C C . TYR B 1 194 ? 19.342 27.068 25.884 1.00 25.08 ? 194 TYR B C 1 ATOM 5516 O O . TYR B 1 194 ? 18.172 26.765 25.882 1.00 25.02 ? 194 TYR B O 1 ATOM 5517 C CB . TYR B 1 194 ? 19.601 28.924 24.116 1.00 25.45 ? 194 TYR B CB 1 ATOM 5518 C CG . TYR B 1 194 ? 19.627 30.027 25.157 1.00 27.43 ? 194 TYR B CG 1 ATOM 5519 C CD1 . TYR B 1 194 ? 20.788 30.321 25.873 1.00 29.21 ? 194 TYR B CD1 1 ATOM 5520 C CD2 . TYR B 1 194 ? 18.488 30.797 25.395 1.00 26.60 ? 194 TYR B CD2 1 ATOM 5521 C CE1 . TYR B 1 194 ? 20.804 31.327 26.817 1.00 30.97 ? 194 TYR B CE1 1 ATOM 5522 C CE2 . TYR B 1 194 ? 18.494 31.802 26.326 1.00 28.80 ? 194 TYR B CE2 1 ATOM 5523 C CZ . TYR B 1 194 ? 19.650 32.068 27.030 1.00 31.43 ? 194 TYR B CZ 1 ATOM 5524 O OH . TYR B 1 194 ? 19.643 33.074 27.969 1.00 35.29 ? 194 TYR B OH 1 ATOM 5525 N N . ALA B 1 195 ? 20.107 26.968 26.972 1.00 25.50 ? 195 ALA B N 1 ATOM 5526 C CA . ALA B 1 195 ? 19.642 26.305 28.234 1.00 25.56 ? 195 ALA B CA 1 ATOM 5527 C C . ALA B 1 195 ? 18.255 26.675 28.774 1.00 25.97 ? 195 ALA B C 1 ATOM 5528 O O . ALA B 1 195 ? 17.448 25.771 29.056 1.00 26.81 ? 195 ALA B O 1 ATOM 5529 C CB . ALA B 1 195 ? 20.712 26.395 29.353 1.00 24.68 ? 195 ALA B CB 1 ATOM 5530 N N . PRO B 1 196 ? 17.960 27.984 28.928 1.00 25.73 ? 196 PRO B N 1 ATOM 5531 C CA . PRO B 1 196 ? 16.636 28.325 29.426 1.00 25.43 ? 196 PRO B CA 1 ATOM 5532 C C . PRO B 1 196 ? 15.531 27.874 28.468 1.00 24.79 ? 196 PRO B C 1 ATOM 5533 O O . PRO B 1 196 ? 14.444 27.515 28.916 1.00 24.36 ? 196 PRO B O 1 ATOM 5534 C CB . PRO B 1 196 ? 16.659 29.862 29.523 1.00 25.75 ? 196 PRO B CB 1 ATOM 5535 C CG . PRO B 1 196 ? 18.091 30.222 29.591 1.00 26.60 ? 196 PRO B CG 1 ATOM 5536 C CD . PRO B 1 196 ? 18.813 29.178 28.775 1.00 25.92 ? 196 PRO B CD 1 ATOM 5537 N N . VAL B 1 197 ? 15.813 27.871 27.170 1.00 23.99 ? 197 VAL B N 1 ATOM 5538 C CA . VAL B 1 197 ? 14.796 27.454 26.197 1.00 23.29 ? 197 VAL B CA 1 ATOM 5539 C C . VAL B 1 197 ? 14.671 25.927 26.225 1.00 22.44 ? 197 VAL B C 1 ATOM 5540 O O . VAL B 1 197 ? 13.562 25.385 26.228 1.00 22.56 ? 197 VAL B O 1 ATOM 5541 C CB . VAL B 1 197 ? 15.094 27.966 24.762 1.00 23.09 ? 197 VAL B CB 1 ATOM 5542 C CG1 . VAL B 1 197 ? 14.113 27.321 23.735 1.00 22.44 ? 197 VAL B CG1 1 ATOM 5543 C CG2 . VAL B 1 197 ? 14.986 29.503 24.709 1.00 22.51 ? 197 VAL B CG2 1 ATOM 5544 N N . PHE B 1 198 ? 15.821 25.254 26.262 1.00 22.55 ? 198 PHE B N 1 ATOM 5545 C CA . PHE B 1 198 ? 15.862 23.811 26.348 1.00 22.42 ? 198 PHE B CA 1 ATOM 5546 C C . PHE B 1 198 ? 14.973 23.285 27.507 1.00 22.32 ? 198 PHE B C 1 ATOM 5547 O O . PHE B 1 198 ? 14.141 22.400 27.299 1.00 22.24 ? 198 PHE B O 1 ATOM 5548 C CB . PHE B 1 198 ? 17.308 23.316 26.457 1.00 22.41 ? 198 PHE B CB 1 ATOM 5549 C CG . PHE B 1 198 ? 17.415 21.831 26.557 1.00 23.65 ? 198 PHE B CG 1 ATOM 5550 C CD1 . PHE B 1 198 ? 17.204 21.027 25.432 1.00 25.81 ? 198 PHE B CD1 1 ATOM 5551 C CD2 . PHE B 1 198 ? 17.670 21.215 27.786 1.00 26.88 ? 198 PHE B CD2 1 ATOM 5552 C CE1 . PHE B 1 198 ? 17.283 19.619 25.536 1.00 26.01 ? 198 PHE B CE1 1 ATOM 5553 C CE2 . PHE B 1 198 ? 17.745 19.835 27.897 1.00 25.67 ? 198 PHE B CE2 1 ATOM 5554 C CZ . PHE B 1 198 ? 17.557 19.037 26.763 1.00 27.04 ? 198 PHE B CZ 1 ATOM 5555 N N . ARG B 1 199 ? 15.109 23.877 28.692 1.00 21.63 ? 199 ARG B N 1 ATOM 5556 C CA . ARG B 1 199 ? 14.281 23.521 29.845 1.00 21.73 ? 199 ARG B CA 1 ATOM 5557 C C . ARG B 1 199 ? 12.791 23.761 29.597 1.00 20.99 ? 199 ARG B C 1 ATOM 5558 O O . ARG B 1 199 ? 11.956 22.878 29.858 1.00 19.64 ? 199 ARG B O 1 ATOM 5559 C CB . ARG B 1 199 ? 14.729 24.292 31.106 1.00 22.13 ? 199 ARG B CB 1 ATOM 5560 C CG . ARG B 1 199 ? 15.955 23.732 31.754 1.00 23.04 ? 199 ARG B CG 1 ATOM 5561 C CD . ARG B 1 199 ? 16.380 24.588 32.964 1.00 29.08 ? 199 ARG B CD 1 ATOM 5562 N NE . ARG B 1 199 ? 17.826 24.518 32.987 1.00 31.93 ? 199 ARG B NE 1 ATOM 5563 C CZ . ARG B 1 199 ? 18.650 25.491 32.646 1.00 30.91 ? 199 ARG B CZ 1 ATOM 5564 N NH1 . ARG B 1 199 ? 18.211 26.712 32.329 1.00 31.69 ? 199 ARG B NH1 1 ATOM 5565 N NH2 . ARG B 1 199 ? 19.938 25.232 32.673 1.00 32.79 ? 199 ARG B NH2 1 ATOM 5566 N N . ASP B 1 200 ? 12.478 24.962 29.119 1.00 20.59 ? 200 ASP B N 1 ATOM 5567 C CA . ASP B 1 200 ? 11.120 25.353 28.734 1.00 21.34 ? 200 ASP B CA 1 ATOM 5568 C C . ASP B 1 200 ? 10.505 24.502 27.611 1.00 21.08 ? 200 ASP B C 1 ATOM 5569 O O . ASP B 1 200 ? 9.299 24.248 27.617 1.00 20.77 ? 200 ASP B O 1 ATOM 5570 C CB . ASP B 1 200 ? 11.106 26.813 28.290 1.00 21.78 ? 200 ASP B CB 1 ATOM 5571 C CG . ASP B 1 200 ? 11.117 27.799 29.472 1.00 26.92 ? 200 ASP B CG 1 ATOM 5572 O OD1 . ASP B 1 200 ? 11.199 27.357 30.639 1.00 27.66 ? 200 ASP B OD1 1 ATOM 5573 O OD2 . ASP B 1 200 ? 11.037 29.020 29.215 1.00 30.61 ? 200 ASP B OD2 1 ATOM 5574 N N . TYR B 1 201 ? 11.340 24.082 26.655 1.00 21.05 ? 201 TYR B N 1 ATOM 5575 C CA . TYR B 1 201 ? 10.902 23.241 25.534 1.00 19.80 ? 201 TYR B CA 1 ATOM 5576 C C . TYR B 1 201 ? 10.461 21.872 26.042 1.00 19.26 ? 201 TYR B C 1 ATOM 5577 O O . TYR B 1 201 ? 9.341 21.415 25.761 1.00 18.21 ? 201 TYR B O 1 ATOM 5578 C CB . TYR B 1 201 ? 12.029 23.083 24.504 1.00 20.53 ? 201 TYR B CB 1 ATOM 5579 C CG . TYR B 1 201 ? 11.597 22.304 23.259 1.00 21.32 ? 201 TYR B CG 1 ATOM 5580 C CD1 . TYR B 1 201 ? 11.637 20.904 23.229 1.00 22.16 ? 201 TYR B CD1 1 ATOM 5581 C CD2 . TYR B 1 201 ? 11.133 22.986 22.119 1.00 21.80 ? 201 TYR B CD2 1 ATOM 5582 C CE1 . TYR B 1 201 ? 11.211 20.187 22.091 1.00 21.28 ? 201 TYR B CE1 1 ATOM 5583 C CE2 . TYR B 1 201 ? 10.725 22.280 20.965 1.00 23.00 ? 201 TYR B CE2 1 ATOM 5584 C CZ . TYR B 1 201 ? 10.769 20.888 20.966 1.00 23.82 ? 201 TYR B CZ 1 ATOM 5585 O OH . TYR B 1 201 ? 10.340 20.214 19.839 1.00 26.16 ? 201 TYR B OH 1 ATOM 5586 N N . VAL B 1 202 ? 11.343 21.216 26.797 1.00 19.33 ? 202 VAL B N 1 ATOM 5587 C CA . VAL B 1 202 ? 11.030 19.924 27.407 1.00 19.50 ? 202 VAL B CA 1 ATOM 5588 C C . VAL B 1 202 ? 9.714 20.011 28.220 1.00 19.12 ? 202 VAL B C 1 ATOM 5589 O O . VAL B 1 202 ? 8.824 19.155 28.081 1.00 18.14 ? 202 VAL B O 1 ATOM 5590 C CB . VAL B 1 202 ? 12.232 19.426 28.271 1.00 20.41 ? 202 VAL B CB 1 ATOM 5591 C CG1 . VAL B 1 202 ? 11.917 18.119 28.997 1.00 21.44 ? 202 VAL B CG1 1 ATOM 5592 C CG2 . VAL B 1 202 ? 13.496 19.275 27.415 1.00 20.97 ? 202 VAL B CG2 1 ATOM 5593 N N . PHE B 1 203 ? 9.586 21.051 29.059 1.00 19.12 ? 203 PHE B N 1 ATOM 5594 C CA . PHE B 1 203 ? 8.365 21.234 29.864 1.00 19.09 ? 203 PHE B CA 1 ATOM 5595 C C . PHE B 1 203 ? 7.106 21.386 28.993 1.00 18.23 ? 203 PHE B C 1 ATOM 5596 O O . PHE B 1 203 ? 6.070 20.780 29.271 1.00 16.92 ? 203 PHE B O 1 ATOM 5597 C CB . PHE B 1 203 ? 8.497 22.435 30.820 1.00 18.94 ? 203 PHE B CB 1 ATOM 5598 C CG . PHE B 1 203 ? 7.484 22.437 31.957 1.00 20.75 ? 203 PHE B CG 1 ATOM 5599 C CD1 . PHE B 1 203 ? 6.260 23.099 31.829 1.00 21.62 ? 203 PHE B CD1 1 ATOM 5600 C CD2 . PHE B 1 203 ? 7.780 21.808 33.172 1.00 21.17 ? 203 PHE B CD2 1 ATOM 5601 C CE1 . PHE B 1 203 ? 5.327 23.131 32.903 1.00 22.84 ? 203 PHE B CE1 1 ATOM 5602 C CE2 . PHE B 1 203 ? 6.857 21.822 34.259 1.00 22.09 ? 203 PHE B CE2 1 ATOM 5603 C CZ . PHE B 1 203 ? 5.632 22.488 34.120 1.00 23.88 ? 203 PHE B CZ 1 ATOM 5604 N N . ARG B 1 204 ? 7.205 22.199 27.943 1.00 19.33 ? 204 ARG B N 1 ATOM 5605 C CA . ARG B 1 204 ? 6.064 22.455 27.073 1.00 19.75 ? 204 ARG B CA 1 ATOM 5606 C C . ARG B 1 204 ? 5.675 21.208 26.278 1.00 19.83 ? 204 ARG B C 1 ATOM 5607 O O . ARG B 1 204 ? 4.489 21.022 25.971 1.00 18.80 ? 204 ARG B O 1 ATOM 5608 C CB . ARG B 1 204 ? 6.341 23.615 26.109 1.00 20.29 ? 204 ARG B CB 1 ATOM 5609 C CG . ARG B 1 204 ? 5.080 24.196 25.514 1.00 24.06 ? 204 ARG B CG 1 ATOM 5610 C CD . ARG B 1 204 ? 5.366 25.395 24.663 1.00 27.00 ? 204 ARG B CD 1 ATOM 5611 N NE . ARG B 1 204 ? 4.157 25.834 23.970 1.00 31.23 ? 204 ARG B NE 1 ATOM 5612 C CZ . ARG B 1 204 ? 3.298 26.734 24.446 1.00 32.60 ? 204 ARG B CZ 1 ATOM 5613 N NH1 . ARG B 1 204 ? 3.488 27.297 25.638 1.00 29.77 ? 204 ARG B NH1 1 ATOM 5614 N NH2 . ARG B 1 204 ? 2.238 27.065 23.730 1.00 33.93 ? 204 ARG B NH2 1 ATOM 5615 N N . SER B 1 205 ? 6.662 20.377 25.925 1.00 19.35 ? 205 SER B N 1 ATOM 5616 C CA . SER B 1 205 ? 6.365 19.111 25.233 1.00 20.55 ? 205 SER B CA 1 ATOM 5617 C C . SER B 1 205 ? 5.511 18.194 26.119 1.00 20.35 ? 205 SER B C 1 ATOM 5618 O O . SER B 1 205 ? 4.542 17.586 25.640 1.00 20.04 ? 205 SER B O 1 ATOM 5619 C CB . SER B 1 205 ? 7.640 18.394 24.755 1.00 20.41 ? 205 SER B CB 1 ATOM 5620 O OG . SER B 1 205 ? 8.314 17.755 25.843 1.00 22.84 ? 205 SER B OG 1 ATOM 5621 N N . MET B 1 206 ? 5.840 18.126 27.411 1.00 19.85 ? 206 MET B N 1 ATOM 5622 C CA . MET B 1 206 ? 4.989 17.396 28.346 1.00 20.46 ? 206 MET B CA 1 ATOM 5623 C C . MET B 1 206 ? 3.594 18.033 28.490 1.00 20.24 ? 206 MET B C 1 ATOM 5624 O O . MET B 1 206 ? 2.629 17.304 28.534 1.00 20.65 ? 206 MET B O 1 ATOM 5625 C CB . MET B 1 206 ? 5.668 17.151 29.712 1.00 20.48 ? 206 MET B CB 1 ATOM 5626 C CG . MET B 1 206 ? 6.879 16.235 29.622 1.00 20.31 ? 206 MET B CG 1 ATOM 5627 S SD . MET B 1 206 ? 7.733 16.093 31.214 1.00 21.99 ? 206 MET B SD 1 ATOM 5628 C CE . MET B 1 206 ? 8.547 17.691 31.335 1.00 17.00 ? 206 MET B CE 1 ATOM 5629 N N . GLN B 1 207 ? 3.494 19.366 28.545 1.00 20.43 ? 207 GLN B N 1 ATOM 5630 C CA . GLN B 1 207 ? 2.182 20.046 28.605 1.00 21.45 ? 207 GLN B CA 1 ATOM 5631 C C . GLN B 1 207 ? 1.268 19.705 27.435 1.00 21.09 ? 207 GLN B C 1 ATOM 5632 O O . GLN B 1 207 ? 0.094 19.412 27.645 1.00 21.02 ? 207 GLN B O 1 ATOM 5633 C CB . GLN B 1 207 ? 2.325 21.564 28.629 1.00 21.68 ? 207 GLN B CB 1 ATOM 5634 C CG . GLN B 1 207 ? 2.955 22.132 29.903 1.00 24.33 ? 207 GLN B CG 1 ATOM 5635 C CD . GLN B 1 207 ? 3.077 23.634 29.840 1.00 25.63 ? 207 GLN B CD 1 ATOM 5636 O OE1 . GLN B 1 207 ? 3.928 24.188 29.122 1.00 28.53 ? 207 GLN B OE1 1 ATOM 5637 N NE2 . GLN B 1 207 ? 2.241 24.308 30.601 1.00 25.28 ? 207 GLN B NE2 1 ATOM 5638 N N . GLU B 1 208 ? 1.800 19.801 26.208 1.00 20.58 ? 208 GLU B N 1 ATOM 5639 C CA . GLU B 1 208 ? 1.057 19.428 24.992 1.00 20.97 ? 208 GLU B CA 1 ATOM 5640 C C . GLU B 1 208 ? 0.568 17.986 24.980 1.00 20.10 ? 208 GLU B C 1 ATOM 5641 O O . GLU B 1 208 ? -0.619 17.743 24.693 1.00 19.64 ? 208 GLU B O 1 ATOM 5642 C CB . GLU B 1 208 ? 1.857 19.744 23.717 1.00 21.57 ? 208 GLU B CB 1 ATOM 5643 C CG . GLU B 1 208 ? 1.848 21.224 23.387 1.00 27.48 ? 208 GLU B CG 1 ATOM 5644 C CD . GLU B 1 208 ? 2.622 21.576 22.125 1.00 32.77 ? 208 GLU B CD 1 ATOM 5645 O OE1 . GLU B 1 208 ? 2.451 20.916 21.085 1.00 38.72 ? 208 GLU B OE1 1 ATOM 5646 O OE2 . GLU B 1 208 ? 3.413 22.530 22.171 1.00 38.28 ? 208 GLU B OE2 1 ATOM 5647 N N . PHE B 1 209 ? 1.434 17.021 25.326 1.00 18.47 ? 209 PHE B N 1 ATOM 5648 C CA . PHE B 1 209 ? 0.968 15.634 25.344 1.00 18.20 ? 209 PHE B CA 1 ATOM 5649 C C . PHE B 1 209 ? -0.051 15.370 26.454 1.00 18.66 ? 209 PHE B C 1 ATOM 5650 O O . PHE B 1 209 ? -1.049 14.677 26.238 1.00 18.66 ? 209 PHE B O 1 ATOM 5651 C CB . PHE B 1 209 ? 2.135 14.623 25.336 1.00 17.47 ? 209 PHE B CB 1 ATOM 5652 C CG . PHE B 1 209 ? 2.718 14.395 23.953 1.00 17.00 ? 209 PHE B CG 1 ATOM 5653 C CD1 . PHE B 1 209 ? 2.403 13.237 23.235 1.00 18.65 ? 209 PHE B CD1 1 ATOM 5654 C CD2 . PHE B 1 209 ? 3.542 15.353 23.358 1.00 17.40 ? 209 PHE B CD2 1 ATOM 5655 C CE1 . PHE B 1 209 ? 2.911 13.011 21.952 1.00 18.31 ? 209 PHE B CE1 1 ATOM 5656 C CE2 . PHE B 1 209 ? 4.049 15.154 22.035 1.00 17.87 ? 209 PHE B CE2 1 ATOM 5657 C CZ . PHE B 1 209 ? 3.725 13.980 21.342 1.00 15.29 ? 209 PHE B CZ 1 ATOM 5658 N N . TYR B 1 210 ? 0.184 15.961 27.626 1.00 19.48 ? 210 TYR B N 1 ATOM 5659 C CA . TYR B 1 210 ? -0.738 15.850 28.747 1.00 19.98 ? 210 TYR B CA 1 ATOM 5660 C C . TYR B 1 210 ? -2.141 16.360 28.394 1.00 20.49 ? 210 TYR B C 1 ATOM 5661 O O . TYR B 1 210 ? -3.138 15.726 28.732 1.00 20.55 ? 210 TYR B O 1 ATOM 5662 C CB . TYR B 1 210 ? -0.181 16.636 29.952 1.00 20.14 ? 210 TYR B CB 1 ATOM 5663 C CG . TYR B 1 210 ? -1.039 16.515 31.188 1.00 19.78 ? 210 TYR B CG 1 ATOM 5664 C CD1 . TYR B 1 210 ? -1.029 15.341 31.946 1.00 20.51 ? 210 TYR B CD1 1 ATOM 5665 C CD2 . TYR B 1 210 ? -1.865 17.556 31.594 1.00 22.40 ? 210 TYR B CD2 1 ATOM 5666 C CE1 . TYR B 1 210 ? -1.808 15.203 33.083 1.00 22.48 ? 210 TYR B CE1 1 ATOM 5667 C CE2 . TYR B 1 210 ? -2.672 17.431 32.777 1.00 23.65 ? 210 TYR B CE2 1 ATOM 5668 C CZ . TYR B 1 210 ? -2.620 16.250 33.497 1.00 24.45 ? 210 TYR B CZ 1 ATOM 5669 O OH . TYR B 1 210 ? -3.367 16.080 34.636 1.00 28.28 ? 210 TYR B OH 1 ATOM 5670 N N . GLU B 1 211 ? -2.191 17.499 27.717 1.00 21.64 ? 211 GLU B N 1 ATOM 5671 C CA . GLU B 1 211 ? -3.429 18.111 27.236 1.00 23.44 ? 211 GLU B CA 1 ATOM 5672 C C . GLU B 1 211 ? -4.146 17.175 26.256 1.00 23.57 ? 211 GLU B C 1 ATOM 5673 O O . GLU B 1 211 ? -5.392 17.149 26.192 1.00 23.18 ? 211 GLU B O 1 ATOM 5674 C CB . GLU B 1 211 ? -3.088 19.458 26.582 1.00 23.83 ? 211 GLU B CB 1 ATOM 5675 C CG . GLU B 1 211 ? -4.260 20.393 26.275 1.00 28.70 ? 211 GLU B CG 1 ATOM 5676 C CD . GLU B 1 211 ? -4.973 20.092 24.945 1.00 35.76 ? 211 GLU B CD 1 ATOM 5677 O OE1 . GLU B 1 211 ? -4.374 19.477 24.025 1.00 38.61 ? 211 GLU B OE1 1 ATOM 5678 O OE2 . GLU B 1 211 ? -6.164 20.465 24.817 1.00 38.58 ? 211 GLU B OE2 1 ATOM 5679 N N . ASP B 1 212 ? -3.353 16.378 25.528 1.00 23.10 ? 212 ASP B N 1 ATOM 5680 C CA . ASP B 1 212 ? -3.867 15.400 24.575 1.00 22.44 ? 212 ASP B CA 1 ATOM 5681 C C . ASP B 1 212 ? -4.144 14.062 25.269 1.00 22.12 ? 212 ASP B C 1 ATOM 5682 O O . ASP B 1 212 ? -4.399 13.058 24.613 1.00 22.36 ? 212 ASP B O 1 ATOM 5683 C CB . ASP B 1 212 ? -2.855 15.233 23.417 1.00 22.41 ? 212 ASP B CB 1 ATOM 5684 C CG . ASP B 1 212 ? -3.486 14.680 22.127 1.00 22.86 ? 212 ASP B CG 1 ATOM 5685 O OD1 . ASP B 1 212 ? -4.547 15.196 21.689 1.00 22.36 ? 212 ASP B OD1 1 ATOM 5686 O OD2 . ASP B 1 212 ? -2.889 13.743 21.536 1.00 18.06 ? 212 ASP B OD2 1 ATOM 5687 N N . ASN B 1 213 ? -4.075 14.044 26.602 1.00 21.90 ? 213 ASN B N 1 ATOM 5688 C CA . ASN B 1 213 ? -4.406 12.846 27.399 1.00 21.54 ? 213 ASN B CA 1 ATOM 5689 C C . ASN B 1 213 ? -3.434 11.677 27.130 1.00 20.89 ? 213 ASN B C 1 ATOM 5690 O O . ASN B 1 213 ? -3.849 10.515 27.016 1.00 20.95 ? 213 ASN B O 1 ATOM 5691 C CB . ASN B 1 213 ? -5.901 12.437 27.233 1.00 22.48 ? 213 ASN B CB 1 ATOM 5692 C CG . ASN B 1 213 ? -6.494 11.781 28.504 1.00 25.15 ? 213 ASN B CG 1 ATOM 5693 O OD1 . ASN B 1 213 ? -5.781 11.456 29.467 1.00 27.20 ? 213 ASN B OD1 1 ATOM 5694 N ND2 . ASN B 1 213 ? -7.808 11.595 28.504 1.00 28.27 ? 213 ASN B ND2 1 ATOM 5695 N N . VAL B 1 214 ? -2.139 12.025 27.061 1.00 19.26 ? 214 VAL B N 1 ATOM 5696 C CA . VAL B 1 214 ? -1.000 11.092 27.017 1.00 18.32 ? 214 VAL B CA 1 ATOM 5697 C C . VAL B 1 214 ? -0.199 11.298 28.308 1.00 17.64 ? 214 VAL B C 1 ATOM 5698 O O . VAL B 1 214 ? 0.118 12.432 28.693 1.00 18.27 ? 214 VAL B O 1 ATOM 5699 C CB . VAL B 1 214 ? -0.074 11.410 25.778 1.00 17.39 ? 214 VAL B CB 1 ATOM 5700 C CG1 . VAL B 1 214 ? 1.189 10.511 25.760 1.00 16.45 ? 214 VAL B CG1 1 ATOM 5701 C CG2 . VAL B 1 214 ? -0.866 11.266 24.474 1.00 18.28 ? 214 VAL B CG2 1 ATOM 5702 N N . LEU B 1 215 ? 0.121 10.217 28.995 1.00 16.87 ? 215 LEU B N 1 ATOM 5703 C CA . LEU B 1 215 ? 0.686 10.349 30.336 1.00 17.26 ? 215 LEU B CA 1 ATOM 5704 C C . LEU B 1 215 ? 2.151 9.920 30.476 1.00 16.64 ? 215 LEU B C 1 ATOM 5705 O O . LEU B 1 215 ? 2.707 9.941 31.574 1.00 15.19 ? 215 LEU B O 1 ATOM 5706 C CB . LEU B 1 215 ? -0.177 9.581 31.327 1.00 18.39 ? 215 LEU B CB 1 ATOM 5707 C CG . LEU B 1 215 ? -1.594 10.143 31.420 1.00 18.83 ? 215 LEU B CG 1 ATOM 5708 C CD1 . LEU B 1 215 ? -2.440 9.205 32.276 1.00 21.65 ? 215 LEU B CD1 1 ATOM 5709 C CD2 . LEU B 1 215 ? -1.544 11.517 31.999 1.00 19.66 ? 215 LEU B CD2 1 ATOM 5710 N N . TYR B 1 216 ? 2.787 9.546 29.366 1.00 15.75 ? 216 TYR B N 1 ATOM 5711 C CA . TYR B 1 216 ? 4.178 9.048 29.459 1.00 15.00 ? 216 TYR B CA 1 ATOM 5712 C C . TYR B 1 216 ? 4.816 9.188 28.102 1.00 14.98 ? 216 TYR B C 1 ATOM 5713 O O . TYR B 1 216 ? 4.121 8.987 27.097 1.00 15.27 ? 216 TYR B O 1 ATOM 5714 C CB . TYR B 1 216 ? 4.183 7.564 29.910 1.00 15.05 ? 216 TYR B CB 1 ATOM 5715 C CG . TYR B 1 216 ? 5.550 6.905 29.899 1.00 15.90 ? 216 TYR B CG 1 ATOM 5716 C CD1 . TYR B 1 216 ? 6.542 7.295 30.807 1.00 17.49 ? 216 TYR B CD1 1 ATOM 5717 C CD2 . TYR B 1 216 ? 5.856 5.888 28.993 1.00 16.13 ? 216 TYR B CD2 1 ATOM 5718 C CE1 . TYR B 1 216 ? 7.832 6.696 30.801 1.00 16.39 ? 216 TYR B CE1 1 ATOM 5719 C CE2 . TYR B 1 216 ? 7.152 5.286 28.981 1.00 17.56 ? 216 TYR B CE2 1 ATOM 5720 C CZ . TYR B 1 216 ? 8.117 5.690 29.893 1.00 16.35 ? 216 TYR B CZ 1 ATOM 5721 O OH . TYR B 1 216 ? 9.392 5.099 29.882 1.00 16.26 ? 216 TYR B OH 1 ATOM 5722 N N . MET B 1 217 ? 6.109 9.555 28.058 1.00 14.84 ? 217 MET B N 1 ATOM 5723 C CA . MET B 1 217 ? 6.826 9.698 26.780 1.00 15.93 ? 217 MET B CA 1 ATOM 5724 C C . MET B 1 217 ? 8.207 9.050 26.818 1.00 15.30 ? 217 MET B C 1 ATOM 5725 O O . MET B 1 217 ? 8.941 9.193 27.795 1.00 15.88 ? 217 MET B O 1 ATOM 5726 C CB . MET B 1 217 ? 7.002 11.193 26.401 1.00 16.21 ? 217 MET B CB 1 ATOM 5727 C CG . MET B 1 217 ? 5.683 12.004 26.338 1.00 18.80 ? 217 MET B CG 1 ATOM 5728 S SD . MET B 1 217 ? 5.862 13.786 26.620 1.00 21.04 ? 217 MET B SD 1 ATOM 5729 C CE . MET B 1 217 ? 4.268 14.088 27.307 1.00 29.83 ? 217 MET B CE 1 ATOM 5730 N N . GLU B 1 218 ? 8.555 8.358 25.742 1.00 15.51 ? 218 GLU B N 1 ATOM 5731 C CA . GLU B 1 218 ? 9.937 7.980 25.467 1.00 16.23 ? 218 GLU B CA 1 ATOM 5732 C C . GLU B 1 218 ? 10.406 8.704 24.193 1.00 17.03 ? 218 GLU B C 1 ATOM 5733 O O . GLU B 1 218 ? 9.742 8.645 23.144 1.00 15.94 ? 218 GLU B O 1 ATOM 5734 C CB . GLU B 1 218 ? 10.084 6.449 25.349 1.00 16.09 ? 218 GLU B CB 1 ATOM 5735 C CG . GLU B 1 218 ? 9.670 5.747 26.677 1.00 16.15 ? 218 GLU B CG 1 ATOM 5736 C CD . GLU B 1 218 ? 9.916 4.218 26.727 1.00 15.96 ? 218 GLU B CD 1 ATOM 5737 O OE1 . GLU B 1 218 ? 10.159 3.568 25.686 1.00 16.67 ? 218 GLU B OE1 1 ATOM 5738 O OE2 . GLU B 1 218 ? 9.806 3.654 27.832 1.00 16.94 ? 218 GLU B OE2 1 ATOM 5739 N N . ILE B 1 219 ? 11.554 9.372 24.316 1.00 17.03 ? 219 ILE B N 1 ATOM 5740 C CA . ILE B 1 219 ? 12.072 10.302 23.328 1.00 17.22 ? 219 ILE B CA 1 ATOM 5741 C C . ILE B 1 219 ? 13.436 9.827 22.817 1.00 17.62 ? 219 ILE B C 1 ATOM 5742 O O . ILE B 1 219 ? 14.336 9.532 23.629 1.00 17.65 ? 219 ILE B O 1 ATOM 5743 C CB . ILE B 1 219 ? 12.212 11.705 23.985 1.00 17.46 ? 219 ILE B CB 1 ATOM 5744 C CG1 . ILE B 1 219 ? 10.867 12.149 24.577 1.00 16.32 ? 219 ILE B CG1 1 ATOM 5745 C CG2 . ILE B 1 219 ? 12.719 12.742 22.989 1.00 19.25 ? 219 ILE B CG2 1 ATOM 5746 C CD1 . ILE B 1 219 ? 10.957 13.205 25.665 1.00 19.78 ? 219 ILE B CD1 1 ATOM 5747 N N . ARG B 1 220 ? 13.573 9.703 21.491 1.00 17.59 ? 220 ARG B N 1 ATOM 5748 C CA . ARG B 1 220 ? 14.900 9.568 20.857 1.00 18.15 ? 220 ARG B CA 1 ATOM 5749 C C . ARG B 1 220 ? 15.540 10.933 20.909 1.00 18.32 ? 220 ARG B C 1 ATOM 5750 O O . ARG B 1 220 ? 14.989 11.893 20.378 1.00 18.57 ? 220 ARG B O 1 ATOM 5751 C CB . ARG B 1 220 ? 14.796 9.167 19.382 1.00 18.08 ? 220 ARG B CB 1 ATOM 5752 C CG . ARG B 1 220 ? 14.887 7.676 19.089 1.00 19.31 ? 220 ARG B CG 1 ATOM 5753 C CD . ARG B 1 220 ? 13.695 6.876 19.578 1.00 18.19 ? 220 ARG B CD 1 ATOM 5754 N NE . ARG B 1 220 ? 13.615 5.589 18.866 1.00 16.82 ? 220 ARG B NE 1 ATOM 5755 C CZ . ARG B 1 220 ? 12.561 4.779 18.878 1.00 17.22 ? 220 ARG B CZ 1 ATOM 5756 N NH1 . ARG B 1 220 ? 11.467 5.108 19.589 1.00 14.47 ? 220 ARG B NH1 1 ATOM 5757 N NH2 . ARG B 1 220 ? 12.605 3.642 18.178 1.00 14.90 ? 220 ARG B NH2 1 ATOM 5758 N N . ALA B 1 221 ? 16.707 11.019 21.531 1.00 17.96 ? 221 ALA B N 1 ATOM 5759 C CA . ALA B 1 221 ? 17.311 12.307 21.788 1.00 18.31 ? 221 ALA B CA 1 ATOM 5760 C C . ALA B 1 221 ? 18.756 12.237 21.381 1.00 18.77 ? 221 ALA B C 1 ATOM 5761 O O . ALA B 1 221 ? 19.466 11.343 21.827 1.00 17.75 ? 221 ALA B O 1 ATOM 5762 C CB . ALA B 1 221 ? 17.199 12.654 23.260 1.00 17.42 ? 221 ALA B CB 1 ATOM 5763 N N . ARG B 1 222 ? 19.173 13.176 20.534 1.00 19.61 ? 222 ARG B N 1 ATOM 5764 C CA . ARG B 1 222 ? 20.563 13.252 20.041 1.00 21.00 ? 222 ARG B CA 1 ATOM 5765 C C . ARG B 1 222 ? 21.514 13.746 21.149 1.00 21.51 ? 222 ARG B C 1 ATOM 5766 O O . ARG B 1 222 ? 22.735 13.540 21.084 1.00 21.14 ? 222 ARG B O 1 ATOM 5767 C CB . ARG B 1 222 ? 20.648 14.183 18.838 1.00 20.31 ? 222 ARG B CB 1 ATOM 5768 C CG . ARG B 1 222 ? 19.940 13.678 17.555 1.00 23.95 ? 222 ARG B CG 1 ATOM 5769 C CD . ARG B 1 222 ? 20.686 12.525 16.871 1.00 24.15 ? 222 ARG B CD 1 ATOM 5770 N NE . ARG B 1 222 ? 22.060 12.903 16.528 1.00 28.02 ? 222 ARG B NE 1 ATOM 5771 C CZ . ARG B 1 222 ? 22.418 13.697 15.514 1.00 27.80 ? 222 ARG B CZ 1 ATOM 5772 N NH1 . ARG B 1 222 ? 21.526 14.204 14.694 1.00 27.78 ? 222 ARG B NH1 1 ATOM 5773 N NH2 . ARG B 1 222 ? 23.695 13.967 15.315 1.00 31.24 ? 222 ARG B NH2 1 ATOM 5774 N N . LEU B 1 223 ? 20.931 14.369 22.174 1.00 21.68 ? 223 LEU B N 1 ATOM 5775 C CA . LEU B 1 223 ? 21.692 14.941 23.276 1.00 22.93 ? 223 LEU B CA 1 ATOM 5776 C C . LEU B 1 223 ? 22.789 15.867 22.748 1.00 23.16 ? 223 LEU B C 1 ATOM 5777 O O . LEU B 1 223 ? 23.948 15.748 23.145 1.00 23.41 ? 223 LEU B O 1 ATOM 5778 C CB . LEU B 1 223 ? 22.277 13.839 24.204 1.00 23.45 ? 223 LEU B CB 1 ATOM 5779 C CG . LEU B 1 223 ? 21.286 12.905 24.927 1.00 24.07 ? 223 LEU B CG 1 ATOM 5780 C CD1 . LEU B 1 223 ? 22.027 11.921 25.820 1.00 23.84 ? 223 LEU B CD1 1 ATOM 5781 C CD2 . LEU B 1 223 ? 20.232 13.720 25.731 1.00 23.49 ? 223 LEU B CD2 1 ATOM 5782 N N . LEU B 1 224 ? 22.413 16.791 21.865 1.00 24.15 ? 224 LEU B N 1 ATOM 5783 C CA . LEU B 1 224 ? 23.361 17.755 21.287 1.00 25.13 ? 224 LEU B CA 1 ATOM 5784 C C . LEU B 1 224 ? 23.749 18.759 22.366 1.00 25.28 ? 224 LEU B C 1 ATOM 5785 O O . LEU B 1 224 ? 22.979 18.957 23.302 1.00 25.09 ? 224 LEU B O 1 ATOM 5786 C CB . LEU B 1 224 ? 22.737 18.487 20.088 1.00 25.18 ? 224 LEU B CB 1 ATOM 5787 C CG . LEU B 1 224 ? 23.031 18.068 18.629 1.00 27.61 ? 224 LEU B CG 1 ATOM 5788 C CD1 . LEU B 1 224 ? 23.382 16.604 18.446 1.00 25.92 ? 224 LEU B CD1 1 ATOM 5789 C CD2 . LEU B 1 224 ? 21.868 18.508 17.695 1.00 26.51 ? 224 LEU B CD2 1 ATOM 5790 N N . PRO B 1 225 ? 24.939 19.388 22.247 1.00 25.79 ? 225 PRO B N 1 ATOM 5791 C CA . PRO B 1 225 ? 25.372 20.291 23.338 1.00 25.96 ? 225 PRO B CA 1 ATOM 5792 C C . PRO B 1 225 ? 24.399 21.435 23.602 1.00 25.47 ? 225 PRO B C 1 ATOM 5793 O O . PRO B 1 225 ? 23.979 22.118 22.676 1.00 25.63 ? 225 PRO B O 1 ATOM 5794 C CB . PRO B 1 225 ? 26.741 20.797 22.858 1.00 25.99 ? 225 PRO B CB 1 ATOM 5795 C CG . PRO B 1 225 ? 27.271 19.634 21.989 1.00 26.41 ? 225 PRO B CG 1 ATOM 5796 C CD . PRO B 1 225 ? 26.030 19.117 21.280 1.00 25.49 ? 225 PRO B CD 1 ATOM 5797 N N . VAL B 1 226 ? 24.006 21.594 24.863 1.00 25.78 ? 226 VAL B N 1 ATOM 5798 C CA . VAL B 1 226 ? 23.161 22.718 25.281 1.00 25.69 ? 226 VAL B CA 1 ATOM 5799 C C . VAL B 1 226 ? 24.100 23.823 25.782 1.00 26.33 ? 226 VAL B C 1 ATOM 5800 O O . VAL B 1 226 ? 25.139 23.545 26.396 1.00 25.86 ? 226 VAL B O 1 ATOM 5801 C CB . VAL B 1 226 ? 22.089 22.310 26.354 1.00 25.81 ? 226 VAL B CB 1 ATOM 5802 C CG1 . VAL B 1 226 ? 21.417 23.543 26.987 1.00 24.35 ? 226 VAL B CG1 1 ATOM 5803 C CG2 . VAL B 1 226 ? 21.017 21.393 25.726 1.00 23.69 ? 226 VAL B CG2 1 ATOM 5804 N N . TYR B 1 227 ? 23.749 25.067 25.484 1.00 27.02 ? 227 TYR B N 1 ATOM 5805 C CA . TYR B 1 227 ? 24.698 26.160 25.655 1.00 28.72 ? 227 TYR B CA 1 ATOM 5806 C C . TYR B 1 227 ? 24.115 27.343 26.450 1.00 29.27 ? 227 TYR B C 1 ATOM 5807 O O . TYR B 1 227 ? 22.902 27.482 26.591 1.00 29.52 ? 227 TYR B O 1 ATOM 5808 C CB . TYR B 1 227 ? 25.301 26.592 24.293 1.00 28.02 ? 227 TYR B CB 1 ATOM 5809 C CG . TYR B 1 227 ? 24.332 27.337 23.416 1.00 28.27 ? 227 TYR B CG 1 ATOM 5810 C CD1 . TYR B 1 227 ? 24.234 28.739 23.478 1.00 27.26 ? 227 TYR B CD1 1 ATOM 5811 C CD2 . TYR B 1 227 ? 23.502 26.652 22.521 1.00 27.81 ? 227 TYR B CD2 1 ATOM 5812 C CE1 . TYR B 1 227 ? 23.334 29.433 22.684 1.00 27.69 ? 227 TYR B CE1 1 ATOM 5813 C CE2 . TYR B 1 227 ? 22.596 27.340 21.717 1.00 28.02 ? 227 TYR B CE2 1 ATOM 5814 C CZ . TYR B 1 227 ? 22.516 28.722 21.802 1.00 27.61 ? 227 TYR B CZ 1 ATOM 5815 O OH . TYR B 1 227 ? 21.625 29.388 21.013 1.00 28.85 ? 227 TYR B OH 1 ATOM 5816 N N . GLU B 1 228 ? 25.015 28.166 26.980 1.00 31.27 ? 228 GLU B N 1 ATOM 5817 C CA . GLU B 1 228 ? 24.684 29.317 27.822 1.00 32.25 ? 228 GLU B CA 1 ATOM 5818 C C . GLU B 1 228 ? 24.946 30.615 27.052 1.00 33.65 ? 228 GLU B C 1 ATOM 5819 O O . GLU B 1 228 ? 25.683 30.598 26.054 1.00 34.13 ? 228 GLU B O 1 ATOM 5820 C CB . GLU B 1 228 ? 25.537 29.274 29.097 1.00 32.39 ? 228 GLU B CB 1 ATOM 5821 C CG . GLU B 1 228 ? 25.349 28.032 29.995 1.00 29.83 ? 228 GLU B CG 1 ATOM 5822 C CD . GLU B 1 228 ? 23.949 27.918 30.623 1.00 29.96 ? 228 GLU B CD 1 ATOM 5823 O OE1 . GLU B 1 228 ? 23.202 28.911 30.648 1.00 31.39 ? 228 GLU B OE1 1 ATOM 5824 O OE2 . GLU B 1 228 ? 23.588 26.815 31.109 1.00 31.19 ? 228 GLU B OE2 1 ATOM 5825 N N . LEU B 1 229 ? 24.368 31.731 27.508 1.00 34.77 ? 229 LEU B N 1 ATOM 5826 C CA . LEU B 1 229 ? 24.576 33.052 26.864 1.00 36.24 ? 229 LEU B CA 1 ATOM 5827 C C . LEU B 1 229 ? 26.046 33.361 26.625 1.00 36.75 ? 229 LEU B C 1 ATOM 5828 O O . LEU B 1 229 ? 26.413 33.925 25.594 1.00 37.68 ? 229 LEU B O 1 ATOM 5829 C CB . LEU B 1 229 ? 23.959 34.197 27.679 1.00 35.88 ? 229 LEU B CB 1 ATOM 5830 C CG . LEU B 1 229 ? 22.524 34.653 27.429 1.00 36.40 ? 229 LEU B CG 1 ATOM 5831 C CD1 . LEU B 1 229 ? 22.200 35.867 28.275 1.00 34.79 ? 229 LEU B CD1 1 ATOM 5832 C CD2 . LEU B 1 229 ? 22.257 34.937 25.951 1.00 36.21 ? 229 LEU B CD2 1 ATOM 5833 N N . SER B 1 230 ? 26.876 32.964 27.580 1.00 37.59 ? 230 SER B N 1 ATOM 5834 C CA . SER B 1 230 ? 28.314 33.199 27.564 1.00 38.16 ? 230 SER B CA 1 ATOM 5835 C C . SER B 1 230 ? 29.062 32.400 26.507 1.00 38.43 ? 230 SER B C 1 ATOM 5836 O O . SER B 1 230 ? 30.243 32.636 26.279 1.00 38.53 ? 230 SER B O 1 ATOM 5837 C CB . SER B 1 230 ? 28.880 32.824 28.927 1.00 38.47 ? 230 SER B CB 1 ATOM 5838 O OG . SER B 1 230 ? 28.674 31.443 29.174 1.00 39.69 ? 230 SER B OG 1 ATOM 5839 N N . GLY B 1 231 ? 28.391 31.428 25.893 1.00 38.77 ? 231 GLY B N 1 ATOM 5840 C CA . GLY B 1 231 ? 29.047 30.527 24.951 1.00 38.74 ? 231 GLY B CA 1 ATOM 5841 C C . GLY B 1 231 ? 29.470 29.176 25.508 1.00 38.86 ? 231 GLY B C 1 ATOM 5842 O O . GLY B 1 231 ? 29.849 28.290 24.741 1.00 39.03 ? 231 GLY B O 1 ATOM 5843 N N . GLU B 1 232 ? 29.419 29.015 26.830 1.00 38.51 ? 232 GLU B N 1 ATOM 5844 C CA . GLU B 1 232 ? 29.712 27.714 27.482 1.00 38.60 ? 232 GLU B CA 1 ATOM 5845 C C . GLU B 1 232 ? 28.781 26.595 26.970 1.00 37.86 ? 232 GLU B C 1 ATOM 5846 O O . GLU B 1 232 ? 27.584 26.832 26.798 1.00 37.89 ? 232 GLU B O 1 ATOM 5847 C CB . GLU B 1 232 ? 29.558 27.845 29.009 1.00 38.69 ? 232 GLU B CB 1 ATOM 5848 C CG . GLU B 1 232 ? 29.869 26.570 29.791 1.00 40.87 ? 232 GLU B CG 1 ATOM 5849 C CD . GLU B 1 232 ? 29.315 26.547 31.231 1.00 42.40 ? 232 GLU B CD 1 ATOM 5850 O OE1 . GLU B 1 232 ? 29.016 27.614 31.826 1.00 42.42 ? 232 GLU B OE1 1 ATOM 5851 O OE2 . GLU B 1 232 ? 29.194 25.427 31.774 1.00 43.57 ? 232 GLU B OE2 1 ATOM 5852 N N . HIS B 1 233 ? 29.332 25.400 26.741 1.00 37.24 ? 233 HIS B N 1 ATOM 5853 C CA . HIS B 1 233 ? 28.558 24.219 26.305 1.00 36.84 ? 233 HIS B CA 1 ATOM 5854 C C . HIS B 1 233 ? 28.513 23.134 27.387 1.00 35.05 ? 233 HIS B C 1 ATOM 5855 O O . HIS B 1 233 ? 29.513 22.886 28.060 1.00 34.78 ? 233 HIS B O 1 ATOM 5856 C CB . HIS B 1 233 ? 29.155 23.613 25.022 1.00 37.97 ? 233 HIS B CB 1 ATOM 5857 C CG . HIS B 1 233 ? 29.281 24.589 23.894 1.00 42.48 ? 233 HIS B CG 1 ATOM 5858 N ND1 . HIS B 1 233 ? 28.192 25.037 23.168 1.00 47.42 ? 233 HIS B ND1 1 ATOM 5859 C CD2 . HIS B 1 233 ? 30.362 25.222 23.375 1.00 46.14 ? 233 HIS B CD2 1 ATOM 5860 C CE1 . HIS B 1 233 ? 28.597 25.897 22.248 1.00 47.05 ? 233 HIS B CE1 1 ATOM 5861 N NE2 . HIS B 1 233 ? 29.909 26.029 22.355 1.00 48.76 ? 233 HIS B NE2 1 ATOM 5862 N N . HIS B 1 234 ? 27.361 22.479 27.540 1.00 32.73 ? 234 HIS B N 1 ATOM 5863 C CA . HIS B 1 234 ? 27.225 21.328 28.446 1.00 30.44 ? 234 HIS B CA 1 ATOM 5864 C C . HIS B 1 234 ? 27.355 20.002 27.694 1.00 29.61 ? 234 HIS B C 1 ATOM 5865 O O . HIS B 1 234 ? 27.339 19.990 26.472 1.00 28.84 ? 234 HIS B O 1 ATOM 5866 C CB . HIS B 1 234 ? 25.879 21.368 29.162 1.00 30.62 ? 234 HIS B CB 1 ATOM 5867 C CG . HIS B 1 234 ? 25.656 22.610 29.962 1.00 29.42 ? 234 HIS B CG 1 ATOM 5868 N ND1 . HIS B 1 234 ? 26.377 22.901 31.095 1.00 31.63 ? 234 HIS B ND1 1 ATOM 5869 C CD2 . HIS B 1 234 ? 24.790 23.634 29.798 1.00 31.40 ? 234 HIS B CD2 1 ATOM 5870 C CE1 . HIS B 1 234 ? 25.972 24.053 31.595 1.00 31.08 ? 234 HIS B CE1 1 ATOM 5871 N NE2 . HIS B 1 234 ? 25.006 24.519 30.828 1.00 32.57 ? 234 HIS B NE2 1 ATOM 5872 N N . ASP B 1 235 ? 27.449 18.885 28.415 1.00 28.14 ? 235 ASP B N 1 ATOM 5873 C CA . ASP B 1 235 ? 27.600 17.571 27.776 1.00 28.31 ? 235 ASP B CA 1 ATOM 5874 C C . ASP B 1 235 ? 26.338 16.655 27.844 1.00 27.80 ? 235 ASP B C 1 ATOM 5875 O O . ASP B 1 235 ? 25.258 17.103 28.255 1.00 27.00 ? 235 ASP B O 1 ATOM 5876 C CB . ASP B 1 235 ? 28.836 16.855 28.342 1.00 28.11 ? 235 ASP B CB 1 ATOM 5877 C CG . ASP B 1 235 ? 28.678 16.480 29.804 1.00 29.72 ? 235 ASP B CG 1 ATOM 5878 O OD1 . ASP B 1 235 ? 27.625 16.808 30.434 1.00 27.16 ? 235 ASP B OD1 1 ATOM 5879 O OD2 . ASP B 1 235 ? 29.623 15.840 30.327 1.00 29.62 ? 235 ASP B OD2 1 ATOM 5880 N N . GLU B 1 236 ? 26.491 15.393 27.421 1.00 27.06 ? 236 GLU B N 1 ATOM 5881 C CA . GLU B 1 236 ? 25.376 14.426 27.353 1.00 27.28 ? 236 GLU B CA 1 ATOM 5882 C C . GLU B 1 236 ? 24.808 14.131 28.730 1.00 27.22 ? 236 GLU B C 1 ATOM 5883 O O . GLU B 1 236 ? 23.598 14.060 28.904 1.00 27.02 ? 236 GLU B O 1 ATOM 5884 C CB . GLU B 1 236 ? 25.791 13.105 26.701 1.00 26.25 ? 236 GLU B CB 1 ATOM 5885 C CG . GLU B 1 236 ? 26.100 13.207 25.218 1.00 26.69 ? 236 GLU B CG 1 ATOM 5886 C CD . GLU B 1 236 ? 27.536 13.645 24.939 1.00 27.57 ? 236 GLU B CD 1 ATOM 5887 O OE1 . GLU B 1 236 ? 28.268 13.995 25.889 1.00 25.33 ? 236 GLU B OE1 1 ATOM 5888 O OE2 . GLU B 1 236 ? 27.923 13.639 23.756 1.00 28.89 ? 236 GLU B OE2 1 ATOM 5889 N N . GLU B 1 237 ? 25.699 13.959 29.692 1.00 26.91 ? 237 GLU B N 1 ATOM 5890 C CA . GLU B 1 237 ? 25.334 13.690 31.077 1.00 27.76 ? 237 GLU B CA 1 ATOM 5891 C C . GLU B 1 237 ? 24.448 14.816 31.621 1.00 26.45 ? 237 GLU B C 1 ATOM 5892 O O . GLU B 1 237 ? 23.438 14.570 32.295 1.00 27.13 ? 237 GLU B O 1 ATOM 5893 C CB . GLU B 1 237 ? 26.612 13.519 31.915 1.00 28.34 ? 237 GLU B CB 1 ATOM 5894 C CG . GLU B 1 237 ? 27.362 12.189 31.663 1.00 34.10 ? 237 GLU B CG 1 ATOM 5895 C CD . GLU B 1 237 ? 28.322 12.127 30.419 1.00 40.20 ? 237 GLU B CD 1 ATOM 5896 O OE1 . GLU B 1 237 ? 28.355 13.033 29.532 1.00 39.34 ? 237 GLU B OE1 1 ATOM 5897 O OE2 . GLU B 1 237 ? 29.060 11.104 30.343 1.00 43.82 ? 237 GLU B OE2 1 ATOM 5898 N N . TRP B 1 238 ? 24.813 16.045 31.287 1.00 25.02 ? 238 TRP B N 1 ATOM 5899 C CA . TRP B 1 238 ? 24.074 17.232 31.708 1.00 24.31 ? 238 TRP B CA 1 ATOM 5900 C C . TRP B 1 238 ? 22.648 17.293 31.102 1.00 23.36 ? 238 TRP B C 1 ATOM 5901 O O . TRP B 1 238 ? 21.678 17.689 31.790 1.00 22.77 ? 238 TRP B O 1 ATOM 5902 C CB . TRP B 1 238 ? 24.879 18.496 31.361 1.00 24.82 ? 238 TRP B CB 1 ATOM 5903 C CG . TRP B 1 238 ? 24.290 19.769 31.896 1.00 24.61 ? 238 TRP B CG 1 ATOM 5904 C CD1 . TRP B 1 238 ? 24.654 20.423 33.049 1.00 25.44 ? 238 TRP B CD1 1 ATOM 5905 C CD2 . TRP B 1 238 ? 23.226 20.544 31.315 1.00 24.96 ? 238 TRP B CD2 1 ATOM 5906 N NE1 . TRP B 1 238 ? 23.879 21.548 33.215 1.00 24.38 ? 238 TRP B NE1 1 ATOM 5907 C CE2 . TRP B 1 238 ? 22.992 21.643 32.174 1.00 24.27 ? 238 TRP B CE2 1 ATOM 5908 C CE3 . TRP B 1 238 ? 22.428 20.399 30.164 1.00 25.79 ? 238 TRP B CE3 1 ATOM 5909 C CZ2 . TRP B 1 238 ? 21.999 22.609 31.912 1.00 25.46 ? 238 TRP B CZ2 1 ATOM 5910 C CZ3 . TRP B 1 238 ? 21.432 21.368 29.901 1.00 25.93 ? 238 TRP B CZ3 1 ATOM 5911 C CH2 . TRP B 1 238 ? 21.234 22.455 30.775 1.00 26.06 ? 238 TRP B CH2 1 ATOM 5912 N N . SER B 1 239 ? 22.502 16.910 29.834 1.00 21.40 ? 239 SER B N 1 ATOM 5913 C CA . SER B 1 239 ? 21.160 16.947 29.218 1.00 20.61 ? 239 SER B CA 1 ATOM 5914 C C . SER B 1 239 ? 20.254 15.870 29.787 1.00 20.01 ? 239 SER B C 1 ATOM 5915 O O . SER B 1 239 ? 19.058 16.125 30.004 1.00 19.37 ? 239 SER B O 1 ATOM 5916 C CB . SER B 1 239 ? 21.199 16.850 27.687 1.00 20.65 ? 239 SER B CB 1 ATOM 5917 O OG . SER B 1 239 ? 21.746 18.017 27.101 1.00 19.32 ? 239 SER B OG 1 ATOM 5918 N N . VAL B 1 240 ? 20.819 14.694 30.056 1.00 19.75 ? 240 VAL B N 1 ATOM 5919 C CA . VAL B 1 240 ? 20.051 13.591 30.674 1.00 21.28 ? 240 VAL B CA 1 ATOM 5920 C C . VAL B 1 240 ? 19.556 13.990 32.062 1.00 21.71 ? 240 VAL B C 1 ATOM 5921 O O . VAL B 1 240 ? 18.398 13.756 32.403 1.00 21.84 ? 240 VAL B O 1 ATOM 5922 C CB . VAL B 1 240 ? 20.833 12.270 30.735 1.00 21.21 ? 240 VAL B CB 1 ATOM 5923 C CG1 . VAL B 1 240 ? 20.062 11.216 31.548 1.00 21.15 ? 240 VAL B CG1 1 ATOM 5924 C CG2 . VAL B 1 240 ? 21.130 11.743 29.304 1.00 21.72 ? 240 VAL B CG2 1 ATOM 5925 N N . LYS B 1 241 ? 20.440 14.613 32.840 1.00 22.10 ? 241 LYS B N 1 ATOM 5926 C CA . LYS B 1 241 ? 20.105 15.076 34.183 1.00 22.94 ? 241 LYS B CA 1 ATOM 5927 C C . LYS B 1 241 ? 19.016 16.154 34.091 1.00 21.91 ? 241 LYS B C 1 ATOM 5928 O O . LYS B 1 241 ? 18.054 16.143 34.855 1.00 21.77 ? 241 LYS B O 1 ATOM 5929 C CB . LYS B 1 241 ? 21.368 15.612 34.868 1.00 23.22 ? 241 LYS B CB 1 ATOM 5930 C CG . LYS B 1 241 ? 21.212 15.936 36.358 1.00 27.42 ? 241 LYS B CG 1 ATOM 5931 C CD . LYS B 1 241 ? 22.552 16.423 36.935 1.00 32.94 ? 241 LYS B CD 1 ATOM 5932 C CE . LYS B 1 241 ? 23.036 17.718 36.239 1.00 36.28 ? 241 LYS B CE 1 ATOM 5933 N NZ . LYS B 1 241 ? 24.404 17.566 35.626 1.00 38.46 ? 241 LYS B NZ 1 ATOM 5934 N N . THR B 1 242 ? 19.150 17.045 33.115 1.00 21.85 ? 242 THR B N 1 ATOM 5935 C CA . THR B 1 242 ? 18.156 18.101 32.853 1.00 21.48 ? 242 THR B CA 1 ATOM 5936 C C . THR B 1 242 ? 16.776 17.540 32.446 1.00 21.70 ? 242 THR B C 1 ATOM 5937 O O . THR B 1 242 ? 15.748 18.041 32.930 1.00 22.15 ? 242 THR B O 1 ATOM 5938 C CB . THR B 1 242 ? 18.683 19.148 31.832 1.00 21.37 ? 242 THR B CB 1 ATOM 5939 O OG1 . THR B 1 242 ? 19.911 19.698 32.324 1.00 22.00 ? 242 THR B OG1 1 ATOM 5940 C CG2 . THR B 1 242 ? 17.685 20.300 31.610 1.00 20.63 ? 242 THR B CG2 1 ATOM 5941 N N . TYR B 1 243 ? 16.741 16.503 31.592 1.00 21.57 ? 243 TYR B N 1 ATOM 5942 C CA . TYR B 1 243 ? 15.463 15.852 31.226 1.00 21.70 ? 243 TYR B CA 1 ATOM 5943 C C . TYR B 1 243 ? 14.775 15.251 32.462 1.00 21.89 ? 243 TYR B C 1 ATOM 5944 O O . TYR B 1 243 ? 13.550 15.371 32.625 1.00 21.21 ? 243 TYR B O 1 ATOM 5945 C CB . TYR B 1 243 ? 15.673 14.734 30.197 1.00 22.01 ? 243 TYR B CB 1 ATOM 5946 C CG . TYR B 1 243 ? 15.682 15.152 28.727 1.00 22.13 ? 243 TYR B CG 1 ATOM 5947 C CD1 . TYR B 1 243 ? 14.523 15.625 28.096 1.00 21.81 ? 243 TYR B CD1 1 ATOM 5948 C CD2 . TYR B 1 243 ? 16.838 15.008 27.955 1.00 22.71 ? 243 TYR B CD2 1 ATOM 5949 C CE1 . TYR B 1 243 ? 14.535 15.984 26.734 1.00 22.78 ? 243 TYR B CE1 1 ATOM 5950 C CE2 . TYR B 1 243 ? 16.863 15.354 26.602 1.00 21.97 ? 243 TYR B CE2 1 ATOM 5951 C CZ . TYR B 1 243 ? 15.724 15.837 26.007 1.00 21.93 ? 243 TYR B CZ 1 ATOM 5952 O OH . TYR B 1 243 ? 15.785 16.171 24.704 1.00 22.50 ? 243 TYR B OH 1 ATOM 5953 N N . GLN B 1 244 ? 15.570 14.584 33.307 1.00 21.47 ? 244 GLN B N 1 ATOM 5954 C CA . GLN B 1 244 ? 15.072 13.946 34.535 1.00 21.69 ? 244 GLN B CA 1 ATOM 5955 C C . GLN B 1 244 ? 14.485 14.999 35.500 1.00 21.76 ? 244 GLN B C 1 ATOM 5956 O O . GLN B 1 244 ? 13.398 14.795 36.040 1.00 20.74 ? 244 GLN B O 1 ATOM 5957 C CB . GLN B 1 244 ? 16.187 13.141 35.220 1.00 21.26 ? 244 GLN B CB 1 ATOM 5958 C CG . GLN B 1 244 ? 15.762 12.323 36.453 1.00 23.22 ? 244 GLN B CG 1 ATOM 5959 C CD . GLN B 1 244 ? 16.932 11.564 37.110 1.00 29.11 ? 244 GLN B CD 1 ATOM 5960 O OE1 . GLN B 1 244 ? 18.096 11.992 37.060 1.00 31.68 ? 244 GLN B OE1 1 ATOM 5961 N NE2 . GLN B 1 244 ? 16.624 10.428 37.716 1.00 31.20 ? 244 GLN B NE2 1 ATOM 5962 N N . GLU B 1 245 ? 15.209 16.119 35.665 1.00 22.03 ? 245 GLU B N 1 ATOM 5963 C CA . GLU B 1 245 ? 14.834 17.225 36.563 1.00 22.37 ? 245 GLU B CA 1 ATOM 5964 C C . GLU B 1 245 ? 13.576 17.977 36.113 1.00 21.95 ? 245 GLU B C 1 ATOM 5965 O O . GLU B 1 245 ? 12.687 18.257 36.934 1.00 20.38 ? 245 GLU B O 1 ATOM 5966 C CB . GLU B 1 245 ? 15.996 18.204 36.739 1.00 22.52 ? 245 GLU B CB 1 ATOM 5967 C CG . GLU B 1 245 ? 17.086 17.647 37.608 1.00 25.81 ? 245 GLU B CG 1 ATOM 5968 C CD . GLU B 1 245 ? 18.308 18.552 37.774 1.00 31.06 ? 245 GLU B CD 1 ATOM 5969 O OE1 . GLU B 1 245 ? 18.488 19.528 37.011 1.00 34.77 ? 245 GLU B OE1 1 ATOM 5970 O OE2 . GLU B 1 245 ? 19.108 18.262 38.682 1.00 34.10 ? 245 GLU B OE2 1 ATOM 5971 N N . VAL B 1 246 ? 13.507 18.283 34.811 1.00 20.57 ? 246 VAL B N 1 ATOM 5972 C CA . VAL B 1 246 ? 12.338 18.922 34.226 1.00 19.80 ? 246 VAL B CA 1 ATOM 5973 C C . VAL B 1 246 ? 11.110 17.977 34.288 1.00 19.92 ? 246 VAL B C 1 ATOM 5974 O O . VAL B 1 246 ? 10.032 18.403 34.715 1.00 18.90 ? 246 VAL B O 1 ATOM 5975 C CB . VAL B 1 246 ? 12.632 19.483 32.799 1.00 20.40 ? 246 VAL B CB 1 ATOM 5976 C CG1 . VAL B 1 246 ? 11.420 20.105 32.209 1.00 17.10 ? 246 VAL B CG1 1 ATOM 5977 C CG2 . VAL B 1 246 ? 13.759 20.571 32.857 1.00 19.91 ? 246 VAL B CG2 1 ATOM 5978 N N . ALA B 1 247 ? 11.284 16.695 33.936 1.00 19.09 ? 247 ALA B N 1 ATOM 5979 C CA . ALA B 1 247 ? 10.205 15.701 34.105 1.00 19.89 ? 247 ALA B CA 1 ATOM 5980 C C . ALA B 1 247 ? 9.727 15.600 35.568 1.00 20.41 ? 247 ALA B C 1 ATOM 5981 O O . ALA B 1 247 ? 8.534 15.478 35.827 1.00 19.50 ? 247 ALA B O 1 ATOM 5982 C CB . ALA B 1 247 ? 10.631 14.303 33.585 1.00 19.65 ? 247 ALA B CB 1 ATOM 5983 N N . GLN B 1 248 ? 10.663 15.655 36.504 1.00 20.91 ? 248 GLN B N 1 ATOM 5984 C CA . GLN B 1 248 ? 10.312 15.574 37.920 1.00 23.18 ? 248 GLN B CA 1 ATOM 5985 C C . GLN B 1 248 ? 9.490 16.770 38.339 1.00 22.83 ? 248 GLN B C 1 ATOM 5986 O O . GLN B 1 248 ? 8.484 16.612 39.036 1.00 23.85 ? 248 GLN B O 1 ATOM 5987 C CB . GLN B 1 248 ? 11.558 15.394 38.785 1.00 23.39 ? 248 GLN B CB 1 ATOM 5988 C CG . GLN B 1 248 ? 11.866 13.913 39.003 1.00 28.88 ? 248 GLN B CG 1 ATOM 5989 C CD . GLN B 1 248 ? 13.342 13.612 39.268 1.00 34.16 ? 248 GLN B CD 1 ATOM 5990 O OE1 . GLN B 1 248 ? 14.121 14.484 39.674 1.00 35.85 ? 248 GLN B OE1 1 ATOM 5991 N NE2 . GLN B 1 248 ? 13.725 12.353 39.049 1.00 38.32 ? 248 GLN B NE2 1 ATOM 5992 N N . LYS B 1 249 ? 9.900 17.946 37.869 1.00 23.45 ? 249 LYS B N 1 ATOM 5993 C CA . LYS B 1 249 ? 9.164 19.198 38.037 1.00 24.38 ? 249 LYS B CA 1 ATOM 5994 C C . LYS B 1 249 ? 7.725 19.111 37.483 1.00 24.60 ? 249 LYS B C 1 ATOM 5995 O O . LYS B 1 249 ? 6.761 19.473 38.170 1.00 23.47 ? 249 LYS B O 1 ATOM 5996 C CB . LYS B 1 249 ? 9.930 20.328 37.345 1.00 25.11 ? 249 LYS B CB 1 ATOM 5997 C CG . LYS B 1 249 ? 9.491 21.727 37.706 1.00 30.22 ? 249 LYS B CG 1 ATOM 5998 C CD . LYS B 1 249 ? 10.098 22.174 39.044 1.00 37.22 ? 249 LYS B CD 1 ATOM 5999 C CE . LYS B 1 249 ? 11.439 22.892 38.862 1.00 40.57 ? 249 LYS B CE 1 ATOM 6000 N NZ . LYS B 1 249 ? 11.248 24.348 38.527 1.00 43.34 ? 249 LYS B NZ 1 ATOM 6001 N N . PHE B 1 250 ? 7.592 18.632 36.245 1.00 23.30 ? 250 PHE B N 1 ATOM 6002 C CA . PHE B 1 250 ? 6.282 18.425 35.641 1.00 23.17 ? 250 PHE B CA 1 ATOM 6003 C C . PHE B 1 250 ? 5.369 17.481 36.452 1.00 23.45 ? 250 PHE B C 1 ATOM 6004 O O . PHE B 1 250 ? 4.210 17.809 36.709 1.00 23.56 ? 250 PHE B O 1 ATOM 6005 C CB . PHE B 1 250 ? 6.415 17.958 34.169 1.00 22.63 ? 250 PHE B CB 1 ATOM 6006 C CG . PHE B 1 250 ? 5.129 18.068 33.397 1.00 20.80 ? 250 PHE B CG 1 ATOM 6007 C CD1 . PHE B 1 250 ? 4.786 19.255 32.770 1.00 20.80 ? 250 PHE B CD1 1 ATOM 6008 C CD2 . PHE B 1 250 ? 4.252 16.982 33.324 1.00 19.13 ? 250 PHE B CD2 1 ATOM 6009 C CE1 . PHE B 1 250 ? 3.574 19.373 32.075 1.00 20.07 ? 250 PHE B CE1 1 ATOM 6010 C CE2 . PHE B 1 250 ? 3.044 17.071 32.634 1.00 18.88 ? 250 PHE B CE2 1 ATOM 6011 C CZ . PHE B 1 250 ? 2.690 18.282 32.012 1.00 20.10 ? 250 PHE B CZ 1 ATOM 6012 N N . VAL B 1 251 ? 5.897 16.326 36.860 1.00 24.02 ? 251 VAL B N 1 ATOM 6013 C CA . VAL B 1 251 ? 5.129 15.344 37.639 1.00 24.89 ? 251 VAL B CA 1 ATOM 6014 C C . VAL B 1 251 ? 4.638 15.941 38.993 1.00 25.88 ? 251 VAL B C 1 ATOM 6015 O O . VAL B 1 251 ? 3.497 15.690 39.426 1.00 25.65 ? 251 VAL B O 1 ATOM 6016 C CB . VAL B 1 251 ? 5.919 14.003 37.773 1.00 25.05 ? 251 VAL B CB 1 ATOM 6017 C CG1 . VAL B 1 251 ? 5.374 13.117 38.871 1.00 24.10 ? 251 VAL B CG1 1 ATOM 6018 C CG2 . VAL B 1 251 ? 5.939 13.236 36.409 1.00 25.36 ? 251 VAL B CG2 1 ATOM 6019 N N . GLU B 1 252 ? 5.473 16.780 39.606 1.00 26.61 ? 252 GLU B N 1 ATOM 6020 C CA . GLU B 1 252 ? 5.100 17.505 40.821 1.00 27.97 ? 252 GLU B CA 1 ATOM 6021 C C . GLU B 1 252 ? 3.779 18.249 40.736 1.00 27.87 ? 252 GLU B C 1 ATOM 6022 O O . GLU B 1 252 ? 3.046 18.267 41.700 1.00 28.68 ? 252 GLU B O 1 ATOM 6023 C CB . GLU B 1 252 ? 6.191 18.501 41.214 1.00 28.40 ? 252 GLU B CB 1 ATOM 6024 C CG . GLU B 1 252 ? 7.245 17.933 42.079 1.00 30.91 ? 252 GLU B CG 1 ATOM 6025 C CD . GLU B 1 252 ? 8.404 18.910 42.301 1.00 36.88 ? 252 GLU B CD 1 ATOM 6026 O OE1 . GLU B 1 252 ? 8.167 20.132 42.439 1.00 38.24 ? 252 GLU B OE1 1 ATOM 6027 O OE2 . GLU B 1 252 ? 9.570 18.452 42.318 1.00 40.88 ? 252 GLU B OE2 1 ATOM 6028 N N . THR B 1 253 ? 3.473 18.873 39.601 1.00 27.94 ? 253 THR B N 1 ATOM 6029 C CA . THR B 1 253 ? 2.199 19.574 39.462 1.00 28.12 ? 253 THR B CA 1 ATOM 6030 C C . THR B 1 253 ? 1.192 18.867 38.550 1.00 27.26 ? 253 THR B C 1 ATOM 6031 O O . THR B 1 253 ? 0.106 19.390 38.308 1.00 27.35 ? 253 THR B O 1 ATOM 6032 C CB . THR B 1 253 ? 2.381 21.022 38.963 1.00 28.09 ? 253 THR B CB 1 ATOM 6033 O OG1 . THR B 1 253 ? 3.102 21.001 37.731 1.00 30.95 ? 253 THR B OG1 1 ATOM 6034 C CG2 . THR B 1 253 ? 3.133 21.872 40.002 1.00 28.59 ? 253 THR B CG2 1 ATOM 6035 N N . HIS B 1 254 ? 1.562 17.695 38.039 1.00 26.40 ? 254 HIS B N 1 ATOM 6036 C CA . HIS B 1 254 ? 0.680 16.897 37.198 1.00 25.75 ? 254 HIS B CA 1 ATOM 6037 C C . HIS B 1 254 ? 0.810 15.458 37.678 1.00 26.08 ? 254 HIS B C 1 ATOM 6038 O O . HIS B 1 254 ? 1.448 14.636 37.000 1.00 25.18 ? 254 HIS B O 1 ATOM 6039 C CB . HIS B 1 254 ? 1.060 17.007 35.708 1.00 25.40 ? 254 HIS B CB 1 ATOM 6040 C CG . HIS B 1 254 ? 1.118 18.415 35.193 1.00 24.62 ? 254 HIS B CG 1 ATOM 6041 N ND1 . HIS B 1 254 ? 2.201 19.238 35.407 1.00 24.04 ? 254 HIS B ND1 1 ATOM 6042 C CD2 . HIS B 1 254 ? 0.234 19.141 34.467 1.00 23.27 ? 254 HIS B CD2 1 ATOM 6043 C CE1 . HIS B 1 254 ? 1.984 20.413 34.836 1.00 24.19 ? 254 HIS B CE1 1 ATOM 6044 N NE2 . HIS B 1 254 ? 0.796 20.382 34.263 1.00 24.77 ? 254 HIS B NE2 1 ATOM 6045 N N . PRO B 1 255 ? 0.204 15.140 38.850 1.00 26.25 ? 255 PRO B N 1 ATOM 6046 C CA . PRO B 1 255 ? 0.541 13.882 39.527 1.00 26.32 ? 255 PRO B CA 1 ATOM 6047 C C . PRO B 1 255 ? 0.099 12.608 38.797 1.00 26.36 ? 255 PRO B C 1 ATOM 6048 O O . PRO B 1 255 ? 0.638 11.532 39.086 1.00 27.11 ? 255 PRO B O 1 ATOM 6049 C CB . PRO B 1 255 ? -0.122 14.018 40.922 1.00 26.67 ? 255 PRO B CB 1 ATOM 6050 C CG . PRO B 1 255 ? -1.160 15.065 40.767 1.00 26.47 ? 255 PRO B CG 1 ATOM 6051 C CD . PRO B 1 255 ? -0.684 15.992 39.672 1.00 26.51 ? 255 PRO B CD 1 ATOM 6052 N N . GLU B 1 256 ? -0.838 12.714 37.855 1.00 25.68 ? 256 GLU B N 1 ATOM 6053 C CA . GLU B 1 256 ? -1.181 11.552 37.009 1.00 25.89 ? 256 GLU B CA 1 ATOM 6054 C C . GLU B 1 256 ? -0.180 11.259 35.858 1.00 25.13 ? 256 GLU B C 1 ATOM 6055 O O . GLU B 1 256 ? -0.179 10.149 35.297 1.00 25.37 ? 256 GLU B O 1 ATOM 6056 C CB . GLU B 1 256 ? -2.608 11.694 36.452 1.00 25.58 ? 256 GLU B CB 1 ATOM 6057 C CG . GLU B 1 256 ? -3.702 11.696 37.511 1.00 27.52 ? 256 GLU B CG 1 ATOM 6058 C CD . GLU B 1 256 ? -5.063 11.890 36.866 1.00 30.03 ? 256 GLU B CD 1 ATOM 6059 O OE1 . GLU B 1 256 ? -5.626 10.890 36.354 1.00 31.13 ? 256 GLU B OE1 1 ATOM 6060 O OE2 . GLU B 1 256 ? -5.550 13.050 36.836 1.00 31.94 ? 256 GLU B OE2 1 ATOM 6061 N N . PHE B 1 257 ? 0.652 12.243 35.519 1.00 23.68 ? 257 PHE B N 1 ATOM 6062 C CA . PHE B 1 257 ? 1.716 12.069 34.527 1.00 23.26 ? 257 PHE B CA 1 ATOM 6063 C C . PHE B 1 257 ? 2.800 11.102 35.052 1.00 23.52 ? 257 PHE B C 1 ATOM 6064 O O . PHE B 1 257 ? 3.265 11.249 36.179 1.00 23.41 ? 257 PHE B O 1 ATOM 6065 C CB . PHE B 1 257 ? 2.337 13.424 34.136 1.00 22.93 ? 257 PHE B CB 1 ATOM 6066 C CG . PHE B 1 257 ? 3.110 13.384 32.817 1.00 22.91 ? 257 PHE B CG 1 ATOM 6067 C CD1 . PHE B 1 257 ? 2.428 13.389 31.594 1.00 21.11 ? 257 PHE B CD1 1 ATOM 6068 C CD2 . PHE B 1 257 ? 4.508 13.330 32.809 1.00 19.80 ? 257 PHE B CD2 1 ATOM 6069 C CE1 . PHE B 1 257 ? 3.133 13.331 30.378 1.00 21.51 ? 257 PHE B CE1 1 ATOM 6070 C CE2 . PHE B 1 257 ? 5.229 13.277 31.582 1.00 19.68 ? 257 PHE B CE2 1 ATOM 6071 C CZ . PHE B 1 257 ? 4.544 13.261 30.384 1.00 19.04 ? 257 PHE B CZ 1 ATOM 6072 N N . ILE B 1 258 ? 3.182 10.121 34.230 1.00 22.65 ? 258 ILE B N 1 ATOM 6073 C CA . ILE B 1 258 ? 4.169 9.110 34.617 1.00 22.50 ? 258 ILE B CA 1 ATOM 6074 C C . ILE B 1 258 ? 5.602 9.679 34.487 1.00 22.57 ? 258 ILE B C 1 ATOM 6075 O O . ILE B 1 258 ? 6.407 9.526 35.399 1.00 22.79 ? 258 ILE B O 1 ATOM 6076 C CB . ILE B 1 258 ? 4.000 7.774 33.808 1.00 22.38 ? 258 ILE B CB 1 ATOM 6077 C CG1 . ILE B 1 258 ? 2.543 7.281 33.853 1.00 23.38 ? 258 ILE B CG1 1 ATOM 6078 C CG2 . ILE B 1 258 ? 4.961 6.690 34.290 1.00 22.49 ? 258 ILE B CG2 1 ATOM 6079 C CD1 . ILE B 1 258 ? 2.053 6.815 35.241 1.00 23.23 ? 258 ILE B CD1 1 ATOM 6080 N N . GLY B 1 259 ? 5.909 10.361 33.387 1.00 21.86 ? 259 GLY B N 1 ATOM 6081 C CA . GLY B 1 259 ? 7.234 10.944 33.234 1.00 22.26 ? 259 GLY B CA 1 ATOM 6082 C C . GLY B 1 259 ? 7.827 10.659 31.865 1.00 22.16 ? 259 GLY B C 1 ATOM 6083 O O . GLY B 1 259 ? 7.095 10.421 30.893 1.00 22.73 ? 259 GLY B O 1 ATOM 6084 N N . ILE B 1 260 ? 9.146 10.713 31.764 1.00 21.61 ? 260 ILE B N 1 ATOM 6085 C CA . ILE B 1 260 ? 9.768 10.475 30.464 1.00 21.77 ? 260 ILE B CA 1 ATOM 6086 C C . ILE B 1 260 ? 11.004 9.593 30.586 1.00 21.03 ? 260 ILE B C 1 ATOM 6087 O O . ILE B 1 260 ? 11.655 9.571 31.628 1.00 21.21 ? 260 ILE B O 1 ATOM 6088 C CB . ILE B 1 260 ? 10.166 11.795 29.738 1.00 21.90 ? 260 ILE B CB 1 ATOM 6089 C CG1 . ILE B 1 260 ? 11.321 12.491 30.432 1.00 22.70 ? 260 ILE B CG1 1 ATOM 6090 C CG2 . ILE B 1 260 ? 8.951 12.753 29.546 1.00 22.73 ? 260 ILE B CG2 1 ATOM 6091 C CD1 . ILE B 1 260 ? 11.719 13.817 29.747 1.00 25.75 ? 260 ILE B CD1 1 ATOM 6092 N N . LYS B 1 261 ? 11.330 8.893 29.511 1.00 19.34 ? 261 LYS B N 1 ATOM 6093 C CA . LYS B 1 261 ? 12.639 8.290 29.375 1.00 19.39 ? 261 LYS B CA 1 ATOM 6094 C C . LYS B 1 261 ? 13.285 8.677 28.034 1.00 19.51 ? 261 LYS B C 1 ATOM 6095 O O . LYS B 1 261 ? 12.599 9.130 27.092 1.00 17.84 ? 261 LYS B O 1 ATOM 6096 C CB . LYS B 1 261 ? 12.565 6.762 29.570 1.00 19.65 ? 261 LYS B CB 1 ATOM 6097 C CG . LYS B 1 261 ? 12.118 6.346 31.000 1.00 21.65 ? 261 LYS B CG 1 ATOM 6098 C CD . LYS B 1 261 ? 12.541 4.918 31.295 1.00 24.93 ? 261 LYS B CD 1 ATOM 6099 C CE . LYS B 1 261 ? 11.741 4.314 32.449 1.00 28.65 ? 261 LYS B CE 1 ATOM 6100 N NZ . LYS B 1 261 ? 12.003 4.933 33.800 1.00 31.53 ? 261 LYS B NZ 1 ATOM 6101 N N . ILE B 1 262 ? 14.605 8.488 27.966 1.00 19.18 ? 262 ILE B N 1 ATOM 6102 C CA . ILE B 1 262 ? 15.422 8.928 26.856 1.00 19.15 ? 262 ILE B CA 1 ATOM 6103 C C . ILE B 1 262 ? 16.030 7.695 26.179 1.00 18.80 ? 262 ILE B C 1 ATOM 6104 O O . ILE B 1 262 ? 16.560 6.777 26.843 1.00 17.96 ? 262 ILE B O 1 ATOM 6105 C CB . ILE B 1 262 ? 16.553 9.919 27.341 1.00 20.16 ? 262 ILE B CB 1 ATOM 6106 C CG1 . ILE B 1 262 ? 15.957 11.157 28.008 1.00 21.46 ? 262 ILE B CG1 1 ATOM 6107 C CG2 . ILE B 1 262 ? 17.423 10.427 26.181 1.00 20.10 ? 262 ILE B CG2 1 ATOM 6108 C CD1 . ILE B 1 262 ? 14.964 11.938 27.133 1.00 22.46 ? 262 ILE B CD1 1 ATOM 6109 N N . ILE B 1 263 ? 15.906 7.664 24.863 1.00 17.86 ? 263 ILE B N 1 ATOM 6110 C CA . ILE B 1 263 ? 16.637 6.717 24.045 1.00 17.54 ? 263 ILE B CA 1 ATOM 6111 C C . ILE B 1 263 ? 17.716 7.550 23.367 1.00 17.61 ? 263 ILE B C 1 ATOM 6112 O O . ILE B 1 263 ? 17.422 8.403 22.524 1.00 15.95 ? 263 ILE B O 1 ATOM 6113 C CB . ILE B 1 263 ? 15.725 6.014 23.014 1.00 17.76 ? 263 ILE B CB 1 ATOM 6114 C CG1 . ILE B 1 263 ? 14.688 5.124 23.744 1.00 16.98 ? 263 ILE B CG1 1 ATOM 6115 C CG2 . ILE B 1 263 ? 16.581 5.167 21.987 1.00 15.79 ? 263 ILE B CG2 1 ATOM 6116 C CD1 . ILE B 1 263 ? 13.455 4.755 22.879 1.00 17.80 ? 263 ILE B CD1 1 ATOM 6117 N N . TYR B 1 264 ? 18.970 7.340 23.762 1.00 18.02 ? 264 TYR B N 1 ATOM 6118 C CA . TYR B 1 264 ? 20.063 8.100 23.144 1.00 18.65 ? 264 TYR B CA 1 ATOM 6119 C C . TYR B 1 264 ? 20.188 7.685 21.666 1.00 18.40 ? 264 TYR B C 1 ATOM 6120 O O . TYR B 1 264 ? 20.187 6.512 21.361 1.00 18.14 ? 264 TYR B O 1 ATOM 6121 C CB . TYR B 1 264 ? 21.379 7.876 23.910 1.00 18.71 ? 264 TYR B CB 1 ATOM 6122 C CG . TYR B 1 264 ? 22.612 8.516 23.305 1.00 19.59 ? 264 TYR B CG 1 ATOM 6123 C CD1 . TYR B 1 264 ? 22.611 9.848 22.875 1.00 21.02 ? 264 TYR B CD1 1 ATOM 6124 C CD2 . TYR B 1 264 ? 23.800 7.799 23.208 1.00 20.29 ? 264 TYR B CD2 1 ATOM 6125 C CE1 . TYR B 1 264 ? 23.782 10.444 22.336 1.00 21.01 ? 264 TYR B CE1 1 ATOM 6126 C CE2 . TYR B 1 264 ? 24.959 8.372 22.690 1.00 22.25 ? 264 TYR B CE2 1 ATOM 6127 C CZ . TYR B 1 264 ? 24.936 9.681 22.247 1.00 24.17 ? 264 TYR B CZ 1 ATOM 6128 O OH . TYR B 1 264 ? 26.093 10.215 21.754 1.00 26.21 ? 264 TYR B OH 1 ATOM 6129 N N . SER B 1 265 ? 20.265 8.655 20.757 1.00 19.13 ? 265 SER B N 1 ATOM 6130 C CA . SER B 1 265 ? 20.328 8.336 19.323 1.00 20.18 ? 265 SER B CA 1 ATOM 6131 C C . SER B 1 265 ? 21.498 9.048 18.640 1.00 20.10 ? 265 SER B C 1 ATOM 6132 O O . SER B 1 265 ? 21.963 10.073 19.125 1.00 20.17 ? 265 SER B O 1 ATOM 6133 C CB . SER B 1 265 ? 19.021 8.735 18.642 1.00 20.81 ? 265 SER B CB 1 ATOM 6134 O OG . SER B 1 265 ? 18.900 10.160 18.639 1.00 23.63 ? 265 SER B OG 1 ATOM 6135 N N . ASP B 1 266 ? 22.000 8.475 17.544 1.00 20.39 ? 266 ASP B N 1 ATOM 6136 C CA . ASP B 1 266 ? 22.988 9.166 16.699 1.00 20.58 ? 266 ASP B CA 1 ATOM 6137 C C . ASP B 1 266 ? 22.675 8.946 15.199 1.00 20.65 ? 266 ASP B C 1 ATOM 6138 O O . ASP B 1 266 ? 21.911 8.064 14.833 1.00 20.31 ? 266 ASP B O 1 ATOM 6139 C CB . ASP B 1 266 ? 24.425 8.735 17.070 1.00 20.64 ? 266 ASP B CB 1 ATOM 6140 C CG . ASP B 1 266 ? 25.501 9.806 16.734 1.00 22.06 ? 266 ASP B CG 1 ATOM 6141 O OD1 . ASP B 1 266 ? 25.199 10.845 16.110 1.00 22.43 ? 266 ASP B OD1 1 ATOM 6142 O OD2 . ASP B 1 266 ? 26.688 9.592 17.105 1.00 26.80 ? 266 ASP B OD2 1 ATOM 6143 N N . HIS B 1 267 ? 23.264 9.766 14.347 1.00 21.01 ? 267 HIS B N 1 ATOM 6144 C CA . HIS B 1 267 ? 22.818 9.885 12.966 1.00 21.42 ? 267 HIS B CA 1 ATOM 6145 C C . HIS B 1 267 ? 23.509 8.807 12.120 1.00 22.49 ? 267 HIS B C 1 ATOM 6146 O O . HIS B 1 267 ? 24.736 8.624 12.200 1.00 22.02 ? 267 HIS B O 1 ATOM 6147 C CB . HIS B 1 267 ? 23.091 11.315 12.454 1.00 20.45 ? 267 HIS B CB 1 ATOM 6148 C CG . HIS B 1 267 ? 22.361 11.662 11.193 1.00 22.62 ? 267 HIS B CG 1 ATOM 6149 N ND1 . HIS B 1 267 ? 22.832 11.326 9.940 1.00 25.70 ? 267 HIS B ND1 1 ATOM 6150 C CD2 . HIS B 1 267 ? 21.179 12.293 10.988 1.00 25.32 ? 267 HIS B CD2 1 ATOM 6151 C CE1 . HIS B 1 267 ? 21.979 11.737 9.020 1.00 25.02 ? 267 HIS B CE1 1 ATOM 6152 N NE2 . HIS B 1 267 ? 20.968 12.331 9.628 1.00 27.60 ? 267 HIS B NE2 1 ATOM 6153 N N . ARG B 1 268 ? 22.721 8.109 11.301 1.00 22.68 ? 268 ARG B N 1 ATOM 6154 C CA . ARG B 1 268 ? 23.213 6.988 10.499 1.00 23.48 ? 268 ARG B CA 1 ATOM 6155 C C . ARG B 1 268 ? 24.047 7.351 9.254 1.00 24.08 ? 268 ARG B C 1 ATOM 6156 O O . ARG B 1 268 ? 24.344 6.478 8.429 1.00 24.05 ? 268 ARG B O 1 ATOM 6157 C CB . ARG B 1 268 ? 22.047 6.066 10.101 1.00 23.53 ? 268 ARG B CB 1 ATOM 6158 C CG . ARG B 1 268 ? 21.035 6.704 9.173 1.00 23.20 ? 268 ARG B CG 1 ATOM 6159 C CD . ARG B 1 268 ? 19.720 5.917 9.088 1.00 21.52 ? 268 ARG B CD 1 ATOM 6160 N NE . ARG B 1 268 ? 19.995 4.502 8.916 1.00 21.29 ? 268 ARG B NE 1 ATOM 6161 C CZ . ARG B 1 268 ? 19.532 3.541 9.701 1.00 21.99 ? 268 ARG B CZ 1 ATOM 6162 N NH1 . ARG B 1 268 ? 18.690 3.819 10.713 1.00 20.32 ? 268 ARG B NH1 1 ATOM 6163 N NH2 . ARG B 1 268 ? 19.894 2.297 9.439 1.00 20.49 ? 268 ARG B NH2 1 ATOM 6164 N N . SER B 1 269 ? 24.408 8.620 9.100 1.00 25.52 ? 269 SER B N 1 ATOM 6165 C CA . SER B 1 269 ? 25.369 9.018 8.054 1.00 26.41 ? 269 SER B CA 1 ATOM 6166 C C . SER B 1 269 ? 26.824 8.890 8.552 1.00 27.42 ? 269 SER B C 1 ATOM 6167 O O . SER B 1 269 ? 27.771 8.922 7.758 1.00 27.69 ? 269 SER B O 1 ATOM 6168 C CB . SER B 1 269 ? 25.108 10.455 7.620 1.00 26.34 ? 269 SER B CB 1 ATOM 6169 O OG . SER B 1 269 ? 25.234 11.329 8.738 1.00 27.49 ? 269 SER B OG 1 ATOM 6170 N N . LYS B 1 270 ? 26.988 8.727 9.866 1.00 27.99 ? 270 LYS B N 1 ATOM 6171 C CA . LYS B 1 270 ? 28.306 8.752 10.517 1.00 27.67 ? 270 LYS B CA 1 ATOM 6172 C C . LYS B 1 270 ? 29.142 7.471 10.326 1.00 28.08 ? 270 LYS B C 1 ATOM 6173 O O . LYS B 1 270 ? 28.607 6.368 10.142 1.00 26.53 ? 270 LYS B O 1 ATOM 6174 C CB . LYS B 1 270 ? 28.139 9.098 12.011 1.00 27.97 ? 270 LYS B CB 1 ATOM 6175 C CG . LYS B 1 270 ? 27.782 10.578 12.324 1.00 27.74 ? 270 LYS B CG 1 ATOM 6176 C CD . LYS B 1 270 ? 27.715 10.762 13.856 1.00 30.77 ? 270 LYS B CD 1 ATOM 6177 C CE . LYS B 1 270 ? 27.430 12.195 14.318 1.00 33.11 ? 270 LYS B CE 1 ATOM 6178 N NZ . LYS B 1 270 ? 26.303 12.774 13.552 1.00 37.38 ? 270 LYS B NZ 1 ATOM 6179 N N . ASP B 1 271 ? 30.472 7.617 10.373 1.00 28.54 ? 271 ASP B N 1 ATOM 6180 C CA . ASP B 1 271 ? 31.369 6.484 10.186 1.00 29.56 ? 271 ASP B CA 1 ATOM 6181 C C . ASP B 1 271 ? 31.219 5.511 11.340 1.00 28.88 ? 271 ASP B C 1 ATOM 6182 O O . ASP B 1 271 ? 30.862 5.917 12.447 1.00 29.57 ? 271 ASP B O 1 ATOM 6183 C CB . ASP B 1 271 ? 32.843 6.951 10.077 1.00 31.46 ? 271 ASP B CB 1 ATOM 6184 C CG . ASP B 1 271 ? 33.133 7.706 8.785 1.00 33.87 ? 271 ASP B CG 1 ATOM 6185 O OD1 . ASP B 1 271 ? 32.798 7.189 7.693 1.00 39.26 ? 271 ASP B OD1 1 ATOM 6186 O OD2 . ASP B 1 271 ? 33.721 8.813 8.857 1.00 38.15 ? 271 ASP B OD2 1 ATOM 6187 N N . VAL B 1 272 ? 31.499 4.240 11.087 1.00 28.37 ? 272 VAL B N 1 ATOM 6188 C CA . VAL B 1 272 ? 31.373 3.184 12.092 1.00 28.64 ? 272 VAL B CA 1 ATOM 6189 C C . VAL B 1 272 ? 32.169 3.450 13.391 1.00 29.36 ? 272 VAL B C 1 ATOM 6190 O O . VAL B 1 272 ? 31.651 3.215 14.495 1.00 28.88 ? 272 VAL B O 1 ATOM 6191 C CB . VAL B 1 272 ? 31.661 1.761 11.493 1.00 28.92 ? 272 VAL B CB 1 ATOM 6192 C CG1 . VAL B 1 272 ? 33.019 1.691 10.819 1.00 29.76 ? 272 VAL B CG1 1 ATOM 6193 C CG2 . VAL B 1 272 ? 31.531 0.663 12.555 1.00 28.45 ? 272 VAL B CG2 1 ATOM 6194 N N . ALA B 1 273 ? 33.401 3.961 13.265 1.00 28.74 ? 273 ALA B N 1 ATOM 6195 C CA . ALA B 1 273 ? 34.199 4.307 14.452 1.00 29.11 ? 273 ALA B CA 1 ATOM 6196 C C . ALA B 1 273 ? 33.551 5.401 15.309 1.00 28.44 ? 273 ALA B C 1 ATOM 6197 O O . ALA B 1 273 ? 33.640 5.367 16.542 1.00 29.00 ? 273 ALA B O 1 ATOM 6198 C CB . ALA B 1 273 ? 35.625 4.730 14.049 1.00 29.40 ? 273 ALA B CB 1 ATOM 6199 N N . VAL B 1 274 ? 32.911 6.372 14.659 1.00 27.91 ? 274 VAL B N 1 ATOM 6200 C CA . VAL B 1 274 ? 32.236 7.451 15.371 1.00 26.98 ? 274 VAL B CA 1 ATOM 6201 C C . VAL B 1 274 ? 31.044 6.877 16.148 1.00 26.68 ? 274 VAL B C 1 ATOM 6202 O O . VAL B 1 274 ? 30.812 7.254 17.297 1.00 26.68 ? 274 VAL B O 1 ATOM 6203 C CB . VAL B 1 274 ? 31.771 8.585 14.423 1.00 26.56 ? 274 VAL B CB 1 ATOM 6204 C CG1 . VAL B 1 274 ? 30.960 9.610 15.172 1.00 26.99 ? 274 VAL B CG1 1 ATOM 6205 C CG2 . VAL B 1 274 ? 32.955 9.260 13.723 1.00 27.18 ? 274 VAL B CG2 1 ATOM 6206 N N . ILE B 1 275 ? 30.293 5.979 15.511 1.00 25.99 ? 275 ILE B N 1 ATOM 6207 C CA . ILE B 1 275 ? 29.177 5.278 16.160 1.00 25.34 ? 275 ILE B CA 1 ATOM 6208 C C . ILE B 1 275 ? 29.642 4.368 17.314 1.00 25.29 ? 275 ILE B C 1 ATOM 6209 O O . ILE B 1 275 ? 28.930 4.221 18.319 1.00 24.34 ? 275 ILE B O 1 ATOM 6210 C CB . ILE B 1 275 ? 28.303 4.488 15.124 1.00 24.71 ? 275 ILE B CB 1 ATOM 6211 C CG1 . ILE B 1 275 ? 27.672 5.438 14.093 1.00 24.38 ? 275 ILE B CG1 1 ATOM 6212 C CG2 . ILE B 1 275 ? 27.226 3.622 15.822 1.00 24.16 ? 275 ILE B CG2 1 ATOM 6213 C CD1 . ILE B 1 275 ? 26.884 6.622 14.675 1.00 22.97 ? 275 ILE B CD1 1 ATOM 6214 N N . ALA B 1 276 ? 30.828 3.768 17.186 1.00 24.77 ? 276 ALA B N 1 ATOM 6215 C CA . ALA B 1 276 ? 31.363 2.952 18.290 1.00 24.50 ? 276 ALA B CA 1 ATOM 6216 C C . ALA B 1 276 ? 31.534 3.824 19.556 1.00 24.10 ? 276 ALA B C 1 ATOM 6217 O O . ALA B 1 276 ? 31.291 3.369 20.679 1.00 23.90 ? 276 ALA B O 1 ATOM 6218 C CB . ALA B 1 276 ? 32.689 2.283 17.895 1.00 25.05 ? 276 ALA B CB 1 ATOM 6219 N N . GLU B 1 277 ? 31.928 5.077 19.352 1.00 24.58 ? 277 GLU B N 1 ATOM 6220 C CA . GLU B 1 277 ? 32.032 6.054 20.429 1.00 24.94 ? 277 GLU B CA 1 ATOM 6221 C C . GLU B 1 277 ? 30.659 6.359 21.059 1.00 24.50 ? 277 GLU B C 1 ATOM 6222 O O . GLU B 1 277 ? 30.537 6.492 22.278 1.00 23.31 ? 277 GLU B O 1 ATOM 6223 C CB . GLU B 1 277 ? 32.644 7.336 19.885 1.00 25.76 ? 277 GLU B CB 1 ATOM 6224 C CG . GLU B 1 277 ? 32.873 8.396 20.923 1.00 29.09 ? 277 GLU B CG 1 ATOM 6225 C CD . GLU B 1 277 ? 33.811 9.479 20.430 1.00 34.58 ? 277 GLU B CD 1 ATOM 6226 O OE1 . GLU B 1 277 ? 33.387 10.346 19.621 1.00 37.05 ? 277 GLU B OE1 1 ATOM 6227 O OE2 . GLU B 1 277 ? 34.978 9.454 20.859 1.00 35.91 ? 277 GLU B OE2 1 ATOM 6228 N N . SER B 1 278 ? 29.626 6.450 20.218 1.00 23.98 ? 278 SER B N 1 ATOM 6229 C CA . SER B 1 278 ? 28.266 6.686 20.711 1.00 23.64 ? 278 SER B CA 1 ATOM 6230 C C . SER B 1 278 ? 27.751 5.519 21.518 1.00 23.42 ? 278 SER B C 1 ATOM 6231 O O . SER B 1 278 ? 27.085 5.710 22.531 1.00 23.93 ? 278 SER B O 1 ATOM 6232 C CB . SER B 1 278 ? 27.319 7.009 19.564 1.00 23.51 ? 278 SER B CB 1 ATOM 6233 O OG . SER B 1 278 ? 27.663 8.269 19.033 1.00 23.37 ? 278 SER B OG 1 ATOM 6234 N N . ILE B 1 279 ? 28.072 4.313 21.075 1.00 22.60 ? 279 ILE B N 1 ATOM 6235 C CA . ILE B 1 279 ? 27.716 3.109 21.803 1.00 22.37 ? 279 ILE B CA 1 ATOM 6236 C C . ILE B 1 279 ? 28.381 3.047 23.197 1.00 22.83 ? 279 ILE B C 1 ATOM 6237 O O . ILE B 1 279 ? 27.753 2.613 24.167 1.00 22.52 ? 279 ILE B O 1 ATOM 6238 C CB . ILE B 1 279 ? 28.040 1.867 20.964 1.00 22.01 ? 279 ILE B CB 1 ATOM 6239 C CG1 . ILE B 1 279 ? 27.112 1.805 19.735 1.00 21.97 ? 279 ILE B CG1 1 ATOM 6240 C CG2 . ILE B 1 279 ? 27.920 0.582 21.787 1.00 21.74 ? 279 ILE B CG2 1 ATOM 6241 C CD1 . ILE B 1 279 ? 25.648 1.477 20.046 1.00 18.56 ? 279 ILE B CD1 1 ATOM 6242 N N . ARG B 1 280 ? 29.640 3.480 23.300 1.00 22.66 ? 280 ARG B N 1 ATOM 6243 C CA . ARG B 1 280 ? 30.308 3.507 24.611 1.00 22.70 ? 280 ARG B CA 1 ATOM 6244 C C . ARG B 1 280 ? 29.673 4.568 25.507 1.00 22.45 ? 280 ARG B C 1 ATOM 6245 O O . ARG B 1 280 ? 29.452 4.345 26.708 1.00 22.57 ? 280 ARG B O 1 ATOM 6246 C CB . ARG B 1 280 ? 31.822 3.730 24.448 1.00 21.93 ? 280 ARG B CB 1 ATOM 6247 C CG . ARG B 1 280 ? 32.471 2.527 23.831 1.00 22.97 ? 280 ARG B CG 1 ATOM 6248 C CD . ARG B 1 280 ? 34.004 2.578 23.804 1.00 26.74 ? 280 ARG B CD 1 ATOM 6249 N NE . ARG B 1 280 ? 34.488 1.196 23.808 1.00 30.98 ? 280 ARG B NE 1 ATOM 6250 C CZ . ARG B 1 280 ? 34.743 0.505 22.709 1.00 32.36 ? 280 ARG B CZ 1 ATOM 6251 N NH1 . ARG B 1 280 ? 34.595 1.101 21.531 1.00 36.60 ? 280 ARG B NH1 1 ATOM 6252 N NH2 . ARG B 1 280 ? 35.168 -0.751 22.779 1.00 31.79 ? 280 ARG B NH2 1 ATOM 6253 N N . MET B 1 281 ? 29.356 5.707 24.906 1.00 22.38 ? 281 MET B N 1 ATOM 6254 C CA . MET B 1 281 ? 28.624 6.763 25.593 1.00 23.33 ? 281 MET B CA 1 ATOM 6255 C C . MET B 1 281 ? 27.275 6.240 26.123 1.00 23.62 ? 281 MET B C 1 ATOM 6256 O O . MET B 1 281 ? 26.914 6.481 27.293 1.00 23.56 ? 281 MET B O 1 ATOM 6257 C CB . MET B 1 281 ? 28.465 7.985 24.665 1.00 23.24 ? 281 MET B CB 1 ATOM 6258 C CG . MET B 1 281 ? 27.529 9.075 25.160 1.00 25.12 ? 281 MET B CG 1 ATOM 6259 S SD . MET B 1 281 ? 28.075 10.000 26.619 1.00 31.24 ? 281 MET B SD 1 ATOM 6260 C CE . MET B 1 281 ? 29.569 10.815 25.989 1.00 27.72 ? 281 MET B CE 1 ATOM 6261 N N . ALA B 1 282 ? 26.542 5.506 25.282 1.00 24.42 ? 282 ALA B N 1 ATOM 6262 C CA . ALA B 1 282 ? 25.242 4.929 25.698 1.00 25.01 ? 282 ALA B CA 1 ATOM 6263 C C . ALA B 1 282 ? 25.364 4.012 26.915 1.00 25.61 ? 282 ALA B C 1 ATOM 6264 O O . ALA B 1 282 ? 24.583 4.149 27.882 1.00 25.37 ? 282 ALA B O 1 ATOM 6265 C CB . ALA B 1 282 ? 24.558 4.195 24.547 1.00 23.81 ? 282 ALA B CB 1 ATOM 6266 N N . MET B 1 283 ? 26.329 3.082 26.874 1.00 25.80 ? 283 MET B N 1 ATOM 6267 C CA . MET B 1 283 ? 26.599 2.218 28.030 1.00 27.43 ? 283 MET B CA 1 ATOM 6268 C C . MET B 1 283 ? 26.882 3.029 29.297 1.00 26.76 ? 283 MET B C 1 ATOM 6269 O O . MET B 1 283 ? 26.306 2.752 30.358 1.00 27.82 ? 283 MET B O 1 ATOM 6270 C CB . MET B 1 283 ? 27.742 1.227 27.753 1.00 27.78 ? 283 MET B CB 1 ATOM 6271 C CG . MET B 1 283 ? 27.431 0.241 26.626 1.00 31.10 ? 283 MET B CG 1 ATOM 6272 S SD . MET B 1 283 ? 28.684 -1.039 26.406 1.00 38.76 ? 283 MET B SD 1 ATOM 6273 C CE . MET B 1 283 ? 29.909 -0.102 25.532 1.00 34.25 ? 283 MET B CE 1 ATOM 6274 N N . GLY B 1 284 ? 27.744 4.034 29.185 1.00 26.48 ? 284 GLY B N 1 ATOM 6275 C CA . GLY B 1 284 ? 28.057 4.908 30.324 1.00 25.84 ? 284 GLY B CA 1 ATOM 6276 C C . GLY B 1 284 ? 26.836 5.638 30.878 1.00 26.28 ? 284 GLY B C 1 ATOM 6277 O O . GLY B 1 284 ? 26.660 5.767 32.101 1.00 25.22 ? 284 GLY B O 1 ATOM 6278 N N . LEU B 1 285 ? 25.996 6.135 29.973 1.00 25.88 ? 285 LEU B N 1 ATOM 6279 C CA . LEU B 1 285 ? 24.796 6.865 30.365 1.00 25.99 ? 285 LEU B CA 1 ATOM 6280 C C . LEU B 1 285 ? 23.817 5.935 31.072 1.00 26.13 ? 285 LEU B C 1 ATOM 6281 O O . LEU B 1 285 ? 23.094 6.362 31.993 1.00 25.77 ? 285 LEU B O 1 ATOM 6282 C CB . LEU B 1 285 ? 24.145 7.495 29.131 1.00 25.37 ? 285 LEU B CB 1 ATOM 6283 C CG . LEU B 1 285 ? 24.252 8.997 28.803 1.00 25.73 ? 285 LEU B CG 1 ATOM 6284 C CD1 . LEU B 1 285 ? 25.259 9.808 29.623 1.00 22.49 ? 285 LEU B CD1 1 ATOM 6285 C CD2 . LEU B 1 285 ? 24.380 9.249 27.304 1.00 23.36 ? 285 LEU B CD2 1 ATOM 6286 N N . ARG B 1 286 ? 23.793 4.670 30.647 1.00 26.51 ? 286 ARG B N 1 ATOM 6287 C CA . ARG B 1 286 ? 22.934 3.664 31.287 1.00 27.35 ? 286 ARG B CA 1 ATOM 6288 C C . ARG B 1 286 ? 23.355 3.333 32.726 1.00 27.78 ? 286 ARG B C 1 ATOM 6289 O O . ARG B 1 286 ? 22.494 3.108 33.576 1.00 27.16 ? 286 ARG B O 1 ATOM 6290 C CB . ARG B 1 286 ? 22.886 2.373 30.490 1.00 27.67 ? 286 ARG B CB 1 ATOM 6291 C CG . ARG B 1 286 ? 22.087 2.448 29.205 1.00 29.86 ? 286 ARG B CG 1 ATOM 6292 C CD . ARG B 1 286 ? 21.326 1.169 29.041 1.00 31.71 ? 286 ARG B CD 1 ATOM 6293 N NE . ARG B 1 286 ? 20.068 1.275 29.736 1.00 33.86 ? 286 ARG B NE 1 ATOM 6294 C CZ . ARG B 1 286 ? 19.439 0.291 30.365 1.00 34.41 ? 286 ARG B CZ 1 ATOM 6295 N NH1 . ARG B 1 286 ? 19.942 -0.936 30.433 1.00 34.19 ? 286 ARG B NH1 1 ATOM 6296 N NH2 . ARG B 1 286 ? 18.283 0.561 30.947 1.00 35.97 ? 286 ARG B NH2 1 ATOM 6297 N N . ILE B 1 287 ? 24.672 3.276 32.973 1.00 27.89 ? 287 ILE B N 1 ATOM 6298 C CA . ILE B 1 287 ? 25.226 3.083 34.328 1.00 28.48 ? 287 ILE B CA 1 ATOM 6299 C C . ILE B 1 287 ? 24.889 4.267 35.230 1.00 28.21 ? 287 ILE B C 1 ATOM 6300 O O . ILE B 1 287 ? 24.493 4.083 36.374 1.00 28.85 ? 287 ILE B O 1 ATOM 6301 C CB . ILE B 1 287 ? 26.790 2.937 34.314 1.00 28.41 ? 287 ILE B CB 1 ATOM 6302 C CG1 . ILE B 1 287 ? 27.247 1.690 33.539 1.00 29.09 ? 287 ILE B CG1 1 ATOM 6303 C CG2 . ILE B 1 287 ? 27.368 2.952 35.740 1.00 29.80 ? 287 ILE B CG2 1 ATOM 6304 C CD1 . ILE B 1 287 ? 26.659 0.375 34.039 1.00 31.79 ? 287 ILE B CD1 1 ATOM 6305 N N . LYS B 1 288 ? 25.081 5.473 34.701 1.00 27.94 ? 288 LYS B N 1 ATOM 6306 C CA . LYS B 1 288 ? 24.919 6.703 35.449 1.00 28.39 ? 288 LYS B CA 1 ATOM 6307 C C . LYS B 1 288 ? 23.430 7.008 35.678 1.00 27.67 ? 288 LYS B C 1 ATOM 6308 O O . LYS B 1 288 ? 23.048 7.497 36.735 1.00 25.96 ? 288 LYS B O 1 ATOM 6309 C CB . LYS B 1 288 ? 25.588 7.854 34.700 1.00 28.98 ? 288 LYS B CB 1 ATOM 6310 C CG . LYS B 1 288 ? 26.386 8.820 35.594 1.00 33.45 ? 288 LYS B CG 1 ATOM 6311 C CD . LYS B 1 288 ? 26.526 10.207 34.938 1.00 38.23 ? 288 LYS B CD 1 ATOM 6312 C CE . LYS B 1 288 ? 27.314 11.214 35.818 1.00 41.48 ? 288 LYS B CE 1 ATOM 6313 N NZ . LYS B 1 288 ? 27.455 12.581 35.156 1.00 42.55 ? 288 LYS B NZ 1 ATOM 6314 N N . PHE B 1 289 ? 22.597 6.701 34.686 1.00 26.55 ? 289 PHE B N 1 ATOM 6315 C CA . PHE B 1 289 ? 21.176 7.024 34.772 1.00 26.67 ? 289 PHE B CA 1 ATOM 6316 C C . PHE B 1 289 ? 20.272 5.837 34.439 1.00 26.41 ? 289 PHE B C 1 ATOM 6317 O O . PHE B 1 289 ? 19.501 5.931 33.474 1.00 26.42 ? 289 PHE B O 1 ATOM 6318 C CB . PHE B 1 289 ? 20.860 8.180 33.813 1.00 26.35 ? 289 PHE B CB 1 ATOM 6319 C CG . PHE B 1 289 ? 21.541 9.460 34.156 1.00 26.29 ? 289 PHE B CG 1 ATOM 6320 C CD1 . PHE B 1 289 ? 21.011 10.306 35.125 1.00 27.94 ? 289 PHE B CD1 1 ATOM 6321 C CD2 . PHE B 1 289 ? 22.704 9.843 33.495 1.00 26.96 ? 289 PHE B CD2 1 ATOM 6322 C CE1 . PHE B 1 289 ? 21.627 11.507 35.439 1.00 27.00 ? 289 PHE B CE1 1 ATOM 6323 C CE2 . PHE B 1 289 ? 23.331 11.036 33.806 1.00 27.87 ? 289 PHE B CE2 1 ATOM 6324 C CZ . PHE B 1 289 ? 22.789 11.873 34.784 1.00 28.98 ? 289 PHE B CZ 1 ATOM 6325 N N . PRO B 1 290 ? 20.331 4.731 35.238 1.00 26.68 ? 290 PRO B N 1 ATOM 6326 C CA . PRO B 1 290 ? 19.638 3.506 34.812 1.00 26.65 ? 290 PRO B CA 1 ATOM 6327 C C . PRO B 1 290 ? 18.109 3.667 34.766 1.00 26.40 ? 290 PRO B C 1 ATOM 6328 O O . PRO B 1 290 ? 17.424 2.909 34.082 1.00 27.30 ? 290 PRO B O 1 ATOM 6329 C CB . PRO B 1 290 ? 20.067 2.478 35.878 1.00 26.71 ? 290 PRO B CB 1 ATOM 6330 C CG . PRO B 1 290 ? 20.338 3.304 37.095 1.00 26.85 ? 290 PRO B CG 1 ATOM 6331 C CD . PRO B 1 290 ? 20.984 4.543 36.556 1.00 26.38 ? 290 PRO B CD 1 ATOM 6332 N N . THR B 1 291 ? 17.611 4.689 35.450 1.00 26.06 ? 291 THR B N 1 ATOM 6333 C CA . THR B 1 291 ? 16.193 4.995 35.599 1.00 25.96 ? 291 THR B CA 1 ATOM 6334 C C . THR B 1 291 ? 15.635 5.927 34.475 1.00 25.52 ? 291 THR B C 1 ATOM 6335 O O . THR B 1 291 ? 14.424 6.032 34.277 1.00 25.39 ? 291 THR B O 1 ATOM 6336 C CB . THR B 1 291 ? 16.027 5.649 37.020 1.00 25.76 ? 291 THR B CB 1 ATOM 6337 O OG1 . THR B 1 291 ? 15.157 4.866 37.831 1.00 29.22 ? 291 THR B OG1 1 ATOM 6338 C CG2 . THR B 1 291 ? 15.591 7.077 36.978 1.00 26.22 ? 291 THR B CG2 1 ATOM 6339 N N . VAL B 1 292 ? 16.532 6.598 33.761 1.00 24.30 ? 292 VAL B N 1 ATOM 6340 C CA . VAL B 1 292 ? 16.204 7.648 32.794 1.00 23.65 ? 292 VAL B CA 1 ATOM 6341 C C . VAL B 1 292 ? 16.529 7.214 31.340 1.00 23.23 ? 292 VAL B C 1 ATOM 6342 O O . VAL B 1 292 ? 15.755 7.490 30.427 1.00 23.04 ? 292 VAL B O 1 ATOM 6343 C CB . VAL B 1 292 ? 16.989 8.943 33.088 1.00 23.41 ? 292 VAL B CB 1 ATOM 6344 C CG1 . VAL B 1 292 ? 16.568 10.085 32.138 1.00 23.29 ? 292 VAL B CG1 1 ATOM 6345 C CG2 . VAL B 1 292 ? 16.801 9.386 34.537 1.00 24.72 ? 292 VAL B CG2 1 ATOM 6346 N N . VAL B 1 293 ? 17.674 6.563 31.138 1.00 22.46 ? 293 VAL B N 1 ATOM 6347 C CA . VAL B 1 293 ? 18.135 6.189 29.787 1.00 22.33 ? 293 VAL B CA 1 ATOM 6348 C C . VAL B 1 293 ? 17.760 4.751 29.509 1.00 22.55 ? 293 VAL B C 1 ATOM 6349 O O . VAL B 1 293 ? 18.203 3.829 30.216 1.00 22.98 ? 293 VAL B O 1 ATOM 6350 C CB . VAL B 1 293 ? 19.665 6.411 29.605 1.00 22.74 ? 293 VAL B CB 1 ATOM 6351 C CG1 . VAL B 1 293 ? 20.185 5.761 28.296 1.00 22.76 ? 293 VAL B CG1 1 ATOM 6352 C CG2 . VAL B 1 293 ? 19.976 7.896 29.619 1.00 20.59 ? 293 VAL B CG2 1 ATOM 6353 N N . ALA B 1 294 ? 16.910 4.562 28.497 1.00 22.06 ? 294 ALA B N 1 ATOM 6354 C CA . ALA B 1 294 ? 16.427 3.238 28.141 1.00 21.21 ? 294 ALA B CA 1 ATOM 6355 C C . ALA B 1 294 ? 17.355 2.453 27.209 1.00 19.87 ? 294 ALA B C 1 ATOM 6356 O O . ALA B 1 294 ? 17.298 1.248 27.191 1.00 20.26 ? 294 ALA B O 1 ATOM 6357 C CB . ALA B 1 294 ? 14.976 3.292 27.570 1.00 20.98 ? 294 ALA B CB 1 ATOM 6358 N N . GLY B 1 295 ? 18.183 3.137 26.432 1.00 19.77 ? 295 GLY B N 1 ATOM 6359 C CA . GLY B 1 295 ? 18.955 2.474 25.365 1.00 19.00 ? 295 GLY B CA 1 ATOM 6360 C C . GLY B 1 295 ? 19.342 3.395 24.217 1.00 18.07 ? 295 GLY B C 1 ATOM 6361 O O . GLY B 1 295 ? 19.412 4.595 24.396 1.00 18.01 ? 295 GLY B O 1 ATOM 6362 N N . PHE B 1 296 ? 19.573 2.814 23.038 1.00 18.30 ? 296 PHE B N 1 ATOM 6363 C CA . PHE B 1 296 ? 20.183 3.514 21.904 1.00 18.71 ? 296 PHE B CA 1 ATOM 6364 C C . PHE B 1 296 ? 19.420 3.239 20.598 1.00 19.13 ? 296 PHE B C 1 ATOM 6365 O O . PHE B 1 296 ? 18.813 2.182 20.447 1.00 19.91 ? 296 PHE B O 1 ATOM 6366 C CB . PHE B 1 296 ? 21.643 3.031 21.751 1.00 18.89 ? 296 PHE B CB 1 ATOM 6367 C CG . PHE B 1 296 ? 22.410 3.702 20.640 1.00 18.33 ? 296 PHE B CG 1 ATOM 6368 C CD1 . PHE B 1 296 ? 22.629 3.051 19.441 1.00 21.54 ? 296 PHE B CD1 1 ATOM 6369 C CD2 . PHE B 1 296 ? 22.936 4.982 20.816 1.00 19.45 ? 296 PHE B CD2 1 ATOM 6370 C CE1 . PHE B 1 296 ? 23.389 3.671 18.415 1.00 22.28 ? 296 PHE B CE1 1 ATOM 6371 C CE2 . PHE B 1 296 ? 23.669 5.609 19.814 1.00 20.79 ? 296 PHE B CE2 1 ATOM 6372 C CZ . PHE B 1 296 ? 23.890 4.951 18.602 1.00 21.62 ? 296 PHE B CZ 1 ATOM 6373 N N . ASP B 1 297 ? 19.472 4.191 19.660 1.00 19.43 ? 297 ASP B N 1 ATOM 6374 C CA . ASP B 1 297 ? 18.836 4.056 18.338 1.00 19.41 ? 297 ASP B CA 1 ATOM 6375 C C . ASP B 1 297 ? 19.663 4.830 17.335 1.00 19.06 ? 297 ASP B C 1 ATOM 6376 O O . ASP B 1 297 ? 20.394 5.730 17.707 1.00 19.23 ? 297 ASP B O 1 ATOM 6377 C CB . ASP B 1 297 ? 17.402 4.633 18.377 1.00 19.12 ? 297 ASP B CB 1 ATOM 6378 C CG . ASP B 1 297 ? 16.626 4.495 17.031 1.00 21.07 ? 297 ASP B CG 1 ATOM 6379 O OD1 . ASP B 1 297 ? 17.070 3.754 16.100 1.00 19.69 ? 297 ASP B OD1 1 ATOM 6380 O OD2 . ASP B 1 297 ? 15.520 5.126 16.915 1.00 17.77 ? 297 ASP B OD2 1 ATOM 6381 N N . LEU B 1 298 ? 19.520 4.487 16.060 1.00 18.67 ? 298 LEU B N 1 ATOM 6382 C CA . LEU B 1 298 ? 20.166 5.203 14.958 1.00 19.26 ? 298 LEU B CA 1 ATOM 6383 C C . LEU B 1 298 ? 19.081 5.856 14.103 1.00 19.92 ? 298 LEU B C 1 ATOM 6384 O O . LEU B 1 298 ? 18.096 5.202 13.734 1.00 20.49 ? 298 LEU B O 1 ATOM 6385 C CB . LEU B 1 298 ? 20.994 4.222 14.112 1.00 19.16 ? 298 LEU B CB 1 ATOM 6386 C CG . LEU B 1 298 ? 22.310 3.794 14.779 1.00 20.41 ? 298 LEU B CG 1 ATOM 6387 C CD1 . LEU B 1 298 ? 22.855 2.484 14.205 1.00 18.81 ? 298 LEU B CD1 1 ATOM 6388 C CD2 . LEU B 1 298 ? 23.345 4.916 14.662 1.00 21.59 ? 298 LEU B CD2 1 ATOM 6389 N N . VAL B 1 299 ? 19.253 7.141 13.821 1.00 19.85 ? 299 VAL B N 1 ATOM 6390 C CA . VAL B 1 299 ? 18.238 7.951 13.149 1.00 19.87 ? 299 VAL B CA 1 ATOM 6391 C C . VAL B 1 299 ? 18.765 8.593 11.870 1.00 20.36 ? 299 VAL B C 1 ATOM 6392 O O . VAL B 1 299 ? 19.965 8.514 11.577 1.00 19.62 ? 299 VAL B O 1 ATOM 6393 C CB . VAL B 1 299 ? 17.664 9.049 14.080 1.00 20.06 ? 299 VAL B CB 1 ATOM 6394 C CG1 . VAL B 1 299 ? 16.981 8.392 15.277 1.00 18.96 ? 299 VAL B CG1 1 ATOM 6395 C CG2 . VAL B 1 299 ? 18.750 10.047 14.543 1.00 17.58 ? 299 VAL B CG2 1 ATOM 6396 N N . GLY B 1 300 ? 17.872 9.244 11.124 1.00 19.94 ? 300 GLY B N 1 ATOM 6397 C CA . GLY B 1 300 ? 18.232 9.816 9.816 1.00 20.89 ? 300 GLY B CA 1 ATOM 6398 C C . GLY B 1 300 ? 17.587 9.076 8.648 1.00 21.10 ? 300 GLY B C 1 ATOM 6399 O O . GLY B 1 300 ? 16.911 8.056 8.846 1.00 21.93 ? 300 GLY B O 1 ATOM 6400 N N . HIS B 1 301 ? 17.789 9.591 7.437 1.00 20.85 ? 301 HIS B N 1 ATOM 6401 C CA . HIS B 1 301 ? 17.195 9.050 6.211 1.00 20.86 ? 301 HIS B CA 1 ATOM 6402 C C . HIS B 1 301 ? 17.713 7.636 5.945 1.00 21.28 ? 301 HIS B C 1 ATOM 6403 O O . HIS B 1 301 ? 18.886 7.447 5.627 1.00 21.17 ? 301 HIS B O 1 ATOM 6404 C CB . HIS B 1 301 ? 17.503 9.989 5.030 1.00 21.12 ? 301 HIS B CB 1 ATOM 6405 C CG . HIS B 1 301 ? 16.678 9.730 3.796 1.00 20.86 ? 301 HIS B CG 1 ATOM 6406 N ND1 . HIS B 1 301 ? 15.585 8.884 3.778 1.00 20.90 ? 301 HIS B ND1 1 ATOM 6407 C CD2 . HIS B 1 301 ? 16.772 10.240 2.546 1.00 19.26 ? 301 HIS B CD2 1 ATOM 6408 C CE1 . HIS B 1 301 ? 15.052 8.876 2.570 1.00 20.31 ? 301 HIS B CE1 1 ATOM 6409 N NE2 . HIS B 1 301 ? 15.746 9.697 1.807 1.00 23.80 ? 301 HIS B NE2 1 ATOM 6410 N N . GLU B 1 302 ? 16.840 6.643 6.082 1.00 20.47 ? 302 GLU B N 1 ATOM 6411 C CA . GLU B 1 302 ? 17.280 5.239 6.074 1.00 20.58 ? 302 GLU B CA 1 ATOM 6412 C C . GLU B 1 302 ? 17.696 4.742 4.687 1.00 20.81 ? 302 GLU B C 1 ATOM 6413 O O . GLU B 1 302 ? 18.604 3.912 4.561 1.00 20.20 ? 302 GLU B O 1 ATOM 6414 C CB . GLU B 1 302 ? 16.176 4.338 6.613 1.00 20.98 ? 302 GLU B CB 1 ATOM 6415 C CG . GLU B 1 302 ? 16.678 2.929 6.992 1.00 19.88 ? 302 GLU B CG 1 ATOM 6416 C CD . GLU B 1 302 ? 15.591 2.050 7.625 1.00 22.07 ? 302 GLU B CD 1 ATOM 6417 O OE1 . GLU B 1 302 ? 14.507 2.584 8.004 1.00 18.65 ? 302 GLU B OE1 1 ATOM 6418 O OE2 . GLU B 1 302 ? 15.834 0.812 7.710 1.00 20.16 ? 302 GLU B OE2 1 ATOM 6419 N N . ASP B 1 303 ? 17.028 5.259 3.657 1.00 21.12 ? 303 ASP B N 1 ATOM 6420 C CA . ASP B 1 303 ? 17.333 4.892 2.278 1.00 22.19 ? 303 ASP B CA 1 ATOM 6421 C C . ASP B 1 303 ? 18.766 5.276 1.880 1.00 22.77 ? 303 ASP B C 1 ATOM 6422 O O . ASP B 1 303 ? 19.408 4.560 1.127 1.00 22.21 ? 303 ASP B O 1 ATOM 6423 C CB . ASP B 1 303 ? 16.341 5.527 1.296 1.00 21.69 ? 303 ASP B CB 1 ATOM 6424 C CG . ASP B 1 303 ? 15.031 4.740 1.180 1.00 22.79 ? 303 ASP B CG 1 ATOM 6425 O OD1 . ASP B 1 303 ? 14.882 3.697 1.849 1.00 23.26 ? 303 ASP B OD1 1 ATOM 6426 O OD2 . ASP B 1 303 ? 14.151 5.155 0.395 1.00 22.90 ? 303 ASP B OD2 1 ATOM 6427 N N . THR B 1 304 ? 19.241 6.405 2.398 1.00 23.80 ? 304 THR B N 1 ATOM 6428 C CA . THR B 1 304 ? 20.529 6.979 1.981 1.00 24.53 ? 304 THR B CA 1 ATOM 6429 C C . THR B 1 304 ? 21.674 6.848 2.991 1.00 24.93 ? 304 THR B C 1 ATOM 6430 O O . THR B 1 304 ? 22.801 7.242 2.687 1.00 25.75 ? 304 THR B O 1 ATOM 6431 C CB . THR B 1 304 ? 20.374 8.471 1.584 1.00 24.32 ? 304 THR B CB 1 ATOM 6432 O OG1 . THR B 1 304 ? 19.803 9.185 2.668 1.00 24.28 ? 304 THR B OG1 1 ATOM 6433 C CG2 . THR B 1 304 ? 19.464 8.647 0.384 1.00 24.79 ? 304 THR B CG2 1 ATOM 6434 N N . GLY B 1 305 ? 21.412 6.307 4.183 1.00 25.15 ? 305 GLY B N 1 ATOM 6435 C CA . GLY B 1 305 ? 22.465 6.172 5.194 1.00 24.70 ? 305 GLY B CA 1 ATOM 6436 C C . GLY B 1 305 ? 22.996 4.762 5.332 1.00 25.07 ? 305 GLY B C 1 ATOM 6437 O O . GLY B 1 305 ? 22.649 3.865 4.542 1.00 24.80 ? 305 GLY B O 1 ATOM 6438 N N . HIS B 1 306 ? 23.821 4.556 6.350 1.00 24.51 ? 306 HIS B N 1 ATOM 6439 C CA . HIS B 1 306 ? 24.394 3.250 6.592 1.00 24.97 ? 306 HIS B CA 1 ATOM 6440 C C . HIS B 1 306 ? 23.324 2.293 7.116 1.00 24.73 ? 306 HIS B C 1 ATOM 6441 O O . HIS B 1 306 ? 22.372 2.704 7.819 1.00 24.60 ? 306 HIS B O 1 ATOM 6442 C CB . HIS B 1 306 ? 25.554 3.344 7.582 1.00 25.31 ? 306 HIS B CB 1 ATOM 6443 C CG . HIS B 1 306 ? 26.821 3.876 6.990 1.00 28.87 ? 306 HIS B CG 1 ATOM 6444 N ND1 . HIS B 1 306 ? 27.351 5.101 7.344 1.00 33.36 ? 306 HIS B ND1 1 ATOM 6445 C CD2 . HIS B 1 306 ? 27.669 3.346 6.075 1.00 31.91 ? 306 HIS B CD2 1 ATOM 6446 C CE1 . HIS B 1 306 ? 28.474 5.300 6.674 1.00 34.27 ? 306 HIS B CE1 1 ATOM 6447 N NE2 . HIS B 1 306 ? 28.693 4.246 5.902 1.00 34.73 ? 306 HIS B NE2 1 ATOM 6448 N N . SER B 1 307 ? 23.477 1.027 6.757 1.00 23.90 ? 307 SER B N 1 ATOM 6449 C CA . SER B 1 307 ? 22.600 -0.025 7.246 1.00 23.08 ? 307 SER B CA 1 ATOM 6450 C C . SER B 1 307 ? 23.079 -0.476 8.626 1.00 23.59 ? 307 SER B C 1 ATOM 6451 O O . SER B 1 307 ? 24.215 -0.174 9.039 1.00 23.93 ? 307 SER B O 1 ATOM 6452 C CB . SER B 1 307 ? 22.640 -1.195 6.283 1.00 23.12 ? 307 SER B CB 1 ATOM 6453 O OG . SER B 1 307 ? 23.933 -1.794 6.309 1.00 20.28 ? 307 SER B OG 1 ATOM 6454 N N . LEU B 1 308 ? 22.224 -1.195 9.339 1.00 23.10 ? 308 LEU B N 1 ATOM 6455 C CA . LEU B 1 308 ? 22.607 -1.762 10.621 1.00 23.13 ? 308 LEU B CA 1 ATOM 6456 C C . LEU B 1 308 ? 23.762 -2.763 10.419 1.00 24.16 ? 308 LEU B C 1 ATOM 6457 O O . LEU B 1 308 ? 24.698 -2.795 11.207 1.00 23.95 ? 308 LEU B O 1 ATOM 6458 C CB . LEU B 1 308 ? 21.403 -2.420 11.309 1.00 22.40 ? 308 LEU B CB 1 ATOM 6459 C CG . LEU B 1 308 ? 20.212 -1.506 11.651 1.00 20.40 ? 308 LEU B CG 1 ATOM 6460 C CD1 . LEU B 1 308 ? 19.165 -2.299 12.409 1.00 21.50 ? 308 LEU B CD1 1 ATOM 6461 C CD2 . LEU B 1 308 ? 20.628 -0.281 12.445 1.00 15.34 ? 308 LEU B CD2 1 ATOM 6462 N N . HIS B 1 309 ? 23.694 -3.555 9.349 1.00 24.75 ? 309 HIS B N 1 ATOM 6463 C CA . HIS B 1 309 ? 24.791 -4.443 8.996 1.00 26.03 ? 309 HIS B CA 1 ATOM 6464 C C . HIS B 1 309 ? 26.149 -3.733 8.912 1.00 25.96 ? 309 HIS B C 1 ATOM 6465 O O . HIS B 1 309 ? 27.133 -4.239 9.430 1.00 26.09 ? 309 HIS B O 1 ATOM 6466 C CB . HIS B 1 309 ? 24.516 -5.200 7.688 1.00 26.83 ? 309 HIS B CB 1 ATOM 6467 C CG . HIS B 1 309 ? 25.612 -6.152 7.322 1.00 30.15 ? 309 HIS B CG 1 ATOM 6468 N ND1 . HIS B 1 309 ? 25.722 -7.407 7.881 1.00 32.99 ? 309 HIS B ND1 1 ATOM 6469 C CD2 . HIS B 1 309 ? 26.675 -6.013 6.492 1.00 33.45 ? 309 HIS B CD2 1 ATOM 6470 C CE1 . HIS B 1 309 ? 26.797 -8.009 7.400 1.00 34.70 ? 309 HIS B CE1 1 ATOM 6471 N NE2 . HIS B 1 309 ? 27.390 -7.185 6.553 1.00 35.55 ? 309 HIS B NE2 1 ATOM 6472 N N . ASP B 1 310 ? 26.196 -2.571 8.261 1.00 26.75 ? 310 ASP B N 1 ATOM 6473 C CA . ASP B 1 310 ? 27.416 -1.788 8.150 1.00 27.11 ? 310 ASP B CA 1 ATOM 6474 C C . ASP B 1 310 ? 27.998 -1.457 9.533 1.00 27.63 ? 310 ASP B C 1 ATOM 6475 O O . ASP B 1 310 ? 29.214 -1.267 9.678 1.00 27.14 ? 310 ASP B O 1 ATOM 6476 C CB . ASP B 1 310 ? 27.167 -0.467 7.413 1.00 26.85 ? 310 ASP B CB 1 ATOM 6477 C CG . ASP B 1 310 ? 26.749 -0.641 5.947 1.00 28.57 ? 310 ASP B CG 1 ATOM 6478 O OD1 . ASP B 1 310 ? 26.973 -1.717 5.344 1.00 26.08 ? 310 ASP B OD1 1 ATOM 6479 O OD2 . ASP B 1 310 ? 26.205 0.351 5.388 1.00 29.29 ? 310 ASP B OD2 1 ATOM 6480 N N . TYR B 1 311 ? 27.125 -1.356 10.536 1.00 27.08 ? 311 TYR B N 1 ATOM 6481 C CA . TYR B 1 311 ? 27.538 -0.930 11.871 1.00 26.84 ? 311 TYR B CA 1 ATOM 6482 C C . TYR B 1 311 ? 27.754 -2.095 12.804 1.00 27.17 ? 311 TYR B C 1 ATOM 6483 O O . TYR B 1 311 ? 27.883 -1.897 14.021 1.00 27.31 ? 311 TYR B O 1 ATOM 6484 C CB . TYR B 1 311 ? 26.472 -0.032 12.495 1.00 26.61 ? 311 TYR B CB 1 ATOM 6485 C CG . TYR B 1 311 ? 26.419 1.366 11.960 1.00 24.78 ? 311 TYR B CG 1 ATOM 6486 C CD1 . TYR B 1 311 ? 27.560 2.148 11.899 1.00 23.02 ? 311 TYR B CD1 1 ATOM 6487 C CD2 . TYR B 1 311 ? 25.204 1.933 11.556 1.00 22.91 ? 311 TYR B CD2 1 ATOM 6488 C CE1 . TYR B 1 311 ? 27.516 3.456 11.406 1.00 21.64 ? 311 TYR B CE1 1 ATOM 6489 C CE2 . TYR B 1 311 ? 25.149 3.255 11.082 1.00 19.84 ? 311 TYR B CE2 1 ATOM 6490 C CZ . TYR B 1 311 ? 26.317 4.007 11.012 1.00 21.95 ? 311 TYR B CZ 1 ATOM 6491 O OH . TYR B 1 311 ? 26.302 5.317 10.549 1.00 21.62 ? 311 TYR B OH 1 ATOM 6492 N N . LYS B 1 312 ? 27.784 -3.304 12.255 1.00 28.22 ? 312 LYS B N 1 ATOM 6493 C CA . LYS B 1 312 ? 27.803 -4.508 13.088 1.00 30.34 ? 312 LYS B CA 1 ATOM 6494 C C . LYS B 1 312 ? 28.889 -4.464 14.163 1.00 30.42 ? 312 LYS B C 1 ATOM 6495 O O . LYS B 1 312 ? 28.639 -4.846 15.310 1.00 31.38 ? 312 LYS B O 1 ATOM 6496 C CB . LYS B 1 312 ? 27.966 -5.774 12.256 1.00 30.54 ? 312 LYS B CB 1 ATOM 6497 C CG . LYS B 1 312 ? 27.632 -7.032 13.061 1.00 34.05 ? 312 LYS B CG 1 ATOM 6498 C CD . LYS B 1 312 ? 27.524 -8.293 12.187 1.00 39.38 ? 312 LYS B CD 1 ATOM 6499 C CE . LYS B 1 312 ? 28.747 -9.198 12.333 1.00 41.54 ? 312 LYS B CE 1 ATOM 6500 N NZ . LYS B 1 312 ? 28.423 -10.579 11.834 1.00 43.85 ? 312 LYS B NZ 1 ATOM 6501 N N . GLU B 1 313 ? 30.077 -3.994 13.780 1.00 30.65 ? 313 GLU B N 1 ATOM 6502 C CA . GLU B 1 313 ? 31.221 -3.972 14.682 1.00 31.60 ? 313 GLU B CA 1 ATOM 6503 C C . GLU B 1 313 ? 30.940 -3.121 15.916 1.00 30.43 ? 313 GLU B C 1 ATOM 6504 O O . GLU B 1 313 ? 31.133 -3.604 17.035 1.00 31.03 ? 313 GLU B O 1 ATOM 6505 C CB . GLU B 1 313 ? 32.495 -3.522 13.958 1.00 32.39 ? 313 GLU B CB 1 ATOM 6506 C CG . GLU B 1 313 ? 33.024 -4.583 12.962 1.00 36.87 ? 313 GLU B CG 1 ATOM 6507 C CD . GLU B 1 313 ? 33.375 -5.918 13.634 1.00 42.62 ? 313 GLU B CD 1 ATOM 6508 O OE1 . GLU B 1 313 ? 34.194 -5.916 14.583 1.00 46.63 ? 313 GLU B OE1 1 ATOM 6509 O OE2 . GLU B 1 313 ? 32.848 -6.970 13.207 1.00 45.11 ? 313 GLU B OE2 1 ATOM 6510 N N . ALA B 1 314 ? 30.463 -1.889 15.709 1.00 28.23 ? 314 ALA B N 1 ATOM 6511 C CA . ALA B 1 314 ? 30.052 -1.004 16.818 1.00 27.34 ? 314 ALA B CA 1 ATOM 6512 C C . ALA B 1 314 ? 28.900 -1.571 17.665 1.00 27.18 ? 314 ALA B C 1 ATOM 6513 O O . ALA B 1 314 ? 28.969 -1.587 18.911 1.00 26.30 ? 314 ALA B O 1 ATOM 6514 C CB . ALA B 1 314 ? 29.689 0.393 16.287 1.00 26.80 ? 314 ALA B CB 1 ATOM 6515 N N . LEU B 1 315 ? 27.847 -2.036 16.987 1.00 26.66 ? 315 LEU B N 1 ATOM 6516 C CA . LEU B 1 315 ? 26.625 -2.500 17.650 1.00 26.98 ? 315 LEU B CA 1 ATOM 6517 C C . LEU B 1 315 ? 26.805 -3.759 18.494 1.00 27.68 ? 315 LEU B C 1 ATOM 6518 O O . LEU B 1 315 ? 25.960 -4.059 19.347 1.00 26.73 ? 315 LEU B O 1 ATOM 6519 C CB . LEU B 1 315 ? 25.470 -2.666 16.621 1.00 26.20 ? 315 LEU B CB 1 ATOM 6520 C CG . LEU B 1 315 ? 25.111 -1.330 15.923 1.00 25.34 ? 315 LEU B CG 1 ATOM 6521 C CD1 . LEU B 1 315 ? 24.080 -1.503 14.827 1.00 26.19 ? 315 LEU B CD1 1 ATOM 6522 C CD2 . LEU B 1 315 ? 24.620 -0.283 16.943 1.00 24.47 ? 315 LEU B CD2 1 ATOM 6523 N N . MET B 1 316 ? 27.900 -4.480 18.241 1.00 29.03 ? 316 MET B N 1 ATOM 6524 C CA . MET B 1 316 ? 28.282 -5.677 19.021 1.00 30.69 ? 316 MET B CA 1 ATOM 6525 C C . MET B 1 316 ? 29.219 -5.382 20.209 1.00 31.66 ? 316 MET B C 1 ATOM 6526 O O . MET B 1 316 ? 29.547 -6.293 20.976 1.00 31.97 ? 316 MET B O 1 ATOM 6527 C CB . MET B 1 316 ? 28.957 -6.736 18.123 1.00 30.92 ? 316 MET B CB 1 ATOM 6528 C CG . MET B 1 316 ? 28.071 -7.384 17.062 1.00 31.58 ? 316 MET B CG 1 ATOM 6529 S SD . MET B 1 316 ? 26.482 -7.920 17.718 1.00 35.20 ? 316 MET B SD 1 ATOM 6530 C CE . MET B 1 316 ? 26.921 -9.250 18.858 1.00 33.58 ? 316 MET B CE 1 ATOM 6531 N N . ILE B 1 317 ? 29.675 -4.137 20.340 1.00 32.34 ? 317 ILE B N 1 ATOM 6532 C CA . ILE B 1 317 ? 30.566 -3.753 21.454 1.00 33.91 ? 317 ILE B CA 1 ATOM 6533 C C . ILE B 1 317 ? 29.998 -4.163 22.830 1.00 35.05 ? 317 ILE B C 1 ATOM 6534 O O . ILE B 1 317 ? 30.704 -4.800 23.615 1.00 35.23 ? 317 ILE B O 1 ATOM 6535 C CB . ILE B 1 317 ? 30.965 -2.252 21.389 1.00 33.33 ? 317 ILE B CB 1 ATOM 6536 C CG1 . ILE B 1 317 ? 31.993 -2.040 20.284 1.00 32.85 ? 317 ILE B CG1 1 ATOM 6537 C CG2 . ILE B 1 317 ? 31.497 -1.731 22.736 1.00 34.06 ? 317 ILE B CG2 1 ATOM 6538 C CD1 . ILE B 1 317 ? 32.247 -0.584 19.936 1.00 30.90 ? 317 ILE B CD1 1 ATOM 6539 N N . PRO B 1 318 ? 28.716 -3.845 23.118 1.00 36.18 ? 318 PRO B N 1 ATOM 6540 C CA . PRO B 1 318 ? 28.221 -4.250 24.445 1.00 37.11 ? 318 PRO B CA 1 ATOM 6541 C C . PRO B 1 318 ? 28.284 -5.765 24.699 1.00 38.38 ? 318 PRO B C 1 ATOM 6542 O O . PRO B 1 318 ? 28.706 -6.198 25.787 1.00 38.86 ? 318 PRO B O 1 ATOM 6543 C CB . PRO B 1 318 ? 26.777 -3.733 24.462 1.00 36.90 ? 318 PRO B CB 1 ATOM 6544 C CG . PRO B 1 318 ? 26.782 -2.590 23.488 1.00 36.42 ? 318 PRO B CG 1 ATOM 6545 C CD . PRO B 1 318 ? 27.752 -2.976 22.409 1.00 36.27 ? 318 PRO B CD 1 ATOM 6546 N N . ALA B 1 319 ? 27.882 -6.566 23.717 1.00 39.14 ? 319 ALA B N 1 ATOM 6547 C CA . ALA B 1 319 ? 27.961 -8.017 23.860 1.00 40.73 ? 319 ALA B CA 1 ATOM 6548 C C . ALA B 1 319 ? 29.421 -8.499 24.062 1.00 41.70 ? 319 ALA B C 1 ATOM 6549 O O . ALA B 1 319 ? 29.696 -9.314 24.954 1.00 42.19 ? 319 ALA B O 1 ATOM 6550 C CB . ALA B 1 319 ? 27.306 -8.706 22.677 1.00 40.42 ? 319 ALA B CB 1 ATOM 6551 N N . LYS B 1 320 ? 30.348 -7.973 23.258 1.00 42.38 ? 320 LYS B N 1 ATOM 6552 C CA . LYS B 1 320 ? 31.779 -8.301 23.392 1.00 43.05 ? 320 LYS B CA 1 ATOM 6553 C C . LYS B 1 320 ? 32.356 -7.833 24.750 1.00 43.43 ? 320 LYS B C 1 ATOM 6554 O O . LYS B 1 320 ? 33.283 -8.452 25.275 1.00 43.44 ? 320 LYS B O 1 ATOM 6555 C CB . LYS B 1 320 ? 32.589 -7.742 22.205 1.00 43.25 ? 320 LYS B CB 1 ATOM 6556 C CG . LYS B 1 320 ? 32.194 -8.337 20.830 1.00 43.83 ? 320 LYS B CG 1 ATOM 6557 C CD . LYS B 1 320 ? 32.942 -7.705 19.625 1.00 46.21 ? 320 LYS B CD 1 ATOM 6558 C CE . LYS B 1 320 ? 32.487 -6.265 19.319 1.00 48.46 ? 320 LYS B CE 1 ATOM 6559 N NZ . LYS B 1 320 ? 33.120 -5.641 18.112 1.00 47.74 ? 320 LYS B NZ 1 ATOM 6560 N N . ASP B 1 321 ? 31.794 -6.753 25.307 1.00 43.28 ? 321 ASP B N 1 ATOM 6561 C CA . ASP B 1 321 ? 32.131 -6.272 26.657 1.00 43.19 ? 321 ASP B CA 1 ATOM 6562 C C . ASP B 1 321 ? 31.268 -6.883 27.768 1.00 42.33 ? 321 ASP B C 1 ATOM 6563 O O . ASP B 1 321 ? 31.355 -6.450 28.910 1.00 42.81 ? 321 ASP B O 1 ATOM 6564 C CB . ASP B 1 321 ? 32.062 -4.733 26.742 1.00 43.24 ? 321 ASP B CB 1 ATOM 6565 C CG . ASP B 1 321 ? 33.210 -4.039 25.999 1.00 45.79 ? 321 ASP B CG 1 ATOM 6566 O OD1 . ASP B 1 321 ? 33.998 -4.730 25.309 1.00 48.39 ? 321 ASP B OD1 1 ATOM 6567 O OD2 . ASP B 1 321 ? 33.326 -2.794 26.095 1.00 46.17 ? 321 ASP B OD2 1 ATOM 6568 N N . GLY B 1 322 ? 30.440 -7.874 27.443 1.00 41.53 ? 322 GLY B N 1 ATOM 6569 C CA . GLY B 1 322 ? 29.592 -8.541 28.445 1.00 40.10 ? 322 GLY B CA 1 ATOM 6570 C C . GLY B 1 322 ? 28.374 -7.793 28.996 1.00 39.71 ? 322 GLY B C 1 ATOM 6571 O O . GLY B 1 322 ? 27.829 -8.188 30.038 1.00 39.68 ? 322 GLY B O 1 ATOM 6572 N N . VAL B 1 323 ? 27.925 -6.737 28.302 1.00 38.31 ? 323 VAL B N 1 ATOM 6573 C CA . VAL B 1 323 ? 26.815 -5.892 28.772 1.00 36.69 ? 323 VAL B CA 1 ATOM 6574 C C . VAL B 1 323 ? 25.629 -5.899 27.787 1.00 35.57 ? 323 VAL B C 1 ATOM 6575 O O . VAL B 1 323 ? 25.818 -5.986 26.578 1.00 35.18 ? 323 VAL B O 1 ATOM 6576 C CB . VAL B 1 323 ? 27.282 -4.426 28.953 1.00 37.25 ? 323 VAL B CB 1 ATOM 6577 C CG1 . VAL B 1 323 ? 26.167 -3.546 29.556 1.00 37.79 ? 323 VAL B CG1 1 ATOM 6578 C CG2 . VAL B 1 323 ? 28.566 -4.346 29.805 1.00 38.16 ? 323 VAL B CG2 1 ATOM 6579 N N . LYS B 1 324 ? 24.414 -5.798 28.313 1.00 33.88 ? 324 LYS B N 1 ATOM 6580 C CA . LYS B 1 324 ? 23.212 -5.667 27.486 1.00 32.33 ? 324 LYS B CA 1 ATOM 6581 C C . LYS B 1 324 ? 22.916 -4.169 27.260 1.00 30.01 ? 324 LYS B C 1 ATOM 6582 O O . LYS B 1 324 ? 22.595 -3.447 28.200 1.00 29.73 ? 324 LYS B O 1 ATOM 6583 C CB . LYS B 1 324 ? 22.036 -6.371 28.185 1.00 33.22 ? 324 LYS B CB 1 ATOM 6584 C CG . LYS B 1 324 ? 20.687 -6.250 27.471 1.00 36.66 ? 324 LYS B CG 1 ATOM 6585 C CD . LYS B 1 324 ? 19.757 -7.403 27.822 1.00 41.09 ? 324 LYS B CD 1 ATOM 6586 C CE . LYS B 1 324 ? 18.963 -7.138 29.104 1.00 43.72 ? 324 LYS B CE 1 ATOM 6587 N NZ . LYS B 1 324 ? 17.974 -8.238 29.359 1.00 46.13 ? 324 LYS B NZ 1 ATOM 6588 N N . LEU B 1 325 ? 23.088 -3.689 26.038 1.00 27.04 ? 325 LEU B N 1 ATOM 6589 C CA . LEU B 1 325 ? 22.590 -2.360 25.702 1.00 25.14 ? 325 LEU B CA 1 ATOM 6590 C C . LEU B 1 325 ? 21.271 -2.489 24.894 1.00 23.88 ? 325 LEU B C 1 ATOM 6591 O O . LEU B 1 325 ? 21.273 -2.938 23.760 1.00 24.07 ? 325 LEU B O 1 ATOM 6592 C CB . LEU B 1 325 ? 23.635 -1.515 24.961 1.00 24.86 ? 325 LEU B CB 1 ATOM 6593 C CG . LEU B 1 325 ? 23.191 -0.159 24.347 1.00 24.13 ? 325 LEU B CG 1 ATOM 6594 C CD1 . LEU B 1 325 ? 22.806 0.891 25.421 1.00 20.46 ? 325 LEU B CD1 1 ATOM 6595 C CD2 . LEU B 1 325 ? 24.276 0.357 23.410 1.00 23.03 ? 325 LEU B CD2 1 ATOM 6596 N N . PRO B 1 326 ? 20.142 -2.102 25.496 1.00 22.82 ? 326 PRO B N 1 ATOM 6597 C CA . PRO B 1 326 ? 18.873 -2.248 24.781 1.00 21.60 ? 326 PRO B CA 1 ATOM 6598 C C . PRO B 1 326 ? 18.862 -1.355 23.541 1.00 20.75 ? 326 PRO B C 1 ATOM 6599 O O . PRO B 1 326 ? 19.396 -0.249 23.563 1.00 20.04 ? 326 PRO B O 1 ATOM 6600 C CB . PRO B 1 326 ? 17.829 -1.782 25.807 1.00 21.41 ? 326 PRO B CB 1 ATOM 6601 C CG . PRO B 1 326 ? 18.567 -1.882 27.177 1.00 22.39 ? 326 PRO B CG 1 ATOM 6602 C CD . PRO B 1 326 ? 19.963 -1.494 26.829 1.00 22.52 ? 326 PRO B CD 1 ATOM 6603 N N . TYR B 1 327 ? 18.294 -1.878 22.461 1.00 20.27 ? 327 TYR B N 1 ATOM 6604 C CA . TYR B 1 327 ? 18.185 -1.158 21.210 1.00 19.70 ? 327 TYR B CA 1 ATOM 6605 C C . TYR B 1 327 ? 16.697 -0.915 20.854 1.00 18.97 ? 327 TYR B C 1 ATOM 6606 O O . TYR B 1 327 ? 15.834 -1.690 21.236 1.00 18.12 ? 327 TYR B O 1 ATOM 6607 C CB . TYR B 1 327 ? 18.901 -1.943 20.089 1.00 19.10 ? 327 TYR B CB 1 ATOM 6608 C CG . TYR B 1 327 ? 20.447 -1.980 20.211 1.00 19.93 ? 327 TYR B CG 1 ATOM 6609 C CD1 . TYR B 1 327 ? 21.180 -0.811 20.363 1.00 19.88 ? 327 TYR B CD1 1 ATOM 6610 C CD2 . TYR B 1 327 ? 21.153 -3.189 20.115 1.00 20.66 ? 327 TYR B CD2 1 ATOM 6611 C CE1 . TYR B 1 327 ? 22.587 -0.826 20.446 1.00 22.86 ? 327 TYR B CE1 1 ATOM 6612 C CE2 . TYR B 1 327 ? 22.572 -3.223 20.195 1.00 21.12 ? 327 TYR B CE2 1 ATOM 6613 C CZ . TYR B 1 327 ? 23.277 -2.042 20.364 1.00 23.37 ? 327 TYR B CZ 1 ATOM 6614 O OH . TYR B 1 327 ? 24.663 -2.040 20.452 1.00 24.47 ? 327 TYR B OH 1 ATOM 6615 N N . PHE B 1 328 ? 16.453 0.175 20.136 1.00 17.93 ? 328 PHE B N 1 ATOM 6616 C CA . PHE B 1 328 ? 15.113 0.589 19.674 1.00 18.14 ? 328 PHE B CA 1 ATOM 6617 C C . PHE B 1 328 ? 15.207 1.037 18.207 1.00 17.22 ? 328 PHE B C 1 ATOM 6618 O O . PHE B 1 328 ? 14.850 2.147 17.878 1.00 19.31 ? 328 PHE B O 1 ATOM 6619 C CB . PHE B 1 328 ? 14.577 1.721 20.601 1.00 17.48 ? 328 PHE B CB 1 ATOM 6620 C CG . PHE B 1 328 ? 14.483 1.295 22.053 1.00 19.47 ? 328 PHE B CG 1 ATOM 6621 C CD1 . PHE B 1 328 ? 13.323 0.697 22.543 1.00 18.21 ? 328 PHE B CD1 1 ATOM 6622 C CD2 . PHE B 1 328 ? 15.591 1.411 22.902 1.00 19.44 ? 328 PHE B CD2 1 ATOM 6623 C CE1 . PHE B 1 328 ? 13.250 0.265 23.864 1.00 20.82 ? 328 PHE B CE1 1 ATOM 6624 C CE2 . PHE B 1 328 ? 15.530 0.988 24.240 1.00 19.96 ? 328 PHE B CE2 1 ATOM 6625 C CZ . PHE B 1 328 ? 14.379 0.384 24.724 1.00 18.90 ? 328 PHE B CZ 1 ATOM 6626 N N . PHE B 1 329 ? 15.682 0.170 17.318 1.00 17.66 ? 329 PHE B N 1 ATOM 6627 C CA . PHE B 1 329 ? 16.067 0.610 15.967 1.00 16.85 ? 329 PHE B CA 1 ATOM 6628 C C . PHE B 1 329 ? 14.888 1.057 15.071 1.00 16.59 ? 329 PHE B C 1 ATOM 6629 O O . PHE B 1 329 ? 13.954 0.302 14.890 1.00 16.91 ? 329 PHE B O 1 ATOM 6630 C CB . PHE B 1 329 ? 16.864 -0.486 15.246 1.00 16.43 ? 329 PHE B CB 1 ATOM 6631 C CG . PHE B 1 329 ? 18.244 -0.756 15.844 1.00 17.35 ? 329 PHE B CG 1 ATOM 6632 C CD1 . PHE B 1 329 ? 19.215 0.240 15.906 1.00 16.22 ? 329 PHE B CD1 1 ATOM 6633 C CD2 . PHE B 1 329 ? 18.562 -2.021 16.338 1.00 16.55 ? 329 PHE B CD2 1 ATOM 6634 C CE1 . PHE B 1 329 ? 20.483 -0.027 16.480 1.00 17.00 ? 329 PHE B CE1 1 ATOM 6635 C CE2 . PHE B 1 329 ? 19.837 -2.292 16.884 1.00 14.39 ? 329 PHE B CE2 1 ATOM 6636 C CZ . PHE B 1 329 ? 20.772 -1.319 16.961 1.00 14.52 ? 329 PHE B CZ 1 ATOM 6637 N N . HIS B 1 330 ? 14.952 2.277 14.531 1.00 16.27 ? 330 HIS B N 1 ATOM 6638 C CA . HIS B 1 330 ? 14.310 2.577 13.252 1.00 17.05 ? 330 HIS B CA 1 ATOM 6639 C C . HIS B 1 330 ? 14.758 1.513 12.237 1.00 16.64 ? 330 HIS B C 1 ATOM 6640 O O . HIS B 1 330 ? 15.957 1.272 12.092 1.00 16.52 ? 330 HIS B O 1 ATOM 6641 C CB . HIS B 1 330 ? 14.775 3.920 12.710 1.00 16.82 ? 330 HIS B CB 1 ATOM 6642 C CG . HIS B 1 330 ? 14.121 5.105 13.337 1.00 19.41 ? 330 HIS B CG 1 ATOM 6643 N ND1 . HIS B 1 330 ? 14.312 5.450 14.656 1.00 18.35 ? 330 HIS B ND1 1 ATOM 6644 C CD2 . HIS B 1 330 ? 13.327 6.070 12.803 1.00 19.42 ? 330 HIS B CD2 1 ATOM 6645 C CE1 . HIS B 1 330 ? 13.639 6.555 14.918 1.00 19.35 ? 330 HIS B CE1 1 ATOM 6646 N NE2 . HIS B 1 330 ? 13.029 6.945 13.813 1.00 18.85 ? 330 HIS B NE2 1 ATOM 6647 N N . ALA B 1 331 ? 13.804 0.903 11.539 1.00 15.72 ? 331 ALA B N 1 ATOM 6648 C CA . ALA B 1 331 ? 14.107 -0.104 10.534 1.00 15.92 ? 331 ALA B CA 1 ATOM 6649 C C . ALA B 1 331 ? 12.962 -0.340 9.556 1.00 15.78 ? 331 ALA B C 1 ATOM 6650 O O . ALA B 1 331 ? 11.792 -0.457 9.949 1.00 15.51 ? 331 ALA B O 1 ATOM 6651 C CB . ALA B 1 331 ? 14.483 -1.446 11.211 1.00 15.24 ? 331 ALA B CB 1 ATOM 6652 N N . GLY B 1 332 ? 13.324 -0.470 8.287 1.00 15.64 ? 332 GLY B N 1 ATOM 6653 C CA . GLY B 1 332 ? 12.382 -0.756 7.219 1.00 16.16 ? 332 GLY B CA 1 ATOM 6654 C C . GLY B 1 332 ? 11.444 0.396 6.892 1.00 15.84 ? 332 GLY B C 1 ATOM 6655 O O . GLY B 1 332 ? 10.340 0.175 6.385 1.00 15.87 ? 332 GLY B O 1 ATOM 6656 N N . GLU B 1 333 ? 11.873 1.611 7.214 1.00 15.79 ? 333 GLU B N 1 ATOM 6657 C CA . GLU B 1 333 ? 11.160 2.840 6.825 1.00 15.39 ? 333 GLU B CA 1 ATOM 6658 C C . GLU B 1 333 ? 11.464 3.174 5.367 1.00 15.05 ? 333 GLU B C 1 ATOM 6659 O O . GLU B 1 333 ? 12.272 4.061 5.074 1.00 15.76 ? 333 GLU B O 1 ATOM 6660 C CB . GLU B 1 333 ? 11.551 3.984 7.766 1.00 16.25 ? 333 GLU B CB 1 ATOM 6661 C CG . GLU B 1 333 ? 10.638 5.212 7.679 1.00 17.66 ? 333 GLU B CG 1 ATOM 6662 C CD . GLU B 1 333 ? 11.192 6.433 8.385 1.00 22.65 ? 333 GLU B CD 1 ATOM 6663 O OE1 . GLU B 1 333 ? 12.176 6.332 9.173 1.00 23.39 ? 333 GLU B OE1 1 ATOM 6664 O OE2 . GLU B 1 333 ? 10.609 7.517 8.173 1.00 24.31 ? 333 GLU B OE2 1 ATOM 6665 N N . THR B 1 334 ? 10.869 2.403 4.454 1.00 14.43 ? 334 THR B N 1 ATOM 6666 C CA . THR B 1 334 ? 11.265 2.390 3.039 1.00 14.26 ? 334 THR B CA 1 ATOM 6667 C C . THR B 1 334 ? 10.234 1.718 2.164 1.00 14.31 ? 334 THR B C 1 ATOM 6668 O O . THR B 1 334 ? 9.493 0.805 2.612 1.00 14.51 ? 334 THR B O 1 ATOM 6669 C CB . THR B 1 334 ? 12.634 1.677 2.815 1.00 14.85 ? 334 THR B CB 1 ATOM 6670 O OG1 . THR B 1 334 ? 13.035 1.821 1.448 1.00 16.35 ? 334 THR B OG1 1 ATOM 6671 C CG2 . THR B 1 334 ? 12.536 0.178 3.175 1.00 13.68 ? 334 THR B CG2 1 ATOM 6672 N N . ASP B 1 335 ? 10.165 2.201 0.923 1.00 14.50 ? 335 ASP B N 1 ATOM 6673 C CA . ASP B 1 335 ? 9.335 1.620 -0.129 1.00 15.28 ? 335 ASP B CA 1 ATOM 6674 C C . ASP B 1 335 ? 10.033 0.515 -0.850 1.00 15.67 ? 335 ASP B C 1 ATOM 6675 O O . ASP B 1 335 ? 9.374 -0.235 -1.571 1.00 16.21 ? 335 ASP B O 1 ATOM 6676 C CB . ASP B 1 335 ? 8.942 2.667 -1.189 1.00 14.00 ? 335 ASP B CB 1 ATOM 6677 C CG . ASP B 1 335 ? 7.902 3.631 -0.675 1.00 15.20 ? 335 ASP B CG 1 ATOM 6678 O OD1 . ASP B 1 335 ? 6.998 3.149 0.039 1.00 14.74 ? 335 ASP B OD1 1 ATOM 6679 O OD2 . ASP B 1 335 ? 7.977 4.855 -0.975 1.00 13.19 ? 335 ASP B OD2 1 ATOM 6680 N N . TRP B 1 336 ? 11.359 0.427 -0.709 1.00 15.21 ? 336 TRP B N 1 ATOM 6681 C CA . TRP B 1 336 ? 12.092 -0.616 -1.417 1.00 15.80 ? 336 TRP B CA 1 ATOM 6682 C C . TRP B 1 336 ? 11.816 -1.962 -0.755 1.00 16.19 ? 336 TRP B C 1 ATOM 6683 O O . TRP B 1 336 ? 11.421 -2.026 0.431 1.00 16.91 ? 336 TRP B O 1 ATOM 6684 C CB . TRP B 1 336 ? 13.610 -0.310 -1.462 1.00 15.37 ? 336 TRP B CB 1 ATOM 6685 C CG . TRP B 1 336 ? 13.935 0.975 -2.173 1.00 16.33 ? 336 TRP B CG 1 ATOM 6686 C CD1 . TRP B 1 336 ? 14.376 2.143 -1.599 1.00 18.33 ? 336 TRP B CD1 1 ATOM 6687 C CD2 . TRP B 1 336 ? 13.805 1.251 -3.582 1.00 18.58 ? 336 TRP B CD2 1 ATOM 6688 N NE1 . TRP B 1 336 ? 14.542 3.114 -2.564 1.00 17.83 ? 336 TRP B NE1 1 ATOM 6689 C CE2 . TRP B 1 336 ? 14.203 2.597 -3.785 1.00 19.53 ? 336 TRP B CE2 1 ATOM 6690 C CE3 . TRP B 1 336 ? 13.403 0.493 -4.687 1.00 18.32 ? 336 TRP B CE3 1 ATOM 6691 C CZ2 . TRP B 1 336 ? 14.204 3.201 -5.058 1.00 19.78 ? 336 TRP B CZ2 1 ATOM 6692 C CZ3 . TRP B 1 336 ? 13.403 1.086 -5.941 1.00 18.99 ? 336 TRP B CZ3 1 ATOM 6693 C CH2 . TRP B 1 336 ? 13.802 2.424 -6.118 1.00 17.92 ? 336 TRP B CH2 1 ATOM 6694 N N . GLN B 1 337 ? 11.982 -3.022 -1.535 1.00 15.48 ? 337 GLN B N 1 ATOM 6695 C CA . GLN B 1 337 ? 11.730 -4.383 -1.075 1.00 16.61 ? 337 GLN B CA 1 ATOM 6696 C C . GLN B 1 337 ? 12.826 -5.295 -1.625 1.00 16.48 ? 337 GLN B C 1 ATOM 6697 O O . GLN B 1 337 ? 13.161 -5.226 -2.815 1.00 15.89 ? 337 GLN B O 1 ATOM 6698 C CB . GLN B 1 337 ? 10.368 -4.895 -1.590 1.00 15.37 ? 337 GLN B CB 1 ATOM 6699 C CG . GLN B 1 337 ? 10.069 -6.341 -1.219 1.00 17.93 ? 337 GLN B CG 1 ATOM 6700 C CD . GLN B 1 337 ? 8.877 -6.966 -1.959 1.00 18.96 ? 337 GLN B CD 1 ATOM 6701 O OE1 . GLN B 1 337 ? 8.589 -8.155 -1.776 1.00 18.84 ? 337 GLN B OE1 1 ATOM 6702 N NE2 . GLN B 1 337 ? 8.188 -6.176 -2.791 1.00 16.24 ? 337 GLN B NE2 1 ATOM 6703 N N . GLY B 1 338 ? 13.329 -6.194 -0.775 1.00 17.76 ? 338 GLY B N 1 ATOM 6704 C CA . GLY B 1 338 ? 14.371 -7.121 -1.199 1.00 18.90 ? 338 GLY B CA 1 ATOM 6705 C C . GLY B 1 338 ? 15.752 -6.505 -1.226 1.00 20.01 ? 338 GLY B C 1 ATOM 6706 O O . GLY B 1 338 ? 16.686 -7.102 -1.770 1.00 20.75 ? 338 GLY B O 1 ATOM 6707 N N . THR B 1 339 ? 15.902 -5.334 -0.604 1.00 19.98 ? 339 THR B N 1 ATOM 6708 C CA . THR B 1 339 ? 17.172 -4.607 -0.615 1.00 20.29 ? 339 THR B CA 1 ATOM 6709 C C . THR B 1 339 ? 17.868 -4.628 0.746 1.00 20.35 ? 339 THR B C 1 ATOM 6710 O O . THR B 1 339 ? 17.294 -5.103 1.724 1.00 19.88 ? 339 THR B O 1 ATOM 6711 C CB . THR B 1 339 ? 16.970 -3.131 -1.029 1.00 20.21 ? 339 THR B CB 1 ATOM 6712 O OG1 . THR B 1 339 ? 16.292 -2.422 0.020 1.00 20.12 ? 339 THR B OG1 1 ATOM 6713 C CG2 . THR B 1 339 ? 16.173 -3.037 -2.341 1.00 19.54 ? 339 THR B CG2 1 ATOM 6714 N N . SER B 1 340 ? 19.088 -4.077 0.817 1.00 20.34 ? 340 SER B N 1 ATOM 6715 C CA . SER B 1 340 ? 19.763 -3.911 2.118 1.00 20.41 ? 340 SER B CA 1 ATOM 6716 C C . SER B 1 340 ? 18.996 -2.968 3.071 1.00 19.75 ? 340 SER B C 1 ATOM 6717 O O . SER B 1 340 ? 19.167 -3.037 4.275 1.00 17.97 ? 340 SER B O 1 ATOM 6718 C CB . SER B 1 340 ? 21.176 -3.381 1.930 1.00 20.67 ? 340 SER B CB 1 ATOM 6719 O OG . SER B 1 340 ? 21.136 -2.109 1.296 1.00 23.78 ? 340 SER B OG 1 ATOM 6720 N N . ILE B 1 341 ? 18.185 -2.065 2.531 1.00 19.81 ? 341 ILE B N 1 ATOM 6721 C CA . ILE B 1 341 ? 17.443 -1.157 3.412 1.00 20.11 ? 341 ILE B CA 1 ATOM 6722 C C . ILE B 1 341 ? 16.366 -1.889 4.218 1.00 19.46 ? 341 ILE B C 1 ATOM 6723 O O . ILE B 1 341 ? 16.340 -1.787 5.445 1.00 18.68 ? 341 ILE B O 1 ATOM 6724 C CB . ILE B 1 341 ? 16.859 0.059 2.642 1.00 19.79 ? 341 ILE B CB 1 ATOM 6725 C CG1 . ILE B 1 341 ? 17.966 0.715 1.809 1.00 21.76 ? 341 ILE B CG1 1 ATOM 6726 C CG2 . ILE B 1 341 ? 16.254 1.100 3.610 1.00 19.17 ? 341 ILE B CG2 1 ATOM 6727 C CD1 . ILE B 1 341 ? 17.452 1.449 0.569 1.00 22.73 ? 341 ILE B CD1 1 ATOM 6728 N N . ASP B 1 342 ? 15.489 -2.636 3.545 1.00 19.59 ? 342 ASP B N 1 ATOM 6729 C CA . ASP B 1 342 ? 14.428 -3.354 4.265 1.00 19.82 ? 342 ASP B CA 1 ATOM 6730 C C . ASP B 1 342 ? 14.938 -4.578 5.038 1.00 19.76 ? 342 ASP B C 1 ATOM 6731 O O . ASP B 1 342 ? 14.281 -5.048 5.984 1.00 19.39 ? 342 ASP B O 1 ATOM 6732 C CB . ASP B 1 342 ? 13.199 -3.662 3.372 1.00 19.72 ? 342 ASP B CB 1 ATOM 6733 C CG . ASP B 1 342 ? 13.552 -4.422 2.089 1.00 21.33 ? 342 ASP B CG 1 ATOM 6734 O OD1 . ASP B 1 342 ? 12.940 -5.478 1.847 1.00 23.97 ? 342 ASP B OD1 1 ATOM 6735 O OD2 . ASP B 1 342 ? 14.388 -3.955 1.286 1.00 20.94 ? 342 ASP B OD2 1 ATOM 6736 N N . ARG B 1 343 ? 16.141 -5.061 4.692 1.00 20.36 ? 343 ARG B N 1 ATOM 6737 C CA . ARG B 1 343 ? 16.813 -6.059 5.552 1.00 20.36 ? 343 ARG B CA 1 ATOM 6738 C C . ARG B 1 343 ? 17.214 -5.514 6.929 1.00 19.70 ? 343 ARG B C 1 ATOM 6739 O O . ARG B 1 343 ? 17.537 -6.283 7.811 1.00 20.45 ? 343 ARG B O 1 ATOM 6740 C CB . ARG B 1 343 ? 18.007 -6.740 4.858 1.00 20.30 ? 343 ARG B CB 1 ATOM 6741 C CG . ARG B 1 343 ? 17.577 -7.940 4.031 1.00 26.03 ? 343 ARG B CG 1 ATOM 6742 C CD . ARG B 1 343 ? 18.747 -8.814 3.544 1.00 26.40 ? 343 ARG B CD 1 ATOM 6743 N NE . ARG B 1 343 ? 19.730 -8.071 2.753 1.00 28.85 ? 343 ARG B NE 1 ATOM 6744 C CZ . ARG B 1 343 ? 19.594 -7.759 1.465 1.00 29.26 ? 343 ARG B CZ 1 ATOM 6745 N NH1 . ARG B 1 343 ? 18.511 -8.113 0.778 1.00 30.49 ? 343 ARG B NH1 1 ATOM 6746 N NH2 . ARG B 1 343 ? 20.543 -7.072 0.862 1.00 28.71 ? 343 ARG B NH2 1 ATOM 6747 N N . ASN B 1 344 ? 17.174 -4.197 7.123 1.00 20.25 ? 344 ASN B N 1 ATOM 6748 C CA . ASN B 1 344 ? 17.424 -3.637 8.457 1.00 19.12 ? 344 ASN B CA 1 ATOM 6749 C C . ASN B 1 344 ? 16.480 -4.162 9.521 1.00 19.16 ? 344 ASN B C 1 ATOM 6750 O O . ASN B 1 344 ? 16.817 -4.116 10.695 1.00 19.49 ? 344 ASN B O 1 ATOM 6751 C CB . ASN B 1 344 ? 17.383 -2.097 8.453 1.00 19.42 ? 344 ASN B CB 1 ATOM 6752 C CG . ASN B 1 344 ? 18.611 -1.472 7.827 1.00 19.94 ? 344 ASN B CG 1 ATOM 6753 O OD1 . ASN B 1 344 ? 19.725 -1.978 7.990 1.00 21.28 ? 344 ASN B OD1 1 ATOM 6754 N ND2 . ASN B 1 344 ? 18.419 -0.363 7.096 1.00 18.59 ? 344 ASN B ND2 1 ATOM 6755 N N . ILE B 1 345 ? 15.291 -4.645 9.141 1.00 18.45 ? 345 ILE B N 1 ATOM 6756 C CA . ILE B 1 345 ? 14.345 -5.131 10.144 1.00 17.82 ? 345 ILE B CA 1 ATOM 6757 C C . ILE B 1 345 ? 14.840 -6.474 10.715 1.00 18.53 ? 345 ILE B C 1 ATOM 6758 O O . ILE B 1 345 ? 14.832 -6.712 11.918 1.00 17.57 ? 345 ILE B O 1 ATOM 6759 C CB . ILE B 1 345 ? 12.896 -5.317 9.586 1.00 17.93 ? 345 ILE B CB 1 ATOM 6760 C CG1 . ILE B 1 345 ? 12.346 -4.025 8.948 1.00 16.69 ? 345 ILE B CG1 1 ATOM 6761 C CG2 . ILE B 1 345 ? 11.958 -5.799 10.699 1.00 17.35 ? 345 ILE B CG2 1 ATOM 6762 C CD1 . ILE B 1 345 ? 10.909 -4.190 8.325 1.00 15.45 ? 345 ILE B CD1 1 ATOM 6763 N N . LEU B 1 346 ? 15.237 -7.354 9.818 1.00 18.70 ? 346 LEU B N 1 ATOM 6764 C CA . LEU B 1 346 ? 15.816 -8.611 10.195 1.00 18.96 ? 346 LEU B CA 1 ATOM 6765 C C . LEU B 1 346 ? 17.038 -8.377 11.100 1.00 18.77 ? 346 LEU B C 1 ATOM 6766 O O . LEU B 1 346 ? 17.161 -9.024 12.143 1.00 19.05 ? 346 LEU B O 1 ATOM 6767 C CB . LEU B 1 346 ? 16.178 -9.397 8.929 1.00 19.39 ? 346 LEU B CB 1 ATOM 6768 C CG . LEU B 1 346 ? 17.096 -10.611 9.072 1.00 19.82 ? 346 LEU B CG 1 ATOM 6769 C CD1 . LEU B 1 346 ? 16.441 -11.690 9.905 1.00 19.76 ? 346 LEU B CD1 1 ATOM 6770 C CD2 . LEU B 1 346 ? 17.414 -11.142 7.694 1.00 21.86 ? 346 LEU B CD2 1 ATOM 6771 N N . ASP B 1 347 ? 17.898 -7.434 10.721 1.00 19.66 ? 347 ASP B N 1 ATOM 6772 C CA . ASP B 1 347 ? 19.114 -7.136 11.487 1.00 20.92 ? 347 ASP B CA 1 ATOM 6773 C C . ASP B 1 347 ? 18.834 -6.484 12.839 1.00 21.15 ? 347 ASP B C 1 ATOM 6774 O O . ASP B 1 347 ? 19.521 -6.785 13.823 1.00 21.16 ? 347 ASP B O 1 ATOM 6775 C CB . ASP B 1 347 ? 20.109 -6.324 10.662 1.00 21.31 ? 347 ASP B CB 1 ATOM 6776 C CG . ASP B 1 347 ? 20.847 -7.194 9.650 1.00 23.88 ? 347 ASP B CG 1 ATOM 6777 O OD1 . ASP B 1 347 ? 21.020 -8.397 9.944 1.00 23.07 ? 347 ASP B OD1 1 ATOM 6778 O OD2 . ASP B 1 347 ? 21.211 -6.690 8.563 1.00 26.12 ? 347 ASP B OD2 1 ATOM 6779 N N . ALA B 1 348 ? 17.816 -5.620 12.890 1.00 20.41 ? 348 ALA B N 1 ATOM 6780 C CA . ALA B 1 348 ? 17.346 -5.078 14.159 1.00 20.38 ? 348 ALA B CA 1 ATOM 6781 C C . ALA B 1 348 ? 16.989 -6.229 15.096 1.00 20.56 ? 348 ALA B C 1 ATOM 6782 O O . ALA B 1 348 ? 17.385 -6.228 16.277 1.00 21.19 ? 348 ALA B O 1 ATOM 6783 C CB . ALA B 1 348 ? 16.127 -4.178 13.949 1.00 19.06 ? 348 ALA B CB 1 ATOM 6784 N N . LEU B 1 349 ? 16.223 -7.183 14.580 1.00 20.78 ? 349 LEU B N 1 ATOM 6785 C CA . LEU B 1 349 ? 15.763 -8.339 15.372 1.00 22.10 ? 349 LEU B CA 1 ATOM 6786 C C . LEU B 1 349 ? 16.931 -9.255 15.828 1.00 22.94 ? 349 LEU B C 1 ATOM 6787 O O . LEU B 1 349 ? 16.921 -9.786 16.954 1.00 22.89 ? 349 LEU B O 1 ATOM 6788 C CB . LEU B 1 349 ? 14.758 -9.147 14.562 1.00 22.28 ? 349 LEU B CB 1 ATOM 6789 C CG . LEU B 1 349 ? 13.236 -9.193 14.816 1.00 24.19 ? 349 LEU B CG 1 ATOM 6790 C CD1 . LEU B 1 349 ? 12.700 -8.362 15.982 1.00 21.93 ? 349 LEU B CD1 1 ATOM 6791 C CD2 . LEU B 1 349 ? 12.455 -8.956 13.520 1.00 21.75 ? 349 LEU B CD2 1 ATOM 6792 N N . MET B 1 350 ? 17.903 -9.446 14.940 1.00 23.08 ? 350 MET B N 1 ATOM 6793 C CA . MET B 1 350 ? 19.124 -10.213 15.256 1.00 23.65 ? 350 MET B CA 1 ATOM 6794 C C . MET B 1 350 ? 19.964 -9.544 16.344 1.00 24.04 ? 350 MET B C 1 ATOM 6795 O O . MET B 1 350 ? 20.709 -10.210 17.072 1.00 24.20 ? 350 MET B O 1 ATOM 6796 C CB . MET B 1 350 ? 19.977 -10.430 13.999 1.00 23.95 ? 350 MET B CB 1 ATOM 6797 C CG . MET B 1 350 ? 19.361 -11.299 12.891 1.00 24.27 ? 350 MET B CG 1 ATOM 6798 S SD . MET B 1 350 ? 18.795 -12.932 13.379 1.00 27.93 ? 350 MET B SD 1 ATOM 6799 C CE . MET B 1 350 ? 17.088 -12.649 13.895 1.00 25.69 ? 350 MET B CE 1 ATOM 6800 N N . LEU B 1 351 ? 19.854 -8.219 16.434 1.00 23.51 ? 351 LEU B N 1 ATOM 6801 C CA . LEU B 1 351 ? 20.494 -7.452 17.492 1.00 22.98 ? 351 LEU B CA 1 ATOM 6802 C C . LEU B 1 351 ? 19.645 -7.274 18.766 1.00 22.57 ? 351 LEU B C 1 ATOM 6803 O O . LEU B 1 351 ? 19.972 -6.442 19.611 1.00 21.71 ? 351 LEU B O 1 ATOM 6804 C CB . LEU B 1 351 ? 20.988 -6.112 16.957 1.00 22.28 ? 351 LEU B CB 1 ATOM 6805 C CG . LEU B 1 351 ? 22.077 -6.161 15.883 1.00 23.78 ? 351 LEU B CG 1 ATOM 6806 C CD1 . LEU B 1 351 ? 22.168 -4.823 15.127 1.00 25.05 ? 351 LEU B CD1 1 ATOM 6807 C CD2 . LEU B 1 351 ? 23.445 -6.521 16.495 1.00 26.68 ? 351 LEU B CD2 1 ATOM 6808 N N . ASN B 1 352 ? 18.596 -8.094 18.901 1.00 22.87 ? 352 ASN B N 1 ATOM 6809 C CA . ASN B 1 352 ? 17.689 -8.115 20.064 1.00 23.53 ? 352 ASN B CA 1 ATOM 6810 C C . ASN B 1 352 ? 16.964 -6.799 20.366 1.00 22.28 ? 352 ASN B C 1 ATOM 6811 O O . ASN B 1 352 ? 16.760 -6.449 21.531 1.00 21.31 ? 352 ASN B O 1 ATOM 6812 C CB . ASN B 1 352 ? 18.421 -8.604 21.334 1.00 25.30 ? 352 ASN B CB 1 ATOM 6813 C CG . ASN B 1 352 ? 19.373 -9.752 21.051 1.00 30.02 ? 352 ASN B CG 1 ATOM 6814 O OD1 . ASN B 1 352 ? 19.124 -10.562 20.162 1.00 34.15 ? 352 ASN B OD1 1 ATOM 6815 N ND2 . ASN B 1 352 ? 20.480 -9.818 21.801 1.00 37.34 ? 352 ASN B ND2 1 ATOM 6816 N N . THR B 1 353 ? 16.573 -6.078 19.319 1.00 21.15 ? 353 THR B N 1 ATOM 6817 C CA . THR B 1 353 ? 15.879 -4.801 19.493 1.00 20.12 ? 353 THR B CA 1 ATOM 6818 C C . THR B 1 353 ? 14.617 -4.982 20.361 1.00 19.48 ? 353 THR B C 1 ATOM 6819 O O . THR B 1 353 ? 13.982 -6.008 20.285 1.00 20.06 ? 353 THR B O 1 ATOM 6820 C CB . THR B 1 353 ? 15.559 -4.173 18.122 1.00 19.80 ? 353 THR B CB 1 ATOM 6821 O OG1 . THR B 1 353 ? 15.264 -2.790 18.293 1.00 19.03 ? 353 THR B OG1 1 ATOM 6822 C CG2 . THR B 1 353 ? 14.366 -4.896 17.423 1.00 19.57 ? 353 THR B CG2 1 ATOM 6823 N N . THR B 1 354 ? 14.274 -3.993 21.187 1.00 19.64 ? 354 THR B N 1 ATOM 6824 C CA . THR B 1 354 ? 13.126 -4.081 22.101 1.00 19.07 ? 354 THR B CA 1 ATOM 6825 C C . THR B 1 354 ? 11.833 -3.700 21.363 1.00 18.72 ? 354 THR B C 1 ATOM 6826 O O . THR B 1 354 ? 10.792 -4.302 21.597 1.00 18.75 ? 354 THR B O 1 ATOM 6827 C CB . THR B 1 354 ? 13.330 -3.163 23.337 1.00 19.48 ? 354 THR B CB 1 ATOM 6828 O OG1 . THR B 1 354 ? 14.499 -3.565 24.063 1.00 21.39 ? 354 THR B OG1 1 ATOM 6829 C CG2 . THR B 1 354 ? 12.118 -3.152 24.290 1.00 18.53 ? 354 THR B CG2 1 ATOM 6830 N N . ARG B 1 355 ? 11.905 -2.663 20.514 1.00 17.84 ? 355 ARG B N 1 ATOM 6831 C CA . ARG B 1 355 ? 10.816 -2.267 19.600 1.00 16.94 ? 355 ARG B CA 1 ATOM 6832 C C . ARG B 1 355 ? 11.435 -1.938 18.221 1.00 16.75 ? 355 ARG B C 1 ATOM 6833 O O . ARG B 1 355 ? 12.617 -1.614 18.121 1.00 15.81 ? 355 ARG B O 1 ATOM 6834 C CB . ARG B 1 355 ? 10.046 -1.044 20.138 1.00 16.42 ? 355 ARG B CB 1 ATOM 6835 C CG . ARG B 1 355 ? 9.391 -1.231 21.540 1.00 14.98 ? 355 ARG B CG 1 ATOM 6836 C CD . ARG B 1 355 ? 8.376 -0.137 21.904 1.00 16.60 ? 355 ARG B CD 1 ATOM 6837 N NE . ARG B 1 355 ? 8.990 1.189 21.925 1.00 15.79 ? 355 ARG B NE 1 ATOM 6838 C CZ . ARG B 1 355 ? 9.529 1.771 22.989 1.00 16.52 ? 355 ARG B CZ 1 ATOM 6839 N NH1 . ARG B 1 355 ? 9.503 1.181 24.196 1.00 16.60 ? 355 ARG B NH1 1 ATOM 6840 N NH2 . ARG B 1 355 ? 10.080 2.964 22.844 1.00 15.18 ? 355 ARG B NH2 1 ATOM 6841 N N . ILE B 1 356 ? 10.626 -2.023 17.176 1.00 15.81 ? 356 ILE B N 1 ATOM 6842 C CA . ILE B 1 356 ? 11.029 -1.593 15.828 1.00 15.17 ? 356 ILE B CA 1 ATOM 6843 C C . ILE B 1 356 ? 10.361 -0.254 15.466 1.00 15.28 ? 356 ILE B C 1 ATOM 6844 O O . ILE B 1 356 ? 9.143 -0.157 15.442 1.00 15.67 ? 356 ILE B O 1 ATOM 6845 C CB . ILE B 1 356 ? 10.621 -2.649 14.800 1.00 15.16 ? 356 ILE B CB 1 ATOM 6846 C CG1 . ILE B 1 356 ? 11.279 -4.003 15.134 1.00 14.62 ? 356 ILE B CG1 1 ATOM 6847 C CG2 . ILE B 1 356 ? 10.939 -2.217 13.376 1.00 15.23 ? 356 ILE B CG2 1 ATOM 6848 C CD1 . ILE B 1 356 ? 10.551 -5.200 14.453 1.00 17.59 ? 356 ILE B CD1 1 ATOM 6849 N N . GLY B 1 357 ? 11.152 0.764 15.164 1.00 15.09 ? 357 GLY B N 1 ATOM 6850 C CA . GLY B 1 357 ? 10.578 2.044 14.666 1.00 15.38 ? 357 GLY B CA 1 ATOM 6851 C C . GLY B 1 357 ? 10.108 1.888 13.229 1.00 15.83 ? 357 GLY B C 1 ATOM 6852 O O . GLY B 1 357 ? 10.911 1.489 12.360 1.00 15.92 ? 357 GLY B O 1 ATOM 6853 N N . HIS B 1 358 ? 8.812 2.168 12.987 1.00 15.29 ? 358 HIS B N 1 ATOM 6854 C CA . HIS B 1 358 ? 8.150 1.996 11.677 1.00 15.01 ? 358 HIS B CA 1 ATOM 6855 C C . HIS B 1 358 ? 7.900 0.532 11.227 1.00 15.72 ? 358 HIS B C 1 ATOM 6856 O O . HIS B 1 358 ? 6.731 0.060 11.203 1.00 15.49 ? 358 HIS B O 1 ATOM 6857 C CB . HIS B 1 358 ? 8.848 2.804 10.565 1.00 15.45 ? 358 HIS B CB 1 ATOM 6858 C CG . HIS B 1 358 ? 8.974 4.269 10.872 1.00 16.22 ? 358 HIS B CG 1 ATOM 6859 N ND1 . HIS B 1 358 ? 7.916 5.146 10.755 1.00 14.57 ? 358 HIS B ND1 1 ATOM 6860 C CD2 . HIS B 1 358 ? 10.017 4.997 11.330 1.00 15.90 ? 358 HIS B CD2 1 ATOM 6861 C CE1 . HIS B 1 358 ? 8.307 6.352 11.117 1.00 15.22 ? 358 HIS B CE1 1 ATOM 6862 N NE2 . HIS B 1 358 ? 9.579 6.289 11.470 1.00 16.06 ? 358 HIS B NE2 1 ATOM 6863 N N . GLY B 1 359 ? 8.961 -0.176 10.836 1.00 15.11 ? 359 GLY B N 1 ATOM 6864 C CA . GLY B 1 359 ? 8.791 -1.530 10.273 1.00 15.00 ? 359 GLY B CA 1 ATOM 6865 C C . GLY B 1 359 ? 7.809 -1.501 9.100 1.00 14.81 ? 359 GLY B C 1 ATOM 6866 O O . GLY B 1 359 ? 7.057 -2.447 8.876 1.00 14.27 ? 359 GLY B O 1 ATOM 6867 N N . PHE B 1 360 ? 7.818 -0.389 8.352 1.00 15.32 ? 360 PHE B N 1 ATOM 6868 C CA . PHE B 1 360 ? 6.907 -0.163 7.220 1.00 14.29 ? 360 PHE B CA 1 ATOM 6869 C C . PHE B 1 360 ? 6.989 -1.336 6.231 1.00 15.24 ? 360 PHE B C 1 ATOM 6870 O O . PHE B 1 360 ? 5.982 -1.838 5.743 1.00 13.83 ? 360 PHE B O 1 ATOM 6871 C CB . PHE B 1 360 ? 7.283 1.175 6.566 1.00 14.14 ? 360 PHE B CB 1 ATOM 6872 C CG . PHE B 1 360 ? 6.383 1.587 5.413 1.00 12.59 ? 360 PHE B CG 1 ATOM 6873 C CD1 . PHE B 1 360 ? 6.648 1.151 4.121 1.00 11.37 ? 360 PHE B CD1 1 ATOM 6874 C CD2 . PHE B 1 360 ? 5.299 2.440 5.629 1.00 10.38 ? 360 PHE B CD2 1 ATOM 6875 C CE1 . PHE B 1 360 ? 5.856 1.521 3.053 1.00 11.69 ? 360 PHE B CE1 1 ATOM 6876 C CE2 . PHE B 1 360 ? 4.480 2.830 4.554 1.00 10.07 ? 360 PHE B CE2 1 ATOM 6877 C CZ . PHE B 1 360 ? 4.754 2.381 3.265 1.00 11.02 ? 360 PHE B CZ 1 ATOM 6878 N N . ALA B 1 361 ? 8.210 -1.828 6.005 1.00 15.33 ? 361 ALA B N 1 ATOM 6879 C CA . ALA B 1 361 ? 8.429 -2.917 5.059 1.00 16.55 ? 361 ALA B CA 1 ATOM 6880 C C . ALA B 1 361 ? 8.122 -4.337 5.634 1.00 17.22 ? 361 ALA B C 1 ATOM 6881 O O . ALA B 1 361 ? 8.258 -5.340 4.923 1.00 17.63 ? 361 ALA B O 1 ATOM 6882 C CB . ALA B 1 361 ? 9.903 -2.828 4.490 1.00 15.39 ? 361 ALA B CB 1 ATOM 6883 N N . LEU B 1 362 ? 7.698 -4.415 6.894 1.00 17.58 ? 362 LEU B N 1 ATOM 6884 C CA . LEU B 1 362 ? 7.519 -5.715 7.588 1.00 18.64 ? 362 LEU B CA 1 ATOM 6885 C C . LEU B 1 362 ? 6.577 -6.712 6.933 1.00 18.99 ? 362 LEU B C 1 ATOM 6886 O O . LEU B 1 362 ? 6.885 -7.919 6.866 1.00 18.98 ? 362 LEU B O 1 ATOM 6887 C CB . LEU B 1 362 ? 7.048 -5.501 9.026 1.00 18.31 ? 362 LEU B CB 1 ATOM 6888 C CG . LEU B 1 362 ? 7.544 -6.382 10.181 1.00 21.31 ? 362 LEU B CG 1 ATOM 6889 C CD1 . LEU B 1 362 ? 6.441 -6.729 11.193 1.00 17.03 ? 362 LEU B CD1 1 ATOM 6890 C CD2 . LEU B 1 362 ? 8.403 -7.617 9.790 1.00 17.45 ? 362 LEU B CD2 1 ATOM 6891 N N . SER B 1 363 ? 5.418 -6.231 6.479 1.00 19.12 ? 363 SER B N 1 ATOM 6892 C CA . SER B 1 363 ? 4.429 -7.114 5.842 1.00 19.05 ? 363 SER B CA 1 ATOM 6893 C C . SER B 1 363 ? 4.921 -7.840 4.564 1.00 19.00 ? 363 SER B C 1 ATOM 6894 O O . SER B 1 363 ? 4.276 -8.778 4.096 1.00 18.52 ? 363 SER B O 1 ATOM 6895 C CB . SER B 1 363 ? 3.141 -6.355 5.532 1.00 19.41 ? 363 SER B CB 1 ATOM 6896 O OG . SER B 1 363 ? 3.321 -5.456 4.440 1.00 20.18 ? 363 SER B OG 1 ATOM 6897 N N . LYS B 1 364 ? 6.040 -7.394 4.008 1.00 18.41 ? 364 LYS B N 1 ATOM 6898 C CA . LYS B 1 364 ? 6.584 -7.986 2.786 1.00 18.82 ? 364 LYS B CA 1 ATOM 6899 C C . LYS B 1 364 ? 7.613 -9.073 3.127 1.00 19.00 ? 364 LYS B C 1 ATOM 6900 O O . LYS B 1 364 ? 8.226 -9.661 2.232 1.00 18.85 ? 364 LYS B O 1 ATOM 6901 C CB . LYS B 1 364 ? 7.220 -6.894 1.910 1.00 18.77 ? 364 LYS B CB 1 ATOM 6902 C CG . LYS B 1 364 ? 6.205 -5.881 1.359 1.00 19.21 ? 364 LYS B CG 1 ATOM 6903 C CD . LYS B 1 364 ? 6.809 -4.952 0.299 1.00 21.05 ? 364 LYS B CD 1 ATOM 6904 C CE . LYS B 1 364 ? 6.046 -3.608 0.220 1.00 21.88 ? 364 LYS B CE 1 ATOM 6905 N NZ . LYS B 1 364 ? 6.174 -2.772 1.516 1.00 23.61 ? 364 LYS B NZ 1 ATOM 6906 N N . HIS B 1 365 ? 7.788 -9.320 4.428 1.00 19.43 ? 365 HIS B N 1 ATOM 6907 C CA . HIS B 1 365 ? 8.772 -10.298 4.945 1.00 19.79 ? 365 HIS B CA 1 ATOM 6908 C C . HIS B 1 365 ? 8.134 -11.292 5.904 1.00 18.92 ? 365 HIS B C 1 ATOM 6909 O O . HIS B 1 365 ? 8.285 -11.174 7.120 1.00 17.78 ? 365 HIS B O 1 ATOM 6910 C CB . HIS B 1 365 ? 9.940 -9.566 5.620 1.00 19.66 ? 365 HIS B CB 1 ATOM 6911 C CG . HIS B 1 365 ? 10.843 -8.891 4.645 1.00 22.16 ? 365 HIS B CG 1 ATOM 6912 N ND1 . HIS B 1 365 ? 10.746 -7.545 4.346 1.00 24.76 ? 365 HIS B ND1 1 ATOM 6913 C CD2 . HIS B 1 365 ? 11.826 -9.383 3.854 1.00 21.54 ? 365 HIS B CD2 1 ATOM 6914 C CE1 . HIS B 1 365 ? 11.652 -7.233 3.436 1.00 23.53 ? 365 HIS B CE1 1 ATOM 6915 N NE2 . HIS B 1 365 ? 12.317 -8.329 3.116 1.00 26.26 ? 365 HIS B NE2 1 ATOM 6916 N N . PRO B 1 366 ? 7.433 -12.296 5.366 1.00 19.53 ? 366 PRO B N 1 ATOM 6917 C CA . PRO B 1 366 ? 6.622 -13.119 6.298 1.00 20.40 ? 366 PRO B CA 1 ATOM 6918 C C . PRO B 1 366 ? 7.400 -13.932 7.363 1.00 20.68 ? 366 PRO B C 1 ATOM 6919 O O . PRO B 1 366 ? 6.857 -14.147 8.438 1.00 21.37 ? 366 PRO B O 1 ATOM 6920 C CB . PRO B 1 366 ? 5.804 -14.031 5.372 1.00 20.23 ? 366 PRO B CB 1 ATOM 6921 C CG . PRO B 1 366 ? 6.523 -14.002 4.045 1.00 21.27 ? 366 PRO B CG 1 ATOM 6922 C CD . PRO B 1 366 ? 7.311 -12.725 3.960 1.00 19.72 ? 366 PRO B CD 1 ATOM 6923 N N . ALA B 1 367 ? 8.629 -14.383 7.085 1.00 21.02 ? 367 ALA B N 1 ATOM 6924 C CA . ALA B 1 367 ? 9.438 -15.067 8.127 1.00 21.39 ? 367 ALA B CA 1 ATOM 6925 C C . ALA B 1 367 ? 9.849 -14.092 9.215 1.00 20.98 ? 367 ALA B C 1 ATOM 6926 O O . ALA B 1 367 ? 9.825 -14.430 10.398 1.00 21.31 ? 367 ALA B O 1 ATOM 6927 C CB . ALA B 1 367 ? 10.722 -15.739 7.537 1.00 20.93 ? 367 ALA B CB 1 ATOM 6928 N N . VAL B 1 368 ? 10.255 -12.886 8.810 1.00 20.21 ? 368 VAL B N 1 ATOM 6929 C CA . VAL B 1 368 ? 10.654 -11.862 9.764 1.00 19.41 ? 368 VAL B CA 1 ATOM 6930 C C . VAL B 1 368 ? 9.455 -11.461 10.628 1.00 20.15 ? 368 VAL B C 1 ATOM 6931 O O . VAL B 1 368 ? 9.579 -11.238 11.862 1.00 19.55 ? 368 VAL B O 1 ATOM 6932 C CB . VAL B 1 368 ? 11.245 -10.648 9.026 1.00 19.65 ? 368 VAL B CB 1 ATOM 6933 C CG1 . VAL B 1 368 ? 11.559 -9.502 10.002 1.00 17.29 ? 368 VAL B CG1 1 ATOM 6934 C CG2 . VAL B 1 368 ? 12.512 -11.098 8.236 1.00 18.83 ? 368 VAL B CG2 1 ATOM 6935 N N . ARG B 1 369 ? 8.309 -11.335 9.962 1.00 19.21 ? 369 ARG B N 1 ATOM 6936 C CA . ARG B 1 369 ? 7.054 -10.979 10.617 1.00 20.49 ? 369 ARG B CA 1 ATOM 6937 C C . ARG B 1 369 ? 6.674 -12.017 11.703 1.00 20.31 ? 369 ARG B C 1 ATOM 6938 O O . ARG B 1 369 ? 6.381 -11.650 12.842 1.00 19.55 ? 369 ARG B O 1 ATOM 6939 C CB . ARG B 1 369 ? 5.962 -10.779 9.554 1.00 20.45 ? 369 ARG B CB 1 ATOM 6940 C CG . ARG B 1 369 ? 4.516 -10.581 10.059 1.00 21.44 ? 369 ARG B CG 1 ATOM 6941 C CD . ARG B 1 369 ? 3.557 -10.842 8.888 1.00 26.12 ? 369 ARG B CD 1 ATOM 6942 N NE . ARG B 1 369 ? 2.149 -10.659 9.253 1.00 30.86 ? 369 ARG B NE 1 ATOM 6943 C CZ . ARG B 1 369 ? 1.166 -10.408 8.381 1.00 32.84 ? 369 ARG B CZ 1 ATOM 6944 N NH1 . ARG B 1 369 ? 1.421 -10.279 7.074 1.00 33.86 ? 369 ARG B NH1 1 ATOM 6945 N NH2 . ARG B 1 369 ? -0.082 -10.264 8.816 1.00 32.69 ? 369 ARG B NH2 1 ATOM 6946 N N . THR B 1 370 ? 6.734 -13.299 11.347 1.00 21.47 ? 370 THR B N 1 ATOM 6947 C CA . THR B 1 370 ? 6.514 -14.397 12.292 1.00 22.51 ? 370 THR B CA 1 ATOM 6948 C C . THR B 1 370 ? 7.494 -14.367 13.467 1.00 23.06 ? 370 THR B C 1 ATOM 6949 O O . THR B 1 370 ? 7.087 -14.550 14.616 1.00 22.95 ? 370 THR B O 1 ATOM 6950 C CB . THR B 1 370 ? 6.602 -15.760 11.572 1.00 23.53 ? 370 THR B CB 1 ATOM 6951 O OG1 . THR B 1 370 ? 5.610 -15.805 10.546 1.00 22.23 ? 370 THR B OG1 1 ATOM 6952 C CG2 . THR B 1 370 ? 6.403 -16.937 12.534 1.00 24.08 ? 370 THR B CG2 1 ATOM 6953 N N . TYR B 1 371 ? 8.769 -14.117 13.182 1.00 23.55 ? 371 TYR B N 1 ATOM 6954 C CA . TYR B 1 371 ? 9.804 -14.034 14.221 1.00 24.88 ? 371 TYR B CA 1 ATOM 6955 C C . TYR B 1 371 ? 9.492 -12.938 15.244 1.00 25.47 ? 371 TYR B C 1 ATOM 6956 O O . TYR B 1 371 ? 9.488 -13.171 16.460 1.00 25.38 ? 371 TYR B O 1 ATOM 6957 C CB . TYR B 1 371 ? 11.173 -13.789 13.580 1.00 25.10 ? 371 TYR B CB 1 ATOM 6958 C CG . TYR B 1 371 ? 12.341 -13.986 14.520 1.00 27.66 ? 371 TYR B CG 1 ATOM 6959 C CD1 . TYR B 1 371 ? 12.900 -12.905 15.196 1.00 30.09 ? 371 TYR B CD1 1 ATOM 6960 C CD2 . TYR B 1 371 ? 12.882 -15.260 14.749 1.00 30.16 ? 371 TYR B CD2 1 ATOM 6961 C CE1 . TYR B 1 371 ? 13.966 -13.073 16.069 1.00 31.36 ? 371 TYR B CE1 1 ATOM 6962 C CE2 . TYR B 1 371 ? 13.963 -15.437 15.630 1.00 30.28 ? 371 TYR B CE2 1 ATOM 6963 C CZ . TYR B 1 371 ? 14.484 -14.339 16.277 1.00 31.86 ? 371 TYR B CZ 1 ATOM 6964 O OH . TYR B 1 371 ? 15.535 -14.465 17.136 1.00 36.01 ? 371 TYR B OH 1 ATOM 6965 N N . SER B 1 372 ? 9.223 -11.730 14.753 1.00 25.77 ? 372 SER B N 1 ATOM 6966 C CA . SER B 1 372 ? 8.919 -10.628 15.642 1.00 26.13 ? 372 SER B CA 1 ATOM 6967 C C . SER B 1 372 ? 7.629 -10.876 16.449 1.00 26.44 ? 372 SER B C 1 ATOM 6968 O O . SER B 1 372 ? 7.516 -10.465 17.611 1.00 25.27 ? 372 SER B O 1 ATOM 6969 C CB . SER B 1 372 ? 8.868 -9.319 14.859 1.00 26.45 ? 372 SER B CB 1 ATOM 6970 O OG . SER B 1 372 ? 7.688 -9.215 14.097 1.00 27.84 ? 372 SER B OG 1 ATOM 6971 N N . TRP B 1 373 ? 6.669 -11.554 15.828 1.00 26.68 ? 373 TRP B N 1 ATOM 6972 C CA . TRP B 1 373 ? 5.452 -11.948 16.513 1.00 28.67 ? 373 TRP B CA 1 ATOM 6973 C C . TRP B 1 373 ? 5.762 -12.951 17.647 1.00 28.50 ? 373 TRP B C 1 ATOM 6974 O O . TRP B 1 373 ? 5.261 -12.792 18.762 1.00 27.65 ? 373 TRP B O 1 ATOM 6975 C CB . TRP B 1 373 ? 4.463 -12.536 15.508 1.00 29.62 ? 373 TRP B CB 1 ATOM 6976 C CG . TRP B 1 373 ? 3.151 -12.857 16.086 1.00 34.84 ? 373 TRP B CG 1 ATOM 6977 C CD1 . TRP B 1 373 ? 2.097 -12.010 16.258 1.00 38.42 ? 373 TRP B CD1 1 ATOM 6978 C CD2 . TRP B 1 373 ? 2.731 -14.132 16.580 1.00 39.46 ? 373 TRP B CD2 1 ATOM 6979 N NE1 . TRP B 1 373 ? 1.036 -12.682 16.826 1.00 41.98 ? 373 TRP B NE1 1 ATOM 6980 C CE2 . TRP B 1 373 ? 1.400 -13.987 17.034 1.00 40.44 ? 373 TRP B CE2 1 ATOM 6981 C CE3 . TRP B 1 373 ? 3.348 -15.384 16.674 1.00 40.35 ? 373 TRP B CE3 1 ATOM 6982 C CZ2 . TRP B 1 373 ? 0.674 -15.045 17.576 1.00 42.22 ? 373 TRP B CZ2 1 ATOM 6983 C CZ3 . TRP B 1 373 ? 2.627 -16.440 17.211 1.00 44.04 ? 373 TRP B CZ3 1 ATOM 6984 C CH2 . TRP B 1 373 ? 1.301 -16.262 17.662 1.00 43.64 ? 373 TRP B CH2 1 ATOM 6985 N N . LYS B 1 374 ? 6.613 -13.942 17.365 1.00 28.67 ? 374 LYS B N 1 ATOM 6986 C CA . LYS B 1 374 ? 6.994 -14.959 18.376 1.00 29.77 ? 374 LYS B CA 1 ATOM 6987 C C . LYS B 1 374 ? 7.818 -14.417 19.543 1.00 29.24 ? 374 LYS B C 1 ATOM 6988 O O . LYS B 1 374 ? 7.613 -14.830 20.672 1.00 29.32 ? 374 LYS B O 1 ATOM 6989 C CB . LYS B 1 374 ? 7.714 -16.160 17.752 1.00 30.01 ? 374 LYS B CB 1 ATOM 6990 C CG . LYS B 1 374 ? 6.792 -17.146 17.085 1.00 32.44 ? 374 LYS B CG 1 ATOM 6991 C CD . LYS B 1 374 ? 7.599 -18.272 16.458 1.00 35.59 ? 374 LYS B CD 1 ATOM 6992 C CE . LYS B 1 374 ? 6.699 -19.324 15.829 1.00 37.26 ? 374 LYS B CE 1 ATOM 6993 N NZ . LYS B 1 374 ? 7.456 -20.068 14.756 1.00 38.48 ? 374 LYS B NZ 1 ATOM 6994 N N . LYS B 1 375 ? 8.734 -13.492 19.280 1.00 28.61 ? 375 LYS B N 1 ATOM 6995 C CA . LYS B 1 375 ? 9.441 -12.826 20.363 1.00 28.12 ? 375 LYS B CA 1 ATOM 6996 C C . LYS B 1 375 ? 8.678 -11.621 20.963 1.00 26.83 ? 375 LYS B C 1 ATOM 6997 O O . LYS B 1 375 ? 9.259 -10.866 21.735 1.00 26.44 ? 375 LYS B O 1 ATOM 6998 C CB . LYS B 1 375 ? 10.837 -12.370 19.913 1.00 28.57 ? 375 LYS B CB 1 ATOM 6999 C CG . LYS B 1 375 ? 11.694 -13.436 19.252 1.00 32.24 ? 375 LYS B CG 1 ATOM 7000 C CD . LYS B 1 375 ? 12.288 -14.404 20.261 1.00 37.06 ? 375 LYS B CD 1 ATOM 7001 C CE . LYS B 1 375 ? 13.113 -15.479 19.545 1.00 42.24 ? 375 LYS B CE 1 ATOM 7002 N NZ . LYS B 1 375 ? 13.618 -16.578 20.462 1.00 44.40 ? 375 LYS B NZ 1 ATOM 7003 N N . ASP B 1 376 ? 7.414 -11.429 20.585 1.00 24.79 ? 376 ASP B N 1 ATOM 7004 C CA . ASP B 1 376 ? 6.599 -10.283 21.036 1.00 23.70 ? 376 ASP B CA 1 ATOM 7005 C C . ASP B 1 376 ? 7.318 -8.928 20.909 1.00 22.25 ? 376 ASP B C 1 ATOM 7006 O O . ASP B 1 376 ? 7.317 -8.122 21.849 1.00 21.59 ? 376 ASP B O 1 ATOM 7007 C CB . ASP B 1 376 ? 6.061 -10.511 22.485 1.00 23.42 ? 376 ASP B CB 1 ATOM 7008 C CG . ASP B 1 376 ? 4.830 -9.676 22.804 1.00 25.30 ? 376 ASP B CG 1 ATOM 7009 O OD1 . ASP B 1 376 ? 4.160 -9.173 21.873 1.00 24.35 ? 376 ASP B OD1 1 ATOM 7010 O OD2 . ASP B 1 376 ? 4.530 -9.494 24.007 1.00 29.03 ? 376 ASP B OD2 1 ATOM 7011 N N . ILE B 1 377 ? 7.923 -8.674 19.743 1.00 21.12 ? 377 ILE B N 1 ATOM 7012 C CA . ILE B 1 377 ? 8.593 -7.396 19.480 1.00 19.95 ? 377 ILE B CA 1 ATOM 7013 C C . ILE B 1 377 ? 7.699 -6.492 18.603 1.00 19.10 ? 377 ILE B C 1 ATOM 7014 O O . ILE B 1 377 ? 7.444 -6.820 17.437 1.00 19.84 ? 377 ILE B O 1 ATOM 7015 C CB . ILE B 1 377 ? 9.976 -7.592 18.760 1.00 20.31 ? 377 ILE B CB 1 ATOM 7016 C CG1 . ILE B 1 377 ? 10.862 -8.586 19.524 1.00 18.94 ? 377 ILE B CG1 1 ATOM 7017 C CG2 . ILE B 1 377 ? 10.668 -6.218 18.507 1.00 19.02 ? 377 ILE B CG2 1 ATOM 7018 C CD1 . ILE B 1 377 ? 11.228 -8.142 20.974 1.00 18.48 ? 377 ILE B CD1 1 ATOM 7019 N N . PRO B 1 378 ? 7.246 -5.350 19.146 1.00 18.08 ? 378 PRO B N 1 ATOM 7020 C CA . PRO B 1 378 ? 6.257 -4.537 18.422 1.00 17.37 ? 378 PRO B CA 1 ATOM 7021 C C . PRO B 1 378 ? 6.904 -3.564 17.439 1.00 17.10 ? 378 PRO B C 1 ATOM 7022 O O . PRO B 1 378 ? 8.072 -3.164 17.599 1.00 17.51 ? 378 PRO B O 1 ATOM 7023 C CB . PRO B 1 378 ? 5.586 -3.723 19.541 1.00 17.24 ? 378 PRO B CB 1 ATOM 7024 C CG . PRO B 1 378 ? 6.786 -3.479 20.539 1.00 16.70 ? 378 PRO B CG 1 ATOM 7025 C CD . PRO B 1 378 ? 7.611 -4.759 20.457 1.00 17.21 ? 378 PRO B CD 1 ATOM 7026 N N . ILE B 1 379 ? 6.126 -3.173 16.439 1.00 16.37 ? 379 ILE B N 1 ATOM 7027 C CA . ILE B 1 379 ? 6.460 -2.015 15.612 1.00 15.05 ? 379 ILE B CA 1 ATOM 7028 C C . ILE B 1 379 ? 5.781 -0.752 16.139 1.00 15.46 ? 379 ILE B C 1 ATOM 7029 O O . ILE B 1 379 ? 4.682 -0.817 16.700 1.00 15.57 ? 379 ILE B O 1 ATOM 7030 C CB . ILE B 1 379 ? 6.056 -2.206 14.135 1.00 14.96 ? 379 ILE B CB 1 ATOM 7031 C CG1 . ILE B 1 379 ? 4.542 -2.542 13.986 1.00 12.37 ? 379 ILE B CG1 1 ATOM 7032 C CG2 . ILE B 1 379 ? 6.995 -3.226 13.471 1.00 13.37 ? 379 ILE B CG2 1 ATOM 7033 C CD1 . ILE B 1 379 ? 4.062 -2.459 12.508 1.00 15.02 ? 379 ILE B CD1 1 ATOM 7034 N N . GLU B 1 380 ? 6.443 0.384 15.926 1.00 14.80 ? 380 GLU B N 1 ATOM 7035 C CA . GLU B 1 380 ? 5.961 1.689 16.314 1.00 15.02 ? 380 GLU B CA 1 ATOM 7036 C C . GLU B 1 380 ? 5.493 2.367 15.038 1.00 16.06 ? 380 GLU B C 1 ATOM 7037 O O . GLU B 1 380 ? 6.295 2.712 14.161 1.00 15.35 ? 380 GLU B O 1 ATOM 7038 C CB . GLU B 1 380 ? 7.084 2.519 16.945 1.00 15.36 ? 380 GLU B CB 1 ATOM 7039 C CG . GLU B 1 380 ? 7.760 1.909 18.205 1.00 16.28 ? 380 GLU B CG 1 ATOM 7040 C CD . GLU B 1 380 ? 9.145 2.543 18.485 1.00 19.54 ? 380 GLU B CD 1 ATOM 7041 O OE1 . GLU B 1 380 ? 9.892 2.843 17.510 1.00 19.20 ? 380 GLU B OE1 1 ATOM 7042 O OE2 . GLU B 1 380 ? 9.469 2.786 19.666 1.00 19.68 ? 380 GLU B OE2 1 ATOM 7043 N N . VAL B 1 381 ? 4.185 2.559 14.912 1.00 16.64 ? 381 VAL B N 1 ATOM 7044 C CA . VAL B 1 381 ? 3.678 3.078 13.655 1.00 16.71 ? 381 VAL B CA 1 ATOM 7045 C C . VAL B 1 381 ? 3.301 4.547 13.731 1.00 16.62 ? 381 VAL B C 1 ATOM 7046 O O . VAL B 1 381 ? 2.611 4.987 14.667 1.00 14.90 ? 381 VAL B O 1 ATOM 7047 C CB . VAL B 1 381 ? 2.641 2.103 12.951 1.00 18.44 ? 381 VAL B CB 1 ATOM 7048 C CG1 . VAL B 1 381 ? 2.224 0.921 13.832 1.00 19.34 ? 381 VAL B CG1 1 ATOM 7049 C CG2 . VAL B 1 381 ? 1.498 2.808 12.223 1.00 16.31 ? 381 VAL B CG2 1 ATOM 7050 N N . CYS B 1 382 ? 3.800 5.295 12.742 1.00 16.00 ? 382 CYS B N 1 ATOM 7051 C CA . CYS B 1 382 ? 3.674 6.762 12.710 1.00 16.35 ? 382 CYS B CA 1 ATOM 7052 C C . CYS B 1 382 ? 3.073 7.159 11.344 1.00 15.44 ? 382 CYS B C 1 ATOM 7053 O O . CYS B 1 382 ? 3.804 7.495 10.393 1.00 13.46 ? 382 CYS B O 1 ATOM 7054 C CB . CYS B 1 382 ? 5.052 7.412 12.961 1.00 17.24 ? 382 CYS B CB 1 ATOM 7055 S SG . CYS B 1 382 ? 5.805 6.985 14.597 1.00 22.90 ? 382 CYS B SG 1 ATOM 7056 N N . PRO B 1 383 ? 1.731 7.085 11.224 1.00 14.85 ? 383 PRO B N 1 ATOM 7057 C CA . PRO B 1 383 ? 1.161 7.145 9.881 1.00 14.36 ? 383 PRO B CA 1 ATOM 7058 C C . PRO B 1 383 ? 1.342 8.496 9.165 1.00 14.50 ? 383 PRO B C 1 ATOM 7059 O O . PRO B 1 383 ? 1.579 8.511 7.951 1.00 13.26 ? 383 PRO B O 1 ATOM 7060 C CB . PRO B 1 383 ? -0.345 6.831 10.112 1.00 15.00 ? 383 PRO B CB 1 ATOM 7061 C CG . PRO B 1 383 ? -0.590 7.185 11.580 1.00 15.16 ? 383 PRO B CG 1 ATOM 7062 C CD . PRO B 1 383 ? 0.701 6.826 12.260 1.00 15.15 ? 383 PRO B CD 1 ATOM 7063 N N . ILE B 1 384 ? 1.240 9.614 9.883 1.00 13.83 ? 384 ILE B N 1 ATOM 7064 C CA . ILE B 1 384 ? 1.341 10.942 9.225 1.00 14.14 ? 384 ILE B CA 1 ATOM 7065 C C . ILE B 1 384 ? 2.758 11.182 8.702 1.00 13.85 ? 384 ILE B C 1 ATOM 7066 O O . ILE B 1 384 ? 2.956 11.654 7.574 1.00 14.25 ? 384 ILE B O 1 ATOM 7067 C CB . ILE B 1 384 ? 0.864 12.096 10.130 1.00 13.65 ? 384 ILE B CB 1 ATOM 7068 C CG1 . ILE B 1 384 ? -0.654 11.957 10.358 1.00 14.47 ? 384 ILE B CG1 1 ATOM 7069 C CG2 . ILE B 1 384 ? 1.199 13.477 9.487 1.00 13.52 ? 384 ILE B CG2 1 ATOM 7070 C CD1 . ILE B 1 384 ? -1.173 12.801 11.546 1.00 13.25 ? 384 ILE B CD1 1 ATOM 7071 N N . SER B 1 385 ? 3.732 10.788 9.504 1.00 13.43 ? 385 SER B N 1 ATOM 7072 C CA . SER B 1 385 ? 5.126 10.797 9.066 1.00 14.76 ? 385 SER B CA 1 ATOM 7073 C C . SER B 1 385 ? 5.300 10.071 7.712 1.00 14.08 ? 385 SER B C 1 ATOM 7074 O O . SER B 1 385 ? 5.851 10.624 6.749 1.00 13.53 ? 385 SER B O 1 ATOM 7075 C CB . SER B 1 385 ? 6.011 10.140 10.153 1.00 13.79 ? 385 SER B CB 1 ATOM 7076 O OG . SER B 1 385 ? 7.356 10.215 9.733 1.00 17.92 ? 385 SER B OG 1 ATOM 7077 N N . ASN B 1 386 ? 4.834 8.821 7.651 1.00 14.57 ? 386 ASN B N 1 ATOM 7078 C CA . ASN B 1 386 ? 4.911 8.016 6.427 1.00 14.38 ? 386 ASN B CA 1 ATOM 7079 C C . ASN B 1 386 ? 4.220 8.677 5.198 1.00 14.82 ? 386 ASN B C 1 ATOM 7080 O O . ASN B 1 386 ? 4.692 8.526 4.058 1.00 13.64 ? 386 ASN B O 1 ATOM 7081 C CB . ASN B 1 386 ? 4.325 6.606 6.622 1.00 15.21 ? 386 ASN B CB 1 ATOM 7082 C CG . ASN B 1 386 ? 5.001 5.791 7.753 1.00 15.37 ? 386 ASN B CG 1 ATOM 7083 O OD1 . ASN B 1 386 ? 4.383 4.850 8.276 1.00 17.40 ? 386 ASN B OD1 1 ATOM 7084 N ND2 . ASN B 1 386 ? 6.234 6.157 8.152 1.00 13.97 ? 386 ASN B ND2 1 ATOM 7085 N N . GLN B 1 387 ? 3.101 9.377 5.420 1.00 13.38 ? 387 GLN B N 1 ATOM 7086 C CA . GLN B 1 387 ? 2.462 10.088 4.323 1.00 14.80 ? 387 GLN B CA 1 ATOM 7087 C C . GLN B 1 387 ? 3.243 11.338 3.904 1.00 14.36 ? 387 GLN B C 1 ATOM 7088 O O . GLN B 1 387 ? 3.534 11.527 2.715 1.00 15.00 ? 387 GLN B O 1 ATOM 7089 C CB . GLN B 1 387 ? 1.004 10.437 4.660 1.00 14.77 ? 387 GLN B CB 1 ATOM 7090 C CG . GLN B 1 387 ? 0.208 10.983 3.495 1.00 15.64 ? 387 GLN B CG 1 ATOM 7091 C CD . GLN B 1 387 ? -1.248 11.311 3.884 1.00 13.20 ? 387 GLN B CD 1 ATOM 7092 O OE1 . GLN B 1 387 ? -1.501 12.138 4.758 1.00 14.72 ? 387 GLN B OE1 1 ATOM 7093 N NE2 . GLN B 1 387 ? -2.191 10.658 3.226 1.00 13.00 ? 387 GLN B NE2 1 ATOM 7094 N N . VAL B 1 388 ? 3.558 12.197 4.871 1.00 13.95 ? 388 VAL B N 1 ATOM 7095 C CA . VAL B 1 388 ? 4.279 13.448 4.604 1.00 15.03 ? 388 VAL B CA 1 ATOM 7096 C C . VAL B 1 388 ? 5.651 13.222 3.948 1.00 15.20 ? 388 VAL B C 1 ATOM 7097 O O . VAL B 1 388 ? 6.040 13.977 3.029 1.00 15.43 ? 388 VAL B O 1 ATOM 7098 C CB . VAL B 1 388 ? 4.418 14.312 5.897 1.00 15.79 ? 388 VAL B CB 1 ATOM 7099 C CG1 . VAL B 1 388 ? 5.285 15.544 5.666 1.00 17.53 ? 388 VAL B CG1 1 ATOM 7100 C CG2 . VAL B 1 388 ? 3.060 14.733 6.396 1.00 16.77 ? 388 VAL B CG2 1 ATOM 7101 N N . LEU B 1 389 ? 6.358 12.165 4.373 1.00 14.65 ? 389 LEU B N 1 ATOM 7102 C CA . LEU B 1 389 ? 7.678 11.836 3.792 1.00 14.97 ? 389 LEU B CA 1 ATOM 7103 C C . LEU B 1 389 ? 7.578 10.899 2.584 1.00 15.81 ? 389 LEU B C 1 ATOM 7104 O O . LEU B 1 389 ? 8.579 10.327 2.125 1.00 16.79 ? 389 LEU B O 1 ATOM 7105 C CB . LEU B 1 389 ? 8.623 11.297 4.871 1.00 14.62 ? 389 LEU B CB 1 ATOM 7106 C CG . LEU B 1 389 ? 8.728 12.252 6.091 1.00 14.85 ? 389 LEU B CG 1 ATOM 7107 C CD1 . LEU B 1 389 ? 9.535 11.638 7.278 1.00 15.02 ? 389 LEU B CD1 1 ATOM 7108 C CD2 . LEU B 1 389 ? 9.296 13.624 5.704 1.00 16.96 ? 389 LEU B CD2 1 ATOM 7109 N N . LYS B 1 390 ? 6.359 10.760 2.073 1.00 16.60 ? 390 LYS B N 1 ATOM 7110 C CA . LYS B 1 390 ? 6.084 10.195 0.740 1.00 16.53 ? 390 LYS B CA 1 ATOM 7111 C C . LYS B 1 390 ? 6.311 8.679 0.593 1.00 15.93 ? 390 LYS B C 1 ATOM 7112 O O . LYS B 1 390 ? 6.554 8.193 -0.517 1.00 16.26 ? 390 LYS B O 1 ATOM 7113 C CB . LYS B 1 390 ? 6.841 10.959 -0.378 1.00 17.19 ? 390 LYS B CB 1 ATOM 7114 C CG . LYS B 1 390 ? 6.562 12.489 -0.437 1.00 18.81 ? 390 LYS B CG 1 ATOM 7115 C CD . LYS B 1 390 ? 7.536 13.225 -1.385 1.00 20.78 ? 390 LYS B CD 1 ATOM 7116 C CE . LYS B 1 390 ? 7.192 12.984 -2.886 1.00 18.14 ? 390 LYS B CE 1 ATOM 7117 N NZ . LYS B 1 390 ? 5.763 13.387 -3.112 1.00 21.52 ? 390 LYS B NZ 1 ATOM 7118 N N . LEU B 1 391 ? 6.205 7.935 1.689 1.00 14.35 ? 391 LEU B N 1 ATOM 7119 C CA . LEU B 1 391 ? 6.249 6.470 1.609 1.00 14.42 ? 391 LEU B CA 1 ATOM 7120 C C . LEU B 1 391 ? 4.946 5.871 1.054 1.00 14.13 ? 391 LEU B C 1 ATOM 7121 O O . LEU B 1 391 ? 4.938 4.779 0.453 1.00 14.15 ? 391 LEU B O 1 ATOM 7122 C CB . LEU B 1 391 ? 6.543 5.892 2.991 1.00 13.60 ? 391 LEU B CB 1 ATOM 7123 C CG . LEU B 1 391 ? 7.990 5.517 3.393 1.00 16.93 ? 391 LEU B CG 1 ATOM 7124 C CD1 . LEU B 1 391 ? 9.137 5.971 2.498 1.00 16.17 ? 391 LEU B CD1 1 ATOM 7125 C CD2 . LEU B 1 391 ? 8.259 5.754 4.848 1.00 15.17 ? 391 LEU B CD2 1 ATOM 7126 N N . VAL B 1 392 ? 3.836 6.568 1.265 1.00 14.02 ? 392 VAL B N 1 ATOM 7127 C CA . VAL B 1 392 ? 2.553 6.110 0.741 1.00 14.23 ? 392 VAL B CA 1 ATOM 7128 C C . VAL B 1 392 ? 1.623 7.314 0.599 1.00 15.57 ? 392 VAL B C 1 ATOM 7129 O O . VAL B 1 392 ? 1.653 8.243 1.441 1.00 15.51 ? 392 VAL B O 1 ATOM 7130 C CB . VAL B 1 392 ? 1.923 4.986 1.602 1.00 14.45 ? 392 VAL B CB 1 ATOM 7131 C CG1 . VAL B 1 392 ? 1.684 5.457 3.051 1.00 16.52 ? 392 VAL B CG1 1 ATOM 7132 C CG2 . VAL B 1 392 ? 0.653 4.409 0.921 1.00 13.35 ? 392 VAL B CG2 1 ATOM 7133 N N . SER B 1 393 ? 0.835 7.335 -0.477 1.00 15.09 ? 393 SER B N 1 ATOM 7134 C CA . SER B 1 393 ? 0.052 8.542 -0.758 1.00 17.82 ? 393 SER B CA 1 ATOM 7135 C C . SER B 1 393 ? -1.331 8.533 -0.033 1.00 16.73 ? 393 SER B C 1 ATOM 7136 O O . SER B 1 393 ? -1.713 9.484 0.634 1.00 17.68 ? 393 SER B O 1 ATOM 7137 C CB . SER B 1 393 ? -0.059 8.725 -2.283 1.00 17.19 ? 393 SER B CB 1 ATOM 7138 O OG . SER B 1 393 ? -0.926 9.810 -2.552 1.00 24.05 ? 393 SER B OG 1 ATOM 7139 N N . ASP B 1 394 ? -2.040 7.423 -0.163 1.00 16.70 ? 394 ASP B N 1 ATOM 7140 C CA . ASP B 1 394 ? -3.366 7.176 0.432 1.00 15.62 ? 394 ASP B CA 1 ATOM 7141 C C . ASP B 1 394 ? -3.154 6.236 1.602 1.00 14.90 ? 394 ASP B C 1 ATOM 7142 O O . ASP B 1 394 ? -2.689 5.112 1.403 1.00 15.63 ? 394 ASP B O 1 ATOM 7143 C CB . ASP B 1 394 ? -4.210 6.482 -0.655 1.00 15.82 ? 394 ASP B CB 1 ATOM 7144 C CG . ASP B 1 394 ? -5.657 6.206 -0.250 1.00 16.71 ? 394 ASP B CG 1 ATOM 7145 O OD1 . ASP B 1 394 ? -6.028 6.220 0.963 1.00 19.44 ? 394 ASP B OD1 1 ATOM 7146 O OD2 . ASP B 1 394 ? -6.445 5.952 -1.198 1.00 21.60 ? 394 ASP B OD2 1 ATOM 7147 N N . LEU B 1 395 ? -3.471 6.666 2.822 1.00 14.11 ? 395 LEU B N 1 ATOM 7148 C CA . LEU B 1 395 ? -3.226 5.829 4.006 1.00 13.64 ? 395 LEU B CA 1 ATOM 7149 C C . LEU B 1 395 ? -4.093 4.574 4.076 1.00 13.98 ? 395 LEU B C 1 ATOM 7150 O O . LEU B 1 395 ? -3.760 3.650 4.843 1.00 14.00 ? 395 LEU B O 1 ATOM 7151 C CB . LEU B 1 395 ? -3.325 6.629 5.331 1.00 13.19 ? 395 LEU B CB 1 ATOM 7152 C CG . LEU B 1 395 ? -2.154 7.604 5.557 1.00 13.44 ? 395 LEU B CG 1 ATOM 7153 C CD1 . LEU B 1 395 ? -2.474 8.723 6.549 1.00 12.00 ? 395 LEU B CD1 1 ATOM 7154 C CD2 . LEU B 1 395 ? -0.886 6.840 5.998 1.00 13.18 ? 395 LEU B CD2 1 ATOM 7155 N N . ARG B 1 396 ? -5.168 4.506 3.264 1.00 13.39 ? 396 ARG B N 1 ATOM 7156 C CA . ARG B 1 396 ? -5.917 3.252 3.114 1.00 14.25 ? 396 ARG B CA 1 ATOM 7157 C C . ARG B 1 396 ? -5.009 2.142 2.559 1.00 14.93 ? 396 ARG B C 1 ATOM 7158 O O . ARG B 1 396 ? -5.301 0.955 2.775 1.00 15.39 ? 396 ARG B O 1 ATOM 7159 C CB . ARG B 1 396 ? -7.158 3.416 2.195 1.00 14.95 ? 396 ARG B CB 1 ATOM 7160 C CG . ARG B 1 396 ? -8.289 4.260 2.791 1.00 14.82 ? 396 ARG B CG 1 ATOM 7161 C CD . ARG B 1 396 ? -9.422 4.441 1.790 1.00 14.99 ? 396 ARG B CD 1 ATOM 7162 N NE . ARG B 1 396 ? -8.979 5.156 0.580 1.00 16.24 ? 396 ARG B NE 1 ATOM 7163 C CZ . ARG B 1 396 ? -9.786 5.509 -0.426 1.00 16.59 ? 396 ARG B CZ 1 ATOM 7164 N NH1 . ARG B 1 396 ? -11.092 5.250 -0.373 1.00 17.53 ? 396 ARG B NH1 1 ATOM 7165 N NH2 . ARG B 1 396 ? -9.296 6.128 -1.484 1.00 16.53 ? 396 ARG B NH2 1 ATOM 7166 N N . ASN B 1 397 ? -3.935 2.519 1.840 1.00 14.22 ? 397 ASN B N 1 ATOM 7167 C CA . ASN B 1 397 ? -2.960 1.545 1.301 1.00 14.42 ? 397 ASN B CA 1 ATOM 7168 C C . ASN B 1 397 ? -1.783 1.290 2.233 1.00 13.62 ? 397 ASN B C 1 ATOM 7169 O O . ASN B 1 397 ? -0.821 0.640 1.825 1.00 13.39 ? 397 ASN B O 1 ATOM 7170 C CB . ASN B 1 397 ? -2.386 2.015 -0.077 1.00 15.03 ? 397 ASN B CB 1 ATOM 7171 C CG . ASN B 1 397 ? -3.429 1.965 -1.218 1.00 17.51 ? 397 ASN B CG 1 ATOM 7172 O OD1 . ASN B 1 397 ? -3.508 2.877 -2.088 1.00 17.17 ? 397 ASN B OD1 1 ATOM 7173 N ND2 . ASN B 1 397 ? -4.222 0.926 -1.221 1.00 15.29 ? 397 ASN B ND2 1 ATOM 7174 N N . HIS B 1 398 ? -1.798 1.844 3.448 1.00 12.15 ? 398 HIS B N 1 ATOM 7175 C CA . HIS B 1 398 ? -0.657 1.682 4.357 1.00 12.26 ? 398 HIS B CA 1 ATOM 7176 C C . HIS B 1 398 ? -0.477 0.174 4.651 1.00 11.69 ? 398 HIS B C 1 ATOM 7177 O O . HIS B 1 398 ? -1.471 -0.501 4.929 1.00 11.00 ? 398 HIS B O 1 ATOM 7178 C CB . HIS B 1 398 ? -0.887 2.470 5.656 1.00 11.83 ? 398 HIS B CB 1 ATOM 7179 C CG . HIS B 1 398 ? 0.355 2.688 6.460 1.00 11.23 ? 398 HIS B CG 1 ATOM 7180 N ND1 . HIS B 1 398 ? 1.004 1.661 7.129 1.00 13.07 ? 398 HIS B ND1 1 ATOM 7181 C CD2 . HIS B 1 398 ? 1.064 3.810 6.717 1.00 11.40 ? 398 HIS B CD2 1 ATOM 7182 C CE1 . HIS B 1 398 ? 2.067 2.143 7.746 1.00 10.14 ? 398 HIS B CE1 1 ATOM 7183 N NE2 . HIS B 1 398 ? 2.131 3.445 7.510 1.00 12.97 ? 398 HIS B NE2 1 ATOM 7184 N N . PRO B 1 399 ? 0.769 -0.356 4.563 1.00 12.17 ? 399 PRO B N 1 ATOM 7185 C CA . PRO B 1 399 ? 0.979 -1.822 4.789 1.00 12.24 ? 399 PRO B CA 1 ATOM 7186 C C . PRO B 1 399 ? 0.618 -2.307 6.188 1.00 13.15 ? 399 PRO B C 1 ATOM 7187 O O . PRO B 1 399 ? 0.405 -3.525 6.388 1.00 13.58 ? 399 PRO B O 1 ATOM 7188 C CB . PRO B 1 399 ? 2.502 -1.993 4.589 1.00 11.69 ? 399 PRO B CB 1 ATOM 7189 C CG . PRO B 1 399 ? 3.083 -0.597 4.939 1.00 11.57 ? 399 PRO B CG 1 ATOM 7190 C CD . PRO B 1 399 ? 2.055 0.315 4.268 1.00 10.24 ? 399 PRO B CD 1 ATOM 7191 N N . VAL B 1 400 ? 0.548 -1.401 7.160 1.00 12.98 ? 400 VAL B N 1 ATOM 7192 C CA . VAL B 1 400 ? 0.130 -1.815 8.515 1.00 13.69 ? 400 VAL B CA 1 ATOM 7193 C C . VAL B 1 400 ? -1.327 -2.312 8.577 1.00 13.93 ? 400 VAL B C 1 ATOM 7194 O O . VAL B 1 400 ? -1.685 -3.090 9.466 1.00 13.52 ? 400 VAL B O 1 ATOM 7195 C CB . VAL B 1 400 ? 0.506 -0.764 9.601 1.00 14.37 ? 400 VAL B CB 1 ATOM 7196 C CG1 . VAL B 1 400 ? -0.203 -1.043 10.953 1.00 15.30 ? 400 VAL B CG1 1 ATOM 7197 C CG2 . VAL B 1 400 ? 2.018 -0.777 9.790 1.00 13.35 ? 400 VAL B CG2 1 ATOM 7198 N N . ALA B 1 401 ? -2.133 -1.954 7.576 1.00 13.63 ? 401 ALA B N 1 ATOM 7199 C CA . ALA B 1 401 ? -3.488 -2.503 7.495 1.00 14.55 ? 401 ALA B CA 1 ATOM 7200 C C . ALA B 1 401 ? -3.486 -4.035 7.588 1.00 15.25 ? 401 ALA B C 1 ATOM 7201 O O . ALA B 1 401 ? -4.243 -4.606 8.383 1.00 14.94 ? 401 ALA B O 1 ATOM 7202 C CB . ALA B 1 401 ? -4.210 -2.037 6.216 1.00 13.17 ? 401 ALA B CB 1 ATOM 7203 N N . THR B 1 402 ? -2.650 -4.697 6.779 1.00 16.20 ? 402 THR B N 1 ATOM 7204 C CA . THR B 1 402 ? -2.523 -6.169 6.852 1.00 17.61 ? 402 THR B CA 1 ATOM 7205 C C . THR B 1 402 ? -2.124 -6.680 8.237 1.00 17.14 ? 402 THR B C 1 ATOM 7206 O O . THR B 1 402 ? -2.627 -7.732 8.705 1.00 17.47 ? 402 THR B O 1 ATOM 7207 C CB . THR B 1 402 ? -1.524 -6.729 5.801 1.00 17.93 ? 402 THR B CB 1 ATOM 7208 O OG1 . THR B 1 402 ? -1.960 -6.321 4.498 1.00 21.61 ? 402 THR B OG1 1 ATOM 7209 C CG2 . THR B 1 402 ? -1.611 -8.198 5.813 1.00 21.44 ? 402 THR B CG2 1 ATOM 7210 N N . LEU B 1 403 ? -1.232 -5.944 8.894 1.00 16.48 ? 403 LEU B N 1 ATOM 7211 C CA . LEU B 1 403 ? -0.763 -6.306 10.239 1.00 16.80 ? 403 LEU B CA 1 ATOM 7212 C C . LEU B 1 403 ? -1.847 -6.121 11.307 1.00 16.40 ? 403 LEU B C 1 ATOM 7213 O O . LEU B 1 403 ? -1.961 -6.939 12.235 1.00 15.55 ? 403 LEU B O 1 ATOM 7214 C CB . LEU B 1 403 ? 0.464 -5.485 10.618 1.00 16.80 ? 403 LEU B CB 1 ATOM 7215 C CG . LEU B 1 403 ? 1.886 -5.947 10.256 1.00 20.37 ? 403 LEU B CG 1 ATOM 7216 C CD1 . LEU B 1 403 ? 1.996 -7.072 9.221 1.00 15.86 ? 403 LEU B CD1 1 ATOM 7217 C CD2 . LEU B 1 403 ? 2.751 -4.743 9.916 1.00 19.42 ? 403 LEU B CD2 1 ATOM 7218 N N . MET B 1 404 ? -2.616 -5.030 11.202 1.00 15.62 ? 404 MET B N 1 ATOM 7219 C CA . MET B 1 404 ? -3.775 -4.835 12.088 1.00 16.14 ? 404 MET B CA 1 ATOM 7220 C C . MET B 1 404 ? -4.813 -5.980 11.977 1.00 16.58 ? 404 MET B C 1 ATOM 7221 O O . MET B 1 404 ? -5.387 -6.406 12.994 1.00 17.23 ? 404 MET B O 1 ATOM 7222 C CB . MET B 1 404 ? -4.429 -3.481 11.820 1.00 16.74 ? 404 MET B CB 1 ATOM 7223 C CG . MET B 1 404 ? -3.648 -2.282 12.362 1.00 17.29 ? 404 MET B CG 1 ATOM 7224 S SD . MET B 1 404 ? -4.541 -0.718 12.007 1.00 19.96 ? 404 MET B SD 1 ATOM 7225 C CE . MET B 1 404 ? -5.772 -0.766 13.321 1.00 18.22 ? 404 MET B CE 1 ATOM 7226 N N . ALA B 1 405 ? -5.015 -6.499 10.763 1.00 15.81 ? 405 ALA B N 1 ATOM 7227 C CA . ALA B 1 405 ? -5.982 -7.562 10.524 1.00 16.96 ? 405 ALA B CA 1 ATOM 7228 C C . ALA B 1 405 ? -5.602 -8.900 11.184 1.00 18.17 ? 405 ALA B C 1 ATOM 7229 O O . ALA B 1 405 ? -6.471 -9.733 11.412 1.00 17.96 ? 405 ALA B O 1 ATOM 7230 C CB . ALA B 1 405 ? -6.207 -7.754 9.048 1.00 16.94 ? 405 ALA B CB 1 ATOM 7231 N N . THR B 1 406 ? -4.324 -9.084 11.524 1.00 18.92 ? 406 THR B N 1 ATOM 7232 C CA . THR B 1 406 ? -3.911 -10.299 12.221 1.00 20.54 ? 406 THR B CA 1 ATOM 7233 C C . THR B 1 406 ? -3.507 -9.994 13.648 1.00 20.58 ? 406 THR B C 1 ATOM 7234 O O . THR B 1 406 ? -2.938 -10.854 14.327 1.00 21.40 ? 406 THR B O 1 ATOM 7235 C CB . THR B 1 406 ? -2.742 -11.031 11.510 1.00 21.17 ? 406 THR B CB 1 ATOM 7236 O OG1 . THR B 1 406 ? -1.593 -10.170 11.445 1.00 21.87 ? 406 THR B OG1 1 ATOM 7237 C CG2 . THR B 1 406 ? -3.146 -11.426 10.104 1.00 22.19 ? 406 THR B CG2 1 ATOM 7238 N N . GLY B 1 407 ? -3.795 -8.777 14.110 1.00 20.30 ? 407 GLY B N 1 ATOM 7239 C CA . GLY B 1 407 ? -3.482 -8.393 15.492 1.00 20.02 ? 407 GLY B CA 1 ATOM 7240 C C . GLY B 1 407 ? -2.010 -8.388 15.878 1.00 20.56 ? 407 GLY B C 1 ATOM 7241 O O . GLY B 1 407 ? -1.680 -8.655 17.041 1.00 20.00 ? 407 GLY B O 1 ATOM 7242 N N . HIS B 1 408 ? -1.130 -8.043 14.927 1.00 19.54 ? 408 HIS B N 1 ATOM 7243 C CA . HIS B 1 408 ? 0.320 -7.991 15.162 1.00 18.68 ? 408 HIS B CA 1 ATOM 7244 C C . HIS B 1 408 ? 0.611 -7.006 16.308 1.00 19.01 ? 408 HIS B C 1 ATOM 7245 O O . HIS B 1 408 ? -0.095 -6.016 16.422 1.00 19.74 ? 408 HIS B O 1 ATOM 7246 C CB . HIS B 1 408 ? 1.036 -7.596 13.860 1.00 19.06 ? 408 HIS B CB 1 ATOM 7247 C CG . HIS B 1 408 ? 2.517 -7.791 13.907 1.00 17.55 ? 408 HIS B CG 1 ATOM 7248 N ND1 . HIS B 1 408 ? 3.119 -8.978 13.554 1.00 18.19 ? 408 HIS B ND1 1 ATOM 7249 C CD2 . HIS B 1 408 ? 3.510 -6.978 14.340 1.00 20.05 ? 408 HIS B CD2 1 ATOM 7250 C CE1 . HIS B 1 408 ? 4.426 -8.884 13.747 1.00 16.96 ? 408 HIS B CE1 1 ATOM 7251 N NE2 . HIS B 1 408 ? 4.691 -7.684 14.234 1.00 16.47 ? 408 HIS B NE2 1 ATOM 7252 N N . PRO B 1 409 ? 1.609 -7.291 17.190 1.00 18.70 ? 409 PRO B N 1 ATOM 7253 C CA . PRO B 1 409 ? 2.009 -6.336 18.249 1.00 18.76 ? 409 PRO B CA 1 ATOM 7254 C C . PRO B 1 409 ? 2.450 -4.965 17.700 1.00 17.46 ? 409 PRO B C 1 ATOM 7255 O O . PRO B 1 409 ? 3.349 -4.890 16.865 1.00 17.99 ? 409 PRO B O 1 ATOM 7256 C CB . PRO B 1 409 ? 3.224 -7.019 18.904 1.00 17.07 ? 409 PRO B CB 1 ATOM 7257 C CG . PRO B 1 409 ? 3.691 -7.973 17.904 1.00 19.65 ? 409 PRO B CG 1 ATOM 7258 C CD . PRO B 1 409 ? 2.459 -8.492 17.246 1.00 18.93 ? 409 PRO B CD 1 ATOM 7259 N N . MET B 1 410 ? 1.834 -3.898 18.178 1.00 17.42 ? 410 MET B N 1 ATOM 7260 C CA . MET B 1 410 ? 2.153 -2.558 17.687 1.00 17.05 ? 410 MET B CA 1 ATOM 7261 C C . MET B 1 410 ? 1.659 -1.480 18.631 1.00 16.94 ? 410 MET B C 1 ATOM 7262 O O . MET B 1 410 ? 0.745 -1.699 19.444 1.00 17.38 ? 410 MET B O 1 ATOM 7263 C CB . MET B 1 410 ? 1.552 -2.313 16.292 1.00 16.88 ? 410 MET B CB 1 ATOM 7264 C CG . MET B 1 410 ? 0.027 -2.265 16.281 1.00 18.24 ? 410 MET B CG 1 ATOM 7265 S SD . MET B 1 410 ? -0.679 -1.983 14.635 1.00 17.84 ? 410 MET B SD 1 ATOM 7266 C CE . MET B 1 410 ? -0.335 -3.547 13.842 1.00 14.27 ? 410 MET B CE 1 ATOM 7267 N N . VAL B 1 411 ? 2.305 -0.322 18.515 1.00 15.88 ? 411 VAL B N 1 ATOM 7268 C CA . VAL B 1 411 ? 1.918 0.899 19.192 1.00 15.14 ? 411 VAL B CA 1 ATOM 7269 C C . VAL B 1 411 ? 1.830 2.016 18.151 1.00 15.05 ? 411 VAL B C 1 ATOM 7270 O O . VAL B 1 411 ? 2.469 1.946 17.065 1.00 14.54 ? 411 VAL B O 1 ATOM 7271 C CB . VAL B 1 411 ? 2.864 1.254 20.412 1.00 14.02 ? 411 VAL B CB 1 ATOM 7272 C CG1 . VAL B 1 411 ? 2.911 0.064 21.383 1.00 15.83 ? 411 VAL B CG1 1 ATOM 7273 C CG2 . VAL B 1 411 ? 4.314 1.629 19.945 1.00 15.01 ? 411 VAL B CG2 1 ATOM 7274 N N . ILE B 1 412 ? 1.000 3.013 18.456 1.00 14.73 ? 412 ILE B N 1 ATOM 7275 C CA . ILE B 1 412 ? 0.893 4.202 17.595 1.00 14.54 ? 412 ILE B CA 1 ATOM 7276 C C . ILE B 1 412 ? 1.618 5.360 18.251 1.00 15.19 ? 412 ILE B C 1 ATOM 7277 O O . ILE B 1 412 ? 1.493 5.591 19.468 1.00 14.42 ? 412 ILE B O 1 ATOM 7278 C CB . ILE B 1 412 ? -0.583 4.641 17.324 1.00 14.71 ? 412 ILE B CB 1 ATOM 7279 C CG1 . ILE B 1 412 ? -1.469 3.481 16.837 1.00 13.74 ? 412 ILE B CG1 1 ATOM 7280 C CG2 . ILE B 1 412 ? -0.634 5.860 16.358 1.00 13.78 ? 412 ILE B CG2 1 ATOM 7281 C CD1 . ILE B 1 412 ? -0.975 2.575 15.616 1.00 14.86 ? 412 ILE B CD1 1 ATOM 7282 N N . SER B 1 413 ? 2.373 6.103 17.444 1.00 15.28 ? 413 SER B N 1 ATOM 7283 C CA . SER B 1 413 ? 2.994 7.337 17.931 1.00 16.12 ? 413 SER B CA 1 ATOM 7284 C C . SER B 1 413 ? 2.987 8.385 16.823 1.00 16.20 ? 413 SER B C 1 ATOM 7285 O O . SER B 1 413 ? 2.501 8.117 15.740 1.00 16.60 ? 413 SER B O 1 ATOM 7286 C CB . SER B 1 413 ? 4.438 7.070 18.412 1.00 15.96 ? 413 SER B CB 1 ATOM 7287 O OG . SER B 1 413 ? 4.847 8.047 19.374 1.00 15.88 ? 413 SER B OG 1 ATOM 7288 N N . SER B 1 414 ? 3.547 9.562 17.091 1.00 18.07 ? 414 SER B N 1 ATOM 7289 C CA . SER B 1 414 ? 3.492 10.681 16.141 1.00 18.67 ? 414 SER B CA 1 ATOM 7290 C C . SER B 1 414 ? 4.852 11.151 15.521 1.00 19.28 ? 414 SER B C 1 ATOM 7291 O O . SER B 1 414 ? 4.863 11.954 14.557 1.00 19.17 ? 414 SER B O 1 ATOM 7292 C CB . SER B 1 414 ? 2.753 11.843 16.775 1.00 18.25 ? 414 SER B CB 1 ATOM 7293 O OG . SER B 1 414 ? 3.376 12.184 17.989 1.00 19.87 ? 414 SER B OG 1 ATOM 7294 N N . ASP B 1 415 ? 5.967 10.675 16.063 1.00 19.91 ? 415 ASP B N 1 ATOM 7295 C CA . ASP B 1 415 ? 7.304 10.861 15.437 1.00 21.51 ? 415 ASP B CA 1 ATOM 7296 C C . ASP B 1 415 ? 7.807 12.309 15.604 1.00 21.16 ? 415 ASP B C 1 ATOM 7297 O O . ASP B 1 415 ? 8.510 12.601 16.570 1.00 21.02 ? 415 ASP B O 1 ATOM 7298 C CB . ASP B 1 415 ? 7.293 10.400 13.964 1.00 21.67 ? 415 ASP B CB 1 ATOM 7299 C CG . ASP B 1 415 ? 8.680 10.121 13.403 1.00 26.14 ? 415 ASP B CG 1 ATOM 7300 O OD1 . ASP B 1 415 ? 9.598 9.869 14.197 1.00 28.23 ? 415 ASP B OD1 1 ATOM 7301 O OD2 . ASP B 1 415 ? 8.851 10.135 12.154 1.00 30.33 ? 415 ASP B OD2 1 ATOM 7302 N N . ASP B 1 416 ? 7.407 13.207 14.698 1.00 20.91 ? 416 ASP B N 1 ATOM 7303 C CA . ASP B 1 416 ? 7.773 14.617 14.764 1.00 21.23 ? 416 ASP B CA 1 ATOM 7304 C C . ASP B 1 416 ? 6.565 15.508 14.442 1.00 19.84 ? 416 ASP B C 1 ATOM 7305 O O . ASP B 1 416 ? 6.598 16.247 13.452 1.00 20.37 ? 416 ASP B O 1 ATOM 7306 C CB . ASP B 1 416 ? 8.917 14.906 13.780 1.00 22.24 ? 416 ASP B CB 1 ATOM 7307 C CG . ASP B 1 416 ? 10.283 14.492 14.323 1.00 26.43 ? 416 ASP B CG 1 ATOM 7308 O OD1 . ASP B 1 416 ? 10.659 14.919 15.448 1.00 32.35 ? 416 ASP B OD1 1 ATOM 7309 O OD2 . ASP B 1 416 ? 10.987 13.740 13.625 1.00 30.77 ? 416 ASP B OD2 1 ATOM 7310 N N . PRO B 1 417 ? 5.504 15.451 15.274 1.00 18.66 ? 417 PRO B N 1 ATOM 7311 C CA . PRO B 1 417 ? 4.227 16.053 14.879 1.00 18.41 ? 417 PRO B CA 1 ATOM 7312 C C . PRO B 1 417 ? 4.326 17.527 14.507 1.00 18.55 ? 417 PRO B C 1 ATOM 7313 O O . PRO B 1 417 ? 3.640 17.962 13.583 1.00 18.23 ? 417 PRO B O 1 ATOM 7314 C CB . PRO B 1 417 ? 3.330 15.873 16.120 1.00 18.64 ? 417 PRO B CB 1 ATOM 7315 C CG . PRO B 1 417 ? 4.297 15.586 17.264 1.00 18.19 ? 417 PRO B CG 1 ATOM 7316 C CD . PRO B 1 417 ? 5.420 14.818 16.602 1.00 18.12 ? 417 PRO B CD 1 ATOM 7317 N N . ALA B 1 418 ? 5.163 18.277 15.216 1.00 18.68 ? 418 ALA B N 1 ATOM 7318 C CA . ALA B 1 418 ? 5.307 19.729 14.977 1.00 19.71 ? 418 ALA B CA 1 ATOM 7319 C C . ALA B 1 418 ? 5.694 20.087 13.542 1.00 19.66 ? 418 ALA B C 1 ATOM 7320 O O . ALA B 1 418 ? 5.326 21.163 13.047 1.00 20.07 ? 418 ALA B O 1 ATOM 7321 C CB . ALA B 1 418 ? 6.326 20.320 15.945 1.00 18.99 ? 418 ALA B CB 1 ATOM 7322 N N . MET B 1 419 ? 6.468 19.215 12.893 1.00 19.67 ? 419 MET B N 1 ATOM 7323 C CA . MET B 1 419 ? 6.924 19.460 11.518 1.00 20.57 ? 419 MET B CA 1 ATOM 7324 C C . MET B 1 419 ? 5.837 19.256 10.469 1.00 19.37 ? 419 MET B C 1 ATOM 7325 O O . MET B 1 419 ? 6.002 19.683 9.332 1.00 19.24 ? 419 MET B O 1 ATOM 7326 C CB . MET B 1 419 ? 8.155 18.604 11.152 1.00 21.47 ? 419 MET B CB 1 ATOM 7327 C CG . MET B 1 419 ? 9.494 19.304 11.422 1.00 27.41 ? 419 MET B CG 1 ATOM 7328 S SD . MET B 1 419 ? 10.252 18.884 13.008 1.00 39.74 ? 419 MET B SD 1 ATOM 7329 C CE . MET B 1 419 ? 8.856 18.774 14.060 1.00 36.49 ? 419 MET B CE 1 ATOM 7330 N N . PHE B 1 420 ? 4.742 18.606 10.856 1.00 18.83 ? 420 PHE B N 1 ATOM 7331 C CA . PHE B 1 420 ? 3.686 18.207 9.925 1.00 18.76 ? 420 PHE B CA 1 ATOM 7332 C C . PHE B 1 420 ? 2.417 19.019 10.183 1.00 18.48 ? 420 PHE B C 1 ATOM 7333 O O . PHE B 1 420 ? 1.405 18.843 9.501 1.00 17.52 ? 420 PHE B O 1 ATOM 7334 C CB . PHE B 1 420 ? 3.345 16.714 10.112 1.00 19.01 ? 420 PHE B CB 1 ATOM 7335 C CG . PHE B 1 420 ? 4.548 15.783 10.155 1.00 19.81 ? 420 PHE B CG 1 ATOM 7336 C CD1 . PHE B 1 420 ? 5.641 15.956 9.300 1.00 21.99 ? 420 PHE B CD1 1 ATOM 7337 C CD2 . PHE B 1 420 ? 4.550 14.689 11.021 1.00 20.06 ? 420 PHE B CD2 1 ATOM 7338 C CE1 . PHE B 1 420 ? 6.740 15.068 9.342 1.00 20.85 ? 420 PHE B CE1 1 ATOM 7339 C CE2 . PHE B 1 420 ? 5.640 13.816 11.073 1.00 21.02 ? 420 PHE B CE2 1 ATOM 7340 C CZ . PHE B 1 420 ? 6.737 14.014 10.232 1.00 21.42 ? 420 PHE B CZ 1 ATOM 7341 N N . GLY B 1 421 ? 2.454 19.839 11.230 1.00 18.37 ? 421 GLY B N 1 ATOM 7342 C CA . GLY B 1 421 ? 1.268 20.566 11.674 1.00 18.27 ? 421 GLY B CA 1 ATOM 7343 C C . GLY B 1 421 ? 0.360 19.742 12.571 1.00 19.42 ? 421 GLY B C 1 ATOM 7344 O O . GLY B 1 421 ? -0.823 20.079 12.738 1.00 18.68 ? 421 GLY B O 1 ATOM 7345 N N . ALA B 1 422 ? 0.884 18.657 13.150 1.00 17.32 ? 422 ALA B N 1 ATOM 7346 C CA . ALA B 1 422 ? 0.112 17.895 14.113 1.00 17.66 ? 422 ALA B CA 1 ATOM 7347 C C . ALA B 1 422 ? 0.529 18.264 15.560 1.00 18.20 ? 422 ALA B C 1 ATOM 7348 O O . ALA B 1 422 ? 1.463 19.036 15.797 1.00 18.34 ? 422 ALA B O 1 ATOM 7349 C CB . ALA B 1 422 ? 0.277 16.363 13.869 1.00 17.62 ? 422 ALA B CB 1 ATOM 7350 N N . LYS B 1 423 ? -0.161 17.675 16.514 1.00 18.41 ? 423 LYS B N 1 ATOM 7351 C CA . LYS B 1 423 ? 0.069 17.925 17.917 1.00 20.16 ? 423 LYS B CA 1 ATOM 7352 C C . LYS B 1 423 ? -0.284 16.634 18.687 1.00 18.91 ? 423 LYS B C 1 ATOM 7353 O O . LYS B 1 423 ? -1.321 16.010 18.419 1.00 19.59 ? 423 LYS B O 1 ATOM 7354 C CB . LYS B 1 423 ? -0.838 19.112 18.341 1.00 20.96 ? 423 LYS B CB 1 ATOM 7355 C CG . LYS B 1 423 ? -0.481 19.741 19.688 1.00 26.28 ? 423 LYS B CG 1 ATOM 7356 C CD . LYS B 1 423 ? -1.571 20.720 20.179 1.00 29.27 ? 423 LYS B CD 1 ATOM 7357 C CE . LYS B 1 423 ? -2.040 21.620 19.043 1.00 33.24 ? 423 LYS B CE 1 ATOM 7358 N NZ . LYS B 1 423 ? -0.922 22.378 18.400 1.00 38.02 ? 423 LYS B NZ 1 ATOM 7359 N N . GLY B 1 424 ? 0.570 16.224 19.625 1.00 18.19 ? 424 GLY B N 1 ATOM 7360 C CA . GLY B 1 424 ? 0.309 15.050 20.441 1.00 16.97 ? 424 GLY B CA 1 ATOM 7361 C C . GLY B 1 424 ? 0.147 13.764 19.622 1.00 16.89 ? 424 GLY B C 1 ATOM 7362 O O . GLY B 1 424 ? 0.857 13.543 18.623 1.00 15.86 ? 424 GLY B O 1 ATOM 7363 N N . LEU B 1 425 ? -0.818 12.946 20.041 1.00 15.56 ? 425 LEU B N 1 ATOM 7364 C CA . LEU B 1 425 ? -1.108 11.662 19.433 1.00 15.83 ? 425 LEU B CA 1 ATOM 7365 C C . LEU B 1 425 ? -2.457 11.535 18.665 1.00 15.34 ? 425 LEU B C 1 ATOM 7366 O O . LEU B 1 425 ? -2.604 10.623 17.849 1.00 15.17 ? 425 LEU B O 1 ATOM 7367 C CB . LEU B 1 425 ? -1.023 10.596 20.532 1.00 16.29 ? 425 LEU B CB 1 ATOM 7368 C CG . LEU B 1 425 ? 0.117 9.582 20.583 1.00 19.15 ? 425 LEU B CG 1 ATOM 7369 C CD1 . LEU B 1 425 ? 1.486 10.038 20.052 1.00 19.18 ? 425 LEU B CD1 1 ATOM 7370 C CD2 . LEU B 1 425 ? 0.243 8.933 21.952 1.00 19.66 ? 425 LEU B CD2 1 ATOM 7371 N N . SER B 1 426 ? -3.425 12.428 18.892 1.00 14.32 ? 426 SER B N 1 ATOM 7372 C CA . SER B 1 426 ? -4.801 12.205 18.362 1.00 14.79 ? 426 SER B CA 1 ATOM 7373 C C . SER B 1 426 ? -4.938 12.177 16.829 1.00 14.96 ? 426 SER B C 1 ATOM 7374 O O . SER B 1 426 ? -5.797 11.495 16.311 1.00 14.14 ? 426 SER B O 1 ATOM 7375 C CB . SER B 1 426 ? -5.808 13.219 18.915 1.00 14.38 ? 426 SER B CB 1 ATOM 7376 O OG . SER B 1 426 ? -5.770 13.198 20.326 1.00 17.90 ? 426 SER B OG 1 ATOM 7377 N N . TYR B 1 427 ? -4.117 12.946 16.128 1.00 15.65 ? 427 TYR B N 1 ATOM 7378 C CA . TYR B 1 427 ? -4.197 12.975 14.662 1.00 16.47 ? 427 TYR B CA 1 ATOM 7379 C C . TYR B 1 427 ? -3.724 11.650 14.068 1.00 15.34 ? 427 TYR B C 1 ATOM 7380 O O . TYR B 1 427 ? -4.305 11.156 13.146 1.00 15.14 ? 427 TYR B O 1 ATOM 7381 C CB . TYR B 1 427 ? -3.339 14.106 14.095 1.00 16.59 ? 427 TYR B CB 1 ATOM 7382 C CG . TYR B 1 427 ? -3.828 15.503 14.407 1.00 18.80 ? 427 TYR B CG 1 ATOM 7383 C CD1 . TYR B 1 427 ? -3.317 16.198 15.502 1.00 19.89 ? 427 TYR B CD1 1 ATOM 7384 C CD2 . TYR B 1 427 ? -4.794 16.141 13.593 1.00 19.52 ? 427 TYR B CD2 1 ATOM 7385 C CE1 . TYR B 1 427 ? -3.759 17.494 15.801 1.00 23.45 ? 427 TYR B CE1 1 ATOM 7386 C CE2 . TYR B 1 427 ? -5.224 17.455 13.882 1.00 21.63 ? 427 TYR B CE2 1 ATOM 7387 C CZ . TYR B 1 427 ? -4.689 18.106 14.995 1.00 20.71 ? 427 TYR B CZ 1 ATOM 7388 O OH . TYR B 1 427 ? -5.062 19.377 15.315 1.00 28.49 ? 427 TYR B OH 1 ATOM 7389 N N . ASP B 1 428 ? -2.636 11.112 14.599 1.00 15.75 ? 428 ASP B N 1 ATOM 7390 C CA . ASP B 1 428 ? -2.190 9.762 14.238 1.00 16.34 ? 428 ASP B CA 1 ATOM 7391 C C . ASP B 1 428 ? -3.178 8.631 14.625 1.00 15.13 ? 428 ASP B C 1 ATOM 7392 O O . ASP B 1 428 ? -3.426 7.706 13.839 1.00 14.03 ? 428 ASP B O 1 ATOM 7393 C CB . ASP B 1 428 ? -0.787 9.545 14.782 1.00 17.20 ? 428 ASP B CB 1 ATOM 7394 C CG . ASP B 1 428 ? 0.264 10.405 14.019 1.00 19.93 ? 428 ASP B CG 1 ATOM 7395 O OD1 . ASP B 1 428 ? 0.723 9.941 12.943 1.00 22.86 ? 428 ASP B OD1 1 ATOM 7396 O OD2 . ASP B 1 428 ? 0.589 11.552 14.470 1.00 22.16 ? 428 ASP B OD2 1 ATOM 7397 N N . PHE B 1 429 ? -3.758 8.712 15.810 1.00 13.20 ? 429 PHE B N 1 ATOM 7398 C CA . PHE B 1 429 ? -4.840 7.791 16.170 1.00 13.51 ? 429 PHE B CA 1 ATOM 7399 C C . PHE B 1 429 ? -6.046 7.879 15.191 1.00 12.41 ? 429 PHE B C 1 ATOM 7400 O O . PHE B 1 429 ? -6.635 6.857 14.833 1.00 12.71 ? 429 PHE B O 1 ATOM 7401 C CB . PHE B 1 429 ? -5.313 7.979 17.646 1.00 13.11 ? 429 PHE B CB 1 ATOM 7402 C CG . PHE B 1 429 ? -4.638 7.043 18.649 1.00 15.26 ? 429 PHE B CG 1 ATOM 7403 C CD1 . PHE B 1 429 ? -3.334 7.294 19.100 1.00 17.22 ? 429 PHE B CD1 1 ATOM 7404 C CD2 . PHE B 1 429 ? -5.310 5.929 19.146 1.00 17.25 ? 429 PHE B CD2 1 ATOM 7405 C CE1 . PHE B 1 429 ? -2.687 6.455 20.035 1.00 16.68 ? 429 PHE B CE1 1 ATOM 7406 C CE2 . PHE B 1 429 ? -4.676 5.052 20.073 1.00 18.13 ? 429 PHE B CE2 1 ATOM 7407 C CZ . PHE B 1 429 ? -3.358 5.326 20.524 1.00 15.39 ? 429 PHE B CZ 1 ATOM 7408 N N . TYR B 1 430 ? -6.437 9.083 14.779 1.00 11.82 ? 430 TYR B N 1 ATOM 7409 C CA . TYR B 1 430 ? -7.495 9.206 13.765 1.00 11.11 ? 430 TYR B CA 1 ATOM 7410 C C . TYR B 1 430 ? -7.124 8.484 12.439 1.00 11.59 ? 430 TYR B C 1 ATOM 7411 O O . TYR B 1 430 ? -7.918 7.735 11.872 1.00 10.29 ? 430 TYR B O 1 ATOM 7412 C CB . TYR B 1 430 ? -7.760 10.712 13.500 1.00 11.83 ? 430 TYR B CB 1 ATOM 7413 C CG . TYR B 1 430 ? -8.715 10.929 12.344 1.00 12.63 ? 430 TYR B CG 1 ATOM 7414 C CD1 . TYR B 1 430 ? -8.251 10.913 11.026 1.00 13.14 ? 430 TYR B CD1 1 ATOM 7415 C CD2 . TYR B 1 430 ? -10.100 11.082 12.562 1.00 14.01 ? 430 TYR B CD2 1 ATOM 7416 C CE1 . TYR B 1 430 ? -9.121 11.080 9.944 1.00 14.38 ? 430 TYR B CE1 1 ATOM 7417 C CE2 . TYR B 1 430 ? -10.973 11.283 11.492 1.00 14.76 ? 430 TYR B CE2 1 ATOM 7418 C CZ . TYR B 1 430 ? -10.473 11.278 10.190 1.00 15.32 ? 430 TYR B CZ 1 ATOM 7419 O OH . TYR B 1 430 ? -11.300 11.438 9.113 1.00 17.07 ? 430 TYR B OH 1 ATOM 7420 N N . GLU B 1 431 ? -5.889 8.684 11.969 1.00 12.43 ? 431 GLU B N 1 ATOM 7421 C CA . GLU B 1 431 ? -5.474 8.081 10.696 1.00 13.99 ? 431 GLU B CA 1 ATOM 7422 C C . GLU B 1 431 ? -5.506 6.553 10.800 1.00 13.96 ? 431 GLU B C 1 ATOM 7423 O O . GLU B 1 431 ? -5.971 5.853 9.892 1.00 13.92 ? 431 GLU B O 1 ATOM 7424 C CB . GLU B 1 431 ? -4.068 8.562 10.301 1.00 13.59 ? 431 GLU B CB 1 ATOM 7425 C CG . GLU B 1 431 ? -3.940 10.077 10.104 1.00 14.19 ? 431 GLU B CG 1 ATOM 7426 C CD . GLU B 1 431 ? -4.534 10.633 8.790 1.00 16.66 ? 431 GLU B CD 1 ATOM 7427 O OE1 . GLU B 1 431 ? -5.519 10.079 8.257 1.00 12.27 ? 431 GLU B OE1 1 ATOM 7428 O OE2 . GLU B 1 431 ? -4.012 11.673 8.305 1.00 17.38 ? 431 GLU B OE2 1 ATOM 7429 N N . VAL B 1 432 ? -5.032 6.035 11.920 1.00 14.84 ? 432 VAL B N 1 ATOM 7430 C CA . VAL B 1 432 ? -5.045 4.572 12.149 1.00 14.87 ? 432 VAL B CA 1 ATOM 7431 C C . VAL B 1 432 ? -6.511 4.045 12.234 1.00 15.00 ? 432 VAL B C 1 ATOM 7432 O O . VAL B 1 432 ? -6.912 3.098 11.539 1.00 15.35 ? 432 VAL B O 1 ATOM 7433 C CB . VAL B 1 432 ? -4.258 4.219 13.429 1.00 14.61 ? 432 VAL B CB 1 ATOM 7434 C CG1 . VAL B 1 432 ? -4.517 2.763 13.832 1.00 14.74 ? 432 VAL B CG1 1 ATOM 7435 C CG2 . VAL B 1 432 ? -2.756 4.463 13.236 1.00 15.87 ? 432 VAL B CG2 1 ATOM 7436 N N . PHE B 1 433 ? -7.326 4.702 13.045 1.00 15.85 ? 433 PHE B N 1 ATOM 7437 C CA . PHE B 1 433 ? -8.693 4.218 13.314 1.00 15.81 ? 433 PHE B CA 1 ATOM 7438 C C . PHE B 1 433 ? -9.659 4.332 12.123 1.00 16.81 ? 433 PHE B C 1 ATOM 7439 O O . PHE B 1 433 ? -10.564 3.475 11.934 1.00 16.08 ? 433 PHE B O 1 ATOM 7440 C CB . PHE B 1 433 ? -9.245 4.983 14.523 1.00 15.81 ? 433 PHE B CB 1 ATOM 7441 C CG . PHE B 1 433 ? -10.593 4.514 14.982 1.00 17.15 ? 433 PHE B CG 1 ATOM 7442 C CD1 . PHE B 1 433 ? -10.770 3.228 15.484 1.00 18.89 ? 433 PHE B CD1 1 ATOM 7443 C CD2 . PHE B 1 433 ? -11.684 5.358 14.933 1.00 17.66 ? 433 PHE B CD2 1 ATOM 7444 C CE1 . PHE B 1 433 ? -12.019 2.810 15.923 1.00 17.85 ? 433 PHE B CE1 1 ATOM 7445 C CE2 . PHE B 1 433 ? -12.939 4.941 15.384 1.00 18.31 ? 433 PHE B CE2 1 ATOM 7446 C CZ . PHE B 1 433 ? -13.098 3.668 15.878 1.00 17.79 ? 433 PHE B CZ 1 ATOM 7447 N N . MET B 1 434 ? -9.501 5.401 11.337 1.00 17.44 ? 434 MET B N 1 ATOM 7448 C CA . MET B 1 434 ? -10.346 5.618 10.170 1.00 18.07 ? 434 MET B CA 1 ATOM 7449 C C . MET B 1 434 ? -9.723 5.085 8.871 1.00 18.77 ? 434 MET B C 1 ATOM 7450 O O . MET B 1 434 ? -10.423 4.487 8.052 1.00 18.99 ? 434 MET B O 1 ATOM 7451 C CB . MET B 1 434 ? -10.669 7.109 10.008 1.00 18.13 ? 434 MET B CB 1 ATOM 7452 C CG . MET B 1 434 ? -11.449 7.701 11.209 1.00 20.25 ? 434 MET B CG 1 ATOM 7453 S SD . MET B 1 434 ? -13.136 7.041 11.282 1.00 23.17 ? 434 MET B SD 1 ATOM 7454 C CE . MET B 1 434 ? -13.910 7.830 9.889 1.00 25.55 ? 434 MET B CE 1 ATOM 7455 N N . GLY B 1 435 ? -8.427 5.335 8.666 1.00 18.83 ? 435 GLY B N 1 ATOM 7456 C CA . GLY B 1 435 ? -7.781 4.995 7.398 1.00 18.17 ? 435 GLY B CA 1 ATOM 7457 C C . GLY B 1 435 ? -7.232 3.575 7.342 1.00 18.45 ? 435 GLY B C 1 ATOM 7458 O O . GLY B 1 435 ? -7.534 2.817 6.432 1.00 20.23 ? 435 GLY B O 1 ATOM 7459 N N . ILE B 1 436 ? -6.401 3.212 8.299 1.00 17.56 ? 436 ILE B N 1 ATOM 7460 C CA . ILE B 1 436 ? -5.596 2.003 8.171 1.00 16.15 ? 436 ILE B CA 1 ATOM 7461 C C . ILE B 1 436 ? -6.353 0.755 8.607 1.00 15.67 ? 436 ILE B C 1 ATOM 7462 O O . ILE B 1 436 ? -6.284 -0.295 7.958 1.00 16.05 ? 436 ILE B O 1 ATOM 7463 C CB . ILE B 1 436 ? -4.234 2.175 8.902 1.00 15.88 ? 436 ILE B CB 1 ATOM 7464 C CG1 . ILE B 1 436 ? -3.510 3.435 8.394 1.00 15.54 ? 436 ILE B CG1 1 ATOM 7465 C CG2 . ILE B 1 436 ? -3.354 0.884 8.749 1.00 15.16 ? 436 ILE B CG2 1 ATOM 7466 C CD1 . ILE B 1 436 ? -2.134 3.708 9.026 1.00 16.32 ? 436 ILE B CD1 1 ATOM 7467 N N . GLY B 1 437 ? -7.095 0.877 9.701 1.00 15.95 ? 437 GLY B N 1 ATOM 7468 C CA . GLY B 1 437 ? -7.798 -0.263 10.290 1.00 15.65 ? 437 GLY B CA 1 ATOM 7469 C C . GLY B 1 437 ? -9.130 -0.556 9.643 1.00 16.35 ? 437 GLY B C 1 ATOM 7470 O O . GLY B 1 437 ? -9.749 -1.560 9.948 1.00 17.48 ? 437 GLY B O 1 ATOM 7471 N N . GLY B 1 438 ? -9.582 0.320 8.751 1.00 16.45 ? 438 GLY B N 1 ATOM 7472 C CA . GLY B 1 438 ? -10.830 0.085 8.031 1.00 16.27 ? 438 GLY B CA 1 ATOM 7473 C C . GLY B 1 438 ? -12.089 0.324 8.842 1.00 16.81 ? 438 GLY B C 1 ATOM 7474 O O . GLY B 1 438 ? -12.019 0.707 10.021 1.00 15.22 ? 438 GLY B O 1 ATOM 7475 N N . MET B 1 439 ? -13.245 0.103 8.204 1.00 17.50 ? 439 MET B N 1 ATOM 7476 C CA . MET B 1 439 ? -14.561 0.405 8.808 1.00 18.45 ? 439 MET B CA 1 ATOM 7477 C C . MET B 1 439 ? -14.860 -0.444 10.049 1.00 18.39 ? 439 MET B C 1 ATOM 7478 O O . MET B 1 439 ? -15.560 -0.014 10.957 1.00 18.49 ? 439 MET B O 1 ATOM 7479 C CB . MET B 1 439 ? -15.680 0.226 7.765 1.00 19.53 ? 439 MET B CB 1 ATOM 7480 C CG . MET B 1 439 ? -17.059 0.820 8.212 1.00 24.40 ? 439 MET B CG 1 ATOM 7481 S SD . MET B 1 439 ? -18.367 0.652 6.966 1.00 36.07 ? 439 MET B SD 1 ATOM 7482 C CE . MET B 1 439 ? -18.063 2.157 6.079 1.00 26.70 ? 439 MET B CE 1 ATOM 7483 N N . LYS B 1 440 ? -14.318 -1.646 10.102 1.00 19.02 ? 440 LYS B N 1 ATOM 7484 C CA . LYS B 1 440 ? -14.546 -2.520 11.247 1.00 19.31 ? 440 LYS B CA 1 ATOM 7485 C C . LYS B 1 440 ? -13.704 -2.230 12.497 1.00 19.26 ? 440 LYS B C 1 ATOM 7486 O O . LYS B 1 440 ? -14.009 -2.787 13.565 1.00 19.85 ? 440 LYS B O 1 ATOM 7487 C CB . LYS B 1 440 ? -14.327 -3.987 10.843 1.00 20.00 ? 440 LYS B CB 1 ATOM 7488 C CG . LYS B 1 440 ? -15.336 -4.579 9.845 1.00 23.00 ? 440 LYS B CG 1 ATOM 7489 C CD . LYS B 1 440 ? -16.748 -4.322 10.262 1.00 26.66 ? 440 LYS B CD 1 ATOM 7490 C CE . LYS B 1 440 ? -17.700 -5.467 9.892 1.00 30.21 ? 440 LYS B CE 1 ATOM 7491 N NZ . LYS B 1 440 ? -17.562 -6.063 8.545 1.00 32.56 ? 440 LYS B NZ 1 ATOM 7492 N N . ALA B 1 441 ? -12.628 -1.434 12.397 1.00 18.41 ? 441 ALA B N 1 ATOM 7493 C CA . ALA B 1 441 ? -11.871 -1.086 13.617 1.00 18.40 ? 441 ALA B CA 1 ATOM 7494 C C . ALA B 1 441 ? -12.805 -0.348 14.573 1.00 18.70 ? 441 ALA B C 1 ATOM 7495 O O . ALA B 1 441 ? -13.526 0.570 14.165 1.00 18.19 ? 441 ALA B O 1 ATOM 7496 C CB . ALA B 1 441 ? -10.623 -0.232 13.329 1.00 17.64 ? 441 ALA B CB 1 ATOM 7497 N N . ASP B 1 442 ? -12.767 -0.751 15.837 1.00 18.44 ? 442 ASP B N 1 ATOM 7498 C CA . ASP B 1 442 ? -13.776 -0.328 16.809 1.00 18.14 ? 442 ASP B CA 1 ATOM 7499 C C . ASP B 1 442 ? -13.147 0.064 18.162 1.00 17.72 ? 442 ASP B C 1 ATOM 7500 O O . ASP B 1 442 ? -11.906 0.222 18.282 1.00 15.98 ? 442 ASP B O 1 ATOM 7501 C CB . ASP B 1 442 ? -14.861 -1.431 16.936 1.00 18.66 ? 442 ASP B CB 1 ATOM 7502 C CG . ASP B 1 442 ? -14.358 -2.707 17.658 1.00 21.09 ? 442 ASP B CG 1 ATOM 7503 O OD1 . ASP B 1 442 ? -13.190 -2.774 18.082 1.00 19.81 ? 442 ASP B OD1 1 ATOM 7504 O OD2 . ASP B 1 442 ? -15.149 -3.667 17.817 1.00 24.90 ? 442 ASP B OD2 1 ATOM 7505 N N . LEU B 1 443 ? -13.984 0.245 19.186 1.00 17.23 ? 443 LEU B N 1 ATOM 7506 C CA . LEU B 1 443 ? -13.463 0.581 20.508 1.00 17.59 ? 443 LEU B CA 1 ATOM 7507 C C . LEU B 1 443 ? -12.406 -0.412 21.045 1.00 17.29 ? 443 LEU B C 1 ATOM 7508 O O . LEU B 1 443 ? -11.479 0.010 21.749 1.00 18.33 ? 443 LEU B O 1 ATOM 7509 C CB . LEU B 1 443 ? -14.612 0.721 21.536 1.00 18.37 ? 443 LEU B CB 1 ATOM 7510 C CG . LEU B 1 443 ? -14.296 1.308 22.924 1.00 18.32 ? 443 LEU B CG 1 ATOM 7511 C CD1 . LEU B 1 443 ? -13.967 2.794 22.889 1.00 19.38 ? 443 LEU B CD1 1 ATOM 7512 C CD2 . LEU B 1 443 ? -15.473 1.043 23.926 1.00 20.06 ? 443 LEU B CD2 1 ATOM 7513 N N . ARG B 1 444 ? -12.527 -1.704 20.729 1.00 16.89 ? 444 ARG B N 1 ATOM 7514 C CA . ARG B 1 444 ? -11.539 -2.707 21.189 1.00 17.15 ? 444 ARG B CA 1 ATOM 7515 C C . ARG B 1 444 ? -10.177 -2.438 20.523 1.00 17.21 ? 444 ARG B C 1 ATOM 7516 O O . ARG B 1 444 ? -9.140 -2.566 21.178 1.00 17.62 ? 444 ARG B O 1 ATOM 7517 C CB . ARG B 1 444 ? -11.973 -4.135 20.869 1.00 16.69 ? 444 ARG B CB 1 ATOM 7518 C CG . ARG B 1 444 ? -13.287 -4.591 21.526 1.00 18.77 ? 444 ARG B CG 1 ATOM 7519 C CD . ARG B 1 444 ? -13.761 -5.920 20.955 1.00 19.22 ? 444 ARG B CD 1 ATOM 7520 N NE . ARG B 1 444 ? -15.014 -6.367 21.602 1.00 22.22 ? 444 ARG B NE 1 ATOM 7521 C CZ . ARG B 1 444 ? -16.220 -5.927 21.276 1.00 22.86 ? 444 ARG B CZ 1 ATOM 7522 N NH1 . ARG B 1 444 ? -16.351 -5.019 20.309 1.00 19.07 ? 444 ARG B NH1 1 ATOM 7523 N NH2 . ARG B 1 444 ? -17.295 -6.389 21.910 1.00 22.41 ? 444 ARG B NH2 1 ATOM 7524 N N . THR B 1 445 ? -10.196 -2.079 19.228 1.00 16.58 ? 445 THR B N 1 ATOM 7525 C CA . THR B 1 445 ? -8.973 -1.612 18.522 1.00 16.44 ? 445 THR B CA 1 ATOM 7526 C C . THR B 1 445 ? -8.268 -0.512 19.304 1.00 16.57 ? 445 THR B C 1 ATOM 7527 O O . THR B 1 445 ? -7.065 -0.608 19.597 1.00 15.99 ? 445 THR B O 1 ATOM 7528 C CB . THR B 1 445 ? -9.281 -1.107 17.091 1.00 16.60 ? 445 THR B CB 1 ATOM 7529 O OG1 . THR B 1 445 ? -9.982 -2.131 16.381 1.00 16.57 ? 445 THR B OG1 1 ATOM 7530 C CG2 . THR B 1 445 ? -7.982 -0.715 16.306 1.00 14.90 ? 445 THR B CG2 1 ATOM 7531 N N . LEU B 1 446 ? -9.023 0.518 19.666 1.00 16.58 ? 446 LEU B N 1 ATOM 7532 C CA . LEU B 1 446 ? -8.474 1.665 20.383 1.00 16.67 ? 446 LEU B CA 1 ATOM 7533 C C . LEU B 1 446 ? -7.940 1.334 21.766 1.00 16.87 ? 446 LEU B C 1 ATOM 7534 O O . LEU B 1 446 ? -6.843 1.780 22.121 1.00 16.91 ? 446 LEU B O 1 ATOM 7535 C CB . LEU B 1 446 ? -9.502 2.778 20.472 1.00 16.20 ? 446 LEU B CB 1 ATOM 7536 C CG . LEU B 1 446 ? -10.008 3.278 19.102 1.00 17.82 ? 446 LEU B CG 1 ATOM 7537 C CD1 . LEU B 1 446 ? -11.202 4.161 19.355 1.00 18.00 ? 446 LEU B CD1 1 ATOM 7538 C CD2 . LEU B 1 446 ? -8.934 4.062 18.312 1.00 13.70 ? 446 LEU B CD2 1 ATOM 7539 N N . LYS B 1 447 ? -8.720 0.573 22.543 1.00 16.93 ? 447 LYS B N 1 ATOM 7540 C CA . LYS B 1 447 ? -8.324 0.124 23.874 1.00 17.46 ? 447 LYS B CA 1 ATOM 7541 C C . LYS B 1 447 ? -7.060 -0.766 23.836 1.00 17.99 ? 447 LYS B C 1 ATOM 7542 O O . LYS B 1 447 ? -6.160 -0.597 24.638 1.00 18.50 ? 447 LYS B O 1 ATOM 7543 C CB . LYS B 1 447 ? -9.481 -0.643 24.555 1.00 18.12 ? 447 LYS B CB 1 ATOM 7544 C CG . LYS B 1 447 ? -9.351 -0.773 26.085 1.00 17.67 ? 447 LYS B CG 1 ATOM 7545 C CD . LYS B 1 447 ? -10.465 -1.705 26.651 1.00 18.17 ? 447 LYS B CD 1 ATOM 7546 C CE . LYS B 1 447 ? -10.489 -1.620 28.166 1.00 20.00 ? 447 LYS B CE 1 ATOM 7547 N NZ . LYS B 1 447 ? -11.451 -2.594 28.740 1.00 24.95 ? 447 LYS B NZ 1 ATOM 7548 N N . GLN B 1 448 ? -6.987 -1.697 22.896 1.00 18.47 ? 448 GLN B N 1 ATOM 7549 C CA . GLN B 1 448 ? -5.782 -2.501 22.752 1.00 18.32 ? 448 GLN B CA 1 ATOM 7550 C C . GLN B 1 448 ? -4.534 -1.669 22.467 1.00 18.00 ? 448 GLN B C 1 ATOM 7551 O O . GLN B 1 448 ? -3.480 -1.943 23.025 1.00 18.42 ? 448 GLN B O 1 ATOM 7552 C CB . GLN B 1 448 ? -5.954 -3.535 21.647 1.00 18.91 ? 448 GLN B CB 1 ATOM 7553 C CG . GLN B 1 448 ? -4.839 -4.586 21.627 1.00 19.06 ? 448 GLN B CG 1 ATOM 7554 C CD . GLN B 1 448 ? -4.937 -5.520 22.824 1.00 22.23 ? 448 GLN B CD 1 ATOM 7555 O OE1 . GLN B 1 448 ? -5.931 -6.207 22.980 1.00 24.11 ? 448 GLN B OE1 1 ATOM 7556 N NE2 . GLN B 1 448 ? -3.916 -5.529 23.680 1.00 23.85 ? 448 GLN B NE2 1 ATOM 7557 N N . LEU B 1 449 ? -4.643 -0.665 21.596 1.00 16.83 ? 449 LEU B N 1 ATOM 7558 C CA . LEU B 1 449 ? -3.488 0.146 21.231 1.00 16.03 ? 449 LEU B CA 1 ATOM 7559 C C . LEU B 1 449 ? -3.002 1.004 22.412 1.00 16.14 ? 449 LEU B C 1 ATOM 7560 O O . LEU B 1 449 ? -1.773 1.172 22.616 1.00 15.06 ? 449 LEU B O 1 ATOM 7561 C CB . LEU B 1 449 ? -3.799 1.026 20.005 1.00 16.08 ? 449 LEU B CB 1 ATOM 7562 C CG . LEU B 1 449 ? -3.978 0.351 18.628 1.00 14.58 ? 449 LEU B CG 1 ATOM 7563 C CD1 . LEU B 1 449 ? -4.690 1.342 17.655 1.00 14.47 ? 449 LEU B CD1 1 ATOM 7564 C CD2 . LEU B 1 449 ? -2.636 -0.078 18.095 1.00 13.17 ? 449 LEU B CD2 1 ATOM 7565 N N . ALA B 1 450 ? -3.957 1.559 23.167 1.00 15.53 ? 450 ALA B N 1 ATOM 7566 C CA . ALA B 1 450 ? -3.645 2.330 24.382 1.00 16.35 ? 450 ALA B CA 1 ATOM 7567 C C . ALA B 1 450 ? -2.924 1.421 25.387 1.00 16.83 ? 450 ALA B C 1 ATOM 7568 O O . ALA B 1 450 ? -1.852 1.751 25.909 1.00 17.18 ? 450 ALA B O 1 ATOM 7569 C CB . ALA B 1 450 ? -4.938 2.899 25.010 1.00 16.50 ? 450 ALA B CB 1 ATOM 7570 N N . MET B 1 451 ? -3.515 0.267 25.644 1.00 16.81 ? 451 MET B N 1 ATOM 7571 C CA . MET B 1 451 ? -2.918 -0.683 26.568 1.00 17.70 ? 451 MET B CA 1 ATOM 7572 C C . MET B 1 451 ? -1.545 -1.204 26.104 1.00 17.45 ? 451 MET B C 1 ATOM 7573 O O . MET B 1 451 ? -0.627 -1.306 26.916 1.00 16.76 ? 451 MET B O 1 ATOM 7574 C CB . MET B 1 451 ? -3.869 -1.826 26.853 1.00 17.32 ? 451 MET B CB 1 ATOM 7575 C CG . MET B 1 451 ? -5.085 -1.362 27.679 1.00 19.22 ? 451 MET B CG 1 ATOM 7576 S SD . MET B 1 451 ? -6.081 -2.756 28.261 1.00 26.35 ? 451 MET B SD 1 ATOM 7577 C CE . MET B 1 451 ? -6.330 -3.655 26.750 1.00 19.16 ? 451 MET B CE 1 ATOM 7578 N N . ASN B 1 452 ? -1.421 -1.508 24.811 1.00 17.06 ? 452 ASN B N 1 ATOM 7579 C CA . ASN B 1 452 ? -0.125 -1.859 24.217 1.00 17.08 ? 452 ASN B CA 1 ATOM 7580 C C . ASN B 1 452 ? 0.981 -0.876 24.520 1.00 16.48 ? 452 ASN B C 1 ATOM 7581 O O . ASN B 1 452 ? 2.128 -1.283 24.734 1.00 16.27 ? 452 ASN B O 1 ATOM 7582 C CB . ASN B 1 452 ? -0.215 -2.044 22.687 1.00 16.45 ? 452 ASN B CB 1 ATOM 7583 C CG . ASN B 1 452 ? -0.846 -3.361 22.295 1.00 18.26 ? 452 ASN B CG 1 ATOM 7584 O OD1 . ASN B 1 452 ? -1.131 -4.211 23.149 1.00 19.12 ? 452 ASN B OD1 1 ATOM 7585 N ND2 . ASN B 1 452 ? -1.047 -3.555 20.992 1.00 18.35 ? 452 ASN B ND2 1 ATOM 7586 N N . SER B 1 453 ? 0.657 0.406 24.548 1.00 16.51 ? 453 SER B N 1 ATOM 7587 C CA . SER B 1 453 ? 1.696 1.412 24.717 1.00 18.32 ? 453 SER B CA 1 ATOM 7588 C C . SER B 1 453 ? 2.226 1.462 26.162 1.00 18.39 ? 453 SER B C 1 ATOM 7589 O O . SER B 1 453 ? 3.314 1.989 26.397 1.00 17.17 ? 453 SER B O 1 ATOM 7590 C CB . SER B 1 453 ? 1.248 2.806 24.225 1.00 17.96 ? 453 SER B CB 1 ATOM 7591 O OG . SER B 1 453 ? 0.296 3.398 25.107 1.00 19.05 ? 453 SER B OG 1 ATOM 7592 N N . ILE B 1 454 ? 1.461 0.894 27.102 1.00 18.51 ? 454 ILE B N 1 ATOM 7593 C CA . ILE B 1 454 ? 1.929 0.708 28.475 1.00 18.75 ? 454 ILE B CA 1 ATOM 7594 C C . ILE B 1 454 ? 2.752 -0.591 28.536 1.00 19.27 ? 454 ILE B C 1 ATOM 7595 O O . ILE B 1 454 ? 3.886 -0.591 29.037 1.00 19.90 ? 454 ILE B O 1 ATOM 7596 C CB . ILE B 1 454 ? 0.759 0.677 29.511 1.00 19.81 ? 454 ILE B CB 1 ATOM 7597 C CG1 . ILE B 1 454 ? -0.066 1.963 29.423 1.00 17.51 ? 454 ILE B CG1 1 ATOM 7598 C CG2 . ILE B 1 454 ? 1.305 0.569 30.952 1.00 20.32 ? 454 ILE B CG2 1 ATOM 7599 C CD1 . ILE B 1 454 ? -1.303 1.929 30.322 1.00 19.03 ? 454 ILE B CD1 1 ATOM 7600 N N . LYS B 1 455 ? 2.179 -1.669 27.996 1.00 18.80 ? 455 LYS B N 1 ATOM 7601 C CA . LYS B 1 455 ? 2.832 -2.974 27.930 1.00 19.30 ? 455 LYS B CA 1 ATOM 7602 C C . LYS B 1 455 ? 4.252 -2.912 27.327 1.00 19.41 ? 455 LYS B C 1 ATOM 7603 O O . LYS B 1 455 ? 5.179 -3.522 27.874 1.00 19.49 ? 455 LYS B O 1 ATOM 7604 C CB . LYS B 1 455 ? 1.980 -3.965 27.140 1.00 19.02 ? 455 LYS B CB 1 ATOM 7605 C CG . LYS B 1 455 ? 2.557 -5.391 27.094 1.00 21.79 ? 455 LYS B CG 1 ATOM 7606 C CD . LYS B 1 455 ? 1.899 -6.269 26.048 1.00 24.47 ? 455 LYS B CD 1 ATOM 7607 C CE . LYS B 1 455 ? 2.446 -7.695 26.173 1.00 25.01 ? 455 LYS B CE 1 ATOM 7608 N NZ . LYS B 1 455 ? 2.127 -8.561 24.993 1.00 28.30 ? 455 LYS B NZ 1 ATOM 7609 N N . TYR B 1 456 ? 4.412 -2.173 26.226 1.00 17.94 ? 456 TYR B N 1 ATOM 7610 C CA . TYR B 1 456 ? 5.653 -2.207 25.459 1.00 17.35 ? 456 TYR B CA 1 ATOM 7611 C C . TYR B 1 456 ? 6.607 -1.102 25.850 1.00 17.21 ? 456 TYR B C 1 ATOM 7612 O O . TYR B 1 456 ? 7.678 -0.984 25.251 1.00 17.11 ? 456 TYR B O 1 ATOM 7613 C CB . TYR B 1 456 ? 5.389 -2.237 23.934 1.00 17.04 ? 456 TYR B CB 1 ATOM 7614 C CG . TYR B 1 456 ? 4.712 -3.506 23.480 1.00 17.18 ? 456 TYR B CG 1 ATOM 7615 C CD1 . TYR B 1 456 ? 5.314 -4.749 23.675 1.00 18.85 ? 456 TYR B CD1 1 ATOM 7616 C CD2 . TYR B 1 456 ? 3.476 -3.466 22.849 1.00 19.79 ? 456 TYR B CD2 1 ATOM 7617 C CE1 . TYR B 1 456 ? 4.700 -5.912 23.269 1.00 17.20 ? 456 TYR B CE1 1 ATOM 7618 C CE2 . TYR B 1 456 ? 2.841 -4.628 22.433 1.00 20.38 ? 456 TYR B CE2 1 ATOM 7619 C CZ . TYR B 1 456 ? 3.462 -5.843 22.643 1.00 20.37 ? 456 TYR B CZ 1 ATOM 7620 O OH . TYR B 1 456 ? 2.833 -6.975 22.236 1.00 22.57 ? 456 TYR B OH 1 ATOM 7621 N N . SER B 1 457 ? 6.238 -0.314 26.866 1.00 16.61 ? 457 SER B N 1 ATOM 7622 C CA . SER B 1 457 ? 7.138 0.694 27.387 1.00 17.76 ? 457 SER B CA 1 ATOM 7623 C C . SER B 1 457 ? 8.308 -0.017 28.112 1.00 17.97 ? 457 SER B C 1 ATOM 7624 O O . SER B 1 457 ? 8.303 -1.247 28.254 1.00 18.63 ? 457 SER B O 1 ATOM 7625 C CB . SER B 1 457 ? 6.399 1.674 28.314 1.00 17.45 ? 457 SER B CB 1 ATOM 7626 O OG . SER B 1 457 ? 6.153 1.073 29.570 1.00 19.18 ? 457 SER B OG 1 ATOM 7627 N N . THR B 1 458 ? 9.304 0.759 28.523 1.00 19.55 ? 458 THR B N 1 ATOM 7628 C CA . THR B 1 458 ? 10.518 0.247 29.201 1.00 20.11 ? 458 THR B CA 1 ATOM 7629 C C . THR B 1 458 ? 10.412 0.410 30.728 1.00 20.80 ? 458 THR B C 1 ATOM 7630 O O . THR B 1 458 ? 11.400 0.295 31.458 1.00 21.07 ? 458 THR B O 1 ATOM 7631 C CB . THR B 1 458 ? 11.802 0.929 28.643 1.00 19.19 ? 458 THR B CB 1 ATOM 7632 O OG1 . THR B 1 458 ? 11.798 2.329 28.941 1.00 21.10 ? 458 THR B OG1 1 ATOM 7633 C CG2 . THR B 1 458 ? 11.858 0.808 27.130 1.00 20.30 ? 458 THR B CG2 1 ATOM 7634 N N . LEU B 1 459 ? 9.211 0.700 31.213 1.00 21.17 ? 459 LEU B N 1 ATOM 7635 C CA . LEU B 1 459 ? 9.013 0.865 32.642 1.00 22.16 ? 459 LEU B CA 1 ATOM 7636 C C . LEU B 1 459 ? 9.165 -0.479 33.375 1.00 23.11 ? 459 LEU B C 1 ATOM 7637 O O . LEU B 1 459 ? 8.987 -1.542 32.767 1.00 22.41 ? 459 LEU B O 1 ATOM 7638 C CB . LEU B 1 459 ? 7.665 1.548 32.940 1.00 20.83 ? 459 LEU B CB 1 ATOM 7639 C CG . LEU B 1 459 ? 7.430 3.007 32.477 1.00 21.14 ? 459 LEU B CG 1 ATOM 7640 C CD1 . LEU B 1 459 ? 5.932 3.351 32.450 1.00 19.06 ? 459 LEU B CD1 1 ATOM 7641 C CD2 . LEU B 1 459 ? 8.166 4.053 33.323 1.00 21.20 ? 459 LEU B CD2 1 ATOM 7642 N N . LEU B 1 460 ? 9.517 -0.434 34.669 1.00 24.31 ? 460 LEU B N 1 ATOM 7643 C CA . LEU B 1 460 ? 9.465 -1.637 35.523 1.00 26.01 ? 460 LEU B CA 1 ATOM 7644 C C . LEU B 1 460 ? 8.047 -2.189 35.512 1.00 26.98 ? 460 LEU B C 1 ATOM 7645 O O . LEU B 1 460 ? 7.093 -1.418 35.391 1.00 27.35 ? 460 LEU B O 1 ATOM 7646 C CB . LEU B 1 460 ? 9.846 -1.296 36.978 1.00 26.30 ? 460 LEU B CB 1 ATOM 7647 C CG . LEU B 1 460 ? 11.222 -0.682 37.262 1.00 27.28 ? 460 LEU B CG 1 ATOM 7648 C CD1 . LEU B 1 460 ? 11.368 -0.311 38.744 1.00 26.94 ? 460 LEU B CD1 1 ATOM 7649 C CD2 . LEU B 1 460 ? 12.352 -1.589 36.792 1.00 27.40 ? 460 LEU B CD2 1 ATOM 7650 N N . GLU B 1 461 ? 7.898 -3.505 35.654 1.00 28.16 ? 461 GLU B N 1 ATOM 7651 C CA . GLU B 1 461 ? 6.570 -4.123 35.716 1.00 29.68 ? 461 GLU B CA 1 ATOM 7652 C C . GLU B 1 461 ? 5.673 -3.524 36.824 1.00 29.72 ? 461 GLU B C 1 ATOM 7653 O O . GLU B 1 461 ? 4.455 -3.350 36.635 1.00 29.42 ? 461 GLU B O 1 ATOM 7654 C CB . GLU B 1 461 ? 6.686 -5.651 35.835 1.00 30.87 ? 461 GLU B CB 1 ATOM 7655 C CG . GLU B 1 461 ? 7.360 -6.316 34.616 1.00 33.45 ? 461 GLU B CG 1 ATOM 7656 C CD . GLU B 1 461 ? 6.623 -6.048 33.295 1.00 37.44 ? 461 GLU B CD 1 ATOM 7657 O OE1 . GLU B 1 461 ? 5.376 -6.126 33.270 1.00 40.74 ? 461 GLU B OE1 1 ATOM 7658 O OE2 . GLU B 1 461 ? 7.290 -5.765 32.274 1.00 38.87 ? 461 GLU B OE2 1 ATOM 7659 N N . SER B 1 462 ? 6.288 -3.151 37.944 1.00 29.39 ? 462 SER B N 1 ATOM 7660 C CA . SER B 1 462 ? 5.547 -2.539 39.043 1.00 29.30 ? 462 SER B CA 1 ATOM 7661 C C . SER B 1 462 ? 5.060 -1.129 38.673 1.00 28.85 ? 462 SER B C 1 ATOM 7662 O O . SER B 1 462 ? 3.992 -0.706 39.109 1.00 28.84 ? 462 SER B O 1 ATOM 7663 C CB . SER B 1 462 ? 6.398 -2.498 40.311 1.00 29.59 ? 462 SER B CB 1 ATOM 7664 O OG . SER B 1 462 ? 7.362 -1.455 40.263 1.00 31.31 ? 462 SER B OG 1 ATOM 7665 N N . GLU B 1 463 ? 5.852 -0.416 37.871 1.00 27.91 ? 463 GLU B N 1 ATOM 7666 C CA . GLU B 1 463 ? 5.472 0.900 37.341 1.00 26.94 ? 463 GLU B CA 1 ATOM 7667 C C . GLU B 1 463 ? 4.390 0.830 36.261 1.00 25.63 ? 463 GLU B C 1 ATOM 7668 O O . GLU B 1 463 ? 3.526 1.704 36.202 1.00 25.01 ? 463 GLU B O 1 ATOM 7669 C CB . GLU B 1 463 ? 6.706 1.635 36.810 1.00 27.23 ? 463 GLU B CB 1 ATOM 7670 C CG . GLU B 1 463 ? 7.768 1.873 37.881 1.00 29.17 ? 463 GLU B CG 1 ATOM 7671 C CD . GLU B 1 463 ? 9.138 2.278 37.317 1.00 33.05 ? 463 GLU B CD 1 ATOM 7672 O OE1 . GLU B 1 463 ? 9.486 1.927 36.156 1.00 32.20 ? 463 GLU B OE1 1 ATOM 7673 O OE2 . GLU B 1 463 ? 9.874 2.959 38.056 1.00 34.88 ? 463 GLU B OE2 1 ATOM 7674 N N . LYS B 1 464 ? 4.449 -0.193 35.410 1.00 25.13 ? 464 LYS B N 1 ATOM 7675 C CA . LYS B 1 464 ? 3.411 -0.445 34.396 1.00 24.89 ? 464 LYS B CA 1 ATOM 7676 C C . LYS B 1 464 ? 2.059 -0.743 35.058 1.00 25.72 ? 464 LYS B C 1 ATOM 7677 O O . LYS B 1 464 ? 1.008 -0.228 34.635 1.00 24.91 ? 464 LYS B O 1 ATOM 7678 C CB . LYS B 1 464 ? 3.814 -1.592 33.486 1.00 24.56 ? 464 LYS B CB 1 ATOM 7679 C CG . LYS B 1 464 ? 4.997 -1.288 32.547 1.00 22.39 ? 464 LYS B CG 1 ATOM 7680 C CD . LYS B 1 464 ? 5.299 -2.530 31.762 1.00 21.28 ? 464 LYS B CD 1 ATOM 7681 C CE . LYS B 1 464 ? 6.553 -2.386 30.951 1.00 23.42 ? 464 LYS B CE 1 ATOM 7682 N NZ . LYS B 1 464 ? 6.863 -3.652 30.211 1.00 21.74 ? 464 LYS B NZ 1 ATOM 7683 N N . ASN B 1 465 ? 2.104 -1.559 36.110 1.00 26.64 ? 465 ASN B N 1 ATOM 7684 C CA . ASN B 1 465 ? 0.966 -1.784 37.015 1.00 27.19 ? 465 ASN B CA 1 ATOM 7685 C C . ASN B 1 465 ? 0.302 -0.513 37.561 1.00 26.81 ? 465 ASN B C 1 ATOM 7686 O O . ASN B 1 465 ? -0.927 -0.372 37.494 1.00 26.77 ? 465 ASN B O 1 ATOM 7687 C CB . ASN B 1 465 ? 1.418 -2.670 38.175 1.00 28.28 ? 465 ASN B CB 1 ATOM 7688 C CG . ASN B 1 465 ? 1.529 -4.112 37.784 1.00 31.37 ? 465 ASN B CG 1 ATOM 7689 O OD1 . ASN B 1 465 ? 1.066 -4.525 36.718 1.00 37.58 ? 465 ASN B OD1 1 ATOM 7690 N ND2 . ASN B 1 465 ? 2.155 -4.901 38.638 1.00 36.54 ? 465 ASN B ND2 1 ATOM 7691 N N . THR B 1 466 ? 1.108 0.412 38.082 1.00 26.52 ? 466 THR B N 1 ATOM 7692 C CA . THR B 1 466 ? 0.621 1.729 38.546 1.00 26.78 ? 466 THR B CA 1 ATOM 7693 C C . THR B 1 466 ? 0.074 2.608 37.404 1.00 26.12 ? 466 THR B C 1 ATOM 7694 O O . THR B 1 466 ? -0.964 3.286 37.536 1.00 25.71 ? 466 THR B O 1 ATOM 7695 C CB . THR B 1 466 ? 1.763 2.527 39.266 1.00 27.07 ? 466 THR B CB 1 ATOM 7696 O OG1 . THR B 1 466 ? 2.341 1.728 40.304 1.00 29.64 ? 466 THR B OG1 1 ATOM 7697 C CG2 . THR B 1 466 ? 1.236 3.799 39.881 1.00 26.69 ? 466 THR B CG2 1 ATOM 7698 N N . PHE B 1 467 ? 0.813 2.625 36.298 1.00 25.05 ? 467 PHE B N 1 ATOM 7699 C CA . PHE B 1 467 ? 0.397 3.325 35.082 1.00 24.67 ? 467 PHE B CA 1 ATOM 7700 C C . PHE B 1 467 ? -0.964 2.767 34.641 1.00 24.41 ? 467 PHE B C 1 ATOM 7701 O O . PHE B 1 467 ? -1.898 3.527 34.427 1.00 23.78 ? 467 PHE B O 1 ATOM 7702 C CB . PHE B 1 467 ? 1.454 3.096 33.992 1.00 24.10 ? 467 PHE B CB 1 ATOM 7703 C CG . PHE B 1 467 ? 1.348 4.006 32.796 1.00 23.75 ? 467 PHE B CG 1 ATOM 7704 C CD1 . PHE B 1 467 ? 0.225 4.793 32.561 1.00 22.43 ? 467 PHE B CD1 1 ATOM 7705 C CD2 . PHE B 1 467 ? 2.383 4.014 31.852 1.00 22.40 ? 467 PHE B CD2 1 ATOM 7706 C CE1 . PHE B 1 467 ? 0.153 5.619 31.415 1.00 24.20 ? 467 PHE B CE1 1 ATOM 7707 C CE2 . PHE B 1 467 ? 2.316 4.831 30.720 1.00 23.59 ? 467 PHE B CE2 1 ATOM 7708 C CZ . PHE B 1 467 ? 1.209 5.629 30.498 1.00 22.23 ? 467 PHE B CZ 1 ATOM 7709 N N . MET B 1 468 ? -1.073 1.448 34.544 1.00 24.49 ? 468 MET B N 1 ATOM 7710 C CA . MET B 1 468 ? -2.328 0.813 34.164 1.00 26.17 ? 468 MET B CA 1 ATOM 7711 C C . MET B 1 468 ? -3.502 1.243 35.074 1.00 25.94 ? 468 MET B C 1 ATOM 7712 O O . MET B 1 468 ? -4.611 1.517 34.576 1.00 24.73 ? 468 MET B O 1 ATOM 7713 C CB . MET B 1 468 ? -2.179 -0.704 34.094 1.00 26.48 ? 468 MET B CB 1 ATOM 7714 C CG . MET B 1 468 ? -3.346 -1.411 33.423 1.00 31.72 ? 468 MET B CG 1 ATOM 7715 S SD . MET B 1 468 ? -3.487 -1.027 31.657 1.00 37.68 ? 468 MET B SD 1 ATOM 7716 C CE . MET B 1 468 ? -1.949 -1.701 31.031 1.00 32.34 ? 468 MET B CE 1 ATOM 7717 N N . GLU B 1 469 ? -3.239 1.363 36.383 1.00 25.61 ? 469 GLU B N 1 ATOM 7718 C CA . GLU B 1 469 ? -4.284 1.799 37.337 1.00 26.17 ? 469 GLU B CA 1 ATOM 7719 C C . GLU B 1 469 ? -4.766 3.221 37.083 1.00 25.30 ? 469 GLU B C 1 ATOM 7720 O O . GLU B 1 469 ? -5.977 3.486 37.099 1.00 24.10 ? 469 GLU B O 1 ATOM 7721 C CB . GLU B 1 469 ? -3.831 1.650 38.787 1.00 26.05 ? 469 GLU B CB 1 ATOM 7722 C CG . GLU B 1 469 ? -3.586 0.240 39.167 1.00 30.51 ? 469 GLU B CG 1 ATOM 7723 C CD . GLU B 1 469 ? -2.991 0.078 40.552 1.00 37.72 ? 469 GLU B CD 1 ATOM 7724 O OE1 . GLU B 1 469 ? -2.485 1.068 41.143 1.00 40.20 ? 469 GLU B OE1 1 ATOM 7725 O OE2 . GLU B 1 469 ? -3.027 -1.068 41.059 1.00 42.62 ? 469 GLU B OE2 1 ATOM 7726 N N . ILE B 1 470 ? -3.813 4.126 36.855 1.00 24.55 ? 470 ILE B N 1 ATOM 7727 C CA . ILE B 1 470 ? -4.104 5.512 36.506 1.00 24.14 ? 470 ILE B CA 1 ATOM 7728 C C . ILE B 1 470 ? -4.831 5.578 35.153 1.00 24.03 ? 470 ILE B C 1 ATOM 7729 O O . ILE B 1 470 ? -5.840 6.307 34.994 1.00 23.67 ? 470 ILE B O 1 ATOM 7730 C CB . ILE B 1 470 ? -2.813 6.366 36.424 1.00 24.33 ? 470 ILE B CB 1 ATOM 7731 C CG1 . ILE B 1 470 ? -2.143 6.502 37.802 1.00 24.60 ? 470 ILE B CG1 1 ATOM 7732 C CG2 . ILE B 1 470 ? -3.116 7.752 35.818 1.00 24.13 ? 470 ILE B CG2 1 ATOM 7733 C CD1 . ILE B 1 470 ? -0.700 7.060 37.742 1.00 24.13 ? 470 ILE B CD1 1 ATOM 7734 N N . TRP B 1 471 ? -4.321 4.821 34.183 1.00 23.25 ? 471 TRP B N 1 ATOM 7735 C CA . TRP B 1 471 ? -4.953 4.802 32.867 1.00 23.82 ? 471 TRP B CA 1 ATOM 7736 C C . TRP B 1 471 ? -6.409 4.299 32.947 1.00 24.05 ? 471 TRP B C 1 ATOM 7737 O O . TRP B 1 471 ? -7.292 4.912 32.353 1.00 23.98 ? 471 TRP B O 1 ATOM 7738 C CB . TRP B 1 471 ? -4.137 4.015 31.832 1.00 22.60 ? 471 TRP B CB 1 ATOM 7739 C CG . TRP B 1 471 ? -4.873 3.828 30.515 1.00 22.38 ? 471 TRP B CG 1 ATOM 7740 C CD1 . TRP B 1 471 ? -4.914 4.701 29.446 1.00 22.84 ? 471 TRP B CD1 1 ATOM 7741 C CD2 . TRP B 1 471 ? -5.696 2.724 30.160 1.00 22.67 ? 471 TRP B CD2 1 ATOM 7742 N NE1 . TRP B 1 471 ? -5.698 4.182 28.429 1.00 21.23 ? 471 TRP B NE1 1 ATOM 7743 C CE2 . TRP B 1 471 ? -6.181 2.963 28.840 1.00 24.64 ? 471 TRP B CE2 1 ATOM 7744 C CE3 . TRP B 1 471 ? -6.055 1.537 30.811 1.00 22.28 ? 471 TRP B CE3 1 ATOM 7745 C CZ2 . TRP B 1 471 ? -7.025 2.062 28.179 1.00 22.44 ? 471 TRP B CZ2 1 ATOM 7746 C CZ3 . TRP B 1 471 ? -6.871 0.642 30.158 1.00 22.53 ? 471 TRP B CZ3 1 ATOM 7747 C CH2 . TRP B 1 471 ? -7.368 0.916 28.851 1.00 23.57 ? 471 TRP B CH2 1 ATOM 7748 N N . LYS B 1 472 ? -6.636 3.195 33.658 1.00 24.64 ? 472 LYS B N 1 ATOM 7749 C CA . LYS B 1 472 ? -7.978 2.580 33.747 1.00 26.16 ? 472 LYS B CA 1 ATOM 7750 C C . LYS B 1 472 ? -9.052 3.544 34.297 1.00 25.96 ? 472 LYS B C 1 ATOM 7751 O O . LYS B 1 472 ? -10.188 3.558 33.801 1.00 25.83 ? 472 LYS B O 1 ATOM 7752 C CB . LYS B 1 472 ? -7.936 1.252 34.534 1.00 26.35 ? 472 LYS B CB 1 ATOM 7753 C CG . LYS B 1 472 ? -9.297 0.539 34.727 1.00 30.68 ? 472 LYS B CG 1 ATOM 7754 C CD . LYS B 1 472 ? -9.795 -0.131 33.434 1.00 36.45 ? 472 LYS B CD 1 ATOM 7755 C CE . LYS B 1 472 ? -11.085 -0.944 33.657 1.00 38.95 ? 472 LYS B CE 1 ATOM 7756 N NZ . LYS B 1 472 ? -12.336 -0.116 33.589 1.00 39.53 ? 472 LYS B NZ 1 ATOM 7757 N N . LYS B 1 473 ? -8.681 4.349 35.293 1.00 25.76 ? 473 LYS B N 1 ATOM 7758 C CA . LYS B 1 473 ? -9.554 5.397 35.834 1.00 26.26 ? 473 LYS B CA 1 ATOM 7759 C C . LYS B 1 473 ? -9.899 6.440 34.785 1.00 26.04 ? 473 LYS B C 1 ATOM 7760 O O . LYS B 1 473 ? -11.057 6.891 34.694 1.00 24.95 ? 473 LYS B O 1 ATOM 7761 C CB . LYS B 1 473 ? -8.906 6.124 37.026 1.00 26.14 ? 473 LYS B CB 1 ATOM 7762 C CG . LYS B 1 473 ? -8.931 5.349 38.303 1.00 29.57 ? 473 LYS B CG 1 ATOM 7763 C CD . LYS B 1 473 ? -8.485 6.213 39.484 1.00 34.03 ? 473 LYS B CD 1 ATOM 7764 C CE . LYS B 1 473 ? -8.620 5.444 40.792 1.00 36.92 ? 473 LYS B CE 1 ATOM 7765 N NZ . LYS B 1 473 ? -8.006 4.069 40.704 1.00 39.12 ? 473 LYS B NZ 1 ATOM 7766 N N . ARG B 1 474 ? -8.899 6.848 34.002 1.00 24.75 ? 474 ARG B N 1 ATOM 7767 C CA . ARG B 1 474 ? -9.167 7.828 32.939 1.00 24.17 ? 474 ARG B CA 1 ATOM 7768 C C . ARG B 1 474 ? -10.020 7.200 31.819 1.00 23.04 ? 474 ARG B C 1 ATOM 7769 O O . ARG B 1 474 ? -10.888 7.868 31.241 1.00 23.14 ? 474 ARG B O 1 ATOM 7770 C CB . ARG B 1 474 ? -7.865 8.430 32.391 1.00 24.20 ? 474 ARG B CB 1 ATOM 7771 C CG . ARG B 1 474 ? -7.172 9.375 33.389 1.00 25.91 ? 474 ARG B CG 1 ATOM 7772 C CD . ARG B 1 474 ? -6.356 10.437 32.668 1.00 30.13 ? 474 ARG B CD 1 ATOM 7773 N NE . ARG B 1 474 ? -5.926 11.500 33.570 1.00 31.82 ? 474 ARG B NE 1 ATOM 7774 C CZ . ARG B 1 474 ? -5.482 12.688 33.173 1.00 31.25 ? 474 ARG B CZ 1 ATOM 7775 N NH1 . ARG B 1 474 ? -5.381 12.975 31.881 1.00 28.71 ? 474 ARG B NH1 1 ATOM 7776 N NH2 . ARG B 1 474 ? -5.127 13.591 34.080 1.00 30.79 ? 474 ARG B NH2 1 ATOM 7777 N N . TRP B 1 475 ? -9.793 5.917 31.558 1.00 22.35 ? 475 TRP B N 1 ATOM 7778 C CA . TRP B 1 475 ? -10.556 5.188 30.539 1.00 23.53 ? 475 TRP B CA 1 ATOM 7779 C C . TRP B 1 475 ? -12.054 5.148 30.933 1.00 23.97 ? 475 TRP B C 1 ATOM 7780 O O . TRP B 1 475 ? -12.932 5.580 30.165 1.00 24.17 ? 475 TRP B O 1 ATOM 7781 C CB . TRP B 1 475 ? -9.951 3.795 30.270 1.00 22.67 ? 475 TRP B CB 1 ATOM 7782 C CG . TRP B 1 475 ? -10.722 2.948 29.268 1.00 22.48 ? 475 TRP B CG 1 ATOM 7783 C CD1 . TRP B 1 475 ? -11.638 1.967 29.556 1.00 21.34 ? 475 TRP B CD1 1 ATOM 7784 C CD2 . TRP B 1 475 ? -10.642 3.010 27.828 1.00 20.07 ? 475 TRP B CD2 1 ATOM 7785 N NE1 . TRP B 1 475 ? -12.147 1.430 28.378 1.00 20.37 ? 475 TRP B NE1 1 ATOM 7786 C CE2 . TRP B 1 475 ? -11.553 2.050 27.312 1.00 18.74 ? 475 TRP B CE2 1 ATOM 7787 C CE3 . TRP B 1 475 ? -9.894 3.790 26.928 1.00 18.64 ? 475 TRP B CE3 1 ATOM 7788 C CZ2 . TRP B 1 475 ? -11.730 1.841 25.937 1.00 19.23 ? 475 TRP B CZ2 1 ATOM 7789 C CZ3 . TRP B 1 475 ? -10.071 3.586 25.558 1.00 17.37 ? 475 TRP B CZ3 1 ATOM 7790 C CH2 . TRP B 1 475 ? -10.984 2.616 25.076 1.00 17.83 ? 475 TRP B CH2 1 ATOM 7791 N N . ASP B 1 476 ? -12.327 4.694 32.149 1.00 24.54 ? 476 ASP B N 1 ATOM 7792 C CA . ASP B 1 476 ? -13.708 4.635 32.656 1.00 25.23 ? 476 ASP B CA 1 ATOM 7793 C C . ASP B 1 476 ? -14.470 5.940 32.578 1.00 24.91 ? 476 ASP B C 1 ATOM 7794 O O . ASP B 1 476 ? -15.644 5.935 32.194 1.00 26.14 ? 476 ASP B O 1 ATOM 7795 C CB . ASP B 1 476 ? -13.726 4.075 34.074 1.00 25.29 ? 476 ASP B CB 1 ATOM 7796 C CG . ASP B 1 476 ? -13.290 2.653 34.102 1.00 26.90 ? 476 ASP B CG 1 ATOM 7797 O OD1 . ASP B 1 476 ? -13.281 2.052 33.016 1.00 29.39 ? 476 ASP B OD1 1 ATOM 7798 O OD2 . ASP B 1 476 ? -12.936 2.125 35.171 1.00 29.04 ? 476 ASP B OD2 1 ATOM 7799 N N . LYS B 1 477 ? -13.819 7.043 32.941 1.00 24.81 ? 477 LYS B N 1 ATOM 7800 C CA . LYS B 1 477 ? -14.396 8.399 32.804 1.00 25.52 ? 477 LYS B CA 1 ATOM 7801 C C . LYS B 1 477 ? -14.675 8.786 31.342 1.00 24.60 ? 477 LYS B C 1 ATOM 7802 O O . LYS B 1 477 ? -15.677 9.472 31.018 1.00 25.30 ? 477 LYS B O 1 ATOM 7803 C CB . LYS B 1 477 ? -13.487 9.433 33.509 1.00 25.79 ? 477 LYS B CB 1 ATOM 7804 C CG . LYS B 1 477 ? -13.661 10.912 33.105 1.00 27.70 ? 477 LYS B CG 1 ATOM 7805 C CD . LYS B 1 477 ? -12.670 11.781 33.920 1.00 35.26 ? 477 LYS B CD 1 ATOM 7806 C CE . LYS B 1 477 ? -12.811 13.292 33.655 1.00 38.65 ? 477 LYS B CE 1 ATOM 7807 N NZ . LYS B 1 477 ? -11.830 13.789 32.656 1.00 40.17 ? 477 LYS B NZ 1 ATOM 7808 N N . PHE B 1 478 ? -13.772 8.364 30.469 1.00 23.51 ? 478 PHE B N 1 ATOM 7809 C CA . PHE B 1 478 ? -13.888 8.608 29.041 1.00 22.35 ? 478 PHE B CA 1 ATOM 7810 C C . PHE B 1 478 ? -15.100 7.831 28.500 1.00 22.35 ? 478 PHE B C 1 ATOM 7811 O O . PHE B 1 478 ? -15.933 8.395 27.806 1.00 22.43 ? 478 PHE B O 1 ATOM 7812 C CB . PHE B 1 478 ? -12.567 8.213 28.357 1.00 21.60 ? 478 PHE B CB 1 ATOM 7813 C CG . PHE B 1 478 ? -12.694 7.919 26.891 1.00 19.48 ? 478 PHE B CG 1 ATOM 7814 C CD1 . PHE B 1 478 ? -12.833 8.951 25.966 1.00 18.46 ? 478 PHE B CD1 1 ATOM 7815 C CD2 . PHE B 1 478 ? -12.657 6.606 26.438 1.00 17.77 ? 478 PHE B CD2 1 ATOM 7816 C CE1 . PHE B 1 478 ? -12.936 8.666 24.587 1.00 19.16 ? 478 PHE B CE1 1 ATOM 7817 C CE2 . PHE B 1 478 ? -12.757 6.303 25.061 1.00 19.17 ? 478 PHE B CE2 1 ATOM 7818 C CZ . PHE B 1 478 ? -12.904 7.338 24.139 1.00 16.82 ? 478 PHE B CZ 1 ATOM 7819 N N . ILE B 1 479 ? -15.204 6.556 28.871 1.00 23.39 ? 479 ILE B N 1 ATOM 7820 C CA . ILE B 1 479 ? -16.318 5.705 28.489 1.00 24.52 ? 479 ILE B CA 1 ATOM 7821 C C . ILE B 1 479 ? -17.656 6.317 28.958 1.00 25.42 ? 479 ILE B C 1 ATOM 7822 O O . ILE B 1 479 ? -18.610 6.375 28.191 1.00 24.66 ? 479 ILE B O 1 ATOM 7823 C CB . ILE B 1 479 ? -16.145 4.255 29.037 1.00 24.95 ? 479 ILE B CB 1 ATOM 7824 C CG1 . ILE B 1 479 ? -14.949 3.540 28.377 1.00 24.41 ? 479 ILE B CG1 1 ATOM 7825 C CG2 . ILE B 1 479 ? -17.437 3.432 28.875 1.00 25.77 ? 479 ILE B CG2 1 ATOM 7826 C CD1 . ILE B 1 479 ? -15.048 3.308 26.845 1.00 26.99 ? 479 ILE B CD1 1 ATOM 7827 N N . ALA B 1 480 ? -17.699 6.804 30.199 1.00 25.81 ? 480 ALA B N 1 ATOM 7828 C CA . ALA B 1 480 ? -18.918 7.389 30.725 1.00 27.71 ? 480 ALA B CA 1 ATOM 7829 C C . ALA B 1 480 ? -19.309 8.614 29.911 1.00 28.19 ? 480 ALA B C 1 ATOM 7830 O O . ALA B 1 480 ? -20.496 8.800 29.618 1.00 28.33 ? 480 ALA B O 1 ATOM 7831 C CB . ALA B 1 480 ? -18.792 7.733 32.234 1.00 27.50 ? 480 ALA B CB 1 ATOM 7832 N N . ASP B 1 481 ? -18.321 9.424 29.523 1.00 28.65 ? 481 ASP B N 1 ATOM 7833 C CA . ASP B 1 481 ? -18.598 10.634 28.735 1.00 29.69 ? 481 ASP B CA 1 ATOM 7834 C C . ASP B 1 481 ? -19.165 10.293 27.370 1.00 29.97 ? 481 ASP B C 1 ATOM 7835 O O . ASP B 1 481 ? -20.230 10.792 27.008 1.00 30.27 ? 481 ASP B O 1 ATOM 7836 C CB . ASP B 1 481 ? -17.362 11.514 28.578 1.00 30.20 ? 481 ASP B CB 1 ATOM 7837 C CG . ASP B 1 481 ? -16.998 12.247 29.857 1.00 33.26 ? 481 ASP B CG 1 ATOM 7838 O OD1 . ASP B 1 481 ? -17.908 12.587 30.647 1.00 36.09 ? 481 ASP B OD1 1 ATOM 7839 O OD2 . ASP B 1 481 ? -15.796 12.491 30.071 1.00 36.32 ? 481 ASP B OD2 1 ATOM 7840 N N . VAL B 1 482 ? -18.457 9.439 26.628 1.00 29.91 ? 482 VAL B N 1 ATOM 7841 C CA . VAL B 1 482 ? -18.896 8.984 25.300 1.00 29.98 ? 482 VAL B CA 1 ATOM 7842 C C . VAL B 1 482 ? -20.284 8.312 25.334 1.00 30.85 ? 482 VAL B C 1 ATOM 7843 O O . VAL B 1 482 ? -21.089 8.555 24.456 1.00 30.12 ? 482 VAL B O 1 ATOM 7844 C CB . VAL B 1 482 ? -17.867 8.026 24.648 1.00 29.76 ? 482 VAL B CB 1 ATOM 7845 C CG1 . VAL B 1 482 ? -18.377 7.515 23.271 1.00 29.99 ? 482 VAL B CG1 1 ATOM 7846 C CG2 . VAL B 1 482 ? -16.515 8.720 24.501 1.00 28.73 ? 482 VAL B CG2 1 ATOM 7847 N N . ALA B 1 483 ? -20.538 7.457 26.332 1.00 31.89 ? 483 ALA B N 1 ATOM 7848 C CA . ALA B 1 483 ? -21.817 6.749 26.435 1.00 33.64 ? 483 ALA B CA 1 ATOM 7849 C C . ALA B 1 483 ? -22.967 7.715 26.728 1.00 34.87 ? 483 ALA B C 1 ATOM 7850 O O . ALA B 1 483 ? -24.084 7.522 26.234 1.00 36.09 ? 483 ALA B O 1 ATOM 7851 C CB . ALA B 1 483 ? -21.756 5.622 27.473 1.00 32.63 ? 483 ALA B CB 1 ATOM 7852 N N . THR B 1 484 ? -22.683 8.751 27.512 1.00 36.08 ? 484 THR B N 1 ATOM 7853 C CA . THR B 1 484 ? -23.600 9.879 27.721 1.00 37.31 ? 484 THR B CA 1 ATOM 7854 C C . THR B 1 484 ? -23.292 10.971 26.700 1.00 37.17 ? 484 THR B C 1 ATOM 7855 O O . THR B 1 484 ? -23.201 12.162 27.018 1.00 37.17 ? 484 THR B O 1 ATOM 7856 C CB . THR B 1 484 ? -23.478 10.464 29.149 1.00 37.47 ? 484 THR B CB 1 ATOM 7857 O OG1 . THR B 1 484 ? -23.463 9.397 30.108 1.00 38.56 ? 484 THR B OG1 1 ATOM 7858 C CG2 . THR B 1 484 ? -24.665 11.395 29.442 1.00 39.41 ? 484 THR B CG2 1 HETATM 7859 C C1 . NAG C 2 . ? -6.919 -1.932 -42.516 1.00 48.16 ? 550 NAG A C1 1 HETATM 7860 C C2 . NAG C 2 . ? -5.881 -1.963 -43.634 1.00 51.61 ? 550 NAG A C2 1 HETATM 7861 C C3 . NAG C 2 . ? -5.904 -3.266 -44.445 1.00 52.80 ? 550 NAG A C3 1 HETATM 7862 C C4 . NAG C 2 . ? -6.808 -4.404 -43.926 1.00 53.26 ? 550 NAG A C4 1 HETATM 7863 C C5 . NAG C 2 . ? -7.390 -4.248 -42.513 1.00 52.45 ? 550 NAG A C5 1 HETATM 7864 C C6 . NAG C 2 . ? -7.139 -5.499 -41.685 1.00 52.54 ? 550 NAG A C6 1 HETATM 7865 C C7 . NAG C 2 . ? -5.060 -0.024 -44.858 1.00 52.82 ? 550 NAG A C7 1 HETATM 7866 C C8 . NAG C 2 . ? -5.356 1.118 -45.788 1.00 52.81 ? 550 NAG A C8 1 HETATM 7867 N N2 . NAG C 2 . ? -6.071 -0.830 -44.531 1.00 52.27 ? 550 NAG A N2 1 HETATM 7868 O O3 . NAG C 2 . ? -4.581 -3.745 -44.584 1.00 53.84 ? 550 NAG A O3 1 HETATM 7869 O O4 . NAG C 2 . ? -7.877 -4.555 -44.841 1.00 54.32 ? 550 NAG A O4 1 HETATM 7870 O O5 . NAG C 2 . ? -6.834 -3.153 -41.814 1.00 51.08 ? 550 NAG A O5 1 HETATM 7871 O O6 . NAG C 2 . ? -7.783 -5.334 -40.443 1.00 52.38 ? 550 NAG A O6 1 HETATM 7872 O O7 . NAG C 2 . ? -3.918 -0.179 -44.428 1.00 53.18 ? 550 NAG A O7 1 HETATM 7873 C C1 . NAG D 2 . ? -11.451 14.810 -28.833 1.00 44.73 ? 650 NAG A C1 1 HETATM 7874 C C2 . NAG D 2 . ? -10.497 15.765 -28.101 1.00 47.85 ? 650 NAG A C2 1 HETATM 7875 C C3 . NAG D 2 . ? -10.925 17.236 -28.244 1.00 49.02 ? 650 NAG A C3 1 HETATM 7876 C C4 . NAG D 2 . ? -11.519 17.603 -29.614 1.00 48.91 ? 650 NAG A C4 1 HETATM 7877 C C5 . NAG D 2 . ? -12.403 16.503 -30.215 1.00 47.71 ? 650 NAG A C5 1 HETATM 7878 C C6 . NAG D 2 . ? -12.771 16.783 -31.675 1.00 47.51 ? 650 NAG A C6 1 HETATM 7879 C C7 . NAG D 2 . ? -9.331 15.296 -25.981 1.00 48.71 ? 650 NAG A C7 1 HETATM 7880 C C8 . NAG D 2 . ? -9.466 14.952 -24.531 1.00 48.22 ? 650 NAG A C8 1 HETATM 7881 N N2 . NAG D 2 . ? -10.458 15.423 -26.685 1.00 48.99 ? 650 NAG A N2 1 HETATM 7882 O O3 . NAG D 2 . ? -9.820 18.077 -27.978 1.00 49.58 ? 650 NAG A O3 1 HETATM 7883 O O4 . NAG D 2 . ? -12.285 18.785 -29.465 1.00 51.85 ? 650 NAG A O4 1 HETATM 7884 O O5 . NAG D 2 . ? -11.744 15.257 -30.147 1.00 45.64 ? 650 NAG A O5 1 HETATM 7885 O O6 . NAG D 2 . ? -11.625 17.131 -32.427 1.00 48.61 ? 650 NAG A O6 1 HETATM 7886 O O7 . NAG D 2 . ? -8.219 15.457 -26.467 1.00 49.75 ? 650 NAG A O7 1 HETATM 7887 C C1 . NAG E 2 . ? -21.122 -24.242 -4.709 1.00 41.52 ? 750 NAG A C1 1 HETATM 7888 C C2 . NAG E 2 . ? -22.564 -24.152 -5.201 1.00 42.90 ? 750 NAG A C2 1 HETATM 7889 C C3 . NAG E 2 . ? -23.528 -24.751 -4.177 1.00 44.96 ? 750 NAG A C3 1 HETATM 7890 C C4 . NAG E 2 . ? -23.072 -26.111 -3.646 1.00 45.86 ? 750 NAG A C4 1 HETATM 7891 C C5 . NAG E 2 . ? -21.571 -26.098 -3.299 1.00 46.04 ? 750 NAG A C5 1 HETATM 7892 C C6 . NAG E 2 . ? -21.070 -27.493 -2.966 1.00 46.65 ? 750 NAG A C6 1 HETATM 7893 C C7 . NAG E 2 . ? -23.145 -22.258 -6.662 1.00 42.62 ? 750 NAG A C7 1 HETATM 7894 C C8 . NAG E 2 . ? -23.589 -20.829 -6.674 1.00 41.42 ? 750 NAG A C8 1 HETATM 7895 N N2 . NAG E 2 . ? -22.978 -22.784 -5.445 1.00 41.64 ? 750 NAG A N2 1 HETATM 7896 O O3 . NAG E 2 . ? -24.798 -24.873 -4.777 1.00 44.98 ? 750 NAG A O3 1 HETATM 7897 O O4 . NAG E 2 . ? -23.863 -26.440 -2.522 1.00 47.02 ? 750 NAG A O4 1 HETATM 7898 O O5 . NAG E 2 . ? -20.807 -25.594 -4.396 1.00 43.90 ? 750 NAG A O5 1 HETATM 7899 O O6 . NAG E 2 . ? -21.299 -28.293 -4.106 1.00 49.26 ? 750 NAG A O6 1 HETATM 7900 O O7 . NAG E 2 . ? -22.953 -22.851 -7.733 1.00 41.83 ? 750 NAG A O7 1 HETATM 7901 ZN ZN . ZN F 3 . ? -11.410 -6.194 -15.500 1.00 30.71 ? 850 ZN A ZN 1 HETATM 7902 C C1 . EDO G 4 . ? -23.192 7.981 -46.837 1.00 22.59 ? 950 EDO A C1 1 HETATM 7903 O O1 . EDO G 4 . ? -24.217 7.396 -46.078 1.00 27.51 ? 950 EDO A O1 1 HETATM 7904 C C2 . EDO G 4 . ? -22.055 7.017 -46.660 1.00 27.88 ? 950 EDO A C2 1 HETATM 7905 O O2 . EDO G 4 . ? -22.515 5.784 -47.169 1.00 25.84 ? 950 EDO A O2 1 HETATM 7906 X UNK . UNX H 5 . ? -11.964 -3.343 -14.576 1.00 25.01 ? 951 UNX A UNK 1 HETATM 7907 C C1 . NAG I 2 . ? 6.353 32.069 26.967 1.00 43.46 ? 550 NAG B C1 1 HETATM 7908 C C2 . NAG I 2 . ? 5.668 33.104 27.866 1.00 45.79 ? 550 NAG B C2 1 HETATM 7909 C C3 . NAG I 2 . ? 5.989 32.900 29.347 1.00 45.90 ? 550 NAG B C3 1 HETATM 7910 C C4 . NAG I 2 . ? 6.142 31.415 29.671 1.00 46.37 ? 550 NAG B C4 1 HETATM 7911 C C5 . NAG I 2 . ? 7.213 30.739 28.795 1.00 46.06 ? 550 NAG B C5 1 HETATM 7912 C C6 . NAG I 2 . ? 6.793 29.305 28.511 1.00 45.86 ? 550 NAG B C6 1 HETATM 7913 C C7 . NAG I 2 . ? 5.089 35.299 26.920 1.00 47.44 ? 550 NAG B C7 1 HETATM 7914 C C8 . NAG I 2 . ? 5.588 36.640 26.452 1.00 47.66 ? 550 NAG B C8 1 HETATM 7915 N N2 . NAG I 2 . ? 6.005 34.438 27.393 1.00 46.63 ? 550 NAG B N2 1 HETATM 7916 O O3 . NAG I 2 . ? 4.932 33.418 30.117 1.00 45.90 ? 550 NAG B O3 1 HETATM 7917 O O4 . NAG I 2 . ? 6.428 31.219 31.045 1.00 48.45 ? 550 NAG B O4 1 HETATM 7918 O O5 . NAG I 2 . ? 7.467 31.435 27.573 1.00 44.91 ? 550 NAG B O5 1 HETATM 7919 O O6 . NAG I 2 . ? 7.929 28.538 28.215 1.00 46.41 ? 550 NAG B O6 1 HETATM 7920 O O7 . NAG I 2 . ? 3.885 35.050 26.849 1.00 47.60 ? 550 NAG B O7 1 HETATM 7921 C C1 . NAG J 2 . ? 12.926 27.641 4.343 1.00 44.33 ? 650 NAG B C1 1 HETATM 7922 C C2 . NAG J 2 . ? 12.311 26.595 3.384 1.00 45.33 ? 650 NAG B C2 1 HETATM 7923 C C3 . NAG J 2 . ? 13.255 26.190 2.244 1.00 46.85 ? 650 NAG B C3 1 HETATM 7924 C C4 . NAG J 2 . ? 13.906 27.445 1.645 1.00 47.67 ? 650 NAG B C4 1 HETATM 7925 C C5 . NAG J 2 . ? 14.666 28.057 2.825 1.00 48.36 ? 650 NAG B C5 1 HETATM 7926 C C6 . NAG J 2 . ? 15.790 29.014 2.440 1.00 50.22 ? 650 NAG B C6 1 HETATM 7927 C C7 . NAG J 2 . ? 10.658 25.082 4.447 1.00 45.48 ? 650 NAG B C7 1 HETATM 7928 C C8 . NAG J 2 . ? 9.583 26.051 4.044 1.00 45.47 ? 650 NAG B C8 1 HETATM 7929 N N2 . NAG J 2 . ? 11.917 25.395 4.109 1.00 45.81 ? 650 NAG B N2 1 HETATM 7930 O O3 . NAG J 2 . ? 12.564 25.436 1.274 1.00 46.69 ? 650 NAG B O3 1 HETATM 7931 O O4 . NAG J 2 . ? 14.729 27.163 0.533 1.00 47.64 ? 650 NAG B O4 1 HETATM 7932 O O5 . NAG J 2 . ? 13.681 28.638 3.673 1.00 47.14 ? 650 NAG B O5 1 HETATM 7933 O O6 . NAG J 2 . ? 15.242 30.228 1.986 1.00 53.09 ? 650 NAG B O6 1 HETATM 7934 O O7 . NAG J 2 . ? 10.360 24.045 5.059 1.00 44.81 ? 650 NAG B O7 1 HETATM 7935 C C1 . NAG K 2 . ? 21.476 -10.859 21.631 1.00 40.68 ? 750 NAG B C1 1 HETATM 7936 C C2 . NAG K 2 . ? 22.899 -10.344 21.820 1.00 41.62 ? 750 NAG B C2 1 HETATM 7937 C C3 . NAG K 2 . ? 23.905 -11.460 21.560 1.00 42.61 ? 750 NAG B C3 1 HETATM 7938 C C4 . NAG K 2 . ? 23.549 -12.736 22.312 1.00 43.42 ? 750 NAG B C4 1 HETATM 7939 C C5 . NAG K 2 . ? 22.081 -13.096 22.080 1.00 43.92 ? 750 NAG B C5 1 HETATM 7940 C C6 . NAG K 2 . ? 21.672 -14.359 22.833 1.00 43.94 ? 750 NAG B C6 1 HETATM 7941 C C7 . NAG K 2 . ? 23.222 -7.981 21.399 1.00 41.91 ? 750 NAG B C7 1 HETATM 7942 C C8 . NAG K 2 . ? 23.484 -6.911 20.383 1.00 41.94 ? 750 NAG B C8 1 HETATM 7943 N N2 . NAG K 2 . ? 23.162 -9.228 20.933 1.00 41.04 ? 750 NAG B N2 1 HETATM 7944 O O3 . NAG K 2 . ? 25.197 -11.033 21.913 1.00 41.35 ? 750 NAG B O3 1 HETATM 7945 O O4 . NAG K 2 . ? 24.385 -13.767 21.835 1.00 45.85 ? 750 NAG B O4 1 HETATM 7946 O O5 . NAG K 2 . ? 21.261 -11.994 22.460 1.00 42.42 ? 750 NAG B O5 1 HETATM 7947 O O6 . NAG K 2 . ? 21.524 -14.047 24.202 1.00 45.79 ? 750 NAG B O6 1 HETATM 7948 O O7 . NAG K 2 . ? 23.059 -7.680 22.585 1.00 42.30 ? 750 NAG B O7 1 HETATM 7949 ZN ZN . ZN L 3 . ? 11.376 8.388 14.038 1.00 30.92 ? 850 ZN B ZN 1 HETATM 7950 C C1 . EDO M 4 . ? 21.956 41.064 22.919 1.00 19.55 ? 950 EDO B C1 1 HETATM 7951 O O1 . EDO M 4 . ? 22.171 40.509 24.182 1.00 21.13 ? 950 EDO B O1 1 HETATM 7952 C C2 . EDO M 4 . ? 23.286 41.288 22.259 1.00 18.23 ? 950 EDO B C2 1 HETATM 7953 O O2 . EDO M 4 . ? 24.149 40.268 22.705 1.00 23.93 ? 950 EDO B O2 1 HETATM 7954 X UNK . UNX N 5 . ? 11.908 9.393 11.140 1.00 29.26 ? 951 UNX B UNK 1 HETATM 7955 O O . HOH O 6 . ? -14.889 -4.049 -14.544 1.00 30.19 ? 509 HOH A O 1 HETATM 7956 O O . HOH O 6 . ? -30.761 -2.137 -17.717 1.00 48.49 ? 510 HOH A O 1 HETATM 7957 O O . HOH O 6 . ? 15.952 12.548 -10.193 1.00 37.11 ? 511 HOH A O 1 HETATM 7958 O O . HOH O 6 . ? -7.685 -8.017 -13.124 1.00 13.14 ? 512 HOH A O 1 HETATM 7959 O O . HOH O 6 . ? 1.346 4.903 -3.019 1.00 10.89 ? 513 HOH A O 1 HETATM 7960 O O . HOH O 6 . ? 1.055 20.747 -39.799 1.00 51.16 ? 514 HOH A O 1 HETATM 7961 O O . HOH O 6 . ? -3.390 -3.832 -16.106 1.00 19.67 ? 515 HOH A O 1 HETATM 7962 O O . HOH O 6 . ? 0.442 -14.937 -15.396 1.00 15.20 ? 516 HOH A O 1 HETATM 7963 O O . HOH O 6 . ? -23.500 -28.904 -22.583 1.00 44.11 ? 517 HOH A O 1 HETATM 7964 O O . HOH O 6 . ? 10.723 -27.351 -10.309 1.00 43.27 ? 518 HOH A O 1 HETATM 7965 O O . HOH O 6 . ? 12.033 -8.757 -3.304 1.00 15.24 ? 519 HOH A O 1 HETATM 7966 O O . HOH O 6 . ? -15.068 16.915 -10.699 1.00 42.64 ? 520 HOH A O 1 HETATM 7967 O O . HOH O 6 . ? 0.971 -11.442 -34.903 1.00 43.28 ? 521 HOH A O 1 HETATM 7968 O O . HOH O 6 . ? -7.226 -32.253 -26.186 1.00 37.87 ? 522 HOH A O 1 HETATM 7969 O O . HOH O 6 . ? 4.118 2.785 -13.926 1.00 13.33 ? 523 HOH A O 1 HETATM 7970 O O . HOH O 6 . ? -10.900 -12.173 -19.219 1.00 17.69 ? 524 HOH A O 1 HETATM 7971 O O . HOH O 6 . ? -4.380 -8.171 -1.943 1.00 19.18 ? 525 HOH A O 1 HETATM 7972 O O . HOH O 6 . ? 0.524 -14.840 -18.094 1.00 16.91 ? 526 HOH A O 1 HETATM 7973 O O . HOH O 6 . ? -18.143 -0.228 -44.847 1.00 45.41 ? 527 HOH A O 1 HETATM 7974 O O . HOH O 6 . ? 0.882 -5.089 -20.788 1.00 19.77 ? 528 HOH A O 1 HETATM 7975 O O . HOH O 6 . ? -17.711 -7.827 -6.908 1.00 17.55 ? 529 HOH A O 1 HETATM 7976 O O . HOH O 6 . ? 21.249 -18.118 -11.266 1.00 36.49 ? 530 HOH A O 1 HETATM 7977 O O . HOH O 6 . ? 1.057 9.215 -9.768 1.00 33.17 ? 531 HOH A O 1 HETATM 7978 O O . HOH O 6 . ? 3.413 -18.018 -24.354 1.00 18.32 ? 532 HOH A O 1 HETATM 7979 O O . HOH O 6 . ? -11.683 2.617 -3.953 1.00 16.55 ? 533 HOH A O 1 HETATM 7980 O O . HOH O 6 . ? -8.675 -2.566 0.024 1.00 21.22 ? 534 HOH A O 1 HETATM 7981 O O . HOH O 6 . ? 3.121 8.308 -5.011 1.00 31.96 ? 535 HOH A O 1 HETATM 7982 O O . HOH O 6 . ? -8.691 -33.840 -20.016 1.00 40.83 ? 536 HOH A O 1 HETATM 7983 O O . HOH O 6 . ? -3.142 -14.262 -17.436 1.00 15.50 ? 537 HOH A O 1 HETATM 7984 O O . HOH O 6 . ? -14.946 -21.127 -2.872 1.00 37.40 ? 538 HOH A O 1 HETATM 7985 O O . HOH O 6 . ? -4.676 8.186 -13.580 1.00 18.50 ? 539 HOH A O 1 HETATM 7986 O O . HOH O 6 . ? -16.592 -4.906 -11.367 1.00 19.49 ? 540 HOH A O 1 HETATM 7987 O O . HOH O 6 . ? 5.813 7.821 -21.314 1.00 21.71 ? 541 HOH A O 1 HETATM 7988 O O . HOH O 6 . ? 10.016 -17.936 -26.995 1.00 23.05 ? 542 HOH A O 1 HETATM 7989 O O . HOH O 6 . ? -18.423 1.031 -16.792 1.00 42.72 ? 543 HOH A O 1 HETATM 7990 O O . HOH O 6 . ? 9.028 -14.486 1.138 1.00 15.76 ? 544 HOH A O 1 HETATM 7991 O O . HOH O 6 . ? -5.273 -5.473 0.502 1.00 16.15 ? 545 HOH A O 1 HETATM 7992 O O . HOH O 6 . ? -9.947 9.235 -5.474 1.00 18.42 ? 546 HOH A O 1 HETATM 7993 O O . HOH O 6 . ? -6.781 -3.736 9.197 1.00 15.80 ? 547 HOH A O 1 HETATM 7994 O O . HOH O 6 . ? 0.490 7.012 -10.173 1.00 19.89 ? 548 HOH A O 1 HETATM 7995 O O . HOH O 6 . ? -10.316 10.283 -22.851 1.00 47.74 ? 549 HOH A O 1 HETATM 7996 O O . HOH O 6 . ? -14.307 -5.031 -9.952 1.00 19.65 ? 551 HOH A O 1 HETATM 7997 O O . HOH O 6 . ? -11.033 -9.987 -29.309 1.00 43.59 ? 552 HOH A O 1 HETATM 7998 O O . HOH O 6 . ? -8.060 -1.220 -11.431 1.00 15.44 ? 553 HOH A O 1 HETATM 7999 O O . HOH O 6 . ? -2.308 6.624 -9.651 1.00 16.80 ? 554 HOH A O 1 HETATM 8000 O O . HOH O 6 . ? 12.167 -4.029 -26.000 1.00 47.43 ? 555 HOH A O 1 HETATM 8001 O O . HOH O 6 . ? -9.356 -30.931 -27.187 1.00 48.84 ? 556 HOH A O 1 HETATM 8002 O O . HOH O 6 . ? -12.585 13.706 -25.290 1.00 43.79 ? 557 HOH A O 1 HETATM 8003 O O . HOH O 6 . ? -17.009 -21.170 -10.923 1.00 24.44 ? 558 HOH A O 1 HETATM 8004 O O . HOH O 6 . ? -22.730 2.215 -10.663 1.00 61.46 ? 559 HOH A O 1 HETATM 8005 O O . HOH O 6 . ? -14.224 7.288 -43.556 1.00 25.21 ? 560 HOH A O 1 HETATM 8006 O O . HOH O 6 . ? 8.388 -11.699 -4.656 1.00 24.68 ? 561 HOH A O 1 HETATM 8007 O O . HOH O 6 . ? -14.201 0.419 -7.414 1.00 22.26 ? 562 HOH A O 1 HETATM 8008 O O . HOH O 6 . ? -4.943 -6.910 -7.245 1.00 16.95 ? 563 HOH A O 1 HETATM 8009 O O . HOH O 6 . ? -7.416 8.219 -5.563 1.00 42.55 ? 564 HOH A O 1 HETATM 8010 O O . HOH O 6 . ? -5.430 -6.251 -9.984 1.00 16.74 ? 565 HOH A O 1 HETATM 8011 O O . HOH O 6 . ? -8.224 1.700 -44.214 1.00 48.30 ? 566 HOH A O 1 HETATM 8012 O O . HOH O 6 . ? -15.190 -23.604 -2.289 1.00 48.50 ? 567 HOH A O 1 HETATM 8013 O O . HOH O 6 . ? 7.058 -20.979 -2.829 1.00 44.80 ? 568 HOH A O 1 HETATM 8014 O O . HOH O 6 . ? -23.839 -7.700 -21.678 1.00 22.94 ? 569 HOH A O 1 HETATM 8015 O O . HOH O 6 . ? -19.696 -5.962 -26.719 1.00 26.95 ? 570 HOH A O 1 HETATM 8016 O O . HOH O 6 . ? -30.897 -11.495 -27.800 1.00 41.59 ? 571 HOH A O 1 HETATM 8017 O O . HOH O 6 . ? -20.344 -21.125 -9.676 1.00 37.89 ? 572 HOH A O 1 HETATM 8018 O O . HOH O 6 . ? -14.366 -21.240 -5.362 1.00 43.08 ? 573 HOH A O 1 HETATM 8019 O O . HOH O 6 . ? -9.279 -1.400 -28.231 1.00 25.22 ? 574 HOH A O 1 HETATM 8020 O O . HOH O 6 . ? 5.083 -15.406 -31.033 1.00 27.76 ? 575 HOH A O 1 HETATM 8021 O O . HOH O 6 . ? -16.518 -6.810 -20.250 1.00 21.00 ? 576 HOH A O 1 HETATM 8022 O O . HOH O 6 . ? -19.806 5.031 -31.073 1.00 25.94 ? 577 HOH A O 1 HETATM 8023 O O . HOH O 6 . ? -18.191 4.712 -37.982 1.00 47.98 ? 578 HOH A O 1 HETATM 8024 O O . HOH O 6 . ? 5.643 6.270 -2.612 1.00 20.88 ? 579 HOH A O 1 HETATM 8025 O O . HOH O 6 . ? -7.490 -7.314 -38.614 1.00 23.96 ? 580 HOH A O 1 HETATM 8026 O O . HOH O 6 . ? -28.737 4.877 -42.883 1.00 47.54 ? 581 HOH A O 1 HETATM 8027 O O . HOH O 6 . ? -15.328 -22.733 -17.352 1.00 26.00 ? 582 HOH A O 1 HETATM 8028 O O . HOH O 6 . ? -30.372 -0.922 -10.602 1.00 52.33 ? 583 HOH A O 1 HETATM 8029 O O . HOH O 6 . ? -21.337 -9.096 -1.619 1.00 20.91 ? 584 HOH A O 1 HETATM 8030 O O . HOH O 6 . ? -16.458 8.313 -44.227 1.00 25.76 ? 585 HOH A O 1 HETATM 8031 O O . HOH O 6 . ? -21.350 14.533 -44.960 1.00 44.48 ? 586 HOH A O 1 HETATM 8032 O O . HOH O 6 . ? 11.231 6.312 -6.877 1.00 31.33 ? 587 HOH A O 1 HETATM 8033 O O . HOH O 6 . ? 10.960 7.144 -4.384 1.00 24.92 ? 588 HOH A O 1 HETATM 8034 O O . HOH O 6 . ? 15.506 -14.103 1.135 1.00 21.32 ? 589 HOH A O 1 HETATM 8035 O O . HOH O 6 . ? 14.645 -20.152 -4.748 1.00 38.30 ? 590 HOH A O 1 HETATM 8036 O O . HOH O 6 . ? -11.846 25.038 -42.272 1.00 50.85 ? 591 HOH A O 1 HETATM 8037 O O . HOH O 6 . ? 25.161 -18.968 8.905 1.00 45.23 ? 592 HOH A O 1 HETATM 8038 O O . HOH O 6 . ? 16.327 -13.640 -5.934 1.00 25.47 ? 593 HOH A O 1 HETATM 8039 O O . HOH O 6 . ? -29.420 -9.962 -1.293 1.00 55.14 ? 594 HOH A O 1 HETATM 8040 O O . HOH O 6 . ? -30.360 -22.913 -20.951 1.00 39.14 ? 595 HOH A O 1 HETATM 8041 O O . HOH O 6 . ? 4.835 -20.563 -0.936 1.00 41.51 ? 596 HOH A O 1 HETATM 8042 O O . HOH O 6 . ? 2.537 11.652 -13.759 1.00 19.96 ? 597 HOH A O 1 HETATM 8043 O O . HOH O 6 . ? 6.359 -24.292 -29.393 1.00 25.06 ? 598 HOH A O 1 HETATM 8044 O O . HOH O 6 . ? 3.907 -5.673 -24.696 1.00 25.83 ? 599 HOH A O 1 HETATM 8045 O O . HOH O 6 . ? 12.117 5.477 -2.752 1.00 29.41 ? 600 HOH A O 1 HETATM 8046 O O . HOH O 6 . ? -16.036 12.101 -26.455 1.00 48.49 ? 601 HOH A O 1 HETATM 8047 O O . HOH O 6 . ? 24.126 -20.283 6.110 1.00 47.21 ? 602 HOH A O 1 HETATM 8048 O O . HOH O 6 . ? -4.005 2.249 -27.378 1.00 21.66 ? 603 HOH A O 1 HETATM 8049 O O . HOH O 6 . ? 3.774 -0.871 1.017 1.00 24.55 ? 604 HOH A O 1 HETATM 8050 O O . HOH O 6 . ? 15.001 -17.825 -5.814 1.00 25.54 ? 605 HOH A O 1 HETATM 8051 O O . HOH O 6 . ? -18.586 -23.606 -10.425 1.00 42.04 ? 606 HOH A O 1 HETATM 8052 O O . HOH O 6 . ? -24.173 14.860 -43.363 1.00 48.89 ? 607 HOH A O 1 HETATM 8053 O O . HOH O 6 . ? 19.417 -19.208 -8.799 1.00 41.91 ? 608 HOH A O 1 HETATM 8054 O O . HOH O 6 . ? -30.833 6.319 -42.566 1.00 51.63 ? 610 HOH A O 1 HETATM 8055 O O . HOH O 6 . ? -27.905 -15.974 -34.295 1.00 42.96 ? 611 HOH A O 1 HETATM 8056 O O . HOH O 6 . ? -18.270 -9.133 -10.254 1.00 20.58 ? 612 HOH A O 1 HETATM 8057 O O . HOH O 6 . ? -2.310 -2.824 -19.140 1.00 23.89 ? 613 HOH A O 1 HETATM 8058 O O . HOH O 6 . ? 24.314 -5.744 -11.589 1.00 26.25 ? 614 HOH A O 1 HETATM 8059 O O . HOH O 6 . ? -24.081 -9.729 -31.952 1.00 29.01 ? 615 HOH A O 1 HETATM 8060 O O . HOH O 6 . ? -30.930 -6.716 -4.314 1.00 43.52 ? 616 HOH A O 1 HETATM 8061 O O . HOH O 6 . ? -15.240 -2.174 -43.544 1.00 27.51 ? 617 HOH A O 1 HETATM 8062 O O . HOH O 6 . ? -1.694 1.038 -26.500 1.00 27.26 ? 618 HOH A O 1 HETATM 8063 O O . HOH O 6 . ? 18.063 -0.306 -20.362 1.00 54.86 ? 619 HOH A O 1 HETATM 8064 O O . HOH O 6 . ? -16.993 -26.371 -17.753 1.00 51.97 ? 620 HOH A O 1 HETATM 8065 O O . HOH O 6 . ? 16.507 -14.750 -2.724 1.00 34.20 ? 621 HOH A O 1 HETATM 8066 O O . HOH O 6 . ? -13.889 -10.188 1.486 1.00 20.58 ? 622 HOH A O 1 HETATM 8067 O O . HOH O 6 . ? -20.840 -8.610 -29.519 1.00 24.54 ? 623 HOH A O 1 HETATM 8068 O O . HOH O 6 . ? -19.190 -13.184 -38.572 1.00 32.55 ? 624 HOH A O 1 HETATM 8069 O O . HOH O 6 . ? 5.008 -20.721 -5.456 1.00 36.92 ? 625 HOH A O 1 HETATM 8070 O O . HOH O 6 . ? 7.602 -22.453 -5.456 1.00 31.92 ? 626 HOH A O 1 HETATM 8071 O O . HOH O 6 . ? -20.190 -3.554 -4.623 1.00 21.08 ? 627 HOH A O 1 HETATM 8072 O O . HOH O 6 . ? 0.379 -12.457 -37.184 1.00 43.23 ? 628 HOH A O 1 HETATM 8073 O O . HOH O 6 . ? -16.724 5.937 -5.842 1.00 21.90 ? 629 HOH A O 1 HETATM 8074 O O . HOH O 6 . ? -21.876 5.014 -29.201 1.00 28.08 ? 630 HOH A O 1 HETATM 8075 O O . HOH O 6 . ? -21.531 12.844 -48.799 1.00 39.06 ? 631 HOH A O 1 HETATM 8076 O O . HOH O 6 . ? 12.315 -9.855 -0.618 1.00 23.28 ? 632 HOH A O 1 HETATM 8077 O O . HOH O 6 . ? -21.336 2.230 -0.616 1.00 39.54 ? 633 HOH A O 1 HETATM 8078 O O . HOH O 6 . ? -10.512 -20.750 -29.844 1.00 32.72 ? 634 HOH A O 1 HETATM 8079 O O . HOH O 6 . ? 16.380 5.080 -13.419 1.00 26.97 ? 635 HOH A O 1 HETATM 8080 O O . HOH O 6 . ? 12.887 -17.005 -4.357 1.00 29.09 ? 636 HOH A O 1 HETATM 8081 O O . HOH O 6 . ? -4.686 10.420 -11.707 1.00 22.65 ? 637 HOH A O 1 HETATM 8082 O O . HOH O 6 . ? 17.155 -24.707 -21.323 1.00 43.91 ? 638 HOH A O 1 HETATM 8083 O O . HOH O 6 . ? -7.486 20.074 -37.601 1.00 52.87 ? 639 HOH A O 1 HETATM 8084 O O . HOH O 6 . ? -19.609 1.428 -13.983 1.00 27.81 ? 640 HOH A O 1 HETATM 8085 O O . HOH O 6 . ? 16.990 2.492 -13.690 1.00 20.90 ? 641 HOH A O 1 HETATM 8086 O O . HOH O 6 . ? 19.443 -17.418 -6.955 1.00 43.92 ? 642 HOH A O 1 HETATM 8087 O O . HOH O 6 . ? -24.562 16.467 -45.436 1.00 48.21 ? 643 HOH A O 1 HETATM 8088 O O . HOH O 6 . ? 17.483 -23.487 -23.453 1.00 43.68 ? 644 HOH A O 1 HETATM 8089 O O . HOH O 6 . ? -14.381 -23.146 -14.607 1.00 39.86 ? 645 HOH A O 1 HETATM 8090 O O . HOH O 6 . ? -24.960 -4.315 1.865 1.00 52.31 ? 646 HOH A O 1 HETATM 8091 O O . HOH O 6 . ? -35.810 -11.873 -14.402 1.00 34.24 ? 647 HOH A O 1 HETATM 8092 O O . HOH O 6 . ? -3.563 -11.528 5.163 1.00 46.51 ? 648 HOH A O 1 HETATM 8093 O O . HOH O 6 . ? 20.207 -17.747 3.749 1.00 30.42 ? 649 HOH A O 1 HETATM 8094 O O . HOH O 6 . ? 2.210 -20.298 -34.774 1.00 28.12 ? 651 HOH A O 1 HETATM 8095 O O . HOH O 6 . ? 7.765 -2.328 -2.450 1.00 39.48 ? 652 HOH A O 1 HETATM 8096 O O . HOH O 6 . ? 18.688 2.242 -15.769 1.00 45.57 ? 653 HOH A O 1 HETATM 8097 O O . HOH O 6 . ? 22.524 -13.942 6.447 1.00 36.63 ? 654 HOH A O 1 HETATM 8098 O O . HOH O 6 . ? -17.483 -21.733 -0.905 1.00 49.63 ? 655 HOH A O 1 HETATM 8099 O O . HOH O 6 . ? 16.550 0.938 -17.777 1.00 43.93 ? 656 HOH A O 1 HETATM 8100 O O . HOH O 6 . ? 11.197 -17.099 -6.682 1.00 30.63 ? 657 HOH A O 1 HETATM 8101 O O . HOH O 6 . ? -31.140 -20.757 -20.085 1.00 34.13 ? 658 HOH A O 1 HETATM 8102 O O . HOH O 6 . ? 4.335 10.142 -12.318 1.00 27.44 ? 659 HOH A O 1 HETATM 8103 O O . HOH O 6 . ? 17.577 -19.764 -28.890 1.00 46.21 ? 660 HOH A O 1 HETATM 8104 O O . HOH O 6 . ? 2.238 -6.801 -29.273 1.00 31.49 ? 661 HOH A O 1 HETATM 8105 O O . HOH O 6 . ? -24.302 -3.389 -1.569 1.00 52.83 ? 662 HOH A O 1 HETATM 8106 O O . HOH O 6 . ? -14.062 -1.022 -10.056 1.00 35.56 ? 663 HOH A O 1 HETATM 8107 O O . HOH O 6 . ? -12.452 7.267 -46.157 1.00 52.20 ? 664 HOH A O 1 HETATM 8108 O O . HOH O 6 . ? -23.934 -5.917 -0.053 1.00 25.53 ? 665 HOH A O 1 HETATM 8109 O O . HOH O 6 . ? -28.808 -18.458 -24.703 1.00 44.54 ? 666 HOH A O 1 HETATM 8110 O O . HOH O 6 . ? 0.108 6.077 -25.540 1.00 45.08 ? 667 HOH A O 1 HETATM 8111 O O . HOH O 6 . ? 5.829 -21.915 2.635 1.00 47.49 ? 668 HOH A O 1 HETATM 8112 O O . HOH O 6 . ? -23.361 -21.683 -10.543 1.00 27.00 ? 669 HOH A O 1 HETATM 8113 O O . HOH O 6 . ? -32.466 -20.871 -17.988 1.00 44.14 ? 670 HOH A O 1 HETATM 8114 O O . HOH O 6 . ? -18.458 -8.807 -27.493 1.00 25.51 ? 671 HOH A O 1 HETATM 8115 O O . HOH O 6 . ? -1.853 17.126 -42.488 1.00 65.45 ? 672 HOH A O 1 HETATM 8116 O O . HOH O 6 . ? -23.400 4.688 -32.983 1.00 34.87 ? 673 HOH A O 1 HETATM 8117 O O . HOH O 6 . ? -1.366 -16.074 1.042 1.00 29.63 ? 674 HOH A O 1 HETATM 8118 O O . HOH O 6 . ? 12.666 -25.296 -27.629 1.00 37.74 ? 675 HOH A O 1 HETATM 8119 O O . HOH O 6 . ? 1.035 -18.896 -7.350 1.00 32.41 ? 676 HOH A O 1 HETATM 8120 O O . HOH O 6 . ? 3.112 -3.338 -0.936 1.00 34.63 ? 677 HOH A O 1 HETATM 8121 O O . HOH O 6 . ? -30.869 -10.812 -4.896 1.00 32.31 ? 678 HOH A O 1 HETATM 8122 O O . HOH O 6 . ? 7.667 -11.314 -28.144 1.00 27.44 ? 679 HOH A O 1 HETATM 8123 O O . HOH O 6 . ? -0.925 -6.364 1.516 1.00 27.97 ? 680 HOH A O 1 HETATM 8124 O O . HOH O 6 . ? -10.258 -23.170 -29.051 1.00 47.07 ? 681 HOH A O 1 HETATM 8125 O O . HOH O 6 . ? -21.814 -7.817 2.958 1.00 34.57 ? 682 HOH A O 1 HETATM 8126 O O . HOH O 6 . ? -11.103 12.285 -23.537 1.00 49.32 ? 683 HOH A O 1 HETATM 8127 O O . HOH O 6 . ? 14.697 2.896 -18.764 1.00 43.26 ? 684 HOH A O 1 HETATM 8128 O O . HOH O 6 . ? -1.989 6.706 -27.027 1.00 50.33 ? 685 HOH A O 1 HETATM 8129 O O . HOH O 6 . ? -25.500 -9.294 -29.180 1.00 27.56 ? 686 HOH A O 1 HETATM 8130 O O . HOH O 6 . ? 18.704 -17.472 1.161 1.00 33.54 ? 687 HOH A O 1 HETATM 8131 O O . HOH O 6 . ? -9.789 -6.147 7.399 1.00 21.02 ? 688 HOH A O 1 HETATM 8132 O O . HOH O 6 . ? 3.006 12.257 -22.636 1.00 44.38 ? 689 HOH A O 1 HETATM 8133 O O . HOH O 6 . ? 24.686 -22.050 -15.206 1.00 43.90 ? 690 HOH A O 1 HETATM 8134 O O . HOH O 6 . ? 13.411 -27.555 -26.864 1.00 49.86 ? 691 HOH A O 1 HETATM 8135 O O . HOH O 6 . ? -23.251 -4.612 -43.620 1.00 44.22 ? 692 HOH A O 1 HETATM 8136 O O . HOH O 6 . ? -11.480 -26.219 -23.557 1.00 34.82 ? 693 HOH A O 1 HETATM 8137 O O . HOH O 6 . ? 11.887 -8.055 -27.652 1.00 51.81 ? 694 HOH A O 1 HETATM 8138 O O . HOH O 6 . ? -28.931 -7.744 -43.081 1.00 29.33 ? 695 HOH A O 1 HETATM 8139 O O . HOH O 6 . ? 17.643 -15.436 -7.970 1.00 34.60 ? 696 HOH A O 1 HETATM 8140 O O . HOH O 6 . ? 16.940 -24.516 -8.779 1.00 35.33 ? 697 HOH A O 1 HETATM 8141 O O . HOH O 6 . ? -22.552 -26.713 -21.447 1.00 43.61 ? 698 HOH A O 1 HETATM 8142 O O . HOH O 6 . ? 1.812 -12.354 4.855 1.00 46.23 ? 699 HOH A O 1 HETATM 8143 O O . HOH O 6 . ? -21.500 -6.881 0.160 1.00 22.10 ? 700 HOH A O 1 HETATM 8144 O O . HOH O 6 . ? -16.874 7.133 -46.811 1.00 36.19 ? 701 HOH A O 1 HETATM 8145 O O . HOH O 6 . ? -31.495 -2.300 -15.164 1.00 30.82 ? 702 HOH A O 1 HETATM 8146 O O . HOH O 6 . ? -4.808 -6.629 -38.399 1.00 35.62 ? 703 HOH A O 1 HETATM 8147 O O . HOH O 6 . ? -10.830 2.765 -9.193 1.00 24.15 ? 704 HOH A O 1 HETATM 8148 O O . HOH O 6 . ? -27.626 0.561 -16.050 1.00 40.44 ? 705 HOH A O 1 HETATM 8149 O O . HOH O 6 . ? -3.248 4.210 -28.719 1.00 35.50 ? 706 HOH A O 1 HETATM 8150 O O . HOH O 6 . ? -12.727 1.488 4.642 1.00 28.39 ? 707 HOH A O 1 HETATM 8151 O O . HOH O 6 . ? -25.006 15.294 -47.914 1.00 53.56 ? 708 HOH A O 1 HETATM 8152 O O . HOH O 6 . ? -32.220 -14.770 -20.961 1.00 32.39 ? 709 HOH A O 1 HETATM 8153 O O . HOH O 6 . ? 22.084 3.082 -5.953 1.00 32.58 ? 710 HOH A O 1 HETATM 8154 O O . HOH O 6 . ? 23.323 0.583 -11.770 1.00 27.18 ? 711 HOH A O 1 HETATM 8155 O O . HOH O 6 . ? -21.565 -2.556 -2.393 1.00 32.75 ? 712 HOH A O 1 HETATM 8156 O O . HOH O 6 . ? -1.642 15.505 -22.695 1.00 34.47 ? 713 HOH A O 1 HETATM 8157 O O . HOH O 6 . ? -13.059 -20.501 -39.361 1.00 37.82 ? 714 HOH A O 1 HETATM 8158 O O . HOH O 6 . ? -22.593 16.224 -34.593 1.00 31.02 ? 715 HOH A O 1 HETATM 8159 O O . HOH O 6 . ? -3.521 -1.813 -33.423 1.00 36.15 ? 716 HOH A O 1 HETATM 8160 O O . HOH O 6 . ? -18.343 -4.269 -25.335 1.00 28.40 ? 717 HOH A O 1 HETATM 8161 O O . HOH O 6 . ? -15.616 -3.973 -22.338 1.00 47.18 ? 718 HOH A O 1 HETATM 8162 O O . HOH O 6 . ? 23.037 -11.965 -25.573 1.00 44.61 ? 719 HOH A O 1 HETATM 8163 O O . HOH O 6 . ? -30.408 -9.043 -19.715 1.00 40.15 ? 720 HOH A O 1 HETATM 8164 O O . HOH O 6 . ? 14.416 -23.978 -5.336 1.00 36.95 ? 721 HOH A O 1 HETATM 8165 O O . HOH O 6 . ? -14.309 9.492 -25.527 1.00 30.59 ? 722 HOH A O 1 HETATM 8166 O O . HOH O 6 . ? -25.716 -20.632 -9.249 1.00 33.57 ? 723 HOH A O 1 HETATM 8167 O O . HOH O 6 . ? -3.035 -2.342 -26.837 1.00 26.62 ? 724 HOH A O 1 HETATM 8168 O O . HOH O 6 . ? -10.933 19.734 -49.365 1.00 47.84 ? 725 HOH A O 1 HETATM 8169 O O . HOH O 6 . ? 10.072 -12.586 -0.619 1.00 39.33 ? 726 HOH A O 1 HETATM 8170 O O . HOH O 6 . ? 7.822 -21.287 -32.163 1.00 48.56 ? 727 HOH A O 1 HETATM 8171 O O . HOH O 6 . ? -9.417 -22.721 -13.805 1.00 31.13 ? 728 HOH A O 1 HETATM 8172 O O . HOH O 6 . ? -11.675 9.678 -44.367 1.00 46.41 ? 729 HOH A O 1 HETATM 8173 O O . HOH O 6 . ? -15.728 15.161 -8.988 1.00 31.02 ? 730 HOH A O 1 HETATM 8174 O O . HOH O 6 . ? 2.127 -14.206 6.591 1.00 48.65 ? 731 HOH A O 1 HETATM 8175 O O . HOH O 6 . ? -28.269 -15.167 -28.578 1.00 31.18 ? 732 HOH A O 1 HETATM 8176 O O . HOH O 6 . ? 11.502 -15.752 -27.233 1.00 29.29 ? 733 HOH A O 1 HETATM 8177 O O . HOH O 6 . ? -21.140 -5.285 7.881 1.00 44.72 ? 734 HOH A O 1 HETATM 8178 O O . HOH O 6 . ? -7.178 11.340 -23.393 1.00 31.59 ? 735 HOH A O 1 HETATM 8179 O O . HOH O 6 . ? -16.924 12.513 -49.334 1.00 55.18 ? 736 HOH A O 1 HETATM 8180 O O . HOH O 6 . ? 16.931 5.365 -2.802 1.00 32.71 ? 737 HOH A O 1 HETATM 8181 O O . HOH O 6 . ? -6.161 -25.329 -11.754 1.00 46.93 ? 738 HOH A O 1 HETATM 8182 O O . HOH O 6 . ? 18.145 -15.058 0.021 1.00 40.31 ? 739 HOH A O 1 HETATM 8183 O O . HOH O 6 . ? -27.961 -12.905 -35.291 1.00 36.84 ? 740 HOH A O 1 HETATM 8184 O O . HOH O 6 . ? -27.914 13.306 -39.371 1.00 40.49 ? 741 HOH A O 1 HETATM 8185 O O . HOH O 6 . ? -3.028 -5.115 -26.984 1.00 28.61 ? 742 HOH A O 1 HETATM 8186 O O . HOH O 6 . ? -20.991 -3.879 -45.027 1.00 36.26 ? 743 HOH A O 1 HETATM 8187 O O . HOH O 6 . ? -8.285 -23.701 -9.177 1.00 30.88 ? 744 HOH A O 1 HETATM 8188 O O . HOH O 6 . ? 7.858 9.550 -25.063 1.00 48.80 ? 745 HOH A O 1 HETATM 8189 O O . HOH O 6 . ? 9.320 -26.781 -12.634 1.00 55.28 ? 746 HOH A O 1 HETATM 8190 O O . HOH O 6 . ? 23.250 -16.689 -10.453 1.00 51.58 ? 747 HOH A O 1 HETATM 8191 O O . HOH O 6 . ? 5.247 7.644 -6.218 1.00 38.37 ? 748 HOH A O 1 HETATM 8192 O O . HOH O 6 . ? -14.744 -14.985 -39.996 1.00 47.75 ? 749 HOH A O 1 HETATM 8193 O O . HOH O 6 . ? -1.824 -0.151 -34.256 1.00 36.88 ? 751 HOH A O 1 HETATM 8194 O O . HOH O 6 . ? 6.359 -0.106 -0.314 1.00 28.33 ? 752 HOH A O 1 HETATM 8195 O O . HOH O 6 . ? 2.838 14.311 -14.520 1.00 31.85 ? 753 HOH A O 1 HETATM 8196 O O . HOH O 6 . ? 4.797 -17.024 -36.460 1.00 46.95 ? 754 HOH A O 1 HETATM 8197 O O . HOH O 6 . ? -13.904 -23.453 -20.858 1.00 55.05 ? 755 HOH A O 1 HETATM 8198 O O . HOH O 6 . ? -17.842 7.741 -12.217 1.00 35.56 ? 756 HOH A O 1 HETATM 8199 O O . HOH O 6 . ? -24.442 -28.663 -24.824 1.00 42.29 ? 757 HOH A O 1 HETATM 8200 O O . HOH O 6 . ? -3.274 6.456 -4.447 1.00 27.87 ? 758 HOH A O 1 HETATM 8201 O O . HOH O 6 . ? -14.765 5.071 -4.009 1.00 47.14 ? 759 HOH A O 1 HETATM 8202 O O . HOH O 6 . ? 2.308 14.696 -16.843 1.00 44.14 ? 760 HOH A O 1 HETATM 8203 O O . HOH O 6 . ? -14.794 -10.225 4.329 1.00 39.36 ? 761 HOH A O 1 HETATM 8204 O O . HOH O 6 . ? -4.078 -9.685 6.762 1.00 30.87 ? 762 HOH A O 1 HETATM 8205 O O . HOH O 6 . ? 8.422 -13.885 -6.239 1.00 29.92 ? 763 HOH A O 1 HETATM 8206 O O . HOH O 6 . ? -18.744 5.338 -11.769 1.00 32.28 ? 764 HOH A O 1 HETATM 8207 O O . HOH O 6 . ? 28.087 -13.719 -16.157 1.00 53.36 ? 765 HOH A O 1 HETATM 8208 O O . HOH O 6 . ? -24.124 -2.136 -30.416 1.00 51.02 ? 766 HOH A O 1 HETATM 8209 O O . HOH O 6 . ? -11.569 -23.951 -14.723 1.00 35.91 ? 767 HOH A O 1 HETATM 8210 O O . HOH O 6 . ? -17.030 -14.852 -38.694 1.00 35.83 ? 768 HOH A O 1 HETATM 8211 O O . HOH O 6 . ? -2.366 2.125 -36.881 1.00 49.66 ? 769 HOH A O 1 HETATM 8212 O O . HOH O 6 . ? -18.579 -25.066 -28.660 1.00 35.67 ? 770 HOH A O 1 HETATM 8213 O O . HOH O 6 . ? -24.783 13.365 -23.986 1.00 52.58 ? 771 HOH A O 1 HETATM 8214 O O . HOH O 6 . ? 4.071 -22.216 -35.297 1.00 43.39 ? 772 HOH A O 1 HETATM 8215 O O . HOH O 6 . ? -10.444 -32.105 -17.814 1.00 38.38 ? 773 HOH A O 1 HETATM 8216 O O . HOH O 6 . ? -21.154 0.265 -11.407 1.00 30.79 ? 774 HOH A O 1 HETATM 8217 O O . HOH O 6 . ? 19.982 -18.492 -28.857 1.00 46.99 ? 775 HOH A O 1 HETATM 8218 O O . HOH O 6 . ? 14.002 -14.944 -27.616 1.00 34.55 ? 776 HOH A O 1 HETATM 8219 O O . HOH O 6 . ? 2.156 7.169 -22.294 1.00 34.00 ? 777 HOH A O 1 HETATM 8220 O O . HOH O 6 . ? -23.298 -23.491 -17.211 1.00 43.34 ? 778 HOH A O 1 HETATM 8221 O O . HOH O 6 . ? 24.070 -15.127 8.390 1.00 29.82 ? 779 HOH A O 1 HETATM 8222 O O . HOH O 6 . ? 20.256 -1.868 -18.109 1.00 59.98 ? 780 HOH A O 1 HETATM 8223 O O . HOH O 6 . ? -12.332 -5.619 7.799 1.00 23.66 ? 781 HOH A O 1 HETATM 8224 O O . HOH O 6 . ? 11.415 -25.248 -12.954 1.00 32.59 ? 782 HOH A O 1 HETATM 8225 O O . HOH O 6 . ? -21.555 -13.878 -40.385 1.00 47.68 ? 783 HOH A O 1 HETATM 8226 O O . HOH O 6 . ? -20.663 -23.845 -8.723 1.00 51.08 ? 784 HOH A O 1 HETATM 8227 O O . HOH O 6 . ? 5.048 -4.061 -26.622 1.00 45.23 ? 785 HOH A O 1 HETATM 8228 O O . HOH O 6 . ? -16.629 -8.875 -43.914 1.00 41.54 ? 786 HOH A O 1 HETATM 8229 O O . HOH O 6 . ? 22.965 -26.156 -19.805 1.00 63.61 ? 787 HOH A O 1 HETATM 8230 O O . HOH O 6 . ? -12.867 3.054 -7.484 1.00 28.55 ? 788 HOH A O 1 HETATM 8231 O O . HOH O 6 . ? -25.760 1.281 -40.044 1.00 35.69 ? 789 HOH A O 1 HETATM 8232 O O . HOH O 6 . ? -17.431 12.683 -12.624 1.00 51.26 ? 790 HOH A O 1 HETATM 8233 O O . HOH O 6 . ? -11.734 15.635 -6.618 1.00 43.02 ? 791 HOH A O 1 HETATM 8234 O O . HOH O 6 . ? -3.549 7.010 -7.293 1.00 35.27 ? 792 HOH A O 1 HETATM 8235 O O . HOH O 6 . ? -36.241 -8.017 -22.115 1.00 39.37 ? 793 HOH A O 1 HETATM 8236 O O . HOH O 6 . ? 11.334 10.978 -9.292 1.00 45.58 ? 794 HOH A O 1 HETATM 8237 O O . HOH O 6 . ? -5.362 11.484 -44.058 1.00 46.89 ? 795 HOH A O 1 HETATM 8238 O O . HOH O 6 . ? 17.635 -6.726 -23.025 1.00 32.79 ? 796 HOH A O 1 HETATM 8239 O O . HOH O 6 . ? -31.937 -17.226 -22.490 1.00 55.22 ? 797 HOH A O 1 HETATM 8240 O O . HOH O 6 . ? -34.524 -15.787 -19.843 1.00 37.83 ? 798 HOH A O 1 HETATM 8241 O O . HOH O 6 . ? -25.927 -5.546 -21.951 1.00 35.69 ? 799 HOH A O 1 HETATM 8242 O O . HOH O 6 . ? 3.455 7.800 -8.513 1.00 46.99 ? 800 HOH A O 1 HETATM 8243 O O . HOH O 6 . ? -19.715 -2.749 6.631 1.00 37.48 ? 801 HOH A O 1 HETATM 8244 O O . HOH O 6 . ? -26.003 -24.109 -18.831 1.00 34.97 ? 802 HOH A O 1 HETATM 8245 O O . HOH O 6 . ? -14.676 -8.567 -41.653 1.00 46.55 ? 803 HOH A O 1 HETATM 8246 O O . HOH O 6 . ? 0.922 4.980 -21.366 1.00 44.15 ? 804 HOH A O 1 HETATM 8247 O O . HOH O 6 . ? -36.300 -9.048 -24.202 1.00 39.49 ? 805 HOH A O 1 HETATM 8248 O O . HOH O 6 . ? -33.810 -20.543 -15.196 1.00 35.37 ? 806 HOH A O 1 HETATM 8249 O O . HOH O 6 . ? 21.597 -10.578 3.306 1.00 37.01 ? 807 HOH A O 1 HETATM 8250 O O . HOH O 6 . ? -15.690 -2.847 -17.247 1.00 37.34 ? 808 HOH A O 1 HETATM 8251 O O . HOH O 6 . ? 9.781 -18.662 -29.737 1.00 35.00 ? 809 HOH A O 1 HETATM 8252 O O . HOH O 6 . ? -28.324 -25.216 -18.741 1.00 37.37 ? 810 HOH A O 1 HETATM 8253 O O . HOH O 6 . ? -20.105 -25.247 -11.598 1.00 46.79 ? 811 HOH A O 1 HETATM 8254 O O . HOH O 6 . ? -26.806 1.909 -43.256 1.00 37.74 ? 812 HOH A O 1 HETATM 8255 O O . HOH O 6 . ? -2.854 9.300 -36.731 1.00 45.78 ? 813 HOH A O 1 HETATM 8256 O O . HOH O 6 . ? 22.268 -15.618 3.947 1.00 36.68 ? 814 HOH A O 1 HETATM 8257 O O . HOH O 6 . ? -14.517 4.670 -6.343 1.00 40.37 ? 815 HOH A O 1 HETATM 8258 O O . HOH O 6 . ? -17.547 13.342 -10.210 1.00 45.33 ? 816 HOH A O 1 HETATM 8259 O O . HOH O 6 . ? -8.266 -9.019 -40.470 1.00 41.37 ? 817 HOH A O 1 HETATM 8260 O O . HOH O 6 . ? -23.783 -14.966 -0.528 1.00 46.47 ? 818 HOH A O 1 HETATM 8261 O O . HOH O 6 . ? 20.906 -28.747 -16.129 1.00 44.93 ? 819 HOH A O 1 HETATM 8262 O O . HOH O 6 . ? 12.309 -20.070 11.823 1.00 49.23 ? 820 HOH A O 1 HETATM 8263 O O . HOH O 6 . ? -37.226 -9.783 -17.682 1.00 40.15 ? 821 HOH A O 1 HETATM 8264 O O . HOH O 6 . ? -21.026 -7.744 -43.047 1.00 33.31 ? 822 HOH A O 1 HETATM 8265 O O . HOH O 6 . ? -22.436 -17.221 -38.026 1.00 47.18 ? 823 HOH A O 1 HETATM 8266 O O . HOH O 6 . ? -3.223 14.802 -30.165 1.00 63.69 ? 824 HOH A O 1 HETATM 8267 O O . HOH O 6 . ? -12.809 13.726 -22.237 1.00 51.17 ? 825 HOH A O 1 HETATM 8268 O O . HOH O 6 . ? -15.261 -25.014 -18.401 1.00 50.44 ? 826 HOH A O 1 HETATM 8269 O O . HOH O 6 . ? 2.576 0.089 -26.522 1.00 49.56 ? 827 HOH A O 1 HETATM 8270 O O . HOH O 6 . ? -19.766 -22.517 -1.527 1.00 48.50 ? 828 HOH A O 1 HETATM 8271 O O . HOH O 6 . ? 13.989 -12.098 2.119 1.00 33.50 ? 829 HOH A O 1 HETATM 8272 O O . HOH O 6 . ? -30.684 -5.386 -32.061 1.00 68.53 ? 830 HOH A O 1 HETATM 8273 O O . HOH O 6 . ? -8.772 -0.471 -44.886 1.00 54.63 ? 831 HOH A O 1 HETATM 8274 O O . HOH O 6 . ? 24.928 -10.077 -10.255 1.00 50.21 ? 832 HOH A O 1 HETATM 8275 O O . HOH O 6 . ? -26.237 16.298 -22.143 1.00 67.52 ? 833 HOH A O 1 HETATM 8276 O O . HOH O 6 . ? 19.219 -24.917 -9.826 1.00 39.82 ? 834 HOH A O 1 HETATM 8277 O O . HOH O 6 . ? 8.709 -23.291 -30.303 1.00 50.57 ? 835 HOH A O 1 HETATM 8278 O O . HOH O 6 . ? -10.504 -22.481 -26.718 1.00 38.12 ? 836 HOH A O 1 HETATM 8279 O O . HOH O 6 . ? 0.860 -26.561 -32.321 1.00 40.30 ? 837 HOH A O 1 HETATM 8280 O O . HOH O 6 . ? 5.359 7.548 -24.113 1.00 39.39 ? 838 HOH A O 1 HETATM 8281 O O . HOH O 6 . ? -28.406 -7.079 -19.998 1.00 34.86 ? 839 HOH A O 1 HETATM 8282 O O . HOH O 6 . ? 24.728 -7.633 -9.856 1.00 38.55 ? 840 HOH A O 1 HETATM 8283 O O . HOH O 6 . ? -7.258 -15.918 -3.937 1.00 36.96 ? 841 HOH A O 1 HETATM 8284 O O . HOH O 6 . ? -17.748 -1.215 -17.687 1.00 31.91 ? 842 HOH A O 1 HETATM 8285 O O . HOH O 6 . ? -10.792 20.823 -29.858 1.00 68.15 ? 843 HOH A O 1 HETATM 8286 O O . HOH O 6 . ? 8.151 -3.696 -4.181 1.00 37.02 ? 844 HOH A O 1 HETATM 8287 O O . HOH O 6 . ? 20.364 -21.654 -22.867 1.00 69.42 ? 845 HOH A O 1 HETATM 8288 O O . HOH O 6 . ? -15.527 15.008 -27.994 1.00 48.70 ? 846 HOH A O 1 HETATM 8289 O O . HOH O 6 . ? -20.430 3.825 -13.239 1.00 54.35 ? 847 HOH A O 1 HETATM 8290 O O . HOH O 6 . ? -8.366 12.834 -20.851 1.00 47.82 ? 848 HOH A O 1 HETATM 8291 O O . HOH O 6 . ? -3.281 -24.798 -37.151 1.00 36.38 ? 849 HOH A O 1 HETATM 8292 O O . HOH O 6 . ? -13.641 -8.415 -28.458 1.00 31.40 ? 851 HOH A O 1 HETATM 8293 O O . HOH O 6 . ? -1.270 -1.176 -0.350 1.00 43.07 ? 852 HOH A O 1 HETATM 8294 O O . HOH O 6 . ? -28.930 -23.206 -25.319 1.00 33.21 ? 853 HOH A O 1 HETATM 8295 O O . HOH O 6 . ? -16.987 -4.229 -20.218 1.00 54.59 ? 854 HOH A O 1 HETATM 8296 O O . HOH O 6 . ? -11.204 0.334 -10.176 1.00 40.15 ? 855 HOH A O 1 HETATM 8297 O O . HOH O 6 . ? -23.105 -21.330 -3.379 1.00 39.01 ? 856 HOH A O 1 HETATM 8298 O O . HOH O 6 . ? -19.274 3.904 -2.631 1.00 35.35 ? 857 HOH A O 1 HETATM 8299 O O . HOH O 6 . ? -9.401 -21.892 -10.825 1.00 35.22 ? 858 HOH A O 1 HETATM 8300 O O . HOH O 6 . ? -36.439 -4.694 -12.681 1.00 39.38 ? 859 HOH A O 1 HETATM 8301 O O . HOH O 6 . ? -26.092 16.449 -31.187 1.00 44.78 ? 860 HOH A O 1 HETATM 8302 O O . HOH O 6 . ? -21.598 -0.156 -4.024 1.00 32.99 ? 861 HOH A O 1 HETATM 8303 O O . HOH O 6 . ? -18.318 12.338 -7.881 1.00 42.74 ? 862 HOH A O 1 HETATM 8304 O O . HOH O 6 . ? -8.123 -23.836 -36.444 1.00 33.37 ? 863 HOH A O 1 HETATM 8305 O O . HOH O 6 . ? 13.758 -26.408 -15.184 1.00 40.32 ? 864 HOH A O 1 HETATM 8306 O O . HOH O 6 . ? 13.175 -2.211 -24.034 1.00 36.12 ? 865 HOH A O 1 HETATM 8307 O O . HOH O 6 . ? 10.534 -3.090 -6.229 1.00 32.07 ? 866 HOH A O 1 HETATM 8308 O O . HOH O 6 . ? 0.779 12.001 -11.785 1.00 32.73 ? 867 HOH A O 1 HETATM 8309 O O . HOH O 6 . ? -30.746 -23.673 -23.159 1.00 34.80 ? 868 HOH A O 1 HETATM 8310 O O . HOH O 6 . ? -20.336 13.206 -6.373 1.00 49.46 ? 869 HOH A O 1 HETATM 8311 O O . HOH O 6 . ? 20.777 -27.666 -18.449 1.00 46.93 ? 870 HOH A O 1 HETATM 8312 O O . HOH O 6 . ? -18.949 7.737 -5.131 1.00 32.71 ? 871 HOH A O 1 HETATM 8313 O O . HOH O 6 . ? 8.039 -22.924 0.741 1.00 56.25 ? 872 HOH A O 1 HETATM 8314 O O . HOH O 6 . ? 6.784 -2.369 -27.010 1.00 37.15 ? 873 HOH A O 1 HETATM 8315 O O . HOH O 6 . ? 4.287 12.530 -20.598 1.00 38.57 ? 874 HOH A O 1 HETATM 8316 O O . HOH O 6 . ? -3.265 11.531 -39.620 1.00 44.81 ? 875 HOH A O 1 HETATM 8317 O O . HOH O 6 . ? -15.137 -23.443 -7.978 1.00 54.00 ? 876 HOH A O 1 HETATM 8318 O O . HOH O 6 . ? -6.278 14.868 -21.424 1.00 48.53 ? 877 HOH A O 1 HETATM 8319 O O . HOH O 6 . ? -6.368 -17.332 8.636 1.00 40.35 ? 878 HOH A O 1 HETATM 8320 O O . HOH O 6 . ? -34.924 -6.035 -10.733 1.00 43.73 ? 879 HOH A O 1 HETATM 8321 O O . HOH O 6 . ? -2.980 -34.701 -22.891 1.00 51.23 ? 880 HOH A O 1 HETATM 8322 O O . HOH O 6 . ? -28.016 -8.513 -29.084 1.00 39.37 ? 881 HOH A O 1 HETATM 8323 O O . HOH O 6 . ? -5.153 -30.742 -26.974 1.00 40.44 ? 882 HOH A O 1 HETATM 8324 O O . HOH O 6 . ? -28.861 -11.027 -21.364 1.00 42.41 ? 883 HOH A O 1 HETATM 8325 O O . HOH O 6 . ? 18.209 -10.075 -6.105 1.00 39.69 ? 884 HOH A O 1 HETATM 8326 O O . HOH O 6 . ? 13.706 -0.396 -15.371 1.00 23.82 ? 885 HOH A O 1 HETATM 8327 O O . HOH O 6 . ? 24.493 -3.348 -10.001 1.00 41.25 ? 886 HOH A O 1 HETATM 8328 O O . HOH O 6 . ? -4.509 -27.830 -13.889 1.00 44.26 ? 887 HOH A O 1 HETATM 8329 O O . HOH O 6 . ? -25.680 -8.666 -24.851 1.00 34.97 ? 888 HOH A O 1 HETATM 8330 O O . HOH O 6 . ? 6.667 5.648 -25.282 1.00 36.37 ? 889 HOH A O 1 HETATM 8331 O O . HOH O 6 . ? 18.106 7.095 -13.349 1.00 42.14 ? 890 HOH A O 1 HETATM 8332 O O . HOH O 6 . ? 5.571 -13.504 -34.048 1.00 45.70 ? 891 HOH A O 1 HETATM 8333 O O . HOH O 6 . ? 11.342 5.564 -24.987 1.00 42.19 ? 892 HOH A O 1 HETATM 8334 O O . HOH O 6 . ? -35.869 -6.718 -20.070 1.00 48.50 ? 893 HOH A O 1 HETATM 8335 O O . HOH O 6 . ? -16.201 12.471 -17.947 1.00 48.64 ? 894 HOH A O 1 HETATM 8336 O O . HOH O 6 . ? -23.931 -26.170 -19.255 1.00 42.64 ? 895 HOH A O 1 HETATM 8337 O O . HOH O 6 . ? -25.927 -27.546 -4.106 1.00 49.11 ? 896 HOH A O 1 HETATM 8338 O O . HOH P 6 . ? -9.799 -6.979 10.047 1.00 37.31 ? 509 HOH B O 1 HETATM 8339 O O . HOH P 6 . ? 14.941 8.953 11.510 1.00 35.39 ? 510 HOH B O 1 HETATM 8340 O O . HOH P 6 . ? 7.771 5.466 14.124 1.00 18.17 ? 511 HOH B O 1 HETATM 8341 O O . HOH P 6 . ? -25.270 -24.698 2.195 1.00 39.70 ? 512 HOH B O 1 HETATM 8342 O O . HOH P 6 . ? -18.277 -1.085 11.181 1.00 35.34 ? 513 HOH B O 1 HETATM 8343 O O . HOH P 6 . ? -1.463 5.223 -2.376 1.00 9.56 ? 514 HOH B O 1 HETATM 8344 O O . HOH P 6 . ? 20.074 18.129 10.054 1.00 39.82 ? 515 HOH B O 1 HETATM 8345 O O . HOH P 6 . ? 24.236 -1.075 32.217 1.00 37.84 ? 516 HOH B O 1 HETATM 8346 O O . HOH P 6 . ? 14.181 4.727 9.639 1.00 14.97 ? 517 HOH B O 1 HETATM 8347 O O . HOH P 6 . ? -0.458 2.909 20.852 1.00 14.59 ? 518 HOH B O 1 HETATM 8348 O O . HOH P 6 . ? 11.705 4.656 0.014 1.00 15.95 ? 519 HOH B O 1 HETATM 8349 O O . HOH P 6 . ? -5.860 21.419 6.230 1.00 20.50 ? 520 HOH B O 1 HETATM 8350 O O . HOH P 6 . ? -0.587 5.357 22.547 1.00 15.23 ? 521 HOH B O 1 HETATM 8351 O O . HOH P 6 . ? 3.331 10.121 12.456 1.00 17.44 ? 522 HOH B O 1 HETATM 8352 O O . HOH P 6 . ? -7.114 -10.935 18.416 1.00 43.81 ? 523 HOH B O 1 HETATM 8353 O O . HOH P 6 . ? -0.388 -0.950 40.993 1.00 58.32 ? 524 HOH B O 1 HETATM 8354 O O . HOH P 6 . ? 30.354 8.114 6.975 1.00 51.90 ? 525 HOH B O 1 HETATM 8355 O O . HOH P 6 . ? 27.887 17.185 32.965 1.00 43.15 ? 526 HOH B O 1 HETATM 8356 O O . HOH P 6 . ? 8.749 -1.647 1.578 1.00 18.31 ? 527 HOH B O 1 HETATM 8357 O O . HOH P 6 . ? -2.489 21.972 -2.008 1.00 45.95 ? 528 HOH B O 1 HETATM 8358 O O . HOH P 6 . ? -24.718 2.218 13.829 1.00 34.06 ? 529 HOH B O 1 HETATM 8359 O O . HOH P 6 . ? 16.995 -4.384 23.092 1.00 21.03 ? 530 HOH B O 1 HETATM 8360 O O . HOH P 6 . ? 5.407 -3.709 3.845 1.00 17.30 ? 531 HOH B O 1 HETATM 8361 O O . HOH P 6 . ? 11.246 24.420 33.075 1.00 37.58 ? 532 HOH B O 1 HETATM 8362 O O . HOH P 6 . ? 22.602 0.155 33.763 1.00 46.35 ? 533 HOH B O 1 HETATM 8363 O O . HOH P 6 . ? 14.025 6.093 3.841 1.00 23.74 ? 534 HOH B O 1 HETATM 8364 O O . HOH P 6 . ? 9.141 21.281 17.958 1.00 20.72 ? 535 HOH B O 1 HETATM 8365 O O . HOH P 6 . ? 4.875 1.427 9.570 1.00 18.27 ? 536 HOH B O 1 HETATM 8366 O O . HOH P 6 . ? 4.925 10.719 -3.159 1.00 34.96 ? 537 HOH B O 1 HETATM 8367 O O . HOH P 6 . ? 15.377 -0.341 28.274 1.00 24.11 ? 538 HOH B O 1 HETATM 8368 O O . HOH P 6 . ? -6.417 23.529 10.364 1.00 42.67 ? 539 HOH B O 1 HETATM 8369 O O . HOH P 6 . ? 16.895 28.862 33.456 1.00 40.36 ? 540 HOH B O 1 HETATM 8370 O O . HOH P 6 . ? -6.785 16.786 -1.546 1.00 37.41 ? 541 HOH B O 1 HETATM 8371 O O . HOH P 6 . ? -14.187 -3.209 33.937 1.00 62.69 ? 542 HOH B O 1 HETATM 8372 O O . HOH P 6 . ? -15.501 -7.226 6.535 1.00 21.73 ? 543 HOH B O 1 HETATM 8373 O O . HOH P 6 . ? 23.130 -1.085 29.126 1.00 38.12 ? 544 HOH B O 1 HETATM 8374 O O . HOH P 6 . ? 21.168 6.212 -2.034 1.00 47.13 ? 545 HOH B O 1 HETATM 8375 O O . HOH P 6 . ? 21.952 10.094 4.119 1.00 42.90 ? 546 HOH B O 1 HETATM 8376 O O . HOH P 6 . ? -20.882 -20.276 11.382 1.00 39.88 ? 547 HOH B O 1 HETATM 8377 O O . HOH P 6 . ? -18.241 -9.017 11.610 1.00 39.46 ? 548 HOH B O 1 HETATM 8378 O O . HOH P 6 . ? 3.082 5.135 21.515 1.00 15.72 ? 549 HOH B O 1 HETATM 8379 O O . HOH P 6 . ? 18.144 39.751 13.622 1.00 180.07 ? 551 HOH B O 1 HETATM 8380 O O . HOH P 6 . ? -12.166 -2.862 8.672 1.00 20.05 ? 552 HOH B O 1 HETATM 8381 O O . HOH P 6 . ? -21.960 -9.095 5.973 1.00 43.52 ? 553 HOH B O 1 HETATM 8382 O O . HOH P 6 . ? 1.818 27.139 0.734 1.00 41.49 ? 554 HOH B O 1 HETATM 8383 O O . HOH P 6 . ? 7.998 8.201 7.627 1.00 16.15 ? 555 HOH B O 1 HETATM 8384 O O . HOH P 6 . ? -10.267 10.433 30.346 1.00 25.01 ? 556 HOH B O 1 HETATM 8385 O O . HOH P 6 . ? 9.786 9.787 -4.516 1.00 16.69 ? 557 HOH B O 1 HETATM 8386 O O . HOH P 6 . ? 3.053 9.762 38.408 1.00 45.84 ? 558 HOH B O 1 HETATM 8387 O O . HOH P 6 . ? -11.237 9.285 -1.220 1.00 21.21 ? 559 HOH B O 1 HETATM 8388 O O . HOH P 6 . ? 13.937 23.569 5.238 1.00 50.67 ? 560 HOH B O 1 HETATM 8389 O O . HOH P 6 . ? -17.150 -9.415 20.270 1.00 37.33 ? 561 HOH B O 1 HETATM 8390 O O . HOH P 6 . ? -23.789 10.925 3.563 1.00 43.06 ? 562 HOH B O 1 HETATM 8391 O O . HOH P 6 . ? 29.064 5.658 33.331 1.00 26.92 ? 563 HOH B O 1 HETATM 8392 O O . HOH P 6 . ? 5.331 3.989 10.738 1.00 12.65 ? 564 HOH B O 1 HETATM 8393 O O . HOH P 6 . ? -17.051 14.866 9.848 1.00 40.81 ? 565 HOH B O 1 HETATM 8394 O O . HOH P 6 . ? 21.437 -4.564 5.206 1.00 20.29 ? 566 HOH B O 1 HETATM 8395 O O . HOH P 6 . ? 16.563 11.722 17.357 1.00 23.49 ? 567 HOH B O 1 HETATM 8396 O O . HOH P 6 . ? 17.645 0.689 10.019 1.00 16.39 ? 568 HOH B O 1 HETATM 8397 O O . HOH P 6 . ? -20.203 -7.659 7.694 1.00 40.77 ? 569 HOH B O 1 HETATM 8398 O O . HOH P 6 . ? 0.930 -1.257 0.811 1.00 39.59 ? 570 HOH B O 1 HETATM 8399 O O . HOH P 6 . ? 4.792 15.422 -1.634 1.00 18.68 ? 571 HOH B O 1 HETATM 8400 O O . HOH P 6 . ? -4.231 12.619 5.876 1.00 15.03 ? 572 HOH B O 1 HETATM 8401 O O . HOH P 6 . ? -9.037 -9.804 10.554 1.00 15.83 ? 573 HOH B O 1 HETATM 8402 O O . HOH P 6 . ? -23.556 9.706 6.529 1.00 32.21 ? 574 HOH B O 1 HETATM 8403 O O . HOH P 6 . ? 24.276 22.434 20.024 1.00 41.85 ? 575 HOH B O 1 HETATM 8404 O O . HOH P 6 . ? 23.668 0.301 36.580 1.00 45.41 ? 576 HOH B O 1 HETATM 8405 O O . HOH P 6 . ? 17.652 13.079 11.427 1.00 41.26 ? 577 HOH B O 1 HETATM 8406 O O . HOH P 6 . ? 2.198 11.437 0.273 1.00 16.47 ? 578 HOH B O 1 HETATM 8407 O O . HOH P 6 . ? 4.188 -11.358 3.101 1.00 37.59 ? 579 HOH B O 1 HETATM 8408 O O . HOH P 6 . ? 30.822 3.722 32.726 1.00 39.48 ? 580 HOH B O 1 HETATM 8409 O O . HOH P 6 . ? 3.945 22.998 14.465 1.00 20.96 ? 581 HOH B O 1 HETATM 8410 O O . HOH P 6 . ? 1.272 19.633 43.305 1.00 39.49 ? 582 HOH B O 1 HETATM 8411 O O . HOH P 6 . ? 10.981 7.700 21.158 1.00 15.40 ? 583 HOH B O 1 HETATM 8412 O O . HOH P 6 . ? 19.504 -7.359 -2.331 1.00 39.69 ? 584 HOH B O 1 HETATM 8413 O O . HOH P 6 . ? -18.527 16.903 11.932 1.00 49.40 ? 585 HOH B O 1 HETATM 8414 O O . HOH P 6 . ? 21.262 -4.152 7.816 1.00 19.49 ? 586 HOH B O 1 HETATM 8415 O O . HOH P 6 . ? 31.275 3.322 8.140 1.00 50.46 ? 587 HOH B O 1 HETATM 8416 O O . HOH P 6 . ? -0.424 -6.900 23.204 1.00 36.83 ? 588 HOH B O 1 HETATM 8417 O O . HOH P 6 . ? -16.204 -10.262 22.994 1.00 56.24 ? 589 HOH B O 1 HETATM 8418 O O . HOH P 6 . ? 16.726 5.779 10.491 1.00 15.54 ? 590 HOH B O 1 HETATM 8419 O O . HOH P 6 . ? -5.697 5.685 -3.726 1.00 21.15 ? 591 HOH B O 1 HETATM 8420 O O . HOH P 6 . ? 23.759 12.105 18.969 1.00 25.04 ? 592 HOH B O 1 HETATM 8421 O O . HOH P 6 . ? 29.254 10.117 33.198 1.00 53.80 ? 593 HOH B O 1 HETATM 8422 O O . HOH P 6 . ? 20.501 -3.566 -1.898 1.00 22.01 ? 594 HOH B O 1 HETATM 8423 O O . HOH P 6 . ? -21.244 -2.104 20.853 1.00 22.92 ? 595 HOH B O 1 HETATM 8424 O O . HOH P 6 . ? 4.784 15.614 1.350 1.00 21.65 ? 596 HOH B O 1 HETATM 8425 O O . HOH P 6 . ? 29.094 32.836 14.050 1.00 53.84 ? 597 HOH B O 1 HETATM 8426 O O . HOH P 6 . ? 3.325 41.294 14.536 1.00 51.39 ? 598 HOH B O 1 HETATM 8427 O O . HOH P 6 . ? -16.197 15.702 -4.218 1.00 35.17 ? 599 HOH B O 1 HETATM 8428 O O . HOH P 6 . ? 29.674 -5.024 8.921 1.00 38.22 ? 600 HOH B O 1 HETATM 8429 O O . HOH P 6 . ? 15.516 -9.537 1.598 1.00 21.76 ? 601 HOH B O 1 HETATM 8430 O O . HOH P 6 . ? 4.445 -3.551 7.222 1.00 21.08 ? 602 HOH B O 1 HETATM 8431 O O . HOH P 6 . ? 8.548 35.172 27.369 1.00 47.07 ? 603 HOH B O 1 HETATM 8432 O O . HOH P 6 . ? -0.905 13.145 16.355 1.00 16.66 ? 604 HOH B O 1 HETATM 8433 O O . HOH P 6 . ? -18.074 14.420 12.180 1.00 54.70 ? 605 HOH B O 1 HETATM 8434 O O . HOH P 6 . ? 20.034 1.404 5.258 1.00 20.49 ? 606 HOH B O 1 HETATM 8435 O O . HOH P 6 . ? 3.263 7.141 -2.818 1.00 20.87 ? 607 HOH B O 1 HETATM 8436 O O . HOH P 6 . ? 18.180 2.284 13.151 1.00 22.72 ? 608 HOH B O 1 HETATM 8437 O O . HOH P 6 . ? 5.647 50.884 5.977 1.00 58.51 ? 609 HOH B O 1 HETATM 8438 O O . HOH P 6 . ? -14.784 -8.649 18.878 1.00 32.16 ? 610 HOH B O 1 HETATM 8439 O O . HOH P 6 . ? -20.625 -0.712 3.579 1.00 26.85 ? 611 HOH B O 1 HETATM 8440 O O . HOH P 6 . ? 36.412 6.899 11.599 1.00 44.04 ? 612 HOH B O 1 HETATM 8441 O O . HOH P 6 . ? 16.599 27.988 5.721 1.00 41.58 ? 613 HOH B O 1 HETATM 8442 O O . HOH P 6 . ? 2.981 -3.663 41.106 1.00 39.72 ? 614 HOH B O 1 HETATM 8443 O O . HOH P 6 . ? -8.016 12.938 36.664 1.00 33.50 ? 615 HOH B O 1 HETATM 8444 O O . HOH P 6 . ? 24.316 19.124 26.822 1.00 25.27 ? 616 HOH B O 1 HETATM 8445 O O . HOH P 6 . ? -12.816 -6.885 15.837 1.00 29.27 ? 617 HOH B O 1 HETATM 8446 O O . HOH P 6 . ? 33.899 14.620 16.918 1.00 49.38 ? 618 HOH B O 1 HETATM 8447 O O . HOH P 6 . ? 2.305 13.264 13.583 1.00 22.17 ? 619 HOH B O 1 HETATM 8448 O O . HOH P 6 . ? 20.719 17.872 24.512 1.00 25.36 ? 620 HOH B O 1 HETATM 8449 O O . HOH P 6 . ? 4.476 -5.842 30.534 1.00 48.84 ? 621 HOH B O 1 HETATM 8450 O O . HOH P 6 . ? -14.688 12.484 6.345 1.00 47.09 ? 622 HOH B O 1 HETATM 8451 O O . HOH P 6 . ? -11.457 13.903 -3.728 1.00 47.56 ? 623 HOH B O 1 HETATM 8452 O O . HOH P 6 . ? 30.264 13.873 32.035 1.00 48.69 ? 624 HOH B O 1 HETATM 8453 O O . HOH P 6 . ? 9.656 -9.743 0.054 1.00 20.60 ? 625 HOH B O 1 HETATM 8454 O O . HOH P 6 . ? -3.421 8.070 28.748 1.00 21.07 ? 626 HOH B O 1 HETATM 8455 O O . HOH P 6 . ? 6.063 14.080 42.569 1.00 50.22 ? 627 HOH B O 1 HETATM 8456 O O . HOH P 6 . ? -17.148 12.318 5.923 1.00 26.86 ? 628 HOH B O 1 HETATM 8457 O O . HOH P 6 . ? 9.453 25.263 34.739 1.00 53.37 ? 629 HOH B O 1 HETATM 8458 O O . HOH P 6 . ? -14.637 16.081 8.661 1.00 51.45 ? 630 HOH B O 1 HETATM 8459 O O . HOH P 6 . ? 3.314 19.628 17.740 1.00 27.15 ? 631 HOH B O 1 HETATM 8460 O O . HOH P 6 . ? 20.568 18.372 13.538 1.00 39.28 ? 632 HOH B O 1 HETATM 8461 O O . HOH P 6 . ? -0.612 12.152 0.315 1.00 18.88 ? 633 HOH B O 1 HETATM 8462 O O . HOH P 6 . ? -24.173 1.317 32.628 1.00 55.22 ? 634 HOH B O 1 HETATM 8463 O O . HOH P 6 . ? -11.251 -5.172 17.349 1.00 28.70 ? 635 HOH B O 1 HETATM 8464 O O . HOH P 6 . ? 32.005 30.836 29.457 1.00 57.15 ? 636 HOH B O 1 HETATM 8465 O O . HOH P 6 . ? -8.871 9.630 36.474 1.00 43.71 ? 637 HOH B O 1 HETATM 8466 O O . HOH P 6 . ? -2.604 17.662 -1.363 1.00 19.35 ? 638 HOH B O 1 HETATM 8467 O O . HOH P 6 . ? 25.732 17.146 24.948 1.00 29.13 ? 639 HOH B O 1 HETATM 8468 O O . HOH P 6 . ? 3.388 9.755 -1.536 1.00 23.79 ? 640 HOH B O 1 HETATM 8469 O O . HOH P 6 . ? -27.305 16.617 16.173 1.00 37.80 ? 641 HOH B O 1 HETATM 8470 O O . HOH P 6 . ? 31.315 3.020 28.237 1.00 29.23 ? 642 HOH B O 1 HETATM 8471 O O . HOH P 6 . ? 6.748 -9.826 -2.892 1.00 20.09 ? 643 HOH B O 1 HETATM 8472 O O . HOH P 6 . ? -25.957 12.515 23.300 1.00 32.22 ? 644 HOH B O 1 HETATM 8473 O O . HOH P 6 . ? -3.796 -1.465 -0.316 1.00 18.64 ? 645 HOH B O 1 HETATM 8474 O O . HOH P 6 . ? -2.298 15.220 36.853 1.00 26.72 ? 646 HOH B O 1 HETATM 8475 O O . HOH P 6 . ? 10.804 9.055 3.017 1.00 27.10 ? 647 HOH B O 1 HETATM 8476 O O . HOH P 6 . ? -3.988 16.172 19.081 1.00 25.31 ? 648 HOH B O 1 HETATM 8477 O O . HOH P 6 . ? -9.668 -16.063 14.850 1.00 41.63 ? 649 HOH B O 1 HETATM 8478 O O . HOH P 6 . ? -23.036 -0.319 34.071 1.00 48.81 ? 651 HOH B O 1 HETATM 8479 O O . HOH P 6 . ? 15.894 2.711 31.990 1.00 52.76 ? 652 HOH B O 1 HETATM 8480 O O . HOH P 6 . ? -10.975 7.648 -3.188 1.00 26.74 ? 653 HOH B O 1 HETATM 8481 O O . HOH P 6 . ? -21.214 5.243 -4.011 1.00 49.13 ? 654 HOH B O 1 HETATM 8482 O O . HOH P 6 . ? -5.321 -8.052 19.508 1.00 29.72 ? 655 HOH B O 1 HETATM 8483 O O . HOH P 6 . ? -1.942 19.063 22.986 1.00 28.45 ? 656 HOH B O 1 HETATM 8484 O O . HOH P 6 . ? 14.396 -8.414 19.887 1.00 38.70 ? 657 HOH B O 1 HETATM 8485 O O . HOH P 6 . ? -9.626 12.161 32.333 1.00 54.19 ? 658 HOH B O 1 HETATM 8486 O O . HOH P 6 . ? 7.411 9.180 -3.762 1.00 43.33 ? 659 HOH B O 1 HETATM 8487 O O . HOH P 6 . ? 7.107 -7.023 14.901 1.00 36.92 ? 660 HOH B O 1 HETATM 8488 O O . HOH P 6 . ? -4.727 13.715 41.182 1.00 39.64 ? 661 HOH B O 1 HETATM 8489 O O . HOH P 6 . ? 1.160 -10.650 12.050 1.00 25.76 ? 662 HOH B O 1 HETATM 8490 O O . HOH P 6 . ? 11.344 -7.579 24.552 1.00 52.96 ? 663 HOH B O 1 HETATM 8491 O O . HOH P 6 . ? 19.281 22.200 33.658 1.00 28.56 ? 664 HOH B O 1 HETATM 8492 O O . HOH P 6 . ? 3.748 7.134 38.792 1.00 50.83 ? 665 HOH B O 1 HETATM 8493 O O . HOH P 6 . ? 14.371 38.630 20.327 1.00 37.69 ? 666 HOH B O 1 HETATM 8494 O O . HOH P 6 . ? 11.129 8.391 5.581 1.00 32.71 ? 667 HOH B O 1 HETATM 8495 O O . HOH P 6 . ? -8.665 -3.432 11.780 1.00 33.65 ? 668 HOH B O 1 HETATM 8496 O O . HOH P 6 . ? -0.217 -11.509 14.446 1.00 57.41 ? 669 HOH B O 1 HETATM 8497 O O . HOH P 6 . ? 20.384 -5.516 22.383 1.00 27.79 ? 670 HOH B O 1 HETATM 8498 O O . HOH P 6 . ? 25.281 -11.763 17.663 1.00 54.73 ? 671 HOH B O 1 HETATM 8499 O O . HOH P 6 . ? 32.167 7.469 24.324 1.00 36.40 ? 672 HOH B O 1 HETATM 8500 O O . HOH P 6 . ? 11.058 49.968 4.988 1.00 44.03 ? 673 HOH B O 1 HETATM 8501 O O . HOH P 6 . ? -19.308 -7.414 25.394 1.00 31.84 ? 674 HOH B O 1 HETATM 8502 O O . HOH P 6 . ? 12.749 7.714 1.822 1.00 24.80 ? 675 HOH B O 1 HETATM 8503 O O . HOH P 6 . ? 7.091 0.808 41.423 1.00 41.59 ? 676 HOH B O 1 HETATM 8504 O O . HOH P 6 . ? -15.885 6.499 35.819 1.00 51.12 ? 677 HOH B O 1 HETATM 8505 O O . HOH P 6 . ? 28.145 30.189 31.514 1.00 36.89 ? 678 HOH B O 1 HETATM 8506 O O . HOH P 6 . ? -10.919 -8.755 27.957 1.00 33.74 ? 679 HOH B O 1 HETATM 8507 O O . HOH P 6 . ? 26.355 -13.940 23.110 1.00 40.38 ? 680 HOH B O 1 HETATM 8508 O O . HOH P 6 . ? -7.470 -4.460 31.500 1.00 48.49 ? 681 HOH B O 1 HETATM 8509 O O . HOH P 6 . ? 5.689 5.585 39.337 1.00 56.26 ? 682 HOH B O 1 HETATM 8510 O O . HOH P 6 . ? 18.213 16.248 23.391 1.00 22.72 ? 683 HOH B O 1 HETATM 8511 O O . HOH P 6 . ? -17.109 -7.948 24.249 1.00 32.34 ? 684 HOH B O 1 HETATM 8512 O O . HOH P 6 . ? -22.397 -13.695 6.814 1.00 30.09 ? 685 HOH B O 1 HETATM 8513 O O . HOH P 6 . ? -17.518 14.314 19.188 1.00 43.43 ? 686 HOH B O 1 HETATM 8514 O O . HOH P 6 . ? -4.400 15.291 38.653 1.00 35.56 ? 687 HOH B O 1 HETATM 8515 O O . HOH P 6 . ? 10.700 47.618 5.238 1.00 49.31 ? 688 HOH B O 1 HETATM 8516 O O . HOH P 6 . ? -20.095 -14.085 11.662 1.00 30.10 ? 689 HOH B O 1 HETATM 8517 O O . HOH P 6 . ? 20.939 28.797 32.172 1.00 33.70 ? 690 HOH B O 1 HETATM 8518 O O . HOH P 6 . ? -16.502 -3.731 14.187 1.00 27.22 ? 691 HOH B O 1 HETATM 8519 O O . HOH P 6 . ? -20.768 -7.243 29.196 1.00 46.50 ? 692 HOH B O 1 HETATM 8520 O O . HOH P 6 . ? -9.108 14.358 34.019 1.00 54.00 ? 693 HOH B O 1 HETATM 8521 O O . HOH P 6 . ? 18.662 6.912 37.222 1.00 34.76 ? 694 HOH B O 1 HETATM 8522 O O . HOH P 6 . ? 35.060 18.040 18.209 1.00 54.62 ? 695 HOH B O 1 HETATM 8523 O O . HOH P 6 . ? 2.856 18.022 19.968 1.00 30.07 ? 696 HOH B O 1 HETATM 8524 O O . HOH P 6 . ? -19.145 -7.971 19.256 1.00 51.91 ? 697 HOH B O 1 HETATM 8525 O O . HOH P 6 . ? 18.600 14.585 13.788 1.00 40.58 ? 698 HOH B O 1 HETATM 8526 O O . HOH P 6 . ? -14.044 -8.998 8.049 1.00 32.76 ? 699 HOH B O 1 HETATM 8527 O O . HOH P 6 . ? 13.007 10.848 34.241 1.00 55.08 ? 700 HOH B O 1 HETATM 8528 O O . HOH P 6 . ? 5.270 2.447 40.343 1.00 49.60 ? 701 HOH B O 1 HETATM 8529 O O . HOH P 6 . ? 5.506 42.385 16.576 1.00 45.04 ? 702 HOH B O 1 HETATM 8530 O O . HOH P 6 . ? 8.113 -4.701 27.855 1.00 46.39 ? 703 HOH B O 1 HETATM 8531 O O . HOH P 6 . ? 26.233 42.921 22.024 1.00 51.55 ? 704 HOH B O 1 HETATM 8532 O O . HOH P 6 . ? 25.810 32.025 23.353 1.00 29.47 ? 705 HOH B O 1 HETATM 8533 O O . HOH P 6 . ? -15.151 -6.332 17.363 1.00 25.47 ? 706 HOH B O 1 HETATM 8534 O O . HOH P 6 . ? 6.880 10.925 -5.776 1.00 57.25 ? 707 HOH B O 1 HETATM 8535 O O . HOH P 6 . ? 9.903 -17.074 11.037 1.00 31.85 ? 708 HOH B O 1 HETATM 8536 O O . HOH P 6 . ? 20.547 23.624 35.484 1.00 42.64 ? 709 HOH B O 1 HETATM 8537 O O . HOH P 6 . ? 5.596 30.430 34.675 1.00 45.43 ? 710 HOH B O 1 HETATM 8538 O O . HOH P 6 . ? -11.547 22.966 10.613 1.00 40.26 ? 711 HOH B O 1 HETATM 8539 O O . HOH P 6 . ? 5.062 26.344 28.120 1.00 37.11 ? 712 HOH B O 1 HETATM 8540 O O . HOH P 6 . ? 9.377 -3.247 26.165 1.00 29.79 ? 713 HOH B O 1 HETATM 8541 O O . HOH P 6 . ? 10.513 10.727 34.367 1.00 33.58 ? 714 HOH B O 1 HETATM 8542 O O . HOH P 6 . ? 20.092 27.275 14.373 1.00 25.73 ? 715 HOH B O 1 HETATM 8543 O O . HOH P 6 . ? 0.949 -5.207 3.655 1.00 25.21 ? 716 HOH B O 1 HETATM 8544 O O . HOH P 6 . ? 9.066 -4.567 23.837 1.00 30.99 ? 717 HOH B O 1 HETATM 8545 O O . HOH P 6 . ? 18.501 12.579 2.840 1.00 33.82 ? 718 HOH B O 1 HETATM 8546 O O . HOH P 6 . ? 13.347 2.318 31.201 1.00 54.83 ? 719 HOH B O 1 HETATM 8547 O O . HOH P 6 . ? 18.143 24.790 36.405 1.00 47.24 ? 720 HOH B O 1 HETATM 8548 O O . HOH P 6 . ? 7.696 26.008 28.784 1.00 27.79 ? 721 HOH B O 1 HETATM 8549 O O . HOH P 6 . ? -23.231 -6.102 27.507 1.00 60.39 ? 722 HOH B O 1 HETATM 8550 O O . HOH P 6 . ? -6.005 -12.440 20.540 1.00 56.17 ? 723 HOH B O 1 HETATM 8551 O O . HOH P 6 . ? 5.834 32.718 32.934 1.00 44.58 ? 724 HOH B O 1 HETATM 8552 O O . HOH P 6 . ? 15.082 32.451 27.700 1.00 37.19 ? 725 HOH B O 1 HETATM 8553 O O . HOH P 6 . ? 13.854 -7.552 6.975 1.00 20.01 ? 726 HOH B O 1 HETATM 8554 O O . HOH P 6 . ? 23.390 -5.016 23.454 1.00 27.85 ? 727 HOH B O 1 HETATM 8555 O O . HOH P 6 . ? 9.873 29.381 4.069 1.00 49.91 ? 728 HOH B O 1 HETATM 8556 O O . HOH P 6 . ? -11.962 16.868 22.338 1.00 47.06 ? 729 HOH B O 1 HETATM 8557 O O . HOH P 6 . ? 11.210 -11.321 23.491 1.00 44.11 ? 730 HOH B O 1 HETATM 8558 O O . HOH P 6 . ? -20.903 -1.503 32.749 1.00 37.89 ? 731 HOH B O 1 HETATM 8559 O O . HOH P 6 . ? 17.975 41.178 22.697 1.00 58.66 ? 732 HOH B O 1 HETATM 8560 O O . HOH P 6 . ? -18.527 -2.912 13.139 1.00 43.84 ? 733 HOH B O 1 HETATM 8561 O O . HOH P 6 . ? 17.090 21.144 35.059 1.00 37.25 ? 734 HOH B O 1 HETATM 8562 O O . HOH P 6 . ? 38.145 15.319 15.864 1.00 48.98 ? 735 HOH B O 1 HETATM 8563 O O . HOH P 6 . ? 11.752 -3.013 27.656 1.00 31.02 ? 736 HOH B O 1 HETATM 8564 O O . HOH P 6 . ? -7.859 -15.671 16.658 1.00 57.16 ? 737 HOH B O 1 HETATM 8565 O O . HOH P 6 . ? 0.193 -3.985 1.739 1.00 26.46 ? 738 HOH B O 1 HETATM 8566 O O . HOH P 6 . ? -20.503 11.122 32.023 1.00 64.26 ? 739 HOH B O 1 HETATM 8567 O O . HOH P 6 . ? 19.544 15.841 39.063 1.00 55.43 ? 740 HOH B O 1 HETATM 8568 O O . HOH P 6 . ? -17.562 -3.375 16.938 1.00 28.00 ? 741 HOH B O 1 HETATM 8569 O O . HOH P 6 . ? 9.622 -4.145 29.684 1.00 57.35 ? 742 HOH B O 1 HETATM 8570 O O . HOH P 6 . ? 28.268 -1.002 30.672 1.00 42.44 ? 743 HOH B O 1 HETATM 8571 O O . HOH P 6 . ? 28.265 19.644 31.205 1.00 43.66 ? 744 HOH B O 1 HETATM 8572 O O . HOH P 6 . ? -8.573 -3.668 14.688 1.00 31.76 ? 745 HOH B O 1 HETATM 8573 O O . HOH P 6 . ? 34.774 5.853 24.449 1.00 38.11 ? 746 HOH B O 1 HETATM 8574 O O . HOH P 6 . ? 20.143 -11.197 1.254 1.00 26.13 ? 747 HOH B O 1 HETATM 8575 O O . HOH P 6 . ? 3.338 13.926 41.852 1.00 34.21 ? 748 HOH B O 1 HETATM 8576 O O . HOH P 6 . ? -23.041 12.772 24.709 1.00 40.20 ? 749 HOH B O 1 HETATM 8577 O O . HOH P 6 . ? -23.248 -2.213 19.268 1.00 43.17 ? 751 HOH B O 1 HETATM 8578 O O . HOH P 6 . ? 6.827 25.414 4.899 1.00 46.84 ? 752 HOH B O 1 HETATM 8579 O O . HOH P 6 . ? 16.673 8.055 -1.375 1.00 25.45 ? 753 HOH B O 1 HETATM 8580 O O . HOH P 6 . ? -20.604 -16.424 13.616 1.00 33.91 ? 754 HOH B O 1 HETATM 8581 O O . HOH P 6 . ? -22.119 6.238 0.645 1.00 30.80 ? 755 HOH B O 1 HETATM 8582 O O . HOH P 6 . ? -6.332 -0.048 -0.109 1.00 36.33 ? 756 HOH B O 1 HETATM 8583 O O . HOH P 6 . ? 34.958 3.732 20.966 1.00 53.21 ? 757 HOH B O 1 HETATM 8584 O O . HOH P 6 . ? -6.299 -12.249 22.961 1.00 54.16 ? 758 HOH B O 1 HETATM 8585 O O . HOH P 6 . ? 23.339 31.369 29.915 1.00 40.36 ? 759 HOH B O 1 HETATM 8586 O O . HOH P 6 . ? -5.683 -8.629 23.726 1.00 37.31 ? 760 HOH B O 1 HETATM 8587 O O . HOH P 6 . ? -16.550 13.485 3.602 1.00 31.51 ? 761 HOH B O 1 HETATM 8588 O O . HOH P 6 . ? 14.234 7.144 6.800 1.00 28.40 ? 762 HOH B O 1 HETATM 8589 O O . HOH P 6 . ? -4.905 15.246 30.890 1.00 32.49 ? 763 HOH B O 1 HETATM 8590 O O . HOH P 6 . ? -6.490 8.630 36.822 1.00 27.87 ? 764 HOH B O 1 HETATM 8591 O O . HOH P 6 . ? 0.016 -9.732 4.895 1.00 37.62 ? 765 HOH B O 1 HETATM 8592 O O . HOH P 6 . ? 8.678 -4.572 38.784 1.00 37.33 ? 766 HOH B O 1 HETATM 8593 O O . HOH P 6 . ? -15.557 -9.453 10.407 1.00 22.53 ? 767 HOH B O 1 HETATM 8594 O O . HOH P 6 . ? -3.310 17.365 -5.392 1.00 49.72 ? 768 HOH B O 1 HETATM 8595 O O . HOH P 6 . ? -3.169 -1.492 3.090 1.00 39.32 ? 769 HOH B O 1 HETATM 8596 O O . HOH P 6 . ? 3.833 24.976 21.358 1.00 51.04 ? 770 HOH B O 1 HETATM 8597 O O . HOH P 6 . ? -12.147 5.353 -2.874 1.00 35.36 ? 771 HOH B O 1 HETATM 8598 O O . HOH P 6 . ? -0.925 16.440 -2.615 1.00 33.28 ? 772 HOH B O 1 HETATM 8599 O O . HOH P 6 . ? -3.080 8.975 -3.833 1.00 35.18 ? 773 HOH B O 1 HETATM 8600 O O . HOH P 6 . ? -19.611 -18.476 13.002 1.00 32.94 ? 774 HOH B O 1 HETATM 8601 O O . HOH P 6 . ? -5.478 17.691 22.274 1.00 32.79 ? 775 HOH B O 1 HETATM 8602 O O . HOH P 6 . ? 30.100 2.264 30.388 1.00 46.56 ? 776 HOH B O 1 HETATM 8603 O O . HOH P 6 . ? -12.889 6.287 36.696 1.00 36.02 ? 777 HOH B O 1 HETATM 8604 O O . HOH P 6 . ? -12.875 11.345 37.142 1.00 55.84 ? 778 HOH B O 1 HETATM 8605 O O . HOH P 6 . ? 1.500 31.653 19.296 1.00 57.97 ? 779 HOH B O 1 HETATM 8606 O O . HOH P 6 . ? -3.193 13.907 43.361 1.00 34.76 ? 780 HOH B O 1 HETATM 8607 O O . HOH P 6 . ? 28.991 36.078 22.703 1.00 46.75 ? 781 HOH B O 1 HETATM 8608 O O . HOH P 6 . ? 9.818 12.580 -9.046 1.00 35.99 ? 782 HOH B O 1 HETATM 8609 O O . HOH P 6 . ? -7.890 0.230 2.991 1.00 35.05 ? 783 HOH B O 1 HETATM 8610 O O . HOH P 6 . ? -4.496 15.855 -0.819 1.00 34.82 ? 784 HOH B O 1 HETATM 8611 O O . HOH P 6 . ? 28.400 -13.117 24.003 1.00 44.00 ? 785 HOH B O 1 HETATM 8612 O O . HOH P 6 . ? -24.554 -1.652 26.418 1.00 48.33 ? 786 HOH B O 1 HETATM 8613 O O . HOH P 6 . ? -24.087 -16.022 6.661 1.00 31.23 ? 787 HOH B O 1 HETATM 8614 O O . HOH P 6 . ? 28.124 33.415 23.511 1.00 52.01 ? 788 HOH B O 1 HETATM 8615 O O . HOH P 6 . ? -13.534 -1.138 31.424 1.00 52.88 ? 789 HOH B O 1 HETATM 8616 O O . HOH P 6 . ? -22.623 10.775 20.776 1.00 37.66 ? 790 HOH B O 1 HETATM 8617 O O . HOH P 6 . ? -22.057 6.510 -1.883 1.00 52.66 ? 791 HOH B O 1 HETATM 8618 O O . HOH P 6 . ? 34.840 4.480 10.885 1.00 39.55 ? 792 HOH B O 1 HETATM 8619 O O . HOH P 6 . ? 9.962 16.112 42.688 1.00 46.77 ? 793 HOH B O 1 HETATM 8620 O O . HOH P 6 . ? -24.243 5.641 11.329 1.00 26.11 ? 794 HOH B O 1 HETATM 8621 O O . HOH P 6 . ? 6.982 34.504 34.491 1.00 46.52 ? 795 HOH B O 1 HETATM 8622 O O . HOH P 6 . ? -17.054 5.326 -2.910 1.00 35.96 ? 796 HOH B O 1 HETATM 8623 O O . HOH P 6 . ? -18.610 -11.663 12.941 1.00 34.33 ? 797 HOH B O 1 HETATM 8624 O O . HOH P 6 . ? 5.856 9.545 38.064 1.00 48.31 ? 798 HOH B O 1 HETATM 8625 O O . HOH P 6 . ? -5.514 -1.418 38.761 1.00 45.20 ? 799 HOH B O 1 HETATM 8626 O O . HOH P 6 . ? -17.398 3.761 32.562 1.00 34.35 ? 800 HOH B O 1 HETATM 8627 O O . HOH P 6 . ? 36.337 13.028 19.194 1.00 27.06 ? 801 HOH B O 1 HETATM 8628 O O . HOH P 6 . ? -17.243 11.960 12.259 1.00 32.71 ? 802 HOH B O 1 HETATM 8629 O O . HOH P 6 . ? 19.671 11.644 7.016 1.00 28.78 ? 803 HOH B O 1 HETATM 8630 O O . HOH P 6 . ? -8.549 1.124 5.151 1.00 32.87 ? 804 HOH B O 1 HETATM 8631 O O . HOH P 6 . ? 21.760 26.312 32.851 1.00 27.62 ? 805 HOH B O 1 HETATM 8632 O O . HOH P 6 . ? 1.654 21.546 14.930 1.00 28.82 ? 806 HOH B O 1 HETATM 8633 O O . HOH P 6 . ? 17.872 14.197 0.949 1.00 30.53 ? 807 HOH B O 1 HETATM 8634 O O . HOH P 6 . ? 19.078 4.327 -1.584 1.00 32.91 ? 808 HOH B O 1 HETATM 8635 O O . HOH P 6 . ? 30.729 -2.815 11.308 1.00 41.34 ? 809 HOH B O 1 HETATM 8636 O O . HOH P 6 . ? -25.141 3.281 11.566 1.00 29.75 ? 810 HOH B O 1 HETATM 8637 O O . HOH P 6 . ? -10.670 2.978 5.939 1.00 30.59 ? 811 HOH B O 1 HETATM 8638 O O . HOH P 6 . ? 14.782 -9.810 5.495 1.00 39.54 ? 812 HOH B O 1 HETATM 8639 O O . HOH P 6 . ? 13.856 25.344 7.448 1.00 38.20 ? 813 HOH B O 1 HETATM 8640 O O . HOH P 6 . ? -19.480 -4.622 20.583 1.00 39.60 ? 814 HOH B O 1 HETATM 8641 O O . HOH P 6 . ? -4.391 23.862 2.284 1.00 40.57 ? 815 HOH B O 1 HETATM 8642 O O . HOH P 6 . ? 18.696 8.630 -3.620 1.00 33.77 ? 816 HOH B O 1 HETATM 8643 O O . HOH P 6 . ? 37.138 8.032 18.329 1.00 42.25 ? 817 HOH B O 1 HETATM 8644 O O . HOH P 6 . ? 25.900 -5.467 21.806 1.00 36.22 ? 818 HOH B O 1 HETATM 8645 O O . HOH P 6 . ? 11.875 34.800 5.410 1.00 56.71 ? 819 HOH B O 1 HETATM 8646 O O . HOH P 6 . ? 11.493 2.766 35.183 1.00 38.27 ? 820 HOH B O 1 HETATM 8647 O O . HOH P 6 . ? 3.472 -10.977 19.639 1.00 44.68 ? 821 HOH B O 1 HETATM 8648 O O . HOH P 6 . ? 8.425 26.042 31.497 1.00 36.01 ? 822 HOH B O 1 HETATM 8649 O O . HOH P 6 . ? 9.099 10.642 -7.291 1.00 37.37 ? 823 HOH B O 1 HETATM 8650 O O . HOH P 6 . ? 30.402 10.131 18.677 1.00 35.47 ? 824 HOH B O 1 HETATM 8651 O O . HOH P 6 . ? 24.533 26.429 4.362 1.00 51.29 ? 825 HOH B O 1 HETATM 8652 O O . HOH P 6 . ? 14.455 6.431 -1.610 1.00 39.51 ? 826 HOH B O 1 HETATM 8653 O O . HOH P 6 . ? 1.753 15.226 -2.460 1.00 53.75 ? 827 HOH B O 1 HETATM 8654 O O . HOH P 6 . ? -1.245 -5.753 19.419 1.00 38.29 ? 828 HOH B O 1 HETATM 8655 O O . HOH P 6 . ? 3.368 31.787 21.961 1.00 48.71 ? 829 HOH B O 1 HETATM 8656 O O . HOH P 6 . ? -22.040 -12.865 10.085 1.00 37.89 ? 830 HOH B O 1 HETATM 8657 O O . HOH P 6 . ? 24.040 -3.692 4.555 1.00 31.96 ? 831 HOH B O 1 HETATM 8658 O O . HOH P 6 . ? 19.724 17.266 20.902 1.00 40.59 ? 832 HOH B O 1 HETATM 8659 O O . HOH P 6 . ? 10.953 16.976 25.350 1.00 33.88 ? 833 HOH B O 1 HETATM 8660 O O . HOH P 6 . ? 24.376 -16.282 21.004 1.00 59.08 ? 834 HOH B O 1 HETATM 8661 O O . HOH P 6 . ? 25.700 14.382 21.729 1.00 37.28 ? 835 HOH B O 1 HETATM 8662 O O . HOH P 6 . ? -18.979 -5.525 18.083 1.00 44.27 ? 836 HOH B O 1 HETATM 8663 O O . HOH P 6 . ? -10.268 -21.780 5.782 1.00 41.71 ? 837 HOH B O 1 HETATM 8664 O O . HOH P 6 . ? -27.176 12.789 21.231 1.00 40.83 ? 838 HOH B O 1 HETATM 8665 O O . HOH P 6 . ? 17.019 31.157 4.499 1.00 56.45 ? 839 HOH B O 1 HETATM 8666 O O . HOH P 6 . ? 8.114 23.928 1.886 1.00 50.13 ? 840 HOH B O 1 HETATM 8667 O O . HOH P 6 . ? 14.558 -2.811 26.717 1.00 31.23 ? 841 HOH B O 1 HETATM 8668 O O . HOH P 6 . ? 23.780 -8.373 12.723 1.00 42.77 ? 842 HOH B O 1 HETATM 8669 O O . HOH P 6 . ? 5.919 28.782 32.666 1.00 40.85 ? 843 HOH B O 1 HETATM 8670 O O . HOH P 6 . ? -16.742 -6.843 13.276 1.00 41.00 ? 844 HOH B O 1 HETATM 8671 O O . HOH P 6 . ? -27.523 12.036 17.070 1.00 36.35 ? 845 HOH B O 1 HETATM 8672 O O . HOH P 6 . ? 24.241 -5.432 31.041 1.00 41.39 ? 846 HOH B O 1 HETATM 8673 O O . HOH P 6 . ? -3.213 19.760 -3.340 1.00 33.76 ? 847 HOH B O 1 HETATM 8674 O O . HOH P 6 . ? 10.390 -17.895 13.799 1.00 38.63 ? 848 HOH B O 1 HETATM 8675 O O . HOH P 6 . ? 2.354 34.229 14.577 1.00 55.30 ? 849 HOH B O 1 HETATM 8676 O O . HOH P 6 . ? 5.217 14.515 -5.907 1.00 38.79 ? 851 HOH B O 1 HETATM 8677 O O . HOH P 6 . ? 28.140 17.211 23.877 1.00 40.13 ? 852 HOH B O 1 HETATM 8678 O O . HOH P 6 . ? -24.607 5.821 8.284 1.00 33.42 ? 853 HOH B O 1 HETATM 8679 O O . HOH P 6 . ? -11.609 -4.955 27.630 1.00 32.52 ? 854 HOH B O 1 HETATM 8680 O O . HOH P 6 . ? -14.182 12.264 28.155 1.00 32.94 ? 855 HOH B O 1 HETATM 8681 O O . HOH P 6 . ? 13.040 18.414 39.623 1.00 37.79 ? 856 HOH B O 1 HETATM 8682 O O . HOH P 6 . ? 18.437 17.380 18.681 1.00 32.16 ? 857 HOH B O 1 HETATM 8683 O O . HOH P 6 . ? -18.116 22.602 9.225 1.00 49.37 ? 858 HOH B O 1 HETATM 8684 O O . HOH P 6 . ? 28.806 7.951 29.477 1.00 38.59 ? 859 HOH B O 1 HETATM 8685 O O . HOH P 6 . ? 12.376 0.986 17.475 1.00 50.79 ? 860 HOH B O 1 HETATM 8686 O O . HOH P 6 . ? -7.551 -9.228 21.003 1.00 32.29 ? 861 HOH B O 1 HETATM 8687 O O . HOH P 6 . ? -7.586 15.533 25.744 1.00 34.57 ? 862 HOH B O 1 HETATM 8688 O O . HOH P 6 . ? -9.894 -2.780 31.355 1.00 57.68 ? 863 HOH B O 1 HETATM 8689 O O . HOH P 6 . ? -9.655 12.037 -4.147 1.00 37.32 ? 864 HOH B O 1 HETATM 8690 O O . HOH P 6 . ? 7.072 21.605 40.241 1.00 53.91 ? 865 HOH B O 1 HETATM 8691 O O . HOH P 6 . ? -2.151 21.873 7.312 1.00 30.43 ? 866 HOH B O 1 HETATM 8692 O O . HOH P 6 . ? 11.553 14.727 -9.176 1.00 38.17 ? 867 HOH B O 1 HETATM 8693 O O . HOH P 6 . ? 22.001 -7.008 4.229 1.00 37.88 ? 868 HOH B O 1 HETATM 8694 O O . HOH P 6 . ? 21.514 0.125 3.235 1.00 33.70 ? 869 HOH B O 1 HETATM 8695 O O . HOH P 6 . ? -12.068 18.173 18.797 1.00 40.69 ? 870 HOH B O 1 HETATM 8696 O O . HOH P 6 . ? -1.702 -11.222 6.825 1.00 39.20 ? 871 HOH B O 1 HETATM 8697 O O . HOH P 6 . ? -1.061 19.868 8.582 1.00 35.57 ? 872 HOH B O 1 HETATM 8698 O O . HOH P 6 . ? 25.757 13.991 17.472 1.00 51.29 ? 873 HOH B O 1 HETATM 8699 O O . HOH P 6 . ? -11.665 11.848 28.684 1.00 33.27 ? 874 HOH B O 1 HETATM 8700 O O . HOH P 6 . ? 21.870 25.638 13.825 1.00 34.40 ? 875 HOH B O 1 HETATM 8701 O O . HOH P 6 . ? 26.014 27.673 20.403 1.00 45.95 ? 876 HOH B O 1 HETATM 8702 O O . HOH P 6 . ? 8.812 31.538 4.807 1.00 38.91 ? 877 HOH B O 1 HETATM 8703 O O . HOH P 6 . ? 18.323 13.268 -5.722 1.00 39.98 ? 878 HOH B O 1 HETATM 8704 O O . HOH P 6 . ? 24.245 2.194 38.070 1.00 41.72 ? 879 HOH B O 1 HETATM 8705 O O . HOH P 6 . ? 14.828 22.012 36.200 1.00 45.30 ? 880 HOH B O 1 HETATM 8706 O O . HOH P 6 . ? 8.558 -7.259 23.976 1.00 36.37 ? 881 HOH B O 1 HETATM 8707 O O . HOH P 6 . ? 10.397 -5.300 36.150 1.00 41.77 ? 882 HOH B O 1 HETATM 8708 O O . HOH P 6 . ? 28.931 36.196 28.768 1.00 48.09 ? 883 HOH B O 1 HETATM 8709 O O . HOH P 6 . ? 18.442 -6.522 24.894 1.00 40.09 ? 884 HOH B O 1 HETATM 8710 O O . HOH P 6 . ? -13.439 17.598 16.283 1.00 36.35 ? 885 HOH B O 1 HETATM 8711 O O . HOH P 6 . ? 20.963 9.113 6.035 1.00 33.30 ? 886 HOH B O 1 HETATM 8712 O O . HOH P 6 . ? -1.225 20.666 29.660 1.00 40.37 ? 887 HOH B O 1 HETATM 8713 O O . HOH P 6 . ? 6.466 -17.549 8.237 1.00 36.82 ? 888 HOH B O 1 HETATM 8714 O O . HOH P 6 . ? 16.466 35.163 26.665 1.00 38.28 ? 889 HOH B O 1 HETATM 8715 O O . HOH P 6 . ? 16.512 39.881 19.874 1.00 41.77 ? 890 HOH B O 1 HETATM 8716 O O . HOH P 6 . ? 15.559 11.855 12.158 1.00 31.35 ? 891 HOH B O 1 HETATM 8717 O O . HOH P 6 . ? 14.969 -10.522 18.425 1.00 32.68 ? 892 HOH B O 1 HETATM 8718 O O . HOH P 6 . ? 20.564 -7.929 23.911 1.00 38.98 ? 893 HOH B O 1 HETATM 8719 O O . HOH P 6 . ? 13.094 17.221 23.854 1.00 41.12 ? 894 HOH B O 1 HETATM 8720 O O . HOH P 6 . ? 8.384 14.454 40.896 1.00 46.18 ? 895 HOH B O 1 HETATM 8721 O O . HOH P 6 . ? 35.893 4.191 17.902 1.00 39.91 ? 896 HOH B O 1 HETATM 8722 O O . HOH P 6 . ? -19.856 11.517 12.608 1.00 33.46 ? 897 HOH B O 1 HETATM 8723 O O . HOH P 6 . ? -7.581 1.887 38.535 1.00 34.26 ? 898 HOH B O 1 HETATM 8724 O O . HOH P 6 . ? -6.652 19.913 17.841 1.00 38.33 ? 899 HOH B O 1 HETATM 8725 O O . HOH P 6 . ? -25.030 -18.654 9.422 1.00 47.54 ? 900 HOH B O 1 HETATM 8726 O O . HOH P 6 . ? 23.144 -10.207 18.489 1.00 38.32 ? 901 HOH B O 1 HETATM 8727 O O . HOH P 6 . ? 23.607 28.695 16.729 1.00 45.47 ? 902 HOH B O 1 HETATM 8728 O O . HOH P 6 . ? 25.929 -0.104 30.509 1.00 34.75 ? 903 HOH B O 1 HETATM 8729 O O . HOH P 6 . ? -4.845 18.678 18.926 1.00 40.59 ? 904 HOH B O 1 HETATM 8730 O O . HOH P 6 . ? 31.394 10.266 10.488 1.00 39.97 ? 905 HOH B O 1 HETATM 8731 O O . HOH P 6 . ? 20.223 13.598 -7.844 1.00 45.58 ? 906 HOH B O 1 HETATM 8732 O O . HOH P 6 . ? 21.365 3.125 2.228 1.00 34.39 ? 907 HOH B O 1 HETATM 8733 O O . HOH P 6 . ? 3.758 -10.955 5.867 1.00 54.03 ? 908 HOH B O 1 HETATM 8734 O O . HOH P 6 . ? 20.856 32.573 30.477 1.00 35.69 ? 909 HOH B O 1 HETATM 8735 O O . HOH P 6 . ? 26.570 27.721 3.399 1.00 56.64 ? 910 HOH B O 1 HETATM 8736 O O . HOH P 6 . ? 1.457 23.450 33.674 1.00 39.74 ? 911 HOH B O 1 HETATM 8737 O O . HOH P 6 . ? 14.425 27.591 31.868 1.00 39.68 ? 912 HOH B O 1 HETATM 8738 O O . HOH P 6 . ? 21.941 20.217 36.216 1.00 47.38 ? 913 HOH B O 1 HETATM 8739 O O . HOH P 6 . ? -23.552 -18.933 11.930 1.00 40.42 ? 914 HOH B O 1 HETATM 8740 O O . HOH P 6 . ? -2.547 21.163 15.406 1.00 46.51 ? 915 HOH B O 1 HETATM 8741 O O . HOH P 6 . ? -17.481 -19.832 13.481 1.00 48.18 ? 916 HOH B O 1 HETATM 8742 O O . HOH P 6 . ? -26.330 -2.849 23.996 1.00 56.69 ? 917 HOH B O 1 HETATM 8743 O O . HOH P 6 . ? -9.785 -19.260 6.933 1.00 27.70 ? 918 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLY 1 1 ? ? ? A . n A 1 2 GLY 2 2 ? ? ? A . n A 1 3 SER 3 3 3 SER SER A . n A 1 4 ILE 4 4 4 ILE ILE A . n A 1 5 ASP 5 5 5 ASP ASP A . n A 1 6 GLU 6 6 6 GLU GLU A . n A 1 7 THR 7 7 7 THR THR A . n A 1 8 ARG 8 8 8 ARG ARG A . n A 1 9 ALA 9 9 9 ALA ALA A . n A 1 10 HIS 10 10 10 HIS HIS A . n A 1 11 LEU 11 11 11 LEU LEU A . n A 1 12 LEU 12 12 12 LEU LEU A . n A 1 13 LEU 13 13 13 LEU LEU A . n A 1 14 LYS 14 14 14 LYS LYS A . n A 1 15 GLU 15 15 15 GLU GLU A . n A 1 16 LYS 16 16 16 LYS LYS A . n A 1 17 MET 17 17 17 MET MET A . n A 1 18 MET 18 18 18 MET MET A . n A 1 19 ARG 19 19 19 ARG ARG A . n A 1 20 LEU 20 20 20 LEU LEU A . n A 1 21 GLY 21 21 21 GLY GLY A . n A 1 22 GLY 22 22 22 GLY GLY A . n A 1 23 ARG 23 23 23 ARG ARG A . n A 1 24 LEU 24 24 24 LEU LEU A . n A 1 25 VAL 25 25 25 VAL VAL A . n A 1 26 LEU 26 26 26 LEU LEU A . n A 1 27 ASN 27 27 27 ASN ASN A . n A 1 28 THR 28 28 28 THR THR A . n A 1 29 LYS 29 29 29 LYS LYS A . n A 1 30 GLU 30 30 30 GLU GLU A . n A 1 31 GLU 31 31 31 GLU GLU A . n A 1 32 LEU 32 32 32 LEU LEU A . n A 1 33 ALA 33 33 33 ALA ALA A . n A 1 34 ASN 34 34 34 ASN ASN A . n A 1 35 GLU 35 35 35 GLU GLU A . n A 1 36 ARG 36 36 36 ARG ARG A . n A 1 37 LEU 37 37 37 LEU LEU A . n A 1 38 MET 38 38 38 MET MET A . n A 1 39 THR 39 39 39 THR THR A . n A 1 40 LEU 40 40 40 LEU LEU A . n A 1 41 LYS 41 41 41 LYS LYS A . n A 1 42 ILE 42 42 42 ILE ILE A . n A 1 43 ALA 43 43 43 ALA ALA A . n A 1 44 GLU 44 44 44 GLU GLU A . n A 1 45 MET 45 45 45 MET MET A . n A 1 46 LYS 46 46 46 LYS LYS A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 ALA 48 48 48 ALA ALA A . n A 1 49 MET 49 49 49 MET MET A . n A 1 50 ARG 50 50 50 ARG ARG A . n A 1 51 THR 51 51 51 THR THR A . n A 1 52 LEU 52 52 52 LEU LEU A . n A 1 53 ILE 53 53 53 ILE ILE A . n A 1 54 PHE 54 54 54 PHE PHE A . n A 1 55 PRO 55 55 55 PRO PRO A . n A 1 56 PRO 56 56 56 PRO PRO A . n A 1 57 SER 57 57 57 SER SER A . n A 1 58 MET 58 58 58 MET MET A . n A 1 59 HIS 59 59 59 HIS HIS A . n A 1 60 PHE 60 60 60 PHE PHE A . n A 1 61 PHE 61 61 61 PHE PHE A . n A 1 62 GLN 62 62 62 GLN GLN A . n A 1 63 ALA 63 63 63 ALA ALA A . n A 1 64 LYS 64 64 64 LYS LYS A . n A 1 65 HIS 65 65 65 HIS HIS A . n A 1 66 LEU 66 66 66 LEU LEU A . n A 1 67 ILE 67 67 67 ILE ILE A . n A 1 68 GLU 68 68 68 GLU GLU A . n A 1 69 ARG 69 69 69 ARG ARG A . n A 1 70 SER 70 70 70 SER SER A . n A 1 71 GLN 71 71 71 GLN GLN A . n A 1 72 VAL 72 72 72 VAL VAL A . n A 1 73 PHE 73 73 73 PHE PHE A . n A 1 74 ASN 74 74 74 ASN ASN A . n A 1 75 ILE 75 75 75 ILE ILE A . n A 1 76 LEU 76 76 76 LEU LEU A . n A 1 77 ARG 77 77 77 ARG ARG A . n A 1 78 MET 78 78 78 MET MET A . n A 1 79 MET 79 79 79 MET MET A . n A 1 80 PRO 80 80 80 PRO PRO A . n A 1 81 LYS 81 81 81 LYS LYS A . n A 1 82 GLY 82 82 82 GLY GLY A . n A 1 83 ALA 83 83 83 ALA ALA A . n A 1 84 ALA 84 84 84 ALA ALA A . n A 1 85 LEU 85 85 85 LEU LEU A . n A 1 86 HIS 86 86 86 HIS HIS A . n A 1 87 LEU 87 87 87 LEU LEU A . n A 1 88 HIS 88 88 88 HIS HIS A . n A 1 89 ASP 89 89 89 ASP ASP A . n A 1 90 ILE 90 90 90 ILE ILE A . n A 1 91 GLY 91 91 91 GLY GLY A . n A 1 92 ILE 92 92 92 ILE ILE A . n A 1 93 VAL 93 93 93 VAL VAL A . n A 1 94 THR 94 94 94 THR THR A . n A 1 95 MET 95 95 95 MET MET A . n A 1 96 ASP 96 96 96 ASP ASP A . n A 1 97 TRP 97 97 97 TRP TRP A . n A 1 98 LEU 98 98 98 LEU LEU A . n A 1 99 VAL 99 99 99 VAL VAL A . n A 1 100 ARG 100 100 100 ARG ARG A . n A 1 101 ASN 101 101 101 ASN ASN A . n A 1 102 VAL 102 102 102 VAL VAL A . n A 1 103 THR 103 103 103 THR THR A . n A 1 104 TYR 104 104 104 TYR TYR A . n A 1 105 ARG 105 105 105 ARG ARG A . n A 1 106 PRO 106 106 106 PRO PRO A . n A 1 107 HIS 107 107 107 HIS HIS A . n A 1 108 CYS 108 108 108 CYS CYS A . n A 1 109 HIS 109 109 109 HIS HIS A . n A 1 110 ILE 110 110 110 ILE ILE A . n A 1 111 CYS 111 111 111 CYS CYS A . n A 1 112 PHE 112 112 112 PHE PHE A . n A 1 113 THR 113 113 113 THR THR A . n A 1 114 PRO 114 114 114 PRO PRO A . n A 1 115 ARG 115 115 115 ARG ARG A . n A 1 116 GLY 116 116 116 GLY GLY A . n A 1 117 ILE 117 117 117 ILE ILE A . n A 1 118 MET 118 118 118 MET MET A . n A 1 119 GLN 119 119 119 GLN GLN A . n A 1 120 PHE 120 120 120 PHE PHE A . n A 1 121 ARG 121 121 121 ARG ARG A . n A 1 122 PHE 122 122 122 PHE PHE A . n A 1 123 ALA 123 123 123 ALA ALA A . n A 1 124 HIS 124 124 124 HIS HIS A . n A 1 125 PRO 125 125 125 PRO PRO A . n A 1 126 THR 126 126 126 THR THR A . n A 1 127 PRO 127 127 127 PRO PRO A . n A 1 128 ARG 128 128 128 ARG ARG A . n A 1 129 PRO 129 129 129 PRO PRO A . n A 1 130 SER 130 130 130 SER SER A . n A 1 131 GLU 131 131 131 GLU GLU A . n A 1 132 LYS 132 132 132 LYS LYS A . n A 1 133 CYS 133 133 133 CYS CYS A . n A 1 134 SER 134 134 134 SER SER A . n A 1 135 LYS 135 135 135 LYS LYS A . n A 1 136 TRP 136 136 136 TRP TRP A . n A 1 137 ILE 137 137 137 ILE ILE A . n A 1 138 LEU 138 138 138 LEU LEU A . n A 1 139 LEU 139 139 139 LEU LEU A . n A 1 140 GLU 140 140 140 GLU GLU A . n A 1 141 ASP 141 141 141 ASP ASP A . n A 1 142 TYR 142 142 142 TYR TYR A . n A 1 143 ARG 143 143 143 ARG ARG A . n A 1 144 LYS 144 144 144 LYS LYS A . n A 1 145 ARG 145 145 145 ARG ARG A . n A 1 146 VAL 146 146 146 VAL VAL A . n A 1 147 GLN 147 147 147 GLN GLN A . n A 1 148 ASN 148 148 148 ASN ASN A . n A 1 149 VAL 149 149 149 VAL VAL A . n A 1 150 THR 150 150 150 THR THR A . n A 1 151 GLU 151 151 151 GLU GLU A . n A 1 152 PHE 152 152 152 PHE PHE A . n A 1 153 ASP 153 153 153 ASP ASP A . n A 1 154 ASP 154 154 154 ASP ASP A . n A 1 155 SER 155 155 155 SER SER A . n A 1 156 LEU 156 156 156 LEU LEU A . n A 1 157 LEU 157 157 157 LEU LEU A . n A 1 158 ARG 158 158 158 ARG ARG A . n A 1 159 ASN 159 159 159 ASN ASN A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 THR 161 161 161 THR THR A . n A 1 162 LEU 162 162 162 LEU LEU A . n A 1 163 VAL 163 163 163 VAL VAL A . n A 1 164 THR 164 164 164 THR THR A . n A 1 165 GLN 165 165 165 GLN GLN A . n A 1 166 HIS 166 166 166 HIS HIS A . n A 1 167 PRO 167 167 167 PRO PRO A . n A 1 168 GLU 168 168 168 GLU GLU A . n A 1 169 VAL 169 169 169 VAL VAL A . n A 1 170 ILE 170 170 170 ILE ILE A . n A 1 171 TYR 171 171 171 TYR TYR A . n A 1 172 THR 172 172 172 THR THR A . n A 1 173 ASN 173 173 173 ASN ASN A . n A 1 174 GLN 174 174 174 GLN GLN A . n A 1 175 ASN 175 175 175 ASN ASN A . n A 1 176 VAL 176 176 176 VAL VAL A . n A 1 177 VAL 177 177 177 VAL VAL A . n A 1 178 TRP 178 178 178 TRP TRP A . n A 1 179 SER 179 179 179 SER SER A . n A 1 180 LYS 180 180 180 LYS LYS A . n A 1 181 PHE 181 181 181 PHE PHE A . n A 1 182 GLU 182 182 182 GLU GLU A . n A 1 183 THR 183 183 183 THR THR A . n A 1 184 ILE 184 184 184 ILE ILE A . n A 1 185 PHE 185 185 185 PHE PHE A . n A 1 186 PHE 186 186 186 PHE PHE A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 ILE 188 188 188 ILE ILE A . n A 1 189 SER 189 189 189 SER SER A . n A 1 190 GLY 190 190 190 GLY GLY A . n A 1 191 LEU 191 191 191 LEU LEU A . n A 1 192 ILE 192 192 192 ILE ILE A . n A 1 193 HIS 193 193 193 HIS HIS A . n A 1 194 TYR 194 194 194 TYR TYR A . n A 1 195 ALA 195 195 195 ALA ALA A . n A 1 196 PRO 196 196 196 PRO PRO A . n A 1 197 VAL 197 197 197 VAL VAL A . n A 1 198 PHE 198 198 198 PHE PHE A . n A 1 199 ARG 199 199 199 ARG ARG A . n A 1 200 ASP 200 200 200 ASP ASP A . n A 1 201 TYR 201 201 201 TYR TYR A . n A 1 202 VAL 202 202 202 VAL VAL A . n A 1 203 PHE 203 203 203 PHE PHE A . n A 1 204 ARG 204 204 204 ARG ARG A . n A 1 205 SER 205 205 205 SER SER A . n A 1 206 MET 206 206 206 MET MET A . n A 1 207 GLN 207 207 207 GLN GLN A . n A 1 208 GLU 208 208 208 GLU GLU A . n A 1 209 PHE 209 209 209 PHE PHE A . n A 1 210 TYR 210 210 210 TYR TYR A . n A 1 211 GLU 211 211 211 GLU GLU A . n A 1 212 ASP 212 212 212 ASP ASP A . n A 1 213 ASN 213 213 213 ASN ASN A . n A 1 214 VAL 214 214 214 VAL VAL A . n A 1 215 LEU 215 215 215 LEU LEU A . n A 1 216 TYR 216 216 216 TYR TYR A . n A 1 217 MET 217 217 217 MET MET A . n A 1 218 GLU 218 218 218 GLU GLU A . n A 1 219 ILE 219 219 219 ILE ILE A . n A 1 220 ARG 220 220 220 ARG ARG A . n A 1 221 ALA 221 221 221 ALA ALA A . n A 1 222 ARG 222 222 222 ARG ARG A . n A 1 223 LEU 223 223 223 LEU LEU A . n A 1 224 LEU 224 224 224 LEU LEU A . n A 1 225 PRO 225 225 225 PRO PRO A . n A 1 226 VAL 226 226 226 VAL VAL A . n A 1 227 TYR 227 227 227 TYR TYR A . n A 1 228 GLU 228 228 228 GLU GLU A . n A 1 229 LEU 229 229 229 LEU LEU A . n A 1 230 SER 230 230 230 SER SER A . n A 1 231 GLY 231 231 231 GLY GLY A . n A 1 232 GLU 232 232 232 GLU GLU A . n A 1 233 HIS 233 233 233 HIS HIS A . n A 1 234 HIS 234 234 234 HIS HIS A . n A 1 235 ASP 235 235 235 ASP ASP A . n A 1 236 GLU 236 236 236 GLU GLU A . n A 1 237 GLU 237 237 237 GLU GLU A . n A 1 238 TRP 238 238 238 TRP TRP A . n A 1 239 SER 239 239 239 SER SER A . n A 1 240 VAL 240 240 240 VAL VAL A . n A 1 241 LYS 241 241 241 LYS LYS A . n A 1 242 THR 242 242 242 THR THR A . n A 1 243 TYR 243 243 243 TYR TYR A . n A 1 244 GLN 244 244 244 GLN GLN A . n A 1 245 GLU 245 245 245 GLU GLU A . n A 1 246 VAL 246 246 246 VAL VAL A . n A 1 247 ALA 247 247 247 ALA ALA A . n A 1 248 GLN 248 248 248 GLN GLN A . n A 1 249 LYS 249 249 249 LYS LYS A . n A 1 250 PHE 250 250 250 PHE PHE A . n A 1 251 VAL 251 251 251 VAL VAL A . n A 1 252 GLU 252 252 252 GLU GLU A . n A 1 253 THR 253 253 253 THR THR A . n A 1 254 HIS 254 254 254 HIS HIS A . n A 1 255 PRO 255 255 255 PRO PRO A . n A 1 256 GLU 256 256 256 GLU GLU A . n A 1 257 PHE 257 257 257 PHE PHE A . n A 1 258 ILE 258 258 258 ILE ILE A . n A 1 259 GLY 259 259 259 GLY GLY A . n A 1 260 ILE 260 260 260 ILE ILE A . n A 1 261 LYS 261 261 261 LYS LYS A . n A 1 262 ILE 262 262 262 ILE ILE A . n A 1 263 ILE 263 263 263 ILE ILE A . n A 1 264 TYR 264 264 264 TYR TYR A . n A 1 265 SER 265 265 265 SER SER A . n A 1 266 ASP 266 266 266 ASP ASP A . n A 1 267 HIS 267 267 267 HIS HIS A . n A 1 268 ARG 268 268 268 ARG ARG A . n A 1 269 SER 269 269 269 SER SER A . n A 1 270 LYS 270 270 270 LYS LYS A . n A 1 271 ASP 271 271 271 ASP ASP A . n A 1 272 VAL 272 272 272 VAL VAL A . n A 1 273 ALA 273 273 273 ALA ALA A . n A 1 274 VAL 274 274 274 VAL VAL A . n A 1 275 ILE 275 275 275 ILE ILE A . n A 1 276 ALA 276 276 276 ALA ALA A . n A 1 277 GLU 277 277 277 GLU GLU A . n A 1 278 SER 278 278 278 SER SER A . n A 1 279 ILE 279 279 279 ILE ILE A . n A 1 280 ARG 280 280 280 ARG ARG A . n A 1 281 MET 281 281 281 MET MET A . n A 1 282 ALA 282 282 282 ALA ALA A . n A 1 283 MET 283 283 283 MET MET A . n A 1 284 GLY 284 284 284 GLY GLY A . n A 1 285 LEU 285 285 285 LEU LEU A . n A 1 286 ARG 286 286 286 ARG ARG A . n A 1 287 ILE 287 287 287 ILE ILE A . n A 1 288 LYS 288 288 288 LYS LYS A . n A 1 289 PHE 289 289 289 PHE PHE A . n A 1 290 PRO 290 290 290 PRO PRO A . n A 1 291 THR 291 291 291 THR THR A . n A 1 292 VAL 292 292 292 VAL VAL A . n A 1 293 VAL 293 293 293 VAL VAL A . n A 1 294 ALA 294 294 294 ALA ALA A . n A 1 295 GLY 295 295 295 GLY GLY A . n A 1 296 PHE 296 296 296 PHE PHE A . n A 1 297 ASP 297 297 297 ASP ASP A . n A 1 298 LEU 298 298 298 LEU LEU A . n A 1 299 VAL 299 299 299 VAL VAL A . n A 1 300 GLY 300 300 300 GLY GLY A . n A 1 301 HIS 301 301 301 HIS HIS A . n A 1 302 GLU 302 302 302 GLU GLU A . n A 1 303 ASP 303 303 303 ASP ASP A . n A 1 304 THR 304 304 304 THR THR A . n A 1 305 GLY 305 305 305 GLY GLY A . n A 1 306 HIS 306 306 306 HIS HIS A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 LEU 308 308 308 LEU LEU A . n A 1 309 HIS 309 309 309 HIS HIS A . n A 1 310 ASP 310 310 310 ASP ASP A . n A 1 311 TYR 311 311 311 TYR TYR A . n A 1 312 LYS 312 312 312 LYS LYS A . n A 1 313 GLU 313 313 313 GLU GLU A . n A 1 314 ALA 314 314 314 ALA ALA A . n A 1 315 LEU 315 315 315 LEU LEU A . n A 1 316 MET 316 316 316 MET MET A . n A 1 317 ILE 317 317 317 ILE ILE A . n A 1 318 PRO 318 318 318 PRO PRO A . n A 1 319 ALA 319 319 319 ALA ALA A . n A 1 320 LYS 320 320 320 LYS LYS A . n A 1 321 ASP 321 321 321 ASP ASP A . n A 1 322 GLY 322 322 322 GLY GLY A . n A 1 323 VAL 323 323 323 VAL VAL A . n A 1 324 LYS 324 324 324 LYS LYS A . n A 1 325 LEU 325 325 325 LEU LEU A . n A 1 326 PRO 326 326 326 PRO PRO A . n A 1 327 TYR 327 327 327 TYR TYR A . n A 1 328 PHE 328 328 328 PHE PHE A . n A 1 329 PHE 329 329 329 PHE PHE A . n A 1 330 HIS 330 330 330 HIS HIS A . n A 1 331 ALA 331 331 331 ALA ALA A . n A 1 332 GLY 332 332 332 GLY GLY A . n A 1 333 GLU 333 333 333 GLU GLU A . n A 1 334 THR 334 334 334 THR THR A . n A 1 335 ASP 335 335 335 ASP ASP A . n A 1 336 TRP 336 336 336 TRP TRP A . n A 1 337 GLN 337 337 337 GLN GLN A . n A 1 338 GLY 338 338 338 GLY GLY A . n A 1 339 THR 339 339 339 THR THR A . n A 1 340 SER 340 340 340 SER SER A . n A 1 341 ILE 341 341 341 ILE ILE A . n A 1 342 ASP 342 342 342 ASP ASP A . n A 1 343 ARG 343 343 343 ARG ARG A . n A 1 344 ASN 344 344 344 ASN ASN A . n A 1 345 ILE 345 345 345 ILE ILE A . n A 1 346 LEU 346 346 346 LEU LEU A . n A 1 347 ASP 347 347 347 ASP ASP A . n A 1 348 ALA 348 348 348 ALA ALA A . n A 1 349 LEU 349 349 349 LEU LEU A . n A 1 350 MET 350 350 350 MET MET A . n A 1 351 LEU 351 351 351 LEU LEU A . n A 1 352 ASN 352 352 352 ASN ASN A . n A 1 353 THR 353 353 353 THR THR A . n A 1 354 THR 354 354 354 THR THR A . n A 1 355 ARG 355 355 355 ARG ARG A . n A 1 356 ILE 356 356 356 ILE ILE A . n A 1 357 GLY 357 357 357 GLY GLY A . n A 1 358 HIS 358 358 358 HIS HIS A . n A 1 359 GLY 359 359 359 GLY GLY A . n A 1 360 PHE 360 360 360 PHE PHE A . n A 1 361 ALA 361 361 361 ALA ALA A . n A 1 362 LEU 362 362 362 LEU LEU A . n A 1 363 SER 363 363 363 SER SER A . n A 1 364 LYS 364 364 364 LYS LYS A . n A 1 365 HIS 365 365 365 HIS HIS A . n A 1 366 PRO 366 366 366 PRO PRO A . n A 1 367 ALA 367 367 367 ALA ALA A . n A 1 368 VAL 368 368 368 VAL VAL A . n A 1 369 ARG 369 369 369 ARG ARG A . n A 1 370 THR 370 370 370 THR THR A . n A 1 371 TYR 371 371 371 TYR TYR A . n A 1 372 SER 372 372 372 SER SER A . n A 1 373 TRP 373 373 373 TRP TRP A . n A 1 374 LYS 374 374 374 LYS LYS A . n A 1 375 LYS 375 375 375 LYS LYS A . n A 1 376 ASP 376 376 376 ASP ASP A . n A 1 377 ILE 377 377 377 ILE ILE A . n A 1 378 PRO 378 378 378 PRO PRO A . n A 1 379 ILE 379 379 379 ILE ILE A . n A 1 380 GLU 380 380 380 GLU GLU A . n A 1 381 VAL 381 381 381 VAL VAL A . n A 1 382 CYS 382 382 382 CYS CYS A . n A 1 383 PRO 383 383 383 PRO PRO A . n A 1 384 ILE 384 384 384 ILE ILE A . n A 1 385 SER 385 385 385 SER SER A . n A 1 386 ASN 386 386 386 ASN ASN A . n A 1 387 GLN 387 387 387 GLN GLN A . n A 1 388 VAL 388 388 388 VAL VAL A . n A 1 389 LEU 389 389 389 LEU LEU A . n A 1 390 LYS 390 390 390 LYS LYS A . n A 1 391 LEU 391 391 391 LEU LEU A . n A 1 392 VAL 392 392 392 VAL VAL A . n A 1 393 SER 393 393 393 SER SER A . n A 1 394 ASP 394 394 394 ASP ASP A . n A 1 395 LEU 395 395 395 LEU LEU A . n A 1 396 ARG 396 396 396 ARG ARG A . n A 1 397 ASN 397 397 397 ASN ASN A . n A 1 398 HIS 398 398 398 HIS HIS A . n A 1 399 PRO 399 399 399 PRO PRO A . n A 1 400 VAL 400 400 400 VAL VAL A . n A 1 401 ALA 401 401 401 ALA ALA A . n A 1 402 THR 402 402 402 THR THR A . n A 1 403 LEU 403 403 403 LEU LEU A . n A 1 404 MET 404 404 404 MET MET A . n A 1 405 ALA 405 405 405 ALA ALA A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 GLY 407 407 407 GLY GLY A . n A 1 408 HIS 408 408 408 HIS HIS A . n A 1 409 PRO 409 409 409 PRO PRO A . n A 1 410 MET 410 410 410 MET MET A . n A 1 411 VAL 411 411 411 VAL VAL A . n A 1 412 ILE 412 412 412 ILE ILE A . n A 1 413 SER 413 413 413 SER SER A . n A 1 414 SER 414 414 414 SER SER A . n A 1 415 ASP 415 415 415 ASP ASP A . n A 1 416 ASP 416 416 416 ASP ASP A . n A 1 417 PRO 417 417 417 PRO PRO A . n A 1 418 ALA 418 418 418 ALA ALA A . n A 1 419 MET 419 419 419 MET MET A . n A 1 420 PHE 420 420 420 PHE PHE A . n A 1 421 GLY 421 421 421 GLY GLY A . n A 1 422 ALA 422 422 422 ALA ALA A . n A 1 423 LYS 423 423 423 LYS LYS A . n A 1 424 GLY 424 424 424 GLY GLY A . n A 1 425 LEU 425 425 425 LEU LEU A . n A 1 426 SER 426 426 426 SER SER A . n A 1 427 TYR 427 427 427 TYR TYR A . n A 1 428 ASP 428 428 428 ASP ASP A . n A 1 429 PHE 429 429 429 PHE PHE A . n A 1 430 TYR 430 430 430 TYR TYR A . n A 1 431 GLU 431 431 431 GLU GLU A . n A 1 432 VAL 432 432 432 VAL VAL A . n A 1 433 PHE 433 433 433 PHE PHE A . n A 1 434 MET 434 434 434 MET MET A . n A 1 435 GLY 435 435 435 GLY GLY A . n A 1 436 ILE 436 436 436 ILE ILE A . n A 1 437 GLY 437 437 437 GLY GLY A . n A 1 438 GLY 438 438 438 GLY GLY A . n A 1 439 MET 439 439 439 MET MET A . n A 1 440 LYS 440 440 440 LYS LYS A . n A 1 441 ALA 441 441 441 ALA ALA A . n A 1 442 ASP 442 442 442 ASP ASP A . n A 1 443 LEU 443 443 443 LEU LEU A . n A 1 444 ARG 444 444 444 ARG ARG A . n A 1 445 THR 445 445 445 THR THR A . n A 1 446 LEU 446 446 446 LEU LEU A . n A 1 447 LYS 447 447 447 LYS LYS A . n A 1 448 GLN 448 448 448 GLN GLN A . n A 1 449 LEU 449 449 449 LEU LEU A . n A 1 450 ALA 450 450 450 ALA ALA A . n A 1 451 MET 451 451 451 MET MET A . n A 1 452 ASN 452 452 452 ASN ASN A . n A 1 453 SER 453 453 453 SER SER A . n A 1 454 ILE 454 454 454 ILE ILE A . n A 1 455 LYS 455 455 455 LYS LYS A . n A 1 456 TYR 456 456 456 TYR TYR A . n A 1 457 SER 457 457 457 SER SER A . n A 1 458 THR 458 458 458 THR THR A . n A 1 459 LEU 459 459 459 LEU LEU A . n A 1 460 LEU 460 460 460 LEU LEU A . n A 1 461 GLU 461 461 461 GLU GLU A . n A 1 462 SER 462 462 462 SER SER A . n A 1 463 GLU 463 463 463 GLU GLU A . n A 1 464 LYS 464 464 464 LYS LYS A . n A 1 465 ASN 465 465 465 ASN ASN A . n A 1 466 THR 466 466 466 THR THR A . n A 1 467 PHE 467 467 467 PHE PHE A . n A 1 468 MET 468 468 468 MET MET A . n A 1 469 GLU 469 469 469 GLU GLU A . n A 1 470 ILE 470 470 470 ILE ILE A . n A 1 471 TRP 471 471 471 TRP TRP A . n A 1 472 LYS 472 472 472 LYS LYS A . n A 1 473 LYS 473 473 473 LYS LYS A . n A 1 474 ARG 474 474 474 ARG ARG A . n A 1 475 TRP 475 475 475 TRP TRP A . n A 1 476 ASP 476 476 476 ASP ASP A . n A 1 477 LYS 477 477 477 LYS LYS A . n A 1 478 PHE 478 478 478 PHE PHE A . n A 1 479 ILE 479 479 479 ILE ILE A . n A 1 480 ALA 480 480 480 ALA ALA A . n A 1 481 ASP 481 481 481 ASP ASP A . n A 1 482 VAL 482 482 482 VAL VAL A . n A 1 483 ALA 483 483 483 ALA ALA A . n A 1 484 THR 484 484 484 THR THR A . n A 1 485 LYS 485 485 ? ? ? A . n A 1 486 GLY 486 486 ? ? ? A . n A 1 487 SER 487 487 ? ? ? A . n A 1 488 LEU 488 488 ? ? ? A . n A 1 489 HIS 489 489 ? ? ? A . n A 1 490 HIS 490 490 ? ? ? A . n A 1 491 ILE 491 491 ? ? ? A . n A 1 492 LEU 492 492 ? ? ? A . n A 1 493 ASP 493 493 ? ? ? A . n A 1 494 ALA 494 494 ? ? ? A . n A 1 495 GLN 495 495 ? ? ? A . n A 1 496 LYS 496 496 ? ? ? A . n A 1 497 MET 497 497 ? ? ? A . n A 1 498 VAL 498 498 ? ? ? A . n A 1 499 TRP 499 499 ? ? ? A . n A 1 500 ASN 500 500 ? ? ? A . n A 1 501 HIS 501 501 ? ? ? A . n A 1 502 ARG 502 502 ? ? ? A . n A 1 503 HIS 503 503 ? ? ? A . n A 1 504 HIS 504 504 ? ? ? A . n A 1 505 HIS 505 505 ? ? ? A . n A 1 506 HIS 506 506 ? ? ? A . n A 1 507 HIS 507 507 ? ? ? A . n A 1 508 HIS 508 508 ? ? ? A . n B 1 1 GLY 1 1 ? ? ? B . n B 1 2 GLY 2 2 ? ? ? B . n B 1 3 SER 3 3 3 SER SER B . n B 1 4 ILE 4 4 4 ILE ILE B . n B 1 5 ASP 5 5 5 ASP ASP B . n B 1 6 GLU 6 6 6 GLU GLU B . n B 1 7 THR 7 7 7 THR THR B . n B 1 8 ARG 8 8 8 ARG ARG B . n B 1 9 ALA 9 9 9 ALA ALA B . n B 1 10 HIS 10 10 10 HIS HIS B . n B 1 11 LEU 11 11 11 LEU LEU B . n B 1 12 LEU 12 12 12 LEU LEU B . n B 1 13 LEU 13 13 13 LEU LEU B . n B 1 14 LYS 14 14 14 LYS LYS B . n B 1 15 GLU 15 15 15 GLU GLU B . n B 1 16 LYS 16 16 16 LYS LYS B . n B 1 17 MET 17 17 17 MET MET B . n B 1 18 MET 18 18 18 MET MET B . n B 1 19 ARG 19 19 19 ARG ARG B . n B 1 20 LEU 20 20 20 LEU LEU B . n B 1 21 GLY 21 21 21 GLY GLY B . n B 1 22 GLY 22 22 22 GLY GLY B . n B 1 23 ARG 23 23 23 ARG ARG B . n B 1 24 LEU 24 24 24 LEU LEU B . n B 1 25 VAL 25 25 25 VAL VAL B . n B 1 26 LEU 26 26 26 LEU LEU B . n B 1 27 ASN 27 27 27 ASN ASN B . n B 1 28 THR 28 28 28 THR THR B . n B 1 29 LYS 29 29 29 LYS LYS B . n B 1 30 GLU 30 30 30 GLU GLU B . n B 1 31 GLU 31 31 31 GLU GLU B . n B 1 32 LEU 32 32 32 LEU LEU B . n B 1 33 ALA 33 33 33 ALA ALA B . n B 1 34 ASN 34 34 34 ASN ASN B . n B 1 35 GLU 35 35 35 GLU GLU B . n B 1 36 ARG 36 36 36 ARG ARG B . n B 1 37 LEU 37 37 37 LEU LEU B . n B 1 38 MET 38 38 38 MET MET B . n B 1 39 THR 39 39 39 THR THR B . n B 1 40 LEU 40 40 40 LEU LEU B . n B 1 41 LYS 41 41 41 LYS LYS B . n B 1 42 ILE 42 42 42 ILE ILE B . n B 1 43 ALA 43 43 43 ALA ALA B . n B 1 44 GLU 44 44 44 GLU GLU B . n B 1 45 MET 45 45 45 MET MET B . n B 1 46 LYS 46 46 46 LYS LYS B . n B 1 47 GLU 47 47 47 GLU GLU B . n B 1 48 ALA 48 48 48 ALA ALA B . n B 1 49 MET 49 49 49 MET MET B . n B 1 50 ARG 50 50 50 ARG ARG B . n B 1 51 THR 51 51 51 THR THR B . n B 1 52 LEU 52 52 52 LEU LEU B . n B 1 53 ILE 53 53 53 ILE ILE B . n B 1 54 PHE 54 54 54 PHE PHE B . n B 1 55 PRO 55 55 55 PRO PRO B . n B 1 56 PRO 56 56 56 PRO PRO B . n B 1 57 SER 57 57 57 SER SER B . n B 1 58 MET 58 58 58 MET MET B . n B 1 59 HIS 59 59 59 HIS HIS B . n B 1 60 PHE 60 60 60 PHE PHE B . n B 1 61 PHE 61 61 61 PHE PHE B . n B 1 62 GLN 62 62 62 GLN GLN B . n B 1 63 ALA 63 63 63 ALA ALA B . n B 1 64 LYS 64 64 64 LYS LYS B . n B 1 65 HIS 65 65 65 HIS HIS B . n B 1 66 LEU 66 66 66 LEU LEU B . n B 1 67 ILE 67 67 67 ILE ILE B . n B 1 68 GLU 68 68 68 GLU GLU B . n B 1 69 ARG 69 69 69 ARG ARG B . n B 1 70 SER 70 70 70 SER SER B . n B 1 71 GLN 71 71 71 GLN GLN B . n B 1 72 VAL 72 72 72 VAL VAL B . n B 1 73 PHE 73 73 73 PHE PHE B . n B 1 74 ASN 74 74 74 ASN ASN B . n B 1 75 ILE 75 75 75 ILE ILE B . n B 1 76 LEU 76 76 76 LEU LEU B . n B 1 77 ARG 77 77 77 ARG ARG B . n B 1 78 MET 78 78 78 MET MET B . n B 1 79 MET 79 79 79 MET MET B . n B 1 80 PRO 80 80 80 PRO PRO B . n B 1 81 LYS 81 81 81 LYS LYS B . n B 1 82 GLY 82 82 82 GLY GLY B . n B 1 83 ALA 83 83 83 ALA ALA B . n B 1 84 ALA 84 84 84 ALA ALA B . n B 1 85 LEU 85 85 85 LEU LEU B . n B 1 86 HIS 86 86 86 HIS HIS B . n B 1 87 LEU 87 87 87 LEU LEU B . n B 1 88 HIS 88 88 88 HIS HIS B . n B 1 89 ASP 89 89 89 ASP ASP B . n B 1 90 ILE 90 90 90 ILE ILE B . n B 1 91 GLY 91 91 91 GLY GLY B . n B 1 92 ILE 92 92 92 ILE ILE B . n B 1 93 VAL 93 93 93 VAL VAL B . n B 1 94 THR 94 94 94 THR THR B . n B 1 95 MET 95 95 95 MET MET B . n B 1 96 ASP 96 96 96 ASP ASP B . n B 1 97 TRP 97 97 97 TRP TRP B . n B 1 98 LEU 98 98 98 LEU LEU B . n B 1 99 VAL 99 99 99 VAL VAL B . n B 1 100 ARG 100 100 100 ARG ARG B . n B 1 101 ASN 101 101 101 ASN ASN B . n B 1 102 VAL 102 102 102 VAL VAL B . n B 1 103 THR 103 103 103 THR THR B . n B 1 104 TYR 104 104 104 TYR TYR B . n B 1 105 ARG 105 105 105 ARG ARG B . n B 1 106 PRO 106 106 106 PRO PRO B . n B 1 107 HIS 107 107 107 HIS HIS B . n B 1 108 CYS 108 108 108 CYS CYS B . n B 1 109 HIS 109 109 109 HIS HIS B . n B 1 110 ILE 110 110 110 ILE ILE B . n B 1 111 CYS 111 111 111 CYS CYS B . n B 1 112 PHE 112 112 112 PHE PHE B . n B 1 113 THR 113 113 113 THR THR B . n B 1 114 PRO 114 114 114 PRO PRO B . n B 1 115 ARG 115 115 115 ARG ARG B . n B 1 116 GLY 116 116 116 GLY GLY B . n B 1 117 ILE 117 117 117 ILE ILE B . n B 1 118 MET 118 118 118 MET MET B . n B 1 119 GLN 119 119 119 GLN GLN B . n B 1 120 PHE 120 120 120 PHE PHE B . n B 1 121 ARG 121 121 121 ARG ARG B . n B 1 122 PHE 122 122 122 PHE PHE B . n B 1 123 ALA 123 123 123 ALA ALA B . n B 1 124 HIS 124 124 124 HIS HIS B . n B 1 125 PRO 125 125 125 PRO PRO B . n B 1 126 THR 126 126 126 THR THR B . n B 1 127 PRO 127 127 127 PRO PRO B . n B 1 128 ARG 128 128 128 ARG ARG B . n B 1 129 PRO 129 129 129 PRO PRO B . n B 1 130 SER 130 130 130 SER SER B . n B 1 131 GLU 131 131 131 GLU GLU B . n B 1 132 LYS 132 132 132 LYS LYS B . n B 1 133 CYS 133 133 133 CYS CYS B . n B 1 134 SER 134 134 134 SER SER B . n B 1 135 LYS 135 135 135 LYS LYS B . n B 1 136 TRP 136 136 136 TRP TRP B . n B 1 137 ILE 137 137 137 ILE ILE B . n B 1 138 LEU 138 138 138 LEU LEU B . n B 1 139 LEU 139 139 139 LEU LEU B . n B 1 140 GLU 140 140 140 GLU GLU B . n B 1 141 ASP 141 141 141 ASP ASP B . n B 1 142 TYR 142 142 142 TYR TYR B . n B 1 143 ARG 143 143 143 ARG ARG B . n B 1 144 LYS 144 144 144 LYS LYS B . n B 1 145 ARG 145 145 145 ARG ARG B . n B 1 146 VAL 146 146 146 VAL VAL B . n B 1 147 GLN 147 147 147 GLN GLN B . n B 1 148 ASN 148 148 148 ASN ASN B . n B 1 149 VAL 149 149 149 VAL VAL B . n B 1 150 THR 150 150 150 THR THR B . n B 1 151 GLU 151 151 151 GLU GLU B . n B 1 152 PHE 152 152 152 PHE PHE B . n B 1 153 ASP 153 153 153 ASP ASP B . n B 1 154 ASP 154 154 154 ASP ASP B . n B 1 155 SER 155 155 155 SER SER B . n B 1 156 LEU 156 156 156 LEU LEU B . n B 1 157 LEU 157 157 157 LEU LEU B . n B 1 158 ARG 158 158 158 ARG ARG B . n B 1 159 ASN 159 159 159 ASN ASN B . n B 1 160 PHE 160 160 160 PHE PHE B . n B 1 161 THR 161 161 161 THR THR B . n B 1 162 LEU 162 162 162 LEU LEU B . n B 1 163 VAL 163 163 163 VAL VAL B . n B 1 164 THR 164 164 164 THR THR B . n B 1 165 GLN 165 165 165 GLN GLN B . n B 1 166 HIS 166 166 166 HIS HIS B . n B 1 167 PRO 167 167 167 PRO PRO B . n B 1 168 GLU 168 168 168 GLU GLU B . n B 1 169 VAL 169 169 169 VAL VAL B . n B 1 170 ILE 170 170 170 ILE ILE B . n B 1 171 TYR 171 171 171 TYR TYR B . n B 1 172 THR 172 172 172 THR THR B . n B 1 173 ASN 173 173 173 ASN ASN B . n B 1 174 GLN 174 174 174 GLN GLN B . n B 1 175 ASN 175 175 175 ASN ASN B . n B 1 176 VAL 176 176 176 VAL VAL B . n B 1 177 VAL 177 177 177 VAL VAL B . n B 1 178 TRP 178 178 178 TRP TRP B . n B 1 179 SER 179 179 179 SER SER B . n B 1 180 LYS 180 180 180 LYS LYS B . n B 1 181 PHE 181 181 181 PHE PHE B . n B 1 182 GLU 182 182 182 GLU GLU B . n B 1 183 THR 183 183 183 THR THR B . n B 1 184 ILE 184 184 184 ILE ILE B . n B 1 185 PHE 185 185 185 PHE PHE B . n B 1 186 PHE 186 186 186 PHE PHE B . n B 1 187 THR 187 187 187 THR THR B . n B 1 188 ILE 188 188 188 ILE ILE B . n B 1 189 SER 189 189 189 SER SER B . n B 1 190 GLY 190 190 190 GLY GLY B . n B 1 191 LEU 191 191 191 LEU LEU B . n B 1 192 ILE 192 192 192 ILE ILE B . n B 1 193 HIS 193 193 193 HIS HIS B . n B 1 194 TYR 194 194 194 TYR TYR B . n B 1 195 ALA 195 195 195 ALA ALA B . n B 1 196 PRO 196 196 196 PRO PRO B . n B 1 197 VAL 197 197 197 VAL VAL B . n B 1 198 PHE 198 198 198 PHE PHE B . n B 1 199 ARG 199 199 199 ARG ARG B . n B 1 200 ASP 200 200 200 ASP ASP B . n B 1 201 TYR 201 201 201 TYR TYR B . n B 1 202 VAL 202 202 202 VAL VAL B . n B 1 203 PHE 203 203 203 PHE PHE B . n B 1 204 ARG 204 204 204 ARG ARG B . n B 1 205 SER 205 205 205 SER SER B . n B 1 206 MET 206 206 206 MET MET B . n B 1 207 GLN 207 207 207 GLN GLN B . n B 1 208 GLU 208 208 208 GLU GLU B . n B 1 209 PHE 209 209 209 PHE PHE B . n B 1 210 TYR 210 210 210 TYR TYR B . n B 1 211 GLU 211 211 211 GLU GLU B . n B 1 212 ASP 212 212 212 ASP ASP B . n B 1 213 ASN 213 213 213 ASN ASN B . n B 1 214 VAL 214 214 214 VAL VAL B . n B 1 215 LEU 215 215 215 LEU LEU B . n B 1 216 TYR 216 216 216 TYR TYR B . n B 1 217 MET 217 217 217 MET MET B . n B 1 218 GLU 218 218 218 GLU GLU B . n B 1 219 ILE 219 219 219 ILE ILE B . n B 1 220 ARG 220 220 220 ARG ARG B . n B 1 221 ALA 221 221 221 ALA ALA B . n B 1 222 ARG 222 222 222 ARG ARG B . n B 1 223 LEU 223 223 223 LEU LEU B . n B 1 224 LEU 224 224 224 LEU LEU B . n B 1 225 PRO 225 225 225 PRO PRO B . n B 1 226 VAL 226 226 226 VAL VAL B . n B 1 227 TYR 227 227 227 TYR TYR B . n B 1 228 GLU 228 228 228 GLU GLU B . n B 1 229 LEU 229 229 229 LEU LEU B . n B 1 230 SER 230 230 230 SER SER B . n B 1 231 GLY 231 231 231 GLY GLY B . n B 1 232 GLU 232 232 232 GLU GLU B . n B 1 233 HIS 233 233 233 HIS HIS B . n B 1 234 HIS 234 234 234 HIS HIS B . n B 1 235 ASP 235 235 235 ASP ASP B . n B 1 236 GLU 236 236 236 GLU GLU B . n B 1 237 GLU 237 237 237 GLU GLU B . n B 1 238 TRP 238 238 238 TRP TRP B . n B 1 239 SER 239 239 239 SER SER B . n B 1 240 VAL 240 240 240 VAL VAL B . n B 1 241 LYS 241 241 241 LYS LYS B . n B 1 242 THR 242 242 242 THR THR B . n B 1 243 TYR 243 243 243 TYR TYR B . n B 1 244 GLN 244 244 244 GLN GLN B . n B 1 245 GLU 245 245 245 GLU GLU B . n B 1 246 VAL 246 246 246 VAL VAL B . n B 1 247 ALA 247 247 247 ALA ALA B . n B 1 248 GLN 248 248 248 GLN GLN B . n B 1 249 LYS 249 249 249 LYS LYS B . n B 1 250 PHE 250 250 250 PHE PHE B . n B 1 251 VAL 251 251 251 VAL VAL B . n B 1 252 GLU 252 252 252 GLU GLU B . n B 1 253 THR 253 253 253 THR THR B . n B 1 254 HIS 254 254 254 HIS HIS B . n B 1 255 PRO 255 255 255 PRO PRO B . n B 1 256 GLU 256 256 256 GLU GLU B . n B 1 257 PHE 257 257 257 PHE PHE B . n B 1 258 ILE 258 258 258 ILE ILE B . n B 1 259 GLY 259 259 259 GLY GLY B . n B 1 260 ILE 260 260 260 ILE ILE B . n B 1 261 LYS 261 261 261 LYS LYS B . n B 1 262 ILE 262 262 262 ILE ILE B . n B 1 263 ILE 263 263 263 ILE ILE B . n B 1 264 TYR 264 264 264 TYR TYR B . n B 1 265 SER 265 265 265 SER SER B . n B 1 266 ASP 266 266 266 ASP ASP B . n B 1 267 HIS 267 267 267 HIS HIS B . n B 1 268 ARG 268 268 268 ARG ARG B . n B 1 269 SER 269 269 269 SER SER B . n B 1 270 LYS 270 270 270 LYS LYS B . n B 1 271 ASP 271 271 271 ASP ASP B . n B 1 272 VAL 272 272 272 VAL VAL B . n B 1 273 ALA 273 273 273 ALA ALA B . n B 1 274 VAL 274 274 274 VAL VAL B . n B 1 275 ILE 275 275 275 ILE ILE B . n B 1 276 ALA 276 276 276 ALA ALA B . n B 1 277 GLU 277 277 277 GLU GLU B . n B 1 278 SER 278 278 278 SER SER B . n B 1 279 ILE 279 279 279 ILE ILE B . n B 1 280 ARG 280 280 280 ARG ARG B . n B 1 281 MET 281 281 281 MET MET B . n B 1 282 ALA 282 282 282 ALA ALA B . n B 1 283 MET 283 283 283 MET MET B . n B 1 284 GLY 284 284 284 GLY GLY B . n B 1 285 LEU 285 285 285 LEU LEU B . n B 1 286 ARG 286 286 286 ARG ARG B . n B 1 287 ILE 287 287 287 ILE ILE B . n B 1 288 LYS 288 288 288 LYS LYS B . n B 1 289 PHE 289 289 289 PHE PHE B . n B 1 290 PRO 290 290 290 PRO PRO B . n B 1 291 THR 291 291 291 THR THR B . n B 1 292 VAL 292 292 292 VAL VAL B . n B 1 293 VAL 293 293 293 VAL VAL B . n B 1 294 ALA 294 294 294 ALA ALA B . n B 1 295 GLY 295 295 295 GLY GLY B . n B 1 296 PHE 296 296 296 PHE PHE B . n B 1 297 ASP 297 297 297 ASP ASP B . n B 1 298 LEU 298 298 298 LEU LEU B . n B 1 299 VAL 299 299 299 VAL VAL B . n B 1 300 GLY 300 300 300 GLY GLY B . n B 1 301 HIS 301 301 301 HIS HIS B . n B 1 302 GLU 302 302 302 GLU GLU B . n B 1 303 ASP 303 303 303 ASP ASP B . n B 1 304 THR 304 304 304 THR THR B . n B 1 305 GLY 305 305 305 GLY GLY B . n B 1 306 HIS 306 306 306 HIS HIS B . n B 1 307 SER 307 307 307 SER SER B . n B 1 308 LEU 308 308 308 LEU LEU B . n B 1 309 HIS 309 309 309 HIS HIS B . n B 1 310 ASP 310 310 310 ASP ASP B . n B 1 311 TYR 311 311 311 TYR TYR B . n B 1 312 LYS 312 312 312 LYS LYS B . n B 1 313 GLU 313 313 313 GLU GLU B . n B 1 314 ALA 314 314 314 ALA ALA B . n B 1 315 LEU 315 315 315 LEU LEU B . n B 1 316 MET 316 316 316 MET MET B . n B 1 317 ILE 317 317 317 ILE ILE B . n B 1 318 PRO 318 318 318 PRO PRO B . n B 1 319 ALA 319 319 319 ALA ALA B . n B 1 320 LYS 320 320 320 LYS LYS B . n B 1 321 ASP 321 321 321 ASP ASP B . n B 1 322 GLY 322 322 322 GLY GLY B . n B 1 323 VAL 323 323 323 VAL VAL B . n B 1 324 LYS 324 324 324 LYS LYS B . n B 1 325 LEU 325 325 325 LEU LEU B . n B 1 326 PRO 326 326 326 PRO PRO B . n B 1 327 TYR 327 327 327 TYR TYR B . n B 1 328 PHE 328 328 328 PHE PHE B . n B 1 329 PHE 329 329 329 PHE PHE B . n B 1 330 HIS 330 330 330 HIS HIS B . n B 1 331 ALA 331 331 331 ALA ALA B . n B 1 332 GLY 332 332 332 GLY GLY B . n B 1 333 GLU 333 333 333 GLU GLU B . n B 1 334 THR 334 334 334 THR THR B . n B 1 335 ASP 335 335 335 ASP ASP B . n B 1 336 TRP 336 336 336 TRP TRP B . n B 1 337 GLN 337 337 337 GLN GLN B . n B 1 338 GLY 338 338 338 GLY GLY B . n B 1 339 THR 339 339 339 THR THR B . n B 1 340 SER 340 340 340 SER SER B . n B 1 341 ILE 341 341 341 ILE ILE B . n B 1 342 ASP 342 342 342 ASP ASP B . n B 1 343 ARG 343 343 343 ARG ARG B . n B 1 344 ASN 344 344 344 ASN ASN B . n B 1 345 ILE 345 345 345 ILE ILE B . n B 1 346 LEU 346 346 346 LEU LEU B . n B 1 347 ASP 347 347 347 ASP ASP B . n B 1 348 ALA 348 348 348 ALA ALA B . n B 1 349 LEU 349 349 349 LEU LEU B . n B 1 350 MET 350 350 350 MET MET B . n B 1 351 LEU 351 351 351 LEU LEU B . n B 1 352 ASN 352 352 352 ASN ASN B . n B 1 353 THR 353 353 353 THR THR B . n B 1 354 THR 354 354 354 THR THR B . n B 1 355 ARG 355 355 355 ARG ARG B . n B 1 356 ILE 356 356 356 ILE ILE B . n B 1 357 GLY 357 357 357 GLY GLY B . n B 1 358 HIS 358 358 358 HIS HIS B . n B 1 359 GLY 359 359 359 GLY GLY B . n B 1 360 PHE 360 360 360 PHE PHE B . n B 1 361 ALA 361 361 361 ALA ALA B . n B 1 362 LEU 362 362 362 LEU LEU B . n B 1 363 SER 363 363 363 SER SER B . n B 1 364 LYS 364 364 364 LYS LYS B . n B 1 365 HIS 365 365 365 HIS HIS B . n B 1 366 PRO 366 366 366 PRO PRO B . n B 1 367 ALA 367 367 367 ALA ALA B . n B 1 368 VAL 368 368 368 VAL VAL B . n B 1 369 ARG 369 369 369 ARG ARG B . n B 1 370 THR 370 370 370 THR THR B . n B 1 371 TYR 371 371 371 TYR TYR B . n B 1 372 SER 372 372 372 SER SER B . n B 1 373 TRP 373 373 373 TRP TRP B . n B 1 374 LYS 374 374 374 LYS LYS B . n B 1 375 LYS 375 375 375 LYS LYS B . n B 1 376 ASP 376 376 376 ASP ASP B . n B 1 377 ILE 377 377 377 ILE ILE B . n B 1 378 PRO 378 378 378 PRO PRO B . n B 1 379 ILE 379 379 379 ILE ILE B . n B 1 380 GLU 380 380 380 GLU GLU B . n B 1 381 VAL 381 381 381 VAL VAL B . n B 1 382 CYS 382 382 382 CYS CYS B . n B 1 383 PRO 383 383 383 PRO PRO B . n B 1 384 ILE 384 384 384 ILE ILE B . n B 1 385 SER 385 385 385 SER SER B . n B 1 386 ASN 386 386 386 ASN ASN B . n B 1 387 GLN 387 387 387 GLN GLN B . n B 1 388 VAL 388 388 388 VAL VAL B . n B 1 389 LEU 389 389 389 LEU LEU B . n B 1 390 LYS 390 390 390 LYS LYS B . n B 1 391 LEU 391 391 391 LEU LEU B . n B 1 392 VAL 392 392 392 VAL VAL B . n B 1 393 SER 393 393 393 SER SER B . n B 1 394 ASP 394 394 394 ASP ASP B . n B 1 395 LEU 395 395 395 LEU LEU B . n B 1 396 ARG 396 396 396 ARG ARG B . n B 1 397 ASN 397 397 397 ASN ASN B . n B 1 398 HIS 398 398 398 HIS HIS B . n B 1 399 PRO 399 399 399 PRO PRO B . n B 1 400 VAL 400 400 400 VAL VAL B . n B 1 401 ALA 401 401 401 ALA ALA B . n B 1 402 THR 402 402 402 THR THR B . n B 1 403 LEU 403 403 403 LEU LEU B . n B 1 404 MET 404 404 404 MET MET B . n B 1 405 ALA 405 405 405 ALA ALA B . n B 1 406 THR 406 406 406 THR THR B . n B 1 407 GLY 407 407 407 GLY GLY B . n B 1 408 HIS 408 408 408 HIS HIS B . n B 1 409 PRO 409 409 409 PRO PRO B . n B 1 410 MET 410 410 410 MET MET B . n B 1 411 VAL 411 411 411 VAL VAL B . n B 1 412 ILE 412 412 412 ILE ILE B . n B 1 413 SER 413 413 413 SER SER B . n B 1 414 SER 414 414 414 SER SER B . n B 1 415 ASP 415 415 415 ASP ASP B . n B 1 416 ASP 416 416 416 ASP ASP B . n B 1 417 PRO 417 417 417 PRO PRO B . n B 1 418 ALA 418 418 418 ALA ALA B . n B 1 419 MET 419 419 419 MET MET B . n B 1 420 PHE 420 420 420 PHE PHE B . n B 1 421 GLY 421 421 421 GLY GLY B . n B 1 422 ALA 422 422 422 ALA ALA B . n B 1 423 LYS 423 423 423 LYS LYS B . n B 1 424 GLY 424 424 424 GLY GLY B . n B 1 425 LEU 425 425 425 LEU LEU B . n B 1 426 SER 426 426 426 SER SER B . n B 1 427 TYR 427 427 427 TYR TYR B . n B 1 428 ASP 428 428 428 ASP ASP B . n B 1 429 PHE 429 429 429 PHE PHE B . n B 1 430 TYR 430 430 430 TYR TYR B . n B 1 431 GLU 431 431 431 GLU GLU B . n B 1 432 VAL 432 432 432 VAL VAL B . n B 1 433 PHE 433 433 433 PHE PHE B . n B 1 434 MET 434 434 434 MET MET B . n B 1 435 GLY 435 435 435 GLY GLY B . n B 1 436 ILE 436 436 436 ILE ILE B . n B 1 437 GLY 437 437 437 GLY GLY B . n B 1 438 GLY 438 438 438 GLY GLY B . n B 1 439 MET 439 439 439 MET MET B . n B 1 440 LYS 440 440 440 LYS LYS B . n B 1 441 ALA 441 441 441 ALA ALA B . n B 1 442 ASP 442 442 442 ASP ASP B . n B 1 443 LEU 443 443 443 LEU LEU B . n B 1 444 ARG 444 444 444 ARG ARG B . n B 1 445 THR 445 445 445 THR THR B . n B 1 446 LEU 446 446 446 LEU LEU B . n B 1 447 LYS 447 447 447 LYS LYS B . n B 1 448 GLN 448 448 448 GLN GLN B . n B 1 449 LEU 449 449 449 LEU LEU B . n B 1 450 ALA 450 450 450 ALA ALA B . n B 1 451 MET 451 451 451 MET MET B . n B 1 452 ASN 452 452 452 ASN ASN B . n B 1 453 SER 453 453 453 SER SER B . n B 1 454 ILE 454 454 454 ILE ILE B . n B 1 455 LYS 455 455 455 LYS LYS B . n B 1 456 TYR 456 456 456 TYR TYR B . n B 1 457 SER 457 457 457 SER SER B . n B 1 458 THR 458 458 458 THR THR B . n B 1 459 LEU 459 459 459 LEU LEU B . n B 1 460 LEU 460 460 460 LEU LEU B . n B 1 461 GLU 461 461 461 GLU GLU B . n B 1 462 SER 462 462 462 SER SER B . n B 1 463 GLU 463 463 463 GLU GLU B . n B 1 464 LYS 464 464 464 LYS LYS B . n B 1 465 ASN 465 465 465 ASN ASN B . n B 1 466 THR 466 466 466 THR THR B . n B 1 467 PHE 467 467 467 PHE PHE B . n B 1 468 MET 468 468 468 MET MET B . n B 1 469 GLU 469 469 469 GLU GLU B . n B 1 470 ILE 470 470 470 ILE ILE B . n B 1 471 TRP 471 471 471 TRP TRP B . n B 1 472 LYS 472 472 472 LYS LYS B . n B 1 473 LYS 473 473 473 LYS LYS B . n B 1 474 ARG 474 474 474 ARG ARG B . n B 1 475 TRP 475 475 475 TRP TRP B . n B 1 476 ASP 476 476 476 ASP ASP B . n B 1 477 LYS 477 477 477 LYS LYS B . n B 1 478 PHE 478 478 478 PHE PHE B . n B 1 479 ILE 479 479 479 ILE ILE B . n B 1 480 ALA 480 480 480 ALA ALA B . n B 1 481 ASP 481 481 481 ASP ASP B . n B 1 482 VAL 482 482 482 VAL VAL B . n B 1 483 ALA 483 483 483 ALA ALA B . n B 1 484 THR 484 484 484 THR THR B . n B 1 485 LYS 485 485 ? ? ? B . n B 1 486 GLY 486 486 ? ? ? B . n B 1 487 SER 487 487 ? ? ? B . n B 1 488 LEU 488 488 ? ? ? B . n B 1 489 HIS 489 489 ? ? ? B . n B 1 490 HIS 490 490 ? ? ? B . n B 1 491 ILE 491 491 ? ? ? B . n B 1 492 LEU 492 492 ? ? ? B . n B 1 493 ASP 493 493 ? ? ? B . n B 1 494 ALA 494 494 ? ? ? B . n B 1 495 GLN 495 495 ? ? ? B . n B 1 496 LYS 496 496 ? ? ? B . n B 1 497 MET 497 497 ? ? ? B . n B 1 498 VAL 498 498 ? ? ? B . n B 1 499 TRP 499 499 ? ? ? B . n B 1 500 ASN 500 500 ? ? ? B . n B 1 501 HIS 501 501 ? ? ? B . n B 1 502 ARG 502 502 ? ? ? B . n B 1 503 HIS 503 503 ? ? ? B . n B 1 504 HIS 504 504 ? ? ? B . n B 1 505 HIS 505 505 ? ? ? B . n B 1 506 HIS 506 506 ? ? ? B . n B 1 507 HIS 507 507 ? ? ? B . n B 1 508 HIS 508 508 ? ? ? B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 NAG 1 550 550 NAG NAG A . D 2 NAG 1 650 650 NAG NAG A . E 2 NAG 1 750 750 NAG NAG A . F 3 ZN 1 850 850 ZN ZN A . G 4 EDO 1 950 950 EDO EDO A . H 5 UNX 1 951 951 UNX UNX A . I 2 NAG 1 550 550 NAG NAG B . J 2 NAG 1 650 650 NAG NAG B . K 2 NAG 1 750 750 NAG NAG B . L 3 ZN 1 850 850 ZN ZN B . M 4 EDO 1 950 950 EDO EDO B . N 5 UNX 1 951 951 UNX UNX B . O 6 HOH 1 509 1 HOH HOH A . O 6 HOH 2 510 510 HOH HOH A . O 6 HOH 3 511 511 HOH HOH A . O 6 HOH 4 512 3 HOH HOH A . O 6 HOH 5 513 4 HOH HOH A . O 6 HOH 6 514 514 HOH HOH A . O 6 HOH 7 515 10 HOH HOH A . O 6 HOH 8 516 12 HOH HOH A . O 6 HOH 9 517 517 HOH HOH A . O 6 HOH 10 518 518 HOH HOH A . O 6 HOH 11 519 13 HOH HOH A . O 6 HOH 12 520 520 HOH HOH A . O 6 HOH 13 521 521 HOH HOH A . O 6 HOH 14 522 522 HOH HOH A . O 6 HOH 15 523 16 HOH HOH A . O 6 HOH 16 524 19 HOH HOH A . O 6 HOH 17 525 22 HOH HOH A . O 6 HOH 18 526 23 HOH HOH A . O 6 HOH 19 527 527 HOH HOH A . O 6 HOH 20 528 24 HOH HOH A . O 6 HOH 21 529 25 HOH HOH A . O 6 HOH 22 530 530 HOH HOH A . O 6 HOH 23 531 531 HOH HOH A . O 6 HOH 24 532 26 HOH HOH A . O 6 HOH 25 533 28 HOH HOH A . O 6 HOH 26 534 29 HOH HOH A . O 6 HOH 27 535 535 HOH HOH A . O 6 HOH 28 536 536 HOH HOH A . O 6 HOH 29 537 30 HOH HOH A . O 6 HOH 30 538 538 HOH HOH A . O 6 HOH 31 539 32 HOH HOH A . O 6 HOH 32 540 36 HOH HOH A . O 6 HOH 33 541 38 HOH HOH A . O 6 HOH 34 542 42 HOH HOH A . O 6 HOH 35 543 543 HOH HOH A . O 6 HOH 36 544 46 HOH HOH A . O 6 HOH 37 545 47 HOH HOH A . O 6 HOH 38 546 48 HOH HOH A . O 6 HOH 39 547 49 HOH HOH A . O 6 HOH 40 548 52 HOH HOH A . O 6 HOH 41 549 549 HOH HOH A . O 6 HOH 42 551 54 HOH HOH A . O 6 HOH 43 552 552 HOH HOH A . O 6 HOH 44 553 55 HOH HOH A . O 6 HOH 45 554 56 HOH HOH A . O 6 HOH 46 555 555 HOH HOH A . O 6 HOH 47 556 556 HOH HOH A . O 6 HOH 48 557 557 HOH HOH A . O 6 HOH 49 558 58 HOH HOH A . O 6 HOH 50 559 559 HOH HOH A . O 6 HOH 51 560 60 HOH HOH A . O 6 HOH 52 561 61 HOH HOH A . O 6 HOH 53 562 64 HOH HOH A . O 6 HOH 54 563 65 HOH HOH A . O 6 HOH 55 564 564 HOH HOH A . O 6 HOH 56 565 66 HOH HOH A . O 6 HOH 57 566 566 HOH HOH A . O 6 HOH 58 567 567 HOH HOH A . O 6 HOH 59 568 568 HOH HOH A . O 6 HOH 60 569 68 HOH HOH A . O 6 HOH 61 570 69 HOH HOH A . O 6 HOH 62 571 571 HOH HOH A . O 6 HOH 63 572 572 HOH HOH A . O 6 HOH 64 573 573 HOH HOH A . O 6 HOH 65 574 73 HOH HOH A . O 6 HOH 66 575 76 HOH HOH A . O 6 HOH 67 576 77 HOH HOH A . O 6 HOH 68 577 79 HOH HOH A . O 6 HOH 69 578 578 HOH HOH A . O 6 HOH 70 579 83 HOH HOH A . O 6 HOH 71 580 84 HOH HOH A . O 6 HOH 72 581 581 HOH HOH A . O 6 HOH 73 582 87 HOH HOH A . O 6 HOH 74 583 583 HOH HOH A . O 6 HOH 75 584 90 HOH HOH A . O 6 HOH 76 585 93 HOH HOH A . O 6 HOH 77 586 586 HOH HOH A . O 6 HOH 78 587 96 HOH HOH A . O 6 HOH 79 588 97 HOH HOH A . O 6 HOH 80 589 99 HOH HOH A . O 6 HOH 81 590 590 HOH HOH A . O 6 HOH 82 591 591 HOH HOH A . O 6 HOH 83 592 592 HOH HOH A . O 6 HOH 84 593 102 HOH HOH A . O 6 HOH 85 594 594 HOH HOH A . O 6 HOH 86 595 595 HOH HOH A . O 6 HOH 87 596 596 HOH HOH A . O 6 HOH 88 597 104 HOH HOH A . O 6 HOH 89 598 105 HOH HOH A . O 6 HOH 90 599 106 HOH HOH A . O 6 HOH 91 600 108 HOH HOH A . O 6 HOH 92 601 601 HOH HOH A . O 6 HOH 93 602 602 HOH HOH A . O 6 HOH 94 603 109 HOH HOH A . O 6 HOH 95 604 110 HOH HOH A . O 6 HOH 96 605 111 HOH HOH A . O 6 HOH 97 606 606 HOH HOH A . O 6 HOH 98 607 607 HOH HOH A . O 6 HOH 99 608 608 HOH HOH A . O 6 HOH 100 610 610 HOH HOH A . O 6 HOH 101 611 611 HOH HOH A . O 6 HOH 102 612 113 HOH HOH A . O 6 HOH 103 613 115 HOH HOH A . O 6 HOH 104 614 117 HOH HOH A . O 6 HOH 105 615 121 HOH HOH A . O 6 HOH 106 616 616 HOH HOH A . O 6 HOH 107 617 123 HOH HOH A . O 6 HOH 108 618 125 HOH HOH A . O 6 HOH 109 619 619 HOH HOH A . O 6 HOH 110 620 620 HOH HOH A . O 6 HOH 111 621 127 HOH HOH A . O 6 HOH 112 622 129 HOH HOH A . O 6 HOH 113 623 132 HOH HOH A . O 6 HOH 114 624 133 HOH HOH A . O 6 HOH 115 625 625 HOH HOH A . O 6 HOH 116 626 136 HOH HOH A . O 6 HOH 117 627 137 HOH HOH A . O 6 HOH 118 628 628 HOH HOH A . O 6 HOH 119 629 138 HOH HOH A . O 6 HOH 120 630 141 HOH HOH A . O 6 HOH 121 631 631 HOH HOH A . O 6 HOH 122 632 145 HOH HOH A . O 6 HOH 123 633 633 HOH HOH A . O 6 HOH 124 634 146 HOH HOH A . O 6 HOH 125 635 147 HOH HOH A . O 6 HOH 126 636 148 HOH HOH A . O 6 HOH 127 637 150 HOH HOH A . O 6 HOH 128 638 638 HOH HOH A . O 6 HOH 129 639 639 HOH HOH A . O 6 HOH 130 640 640 HOH HOH A . O 6 HOH 131 641 152 HOH HOH A . O 6 HOH 132 642 642 HOH HOH A . O 6 HOH 133 643 643 HOH HOH A . O 6 HOH 134 644 644 HOH HOH A . O 6 HOH 135 645 645 HOH HOH A . O 6 HOH 136 646 646 HOH HOH A . O 6 HOH 137 647 647 HOH HOH A . O 6 HOH 138 648 648 HOH HOH A . O 6 HOH 139 649 155 HOH HOH A . O 6 HOH 140 651 159 HOH HOH A . O 6 HOH 141 652 161 HOH HOH A . O 6 HOH 142 653 653 HOH HOH A . O 6 HOH 143 654 165 HOH HOH A . O 6 HOH 144 655 655 HOH HOH A . O 6 HOH 145 656 656 HOH HOH A . O 6 HOH 146 657 166 HOH HOH A . O 6 HOH 147 658 169 HOH HOH A . O 6 HOH 148 659 171 HOH HOH A . O 6 HOH 149 660 660 HOH HOH A . O 6 HOH 150 661 172 HOH HOH A . O 6 HOH 151 662 662 HOH HOH A . O 6 HOH 152 663 174 HOH HOH A . O 6 HOH 153 664 664 HOH HOH A . O 6 HOH 154 665 175 HOH HOH A . O 6 HOH 155 666 666 HOH HOH A . O 6 HOH 156 667 667 HOH HOH A . O 6 HOH 157 668 668 HOH HOH A . O 6 HOH 158 669 176 HOH HOH A . O 6 HOH 159 670 670 HOH HOH A . O 6 HOH 160 671 181 HOH HOH A . O 6 HOH 161 672 672 HOH HOH A . O 6 HOH 162 673 185 HOH HOH A . O 6 HOH 163 674 186 HOH HOH A . O 6 HOH 164 675 675 HOH HOH A . O 6 HOH 165 676 187 HOH HOH A . O 6 HOH 166 677 192 HOH HOH A . O 6 HOH 167 678 194 HOH HOH A . O 6 HOH 168 679 195 HOH HOH A . O 6 HOH 169 680 199 HOH HOH A . O 6 HOH 170 681 202 HOH HOH A . O 6 HOH 171 682 203 HOH HOH A . O 6 HOH 172 683 683 HOH HOH A . O 6 HOH 173 684 684 HOH HOH A . O 6 HOH 174 685 685 HOH HOH A . O 6 HOH 175 686 204 HOH HOH A . O 6 HOH 176 687 206 HOH HOH A . O 6 HOH 177 688 207 HOH HOH A . O 6 HOH 178 689 689 HOH HOH A . O 6 HOH 179 690 690 HOH HOH A . O 6 HOH 180 691 691 HOH HOH A . O 6 HOH 181 692 209 HOH HOH A . O 6 HOH 182 693 210 HOH HOH A . O 6 HOH 183 694 694 HOH HOH A . O 6 HOH 184 695 212 HOH HOH A . O 6 HOH 185 696 696 HOH HOH A . O 6 HOH 186 697 213 HOH HOH A . O 6 HOH 187 698 216 HOH HOH A . O 6 HOH 188 699 699 HOH HOH A . O 6 HOH 189 700 222 HOH HOH A . O 6 HOH 190 701 224 HOH HOH A . O 6 HOH 191 702 226 HOH HOH A . O 6 HOH 192 703 227 HOH HOH A . O 6 HOH 193 704 229 HOH HOH A . O 6 HOH 194 705 705 HOH HOH A . O 6 HOH 195 706 706 HOH HOH A . O 6 HOH 196 707 230 HOH HOH A . O 6 HOH 197 708 708 HOH HOH A . O 6 HOH 198 709 232 HOH HOH A . O 6 HOH 199 710 234 HOH HOH A . O 6 HOH 200 711 236 HOH HOH A . O 6 HOH 201 712 239 HOH HOH A . O 6 HOH 202 713 243 HOH HOH A . O 6 HOH 203 714 244 HOH HOH A . O 6 HOH 204 715 245 HOH HOH A . O 6 HOH 205 716 246 HOH HOH A . O 6 HOH 206 717 248 HOH HOH A . O 6 HOH 207 718 718 HOH HOH A . O 6 HOH 208 719 249 HOH HOH A . O 6 HOH 209 720 250 HOH HOH A . O 6 HOH 210 721 251 HOH HOH A . O 6 HOH 211 722 256 HOH HOH A . O 6 HOH 212 723 259 HOH HOH A . O 6 HOH 213 724 260 HOH HOH A . O 6 HOH 214 725 725 HOH HOH A . O 6 HOH 215 726 726 HOH HOH A . O 6 HOH 216 727 727 HOH HOH A . O 6 HOH 217 728 262 HOH HOH A . O 6 HOH 218 729 263 HOH HOH A . O 6 HOH 219 730 264 HOH HOH A . O 6 HOH 220 731 731 HOH HOH A . O 6 HOH 221 732 265 HOH HOH A . O 6 HOH 222 733 268 HOH HOH A . O 6 HOH 223 734 734 HOH HOH A . O 6 HOH 224 735 269 HOH HOH A . O 6 HOH 225 736 736 HOH HOH A . O 6 HOH 226 737 271 HOH HOH A . O 6 HOH 227 738 738 HOH HOH A . O 6 HOH 228 739 273 HOH HOH A . O 6 HOH 229 740 275 HOH HOH A . O 6 HOH 230 741 277 HOH HOH A . O 6 HOH 231 742 279 HOH HOH A . O 6 HOH 232 743 281 HOH HOH A . O 6 HOH 233 744 284 HOH HOH A . O 6 HOH 234 745 745 HOH HOH A . O 6 HOH 235 746 746 HOH HOH A . O 6 HOH 236 747 747 HOH HOH A . O 6 HOH 237 748 748 HOH HOH A . O 6 HOH 238 749 749 HOH HOH A . O 6 HOH 239 751 285 HOH HOH A . O 6 HOH 240 752 752 HOH HOH A . O 6 HOH 241 753 287 HOH HOH A . O 6 HOH 242 754 288 HOH HOH A . O 6 HOH 243 755 289 HOH HOH A . O 6 HOH 244 756 292 HOH HOH A . O 6 HOH 245 757 293 HOH HOH A . O 6 HOH 246 758 297 HOH HOH A . O 6 HOH 247 759 759 HOH HOH A . O 6 HOH 248 760 760 HOH HOH A . O 6 HOH 249 761 298 HOH HOH A . O 6 HOH 250 762 300 HOH HOH A . O 6 HOH 251 763 302 HOH HOH A . O 6 HOH 252 764 304 HOH HOH A . O 6 HOH 253 765 765 HOH HOH A . O 6 HOH 254 766 766 HOH HOH A . O 6 HOH 255 767 767 HOH HOH A . O 6 HOH 256 768 308 HOH HOH A . O 6 HOH 257 769 769 HOH HOH A . O 6 HOH 258 770 309 HOH HOH A . O 6 HOH 259 771 311 HOH HOH A . O 6 HOH 260 772 772 HOH HOH A . O 6 HOH 261 773 314 HOH HOH A . O 6 HOH 262 774 318 HOH HOH A . O 6 HOH 263 775 775 HOH HOH A . O 6 HOH 264 776 321 HOH HOH A . O 6 HOH 265 777 322 HOH HOH A . O 6 HOH 266 778 323 HOH HOH A . O 6 HOH 267 779 324 HOH HOH A . O 6 HOH 268 780 780 HOH HOH A . O 6 HOH 269 781 325 HOH HOH A . O 6 HOH 270 782 326 HOH HOH A . O 6 HOH 271 783 327 HOH HOH A . O 6 HOH 272 784 784 HOH HOH A . O 6 HOH 273 785 328 HOH HOH A . O 6 HOH 274 786 329 HOH HOH A . O 6 HOH 275 787 787 HOH HOH A . O 6 HOH 276 788 332 HOH HOH A . O 6 HOH 277 789 333 HOH HOH A . O 6 HOH 278 790 790 HOH HOH A . O 6 HOH 279 791 335 HOH HOH A . O 6 HOH 280 792 337 HOH HOH A . O 6 HOH 281 793 339 HOH HOH A . O 6 HOH 282 794 340 HOH HOH A . O 6 HOH 283 795 343 HOH HOH A . O 6 HOH 284 796 344 HOH HOH A . O 6 HOH 285 797 797 HOH HOH A . O 6 HOH 286 798 347 HOH HOH A . O 6 HOH 287 799 358 HOH HOH A . O 6 HOH 288 800 800 HOH HOH A . O 6 HOH 289 801 359 HOH HOH A . O 6 HOH 290 802 361 HOH HOH A . O 6 HOH 291 803 369 HOH HOH A . O 6 HOH 292 804 371 HOH HOH A . O 6 HOH 293 805 376 HOH HOH A . O 6 HOH 294 806 380 HOH HOH A . O 6 HOH 295 807 381 HOH HOH A . O 6 HOH 296 808 382 HOH HOH A . O 6 HOH 297 809 383 HOH HOH A . O 6 HOH 298 810 384 HOH HOH A . O 6 HOH 299 811 811 HOH HOH A . O 6 HOH 300 812 812 HOH HOH A . O 6 HOH 301 813 813 HOH HOH A . O 6 HOH 302 814 385 HOH HOH A . O 6 HOH 303 815 390 HOH HOH A . O 6 HOH 304 816 393 HOH HOH A . O 6 HOH 305 817 394 HOH HOH A . O 6 HOH 306 818 818 HOH HOH A . O 6 HOH 307 819 397 HOH HOH A . O 6 HOH 308 820 820 HOH HOH A . O 6 HOH 309 821 821 HOH HOH A . O 6 HOH 310 822 398 HOH HOH A . O 6 HOH 311 823 823 HOH HOH A . O 6 HOH 312 824 824 HOH HOH A . O 6 HOH 313 825 825 HOH HOH A . O 6 HOH 314 826 826 HOH HOH A . O 6 HOH 315 827 401 HOH HOH A . O 6 HOH 316 828 828 HOH HOH A . O 6 HOH 317 829 402 HOH HOH A . O 6 HOH 318 830 830 HOH HOH A . O 6 HOH 319 831 831 HOH HOH A . O 6 HOH 320 832 832 HOH HOH A . O 6 HOH 321 833 833 HOH HOH A . O 6 HOH 322 834 404 HOH HOH A . O 6 HOH 323 835 835 HOH HOH A . O 6 HOH 324 836 836 HOH HOH A . O 6 HOH 325 837 837 HOH HOH A . O 6 HOH 326 838 408 HOH HOH A . O 6 HOH 327 839 409 HOH HOH A . O 6 HOH 328 840 411 HOH HOH A . O 6 HOH 329 841 841 HOH HOH A . O 6 HOH 330 842 412 HOH HOH A . O 6 HOH 331 843 843 HOH HOH A . O 6 HOH 332 844 844 HOH HOH A . O 6 HOH 333 845 845 HOH HOH A . O 6 HOH 334 846 846 HOH HOH A . O 6 HOH 335 847 847 HOH HOH A . O 6 HOH 336 848 848 HOH HOH A . O 6 HOH 337 849 414 HOH HOH A . O 6 HOH 338 851 423 HOH HOH A . O 6 HOH 339 852 424 HOH HOH A . O 6 HOH 340 853 425 HOH HOH A . O 6 HOH 341 854 430 HOH HOH A . O 6 HOH 342 855 431 HOH HOH A . O 6 HOH 343 856 434 HOH HOH A . O 6 HOH 344 857 435 HOH HOH A . O 6 HOH 345 858 436 HOH HOH A . O 6 HOH 346 859 439 HOH HOH A . O 6 HOH 347 860 440 HOH HOH A . O 6 HOH 348 861 445 HOH HOH A . O 6 HOH 349 862 447 HOH HOH A . O 6 HOH 350 863 448 HOH HOH A . O 6 HOH 351 864 450 HOH HOH A . O 6 HOH 352 865 451 HOH HOH A . O 6 HOH 353 866 452 HOH HOH A . O 6 HOH 354 867 454 HOH HOH A . O 6 HOH 355 868 455 HOH HOH A . O 6 HOH 356 869 457 HOH HOH A . O 6 HOH 357 870 458 HOH HOH A . O 6 HOH 358 871 459 HOH HOH A . O 6 HOH 359 872 461 HOH HOH A . O 6 HOH 360 873 464 HOH HOH A . O 6 HOH 361 874 467 HOH HOH A . O 6 HOH 362 875 475 HOH HOH A . O 6 HOH 363 876 477 HOH HOH A . O 6 HOH 364 877 479 HOH HOH A . O 6 HOH 365 878 480 HOH HOH A . O 6 HOH 366 879 481 HOH HOH A . O 6 HOH 367 880 483 HOH HOH A . O 6 HOH 368 881 485 HOH HOH A . O 6 HOH 369 882 486 HOH HOH A . O 6 HOH 370 883 487 HOH HOH A . O 6 HOH 371 884 488 HOH HOH A . O 6 HOH 372 885 494 HOH HOH A . O 6 HOH 373 886 500 HOH HOH A . O 6 HOH 374 887 501 HOH HOH A . O 6 HOH 375 888 502 HOH HOH A . O 6 HOH 376 889 503 HOH HOH A . O 6 HOH 377 890 504 HOH HOH A . O 6 HOH 378 891 506 HOH HOH A . O 6 HOH 379 892 507 HOH HOH A . O 6 HOH 380 893 508 HOH HOH A . O 6 HOH 381 894 550 HOH HOH A . O 6 HOH 382 895 650 HOH HOH A . O 6 HOH 383 896 850 HOH HOH A . P 6 HOH 1 509 509 HOH HOH B . P 6 HOH 2 510 2 HOH HOH B . P 6 HOH 3 511 7 HOH HOH B . P 6 HOH 4 512 512 HOH HOH B . P 6 HOH 5 513 513 HOH HOH B . P 6 HOH 6 514 8 HOH HOH B . P 6 HOH 7 515 515 HOH HOH B . P 6 HOH 8 516 516 HOH HOH B . P 6 HOH 9 517 9 HOH HOH B . P 6 HOH 10 518 11 HOH HOH B . P 6 HOH 11 519 14 HOH HOH B . P 6 HOH 12 520 15 HOH HOH B . P 6 HOH 13 521 17 HOH HOH B . P 6 HOH 14 522 18 HOH HOH B . P 6 HOH 15 523 523 HOH HOH B . P 6 HOH 16 524 524 HOH HOH B . P 6 HOH 17 525 525 HOH HOH B . P 6 HOH 18 526 526 HOH HOH B . P 6 HOH 19 527 20 HOH HOH B . P 6 HOH 20 528 528 HOH HOH B . P 6 HOH 21 529 529 HOH HOH B . P 6 HOH 22 530 21 HOH HOH B . P 6 HOH 23 531 27 HOH HOH B . P 6 HOH 24 532 532 HOH HOH B . P 6 HOH 25 533 533 HOH HOH B . P 6 HOH 26 534 31 HOH HOH B . P 6 HOH 27 535 33 HOH HOH B . P 6 HOH 28 536 34 HOH HOH B . P 6 HOH 29 537 537 HOH HOH B . P 6 HOH 30 538 35 HOH HOH B . P 6 HOH 31 539 539 HOH HOH B . P 6 HOH 32 540 540 HOH HOH B . P 6 HOH 33 541 541 HOH HOH B . P 6 HOH 34 542 542 HOH HOH B . P 6 HOH 35 543 37 HOH HOH B . P 6 HOH 36 544 544 HOH HOH B . P 6 HOH 37 545 545 HOH HOH B . P 6 HOH 38 546 546 HOH HOH B . P 6 HOH 39 547 547 HOH HOH B . P 6 HOH 40 548 548 HOH HOH B . P 6 HOH 41 549 39 HOH HOH B . P 6 HOH 42 551 551 HOH HOH B . P 6 HOH 43 552 40 HOH HOH B . P 6 HOH 44 553 553 HOH HOH B . P 6 HOH 45 554 554 HOH HOH B . P 6 HOH 46 555 41 HOH HOH B . P 6 HOH 47 556 43 HOH HOH B . P 6 HOH 48 557 44 HOH HOH B . P 6 HOH 49 558 558 HOH HOH B . P 6 HOH 50 559 45 HOH HOH B . P 6 HOH 51 560 560 HOH HOH B . P 6 HOH 52 561 561 HOH HOH B . P 6 HOH 53 562 562 HOH HOH B . P 6 HOH 54 563 563 HOH HOH B . P 6 HOH 55 564 50 HOH HOH B . P 6 HOH 56 565 565 HOH HOH B . P 6 HOH 57 566 51 HOH HOH B . P 6 HOH 58 567 53 HOH HOH B . P 6 HOH 59 568 57 HOH HOH B . P 6 HOH 60 569 569 HOH HOH B . P 6 HOH 61 570 570 HOH HOH B . P 6 HOH 62 571 59 HOH HOH B . P 6 HOH 63 572 62 HOH HOH B . P 6 HOH 64 573 63 HOH HOH B . P 6 HOH 65 574 574 HOH HOH B . P 6 HOH 66 575 575 HOH HOH B . P 6 HOH 67 576 576 HOH HOH B . P 6 HOH 68 577 577 HOH HOH B . P 6 HOH 69 578 67 HOH HOH B . P 6 HOH 70 579 579 HOH HOH B . P 6 HOH 71 580 580 HOH HOH B . P 6 HOH 72 581 70 HOH HOH B . P 6 HOH 73 582 582 HOH HOH B . P 6 HOH 74 583 71 HOH HOH B . P 6 HOH 75 584 584 HOH HOH B . P 6 HOH 76 585 585 HOH HOH B . P 6 HOH 77 586 72 HOH HOH B . P 6 HOH 78 587 587 HOH HOH B . P 6 HOH 79 588 588 HOH HOH B . P 6 HOH 80 589 589 HOH HOH B . P 6 HOH 81 590 74 HOH HOH B . P 6 HOH 82 591 75 HOH HOH B . P 6 HOH 83 592 78 HOH HOH B . P 6 HOH 84 593 593 HOH HOH B . P 6 HOH 85 594 80 HOH HOH B . P 6 HOH 86 595 81 HOH HOH B . P 6 HOH 87 596 82 HOH HOH B . P 6 HOH 88 597 597 HOH HOH B . P 6 HOH 89 598 598 HOH HOH B . P 6 HOH 90 599 599 HOH HOH B . P 6 HOH 91 600 600 HOH HOH B . P 6 HOH 92 601 85 HOH HOH B . P 6 HOH 93 602 86 HOH HOH B . P 6 HOH 94 603 603 HOH HOH B . P 6 HOH 95 604 88 HOH HOH B . P 6 HOH 96 605 605 HOH HOH B . P 6 HOH 97 606 89 HOH HOH B . P 6 HOH 98 607 91 HOH HOH B . P 6 HOH 99 608 92 HOH HOH B . P 6 HOH 100 609 609 HOH HOH B . P 6 HOH 101 610 95 HOH HOH B . P 6 HOH 102 611 98 HOH HOH B . P 6 HOH 103 612 612 HOH HOH B . P 6 HOH 104 613 613 HOH HOH B . P 6 HOH 105 614 614 HOH HOH B . P 6 HOH 106 615 615 HOH HOH B . P 6 HOH 107 616 100 HOH HOH B . P 6 HOH 108 617 101 HOH HOH B . P 6 HOH 109 618 618 HOH HOH B . P 6 HOH 110 619 103 HOH HOH B . P 6 HOH 111 620 107 HOH HOH B . P 6 HOH 112 621 621 HOH HOH B . P 6 HOH 113 622 622 HOH HOH B . P 6 HOH 114 623 623 HOH HOH B . P 6 HOH 115 624 624 HOH HOH B . P 6 HOH 116 625 112 HOH HOH B . P 6 HOH 117 626 114 HOH HOH B . P 6 HOH 118 627 627 HOH HOH B . P 6 HOH 119 628 116 HOH HOH B . P 6 HOH 120 629 629 HOH HOH B . P 6 HOH 121 630 630 HOH HOH B . P 6 HOH 122 631 118 HOH HOH B . P 6 HOH 123 632 632 HOH HOH B . P 6 HOH 124 633 119 HOH HOH B . P 6 HOH 125 634 634 HOH HOH B . P 6 HOH 126 635 120 HOH HOH B . P 6 HOH 127 636 636 HOH HOH B . P 6 HOH 128 637 637 HOH HOH B . P 6 HOH 129 638 122 HOH HOH B . P 6 HOH 130 639 124 HOH HOH B . P 6 HOH 131 640 126 HOH HOH B . P 6 HOH 132 641 641 HOH HOH B . P 6 HOH 133 642 128 HOH HOH B . P 6 HOH 134 643 130 HOH HOH B . P 6 HOH 135 644 131 HOH HOH B . P 6 HOH 136 645 134 HOH HOH B . P 6 HOH 137 646 135 HOH HOH B . P 6 HOH 138 647 139 HOH HOH B . P 6 HOH 139 648 140 HOH HOH B . P 6 HOH 140 649 649 HOH HOH B . P 6 HOH 141 651 651 HOH HOH B . P 6 HOH 142 652 652 HOH HOH B . P 6 HOH 143 653 142 HOH HOH B . P 6 HOH 144 654 654 HOH HOH B . P 6 HOH 145 655 143 HOH HOH B . P 6 HOH 146 656 144 HOH HOH B . P 6 HOH 147 657 657 HOH HOH B . P 6 HOH 148 658 658 HOH HOH B . P 6 HOH 149 659 659 HOH HOH B . P 6 HOH 150 660 149 HOH HOH B . P 6 HOH 151 661 661 HOH HOH B . P 6 HOH 152 662 151 HOH HOH B . P 6 HOH 153 663 663 HOH HOH B . P 6 HOH 154 664 153 HOH HOH B . P 6 HOH 155 665 665 HOH HOH B . P 6 HOH 156 666 154 HOH HOH B . P 6 HOH 157 667 156 HOH HOH B . P 6 HOH 158 668 157 HOH HOH B . P 6 HOH 159 669 669 HOH HOH B . P 6 HOH 160 670 158 HOH HOH B . P 6 HOH 161 671 671 HOH HOH B . P 6 HOH 162 672 160 HOH HOH B . P 6 HOH 163 673 673 HOH HOH B . P 6 HOH 164 674 162 HOH HOH B . P 6 HOH 165 675 163 HOH HOH B . P 6 HOH 166 676 676 HOH HOH B . P 6 HOH 167 677 677 HOH HOH B . P 6 HOH 168 678 164 HOH HOH B . P 6 HOH 169 679 167 HOH HOH B . P 6 HOH 170 680 680 HOH HOH B . P 6 HOH 171 681 681 HOH HOH B . P 6 HOH 172 682 682 HOH HOH B . P 6 HOH 173 683 170 HOH HOH B . P 6 HOH 174 684 173 HOH HOH B . P 6 HOH 175 685 177 HOH HOH B . P 6 HOH 176 686 686 HOH HOH B . P 6 HOH 177 687 178 HOH HOH B . P 6 HOH 178 688 688 HOH HOH B . P 6 HOH 179 689 179 HOH HOH B . P 6 HOH 180 690 180 HOH HOH B . P 6 HOH 181 691 182 HOH HOH B . P 6 HOH 182 692 692 HOH HOH B . P 6 HOH 183 693 693 HOH HOH B . P 6 HOH 184 694 183 HOH HOH B . P 6 HOH 185 695 695 HOH HOH B . P 6 HOH 186 696 184 HOH HOH B . P 6 HOH 187 697 697 HOH HOH B . P 6 HOH 188 698 698 HOH HOH B . P 6 HOH 189 699 188 HOH HOH B . P 6 HOH 190 700 700 HOH HOH B . P 6 HOH 191 701 701 HOH HOH B . P 6 HOH 192 702 702 HOH HOH B . P 6 HOH 193 703 703 HOH HOH B . P 6 HOH 194 704 704 HOH HOH B . P 6 HOH 195 705 189 HOH HOH B . P 6 HOH 196 706 190 HOH HOH B . P 6 HOH 197 707 707 HOH HOH B . P 6 HOH 198 708 191 HOH HOH B . P 6 HOH 199 709 709 HOH HOH B . P 6 HOH 200 710 710 HOH HOH B . P 6 HOH 201 711 711 HOH HOH B . P 6 HOH 202 712 193 HOH HOH B . P 6 HOH 203 713 196 HOH HOH B . P 6 HOH 204 714 197 HOH HOH B . P 6 HOH 205 715 198 HOH HOH B . P 6 HOH 206 716 200 HOH HOH B . P 6 HOH 207 717 201 HOH HOH B . P 6 HOH 208 718 205 HOH HOH B . P 6 HOH 209 719 719 HOH HOH B . P 6 HOH 210 720 720 HOH HOH B . P 6 HOH 211 721 208 HOH HOH B . P 6 HOH 212 722 722 HOH HOH B . P 6 HOH 213 723 723 HOH HOH B . P 6 HOH 214 724 724 HOH HOH B . P 6 HOH 215 725 211 HOH HOH B . P 6 HOH 216 726 214 HOH HOH B . P 6 HOH 217 727 215 HOH HOH B . P 6 HOH 218 728 728 HOH HOH B . P 6 HOH 219 729 729 HOH HOH B . P 6 HOH 220 730 730 HOH HOH B . P 6 HOH 221 731 217 HOH HOH B . P 6 HOH 222 732 732 HOH HOH B . P 6 HOH 223 733 733 HOH HOH B . P 6 HOH 224 734 218 HOH HOH B . P 6 HOH 225 735 735 HOH HOH B . P 6 HOH 226 736 219 HOH HOH B . P 6 HOH 227 737 737 HOH HOH B . P 6 HOH 228 738 220 HOH HOH B . P 6 HOH 229 739 739 HOH HOH B . P 6 HOH 230 740 740 HOH HOH B . P 6 HOH 231 741 221 HOH HOH B . P 6 HOH 232 742 742 HOH HOH B . P 6 HOH 233 743 743 HOH HOH B . P 6 HOH 234 744 744 HOH HOH B . P 6 HOH 235 745 223 HOH HOH B . P 6 HOH 236 746 225 HOH HOH B . P 6 HOH 237 747 231 HOH HOH B . P 6 HOH 238 748 233 HOH HOH B . P 6 HOH 239 749 235 HOH HOH B . P 6 HOH 240 751 751 HOH HOH B . P 6 HOH 241 752 237 HOH HOH B . P 6 HOH 242 753 238 HOH HOH B . P 6 HOH 243 754 754 HOH HOH B . P 6 HOH 244 755 240 HOH HOH B . P 6 HOH 245 756 756 HOH HOH B . P 6 HOH 246 757 757 HOH HOH B . P 6 HOH 247 758 758 HOH HOH B . P 6 HOH 248 759 241 HOH HOH B . P 6 HOH 249 760 242 HOH HOH B . P 6 HOH 250 761 247 HOH HOH B . P 6 HOH 251 762 252 HOH HOH B . P 6 HOH 252 763 253 HOH HOH B . P 6 HOH 253 764 254 HOH HOH B . P 6 HOH 254 765 255 HOH HOH B . P 6 HOH 255 766 257 HOH HOH B . P 6 HOH 256 767 258 HOH HOH B . P 6 HOH 257 768 768 HOH HOH B . P 6 HOH 258 769 261 HOH HOH B . P 6 HOH 259 770 770 HOH HOH B . P 6 HOH 260 771 266 HOH HOH B . P 6 HOH 261 772 267 HOH HOH B . P 6 HOH 262 773 270 HOH HOH B . P 6 HOH 263 774 272 HOH HOH B . P 6 HOH 264 775 274 HOH HOH B . P 6 HOH 265 776 776 HOH HOH B . P 6 HOH 266 777 276 HOH HOH B . P 6 HOH 267 778 778 HOH HOH B . P 6 HOH 268 779 779 HOH HOH B . P 6 HOH 269 780 280 HOH HOH B . P 6 HOH 270 781 781 HOH HOH B . P 6 HOH 271 782 782 HOH HOH B . P 6 HOH 272 783 282 HOH HOH B . P 6 HOH 273 784 283 HOH HOH B . P 6 HOH 274 785 785 HOH HOH B . P 6 HOH 275 786 786 HOH HOH B . P 6 HOH 276 787 286 HOH HOH B . P 6 HOH 277 788 788 HOH HOH B . P 6 HOH 278 789 789 HOH HOH B . P 6 HOH 279 790 291 HOH HOH B . P 6 HOH 280 791 791 HOH HOH B . P 6 HOH 281 792 294 HOH HOH B . P 6 HOH 282 793 793 HOH HOH B . P 6 HOH 283 794 295 HOH HOH B . P 6 HOH 284 795 795 HOH HOH B . P 6 HOH 285 796 296 HOH HOH B . P 6 HOH 286 797 299 HOH HOH B . P 6 HOH 287 798 798 HOH HOH B . P 6 HOH 288 799 799 HOH HOH B . P 6 HOH 289 800 301 HOH HOH B . P 6 HOH 290 801 303 HOH HOH B . P 6 HOH 291 802 802 HOH HOH B . P 6 HOH 292 803 803 HOH HOH B . P 6 HOH 293 804 804 HOH HOH B . P 6 HOH 294 805 805 HOH HOH B . P 6 HOH 295 806 305 HOH HOH B . P 6 HOH 296 807 807 HOH HOH B . P 6 HOH 297 808 306 HOH HOH B . P 6 HOH 298 809 307 HOH HOH B . P 6 HOH 299 810 310 HOH HOH B . P 6 HOH 300 811 312 HOH HOH B . P 6 HOH 301 812 313 HOH HOH B . P 6 HOH 302 813 316 HOH HOH B . P 6 HOH 303 814 814 HOH HOH B . P 6 HOH 304 815 815 HOH HOH B . P 6 HOH 305 816 317 HOH HOH B . P 6 HOH 306 817 817 HOH HOH B . P 6 HOH 307 818 319 HOH HOH B . P 6 HOH 308 819 819 HOH HOH B . P 6 HOH 309 820 320 HOH HOH B . P 6 HOH 310 821 330 HOH HOH B . P 6 HOH 311 822 331 HOH HOH B . P 6 HOH 312 823 336 HOH HOH B . P 6 HOH 313 824 341 HOH HOH B . P 6 HOH 314 825 346 HOH HOH B . P 6 HOH 315 826 348 HOH HOH B . P 6 HOH 316 827 349 HOH HOH B . P 6 HOH 317 828 350 HOH HOH B . P 6 HOH 318 829 829 HOH HOH B . P 6 HOH 319 830 351 HOH HOH B . P 6 HOH 320 831 352 HOH HOH B . P 6 HOH 321 832 353 HOH HOH B . P 6 HOH 322 833 354 HOH HOH B . P 6 HOH 323 834 834 HOH HOH B . P 6 HOH 324 835 355 HOH HOH B . P 6 HOH 325 836 356 HOH HOH B . P 6 HOH 326 837 360 HOH HOH B . P 6 HOH 327 838 838 HOH HOH B . P 6 HOH 328 839 839 HOH HOH B . P 6 HOH 329 840 840 HOH HOH B . P 6 HOH 330 841 362 HOH HOH B . P 6 HOH 331 842 842 HOH HOH B . P 6 HOH 332 843 363 HOH HOH B . P 6 HOH 333 844 364 HOH HOH B . P 6 HOH 334 845 365 HOH HOH B . P 6 HOH 335 846 366 HOH HOH B . P 6 HOH 336 847 367 HOH HOH B . P 6 HOH 337 848 368 HOH HOH B . P 6 HOH 338 849 849 HOH HOH B . P 6 HOH 339 851 370 HOH HOH B . P 6 HOH 340 852 372 HOH HOH B . P 6 HOH 341 853 373 HOH HOH B . P 6 HOH 342 854 374 HOH HOH B . P 6 HOH 343 855 375 HOH HOH B . P 6 HOH 344 856 377 HOH HOH B . P 6 HOH 345 857 378 HOH HOH B . P 6 HOH 346 858 379 HOH HOH B . P 6 HOH 347 859 386 HOH HOH B . P 6 HOH 348 860 387 HOH HOH B . P 6 HOH 349 861 388 HOH HOH B . P 6 HOH 350 862 389 HOH HOH B . P 6 HOH 351 863 391 HOH HOH B . P 6 HOH 352 864 392 HOH HOH B . P 6 HOH 353 865 395 HOH HOH B . P 6 HOH 354 866 396 HOH HOH B . P 6 HOH 355 867 399 HOH HOH B . P 6 HOH 356 868 400 HOH HOH B . P 6 HOH 357 869 403 HOH HOH B . P 6 HOH 358 870 405 HOH HOH B . P 6 HOH 359 871 407 HOH HOH B . P 6 HOH 360 872 415 HOH HOH B . P 6 HOH 361 873 416 HOH HOH B . P 6 HOH 362 874 417 HOH HOH B . P 6 HOH 363 875 418 HOH HOH B . P 6 HOH 364 876 419 HOH HOH B . P 6 HOH 365 877 420 HOH HOH B . P 6 HOH 366 878 422 HOH HOH B . P 6 HOH 367 879 426 HOH HOH B . P 6 HOH 368 880 427 HOH HOH B . P 6 HOH 369 881 428 HOH HOH B . P 6 HOH 370 882 429 HOH HOH B . P 6 HOH 371 883 432 HOH HOH B . P 6 HOH 372 884 433 HOH HOH B . P 6 HOH 373 885 437 HOH HOH B . P 6 HOH 374 886 438 HOH HOH B . P 6 HOH 375 887 442 HOH HOH B . P 6 HOH 376 888 443 HOH HOH B . P 6 HOH 377 889 446 HOH HOH B . P 6 HOH 378 890 449 HOH HOH B . P 6 HOH 379 891 453 HOH HOH B . P 6 HOH 380 892 456 HOH HOH B . P 6 HOH 381 893 462 HOH HOH B . P 6 HOH 382 894 463 HOH HOH B . P 6 HOH 383 895 465 HOH HOH B . P 6 HOH 384 896 466 HOH HOH B . P 6 HOH 385 897 468 HOH HOH B . P 6 HOH 386 898 469 HOH HOH B . P 6 HOH 387 899 470 HOH HOH B . P 6 HOH 388 900 471 HOH HOH B . P 6 HOH 389 901 472 HOH HOH B . P 6 HOH 390 902 473 HOH HOH B . P 6 HOH 391 903 474 HOH HOH B . P 6 HOH 392 904 476 HOH HOH B . P 6 HOH 393 905 478 HOH HOH B . P 6 HOH 394 906 482 HOH HOH B . P 6 HOH 395 907 484 HOH HOH B . P 6 HOH 396 908 489 HOH HOH B . P 6 HOH 397 909 490 HOH HOH B . P 6 HOH 398 910 491 HOH HOH B . P 6 HOH 399 911 492 HOH HOH B . P 6 HOH 400 912 493 HOH HOH B . P 6 HOH 401 913 495 HOH HOH B . P 6 HOH 402 914 496 HOH HOH B . P 6 HOH 403 915 498 HOH HOH B . P 6 HOH 404 916 499 HOH HOH B . P 6 HOH 405 917 750 HOH HOH B . P 6 HOH 406 918 94 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 B ASN 101 B ASN 101 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 101 A ASN 101 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 159 A ASN 159 ? ASN 'GLYCOSYLATION SITE' 4 B ASN 159 B ASN 159 ? ASN 'GLYCOSYLATION SITE' 5 A ASN 352 A ASN 352 ? ASN 'GLYCOSYLATION SITE' 6 B ASN 352 B ASN 352 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 6990 ? 1 MORE -2 ? 1 'SSA (A^2)' 38680 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 NE2 ? A HIS 88 ? A HIS 88 ? 1_555 ZN ? F ZN . ? A ZN 850 ? 1_555 NE2 ? A HIS 86 ? A HIS 86 ? 1_555 118.1 ? 2 NE2 ? A HIS 88 ? A HIS 88 ? 1_555 ZN ? F ZN . ? A ZN 850 ? 1_555 NE2 ? A HIS 330 ? A HIS 330 ? 1_555 101.8 ? 3 NE2 ? A HIS 86 ? A HIS 86 ? 1_555 ZN ? F ZN . ? A ZN 850 ? 1_555 NE2 ? A HIS 330 ? A HIS 330 ? 1_555 86.5 ? 4 NE2 ? A HIS 88 ? A HIS 88 ? 1_555 ZN ? F ZN . ? A ZN 850 ? 1_555 OD1 ? A ASP 415 ? A ASP 415 ? 1_555 71.8 ? 5 NE2 ? A HIS 86 ? A HIS 86 ? 1_555 ZN ? F ZN . ? A ZN 850 ? 1_555 OD1 ? A ASP 415 ? A ASP 415 ? 1_555 101.6 ? 6 NE2 ? A HIS 330 ? A HIS 330 ? 1_555 ZN ? F ZN . ? A ZN 850 ? 1_555 OD1 ? A ASP 415 ? A ASP 415 ? 1_555 171.3 ? 7 NE2 ? B HIS 88 ? B HIS 88 ? 1_555 ZN ? L ZN . ? B ZN 850 ? 1_555 NE2 ? B HIS 330 ? B HIS 330 ? 1_555 95.3 ? 8 NE2 ? B HIS 88 ? B HIS 88 ? 1_555 ZN ? L ZN . ? B ZN 850 ? 1_555 NE2 ? B HIS 86 ? B HIS 86 ? 1_555 120.8 ? 9 NE2 ? B HIS 330 ? B HIS 330 ? 1_555 ZN ? L ZN . ? B ZN 850 ? 1_555 NE2 ? B HIS 86 ? B HIS 86 ? 1_555 91.4 ? 10 NE2 ? B HIS 88 ? B HIS 88 ? 1_555 ZN ? L ZN . ? B ZN 850 ? 1_555 OD1 ? B ASP 415 ? B ASP 415 ? 1_555 86.8 ? 11 NE2 ? B HIS 330 ? B HIS 330 ? 1_555 ZN ? L ZN . ? B ZN 850 ? 1_555 OD1 ? B ASP 415 ? B ASP 415 ? 1_555 177.7 ? 12 NE2 ? B HIS 86 ? B HIS 86 ? 1_555 ZN ? L ZN . ? B ZN 850 ? 1_555 OD1 ? B ASP 415 ? B ASP 415 ? 1_555 88.5 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2010-02-09 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal DNA 'data collection' . ? 1 PHENIX 'model building' . ? 2 REFMAC refinement 5.5.0102 ? 3 MOSFLM 'data reduction' . ? 4 SCALA 'data scaling' . ? 5 PHENIX phasing . ? 6 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OG A SER 372 ? ? O A HOH 841 ? ? 2.04 2 1 NH2 B ARG 199 ? ? O B HOH 805 ? ? 2.13 # _pdbx_validate_symm_contact.id 1 _pdbx_validate_symm_contact.PDB_model_num 1 _pdbx_validate_symm_contact.auth_atom_id_1 O _pdbx_validate_symm_contact.auth_asym_id_1 B _pdbx_validate_symm_contact.auth_comp_id_1 HOH _pdbx_validate_symm_contact.auth_seq_id_1 801 _pdbx_validate_symm_contact.PDB_ins_code_1 ? _pdbx_validate_symm_contact.label_alt_id_1 ? _pdbx_validate_symm_contact.site_symmetry_1 1_555 _pdbx_validate_symm_contact.auth_atom_id_2 O _pdbx_validate_symm_contact.auth_asym_id_2 B _pdbx_validate_symm_contact.auth_comp_id_2 HOH _pdbx_validate_symm_contact.auth_seq_id_2 838 _pdbx_validate_symm_contact.PDB_ins_code_2 ? _pdbx_validate_symm_contact.label_alt_id_2 ? _pdbx_validate_symm_contact.site_symmetry_2 1_655 _pdbx_validate_symm_contact.dist 2.07 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASN A 101 ? ? -100.40 -60.05 2 1 SER A 130 ? ? -113.25 -163.49 3 1 HIS A 358 ? ? 72.23 -68.12 4 1 ASP A 415 ? ? 71.15 -85.21 5 1 ASN B 101 ? ? -100.70 -66.38 6 1 HIS B 358 ? ? 71.31 -72.85 7 1 ASP B 415 ? ? 74.12 -85.31 # _pdbx_validate_chiral.id 1 _pdbx_validate_chiral.PDB_model_num 1 _pdbx_validate_chiral.auth_atom_id C1 _pdbx_validate_chiral.label_alt_id ? _pdbx_validate_chiral.auth_asym_id B _pdbx_validate_chiral.auth_comp_id NAG _pdbx_validate_chiral.auth_seq_id 550 _pdbx_validate_chiral.PDB_ins_code ? _pdbx_validate_chiral.details 'WRONG HAND' _pdbx_validate_chiral.omega . # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A LYS 324 ? CG ? A LYS 324 CG 2 1 Y 1 A LYS 324 ? CD ? A LYS 324 CD 3 1 Y 1 A LYS 324 ? CE ? A LYS 324 CE 4 1 Y 1 A LYS 324 ? NZ ? A LYS 324 NZ # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLY 1 ? A GLY 1 2 1 Y 1 A GLY 2 ? A GLY 2 3 1 Y 1 A LYS 485 ? A LYS 485 4 1 Y 1 A GLY 486 ? A GLY 486 5 1 Y 1 A SER 487 ? A SER 487 6 1 Y 1 A LEU 488 ? A LEU 488 7 1 Y 1 A HIS 489 ? A HIS 489 8 1 Y 1 A HIS 490 ? A HIS 490 9 1 Y 1 A ILE 491 ? A ILE 491 10 1 Y 1 A LEU 492 ? A LEU 492 11 1 Y 1 A ASP 493 ? A ASP 493 12 1 Y 1 A ALA 494 ? A ALA 494 13 1 Y 1 A GLN 495 ? A GLN 495 14 1 Y 1 A LYS 496 ? A LYS 496 15 1 Y 1 A MET 497 ? A MET 497 16 1 Y 1 A VAL 498 ? A VAL 498 17 1 Y 1 A TRP 499 ? A TRP 499 18 1 Y 1 A ASN 500 ? A ASN 500 19 1 Y 1 A HIS 501 ? A HIS 501 20 1 Y 1 A ARG 502 ? A ARG 502 21 1 Y 1 A HIS 503 ? A HIS 503 22 1 Y 1 A HIS 504 ? A HIS 504 23 1 Y 1 A HIS 505 ? A HIS 505 24 1 Y 1 A HIS 506 ? A HIS 506 25 1 Y 1 A HIS 507 ? A HIS 507 26 1 Y 1 A HIS 508 ? A HIS 508 27 1 Y 1 B GLY 1 ? B GLY 1 28 1 Y 1 B GLY 2 ? B GLY 2 29 1 Y 1 B LYS 485 ? B LYS 485 30 1 Y 1 B GLY 486 ? B GLY 486 31 1 Y 1 B SER 487 ? B SER 487 32 1 Y 1 B LEU 488 ? B LEU 488 33 1 Y 1 B HIS 489 ? B HIS 489 34 1 Y 1 B HIS 490 ? B HIS 490 35 1 Y 1 B ILE 491 ? B ILE 491 36 1 Y 1 B LEU 492 ? B LEU 492 37 1 Y 1 B ASP 493 ? B ASP 493 38 1 Y 1 B ALA 494 ? B ALA 494 39 1 Y 1 B GLN 495 ? B GLN 495 40 1 Y 1 B LYS 496 ? B LYS 496 41 1 Y 1 B MET 497 ? B MET 497 42 1 Y 1 B VAL 498 ? B VAL 498 43 1 Y 1 B TRP 499 ? B TRP 499 44 1 Y 1 B ASN 500 ? B ASN 500 45 1 Y 1 B HIS 501 ? B HIS 501 46 1 Y 1 B ARG 502 ? B ARG 502 47 1 Y 1 B HIS 503 ? B HIS 503 48 1 Y 1 B HIS 504 ? B HIS 504 49 1 Y 1 B HIS 505 ? B HIS 505 50 1 Y 1 B HIS 506 ? B HIS 506 51 1 Y 1 B HIS 507 ? B HIS 507 52 1 Y 1 B HIS 508 ? B HIS 508 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'ZINC ION' ZN 4 1,2-ETHANEDIOL EDO 5 'UNKNOWN ATOM OR ION' UNX 6 water HOH #